# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- CAF1 PF04857.20 EGR26864.1 - 1.1e-08 34.6 7.8 2.7e-07 30.1 2.0 2.9 2 1 0 2 2 2 2 CAF1 family ribonuclease GYD PF08734.11 EGR26865.1 - 0.022 14.7 0.5 56 3.8 0.0 3.3 3 0 0 3 3 3 0 GYD domain TPR_11 PF13414.6 EGR26865.1 - 0.038 13.7 0.8 62 3.4 0.0 3.5 3 0 0 3 3 3 0 TPR repeat Strep_pep PF14404.6 EGR26865.1 - 0.16 12.3 9.8 30 5.0 0.1 4.5 4 0 0 4 4 4 0 Ribosomally synthesized peptide in Streptomyces species DUF2755 PF10954.8 EGR26865.1 - 0.24 11.3 17.1 3.9 7.5 0.4 4.0 1 1 3 4 4 4 0 Protein of unknown function (DUF2755) Baseplate_J PF04865.14 EGR26865.1 - 0.28 10.3 3.5 34 3.5 0.0 3.5 4 0 0 4 4 4 0 Baseplate J-like protein HemY_N PF07219.13 EGR26865.1 - 1.6 8.9 12.6 23 5.2 0.2 4.0 3 1 1 4 4 4 0 HemY protein N-terminus FixQ PF05545.11 EGR26865.1 - 8.2 6.5 11.5 74 3.4 0.0 4.5 4 0 0 4 4 4 0 Cbb3-type cytochrome oxidase component FixQ Peptidase_M8 PF01457.16 EGR26867.1 - 4.1e-12 45.6 0.8 1.9e-05 23.5 0.1 2.1 2 0 0 2 2 2 2 Leishmanolysin His_Phos_2 PF00328.22 EGR26868.1 - 3.3e-13 49.8 0.7 1.3e-11 44.5 0.0 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Attractin PF08037.11 EGR26869.1 - 0.025 14.6 0.3 0.053 13.5 0.1 1.6 2 0 0 2 2 2 0 Attractin family Peptidase_M8 PF01457.16 EGR26870.1 - 1.4e-20 73.5 0.0 1.7e-20 73.3 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin WLM PF08325.10 EGR26870.1 - 0.0009 19.4 0.1 0.0013 18.8 0.1 1.2 1 0 0 1 1 1 1 WLM domain Peptidase_M10 PF00413.24 EGR26870.1 - 0.0011 18.9 0.1 0.0015 18.4 0.1 1.2 1 0 0 1 1 1 1 Matrixin Zincin_1 PF06262.11 EGR26870.1 - 0.0012 18.9 0.3 0.0025 17.9 0.3 1.5 1 0 0 1 1 1 1 Zincin-like metallopeptidase Peptidase_M8 PF01457.16 EGR26871.1 - 4.7e-12 45.4 7.0 7.9e-11 41.3 7.0 2.0 1 1 0 1 1 1 1 Leishmanolysin His_Phos_2 PF00328.22 EGR26872.1 - 6e-15 55.5 2.2 2.5e-14 53.4 0.2 1.9 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Peptidase_C65 PF10275.9 EGR26872.1 - 0.012 15.1 0.5 0.02 14.3 0.5 1.3 1 0 0 1 1 1 0 Peptidase C65 Otubain Peptidase_M8 PF01457.16 EGR26873.1 - 3.1e-07 29.4 0.8 3.2e-07 29.4 0.8 1.0 1 0 0 1 1 1 1 Leishmanolysin Attractin PF08037.11 EGR26873.1 - 0.031 14.3 0.2 0.066 13.2 0.2 1.6 1 0 0 1 1 1 0 Attractin family His_Phos_2 PF00328.22 EGR26874.1 - 1.8e-14 53.9 2.9 3.8e-14 52.8 3.0 1.5 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Suv3_N PF18114.1 EGR26874.1 - 0.0012 18.9 0.1 0.0022 18.1 0.1 1.4 1 0 0 1 1 1 1 Suv3 helical N-terminal domain Peptidase_M8 PF01457.16 EGR26876.1 - 6.7e-24 84.5 10.1 6.3e-16 58.2 0.1 2.1 1 1 1 2 2 2 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR26876.1 - 8.7e-08 32.0 9.2 8.7e-08 32.0 9.2 3.4 3 0 0 3 3 3 1 Tenascin EGF domain EGF_2 PF07974.13 EGR26876.1 - 0.0092 16.3 12.6 0.0092 16.3 12.6 4.3 3 1 0 3 3 3 1 EGF-like domain Peptidase_M8 PF01457.16 EGR26877.1 - 1.4e-36 126.3 0.3 1.4e-36 126.3 0.3 2.8 2 1 1 3 3 3 1 Leishmanolysin EGF_Tenascin PF18720.1 EGR26877.1 - 4.3e-07 29.8 9.3 4.3e-07 29.8 9.3 3.2 3 0 0 3 3 3 1 Tenascin EGF domain MFS_1 PF07690.16 EGR26878.1 - 8.8e-11 41.3 11.6 8.8e-11 41.3 11.6 2.7 2 2 1 3 3 3 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGR26878.1 - 0.00072 18.5 14.3 0.016 14.1 6.9 2.3 1 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 EGR26878.1 - 0.29 9.4 12.7 0.11 10.8 2.0 2.5 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family Pkinase PF00069.25 EGR26879.1 - 1.5e-18 67.1 0.0 1.6e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR26879.1 - 1.1e-09 37.9 0.0 1.2e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR26879.1 - 0.0051 16.2 0.0 0.0052 16.1 0.0 1.1 1 0 0 1 1 1 1 Kinase-like TTL PF03133.15 EGR26880.1 - 4.2e-54 183.7 11.2 7e-54 182.9 11.2 1.4 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR26880.1 - 7.8e-08 31.9 3.1 0.00022 20.6 0.1 2.7 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR26880.1 - 0.0002 20.7 0.8 0.0063 15.8 0.0 2.8 2 1 1 3 3 3 1 Sugar-transfer associated ATP-grasp RimK PF08443.11 EGR26880.1 - 0.0035 17.0 2.2 0.5 9.9 0.0 2.4 2 1 0 2 2 2 2 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 EGR26880.1 - 0.05 13.0 0.1 0.097 12.1 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain Peptidase_M8 PF01457.16 EGR26881.1 - 1e-12 47.6 1.8 1.5e-08 33.8 0.0 2.3 2 0 0 2 2 2 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR26881.1 - 2.8e-05 24.0 4.2 2.8e-05 24.0 4.2 1.9 2 0 0 2 2 2 1 Tenascin EGF domain PTSIIA_gutA PF03829.13 EGR26881.1 - 0.13 12.1 0.3 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 PTS system glucitol/sorbitol-specific IIA component Peptidase_M8 PF01457.16 EGR26882.1 - 1.1e-27 96.9 0.2 2.8e-24 85.7 0.1 2.2 1 1 1 2 2 2 2 Leishmanolysin Nucleos_tra2_N PF01773.20 EGR26882.1 - 0.15 12.7 0.0 0.37 11.4 0.0 1.6 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter N-terminus Peptidase_M8 PF01457.16 EGR26883.1 - 2.4e-38 132.1 0.2 3.3e-38 131.7 0.2 1.1 1 0 0 1 1 1 1 Leishmanolysin Zincin_1 PF06262.11 EGR26883.1 - 0.022 14.9 0.2 0.051 13.7 0.2 1.6 1 0 0 1 1 1 0 Zincin-like metallopeptidase EGF_2 PF07974.13 EGR26884.1 - 0.001 19.4 11.0 0.001 19.4 11.0 4.1 4 1 0 4 4 4 1 EGF-like domain EGF_Tenascin PF18720.1 EGR26884.1 - 0.69 10.0 7.9 0.1 12.6 2.8 2.4 2 0 0 2 2 2 0 Tenascin EGF domain Peptidase_M8 PF01457.16 EGR26885.1 - 1.3e-24 86.9 0.0 1.4e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin BSP PF04450.12 EGR26885.1 - 0.011 15.5 0.0 0.024 14.4 0.0 1.5 1 1 1 2 2 2 0 Peptidase of plants and bacteria Zincin_1 PF06262.11 EGR26885.1 - 0.056 13.6 0.1 0.1 12.7 0.1 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase NCBP3 PF10309.9 EGR26886.1 - 0.044 13.6 0.1 0.15 12.0 0.0 1.8 1 1 1 2 2 2 0 Nuclear cap-binding protein subunit 3 Peptidase_M8 PF01457.16 EGR26886.1 - 0.071 11.8 0.0 0.099 11.3 0.0 1.2 1 1 0 1 1 1 0 Leishmanolysin Peptidase_M8 PF01457.16 EGR26887.1 - 4.2e-44 151.1 6.6 3.8e-39 134.8 0.2 2.1 1 1 1 2 2 2 2 Leishmanolysin EGF_2 PF07974.13 EGR26887.1 - 0.0072 16.7 12.8 0.0072 16.7 12.8 3.0 3 1 0 3 3 3 1 EGF-like domain Zincin_1 PF06262.11 EGR26887.1 - 0.017 15.2 0.4 0.038 14.1 0.4 1.5 1 0 0 1 1 1 0 Zincin-like metallopeptidase EGF_Tenascin PF18720.1 EGR26887.1 - 0.024 14.7 3.0 0.024 14.7 3.0 2.0 2 0 0 2 2 2 0 Tenascin EGF domain Peptidase_M8 PF01457.16 EGR26888.1 - 5.4e-44 150.8 11.3 4.9e-39 134.4 0.0 2.3 2 1 1 3 3 3 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR26888.1 - 0.00013 21.9 10.2 0.00013 21.9 10.2 2.2 2 0 0 2 2 2 1 Tenascin EGF domain EGF_2 PF07974.13 EGR26888.1 - 0.00051 20.3 14.7 0.00051 20.3 14.7 3.5 4 0 0 4 4 4 1 EGF-like domain Zincin_1 PF06262.11 EGR26888.1 - 0.012 15.7 0.1 0.025 14.7 0.1 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase Peptidase_M8 PF01457.16 EGR26889.1 - 2.5e-45 155.2 8.0 6.1e-41 140.7 0.0 2.6 1 1 2 3 3 3 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR26889.1 - 0.00013 22.0 7.5 0.00032 20.7 7.5 1.8 1 0 0 1 1 1 1 Tenascin EGF domain EGF_2 PF07974.13 EGR26889.1 - 0.00076 19.8 14.2 0.00076 19.8 14.2 3.4 5 0 0 5 5 5 1 EGF-like domain Zincin_1 PF06262.11 EGR26889.1 - 0.037 14.1 0.0 0.074 13.2 0.0 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase Peptidase_M8 PF01457.16 EGR26890.1 - 5.9e-34 117.6 1.0 7.1e-34 117.4 1.0 1.0 1 0 0 1 1 1 1 Leishmanolysin RIIa PF02197.17 EGR26890.1 - 0.27 10.9 1.0 0.64 9.7 0.0 2.1 2 0 0 2 2 2 0 Regulatory subunit of type II PKA R-subunit Peptidase_M8 PF01457.16 EGR26891.1 - 1.6e-47 162.4 9.5 1.6e-41 142.7 0.1 2.3 1 1 1 2 2 2 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR26891.1 - 8.8e-05 22.5 11.6 0.00043 20.3 11.6 2.3 1 0 0 1 1 1 1 Tenascin EGF domain EGF_2 PF07974.13 EGR26891.1 - 0.00099 19.4 14.5 0.00099 19.4 14.5 3.6 4 0 0 4 4 4 1 EGF-like domain VSP PF03302.13 EGR26892.1 - 0.0012 17.8 26.9 0.0012 17.8 26.9 7.1 2 1 5 7 7 7 6 Giardia variant-specific surface protein Met_10 PF02475.16 EGR26893.1 - 1.8e-45 155.2 0.0 3.6e-45 154.2 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.18 EGR26893.1 - 0.00054 19.7 0.0 0.00094 18.9 0.0 1.3 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.13 EGR26893.1 - 0.001 18.5 0.1 0.0027 17.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EGR26893.1 - 0.015 15.2 0.0 0.052 13.4 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_15 PF09445.10 EGR26893.1 - 0.021 14.4 3.6 0.037 13.6 0.0 2.6 2 1 0 2 2 2 0 RNA cap guanine-N2 methyltransferase RNase_J_C PF17770.1 EGR26893.1 - 0.026 15.6 0.0 0.096 13.7 0.0 1.9 1 0 0 1 1 1 0 Ribonuclease J C-terminal domain PH_3 PF14593.6 EGR26893.1 - 0.028 14.5 0.4 0.11 12.6 0.3 2.0 1 1 0 1 1 1 0 PH domain MTS PF05175.14 EGR26893.1 - 0.031 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 EGR26893.1 - 0.083 13.6 0.0 0.22 12.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Hydrolase PF00702.26 EGR26894.1 - 5.9e-14 52.8 0.0 5.2e-10 40.0 0.0 2.6 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGR26894.1 - 1.6e-12 47.3 0.0 3.9e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGR26894.1 - 0.0041 16.9 4.6 0.0041 16.9 4.6 2.4 1 1 1 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EGR26894.1 - 0.029 14.1 4.2 0.039 13.7 0.1 2.4 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGR26894.1 - 0.11 12.6 0.0 0.48 10.6 0.0 2.0 2 0 0 2 2 2 0 Cation transport ATPase (P-type) Virulence_fact PF13769.6 EGR26894.1 - 0.15 12.3 0.1 0.32 11.3 0.1 1.5 1 0 0 1 1 1 0 Virulence factor PC_rep PF01851.22 EGR26895.1 - 1.4e-30 104.1 11.0 2e-06 27.9 0.0 8.3 7 0 0 7 7 7 6 Proteasome/cyclosome repeat RPN2_C PF18004.1 EGR26895.1 - 8.2e-28 97.3 10.3 8.2e-28 97.3 10.3 2.4 2 1 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain HEAT_2 PF13646.6 EGR26895.1 - 4.5e-11 43.0 0.0 1.6e-07 31.6 0.0 4.3 3 2 2 5 5 5 1 HEAT repeats DNA_alkylation PF08713.11 EGR26895.1 - 4.4e-05 23.3 0.1 0.3 10.8 0.0 3.4 3 1 0 3 3 3 2 DNA alkylation repair enzyme HEAT_EZ PF13513.6 EGR26895.1 - 0.004 17.6 0.0 1.1 9.9 0.0 4.0 3 1 1 4 4 4 1 HEAT-like repeat Nipped-B_C PF12830.7 EGR26895.1 - 0.021 14.7 7.7 0.049 13.6 1.0 3.2 2 1 2 4 4 4 0 Sister chromatid cohesion C-terminus Utp13 PF08625.11 EGR26895.1 - 0.035 14.0 0.1 0.035 14.0 0.1 3.5 4 0 0 4 4 4 0 Utp13 specific WD40 associated domain HEAT PF02985.22 EGR26895.1 - 0.33 11.3 1.4 62 4.3 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat GlutR_N PF05201.15 EGR26895.1 - 0.61 9.8 6.1 3 7.6 0.0 3.0 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, N-terminal domain Cnd1 PF12717.7 EGR26895.1 - 0.69 9.9 4.9 5.6 7.0 0.0 4.2 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 Latrophilin PF02354.16 EGR26895.1 - 0.77 8.8 5.4 1.4 8.0 5.4 1.3 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region Peptidase_C13 PF01650.18 EGR26897.1 - 4.8e-98 327.7 2.5 7.1e-98 327.2 2.5 1.3 1 0 0 1 1 1 1 Peptidase C13 family PseudoU_synth_2 PF00849.22 EGR26897.1 - 0.0029 17.7 0.6 0.063 13.4 0.1 2.1 2 0 0 2 2 2 1 RNA pseudouridylate synthase DUF2420 PF10336.9 EGR26897.1 - 0.058 13.4 5.1 0.086 12.9 1.9 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2420) Copine PF07002.16 EGR26899.1 - 5.9e-48 163.2 0.1 8.6e-48 162.7 0.1 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 EGR26899.1 - 3.3e-11 43.4 0.2 4.5e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EGR26899.1 - 1.9e-06 28.2 0.1 3.8e-06 27.2 0.1 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus Abhydrolase_2 PF02230.16 EGR26901.1 - 1.8e-10 41.0 0.0 2.2e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase CAP_GLY PF01302.25 EGR26902.1 - 3.9e-12 46.0 0.0 8e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 EGR26902.1 - 1.6e-07 31.6 51.5 0.00021 21.6 6.9 6.6 4 2 2 6 6 6 5 Leucine Rich repeats (2 copies) Ubiquitin_2 PF14560.6 EGR26902.1 - 3.1e-05 24.3 0.1 3.1e-05 24.3 0.1 3.0 3 0 0 3 3 3 1 Ubiquitin-like domain LRR_8 PF13855.6 EGR26902.1 - 0.013 15.3 42.4 0.031 14.0 5.5 6.5 2 2 3 5 5 5 0 Leucine rich repeat ubiquitin PF00240.23 EGR26902.1 - 0.057 13.2 2.3 0.39 10.5 0.1 3.2 2 1 0 2 2 2 0 Ubiquitin family LSDAT_prok PF18171.1 EGR26903.1 - 3.6e-29 101.4 0.0 4.8e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote SRA PF18491.1 EGR26903.1 - 0.078 13.1 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 SET and RING associated domain Peptidase_M8 PF01457.16 EGR26904.1 - 3.6e-41 141.5 5.8 5.8e-34 117.7 0.0 2.2 1 1 1 2 2 2 2 Leishmanolysin VSP PF03302.13 EGR26904.1 - 4.2e-05 22.6 19.0 4.2e-05 22.6 19.0 2.2 1 1 1 2 2 2 1 Giardia variant-specific surface protein EGF_Tenascin PF18720.1 EGR26904.1 - 0.0021 18.1 9.2 0.0099 15.9 9.2 2.3 1 0 0 1 1 1 1 Tenascin EGF domain Cas_Csy4 PF09618.10 EGR26904.1 - 0.004 17.3 0.0 0.0072 16.5 0.0 1.4 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Csy4) Peptidase_M8 PF01457.16 EGR26905.1 - 3.9e-30 105.0 13.5 1.6e-24 86.5 0.3 2.0 1 1 1 2 2 2 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR26905.1 - 8.6e-06 25.7 4.4 2.6e-05 24.2 4.4 1.9 1 0 0 1 1 1 1 Tenascin EGF domain WLM PF08325.10 EGR26905.1 - 0.00061 19.9 0.2 0.0013 18.8 0.0 1.6 2 0 0 2 2 2 1 WLM domain EGF_2 PF07974.13 EGR26905.1 - 0.0058 17.0 8.4 0.0058 17.0 8.4 4.2 5 0 0 5 5 5 1 EGF-like domain EGF PF00008.27 EGR26905.1 - 0.014 15.7 5.1 0.014 15.7 5.1 3.0 3 0 0 3 3 3 0 EGF-like domain Zincin_1 PF06262.11 EGR26905.1 - 0.017 15.2 0.1 0.036 14.2 0.1 1.5 1 0 0 1 1 1 0 Zincin-like metallopeptidase MCR_alpha PF02249.17 EGR26905.1 - 0.06 13.8 0.4 0.13 12.7 0.4 1.6 1 0 0 1 1 1 0 Methyl-coenzyme M reductase alpha subunit, C-terminal domain Tox-HNH-EHHH PF15657.6 EGR26905.1 - 0.098 13.0 0.2 0.26 11.7 0.2 1.7 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxins PepSY_2 PF13670.6 EGR26905.1 - 0.12 12.4 1.2 0.14 12.2 0.2 1.6 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain Peptidase_M8 PF01457.16 EGR26906.1 - 1.2e-40 139.8 8.5 1.2e-32 113.3 0.1 2.1 1 1 1 2 2 2 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR26906.1 - 0.00043 20.2 7.5 0.0016 18.4 7.5 2.1 1 0 0 1 1 1 1 Tenascin EGF domain MBT PF02820.18 EGR26906.1 - 0.047 14.0 0.3 0.13 12.6 0.1 1.9 2 0 0 2 2 2 0 mbt repeat Peptidase_M8 PF01457.16 EGR26907.1 - 1e-35 123.4 12.5 3.5e-34 118.4 6.9 2.3 2 1 0 2 2 2 1 Leishmanolysin EGF_2 PF07974.13 EGR26907.1 - 0.00026 21.3 15.5 0.00026 21.3 15.5 3.0 4 0 0 4 4 4 1 EGF-like domain EGF_Tenascin PF18720.1 EGR26907.1 - 0.0012 18.9 7.3 0.0012 18.9 7.3 2.1 2 0 0 2 2 2 1 Tenascin EGF domain Peptidase_M8 PF01457.16 EGR26910.1 - 7.2e-35 120.7 11.6 4.2e-30 104.9 0.0 2.1 1 1 1 2 2 2 2 Leishmanolysin EGF_2 PF07974.13 EGR26910.1 - 0.0027 18.0 11.3 0.0027 18.0 11.3 3.9 3 0 0 3 3 3 1 EGF-like domain EGF_Tenascin PF18720.1 EGR26910.1 - 0.015 15.4 5.3 0.015 15.4 5.3 2.9 3 0 0 3 3 3 0 Tenascin EGF domain EC042_2821 PF18740.1 EGR26910.1 - 0.13 12.2 1.6 0.25 11.2 1.6 1.4 1 0 0 1 1 1 0 EC042_2821-lke REase Pkinase PF00069.25 EGR26911.1 - 4.1e-26 91.9 1.9 4.8e-26 91.7 1.9 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR26911.1 - 1.1e-16 60.9 0.2 1.3e-16 60.6 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR26911.1 - 0.087 11.6 0.4 0.16 10.7 0.1 1.5 2 0 0 2 2 2 0 Fungal protein kinase Hydrolase PF00702.26 EGR26912.1 - 4.7e-09 36.8 0.1 0.0003 21.2 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EGR26912.1 - 0.0013 18.4 13.9 0.0013 18.4 13.9 2.2 1 1 1 2 2 2 1 Cation transporting ATPase, C-terminus GWT1 PF06423.12 EGR26912.1 - 10 6.3 21.8 0.02 15.0 8.3 2.6 1 1 1 2 2 2 0 GWT1 Adeno_E1B_19K PF01691.16 EGR26913.1 - 0.029 13.9 0.2 0.049 13.2 0.2 1.4 1 0 0 1 1 1 0 Adenovirus E1B 19K protein / small t-antigen Kinesin PF00225.23 EGR26914.1 - 3.8e-49 167.4 15.9 5.5e-49 166.9 15.9 1.3 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR26914.1 - 2.8e-22 79.3 8.7 2.8e-22 79.3 8.7 2.0 2 1 0 2 2 2 1 Microtubule binding PhoH PF02562.16 EGR26914.1 - 0.0041 16.6 0.3 0.0096 15.4 0.3 1.7 1 1 0 1 1 1 1 PhoH-like protein DEAD PF00270.29 EGR26914.1 - 0.014 15.1 2.1 0.04 13.7 2.1 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_16 PF13191.6 EGR26914.1 - 0.19 12.1 0.0 0.24 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 EGR26914.1 - 0.21 11.2 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EGR26914.1 - 6.6 6.7 17.1 37 4.3 17.1 2.2 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit DHC PF09626.10 EGR26914.1 - 9.2 7.2 8.0 1.4 9.8 2.1 2.4 2 1 0 2 2 2 0 Dihaem cytochrome c VSP PF03302.13 EGR26915.1 - 4.8e-06 25.7 33.5 4.8e-06 25.7 33.5 3.4 1 1 3 4 4 4 4 Giardia variant-specific surface protein Ephrin_rec_like PF07699.13 EGR26915.1 - 0.002 17.9 2.1 0.002 17.9 2.1 8.8 1 1 8 9 9 9 2 Putative ephrin-receptor like SET PF00856.28 EGR26916.1 - 3.6e-09 37.2 0.3 3.6e-09 37.2 0.3 3.3 3 2 0 3 3 3 1 SET domain preSET_CXC PF18264.1 EGR26916.1 - 2.9e-05 24.4 21.7 2.9e-05 24.4 21.7 3.8 4 1 0 4 4 4 1 CXC domain GIDA_assoc PF13932.6 EGR26916.1 - 1.4 9.1 8.6 0.082 13.1 2.2 2.2 2 0 0 2 2 2 0 GidA associated domain CoA_transf_3 PF02515.17 EGR26917.1 - 3.2e-56 191.1 0.0 4e-56 190.7 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III LisH PF08513.11 EGR26918.1 - 0.29 11.2 0.1 0.29 11.2 0.1 2.8 3 0 0 3 3 3 0 LisH V_ATPase_I PF01496.19 EGR26919.1 - 2.2e-233 776.8 41.3 2.5e-233 776.6 41.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family UPF0114 PF03350.16 EGR26919.1 - 0.34 11.1 3.8 0.4 10.9 0.2 2.8 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 SUIM_assoc PF16619.5 EGR26919.1 - 1.9 8.6 7.8 15 5.8 7.8 2.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 UDG PF03167.19 EGR26920.1 - 2.1e-11 44.0 0.0 2.6e-11 43.7 0.0 1.0 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Cation_ATPase_C PF00689.21 EGR26923.1 - 1.8e-25 89.7 15.3 1.8e-25 89.7 15.3 1.6 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 EGR26923.1 - 0.02 14.7 0.1 0.032 14.0 0.1 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase BphX PF06139.12 EGR26923.1 - 0.033 14.1 3.2 1.4 8.8 0.3 2.6 2 1 0 2 2 2 0 BphX-like Mito_carr PF00153.27 EGR26924.1 - 2.5e-33 113.9 0.0 1.5e-15 56.9 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein Serine_protease PF18405.1 EGR26924.1 - 0.0048 16.1 0.0 0.0074 15.5 0.0 1.5 1 0 0 1 1 1 1 Gammaproteobacterial serine protease Pribosyltran PF00156.27 EGR26925.1 - 4.3e-28 97.8 0.3 5.5e-28 97.5 0.3 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGR26925.1 - 4.4e-05 23.0 0.3 5.3e-05 22.8 0.3 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 EGR26925.1 - 0.13 11.8 0.5 0.26 10.7 0.1 1.7 2 1 0 2 2 2 0 Phosphoribosyl transferase Ras PF00071.22 EGR26926.1 - 4.1e-15 55.8 0.2 5.7e-15 55.3 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR26926.1 - 5.6e-14 52.4 0.7 9.9e-14 51.6 0.2 1.7 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_15 PF13175.6 EGR26926.1 - 1.9e-05 24.6 11.8 2.1e-05 24.4 11.8 1.1 1 0 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EGR26926.1 - 0.00013 22.5 0.1 0.00018 22.1 0.1 1.3 1 0 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 EGR26926.1 - 0.00017 21.6 0.0 0.00022 21.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 EGR26926.1 - 0.00052 20.4 0.8 0.00074 19.9 0.8 1.2 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 EGR26926.1 - 0.0015 19.0 0.0 0.0021 18.6 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EGR26926.1 - 0.0027 17.6 1.5 0.0044 16.9 1.5 1.5 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Arf PF00025.21 EGR26926.1 - 0.0057 16.1 0.3 0.0099 15.3 0.1 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_14 PF13173.6 EGR26926.1 - 0.0076 16.3 1.1 0.013 15.5 1.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGR26926.1 - 0.0077 16.6 0.0 0.0094 16.3 0.0 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGR26926.1 - 0.0091 16.3 0.0 0.012 15.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGR26926.1 - 0.011 15.7 0.2 0.018 14.9 0.1 1.4 1 1 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 EGR26926.1 - 0.021 14.6 0.2 0.039 13.7 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP-synt_ab PF00006.25 EGR26926.1 - 0.036 13.7 0.1 0.041 13.5 0.1 1.2 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.23 EGR26926.1 - 0.096 12.7 0.6 0.16 12.0 0.6 1.4 1 1 0 1 1 1 0 Dynamin family AAA_23 PF13476.6 EGR26926.1 - 0.18 12.3 9.3 0.45 11.0 9.3 1.8 1 1 0 1 1 1 0 AAA domain SMC_N PF02463.19 EGR26926.1 - 0.46 9.9 3.4 0.27 10.6 0.5 1.9 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain RabGAP-TBC PF00566.18 EGR26927.1 - 2.5e-20 73.1 7.1 2.5e-20 73.1 7.1 2.2 2 1 0 2 2 2 1 Rab-GTPase-TBC domain COX16 PF14138.6 EGR26927.1 - 0.36 11.4 4.4 6.5 7.4 0.5 2.5 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 Pkinase PF00069.25 EGR26929.1 - 1e-22 80.8 0.6 1.1e-22 80.7 0.6 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR26929.1 - 3.9e-12 46.0 0.1 4.5e-12 45.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR26929.1 - 1.6e-08 33.8 0.1 2.2e-08 33.3 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR26929.1 - 0.0013 18.2 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR26929.1 - 0.028 14.3 0.0 0.082 12.8 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family Band_7 PF01145.25 EGR26930.1 - 1.1e-31 110.2 1.5 1.5e-31 109.8 1.5 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EGR26930.1 - 0.0002 21.1 0.1 0.00032 20.5 0.1 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family Ras PF00071.22 EGR26932.1 - 4e-57 192.3 0.4 5.5e-57 191.9 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR26932.1 - 4.9e-36 123.6 0.0 9.3e-36 122.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR26932.1 - 4.6e-17 62.0 0.1 6e-17 61.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGR26932.1 - 2.4e-06 27.6 0.3 0.012 15.5 0.2 2.4 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGR26932.1 - 3.1e-06 27.3 0.0 5.1e-06 26.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGR26932.1 - 8.2e-06 25.5 0.1 2.9e-05 23.7 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGR26932.1 - 1.3e-05 24.7 0.3 1.7e-05 24.3 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EGR26932.1 - 0.00011 21.7 0.1 0.0029 17.2 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_15 PF13175.6 EGR26932.1 - 0.0035 17.1 1.1 0.0057 16.4 1.1 1.3 1 0 0 1 1 1 1 AAA ATPase domain SRPRB PF09439.10 EGR26932.1 - 0.0071 15.8 0.0 0.012 15.0 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EGR26932.1 - 0.043 13.5 0.7 0.77 9.5 0.7 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EGR26932.1 - 0.051 13.1 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Shisa PF13908.6 EGR26933.1 - 0.059 13.6 0.5 0.059 13.6 0.5 6.2 2 2 1 3 3 3 0 Wnt and FGF inhibitory regulator RCC1 PF00415.18 EGR26934.1 - 1e-37 128.5 6.3 2.4e-12 47.3 0.0 6.5 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR26934.1 - 2.4e-25 87.7 5.4 2.1e-07 30.5 0.1 5.1 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat PI3_PI4_kinase PF00454.27 EGR26934.1 - 1.2e-08 35.1 0.0 2.4e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Hira PF07569.11 EGR26934.1 - 1.1e-05 25.2 0.6 0.08 12.7 0.1 2.9 2 1 1 3 3 3 2 TUP1-like enhancer of split ubiquitin PF00240.23 EGR26934.1 - 0.00011 21.9 2.1 0.00011 21.9 2.1 2.4 2 0 0 2 2 2 1 Ubiquitin family Ubiquitin_2 PF14560.6 EGR26934.1 - 0.00043 20.7 1.9 0.0016 18.9 1.9 2.0 1 0 0 1 1 1 1 Ubiquitin-like domain RC-P840_PscD PF10657.9 EGR26934.1 - 0.014 15.5 0.2 0.014 15.5 0.2 2.4 3 0 0 3 3 3 0 Photosystem P840 reaction centre protein PscD WD40 PF00400.32 EGR26935.1 - 7.2e-07 29.8 0.0 0.00039 21.2 0.0 3.2 2 0 0 2 2 2 2 WD domain, G-beta repeat BH4 PF02180.17 EGR26935.1 - 0.053 13.4 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Bcl-2 homology region 4 Cript PF10235.9 EGR26935.1 - 1.2 9.8 3.8 7.8 7.1 1.3 2.5 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT WD40 PF00400.32 EGR26936.1 - 4.9e-12 46.2 2.5 0.0025 18.6 0.1 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR26936.1 - 1.4e-07 31.7 0.1 0.0001 22.6 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain AMP-binding PF00501.28 EGR26937.1 - 8.4e-66 222.3 0.0 1.1e-65 221.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Sigma54_CBD PF04963.13 EGR26937.1 - 0.005 16.7 0.2 0.016 15.1 0.2 1.8 1 0 0 1 1 1 1 Sigma-54 factor, core binding domain AMP-binding_C PF13193.6 EGR26937.1 - 0.23 12.5 0.0 0.42 11.6 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain YlmH_RBD PF17774.1 EGR26937.1 - 0.26 11.6 3.6 0.87 9.9 0.3 3.2 3 0 0 3 3 3 0 Putative RNA-binding domain in YlmH DUF1765 PF08578.10 EGR26937.1 - 0.97 9.9 6.4 0.74 10.3 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1765) Peptidase_M22 PF00814.25 EGR26938.1 - 2.4e-82 276.7 0.0 4.8e-82 275.7 0.0 1.4 1 1 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EGR26938.1 - 0.00018 21.3 0.2 0.00036 20.3 0.1 1.5 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus DASH_Spc34 PF08657.10 EGR26938.1 - 0.005 16.7 0.1 0.0066 16.3 0.1 1.2 1 0 0 1 1 1 1 DASH complex subunit Spc34 LCIB_C_CA PF18599.1 EGR26938.1 - 0.13 11.5 0.6 0.21 10.8 0.6 1.3 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases TTL PF03133.15 EGR26939.1 - 2.9e-53 180.9 2.4 4.6e-53 180.3 2.4 1.3 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR26939.1 - 0.00011 21.6 0.8 0.11 11.7 0.1 3.0 2 1 0 2 2 2 2 YheC/D like ATP-grasp Cro PF09048.10 EGR26939.1 - 0.017 15.1 0.2 0.082 13.0 0.4 2.0 2 0 0 2 2 2 0 Cro TTL PF03133.15 EGR26940.1 - 0.00012 21.3 3.0 0.00012 21.3 3.0 1.8 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family OGG_N PF07934.12 EGR26940.1 - 0.02 15.0 2.5 0.025 14.6 2.5 1.2 1 0 0 1 1 1 0 8-oxoguanine DNA glycosylase, N-terminal domain FliD_N PF02465.18 EGR26941.1 - 0.11 13.2 1.9 0.44 11.3 0.6 2.1 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Ubiquitin_2 PF14560.6 EGR26941.1 - 5.1 7.6 7.4 5.4 7.6 0.4 2.9 3 0 0 3 3 3 0 Ubiquitin-like domain Pkinase PF00069.25 EGR26942.1 - 2.8e-71 240.0 1.1 2.8e-71 240.0 1.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR26942.1 - 1.6e-44 152.1 0.1 2.5e-44 151.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR26942.1 - 5.5e-10 39.0 0.6 2.2e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EGR26942.1 - 0.009 14.8 0.0 0.019 13.8 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR26942.1 - 0.02 14.3 1.7 0.022 14.1 0.1 1.9 2 1 1 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family IMPDH PF00478.25 EGR26943.1 - 6.7e-143 475.9 1.7 8.4e-143 475.5 1.7 1.1 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain FMN_dh PF01070.18 EGR26943.1 - 2e-09 37.0 9.5 7.4e-08 31.8 9.9 2.9 2 1 0 2 2 2 1 FMN-dependent dehydrogenase NMO PF03060.15 EGR26943.1 - 1.1e-07 31.5 6.8 0.017 14.5 0.0 3.5 2 1 2 4 4 4 3 Nitronate monooxygenase CBS PF00571.28 EGR26943.1 - 2.3e-05 24.7 0.3 0.034 14.6 0.0 3.4 3 0 0 3 3 3 2 CBS domain ThiG PF05690.14 EGR26943.1 - 0.017 14.4 0.7 0.064 12.6 0.0 2.2 3 0 0 3 3 3 0 Thiazole biosynthesis protein ThiG Aldolase PF01081.19 EGR26943.1 - 0.086 12.2 4.4 0.052 13.0 0.6 2.5 3 0 0 3 3 3 0 KDPG and KHG aldolase PEP_mutase PF13714.6 EGR26943.1 - 0.097 12.1 0.4 0.82 9.1 0.1 2.3 2 0 0 2 2 2 0 Phosphoenolpyruvate phosphomutase Pkinase PF00069.25 EGR26944.1 - 3.9e-71 239.5 1.0 3.9e-71 239.5 1.0 7.1 4 2 4 9 9 9 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR26944.1 - 1.8e-43 148.7 0.1 1.8e-43 148.7 0.1 3.4 3 0 0 3 3 3 1 Protein tyrosine kinase zf-MYND PF01753.18 EGR26944.1 - 1.3e-05 25.2 9.7 2.9e-05 24.1 9.7 1.6 1 0 0 1 1 1 1 MYND finger APH PF01636.23 EGR26944.1 - 0.21 11.5 0.0 0.21 11.5 0.0 2.0 3 0 0 3 3 3 0 Phosphotransferase enzyme family EMC3_TMCO1 PF01956.16 EGR26945.1 - 1.6e-36 125.6 5.0 1.9e-36 125.3 5.0 1.1 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like tRNA-synt_1 PF00133.22 EGR26946.1 - 1.6e-21 76.2 2.7 2.3e-20 72.4 2.7 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGR26946.1 - 3e-10 40.3 1.1 7.7e-10 38.9 1.1 1.8 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGR26946.1 - 2.3e-09 36.5 1.0 4.8e-09 35.5 0.3 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EGR26946.1 - 2.6e-07 30.3 1.8 3e-07 30.1 0.1 2.0 2 1 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain Ribosomal_60s PF00428.19 EGR26948.1 - 3e-14 53.4 7.3 4.4e-14 52.8 7.3 1.2 1 0 0 1 1 1 1 60s Acidic ribosomal protein FAD-SLDH PF12318.8 EGR26948.1 - 0.13 12.4 0.2 0.24 11.5 0.1 1.4 1 1 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase Phage_holin_6_1 PF09682.10 EGR26948.1 - 0.22 12.0 3.7 2.3 8.7 0.1 2.2 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Tim29 PF10171.9 EGR26949.1 - 0.14 11.6 5.1 0.17 11.4 5.1 1.0 1 0 0 1 1 1 0 Translocase of the Inner Mitochondrial membrane 29 AdenylateSensor PF16579.5 EGR26949.1 - 0.29 11.6 4.9 0.46 11.0 4.9 1.3 1 1 0 1 1 1 0 Adenylate sensor of SNF1-like protein kinase YfzA PF14118.6 EGR26950.1 - 0.31 11.5 7.2 0.74 10.2 3.3 2.7 1 1 1 2 2 2 0 YfzA-like protein DUF3641 PF12345.8 EGR26950.1 - 9.3 6.3 7.1 1.9 8.5 3.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3641) PAPA-1 PF04795.12 EGR26951.1 - 5.7e-13 49.5 11.4 5.7e-13 49.5 11.4 4.0 3 2 0 3 3 3 1 PAPA-1-like conserved region Zip PF02535.22 EGR26952.1 - 3.3e-41 141.6 11.5 3.3e-41 141.6 11.5 2.9 2 1 0 2 2 2 1 ZIP Zinc transporter DUF999 PF06198.11 EGR26952.1 - 0.0082 16.2 0.1 0.029 14.4 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF999) Bap31 PF05529.12 EGR26952.1 - 0.009 15.9 0.0 0.094 12.6 0.0 2.5 2 0 0 2 2 2 1 Bap31/Bap29 transmembrane region Tim54 PF11711.8 EGR26952.1 - 0.019 13.8 2.0 0.15 10.8 0.0 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 EmrE PF13536.6 EGR26952.1 - 0.02 14.5 4.8 0.27 10.8 0.2 2.9 2 1 1 3 3 3 0 Putative multidrug resistance efflux transporter TMEM144 PF07857.12 EGR26952.1 - 0.034 13.1 3.4 0.41 9.5 3.3 2.4 1 1 0 1 1 1 0 Transmembrane family, TMEM144 of transporters Serinc PF03348.15 EGR26952.1 - 0.43 9.5 2.9 12 4.7 0.0 2.6 3 0 0 3 3 3 0 Serine incorporator (Serinc) CPSF73-100_C PF11718.8 EGR26952.1 - 0.93 9.0 5.0 2.2 7.8 1.3 2.3 2 0 0 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term DUF4271 PF14093.6 EGR26952.1 - 1.6 8.6 12.8 0.92 9.4 1.2 3.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4271) DUF3671 PF12420.8 EGR26952.1 - 5.4 7.1 12.4 1.4 9.0 1.4 3.8 3 1 0 3 3 3 0 Protein of unknown function Ribosomal_S28e PF01200.18 EGR26954.1 - 1.2e-28 98.8 4.2 1.4e-28 98.7 4.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Fe_hyd_lg_C PF02906.14 EGR26954.1 - 0.14 11.8 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain Fimbrial_K88 PF02432.15 EGR26954.1 - 0.18 11.8 0.2 0.2 11.6 0.2 1.1 1 0 0 1 1 1 0 Fimbrial, major and minor subunit Zip PF02535.22 EGR26955.1 - 6.2 5.9 6.5 8.6 5.5 6.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PEP-utilisers_N PF05524.13 EGR26955.1 - 7.9 6.7 13.3 0.52 10.5 0.1 2.8 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal CrtC PF07143.11 EGR26956.1 - 3.2 8.4 15.5 3.3 8.4 12.2 2.5 2 1 0 2 2 2 0 CrtC N-terminal lipocalin domain Kinesin PF00225.23 EGR26957.1 - 1.4e-60 205.0 5.9 1.6e-60 204.8 5.9 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR26957.1 - 0.00016 21.6 2.0 0.0002 21.3 0.4 1.9 2 0 0 2 2 2 1 Microtubule binding EIIA-man PF03610.16 EGR26957.1 - 0.15 12.3 0.1 0.39 11.0 0.1 1.7 1 1 0 1 1 1 0 PTS system fructose IIA component Pepdidase_M14_N PF18027.1 EGR26958.1 - 8.6e-14 51.8 2.3 2e-13 50.6 2.3 1.7 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 EGR26958.1 - 4.2e-13 49.7 0.6 3.3e-12 46.8 0.0 2.6 1 1 1 2 2 2 1 Zinc carboxypeptidase AstE_AspA PF04952.14 EGR26958.1 - 0.004 16.3 0.0 0.0062 15.7 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family HMG_box PF00505.19 EGR26959.1 - 0.00082 19.7 1.6 0.0033 17.8 1.6 2.1 1 0 0 1 1 1 1 HMG (high mobility group) box Dus PF01207.17 EGR26961.1 - 1.7e-77 260.5 0.0 2.3e-77 260.1 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EGR26961.1 - 2.8e-11 43.3 0.0 8.8e-06 25.3 0.0 2.0 1 1 1 2 2 2 2 Histidine biosynthesis protein SOR_SNZ PF01680.17 EGR26961.1 - 3.9e-05 23.5 0.1 0.0031 17.3 0.0 2.2 1 1 1 2 2 2 1 SOR/SNZ family TMP-TENI PF02581.17 EGR26961.1 - 0.00023 20.5 0.0 0.00054 19.4 0.0 1.7 1 0 0 1 1 1 1 Thiamine monophosphate synthase ThiG PF05690.14 EGR26961.1 - 0.00027 20.3 0.0 0.00045 19.6 0.0 1.2 1 0 0 1 1 1 1 Thiazole biosynthesis protein ThiG FMN_dh PF01070.18 EGR26961.1 - 0.0023 17.0 0.0 0.27 10.2 0.0 2.3 1 1 1 2 2 2 2 FMN-dependent dehydrogenase NMO PF03060.15 EGR26961.1 - 0.016 14.7 0.0 0.038 13.4 0.0 1.5 1 1 0 1 1 1 0 Nitronate monooxygenase DHO_dh PF01180.21 EGR26961.1 - 0.045 12.9 0.0 1.2 8.3 0.0 2.3 1 1 0 1 1 1 0 Dihydroorotate dehydrogenase PA28_alpha PF02251.18 EGR26961.1 - 0.078 13.0 0.6 0.2 11.7 0.1 2.0 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit G3P_antiterm PF04309.12 EGR26961.1 - 0.1 12.0 0.0 0.33 10.4 0.0 1.8 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Pkinase PF00069.25 EGR26963.1 - 2.9e-69 233.4 0.0 4e-69 232.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR26963.1 - 2.7e-37 128.5 0.0 3.8e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR26963.1 - 1.6e-07 30.6 2.1 2.7e-07 29.9 2.1 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGR26963.1 - 2.1e-05 24.0 0.0 5.1e-05 22.7 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR26963.1 - 0.003 17.0 0.1 0.0053 16.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR26963.1 - 0.017 15.1 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EGR26963.1 - 0.02 14.5 0.5 0.077 12.6 0.1 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Myb_DNA-bind_5 PF13873.6 EGR26963.1 - 0.1 12.7 1.4 0.26 11.4 0.1 2.2 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Pkinase PF00069.25 EGR26964.1 - 2.4e-64 217.2 0.1 4e-64 216.5 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR26964.1 - 2e-32 112.5 0.0 2.9e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR26964.1 - 0.00013 21.4 0.0 0.00096 18.5 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR26964.1 - 0.00074 18.4 0.0 0.0016 17.3 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR26964.1 - 0.022 14.7 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EGR26964.1 - 0.64 9.6 4.5 4.1 7.0 0.6 2.8 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Mito_carr PF00153.27 EGR26965.1 - 6.7e-50 167.0 3.2 1e-22 79.8 0.2 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Dynein_C PF18199.1 EGR26966.1 - 3.2e-102 341.9 0.1 3.6e-102 341.7 0.1 1.0 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain Ras PF00071.22 EGR26967.1 - 2.8e-22 79.1 1.0 2.7e-20 72.6 1.0 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGR26967.1 - 8.1e-15 55.1 0.9 1.2e-06 28.8 0.1 2.2 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Abi_2 PF07751.11 EGR26967.1 - 0.0025 18.1 1.4 0.0028 18.0 1.4 1.1 1 0 0 1 1 1 1 Abi-like protein STAS PF01740.21 EGR26967.1 - 0.052 13.2 0.5 2.3 7.9 0.4 2.1 1 1 1 2 2 2 0 STAS domain Ion_trans_2 PF07885.16 EGR26968.1 - 1.5e-09 37.7 12.3 1.5e-09 37.7 12.3 2.6 2 1 0 2 2 2 1 Ion channel Saf_2TM PF18303.1 EGR26968.1 - 4.4 6.9 13.1 0.23 11.0 0.6 3.1 3 1 1 4 4 4 0 SAVED-fused 2TM effector domain GST_N PF02798.20 EGR26969.1 - 1.9e-17 63.3 0.2 4.3e-17 62.2 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGR26969.1 - 2.2e-17 63.2 0.2 5.8e-17 61.9 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGR26969.1 - 3.1e-15 56.2 0.0 6.4e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGR26969.1 - 2.2e-10 40.6 0.0 4.1e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGR26969.1 - 6.2e-08 32.5 0.0 2.6e-07 30.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGR26969.1 - 2.8e-07 30.6 0.0 6.1e-07 29.6 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGR26969.1 - 0.00023 21.9 0.0 0.0013 19.4 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 EGR26969.1 - 0.0037 17.5 0.0 0.0078 16.5 0.0 1.6 1 1 0 1 1 1 1 Outer mitochondrial membrane transport complex protein Sugar_tr PF00083.24 EGR26970.1 - 2.7e-08 33.1 18.7 9.6e-06 24.7 10.5 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGR26970.1 - 4.6e-07 29.1 12.3 4.6e-07 29.1 12.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily NIF PF03031.18 EGR26971.1 - 1.2e-28 99.8 0.7 3.3e-28 98.4 0.2 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase DUF1794 PF08768.11 EGR26971.1 - 0.026 14.5 0.0 0.04 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1794) Put_Phosphatase PF06888.12 EGR26971.1 - 0.038 13.4 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative Phosphatase Stealth_CR2 PF11380.8 EGR26971.1 - 0.062 13.5 0.1 1.6 9.0 0.0 2.4 2 0 0 2 2 2 0 Stealth protein CR2, conserved region 2 Ion_trans PF00520.31 EGR26972.1 - 2.4e-28 99.0 13.9 2.8e-28 98.8 13.9 1.1 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGR26972.1 - 1.4e-08 34.6 1.2 1.4e-08 34.6 1.2 3.1 2 2 2 4 4 4 1 Ion channel MMR_HSR1 PF01926.23 EGR26973.1 - 1.6e-13 50.7 0.0 8.7e-13 48.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGR26973.1 - 8.6e-12 45.3 0.0 1.5e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 EGR26973.1 - 1.8e-06 27.5 0.1 0.00097 18.7 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B Ras PF00071.22 EGR26973.1 - 0.00021 20.9 1.5 0.0036 16.9 0.1 2.5 3 0 0 3 3 3 1 Ras family AAA_18 PF13238.6 EGR26973.1 - 0.00027 21.5 0.0 0.0011 19.5 0.0 1.9 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 EGR26973.1 - 0.0044 16.6 0.1 1.7 8.1 0.0 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EGR26973.1 - 0.0064 16.6 2.0 1.2 9.2 0.1 2.6 2 1 1 3 3 3 2 Dynamin family IIGP PF05049.13 EGR26973.1 - 0.011 14.8 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AIG1 PF04548.16 EGR26973.1 - 0.012 14.9 0.5 0.02 14.2 0.0 1.6 2 0 0 2 2 2 0 AIG1 family RNA_helicase PF00910.22 EGR26973.1 - 0.013 15.9 1.1 0.2 12.0 0.0 2.7 3 0 0 3 3 3 0 RNA helicase MMR_HSR1_Xtn PF16897.5 EGR26973.1 - 0.017 15.1 2.4 0.022 14.7 0.2 2.2 2 0 0 2 2 2 0 C-terminal region of MMR_HSR1 domain KTI12 PF08433.10 EGR26973.1 - 0.02 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Roc PF08477.13 EGR26973.1 - 0.027 14.7 0.0 0.73 10.1 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 EGR26973.1 - 0.044 12.8 0.0 0.073 12.0 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 EGR26973.1 - 0.064 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGR26973.1 - 0.096 11.8 9.1 0.076 12.2 1.5 2.7 1 1 1 2 2 2 0 G-protein alpha subunit CDC73_C PF05179.14 EGR26974.1 - 7.2e-41 139.5 0.6 1e-40 139.0 0.6 1.2 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal NIF PF03031.18 EGR26975.1 - 3.6e-51 173.0 0.2 3.6e-51 173.0 0.2 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase DUF1653 PF07866.11 EGR26975.1 - 0.13 12.6 0.1 0.35 11.2 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1653) Connexin PF00029.19 EGR26975.1 - 0.17 11.6 1.2 0.26 11.0 1.2 1.2 1 0 0 1 1 1 0 Connexin Porph_ging PF09697.10 EGR26975.1 - 0.18 12.3 1.7 0.8 10.3 1.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) OAD_gamma PF04277.13 EGR26975.1 - 0.51 11.0 4.3 2.2 8.9 4.3 2.1 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain ParcG PF10274.9 EGR26976.1 - 2.2e-54 184.4 0.3 2.2e-54 184.4 0.3 2.2 3 0 0 3 3 3 1 Parkin co-regulated protein HTH_38 PF13936.6 EGR26976.1 - 0.03 14.1 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_7 PF02796.15 EGR26976.1 - 0.096 12.8 0.0 0.39 10.8 0.0 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain of resolvase Helicase_C PF00271.31 EGR26977.1 - 1.6e-23 83.2 15.2 6.7e-23 81.2 0.3 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain DEAD PF00270.29 EGR26977.1 - 2.5e-22 79.5 2.9 1e-21 77.5 0.3 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EGR26977.1 - 5.2e-05 23.3 22.9 7.5e-05 22.8 17.6 2.8 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_2 PF13307.6 EGR26977.1 - 0.0023 18.1 5.3 0.0049 17.1 0.2 2.5 1 1 1 2 2 2 1 Helicase C-terminal domain AAA_19 PF13245.6 EGR26977.1 - 0.0089 16.4 0.0 0.018 15.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EGR26977.1 - 0.0096 15.4 0.1 0.019 14.4 0.1 1.5 1 0 0 1 1 1 1 PhoH-like protein Helicase_RecD PF05127.14 EGR26977.1 - 0.029 14.2 5.3 1.2 8.9 0.0 3.1 2 1 1 3 3 3 0 Helicase DUF2620 PF10941.8 EGR26977.1 - 0.14 12.3 0.1 1.4 9.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function DUF2620 WD40 PF00400.32 EGR26978.1 - 7.1e-24 83.6 7.0 3.5e-09 37.1 0.0 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR26978.1 - 0.00016 21.9 0.1 0.16 12.3 0.0 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain STE PF02200.16 EGR26978.1 - 0.06 13.8 0.5 2.5 8.5 0.0 2.8 2 0 0 2 2 2 0 STE like transcription factor Piezo_RRas_bdg PF12166.8 EGR26980.1 - 1.1e-97 328.1 9.6 1.1e-97 328.1 9.6 1.9 2 0 0 2 2 2 1 Piezo non-specific cation channel, R-Ras-binding domain DcrB PF08786.11 EGR26980.1 - 0.11 12.6 1.0 0.37 10.9 0.7 2.0 2 0 0 2 2 2 0 DcrB Binary_toxB_3 PF17476.2 EGR26980.1 - 6.2 7.1 9.9 0.24 11.6 1.3 2.4 2 0 0 2 2 2 0 Clostridial binary toxin B/anthrax toxin PA domain 3 Cytokin_check_N PF10407.9 EGR26982.1 - 7.9e-06 25.7 0.2 1.4e-05 24.9 0.2 1.4 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus cNMP_binding PF00027.29 EGR26984.1 - 1.8e-16 60.0 0.0 3e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 EGR26984.1 - 2.9e-16 59.4 20.4 2.9e-16 59.4 20.4 2.3 2 1 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 EGR26984.1 - 2e-10 40.5 16.8 2.5e-09 37.0 16.8 2.3 1 1 0 1 1 1 1 Ion channel C2 PF00168.30 EGR26984.1 - 0.015 15.6 0.1 0.035 14.4 0.1 1.6 1 0 0 1 1 1 0 C2 domain Lig_chan PF00060.26 EGR26984.1 - 0.017 15.0 0.0 0.028 14.3 0.0 1.7 1 1 0 1 1 1 0 Ligand-gated ion channel DUF2975 PF11188.8 EGR26984.1 - 0.55 10.1 6.7 2.1 8.2 6.7 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2975) RecX PF02631.16 EGR26984.1 - 2 8.9 9.6 1.5 9.3 0.1 2.7 2 0 0 2 2 2 0 RecX family DUF5402 PF17393.2 EGR26985.1 - 0.021 14.7 1.9 0.17 11.8 0.4 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5402) Hydrolase PF00702.26 EGR26985.1 - 0.025 14.9 0.7 0.35 11.1 0.7 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Lipase_GDSL PF00657.22 EGR26985.1 - 0.031 14.2 1.2 0.058 13.4 0.2 1.9 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase DUF2203 PF09969.9 EGR26985.1 - 0.084 13.6 5.7 11 6.8 0.5 3.5 2 2 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF29 PF01724.16 EGR26985.1 - 0.36 11.0 6.2 8 6.7 0.0 3.4 3 1 0 3 3 3 0 Domain of unknown function DUF29 DUF948 PF06103.11 EGR26985.1 - 1.2 9.5 13.2 6.3 7.1 0.4 4.4 3 2 0 3 3 3 0 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.21 EGR26985.1 - 3.8 7.3 12.5 0.33 10.7 1.4 3.3 2 2 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ZZ PF00569.17 EGR26986.1 - 6.2e-14 51.5 7.0 1.3e-13 50.5 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type YbjQ_1 PF01906.17 EGR26986.1 - 0.0032 18.1 0.3 1.2 9.9 0.0 3.9 3 0 0 3 3 3 1 Putative heavy-metal-binding zf-UBR PF02207.20 EGR26986.1 - 0.068 13.3 2.8 0.2 11.9 2.8 1.7 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Peptidase_M8 PF01457.16 EGR26987.1 - 3.2e-39 135.0 11.3 9.1e-32 110.4 0.1 2.3 1 1 1 2 2 2 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR26987.1 - 0.0078 16.2 9.8 0.0078 16.2 9.8 2.8 2 0 0 2 2 2 1 Tenascin EGF domain Ephrin_rec_like PF07699.13 EGR26989.1 - 0.00036 20.3 14.7 0.0016 18.2 3.2 11.6 9 5 3 12 12 12 6 Putative ephrin-receptor like Fer4_9 PF13187.6 EGR26989.1 - 0.0012 18.9 55.3 0.48 10.6 2.3 8.5 3 3 2 5 5 5 3 4Fe-4S dicluster domain VirK PF06903.12 EGR26989.1 - 0.0068 16.5 8.9 28 4.9 0.0 4.9 4 0 0 4 4 4 2 VirK protein Antistasin PF02822.14 EGR26989.1 - 0.041 14.5 11.4 4.8 7.9 0.1 7.3 8 0 0 8 8 8 0 Antistasin family CBM_5_12 PF02839.14 EGR26989.1 - 3.7 8.3 10.5 80 4.1 0.1 4.6 4 0 0 4 4 4 0 Carbohydrate binding domain Ephrin_rec_like PF07699.13 EGR26990.1 - 0.0092 15.7 21.9 0.032 14.0 4.0 3.8 2 1 2 4 4 4 2 Putative ephrin-receptor like NMD3 PF04981.13 EGR26990.1 - 0.99 8.8 6.9 0.85 9.0 1.7 2.2 1 1 1 2 2 2 0 NMD3 family GF_recep_IV PF14843.6 EGR26990.1 - 3.2 7.6 12.0 6.4 6.6 9.4 2.7 1 1 1 2 2 2 0 Growth factor receptor domain IV AMP-binding PF00501.28 EGR26991.1 - 7.5e-73 245.5 0.0 1e-72 245.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGR26991.1 - 1.7e-05 25.7 0.0 3.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FUN14 PF04930.15 EGR26992.1 - 5e-30 103.8 0.1 5.7e-29 100.4 0.1 2.0 1 1 0 1 1 1 1 FUN14 family EF-hand_5 PF13202.6 EGR26992.1 - 9e-08 31.3 9.1 0.018 14.5 0.0 3.5 2 1 1 3 3 3 3 EF hand EF-hand_1 PF00036.32 EGR26992.1 - 4e-07 29.1 10.5 0.044 13.3 0.2 3.8 2 1 2 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGR26992.1 - 8.5e-07 28.4 9.5 0.088 12.8 0.3 3.9 2 1 2 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EGR26992.1 - 2.9e-06 27.6 7.1 0.33 11.4 0.1 3.4 1 1 2 3 3 3 3 EF-hand domain pair Dockerin_1 PF00404.18 EGR26992.1 - 5.4e-05 23.3 6.9 0.022 14.9 0.1 3.1 1 1 1 2 2 2 1 Dockerin type I domain EF-hand_8 PF13833.6 EGR26992.1 - 0.0002 21.1 6.3 0.47 10.3 0.0 3.5 3 1 1 4 4 4 2 EF-hand domain pair DUF2987 PF11205.8 EGR26992.1 - 0.053 13.4 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2987) Nodulin-like PF06813.13 EGR26992.1 - 0.094 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Nodulin-like LPAM_1 PF08139.12 EGR26993.1 - 0.35 11.5 1.9 0.61 10.7 1.9 1.3 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site Pap_E4 PF02711.14 EGR26993.1 - 0.61 11.1 8.4 0.1 13.6 2.8 2.2 2 1 0 2 2 2 0 E4 protein MqsR_toxin PF15723.5 EGR26994.1 - 0.0056 17.0 5.3 29 5.1 0.1 5.1 4 0 0 4 4 4 2 Motility quorum-sensing regulator, toxin of MqsA TA0956 PF11513.8 EGR26994.1 - 0.087 13.1 2.6 11 6.3 0.0 4.5 5 0 0 5 5 5 0 Thermoplasma acidophilum protein TA0956 Casc1_N PF15927.5 EGR26994.1 - 0.23 11.1 6.1 33 4.1 0.0 3.9 5 0 0 5 5 5 0 Cancer susceptibility candidate 1 N-terminus AGTRAP PF06396.11 EGR26994.1 - 1.1 9.0 3.9 63 3.3 0.0 4.7 5 0 0 5 5 5 0 Angiotensin II, type I receptor-associated protein (AGTRAP) DEAD PF00270.29 EGR26997.1 - 9.1e-48 162.3 0.1 2.2e-47 161.1 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR26997.1 - 1.8e-32 112.0 1.1 2.1e-30 105.3 0.0 3.8 4 0 0 4 4 4 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGR26997.1 - 0.01 16.1 0.0 0.031 14.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGR26997.1 - 1.9 8.9 5.2 2 8.9 0.1 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF4490 PF14892.6 EGR26998.1 - 1.8e-17 63.3 10.2 1.6e-15 57.0 4.8 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF4490) Sec8_exocyst PF04048.14 EGR26998.1 - 0.041 13.8 0.6 0.062 13.2 0.6 1.2 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Clathrin PF00637.20 EGR26999.1 - 2.5e-14 53.4 33.8 1.3e-12 47.8 8.7 3.3 3 0 0 3 3 3 2 Region in Clathrin and VPS Vps39_2 PF10367.9 EGR26999.1 - 0.0001 22.7 2.2 0.0001 22.7 2.2 3.6 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 2 VPS11_C PF12451.8 EGR26999.1 - 0.00043 20.5 1.3 0.00043 20.5 1.3 3.6 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-rbx1 PF12678.7 EGR26999.1 - 0.016 15.5 4.5 0.016 15.5 4.5 2.2 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3H2C3 PF17122.5 EGR26999.1 - 0.024 14.6 9.2 0.025 14.6 6.2 2.3 2 0 0 2 2 2 0 Zinc-finger zf-RING_UBOX PF13445.6 EGR26999.1 - 0.032 14.3 7.0 0.095 12.7 7.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGR26999.1 - 0.094 12.6 7.8 0.24 11.3 7.8 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGR26999.1 - 0.1 12.5 6.4 0.29 11.0 6.4 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGR26999.1 - 0.27 10.9 7.3 4.7 6.9 4.3 2.4 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EGR26999.1 - 0.65 10.0 7.4 1.8 8.6 7.4 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_2 PF13639.6 EGR26999.1 - 0.65 10.4 10.0 0.42 11.0 6.8 2.2 2 0 0 2 2 2 0 Ring finger domain Ribosomal_L28e PF01778.17 EGR27001.1 - 1.1e-33 116.4 3.3 1.1e-33 116.4 3.3 3.2 2 1 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 EGR27001.1 - 8.7e-26 90.4 18.1 8.7e-26 90.4 18.1 2.6 1 1 1 2 2 2 1 Mak16 protein C-terminal region ILEI PF15711.5 EGR27002.1 - 0.45 11.0 3.6 2.1 8.9 0.3 3.2 2 1 0 2 2 2 0 Interleukin-like EMT inducer LCM PF04072.14 EGR27003.1 - 1.1e-21 77.6 0.0 6e-21 75.2 0.0 1.9 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase RST PF12174.8 EGR27003.1 - 6.2 6.8 7.1 8.6 6.4 0.1 3.3 2 1 1 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain Ferrochelatase PF00762.19 EGR27005.1 - 1.7e-82 277.1 0.0 2e-82 276.8 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase DUF4845 PF16137.5 EGR27005.1 - 0.034 15.0 0.1 0.084 13.7 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4845) DUF2971 PF11185.8 EGR27005.1 - 3.7 8.8 6.1 9.5 7.5 0.4 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2971) Pkinase PF00069.25 EGR27006.1 - 1.3e-16 60.8 0.1 1.5e-16 60.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGR27006.1 - 2.9e-08 32.9 0.1 4.5e-08 32.3 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 EGR27006.1 - 8e-08 31.9 0.0 1e-07 31.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR27006.1 - 0.0016 18.4 0.0 0.0025 17.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-HC5HC2H_2 PF13832.6 EGR27007.1 - 1.3e-18 67.1 12.7 1.3e-18 67.1 12.7 4.1 4 2 1 5 5 5 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EGR27007.1 - 1.3e-17 63.8 11.7 1.3e-17 63.8 11.7 4.5 4 1 0 4 4 4 2 PHD-like zinc-binding domain PHD PF00628.29 EGR27007.1 - 2.3e-10 40.2 33.5 2e-09 37.2 7.6 3.8 3 0 0 3 3 3 2 PHD-finger Zf_RING PF16744.5 EGR27007.1 - 8.2 6.6 18.8 0.65 10.1 4.4 3.3 3 0 0 3 3 3 0 KIAA1045 RING finger zf-RING_2 PF13639.6 EGR27007.1 - 9.1 6.7 30.1 0.16 12.3 5.5 3.4 3 0 0 3 3 3 0 Ring finger domain MORN PF02493.20 EGR27008.1 - 9.9e-26 88.1 55.2 0.00013 21.6 0.1 10.3 10 0 0 10 10 10 9 MORN repeat AcylCoA_dehyd_C PF12186.8 EGR27008.1 - 3.6 7.8 7.8 4.9 7.3 0.6 2.8 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal Kelch_4 PF13418.6 EGR27009.1 - 6.2e-40 135.0 4.5 3.6e-10 39.7 0.0 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EGR27009.1 - 1.1e-29 101.7 9.6 8.3e-09 35.4 0.0 7.0 7 1 1 8 8 8 5 Kelch motif Kelch_1 PF01344.25 EGR27009.1 - 1.1e-27 95.3 1.8 5.3e-06 25.9 0.0 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 EGR27009.1 - 1.7e-26 91.9 0.0 5.2e-08 33.0 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EGR27009.1 - 1.4e-23 82.4 1.9 0.00063 19.7 0.0 6.8 7 0 0 7 7 7 6 Kelch motif Kelch_2 PF07646.15 EGR27009.1 - 7.5e-17 60.6 4.9 4.6e-06 26.4 0.0 6.3 6 1 0 6 6 6 4 Kelch motif HATPase_c_3 PF13589.6 EGR27009.1 - 0.0036 17.1 0.1 0.039 13.8 0.0 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_S19e PF01090.19 EGR27010.1 - 3.9e-39 133.5 0.2 5.6e-39 133.0 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S19e Yip1 PF04893.17 EGR27010.1 - 1.7e-09 37.6 9.4 3.4e-09 36.7 8.3 1.8 1 1 1 2 2 2 1 Yip1 domain Cas_CXXC_CXXC PF09706.10 EGR27010.1 - 0.028 14.7 0.9 0.088 13.1 0.9 1.8 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) Spore_YhaL PF14147.6 EGR27010.1 - 0.18 11.5 3.6 3.2 7.5 0.1 3.5 4 0 0 4 4 4 0 Sporulation protein YhaL DUF3975 PF13126.6 EGR27010.1 - 0.88 10.1 8.5 0.32 11.5 2.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3975) Ribosomal_S13_N PF08069.12 EGR27011.1 - 4.5e-27 93.9 1.6 6.6e-27 93.3 1.0 1.6 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EGR27011.1 - 6.5e-15 55.1 0.5 9.6e-15 54.6 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 MFS_1 PF07690.16 EGR27012.1 - 0.0013 17.7 0.1 0.0014 17.6 0.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Methyltransf_3 PF01596.17 EGR27012.1 - 0.029 13.5 0.0 0.034 13.3 0.0 1.1 1 0 0 1 1 1 0 O-methyltransferase DSPc PF00782.20 EGR27013.1 - 6.5e-22 77.8 5.2 6.5e-22 77.8 5.2 4.0 2 1 1 3 3 3 1 Dual specificity phosphatase, catalytic domain Gelsolin PF00626.22 EGR27013.1 - 6.4e-09 35.6 1.6 0.00044 20.1 0.1 2.9 2 0 0 2 2 2 2 Gelsolin repeat Ribonuc_red_sm PF00268.21 EGR27014.1 - 5.1e-117 390.3 8.0 6.4e-117 390.0 8.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 EGR27014.1 - 0.072 13.9 0.0 0.19 12.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) Peptidase_C26 PF07722.13 EGR27015.1 - 8.8e-09 35.4 0.0 2.2e-08 34.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 EGR27015.1 - 0.0019 18.0 0.0 0.0024 17.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 EGR27015.1 - 0.073 12.9 0.0 0.089 12.6 0.0 1.3 1 0 0 1 1 1 0 SNO glutamine amidotransferase family DUF1906 PF08924.11 EGR27015.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1906) AAA PF00004.29 EGR27016.1 - 4.3e-44 150.1 0.0 8.2e-44 149.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGR27016.1 - 1.8e-22 78.9 0.1 3.4e-13 49.1 0.1 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_2 PF07724.14 EGR27016.1 - 3.7e-06 27.2 0.0 8.8e-06 25.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGR27016.1 - 1.7e-05 24.6 0.0 0.00017 21.4 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGR27016.1 - 5.4e-05 23.2 0.0 0.00018 21.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EGR27016.1 - 0.0001 21.7 0.1 0.00025 20.4 0.0 1.6 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_16 PF13191.6 EGR27016.1 - 0.00079 19.8 0.1 0.23 11.8 0.0 3.0 2 1 1 3 3 3 1 AAA ATPase domain Vps4_C PF09336.10 EGR27016.1 - 0.0047 16.9 0.1 0.036 14.1 0.0 2.4 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Rad17 PF03215.15 EGR27016.1 - 0.0098 15.8 0.1 0.036 14.0 0.0 1.9 1 1 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 EGR27016.1 - 0.016 14.6 0.1 0.031 13.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EGR27016.1 - 0.019 15.3 0.0 0.056 13.8 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Parvo_NS1 PF01057.17 EGR27016.1 - 0.071 12.2 0.1 0.68 9.0 0.0 2.1 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 DUF815 PF05673.13 EGR27016.1 - 0.11 11.7 0.0 0.21 10.7 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 EGR27016.1 - 0.12 12.1 0.1 0.38 10.5 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_14 PF13173.6 EGR27016.1 - 0.12 12.4 0.0 0.41 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGR27016.1 - 0.22 11.8 0.4 5.2 7.3 0.0 2.6 2 1 1 3 3 3 0 AAA domain Kelch_1 PF01344.25 EGR27017.1 - 3.4e-37 125.8 9.0 3.3e-08 33.0 0.2 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EGR27017.1 - 3.3e-36 122.9 0.8 9.4e-08 32.2 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EGR27017.1 - 9.8e-31 105.0 18.6 5e-08 33.0 0.0 6.3 4 1 2 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EGR27017.1 - 4.2e-29 99.4 14.0 4.6e-06 26.4 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGR27017.1 - 7.1e-29 99.6 19.4 1.5e-09 37.7 0.0 7.0 4 2 3 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.6 EGR27017.1 - 5.2e-28 96.5 19.8 0.00061 19.7 0.1 6.7 6 1 1 7 7 7 6 Kelch motif BTB PF00651.31 EGR27017.1 - 2.8e-21 75.8 2.6 6.1e-21 74.7 0.4 2.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.15 EGR27017.1 - 0.0034 17.5 0.4 0.012 15.7 0.1 2.0 2 0 0 2 2 2 1 BTB And C-terminal Kelch RAG2 PF03089.14 EGR27017.1 - 0.01 14.8 0.0 4.6 6.1 0.0 2.9 3 0 0 3 3 3 0 Recombination activating protein 2 AhpC-TSA PF00578.21 EGR27018.1 - 2.4e-34 117.9 0.0 5.5e-34 116.7 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 EGR27018.1 - 3.9e-16 59.1 0.0 4.8e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EGR27018.1 - 5.1e-06 26.2 0.3 8.8e-06 25.5 0.3 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin GTP_EFTU PF00009.27 EGR27019.1 - 6.3e-38 130.3 0.0 7e-38 130.1 0.0 1.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGR27019.1 - 0.00091 19.3 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGR27019.1 - 0.0026 17.3 0.0 0.0095 15.5 0.0 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AIG1 PF04548.16 EGR27019.1 - 0.018 14.4 0.0 0.026 13.8 0.0 1.4 2 0 0 2 2 2 0 AIG1 family Pil1 PF13805.6 EGR27019.1 - 0.064 12.7 0.0 0.085 12.3 0.0 1.1 1 0 0 1 1 1 0 Eisosome component PIL1 EFG_IV PF03764.18 EGR27020.1 - 3.4e-35 120.4 0.1 2.2e-34 117.8 0.1 2.3 2 1 1 3 3 3 1 Elongation factor G, domain IV EFG_II PF14492.6 EGR27020.1 - 3.2e-30 104.1 0.0 6.2e-30 103.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EGR27020.1 - 1.4e-24 85.9 0.1 2.6e-24 85.0 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGR27020.1 - 1.6e-14 54.1 0.0 4e-14 52.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EGR27020.1 - 5.2e-06 26.3 0.1 1.5e-05 24.9 0.0 1.7 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain PDEase_I PF00233.19 EGR27021.1 - 7.8e-80 268.0 6.9 7.8e-80 268.0 6.9 2.2 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase TSA PF03249.13 EGR27021.1 - 0.12 11.1 1.2 0.19 10.5 1.2 1.2 1 0 0 1 1 1 0 Type specific antigen Pkinase PF00069.25 EGR27022.1 - 6.1e-10 38.9 1.6 2.3e-09 37.0 0.1 2.6 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27022.1 - 7.9e-07 28.6 0.0 6.3e-06 25.7 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pox_A31 PF05771.11 EGR27022.1 - 9.8e-05 22.3 3.6 0.0043 17.1 0.5 2.9 2 0 0 2 2 2 2 Poxvirus A31 protein LRR_6 PF13516.6 EGR27022.1 - 0.089 12.9 29.0 2.3 8.5 0.1 8.7 9 0 0 9 9 9 0 Leucine Rich repeat Nramp PF01566.18 EGR27023.1 - 1.8e-58 198.3 9.9 2.2e-58 198.0 9.9 1.1 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein RTC PF01137.21 EGR27024.1 - 8.9e-43 146.0 0.0 1.1e-42 145.7 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EGR27024.1 - 2e-26 92.5 0.0 3.5e-26 91.7 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Gcd10p PF04189.13 EGR27024.1 - 0.0015 17.7 1.8 0.0023 17.1 1.8 1.2 1 0 0 1 1 1 1 Gcd10p family Serinc PF03348.15 EGR27024.1 - 0.17 10.8 0.1 0.24 10.3 0.1 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) CobT PF06213.12 EGR27024.1 - 7.3 5.9 9.4 11 5.3 9.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT KASH_CCD PF14662.6 EGR27025.1 - 0.0018 18.2 28.1 0.0062 16.4 28.1 1.8 1 1 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DUF4315 PF14193.6 EGR27025.1 - 0.011 15.8 5.7 0.011 15.8 5.7 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4315) V_ATPase_I PF01496.19 EGR27025.1 - 0.04 11.8 14.7 0.045 11.7 14.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ax_dynein_light PF10211.9 EGR27025.1 - 0.048 13.6 22.4 0.47 10.4 14.1 2.6 1 1 1 2 2 2 0 Axonemal dynein light chain CLZ PF16526.5 EGR27025.1 - 0.063 13.6 18.0 0.14 12.6 6.8 3.3 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels ATG16 PF08614.11 EGR27025.1 - 0.18 12.0 21.3 0.11 12.7 12.7 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Strep_SA_rep PF06696.11 EGR27025.1 - 0.22 11.6 0.2 0.22 11.6 0.2 3.2 3 0 0 3 3 3 0 Streptococcal surface antigen repeat TMCO5 PF14992.6 EGR27025.1 - 0.24 10.9 26.9 0.51 9.9 26.9 1.5 1 1 0 1 1 1 0 TMCO5 family bZIP_1 PF00170.21 EGR27025.1 - 0.46 10.6 24.3 0.78 9.9 6.1 3.7 2 2 2 4 4 4 0 bZIP transcription factor bZIP_2 PF07716.15 EGR27025.1 - 0.79 9.8 26.7 0.086 12.9 2.7 4.5 2 1 3 5 5 5 0 Basic region leucine zipper ALMT PF11744.8 EGR27025.1 - 0.86 8.4 10.7 0.98 8.2 10.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1192 PF06698.11 EGR27025.1 - 0.89 9.7 9.8 4.1 7.5 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) Prefoldin_2 PF01920.20 EGR27025.1 - 0.94 9.5 27.3 0.73 9.8 7.4 3.3 1 1 2 3 3 3 0 Prefoldin subunit Exonuc_VII_L PF02601.15 EGR27025.1 - 0.96 9.0 11.4 1.2 8.7 11.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Plk4_PB2 PF18409.1 EGR27025.1 - 1.5 9.5 9.1 0.67 10.7 3.6 2.1 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 APG6_N PF17675.1 EGR27025.1 - 1.7 9.2 26.9 2 8.9 18.2 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Spc7 PF08317.11 EGR27025.1 - 2 7.2 25.0 4.3 6.1 0.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 EGR27025.1 - 2.2 8.3 30.7 1.1 9.3 2.8 3.7 1 1 3 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 EGR27025.1 - 2.4 8.2 14.3 0.27 11.3 5.8 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 EGR27025.1 - 2.8 7.2 19.4 1.5 8.0 11.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 EGR27025.1 - 3.1 7.0 13.7 1.7 7.8 11.8 1.5 1 1 0 1 1 1 0 TMPIT-like protein Fib_alpha PF08702.10 EGR27025.1 - 3.3 7.9 21.8 12 6.1 14.1 2.5 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Val_tRNA-synt_C PF10458.9 EGR27025.1 - 5.1 7.5 18.2 0.31 11.4 1.5 3.5 3 2 1 4 4 3 0 Valyl tRNA synthetase tRNA binding arm HSP70 PF00012.20 EGR27025.1 - 6.5 4.8 14.4 8.2 4.5 14.4 1.2 1 0 0 1 1 1 0 Hsp70 protein DUF4407 PF14362.6 EGR27025.1 - 7.8 5.8 10.9 9.7 5.4 10.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 EGR27025.1 - 7.8 6.3 20.0 1.3 8.8 9.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF724) PARG_cat PF05028.14 EGR27026.1 - 3e-72 243.7 5.2 3.8e-72 243.4 5.2 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) DUF1160 PF06648.11 EGR27026.1 - 0.02 14.9 0.3 0.02 14.9 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1160) Kelch_3 PF13415.6 EGR27027.1 - 1.9e-23 82.2 0.4 2.3e-06 27.7 0.0 4.8 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EGR27027.1 - 6e-23 80.4 1.1 2e-05 24.4 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 EGR27027.1 - 1.1e-18 67.0 3.2 0.0001 22.2 0.0 4.4 4 0 0 4 4 4 4 Galactose oxidase, central domain Metallophos PF00149.28 EGR27027.1 - 1.8e-15 58.0 0.4 4.8e-15 56.6 0.4 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_6 PF13964.6 EGR27027.1 - 1.6e-11 44.0 1.7 0.019 15.3 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 EGR27027.1 - 3.1e-07 30.1 1.8 1.5 9.0 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 EGR27027.1 - 6.3e-05 22.5 0.6 0.44 10.2 0.0 4.2 4 0 0 4 4 4 1 Kelch motif RAG2 PF03089.14 EGR27027.1 - 0.0002 20.5 0.1 2 7.4 0.0 3.4 2 1 1 3 3 3 3 Recombination activating protein 2 STPPase_N PF16891.5 EGR27027.1 - 0.0028 18.1 0.2 0.006 17.0 0.2 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF647 PF04884.14 EGR27027.1 - 0.052 13.2 0.1 0.089 12.4 0.1 1.3 1 0 0 1 1 1 0 Vitamin B6 photo-protection and homoeostasis Fig1 PF12351.8 EGR27028.1 - 0.21 11.5 0.4 0.32 10.9 0.4 1.3 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 CS PF04969.16 EGR27029.1 - 5.6e-07 30.5 0.0 8.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 CS domain TIP49 PF06068.13 EGR27030.1 - 4.4e-158 526.1 4.3 4.4e-158 526.1 4.3 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 EGR27030.1 - 5e-25 87.4 1.3 1.4e-24 86.0 1.3 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EGR27030.1 - 1.4e-09 38.4 2.5 1.9e-05 25.1 0.4 3.0 1 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGR27030.1 - 3.9e-07 29.9 0.5 0.0015 18.3 0.1 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGR27030.1 - 1.7e-06 28.3 0.3 0.0066 16.7 0.0 2.5 1 1 0 2 2 2 2 AAA domain DnaB_C PF03796.15 EGR27030.1 - 3e-06 26.8 0.4 6.5e-06 25.7 0.4 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 EGR27030.1 - 1.4e-05 25.6 0.1 5.5e-05 23.6 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EGR27030.1 - 1.8e-05 24.8 0.8 0.028 14.4 0.0 3.0 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EGR27030.1 - 0.00033 21.0 4.1 0.02 15.3 4.1 2.7 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGR27030.1 - 0.00068 19.1 1.2 0.084 12.2 0.4 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EGR27030.1 - 0.0013 18.5 0.6 2 8.1 0.0 2.7 3 0 0 3 3 3 2 Sigma-54 interaction domain Zeta_toxin PF06414.12 EGR27030.1 - 0.027 13.8 0.3 0.027 13.8 0.3 2.0 2 0 0 2 2 2 0 Zeta toxin DUF2075 PF09848.9 EGR27030.1 - 0.031 13.5 0.0 0.068 12.4 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.6 EGR27030.1 - 0.035 14.5 4.3 0.076 13.4 0.9 3.0 3 1 0 3 3 3 0 AAA domain AAA_25 PF13481.6 EGR27030.1 - 0.043 13.4 0.1 0.095 12.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain zf-B_box PF00643.24 EGR27031.1 - 1.6e-05 25.0 1.3 1.6e-05 25.0 1.3 2.6 3 0 0 3 3 3 1 B-box zinc finger zf-C4_ClpX PF06689.13 EGR27031.1 - 0.23 11.3 3.5 0.99 9.3 0.2 2.6 2 0 0 2 2 2 0 ClpX C4-type zinc finger Syntaxin-6_N PF09177.11 EGR27031.1 - 2.2 8.9 6.8 1.9 9.1 0.6 3.1 1 1 2 3 3 3 0 Syntaxin 6, N-terminal VSP PF03302.13 EGR27032.1 - 0.0048 15.8 15.8 0.0048 15.8 15.8 5.2 1 1 4 5 5 5 4 Giardia variant-specific surface protein DUF455 PF04305.14 EGR27034.1 - 2.2e-22 79.8 0.0 2.5e-22 79.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF455) UPF0167 PF03691.14 EGR27035.1 - 0.045 13.6 2.4 0.076 12.8 2.4 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0167) ExsD PF16806.5 EGR27035.1 - 0.35 10.7 6.4 0.39 10.6 5.1 1.7 2 0 0 2 2 2 0 Antiactivator protein ExsD CactinC_cactus PF09732.9 EGR27035.1 - 2.2 8.2 9.5 0.39 10.7 3.7 2.5 2 1 0 2 2 2 0 Cactus-binding C-terminus of cactin protein TPR_12 PF13424.6 EGR27036.1 - 5.5e-10 39.4 6.6 9.5e-07 29.0 0.8 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGR27036.1 - 5.2e-09 35.6 10.5 0.016 15.0 0.1 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGR27036.1 - 9.5e-08 31.6 5.6 0.25 11.6 0.2 4.5 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGR27036.1 - 1.2e-07 31.4 1.9 0.033 14.1 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGR27036.1 - 3.4e-06 26.7 4.5 0.094 12.8 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGR27036.1 - 3.7e-05 24.1 5.3 0.03 14.8 2.3 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGR27036.1 - 7e-05 22.7 6.7 0.57 10.5 0.3 4.2 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF3920 PF13058.6 EGR27036.1 - 0.0027 17.9 0.5 0.031 14.5 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3920) DEAD PF00270.29 EGR27037.1 - 2.6e-43 147.8 0.4 3.7e-43 147.3 0.4 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGR27037.1 - 5.3e-06 26.6 0.1 7.3e-06 26.1 0.1 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGR27037.1 - 0.0017 17.7 0.0 0.0033 16.8 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_22 PF13401.6 EGR27037.1 - 0.0034 17.7 0.1 0.01 16.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain Mistic PF11458.8 EGR27037.1 - 0.0078 16.1 0.1 0.02 14.8 0.1 1.7 1 0 0 1 1 1 1 Membrane-integrating protein Mistic Helicase_RecD PF05127.14 EGR27037.1 - 0.013 15.3 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Helicase AAA_30 PF13604.6 EGR27037.1 - 0.015 15.0 0.5 0.052 13.3 0.5 1.8 1 1 0 1 1 1 0 AAA domain HATPase_c PF02518.26 EGR27038.1 - 3.7e-19 69.3 0.8 5.1e-19 68.8 0.8 1.2 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_C2 PF00648.21 EGR27039.1 - 6.8e-53 179.6 0.8 6.8e-53 179.6 0.8 2.0 2 0 0 2 2 2 1 Calpain family cysteine protease AP-5_subunit_s1 PF15001.6 EGR27040.1 - 4 7.4 10.2 0.43 10.6 5.6 1.8 2 0 0 2 2 2 0 AP-5 complex subunit sigma-1 Roughex PF06020.11 EGR27040.1 - 4.9 6.2 8.9 7.1 5.6 8.9 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Ras PF00071.22 EGR27042.1 - 1.6e-10 40.8 0.2 1.6e-10 40.8 0.2 2.8 3 0 0 3 3 3 1 Ras family EF_assoc_2 PF08356.12 EGR27042.1 - 2.1e-10 40.5 1.8 3.6e-10 39.7 0.2 2.3 2 0 0 2 2 2 1 EF hand associated EF_assoc_1 PF08355.12 EGR27042.1 - 0.00072 19.1 0.0 0.0022 17.5 0.0 1.8 1 0 0 1 1 1 1 EF hand associated Roc PF08477.13 EGR27042.1 - 0.0011 19.2 0.4 0.0046 17.2 0.1 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ribosomal_S13 PF00416.22 EGR27042.1 - 0.073 13.5 0.3 0.073 13.5 0.3 2.5 2 0 0 2 2 2 0 Ribosomal protein S13/S18 Claudin_2 PF13903.6 EGR27042.1 - 0.63 9.8 3.5 0.54 10.0 0.1 2.4 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Pyr_redox_2 PF07992.14 EGR27043.1 - 2e-50 171.7 0.1 2.5e-50 171.4 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGR27043.1 - 1.3e-15 57.7 4.7 4.5e-14 52.8 0.1 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGR27043.1 - 1.5e-12 47.4 1.0 1.5e-12 47.4 1.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGR27043.1 - 1.6e-09 38.0 0.0 8.5e-09 35.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain AlaDh_PNT_C PF01262.21 EGR27043.1 - 0.009 15.3 0.0 1.6 8.0 0.0 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 EGR27043.1 - 0.03 14.7 0.5 0.16 12.4 0.0 2.3 2 1 0 2 2 2 0 Putative NAD(P)-binding Ribosomal_S2 PF00318.20 EGR27044.1 - 1.9e-33 115.5 2.0 5.7e-16 58.4 0.6 2.2 1 1 1 2 2 2 2 Ribosomal protein S2 efThoc1 PF11957.8 EGR27045.1 - 7e-47 160.2 15.5 7e-47 160.2 15.5 1.4 2 0 0 2 2 2 1 THO complex subunit 1 transcription elongation factor CNOT11 PF10155.9 EGR27045.1 - 0.063 13.4 2.8 0.075 13.2 1.1 2.0 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 NAP PF00956.18 EGR27046.1 - 4.4e-28 98.2 15.4 1.2e-15 57.4 10.0 3.1 3 0 0 3 3 3 2 Nucleosome assembly protein (NAP) Ras PF00071.22 EGR27048.1 - 4.4e-45 153.2 0.3 5.3e-45 152.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR27048.1 - 2.1e-32 111.9 0.1 3e-32 111.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR27048.1 - 2e-11 43.7 0.1 2.7e-11 43.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGR27048.1 - 6e-08 32.5 0.1 1.2e-06 28.2 0.1 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGR27048.1 - 8.5e-07 28.6 0.1 1.1e-06 28.2 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGR27048.1 - 1.2e-06 28.6 0.0 1.8e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGR27048.1 - 0.0028 17.6 0.0 1.8 8.5 0.0 2.4 1 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EGR27048.1 - 0.012 15.1 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit MMR_HSR1_Xtn PF16897.5 EGR27048.1 - 0.016 15.2 0.2 0.033 14.2 0.2 1.5 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 EGR27048.1 - 0.026 14.9 0.0 0.038 14.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 EGR27048.1 - 0.064 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein UbiA PF01040.18 EGR27049.1 - 6.6e-46 156.7 7.9 7.6e-46 156.4 7.9 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family Tmemb_14 PF03647.13 EGR27049.1 - 0.0021 18.8 3.1 0.0024 18.6 0.6 2.2 2 1 0 2 2 2 1 Transmembrane proteins 14C ATP-synt_C PF00137.21 EGR27050.1 - 4.3e-35 119.8 35.4 3.2e-22 78.6 14.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C GerA PF03323.13 EGR27050.1 - 7.2 4.9 7.9 10 4.4 1.0 2.2 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein Ion_trans PF00520.31 EGR27051.1 - 7.1e-11 41.8 23.9 1.3e-10 41.0 23.9 1.5 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGR27051.1 - 9.7e-10 38.3 5.6 9.7e-10 38.3 5.6 2.2 2 0 0 2 2 2 1 Ion channel TLD PF07534.16 EGR27052.1 - 7.8e-15 55.3 2.4 1.7e-14 54.2 2.4 1.6 1 0 0 1 1 1 1 TLD SNARE PF05739.19 EGR27053.1 - 0.0094 15.9 1.0 0.021 14.8 0.0 2.0 2 0 0 2 2 2 1 SNARE domain Fibin PF15819.5 EGR27053.1 - 0.25 11.1 6.2 0.098 12.4 1.4 2.1 2 0 0 2 2 2 0 Fin bud initiation factor homologue HrpB7 PF09486.10 EGR27053.1 - 0.29 11.5 0.2 0.29 11.5 0.2 2.7 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) Bac_thur_toxin PF01338.18 EGR27053.1 - 0.61 9.5 9.6 0.21 11.0 1.5 2.2 2 0 0 2 2 2 0 Bacillus thuringiensis toxin Med22 PF06179.12 EGR27053.1 - 1 9.6 16.6 0.99 9.6 0.3 3.5 3 1 0 3 3 3 0 Surfeit locus protein 5 subunit 22 of Mediator complex WXG100 PF06013.12 EGR27053.1 - 1.3 9.3 12.9 3.3 8.0 0.7 3.2 2 1 0 3 3 3 0 Proteins of 100 residues with WXG MCPsignal PF00015.21 EGR27053.1 - 2.1 8.1 8.8 0.85 9.4 0.5 2.9 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF948 PF06103.11 EGR27053.1 - 3.4 8.0 11.3 3.2 8.1 0.6 3.8 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) RPW8 PF05659.11 EGR27053.1 - 7.2 6.3 15.2 1.9 8.2 0.5 2.8 2 1 1 3 3 3 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 BLOC1_2 PF10046.9 EGR27053.1 - 8.1 6.8 24.9 0.42 11.0 3.7 3.3 2 1 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Abhydrolase_3 PF07859.13 EGR27054.1 - 1e-49 169.3 0.0 1.4e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGR27054.1 - 7.1e-08 31.7 0.1 9.4e-08 31.3 0.1 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 EGR27054.1 - 7.9e-05 21.7 0.5 0.0012 17.8 0.3 2.2 1 1 0 1 1 1 1 Carboxylesterase family BAAT_C PF08840.11 EGR27054.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal PWWP PF00855.17 EGR27055.1 - 3.5e-11 43.3 0.0 4.1e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 PWWP domain Ribosomal_L27A PF00828.19 EGR27056.1 - 1.4e-23 84.0 0.2 1.9e-23 83.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DNA_mis_repair PF01119.19 EGR27058.1 - 3.3e-17 62.3 1.3 3.3e-17 62.3 1.3 2.2 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EGR27058.1 - 1.2e-13 51.1 1.1 3.1e-13 49.7 1.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGR27058.1 - 2.2e-06 28.2 0.6 2.2e-06 28.2 0.6 2.2 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MSC PF09402.10 EGR27058.1 - 4.5 6.6 17.2 0.96 8.8 13.6 1.7 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain Pkinase PF00069.25 EGR27059.1 - 2.7e-73 246.6 0.5 3.4e-73 246.3 0.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27059.1 - 6.1e-36 124.0 0.0 8.2e-36 123.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27059.1 - 8.2e-09 35.2 0.0 2.1e-08 33.8 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGR27059.1 - 3.8e-07 29.4 0.2 5.7e-07 28.8 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGR27059.1 - 0.019 14.3 0.0 0.029 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Thioredoxin_8 PF13905.6 EGR27060.1 - 8.1e-29 99.8 0.0 1.1e-28 99.3 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 EGR27060.1 - 5.5e-07 29.5 0.3 0.00021 21.2 0.1 2.2 1 1 1 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EGR27060.1 - 0.00061 20.2 0.1 0.0012 19.3 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 EGR27060.1 - 0.0073 16.2 0.0 0.0097 15.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EGR27060.1 - 0.0085 15.9 0.4 0.64 9.8 0.1 2.3 1 1 1 2 2 2 1 Thioredoxin Thioredoxin_7 PF13899.6 EGR27060.1 - 0.17 12.1 0.1 0.51 10.6 0.1 1.9 1 1 0 1 1 1 0 Thioredoxin-like WD40 PF00400.32 EGR27061.1 - 1.7e-18 66.6 7.8 3.8e-05 24.4 0.0 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR27061.1 - 2.2e-15 56.7 5.9 2.2e-07 31.1 0.8 2.9 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGR27061.1 - 1.1e-05 25.4 2.1 0.017 15.0 0.6 2.3 1 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGR27061.1 - 0.001 18.5 0.0 0.067 12.5 0.0 2.2 1 1 1 2 2 2 2 WD40-like domain TTL PF03133.15 EGR27062.1 - 1.6e-59 201.5 9.3 1.6e-59 201.5 9.3 2.0 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family DOR PF14839.6 EGR27062.1 - 1.1 9.1 9.3 2 8.3 9.3 1.3 1 0 0 1 1 1 0 DOR family SNF2_N PF00176.23 EGR27063.1 - 1.2e-65 221.5 4.3 1.2e-65 221.5 4.3 3.2 3 1 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGR27063.1 - 2.5e-20 72.9 0.2 2.5e-20 72.9 0.2 3.3 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DBINO PF13892.6 EGR27063.1 - 1.1e-08 35.5 6.9 1.1e-08 35.5 6.9 6.5 5 2 1 7 7 7 1 DNA-binding domain Cir_N PF10197.9 EGR27064.1 - 2e-12 47.1 9.0 2e-12 47.1 9.0 1.6 2 0 0 2 2 2 1 N-terminal domain of CBF1 interacting co-repressor CIR Fam20C PF06702.12 EGR27064.1 - 0.12 12.2 1.1 0.12 12.2 1.1 1.1 1 0 0 1 1 1 0 Golgi casein kinase, C-terminal, Fam20 MMtag PF10159.9 EGR27065.1 - 9e-18 64.3 4.1 9e-18 64.3 4.1 3.4 2 1 0 2 2 2 1 Multiple myeloma tumor-associated Peptidase_S28 PF05577.12 EGR27066.1 - 5.1e-80 269.4 6.9 5.1e-80 269.4 6.9 7.1 4 2 4 9 9 9 1 Serine carboxypeptidase S28 GBP PF02263.19 EGR27066.1 - 2.5e-67 226.9 0.1 2.5e-67 226.9 0.1 6.5 4 2 1 7 7 7 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 EGR27066.1 - 2.1e-28 99.6 47.3 2.1e-28 99.6 47.3 10.5 2 2 6 9 9 9 1 Guanylate-binding protein, C-terminal domain PSP94 PF05825.11 EGR27066.1 - 0.0074 16.8 1.5 0.11 13.0 0.1 3.4 3 0 0 3 3 3 1 Beta-microseminoprotein (PSP-94) Dynein_light PF01221.18 EGR27067.1 - 5.8e-39 132.3 1.5 6.3e-39 132.2 1.5 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Imm48 PF15574.6 EGR27067.1 - 0.068 12.9 0.2 0.23 11.3 0.1 1.7 1 1 1 2 2 2 0 Immunity protein 48 ABC_membrane PF00664.23 EGR27069.1 - 2.1e-110 368.7 37.1 5.8e-57 193.4 13.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGR27069.1 - 2.8e-73 244.9 12.1 7.8e-39 133.3 0.3 3.6 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EGR27069.1 - 7.8e-16 58.2 20.8 1.6e-06 27.7 0.3 5.0 1 1 2 3 3 3 3 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGR27069.1 - 3.2e-08 33.6 7.3 0.0026 17.7 0.0 3.9 3 2 1 4 4 4 2 RsgA GTPase AAA_16 PF13191.6 EGR27069.1 - 6.5e-08 33.1 1.0 0.0026 18.1 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGR27069.1 - 6.5e-08 32.9 2.7 0.0013 19.0 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGR27069.1 - 8.8e-07 28.6 1.5 0.021 14.5 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EGR27069.1 - 1.2e-06 27.9 0.3 0.055 12.7 0.0 2.8 3 0 0 3 3 2 2 Zeta toxin AAA_7 PF12775.7 EGR27069.1 - 2.9e-06 26.9 0.0 0.095 12.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_15 PF13175.6 EGR27069.1 - 5.2e-06 26.4 20.8 5.2e-06 26.4 20.8 4.4 3 1 1 4 4 4 2 AAA ATPase domain AAA PF00004.29 EGR27069.1 - 6.9e-06 26.5 3.1 0.15 12.5 0.1 4.3 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGR27069.1 - 2.8e-05 24.2 0.1 0.87 9.6 0.0 4.2 4 1 1 5 5 4 2 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 EGR27069.1 - 3.8e-05 23.7 6.9 0.063 13.1 0.0 4.3 3 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 EGR27069.1 - 4.7e-05 23.2 0.2 0.078 12.7 0.0 3.1 2 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EGR27069.1 - 0.00018 21.5 0.2 0.57 10.3 0.6 3.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 EGR27069.1 - 0.00034 20.3 0.0 0.34 10.5 0.0 2.5 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain SbcCD_C PF13558.6 EGR27069.1 - 0.0044 17.2 1.1 6 7.2 0.1 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 EGR27069.1 - 0.0065 16.8 0.6 3.3 8.1 0.0 3.9 3 1 1 4 4 3 1 RNA helicase Sigma54_activat PF00158.26 EGR27069.1 - 0.01 15.5 0.0 0.88 9.2 0.0 3.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 EGR27069.1 - 0.013 15.2 0.7 1.1 8.9 0.1 2.8 2 1 0 2 2 2 0 AAA domain PRK PF00485.18 EGR27069.1 - 0.014 15.2 0.4 5.3 6.7 0.0 3.3 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family IstB_IS21 PF01695.17 EGR27069.1 - 0.026 14.3 4.7 6.4 6.5 0.0 4.3 5 0 0 5 5 5 0 IstB-like ATP binding protein ECH_2 PF16113.5 EGR27069.1 - 0.028 13.9 2.8 1.2 8.6 0.1 3.3 3 0 0 3 3 3 0 Enoyl-CoA hydratase/isomerase APS_kinase PF01583.20 EGR27069.1 - 0.058 13.3 0.0 4.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_33 PF13671.6 EGR27069.1 - 0.071 13.3 0.0 4.6 7.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain Oxidored_q2 PF00420.24 EGR27069.1 - 0.082 12.5 1.5 0.14 11.8 0.0 2.2 2 0 0 2 2 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L NACHT PF05729.12 EGR27069.1 - 0.097 12.6 0.2 14 5.6 0.0 3.3 3 0 0 3 3 3 0 NACHT domain Roc PF08477.13 EGR27069.1 - 0.17 12.1 6.0 6.3 7.0 0.0 3.6 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase YokU PF14122.6 EGR27069.1 - 0.27 11.2 3.3 0.52 10.3 0.1 3.0 3 0 0 3 3 3 0 YokU-like protein, putative antitoxin AAA_18 PF13238.6 EGR27069.1 - 0.28 11.7 5.8 15 6.1 0.0 4.0 4 0 0 4 4 3 0 AAA domain ABC_ATPase PF09818.9 EGR27069.1 - 0.53 9.0 9.0 0.49 9.1 0.1 3.1 4 0 0 4 4 3 0 Predicted ATPase of the ABC class FtsK_SpoIIIE PF01580.18 EGR27069.1 - 1.1 8.6 3.2 6 6.2 0.0 3.0 3 0 0 3 3 3 0 FtsK/SpoIIIE family NUDIX PF00293.28 EGR27070.1 - 3.2e-11 43.4 0.0 3.8e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain Fer4 PF00037.27 EGR27071.1 - 3.9e-14 51.8 15.4 3.8e-08 32.8 4.5 2.5 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EGR27071.1 - 6.1e-12 45.9 11.8 7.1e-12 45.7 10.4 1.9 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGR27071.1 - 4.8e-08 33.0 9.6 9.9e-08 32.0 9.6 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EGR27071.1 - 6.6e-08 32.2 12.5 0.00037 20.4 3.2 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 EGR27071.1 - 4e-07 30.0 23.3 5.1e-06 26.5 13.0 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_16 PF13484.6 EGR27071.1 - 6.6e-07 30.2 11.8 0.00096 20.0 12.7 2.7 1 1 1 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EGR27071.1 - 1e-06 28.8 21.5 3e-05 24.0 12.1 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGR27071.1 - 1.1e-05 25.8 11.2 0.0005 20.5 13.4 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EGR27071.1 - 5.5e-05 23.1 16.9 0.032 14.3 4.5 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EGR27071.1 - 0.0003 21.1 12.0 0.0066 16.9 2.2 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EGR27071.1 - 0.0044 17.5 13.4 0.1 13.2 13.6 2.6 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_13 PF13370.6 EGR27071.1 - 0.019 15.5 14.3 0.68 10.5 4.0 2.8 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_3 PF12798.7 EGR27071.1 - 0.39 11.7 16.9 0.73 10.9 4.1 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_18 PF13746.6 EGR27071.1 - 1.1 9.5 9.3 2.3e+02 2.0 8.7 2.5 1 1 0 1 1 1 0 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 EGR27071.1 - 5 7.4 7.6 7.3 6.9 0.5 2.8 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_22 PF17179.4 EGR27071.1 - 5 8.0 12.2 4.6 8.2 1.6 2.7 1 1 2 3 3 2 0 4Fe-4S dicluster domain Pkinase PF00069.25 EGR27072.1 - 2.1e-58 197.8 0.0 2.5e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27072.1 - 1.6e-40 139.0 0.0 2e-40 138.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR27072.1 - 3.2e-07 29.5 0.0 5.5e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase SPO22 PF08631.10 EGR27073.1 - 0.06 12.8 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like Pkinase PF00069.25 EGR27075.1 - 3.3e-33 115.2 0.7 8.2e-18 64.7 0.1 4.2 3 2 1 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27075.1 - 5.2e-10 39.0 17.1 6.4e-06 25.6 0.0 4.4 3 2 1 4 4 4 2 Protein tyrosine kinase Suf PF05843.14 EGR27075.1 - 0.18 11.8 29.6 0.5 10.3 29.6 1.8 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pribosyltran_N PF13793.6 EGR27076.1 - 2e-47 159.9 0.1 1.9e-46 156.7 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EGR27076.1 - 1.6e-28 100.0 0.2 3.6e-28 98.8 0.2 1.6 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EGR27076.1 - 2.2e-16 59.8 0.1 5.7e-16 58.4 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGR27076.1 - 0.0011 18.5 0.1 0.0019 17.7 0.1 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase SurA_N_2 PF13623.6 EGR27077.1 - 0.0039 17.1 1.9 0.18 11.7 1.0 2.8 2 0 0 2 2 2 2 SurA N-terminal domain Dpy-30 PF05186.13 EGR27078.1 - 6.8e-14 51.3 0.2 1.4e-13 50.3 0.2 1.5 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 EGR27078.1 - 2.5e-08 34.2 4.8 0.003 17.7 0.2 3.7 2 1 0 3 3 3 2 Adenylate kinase AAA_17 PF13207.6 EGR27078.1 - 0.00022 21.6 0.2 0.00022 21.6 0.2 3.9 2 1 1 3 3 3 1 AAA domain Hydin_ADK PF17213.3 EGR27078.1 - 0.0006 20.2 0.0 0.0006 20.2 0.0 3.7 4 1 1 5 5 5 1 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 EGR27078.1 - 0.0015 19.1 0.0 0.0015 19.1 0.0 5.1 3 2 0 4 4 4 1 AAA domain AAA_33 PF13671.6 EGR27078.1 - 0.0035 17.5 0.0 0.018 15.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EGR27078.1 - 0.086 13.1 1.1 0.94 9.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EGR27078.1 - 0.1 11.9 0.0 0.1 11.9 0.0 2.2 2 1 1 3 3 3 0 KaiC FtsK_SpoIIIE PF01580.18 EGR27078.1 - 0.16 11.3 0.1 8 5.7 0.0 2.4 1 1 1 2 2 2 0 FtsK/SpoIIIE family Exonuc_VII_L PF02601.15 EGR27078.1 - 1.2 8.6 12.4 4.1 6.9 0.4 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit Kinesin PF00225.23 EGR27079.1 - 1e-104 350.1 8.7 1.2e-104 349.9 8.7 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR27079.1 - 1.9e-24 86.3 8.5 8e-24 84.3 8.5 2.1 1 1 0 1 1 1 1 Microtubule binding MG4 PF17789.1 EGR27080.1 - 0.021 15.0 0.2 7 6.9 0.0 3.6 3 0 0 3 3 3 0 Macroglobulin domain MG4 ArfGap PF01412.18 EGR27081.1 - 1.2e-28 99.6 0.0 1.2e-28 99.6 0.0 3.2 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf zf-UBP PF02148.19 EGR27081.1 - 0.038 14.3 0.0 0.071 13.5 0.0 1.5 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein Histidinol_dh PF00815.20 EGR27081.1 - 2.5 7.0 6.9 3.6 6.5 6.9 1.2 1 0 0 1 1 1 0 Histidinol dehydrogenase JAB PF01398.21 EGR27082.1 - 9.6e-29 99.8 0.1 1.6e-28 99.0 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 EGR27082.1 - 8e-05 23.5 2.8 0.001 19.9 0.8 2.8 2 1 0 2 2 2 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 EGR27082.1 - 0.00065 19.5 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 EGR27082.1 - 0.044 13.8 0.0 0.065 13.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) HD PF01966.22 EGR27083.1 - 2e-10 41.0 0.1 1.3e-09 38.3 0.0 2.3 2 0 0 2 2 2 1 HD domain Peptidase_M1 PF01433.20 EGR27083.1 - 0.034 13.7 0.4 0.077 12.5 0.4 1.5 1 0 0 1 1 1 0 Peptidase family M1 domain DUF4507 PF14964.6 EGR27083.1 - 0.047 12.6 1.5 0.077 11.9 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4507) Pyr_redox_2 PF07992.14 EGR27084.1 - 9.2e-10 38.2 0.0 8.8e-09 35.0 0.0 2.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGR27084.1 - 0.0018 18.3 0.0 0.0076 16.2 0.0 2.1 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EGR27084.1 - 0.0095 15.2 1.2 4 6.6 0.0 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EGR27084.1 - 0.014 15.8 0.0 0.54 10.7 0.0 2.6 2 0 0 2 2 2 0 Putative NAD(P)-binding Fibrinogen_BP PF08017.11 EGR27084.1 - 0.072 11.5 1.6 0.12 10.8 0.5 1.7 2 0 0 2 2 2 0 Fibrinogen binding protein NAD_binding_8 PF13450.6 EGR27084.1 - 0.073 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGR27084.1 - 0.081 12.1 0.0 0.89 8.8 0.0 2.4 3 0 0 3 3 3 0 Thi4 family HI0933_like PF03486.14 EGR27084.1 - 0.1 11.3 0.2 0.27 9.9 0.0 1.8 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox PF00070.27 EGR27084.1 - 0.18 12.4 1.7 17 6.0 0.0 3.7 4 0 0 4 4 4 0 Pyridine nucleotide-disulphide oxidoreductase DUF5424 PF17462.2 EGR27084.1 - 2.4 8.1 9.4 0.67 9.9 3.3 2.3 1 1 0 2 2 2 0 Family of unknown function (DUF5424) zf-HC5HC2H PF13771.6 EGR27086.1 - 2.9e-06 27.4 6.0 2.9e-06 27.4 6.0 1.4 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EGR27086.1 - 0.00011 22.3 4.8 0.00019 21.6 4.8 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-LITAF-like PF10601.9 EGR27088.1 - 2e-20 72.8 17.6 3e-20 72.2 17.6 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain PAT1 PF09770.9 EGR27088.1 - 4 5.6 15.3 4.5 5.4 15.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Ribosomal_L32p PF01783.23 EGR27088.1 - 7.6 6.9 7.7 16 5.8 0.4 3.3 3 1 0 3 3 3 0 Ribosomal L32p protein family Rop-like PF05082.13 EGR27090.1 - 0.02 14.7 0.2 0.31 10.9 0.1 2.8 2 0 0 2 2 2 0 Rop-like UPF0149 PF03695.13 EGR27090.1 - 0.032 14.5 0.0 0.055 13.8 0.0 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0149) 5_nucleotid PF05761.14 EGR27091.1 - 2.7e-55 188.1 14.1 3.6e-55 187.7 14.1 1.1 1 0 0 1 1 1 1 5' nucleotidase family Peptidase_S66C PF17676.1 EGR27091.1 - 0.0031 18.0 0.2 1.2 9.7 0.0 2.5 2 0 0 2 2 2 2 LD-carboxypeptidase C-terminal domain SurA_N_2 PF13623.6 EGR27092.1 - 0.00017 21.5 6.4 0.00026 20.9 6.4 1.4 1 0 0 1 1 1 1 SurA N-terminal domain MobA_MobL PF03389.15 EGR27092.1 - 0.0019 18.0 0.7 0.0022 17.8 0.7 1.1 1 0 0 1 1 1 1 MobA/MobL family FapA PF03961.13 EGR27092.1 - 0.018 13.6 6.8 0.019 13.6 6.8 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Peptidase_S49_N PF08496.10 EGR27092.1 - 0.038 14.1 5.5 0.052 13.6 5.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Spt20 PF12090.8 EGR27092.1 - 0.047 13.3 15.5 0.055 13.1 15.5 1.2 1 0 0 1 1 1 0 Spt20 family MMR1 PF08505.10 EGR27092.1 - 0.16 12.2 10.9 0.19 12.0 10.9 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DUF3367 PF11847.8 EGR27092.1 - 0.18 9.7 0.3 0.2 9.5 0.3 1.1 1 0 0 1 1 1 0 Alpha-(1->3)-arabinofuranosyltransferase Connexin PF00029.19 EGR27092.1 - 0.25 11.1 2.2 0.3 10.8 2.2 1.2 1 0 0 1 1 1 0 Connexin O-antigen_lig PF13425.6 EGR27092.1 - 1.9 7.2 3.9 2 7.1 3.9 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DivIC PF04977.15 EGR27092.1 - 2.2 8.1 12.9 3.7 7.4 12.9 1.4 1 0 0 1 1 1 0 Septum formation initiator Presenilin PF01080.17 EGR27092.1 - 3.8 6.2 7.0 3.8 6.2 7.0 1.1 1 0 0 1 1 1 0 Presenilin ZYG-11_interact PF05884.12 EGR27092.1 - 5.5 6.3 5.7 6.4 6.1 5.7 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 GpcrRhopsn4 PF10192.9 EGR27093.1 - 9e-19 67.9 7.5 1e-18 67.7 7.5 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 EGR27093.1 - 0.0011 18.3 1.9 0.0013 18.1 1.9 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF905 PF06006.12 EGR27094.1 - 0.13 12.2 0.1 0.3 11.1 0.0 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF905) zf-CCCH PF00642.24 EGR27096.1 - 1.7e-21 75.6 19.4 1.2e-08 34.6 1.9 3.2 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGR27096.1 - 1.1e-16 60.2 28.0 9.2e-08 31.9 4.6 3.4 3 0 0 3 3 3 3 Zinc finger domain zf-CCCH_4 PF18044.1 EGR27096.1 - 3.3e-09 36.3 20.4 0.00022 20.9 2.1 3.3 3 0 0 3 3 3 3 CCCH-type zinc finger Torus PF16131.5 EGR27096.1 - 2.2e-08 34.7 24.8 0.00026 21.6 2.9 3.8 1 1 3 4 4 4 3 Torus domain zf-CCCH_3 PF15663.5 EGR27096.1 - 7e-06 26.2 11.5 0.0003 21.0 3.0 2.5 1 1 0 2 2 2 2 Zinc-finger containing family zf-CCCH_2 PF14608.6 EGR27096.1 - 3.5e-05 24.1 22.8 0.00029 21.2 3.2 3.6 3 0 0 3 3 3 2 RNA-binding, Nab2-type zinc finger UPF0016 PF01169.19 EGR27097.1 - 1.9e-34 117.8 11.8 3.5e-23 81.7 2.3 2.1 2 0 0 2 2 2 2 Uncharacterized protein family UPF0016 Mntp PF02659.15 EGR27097.1 - 8.3e-05 22.4 2.8 0.13 12.1 1.0 2.3 2 0 0 2 2 2 2 Putative manganese efflux pump TauE PF01925.19 EGR27097.1 - 0.00044 20.0 0.6 0.84 9.2 0.0 2.1 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE Mt_ATP-synt_B PF05405.14 EGR27097.1 - 0.0021 17.7 1.7 0.0034 17.0 1.7 1.3 1 0 0 1 1 1 1 Mitochondrial ATP synthase B chain precursor (ATP-synt_B) AvrM-A PF18241.1 EGR27097.1 - 0.0046 17.4 1.0 0.0065 16.9 1.0 1.1 1 0 0 1 1 1 1 Flax-rust effector AvrM-A DUF3829 PF12889.7 EGR27097.1 - 0.008 15.7 1.0 0.01 15.3 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) TMPIT PF07851.13 EGR27097.1 - 0.016 14.5 1.1 0.031 13.5 1.1 1.4 1 0 0 1 1 1 0 TMPIT-like protein OPA3 PF07047.12 EGR27097.1 - 0.04 13.7 0.2 0.075 12.8 0.2 1.4 1 0 0 1 1 1 0 Optic atrophy 3 protein (OPA3) AAA_17 PF13207.6 EGR27097.1 - 0.063 13.7 0.3 0.087 13.2 0.3 1.1 1 0 0 1 1 1 0 AAA domain DHHA1 PF02272.19 EGR27097.1 - 0.07 13.5 0.5 0.11 12.9 0.5 1.3 1 0 0 1 1 1 0 DHHA1 domain SlyX PF04102.12 EGR27097.1 - 0.079 13.6 1.3 0.13 12.9 1.3 1.3 1 0 0 1 1 1 0 SlyX DivIC PF04977.15 EGR27097.1 - 0.27 11.1 6.4 2.8 7.8 0.8 2.6 1 1 1 2 2 2 0 Septum formation initiator DUF2205 PF10224.9 EGR27097.1 - 0.86 9.6 6.7 1.9 8.6 6.7 1.6 1 1 0 1 1 1 0 Short coiled-coil protein LysE PF01810.18 EGR27097.1 - 4.6 6.7 10.7 93 2.4 10.7 2.3 1 1 0 1 1 1 0 LysE type translocator FAM221 PF14753.6 EGR27098.1 - 0.023 14.2 0.1 0.041 13.4 0.1 1.4 1 0 0 1 1 1 0 Protein FAM221A/B DUF2816 PF10992.8 EGR27099.1 - 1.3e-26 92.2 22.6 4.4e-26 90.5 14.5 3.5 2 1 1 3 3 3 2 Protein of unknown function (DUF2816) Pkinase PF00069.25 EGR27100.1 - 1.2e-57 195.3 0.4 1.4e-57 195.1 0.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27100.1 - 1.3e-26 93.4 0.1 3.4e-26 92.1 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27100.1 - 7.8e-05 22.1 0.1 0.00017 21.0 0.1 1.5 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EGR27100.1 - 0.0042 16.7 0.2 0.0071 16.0 0.2 1.4 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EGR27100.1 - 0.011 15.4 0.4 0.019 14.6 0.4 1.4 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 EGR27100.1 - 0.014 14.8 0.6 0.023 14.1 0.6 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR27100.1 - 0.052 12.3 0.1 0.24 10.1 0.1 1.8 1 1 1 2 2 2 0 Fungal protein kinase KTSC PF13619.6 EGR27100.1 - 0.071 12.9 0.5 4.1 7.3 0.2 2.7 2 0 0 2 2 2 0 KTSC domain Pkinase PF00069.25 EGR27101.1 - 1e-53 182.4 0.2 2.5e-53 181.1 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27101.1 - 6.3e-29 101.0 0.0 1.3e-28 100.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27101.1 - 5.4e-07 29.2 0.1 0.00025 20.4 0.0 2.9 2 1 0 2 2 2 2 Kinase-like Kdo PF06293.14 EGR27101.1 - 0.0018 17.7 1.5 0.0025 17.2 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1959 PF09218.10 EGR27101.1 - 0.002 18.3 1.0 0.0051 16.9 1.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1959) APH PF01636.23 EGR27101.1 - 0.0027 17.7 0.0 0.22 11.4 0.1 2.2 1 1 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGR27101.1 - 0.016 14.8 6.1 0.23 11.0 0.1 2.9 3 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGR27101.1 - 0.029 13.1 0.0 0.029 13.1 0.0 2.1 3 0 0 3 3 3 0 Fungal protein kinase PG_binding_1 PF01471.18 EGR27101.1 - 0.12 12.6 0.3 0.75 10.0 0.1 2.4 3 0 0 3 3 3 0 Putative peptidoglycan binding domain RIO1 PF01163.22 EGR27101.1 - 0.16 11.6 0.1 0.16 11.6 0.1 3.1 3 1 0 3 3 3 0 RIO1 family Pkinase PF00069.25 EGR27102.1 - 2.8e-55 187.5 1.7 2.8e-55 187.5 1.7 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27102.1 - 3.4e-28 98.6 1.8 9.4e-27 93.9 1.8 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR27102.1 - 0.07 13.0 0.0 0.2 11.5 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 EGR27103.1 - 6.5e-57 192.9 0.9 1e-56 192.2 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.29 EGR27103.1 - 2.9e-38 129.8 0.2 1.6e-16 60.1 0.0 3.6 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 EGR27103.1 - 6.7e-28 97.7 0.2 6.9e-27 94.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR27103.1 - 0.00011 21.2 0.0 0.0002 20.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase tRNA-synt_His PF13393.6 EGR27104.1 - 1.7e-21 76.8 0.2 3.2e-21 75.9 0.1 1.2 1 1 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 EGR27104.1 - 1.2e-11 45.0 1.8 1.7e-11 44.4 1.8 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Shugoshin_N PF07558.11 EGR27105.1 - 0.00089 19.1 0.2 0.0057 16.5 0.2 2.6 1 0 0 1 1 1 1 Shugoshin N-terminal coiled-coil region NYD-SP28_assoc PF14775.6 EGR27105.1 - 0.016 15.3 2.8 0.016 15.3 2.8 3.6 5 0 0 5 5 5 0 Sperm tail C-terminal domain CHASE6_C PF17150.4 EGR27105.1 - 0.3 11.8 5.4 0.24 12.1 1.6 2.9 2 1 1 3 3 3 0 C-terminal domain of two-partite extracellular sensor domain ETRAMP PF09716.10 EGR27105.1 - 9.2 6.4 11.3 0.47 10.5 4.1 2.8 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) SpoIIE PF07228.12 EGR27106.1 - 0.0032 17.4 0.0 0.0089 16.0 0.0 1.6 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EGR27106.1 - 0.081 12.5 0.1 0.098 12.3 0.1 1.1 1 0 0 1 1 1 0 Protein phosphatase 2C Phage_GP20 PF06810.11 EGR27107.1 - 0.0015 18.3 0.8 0.0018 18.1 0.8 1.0 1 0 0 1 1 1 1 Phage minor structural protein GP20 SNARE PF05739.19 EGR27107.1 - 0.0059 16.6 0.2 0.0076 16.2 0.2 1.3 1 0 0 1 1 1 1 SNARE domain XhlA PF10779.9 EGR27107.1 - 0.014 15.6 1.9 0.028 14.6 1.9 1.5 1 1 0 1 1 1 0 Haemolysin XhlA Prefoldin_2 PF01920.20 EGR27107.1 - 0.015 15.2 0.5 0.017 15.0 0.5 1.0 1 0 0 1 1 1 0 Prefoldin subunit BLOC1_2 PF10046.9 EGR27107.1 - 0.027 14.8 0.7 0.032 14.5 0.7 1.1 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 EGR27107.1 - 0.044 14.3 0.6 0.049 14.1 0.6 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 EGR27107.1 - 0.049 13.9 1.0 0.056 13.7 1.0 1.1 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Fusion_gly PF00523.18 EGR27107.1 - 0.057 11.7 0.7 0.067 11.4 0.7 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0 Bacteriocin_IIc PF10439.9 EGR27107.1 - 0.066 13.3 5.4 0.1 12.7 5.4 1.2 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Oleosin PF01277.17 EGR27107.1 - 0.088 12.6 0.1 0.16 11.8 0.1 1.4 1 0 0 1 1 1 0 Oleosin HSP90 PF00183.18 EGR27108.1 - 7.7e-188 625.6 64.3 8.3e-187 622.2 64.3 2.6 1 1 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 EGR27108.1 - 1.8e-12 47.2 2.4 6.8e-12 45.4 1.1 2.4 1 1 1 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGR27108.1 - 1.2e-10 41.9 0.5 2.3e-10 41.0 0.5 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CobT PF06213.12 EGR27108.1 - 7.9e-05 22.2 8.6 7.9e-05 22.2 8.6 3.2 3 0 0 3 3 3 3 Cobalamin biosynthesis protein CobT CDC45 PF02724.14 EGR27108.1 - 1.7 6.8 48.8 0.024 13.0 12.1 3.1 3 0 0 3 3 3 0 CDC45-like protein Sigma70_ner PF04546.13 EGR27108.1 - 7.3 6.4 42.2 0.24 11.3 8.0 4.1 4 0 0 4 4 4 0 Sigma-70, non-essential region BET PF17035.5 EGR27109.1 - 8.1e-12 45.1 1.3 9.3e-12 44.9 1.3 1.1 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation TPR_1 PF00515.28 EGR27110.1 - 3.5e-05 23.4 0.0 0.0013 18.4 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGR27110.1 - 4e-05 23.4 0.0 0.00042 20.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGR27110.1 - 0.00013 21.6 0.7 0.0008 19.0 0.0 2.4 1 1 1 2 2 2 2 TPR repeat TPR_12 PF13424.6 EGR27110.1 - 0.065 13.5 0.0 0.21 11.9 0.0 1.8 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF4047 PF13256.6 EGR27110.1 - 0.11 12.7 2.8 0.15 12.3 2.8 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4047) TPR_2 PF07719.17 EGR27111.1 - 2.8e-14 52.0 2.6 0.064 13.4 0.0 5.4 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGR27111.1 - 2.9e-13 49.0 13.1 0.0088 15.8 0.2 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGR27111.1 - 3.9e-07 29.8 9.6 0.25 11.6 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGR27111.1 - 8.1e-07 29.2 0.1 1.4 9.3 0.0 4.0 1 1 2 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGR27111.1 - 0.00017 21.2 3.8 0.34 10.6 0.3 4.3 4 1 0 4 4 4 2 TPR repeat TPR_19 PF14559.6 EGR27111.1 - 0.0046 17.4 0.1 0.044 14.3 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 EGR27111.1 - 0.006 16.6 6.3 1.7 8.8 0.2 4.1 3 1 1 4 4 4 2 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 EGR27111.1 - 0.0061 16.8 6.5 0.012 15.8 0.8 2.7 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGR27111.1 - 0.0066 17.0 0.9 1.5 9.6 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGR27111.1 - 0.0074 16.2 0.0 8.1 6.7 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 EGR27111.1 - 0.0079 16.5 0.1 0.026 14.9 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGR27111.1 - 0.058 14.2 0.0 16 6.6 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGR27111.1 - 0.1 12.5 0.1 2.9 7.9 0.0 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGR27111.1 - 4.3 7.9 8.2 26 5.5 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat CarboxypepD_reg PF13620.6 EGR27112.1 - 1.4e-40 137.5 0.0 3.5e-06 27.2 0.0 11.1 11 0 0 11 11 11 7 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 EGR27112.1 - 1.4e-12 47.5 41.1 0.0037 17.2 0.6 11.5 11 0 0 11 11 11 5 CarboxypepD_reg-like domain Big_1 PF02369.16 EGR27112.1 - 4.7e-11 42.5 10.3 0.025 14.6 0.2 8.8 10 0 0 10 10 10 2 Bacterial Ig-like domain (group 1) TTR-52 PF01060.23 EGR27112.1 - 2.6e-09 37.7 21.5 0.36 11.6 0.1 9.4 10 0 0 10 10 10 4 Transthyretin-like family YtkA PF13115.6 EGR27112.1 - 1.5e-06 28.7 6.4 1.4 9.5 0.1 7.8 8 0 0 8 8 8 2 YtkA-like SdrD_B PF17210.3 EGR27112.1 - 2.9 8.2 11.3 10 6.4 0.1 5.8 6 0 0 6 6 6 0 SdrD B-like domain ASH PF15780.5 EGR27115.1 - 2.7e-24 85.2 19.7 0.0043 17.2 0.0 14.4 14 0 0 14 14 14 7 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 EGR27115.1 - 6.6e-10 38.8 53.7 0.0067 16.3 1.1 12.5 13 0 0 13 13 13 7 MSP (Major sperm protein) domain CH PF00307.31 EGR27115.1 - 3e-07 30.6 0.1 1.9e-06 28.0 0.2 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain PapD-like PF14874.6 EGR27115.1 - 3.5e-05 23.9 0.1 0.0022 18.1 0.0 3.4 2 0 0 2 2 2 1 Flagellar-associated PapD-like CAMSAP_CH PF11971.8 EGR27115.1 - 0.025 14.4 1.5 0.2 11.5 0.3 2.8 2 0 0 2 2 2 0 CAMSAP CH domain DUF2513 PF10711.9 EGR27116.1 - 0.0056 16.9 0.5 0.04 14.2 0.5 2.0 1 1 0 1 1 1 1 Hypothetical protein (DUF2513) DUF3958 PF13125.6 EGR27116.1 - 0.03 14.5 2.3 0.031 14.5 1.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3958) Prok-E2_E PF14462.6 EGR27116.1 - 0.27 11.1 3.6 0.35 10.7 0.8 2.0 1 1 1 2 2 2 0 Prokaryotic E2 family E Pkinase PF00069.25 EGR27117.1 - 6.1e-47 160.2 6.7 8e-47 159.8 6.7 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27117.1 - 7.7e-30 104.0 1.5 1e-29 103.7 1.5 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27117.1 - 1.1e-06 28.2 0.0 1.1e-05 24.9 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EGR27117.1 - 1.7e-05 24.3 0.2 2.7e-05 23.6 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGR27117.1 - 0.00011 21.3 4.1 0.00011 21.3 4.1 1.4 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGR27117.1 - 0.025 13.3 0.8 0.041 12.6 0.2 1.6 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 EGR27117.1 - 0.12 12.2 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ham1p_like PF01725.16 EGR27118.1 - 1.5e-51 175.0 0.0 3.6e-51 173.8 0.0 1.7 2 0 0 2 2 2 1 Ham1 family Ras PF00071.22 EGR27119.1 - 8.8e-46 155.5 2.5 2.2e-42 144.4 2.5 2.2 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGR27119.1 - 1.6e-30 105.8 1.5 6.4e-29 100.6 1.5 2.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR27119.1 - 6.9e-08 32.1 0.7 1.1e-06 28.2 0.7 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR27119.1 - 0.00058 19.9 0.0 0.0011 19.1 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGR27119.1 - 0.0011 18.4 0.3 0.0015 17.9 0.3 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.6 EGR27119.1 - 0.011 15.5 0.2 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EGR27119.1 - 0.049 13.0 0.0 0.086 12.2 0.0 1.5 1 1 0 1 1 1 0 Bacterial TniB protein GTP_EFTU PF00009.27 EGR27119.1 - 0.072 12.6 0.0 0.17 11.4 0.0 1.5 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EGR27119.1 - 0.079 12.7 2.6 5.6 6.7 0.2 2.5 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation CBFB_NFYA PF02045.15 EGR27119.1 - 0.17 12.5 5.3 0.32 11.7 5.3 1.4 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B PALP PF00291.25 EGR27120.1 - 1.3e-57 195.5 0.0 1.5e-57 195.3 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Ion_trans PF00520.31 EGR27121.1 - 1.2e-106 355.4 132.2 6.8e-35 120.5 22.6 4.4 4 0 0 4 4 4 4 Ion transport protein EF-hand_1 PF00036.32 EGR27121.1 - 0.019 14.5 0.0 0.11 12.1 0.0 2.4 1 0 0 1 1 1 0 EF hand GPHH PF16905.5 EGR27121.1 - 0.045 13.5 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 Voltage-dependent L-type calcium channel, IQ-associated CRAL_TRIO PF00650.20 EGR27122.1 - 2.6e-19 69.5 0.3 6.2e-16 58.5 0.3 2.4 1 1 1 2 2 2 2 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EGR27122.1 - 0.00054 20.1 0.1 0.0012 19.0 0.1 1.5 1 1 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGR27122.1 - 0.077 13.2 0.1 0.22 11.7 0.1 1.8 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain TPR_12 PF13424.6 EGR27123.1 - 0.0054 17.0 0.6 0.49 10.7 0.1 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat Suf PF05843.14 EGR27125.1 - 0.064 13.2 11.0 1.2 9.0 0.1 3.9 2 2 1 3 3 3 0 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EGR27125.1 - 0.16 12.8 0.4 18 6.5 0.1 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EGR27125.1 - 0.76 9.8 7.3 4 7.4 0.2 3.9 3 2 1 5 5 5 0 Mad3/BUB1 homology region 1 Ion_trans PF00520.31 EGR27126.1 - 4.8e-05 22.7 4.8 4.9e-05 22.7 4.8 1.1 1 0 0 1 1 1 1 Ion transport protein TMEM220 PF15071.6 EGR27126.1 - 0.00082 20.1 0.1 0.0095 16.7 0.0 2.3 2 1 0 2 2 2 1 Transmembrane family 220, helix T2SS_PulS_OutS PF09691.10 EGR27127.1 - 0.0061 16.7 2.7 0.01 16.0 2.7 1.3 1 0 0 1 1 1 1 Type II secretion system pilotin lipoprotein (PulS_OutS) Cgr1 PF03879.14 EGR27127.1 - 0.0081 16.5 16.2 0.011 16.1 16.2 1.2 1 0 0 1 1 1 1 Cgr1 family DUF1640 PF07798.11 EGR27127.1 - 0.013 15.5 9.2 0.013 15.5 9.2 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1640) TMEM51 PF15345.6 EGR27127.1 - 0.023 14.5 2.7 0.031 14.1 2.7 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DUF2258 PF10015.9 EGR27127.1 - 0.03 14.5 4.8 0.49 10.6 0.1 2.3 1 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) DIT1_PvcA PF05141.12 EGR27127.1 - 0.13 11.7 11.1 0.14 11.6 11.1 1.0 1 0 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein DUF573 PF04504.14 EGR27127.1 - 0.87 10.3 14.9 0.33 11.6 11.4 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF573 DUF4407 PF14362.6 EGR27127.1 - 1.4 8.2 9.3 1.6 8.0 9.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 EGR27127.1 - 1.7 9.3 16.5 2 9.1 15.4 1.7 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Exonuc_VII_L PF02601.15 EGR27127.1 - 6.7 6.2 11.5 7.1 6.1 11.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit M16C_assoc PF08367.11 EGR27127.1 - 9.3 5.3 16.5 12 4.9 12.0 2.1 1 1 1 2 2 2 0 Peptidase M16C associated Acetyltransf_11 PF13720.6 EGR27129.1 - 0.38 11.2 3.1 6.4 7.3 0.1 2.7 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 TTL PF03133.15 EGR27130.1 - 3.1e-55 187.4 14.5 4.5e-55 186.9 14.5 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR27130.1 - 1.3e-10 40.9 0.6 7.8e-05 22.0 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR27130.1 - 0.0019 17.5 0.0 0.038 13.2 0.0 2.3 2 1 0 2 2 2 1 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 EGR27130.1 - 0.023 14.3 0.0 0.99 8.9 0.0 2.5 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus PAS_6 PF08348.11 EGR27130.1 - 0.043 13.7 2.3 0.046 13.6 0.3 2.0 2 0 0 2 2 2 0 YheO-like PAS domain CdiI PF07262.11 EGR27130.1 - 0.073 12.8 5.3 0.17 11.6 5.3 1.7 1 0 0 1 1 1 0 CDI immunity protein DUF2833 PF11090.8 EGR27130.1 - 0.11 12.8 2.5 1.3 9.4 0.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2833) Pkinase PF00069.25 EGR27131.1 - 9.5e-09 35.0 1.1 1.6e-08 34.3 1.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27131.1 - 0.0041 16.4 0.1 0.0053 16.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR27131.1 - 0.007 15.2 0.1 0.0088 14.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Glyco_transf_41 PF13844.6 EGR27131.1 - 0.85 8.0 5.1 1.1 7.6 0.9 2.2 2 1 0 2 2 2 0 Glycosyl transferase family 41 Pkinase PF00069.25 EGR27132.1 - 9e-64 215.4 5.5 9e-64 215.4 5.5 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27132.1 - 1.2e-47 162.4 0.1 2.2e-47 161.5 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27132.1 - 2.8e-09 36.7 0.1 2.5e-06 27.0 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Mit_KHE1 PF10173.9 EGR27132.1 - 4.1 7.4 8.8 8.7 6.4 8.8 1.5 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Kinesin PF00225.23 EGR27133.1 - 6.5e-101 337.6 3.0 6.5e-101 337.6 3.0 2.7 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGR27133.1 - 1.8e-20 73.4 0.2 1.8e-20 73.4 0.2 3.3 2 2 0 2 2 2 1 Microtubule binding IstB_IS21 PF01695.17 EGR27133.1 - 0.08 12.7 0.0 0.2 11.3 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF1493 PF07377.12 EGR27133.1 - 0.43 11.1 3.7 0.9 10.0 2.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF1493) KIF1B PF12423.8 EGR27134.1 - 0.0084 16.5 0.1 0.044 14.2 0.1 2.3 2 0 0 2 2 2 1 Kinesin protein 1B Ribosomal_L19e PF01280.20 EGR27135.1 - 7.5e-58 194.7 12.2 7.5e-58 194.7 12.2 1.7 1 1 1 2 2 2 1 Ribosomal protein L19e NTP_transferase PF00483.23 EGR27136.1 - 1.3e-16 61.0 1.4 4.3e-16 59.3 0.0 2.5 3 0 0 3 3 3 1 Nucleotidyl transferase Hexapep PF00132.24 EGR27136.1 - 0.001 18.7 3.6 0.017 14.8 0.2 2.4 1 1 1 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Phasin PF05597.11 EGR27136.1 - 0.13 12.3 12.1 0.18 11.8 2.7 3.8 2 1 1 3 3 3 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Hexapep_2 PF14602.6 EGR27136.1 - 0.13 12.0 5.6 1.7 8.5 2.7 2.4 1 1 1 2 2 2 0 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.7 EGR27136.1 - 0.14 12.5 0.0 0.23 11.8 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain FHA PF00498.26 EGR27137.1 - 2.1e-10 40.8 0.3 5.4e-10 39.5 0.3 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGR27137.1 - 0.064 13.6 0.1 0.42 10.9 0.1 2.2 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain DUF2393 PF09624.10 EGR27137.1 - 0.1 12.6 9.2 0.15 12.1 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2393) BBS2_N PF14781.6 EGR27137.1 - 0.93 9.4 4.0 1.2 9.1 0.1 2.7 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal Syja_N PF02383.18 EGR27138.1 - 7.3e-64 216.1 13.4 7.3e-64 216.1 13.4 2.2 3 0 0 3 3 3 1 SacI homology domain Exo_endo_phos PF03372.23 EGR27138.1 - 0.034 13.7 0.0 0.06 12.9 0.0 1.4 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family sCache_3_3 PF17202.4 EGR27138.1 - 0.13 12.7 1.0 0.7 10.4 0.0 2.7 3 0 0 3 3 3 0 Single cache domain 3 HD_3 PF13023.6 EGR27138.1 - 0.38 10.7 0.0 0.38 10.7 0.0 2.5 3 0 0 3 3 3 0 HD domain LMBR1 PF04791.16 EGR27139.1 - 1.7e-73 248.3 32.8 1.7e-73 248.3 32.8 1.7 2 0 0 2 2 2 1 LMBR1-like membrane protein Pkinase PF00069.25 EGR27140.1 - 3e-49 167.8 0.3 3.5e-49 167.6 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27140.1 - 5.8e-17 61.8 0.1 7.6e-17 61.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27140.1 - 2e-06 27.3 0.0 3.6e-06 26.5 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGR27140.1 - 0.0096 15.9 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGR27140.1 - 0.069 12.7 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Band_7 PF01145.25 EGR27141.1 - 5.5e-09 36.3 0.0 7.1e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family MEF2_binding PF09047.10 EGR27142.1 - 0.04 13.8 0.5 1.4 8.8 0.1 2.3 2 0 0 2 2 2 0 MEF2 binding HycH PF07450.11 EGR27143.1 - 0.014 15.8 1.9 0.33 11.3 0.3 2.8 2 1 0 2 2 2 0 Formate hydrogenlyase maturation protein HycH Histone PF00125.24 EGR27144.1 - 2.5e-17 63.5 0.9 3.2e-17 63.1 0.9 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGR27144.1 - 1.5e-05 25.1 0.6 2.7e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 EGR27144.1 - 0.0083 15.8 0.1 0.011 15.3 0.1 1.1 1 0 0 1 1 1 1 Replication protein C N-terminal domain AD PF09793.9 EGR27144.1 - 0.0085 16.2 0.4 0.014 15.5 0.4 1.3 1 0 0 1 1 1 1 Anticodon-binding domain Bac_export_2 PF01312.19 EGR27144.1 - 0.033 13.4 0.1 0.035 13.3 0.1 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family TFIID_20kDa PF03847.13 EGR27144.1 - 0.077 13.5 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Arm_3 PF16186.5 EGR27144.1 - 0.15 11.6 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 Atypical Arm repeat PC_rep PF01851.22 EGR27145.1 - 0.003 17.9 9.0 4 8.0 0.0 5.2 4 0 0 4 4 4 3 Proteasome/cyclosome repeat ANAPC1 PF12859.7 EGR27146.1 - 0.1 13.2 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 Snf7 PF03357.21 EGR27147.1 - 1.1e-13 51.1 31.0 1.1e-13 51.1 31.0 1.8 1 1 1 2 2 2 1 Snf7 Uteroglobin PF01099.17 EGR27147.1 - 0.0058 16.9 4.5 0.0058 16.9 4.5 3.3 1 1 3 4 4 4 1 Uteroglobin family kleA_kleC PF17383.2 EGR27147.1 - 0.099 13.0 3.3 0.51 10.7 0.8 2.7 2 0 0 2 2 2 0 Uncharacterized KorC regulated protein A Cyclin_C_2 PF16899.5 EGR27147.1 - 0.53 10.7 4.8 4.8 7.6 3.9 2.6 1 1 1 2 2 2 0 Cyclin C-terminal domain DUF3492 PF11997.8 EGR27147.1 - 5.4 6.7 6.8 9.3 5.9 5.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3492) RCC1 PF00415.18 EGR27148.1 - 8.1e-11 42.4 8.7 4.4e-05 24.0 0.1 5.6 5 0 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR27148.1 - 2e-08 33.8 14.2 0.0014 18.4 0.1 4.3 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat SBBP PF06739.11 EGR27148.1 - 0.012 15.6 0.9 0.038 14.0 0.2 2.2 2 0 0 2 2 2 0 Beta-propeller repeat PEPCK_GTP PF00821.18 EGR27148.1 - 3.6 6.3 7.1 0.19 10.5 0.9 1.8 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain Pet191_N PF10203.9 EGR27150.1 - 3.9e-10 39.9 6.5 6.2e-10 39.2 6.5 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 HEAT_2 PF13646.6 EGR27151.1 - 1.5e-11 44.6 0.0 0.11 12.8 0.0 5.4 5 1 0 6 6 6 3 HEAT repeats HEAT PF02985.22 EGR27151.1 - 9.3e-09 34.8 0.5 0.041 14.1 0.0 6.7 6 0 0 6 6 6 2 HEAT repeat RTP1_C1 PF10363.9 EGR27151.1 - 2.1e-05 24.7 2.2 0.0028 17.8 0.1 5.1 4 2 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EGR27151.1 - 0.0052 17.3 0.0 24 5.6 0.0 4.3 4 0 0 4 4 4 2 HEAT-like repeat CENP-X PF09415.10 EGR27151.1 - 0.041 14.2 3.1 0.93 9.9 0.1 4.3 3 0 0 3 3 3 0 CENP-S associating Centromere protein X Rft-1 PF04506.13 EGR27152.1 - 1.9e-49 168.8 49.0 4.2e-38 131.4 29.1 2.2 2 0 0 2 2 2 2 Rft protein Ubie_methyltran PF01209.18 EGR27153.1 - 2.2e-26 92.7 0.8 3.1e-26 92.1 0.8 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EGR27153.1 - 9.4e-06 25.5 1.0 0.00012 21.9 0.1 2.1 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGR27153.1 - 5.7e-05 23.8 0.1 0.00017 22.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGR27153.1 - 6.3e-05 23.6 0.0 0.00015 22.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGR27153.1 - 0.086 12.8 0.1 0.18 11.8 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase domain ERCC3_RAD25_C PF16203.5 EGR27154.1 - 4.8e-59 199.6 0.9 1.3e-58 198.1 0.9 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EGR27154.1 - 8.1e-18 65.0 2.8 3.8e-17 62.8 1.2 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EGR27154.1 - 1.7e-12 46.7 0.3 2.7e-12 46.1 0.3 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGR27154.1 - 5.9e-12 45.9 1.3 3.1e-11 43.6 0.0 2.9 2 2 2 4 4 4 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 EGR27154.1 - 2.1e-07 30.9 0.8 3.9e-07 30.0 0.8 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase Helicase_C_3 PF13625.6 EGR27154.1 - 1.2e-05 25.5 0.0 2.2e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AChE_tetra PF08674.10 EGR27154.1 - 0.0093 15.6 0.3 0.023 14.4 0.3 1.6 1 0 0 1 1 1 1 Acetylcholinesterase tetramerisation domain Methyltransf_16 PF10294.9 EGR27154.1 - 0.018 14.8 0.2 0.045 13.5 0.0 1.7 1 1 1 2 2 2 0 Lysine methyltransferase zn-ribbon_14 PF16503.5 EGR27156.1 - 3.5e-16 58.4 2.2 3.5e-16 58.4 2.2 3.4 5 0 0 5 5 5 1 Zinc-ribbon ATP_bind_3 PF01171.20 EGR27156.1 - 7.9e-16 58.3 0.0 1.2e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 PP-loop family PAPS_reduct PF01507.19 EGR27156.1 - 0.027 14.5 0.0 0.054 13.5 0.0 1.6 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family zf-UBR PF02207.20 EGR27156.1 - 0.084 13.0 5.6 0.93 9.7 0.7 2.5 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) DUF2616 PF11077.8 EGR27156.1 - 0.092 12.5 4.5 0.23 11.2 0.2 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2616) OrfB_Zn_ribbon PF07282.11 EGR27156.1 - 0.11 12.4 4.9 19 5.3 0.1 3.3 3 0 0 3 3 3 0 Putative transposase DNA-binding domain MMR_HSR1 PF01926.23 EGR27157.1 - 0.0066 16.5 0.1 0.0099 16.0 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EGR27157.1 - 0.016 15.4 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Pkinase PF00069.25 EGR27158.1 - 6.3e-58 196.2 0.4 7.2e-58 196.0 0.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27158.1 - 5.2e-37 127.5 0.1 6.1e-37 127.3 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR27158.1 - 1.6e-05 23.9 0.0 3.7e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 EGR27158.1 - 0.00099 18.8 3.9 0.019 14.6 0.7 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EGR27158.1 - 0.0096 15.5 2.8 0.017 14.8 2.8 1.3 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGR27158.1 - 0.072 12.4 0.4 0.14 11.5 0.4 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TagA PF12561.8 EGR27158.1 - 0.11 12.9 0.5 0.21 12.0 0.5 1.4 1 0 0 1 1 1 0 ToxR activated gene A lipoprotein domain MORN PF02493.20 EGR27159.1 - 2.7e-58 190.5 66.8 9.2e-08 31.6 1.2 10.2 10 0 0 10 10 10 10 MORN repeat ADK PF00406.22 EGR27160.1 - 4.2e-43 147.1 15.0 8.6e-35 120.1 0.1 6.5 5 3 0 5 5 5 3 Adenylate kinase AAA_17 PF13207.6 EGR27160.1 - 3.5e-29 102.0 9.9 7.3e-20 71.8 0.1 6.4 6 1 0 6 6 5 3 AAA domain AAA_18 PF13238.6 EGR27160.1 - 5.2e-21 75.6 0.4 3.1e-09 37.5 0.0 4.6 3 1 0 3 3 3 3 AAA domain AAA_33 PF13671.6 EGR27160.1 - 1.7e-13 50.9 0.0 0.002 18.3 0.0 4.2 3 1 0 3 3 3 3 AAA domain AAA PF00004.29 EGR27160.1 - 2e-10 41.2 0.0 0.0074 16.7 0.0 4.6 3 1 1 4 4 4 2 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EGR27160.1 - 5.7e-10 38.8 0.0 0.018 14.3 0.0 3.4 3 0 0 3 3 3 3 Zeta toxin AAA_28 PF13521.6 EGR27160.1 - 1e-08 35.6 0.0 0.00039 20.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EGR27160.1 - 3.5e-08 33.8 2.0 0.055 13.9 0.1 5.0 4 0 0 4 4 4 2 RNA helicase Rad17 PF03215.15 EGR27160.1 - 7.1e-08 32.6 3.2 0.012 15.6 0.0 5.4 5 0 0 5 5 5 1 Rad17 P-loop domain NB-ARC PF00931.22 EGR27160.1 - 2.7e-07 30.0 0.4 2 7.5 0.0 5.1 4 1 1 5 5 5 2 NB-ARC domain SKI PF01202.22 EGR27160.1 - 2.3e-06 27.8 0.3 0.0014 18.8 0.0 4.3 4 0 0 4 4 3 1 Shikimate kinase AAA_22 PF13401.6 EGR27160.1 - 4.6e-06 27.0 0.0 0.16 12.2 0.0 3.7 3 0 0 3 3 3 2 AAA domain ABC_tran PF00005.27 EGR27160.1 - 1.9e-05 25.2 0.0 0.0052 17.3 0.0 4.1 3 0 0 3 3 3 1 ABC transporter RuvB_N PF05496.12 EGR27160.1 - 0.00013 21.7 0.0 5.3 6.8 0.0 3.9 4 0 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain Cytidylate_kin PF02224.18 EGR27160.1 - 0.00019 21.3 0.0 0.7 9.6 0.0 3.1 2 0 0 2 2 2 2 Cytidylate kinase AAA_16 PF13191.6 EGR27160.1 - 0.00025 21.5 0.0 1.5 9.2 0.0 3.9 4 0 0 4 4 3 1 AAA ATPase domain AAA_5 PF07728.14 EGR27160.1 - 0.00031 20.8 0.0 0.79 9.7 0.0 3.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Hydin_ADK PF17213.3 EGR27160.1 - 0.0029 17.9 0.1 0.045 14.0 0.0 2.9 4 0 0 4 4 3 1 Hydin Adenylate kinase-like domain RsgA_GTPase PF03193.16 EGR27160.1 - 0.0085 16.0 0.0 0.75 9.7 0.0 3.3 3 0 0 3 3 3 1 RsgA GTPase Sigma54_activ_2 PF14532.6 EGR27160.1 - 0.015 15.5 1.5 1 9.5 0.0 4.0 5 0 0 5 5 3 0 Sigma-54 interaction domain CPT PF07931.12 EGR27160.1 - 0.015 15.2 0.0 11 5.9 0.0 3.2 3 0 0 3 3 2 0 Chloramphenicol phosphotransferase-like protein AAA_19 PF13245.6 EGR27160.1 - 0.019 15.3 0.0 6.7 7.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 EGR27160.1 - 0.022 14.8 17.8 0.092 12.8 1.6 5.6 4 2 1 5 5 5 0 AAA domain Ploopntkinase3 PF18751.1 EGR27160.1 - 0.031 14.2 0.0 2.1 8.2 0.0 2.8 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 Thymidylate_kin PF02223.17 EGR27160.1 - 0.048 13.3 6.3 7.4 6.2 0.0 4.6 5 0 0 5 5 4 0 Thymidylate kinase NTPase_1 PF03266.15 EGR27160.1 - 0.069 13.1 0.2 30 4.5 0.0 3.4 4 0 0 4 4 3 0 NTPase SRP54 PF00448.22 EGR27160.1 - 0.11 12.2 0.0 8.7 5.9 0.0 3.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain Na_H_Exchanger PF00999.21 EGR27161.1 - 6e-49 166.8 40.5 9.7e-49 166.1 40.5 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family cNMP_binding PF00027.29 EGR27161.1 - 0.00034 20.6 0.0 0.0013 18.8 0.0 2.1 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain PHO4 PF01384.20 EGR27161.1 - 0.024 13.7 2.8 0.06 12.4 0.3 2.3 2 1 0 2 2 2 0 Phosphate transporter family Vert_HS_TF PF06546.11 EGR27161.1 - 0.18 11.4 0.1 0.32 10.6 0.1 1.3 1 0 0 1 1 1 0 Vertebrate heat shock transcription factor Metallophos PF00149.28 EGR27162.1 - 2e-34 119.9 0.4 2.6e-34 119.5 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGR27162.1 - 0.00038 20.8 1.1 0.0012 19.2 1.1 1.9 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain TAD2 PF18521.1 EGR27162.1 - 0.1 12.6 0.7 0.25 11.4 0.7 1.6 1 0 0 1 1 1 0 Transactivation domain 2 RIO1 PF01163.22 EGR27163.1 - 6.4e-47 159.6 8.1 9.2e-46 155.8 1.1 2.5 2 0 0 2 2 2 2 RIO1 family Pkinase PF00069.25 EGR27163.1 - 2.3e-43 148.5 6.4 6.1e-38 130.7 1.1 2.5 2 1 0 2 2 2 2 Protein kinase domain Rio2_N PF09202.11 EGR27163.1 - 8.7e-24 83.5 5.5 1.6e-21 76.3 4.9 3.2 2 1 0 2 2 2 1 Rio2, N-terminal Pkinase_Tyr PF07714.17 EGR27163.1 - 6.8e-20 71.4 0.4 3.5e-17 62.5 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 EGR27163.1 - 3.3e-10 39.7 0.3 0.00024 20.5 0.1 3.2 2 1 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR27163.1 - 8e-08 32.5 0.0 0.016 15.1 0.0 3.2 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EGR27163.1 - 3.6e-06 26.5 0.0 0.00044 19.7 0.0 2.5 2 0 0 2 2 2 1 Kinase-like DUF5523 PF17661.1 EGR27163.1 - 0.2 11.3 10.2 0.31 10.7 10.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5523) CDC45 PF02724.14 EGR27163.1 - 0.21 9.8 8.7 0.32 9.2 8.7 1.2 1 0 0 1 1 1 0 CDC45-like protein MORN PF02493.20 EGR27164.1 - 1.1e-70 229.5 111.1 2.6e-07 30.1 3.8 14.3 14 0 0 14 14 14 14 MORN repeat DUF3048_C PF17479.2 EGR27164.1 - 0.003 17.9 31.7 1.4 9.3 0.3 6.3 2 2 4 6 6 6 6 Protein of unknown function (DUF3048) C-terminal domain Pkinase PF00069.25 EGR27165.1 - 4.8e-66 222.8 0.2 7e-66 222.3 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27165.1 - 3.8e-37 128.0 0.0 4.9e-37 127.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR27165.1 - 0.00033 19.6 0.0 0.00064 18.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EGR27165.1 - 0.00091 18.9 0.4 0.036 13.7 0.1 2.4 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EGR27165.1 - 0.0015 17.9 0.0 0.004 16.5 0.0 1.7 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EGR27165.1 - 0.081 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGR27165.1 - 0.1 12.0 0.1 0.16 11.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L4 PF00573.22 EGR27166.1 - 8.3e-33 113.7 0.4 1.6e-32 112.7 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EGR27166.1 - 1.6e-22 79.3 3.7 1.6e-22 79.3 3.7 1.9 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain YbjM PF11045.8 EGR27166.1 - 0.1 12.8 0.7 0.76 10.0 1.0 2.0 2 0 0 2 2 2 0 Putative inner membrane protein of Enterobacteriaceae YTH PF04146.15 EGR27167.1 - 3.9e-26 92.0 11.2 4.3e-26 91.8 2.3 3.2 2 1 0 2 2 2 1 YT521-B-like domain CLZ PF16526.5 EGR27168.1 - 0.0054 17.1 2.0 0.019 15.3 1.1 2.4 1 1 0 1 1 1 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Jnk-SapK_ap_N PF09744.9 EGR27168.1 - 0.097 12.9 6.4 0.27 11.4 6.4 1.7 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Edc3_linker PF16598.5 EGR27168.1 - 0.17 12.6 3.2 18 6.1 0.1 3.2 3 0 0 3 3 3 0 Linker region of enhancer of mRNA-decapping protein 3 DUF4407 PF14362.6 EGR27168.1 - 0.58 9.4 2.7 0.82 9.0 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Syntaxin_2 PF14523.6 EGR27168.1 - 1.1 9.7 12.1 3.5 8.1 12.1 1.9 1 0 0 1 1 1 0 Syntaxin-like protein Pkinase PF00069.25 EGR27169.1 - 3.1e-52 177.5 3.6 6.7e-43 147.0 0.1 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27169.1 - 4.1e-35 121.3 0.7 5.4e-34 117.6 0.7 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27169.1 - 2.4e-08 33.7 0.5 3.8e-08 33.0 0.5 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR27169.1 - 8.4e-07 28.1 0.1 1.3e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase RRM_1 PF00076.22 EGR27170.1 - 0.0019 18.0 0.1 0.6 10.0 0.0 3.6 3 1 0 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Copine PF07002.16 EGR27171.1 - 3.5e-64 216.2 0.1 5e-64 215.7 0.1 1.2 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 EGR27171.1 - 2.7e-05 24.4 0.0 4.7e-05 23.6 0.0 1.6 1 1 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 EGR27171.1 - 0.084 13.1 0.1 0.17 12.1 0.1 1.7 1 0 0 1 1 1 0 von Willebrand factor type A domain Cse1 PF08506.10 EGR27172.1 - 8.3e-17 61.1 9.4 1.1e-16 60.7 2.0 3.6 3 0 0 3 3 3 2 Cse1 CAS_CSE1 PF03378.15 EGR27172.1 - 1.9e-14 53.1 18.6 1.9e-14 53.1 18.6 3.0 3 2 0 3 3 3 1 CAS/CSE protein, C-terminus Pkinase PF00069.25 EGR27173.1 - 1.7e-55 188.2 3.5 1.7e-55 188.2 3.5 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27173.1 - 3.6e-33 115.0 2.9 1.2e-32 113.2 2.9 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR27173.1 - 0.00023 20.1 0.1 0.00023 20.1 0.1 2.8 3 0 0 3 3 3 2 Fungal protein kinase APH PF01636.23 EGR27173.1 - 0.043 13.7 0.1 0.076 12.9 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Zip PF02535.22 EGR27173.1 - 0.67 9.1 4.2 0.89 8.7 4.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EGR27173.1 - 2.4 6.8 7.4 3.5 6.3 7.4 1.3 1 0 0 1 1 1 0 Presenilin GF_recep_IV PF14843.6 EGR27174.1 - 4.4e-61 204.5 1001.5 5.1e-08 32.8 37.2 34.8 5 4 29 34 34 34 29 Growth factor receptor domain IV VSP PF03302.13 EGR27174.1 - 9.2e-55 186.1 965.0 1.1e-05 24.5 40.6 45.5 4 4 37 42 42 42 38 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EGR27174.1 - 0.0043 17.2 26.0 0.0043 17.2 26.0 38.5 1 1 44 46 46 46 14 Furin-like repeat, cysteine-rich Bac_A_amyl_C PF18612.1 EGR27174.1 - 0.0057 16.4 14.0 23 4.8 0.0 8.7 11 0 0 11 11 11 2 Bacterial Alpha amylase C-terminal domain SNF2_N PF00176.23 EGR27175.1 - 3.3e-71 239.8 1.9 4.9e-71 239.3 1.9 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGR27175.1 - 5.4e-20 71.8 0.1 1.1e-18 67.6 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGR27175.1 - 1.9e-12 47.5 0.1 1.9e-12 47.5 0.1 2.8 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGR27175.1 - 1.4e-05 25.0 0.0 4.2e-05 23.4 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EGR27175.1 - 0.00032 20.5 0.0 0.00091 18.9 0.0 1.8 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF3298 PF11738.8 EGR27175.1 - 4 8.5 7.0 2.2 9.4 2.5 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF3298) Ribosomal_L27A PF00828.19 EGR27178.1 - 2.8e-24 86.2 0.1 3.7e-24 85.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A NDK PF00334.19 EGR27179.1 - 6.7e-70 233.3 0.1 1.8e-35 121.9 0.0 2.1 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 EGR27179.1 - 5.9e-06 26.0 1.1 2.4e-05 24.1 1.1 2.0 1 1 0 1 1 1 1 DUF1126 PH-like domain DUF3908 PF13048.6 EGR27179.1 - 1.2 9.4 8.7 0.16 12.2 1.2 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3908) CAF1C_H4-bd PF12265.8 EGR27180.1 - 2.5e-17 62.9 2.6 7.9e-17 61.3 2.0 2.2 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGR27180.1 - 2.3e-12 47.2 6.6 0.012 16.4 0.0 5.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR27180.1 - 0.0019 18.5 0.9 0.13 12.6 0.2 2.8 1 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain ox_reductase_C PF08635.10 EGR27180.1 - 0.05 13.2 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain Ntox50 PF15542.6 EGR27181.1 - 0.082 13.7 6.7 1.8 9.4 6.7 2.3 1 1 1 2 2 2 0 Bacterial toxin 50 DUF3736 PF12540.8 EGR27181.1 - 0.083 13.0 2.4 0.087 12.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3736) DUF4407 PF14362.6 EGR27181.1 - 1 8.6 7.0 1.2 8.4 7.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Phage_Gp23 PF10669.9 EGR27181.1 - 1.8 8.9 16.2 1.7 9.0 15.3 1.4 1 1 0 1 1 1 0 Protein gp23 (Bacteriophage A118) MRNIP PF15749.5 EGR27181.1 - 8.2 7.2 15.3 14 6.4 9.1 2.1 1 1 1 2 2 2 0 MRN-interacting protein GBP PF02263.19 EGR27182.1 - 5.5e-65 219.2 0.0 5.5e-65 219.2 0.0 5.6 2 1 1 5 5 5 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 EGR27182.1 - 1.2e-17 64.3 38.5 1.2e-17 64.3 38.5 6.8 1 1 7 8 8 8 1 Guanylate-binding protein, C-terminal domain Beta_elim_lyase PF01212.21 EGR27183.1 - 3.9e-66 223.3 0.0 4.6e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EGR27183.1 - 0.00011 20.9 0.0 0.00016 20.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme OKR_DC_1 PF01276.20 EGR27183.1 - 0.0032 16.3 0.0 0.0063 15.3 0.0 1.4 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain Aminotran_1_2 PF00155.21 EGR27183.1 - 0.011 15.0 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class I and II DivIC PF04977.15 EGR27183.1 - 0.042 13.6 0.2 3.2 7.6 0.0 2.5 2 0 0 2 2 2 0 Septum formation initiator Pyridoxal_deC PF00282.19 EGR27183.1 - 0.074 11.8 0.0 0.11 11.2 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Pkinase PF00069.25 EGR27184.1 - 1.1e-62 211.8 2.3 1.6e-62 211.3 2.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27184.1 - 7.7e-43 146.6 0.4 1.3e-42 145.9 0.4 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27184.1 - 9.4e-06 25.1 0.1 2.6e-05 23.7 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR27184.1 - 1.4e-05 24.1 0.2 2.2e-05 23.4 0.2 1.3 1 0 0 1 1 1 1 Fungal protein kinase Roc PF08477.13 EGR27184.1 - 0.047 13.9 0.5 0.28 11.4 0.1 2.4 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Kdo PF06293.14 EGR27184.1 - 0.085 12.2 4.3 0.035 13.5 1.5 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family VID27 PF08553.10 EGR27186.1 - 7.6e-71 239.0 8.9 1.1e-70 238.5 8.9 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain WD40 PF00400.32 EGR27186.1 - 0.0022 18.8 0.0 0.17 12.8 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat DUF4667 PF15700.5 EGR27186.1 - 2.3 8.3 12.2 0.84 9.7 9.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) OrfB_IS605 PF01385.19 EGR27186.1 - 8.5 6.6 8.9 0.2 11.9 0.9 2.3 2 0 0 2 2 2 0 Probable transposase ThiF PF00899.21 EGR27187.1 - 3.6e-63 213.2 1.9 1.2e-41 142.7 0.1 2.2 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EGR27187.1 - 5.3e-54 183.8 8.5 5.3e-54 183.8 8.5 2.3 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 EGR27187.1 - 1.9e-23 82.4 3.8 6.8e-23 80.7 3.8 2.1 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 EGR27187.1 - 1.3e-19 70.7 0.2 1.3e-19 70.7 0.2 3.9 4 0 0 4 4 4 1 Ubiquitin fold domain E1_4HB PF16191.5 EGR27187.1 - 1e-13 51.2 3.0 1.1e-13 51.2 0.5 2.5 3 0 0 3 3 3 1 Ubiquitin-activating enzyme E1 four-helix bundle MutS_IV PF05190.18 EGR27187.1 - 4.4 7.7 8.6 16 6.0 5.2 3.4 2 0 0 2 2 2 0 MutS family domain IV GDYXXLXY PF14345.6 EGR27188.1 - 0.1 12.4 0.2 12 5.6 0.0 2.3 2 0 0 2 2 2 0 GDYXXLXY protein CcmF_C PF16327.5 EGR27189.1 - 0.0029 16.9 1.7 0.004 16.5 1.7 1.2 1 0 0 1 1 1 1 Cytochrome c-type biogenesis protein CcmF C-terminal DUF5313 PF17240.2 EGR27189.1 - 2 8.8 9.4 0.45 11.0 5.6 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5313) SNF2_N PF00176.23 EGR27190.1 - 8.1e-56 189.2 4.6 8.1e-56 189.2 4.6 2.0 2 1 0 2 2 2 1 SNF2 family N-terminal domain Bromodomain PF00439.25 EGR27190.1 - 1.4e-11 44.3 1.7 1.4e-11 44.3 1.7 2.6 2 0 0 2 2 2 1 Bromodomain Chromo PF00385.24 EGR27190.1 - 1.9e-11 43.7 9.7 9.1e-06 25.5 2.2 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 EGR27190.1 - 4.2e-11 43.2 0.0 4.2e-11 43.2 0.0 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGR27190.1 - 4.3e-08 33.1 0.0 1.5e-07 31.4 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGR27190.1 - 0.0013 19.0 1.5 0.4 11.0 0.0 3.4 3 0 0 3 3 3 1 AAA domain DUF1894 PF08979.11 EGR27190.1 - 0.1 13.0 2.2 0.54 10.6 2.2 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1894) Peptidase_C37 PF05416.12 EGR27190.1 - 0.1 11.1 6.7 0.23 9.9 6.7 1.5 1 0 0 1 1 1 0 Southampton virus-type processing peptidase Tiam_CC_Ex PF18385.1 EGR27190.1 - 0.22 11.9 3.1 0.15 12.5 0.5 2.2 2 0 0 2 2 2 0 T-lymphoma invasion and metastasis CC-Ex domain adh_short PF00106.25 EGR27191.1 - 1.6e-11 44.0 0.7 3e-11 43.2 0.2 1.6 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGR27191.1 - 2.3e-08 33.9 0.2 1.2e-07 31.5 0.1 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGR27191.1 - 5.5e-05 23.1 0.2 0.0001 22.3 0.2 1.3 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 EGR27191.1 - 0.0051 16.2 0.1 0.0095 15.3 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EGR27191.1 - 0.067 12.5 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain UDPG_MGDP_dh_N PF03721.14 EGR27191.1 - 0.1 12.1 0.1 0.16 11.6 0.1 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EGR27191.1 - 0.13 12.2 0.1 0.29 11.0 0.1 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TFIIA_gamma_N PF02268.16 EGR27192.1 - 0.038 14.0 0.2 0.2 11.7 0.0 2.3 2 0 0 2 2 2 0 Transcription initiation factor IIA, gamma subunit, helical domain PDEase_I PF00233.19 EGR27193.1 - 1.4e-64 218.1 8.8 1.4e-64 218.1 8.8 2.1 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Vps35 PF03635.17 EGR27194.1 - 9.1e-207 689.0 54.8 9.1e-207 689.0 54.8 2.0 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 35 Telomere_reg-2 PF10193.9 EGR27194.1 - 0.098 13.1 12.5 1.9 8.9 1.7 4.3 3 0 0 3 3 3 0 Telomere length regulation protein Pkinase PF00069.25 EGR27195.1 - 1.7e-53 181.7 2.0 3.1e-53 180.8 2.0 1.4 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 EGR27195.1 - 3.9e-28 97.4 0.2 8.8e-16 57.8 0.1 3.6 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 EGR27195.1 - 7.8e-23 81.1 0.2 1.2e-22 80.4 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR27195.1 - 7.3e-06 25.0 0.0 1.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGR27195.1 - 0.009 15.4 0.2 0.029 13.7 0.2 1.9 1 1 0 1 1 1 1 Kinase-like Ribosomal_S8e PF01201.22 EGR27195.1 - 0.033 14.4 0.9 0.081 13.1 0.9 1.6 1 0 0 1 1 1 0 Ribosomal protein S8e Meis_PKNOX_N PF16493.5 EGR27195.1 - 0.079 13.3 1.0 0.29 11.5 1.0 2.0 1 0 0 1 1 1 0 N-terminal of Homeobox Meis and PKNOX1 CitMHS PF03600.16 EGR27195.1 - 0.16 11.2 0.4 0.27 10.4 0.4 1.3 1 0 0 1 1 1 0 Citrate transporter Ribosomal_S13 PF00416.22 EGR27195.1 - 1.3 9.4 4.2 17 5.8 0.1 3.1 3 0 0 3 3 3 0 Ribosomal protein S13/S18 Pkinase PF00069.25 EGR27196.1 - 3.1e-21 75.9 2.4 8.2e-21 74.5 2.4 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27196.1 - 1.7e-16 60.3 0.8 1.7e-16 60.3 0.8 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase MRP-S33 PF08293.11 EGR27196.1 - 4 7.7 7.1 0.58 10.4 1.6 2.5 3 0 0 3 3 3 0 Mitochondrial ribosomal subunit S27 CDC50 PF03381.15 EGR27197.1 - 3e-84 282.9 4.5 4.1e-84 282.4 4.5 1.2 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF4064 PF13273.6 EGR27197.1 - 0.0057 16.9 9.0 0.23 11.7 0.5 3.2 3 0 0 3 3 3 2 Protein of unknown function (DUF4064) Cadherin_C_2 PF16492.5 EGR27197.1 - 0.012 16.3 2.2 8.6 7.2 0.0 3.1 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal Claudin_2 PF13903.6 EGR27197.1 - 0.075 12.8 1.6 6.6 6.4 0.1 2.4 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF3185 PF11381.8 EGR27197.1 - 0.23 11.5 3.8 11 6.1 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) MR_MLE_C PF13378.6 EGR27198.1 - 5.1e-46 157.0 0.0 7.1e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like DHDPS PF00701.22 EGR27198.1 - 1.6e-41 141.9 0.0 3.8e-41 140.7 0.0 1.6 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family MR_MLE_N PF02746.16 EGR27198.1 - 0.012 15.8 0.0 0.034 14.3 0.0 1.8 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain adh_short PF00106.25 EGR27199.1 - 1.6e-31 109.3 0.0 2.2e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGR27199.1 - 3.6e-18 66.0 0.0 4.7e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EGR27199.1 - 0.00076 18.9 0.1 0.016 14.6 0.1 2.1 1 1 1 2 2 2 1 Fungal family of unknown function (DUF1776) KR PF08659.10 EGR27199.1 - 0.073 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 KR domain Ank_2 PF12796.7 EGR27200.1 - 2.2e-33 114.7 10.9 2.7e-15 56.7 1.5 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGR27200.1 - 1.4e-25 89.3 5.6 6.4e-10 39.4 0.0 3.4 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGR27200.1 - 1.5e-23 82.1 5.6 1.5e-07 31.6 0.0 4.6 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 EGR27200.1 - 3.9e-23 79.0 1.5 3.2e-05 24.0 0.0 4.4 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EGR27200.1 - 1.8e-22 79.1 10.0 1.7e-10 40.9 0.2 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Pyr_redox_2 PF07992.14 EGR27201.1 - 1.5e-09 37.5 0.0 1.5e-09 37.5 0.0 3.5 3 1 1 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGR27201.1 - 6.5e-05 23.4 0.3 6.5e-05 23.4 0.3 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase RasGEF PF00617.19 EGR27202.1 - 1.5e-07 31.8 7.5 1.5e-07 31.8 7.5 2.2 2 1 0 2 2 2 1 RasGEF domain Pyr_redox_2 PF07992.14 EGR27203.1 - 1e-13 51.2 0.0 8.3e-08 31.8 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGR27203.1 - 0.078 13.6 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGR27203.1 - 0.12 11.6 0.2 1.4 8.1 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DUF572 PF04502.13 EGR27204.1 - 5.5e-64 216.9 14.6 6.2e-64 216.7 14.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-FCS PF06467.14 EGR27204.1 - 0.0026 17.7 2.7 1.1 9.2 0.1 2.4 2 0 0 2 2 2 2 MYM-type Zinc finger with FCS sequence motif Radical_SAM PF04055.21 EGR27204.1 - 0.028 14.8 0.7 0.044 14.2 0.1 1.6 2 0 0 2 2 2 0 Radical SAM superfamily HypA PF01155.19 EGR27204.1 - 0.042 13.9 0.1 5 7.2 0.0 2.4 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA FERM_M PF00373.18 EGR27204.1 - 0.24 11.8 2.3 0.51 10.8 2.3 1.7 1 1 0 1 1 1 0 FERM central domain RNA_pol_N PF01194.17 EGR27204.1 - 0.42 11.0 3.9 0.81 10.0 0.5 2.5 2 1 0 2 2 2 0 RNA polymerases N / 8 kDa subunit zf-ribbon_3 PF13248.6 EGR27204.1 - 0.67 9.5 0.0 0.67 9.5 0.0 2.4 3 0 0 3 3 3 0 zinc-ribbon domain DSPc PF00782.20 EGR27205.1 - 1e-25 90.1 1.2 1e-25 90.1 1.2 2.1 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EGR27205.1 - 4.6e-05 23.6 1.1 0.00016 21.8 0.1 2.2 2 1 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 EGR27205.1 - 0.00011 21.9 0.3 0.00011 21.9 0.3 2.3 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EGR27205.1 - 0.00019 21.4 0.1 0.00077 19.5 0.0 2.0 2 1 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGR27205.1 - 0.0012 18.5 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EGR27205.1 - 0.0039 17.5 0.0 0.01 16.1 0.0 1.7 1 0 0 1 1 1 1 Rit1 DUSP-like domain DUF5033 PF16436.5 EGR27205.1 - 0.028 14.4 0.4 0.062 13.2 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5033) TTL PF03133.15 EGR27206.1 - 1.1e-74 251.3 12.2 1.1e-74 251.3 12.2 2.2 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 EGR27206.1 - 9.4e-08 31.6 0.3 0.0033 16.7 0.0 3.7 3 1 0 3 3 3 3 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 EGR27206.1 - 7.5e-06 25.4 12.2 0.0011 18.3 0.0 4.4 3 2 1 4 4 4 3 YheC/D like ATP-grasp Pkinase PF00069.25 EGR27207.1 - 2.3e-78 263.2 0.2 2.9e-78 262.9 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27207.1 - 3.4e-35 121.6 0.0 5.4e-35 120.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR27207.1 - 0.00014 21.0 0.5 0.00027 20.0 0.5 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGR27207.1 - 0.00084 18.7 0.0 0.003 16.9 0.0 1.8 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 EGR27207.1 - 0.0032 17.1 2.1 0.18 11.4 0.0 2.9 2 1 1 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGR27207.1 - 0.017 15.0 0.0 0.094 12.6 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family XRN1_D2_D3 PF18334.1 EGR27207.1 - 0.031 14.5 0.1 8.5 6.7 0.0 3.2 3 0 0 3 3 3 0 Exoribonuclease Xrn1 D2/D3 domain Sulfotransfer_1 PF00685.27 EGR27207.1 - 0.87 9.0 6.0 17 4.8 0.1 3.1 2 1 1 3 3 3 0 Sulfotransferase domain SNF2_N PF00176.23 EGR27208.1 - 3.1e-52 177.4 1.9 8.2e-52 176.1 1.9 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGR27208.1 - 1.4e-16 60.8 0.1 1.4e-16 60.8 0.1 3.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 EGR27208.1 - 4.2e-12 46.0 1.4 1.8e-11 43.9 0.4 2.8 2 0 0 2 2 2 1 Bromodomain DEAD PF00270.29 EGR27208.1 - 3.5e-05 23.7 0.0 0.00035 20.4 0.0 2.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase zf-HC5HC2H PF13771.6 EGR27208.1 - 0.00074 19.7 44.9 0.066 13.5 11.1 4.2 1 1 2 3 3 3 3 PHD-like zinc-binding domain PHD PF00628.29 EGR27208.1 - 0.012 15.5 38.9 0.013 15.3 6.3 4.3 2 1 0 3 3 3 0 PHD-finger AAA_22 PF13401.6 EGR27208.1 - 0.02 15.2 0.2 0.19 12.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain zf-HC5HC2H_2 PF13832.6 EGR27208.1 - 3.4 7.9 40.9 2.9 8.1 8.1 4.4 1 1 2 3 3 3 0 PHD-zinc-finger like domain WD40 PF00400.32 EGR27209.1 - 5.4e-17 61.9 13.4 9.3e-06 26.3 0.0 5.7 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR27209.1 - 1.8e-13 50.6 2.7 1.2e-05 25.5 0.1 4.1 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGR27209.1 - 0.017 14.5 0.1 4.1 6.6 0.1 2.5 2 0 0 2 2 2 0 WD40-like domain RAB3GAP2_N PF14655.6 EGR27209.1 - 0.022 14.0 0.0 0.044 13.1 0.0 1.5 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Nbas_N PF15492.6 EGR27209.1 - 0.033 13.5 0.0 1.3 8.3 0.0 2.5 1 1 1 2 2 2 0 Neuroblastoma-amplified sequence, N terminal WD40 PF00400.32 EGR27210.1 - 1.7e-17 63.4 5.8 2.8e-05 24.8 0.3 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR27210.1 - 3.2e-06 27.4 0.1 0.79 10.1 0.0 5.0 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF4860 PF16152.5 EGR27211.1 - 0.025 14.4 0.8 0.47 10.4 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4860) Guanylate_cyc PF00211.20 EGR27212.1 - 1e-12 48.1 0.1 2.8e-12 46.6 0.1 1.7 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Raf1_N PF18578.1 EGR27212.1 - 0.074 13.5 0.2 0.18 12.3 0.2 1.6 1 0 0 1 1 1 0 Rubisco accumulation factor 1 alpha helical domain UCH_C PF18031.1 EGR27212.1 - 0.62 10.0 4.3 2.4 8.1 1.0 2.6 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolases DUF667 PF05018.13 EGR27213.1 - 9.4e-73 243.9 8.0 2.7e-72 242.4 8.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF667) ETRAMP PF09716.10 EGR27213.1 - 0.018 15.1 8.1 0.018 15.1 8.1 4.3 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) CsiV PF10972.8 EGR27213.1 - 0.039 13.7 1.5 0.068 12.9 1.5 1.4 1 0 0 1 1 1 0 Peptidoglycan-binding protein, CsiV WD40 PF00400.32 EGR27214.1 - 1.2e-24 86.0 11.6 1.4e-07 32.0 0.0 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR27214.1 - 0.00026 21.2 2.5 4.4 7.7 0.6 4.7 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGR27214.1 - 0.014 14.8 4.3 1.2 8.4 0.2 2.9 1 1 0 2 2 2 0 WD40-like domain B_lectin PF01453.24 EGR27214.1 - 0.47 11.0 2.8 0.8 10.3 0.3 2.6 3 0 0 3 3 3 0 D-mannose binding lectin tRNA-synt_1c PF00749.21 EGR27215.1 - 3.2e-50 170.8 2.7 4e-50 170.5 2.7 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Reo_sigmaC_M PF17750.1 EGR27215.1 - 0.65 9.9 3.3 0.26 11.1 0.4 1.8 2 0 0 2 2 2 0 Reovirus sigma C capsid protein triple beta spiral MutS_V PF00488.21 EGR27216.1 - 7.6e-51 172.8 0.0 1.5e-50 171.9 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGR27216.1 - 5.2e-26 92.1 0.9 8.8e-26 91.3 0.9 1.4 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 EGR27216.1 - 0.00041 20.6 4.7 0.0018 18.6 4.2 2.4 1 1 1 2 2 2 1 MutS family domain IV EFP PF01132.20 EGR27216.1 - 0.00079 19.4 0.0 0.0049 16.9 0.0 2.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain K-box PF01486.17 EGR27216.1 - 5.2 7.3 8.6 4.1 7.6 0.9 3.7 4 1 0 4 4 4 0 K-box region Bunya_G2 PF03563.13 EGR27217.1 - 5.8 6.1 11.6 6.2 6.0 11.6 1.1 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 Pkinase PF00069.25 EGR27218.1 - 1.8e-44 152.1 0.0 1.8e-44 152.1 0.0 3.0 2 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27218.1 - 2.2e-33 115.6 0.0 5.5e-33 114.3 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EGR27218.1 - 8.8e-12 45.3 12.8 1.2e-08 35.2 1.2 3.7 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 EGR27218.1 - 9.7e-11 41.4 6.7 7.5e-05 22.5 1.8 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR27218.1 - 5.5e-10 38.1 18.0 3e-06 26.4 1.7 4.7 4 1 1 5 5 5 2 EF hand EF-hand_6 PF13405.6 EGR27218.1 - 3.8e-09 35.8 14.9 5.3e-05 22.8 0.7 5.1 4 1 0 4 4 4 2 EF-hand domain p25-alpha PF05517.12 EGR27218.1 - 0.0001 22.5 18.3 0.00085 19.5 4.6 2.9 2 1 1 3 3 3 2 p25-alpha EF-hand_5 PF13202.6 EGR27218.1 - 0.00054 19.3 6.5 0.025 14.1 1.6 3.8 3 0 0 3 3 3 1 EF hand RST PF12174.8 EGR27218.1 - 0.0048 16.8 13.5 0.018 14.9 1.2 3.8 3 1 1 4 4 4 2 RCD1-SRO-TAF4 (RST) plant domain Bro-N PF02498.17 EGR27218.1 - 0.0072 17.0 0.6 0.0072 17.0 0.6 2.9 2 2 1 3 3 3 1 BRO family, N-terminal domain EF-hand_9 PF14658.6 EGR27218.1 - 0.0073 16.6 0.2 0.33 11.3 0.0 2.6 2 0 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 EGR27218.1 - 0.024 14.6 2.9 0.024 14.6 2.9 3.4 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand DUF4946 PF16304.5 EGR27218.1 - 0.6 9.8 4.3 1.3 8.7 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4946) MSC PF09402.10 EGR27218.1 - 1.2 8.5 18.3 0.038 13.5 4.5 2.5 1 1 1 2 2 2 0 Man1-Src1p-C-terminal domain SPARC_Ca_bdg PF10591.9 EGR27218.1 - 1.3 9.4 18.5 0.042 14.2 6.6 2.9 2 2 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Hydrolase_4 PF12146.8 EGR27219.1 - 1.4e-10 40.9 0.0 2.2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR27219.1 - 2.1e-10 40.7 0.1 1.3e-09 38.1 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.16 EGR27219.1 - 2.5e-05 23.7 0.0 0.00022 20.7 0.0 2.4 3 0 0 3 3 3 1 Partial alpha/beta-hydrolase lipase region Peptidase_S15 PF02129.18 EGR27219.1 - 0.013 15.1 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) VWA PF00092.28 EGR27219.1 - 0.03 14.6 3.3 11 6.2 1.1 3.0 1 1 1 3 3 3 0 von Willebrand factor type A domain ABC2_membrane PF01061.24 EGR27220.1 - 1.7e-31 109.3 30.7 1.7e-31 109.3 30.7 1.6 1 1 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGR27220.1 - 8.8e-19 68.4 0.2 8.8e-19 68.4 0.2 1.9 2 0 0 2 2 2 1 ABC transporter AAA_18 PF13238.6 EGR27220.1 - 0.093 13.3 0.4 0.19 12.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGR27220.1 - 0.14 12.5 0.0 0.26 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain HEAT PF02985.22 EGR27222.1 - 1.2e-16 59.4 0.0 0.028 14.7 0.0 10.1 12 0 0 12 12 11 3 HEAT repeat HEAT_2 PF13646.6 EGR27222.1 - 2.8e-09 37.2 0.0 0.2 12.1 0.0 5.3 4 1 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 EGR27222.1 - 1.4e-06 28.7 0.0 0.028 14.9 0.0 4.4 5 0 0 5 5 5 2 HEAT-like repeat RTP1_C1 PF10363.9 EGR27222.1 - 0.00011 22.3 9.0 0.0005 20.2 0.0 4.1 4 3 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 Cnd1 PF12717.7 EGR27222.1 - 0.0005 20.2 25.0 0.05 13.6 0.6 5.4 2 2 2 5 5 5 2 non-SMC mitotic condensation complex subunit 1 DCB PF16213.5 EGR27222.1 - 0.0029 17.3 1.3 0.0029 17.3 1.3 3.3 4 1 0 4 4 4 1 Dimerisation and cyclophilin-binding domain of Mon2 RICTOR_M PF14666.6 EGR27222.1 - 0.019 14.7 0.4 0.019 14.7 0.4 5.5 3 2 2 5 5 5 0 Rapamycin-insensitive companion of mTOR, middle domain TAF6_C PF07571.13 EGR27222.1 - 0.038 14.3 1.0 15 6.0 0.1 3.8 2 1 1 3 3 3 0 TAF6 C-terminal HEAT repeat domain Vac14_Fab1_bd PF12755.7 EGR27222.1 - 0.089 13.4 18.4 4.5 7.9 0.2 6.2 5 2 1 6 6 6 0 Vacuolar 14 Fab1-binding region Urb2 PF10441.9 EGR27222.1 - 0.65 9.9 3.6 1.8 8.4 0.1 3.3 3 1 0 3 3 3 0 Urb2/Npa2 family Gag_p10 PF02337.17 EGR27222.1 - 1.9 8.5 4.9 17 5.4 0.1 4.2 5 0 0 5 5 5 0 Retroviral GAG p10 protein Kinesin PF00225.23 EGR27223.1 - 3.1e-85 286.1 3.0 3.1e-85 286.1 3.0 4.5 4 2 0 5 5 5 1 Kinesin motor domain Microtub_bd PF16796.5 EGR27223.1 - 8.5e-29 100.4 0.2 8.5e-29 100.4 0.2 4.7 2 2 1 3 3 3 1 Microtubule binding MIP-T3 PF10243.9 EGR27224.1 - 5e-44 148.9 2.3 1.7e-43 147.2 0.3 2.7 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 CH-like domain Orf78 PF06024.12 EGR27224.1 - 4.1e-05 23.8 2.6 4.1e-05 23.8 2.6 3.3 2 1 0 2 2 1 1 Orf78 (ac78) LAP1C PF05609.12 EGR27224.1 - 0.00013 21.2 13.6 0.00018 20.7 13.6 1.1 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) TMEM154 PF15102.6 EGR27224.1 - 0.0017 18.3 5.9 0.0017 18.3 5.9 2.3 1 1 1 2 2 2 1 TMEM154 protein family TraG_N PF07916.11 EGR27224.1 - 0.024 13.5 0.2 0.028 13.3 0.2 1.2 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Shisa PF13908.6 EGR27224.1 - 0.056 13.7 0.1 0.056 13.7 0.1 2.4 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Chordopox_A33R PF05966.12 EGR27224.1 - 0.082 12.2 1.4 0.17 11.2 1.4 1.4 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Herpes_gE PF02480.16 EGR27224.1 - 0.092 11.5 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF4407 PF14362.6 EGR27224.1 - 0.21 10.9 13.0 0.41 10.0 13.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PBP1_TM PF14812.6 EGR27224.1 - 0.39 11.1 0.0 0.39 11.1 0.0 2.8 2 1 0 2 2 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Baculo_11_kDa PF06143.11 EGR27224.1 - 0.94 9.1 12.8 0.032 13.8 6.2 2.0 2 0 0 2 2 2 0 Baculovirus 11 kDa family GET2 PF08690.10 EGR27224.1 - 1.1 8.9 23.0 2 8.0 13.8 2.2 1 1 1 2 2 2 0 GET complex subunit GET2 7tm_1 PF00001.21 EGR27224.1 - 4.1 6.7 8.4 6.5 6.0 8.4 1.3 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Ras PF00071.22 EGR27225.1 - 2.2e-37 128.2 0.2 4e-37 127.3 0.2 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR27225.1 - 2.9e-29 101.7 0.2 7.6e-29 100.4 0.2 1.7 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR27225.1 - 1.1e-12 47.8 0.1 1.7e-12 47.2 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Hydrolase_4 PF12146.8 EGR27225.1 - 2.8e-10 39.9 0.0 4.6e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR27225.1 - 4.4e-10 39.7 0.1 3.6e-08 33.4 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.11 EGR27225.1 - 9.1e-09 35.0 0.6 1.6e-08 34.2 0.6 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) MMR_HSR1 PF01926.23 EGR27225.1 - 7.4e-07 29.2 0.0 1.8e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGR27225.1 - 0.0046 16.4 0.2 0.0081 15.5 0.2 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Lipase_3 PF01764.25 EGR27225.1 - 0.0057 16.5 0.0 0.011 15.5 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) GTP_EFTU PF00009.27 EGR27225.1 - 0.007 15.9 0.1 0.062 12.8 0.1 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 EGR27225.1 - 0.0084 15.8 0.1 0.065 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 EGR27225.1 - 0.0096 15.4 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit LIDHydrolase PF10230.9 EGR27225.1 - 0.01 15.4 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase RsgA_GTPase PF03193.16 EGR27225.1 - 0.01 15.7 0.0 0.029 14.3 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 EGR27225.1 - 0.025 14.8 0.0 0.052 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain VirJ PF06057.11 EGR27225.1 - 0.032 14.1 0.0 0.095 12.6 0.0 1.7 1 0 0 1 1 1 0 Bacterial virulence protein (VirJ) AAA_16 PF13191.6 EGR27225.1 - 0.06 13.7 0.0 0.099 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Ser_hydrolase PF06821.13 EGR27225.1 - 0.069 13.0 0.0 3.7 7.4 0.0 2.5 3 0 0 3 3 3 0 Serine hydrolase Palm_thioest PF02089.15 EGR27225.1 - 0.1 12.5 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase ABC_tran PF00005.27 EGR27225.1 - 0.13 12.8 0.0 0.29 11.6 0.0 1.6 1 0 0 1 1 1 0 ABC transporter DUF3530 PF12048.8 EGR27225.1 - 0.14 11.5 0.0 0.28 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) DEAD PF00270.29 EGR27226.1 - 3.8e-41 140.8 0.2 5.9e-41 140.1 0.2 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR27226.1 - 4.4e-32 110.7 1.8 8.1e-30 103.4 0.4 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 EGR27226.1 - 0.00072 19.6 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGR27226.1 - 0.003 16.8 0.1 0.0047 16.2 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Flavi_DEAD PF07652.14 EGR27226.1 - 0.17 11.9 0.1 0.5 10.3 0.0 1.8 1 1 1 2 2 2 0 Flavivirus DEAD domain EF-hand_1 PF00036.32 EGR27227.1 - 1.6e-24 83.6 21.1 2.1e-08 33.1 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGR27227.1 - 5.9e-23 81.1 16.5 1.2e-14 54.5 2.8 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR27227.1 - 6.7e-22 75.5 14.2 1.6e-08 33.8 0.2 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGR27227.1 - 4.9e-17 61.5 19.5 4.5e-09 36.0 1.0 4.2 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EGR27227.1 - 2.9e-13 48.7 15.6 3.8e-05 23.0 0.6 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EGR27227.1 - 5.2e-09 36.3 1.3 0.0011 19.3 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EGR27227.1 - 2.9e-07 30.8 8.1 0.0023 18.2 2.2 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGR27227.1 - 8.3e-05 22.5 12.4 0.07 13.1 3.2 3.6 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SurA_N_3 PF13624.6 EGR27227.1 - 0.0003 20.6 15.3 0.043 13.6 8.2 2.6 1 1 1 2 2 2 2 SurA N-terminal domain Caleosin PF05042.13 EGR27227.1 - 0.007 16.3 1.8 2.1 8.2 0.0 3.0 1 1 2 3 3 3 1 Caleosin related protein DUF853 PF05872.12 EGR27227.1 - 0.016 13.8 1.1 0.037 12.6 0.2 1.8 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) Herpes_UL36 PF03586.13 EGR27227.1 - 0.033 13.5 1.2 0.045 13.1 0.3 1.6 2 0 0 2 2 2 0 Herpesvirus UL36 tegument protein AEP1 PF17049.5 EGR27227.1 - 0.047 12.8 5.8 1.1 8.3 0.5 2.1 1 1 1 2 2 2 0 ATPase expression protein 1 Dockerin_1 PF00404.18 EGR27227.1 - 0.048 13.9 1.8 0.63 10.3 0.6 2.9 2 1 0 2 2 2 0 Dockerin type I domain TerB PF05099.13 EGR27227.1 - 0.07 13.1 4.9 0.068 13.1 0.8 2.5 1 1 1 2 2 2 0 Tellurite resistance protein TerB Acetyltransf_11 PF13720.6 EGR27227.1 - 0.11 13.0 0.9 0.56 10.7 0.1 2.3 2 1 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Viral_Rep PF02407.16 EGR27227.1 - 0.18 12.1 1.5 1.1 9.5 0.1 2.4 2 0 0 2 2 2 0 Putative viral replication protein TRCF PF03461.15 EGR27227.1 - 0.77 10.2 5.0 0.9 10.0 0.6 2.5 1 1 1 2 2 2 0 TRCF domain EF-hand_14 PF17959.1 EGR27227.1 - 8.2 6.9 9.6 7.1 7.0 0.4 3.2 2 1 1 3 3 2 0 EF-hand domain zf-RING_2 PF13639.6 EGR27228.1 - 1.8e-12 47.4 7.0 2.8e-12 46.8 7.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGR27228.1 - 1.6e-09 37.3 3.7 3.6e-09 36.2 3.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EGR27228.1 - 4.5e-09 36.0 5.6 8.5e-09 35.2 5.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGR27228.1 - 2.1e-07 30.7 6.6 3.3e-07 30.0 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGR27228.1 - 2.8e-07 30.7 9.3 8.1e-07 29.2 9.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGR27228.1 - 4.4e-07 29.8 2.6 8.1e-07 29.0 2.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGR27228.1 - 7.7e-05 22.6 4.6 0.00013 21.8 4.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain DUF1272 PF06906.11 EGR27228.1 - 0.00092 19.3 1.3 0.0016 18.5 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-C3HC4_3 PF13920.6 EGR27228.1 - 0.0019 18.0 3.6 0.0031 17.3 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGR27228.1 - 0.0054 16.7 5.8 0.013 15.5 5.8 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGR27228.1 - 0.02 14.7 4.9 0.037 13.8 4.9 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHD PF00628.29 EGR27228.1 - 0.15 12.0 7.7 0.3 11.0 7.7 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3H2C3 PF17122.5 EGR27228.1 - 0.3 11.1 2.3 0.78 9.8 2.3 1.7 1 1 0 1 1 1 0 Zinc-finger Prok-RING_4 PF14447.6 EGR27228.1 - 0.38 10.7 4.9 0.74 9.7 4.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.7 EGR27228.1 - 0.38 10.9 6.7 1.2 9.3 6.6 1.9 1 1 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 EGR27228.1 - 0.39 10.4 7.3 0.81 9.3 7.3 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EGR27228.1 - 1.1 9.5 9.2 38 4.6 9.9 2.7 1 1 1 2 2 2 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 EGR27228.1 - 1.2 9.4 5.1 4 7.7 5.1 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 EGR27228.1 - 1.8 8.9 8.0 4.9 7.6 7.8 1.8 1 1 1 2 2 2 0 RING-like domain 2-oxoacid_dh PF00198.23 EGR27229.1 - 3.3e-74 249.2 0.1 3.7e-74 249.1 0.1 1.0 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGR27230.1 - 8.7e-18 63.9 0.3 1.4e-17 63.3 0.3 1.3 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_D23 PF16576.5 EGR27230.1 - 0.0032 16.7 0.0 0.0032 16.7 0.0 2.2 1 1 1 2 2 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion eIF-3_zeta PF05091.12 EGR27230.1 - 0.04 12.9 14.4 0.037 13.0 14.4 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spt20 PF12090.8 EGR27230.1 - 0.043 13.4 29.1 0.049 13.2 29.1 1.2 1 0 0 1 1 1 0 Spt20 family DUF3438 PF11920.8 EGR27230.1 - 0.044 13.0 9.5 0.059 12.6 9.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) RR_TM4-6 PF06459.12 EGR27230.1 - 0.098 12.5 14.8 0.099 12.5 14.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.13 EGR27230.1 - 0.15 12.0 26.6 0.15 12.0 26.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 EGR27230.1 - 0.18 12.5 17.8 0.25 12.0 17.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DDHD PF02862.17 EGR27230.1 - 0.21 11.7 7.1 0.21 11.7 7.1 1.2 1 0 0 1 1 1 0 DDHD domain DUF5308 PF17233.2 EGR27230.1 - 0.21 11.8 7.8 0.24 11.6 7.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) DUF778 PF05608.12 EGR27230.1 - 0.22 11.9 5.2 0.24 11.7 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Neur_chan_memb PF02932.16 EGR27230.1 - 0.38 10.8 7.7 0.35 10.9 7.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region NPR3 PF03666.13 EGR27230.1 - 0.9 8.3 13.0 0.93 8.2 13.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 HlyD_3 PF13437.6 EGR27230.1 - 1.1 10.0 10.8 2.2 9.0 7.2 2.5 2 1 0 2 2 2 0 HlyD family secretion protein EOS1 PF12326.8 EGR27230.1 - 1.1 9.1 2.8 1.2 9.0 2.8 1.3 1 0 0 1 1 1 0 N-glycosylation protein Androgen_recep PF02166.16 EGR27230.1 - 2.3 7.0 23.5 2.5 6.9 23.5 1.2 1 0 0 1 1 1 0 Androgen receptor CLN3 PF02487.17 EGR27230.1 - 2.7 7.0 9.7 3.1 6.7 9.7 1.1 1 0 0 1 1 1 0 CLN3 protein CobT PF06213.12 EGR27230.1 - 6.3 6.1 22.4 8.2 5.7 22.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ndc1_Nup PF09531.10 EGR27230.1 - 6.5 5.3 11.3 6.4 5.3 11.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 EGR27230.1 - 6.6 5.4 20.1 7.2 5.3 20.1 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 EGR27230.1 - 8.9 4.5 14.3 9.6 4.3 14.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Membralin PF09746.9 EGR27230.1 - 9.2 5.2 9.1 9.7 5.1 9.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein SID-1_RNA_chan PF13965.6 EGR27230.1 - 9.8 4.4 5.6 9.7 4.5 5.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Chorein_N PF12624.7 EGR27231.1 - 7.3e-30 103.5 0.4 7.3e-30 103.5 0.4 3.7 2 2 1 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13 PF16908.5 EGR27231.1 - 1.1e-10 41.8 11.9 1.1e-10 41.8 11.9 3.3 2 2 1 3 3 3 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EGR27232.1 - 2.9e-17 63.0 7.4 8.8e-15 54.9 0.1 4.0 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal PH PF00169.29 EGR27232.1 - 0.0023 18.4 1.0 0.0023 18.4 1.0 5.3 6 0 0 6 6 6 1 PH domain ATG_C PF09333.11 EGR27232.1 - 0.051 13.9 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain GNAT_acetyltr_2 PF13718.6 EGR27233.1 - 9.9e-69 231.2 0.0 2.2e-68 230.1 0.0 1.6 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 EGR27233.1 - 1.6e-56 190.9 0.0 2.8e-55 186.9 0.0 2.4 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.11 EGR27233.1 - 3.1e-34 116.8 1.8 1.6e-33 114.5 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.6 EGR27233.1 - 4e-08 33.3 0.5 1.1e-07 31.9 0.5 1.8 1 0 0 1 1 1 1 Possible tRNA binding domain Acetyltransf_7 PF13508.7 EGR27233.1 - 0.0033 17.8 0.0 0.011 16.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain AAA_30 PF13604.6 EGR27233.1 - 0.043 13.5 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Acetyltransf_1 PF00583.25 EGR27233.1 - 0.055 13.7 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Profilin PF00235.19 EGR27234.1 - 0.0046 17.2 0.3 0.028 14.7 0.0 2.6 2 0 0 2 2 2 1 Profilin PP-binding PF00550.25 EGR27235.1 - 8.4e-09 35.7 0.0 1.1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site WD40 PF00400.32 EGR27236.1 - 2.7e-10 40.7 2.9 0.0011 19.7 0.1 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat MORN PF02493.20 EGR27236.1 - 1.3e-06 27.9 9.1 2.2e-05 24.1 1.6 4.9 5 0 0 5 5 5 2 MORN repeat ANAPC4_WD40 PF12894.7 EGR27236.1 - 1.5e-06 28.4 0.7 0.87 9.9 0.0 4.7 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Band_3_cyto PF07565.13 EGR27236.1 - 0.88 9.3 0.0 0.88 9.3 0.0 3.1 3 1 0 3 3 3 0 Band 3 cytoplasmic domain Pkinase PF00069.25 EGR27237.1 - 5.4e-49 166.9 0.1 4.4e-40 137.7 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27237.1 - 1.5e-27 96.6 0.0 1.1e-21 77.3 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 EGR27237.1 - 1.7e-05 24.2 0.0 2.3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGR27237.1 - 4.4e-05 22.6 0.0 5.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGR27237.1 - 0.0019 18.1 0.0 0.0021 18.0 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGR27237.1 - 0.0049 16.5 0.2 0.0061 16.2 0.2 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase DUF1679 PF07914.11 EGR27237.1 - 0.0084 15.0 0.0 0.01 14.7 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1679) Pox_ser-thr_kin PF05445.11 EGR27237.1 - 0.0093 15.0 0.1 0.01 14.8 0.1 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kinase-like PF14531.6 EGR27237.1 - 0.065 12.5 0.0 0.068 12.5 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 EGR27237.1 - 0.076 11.8 0.0 0.1 11.3 0.0 1.2 1 1 0 1 1 1 0 Fungal protein kinase DUF1801 PF08818.11 EGR27237.1 - 0.11 13.0 0.1 0.95 10.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DU1801) CH_2 PF06294.11 EGR27238.1 - 2.1e-34 117.5 0.2 2.1e-34 117.5 0.2 2.2 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 EGR27238.1 - 4.4e-18 64.9 0.0 1.7e-17 63.0 0.0 2.0 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 EGR27238.1 - 0.0031 17.7 0.2 0.0031 17.7 0.2 2.5 1 1 0 2 2 2 1 Calponin homology (CH) domain EF-hand_12 PF17901.1 EGR27238.1 - 0.02 15.3 2.1 0.1 13.0 0.7 2.3 2 0 0 2 2 2 0 EF-hand fold domain LRR_4 PF12799.7 EGR27239.1 - 7.1e-15 54.9 24.3 2.5e-08 34.1 3.6 6.0 4 2 4 8 8 8 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGR27239.1 - 3.7e-08 33.1 15.7 2.6e-07 30.3 5.4 4.9 1 1 1 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 EGR27239.1 - 2.6e-06 27.1 8.0 2.6e-06 27.1 8.0 3.5 3 1 0 3 3 3 1 Leucine rich repeat SF3a60_bindingd PF12108.8 EGR27239.1 - 0.24 11.3 2.8 0.61 10.0 0.7 2.8 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain Fas_alpha_ACP PF18325.1 EGR27240.1 - 0.033 14.5 0.3 0.046 14.1 0.3 1.2 1 0 0 1 1 1 0 Fatty acid synthase subunit alpha Acyl carrier domain Methyltransf_11 PF08241.12 EGR27241.1 - 6.2e-09 36.4 0.0 1.2e-08 35.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGR27241.1 - 2.8e-07 31.2 0.0 6.4e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGR27241.1 - 5.5e-07 30.2 0.0 1.1e-06 29.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGR27241.1 - 0.00063 19.6 0.0 0.00094 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGR27241.1 - 0.0037 16.6 0.0 0.0055 16.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EGR27241.1 - 0.0079 16.0 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ENTH PF01417.20 EGR27241.1 - 0.087 12.9 0.2 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 ENTH domain YL1 PF05764.13 EGR27242.1 - 0.00019 21.6 27.5 0.00019 21.6 27.5 4.5 2 2 0 3 3 3 2 YL1 nuclear protein Ribosomal_L15e PF00827.17 EGR27244.1 - 1.3e-88 295.7 6.3 1.5e-88 295.5 6.3 1.0 1 0 0 1 1 1 1 Ribosomal L15 Casc1_N PF15927.5 EGR27245.1 - 1.1e-11 44.8 18.6 1.1e-11 44.8 18.6 1.9 2 0 0 2 2 2 1 Cancer susceptibility candidate 1 N-terminus HSP90 PF00183.18 EGR27246.1 - 5.1e-30 104.9 39.8 6.8e-29 101.2 28.2 3.4 2 1 1 3 3 3 2 Hsp90 protein HATPase_c_3 PF13589.6 EGR27246.1 - 6.4e-10 39.0 0.1 1.2e-09 38.1 0.1 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGR27246.1 - 5.4e-06 26.9 0.2 1.2e-05 25.8 0.2 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Phage_connect_1 PF05135.13 EGR27246.1 - 0.066 13.7 4.3 0.097 13.2 0.2 3.3 3 0 0 3 3 3 0 Phage gp6-like head-tail connector protein MH2 PF03166.14 EGR27246.1 - 0.14 12.3 2.0 0.34 11.1 0.2 2.4 2 1 0 2 2 2 0 MH2 domain Carb_anhydrase PF00194.21 EGR27247.1 - 8.7e-38 130.3 2.4 1.1e-37 130.0 2.4 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Exonuc_VII_L PF02601.15 EGR27248.1 - 0.06 12.9 12.3 0.069 12.7 12.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit UPF0029 PF01205.19 EGR27248.1 - 0.072 13.4 0.9 0.24 11.8 0.0 2.2 2 1 0 2 2 2 0 Uncharacterized protein family UPF0029 Uso1_p115_C PF04871.13 EGR27248.1 - 8 6.9 12.5 3.2 8.2 4.6 2.1 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region RB_B PF01857.20 EGR27249.1 - 1e-21 77.4 4.0 1.5e-21 76.8 4.0 1.3 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain DUF5492 PF17596.2 EGR27249.1 - 0.0042 17.4 4.8 0.0055 17.0 4.0 1.5 1 1 0 1 1 1 1 Family of unknown function (DUF5492) Pkinase PF00069.25 EGR27251.1 - 6.2e-49 166.7 5.5 1.7e-47 162.0 5.5 2.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27251.1 - 6.9e-21 74.7 0.0 9.6e-21 74.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR27251.1 - 6.5e-07 29.5 0.0 1.1e-05 25.4 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGR27251.1 - 0.41 10.2 4.9 0.8 9.3 0.0 3.1 2 2 1 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 ERGIC_N PF13850.6 EGR27252.1 - 0.00013 22.2 0.1 0.00024 21.4 0.1 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) MORN PF02493.20 EGR27253.1 - 9.8e-49 160.4 53.1 1.1e-07 31.4 0.2 10.1 10 0 0 10 10 10 9 MORN repeat zf-RING_UBOX PF13445.6 EGR27254.1 - 5e-08 32.8 23.9 0.00046 20.2 1.1 5.1 4 0 0 4 4 4 2 RING-type zinc-finger zf-RING_5 PF14634.6 EGR27254.1 - 5.5e-08 32.6 21.7 2.9e-05 24.0 3.9 8.1 8 3 0 8 8 8 2 zinc-RING finger domain zf-RING_2 PF13639.6 EGR27254.1 - 4.6e-07 30.1 3.7 4.6e-07 30.1 3.7 7.5 6 2 1 7 7 7 2 Ring finger domain zf-rbx1 PF12678.7 EGR27254.1 - 0.00011 22.4 3.9 0.00011 22.4 3.9 5.7 5 2 0 5 5 5 2 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGR27254.1 - 0.00016 21.5 0.5 0.00016 21.5 0.5 7.7 10 1 0 10 10 10 2 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGR27254.1 - 0.00083 19.1 4.9 0.00083 19.1 4.9 3.6 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4 PF00097.25 EGR27254.1 - 0.0014 18.5 24.2 0.0028 17.5 10.9 8.4 7 2 1 8 8 8 2 Zinc finger, C3HC4 type (RING finger) WD40 PF00400.32 EGR27255.1 - 5.6e-27 93.4 15.7 9.6e-07 29.4 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR27255.1 - 2.5e-10 40.5 0.0 0.0096 16.2 0.0 4.5 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGR27255.1 - 0.00031 20.2 9.8 0.041 13.2 5.6 2.5 1 1 1 2 2 2 2 WD40-like domain Frtz PF11768.8 EGR27255.1 - 0.0045 15.4 0.3 0.091 11.1 0.4 2.6 2 1 2 4 4 4 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF5046 PF16465.5 EGR27255.1 - 0.011 15.3 0.1 0.62 9.5 0.0 2.7 1 1 2 3 3 3 0 Domain of unknown function (DUF5046) CitMHS PF03600.16 EGR27256.1 - 0.003 16.8 0.2 0.003 16.8 0.2 1.2 1 0 0 1 1 1 1 Citrate transporter HD_3 PF13023.6 EGR27256.1 - 7.7 6.4 9.6 0.28 11.1 0.2 2.4 2 1 0 2 2 2 0 HD domain tRNA_U5-meth_tr PF05958.11 EGR27257.1 - 1.9e-07 30.4 2.1 1.9e-07 30.4 2.1 2.4 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 EGR27257.1 - 2.6e-06 27.3 0.3 8.7e-06 25.6 0.3 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGR27257.1 - 5.1e-06 26.1 2.1 2e-05 24.2 2.1 2.0 1 0 0 1 1 1 1 Putative methyltransferase Cons_hypoth95 PF03602.15 EGR27257.1 - 8.1e-06 25.6 0.0 2.4e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 EGR27257.1 - 4.1e-05 23.4 0.4 8.4e-05 22.4 0.4 1.5 1 0 0 1 1 1 1 Met-10+ like-protein DOT1 PF08123.13 EGR27257.1 - 9.1e-05 22.1 0.2 9.1e-05 22.1 0.2 2.2 3 0 0 3 3 3 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 EGR27257.1 - 0.0002 22.0 0.0 0.00053 20.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGR27257.1 - 0.0003 20.8 0.3 0.0003 20.8 0.3 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 EGR27257.1 - 0.0003 20.4 2.7 0.00038 20.1 0.9 2.1 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase MTS PF05175.14 EGR27257.1 - 0.00069 19.2 0.1 0.00069 19.2 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EGR27257.1 - 0.011 15.7 0.6 0.032 14.2 0.6 1.8 1 0 0 1 1 1 0 Methyltransferase domain DUF4313 PF14190.6 EGR27257.1 - 0.011 15.6 2.7 0.29 11.1 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4313) PrmA PF06325.13 EGR27257.1 - 0.012 15.1 0.7 0.035 13.5 0.7 1.8 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 EGR27257.1 - 0.015 15.1 0.1 0.036 13.8 0.1 1.6 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_16 PF10294.9 EGR27257.1 - 0.047 13.4 0.9 0.095 12.4 0.9 1.5 1 0 0 1 1 1 0 Lysine methyltransferase GidB PF02527.15 EGR27257.1 - 0.072 12.4 2.7 0.15 11.4 0.1 2.5 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Myb_DNA-binding PF00249.31 EGR27258.1 - 2.5e-21 75.6 7.8 4.2e-10 39.6 0.2 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGR27258.1 - 4e-16 59.0 9.1 4e-12 46.2 1.5 2.9 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGR27258.1 - 0.0023 17.8 0.6 0.0023 17.8 0.6 2.0 2 0 0 2 2 2 1 Myb DNA-binding like MORN PF02493.20 EGR27259.1 - 5.9e-27 91.9 41.1 1.2e-06 28.1 1.1 6.9 7 0 0 7 7 7 6 MORN repeat PilJ_C PF18223.1 EGR27260.1 - 0.54 10.8 8.1 0.065 13.7 3.2 2.0 2 1 0 2 2 2 0 Pili PilJ C-terminal domain Pkinase PF00069.25 EGR27261.1 - 3e-48 164.5 1.0 3.9e-48 164.1 1.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27261.1 - 5.3e-29 101.3 0.3 7.6e-29 100.8 0.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR27261.1 - 9.6e-08 31.2 0.0 9.6e-08 31.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR27261.1 - 7.7e-06 25.4 0.2 1.9e-05 24.1 0.0 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EGR27261.1 - 0.0055 16.3 0.2 0.008 15.7 0.2 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 EGR27261.1 - 0.011 15.7 0.0 0.027 14.4 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kinesin PF00225.23 EGR27262.1 - 1.1e-36 126.5 3.5 1.3e-36 126.2 3.5 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR27262.1 - 2e-35 121.9 5.6 3.6e-35 121.1 5.6 1.4 1 0 0 1 1 1 1 Microtubule binding T2SSE PF00437.20 EGR27262.1 - 0.00011 21.4 0.1 0.00022 20.4 0.0 1.6 1 1 1 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 EGR27262.1 - 0.19 11.4 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EGR27262.1 - 0.45 10.5 5.3 0.34 10.9 3.4 1.9 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Myb_DNA-bind_6 PF13921.6 EGR27263.1 - 1.5e-24 86.0 8.4 5.3e-16 58.6 3.1 2.2 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGR27263.1 - 4.2e-24 84.5 6.8 1.2e-11 44.6 0.1 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGR27263.1 - 6.7e-06 25.9 2.2 0.00012 21.9 0.2 2.1 1 1 1 2 2 2 1 Myb DNA-binding like SLIDE PF09111.10 EGR27263.1 - 0.0006 19.8 0.7 0.24 11.4 0.0 2.2 1 1 1 2 2 2 2 SLIDE SANT_DAMP1_like PF16282.5 EGR27263.1 - 0.0016 18.6 2.0 0.0044 17.2 0.2 2.1 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 EGR27263.1 - 0.0077 16.3 0.3 0.32 11.1 0.3 2.1 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Spore_III_AB PF09548.10 EGR27263.1 - 0.098 12.8 0.3 0.28 11.3 0.2 1.9 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) TPH PF13868.6 EGR27264.1 - 0.00017 20.2 12.3 0.00017 20.2 12.3 2.3 2 1 0 2 2 2 1 Trichohyalin-plectin-homology domain TPH PF13868.6 EGR27265.1 - 0.022 13.3 30.8 0.023 13.2 30.8 1.0 1 0 0 1 1 1 0 Trichohyalin-plectin-homology domain Piezo_RRas_bdg PF12166.8 EGR27266.1 - 3.4e-94 316.5 11.4 3.4e-94 316.5 11.4 4.5 4 2 0 4 4 4 1 Piezo non-specific cation channel, R-Ras-binding domain DUF2157 PF09925.9 EGR27266.1 - 0.0031 17.3 3.0 0.32 10.8 0.0 3.3 3 0 0 3 3 3 2 Predicted membrane protein (DUF2157) Fer4_8 PF13183.6 EGR27266.1 - 6.7 7.2 6.6 0.89 10.0 1.5 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain PAP_central PF04928.17 EGR27268.1 - 2e-66 223.5 1.2 2.7e-66 223.1 1.2 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EGR27268.1 - 8.3e-08 32.0 7.0 1.3e-07 31.4 0.3 2.7 2 1 1 3 3 3 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EGR27268.1 - 1.3e-05 25.4 0.5 7.2e-05 23.0 0.0 2.5 1 1 1 2 2 2 1 Nucleotidyltransferase domain PRD PF00874.20 EGR27268.1 - 0.0039 17.4 3.1 0.0039 17.4 3.1 4.3 4 0 0 4 4 4 1 PRD domain Nrap_D2 PF17403.2 EGR27268.1 - 0.014 15.1 0.0 0.05 13.4 0.0 1.9 1 1 0 1 1 1 0 Nrap protein PAP/OAS-like domain YtzH PF14165.6 EGR27268.1 - 0.029 14.8 2.0 0.11 12.9 2.0 2.0 1 0 0 1 1 1 0 YtzH-like protein DUF4269 PF14091.6 EGR27268.1 - 0.05 13.8 1.5 0.13 12.5 0.2 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4269) Polbeta PF18765.1 EGR27268.1 - 0.067 13.3 5.6 0.17 12.0 0.4 3.4 2 1 1 3 3 3 0 Polymerase beta, Nucleotidyltransferase Pkinase PF00069.25 EGR27269.1 - 1.3e-46 159.1 7.6 2.2e-46 158.3 7.6 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27269.1 - 1.2e-28 100.2 3.2 1.6e-28 99.7 3.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR27269.1 - 3.1e-08 32.8 0.0 4.4e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR27269.1 - 9.2e-08 31.7 0.5 1.8e-07 30.7 0.5 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGR27269.1 - 1.4e-05 24.6 0.3 2.3e-05 23.8 0.3 1.5 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 EGR27269.1 - 9.2e-05 22.1 6.1 9.2e-05 22.1 6.1 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EGR27269.1 - 0.0033 17.4 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Peptidase_C39 PF03412.15 EGR27269.1 - 0.041 13.7 0.5 0.041 13.7 0.5 2.3 1 1 1 2 2 2 0 Peptidase C39 family LT-IIB PF06453.11 EGR27269.1 - 0.12 12.3 0.5 0.34 10.8 0.3 1.8 1 1 1 2 2 2 0 Type II heat-labile enterotoxin , B subunit (LT-IIB) Metallophos PF00149.28 EGR27270.1 - 2.1e-34 119.8 0.1 3.1e-34 119.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGR27270.1 - 0.002 18.6 0.3 0.0048 17.3 0.3 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF848 PF05852.11 EGR27271.1 - 0.00031 20.9 2.0 0.00031 20.9 2.0 2.9 3 0 0 3 3 3 1 Gammaherpesvirus protein of unknown function (DUF848) Anti-adapt_IraP PF10796.9 EGR27271.1 - 2.3 8.9 9.2 0.59 10.7 0.3 3.4 3 0 0 3 3 3 0 Sigma-S stabilisation anti-adaptor protein COG6 PF06419.11 EGR27271.1 - 2.9 6.0 54.4 2.9e+02 -0.6 54.3 2.4 1 1 0 1 1 1 0 Conserved oligomeric complex COG6 Syntaxin PF00804.25 EGR27272.1 - 7.5e-20 71.5 8.0 7.5e-20 71.5 8.0 1.8 2 0 0 2 2 2 1 Syntaxin SNARE PF05739.19 EGR27272.1 - 1.7e-14 53.5 2.2 1.7e-14 53.5 2.2 1.9 2 0 0 2 2 2 1 SNARE domain FliJ PF02050.16 EGR27272.1 - 0.00028 21.1 1.2 0.00028 21.1 1.2 2.2 2 0 0 2 2 2 1 Flagellar FliJ protein SKA1 PF07160.12 EGR27272.1 - 0.01 15.7 5.8 0.01 15.7 5.8 2.5 1 1 0 2 2 2 0 Spindle and kinetochore-associated protein 1 MCPsignal PF00015.21 EGR27272.1 - 0.029 14.2 4.3 0.04 13.7 0.5 2.4 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Alanine_zipper PF11839.8 EGR27272.1 - 0.14 12.5 2.0 5.2 7.5 0.2 2.6 2 0 0 2 2 2 0 Alanine-zipper, major outer membrane lipoprotein Alpha-E PF04168.12 EGR27272.1 - 0.31 10.8 2.5 1.7 8.4 2.5 2.0 1 1 0 1 1 1 0 A predicted alpha-helical domain with a conserved ER motif. Nucleoporin_FG2 PF15967.5 EGR27272.1 - 2.1 6.8 7.1 2.6 6.5 7.1 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region FlaC_arch PF05377.11 EGR27272.1 - 4.1 7.9 10.9 10 6.6 0.5 3.7 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) CENP-T_C PF15511.6 EGR27273.1 - 1e-09 38.5 0.2 1.2e-09 38.2 0.2 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGR27273.1 - 0.00012 22.3 0.3 0.00016 22.0 0.3 1.4 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 EGR27273.1 - 0.00013 22.0 0.2 0.0002 21.5 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.24 EGR27273.1 - 0.00018 21.9 0.6 0.00028 21.2 0.7 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGR27273.1 - 0.00026 21.2 0.1 0.00041 20.6 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EGR27273.1 - 0.0014 18.6 0.1 0.0026 17.7 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 EGR27273.1 - 0.0062 16.6 0.0 0.0068 16.5 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Ribosomal_L27A PF00828.19 EGR27273.1 - 0.03 15.0 3.2 0.039 14.6 3.2 1.3 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF364 PF04016.12 EGR27273.1 - 0.067 12.8 0.0 0.091 12.3 0.0 1.3 1 1 0 1 1 1 0 Putative heavy-metal chelation TAF4 PF05236.14 EGR27273.1 - 0.078 12.7 0.1 0.089 12.5 0.1 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family AAA_18 PF13238.6 EGR27274.1 - 0.00023 21.7 1.5 0.00049 20.6 0.1 2.3 1 1 2 3 3 3 1 AAA domain AAA PF00004.29 EGR27274.1 - 0.0012 19.2 0.4 0.35 11.3 0.0 2.8 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGR27274.1 - 0.0052 17.2 0.0 0.026 14.9 0.0 2.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 EGR27274.1 - 0.0078 16.4 0.0 0.018 15.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2610 PF11020.8 EGR27274.1 - 0.0082 16.0 0.1 3.9 7.4 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF2610) MMR_HSR1 PF01926.23 EGR27274.1 - 0.012 15.7 1.1 0.048 13.7 0.1 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_28 PF13521.6 EGR27274.1 - 0.025 14.8 0.0 0.053 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGR27274.1 - 0.058 13.7 0.1 0.54 10.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 EGR27274.1 - 0.094 12.8 0.0 0.094 12.8 0.0 3.4 3 1 1 4 4 4 0 AAA domain RNA_helicase PF00910.22 EGR27274.1 - 0.097 13.1 0.1 0.097 13.1 0.1 2.8 3 2 1 4 4 4 0 RNA helicase Bac_DNA_binding PF00216.21 EGR27274.1 - 0.15 12.3 2.5 0.4 10.9 0.1 2.6 2 0 0 2 2 2 0 Bacterial DNA-binding protein RsgA_GTPase PF03193.16 EGR27274.1 - 0.23 11.4 3.6 0.3 11.0 0.9 2.5 2 1 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EGR27274.1 - 0.27 10.9 0.1 0.27 10.9 0.1 2.7 3 1 1 4 4 4 0 AAA domain AAA_17 PF13207.6 EGR27274.1 - 0.37 11.2 2.7 0.67 10.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain DUF2862 PF11061.8 EGR27274.1 - 1.2 9.0 4.9 1.5 8.8 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2862) ABC_tran PF00005.27 EGR27275.1 - 2.3e-29 102.7 1.8 6.2e-29 101.3 0.0 2.5 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EGR27275.1 - 3.7e-11 43.4 5.9 7.9e-07 29.2 0.0 3.9 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA PF00004.29 EGR27275.1 - 0.051 14.0 0.7 1.1 9.6 0.7 2.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4162 PF13732.6 EGR27275.1 - 0.33 11.7 4.0 4.5 8.1 0.6 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4162) Peptidase_M8 PF01457.16 EGR27277.1 - 2.3e-40 138.8 7.2 1e-36 126.8 0.0 3.2 2 1 1 3 3 3 2 Leishmanolysin VSP PF03302.13 EGR27277.1 - 7.5e-12 44.8 172.4 0.00046 19.1 32.1 5.4 1 1 4 5 5 5 5 Giardia variant-specific surface protein EGF_Tenascin PF18720.1 EGR27277.1 - 0.00024 21.1 6.2 0.00024 21.1 6.2 5.9 6 0 0 6 6 6 1 Tenascin EGF domain SMC_N PF02463.19 EGR27278.1 - 1.4e-06 27.9 6.8 2.2e-06 27.3 6.8 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGR27278.1 - 1.9e-05 24.6 0.0 3.5e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EGR27278.1 - 2.2e-05 24.6 0.0 9.5e-05 22.6 0.0 1.9 1 1 1 2 2 2 1 Putative exonuclease SbcCD, C subunit MecA_N PF05223.11 EGR27278.1 - 0.0026 18.0 0.7 0.0026 18.0 0.7 2.0 1 1 1 2 2 2 1 NTF2-like N-terminal transpeptidase domain ABC_tran PF00005.27 EGR27278.1 - 0.099 13.2 0.5 0.25 11.9 0.5 1.9 1 1 0 1 1 1 0 ABC transporter AAA_23 PF13476.6 EGR27279.1 - 3.3e-20 73.4 7.1 4.2e-20 73.1 7.1 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EGR27279.1 - 1.1e-07 32.0 9.1 1.6e-07 31.4 9.1 1.2 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EGR27279.1 - 2.2e-06 27.3 0.8 3.4e-06 26.7 0.8 1.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGR27279.1 - 8.3e-06 25.8 1.0 1.1e-05 25.5 1.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGR27279.1 - 2e-05 24.3 1.3 6.1e-05 22.7 0.1 2.1 1 1 1 2 2 2 1 P-loop containing region of AAA domain AAA_13 PF13166.6 EGR27279.1 - 0.0011 17.7 0.4 0.0011 17.7 0.4 1.6 1 1 1 2 2 2 1 AAA domain ABC_tran PF00005.27 EGR27279.1 - 0.0031 18.0 3.6 0.012 16.1 3.6 2.0 1 1 0 1 1 1 1 ABC transporter AAA_27 PF13514.6 EGR27279.1 - 0.01 15.4 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGR27279.1 - 0.046 14.3 0.4 0.077 13.5 0.4 1.5 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGR27279.1 - 0.047 13.9 0.4 0.074 13.3 0.4 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGR27279.1 - 0.12 12.6 0.4 0.27 11.5 0.2 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGR27279.1 - 0.19 12.1 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain WD40 PF00400.32 EGR27280.1 - 3.9e-19 68.6 5.6 0.012 16.5 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR27280.1 - 1.2e-11 44.8 0.1 0.00046 20.4 0.0 5.0 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGR27280.1 - 6.2e-09 35.6 4.9 7.2e-06 25.5 0.5 2.4 1 1 1 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 EGR27280.1 - 0.00031 19.8 3.4 5.4 5.9 0.0 4.4 1 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EGR27280.1 - 0.0014 17.4 3.7 0.58 8.8 0.7 2.8 1 1 1 2 2 2 2 Nup133 N terminal like BRCA2 PF00634.18 EGR27280.1 - 0.054 13.2 0.8 0.15 11.8 0.8 1.8 1 0 0 1 1 1 0 BRCA2 repeat PhoLip_ATPase_C PF16212.5 EGR27281.1 - 2.3e-50 171.7 27.7 2.3e-50 171.7 27.7 3.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal E1-E2_ATPase PF00122.20 EGR27281.1 - 6.8e-14 51.8 0.0 6.8e-14 51.8 0.0 2.7 3 0 0 3 3 3 1 E1-E2 ATPase PhoLip_ATPase_N PF16209.5 EGR27281.1 - 8.9e-14 50.9 6.3 4.8e-13 48.6 6.3 2.4 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGR27281.1 - 4.5e-11 42.7 1.9 4.8e-11 42.6 0.1 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGR27281.1 - 5.1e-06 26.9 0.0 0.0059 16.9 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGR27281.1 - 2.6 7.7 18.3 0.17 11.6 9.8 3.0 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Polyoma_coat2 PF00761.20 EGR27282.1 - 0.41 10.3 1.5 0.45 10.2 0.7 1.4 2 0 0 2 2 2 0 Polyomavirus coat protein DUF3824 PF12868.7 EGR27282.1 - 0.7 10.5 7.1 0.9 10.2 7.1 1.1 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) DUF4950 PF16308.5 EGR27283.1 - 0.14 12.1 0.1 0.19 11.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4950) Hydrolase_4 PF12146.8 EGR27284.1 - 1.4e-10 40.9 0.0 1.6e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR27284.1 - 8.4e-09 35.4 0.0 1.2e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EGR27284.1 - 0.00041 20.0 0.0 0.0005 19.8 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) DUF1749 PF08538.10 EGR27284.1 - 0.003 16.7 0.0 0.004 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) WH2 PF02205.20 EGR27285.1 - 0.00063 19.5 0.2 0.0013 18.5 0.2 1.5 1 0 0 1 1 1 1 WH2 motif DUF5446 PF17522.2 EGR27286.1 - 0.024 14.8 0.3 0.13 12.5 0.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5446) U62_UL91 PF17442.2 EGR27286.1 - 0.58 10.2 4.3 3 7.9 0.5 2.5 3 0 0 3 3 3 0 Functional domain of U62 and UL91 proteins Pyr_redox_2 PF07992.14 EGR27288.1 - 4e-34 118.2 0.0 6.1e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGR27288.1 - 9.5e-26 90.2 0.0 2.1e-25 89.1 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGR27288.1 - 1.5e-15 57.5 0.3 2.6e-12 47.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGR27288.1 - 2.2e-07 30.5 0.1 0.024 13.9 0.0 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGR27288.1 - 2.3e-05 23.7 0.8 4.9e-05 22.6 0.8 1.5 1 0 0 1 1 1 1 FAD binding domain K_oxygenase PF13434.6 EGR27288.1 - 0.0002 20.7 0.2 0.11 11.6 0.0 2.8 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EGR27288.1 - 0.0004 19.2 0.1 0.013 14.2 0.1 2.4 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 EGR27288.1 - 0.00054 19.3 0.0 0.00099 18.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 EGR27288.1 - 0.0011 19.2 2.2 0.009 16.2 0.1 2.5 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EGR27288.1 - 0.0012 18.0 3.0 0.022 13.8 0.2 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A DAO PF01266.24 EGR27288.1 - 0.0026 17.4 1.1 0.0068 16.0 0.1 2.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 EGR27288.1 - 0.0047 16.3 0.0 0.04 13.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Peptidase_Mx PF15887.5 EGR27288.1 - 0.0065 15.9 0.1 0.012 15.0 0.1 1.4 1 0 0 1 1 1 1 Putative zinc-binding metallo-peptidase AlaDh_PNT_C PF01262.21 EGR27288.1 - 0.057 12.7 0.0 9.2 5.5 0.0 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EGR27288.1 - 0.11 11.6 0.1 0.16 10.9 0.1 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein YabA PF06156.13 EGR27289.1 - 0.054 14.1 4.2 0.056 14.1 4.2 1.0 1 0 0 1 1 1 0 Initiation control protein YabA EF-hand_7 PF13499.6 EGR27290.1 - 5.1e-19 68.5 29.9 1.1e-06 28.9 0.9 6.9 6 0 0 6 6 6 3 EF-hand domain pair EF-hand_1 PF00036.32 EGR27290.1 - 1.1e-18 65.3 17.1 0.00023 20.5 0.0 6.5 6 0 0 6 6 6 5 EF hand EF-hand_6 PF13405.6 EGR27290.1 - 4e-18 63.7 15.0 0.00046 19.9 0.1 6.7 5 0 0 5 5 5 5 EF-hand domain EF-hand_8 PF13833.6 EGR27290.1 - 9.8e-18 63.8 6.9 1.3e-06 28.2 0.1 4.4 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGR27290.1 - 2.2e-10 39.6 11.5 0.0015 17.9 0.1 5.5 5 0 0 5 5 5 3 EF hand FAA_hydro_N_2 PF18288.1 EGR27290.1 - 2.7 8.5 7.8 22 5.6 0.5 5.1 3 1 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 DUF98 PF01947.16 EGR27291.1 - 0.0054 16.7 0.1 0.0054 16.7 0.1 1.5 2 0 0 2 2 2 1 p-hydroxybenzoic acid synthase Jnk-SapK_ap_N PF09744.9 EGR27291.1 - 0.0096 16.2 12.7 0.011 15.9 12.7 1.2 1 0 0 1 1 1 1 JNK_SAPK-associated protein-1 Nsp1_C PF05064.13 EGR27291.1 - 0.025 14.4 7.8 0.019 14.8 6.3 1.6 1 1 0 1 1 1 0 Nsp1-like C-terminal region mRNA_cap_C PF03919.15 EGR27291.1 - 0.11 13.1 4.4 0.14 12.8 4.4 1.3 1 1 0 1 1 1 0 mRNA capping enzyme, C-terminal domain Noelin-1 PF12308.8 EGR27291.1 - 0.23 11.5 5.5 1.5 8.8 0.3 2.3 1 1 1 2 2 2 0 Neurogenesis glycoprotein DUF1664 PF07889.12 EGR27291.1 - 0.27 11.3 7.2 0.14 12.2 4.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) TMF_DNA_bd PF12329.8 EGR27291.1 - 0.28 11.2 14.5 0.083 12.9 11.0 1.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Spc29 PF17082.5 EGR27291.1 - 0.48 10.2 13.2 2.6 7.8 13.2 1.8 1 1 0 1 1 1 0 Spindle Pole Component 29 Histidinol_dh PF00815.20 EGR27291.1 - 0.5 9.3 4.6 0.57 9.1 4.6 1.0 1 0 0 1 1 1 0 Histidinol dehydrogenase Lectin_N PF03954.14 EGR27291.1 - 1.1 9.0 6.5 0.32 10.7 2.9 1.8 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain DUF3552 PF12072.8 EGR27291.1 - 1.1 8.6 16.2 1.3 8.5 16.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) E2F_CC-MB PF16421.5 EGR27291.1 - 1.3 9.4 10.0 0.19 12.1 3.5 2.3 1 1 1 2 2 2 0 E2F transcription factor CC-MB domain DUF4140 PF13600.6 EGR27291.1 - 1.5 9.3 8.1 2.5 8.6 2.4 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Exonuc_VII_L PF02601.15 EGR27291.1 - 3.6 7.1 12.2 3.8 7.0 12.2 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Macoilin PF09726.9 EGR27291.1 - 6.8 5.1 14.6 7.3 5.0 14.6 1.0 1 0 0 1 1 1 0 Macoilin family XhlA PF10779.9 EGR27291.1 - 7.1 6.9 8.2 11 6.3 0.3 2.5 1 1 1 2 2 2 0 Haemolysin XhlA cNMP_binding PF00027.29 EGR27292.1 - 1.9e-16 59.9 0.0 3.2e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGR27292.1 - 7.6e-05 22.6 3.5 0.00014 21.8 3.5 1.4 1 0 0 1 1 1 1 Ion channel APG5 PF04106.12 EGR27292.1 - 0.37 10.3 3.2 0.52 9.9 0.2 2.1 2 0 0 2 2 2 0 Autophagy protein Apg5 Pkinase PF00069.25 EGR27293.1 - 5.2e-36 124.4 7.4 9.8e-25 87.4 1.3 5.5 6 2 0 6 6 6 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27293.1 - 1.1e-19 70.7 7.6 1.1e-19 70.7 7.6 4.8 4 1 0 4 4 4 1 Protein tyrosine kinase Kinesin PF00225.23 EGR27294.1 - 2.5e-99 332.4 10.3 7.6e-54 182.9 5.0 2.9 2 1 1 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 EGR27294.1 - 2.3e-27 95.8 4.6 2.3e-27 95.8 4.6 2.5 3 1 0 3 3 3 1 Microtubule binding DUF1996 PF09362.10 EGR27294.1 - 0.091 12.8 1.2 0.19 11.7 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1996) Kinesin_assoc PF16183.5 EGR27294.1 - 9 6.4 20.3 6.1 7.0 15.8 2.8 2 1 0 2 2 2 0 Kinesin-associated Ion_trans PF00520.31 EGR27295.1 - 1e-16 60.9 18.8 1e-16 60.9 18.8 2.1 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 EGR27295.1 - 4.8e-11 42.5 11.7 4.8e-11 42.5 11.7 2.5 2 1 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 EGR27295.1 - 2.8e-07 30.5 0.1 4.7e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF3675 PF12428.8 EGR27295.1 - 0.0025 18.4 1.2 0.0025 18.4 1.2 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3675) zinc_ribbon_6 PF14599.6 EGR27295.1 - 0.33 11.0 3.5 0.17 11.9 0.7 2.0 2 0 0 2 2 2 0 Zinc-ribbon Peptidase_M8 PF01457.16 EGR27296.1 - 4.4e-38 131.3 10.1 4.6e-35 121.3 0.4 3.8 3 1 1 4 4 4 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR27296.1 - 1.8e-06 27.8 9.5 1.8e-06 27.8 9.5 5.7 6 0 0 6 6 6 1 Tenascin EGF domain VSP PF03302.13 EGR27296.1 - 0.11 11.3 121.6 0.066 12.1 23.6 4.4 1 1 3 4 4 4 0 Giardia variant-specific surface protein Peptidase_M8 PF01457.16 EGR27297.1 - 7.9e-43 146.9 0.0 7.9e-43 146.9 0.0 2.5 2 0 0 2 2 2 1 Leishmanolysin Collagen PF01391.18 EGR27297.1 - 5.6e-12 45.2 40.8 0.00031 20.4 8.2 3.8 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) EGF_Tenascin PF18720.1 EGR27297.1 - 8.1e-07 29.0 11.6 8.1e-07 29.0 11.6 4.2 3 0 0 3 3 3 1 Tenascin EGF domain GF_recep_IV PF14843.6 EGR27297.1 - 2.7e-05 24.0 28.9 2.7e-05 24.0 28.9 5.7 2 1 3 5 5 5 2 Growth factor receptor domain IV Furin-like_2 PF15913.5 EGR27297.1 - 0.0012 18.9 14.1 0.0012 18.9 14.1 7.7 2 2 5 7 7 7 2 Furin-like repeat, cysteine-rich Peptidase_M8 PF01457.16 EGR27298.1 - 8.6e-38 130.3 13.5 2.9e-36 125.3 0.7 3.8 2 2 2 4 4 4 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR27298.1 - 7e-08 32.3 9.7 7e-08 32.3 9.7 4.8 3 0 0 3 3 3 1 Tenascin EGF domain VSP PF03302.13 EGR27298.1 - 0.0084 15.0 163.6 0.6 8.9 26.6 6.5 1 1 5 6 6 6 5 Giardia variant-specific surface protein VSP PF03302.13 EGR27299.1 - 3.9e-06 26.0 93.5 0.11 11.3 22.9 4.9 1 1 3 4 4 4 4 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EGR27299.1 - 2 8.6 93.1 1.6 8.9 10.5 5.9 1 1 3 5 5 5 0 Furin-like repeat, cysteine-rich Pkinase PF00069.25 EGR27300.1 - 5.5e-79 265.3 1.2 6.6e-79 265.0 1.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27300.1 - 5e-48 163.6 0.1 6.5e-48 163.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27300.1 - 7e-09 35.4 0.0 5.5e-08 32.5 0.0 1.9 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGR27300.1 - 0.00016 21.1 0.2 0.00034 20.0 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGR27300.1 - 0.00026 20.1 2.0 0.0005 19.1 2.0 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGR27300.1 - 0.024 14.5 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EGR27300.1 - 0.049 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EGR27300.1 - 0.059 13.0 0.3 0.059 13.0 0.3 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.22 EGR27300.1 - 0.074 12.6 0.9 0.13 11.9 0.9 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 EGR27301.1 - 9.4e-67 225.1 0.3 2.3e-66 223.9 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27301.1 - 4e-37 127.9 0.0 8e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27301.1 - 4.1e-05 23.0 1.9 0.0013 18.1 0.0 2.9 2 1 1 3 3 3 1 Kinase-like TFIIA PF03153.13 EGR27302.1 - 0.0003 20.9 37.3 0.00032 20.8 37.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit MAP7 PF05672.11 EGR27302.1 - 0.12 12.0 51.1 0.26 11.0 51.1 1.6 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family THRAP3_BCLAF1 PF15440.6 EGR27302.1 - 0.27 10.2 33.2 0.35 9.9 33.2 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family Dapper PF15268.6 EGR27302.1 - 0.47 9.2 23.9 0.5 9.1 23.9 1.2 1 0 0 1 1 1 0 Dapper Asp-B-Hydro_N PF05279.11 EGR27302.1 - 1.1 9.2 41.3 1.7 8.6 41.3 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region SLC12 PF03522.15 EGR27302.1 - 2.7 6.9 22.2 3.9 6.4 22.2 1.3 1 0 0 1 1 1 0 Solute carrier family 12 PA26 PF04636.13 EGR27302.1 - 3 6.7 17.3 5 5.9 17.3 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Membralin PF09746.9 EGR27302.1 - 8.5 5.3 17.0 13 4.7 17.0 1.3 1 0 0 1 1 1 0 Tumour-associated protein Ribonuclease_T2 PF00445.18 EGR27303.1 - 1.6e-38 132.8 5.1 2.1e-38 132.4 5.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Mu-conotoxin PF05374.12 EGR27303.1 - 0.1 12.6 4.3 0.21 11.7 0.7 2.3 2 0 0 2 2 2 0 Mu-Conotoxin Gcd10p PF04189.13 EGR27304.1 - 1.5e-07 30.8 13.5 2.6e-06 26.8 4.9 2.6 2 1 1 3 3 3 2 Gcd10p family Peptidase_S30 PF01577.16 EGR27304.1 - 0.073 12.7 1.1 0.23 11.1 1.4 1.6 2 0 0 2 2 2 0 Potyvirus P1 protease RPAP1_N PF08621.10 EGR27304.1 - 2.2 8.1 5.8 1.3 8.9 2.2 2.5 2 1 0 2 2 2 0 RPAP1-like, N-terminal cNMP_binding PF00027.29 EGR27305.1 - 2.6e-16 59.4 0.0 4.8e-16 58.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 EGR27305.1 - 3.2e-16 59.3 30.8 5.3e-16 58.6 30.8 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGR27305.1 - 1.1e-12 47.7 4.8 1.1e-12 47.7 4.8 2.3 2 1 0 2 2 2 1 Ion channel zf-CCHC PF00098.23 EGR27305.1 - 7.7e-05 22.6 2.1 0.00016 21.6 2.1 1.6 1 0 0 1 1 1 1 Zinc knuckle DctQ PF04290.12 EGR27305.1 - 0.012 15.5 0.1 0.012 15.5 0.1 2.3 2 0 0 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component zf-CCHC_4 PF14392.6 EGR27305.1 - 0.015 15.0 0.1 0.083 12.6 0.1 2.2 2 0 0 2 2 2 0 Zinc knuckle Thioredoxin PF00085.20 EGR27306.1 - 4.2e-14 52.4 0.2 6.4e-08 32.5 0.0 3.3 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 EGR27306.1 - 7.9e-10 38.9 1.5 0.0031 17.4 0.1 3.6 2 1 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGR27306.1 - 0.0015 18.8 0.2 8.8 6.7 0.0 3.5 3 0 0 3 3 3 2 Thioredoxin-like TraF PF13728.6 EGR27306.1 - 0.0016 18.3 0.0 0.051 13.4 0.0 2.8 3 0 0 3 3 3 1 F plasmid transfer operon protein HyaE PF07449.11 EGR27306.1 - 0.018 15.0 0.0 0.22 11.5 0.0 2.7 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE RRM_occluded PF16842.5 EGR27306.1 - 0.023 14.5 0.0 0.047 13.5 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Thioredoxin_2 PF13098.6 EGR27306.1 - 0.058 13.9 0.1 0.52 10.8 0.0 2.5 2 1 0 3 3 3 0 Thioredoxin-like domain MORN PF02493.20 EGR27307.1 - 2.5e-48 159.2 63.9 1.3e-07 31.1 0.5 10.1 10 0 0 10 10 10 9 MORN repeat Tudor_2 PF18104.1 EGR27307.1 - 0.19 11.5 5.6 6.6 6.5 0.1 4.1 3 0 0 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain Rio2_N PF09202.11 EGR27307.1 - 0.73 10.1 4.3 0.38 11.0 0.7 2.5 2 0 0 2 2 2 0 Rio2, N-terminal RabGAP-TBC PF00566.18 EGR27308.1 - 1.9e-28 99.6 8.7 2.3e-28 99.4 8.7 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF5363 PF17320.2 EGR27308.1 - 0.091 12.6 0.0 0.37 10.7 0.0 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5363) PI3_PI4_kinase PF00454.27 EGR27309.1 - 2.9e-48 164.8 0.4 4.5e-31 108.6 0.1 2.3 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 EGR27309.1 - 1.1e-05 24.9 0.0 1.9e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) DUF4467 PF14729.6 EGR27309.1 - 0.041 14.2 2.4 0.061 13.7 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function with cystatin-like fold (DUF4467) SUKH-3 PF14433.6 EGR27309.1 - 0.067 13.7 0.1 1.5 9.3 0.0 2.3 2 0 0 2 2 2 0 SUKH-3 immunity protein RrnaAD PF00398.20 EGR27310.1 - 3.8e-61 206.5 0.2 5.9e-61 205.8 0.2 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EGR27310.1 - 2.3e-09 37.8 0.0 4.9e-09 36.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGR27310.1 - 2.3e-06 28.2 0.0 5.3e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGR27310.1 - 2.6e-06 28.1 4.5 5.1e-06 27.1 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGR27310.1 - 5.1e-05 23.2 0.3 0.00013 21.8 0.3 2.0 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGR27310.1 - 0.0036 17.1 0.0 0.0068 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EGR27310.1 - 0.0089 15.6 0.0 0.019 14.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 EGR27310.1 - 0.0093 16.0 2.8 0.2 11.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGR27310.1 - 0.012 15.0 0.0 0.025 13.9 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 EGR27310.1 - 0.036 14.0 0.0 0.077 12.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AAA_11 PF13086.6 EGR27310.1 - 0.077 12.8 5.4 0.14 12.0 5.4 1.4 1 0 0 1 1 1 0 AAA domain NodS PF05401.11 EGR27310.1 - 0.099 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) DUF775 PF05603.12 EGR27310.1 - 0.24 10.9 5.5 0.4 10.2 5.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) TRAP_alpha PF03896.16 EGR27310.1 - 0.38 9.9 9.7 0.57 9.3 9.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PI3K_1B_p101 PF10486.9 EGR27310.1 - 0.44 8.3 8.2 0.57 7.9 8.2 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit FAM176 PF14851.6 EGR27310.1 - 1.8 8.2 7.2 3.3 7.4 7.2 1.3 1 0 0 1 1 1 0 FAM176 family PKD_channel PF08016.12 EGR27311.1 - 4.9e-07 28.8 15.3 4.9e-07 28.8 15.3 2.1 2 0 0 2 2 2 1 Polycystin cation channel PBP1_TM PF14812.6 EGR27311.1 - 0.14 12.5 8.9 2.7 8.4 0.3 2.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3134 PF11332.8 EGR27311.1 - 0.47 10.8 5.9 1.3 9.3 5.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3134) Ras PF00071.22 EGR27312.1 - 2.8e-58 196.1 0.8 4.9e-58 195.3 0.8 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR27312.1 - 5.7e-34 116.9 0.4 5.7e-34 116.9 0.4 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR27312.1 - 2.7e-11 43.2 0.5 3.7e-11 42.8 0.5 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR27312.1 - 9.5e-08 32.1 0.1 1.7e-07 31.3 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGR27312.1 - 8.8e-05 22.1 0.3 0.00051 19.6 0.3 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGR27312.1 - 0.00036 20.0 0.3 0.00082 18.9 0.3 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 EGR27312.1 - 0.0021 17.5 0.1 0.011 15.2 0.1 2.1 1 1 0 1 1 1 1 Bacterial TniB protein Gtr1_RagA PF04670.12 EGR27312.1 - 0.016 14.5 0.3 0.016 14.5 0.3 1.6 1 1 0 2 2 2 0 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGR27312.1 - 0.033 14.1 1.6 1 9.2 0.0 2.5 3 0 0 3 3 3 0 RsgA GTPase Ras PF00071.22 EGR27313.1 - 2.3e-55 186.6 0.3 2.9e-55 186.3 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR27313.1 - 6.6e-37 126.4 0.0 1.1e-36 125.6 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR27313.1 - 1.8e-17 63.3 0.1 2.2e-17 63.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGR27313.1 - 8.1e-08 32.0 0.0 5.9e-06 26.0 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGR27313.1 - 1.7e-06 28.1 0.0 2.5e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGR27313.1 - 5.1e-05 22.7 0.1 6.7e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGR27313.1 - 0.0011 18.5 0.2 0.0044 16.5 0.0 1.8 1 1 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EGR27313.1 - 0.0013 18.3 0.1 0.0025 17.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EGR27313.1 - 0.0058 16.6 0.1 0.27 11.1 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1_Xtn PF16897.5 EGR27313.1 - 0.006 16.6 0.2 0.0096 15.9 0.2 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TniB PF05621.11 EGR27313.1 - 0.013 14.9 0.0 0.035 13.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein EMC3_TMCO1 PF01956.16 EGR27313.1 - 0.04 13.7 0.9 0.064 13.0 0.9 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like FeoB_N PF02421.18 EGR27313.1 - 0.049 13.2 0.0 0.67 9.5 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B MFS_1 PF07690.16 EGR27314.1 - 0.00021 20.3 0.0 0.00021 20.3 0.0 2.6 3 0 0 3 3 3 2 Major Facilitator Superfamily IL17_R_N PF15037.6 EGR27314.1 - 0.032 13.2 0.1 0.049 12.6 0.1 1.2 1 0 0 1 1 1 0 Interleukin-17 receptor extracellular region DUF983 PF06170.12 EGR27314.1 - 0.061 13.7 0.6 0.061 13.7 0.6 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF983) Cation_efflux PF01545.21 EGR27315.1 - 4.3e-51 173.5 7.0 5.2e-51 173.2 7.0 1.1 1 0 0 1 1 1 1 Cation efflux family Nmad2 PF18753.1 EGR27315.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Nucleotide modification associated domain 2 DUF983 PF06170.12 EGR27315.1 - 0.7 10.3 5.6 0.63 10.5 0.5 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF983) DUF2663 PF10864.8 EGR27315.1 - 4.2 7.8 6.3 2.1 8.8 0.2 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF2663) TPR_1 PF00515.28 EGR27316.1 - 2e-06 27.4 0.2 0.011 15.5 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGR27316.1 - 0.00011 22.0 0.1 0.26 11.5 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGR27316.1 - 0.0015 18.6 0.6 0.48 10.8 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGR27316.1 - 0.12 12.0 2.0 4.5 7.0 0.3 2.6 1 1 1 2 2 2 0 TPR repeat WD40 PF00400.32 EGR27317.1 - 3.3e-10 40.4 3.6 0.01 16.6 0.4 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR27317.1 - 6.7e-09 35.9 0.0 0.004 17.4 0.0 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Utp8 PF10395.9 EGR27317.1 - 0.018 13.6 0.0 0.027 13.0 0.0 1.2 1 0 0 1 1 1 0 Utp8 family Nup160 PF11715.8 EGR27317.1 - 0.26 9.9 1.3 4.9 5.7 0.0 2.4 3 0 0 3 3 3 0 Nucleoporin Nup120/160 zf-CCCH PF00642.24 EGR27318.1 - 8.4e-15 54.3 9.8 4.3e-08 32.9 2.3 2.2 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EGR27318.1 - 1.6e-09 37.4 11.7 7.8e-06 25.6 1.1 2.4 2 1 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGR27318.1 - 4.7e-07 29.6 17.0 0.0022 18.0 2.5 2.8 2 1 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EGR27318.1 - 3.1e-05 24.6 2.5 0.041 14.6 0.1 2.5 2 0 0 2 2 2 2 Torus domain zf-CCCH_2 PF14608.6 EGR27318.1 - 7.6e-05 23.0 10.4 0.0047 17.4 0.8 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger GTSE1_N PF15259.6 EGR27318.1 - 0.15 12.3 1.4 0.19 11.9 1.4 1.2 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 Iso_dh PF00180.20 EGR27319.1 - 1e-20 74.2 0.0 1.2e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Metallophos PF00149.28 EGR27320.1 - 2.4e-32 113.1 1.7 7.1e-32 111.6 0.0 2.4 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase ETF_QO PF05187.13 EGR27321.1 - 3.2e-41 139.7 0.2 7.2e-41 138.6 0.2 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S DAO PF01266.24 EGR27321.1 - 1.6e-07 31.3 0.1 6.1e-05 22.8 0.1 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGR27321.1 - 2.4e-07 30.2 0.0 5.1e-05 22.5 0.1 2.1 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 EGR27321.1 - 8e-07 29.2 0.0 3.6e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGR27321.1 - 4e-06 26.3 0.0 6.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGR27321.1 - 7.7e-05 21.6 0.0 0.00015 20.6 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 EGR27321.1 - 0.00012 21.4 0.0 0.00033 20.0 0.0 1.6 2 0 0 2 2 2 1 Thi4 family Lycopene_cycl PF05834.12 EGR27321.1 - 0.00031 19.9 0.0 0.0011 18.1 0.0 1.7 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EGR27321.1 - 0.00032 20.1 1.3 0.00043 19.6 0.2 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGR27321.1 - 0.00064 19.1 0.0 0.00097 18.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Fer4_7 PF12838.7 EGR27321.1 - 0.00093 19.7 0.8 0.002 18.7 0.8 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain NAD_binding_9 PF13454.6 EGR27321.1 - 0.0012 18.8 0.0 0.0022 18.0 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 EGR27321.1 - 0.005 17.4 0.0 1.6 9.3 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGR27321.1 - 0.0075 15.7 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Fer4_2 PF12797.7 EGR27321.1 - 0.064 13.4 0.4 0.21 11.8 0.4 1.8 1 0 0 1 1 1 0 4Fe-4S binding domain GIDA PF01134.22 EGR27321.1 - 0.071 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Trp_halogenase PF04820.14 EGR27321.1 - 0.1 11.4 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Tryptophan halogenase Coatomer_b_Cpla PF14806.6 EGR27322.1 - 1.4e-39 135.0 0.5 2.2e-39 134.4 0.5 1.3 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 EGR27322.1 - 7.2e-37 126.4 0.2 1.2e-36 125.7 0.2 1.3 1 0 0 1 1 1 1 Coatomer beta C-terminal region DUF2770 PF10968.8 EGR27322.1 - 0.059 13.3 1.9 0.12 12.4 1.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2770) Adaptin_N PF01602.20 EGR27323.1 - 1.5e-67 228.4 29.5 1.8e-67 228.1 29.5 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGR27323.1 - 4e-06 27.0 1.1 4e-06 27.0 1.1 3.3 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGR27323.1 - 0.00047 20.2 0.0 0.19 12.0 0.0 3.8 3 1 1 4 4 4 1 HEAT repeat HEAT_2 PF13646.6 EGR27323.1 - 0.001 19.4 0.0 0.11 12.8 0.0 3.5 2 2 1 3 3 3 1 HEAT repeats DASH_Dad1 PF08649.10 EGR27323.1 - 0.014 15.5 1.1 0.07 13.3 0.2 2.8 3 0 0 3 3 3 0 DASH complex subunit Dad1 Arm PF00514.23 EGR27323.1 - 0.053 13.6 0.0 4.5 7.5 0.0 2.8 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat SPG48 PF14764.6 EGR27323.1 - 0.07 13.6 5.6 0.42 11.1 0.1 3.6 2 1 2 4 4 4 0 AP-5 complex subunit, vesicle trafficking SMC_hinge PF06470.13 EGR27323.1 - 0.24 11.7 4.2 0.31 11.3 0.5 3.0 3 1 0 3 3 3 0 SMC proteins Flexible Hinge Domain DUF5442 PF17514.2 EGR27323.1 - 0.32 11.2 5.2 0.32 11.2 0.9 3.0 2 1 2 4 4 4 0 Family of unknown function (DUF5442) Myb_DNA-bind_3 PF12776.7 EGR27323.1 - 9.8 7.2 7.7 3.6 8.6 0.6 3.4 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain Ribosomal_L24e PF01246.20 EGR27324.1 - 6.7e-31 106.3 6.3 6.7e-31 106.3 6.3 2.0 2 0 0 2 2 2 1 Ribosomal protein L24e Myb_DNA-binding PF00249.31 EGR27325.1 - 9.7e-49 163.3 18.2 1.7e-16 60.2 0.8 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGR27325.1 - 2.6e-39 133.3 17.5 2.3e-18 66.2 1.9 3.6 1 1 2 3 3 3 3 Myb-like DNA-binding domain Yip1 PF04893.17 EGR27325.1 - 2.2e-11 43.8 11.7 3.5e-11 43.1 11.7 1.3 1 0 0 1 1 1 1 Yip1 domain SLIDE PF09111.10 EGR27325.1 - 2e-06 27.8 2.1 0.22 11.5 0.1 3.7 1 1 2 3 3 3 3 SLIDE Myb_DNA-bind_7 PF15963.5 EGR27325.1 - 0.00066 19.5 8.9 0.0009 19.1 2.9 2.6 1 1 0 2 2 2 1 Myb DNA-binding like Rap1_C PF11626.8 EGR27325.1 - 0.0049 16.9 3.3 0.96 9.6 0.3 3.4 1 1 2 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain DUF688 PF05097.12 EGR27325.1 - 0.025 13.8 1.0 0.039 13.1 1.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF688) SANT_DAMP1_like PF16282.5 EGR27325.1 - 0.76 10.0 4.9 1.5 9.1 0.2 3.2 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 Asparaginase PF00710.20 EGR27326.1 - 1.4e-39 135.6 0.0 2.5e-39 134.8 0.0 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Ank_2 PF12796.7 EGR27326.1 - 8.3e-19 68.0 1.3 3.2e-10 40.4 0.2 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Asparaginase_C PF17763.1 EGR27326.1 - 1.7e-17 63.6 0.0 3.1e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_4 PF13637.6 EGR27326.1 - 1.2e-10 41.7 0.1 5.7e-08 33.2 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 EGR27326.1 - 2.7e-10 40.2 0.0 0.0031 17.9 0.0 4.8 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 EGR27326.1 - 1.1e-09 37.8 0.0 0.0013 19.0 0.0 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EGR27326.1 - 8.2e-08 32.4 0.0 8.3e-05 22.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Glyco_hydro_4C PF11975.8 EGR27326.1 - 1.4 9.0 6.0 0.69 10.0 1.8 2.3 2 1 0 2 2 2 0 Family 4 glycosyl hydrolase C-terminal domain DUF1126 PF06565.12 EGR27327.1 - 4.7e-88 289.9 5.4 8.4e-33 112.3 0.3 3.6 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_1 PF00036.32 EGR27327.1 - 0.0014 18.0 0.4 0.0014 18.0 0.4 3.3 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 EGR27327.1 - 0.065 13.1 0.1 0.62 10.0 0.1 2.6 1 1 1 2 2 2 0 EF-hand domain pair Caleosin PF05042.13 EGR27327.1 - 0.07 13.0 0.1 0.37 10.7 0.0 2.1 2 0 0 2 2 2 0 Caleosin related protein EF-hand_6 PF13405.6 EGR27327.1 - 4.7 7.4 5.1 5.8 7.1 0.1 3.2 3 0 0 3 3 3 0 EF-hand domain s48_45 PF07422.13 EGR27327.1 - 5.9 7.5 7.5 9.3 6.9 0.1 3.8 4 1 0 4 4 4 0 Sexual stage antigen s48/45 domain cNMP_binding PF00027.29 EGR27328.1 - 1.7e-21 76.1 0.2 4.9e-16 58.6 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain AstA PF04958.12 EGR27328.1 - 0.024 13.2 0.0 0.032 12.8 0.0 1.1 1 0 0 1 1 1 0 Arginine N-succinyltransferase beta subunit Herpes_U44 PF04533.13 EGR27329.1 - 0.024 14.2 0.1 0.083 12.5 0.0 2.0 2 0 0 2 2 2 0 Herpes virus U44 protein EF-hand_2 PF09068.11 EGR27329.1 - 0.092 12.9 4.3 1.3 9.2 0.1 3.2 2 0 0 2 2 2 0 EF hand PLDc PF00614.22 EGR27330.1 - 2.2e-11 43.4 0.0 5.5e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Phospholipase D Active site motif PLDc_2 PF13091.6 EGR27330.1 - 0.00013 21.8 0.4 1.4 8.8 0.0 3.5 3 0 0 3 3 3 2 PLD-like domain Ank_2 PF12796.7 EGR27331.1 - 2.6e-16 60.0 0.1 1.7e-07 31.7 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGR27331.1 - 3.1e-13 49.6 0.0 9e-08 32.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR27331.1 - 1.5e-09 37.3 0.3 0.037 14.6 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EGR27331.1 - 5.5e-09 36.1 0.2 0.21 12.1 0.0 4.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EGR27331.1 - 1.6e-07 31.7 0.0 0.014 15.9 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) HrpB7 PF09486.10 EGR27331.1 - 0.67 10.3 7.2 1.5 9.2 7.2 1.6 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) C2 PF00168.30 EGR27332.1 - 5.8e-125 408.8 21.2 4.8e-17 62.1 0.0 10.4 10 0 0 10 10 10 9 C2 domain LSDAT_prok PF18171.1 EGR27332.1 - 1.1e-22 80.3 0.0 2.2e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote AAA PF00004.29 EGR27332.1 - 0.0012 19.3 0.0 0.0031 17.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) EF-hand_1 PF00036.32 EGR27332.1 - 0.017 14.6 2.0 0.036 13.6 0.1 2.8 2 0 0 2 2 2 0 EF hand ORC4_C PF14629.6 EGR27332.1 - 0.019 14.3 1.2 0.05 13.0 1.2 1.6 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus C2-C2_1 PF11618.8 EGR27332.1 - 0.057 13.5 0.0 2 8.5 0.0 3.1 3 0 0 3 3 3 0 First C2 domain of RPGR-interacting protein 1 WD40 PF00400.32 EGR27333.1 - 7.6e-42 140.5 14.0 1.5e-08 35.1 0.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR27333.1 - 1.1e-07 32.0 1.9 1 9.7 0.0 5.4 1 1 6 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGR27333.1 - 3.7e-07 29.3 2.6 0.068 11.9 0.1 4.8 2 1 4 6 6 6 4 Nup133 N terminal like WD40_like PF17005.5 EGR27333.1 - 0.01 15.2 0.0 9.3 5.5 0.0 3.1 2 1 1 3 3 3 0 WD40-like domain Nup160 PF11715.8 EGR27333.1 - 0.018 13.7 3.5 2.5 6.6 0.1 4.0 3 2 2 5 5 5 0 Nucleoporin Nup120/160 DUF3050 PF11251.8 EGR27333.1 - 0.057 13.0 0.1 0.099 12.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) Cation_efflux PF01545.21 EGR27335.1 - 5.6e-13 49.1 0.0 1.2e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 Cation efflux family Hydrolase PF00702.26 EGR27335.1 - 0.00087 19.6 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase CLN3 PF02487.17 EGR27335.1 - 0.054 12.5 0.1 0.088 11.8 0.1 1.4 1 0 0 1 1 1 0 CLN3 protein Sec62 PF03839.16 EGR27335.1 - 0.59 9.6 5.2 1.1 8.7 5.2 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Zip PF02535.22 EGR27335.1 - 0.88 8.7 42.0 1.1 8.4 26.9 2.1 1 1 1 2 2 2 0 ZIP Zinc transporter MCM_bind PF09739.9 EGR27335.1 - 2.4 6.5 7.7 3.3 6.0 7.7 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SLC12 PF03522.15 EGR27335.1 - 2.8 6.9 7.8 4.4 6.2 7.8 1.2 1 0 0 1 1 1 0 Solute carrier family 12 SDA1 PF05285.12 EGR27335.1 - 8.8 5.6 20.2 14 5.0 20.2 1.2 1 0 0 1 1 1 0 SDA1 SMC_N PF02463.19 EGR27336.1 - 3.2e-24 85.6 42.0 2.8e-23 82.5 42.0 2.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGR27336.1 - 3.4e-16 59.6 0.0 1.1e-15 58.0 0.0 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EGR27336.1 - 2.5e-11 44.4 17.6 2.5e-11 44.4 17.6 5.2 2 1 3 5 5 5 1 AAA domain AAA_29 PF13555.6 EGR27336.1 - 3.4e-05 23.5 0.0 7.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EGR27336.1 - 3.6e-05 23.7 0.1 3.6e-05 23.7 0.1 3.1 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGR27336.1 - 0.00033 20.5 54.3 0.00033 20.5 54.3 3.3 2 1 2 4 4 4 1 AAA ATPase domain ABC_tran PF00005.27 EGR27336.1 - 0.34 11.4 0.1 0.34 11.4 0.1 4.9 3 1 0 3 3 3 0 ABC transporter gpW PF02831.15 EGR27336.1 - 0.62 10.0 4.3 1.8 8.5 0.1 3.2 3 0 0 3 3 3 0 gpW Amidase PF01425.21 EGR27338.1 - 1.1e-64 219.1 0.0 9.6e-56 189.6 0.0 2.4 2 1 0 2 2 2 2 Amidase SecM PF06558.12 EGR27338.1 - 0.019 15.1 0.2 0.04 14.0 0.2 1.4 1 0 0 1 1 1 0 Secretion monitor precursor protein (SecM) DUF3685 PF12452.8 EGR27338.1 - 0.23 11.1 4.4 0.46 10.2 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) EF1G PF00647.19 EGR27339.1 - 1.7e-28 98.8 1.8 1.7e-28 98.8 1.8 2.4 3 0 0 3 3 3 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 EGR27339.1 - 3e-16 59.5 0.4 1.2e-15 57.6 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGR27339.1 - 1e-12 48.1 0.0 1e-12 48.1 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGR27339.1 - 6.6e-10 39.3 0.0 1.7e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGR27339.1 - 1.8e-08 34.4 0.1 6.1e-08 32.8 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGR27339.1 - 1.5e-06 28.1 0.1 2.8e-06 27.2 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGR27339.1 - 2.9e-06 27.5 0.0 7.5e-06 26.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_5 PF18485.1 EGR27339.1 - 0.0066 16.8 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain DNA_pol_A PF00476.20 EGR27340.1 - 1.3e-75 254.9 6.1 2.6e-73 247.3 1.4 3.2 2 1 0 2 2 2 2 DNA polymerase family A DNA_pol_A_exo1 PF01612.20 EGR27340.1 - 1.7e-19 70.2 1.2 1.1e-14 54.5 0.0 2.6 1 1 0 2 2 2 2 3'-5' exonuclease Pkinase PF00069.25 EGR27342.1 - 5.1e-31 108.0 4.3 5.1e-31 108.0 4.3 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27342.1 - 2.3e-19 69.7 1.8 3.2e-19 69.2 1.8 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase His_Phos_2 PF00328.22 EGR27343.1 - 2.6e-27 96.2 10.8 1.5e-25 90.3 10.8 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) CPSF_A PF03178.15 EGR27344.1 - 2.5e-22 79.6 3.0 3.7e-22 79.0 3.0 1.3 1 0 0 1 1 1 1 CPSF A subunit region ARD PF03079.14 EGR27345.1 - 2.4e-48 164.3 3.6 3.3e-48 163.8 3.6 1.2 1 0 0 1 1 1 1 ARD/ARD' family Aldolase_II PF00596.21 EGR27345.1 - 3.1e-21 76.2 0.0 5e-21 75.5 0.0 1.3 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Cupin_2 PF07883.11 EGR27345.1 - 4.4e-08 32.7 0.0 9.5e-08 31.6 0.0 1.5 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EGR27345.1 - 6.6e-06 26.1 0.2 1.1e-05 25.4 0.2 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain 2OG-FeII_Oxy PF03171.20 EGR27345.1 - 0.0066 16.9 0.0 0.099 13.1 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF585 PF04522.12 EGR27345.1 - 0.047 13.3 0.1 0.4 10.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF585) Cupin_1 PF00190.22 EGR27345.1 - 0.05 13.2 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Cupin Kinesin PF00225.23 EGR27346.1 - 3.5e-98 328.6 6.4 4.5e-98 328.3 6.4 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR27346.1 - 2.4e-19 69.8 1.3 3.6e-19 69.2 0.1 1.9 2 0 0 2 2 2 1 Microtubule binding DUF2181 PF10223.9 EGR27346.1 - 0.023 14.1 0.0 0.067 12.7 0.0 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) CPBP PF02517.16 EGR27347.1 - 7.7e-06 26.2 6.4 7.7e-06 26.2 6.4 2.5 1 1 1 2 2 2 1 CPBP intramembrane metalloprotease DUF3099 PF11298.8 EGR27347.1 - 6.7 6.9 6.1 1.7 8.8 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3099) GAF PF01590.26 EGR27348.1 - 1.7e-23 83.8 0.0 3.9e-18 66.4 0.0 2.4 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 EGR27348.1 - 6.1e-14 52.5 0.0 2.1e-09 37.8 0.0 2.2 2 0 0 2 2 2 2 GAF domain GAF_3 PF13492.6 EGR27348.1 - 1.7e-09 38.1 0.0 1.7e-07 31.6 0.0 2.5 2 0 0 2 2 2 1 GAF domain SpoVT_C PF15714.5 EGR27348.1 - 0.00088 19.3 1.2 0.0029 17.7 0.3 2.4 2 0 0 2 2 2 1 Stage V sporulation protein T C-terminal, transcription factor ATG27 PF09451.10 EGR27349.1 - 1.7e-16 60.9 7.0 4e-15 56.4 2.9 3.0 2 1 0 2 2 2 1 Autophagy-related protein 27 CIMR PF00878.18 EGR27349.1 - 8.1e-05 22.7 1.6 0.016 15.3 0.1 2.7 3 0 0 3 3 3 2 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 EGR27349.1 - 0.00013 21.1 1.9 0.00013 21.1 1.9 2.8 2 1 0 2 2 2 1 Mannose-6-phosphate receptor CCDC24 PF15669.5 EGR27349.1 - 0.018 14.9 2.3 0.028 14.3 2.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family DUF1664 PF07889.12 EGR27349.1 - 0.03 14.4 3.9 0.036 14.1 2.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) PDDEXK_6 PF04720.12 EGR27349.1 - 0.1 12.6 1.5 0.19 11.7 1.5 1.4 1 0 0 1 1 1 0 PDDEXK-like family of unknown function Exonuc_VII_L PF02601.15 EGR27349.1 - 0.2 11.2 5.8 0.3 10.6 5.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3835 PF12927.7 EGR27349.1 - 0.23 12.3 2.3 0.52 11.2 2.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3835) zf-CRD PF17979.1 EGR27350.1 - 4.1e-34 118.0 9.8 4.1e-34 118.0 9.8 3.5 1 1 2 3 3 3 1 Cysteine rich domain with multizinc binding regions FHA PF00498.26 EGR27350.1 - 5.3e-14 52.3 0.2 5.3e-14 52.3 0.2 1.9 2 0 0 2 2 2 1 FHA domain zf-C3HC4_2 PF13923.6 EGR27350.1 - 7.3e-07 28.9 12.0 7.3e-07 28.9 12.0 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-CCHH PF10283.9 EGR27350.1 - 3.6e-06 26.8 5.4 9.1e-06 25.6 5.4 1.8 1 0 0 1 1 1 1 PBZ domain Yop-YscD_cpl PF16697.5 EGR27350.1 - 2.3e-05 24.6 0.2 7.2e-05 23.0 0.0 1.9 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_2 PF13639.6 EGR27350.1 - 0.00011 22.5 11.7 0.00011 22.5 11.7 3.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGR27350.1 - 0.00038 20.3 31.4 0.00039 20.2 10.6 3.1 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGR27350.1 - 0.00052 19.8 13.3 0.00052 19.8 13.3 3.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EGR27350.1 - 0.0018 18.1 4.8 0.0018 18.1 4.8 2.2 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 EGR27350.1 - 0.0048 16.8 12.8 0.0048 16.8 12.8 3.7 3 1 0 3 3 3 1 zinc-RING finger domain Arf PF00025.21 EGR27351.1 - 2.9e-55 186.4 0.0 3.4e-55 186.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EGR27351.1 - 4.2e-15 55.8 0.5 8e-11 41.7 0.1 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EGR27351.1 - 9.5e-11 42.0 0.0 1.6e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGR27351.1 - 7.5e-10 38.5 0.0 1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGR27351.1 - 1.2e-08 35.0 0.0 1.7e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 EGR27351.1 - 6e-08 32.4 0.0 7.5e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGR27351.1 - 4.5e-06 26.2 0.0 6e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGR27351.1 - 6.3e-05 22.6 0.1 0.0032 17.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EGR27351.1 - 0.019 14.7 0.0 0.039 13.7 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 EGR27351.1 - 0.084 13.4 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGR27351.1 - 0.17 12.2 0.0 1.2 9.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 EGR27352.1 - 2.1e-72 243.6 1.3 2.1e-72 243.6 1.3 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27352.1 - 9.3e-43 146.4 0.1 9.3e-43 146.4 0.1 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase POLO_box PF00659.18 EGR27352.1 - 1.7e-21 76.2 5.4 1.2e-20 73.5 0.8 2.9 2 0 0 2 2 2 1 POLO box duplicated region Kinase-like PF14531.6 EGR27352.1 - 1.6e-11 44.1 2.4 6.3e-09 35.6 0.0 2.9 2 1 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 EGR27352.1 - 6.7e-07 28.4 0.1 6.7e-07 28.4 0.1 2.5 3 0 0 3 3 3 1 Fungal protein kinase DUF2722 PF10846.8 EGR27352.1 - 0.0017 17.4 11.1 0.003 16.6 11.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF853 PF05872.12 EGR27352.1 - 0.032 12.8 1.8 0.05 12.2 1.8 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Med3 PF11593.8 EGR27352.1 - 0.12 11.5 18.7 0.2 10.8 18.7 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal ATP-synt_E_2 PF08112.11 EGR27352.1 - 0.29 11.4 11.1 0.036 14.3 5.2 2.7 2 0 0 2 2 2 0 ATP synthase epsilon subunit Arc_PepC_II PF06847.11 EGR27352.1 - 2.6 8.6 5.4 3.2 8.3 1.0 2.8 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Pkinase_Tyr PF07714.17 EGR27353.1 - 5.4e-65 219.3 1.5 7.2e-65 218.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EGR27353.1 - 8.4e-58 195.8 0.0 8.4e-58 195.8 0.0 2.8 3 0 0 3 3 3 1 Protein kinase domain RCC1 PF00415.18 EGR27353.1 - 1e-39 134.9 8.4 2.4e-07 31.2 0.0 8.9 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR27353.1 - 8.3e-34 114.7 20.0 4.3e-11 42.3 0.1 8.4 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat UPF0242 PF06785.11 EGR27353.1 - 0.11 12.6 29.2 1.6 8.8 2.1 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PA26 PF04636.13 EGR27353.1 - 6.3 5.6 11.7 5 5.9 7.0 2.1 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) WD40 PF00400.32 EGR27354.1 - 9.5e-26 89.6 1.0 0.00013 22.6 0.0 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 EGR27354.1 - 8.6e-23 80.4 1.7 8.6e-23 80.4 1.7 2.7 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 EGR27354.1 - 7.9e-07 29.3 5.8 0.098 13.0 0.2 4.5 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Snf7 PF03357.21 EGR27355.1 - 1.2e-16 60.8 34.8 1.2e-16 60.8 33.7 1.5 1 1 0 1 1 1 1 Snf7 Exonuc_VII_L PF02601.15 EGR27355.1 - 0.014 15.0 0.1 0.014 15.0 0.1 2.5 1 1 1 2 2 2 0 Exonuclease VII, large subunit Alph_Pro_TM PF09608.10 EGR27355.1 - 6.1 6.6 9.8 5.1 6.8 2.6 2.2 1 1 1 2 2 2 0 Putative transmembrane protein (Alph_Pro_TM) Ribosomal_S6 PF01250.17 EGR27355.1 - 7 7.0 13.3 1.4 9.3 5.3 2.7 2 1 1 3 3 3 0 Ribosomal protein S6 Ribosomal_S17_N PF16205.5 EGR27356.1 - 2.6e-32 111.0 0.4 4.2e-32 110.3 0.4 1.3 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EGR27356.1 - 0.00014 21.9 0.1 0.00023 21.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 V-ATPase_C PF03223.15 EGR27357.1 - 6.5e-82 275.9 14.7 7.4e-82 275.7 14.7 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF2203 PF09969.9 EGR27357.1 - 0.65 10.7 7.3 2.9 8.6 0.8 3.2 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) PI_PP_I PF18363.1 EGR27357.1 - 4.3 7.6 6.8 0.79 9.9 0.5 2.8 2 1 0 3 3 3 0 Phosphoinositide phosphatase insertion domain AlaDh_PNT_N PF05222.15 EGR27359.1 - 1.6e-20 73.8 0.0 1.3e-19 70.9 0.0 2.4 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain DUF1981 PF09324.10 EGR27359.1 - 4.8e-15 55.2 1.9 4.8e-15 55.2 1.9 6.8 6 1 0 7 7 7 2 Domain of unknown function (DUF1981) S_100 PF01023.19 EGR27359.1 - 0.029 14.1 0.7 0.15 11.8 0.7 2.3 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain COMMD1_N PF17221.3 EGR27359.1 - 0.04 14.2 1.8 0.56 10.5 0.5 3.7 2 0 0 2 2 2 0 COMMD1 N-terminal domain Pkinase PF00069.25 EGR27361.1 - 4.4e-35 121.3 2.5 7.4e-35 120.6 2.5 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27361.1 - 1.4e-19 70.4 0.3 1.9e-19 70.0 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27361.1 - 0.0023 17.3 0.5 0.17 11.1 0.0 2.1 1 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EGR27361.1 - 0.024 13.4 0.0 2.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase ABC1 PF03109.16 EGR27361.1 - 0.11 12.6 0.1 0.32 11.2 0.1 1.8 2 0 0 2 2 2 0 ABC1 family AAA_6 PF12774.7 EGR27362.1 - 1.1e-105 353.3 4.2 1.3e-102 343.1 0.0 3.0 3 0 0 3 3 3 2 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 EGR27362.1 - 3.8e-92 308.3 0.1 3.8e-92 308.3 0.1 3.9 4 0 0 4 4 3 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EGR27362.1 - 2.1e-85 286.6 1.2 5.3e-85 285.3 0.0 2.4 3 0 0 3 3 3 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EGR27362.1 - 8.2e-76 254.0 4.3 8.2e-76 254.0 4.3 3.0 3 0 0 3 3 2 1 ATP-binding dynein motor region AAA_7 PF12775.7 EGR27362.1 - 3.2e-54 183.2 2.7 2.4e-49 167.3 0.0 4.3 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGR27362.1 - 6.3e-49 165.9 0.3 1.9e-48 164.4 0.3 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGR27362.1 - 1.7e-42 144.3 0.0 1.8e-39 134.5 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EGR27362.1 - 4.5e-28 98.3 22.0 4.5e-28 98.3 22.0 2.0 2 1 0 2 2 2 1 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 EGR27362.1 - 1.9e-19 69.7 0.5 1.8e-18 66.6 0.2 2.8 3 0 0 3 3 3 1 AAA+ lid domain AAA_5 PF07728.14 EGR27362.1 - 3e-17 62.9 0.7 4.3e-06 26.8 0.0 6.1 7 0 0 7 7 7 4 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 EGR27362.1 - 3.3e-11 43.4 0.1 3.4e-10 40.1 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 EGR27362.1 - 3.6e-06 27.5 0.0 0.74 10.2 0.0 4.0 3 0 0 3 3 3 1 AAA ATPase domain T2SSE PF00437.20 EGR27362.1 - 3.9e-05 22.8 0.1 0.00043 19.4 0.1 2.4 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA PF00004.29 EGR27362.1 - 0.0036 17.7 0.0 1.2 9.5 0.0 3.3 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGR27362.1 - 0.0052 16.5 0.3 0.035 13.8 0.0 2.5 4 0 0 4 4 3 1 AAA domain AAA_29 PF13555.6 EGR27362.1 - 0.011 15.4 2.8 0.16 11.7 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EGR27362.1 - 0.012 16.0 1.0 0.65 10.4 0.0 3.1 2 0 0 2 2 2 0 RNA helicase Mg_chelatase PF01078.21 EGR27362.1 - 0.047 13.1 0.2 0.17 11.3 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EGR27362.1 - 0.056 14.0 0.0 0.056 14.0 0.0 4.9 5 0 0 5 5 5 0 ABC transporter ResIII PF04851.15 EGR27362.1 - 0.065 13.2 0.0 0.065 13.2 0.0 3.4 3 0 0 3 3 2 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGR27362.1 - 0.071 13.4 0.1 15 5.9 0.1 3.1 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGR27362.1 - 0.31 11.5 0.0 0.31 11.5 0.0 5.8 5 0 0 5 5 5 0 AAA domain AAA_22 PF13401.6 EGR27362.1 - 0.88 9.8 3.4 2 8.7 0.0 3.3 4 0 0 4 4 3 0 AAA domain DHC_N1 PF08385.12 EGR27363.1 - 2e-126 422.9 7.0 4.2e-67 227.1 1.4 5.2 3 3 2 5 5 5 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EGR27363.1 - 2e-110 369.6 21.5 2e-110 369.6 21.5 4.2 4 1 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 DUF2974 PF11187.8 EGR27363.1 - 0.0025 17.4 1.0 0.0025 17.4 1.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2974) EPO_TPO PF00758.18 EGR27363.1 - 0.13 12.3 4.5 4 7.4 0.8 3.4 3 0 0 3 3 3 0 Erythropoietin/thrombopoietin PMC2NT PF08066.12 EGR27363.1 - 1.3 9.8 6.4 3.4 8.4 0.1 4.7 3 0 0 3 3 3 0 PMC2NT (NUC016) domain Ribosomal_S30 PF04758.14 EGR27364.1 - 8.4e-23 80.3 5.6 1e-22 80.1 5.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 DmsC PF04976.12 EGR27365.1 - 0.052 13.0 0.2 0.053 13.0 0.2 1.1 1 0 0 1 1 1 0 DMSO reductase anchor subunit (DmsC) BPL_LplA_LipB PF03099.19 EGR27366.1 - 0.00036 20.4 0.0 0.00074 19.4 0.0 1.6 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Cu_bind_CorA PF18252.1 EGR27366.1 - 0.071 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Copper(I)-binding protein CorA FAD_binding_3 PF01494.19 EGR27367.1 - 9.9e-16 57.9 0.0 1.8e-14 53.8 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain K_oxygenase PF13434.6 EGR27367.1 - 0.082 12.0 0.0 0.15 11.1 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Peptidase_S11 PF00768.20 EGR27368.1 - 1.7e-38 132.4 1.5 5.1e-38 130.9 1.5 1.7 1 1 0 1 1 1 1 D-alanyl-D-alanine carboxypeptidase DAD PF02109.16 EGR27368.1 - 7.6 6.9 9.7 1.3 9.4 2.0 2.5 2 0 0 2 2 2 0 DAD family Peptidase_C2 PF00648.21 EGR27369.1 - 3.4e-64 216.7 0.0 4.9e-64 216.2 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EGR27369.1 - 0.0014 18.9 0.1 0.0041 17.4 0.0 1.8 2 0 0 2 2 2 1 Calpain large subunit, domain III MORN PF02493.20 EGR27370.1 - 1.9e-39 131.2 44.1 2.4e-07 30.2 0.1 8.2 8 0 0 8 8 8 8 MORN repeat ID PF18543.1 EGR27370.1 - 0.63 10.1 13.5 21 5.2 0.1 5.3 6 0 0 6 6 6 0 Intracellular delivery domain YusW PF14039.6 EGR27370.1 - 0.73 10.4 5.4 15 6.2 0.3 3.2 3 0 0 3 3 3 0 YusW-like protein Citrus_P18 PF05520.11 EGR27370.1 - 0.8 9.4 2.3 45 3.7 0.0 3.1 2 2 1 3 3 3 0 Citrus tristeza virus P18 protein DUF5342 PF17277.2 EGR27370.1 - 7.5 7.0 10.2 4.2 7.8 0.4 3.7 2 1 1 4 4 4 0 Family of unknown function (DUF5342) Peptidase_M8 PF01457.16 EGR27371.1 - 1.2e-37 129.8 10.5 4.3e-35 121.4 0.2 2.3 1 1 1 2 2 2 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR27371.1 - 4.1e-08 33.1 9.2 4.1e-08 33.1 9.2 3.4 3 0 0 3 3 3 1 Tenascin EGF domain FlxA PF14282.6 EGR27371.1 - 0.45 10.5 7.6 1.6 8.8 7.6 1.9 1 0 0 1 1 1 0 FlxA-like protein SHR-BD PF06650.12 EGR27372.1 - 5.8e-11 42.3 2.5 5.8e-11 42.3 2.5 4.4 3 1 0 4 4 4 2 SHR-binding domain of vacuolar-sorting associated protein 13 HTH_Tnp_Tc3_2 PF01498.18 EGR27372.1 - 0.07 13.4 0.4 0.23 11.7 0.4 1.8 1 0 0 1 1 1 0 Transposase tRNA_bind PF01588.20 EGR27374.1 - 0.053 13.6 0.1 0.16 12.1 0.0 1.7 2 0 0 2 2 2 0 Putative tRNA binding domain BT1 PF03092.16 EGR27375.1 - 9.4e-41 139.6 4.1 6.3e-28 97.3 2.4 2.0 1 1 1 2 2 2 2 BT1 family MFS_1 PF07690.16 EGR27375.1 - 1.6e-05 24.0 4.4 0.0054 15.7 0.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Glyco_transf_5 PF08323.11 EGR27376.1 - 2.7e-38 132.0 0.0 8.2e-38 130.5 0.0 1.8 1 0 0 1 1 1 1 Starch synthase catalytic domain AMPK1_CBM PF16561.5 EGR27376.1 - 2.8e-18 65.9 0.1 1.1e-17 64.1 0.1 2.0 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Glycos_transf_1 PF00534.20 EGR27376.1 - 6.8e-16 58.3 0.0 4.3e-15 55.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGR27376.1 - 7e-10 39.4 0.0 1.6e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGR27376.1 - 0.00013 22.0 0.0 0.00048 20.2 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 CBM_48 PF02922.18 EGR27376.1 - 0.0035 17.7 0.1 0.017 15.4 0.1 2.3 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Malt_amylase_C PF16657.5 EGR27376.1 - 0.087 13.0 0.1 0.32 11.1 0.1 2.0 2 0 0 2 2 2 0 Maltogenic Amylase, C-terminal domain Glyco_trans_4_4 PF13579.6 EGR27376.1 - 0.12 12.8 0.0 0.23 11.9 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain DEAD PF00270.29 EGR27377.1 - 4.2e-30 104.8 1.4 5.5e-30 104.4 0.3 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR27377.1 - 3.8e-18 65.9 0.8 3.8e-18 65.9 0.8 3.0 2 2 1 3 3 3 1 Helicase conserved C-terminal domain AAA_19 PF13245.6 EGR27377.1 - 5.6e-06 26.8 0.2 2.1e-05 24.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 EGR27377.1 - 7.6e-06 25.7 1.2 1.4e-05 24.8 1.2 1.5 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain Pkinase PF00069.25 EGR27379.1 - 2.5e-53 181.1 0.4 1.2e-52 178.9 0.4 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27379.1 - 8.3e-24 84.3 0.9 5.9e-23 81.5 0.9 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27379.1 - 0.0011 18.3 0.1 0.0022 17.4 0.1 1.5 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EGR27379.1 - 0.0036 16.4 0.4 0.0084 15.2 0.0 1.7 2 0 0 2 2 2 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EGR27379.1 - 0.0098 14.7 0.0 0.018 13.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Formyl_trans_N PF00551.19 EGR27382.1 - 1.1e-27 97.0 0.0 1.5e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 EGR27382.1 - 3.7e-05 23.9 0.0 0.00012 22.2 0.0 1.8 2 0 0 2 2 2 1 Formyl transferase, C-terminal domain NIF PF03031.18 EGR27383.1 - 7.5e-48 162.2 0.6 1.4e-47 161.3 0.0 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase p450 PF00067.22 EGR27384.1 - 2.3e-59 201.3 0.1 2.7e-59 201.1 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 E1-E2_ATPase PF00122.20 EGR27385.1 - 6.6e-30 104.0 0.0 3.1e-29 101.8 0.0 2.2 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EGR27385.1 - 3.8e-13 50.2 0.1 2.4e-06 28.0 0.1 3.5 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGR27385.1 - 1.3e-08 34.8 4.3 1.4e-07 31.5 0.0 3.8 3 0 0 3 3 3 1 Cation transport ATPase (P-type) TMF_DNA_bd PF12329.8 EGR27385.1 - 0.0023 17.9 17.2 0.0023 17.9 17.2 12.4 5 2 9 14 14 14 2 TATA element modulatory factor 1 DNA binding HIP1_clath_bdg PF16515.5 EGR27385.1 - 0.0026 18.3 14.8 0.0026 18.3 14.8 11.5 5 2 5 11 11 11 2 Clathrin-binding domain of Huntingtin-interacting protein 1 Phage_holin_2_4 PF16082.5 EGR27385.1 - 0.6 9.9 2.8 0.31 10.8 0.1 1.9 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Cation_ATPase_N PF00690.26 EGR27386.1 - 0.00014 21.5 0.0 0.00024 20.7 0.0 1.4 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus PI3_PI4_kinase PF00454.27 EGR27387.1 - 2.1e-32 112.9 7.7 3e-23 82.9 0.5 3.1 2 2 1 4 4 4 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGR27387.1 - 0.0001 21.8 5.3 0.0001 21.8 5.3 2.4 3 0 0 3 3 3 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 EGR27387.1 - 0.017 14.5 0.0 0.025 13.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Response_reg PF00072.24 EGR27388.1 - 2.6e-18 66.2 1.6 4.4e-18 65.5 0.1 2.1 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 EGR27388.1 - 1.3e-15 57.9 0.4 1.3e-15 57.9 0.4 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGR27388.1 - 0.00041 20.2 0.2 0.0013 18.6 0.1 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2183 PF09949.9 EGR27388.1 - 0.071 13.5 4.7 1.1 9.6 0.4 2.9 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2183) HAGH_C PF16123.5 EGR27389.1 - 6.5e-14 52.2 0.6 1.2e-13 51.3 0.6 1.4 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Fer4_24 PF18109.1 EGR27391.1 - 2.1 8.7 5.4 11 6.4 0.7 3.6 3 0 0 3 3 3 0 Ferredoxin I 4Fe-4S cluster domain Ank_2 PF12796.7 EGR27392.1 - 2.1e-19 69.9 0.5 5.4e-13 49.3 0.1 2.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGR27392.1 - 2.3e-18 66.3 1.1 1.5e-09 38.2 0.1 3.1 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR27392.1 - 4.1e-14 51.3 0.1 4.2e-07 29.8 0.0 3.5 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EGR27392.1 - 6.8e-14 51.6 0.2 3.5e-08 33.5 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EGR27392.1 - 2.4e-10 40.4 0.0 0.00035 20.8 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) FKBP_C PF00254.28 EGR27393.1 - 0.00014 22.1 0.3 0.0094 16.3 0.0 3.0 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase EF-hand_1 PF00036.32 EGR27394.1 - 5.1e-15 53.8 5.7 1.7e-07 30.3 0.2 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EGR27394.1 - 5.2e-13 47.8 1.4 5.5e-06 25.9 0.1 2.8 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EGR27394.1 - 3e-12 46.8 0.2 4.6e-12 46.2 0.2 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGR27394.1 - 4.4e-10 38.6 4.0 9e-06 25.0 0.0 2.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EGR27394.1 - 7.3e-09 35.3 2.6 0.00081 19.2 0.3 2.4 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGR27394.1 - 0.00012 22.4 0.2 0.00023 21.4 0.2 1.5 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EGR27394.1 - 0.0017 18.6 0.1 0.0024 18.1 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 EGR27394.1 - 0.035 14.1 3.0 0.86 9.6 0.2 2.1 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Transket_pyr PF02779.24 EGR27395.1 - 8.3e-42 142.9 0.0 1.2e-41 142.4 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGR27395.1 - 6.2e-35 119.8 0.0 1.5e-34 118.5 0.0 1.6 2 0 0 2 2 2 1 Transketolase, C-terminal domain Ribosomal_L13 PF00572.18 EGR27396.1 - 1.3e-32 112.6 1.3 1.5e-32 112.5 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L13 CBF PF03914.17 EGR27397.1 - 2.8e-35 121.8 19.2 9.1e-19 68.1 0.2 4.2 4 0 0 4 4 4 2 CBF/Mak21 family ABC_tran PF00005.27 EGR27398.1 - 2.8e-29 102.4 0.1 5.6e-29 101.4 0.1 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGR27398.1 - 3e-16 59.5 26.4 1.4e-15 57.3 26.4 2.2 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGR27398.1 - 2.8e-11 43.8 0.0 1.5e-06 28.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGR27398.1 - 1.7e-05 24.7 3.1 0.13 12.0 0.1 3.5 2 1 0 3 3 3 2 AAA ATPase domain SMC_N PF02463.19 EGR27398.1 - 0.00014 21.4 0.3 0.0013 18.2 0.3 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGR27398.1 - 0.00027 20.9 0.1 0.00063 19.7 0.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EGR27398.1 - 0.00051 19.7 0.2 0.0012 18.6 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EGR27398.1 - 0.0007 20.2 0.6 0.0019 18.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EGR27398.1 - 0.0017 18.4 0.3 0.0065 16.6 0.3 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Mg_chelatase PF01078.21 EGR27398.1 - 0.025 14.0 0.0 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EGR27398.1 - 0.093 13.1 0.0 0.29 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain KdpD PF02702.17 EGR27398.1 - 0.1 12.1 0.1 0.21 11.0 0.1 1.5 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain Vps39_1 PF10366.9 EGR27399.1 - 0.42 10.9 5.3 0.15 12.4 1.3 2.3 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 LRR_6 PF13516.6 EGR27400.1 - 2.9e-09 36.2 87.6 0.51 10.5 0.0 21.5 24 0 0 24 24 24 8 Leucine Rich repeat LRR_4 PF12799.7 EGR27400.1 - 5.8e-09 36.1 140.0 1.1e-05 25.6 0.7 19.1 14 5 6 20 20 20 11 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGR27400.1 - 0.00096 19.4 95.2 0.4 11.4 0.0 22.1 25 1 0 25 25 25 6 Leucine Rich Repeat LRR_8 PF13855.6 EGR27400.1 - 0.0015 18.2 13.7 0.0048 16.6 0.8 17.3 13 4 4 18 18 18 5 Leucine rich repeat PI3_PI4_kinase PF00454.27 EGR27401.1 - 8.6e-54 183.0 2.4 8.5e-53 179.7 0.4 3.3 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGR27401.1 - 2.6e-39 134.5 2.2 7.2e-39 133.1 2.2 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 EGR27401.1 - 5.3e-14 52.3 0.1 1.9e-13 50.5 0.1 1.9 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 EGR27401.1 - 2.9e-08 33.8 0.5 2.9e-08 33.8 0.5 3.1 2 1 0 2 2 2 1 PI3-kinase family, ras-binding domain DUF4135 PF13575.6 EGR27401.1 - 0.023 14.0 0.0 0.043 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) LMBR1 PF04791.16 EGR27402.1 - 9.3e-26 90.8 5.8 1.1e-25 90.6 5.8 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein WD40 PF00400.32 EGR27403.1 - 1.3e-31 108.1 12.3 1.9e-06 28.5 0.1 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat PRP4 PF08799.11 EGR27403.1 - 1.3e-14 53.4 0.5 2.8e-14 52.4 0.5 1.6 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 EGR27403.1 - 1.3e-08 35.0 0.1 0.025 14.8 0.0 4.9 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGR27403.1 - 5.5e-05 22.0 0.3 0.45 9.1 0.0 3.4 2 2 1 3 3 3 3 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 EGR27403.1 - 0.0034 17.4 0.2 0.048 13.7 0.0 2.8 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Ribosomal_L1 PF00687.21 EGR27405.1 - 1e-40 139.6 0.8 1.5e-40 139.1 0.2 1.5 1 1 0 1 1 1 1 Ribosomal protein L1p/L10e family Kinesin PF00225.23 EGR27406.1 - 3.1e-96 322.2 4.0 3.1e-96 322.2 4.0 2.7 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EGR27406.1 - 5.9e-20 71.7 0.2 5.9e-20 71.7 0.2 3.2 3 2 0 3 3 3 1 Microtubule binding FHA PF00498.26 EGR27406.1 - 5.6e-06 26.6 0.8 3.1e-05 24.2 0.1 2.8 3 0 0 3 3 3 1 FHA domain Yop-YscD_cpl PF16697.5 EGR27406.1 - 0.092 13.1 0.0 0.42 11.0 0.0 2.2 1 1 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain KIF1B PF12423.8 EGR27406.1 - 0.11 12.9 3.5 2.4 8.7 0.0 3.4 2 0 0 2 2 2 0 Kinesin protein 1B Tyrosinase PF00264.20 EGR27406.1 - 1.9 8.7 11.7 0.86 9.8 0.4 2.7 2 0 0 2 2 2 0 Common central domain of tyrosinase DUF489 PF04356.12 EGR27406.1 - 4.1 7.4 15.0 9.5 6.2 0.6 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF489) Oxysterol_BP PF01237.18 EGR27407.1 - 1e-35 123.3 7.3 1.3e-30 106.5 0.3 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein RNA_GG_bind PF10258.9 EGR27407.1 - 0.068 13.2 0.1 0.25 11.4 0.0 2.0 2 0 0 2 2 2 0 PHAX RNA-binding domain SURF1 PF02104.15 EGR27408.1 - 2.1e-10 41.2 0.0 2.8e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 SURF1 family malic PF00390.19 EGR27409.1 - 2e-22 79.9 5.6 6.2e-15 55.5 1.9 4.0 3 1 0 3 3 3 2 Malic enzyme, N-terminal domain Malic_M PF03949.15 EGR27409.1 - 1.7e-20 73.4 6.1 1.4e-19 70.4 6.1 2.4 1 1 0 1 1 1 1 Malic enzyme, NAD binding domain ELFV_dehydrog PF00208.21 EGR27409.1 - 0.0036 17.0 1.3 0.0063 16.3 0.0 2.0 3 0 0 3 3 3 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CBAH PF02275.18 EGR27409.1 - 0.026 14.2 0.5 0.047 13.3 0.0 1.7 2 0 0 2 2 2 0 Linear amide C-N hydrolases, choloylglycine hydrolase family PLA1 PF02253.15 EGR27409.1 - 0.097 12.3 0.1 0.16 11.5 0.1 1.4 1 0 0 1 1 1 0 Phospholipase A1 Pkinase PF00069.25 EGR27410.1 - 7.2e-59 199.3 0.1 8.7e-59 199.0 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27410.1 - 3.4e-30 105.2 0.0 4.5e-30 104.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR27410.1 - 9.6e-06 24.6 0.0 1.3e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EGR27410.1 - 0.00019 20.6 0.0 0.00033 19.8 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 EGR27410.1 - 0.00022 20.7 0.0 0.00031 20.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGR27410.1 - 0.0014 17.7 0.5 0.002 17.2 0.5 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Tubulin PF00091.25 EGR27410.1 - 0.14 12.3 0.2 0.22 11.7 0.2 1.4 1 0 0 1 1 1 0 Tubulin/FtsZ family, GTPase domain AMP-binding PF00501.28 EGR27412.1 - 2.2e-70 237.4 0.0 2.7e-70 237.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGR27412.1 - 1.9e-11 44.8 0.0 3.7e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding_C_2 PF14535.6 EGR27412.1 - 0.15 12.4 0.6 0.48 10.8 0.1 2.2 2 0 0 2 2 2 0 AMP-binding enzyme C-terminal domain RRM_1 PF00076.22 EGR27413.1 - 4.2e-17 61.7 0.1 6.5e-17 61.1 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGR27413.1 - 2.9e-08 33.3 0.0 3.4e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Phage_TAC_13 PF16459.5 EGR27413.1 - 0.012 16.0 0.0 0.019 15.4 0.0 1.3 1 0 0 1 1 1 0 Phage tail assembly chaperone, TAC RRM_8 PF11835.8 EGR27413.1 - 0.1 12.9 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 RRM-like domain RRM_7 PF16367.5 EGR27413.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.8 1 1 0 1 1 1 0 RNA recognition motif RRM_occluded PF16842.5 EGR27413.1 - 0.15 12.0 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Ribosomal_L22e PF01776.17 EGR27414.1 - 1.7e-42 144.2 3.6 2e-42 144.0 3.6 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Telomerase_RBD PF12009.8 EGR27414.1 - 0.034 14.2 1.8 0.048 13.8 1.7 1.3 1 1 0 1 1 1 0 Telomerase ribonucleoprotein complex - RNA binding domain DUF2281 PF10047.9 EGR27414.1 - 0.16 12.7 1.4 3.3 8.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2281) Kinesin PF00225.23 EGR27415.1 - 4.7e-91 305.2 1.5 4.7e-91 305.2 1.5 4.1 2 1 1 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 EGR27415.1 - 2.2e-19 69.9 0.2 2.2e-19 69.9 0.2 4.3 2 1 1 4 4 4 1 Microtubule binding XPG_N PF00752.17 EGR27416.1 - 5.9e-26 90.9 0.0 5.9e-26 90.9 0.0 3.6 3 0 0 3 3 3 1 XPG N-terminal domain XPG_I PF00867.18 EGR27416.1 - 1.5e-25 89.4 0.0 1.5e-25 89.4 0.0 5.5 3 1 2 5 5 5 1 XPG I-region HHH_2 PF12826.7 EGR27416.1 - 0.0046 17.0 0.0 0.026 14.6 0.0 2.3 2 0 0 2 2 2 1 Helix-hairpin-helix motif HEAT_EZ PF13513.6 EGR27417.1 - 1.5e-10 41.4 0.0 4.5e-06 27.0 0.0 5.1 5 0 0 5 5 5 2 HEAT-like repeat HEAT PF02985.22 EGR27417.1 - 2e-10 40.0 5.1 0.051 13.9 0.0 8.8 12 0 0 12 12 12 2 HEAT repeat Vac14_Fab1_bd PF12755.7 EGR27417.1 - 4.8e-10 39.9 2.0 0.0034 17.9 0.0 6.1 5 1 2 7 7 7 3 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EGR27417.1 - 2.3e-08 34.3 0.0 0.002 18.5 0.0 4.8 4 2 1 5 5 5 3 HEAT repeats UME PF08064.13 EGR27417.1 - 1.1e-06 28.4 2.2 0.77 9.7 0.0 5.1 4 1 1 5 5 5 2 UME (NUC010) domain CLASP_N PF12348.8 EGR27417.1 - 0.0017 18.0 9.2 0.24 11.0 0.0 5.5 4 2 2 6 6 6 2 CLASP N terminal TAF6_C PF07571.13 EGR27417.1 - 0.0073 16.6 0.1 1 9.7 0.0 4.1 3 1 0 3 3 3 1 TAF6 C-terminal HEAT repeat domain Ipi1_N PF12333.8 EGR27417.1 - 0.3 11.7 1.3 32 5.2 0.0 4.2 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation TTRAP PF14203.6 EGR27417.1 - 1 9.4 10.7 0.53 10.3 0.5 4.7 5 0 0 5 5 5 0 Putative tranposon-transfer assisting protein zf-CCHC PF00098.23 EGR27418.1 - 0.006 16.6 3.7 0.015 15.3 3.7 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EGR27418.1 - 7.9 6.3 8.3 0.36 10.6 1.3 2.3 2 0 0 2 2 2 0 Zinc knuckle Tim17 PF02466.19 EGR27419.1 - 1.4e-14 54.4 0.1 3e-14 53.3 0.1 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Pkinase PF00069.25 EGR27420.1 - 5.9e-27 94.7 0.1 5.9e-27 94.7 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27420.1 - 1.1e-17 64.2 0.0 2.1e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR27420.1 - 0.00015 20.7 0.1 0.00015 20.7 0.1 2.1 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGR27421.1 - 4.6e-34 118.4 0.0 8e-34 117.6 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 EGR27421.1 - 7e-33 114.0 0.7 9.8e-33 113.5 0.7 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGR27421.1 - 4.1e-19 68.6 0.0 8e-19 67.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGR27421.1 - 8.3e-10 39.1 0.1 1.3e-09 38.4 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGR27421.1 - 4.3e-09 37.0 0.0 8.4e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain RIO1 PF01163.22 EGR27421.1 - 0.0075 15.9 0.1 0.18 11.4 0.0 2.6 2 1 0 2 2 2 1 RIO1 family Acyl-CoA_ox_N PF14749.6 EGR27421.1 - 2.5 8.7 6.5 9.8 6.8 0.0 3.5 3 0 0 3 3 3 0 Acyl-coenzyme A oxidase N-terminal EF_TS PF00889.19 EGR27422.1 - 0.028 14.0 5.0 0.049 13.2 5.0 1.4 1 0 0 1 1 1 0 Elongation factor TS Amidase PF01425.21 EGR27422.1 - 0.11 11.4 1.7 0.13 11.2 1.7 1.1 1 0 0 1 1 1 0 Amidase NCE101 PF11654.8 EGR27423.1 - 0.0036 17.0 1.9 0.11 12.3 0.0 2.9 3 0 0 3 3 3 1 Non-classical export protein 1 DUF2085 PF09858.9 EGR27423.1 - 0.03 14.8 0.1 0.03 14.8 0.1 2.9 1 1 1 3 3 3 0 Predicted membrane protein (DUF2085) Oxidored_q3 PF00499.20 EGR27423.1 - 5.1 6.8 11.5 3.4 7.4 0.4 2.9 3 1 0 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 FSAP_sig_propep PF03032.15 EGR27423.1 - 7 6.8 0.0 7 6.8 0.0 2.9 3 1 0 3 3 3 0 Frog skin active peptide family signal and propeptide FAA_hydrolase PF01557.18 EGR27424.1 - 6.6e-34 117.5 0.0 7.3e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family EF-hand_7 PF13499.6 EGR27425.1 - 1.7e-06 28.4 5.7 8.3e-06 26.2 0.2 3.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EGR27425.1 - 1.6e-05 24.1 12.7 0.00032 20.0 0.2 4.2 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 EGR27425.1 - 0.00022 20.9 8.9 0.0061 16.4 0.2 4.0 4 1 1 5 5 5 2 EF-hand domain EF-hand_8 PF13833.6 EGR27425.1 - 0.0076 16.1 1.7 0.23 11.4 0.1 3.5 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 EGR27425.1 - 0.064 12.8 0.9 2.4 7.8 0.1 2.7 2 0 0 2 2 2 0 EF hand FtsH_ext PF06480.15 EGR27425.1 - 0.46 10.8 18.4 0.27 11.6 2.4 4.5 3 1 1 4 4 4 0 FtsH Extracellular Cdc6_C PF09079.11 EGR27426.1 - 0.051 13.6 0.2 2.7 8.0 0.1 2.4 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain MA3 PF02847.17 EGR27426.1 - 3.3 7.7 11.9 2 8.4 0.5 3.3 2 1 0 3 3 3 0 MA3 domain NAD_binding_10 PF13460.6 EGR27428.1 - 0.17 11.8 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Ribosomal_L22 PF00237.19 EGR27429.1 - 6.4e-11 42.4 0.0 8.6e-11 42.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e NAD_Gly3P_dh_N PF01210.23 EGR27429.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus PHM7_cyt PF14703.6 EGR27430.1 - 4.5e-05 23.8 8.1 4.5e-05 23.8 8.1 2.3 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter WD40 PF00400.32 EGR27431.1 - 2.5e-06 28.1 6.5 0.16 12.9 0.4 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR27431.1 - 0.0013 19.0 1.9 3.4 8.0 0.0 4.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DHO_dh PF01180.21 EGR27432.1 - 1.7e-27 96.4 0.0 3.1e-27 95.6 0.0 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Fer4_20 PF14691.6 EGR27432.1 - 3.1e-27 94.6 6.2 3.1e-27 94.6 6.2 2.8 2 0 0 2 2 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_21 PF14697.6 EGR27432.1 - 1.9e-18 66.4 9.1 1.9e-18 66.4 9.1 3.8 3 1 0 3 3 2 1 4Fe-4S dicluster domain Pyr_redox_2 PF07992.14 EGR27432.1 - 4.6e-13 49.0 0.0 7.7e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGR27432.1 - 1.1e-07 32.3 0.0 5.5e-05 23.6 0.0 3.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_10 PF13237.6 EGR27432.1 - 6.1e-06 26.3 10.1 6.1e-06 26.3 10.1 3.8 3 1 0 3 3 3 1 4Fe-4S dicluster domain Dus PF01207.17 EGR27432.1 - 6.9e-06 25.4 0.1 1.3e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Fer4_7 PF12838.7 EGR27432.1 - 2e-05 25.1 9.2 2e-05 25.1 9.2 4.3 4 1 1 5 5 4 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGR27432.1 - 4.5e-05 23.5 7.9 4.5e-05 23.5 7.9 3.5 2 1 2 4 4 3 1 4Fe-4S dicluster domain NAD_binding_8 PF13450.6 EGR27432.1 - 5.2e-05 23.4 0.0 0.00013 22.1 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FMN_dh PF01070.18 EGR27432.1 - 0.00019 20.6 0.3 0.0071 15.4 0.1 2.4 2 1 0 2 2 2 1 FMN-dependent dehydrogenase Pyr_redox_3 PF13738.6 EGR27432.1 - 0.00028 20.3 0.1 0.57 9.4 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Fer4 PF00037.27 EGR27432.1 - 0.00093 18.9 25.4 0.00094 18.9 5.1 4.0 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_6 PF12837.7 EGR27432.1 - 0.013 15.5 1.4 0.013 15.5 1.4 4.8 5 0 0 5 5 3 0 4Fe-4S binding domain Fer4_2 PF12797.7 EGR27432.1 - 0.017 15.2 2.7 0.017 15.2 2.7 5.2 5 0 0 5 5 4 0 4Fe-4S binding domain Fer4_4 PF12800.7 EGR27432.1 - 0.022 15.2 4.1 0.022 15.2 4.1 4.7 5 0 0 5 5 3 0 4Fe-4S binding domain Thi4 PF01946.17 EGR27432.1 - 0.029 13.6 0.0 0.096 11.9 0.0 1.8 2 0 0 2 2 2 0 Thi4 family Fer4_17 PF13534.6 EGR27432.1 - 0.68 10.5 29.1 0.096 13.2 1.1 4.7 4 0 0 4 4 3 0 4Fe-4S dicluster domain Fer4_22 PF17179.4 EGR27432.1 - 2.2 9.2 19.6 3.6 8.5 0.2 4.5 4 0 0 4 4 3 0 4Fe-4S dicluster domain NIF PF03031.18 EGR27433.1 - 8.1e-26 90.7 0.3 8.1e-26 90.7 0.3 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase CDC45 PF02724.14 EGR27433.1 - 0.0003 19.2 15.5 0.0003 19.2 15.5 1.1 1 0 0 1 1 1 1 CDC45-like protein SLC12 PF03522.15 EGR27433.1 - 0.0022 17.1 13.1 0.0023 17.0 13.1 1.2 1 0 0 1 1 1 1 Solute carrier family 12 Cwf_Cwc_15 PF04889.12 EGR27433.1 - 0.0044 16.8 25.9 0.0064 16.3 25.9 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein MIF4G_like_2 PF09090.11 EGR27433.1 - 0.038 13.5 13.1 0.049 13.1 13.1 1.2 1 0 0 1 1 1 0 MIF4G like FAM60A PF15396.6 EGR27433.1 - 0.3 11.1 16.3 0.43 10.5 16.3 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Hydin_ADK PF17213.3 EGR27433.1 - 0.42 10.9 16.2 0.69 10.2 16.2 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF3807 PF12720.7 EGR27433.1 - 0.63 10.3 30.6 0.91 9.8 30.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF2052 PF09747.9 EGR27433.1 - 0.64 10.1 30.1 1.1 9.4 30.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) AAA_13 PF13166.6 EGR27433.1 - 1.1 7.9 26.2 1.4 7.5 26.2 1.1 1 0 0 1 1 1 0 AAA domain DUF4746 PF15928.5 EGR27433.1 - 1.4 8.2 28.8 3.3 7.1 28.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) BORG_CEP PF14957.6 EGR27433.1 - 2 9.6 13.8 3.2 8.9 13.8 1.3 1 0 0 1 1 1 0 Cdc42 effector PAT1 PF09770.9 EGR27433.1 - 2.5 6.3 22.5 2.9 6.0 22.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4175 PF13779.6 EGR27433.1 - 2.9 5.7 22.8 3.3 5.5 22.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Hid1 PF12722.7 EGR27433.1 - 2.9 5.9 18.7 3.6 5.6 18.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.12 EGR27433.1 - 3 7.6 37.2 5.3 6.8 37.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4045 PF13254.6 EGR27433.1 - 3 7.4 23.3 3.7 7.1 23.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CCSAP PF15748.5 EGR27433.1 - 6 7.0 27.2 8.5 6.5 27.2 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated GBP_C PF02841.14 EGR27433.1 - 6.5 6.1 41.1 11 5.3 41.1 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF5427 PF10310.9 EGR27433.1 - 6.8 5.5 31.9 9.4 5.1 31.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) DUF2828 PF11443.8 EGR27433.1 - 7.1 4.6 23.4 9.9 4.1 23.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Membralin PF09746.9 EGR27433.1 - 7.1 5.6 15.8 12 4.8 15.8 1.4 1 0 0 1 1 1 0 Tumour-associated protein CDC27 PF09507.10 EGR27433.1 - 8.1 5.7 40.8 9.6 5.5 40.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF913 PF06025.12 EGR27433.1 - 9.3 5.1 15.8 14 4.5 15.8 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) UCH PF00443.29 EGR27434.1 - 1.2e-45 156.0 12.1 1.2e-45 156.0 12.1 5.4 6 1 0 6 6 6 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR27434.1 - 4e-25 89.1 10.4 4e-25 89.1 10.4 4.7 5 1 1 6 6 6 1 Ubiquitin carboxyl-terminal hydrolase CpXC PF14353.6 EGR27434.1 - 0.032 14.3 2.3 0.25 11.4 0.2 3.8 3 0 0 3 3 3 0 CpXC protein B9-C2 PF07162.11 EGR27435.1 - 7.9e-43 146.6 0.0 9.1e-43 146.4 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Glycos_transf_2 PF00535.26 EGR27436.1 - 2.3e-20 73.1 3.1 1.3e-19 70.6 3.1 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGR27436.1 - 0.00013 21.9 0.0 0.00028 20.9 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 DUF4455 PF14643.6 EGR27437.1 - 2.4e-115 385.9 64.3 2.4e-115 385.9 64.3 4.8 4 1 0 4 4 4 1 Domain of unknown function (DUF4455) DUF4456 PF14644.6 EGR27437.1 - 7.5e-53 179.3 7.8 7.5e-53 179.3 7.8 7.6 7 2 2 9 9 9 1 Domain of unknown function (DUF4456) Intron_maturas2 PF01348.21 EGR27437.1 - 0.055 13.4 0.2 0.055 13.4 0.2 3.9 4 0 0 4 4 4 0 Type II intron maturase Sdh5 PF03937.16 EGR27437.1 - 0.082 12.9 1.3 1.3 9.1 0.3 3.5 2 0 0 2 2 2 0 Flavinator of succinate dehydrogenase Sec15 PF04091.12 EGR27438.1 - 3.2e-16 59.7 3.0 3.7e-16 59.4 3.0 1.1 1 0 0 1 1 1 1 Exocyst complex subunit Sec15-like Imm26 PF15428.6 EGR27438.1 - 0.08 13.2 0.1 0.14 12.4 0.1 1.4 1 0 0 1 1 1 0 Immunity protein 26 His_Phos_2 PF00328.22 EGR27439.1 - 3.8e-20 72.6 6.7 1.7e-10 40.8 1.1 3.4 2 2 1 3 3 3 3 Histidine phosphatase superfamily (branch 2) Ank_2 PF12796.7 EGR27440.1 - 4.2e-21 75.3 0.3 2e-05 25.1 0.1 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EGR27440.1 - 4.4e-18 64.8 0.0 0.00089 19.6 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat EF-hand_1 PF00036.32 EGR27440.1 - 1.1e-16 59.1 10.1 4.8e-05 22.6 0.2 5.2 5 0 0 5 5 5 3 EF hand Ank_4 PF13637.6 EGR27440.1 - 1.9e-16 60.2 0.0 1.5e-05 25.4 0.0 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) EF-hand_5 PF13202.6 EGR27440.1 - 3.9e-15 54.6 4.9 0.00043 19.7 0.1 4.5 3 0 0 3 3 3 3 EF hand Ank_5 PF13857.6 EGR27440.1 - 2e-14 53.5 0.0 0.00018 21.7 0.0 4.2 2 1 3 5 5 5 3 Ankyrin repeats (many copies) EF-hand_6 PF13405.6 EGR27440.1 - 5.4e-14 50.9 7.0 0.00092 19.0 0.1 4.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EGR27440.1 - 2.3e-12 47.2 11.3 1.9e-08 34.6 0.4 4.9 6 1 1 7 7 6 3 EF-hand domain pair Ank_3 PF13606.6 EGR27440.1 - 9.2e-12 44.1 0.0 0.35 11.6 0.0 6.1 6 0 0 6 6 5 2 Ankyrin repeat EF-hand_8 PF13833.6 EGR27440.1 - 4.1e-08 32.9 7.5 1.3e-06 28.2 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain pair GutM PF06923.11 EGR27440.1 - 0.013 15.6 0.7 1.2 9.2 0.0 3.6 3 0 0 3 3 3 0 Glucitol operon activator protein (GutM) EF-hand_10 PF14788.6 EGR27440.1 - 0.02 14.7 8.0 0.21 11.5 0.3 3.6 3 0 0 3 3 3 0 EF hand EF-hand_2 PF09068.11 EGR27440.1 - 3.5 7.8 7.7 1.3 9.2 3.9 2.5 2 1 0 2 2 1 0 EF hand NYD-SP28_assoc PF14775.6 EGR27440.1 - 5.2 7.3 13.2 0.13 12.4 4.8 2.8 2 0 0 2 2 2 0 Sperm tail C-terminal domain Ephrin_rec_like PF07699.13 EGR27441.1 - 0.0015 18.2 2.2 0.0031 17.2 2.2 1.5 1 0 0 1 1 1 1 Putative ephrin-receptor like Sushi PF00084.20 EGR27441.1 - 0.69 10.6 4.9 0.31 11.6 1.2 2.3 2 0 0 2 2 2 0 Sushi repeat (SCR repeat) NCD3G PF07562.14 EGR27441.1 - 2.1 8.4 7.8 0.92 9.5 1.8 2.4 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR DUF667 PF05018.13 EGR27443.1 - 5.3e-80 267.5 10.3 1.6e-50 171.4 3.6 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF667) GHMP_kinases_N PF00288.26 EGR27444.1 - 0.00024 21.3 0.6 0.00044 20.4 0.6 1.4 1 0 0 1 1 1 1 GHMP kinases N terminal domain GalKase_gal_bdg PF10509.9 EGR27444.1 - 0.027 14.0 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 Galactokinase galactose-binding signature Ribosom_S30AE_C PF16321.5 EGR27445.1 - 0.046 13.4 1.1 6.9 6.5 0.0 2.4 2 0 0 2 2 2 0 Sigma 54 modulation/S30EA ribosomal protein C terminus Pkinase PF00069.25 EGR27446.1 - 3.6e-58 197.0 0.4 3.6e-58 197.0 0.4 2.3 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.29 EGR27446.1 - 3.2e-40 136.1 0.1 1.6e-16 60.2 0.0 3.8 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 EGR27446.1 - 2.2e-25 89.4 0.0 4.5e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27446.1 - 8.8e-06 25.2 0.0 1.9e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR27446.1 - 4.3e-05 22.5 0.0 4.3e-05 22.5 0.0 2.1 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 EGR27446.1 - 0.031 14.2 0.0 0.058 13.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family HsbA PF12296.8 EGR27446.1 - 0.075 13.5 0.9 0.25 11.8 0.9 1.8 1 0 0 1 1 1 0 Hydrophobic surface binding protein A Hepsin-SRCR PF09272.10 EGR27446.1 - 0.57 10.7 2.7 1.4 9.5 0.3 2.8 3 1 0 3 3 3 0 Hepsin, SRCR domain zf-CRD PF17979.1 EGR27446.1 - 0.65 10.1 5.0 2.8 8.0 5.0 2.2 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions Utp11 PF03998.13 EGR27446.1 - 8.1 6.3 13.8 1.9 8.3 7.1 2.2 2 0 0 2 2 2 0 Utp11 protein FYVE PF01363.21 EGR27447.1 - 1.5e-14 53.9 17.2 5e-14 52.2 17.2 2.0 1 0 0 1 1 1 1 FYVE zinc finger Cpn60_TCP1 PF00118.24 EGR27447.1 - 6.6e-10 38.2 3.0 8e-10 37.9 1.8 1.8 2 0 0 2 2 2 1 TCP-1/cpn60 chaperonin family zf-UBP PF02148.19 EGR27447.1 - 0.1 12.9 5.5 48 4.4 0.0 3.2 2 0 0 2 2 2 0 Zn-finger in ubiquitin-hydrolases and other protein Zip PF02535.22 EGR27447.1 - 0.54 9.4 2.6 0.82 8.8 2.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2052 PF09747.9 EGR27447.1 - 0.58 10.3 23.2 0.13 12.4 19.5 1.8 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) FAM176 PF14851.6 EGR27447.1 - 2.8 7.6 13.2 7.3 6.2 13.2 1.7 1 0 0 1 1 1 0 FAM176 family R_equi_Vir PF05526.11 EGR27447.1 - 8.3 6.2 6.2 1.7 8.5 0.1 2.3 2 0 0 2 2 2 0 Rhodococcus equi virulence-associated protein DUF1295 PF06966.12 EGR27450.1 - 0.0028 17.2 9.3 0.011 15.3 9.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 EGR27450.1 - 1.4 9.4 14.2 0.19 12.1 5.1 3.0 1 1 2 3 3 3 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DMAP1 PF05499.12 EGR27451.1 - 0.0038 17.1 18.9 0.0038 17.1 18.9 2.7 1 1 1 2 2 2 1 DNA methyltransferase 1-associated protein 1 (DMAP1) MORN PF02493.20 EGR27452.1 - 7.9e-42 138.7 55.1 9.8e-07 28.3 0.3 9.4 9 0 0 9 9 9 9 MORN repeat Tudor_2 PF18104.1 EGR27452.1 - 0.00081 19.0 4.4 2.5 7.8 0.1 4.0 3 0 0 3 3 3 3 Jumonji domain-containing protein 2A Tudor domain tRNA_lig_CPD PF08302.11 EGR27452.1 - 0.031 13.7 0.1 0.042 13.3 0.1 1.1 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain DUF523 PF04463.12 EGR27452.1 - 0.16 12.0 3.3 29 4.7 0.3 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF523) DUF3048_C PF17479.2 EGR27452.1 - 6.2 7.2 9.9 1.7 9.1 1.1 3.4 2 2 1 3 3 3 0 Protein of unknown function (DUF3048) C-terminal domain Late_protein_L2 PF00513.18 EGR27453.1 - 0.49 9.3 1.7 0.63 9.0 1.7 1.1 1 0 0 1 1 1 0 Late Protein L2 Rop PF01815.16 EGR27453.1 - 1.7 8.6 8.8 0.096 12.6 1.3 2.7 3 0 0 3 3 3 0 Rop protein zf-B_box PF00643.24 EGR27453.1 - 1.7 8.9 10.9 18 5.6 10.9 2.1 1 1 0 1 1 1 0 B-box zinc finger UCH_1 PF13423.6 EGR27454.1 - 1.3e-09 38.1 6.6 1.3e-09 38.1 6.6 2.0 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 EGR27454.1 - 1e-06 28.5 2.9 1e-06 28.5 2.9 2.2 1 1 1 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Exonuc_VII_L PF02601.15 EGR27454.1 - 0.52 9.8 10.0 0.53 9.8 10.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 EGR27454.1 - 1.8 7.4 12.6 2.1 7.2 12.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein ALMT PF11744.8 EGR27454.1 - 2.4 6.9 12.4 3.2 6.5 12.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter CLN3 PF02487.17 EGR27454.1 - 7.4 5.5 6.8 11 4.9 6.8 1.4 1 0 0 1 1 1 0 CLN3 protein Pkinase PF00069.25 EGR27456.1 - 8.8e-46 156.4 0.0 1.2e-45 156.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27456.1 - 1e-22 80.7 0.0 1.3e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 EGR27456.1 - 5.2e-05 22.5 0.0 8.5e-05 21.7 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 EGR27456.1 - 9.1e-05 21.9 0.0 0.00014 21.2 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR27456.1 - 0.00051 18.9 0.0 0.00066 18.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase HIF-1 PF11413.8 EGR27456.1 - 0.12 11.8 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 Hypoxia-inducible factor-1 Methyltransf_28 PF02636.17 EGR27457.1 - 5.5e-31 108.1 1.6 7.9e-31 107.6 1.6 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 EGR27457.1 - 1.6e-05 25.6 1.7 2.2e-05 25.1 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGR27457.1 - 3.4e-05 23.7 0.0 0.00039 20.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGR27457.1 - 0.04 14.6 0.0 0.1 13.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Dna2 PF08696.11 EGR27457.1 - 0.13 12.1 5.9 0.055 13.3 0.9 2.2 2 0 0 2 2 2 0 DNA replication factor Dna2 cNMP_binding PF00027.29 EGR27458.1 - 3.7e-12 46.1 0.0 6.6e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGR27458.1 - 0.009 16.0 2.2 0.015 15.3 2.2 1.4 1 0 0 1 1 1 1 Ion channel tRNA_deacylase PF04414.12 EGR27458.1 - 0.088 12.3 0.6 0.18 11.3 0.6 1.6 1 0 0 1 1 1 0 D-aminoacyl-tRNA deacylase Calici_MSP PF05752.11 EGR27458.1 - 0.23 11.3 1.0 0.74 9.6 1.0 1.8 1 0 0 1 1 1 0 Calicivirus minor structural protein DUF3586 PF12131.8 EGR27458.1 - 1.6 9.0 3.9 1 9.6 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3586) BK_channel_a PF03493.18 EGR27459.1 - 2.1e-30 104.8 1.3 1.4e-27 95.7 0.0 4.0 4 0 0 4 4 4 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 EGR27459.1 - 1e-13 51.0 1.1 1e-13 51.0 1.1 1.9 2 0 0 2 2 2 1 Ion channel TrkA_N PF02254.18 EGR27459.1 - 7.6e-08 32.6 0.0 0.0081 16.4 0.0 2.4 2 0 0 2 2 2 2 TrkA-N domain Castor_Poll_mid PF06241.12 EGR27459.1 - 0.019 14.9 0.1 0.31 11.0 0.0 2.7 2 0 0 2 2 2 0 Castor and Pollux, part of voltage-gated ion channel Ion_trans PF00520.31 EGR27459.1 - 0.34 10.1 16.6 0.6 9.3 2.2 2.4 1 1 1 2 2 2 0 Ion transport protein TPR_12 PF13424.6 EGR27460.1 - 0.15 12.3 1.8 2.6 8.4 0.1 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGR27460.1 - 0.22 11.4 5.1 0.19 11.6 2.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat E3_UFM1_ligase PF09743.9 EGR27461.1 - 5.4e-67 226.3 30.5 5.4e-67 226.3 30.5 3.5 2 2 0 3 3 3 1 E3 UFM1-protein ligase 1 Cullin_Nedd8 PF10557.9 EGR27461.1 - 0.027 14.5 0.2 0.027 14.5 0.2 5.3 6 1 0 6 6 6 0 Cullin protein neddylation domain Rrf2 PF02082.20 EGR27461.1 - 0.83 10.0 2.9 22 5.5 0.0 3.8 4 0 0 4 4 4 0 Transcriptional regulator Zip PF02535.22 EGR27461.1 - 8.7 5.4 5.6 18 4.4 5.6 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Ras PF00071.22 EGR27462.1 - 2e-41 141.3 0.1 2.4e-41 141.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR27462.1 - 1.2e-34 119.1 0.0 1.7e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR27462.1 - 3e-14 52.8 0.0 3.4e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR27462.1 - 8.1e-06 25.9 0.0 1.1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGR27462.1 - 0.00017 21.1 0.0 0.00021 20.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGR27462.1 - 0.00044 19.8 0.0 0.053 13.0 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 EGR27462.1 - 0.00083 18.9 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region SRPRB PF09439.10 EGR27462.1 - 0.0016 17.9 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 EGR27462.1 - 0.011 15.5 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein TniB PF05621.11 EGR27462.1 - 0.02 14.3 0.0 0.041 13.3 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein PI3_PI4_kinase PF00454.27 EGR27463.1 - 2.9e-27 96.1 6.0 4.6e-27 95.4 0.8 2.6 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGR27463.1 - 0.0013 18.1 4.3 0.003 17.0 4.3 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pkinase PF00069.25 EGR27464.1 - 2.4e-05 23.8 0.0 3.1e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27464.1 - 0.0013 18.1 0.1 0.0016 17.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase TEX12 PF15219.6 EGR27464.1 - 0.032 14.6 0.1 0.053 13.8 0.1 1.4 1 0 0 1 1 1 0 Testis-expressed 12 FTA2 PF13095.6 EGR27464.1 - 0.034 13.8 0.1 0.039 13.6 0.1 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EGR27464.1 - 0.035 13.1 0.3 0.039 12.9 0.3 1.0 1 0 0 1 1 1 0 Haspin like kinase domain Ribosomal_L14e PF01929.17 EGR27465.1 - 1.4e-23 83.2 7.4 1.4e-23 83.2 7.4 2.0 1 1 1 2 2 2 1 Ribosomal protein L14 KOW PF00467.29 EGR27465.1 - 0.0014 18.5 2.0 0.0049 16.8 2.0 2.0 1 0 0 1 1 1 1 KOW motif Abhydrolase_1 PF00561.20 EGR27466.1 - 4.3e-12 46.2 1.1 5.7e-11 42.6 0.3 2.5 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGR27466.1 - 4.5e-10 39.2 0.0 9.5e-10 38.1 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGR27466.1 - 0.016 14.7 0.2 0.23 10.9 0.0 2.4 2 0 0 2 2 2 0 Prolyl oligopeptidase family HEAT PF02985.22 EGR27467.1 - 0.099 13.0 0.0 0.61 10.5 0.0 2.5 1 0 0 1 1 1 0 HEAT repeat Ribosomal_L14e PF01929.17 EGR27468.1 - 1.2e-23 83.3 8.1 2e-23 82.7 8.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 KOW PF00467.29 EGR27468.1 - 0.0014 18.5 2.0 0.0046 16.9 2.0 2.0 1 0 0 1 1 1 1 KOW motif SK_channel PF03530.14 EGR27469.1 - 0.00033 20.6 0.7 0.00033 20.6 0.7 1.8 2 0 0 2 2 2 1 Calcium-activated SK potassium channel DUF5301 PF17225.3 EGR27470.1 - 0.017 15.5 0.9 0.042 14.3 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5300) Ephrin_rec_like PF07699.13 EGR27470.1 - 1.4 8.8 7.1 7.8 6.3 2.3 2.6 2 0 0 2 2 2 0 Putative ephrin-receptor like UPF0061 PF02696.14 EGR27471.1 - 3.4e-121 405.3 0.3 4.3e-121 404.9 0.3 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family MetOD1 PF18546.1 EGR27471.1 - 0.41 10.6 3.2 0.22 11.5 0.6 1.9 2 0 0 2 2 2 0 Metanogen output domain 1 Yqai PF09466.10 EGR27471.1 - 0.55 10.6 3.7 0.61 10.4 0.4 2.7 3 0 0 3 3 3 0 Hypothetical protein Yqai Orthopox_B11R PF07033.11 EGR27471.1 - 7.5 6.4 8.1 5.2 6.9 2.5 3.0 3 0 0 3 3 3 0 Orthopoxvirus B11R protein DUF2052 PF09747.9 EGR27472.1 - 9.1e-16 58.6 16.6 1.1e-15 58.3 16.6 1.0 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) TTL PF03133.15 EGR27473.1 - 2.3e-53 181.2 25.1 2.3e-53 181.2 25.1 3.8 3 1 1 4 4 4 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR27473.1 - 5.6e-06 25.8 6.3 0.00035 19.9 0.0 4.1 4 0 0 4 4 4 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR27473.1 - 0.0012 18.2 4.1 0.011 15.1 0.0 3.0 2 1 0 2 2 2 1 Sugar-transfer associated ATP-grasp MMTV_SAg PF01054.17 EGR27473.1 - 0.012 15.2 0.7 0.012 15.2 0.7 2.7 3 0 0 3 3 3 0 Mouse mammary tumour virus superantigen Dala_Dala_lig_C PF07478.13 EGR27473.1 - 0.29 10.7 0.0 0.29 10.7 0.0 3.5 3 1 0 3 3 3 0 D-ala D-ala ligase C-terminus Peptidase_C54 PF03416.19 EGR27474.1 - 2.3e-36 125.7 4.6 3.7e-36 125.0 4.6 1.3 1 0 0 1 1 1 1 Peptidase family C54 zf-AD PF07776.15 EGR27474.1 - 3.8 7.8 7.6 1.4 9.2 3.4 2.6 3 0 0 3 3 3 0 Zinc-finger associated domain (zf-AD) NAD_synthase PF02540.17 EGR27476.1 - 3.9e-25 88.4 0.1 9.8e-25 87.1 0.1 1.6 1 1 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.22 EGR27476.1 - 1.7e-19 70.2 0.0 7.6e-19 68.1 0.0 1.9 1 1 0 1 1 1 1 Carbon-nitrogen hydrolase UQ_con PF00179.26 EGR27476.1 - 4.3e-13 49.1 0.4 8.3e-13 48.2 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SHR3_chaperone PF08229.11 EGR27476.1 - 0.04 12.9 0.0 0.081 11.9 0.0 1.4 1 0 0 1 1 1 0 ER membrane protein SH3 DUF21 PF01595.20 EGR27478.1 - 5.6e-28 97.8 3.3 9.8e-28 97.0 2.5 1.8 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain Ras PF00071.22 EGR27478.1 - 3e-18 65.9 1.1 9.3e-18 64.3 1.1 1.8 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR27478.1 - 9.7e-11 41.9 0.2 9.7e-11 41.9 0.2 2.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR27478.1 - 2.8e-05 23.6 0.6 0.00025 20.5 0.0 2.5 2 0 0 2 2 2 1 ADP-ribosylation factor family CBS PF00571.28 EGR27478.1 - 0.00023 21.6 0.0 0.42 11.1 0.0 2.8 2 0 0 2 2 2 2 CBS domain Zip PF02535.22 EGR27478.1 - 0.0037 16.5 0.1 0.0065 15.7 0.1 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter Serinc PF03348.15 EGR27478.1 - 0.0055 15.7 1.4 0.0099 14.9 1.4 1.3 1 0 0 1 1 1 1 Serine incorporator (Serinc) GTP_EFTU PF00009.27 EGR27478.1 - 0.0067 16.0 0.0 0.021 14.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGR27478.1 - 0.014 15.5 0.0 0.06 13.4 0.0 2.2 1 0 0 1 1 1 0 50S ribosome-binding GTPase DivIC PF04977.15 EGR27478.1 - 1.1 9.0 14.3 0.56 10.0 4.8 3.4 3 0 0 3 3 3 0 Septum formation initiator WBP-1 PF11669.8 EGR27478.1 - 2.3 8.9 4.8 10 6.8 0.0 3.6 3 1 0 3 3 3 0 WW domain-binding protein 1 MTS PF05175.14 EGR27479.1 - 2.4e-07 30.4 0.0 3.7e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGR27479.1 - 1.8e-05 24.3 0.1 2.5e-05 23.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EGR27479.1 - 0.00035 21.2 0.0 0.0006 20.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain N6-adenineMlase PF10237.9 EGR27479.1 - 0.0017 18.2 1.0 0.003 17.4 0.9 1.4 1 1 0 1 1 1 1 Probable N6-adenine methyltransferase Methyltransf_11 PF08241.12 EGR27479.1 - 0.0029 18.2 0.0 0.0049 17.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGR27479.1 - 0.0029 17.3 0.0 0.0058 16.3 0.0 1.5 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_31 PF13847.6 EGR27479.1 - 0.011 15.5 0.1 0.016 15.0 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain N6_Mtase PF02384.16 EGR27479.1 - 0.015 14.6 0.1 0.025 13.8 0.1 1.4 1 1 0 1 1 1 0 N-6 DNA Methylase Methyltransf_9 PF08003.11 EGR27479.1 - 0.024 13.5 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.6 EGR27479.1 - 0.07 13.0 0.0 0.092 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 EGR27479.1 - 0.15 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain CHCH PF06747.13 EGR27480.1 - 0.00012 22.2 6.6 0.00018 21.5 6.6 1.3 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 EGR27480.1 - 0.019 15.0 3.0 2.9 8.0 0.3 2.2 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like CYSTM PF12734.7 EGR27480.1 - 0.52 10.7 6.8 1.1 9.7 0.5 2.3 2 0 0 2 2 2 0 Cysteine-rich TM module stress tolerance Sin3_corepress PF08295.12 EGR27481.1 - 1.3e-25 89.3 1.7 1.3e-25 89.3 1.7 2.6 3 0 0 3 3 3 1 Sin3 family co-repressor CKS PF01111.19 EGR27482.1 - 2.2e-38 130.4 2.0 2.5e-38 130.2 2.0 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF4338 PF14236.6 EGR27482.1 - 0.085 12.1 0.0 0.1 11.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4338) PK PF00224.21 EGR27483.1 - 8.2e-41 140.0 0.0 1.1e-40 139.7 0.0 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EGR27483.1 - 0.068 13.4 0.3 0.19 12.0 0.2 1.8 2 0 0 2 2 2 0 Pyruvate kinase, alpha/beta domain PGK PF00162.19 EGR27484.1 - 0.014 14.4 1.0 0.014 14.4 1.0 1.4 1 1 0 1 1 1 0 Phosphoglycerate kinase DUF2520 PF10728.9 EGR27484.1 - 0.12 12.1 0.1 0.41 10.4 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2520) Ribonuc_red_lgC PF02867.15 EGR27484.1 - 0.37 9.3 6.5 0.1 11.1 3.3 1.7 1 1 0 1 1 1 0 Ribonucleotide reductase, barrel domain SF-assemblin PF06705.11 EGR27484.1 - 7.6 5.8 35.2 13 5.1 13.4 2.5 1 1 0 1 1 1 0 SF-assemblin/beta giardin Anoctamin PF04547.12 EGR27485.1 - 0.041 12.7 10.5 0.058 12.2 10.5 1.2 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF1850 PF08905.11 EGR27485.1 - 0.046 14.0 0.0 0.087 13.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1850) RSN1_7TM PF02714.15 EGR27485.1 - 1.5 8.1 17.2 9 5.5 13.2 2.9 1 1 0 1 1 1 0 Calcium-dependent channel, 7TM region, putative phosphate HEAT PF02985.22 EGR27486.1 - 5.2e-11 41.8 0.9 0.012 15.8 0.0 5.9 7 0 0 7 7 7 3 HEAT repeat HEAT_EZ PF13513.6 EGR27486.1 - 1.6e-09 38.0 0.0 0.00058 20.3 0.0 4.1 4 0 0 4 4 4 2 HEAT-like repeat IBN_N PF03810.19 EGR27486.1 - 0.00036 20.4 1.2 0.00036 20.4 1.2 5.2 6 0 0 6 6 6 1 Importin-beta N-terminal domain DnaJ-X PF14308.6 EGR27486.1 - 0.043 13.3 1.1 0.22 10.9 0.1 2.6 2 0 0 2 2 2 0 X-domain of DnaJ-containing TIP120 PF08623.10 EGR27486.1 - 0.15 11.8 10.0 11 5.7 0.0 4.8 4 1 1 5 5 5 0 TATA-binding protein interacting (TIP20) CelTOS PF18659.1 EGR27486.1 - 0.15 12.5 0.2 0.15 12.5 0.2 4.5 4 2 0 4 4 4 0 Cell-traversal protein for ookinetes and sporozoites EF-hand_1 PF00036.32 EGR27487.1 - 0.00015 21.0 0.0 0.07 12.7 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGR27487.1 - 0.00027 21.3 0.1 0.00041 20.7 0.1 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGR27487.1 - 0.00065 19.4 0.0 0.063 13.2 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain BAH PF01426.18 EGR27488.1 - 9.1e-10 38.5 2.1 1.2e-09 38.0 2.1 1.2 1 0 0 1 1 1 1 BAH domain CNRIP1 PF15043.6 EGR27488.1 - 0.0076 15.8 1.8 0.013 15.1 0.2 2.1 2 1 1 3 3 3 1 CB1 cannabinoid receptor-interacting protein 1 Aminotran_5 PF00266.19 EGR27489.1 - 1.8e-26 93.0 0.0 2.2e-26 92.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V rhaM PF05336.13 EGR27490.1 - 2.6e-26 91.8 2.6 3.2e-26 91.5 2.6 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase Myb_DNA-bind_6 PF13921.6 EGR27490.1 - 0.11 12.7 3.9 0.31 11.3 0.0 2.5 2 1 0 2 2 2 0 Myb-like DNA-binding domain Aldo_ket_red PF00248.21 EGR27491.1 - 4.3e-20 72.1 0.0 5.3e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family BBP2 PF07642.11 EGR27491.1 - 0.025 13.7 0.5 0.044 12.9 0.5 1.6 1 1 0 1 1 1 0 Putative beta-barrel porin-2, OmpL-like. bbp2 Vps39_2 PF10367.9 EGR27493.1 - 4.5e-22 78.6 2.1 4.5e-22 78.6 2.1 2.8 3 0 0 3 3 3 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 EGR27493.1 - 1.1e-05 25.3 7.1 1.1e-05 25.3 7.1 3.5 3 1 0 3 3 3 1 Region in Clathrin and VPS DUF349 PF03993.12 EGR27493.1 - 0.023 15.0 0.2 0.3 11.4 0.0 3.1 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) DUF561 PF04481.12 EGR27493.1 - 0.17 11.0 2.2 0.34 10.0 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF561) Phage_int_SAM_4 PF13495.6 EGR27494.1 - 0.01 16.3 2.5 0.49 10.9 0.1 2.8 2 1 1 3 3 3 0 Phage integrase, N-terminal SAM-like domain LuxE PF04443.12 EGR27495.1 - 0.06 12.4 0.5 0.1 11.6 0.5 1.3 1 0 0 1 1 1 0 Acyl-protein synthetase, LuxE E1-E2_ATPase PF00122.20 EGR27496.1 - 3.7e-39 134.1 0.1 3.7e-39 134.1 0.1 2.6 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGR27496.1 - 1.1e-29 103.5 10.9 5.5e-20 71.8 0.0 3.4 2 1 1 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGR27496.1 - 5.8e-20 72.5 0.0 4.3e-11 43.5 0.0 2.7 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGR27496.1 - 1.7e-14 53.3 0.0 3.8e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGR27496.1 - 2e-11 43.8 0.0 4.6e-11 42.6 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) DUF2207 PF09972.9 EGR27496.1 - 1.9 7.2 8.9 2.8 6.6 0.1 3.3 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Hydrolase_3 PF08282.12 EGR27496.1 - 5.1 6.8 16.3 0.45 10.2 1.2 3.8 3 1 0 4 4 4 0 haloacid dehalogenase-like hydrolase CS PF04969.16 EGR27497.1 - 8.3e-05 23.5 0.3 0.0002 22.3 0.3 1.7 1 0 0 1 1 1 1 CS domain S-AdoMet_synt_C PF02773.16 EGR27498.1 - 1.2e-60 203.5 0.0 2.3e-60 202.6 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EGR27498.1 - 6.7e-39 132.8 0.1 1.4e-38 131.8 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EGR27498.1 - 5.3e-35 120.1 1.4 1.3e-34 118.8 0.3 2.0 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, N-terminal domain AdoMet_Synthase PF01941.19 EGR27498.1 - 0.011 14.5 0.3 1.4 7.6 0.1 2.4 2 0 0 2 2 2 0 S-adenosylmethionine synthetase (AdoMet synthetase) Anoctamin PF04547.12 EGR27499.1 - 9e-90 301.7 26.3 1.9e-89 300.6 26.3 1.5 1 0 0 1 1 1 1 Calcium-activated chloride channel zf-B_box PF00643.24 EGR27499.1 - 0.037 14.2 8.9 0.11 12.6 8.9 1.8 1 0 0 1 1 1 0 B-box zinc finger DUF2284 PF10050.9 EGR27499.1 - 0.096 12.4 7.8 0.073 12.8 4.8 2.4 1 1 1 2 2 2 0 Predicted metal-binding protein (DUF2284) zf-UBR PF02207.20 EGR27499.1 - 1.4 9.1 10.1 0.92 9.7 6.1 2.7 3 0 0 3 3 3 0 Putative zinc finger in N-recognin (UBR box) ZZ PF00569.17 EGR27499.1 - 7.1 6.5 15.6 0.43 10.4 9.9 1.9 2 0 0 2 2 2 0 Zinc finger, ZZ type Ank_2 PF12796.7 EGR27500.1 - 8e-19 68.0 6.0 5.3e-05 23.7 0.1 4.4 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGR27500.1 - 1.2e-14 54.5 6.6 0.00011 22.7 0.2 5.4 4 1 2 6 6 6 2 Ankyrin repeats (many copies) Ank PF00023.30 EGR27500.1 - 3.8e-13 49.2 0.1 1.7e-05 25.0 0.0 5.4 5 0 0 5 5 5 2 Ankyrin repeat Ank_3 PF13606.6 EGR27500.1 - 3.8e-12 45.3 1.5 0.00051 20.3 0.0 5.5 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EGR27500.1 - 4.7e-11 42.7 1.6 1.6e-05 25.1 0.1 4.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Prefoldin PF02996.17 EGR27501.1 - 5.8e-28 97.2 2.8 5.8e-28 97.2 2.8 2.0 1 1 1 2 2 2 2 Prefoldin subunit Prefoldin_2 PF01920.20 EGR27501.1 - 0.003 17.5 8.7 0.035 14.0 0.1 2.5 2 1 0 2 2 2 2 Prefoldin subunit HSBP1 PF06825.12 EGR27501.1 - 0.014 15.3 2.8 0.03 14.2 2.8 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 RecG_N PF17190.4 EGR27501.1 - 0.051 14.3 2.8 0.051 14.3 2.8 2.2 2 1 0 2 2 2 0 RecG N-terminal helical domain DUF745 PF05335.13 EGR27501.1 - 2.5 7.8 6.8 1.5 8.5 1.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) CHORD PF04968.12 EGR27502.1 - 1.8e-05 25.4 42.5 0.00021 21.9 5.8 5.5 4 2 1 5 5 5 3 CHORD BTK PF00779.19 EGR27502.1 - 0.0017 18.1 31.7 0.0019 18.0 2.5 4.9 4 0 0 4 4 4 3 BTK motif Pkinase PF00069.25 EGR27503.1 - 1.6e-59 201.4 0.4 2e-59 201.1 0.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27503.1 - 2.6e-26 92.5 0.1 3.2e-26 92.2 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR27503.1 - 4.3e-06 25.8 0.0 5.2e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR27503.1 - 2.7e-05 23.6 0.0 4e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGR27503.1 - 0.00085 18.7 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGR27503.1 - 0.041 13.8 0.0 0.068 13.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EGR27503.1 - 0.047 13.3 0.3 0.23 11.1 0.2 2.0 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 EGR27504.1 - 2.1e-56 191.2 0.4 4.2e-56 190.2 0.4 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27504.1 - 5.5e-39 134.0 0.1 1.1e-38 133.0 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EGR27504.1 - 1.6e-22 79.7 13.2 2.9e-12 46.9 4.9 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR27504.1 - 3.8e-19 66.9 11.5 5.4e-06 25.9 0.3 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 EGR27504.1 - 4.5e-19 66.5 14.0 2.6e-06 26.6 1.5 4.7 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGR27504.1 - 2e-09 37.1 14.3 1e-05 25.3 2.8 4.5 4 2 2 6 6 6 2 EF-hand domain pair Pkinase_fungal PF17667.1 EGR27504.1 - 1.1e-07 31.0 0.0 2.1e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RST PF12174.8 EGR27504.1 - 1.4e-07 31.3 0.4 0.007 16.3 0.2 2.9 2 0 0 2 2 2 2 RCD1-SRO-TAF4 (RST) plant domain EF-hand_5 PF13202.6 EGR27504.1 - 1.4e-06 27.5 10.5 0.0005 19.4 0.8 4.3 4 0 0 4 4 4 2 EF hand p25-alpha PF05517.12 EGR27504.1 - 3.8e-06 27.1 12.1 0.0054 16.9 2.0 3.5 3 1 0 3 3 2 2 p25-alpha SPARC_Ca_bdg PF10591.9 EGR27504.1 - 0.0023 18.2 13.6 0.017 15.4 2.4 3.2 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 EGR27504.1 - 0.018 15.0 12.0 3 7.7 0.1 4.4 2 2 2 4 4 4 0 Caleosin related protein APH PF01636.23 EGR27504.1 - 0.023 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ThrE PF06738.12 EGR27504.1 - 0.13 11.6 0.0 1.8 7.9 0.0 2.2 2 0 0 2 2 2 0 Putative threonine/serine exporter EF-hand_4 PF12763.7 EGR27504.1 - 0.15 12.0 7.8 9.1 6.3 0.2 3.6 2 2 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EGR27504.1 - 0.39 10.6 9.4 2.2 8.2 0.4 4.2 3 1 1 4 4 4 0 EF hand EF-hand_14 PF17959.1 EGR27504.1 - 0.58 10.5 4.5 23 5.4 0.1 3.7 3 0 0 3 3 3 0 EF-hand domain Ephrin_rec_like PF07699.13 EGR27505.1 - 1.5 8.6 11.4 0.1 12.4 4.7 2.5 2 1 0 2 2 2 0 Putative ephrin-receptor like Yippee-Mis18 PF03226.14 EGR27506.1 - 1.9e-15 57.0 0.3 2.2e-15 56.7 0.3 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF2039 PF10217.9 EGR27506.1 - 0.023 15.0 0.5 0.035 14.4 0.1 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) RIG-I_C-RD PF11648.8 EGR27506.1 - 0.054 13.7 0.4 0.076 13.3 0.4 1.4 1 1 0 1 1 1 0 C-terminal domain of RIG-I Pkinase PF00069.25 EGR27507.1 - 1.5e-76 257.3 7.1 1.1e-74 251.2 2.5 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27507.1 - 7.6e-38 130.3 0.3 7.6e-38 130.3 0.3 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_1 PF00036.32 EGR27507.1 - 2.9e-27 92.2 6.7 1.2e-06 27.7 0.5 4.9 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGR27507.1 - 8.5e-24 81.4 5.5 3e-06 26.7 0.3 4.9 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EGR27507.1 - 1.3e-23 83.2 4.4 2.7e-12 46.9 0.8 3.2 3 0 0 3 3 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGR27507.1 - 8.8e-23 78.7 8.5 0.00013 21.3 0.6 4.7 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGR27507.1 - 9.7e-18 63.8 4.7 5.6e-09 35.7 0.3 4.8 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGR27507.1 - 3.7e-11 43.3 4.3 8.8e-06 26.0 0.3 3.0 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.14 EGR27507.1 - 3.7e-07 29.7 0.3 7.6e-07 28.7 0.3 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGR27507.1 - 1.4e-06 27.8 0.1 2.7e-06 26.9 0.1 1.5 1 0 0 1 1 1 1 Kinase-like EF-hand_4 PF12763.7 EGR27507.1 - 4.5e-05 23.3 4.3 0.13 12.2 1.1 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand APH PF01636.23 EGR27507.1 - 6.4e-05 23.0 0.0 0.0001 22.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGR27507.1 - 0.005 16.5 1.0 0.019 14.6 1.0 2.1 1 1 0 1 1 1 1 Choline/ethanolamine kinase Ribosomal_S26e PF01283.19 EGR27507.1 - 0.016 15.7 0.5 0.81 10.2 0.2 2.5 2 0 0 2 2 2 0 Ribosomal protein S26e UPF0004 PF00919.20 EGR27507.1 - 0.063 13.3 1.4 0.14 12.2 0.2 2.2 2 0 0 2 2 2 0 Uncharacterized protein family UPF0004 Spore_YhaL PF14147.6 EGR27507.1 - 3.6 7.4 4.9 37 4.1 0.0 4.0 4 0 0 4 4 4 0 Sporulation protein YhaL GDC-P PF02347.16 EGR27508.1 - 7.6e-173 575.3 0.0 1.1e-158 528.6 0.0 2.3 2 0 0 2 2 2 2 Glycine cleavage system P-protein Beta_elim_lyase PF01212.21 EGR27508.1 - 0.015 14.6 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase ABC_tran PF00005.27 EGR27509.1 - 4.9e-32 111.3 0.2 1.8e-31 109.5 0.0 2.0 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 EGR27509.1 - 4.2e-13 49.6 6.8 6.3e-13 49.0 6.8 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EGR27509.1 - 2.8e-07 30.2 0.0 6e-07 29.1 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGR27509.1 - 3.4e-05 23.8 0.0 0.0029 17.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGR27509.1 - 0.001 19.0 0.0 0.0023 17.8 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase NB-ARC PF00931.22 EGR27509.1 - 0.0047 16.1 0.8 0.013 14.7 0.8 1.8 1 1 0 1 1 1 1 NB-ARC domain Peptidase_C47 PF05543.13 EGR27509.1 - 0.016 14.8 0.7 0.037 13.6 0.7 1.6 1 0 0 1 1 1 0 Staphopain peptidase C47 AAA_22 PF13401.6 EGR27509.1 - 0.023 15.0 0.0 0.064 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain ABC_ATPase PF09818.9 EGR27509.1 - 0.044 12.6 0.8 0.53 9.0 0.0 2.5 3 0 0 3 3 3 0 Predicted ATPase of the ABC class UB2H PF14814.6 EGR27509.1 - 0.052 13.6 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Bifunctional transglycosylase second domain IstB_IS21 PF01695.17 EGR27509.1 - 0.066 12.9 0.3 12 5.6 0.1 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_18 PF13238.6 EGR27509.1 - 0.1 13.1 0.3 12 6.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 EGR27509.1 - 0.1 12.7 0.7 0.72 10.0 0.7 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EGR27509.1 - 0.2 12.0 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain EF-hand_8 PF13833.6 EGR27510.1 - 1e-07 31.7 0.7 6.7e-06 25.9 0.2 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGR27510.1 - 0.00043 19.6 3.5 0.36 10.5 0.3 4.1 3 1 1 4 4 4 2 EF hand EF-hand_7 PF13499.6 EGR27510.1 - 0.00064 20.1 3.9 0.015 15.7 0.3 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR27510.1 - 0.039 13.9 7.3 0.36 10.9 0.0 3.8 4 1 0 4 4 4 0 EF-hand domain zf-LITAF-like PF10601.9 EGR27512.1 - 8.2e-11 42.0 12.3 1.2e-10 41.5 12.3 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Haem_bd PF14376.6 EGR27512.1 - 0.038 13.9 0.2 0.051 13.5 0.2 1.2 1 0 0 1 1 1 0 Haem-binding domain Desulfoferrod_N PF06397.12 EGR27512.1 - 1.1 8.9 11.6 0.99 9.1 0.2 2.9 2 1 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF1765 PF08578.10 EGR27513.1 - 9.8e-24 84.2 12.8 9.8e-24 84.2 12.8 4.3 3 1 0 3 3 3 1 Protein of unknown function (DUF1765) C2 PF00168.30 EGR27513.1 - 0.0006 20.1 0.0 0.0026 18.0 0.0 2.1 1 0 0 1 1 1 1 C2 domain Adaptin_N PF01602.20 EGR27514.1 - 1.3e-102 344.1 27.4 1.3e-102 344.1 27.4 1.4 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 EGR27514.1 - 4.6e-46 156.8 17.4 2.9e-45 154.2 4.2 3.9 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGR27514.1 - 5.7e-07 29.8 0.4 0.012 16.0 0.0 4.9 5 2 0 5 5 5 1 HEAT repeats HEAT PF02985.22 EGR27514.1 - 0.00014 21.8 1.2 0.03 14.6 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat T3SchapCesA PF11439.8 EGR27514.1 - 0.28 11.4 3.9 8 6.7 0.4 3.0 2 0 0 2 2 2 0 Type III secretion system filament chaperone CesA ERGIC_N PF13850.6 EGR27517.1 - 0.00018 21.8 2.2 0.0011 19.3 0.1 3.2 3 0 0 3 3 3 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF4064 PF13273.6 EGR27517.1 - 0.026 14.8 0.4 0.78 10.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Exonuc_VII_L PF02601.15 EGR27518.1 - 0.0078 15.8 2.1 0.009 15.6 2.1 1.1 1 0 0 1 1 1 1 Exonuclease VII, large subunit LMBR1 PF04791.16 EGR27518.1 - 0.28 10.1 3.6 0.44 9.4 3.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein CREPT PF16566.5 EGR27518.1 - 0.75 10.0 10.1 1.6 8.9 9.9 1.6 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF1910 PF08928.10 EGR27518.1 - 1.3 9.1 8.2 2.4 8.2 8.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) MFS_1 PF07690.16 EGR27519.1 - 1.1e-16 60.7 23.9 4.5e-11 42.3 14.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily EMP70 PF02990.16 EGR27520.1 - 2.7e-131 438.8 41.7 4.1e-131 438.2 41.7 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 ETRAMP PF09716.10 EGR27520.1 - 0.92 9.6 0.0 0.92 9.6 0.0 3.8 4 1 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) RRM_1 PF00076.22 EGR27521.1 - 5.4e-15 55.0 0.8 5e-06 26.3 0.0 3.3 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EGR27521.1 - 1.7 9.8 3.7 0.58 11.3 0.2 2.0 3 0 0 3 3 3 0 linker between RRM2 and RRM3 domains in RBM39 protein DUF2956 PF11169.8 EGR27521.1 - 5.8 7.2 12.3 0.89 9.8 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Ras PF00071.22 EGR27525.1 - 1.3e-53 181.0 5.1 1.7e-53 180.6 5.1 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR27525.1 - 5e-28 97.7 1.1 5e-28 97.7 1.1 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR27525.1 - 1.2e-11 44.4 1.5 1.8e-11 43.8 1.5 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR27525.1 - 2e-06 27.9 0.2 4.1e-06 26.9 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGR27525.1 - 5.9e-05 22.7 1.6 0.0002 21.0 1.6 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGR27525.1 - 9.6e-05 22.0 1.1 0.00022 20.8 0.6 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGR27525.1 - 0.0001 22.3 0.7 0.0016 18.4 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EGR27525.1 - 0.00018 21.0 1.2 0.00024 20.6 1.2 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EGR27525.1 - 0.012 15.1 0.2 0.026 14.0 0.1 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region TniB PF05621.11 EGR27525.1 - 0.013 15.0 0.0 0.023 14.1 0.0 1.7 1 1 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 EGR27525.1 - 0.019 15.4 0.0 0.036 14.4 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGR27525.1 - 0.047 14.0 0.1 0.19 12.0 0.1 2.0 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGR27525.1 - 0.088 12.5 0.7 0.42 10.3 0.3 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein Flavokinase PF01687.17 EGR27525.1 - 0.12 12.7 1.4 0.34 11.2 0.2 2.0 1 1 0 2 2 2 0 Riboflavin kinase ABC_tran PF00005.27 EGR27525.1 - 0.19 12.2 1.5 0.34 11.4 1.5 1.7 1 1 0 1 1 1 0 ABC transporter Thioredoxin PF00085.20 EGR27526.1 - 4.3e-16 58.8 0.7 9e-16 57.7 0.1 1.9 2 0 0 2 2 2 1 Thioredoxin Thioredoxin_6 PF13848.6 EGR27526.1 - 1.9e-10 41.0 15.1 6.1e-09 36.1 6.7 2.3 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGR27526.1 - 0.022 15.1 4.8 0.072 13.4 0.0 3.3 2 1 2 4 4 4 0 Thioredoxin-like Thioredoxin_7 PF13899.6 EGR27526.1 - 0.027 14.6 0.0 0.083 13.1 0.0 1.8 1 0 0 1 1 1 0 Thioredoxin-like Toprim_Crpt PF13342.6 EGR27526.1 - 0.18 11.8 3.3 1.3 9.0 0.1 3.4 3 0 0 3 3 3 0 C-terminal repeat of topoisomerase Thioredoxin_2 PF13098.6 EGR27526.1 - 0.65 10.5 3.5 0.94 10.0 0.1 2.8 2 2 1 3 3 3 0 Thioredoxin-like domain EF-hand_7 PF13499.6 EGR27527.1 - 2.6e-11 43.8 6.4 2.4e-10 40.7 0.5 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR27527.1 - 7.3e-09 34.9 2.7 0.0059 16.4 0.0 4.0 3 1 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EGR27527.1 - 1.6e-08 33.5 8.9 9.3e-06 24.8 0.7 3.3 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 EGR27527.1 - 2e-06 27.0 2.1 0.024 14.1 0.0 2.8 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGR27527.1 - 0.14 12.0 6.9 0.16 11.8 0.5 3.6 3 1 1 4 4 4 0 EF-hand domain pair DUF1456 PF07308.13 EGR27527.1 - 0.17 12.3 5.3 0.18 12.2 0.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) FAM176 PF14851.6 EGR27528.1 - 0.69 9.6 12.8 0.91 9.2 12.8 1.2 1 0 0 1 1 1 0 FAM176 family Pro_isomerase PF00160.21 EGR27529.1 - 4.6e-48 163.5 0.1 5.7e-48 163.2 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD LRR_6 PF13516.6 EGR27530.1 - 0.016 15.2 1.4 0.016 15.2 1.4 3.5 4 0 0 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.6 EGR27530.1 - 0.13 12.0 6.6 0.44 10.3 0.8 3.3 2 1 1 3 3 3 0 Leucine rich repeat LRR_1 PF00560.33 EGR27530.1 - 0.18 12.5 10.3 1 10.2 0.0 4.1 3 1 0 3 3 3 0 Leucine Rich Repeat Radical_SAM_N PF08497.10 EGR27530.1 - 0.66 9.2 3.6 0.95 8.6 3.6 1.1 1 0 0 1 1 1 0 Radical SAM N-terminal LRR_4 PF12799.7 EGR27530.1 - 1.4 9.4 10.8 0.64 10.5 1.7 3.4 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) WD40 PF00400.32 EGR27531.1 - 5.6e-08 33.3 0.0 0.0019 19.0 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR27531.1 - 2.5e-06 27.7 0.0 0.04 14.2 0.0 3.5 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGR27531.1 - 0.007 16.3 0.0 0.018 14.9 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor eIF2A CPSF_A PF03178.15 EGR27531.1 - 0.064 12.6 0.0 0.48 9.7 0.0 2.0 1 1 1 2 2 2 0 CPSF A subunit region ABC2_membrane_3 PF12698.7 EGR27532.1 - 0.07 12.2 14.8 0.091 11.8 14.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein OppC_N PF12911.7 EGR27532.1 - 0.11 12.6 2.6 0.21 11.6 2.6 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C SOGA PF11365.8 EGR27532.1 - 0.32 12.1 13.8 0.29 12.3 11.6 2.2 1 1 0 1 1 1 0 Protein SOGA PDR_CDR PF06422.12 EGR27532.1 - 0.38 10.7 3.8 0.22 11.4 1.6 1.8 2 0 0 2 2 2 0 CDR ABC transporter ASL_C PF08328.11 EGR27532.1 - 0.47 10.6 11.5 0.59 10.2 10.0 1.9 1 1 1 2 2 2 0 Adenylosuccinate lyase C-terminal SNARE PF05739.19 EGR27532.1 - 0.72 9.9 15.6 2.4 8.2 15.6 1.9 1 1 0 1 1 1 0 SNARE domain Radial_spoke PF04712.12 EGR27532.1 - 1.6 7.5 15.1 1.9 7.3 15.1 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein Peptidase_S46 PF10459.9 EGR27532.1 - 2.6 6.6 12.4 3.5 6.2 12.4 1.1 1 0 0 1 1 1 0 Peptidase S46 DUF2207 PF09972.9 EGR27532.1 - 3.8 6.2 15.7 6.3 5.4 15.6 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Ribosomal_L16 PF00252.18 EGR27534.1 - 0.032 14.2 2.5 0.052 13.6 2.2 1.8 1 1 0 1 1 1 0 Ribosomal protein L16p/L10e ZapB PF06005.12 EGR27535.1 - 4.6e-05 23.8 9.1 0.0058 17.0 1.1 2.1 1 1 1 2 2 2 2 Cell division protein ZapB Glycoprotein_B PF00606.18 EGR27535.1 - 0.016 14.7 0.4 0.024 14.1 0.3 1.3 1 1 0 1 1 1 0 Herpesvirus Glycoprotein B ectodomain DUF641 PF04859.12 EGR27535.1 - 0.029 14.7 1.7 0.12 12.7 1.8 1.8 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) HMMR_N PF15905.5 EGR27535.1 - 0.036 13.5 3.9 0.045 13.2 3.9 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal DUF4201 PF13870.6 EGR27535.1 - 0.042 13.6 5.0 0.051 13.3 5.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF1192 PF06698.11 EGR27535.1 - 0.095 12.8 0.1 13 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Csm1_N PF18504.1 EGR27535.1 - 0.098 13.0 2.4 5.6 7.4 0.3 2.3 1 1 1 2 2 2 0 Csm1 N-terminal domain GIT_CC PF16559.5 EGR27535.1 - 0.19 11.6 8.9 0.17 11.8 1.7 2.2 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor DASH_Dad3 PF08656.10 EGR27535.1 - 0.3 11.2 3.4 2.4 8.3 3.4 2.1 1 1 0 1 1 1 0 DASH complex subunit Dad3 JAKMIP_CC3 PF16034.5 EGR27535.1 - 0.43 10.5 7.7 18 5.2 7.7 2.1 1 1 0 1 1 1 0 JAKMIP CC3 domain TolA_bind_tri PF16331.5 EGR27535.1 - 1.1 9.3 11.0 0.85 9.7 1.9 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation Lebercilin PF15619.6 EGR27535.1 - 2.4 7.8 10.2 3.7 7.2 1.3 2.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease HALZ PF02183.18 EGR27535.1 - 4.4 7.6 9.7 0.77 10.0 1.6 2.7 3 0 0 3 3 3 0 Homeobox associated leucine zipper bZIP_2 PF07716.15 EGR27535.1 - 4.5 7.4 8.9 3.4 7.8 0.8 3.1 3 1 0 3 3 3 0 Basic region leucine zipper TSC22 PF01166.18 EGR27535.1 - 7.4 7.0 8.6 28 5.1 0.7 2.8 2 1 0 2 2 2 0 TSC-22/dip/bun family DUF1269 PF06897.12 EGR27536.1 - 0.00027 21.2 0.4 0.00027 21.2 0.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1269) DUF4112 PF13430.6 EGR27536.1 - 0.0019 18.4 0.9 1.3 9.4 0.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4112) Gly-zipper_Omp PF13488.6 EGR27536.1 - 0.0021 18.0 5.4 0.0053 16.7 5.4 1.7 1 0 0 1 1 1 1 Glycine zipper Gly-zipper_YMGG PF13441.6 EGR27536.1 - 0.042 13.6 6.2 0.085 12.6 6.2 1.5 1 1 0 1 1 1 0 YMGG-like Gly-zipper SpoV PF08183.11 EGR27536.1 - 0.51 10.3 3.7 1.6 8.7 3.7 1.9 1 0 0 1 1 1 0 Stage V sporulation protein family Rick_17kDa_Anti PF05433.15 EGR27536.1 - 0.85 9.5 11.3 0.12 12.2 5.2 2.3 2 0 0 2 2 2 0 Glycine zipper 2TM domain Adaptin_N PF01602.20 EGR27538.1 - 6.7e-33 114.0 32.1 1.4e-32 113.0 32.1 1.5 1 1 0 1 1 1 1 Adaptin N terminal region RPAP3_C PF13877.6 EGR27538.1 - 0.0075 16.8 6.8 0.015 15.8 0.7 3.1 2 1 0 2 2 2 1 Potential Monad-binding region of RPAP3 DUF1091 PF06477.13 EGR27538.1 - 0.049 14.1 2.1 0.21 12.1 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1091) RTP1_C1 PF10363.9 EGR27538.1 - 2.5 8.3 6.9 1.9 8.7 1.6 3.0 2 2 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Pkinase PF00069.25 EGR27539.1 - 1.7e-60 204.6 0.0 1.7e-60 204.6 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27539.1 - 5.5e-44 150.4 0.0 1.1e-43 149.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PIH1 PF08190.12 EGR27539.1 - 1.5e-30 105.9 4.8 1.8e-30 105.6 3.2 2.1 2 0 0 2 2 2 1 PIH1 N-terminal domain PIH1_CS PF18201.1 EGR27539.1 - 6.4e-10 39.3 0.0 1.8e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 PIH1 CS-like domain Pkinase_fungal PF17667.1 EGR27539.1 - 0.00074 18.4 0.0 0.0023 16.8 0.0 1.8 1 0 0 1 1 1 1 Fungal protein kinase Pam16 PF03656.13 EGR27539.1 - 0.023 14.7 3.3 0.089 12.8 3.3 2.0 1 0 0 1 1 1 0 Pam16 RBD-FIP PF09457.10 EGR27539.1 - 0.041 13.8 3.1 1.4 8.9 0.4 3.2 2 0 0 2 2 2 0 FIP domain DUF4667 PF15700.5 EGR27539.1 - 0.095 12.8 3.1 0.15 12.2 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) TetR PF13972.6 EGR27539.1 - 7.4 6.3 6.8 6.1 6.5 0.1 3.2 3 1 1 4 4 4 0 Bacterial transcriptional repressor TPR_1 PF00515.28 EGR27540.1 - 4.2e-29 99.1 42.6 2.7e-09 36.5 0.3 9.0 9 0 0 9 9 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 EGR27540.1 - 6e-26 88.4 38.7 8e-06 25.6 0.1 10.3 11 0 0 11 11 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 EGR27540.1 - 1e-22 78.4 33.3 5.7e-08 32.4 0.3 8.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_12 PF13424.6 EGR27540.1 - 1.3e-14 54.3 8.1 2.1e-10 40.7 0.5 5.7 6 1 1 7 7 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR27540.1 - 6.4e-11 42.3 2.8 6.4e-11 42.3 2.8 6.0 4 1 2 6 6 6 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGR27540.1 - 7.5e-11 42.4 4.6 0.07 13.6 0.2 5.2 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGR27540.1 - 3.2e-10 39.5 27.9 2.6e-05 23.8 0.9 6.8 5 2 2 7 7 7 3 TPR repeat TPR_14 PF13428.6 EGR27540.1 - 8e-09 35.6 0.1 0.38 11.7 0.0 6.6 5 2 2 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGR27540.1 - 8.1e-09 35.6 15.9 0.54 11.0 0.1 8.6 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGR27540.1 - 1.1e-08 34.9 31.8 3.8e-05 23.8 0.6 9.1 10 1 1 11 11 10 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGR27540.1 - 1.6e-08 33.9 10.3 0.0016 18.4 0.0 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGR27540.1 - 5.9e-08 33.2 0.2 5.4 7.7 0.0 5.6 3 2 1 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGR27540.1 - 1.4e-07 31.1 15.6 0.0011 18.8 0.1 5.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_21 PF09976.9 EGR27540.1 - 0.0089 15.7 2.7 2.6 7.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat-like domain Fis1_TPR_C PF14853.6 EGR27540.1 - 0.01 15.9 12.2 0.02 14.9 1.2 4.5 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat POR_N PF01855.19 EGR27540.1 - 0.061 13.1 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg TPR_9 PF13371.6 EGR27540.1 - 0.062 13.5 0.0 32 4.7 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 EGR27540.1 - 0.21 11.9 1.3 17 5.9 0.0 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat Ribosomal_L7Ae PF01248.26 EGR27541.1 - 3.6e-25 87.5 0.5 4.9e-25 87.1 0.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family E1-E2_ATPase PF00122.20 EGR27542.1 - 9e-47 158.9 0.5 1.1e-44 152.2 0.2 2.5 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGR27542.1 - 2.6e-39 134.8 0.7 2.6e-39 134.8 0.7 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGR27542.1 - 2.5e-20 73.7 0.0 2.8e-17 63.7 0.0 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGR27542.1 - 3.6e-12 46.2 0.1 8.9e-12 44.9 0.1 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGR27542.1 - 1.1e-11 44.2 0.3 2.9e-11 42.9 0.0 1.9 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Nucleos_tra2_N PF01773.20 EGR27542.1 - 0.075 13.7 0.2 0.075 13.7 0.2 3.0 3 0 0 3 3 3 0 Na+ dependent nucleoside transporter N-terminus Bax1-I PF01027.20 EGR27543.1 - 1.8e-44 152.1 36.0 2.1e-44 151.8 36.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Gaa1 PF04114.14 EGR27543.1 - 0.0047 16.0 7.3 0.0063 15.6 7.3 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component DUF2207 PF09972.9 EGR27543.1 - 0.0048 15.7 0.2 0.0048 15.7 0.2 2.2 1 1 1 2 2 2 1 Predicted membrane protein (DUF2207) MgtE PF01769.16 EGR27543.1 - 0.0061 16.9 7.3 0.0061 16.9 7.3 3.1 1 1 1 2 2 2 1 Divalent cation transporter DUF3043 PF11241.8 EGR27543.1 - 0.04 14.0 0.0 0.04 14.0 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3043) Eapp_C PF10238.9 EGR27543.1 - 0.14 12.2 3.0 0.18 11.8 3.0 1.2 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF2070 PF09843.9 EGR27543.1 - 0.79 7.9 21.7 0.99 7.6 21.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) US10 PF17617.2 EGR27543.1 - 5.1 7.2 6.2 8.9 6.4 5.7 1.6 1 1 0 1 1 1 0 Viral unique short region 10 DUF1772 PF08592.11 EGR27543.1 - 8.8 6.6 8.4 2 8.7 3.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) Arm PF00514.23 EGR27544.1 - 1.1e-07 31.6 0.8 0.32 11.1 0.0 4.5 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EGR27544.1 - 0.00025 21.0 0.3 0.036 14.3 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat IFRD PF05004.13 EGR27544.1 - 0.00031 19.9 0.4 0.25 10.4 0.0 2.9 2 1 0 2 2 2 2 Interferon-related developmental regulator (IFRD) HEAT_2 PF13646.6 EGR27544.1 - 0.011 16.1 0.0 1.1 9.7 0.0 2.8 3 0 0 3 3 3 0 HEAT repeats HEAT_EZ PF13513.6 EGR27544.1 - 0.037 14.5 0.3 3.9 8.1 0.0 3.0 3 0 0 3 3 3 0 HEAT-like repeat RICTOR_V PF14668.6 EGR27544.1 - 1.5 9.1 3.6 13 6.1 0.0 3.6 4 1 0 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 RNA_pol_Rpb5_C PF01191.19 EGR27545.1 - 9.3e-17 60.7 0.2 1.6e-16 59.9 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain BH4 PF02180.17 EGR27545.1 - 3 7.8 5.6 3.5 7.5 0.0 2.8 3 0 0 3 3 3 0 Bcl-2 homology region 4 HATPase_c PF02518.26 EGR27546.1 - 1.4e-20 73.9 1.3 2.6e-20 73.0 0.7 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGR27546.1 - 8.9e-20 70.9 0.0 1.6e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain DUF5620 PF18522.1 EGR27546.1 - 0.025 15.0 0.2 0.05 14.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5620) HATPase_c_3 PF13589.6 EGR27546.1 - 0.077 12.8 2.0 0.11 12.3 1.4 1.6 1 1 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Enolase_N PF03952.16 EGR27546.1 - 0.11 12.6 0.1 0.26 11.5 0.1 1.6 1 0 0 1 1 1 0 Enolase, N-terminal domain Ras PF00071.22 EGR27547.1 - 7.6e-57 191.4 4.5 1.1e-56 190.9 4.5 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR27547.1 - 4.4e-33 114.0 2.3 9.2e-33 113.0 2.3 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR27547.1 - 3.6e-14 52.6 0.9 4.7e-14 52.2 0.9 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGR27547.1 - 1.2e-08 34.6 2.5 1.6e-08 34.2 2.5 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGR27547.1 - 2.9e-06 27.4 1.5 3.9e-06 26.9 0.3 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGR27547.1 - 6.2e-05 22.6 5.6 0.00019 21.0 5.6 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EGR27547.1 - 0.019 15.2 0.4 0.067 13.5 0.1 2.0 1 1 1 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGR27547.1 - 0.035 14.0 2.8 0.59 10.0 0.1 2.5 1 1 2 3 3 3 0 RsgA GTPase AAA_16 PF13191.6 EGR27547.1 - 0.075 13.4 0.0 0.11 12.9 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain DUF3067 PF11267.8 EGR27547.1 - 0.085 13.5 0.1 0.17 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3067) ATPase PF06745.13 EGR27547.1 - 0.21 10.9 3.3 0.17 11.2 0.6 1.9 1 1 1 2 2 2 0 KaiC ATP-synt_ab PF00006.25 EGR27548.1 - 1.1e-103 345.4 0.0 1.6e-103 344.9 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EGR27548.1 - 4.8e-44 149.1 0.0 9e-44 148.2 0.0 1.5 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EGR27548.1 - 1.1e-13 51.5 0.1 2.2e-13 50.5 0.1 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Peptidase_M8 PF01457.16 EGR27549.1 - 6.7e-29 101.0 0.5 1e-28 100.4 0.5 1.2 1 0 0 1 1 1 1 Leishmanolysin AhpC-TSA PF00578.21 EGR27550.1 - 3.4e-39 133.6 0.0 4.6e-39 133.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGR27550.1 - 2.2e-20 72.8 0.0 3.2e-20 72.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EGR27550.1 - 1.5e-14 53.6 0.2 2.5e-14 52.8 0.2 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 EGR27550.1 - 0.051 13.5 0.2 0.17 11.8 0.1 1.8 2 0 0 2 2 2 0 SCO1/SenC RCC1 PF00415.18 EGR27552.1 - 1.2e-29 102.6 0.2 6.7e-14 52.3 0.1 3.9 4 0 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR27552.1 - 1.1e-16 60.1 10.1 9.5e-09 34.8 0.1 3.3 3 0 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat DivIC PF04977.15 EGR27552.1 - 0.02 14.6 9.3 0.02 14.6 9.3 3.1 3 1 1 4 4 4 0 Septum formation initiator DUF2203 PF09969.9 EGR27552.1 - 3 8.6 7.3 0.8 10.4 3.0 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) SCFA_trans PF02667.14 EGR27552.1 - 3.4 6.5 5.1 4.2 6.3 5.1 1.1 1 0 0 1 1 1 0 Short chain fatty acid transporter Pkinase PF00069.25 EGR27553.1 - 9e-14 51.5 0.0 9.8e-14 51.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27553.1 - 3.3e-08 33.1 0.0 3.3e-08 33.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGR27554.1 - 1.6e-62 211.3 7.5 1.9e-62 211.0 7.5 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27554.1 - 9.8e-37 126.6 1.2 1.2e-36 126.3 1.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27554.1 - 0.00018 20.9 0.8 0.00035 20.0 0.8 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR27554.1 - 0.00026 19.9 1.4 0.00035 19.5 0.1 1.8 2 1 1 3 3 3 1 Fungal protein kinase APH PF01636.23 EGR27554.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinesin PF00225.23 EGR27555.1 - 2.8e-45 154.7 2.1 2.8e-45 154.7 2.1 2.5 2 1 0 2 2 2 1 Kinesin motor domain DUF4472 PF14739.6 EGR27555.1 - 8.8e-29 100.4 14.8 8.8e-29 100.4 14.8 7.8 5 1 3 8 8 8 2 Domain of unknown function (DUF4472) Microtub_bd PF16796.5 EGR27555.1 - 3e-11 43.5 0.1 3e-11 43.5 0.1 3.7 3 1 0 3 3 3 1 Microtubule binding PikAIV_N PF18605.1 EGR27555.1 - 3.9 7.1 13.8 0.25 11.0 4.5 3.5 3 0 0 3 3 3 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain ANAPC4_WD40 PF12894.7 EGR27556.1 - 6.8e-05 23.1 0.1 0.29 11.4 0.0 3.0 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain AFP_2 PF18815.1 EGR27556.1 - 2 8.7 6.2 9.9 6.5 0.4 4.0 3 0 0 3 3 3 0 Bacterial antifreeze protein repeat WD40 PF00400.32 EGR27557.1 - 8.4e-08 32.8 3.3 0.001 19.8 0.0 4.9 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR27557.1 - 7.6e-06 26.2 4.4 0.96 9.8 0.0 4.9 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF4710 PF15828.5 EGR27557.1 - 0.07 13.3 2.0 0.14 12.3 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) DUF2147 PF09917.9 EGR27557.1 - 0.89 10.2 7.7 1.6 9.4 4.7 2.6 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2147) ComC PF03047.14 EGR27557.1 - 1.6 8.6 8.1 0.065 13.0 1.5 2.2 2 0 0 2 2 2 0 COMC family Peptidase_C2 PF00648.21 EGR27558.1 - 3.9e-53 180.4 1.1 5.5e-53 179.9 0.2 1.6 2 0 0 2 2 2 1 Calpain family cysteine protease TPR_12 PF13424.6 EGR27559.1 - 8.6e-25 86.8 5.1 1.4e-08 34.9 0.0 4.2 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGR27559.1 - 8.8e-19 66.5 7.9 1.5e-05 24.6 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGR27559.1 - 1e-15 56.5 4.5 0.00061 19.7 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGR27559.1 - 2.8e-13 49.3 1.8 0.0013 18.5 0.3 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGR27559.1 - 4.8e-13 48.2 7.5 0.00011 22.1 0.1 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGR27559.1 - 8.8e-06 25.3 6.3 0.009 15.7 0.2 4.7 3 1 1 4 4 4 1 TPR repeat TPR_7 PF13176.6 EGR27559.1 - 3.2e-05 23.7 6.8 0.078 13.0 0.2 4.7 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGR27559.1 - 0.0001 21.8 2.7 0.0043 16.5 0.1 3.0 2 1 1 3 3 3 1 MalT-like TPR region TPR_17 PF13431.6 EGR27559.1 - 0.00045 20.4 1.5 0.37 11.3 0.0 4.1 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGR27559.1 - 0.0022 18.6 0.2 30 5.8 0.0 4.8 4 2 1 5 5 5 0 Tetratricopeptide repeat HTH_Bact PF18768.1 EGR27559.1 - 0.018 14.6 0.7 0.56 9.8 0.1 3.2 3 0 0 3 3 3 0 Helix-turn-helix bacterial domain DUF5113 PF17140.4 EGR27559.1 - 0.025 14.4 7.7 0.95 9.3 0.2 4.0 2 1 2 4 4 4 0 Domain of unknown function (DUF5113) MIT PF04212.18 EGR27559.1 - 0.028 14.5 11.1 0.068 13.2 1.3 4.1 3 3 0 3 3 3 0 MIT (microtubule interacting and transport) domain DNA_pol_E_B PF04042.16 EGR27559.1 - 0.036 13.4 0.5 0.094 12.1 0.5 1.7 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B PPR PF01535.20 EGR27559.1 - 0.046 14.0 2.4 0.77 10.1 0.0 3.8 5 0 0 5 5 5 0 PPR repeat TPR_6 PF13174.6 EGR27559.1 - 0.084 13.5 3.8 16 6.4 0.1 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3856 PF12968.7 EGR27559.1 - 0.16 12.1 4.1 5.4 7.1 0.1 3.4 3 1 1 4 4 4 0 Domain of Unknown Function (DUF3856) ANAPC5 PF12862.7 EGR27559.1 - 0.26 11.4 4.6 7.6 6.7 0.2 3.3 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 VPS9 PF02204.18 EGR27560.1 - 1.9e-19 69.8 0.4 2.6e-19 69.4 0.4 1.2 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain AAA PF00004.29 EGR27561.1 - 1.3e-38 132.4 0.0 2.5e-38 131.5 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGR27561.1 - 2.4e-09 36.8 0.0 6.8e-09 35.4 0.0 1.8 1 1 1 2 2 2 1 AAA+ lid domain Vps4_C PF09336.10 EGR27561.1 - 1.3e-08 34.7 0.1 4.6e-08 32.9 0.1 1.9 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 EGR27561.1 - 1e-07 31.8 0.0 2.3e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGR27561.1 - 1.8e-05 24.8 0.2 9.5e-05 22.4 0.2 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGR27561.1 - 0.00047 20.4 1.3 0.17 12.1 0.1 2.8 1 1 2 3 3 3 1 AAA domain TIP49 PF06068.13 EGR27561.1 - 0.00068 18.9 0.2 0.0014 17.9 0.1 1.6 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 EGR27561.1 - 0.0017 18.4 0.0 0.0059 16.6 0.0 2.0 2 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EGR27561.1 - 0.0033 17.2 0.1 3.1 7.5 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_2 PF07724.14 EGR27561.1 - 0.0099 16.0 0.0 0.025 14.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EGR27561.1 - 0.014 15.2 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.6 EGR27561.1 - 0.017 14.7 0.2 5 6.7 0.0 2.9 2 1 1 3 3 3 0 AAA domain AAA_24 PF13479.6 EGR27561.1 - 0.034 13.9 1.5 0.32 10.7 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGR27561.1 - 0.036 14.5 0.7 0.29 11.5 0.7 2.3 1 1 0 1 1 1 0 AAA ATPase domain TniB PF05621.11 EGR27561.1 - 0.049 13.0 0.4 6.5 6.1 0.1 2.8 1 1 2 3 3 3 0 Bacterial TniB protein Mg_chelatase PF01078.21 EGR27561.1 - 0.052 12.9 0.1 0.13 11.6 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGR27561.1 - 0.063 13.8 0.2 0.16 12.5 0.2 2.0 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGR27561.1 - 0.073 13.5 0.9 0.62 10.5 0.0 2.7 3 0 0 3 3 3 0 RNA helicase AAA_7 PF12775.7 EGR27561.1 - 0.86 9.1 4.0 0.57 9.7 0.1 2.6 3 1 0 3 3 3 0 P-loop containing dynein motor region ATPase PF06745.13 EGR27561.1 - 1.2 8.4 10.3 2 7.7 0.1 3.6 2 1 1 4 4 4 0 KaiC MBOAT PF03062.19 EGR27563.1 - 4.8e-27 95.2 30.4 1.3e-26 93.8 30.4 1.8 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF3278 PF11683.8 EGR27563.1 - 0.013 15.6 0.1 0.013 15.6 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3278) DUF4133 PF13571.6 EGR27563.1 - 0.84 10.0 7.0 0.27 11.6 2.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4133) DUF2721 PF11026.8 EGR27566.1 - 1.2 9.0 1.9 4 7.3 0.1 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2721) Metalloenzyme PF01676.18 EGR27567.1 - 5.4e-23 81.6 0.0 2e-22 79.8 0.0 1.8 1 1 0 1 1 1 1 Metalloenzyme superfamily PhosphMutase PF10143.9 EGR27567.1 - 4.6e-14 52.6 0.0 7.3e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Phosphodiest PF01663.22 EGR27567.1 - 0.0023 17.6 0.0 0.0032 17.1 0.0 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Alk_phosphatase PF00245.20 EGR27567.1 - 0.017 14.1 0.1 0.02 13.9 0.1 1.2 1 0 0 1 1 1 0 Alkaline phosphatase DUF4410 PF14366.6 EGR27567.1 - 0.17 11.8 0.1 0.33 10.9 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4410) ATP-synt_D PF01813.17 EGR27568.1 - 1.9e-55 187.7 4.5 2.4e-55 187.4 4.5 1.1 1 0 0 1 1 1 1 ATP synthase subunit D Pkinase PF00069.25 EGR27569.1 - 2.5e-51 174.6 0.2 7.1e-30 104.2 0.0 2.4 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27569.1 - 3.4e-29 101.9 0.0 1.2e-15 57.5 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase eIF-6 PF01912.18 EGR27570.1 - 4.3e-81 271.0 1.0 4.9e-81 270.8 0.4 1.3 2 0 0 2 2 2 1 eIF-6 family WD40 PF00400.32 EGR27571.1 - 7.7e-30 102.5 8.9 0.012 16.5 0.0 11.0 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR27571.1 - 2.1e-09 37.6 2.8 0.2 12.0 0.0 7.3 4 3 3 8 8 8 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGR27571.1 - 1.2e-05 24.8 2.2 0.037 13.3 0.0 3.9 3 1 1 4 4 4 2 WD40-like domain Cyt-b5 PF00173.28 EGR27572.1 - 1.1e-10 41.5 0.2 1.5e-10 41.1 0.2 1.3 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Enolase_C PF00113.22 EGR27572.1 - 0.026 13.7 2.8 0.3 10.3 2.8 2.1 1 1 0 1 1 1 0 Enolase, C-terminal TIM barrel domain Methyltransf_16 PF10294.9 EGR27573.1 - 8.3e-08 32.2 1.3 1.7e-05 24.6 1.3 2.2 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 EGR27573.1 - 9.1e-07 29.5 0.6 6.7e-06 26.8 0.6 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGR27573.1 - 2.1e-05 24.4 0.0 3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGR27573.1 - 2.9e-05 23.9 3.0 0.0005 19.9 3.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGR27573.1 - 4.1e-05 23.1 0.3 0.00049 19.6 0.0 2.0 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EGR27573.1 - 6.9e-05 23.4 0.1 0.0013 19.4 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGR27573.1 - 0.00026 21.7 0.0 0.043 14.5 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGR27573.1 - 0.0017 17.9 0.1 0.0057 16.2 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase small domain NodS PF05401.11 EGR27573.1 - 0.004 16.8 0.4 0.0057 16.3 0.4 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_18 PF12847.7 EGR27573.1 - 0.03 14.3 0.0 0.09 12.7 0.0 1.8 1 1 0 2 2 2 0 Methyltransferase domain MetW PF07021.12 EGR27573.1 - 0.051 13.2 2.3 0.26 10.9 0.1 2.2 1 1 0 2 2 2 0 Methionine biosynthesis protein MetW SRP_TPR_like PF17004.5 EGR27573.1 - 0.061 13.3 3.0 1.9 8.5 0.9 2.2 1 1 1 2 2 2 0 Putative TPR-like repeat Cons_hypoth95 PF03602.15 EGR27573.1 - 0.12 12.0 0.1 0.29 10.8 0.1 1.8 1 1 0 1 1 1 0 Conserved hypothetical protein 95 Ank_2 PF12796.7 EGR27574.1 - 6.4e-12 45.9 0.0 9.7e-12 45.3 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGR27574.1 - 2.9e-10 40.2 0.0 6.9e-06 26.2 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR27574.1 - 4.8e-09 35.7 0.0 0.00011 22.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EGR27574.1 - 1.1e-08 35.4 0.0 2e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGR27574.1 - 8.3e-06 26.0 0.0 0.00013 22.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat tRNA-synt_2d PF01409.20 EGR27575.1 - 1.3e-45 155.8 2.1 6.3e-45 153.6 2.1 1.9 1 1 0 1 1 1 1 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EGR27575.1 - 1.3e-17 64.0 0.2 7.3e-16 58.4 0.0 3.0 3 0 0 3 3 3 1 Ferredoxin-fold anticodon binding domain AGOG PF09171.10 EGR27575.1 - 0.016 14.5 0.1 0.027 13.8 0.1 1.3 1 0 0 1 1 1 0 N-glycosylase/DNA lyase Ins145_P3_rec PF08709.11 EGR27577.1 - 2e-10 40.2 4.0 2e-10 40.2 4.0 2.6 1 1 1 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 EGR27577.1 - 7.5e-06 25.9 0.2 7.5e-06 25.9 0.2 3.4 2 1 0 2 2 2 1 MIR domain UPF0154 PF03672.13 EGR27577.1 - 0.38 10.8 5.9 0.16 12.0 0.7 3.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) TRAPP PF04051.16 EGR27578.1 - 3.4e-22 78.7 0.0 3.6e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component BT1 PF03092.16 EGR27579.1 - 1.4e-71 241.3 21.2 8.3e-43 146.4 12.9 2.1 1 1 1 2 2 2 2 BT1 family MFS_1 PF07690.16 EGR27579.1 - 7.8e-23 81.0 15.8 1.7e-22 79.8 14.6 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 EGR27579.1 - 3.4e-10 39.5 0.3 1.2e-07 31.1 0.2 2.2 2 0 0 2 2 2 2 PUCC protein Wzz PF02706.15 EGR27579.1 - 5.5 7.4 6.9 7.2 7.0 0.5 3.6 4 0 0 4 4 4 0 Chain length determinant protein ubiquitin PF00240.23 EGR27580.1 - 1.2e-33 114.7 0.4 2.3e-33 113.8 0.3 1.5 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_L40e PF01020.17 EGR27580.1 - 1.8e-27 95.0 12.0 2.7e-27 94.4 12.0 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 EGR27580.1 - 2.8e-15 55.9 0.9 4e-15 55.4 0.5 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGR27580.1 - 8.9e-05 22.9 0.1 0.00035 21.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EGR27580.1 - 0.0062 16.9 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGR27580.1 - 0.0085 16.2 0.1 0.015 15.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EGR27580.1 - 0.025 14.5 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EGR27580.1 - 0.057 14.0 0.0 0.078 13.5 0.0 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EGR27580.1 - 0.064 13.3 1.0 6.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain PAS PF00989.25 EGR27581.1 - 2.6e-06 27.4 0.0 3.5e-05 23.8 0.0 2.8 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EGR27581.1 - 3.2e-05 24.1 6.5 0.00048 20.4 0.0 3.5 3 0 0 3 3 3 2 PAS domain PBP1_TM PF14812.6 EGR27581.1 - 0.018 15.4 3.4 0.77 10.2 0.1 3.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FtsX PF02687.21 EGR27581.1 - 0.95 10.0 11.2 0.47 11.0 0.3 3.3 3 0 0 3 3 3 0 FtsX-like permease family HTH_6 PF01418.17 EGR27581.1 - 2.7 8.1 5.5 0.98 9.4 1.6 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Colicin_immun PF09204.10 EGR27582.1 - 0.073 13.6 1.3 0.073 13.6 1.3 2.9 2 1 2 4 4 4 0 Bacterial self-protective colicin-like immunity SIS PF01380.22 EGR27583.1 - 1.1e-35 122.3 0.8 8.2e-18 64.5 0.1 2.6 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EGR27583.1 - 4e-18 65.9 0.0 8e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EGR27583.1 - 6.7e-14 51.9 0.0 2.1e-13 50.3 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_4 PF13230.6 EGR27583.1 - 3.1e-05 23.0 0.0 5.2e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II bact-PGI_C PF10432.9 EGR27583.1 - 0.0095 16.0 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial phospho-glucose isomerase C-terminal SIS domain DUF4727 PF15856.5 EGR27583.1 - 0.047 13.3 0.0 0.08 12.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4727) Citrate_synt PF00285.21 EGR27584.1 - 4.4e-120 401.0 0.0 5.3e-120 400.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF1344 PF07076.11 EGR27584.1 - 0.063 13.2 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1344) PP2C PF00481.21 EGR27585.1 - 1.2e-47 162.8 0.1 1.7e-47 162.2 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGR27585.1 - 2.9e-12 46.7 0.0 9.4e-10 38.5 0.0 2.3 2 1 1 3 3 3 2 Protein phosphatase 2C SpoIIE PF07228.12 EGR27585.1 - 0.00011 22.2 0.0 0.45 10.4 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) DUF4407 PF14362.6 EGR27586.1 - 0.016 14.6 6.9 0.012 15.0 5.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF3073 PF11273.8 EGR27586.1 - 1.2 9.9 4.3 2.7 8.8 0.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3073) DUF5339 PF17274.2 EGR27586.1 - 2 9.3 8.8 0.6 11.0 1.3 2.9 2 0 0 2 2 2 0 Family of unknown function (DUF5339) YkyA PF10368.9 EGR27586.1 - 2.1 8.0 26.3 0.71 9.5 22.2 2.3 2 1 0 2 2 2 0 Putative cell-wall binding lipoprotein DUF1664 PF07889.12 EGR27586.1 - 2.4 8.2 10.0 0.68 10.0 4.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF3887 PF13026.6 EGR27586.1 - 5.3 7.9 7.0 1.6 9.6 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3887) DUF4728 PF15860.5 EGR27587.1 - 0.049 14.3 0.4 0.16 12.6 0.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4728) PI3_PI4_kinase PF00454.27 EGR27588.1 - 3.6e-47 161.3 1.2 3.6e-47 161.3 1.2 2.0 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGR27588.1 - 5.3e-20 71.6 2.5 1.5e-19 70.1 2.5 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF5385 PF17359.2 EGR27588.1 - 0.0048 16.5 0.7 0.012 15.2 0.7 1.6 1 0 0 1 1 1 1 Family of unknown function (DUF5385) DUF4135 PF13575.6 EGR27588.1 - 0.057 12.7 0.0 0.14 11.5 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4135) PK PF00224.21 EGR27591.1 - 2.3e-55 187.9 7.5 1e-44 152.9 3.6 2.1 2 0 0 2 2 2 2 Pyruvate kinase, barrel domain Type2_restr_D3 PF16902.5 EGR27591.1 - 0.045 13.7 0.6 0.045 13.7 0.6 2.5 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain HpcH_HpaI PF03328.14 EGR27591.1 - 0.15 11.2 0.5 0.32 10.1 0.5 1.5 1 0 0 1 1 1 0 HpcH/HpaI aldolase/citrate lyase family Pkinase PF00069.25 EGR27593.1 - 1.3e-40 139.5 0.0 3.7e-37 128.1 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27593.1 - 3.3e-11 43.0 0.0 1.6e-10 40.7 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 EGR27593.1 - 0.038 13.1 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Haspin_kinase PF12330.8 EGR27593.1 - 0.051 12.5 0.0 0.077 11.9 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EGR27593.1 - 0.07 13.0 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EGR27593.1 - 0.092 12.0 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Cnd1 PF12717.7 EGR27594.1 - 1.4e-39 135.7 2.8 1.4e-39 135.7 2.8 4.4 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EGR27594.1 - 0.052 13.7 0.5 0.052 13.7 0.5 4.4 4 2 3 7 7 7 0 Required for nuclear transport of RNA pol II C-terminus 1 Glyco_hydro_67N PF03648.14 EGR27594.1 - 1.3 9.3 11.2 0.19 12.0 1.7 3.4 2 1 1 3 3 3 0 Glycosyl hydrolase family 67 N-terminus TPR_1 PF00515.28 EGR27595.1 - 1.3e-09 37.5 13.6 2.9e-06 26.9 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGR27595.1 - 6.4e-09 35.2 12.2 5.7e-05 22.9 0.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGR27595.1 - 6.1e-07 29.9 0.1 0.13 12.8 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGR27595.1 - 1.4e-06 28.3 1.3 0.013 15.8 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGR27595.1 - 2.6e-06 27.2 15.3 0.0011 19.0 0.1 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR27595.1 - 2.6e-06 27.5 2.3 2.6e-06 27.5 2.3 2.7 3 0 0 3 3 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGR27595.1 - 2.5e-05 24.6 4.1 2.1 9.2 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.6 EGR27595.1 - 3.1e-05 23.3 0.2 6.3e-05 22.3 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGR27595.1 - 0.0001 22.0 0.0 0.061 13.4 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGR27595.1 - 0.00011 22.5 0.9 0.0075 16.5 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat NSF PF02071.20 EGR27595.1 - 0.00062 20.0 4.7 24 6.3 0.0 5.4 4 0 0 4 4 4 0 Aromatic-di-Alanine (AdAR) repeat TPR_14 PF13428.6 EGR27595.1 - 0.00073 20.1 0.0 10 7.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGR27595.1 - 0.00084 19.0 0.3 0.016 14.9 0.1 3.1 2 1 1 3 3 3 1 TPR repeat TPR_16 PF13432.6 EGR27595.1 - 0.0013 19.3 0.0 0.73 10.5 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat MukF_C PF17193.4 EGR27595.1 - 0.0068 16.6 2.9 0.49 10.5 0.2 2.3 2 0 0 2 2 2 1 MukF C-terminal domain TPR_9 PF13371.6 EGR27595.1 - 0.0077 16.4 0.0 0.048 13.8 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat zf-C4_Topoisom PF01396.19 EGR27595.1 - 2 8.3 6.4 0.54 10.1 2.9 2.0 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger Pkinase PF00069.25 EGR27596.1 - 6.7e-06 25.7 2.7 3.4e-05 23.4 2.7 2.0 1 1 0 1 1 1 1 Protein kinase domain ADK PF00406.22 EGR27597.1 - 6e-51 172.5 1.1 3.5e-29 101.8 0.0 2.4 2 1 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 EGR27597.1 - 1.3e-30 106.6 0.4 1.7e-14 54.4 0.0 2.7 3 0 0 3 3 2 2 AAA domain AAA_18 PF13238.6 EGR27597.1 - 9.4e-12 45.6 3.5 1.2e-07 32.3 0.0 3.9 2 2 2 4 4 4 2 AAA domain Hydin_ADK PF17213.3 EGR27597.1 - 5.3e-08 33.4 0.2 0.066 13.5 0.0 3.4 2 1 1 3 3 3 3 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 EGR27597.1 - 5.9e-08 33.0 0.1 0.0019 18.4 0.0 3.5 4 0 0 4 4 3 2 AAA domain AAA PF00004.29 EGR27597.1 - 7.1e-07 29.7 0.2 0.015 15.7 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 EGR27597.1 - 3.6e-06 26.9 0.0 0.003 17.3 0.0 2.6 2 0 0 2 2 2 2 Cytidylate kinase AAA_5 PF07728.14 EGR27597.1 - 2.5e-05 24.3 0.1 0.028 14.4 0.1 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGR27597.1 - 8.2e-05 22.4 0.1 0.18 11.5 0.0 2.3 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGR27597.1 - 0.00036 19.9 0.4 0.23 10.6 0.1 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain Ploopntkinase3 PF18751.1 EGR27597.1 - 0.00065 19.7 0.0 0.13 12.1 0.0 2.3 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_28 PF13521.6 EGR27597.1 - 0.00069 19.9 0.0 0.033 14.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGR27597.1 - 0.00083 19.1 0.0 0.12 12.0 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein Cytidylate_kin2 PF13189.6 EGR27597.1 - 0.00098 19.3 2.2 1.2 9.2 0.0 3.8 3 1 0 4 4 4 1 Cytidylate kinase-like family DUF5586 PF17824.1 EGR27597.1 - 0.0022 17.2 0.6 0.0048 16.1 0.1 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5586) Methyltransf_8 PF05148.15 EGR27597.1 - 0.0024 17.8 0.0 0.0054 16.6 0.0 1.6 1 0 0 1 1 1 1 Hypothetical methyltransferase SKI PF01202.22 EGR27597.1 - 0.0038 17.4 0.1 0.22 11.7 0.0 2.9 2 0 0 2 2 2 1 Shikimate kinase AAA_16 PF13191.6 EGR27597.1 - 0.0057 17.0 0.0 0.038 14.4 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 EGR27597.1 - 0.0067 16.4 0.7 0.037 13.9 0.0 2.5 3 0 0 3 3 3 1 Rad17 P-loop domain ABC_tran PF00005.27 EGR27597.1 - 0.0079 16.7 0.9 0.41 11.2 0.1 2.6 2 0 0 2 2 2 1 ABC transporter Sigma54_activ_2 PF14532.6 EGR27597.1 - 0.0084 16.2 0.7 4.7 7.3 0.0 3.9 4 1 0 4 4 3 1 Sigma-54 interaction domain AAA_22 PF13401.6 EGR27597.1 - 0.0097 16.2 0.3 0.11 12.8 0.0 2.7 3 0 0 3 3 3 1 AAA domain PduV-EutP PF10662.9 EGR27597.1 - 0.017 14.9 0.1 0.27 11.0 0.1 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation dNK PF01712.19 EGR27597.1 - 0.021 14.7 4.4 3.7 7.3 0.0 3.6 4 0 0 4 4 3 0 Deoxynucleoside kinase FtsX_ECD PF18075.1 EGR27597.1 - 0.029 15.0 5.4 0.34 11.6 0.1 3.4 4 0 0 4 4 2 0 FtsX extracellular domain SRPRB PF09439.10 EGR27597.1 - 0.04 13.4 1.9 0.97 8.8 0.1 2.7 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit Mg_chelatase PF01078.21 EGR27597.1 - 0.045 13.1 0.0 0.92 8.9 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGR27597.1 - 0.05 13.3 0.4 0.35 10.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGR27597.1 - 0.091 13.2 0.3 0.87 10.0 0.0 2.7 3 0 0 3 3 2 0 RNA helicase AAA_7 PF12775.7 EGR27597.1 - 0.11 12.0 1.2 2.8 7.4 0.0 2.9 3 0 0 3 3 2 0 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EGR27597.1 - 0.11 12.5 0.2 1.1 9.3 0.0 2.6 3 0 0 3 3 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 EGR27597.1 - 0.12 11.6 3.5 2.1 7.4 0.0 3.2 4 0 0 4 4 3 0 NB-ARC domain DUF3546 PF12066.8 EGR27597.1 - 0.4 10.9 5.4 8.2 6.7 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3546) Guanylate_kin PF00625.21 EGR27597.1 - 1.8 8.2 9.0 4.7 6.9 0.0 3.7 3 1 0 3 3 3 0 Guanylate kinase FA_desaturase PF00487.24 EGR27598.1 - 2e-24 86.8 19.1 3.2e-24 86.1 19.1 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Peptidase_M60 PF13402.6 EGR27598.1 - 0.027 14.0 0.1 0.054 13.0 0.1 1.5 1 0 0 1 1 1 0 Peptidase M60, enhancin and enhancin-like CRAL_TRIO_2 PF13716.6 EGR27598.1 - 0.028 14.6 0.3 0.077 13.2 0.3 1.8 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Acetyltransf_1 PF00583.25 EGR27599.1 - 3.5e-10 40.1 0.0 4.4e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGR27599.1 - 4.5e-08 33.1 0.0 6.1e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGR27599.1 - 1.8e-07 31.5 0.0 2.3e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGR27599.1 - 1.5e-06 28.1 0.0 2.4e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EGR27599.1 - 0.00039 20.5 0.0 0.00059 19.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGR27599.1 - 0.00057 20.1 0.1 0.00071 19.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EGR27599.1 - 0.07 13.1 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase 2-oxoacid_dh PF00198.23 EGR27600.1 - 1.3e-78 263.7 0.0 1.9e-78 263.2 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGR27600.1 - 4.2e-29 100.2 0.8 2.3e-13 49.8 0.1 2.6 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.17 EGR27600.1 - 2.4e-14 53.4 0.1 5.3e-14 52.3 0.1 1.6 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EGR27600.1 - 2.4e-08 33.7 2.7 0.14 12.0 0.0 4.9 5 0 0 5 5 5 2 Biotin-lipoyl like Spt20 PF12090.8 EGR27600.1 - 3.6e-05 23.5 25.2 7e-05 22.5 13.3 2.4 2 0 0 2 2 2 2 Spt20 family DUF2118 PF09891.9 EGR27600.1 - 0.00031 20.7 0.0 0.38 10.7 0.0 2.6 2 0 0 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2118) HlyD_3 PF13437.6 EGR27600.1 - 0.0012 19.5 6.7 42 4.9 0.0 5.4 5 0 0 5 5 5 0 HlyD family secretion protein PYNP_C PF07831.13 EGR27600.1 - 0.052 13.2 1.6 7.6 6.3 0.0 3.3 4 0 0 4 4 4 0 Pyrimidine nucleoside phosphorylase C-terminal domain Presenilin PF01080.17 EGR27600.1 - 0.23 10.2 9.4 0.13 11.0 4.4 2.1 2 0 0 2 2 2 0 Presenilin ANAPC_CDC26 PF10471.9 EGR27600.1 - 8.2 7.3 27.5 1.4 9.8 0.5 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Ndc1_Nup PF09531.10 EGR27600.1 - 9.3 4.8 19.3 0.17 10.5 8.7 2.1 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup WD40 PF00400.32 EGR27601.1 - 1.3e-11 44.8 0.0 0.0086 16.9 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR27601.1 - 0.00032 20.9 0.0 0.018 15.3 0.0 3.2 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain EcoRII-N PF09217.10 EGR27601.1 - 0.064 13.0 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Restriction endonuclease EcoRII, N-terminal Pkinase PF00069.25 EGR27602.1 - 9.8e-59 198.9 0.3 9.8e-59 198.9 0.3 2.4 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.29 EGR27602.1 - 2.2e-35 120.6 0.2 6.7e-13 48.5 0.0 3.7 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 EGR27602.1 - 5.9e-26 91.3 0.0 1.2e-25 90.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27602.1 - 4e-07 29.6 0.0 1.9e-06 27.4 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR27602.1 - 0.0012 17.7 0.0 0.0022 16.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Sec23_trunk PF04811.15 EGR27603.1 - 2e-35 122.5 0.3 4.1e-35 121.5 0.3 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain SHIPPO-rpt PF07004.12 EGR27603.1 - 3.1e-18 65.7 65.7 0.00089 20.1 3.9 11.1 11 1 0 11 11 11 8 Sperm-tail PG-rich repeat Sec23_BS PF08033.12 EGR27603.1 - 3.3e-15 56.6 0.1 1.1e-14 54.9 0.1 2.0 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EGR27603.1 - 1.8e-06 27.7 2.5 2.3e-06 27.4 0.3 2.3 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Chromo PF00385.24 EGR27604.1 - 1e-16 60.5 16.4 3.7e-15 55.6 8.6 3.2 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 EGR27604.1 - 0.013 15.6 0.1 3.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Polycomb-like MTF2 factor 2 Tudor-knot PF11717.8 EGR27604.1 - 0.043 13.7 4.9 0.24 11.3 0.4 2.8 3 0 0 3 3 3 0 RNA binding activity-knot of a chromodomain Ndc1_Nup PF09531.10 EGR27604.1 - 1.9 7.1 9.0 2.4 6.8 9.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Dapper PF15268.6 EGR27604.1 - 2.5 6.8 18.7 3 6.6 18.7 1.1 1 0 0 1 1 1 0 Dapper Mem_trans PF03547.18 EGR27604.1 - 3.9 5.8 4.8 4.7 5.5 4.8 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF1387 PF07139.11 EGR27604.1 - 7.1 6.3 27.5 10 5.8 27.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Zip PF02535.22 EGR27604.1 - 9.1 5.4 10.7 14 4.8 10.7 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter ArsA_ATPase PF02374.15 EGR27605.1 - 6e-98 327.8 0.4 8.7e-98 327.3 0.4 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.23 EGR27605.1 - 3.4e-14 53.0 0.2 1.8e-11 44.2 0.0 2.5 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGR27605.1 - 1.8e-13 50.8 1.8 4.1e-13 49.6 0.1 2.3 2 2 0 2 2 2 1 AAA domain ParA PF10609.9 EGR27605.1 - 4.4e-08 32.9 3.7 1.6e-05 24.5 0.1 3.1 2 1 1 3 3 3 2 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 EGR27605.1 - 1.3e-06 28.2 2.4 2.9e-05 23.8 0.2 2.5 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain Fer4_NifH PF00142.18 EGR27605.1 - 3.5e-06 26.7 1.7 6.6e-06 25.8 0.1 2.1 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 EGR27605.1 - 0.00022 20.8 0.0 0.00075 19.1 0.0 1.8 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ MeaB PF03308.16 EGR27605.1 - 0.00054 19.0 0.2 0.0026 16.8 0.0 2.1 2 1 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF4855 PF16147.5 EGR27605.1 - 0.0006 19.0 0.3 0.00088 18.5 0.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4855) AAA_18 PF13238.6 EGR27605.1 - 0.00096 19.7 0.0 0.0024 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EGR27605.1 - 0.0011 18.2 0.7 0.065 12.4 0.2 2.2 2 0 0 2 2 2 1 NB-ARC domain CTP_synth_N PF06418.14 EGR27605.1 - 0.0021 17.4 0.1 0.0056 16.0 0.1 1.7 1 0 0 1 1 1 1 CTP synthase N-terminus ATP_bind_1 PF03029.17 EGR27605.1 - 0.0026 17.6 3.8 0.0034 17.2 0.1 2.7 2 2 1 3 3 3 1 Conserved hypothetical ATP binding protein DUF4473 PF14747.6 EGR27605.1 - 0.003 18.1 0.2 0.87 10.2 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4473) IL5 PF02025.15 EGR27605.1 - 0.003 17.8 0.4 0.42 10.9 0.3 2.6 2 0 0 2 2 2 1 Interleukin 5 MipZ PF09140.11 EGR27605.1 - 0.0053 16.1 0.2 0.073 12.3 0.1 2.3 2 0 0 2 2 2 1 ATPase MipZ Zeta_toxin PF06414.12 EGR27605.1 - 0.0061 15.9 0.1 0.026 13.8 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin DASH_Dad4 PF08650.10 EGR27605.1 - 0.0064 16.4 0.2 0.031 14.2 0.3 2.0 2 0 0 2 2 2 1 DASH complex subunit Dad4 AAA_24 PF13479.6 EGR27605.1 - 0.014 15.1 1.3 0.15 11.7 1.3 2.3 1 1 0 1 1 1 0 AAA domain VirC1 PF07015.11 EGR27605.1 - 0.039 13.3 0.1 1.5 8.0 0.1 2.3 2 0 0 2 2 2 0 VirC1 protein PIF1 PF05970.14 EGR27605.1 - 0.039 13.1 0.9 0.084 12.0 0.1 1.8 2 0 0 2 2 2 0 PIF1-like helicase KTI12 PF08433.10 EGR27605.1 - 0.059 12.8 1.2 0.38 10.1 0.0 2.5 2 1 0 2 2 2 0 Chromatin associated protein KTI12 AAA_30 PF13604.6 EGR27605.1 - 0.063 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGR27605.1 - 0.079 13.4 0.8 1.4 9.4 0.0 2.9 2 1 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 EGR27605.1 - 0.083 13.3 0.0 0.19 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.15 EGR27605.1 - 0.1 12.5 0.3 0.24 11.3 0.3 1.6 1 0 0 1 1 1 0 NTPase T2SSE PF00437.20 EGR27605.1 - 0.11 11.5 0.0 0.26 10.3 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF1611 PF07755.11 EGR27605.1 - 0.12 11.6 0.0 0.33 10.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain DUF87 PF01935.17 EGR27605.1 - 0.14 12.3 4.2 0.73 9.9 4.2 2.3 1 1 0 1 1 1 0 Helicase HerA, central domain LpxK PF02606.14 EGR27605.1 - 0.19 10.8 0.8 0.37 9.8 0.8 1.4 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase MSA-2c PF12238.8 EGR27605.1 - 0.69 9.9 7.3 0.59 10.1 4.0 2.3 2 1 0 2 2 2 0 Merozoite surface antigen 2c ResIII PF04851.15 EGR27605.1 - 0.86 9.6 3.4 0.61 10.1 0.4 2.2 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit DUF4225 PF13988.6 EGR27606.1 - 0.022 14.3 0.2 0.046 13.3 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) IQ_SEC7_PH PF16453.5 EGR27606.1 - 0.052 13.5 1.0 0.084 12.9 1.0 1.3 1 0 0 1 1 1 0 PH domain Mating_N PF12731.7 EGR27606.1 - 0.06 13.4 0.1 0.2 11.8 0.1 1.8 2 0 0 2 2 2 0 Mating-type protein beta 1 Mer2 PF09074.10 EGR27606.1 - 0.12 12.2 4.3 0.92 9.3 4.0 2.2 1 1 0 1 1 1 0 Mer2 Noelin-1 PF12308.8 EGR27606.1 - 0.17 11.9 1.2 1.3 9.1 0.3 2.5 2 1 1 3 3 3 0 Neurogenesis glycoprotein MMR_HSR1 PF01926.23 EGR27607.1 - 8.4e-15 54.8 0.1 1.5e-13 50.8 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGR27607.1 - 3.8e-07 29.8 2.2 1.4e-06 27.9 0.1 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGR27607.1 - 0.0025 17.7 3.8 0.59 10.0 0.0 3.3 4 0 0 4 4 4 2 RsgA GTPase SUIM_assoc PF16619.5 EGR27607.1 - 0.049 13.7 0.0 0.48 10.5 0.0 2.4 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Dynamin_N PF00350.23 EGR27607.1 - 0.21 11.7 0.2 0.21 11.7 0.2 2.9 2 2 1 3 3 3 0 Dynamin family Chitin_synth_1 PF01644.17 EGR27608.1 - 6.8e-45 153.0 2.7 6.8e-45 153.0 2.7 3.5 4 0 0 4 4 4 1 Chitin synthase Chitin_synth_2 PF03142.15 EGR27608.1 - 7.7e-16 57.8 6.2 3e-14 52.6 0.1 3.5 3 1 1 4 4 4 2 Chitin synthase AHD PF17793.1 EGR27608.1 - 0.18 11.6 5.4 0.051 13.4 1.0 2.5 2 0 0 2 2 2 0 ANC1 homology domain (AHD) Glyco_trans_2_3 PF13632.6 EGR27608.1 - 0.19 11.6 2.1 0.53 10.2 0.1 2.4 2 0 0 2 2 2 0 Glycosyl transferase family group 2 DUF3377 PF11857.8 EGR27608.1 - 0.53 10.2 2.3 0.72 9.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Gastrin PF00918.17 EGR27608.1 - 2.1 9.4 5.4 6.1 7.8 2.4 2.9 2 0 0 2 2 2 0 Gastrin/cholecystokinin family NINJA_B PF16136.5 EGR27608.1 - 2.1 8.7 4.5 6.2 7.2 4.5 1.7 1 0 0 1 1 1 0 Putative nuclear localisation signal HARP PF07443.13 EGR27609.1 - 0.1 12.2 0.9 0.23 11.1 0.1 2.0 2 0 0 2 2 2 0 HepA-related protein (HARP) polyprenyl_synt PF00348.17 EGR27610.1 - 4.5e-06 25.9 0.1 5.3e-06 25.7 0.1 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase Complex1_51K PF01512.17 EGR27610.1 - 0.1 12.5 0.2 0.19 11.6 0.1 1.5 1 1 0 1 1 1 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit Pkinase PF00069.25 EGR27611.1 - 2.3e-62 210.8 0.3 2.7e-62 210.5 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27611.1 - 7.7e-34 117.1 0.0 1.4e-33 116.3 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EGR27611.1 - 0.00028 20.5 0.0 0.00063 19.4 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EGR27611.1 - 0.00042 19.7 0.2 0.0015 17.9 0.1 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EGR27611.1 - 0.0082 15.5 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR27611.1 - 0.075 12.9 0.0 0.099 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Guanylate_cyc PF00211.20 EGR27612.1 - 1.3e-14 54.3 0.0 2.5e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Presenilin PF01080.17 EGR27612.1 - 0.028 13.2 11.0 0.074 11.8 11.0 1.7 1 0 0 1 1 1 0 Presenilin Mem_trans PF03547.18 EGR27612.1 - 0.38 9.1 5.6 0.79 8.0 5.6 1.5 1 0 0 1 1 1 0 Membrane transport protein Zip PF02535.22 EGR27612.1 - 1.6 7.9 5.9 2.9 7.0 5.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Dapper PF15268.6 EGR27612.1 - 2.1 7.1 17.8 2.8 6.7 17.8 1.1 1 0 0 1 1 1 0 Dapper DUF4407 PF14362.6 EGR27612.1 - 2.6 7.3 8.0 4.6 6.5 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.16 EGR27612.1 - 4.5 7.3 7.5 12 5.8 7.5 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TGT PF01702.18 EGR27613.1 - 0.56 9.3 9.4 0.025 13.7 1.2 2.1 1 1 1 2 2 2 0 Queuine tRNA-ribosyltransferase AAA PF00004.29 EGR27614.1 - 2.2e-37 128.5 0.0 4e-37 127.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGR27614.1 - 3.7e-06 27.0 0.0 2e-05 24.6 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGR27614.1 - 4.6e-06 26.5 0.0 1.7e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EGR27614.1 - 5.2e-06 26.5 0.0 1.1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGR27614.1 - 8.9e-06 26.0 0.5 0.0033 17.7 0.2 2.9 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 EGR27614.1 - 1.1e-05 25.6 0.0 2.7e-05 24.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGR27614.1 - 3.8e-05 24.2 0.1 0.038 14.4 0.0 2.7 2 1 1 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.22 EGR27614.1 - 0.00012 22.4 0.2 0.00041 20.7 0.0 2.1 3 0 0 3 3 1 1 RNA helicase AAA_lid_3 PF17862.1 EGR27614.1 - 0.00075 19.3 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_33 PF13671.6 EGR27614.1 - 0.0012 19.0 0.0 0.0038 17.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EGR27614.1 - 0.0013 18.7 0.6 1.2 9.0 0.0 2.4 1 1 1 2 2 2 2 NACHT domain AAA_28 PF13521.6 EGR27614.1 - 0.0015 18.8 0.0 0.017 15.4 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.6 EGR27614.1 - 0.0016 19.0 0.0 0.0078 16.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EGR27614.1 - 0.0043 16.3 0.2 0.018 14.3 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_11 PF13086.6 EGR27614.1 - 0.006 16.4 0.9 0.017 14.9 0.9 1.9 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGR27614.1 - 0.014 14.4 0.0 0.078 12.0 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein Alpha-mann_mid PF09261.11 EGR27614.1 - 0.015 15.4 0.0 2.2 8.5 0.0 2.4 2 0 0 2 2 2 0 Alpha mannosidase middle domain AAA_17 PF13207.6 EGR27614.1 - 0.017 15.5 0.0 0.061 13.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGR27614.1 - 0.018 14.7 0.0 0.049 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 EGR27614.1 - 0.018 14.7 0.1 0.37 10.5 0.1 2.3 1 1 0 1 1 1 0 Sigma-54 interaction domain Rad17 PF03215.15 EGR27614.1 - 0.044 13.7 0.1 0.58 10.1 0.0 2.3 2 1 0 3 3 2 0 Rad17 P-loop domain Prefoldin_3 PF13758.6 EGR27614.1 - 0.051 13.6 0.0 0.23 11.5 0.0 2.0 2 0 0 2 2 2 0 Prefoldin subunit Mg_chelatase PF01078.21 EGR27614.1 - 0.061 12.7 0.1 0.71 9.2 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ResIII PF04851.15 EGR27614.1 - 0.075 13.0 0.3 0.82 9.7 0.0 2.3 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit TIP49 PF06068.13 EGR27614.1 - 0.085 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_7 PF12775.7 EGR27614.1 - 0.087 12.3 0.0 0.34 10.4 0.0 2.1 1 1 0 1 1 1 0 P-loop containing dynein motor region Synthase_beta PF11421.8 EGR27614.1 - 0.088 13.5 0.7 0.26 12.0 0.3 1.9 2 0 0 2 2 1 0 ATP synthase F1 beta subunit AAA_24 PF13479.6 EGR27614.1 - 0.089 12.5 0.6 0.9 9.2 0.3 2.3 1 1 1 2 2 2 0 AAA domain Guanylate_kin PF00625.21 EGR27614.1 - 0.11 12.2 1.5 0.71 9.5 0.4 2.5 2 1 1 3 3 3 0 Guanylate kinase TsaE PF02367.17 EGR27614.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Torsin PF06309.11 EGR27614.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Torsin CPT PF07931.12 EGR27614.1 - 0.14 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein CPDase PF07823.11 EGR27616.1 - 0.033 13.9 0.4 0.044 13.5 0.4 1.1 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein Syja_N PF02383.18 EGR27616.1 - 0.038 13.3 0.6 0.065 12.5 0.6 1.4 1 0 0 1 1 1 0 SacI homology domain MCM PF00493.23 EGR27618.1 - 2.2e-99 331.1 1.2 5.1e-99 329.9 0.6 2.0 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EGR27618.1 - 1.1e-35 122.3 0.1 1.1e-35 122.3 0.1 2.0 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 EGR27618.1 - 3e-26 91.7 2.9 8.1e-26 90.3 2.9 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EGR27618.1 - 2.5e-08 33.5 0.0 1.3e-07 31.2 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 EGR27618.1 - 4.7e-05 23.9 0.5 4.7e-05 23.9 0.5 3.3 3 1 1 4 4 4 1 MCM N-terminal domain AAA_5 PF07728.14 EGR27618.1 - 0.00059 19.8 0.0 0.0023 18.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EGR27618.1 - 0.0082 15.9 2.8 0.01 15.5 0.1 2.5 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 EGR27618.1 - 0.015 15.2 0.0 0.047 13.6 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pox_G9-A16 PF03003.16 EGR27618.1 - 0.13 12.0 1.5 0.55 10.0 0.4 2.4 2 0 0 2 2 2 0 Pox virus entry-fusion-complex G9/A16 ASH PF15780.5 EGR27619.1 - 1.9e-21 76.1 43.6 0.00015 21.9 0.1 13.6 15 0 0 15 15 15 7 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 EGR27619.1 - 1.9e-15 56.8 33.6 9.7e-05 22.6 0.4 9.2 11 0 0 11 11 11 5 Transmembrane protein 131-like DUF1573 PF07610.11 EGR27619.1 - 3.3e-07 30.2 26.4 0.19 11.8 1.4 9.9 9 0 0 9 9 9 3 Protein of unknown function (DUF1573) Motile_Sperm PF00635.26 EGR27619.1 - 1.7e-05 24.6 51.3 0.0069 16.2 1.1 11.8 12 0 0 12 12 12 5 MSP (Major sperm protein) domain CH PF00307.31 EGR27619.1 - 0.01 16.0 0.1 0.01 16.0 0.1 2.6 2 0 0 2 2 2 0 Calponin homology (CH) domain FokI_N PF02981.15 EGR27619.1 - 0.55 10.4 2.7 1.6 8.9 2.7 1.8 1 0 0 1 1 1 0 Restriction endonuclease FokI, recognition domain PHM7_cyt PF14703.6 EGR27621.1 - 6.7e-05 23.2 0.1 0.024 14.8 0.0 3.0 2 1 1 3 3 3 2 Cytosolic domain of 10TM putative phosphate transporter Zip PF02535.22 EGR27621.1 - 9.6e-05 21.8 0.3 0.0019 17.5 0.1 3.0 4 0 0 4 4 4 1 ZIP Zinc transporter Lyase_1 PF00206.20 EGR27622.1 - 2.2e-47 162.0 0.0 3.2e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 EGR27622.1 - 3.2e-41 140.0 0.1 8.6e-41 138.7 0.1 1.7 1 0 0 1 1 1 1 Adenylosuccinate lyase C-terminal V_ATPase_I PF01496.19 EGR27623.1 - 1.7e-253 843.3 34.6 2.1e-253 843.0 34.6 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family MmgE_PrpD PF03972.14 EGR27623.1 - 4.2e-37 127.7 0.0 1.5e-32 112.7 0.0 3.0 1 1 0 1 1 1 1 MmgE/PrpD family TetR_C_27 PF17935.1 EGR27623.1 - 0.028 14.5 0.1 0.16 12.1 0.1 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain ERG2_Sigma1R PF04622.12 EGR27623.1 - 0.22 10.8 3.1 0.85 8.9 3.1 2.0 1 0 0 1 1 1 0 ERG2 and Sigma1 receptor like protein MFS_1 PF07690.16 EGR27624.1 - 7.5e-37 127.1 29.7 1.6e-33 116.1 11.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EGR27624.1 - 3.8e-10 39.6 0.2 8.1e-09 35.2 0.0 2.1 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EGR27624.1 - 5.9e-10 38.1 29.9 1.3e-07 30.3 6.8 4.8 1 1 2 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 EGR27624.1 - 0.0029 16.1 0.0 0.092 11.1 0.0 2.5 2 1 0 3 3 3 1 Transmembrane secretion effector DUF4307 PF14155.6 EGR27624.1 - 0.21 11.4 0.0 0.49 10.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4307) OAD_gamma PF04277.13 EGR27624.1 - 0.27 11.9 0.1 0.27 11.9 0.1 3.0 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain Peptidase_S49_N PF08496.10 EGR27624.1 - 1.8 8.6 5.7 1.1 9.3 0.6 2.8 3 0 0 3 3 3 0 Peptidase family S49 N-terminal LapA_dom PF06305.11 EGR27624.1 - 6.5 6.6 11.8 40 4.1 0.3 4.9 5 0 0 5 5 5 0 Lipopolysaccharide assembly protein A domain Peptidase_M24 PF00557.24 EGR27625.1 - 1.7e-49 168.3 0.2 2.3e-49 167.9 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EGR27625.1 - 9.6e-18 64.1 0.1 1.8e-17 63.2 0.1 1.5 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 EGR27625.1 - 0.01 15.9 0.1 0.038 14.1 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) Bromodomain PF00439.25 EGR27626.1 - 8.4e-24 83.5 0.3 8.4e-24 83.5 0.3 2.7 2 1 1 3 3 3 1 Bromodomain BET PF17035.5 EGR27626.1 - 2.8e-14 53.0 0.1 9.3e-14 51.4 0.1 2.0 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Ammonium_transp PF00909.21 EGR27627.1 - 1.2e-52 179.0 3.2 1.5e-52 178.7 3.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family LRR_6 PF13516.6 EGR27628.1 - 2.6e-13 48.8 16.0 0.059 13.4 0.7 7.7 7 0 0 7 7 7 6 Leucine Rich repeat LRR_4 PF12799.7 EGR27628.1 - 7.1e-08 32.6 22.3 0.029 14.8 0.3 5.2 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGR27628.1 - 8.6e-06 25.6 16.3 4.1 8.3 0.4 7.9 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.6 EGR27628.1 - 5.9 6.7 26.1 12 5.7 0.2 5.9 3 3 0 3 3 3 0 Leucine rich repeat PI-PLC-X PF00388.19 EGR27629.1 - 1.2e-61 206.5 0.4 1.2e-61 206.5 0.4 3.2 3 1 1 5 5 5 1 Phosphatidylinositol-specific phospholipase C, X domain EF-hand_1 PF00036.32 EGR27629.1 - 1.3e-08 33.8 10.3 1.3e-05 24.4 0.2 3.3 4 0 0 4 4 4 2 EF hand EF-hand_10 PF14788.6 EGR27629.1 - 2e-08 34.0 3.7 5e-08 32.7 2.4 2.5 2 1 1 3 3 3 1 EF hand EF-hand_6 PF13405.6 EGR27629.1 - 2.3e-08 33.3 1.3 0.00032 20.4 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EGR27629.1 - 2.5e-08 34.2 6.9 9.7e-06 25.9 0.5 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGR27629.1 - 0.0089 15.5 0.5 0.0089 15.5 0.5 2.0 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EGR27629.1 - 0.03 14.2 1.0 0.19 11.6 0.1 2.6 1 1 1 2 2 2 0 EF-hand domain pair Sec16_C PF12931.7 EGR27630.1 - 7.6e-07 29.1 0.0 3.3e-06 27.0 0.0 2.0 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.32 EGR27630.1 - 0.00019 22.2 1.3 3.1 8.8 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat PixA PF12306.8 EGR27630.1 - 0.23 11.6 3.5 7.4 6.7 0.0 3.6 4 0 0 4 4 4 0 Inclusion body protein SF-assemblin PF06705.11 EGR27632.1 - 1.2e-08 34.6 19.3 1.2e-08 34.6 19.3 2.3 1 1 1 2 2 2 1 SF-assemblin/beta giardin Tup_N PF08581.10 EGR27632.1 - 0.0035 17.6 1.7 0.0035 17.6 1.7 4.4 2 2 1 3 3 3 1 Tup N-terminal DUF3140 PF11338.8 EGR27632.1 - 0.13 12.7 2.6 0.14 12.6 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) FtsK_SpoIIIE PF01580.18 EGR27632.1 - 0.22 10.8 1.9 0.34 10.2 0.3 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family ApoO PF09769.9 EGR27632.1 - 1 9.3 6.4 2.2 8.3 0.3 2.9 2 1 0 3 3 3 0 Apolipoprotein O Baculo_PEP_C PF04513.12 EGR27632.1 - 7.7 6.6 14.6 1.4 9.0 1.6 3.4 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Glucokinase PF02685.16 EGR27633.1 - 1.8e-42 145.5 0.0 3.4e-42 144.5 0.0 1.4 1 1 0 1 1 1 1 Glucokinase HSR PF03172.13 EGR27633.1 - 0.088 13.0 0.6 0.27 11.4 0.2 2.1 2 0 0 2 2 2 0 HSR domain TTL PF03133.15 EGR27634.1 - 7.1e-69 232.2 4.6 7.1e-69 232.2 4.6 3.1 3 1 0 3 3 3 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 EGR27634.1 - 3.1e-06 26.6 0.2 0.0084 15.4 0.0 2.5 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 EGR27634.1 - 1.1e-05 24.9 0.1 1.1e-05 24.9 0.1 3.0 4 0 0 4 4 4 2 YheC/D like ATP-grasp Enolase_C PF00113.22 EGR27635.1 - 1.5e-149 497.1 0.3 1.9e-149 496.8 0.3 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EGR27635.1 - 4.9e-53 178.8 0.2 9.7e-53 177.8 0.2 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EGR27635.1 - 8.3e-08 32.1 0.0 1.7e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EGR27635.1 - 3.2e-05 23.2 0.1 6.6e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus SDA1 PF05285.12 EGR27637.1 - 1.4e-15 57.6 65.9 2e-15 57.1 0.2 3.6 1 1 2 3 3 3 2 SDA1 LRRC37AB_C PF14914.6 EGR27637.1 - 0.73 9.7 0.0 0.73 9.7 0.0 3.7 2 1 0 3 3 3 0 LRRC37A/B like protein 1 C-terminal domain FRQ PF09421.10 EGR27637.1 - 5.8 4.8 22.4 9 4.2 22.4 1.3 1 0 0 1 1 1 0 Frequency clock protein NUC130_3NT PF08158.12 EGR27638.1 - 3.8e-10 39.9 0.4 9.2e-10 38.7 0.4 1.7 1 0 0 1 1 1 1 NUC130/3NT domain Di19_C PF14571.6 EGR27638.1 - 4.6 7.8 8.0 9.3 6.9 0.9 2.4 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal Glyco_hydro_4C PF11975.8 EGR27638.1 - 6.4 6.8 9.2 10 6.1 9.2 1.7 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain IBR PF01485.21 EGR27639.1 - 1.3e-08 34.9 15.7 1.3e-08 34.9 15.7 4.6 3 1 1 4 4 4 1 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 EGR27639.1 - 0.016 15.2 5.6 0.016 15.2 5.6 3.0 3 1 0 3 3 3 0 RING-type zinc-finger PNK3P PF08645.11 EGR27639.1 - 0.016 14.9 3.0 0.041 13.6 3.0 1.7 1 0 0 1 1 1 0 Polynucleotide kinase 3 phosphatase DUF3217 PF11506.8 EGR27639.1 - 0.028 14.4 1.6 0.08 12.9 1.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3217) zf-FPG_IleRS PF06827.14 EGR27639.1 - 0.37 10.7 8.0 5.4 7.0 0.7 3.4 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS zf-C3HC4_2 PF13923.6 EGR27639.1 - 0.38 10.6 20.3 0.043 13.7 3.0 3.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGR27639.1 - 2.6 7.9 27.7 0.21 11.5 4.5 3.8 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Exo_endo_phos PF03372.23 EGR27641.1 - 1.3e-05 24.8 0.1 2.5e-05 23.9 0.1 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribosomal_60s PF00428.19 EGR27642.1 - 4.8e-21 75.1 11.9 5.8e-21 74.9 11.9 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein RQC PF09382.10 EGR27642.1 - 0.0071 16.1 0.0 0.0098 15.7 0.0 1.2 1 0 0 1 1 1 1 RQC domain DUF3391 PF11871.8 EGR27642.1 - 0.16 12.5 1.3 0.23 12.0 1.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF3391) Cytomega_UL84 PF06284.11 EGR27642.1 - 0.18 10.2 1.1 0.21 10.0 1.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein SGL PF08450.12 EGR27644.1 - 2.2e-09 37.2 0.0 3.3e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region NHL PF01436.21 EGR27644.1 - 8.5e-06 25.6 0.0 0.028 14.4 0.0 5.3 6 0 0 6 6 6 1 NHL repeat Str_synth PF03088.16 EGR27644.1 - 2.1e-05 24.5 0.0 0.00019 21.5 0.0 2.5 2 0 0 2 2 2 1 Strictosidine synthase Arylesterase PF01731.20 EGR27644.1 - 0.0017 18.5 0.0 2.1 8.6 0.0 2.9 3 0 0 3 3 3 2 Arylesterase RabGAP-TBC PF00566.18 EGR27645.1 - 1.1e-06 28.5 22.8 1.8e-05 24.5 22.8 3.1 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Glutaredoxin PF00462.24 EGR27647.1 - 1.8e-17 63.3 0.1 3.2e-17 62.5 0.1 1.4 1 0 0 1 1 1 1 Glutaredoxin Kinesin PF00225.23 EGR27647.1 - 0.014 14.3 2.3 0.02 13.8 2.3 1.2 1 0 0 1 1 1 0 Kinesin motor domain FANCI_S1-cap PF14674.6 EGR27647.1 - 0.017 15.2 0.1 0.71 10.0 0.0 2.8 3 0 0 3 3 3 0 FANCI solenoid 1 cap DUF2407_C PF13373.6 EGR27648.1 - 0.003 17.7 0.3 0.0036 17.5 0.3 1.1 1 0 0 1 1 1 1 DUF2407 C-terminal domain ThrE PF06738.12 EGR27648.1 - 0.0036 16.7 0.0 0.0041 16.5 0.0 1.2 1 0 0 1 1 1 1 Putative threonine/serine exporter CcdA PF07362.12 EGR27648.1 - 0.016 15.6 2.0 0.029 14.8 2.0 1.3 1 0 0 1 1 1 0 Post-segregation antitoxin CcdA Ribosomal_L37 PF08561.10 EGR27648.1 - 0.026 15.0 10.1 0.031 14.8 10.1 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 Gly-zipper_Omp PF13488.6 EGR27648.1 - 0.035 14.1 13.0 0.049 13.6 13.0 1.3 1 0 0 1 1 1 0 Glycine zipper DUF4199 PF13858.6 EGR27648.1 - 0.044 14.2 0.2 0.051 14.0 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) RNA_pol_Rbc25 PF08292.12 EGR27648.1 - 0.13 12.5 3.2 0.19 12.0 3.2 1.3 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 DUF456 PF04306.13 EGR27648.1 - 0.13 12.6 4.9 0.16 12.2 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF456) Synaptobrevin PF00957.21 EGR27648.1 - 0.14 11.9 5.3 0.18 11.6 5.3 1.2 1 0 0 1 1 1 0 Synaptobrevin Gly-zipper_YMGG PF13441.6 EGR27648.1 - 0.2 11.4 13.2 0.3 10.8 13.2 1.3 1 0 0 1 1 1 0 YMGG-like Gly-zipper PCRF PF03462.18 EGR27648.1 - 0.23 11.3 4.4 0.27 11.1 4.4 1.1 1 0 0 1 1 1 0 PCRF domain TMPIT PF07851.13 EGR27648.1 - 0.24 10.6 7.0 0.29 10.3 7.0 1.0 1 0 0 1 1 1 0 TMPIT-like protein ISG65-75 PF11727.8 EGR27648.1 - 0.99 8.6 7.0 1.1 8.4 7.0 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein Tup_N PF08581.10 EGR27648.1 - 1.1 9.6 13.5 1.4 9.3 13.5 1.2 1 0 0 1 1 1 0 Tup N-terminal Bacteriocin_IIc PF10439.9 EGR27648.1 - 1.2 9.4 12.5 1.8 8.7 12.5 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide DUF4407 PF14362.6 EGR27648.1 - 1.2 8.4 5.6 1.4 8.2 5.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4763 PF15960.5 EGR27648.1 - 1.8 7.8 12.6 1.9 7.7 12.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Sec20 PF03908.13 EGR27648.1 - 2 8.4 7.4 4 7.4 6.3 1.8 1 1 0 1 1 1 0 Sec20 Atg14 PF10186.9 EGR27648.1 - 2.4 7.1 9.9 2.9 6.9 9.9 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HemX PF04375.14 EGR27648.1 - 7.8 5.7 15.3 9.3 5.4 15.3 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase CHIPS PF11434.8 EGR27649.1 - 0.012 15.4 0.0 0.035 13.9 0.0 1.8 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS Ion_trans_2 PF07885.16 EGR27650.1 - 4.5e-11 42.6 3.7 6.4e-11 42.1 3.7 1.2 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGR27650.1 - 5.5e-10 38.9 2.6 8e-10 38.4 2.6 1.2 1 0 0 1 1 1 1 Ion transport protein DUF4618 PF15397.6 EGR27650.1 - 0.004 16.6 1.0 0.004 16.6 1.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4618) ZnuA PF01297.17 EGR27650.1 - 0.036 13.5 1.0 1.2 8.4 0.5 2.2 2 0 0 2 2 2 0 Zinc-uptake complex component A periplasmic TMF_TATA_bd PF12325.8 EGR27650.1 - 0.056 13.7 1.7 0.21 11.8 0.8 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Nbl1_Borealin_N PF10444.9 EGR27650.1 - 0.067 12.8 1.3 0.22 11.2 0.1 2.4 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal ZapA PF05164.13 EGR27650.1 - 0.073 13.5 1.4 0.13 12.7 0.5 1.8 2 0 0 2 2 2 0 Cell division protein ZapA DnaT PF17948.1 EGR27650.1 - 0.077 12.7 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 DnaT DNA-binding domain ADPrib_exo_Tox PF03496.14 EGR27650.1 - 0.078 12.3 5.1 0.12 11.7 0.4 2.1 2 0 0 2 2 2 0 ADP-ribosyltransferase exoenzyme CENP-Q PF13094.6 EGR27650.1 - 0.085 13.0 1.8 0.12 12.5 1.0 1.5 1 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Baculo_PEP_C PF04513.12 EGR27650.1 - 0.15 12.1 5.1 0.12 12.4 1.3 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus dCache_1 PF02743.18 EGR27650.1 - 0.51 10.1 5.8 15 5.3 0.2 3.2 1 1 2 3 3 3 0 Cache domain ABC2_membrane PF01061.24 EGR27651.1 - 3.7e-42 144.1 14.9 3.7e-42 144.1 14.9 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EGR27651.1 - 6.3e-23 81.8 0.6 6.3e-23 81.8 0.6 2.2 2 1 1 3 3 3 1 ABC transporter ABC2_membrane_3 PF12698.7 EGR27651.1 - 9.1e-10 38.2 17.8 9.1e-10 38.2 17.8 2.3 2 0 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EGR27651.1 - 3.1e-05 23.9 0.7 3.1e-05 23.9 0.7 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 EGR27651.1 - 0.00014 21.8 5.6 0.051 13.4 0.0 2.7 2 1 1 3 3 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGR27651.1 - 0.00044 20.7 0.0 0.0007 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EGR27651.1 - 0.00061 20.3 0.1 0.0021 18.6 0.1 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EGR27651.1 - 0.00099 19.5 0.1 0.066 13.6 0.0 3.0 2 0 0 2 2 2 1 RNA helicase ABC2_membrane_2 PF12679.7 EGR27651.1 - 0.0014 18.0 1.1 0.0014 18.0 1.1 1.9 1 1 1 2 2 2 1 ABC-2 family transporter protein Rad17 PF03215.15 EGR27651.1 - 0.0041 17.1 2.7 0.0044 16.9 0.5 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_30 PF13604.6 EGR27651.1 - 0.013 15.2 0.0 0.021 14.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 EGR27651.1 - 0.02 14.5 0.1 0.042 13.4 0.1 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EGR27651.1 - 0.024 14.7 0.1 0.068 13.3 0.1 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 EGR27651.1 - 0.03 14.6 0.0 0.097 12.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGR27651.1 - 0.036 13.1 1.5 0.075 12.1 1.5 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_28 PF13521.6 EGR27651.1 - 0.045 14.0 0.0 0.076 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF3236 PF11576.8 EGR27651.1 - 0.056 13.2 0.3 3.8 7.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3236) PRK PF00485.18 EGR27651.1 - 0.058 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_29 PF13555.6 EGR27651.1 - 0.061 13.1 1.5 0.2 11.4 1.5 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain PrgI PF12666.7 EGR27651.1 - 0.079 13.7 0.1 0.5 11.1 0.1 2.4 1 0 0 1 1 1 0 PrgI family protein ATPase_2 PF01637.18 EGR27651.1 - 3.9 7.3 8.5 0.13 12.2 0.6 2.3 2 2 0 2 2 2 0 ATPase domain predominantly from Archaea Cofilin_ADF PF00241.20 EGR27652.1 - 1.1e-27 96.3 0.3 1.3e-27 96.0 0.3 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein DUF2540 PF10802.8 EGR27652.1 - 0.0011 19.1 0.9 0.0012 18.9 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2540) hSH3 PF14603.6 EGR27652.1 - 0.0065 16.9 0.7 0.012 16.1 0.7 1.4 1 0 0 1 1 1 1 Helically-extended SH3 domain DUF2004 PF09406.10 EGR27652.1 - 0.092 13.1 0.1 0.15 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2004) RNA_pol_Rpb2_6 PF00562.28 EGR27654.1 - 2.4e-112 375.8 0.1 4e-112 375.1 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGR27654.1 - 9.8e-32 110.1 2.8 1.6e-31 109.4 2.8 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EGR27654.1 - 6.7e-27 94.4 4.8 1.5e-26 93.2 4.8 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EGR27654.1 - 2e-25 89.0 0.1 6.3e-25 87.4 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EGR27654.1 - 5.4e-22 77.7 0.1 1.1e-21 76.8 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 EGR27654.1 - 2.7e-20 72.4 0.1 8.7e-20 70.8 0.1 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 EGR27654.1 - 9e-12 45.4 0.1 3.2e-11 43.6 0.1 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 OrfB_Zn_ribbon PF07282.11 EGR27654.1 - 0.13 12.2 0.5 3.1 7.8 0.2 2.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Z1 PF10593.9 EGR27654.1 - 1.1 8.7 4.0 1.2 8.6 0.0 2.4 2 0 0 2 2 2 0 Z1 domain PDEase_I PF00233.19 EGR27655.1 - 7.8e-40 137.1 6.9 7.8e-40 137.1 6.9 1.5 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase adh_short PF00106.25 EGR27656.1 - 0.047 13.1 0.0 0.062 12.7 0.0 1.1 1 0 0 1 1 1 0 short chain dehydrogenase FOP_dimer PF09398.10 EGR27657.1 - 0.008 16.4 0.5 0.064 13.5 0.0 2.9 3 0 0 3 3 3 1 FOP N terminal dimerisation domain FPL PF09758.9 EGR27657.1 - 0.012 15.6 0.9 0.012 15.6 0.9 3.7 2 2 2 4 4 4 0 Uncharacterised conserved protein RICTOR_V PF14668.6 EGR27657.1 - 0.02 15.1 1.7 8.2 6.7 0.2 3.3 2 2 1 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 FtsK_SpoIIIE PF01580.18 EGR27657.1 - 0.08 12.3 0.5 0.19 11.0 0.1 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Nucleoporin_FG PF13634.6 EGR27658.1 - 0.0065 17.3 45.4 0.049 14.5 19.6 2.4 1 1 1 2 2 2 2 Nucleoporin FG repeat region TTL PF03133.15 EGR27659.1 - 2.3e-12 46.6 0.5 2.4e-12 46.6 0.5 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR27659.1 - 0.00064 19.1 0.0 0.00064 19.0 0.0 1.1 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR27659.1 - 0.001 18.4 0.0 0.0011 18.3 0.0 1.1 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp RimK PF08443.11 EGR27659.1 - 0.014 15.0 0.0 0.017 14.8 0.0 1.1 1 0 0 1 1 1 0 RimK-like ATP-grasp domain Clusterin PF01093.17 EGR27659.1 - 0.062 12.3 1.0 0.071 12.1 1.0 1.0 1 0 0 1 1 1 0 Clusterin Pkinase PF00069.25 EGR27661.1 - 1.3e-45 155.9 0.1 1.3e-45 155.9 0.1 1.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27661.1 - 3.7e-26 92.0 0.0 6.3e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 EGR27661.1 - 0.013 14.6 0.1 0.035 13.1 0.0 1.7 2 0 0 2 2 2 0 Seadornavirus VP7 APH PF01636.23 EGR27661.1 - 0.2 11.6 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family HD PF01966.22 EGR27663.1 - 2e-08 34.5 0.1 3.4e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 HD domain AdoHcyase PF05221.17 EGR27665.1 - 2.2e-137 457.2 0.0 2.5e-137 457.0 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EGR27665.1 - 2.6e-78 261.7 2.6 3.9e-78 261.1 2.6 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EGR27665.1 - 5e-10 39.0 0.2 1e-09 38.0 0.2 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EGR27665.1 - 0.0001 21.9 0.2 0.00018 21.2 0.2 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain NAD_binding_7 PF13241.6 EGR27665.1 - 0.00012 22.4 0.2 0.00033 21.0 0.2 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 EGR27665.1 - 0.0002 21.4 0.3 0.00049 20.2 0.3 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase THF_DHG_CYH_C PF02882.19 EGR27665.1 - 0.00092 18.6 1.2 0.0036 16.6 1.2 1.8 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.18 EGR27665.1 - 0.0088 16.3 0.5 0.043 14.1 0.5 2.1 1 1 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.21 EGR27665.1 - 0.025 14.3 0.1 0.044 13.5 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AlaDh_PNT_C PF01262.21 EGR27665.1 - 0.029 13.7 3.4 0.086 12.1 3.4 1.7 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EGR27665.1 - 0.19 11.6 0.6 0.44 10.4 0.7 1.6 1 1 1 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HECT PF00632.25 EGR27666.1 - 2e-72 244.3 7.4 2.2e-72 244.1 7.4 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Guanylate_cyc PF00211.20 EGR27667.1 - 3e-14 53.0 0.1 8.9e-14 51.5 0.1 1.8 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ion_trans PF00520.31 EGR27667.1 - 0.00015 21.1 0.4 0.00015 21.1 0.4 2.0 2 0 0 2 2 2 1 Ion transport protein Pkinase PF00069.25 EGR27668.1 - 1.7e-55 188.3 0.2 1.7e-55 188.3 0.2 2.0 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27668.1 - 1.6e-26 93.1 0.0 6.8e-26 91.1 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR27668.1 - 0.0037 16.6 1.9 0.076 12.4 0.1 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Aa_trans PF01490.18 EGR27669.1 - 5.9e-05 22.0 9.2 8.5e-05 21.4 9.2 1.2 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Orai-1 PF07856.12 EGR27669.1 - 0.047 13.4 1.1 0.069 12.8 1.1 1.2 1 0 0 1 1 1 0 Mediator of CRAC channel activity Vac14_Fab1_bd PF12755.7 EGR27670.1 - 0.015 15.8 3.4 0.35 11.5 0.1 3.5 3 0 0 3 3 3 0 Vacuolar 14 Fab1-binding region WD40 PF00400.32 EGR27673.1 - 1.6e-09 38.2 10.7 0.0014 19.4 0.0 4.9 3 2 1 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR27673.1 - 1.3e-08 35.0 0.7 1.9e-05 24.9 0.0 4.1 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGR27673.1 - 2.1e-05 24.5 0.2 0.24 11.2 0.2 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A IFT20 PF14931.6 EGR27673.1 - 0.15 12.2 0.5 0.94 9.7 0.0 2.2 3 0 0 3 3 3 0 Intraflagellar transport complex B, subunit 20 PIG-L PF02585.17 EGR27674.1 - 2.1e-17 64.0 0.0 2.8e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Kelch_1 PF01344.25 EGR27675.1 - 8.1e-32 108.6 3.2 9.9e-07 28.2 0.0 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 EGR27675.1 - 3.4e-28 97.3 0.1 4.6e-07 30.0 0.0 5.4 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EGR27675.1 - 2.6e-27 94.3 11.2 4.1e-07 29.8 0.0 5.4 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.6 EGR27675.1 - 4.4e-27 93.4 12.9 1.8e-06 28.0 0.0 5.7 4 2 1 5 5 5 5 Kelch motif Kelch_4 PF13418.6 EGR27675.1 - 1.3e-24 85.9 9.1 3.9e-07 30.0 0.0 5.4 5 0 0 5 5 5 5 Galactose oxidase, central domain BTB PF00651.31 EGR27675.1 - 3e-18 66.1 0.4 5.3e-18 65.3 0.4 1.4 1 0 0 1 1 1 1 BTB/POZ domain Kelch_2 PF07646.15 EGR27675.1 - 2.2e-17 62.3 11.1 0.00074 19.4 0.6 5.5 5 0 0 5 5 5 5 Kelch motif Dak1 PF02733.17 EGR27676.1 - 4.6e-93 311.5 0.1 5.6e-93 311.2 0.1 1.1 1 0 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EGR27676.1 - 7.1e-12 45.6 0.0 1.4e-11 44.7 0.0 1.4 1 0 0 1 1 1 1 DAK2 domain MFS_1 PF07690.16 EGR27677.1 - 4.3e-16 58.8 7.8 4.3e-16 58.8 7.8 1.7 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGR27677.1 - 2.4e-14 53.0 21.4 2.4e-12 46.5 21.4 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter CDC45 PF02724.14 EGR27678.1 - 0.84 7.8 46.9 1 7.6 46.9 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EGR27678.1 - 6.2 6.1 61.4 7.7 5.8 61.4 1.1 1 0 0 1 1 1 0 SDA1 Gti1_Pac2 PF09729.9 EGR27678.1 - 6.4 6.8 15.8 8.3 6.5 15.8 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family BUD22 PF09073.10 EGR27678.1 - 6.5 6.0 50.2 7.6 5.8 50.2 1.0 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 EGR27678.1 - 6.6 5.1 52.7 9.2 4.6 52.7 1.3 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 EGR27678.1 - 7.5 4.6 56.0 10 4.1 56.0 1.2 1 0 0 1 1 1 0 Nop14-like family PriCT_1 PF08708.11 EGR27679.1 - 0.11 12.2 0.1 0.21 11.3 0.1 1.6 1 1 0 1 1 1 0 Primase C terminal 1 (PriCT-1) Transport_MerF PF11431.8 EGR27679.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Membrane transport protein MerF CDP-OH_P_transf PF01066.21 EGR27680.1 - 6e-17 62.2 0.2 1.1e-16 61.4 0.2 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF983 PF06170.12 EGR27680.1 - 0.022 15.2 0.4 0.044 14.2 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF983) Asp PF00026.23 EGR27681.1 - 3e-14 53.2 3.7 5.5e-14 52.3 3.7 1.4 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGR27681.1 - 0.001 18.9 0.4 0.042 13.6 0.4 2.5 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal DUF5362 PF17319.2 EGR27681.1 - 0.017 15.0 0.2 0.031 14.1 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5362) TMEM154 PF15102.6 EGR27681.1 - 0.07 13.0 0.2 0.14 12.1 0.2 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF5527 PF17665.1 EGR27681.1 - 0.44 10.1 1.3 1.1 8.8 1.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5527) TTL PF03133.15 EGR27682.1 - 3.7e-78 262.6 6.5 5.4e-78 262.1 6.5 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR27682.1 - 3.2e-06 26.6 0.2 0.00048 19.4 0.0 3.1 1 1 2 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR27682.1 - 0.0005 19.4 0.5 0.14 11.4 0.0 3.2 3 1 1 4 4 4 2 Sugar-transfer associated ATP-grasp zf-TRAF PF02176.18 EGR27683.1 - 7.8e-08 32.9 34.4 3.7e-05 24.3 10.4 5.9 4 2 2 6 6 6 3 TRAF-type zinc finger Sina PF03145.16 EGR27683.1 - 1.8e-06 28.0 6.5 1.8e-06 28.0 6.5 4.4 1 1 2 4 4 4 2 Seven in absentia protein family zf-C3HC4_2 PF13923.6 EGR27683.1 - 7.2e-05 22.5 13.1 7.2e-05 22.5 13.1 4.5 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGR27683.1 - 0.0004 20.2 14.3 0.0004 20.2 14.3 5.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) eIF_4EBP PF05456.11 EGR27683.1 - 2.7 7.9 7.5 2 8.4 4.1 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Pkinase PF00069.25 EGR27684.1 - 7.3e-61 205.8 0.0 1.5e-60 204.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27684.1 - 2e-33 115.8 0.0 3.8e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 EGR27684.1 - 2.4e-33 114.1 0.0 9.7e-22 76.9 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 EGR27684.1 - 1.4e-05 24.6 0.0 4.4e-05 22.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Cupin_3 PF05899.12 EGR27684.1 - 0.13 12.0 0.4 0.58 9.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF861) CRM1_repeat_3 PF18787.1 EGR27685.1 - 0.11 12.6 2.3 23 5.2 0.1 3.8 3 0 0 3 3 3 0 CRM1 / Exportin repeat 3 DUF501 PF04417.12 EGR27685.1 - 3.1 7.6 5.1 0.52 10.1 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF501) KicB PF03882.14 EGR27687.1 - 0.0077 16.4 1.4 0.011 16.0 0.7 1.5 1 1 0 1 1 1 1 MukF winged-helix domain Syntaxin-6_N PF09177.11 EGR27687.1 - 0.011 16.2 4.2 0.011 16.2 4.2 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal GET2 PF08690.10 EGR27687.1 - 0.028 14.1 5.8 0.032 13.9 5.8 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 DUF4407 PF14362.6 EGR27687.1 - 0.49 9.7 6.5 0.75 9.1 6.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1151 PF06625.11 EGR27687.1 - 0.87 9.5 8.3 3.2 7.7 8.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1151) UPF0449 PF15136.6 EGR27687.1 - 1.5 9.3 7.3 0.59 10.6 4.8 1.7 1 1 0 1 1 1 0 Uncharacterised protein family UPF0449 DUF1497 PF07384.11 EGR27687.1 - 9.2 6.8 10.4 1.3 9.5 3.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1497) HU-CCDC81_euk_1 PF14908.6 EGR27688.1 - 2.5e-22 78.8 0.2 2.5e-22 78.8 0.2 6.1 7 0 0 7 7 7 2 CCDC81 eukaryotic HU domain 1 EF-hand_1 PF00036.32 EGR27688.1 - 4.1e-22 76.0 49.9 0.0008 18.8 0.2 11.9 12 0 0 12 12 12 7 EF hand EF-hand_6 PF13405.6 EGR27688.1 - 1.6e-21 74.4 58.2 0.00047 19.9 0.2 12.3 13 0 0 13 13 13 7 EF-hand domain EF-hand_7 PF13499.6 EGR27688.1 - 1.7e-21 76.4 55.7 3.1e-07 30.8 3.2 9.9 9 2 0 10 10 10 7 EF-hand domain pair HU-CCDC81_euk_2 PF18289.1 EGR27688.1 - 2.5e-14 53.2 4.2 3.4e-14 52.8 0.4 3.3 3 0 0 3 3 3 1 CCDC81 eukaryotic HU domain 2 EF-hand_5 PF13202.6 EGR27688.1 - 7.1e-11 41.1 39.2 0.0017 17.7 1.6 7.4 8 0 0 8 8 8 5 EF hand EF-hand_8 PF13833.6 EGR27688.1 - 2.4e-07 30.5 24.5 0.76 9.7 0.1 8.2 7 1 1 8 8 8 4 EF-hand domain pair Dockerin_1 PF00404.18 EGR27688.1 - 2.9 8.1 7.8 19 5.5 1.6 5.0 5 1 1 6 6 6 0 Dockerin type I domain Cons_hypoth95 PF03602.15 EGR27689.1 - 0.0035 17.0 0.5 0.0035 17.0 0.5 2.3 1 1 0 2 2 2 1 Conserved hypothetical protein 95 Ribosomal_L26 PF16906.5 EGR27689.1 - 0.13 12.8 4.7 2.8 8.5 4.7 2.7 1 1 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal Response_reg PF00072.24 EGR27690.1 - 4.1e-20 72.0 0.3 1.1e-19 70.7 0.1 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EGR27690.1 - 0.00019 21.4 0.2 0.00079 19.4 0.1 2.2 2 1 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Ephrin_rec_like PF07699.13 EGR27691.1 - 4.2e-07 29.6 45.7 0.0033 17.2 3.4 7.3 3 2 4 7 7 7 4 Putative ephrin-receptor like Antistasin PF02822.14 EGR27691.1 - 0.024 15.3 5.3 12 6.6 0.0 4.9 4 0 0 4 4 4 0 Antistasin family Ephrin_rec_like PF07699.13 EGR27692.1 - 0.012 15.4 3.6 0.012 15.4 3.6 7.0 2 2 4 6 6 6 0 Putative ephrin-receptor like DUF4333 PF14230.6 EGR27692.1 - 0.97 9.7 8.0 4.6 7.6 0.4 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4333) Ephrin_rec_like PF07699.13 EGR27693.1 - 0.033 14.0 1.2 0.033 14.0 1.2 7.3 3 2 4 7 7 7 0 Putative ephrin-receptor like Zn_ribbon_SprT PF17283.2 EGR27693.1 - 5.5 7.0 13.3 0.6 10.1 1.4 3.3 3 0 0 3 3 3 0 SprT-like zinc ribbon domain Ephrin_rec_like PF07699.13 EGR27694.1 - 0.015 15.1 51.4 0.045 13.5 0.9 7.5 2 2 6 8 8 8 0 Putative ephrin-receptor like Antistasin PF02822.14 EGR27694.1 - 0.44 11.2 0.1 0.44 11.2 0.1 6.2 7 0 0 7 7 7 0 Antistasin family Fucose_iso_N2 PF07882.12 EGR27695.1 - 0.93 9.0 8.4 0.024 14.2 1.4 2.0 2 1 0 2 2 2 0 L-fucose isomerase, second N-terminal domain HECT PF00632.25 EGR27696.1 - 7.3e-65 219.5 18.5 2e-52 178.6 11.3 3.5 3 1 1 4 4 4 3 HECT-domain (ubiquitin-transferase) Fimbrillin_C PF15495.6 EGR27696.1 - 0.035 14.5 0.3 0.1 13.0 0.3 1.8 1 0 0 1 1 1 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal DUF2547 PF10818.8 EGR27696.1 - 2.2 9.3 7.1 81 4.2 5.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) RNase_Zc3h12a PF11977.8 EGR27697.1 - 5.3e-10 39.3 5.6 2e-09 37.4 0.9 3.5 3 0 0 3 3 3 1 Zc3h12a-like Ribonuclease NYN domain EST1_DNA_bind PF10373.9 EGR27697.1 - 1e-07 31.8 15.8 1.9e-07 30.8 15.8 1.5 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain Flavokinase PF01687.17 EGR27698.1 - 5.9e-06 26.6 0.0 1.5e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Riboflavin kinase Hydrolase_6 PF13344.6 EGR27698.1 - 0.024 14.8 0.0 0.098 12.8 0.0 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Kinesin PF00225.23 EGR27700.1 - 1.3e-53 182.1 9.9 1.3e-53 182.1 9.9 2.6 3 1 0 3 3 3 1 Kinesin motor domain Peptidase_M15_2 PF05951.13 EGR27700.1 - 0.0046 16.6 0.4 0.0046 16.6 0.4 3.6 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF882) GPW_gp25 PF04965.14 EGR27700.1 - 0.0071 16.1 0.1 0.018 14.8 0.1 1.7 1 0 0 1 1 1 1 Gene 25-like lysozyme IL23 PF16649.5 EGR27700.1 - 5.4 7.0 8.2 12 5.9 5.4 2.6 2 0 0 2 2 2 0 Interleukin 23 subunit alpha Pkinase PF00069.25 EGR27701.1 - 1.2e-69 234.7 0.6 1.2e-69 234.7 0.6 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27701.1 - 9.4e-37 126.7 0.0 9.4e-37 126.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR27701.1 - 1.3e-05 24.1 3.2 3.1e-05 23.0 3.2 1.5 1 1 0 1 1 1 1 Fungal protein kinase Presenilin PF01080.17 EGR27701.1 - 4.1 6.1 11.0 6.5 5.4 11.0 1.3 1 0 0 1 1 1 0 Presenilin Asp PF00026.23 EGR27703.1 - 1.5e-28 100.2 9.6 8.5e-26 91.1 9.6 3.0 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGR27703.1 - 2.9e-21 76.5 2.5 2.9e-21 76.5 2.5 2.2 3 0 0 3 3 3 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGR27703.1 - 5.7e-08 32.7 0.0 1.2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Peptidase_M56 PF05569.11 EGR27703.1 - 0.0018 17.5 1.7 0.0029 16.8 1.7 1.3 1 0 0 1 1 1 1 BlaR1 peptidase M56 Comm PF15957.5 EGR27703.1 - 0.0067 16.8 0.1 0.019 15.3 0.0 1.8 1 1 0 1 1 1 1 Commissureless Orf78 PF06024.12 EGR27703.1 - 0.008 16.5 5.6 0.008 16.5 5.6 2.9 1 1 1 2 2 2 1 Orf78 (ac78) SUR7 PF06687.12 EGR27703.1 - 0.011 15.4 2.4 0.015 15.0 0.1 2.2 2 0 0 2 2 2 0 SUR7/PalI family Vma12 PF11712.8 EGR27703.1 - 0.069 13.2 2.0 0.25 11.4 1.4 2.2 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase CrgA PF06781.12 EGR27703.1 - 0.089 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 Cell division protein CrgA SLATT_5 PF18160.1 EGR27703.1 - 0.1 11.9 11.4 0.017 14.5 6.7 2.0 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 PI3_PI4_kinase PF00454.27 EGR27704.1 - 1.3e-49 169.3 6.9 3.7e-49 167.8 2.3 3.1 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGR27704.1 - 7.8e-34 116.7 0.4 2.7e-33 114.9 0.4 1.9 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 EGR27704.1 - 2.3e-18 66.4 0.2 7.4e-18 64.8 0.2 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 EGR27704.1 - 4.2e-08 33.3 1.5 1.3e-07 31.7 0.4 2.6 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain TraB PF01963.17 EGR27705.1 - 0.022 14.7 0.3 0.16 11.9 0.1 2.2 2 0 0 2 2 2 0 TraB family NAD_Gly3P_dh_N PF01210.23 EGR27705.1 - 0.1 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus FKBP_C PF00254.28 EGR27707.1 - 2.3e-17 63.1 0.0 2.7e-17 62.9 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PhoLip_ATPase_C PF16212.5 EGR27708.1 - 3.6e-43 148.1 5.6 3.6e-43 148.1 5.6 2.5 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGR27708.1 - 1.6e-22 79.0 9.3 3.4e-20 71.5 5.9 2.8 2 0 0 2 2 2 2 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGR27708.1 - 1.1e-11 44.7 0.2 9e-11 41.7 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGR27708.1 - 3.3e-11 43.9 0.6 0.0017 18.7 0.1 3.3 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGR27708.1 - 3.2e-05 23.5 0.0 7.9e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase DUF1298 PF06974.13 EGR27708.1 - 0.052 13.5 0.1 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1298) TruD PF01142.18 EGR27709.1 - 2.8e-65 220.8 15.8 4.1e-63 213.6 10.5 3.1 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Stealth_CR4 PF17103.5 EGR27709.1 - 0.02 14.7 0.1 0.1 12.5 0.1 2.2 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 PP2C PF00481.21 EGR27710.1 - 2.1e-42 145.5 0.2 1.9e-41 142.4 0.0 2.3 2 1 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGR27710.1 - 0.05 13.2 0.0 0.089 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein phosphatase 2C Cpn60_TCP1 PF00118.24 EGR27711.1 - 3.9e-158 527.1 4.8 4.9e-158 526.8 4.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Kinesin PF00225.23 EGR27712.1 - 8e-79 265.0 3.5 1.1e-78 264.5 3.5 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR27712.1 - 0.00015 21.7 1.7 0.00068 19.6 0.0 2.3 2 0 0 2 2 2 1 Microtubule binding Thoc2 PF11732.8 EGR27713.1 - 0.084 13.0 1.3 0.19 11.8 0.2 2.1 1 1 1 2 2 2 0 Transcription- and export-related complex subunit Methyltransf_25 PF13649.6 EGR27714.1 - 1.7e-12 47.9 0.0 6.6e-07 30.0 0.0 3.1 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 EGR27714.1 - 4.8e-12 45.9 14.4 4.2e-08 33.1 0.1 4.0 3 1 1 4 4 4 2 Methyltransferase domain Methyltransf_11 PF08241.12 EGR27714.1 - 4.4e-11 43.3 0.0 8.8e-07 29.5 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EGR27714.1 - 7.4e-09 35.7 0.4 0.015 15.1 0.0 3.4 3 1 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 EGR27714.1 - 7.7e-08 33.0 2.1 0.02 15.6 0.0 3.7 4 0 0 4 4 4 2 Methyltransferase domain Spermine_synth PF01564.17 EGR27714.1 - 0.0026 17.2 4.9 0.0035 16.8 2.9 2.3 2 1 0 2 2 2 1 Spermine/spermidine synthase domain Methyltransf_2 PF00891.18 EGR27714.1 - 0.0033 16.8 0.1 0.0097 15.2 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase domain MTS PF05175.14 EGR27714.1 - 0.0093 15.5 0.0 3.2 7.3 0.0 2.7 2 0 0 2 2 2 2 Methyltransferase small domain HAD PF12710.7 EGR27715.1 - 0.17 12.3 0.0 0.24 11.8 0.0 1.2 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase FAD_binding_1 PF00667.20 EGR27716.1 - 3.6e-28 98.6 2.1 4.5e-28 98.3 0.6 1.8 2 0 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.21 EGR27716.1 - 1.9e-13 51.0 0.0 6.1e-13 49.4 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain SH3_5 PF08460.10 EGR27716.1 - 0.016 15.3 1.3 0.39 10.8 0.0 2.8 3 0 0 3 3 3 0 Bacterial SH3 domain ketoacyl-synt PF00109.26 EGR27717.1 - 1.4e-42 146.1 0.0 2.7e-42 145.1 0.0 1.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGR27717.1 - 1.3e-28 99.4 0.0 2.2e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGR27717.1 - 0.00089 18.7 0.1 0.0023 17.3 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 EGR27717.1 - 0.036 14.5 0.4 0.16 12.4 0.1 2.1 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension AAA_6 PF12774.7 EGR27719.1 - 2.1e-150 500.2 0.4 4.2e-148 492.6 0.0 3.9 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGR27719.1 - 3.3e-113 378.8 26.2 3.3e-113 378.8 26.2 6.4 7 2 0 7 7 4 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 EGR27719.1 - 5.7e-111 370.6 0.8 5.7e-111 370.6 0.8 2.8 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EGR27719.1 - 6.2e-90 301.0 3.2 3e-89 298.8 1.7 3.1 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EGR27719.1 - 5.5e-69 231.7 10.0 5.5e-69 231.7 10.0 4.7 5 0 0 5 5 4 2 ATP-binding dynein motor region AAA_7 PF12775.7 EGR27719.1 - 7.1e-68 227.7 1.4 3e-62 209.3 0.1 3.9 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGR27719.1 - 1.7e-57 193.8 3.1 1.7e-57 193.8 3.1 3.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 EGR27719.1 - 2.4e-49 168.2 13.6 9.5e-49 166.3 13.6 2.1 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EGR27719.1 - 1.8e-42 144.2 0.0 2.3e-40 137.4 0.0 3.5 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EGR27719.1 - 2.2e-17 63.4 2.6 6.3e-17 61.9 0.5 3.2 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EGR27719.1 - 2.1e-16 60.0 4.0 6e-16 58.5 0.2 3.9 3 0 0 3 3 3 1 AAA+ lid domain AAA_5 PF07728.14 EGR27719.1 - 3.7e-13 49.6 0.0 0.00052 20.0 0.0 7.2 6 1 0 6 6 5 2 AAA domain (dynein-related subfamily) AAA PF00004.29 EGR27719.1 - 7.5e-08 32.9 2.9 0.37 11.2 0.0 5.5 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGR27719.1 - 7.8e-07 29.5 3.0 0.22 11.9 0.1 5.5 4 0 0 4 4 3 2 RNA helicase AAA_16 PF13191.6 EGR27719.1 - 3.8e-06 27.4 0.8 0.1 12.9 0.3 4.0 3 0 0 3 3 3 2 AAA ATPase domain T2SSE PF00437.20 EGR27719.1 - 3.4e-05 23.1 1.4 0.0016 17.5 0.1 3.2 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_22 PF13401.6 EGR27719.1 - 0.00019 21.7 3.8 7.1 6.9 0.1 5.3 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.6 EGR27719.1 - 0.00044 20.8 5.1 2 9.0 0.0 6.0 5 0 0 5 5 4 1 AAA domain FtsK_SpoIIIE PF01580.18 EGR27719.1 - 0.00082 18.8 0.1 0.0079 15.6 0.0 2.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family MMR_HSR1 PF01926.23 EGR27719.1 - 0.00095 19.2 0.0 0.00095 19.2 0.0 2.9 3 0 0 3 3 1 1 50S ribosome-binding GTPase AAA_30 PF13604.6 EGR27719.1 - 0.0012 18.6 0.1 2.5 7.8 0.1 3.3 3 0 0 3 3 3 1 AAA domain SRP54 PF00448.22 EGR27719.1 - 0.0018 17.9 1.3 1.2 8.7 0.0 3.9 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 EGR27719.1 - 0.016 15.1 0.1 0.64 9.9 0.0 3.5 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 EGR27719.1 - 0.016 14.9 0.2 0.57 10.0 0.0 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_28 PF13521.6 EGR27719.1 - 0.022 15.0 0.5 3.5 7.8 0.0 3.0 3 0 0 3 3 2 0 AAA domain Mg_chelatase PF01078.21 EGR27719.1 - 0.05 13.0 0.3 2.9 7.2 0.0 3.2 4 0 0 4 4 3 0 Magnesium chelatase, subunit ChlI Roc PF08477.13 EGR27719.1 - 0.06 13.6 12.5 0.2 11.9 0.3 4.7 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase DUF853 PF05872.12 EGR27719.1 - 0.16 10.5 6.5 14 4.2 0.0 4.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF853) N-SET PF11764.8 EGR27719.1 - 0.88 9.6 7.5 5 7.2 1.7 3.6 2 0 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component N ATPase PF06745.13 EGR27719.1 - 8.8 5.6 10.1 0.3 10.4 0.0 3.5 3 0 0 3 3 3 0 KaiC CbiA PF01656.23 EGR27719.1 - 9.8 6.2 8.7 6.5 6.8 0.0 4.7 5 0 0 5 5 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain Rieske PF00355.26 EGR27720.1 - 9.9e-11 41.4 0.0 2.1e-10 40.4 0.0 1.6 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain Pkinase PF00069.25 EGR27721.1 - 1.7e-66 224.3 0.1 1.7e-66 224.3 0.1 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27721.1 - 5.6e-50 170.0 0.0 1.4e-49 168.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27721.1 - 7.1e-07 28.8 7.8 1.1e-06 28.2 0.0 2.9 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 EGR27721.1 - 3.6e-05 22.7 0.0 3.6e-05 22.7 0.0 3.1 2 1 0 2 2 2 1 Fungal protein kinase Kinesin PF00225.23 EGR27722.1 - 1.3e-110 369.5 7.9 2e-110 368.9 7.9 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR27722.1 - 8.2e-28 97.2 5.4 8.2e-28 97.2 5.4 2.4 2 1 1 3 3 3 1 Microtubule binding AAA_16 PF13191.6 EGR27722.1 - 0.063 13.7 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGR27722.1 - 0.092 13.0 0.8 0.35 11.1 0.1 2.4 2 1 0 2 2 2 0 AAA domain WD40 PF00400.32 EGR27724.1 - 2e-07 31.6 0.1 1.1 10.2 0.0 5.9 7 0 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR27724.1 - 0.0011 19.2 1.9 0.56 10.5 0.1 4.9 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Metallophos PF00149.28 EGR27725.1 - 2.9e-32 112.8 0.1 3.8e-32 112.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGR27725.1 - 0.022 15.2 0.3 0.048 14.1 0.3 1.5 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Ras PF00071.22 EGR27726.1 - 2.4e-39 134.5 3.5 2.7e-39 134.4 3.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR27726.1 - 7.6e-26 90.7 0.4 1.2e-25 90.1 0.4 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR27726.1 - 6e-18 64.9 0.6 7.1e-18 64.7 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGR27726.1 - 1.1e-10 41.3 3.0 1.3e-10 41.0 3.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGR27726.1 - 0.00034 20.2 0.1 0.00042 19.9 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EGR27726.1 - 0.035 13.9 1.5 0.15 11.8 1.5 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 EGR27726.1 - 0.1 11.8 5.7 0.86 8.7 5.7 2.6 1 1 0 1 1 1 0 G-protein alpha subunit AAA_22 PF13401.6 EGR27726.1 - 0.1 12.8 0.1 1.7 8.9 0.1 2.2 1 1 0 1 1 1 0 AAA domain CENP-T_C PF15511.6 EGR27728.1 - 4e-08 33.3 0.1 5.1e-08 33.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EGR27728.1 - 6.4e-06 26.6 0.7 8.6e-06 26.1 0.7 1.2 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EGR27728.1 - 8.6e-05 22.6 0.3 0.00012 22.2 0.3 1.3 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 EGR27728.1 - 0.00014 22.2 0.2 0.00018 21.8 0.2 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EGR27728.1 - 0.00083 19.6 0.2 0.0012 19.1 0.2 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_L27A PF00828.19 EGR27728.1 - 0.0055 17.4 1.2 0.0071 17.0 1.2 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A TFIID-31kDa PF02291.15 EGR27728.1 - 0.022 14.8 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGR27728.1 - 0.029 14.4 0.1 0.048 13.7 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 EGR27729.1 - 7.8e-51 171.9 2.8 8.6e-51 171.7 2.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 EGR27729.1 - 0.0002 21.9 2.2 0.00026 21.6 2.2 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EGR27729.1 - 0.00024 21.2 0.8 0.0003 20.9 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGR27729.1 - 0.0023 18.3 0.0 0.0035 17.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EGR27729.1 - 0.062 13.4 0.1 0.12 12.4 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit TMA7 PF09072.10 EGR27729.1 - 0.068 14.0 3.3 0.12 13.2 3.3 1.4 1 0 0 1 1 1 0 Translation machinery associated TMA7 Glutaredoxin PF00462.24 EGR27730.1 - 6.4e-20 71.1 0.1 8.3e-20 70.8 0.1 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 EGR27730.1 - 5.1e-05 23.2 0.0 8.2e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.14 EGR27730.1 - 0.00057 20.2 0.0 0.00064 20.1 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) GST_N_3 PF13417.6 EGR27730.1 - 0.01 16.2 0.0 0.012 16.0 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF953 PF06110.11 EGR27730.1 - 0.026 14.1 0.3 0.036 13.7 0.3 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_7 PF13899.6 EGR27730.1 - 0.15 12.2 0.6 0.85 9.8 0.6 1.9 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_2 PF13098.6 EGR27730.1 - 0.17 12.4 0.6 0.36 11.3 0.6 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain DUF1462 PF07315.11 EGR27730.1 - 0.24 11.7 4.4 1.1 9.6 4.4 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1462) MIG-14_Wnt-bd PF06664.12 EGR27731.1 - 1.6e-18 67.0 8.9 2.3e-18 66.4 8.9 1.4 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion Nramp PF01566.18 EGR27733.1 - 1.1e-71 241.7 0.7 1.1e-71 241.7 0.7 1.9 1 1 1 2 2 2 1 Natural resistance-associated macrophage protein LapA_dom PF06305.11 EGR27733.1 - 1.4 8.8 6.9 7.9 6.4 0.3 2.8 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF485 PF04341.12 EGR27733.1 - 8.8 6.4 10.2 0.4 10.7 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function, DUF485 Pkinase PF00069.25 EGR27734.1 - 2.5e-61 207.4 0.2 2.9e-61 207.2 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27734.1 - 9.1e-19 67.7 0.0 1.2e-18 67.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR27734.1 - 4.8e-07 30.0 0.0 9.8e-07 28.9 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGR27734.1 - 0.0023 17.3 0.0 0.0035 16.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF1679 PF07914.11 EGR27734.1 - 0.0098 14.8 0.1 0.12 11.2 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1679) Choline_kinase PF01633.20 EGR27734.1 - 0.036 13.7 0.1 0.085 12.4 0.1 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase CUE PF02845.16 EGR27734.1 - 0.09 12.5 0.0 0.37 10.6 0.0 2.0 2 0 0 2 2 2 0 CUE domain RIH_assoc PF08454.11 EGR27735.1 - 5.8e-28 96.7 1.0 5.8e-28 96.7 1.0 12.4 14 3 1 15 15 15 1 RyR and IP3R Homology associated Ins145_P3_rec PF08709.11 EGR27735.1 - 2.5e-10 39.9 20.0 8.9e-09 34.9 12.6 4.3 2 1 1 3 3 3 2 Inositol 1,4,5-trisphosphate/ryanodine receptor RYDR_ITPR PF01365.21 EGR27735.1 - 6.5e-06 25.7 11.5 6.5e-06 25.7 11.5 7.6 5 3 0 6 6 6 2 RIH domain Ion_trans PF00520.31 EGR27735.1 - 5.5e-05 22.5 19.1 0.00017 20.9 19.1 2.0 1 1 0 1 1 1 1 Ion transport protein PTPRCAP PF15713.5 EGR27736.1 - 7.9 6.8 8.9 8.4 6.7 8.9 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Mrr_N PF14338.6 EGR27737.1 - 0.052 13.7 0.6 0.06 13.5 0.6 1.2 1 0 0 1 1 1 0 Mrr N-terminal domain UCH PF00443.29 EGR27738.1 - 6e-48 163.6 15.8 6e-48 163.6 15.8 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR27738.1 - 2.3e-17 63.6 18.4 2.3e-17 63.6 18.4 1.8 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EGR27738.1 - 7.3e-11 42.5 1.8 7.3e-11 42.5 1.8 4.1 1 1 2 3 3 3 1 DUSP domain Tudor-knot PF11717.8 EGR27738.1 - 0.057 13.3 3.7 0.081 12.8 0.2 2.5 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain zf-HIT PF04438.16 EGR27738.1 - 1.4 8.9 8.7 3 7.8 0.3 3.5 3 0 0 3 3 3 0 HIT zinc finger Fe-S_biosyn PF01521.20 EGR27739.1 - 3.6e-19 69.0 0.2 4.8e-19 68.6 0.2 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis ATP-synt_F PF01990.17 EGR27739.1 - 0.014 15.7 0.2 3.8 7.9 0.1 2.1 1 1 1 2 2 2 0 ATP synthase (F/14-kDa) subunit DUF3853 PF12964.7 EGR27739.1 - 0.07 13.3 0.4 0.11 12.7 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3853) ER_lumen_recept PF00810.18 EGR27740.1 - 2.8e-27 96.4 7.8 2.8e-27 96.4 7.8 2.0 1 1 1 2 2 2 1 ER lumen protein retaining receptor DUF1765 PF08578.10 EGR27741.1 - 7.9e-24 84.5 10.8 7.9e-24 84.5 10.8 3.8 4 1 0 4 4 4 1 Protein of unknown function (DUF1765) NUC130_3NT PF08158.12 EGR27741.1 - 0.038 14.3 1.0 0.14 12.5 0.2 2.3 2 0 0 2 2 2 0 NUC130/3NT domain DDE_2 PF02914.15 EGR27742.1 - 0.052 13.3 0.0 0.087 12.5 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage Mu transposase Histone_H2A_C PF16211.5 EGR27743.1 - 9.2e-18 63.7 0.4 1.7e-17 62.8 0.4 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGR27743.1 - 7.6e-15 55.4 0.0 1e-14 55.0 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGR27743.1 - 3.9e-06 27.0 0.0 6.4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YihI PF04220.12 EGR27743.1 - 0.097 12.4 0.1 0.16 11.7 0.1 1.5 1 1 0 1 1 1 0 Der GTPase activator (YihI) Ras PF00071.22 EGR27744.1 - 1.1e-55 187.6 1.9 1.6e-55 187.1 1.9 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR27744.1 - 2.4e-31 108.4 0.3 2.4e-31 108.4 0.3 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR27744.1 - 1.2e-16 60.6 0.7 1.7e-16 60.2 0.7 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGR27744.1 - 7.4e-07 28.8 0.4 9.8e-07 28.3 0.4 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGR27744.1 - 4.3e-06 26.4 1.5 6.5e-05 22.6 1.4 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGR27744.1 - 9.8e-05 21.9 0.0 0.00017 21.1 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGR27744.1 - 0.0086 16.2 0.1 0.012 15.7 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGR27744.1 - 0.023 13.9 4.1 2.3 7.3 1.6 2.6 1 1 1 2 2 2 0 G-protein alpha subunit AAA_14 PF13173.6 EGR27744.1 - 0.027 14.5 0.4 0.14 12.2 0.2 2.3 1 1 1 2 2 2 0 AAA domain DAP3 PF10236.9 EGR27744.1 - 0.029 13.5 0.1 0.06 12.5 0.0 1.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Ependymin PF00811.18 EGR27744.1 - 0.03 14.6 0.5 0.069 13.4 0.1 1.9 1 1 1 2 2 2 0 Ependymin RsgA_GTPase PF03193.16 EGR27744.1 - 0.033 14.1 0.2 0.24 11.3 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase FeoB_N PF02421.18 EGR27744.1 - 0.073 12.6 0.7 0.88 9.1 0.0 2.4 2 1 1 3 3 3 0 Ferrous iron transport protein B z-alpha PF02295.17 EGR27745.1 - 0.14 12.3 0.9 0.87 9.7 0.2 2.2 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain TCR_zetazeta PF11628.8 EGR27745.1 - 0.49 10.1 2.3 0.88 9.3 2.3 1.4 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 zeta chain CLP1_P PF16575.5 EGR27746.1 - 0.11 12.3 3.1 0.15 11.8 3.1 1.1 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Cadherin_tail PF15974.5 EGR27746.1 - 2.7 8.3 8.1 3.8 7.8 8.1 1.2 1 0 0 1 1 1 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region CBFD_NFYB_HMF PF00808.23 EGR27747.1 - 0.06 13.6 6.8 0.91 9.9 0.2 4.4 3 0 0 3 3 3 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2428 PF10350.9 EGR27747.1 - 0.065 12.5 2.2 0.13 11.5 2.2 1.4 1 0 0 1 1 1 0 Putative death-receptor fusion protein (DUF2428) DUF3710 PF12502.8 EGR27747.1 - 0.55 9.9 6.0 3.7 7.2 0.2 4.2 3 2 2 5 5 5 0 Protein of unknown function (DUF3710) SAM_adeno_trans PF01887.16 EGR27747.1 - 3.8 6.9 28.0 3.3 7.1 0.2 7.1 3 2 2 6 6 6 0 S-adenosyl-l-methionine hydroxide adenosyltransferase Zip PF02535.22 EGR27748.1 - 0.0092 15.2 1.4 0.022 14.0 1.4 1.6 1 1 0 1 1 1 1 ZIP Zinc transporter SRP19 PF01922.17 EGR27749.1 - 3.7e-29 101.5 0.8 4.8e-29 101.2 0.8 1.1 1 0 0 1 1 1 1 SRP19 protein POTRA_1 PF08478.10 EGR27749.1 - 0.05 13.9 0.1 0.1 12.9 0.1 1.5 1 0 0 1 1 1 0 POTRA domain, FtsQ-type NAP PF00956.18 EGR27750.1 - 2.2e-50 171.3 15.5 2.2e-50 171.3 15.5 1.8 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) A_deamin PF02137.18 EGR27750.1 - 0.032 13.7 0.1 0.032 13.7 0.1 1.5 2 0 0 2 2 2 0 Adenosine-deaminase (editase) domain Kinesin PF00225.23 EGR27751.1 - 3e-105 351.8 8.5 4.5e-105 351.3 8.5 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR27751.1 - 3.2e-25 88.8 6.8 8.2e-25 87.5 6.8 1.7 1 0 0 1 1 1 1 Microtubule binding IstB_IS21 PF01695.17 EGR27751.1 - 0.00046 20.0 0.0 0.0014 18.4 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 EGR27751.1 - 0.1 12.9 0.2 0.29 11.4 0.2 1.9 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGR27751.1 - 1.1 9.7 5.6 0.57 10.6 0.3 3.1 2 2 0 2 2 2 0 RNA helicase ResIII PF04851.15 EGR27751.1 - 6.5 6.7 18.4 0.09 12.8 6.2 2.9 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit DUF3149 PF11346.8 EGR27752.1 - 0.018 14.6 1.3 0.018 14.6 1.3 3.8 5 0 0 5 5 5 0 Protein of unknown function (DUF3149) Metallophos PF00149.28 EGR27753.1 - 1.1e-30 107.7 0.3 1.3e-30 107.4 0.3 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGR27753.1 - 0.11 12.7 0.0 0.15 12.3 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain LSM PF01423.22 EGR27754.1 - 1.7e-16 59.7 0.3 2.3e-16 59.3 0.3 1.2 1 0 0 1 1 1 1 LSM domain HECT PF00632.25 EGR27757.1 - 5.4e-86 288.9 5.5 1e-85 287.9 5.5 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) BUD22 PF09073.10 EGR27757.1 - 0.0065 15.9 43.6 0.014 14.7 43.6 1.5 1 0 0 1 1 1 1 BUD22 Chromosome_seg PF13889.6 EGR27758.1 - 0.036 14.2 0.2 0.1 12.8 0.2 1.7 1 0 0 1 1 1 0 Chromosome segregation during meiosis Thioredoxin PF00085.20 EGR27759.1 - 1.3e-20 73.3 0.1 1e-19 70.4 0.1 2.2 2 0 0 2 2 2 1 Thioredoxin TPR_20 PF14561.6 EGR27759.1 - 1.1e-08 35.3 0.3 3.4e-08 33.7 0.1 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat Thioredoxin_8 PF13905.6 EGR27759.1 - 0.00019 21.7 8.0 0.0046 17.3 0.0 3.8 2 2 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EGR27759.1 - 0.0011 19.4 2.7 0.011 16.2 0.4 3.0 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EGR27759.1 - 0.0089 16.1 0.0 0.026 14.6 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_7 PF13899.6 EGR27759.1 - 0.0089 16.2 0.0 0.02 15.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EGR27759.1 - 0.021 14.7 0.0 0.057 13.3 0.0 1.7 1 0 0 1 1 1 0 AhpC/TSA family TraF PF13728.6 EGR27759.1 - 0.054 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 F plasmid transfer operon protein Histone PF00125.24 EGR27760.1 - 1.8e-51 173.9 2.8 2e-51 173.7 2.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 EGR27760.1 - 0.00013 22.6 1.6 0.00016 22.2 1.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EGR27760.1 - 0.00038 20.5 0.9 0.00045 20.3 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGR27760.1 - 0.00099 19.4 0.0 0.0015 18.9 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EGR27760.1 - 0.042 13.9 0.1 0.083 13.0 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit TMA7 PF09072.10 EGR27760.1 - 0.067 14.0 3.3 0.12 13.2 3.3 1.4 1 0 0 1 1 1 0 Translation machinery associated TMA7 CENP-T_C PF15511.6 EGR27761.1 - 1.4e-09 38.0 0.2 1.7e-09 37.7 0.2 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EGR27761.1 - 9.3e-05 22.8 0.6 0.00015 22.1 0.7 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EGR27761.1 - 0.00019 21.5 0.2 0.00028 21.0 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EGR27761.1 - 0.00023 21.4 0.1 0.00037 20.7 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EGR27761.1 - 0.00026 21.3 0.3 0.00036 20.8 0.3 1.4 1 1 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.13 EGR27761.1 - 0.00082 19.3 0.1 0.0015 18.5 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 EGR27761.1 - 0.0043 17.1 0.0 0.0048 17.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Ribosomal_L27A PF00828.19 EGR27761.1 - 0.028 15.1 3.0 0.035 14.8 3.0 1.3 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A TAF4 PF05236.14 EGR27761.1 - 0.077 12.7 0.1 0.089 12.5 0.1 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF364 PF04016.12 EGR27761.1 - 0.089 12.4 0.0 0.12 11.9 0.0 1.3 1 1 0 1 1 1 0 Putative heavy-metal chelation Pkinase PF00069.25 EGR27762.1 - 3.9e-65 219.8 0.9 3.9e-65 219.8 0.9 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27762.1 - 5.6e-42 143.8 0.1 5.6e-42 143.8 0.1 2.5 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.23 EGR27762.1 - 0.17 11.7 0.0 0.47 10.3 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF775 PF05603.12 EGR27762.1 - 4.2 6.9 10.5 0.41 10.1 5.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF775) HMG-CoA_red PF00368.18 EGR27763.1 - 2.7e-105 352.4 0.3 3.6e-105 352.0 0.3 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase NYD-SP28 PF14772.6 EGR27764.1 - 2.5e-10 40.3 13.9 2.5e-10 40.3 13.9 5.7 2 1 3 5 5 5 1 Sperm tail NYD-SP28_assoc PF14775.6 EGR27764.1 - 2.8e-06 27.3 7.1 2.8e-06 27.3 7.1 4.5 4 1 0 4 4 4 1 Sperm tail C-terminal domain HAD_SAK_2 PF18143.1 EGR27764.1 - 3.3 8.0 8.1 0.41 10.9 0.9 2.7 3 0 0 3 3 3 0 HAD domain in Swiss Army Knife RNA repair proteins cNMP_binding PF00027.29 EGR27765.1 - 2e-14 53.4 0.1 5.5e-10 39.2 0.0 2.4 1 1 1 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 EGR27766.1 - 2.4e-49 168.1 0.1 2.9e-49 167.8 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27766.1 - 2.6e-35 122.0 0.1 2.9e-35 121.8 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27766.1 - 1.4e-07 31.1 0.0 1.6e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGR27766.1 - 2.4e-05 23.5 0.0 3e-05 23.1 0.0 1.0 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGR27766.1 - 0.0026 17.1 0.0 0.0031 16.9 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EGR27766.1 - 0.0093 15.1 0.0 0.012 14.7 0.0 1.1 1 0 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EGR27766.1 - 0.011 14.6 0.0 0.014 14.2 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 EGR27766.1 - 0.014 15.0 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 U-box PF04564.15 EGR27767.1 - 2.2e-16 59.8 2.8 2.7e-16 59.5 0.0 2.4 3 0 0 3 3 3 1 U-box domain TPR_1 PF00515.28 EGR27767.1 - 2.1e-10 39.9 10.7 1e-05 25.1 0.3 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGR27767.1 - 7.3e-10 38.2 1.0 0.00077 19.4 0.1 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGR27767.1 - 1.2e-08 34.5 1.3 1.9e-05 24.2 1.1 2.7 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.6 EGR27767.1 - 4.6e-06 26.4 6.1 0.018 15.2 0.1 3.3 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGR27767.1 - 7e-06 26.1 3.8 0.013 15.8 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR27767.1 - 0.00081 19.6 1.4 0.00081 19.6 1.4 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 zf-NOSIP PF15906.5 EGR27767.1 - 0.0033 17.5 0.1 0.01 16.0 0.1 1.8 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein TPR_12 PF13424.6 EGR27767.1 - 0.0036 17.6 0.2 0.018 15.3 0.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat zf-Nse PF11789.8 EGR27767.1 - 0.008 16.0 0.1 0.046 13.6 0.0 2.3 2 1 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit TPR_7 PF13176.6 EGR27767.1 - 0.0088 16.0 0.3 0.054 13.5 0.0 2.5 3 0 0 3 3 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGR27767.1 - 0.051 14.2 0.0 0.091 13.4 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C3HC4_4 PF15227.6 EGR27767.1 - 0.087 13.0 0.3 0.31 11.2 0.0 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EGR27767.1 - 0.13 12.3 0.0 0.48 10.5 0.0 2.0 2 0 0 2 2 2 0 RING-type zinc-finger MIT PF04212.18 EGR27767.1 - 0.19 11.8 0.4 0.19 11.8 0.4 3.6 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain ARD PF03079.14 EGR27767.1 - 5.5 7.2 9.6 1.1 9.4 2.3 2.2 2 0 0 2 2 2 0 ARD/ARD' family RRM_1 PF00076.22 EGR27768.1 - 4.2e-11 42.5 0.3 8.2e-11 41.6 0.3 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGR27768.1 - 0.00018 21.6 0.4 0.0021 18.2 0.0 2.3 1 1 1 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 EGR27768.1 - 0.011 15.3 0.0 0.02 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Leg1 PF05612.12 EGR27768.1 - 0.043 13.0 0.6 0.19 10.8 0.0 1.9 2 0 0 2 2 2 0 Leg1 LRR_4 PF12799.7 EGR27769.1 - 0.00019 21.7 34.8 0.018 15.5 0.3 7.3 5 2 1 7 7 7 4 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGR27769.1 - 0.3 11.2 19.6 3.2 8.0 0.1 7.1 7 0 0 7 7 7 0 Leucine Rich repeat LRR_1 PF00560.33 EGR27769.1 - 0.44 11.3 14.3 19 6.3 0.1 6.9 5 1 0 5 5 5 0 Leucine Rich Repeat Sld5 PF05916.11 EGR27770.1 - 0.00054 20.4 0.1 0.00088 19.7 0.1 1.4 1 0 0 1 1 1 1 GINS complex protein MORN PF02493.20 EGR27771.1 - 1.6e-52 172.3 77.7 9e-08 31.6 1.0 10.0 10 0 0 10 10 10 9 MORN repeat DUF448 PF04296.13 EGR27771.1 - 4.8 7.1 6.1 12 5.8 0.0 3.3 4 1 0 4 4 4 0 Protein of unknown function (DUF448) cNMP_binding PF00027.29 EGR27772.1 - 2.9e-13 49.7 0.0 4.1e-13 49.2 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF4699 PF15770.5 EGR27772.1 - 0.13 12.0 0.4 0.22 11.3 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) ZT_dimer PF16916.5 EGR27772.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Dimerisation domain of Zinc Transporter MORN PF02493.20 EGR27773.1 - 8.9e-30 100.8 47.2 2.4e-05 24.0 1.6 8.9 9 0 0 9 9 9 7 MORN repeat Ion_trans_2 PF07885.16 EGR27773.1 - 4e-07 29.9 2.7 4e-07 29.9 2.7 1.8 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 EGR27773.1 - 4.3e-06 26.1 1.9 7.1e-06 25.4 1.9 1.4 1 0 0 1 1 1 1 Ion transport protein Tudor_2 PF18104.1 EGR27773.1 - 0.046 13.4 3.3 10 5.9 0.1 4.0 4 0 0 4 4 4 0 Jumonji domain-containing protein 2A Tudor domain PPP5 PF08321.12 EGR27773.1 - 0.061 13.6 0.0 1.3 9.4 0.0 2.6 2 0 0 2 2 2 0 PPP5 TPR repeat region Hydrolase_4 PF12146.8 EGR27774.1 - 1.4e-07 31.1 0.0 0.00019 20.8 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR27774.1 - 1.6e-07 31.2 1.8 0.00014 21.6 0.1 2.9 2 1 1 3 3 3 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EGR27774.1 - 0.00031 20.4 0.0 0.0087 15.7 0.0 2.5 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 EGR27774.1 - 0.0095 15.6 0.0 0.032 13.9 0.0 2.0 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Lipase_3 PF01764.25 EGR27774.1 - 0.085 12.7 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Response_reg PF00072.24 EGR27776.1 - 1.2e-21 77.0 2.5 1.3e-21 76.8 0.1 2.5 4 0 0 4 4 4 1 Response regulator receiver domain HATPase_c PF02518.26 EGR27776.1 - 4.3e-16 59.4 0.3 9e-16 58.4 0.3 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGR27776.1 - 5.1e-05 23.2 0.6 0.00016 21.7 0.1 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EGR27776.1 - 0.0014 18.5 0.5 0.0036 17.1 0.4 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF2431 PF10354.9 EGR27776.1 - 0.043 14.1 0.2 0.11 12.8 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF2431) RNase_HII PF01351.18 EGR27776.1 - 0.16 11.8 1.9 1.2 8.9 1.6 2.4 2 0 0 2 2 2 0 Ribonuclease HII tRNA_synthFbeta PF17759.1 EGR27777.1 - 6.4e-41 140.1 0.0 9.7e-41 139.5 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain B3_4 PF03483.17 EGR27777.1 - 1.7e-23 83.2 0.1 4.2e-23 81.9 0.1 1.7 1 0 0 1 1 1 1 B3/4 domain PhetRS_B1 PF18262.1 EGR27777.1 - 1.6e-19 69.9 1.0 4.4e-18 65.3 0.2 2.7 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B5 PF03484.15 EGR27777.1 - 5.3e-12 45.9 0.0 3.9e-10 39.9 0.0 2.6 2 0 0 2 2 2 1 tRNA synthetase B5 domain FlaC_arch PF05377.11 EGR27778.1 - 8.4 6.9 22.4 0.38 11.2 1.4 5.4 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) Pkinase PF00069.25 EGR27779.1 - 9.7e-62 208.7 4.4 1.3e-61 208.3 4.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27779.1 - 1.2e-38 132.9 0.3 1.5e-38 132.6 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27779.1 - 3.5e-05 23.3 0.0 5.2e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGR27779.1 - 0.00011 21.3 2.2 0.00011 21.3 2.2 2.2 1 1 0 2 2 2 1 Haspin like kinase domain DUF5121 PF17165.4 EGR27780.1 - 0.014 15.8 1.1 0.014 15.8 1.1 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF5121) Evr1_Alr PF04777.13 EGR27781.1 - 0.35 11.4 0.1 0.35 11.4 0.1 3.0 3 1 0 3 3 3 0 Erv1 / Alr family TLD PF07534.16 EGR27782.1 - 7.2e-37 126.7 3.5 7.2e-37 126.7 3.5 3.1 2 1 1 3 3 3 1 TLD LysM PF01476.20 EGR27782.1 - 0.00025 21.0 0.0 0.001 19.1 0.0 2.1 1 0 0 1 1 1 1 LysM domain SKICH PF17751.1 EGR27782.1 - 0.012 16.2 5.2 2.2 8.8 0.3 3.1 2 0 0 2 2 2 0 SKICH domain DnaJ_C PF01556.18 EGR27783.1 - 2.1e-32 112.3 0.6 3.1e-32 111.7 0.6 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGR27783.1 - 6.2e-16 58.3 0.8 1.8e-15 56.8 0.8 1.9 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGR27783.1 - 4.4e-10 39.8 17.3 9.4e-10 38.7 17.3 1.6 1 0 0 1 1 1 1 DnaJ central domain DZR PF12773.7 EGR27783.1 - 4.2 7.5 9.7 12 6.0 9.7 1.8 1 1 0 1 1 1 0 Double zinc ribbon Anti-TRAP PF15777.5 EGR27783.1 - 5.8 7.0 12.5 12 5.9 2.7 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Peptidase_M8 PF01457.16 EGR27784.1 - 2.4e-39 135.4 12.7 5.7e-34 117.7 0.3 2.2 1 1 1 2 2 2 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR27784.1 - 0.025 14.6 7.7 0.074 13.1 7.7 1.9 1 0 0 1 1 1 0 Tenascin EGF domain RIH_assoc PF08454.11 EGR27785.1 - 3.4e-31 107.1 7.9 3.4e-31 107.1 7.9 3.7 3 0 0 3 3 3 2 RyR and IP3R Homology associated BK_channel_a PF03493.18 EGR27786.1 - 1.3e-32 111.9 0.8 8.7e-28 96.4 0.0 2.8 2 0 0 2 2 2 2 Calcium-activated BK potassium channel alpha subunit TrkA_N PF02254.18 EGR27786.1 - 8.5e-05 22.8 0.0 0.73 10.1 0.0 2.9 2 0 0 2 2 2 2 TrkA-N domain Ion_trans_2 PF07885.16 EGR27786.1 - 0.0037 17.2 0.7 0.038 13.9 0.2 2.4 2 0 0 2 2 2 1 Ion channel DUF2975 PF11188.8 EGR27786.1 - 0.058 13.3 0.2 0.16 11.9 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) PhoLip_ATPase_C PF16212.5 EGR27787.1 - 2.9e-65 220.5 24.7 2.9e-65 220.5 24.7 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EGR27787.1 - 6.6e-13 49.4 0.0 8.6e-06 26.2 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGR27787.1 - 6.5e-10 39.0 2.0 6.2e-09 35.8 0.0 3.0 3 0 0 3 3 3 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGR27787.1 - 3.4e-07 30.0 0.0 1e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.7 EGR27787.1 - 0.02 15.3 0.0 0.47 10.8 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 EGR27789.1 - 5e-15 55.6 0.2 8e-14 51.6 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27789.1 - 1.3e-07 31.2 0.0 1.7e-05 24.2 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGR27789.1 - 0.019 14.3 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like DUF2552 PF10827.8 EGR27789.1 - 0.038 14.2 1.6 6.6 7.0 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2552) NPV_P10 PF05531.12 EGR27789.1 - 0.53 10.8 5.3 0.38 11.2 2.6 2.1 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Adaptin_N PF01602.20 EGR27790.1 - 1.5e-115 386.7 16.0 2.1e-115 386.3 16.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EGR27790.1 - 9.4e-13 48.5 5.4 9.4e-13 48.5 5.4 2.6 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 EGR27790.1 - 1.1e-05 25.6 10.9 0.00027 21.0 0.4 3.4 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 DUF4366 PF14283.6 EGR27790.1 - 0.018 15.1 1.2 0.048 13.7 1.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) TFIIA PF03153.13 EGR27790.1 - 1 9.3 21.3 1.7 8.6 21.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ion_trans PF00520.31 EGR27791.1 - 3.9e-20 72.1 18.6 5e-20 71.8 18.6 1.0 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGR27791.1 - 9.3e-09 35.1 0.3 9.3e-09 35.1 0.3 2.7 3 0 0 3 3 3 1 Ion channel DUF2339 PF10101.9 EGR27791.1 - 0.049 12.2 0.1 0.057 12.0 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2339) TPR_12 PF13424.6 EGR27795.1 - 0.00055 20.2 0.8 1.7 9.0 0.0 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGR27795.1 - 0.00056 19.6 2.4 2 8.3 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGR27795.1 - 0.0046 17.0 7.0 13 6.2 0.2 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGR27795.1 - 0.12 12.9 2.1 12 6.5 0.8 3.9 4 2 1 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGR27795.1 - 0.49 10.7 9.6 11 6.6 0.3 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Cpn60_TCP1 PF00118.24 EGR27796.1 - 1.7e-154 515.1 5.1 2e-154 514.9 5.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family pRN1_helical PF13010.6 EGR27797.1 - 0.029 14.3 0.2 0.035 14.1 0.2 1.3 1 0 0 1 1 1 0 Primase helical domain DUF4925 PF16272.5 EGR27797.1 - 0.038 13.5 0.1 0.042 13.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4925) Corona_NSP4_C PF16348.5 EGR27797.1 - 0.088 13.6 0.3 0.098 13.5 0.3 1.1 1 0 0 1 1 1 0 Coronavirus nonstructural protein 4 C-terminus Kinesin PF00225.23 EGR27798.1 - 8.4e-57 192.6 9.9 8.4e-57 192.6 9.9 2.7 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGR27798.1 - 2.2e-14 53.7 1.1 2.2e-14 53.7 1.1 5.2 4 3 2 6 6 6 1 Microtubule binding EF1G PF00647.19 EGR27799.1 - 7.7e-28 96.7 3.1 8.9e-28 96.5 0.4 2.4 3 0 0 3 3 3 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 EGR27799.1 - 5.2e-15 55.5 0.0 1.5e-14 54.1 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGR27799.1 - 6.9e-12 45.4 0.1 6.9e-12 45.4 0.1 2.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGR27799.1 - 5.7e-09 36.3 0.0 1.7e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGR27799.1 - 1.3e-06 28.5 0.2 1.3e-06 28.5 0.2 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGR27799.1 - 1.8e-06 28.2 0.0 5.5e-06 26.6 0.0 1.9 2 0 0 2 2 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGR27799.1 - 2.4e-06 27.5 0.0 7.6e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain DUF3391 PF11871.8 EGR27799.1 - 0.018 15.6 3.3 0.041 14.4 3.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) RP-C_C PF11800.8 EGR27799.1 - 0.022 14.9 2.7 0.034 14.2 2.7 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF1764 PF08576.10 EGR27799.1 - 0.032 15.1 7.1 0.082 13.8 7.1 1.7 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) GST_N_5 PF18485.1 EGR27799.1 - 0.033 14.5 0.0 0.22 11.9 0.0 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain Neur_chan_memb PF02932.16 EGR27799.1 - 0.12 12.4 1.4 0.22 11.5 1.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 EGR27799.1 - 0.24 10.6 1.8 0.33 10.1 1.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter AP-5_subunit_s1 PF15001.6 EGR27799.1 - 0.57 10.2 5.5 1.1 9.2 5.5 1.4 1 0 0 1 1 1 0 AP-5 complex subunit sigma-1 Androgen_recep PF02166.16 EGR27799.1 - 0.95 8.2 12.9 1.4 7.7 12.9 1.1 1 0 0 1 1 1 0 Androgen receptor Presenilin PF01080.17 EGR27799.1 - 4.8 5.8 7.7 7.1 5.3 7.7 1.1 1 0 0 1 1 1 0 Presenilin NDK PF00334.19 EGR27800.1 - 1.2e-70 235.8 0.0 6.8e-41 139.4 0.0 2.3 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 EGR27800.1 - 0.00042 20.1 1.7 0.009 15.8 1.3 2.9 2 1 0 2 2 2 1 DUF1126 PH-like domain PX PF00787.24 EGR27801.1 - 1.3e-22 79.9 12.4 2.7e-11 43.4 3.3 2.3 2 0 0 2 2 2 2 PX domain MobA_MobL PF03389.15 EGR27801.1 - 0.033 13.9 0.2 0.074 12.8 0.1 1.7 2 1 0 2 2 2 0 MobA/MobL family Kinase-PPPase PF03618.14 EGR27801.1 - 0.036 13.8 0.7 2.2 8.0 0.1 2.3 2 0 0 2 2 2 0 Kinase/pyrophosphorylase CHIP_TPR_N PF18391.1 EGR27801.1 - 0.048 14.4 8.5 0.31 11.8 0.4 2.9 2 1 0 2 2 2 0 CHIP N-terminal tetratricopeptide repeat domain DICT PF10069.9 EGR27801.1 - 0.38 10.5 4.9 0.31 10.8 1.4 2.1 2 0 0 2 2 2 0 Sensory domain in DIguanylate Cyclases and Two-component system Ras PF00071.22 EGR27802.1 - 2.5e-59 199.5 3.7 4.1e-59 198.8 3.7 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR27802.1 - 8.8e-35 119.5 0.4 8.8e-35 119.5 0.4 2.2 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR27802.1 - 1.3e-17 63.8 0.8 2.3e-17 63.0 0.8 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR27802.1 - 1.1e-09 38.3 0.1 1.1e-09 38.3 0.1 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGR27802.1 - 0.00014 21.4 3.0 0.00055 19.5 1.7 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGR27802.1 - 0.00067 19.1 2.3 0.00075 19.0 1.4 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EGR27802.1 - 0.00093 18.8 0.6 0.0073 15.9 0.6 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGR27802.1 - 0.0013 18.6 7.9 0.032 14.1 0.6 3.1 1 1 2 3 3 3 2 RsgA GTPase TniB PF05621.11 EGR27802.1 - 0.031 13.7 0.4 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein GEMIN8 PF15348.6 EGR27803.1 - 0.21 11.8 14.0 0.23 11.7 14.0 1.0 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 CAF-1_p150 PF11600.8 EGR27803.1 - 0.33 10.7 36.9 0.37 10.5 36.9 1.0 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Phage_Gp23 PF10669.9 EGR27803.1 - 5.8 7.3 21.5 7.6 6.9 21.5 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Ccdc124 PF06244.12 EGR27804.1 - 2e-26 93.1 0.8 2.1e-26 93.0 0.8 1.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 ABC_tran PF00005.27 EGR27805.1 - 3.1e-19 69.9 0.1 3.1e-19 69.9 0.1 2.0 2 1 1 3 3 3 1 ABC transporter AAA_23 PF13476.6 EGR27805.1 - 9.3e-05 23.0 13.9 9.3e-05 23.0 13.9 3.1 2 1 1 3 3 3 1 AAA domain ABC2_membrane_3 PF12698.7 EGR27805.1 - 0.0049 16.0 24.2 0.0049 16.0 24.2 2.7 2 2 0 2 2 2 1 ABC-2 family transporter protein SRP54 PF00448.22 EGR27805.1 - 0.006 16.2 0.3 0.006 16.2 0.3 1.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain DUF4710 PF15828.5 EGR27805.1 - 0.0088 16.1 0.1 0.033 14.3 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4710) AAA_30 PF13604.6 EGR27805.1 - 0.02 14.6 0.0 0.039 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGR27805.1 - 0.029 14.3 0.2 0.029 14.3 0.2 2.5 4 0 0 4 4 4 0 RsgA GTPase AAA_27 PF13514.6 EGR27805.1 - 0.029 14.0 0.0 0.029 14.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 EGR27805.1 - 0.032 14.0 0.2 0.07 12.9 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EGR27806.1 - 7.3e-26 91.3 0.0 1.9e-25 90.0 0.0 1.7 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGR27806.1 - 1.5e-09 37.5 36.8 1.5e-09 37.5 36.8 2.5 2 2 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGR27806.1 - 7.9e-07 29.2 0.0 0.041 13.7 0.2 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGR27806.1 - 0.035 13.8 0.1 0.1 12.3 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF5442 PF17514.2 EGR27806.1 - 0.64 10.2 8.2 0.15 12.3 1.2 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5442) PP2C PF00481.21 EGR27807.1 - 1.2e-71 241.3 0.1 1.5e-71 241.0 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C DUF846 PF05832.12 EGR27808.1 - 1.1e-35 122.7 19.8 1.3e-35 122.5 19.8 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) UIM PF02809.20 EGR27809.1 - 0.0028 17.5 0.6 0.0028 17.5 0.6 3.2 3 1 0 3 3 3 1 Ubiquitin interaction motif FAM176 PF14851.6 EGR27809.1 - 0.0052 16.5 3.8 0.0071 16.0 3.8 1.1 1 0 0 1 1 1 1 FAM176 family PH_4 PF15404.6 EGR27809.1 - 0.039 13.7 1.0 0.044 13.6 1.0 1.0 1 0 0 1 1 1 0 Pleckstrin homology domain NOA36 PF06524.12 EGR27809.1 - 3.2 7.0 8.2 3.4 6.9 8.2 1.0 1 0 0 1 1 1 0 NOA36 protein Importin_rep_4 PF18808.1 EGR27811.1 - 2.3e-07 31.0 0.9 1.2e-05 25.4 0.1 3.1 2 1 1 3 3 3 1 Importin repeat HEAT PF02985.22 EGR27811.1 - 0.00054 20.0 0.3 7.4 7.1 0.0 4.6 4 0 0 4 4 4 1 HEAT repeat RIX1 PF08167.12 EGR27811.1 - 0.0068 16.2 1.6 0.0068 16.2 1.6 2.3 1 1 0 2 2 2 1 rRNA processing/ribosome biogenesis EF-hand_2 PF09068.11 EGR27811.1 - 0.029 14.5 1.2 0.063 13.4 0.0 2.1 2 1 0 2 2 2 0 EF hand Telomere_reg-2 PF10193.9 EGR27811.1 - 0.038 14.4 0.6 0.038 14.4 0.6 3.7 3 1 0 3 3 3 0 Telomere length regulation protein DUF1981 PF09324.10 EGR27811.1 - 1 9.2 8.0 0.5 10.3 0.6 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) DUF3837 PF12939.7 EGR27811.1 - 1.9 9.0 5.2 6.9 7.1 0.2 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF3837) MGDG_synth PF06925.11 EGR27811.1 - 1.9 8.5 8.3 1.8 8.6 1.4 3.0 3 0 0 3 3 3 0 Monogalactosyldiacylglycerol (MGDG) synthase RAC_head PF16717.5 EGR27811.1 - 3.7 8.6 7.6 8.8 7.4 0.0 3.7 4 0 0 4 4 4 0 Ribosome-associated complex head domain POT1 PF02765.17 EGR27812.1 - 0.0032 17.3 0.1 0.01 15.7 0.1 1.9 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 Mob_Pre PF01076.19 EGR27812.1 - 0.045 13.6 0.6 2.2 8.1 0.0 2.5 2 0 0 2 2 2 0 Plasmid recombination enzyme PNPase PF03726.14 EGR27812.1 - 0.1 13.1 5.4 0.22 12.0 1.3 2.8 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Peptidase_S41_N PF11918.8 EGR27812.1 - 0.11 12.7 2.8 0.41 10.9 2.3 2.2 2 0 0 2 2 2 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP Ipi1_N PF12333.8 EGR27812.1 - 0.24 12.0 5.3 13 6.5 0.4 4.4 4 1 1 5 5 5 0 Rix1 complex component involved in 60S ribosome maturation PRD PF00874.20 EGR27812.1 - 2.6 8.4 13.0 1.4 9.2 2.3 3.7 2 1 1 3 3 3 0 PRD domain Pkinase PF00069.25 EGR27813.1 - 1.9e-76 256.9 0.1 2.2e-76 256.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27813.1 - 4.7e-36 124.4 0.0 6.1e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27813.1 - 3.9e-05 23.1 0.1 6.3e-05 22.4 0.1 1.4 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGR27813.1 - 0.0017 17.4 1.7 0.0023 16.9 1.7 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EGR27813.1 - 0.0035 17.0 1.1 0.25 10.9 0.3 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGR27813.1 - 0.0038 16.1 0.0 0.0063 15.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_C PF00433.24 EGR27813.1 - 0.12 13.1 0.5 0.39 11.5 0.5 1.9 1 0 0 1 1 1 0 Protein kinase C terminal domain MFS_1 PF07690.16 EGR27814.1 - 9.1e-25 87.3 33.5 3.7e-09 36.0 12.5 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily WBP-1 PF11669.8 EGR27814.1 - 6.5 7.4 6.9 30 5.3 3.5 2.7 2 0 0 2 2 2 0 WW domain-binding protein 1 Lipase_3 PF01764.25 EGR27815.1 - 9.5e-28 96.8 0.0 2.4e-27 95.5 0.0 1.6 2 0 0 2 2 2 1 Lipase (class 3) MFS_1 PF07690.16 EGR27815.1 - 2.4e-18 66.2 14.4 1.5e-10 40.6 12.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Hydrolase_4 PF12146.8 EGR27815.1 - 0.0052 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 EGR27815.1 - 0.01 15.4 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF2974 PF11187.8 EGR27815.1 - 0.042 13.4 0.0 0.11 12.1 0.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2974) DHHC PF01529.20 EGR27816.1 - 7.9e-30 103.7 22.1 7.9e-30 103.7 22.1 2.4 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.6 EGR27816.1 - 2.3e-08 34.1 0.1 4.8e-08 33.1 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGR27816.1 - 5.4e-06 26.6 0.3 1.3e-05 25.4 0.3 1.6 1 0 0 1 1 1 1 Ankyrin repeat Ank_2 PF12796.7 EGR27816.1 - 6.6e-05 23.4 0.0 0.00016 22.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGR27816.1 - 0.00016 21.8 0.1 0.0011 19.3 0.1 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EGR27816.1 - 0.03 14.9 0.0 0.075 13.6 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF572 PF04502.13 EGR27818.1 - 1.6e-29 103.6 8.4 1.6e-29 103.6 8.4 2.5 2 2 0 2 2 2 1 Family of unknown function (DUF572) Nudc_N PF14050.6 EGR27818.1 - 5e-19 68.0 2.1 8.9e-19 67.2 0.6 2.3 2 0 0 2 2 2 1 N-terminal conserved domain of Nudc. Cyt-b5 PF00173.28 EGR27818.1 - 6.6e-17 61.4 0.1 1.4e-16 60.4 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CS PF04969.16 EGR27818.1 - 1.4e-10 42.0 6.3 1e-09 39.3 6.3 2.6 1 1 0 1 1 1 1 CS domain 7TM_GPCR_Srd PF10317.9 EGR27818.1 - 0.048 12.8 0.5 0.089 12.0 0.5 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd GAGA_bind PF06217.12 EGR27818.1 - 0.099 12.9 13.4 0.31 11.3 3.1 2.3 2 0 0 2 2 2 0 GAGA binding protein-like family Lipocalin_2 PF08212.12 EGR27819.1 - 7.4e-17 61.6 0.0 9.5e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 EGR27819.1 - 0.0016 18.6 0.1 0.0021 18.3 0.1 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family cNMP_binding PF00027.29 EGR27820.1 - 2.5e-27 94.7 0.1 3.5e-16 59.0 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Lactamase_B_2 PF12706.7 EGR27820.1 - 0.00057 19.4 0.0 0.0021 17.6 0.0 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGR27820.1 - 0.0018 18.3 0.0 0.0038 17.3 0.0 1.5 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF812 PF05667.11 EGR27821.1 - 0.12 11.2 21.6 0.14 11.0 21.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FAM76 PF16046.5 EGR27821.1 - 0.69 9.2 20.8 0.8 9.0 20.8 1.0 1 0 0 1 1 1 0 FAM76 protein Dapper PF15268.6 EGR27821.1 - 0.93 8.3 13.2 1 8.1 13.2 1.0 1 0 0 1 1 1 0 Dapper Zip PF02535.22 EGR27821.1 - 1.1 8.4 5.0 1.1 8.4 5.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NESP55 PF06390.12 EGR27821.1 - 1.5 8.3 7.8 6.5 6.3 7.9 1.7 1 1 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Macoilin PF09726.9 EGR27821.1 - 3.6 6.0 21.6 4.8 5.6 21.6 1.1 1 0 0 1 1 1 0 Macoilin family Secretin PF00263.21 EGR27821.1 - 8.7 6.0 21.8 17 5.0 21.7 1.6 1 1 0 1 1 1 0 Bacterial type II and III secretion system protein TPH PF13868.6 EGR27822.1 - 1.1e-64 218.2 143.3 1.1e-64 218.2 143.3 2.1 2 0 0 2 2 2 1 Trichohyalin-plectin-homology domain Peptidase_S11 PF00768.20 EGR27823.1 - 9.3e-41 139.8 0.6 1.6e-19 70.4 0.0 2.1 2 0 0 2 2 2 2 D-alanyl-D-alanine carboxypeptidase DnaGprimase_HBD PF16730.5 EGR27823.1 - 0.033 14.3 0.1 0.033 14.3 0.1 2.8 4 0 0 4 4 4 0 DnaG-primase C-terminal, helicase-binding domain PTP_tm PF18861.1 EGR27823.1 - 0.27 11.2 3.6 0.09 12.8 0.4 1.7 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J AMPK1_CBM PF16561.5 EGR27824.1 - 6.3e-30 103.2 2.9 6.3e-30 103.2 2.9 2.8 3 0 0 3 3 3 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EGR27824.1 - 5.5e-07 29.8 6.7 3.7e-06 27.1 6.7 2.3 1 1 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain Cue1_U7BR PF18499.1 EGR27824.1 - 0.064 13.3 3.1 5 7.3 0.4 3.2 3 0 0 3 3 3 0 Ubc7p-binding region of Cue1 PRP3 PF08572.10 EGR27825.1 - 1.5e-50 172.0 16.8 2.4e-50 171.4 16.8 1.3 1 0 0 1 1 1 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EGR27825.1 - 1.5e-38 132.2 0.1 1.5e-38 132.2 0.1 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF1115) Porin_5 PF16930.5 EGR27825.1 - 0.22 9.9 2.9 0.63 8.5 0.1 2.2 2 0 0 2 2 2 0 Putative porin Rrp44_CSD1 PF17216.3 EGR27827.1 - 0.0026 17.5 0.1 0.0051 16.5 0.1 1.5 1 0 0 1 1 1 1 Rrp44-like cold shock domain PP2C PF00481.21 EGR27828.1 - 1.8e-17 63.8 0.0 1.8e-17 63.8 0.0 3.1 2 2 2 4 4 4 1 Protein phosphatase 2C Pkinase PF00069.25 EGR27829.1 - 1.1e-75 254.4 1.2 1.1e-75 254.4 1.2 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27829.1 - 2.1e-47 161.6 0.1 4.3e-47 160.6 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27829.1 - 1.2e-07 31.3 0.5 2.8e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR27829.1 - 0.0014 17.5 0.1 0.0014 17.5 0.1 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGR27829.1 - 0.0062 15.9 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR27829.1 - 0.026 14.4 0.0 0.041 13.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ras PF00071.22 EGR27830.1 - 6.4e-51 172.2 2.7 7.3e-51 172.0 2.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR27830.1 - 2.9e-33 114.6 0.3 2.9e-33 114.6 0.3 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR27830.1 - 1.4e-12 47.4 0.7 1.6e-12 47.2 0.7 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGR27830.1 - 3.7e-05 23.2 0.4 4.6e-05 22.9 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGR27830.1 - 7.7e-05 22.2 0.3 9.2e-05 21.9 0.3 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EGR27830.1 - 0.0017 17.9 0.7 0.0055 16.3 0.7 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGR27830.1 - 0.0024 17.9 0.1 0.0064 16.6 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EGR27830.1 - 0.013 15.2 0.4 2.3 8.0 0.1 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EGR27830.1 - 0.015 15.3 1.1 0.46 10.4 0.1 2.5 1 1 2 3 3 3 0 RsgA GTPase TniB PF05621.11 EGR27830.1 - 0.018 14.4 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 EGR27830.1 - 0.02 14.6 0.2 0.1 12.3 0.2 2.0 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGR27830.1 - 0.023 14.7 1.0 0.2 11.7 0.4 2.5 1 1 1 2 2 2 0 AAA domain CsgF PF10614.9 EGR27830.1 - 0.26 11.5 0.1 0.26 11.5 0.1 2.0 2 0 0 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein Alpha-amylase PF00128.24 EGR27831.1 - 1.5e-55 189.1 3.1 7.7e-55 186.8 3.1 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain GHL6 PF14871.6 EGR27831.1 - 0.07 13.3 0.0 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 GCP_C_terminal PF04130.13 EGR27832.1 - 0.046 13.2 1.5 0.078 12.4 0.9 1.6 2 0 0 2 2 2 0 Gamma tubulin complex component C-terminal Serglycin PF04360.12 EGR27832.1 - 0.13 12.2 0.1 1.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Serglycin GILT PF03227.16 EGR27833.1 - 1.5e-13 50.9 1.7 1.5e-13 50.9 1.7 2.0 2 1 0 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Ndc1_Nup PF09531.10 EGR27834.1 - 0.00028 19.8 28.5 0.00038 19.3 28.5 1.4 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Caldesmon PF02029.15 EGR27834.1 - 0.0013 17.5 27.3 0.0014 17.5 27.3 1.1 1 0 0 1 1 1 1 Caldesmon Dapper PF15268.6 EGR27834.1 - 0.002 17.1 43.6 0.0021 17.0 43.6 1.1 1 0 0 1 1 1 1 Dapper Macoilin PF09726.9 EGR27834.1 - 0.0024 16.5 24.1 0.003 16.2 24.1 1.3 1 0 0 1 1 1 1 Macoilin family DUF966 PF06136.13 EGR27834.1 - 0.26 11.0 34.4 0.35 10.6 34.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) DUF3877 PF12993.7 EGR27835.1 - 0.034 14.0 2.1 0.11 12.4 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function, E. rectale Gene description (DUF3877) HD_2 PF12917.7 EGR27835.1 - 0.059 13.1 1.1 0.53 10.0 0.2 2.3 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme NDUF_B6 PF09782.9 EGR27836.1 - 4 7.5 6.1 1.2 9.2 3.1 1.6 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit PP2C PF00481.21 EGR27837.1 - 3.5e-64 216.9 0.0 3.5e-64 216.9 0.0 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C YEATS PF03366.16 EGR27837.1 - 1.3e-27 95.6 1.6 2.9e-27 94.4 1.6 1.7 1 0 0 1 1 1 1 YEATS family Coq4 PF05019.13 EGR27838.1 - 2.4e-64 216.7 1.2 2.5e-64 216.6 0.1 1.6 2 0 0 2 2 2 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 CDPS PF16715.5 EGR27838.1 - 0.17 11.5 4.2 0.21 11.2 3.3 1.4 1 1 0 1 1 1 0 Cyclodipeptide synthase CENP-F_leu_zip PF10473.9 EGR27838.1 - 3 7.9 30.6 2.1 8.4 12.5 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 EGR27838.1 - 4.1 8.1 27.7 13 6.5 11.4 3.2 1 1 1 2 2 2 0 Initiation control protein YabA Clathrin PF00637.20 EGR27839.1 - 7.6e-172 564.0 67.6 6.1e-29 100.7 3.9 8.3 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 EGR27839.1 - 3.3e-23 81.4 0.5 2.8e-22 78.4 0.4 2.8 2 0 0 2 2 2 1 Clathrin-H-link Coatomer_WDAD PF04053.14 EGR27839.1 - 3.3e-09 36.3 8.9 0.0026 16.9 0.0 5.2 5 0 0 5 5 5 3 Coatomer WD associated region TPR_8 PF13181.6 EGR27839.1 - 1.8e-05 24.6 0.0 0.26 11.6 0.0 4.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGR27839.1 - 2.9e-05 23.7 0.2 0.35 10.8 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGR27839.1 - 0.00073 19.5 0.4 4.5 7.6 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGR27839.1 - 0.011 16.2 4.9 2.3 8.8 0.0 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGR27839.1 - 0.71 10.6 2.3 60 4.6 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat MPC PF03650.13 EGR27840.1 - 1e-26 93.2 0.4 1.4e-26 92.8 0.4 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers PAP_central PF04928.17 EGR27841.1 - 1e-35 123.0 1.0 1.4e-35 122.5 1.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain Nrap_D2 PF17403.2 EGR27841.1 - 0.00064 19.5 0.2 0.00064 19.5 0.2 1.6 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Linker_histone PF00538.19 EGR27841.1 - 0.13 12.6 2.2 0.15 12.4 0.1 2.1 2 0 0 2 2 2 0 linker histone H1 and H5 family H_PPase PF03030.16 EGR27842.1 - 4.8e-13 48.6 15.4 1e-10 40.9 15.4 2.1 1 1 0 1 1 1 1 Inorganic H+ pyrophosphatase CRAL_TRIO PF00650.20 EGR27843.1 - 5.2e-19 68.5 0.1 7.1e-19 68.1 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain SAS-6_N PF16531.5 EGR27844.1 - 1.3e-21 76.9 8.2 1.3e-21 76.9 8.2 4.3 3 2 0 3 3 3 1 Centriolar protein SAS N-terminal Pkinase PF00069.25 EGR27845.1 - 1.8e-38 132.5 0.0 2.9e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27845.1 - 3.2e-13 49.6 0.0 5.5e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1910 PF08928.10 EGR27845.1 - 0.016 15.2 1.2 0.41 10.7 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) Pkinase_fungal PF17667.1 EGR27845.1 - 0.029 13.2 1.2 0.029 13.2 0.1 1.5 2 0 0 2 2 2 0 Fungal protein kinase Swi5 PF07061.11 EGR27845.1 - 0.059 13.5 1.0 0.059 13.5 1.0 2.1 3 0 0 3 3 3 0 Swi5 Kdo PF06293.14 EGR27845.1 - 0.11 11.8 0.0 0.17 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EGR27846.1 - 8.5e-06 25.3 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27846.1 - 0.049 12.9 0.0 0.066 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase PH_3 PF14593.6 EGR27846.1 - 0.063 13.4 0.0 0.15 12.2 0.0 1.8 1 1 0 1 1 1 0 PH domain Pkinase PF00069.25 EGR27847.1 - 1.1e-71 241.3 0.8 1.4e-71 241.0 0.8 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27847.1 - 5.3e-33 114.4 0.1 7.6e-33 113.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27847.1 - 4.3e-08 32.8 0.3 9.4e-08 31.7 0.3 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR27847.1 - 0.00099 18.0 0.0 0.0013 17.6 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EGR27847.1 - 0.002 17.3 0.0 0.0032 16.6 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 PIP49_C PF12260.8 EGR27847.1 - 0.0025 17.5 1.4 0.0026 17.4 0.1 1.6 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 FTA2 PF13095.6 EGR27847.1 - 0.04 13.5 3.1 0.65 9.6 0.1 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGR27847.1 - 0.17 11.8 0.0 0.89 9.4 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ras PF00071.22 EGR27848.1 - 0.046 13.3 0.0 0.065 12.8 0.0 1.2 1 0 0 1 1 1 0 Ras family Yip1 PF04893.17 EGR27849.1 - 0.00079 19.2 0.2 0.00079 19.2 0.2 2.8 1 1 1 2 2 2 1 Yip1 domain YIF1 PF03878.15 EGR27849.1 - 0.84 9.1 16.2 5.7 6.4 11.9 2.1 1 1 1 2 2 2 0 YIF1 NDUFA12 PF05071.16 EGR27850.1 - 6.6e-18 65.3 4.3 1e-17 64.7 4.3 1.3 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 ECH_1 PF00378.20 EGR27851.1 - 4.3e-58 196.6 0.0 5.5e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGR27851.1 - 5e-33 115.0 0.0 7.5e-31 107.9 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase APOBEC3 PF18771.1 EGR27851.1 - 0.061 13.4 0.1 0.15 12.2 0.1 1.7 1 0 0 1 1 1 0 APOBEC3 Actin PF00022.19 EGR27852.1 - 1.4e-92 310.4 0.1 4e-71 239.8 0.1 2.7 1 1 1 2 2 2 2 Actin Actin_micro PF17003.5 EGR27852.1 - 0.0025 17.1 0.1 0.0039 16.4 0.1 1.3 1 0 0 1 1 1 1 Putative actin-like family Ion_trans_2 PF07885.16 EGR27853.1 - 2.2e-13 50.0 0.1 3e-13 49.5 0.1 1.2 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGR27853.1 - 6.8e-08 32.0 0.7 1e-07 31.5 0.7 1.2 1 0 0 1 1 1 1 Ion transport protein DUF4796 PF16044.5 EGR27853.1 - 0.04 13.5 0.5 0.044 13.4 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4796) Zip PF02535.22 EGR27854.1 - 2.3e-49 168.5 7.2 2.6e-49 168.2 7.2 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Herpes_Helicase PF02689.14 EGR27854.1 - 0.055 11.4 0.9 0.073 11.0 0.9 1.1 1 0 0 1 1 1 0 Helicase TPX2_importin PF12214.8 EGR27854.1 - 0.58 10.3 3.2 0.85 9.8 3.2 1.2 1 0 0 1 1 1 0 Cell cycle regulated microtubule associated protein CheZ PF04344.13 EGR27855.1 - 0.021 14.7 0.1 0.024 14.5 0.1 1.1 1 0 0 1 1 1 0 Chemotaxis phosphatase, CheZ Memo PF01875.17 EGR27856.1 - 2.4e-54 184.3 0.0 2.9e-54 184.1 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Dynein_light PF01221.18 EGR27857.1 - 1.8e-27 95.5 1.2 1.8e-27 95.5 1.2 1.4 2 0 0 2 2 2 1 Dynein light chain type 1 Citrate_synt PF00285.21 EGR27858.1 - 3.3e-11 42.9 0.0 5e-11 42.3 0.0 1.3 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Ribosomal_L28e PF01778.17 EGR27858.1 - 9.4e-05 23.1 0.8 0.00011 22.9 0.8 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family Citrate_synt PF00285.21 EGR27860.1 - 6.2e-32 111.1 0.0 7.9e-32 110.7 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain STAT2_C PF12188.8 EGR27860.1 - 0.01 15.8 0.0 0.044 13.7 0.0 2.0 2 0 0 2 2 2 0 Signal transducer and activator of transcription 2 C terminal DUF3107 PF11305.8 EGR27860.1 - 0.079 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3107) LRR_9 PF14580.6 EGR27861.1 - 8.5e-57 191.4 7.1 8.5e-57 191.4 7.1 1.7 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 EGR27861.1 - 6.5e-10 39.1 33.2 4.1e-05 23.8 9.4 4.0 2 1 4 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGR27861.1 - 4e-07 29.7 15.6 0.00023 20.9 8.2 2.9 1 1 2 3 3 3 3 Leucine rich repeat WTX PF09422.10 EGR27861.1 - 0.053 12.6 0.3 0.11 11.6 0.0 1.6 2 0 0 2 2 2 0 WTX protein OSR1_C PF12202.8 EGR27861.1 - 1.4 9.2 6.0 0.77 10.0 2.8 2.2 2 0 0 2 2 2 0 Oxidative-stress-responsive kinase 1 C-terminal domain DNA_pol3_a_NI PF14480.6 EGR27862.1 - 0.026 14.5 2.0 0.16 12.0 0.3 2.4 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus I FAT PF02259.23 EGR27864.1 - 1.4e-06 27.8 3.7 1.4e-06 27.8 3.7 3.8 4 0 0 4 4 4 2 FAT domain DUF5360 PF17314.2 EGR27864.1 - 0.0047 17.0 0.2 0.013 15.6 0.2 1.7 1 0 0 1 1 1 1 Family of unknown function (DUF5360) FlgO PF17680.1 EGR27864.1 - 0.038 13.7 0.0 12 5.7 0.0 2.8 2 0 0 2 2 2 0 FlgO protein AAA_6 PF12774.7 EGR27865.1 - 5.4e-154 512.0 3.7 2.8e-153 509.7 0.0 3.1 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGR27865.1 - 1.6e-130 435.8 28.4 1.6e-130 435.8 28.4 3.9 3 1 1 4 4 3 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 EGR27865.1 - 9.8e-14 51.5 0.0 2.9e-06 27.3 0.0 4.2 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGR27865.1 - 0.00063 20.3 5.7 0.39 11.3 0.0 5.6 4 2 0 4 4 4 1 AAA domain AAA_22 PF13401.6 EGR27865.1 - 0.00096 19.4 1.1 2.8 8.2 0.0 4.4 4 0 0 4 4 4 1 AAA domain AAA PF00004.29 EGR27865.1 - 0.0016 18.9 4.8 0.12 12.8 0.0 4.9 5 1 0 5 5 5 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGR27865.1 - 0.0017 18.7 0.1 0.94 9.9 0.0 3.9 3 0 0 3 3 3 1 RNA helicase DUF853 PF05872.12 EGR27865.1 - 0.0026 16.4 0.2 1.5 7.3 0.0 2.4 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF853) AAA_16 PF13191.6 EGR27865.1 - 0.0033 17.8 0.0 0.41 11.0 0.0 3.2 2 0 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 EGR27865.1 - 0.027 14.2 0.1 1.4 8.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGR27865.1 - 0.087 12.3 9.0 2.2 7.8 0.1 4.4 4 0 0 4 4 4 0 P-loop containing dynein motor region AAA_33 PF13671.6 EGR27865.1 - 0.14 12.3 0.2 40 4.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_8 PF12780.7 EGR27866.1 - 2.4e-96 322.1 2.1 2.4e-96 322.1 2.1 2.6 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EGR27866.1 - 1.2e-86 290.7 7.1 1.1e-76 258.1 0.2 3.0 2 1 1 3 3 3 2 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EGR27866.1 - 1.8e-79 266.0 1.8 1.8e-79 266.0 1.8 3.8 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 EGR27866.1 - 1.5e-54 184.2 0.5 5.1e-54 182.5 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGR27866.1 - 1.1e-52 177.1 2.7 1.9e-46 157.0 0.2 3.4 3 0 0 3 3 3 2 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EGR27866.1 - 1.2e-26 93.5 19.2 3.2e-26 92.2 19.2 1.7 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 EGR27866.1 - 8e-14 51.7 5.1 6.2e-13 48.8 0.1 3.2 3 0 0 3 3 3 1 AAA+ lid domain AAA_7 PF12775.7 EGR27866.1 - 0.00038 20.0 0.2 0.0015 18.1 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region ERM PF00769.19 EGR27866.1 - 1.3 8.8 45.3 0.089 12.6 10.3 2.8 3 0 0 3 3 3 0 Ezrin/radixin/moesin family PLDc PF00614.22 EGR27867.1 - 6.4e-16 57.8 2.0 3.3e-08 33.4 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EGR27867.1 - 3.2e-15 56.2 1.3 3e-10 40.1 0.2 3.1 2 0 0 2 2 2 2 PLD-like domain SUA5 PF03481.13 EGR27867.1 - 0.066 13.8 0.1 0.22 12.1 0.1 1.9 1 0 0 1 1 1 0 Putative GTP-binding controlling metal-binding DUF4576 PF15144.6 EGR27868.1 - 0.1 12.5 0.2 0.1 12.5 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4576) DUF2284 PF10050.9 EGR27868.1 - 4.4 7.0 9.5 0.38 10.5 1.4 2.6 2 1 0 2 2 2 0 Predicted metal-binding protein (DUF2284) DUF1133 PF06576.11 EGR27868.1 - 7.5 5.9 7.3 5.9 6.3 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1133) Methyltransf_16 PF10294.9 EGR27869.1 - 7.3e-09 35.6 0.1 8.6e-09 35.4 0.1 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EGR27869.1 - 0.04 13.7 0.0 0.055 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain APOBEC1 PF18769.1 EGR27869.1 - 0.066 13.5 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 APOBEC1 PX PF00787.24 EGR27870.1 - 4e-11 42.9 1.2 4e-11 42.9 1.2 3.5 3 0 0 3 3 3 1 PX domain E2F_CC-MB PF16421.5 EGR27870.1 - 0.96 9.9 11.8 1.7 9.0 4.0 3.7 2 1 0 2 2 2 0 E2F transcription factor CC-MB domain AAA_18 PF13238.6 EGR27871.1 - 7.1e-06 26.6 0.0 7.1e-06 26.6 0.0 3.1 1 1 2 3 3 2 1 AAA domain Zeta_toxin PF06414.12 EGR27871.1 - 7.5e-05 22.1 0.0 0.00021 20.6 0.0 1.8 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 EGR27871.1 - 0.00018 21.7 0.1 0.0018 18.4 0.1 2.7 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGR27871.1 - 0.0065 16.7 0.0 0.0065 16.7 0.0 2.3 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EGR27871.1 - 0.0065 16.9 1.0 0.011 16.1 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain Cytidylate_kin PF02224.18 EGR27871.1 - 0.0075 16.0 0.0 0.0075 16.0 0.0 2.6 3 0 0 3 3 3 1 Cytidylate kinase CPT PF07931.12 EGR27871.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Torsin PF06309.11 EGR27871.1 - 0.02 15.0 0.2 0.13 12.4 0.0 2.4 1 1 0 2 2 2 0 Torsin PAC4 PF16093.5 EGR27871.1 - 0.043 14.0 0.0 0.083 13.1 0.0 1.4 1 0 0 1 1 1 0 Proteasome assembly chaperone 4 CbiA PF01656.23 EGR27871.1 - 0.069 13.2 0.8 0.29 11.2 0.8 2.1 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain PRK PF00485.18 EGR27871.1 - 0.087 12.6 0.1 0.087 12.6 0.1 2.9 2 1 1 3 3 3 0 Phosphoribulokinase / Uridine kinase family LigD_N PF13298.6 EGR27871.1 - 0.32 11.3 3.6 0.79 10.0 2.2 2.4 2 1 0 2 2 2 0 DNA polymerase Ligase (LigD) Mito_carr PF00153.27 EGR27872.1 - 6.2e-107 349.8 11.7 6.9e-21 74.0 0.1 6.0 5 1 1 6 6 6 6 Mitochondrial carrier protein Ras PF00071.22 EGR27873.1 - 6.2e-52 175.5 3.1 1.2e-51 174.6 3.1 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR27873.1 - 8.6e-32 109.9 2.3 1e-31 109.6 0.7 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase CBS PF00571.28 EGR27873.1 - 2.5e-25 88.7 0.1 2.8e-09 37.3 0.1 4.1 4 0 0 4 4 4 3 CBS domain Arf PF00025.21 EGR27873.1 - 2.7e-17 62.8 0.3 5.6e-17 61.7 0.3 1.6 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR27873.1 - 4.8e-05 23.4 0.1 0.00017 21.7 0.1 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGR27873.1 - 0.0004 20.3 2.3 0.31 10.9 0.2 2.9 3 0 0 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 EGR27873.1 - 0.0066 16.0 0.6 0.011 15.2 0.6 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain TniB PF05621.11 EGR27873.1 - 0.065 12.6 0.5 2.2 7.7 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein DUF2535 PF10751.9 EGR27873.1 - 0.37 11.3 3.8 0.65 10.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2535) AAA_22 PF13401.6 EGR27873.1 - 0.76 10.0 3.6 2.5 8.4 0.1 2.9 3 1 0 3 3 3 0 AAA domain Ank_4 PF13637.6 EGR27874.1 - 7.3e-09 36.0 0.0 0.00093 19.7 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGR27874.1 - 1.2e-07 31.9 0.1 0.0042 17.4 0.0 2.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGR27874.1 - 6e-07 29.6 0.0 0.0034 17.8 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EGR27874.1 - 6.2e-05 23.5 0.0 0.00012 22.6 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGR27874.1 - 0.00049 20.3 0.3 0.68 10.7 0.0 3.2 3 1 0 3 3 3 2 Ankyrin repeat CcmH PF03918.14 EGR27875.1 - 5.8e-08 32.1 0.6 7.7e-08 31.7 0.6 1.2 1 0 0 1 1 1 1 Cytochrome C biogenesis protein MORN PF02493.20 EGR27876.1 - 1.6e-77 251.0 120.3 5.2e-08 32.3 1.3 15.3 15 0 0 15 15 15 15 MORN repeat Pkinase PF00069.25 EGR27877.1 - 2.4e-69 233.6 0.0 2.4e-69 233.6 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27877.1 - 1.1e-37 129.8 1.1 1.7e-37 129.2 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Tox-REase-9 PF15650.6 EGR27877.1 - 0.21 11.9 0.1 0.21 11.9 0.1 3.3 4 0 0 4 4 4 0 Restriction endonuclease fold toxin 9 Pkinase PF00069.25 EGR27878.1 - 8.1e-39 133.6 0.1 9.8e-39 133.3 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27878.1 - 4.9e-17 62.1 0.0 6.2e-17 61.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27878.1 - 3.2e-05 23.4 0.0 4.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 EGR27878.1 - 0.034 13.1 1.9 0.053 12.5 1.2 1.6 1 1 1 2 2 2 0 Poxvirus serine/threonine protein kinase Pkinase_fungal PF17667.1 EGR27878.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase MORN PF02493.20 EGR27879.1 - 1.6e-39 131.4 67.9 8.8e-06 25.3 0.8 10.0 10 0 0 10 10 10 9 MORN repeat DUF3048_C PF17479.2 EGR27879.1 - 0.11 12.9 17.1 4.1 7.8 0.2 4.9 1 1 4 5 5 5 0 Protein of unknown function (DUF3048) C-terminal domain Kri1_C PF12936.7 EGR27880.1 - 4.4e-23 81.3 2.2 4.4e-23 81.3 2.2 8.0 8 3 1 9 9 9 1 KRI1-like family C-terminal ZZ PF00569.17 EGR27880.1 - 0.014 15.2 8.1 0.014 15.2 8.1 3.0 3 0 0 3 3 3 0 Zinc finger, ZZ type FYVE PF01363.21 EGR27880.1 - 3.1 8.0 10.5 1.3e+02 2.8 10.5 2.6 1 1 0 1 1 1 0 FYVE zinc finger zf-UBR PF02207.20 EGR27880.1 - 3.5 7.9 15.3 2.2 8.5 4.4 2.7 1 1 1 2 2 2 0 Putative zinc finger in N-recognin (UBR box) MORN PF02493.20 EGR27881.1 - 5.6e-35 117.2 77.7 8.3e-06 25.4 1.7 13.4 13 1 0 13 13 13 11 MORN repeat Pkinase PF00069.25 EGR27882.1 - 2e-68 230.6 0.2 2.7e-68 230.2 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27882.1 - 4.3e-32 111.4 0.0 5.8e-32 111.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR27882.1 - 3.3e-05 22.8 0.0 7.1e-05 21.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR27882.1 - 0.00021 20.7 0.3 0.00064 19.1 0.3 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR27882.1 - 0.0013 18.7 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Prefoldin_2 PF01920.20 EGR27883.1 - 6.1e-08 32.6 8.5 8.1e-08 32.2 8.5 1.3 1 0 0 1 1 1 1 Prefoldin subunit Mod_r PF07200.13 EGR27883.1 - 0.55 10.3 9.7 0.45 10.6 6.9 2.0 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4407 PF14362.6 EGR27884.1 - 4.1 6.7 21.1 5.9 6.1 21.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BTG PF07742.12 EGR27884.1 - 9 6.2 14.8 2.5 8.0 7.4 2.6 1 1 2 3 3 3 0 BTG family GTP_EFTU PF00009.27 EGR27885.1 - 1.8e-40 138.6 0.0 1.8e-40 138.6 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGR27885.1 - 3.9e-09 36.8 3.5 2.2e-08 34.4 0.0 3.3 2 2 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EGR27885.1 - 7e-06 26.1 8.5 0.0017 18.4 0.0 4.0 3 1 0 3 3 3 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EGR27885.1 - 0.025 14.3 0.1 0.074 12.8 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4258 PF14076.6 EGR27885.1 - 0.18 12.2 1.7 10 6.6 0.3 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4258) Ribosomal_L21e PF01157.18 EGR27886.1 - 7.3e-41 138.1 4.1 7.3e-41 138.1 4.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e Spc7 PF08317.11 EGR27887.1 - 0.3 9.9 35.1 0.81 8.5 13.3 2.7 2 0 0 2 2 2 0 Spc7 kinetochore protein APG6_N PF17675.1 EGR27887.1 - 2.3 8.7 43.7 0.2 12.2 14.0 2.8 3 0 0 3 3 3 0 Apg6 coiled-coil region Fez1 PF06818.15 EGR27887.1 - 4 7.8 39.9 37 4.7 10.6 3.2 1 1 1 2 2 2 0 Fez1 DUF3015 PF11220.8 EGR27888.1 - 0.029 14.2 0.1 0.11 12.4 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) PRESAN PF09687.10 EGR27888.1 - 0.75 10.4 11.7 4.8 7.7 0.1 3.3 3 0 0 3 3 3 0 Plasmodium RESA N-terminal DLH PF01738.18 EGR27889.1 - 2.8e-45 154.5 0.2 3.4e-45 154.3 0.2 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Hydrolase_4 PF12146.8 EGR27889.1 - 0.00036 19.9 0.0 0.001 18.4 0.0 1.5 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGR27889.1 - 0.013 16.1 0.0 0.021 15.4 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGR27889.1 - 0.026 14.2 0.3 0.083 12.5 0.1 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase PF07224.11 EGR27889.1 - 0.043 12.8 0.0 0.058 12.4 0.0 1.1 1 0 0 1 1 1 0 Chlorophyllase PAF-AH_p_II PF03403.13 EGR27889.1 - 0.066 11.7 0.0 0.066 11.7 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II 14-3-3 PF00244.20 EGR27890.1 - 1.7e-71 240.2 15.3 7.5e-71 238.2 15.3 1.8 1 1 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 EGR27890.1 - 0.00016 21.9 0.4 0.87 9.9 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat Heme_oxygenase PF01126.20 EGR27890.1 - 0.016 15.0 2.0 0.074 12.8 0.6 2.5 1 1 0 2 2 2 0 Heme oxygenase HTH_50 PF18024.1 EGR27890.1 - 0.025 14.2 0.1 0.15 11.7 0.1 2.4 1 0 0 1 1 1 0 Helix-turn-helix domain TPR_8 PF13181.6 EGR27890.1 - 6.3 7.3 10.6 15 6.1 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat DNA_pol3_delta2 PF13177.6 EGR27891.1 - 2e-16 60.2 1.1 3.9e-16 59.2 0.1 2.0 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA PF00004.29 EGR27891.1 - 3e-14 53.6 0.1 2.2e-13 50.8 0.0 2.4 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EGR27891.1 - 4.8e-12 46.1 0.2 1e-11 45.0 0.2 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA_22 PF13401.6 EGR27891.1 - 4.6e-09 36.7 0.0 2.6e-08 34.2 0.0 2.1 2 1 0 2 2 2 1 AAA domain Rad17 PF03215.15 EGR27891.1 - 3.1e-07 30.5 0.1 8.2e-07 29.1 0.1 1.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EGR27891.1 - 1.6e-05 25.3 0.1 0.00072 20.0 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain AAA_11 PF13086.6 EGR27891.1 - 5.8e-05 23.0 0.7 0.00024 21.0 0.5 2.3 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EGR27891.1 - 0.0001 21.7 0.0 0.00023 20.5 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_assoc_2 PF16193.5 EGR27891.1 - 0.00019 21.7 0.0 0.00065 20.0 0.0 1.9 2 0 0 2 2 2 1 AAA C-terminal domain AAA_5 PF07728.14 EGR27891.1 - 0.00028 20.9 0.0 0.0008 19.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) ResIII PF04851.15 EGR27891.1 - 0.0003 20.9 0.1 0.0066 16.5 0.1 2.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_14 PF13173.6 EGR27891.1 - 0.00032 20.7 4.0 0.00074 19.6 0.3 3.1 2 2 1 3 3 3 1 AAA domain RuvB_N PF05496.12 EGR27891.1 - 0.0011 18.7 0.0 0.0039 16.9 0.0 1.9 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_30 PF13604.6 EGR27891.1 - 0.0027 17.5 0.0 0.0059 16.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EGR27891.1 - 0.0033 17.2 0.1 0.078 12.7 0.0 2.4 1 1 1 2 2 2 1 DEAD/DEAH box helicase DUF815 PF05673.13 EGR27891.1 - 0.0046 16.1 0.0 0.008 15.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 EGR27891.1 - 0.0092 16.5 0.3 0.73 10.3 0.0 2.7 2 1 0 2 2 2 1 ABC transporter AAA_24 PF13479.6 EGR27891.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGR27891.1 - 0.012 16.0 0.0 0.036 14.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EGR27891.1 - 0.028 14.3 0.0 0.7 9.8 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGR27891.1 - 0.032 14.6 0.1 0.14 12.6 0.1 2.2 1 1 0 1 1 1 0 RNA helicase Mg_chelatase PF01078.21 EGR27891.1 - 0.033 13.6 0.0 0.56 9.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TIP49_C PF17856.1 EGR27891.1 - 0.04 14.1 0.2 0.11 12.7 0.2 1.7 1 0 0 1 1 1 0 TIP49 AAA-lid domain AAA_28 PF13521.6 EGR27891.1 - 0.06 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DNA_pol3_gamma3 PF12169.8 EGR27891.1 - 0.078 12.9 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III subunits gamma and tau domain III Endonuc-MspI PF09208.10 EGR27891.1 - 0.089 12.2 4.9 0.49 9.7 1.5 2.6 2 1 0 2 2 2 0 Restriction endonuclease MspI IstB_IS21 PF01695.17 EGR27891.1 - 0.099 12.4 0.1 0.72 9.6 0.0 2.1 1 1 1 2 2 2 0 IstB-like ATP binding protein zf-CCHC PF00098.23 EGR27892.1 - 9e-05 22.4 18.9 0.015 15.3 3.8 2.4 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 EGR27892.1 - 0.0069 16.1 10.0 0.21 11.4 3.5 2.7 2 0 0 2 2 2 2 Zinc knuckle Amino_oxidase PF01593.24 EGR27893.1 - 4.1e-35 122.0 0.0 1.8e-12 47.3 0.0 3.0 1 1 2 3 3 3 3 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGR27893.1 - 2e-10 40.7 0.0 6.1e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGR27893.1 - 4.7e-06 26.4 0.0 7e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGR27893.1 - 6.6e-05 22.3 0.0 9.5e-05 21.8 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGR27893.1 - 9.5e-05 21.7 0.0 0.00025 20.4 0.0 1.7 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.24 EGR27893.1 - 0.0015 17.7 0.0 0.0022 17.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_9 PF13454.6 EGR27893.1 - 0.0028 17.7 0.0 0.0081 16.2 0.0 1.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EGR27893.1 - 0.0083 14.9 0.1 0.042 12.5 0.0 2.1 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_3 PF01494.19 EGR27893.1 - 0.027 13.7 0.0 1 8.5 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain FAD_oxidored PF12831.7 EGR27893.1 - 0.037 13.4 0.0 0.14 11.5 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGR27893.1 - 0.043 14.4 0.0 0.1 13.2 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGR27893.1 - 0.075 12.1 0.3 0.36 9.8 0.0 2.1 3 0 0 3 3 3 0 Glucose inhibited division protein A Pkinase PF00069.25 EGR27894.1 - 1.2e-74 251.0 2.2 1.2e-74 251.0 2.2 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27894.1 - 3.5e-43 147.8 0.4 7.3e-43 146.7 0.4 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27894.1 - 5.1e-13 49.0 0.4 5.1e-13 49.0 0.4 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGR27894.1 - 2.6e-06 26.9 0.5 6.9e-06 25.6 0.3 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR27894.1 - 0.00051 18.9 0.0 0.0008 18.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase EF-hand_6 PF13405.6 EGR27894.1 - 0.00058 19.6 7.8 0.26 11.3 0.1 4.9 5 0 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 EGR27894.1 - 0.0041 16.6 4.1 0.8 9.4 0.1 4.2 4 0 0 4 4 4 1 EF hand APH PF01636.23 EGR27894.1 - 0.0045 16.9 0.0 0.0095 15.9 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family EF-hand_7 PF13499.6 EGR27894.1 - 0.032 14.7 3.9 2.2 8.8 0.2 3.5 2 1 1 3 3 3 0 EF-hand domain pair FTA2 PF13095.6 EGR27894.1 - 0.079 12.6 8.5 0.24 11.0 0.0 3.3 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 EF-hand_14 PF17959.1 EGR27894.1 - 0.14 12.5 10.1 2 8.8 0.4 4.5 2 1 2 4 4 4 0 EF-hand domain DNA_pol_B_thumb PF14791.6 EGR27894.1 - 0.15 12.2 0.0 0.37 11.0 0.0 1.6 1 0 0 1 1 1 0 DNA polymerase beta thumb Aminotran_1_2 PF00155.21 EGR27896.1 - 6.8e-25 88.0 0.0 7.4e-25 87.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_1_2 PF00155.21 EGR27897.1 - 4.3e-10 39.3 0.0 5.2e-10 39.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II EF-hand_6 PF13405.6 EGR27898.1 - 0.0079 16.0 8.7 0.017 15.0 0.0 3.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 EGR27898.1 - 0.025 14.1 0.1 0.025 14.1 0.1 3.5 4 0 0 4 4 4 0 EF hand EF-hand_7 PF13499.6 EGR27898.1 - 0.034 14.6 2.3 0.11 13.0 1.2 2.3 2 0 0 2 2 2 0 EF-hand domain pair DENN PF02141.21 EGR27899.1 - 1.9e-34 119.2 2.8 1.9e-34 119.2 2.8 2.1 2 0 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 EGR27899.1 - 6.1e-18 65.3 0.8 1.5e-17 64.1 0.8 1.7 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 EGR27899.1 - 2.8e-06 27.2 0.5 1e-05 25.4 0.5 2.1 1 0 0 1 1 1 1 dDENN domain EF-hand_7 PF13499.6 EGR27900.1 - 8.2e-11 42.2 1.1 8.2e-11 42.2 1.1 3.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EGR27900.1 - 2.4e-09 36.1 4.6 2.2e-05 23.7 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EGR27900.1 - 6.4e-08 32.3 5.6 1.4e-07 31.2 1.1 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR27900.1 - 2.9e-07 29.9 4.3 0.0077 16.1 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 EGR27900.1 - 0.016 14.6 0.3 8.7 6.0 0.0 2.8 2 0 0 2 2 2 0 EF hand EFhand_Ca_insen PF08726.10 EGR27900.1 - 0.058 13.5 3.8 0.31 11.2 0.5 3.0 2 1 1 3 3 3 0 Ca2+ insensitive EF hand SPARC_Ca_bdg PF10591.9 EGR27900.1 - 2.6 8.4 11.2 1.2 9.5 6.8 2.6 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region RRF PF01765.19 EGR27901.1 - 8e-36 123.4 12.5 9.4e-36 123.2 12.5 1.0 1 0 0 1 1 1 1 Ribosome recycling factor HutP PF09021.11 EGR27901.1 - 0.0033 17.7 0.5 0.006 16.9 0.5 1.4 1 0 0 1 1 1 1 HutP SSURE PF11966.8 EGR27901.1 - 0.036 13.8 1.2 6.5 6.6 0.1 2.5 2 0 0 2 2 2 0 Fibronectin-binding repeat EH_Signature PF15611.6 EGR27901.1 - 0.081 12.3 0.2 0.085 12.3 0.2 1.1 1 0 0 1 1 1 0 EH_Signature domain Mitofilin PF09731.9 EGR27901.1 - 0.19 10.5 11.5 0.19 10.5 11.5 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein V-ATPase_H_C PF11698.8 EGR27901.1 - 7.1 6.8 9.4 5.7 7.1 1.0 2.3 1 1 0 2 2 2 0 V-ATPase subunit H Nbl1_Borealin_N PF10444.9 EGR27901.1 - 7.5 6.3 8.5 0.16 11.6 0.8 2.3 4 0 0 4 4 4 0 Nbl1 / Borealin N terminal AAA_28 PF13521.6 EGR27902.1 - 4.7e-23 82.2 0.0 9e-23 81.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain UCH PF00443.29 EGR27902.1 - 1.3e-08 34.6 0.8 1.3e-08 34.6 0.8 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Thymidylate_kin PF02223.17 EGR27902.1 - 9.8e-06 25.4 0.1 9.8e-06 25.4 0.1 2.2 3 0 0 3 3 3 1 Thymidylate kinase UCH_1 PF13423.6 EGR27902.1 - 0.0023 17.6 0.1 0.0023 17.6 0.1 3.1 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Thioredoxin PF00085.20 EGR27903.1 - 7.7e-51 170.4 1.8 7.2e-31 106.2 0.0 2.9 2 1 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EGR27903.1 - 8.6e-07 29.4 4.0 0.018 15.5 0.3 4.4 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_6 PF13848.6 EGR27903.1 - 3.9e-05 23.6 0.7 0.1 12.5 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EGR27903.1 - 6.3e-05 23.1 0.0 0.23 11.7 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like OST3_OST6 PF04756.13 EGR27903.1 - 0.0014 18.0 0.5 0.22 10.8 0.0 3.1 3 0 0 3 3 3 1 OST3 / OST6 family, transporter family DIM1 PF02966.16 EGR27903.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 0 Mitosis protein DIM1 DUF4834 PF16118.5 EGR27903.1 - 6.2 7.9 6.8 9.4 7.3 0.9 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) GTP_cyclohydroI PF01227.22 EGR27904.1 - 1.6e-58 197.1 0.1 1.9e-58 196.8 0.1 1.0 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EGR27904.1 - 0.021 15.0 0.0 0.036 14.2 0.0 1.4 1 0 0 1 1 1 0 QueF-like protein Pribosyltran_N PF13793.6 EGR27905.1 - 6.6e-48 161.5 0.1 2.6e-47 159.6 0.0 1.9 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyltran PF00156.27 EGR27905.1 - 5e-08 32.6 0.1 3.2e-07 30.0 0.1 2.3 4 0 0 4 4 4 1 Phosphoribosyl transferase domain Pribosyl_synth PF14572.6 EGR27905.1 - 0.00012 22.2 0.7 0.00046 20.3 0.6 1.9 1 1 1 2 2 2 1 Phosphoribosyl synthetase-associated domain AFP_2 PF18815.1 EGR27906.1 - 0.045 14.0 15.5 0.31 11.3 5.9 2.8 2 0 0 2 2 2 0 Bacterial antifreeze protein repeat Pkinase PF00069.25 EGR27909.1 - 3.7e-25 88.8 0.1 4.4e-25 88.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27909.1 - 2e-14 53.5 0.0 2.1e-14 53.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR27909.1 - 2.1e-08 33.3 0.0 3e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR27909.1 - 0.07 13.0 0.0 0.62 9.9 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family Vps26 PF03643.15 EGR27910.1 - 4e-21 75.2 2.4 2.3e-20 72.8 1.5 2.1 1 1 1 2 2 2 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EGR27910.1 - 0.0081 16.2 0.7 0.56 10.2 0.0 3.1 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain QueF PF14489.6 EGR27911.1 - 0.062 13.5 0.5 0.1 12.8 0.5 1.4 1 0 0 1 1 1 0 QueF-like protein FAA_hydrolase PF01557.18 EGR27912.1 - 4.6e-36 124.5 0.0 7.4e-36 123.9 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EGR27912.1 - 7e-28 96.9 0.0 2.8e-27 95.0 0.0 1.8 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal CCDC142 PF14923.6 EGR27912.1 - 0.0034 16.2 0.1 0.0046 15.8 0.1 1.1 1 0 0 1 1 1 1 Coiled-coil protein 142 FAA_hydrolase PF01557.18 EGR27913.1 - 5e-07 29.6 0.1 5.4e-07 29.5 0.1 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF4941 PF16299.5 EGR27913.1 - 0.049 12.9 0.0 0.055 12.8 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4941) EF-hand_1 PF00036.32 EGR27914.1 - 1.4e-16 58.7 6.4 0.00021 20.6 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGR27914.1 - 6.6e-15 55.3 4.5 4.1e-08 33.6 0.5 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR27914.1 - 2.9e-11 42.3 5.0 0.027 14.4 0.2 4.5 3 2 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGR27914.1 - 8.3e-11 41.6 6.5 3e-06 27.0 0.4 3.5 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EGR27914.1 - 9e-06 25.0 3.6 0.0068 15.9 0.1 3.8 3 1 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 EGR27914.1 - 0.00011 22.5 0.1 0.047 14.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain DUF2420 PF10336.9 EGR27914.1 - 0.046 13.7 0.5 0.095 12.7 0.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2420) GPHH PF16905.5 EGR27914.1 - 0.081 12.7 0.0 47 3.9 0.0 3.1 3 0 0 3 3 3 0 Voltage-dependent L-type calcium channel, IQ-associated SASRP1 PF15160.6 EGR27916.1 - 7.9e-06 25.7 0.1 1.2e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Spermatogenesis-associated serine-rich protein 1 MORN PF02493.20 EGR27917.1 - 2.8e-56 184.1 85.4 1.1e-07 31.3 1.8 10.4 10 0 0 10 10 10 10 MORN repeat DUF2760 PF10816.8 EGR27917.1 - 0.037 13.9 0.4 0.067 13.0 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2760) cNMP_binding PF00027.29 EGR27919.1 - 0.06 13.4 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Sp38 PF07354.12 EGR27919.1 - 0.1 12.0 1.1 0.13 11.7 1.1 1.1 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) CK_II_beta PF01214.18 EGR27920.1 - 1.6e-17 63.9 0.5 1.8e-17 63.7 0.5 1.1 1 0 0 1 1 1 1 Casein kinase II regulatory subunit PP2C PF00481.21 EGR27921.1 - 5.6e-63 213.0 0.0 6.4e-63 212.8 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C NTP_transferase PF00483.23 EGR27923.1 - 3.4e-25 89.0 0.1 1.4e-21 77.2 0.0 2.2 1 1 1 2 2 2 2 Nucleotidyl transferase Hexapep PF00132.24 EGR27923.1 - 1.1e-10 40.7 7.5 1.5e-07 30.8 0.9 3.6 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EGR27923.1 - 9.4e-07 29.3 0.0 1.2e-06 28.9 0.0 1.1 1 0 0 1 1 1 1 MobA-like NTP transferase domain Fucokinase PF07959.12 EGR27923.1 - 0.0012 17.9 1.9 0.015 14.3 1.9 2.0 1 1 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 EGR27923.1 - 0.0042 15.3 1.9 0.006 14.8 1.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) IspD PF01128.19 EGR27923.1 - 0.0064 16.3 0.0 0.0098 15.7 0.0 1.3 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Hexapep_2 PF14602.6 EGR27923.1 - 0.0096 15.7 8.7 0.024 14.4 3.8 3.1 2 1 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase PAS_9 PF13426.7 EGR27924.1 - 0.0001 22.5 9.8 0.034 14.4 0.0 4.2 4 0 0 4 4 4 2 PAS domain PAS PF00989.25 EGR27924.1 - 0.014 15.4 2.0 1.9 8.5 0.0 3.6 4 0 0 4 4 4 0 PAS fold Cadherin_C_2 PF16492.5 EGR27924.1 - 0.029 15.1 3.3 0.92 10.3 0.2 3.4 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal CPG4 PF15481.6 EGR27924.1 - 2.6 8.7 6.6 3.7 8.3 0.6 3.5 3 0 0 3 3 3 0 Chondroitin proteoglycan 4 RIH_assoc PF08454.11 EGR27925.1 - 1.3e-27 95.6 8.0 1.3e-27 95.6 8.0 11.0 8 2 1 9 9 9 1 RyR and IP3R Homology associated Ins145_P3_rec PF08709.11 EGR27925.1 - 3.7e-18 65.5 0.5 3.7e-18 65.5 0.5 2.2 2 0 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 EGR27925.1 - 8.4e-09 35.5 12.7 1.9e-08 34.4 0.2 4.4 3 0 0 3 3 3 2 MIR domain RYDR_ITPR PF01365.21 EGR27925.1 - 3.6e-06 26.6 13.1 3.6e-06 26.6 13.1 8.6 7 3 1 8 8 8 2 RIH domain PerC PF06069.11 EGR27925.1 - 0.043 14.1 0.2 4.4 7.6 0.3 4.2 3 0 0 3 3 3 0 PerC transcriptional activator Ion_trans PF00520.31 EGR27925.1 - 0.047 12.9 7.2 0.3 10.3 7.2 2.5 1 1 0 1 1 1 0 Ion transport protein Copine PF07002.16 EGR27926.1 - 1.6e-36 125.9 0.1 2.7e-36 125.1 0.1 1.4 1 0 0 1 1 1 1 Copine C2 PF00168.30 EGR27926.1 - 7.8e-10 39.0 2.3 2.1e-07 31.1 0.5 3.2 2 1 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EGR27926.1 - 0.0092 16.1 0.2 0.027 14.6 0.0 1.9 2 0 0 2 2 2 1 vWA found in TerF C terminus ZIP4_domain PF18292.1 EGR27928.1 - 1.1 9.1 7.7 2.5 8.0 7.7 1.5 1 1 0 1 1 1 0 Zinc transporter ZIP4 domain NOA36 PF06524.12 EGR27928.1 - 4.8 6.4 12.5 7.3 5.8 12.5 1.3 1 0 0 1 1 1 0 NOA36 protein MDM10 PF12519.8 EGR27929.1 - 6.6 5.5 35.5 7.7 5.2 35.5 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF3285 PF11688.8 EGR27930.1 - 0.85 9.6 4.1 0.48 10.4 1.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3285) CAF1 PF04857.20 EGR27931.1 - 1.9e-09 37.2 6.1 3.1e-09 36.4 6.1 1.3 1 1 0 1 1 1 1 CAF1 family ribonuclease Lac_bphage_repr PF06543.12 EGR27931.1 - 0.093 12.7 0.3 0.17 11.9 0.3 1.4 1 0 0 1 1 1 0 Lactococcus bacteriophage repressor Tim17 PF02466.19 EGR27932.1 - 3.5e-08 33.8 0.9 5.2e-08 33.2 1.0 1.3 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family HEAT PF02985.22 EGR27934.1 - 1.8e-16 58.8 0.0 0.081 13.2 0.0 8.5 9 0 0 9 9 9 5 HEAT repeat HEAT_2 PF13646.6 EGR27934.1 - 2.5e-10 40.6 0.0 0.026 14.9 0.0 5.7 3 2 3 6 6 6 2 HEAT repeats RTP1_C1 PF10363.9 EGR27934.1 - 5.6e-05 23.3 1.8 1.4 9.1 0.0 4.5 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 IFRD PF05004.13 EGR27934.1 - 7.7e-05 21.9 0.1 0.049 12.7 0.0 3.6 2 1 2 4 4 4 1 Interferon-related developmental regulator (IFRD) TAF6_C PF07571.13 EGR27934.1 - 0.0017 18.7 0.3 58 4.1 0.0 4.8 4 1 0 5 5 5 0 TAF6 C-terminal HEAT repeat domain CLASP_N PF12348.8 EGR27934.1 - 0.0032 17.1 10.2 3.6 7.1 0.0 4.9 3 3 1 4 4 4 1 CLASP N terminal HEAT_EZ PF13513.6 EGR27934.1 - 0.017 15.6 0.0 0.37 11.3 0.0 3.1 3 0 0 3 3 3 0 HEAT-like repeat GHL15 PF14885.6 EGR27934.1 - 0.13 12.2 0.1 0.31 11.0 0.1 1.6 1 0 0 1 1 1 0 Hypothetical glycosyl hydrolase family 15 Acetyltransf_9 PF13527.7 EGR27934.1 - 0.15 12.2 0.0 6.7 6.8 0.0 2.7 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF2283 PF10049.9 EGR27934.1 - 1.5 9.2 4.2 37 4.7 0.0 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2283) Vac14_Fab1_bd PF12755.7 EGR27934.1 - 3.6 8.2 12.8 12 6.5 0.0 5.9 3 2 5 8 8 8 0 Vacuolar 14 Fab1-binding region MFS_1 PF07690.16 EGR27936.1 - 2.2e-16 59.8 18.6 2.4e-16 59.6 6.4 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGR27936.1 - 1.2e-11 44.2 13.5 1.4e-11 43.9 4.3 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter Ssu72 PF04722.13 EGR27937.1 - 0.0096 15.5 0.1 0.011 15.3 0.1 1.0 1 0 0 1 1 1 1 Ssu72-like protein DUF5635 PF18685.1 EGR27937.1 - 0.085 12.8 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5635) Pkinase PF00069.25 EGR27938.1 - 6.2e-62 209.3 4.1 8.6e-62 208.9 4.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27938.1 - 3e-43 148.0 1.5 3e-43 148.0 1.5 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EGR27938.1 - 2.1e-05 24.0 0.3 5.5e-05 22.6 0.2 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGR27938.1 - 0.00017 21.0 0.1 0.00046 19.6 0.1 1.7 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGR27938.1 - 0.00019 21.1 7.1 0.00036 20.2 1.4 3.2 3 1 1 4 4 4 1 RIO1 family APH PF01636.23 EGR27938.1 - 0.00041 20.3 0.0 0.0017 18.3 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGR27938.1 - 0.0032 16.5 5.9 0.0075 15.2 5.9 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGR27938.1 - 0.072 11.8 0.1 0.12 11.1 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase Ion_trans_2 PF07885.16 EGR27939.1 - 3.1e-06 27.1 0.6 5.6e-06 26.2 0.6 1.4 1 0 0 1 1 1 1 Ion channel Fib_alpha PF08702.10 EGR27939.1 - 0.044 14.0 1.6 0.067 13.4 1.6 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family cNMP_binding PF00027.29 EGR27939.1 - 0.072 13.2 0.1 0.14 12.2 0.1 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Malectin PF11721.8 EGR27941.1 - 4.9e-39 134.1 7.4 1e-38 133.0 7.4 1.6 1 0 0 1 1 1 1 Malectin domain DBR1 PF05011.13 EGR27941.1 - 6.2e-14 52.6 0.4 1.7e-13 51.2 0.0 1.9 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain UCH PF00443.29 EGR27942.1 - 2.4e-43 148.5 10.0 2.4e-43 148.5 10.0 4.1 4 2 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR27942.1 - 1.7e-30 106.7 12.5 1.7e-30 106.7 12.5 3.2 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_2 PF14560.6 EGR27942.1 - 6.4e-05 23.3 0.1 0.00021 21.7 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin-like domain cNMP_binding PF00027.29 EGR27943.1 - 6.1e-18 64.7 0.1 1.2e-17 63.8 0.1 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGR27943.1 - 4.7e-12 45.7 4.9 4.7e-12 45.7 4.9 2.0 2 0 0 2 2 2 1 Ion channel FeThRed_B PF02943.15 EGR27943.1 - 0.021 14.8 0.6 0.059 13.4 0.1 2.0 2 0 0 2 2 2 0 Ferredoxin thioredoxin reductase catalytic beta chain Glycos_transf_2 PF00535.26 EGR27944.1 - 7.1e-34 117.1 0.0 8.8e-34 116.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGR27944.1 - 4.2e-13 49.7 0.0 5.2e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 EGR27944.1 - 4e-05 23.2 0.0 0.00021 20.9 0.0 1.9 1 1 1 2 2 2 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGR27944.1 - 0.0048 16.4 0.0 0.0078 15.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 DUF1870 PF08965.10 EGR27945.1 - 0.27 11.3 0.1 0.27 11.3 0.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1870) zf-SNAP50_C PF12251.8 EGR27946.1 - 1.3e-36 126.2 13.1 1.6e-36 125.8 13.1 1.1 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal PP2C PF00481.21 EGR27946.1 - 1.5e-17 64.1 0.0 2.4e-17 63.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C CEBP_ZZ PF16366.5 EGR27946.1 - 4.8 7.5 8.7 0.64 10.3 3.2 2.4 3 1 0 3 3 3 0 Cytoplasmic polyadenylation element-binding protein ZZ domain Inositol_P PF00459.25 EGR27947.1 - 8.8e-35 120.5 0.0 1.1e-34 120.2 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family DUF5494 PF17598.2 EGR27948.1 - 0.92 9.7 5.4 0.19 11.9 0.9 1.9 1 1 1 2 2 2 0 Family of unknown function (DUF5494) DUF5113 PF17140.4 EGR27948.1 - 2.9 7.7 9.7 0.069 13.0 2.7 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) Pkinase PF00069.25 EGR27949.1 - 4.3e-50 170.5 1.1 6.9e-43 146.9 0.1 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27949.1 - 2.4e-27 95.8 1.0 7.5e-23 81.1 0.1 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR27949.1 - 1.8e-05 23.9 1.2 5.4e-05 22.3 1.2 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGR27949.1 - 0.0003 20.2 0.1 0.0017 17.8 0.0 1.9 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 EGR27949.1 - 0.0014 18.3 1.6 0.5 10.0 0.4 2.1 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGR27949.1 - 0.0053 15.6 0.0 0.009 14.8 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGR27949.1 - 0.016 14.6 0.1 0.023 14.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ets PF00178.22 EGR27949.1 - 0.032 14.7 0.3 0.15 12.5 0.3 2.1 2 0 0 2 2 2 0 Ets-domain DUF3933 PF13069.6 EGR27949.1 - 0.15 12.0 0.4 0.36 10.7 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3933) DUF4200 PF13863.6 EGR27950.1 - 3.2e-19 69.5 25.4 3.2e-19 69.5 25.4 5.3 3 1 1 4 4 4 1 Domain of unknown function (DUF4200) TAL_FSA PF00923.19 EGR27951.1 - 4.8e-70 236.1 0.4 6.7e-70 235.7 0.4 1.1 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DUF2434 PF10361.9 EGR27952.1 - 0.0024 16.9 0.1 0.003 16.6 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2434) FH2 PF02181.23 EGR27953.1 - 3.2e-66 224.0 13.0 3.2e-66 224.0 13.0 1.6 3 0 0 3 3 3 1 Formin Homology 2 Domain DUF1351 PF07083.11 EGR27953.1 - 2.3 7.9 29.0 0.017 14.9 19.0 2.5 3 1 0 3 3 3 0 Protein of unknown function (DUF1351) Kelch_6 PF13964.6 EGR27955.1 - 0.00045 20.4 0.0 0.048 14.0 0.0 2.5 2 0 0 2 2 2 1 Kelch motif Kelch_5 PF13854.6 EGR27955.1 - 0.0011 18.9 0.2 0.0044 17.0 0.0 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.6 EGR27955.1 - 0.0034 17.3 0.0 1.6 8.8 0.0 2.3 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_3 PF13415.6 EGR27955.1 - 0.13 12.6 0.0 25 5.3 0.0 2.4 2 0 0 2 2 2 0 Galactose oxidase, central domain Pkinase PF00069.25 EGR27956.1 - 1.3e-46 159.2 2.2 1.6e-46 158.8 2.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27956.1 - 4.9e-24 85.0 0.3 6.1e-24 84.7 0.3 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27956.1 - 1.2e-05 24.8 0.0 2e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EGR27956.1 - 2.5e-05 23.5 1.3 3.2e-05 23.1 0.3 1.6 1 1 0 1 1 1 1 Seadornavirus VP7 Pkinase_fungal PF17667.1 EGR27956.1 - 8.1e-05 21.6 0.0 0.00012 21.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGR27956.1 - 0.0039 16.2 4.0 0.0052 15.8 4.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain YrbL-PhoP_reg PF10707.9 EGR27956.1 - 0.01 15.4 0.6 0.016 14.8 0.6 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 EGR27956.1 - 0.28 11.1 0.0 0.36 10.7 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ras PF00071.22 EGR27957.1 - 3.4e-47 160.1 0.0 4e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR27957.1 - 5.6e-31 107.2 0.1 1e-30 106.4 0.0 1.4 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR27957.1 - 1.4e-12 47.4 0.1 1.7e-12 47.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR27957.1 - 0.00012 22.1 0.1 0.00021 21.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGR27957.1 - 0.00065 19.0 0.3 0.13 11.4 0.1 2.5 2 1 1 3 3 3 1 G-protein alpha subunit SRPRB PF09439.10 EGR27957.1 - 0.0016 17.9 0.0 0.0023 17.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGR27957.1 - 0.0075 15.6 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EGR27957.1 - 0.01 15.6 0.0 0.02 14.7 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.22 EGR27957.1 - 0.011 16.1 0.2 0.46 10.9 0.2 2.2 1 1 0 1 1 1 0 RNA helicase RsgA_GTPase PF03193.16 EGR27957.1 - 0.017 15.1 0.1 0.33 10.8 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase MCM PF00493.23 EGR27957.1 - 0.021 13.9 0.0 0.071 12.2 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain Septin PF00735.18 EGR27957.1 - 0.032 13.5 0.1 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 Septin AAA_24 PF13479.6 EGR27957.1 - 0.045 13.5 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EGR27957.1 - 0.066 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_7 PF12775.7 EGR27957.1 - 0.071 12.6 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 EGR27957.1 - 0.097 12.4 0.4 8.4 6.1 0.3 2.2 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EGR27957.1 - 0.1 12.1 0.1 0.28 10.7 0.0 1.7 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain NTPase_1 PF03266.15 EGR27957.1 - 0.13 12.1 0.2 0.27 11.1 0.2 1.5 1 0 0 1 1 1 0 NTPase TsaE PF02367.17 EGR27957.1 - 0.14 12.2 0.0 0.31 11.1 0.1 1.5 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRF-TF PF00319.18 EGR27957.1 - 7.6 6.1 7.9 3.9 7.0 1.1 3.0 3 0 0 3 3 3 0 SRF-type transcription factor (DNA-binding and dimerisation domain) Gti1_Pac2 PF09729.9 EGR27958.1 - 0.7 10.0 8.4 0.73 9.9 8.4 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family Zip PF02535.22 EGR27958.1 - 0.81 8.8 6.9 0.84 8.8 6.9 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter DNA_pol_phi PF04931.13 EGR27958.1 - 4.5 5.2 25.0 5 5.1 25.0 1.0 1 0 0 1 1 1 0 DNA polymerase phi ANAPC4_WD40 PF12894.7 EGR27959.1 - 4.4e-17 62.2 0.8 0.00087 19.5 0.0 5.5 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGR27959.1 - 1.6e-12 47.7 0.0 0.015 16.2 0.0 6.1 6 0 0 6 6 6 2 WD domain, G-beta repeat eIF2A PF08662.11 EGR27959.1 - 3.4e-09 36.9 11.0 0.0012 18.8 0.1 4.9 1 1 4 5 5 5 5 Eukaryotic translation initiation factor eIF2A TTL PF03133.15 EGR27960.1 - 2.7e-36 125.2 1.8 2.7e-36 125.2 1.8 4.0 2 1 3 5 5 5 1 Tubulin-tyrosine ligase family SHIPPO-rpt PF07004.12 EGR27961.1 - 2.4e-06 28.2 5.3 0.51 11.4 0.0 4.5 4 0 0 4 4 4 3 Sperm-tail PG-rich repeat SMC_hinge PF06470.13 EGR27961.1 - 0.15 12.4 0.1 0.3 11.4 0.1 1.4 1 0 0 1 1 1 0 SMC proteins Flexible Hinge Domain Ion_trans_2 PF07885.16 EGR27961.1 - 3.2 7.8 8.0 1.9 8.5 5.2 2.1 2 0 0 2 2 2 0 Ion channel Phe_ZIP PF08916.11 EGR27961.1 - 3.9 8.3 6.6 21 5.9 0.1 3.3 3 0 0 3 3 3 0 Phenylalanine zipper MORN PF02493.20 EGR27963.1 - 7.4e-57 186.0 71.8 5.1e-08 32.3 1.7 10.6 11 0 0 11 11 11 10 MORN repeat LAP1C PF05609.12 EGR27964.1 - 0.42 9.7 73.2 0.65 9.0 73.2 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SWI-SNF_Ssr4 PF08549.10 EGR27964.1 - 1.4 7.4 64.7 1.7 7.2 64.7 1.1 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) Lipid_DES PF08557.10 EGR27965.1 - 0.074 12.6 0.3 0.17 11.4 0.3 1.6 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) Pkinase PF00069.25 EGR27966.1 - 7.9e-34 117.2 0.3 9.6e-34 116.9 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27966.1 - 1.4e-22 80.2 0.1 1.9e-22 79.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR27966.1 - 4.9e-05 22.4 0.4 6.7e-05 22.0 0.4 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGR27966.1 - 0.0017 17.7 0.2 0.0021 17.4 0.2 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR27966.1 - 0.008 15.6 0.1 0.011 15.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGR27966.1 - 0.016 14.8 0.5 0.022 14.3 0.5 1.2 1 0 0 1 1 1 0 RIO1 family DUF3933 PF13069.6 EGR27966.1 - 0.14 12.0 0.6 0.43 10.5 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3933) Skp1_POZ PF03931.15 EGR27967.1 - 0.004 17.3 0.1 0.011 15.9 0.1 1.7 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Phage_TAC_4 PF08748.11 EGR27967.1 - 0.0078 16.5 0.3 0.017 15.4 0.3 1.9 1 1 0 1 1 1 1 Phage tail assembly chaperone TBCA PF02970.16 EGR27967.1 - 0.012 16.0 3.9 0.028 14.8 3.9 1.6 1 0 0 1 1 1 0 Tubulin binding cofactor A Tash_PEST PF07708.11 EGR27967.1 - 0.015 15.5 1.6 0.044 14.0 1.6 1.9 1 0 0 1 1 1 0 Tash protein PEST motif DUF596 PF04591.12 EGR27967.1 - 0.11 12.6 0.2 4.1 7.6 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function, DUF596 PP2C PF00481.21 EGR27968.1 - 2.8e-60 204.1 0.1 5.4e-60 203.2 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C FHA PF00498.26 EGR27968.1 - 1.4e-06 28.5 0.4 0.00033 20.9 0.5 3.4 2 1 0 2 2 2 1 FHA domain PP2C_2 PF13672.6 EGR27968.1 - 8.3e-06 25.6 0.0 1.3e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Yop-YscD_cpl PF16697.5 EGR27968.1 - 0.0016 18.7 0.0 0.17 12.2 0.0 3.1 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain WD40 PF00400.32 EGR27969.1 - 3.3e-14 53.1 0.0 0.0019 19.0 0.0 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat UTP15_C PF09384.10 EGR27969.1 - 4.4e-13 49.2 2.0 8.9e-13 48.2 2.0 1.5 1 0 0 1 1 1 1 UTP15 C terminal ANAPC4_WD40 PF12894.7 EGR27969.1 - 2.1e-12 47.2 0.0 0.00088 19.5 0.0 4.7 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGR27969.1 - 8.9e-08 32.1 0.2 0.029 14.4 0.0 4.2 2 1 3 5 5 5 3 Ciliary BBSome complex subunit 2, middle region WD40_like PF17005.5 EGR27969.1 - 0.00016 21.2 3.8 0.0051 16.2 0.5 2.7 1 1 1 2 2 2 2 WD40-like domain DUF4354 PF14263.6 EGR27969.1 - 0.16 11.8 3.0 2.7 7.8 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4354) Yip1 PF04893.17 EGR27970.1 - 1.1e-14 54.5 9.3 1.5e-14 54.1 9.3 1.1 1 0 0 1 1 1 1 Yip1 domain SHIPPO-rpt PF07004.12 EGR27971.1 - 0.0005 20.9 15.6 16 6.6 0.1 6.8 6 0 0 6 6 6 4 Sperm-tail PG-rich repeat NB-ARC PF00931.22 EGR27971.1 - 0.039 13.1 0.0 0.077 12.2 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Pkinase PF00069.25 EGR27972.1 - 1.7e-22 80.0 1.2 5.1e-22 78.5 1.2 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR27972.1 - 5.7e-17 61.8 0.5 1e-16 61.0 0.5 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR27972.1 - 0.018 15.0 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ATP-synt_ab_Xtn PF16886.5 EGR27972.1 - 0.37 10.7 4.9 1.9 8.3 0.1 3.5 1 1 0 2 2 2 0 ATPsynthase alpha/beta subunit N-term extension Pkinase PF00069.25 EGR27973.1 - 7.6e-62 209.1 1.2 7.6e-62 209.1 1.2 2.1 2 0 0 2 2 2 1 Protein kinase domain cNMP_binding PF00027.29 EGR27973.1 - 9.8e-32 108.9 1.6 1.6e-15 57.0 0.0 3.6 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 EGR27973.1 - 1.6e-28 99.7 0.1 3.2e-28 98.7 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR27973.1 - 4.3e-07 29.5 0.9 1.2e-06 28.1 0.9 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR27973.1 - 2.5e-06 26.5 0.0 4.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase DUF2368 PF10166.9 EGR27973.1 - 0.16 11.6 2.6 0.2 11.3 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2368) Ribosomal_S8e PF01201.22 EGR27973.1 - 0.72 10.0 4.3 0.18 11.9 0.6 1.9 2 0 0 2 2 2 0 Ribosomal protein S8e RhoGEF67_u2 PF16614.5 EGR27974.1 - 4.1 7.5 6.1 4.2 7.5 5.1 1.6 1 1 0 1 1 1 0 Unstructured region two on RhoGEF 6 and 7 YqfQ PF14181.6 EGR27975.1 - 2.7 8.1 9.1 1.5 9.0 7.8 1.4 1 1 0 1 1 1 0 YqfQ-like protein ApoO PF09769.9 EGR27976.1 - 0.013 15.5 7.5 0.053 13.5 1.5 2.8 2 0 0 2 2 2 0 Apolipoprotein O CALCOCO1 PF07888.11 EGR27976.1 - 0.71 8.7 38.5 0.4 9.5 2.7 2.2 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Ins145_P3_rec PF08709.11 EGR27977.1 - 3e-13 49.5 13.4 4.2e-13 49.0 4.4 2.8 1 1 1 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 EGR27977.1 - 0.0008 19.3 0.3 0.0008 19.3 0.3 3.8 4 0 0 4 4 4 2 MIR domain DUF4342 PF14242.6 EGR27977.1 - 0.31 11.1 6.1 1.2 9.1 2.7 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) DUF4149 PF13664.6 EGR27978.1 - 2.6 8.4 7.9 0.26 11.6 0.3 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4149) NAD_binding_2 PF03446.15 EGR27979.1 - 9.4e-43 146.1 0.1 1.4e-42 145.5 0.1 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EGR27979.1 - 1.6e-33 115.6 0.0 2.7e-33 114.8 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EGR27979.1 - 9.4e-08 32.5 0.0 4e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EGR27979.1 - 5.4e-07 29.2 0.1 1.3e-06 27.9 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EGR27979.1 - 4.4e-05 23.1 0.1 0.003 17.1 0.0 2.3 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain IlvN PF07991.12 EGR27979.1 - 4.9e-05 23.0 0.0 0.00023 20.8 0.0 2.0 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3HCDH_N PF02737.18 EGR27979.1 - 0.00056 19.8 0.0 0.0014 18.6 0.0 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 EGR27979.1 - 0.00067 19.3 0.0 0.0015 18.2 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Sacchrp_dh_NADP PF03435.18 EGR27979.1 - 0.0018 18.5 0.0 0.013 15.8 0.0 2.1 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain GFO_IDH_MocA PF01408.22 EGR27979.1 - 0.062 14.1 0.0 0.22 12.4 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold TrkA_N PF02254.18 EGR27979.1 - 0.077 13.3 0.0 0.17 12.1 0.0 1.6 1 1 0 1 1 1 0 TrkA-N domain NAD_binding_4 PF07993.12 EGR27980.1 - 2.1e-67 227.0 0.0 3.9e-67 226.1 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Sterile PF03015.19 EGR27980.1 - 1.7e-15 57.0 2.2 8.2e-15 54.8 2.2 2.3 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.21 EGR27980.1 - 1e-12 47.8 0.0 5.7e-12 45.4 0.1 2.2 2 1 0 2 2 2 1 Acyltransferase Epimerase PF01370.21 EGR27980.1 - 1.7e-07 31.0 0.0 5.8e-07 29.2 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGR27980.1 - 0.0013 18.2 1.1 0.0094 15.4 1.1 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Ephrin PF00812.17 EGR27980.1 - 0.0083 16.1 0.0 0.023 14.7 0.0 1.7 1 0 0 1 1 1 1 Ephrin EF-hand_1 PF00036.32 EGR27981.1 - 3.7e-25 85.5 10.6 6e-08 31.7 0.5 5.3 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 EGR27981.1 - 7.6e-21 74.3 5.1 1.3e-11 44.8 0.2 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGR27981.1 - 6.3e-20 69.7 11.3 3.8e-07 29.3 0.0 4.9 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 EGR27981.1 - 2.2e-17 61.4 7.0 1.4e-05 24.6 0.0 5.4 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 EGR27981.1 - 5.8e-16 58.1 7.9 1.6e-08 34.3 0.8 3.8 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGR27981.1 - 1.9e-08 34.6 3.0 9.1e-05 22.7 0.8 2.5 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Pkinase PF00069.25 EGR27981.1 - 3.4e-06 26.6 0.0 7.5e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain PMBR PF09373.10 EGR27981.1 - 0.00082 19.4 0.4 1.7 8.9 0.0 4.2 5 0 0 5 5 5 1 Pseudomurein-binding repeat EF-hand_11 PF08976.11 EGR27981.1 - 0.098 13.5 0.2 0.56 11.1 0.1 2.0 2 0 0 2 2 2 0 EF-hand domain Guanylate_cyc PF00211.20 EGR27982.1 - 2.1e-77 258.9 5.6 5.7e-41 140.2 0.3 2.6 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain PhoLip_ATPase_C PF16212.5 EGR27982.1 - 1.3e-34 120.1 28.2 1.3e-34 120.1 28.2 6.0 5 2 1 6 6 6 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EGR27982.1 - 0.025 14.9 0.1 5.2 7.3 0.0 2.6 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF3675 PF12428.8 EGR27982.1 - 0.03 14.9 2.4 0.2 12.2 0.2 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3675) DUF2024 PF09630.10 EGR27982.1 - 0.7 9.8 4.2 1.3 9.0 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) Torus PF16131.5 EGR27983.1 - 7e-27 94.3 6.1 7e-27 94.3 6.1 2.0 1 1 1 2 2 2 1 Torus domain U3_snoRNA_assoc PF08297.11 EGR27983.1 - 0.039 14.7 11.9 0.061 14.0 11.9 1.3 1 0 0 1 1 1 0 U3 snoRNA associated zf-CCCH_4 PF18044.1 EGR27983.1 - 0.11 12.4 10.4 0.23 11.3 10.4 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger DDHD PF02862.17 EGR27983.1 - 0.13 12.4 2.1 0.13 12.4 2.1 1.1 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.14 EGR27983.1 - 0.65 8.2 11.2 0.76 8.0 11.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Ferlin_C PF16165.5 EGR27983.1 - 0.77 9.7 7.5 1.2 9.1 7.5 1.2 1 0 0 1 1 1 0 Ferlin C-terminus Presenilin PF01080.17 EGR27983.1 - 0.85 8.3 5.3 0.88 8.3 5.3 1.1 1 0 0 1 1 1 0 Presenilin DUF3043 PF11241.8 EGR27983.1 - 1.2 9.1 5.2 2 8.5 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Peptidase_S49_N PF08496.10 EGR27983.1 - 2.7 8.0 8.6 3.9 7.5 8.6 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal GNAT_acetyltr_2 PF13718.6 EGR27983.1 - 3.1 7.1 6.2 4.3 6.7 6.2 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 RP-C_C PF11800.8 EGR27983.1 - 4.9 7.2 7.7 5.9 6.9 7.7 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region AAA_11 PF13086.6 EGR27983.1 - 5.6 6.7 9.2 7.4 6.3 9.2 1.1 1 0 0 1 1 1 0 AAA domain ALMT PF11744.8 EGR27983.1 - 6 5.6 6.1 6.5 5.5 6.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter FAM176 PF14851.6 EGR27983.1 - 6.4 6.4 9.4 10 5.8 9.4 1.3 1 0 0 1 1 1 0 FAM176 family AIF_C PF14721.6 EGR27983.1 - 7.8 6.9 7.7 14 6.0 7.7 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term LSM PF01423.22 EGR27984.1 - 2.1e-17 62.6 0.0 2.7e-17 62.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EGR27984.1 - 0.17 11.5 0.1 0.35 10.6 0.0 1.5 2 0 0 2 2 2 0 Hfq protein Hydrolase_like PF13242.6 EGR27985.1 - 1.1e-18 67.0 0.0 1.1e-17 63.9 0.0 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like HAD_2 PF13419.6 EGR27985.1 - 2e-09 37.8 0.0 2e-09 37.8 0.0 2.6 2 2 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGR27985.1 - 0.00013 22.3 0.1 0.00019 21.8 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 EGR27985.1 - 0.0014 18.7 0.3 0.026 14.6 0.3 2.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Enkurin PF13864.6 EGR27986.1 - 1e-20 74.0 10.6 1e-20 74.0 10.6 1.7 2 0 0 2 2 2 1 Calmodulin-binding AAA_23 PF13476.6 EGR27986.1 - 0.1 13.1 9.5 0.15 12.5 9.5 1.3 1 0 0 1 1 1 0 AAA domain NuA4 PF09340.10 EGR27986.1 - 0.47 10.4 4.6 0.8 9.6 0.6 2.8 2 1 1 3 3 3 0 Histone acetyltransferase subunit NuA4 PI3_PI4_kinase PF00454.27 EGR27987.1 - 2.1e-27 96.5 2.4 7.3e-26 91.5 2.4 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase zf-AN1 PF01428.16 EGR27988.1 - 1.6e-09 37.8 10.2 1.6e-09 37.8 10.2 3.3 2 1 1 3 3 3 1 AN1-like Zinc finger zf-C2H2_4 PF13894.6 EGR27988.1 - 0.00059 20.5 13.8 0.029 15.2 0.1 4.1 4 0 0 4 4 4 1 C2H2-type zinc finger zf-C2H2 PF00096.26 EGR27988.1 - 0.0099 16.3 0.1 0.0099 16.3 0.1 4.3 4 0 0 4 4 4 2 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 EGR27988.1 - 0.13 12.3 0.1 0.13 12.3 0.1 3.8 4 0 0 4 4 4 0 C2H2-type zinc finger SHS2_FTSA PF02491.20 EGR27988.1 - 0.16 12.4 0.1 0.35 11.3 0.0 1.6 2 0 0 2 2 2 0 SHS2 domain inserted in FTSA zf-Di19 PF05605.12 EGR27988.1 - 1.3 9.3 0.1 1.3 9.3 0.1 3.6 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Oxysterol_BP PF01237.18 EGR27990.1 - 1.5e-18 66.8 28.8 8.4e-16 57.8 0.0 4.5 3 1 2 5 5 5 3 Oxysterol-binding protein zf-rbx1 PF12678.7 EGR27990.1 - 0.0078 16.5 3.4 0.044 14.1 3.4 2.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGR27990.1 - 0.0096 16.2 6.9 0.0096 16.2 6.9 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EGR27990.1 - 0.024 14.7 5.7 0.067 13.2 5.7 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-TFIIIC PF12660.7 EGR27990.1 - 0.038 13.9 4.3 0.18 11.8 4.3 2.3 1 1 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex zf-C3HC4_2 PF13923.6 EGR27990.1 - 0.089 12.7 8.5 0.25 11.2 8.5 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) CcmH PF03918.14 EGR27990.1 - 0.089 12.1 0.1 0.089 12.1 0.1 2.2 2 0 0 2 2 1 0 Cytochrome C biogenesis protein Strep_his_triad PF04270.13 EGR27990.1 - 0.14 12.2 0.4 0.47 10.5 0.0 2.2 2 0 0 2 2 2 0 Streptococcal histidine triad protein Zn_ribbon_17 PF17120.5 EGR27990.1 - 0.16 11.6 5.5 0.36 10.5 5.5 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type MutS_III PF05192.18 EGR27990.1 - 0.19 11.9 2.4 0.32 11.2 1.5 1.9 2 0 0 2 2 2 0 MutS domain III Zf_RING PF16744.5 EGR27990.1 - 0.25 11.5 3.5 0.99 9.6 3.5 2.1 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING_11 PF17123.5 EGR27990.1 - 0.4 10.5 4.8 1.2 8.9 4.8 1.9 1 0 0 1 1 1 0 RING-like zinc finger zf-RanBP PF00641.18 EGR27990.1 - 0.85 9.0 6.9 0.65 9.4 0.6 2.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others zf-RING_5 PF14634.6 EGR27990.1 - 1.1 9.3 11.5 0.11 12.5 6.5 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4 PF00097.25 EGR27990.1 - 2.2 8.2 12.3 0.36 10.7 7.4 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) His_Phos_2 PF00328.22 EGR27991.1 - 1.6e-20 73.8 0.4 1.6e-20 73.8 0.4 1.8 1 1 1 2 2 2 1 Histidine phosphatase superfamily (branch 2) DUF494 PF04361.13 EGR27991.1 - 0.064 13.1 0.4 0.32 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF494) POT1 PF02765.17 EGR27991.1 - 0.065 13.1 1.2 0.14 12.0 0.3 1.9 2 0 0 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 PBECR1 PF18809.1 EGR27991.1 - 0.25 12.0 1.9 0.32 11.7 0.6 1.9 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 Ras PF00071.22 EGR27992.1 - 1.9e-39 134.9 0.4 2.2e-39 134.7 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR27992.1 - 2.3e-24 85.9 0.1 3.1e-24 85.5 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR27992.1 - 3.2e-13 49.5 0.1 4.2e-13 49.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR27992.1 - 2.6e-05 24.3 0.0 3.4e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGR27992.1 - 4.4e-05 23.4 0.1 0.019 14.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EGR27992.1 - 0.00012 21.5 0.7 0.00014 21.3 0.7 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Alg6_Alg8 PF03155.15 EGR27993.1 - 3.7e-91 306.5 23.9 4.9e-91 306.1 23.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family GT87 PF09594.10 EGR27993.1 - 0.013 15.3 3.2 0.03 14.1 2.9 1.6 1 1 0 1 1 1 0 Glycosyltransferase family 87 DUF1418 PF07214.12 EGR27993.1 - 0.059 13.2 0.3 34 4.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1418) EF-hand_7 PF13499.6 EGR27994.1 - 3.8e-11 43.3 0.7 3.8e-10 40.1 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGR27994.1 - 2.5e-10 39.2 4.2 3.9e-06 26.0 0.8 2.9 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGR27994.1 - 2e-08 33.5 4.5 4.9e-05 22.9 0.5 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGR27994.1 - 3.5e-08 32.6 4.5 8e-05 21.9 1.3 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGR27994.1 - 7.6e-08 32.1 0.0 2.5e-07 30.4 0.0 1.9 1 0 0 1 1 1 1 EF-hand domain pair EnY2 PF10163.9 EGR27994.1 - 0.4 11.1 0.1 0.4 11.1 0.1 2.8 4 0 0 4 4 4 0 Transcription factor e(y)2 SPARC_Ca_bdg PF10591.9 EGR27994.1 - 1.2 9.5 5.6 1.9 8.8 0.1 3.3 2 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Tubulin PF00091.25 EGR27996.1 - 8.7e-69 231.7 0.0 1.6e-68 230.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGR27996.1 - 6.8e-42 142.6 0.1 1e-41 142.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGR27996.1 - 0.00022 21.5 0.0 0.00054 20.2 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EGR27996.1 - 0.0083 15.3 0.1 0.019 14.1 0.0 1.6 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 EGR27996.1 - 0.0091 15.7 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Aa_trans PF01490.18 EGR27997.1 - 1.4e-58 198.5 39.0 1.7e-58 198.3 39.0 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EGR27997.1 - 1.1e-05 24.7 18.6 1.1e-05 24.7 18.6 2.3 1 1 0 2 2 2 1 Tryptophan/tyrosine permease family DUF4183 PF13799.6 EGR27997.1 - 0.042 13.7 0.1 0.14 12.0 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4183) RNA_pol_Rpb1_5 PF04998.17 EGR27999.1 - 1.5e-94 316.4 2.0 2.5e-94 315.7 1.3 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_6 PF04992.14 EGR27999.1 - 2.7e-44 151.3 11.5 3.5e-44 150.9 10.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_4 PF05000.17 EGR27999.1 - 3e-25 88.3 0.3 1.2e-24 86.3 0.3 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_3 PF04983.18 EGR27999.1 - 4.6e-24 85.1 1.6 1.4e-23 83.6 0.0 2.7 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 3 Imm5 PF14423.6 EGR28000.1 - 0.36 11.0 5.6 0.51 10.6 0.3 2.7 3 0 0 3 3 3 0 Immunity protein Imm5 EF-hand_7 PF13499.6 EGR28001.1 - 2e-19 69.8 3.8 5.2e-10 39.6 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR28001.1 - 1.4e-14 52.5 3.3 0.037 13.6 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGR28001.1 - 4.9e-13 47.9 3.0 0.0067 16.3 0.2 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EGR28001.1 - 2.2e-08 33.2 0.3 0.011 15.2 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_10 PF14788.6 EGR28001.1 - 0.00013 21.8 0.5 0.12 12.3 0.1 3.0 2 1 1 3 3 3 2 EF hand EF-hand_8 PF13833.6 EGR28001.1 - 0.00053 19.8 0.6 5.6 6.9 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain pair Caleosin PF05042.13 EGR28001.1 - 0.0011 18.9 0.7 0.33 10.9 0.1 2.5 2 1 0 2 2 2 2 Caleosin related protein Dockerin_1 PF00404.18 EGR28001.1 - 0.0017 18.5 1.2 0.13 12.4 0.1 2.7 2 1 1 3 3 3 1 Dockerin type I domain DUF5088 PF17008.5 EGR28001.1 - 0.023 14.4 1.2 0.034 13.9 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5088) MFS_1 PF07690.16 EGR28002.1 - 3.5e-07 29.5 24.2 5.9e-06 25.4 11.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TPR_2 PF07719.17 EGR28005.1 - 1.9e-42 140.0 41.5 8.1e-09 34.9 1.2 12.5 11 2 1 12 12 12 8 Tetratricopeptide repeat TPR_1 PF00515.28 EGR28005.1 - 5.2e-38 127.3 49.0 6.3e-11 41.6 1.5 13.0 13 0 0 13 13 13 8 Tetratricopeptide repeat TPR_8 PF13181.6 EGR28005.1 - 3.9e-32 107.8 48.7 5.3e-08 32.5 0.8 13.1 12 1 3 15 15 13 8 Tetratricopeptide repeat TPR_12 PF13424.6 EGR28005.1 - 4.2e-29 100.6 22.4 1.2e-08 35.1 2.6 7.9 7 2 1 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 EGR28005.1 - 3.2e-25 88.5 5.7 2.2e-05 25.0 0.0 8.3 4 2 6 10 10 10 7 Tetratricopeptide repeat Oxysterol_BP PF01237.18 EGR28005.1 - 7.6e-25 87.5 0.5 7.6e-25 87.5 0.5 1.9 2 0 0 2 2 2 1 Oxysterol-binding protein TPR_7 PF13176.6 EGR28005.1 - 1.7e-21 74.6 27.1 2.1e-06 27.3 0.0 11.4 14 0 0 14 14 11 5 Tetratricopeptide repeat TPR_19 PF14559.6 EGR28005.1 - 4.1e-21 75.3 29.7 1.1e-05 25.9 1.2 8.5 5 2 4 9 9 9 7 Tetratricopeptide repeat TPR_14 PF13428.6 EGR28005.1 - 1.3e-20 72.3 7.2 0.34 11.8 0.0 9.9 6 3 3 10 10 9 5 Tetratricopeptide repeat TPR_6 PF13174.6 EGR28005.1 - 7.7e-16 57.6 24.9 0.0012 19.4 0.1 11.4 11 0 0 11 11 11 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGR28005.1 - 7.9e-16 57.5 35.1 6e-08 32.3 0.0 10.4 6 2 4 10 10 10 3 TPR repeat TPR_10 PF13374.6 EGR28005.1 - 1.7e-14 53.1 15.0 0.014 15.3 0.2 10.3 10 0 0 10 10 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR28005.1 - 2.5e-12 46.8 31.0 0.0016 18.6 1.3 6.8 2 2 4 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EGR28005.1 - 1.8e-10 40.4 34.1 0.0028 17.9 0.1 10.0 10 0 0 10 10 9 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EGR28005.1 - 3.7e-08 33.1 0.3 0.0019 17.6 0.0 3.9 1 1 3 4 4 4 2 MalT-like TPR region TPR_9 PF13371.6 EGR28005.1 - 9.1e-07 28.9 4.2 5.2 7.3 0.1 5.7 5 1 2 7 7 6 2 Tetratricopeptide repeat TPR_21 PF09976.9 EGR28005.1 - 2.1e-05 24.3 29.8 0.011 15.4 0.5 6.5 1 1 3 6 6 6 3 Tetratricopeptide repeat-like domain PPR PF01535.20 EGR28005.1 - 6.8e-05 22.8 2.8 3.5 8.1 0.0 5.8 5 0 0 5 5 5 1 PPR repeat TPR_15 PF13429.6 EGR28005.1 - 0.00018 20.8 24.2 0.0012 18.2 12.4 3.7 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_20 PF14561.6 EGR28005.1 - 0.0017 18.6 20.9 0.0069 16.7 0.1 6.8 5 2 0 6 6 6 1 Tetratricopeptide repeat RPN7 PF10602.9 EGR28005.1 - 0.0098 15.6 21.6 0.22 11.2 0.5 5.3 2 1 1 5 5 5 2 26S proteasome subunit RPN7 Rapsyn_N PF10579.9 EGR28005.1 - 0.019 15.1 0.1 0.019 15.1 0.1 4.7 6 0 0 6 6 5 0 Rapsyn N-terminal myristoylation and linker region TPR_5 PF12688.7 EGR28005.1 - 0.027 14.7 1.6 5.1 7.4 0.0 4.5 3 2 3 6 6 6 0 Tetratrico peptide repeat OAM_alpha PF16552.5 EGR28005.1 - 0.068 13.1 0.0 0.25 11.2 0.0 2.0 1 0 0 1 1 1 0 D-ornithine 4,5-aminomutase alpha-subunit SLT_L PF14718.6 EGR28005.1 - 0.15 12.3 1.5 0.47 10.6 0.1 2.7 3 0 0 3 3 1 0 Soluble lytic murein transglycosylase L domain SHNi-TPR PF10516.9 EGR28005.1 - 0.61 9.6 5.4 0.67 9.5 0.4 3.7 4 0 0 4 4 4 0 SHNi-TPR Sel1 PF08238.12 EGR28005.1 - 3.2 8.6 7.8 13 6.6 0.1 4.9 4 0 0 4 4 4 0 Sel1 repeat Pkinase PF00069.25 EGR28006.1 - 2.4e-65 220.6 0.0 6.7e-65 219.1 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28006.1 - 2.8e-36 125.1 0.0 6.5e-36 123.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 EGR28006.1 - 1e-16 61.2 7.9 1.1e-12 48.4 2.8 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGR28006.1 - 2.8e-13 50.1 2.6 1.8e-05 25.2 0.2 3.3 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGR28006.1 - 8e-13 48.3 1.0 8.1e-05 22.8 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGR28006.1 - 1.9e-11 43.9 7.6 0.00047 20.5 0.1 4.0 3 1 1 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EGR28006.1 - 1.8e-09 37.1 1.5 0.038 14.5 0.0 4.0 3 0 0 3 3 3 2 Ankyrin repeat APH PF01636.23 EGR28006.1 - 0.2 11.6 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family IBR PF01485.21 EGR28008.1 - 1.2e-15 57.4 26.3 1.4e-09 38.0 10.3 4.1 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EGR28008.1 - 0.00011 22.4 8.9 0.00011 22.4 8.9 3.9 2 1 1 3 3 3 1 Ring finger domain PP2C PF00481.21 EGR28009.1 - 1.2e-39 136.5 0.0 1.7e-39 136.0 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGR28009.1 - 1.4e-05 24.8 0.0 3e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Kinase-like PF14531.6 EGR28009.1 - 0.039 13.3 1.2 0.073 12.4 0.6 1.7 1 1 0 1 1 1 0 Kinase-like Thg1C PF14413.6 EGR28010.1 - 1.7 8.9 22.7 7.6 6.7 22.3 1.9 1 1 0 1 1 1 0 Thg1 C terminal domain LisH_2 PF16045.5 EGR28012.1 - 1.6e-10 39.8 0.8 1.6e-10 39.8 0.8 2.1 2 0 0 2 2 2 1 LisH FOP_dimer PF09398.10 EGR28012.1 - 3.9e-06 27.0 1.0 3.9e-06 27.0 1.0 3.9 4 0 0 4 4 4 1 FOP N terminal dimerisation domain Pkinase PF00069.25 EGR28014.1 - 8.3e-56 189.3 5.9 8.3e-56 189.3 5.9 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28014.1 - 8.4e-42 143.2 1.1 1.2e-41 142.7 1.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR28014.1 - 3.8e-07 29.2 0.2 7.4e-07 28.3 0.2 1.5 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGR28014.1 - 3.7e-06 26.5 0.3 3.7e-06 26.5 0.3 2.4 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGR28014.1 - 0.031 13.7 0.3 0.054 12.8 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kdo_hydroxy PF11004.8 EGR28014.1 - 0.037 13.3 1.0 0.17 11.1 0.8 2.0 2 0 0 2 2 2 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase DUF2777 PF10949.8 EGR28015.1 - 0.014 15.1 0.2 0.052 13.2 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2777) DSPc PF00782.20 EGR28016.1 - 1.9e-29 102.2 1.9 3.4e-29 101.3 1.9 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGR28016.1 - 4.8e-05 23.0 0.3 7.5e-05 22.4 0.3 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGR28016.1 - 0.0048 17.0 0.0 0.0078 16.3 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 EGR28016.1 - 0.023 14.4 0.3 0.023 14.4 0.3 1.7 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Init_tRNA_PT PF04179.12 EGR28016.1 - 0.037 14.3 0.7 0.081 13.2 0.1 1.9 2 0 0 2 2 2 0 Rit1 DUSP-like domain NPL4 PF05021.15 EGR28019.1 - 4.4e-35 121.5 6.0 1.1e-33 116.9 6.0 2.2 1 1 0 1 1 1 1 NPL4 family zf-NPL4 PF05020.15 EGR28019.1 - 2.7e-19 69.8 8.3 2.7e-19 69.8 8.3 2.9 2 1 1 3 3 3 1 NPL4 family, putative zinc binding region UN_NPL4 PF11543.8 EGR28019.1 - 3.4e-07 30.7 2.3 6.8e-07 29.7 0.1 2.6 3 0 0 3 3 3 1 Nuclear pore localisation protein NPL4 ubiquitin PF00240.23 EGR28019.1 - 0.003 17.3 0.1 0.0093 15.7 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin family JAB PF01398.21 EGR28019.1 - 0.063 13.2 0.1 0.25 11.3 0.1 2.0 1 0 0 1 1 1 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ubiquitin_2 PF14560.6 EGR28019.1 - 0.084 13.3 0.1 0.21 12.1 0.1 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain FpoO PF10621.9 EGR28019.1 - 0.45 10.9 9.7 0.15 12.4 4.2 2.3 1 1 1 2 2 2 0 F420H2 dehydrogenase subunit FpoO zf-RING_9 PF13901.6 EGR28020.1 - 0.77 9.7 7.4 0.081 12.9 1.6 2.3 2 1 0 2 2 2 0 Putative zinc-RING and/or ribbon AAA_6 PF12774.7 EGR28021.1 - 2.9e-123 411.0 0.1 3.5e-123 410.8 0.1 1.1 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA_5 PF07728.14 EGR28021.1 - 2.4e-13 50.3 0.0 8.4e-05 22.6 0.0 3.5 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGR28021.1 - 2e-07 31.5 0.0 0.015 15.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 EGR28021.1 - 5.5e-06 27.0 0.0 0.081 13.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EGR28021.1 - 7.5e-06 26.4 0.0 0.03 14.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGR28021.1 - 1.2e-05 25.6 0.2 0.19 12.0 0.0 3.0 3 0 0 3 3 3 2 AAA domain Rad17 PF03215.15 EGR28021.1 - 3.2e-05 23.9 0.8 0.14 12.1 0.1 2.4 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_30 PF13604.6 EGR28021.1 - 9.2e-05 22.2 0.1 0.23 11.1 0.0 2.2 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGR28021.1 - 0.00019 21.8 0.1 0.22 12.0 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_7 PF12775.7 EGR28021.1 - 0.00033 20.2 0.2 0.46 10.0 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_19 PF13245.6 EGR28021.1 - 0.00061 20.1 0.2 0.72 10.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EGR28021.1 - 0.00074 19.7 0.0 0.28 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EGR28021.1 - 0.0015 18.0 0.0 0.038 13.4 0.0 2.5 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 EGR28021.1 - 0.0029 16.7 0.4 0.073 12.1 0.1 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_24 PF13479.6 EGR28021.1 - 0.0036 17.1 0.0 2.8 7.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain ATP_bind_1 PF03029.17 EGR28021.1 - 0.0045 16.8 0.6 0.58 9.9 0.0 2.6 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_28 PF13521.6 EGR28021.1 - 0.0061 16.8 0.0 2.6 8.3 0.0 2.6 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 EGR28021.1 - 0.011 15.7 0.2 6.9 6.6 0.1 2.6 2 0 0 2 2 2 0 NACHT domain DUF853 PF05872.12 EGR28021.1 - 0.021 13.4 0.2 2.7 6.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) TsaE PF02367.17 EGR28021.1 - 0.047 13.7 0.0 5.7 7.0 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KTI12 PF08433.10 EGR28021.1 - 0.049 13.1 0.4 0.39 10.1 0.0 2.4 3 0 0 3 3 3 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 EGR28021.1 - 0.063 12.5 0.1 10 5.4 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin IstB_IS21 PF01695.17 EGR28021.1 - 0.1 12.4 0.1 1.6 8.5 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein PRK PF00485.18 EGR28021.1 - 0.13 12.0 0.8 2 8.1 0.0 2.6 3 0 0 3 3 3 0 Phosphoribulokinase / Uridine kinase family SRP54 PF00448.22 EGR28021.1 - 0.17 11.5 1.4 15 5.2 0.1 2.7 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain AAA_11 PF13086.6 EGR28021.1 - 0.28 10.9 1.1 6.1 6.5 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_9 PF12781.7 EGR28022.1 - 9.3e-66 221.1 6.7 9.3e-66 221.1 6.7 4.1 4 1 0 4 4 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 EGR28022.1 - 1.2e-54 185.4 9.5 1.2e-39 136.2 0.4 3.8 2 1 1 3 3 3 2 P-loop containing dynein motor region D4 Dynein_heavy PF03028.15 EGR28022.1 - 1.8e-47 160.3 2.0 2.1e-42 144.0 0.4 3.6 3 0 0 3 3 3 2 Dynein heavy chain region D6 P-loop domain AAA_lid_11 PF18198.1 EGR28022.1 - 3.5e-38 131.0 2.5 3.9e-37 127.6 1.2 2.9 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 EGR28022.1 - 2.2e-25 89.4 24.2 2.5e-24 86.0 24.2 2.5 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 EGR28022.1 - 8.5e-05 21.9 1.2 8.5e-05 21.9 1.2 4.1 4 1 0 4 4 4 1 Dynein heavy chain C-terminal domain Sugar_tr PF00083.24 EGR28024.1 - 1.2e-72 245.3 26.2 1.4e-72 245.1 26.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGR28024.1 - 1.7e-22 79.8 16.5 1.7e-22 79.8 16.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF3792 PF12670.7 EGR28024.1 - 0.012 15.7 9.6 0.012 15.7 9.6 4.4 3 2 2 5 5 5 0 Protein of unknown function (DUF3792) Tli4_N PF18443.1 EGR28024.1 - 0.014 15.8 0.1 0.027 14.8 0.1 1.4 1 0 0 1 1 1 0 Tle cognate immunity protein 4 N-terminal domain APG6 PF04111.12 EGR28025.1 - 5.6e-35 120.9 4.0 5.6e-35 120.9 4.0 2.1 2 1 0 2 2 2 1 Apg6 BARA domain APG6_N PF17675.1 EGR28025.1 - 0.002 18.7 30.3 0.002 18.7 30.3 2.4 1 1 1 2 2 2 1 Apg6 coiled-coil region Cob_adeno_trans PF01923.18 EGR28025.1 - 0.0082 16.3 4.4 0.022 14.9 4.4 1.7 1 0 0 1 1 1 1 Cobalamin adenosyltransferase Uds1 PF15456.6 EGR28025.1 - 0.012 15.7 6.4 0.03 14.5 6.4 1.7 1 0 0 1 1 1 0 Up-regulated During Septation zinc-ribbons_6 PF07191.12 EGR28025.1 - 0.2 11.6 3.8 0.64 10.0 3.8 1.9 1 0 0 1 1 1 0 zinc-ribbons Cytochrom_c3_2 PF14537.6 EGR28025.1 - 0.22 12.0 3.5 0.45 11.0 3.1 1.8 1 1 0 1 1 1 0 Cytochrome c3 DUF4140 PF13600.6 EGR28025.1 - 0.29 11.6 10.8 4.9 7.6 5.1 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Laminin_II PF06009.12 EGR28025.1 - 0.41 10.6 13.8 0.15 12.1 10.2 1.9 1 1 1 2 2 2 0 Laminin Domain II Exonuc_VII_L PF02601.15 EGR28025.1 - 0.91 9.0 12.3 1.3 8.5 12.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit C1_2 PF03107.16 EGR28025.1 - 3.1 8.2 6.5 1.1 9.6 3.2 2.0 2 0 0 2 2 1 0 C1 domain FapA PF03961.13 EGR28025.1 - 3.4 6.2 24.2 4.1 5.9 23.1 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF1664 PF07889.12 EGR28025.1 - 6 6.9 15.6 6.5 6.8 3.6 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Spc24 PF08286.11 EGR28025.1 - 8.3 6.7 26.8 32 4.8 17.2 3.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Bromodomain PF00439.25 EGR28026.1 - 1.8e-19 69.6 2.1 5e-19 68.2 2.1 1.8 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 EGR28026.1 - 2.8e-18 65.8 0.4 2.8e-18 65.8 0.4 2.8 3 0 0 3 3 3 1 Bromodomain extra-terminal - transcription regulation DUF5409 PF17421.2 EGR28026.1 - 0.044 14.5 3.1 0.11 13.2 3.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5409) DUF948 PF06103.11 EGR28026.1 - 0.28 11.4 1.8 0.32 11.3 0.2 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) MFS_2 PF13347.6 EGR28027.1 - 0.092 11.3 1.4 0.1 11.1 0.5 1.4 1 1 0 1 1 1 0 MFS/sugar transport protein FtsX_ECD PF18075.1 EGR28027.1 - 0.14 12.8 8.3 0.052 14.2 4.1 2.0 2 0 0 2 2 2 0 FtsX extracellular domain HigB-like_toxin PF05015.13 EGR28027.1 - 1.3 9.5 13.1 0.19 12.2 1.6 2.8 1 1 1 3 3 3 0 RelE-like toxin of type II toxin-antitoxin system HigB MBOAT PF03062.19 EGR28028.1 - 2.3e-26 93.0 25.2 3.5e-26 92.4 24.8 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Peptidase_M14 PF00246.24 EGR28029.1 - 1.2e-28 100.8 4.9 1.6e-23 84.0 3.2 2.4 1 1 1 2 2 2 2 Zinc carboxypeptidase zf-C2H2_4 PF13894.6 EGR28029.1 - 0.12 13.3 0.3 0.56 11.2 0.3 2.2 1 0 0 1 1 1 0 C2H2-type zinc finger AAA_6 PF12774.7 EGR28030.1 - 7.5e-142 472.1 4.3 1.2e-141 471.5 0.0 3.4 3 0 0 3 3 2 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGR28030.1 - 2.3e-101 339.8 21.5 2.3e-101 339.8 21.5 4.1 3 1 0 3 3 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EGR28030.1 - 6e-90 301.1 0.0 2.6e-89 299.0 0.0 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EGR28030.1 - 1e-80 271.2 0.3 5.2e-80 268.9 0.0 2.4 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 EGR28030.1 - 2.9e-77 258.7 4.5 2.9e-77 258.7 4.5 3.6 3 0 0 3 3 1 1 ATP-binding dynein motor region MT PF12777.7 EGR28030.1 - 1.4e-76 257.8 18.1 3.8e-76 256.3 18.1 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_7 PF12775.7 EGR28030.1 - 1.7e-58 197.1 2.1 9.3e-54 181.7 0.0 4.2 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGR28030.1 - 3.5e-51 173.3 1.4 9.1e-51 171.9 0.1 2.5 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGR28030.1 - 5.8e-32 110.3 0.5 1.5e-30 105.7 0.0 3.3 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 EGR28030.1 - 9.4e-24 83.5 0.3 4.3e-23 81.4 0.3 2.2 1 0 0 1 1 1 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 EGR28030.1 - 1.6e-22 80.0 0.2 1.2e-21 77.2 0.2 2.8 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Kelch_4 PF13418.6 EGR28030.1 - 2e-20 72.5 7.6 2.9e-06 27.2 0.0 7.2 7 0 0 7 7 6 2 Galactose oxidase, central domain Kelch_3 PF13415.6 EGR28030.1 - 1.1e-18 67.1 9.2 0.0014 18.9 0.0 8.2 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EGR28030.1 - 2.4e-18 65.7 8.3 0.00011 22.2 0.1 6.9 6 0 0 6 6 6 4 Kelch motif AAA_5 PF07728.14 EGR28030.1 - 1.2e-17 64.2 0.0 6.3e-05 23.0 0.0 5.3 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) Kelch_1 PF01344.25 EGR28030.1 - 8.4e-17 60.5 0.3 2.7e-05 23.7 0.0 5.2 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 EGR28030.1 - 3.9e-15 55.1 10.1 5.7e-05 22.9 0.0 7.3 8 0 0 8 8 6 3 Kelch motif Kelch_6 PF13964.6 EGR28030.1 - 7.3e-13 48.3 8.8 0.00017 21.7 0.0 6.3 5 1 1 6 6 6 3 Kelch motif AAA PF00004.29 EGR28030.1 - 5.2e-08 33.4 3.1 0.08 13.4 0.0 5.3 5 0 0 5 5 5 2 ATPase family associated with various cellular activities (AAA) TIG PF01833.24 EGR28030.1 - 7.8e-08 32.3 0.9 2.2e-07 30.8 0.9 1.8 1 0 0 1 1 1 1 IPT/TIG domain AAA_22 PF13401.6 EGR28030.1 - 4.3e-07 30.3 1.5 0.48 10.7 0.0 4.4 5 0 0 5 5 3 2 AAA domain AAA_16 PF13191.6 EGR28030.1 - 2.7e-05 24.6 5.2 0.44 10.9 0.0 5.5 5 0 0 5 5 5 1 AAA ATPase domain RNA_helicase PF00910.22 EGR28030.1 - 4e-05 24.0 0.4 1.9 8.9 0.0 4.2 3 0 0 3 3 3 2 RNA helicase Filamin PF00630.19 EGR28030.1 - 8.6e-05 23.3 0.1 0.00026 21.7 0.1 1.9 1 0 0 1 1 1 1 Filamin/ABP280 repeat NACHT PF05729.12 EGR28030.1 - 0.00042 20.3 0.1 0.021 14.7 0.0 3.2 3 0 0 3 3 3 1 NACHT domain AAA_33 PF13671.6 EGR28030.1 - 0.004 17.3 1.3 5.5 7.1 0.0 4.6 5 0 0 5 5 3 0 AAA domain AAA_18 PF13238.6 EGR28030.1 - 0.0045 17.5 9.2 1.3 9.6 0.0 5.1 6 0 0 6 6 3 2 AAA domain Sigma54_activat PF00158.26 EGR28030.1 - 0.02 14.6 0.1 1.8 8.2 0.0 3.1 4 0 0 4 4 2 0 Sigma-54 interaction domain LPP PF04728.13 EGR28030.1 - 0.023 15.1 9.2 0.013 15.9 5.3 2.8 2 0 0 2 2 1 0 Lipoprotein leucine-zipper TsaE PF02367.17 EGR28030.1 - 0.026 14.5 0.4 2.3 8.2 0.0 3.7 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CDC45 PF02724.14 EGR28030.1 - 0.06 11.6 20.5 0.41 8.9 1.9 3.2 3 0 0 3 3 3 0 CDC45-like protein Mg_chelatase PF01078.21 EGR28030.1 - 0.069 12.5 0.2 9.4 5.5 0.0 3.8 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EGR28030.1 - 0.11 12.8 1.6 9.8 6.5 0.0 3.4 4 0 0 4 4 2 0 AAA domain ABC_tran PF00005.27 EGR28030.1 - 0.15 12.6 8.5 5.6 7.5 0.0 5.2 5 0 0 5 5 3 0 ABC transporter CbiA PF01656.23 EGR28030.1 - 0.24 11.4 0.6 55 3.8 0.0 4.0 3 0 0 3 3 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain RsgA_GTPase PF03193.16 EGR28030.1 - 4.4 7.2 6.2 2.6 7.9 0.0 3.8 3 0 0 3 3 2 0 RsgA GTPase Pkinase PF00069.25 EGR28031.1 - 1.4e-27 96.7 0.1 1.9e-27 96.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28031.1 - 2.6e-15 56.4 0.0 3.5e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR28031.1 - 3.7e-08 32.5 0.1 5.1e-08 32.1 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR28031.1 - 0.034 13.5 0.1 0.053 12.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5402 PF17393.2 EGR28031.1 - 0.08 12.9 0.0 0.31 11.0 0.0 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5402) APH PF01636.23 EGR28031.1 - 0.11 12.4 0.0 2.7 7.8 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Antimicrobial14 PF08109.11 EGR28031.1 - 0.15 12.1 1.2 0.4 10.8 0.0 2.2 2 0 0 2 2 2 0 Lactocin 705 family Pkinase PF00069.25 EGR28032.1 - 8.8e-19 67.9 2.1 1.7e-18 66.9 2.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28032.1 - 6.8e-13 48.5 0.9 1.3e-12 47.6 0.9 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28032.1 - 0.00065 19.1 0.1 0.0012 18.3 0.1 1.5 1 0 0 1 1 1 1 Kinase-like Ank_4 PF13637.6 EGR28033.1 - 1.3e-10 41.6 0.0 7.3e-06 26.4 0.0 3.9 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGR28033.1 - 1.9e-09 38.0 0.1 4.7e-08 33.5 0.0 2.4 1 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGR28033.1 - 3.2e-09 36.8 0.0 5.3e-07 29.8 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR28033.1 - 2.6e-08 33.5 0.1 0.00035 20.8 0.0 4.0 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EGR28033.1 - 7.5e-06 26.2 0.0 0.0017 18.7 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeat MCR_C PF04609.12 EGR28033.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.1 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C Exo_endo_phos PF03372.23 EGR28034.1 - 7.6e-05 22.3 0.0 9.7e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EGR28034.1 - 0.015 15.2 0.0 0.028 14.2 0.0 1.6 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase Metallophos PF00149.28 EGR28035.1 - 1.2e-08 35.7 0.0 0.00021 21.8 0.0 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Kinesin PF00225.23 EGR28036.1 - 3.1e-107 358.4 9.8 3.1e-107 358.4 9.8 3.2 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EGR28036.1 - 1.2e-21 77.3 3.4 1.2e-21 77.3 3.4 4.5 4 2 1 5 5 5 1 Microtubule binding AAA_22 PF13401.6 EGR28036.1 - 2.9 8.2 0.0 2.9 8.2 0.0 4.1 4 0 0 4 4 4 0 AAA domain Clathrin PF00637.20 EGR28037.1 - 7.9e-11 42.0 8.1 7.9e-11 42.0 8.1 4.6 3 1 0 3 3 3 2 Region in Clathrin and VPS VPS11_C PF12451.8 EGR28037.1 - 5.6e-05 23.3 0.4 5.6e-05 23.3 0.4 3.0 2 1 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 EGR28037.1 - 0.0017 18.4 8.6 0.0035 17.3 8.6 1.6 1 0 0 1 1 1 1 Zinc-finger zf-RING_5 PF14634.6 EGR28037.1 - 0.055 13.4 8.7 0.17 11.8 8.7 1.9 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGR28037.1 - 0.14 12.3 5.6 0.4 10.7 5.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGR28037.1 - 7.5 6.5 17.1 0.069 13.0 8.6 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PhoLip_ATPase_C PF16212.5 EGR28039.1 - 2.6e-54 184.6 35.6 2.6e-54 184.6 35.6 2.9 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGR28039.1 - 5.9e-18 64.3 7.6 5.9e-18 64.3 7.6 2.8 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGR28039.1 - 2.1e-11 43.7 0.3 5.6e-10 39.2 0.0 2.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGR28039.1 - 5.9e-07 30.0 5.6 0.0069 16.7 3.4 3.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGR28039.1 - 3.2e-05 23.5 0.1 0.00027 20.5 0.0 2.5 2 1 0 2 2 2 1 E1-E2 ATPase Spore_GerAC PF05504.11 EGR28039.1 - 0.0053 17.0 5.1 0.019 15.2 5.1 2.0 1 0 0 1 1 1 1 Spore germination B3/ GerAC like, C-terminal IF-2B PF01008.17 EGR28039.1 - 0.018 14.2 1.3 0.042 13.1 1.3 1.6 1 0 0 1 1 1 0 Initiation factor 2 subunit family NYN_YacP PF05991.11 EGR28039.1 - 0.068 13.1 0.8 0.17 11.8 0.8 1.6 1 0 0 1 1 1 0 YacP-like NYN domain Robl_LC7 PF03259.17 EGR28040.1 - 9e-20 70.3 0.0 1e-19 70.1 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 EGR28040.1 - 0.0039 17.1 0.1 0.0053 16.7 0.1 1.2 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Helveticin_J PF17312.2 EGR28040.1 - 0.016 14.4 0.6 0.017 14.2 0.6 1.0 1 0 0 1 1 1 0 Bacteriocin helveticin-J CHASE8 PF17152.4 EGR28040.1 - 0.066 13.5 0.0 0.18 12.1 0.0 1.7 1 1 0 1 1 1 0 Periplasmic sensor domain S4 PF01479.25 EGR28041.1 - 2.1e-10 40.2 2.2 2.6e-10 39.9 0.4 2.1 3 0 0 3 3 3 1 S4 domain Na_H_Exchanger PF00999.21 EGR28042.1 - 2e-39 135.5 39.9 2.7e-39 135.0 39.9 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TPR_11 PF13414.6 EGR28043.1 - 8.2e-23 79.8 13.7 8.8e-09 34.9 0.1 6.6 4 1 2 6 6 6 5 TPR repeat TPR_2 PF07719.17 EGR28043.1 - 1e-20 72.1 16.6 8.7e-07 28.6 1.0 6.4 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGR28043.1 - 1.4e-20 72.2 14.6 3.8e-08 32.8 0.6 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGR28043.1 - 2e-17 62.2 16.2 2.6e-05 24.3 0.1 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGR28043.1 - 2e-14 52.5 2.6 1.4e-05 24.9 0.3 5.2 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGR28043.1 - 1.2e-13 50.6 10.6 3.8e-06 27.3 0.3 6.8 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGR28043.1 - 3.6e-12 46.6 7.4 0.00014 22.3 0.1 5.3 2 1 0 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGR28043.1 - 4.3e-12 46.5 4.7 1.4e-07 32.0 2.8 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGR28043.1 - 8.1e-11 41.2 0.5 0.03 14.4 0.0 4.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGR28043.1 - 7.1e-10 39.0 11.1 2.1e-08 34.4 0.9 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGR28043.1 - 2.2e-06 27.7 0.4 0.0026 17.9 0.0 3.7 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGR28043.1 - 5.3e-05 23.0 6.9 0.032 14.1 0.7 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_20 PF14561.6 EGR28043.1 - 0.0052 17.1 0.1 0.0052 17.1 0.1 5.0 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGR28043.1 - 0.019 15.6 3.5 5.5 7.8 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat PPTA PF01239.22 EGR28043.1 - 0.033 13.9 1.5 0.3 10.9 0.6 3.0 2 0 0 2 2 2 0 Protein prenyltransferase alpha subunit repeat TPR_3 PF07720.12 EGR28043.1 - 0.064 13.3 0.0 0.064 13.3 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGR28043.1 - 0.069 13.8 1.5 11 7.0 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat HflK_N PF12221.8 EGR28043.1 - 0.15 12.1 6.1 1.2 9.2 0.9 2.9 1 1 1 2 2 2 0 Bacterial membrane protein N terminal BTAD PF03704.17 EGR28043.1 - 0.29 11.6 7.2 0.77 10.2 0.0 3.3 3 1 0 3 3 2 0 Bacterial transcriptional activator domain PaREP1 PF05942.11 EGR28043.1 - 0.68 9.9 4.9 0.72 9.8 1.1 2.9 3 0 0 3 3 3 0 Archaeal PaREP1/PaREP8 family GST_N PF02798.20 EGR28044.1 - 6.9e-13 48.8 0.3 2.1e-12 47.2 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGR28044.1 - 3.5e-10 40.0 0.5 7.4e-10 38.9 0.5 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGR28044.1 - 5.9e-06 26.6 0.0 3.3e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGR28044.1 - 0.00036 20.8 0.0 0.00085 19.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGR28044.1 - 0.0015 18.5 0.0 0.0041 17.1 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain NUMOD1 PF07453.13 EGR28044.1 - 0.083 13.2 0.4 0.17 12.2 0.4 1.5 1 0 0 1 1 1 0 NUMOD1 domain DUF5495 PF17599.2 EGR28044.1 - 0.084 13.2 0.1 0.15 12.3 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5495) DrrA_P4M PF14860.6 EGR28044.1 - 0.099 12.5 0.4 2 8.3 0.3 2.4 1 1 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain AFP_2 PF18815.1 EGR28044.1 - 0.21 11.9 0.4 0.21 11.9 0.4 2.6 3 0 0 3 3 3 0 Bacterial antifreeze protein repeat AIRS PF00586.24 EGR28048.1 - 1.8e-06 28.5 0.5 2.8e-06 27.9 0.5 1.3 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain AIRS_C PF02769.22 EGR28048.1 - 0.03 14.5 0.0 0.053 13.7 0.0 1.4 1 0 0 1 1 1 0 AIR synthase related protein, C-terminal domain Pkinase PF00069.25 EGR28049.1 - 1.1e-54 185.6 4.1 1.1e-54 185.6 4.1 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28049.1 - 1.5e-29 103.1 0.4 2e-29 102.7 0.4 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR28049.1 - 2.8e-07 29.7 0.7 4.9e-07 28.9 0.2 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGR28049.1 - 1e-05 25.0 0.1 1.8e-05 24.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR28049.1 - 3e-05 24.0 0.0 0.0034 17.4 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGR28049.1 - 0.00011 22.0 2.8 0.24 11.0 0.1 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EGR28049.1 - 0.0041 16.5 0.2 0.011 15.1 0.2 1.8 1 1 0 1 1 1 1 Kinase-like EcKinase PF02958.20 EGR28049.1 - 0.0051 16.2 0.2 0.0051 16.2 0.2 2.1 1 1 0 2 2 2 1 Ecdysteroid kinase DUF1679 PF07914.11 EGR28049.1 - 0.011 14.7 7.7 0.026 13.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1679) bZIP_2 PF07716.15 EGR28049.1 - 1.2 9.3 3.5 0.71 10.0 0.7 2.1 2 0 0 2 2 2 0 Basic region leucine zipper Patatin PF01734.22 EGR28050.1 - 2.3e-07 31.2 0.0 3.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase DUF468 PF04318.12 EGR28050.1 - 0.022 15.5 0.1 0.061 14.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF468) DUF667 PF05018.13 EGR28052.1 - 2.6e-19 69.7 4.2 2.6e-19 69.7 4.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF667) WD40 PF00400.32 EGR28053.1 - 0.00033 21.4 0.3 0.86 10.6 0.0 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat Neuregulin PF02158.15 EGR28053.1 - 0.052 12.9 14.3 0.15 11.4 14.3 1.7 1 0 0 1 1 1 0 Neuregulin intracellular region Actin PF00022.19 EGR28054.1 - 6.8e-29 100.7 2.6 2e-28 99.1 2.6 1.8 1 1 0 1 1 1 1 Actin Actin_micro PF17003.5 EGR28054.1 - 0.0046 16.2 30.1 0.0036 16.5 24.9 2.8 1 1 1 2 2 2 1 Putative actin-like family FtsA PF14450.6 EGR28054.1 - 0.22 11.9 3.7 3.6 8.0 2.1 3.0 2 1 0 2 2 2 0 Cell division protein FtsA RRM_1 PF00076.22 EGR28055.1 - 6.1e-06 26.0 1.4 5.5e-05 22.9 0.2 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGR28055.1 - 0.013 15.5 13.6 0.026 14.5 1.3 2.8 2 1 0 2 2 2 0 RNA binding motif Limkain-b1 PF11608.8 EGR28055.1 - 0.042 13.9 0.2 0.32 11.1 0.0 2.3 2 0 0 2 2 2 0 Limkain b1 Y_phosphatase PF00102.27 EGR28056.1 - 2.2e-62 210.7 9.1 6.7e-62 209.1 9.1 1.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EGR28056.1 - 0.0094 15.8 0.1 0.039 13.8 0.0 2.1 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGR28056.1 - 0.045 13.7 0.0 0.073 13.0 0.0 1.5 1 1 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.12 EGR28056.1 - 0.068 12.8 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 EGR28056.1 - 6.9 6.8 7.8 6.7 6.8 0.3 3.1 2 1 1 3 3 3 0 Inositol hexakisphosphate Pkinase PF00069.25 EGR28060.1 - 6.9e-66 222.3 0.0 2.5e-65 220.5 0.0 2.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28060.1 - 2.5e-35 122.0 0.0 5.4e-35 120.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 EGR28060.1 - 8.1e-17 61.6 5.9 5.6e-11 42.9 1.6 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGR28060.1 - 1.5e-13 50.6 2.0 1.2e-07 31.8 0.0 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR28060.1 - 2.3e-12 45.9 5.2 0.0051 17.2 0.0 4.3 3 0 0 3 3 3 3 Ankyrin repeat Ank_4 PF13637.6 EGR28060.1 - 3.8e-12 46.5 5.6 4.2e-06 27.2 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGR28060.1 - 1.2e-11 44.5 5.0 0.002 18.5 0.1 3.9 3 0 0 3 3 3 3 Ankyrin repeat Kinase-like PF14531.6 EGR28060.1 - 0.00017 21.0 0.8 0.00036 19.9 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGR28060.1 - 0.17 11.8 0.1 0.44 10.4 0.1 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Alba PF01918.21 EGR28061.1 - 1.2e-05 25.0 2.7 1.7e-05 24.6 2.7 1.2 1 0 0 1 1 1 1 Alba SpoVS PF04232.12 EGR28061.1 - 0.0079 15.9 1.3 0.011 15.4 1.0 1.3 1 1 0 1 1 1 1 Stage V sporulation protein S (SpoVS) Lyase_1 PF00206.20 EGR28061.1 - 0.011 15.1 0.6 0.012 15.1 0.6 1.0 1 0 0 1 1 1 0 Lyase DUF4374 PF14298.6 EGR28061.1 - 0.028 13.2 0.1 0.03 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4374) DnaJ PF00226.31 EGR28062.1 - 1.9e-24 85.6 2.5 1.9e-24 85.6 2.5 2.6 2 1 0 2 2 2 1 DnaJ domain DUF1977 PF09320.11 EGR28062.1 - 1e-16 61.1 7.4 1e-16 61.1 7.4 2.7 3 1 0 3 3 3 1 Domain of unknown function (DUF1977) RPT PF13446.6 EGR28062.1 - 0.00015 21.6 1.5 0.034 14.1 0.0 2.8 2 0 0 2 2 2 2 A repeated domain in UCH-protein Paramyx_P_V_C PF03210.13 EGR28062.1 - 0.012 15.4 0.5 0.036 13.9 0.2 1.9 2 0 0 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal DUF3770 PF12603.8 EGR28062.1 - 0.66 9.4 8.4 0.2 11.1 1.9 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3770) LRR_4 PF12799.7 EGR28063.1 - 3.3e-10 40.0 4.7 4.3e-05 23.8 2.8 3.9 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGR28063.1 - 6.9e-06 25.7 3.7 11 5.8 0.5 3.2 2 1 0 2 2 2 1 Leucine rich repeat Mit_KHE1 PF10173.9 EGR28063.1 - 0.74 9.9 17.6 1.4 9.0 17.6 1.5 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related DUF1501 PF07394.12 EGR28063.1 - 1.8 7.6 4.9 2.3 7.2 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) TMEM89 PF15098.6 EGR28063.1 - 2.9 8.1 8.6 4.7 7.4 8.6 1.3 1 0 0 1 1 1 0 TMEM89 protein family SOBP PF15279.6 EGR28063.1 - 2.9 8.4 13.5 5.2 7.6 13.5 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein ORC_WH_C PF18137.1 EGR28063.1 - 5.9 7.0 12.4 0.89 9.6 8.4 1.7 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal GIDA_assoc PF13932.6 EGR28063.1 - 7.4 6.7 18.7 12 6.0 18.7 1.4 1 0 0 1 1 1 0 GidA associated domain Thymidylat_synt PF00303.19 EGR28064.1 - 1.3e-110 368.7 0.0 1.8e-110 368.3 0.0 1.1 1 0 0 1 1 1 1 Thymidylate synthase DHFR_1 PF00186.19 EGR28064.1 - 4.3e-16 59.0 0.0 8.1e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Dihydrofolate reductase RibD_C PF01872.17 EGR28064.1 - 0.028 14.2 0.0 0.044 13.6 0.0 1.2 1 0 0 1 1 1 0 RibD C-terminal domain cNMP_binding PF00027.29 EGR28065.1 - 4e-20 71.7 0.0 7.6e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Lactamase_B_6 PF16661.5 EGR28065.1 - 2.3e-15 56.6 0.1 5e-15 55.4 0.1 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 EGR28065.1 - 9.4e-13 48.6 0.1 1.5e-12 48.0 0.1 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Ion_trans_2 PF07885.16 EGR28065.1 - 3.5e-10 39.7 4.6 6.3e-10 38.9 4.6 1.4 1 0 0 1 1 1 1 Ion channel Lactamase_B_2 PF12706.7 EGR28065.1 - 4.7e-09 36.0 0.1 7.8e-09 35.3 0.1 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 EGR28065.1 - 6.1e-07 28.9 0.6 2.4e-06 27.0 0.5 2.1 1 1 0 1 1 1 1 Putative beta-lactamase-like family Beta-Casp PF10996.8 EGR28065.1 - 1.1e-05 25.7 0.1 3.1e-05 24.2 0.1 1.9 1 0 0 1 1 1 1 Beta-Casp domain Ion_trans PF00520.31 EGR28065.1 - 0.00012 21.4 4.1 0.00024 20.4 4.1 1.4 1 0 0 1 1 1 1 Ion transport protein Lactamase_B_3 PF13483.6 EGR28065.1 - 0.00039 20.4 1.0 0.05 13.5 0.1 2.9 1 1 1 2 2 2 2 Beta-lactamase superfamily domain CPSF73-100_C PF11718.8 EGR28065.1 - 0.0034 17.0 0.3 0.0091 15.6 0.3 1.7 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term AI-2E_transport PF01594.16 EGR28065.1 - 0.3 10.2 0.5 0.47 9.6 0.1 1.5 2 0 0 2 2 2 0 AI-2E family transporter Aminotran_3 PF00202.21 EGR28066.1 - 4.3e-64 216.7 0.0 6.1e-64 216.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Latarcin PF10279.9 EGR28066.1 - 0.11 12.9 0.0 6.4 7.3 0.0 3.5 3 1 0 3 3 3 0 Latarcin precursor Beta_elim_lyase PF01212.21 EGR28066.1 - 0.21 10.8 0.0 0.62 9.3 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase Nore1-SARAH PF16517.5 EGR28066.1 - 0.66 9.9 4.5 0.23 11.4 0.3 2.6 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain TAXi_N PF14543.6 EGR28067.1 - 2.6e-07 31.1 0.2 5.1e-07 30.1 0.2 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal CFAP91 PF14738.6 EGR28068.1 - 2.6e-48 163.9 12.0 2.6e-48 163.9 12.0 4.6 3 1 1 5 5 5 1 Cilia- and flagella-associated protein 91 Amj PF10997.8 EGR28068.1 - 0.85 8.9 4.7 0.75 9.1 0.6 2.3 2 0 0 2 2 2 0 Alternate to MurJ Pkinase PF00069.25 EGR28069.1 - 3.2e-47 161.1 2.5 2.2e-46 158.4 2.5 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28069.1 - 8e-33 113.8 0.3 1.6e-32 112.8 0.3 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR28069.1 - 3.7e-06 26.1 5.6 4.6e-06 25.8 5.6 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGR28069.1 - 5.6e-06 25.4 0.0 1.2e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGR28069.1 - 0.00012 21.5 0.2 0.0004 19.8 0.1 1.9 2 1 0 2 2 2 1 Kinase-like Glyco_hydro_4C PF11975.8 EGR28069.1 - 0.0027 17.8 0.5 0.0037 17.4 0.5 1.1 1 0 0 1 1 1 1 Family 4 glycosyl hydrolase C-terminal domain DUF2226 PF09987.9 EGR28069.1 - 0.007 15.8 1.6 0.014 14.7 1.6 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2226) Clr5 PF14420.6 EGR28069.1 - 0.093 13.0 1.0 0.21 11.9 0.2 2.0 2 0 0 2 2 2 0 Clr5 domain APH PF01636.23 EGR28069.1 - 0.11 12.4 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_6 PF13516.6 EGR28070.1 - 5.9e-10 38.4 11.0 0.83 9.9 0.0 7.3 6 3 0 6 6 6 4 Leucine Rich repeat LRR_4 PF12799.7 EGR28070.1 - 2.7e-05 24.4 21.4 0.17 12.3 3.0 4.2 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) T3RM_EcoP15I_C PF18273.1 EGR28070.1 - 0.06 13.7 2.2 4 7.8 0.1 2.8 1 1 2 3 3 3 0 Type III R-M EcoP15I C-terminal domain Radial_spoke PF04712.12 EGR28071.1 - 1.7e-16 60.3 4.4 1.5e-10 40.6 1.9 2.8 1 1 1 3 3 3 2 Radial spokehead-like protein EXS PF03124.14 EGR28072.1 - 3e-10 40.0 1.3 3.4e-10 39.8 1.3 1.2 1 0 0 1 1 1 1 EXS family DHHC PF01529.20 EGR28075.1 - 5.1e-33 114.0 18.8 5.1e-33 114.0 18.8 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF1774 PF08611.10 EGR28075.1 - 0.03 14.6 2.5 0.083 13.2 2.6 1.7 2 0 0 2 2 2 0 Fungal protein of unknown function (DUF1774) PSI PF01437.25 EGR28075.1 - 0.97 10.0 9.0 15 6.2 6.8 2.4 2 0 0 2 2 2 0 Plexin repeat Pkinase PF00069.25 EGR28076.1 - 0.0023 17.4 0.6 0.0023 17.4 0.6 2.3 1 1 1 2 2 2 1 Protein kinase domain Molybdopterin PF00384.22 EGR28078.1 - 1.1e-57 196.0 0.0 1.5e-56 192.2 0.0 2.3 1 1 0 1 1 1 1 Molybdopterin oxidoreductase NADH_dhqG_C PF09326.11 EGR28078.1 - 8.2e-19 68.0 0.4 3.2e-18 66.1 0.1 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2_4 PF13510.6 EGR28078.1 - 1.2e-16 60.5 0.1 2.2e-16 59.7 0.1 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 EGR28078.1 - 1e-15 56.9 0.1 1e-15 56.9 0.1 1.9 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer2 PF00111.27 EGR28078.1 - 3.5e-07 30.1 2.5 5.4e-07 29.5 0.3 2.2 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4 PF00037.27 EGR28078.1 - 0.095 12.6 1.9 11 6.1 0.3 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain TPP_enzyme_M PF00205.22 EGR28078.1 - 0.15 11.8 0.0 23 4.7 0.0 2.6 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Fer4_6 PF12837.7 EGR28078.1 - 9.7 6.5 8.7 0.85 9.8 0.5 2.8 3 0 0 3 3 3 0 4Fe-4S binding domain Ribosomal_S27e PF01667.17 EGR28079.1 - 1.8e-23 82.0 4.0 2.2e-23 81.7 4.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 EGR28079.1 - 0.0091 15.5 0.6 0.012 15.1 0.6 1.2 1 0 0 1 1 1 1 TFIIB zinc-binding DNA_pol3_beta_3 PF02768.15 EGR28079.1 - 0.069 13.0 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase III beta subunit, C-terminal domain zf-B_box PF00643.24 EGR28079.1 - 0.26 11.5 5.0 0.63 10.3 5.0 1.6 1 1 0 1 1 1 0 B-box zinc finger Methyltransf_23 PF13489.6 EGR28080.1 - 5e-14 52.5 1.1 5.9e-14 52.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGR28080.1 - 4.9e-07 30.4 0.0 1.4e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGR28080.1 - 1.2e-06 29.2 0.4 7e-06 26.7 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGR28080.1 - 6.4e-06 26.7 0.0 1.7e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Cbl_N PF02262.16 EGR28080.1 - 0.026 14.5 2.7 0.049 13.6 2.7 1.4 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 Methyltransf_31 PF13847.6 EGR28080.1 - 0.04 13.7 4.2 0.042 13.6 0.0 2.8 2 2 0 2 2 2 0 Methyltransferase domain Usg PF06233.12 EGR28080.1 - 0.045 13.9 1.7 3.2 8.0 0.4 2.5 2 0 0 2 2 2 0 Usg-like family Ndc1_Nup PF09531.10 EGR28080.1 - 0.48 9.1 2.3 0.49 9.0 2.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup WD40 PF00400.32 EGR28081.1 - 9.1e-14 51.7 1.1 5.7e-06 27.0 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF1899 PF08953.11 EGR28081.1 - 9.5e-11 41.4 0.0 1.9e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) ANAPC4_WD40 PF12894.7 EGR28081.1 - 7.9e-05 22.9 0.4 0.0012 19.1 0.3 2.6 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGR28081.1 - 0.0028 16.5 0.3 0.024 13.4 0.2 2.0 1 1 0 1 1 1 1 Nup133 N terminal like MORN PF02493.20 EGR28082.1 - 3.7e-21 73.7 41.1 0.00047 19.9 1.2 7.2 7 0 0 7 7 7 7 MORN repeat MORN_2 PF07661.13 EGR28082.1 - 2.7e-06 27.0 32.8 0.24 11.7 0.6 7.2 7 0 0 7 7 7 5 MORN repeat variant Ribosomal_S24e PF01282.19 EGR28082.1 - 2.2 8.3 5.8 13 5.8 0.3 2.8 3 0 0 3 3 3 0 Ribosomal protein S24e DUF3211 PF11485.8 EGR28082.1 - 8.7 6.6 7.1 12 6.1 0.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3211) Myb_DNA-binding PF00249.31 EGR28083.1 - 4.8e-26 90.7 2.2 6e-12 45.6 0.0 2.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGR28083.1 - 2.7e-20 72.4 0.9 1.5e-11 44.4 0.4 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGR28083.1 - 0.0004 20.2 0.3 0.036 14.0 0.0 2.1 1 1 1 2 2 2 2 Myb DNA-binding like SLIDE PF09111.10 EGR28083.1 - 0.0043 17.1 0.0 0.057 13.4 0.0 2.0 1 1 1 2 2 2 1 SLIDE Rap1_C PF11626.8 EGR28083.1 - 0.006 16.7 0.0 3.1 7.9 0.0 2.1 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain TauE PF01925.19 EGR28084.1 - 8.5e-23 81.2 11.6 5.8e-14 52.3 5.9 2.3 2 1 0 2 2 2 2 Sulfite exporter TauE/SafE DUF1676 PF07898.13 EGR28084.1 - 0.047 13.7 0.3 0.14 12.2 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) AKAP28 PF14469.6 EGR28085.1 - 3.3e-14 52.7 1.6 9.7e-14 51.2 1.6 1.8 1 0 0 1 1 1 1 28 kDa A-kinase anchor EF-hand_7 PF13499.6 EGR28085.1 - 1.7e-12 47.6 15.7 3.7e-06 27.3 0.0 4.9 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.6 EGR28085.1 - 8.1e-09 34.7 8.3 0.061 13.3 0.2 6.1 6 0 0 6 6 6 3 EF-hand domain EF-hand_1 PF00036.32 EGR28085.1 - 0.0002 20.7 11.9 0.06 12.9 0.0 6.1 6 0 0 6 6 6 2 EF hand EF-hand_8 PF13833.6 EGR28085.1 - 0.0017 18.2 8.2 0.0093 15.8 0.0 4.2 4 1 1 5 5 5 1 EF-hand domain pair EF-hand_4 PF12763.7 EGR28085.1 - 0.0028 17.6 1.6 1.4 9.0 0.3 2.9 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 EGR28085.1 - 0.081 13.3 5.3 12 6.3 0.2 3.9 3 1 1 4 4 4 0 EF-hand domain Pkinase PF00069.25 EGR28086.1 - 1.4e-66 224.6 1.2 1.4e-66 224.6 1.2 2.6 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28086.1 - 5.7e-34 117.6 0.0 1e-33 116.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR28086.1 - 0.002 17.5 0.0 0.0041 16.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR28086.1 - 0.0029 16.4 0.1 0.0029 16.4 0.1 2.4 2 1 0 3 3 3 1 Fungal protein kinase APH PF01636.23 EGR28086.1 - 0.22 11.4 0.0 0.91 9.4 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family SpoIIIAH PF12685.7 EGR28087.1 - 0.008 16.0 0.6 0.0088 15.9 0.6 1.1 1 0 0 1 1 1 1 SpoIIIAH-like protein ATP-grasp_4 PF13535.6 EGR28087.1 - 0.011 15.4 0.4 0.011 15.3 0.4 1.0 1 0 0 1 1 1 0 ATP-grasp domain HSCB_C PF07743.13 EGR28087.1 - 0.011 16.2 0.7 0.011 16.1 0.7 1.1 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain MORN PF02493.20 EGR28088.1 - 1.9e-49 162.7 64.6 7.6e-07 28.7 1.6 9.8 10 0 0 10 10 10 9 MORN repeat IQ PF00612.27 EGR28088.1 - 9.8e-05 21.8 1.1 0.00019 20.9 1.1 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif Cullin_binding PF03556.15 EGR28090.1 - 6e-28 97.7 5.8 6e-28 97.7 5.8 2.1 2 1 0 2 2 2 1 Cullin binding UBA_4 PF14555.6 EGR28090.1 - 1.4e-11 44.0 0.1 3.6e-10 39.5 0.0 2.6 2 0 0 2 2 2 1 UBA-like domain HBS1_N PF08938.10 EGR28090.1 - 0.022 15.0 0.1 0.6 10.4 0.1 2.8 3 0 0 3 3 3 0 HBS1 N-terminus Peptidase_M17 PF00883.21 EGR28091.1 - 6e-96 321.4 0.0 8.7e-96 320.8 0.0 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain RIH_assoc PF08454.11 EGR28091.1 - 0.0011 18.7 0.4 0.0035 17.2 0.4 1.8 1 0 0 1 1 1 1 RyR and IP3R Homology associated OHA PF14418.6 EGR28092.1 - 6.6e-18 64.3 1.1 6e-17 61.2 0.0 3.2 3 0 0 3 3 3 1 OST-HTH Associated domain OST-HTH PF12872.7 EGR28092.1 - 1.1e-10 41.1 0.1 4.4e-10 39.2 0.0 2.1 2 0 0 2 2 2 1 OST-HTH/LOTUS domain Gti1_Pac2 PF09729.9 EGR28092.1 - 0.77 9.8 9.4 0.3 11.1 4.2 2.3 2 1 0 2 2 2 0 Gti1/Pac2 family Pkinase PF00069.25 EGR28094.1 - 1.2e-73 247.7 0.1 1.5e-73 247.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28094.1 - 3.2e-47 161.0 0.0 3.9e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28094.1 - 1.6e-10 40.8 0.0 2.1e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR28094.1 - 7.9e-08 31.5 0.0 1.2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EGR28094.1 - 2.9e-06 27.0 2.1 1.9e-05 24.3 0.6 2.0 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 EGR28094.1 - 5.3e-05 23.3 0.1 0.00011 22.2 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR28094.1 - 0.00019 20.9 0.0 0.00028 20.3 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGR28094.1 - 0.00021 20.3 0.8 0.00021 20.3 0.8 1.8 1 1 1 2 2 2 1 Haspin like kinase domain PIP49_C PF12260.8 EGR28094.1 - 0.0048 16.5 0.0 0.0091 15.6 0.0 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 Choline_kinase PF01633.20 EGR28094.1 - 0.11 12.0 2.7 0.41 10.2 0.8 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase RepA_C PF04796.12 EGR28095.1 - 0.023 14.7 1.5 0.068 13.2 0.5 2.0 2 0 0 2 2 2 0 Plasmid encoded RepA protein COOH-NH2_lig PF14395.6 EGR28095.1 - 0.9 8.7 5.4 9.2 5.4 0.6 2.3 1 1 0 2 2 2 0 Phage phiEco32-like COOH.NH2 ligase-type 2 Kinesin PF00225.23 EGR28096.1 - 5.8e-65 219.4 13.7 5.8e-65 219.4 13.7 3.5 2 2 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGR28096.1 - 6.2e-38 130.1 13.3 6.2e-38 130.1 13.3 4.2 2 1 2 4 4 4 1 Microtubule binding Orn_Arg_deC_N PF02784.16 EGR28096.1 - 0.00058 19.3 1.5 0.0015 18.0 1.5 1.7 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain AAA_16 PF13191.6 EGR28096.1 - 0.023 15.1 0.1 0.15 12.4 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain PTPA PF03095.15 EGR28097.1 - 3.4e-108 361.7 2.6 3.9e-108 361.5 2.6 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein RRM_1 PF00076.22 EGR28098.1 - 5.7e-18 64.5 0.9 2e-09 37.1 0.1 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGR28098.1 - 0.00046 19.8 2.1 0.41 10.2 0.0 2.7 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HIGH_NTase1 PF05636.11 EGR28098.1 - 0.0021 17.3 0.9 0.0027 17.0 0.9 1.2 1 0 0 1 1 1 1 HIGH Nucleotidyl Transferase RNaseH_pPIWI_RE PF13032.6 EGR28098.1 - 0.006 16.5 0.3 0.0067 16.4 0.3 1.1 1 0 0 1 1 1 1 RNaseH domain of pPIWI_RE Methyltransf_34 PF11312.8 EGR28098.1 - 0.012 14.9 0.1 0.014 14.7 0.1 1.1 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase StbA PF06406.11 EGR28098.1 - 0.017 14.4 0.2 0.021 14.1 0.2 1.1 1 0 0 1 1 1 0 StbA protein Spt20 PF12090.8 EGR28098.1 - 0.061 12.9 11.0 0.083 12.5 11.0 1.3 1 0 0 1 1 1 0 Spt20 family DUF2722 PF10846.8 EGR28098.1 - 0.093 11.7 9.6 0.11 11.4 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Roughex PF06020.11 EGR28098.1 - 0.22 10.6 2.4 0.27 10.3 2.4 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Atg14 PF10186.9 EGR28098.1 - 0.23 10.5 8.0 0.29 10.2 8.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 PepSY_TM_like_2 PF16357.5 EGR28098.1 - 0.6 10.1 2.5 2.5 8.1 1.3 2.0 2 0 0 2 2 2 0 Putative PepSY_TM-like DUF4407 PF14362.6 EGR28098.1 - 1.2 8.4 6.0 1.7 7.9 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_23 PF13476.6 EGR28098.1 - 1.9 9.0 12.8 2.7 8.5 12.8 1.3 1 0 0 1 1 1 0 AAA domain Activator_LAG-3 PF11498.8 EGR28098.1 - 6.5 5.6 19.2 8.1 5.3 19.2 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 CLAMP PF14769.6 EGR28099.1 - 1.6e-24 86.2 7.6 2.5e-24 85.6 7.3 1.5 2 0 0 2 2 2 1 Flagellar C1a complex subunit C1a-32 NIF PF03031.18 EGR28100.1 - 1.7e-45 154.6 1.8 3.4e-45 153.6 1.8 1.5 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase fn3 PF00041.21 EGR28100.1 - 0.1 12.9 0.3 7.9 6.9 0.1 3.0 3 0 0 3 3 3 0 Fibronectin type III domain Thioredoxin_4 PF13462.6 EGR28101.1 - 1.3e-15 57.9 0.3 1.7e-15 57.6 0.3 1.1 1 0 0 1 1 1 1 Thioredoxin DSBA PF01323.20 EGR28101.1 - 1e-10 41.8 0.2 4.4e-09 36.4 0.2 2.2 1 1 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_14 PF18402.1 EGR28101.1 - 0.00049 20.1 1.4 0.00061 19.8 1.4 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Fer2_3 PF13085.6 EGR28101.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain HTH_56 PF18662.1 EGR28101.1 - 1.6 8.9 7.8 0.078 13.1 2.2 1.7 2 0 0 2 2 2 0 Cch helix turn helix domain FYRC PF05965.14 EGR28103.1 - 7e-16 58.2 0.0 1.9e-15 56.8 0.0 1.8 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 EGR28103.1 - 2e-11 43.5 0.0 4.7e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 F/Y-rich N-terminus Myb_DNA-binding PF00249.31 EGR28103.1 - 0.00017 21.7 0.2 0.0063 16.7 0.1 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain CHDCT2 PF08074.11 EGR28103.1 - 0.093 12.9 0.7 15 5.7 0.0 3.1 2 1 0 2 2 2 0 CHDCT2 (NUC038) domain RIB43A PF05914.12 EGR28104.1 - 8.4e-23 80.7 25.1 9e-23 80.6 25.1 1.0 1 0 0 1 1 1 1 RIB43A IFNGR1 PF07140.11 EGR28104.1 - 0.0051 16.9 0.3 0.011 15.9 0.2 1.5 1 1 0 1 1 1 1 Interferon gamma receptor (IFNGR1) Usher_TcfC PF17271.2 EGR28104.1 - 0.11 11.3 5.3 0.12 11.1 5.3 1.0 1 0 0 1 1 1 0 TcfC Usher-like barrel domain Hemolysin_N PF12563.8 EGR28104.1 - 0.12 12.0 2.9 0.15 11.7 2.9 1.2 1 0 0 1 1 1 0 Hemolytic toxin N terminal Pkinase PF00069.25 EGR28105.1 - 1.9e-36 125.8 0.0 1.9e-22 79.9 0.2 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28105.1 - 4.7e-12 45.7 0.1 5.6e-10 38.9 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase PCI PF01399.27 EGR28106.1 - 7.5e-14 52.1 3.7 7.5e-14 52.1 3.7 2.7 2 1 0 2 2 2 1 PCI domain RPN6_N PF18055.1 EGR28106.1 - 0.0032 17.8 3.8 0.0032 17.8 3.8 3.4 2 1 1 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain Mnd1 PF03962.15 EGR28106.1 - 0.26 11.6 6.9 0.68 10.3 0.1 3.5 3 0 0 3 3 3 0 Mnd1 HTH domain DUF3385 PF11865.8 EGR28106.1 - 4 7.3 10.7 0.27 11.1 3.9 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) PGG PF13962.6 EGR28107.1 - 0.0073 16.1 1.1 0.015 15.1 0.0 2.1 3 0 0 3 3 3 1 Domain of unknown function TLD PF07534.16 EGR28108.1 - 4e-19 69.2 3.5 5.6e-19 68.7 3.5 1.2 1 0 0 1 1 1 1 TLD zf-met PF12874.7 EGR28109.1 - 0.0031 17.8 0.2 0.0079 16.6 0.2 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGR28109.1 - 0.0043 17.3 0.9 0.016 15.5 0.9 2.0 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGR28109.1 - 0.054 13.8 4.1 0.087 13.2 3.4 1.8 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EGR28109.1 - 0.065 14.1 0.2 0.22 12.4 0.2 2.0 1 0 0 1 1 1 0 C2H2-type zinc finger Ran_BP1 PF00638.18 EGR28110.1 - 8.5e-31 106.8 0.8 8.5e-31 106.8 0.8 1.5 2 0 0 2 2 2 1 RanBP1 domain DUF1942 PF09167.11 EGR28110.1 - 0.028 14.4 0.0 0.042 13.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1942) Oxysterol_BP PF01237.18 EGR28111.1 - 1.3e-35 123.0 5.9 2.9e-34 118.5 5.9 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein YajC PF02699.15 EGR28111.1 - 0.056 13.3 0.3 0.15 11.9 0.3 1.7 1 0 0 1 1 1 0 Preprotein translocase subunit HSF_DNA-bind PF00447.17 EGR28112.1 - 5.7e-31 107.0 2.4 5.7e-31 107.0 2.4 1.9 2 1 0 2 2 2 1 HSF-type DNA-binding Ets PF00178.22 EGR28112.1 - 0.00046 20.6 0.6 0.0017 18.8 0.1 2.2 2 1 0 2 2 2 1 Ets-domain DUF4667 PF15700.5 EGR28112.1 - 0.024 14.7 0.4 0.038 14.1 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4667) CAP_N PF01213.19 EGR28113.1 - 1.6e-05 24.6 6.9 0.0025 17.3 5.3 2.1 1 1 1 2 2 2 2 Adenylate cyclase associated (CAP) N terminal Arf PF00025.21 EGR28114.1 - 4.1e-74 247.8 0.5 4.7e-74 247.6 0.5 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGR28114.1 - 1.7e-14 54.1 0.1 2.3e-14 53.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGR28114.1 - 6.1e-13 48.6 0.1 8e-13 48.2 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EGR28114.1 - 1.8e-12 47.2 0.0 1.9e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 EGR28114.1 - 8.1e-12 45.0 1.7 1.5e-07 31.0 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGR28114.1 - 7.9e-09 35.2 0.2 1.1e-08 34.8 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGR28114.1 - 3.2e-05 24.0 0.0 4.8e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EGR28114.1 - 0.023 14.0 0.1 0.059 12.7 0.0 1.6 2 0 0 2 2 2 0 6-phosphofructo-2-kinase Peptidase_C3 PF00548.20 EGR28114.1 - 0.064 13.2 0.0 2.6 7.9 0.0 2.1 1 1 1 2 2 2 0 3C cysteine protease (picornain 3C) Chromate_transp PF02417.15 EGR28115.1 - 1.5e-46 158.4 22.2 6e-27 94.7 9.6 2.2 2 0 0 2 2 2 2 Chromate transporter Pkinase PF00069.25 EGR28116.1 - 1.5e-11 44.2 0.2 9.4e-05 21.9 0.2 2.0 1 1 1 2 2 2 2 Protein kinase domain Feld-I_B PF09252.10 EGR28116.1 - 0.057 13.4 0.1 0.097 12.7 0.1 1.4 1 0 0 1 1 1 0 Allergen Fel d I-B chain Asp-B-Hydro_N PF05279.11 EGR28117.1 - 2.1 8.3 33.9 3.2 7.8 33.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CDC45 PF02724.14 EGR28117.1 - 3.2 5.9 26.9 4.2 5.5 26.9 1.1 1 0 0 1 1 1 0 CDC45-like protein UCH PF00443.29 EGR28119.1 - 2.1e-47 161.8 18.7 2.1e-47 161.8 18.7 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR28119.1 - 1.3e-31 110.4 24.9 1.3e-31 110.4 24.9 2.9 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Secretin_N_2 PF07655.13 EGR28119.1 - 5.7 7.5 11.5 15 6.3 8.2 3.0 2 0 0 2 2 2 0 Secretin N-terminal domain DUF2538 PF10804.8 EGR28121.1 - 2.7 7.8 9.7 2.6 7.8 2.4 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF2538) Fumble PF03630.14 EGR28121.1 - 6.1 5.9 10.5 13 4.8 10.5 1.6 1 1 0 1 1 1 0 Fumble AAA_12 PF13087.6 EGR28123.1 - 4.8e-58 196.1 3.8 7.1e-58 195.5 3.8 1.3 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EGR28123.1 - 0.0002 21.2 0.6 0.00082 19.2 0.0 2.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 EGR28123.1 - 0.039 13.8 0.0 0.072 12.9 0.0 1.4 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Pkinase PF00069.25 EGR28124.1 - 6.1e-71 238.9 0.0 7.1e-71 238.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28124.1 - 1.4e-40 139.2 0.0 1.8e-40 138.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28124.1 - 3.7e-06 26.5 0.0 6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PT-HINT PF07591.11 EGR28124.1 - 0.021 15.1 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 Pretoxin HINT domain Arf PF00025.21 EGR28125.1 - 4.5e-43 146.7 0.4 5.3e-43 146.5 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGR28125.1 - 1.5e-22 80.0 0.0 1.8e-22 79.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR28125.1 - 1e-17 64.4 0.1 7.4e-17 61.7 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGR28125.1 - 2.9e-11 43.4 0.0 7.3e-11 42.2 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGR28125.1 - 1.4e-09 37.7 0.0 1.7e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGR28125.1 - 4.6e-09 35.9 0.9 4.4e-06 26.1 0.1 2.9 1 1 2 3 3 3 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGR28125.1 - 1.3e-07 31.2 0.0 1.4e-07 31.1 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGR28125.1 - 3.7e-06 26.6 0.0 0.00019 21.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGR28125.1 - 0.00093 19.1 0.3 0.22 11.4 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EGR28125.1 - 0.0012 19.1 0.2 0.068 13.4 0.1 2.6 1 1 1 2 2 2 1 AAA domain Dynamin_N PF00350.23 EGR28125.1 - 0.014 15.5 0.3 0.47 10.5 0.1 2.3 1 1 1 2 2 2 0 Dynamin family AAA_14 PF13173.6 EGR28125.1 - 0.016 15.2 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGR28125.1 - 0.046 14.2 0.2 0.081 13.4 0.2 1.6 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 EGR28125.1 - 0.049 13.2 2.6 0.52 9.8 2.6 2.4 1 1 0 1 1 1 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 EGR28125.1 - 0.093 12.5 0.1 2.3 7.9 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein TatD_DNase PF01026.21 EGR28126.1 - 1.9e-47 161.8 0.0 6.1e-46 156.9 0.0 2.0 1 1 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 EGR28126.1 - 0.11 12.2 0.0 10 5.8 0.0 2.2 1 1 1 2 2 2 0 Amidohydrolase DUF226 PF02890.14 EGR28127.1 - 0.022 14.8 0.1 0.03 14.3 0.1 1.3 1 0 0 1 1 1 0 Borrelia family of unknown function DUF226 Yip1 PF04893.17 EGR28128.1 - 4.7e-15 55.7 2.2 5.9e-15 55.4 2.2 1.1 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 EGR28128.1 - 0.00038 20.3 2.5 0.00048 19.9 2.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1282) Proteasome PF00227.26 EGR28129.1 - 7e-52 175.7 0.3 8.5e-52 175.4 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGR28129.1 - 1.6e-09 37.3 0.1 4e-09 36.0 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature MAF_flag10 PF01973.18 EGR28130.1 - 0.00024 20.9 0.3 0.00024 20.9 0.3 3.0 2 1 1 3 3 3 1 Protein of unknown function DUF115 Pkinase PF00069.25 EGR28131.1 - 8.2e-48 163.1 0.8 2.8e-46 158.0 0.8 2.3 1 1 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.32 EGR28131.1 - 8.3e-22 75.1 9.3 4.8e-05 22.6 0.2 5.1 5 0 0 5 5 5 4 EF hand Pkinase_Tyr PF07714.17 EGR28131.1 - 8.3e-22 77.7 0.1 2.9e-21 75.9 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EGR28131.1 - 1.6e-21 76.6 6.0 6.3e-11 42.6 1.2 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGR28131.1 - 1e-18 65.9 10.9 5.5e-06 25.6 0.1 4.8 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 EGR28131.1 - 1.9e-18 64.7 3.9 0.00019 21.1 0.0 5.1 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 EGR28131.1 - 3.4e-15 55.6 6.6 4.2e-05 23.3 0.2 3.9 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_10 PF14788.6 EGR28131.1 - 1.3e-07 31.4 4.9 0.00016 21.4 1.2 3.7 2 1 1 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 EGR28131.1 - 3.2e-05 24.2 2.9 0.03 14.6 0.1 2.6 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region MAPEG PF01124.18 EGR28131.1 - 0.00017 21.5 0.1 0.00034 20.5 0.1 1.5 1 0 0 1 1 1 1 MAPEG family Kinase-like PF14531.6 EGR28131.1 - 0.00024 20.5 0.0 0.0009 18.6 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR28131.1 - 0.00066 19.1 1.2 0.0025 17.2 0.3 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_11 PF08976.11 EGR28131.1 - 0.0028 18.5 1.0 5.5 7.9 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain EF-hand_4 PF12763.7 EGR28131.1 - 0.0031 17.4 6.9 0.12 12.4 1.0 3.3 2 1 1 4 4 4 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 EGR28131.1 - 0.035 14.3 5.7 2.1 8.6 0.9 3.5 1 1 2 3 3 3 0 Dockerin type I domain DUF1002 PF06207.11 EGR28131.1 - 9.5 5.7 8.7 0.67 9.4 1.8 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1002) MMR_HSR1 PF01926.23 EGR28132.1 - 1.3e-42 144.4 4.8 7.2e-21 74.4 0.7 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 EGR28132.1 - 6.3e-29 100.1 0.3 1.4e-26 92.6 0.2 2.8 2 0 0 2 2 2 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 EGR28132.1 - 3.9e-22 78.5 1.4 5.2e-13 48.8 0.6 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 EGR28132.1 - 1.5e-11 44.3 12.5 6.3e-08 32.4 4.8 5.1 2 2 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGR28132.1 - 7.3e-10 39.0 8.6 5e-05 23.3 0.5 3.9 4 0 0 4 4 4 3 RsgA GTPase Ras PF00071.22 EGR28132.1 - 1.6e-09 37.5 8.3 0.0002 21.0 0.2 2.7 2 0 0 2 2 2 2 Ras family AIG1 PF04548.16 EGR28132.1 - 6.7e-09 35.4 3.0 3.6e-08 33.0 1.1 3.4 4 0 0 4 4 4 2 AIG1 family Dynamin_N PF00350.23 EGR28132.1 - 1.7e-08 34.7 16.9 9.5e-05 22.5 0.0 5.2 3 2 2 5 5 5 2 Dynamin family Roc PF08477.13 EGR28132.1 - 2.1e-06 28.0 16.0 0.00041 20.6 0.3 4.8 4 2 0 4 4 4 2 Ras of Complex, Roc, domain of DAPkinase TniB PF05621.11 EGR28132.1 - 8.2e-05 22.1 0.5 0.066 12.6 0.1 2.6 2 0 0 2 2 2 2 Bacterial TniB protein RNA_helicase PF00910.22 EGR28132.1 - 0.00061 20.2 4.5 0.91 9.9 0.1 3.4 3 0 0 3 3 3 2 RNA helicase SRPRB PF09439.10 EGR28132.1 - 0.0015 18.0 18.9 0.0056 16.1 3.0 3.4 2 1 1 3 3 3 2 Signal recognition particle receptor beta subunit Arf PF00025.21 EGR28132.1 - 0.015 14.7 12.7 0.02 14.4 0.7 4.0 4 1 0 4 4 4 0 ADP-ribosylation factor family ABC_tran PF00005.27 EGR28132.1 - 0.018 15.6 1.1 0.018 15.6 1.1 3.2 2 1 1 3 3 3 0 ABC transporter AAA_29 PF13555.6 EGR28132.1 - 0.028 14.2 0.1 0.68 9.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 EGR28132.1 - 0.051 13.3 2.0 1.7 8.4 0.1 3.0 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 EGR28132.1 - 0.11 12.8 0.1 7.2 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EGR28132.1 - 0.16 11.5 6.7 1.4 8.5 0.6 3.4 2 1 1 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EGR28132.1 - 0.26 11.8 10.5 5.2 7.6 0.0 4.3 3 1 2 5 5 5 0 AAA domain PNPase PF03726.14 EGR28132.1 - 6.2 7.4 9.8 1.7 9.2 5.6 2.4 2 0 0 2 2 1 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain TPR_1 PF00515.28 EGR28133.1 - 0.67 9.9 10.5 0.35 10.8 1.6 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Pkinase PF00069.25 EGR28134.1 - 1.5e-15 57.2 0.1 2e-15 56.9 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28134.1 - 2.1e-12 46.9 0.1 2.3e-12 46.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28134.1 - 3e-07 30.0 0.0 3.6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EGR28134.1 - 0.013 14.6 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 EGR28134.1 - 0.1 12.2 1.5 0.25 10.9 0.1 2.3 1 1 2 3 3 3 0 RIO1 family Myb_DNA-binding PF00249.31 EGR28135.1 - 4.8e-31 106.7 4.5 1.8e-16 60.1 0.1 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGR28135.1 - 3.5e-21 75.2 7.0 7.5e-13 48.5 1.0 3.4 2 2 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGR28135.1 - 2.1e-07 30.7 0.0 2.1e-07 30.7 0.0 2.4 2 1 0 2 2 2 1 Myb DNA-binding like Sigma70_r4_2 PF08281.12 EGR28135.1 - 0.0066 16.1 0.0 0.013 15.1 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 Myb_DNA-bind_4 PF13837.6 EGR28135.1 - 0.016 15.5 0.4 0.016 15.5 0.4 3.5 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 EGR28135.1 - 0.017 15.3 3.3 0.3 11.3 0.1 2.8 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 MEKHLA PF08670.11 EGR28135.1 - 0.025 14.5 0.1 0.039 13.8 0.1 1.3 1 0 0 1 1 1 0 MEKHLA domain Ribonuc_2-5A PF06479.12 EGR28135.1 - 0.04 14.1 5.0 0.077 13.2 2.5 2.2 2 1 0 2 2 2 0 Ribonuclease 2-5A SLIDE PF09111.10 EGR28135.1 - 1.8 8.6 13.0 1.4 8.9 0.1 3.6 3 1 1 4 4 4 0 SLIDE Myb_DNA-bind_2 PF08914.11 EGR28135.1 - 2.2 8.6 5.7 18 5.6 0.1 3.5 3 2 0 3 3 3 0 Rap1 Myb domain Aa_trans PF01490.18 EGR28138.1 - 3.8e-45 154.3 47.6 1.3e-43 149.3 47.6 2.0 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Band_7 PF01145.25 EGR28140.1 - 5.4e-24 85.2 0.0 9.1e-24 84.4 0.0 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Rsm22 PF09243.10 EGR28141.1 - 2.3e-72 243.6 0.0 3.6e-72 243.0 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_11 PF08241.12 EGR28141.1 - 4.9e-09 36.7 0.0 1.4e-07 32.1 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGR28141.1 - 5.3e-08 32.9 0.0 1.1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGR28141.1 - 3.2e-07 31.0 1.1 2.1e-06 28.4 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGR28141.1 - 9.1e-07 29.5 0.0 9.6e-06 26.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGR28141.1 - 5.8e-06 25.8 0.1 4.1e-05 23.0 0.0 2.3 3 0 0 3 3 3 1 ubiE/COQ5 methyltransferase family Pex14_N PF04695.13 EGR28141.1 - 9.4e-05 23.1 2.4 0.00016 22.4 2.4 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DHHA1 PF02272.19 EGR28141.1 - 3.7 7.9 7.2 15 6.0 6.6 2.1 2 0 0 2 2 2 0 DHHA1 domain MORN PF02493.20 EGR28142.1 - 8.3e-13 47.4 23.3 1.7e-07 30.7 0.7 6.8 7 0 0 7 7 7 4 MORN repeat Pkinase PF00069.25 EGR28142.1 - 4.1e-09 36.2 1.0 4.1e-09 36.2 1.0 2.3 2 1 0 2 2 2 1 Protein kinase domain MORN_2 PF07661.13 EGR28142.1 - 8 7.0 8.2 2.8 8.4 0.3 4.3 3 0 0 3 3 3 0 MORN repeat variant Peptidase_M18 PF02127.15 EGR28145.1 - 6.3e-84 282.3 0.5 8.4e-84 281.8 0.5 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EGR28145.1 - 1.6e-09 37.3 0.0 6e-05 22.2 0.0 2.1 2 0 0 2 2 2 2 M42 glutamyl aminopeptidase PDU_like PF15953.5 EGR28145.1 - 0.12 12.5 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative propanediol utilisation Pkinase PF00069.25 EGR28146.1 - 8.5e-69 231.8 0.0 1.2e-68 231.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28146.1 - 1.1e-39 136.3 0.0 1.5e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Myosin_TH1 PF06017.13 EGR28146.1 - 2.1e-11 43.8 0.8 3.8e-11 43.0 0.8 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Kinase-like PF14531.6 EGR28146.1 - 0.0013 18.1 0.1 0.031 13.6 0.0 2.3 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGR28146.1 - 0.012 14.6 0.3 0.016 14.2 0.3 1.4 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_C PF00433.24 EGR28146.1 - 0.14 12.8 1.1 0.28 11.9 1.1 1.4 1 0 0 1 1 1 0 Protein kinase C terminal domain APH PF01636.23 EGR28146.1 - 0.17 11.8 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RINGv PF12906.7 EGR28147.1 - 9.2e-15 54.5 1.5 2.3e-14 53.2 1.5 1.7 1 0 0 1 1 1 1 RING-variant domain FHA PF00498.26 EGR28147.1 - 1.6e-12 47.6 0.1 4.5e-12 46.2 0.1 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGR28147.1 - 9.7e-06 25.8 0.0 2.4e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_2 PF13639.6 EGR28147.1 - 0.00024 21.3 2.1 0.00024 21.3 2.1 2.2 2 1 0 2 2 2 1 Ring finger domain FANCL_C PF11793.8 EGR28147.1 - 0.014 15.6 3.2 0.048 13.8 3.1 2.0 1 1 1 2 2 2 0 FANCL C-terminal domain p450 PF00067.22 EGR28147.1 - 0.016 14.0 0.1 0.023 13.5 0.1 1.2 1 0 0 1 1 1 0 Cytochrome P450 zf-RING_11 PF17123.5 EGR28147.1 - 0.3 10.9 6.8 0.21 11.4 4.1 2.3 2 0 0 2 2 2 0 RING-like zinc finger TetR_C_29 PF17938.1 EGR28147.1 - 4.3 7.4 4.9 17 5.5 0.3 2.6 2 1 1 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Cation_ATPase_C PF00689.21 EGR28148.1 - 1e-38 132.9 9.3 1e-38 132.9 9.3 3.5 3 1 1 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGR28148.1 - 3.3e-20 73.3 0.0 7.2e-20 72.2 0.0 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGR28148.1 - 3.1e-12 46.4 0.4 3.1e-12 46.4 0.4 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGR28148.1 - 3.4e-07 30.2 0.9 8.1e-07 29.0 0.1 2.0 2 0 0 2 2 2 1 Cation transport ATPase (P-type) HAD PF12710.7 EGR28148.1 - 0.11 12.9 0.0 0.2 12.0 0.0 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Cpn60_TCP1 PF00118.24 EGR28150.1 - 2.6e-153 511.2 15.9 3e-153 511.0 15.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family GlcNAc-1_reg PF18440.1 EGR28150.1 - 0.067 13.4 0.2 14 6.0 0.0 3.0 2 0 0 2 2 2 0 Putative GlcNAc-1 phosphotransferase regulatory domain Pkinase PF00069.25 EGR28152.1 - 5e-73 245.7 0.9 1.5e-72 244.2 0.9 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28152.1 - 2.3e-41 141.8 0.0 4.5e-41 140.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EGR28152.1 - 7.5e-35 118.9 5.8 1.1e-18 67.2 0.8 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 EGR28152.1 - 3.4e-11 43.0 0.0 2.7e-09 36.8 0.0 2.6 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR28152.1 - 8e-06 24.9 0.1 8e-06 24.9 0.1 1.8 2 0 0 2 2 2 1 Fungal protein kinase Nudc_N PF14050.6 EGR28153.1 - 0.054 13.5 0.7 0.18 11.8 0.3 1.9 2 0 0 2 2 2 0 N-terminal conserved domain of Nudc. Pkinase PF00069.25 EGR28155.1 - 1.1e-70 238.0 0.8 1.5e-70 237.6 0.8 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28155.1 - 4e-36 124.6 0.1 5.7e-36 124.1 0.1 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR28155.1 - 8.1e-07 28.3 0.5 8.1e-07 28.3 0.5 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EGR28155.1 - 0.0002 20.8 0.0 0.00048 19.5 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR28155.1 - 0.0059 16.0 1.0 0.0059 16.0 1.0 2.4 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR28155.1 - 0.021 14.7 0.0 0.5 10.2 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family EF-G-binding_N PF07299.11 EGR28155.1 - 0.084 13.4 2.2 0.6 10.7 0.4 2.8 2 1 0 2 2 2 0 Elongation factor G-binding protein, N-terminal Ras PF00071.22 EGR28156.1 - 3.5e-45 153.5 1.1 4.8e-42 143.3 1.1 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGR28156.1 - 2.9e-32 111.4 5.2 1.1e-31 109.5 0.1 2.9 2 2 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR28156.1 - 2.8e-14 53.0 0.3 3.2e-09 36.5 0.0 2.1 1 1 1 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGR28156.1 - 5.1e-10 39.1 0.4 8.2e-10 38.4 0.4 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGR28156.1 - 6.6e-07 29.4 0.0 1.2e-06 28.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGR28156.1 - 0.0001 22.3 0.1 0.13 12.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EGR28156.1 - 0.0017 17.8 0.3 0.0083 15.6 0.0 2.0 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EGR28156.1 - 0.0018 17.8 0.0 0.31 10.5 0.0 2.2 2 0 0 2 2 2 2 Ferrous iron transport protein B Dynamin_N PF00350.23 EGR28156.1 - 0.056 13.5 0.0 0.056 13.5 0.0 3.0 2 2 0 3 3 3 0 Dynamin family DUF2681 PF10883.8 EGR28156.1 - 0.1 13.0 11.0 0.38 11.2 7.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) ABC_membrane_2 PF06472.15 EGR28157.1 - 7.6e-82 274.7 2.5 1.2e-81 274.1 2.5 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EGR28157.1 - 7.1e-20 71.9 0.0 1.7e-19 70.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGR28157.1 - 2.1e-07 31.0 0.0 4.7e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGR28157.1 - 0.00012 21.7 2.2 0.0006 19.3 0.3 2.6 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_7 PF12775.7 EGR28157.1 - 0.0079 15.7 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_29 PF13555.6 EGR28157.1 - 0.035 13.8 0.1 0.088 12.6 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EGR28157.1 - 0.087 13.2 0.5 0.21 12.0 0.1 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 EGR28157.1 - 0.088 13.3 0.1 0.088 13.3 0.1 2.8 3 1 0 3 3 3 0 AAA domain TERT_thumb PF17984.1 EGR28157.1 - 0.12 12.3 1.2 2.4 8.0 0.2 2.4 2 0 0 2 2 2 0 Telomerase reverse transcriptase thumb DNA binding domain CBF PF03914.17 EGR28157.1 - 0.18 11.9 0.1 0.47 10.5 0.0 1.9 2 0 0 2 2 2 0 CBF/Mak21 family Pkinase PF00069.25 EGR28158.1 - 1.6e-46 158.8 0.8 2.1e-46 158.5 0.8 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28158.1 - 2e-26 92.9 0.1 2.9e-26 92.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR28158.1 - 0.00092 18.6 0.1 0.0013 18.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Fe_hyd_SSU PF02256.17 EGR28158.1 - 0.039 14.0 0.5 0.42 10.7 0.0 2.3 2 0 0 2 2 2 0 Iron hydrogenase small subunit YrbL-PhoP_reg PF10707.9 EGR28158.1 - 0.051 13.1 1.6 0.091 12.3 1.6 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL DUF5600 PF18150.1 EGR28158.1 - 0.057 14.0 0.5 0.15 12.7 0.2 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF5600) FTA2 PF13095.6 EGR28158.1 - 0.062 12.9 3.7 1.1 8.8 0.2 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGR28158.1 - 0.26 11.2 0.0 0.54 10.1 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family MFAP1 PF06991.11 EGR28159.1 - 8.2e-20 71.6 17.7 8.2e-20 71.6 17.7 3.1 1 1 2 3 3 3 1 Microfibril-associated/Pre-mRNA processing Caldesmon PF02029.15 EGR28159.1 - 6.5 5.4 55.1 8.3 5.0 55.1 1.2 1 0 0 1 1 1 0 Caldesmon MFAP1 PF06991.11 EGR28160.1 - 1.2e-30 107.0 7.5 1.9e-30 106.3 7.5 1.3 1 0 0 1 1 1 1 Microfibril-associated/Pre-mRNA processing Cyt-b5 PF00173.28 EGR28161.1 - 1e-20 73.7 0.0 1.3e-20 73.3 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EAGR_box PF16713.5 EGR28162.1 - 0.078 12.7 2.5 10 5.9 0.1 3.0 2 0 0 2 2 2 0 Enriched in aromatic and glycine Residues box GAS PF13851.6 EGR28163.1 - 2.4e-48 164.2 37.9 2.4e-48 164.2 37.9 4.8 4 1 1 5 5 5 1 Growth-arrest specific micro-tubule binding EF-hand_8 PF13833.6 EGR28163.1 - 6e-07 29.2 7.4 0.00034 20.4 0.4 4.6 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR28163.1 - 0.05 13.2 11.6 1.4 8.6 0.4 4.7 5 0 0 5 5 5 0 EF hand DUF1133 PF06576.11 EGR28163.1 - 1.3 8.4 4.5 0.92 8.9 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1133) EF-hand_6 PF13405.6 EGR28163.1 - 2.6 8.2 10.8 6.3 7.0 0.7 5.0 5 0 0 5 5 5 0 EF-hand domain Tubulin PF00091.25 EGR28164.1 - 9.8e-69 231.5 0.0 1.8e-68 230.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGR28164.1 - 7.1e-42 142.5 0.1 1.1e-41 142.0 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGR28164.1 - 0.00023 21.5 0.0 0.00058 20.2 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EGR28164.1 - 0.0071 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EGR28164.1 - 0.0087 15.3 0.1 0.022 14.0 0.0 1.6 2 0 0 2 2 2 1 Tubulin like IFT46_B_C PF12317.8 EGR28165.1 - 3.4e-87 291.6 8.2 6e-87 290.8 8.2 1.4 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal MORN PF02493.20 EGR28166.1 - 9.9e-51 166.7 81.7 8.4e-09 34.8 1.9 10.8 11 0 0 11 11 11 9 MORN repeat DUF3413 PF11893.8 EGR28166.1 - 1.1 8.3 2.3 1.6 7.8 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3413) Tudor_2 PF18104.1 EGR28166.1 - 3.1 7.6 26.1 2.9 7.6 0.8 7.3 8 0 0 8 8 8 0 Jumonji domain-containing protein 2A Tudor domain CTP_transf_like PF01467.26 EGR28167.1 - 1.2e-25 90.3 0.0 1.6e-25 90.0 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like FAD_syn PF06574.12 EGR28167.1 - 0.043 13.7 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 FAD synthetase DUF5639 PF18690.1 EGR28167.1 - 0.16 12.1 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5639) U-box PF04564.15 EGR28168.1 - 2.3e-18 66.1 0.0 4.3e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 EGR28168.1 - 0.00076 19.6 0.1 0.0019 18.3 0.1 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 EGR28168.1 - 0.00082 19.1 0.1 0.0038 17.0 0.1 2.1 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Na_trans_assoc PF06512.13 EGR28168.1 - 0.0094 16.3 0.7 0.01 16.1 0.7 1.2 1 0 0 1 1 1 1 Sodium ion transport-associated Ank_2 PF12796.7 EGR28169.1 - 6.2e-07 29.9 0.0 1e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGR28169.1 - 5.1e-05 23.5 0.1 1.2 9.7 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EGR28169.1 - 0.00013 22.1 0.1 0.49 11.1 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EGR28169.1 - 0.00035 21.1 0.1 0.16 12.6 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGR28169.1 - 0.0018 18.6 0.1 0.11 12.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Peptidase_C13 PF01650.18 EGR28170.1 - 7.9e-22 78.0 0.3 1.3e-21 77.3 0.3 1.4 1 0 0 1 1 1 1 Peptidase C13 family Jacalin PF01419.17 EGR28170.1 - 3.4e-08 33.5 0.4 3.4e-08 33.5 0.4 2.1 2 1 0 2 2 2 1 Jacalin-like lectin domain DUF3970 PF13113.6 EGR28170.1 - 0.05 13.8 0.0 0.18 12.0 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3970) BUD22 PF09073.10 EGR28170.1 - 0.1 11.9 0.0 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 BUD22 Pkinase PF00069.25 EGR28171.1 - 2.9e-73 246.5 0.6 3.3e-73 246.3 0.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28171.1 - 5.9e-49 166.7 0.0 7.2e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28171.1 - 1.2e-05 24.7 0.1 6.8e-05 22.3 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR28171.1 - 0.00027 19.8 0.2 0.00076 18.4 0.0 1.7 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EGR28171.1 - 0.0018 17.9 1.9 0.0049 16.5 1.5 1.9 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGR28171.1 - 0.025 13.9 0.0 0.045 13.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_7 PF13499.6 EGR28172.1 - 6.6e-28 97.0 1.7 5.7e-13 49.1 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR28172.1 - 2.6e-26 89.2 1.0 6.8e-06 25.3 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGR28172.1 - 8.6e-21 72.1 1.2 6.3e-06 25.7 0.2 4.3 3 1 1 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGR28172.1 - 1.2e-18 66.7 0.8 7.7e-08 32.1 0.0 4.1 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 EGR28172.1 - 1e-14 54.5 0.0 3.7e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGR28172.1 - 1.2e-09 37.2 1.4 0.011 15.2 0.0 3.6 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 EGR28172.1 - 0.0017 18.6 0.1 0.49 10.7 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF3349 PF11829.8 EGR28172.1 - 0.034 14.9 0.3 11 6.8 0.0 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) UPF0154 PF03672.13 EGR28172.1 - 0.05 13.6 0.1 0.18 11.9 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.10 EGR28172.1 - 0.056 13.5 0.6 2.5 8.2 0.1 2.6 2 2 0 2 2 2 0 Ca2+ insensitive EF hand DUF5580 PF17743.1 EGR28172.1 - 0.063 11.8 0.0 0.072 11.6 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) EF-hand_11 PF08976.11 EGR28172.1 - 0.08 13.8 0.1 5.4 7.9 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain ETAA1 PF15350.6 EGR28172.1 - 0.13 10.6 0.8 0.16 10.2 0.8 1.1 1 0 0 1 1 1 0 Ewing's tumour-associated antigen 1 homologue IPP-2 PF04979.14 EGR28173.1 - 6e-09 36.7 6.2 6.9e-09 36.5 6.2 1.1 1 0 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) NCD3G PF07562.14 EGR28174.1 - 1.4e-05 24.9 10.6 1.4e-05 24.9 10.6 4.9 4 0 0 4 4 4 1 Nine Cysteines Domain of family 3 GPCR Furin-like_2 PF15913.5 EGR28174.1 - 0.0078 16.4 23.3 0.0078 16.4 23.3 4.0 2 1 2 4 4 4 1 Furin-like repeat, cysteine-rich Ribosomal_S8 PF00410.19 EGR28175.1 - 4.3e-11 42.9 0.0 5.9e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 FAST_2 PF08368.12 EGR28175.1 - 0.1 13.4 0.0 7.3 7.4 0.0 2.6 1 1 2 3 3 3 0 FAST kinase-like protein, subdomain 2 Pkinase PF00069.25 EGR28176.1 - 7.4e-49 166.5 1.0 7.4e-49 166.5 1.0 7.6 5 4 1 6 6 6 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28176.1 - 9.3e-22 77.5 12.9 3e-15 56.2 0.4 4.7 2 1 2 4 4 4 2 Protein tyrosine kinase Radical_SAM PF04055.21 EGR28176.1 - 0.0058 17.0 3.0 0.024 15.0 0.2 3.0 3 1 0 3 3 3 1 Radical SAM superfamily Herpes_UL49_2 PF04823.12 EGR28176.1 - 0.025 14.7 0.8 0.93 9.6 0.0 2.5 2 0 0 2 2 2 0 Herpesvirus UL49 tegument protein APH PF01636.23 EGR28176.1 - 0.042 13.8 0.1 0.079 12.9 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mito_carr PF00153.27 EGR28177.1 - 3.6e-56 187.1 0.3 6.3e-18 64.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGR28177.1 - 0.0013 17.9 0.1 0.034 13.3 0.0 2.2 1 1 1 2 2 2 2 Gammaproteobacterial serine protease Phage_holin_3_3 PF16083.5 EGR28177.1 - 0.008 16.3 0.2 1.2 9.3 0.0 2.9 3 0 0 3 3 3 1 LydA holin phage, holin superfamily III YabA PF06156.13 EGR28178.1 - 0.6 10.8 18.7 1.1 9.9 14.0 2.9 2 1 0 2 2 2 0 Initiation control protein YabA PI_PP_I PF18363.1 EGR28178.1 - 3.9 7.7 9.6 0.15 12.3 2.1 2.3 2 1 1 3 3 3 0 Phosphoinositide phosphatase insertion domain GHMP_kinases_N PF00288.26 EGR28179.1 - 3.3e-05 24.0 0.2 6.9e-05 23.0 0.2 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain MDD_C PF18376.1 EGR28179.1 - 0.0045 16.7 2.3 1.6 8.4 0.0 3.1 2 1 2 4 4 4 2 Mevalonate 5-diphosphate decarboxylase C-terminal domain RD3 PF14473.6 EGR28180.1 - 0.01 15.7 0.7 0.01 15.7 0.7 2.0 2 0 0 2 2 2 0 RD3 protein ApoLp-III PF07464.11 EGR28180.1 - 0.048 13.8 12.9 0.2 11.8 1.1 2.8 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Orf78 PF06024.12 EGR28180.1 - 0.27 11.5 3.3 0.18 12.1 0.7 2.1 2 0 0 2 2 2 0 Orf78 (ac78) zf-B_box PF00643.24 EGR28180.1 - 0.32 11.2 7.5 0.7 10.1 7.5 1.6 1 0 0 1 1 1 0 B-box zinc finger Noelin-1 PF12308.8 EGR28180.1 - 1.4 8.9 4.9 1.2 9.1 0.7 2.6 2 0 0 2 2 2 0 Neurogenesis glycoprotein HP0268 PF18618.1 EGR28180.1 - 1.6 9.2 10.0 0.82 10.1 3.7 3.5 3 0 0 3 3 3 0 HP0268 VPS13_C PF16909.5 EGR28181.1 - 5.7e-45 153.3 10.6 2e-42 145.0 4.9 4.7 3 1 1 4 4 4 2 Vacuolar-sorting-associated 13 protein C-terminal ABC2_membrane_2 PF12679.7 EGR28181.1 - 0.34 10.1 0.0 0.34 10.1 0.0 3.4 1 1 2 3 3 3 0 ABC-2 family transporter protein VPS13 PF16908.5 EGR28183.1 - 1.5e-26 93.6 7.4 1.5e-26 93.6 7.4 2.5 1 1 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 EGR28183.1 - 1.8e-05 24.8 5.1 8.8e-05 22.6 4.0 2.9 2 1 0 2 2 2 1 N-terminal region of Chorein or VPS13 Septin PF00735.18 EGR28184.1 - 6.3e-24 84.7 8.4 2.6e-14 53.2 2.5 2.2 2 0 0 2 2 2 2 Septin AIG1 PF04548.16 EGR28184.1 - 1.7e-06 27.6 2.5 7.9e-05 22.1 0.2 2.4 1 1 0 2 2 2 2 AIG1 family MMR_HSR1 PF01926.23 EGR28184.1 - 2.1e-05 24.6 0.2 5.1e-05 23.3 0.2 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGR28184.1 - 7e-05 22.5 1.0 0.64 9.5 0.0 3.2 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Ras PF00071.22 EGR28184.1 - 0.00012 21.8 0.1 0.00029 20.5 0.1 1.7 1 0 0 1 1 1 1 Ras family Dynamin_N PF00350.23 EGR28184.1 - 0.00012 22.2 1.2 0.038 14.0 0.0 3.0 2 1 1 3 3 3 2 Dynamin family Roc PF08477.13 EGR28184.1 - 0.0002 21.5 0.2 0.00078 19.7 0.2 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EGR28184.1 - 0.012 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family TniB PF05621.11 EGR28184.1 - 0.015 14.8 0.3 0.036 13.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 EGR28184.1 - 0.021 14.9 0.5 0.021 14.9 0.5 2.3 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGR28184.1 - 0.026 14.3 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain XPA_N PF01286.18 EGR28184.1 - 0.093 12.8 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 XPA protein N-terminal TPR_12 PF13424.6 EGR28186.1 - 4.2e-28 97.4 3.2 6.9e-12 45.5 0.1 4.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGR28186.1 - 4e-21 74.2 4.2 3.7e-06 26.6 0.0 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGR28186.1 - 5.6e-20 69.8 17.5 4.2e-05 23.4 0.0 6.9 6 0 0 6 6 6 4 Tetratricopeptide repeat Pkinase PF00069.25 EGR28186.1 - 2e-19 70.0 3.5 4.3e-19 68.9 3.5 1.5 1 0 0 1 1 1 1 Protein kinase domain TPR_1 PF00515.28 EGR28186.1 - 4.9e-19 67.3 18.1 8.5e-05 22.2 0.1 7.2 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGR28186.1 - 3e-18 64.4 14.2 0.00012 21.9 0.1 6.6 5 1 0 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.6 EGR28186.1 - 3.2e-14 51.8 4.6 0.00035 20.4 0.0 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EGR28186.1 - 8.9e-09 35.2 0.0 0.00031 20.3 0.0 2.1 1 1 1 2 2 2 2 MalT-like TPR region Pkinase_Tyr PF07714.17 EGR28186.1 - 2.8e-06 26.8 0.5 6.4e-06 25.6 0.5 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase TPR_11 PF13414.6 EGR28186.1 - 2.4e-05 23.9 8.2 0.87 9.3 0.0 5.7 5 1 1 6 6 6 3 TPR repeat SHNi-TPR PF10516.9 EGR28186.1 - 0.00035 20.0 0.6 0.0019 17.6 0.2 2.6 2 0 0 2 2 2 1 SHNi-TPR TPR_14 PF13428.6 EGR28186.1 - 0.0014 19.3 0.0 3.7 8.6 0.0 4.3 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGR28186.1 - 0.0022 18.6 0.2 3.2 8.5 0.0 3.5 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGR28186.1 - 0.026 15.1 0.0 23 5.9 0.0 4.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGR28186.1 - 0.44 11.0 8.4 18 6.0 0.4 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PALP PF00291.25 EGR28187.1 - 2e-61 208.0 0.0 2.4e-61 207.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PIG-H PF10181.9 EGR28191.1 - 0.021 14.7 0.8 0.023 14.6 0.8 1.2 1 0 0 1 1 1 0 GPI-GlcNAc transferase complex, PIG-H component DUF667 PF05018.13 EGR28193.1 - 8.1e-09 35.5 3.8 8.7e-09 35.4 3.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF667) EF-hand_1 PF00036.32 EGR28194.1 - 0.013 15.0 0.2 0.024 14.1 0.2 1.5 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 EGR28194.1 - 0.05 14.1 0.0 0.076 13.5 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 EGR28194.1 - 0.067 13.2 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain Caleosin PF05042.13 EGR28194.1 - 0.067 13.1 0.1 0.072 13.0 0.1 1.1 1 0 0 1 1 1 0 Caleosin related protein Pkinase PF00069.25 EGR28195.1 - 2.5e-61 207.4 0.2 3.4e-61 206.9 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28195.1 - 1.2e-28 100.1 0.1 1.8e-28 99.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28195.1 - 1.6e-05 24.4 0.1 0.099 11.9 0.0 2.3 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 EGR28195.1 - 0.015 14.7 0.1 0.042 13.2 0.1 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC_tran PF00005.27 EGR28196.1 - 7.7e-47 159.2 7.7 1.4e-27 96.9 0.3 3.4 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 EGR28196.1 - 9e-09 35.4 9.3 1.7e-08 34.5 9.3 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_7 PF12775.7 EGR28196.1 - 2.2e-06 27.3 0.2 0.058 12.9 0.0 3.4 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_22 PF13401.6 EGR28196.1 - 1.5e-05 25.3 0.0 0.05 13.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGR28196.1 - 3.2e-05 23.6 0.0 0.19 11.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EGR28196.1 - 3.3e-05 23.4 28.6 0.0076 15.7 3.1 5.0 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGR28196.1 - 3.7e-05 23.7 3.8 0.014 15.3 0.1 3.2 4 0 0 4 4 3 2 RsgA GTPase AAA_16 PF13191.6 EGR28196.1 - 0.0001 22.7 0.0 0.68 10.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain T2SSE PF00437.20 EGR28196.1 - 0.00021 20.4 0.0 0.56 9.2 0.0 2.7 2 0 0 2 2 2 2 Type II/IV secretion system protein NTPase_1 PF03266.15 EGR28196.1 - 0.00023 21.1 0.6 0.47 10.4 0.2 3.7 3 0 0 3 3 3 1 NTPase RNA_helicase PF00910.22 EGR28196.1 - 0.00032 21.1 2.1 1.3 9.5 0.0 4.6 4 0 0 4 4 4 1 RNA helicase MMR_HSR1 PF01926.23 EGR28196.1 - 0.00066 19.7 0.1 0.84 9.7 0.0 3.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase DEAD PF00270.29 EGR28196.1 - 0.0015 18.3 0.7 0.071 12.9 0.0 3.4 3 1 0 3 3 3 1 DEAD/DEAH box helicase NACHT PF05729.12 EGR28196.1 - 0.0035 17.3 0.0 0.087 12.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain TsaE PF02367.17 EGR28196.1 - 0.0039 17.2 0.0 0.87 9.6 0.0 2.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE KAP_NTPase PF07693.14 EGR28196.1 - 0.0079 15.5 0.1 0.0079 15.5 0.1 3.4 3 1 1 4 4 4 1 KAP family P-loop domain cobW PF02492.19 EGR28196.1 - 0.0081 15.8 0.0 0.43 10.2 0.0 2.7 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.26 EGR28196.1 - 0.0094 15.7 0.1 2.6 7.7 0.0 3.2 3 0 0 3 3 3 1 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 EGR28196.1 - 0.01 15.2 0.0 2.4 7.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family Roc PF08477.13 EGR28196.1 - 0.011 15.9 0.0 2.8 8.2 0.0 3.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 EGR28196.1 - 0.028 13.7 0.0 6.3 6.0 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_33 PF13671.6 EGR28196.1 - 0.045 13.9 0.0 16 5.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EGR28196.1 - 0.058 12.8 0.0 0.5 9.7 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATP-synt_ab PF00006.25 EGR28196.1 - 0.069 12.8 0.3 16 5.0 0.0 3.3 4 0 0 4 4 4 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA PF00004.29 EGR28196.1 - 0.071 13.5 7.3 5.4 7.5 0.2 4.2 4 2 1 5 5 4 0 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 EGR28196.1 - 0.089 13.0 0.0 18 5.7 0.0 3.4 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.6 EGR28196.1 - 0.21 12.2 7.9 5.6 7.5 0.8 4.3 4 1 0 4 4 4 0 AAA domain SRPRB PF09439.10 EGR28196.1 - 0.35 10.3 7.9 0.69 9.3 0.0 3.6 3 1 1 4 4 4 0 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 EGR28196.1 - 0.71 9.9 14.2 4.2 7.4 0.0 5.1 4 1 0 4 4 4 0 Dynamin family CDC50 PF03381.15 EGR28198.1 - 7.8e-60 202.8 11.0 9.9e-60 202.4 11.0 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Plus-3 PF03126.18 EGR28198.1 - 0.074 13.6 1.6 0.087 13.3 0.2 1.9 2 0 0 2 2 2 0 Plus-3 domain Lipoprotein_2 PF00921.17 EGR28199.1 - 0.13 11.8 7.2 0.18 11.3 7.2 1.2 1 0 0 1 1 1 0 Borrelia lipoprotein PIN_5 PF08745.11 EGR28199.1 - 0.75 9.2 5.4 1.1 8.7 5.4 1.2 1 0 0 1 1 1 0 PINc domain ribonuclease Helicase_C PF00271.31 EGR28200.1 - 5.5e-20 71.8 0.7 8.2e-19 68.0 0.2 3.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SLIDE PF09111.10 EGR28200.1 - 7.8e-05 22.7 0.3 7.8e-05 22.7 0.3 5.4 4 2 2 6 6 6 1 SLIDE MIIP PF15734.5 EGR28200.1 - 8.6 5.7 17.5 16 4.9 17.5 1.3 1 0 0 1 1 1 0 Migration and invasion-inhibitory Pkinase PF00069.25 EGR28201.1 - 1.6e-34 119.5 10.7 2.3e-34 119.0 10.7 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28201.1 - 1.3e-23 83.7 6.2 2.3e-23 82.8 6.2 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR28201.1 - 0.00058 18.8 1.0 0.00074 18.4 0.0 1.7 2 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGR28201.1 - 0.0017 18.3 0.0 0.0023 17.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase PF00069.25 EGR28202.1 - 1.3e-76 257.4 2.2 1.3e-76 257.4 2.2 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28202.1 - 2.4e-48 164.7 0.5 2.4e-48 164.7 0.5 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28202.1 - 7e-07 28.9 0.0 7e-07 28.9 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 EGR28202.1 - 1e-06 27.9 3.1 2.3e-06 26.6 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGR28202.1 - 0.00028 20.3 0.3 0.00028 20.3 0.3 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF_assoc_2 PF08356.12 EGR28202.1 - 0.0048 16.9 3.6 0.018 15.0 3.6 2.0 1 0 0 1 1 1 1 EF hand associated APH PF01636.23 EGR28202.1 - 0.044 13.7 0.0 0.16 11.9 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family CxC6 PF18721.1 EGR28202.1 - 0.32 11.3 0.1 0.32 11.3 0.1 2.4 2 1 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases BPL_N PF09825.9 EGR28202.1 - 4.4 6.3 7.6 8.1 5.4 7.6 1.4 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal Guanylate_cyc PF00211.20 EGR28203.1 - 4.3e-79 264.4 10.8 1.4e-43 148.6 2.2 2.8 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain PhoLip_ATPase_C PF16212.5 EGR28204.1 - 2.3e-54 184.8 33.5 2.3e-54 184.8 33.5 2.5 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGR28204.1 - 1.2e-18 66.6 0.5 1.2e-18 66.6 0.5 3.6 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGR28204.1 - 8.1e-11 42.6 0.2 0.00012 22.4 0.1 3.5 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGR28204.1 - 3.5e-10 39.8 0.8 1.3e-08 34.8 0.2 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGR28204.1 - 2.2e-09 37.1 0.0 9.1e-08 31.8 0.0 2.4 1 1 0 2 2 2 1 E1-E2 ATPase Ribosomal_S24e PF01282.19 EGR28205.1 - 6.6e-28 96.5 0.1 1e-27 95.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e TPR_8 PF13181.6 EGR28206.1 - 1e-18 65.9 3.8 0.00075 19.5 0.1 4.9 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGR28206.1 - 2.9e-18 64.8 2.5 5.7e-07 29.1 0.2 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGR28206.1 - 9.7e-18 62.8 0.1 9.5e-06 25.4 0.1 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGR28206.1 - 1.2e-12 47.9 0.1 0.0029 17.9 0.2 3.3 2 1 0 3 3 3 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGR28206.1 - 8.4e-12 44.2 0.2 0.0003 20.6 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGR28206.1 - 1.3e-09 37.6 0.0 0.28 11.1 0.3 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGR28206.1 - 8.7e-07 28.9 1.8 0.014 15.8 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 EGR28206.1 - 0.00033 20.9 0.2 1.7 9.0 0.0 3.5 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGR28206.1 - 0.005 17.5 0.0 0.52 11.0 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGR28206.1 - 0.01 15.5 8.3 0.21 11.3 1.0 4.3 3 2 2 5 5 5 0 TPR repeat TPR_19 PF14559.6 EGR28206.1 - 0.071 13.6 0.6 15 6.2 0.2 3.0 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGR28206.1 - 0.19 12.6 0.0 17 6.6 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 EGR28207.1 - 3.2e-17 62.4 0.6 6.5e-17 61.4 0.6 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGR28207.1 - 1.5e-09 38.0 3.7 6.7e-09 35.9 3.7 2.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGR28207.1 - 0.00018 21.3 4.7 0.00018 21.3 4.7 2.4 2 1 0 2 2 2 1 Myb DNA-binding like HEPN_Swt1 PF18731.1 EGR28207.1 - 0.48 10.8 8.9 0.14 12.5 5.1 2.0 2 0 0 2 2 2 0 Swt1-like HEPN Pkinase PF00069.25 EGR28208.1 - 2.9e-44 151.4 0.2 2.9e-44 151.4 0.2 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28208.1 - 1.3e-28 100.0 0.0 1.3e-28 100.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28208.1 - 1.6e-08 34.2 0.7 2.1e-08 33.8 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGR28208.1 - 0.044 13.1 0.1 0.083 12.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tudor-knot PF11717.8 EGR28209.1 - 1.5e-06 28.0 1.1 1.5e-06 28.0 1.1 2.6 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain DUF881 PF05949.12 EGR28209.1 - 0.018 14.9 1.1 0.056 13.3 0.5 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF881) MBT PF02820.18 EGR28209.1 - 0.046 14.1 0.2 0.24 11.7 0.1 2.2 2 0 0 2 2 2 0 mbt repeat PMC2NT PF08066.12 EGR28209.1 - 0.41 11.4 4.4 1.9 9.2 0.0 3.2 2 1 1 3 3 3 0 PMC2NT (NUC016) domain Citrate_synt PF00285.21 EGR28210.1 - 1.3e-132 442.3 0.0 1.6e-132 442.0 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain KIAA1430 PF13879.6 EGR28211.1 - 6.1 7.7 16.9 2.2 9.1 4.0 2.5 1 1 1 2 2 2 0 KIAA1430 homologue Dynamin_M PF01031.20 EGR28212.1 - 1.4e-92 310.0 2.5 1.4e-92 310.0 2.5 1.9 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 EGR28212.1 - 1e-46 159.0 0.1 2.1e-46 158.0 0.1 1.6 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 EGR28212.1 - 6.7e-26 90.3 1.6 6.7e-26 90.3 1.6 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGR28212.1 - 6.1e-06 26.3 0.0 1.6e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF1186 PF06685.11 EGR28212.1 - 0.063 12.7 3.4 0.04 13.3 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1186) HECT PF00632.25 EGR28213.1 - 4.6e-88 295.6 5.0 4.6e-88 295.6 5.0 1.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) NID PF07292.13 EGR28213.1 - 0.0021 18.7 0.2 0.0064 17.1 0.2 1.8 1 0 0 1 1 1 1 Nmi/IFP 35 domain (NID) CDC45 PF02724.14 EGR28215.1 - 0.0065 14.8 23.3 0.0081 14.5 23.3 1.2 1 0 0 1 1 1 1 CDC45-like protein LAP1C PF05609.12 EGR28215.1 - 4.4 6.3 22.1 4.8 6.1 22.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) BUD22 PF09073.10 EGR28215.1 - 5.6 6.2 29.5 6.9 5.9 29.5 1.1 1 0 0 1 1 1 0 BUD22 YajC PF02699.15 EGR28217.1 - 6.4 6.7 9.9 0.67 9.9 3.9 2.4 2 0 0 2 2 2 0 Preprotein translocase subunit Fer2 PF00111.27 EGR28218.1 - 0.0042 17.0 0.0 0.0064 16.4 0.0 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain PSI PF01437.25 EGR28219.1 - 1.9e-07 31.5 43.8 2e-05 25.0 12.7 3.6 3 0 0 3 3 3 2 Plexin repeat Collagen PF01391.18 EGR28219.1 - 0.0045 16.7 9.4 0.0077 16.0 9.4 1.2 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Peptidase_M41 PF01434.18 EGR28220.1 - 1.1e-51 175.5 0.3 1.1e-51 175.5 0.3 1.9 2 0 0 2 2 1 1 Peptidase family M41 AAA PF00004.29 EGR28220.1 - 6.6e-43 146.3 1.9 2.5e-42 144.4 0.0 2.9 4 0 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) RHD3 PF05879.12 EGR28220.1 - 2e-41 142.0 5.5 2e-41 142.0 5.5 1.5 1 1 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 EGR28220.1 - 5.3e-10 39.4 2.3 3.1e-07 30.4 0.5 3.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_lid_3 PF17862.1 EGR28220.1 - 8.5e-08 31.9 0.0 2.6e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGR28220.1 - 1.2e-07 32.3 0.1 0.0073 16.7 0.1 3.4 2 1 1 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 EGR28220.1 - 1.6e-06 28.2 0.3 1.7e-05 24.9 0.0 3.0 4 0 0 4 4 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGR28220.1 - 8.8e-06 26.0 2.5 0.054 13.8 0.1 4.1 4 0 0 4 4 3 1 AAA domain AAA_2 PF07724.14 EGR28220.1 - 8.9e-06 25.9 0.2 0.0001 22.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 EGR28220.1 - 1.7e-05 24.9 10.3 0.0089 16.1 0.0 4.6 4 1 1 5 5 5 2 AAA domain GBP PF02263.19 EGR28220.1 - 4.8e-05 22.8 0.2 0.00011 21.5 0.2 1.6 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain AAA_33 PF13671.6 EGR28220.1 - 0.00013 22.2 1.4 0.053 13.7 0.0 3.2 4 0 0 4 4 3 1 AAA domain FeoB_N PF02421.18 EGR28220.1 - 0.00013 21.5 0.5 0.054 13.0 0.1 2.7 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_28 PF13521.6 EGR28220.1 - 0.00027 21.2 0.2 0.38 11.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain ABC_tran PF00005.27 EGR28220.1 - 0.00041 20.9 0.6 1.5 9.3 0.1 3.2 2 0 0 2 2 2 2 ABC transporter Zeta_toxin PF06414.12 EGR28220.1 - 0.00058 19.2 0.0 0.0044 16.3 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin AAA_29 PF13555.6 EGR28220.1 - 0.001 18.7 0.4 0.56 10.0 0.0 3.0 3 0 0 3 3 2 1 P-loop containing region of AAA domain Roc PF08477.13 EGR28220.1 - 0.0017 18.6 7.7 0.096 12.9 0.2 3.9 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 EGR28220.1 - 0.002 18.7 2.9 0.096 13.2 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_25 PF13481.6 EGR28220.1 - 0.002 17.7 0.9 1.1 8.8 0.2 3.3 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EGR28220.1 - 0.0063 16.3 0.6 0.029 14.1 0.0 2.4 3 0 0 3 3 3 1 IstB-like ATP binding protein RuvB_N PF05496.12 EGR28220.1 - 0.0091 15.8 0.0 0.03 14.1 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 EGR28220.1 - 0.013 15.4 0.7 0.36 10.7 0.0 2.9 3 0 0 3 3 2 0 NACHT domain ATPase PF06745.13 EGR28220.1 - 0.017 14.5 13.6 0.43 9.9 0.0 4.8 5 0 0 5 5 5 0 KaiC RNA_helicase PF00910.22 EGR28220.1 - 0.019 15.3 4.6 2.2 8.7 0.0 3.5 3 0 0 3 3 3 0 RNA helicase RsgA_GTPase PF03193.16 EGR28220.1 - 0.02 14.8 0.2 4 7.3 0.1 3.1 2 0 0 2 2 2 0 RsgA GTPase Mg_chelatase PF01078.21 EGR28220.1 - 0.021 14.2 0.2 0.11 11.9 0.2 2.0 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EGR28220.1 - 0.073 13.1 0.0 0.26 11.3 0.0 1.9 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 EGR28220.1 - 0.077 13.0 12.6 0.062 13.4 7.4 3.6 3 1 0 3 3 3 0 Dynamin family Ploopntkinase3 PF18751.1 EGR28220.1 - 0.12 12.3 0.1 16 5.4 0.0 2.9 3 0 0 3 3 3 0 P-loop Nucleotide Kinase3 AAA_24 PF13479.6 EGR28220.1 - 0.14 11.9 4.9 1.1 9.0 0.0 3.9 5 0 0 5 5 5 0 AAA domain GTP_EFTU PF00009.27 EGR28220.1 - 2.1 7.8 5.3 2.2 7.8 0.0 3.1 4 0 0 4 4 3 0 Elongation factor Tu GTP binding domain MORN PF02493.20 EGR28221.1 - 4e-30 101.9 92.4 1.8e-05 24.3 3.2 15.6 17 0 0 17 17 17 10 MORN repeat MeaB PF03308.16 EGR28221.1 - 0.045 12.7 0.5 0.066 12.2 0.5 1.1 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Yip1 PF04893.17 EGR28222.1 - 1.2e-15 57.7 14.7 1.7e-15 57.2 14.7 1.3 1 0 0 1 1 1 1 Yip1 domain DUF1282 PF06930.12 EGR28222.1 - 0.024 14.4 10.7 0.036 13.8 10.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1282) Syja_N PF02383.18 EGR28223.1 - 7.2e-73 245.7 8.8 7.2e-73 245.7 8.8 1.7 2 0 0 2 2 2 1 SacI homology domain Ras PF00071.22 EGR28223.1 - 2.1e-37 128.2 0.1 6.2e-37 126.7 0.0 1.9 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EGR28223.1 - 2.8e-26 92.1 0.2 3.7e-25 88.5 0.0 2.9 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR28223.1 - 1.4e-11 44.2 0.2 5.8e-11 42.1 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR28223.1 - 0.00011 22.2 0.0 0.0007 19.7 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGR28223.1 - 0.00018 21.1 0.0 0.002 17.7 0.0 2.6 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGR28223.1 - 0.00089 18.7 0.4 0.013 14.9 0.0 2.5 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region bPH_1 PF08000.11 EGR28224.1 - 0.04 14.0 0.2 0.048 13.8 0.2 1.3 1 1 0 1 1 1 0 Bacterial PH domain Abhydrolase_3 PF07859.13 EGR28225.1 - 1.3e-43 149.3 0.0 2.1e-43 148.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGR28225.1 - 2.2e-12 46.5 1.0 3e-12 46.1 1.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 EGR28225.1 - 0.00026 20.0 1.3 0.002 17.1 1.1 2.1 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EGR28225.1 - 0.091 12.2 0.0 21 4.5 0.0 2.7 3 0 0 3 3 3 0 Prolyl oligopeptidase family Pkinase PF00069.25 EGR28226.1 - 4.9e-45 153.9 2.6 4.9e-45 153.9 2.6 3.1 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28226.1 - 6.3e-22 78.1 0.0 4.1e-21 75.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGR28227.1 - 3.6e-69 233.0 0.1 4.6e-69 232.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28227.1 - 6.2e-40 137.1 0.0 8.1e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR28227.1 - 0.0027 17.1 0.1 0.0041 16.5 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR28227.1 - 0.012 14.4 0.0 0.018 13.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 EGR28227.1 - 0.043 13.4 0.1 0.075 12.6 0.1 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RRM_1 PF00076.22 EGR28228.1 - 1.5e-15 56.8 0.1 3.1e-15 55.8 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EGR28228.1 - 6.2e-07 29.3 0.9 1.4e-06 28.1 0.9 1.7 1 0 0 1 1 1 1 Zinc finger domain RRM_occluded PF16842.5 EGR28228.1 - 2.5e-06 27.2 0.0 4.8e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH PF00642.24 EGR28228.1 - 4.8e-05 23.2 0.3 4.8e-05 23.2 0.3 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_5 PF13893.6 EGR28228.1 - 7.4e-05 22.3 0.0 0.00013 21.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4523 PF15023.6 EGR28228.1 - 0.00011 22.0 0.0 0.0002 21.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) Torus PF16131.5 EGR28228.1 - 0.00013 22.6 0.3 0.00035 21.2 0.0 2.0 2 0 0 2 2 2 1 Torus domain RRM_3 PF08777.11 EGR28228.1 - 0.0084 16.1 0.2 0.02 14.9 0.0 1.7 2 0 0 2 2 2 1 RNA binding motif zf-CCCH_3 PF15663.5 EGR28228.1 - 0.032 14.4 2.3 0.053 13.7 0.1 2.2 2 0 0 2 2 2 0 Zinc-finger containing family zf-CCCH_4 PF18044.1 EGR28228.1 - 0.15 11.9 0.2 0.28 11.0 0.2 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EGR28228.1 - 0.21 12.1 2.1 0.34 11.5 0.4 2.2 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Pyridoxal_deC PF00282.19 EGR28229.1 - 3.7e-36 124.7 0.0 6.2e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain MORN PF02493.20 EGR28229.1 - 1.8e-05 24.4 15.2 0.21 11.6 0.1 6.0 6 1 0 6 6 6 3 MORN repeat DUF1694 PF07997.11 EGR28231.1 - 0.71 10.0 10.3 0.45 10.6 8.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1694) Mrx7 PF10906.8 EGR28231.1 - 6.5 7.1 11.2 11 6.4 1.9 2.4 1 1 1 2 2 2 0 MIOREX complex component 7 DUF3683 PF12447.8 EGR28232.1 - 0.016 15.3 1.3 0.14 12.3 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3683) DUF3010 PF11215.8 EGR28232.1 - 3.3 8.0 9.0 0.42 10.9 3.4 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3010) COX5A PF02284.16 EGR28232.1 - 6.3 6.9 10.3 2.3 8.3 0.3 3.1 2 1 1 3 3 3 0 Cytochrome c oxidase subunit Va Vps52 PF04129.12 EGR28233.1 - 5e-70 236.7 36.1 9.3e-70 235.8 36.1 1.4 1 0 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 EGR28233.1 - 1.4e-12 46.8 25.6 1.4e-12 46.8 25.6 2.3 1 1 1 2 2 2 1 Exocyst complex component Sec3 Colicin-DNase PF12639.7 EGR28233.1 - 1.5 9.7 7.1 4 8.3 0.2 3.6 3 0 0 3 3 3 0 DNase/tRNase domain of colicin-like bacteriocin Cep57_MT_bd PF06657.13 EGR28233.1 - 7.3 7.1 9.1 1.7 9.1 0.7 3.9 4 1 0 4 4 4 0 Centrosome microtubule-binding domain of Cep57 Peptidase_M16 PF00675.20 EGR28234.1 - 7.5e-33 113.6 0.0 7.5e-33 113.6 0.0 4.5 4 1 1 5 5 5 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 EGR28234.1 - 3.5e-28 98.7 27.4 3.5e-28 98.7 27.4 3.9 3 1 0 3 3 3 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 EGR28234.1 - 2.2e-09 37.6 22.1 4.5e-08 33.3 4.5 3.9 3 0 0 3 3 3 3 Peptidase M16 inactive domain Alpha-amylase PF00128.24 EGR28235.1 - 5.2e-11 42.7 1.7 2.2e-07 30.8 0.4 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 EGR28235.1 - 5.4e-09 36.3 0.5 1.7e-08 34.7 0.0 2.0 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) AMPK1_CBM PF16561.5 EGR28235.1 - 0.0052 17.0 0.0 0.017 15.3 0.0 1.9 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Alpha-amylase_C PF02806.18 EGR28235.1 - 0.025 15.0 0.1 0.27 11.7 0.0 2.5 2 0 0 2 2 2 0 Alpha amylase, C-terminal all-beta domain GST_C_6 PF17171.4 EGR28235.1 - 0.045 13.5 0.0 0.14 12.0 0.0 1.8 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain RP853 PF17542.2 EGR28235.1 - 9.1 5.3 9.0 0.1 11.7 1.1 1.6 2 0 0 2 2 2 0 Uncharacterized RP853 CIA30 PF08547.12 EGR28236.1 - 1e-15 58.1 0.0 1.8e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 EGR28236.1 - 0.0093 15.9 0.0 0.019 14.9 0.0 1.5 1 1 0 1 1 1 1 Surface glycan-binding protein B xyloglucan binding domain DUF1494 PF07379.11 EGR28236.1 - 0.03 14.2 2.5 0.19 11.6 0.1 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1494) DUF5590 PF17881.1 EGR28236.1 - 0.043 13.9 0.7 3.5 7.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF5590) MORN PF02493.20 EGR28237.1 - 1.3e-59 194.7 78.3 1.6e-08 34.0 1.4 10.7 11 0 0 11 11 11 10 MORN repeat Cellulose_synt PF03552.14 EGR28237.1 - 0.4 9.1 5.9 0.51 8.8 5.9 1.1 1 0 0 1 1 1 0 Cellulose synthase CC2D2AN-C2 PF15625.6 EGR28239.1 - 3.3e-16 59.5 0.4 1.2e-15 57.6 0.4 2.0 1 0 0 1 1 1 1 CC2D2A N-terminal C2 domain DnaJ PF00226.31 EGR28240.1 - 7.1e-22 77.3 2.4 7.1e-22 77.3 2.4 2.0 2 0 0 2 2 2 1 DnaJ domain DnaJ_C PF01556.18 EGR28240.1 - 1.5e-11 44.6 1.6 2.2e-11 44.0 1.6 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EGR28240.1 - 1.8e-08 34.6 16.2 4.7e-08 33.3 16.2 1.8 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGR28240.1 - 0.16 12.0 9.6 0.37 10.8 1.4 2.4 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Elf-1_N PF12310.8 EGR28241.1 - 0.11 13.1 0.2 0.16 12.5 0.2 1.2 1 0 0 1 1 1 0 Transcription factor protein N terminal OSCP PF00213.18 EGR28242.1 - 9.4e-38 130.0 3.8 1.2e-37 129.7 3.8 1.1 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit Flot PF15975.5 EGR28242.1 - 0.0068 16.6 0.1 0.014 15.6 0.1 1.5 1 0 0 1 1 1 1 Flotillin Baculo_RING PF05883.11 EGR28243.1 - 0.0054 16.7 0.3 0.013 15.5 0.3 1.6 1 0 0 1 1 1 1 Baculovirus U-box/Ring-like domain Flavi_capsid PF01003.19 EGR28243.1 - 0.09 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Flavivirus capsid protein C DUF3488 PF11992.8 EGR28244.1 - 2.4 7.0 8.6 3.3 6.6 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Lipase_3 PF01764.25 EGR28245.1 - 5.4e-28 97.7 0.0 8.2e-28 97.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 EGR28245.1 - 1.6e-06 27.6 0.0 2.3e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Cutinase PF01083.22 EGR28245.1 - 9.2e-05 22.5 0.0 0.00015 21.8 0.0 1.3 1 1 0 1 1 1 1 Cutinase DUF915 PF06028.11 EGR28245.1 - 0.00075 18.9 0.0 0.0011 18.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) LCAT PF02450.15 EGR28245.1 - 0.0024 17.1 0.0 0.003 16.8 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF676 PF05057.14 EGR28245.1 - 0.0031 17.1 0.0 0.0033 16.9 0.0 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF3089 PF11288.8 EGR28245.1 - 0.015 14.9 0.1 3.2 7.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) PGAP1 PF07819.13 EGR28245.1 - 0.028 14.1 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 EGR28245.1 - 0.071 12.7 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGR28245.1 - 0.076 13.6 0.0 0.092 13.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EGR28245.1 - 0.084 12.7 0.0 0.1 12.4 0.0 1.1 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF2974 PF11187.8 EGR28245.1 - 0.12 11.9 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 EGR28245.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF4810 PF16068.5 EGR28245.1 - 0.22 12.1 0.0 0.22 12.1 0.0 1.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4810) RRM_1 PF00076.22 EGR28246.1 - 3e-33 113.4 9.9 3.4e-14 52.4 0.4 4.0 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGR28246.1 - 0.00087 19.4 0.4 0.43 10.7 0.1 4.6 4 2 0 4 4 4 1 RNA recognition motif Phage_TAC_13 PF16459.5 EGR28246.1 - 0.0076 16.7 5.3 4.1 7.9 1.1 3.9 3 0 0 3 3 3 2 Phage tail assembly chaperone, TAC Limkain-b1 PF11608.8 EGR28246.1 - 0.014 15.4 0.0 0.07 13.2 0.0 2.3 1 0 0 1 1 1 0 Limkain b1 7TM_GPCR_Srh PF10318.9 EGR28246.1 - 0.25 10.3 11.1 0.74 8.8 11.1 1.8 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srh CH_2 PF06294.11 EGR28247.1 - 3.5e-29 100.8 9.4 1.1e-22 79.9 0.2 3.3 2 2 1 3 3 3 2 CH-like domain in sperm protein CAMSAP_CH PF11971.8 EGR28247.1 - 9.4e-14 51.0 0.3 4.7e-13 48.8 0.2 2.1 1 1 1 2 2 2 1 CAMSAP CH domain CH PF00307.31 EGR28247.1 - 0.01 16.0 0.3 0.01 16.0 0.3 2.6 1 1 1 2 2 2 0 Calponin homology (CH) domain DUF2316 PF10078.9 EGR28247.1 - 0.2 11.9 4.7 3 8.1 1.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) UPF0552 PF10574.9 EGR28247.1 - 0.22 10.8 7.2 0.31 10.4 7.2 1.3 1 0 0 1 1 1 0 Arp2/3-interacting proteins Arpin SCAPER_N PF16501.5 EGR28247.1 - 0.34 11.0 6.3 0.061 13.3 2.1 2.0 2 1 1 3 3 3 0 S phase cyclin A-associated protein in the endoplasmic reticulum ACT_5 PF13710.6 EGR28247.1 - 0.56 10.1 5.9 4.4 7.2 0.0 4.1 3 1 2 5 5 5 0 ACT domain DUF641 PF04859.12 EGR28247.1 - 2.8 8.3 13.8 10 6.5 13.3 2.0 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) ANAPC_CDC26 PF10471.9 EGR28247.1 - 3 8.7 11.9 6 7.8 11.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Kinesin PF00225.23 EGR28248.1 - 4.9e-17 61.9 2.5 5.7e-17 61.6 2.5 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR28248.1 - 8.1e-13 48.6 1.3 1e-12 48.2 1.3 1.2 1 0 0 1 1 1 1 Microtubule binding RNA_helicase PF00910.22 EGR28248.1 - 0.025 15.0 1.7 0.11 12.9 0.4 2.2 2 0 0 2 2 2 0 RNA helicase T2SSE PF00437.20 EGR28248.1 - 0.083 11.9 0.0 0.083 11.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 EGR28248.1 - 0.14 12.5 0.0 0.19 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 EGR28248.1 - 1.7 8.6 7.5 0.45 10.5 0.4 2.8 1 1 2 3 3 3 0 Type III restriction enzyme, res subunit Ras PF00071.22 EGR28249.1 - 4.6e-49 166.1 0.5 7e-49 165.5 0.5 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR28249.1 - 8e-37 126.1 0.1 8e-37 126.1 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR28249.1 - 3.2e-20 72.3 0.1 4.3e-20 71.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGR28249.1 - 3.6e-11 42.9 0.4 5.3e-11 42.3 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGR28249.1 - 1.3e-08 34.9 0.1 2.6e-08 33.9 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGR28249.1 - 2.2e-07 30.9 0.1 0.00034 20.6 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGR28249.1 - 0.00012 21.7 0.2 0.00087 18.9 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGR28249.1 - 0.00037 20.0 0.6 0.00071 19.1 0.6 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 EGR28249.1 - 0.0024 18.0 6.4 0.023 14.8 1.6 3.3 1 1 0 2 2 2 1 Dynamin family TniB PF05621.11 EGR28249.1 - 0.014 14.8 0.1 0.33 10.4 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein FeoB_N PF02421.18 EGR28249.1 - 0.014 14.9 0.2 0.072 12.6 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B FtsK_alpha PF17854.1 EGR28249.1 - 0.097 12.8 0.4 1 9.5 0.2 2.4 2 1 0 2 2 2 0 FtsK alpha domain Aldo_ket_red PF00248.21 EGR28250.1 - 7.5e-17 61.5 0.0 3.6e-16 59.2 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family SF-assemblin PF06705.11 EGR28251.1 - 2.4e-10 40.2 43.1 6.5e-10 38.8 36.4 2.9 1 1 1 2 2 2 2 SF-assemblin/beta giardin ApoO PF09769.9 EGR28251.1 - 0.00038 20.4 3.8 0.22 11.5 0.2 2.9 3 0 0 3 3 3 2 Apolipoprotein O CdvA PF18822.1 EGR28251.1 - 0.042 13.7 1.8 0.042 13.7 1.8 4.6 2 2 3 5 5 5 0 CdvA-like coiled-coil domain SCO1-SenC PF02630.14 EGR28251.1 - 0.16 11.9 1.9 0.19 11.6 0.5 1.9 2 1 0 2 2 2 0 SCO1/SenC Cob_adeno_trans PF01923.18 EGR28251.1 - 1.2 9.2 14.8 0.063 13.4 2.0 2.9 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Fzo_mitofusin PF04799.13 EGR28251.1 - 1.3 8.5 19.4 0.03 13.9 3.6 3.1 2 1 1 3 3 3 0 fzo-like conserved region YtxH PF12732.7 EGR28251.1 - 1.8 9.1 13.7 3.5e+02 1.8 13.7 3.5 1 1 0 1 1 1 0 YtxH-like protein betaPIX_CC PF16523.5 EGR28251.1 - 5.3 6.9 25.1 9.5 6.1 3.1 4.3 1 1 3 4 4 4 0 betaPIX coiled coil Cyclin PF08613.11 EGR28252.1 - 3.9e-34 118.4 1.2 4.7e-34 118.1 1.2 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EGR28252.1 - 3e-11 43.1 0.1 5.4e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain MORN PF02493.20 EGR28253.1 - 1.1e-49 163.5 81.8 4.9e-07 29.3 1.6 10.2 10 0 0 10 10 10 9 MORN repeat Rad60-SLD PF11976.8 EGR28255.1 - 7.1e-25 86.6 1.5 8.5e-25 86.4 1.5 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGR28255.1 - 6.8e-14 51.4 0.5 8.4e-14 51.1 0.5 1.1 1 0 0 1 1 1 1 Ubiquitin family DUF2057 PF09829.9 EGR28255.1 - 0.064 13.4 0.4 0.087 13.0 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) PAS PF00989.25 EGR28256.1 - 0.034 14.1 0.2 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 PAS fold Kelch_4 PF13418.6 EGR28257.1 - 4.5e-11 42.6 0.0 0.00018 21.4 0.0 3.4 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EGR28257.1 - 6.5e-10 38.8 0.0 0.015 15.3 0.0 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 EGR28257.1 - 5.5e-06 26.5 0.3 0.28 11.5 0.0 3.4 1 1 2 3 3 3 2 Kelch motif Kelch_2 PF07646.15 EGR28257.1 - 6.9e-06 25.8 0.0 0.32 11.1 0.0 3.2 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 EGR28257.1 - 0.00013 22.2 0.1 0.38 11.1 0.2 2.9 3 1 0 3 3 3 2 Galactose oxidase, central domain Kelch_1 PF01344.25 EGR28257.1 - 0.0032 17.0 0.0 0.94 9.1 0.0 3.0 3 0 0 3 3 3 1 Kelch motif RAG2 PF03089.14 EGR28257.1 - 0.072 12.1 0.0 0.63 9.0 0.0 2.1 1 1 1 2 2 2 0 Recombination activating protein 2 UNC-93 PF05978.16 EGR28258.1 - 1.9e-15 56.9 21.7 1.6e-14 53.9 17.9 2.8 1 1 1 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 EGR28258.1 - 2.8e-15 56.1 17.2 1.8e-13 50.1 18.4 2.0 1 1 0 1 1 1 1 Major Facilitator Superfamily TauE PF01925.19 EGR28258.1 - 0.00017 21.3 3.8 0.00017 21.3 3.8 2.7 2 1 1 3 3 3 1 Sulfite exporter TauE/SafE Gp5_OB PF06714.11 EGR28258.1 - 0.21 11.9 0.2 5.4 7.2 0.0 2.3 2 0 0 2 2 2 0 Gp5 N-terminal OB domain TPR_8 PF13181.6 EGR28260.1 - 1.8e-06 27.7 3.8 0.032 14.4 0.1 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGR28260.1 - 1.6e-05 24.5 4.3 0.00011 21.9 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGR28260.1 - 0.00033 20.9 0.8 0.031 14.6 0.1 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGR28260.1 - 0.00054 19.9 5.0 0.048 13.8 0.0 4.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGR28260.1 - 0.004 17.0 1.7 2.3 8.2 0.5 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat HH_signal PF01085.18 EGR28260.1 - 0.032 13.9 0.1 0.45 10.2 0.0 2.2 2 0 0 2 2 2 0 Hedgehog amino-terminal signalling domain TPR_7 PF13176.6 EGR28260.1 - 0.071 13.2 0.2 1.2 9.3 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.25 EGR28262.1 - 2.6e-58 197.5 0.1 2.6e-58 197.5 0.1 2.4 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28262.1 - 8.9e-47 159.5 0.0 1.9e-46 158.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28262.1 - 1.3e-09 37.8 0.1 4e-09 36.2 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR28262.1 - 1.7e-05 23.8 0.3 4e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGR28262.1 - 0.024 14.5 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3837 PF12939.7 EGR28262.1 - 1.4 9.3 14.1 2.4 8.6 1.8 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3837) Pkinase PF00069.25 EGR28263.1 - 2e-63 214.2 7.5 5e-63 212.9 7.5 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28263.1 - 3.2e-38 131.5 2.5 9.2e-38 130.0 2.5 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR28263.1 - 1.5e-05 24.4 1.4 2.3e-05 23.9 1.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGR28263.1 - 4.4e-05 22.9 0.1 0.0001 21.7 0.1 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR28263.1 - 0.004 16.0 0.0 0.01 14.7 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase DUF3346 PF11826.8 EGR28263.1 - 0.023 14.5 0.4 0.042 13.6 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3346) APH PF01636.23 EGR28263.1 - 0.033 14.1 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family GF_recep_IV PF14843.6 EGR28264.1 - 0.27 11.1 92.4 0.034 13.9 22.3 4.0 1 1 3 4 4 4 0 Growth factor receptor domain IV VSP PF03302.13 EGR28264.1 - 8 5.2 80.0 0.41 9.4 8.2 3.5 1 1 2 3 3 3 0 Giardia variant-specific surface protein SET PF00856.28 EGR28266.1 - 1.8e-14 54.5 6.4 1.8e-14 54.5 6.4 3.2 2 2 0 2 2 2 1 SET domain Bromodomain PF00439.25 EGR28266.1 - 1.4e-11 44.3 0.8 1.4e-11 44.3 0.8 2.7 2 0 0 2 2 2 1 Bromodomain C1_1 PF00130.22 EGR28266.1 - 0.0041 17.0 6.3 0.0041 17.0 6.3 7.0 4 2 3 7 7 7 3 Phorbol esters/diacylglycerol binding domain (C1 domain) NAD_binding_2 PF03446.15 EGR28267.1 - 1.2e-39 136.1 0.0 1.9e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EGR28267.1 - 1.9e-34 118.5 0.2 3.1e-34 117.8 0.2 1.3 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Shikimate_DH PF01488.20 EGR28267.1 - 0.0021 18.1 0.2 0.013 15.5 0.0 2.3 2 1 1 3 3 3 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.19 EGR28267.1 - 0.004 16.5 0.0 0.0074 15.7 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.25 EGR28268.1 - 7.8e-68 228.7 2.6 7.8e-68 228.7 2.6 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28268.1 - 7.7e-38 130.3 0.4 1.3e-37 129.5 0.4 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR28268.1 - 0.0004 19.3 4.0 0.0013 17.6 4.0 1.8 1 1 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EGR28268.1 - 0.011 15.4 0.4 0.011 15.4 0.4 2.5 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGR28268.1 - 0.015 14.7 0.2 0.027 13.8 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR28268.1 - 0.025 14.5 0.0 0.038 13.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ufd2P_core PF10408.9 EGR28270.1 - 9.1e-81 272.3 36.4 9.1e-55 186.4 21.3 2.0 1 1 1 2 2 2 2 Ubiquitin elongating factor core U-box PF04564.15 EGR28270.1 - 5.7e-17 61.7 0.1 1.6e-16 60.2 0.1 1.8 1 0 0 1 1 1 1 U-box domain EF-hand_8 PF13833.6 EGR28272.1 - 7.4e-09 35.3 1.4 3.9e-08 33.0 0.2 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 EGR28272.1 - 0.00022 21.6 11.4 0.0085 16.5 5.5 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR28272.1 - 0.0069 15.9 2.0 0.012 15.1 0.4 2.4 2 0 0 2 2 2 1 EF hand Acetyltransf_11 PF13720.6 EGR28272.1 - 0.18 12.3 1.9 0.47 10.9 0.2 2.5 2 1 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 AAA PF00004.29 EGR28273.1 - 8.8e-42 142.7 0.0 1.8e-41 141.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGR28273.1 - 4e-20 71.5 0.4 7.2e-20 70.7 0.4 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EGR28273.1 - 2.1e-09 37.0 0.0 4.5e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGR28273.1 - 2.2e-06 27.7 1.1 1.1e-05 25.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGR28273.1 - 1.5e-05 25.5 0.1 0.03 14.7 0.0 2.4 1 1 1 2 2 2 2 AAA ATPase domain RuvB_N PF05496.12 EGR28273.1 - 2.5e-05 24.1 0.0 6.6e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGR28273.1 - 0.00011 22.4 0.1 0.00069 19.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EGR28273.1 - 0.0023 17.4 0.2 0.0064 15.9 0.1 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 EGR28273.1 - 0.0043 17.3 0.5 0.44 10.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_24 PF13479.6 EGR28273.1 - 0.005 16.6 1.0 0.01 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGR28273.1 - 0.014 14.9 0.1 0.044 13.3 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region DUF815 PF05673.13 EGR28273.1 - 0.017 14.3 0.0 0.031 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_33 PF13671.6 EGR28273.1 - 0.023 14.8 0.0 0.052 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF496 PF04363.12 EGR28273.1 - 0.028 14.5 3.3 0.028 14.5 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF496) PhoH PF02562.16 EGR28273.1 - 0.032 13.7 0.0 0.084 12.3 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein IstB_IS21 PF01695.17 EGR28273.1 - 0.04 13.7 0.0 0.1 12.3 0.0 1.7 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 EGR28273.1 - 0.067 13.0 3.0 0.66 9.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGR28273.1 - 0.071 12.7 0.3 0.64 9.6 0.1 2.3 1 1 1 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGR28273.1 - 0.085 13.3 0.1 0.3 11.5 0.0 2.0 2 0 0 2 2 2 0 RNA helicase ATPase PF06745.13 EGR28273.1 - 0.2 11.0 0.0 0.2 11.0 0.0 3.1 4 0 0 4 4 4 0 KaiC JMY PF15871.5 EGR28273.1 - 0.42 9.8 4.1 0.69 9.1 4.1 1.3 1 0 0 1 1 1 0 Junction-mediating and -regulatory protein Pep3_Vps18 PF05131.14 EGR28275.1 - 8.7e-09 35.3 0.2 1.8e-08 34.3 0.2 1.6 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family NDUF_B4 PF07225.12 EGR28275.1 - 0.049 13.5 0.3 0.18 11.7 0.0 2.0 3 0 0 3 3 3 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) RIH_assoc PF08454.11 EGR28275.1 - 0.15 11.9 6.2 0.17 11.7 3.2 2.2 1 1 1 2 2 2 0 RyR and IP3R Homology associated Pkinase PF00069.25 EGR28276.1 - 1.3e-12 47.7 0.3 2e-12 47.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28276.1 - 0.00096 18.5 0.1 0.0012 18.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Beta-lactamase2 PF13354.6 EGR28276.1 - 0.069 12.7 0.1 0.084 12.5 0.1 1.1 1 0 0 1 1 1 0 Beta-lactamase enzyme family Pkinase PF00069.25 EGR28277.1 - 4e-10 39.5 0.0 4.6e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28277.1 - 0.0026 17.1 0.0 0.0033 16.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase ThylakoidFormat PF11264.8 EGR28277.1 - 0.012 15.3 0.0 0.013 15.2 0.0 1.1 1 0 0 1 1 1 0 Thylakoid formation protein Scramblase PF03803.15 EGR28278.1 - 1.2e-30 106.5 0.5 2.2e-30 105.6 0.5 1.4 1 1 0 1 1 1 1 Scramblase SUKH_5 PF14567.6 EGR28278.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall Metallophos PF00149.28 EGR28279.1 - 3.1e-34 119.3 1.4 4.2e-34 118.8 1.4 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ion_trans PF00520.31 EGR28280.1 - 0.0018 17.6 6.8 0.0027 17.0 6.8 1.3 1 0 0 1 1 1 1 Ion transport protein Pkinase PF00069.25 EGR28281.1 - 8.2e-65 218.8 0.5 1.2e-64 218.3 0.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28281.1 - 5.9e-32 111.0 0.1 9.5e-32 110.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase UQ_con PF00179.26 EGR28281.1 - 1.2e-17 63.8 0.4 2.9e-17 62.6 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme APH PF01636.23 EGR28281.1 - 1.2e-05 25.3 0.0 0.00014 21.9 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR28281.1 - 0.0091 15.4 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR28281.1 - 0.028 13.2 0.0 0.07 11.9 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase RWD PF05773.22 EGR28281.1 - 0.21 11.9 3.7 0.1 12.9 0.6 2.3 2 2 0 2 2 2 0 RWD domain RR_TM4-6 PF06459.12 EGR28282.1 - 2.5 7.9 8.5 6.4 6.5 8.5 1.7 1 1 0 1 1 1 0 Ryanodine Receptor TM 4-6 CKS PF01111.19 EGR28283.1 - 1.6e-37 127.5 1.6 1.9e-37 127.3 1.6 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF2475 PF10629.9 EGR28284.1 - 9.7e-09 35.3 2.1 0.027 14.7 0.2 4.2 3 0 0 3 3 3 3 Protein of unknown function (DUF2475) CHCH PF06747.13 EGR28285.1 - 0.0021 18.1 5.2 0.0021 18.1 5.2 1.6 2 0 0 2 2 2 1 CHCH domain HrpB7 PF09486.10 EGR28285.1 - 0.021 15.2 1.7 0.083 13.3 0.7 2.0 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF4834 PF16118.5 EGR28285.1 - 1.9 9.5 6.4 0.58 11.2 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 EGR28285.1 - 6 6.8 15.3 7.9 6.4 15.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_63 PF03200.16 EGR28287.1 - 2.2e-58 198.2 11.9 2.3e-35 122.3 3.7 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 63 C-terminal domain Peptidase_M24 PF00557.24 EGR28288.1 - 4.4e-30 104.9 0.4 1.7e-19 70.4 0.0 2.0 1 1 1 2 2 2 2 Metallopeptidase family M24 DUF3139 PF11337.8 EGR28288.1 - 0.12 13.1 0.1 0.24 12.1 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) MCM PF00493.23 EGR28289.1 - 3.5e-86 287.9 0.3 5.3e-86 287.3 0.3 1.2 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 EGR28289.1 - 1e-08 34.8 0.2 1.6e-05 24.4 0.0 2.7 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGR28289.1 - 4.4e-08 33.2 0.0 1.2e-07 31.9 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EGR28289.1 - 4.7e-05 23.2 0.0 0.00016 21.5 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 EGR28289.1 - 8.4e-05 23.0 0.1 0.0003 21.2 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGR28289.1 - 0.00024 20.9 0.1 0.0017 18.1 0.1 2.3 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 EGR28289.1 - 0.00037 20.4 0.0 0.00097 19.0 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGR28289.1 - 0.0031 17.9 0.1 0.0095 16.3 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.6 EGR28289.1 - 0.014 15.7 0.1 4.9 7.5 0.0 2.6 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.13 EGR28289.1 - 0.017 14.3 0.0 0.047 12.8 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 EGR28289.1 - 0.019 15.2 1.4 0.29 11.4 0.2 3.3 2 1 1 3 3 3 0 AAA domain ABC_tran PF00005.27 EGR28289.1 - 0.058 13.9 0.2 0.058 13.9 0.2 2.5 2 1 0 2 2 2 0 ABC transporter NACHT PF05729.12 EGR28289.1 - 0.087 12.7 0.7 1.1 9.1 0.1 2.6 1 1 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 EGR28289.1 - 0.12 12.5 1.0 0.37 10.9 0.2 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase FERM_M PF00373.18 EGR28289.1 - 1.6 9.2 9.5 3.3 8.2 4.8 2.6 2 1 0 2 2 1 0 FERM central domain RNA_helicase PF00910.22 EGR28289.1 - 2.9 8.3 7.4 0.6 10.5 0.2 3.2 3 1 0 3 3 2 0 RNA helicase Ion_trans_2 PF07885.16 EGR28290.1 - 4.4e-15 55.4 1.1 8.2e-15 54.5 1.1 1.5 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 EGR28290.1 - 1.3e-09 38.0 0.0 2.6e-09 37.0 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 EGR28290.1 - 2.5e-08 33.4 1.5 4.6e-08 32.6 1.5 1.5 1 0 0 1 1 1 1 Ion transport protein S10_plectin PF03501.15 EGR28291.1 - 3.1e-28 97.7 0.0 4.1e-28 97.3 0.0 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 EGR28291.1 - 0.02 14.8 0.0 0.068 13.1 0.0 1.9 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB GRP PF07172.11 EGR28291.1 - 0.31 11.7 8.1 0.58 10.9 8.1 1.4 1 0 0 1 1 1 0 Glycine rich protein family DAGK_acc PF00609.19 EGR28292.1 - 3.2e-31 108.8 2.0 1.4e-30 106.8 2.0 2.2 1 1 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 EGR28292.1 - 4.8e-14 52.1 0.1 1.1e-13 50.8 0.1 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain LpxB PF02684.15 EGR28294.1 - 2.5e-14 52.9 3.6 5.6e-09 35.3 0.5 2.9 3 0 0 3 3 3 2 Lipid-A-disaccharide synthetase RIH_assoc PF08454.11 EGR28294.1 - 1.1 9.2 5.4 0.45 10.4 1.7 2.2 2 1 0 2 2 2 0 RyR and IP3R Homology associated Abhydrolase_2 PF02230.16 EGR28295.1 - 0.048 13.5 0.0 0.051 13.4 0.0 1.0 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase PP2C PF00481.21 EGR28296.1 - 8e-53 179.7 0.0 9.6e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGR28296.1 - 0.15 11.7 0.0 0.47 10.0 0.0 1.8 1 1 0 1 1 1 0 Protein phosphatase 2C MORN PF02493.20 EGR28298.1 - 2.2e-17 61.8 42.2 0.00019 21.1 1.5 7.4 7 0 0 7 7 7 6 MORN repeat Peptidase_C2 PF00648.21 EGR28298.1 - 2.4e-12 46.5 1.1 3.8e-12 45.9 1.1 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease GBP PF02263.19 EGR28299.1 - 1.1e-51 175.6 0.0 1.1e-51 175.6 0.0 3.9 2 1 1 4 4 4 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 EGR28299.1 - 4.3e-13 49.3 26.2 4.3e-13 49.3 26.2 2.7 2 1 0 2 2 2 1 Guanylate-binding protein, C-terminal domain Pkinase PF00069.25 EGR28300.1 - 2.1e-52 178.1 1.8 6.3e-47 160.1 0.3 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28300.1 - 2e-14 53.5 0.1 3.4e-12 46.2 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EGR28300.1 - 3.8e-07 30.3 0.0 5.8e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGR28300.1 - 0.021 14.2 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Choline_kinase PF01633.20 EGR28300.1 - 0.027 14.1 0.5 0.027 14.1 0.5 2.8 3 0 0 3 3 3 0 Choline/ethanolamine kinase Kdo PF06293.14 EGR28300.1 - 0.045 13.1 0.0 0.075 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGR28300.1 - 0.05 13.2 1.7 0.075 12.6 0.5 1.9 2 1 0 2 2 2 0 RIO1 family Pkinase_fungal PF17667.1 EGR28300.1 - 0.078 11.7 0.1 0.12 11.1 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase ASH PF15780.5 EGR28301.1 - 5.1e-14 52.3 0.4 1e-05 25.6 0.2 5.1 4 0 0 4 4 4 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 EGR28301.1 - 6.8e-07 29.1 14.3 0.0059 16.4 0.0 6.1 6 0 0 6 6 6 3 MSP (Major sperm protein) domain TMEM131_like PF12371.8 EGR28301.1 - 0.0001 22.5 3.6 3.7 7.9 0.2 5.1 4 0 0 4 4 4 2 Transmembrane protein 131-like Transglut_C PF00927.22 EGR28301.1 - 0.0019 18.3 2.4 0.89 9.7 0.0 4.7 5 0 0 5 5 5 1 Transglutaminase family, C-terminal ig like domain Pkinase PF00069.25 EGR28302.1 - 8.1e-36 123.7 1.3 5.7e-35 121.0 1.3 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28302.1 - 8.6e-18 64.5 0.1 3.3e-15 56.1 0.1 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR28302.1 - 6.3e-06 25.2 0.1 1.7e-05 23.8 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 EGR28302.1 - 0.0086 15.7 1.1 0.41 10.2 0.1 2.2 1 1 1 2 2 2 2 RIO1 family Choline_kinase PF01633.20 EGR28302.1 - 0.013 15.1 0.4 0.02 14.5 0.4 1.4 1 1 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 EGR28302.1 - 0.014 15.3 0.0 0.028 14.3 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGR28302.1 - 0.066 12.6 0.9 0.083 12.2 0.9 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGR28302.1 - 0.13 11.9 1.1 0.3 10.7 1.0 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Mito_carr PF00153.27 EGR28303.1 - 3.6e-50 167.8 5.8 9.2e-22 76.8 0.1 4.0 3 1 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.22 EGR28304.1 - 2.5e-59 199.5 2.4 3e-59 199.3 2.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR28304.1 - 8.2e-32 110.0 1.5 1.3e-31 109.3 1.5 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR28304.1 - 1e-14 54.4 1.1 1.2e-14 54.2 1.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGR28304.1 - 3.7e-05 23.2 0.3 4.1e-05 23.1 0.3 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 EGR28304.1 - 4.1e-05 23.5 0.8 0.00011 22.0 0.0 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EGR28304.1 - 0.00013 22.0 0.1 0.051 13.5 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EGR28304.1 - 0.0012 18.2 1.2 0.0027 17.1 1.2 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGR28304.1 - 0.002 17.7 2.1 0.0031 17.1 0.5 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGR28304.1 - 0.0046 17.0 0.3 0.0078 16.3 0.3 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase XPG_I PF00867.18 EGR28305.1 - 4.3e-27 94.3 0.0 4.3e-27 94.3 0.0 3.0 3 1 1 4 4 4 1 XPG I-region 5_3_exonuc PF01367.20 EGR28305.1 - 3.8e-05 24.2 0.0 3.8e-05 24.2 0.0 2.8 2 2 1 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold DUF863 PF05904.11 EGR28305.1 - 0.025 13.0 0.1 0.036 12.5 0.1 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF863) Cren7 PF11520.8 EGR28306.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Chromatin protein Cren7 DUF1664 PF07889.12 EGR28306.1 - 5.2 7.1 9.9 0.89 9.6 4.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) HECT PF00632.25 EGR28307.1 - 6.8e-32 111.2 0.5 7e-22 78.3 0.2 2.0 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) Sigma54_activ_2 PF14532.6 EGR28307.1 - 0.062 13.4 0.0 0.097 12.8 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain SpoIIE PF07228.12 EGR28308.1 - 1.5e-10 41.3 0.0 4.3e-10 39.8 0.0 1.7 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EGR28308.1 - 3.6e-05 23.5 0.0 0.011 15.3 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 EGR28308.1 - 0.0014 18.3 0.0 0.0056 16.3 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C UME PF08064.13 EGR28308.1 - 0.0088 15.9 0.3 0.13 12.2 0.0 2.3 2 0 0 2 2 2 1 UME (NUC010) domain HEAT PF02985.22 EGR28308.1 - 0.051 13.8 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 HEAT repeat HEAT_2 PF13646.6 EGR28308.1 - 0.22 12.0 0.0 0.45 10.9 0.0 1.5 1 0 0 1 1 1 0 HEAT repeats DUF3861 PF12977.7 EGR28308.1 - 0.41 10.9 0.0 0.41 10.9 0.0 3.1 3 1 1 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) T3SS_ATPase_C PF18269.1 EGR28308.1 - 0.83 9.6 3.5 0.57 10.1 1.0 2.0 2 0 0 2 2 2 0 T3SS EscN ATPase C-terminal domain Cyclin_N PF00134.23 EGR28309.1 - 9e-28 96.6 2.1 1.1e-27 96.3 2.1 1.0 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF5624 PF18538.1 EGR28309.1 - 0.06 13.5 0.5 11 6.1 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5624) Flu_B_M2 PF04772.12 EGR28309.1 - 0.11 12.7 1.5 0.44 10.8 0.1 2.1 2 1 0 2 2 2 0 Influenza B matrix protein 2 (BM2) Pkinase PF00069.25 EGR28311.1 - 3.1e-54 184.1 0.0 5.2e-54 183.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Transketolase_N PF00456.21 EGR28311.1 - 6e-45 153.6 0.0 1.1e-44 152.8 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EGR28311.1 - 6.1e-32 110.7 0.0 1e-31 110.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Pkinase_Tyr PF07714.17 EGR28311.1 - 5.3e-24 84.9 0.0 8e-24 84.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Transketolase_C PF02780.20 EGR28311.1 - 1.1e-23 83.4 0.3 2.3e-23 82.4 0.3 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 EGR28311.1 - 1.6e-06 27.3 0.0 3.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Dehydrogenase E1 component Pkinase_fungal PF17667.1 EGR28311.1 - 1.9e-05 23.7 0.0 3.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR28311.1 - 0.0048 16.8 0.1 0.009 16.0 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR28311.1 - 0.008 15.5 0.1 0.015 14.7 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPP_enzyme_C PF02775.21 EGR28311.1 - 0.047 13.5 0.2 0.83 9.4 0.1 2.8 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain ADK PF00406.22 EGR28312.1 - 6.1e-35 120.6 0.1 7.6e-35 120.2 0.1 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGR28312.1 - 3.8e-18 66.2 0.0 7.7e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 EGR28312.1 - 1.6e-10 40.8 3.5 2.6e-10 40.1 3.5 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_18 PF13238.6 EGR28312.1 - 1e-06 29.3 0.0 1.7e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGR28312.1 - 0.0054 16.9 0.0 0.009 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGR28312.1 - 0.054 13.8 0.0 0.086 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGR28312.1 - 0.099 13.1 0.2 0.19 12.2 0.2 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2004 PF09406.10 EGR28312.1 - 0.12 12.7 0.1 0.5 10.7 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF2004) zf-ZPR1 PF03367.13 EGR28312.1 - 0.18 11.6 2.1 0.35 10.7 0.1 2.2 2 0 0 2 2 2 0 ZPR1 zinc-finger domain DUF5411 PF17424.2 EGR28313.1 - 5.3 7.0 15.9 5.6 6.9 7.2 3.1 2 1 0 2 2 2 0 Family of unknown function (DUF5411) Ribosomal_L18 PF17135.4 EGR28314.1 - 1.4e-47 161.6 1.0 7.3e-46 155.9 0.1 2.0 1 1 1 2 2 2 2 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EGR28314.1 - 0.0037 17.9 0.5 0.0054 17.4 0.0 1.7 2 1 0 2 2 2 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Abhydrolase_1 PF00561.20 EGR28315.1 - 4.3e-25 88.8 0.0 6.4e-25 88.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGR28315.1 - 1.5e-18 66.9 0.0 2.1e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGR28315.1 - 1.4e-14 55.3 0.0 1.7e-14 54.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 EGR28315.1 - 8.3e-10 38.6 0.2 1.5e-09 37.9 0.2 1.4 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Ndr PF03096.14 EGR28315.1 - 3.7e-09 35.7 0.0 5e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Ndr family DUF915 PF06028.11 EGR28315.1 - 2.4e-06 27.1 0.2 0.0026 17.1 0.1 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Thioesterase PF00975.20 EGR28315.1 - 3.3e-05 24.1 0.0 4.7e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Chlorophyllase2 PF12740.7 EGR28315.1 - 4.3e-05 22.6 0.1 6.2e-05 22.0 0.1 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 EGR28315.1 - 7e-05 22.7 0.1 0.00017 21.4 0.0 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 EGR28315.1 - 0.00013 21.9 0.0 0.0017 18.2 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase PGAP1 PF07819.13 EGR28315.1 - 0.00055 19.7 0.1 0.0056 16.4 0.1 2.2 1 1 1 2 2 2 1 PGAP1-like protein Esterase PF00756.20 EGR28315.1 - 0.00068 19.4 0.0 0.0015 18.3 0.0 1.7 1 1 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 EGR28315.1 - 0.0008 19.3 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.12 EGR28315.1 - 0.0011 19.0 0.4 0.0035 17.3 0.2 1.9 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) DUF676 PF05057.14 EGR28315.1 - 0.0021 17.6 0.1 0.0094 15.5 0.0 2.1 2 1 0 2 2 2 1 Putative serine esterase (DUF676) DUF2974 PF11187.8 EGR28315.1 - 0.011 15.4 0.0 0.02 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Lipase_3 PF01764.25 EGR28315.1 - 0.012 15.5 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) UPF0113_N PF17833.1 EGR28315.1 - 0.019 15.5 0.8 1.2 9.7 0.0 2.4 2 0 0 2 2 2 0 UPF0113 Pre-PUA domain Abhydrolase_2 PF02230.16 EGR28315.1 - 0.032 14.0 0.1 0.21 11.3 0.0 2.1 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 EGR28315.1 - 0.036 14.0 0.0 0.079 12.9 0.0 1.5 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 EGR28315.1 - 0.04 13.4 0.0 1.3 8.5 0.0 2.1 1 1 1 2 2 2 0 Prolyl oligopeptidase family EHN PF06441.12 EGR28315.1 - 0.23 11.8 1.7 6.1 7.3 0.0 2.7 2 1 1 3 3 3 0 Epoxide hydrolase N terminus POLO_box PF00659.18 EGR28317.1 - 4.7e-38 129.2 3.5 6.2e-19 67.9 0.1 2.7 2 0 0 2 2 2 2 POLO box duplicated region Pkinase PF00069.25 EGR28317.1 - 1.6e-05 24.4 0.9 3.8e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Ndufs5 PF10200.9 EGR28317.1 - 0.017 15.4 0.0 1.5 9.1 0.0 2.7 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Plk4_PB2 PF18409.1 EGR28317.1 - 0.021 15.5 9.1 0.23 12.2 0.5 2.7 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 PX PF00787.24 EGR28318.1 - 1.1e-17 64.0 0.9 1.3e-17 63.8 0.9 1.1 1 0 0 1 1 1 1 PX domain EF_TS PF00889.19 EGR28319.1 - 2.3e-39 135.2 9.3 5.5e-39 133.9 9.3 1.6 1 1 0 1 1 1 1 Elongation factor TS SRI PF08236.11 EGR28319.1 - 0.24 11.6 5.5 9.8 6.4 0.5 3.0 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain DNA_PPF PF02916.15 EGR28319.1 - 0.51 10.8 4.9 0.7 10.3 0.4 2.5 2 0 0 2 2 2 0 DNA polymerase processivity factor ArfGap PF01412.18 EGR28319.1 - 0.53 10.4 6.6 1.8 8.7 1.1 2.5 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf AAA_14 PF13173.6 EGR28319.1 - 8.9 6.4 9.0 1.5 8.9 1.7 2.7 2 1 0 2 2 2 0 AAA domain L27_2 PF09045.10 EGR28321.1 - 0.027 14.4 0.2 0.07 13.1 0.2 1.7 1 0 0 1 1 1 0 L27_2 DUF4312 PF14189.6 EGR28322.1 - 3.3 7.8 8.3 0.64 10.1 0.8 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4312) EPV_E5 PF08135.11 EGR28323.1 - 0.49 10.8 6.0 0.65 10.4 1.0 3.2 3 0 0 3 3 3 0 Major transforming protein E5 family EBP PF05241.12 EGR28324.1 - 4.9e-22 78.3 7.0 8.1e-22 77.5 7.0 1.3 1 0 0 1 1 1 1 Emopamil binding protein ATE_N PF04376.13 EGR28324.1 - 4.9e-19 68.5 2.6 9e-19 67.7 2.6 1.4 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus ATE_C PF04377.15 EGR28324.1 - 1e-06 29.4 0.2 5.7e-06 27.0 0.1 2.1 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus Ank_2 PF12796.7 EGR28325.1 - 2.6e-09 37.5 0.1 3.6e-09 37.1 0.1 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGR28325.1 - 1.1e-08 35.5 0.4 0.00068 20.2 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR28325.1 - 2.3e-06 27.5 0.1 0.018 15.5 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EGR28325.1 - 4.3e-06 26.9 0.1 1.2e-05 25.4 0.0 1.8 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EGR28325.1 - 0.14 12.7 0.0 0.57 10.7 0.0 2.0 1 1 1 2 2 2 0 Ankyrin repeat Rdx PF10262.9 EGR28326.1 - 0.00051 20.2 2.6 0.0017 18.5 0.2 3.1 3 0 0 3 3 3 1 Rdx family EphA2_TM PF14575.6 EGR28326.1 - 0.042 14.7 0.3 0.042 14.7 0.3 3.3 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 EGR28326.1 - 0.18 12.0 1.5 0.47 10.7 1.5 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator ODV-E18 PF10717.9 EGR28326.1 - 7.8 6.5 7.3 19 5.2 7.3 1.7 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Fumble PF03630.14 EGR28327.1 - 1.8e-95 319.9 5.7 2.1e-95 319.7 5.7 1.0 1 0 0 1 1 1 1 Fumble DUF2577 PF10844.8 EGR28327.1 - 0.017 15.3 0.1 0.035 14.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2577) Tudor_FRX1 PF18336.1 EGR28327.1 - 0.097 12.6 0.0 1.1 9.2 0.1 2.5 2 0 0 2 2 2 0 Fragile X mental retardation Tudor domain GSHPx PF00255.19 EGR28328.1 - 1.8e-06 27.5 4.6 0.00011 21.8 0.4 2.6 1 1 1 2 2 2 2 Glutathione peroxidase DUF4174 PF13778.6 EGR28328.1 - 0.015 15.7 0.5 0.031 14.7 0.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4174) Choline_transpo PF04515.12 EGR28329.1 - 3.5e-72 243.4 30.8 3.5e-72 243.4 30.8 2.8 2 1 1 3 3 3 2 Plasma-membrane choline transporter FlhD PF05247.13 EGR28329.1 - 0.1 12.9 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhD) DUF3307 PF11750.8 EGR28329.1 - 1.1 9.3 6.7 0.085 12.9 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3307) DUF4834 PF16118.5 EGR28330.1 - 0.013 16.4 7.5 2 9.5 2.4 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF4446 PF14584.6 EGR28330.1 - 0.021 14.8 0.9 0.26 11.3 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) Phage_holin_6_1 PF09682.10 EGR28331.1 - 1.6 9.2 10.9 2.7 8.4 1.2 2.4 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF4407 PF14362.6 EGR28331.1 - 1.8 7.9 17.7 2 7.7 17.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WD40 PF00400.32 EGR28332.1 - 5.7e-09 36.5 1.2 0.0016 19.2 0.1 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR28332.1 - 0.00022 21.5 0.3 0.029 14.7 0.2 2.8 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EGR28332.1 - 0.009 15.9 0.0 3.1 7.9 0.0 2.5 2 0 0 2 2 2 2 WD40-like Beta Propeller Repeat PSII_BNR PF14870.6 EGR28332.1 - 0.032 13.5 0.6 0.052 12.8 0.6 1.3 1 1 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 IKI3 PF04762.12 EGR28332.1 - 0.051 11.6 1.4 1.7 6.5 2.2 1.9 1 1 0 2 2 2 0 IKI3 family MORN PF02493.20 EGR28333.1 - 8.2e-25 85.2 39.0 2.3e-05 24.0 1.4 7.0 7 0 0 7 7 7 6 MORN repeat DUF4505 PF14956.6 EGR28334.1 - 0.034 13.9 0.0 0.034 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) Pkinase PF00069.25 EGR28335.1 - 3.4e-68 229.9 0.2 4.7e-68 229.4 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28335.1 - 8.8e-38 130.1 0.1 1.3e-37 129.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28335.1 - 0.00028 20.3 0.0 0.0046 16.3 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR28335.1 - 0.0013 17.6 0.0 0.0031 16.4 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EGR28335.1 - 0.0025 16.9 0.1 0.0041 16.2 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Spc7 PF08317.11 EGR28336.1 - 0.00039 19.4 11.0 0.00039 19.4 11.0 2.4 1 1 0 2 2 2 1 Spc7 kinetochore protein NPA PF16469.5 EGR28336.1 - 0.22 12.1 7.0 2.5 8.7 0.6 3.0 3 0 0 3 3 3 0 Nematode polyprotein allergen ABA-1 Cep57_MT_bd PF06657.13 EGR28336.1 - 0.41 11.1 7.5 5.2 7.6 0.5 3.7 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF2232 PF09991.9 EGR28336.1 - 0.42 9.8 1.4 0.87 8.7 1.4 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF2089 PF09862.9 EGR28336.1 - 2.7 8.1 13.4 1 9.4 0.5 3.9 1 1 1 3 3 3 0 Protein of unknown function (DUF2089) Nbl1_Borealin_N PF10444.9 EGR28336.1 - 4.9 6.9 7.5 0.44 10.2 0.9 2.9 3 1 0 3 3 3 0 Nbl1 / Borealin N terminal DUF1515 PF07439.11 EGR28336.1 - 9.3 6.3 6.5 1.5 8.9 0.4 2.7 2 2 1 3 3 3 0 Protein of unknown function (DUF1515) PI3_PI4_kinase PF00454.27 EGR28337.1 - 5.2e-28 98.5 2.2 3e-24 86.2 1.9 4.6 2 2 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase DUF366 PF04017.12 EGR28338.1 - 0.044 13.3 0.4 0.11 11.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF366) AMP-binding PF00501.28 EGR28339.1 - 2.7e-86 289.8 0.0 3.4e-86 289.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme SF3A2 PF16835.5 EGR28340.1 - 2.6e-22 79.0 0.2 4.9e-22 78.1 0.2 1.5 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) CactinC_cactus PF09732.9 EGR28340.1 - 0.00015 21.7 0.1 0.0002 21.3 0.1 1.2 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cyclin_C PF02984.19 EGR28341.1 - 1e-07 32.1 0.2 1.6e-07 31.5 0.2 1.3 1 0 0 1 1 1 1 Cyclin, C-terminal domain Peptidase_M16_M PF16187.5 EGR28343.1 - 6.5e-54 183.1 15.3 6.5e-54 183.1 15.3 1.7 2 0 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EGR28343.1 - 6.9e-22 78.0 0.6 6.9e-17 61.8 0.0 3.9 2 1 1 3 3 3 2 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGR28343.1 - 4.9e-12 46.2 3.2 1.8e-11 44.4 3.2 1.9 1 0 0 1 1 1 1 Peptidase M16 inactive domain SHIPPO-rpt PF07004.12 EGR28344.1 - 0.012 16.5 31.2 0.21 12.5 0.2 6.3 6 0 0 6 6 6 0 Sperm-tail PG-rich repeat Peptidase_C1 PF00112.23 EGR28345.1 - 3.6e-65 220.1 5.3 5.1e-65 219.6 5.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Propeptide_C1 PF08127.13 EGR28345.1 - 2.9e-07 30.3 0.4 2.9e-07 30.3 0.4 1.9 2 0 0 2 2 2 1 Peptidase family C1 propeptide Peptidase_C1_2 PF03051.15 EGR28345.1 - 0.036 12.8 2.4 3.3 6.4 0.1 2.2 2 0 0 2 2 2 0 Peptidase C1-like family zf-LITAF-like PF10601.9 EGR28346.1 - 1e-14 54.5 15.6 1.9e-14 53.7 15.6 1.4 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Pkinase PF00069.25 EGR28347.1 - 5.1e-53 180.1 0.6 5.8e-53 179.9 0.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28347.1 - 1e-33 116.7 0.1 1.2e-33 116.6 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28347.1 - 1.1e-08 34.8 0.0 1.3e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGR28347.1 - 0.00012 22.1 0.5 0.0002 21.4 0.5 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGR28347.1 - 0.00018 20.4 0.0 0.00023 20.1 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 EGR28347.1 - 0.00025 20.7 0.7 0.00037 20.1 0.7 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 EGR28347.1 - 0.00048 19.2 0.4 0.00076 18.5 0.4 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGR28347.1 - 0.002 17.5 0.6 0.0038 16.6 0.3 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EGR28348.1 - 5.3e-63 212.8 0.6 6.2e-63 212.6 0.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28348.1 - 2.3e-39 135.3 0.1 2.9e-39 134.9 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28348.1 - 2.3e-05 23.9 0.0 3.3e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR28348.1 - 7e-05 21.8 0.0 0.0001 21.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGR28348.1 - 0.00014 21.0 0.2 0.0002 20.4 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGR28348.1 - 0.057 13.3 0.0 0.14 12.0 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family Prok-RING_4 PF14447.6 EGR28349.1 - 0.098 12.5 0.3 0.18 11.7 0.3 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC PF07967.13 EGR28349.1 - 0.4 10.7 4.3 0.11 12.5 1.0 1.8 2 0 0 2 2 2 0 C3HC zinc finger-like DUF5390 PF17365.2 EGR28349.1 - 1.9 8.7 11.4 0.24 11.7 5.6 2.5 2 1 0 2 2 2 0 Family of unknown function (DUF5390) V_ATPase_I PF01496.19 EGR28351.1 - 2.5e-120 402.8 24.5 3.1e-120 402.5 24.5 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TMEM40 PF15817.5 EGR28351.1 - 1.3 8.8 5.9 6.2 6.6 0.2 2.6 2 1 0 2 2 2 0 Transmembrane protein 40 family V_ATPase_I PF01496.19 EGR28352.1 - 5.1e-75 252.9 23.7 8.9e-74 248.8 23.7 2.0 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family HJURP_C PF12347.8 EGR28352.1 - 0.062 13.3 3.5 0.21 11.6 0.3 2.9 2 0 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat EF-hand_7 PF13499.6 EGR28353.1 - 1.1e-12 48.2 7.2 2e-10 41.0 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGR28353.1 - 5.1e-07 29.4 2.8 0.00018 21.3 0.2 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR28353.1 - 1.3e-06 27.5 1.2 1.3e-06 27.5 1.2 4.5 4 2 1 5 5 5 1 EF hand EF-hand_6 PF13405.6 EGR28353.1 - 4.1e-06 26.3 10.2 0.0059 16.4 2.3 4.3 3 2 1 4 4 4 2 EF-hand domain EF-hand_9 PF14658.6 EGR28353.1 - 5.3e-05 23.5 0.0 0.03 14.6 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EGR28353.1 - 8.1e-05 22.5 1.4 0.00017 21.5 0.1 2.0 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 EGR28353.1 - 0.0055 16.2 0.8 0.027 13.9 0.8 2.2 1 0 0 1 1 1 1 EF hand Vps23_core PF09454.10 EGR28353.1 - 0.051 13.5 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Vps23 core domain Pkinase PF00069.25 EGR28354.1 - 1.8e-55 188.1 2.0 1.8e-55 188.1 2.0 3.2 2 2 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28354.1 - 1.5e-37 129.3 4.3 9.8e-37 126.6 0.5 2.6 2 1 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 EGR28354.1 - 5.8e-07 29.1 0.0 5.8e-07 29.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like LAP1C PF05609.12 EGR28354.1 - 0.0028 16.8 22.3 0.0041 16.3 22.3 1.2 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) Pkinase PF00069.25 EGR28355.1 - 2.4e-68 230.4 0.0 2.9e-68 230.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28355.1 - 3.9e-35 121.4 0.0 5.1e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28355.1 - 0.00049 19.5 0.0 0.00076 18.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR28355.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGR28355.1 - 0.027 13.4 0.2 0.041 12.8 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain GDPD PF03009.17 EGR28357.1 - 2.3e-30 106.2 1.3 2.7e-30 106.0 0.1 1.7 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family UPF0020 PF01170.18 EGR28357.1 - 2.3e-10 40.5 0.0 7.8e-10 38.8 0.0 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 EGR28357.1 - 0.00016 21.4 0.3 0.4 10.3 0.0 2.6 2 1 0 2 2 2 2 DNA methylase Hydrolase_4 PF12146.8 EGR28358.1 - 7e-07 28.8 0.0 0.0027 17.0 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EGR28358.1 - 0.002 17.8 0.0 0.031 13.9 0.0 2.1 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 EGR28358.1 - 0.0028 17.4 0.1 0.0044 16.7 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EGR28358.1 - 0.0038 17.1 0.6 0.11 12.3 0.0 2.7 1 1 1 3 3 3 1 Phospholipase/Carboxylesterase DLH PF01738.18 EGR28358.1 - 0.0051 16.4 0.1 0.1 12.1 0.1 2.7 1 1 0 1 1 1 1 Dienelactone hydrolase family DUF1057 PF06342.12 EGR28358.1 - 0.0083 15.2 0.5 0.013 14.5 0.2 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Peptidase_S9 PF00326.21 EGR28358.1 - 0.027 13.9 0.0 0.044 13.2 0.0 1.5 1 1 0 1 1 1 0 Prolyl oligopeptidase family Cutinase PF01083.22 EGR28358.1 - 0.058 13.3 0.0 0.082 12.9 0.0 1.2 1 0 0 1 1 1 0 Cutinase Ycf15 PF10705.9 EGR28358.1 - 0.25 11.5 3.8 0.28 11.4 0.4 2.4 2 0 0 2 2 2 0 Chloroplast protein precursor Ycf15 putative UCH PF00443.29 EGR28359.1 - 1.1e-66 225.0 29.6 2.4e-40 138.7 7.0 2.9 1 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EGR28359.1 - 2.8e-13 50.3 8.3 2.8e-13 50.3 8.3 5.8 5 1 0 5 5 5 1 DUSP domain zf-MYND PF01753.18 EGR28359.1 - 0.011 15.8 11.8 0.011 15.8 11.8 2.6 3 0 0 3 3 3 0 MYND finger DFRP_C PF16543.5 EGR28359.1 - 0.61 10.6 5.7 10 6.7 0.0 3.4 3 0 0 3 3 3 0 DRG Family Regulatory Proteins, Tma46 DUF4312 PF14189.6 EGR28359.1 - 7.5 6.6 11.8 22 5.1 0.4 4.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4312) Isochorismatase PF00857.20 EGR28360.1 - 4.8e-26 92.0 0.2 5.7e-26 91.7 0.2 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF5034 PF16437.5 EGR28360.1 - 0.013 15.5 0.6 0.029 14.4 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF5034) Pkinase PF00069.25 EGR28361.1 - 1.6e-62 211.3 0.0 3e-62 210.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28361.1 - 1.3e-34 119.7 0.0 2.5e-34 118.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28361.1 - 5.6e-05 22.6 0.0 0.00021 20.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGR28361.1 - 0.00043 19.7 0.0 0.00069 19.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGR28361.1 - 0.00055 19.0 0.0 0.00055 19.0 0.0 1.9 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EGR28361.1 - 0.00088 19.3 0.1 0.15 12.0 0.2 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Ribosomal_S30 PF04758.14 EGR28362.1 - 1e-22 80.1 6.5 1.2e-22 79.8 6.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S30 Pribosyltran PF00156.27 EGR28363.1 - 6.1e-12 45.3 0.0 8.2e-12 44.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGR28363.1 - 1.7e-05 24.4 0.0 2.2e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Hemocyanin_M PF00372.19 EGR28363.1 - 0.049 12.8 0.2 0.085 12.0 0.1 1.3 1 1 0 1 1 1 0 Hemocyanin, copper containing domain Pyr_redox_2 PF07992.14 EGR28364.1 - 0.0012 18.1 0.2 0.0023 17.2 0.0 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGR28364.1 - 0.004 16.8 0.2 2.7 7.5 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGR28364.1 - 0.0083 16.7 0.3 0.049 14.2 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EGR28364.1 - 0.013 15.1 0.1 0.028 14.0 0.1 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_7 PF13241.6 EGR28364.1 - 0.052 14.0 0.0 0.086 13.3 0.0 1.4 1 0 0 1 1 1 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 EGR28364.1 - 0.093 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain VWA PF00092.28 EGR28365.1 - 3.5e-17 63.2 0.0 7.2e-17 62.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGR28365.1 - 6.8e-17 62.1 0.1 6.2e-16 59.0 0.0 2.4 2 1 1 3 3 3 1 von Willebrand factor type A domain VWA_3 PF13768.6 EGR28365.1 - 1.5e-06 28.2 0.0 5.8e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 von Willebrand factor type A domain U-box PF04564.15 EGR28365.1 - 1.5e-05 25.0 0.0 3.5e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 U-box domain Methyltransf_5 PF01795.19 EGR28365.1 - 0.086 12.3 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 MraW methylase family Bromodomain PF00439.25 EGR28366.1 - 1.7e-23 82.4 2.1 4.8e-23 81.0 2.1 1.8 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EGR28366.1 - 8.6e-12 45.3 0.1 1.7e-11 44.3 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGR28366.1 - 2.3e-11 43.7 0.4 1.1e-10 41.5 0.3 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGR28366.1 - 1.8e-07 31.4 1.0 3.7e-07 30.5 1.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGR28366.1 - 0.002 18.2 0.5 0.0053 16.8 0.0 2.0 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGR28366.1 - 0.022 14.7 0.0 0.046 13.7 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.7 EGR28366.1 - 0.029 15.0 0.1 0.36 11.5 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF761 PF05553.11 EGR28366.1 - 0.16 11.5 2.6 3.9 7.1 0.3 2.8 2 0 0 2 2 2 0 Cotton fibre expressed protein Pkinase PF00069.25 EGR28367.1 - 1.8e-65 221.0 5.1 1.2e-62 211.7 1.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28367.1 - 4.9e-36 124.3 0.9 6.9e-36 123.9 0.9 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR28367.1 - 4.8e-08 32.3 7.5 6.4e-08 31.9 7.5 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGR28367.1 - 9.5e-07 27.9 0.1 2.2e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGR28367.1 - 5.9e-06 25.8 1.0 1.2e-05 24.8 1.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 EGR28367.1 - 0.0047 17.6 0.5 0.0091 16.7 0.5 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.14 EGR28367.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TTL PF03133.15 EGR28368.1 - 2.4e-37 128.6 20.6 3.2e-37 128.2 20.6 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR28368.1 - 5.7e-07 29.0 6.4 4.1e-05 23.0 0.1 2.7 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR28368.1 - 4.6e-05 22.8 1.4 0.022 14.0 0.0 2.4 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 EGR28368.1 - 0.001 18.7 0.4 1.1 8.8 0.2 2.5 2 0 0 2 2 2 2 RimK-like ATP-grasp domain RUN PF02759.19 EGR28368.1 - 3.3 7.7 7.3 39 4.2 0.1 3.4 2 1 0 2 2 2 0 RUN domain TTL PF03133.15 EGR28369.1 - 2.9e-32 112.0 13.9 4.5e-32 111.3 13.9 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR28369.1 - 0.00047 19.5 1.1 0.0021 17.4 0.1 2.3 2 0 0 2 2 2 1 YheC/D like ATP-grasp Ribosomal_L29 PF00831.23 EGR28369.1 - 0.27 11.2 2.3 0.38 10.8 1.0 2.0 2 0 0 2 2 2 0 Ribosomal L29 protein v110 PF01639.17 EGR28369.1 - 0.46 10.4 4.9 5.7 6.9 0.2 3.2 3 0 0 3 3 3 0 Viral family 110 MASE4 PF17158.4 EGR28370.1 - 0.00022 20.6 1.8 0.00029 20.2 1.8 1.2 1 0 0 1 1 1 1 Membrane-associated sensor, integral membrane domain Claudin_2 PF13903.6 EGR28370.1 - 0.00061 19.6 1.0 0.001 18.9 1.0 1.4 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.6 EGR28370.1 - 0.029 14.6 3.5 0.06 13.6 3.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF2207 PF09972.9 EGR28370.1 - 0.036 12.8 1.1 0.041 12.6 1.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) H_PPase PF03030.16 EGR28370.1 - 0.04 12.5 0.3 0.047 12.3 0.3 1.0 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase Malectin PF11721.8 EGR28371.1 - 3.9e-33 114.9 0.5 6.2e-33 114.2 0.5 1.3 1 0 0 1 1 1 1 Malectin domain DUF3143 PF11341.8 EGR28371.1 - 0.058 13.8 0.3 1.5 9.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3143) LptF_LptG PF03739.14 EGR28371.1 - 0.087 11.7 0.3 0.12 11.2 0.3 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Transgly PF00912.22 EGR28371.1 - 0.12 11.8 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Transglycosylase Pkinase PF00069.25 EGR28372.1 - 9.9e-58 195.6 0.3 1.2e-57 195.3 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28372.1 - 1.3e-25 90.2 0.5 6.3e-25 87.9 0.1 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EGR28372.1 - 0.022 14.1 0.0 0.04 13.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGR28372.1 - 0.023 14.3 0.9 0.047 13.3 0.7 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase B277 PF17623.2 EGR28372.1 - 0.035 13.2 1.3 0.054 12.6 1.3 1.3 1 0 0 1 1 1 0 Domain of unknown function APH PF01636.23 EGR28372.1 - 0.052 13.5 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ras PF00071.22 EGR28373.1 - 1.8e-35 122.0 0.2 2e-35 121.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR28373.1 - 2.2e-19 69.8 0.1 3e-19 69.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR28373.1 - 8.5e-09 35.1 0.0 1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR28373.1 - 0.00019 21.5 0.0 0.00028 20.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGR28373.1 - 0.00057 19.4 0.1 0.003 17.1 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EGR28373.1 - 0.0011 18.6 0.0 0.0024 17.4 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EGR28373.1 - 0.0016 18.2 0.2 0.016 14.9 0.2 2.2 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EGR28373.1 - 0.0032 16.9 0.0 0.0038 16.7 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Zeta_toxin PF06414.12 EGR28373.1 - 0.037 13.3 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 EGR28373.1 - 0.16 12.4 0.0 0.29 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain SPATIAL PF15256.6 EGR28374.1 - 0.029 14.7 0.8 0.029 14.7 0.8 1.0 1 0 0 1 1 1 0 SPATIAL Steroid_dh PF02544.16 EGR28375.1 - 2.7e-20 72.9 11.4 2.7e-20 72.9 11.4 2.4 2 1 0 2 2 2 1 3-oxo-5-alpha-steroid 4-dehydrogenase Clat_adaptor_s PF01217.20 EGR28376.1 - 1.3e-49 167.8 4.1 1.6e-49 167.5 4.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CUB_2 PF02408.20 EGR28377.1 - 0.68 9.7 7.5 0.084 12.6 0.8 2.3 2 1 1 3 3 3 0 CUB-like domain MORN PF02493.20 EGR28379.1 - 7.6e-25 85.3 40.3 2e-08 33.6 1.9 6.1 6 0 0 6 6 6 5 MORN repeat Pkinase_Tyr PF07714.17 EGR28379.1 - 9.1e-15 54.6 0.5 1.6e-14 53.8 0.5 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGR28379.1 - 6.8e-10 38.8 3.3 1.2e-09 37.9 3.3 1.3 1 0 0 1 1 1 1 Protein kinase domain PMSI1 PF15322.6 EGR28380.1 - 2 7.8 5.1 2.1 7.7 5.1 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative WD40 PF00400.32 EGR28381.1 - 3.5e-07 30.8 1.7 0.18 12.7 0.0 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat TPR_12 PF13424.6 EGR28382.1 - 0.076 13.3 1.7 0.89 9.9 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat HHA PF05321.11 EGR28382.1 - 1.7 9.0 7.2 5.6 7.4 0.1 3.7 3 0 0 3 3 3 0 Haemolysin expression modulating protein Pkinase PF00069.25 EGR28383.1 - 8e-45 153.3 0.4 8e-45 153.3 0.4 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28383.1 - 2e-18 66.6 1.0 2.6e-18 66.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EGR28383.1 - 4.6e-08 33.3 0.0 1.4e-05 25.2 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family LEH PF07858.12 EGR28383.1 - 0.0062 16.6 0.0 0.011 15.8 0.0 1.3 1 0 0 1 1 1 1 Limonene-1,2-epoxide hydrolase catalytic domain Pkinase_fungal PF17667.1 EGR28383.1 - 0.018 13.9 1.0 0.31 9.8 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase BolA PF01722.18 EGR28383.1 - 0.089 13.1 0.0 28 5.1 0.0 2.7 2 0 0 2 2 2 0 BolA-like protein Pkinase PF00069.25 EGR28384.1 - 6.4e-06 25.7 0.1 7.6e-06 25.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Rho_N PF07498.12 EGR28384.1 - 0.054 13.4 0.2 0.13 12.2 0.2 1.6 1 0 0 1 1 1 0 Rho termination factor, N-terminal domain Peptidase_M8 PF01457.16 EGR28385.1 - 2.9e-31 108.7 3.9 1.9e-26 92.9 0.1 2.3 1 1 1 2 2 2 2 Leishmanolysin DUF3797 PF12677.7 EGR28385.1 - 0.043 13.7 0.4 0.72 9.8 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) Collagen PF01391.18 EGR28386.1 - 4.6e-08 32.7 36.8 7.6e-06 25.6 16.1 2.4 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) GF_recep_IV PF14843.6 EGR28386.1 - 0.00021 21.1 53.3 0.00044 20.1 31.3 5.2 2 1 4 6 6 6 3 Growth factor receptor domain IV Furin-like_2 PF15913.5 EGR28386.1 - 0.00074 19.6 104.8 0.0026 17.9 15.3 6.4 2 1 4 6 6 6 5 Furin-like repeat, cysteine-rich VSP PF03302.13 EGR28386.1 - 6.2 5.6 118.9 0.2 10.5 9.2 4.0 1 1 2 3 3 3 0 Giardia variant-specific surface protein DcpS_C PF11969.8 EGR28388.1 - 0.0023 18.4 1.5 0.003 18.0 1.5 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Clat_adaptor_s PF01217.20 EGR28389.1 - 4.2e-31 107.8 8.3 4.9e-31 107.6 8.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Herpes_U26 PF07402.11 EGR28389.1 - 0.047 13.3 0.8 0.053 13.1 0.8 1.1 1 0 0 1 1 1 0 Human herpesvirus U26 protein NIF PF03031.18 EGR28390.1 - 1.9e-37 128.4 1.9 2.6e-37 128.0 1.9 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.6 EGR28390.1 - 0.0012 18.9 0.2 0.0012 18.9 0.2 2.1 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase PTH2 PF01981.16 EGR28391.1 - 3.5e-41 140.2 0.0 5.3e-41 139.6 0.0 1.3 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 Cohesin_load PF10345.9 EGR28391.1 - 0.00077 18.0 0.7 0.001 17.6 0.7 1.1 1 0 0 1 1 1 1 Cohesin loading factor DUF494 PF04361.13 EGR28391.1 - 0.075 12.9 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF494) Pkinase PF00069.25 EGR28392.1 - 1.1e-70 238.0 0.6 1.2e-70 237.9 0.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28392.1 - 1.6e-44 152.1 0.1 1.8e-44 151.9 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28392.1 - 1.5e-08 34.3 0.0 4.5e-08 32.7 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EGR28392.1 - 2.9e-05 23.5 1.2 9.9e-05 21.8 1.2 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGR28392.1 - 0.00081 18.4 1.4 0.001 18.1 1.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 EGR28392.1 - 0.0017 18.0 1.2 0.0033 17.0 1.1 1.5 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EGR28392.1 - 0.0049 16.8 0.1 0.02 14.8 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGR28392.1 - 0.035 13.7 1.3 0.056 13.0 1.3 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 EGR28392.1 - 0.092 12.4 0.2 0.19 11.3 0.2 1.6 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 DUF2634 PF10934.8 EGR28392.1 - 0.15 12.2 4.1 0.16 12.1 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2634) SieB PF14163.6 EGR28393.1 - 0.09 12.3 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Super-infection exclusion protein B WD40 PF00400.32 EGR28395.1 - 1.3e-56 187.2 18.9 3.2e-09 37.3 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR28395.1 - 2.7e-13 50.0 3.4 0.0037 17.5 0.0 5.3 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGR28395.1 - 5.1e-10 38.6 2.8 0.053 12.2 0.1 4.4 2 2 2 5 5 5 3 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGR28395.1 - 4.4e-06 25.7 5.2 0.047 12.4 0.6 3.5 1 1 1 3 3 3 2 Nup133 N terminal like WD40_like PF17005.5 EGR28395.1 - 1.2e-05 24.8 5.7 0.0011 18.3 4.5 3.5 1 1 1 2 2 2 1 WD40-like domain Metallophos PF00149.28 EGR28395.1 - 0.03 14.8 1.3 0.9 10.0 0.0 2.6 2 1 0 3 3 3 0 Calcineurin-like phosphoesterase Cytochrom_D1 PF02239.16 EGR28395.1 - 0.038 12.5 0.1 2.6 6.5 0.0 2.2 2 0 0 2 2 2 0 Cytochrome D1 heme domain PALB2_WD40 PF16756.5 EGR28395.1 - 0.044 12.7 1.3 2 7.3 0.1 2.8 1 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain MORN PF02493.20 EGR28396.1 - 4.6e-57 186.6 99.2 1.9e-07 30.6 0.3 14.1 15 0 0 15 15 15 13 MORN repeat Asp PF00026.23 EGR28397.1 - 3.6e-07 29.9 2.0 0.03 13.8 0.0 3.1 3 0 0 3 3 3 3 Eukaryotic aspartyl protease Mtc PF03820.17 EGR28399.1 - 1.8e-68 230.9 0.5 2e-68 230.8 0.5 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier DUF1506 PF07405.11 EGR28399.1 - 0.017 15.3 0.3 0.042 14.0 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1506) G10 PF01125.17 EGR28399.1 - 0.046 13.5 0.3 0.75 9.6 0.1 2.1 2 0 0 2 2 2 0 G10 protein DUF5353 PF17304.2 EGR28399.1 - 0.1 12.4 0.1 0.86 9.4 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5353) BT1 PF03092.16 EGR28400.1 - 1.1e-42 146.0 18.0 8.8e-39 133.1 11.2 2.1 1 1 0 2 2 2 2 BT1 family MFS_1 PF07690.16 EGR28400.1 - 3.3e-14 52.6 29.1 9.7e-10 37.9 15.7 1.9 1 1 1 2 2 2 2 Major Facilitator Superfamily LVIVD PF08309.11 EGR28401.1 - 0.0098 15.2 0.1 0.088 12.1 0.1 2.5 2 0 0 2 2 2 1 LVIVD repeat Acyltransferase PF01553.21 EGR28402.1 - 4.2e-17 62.0 0.1 2.3e-08 33.7 0.1 2.5 2 0 0 2 2 2 2 Acyltransferase Na_H_Exchanger PF00999.21 EGR28403.1 - 8.6e-48 163.0 33.5 8.6e-48 163.0 33.5 1.6 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family PhoQ_Sensor PF08918.10 EGR28403.1 - 0.03 14.2 3.3 0.093 12.6 3.3 1.8 1 0 0 1 1 1 0 PhoQ Sensor cNMP_binding PF00027.29 EGR28404.1 - 2e-39 133.5 0.0 7.3e-20 70.8 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Beach PF02138.18 EGR28407.1 - 4e-89 298.7 2.7 5.7e-89 298.2 2.7 1.2 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 EGR28407.1 - 0.00049 20.9 0.0 0.049 14.5 0.0 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EGR28407.1 - 0.0015 17.4 1.3 0.0015 17.4 1.3 2.6 2 1 1 3 3 3 2 Nup133 N terminal like ANAPC4_WD40 PF12894.7 EGR28407.1 - 0.045 14.0 0.6 11 6.4 0.1 2.5 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain ABC_tran PF00005.27 EGR28408.1 - 1.7e-38 132.3 8.8 7.5e-28 97.8 0.0 3.4 4 0 0 4 4 4 2 ABC transporter ABC_membrane PF00664.23 EGR28408.1 - 1.2e-22 80.9 32.4 1.9e-22 80.2 32.4 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region RsgA_GTPase PF03193.16 EGR28408.1 - 0.00031 20.7 0.0 0.001 19.0 0.0 1.9 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EGR28408.1 - 0.025 14.7 0.4 0.063 13.4 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA PF00004.29 EGR28408.1 - 0.039 14.4 0.0 0.19 12.2 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGR28408.1 - 0.049 13.9 0.0 0.22 11.8 0.0 2.1 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGR28408.1 - 0.074 12.8 0.3 0.43 10.3 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein SMC_N PF02463.19 EGR28408.1 - 0.38 10.2 18.9 1.6 8.1 0.1 3.8 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain ResIII PF04851.15 EGR28408.1 - 3.6 7.6 23.8 0.15 12.0 2.6 4.1 2 1 2 4 4 4 0 Type III restriction enzyme, res subunit Polo_box_3 PF18544.1 EGR28409.1 - 0.089 13.4 0.4 0.11 13.2 0.4 1.1 1 0 0 1 1 1 0 Polo box domain Piwi PF02171.17 EGR28410.1 - 6.6e-64 216.0 4.7 6.6e-64 216.0 4.7 1.5 2 0 0 2 2 2 1 Piwi domain PAZ PF02170.22 EGR28410.1 - 5.4e-14 52.2 2.1 5.4e-14 52.2 2.1 2.0 2 0 0 2 2 2 1 PAZ domain ArgoMid PF16487.5 EGR28410.1 - 0.071 13.4 0.1 7.5 6.9 0.0 3.0 2 0 0 2 2 2 0 Mid domain of argonaute WD40 PF00400.32 EGR28411.1 - 8.4e-11 42.3 0.0 0.11 13.5 0.0 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR28411.1 - 2.7e-08 34.0 0.0 3.4e-05 24.0 0.0 3.1 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain HSP70 PF00012.20 EGR28412.1 - 0.4 8.8 0.0 0.4 8.8 0.0 5.6 2 1 3 5 5 5 0 Hsp70 protein Arrestin_C PF02752.22 EGR28413.1 - 3.3e-06 27.6 6.7 8.9e-05 23.0 0.9 2.7 2 1 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EGR28413.1 - 2.8e-05 24.2 0.2 0.024 14.7 0.1 3.0 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain Cyclin_N PF00134.23 EGR28414.1 - 1.3e-11 44.3 0.1 1.3e-11 44.3 0.1 4.3 3 2 1 4 4 4 2 Cyclin, N-terminal domain Pkinase PF00069.25 EGR28415.1 - 3.9e-42 144.4 0.2 5.7e-42 143.9 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28415.1 - 3.7e-19 69.0 0.1 1.1e-18 67.5 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR28415.1 - 0.0023 16.9 0.2 0.0054 15.7 0.0 1.6 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EGR28415.1 - 0.0047 16.9 0.0 0.008 16.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGR28415.1 - 0.0068 15.7 0.3 0.013 14.9 0.0 1.6 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGR28415.1 - 0.0075 15.6 0.1 0.014 14.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGR28415.1 - 0.046 13.3 0.6 0.38 10.3 0.0 2.1 2 0 0 2 2 2 0 Choline/ethanolamine kinase RNA_pol_A_bac PF01000.26 EGR28416.1 - 1.3e-27 96.4 0.7 1.3e-27 96.4 0.7 2.3 3 0 0 3 3 3 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EGR28416.1 - 1.1e-11 44.0 0.0 1.4e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain ETF_QO PF05187.13 EGR28416.1 - 0.083 13.0 0.4 0.083 13.0 0.4 2.0 2 1 0 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_9 PF13187.6 EGR28416.1 - 0.12 12.6 2.7 0.29 11.3 2.7 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain ABC_tran PF00005.27 EGR28417.1 - 1.3e-25 90.6 0.1 2e-25 89.9 0.1 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGR28417.1 - 0.00092 19.1 1.3 0.012 15.4 0.0 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGR28417.1 - 0.0073 15.8 1.1 0.12 11.8 0.1 2.1 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGR28417.1 - 0.012 15.5 1.1 0.035 14.0 0.2 2.0 2 0 0 2 2 2 0 RsgA GTPase SbcCD_C PF13558.6 EGR28417.1 - 0.012 15.8 0.2 0.29 11.4 0.2 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Rad17 PF03215.15 EGR28417.1 - 0.035 14.0 0.1 0.052 13.5 0.1 1.5 1 1 0 1 1 1 0 Rad17 P-loop domain T6SS_VipA PF05591.12 EGR28417.1 - 0.037 13.8 0.5 0.059 13.2 0.5 1.2 1 0 0 1 1 1 0 Type VI secretion system, VipA, VC_A0107 or Hcp2 AAA_22 PF13401.6 EGR28417.1 - 0.072 13.4 0.7 0.32 11.3 0.7 2.0 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGR28417.1 - 0.076 13.4 0.0 0.18 12.2 0.0 1.7 1 1 0 1 1 1 0 RNA helicase AAA_16 PF13191.6 EGR28417.1 - 0.082 13.3 0.0 0.18 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EGR28417.1 - 0.089 12.6 0.2 0.19 11.5 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain UQ_con PF00179.26 EGR28418.1 - 8.3e-53 177.8 0.0 9.3e-53 177.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGR28418.1 - 0.0043 17.3 0.1 0.0045 17.3 0.1 1.3 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EGR28418.1 - 0.018 14.8 0.0 0.023 14.4 0.0 1.1 1 0 0 1 1 1 0 Prokaryotic E2 family B Cytochrom_B561 PF03188.16 EGR28419.1 - 1.8e-06 28.1 8.5 3.3e-06 27.3 8.5 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 Cyt-b5 PF00173.28 EGR28419.1 - 0.014 15.5 0.1 0.033 14.3 0.0 1.6 2 0 0 2 2 2 0 Cytochrome b5-like Heme/Steroid binding domain DUF2627 PF11118.8 EGR28419.1 - 0.31 11.6 14.7 1.1 9.9 6.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2627) Ni_hydr_CYTB PF01292.20 EGR28419.1 - 0.57 9.8 12.3 1.2 8.8 12.2 1.6 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 cNMP_binding PF00027.29 EGR28420.1 - 6.6e-08 32.5 0.1 8.4e-07 29.0 0.1 2.4 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Phenyl_P_gamma PF09662.10 EGR28420.1 - 0.16 12.1 2.1 0.25 11.5 0.1 2.4 2 0 0 2 2 2 0 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) UVR PF02151.19 EGR28421.1 - 8.1e-13 47.7 16.9 1.3e-07 31.2 5.6 2.9 2 0 0 2 2 2 2 UvrB/uvrC motif zf_UBZ PF18439.1 EGR28421.1 - 0.0058 16.2 0.7 0.37 10.4 0.3 3.0 2 0 0 2 2 2 1 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 EGR28421.1 - 1.5 9.2 9.9 5 7.5 5.5 3.1 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-ribbon_3 PF13248.6 EGR28421.1 - 5.8 6.5 6.5 12 5.4 0.1 3.5 3 0 0 3 3 3 0 zinc-ribbon domain TPR_2 PF07719.17 EGR28423.1 - 1.7e-28 96.3 9.3 0.16 12.1 0.0 11.8 12 0 0 12 12 12 7 Tetratricopeptide repeat TPR_1 PF00515.28 EGR28423.1 - 7.3e-21 73.1 22.9 0.0037 17.0 0.0 12.1 12 0 0 12 12 12 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGR28423.1 - 3.6e-15 56.0 11.7 2e-05 24.8 0.0 8.2 6 5 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGR28423.1 - 5.9e-15 54.1 0.2 0.058 13.4 0.0 7.4 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGR28423.1 - 1.5e-13 51.0 1.0 0.77 10.3 0.0 7.5 6 2 2 9 9 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGR28423.1 - 2.8e-13 49.3 3.9 0.05 13.3 0.0 7.1 5 2 2 7 7 7 4 TPR repeat ANAPC3 PF12895.7 EGR28423.1 - 1.6e-12 47.4 14.5 2.3e-05 24.5 1.2 6.2 5 3 1 6 6 5 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EGR28423.1 - 1.1e-10 41.4 0.0 0.92 10.5 0.0 7.3 5 2 3 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGR28423.1 - 2.9e-10 39.5 25.1 0.21 11.9 0.0 11.3 13 0 0 13 13 12 4 Tetratricopeptide repeat TPR_6 PF13174.6 EGR28423.1 - 1.1e-09 38.2 17.8 1.3 9.8 0.0 10.4 12 0 0 12 12 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGR28423.1 - 1.9e-08 34.8 0.0 3.3 8.4 0.0 6.3 5 2 1 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGR28423.1 - 0.00015 21.5 2.6 15 5.6 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGR28423.1 - 0.00081 19.6 3.2 40 4.9 0.2 7.2 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_20 PF14561.6 EGR28423.1 - 0.035 14.4 4.5 0.28 11.5 0.1 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ATP13 PF12921.7 EGR28423.1 - 0.078 12.8 1.0 3.9 7.4 0.0 3.5 4 0 0 4 4 4 0 Mitochondrial ATPase expression BTAD PF03704.17 EGR28423.1 - 0.11 13.0 1.4 6 7.3 0.0 4.0 6 0 0 6 6 5 0 Bacterial transcriptional activator domain PPR PF01535.20 EGR28423.1 - 1.2 9.6 8.5 28 5.2 0.0 5.5 6 0 0 6 6 5 0 PPR repeat Hormone_1 PF00103.20 EGR28423.1 - 4.2 7.1 12.0 2.5 7.8 0.9 3.5 3 0 0 3 3 3 0 Somatotropin hormone family Guanylate_cyc PF00211.20 EGR28424.1 - 3e-82 274.7 2.4 2.1e-40 138.3 0.8 2.1 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain PRESAN PF09687.10 EGR28424.1 - 0.032 14.8 0.2 0.032 14.8 0.2 3.3 4 0 0 4 4 4 0 Plasmodium RESA N-terminal NYD-SP28_assoc PF14775.6 EGR28425.1 - 0.00011 22.3 6.7 0.00011 22.3 6.7 4.2 4 0 0 4 4 4 1 Sperm tail C-terminal domain NYD-SP28 PF14772.6 EGR28425.1 - 0.00029 20.8 11.9 0.00029 20.8 11.9 5.5 3 1 3 6 6 6 1 Sperm tail WD40 PF00400.32 EGR28426.1 - 3.2e-07 30.9 2.7 0.025 15.4 0.1 5.3 6 0 0 6 6 6 2 WD domain, G-beta repeat UDPGP PF01704.18 EGR28427.1 - 8.8e-15 54.3 0.1 1.2e-14 53.9 0.1 1.3 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF5344 PF17279.2 EGR28427.1 - 0.054 14.1 1.5 0.15 12.7 0.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5344) ApoLp-III PF07464.11 EGR28427.1 - 0.52 10.4 3.4 0.31 11.1 0.7 2.0 3 0 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) DUF4533 PF15047.6 EGR28429.1 - 0.032 13.8 3.9 0.034 13.7 3.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4533) EF-hand_1 PF00036.32 EGR28430.1 - 4.5e-35 116.6 9.6 1.1e-05 24.7 0.2 7.9 7 0 0 7 7 7 6 EF hand EF-hand_6 PF13405.6 EGR28430.1 - 2.3e-34 114.4 12.9 0.00012 21.7 0.1 8.0 8 0 0 8 8 8 6 EF-hand domain EF-hand_7 PF13499.6 EGR28430.1 - 7.4e-33 112.8 16.2 2.5e-10 40.6 2.0 5.0 4 1 1 5 5 5 5 EF-hand domain pair EF-hand_8 PF13833.6 EGR28430.1 - 2.7e-24 84.8 7.0 3e-06 27.0 0.1 6.1 5 1 1 6 6 5 5 EF-hand domain pair EF-hand_5 PF13202.6 EGR28430.1 - 3.2e-15 54.8 14.0 0.0047 16.4 0.2 7.0 7 0 0 7 7 7 4 EF hand RST PF12174.8 EGR28430.1 - 2.7e-09 36.8 1.4 0.0035 17.2 0.0 3.5 3 0 0 3 3 3 2 RCD1-SRO-TAF4 (RST) plant domain EF-hand_9 PF14658.6 EGR28430.1 - 1.7e-07 31.5 0.9 0.038 14.3 0.0 4.5 5 0 0 5 5 5 2 EF-hand domain Caleosin PF05042.13 EGR28430.1 - 0.00025 21.0 5.9 0.89 9.5 0.0 4.9 3 2 2 5 5 5 1 Caleosin related protein DUF5580 PF17743.1 EGR28430.1 - 0.00048 18.8 1.3 2.2 6.7 0.0 3.1 2 1 1 3 3 3 2 Family of unknown function (DUF5580) TerB PF05099.13 EGR28430.1 - 0.0024 17.8 1.6 1.1 9.3 0.1 3.4 3 0 0 3 3 3 1 Tellurite resistance protein TerB EF-hand_11 PF08976.11 EGR28430.1 - 0.011 16.6 5.2 5 8.0 0.1 3.9 3 1 1 4 4 4 0 EF-hand domain Acetyltransf_11 PF13720.6 EGR28430.1 - 0.024 15.1 1.8 9.3 6.8 0.0 3.5 2 1 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 EF-hand_4 PF12763.7 EGR28430.1 - 0.041 13.8 2.7 28 4.7 0.0 4.0 3 1 1 4 4 4 0 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EGR28430.1 - 0.082 12.8 7.4 3.8 7.4 0.2 4.3 4 0 0 4 4 4 0 EF hand ORC4_C PF14629.6 EGR28430.1 - 0.2 11.0 3.0 0.39 10.0 0.6 2.6 3 1 0 3 3 3 0 Origin recognition complex (ORC) subunit 4 C-terminus SPARC_Ca_bdg PF10591.9 EGR28430.1 - 0.28 11.5 9.5 14 6.0 0.2 4.6 4 1 1 5 5 4 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 EGR28430.1 - 1.4 9.3 8.4 22 5.5 0.0 4.7 5 1 0 5 5 5 0 EF-hand domain Gp-FAR-1 PF05823.12 EGR28430.1 - 2.7 8.4 8.5 0.49 10.7 2.2 2.8 2 1 1 3 3 3 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) WD40 PF00400.32 EGR28431.1 - 3.2e-25 87.9 10.3 8.4e-06 26.4 0.1 6.4 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR28431.1 - 9.4e-05 22.6 2.4 0.004 17.4 0.2 3.5 2 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EGR28431.1 - 0.0015 17.2 0.1 0.0032 16.1 0.1 1.5 1 0 0 1 1 1 1 Cytochrome D1 heme domain DUF4047 PF13256.6 EGR28431.1 - 0.13 12.4 4.5 0.068 13.4 1.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) SNRNP27 PF08648.12 EGR28432.1 - 4.1e-21 74.8 1.6 5.8e-21 74.3 1.6 1.2 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins L31 PF09784.9 EGR28432.1 - 0.053 13.9 0.9 0.057 13.9 0.9 1.1 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 Pkinase PF00069.25 EGR28433.1 - 1.6e-67 227.7 1.9 1.8e-67 227.5 1.9 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28433.1 - 2.2e-33 115.7 0.4 2.9e-33 115.3 0.4 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR28433.1 - 0.012 14.9 0.1 0.019 14.3 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA-synt_1b PF00579.25 EGR28434.1 - 6.1e-56 189.9 9.0 8.6e-41 140.2 4.5 2.7 2 1 1 3 3 3 2 tRNA synthetases class I (W and Y) RasGEF PF00617.19 EGR28434.1 - 0.011 16.0 0.7 0.031 14.5 0.7 1.8 1 0 0 1 1 1 0 RasGEF domain UQ_con PF00179.26 EGR28435.1 - 7e-13 48.4 3.0 7e-13 48.4 3.0 1.9 3 0 0 3 3 3 1 Ubiquitin-conjugating enzyme Kelch_5 PF13854.6 EGR28436.1 - 6.4e-30 102.6 5.6 5.2e-10 39.1 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 EGR28436.1 - 2.9e-27 94.4 0.0 1.3e-09 38.1 0.0 5.3 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EGR28436.1 - 5.6e-27 93.1 5.6 9e-07 29.0 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_4 PF13418.6 EGR28436.1 - 2.5e-26 91.4 4.4 2.4e-07 30.6 0.0 5.2 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 EGR28436.1 - 8.5e-20 70.1 3.1 1e-05 25.0 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 EGR28436.1 - 4.4e-19 67.6 6.7 2.2e-06 27.4 0.0 5.4 5 0 0 5 5 5 4 Kelch motif EFTUD2 PF16004.5 EGR28436.1 - 0.084 13.5 3.4 0.2 12.3 3.4 1.6 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Tfb4 PF03850.14 EGR28436.1 - 0.11 12.0 3.7 0.16 11.5 3.7 1.2 1 0 0 1 1 1 0 Transcription factor Tfb4 PMI_typeI PF01238.21 EGR28437.1 - 3.8e-56 190.9 6.4 4.7e-56 190.6 6.4 1.1 1 0 0 1 1 1 1 Phosphomannose isomerase type I DSX_dimer PF08828.10 EGR28437.1 - 0.97 9.2 3.7 7 6.4 0.4 2.5 2 0 0 2 2 2 0 Doublesex dimerisation domain STI1 PF17830.1 EGR28437.1 - 4 7.5 7.3 0.8 9.7 0.7 2.8 3 0 0 3 3 3 0 STI1 domain Sel1 PF08238.12 EGR28438.1 - 6.5e-10 39.4 10.7 0.33 11.7 0.4 5.0 4 1 0 4 4 4 4 Sel1 repeat Asp PF00026.23 EGR28439.1 - 1.1e-11 44.7 1.7 2e-11 43.9 1.7 1.4 1 0 0 1 1 1 1 Eukaryotic aspartyl protease gag-asp_proteas PF13975.6 EGR28439.1 - 0.14 12.8 0.0 2.2 8.9 0.0 2.4 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease WSD PF15613.6 EGR28439.1 - 0.25 11.9 2.6 0.27 11.7 0.9 2.0 2 0 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DUF4430 PF14478.6 EGR28440.1 - 0.032 14.8 1.2 0.11 13.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4430) ZYG-11_interact PF05884.12 EGR28440.1 - 0.22 10.9 5.9 0.16 11.3 4.9 1.3 1 1 0 1 1 1 0 Interactor of ZYG-11 Raptor_N PF14538.6 EGR28440.1 - 0.41 10.6 6.3 0.55 10.2 6.0 1.4 1 1 0 1 1 1 0 Raptor N-terminal CASPase like domain Pkinase PF00069.25 EGR28442.1 - 2.3e-66 223.8 1.8 4.2e-66 223.0 1.8 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28442.1 - 1e-44 152.8 0.2 1.7e-44 152.0 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EGR28442.1 - 8.4e-06 25.5 0.9 3.3e-05 23.6 0.9 1.9 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EGR28442.1 - 0.0003 19.7 0.0 0.0009 18.1 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase DUF1653 PF07866.11 EGR28442.1 - 0.097 13.0 0.3 0.37 11.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1653) APH PF01636.23 EGR28442.1 - 0.11 12.3 0.0 0.27 11.1 0.1 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF2207 PF09972.9 EGR28442.1 - 0.33 9.7 11.9 0.51 9.0 11.9 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Med17 PF10156.9 EGR28443.1 - 0.062 12.0 10.5 0.06 12.1 10.5 1.1 1 0 0 1 1 1 0 Subunit 17 of Mediator complex Sporozoite_P67 PF05642.11 EGR28443.1 - 0.31 9.1 6.6 0.29 9.2 6.6 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Na_trans_assoc PF06512.13 EGR28443.1 - 0.31 11.3 11.2 0.31 11.3 11.2 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated Voldacs PF03517.13 EGR28443.1 - 0.32 11.1 10.2 0.36 11.0 10.2 1.0 1 0 0 1 1 1 0 Regulator of volume decrease after cellular swelling NOA36 PF06524.12 EGR28443.1 - 0.44 9.8 11.4 0.46 9.8 11.4 1.0 1 0 0 1 1 1 0 NOA36 protein DNA_pol_phi PF04931.13 EGR28443.1 - 0.52 8.3 10.4 0.53 8.3 10.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi PI3K_1B_p101 PF10486.9 EGR28443.1 - 3.3 5.4 8.7 2.9 5.6 8.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CENP-B_dimeris PF09026.10 EGR28443.1 - 3.9 7.9 16.4 2.5 8.5 14.9 1.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain EF-hand_1 PF00036.32 EGR28444.1 - 2.1e-19 67.6 16.6 3e-07 29.5 0.3 3.7 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EGR28444.1 - 6.6e-18 64.9 9.3 1.9e-10 41.0 2.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR28444.1 - 2.3e-14 52.0 11.5 2.7e-07 30.0 0.3 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.6 EGR28444.1 - 5.6e-12 45.3 13.9 1.4e-05 24.8 1.0 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 EGR28444.1 - 1.1e-08 35.2 0.2 1.6e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGR28444.1 - 2.5e-05 23.5 0.7 2.5e-05 23.5 0.7 3.7 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.7 EGR28444.1 - 5.2e-05 23.1 9.9 0.046 13.7 2.6 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_14 PF17959.1 EGR28444.1 - 0.00044 20.5 5.0 0.0029 17.9 4.7 2.3 1 1 0 1 1 1 1 EF-hand domain Caleosin PF05042.13 EGR28444.1 - 0.0027 17.6 5.5 0.59 10.1 0.6 3.0 1 1 2 3 3 3 2 Caleosin related protein bPH_3 PF14470.6 EGR28444.1 - 0.0037 17.6 2.5 0.0037 17.6 2.5 1.9 2 0 0 2 2 2 1 Bacterial PH domain XPG_I_2 PF12813.7 EGR28444.1 - 0.074 12.5 1.0 0.17 11.3 0.6 1.7 1 1 1 2 2 2 0 XPG domain containing Syja_N PF02383.18 EGR28446.1 - 1.2e-53 182.5 3.6 1.6e-53 182.1 3.6 1.1 1 0 0 1 1 1 1 SacI homology domain DHHC PF01529.20 EGR28447.1 - 3.5e-19 69.2 13.9 3.6e-19 69.2 13.9 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase IGFBP PF00219.18 EGR28447.1 - 0.3 11.8 9.5 0.62 10.8 9.5 1.6 1 1 0 1 1 1 0 Insulin-like growth factor binding protein MRC1 PF09444.10 EGR28448.1 - 0.00062 20.3 24.6 0.001 19.6 24.6 1.3 1 1 0 1 1 1 1 MRC1-like domain Ion_trans PF00520.31 EGR28449.1 - 5.8e-98 327.0 67.7 1e-47 162.5 29.0 3.1 3 0 0 3 3 3 3 Ion transport protein PKD_channel PF08016.12 EGR28449.1 - 1.8e-10 40.1 61.4 4.6e-08 32.1 13.0 6.2 4 2 1 6 6 6 5 Polycystin cation channel RAMP4 PF06624.12 EGR28449.1 - 4.5 7.4 12.3 1.2 9.3 0.5 3.0 2 0 0 2 2 2 0 Ribosome associated membrane protein RAMP4 Ion_trans PF00520.31 EGR28450.1 - 2.2e-42 145.0 25.7 2.2e-42 145.0 25.7 2.5 2 1 0 2 2 2 1 Ion transport protein DUF4139 PF13598.6 EGR28450.1 - 1.7 8.3 6.9 2.7 7.6 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4139) 2OG-FeII_Oxy_3 PF13640.6 EGR28451.1 - 1.9e-05 25.5 0.0 5.9e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_12 PF13424.6 EGR28451.1 - 0.0024 18.1 5.8 0.022 15.0 3.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGR28451.1 - 0.0056 16.1 4.4 0.013 15.0 0.3 3.1 3 0 0 3 3 3 1 SHNi-TPR TPR_8 PF13181.6 EGR28451.1 - 0.094 13.0 4.3 4.8 7.6 0.3 4.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGR28451.1 - 3.5 8.0 8.6 4.8 7.5 0.5 4.1 3 1 0 3 3 3 0 Tetratricopeptide repeat EF-hand_7 PF13499.6 EGR28452.1 - 0.0036 17.7 0.4 0.018 15.5 0.4 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGR28452.1 - 0.035 13.7 0.5 0.17 11.5 0.0 2.4 3 0 0 3 3 3 0 EF hand EF-hand_6 PF13405.6 EGR28452.1 - 0.12 12.4 0.8 0.99 9.5 0.0 2.8 4 0 0 4 4 4 0 EF-hand domain ABC1 PF03109.16 EGR28453.1 - 3.9e-34 117.4 0.2 1.1e-33 115.9 0.1 1.9 2 0 0 2 2 2 1 ABC1 family Reovirus_Mu2 PF07781.11 EGR28453.1 - 0.15 10.4 0.0 0.35 9.2 0.0 1.5 2 0 0 2 2 2 0 Reovirus minor core protein Mu-2 APH PF01636.23 EGR28453.1 - 0.19 11.6 0.0 0.76 9.6 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Sugar_tr PF00083.24 EGR28454.1 - 6.4e-14 51.7 15.1 8.1e-14 51.3 15.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Phage_holin_6_1 PF09682.10 EGR28454.1 - 0.011 16.1 0.2 0.031 14.7 0.1 1.8 2 0 0 2 2 2 0 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF1512 PF07431.12 EGR28454.1 - 0.12 11.3 0.0 0.53 9.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1512) Insulin_TMD PF17870.1 EGR28454.1 - 2.7 8.2 7.3 7.2 6.8 0.8 2.8 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment UCH PF00443.29 EGR28455.1 - 7.6e-43 146.9 17.9 2.5e-42 145.1 17.9 2.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR28455.1 - 1.8e-21 77.1 23.9 1.8e-21 77.1 23.9 3.3 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase SGS PF05002.15 EGR28455.1 - 2.5 8.3 5.2 1.2 9.3 1.4 2.5 2 0 0 2 2 2 0 SGS domain PITH PF06201.13 EGR28456.1 - 6e-26 91.5 4.2 7.8e-26 91.1 4.2 1.2 1 0 0 1 1 1 1 PITH domain Aminotran_5 PF00266.19 EGR28457.1 - 6.6e-24 84.6 0.0 8.3e-24 84.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGR28457.1 - 8e-07 27.9 0.1 1.1e-06 27.4 0.1 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 EGR28457.1 - 3.7e-05 22.4 0.7 5.5e-05 21.9 0.7 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.21 EGR28457.1 - 0.0044 16.2 0.0 0.0072 15.5 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II GDC-P PF02347.16 EGR28457.1 - 0.12 11.2 0.0 0.16 10.8 0.0 1.1 1 0 0 1 1 1 0 Glycine cleavage system P-protein Pkinase PF00069.25 EGR28458.1 - 1.7e-27 96.4 0.3 1.7e-27 96.4 0.3 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28458.1 - 1.2e-17 64.0 3.4 1.7e-17 63.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR28458.1 - 1.1e-06 27.7 0.0 1.1e-06 27.7 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase FtsL PF04999.13 EGR28458.1 - 3 7.9 6.0 7.5 6.6 6.0 1.6 1 0 0 1 1 1 0 Cell division protein FtsL Ion_trans PF00520.31 EGR28459.1 - 8.1e-15 54.7 20.2 8.1e-15 54.7 20.2 2.1 2 1 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 EGR28459.1 - 2.2e-13 50.0 2.7 2.2e-13 50.0 2.7 2.8 3 1 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 EGR28459.1 - 0.00014 21.9 0.0 0.00025 21.0 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Cmc1 PF08583.10 EGR28460.1 - 7.3e-05 22.7 1.3 7.3e-05 22.7 1.3 1.5 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF3578 PF12102.8 EGR28460.1 - 0.0073 15.9 0.6 0.0086 15.7 0.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3578) Arm PF00514.23 EGR28461.1 - 2.7e-34 116.1 16.0 6.3e-10 38.8 0.2 7.3 7 0 0 7 7 7 5 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EGR28461.1 - 5.2e-18 63.6 7.1 0.024 14.9 0.0 7.7 8 0 0 8 8 7 5 HEAT repeat HEAT_2 PF13646.6 EGR28461.1 - 1.6e-15 57.2 14.5 0.00094 19.5 0.1 5.4 3 2 2 5 5 5 4 HEAT repeats HEAT_EZ PF13513.6 EGR28461.1 - 4.2e-12 46.3 15.5 1.5e-05 25.3 0.4 6.1 4 2 4 8 8 8 5 HEAT-like repeat Cnd1 PF12717.7 EGR28461.1 - 2.4e-10 40.7 2.9 0.038 14.0 0.2 4.1 1 1 3 5 5 5 4 non-SMC mitotic condensation complex subunit 1 DNA_alkylation PF08713.11 EGR28461.1 - 1.6e-06 28.0 1.2 0.85 9.3 0.0 4.3 3 1 1 4 4 4 2 DNA alkylation repair enzyme RICTOR_N PF14664.6 EGR28461.1 - 0.0011 18.1 3.7 0.0027 16.8 0.5 2.8 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term Atx10homo_assoc PF09759.9 EGR28461.1 - 0.0015 18.5 1.2 2.7 8.1 0.1 4.5 3 1 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 EGR28461.1 - 0.0034 16.9 0.9 3.5 7.0 0.0 3.6 3 1 1 4 4 4 2 Armadillo-like HEAT_PBS PF03130.16 EGR28461.1 - 0.0059 17.2 14.3 0.42 11.4 0.1 6.0 7 0 0 7 7 6 2 PBS lyase HEAT-like repeat CLASP_N PF12348.8 EGR28461.1 - 0.0089 15.6 1.6 0.034 13.7 0.4 2.3 2 0 0 2 2 2 1 CLASP N terminal Vac14_Fab1_bd PF12755.7 EGR28461.1 - 0.01 16.4 0.8 1.5 9.5 0.1 3.3 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EGR28461.1 - 0.013 14.1 7.8 2 6.9 0.7 3.8 2 2 2 4 4 4 0 Adaptin N terminal region CHASE6_C PF17150.4 EGR28461.1 - 0.018 15.7 2.1 7.5 7.3 0.1 4.3 4 1 0 4 4 3 0 C-terminal domain of two-partite extracellular sensor domain Mo25 PF08569.11 EGR28461.1 - 0.025 14.0 0.3 11 5.2 0.1 3.0 1 1 0 2 2 2 0 Mo25-like Proteasom_PSMB PF10508.9 EGR28461.1 - 0.056 12.0 6.2 0.2 10.1 0.2 3.3 1 1 3 4 4 4 0 Proteasome non-ATPase 26S subunit DUF3361 PF11841.8 EGR28461.1 - 0.29 11.0 2.4 27 4.6 0.7 3.6 3 1 1 4 4 4 0 Domain of unknown function (DUF3361) Ras PF00071.22 EGR28462.1 - 7.3e-53 178.5 0.8 1.6e-52 177.3 0.8 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR28462.1 - 5.7e-35 120.1 0.1 5.7e-35 120.1 0.1 2.6 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase TLD PF07534.16 EGR28462.1 - 3e-17 63.1 2.9 7.8e-17 61.8 2.9 1.7 1 0 0 1 1 1 1 TLD Arf PF00025.21 EGR28462.1 - 6.1e-14 51.9 0.3 1.3e-13 50.8 0.3 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR28462.1 - 7.1e-06 26.1 0.0 1.8e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGR28462.1 - 4.9e-05 23.0 0.1 0.00057 19.5 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGR28462.1 - 0.00016 21.2 0.4 0.00032 20.1 0.2 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGR28462.1 - 0.0017 18.3 0.3 0.12 12.2 0.2 2.7 2 1 0 2 2 2 1 RsgA GTPase MeaB PF03308.16 EGR28462.1 - 0.11 11.5 0.8 0.82 8.6 0.7 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB MYCBPAP PF14646.6 EGR28464.1 - 2.1e-20 73.1 6.7 2.1e-20 73.1 6.7 1.7 2 0 0 2 2 2 1 MYCBP-associated protein family Glyco_hydro_59M PF17387.2 EGR28464.1 - 0.029 14.5 0.4 1.4 9.1 0.0 2.6 2 0 0 2 2 2 0 Glycosyl hydrolase family 59 central domain PGK PF00162.19 EGR28466.1 - 7.3e-24 84.4 1.4 1e-22 80.6 0.2 2.0 2 0 0 2 2 2 2 Phosphoglycerate kinase Glutaredoxin2_C PF04399.13 EGR28466.1 - 0.21 11.4 4.9 5.9 6.7 0.3 2.9 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain DUF778 PF05608.12 EGR28466.1 - 3.4 8.0 4.7 6.4 7.1 4.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF778) Pkinase PF00069.25 EGR28467.1 - 3.5e-72 242.9 0.1 5.4e-72 242.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28467.1 - 6.1e-41 140.4 0.0 8.4e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28467.1 - 2.7e-07 30.2 0.0 1.3e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR28467.1 - 9.3e-06 24.7 0.0 1.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EGR28467.1 - 0.011 15.4 0.1 0.036 13.7 0.1 2.1 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGR28467.1 - 0.013 15.4 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGR28467.1 - 0.11 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FA_hydroxylase PF04116.13 EGR28468.1 - 2.9e-13 50.3 7.7 2.9e-13 50.3 7.7 1.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Peptidase_M16_M PF16187.5 EGR28469.1 - 1.5e-38 132.7 9.5 1.5e-38 132.7 9.5 2.5 3 0 0 3 3 3 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EGR28469.1 - 4.1e-35 121.0 0.2 4.1e-35 121.0 0.2 2.5 2 1 1 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGR28469.1 - 1.5e-21 77.2 1.8 5.3e-21 75.5 0.7 2.4 2 0 0 2 2 2 1 Peptidase M16 inactive domain DUF1573 PF07610.11 EGR28470.1 - 0.0086 16.1 0.2 0.51 10.4 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1573) ASH PF15780.5 EGR28470.1 - 0.062 13.5 0.1 7.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 EGR28470.1 - 0.1 12.9 0.2 0.99 9.7 0.0 2.3 2 0 0 2 2 2 0 Transmembrane protein 131-like Motile_Sperm PF00635.26 EGR28470.1 - 0.15 11.9 3.5 4.4 7.2 0.1 3.1 3 0 0 3 3 3 0 MSP (Major sperm protein) domain Pkinase PF00069.25 EGR28471.1 - 3.9e-60 203.5 0.6 4.6e-60 203.2 0.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28471.1 - 5.1e-40 137.4 0.1 6.4e-40 137.1 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28471.1 - 1.3e-07 31.2 0.1 3.1e-07 30.0 0.1 1.7 1 1 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGR28471.1 - 2.2e-07 30.2 2.0 5.6e-07 28.8 2.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGR28471.1 - 0.0002 20.3 0.0 0.00033 19.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EGR28471.1 - 0.00078 19.1 2.2 0.14 11.8 0.3 2.2 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EGR28471.1 - 0.0017 18.0 0.9 0.0036 16.9 0.9 1.5 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 EGR28471.1 - 0.12 12.2 0.0 6.3 6.7 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGR28471.1 - 0.14 11.5 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Mononeg_mRNAcap PF14318.6 EGR28472.1 - 0.0059 15.9 1.1 0.0069 15.7 1.1 1.3 1 0 0 1 1 1 1 Mononegavirales mRNA-capping region V zf-CCCH_4 PF18044.1 EGR28473.1 - 5.8e-41 137.6 60.9 1.3e-08 34.4 3.0 6.1 6 0 0 6 6 6 6 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGR28473.1 - 1.8e-39 132.7 71.7 2.6e-07 30.5 3.7 6.2 6 0 0 6 6 6 6 Zinc finger domain zf-CCCH PF00642.24 EGR28473.1 - 6.2e-35 118.4 60.0 1.9e-08 34.0 2.7 6.2 5 1 1 6 6 6 6 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EGR28473.1 - 2.6e-18 66.7 44.2 0.00059 20.5 0.5 6.1 1 1 5 6 6 6 6 Torus domain zf-CCCH_2 PF14608.6 EGR28473.1 - 7.5e-15 54.8 60.5 0.00014 22.2 3.3 6.2 6 0 0 6 6 6 6 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 EGR28473.1 - 0.03 14.5 46.9 0.57 10.4 12.3 5.1 2 1 2 5 5 5 0 Zinc-finger containing family DUF3277 PF11681.8 EGR28473.1 - 0.33 10.8 1.0 1.4 8.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3277) zf-CCHH PF10283.9 EGR28473.1 - 8.4 6.5 52.9 2.1 8.4 2.0 7.9 8 0 0 8 8 8 0 PBZ domain Cep57_MT_bd PF06657.13 EGR28474.1 - 0.0032 17.9 6.0 0.22 12.0 0.4 2.4 2 0 0 2 2 2 2 Centrosome microtubule-binding domain of Cep57 IL2 PF00715.17 EGR28474.1 - 0.013 15.4 8.3 0.016 15.1 8.3 1.1 1 0 0 1 1 1 0 Interleukin 2 Ran-binding PF05508.11 EGR28474.1 - 0.058 12.4 12.4 0.068 12.2 12.4 1.1 1 0 0 1 1 1 0 RanGTP-binding protein UPF0242 PF06785.11 EGR28474.1 - 0.19 11.8 22.0 0.71 10.0 21.9 1.8 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus IMD PF08397.11 EGR28474.1 - 0.47 9.8 12.8 2.2 7.6 2.2 2.1 1 1 1 2 2 2 0 IRSp53/MIM homology domain Syntaxin-6_N PF09177.11 EGR28474.1 - 0.6 10.7 11.7 0.24 12.0 4.6 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal FlxA PF14282.6 EGR28474.1 - 0.71 9.9 23.3 97 3.0 22.4 2.4 1 1 0 1 1 1 0 FlxA-like protein Med21 PF11221.8 EGR28474.1 - 0.81 9.9 14.6 0.57 10.4 4.7 2.3 2 0 0 2 2 2 0 Subunit 21 of Mediator complex V_ATPase_I PF01496.19 EGR28474.1 - 2.9 5.7 14.8 3.5 5.4 14.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4140 PF13600.6 EGR28474.1 - 3.5 8.1 8.4 5.8 7.4 1.4 2.2 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) APG6_N PF17675.1 EGR28474.1 - 3.8 8.0 18.0 0.79 10.3 8.1 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region Uso1_p115_C PF04871.13 EGR28474.1 - 3.9 7.8 14.7 13 6.2 4.9 2.1 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region JIP_LZII PF16471.5 EGR28474.1 - 4.4 7.6 17.3 0.93 9.7 6.9 2.2 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II DivIC PF04977.15 EGR28474.1 - 4.7 7.1 17.2 2.6 7.9 5.2 2.4 2 0 0 2 2 2 0 Septum formation initiator Tweety PF04906.13 EGR28474.1 - 5.2 5.6 10.2 0.68 8.5 5.3 1.7 1 1 1 2 2 2 0 Tweety DUF1664 PF07889.12 EGR28474.1 - 6 6.9 13.6 10 6.2 9.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Spc24 PF08286.11 EGR28474.1 - 7.2 6.9 17.4 2.2 8.6 7.9 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Myb_DNA-binding PF00249.31 EGR28475.1 - 2.2e-10 40.6 2.0 3.5e-10 39.9 2.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGR28475.1 - 1.1e-09 38.4 2.9 1.8e-09 37.7 2.9 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain p25-alpha PF05517.12 EGR28478.1 - 7.4e-08 32.7 28.7 1.9e-07 31.4 0.2 4.8 3 2 1 5 5 5 2 p25-alpha DHC PF09626.10 EGR28479.1 - 0.14 13.1 1.2 0.18 12.7 0.4 1.6 2 0 0 2 2 2 0 Dihaem cytochrome c RRM_1 PF00076.22 EGR28480.1 - 6.8e-10 38.6 0.0 2e-09 37.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PWI PF01480.17 EGR28480.1 - 4.4e-09 36.5 0.7 4.4e-09 36.5 0.7 3.2 3 0 0 3 3 3 1 PWI domain Rtt106_N PF18215.1 EGR28480.1 - 0.0035 17.1 0.1 0.019 14.7 0.0 2.2 2 0 0 2 2 2 1 Histone chaperone Rtt106 N-terminal domain HPPK PF01288.20 EGR28480.1 - 2.3 8.8 6.6 14 6.3 0.1 3.7 3 1 1 4 4 4 0 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) BRCT_2 PF16589.5 EGR28481.1 - 0.021 15.2 7.4 0.58 10.6 7.4 2.7 1 1 0 1 1 1 0 BRCT domain, a BRCA1 C-terminus domain TerB_N PF13208.6 EGR28481.1 - 0.035 13.8 0.1 0.069 12.9 0.1 1.4 1 0 0 1 1 1 0 TerB N-terminal domain BRCT PF00533.26 EGR28481.1 - 7.9 6.9 9.5 28 5.2 5.3 3.0 1 1 1 2 2 2 0 BRCA1 C Terminus (BRCT) domain Ank_5 PF13857.6 EGR28482.1 - 8.9e-13 48.2 0.0 7.4e-10 38.9 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGR28482.1 - 1.6e-11 44.7 0.0 2.3e-10 40.9 0.0 2.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGR28482.1 - 5.7e-10 39.2 0.0 4.3e-06 26.9 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 EGR28482.1 - 6.2e-09 36.2 0.0 0.00016 22.2 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR28482.1 - 2.7e-07 30.4 0.0 0.00066 19.9 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat Ax_dynein_light PF10211.9 EGR28483.1 - 5.7e-79 264.4 23.2 7.3e-79 264.1 23.2 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain ERM PF00769.19 EGR28483.1 - 0.013 15.4 19.3 0.013 15.4 19.3 1.8 2 0 0 2 2 2 0 Ezrin/radixin/moesin family PolyA_pol_RNAbd PF12627.7 EGR28483.1 - 0.084 12.6 0.1 0.45 10.3 0.0 2.2 2 0 0 2 2 2 0 Probable RNA and SrmB- binding site of polymerase A GPW_gp25 PF04965.14 EGR28483.1 - 0.14 11.9 2.7 0.33 10.7 2.7 1.6 1 0 0 1 1 1 0 Gene 25-like lysozyme Tropomyosin_1 PF12718.7 EGR28483.1 - 0.2 11.8 24.7 0.038 14.1 20.8 1.7 2 0 0 2 2 2 0 Tropomyosin like UPF0061 PF02696.14 EGR28483.1 - 0.31 9.8 5.5 0.37 9.5 5.5 1.2 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family Syntaxin-6_N PF09177.11 EGR28483.1 - 1.1 9.8 15.7 0.19 12.3 11.6 1.8 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF1664 PF07889.12 EGR28483.1 - 2.7 8.0 9.5 1.3 9.0 7.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF16 PF01519.16 EGR28483.1 - 3.3 8.2 18.4 0.22 12.0 12.7 2.0 2 1 0 2 2 2 0 Protein of unknown function DUF16 Presenilin PF01080.17 EGR28483.1 - 4 6.1 9.4 6.6 5.4 9.4 1.3 1 0 0 1 1 1 0 Presenilin CENP-O PF09496.10 EGR28483.1 - 6.1 6.8 11.1 3.2 7.7 7.6 1.9 1 1 0 2 2 2 0 Cenp-O kinetochore centromere component Ax_dynein_light PF10211.9 EGR28484.1 - 6.7e-46 156.6 3.3 7.2e-46 156.5 3.3 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain RPEL PF02755.15 EGR28484.1 - 0.11 12.2 0.3 0.11 12.2 0.3 2.7 4 0 0 4 4 4 0 RPEL repeat Choline_transpo PF04515.12 EGR28485.1 - 9.4e-10 38.2 23.3 9.4e-10 38.2 23.3 2.9 1 1 2 3 3 3 1 Plasma-membrane choline transporter E1-E2_ATPase PF00122.20 EGR28485.1 - 0.14 11.6 0.0 0.14 11.6 0.0 4.0 3 1 1 4 4 4 0 E1-E2 ATPase DHHC PF01529.20 EGR28486.1 - 6.4e-32 110.5 23.6 6.4e-32 110.5 23.6 3.4 3 1 0 3 3 3 1 DHHC palmitoyltransferase Borrelia_REV PF03978.13 EGR28486.1 - 0.17 11.9 6.5 0.26 11.2 6.5 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi REV protein DPM3 PF08285.11 EGR28486.1 - 2.3 8.5 8.6 0.1 12.8 1.0 2.5 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) NDK PF00334.19 EGR28487.1 - 0.00037 20.5 0.0 0.00082 19.4 0.0 1.5 1 0 0 1 1 1 1 Nucleoside diphosphate kinase FAM221 PF14753.6 EGR28488.1 - 2.8e-59 200.0 17.3 5e-59 199.2 17.3 1.3 1 0 0 1 1 1 1 Protein FAM221A/B Trigger_C PF05698.14 EGR28488.1 - 0.33 11.0 5.0 6.7 6.7 1.1 2.2 2 0 0 2 2 2 0 Bacterial trigger factor protein (TF) C-terminus Transket_pyr PF02779.24 EGR28489.1 - 5.3e-60 202.1 0.0 9.4e-60 201.3 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EGR28489.1 - 1.9e-50 171.5 0.2 4.1e-50 170.4 0.2 1.5 2 0 0 2 2 2 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EGR28489.1 - 4e-46 156.5 0.4 9e-46 155.3 0.4 1.6 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EGR28489.1 - 9.9e-13 47.5 0.1 2.3e-12 46.3 0.1 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus PLU-1 PF08429.11 EGR28489.1 - 0.027 13.6 2.1 0.049 12.8 2.1 1.3 1 0 0 1 1 1 0 PLU-1-like protein DUF1087 PF06465.13 EGR28489.1 - 0.054 13.5 0.6 0.15 12.1 0.6 1.7 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1087) Adap_comp_sub PF00928.21 EGR28490.1 - 7.6e-84 281.2 1.0 9.7e-84 280.8 1.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGR28490.1 - 7.4e-05 22.7 6.5 0.00017 21.5 6.5 1.7 1 1 0 1 1 1 1 Clathrin adaptor complex small chain Longin PF13774.6 EGR28490.1 - 0.0013 18.7 0.4 0.004 17.2 0.4 1.9 1 0 0 1 1 1 1 Regulated-SNARE-like domain cNMP_binding PF00027.29 EGR28491.1 - 1.2e-14 54.1 0.1 2.8e-09 36.9 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain UPF0147 PF03685.13 EGR28491.1 - 0.064 13.3 1.8 0.19 11.8 1.8 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) DUF2397 PF09660.10 EGR28491.1 - 0.08 11.8 0.4 0.12 11.2 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2397) Prp18 PF02840.15 EGR28491.1 - 1.1 9.4 10.5 0.61 10.1 5.1 2.4 2 0 0 2 2 2 0 Prp18 domain PilJ PF13675.6 EGR28492.1 - 0.29 11.2 3.3 0.77 9.8 0.1 2.3 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Peptidase_M1 PF01433.20 EGR28494.1 - 1e-55 188.7 6.6 1e-55 188.7 6.6 2.3 2 1 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 EGR28494.1 - 2.3e-20 73.4 4.9 5.2e-20 72.2 4.9 1.7 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EGR28494.1 - 3.4e-18 66.5 0.7 1.6e-17 64.3 0.1 2.4 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Peptidase_MA_2 PF13485.6 EGR28494.1 - 0.015 15.0 1.0 0.038 13.7 1.0 1.6 1 0 0 1 1 1 0 Peptidase MA superfamily p25-alpha PF05517.12 EGR28495.1 - 0.081 13.1 1.2 0.13 12.4 1.2 1.3 1 0 0 1 1 1 0 p25-alpha adh_short PF00106.25 EGR28496.1 - 4.7e-44 150.2 2.2 1.2e-43 148.8 2.2 1.7 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGR28496.1 - 4e-35 121.5 0.6 6.3e-35 120.8 0.6 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 EGR28496.1 - 4.1e-22 78.6 0.2 9.3e-22 77.4 0.2 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family KR PF08659.10 EGR28496.1 - 3.4e-17 62.9 0.9 6.4e-17 62.0 0.9 1.3 1 0 0 1 1 1 1 KR domain Alkyl_sulf_C PF14864.6 EGR28496.1 - 1.1e-05 25.7 0.0 2e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal DIL PF01843.19 EGR28496.1 - 0.0091 16.3 0.1 0.016 15.5 0.1 1.3 1 0 0 1 1 1 1 DIL domain Dehyd-heme_bind PF09098.10 EGR28496.1 - 0.15 11.6 0.3 12 5.5 0.0 2.8 2 1 1 3 3 3 0 Quinohemoprotein amine dehydrogenase A, alpha subunit, haem binding PhoLip_ATPase_C PF16212.5 EGR28497.1 - 3.5e-45 154.7 8.7 3.5e-45 154.7 8.7 2.3 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGR28497.1 - 1.5e-23 82.2 3.4 1.5e-23 82.2 3.4 2.6 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGR28497.1 - 2.5e-13 50.8 0.1 9.1e-06 26.1 0.0 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGR28497.1 - 6e-10 39.1 0.0 4.1e-09 36.4 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGR28497.1 - 7.3e-09 35.4 0.0 2.5e-08 33.6 0.0 2.0 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGR28497.1 - 0.0001 22.1 0.9 0.00039 20.3 0.1 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase RRM_1 PF00076.22 EGR28498.1 - 7e-30 102.7 3.0 9.8e-16 57.3 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UQ_con PF00179.26 EGR28498.1 - 3.6e-19 68.8 1.3 1e-18 67.3 1.3 1.8 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Nup35_RRM_2 PF14605.6 EGR28498.1 - 1.3e-05 25.0 0.0 0.16 12.0 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif UEV PF05743.13 EGR28498.1 - 1.9e-05 24.5 0.0 4.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 UEV domain DUF1866 PF08952.11 EGR28498.1 - 0.072 12.9 0.0 1.9 8.3 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1866) tRNA-synt_2 PF00152.20 EGR28499.1 - 5.1e-77 259.0 0.1 5.1e-77 259.0 0.1 1.8 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGR28499.1 - 1.3e-12 47.5 0.0 3e-12 46.3 0.0 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGR28499.1 - 1.9e-06 27.6 0.1 0.0027 17.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) DUF4778 PF16008.5 EGR28499.1 - 0.021 14.9 3.1 0.034 14.2 3.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) Tim54 PF11711.8 EGR28499.1 - 0.77 8.5 18.3 1.3 7.7 18.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 LNS2 PF08235.13 EGR28500.1 - 8.6e-90 300.1 1.3 8.6e-90 300.1 1.3 2.1 2 0 0 2 2 2 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EGR28500.1 - 1.8e-29 101.7 0.4 7.1e-29 99.8 0.4 2.1 1 0 0 1 1 1 1 lipin, N-terminal conserved region LRR_9 PF14580.6 EGR28501.1 - 1.1e-06 28.3 1.1 1.1e-06 28.3 1.1 2.7 1 1 1 2 2 2 1 Leucine-rich repeat LRR_4 PF12799.7 EGR28501.1 - 0.0013 19.1 33.3 0.11 12.9 6.0 4.5 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGR28501.1 - 0.44 10.3 25.1 0.93 9.3 8.7 3.8 2 1 2 4 4 4 0 Leucine rich repeat DAPDH_C PF16654.5 EGR28501.1 - 2.4 8.0 4.4 1.6 8.6 0.1 2.5 3 0 0 3 3 3 0 Diaminopimelic acid dehydrogenase C-terminal domain Herpes_ICP4_N PF03584.15 EGR28502.1 - 0.0012 18.7 2.7 0.0053 16.6 0.2 2.7 2 1 0 2 2 2 1 Herpesvirus ICP4-like protein N-terminal region TPR_MLP1_2 PF07926.12 EGR28502.1 - 0.0055 16.8 6.3 0.0055 16.8 6.3 7.1 2 1 4 6 6 6 1 TPR/MLP1/MLP2-like protein GP57 PF17594.2 EGR28502.1 - 0.81 9.5 8.9 0.57 10.0 0.8 2.9 2 0 0 2 2 2 0 Phage Tail fiber assembly helper gene product 57 Ion_trans PF00520.31 EGR28504.1 - 1.7e-23 83.1 23.8 2.4e-23 82.6 23.8 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGR28504.1 - 3.2e-10 39.8 2.1 3.2e-10 39.8 2.1 2.8 3 0 0 3 3 3 1 Ion channel Lig_chan PF00060.26 EGR28504.1 - 0.21 11.4 3.5 0.096 12.5 0.4 2.0 2 0 0 2 2 2 0 Ligand-gated ion channel Sel1 PF08238.12 EGR28505.1 - 4.8e-20 71.5 5.7 1.3e-06 28.9 0.5 4.7 5 0 0 5 5 5 4 Sel1 repeat TPR_6 PF13174.6 EGR28505.1 - 0.059 14.0 2.2 55 4.7 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat PP2C PF00481.21 EGR28506.1 - 2.1e-49 168.5 0.0 2.6e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGR28506.1 - 0.00049 19.8 0.0 0.0019 17.9 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C Ras PF00071.22 EGR28507.1 - 5.2e-53 179.0 0.3 9.2e-53 178.2 0.3 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR28507.1 - 2.1e-31 108.6 0.8 4.7e-31 107.5 0.2 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR28507.1 - 2.7e-16 59.5 0.8 3.9e-16 59.0 0.8 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family TMEM107 PF14995.6 EGR28507.1 - 2.7e-10 40.8 4.6 4.9e-10 39.9 4.6 1.4 1 0 0 1 1 1 1 Transmembrane protein GTP_EFTU PF00009.27 EGR28507.1 - 7.1e-06 25.7 0.2 1.6e-05 24.5 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGR28507.1 - 1.4e-05 25.1 0.5 3.7e-05 23.8 0.2 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGR28507.1 - 0.00016 21.1 0.7 0.00038 19.9 0.3 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EGR28507.1 - 0.00071 19.1 0.1 0.0016 18.0 0.1 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 EGR28507.1 - 0.00086 19.3 0.7 0.1 12.5 0.0 2.5 1 1 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EGR28507.1 - 0.0013 19.0 0.2 0.0043 17.3 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGR28507.1 - 0.0029 18.0 0.0 0.0047 17.3 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 EGR28507.1 - 0.0049 16.3 0.0 0.012 15.0 0.0 1.6 1 0 0 1 1 1 1 Bacterial TniB protein cobW PF02492.19 EGR28507.1 - 0.0054 16.3 0.7 1.5 8.4 0.0 2.8 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain DUF3873 PF12989.7 EGR28507.1 - 0.024 15.0 0.0 0.05 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) AAA_19 PF13245.6 EGR28507.1 - 0.049 14.0 1.2 0.11 12.8 1.2 1.7 1 1 0 1 1 1 0 AAA domain SUR7 PF06687.12 EGR28507.1 - 0.074 12.7 0.8 0.15 11.7 0.8 1.5 1 0 0 1 1 1 0 SUR7/PalI family Pkinase PF00069.25 EGR28508.1 - 3.5e-41 141.3 0.9 4.9e-41 140.8 0.9 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28508.1 - 5.5e-30 104.5 0.0 8.1e-30 104.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ion_trans_2 PF07885.16 EGR28508.1 - 7.6e-14 51.4 10.1 2e-13 50.1 9.9 1.9 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGR28508.1 - 1.3e-11 44.2 6.9 2.1e-11 43.5 6.9 1.3 1 0 0 1 1 1 1 Ion transport protein Pkinase_fungal PF17667.1 EGR28508.1 - 2.1e-05 23.5 1.1 2.8e-05 23.1 0.0 1.7 3 0 0 3 3 3 1 Fungal protein kinase 14-3-3 PF00244.20 EGR28509.1 - 1.1e-96 322.6 6.1 1.3e-96 322.4 6.1 1.0 1 0 0 1 1 1 1 14-3-3 protein Pkinase PF00069.25 EGR28510.1 - 7.6e-47 159.9 3.3 4.7e-45 154.0 3.3 2.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28510.1 - 7.6e-22 77.8 2.4 1.5e-20 73.6 2.3 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase DnaJ PF00226.31 EGR28511.1 - 1.4e-21 76.3 2.2 1.4e-21 76.3 2.2 2.3 2 0 0 2 2 2 1 DnaJ domain Thioredoxin PF00085.20 EGR28511.1 - 2e-08 34.1 3.9 0.00013 21.9 0.4 2.8 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.6 EGR28511.1 - 0.0061 17.0 0.7 0.03 14.8 0.4 2.5 1 1 0 1 1 1 1 Thioredoxin-like domain HyaE PF07449.11 EGR28511.1 - 0.045 13.7 0.0 0.4 10.7 0.0 2.5 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Ribosomal_S7e PF01251.18 EGR28512.1 - 4.5e-61 205.8 9.7 5.1e-61 205.6 9.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e PTAC PF06130.12 EGR28512.1 - 0.0042 17.2 1.2 4.2 7.6 0.0 3.1 3 0 0 3 3 3 2 Phosphate propanoyltransferase Kelch_5 PF13854.6 EGR28513.1 - 3.9e-10 39.5 3.3 4e-05 23.5 0.1 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 EGR28513.1 - 5.1e-08 32.8 1.5 0.0055 16.7 0.1 2.2 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_1 PF01344.25 EGR28513.1 - 1.6e-07 30.8 1.3 0.00015 21.3 0.1 2.2 2 0 0 2 2 2 2 Kelch motif Kelch_6 PF13964.6 EGR28513.1 - 2.9e-06 27.3 2.8 0.012 15.9 0.2 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 EGR28513.1 - 2e-05 24.7 0.0 0.36 11.2 0.0 3.1 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_2 PF07646.15 EGR28513.1 - 6.4e-05 22.8 3.8 0.012 15.6 0.2 2.4 2 0 0 2 2 2 2 Kelch motif CDC45 PF02724.14 EGR28514.1 - 0.0025 16.2 8.7 0.0039 15.6 8.7 1.2 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.12 EGR28514.1 - 0.0046 15.2 12.1 0.013 13.7 12.1 1.8 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 EGR28514.1 - 0.01 15.3 13.3 0.016 14.7 13.3 1.2 1 0 0 1 1 1 0 SDA1 RPN2_C PF18004.1 EGR28514.1 - 6.5 6.6 8.2 14 5.6 8.2 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain cNMP_binding PF00027.29 EGR28516.1 - 5e-17 61.8 0.0 1e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGR28516.1 - 1.8e-07 31.0 0.3 3.5e-07 30.1 0.3 1.6 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGR28516.1 - 0.0021 17.4 0.6 0.0021 17.4 0.6 1.9 2 0 0 2 2 2 1 Ion transport protein DFF-C PF09033.10 EGR28516.1 - 0.16 11.8 2.2 0.35 10.8 2.2 1.5 1 0 0 1 1 1 0 DNA Fragmentation factor 45kDa, C terminal domain CsgF PF10614.9 EGR28516.1 - 0.54 10.5 6.0 0.081 13.2 1.2 2.0 2 0 0 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein RNA_pol_Rpb1_3 PF04983.18 EGR28516.1 - 5.1 7.0 11.4 0.13 12.2 1.6 2.6 2 1 0 2 2 2 0 RNA polymerase Rpb1, domain 3 SpoIIE PF07228.12 EGR28517.1 - 1e-09 38.6 0.0 1.5e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EGR28517.1 - 3.1e-06 27.0 0.9 0.0012 18.6 0.1 2.4 2 1 0 2 2 2 2 Protein phosphatase 2C NCE101 PF11654.8 EGR28517.1 - 0.39 10.5 0.1 0.39 10.5 0.1 1.7 2 0 0 2 2 2 0 Non-classical export protein 1 Spore_YhcN_YlaJ PF09580.10 EGR28517.1 - 1.4 8.9 5.6 4.5 7.3 0.9 2.3 2 0 0 2 2 2 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) PLL PF18587.1 EGR28517.1 - 4.4 7.5 8.4 0.41 10.8 1.1 2.6 3 1 0 3 3 3 0 PTX/LNS-Like (PLL) domain Kinesin PF00225.23 EGR28519.1 - 1.6e-98 329.7 5.9 1.6e-98 329.7 5.9 3.1 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EGR28519.1 - 2.3e-26 92.5 4.0 2.3e-26 92.5 4.0 3.7 4 1 0 4 4 4 1 Microtubule binding Turandot PF07240.11 EGR28519.1 - 0.055 13.4 0.3 0.23 11.5 0.3 2.1 1 0 0 1 1 1 0 Stress-inducible humoral factor Turandot LURAP PF14854.6 EGR28519.1 - 0.16 11.9 4.4 2 8.4 2.3 2.7 2 0 0 2 2 2 0 Leucine rich adaptor protein Sec7 PF01369.20 EGR28520.1 - 9.9e-54 181.8 2.6 9.9e-54 181.8 2.6 4.6 5 1 1 6 6 6 1 Sec7 domain Sec7_N PF12783.7 EGR28520.1 - 3.6e-37 127.7 6.8 3.6e-37 127.7 6.8 5.1 6 0 0 6 6 6 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EGR28520.1 - 2.2e-27 94.7 0.1 2.2e-27 94.7 0.1 8.0 9 0 0 9 9 9 2 Domain of unknown function (DUF1981) zf-HIT PF04438.16 EGR28520.1 - 0.032 14.1 2.0 0.071 13.0 2.0 1.6 1 0 0 1 1 1 0 HIT zinc finger Basic PF01586.16 EGR28520.1 - 3 9.1 7.0 0.49 11.6 0.5 3.1 3 0 0 3 3 3 0 Myogenic Basic domain Peptidase_C2 PF00648.21 EGR28521.1 - 1e-76 257.8 1.7 1.4e-76 257.3 1.7 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease GTP_EFTU PF00009.27 EGR28522.1 - 1.1e-51 175.1 0.4 1.1e-51 175.1 0.4 2.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGR28522.1 - 1.2e-16 60.5 0.0 3.7e-16 58.9 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus MMR_HSR1 PF01926.23 EGR28522.1 - 1.8e-06 28.0 0.7 1.8e-06 28.0 0.7 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 EGR28522.1 - 0.0044 17.2 0.1 0.02 15.1 0.1 2.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGR28522.1 - 0.0056 16.1 0.1 0.0056 16.1 0.1 3.1 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit Arf PF00025.21 EGR28522.1 - 0.034 13.6 0.3 0.034 13.6 0.3 2.5 3 0 0 3 3 3 0 ADP-ribosylation factor family Rota_NSP3 PF01665.16 EGR28522.1 - 1.8 7.6 13.8 20 4.2 7.3 3.5 3 0 0 3 3 3 0 Rotavirus non-structural protein NSP3 SOUL PF04832.12 EGR28524.1 - 1.8e-40 138.9 0.5 8.1e-40 136.7 0.5 1.8 1 1 0 1 1 1 1 SOUL heme-binding protein CmlA_N PF18456.1 EGR28524.1 - 0.0087 15.4 0.3 0.02 14.2 0.2 1.8 1 1 0 1 1 1 1 Diiron non-heme beta-hydroxylase N-terminal domain DUF5093 PF17011.5 EGR28524.1 - 0.016 15.5 1.9 0.016 15.5 1.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5093) 14-3-3 PF00244.20 EGR28525.1 - 1.2e-50 172.1 1.7 1.4e-50 171.9 1.7 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 EGR28525.1 - 0.0051 17.1 0.1 0.011 16.1 0.1 1.6 1 1 0 1 1 1 1 Tetratricopeptide repeat FlaF PF07309.11 EGR28525.1 - 0.026 14.6 0.4 0.041 13.9 0.1 1.5 2 0 0 2 2 2 0 Flagellar protein FlaF CH PF00307.31 EGR28526.1 - 7.4e-42 142.0 19.1 1.1e-14 54.5 0.7 4.3 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGR28526.1 - 0.0012 18.6 0.7 0.031 14.1 0.1 3.3 4 0 0 4 4 4 1 CAMSAP CH domain DUF4201 PF13870.6 EGR28528.1 - 1.8e-22 80.0 31.2 1.8e-22 80.0 31.2 4.5 4 1 0 4 4 4 1 Domain of unknown function (DUF4201) FHA PF00498.26 EGR28528.1 - 0.071 13.5 0.2 0.71 10.3 0.1 2.8 2 0 0 2 2 2 0 FHA domain Ydr279_N PF17745.1 EGR28528.1 - 0.1 12.9 5.7 0.14 12.4 0.3 3.6 4 0 0 4 4 4 0 Ydr279p protein triple barrel domain Radial_spoke_3 PF06098.11 EGR28529.1 - 1.1e-92 310.4 14.5 1.1e-92 310.4 14.5 2.3 1 1 1 2 2 2 1 Radial spoke protein 3 MotA_ExbB PF01618.16 EGR28529.1 - 0.2 11.4 0.1 0.2 11.4 0.1 2.3 2 1 0 2 2 2 0 MotA/TolQ/ExbB proton channel family VIT1 PF01988.19 EGR28530.1 - 0.0082 16.0 0.1 0.0082 16.0 0.1 3.6 5 0 0 5 5 5 1 VIT family DUF2284 PF10050.9 EGR28530.1 - 0.11 12.3 1.2 0.46 10.2 1.2 2.1 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) AsnC_trans_reg PF01037.21 EGR28530.1 - 0.15 12.0 0.1 0.44 10.6 0.1 1.8 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain Phage_holin_2_1 PF04971.12 EGR28530.1 - 6.2 6.9 7.9 0.33 11.0 0.5 2.8 3 0 0 3 3 3 0 Bacteriophage P21 holin S Methyltransf_28 PF02636.17 EGR28531.1 - 1.3e-55 188.8 0.2 1.8e-55 188.4 0.2 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Sec1 PF00995.23 EGR28532.1 - 4.4e-84 283.8 29.8 4.9e-84 283.6 29.8 1.0 1 0 0 1 1 1 1 Sec1 family Pex14_N PF04695.13 EGR28532.1 - 0.26 11.9 2.1 5.5 7.6 0.9 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ribosomal_L1 PF00687.21 EGR28533.1 - 2.1e-40 138.7 5.9 2.6e-40 138.4 5.9 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Pkinase PF00069.25 EGR28534.1 - 1.3e-62 211.6 0.0 1.4e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28534.1 - 6.6e-39 133.8 0.0 8e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28534.1 - 2.7e-08 33.5 0.0 3.2e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGR28534.1 - 1.5e-05 24.1 0.8 2.2e-05 23.6 0.8 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGR28534.1 - 0.0002 20.2 0.0 0.00026 19.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR28534.1 - 0.00079 18.8 0.0 0.001 18.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR28534.1 - 0.0037 17.2 0.0 0.044 13.7 0.3 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Cnd3 PF12719.7 EGR28535.1 - 1.7e-28 99.7 13.2 1.7e-28 99.7 13.2 3.6 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain VPS9 PF02204.18 EGR28536.1 - 2.5e-22 79.0 0.7 2.5e-22 79.0 0.7 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain DUF4370 PF14290.6 EGR28536.1 - 0.093 12.6 0.2 0.18 11.7 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4370) Pro_isomerase PF00160.21 EGR28537.1 - 6.6e-45 153.2 0.1 6.6e-45 153.2 0.1 2.9 2 1 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD THF_DHG_CYH_C PF02882.19 EGR28538.1 - 3.1e-40 137.1 1.6 3.5e-40 136.9 1.6 1.0 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain B9-C2 PF07162.11 EGR28539.1 - 1.7e-29 103.2 0.0 2.2e-29 102.8 0.0 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein MatE PF01554.18 EGR28540.1 - 4.7e-05 23.1 0.8 8e-05 22.3 0.0 1.6 2 0 0 2 2 2 1 MatE ASFV_L11L PF05293.11 EGR28540.1 - 1.1 9.6 6.5 2.4 8.6 6.5 1.5 1 0 0 1 1 1 0 African swine fever virus (ASFV) L11L protein WGG PF10273.9 EGR28541.1 - 0.29 11.8 3.6 0.34 11.6 0.1 2.8 3 0 0 3 3 3 0 Pre-rRNA-processing protein TSR2 Pkinase PF00069.25 EGR28542.1 - 3.7e-61 206.8 5.6 4.1e-61 206.6 5.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28542.1 - 9.3e-39 133.3 0.7 1.2e-38 132.9 0.7 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28542.1 - 1.8e-10 40.6 1.9 7e-10 38.7 1.9 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR28542.1 - 1.6e-05 24.4 0.1 3.2e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGR28542.1 - 3.2e-05 23.6 1.0 0.0096 15.5 0.1 2.3 1 1 1 2 2 2 2 Choline/ethanolamine kinase APH PF01636.23 EGR28542.1 - 0.0046 16.9 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGR28542.1 - 0.0093 14.8 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EGR28542.1 - 0.014 15.0 0.3 0.028 14.1 0.2 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Ras PF00071.22 EGR28543.1 - 6.1e-57 191.7 0.1 7.4e-57 191.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR28543.1 - 3.3e-34 117.7 0.0 5.7e-34 116.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR28543.1 - 3.7e-14 52.5 0.0 4.4e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR28543.1 - 1e-07 32.0 0.0 1.7e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGR28543.1 - 1.3e-06 28.0 0.0 1.7e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGR28543.1 - 2.6e-05 23.8 0.0 0.00084 18.9 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGR28543.1 - 0.00057 19.8 0.1 0.0033 17.3 0.0 2.2 2 1 1 3 3 3 1 RsgA GTPase AAA_16 PF13191.6 EGR28543.1 - 0.00087 19.7 0.0 0.002 18.5 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 EGR28543.1 - 0.0039 16.5 0.0 0.0085 15.4 0.0 1.6 1 0 0 1 1 1 1 Septin AAA_5 PF07728.14 EGR28543.1 - 0.0069 16.4 0.2 0.014 15.4 0.0 1.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) G-alpha PF00503.20 EGR28543.1 - 0.0073 15.5 2.3 0.12 11.5 0.1 2.2 1 1 1 2 2 2 1 G-protein alpha subunit AAA_22 PF13401.6 EGR28543.1 - 0.01 16.1 0.0 0.022 15.0 0.0 1.6 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 EGR28543.1 - 0.01 15.4 0.0 0.051 13.2 0.0 1.9 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 EGR28543.1 - 0.01 15.5 0.1 0.015 15.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGR28543.1 - 0.015 15.0 0.0 0.18 11.5 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EGR28543.1 - 0.03 13.8 0.0 0.061 12.8 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 EGR28543.1 - 0.033 14.0 0.4 4.2 7.1 0.1 2.6 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 EGR28543.1 - 0.039 13.5 0.0 0.065 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase_2 PF01637.18 EGR28543.1 - 0.041 13.8 0.2 0.09 12.7 0.0 1.7 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea TniB PF05621.11 EGR28543.1 - 0.046 13.1 0.0 0.064 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DAP3 PF10236.9 EGR28543.1 - 0.047 12.9 0.0 0.079 12.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 EGR28543.1 - 0.055 13.4 0.1 0.25 11.3 0.0 1.9 2 0 0 2 2 2 0 NACHT domain NB-ARC PF00931.22 EGR28543.1 - 0.067 12.4 0.5 0.13 11.5 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_9 PF12781.7 EGR28544.1 - 9.7e-70 234.1 8.4 9.7e-70 234.1 8.4 4.8 4 0 0 4 4 4 1 ATP-binding dynein motor region AAA_8 PF12780.7 EGR28544.1 - 2.4e-44 151.6 2.4 2.4e-44 151.6 2.4 3.2 4 1 0 4 4 4 1 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 EGR28544.1 - 1.6e-38 132.1 1.7 2.5e-38 131.5 0.1 2.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_C PF18199.1 EGR28544.1 - 5.4e-34 117.8 0.4 5.4e-34 117.8 0.4 3.3 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain Dynein_heavy PF03028.15 EGR28544.1 - 4.2e-33 114.0 11.7 1.1e-32 112.6 0.1 5.0 5 1 0 5 5 5 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EGR28544.1 - 1.9e-24 86.4 16.9 3.4e-24 85.5 16.9 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Exonuc_VII_L PF02601.15 EGR28544.1 - 0.0021 17.7 8.9 0.0021 17.7 8.9 4.0 4 0 0 4 4 4 1 Exonuclease VII, large subunit AAA_5 PF07728.14 EGR28544.1 - 0.069 13.1 0.0 0.38 10.8 0.0 2.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGR28544.1 - 1.1 9.6 10.1 15 5.9 0.5 4.7 4 1 1 5 5 5 0 AAA ATPase domain PEX11 PF05648.14 EGR28544.1 - 4.2 6.8 9.9 0.22 11.0 1.0 3.0 3 0 0 3 3 3 0 Peroxisomal biogenesis factor 11 (PEX11) Ank_2 PF12796.7 EGR28545.1 - 5.5e-31 107.0 9.4 2.4e-15 56.9 0.1 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGR28545.1 - 6.1e-27 93.6 11.0 9.9e-08 32.4 0.0 5.7 1 1 5 6 6 6 6 Ankyrin repeats (many copies) DHHC PF01529.20 EGR28545.1 - 2.5e-23 82.7 32.3 2.5e-23 82.7 32.3 3.2 2 2 0 2 2 2 1 DHHC palmitoyltransferase Ank_5 PF13857.6 EGR28545.1 - 3.8e-21 74.9 1.0 2.7e-06 27.5 0.0 4.6 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR28545.1 - 4.8e-21 72.6 1.0 0.0029 17.9 0.0 6.0 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 EGR28545.1 - 9.4e-19 67.0 0.8 0.00057 20.2 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ribosomal_L40e PF01020.17 EGR28545.1 - 0.24 11.3 6.3 0.74 9.7 6.3 1.8 1 0 0 1 1 1 0 Ribosomal L40e family Ribosomal_L6e PF01159.19 EGR28546.1 - 1.1e-10 42.0 2.0 1.1e-10 42.0 2.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L6e HEAT PF02985.22 EGR28547.1 - 1.1e-13 50.1 0.0 0.11 12.9 0.0 9.1 10 0 0 10 10 10 2 HEAT repeat HEAT_2 PF13646.6 EGR28547.1 - 5.3e-06 26.7 0.0 1.4 9.4 0.0 5.1 3 2 3 6 6 6 2 HEAT repeats TAF6_C PF07571.13 EGR28547.1 - 0.0068 16.7 0.3 1.9 8.9 0.0 3.7 3 1 0 4 4 4 1 TAF6 C-terminal HEAT repeat domain TP53IP5 PF15331.6 EGR28547.1 - 2.7 8.1 26.6 6.1 6.9 26.6 1.6 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 SHIPPO-rpt PF07004.12 EGR28548.1 - 0.016 16.1 19.9 1.8 9.6 0.2 5.0 4 1 0 4 4 4 0 Sperm-tail PG-rich repeat ABC_transp_aux PF09822.9 EGR28549.1 - 9.2e-08 31.9 0.0 1.6e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DDOST_48kD PF03345.14 EGR28549.1 - 0.0027 16.6 0.1 1.3 7.8 0.0 2.3 2 0 0 2 2 2 2 Oligosaccharyltransferase 48 kDa subunit beta IL23 PF16649.5 EGR28549.1 - 0.098 12.7 1.2 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 Interleukin 23 subunit alpha ThuA PF06283.11 EGR28549.1 - 0.12 12.6 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Trehalose utilisation Sec23_trunk PF04811.15 EGR28550.1 - 8.1e-33 114.0 1.7 1.7e-32 113.0 1.7 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EGR28550.1 - 2.4e-10 41.0 1.2 1.2e-09 38.8 0.3 2.6 2 1 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain IPPT PF01715.17 EGR28550.1 - 0.089 12.6 0.2 0.15 11.8 0.2 1.3 1 0 0 1 1 1 0 IPP transferase Pkinase PF00069.25 EGR28551.1 - 1.9e-43 148.7 12.1 1.9e-43 148.7 12.1 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28551.1 - 2e-26 92.8 3.4 4.2e-26 91.8 3.4 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR28551.1 - 0.011 15.1 0.3 0.025 13.9 0.3 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR28551.1 - 0.012 14.4 2.2 0.015 14.1 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase HTH_Tnp_Tc5 PF03221.16 EGR28551.1 - 0.072 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Tc5 transposase DNA-binding domain Bac_globin PF01152.21 EGR28554.1 - 5.5e-28 97.5 2.9 3.9e-10 39.9 0.1 3.0 3 0 0 3 3 3 3 Bacterial-like globin AhpC-TSA PF00578.21 EGR28555.1 - 5.4e-07 29.6 0.4 1.8e-06 27.9 0.0 2.0 2 1 0 2 2 2 1 AhpC/TSA family Phage_integrase PF00589.22 EGR28556.1 - 0.17 11.7 6.2 17 5.1 6.2 2.1 1 1 0 1 1 1 0 Phage integrase family LIP PF03583.14 EGR28556.1 - 2.7 7.3 4.9 4.3 6.6 0.6 2.0 1 1 1 2 2 2 0 Secretory lipase PRK PF00485.18 EGR28557.1 - 2.8e-43 148.0 0.0 5.5e-43 147.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EGR28557.1 - 4.9e-06 27.1 1.3 3.1e-05 24.5 0.0 2.9 3 1 0 4 4 4 1 AAA domain AAA_17 PF13207.6 EGR28557.1 - 0.0022 18.4 0.3 0.83 10.1 0.0 3.5 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 EGR28557.1 - 0.0077 15.5 0.0 0.027 13.7 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin Pkinase_Tyr PF07714.17 EGR28558.1 - 4.7e-43 147.3 0.0 5.3e-43 147.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGR28558.1 - 3e-37 128.4 0.0 3.5e-37 128.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Prolamin_like PF05617.11 EGR28558.1 - 0.057 13.6 0.0 0.091 12.9 0.0 1.4 1 0 0 1 1 1 0 Prolamin-like Pkinase_fungal PF17667.1 EGR28558.1 - 0.097 11.4 0.0 0.16 10.7 0.0 1.4 2 0 0 2 2 2 0 Fungal protein kinase Pkinase_Tyr PF07714.17 EGR28559.1 - 1e-19 70.9 1.7 2.1e-15 56.7 0.0 3.8 3 0 0 3 3 3 3 Protein tyrosine kinase Pyrophosphatase PF00719.19 EGR28560.1 - 2.1e-26 92.7 2.0 5.6e-26 91.3 2.0 1.8 1 0 0 1 1 1 1 Inorganic pyrophosphatase WD40 PF00400.32 EGR28560.1 - 3.2e-06 27.8 0.1 0.0046 17.8 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR28560.1 - 0.015 15.6 0.0 0.086 13.2 0.0 2.3 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF3698 PF12479.8 EGR28560.1 - 1.1 9.9 12.4 2.5 8.7 0.1 4.7 4 1 0 4 4 4 0 Protein of unknown function (DUF3698) Response_reg PF00072.24 EGR28561.1 - 1.9e-09 37.7 0.0 2.1e-09 37.5 0.0 1.0 1 0 0 1 1 1 1 Response regulator receiver domain Orthopox_A43R PF06517.11 EGR28561.1 - 0.06 13.2 0.0 0.06 13.2 0.0 1.1 1 0 0 1 1 1 0 Orthopoxvirus A43R protein PI-PLC-X PF00388.19 EGR28562.1 - 7.6e-61 203.9 0.2 7.6e-61 203.9 0.2 2.4 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EGR28562.1 - 3.6e-27 95.0 4.7 3.7e-27 94.9 0.0 3.2 1 1 2 3 3 3 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EGR28562.1 - 3.1e-13 49.9 0.0 1.3e-12 47.9 0.0 2.0 2 0 0 2 2 2 1 C2 domain PARG_cat PF05028.14 EGR28564.1 - 6.3e-68 229.6 9.6 7.8e-68 229.2 9.6 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) MORN PF02493.20 EGR28566.1 - 5.7e-26 88.8 55.8 1.3e-06 28.0 0.6 10.4 11 0 0 11 11 11 8 MORN repeat Peptidase_M1 PF01433.20 EGR28567.1 - 6.4e-49 166.5 10.0 6.4e-49 166.5 10.0 2.5 2 1 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EGR28567.1 - 4.7e-14 53.0 3.6 6.3e-14 52.6 0.7 2.7 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain ERAP1_C PF11838.8 EGR28567.1 - 1.5e-12 47.7 8.0 2.8e-12 46.8 8.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Apis_Csd PF11671.8 EGR28568.1 - 2.6 8.1 7.2 5.8 6.9 7.2 1.7 1 1 0 1 1 1 0 Complementary sex determiner protein Endonuclease_5 PF04493.14 EGR28570.1 - 2.2e-52 177.6 0.0 3e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V UvrC_HhH_N PF08459.11 EGR28570.1 - 0.0075 16.2 0.0 0.023 14.6 0.0 1.9 2 0 0 2 2 2 1 UvrC Helix-hairpin-helix N-terminal EMC3_TMCO1 PF01956.16 EGR28570.1 - 0.11 12.2 0.7 1.2 8.8 0.0 2.2 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Asp_protease PF09668.10 EGR28571.1 - 1.6e-51 173.3 0.4 2.6e-51 172.6 0.4 1.4 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 EGR28571.1 - 1.6e-20 73.5 1.0 4.2e-20 72.1 0.0 2.1 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGR28571.1 - 3.2e-08 34.1 0.0 8e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Aspartyl protease RVP PF00077.20 EGR28571.1 - 5.8e-06 26.5 4.7 1.4e-05 25.3 0.0 2.6 2 0 0 2 2 2 1 Retroviral aspartyl protease UBA PF00627.31 EGR28571.1 - 1.2e-05 25.0 0.0 1.2e-05 25.0 0.0 2.2 3 0 0 3 3 3 1 UBA/TS-N domain RVP_2 PF08284.11 EGR28571.1 - 9.6e-05 22.2 0.1 0.00019 21.2 0.1 1.5 1 0 0 1 1 1 1 Retroviral aspartyl protease UBA_4 PF14555.6 EGR28571.1 - 0.0045 16.8 0.1 0.011 15.5 0.1 1.7 1 0 0 1 1 1 1 UBA-like domain TFIIA PF03153.13 EGR28571.1 - 0.58 10.1 27.7 1.1 9.2 21.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 EGR28571.1 - 2 9.0 19.8 0.24 12.0 12.6 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Hydin_ADK PF17213.3 EGR28571.1 - 2.2 8.5 11.0 0.2 11.9 5.6 1.8 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain N6_N4_Mtase PF01555.18 EGR28571.1 - 2.9 7.5 8.4 0.21 11.3 2.9 1.7 2 0 0 2 2 2 0 DNA methylase Exonuc_VII_L PF02601.15 EGR28571.1 - 3.5 7.1 15.8 3.5 7.1 10.9 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit Tsg PF04668.12 EGR28571.1 - 3.7 8.2 13.5 0.26 12.0 0.7 2.6 2 0 0 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region FAM60A PF15396.6 EGR28571.1 - 7.4 6.5 10.0 4.7 7.2 5.6 2.0 2 0 0 2 2 2 0 Protein Family FAM60A Snf7 PF03357.21 EGR28572.1 - 1e-18 67.5 36.1 1e-18 67.5 36.1 2.9 2 1 1 3 3 3 1 Snf7 Me-amine-dh_L PF02975.14 EGR28572.1 - 0.18 12.3 0.2 0.18 12.3 0.2 2.6 3 0 0 3 3 3 0 Methylamine dehydrogenase, L chain HetR_C PF18460.1 EGR28572.1 - 0.98 9.4 7.0 3.2 7.7 0.1 2.6 2 1 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain Lsr2 PF11774.8 EGR28572.1 - 1.5 9.0 8.5 0.27 11.4 3.3 2.4 2 1 0 3 3 3 0 Lsr2 COG5 PF10392.9 EGR28572.1 - 5.1 7.3 20.1 0.11 12.7 1.0 3.2 2 1 0 3 3 3 0 Golgi transport complex subunit 5 Glyco_hydro_100 PF12899.7 EGR28573.1 - 0.0056 15.4 0.9 0.011 14.4 0.9 1.4 1 0 0 1 1 1 1 Alkaline and neutral invertase 5_nucleotid_C PF02872.18 EGR28575.1 - 2.5e-39 135.0 0.0 3.7e-39 134.5 0.0 1.3 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EGR28575.1 - 2.1e-11 44.7 0.2 5e-11 43.5 0.1 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Utp14 PF04615.13 EGR28577.1 - 3e-38 131.9 5.5 3.7e-38 131.7 5.5 1.0 1 0 0 1 1 1 1 Utp14 protein EF-hand_6 PF13405.6 EGR28578.1 - 3.6e-20 70.1 17.3 0.0001 22.0 0.1 6.8 6 0 0 6 6 6 5 EF-hand domain EF-hand_1 PF00036.32 EGR28578.1 - 4.6e-18 63.3 20.6 0.00023 20.5 0.1 6.6 6 0 0 6 6 6 5 EF hand EF-hand_7 PF13499.6 EGR28578.1 - 4.4e-16 59.1 27.9 1.4e-08 35.0 1.6 5.4 6 0 0 6 6 6 3 EF-hand domain pair EF-hand_8 PF13833.6 EGR28578.1 - 1.9e-14 53.2 8.2 7.1e-09 35.4 0.8 5.4 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 EGR28578.1 - 1.7e-10 39.9 14.5 0.00043 19.7 0.1 4.8 5 0 0 5 5 5 3 EF hand DUF5110 PF17137.4 EGR28578.1 - 0.046 14.0 0.3 0.26 11.6 0.3 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5110) Rep_fac_C PF08542.11 EGR28578.1 - 0.29 11.6 0.0 0.29 11.6 0.0 4.3 3 1 1 4 4 4 0 Replication factor C C-terminal domain Guanylate_cyc PF00211.20 EGR28579.1 - 8e-13 48.4 0.0 1.8e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ion_trans PF00520.31 EGR28579.1 - 3.2e-05 23.3 6.9 3.2e-05 23.3 6.9 2.1 2 0 0 2 2 2 1 Ion transport protein LRR_6 PF13516.6 EGR28581.1 - 1.2e-06 28.1 3.2 0.0067 16.4 0.1 3.7 3 0 0 3 3 3 2 Leucine Rich repeat Flavi_NS1 PF00948.21 EGR28581.1 - 0.018 13.9 0.7 0.026 13.4 0.7 1.3 1 0 0 1 1 1 0 Flavivirus non-structural Protein NS1 Syntaxin-6_N PF09177.11 EGR28581.1 - 4.3 8.0 27.6 2.9 8.5 6.9 4.3 1 1 2 3 3 3 0 Syntaxin 6, N-terminal BK_channel_a PF03493.18 EGR28582.1 - 7.9e-35 119.0 0.9 1.2e-33 115.2 0.5 2.6 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 EGR28582.1 - 1.7e-10 40.7 0.9 3.7e-10 39.6 0.9 1.5 1 0 0 1 1 1 1 Ion channel TrkA_N PF02254.18 EGR28582.1 - 0.0022 18.3 0.4 1.2 9.4 0.2 2.5 2 0 0 2 2 2 2 TrkA-N domain Lig_chan PF00060.26 EGR28582.1 - 0.16 11.8 0.0 0.28 11.0 0.0 1.4 1 0 0 1 1 1 0 Ligand-gated ion channel Nop PF01798.18 EGR28583.1 - 2.1e-80 269.5 0.2 2.1e-80 269.5 0.2 2.4 3 0 0 3 3 3 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EGR28583.1 - 1.7e-14 53.9 0.7 1.7e-14 53.9 0.7 3.0 3 0 0 3 3 3 1 NOP5NT (NUC127) domain RGS12_us1 PF16613.5 EGR28583.1 - 1.1 9.5 0.0 1.1 9.5 0.0 2.5 2 0 0 2 2 2 0 Unstructured region of RGS12 Brix PF04427.18 EGR28584.1 - 7.7e-27 94.6 0.6 1.4e-26 93.8 0.6 1.4 1 0 0 1 1 1 1 Brix domain Membralin PF09746.9 EGR28584.1 - 0.92 8.5 4.1 11 4.9 3.8 2.0 2 0 0 2 2 2 0 Tumour-associated protein RCC1 PF00415.18 EGR28585.1 - 1e-73 243.7 17.9 9.6e-12 45.3 0.1 7.7 6 1 1 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR28585.1 - 2.4e-43 145.1 39.1 1.3e-09 37.6 1.9 8.3 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat EF-hand_6 PF13405.6 EGR28586.1 - 2.3e-12 45.8 1.6 8.5e-06 25.3 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGR28586.1 - 3.6e-12 44.9 2.7 2.4e-06 26.7 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGR28586.1 - 5.8e-10 38.2 1.4 0.00024 20.4 0.4 2.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGR28586.1 - 1.6e-09 38.0 0.4 2e-09 37.8 0.4 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGR28586.1 - 0.00014 21.6 1.2 0.062 13.1 0.5 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EGR28586.1 - 0.0039 17.5 0.0 1.7 9.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 EGR28586.1 - 0.0053 16.9 0.9 0.79 10.0 1.9 2.2 1 1 1 2 2 2 2 Dockerin type I domain Dpy-30 PF05186.13 EGR28587.1 - 4.3e-09 35.9 0.3 5.9e-09 35.5 0.3 1.2 1 0 0 1 1 1 1 Dpy-30 motif Cullin PF00888.22 EGR28588.1 - 1.2e-50 172.8 38.6 1.1e-47 163.0 21.9 2.9 1 1 1 3 3 3 2 Cullin family Cullin_Nedd8 PF10557.9 EGR28588.1 - 1.1e-21 76.6 9.2 1.5e-21 76.2 5.5 3.2 2 0 0 2 2 2 1 Cullin protein neddylation domain Mistic PF11458.8 EGR28588.1 - 0.0076 16.2 8.7 0.89 9.6 1.1 4.5 4 0 0 4 4 4 2 Membrane-integrating protein Mistic HD_4 PF13328.6 EGR28588.1 - 0.016 14.9 0.1 0.037 13.8 0.1 1.5 1 0 0 1 1 1 0 HD domain DUF4083 PF13314.6 EGR28588.1 - 0.077 12.9 0.5 0.077 12.9 0.5 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) DUF382 PF04037.13 EGR28588.1 - 0.54 10.4 7.3 0.23 11.6 0.5 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF382) Pkinase PF00069.25 EGR28589.1 - 0.012 15.0 0.0 0.034 13.5 0.0 1.7 2 0 0 2 2 2 0 Protein kinase domain DSPc PF00782.20 EGR28590.1 - 3.3e-15 56.1 0.4 3.3e-15 56.1 0.4 3.7 2 1 1 3 3 3 1 Dual specificity phosphatase, catalytic domain VCBS PF13517.6 EGR28592.1 - 1.5e-20 73.5 11.9 3.4e-07 30.8 0.3 4.3 4 0 0 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 EGR28592.1 - 0.0023 17.3 0.3 4.9 6.5 0.0 4.9 4 2 1 5 5 5 1 Insecticide toxin TcdB middle/N-terminal region Cys_rich_CPCC PF14206.6 EGR28592.1 - 0.017 14.9 0.2 0.055 13.3 0.2 1.8 1 0 0 1 1 1 0 Cysteine-rich CPCC EF-hand_5 PF13202.6 EGR28592.1 - 0.083 12.4 3.6 2.9 7.5 0.2 3.1 2 0 0 2 2 2 0 EF hand OSTbeta PF15048.6 EGR28592.1 - 0.16 12.1 0.2 0.37 10.9 0.2 1.6 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Vpu PF00558.19 EGR28592.1 - 0.16 11.8 2.4 0.4 10.5 0.1 2.5 2 0 0 2 2 2 0 Vpu protein Pentapeptide_4 PF13599.6 EGR28592.1 - 0.33 11.2 4.8 1.4 9.1 2.6 2.7 2 0 0 2 2 2 0 Pentapeptide repeats (9 copies) FG-GAP PF01839.23 EGR28592.1 - 2.5 8.3 19.4 10 6.4 0.1 6.0 7 0 0 7 7 7 0 FG-GAP repeat SLR1-BP PF07333.12 EGR28592.1 - 7.8 7.0 8.4 12 6.4 0.5 3.8 3 0 0 3 3 3 0 S locus-related glycoprotein 1 binding pollen coat protein (SLR1-BP) SF-assemblin PF06705.11 EGR28593.1 - 2.1e-10 40.4 32.7 1.1e-07 31.5 24.3 2.8 1 1 1 2 2 2 2 SF-assemblin/beta giardin Baculo_PEP_C PF04513.12 EGR28593.1 - 0.026 14.6 20.4 0.18 11.8 2.5 2.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus T4_tail_cap PF11091.8 EGR28593.1 - 0.036 13.0 3.0 0.043 12.8 2.1 1.6 1 1 0 1 1 1 0 Tail-tube assembly protein BMFP PF04380.13 EGR28593.1 - 0.16 12.4 11.8 0.52 10.8 0.2 3.8 3 1 2 5 5 5 0 Membrane fusogenic activity DUF3037 PF11236.8 EGR28593.1 - 0.56 10.6 9.8 3.8 8.0 1.4 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3037) DUF148 PF02520.17 EGR28593.1 - 1.9 8.6 29.6 0.53 10.4 8.6 3.2 1 1 3 4 4 4 0 Domain of unknown function DUF148 DUF1664 PF07889.12 EGR28593.1 - 8 6.5 18.5 10 6.2 4.5 3.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) DUF4208 PF13907.6 EGR28593.1 - 8.8 6.8 14.3 7.8 7.0 2.0 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF4208) Dpy-30 PF05186.13 EGR28594.1 - 0.0018 18.0 0.1 0.0041 16.8 0.1 1.7 1 0 0 1 1 1 1 Dpy-30 motif Pet100 PF09803.9 EGR28594.1 - 2.3 8.8 11.7 0.25 11.9 4.2 3.2 2 0 0 2 2 2 0 Pet100 DUF1295 PF06966.12 EGR28595.1 - 1.6e-22 80.2 6.5 3.2e-22 79.2 6.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) RSN1_7TM PF02714.15 EGR28597.1 - 2.5e-06 27.0 23.7 2.5e-06 27.0 23.7 4.2 4 2 1 5 5 5 1 Calcium-dependent channel, 7TM region, putative phosphate vATP-synt_E PF01991.18 EGR28598.1 - 3.4e-33 114.7 14.0 4.3e-33 114.4 14.0 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DASH_Dad1 PF08649.10 EGR28598.1 - 0.33 11.2 4.9 0.2 11.9 1.3 2.6 3 0 0 3 3 3 0 DASH complex subunit Dad1 UCH PF00443.29 EGR28599.1 - 1.6e-38 132.7 31.8 1.9e-37 129.1 31.8 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR28599.1 - 2.3e-21 76.7 38.9 2.4e-20 73.4 32.5 4.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-DBF PF07535.12 EGR28599.1 - 1.6 8.9 6.7 3.6 7.8 0.4 3.0 2 0 0 2 2 2 0 DBF zinc finger adh_short_C2 PF13561.6 EGR28600.1 - 3.5e-53 180.5 0.0 4.3e-53 180.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGR28600.1 - 4.2e-48 163.4 0.4 5e-48 163.2 0.4 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGR28600.1 - 1.2e-05 25.3 0.0 1.5e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF2620 PF10941.8 EGR28600.1 - 0.04 14.1 0.1 0.71 10.0 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function DUF2620 Kinesin PF00225.23 EGR28601.1 - 3.6e-108 361.4 5.0 3.6e-108 361.4 5.0 3.0 3 1 1 4 4 4 1 Kinesin motor domain PIP5K PF01504.18 EGR28601.1 - 3.8e-33 114.9 3.2 3.8e-33 114.9 3.2 3.3 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Microtub_bd PF16796.5 EGR28601.1 - 4.7e-25 88.3 0.4 4.7e-25 88.3 0.4 3.9 4 1 0 4 4 4 1 Microtubule binding MatP_C PF17414.2 EGR28601.1 - 0.033 14.4 1.5 0.31 11.3 1.5 2.8 1 0 0 1 1 1 0 MatP C-terminal ribbon-helix-helix domain DUF3410 PF11890.8 EGR28601.1 - 0.063 13.1 1.7 0.21 11.4 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3410) CoA_binding PF02629.19 EGR28602.1 - 7.3e-31 106.7 1.1 7.3e-31 106.7 1.1 2.3 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EGR28602.1 - 3e-23 82.3 0.1 5.3e-23 81.5 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EGR28602.1 - 3.2e-10 39.9 0.0 6.6e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EGR28602.1 - 3.9e-06 27.3 0.1 1.1e-05 25.9 0.1 1.8 1 0 0 1 1 1 1 CoA binding domain GFO_IDH_MocA PF01408.22 EGR28602.1 - 0.0019 19.0 0.2 0.0059 17.4 0.1 2.0 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Mpp10 PF04006.12 EGR28604.1 - 0.00073 18.1 38.6 0.0008 18.0 38.6 1.0 1 0 0 1 1 1 1 Mpp10 protein SDA1 PF05285.12 EGR28604.1 - 0.016 14.7 37.8 0.016 14.6 37.8 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EGR28604.1 - 0.44 8.7 41.1 0.47 8.6 41.1 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EGR28604.1 - 0.82 7.9 28.0 1.1 7.5 28.0 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF789 PF05623.12 EGR28604.1 - 1.4 8.5 5.1 1.5 8.4 5.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF789) BUD22 PF09073.10 EGR28604.1 - 1.5 8.1 32.5 1.6 8.0 32.5 1.1 1 0 0 1 1 1 0 BUD22 Presenilin PF01080.17 EGR28604.1 - 3.6 6.3 9.2 3.9 6.1 9.2 1.1 1 0 0 1 1 1 0 Presenilin RNA_polI_A34 PF08208.11 EGR28604.1 - 3.7 7.6 18.2 5.4 7.1 18.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 tRNA-synt_1c PF00749.21 EGR28605.1 - 1.7e-110 368.8 1.4 2.8e-110 368.1 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGR28605.1 - 2.9e-37 128.2 0.3 5.8e-37 127.2 0.3 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.15 EGR28605.1 - 2.8e-23 82.7 1.5 9.2e-11 42.0 0.0 2.5 1 1 1 2 2 2 2 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 Peptidase_M28 PF04389.17 EGR28606.1 - 5.1e-20 72.0 0.1 1.1e-19 70.9 0.1 1.6 1 1 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGR28606.1 - 3e-08 33.6 0.0 7.7e-08 32.3 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M20/M25/M40 PA PF02225.22 EGR28606.1 - 2.8e-06 27.3 0.0 5.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 PA domain Lip_A_acyltrans PF03279.13 EGR28606.1 - 0.097 11.8 0.0 0.43 9.7 0.0 1.9 2 0 0 2 2 2 0 Bacterial lipid A biosynthesis acyltransferase ChapFlgA_N PF17656.1 EGR28606.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 FlgA N-terminal domain Pkinase PF00069.25 EGR28607.1 - 0.0087 15.4 0.0 0.01 15.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain RNase_HII PF01351.18 EGR28608.1 - 7.9e-40 136.8 0.0 3.4e-23 82.5 0.0 2.1 1 1 1 2 2 2 2 Ribonuclease HII DUF3516 PF12029.8 EGR28608.1 - 0.059 12.5 0.4 0.073 12.1 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) DUF3806 PF12713.7 EGR28608.1 - 0.13 12.1 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3806) tRNA-synt_1b PF00579.25 EGR28609.1 - 8.2e-53 179.6 0.0 8.2e-53 179.6 0.0 1.7 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) AAA_23 PF13476.6 EGR28609.1 - 0.32 11.5 16.2 1.6 9.2 10.0 2.3 2 0 0 2 2 2 0 AAA domain Vps39_1 PF10366.9 EGR28609.1 - 0.68 10.2 8.7 1.8 8.9 8.7 1.7 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 1 FAD_SOX PF18371.1 EGR28609.1 - 3.3 8.1 11.3 0.66 10.4 6.1 2.3 2 0 0 2 2 2 0 Flavin adenine dinucleotide (FAD)-dependent sulfhydryl oxidase YL1 PF05764.13 EGR28610.1 - 0.00024 21.3 43.8 0.00024 21.3 43.8 2.2 3 0 0 3 3 3 1 YL1 nuclear protein DUF2756 PF10956.8 EGR28610.1 - 0.018 15.6 6.6 0.018 15.6 6.6 3.8 3 1 0 3 3 3 0 Protein of unknown function (DUF2756) Drc1-Sld2 PF11719.8 EGR28610.1 - 0.047 13.2 39.5 0.072 12.6 39.5 1.3 1 0 0 1 1 1 0 DNA replication and checkpoint protein Draxin PF15550.6 EGR28610.1 - 9.6 6.0 28.7 20 5.0 28.7 1.4 1 0 0 1 1 1 0 Draxin Na_H_Exchanger PF00999.21 EGR28611.1 - 9.4e-40 136.6 24.6 1.3e-39 136.1 24.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family NnrS PF05940.12 EGR28611.1 - 0.013 14.9 1.8 0.013 14.9 1.8 1.9 1 1 1 2 2 2 0 NnrS protein NiFe_hyd_3_EhaA PF17367.2 EGR28611.1 - 0.24 11.6 19.4 0.26 11.4 1.6 4.2 3 1 1 4 4 4 0 NiFe-hydrogenase-type-3 Eha complex subunit A DUF4576 PF15144.6 EGR28611.1 - 3.2 7.7 5.3 3.3 7.6 0.2 3.2 3 1 1 4 4 4 0 Domain of unknown function (DUF4576) DUF2606 PF10794.9 EGR28612.1 - 0.078 12.8 0.9 0.15 11.9 0.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2606) XPG_N PF00752.17 EGR28613.1 - 2e-20 73.2 0.1 7.3e-20 71.3 0.1 2.1 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EGR28613.1 - 3.5e-19 68.9 0.1 3.5e-19 68.9 0.1 3.8 4 1 0 4 4 4 1 XPG I-region XPG_I_2 PF12813.7 EGR28613.1 - 2.1e-05 24.2 0.1 2.1e-05 24.2 0.1 2.1 2 1 0 2 2 2 1 XPG domain containing 5_3_exonuc PF01367.20 EGR28613.1 - 0.004 17.7 9.3 0.012 16.2 0.0 4.0 3 1 0 3 3 3 1 5'-3' exonuclease, C-terminal SAM fold DUF3303 PF11746.8 EGR28613.1 - 0.017 15.4 0.0 0.043 14.1 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3303) zf-RING_10 PF16685.5 EGR28613.1 - 3.5 7.8 6.5 0.41 10.8 0.9 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 Helicase_C PF00271.31 EGR28616.1 - 8.9e-13 48.6 1.7 8.9e-13 48.6 1.7 2.3 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGR28616.1 - 0.00032 20.5 0.1 0.00057 19.7 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGR28616.1 - 0.045 13.8 3.7 0.1 12.6 3.7 1.7 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DNA_pol_phi PF04931.13 EGR28616.1 - 0.049 11.7 14.3 0.067 11.3 14.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi Myc_N PF01056.18 EGR28616.1 - 0.15 12.0 5.4 0.2 11.5 5.4 1.3 1 0 0 1 1 1 0 Myc amino-terminal region GIDA_assoc PF13932.6 EGR28616.1 - 0.2 11.8 4.4 0.2 11.8 3.1 1.6 2 0 0 2 2 2 0 GidA associated domain DUF4611 PF15387.6 EGR28616.1 - 2.3 8.5 10.4 0.076 13.2 2.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) NAD_binding_1 PF00175.21 EGR28617.1 - 1.7e-25 89.8 0.1 3.4e-25 88.8 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EGR28617.1 - 3.1e-08 33.9 0.7 1.3e-06 28.6 0.7 2.4 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_6 PF00970.24 EGR28617.1 - 4.6e-05 23.7 0.0 8.4e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain MFS_2 PF13347.6 EGR28618.1 - 2.1e-23 82.6 36.1 9.1e-22 77.2 36.1 3.0 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 EGR28618.1 - 1.5e-15 57.0 15.1 1.5e-15 57.0 15.1 1.3 1 1 0 1 1 1 1 Major Facilitator Superfamily GP41 PF00517.17 EGR28618.1 - 1.1 9.1 7.3 0.11 12.4 0.4 2.6 3 0 0 3 3 3 0 Retroviral envelope protein Pkinase PF00069.25 EGR28619.1 - 1.1e-64 218.4 2.0 3.8e-64 216.6 2.0 2.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28619.1 - 2.2e-46 158.2 0.3 3.9e-46 157.4 0.3 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR28619.1 - 0.0037 16.6 0.2 0.0094 15.3 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR28619.1 - 0.022 14.7 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family MFS_1 PF07690.16 EGR28620.1 - 1.6e-05 24.0 5.3 0.0025 16.8 2.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EGR28620.1 - 0.0028 16.6 3.3 0.009 14.9 0.7 1.9 1 1 1 2 2 2 1 MFS_1 like family DUF4368 PF14287.6 EGR28620.1 - 0.089 13.1 0.0 0.18 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) DUF3792 PF12670.7 EGR28620.1 - 1.9 8.7 12.2 0.13 12.5 5.8 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) Senescence PF06911.12 EGR28621.1 - 0.11 12.8 8.4 0.25 11.6 6.7 2.4 2 0 0 2 2 2 0 Senescence-associated protein Imm59 PF15597.6 EGR28621.1 - 1.7 9.2 6.8 20 5.7 0.0 4.3 3 0 0 3 3 3 0 Immunity protein 59 SCHIP-1 PF10148.9 EGR28622.1 - 0.059 13.0 0.1 0.059 13.0 0.1 1.1 1 0 0 1 1 1 0 Schwannomin-interacting protein 1 Beta_helix PF13229.6 EGR28623.1 - 5.4e-30 104.3 63.3 3.4e-11 43.3 19.6 3.4 1 1 2 3 3 3 3 Right handed beta helix region NosD PF05048.13 EGR28623.1 - 3.5e-26 92.0 55.4 2.1e-14 53.4 17.4 3.2 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 EGR28623.1 - 7.1e-06 25.5 51.4 0.0007 19.0 0.0 5.2 2 1 3 5 5 5 3 Protein of unknown function (DUF1565) Mito_carr PF00153.27 EGR28626.1 - 1.7e-43 146.4 7.8 9e-18 64.0 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Endosulfine PF04667.17 EGR28627.1 - 0.62 10.2 7.2 0.52 10.5 2.8 2.5 1 1 1 2 2 2 0 cAMP-regulated phosphoprotein/endosulfine conserved region Pkinase PF00069.25 EGR28628.1 - 1.3e-15 57.4 0.1 4.7e-07 29.4 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28628.1 - 1.1e-06 28.1 0.0 0.00045 19.6 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase ABC1 PF03109.16 EGR28628.1 - 0.0096 16.1 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 1 ABC1 family UvrD_C_2 PF13538.6 EGR28631.1 - 0.0013 18.5 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain AAA_7 PF12775.7 EGR28631.1 - 0.0021 17.6 0.2 0.0062 16.1 0.2 1.8 1 0 0 1 1 1 1 P-loop containing dynein motor region DEAD PF00270.29 EGR28631.1 - 0.037 13.8 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 DEAD/DEAH box helicase CobT PF06213.12 EGR28631.1 - 0.083 12.3 25.3 0.082 12.3 22.5 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT AAA_16 PF13191.6 EGR28631.1 - 0.25 11.7 1.8 2 8.8 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain DUF3402 PF11882.8 EGR28632.1 - 1.1e-09 38.0 4.2 1.1e-09 38.0 4.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3402) RabGAP-TBC PF00566.18 EGR28633.1 - 4.7e-05 23.1 17.1 4.7e-05 23.1 17.1 2.9 1 1 1 2 2 2 1 Rab-GTPase-TBC domain Ctr PF04145.15 EGR28633.1 - 6.6 7.3 8.1 10 6.7 5.8 2.2 1 1 1 2 2 2 0 Ctr copper transporter family His_Phos_2 PF00328.22 EGR28634.1 - 6.1e-05 22.5 0.1 0.0025 17.2 0.0 2.6 1 1 2 3 3 3 2 Histidine phosphatase superfamily (branch 2) Aldedh PF00171.22 EGR28636.1 - 1.6e-46 158.8 0.0 1.8e-46 158.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.25 EGR28637.1 - 2.3e-52 178.0 7.4 2.3e-52 178.0 7.4 3.2 2 2 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28637.1 - 2.2e-19 69.8 0.4 2.2e-19 69.8 0.4 2.1 2 1 1 3 3 3 1 Protein tyrosine kinase APH PF01636.23 EGR28637.1 - 0.0068 16.3 0.4 0.014 15.4 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family CGGC PF08821.11 EGR28637.1 - 0.011 16.0 0.7 0.055 13.7 0.1 2.5 2 0 0 2 2 2 0 CGGC domain PA_decarbox PF05870.11 EGR28637.1 - 0.28 10.8 4.5 0.35 10.5 1.2 2.7 2 1 1 3 3 3 0 Phenolic acid decarboxylase (PAD) BSMAP PF12280.8 EGR28637.1 - 9 6.5 10.7 3.8 7.7 0.1 2.2 2 0 0 2 2 2 0 Brain specific membrane anchored protein Pept_tRNA_hydro PF01195.19 EGR28638.1 - 4.2e-21 75.7 1.3 7e-21 74.9 1.3 1.4 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase tRNA_int_endo PF01974.17 EGR28638.1 - 0.00012 22.1 0.1 0.058 13.5 0.0 2.3 1 1 1 2 2 2 2 tRNA intron endonuclease, catalytic C-terminal domain Complex1_LYR PF05347.15 EGR28639.1 - 9.1e-08 32.0 0.0 1.9e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Complex 1 protein (LYR family) SCP2 PF02036.17 EGR28640.1 - 2.2e-24 85.9 0.2 2.7e-24 85.6 0.2 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EGR28640.1 - 0.004 17.4 0.1 0.0052 17.1 0.1 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal ApoA-II PF04711.13 EGR28640.1 - 0.14 12.3 0.3 0.32 11.2 0.2 1.7 2 0 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) AAA PF00004.29 EGR28641.1 - 6.6e-43 146.3 0.0 9.4e-43 145.8 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGR28641.1 - 1.6e-05 24.7 0.0 3.7e-05 23.5 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGR28641.1 - 2.6e-05 24.7 0.0 0.00044 20.7 0.0 2.1 1 1 1 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 EGR28641.1 - 4.3e-05 23.9 0.0 7.9e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 EGR28641.1 - 0.00018 21.5 0.0 0.00028 20.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGR28641.1 - 0.0002 21.4 0.0 0.00099 19.1 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGR28641.1 - 0.00036 20.7 0.0 0.00081 19.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EGR28641.1 - 0.0005 19.4 0.0 0.00073 18.8 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_25 PF13481.6 EGR28641.1 - 0.0018 17.9 0.0 0.68 9.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_lid_3 PF17862.1 EGR28641.1 - 0.0021 17.8 0.1 0.0044 16.8 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain TsaE PF02367.17 EGR28641.1 - 0.0022 18.0 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EGR28641.1 - 0.0033 17.0 0.0 0.0054 16.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region Rad17 PF03215.15 EGR28641.1 - 0.0039 17.1 0.0 0.0072 16.3 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_33 PF13671.6 EGR28641.1 - 0.0049 17.0 0.0 0.0073 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGR28641.1 - 0.0065 16.2 0.0 0.032 14.0 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 EGR28641.1 - 0.013 15.8 0.0 0.14 12.4 0.0 2.3 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGR28641.1 - 0.02 14.8 0.2 1.4 8.8 0.1 2.5 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 EGR28641.1 - 0.036 13.3 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 EGR28641.1 - 0.038 13.4 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Cytidylate_kin2 PF13189.6 EGR28641.1 - 0.051 13.7 0.0 0.079 13.1 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase-like family AAA_24 PF13479.6 EGR28641.1 - 0.056 13.2 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGR28641.1 - 0.056 14.0 0.0 0.083 13.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EGR28641.1 - 0.069 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_17 PF13207.6 EGR28641.1 - 0.094 13.1 0.0 0.16 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.6 EGR28641.1 - 0.12 12.5 0.0 0.27 11.4 0.0 1.6 1 1 0 1 1 1 0 Sigma-54 interaction domain Viral_helicase1 PF01443.18 EGR28641.1 - 0.2 11.4 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TRAPP PF04051.16 EGR28645.1 - 2.4e-07 30.6 0.0 2.9e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component B2 PF11473.8 EGR28646.1 - 0.0031 17.3 1.4 0.0045 16.7 0.3 1.7 2 0 0 2 2 2 1 RNA binding protein B2 ApoO PF09769.9 EGR28646.1 - 0.12 12.4 0.8 0.23 11.4 0.3 1.8 1 1 1 2 2 2 0 Apolipoprotein O DUF573 PF04504.14 EGR28646.1 - 0.14 12.8 4.3 0.16 12.6 3.8 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF573 DUF842 PF05811.13 EGR28646.1 - 2.1 8.0 16.5 11 5.7 16.5 2.2 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF4407 PF14362.6 EGR28646.1 - 5.6 6.2 7.4 6.7 6.0 7.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 EGR28646.1 - 7.2 6.1 7.4 8.2 5.9 7.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit SPOUT_MTase_2 PF14419.6 EGR28647.1 - 0.24 10.8 1.7 0.42 10.0 0.1 2.2 2 0 0 2 2 2 0 AF2226-like SPOUT RNA Methylase fused to THUMP Adeno_PV PF03910.13 EGR28651.1 - 4.6 5.9 6.8 0.29 9.8 0.1 1.9 2 0 0 2 2 2 0 Adenovirus minor core protein PV DSPc PF00782.20 EGR28653.1 - 1e-09 38.3 0.7 1.3e-09 38.0 0.7 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain H_PPase PF03030.16 EGR28655.1 - 4.6e-16 58.6 27.9 3.5e-15 55.7 20.8 2.8 2 1 0 2 2 2 2 Inorganic H+ pyrophosphatase UMP1 PF05348.11 EGR28656.1 - 5.2e-13 49.2 0.0 6.3e-13 49.0 0.0 1.0 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 C2 PF00168.30 EGR28657.1 - 2.8e-05 24.3 0.1 3.8e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 C2 domain DUF3019 PF11456.8 EGR28657.1 - 0.09 13.3 0.1 0.12 12.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3019) EF-hand_1 PF00036.32 EGR28658.1 - 1.7e-31 105.4 17.3 2.3e-09 36.1 1.3 4.4 4 1 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGR28658.1 - 5.8e-31 106.8 9.3 3.6e-15 56.2 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGR28658.1 - 6.4e-25 86.8 9.2 2e-12 46.7 0.4 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 EGR28658.1 - 4.5e-24 82.3 10.2 2.5e-09 36.3 0.1 4.5 4 1 0 4 4 4 4 EF-hand domain EF-hand_9 PF14658.6 EGR28658.1 - 2.4e-16 59.8 0.2 6.5e-08 32.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGR28658.1 - 7.2e-11 41.1 15.8 7.4e-05 22.1 1.4 4.4 4 1 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 EGR28658.1 - 3.5e-05 24.1 0.5 0.12 12.7 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGR28658.1 - 4e-05 23.5 2.5 0.14 12.1 0.2 2.6 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand ERAP1_C PF11838.8 EGR28658.1 - 0.006 16.2 0.0 0.0073 15.9 0.0 1.1 1 0 0 1 1 1 1 ERAP1-like C-terminal domain DUF3008 PF11450.8 EGR28658.1 - 0.0071 16.5 0.8 0.015 15.4 0.2 1.8 2 0 0 2 2 1 1 Protein of unknwon function (DUF3008) EF-hand_14 PF17959.1 EGR28658.1 - 0.0077 16.6 1.4 2.7 8.4 0.0 2.6 1 1 0 2 2 2 1 EF-hand domain SUB1_ProdP9 PF18213.1 EGR28658.1 - 0.016 15.1 0.2 0.04 13.8 0.2 1.8 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 Acetyltransf_11 PF13720.6 EGR28658.1 - 0.022 15.2 0.5 0.57 10.7 0.1 2.2 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 DUF21 PF01595.20 EGR28658.1 - 0.027 14.2 1.9 0.24 11.1 0.6 2.1 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain Phage_TAC_10 PF10963.8 EGR28658.1 - 0.028 14.6 0.0 0.074 13.2 0.0 1.6 1 0 0 1 1 1 0 Phage tail assembly chaperone EF-hand_11 PF08976.11 EGR28658.1 - 0.029 15.2 0.2 1.1 10.2 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain SurA_N_2 PF13623.6 EGR28658.1 - 0.033 14.1 2.6 3.8 7.4 0.2 2.6 2 2 1 3 3 3 0 SurA N-terminal domain dCache_2 PF08269.11 EGR28658.1 - 0.036 13.3 0.9 0.41 9.8 0.2 2.2 1 1 1 2 2 2 0 Cache domain Caleosin PF05042.13 EGR28658.1 - 0.06 13.3 0.4 6.6 6.6 0.0 3.2 1 1 3 4 4 4 0 Caleosin related protein DUF853 PF05872.12 EGR28658.1 - 0.064 11.8 0.1 0.57 8.7 0.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) SRI PF08236.11 EGR28658.1 - 0.1 12.8 3.7 1.1 9.4 0.0 2.7 3 0 0 3 3 3 0 SRI (Set2 Rpb1 interacting) domain FlgD PF03963.14 EGR28658.1 - 0.11 12.8 0.1 0.24 11.7 0.1 1.8 1 1 0 1 1 1 0 Flagellar hook capping protein - N-terminal region Armet PF10208.9 EGR28658.1 - 0.13 12.2 0.2 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Degradation arginine-rich protein for mis-folding Peptidase_M24 PF00557.24 EGR28658.1 - 0.16 11.7 0.4 0.27 10.9 0.1 1.5 2 0 0 2 2 2 0 Metallopeptidase family M24 DUF3349 PF11829.8 EGR28658.1 - 0.34 11.7 1.4 8.3 7.3 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3349) SHOCT PF09851.9 EGR28658.1 - 0.61 9.9 10.2 0.25 11.1 0.7 3.8 3 0 0 3 3 3 0 Short C-terminal domain MgtE_N PF03448.17 EGR28658.1 - 0.96 10.1 6.7 0.56 10.8 1.2 2.6 3 0 0 3 3 3 0 MgtE intracellular N domain DUF2992 PF11208.8 EGR28658.1 - 1.3 9.3 5.1 2.3 8.5 0.2 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2992) YolD PF08863.10 EGR28658.1 - 9.6 6.3 7.8 18 5.5 0.2 3.3 3 1 0 3 3 3 0 YolD-like protein SRP54 PF00448.22 EGR28659.1 - 2.2e-52 177.6 0.1 2.2e-52 177.6 0.1 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 EGR28659.1 - 5e-20 72.6 22.1 9.7e-20 71.7 22.1 1.4 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 EGR28659.1 - 2.8e-10 40.3 0.6 2.8e-10 40.3 0.6 3.1 4 0 0 4 4 4 1 SRP54-type protein, helical bundle domain AAA_16 PF13191.6 EGR28659.1 - 0.00031 21.2 0.2 0.0037 17.7 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain CbiA PF01656.23 EGR28659.1 - 0.00066 19.7 0.7 0.0033 17.5 0.0 2.4 2 2 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 EGR28659.1 - 0.0024 17.6 0.0 0.0048 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGR28659.1 - 0.0026 18.1 0.2 0.033 14.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EGR28659.1 - 0.0063 16.4 4.1 1 9.2 0.0 3.2 3 0 0 3 3 3 2 NTPase MeaB PF03308.16 EGR28659.1 - 0.016 14.2 1.1 0.023 13.7 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF778 PF05608.12 EGR28659.1 - 4 7.8 6.7 5.6 7.3 0.0 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF778) U-box PF04564.15 EGR28660.1 - 1e-18 67.2 0.1 1.7e-18 66.5 0.1 1.4 1 0 0 1 1 1 1 U-box domain TPR_1 PF00515.28 EGR28660.1 - 1.2e-12 47.1 0.1 1.8e-06 27.5 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGR28660.1 - 7.8e-10 38.1 0.0 0.00013 21.8 0.0 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGR28660.1 - 1.1e-08 34.5 0.8 0.00021 21.2 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGR28660.1 - 9.8e-07 28.4 1.4 0.00011 21.8 0.1 3.8 3 1 1 4 4 4 1 TPR repeat zf-Nse PF11789.8 EGR28660.1 - 2.5e-06 27.2 0.2 1.4e-05 24.8 0.0 2.1 1 1 1 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit TPR_12 PF13424.6 EGR28660.1 - 1.6e-05 25.1 0.0 0.00016 21.9 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGR28660.1 - 7e-05 22.9 0.2 0.00082 19.6 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGR28660.1 - 0.00016 21.4 0.1 0.0015 18.4 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat zf-NOSIP PF15906.5 EGR28660.1 - 0.0004 20.5 0.4 0.0014 18.7 0.1 2.1 2 0 0 2 2 1 1 Zinc-finger of nitric oxide synthase-interacting protein MIT PF04212.18 EGR28660.1 - 0.00058 19.9 2.3 0.062 13.4 0.2 2.7 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain zf-RING_UBOX PF13445.6 EGR28660.1 - 0.0038 17.2 0.0 0.0089 16.0 0.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger ANAPC3 PF12895.7 EGR28660.1 - 0.0064 16.7 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGR28660.1 - 0.018 15.6 0.0 0.039 14.5 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGR28660.1 - 0.019 15.6 0.0 0.04 14.6 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4878 PF12870.7 EGR28660.1 - 0.11 12.8 1.7 0.11 12.7 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4878) SHNi-TPR PF10516.9 EGR28660.1 - 0.49 9.9 0.0 0.49 9.9 0.0 3.2 4 0 0 4 4 4 0 SHNi-TPR Peptidase_M16 PF00675.20 EGR28661.1 - 2.1e-29 102.4 0.9 8e-29 100.5 0.0 2.2 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) DUF5362 PF17319.2 EGR28661.1 - 0.0089 15.9 2.2 0.02 14.7 1.4 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5362) DUF5345 PF17280.2 EGR28661.1 - 0.1 12.6 0.7 0.32 11.0 0.7 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5345) CD20 PF04103.15 EGR28661.1 - 0.53 10.4 3.5 2.1 8.4 1.0 2.6 1 1 2 3 3 3 0 CD20-like family SHMT PF00464.19 EGR28663.1 - 1.3e-139 465.3 0.0 1.6e-139 465.0 0.0 1.1 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 EGR28663.1 - 0.12 11.7 0.0 0.29 10.4 0.0 1.6 1 0 0 1 1 1 0 Beta-eliminating lyase EF-hand_1 PF00036.32 EGR28664.1 - 1.5e-11 42.9 4.1 1.1e-05 24.6 0.5 2.7 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EGR28664.1 - 3.6e-11 42.0 6.9 1.2e-05 24.8 0.8 3.3 2 2 1 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EGR28664.1 - 5.1e-10 39.7 0.5 0.00011 22.5 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGR28664.1 - 1.4e-09 37.0 3.0 8e-06 25.1 0.3 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGR28664.1 - 6.1e-06 26.0 1.3 0.011 15.6 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGR28664.1 - 0.03 14.6 0.6 8.8 6.7 0.2 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region MORN PF02493.20 EGR28665.1 - 1.8e-50 165.9 69.9 1.2e-07 31.2 2.4 10.0 10 0 0 10 10 10 9 MORN repeat MFS_1 PF07690.16 EGR28666.1 - 3.6e-09 36.0 25.0 3.6e-09 36.0 25.0 2.8 1 1 1 2 2 2 2 Major Facilitator Superfamily CitMHS PF03600.16 EGR28666.1 - 0.93 8.6 14.7 8.3 5.5 0.0 2.6 1 1 1 2 2 2 0 Citrate transporter MFS_1 PF07690.16 EGR28667.1 - 2.8e-21 75.9 16.4 2.8e-21 75.9 16.4 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EGR28667.1 - 0.0001 21.3 12.4 0.00052 19.0 4.6 3.2 1 1 2 3 3 3 2 MFS_1 like family Tetraspanin PF00335.20 EGR28667.1 - 0.064 13.0 0.2 0.064 13.0 0.2 2.2 2 1 0 2 2 2 0 Tetraspanin family SyrA PF11089.8 EGR28667.1 - 2.2 8.4 9.2 5.2 7.2 0.5 3.5 3 0 0 3 3 3 0 Exopolysaccharide production repressor ParcG PF10274.9 EGR28669.1 - 6.1e-67 225.3 0.6 8.3e-65 218.3 0.6 2.3 1 1 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 EGR28669.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Peptidase_M24 PF00557.24 EGR28670.1 - 1.1e-19 71.0 0.0 1.2e-19 70.9 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 DHHC PF01529.20 EGR28672.1 - 1.2e-28 99.9 25.4 1.2e-28 99.9 25.4 2.6 2 1 0 2 2 2 1 DHHC palmitoyltransferase Actin PF00022.19 EGR28673.1 - 9.1e-112 373.6 0.0 2.3e-110 369.0 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGR28673.1 - 0.064 12.1 0.1 0.24 10.2 0.0 1.8 2 0 0 2 2 2 0 MreB/Mbl protein EF-hand_1 PF00036.32 EGR28674.1 - 0.00018 20.8 1.9 0.00036 19.9 0.3 2.5 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 EGR28674.1 - 0.00088 18.7 2.5 0.0037 16.7 0.3 2.7 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EGR28674.1 - 0.0011 19.3 0.4 0.0011 19.3 0.4 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 EGR28674.1 - 0.0015 18.4 0.1 0.0015 18.4 0.1 2.8 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_6 PF13405.6 EGR28674.1 - 0.0057 16.5 0.3 0.0057 16.5 0.3 3.4 4 0 0 4 4 4 1 EF-hand domain SHOCT PF09851.9 EGR28674.1 - 0.039 13.7 2.0 7.2 6.5 1.9 3.1 2 0 0 2 2 2 0 Short C-terminal domain Acetyltransf_11 PF13720.6 EGR28674.1 - 0.13 12.8 1.7 4.9 7.7 0.4 2.9 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 EF-hand_14 PF17959.1 EGR28674.1 - 0.93 9.9 9.1 0.1 13.0 0.5 3.2 3 0 0 3 3 3 0 EF-hand domain Asp_Arg_Hydrox PF05118.15 EGR28675.1 - 1.7e-40 138.5 0.2 2.7e-40 137.8 0.2 1.4 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Phage_hub_GP28 PF11110.8 EGR28675.1 - 0.098 12.6 0.1 0.87 9.5 0.0 2.0 2 0 0 2 2 2 0 Baseplate hub distal subunit XRN_N PF03159.18 EGR28676.1 - 2.8e-69 233.2 1.0 2.8e-69 233.2 1.0 4.0 3 1 0 3 3 3 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 EGR28676.1 - 3.2e-08 33.0 15.7 3.2e-08 33.0 15.7 3.9 3 1 0 3 3 3 2 Xrn1 helical domain DsrH PF04077.12 EGR28676.1 - 0.028 14.6 0.0 0.13 12.4 0.0 2.0 2 0 0 2 2 2 0 DsrH like protein Presenilin PF01080.17 EGR28676.1 - 8.1 5.1 27.1 0.061 12.1 11.6 2.7 3 0 0 3 3 3 0 Presenilin zf-LITAF-like PF10601.9 EGR28677.1 - 2.4e-11 43.7 3.6 2.4e-11 43.7 3.6 2.0 2 0 0 2 2 2 1 LITAF-like zinc ribbon domain TMEM154 PF15102.6 EGR28677.1 - 0.38 10.7 2.3 6.3 6.7 0.1 2.2 2 0 0 2 2 2 0 TMEM154 protein family Sigma_reg_N PF13800.6 EGR28677.1 - 9.1 6.6 9.5 0.34 11.2 0.7 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal ADK PF00406.22 EGR28678.1 - 2.6e-56 189.9 5.1 6e-45 153.0 0.0 5.7 4 3 1 5 5 5 3 Adenylate kinase AAA_17 PF13207.6 EGR28678.1 - 5.4e-38 130.5 0.1 2.7e-29 102.3 0.0 5.6 4 1 0 4 4 4 2 AAA domain AAA_18 PF13238.6 EGR28678.1 - 4.8e-19 69.2 0.1 3.7e-10 40.5 0.0 4.4 3 1 0 3 3 3 3 AAA domain AAA_33 PF13671.6 EGR28678.1 - 7.6e-10 39.1 0.0 0.00076 19.7 0.0 4.8 4 2 0 4 4 4 2 AAA domain AAA_28 PF13521.6 EGR28678.1 - 1.9e-07 31.5 0.0 1 9.6 0.0 4.4 4 0 0 4 4 4 2 AAA domain Zeta_toxin PF06414.12 EGR28678.1 - 0.00012 21.5 0.0 0.0083 15.4 0.0 2.8 3 0 0 3 3 3 1 Zeta toxin AAA_22 PF13401.6 EGR28678.1 - 0.0016 18.7 0.2 6.5 7.0 0.0 3.9 4 0 0 4 4 4 2 AAA domain Thymidylate_kin PF02223.17 EGR28678.1 - 0.0023 17.6 9.4 5.4 6.6 0.5 4.9 5 1 0 5 5 5 3 Thymidylate kinase T2SSE PF00437.20 EGR28678.1 - 0.014 14.5 0.0 1.6 7.7 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Rad17 PF03215.15 EGR28678.1 - 0.017 15.0 0.0 8 6.3 0.0 3.8 4 0 0 4 4 4 0 Rad17 P-loop domain NTPase_1 PF03266.15 EGR28678.1 - 0.03 14.2 0.1 0.54 10.2 0.0 2.8 3 0 0 3 3 3 0 NTPase AAA PF00004.29 EGR28678.1 - 0.099 13.1 0.0 23 5.4 0.0 3.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Cytidylate_kin PF02224.18 EGR28678.1 - 0.12 12.0 0.0 53 3.4 0.0 3.5 4 0 0 4 4 4 0 Cytidylate kinase Hydin_ADK PF17213.3 EGR28678.1 - 0.18 12.1 0.0 0.52 10.6 0.0 1.9 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Abhydrolase_1 PF00561.20 EGR28679.1 - 0.00023 20.9 0.1 0.0012 18.5 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGR28679.1 - 0.00034 20.0 0.0 0.00082 18.7 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 EGR28679.1 - 0.00064 19.7 0.7 0.8 9.6 0.0 2.8 1 1 2 3 3 3 2 BAAT / Acyl-CoA thioester hydrolase C terminal Asp2 PF16929.5 EGR28679.1 - 0.019 13.9 8.0 0.029 13.4 0.1 2.1 1 1 1 2 2 2 0 Accessory Sec system GspB-transporter CactinC_cactus PF09732.9 EGR28681.1 - 5e-54 181.6 10.0 5e-54 181.6 10.0 2.2 2 0 0 2 2 2 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 EGR28681.1 - 2.7e-29 102.3 13.7 2.7e-29 102.3 13.7 3.1 3 0 0 3 3 3 1 Conserved mid region of cactin DUF3385 PF11865.8 EGR28681.1 - 0.5 10.3 3.8 1.6 8.6 3.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) EDR1 PF14381.6 EGR28681.1 - 2.5 7.8 5.5 1.2 8.8 2.6 1.9 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 TUDOR PF00567.24 EGR28681.1 - 9.6 6.3 8.5 10 6.1 0.5 3.1 3 0 0 3 3 3 0 Tudor domain WD40 PF00400.32 EGR28682.1 - 5.4e-10 39.7 0.0 0.0038 18.0 0.0 3.1 3 0 0 3 3 3 2 WD domain, G-beta repeat PCRF PF03462.18 EGR28683.1 - 1.3e-45 155.6 0.0 2.3e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 EGR28683.1 - 2.2e-34 117.9 2.3 2.6e-34 117.6 0.0 2.2 2 1 0 2 2 2 1 RF-1 domain BspA_v PF18220.1 EGR28683.1 - 0.091 12.9 0.7 16 5.6 0.0 2.4 2 0 0 2 2 2 0 Adhesin BspA variable domain ubiquitin PF00240.23 EGR28684.1 - 1.2e-33 114.7 0.4 2.3e-33 113.8 0.3 1.5 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_L40e PF01020.17 EGR28684.1 - 1.8e-27 95.0 12.0 2.7e-27 94.4 12.0 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 EGR28684.1 - 2.8e-15 55.9 0.9 4e-15 55.4 0.5 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGR28684.1 - 8.9e-05 22.9 0.1 0.00035 21.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EGR28684.1 - 0.0062 16.9 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGR28684.1 - 0.0085 16.2 0.1 0.015 15.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EGR28684.1 - 0.025 14.5 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EGR28684.1 - 0.057 14.0 0.0 0.078 13.5 0.0 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EGR28684.1 - 0.064 13.3 1.0 6.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain SHIPPO-rpt PF07004.12 EGR28685.1 - 6e-08 33.2 27.3 0.017 16.0 0.2 6.7 6 1 0 6 6 6 4 Sperm-tail PG-rich repeat RabGAP-TBC PF00566.18 EGR28686.1 - 7.6e-43 146.7 10.9 7.6e-43 146.7 10.9 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Mhr1 PF12829.7 EGR28686.1 - 0.026 14.6 0.5 0.11 12.6 0.5 2.1 1 1 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination Cys_rich_FGFR PF00839.17 EGR28686.1 - 0.18 12.0 3.5 0.16 12.1 1.4 2.0 2 0 0 2 2 2 0 Cysteine rich repeat DUF2816 PF10992.8 EGR28687.1 - 1.4e-23 82.5 24.2 1.4e-23 82.5 24.2 4.7 3 1 2 5 5 5 2 Protein of unknown function (DUF2816) Retinin_C PF04527.12 EGR28687.1 - 1.3 9.3 13.7 7.4 6.9 4.9 2.8 2 0 0 2 2 2 0 Drosophila Retinin like protein DUF4091 PF13320.6 EGR28688.1 - 0.09 12.9 0.5 0.27 11.4 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4091) Patatin PF01734.22 EGR28689.1 - 6.3e-06 26.5 0.0 1.7e-05 25.1 0.0 1.6 2 0 0 2 2 2 1 Patatin-like phospholipase Ank_2 PF12796.7 EGR28689.1 - 0.031 14.9 0.0 0.065 13.8 0.0 1.5 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) zf-ZPR1 PF03367.13 EGR28690.1 - 8.2e-102 337.8 6.0 1.5e-52 177.7 2.1 2.4 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 EGR28690.1 - 0.0011 19.0 3.7 0.13 12.3 0.2 2.7 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TM1586_NiRdase PF14512.6 EGR28690.1 - 0.07 12.7 0.1 0.42 10.2 0.0 2.1 2 0 0 2 2 2 0 Putative TM nitroreductase DUF2120 PF09893.9 EGR28690.1 - 0.076 13.1 2.1 0.16 12.1 0.2 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) CorC_HlyC PF03471.17 EGR28690.1 - 0.16 12.0 0.7 0.8 9.8 0.0 2.4 3 0 0 3 3 3 0 Transporter associated domain Pkinase PF00069.25 EGR28691.1 - 3.9e-46 157.5 0.0 4.7e-46 157.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28691.1 - 1.9e-22 79.8 0.0 2.2e-22 79.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28691.1 - 4.8e-08 32.7 0.0 1.4e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR28691.1 - 7.2e-05 21.7 0.0 9.4e-05 21.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR28691.1 - 0.0057 16.6 0.0 0.0081 16.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGR28691.1 - 0.019 14.6 0.0 0.032 13.9 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGR28691.1 - 0.029 13.7 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_4 PF12799.7 EGR28692.1 - 5.3e-08 33.0 16.5 1.7e-06 28.2 8.3 5.9 3 1 2 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGR28692.1 - 6.4e-08 32.2 14.2 3.9e-06 26.5 8.2 4.0 2 1 1 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 EGR28692.1 - 0.029 14.4 8.7 3.7 7.9 1.8 4.4 4 0 0 4 4 4 0 Leucine Rich repeat Beach PF02138.18 EGR28693.1 - 1.9e-104 349.0 4.9 1.9e-104 349.0 4.9 3.0 3 0 0 3 3 3 2 Beige/BEACH domain PH_BEACH PF14844.6 EGR28693.1 - 3.7e-07 30.2 3.4 4.4e-05 23.5 0.1 3.4 3 1 0 3 3 3 2 PH domain associated with Beige/BEACH SplA PF11132.8 EGR28693.1 - 0.043 13.6 0.0 0.11 12.3 0.0 1.6 1 0 0 1 1 1 0 Transcriptional regulator protein (SplA) LRR_6 PF13516.6 EGR28694.1 - 2.2e-17 61.6 14.7 0.001 18.9 0.1 7.1 7 0 0 7 7 7 5 Leucine Rich repeat LRR_1 PF00560.33 EGR28694.1 - 0.002 18.4 11.2 12 6.9 0.1 6.4 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_4 PF12799.7 EGR28694.1 - 0.0088 16.4 24.6 0.049 14.1 4.6 5.3 2 2 1 4 4 4 3 Leucine Rich repeats (2 copies) ALS2CR8 PF15299.6 EGR28694.1 - 0.026 14.4 4.7 0.047 13.6 4.7 1.3 1 0 0 1 1 1 0 Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 DUF1828 PF08861.10 EGR28694.1 - 0.048 13.9 0.4 0.27 11.6 0.4 2.3 1 0 0 1 1 1 0 Domain of unknown function DUF1828 AMP-binding PF00501.28 EGR28695.1 - 3.4e-23 81.9 0.0 4.4e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGR28695.1 - 3.5e-19 69.6 0.1 5.6e-19 68.9 0.1 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SEP PF08059.13 EGR28696.1 - 1.3e-23 83.3 0.4 4e-23 81.8 0.1 2.0 2 0 0 2 2 2 1 SEP domain UBX PF00789.20 EGR28696.1 - 0.00024 21.2 0.0 0.0006 20.0 0.0 1.7 1 0 0 1 1 1 1 UBX domain TssD PF17642.1 EGR28696.1 - 0.014 15.2 0.3 0.045 13.6 0.1 1.8 2 0 0 2 2 2 0 Hemolysin coregulated protein Hcp (TssD) DUF4314 PF14192.6 EGR28696.1 - 0.025 14.5 0.0 2.8 7.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4314) PDGLE PF13190.6 EGR28696.1 - 0.05 13.5 0.0 0.38 10.7 0.0 2.2 2 0 0 2 2 2 0 PDGLE domain eIF-5a PF01287.20 EGR28697.1 - 0.036 14.2 2.3 3 8.0 0.6 2.5 2 1 0 2 2 2 0 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Fer4_13 PF13370.6 EGR28697.1 - 0.077 13.5 0.3 0.13 12.8 0.3 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain of Ferredoxin I VCBS PF13517.6 EGR28698.1 - 2.3e-14 53.7 10.9 4.9e-07 30.2 0.8 4.2 2 1 2 4 4 4 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGR28698.1 - 1.5e-07 31.4 6.5 4.5 7.5 0.0 5.2 5 0 0 5 5 5 4 FG-GAP repeat TPR_21 PF09976.9 EGR28699.1 - 0.088 12.5 0.1 0.11 12.2 0.1 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain DUF4541 PF15074.6 EGR28700.1 - 0.0048 17.5 2.6 0.0053 17.3 0.1 2.1 1 1 0 2 2 2 1 Domain of unknown function (DUF4541) FAM183 PF14886.6 EGR28700.1 - 0.048 14.4 7.4 1.2 9.9 7.3 2.5 1 1 0 1 1 1 0 FAM183A and FAM183B related Ras PF00071.22 EGR28701.1 - 1.5e-51 174.3 2.9 1.8e-51 174.0 2.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR28701.1 - 6.2e-33 113.6 1.1 8.5e-33 113.1 1.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR28701.1 - 6.2e-19 68.1 2.1 7.1e-19 67.9 2.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGR28701.1 - 8.1e-08 31.9 1.9 1e-07 31.6 1.9 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGR28701.1 - 2.7e-07 30.6 0.4 3.9e-07 30.2 0.4 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGR28701.1 - 8.4e-05 22.5 6.1 0.025 14.5 0.3 2.4 1 1 2 3 3 3 2 RsgA GTPase SRPRB PF09439.10 EGR28701.1 - 0.00026 20.5 0.4 0.00031 20.2 0.4 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EGR28701.1 - 0.00037 20.1 1.5 0.0011 18.6 1.5 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EGR28701.1 - 0.0019 18.6 0.0 0.0034 17.8 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EGR28701.1 - 0.0058 16.4 0.9 0.012 15.3 0.9 1.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGR28701.1 - 0.007 16.1 0.4 0.029 14.1 0.1 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain DAP3 PF10236.9 EGR28701.1 - 0.0078 15.4 0.2 0.022 14.0 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 AAA_22 PF13401.6 EGR28701.1 - 0.0086 16.4 0.1 0.043 14.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.20 EGR28701.1 - 0.01 15.0 6.2 0.16 11.1 0.2 2.2 1 1 1 2 2 2 0 G-protein alpha subunit Septin PF00735.18 EGR28701.1 - 0.023 14.0 4.3 0.034 13.4 0.2 2.1 1 1 0 2 2 2 0 Septin ABC_tran PF00005.27 EGR28701.1 - 0.026 15.0 1.7 0.044 14.3 1.7 1.5 1 1 0 1 1 1 0 ABC transporter AAA_5 PF07728.14 EGR28701.1 - 0.079 13.0 0.1 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) ATP-synt_ab PF00006.25 EGR28701.1 - 0.12 12.0 0.1 0.95 9.1 0.1 1.9 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain Synaptobrevin PF00957.21 EGR28702.1 - 4.2e-25 87.4 5.4 7.9e-25 86.5 5.4 1.5 1 0 0 1 1 1 1 Synaptobrevin LMBR1 PF04791.16 EGR28702.1 - 0.013 14.5 0.5 0.014 14.4 0.5 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF730 PF05325.11 EGR28702.1 - 0.036 14.1 1.1 0.053 13.5 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF730) Hat1_N PF10394.9 EGR28703.1 - 2.5e-24 86.3 12.9 2.5e-24 86.3 12.9 2.2 2 1 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.7 EGR28703.1 - 0.00058 19.8 0.3 0.0018 18.2 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGR28703.1 - 0.0062 16.8 0.0 0.014 15.6 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Sec1 PF00995.23 EGR28704.1 - 1.3e-65 222.8 18.4 1.7e-65 222.4 18.4 1.0 1 0 0 1 1 1 1 Sec1 family YozE_SAM_like PF06855.12 EGR28704.1 - 0.017 15.3 0.1 0.15 12.2 0.0 2.7 2 0 0 2 2 2 0 YozE SAM-like fold DASH_Dad4 PF08650.10 EGR28704.1 - 0.48 10.4 0.1 0.48 10.4 0.1 3.9 4 0 0 4 4 4 0 DASH complex subunit Dad4 IFT20 PF14931.6 EGR28705.1 - 1e-36 125.7 17.9 1.1e-36 125.5 17.9 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B, subunit 20 DUF724 PF05266.14 EGR28705.1 - 0.018 14.8 13.7 0.021 14.7 13.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF1664 PF07889.12 EGR28705.1 - 0.092 12.8 7.9 0.12 12.4 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF3450 PF11932.8 EGR28705.1 - 0.15 11.3 11.0 0.19 11.0 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Sec8_exocyst PF04048.14 EGR28705.1 - 0.18 11.7 8.5 0.23 11.3 8.5 1.2 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain NPV_P10 PF05531.12 EGR28705.1 - 0.19 12.2 3.9 3.4 8.2 0.5 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Seryl_tRNA_N PF02403.22 EGR28705.1 - 0.24 11.7 15.3 0.1 12.8 12.5 1.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMCO5 PF14992.6 EGR28705.1 - 0.26 10.8 18.1 0.3 10.6 18.1 1.0 1 0 0 1 1 1 0 TMCO5 family DUF4665 PF15679.5 EGR28705.1 - 0.5 11.0 12.3 1.3 9.7 2.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) Exonuc_VII_L PF02601.15 EGR28705.1 - 1.1 8.7 7.9 1.2 8.6 7.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3837 PF12939.7 EGR28705.1 - 1.2 9.6 9.0 0.25 11.8 1.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3837) SpoIISA_toxin PF14171.6 EGR28705.1 - 1.3 8.7 6.7 1.5 8.5 6.7 1.2 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system APG6_N PF17675.1 EGR28705.1 - 4.3 7.9 19.8 15 6.1 19.8 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region Atg14 PF10186.9 EGR28705.1 - 5.2 6.1 14.1 6.6 5.7 14.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMPIT PF07851.13 EGR28705.1 - 5.3 6.2 10.1 7.4 5.7 10.1 1.3 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 EGR28705.1 - 6.3 4.6 11.3 7.5 4.3 11.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family 2-oxoacid_dh PF00198.23 EGR28706.1 - 1.1e-20 74.1 0.1 4.1e-12 46.0 0.1 2.2 2 0 0 2 2 2 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Pkinase PF00069.25 EGR28707.1 - 1.5e-68 231.0 3.2 1.5e-68 231.0 3.2 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28707.1 - 2.2e-35 122.2 0.9 4.1e-35 121.3 0.9 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR28707.1 - 2.6e-05 23.7 1.8 5e-05 22.7 1.8 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGR28707.1 - 0.015 15.0 0.3 0.07 12.7 0.1 2.2 2 2 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGR28707.1 - 0.023 13.5 0.7 0.051 12.3 0.1 1.8 1 1 1 2 2 2 0 Fungal protein kinase Mrpl_C PF18502.1 EGR28707.1 - 1.1 9.6 8.2 0.21 11.9 1.1 3.1 3 1 1 4 4 4 0 54S ribosomal protein L8 C-terminal domain DEAD PF00270.29 EGR28708.1 - 6.9e-42 143.2 0.0 7.7e-41 139.8 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR28708.1 - 1.8e-28 99.1 0.0 1.8e-28 99.1 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain TFIIA PF03153.13 EGR28708.1 - 0.046 13.7 24.6 0.07 13.1 24.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NAD_binding_6 PF08030.12 EGR28709.1 - 0.045 13.9 5.3 0.061 13.4 5.3 1.4 1 1 0 1 1 1 0 Ferric reductase NAD binding domain UPF0172 PF03665.13 EGR28710.1 - 4.3e-08 33.4 0.2 4.5e-08 33.4 0.2 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) RRM_1 PF00076.22 EGR28711.1 - 2.2e-12 46.6 0.0 4.1e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 EGR28711.1 - 4.2e-07 29.8 1.0 6.9e-07 29.1 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle Collagen PF01391.18 EGR28711.1 - 1e-05 25.2 9.2 2.3e-05 24.1 9.2 1.5 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) RRM_3 PF08777.11 EGR28711.1 - 0.0031 17.5 0.0 0.0031 17.5 0.0 2.2 2 0 0 2 2 2 1 RNA binding motif RRM_occluded PF16842.5 EGR28711.1 - 0.098 12.5 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif zf-CCHC_2 PF13696.6 EGR28711.1 - 0.21 11.4 0.4 0.36 10.7 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle NOG1_N PF17835.1 EGR28712.1 - 3.8e-50 170.0 0.0 3.8e-50 170.0 0.0 2.5 2 1 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 EGR28712.1 - 8.6e-28 95.9 0.7 2.6e-27 94.3 0.7 1.9 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) NOGCT PF08155.11 EGR28712.1 - 1.5e-25 88.9 0.4 3.8e-25 87.6 0.4 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain MMR_HSR1 PF01926.23 EGR28712.1 - 1.1e-19 70.5 0.0 4.1e-19 68.8 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGR28712.1 - 3.2e-14 52.8 0.4 6e-14 51.9 0.4 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B Ras PF00071.22 EGR28712.1 - 3.7e-05 23.4 0.3 9.5e-05 22.1 0.3 1.7 1 0 0 1 1 1 1 Ras family RsgA_GTPase PF03193.16 EGR28712.1 - 0.016 15.1 11.1 0.38 10.6 0.0 3.9 4 1 0 4 4 4 0 RsgA GTPase AAA_18 PF13238.6 EGR28712.1 - 0.85 10.2 0.0 0.85 10.2 0.0 4.0 3 2 1 4 4 3 0 AAA domain DUF572 PF04502.13 EGR28712.1 - 4.1 6.9 23.0 6.5 6.3 23.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) LMBR1 PF04791.16 EGR28712.1 - 4.4 6.1 8.9 7.3 5.4 8.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein PBP1_TM PF14812.6 EGR28712.1 - 7.7 7.0 13.2 5.9 7.3 6.2 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Exonuc_VII_L PF02601.15 EGR28712.1 - 9.6 5.7 12.1 27 4.2 12.1 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit OFeT_1 PF16955.5 EGR28713.1 - 0.09 12.5 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 Ferrous iron uptake permease, iron-lead transporter TPR_2 PF07719.17 EGR28714.1 - 3.7e-38 126.6 25.7 1.9e-07 30.7 0.4 10.6 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_1 PF00515.28 EGR28714.1 - 4.1e-37 124.5 28.8 7.3e-07 28.8 0.0 11.2 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_8 PF13181.6 EGR28714.1 - 1e-25 87.7 24.9 0.00026 21.0 0.2 9.8 10 0 0 10 10 10 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR28714.1 - 7.9e-23 80.5 31.3 2.2e-15 56.7 2.8 6.5 3 1 5 8 8 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EGR28714.1 - 1.3e-22 79.9 9.9 3.3e-06 27.3 0.1 8.2 5 3 3 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGR28714.1 - 4.5e-21 75.1 5.1 5e-05 23.7 0.3 7.7 7 1 1 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.6 EGR28714.1 - 3.7e-19 69.1 0.4 1.6e-06 28.6 0.0 7.0 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGR28714.1 - 1e-17 63.3 0.1 0.25 12.2 0.0 9.3 5 1 4 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGR28714.1 - 1.5e-16 59.8 20.3 5.4e-06 26.0 0.2 8.7 5 4 4 9 9 9 4 TPR repeat TPR_7 PF13176.6 EGR28714.1 - 8.7e-16 56.7 0.2 0.5 10.5 0.0 8.4 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGR28714.1 - 4.1e-09 36.5 12.9 1.2 9.9 0.0 8.9 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGR28714.1 - 1.1e-08 34.8 18.0 3.2 8.3 0.4 9.3 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGR28714.1 - 2e-08 34.3 0.0 0.0027 17.8 0.0 4.7 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGR28714.1 - 3.5e-06 26.7 4.1 0.43 10.5 0.1 6.5 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGR28714.1 - 0.0038 16.5 5.4 0.071 12.3 0.1 4.0 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_3 PF07720.12 EGR28714.1 - 0.17 11.9 0.0 0.17 11.9 0.0 5.1 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF2225 PF09986.9 EGR28714.1 - 0.18 11.5 20.1 0.32 10.7 0.5 4.0 2 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) VPR PF00522.18 EGR28714.1 - 0.36 10.9 6.6 0.34 11.0 0.8 3.4 2 1 1 3 3 3 0 VPR/VPX protein Tox-HNH-HHH PF15637.6 EGR28714.1 - 0.68 10.1 2.7 7.6 6.7 0.1 2.5 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif MetOD1 PF18546.1 EGR28714.1 - 0.73 9.8 5.3 0.18 11.8 0.8 2.2 2 0 0 2 2 2 0 Metanogen output domain 1 H_PPase PF03030.16 EGR28715.1 - 2.2e-253 842.7 19.9 2.5e-253 842.5 19.9 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase PAP2_3 PF14378.6 EGR28715.1 - 0.024 14.3 0.1 0.28 10.9 0.0 2.4 2 0 0 2 2 2 0 PAP2 superfamily L51_S25_CI-B8 PF05047.16 EGR28717.1 - 9.5e-06 25.4 0.7 1.9e-05 24.5 0.7 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain cNMP_binding PF00027.29 EGR28719.1 - 4.2e-09 36.3 0.0 5.5e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF4217 PF13959.6 EGR28719.1 - 0.059 13.6 0.0 0.077 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) UPF0228 PF05727.11 EGR28719.1 - 0.1 12.4 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0228) DUF3072 PF11272.8 EGR28719.1 - 0.15 12.0 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) Ion_trans_2 PF07885.16 EGR28720.1 - 6.9e-13 48.4 4.9 1.3e-12 47.5 4.9 1.4 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGR28720.1 - 4.9e-06 25.9 11.9 6.8e-06 25.5 11.9 1.2 1 0 0 1 1 1 1 Ion transport protein DUF2069 PF09842.9 EGR28720.1 - 0.024 14.8 1.5 0.024 14.8 0.1 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2069) Styelin PF17562.2 EGR28720.1 - 0.081 13.3 0.7 0.23 11.9 0.7 1.7 1 0 0 1 1 1 0 Styelin DUF3137 PF11335.8 EGR28720.1 - 0.17 11.9 6.8 0.073 13.0 3.9 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3137) CaMBD PF02888.16 EGR28720.1 - 0.27 11.4 5.8 0.64 10.3 5.8 1.6 1 0 0 1 1 1 0 Calmodulin binding domain PGG PF13962.6 EGR28720.1 - 0.72 9.7 7.3 0.15 11.9 1.8 2.2 1 1 1 2 2 2 0 Domain of unknown function Pkinase PF00069.25 EGR28721.1 - 1.6e-70 237.5 6.2 3.9e-70 236.2 6.2 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28721.1 - 9.9e-41 139.7 2.2 1.5e-40 139.1 2.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR28721.1 - 3.4e-06 26.6 2.0 6.4e-06 25.7 2.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_7 PF13499.6 EGR28721.1 - 0.0016 18.9 2.0 0.0029 18.0 0.5 2.3 2 0 0 2 2 2 1 EF-hand domain pair APH PF01636.23 EGR28721.1 - 0.0051 16.8 0.1 0.18 11.7 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family EF-hand_5 PF13202.6 EGR28721.1 - 0.034 13.6 0.0 0.13 11.8 0.0 2.1 1 0 0 1 1 1 0 EF hand EF-hand_6 PF13405.6 EGR28721.1 - 0.04 13.8 0.1 0.04 13.8 0.1 3.1 4 0 0 4 4 4 0 EF-hand domain EF-hand_1 PF00036.32 EGR28721.1 - 0.068 12.8 0.1 0.068 12.8 0.1 2.4 2 0 0 2 2 2 0 EF hand Ras PF00071.22 EGR28722.1 - 4.1e-59 198.8 2.5 4.6e-59 198.6 2.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR28722.1 - 2.8e-36 124.4 0.3 4.8e-36 123.6 0.3 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR28722.1 - 9.3e-19 67.5 0.6 1e-18 67.4 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGR28722.1 - 1.5e-08 34.7 0.2 0.0032 17.4 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGR28722.1 - 4.6e-08 33.1 0.1 6.9e-08 32.6 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGR28722.1 - 5.3e-06 26.0 0.8 7.3e-06 25.5 0.8 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGR28722.1 - 2.4e-05 24.0 0.7 9.7e-05 22.0 0.7 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGR28722.1 - 7.4e-05 22.3 0.1 9.9e-05 21.8 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EGR28722.1 - 0.0036 17.6 0.0 0.015 15.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGR28722.1 - 0.012 16.0 0.0 0.021 15.2 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 EGR28722.1 - 0.029 13.9 0.0 0.44 10.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region PRORP PF16953.5 EGR28722.1 - 0.054 13.0 0.4 0.067 12.7 0.4 1.1 1 0 0 1 1 1 0 Protein-only RNase P AAA_29 PF13555.6 EGR28722.1 - 0.061 13.1 0.1 0.2 11.4 0.1 1.8 2 0 0 2 2 1 0 P-loop containing region of AAA domain Ldh_1_N PF00056.23 EGR28722.1 - 0.069 13.2 0.4 0.32 11.1 0.4 2.0 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain ABC_tran PF00005.27 EGR28722.1 - 0.081 13.4 1.1 0.12 12.9 1.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_21 PF13304.6 EGR28722.1 - 0.13 12.1 1.2 0.18 11.6 1.2 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 EGR28722.1 - 0.16 11.5 1.8 5.6 6.5 0.4 2.2 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PWWP PF00855.17 EGR28723.1 - 9.5e-07 29.1 7.0 9.5e-07 29.1 7.0 3.7 2 2 1 3 3 3 1 PWWP domain Peptidase_M8 PF01457.16 EGR28725.1 - 2.9e-30 105.5 0.8 6.6e-17 61.4 0.0 3.9 2 2 3 5 5 5 3 Leishmanolysin EGF_Tenascin PF18720.1 EGR28725.1 - 4.1e-07 29.9 8.3 4.1e-07 29.9 8.3 4.2 3 0 0 3 3 3 1 Tenascin EGF domain DUF2716 PF10898.8 EGR28725.1 - 0.059 13.7 0.3 4.2 7.7 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2716) EGF_Tenascin PF18720.1 EGR28726.1 - 8.3e-08 32.1 7.9 8.3e-08 32.1 7.9 2.7 2 0 0 2 2 2 1 Tenascin EGF domain EGF_2 PF07974.13 EGR28726.1 - 0.023 15.0 17.9 0.023 15.0 17.9 4.7 3 2 1 4 4 4 0 EGF-like domain Furin-like PF00757.20 EGR28726.1 - 0.37 10.6 39.1 2.8 7.8 19.4 3.2 2 1 1 3 3 3 0 Furin-like cysteine rich region GBP PF02263.19 EGR28728.1 - 6.9e-59 199.2 5.8 6.9e-59 199.2 5.8 2.0 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 EGR28728.1 - 2.6e-05 24.3 1.3 6e-05 23.1 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase GRIN_C PF15235.6 EGR28728.1 - 3.7 7.8 7.7 4.1 7.6 3.4 2.4 2 0 0 2 2 2 0 G protein-regulated inducer of neurite outgrowth C-terminus GTP_EFTU PF00009.27 EGR28728.1 - 4.6 6.7 0.0 4.6 6.7 0.0 3.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Hydrolase_4 PF12146.8 EGR28729.1 - 4.7e-48 163.5 0.0 6.4e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR28729.1 - 2.9e-15 56.6 0.3 1.1e-12 48.2 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGR28729.1 - 4.5e-08 32.8 0.1 6.1e-06 25.9 0.1 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 EGR28729.1 - 0.00019 21.2 0.0 0.00057 19.6 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 EGR28729.1 - 0.00022 21.9 0.0 0.00031 21.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.12 EGR28729.1 - 0.0016 17.3 1.2 0.0016 17.3 0.1 1.5 2 0 0 2 2 2 1 Serine carboxypeptidase S28 Peptidase_S15 PF02129.18 EGR28729.1 - 0.0021 17.7 0.0 0.0062 16.2 0.0 1.8 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Chlorophyllase2 PF12740.7 EGR28729.1 - 0.0035 16.3 0.1 0.006 15.5 0.1 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_5 PF12695.7 EGR28729.1 - 0.033 13.9 0.0 0.077 12.8 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Esterase_phd PF10503.9 EGR28729.1 - 0.15 11.5 0.0 0.42 10.1 0.0 1.8 2 1 0 2 2 2 0 Esterase PHB depolymerase Tannase PF07519.11 EGR28729.1 - 0.16 10.8 0.0 0.34 9.8 0.0 1.5 2 0 0 2 2 2 0 Tannase and feruloyl esterase RBD-FIP PF09457.10 EGR28730.1 - 0.015 15.2 0.5 0.044 13.7 0.5 1.8 1 0 0 1 1 1 0 FIP domain LuxT_C PF18285.1 EGR28730.1 - 0.016 15.8 1.1 0.039 14.5 0.8 1.9 1 1 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain Gp_dh_N PF00044.24 EGR28730.1 - 0.018 15.4 0.6 0.046 14.1 0.6 1.7 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Uricase PF01014.18 EGR28730.1 - 0.11 12.8 0.0 0.13 12.6 0.0 1.4 1 1 0 1 1 1 0 Uricase PX PF00787.24 EGR28730.1 - 0.74 9.8 7.1 0.093 12.7 2.4 1.9 2 2 0 2 2 2 0 PX domain WD40 PF00400.32 EGR28731.1 - 1.2e-19 70.2 3.7 0.011 16.5 0.0 8.0 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR28731.1 - 2.9e-10 40.3 0.1 0.022 15.0 0.0 5.5 3 2 3 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGR28731.1 - 0.016 13.9 0.4 3.4 6.2 0.0 2.7 2 1 0 2 2 2 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EGR28731.1 - 0.034 13.1 0.0 0.062 12.2 0.0 1.5 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain Kelch_1 PF01344.25 EGR28733.1 - 5e-17 61.2 0.9 1.5e-09 37.3 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 EGR28733.1 - 3.4e-13 49.4 0.0 4.9e-05 23.3 0.0 4.2 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EGR28733.1 - 1.1e-07 31.7 2.5 0.0073 16.3 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_6 PF13964.6 EGR28733.1 - 1.1e-07 31.8 0.3 0.00034 20.8 0.0 3.9 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 EGR28733.1 - 4.1e-06 26.6 0.2 0.0093 15.9 0.0 3.3 3 0 0 3 3 3 2 Kelch motif Kelch_3 PF13415.6 EGR28733.1 - 2.7e-05 24.3 0.0 0.011 16.0 0.0 3.2 4 0 0 4 4 4 1 Galactose oxidase, central domain zf-B_box PF00643.24 EGR28733.1 - 0.0021 18.2 10.6 0.004 17.3 10.6 1.4 1 0 0 1 1 1 1 B-box zinc finger ABC_tran PF00005.27 EGR28734.1 - 4.9e-49 166.4 7.1 3.9e-30 105.1 0.4 3.2 3 1 0 3 3 2 2 ABC transporter ABC_membrane PF00664.23 EGR28734.1 - 6.9e-48 163.7 52.2 3.1e-25 89.4 22.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EGR28734.1 - 6.1e-09 35.6 19.1 0.00018 21.0 2.7 4.9 3 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGR28734.1 - 1.8e-05 24.4 0.4 0.25 11.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGR28734.1 - 8.8e-05 22.6 0.4 0.12 12.4 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 EGR28734.1 - 0.0049 16.7 17.5 3.1 7.5 0.2 5.3 4 2 1 6 6 5 3 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 EGR28734.1 - 0.0075 15.4 0.0 1.4 8.0 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 EGR28734.1 - 0.0078 15.8 0.3 5.6 6.5 0.0 2.7 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 EGR28734.1 - 0.0078 16.1 0.6 1.8 8.5 0.1 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 EGR28734.1 - 0.0087 15.6 3.0 1.6 8.2 0.0 3.0 3 0 0 3 3 3 2 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 EGR28734.1 - 0.0091 15.0 0.4 1.2 8.0 0.3 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 EGR28734.1 - 0.014 15.8 0.0 3.6 7.9 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EGR28734.1 - 0.016 15.5 1.1 7.8 6.8 0.1 3.3 2 1 0 2 2 2 0 AAA domain PRK PF00485.18 EGR28734.1 - 0.055 13.2 0.3 3.8 7.2 0.1 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family CbiA PF01656.23 EGR28734.1 - 0.13 12.3 0.0 0.44 10.6 0.0 1.9 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Zeta_toxin PF06414.12 EGR28734.1 - 0.14 11.5 0.0 16 4.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DUF87 PF01935.17 EGR28734.1 - 0.48 10.5 11.5 0.18 11.9 0.6 3.9 3 1 1 4 4 4 0 Helicase HerA, central domain AAA_18 PF13238.6 EGR28734.1 - 0.79 10.3 4.7 3.6 8.1 0.0 3.5 4 0 0 4 4 3 0 AAA domain Dynamin_N PF00350.23 EGR28734.1 - 1.2 9.2 11.8 0.15 12.1 0.2 3.6 3 0 0 3 3 3 0 Dynamin family DnaJ_C PF01556.18 EGR28735.1 - 2.2e-33 115.4 0.3 3.9e-33 114.6 0.3 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGR28735.1 - 8.1e-26 89.9 4.0 1.7e-25 88.9 4.0 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGR28735.1 - 2.3e-14 53.5 13.6 4.2e-14 52.6 13.6 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGR28735.1 - 8.2e-06 25.7 6.7 0.0024 17.8 1.8 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein zinc_ribbon_9 PF14369.6 EGR28735.1 - 0.028 14.7 6.3 0.6 10.4 0.8 2.7 1 1 1 2 2 2 0 zinc-ribbon RPT PF13446.6 EGR28735.1 - 0.081 12.9 0.0 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 A repeated domain in UCH-protein Lar_restr_allev PF14354.6 EGR28735.1 - 0.55 10.6 10.3 0.86 10.0 5.5 2.8 2 1 0 2 2 2 0 Restriction alleviation protein Lar FdhE PF04216.12 EGR28735.1 - 0.56 10.0 3.7 1 9.2 3.7 1.4 1 0 0 1 1 1 0 Protein involved in formate dehydrogenase formation zf-RING_10 PF16685.5 EGR28735.1 - 2.2 8.5 6.8 0.2 11.8 1.6 1.9 1 1 1 2 2 2 0 zinc RING finger of MSL2 zinc_ribbon_2 PF13240.6 EGR28735.1 - 2.3 8.0 5.5 18 5.2 0.8 2.8 1 1 1 2 2 2 0 zinc-ribbon domain zf-C3HC4_3 PF13920.6 EGR28735.1 - 8.6 6.3 7.8 17 5.4 0.3 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Histone PF00125.24 EGR28736.1 - 9.2e-51 171.6 2.8 1.3e-50 171.2 2.8 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 EGR28736.1 - 0.00024 21.7 2.2 0.00033 21.3 2.2 1.2 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EGR28736.1 - 0.00031 20.8 1.3 0.00038 20.5 0.1 1.8 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGR28736.1 - 0.0024 18.2 0.0 0.0044 17.4 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EGR28736.1 - 0.08 13.0 0.6 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit EMP24_GP25L PF01105.24 EGR28737.1 - 4.6e-21 75.6 4.6 8.5e-21 74.7 4.6 1.4 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CENP-T_C PF15511.6 EGR28737.1 - 7.7e-09 35.6 0.1 1.4e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGR28737.1 - 0.00049 20.4 0.1 0.0014 18.9 0.1 1.8 1 0 0 1 1 1 1 CENP-S protein TAF PF02969.17 EGR28737.1 - 0.00071 19.7 0.1 0.0017 18.5 0.1 1.7 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EGR28737.1 - 0.0021 18.3 0.0 0.0037 17.5 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGR28737.1 - 0.0023 18.3 0.1 0.0023 18.3 0.1 1.9 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 EGR28737.1 - 0.0074 16.3 0.1 0.019 15.0 0.1 1.6 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 EGR28737.1 - 0.012 15.7 0.1 0.022 14.8 0.1 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Ribosomal_L27A PF00828.19 EGR28737.1 - 1.3 9.7 8.7 0.48 11.1 2.9 2.3 1 1 1 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF4456 PF14644.6 EGR28738.1 - 0.00053 19.7 0.3 0.00053 19.7 0.3 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4456) DUF4296 PF14129.6 EGR28738.1 - 0.038 14.6 0.7 0.038 14.6 0.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4296) Pro_isomerase PF00160.21 EGR28739.1 - 6.1e-48 163.1 0.4 6.9e-48 162.9 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 2-oxoacid_dh PF00198.23 EGR28740.1 - 2.4e-15 56.6 0.7 4.4e-13 49.2 0.0 2.2 2 0 0 2 2 2 2 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Pkinase PF00069.25 EGR28741.1 - 6.1e-70 235.6 1.0 6.9e-70 235.4 1.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28741.1 - 4.6e-37 127.7 0.1 5.5e-37 127.5 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28741.1 - 2.5e-06 27.0 0.1 4.2e-06 26.3 0.1 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR28741.1 - 9.2e-05 21.9 0.6 0.00013 21.4 0.6 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR28741.1 - 0.00014 20.8 0.0 0.00025 20.0 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR28741.1 - 0.0083 16.1 0.0 0.014 15.3 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGR28741.1 - 0.0092 15.6 3.1 0.024 14.2 3.1 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 EGR28741.1 - 0.029 13.3 4.5 0.048 12.6 4.5 1.3 1 1 0 1 1 1 0 Haspin like kinase domain PLDc PF00614.22 EGR28742.1 - 3.5e-15 55.5 4.1 4.6e-08 32.9 0.2 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EGR28742.1 - 1.2e-13 51.1 6.5 1.6e-08 34.5 0.3 3.9 3 1 0 3 3 3 2 PLD-like domain PH PF00169.29 EGR28742.1 - 0.18 12.4 0.2 0.18 12.4 0.2 3.9 5 0 0 5 5 5 0 PH domain zf-HC5HC2H_2 PF13832.6 EGR28743.1 - 1.3e-21 76.8 19.1 7.8e-20 71.1 7.3 3.5 3 0 0 3 3 3 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EGR28743.1 - 2.5e-19 69.3 9.5 2.5e-19 69.3 9.5 3.4 3 1 0 4 4 4 1 PHD-like zinc-binding domain PHD_2 PF13831.6 EGR28743.1 - 1e-12 47.4 3.7 1e-12 47.4 3.7 3.5 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 EGR28743.1 - 2e-08 34.0 6.6 2e-08 34.0 6.6 3.8 4 1 0 4 4 4 2 PHD-finger Prok-RING_1 PF14446.6 EGR28743.1 - 6.7e-05 22.7 3.2 6.7e-05 22.7 3.2 3.5 3 0 0 3 3 3 2 Prokaryotic RING finger family 1 C1_2 PF03107.16 EGR28743.1 - 0.0075 16.6 3.5 0.0075 16.6 3.5 3.9 4 1 0 4 4 4 2 C1 domain DUF2318 PF10080.9 EGR28743.1 - 5.9 7.1 19.3 0.46 10.6 2.8 3.8 4 1 0 4 4 4 0 Predicted membrane protein (DUF2318) RabGAP-TBC PF00566.18 EGR28744.1 - 1e-27 97.3 6.5 1.1e-27 97.1 6.5 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Kinesin PF00225.23 EGR28746.1 - 4.4e-92 308.5 5.9 7e-92 307.9 5.9 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR28746.1 - 3e-21 75.9 0.9 3e-21 75.9 0.9 2.7 3 0 0 3 3 3 1 Microtubule binding DUF87 PF01935.17 EGR28746.1 - 1.6 8.8 7.4 7.9 6.5 0.7 2.8 3 0 0 3 3 3 0 Helicase HerA, central domain Pkinase PF00069.25 EGR28747.1 - 5.7e-65 219.3 2.0 5.7e-65 219.3 2.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28747.1 - 3.4e-42 144.5 0.2 8.5e-42 143.2 0.2 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase MRP-S24 PF14955.6 EGR28747.1 - 0.0073 16.3 0.4 0.14 12.2 0.1 2.6 2 0 0 2 2 2 1 Mitochondrial ribosome subunit S24 RPN2_C PF18004.1 EGR28747.1 - 0.034 14.1 9.5 0.067 13.1 9.5 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Presenilin PF01080.17 EGR28747.1 - 0.56 8.9 5.9 0.85 8.3 5.9 1.3 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EGR28747.1 - 0.68 9.1 6.1 1 8.5 6.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter GTP_EFTU PF00009.27 EGR28748.1 - 1.6e-24 86.6 0.1 5.3e-24 84.8 0.1 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EGR28748.1 - 1.2e-16 60.7 0.2 1.2e-16 60.7 0.2 2.5 3 0 0 3 3 3 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EGR28748.1 - 1.1e-08 35.3 6.9 1.8e-06 28.2 0.1 3.1 3 0 0 3 3 3 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGR28748.1 - 2.9e-06 27.3 0.3 1.2e-05 25.4 0.0 2.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EGR28748.1 - 0.00022 21.1 0.3 0.00022 21.1 0.3 2.4 3 0 0 3 3 3 1 Elongation factor Tu domain 4 Roc PF08477.13 EGR28748.1 - 0.0036 17.5 0.0 0.013 15.7 0.0 2.0 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGR28748.1 - 0.02 14.3 0.0 0.071 12.5 0.0 2.0 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EGR28748.1 - 0.032 13.8 0.1 1.9 8.0 0.0 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B Intein_splicing PF14890.6 EGR28749.1 - 0.28 11.1 3.7 3.6 7.5 0.6 2.6 2 0 0 2 2 2 0 Intein splicing domain YtxH PF12732.7 EGR28749.1 - 1.5 9.4 4.4 4 8.0 0.1 3.0 3 1 0 3 3 3 0 YtxH-like protein PQ-loop PF04193.14 EGR28750.1 - 4.8e-28 96.7 24.5 3.6e-16 58.7 1.5 3.6 3 1 0 3 3 3 2 PQ loop repeat HMG_CoA_synt_N PF01154.17 EGR28751.1 - 1e-80 269.7 0.1 1.5e-80 269.2 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 EGR28751.1 - 1e-35 123.7 2.1 1.6e-35 123.1 2.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal DUF3307 PF11750.8 EGR28751.1 - 0.012 15.7 1.0 0.022 14.9 1.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3307) PI3Ka PF00613.20 EGR28751.1 - 0.015 14.7 2.8 0.14 11.5 2.8 2.1 1 1 0 1 1 1 0 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DEAD PF00270.29 EGR28753.1 - 2.8e-45 154.2 0.0 5.8e-45 153.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR28753.1 - 8e-30 103.4 0.0 8.5e-28 96.9 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.12 EGR28753.1 - 1.7e-23 82.7 0.0 1e-22 80.2 0.0 2.3 2 0 0 2 2 2 1 GUCT (NUC152) domain RRM_1 PF00076.22 EGR28753.1 - 3.2e-09 36.5 0.3 1.3e-08 34.5 0.3 2.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ResIII PF04851.15 EGR28753.1 - 2.1e-05 24.6 0.0 0.00015 21.9 0.0 2.2 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit RRM_7 PF16367.5 EGR28753.1 - 3.7e-05 23.8 0.0 0.00014 21.9 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif CMS1 PF14617.6 EGR28753.1 - 4.6e-05 22.9 0.0 0.00012 21.6 0.0 1.6 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 EGR28753.1 - 0.0022 17.3 0.0 0.0068 15.6 0.0 1.8 2 0 0 2 2 2 1 ERCC3/RAD25/XPB C-terminal helicase PAH PF02671.21 EGR28753.1 - 0.13 12.4 0.1 0.34 11.1 0.1 1.6 1 0 0 1 1 1 0 Paired amphipathic helix repeat Tctex-1 PF03645.13 EGR28754.1 - 3e-29 101.3 0.3 3.6e-29 101.0 0.3 1.1 1 0 0 1 1 1 1 Tctex-1 family CNOT1_TTP_bind PF16417.5 EGR28755.1 - 2.7e-56 189.8 7.2 2.7e-56 189.8 7.2 2.9 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_HEAT PF16418.5 EGR28755.1 - 5.1e-33 114.3 5.2 5.1e-33 114.3 5.2 3.1 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 HEAT repeat ASH PF15780.5 EGR28756.1 - 1.1e-57 192.3 50.1 0.0005 20.2 0.0 26.1 29 0 0 29 29 28 12 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 EGR28756.1 - 6.2e-23 80.9 1.0 2.4e-05 24.4 0.0 9.9 11 0 0 11 11 11 4 Flagellar-associated PapD-like Motile_Sperm PF00635.26 EGR28756.1 - 2.9e-16 59.3 68.1 0.012 15.5 0.0 17.3 17 0 0 17 17 17 8 MSP (Major sperm protein) domain Mago_nashi PF02792.14 EGR28756.1 - 1.9e-06 28.0 4.0 1.9e-06 28.0 4.0 5.0 4 0 0 4 4 3 1 Mago nashi protein DUF1573 PF07610.11 EGR28756.1 - 5.6e-06 26.3 61.1 0.021 14.9 0.1 19.3 21 3 0 21 21 20 2 Protein of unknown function (DUF1573) Hydin_ADK PF17213.3 EGR28756.1 - 0.001 19.4 0.1 0.001 19.4 0.1 6.0 5 1 1 6 6 5 2 Hydin Adenylate kinase-like domain TMEM131_like PF12371.8 EGR28756.1 - 0.0028 17.9 38.3 0.61 10.4 0.1 14.4 16 0 0 16 16 16 2 Transmembrane protein 131-like ADK PF00406.22 EGR28756.1 - 0.0058 16.7 0.7 0.48 10.5 0.4 2.9 2 0 0 2 2 2 1 Adenylate kinase Pro_CA PF00484.19 EGR28756.1 - 0.02 15.2 0.2 0.02 15.2 0.2 4.4 5 1 1 6 6 3 0 Carbonic anhydrase AAA_22 PF13401.6 EGR28756.1 - 0.076 13.3 0.0 0.32 11.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain Glyco_hydro_30C PF17189.4 EGR28756.1 - 0.089 13.0 3.3 58 4.0 0.1 5.1 4 0 0 4 4 4 0 Glycosyl hydrolase family 30 beta sandwich domain Ax_dynein_light PF10211.9 EGR28757.1 - 5.7e-79 264.4 11.3 7.1e-79 264.1 11.3 1.1 1 0 0 1 1 1 1 Axonemal dynein light chain GPHR_N PF12537.8 EGR28757.1 - 0.18 11.9 0.8 1.9 8.7 0.2 2.5 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal Actin PF00022.19 EGR28758.1 - 7.5e-138 459.5 0.0 9.8e-137 455.9 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGR28758.1 - 0.14 11.0 0.0 0.89 8.3 0.0 2.1 2 1 0 2 2 2 0 MreB/Mbl protein His_Phos_1 PF00300.22 EGR28759.1 - 1.2e-18 67.5 0.0 1.4e-18 67.3 0.0 1.0 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Pkinase PF00069.25 EGR28760.1 - 1.2e-44 152.7 0.6 1.4e-44 152.4 0.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28760.1 - 8e-25 87.6 0.0 8.9e-25 87.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28760.1 - 3.9e-10 39.5 0.1 4.9e-10 39.2 0.1 1.1 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGR28760.1 - 1.8e-06 27.2 0.4 1.8e-06 27.2 0.4 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGR28760.1 - 4.7e-05 22.3 0.0 6.6e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR28760.1 - 0.00013 22.0 0.0 0.00019 21.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR28760.1 - 0.00028 20.3 0.4 0.00039 19.9 0.4 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGR28760.1 - 0.0011 18.6 1.4 0.0017 18.0 1.4 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Seadorna_VP7 PF07387.11 EGR28760.1 - 0.0026 16.9 1.2 0.0036 16.4 1.2 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 SecM PF06558.12 EGR28761.1 - 0.27 11.3 0.1 0.27 11.3 0.1 3.0 2 1 1 3 3 3 0 Secretion monitor precursor protein (SecM) Beach PF02138.18 EGR28762.1 - 3.5e-103 344.8 8.0 4.6e-103 344.4 8.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 EGR28762.1 - 0.21 12.5 1.2 23 6.0 0.6 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat WXG100 PF06013.12 EGR28763.1 - 0.00057 20.1 3.2 0.00057 20.1 3.2 12.1 9 4 4 13 13 13 2 Proteins of 100 residues with WXG GBP PF02263.19 EGR28764.1 - 2.3e-36 125.4 0.0 2.9e-36 125.1 0.0 1.0 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain RHD3 PF05879.12 EGR28764.1 - 0.0021 16.3 0.0 0.0025 16.1 0.0 1.1 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) Mito_carr PF00153.27 EGR28765.1 - 3.9e-41 138.9 4.1 1.4e-19 69.8 0.2 2.8 3 0 0 3 3 3 2 Mitochondrial carrier protein zf-C3HC4_3 PF13920.6 EGR28765.1 - 2.8e-06 27.1 8.4 5.3e-06 26.2 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGR28765.1 - 1e-05 25.3 6.6 1e-05 25.3 6.6 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGR28765.1 - 3.9e-05 23.7 13.2 3.9e-05 23.7 13.2 2.2 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EGR28765.1 - 0.00067 19.5 14.8 0.00097 19.0 11.6 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGR28765.1 - 0.00086 19.3 11.1 0.00086 19.3 11.1 2.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGR28765.1 - 0.035 14.4 14.1 0.1 13.0 12.9 2.3 1 1 1 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 EGR28765.1 - 0.059 13.3 12.1 0.6 10.1 12.4 2.5 1 1 1 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 EGR28765.1 - 0.063 13.2 9.9 2.1 8.3 10.1 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 DUF3221 PF11518.8 EGR28765.1 - 0.54 10.7 3.5 0.26 11.7 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3221) DSPc PF00782.20 EGR28766.1 - 1.2e-11 44.6 0.0 1.2e-11 44.6 0.0 2.7 2 1 1 3 3 3 1 Dual specificity phosphatase, catalytic domain Presenilin PF01080.17 EGR28766.1 - 3 6.5 6.2 3.6 6.3 6.2 1.1 1 0 0 1 1 1 0 Presenilin YfhO PF09586.10 EGR28766.1 - 3.2 5.9 16.3 3.6 5.7 16.3 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO PGI PF00342.19 EGR28767.1 - 4e-152 507.2 0.0 4.7e-152 507.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DHC_N2 PF08393.13 EGR28768.1 - 6.5e-08 32.1 3.8 7.1e-08 32.0 3.8 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 DnaB PF00772.21 EGR28768.1 - 0.021 14.9 1.2 0.15 12.2 0.4 2.0 1 1 1 2 2 2 0 DnaB-like helicase N terminal domain PLU-1 PF08429.11 EGR28768.1 - 0.03 13.5 4.3 0.031 13.4 4.3 1.1 1 0 0 1 1 1 0 PLU-1-like protein PSDC PF12588.8 EGR28768.1 - 0.032 14.2 0.3 0.045 13.7 0.3 1.3 1 1 0 1 1 1 0 Phophatidylserine decarboxylase Bac_export_2 PF01312.19 EGR28769.1 - 0.17 11.0 4.9 0.24 10.6 4.9 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Beta-TrCP_D PF12125.8 EGR28770.1 - 0.015 15.2 1.5 0.054 13.4 0.1 2.6 3 0 0 3 3 3 0 D domain of beta-TrCP Pkinase PF00069.25 EGR28771.1 - 1.5e-66 224.5 0.1 3.9e-66 223.1 0.1 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28771.1 - 2.7e-46 157.9 0.0 5.4e-46 157.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EGR28771.1 - 3.5e-17 62.6 25.4 4.4e-09 36.7 5.3 4.3 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR28771.1 - 6.9e-17 59.7 18.1 0.00053 19.4 0.5 5.0 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGR28771.1 - 5.7e-16 57.0 18.3 0.00096 18.9 0.3 5.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGR28771.1 - 1.2e-08 34.6 17.6 0.00057 19.7 1.5 5.0 4 2 1 5 5 5 3 EF-hand domain pair RST PF12174.8 EGR28771.1 - 0.00035 20.4 2.2 0.73 9.8 0.1 3.0 2 0 0 2 2 2 2 RCD1-SRO-TAF4 (RST) plant domain p25-alpha PF05517.12 EGR28771.1 - 0.00038 20.6 15.9 0.0012 19.1 4.5 3.3 1 1 2 3 3 3 2 p25-alpha SPARC_Ca_bdg PF10591.9 EGR28771.1 - 0.00057 20.2 16.4 0.21 11.9 2.4 3.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 EGR28771.1 - 0.0013 18.2 16.6 0.07 12.6 0.3 4.9 4 0 0 4 4 4 2 EF hand ABC1 PF03109.16 EGR28771.1 - 0.0055 16.9 5.1 0.011 15.9 0.0 3.4 3 1 1 4 4 4 1 ABC1 family APH PF01636.23 EGR28771.1 - 0.095 12.6 0.0 0.22 11.4 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Histone_HNS PF00816.21 EGR28771.1 - 0.13 13.1 0.7 8.1 7.3 0.1 3.0 2 0 0 2 2 2 0 H-NS histone family Caleosin PF05042.13 EGR28771.1 - 0.15 12.0 15.0 2.1 8.3 0.2 4.6 3 2 1 5 5 5 0 Caleosin related protein EF-hand_4 PF12763.7 EGR28771.1 - 0.52 10.3 18.5 1.8 8.6 2.9 4.4 2 2 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 EGR28771.1 - 1.3 9.9 6.9 1.8 9.5 1.0 2.6 2 0 0 2 2 2 0 EF-hand domain EF-hand_10 PF14788.6 EGR28771.1 - 2.2 8.2 8.5 4 7.4 0.4 3.8 4 0 0 4 4 3 0 EF hand TF_AP-2 PF03299.14 EGR28771.1 - 2.7 7.9 5.3 3.1 7.7 2.6 2.5 2 1 0 2 2 2 0 Transcription factor AP-2 Pkinase PF00069.25 EGR28772.1 - 5.8e-69 232.4 0.2 8.8e-69 231.8 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28772.1 - 8e-38 130.2 0.1 1.5e-37 129.3 0.1 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28772.1 - 0.00019 20.9 0.0 0.0029 16.9 0.0 2.2 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EGR28772.1 - 0.0049 16.2 0.0 0.0076 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR28772.1 - 0.0082 15.0 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase CoaE PF01121.20 EGR28775.1 - 7e-13 48.6 0.0 8.2e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase FtsX PF02687.21 EGR28776.1 - 2e-15 57.0 22.1 4.9e-09 36.5 4.7 6.2 5 2 1 6 6 6 2 FtsX-like permease family ACPS PF01648.20 EGR28777.1 - 2.2e-15 56.7 0.2 2.6e-15 56.5 0.2 1.1 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily Clat_adaptor_s PF01217.20 EGR28778.1 - 3.4e-11 43.3 7.9 4.1e-11 43.0 7.9 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain zf-LITAF-like PF10601.9 EGR28779.1 - 1e-12 48.1 11.5 1.8e-12 47.4 11.5 1.3 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain GTP_EFTU PF00009.27 EGR28781.1 - 7.3e-56 188.8 1.2 7.3e-56 188.8 1.2 2.2 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGR28781.1 - 2.6e-19 69.6 0.0 8.6e-19 67.9 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGR28781.1 - 2.4e-14 53.5 2.0 2.4e-14 53.5 2.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGR28781.1 - 9e-05 22.5 0.1 0.00023 21.2 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ribosomal_S8 PF00410.19 EGR28781.1 - 0.062 13.2 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein S8 AAA_29 PF13555.6 EGR28781.1 - 0.087 12.6 0.3 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGR28781.1 - 0.11 12.4 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase PduV-EutP PF10662.9 EGR28781.1 - 1.2 8.9 5.7 6.7 6.5 2.6 2.8 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Enolase_C PF00113.22 EGR28782.1 - 4.9e-148 492.2 0.0 6.9e-148 491.7 0.0 1.2 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain MORN PF02493.20 EGR28782.1 - 4e-64 208.8 115.7 7.2e-07 28.7 5.7 15.0 15 0 0 15 15 15 14 MORN repeat Enolase_N PF03952.16 EGR28782.1 - 1e-56 190.7 0.0 1.8e-56 189.9 0.0 1.5 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EGR28782.1 - 2.1e-07 30.7 0.0 3.3e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EGR28782.1 - 8.7e-05 21.8 0.1 0.00015 21.0 0.1 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus eRF1_1 PF03463.15 EGR28783.1 - 1.5e-29 102.6 0.1 1.5e-29 102.6 0.1 1.7 2 0 0 2 2 2 1 eRF1 domain 1 eRF1_3 PF03465.15 EGR28783.1 - 9e-22 77.7 0.0 9e-22 77.7 0.0 2.2 3 0 0 3 3 3 1 eRF1 domain 3 eRF1_2 PF03464.15 EGR28783.1 - 1.8e-20 73.6 0.7 1.8e-20 73.6 0.7 2.0 2 0 0 2 2 2 1 eRF1 domain 2 DUF4609 PF15382.6 EGR28783.1 - 0.11 12.4 0.2 0.45 10.4 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4609) TFIIA_gamma_N PF02268.16 EGR28783.1 - 0.11 12.5 0.7 14 5.8 0.0 2.8 3 0 0 3 3 3 0 Transcription initiation factor IIA, gamma subunit, helical domain Bromo_TP_like PF17027.5 EGR28783.1 - 4.1 7.6 12.5 0.94 9.7 6.5 3.0 2 1 0 2 2 2 0 Histone-fold protein EF-hand_1 PF00036.32 EGR28784.1 - 5.8e-31 103.7 10.0 1.1e-07 30.9 2.8 4.6 4 0 0 4 4 4 4 EF hand Pkinase PF00069.25 EGR28784.1 - 5.9e-28 98.0 1.1 1.1e-27 97.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain EF-hand_7 PF13499.6 EGR28784.1 - 2.7e-27 95.0 6.8 2e-13 50.6 2.5 2.7 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR28784.1 - 9.5e-26 87.5 8.6 2.5e-07 30.1 0.1 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGR28784.1 - 1.8e-23 80.9 10.5 9e-06 25.0 0.0 4.7 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGR28784.1 - 3.8e-17 61.9 8.7 0.00019 21.2 0.9 4.6 2 1 2 4 4 4 4 EF-hand domain pair Pkinase_Tyr PF07714.17 EGR28784.1 - 4.4e-10 39.3 2.7 5e-09 35.8 2.7 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase EF-hand_4 PF12763.7 EGR28784.1 - 9.7e-07 28.7 4.7 0.018 15.0 0.1 2.8 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGR28784.1 - 2.7e-06 27.7 5.8 0.0068 16.7 0.3 3.0 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Sigma54_CBD PF04963.13 EGR28784.1 - 0.0012 18.7 4.6 0.0043 16.9 0.2 2.5 2 0 0 2 2 2 1 Sigma-54 factor, core binding domain EFhand_Ca_insen PF08726.10 EGR28784.1 - 0.0019 18.3 0.1 0.1 12.7 0.2 2.8 2 0 0 2 2 2 1 Ca2+ insensitive EF hand Prefoldin_3 PF13758.6 EGR28784.1 - 0.0097 15.9 7.3 1.1 9.4 0.0 3.9 3 1 1 4 4 4 1 Prefoldin subunit EF-hand_9 PF14658.6 EGR28784.1 - 0.1 12.9 0.4 2 8.8 0.1 2.7 2 1 0 2 2 2 0 EF-hand domain Pkinase PF00069.25 EGR28785.1 - 5.9e-44 150.4 0.1 6.9e-44 150.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28785.1 - 6e-17 61.8 0.0 7e-17 61.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28785.1 - 2.6e-06 27.0 0.0 3.5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR28785.1 - 0.00029 20.2 0.0 0.00045 19.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EGR28785.1 - 0.00096 18.3 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 EGR28785.1 - 0.0058 15.6 0.1 0.0086 15.1 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGR28785.1 - 0.01 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGR28785.1 - 0.15 10.8 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase WD40 PF00400.32 EGR28786.1 - 8.9e-42 140.3 13.7 8.1e-09 36.0 0.0 7.5 7 1 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR28786.1 - 2.9e-11 43.5 0.8 0.04 14.2 0.0 5.0 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGR28786.1 - 0.00025 20.5 0.0 0.039 13.3 0.0 2.9 2 1 0 3 3 3 1 WD40-like domain Nup160 PF11715.8 EGR28786.1 - 0.0012 17.6 4.5 0.12 10.9 0.1 3.9 1 1 3 5 5 5 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EGR28786.1 - 0.0067 15.0 0.0 0.44 9.0 0.0 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nbas_N PF15492.6 EGR28786.1 - 0.025 13.9 0.0 6.4 6.0 0.0 2.8 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal eIF2A PF08662.11 EGR28786.1 - 0.058 13.3 1.4 1.2 8.9 0.2 3.0 1 1 2 3 3 3 0 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 EGR28786.1 - 0.083 12.1 0.0 1.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Phage_TAC_2 PF06894.11 EGR28787.1 - 0.016 15.0 1.9 0.023 14.5 0.4 2.0 1 1 1 2 2 2 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G Cep57_MT_bd PF06657.13 EGR28788.1 - 0.0049 17.3 3.3 0.0049 17.3 3.3 2.7 2 1 1 3 3 3 1 Centrosome microtubule-binding domain of Cep57 TSC22 PF01166.18 EGR28788.1 - 0.021 15.1 0.3 0.021 15.1 0.3 3.6 2 1 1 3 3 3 0 TSC-22/dip/bun family Hist_deacetyl PF00850.19 EGR28789.1 - 1.5e-14 54.2 0.3 2.5e-14 53.5 0.1 1.5 2 0 0 2 2 2 1 Histone deacetylase domain PYNP_C PF07831.13 EGR28789.1 - 0.064 12.9 0.0 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain Hist_deacetyl PF00850.19 EGR28790.1 - 1.1e-39 136.8 0.1 1.3e-39 136.5 0.1 1.0 1 0 0 1 1 1 1 Histone deacetylase domain PRMT5_C PF17286.2 EGR28790.1 - 0.034 14.0 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 PRMT5 oligomerisation domain ChAPs PF09295.10 EGR28791.1 - 0.049 12.6 0.4 0.053 12.5 0.4 1.0 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) DUF4598 PF15370.6 EGR28791.1 - 0.083 13.4 0.8 0.22 12.0 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4598) cNMP_binding PF00027.29 EGR28792.1 - 1.1e-05 25.4 0.0 0.031 14.3 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF5453 PF17534.2 EGR28792.1 - 0.052 13.5 0.5 0.052 13.5 0.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5453) FHA PF00498.26 EGR28793.1 - 4.2e-10 39.8 0.3 1.6e-09 37.9 0.3 2.2 1 1 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGR28793.1 - 6.7e-09 36.0 0.2 1.8e-08 34.6 0.1 1.7 1 1 1 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain MU2_FHA PF18221.1 EGR28793.1 - 0.0024 17.9 0.1 0.012 15.7 0.0 1.9 1 1 1 2 2 2 1 Mutator 2 Fork head associated domain Nuf2 PF03800.14 EGR28793.1 - 0.0035 17.5 3.9 0.0035 17.5 3.9 2.2 1 1 1 2 2 2 1 Nuf2 family FERM_f0 PF16511.5 EGR28793.1 - 0.011 16.1 5.4 0.011 16.1 5.4 2.5 1 1 1 3 3 3 0 N-terminal or F0 domain of Talin-head FERM Pro_isomerase PF00160.21 EGR28794.1 - 3e-27 95.8 0.2 3.3e-27 95.7 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HgmA PF04209.13 EGR28795.1 - 1.4e-200 666.4 2.5 1.6e-200 666.2 2.5 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase 2Fe-2S_thioredx PF01257.19 EGR28796.1 - 2.3e-54 183.2 1.5 3.2e-54 182.7 1.5 1.2 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Dynamin_M PF01031.20 EGR28796.1 - 0.007 15.6 0.1 0.011 15.0 0.1 1.3 1 0 0 1 1 1 1 Dynamin central region LOB PF03195.14 EGR28796.1 - 0.034 14.7 0.1 2.5 8.7 0.0 2.5 2 0 0 2 2 2 0 Lateral organ boundaries (LOB) domain DUF1636 PF07845.11 EGR28796.1 - 0.11 12.9 1.0 0.3 11.5 0.2 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1636) SPC25 PF06703.11 EGR28797.1 - 0.0045 16.8 0.4 0.0045 16.8 0.4 2.4 2 1 0 2 2 2 1 Microsomal signal peptidase 25 kDa subunit (SPC25) TPR_MLP1_2 PF07926.12 EGR28797.1 - 1 9.4 22.5 0.019 15.1 15.3 1.8 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein PRKG1_interact PF15898.5 EGR28797.1 - 5.6 7.9 21.4 0.28 12.1 11.3 2.9 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain PGM_PMM_I PF02878.16 EGR28798.1 - 8.5e-33 113.0 0.0 1.5e-32 112.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EGR28798.1 - 5.6e-27 94.2 0.0 9.3e-27 93.5 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EGR28798.1 - 4.7e-14 52.9 0.0 1.4e-13 51.3 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EGR28798.1 - 5e-08 33.0 0.0 1.3e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain Kinesin PF00225.23 EGR28800.1 - 2.7e-82 276.4 5.6 1.5e-73 247.6 3.7 3.5 3 0 0 3 3 3 2 Kinesin motor domain Microtub_bd PF16796.5 EGR28800.1 - 3.9e-17 62.6 0.8 3.9e-17 62.6 0.8 5.5 5 1 0 5 5 5 1 Microtubule binding Cys_Met_Meta_PP PF01053.20 EGR28801.1 - 1.8e-115 385.6 0.0 2e-115 385.4 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Met_gamma_lyase PF06838.11 EGR28801.1 - 3.5e-08 32.4 0.0 4.3e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 Methionine gamma-lyase Aminotran_1_2 PF00155.21 EGR28801.1 - 2.7e-06 26.8 0.1 4.1e-06 26.2 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGR28801.1 - 0.029 13.3 0.1 0.063 12.2 0.1 1.6 2 0 0 2 2 2 0 Aminotransferase class-V LOH1CR12 PF10158.9 EGR28801.1 - 0.057 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Tumour suppressor protein RCC1_2 PF13540.6 EGR28802.1 - 3.4e-27 93.6 11.1 5.2e-09 35.7 0.1 6.1 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EGR28802.1 - 6.2e-20 71.6 24.1 9.6e-07 29.3 0.6 7.3 6 3 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat DUF3942 PF13078.6 EGR28802.1 - 0.016 15.5 2.6 0.066 13.5 0.1 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF3942) M60-like_N PF17291.2 EGR28803.1 - 0.016 15.1 0.0 0.15 11.9 0.0 2.7 3 0 0 3 3 3 0 N-terminal domain of M60-like peptidases DSPc PF00782.20 EGR28804.1 - 4.6e-15 55.6 1.0 7.9e-15 54.8 1.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CBM_20 PF00686.19 EGR28804.1 - 6.5e-11 42.0 0.1 1.5e-10 40.8 0.1 1.6 1 0 0 1 1 1 1 Starch binding domain CDKN3 PF05706.12 EGR28804.1 - 0.00047 19.9 0.1 0.00094 18.9 0.1 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 EGR28804.1 - 0.11 12.5 0.0 0.34 10.8 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family IBN_N PF03810.19 EGR28805.1 - 6.6e-08 32.4 1.3 6.6e-08 32.4 1.3 3.9 4 0 0 4 4 4 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 EGR28805.1 - 0.0023 18.5 0.5 0.03 14.9 0.2 3.2 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region NABP PF07990.12 EGR28806.1 - 0.2 11.2 3.1 0.19 11.2 3.1 1.1 1 0 0 1 1 1 0 Nucleic acid binding protein NABP Kazal_1 PF00050.21 EGR28807.1 - 0.21 11.6 17.1 0.64 10.1 2.7 3.4 2 2 0 2 2 2 0 Kazal-type serine protease inhibitor domain ADH_zinc_N_2 PF13602.6 EGR28808.1 - 7.8e-15 56.1 0.0 1.5e-14 55.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGR28808.1 - 2.6e-07 30.7 0.0 5.1e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGR28808.1 - 0.0032 17.3 0.0 0.006 16.5 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Rotamase_2 PF13145.6 EGR28808.1 - 0.051 14.4 0.1 1.1 10.1 0.0 2.4 2 0 0 2 2 2 0 PPIC-type PPIASE domain DEAD PF00270.29 EGR28809.1 - 2.5e-41 141.4 0.5 1.2e-40 139.1 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR28809.1 - 1.1e-31 109.4 0.8 1.1e-31 109.4 0.8 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGR28809.1 - 5.3e-06 26.5 0.7 1.3e-05 25.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGR28809.1 - 0.0038 17.5 0.1 0.021 15.1 0.1 2.4 1 1 0 1 1 1 1 AAA domain RRM_1 PF00076.22 EGR28811.1 - 1.2e-42 143.6 0.3 1.6e-22 79.1 0.2 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGR28811.1 - 3.4e-07 30.3 0.2 0.004 17.2 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 EGR28811.1 - 1.5e-06 27.8 0.1 0.0049 16.5 0.1 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PHM7_cyt PF14703.6 EGR28811.1 - 0.0036 17.6 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 2 Cytosolic domain of 10TM putative phosphate transporter OB_RNB PF08206.11 EGR28811.1 - 0.0038 16.9 0.2 2.4 7.9 0.0 2.5 2 0 0 2 2 2 2 Ribonuclease B OB domain Limkain-b1 PF11608.8 EGR28811.1 - 0.017 15.2 0.1 4.8 7.3 0.0 2.5 2 0 0 2 2 2 0 Limkain b1 RRM_3 PF08777.11 EGR28811.1 - 0.024 14.7 0.7 4.9 7.2 0.1 2.4 2 1 0 2 2 2 0 RNA binding motif Cas_Cas2CT1978 PF09707.10 EGR28811.1 - 0.052 13.6 0.0 11 6.1 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cas2CT1978) Suppressor_APC PF11414.8 EGR28812.1 - 0.034 14.2 2.6 0.067 13.3 2.6 1.6 1 1 0 1 1 1 0 Adenomatous polyposis coli tumour suppressor protein STOP PF05217.12 EGR28812.1 - 0.11 12.8 0.1 0.11 12.8 0.1 3.6 4 0 0 4 4 4 0 STOP protein MORN PF02493.20 EGR28813.1 - 5.3e-49 161.3 84.8 1.1e-06 28.2 3.9 10.9 11 0 0 11 11 11 10 MORN repeat SMN PF06003.12 EGR28814.1 - 1e-07 31.5 0.3 1e-07 31.5 0.3 3.3 2 1 2 4 4 4 2 Survival motor neuron protein (SMN) TUDOR PF00567.24 EGR28814.1 - 0.00012 22.0 3.8 0.082 12.9 0.0 3.4 1 1 1 2 2 2 2 Tudor domain Tudor_2 PF18104.1 EGR28814.1 - 0.0016 18.1 0.2 0.0095 15.6 0.1 2.2 2 0 0 2 2 2 1 Jumonji domain-containing protein 2A Tudor domain Agenet PF05641.12 EGR28814.1 - 0.0017 18.8 0.2 0.11 12.9 0.1 2.8 2 0 0 2 2 2 1 Agenet domain DUF4537 PF15057.6 EGR28814.1 - 0.036 14.1 0.1 0.036 14.1 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4537) LRR_9 PF14580.6 EGR28815.1 - 0.0021 17.6 0.0 0.0043 16.6 0.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeat DDHD PF02862.17 EGR28815.1 - 0.031 14.4 1.5 0.034 14.3 1.5 1.2 1 0 0 1 1 1 0 DDHD domain CDC45 PF02724.14 EGR28815.1 - 0.039 12.3 4.6 0.037 12.3 4.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3464 PF11947.8 EGR28815.1 - 0.14 11.9 2.4 0.24 11.2 2.4 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CobT PF06213.12 EGR28815.1 - 0.54 9.6 8.6 0.8 9.0 8.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DNA_pol_phi PF04931.13 EGR28815.1 - 0.59 8.2 11.8 0.83 7.7 11.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi Menin PF05053.13 EGR28815.1 - 0.65 8.3 5.6 0.86 7.9 5.6 1.1 1 0 0 1 1 1 0 Menin Connexin PF00029.19 EGR28815.1 - 0.86 9.3 4.5 1.2 8.8 4.5 1.2 1 0 0 1 1 1 0 Connexin YqfQ PF14181.6 EGR28815.1 - 2.3 8.4 10.1 4.9 7.3 10.1 1.5 1 0 0 1 1 1 0 YqfQ-like protein V_ATPase_I PF01496.19 EGR28815.1 - 3.7 5.3 5.7 4 5.2 5.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 EGR28815.1 - 3.7 6.2 5.5 4 6.1 5.5 1.1 1 0 0 1 1 1 0 Presenilin CH PF00307.31 EGR28816.1 - 3.4e-12 46.5 50.0 3.1e-05 24.1 0.4 7.0 6 1 1 7 7 7 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGR28816.1 - 6.6 6.6 15.4 0.84 9.5 0.3 5.1 5 1 0 5 5 5 0 CAMSAP CH domain HisKA PF00512.25 EGR28817.1 - 0.074 13.1 0.7 0.37 10.9 0.1 2.5 2 0 0 2 2 2 0 His Kinase A (phospho-acceptor) domain Pkinase PF00069.25 EGR28818.1 - 1e-35 123.4 0.1 1.2e-35 123.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28818.1 - 4.1e-22 78.7 0.0 5.3e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR28818.1 - 1.7e-06 27.1 0.0 2.3e-06 26.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGR28818.1 - 4.3e-06 25.9 0.1 5.5e-06 25.6 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGR28818.1 - 9.7e-05 21.8 0.0 0.00019 20.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGR28818.1 - 0.0079 16.1 0.0 0.011 15.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGR28818.1 - 0.014 15.0 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DNA_pol_A PF00476.20 EGR28819.1 - 3.8e-40 138.1 0.3 7.6e-40 137.1 0.1 1.5 2 0 0 2 2 2 1 DNA polymerase family A Semialdhyde_dhC PF02774.18 EGR28819.1 - 0.056 13.5 0.0 0.088 12.9 0.0 1.4 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain HU-CCDC81_bac_2 PF18175.1 EGR28819.1 - 0.09 12.7 0.6 0.19 11.7 0.0 1.8 2 0 0 2 2 2 0 CCDC81-like prokaryotic HU domain 2 DNA_pol_A_exo1 PF01612.20 EGR28820.1 - 1.2e-09 38.1 1.5 1.8e-09 37.5 1.3 1.5 1 1 0 1 1 1 1 3'-5' exonuclease Rogdi_lz PF10259.9 EGR28820.1 - 0.026 14.0 0.4 0.034 13.6 0.4 1.1 1 0 0 1 1 1 0 Rogdi leucine zipper containing protein zf-LITAF-like PF10601.9 EGR28821.1 - 5.6e-09 36.1 1.1 7.8e-09 35.7 0.3 1.7 2 0 0 2 2 2 1 LITAF-like zinc ribbon domain DZR PF12773.7 EGR28821.1 - 0.023 14.7 0.2 0.057 13.4 0.1 1.6 2 0 0 2 2 2 0 Double zinc ribbon Lar_restr_allev PF14354.6 EGR28821.1 - 0.096 13.1 0.0 0.24 11.8 0.0 1.8 1 0 0 1 1 1 0 Restriction alleviation protein Lar Ntox35 PF15534.6 EGR28821.1 - 0.14 12.6 3.5 0.34 11.4 3.5 1.6 1 0 0 1 1 1 0 Bacterial toxin 35 zinc_ribbon_9 PF14369.6 EGR28821.1 - 1.1 9.6 3.2 7.9 6.8 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon zinc_ribbon_15 PF17032.5 EGR28821.1 - 1.4 9.7 6.3 14 6.5 0.2 3.1 3 0 0 3 3 3 0 zinc-ribbon family DUF1510 PF07423.11 EGR28822.1 - 0.22 11.7 3.0 0.42 10.8 0.8 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1510) CLZ PF16526.5 EGR28822.1 - 3 8.3 19.5 8.4 6.8 0.1 6.3 5 2 2 7 7 7 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Myb_DNA-binding PF00249.31 EGR28823.1 - 3.5e-19 68.7 16.9 9.4e-08 32.1 0.9 5.2 5 1 0 5 5 5 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGR28823.1 - 8.1e-15 54.8 24.6 5.1e-08 33.0 1.7 5.5 4 1 1 5 5 5 3 Myb-like DNA-binding domain RGS_DHEX PF18148.1 EGR28823.1 - 0.05 13.7 0.8 0.05 13.7 0.8 4.2 3 2 1 4 4 4 0 Regulator of G-protein signalling DHEX domain DUF2322 PF10084.9 EGR28823.1 - 0.087 12.9 0.4 0.24 11.4 0.1 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2322) DUF3127 PF11325.8 EGR28823.1 - 0.61 10.4 10.0 1.4 9.2 0.2 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3127) SANT_DAMP1_like PF16282.5 EGR28823.1 - 2.3 8.5 6.9 2.1 8.6 0.1 3.5 3 1 0 3 3 3 0 SANT/Myb-like domain of DAMP1 WD40 PF00400.32 EGR28824.1 - 2.7e-23 81.8 12.0 0.00021 22.0 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR28824.1 - 3.2e-05 24.1 0.2 0.075 13.3 0.0 3.7 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 EGR28824.1 - 0.00076 18.6 0.2 0.043 12.9 0.0 2.8 2 1 1 3 3 3 1 VID27 C-terminal WD40-like domain Helicase_C PF00271.31 EGR28825.1 - 3e-16 59.7 0.0 1.4e-15 57.6 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HA2 PF04408.23 EGR28825.1 - 1.4e-13 51.1 0.1 1.4e-13 51.1 0.1 2.6 2 1 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 EGR28825.1 - 0.00072 19.4 0.3 0.0026 17.6 0.3 2.0 1 1 0 1 1 1 1 DEAD/DEAH box helicase tRNA-synt_2b PF00587.25 EGR28827.1 - 2e-32 112.6 2.3 3.2e-32 112.0 0.0 2.3 3 1 0 3 3 3 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGR28827.1 - 3.5e-12 46.3 0.2 7.6e-12 45.2 0.2 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EGR28827.1 - 5.1e-12 45.7 0.0 1.3e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EGR28827.1 - 0.032 14.3 0.0 0.077 13.1 0.0 1.7 1 0 0 1 1 1 0 TGS domain AMP-binding PF00501.28 EGR28828.1 - 1.7e-85 287.2 0.0 2.3e-85 286.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGR28828.1 - 3.9e-05 24.6 0.0 8.8e-05 23.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain MOZ_SAS PF01853.18 EGR28828.1 - 0.013 15.2 0.9 0.33 10.6 0.2 2.5 2 0 0 2 2 2 0 MOZ/SAS family VIR_N PF15912.5 EGR28828.1 - 0.019 14.6 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Virilizer, N-terminal DUF3781 PF12636.7 EGR28828.1 - 0.092 12.6 4.3 1.1 9.1 0.4 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) MORN PF02493.20 EGR28829.1 - 2.6e-76 247.2 94.9 3.4e-06 26.6 0.0 14.7 14 0 0 14 14 14 14 MORN repeat DUF2671 PF10877.8 EGR28829.1 - 0.018 14.8 1.5 1.4 8.7 0.2 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF2671) Merozoite_SPAM PF07133.11 EGR28831.1 - 0.18 11.8 33.6 0.19 11.7 33.6 1.0 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.14 EGR28831.1 - 2.6 6.2 17.1 2.7 6.2 17.1 1.0 1 0 0 1 1 1 0 CDC45-like protein CSG2 PF16965.5 EGR28831.1 - 9.2 5.1 6.3 10 4.9 6.3 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator LSM PF01423.22 EGR28832.1 - 7.5e-14 51.2 0.1 8.7e-14 51.0 0.1 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGR28832.1 - 1.2e-06 28.6 0.0 1.2e-06 28.5 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.7 EGR28832.1 - 0.092 12.9 0.0 0.099 12.8 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain FtsJ PF01728.19 EGR28833.1 - 3.4e-07 30.5 1.5 5.3e-07 29.9 0.1 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase DRE2_N PF16803.5 EGR28833.1 - 0.019 15.2 2.9 0.019 15.2 2.9 2.5 2 1 1 3 3 3 0 Fe-S cluster assembly protein DRE2 N-terminus LAS2 PF15792.5 EGR28833.1 - 0.3 11.7 5.2 0.94 10.1 0.3 3.4 3 0 0 3 3 3 0 Lung adenoma susceptibility protein 2 FHIPEP PF00771.20 EGR28833.1 - 1.8 7.0 7.8 0.14 10.6 0.4 2.2 2 1 0 2 2 2 0 FHIPEP family RNA_polI_A14 PF08203.11 EGR28833.1 - 5 7.9 9.3 9.5 7.0 1.6 3.6 3 0 0 3 3 3 0 Yeast RNA polymerase I subunit RPA14 ATP_bind_1 PF03029.17 EGR28834.1 - 1.7e-61 208.1 0.7 2e-61 207.8 0.7 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 EGR28834.1 - 9.5e-05 22.0 0.8 0.00044 19.8 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EGR28834.1 - 0.00015 21.8 0.0 0.0019 18.2 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGR28834.1 - 0.00016 21.7 0.0 0.56 10.1 0.0 3.0 3 0 0 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 EGR28834.1 - 0.0015 18.1 0.0 0.016 14.8 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 EGR28834.1 - 0.0019 18.4 0.0 0.0032 17.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain G-alpha PF00503.20 EGR28834.1 - 0.0025 17.0 0.3 0.009 15.2 0.0 1.9 2 0 0 2 2 2 1 G-protein alpha subunit NACHT PF05729.12 EGR28834.1 - 0.0033 17.4 0.0 0.0047 16.9 0.0 1.4 1 0 0 1 1 1 1 NACHT domain CLP1_P PF16575.5 EGR28834.1 - 0.0034 17.2 0.0 0.69 9.7 0.0 2.2 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop cobW PF02492.19 EGR28834.1 - 0.0036 16.9 0.3 1 8.9 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain RNA_helicase PF00910.22 EGR28834.1 - 0.0078 16.6 0.4 0.33 11.3 0.0 2.3 2 1 0 2 2 2 1 RNA helicase AAA_16 PF13191.6 EGR28834.1 - 0.0079 16.6 0.0 0.0086 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AIG1 PF04548.16 EGR28834.1 - 0.012 15.0 0.4 0.02 14.2 0.1 1.5 2 0 0 2 2 2 0 AIG1 family FtsK_SpoIIIE PF01580.18 EGR28834.1 - 0.013 14.8 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family MeaB PF03308.16 EGR28834.1 - 0.015 14.3 0.0 0.059 12.3 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 EGR28834.1 - 0.015 15.6 0.0 0.024 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ras PF00071.22 EGR28834.1 - 0.018 14.6 0.5 0.74 9.4 0.1 2.2 2 0 0 2 2 2 0 Ras family SRP54 PF00448.22 EGR28834.1 - 0.019 14.6 0.0 0.074 12.7 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 EGR28834.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGR28834.1 - 0.026 14.5 0.0 0.063 13.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 EGR28834.1 - 0.026 14.3 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EGR28834.1 - 0.026 14.2 0.0 0.028 14.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain Arf PF00025.21 EGR28834.1 - 0.027 13.9 0.1 0.4 10.1 0.0 2.2 2 0 0 2 2 2 0 ADP-ribosylation factor family NTPase_1 PF03266.15 EGR28834.1 - 0.028 14.4 0.1 0.48 10.3 0.1 2.1 2 0 0 2 2 2 0 NTPase Roc PF08477.13 EGR28834.1 - 0.028 14.6 0.0 0.77 10.0 0.0 2.4 2 1 1 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase NB-ARC PF00931.22 EGR28834.1 - 0.03 13.5 0.0 0.068 12.4 0.0 1.5 2 0 0 2 2 2 0 NB-ARC domain DUF87 PF01935.17 EGR28834.1 - 0.032 14.3 0.0 0.062 13.4 0.0 1.5 1 1 0 1 1 1 0 Helicase HerA, central domain PduV-EutP PF10662.9 EGR28834.1 - 0.041 13.6 0.5 0.37 10.5 0.1 2.2 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 EGR28834.1 - 0.056 14.0 0.0 0.1 13.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGR28834.1 - 0.058 13.7 0.0 0.079 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EGR28834.1 - 0.063 13.7 0.1 0.11 12.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 EGR28834.1 - 0.096 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Septin PF00735.18 EGR28834.1 - 0.096 11.9 0.0 0.13 11.5 0.0 1.5 1 1 0 1 1 1 0 Septin Dynamin_M PF01031.20 EGR28835.1 - 9.1e-84 281.0 3.5 9.1e-84 281.0 3.5 2.0 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 EGR28835.1 - 2.6e-49 167.5 0.1 2.6e-49 167.5 0.1 2.5 3 1 0 3 3 3 1 Dynamin family GED PF02212.18 EGR28835.1 - 4.4e-21 74.8 2.9 1.7e-20 73.0 2.9 2.1 1 0 0 1 1 1 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGR28835.1 - 5.6e-05 23.2 0.3 0.00033 20.7 0.3 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_21 PF13304.6 EGR28835.1 - 0.011 15.6 0.3 0.3 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system FeoB_N PF02421.18 EGR28835.1 - 0.029 13.9 0.7 8.8 5.8 0.4 2.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Taeniidae_ag PF05596.11 EGR28835.1 - 0.03 14.3 1.7 0.11 12.5 0.6 2.6 2 0 0 2 2 2 0 Taeniidae antigen NPV_P10 PF05531.12 EGR28835.1 - 0.44 11.0 9.3 0.83 10.2 0.2 4.7 4 1 1 5 5 5 0 Nucleopolyhedrovirus P10 protein Cas6_N PF17952.1 EGR28835.1 - 0.75 10.1 5.3 0.75 10.1 0.2 3.0 3 0 0 3 3 3 0 Cas6 N-terminal domain ABC_tran PF00005.27 EGR28835.1 - 1.7 9.2 0.0 1.7 9.2 0.0 3.0 3 2 0 3 3 3 0 ABC transporter RRM_1 PF00076.22 EGR28836.1 - 0.00014 21.6 0.6 0.017 15.0 0.0 3.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BHD_3 PF10405.9 EGR28836.1 - 0.11 12.9 0.5 0.5 10.8 0.1 2.3 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 3 JAB PF01398.21 EGR28837.1 - 3.5e-29 101.2 0.1 5.8e-29 100.5 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EGR28837.1 - 6.5e-08 32.4 0.0 1e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 EGR28837.1 - 0.0044 17.1 1.1 0.013 15.5 0.0 2.0 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) SCO1-SenC PF02630.14 EGR28838.1 - 4.7e-06 26.6 10.7 17 5.3 0.0 7.3 7 0 0 7 7 7 1 SCO1/SenC SoxE PF06525.11 EGR28838.1 - 0.0051 16.3 17.0 12 5.3 0.0 7.4 7 1 1 8 8 8 3 Sulfocyanin (SoxE) domain DUF3687 PF12459.8 EGR28838.1 - 0.019 14.5 33.3 0.5 9.9 0.3 7.7 7 0 0 7 7 7 0 D-Ala-teichoic acid biosynthesis protein DCR PF14047.6 EGR28838.1 - 0.043 14.0 0.3 2.3e+02 2.1 0.0 5.3 7 0 0 7 7 7 0 Dppa2/4 conserved region DUF4224 PF13986.6 EGR28838.1 - 0.14 12.1 0.0 35 4.4 0.0 3.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4224) Sigma70_r4_2 PF08281.12 EGR28838.1 - 0.54 10.0 1.4 1.3e+02 2.4 0.0 4.3 6 0 0 6 6 6 0 Sigma-70, region 4 Ion_trans_2 PF07885.16 EGR28840.1 - 2.1e-11 43.6 8.8 2.1e-11 43.6 8.8 2.7 2 0 0 2 2 2 1 Ion channel SK_channel PF03530.14 EGR28840.1 - 1.6e-05 24.9 2.6 1.6e-05 24.9 2.6 3.0 3 1 0 3 3 3 1 Calcium-activated SK potassium channel RabGAP-TBC PF00566.18 EGR28841.1 - 6.5e-05 22.7 0.5 7.4e-05 22.5 0.5 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Pkinase PF00069.25 EGR28842.1 - 7.1e-73 245.2 0.3 9.9e-73 244.7 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28842.1 - 1.3e-30 106.5 0.1 4e-30 105.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EGR28842.1 - 0.052 13.5 0.0 7.9 6.3 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 EGR28842.1 - 0.28 10.8 5.9 1.1 8.9 0.1 2.6 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Baculo_LEF-11 PF06385.12 EGR28842.1 - 0.36 11.3 4.4 18 5.9 1.1 2.8 3 0 0 3 3 3 0 Baculovirus LEF-11 protein Ras PF00071.22 EGR28843.1 - 3.3e-41 140.6 0.5 4.2e-41 140.2 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR28843.1 - 5.6e-25 87.9 1.6 5.6e-25 87.9 0.1 1.7 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR28843.1 - 5e-13 48.9 0.8 7.3e-13 48.3 0.8 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR28843.1 - 6.7e-09 35.8 0.1 1.4e-08 34.8 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGR28843.1 - 0.00076 19.1 0.1 0.0015 18.1 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain PRP38 PF03371.15 EGR28843.1 - 0.0048 16.8 1.4 0.01 15.7 1.4 1.5 1 0 0 1 1 1 1 PRP38 family DUF4309 PF14172.6 EGR28843.1 - 0.014 15.4 0.5 0.022 14.8 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4309) RsgA_GTPase PF03193.16 EGR28843.1 - 0.061 13.2 3.2 0.14 12.1 0.4 2.2 1 1 1 2 2 2 0 RsgA GTPase PUL PF08324.11 EGR28845.1 - 7.9e-38 130.3 0.3 1.1e-37 129.8 0.3 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 EGR28845.1 - 1.2e-30 106.1 2.0 3.8e-30 104.4 2.0 1.9 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 EGR28845.1 - 4.5e-28 96.9 7.6 4.8e-05 24.1 0.2 7.6 7 0 0 7 7 7 6 WD domain, G-beta repeat P5-ATPase PF12409.8 EGR28845.1 - 0.41 10.8 4.0 1 9.5 4.0 1.6 1 0 0 1 1 1 0 P5-type ATPase cation transporter V_ATPase_I PF01496.19 EGR28846.1 - 6.7e-28 97.1 10.3 7.8e-28 96.9 10.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family V_ATPase_I PF01496.19 EGR28847.1 - 4.8e-152 507.7 17.3 5.5e-152 507.5 17.3 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family ISK_Channel PF02060.15 EGR28847.1 - 0.14 11.9 1.0 0.82 9.4 0.1 2.6 2 0 0 2 2 2 0 Slow voltage-gated potassium channel Glu_cyclase_2 PF05096.12 EGR28848.1 - 0.026 13.9 0.1 0.027 13.9 0.1 1.1 1 0 0 1 1 1 0 Glutamine cyclotransferase RHH_1 PF01402.21 EGR28848.1 - 0.12 12.3 0.1 1.1 9.4 0.0 2.2 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family HHA PF05321.11 EGR28848.1 - 0.13 12.6 0.3 1.4 9.3 0.0 2.3 1 1 1 2 2 2 0 Haemolysin expression modulating protein DUF641 PF04859.12 EGR28849.1 - 0.0098 16.2 2.4 0.0098 16.2 2.4 2.0 1 1 1 2 2 2 1 Plant protein of unknown function (DUF641) V_ATPase_I PF01496.19 EGR28849.1 - 0.083 10.8 8.6 0.098 10.6 8.6 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PIEZO PF15917.5 EGR28849.1 - 0.17 11.3 12.5 0.24 10.9 12.5 1.2 1 0 0 1 1 1 0 Piezo Exonuc_VII_L PF02601.15 EGR28849.1 - 0.2 11.2 7.6 0.23 11.0 7.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1664 PF07889.12 EGR28849.1 - 0.23 11.5 4.8 0.45 10.6 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF1043 PF06295.12 EGR28849.1 - 0.23 11.4 13.8 0.49 10.4 13.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DHR10 PF18595.1 EGR28849.1 - 0.43 10.7 13.0 0.052 13.6 8.0 2.0 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain SOGA PF11365.8 EGR28849.1 - 0.44 11.7 9.4 0.7 11.1 8.4 2.0 1 1 1 2 2 2 0 Protein SOGA DUF948 PF06103.11 EGR28849.1 - 0.71 10.2 3.6 0.7 10.2 0.8 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Cluap1 PF10234.9 EGR28849.1 - 0.75 9.1 17.5 0.45 9.9 15.8 1.5 1 1 0 1 1 1 0 Clusterin-associated protein-1 APG6_N PF17675.1 EGR28849.1 - 1.4 9.4 21.7 11 6.6 16.0 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 EGR28849.1 - 1.5 9.1 14.9 1.4 9.1 10.1 2.2 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF349 PF03993.12 EGR28849.1 - 1.7 9.0 7.5 2.8 8.3 5.6 2.4 1 1 1 2 2 2 0 Domain of Unknown Function (DUF349) DUF4407 PF14362.6 EGR28849.1 - 2.5 7.4 9.6 3.3 7.0 9.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3450 PF11932.8 EGR28849.1 - 3.2 7.0 15.5 0.24 10.7 8.2 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3450) DUF2802 PF10975.8 EGR28849.1 - 4.6 7.4 9.1 52 4.1 7.4 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2802) DUF2937 PF11157.8 EGR28849.1 - 4.9 6.8 6.0 9.4 5.9 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) cNMP_binding PF00027.29 EGR28852.1 - 4.1e-43 145.4 0.2 1.4e-17 63.6 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase PF00069.25 EGR28852.1 - 5.9e-13 48.8 0.1 1.7e-12 47.3 0.1 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28852.1 - 0.0021 17.4 0.0 0.0062 15.8 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 EGR28852.1 - 0.097 12.3 4.1 0.066 12.8 2.1 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 IBR PF01485.21 EGR28853.1 - 9.8e-17 60.9 27.8 1e-12 48.1 11.7 4.0 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EGR28853.1 - 0.0099 15.7 13.2 0.0099 15.7 13.2 4.4 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGR28853.1 - 0.015 15.6 10.1 0.015 15.6 10.1 4.2 3 1 2 5 5 5 0 Ring finger domain DUF898 PF05987.13 EGR28853.1 - 0.067 12.2 1.5 0.1 11.6 1.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Pex24p PF06398.11 EGR28853.1 - 0.21 10.5 2.8 0.4 9.6 2.8 1.5 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin EI24 PF07264.11 EGR28853.1 - 0.32 11.2 8.7 0.89 9.8 8.7 1.6 1 1 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) DUF5345 PF17280.2 EGR28853.1 - 1.3 9.1 4.6 4.2 7.4 0.1 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5345) WD40 PF00400.32 EGR28856.1 - 6.1e-07 30.0 0.1 1.6 9.7 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat WD40 PF00400.32 EGR28857.1 - 1.3e-07 32.1 1.0 0.083 13.8 0.0 5.0 6 0 0 6 6 6 2 WD domain, G-beta repeat ETRAMP PF09716.10 EGR28857.1 - 0.54 10.4 0.0 0.54 10.4 0.0 4.0 3 2 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Dynein_light PF01221.18 EGR28858.1 - 5.3e-32 110.0 0.8 5.9e-32 109.8 0.8 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 HJURP_C PF12347.8 EGR28858.1 - 0.12 12.4 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat Ribosomal_S26e PF01283.19 EGR28859.1 - 2.6e-45 153.3 8.7 3.2e-45 153.0 8.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Sgf11 PF08209.11 EGR28859.1 - 0.0037 16.8 0.2 0.0076 15.8 0.2 1.5 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) SRP19 PF01922.17 EGR28859.1 - 0.007 17.3 0.2 0.01 16.7 0.1 1.5 1 1 0 1 1 1 1 SRP19 protein ADD_ATRX PF17981.1 EGR28859.1 - 0.012 15.4 0.6 0.012 15.4 0.6 1.8 2 0 0 2 2 2 0 Cysteine Rich ADD domain EF-hand_7 PF13499.6 EGR28860.1 - 8.4e-10 39.0 6.8 1.9e-07 31.5 1.0 4.0 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 EGR28860.1 - 1.1e-09 37.2 7.7 0.015 14.8 0.3 4.9 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGR28860.1 - 2.5e-09 36.3 8.3 0.045 13.7 0.1 5.0 5 0 0 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 EGR28860.1 - 5.9e-07 29.2 0.1 1.3e-05 24.9 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 EGR28860.1 - 0.006 16.0 2.9 0.15 11.6 0.0 3.0 2 0 0 2 2 2 1 EF hand Caleosin PF05042.13 EGR28860.1 - 0.054 13.4 10.3 1 9.2 0.2 4.7 2 1 2 5 5 5 0 Caleosin related protein Syntaxin-6_N PF09177.11 EGR28860.1 - 0.31 11.6 5.4 0.76 10.4 0.5 2.9 3 0 0 3 3 3 0 Syntaxin 6, N-terminal DUF2400 PF09674.10 EGR28860.1 - 0.94 9.4 9.7 4 7.4 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2400) Phage_X PF05155.15 EGR28860.1 - 5.1 7.6 8.4 0.66 10.4 0.3 3.1 2 1 1 3 3 3 0 Phage X family ETRAMP PF09716.10 EGR28861.1 - 5 7.3 5.9 4.6 7.4 1.4 2.9 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF4179 PF13786.6 EGR28861.1 - 7.3 7.1 6.3 18 5.9 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) Phage_holin_7_1 PF16081.5 EGR28862.1 - 0.12 12.5 12.1 0.13 12.5 9.9 2.0 1 1 1 2 2 2 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family Senescence PF06911.12 EGR28862.1 - 0.42 10.9 15.3 5.2 7.3 13.8 2.6 2 1 0 2 2 2 0 Senescence-associated protein ABC_tran PF00005.27 EGR28863.1 - 4.2e-53 179.5 0.9 1e-30 107.0 0.0 3.1 3 0 0 3 3 3 2 ABC transporter ABC_membrane PF00664.23 EGR28863.1 - 3.7e-31 108.8 51.1 1.1e-19 71.1 27.0 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EGR28863.1 - 1.4e-09 37.7 11.7 6.8e-06 25.7 2.1 4.5 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGR28863.1 - 1e-07 32.0 0.1 0.0087 16.0 0.2 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 EGR28863.1 - 1.7e-06 28.1 0.4 0.06 13.1 0.1 4.2 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGR28863.1 - 2.3e-06 27.3 0.2 0.11 12.3 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGR28863.1 - 7.2e-05 22.9 0.3 0.084 13.0 0.0 3.2 3 0 0 3 3 3 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EGR28863.1 - 0.0011 19.4 0.0 1.9 8.9 0.0 2.7 2 0 0 2 2 2 2 AAA ATPase domain Roc PF08477.13 EGR28863.1 - 0.027 14.7 0.5 5.3 7.3 0.0 4.1 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 EGR28863.1 - 0.034 14.4 0.8 26 5.1 0.0 3.5 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGR28863.1 - 0.064 13.8 25.7 0.12 12.9 0.0 4.9 5 0 0 5 5 4 0 AAA domain Dynamin_N PF00350.23 EGR28863.1 - 0.32 11.1 4.7 8.7 6.4 0.0 3.2 3 0 0 3 3 3 0 Dynamin family NB-ARC PF00931.22 EGR28863.1 - 0.77 8.9 8.5 6.1 5.9 0.0 3.6 3 1 0 3 3 3 0 NB-ARC domain MORN PF02493.20 EGR28864.1 - 3.3e-41 136.8 73.9 3.7e-08 32.8 3.8 10.7 11 0 0 11 11 11 9 MORN repeat GTP_EFTU PF00009.27 EGR28864.1 - 8.6e-39 133.1 0.0 4.7e-38 130.7 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGR28864.1 - 1.1e-20 73.9 0.2 1.1e-20 73.9 0.2 3.5 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGR28864.1 - 1.3e-05 25.5 0.0 7.9e-05 23.0 0.0 2.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGR28864.1 - 1.9e-05 24.7 0.3 0.00029 20.9 0.0 3.3 3 1 0 3 3 3 1 50S ribosome-binding GTPase DHquinase_II PF01220.19 EGR28864.1 - 0.43 10.2 2.3 0.42 10.3 0.1 2.1 2 0 0 2 2 2 0 Dehydroquinase class II Ras PF00071.22 EGR28865.1 - 3.2e-40 137.4 0.0 3.8e-40 137.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR28865.1 - 7e-24 84.3 0.0 8.9e-24 84.0 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR28865.1 - 7.8e-10 38.5 0.0 9.6e-10 38.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family AAA_24 PF13479.6 EGR28865.1 - 0.078 12.7 0.1 3.5 7.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 EGR28865.1 - 0.094 12.2 0.1 0.16 11.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region 5_nucleotid_C PF02872.18 EGR28866.1 - 3.5e-38 131.3 0.0 6.4e-38 130.4 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EGR28866.1 - 1.9e-10 41.6 0.2 5.2e-10 40.2 0.1 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Sugar_tr PF00083.24 EGR28867.1 - 1e-34 120.2 14.3 1.1e-34 120.1 14.3 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter B12D PF06522.11 EGR28867.1 - 0.083 12.7 0.1 0.25 11.2 0.1 1.8 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit DUF454 PF04304.13 EGR28867.1 - 0.14 12.2 5.6 0.053 13.5 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF454) Bax1-I PF01027.20 EGR28867.1 - 0.15 11.9 16.6 0.099 12.5 14.5 1.8 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF2070 PF09843.9 EGR28867.1 - 0.76 8.0 10.2 1.1 7.5 10.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3792 PF12670.7 EGR28867.1 - 6.3 7.0 17.8 1.1 9.4 13.1 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF3792) Piezo_RRas_bdg PF12166.8 EGR28868.1 - 1.2e-61 209.3 0.9 5.1e-51 174.3 0.1 2.1 1 1 1 2 2 2 2 Piezo non-specific cation channel, R-Ras-binding domain DUF3365 PF11845.8 EGR28869.1 - 6.9 7.0 6.5 2.3 8.5 0.2 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF3365) HMG_box PF00505.19 EGR28870.1 - 3.6e-14 52.9 2.3 4.5e-14 52.6 2.3 1.2 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGR28870.1 - 1.8e-06 28.4 0.9 2.3e-06 28.1 0.9 1.2 1 0 0 1 1 1 1 HMG-box domain MFS_1 PF07690.16 EGR28871.1 - 9.4e-37 126.7 15.0 1.5e-25 89.9 1.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGR28871.1 - 1.1e-21 77.2 32.6 1.9e-21 76.5 32.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Asp PF00026.23 EGR28872.1 - 0.0022 17.5 0.1 0.0026 17.2 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TFIIB PF00382.19 EGR28874.1 - 4.8e-08 32.9 0.5 6.4e-08 32.5 0.5 1.2 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Bax1-I PF01027.20 EGR28875.1 - 3.6e-31 108.6 25.2 4.6e-31 108.3 25.2 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Vac7 PF12751.7 EGR28875.1 - 0.0017 17.9 1.2 0.0025 17.3 1.2 1.3 1 0 0 1 1 1 1 Vacuolar segregation subunit 7 DUF4203 PF13886.6 EGR28875.1 - 0.02 14.6 15.3 0.03 14.0 15.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) BaxI_1 PF12811.7 EGR28875.1 - 1.3 8.5 17.8 2.6 7.5 17.9 1.4 1 1 0 1 1 1 0 Bax inhibitor 1 like DUF4220 PF13968.6 EGR28875.1 - 1.8 7.9 7.5 2.6 7.3 7.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4220) MBOAT PF03062.19 EGR28876.1 - 8e-17 61.6 22.2 8e-17 61.6 22.2 2.1 1 1 1 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Med14 PF08638.11 EGR28876.1 - 0.065 12.6 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Mediator complex subunit MED14 MBOAT_2 PF13813.6 EGR28876.1 - 0.62 10.4 6.4 0.093 13.0 1.7 2.1 2 0 0 2 2 2 0 Membrane bound O-acyl transferase family BBL5 PF07289.11 EGR28877.1 - 5.5e-55 186.7 5.1 1.5e-47 162.2 2.0 2.0 1 1 1 2 2 2 2 Bardet-Biedl syndrome 5 protein GRAM PF02893.20 EGR28877.1 - 0.034 14.0 0.0 0.081 12.8 0.0 1.7 1 0 0 1 1 1 0 GRAM domain PH_TFIIH PF08567.11 EGR28877.1 - 0.055 13.8 0.0 0.11 12.8 0.0 1.5 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Lipase_3 PF01764.25 EGR28878.1 - 3.4e-27 95.0 0.0 4.1e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 EGR28878.1 - 9.5e-05 22.2 0.1 0.00012 21.9 0.1 1.2 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 EGR28878.1 - 0.00015 21.2 0.0 0.00016 21.1 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGR28878.1 - 0.0029 18.2 0.0 0.0031 18.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGR28878.1 - 0.0043 16.7 0.0 0.0063 16.2 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2974 PF11187.8 EGR28878.1 - 0.0071 15.9 0.3 0.041 13.4 0.3 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 EGR28878.1 - 0.011 15.6 0.0 0.013 15.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF915 PF06028.11 EGR28878.1 - 0.012 15.0 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) DUF900 PF05990.12 EGR28878.1 - 0.046 13.2 0.0 0.06 12.8 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Thioesterase PF00975.20 EGR28878.1 - 0.067 13.3 0.0 0.089 12.9 0.0 1.1 1 0 0 1 1 1 0 Thioesterase domain PAF-AH_p_II PF03403.13 EGR28878.1 - 0.09 11.3 0.0 0.11 10.9 0.0 1.2 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Kinesin PF00225.23 EGR28879.1 - 1.1e-95 320.4 5.8 1.1e-95 320.4 5.8 1.9 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGR28879.1 - 5.2e-26 91.4 2.7 5.2e-26 91.4 2.7 3.4 3 1 0 3 3 3 1 Microtubule binding ZapB PF06005.12 EGR28879.1 - 0.024 15.1 4.8 0.024 15.1 4.8 4.3 4 0 0 4 4 4 0 Cell division protein ZapB Pesticin PF16754.5 EGR28879.1 - 0.94 9.4 7.4 7.9 6.4 0.0 3.2 2 1 1 3 3 3 0 Bacterial toxin homologue of phage lysozyme, C-term TSC22 PF01166.18 EGR28879.1 - 2.1 8.7 15.9 1 9.7 2.0 3.8 3 0 0 3 3 3 0 TSC-22/dip/bun family Serinc PF03348.15 EGR28880.1 - 2.2e-90 303.7 35.3 2.5e-90 303.5 35.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) OAD_gamma PF04277.13 EGR28880.1 - 0.0082 16.7 0.0 0.14 12.8 0.0 2.8 2 0 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain DivIC PF04977.15 EGR28880.1 - 0.016 14.9 10.0 0.019 14.7 8.1 2.1 2 0 0 2 2 2 0 Septum formation initiator ETRAMP PF09716.10 EGR28880.1 - 0.075 13.1 0.1 2.2 8.4 1.0 2.9 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) YnfE PF17452.2 EGR28880.1 - 0.19 12.0 2.9 0.44 10.9 2.9 1.5 1 0 0 1 1 1 0 Uncharacterized YnfE-like Wzy_C PF04932.15 EGR28880.1 - 7.9 6.1 15.4 4.1e+02 0.5 14.3 3.1 1 1 0 1 1 1 0 O-Antigen ligase HNH PF01844.23 EGR28883.1 - 8e-06 25.9 0.3 1.3e-05 25.2 0.3 1.4 1 0 0 1 1 1 1 HNH endonuclease HNH_5 PF14279.6 EGR28883.1 - 7.6e-05 22.5 0.3 0.00012 21.8 0.3 1.5 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 EGR28883.1 - 0.0002 21.2 0.0 0.00032 20.6 0.0 1.3 1 0 0 1 1 1 1 HNH endonuclease RCC1 PF00415.18 EGR28884.1 - 2.3e-58 194.6 9.7 1.7e-16 60.6 0.1 5.1 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR28884.1 - 6.2e-25 86.4 21.9 1.2e-09 37.7 0.2 5.2 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Kelch_2 PF07646.15 EGR28884.1 - 0.11 12.5 0.4 15 5.7 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Kinesin PF00225.23 EGR28887.1 - 3.3e-109 364.8 0.5 8.1e-109 363.6 0.4 1.6 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR28887.1 - 5.5e-20 71.8 0.0 1.4e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding Kinesin_assoc PF16183.5 EGR28887.1 - 0.00064 19.9 0.0 0.0016 18.6 0.0 1.6 1 0 0 1 1 1 1 Kinesin-associated DUF1192 PF06698.11 EGR28887.1 - 0.11 12.5 0.1 0.53 10.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Tup_N PF08581.10 EGR28887.1 - 0.21 11.9 0.3 0.21 11.9 0.3 2.1 3 0 0 3 3 3 0 Tup N-terminal Dioxygenase_N PF04444.14 EGR28888.1 - 0.087 12.7 0.1 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 Catechol dioxygenase N terminus V-ATPase_G PF03179.15 EGR28889.1 - 1.4e-24 86.6 10.7 1.7e-24 86.4 10.7 1.1 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 EGR28889.1 - 1.4e-06 27.9 10.4 1.7e-06 27.6 10.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3552) ATP-synt_B PF00430.18 EGR28889.1 - 0.002 18.2 8.2 0.002 18.2 8.2 1.6 2 0 0 2 2 2 1 ATP synthase B/B' CF(0) PB1 PF00564.24 EGR28889.1 - 0.019 14.9 0.3 0.028 14.4 0.3 1.2 1 0 0 1 1 1 0 PB1 domain DinB PF05163.12 EGR28889.1 - 0.05 13.5 2.7 0.06 13.3 2.5 1.3 1 1 0 1 1 1 0 DinB family Peptidase_C50 PF03568.17 EGR28889.1 - 0.067 12.3 3.0 0.072 12.2 3.0 1.0 1 0 0 1 1 1 0 Peptidase family C50 DUF4407 PF14362.6 EGR28889.1 - 0.074 12.4 3.8 0.082 12.3 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V-ATPase_G_2 PF16999.5 EGR28889.1 - 0.083 13.3 11.6 1.1 9.7 9.0 2.1 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit DUF883 PF05957.13 EGR28889.1 - 0.17 12.5 3.8 0.21 12.2 3.3 1.5 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) KfrA_N PF11740.8 EGR28889.1 - 0.24 12.1 5.5 0.39 11.4 5.5 1.3 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Prominin PF05478.11 EGR28889.1 - 0.35 8.8 5.9 0.37 8.7 5.9 1.0 1 0 0 1 1 1 0 Prominin vATP-synt_E PF01991.18 EGR28889.1 - 3.2 7.1 16.4 1.2 8.5 11.6 2.0 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit ATP-synt_E_2 PF08112.11 EGR28889.1 - 6.4 7.1 12.4 4.9 7.5 1.1 3.5 2 2 1 3 3 3 0 ATP synthase epsilon subunit ANAPC4_WD40 PF12894.7 EGR28890.1 - 1.9e-06 28.0 0.0 0.0066 16.7 0.0 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGR28890.1 - 3.8e-05 24.4 0.0 0.55 11.2 0.1 3.0 2 1 0 2 2 2 2 WD domain, G-beta repeat ASF1_hist_chap PF04729.13 EGR28891.1 - 5.4e-62 208.3 0.3 7.8e-62 207.8 0.3 1.2 1 0 0 1 1 1 1 ASF1 like histone chaperone Pkinase PF00069.25 EGR28894.1 - 1.5e-54 185.2 3.2 1.5e-54 185.2 3.2 2.4 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28894.1 - 1.8e-38 132.3 0.5 1.8e-38 132.3 0.5 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase AGTRAP PF06396.11 EGR28895.1 - 0.045 13.6 0.4 0.11 12.3 0.4 1.7 1 1 0 1 1 1 0 Angiotensin II, type I receptor-associated protein (AGTRAP) AOX PF01786.17 EGR28896.1 - 2.7e-86 288.6 0.2 3.2e-86 288.4 0.2 1.0 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 EGR28896.1 - 0.22 11.3 2.2 0.24 11.1 0.2 2.0 2 1 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 AOX PF01786.17 EGR28897.1 - 9.4e-56 188.8 0.4 1.4e-55 188.2 0.4 1.2 1 0 0 1 1 1 1 Alternative oxidase MORN PF02493.20 EGR28897.1 - 2.2e-44 146.7 71.6 5.6e-07 29.1 4.0 10.3 10 0 0 10 10 10 9 MORN repeat ER_lumen_recept PF00810.18 EGR28899.1 - 3.9e-45 154.3 12.8 6.4e-45 153.6 12.8 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor Cluap1 PF10234.9 EGR28900.1 - 2.1e-97 325.7 17.0 3.5e-97 325.0 17.0 1.4 1 0 0 1 1 1 1 Clusterin-associated protein-1 IFP_35_N PF07334.13 EGR28900.1 - 0.12 12.4 7.2 0.28 11.3 5.8 2.5 1 1 1 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Prominin PF05478.11 EGR28900.1 - 2.1 6.2 12.9 0.94 7.3 10.7 1.6 1 1 0 1 1 1 0 Prominin NOT2_3_5 PF04153.18 EGR28901.1 - 1.4e-08 34.9 2.7 2.4e-08 34.1 2.7 1.4 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Arginase PF00491.21 EGR28902.1 - 6.1e-25 88.3 0.0 9.7e-25 87.6 0.0 1.3 1 1 0 1 1 1 1 Arginase family DUF2816 PF10992.8 EGR28903.1 - 3.2e-25 87.8 24.1 3.2e-25 87.8 24.1 3.6 3 1 0 3 3 3 2 Protein of unknown function (DUF2816) Aldedh PF00171.22 EGR28904.1 - 7.5e-138 459.9 0.1 8.5e-138 459.7 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGR28904.1 - 0.00012 21.3 0.1 0.00065 18.8 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA reductase (LuxC) EF-hand_1 PF00036.32 EGR28906.1 - 3.5e-31 104.4 23.8 1.7e-06 27.2 0.1 8.0 7 0 0 7 7 7 6 EF hand EF-hand_6 PF13405.6 EGR28906.1 - 6.4e-31 103.6 20.1 8.7e-05 22.2 0.1 8.0 8 0 0 8 8 8 6 EF-hand domain EF-hand_7 PF13499.6 EGR28906.1 - 2.9e-28 98.1 23.9 9.8e-09 35.5 3.7 5.6 3 1 2 5 5 5 5 EF-hand domain pair EF-hand_8 PF13833.6 EGR28906.1 - 3.2e-21 74.9 13.3 6.6e-08 32.3 0.2 6.9 6 1 1 7 7 7 4 EF-hand domain pair EF-hand_5 PF13202.6 EGR28906.1 - 2.3e-18 64.8 16.5 0.00051 19.4 0.1 7.1 6 0 0 6 6 6 4 EF hand EF-hand_4 PF12763.7 EGR28906.1 - 0.00021 21.2 5.8 0.072 13.0 0.8 3.6 2 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 EGR28906.1 - 0.0024 18.7 6.3 0.58 11.0 0.3 4.0 3 1 0 3 3 3 2 EF-hand domain PilN_bio_d PF18222.1 EGR28906.1 - 0.11 12.9 1.7 2.3 8.6 0.0 3.5 3 1 1 4 4 4 0 PilN biogenesis protein dimerization domain EF-hand_10 PF14788.6 EGR28906.1 - 0.62 10.0 7.6 5.8 6.9 0.5 4.3 3 1 1 4 4 4 0 EF hand RVP_2 PF08284.11 EGR28907.1 - 0.082 12.7 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Retroviral aspartyl protease PP2C_C PF07830.13 EGR28908.1 - 0.72 10.4 5.3 0.1 13.0 1.1 1.8 1 1 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain Kinesin PF00225.23 EGR28909.1 - 5.5e-123 410.1 0.5 5.5e-123 410.1 0.5 2.8 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGR28909.1 - 8.9e-27 93.9 0.0 8.9e-27 93.9 0.0 3.0 2 1 0 2 2 2 1 Microtubule binding AAA_22 PF13401.6 EGR28909.1 - 0.64 10.3 0.0 0.64 10.3 0.0 3.0 3 1 1 4 4 4 0 AAA domain Ribosomal_L11_N PF03946.14 EGR28910.1 - 2e-17 62.8 1.0 3.7e-17 61.9 0.2 1.8 2 0 0 2 2 2 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EGR28910.1 - 2e-15 57.0 1.2 3.3e-15 56.3 1.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain Ribosomal_L1 PF00687.21 EGR28911.1 - 1.8e-41 142.1 5.6 2.3e-41 141.8 5.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family MORN PF02493.20 EGR28912.1 - 1.4e-58 191.4 86.1 7.5e-09 35.0 1.3 10.0 10 0 0 10 10 10 9 MORN repeat Tudor_2 PF18104.1 EGR28912.1 - 0.00021 20.9 25.3 0.3 10.8 4.1 6.5 6 0 0 6 6 6 5 Jumonji domain-containing protein 2A Tudor domain DSHCT PF08148.12 EGR28913.1 - 3.6e-32 111.3 0.0 9.4e-32 109.9 0.0 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 EGR28913.1 - 1.1e-16 61.1 0.2 3e-16 59.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR28913.1 - 1.1e-07 32.1 3.9 5.7e-07 29.9 0.9 3.2 3 1 1 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGR28913.1 - 1e-05 25.6 0.0 1e-05 25.6 0.0 2.4 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit ATPase_2 PF01637.18 EGR28913.1 - 0.0016 18.4 0.1 0.0016 18.4 0.1 2.5 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_22 PF13401.6 EGR28913.1 - 0.024 14.9 0.0 0.15 12.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain vATP-synt_E PF01991.18 EGR28914.1 - 1.5e-38 132.2 17.3 7.9e-38 129.9 17.3 1.8 1 1 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF1667 PF07892.11 EGR28914.1 - 0.33 11.0 2.8 5.2 7.2 0.6 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1667) DUF3306 PF11748.8 EGR28914.1 - 0.73 10.7 3.9 1.2 10.1 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) DUF2201 PF09967.9 EGR28914.1 - 1.7 8.8 3.8 3.3 7.9 0.4 2.4 2 1 0 2 2 2 0 VWA-like domain (DUF2201) Pkinase PF00069.25 EGR28915.1 - 5.5e-60 203.0 1.2 7.6e-60 202.5 1.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28915.1 - 2.8e-39 134.9 0.1 4.4e-39 134.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28915.1 - 0.00078 18.8 0.3 0.017 14.4 0.0 2.4 2 2 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR28915.1 - 0.0011 17.8 0.0 0.0028 16.5 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR28915.1 - 0.011 15.7 0.1 0.23 11.3 0.1 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Peptidase_S10 PF00450.22 EGR28916.1 - 6.3e-67 226.8 15.0 5.6e-35 121.6 1.4 2.3 1 1 1 2 2 2 2 Serine carboxypeptidase Tctex-1 PF03645.13 EGR28917.1 - 0.025 14.8 0.2 0.037 14.3 0.2 1.4 1 0 0 1 1 1 0 Tctex-1 family START PF01852.19 EGR28919.1 - 2.2e-23 82.7 0.1 3.4e-23 82.1 0.1 1.3 1 0 0 1 1 1 1 START domain TauE PF01925.19 EGR28919.1 - 0.017 14.8 0.5 0.025 14.2 0.5 1.1 1 0 0 1 1 1 0 Sulfite exporter TauE/SafE DUF456 PF04306.13 EGR28919.1 - 0.085 13.1 1.2 0.15 12.4 1.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) DUF3074 PF11274.8 EGR28919.1 - 0.16 11.9 0.1 0.16 11.9 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3074) Gly-zipper_Omp PF13488.6 EGR28919.1 - 6.4 6.9 8.1 19 5.4 8.3 1.7 1 1 1 2 2 2 0 Glycine zipper MORN PF02493.20 EGR28920.1 - 1.5e-21 74.9 38.2 2.4e-07 30.3 2.6 6.8 7 0 0 7 7 7 6 MORN repeat Pkinase PF00069.25 EGR28921.1 - 2.9e-44 151.4 1.4 6.3e-44 150.3 1.4 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28921.1 - 1.4e-29 103.1 0.2 2.9e-29 102.2 0.2 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase ANTH PF07651.16 EGR28921.1 - 3.9e-08 32.6 0.4 1.7e-07 30.5 0.1 2.2 2 0 0 2 2 2 1 ANTH domain Kinase-like PF14531.6 EGR28921.1 - 3.3e-05 23.4 0.0 6.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR28921.1 - 0.0008 18.8 0.0 0.0014 18.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EGR28921.1 - 0.019 14.5 1.9 0.034 13.7 0.3 2.2 2 1 0 2 2 2 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 EGR28921.1 - 0.041 12.7 0.1 0.064 12.0 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase UPF0767 PF15990.5 EGR28922.1 - 0.085 13.0 0.2 0.19 11.9 0.2 1.5 1 0 0 1 1 1 0 UPF0767 family C2 PF00168.30 EGR28922.1 - 0.16 12.3 1.7 0.87 9.9 1.4 2.3 1 1 1 2 2 2 0 C2 domain RNase_T PF00929.24 EGR28923.1 - 4.3e-31 108.7 0.1 4.8e-31 108.5 0.1 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 EGR28923.1 - 3.6e-08 33.6 0.2 4.5e-08 33.3 0.2 1.1 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like Ras PF00071.22 EGR28924.1 - 2.4e-62 209.3 0.6 3.1e-62 208.9 0.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR28924.1 - 7.2e-33 113.4 0.1 7.2e-33 113.4 0.1 2.0 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR28924.1 - 5.9e-14 51.9 0.0 8.3e-14 51.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR28924.1 - 6.2e-06 26.3 0.0 1.5e-05 25.1 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGR28924.1 - 6.6e-06 25.6 0.2 8.4e-06 25.3 0.2 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGR28924.1 - 9.3e-06 25.3 0.0 7.5e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGR28924.1 - 4.7e-05 23.4 0.2 0.2 11.6 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EGR28924.1 - 0.0056 17.0 0.1 0.064 13.5 0.1 2.2 1 1 0 1 1 1 1 AAA domain HEPN_AbiU2 PF18734.1 EGR28924.1 - 0.0075 15.8 0.3 0.011 15.3 0.3 1.3 1 0 0 1 1 1 1 AbiU2 ATP_bind_1 PF03029.17 EGR28924.1 - 0.0098 15.7 0.2 0.099 12.4 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 EGR28924.1 - 0.01 15.3 0.0 0.02 14.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EGR28924.1 - 0.019 14.7 1.1 0.36 10.5 0.1 2.1 1 1 0 2 2 2 0 AAA domain ATPase_2 PF01637.18 EGR28924.1 - 0.024 14.6 0.7 0.042 13.8 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF3067 PF11267.8 EGR28924.1 - 0.045 14.3 0.0 0.1 13.2 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3067) DNA_pol_E_B PF04042.16 EGR28924.1 - 0.082 12.2 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B ResIII PF04851.15 EGR28924.1 - 0.12 12.4 3.7 0.74 9.8 3.7 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit TetR_C_16 PF17920.1 EGR28924.1 - 0.24 11.7 0.0 0.39 11.0 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain ABC_tran PF00005.27 EGR28924.1 - 7.3 7.1 6.7 17 5.9 6.7 1.8 1 1 0 1 1 1 0 ABC transporter LMBR1 PF04791.16 EGR28925.1 - 5.9e-80 269.6 53.8 7.6e-80 269.3 53.8 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF5336 PF17270.2 EGR28925.1 - 0.13 11.9 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5336) NIF PF03031.18 EGR28926.1 - 1.1e-40 139.0 7.2 8.1e-27 93.9 3.1 2.3 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Mito_carr PF00153.27 EGR28927.1 - 1.6e-57 191.4 2.7 1.2e-18 66.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Botulinum_HA-17 PF05588.11 EGR28927.1 - 4 7.5 10.2 0.065 13.3 0.8 2.5 3 0 0 3 3 3 0 Clostridium botulinum HA-17 domain MT-A70 PF05063.14 EGR28928.1 - 2.9e-12 46.8 0.4 3.6e-12 46.6 0.4 1.1 1 0 0 1 1 1 1 MT-A70 DUF2229 PF09989.9 EGR28929.1 - 0.098 12.3 2.6 0.13 11.9 1.9 1.6 1 1 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) SF-assemblin PF06705.11 EGR28929.1 - 0.2 10.9 31.6 0.14 11.5 22.3 2.6 1 1 1 2 2 2 0 SF-assemblin/beta giardin DUF745 PF05335.13 EGR28929.1 - 3.6 7.3 8.7 0.47 10.2 3.7 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF745) WD40 PF00400.32 EGR28930.1 - 4.4e-15 55.8 4.1 0.46 11.4 0.0 9.0 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR28930.1 - 4.3e-08 33.3 0.1 0.0012 19.1 0.0 3.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3866 PF12982.7 EGR28930.1 - 0.015 14.5 0.0 0.027 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3866) EF-hand_7 PF13499.6 EGR28930.1 - 0.03 14.8 0.1 0.14 12.6 0.1 2.2 1 0 0 1 1 1 0 EF-hand domain pair BBS2_Mid PF14783.6 EGR28930.1 - 0.05 13.7 1.8 1.6 8.8 0.3 3.8 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region DUF1796 PF08795.10 EGR28930.1 - 0.099 12.6 9.9 2.4 8.1 8.6 3.1 2 1 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) Prefoldin PF02996.17 EGR28931.1 - 2.4e-26 92.0 3.9 3.1e-26 91.6 3.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit Sec20 PF03908.13 EGR28931.1 - 0.015 15.2 2.4 0.071 13.0 0.1 2.1 2 0 0 2 2 2 0 Sec20 DUF3990 PF13151.6 EGR28931.1 - 0.016 14.9 1.2 0.017 14.8 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3990) DUF745 PF05335.13 EGR28931.1 - 0.41 10.4 7.0 0.11 12.2 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) DUF1664 PF07889.12 EGR28931.1 - 0.53 10.3 4.3 0.46 10.5 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) LMBR1 PF04791.16 EGR28931.1 - 1 8.2 4.6 1.2 7.9 4.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Vps36_ESCRT-II PF11605.8 EGR28932.1 - 0.63 10.3 7.2 0.86 9.8 7.2 1.2 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 TMEM154 PF15102.6 EGR28933.1 - 4.7e-05 23.3 6.4 4.7e-05 23.3 6.4 2.3 3 0 0 3 3 3 1 TMEM154 protein family Orf78 PF06024.12 EGR28933.1 - 7.1e-05 23.0 7.5 7.1e-05 23.0 7.5 4.3 3 1 1 4 4 4 1 Orf78 (ac78) Shisa PF13908.6 EGR28933.1 - 0.00018 21.8 1.9 0.00056 20.2 1.9 1.8 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator DUF4064 PF13273.6 EGR28933.1 - 0.00046 20.4 1.7 0.0029 17.9 1.7 2.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) TraG_N PF07916.11 EGR28933.1 - 0.00077 18.4 0.1 0.0053 15.7 0.0 2.0 2 0 0 2 2 2 1 TraG-like protein, N-terminal region LRRC37AB_C PF14914.6 EGR28933.1 - 0.0079 16.1 13.1 0.0079 16.1 13.1 4.1 4 0 0 4 4 4 1 LRRC37A/B like protein 1 C-terminal domain DUF3377 PF11857.8 EGR28933.1 - 0.035 14.0 3.7 0.11 12.4 3.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) m04gp34like PF12216.8 EGR28933.1 - 0.042 13.4 0.2 0.12 12.0 0.2 1.7 1 0 0 1 1 1 0 Immune evasion protein FAM60A PF15396.6 EGR28933.1 - 0.066 13.2 0.1 0.066 13.2 0.1 4.5 4 1 0 4 4 3 0 Protein Family FAM60A 7tm_1 PF00001.21 EGR28933.1 - 0.089 12.1 0.6 0.17 11.2 0.6 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Ctr PF04145.15 EGR28933.1 - 0.16 12.6 4.3 12 6.5 0.6 3.3 3 1 0 3 3 3 0 Ctr copper transporter family T2SSF PF00482.23 EGR28933.1 - 0.17 11.8 0.6 0.67 9.9 0.2 2.2 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F FANC_SAP PF18081.1 EGR28933.1 - 0.24 11.6 0.2 0.5 10.6 0.2 1.5 1 0 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain Wzy_C PF04932.15 EGR28933.1 - 0.47 10.1 3.5 1.1 8.8 3.5 1.6 1 0 0 1 1 1 0 O-Antigen ligase GWT1 PF06423.12 EGR28933.1 - 0.53 10.4 9.4 0.12 12.4 4.2 2.6 2 0 0 2 2 2 0 GWT1 ParcG PF10274.9 EGR28934.1 - 5.9e-81 271.0 0.1 8.4e-81 270.5 0.1 1.2 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 EGR28934.1 - 0.0013 18.4 0.0 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 Dimerisation and cyclophilin-binding domain of Mon2 Ion_trans_2 PF07885.16 EGR28935.1 - 3.5e-06 26.9 2.1 3.5e-06 26.9 2.1 2.8 2 0 0 2 2 2 1 Ion channel DUF4878 PF12870.7 EGR28935.1 - 0.12 12.7 0.4 0.82 10.0 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4878) Aminotran_1_2 PF00155.21 EGR28936.1 - 1.6e-48 165.7 0.0 1.8e-48 165.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGR28936.1 - 2.8e-05 22.8 0.0 4.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGR28936.1 - 0.025 13.9 0.0 0.038 13.3 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 EGR28936.1 - 0.12 11.3 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V DUF1131 PF06572.12 EGR28936.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1131) DUF2870 PF11069.8 EGR28937.1 - 3.7e-27 94.6 2.5 9.9e-27 93.2 2.5 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2870) Latarcin PF10279.9 EGR28937.1 - 0.036 14.5 0.1 0.2 12.1 0.1 2.2 1 1 0 1 1 1 0 Latarcin precursor tRNA-synt_1b PF00579.25 EGR28938.1 - 8.9e-70 235.3 0.2 1.2e-69 234.8 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Phosducin PF02114.16 EGR28939.1 - 1.1e-20 73.7 3.8 1.5e-20 73.3 3.8 1.2 1 0 0 1 1 1 1 Phosducin DUF2252 PF10009.9 EGR28940.1 - 0.14 11.2 7.1 0.18 10.9 7.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) RR_TM4-6 PF06459.12 EGR28940.1 - 3.5 7.4 20.3 4.9 6.9 20.3 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TRP PF06011.12 EGR28941.1 - 1.2e-07 30.8 29.3 2e-07 30.1 29.3 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel Chlam_PMP PF02415.17 EGR28941.1 - 0.0072 16.7 10.9 43 4.9 0.0 6.3 5 0 0 5 5 5 3 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Kelch_5 PF13854.6 EGR28942.1 - 7.5e-33 112.0 1.5 2e-05 24.5 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGR28942.1 - 9.1e-31 105.6 15.2 3.7e-12 46.1 0.2 7.2 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_3 PF13415.6 EGR28942.1 - 4.9e-28 96.8 7.5 5.6e-07 29.7 0.0 7.1 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EGR28942.1 - 2e-17 62.8 7.5 0.021 15.1 0.0 6.6 4 2 2 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EGR28942.1 - 1.4e-16 59.7 4.7 0.0032 17.4 0.0 6.6 6 0 0 6 6 6 4 Kelch motif Metallophos PF00149.28 EGR28942.1 - 6.9e-11 43.0 0.2 1.4e-09 38.7 0.0 2.9 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase Kelch_1 PF01344.25 EGR28942.1 - 2.3e-08 33.5 3.4 0.013 15.1 0.0 5.6 6 1 0 6 6 6 2 Kelch motif RAG2 PF03089.14 EGR28942.1 - 2.8e-07 29.8 0.4 0.031 13.3 0.0 3.8 3 1 1 4 4 4 2 Recombination activating protein 2 STPPase_N PF16891.5 EGR28942.1 - 0.00025 21.4 0.3 0.00058 20.2 0.3 1.7 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain DUF5072 PF16807.5 EGR28942.1 - 0.082 13.0 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5072) AAA PF00004.29 EGR28943.1 - 2.8e-84 280.2 0.0 2.6e-49 167.0 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGR28943.1 - 1.8e-19 69.2 0.0 4.9e-09 35.8 0.0 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_5 PF07728.14 EGR28943.1 - 1.2e-12 48.1 0.0 0.00015 21.8 0.0 4.2 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGR28943.1 - 2.6e-12 47.5 0.0 0.00047 20.6 0.0 3.9 2 2 1 3 3 3 2 AAA ATPase domain AAA_14 PF13173.6 EGR28943.1 - 8.1e-11 42.1 0.3 0.00021 21.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain NACHT PF05729.12 EGR28943.1 - 1.1e-10 41.7 0.1 1.4e-05 25.1 0.0 3.9 2 2 1 3 3 3 2 NACHT domain AAA_2 PF07724.14 EGR28943.1 - 7.6e-10 39.2 0.2 3.9e-06 27.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGR28943.1 - 1.4e-09 37.8 0.0 0.00026 20.8 0.0 3.0 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EGR28943.1 - 2e-09 37.4 0.0 0.00014 21.7 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein TIP49 PF06068.13 EGR28943.1 - 6.5e-09 35.5 1.3 3.7e-05 23.1 0.0 2.6 3 0 0 3 3 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 EGR28943.1 - 1.8e-08 34.7 0.2 0.016 15.6 0.0 3.4 3 0 0 3 3 2 2 RNA helicase AAA_22 PF13401.6 EGR28943.1 - 2.4e-08 34.3 3.1 0.031 14.6 0.0 4.3 2 2 0 3 3 3 2 AAA domain Zeta_toxin PF06414.12 EGR28943.1 - 4.9e-08 32.5 0.0 0.0024 17.2 0.0 2.7 2 0 0 2 2 2 2 Zeta toxin AAA_18 PF13238.6 EGR28943.1 - 2.5e-07 31.3 0.2 0.014 16.0 0.0 3.4 3 0 0 3 3 3 2 AAA domain AAA_25 PF13481.6 EGR28943.1 - 2.6e-07 30.4 3.4 0.16 11.5 0.1 3.5 3 1 0 4 4 3 2 AAA domain DUF815 PF05673.13 EGR28943.1 - 7.5e-07 28.6 0.0 0.0064 15.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_33 PF13671.6 EGR28943.1 - 3.3e-06 27.3 0.0 0.0009 19.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain ATPase_2 PF01637.18 EGR28943.1 - 3.4e-06 27.1 11.1 0.087 12.7 0.0 5.2 3 2 1 5 5 5 2 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 EGR28943.1 - 4.9e-06 26.1 0.1 0.011 15.1 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 EGR28943.1 - 6.5e-06 25.4 0.7 0.038 13.1 0.2 2.4 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NTPase_1 PF03266.15 EGR28943.1 - 6.9e-06 26.1 0.4 0.42 10.5 0.0 4.1 4 0 0 4 4 3 1 NTPase ATPase PF06745.13 EGR28943.1 - 8.6e-06 25.3 0.1 1.5 8.1 0.0 3.5 3 0 0 3 3 3 2 KaiC AAA_3 PF07726.11 EGR28943.1 - 1.4e-05 24.9 0.0 0.1 12.4 0.0 3.0 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EGR28943.1 - 1.6e-05 25.4 0.9 0.25 11.9 0.0 3.4 3 0 0 3 3 2 2 ABC transporter Viral_helicase1 PF01443.18 EGR28943.1 - 1.9e-05 24.5 0.2 0.12 12.1 0.0 2.7 3 0 0 3 3 2 2 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 EGR28943.1 - 2.7e-05 23.7 0.2 0.28 10.7 0.0 2.9 3 0 0 3 3 2 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 EGR28943.1 - 3e-05 23.8 0.0 0.12 12.0 0.0 3.2 2 1 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 EGR28943.1 - 3.9e-05 23.7 0.0 0.15 12.1 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EGR28943.1 - 4.3e-05 22.8 0.8 0.19 10.9 0.0 2.9 3 0 0 3 3 2 2 NB-ARC domain KAP_NTPase PF07693.14 EGR28943.1 - 9.4e-05 21.8 0.0 0.088 12.0 0.0 2.8 2 1 1 3 3 3 1 KAP family P-loop domain AAA_28 PF13521.6 EGR28943.1 - 0.00012 22.3 0.1 0.27 11.4 0.0 3.0 2 1 0 2 2 2 1 AAA domain PhoH PF02562.16 EGR28943.1 - 0.00019 20.9 0.0 0.12 11.8 0.0 2.8 2 0 0 2 2 2 1 PhoH-like protein Bac_DnaA PF00308.18 EGR28943.1 - 0.00061 19.7 0.1 0.9 9.3 0.0 2.9 3 0 0 3 3 2 1 Bacterial dnaA protein Rad17 PF03215.15 EGR28943.1 - 0.00073 19.5 2.0 1.7 8.5 0.1 3.5 4 1 0 4 4 3 2 Rad17 P-loop domain AAA_11 PF13086.6 EGR28943.1 - 0.00088 19.1 9.5 1.2 8.9 0.0 3.4 2 1 1 3 3 3 1 AAA domain DnaB_C PF03796.15 EGR28943.1 - 0.00092 18.6 0.2 0.31 10.3 0.0 3.4 2 1 1 3 3 3 1 DnaB-like helicase C terminal domain AAA_24 PF13479.6 EGR28943.1 - 0.0011 18.7 0.0 0.72 9.5 0.0 2.8 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 EGR28943.1 - 0.0023 17.6 0.0 1.4 8.5 0.0 2.4 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.6 EGR28943.1 - 0.0029 17.9 0.3 2.4 8.5 0.2 3.0 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGR28943.1 - 0.0046 16.7 0.0 0.39 10.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain Sigma54_activ_2 PF14532.6 EGR28943.1 - 0.0083 16.3 0.0 3.1 7.9 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain DUF2075 PF09848.9 EGR28943.1 - 0.0092 15.3 4.7 0.12 11.6 0.0 2.9 3 0 0 3 3 2 1 Uncharacterized conserved protein (DUF2075) PduV-EutP PF10662.9 EGR28943.1 - 0.011 15.4 0.0 3.2 7.5 0.0 2.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 EGR28943.1 - 0.015 15.1 0.0 4.1 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EGR28943.1 - 0.016 15.1 0.1 0.2 11.5 0.0 2.5 3 0 0 3 3 2 0 Adenylylsulphate kinase AAA_17 PF13207.6 EGR28943.1 - 0.016 15.6 6.2 2 8.9 0.0 4.2 4 1 0 4 4 3 0 AAA domain ResIII PF04851.15 EGR28943.1 - 0.021 14.8 4.9 0.86 9.6 0.0 3.6 2 1 1 3 3 3 0 Type III restriction enzyme, res subunit MCM PF00493.23 EGR28943.1 - 0.04 13.0 0.1 2.9 6.9 0.0 3.0 2 1 0 2 2 2 0 MCM P-loop domain Zot PF05707.12 EGR28943.1 - 0.047 13.3 0.0 4.6 6.8 0.0 3.5 2 2 1 3 3 3 0 Zonular occludens toxin (Zot) AAA_23 PF13476.6 EGR28943.1 - 0.5 10.8 0.0 0.5 10.8 0.0 4.2 4 1 0 4 4 3 0 AAA domain Cytidylate_kin2 PF13189.6 EGR28943.1 - 0.55 10.3 3.3 11 6.1 0.0 2.7 3 0 0 3 3 2 0 Cytidylate kinase-like family Hydrolase_3 PF08282.12 EGR28943.1 - 2 8.1 10.0 0.62 9.7 5.8 2.3 3 0 0 3 3 2 0 haloacid dehalogenase-like hydrolase SecA_DEAD PF07517.14 EGR28944.1 - 0.035 13.4 0.2 0.048 13.0 0.2 1.2 1 0 0 1 1 1 0 SecA DEAD-like domain Peptidase_M57 PF12388.8 EGR28944.1 - 0.087 12.4 0.5 0.093 12.3 0.5 1.2 1 0 0 1 1 1 0 Dual-action HEIGH metallo-peptidase DUF960 PF06124.11 EGR28944.1 - 1.3 9.7 11.8 2.7 8.7 4.3 2.2 2 0 0 2 2 2 0 Staphylococcal protein of unknown function (DUF960) UPF0113_N PF17833.1 EGR28945.1 - 3.1e-29 101.4 1.4 4.1e-29 101.0 0.6 1.6 2 0 0 2 2 2 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EGR28945.1 - 2.2e-22 79.1 0.1 3.5e-22 78.4 0.1 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain RNA_pol_Rpc4 PF05132.14 EGR28947.1 - 0.37 11.2 8.8 0.37 11.2 8.8 1.0 1 0 0 1 1 1 0 RNA polymerase III RPC4 DNA_pol_phi PF04931.13 EGR28947.1 - 0.48 8.5 42.1 0.47 8.5 42.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi CobT PF06213.12 EGR28947.1 - 3.9 6.8 31.7 4.2 6.7 31.7 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SspB PF04386.13 EGR28947.1 - 6.8 6.6 15.4 7.2 6.5 15.4 1.1 1 0 0 1 1 1 0 Stringent starvation protein B V_ATPase_I PF01496.19 EGR28947.1 - 9.1 4.1 12.8 8.6 4.1 12.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4580 PF15162.6 EGR28948.1 - 0.0095 15.5 2.4 0.0095 15.5 2.4 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4580) zf_CopZ PF18423.1 EGR28948.1 - 0.087 12.8 2.8 1.6 8.7 0.4 2.5 2 0 0 2 2 2 0 Zinc binding domain ATP_Ca_trans_C PF12424.8 EGR28948.1 - 3.3 8.3 5.8 18 5.9 0.9 2.5 2 0 0 2 2 2 0 Plasma membrane calcium transporter ATPase C terminal CENP-F_leu_zip PF10473.9 EGR28949.1 - 0.00083 19.4 16.5 0.17 11.9 5.9 2.2 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 EGR28949.1 - 0.026 13.9 14.4 0.36 10.1 14.5 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 EGR28949.1 - 0.039 14.0 8.7 0.47 10.5 4.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) MRJP PF03022.16 EGR28949.1 - 0.039 13.3 1.0 0.042 13.2 1.0 1.2 1 0 0 1 1 1 0 Major royal jelly protein Fibritin_C PF07921.12 EGR28949.1 - 0.047 13.8 1.5 0.2 11.8 0.4 2.3 2 1 0 2 2 2 0 Fibritin C-terminal region Sas6_CC PF18594.1 EGR28949.1 - 0.05 13.4 6.9 2.4 8.0 0.2 3.9 3 1 1 4 4 4 0 Sas6/XLF/XRCC4 coiled-coil domain DUF4164 PF13747.6 EGR28949.1 - 0.051 13.9 8.5 0.044 14.0 5.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) SAM_KSR1 PF13543.6 EGR28949.1 - 0.06 13.5 6.1 0.03 14.4 3.2 2.0 1 1 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 Spc7 PF08317.11 EGR28949.1 - 0.06 12.2 14.6 0.32 9.8 14.0 1.8 1 1 1 2 2 2 0 Spc7 kinetochore protein JAKMIP_CC3 PF16034.5 EGR28949.1 - 0.067 13.1 13.0 0.11 12.5 13.0 1.4 1 1 0 1 1 1 0 JAKMIP CC3 domain APG6_N PF17675.1 EGR28949.1 - 0.079 13.5 14.7 0.04 14.4 12.0 1.7 1 1 1 2 2 2 0 Apg6 coiled-coil region FapA PF03961.13 EGR28949.1 - 0.082 11.5 12.1 0.18 10.3 12.1 1.6 1 1 0 1 1 1 0 Flagellar Assembly Protein A PI3K_P85_iSH2 PF16454.5 EGR28949.1 - 0.086 12.4 14.5 0.39 10.3 3.3 2.1 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DivIC PF04977.15 EGR28949.1 - 0.095 12.5 12.3 0.28 11.0 1.0 3.2 1 1 1 3 3 3 0 Septum formation initiator DUF4407 PF14362.6 EGR28949.1 - 0.11 11.8 6.0 0.16 11.3 6.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_13 PF13166.6 EGR28949.1 - 0.12 11.0 10.9 0.18 10.4 10.9 1.3 1 1 0 1 1 1 0 AAA domain DUF2968 PF11180.8 EGR28949.1 - 0.13 11.8 13.1 0.6 9.7 12.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) NRBF2 PF08961.10 EGR28949.1 - 0.14 11.7 7.0 0.24 11.0 6.2 1.6 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator TPR_MLP1_2 PF07926.12 EGR28949.1 - 0.19 11.8 13.3 2.9 8.0 13.2 2.2 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 EGR28949.1 - 0.21 11.6 15.4 0.29 11.2 7.1 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4618 PF15397.6 EGR28949.1 - 0.25 10.7 15.3 0.73 9.2 14.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) ZapD PF07072.11 EGR28949.1 - 0.25 11.1 7.2 0.37 10.5 7.2 1.4 1 1 0 1 1 1 0 Cell division protein DUF5082 PF16888.5 EGR28949.1 - 0.26 11.6 10.6 0.46 10.8 3.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) Baculo_PEP_C PF04513.12 EGR28949.1 - 0.28 11.2 7.0 0.79 9.8 5.5 2.0 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Helo_like_N PF17111.5 EGR28949.1 - 0.3 10.4 8.9 0.58 9.5 3.5 2.1 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins Jnk-SapK_ap_N PF09744.9 EGR28949.1 - 0.36 11.1 16.3 0.37 11.0 8.9 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Cep57_MT_bd PF06657.13 EGR28949.1 - 0.36 11.3 13.0 4.5 7.8 4.8 2.4 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 FAM76 PF16046.5 EGR28949.1 - 0.38 10.1 14.2 0.26 10.6 11.5 1.8 1 1 1 2 2 2 0 FAM76 protein HIP1_clath_bdg PF16515.5 EGR28949.1 - 0.42 11.2 15.6 0.19 12.4 9.4 2.3 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 JIP_LZII PF16471.5 EGR28949.1 - 0.47 10.7 13.0 0.29 11.3 0.5 3.0 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II UPF0242 PF06785.11 EGR28949.1 - 0.56 10.3 13.7 0.72 9.9 13.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF4140 PF13600.6 EGR28949.1 - 0.56 10.7 4.1 5 7.6 4.1 2.2 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) bZIP_2 PF07716.15 EGR28949.1 - 1.2 9.3 13.8 0.11 12.6 1.9 3.4 1 1 1 3 3 3 0 Basic region leucine zipper ZapB PF06005.12 EGR28949.1 - 1.4 9.4 14.5 3.5e+02 1.7 14.3 2.7 1 1 0 1 1 1 0 Cell division protein ZapB UCH PF00443.29 EGR28949.1 - 1.8 8.0 5.2 2 7.9 5.2 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase TMPIT PF07851.13 EGR28949.1 - 3.4 6.8 10.5 0.88 8.7 5.3 1.9 1 1 1 2 2 2 0 TMPIT-like protein Tup_N PF08581.10 EGR28949.1 - 3.6 7.9 13.1 2 8.7 9.8 2.1 1 1 0 2 2 2 0 Tup N-terminal HALZ PF02183.18 EGR28949.1 - 4.5 7.6 15.1 0.6 10.4 0.4 4.2 2 1 3 5 5 5 0 Homeobox associated leucine zipper Tho2 PF11262.8 EGR28949.1 - 5.2 6.2 11.4 11 5.1 11.4 1.8 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF5320 PF17253.2 EGR28949.1 - 5.5 8.1 12.3 18 6.5 3.6 3.3 1 1 2 3 3 3 0 Family of unknown function (DUF5320) bZIP_1 PF00170.21 EGR28949.1 - 6.8 6.9 13.6 2.9 8.0 1.9 3.1 1 1 2 3 3 3 0 bZIP transcription factor Spc24 PF08286.11 EGR28949.1 - 9.3 6.6 13.0 4.1 7.7 4.6 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Mpp10 PF04006.12 EGR28950.1 - 2e-61 208.3 105.9 6.2e-59 200.0 105.9 2.2 1 1 0 1 1 1 1 Mpp10 protein Adap_comp_sub PF00928.21 EGR28951.1 - 1.2e-83 280.5 3.9 1.5e-83 280.3 3.9 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 EGR28951.1 - 0.053 13.0 0.1 0.089 12.2 0.1 1.3 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain DUF2683 PF10884.8 EGR28951.1 - 1.3 9.4 5.1 1.1 9.6 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2683) Pkinase PF00069.25 EGR28952.1 - 1.1e-60 205.2 0.2 2.2e-60 204.3 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28952.1 - 3e-32 111.9 0.0 5.3e-32 111.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR28952.1 - 1.2e-05 24.8 1.9 0.0004 19.8 0.0 2.7 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 EGR28952.1 - 1.3e-05 24.2 0.0 2.8e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase SHIPPO-rpt PF07004.12 EGR28953.1 - 0.011 16.6 0.0 0.017 16.1 0.0 1.4 1 0 0 1 1 1 0 Sperm-tail PG-rich repeat DOMON PF03351.17 EGR28954.1 - 1.1e-06 28.9 0.2 1.7e-06 28.2 0.2 1.3 1 0 0 1 1 1 1 DOMON domain DUF4620 PF15399.6 EGR28954.1 - 0.26 11.6 0.0 0.38 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4620) DOMON PF03351.17 EGR28955.1 - 1.1e-11 45.0 0.6 1.8e-11 44.3 0.6 1.3 1 0 0 1 1 1 1 DOMON domain CDH-cyt PF16010.5 EGR28955.1 - 0.0037 17.0 0.8 0.0081 15.9 0.2 1.7 1 1 1 2 2 2 1 Cytochrome domain of cellobiose dehydrogenase CLTH PF10607.9 EGR28956.1 - 5.9e-26 91.1 12.7 5.9e-26 91.1 12.7 2.3 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain ALMT PF11744.8 EGR28956.1 - 0.75 8.6 12.8 1.1 8.0 12.8 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Sigma54_activ_2 PF14532.6 EGR28957.1 - 0.088 12.9 0.1 0.088 12.9 0.1 2.7 2 1 1 3 3 3 0 Sigma-54 interaction domain SNF2_N PF00176.23 EGR28958.1 - 2.7e-17 62.5 0.0 2.7e-17 62.5 0.0 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGR28958.1 - 1.5e-15 57.5 0.2 6.5e-15 55.4 0.2 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Tau95 PF09734.9 EGR28959.1 - 1.5e-09 38.8 0.2 1.5e-09 38.8 0.2 2.3 2 1 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain WD40 PF00400.32 EGR28960.1 - 0.0039 18.0 0.2 0.2 12.6 0.1 3.2 3 1 1 4 4 4 1 WD domain, G-beta repeat Borrelia_orfD PF02999.14 EGR28960.1 - 0.042 14.2 0.2 0.098 13.0 0.2 1.6 1 0 0 1 1 1 0 Borrelia orf-D family Peptidase_M8 PF01457.16 EGR28962.1 - 1.1e-32 113.5 5.3 5.1e-29 101.3 0.0 2.2 1 1 1 2 2 2 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR28962.1 - 0.0044 17.0 6.9 0.0044 17.0 6.9 3.2 3 0 0 3 3 3 1 Tenascin EGF domain EGF_2 PF07974.13 EGR28962.1 - 0.0072 16.7 7.9 0.0072 16.7 7.9 4.6 3 1 1 4 4 4 1 EGF-like domain Tobravirus_2B PF05271.11 EGR28962.1 - 0.12 12.3 0.4 0.3 11.0 0.4 1.6 1 0 0 1 1 1 0 Tobravirus 2B protein Peptidase_M8 PF01457.16 EGR28963.1 - 3.9e-20 72.0 0.7 4.1e-20 71.9 0.7 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 EGR28964.1 - 1.2e-35 123.2 4.4 1.6e-32 112.9 0.0 2.3 1 1 1 2 2 2 2 Leishmanolysin VSP PF03302.13 EGR28964.1 - 0.00082 18.3 20.5 0.00082 18.3 20.5 1.9 1 1 1 2 2 2 1 Giardia variant-specific surface protein EGF_Tenascin PF18720.1 EGR28964.1 - 5.1 7.3 14.6 1.4 9.1 9.9 2.7 2 0 0 2 2 2 0 Tenascin EGF domain MORN PF02493.20 EGR28965.1 - 1.6e-25 87.4 40.5 2.2e-05 24.1 0.4 5.7 5 1 0 5 5 5 5 MORN repeat Ammonium_transp PF00909.21 EGR28966.1 - 2.4e-48 164.8 9.8 2.6e-48 164.7 9.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family GWT1 PF06423.12 EGR28966.1 - 0.039 14.1 2.4 0.095 12.8 1.2 1.9 2 0 0 2 2 2 0 GWT1 Dpy-30 PF05186.13 EGR28967.1 - 2.4e-07 30.3 1.9 2.4e-07 30.3 0.6 1.7 2 0 0 2 2 2 1 Dpy-30 motif RE_Bsp6I PF09504.10 EGR28968.1 - 0.0087 15.7 0.7 0.077 12.6 0.6 2.1 1 1 0 2 2 2 1 Bsp6I restriction endonuclease HTH_10 PF04967.12 EGR28968.1 - 0.12 12.2 0.1 0.33 10.8 0.1 1.7 1 1 0 1 1 1 0 HTH DNA binding domain Pept_tRNA_hydro PF01195.19 EGR28970.1 - 6.9e-28 97.7 1.7 3.4e-21 75.9 0.4 2.7 1 1 1 2 2 2 2 Peptidyl-tRNA hydrolase DUF4179 PF13786.6 EGR28970.1 - 3.7 8.1 7.9 2.8 8.5 0.6 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4179) Cyto_heme_lyase PF01265.17 EGR28972.1 - 8.2 5.9 15.7 9.7 5.7 15.7 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase Histone_H2A_C PF16211.5 EGR28973.1 - 9.9e-18 63.6 0.4 2e-17 62.6 0.4 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGR28973.1 - 1.7e-14 54.3 0.0 2.4e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGR28973.1 - 2e-06 28.0 0.0 3.3e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TTL PF03133.15 EGR28974.1 - 5e-39 134.2 8.3 5e-39 134.2 8.3 2.0 3 0 0 3 3 3 1 Tubulin-tyrosine ligase family Sad1_UNC PF07738.13 EGR28974.1 - 0.038 14.0 2.0 7.2 6.6 0.9 2.8 1 1 1 2 2 2 0 Sad1 / UNC-like C-terminal Band_7 PF01145.25 EGR28975.1 - 9.5e-07 29.0 0.7 9.5e-07 29.0 0.7 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family Nkap_C PF06047.11 EGR28975.1 - 0.034 14.3 3.2 0.09 12.9 3.2 1.7 1 0 0 1 1 1 0 NF-kappa-B-activating protein C-terminal domain LsmAD PF06741.13 EGR28975.1 - 0.065 13.8 1.5 0.21 12.2 1.5 1.9 1 1 0 1 1 1 0 LsmAD domain APG5 PF04106.12 EGR28975.1 - 0.13 11.9 1.9 0.15 11.7 1.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg5 V-ATPase_G PF03179.15 EGR28975.1 - 0.33 11.5 10.1 0.12 12.9 7.1 1.8 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Pkinase PF00069.25 EGR28976.1 - 4.2e-67 226.3 0.1 7.2e-67 225.5 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28976.1 - 1.4e-36 126.2 0.0 2.2e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 EGR28976.1 - 5.8e-08 33.1 0.0 1.6e-07 31.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGR28976.1 - 1.5e-06 28.7 0.1 3.7e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGR28976.1 - 1.5e-05 25.2 0.2 0.049 14.1 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EGR28976.1 - 2.3e-05 24.4 0.1 0.0031 17.9 0.0 3.0 3 0 0 3 3 2 1 Ankyrin repeat Kinase-like PF14531.6 EGR28976.1 - 0.00023 20.6 0.0 0.0017 17.7 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Ank_5 PF13857.6 EGR28976.1 - 0.0012 19.1 0.0 0.0046 17.2 0.0 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Haspin_kinase PF12330.8 EGR28976.1 - 0.0015 17.6 5.4 0.0034 16.4 5.4 1.5 1 1 0 1 1 1 1 Haspin like kinase domain NAD_binding_6 PF08030.12 EGR28976.1 - 0.026 14.6 0.5 0.055 13.6 0.3 1.7 2 0 0 2 2 2 0 Ferric reductase NAD binding domain Kdo PF06293.14 EGR28976.1 - 0.047 13.0 0.2 0.1 11.9 0.1 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family EMP24_GP25L PF01105.24 EGR28977.1 - 0.0001 22.3 3.8 0.00059 19.8 0.0 2.0 1 1 0 2 2 2 2 emp24/gp25L/p24 family/GOLD Mito_carr PF00153.27 EGR28978.1 - 4.1e-09 36.2 1.0 0.00085 19.2 0.0 2.3 2 1 0 2 2 2 2 Mitochondrial carrier protein TPR_7 PF13176.6 EGR28979.1 - 0.13 12.4 0.2 7.9 6.8 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat SF3b1 PF08920.10 EGR28980.1 - 5.3e-34 117.2 12.9 2.3e-29 102.3 7.6 2.7 1 1 1 2 2 2 2 Splicing factor 3B subunit 1 HEAT_2 PF13646.6 EGR28980.1 - 6.1e-11 42.6 0.3 0.39 11.1 0.0 7.2 6 2 2 8 8 8 4 HEAT repeats HEAT PF02985.22 EGR28980.1 - 7.2e-11 41.4 1.4 0.45 10.9 0.0 8.2 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 EGR28980.1 - 3.1e-07 30.7 1.0 0.19 12.3 0.0 7.5 9 0 0 9 9 9 1 HEAT-like repeat Cnd1 PF12717.7 EGR28980.1 - 5.3e-07 29.8 2.4 3.1 7.8 0.2 6.0 4 2 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 UME PF08064.13 EGR28980.1 - 0.0018 18.1 3.6 0.93 9.4 0.0 4.6 5 1 0 5 5 5 2 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 EGR28980.1 - 0.0037 17.8 3.9 1.5 9.4 0.0 5.3 6 0 0 6 6 6 1 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EGR28981.1 - 3e-78 263.7 30.7 5.3e-78 262.9 30.7 1.4 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EGR28981.1 - 3.3e-29 102.0 5.4 3.3e-29 102.0 5.4 2.8 3 0 0 3 3 2 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EGR28981.1 - 8.7e-20 71.0 0.8 4.3e-19 68.8 0.1 2.5 2 0 0 2 2 2 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EGR28981.1 - 1.2e-08 35.2 0.0 0.00012 22.4 0.0 4.8 5 1 0 6 6 5 1 HEAT repeats Cnd1 PF12717.7 EGR28981.1 - 3.2e-06 27.3 33.1 0.0018 18.4 1.5 5.1 3 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGR28981.1 - 0.0021 18.1 0.3 4.3 7.9 0.0 4.9 6 0 0 6 6 5 1 HEAT repeat DoxA PF07680.11 EGR28981.1 - 0.0024 17.8 0.7 0.16 11.8 0.2 3.1 2 0 0 2 2 2 1 TQO small subunit DoxA Xrn1_D3 PF18194.1 EGR28981.1 - 0.0092 16.1 3.6 0.022 14.8 0.1 3.4 3 0 0 3 3 3 1 Exoribonuclease 1 Domain-3 Arm PF00514.23 EGR28981.1 - 0.051 13.6 0.0 9.2 6.5 0.0 3.4 3 0 0 3 3 2 0 Armadillo/beta-catenin-like repeat HTH_Mga PF08280.11 EGR28981.1 - 0.062 13.3 4.5 0.43 10.7 0.2 3.2 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain B2-adapt-app_C PF09066.10 EGR28981.1 - 0.15 12.1 5.6 0.042 13.9 1.2 2.5 2 1 0 2 2 1 0 Beta2-adaptin appendage, C-terminal sub-domain HEAT_EZ PF13513.6 EGR28981.1 - 0.21 12.1 0.1 4.2 8.0 0.1 3.2 3 1 1 4 4 4 0 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGR28981.1 - 0.32 11.6 7.7 13 6.5 0.1 4.3 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region Spore_II_R PF09551.10 EGR28981.1 - 1.6 9.2 7.3 7.4 7.0 3.7 3.5 1 1 1 2 2 2 0 Stage II sporulation protein R (spore_II_R) Cpn10 PF00166.21 EGR28982.1 - 6.7e-22 77.4 0.1 7.5e-22 77.2 0.1 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit Cupin_3 PF05899.12 EGR28982.1 - 0.12 12.1 0.3 1.4 8.7 0.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF861) Radical_SAM_C PF16199.5 EGR28983.1 - 9.5e-30 102.5 0.0 1.7e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EGR28983.1 - 5.6e-20 72.4 0.4 1.3e-19 71.1 0.1 1.7 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EGR28983.1 - 1.9e-10 41.0 0.1 3.7e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGR28983.1 - 6.5e-07 29.3 0.1 3.2e-06 27.1 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGR28983.1 - 0.00067 20.0 0.0 0.0013 19.1 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGR28983.1 - 0.012 15.6 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein BNR_6 PF15899.5 EGR28984.1 - 0.87 9.8 4.5 5.7 7.3 0.3 3.2 3 0 0 3 3 3 0 BNR-Asp box repeat PK PF00224.21 EGR28985.1 - 1.1e-82 277.7 5.6 1.6e-82 277.2 5.6 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EGR28985.1 - 2e-21 76.4 0.2 5.1e-21 75.1 0.2 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EGR28985.1 - 3.3e-05 23.1 0.2 5.2e-05 22.5 0.2 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Histone PF00125.24 EGR28986.1 - 1.5e-29 103.0 1.0 1.8e-29 102.8 1.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGR28986.1 - 4.2e-06 26.8 0.2 9.8e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGR28986.1 - 0.025 15.0 0.0 0.039 14.3 0.0 1.3 1 0 0 1 1 1 0 CENP-S protein E1_dh PF00676.20 EGR28988.1 - 1.9e-79 266.8 0.3 1.5e-78 263.8 0.3 1.9 1 1 0 1 1 1 1 Dehydrogenase E1 component SSPI PF14098.6 EGR28988.1 - 0.0033 17.5 0.2 0.007 16.5 0.2 1.5 1 0 0 1 1 1 1 Small, acid-soluble spore protein I DXP_synthase_N PF13292.6 EGR28988.1 - 0.06 12.5 0.5 0.41 9.8 0.0 2.2 2 1 1 3 3 3 0 1-deoxy-D-xylulose-5-phosphate synthase ATP_bind_1 PF03029.17 EGR28989.1 - 1.3e-62 211.7 0.1 1.5e-62 211.5 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.23 EGR28989.1 - 5.6e-05 23.2 0.0 7.3e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 EGR28989.1 - 0.00028 20.6 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGR28989.1 - 0.0015 18.9 0.0 0.0026 18.2 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGR28989.1 - 0.0026 18.0 0.0 0.008 16.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGR28989.1 - 0.0034 17.1 0.0 0.0074 16.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain PRK PF00485.18 EGR28989.1 - 0.004 16.9 0.0 0.0076 16.0 0.0 1.4 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EGR28989.1 - 0.0047 17.5 0.2 0.012 16.2 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_31 PF13614.6 EGR28989.1 - 0.0062 16.5 0.1 0.017 15.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EGR28989.1 - 0.0068 16.9 0.2 0.023 15.2 0.2 2.0 1 1 0 1 1 1 1 ABC transporter AAA_14 PF13173.6 EGR28989.1 - 0.0079 16.2 0.3 0.039 14.0 0.1 2.3 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.22 EGR28989.1 - 0.0097 15.5 0.0 0.018 14.7 0.0 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain PduV-EutP PF10662.9 EGR28989.1 - 0.0099 15.6 0.0 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 EGR28989.1 - 0.011 15.8 0.0 0.023 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EGR28989.1 - 0.017 15.5 0.1 0.11 12.9 0.0 2.1 1 1 1 2 2 2 0 RNA helicase AAA_7 PF12775.7 EGR28989.1 - 0.018 14.6 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_23 PF13476.6 EGR28989.1 - 0.032 14.7 2.0 0.09 13.3 2.1 2.0 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGR28989.1 - 0.053 12.6 0.0 0.079 12.0 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 EGR28989.1 - 0.054 12.9 0.0 0.096 12.1 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ArsA_ATPase PF02374.15 EGR28989.1 - 0.062 12.5 0.0 0.16 11.2 0.0 1.6 1 1 0 1 1 1 0 Anion-transporting ATPase ATPase_2 PF01637.18 EGR28989.1 - 0.063 13.2 2.1 0.76 9.6 0.1 2.8 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea Roc PF08477.13 EGR28989.1 - 0.069 13.4 0.0 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 EGR28989.1 - 0.081 13.1 0.1 0.1 12.8 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EGR28989.1 - 0.082 12.7 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 EGR28989.1 - 0.092 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 NACHT domain DUF87 PF01935.17 EGR28989.1 - 0.097 12.7 0.0 0.22 11.6 0.0 1.7 1 1 0 1 1 1 0 Helicase HerA, central domain AAA_28 PF13521.6 EGR28989.1 - 0.1 12.8 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGR28989.1 - 0.12 12.8 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) FeoB_N PF02421.18 EGR28989.1 - 0.12 11.9 0.1 1.1 8.7 0.1 2.4 2 1 0 2 2 2 0 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EGR28989.1 - 0.13 12.3 0.3 23 5.1 0.2 2.7 2 2 0 2 2 2 0 50S ribosome-binding GTPase NB-ARC PF00931.22 EGR28989.1 - 0.15 11.2 0.5 0.36 10.0 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_30 PF13604.6 EGR28989.1 - 0.17 11.6 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 EGR28990.1 - 4e-70 236.2 0.8 4e-70 236.2 0.8 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28990.1 - 1.1e-33 116.6 0.1 1.6e-33 116.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR28990.1 - 1.9e-06 27.1 2.6 3.9e-06 26.1 2.6 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGR28990.1 - 1.4e-05 24.6 0.3 2.6e-05 23.7 0.3 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGR28990.1 - 0.00094 18.6 0.4 0.00094 18.6 0.4 2.1 2 1 1 3 3 3 1 Kinase-like Pyrophosphatase PF00719.19 EGR28991.1 - 2.2e-58 196.6 1.5 2.7e-58 196.3 1.5 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase 14-3-3 PF00244.20 EGR28993.1 - 3.1e-41 141.3 4.7 3.4e-41 141.2 4.7 1.0 1 0 0 1 1 1 1 14-3-3 protein LcrG PF07216.12 EGR28993.1 - 0.0097 15.8 0.1 0.013 15.4 0.1 1.2 1 0 0 1 1 1 1 LcrG protein ATP-synt_DE PF00401.20 EGR28993.1 - 0.028 14.7 1.8 0.91 9.8 0.3 2.1 2 0 0 2 2 2 0 ATP synthase, Delta/Epsilon chain, long alpha-helix domain FIVAR PF07554.13 EGR28993.1 - 0.48 11.2 7.7 5.1 7.9 0.4 2.5 3 0 0 3 3 3 0 FIVAR domain Mito_carr PF00153.27 EGR28994.1 - 1.7e-12 47.1 0.3 2.1e-12 46.8 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial carrier protein Peptidase_S11 PF00768.20 EGR28995.1 - 1.8e-40 138.9 9.3 4.2e-21 75.5 0.4 2.5 3 0 0 3 3 3 2 D-alanyl-D-alanine carboxypeptidase Pkinase PF00069.25 EGR28996.1 - 8.1e-71 238.5 0.5 8.1e-71 238.5 0.5 3.1 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR28996.1 - 1.9e-42 145.3 7.1 1.6e-41 142.3 0.1 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Peptidase_S49 PF01343.18 EGR28998.1 - 1.7e-07 31.3 0.1 2.3e-07 30.9 0.1 1.1 1 0 0 1 1 1 1 Peptidase family S49 PHD PF00628.29 EGR29000.1 - 1.1e-08 34.8 44.5 5.3e-06 26.2 16.2 4.5 4 0 0 4 4 4 2 PHD-finger zf-HC5HC2H_2 PF13832.6 EGR29000.1 - 4.8e-06 26.7 5.1 4.8e-06 26.7 5.1 4.5 4 0 0 4 4 4 2 PHD-zinc-finger like domain Pkinase PF00069.25 EGR29001.1 - 7.7e-66 222.2 2.4 1.1e-65 221.7 2.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29001.1 - 1.4e-27 96.6 0.2 2e-27 96.1 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR29001.1 - 2.1e-06 27.2 0.0 5e-06 26.0 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR29001.1 - 1.4e-05 24.1 0.0 2e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR29001.1 - 3.9e-05 23.7 0.0 0.0047 16.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family FTA2 PF13095.6 EGR29001.1 - 0.0017 18.0 2.5 0.22 11.1 0.0 2.7 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 NAT PF04768.13 EGR29001.1 - 0.033 13.8 0.2 0.071 12.8 0.2 1.6 1 0 0 1 1 1 0 NAT, N-acetyltransferase, of N-acetylglutamate synthase RVT_connect PF06815.13 EGR29001.1 - 0.037 14.3 1.1 3.8 7.8 0.0 3.2 3 0 0 3 3 3 0 Reverse transcriptase connection domain Actin PF00022.19 EGR29002.1 - 8.8e-44 149.7 0.7 4.7e-23 81.5 0.0 2.2 2 0 0 2 2 2 2 Actin Kinesin PF00225.23 EGR29003.1 - 9.4e-90 300.9 2.6 9.4e-90 300.9 2.6 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGR29003.1 - 5.2e-28 97.9 1.9 5.2e-28 97.9 1.9 2.9 2 1 0 2 2 2 1 Microtubule binding FERM_M PF00373.18 EGR29003.1 - 0.35 11.3 5.5 1.1 9.6 5.5 2.1 1 1 0 1 1 1 0 FERM central domain TBCC PF07986.12 EGR29004.1 - 5.9e-33 113.2 4.8 1.4e-32 111.9 4.8 1.7 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 EGR29004.1 - 1.4e-14 54.5 18.2 1.4e-14 54.5 18.2 2.2 2 0 0 2 2 2 1 Tubulin-specific chaperone C N-terminal domain Retrotrans_gag PF03732.17 EGR29004.1 - 0.018 15.3 2.8 0.018 15.3 2.8 3.4 2 1 1 3 3 3 0 Retrotransposon gag protein DUF4407 PF14362.6 EGR29004.1 - 6.7 6.0 14.5 9.9 5.4 14.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DHHA1 PF02272.19 EGR29005.1 - 4.7e-06 27.1 0.9 1.3e-05 25.6 0.9 2.0 1 1 0 1 1 1 1 DHHA1 domain EF-hand_1 PF00036.32 EGR29006.1 - 3.1e-31 104.6 15.9 2.3e-09 36.1 1.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGR29006.1 - 4.1e-30 104.1 9.8 7.3e-15 55.2 2.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR29006.1 - 1.9e-23 80.4 11.3 2.5e-09 36.3 0.1 4.5 4 1 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGR29006.1 - 2.6e-22 78.4 9.6 2e-12 46.7 0.4 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_9 PF14658.6 EGR29006.1 - 2.8e-15 56.4 0.5 6.5e-08 32.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGR29006.1 - 9.4e-11 40.7 15.5 7.4e-05 22.1 1.4 4.3 4 2 0 4 4 4 3 EF hand EF-hand_4 PF12763.7 EGR29006.1 - 6.5e-05 22.8 4.5 0.14 12.1 0.2 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGR29006.1 - 0.00014 22.1 0.4 0.55 10.6 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF3008 PF11450.8 EGR29006.1 - 0.0062 16.7 0.7 0.015 15.4 0.2 1.9 2 0 0 2 2 2 1 Protein of unknwon function (DUF3008) SUB1_ProdP9 PF18213.1 EGR29006.1 - 0.015 15.1 0.1 0.04 13.7 0.1 1.8 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 EF-hand_14 PF17959.1 EGR29006.1 - 0.018 15.4 1.5 6 7.3 0.0 2.6 1 1 0 2 2 2 0 EF-hand domain SurA_N_2 PF13623.6 EGR29006.1 - 0.029 14.3 1.6 6 6.7 0.1 2.5 2 2 0 2 2 2 0 SurA N-terminal domain Acetyltransf_11 PF13720.6 EGR29006.1 - 0.047 14.1 0.3 1.4 9.4 0.1 2.3 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Dockerin_1 PF00404.18 EGR29006.1 - 0.049 13.8 0.3 7.2 6.9 0.0 2.6 2 1 0 2 2 2 0 Dockerin type I domain DUF853 PF05872.12 EGR29006.1 - 0.058 12.0 0.2 0.57 8.7 0.0 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) Caleosin PF05042.13 EGR29006.1 - 0.065 13.2 0.4 6.6 6.6 0.0 3.1 1 1 3 4 4 4 0 Caleosin related protein FlgD PF03963.14 EGR29006.1 - 0.076 13.3 0.2 0.16 12.3 0.2 1.7 1 1 0 1 1 1 0 Flagellar hook capping protein - N-terminal region SurA_N_3 PF13624.6 EGR29006.1 - 0.092 12.5 2.3 4.7 7.0 0.2 2.1 1 1 1 2 2 2 0 SurA N-terminal domain DUF21 PF01595.20 EGR29006.1 - 0.12 12.1 1.4 0.24 11.1 0.6 1.8 2 0 0 2 2 2 0 Cyclin M transmembrane N-terminal domain SRI PF08236.11 EGR29006.1 - 0.14 12.3 3.7 1.1 9.4 0.0 2.6 3 0 0 3 3 3 0 SRI (Set2 Rpb1 interacting) domain Peptidase_M24 PF00557.24 EGR29006.1 - 0.16 11.6 0.4 0.27 10.9 0.1 1.5 2 0 0 2 2 2 0 Metallopeptidase family M24 MgtE_N PF03448.17 EGR29006.1 - 0.4 11.3 5.2 0.46 11.1 1.1 2.3 2 0 0 2 2 2 0 MgtE intracellular N domain SHOCT PF09851.9 EGR29006.1 - 0.63 9.9 10.2 0.25 11.1 0.7 3.7 3 0 0 3 3 3 0 Short C-terminal domain PP2C PF00481.21 EGR29007.1 - 3e-40 138.5 0.0 3.6e-40 138.2 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C TGT PF01702.18 EGR29008.1 - 8.5e-122 406.7 0.0 1.1e-121 406.3 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Ribosomal_L44 PF00935.19 EGR29009.1 - 1.6e-28 99.0 12.7 1.6e-28 99.0 12.7 2.4 2 0 0 2 2 2 1 Ribosomal protein L44 Guanylate_cyc PF00211.20 EGR29009.1 - 3.2e-12 46.5 0.2 6.9e-12 45.4 0.2 1.6 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Rpr2 PF04032.16 EGR29009.1 - 0.97 9.8 9.6 0.18 12.1 4.6 2.4 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain UbiA PF01040.18 EGR29010.1 - 0.24 10.6 7.8 1.4 8.1 7.8 2.1 1 1 0 1 1 1 0 UbiA prenyltransferase family DUF4149 PF13664.6 EGR29010.1 - 2.6 8.4 12.1 0.17 12.2 2.7 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) Radial_spoke PF04712.12 EGR29011.1 - 7.7e-58 196.6 21.9 2.7e-42 145.4 6.8 2.5 1 1 1 2 2 2 2 Radial spokehead-like protein CENP-H PF05837.12 EGR29011.1 - 0.38 11.2 4.6 0.15 12.5 1.0 2.3 2 1 0 2 2 2 0 Centromere protein H (CENP-H) Proteasome PF00227.26 EGR29012.1 - 3.2e-50 170.3 0.0 4e-50 169.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit DSPc PF00782.20 EGR29013.1 - 1.6e-29 102.4 0.3 1.6e-29 102.4 0.3 1.6 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGR29013.1 - 0.0025 17.4 0.8 0.0049 16.5 0.0 1.7 1 1 1 2 2 2 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 EGR29013.1 - 0.024 14.3 0.0 0.038 13.7 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) GTP_EFTU PF00009.27 EGR29014.1 - 1.1e-42 145.8 0.0 2.4e-42 144.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGR29014.1 - 2.2e-20 72.5 0.0 5.6e-20 71.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EGR29014.1 - 6e-19 67.9 0.0 1.3e-18 66.8 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 EGR29014.1 - 3.7e-08 33.3 0.1 1.5e-07 31.3 0.1 2.0 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain EFG_IV PF03764.18 EGR29014.1 - 7.9e-08 32.1 0.1 0.00023 20.9 0.0 2.7 2 0 0 2 2 2 2 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 EGR29014.1 - 3.3e-07 30.6 0.1 8.8e-07 29.2 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGR29014.1 - 0.0067 16.5 0.0 0.023 14.8 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase NDK PF00334.19 EGR29015.1 - 2.7e-15 56.6 0.0 2.7e-15 56.6 0.0 2.3 3 0 0 3 3 3 1 Nucleoside diphosphate kinase HTH_6 PF01418.17 EGR29015.1 - 0.058 13.4 0.4 0.16 12.0 0.4 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain, rpiR family Siah-Interact_N PF09032.11 EGR29015.1 - 0.18 12.2 4.4 1.2 9.5 0.6 3.1 2 1 0 2 2 2 0 Siah interacting protein, N terminal HSF_DNA-bind PF00447.17 EGR29016.1 - 3.7e-30 104.4 5.0 5.6e-30 103.8 5.0 1.3 1 0 0 1 1 1 1 HSF-type DNA-binding Ets PF00178.22 EGR29016.1 - 0.02 15.4 0.4 0.051 14.0 0.4 1.9 1 1 0 1 1 1 0 Ets-domain Cation_ATPase_C PF00689.21 EGR29017.1 - 2.5e-42 144.7 8.4 2.5e-42 144.7 8.4 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGR29017.1 - 6.6e-37 126.8 0.4 6.6e-37 126.8 0.4 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGR29017.1 - 5.1e-23 81.0 0.0 1.2e-22 79.7 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGR29017.1 - 1.7e-16 61.2 0.1 1.2e-14 55.1 0.1 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGR29017.1 - 8.8e-10 38.1 0.1 2.1e-09 36.9 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGR29017.1 - 0.00014 21.7 3.2 0.00092 19.0 0.1 2.9 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGR29017.1 - 0.15 12.5 0.0 0.3 11.5 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Sds3 PF08598.11 EGR29018.1 - 0.085 12.9 64.4 0.26 11.2 26.7 3.9 1 1 1 2 2 2 0 Sds3-like Pox_A_type_inc PF04508.12 EGR29018.1 - 1.7 8.6 8.1 2.4 8.2 1.2 4.4 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat MDM10 PF12519.8 EGR29019.1 - 0.61 8.9 9.1 0.68 8.7 8.0 1.6 1 1 1 2 2 2 0 Mitochondrial distribution and morphology protein 10 Pkinase PF00069.25 EGR29021.1 - 7.8e-47 159.8 4.4 9.1e-47 159.6 4.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29021.1 - 4.1e-23 82.0 0.8 5.2e-23 81.6 0.8 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29021.1 - 9.5e-07 28.4 0.1 1.5e-06 27.8 0.0 1.3 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGR29021.1 - 0.0065 16.4 0.0 0.11 12.4 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family FAD_binding_1 PF00667.20 EGR29021.1 - 0.017 14.7 0.1 0.036 13.6 0.1 1.5 1 0 0 1 1 1 0 FAD binding domain Inj_translocase PF16928.5 EGR29021.1 - 0.025 14.0 0.9 0.025 14.0 0.9 1.5 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome Choline_kinase PF01633.20 EGR29021.1 - 0.034 13.7 3.9 0.11 12.1 3.9 1.9 1 1 0 1 1 1 0 Choline/ethanolamine kinase Ras PF00071.22 EGR29022.1 - 3.2e-51 173.1 3.2 7.1e-50 168.8 3.2 2.0 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGR29022.1 - 4.9e-27 94.5 1.4 4.9e-27 94.5 1.4 2.2 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR29022.1 - 2.1e-13 50.1 3.6 3.1e-11 43.0 3.6 2.2 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR29022.1 - 0.001 19.2 0.3 0.001 19.2 0.3 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGR29022.1 - 0.0015 17.9 6.0 0.0068 15.8 6.0 2.1 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Aconitase PF00330.20 EGR29023.1 - 1.2e-175 584.9 0.0 1.5e-175 584.6 0.0 1.0 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) zf-C2H2_2 PF12756.7 EGR29024.1 - 1.1e-22 80.2 41.7 2.4e-19 69.5 15.2 5.0 2 1 2 5 5 5 4 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EGR29024.1 - 1.9e-06 28.0 4.5 1.9e-06 28.0 4.5 4.3 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGR29024.1 - 3.1e-06 27.3 5.8 3.1e-06 27.3 5.8 5.7 5 1 0 5 5 5 2 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 EGR29024.1 - 1.1 10.3 25.9 0.3 12.0 0.6 5.5 6 0 0 6 6 6 0 C2H2-type zinc finger PRMT5_TIM PF17285.2 EGR29026.1 - 0.56 9.4 9.4 0.025 13.8 1.8 2.0 2 0 0 2 2 2 0 PRMT5 TIM barrel domain UPF0564 PF10595.9 EGR29028.1 - 2.9e-22 79.2 45.4 2.9e-22 79.2 45.4 5.8 3 1 2 5 5 5 1 Uncharacterised protein family UPF0564 DUF4090 PF13319.6 EGR29028.1 - 0.0073 16.5 12.0 3.1 8.1 0.1 6.3 5 2 1 6 6 6 1 Protein of unknown function (DUF4090) DUF4064 PF13273.6 EGR29029.1 - 0.00011 22.4 3.4 0.00017 21.8 1.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) DUF3302 PF11742.8 EGR29029.1 - 0.021 15.0 2.1 0.021 15.0 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3302) 7tm_3 PF00003.22 EGR29029.1 - 0.12 12.0 11.4 0.58 9.8 11.8 1.7 1 1 1 2 2 2 0 7 transmembrane sweet-taste receptor of 3 GCPR Ilm1 PF10311.9 EGR29029.1 - 0.21 11.2 6.8 0.64 9.7 6.8 1.7 1 1 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 Amnionless PF14828.6 EGR29029.1 - 0.84 8.4 1.9 0.51 9.1 0.2 1.5 1 1 0 2 2 2 0 Amnionless Bap31 PF05529.12 EGR29029.1 - 3.1 7.6 9.2 1.1 9.1 6.1 1.7 2 0 0 2 2 2 0 Bap31/Bap29 transmembrane region MLANA PF14991.6 EGR29029.1 - 3.5 7.9 4.2 1.3 9.3 0.1 2.1 1 1 1 2 2 2 0 Protein melan-A Tetraspanin PF00335.20 EGR29029.1 - 9.6 5.8 13.1 4.4 6.9 8.6 1.5 1 1 1 2 2 2 0 Tetraspanin family DUF4164 PF13747.6 EGR29030.1 - 0.00022 21.4 3.0 0.00037 20.7 3.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) Rab5-bind PF09311.11 EGR29030.1 - 0.0041 16.6 10.1 0.006 16.0 10.1 1.4 1 1 0 1 1 1 1 Rabaptin-like protein CENP-F_leu_zip PF10473.9 EGR29030.1 - 0.0081 16.2 5.9 0.0081 16.2 5.9 2.1 1 1 1 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2968 PF11180.8 EGR29030.1 - 0.009 15.7 10.1 0.011 15.4 10.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) DUF1664 PF07889.12 EGR29030.1 - 0.026 14.6 5.9 0.03 14.4 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ADIP PF11559.8 EGR29030.1 - 0.03 14.4 13.6 0.045 13.8 5.9 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding HIP1_clath_bdg PF16515.5 EGR29030.1 - 0.042 14.5 14.4 0.079 13.6 13.3 1.8 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Baculo_PEP_C PF04513.12 EGR29030.1 - 0.046 13.8 6.2 0.081 13.0 6.2 1.4 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1708 PF08101.11 EGR29030.1 - 0.066 12.4 2.5 0.071 12.3 2.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) PI3K_P85_iSH2 PF16454.5 EGR29030.1 - 0.07 12.7 11.0 0.2 11.3 6.6 2.0 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain SOGA PF11365.8 EGR29030.1 - 0.087 14.0 7.5 0.1 13.7 7.5 1.3 1 1 0 1 1 1 0 Protein SOGA APG6_N PF17675.1 EGR29030.1 - 0.12 12.9 12.6 0.31 11.6 12.5 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region NRBF2 PF08961.10 EGR29030.1 - 0.12 11.9 5.7 0.36 10.4 5.7 1.7 1 1 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator FAM76 PF16046.5 EGR29030.1 - 0.19 11.1 11.0 0.3 10.4 8.3 1.9 1 1 1 2 2 2 0 FAM76 protein HALZ PF02183.18 EGR29030.1 - 0.69 10.2 10.0 0.72 10.1 0.2 3.7 1 1 3 4 4 4 0 Homeobox associated leucine zipper Sas6_CC PF18594.1 EGR29030.1 - 0.96 9.3 8.2 1.4 8.8 0.3 3.7 3 1 1 4 4 4 0 Sas6/XLF/XRCC4 coiled-coil domain DUF4407 PF14362.6 EGR29030.1 - 1.1 8.6 5.5 1.2 8.4 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 EGR29030.1 - 1.1 9.0 8.1 0.68 9.8 0.5 2.7 1 1 1 2 2 2 0 Septum formation initiator DUF5320 PF17253.2 EGR29030.1 - 5 8.3 7.6 3.9 8.6 1.7 2.5 1 1 1 2 2 2 0 Family of unknown function (DUF5320) SlyX PF04102.12 EGR29030.1 - 6.7 7.4 10.9 40 4.9 9.2 2.6 1 1 1 2 2 2 0 SlyX SDA1 PF05285.12 EGR29031.1 - 0.0028 17.1 42.7 0.0035 16.8 42.7 1.1 1 0 0 1 1 1 1 SDA1 EF-hand_1 PF00036.32 EGR29033.1 - 1.7e-11 42.8 5.6 0.00038 19.8 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGR29033.1 - 1.9e-10 39.8 6.3 0.0059 16.4 0.1 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EGR29033.1 - 2.4e-08 34.3 4.8 4e-07 30.4 0.6 2.5 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGR29033.1 - 9.9e-06 24.8 2.5 0.0047 16.4 0.2 3.5 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EGR29033.1 - 3.9e-05 23.4 2.2 0.21 11.5 0.1 2.9 2 1 1 3 3 3 2 EF-hand domain pair MORN PF02493.20 EGR29035.1 - 2.6e-47 156.0 77.0 2.6e-08 33.3 2.2 10.2 10 0 0 10 10 10 9 MORN repeat Tudor_2 PF18104.1 EGR29035.1 - 0.0086 15.7 20.4 2.1 8.1 0.1 6.0 6 0 0 6 6 6 4 Jumonji domain-containing protein 2A Tudor domain PI3_PI4_kinase PF00454.27 EGR29036.1 - 1.4e-30 106.9 7.1 2.2e-29 103.0 1.3 3.1 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DnaJ PF00226.31 EGR29036.1 - 3.9e-22 78.2 1.5 3.9e-22 78.2 1.5 2.7 2 0 0 2 2 2 1 DnaJ domain ADK PF00406.22 EGR29037.1 - 1.1e-100 333.9 0.5 3.1e-49 167.0 0.1 2.6 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 EGR29037.1 - 1.7e-76 255.2 0.1 1.1e-36 126.2 0.0 2.7 2 0 0 2 2 2 2 AAA domain DUF4483 PF14825.6 EGR29037.1 - 5.3e-46 156.3 5.7 1.2e-45 155.2 5.7 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) Ribosomal_S3Ae PF01015.18 EGR29037.1 - 2.9e-17 62.9 3.9 2.9e-17 62.9 3.9 2.2 2 0 0 2 2 2 1 Ribosomal S3Ae family AAA_18 PF13238.6 EGR29037.1 - 3.3e-17 63.2 5.8 6e-08 33.3 0.0 3.2 4 0 0 4 4 2 2 AAA domain AAA_33 PF13671.6 EGR29037.1 - 1.7e-16 60.6 0.0 9.3e-07 29.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain Thymidylate_kin PF02223.17 EGR29037.1 - 1.3e-11 44.6 8.1 0.016 14.9 0.1 4.8 5 0 0 5 5 4 4 Thymidylate kinase Zeta_toxin PF06414.12 EGR29037.1 - 6.7e-10 38.6 0.1 0.00054 19.3 0.0 3.4 3 0 0 3 3 3 2 Zeta toxin AAA PF00004.29 EGR29037.1 - 8.6e-08 32.7 2.9 0.02 15.3 0.0 3.8 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 EGR29037.1 - 1e-05 25.4 4.2 0.083 12.6 0.0 3.4 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase SRP_SPB PF02978.19 EGR29037.1 - 7.5e-05 23.3 0.9 1.4 9.6 0.0 3.6 4 0 0 4 4 3 2 Signal peptide binding domain AAA_19 PF13245.6 EGR29037.1 - 0.00018 21.9 0.2 0.96 9.8 0.1 2.7 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.22 EGR29037.1 - 0.0007 18.9 0.4 1.1 8.4 0.0 3.4 3 1 1 4 4 4 2 NB-ARC domain Cytidylate_kin PF02224.18 EGR29037.1 - 0.00091 19.0 1.0 33 4.1 0.0 4.6 5 0 0 5 5 5 0 Cytidylate kinase RNA_helicase PF00910.22 EGR29037.1 - 0.00096 19.5 2.4 8.2 6.9 0.0 4.7 4 0 0 4 4 4 0 RNA helicase GvpK PF05121.12 EGR29037.1 - 0.0031 17.5 0.0 40 4.3 0.0 4.3 4 0 0 4 4 4 0 Gas vesicle protein K HTH_8 PF02954.19 EGR29037.1 - 0.0036 17.1 0.7 3.8 7.4 0.1 2.5 2 0 0 2 2 2 2 Bacterial regulatory protein, Fis family AAA_28 PF13521.6 EGR29037.1 - 0.0036 17.6 0.0 2.5 8.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Ploopntkinase3 PF18751.1 EGR29037.1 - 0.0076 16.2 0.0 5.6 6.8 0.0 2.8 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 NTPase_1 PF03266.15 EGR29037.1 - 0.01 15.7 0.1 4.9 7.0 0.0 2.6 2 0 0 2 2 2 0 NTPase ASPRs PF17641.2 EGR29037.1 - 0.014 15.7 2.3 24 5.3 0.0 3.9 3 0 0 3 3 3 0 Ancylostoma-associated secreted protein related NUP50 PF08911.11 EGR29037.1 - 0.014 16.0 0.5 12 6.6 0.0 2.7 2 0 0 2 2 2 0 NUP50 (Nucleoporin 50 kDa) AAA_22 PF13401.6 EGR29037.1 - 0.057 13.7 0.1 16 5.8 0.0 3.0 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 EGR29037.1 - 0.088 12.9 2.9 1.1 9.4 0.0 3.4 4 0 0 4 4 3 0 Torsin Hydrolase_3 PF08282.12 EGR29037.1 - 0.12 12.1 0.0 0.12 12.1 0.0 3.7 4 0 0 4 4 4 0 haloacid dehalogenase-like hydrolase pXO2-72 PF17443.2 EGR29037.1 - 0.21 11.8 2.4 32 4.9 0.1 3.4 3 0 0 3 3 2 0 Uncharacterized protein pXO2-72 ABC_tran PF00005.27 EGR29037.1 - 8.1 7.0 13.0 2.2 8.8 0.0 3.6 3 1 1 4 4 2 0 ABC transporter DUF2663 PF10864.8 EGR29038.1 - 0.0035 17.7 1.1 0.0042 17.5 1.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2663) TMEM192 PF14802.6 EGR29038.1 - 0.0082 15.3 4.5 0.01 15.0 4.5 1.0 1 0 0 1 1 1 1 TMEM192 family UPF0715 PF17094.5 EGR29038.1 - 0.071 13.7 10.1 0.078 13.5 10.1 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0715) Ac76 PF05814.11 EGR29038.1 - 0.36 10.9 5.1 0.46 10.5 3.3 1.9 1 1 1 2 2 2 0 Orf76 (Ac76) Fijivirus_P9-2 PF06837.11 EGR29038.1 - 7.6 5.9 12.3 12 5.3 12.3 1.3 1 1 0 1 1 1 0 Fijivirus P9-2 protein Ion_trans PF00520.31 EGR29039.1 - 8.6e-08 31.7 0.2 2e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Ion transport protein RRM_1 PF00076.22 EGR29040.1 - 2.9e-36 123.1 2.2 8.5e-18 64.0 0.1 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGR29040.1 - 3e-06 27.3 0.0 0.021 15.0 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif RRM_5 PF13893.6 EGR29040.1 - 1.8e-05 24.3 0.9 0.029 13.9 0.0 2.9 2 2 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 EGR29040.1 - 3.8e-05 23.6 0.0 0.26 11.3 0.0 2.7 2 0 0 2 2 2 2 RNA binding domain BRAP2 PF07576.12 EGR29040.1 - 0.0051 17.0 0.1 0.53 10.5 0.1 2.2 2 0 0 2 2 2 1 BRCA1-associated protein 2 Nup35_RRM PF05172.13 EGR29040.1 - 0.0065 16.4 0.3 0.47 10.5 0.0 2.4 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif WW PF00397.26 EGR29040.1 - 0.013 15.6 10.8 0.025 14.7 10.8 1.5 1 0 0 1 1 1 0 WW domain RRM_occluded PF16842.5 EGR29040.1 - 0.013 15.3 0.0 1.6 8.7 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif Pkinase PF00069.25 EGR29041.1 - 3e-21 76.0 0.0 3.3e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29041.1 - 3.3e-09 36.4 0.0 4.7e-09 35.9 0.0 1.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGR29042.1 - 3.2e-24 85.7 0.1 4e-24 85.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29042.1 - 3.7e-14 52.7 0.0 4.8e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4378 PF14309.6 EGR29043.1 - 0.016 15.6 5.8 0.41 11.0 5.8 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4378) DUF4387 PF14330.6 EGR29044.1 - 0.19 12.5 5.1 0.92 10.2 0.1 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4387) Memo PF01875.17 EGR29045.1 - 6.7e-54 182.9 0.0 1e-50 172.4 0.0 2.0 1 1 1 2 2 2 2 Memo-like protein WD40 PF00400.32 EGR29046.1 - 1.5e-52 174.4 17.1 6.8e-09 36.2 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR29046.1 - 1.9e-14 53.7 3.1 0.0097 16.2 0.1 4.6 2 2 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGR29046.1 - 1.3e-08 34.0 6.2 0.31 9.6 0.1 5.8 3 2 3 6 6 6 4 Nucleoporin Nup120/160 WD40_like PF17005.5 EGR29046.1 - 0.00028 20.3 1.1 1.3 8.3 0.1 3.0 2 1 1 3 3 3 3 WD40-like domain Nucleoporin_N PF08801.11 EGR29046.1 - 0.00051 18.9 6.3 0.089 11.5 0.2 4.2 1 1 1 3 3 3 2 Nup133 N terminal like Hydrolase_like PF13242.6 EGR29048.1 - 1.6e-09 37.7 0.0 2.1e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 EGR29048.1 - 0.0017 18.5 0.1 0.0034 17.5 0.0 1.5 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase MCH PF02289.16 EGR29048.1 - 0.0021 17.4 0.1 0.0023 17.3 0.1 1.0 1 0 0 1 1 1 1 Cyclohydrolase (MCH) Hydrolase PF00702.26 EGR29048.1 - 0.0038 17.5 0.0 0.0041 17.4 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase WD40 PF00400.32 EGR29049.1 - 3e-08 34.2 6.9 0.047 14.6 0.0 5.0 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF961 PF06125.11 EGR29049.1 - 9.3 6.7 8.8 0.33 11.3 0.5 2.8 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF961) HATPase_c PF02518.26 EGR29050.1 - 1.4e-20 73.8 0.3 4.3e-20 72.3 0.3 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGR29050.1 - 1.1e-15 57.8 0.1 2.4e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EGR29050.1 - 2.5e-07 30.6 0.3 6.6e-07 29.3 0.1 1.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EGR29050.1 - 0.00027 20.8 0.2 0.00049 19.9 0.2 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase NUMOD3 PF07460.11 EGR29050.1 - 0.2 11.9 0.4 0.44 10.8 0.4 1.5 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) Ion_trans PF00520.31 EGR29051.1 - 2.8e-07 30.0 5.6 5.5e-07 29.1 5.6 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGR29051.1 - 3e-07 30.3 10.3 9.4e-07 28.7 10.1 2.0 1 1 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 EGR29051.1 - 0.0048 16.9 0.0 0.0077 16.3 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain FliP PF00813.20 EGR29051.1 - 0.032 14.1 0.0 0.063 13.2 0.0 1.4 1 0 0 1 1 1 0 FliP family DUF5338 PF17273.2 EGR29051.1 - 0.14 12.3 5.0 0.72 10.0 0.3 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5338) HSP70 PF00012.20 EGR29052.1 - 6.9e-254 843.6 6.8 7.8e-254 843.4 6.8 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGR29052.1 - 2.5e-15 56.1 0.7 4.2e-13 48.8 0.1 2.2 2 0 0 2 2 2 2 MreB/Mbl protein BcrAD_BadFG PF01869.20 EGR29052.1 - 0.00035 20.2 0.1 0.06 12.8 0.0 2.3 2 0 0 2 2 2 2 BadF/BadG/BcrA/BcrD ATPase family FtsA PF14450.6 EGR29052.1 - 0.0012 19.2 2.7 1.7 9.1 0.0 3.5 3 2 0 3 3 3 2 Cell division protein FtsA Hydantoinase_A PF01968.18 EGR29052.1 - 0.017 14.4 0.6 0.11 11.7 0.4 2.2 1 1 1 2 2 2 0 Hydantoinase/oxoprolinase DDR PF08841.10 EGR29052.1 - 0.039 12.9 1.5 0.29 10.1 0.4 2.6 1 1 1 2 2 2 0 Diol dehydratase reactivase ATPase-like domain NYD-SP28 PF14772.6 EGR29052.1 - 0.18 11.9 6.2 0.044 13.8 1.6 2.1 1 1 1 2 2 2 0 Sperm tail DUF4854 PF16146.5 EGR29052.1 - 0.26 11.7 3.5 0.54 10.6 2.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4854) Uds1 PF15456.6 EGR29052.1 - 1.6 8.9 5.9 0.7 10.1 2.2 2.0 2 0 0 2 2 2 0 Up-regulated During Septation Pkinase PF00069.25 EGR29053.1 - 2.2e-30 105.9 0.5 2.6e-30 105.7 0.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29053.1 - 2.2e-20 73.1 0.1 2.8e-20 72.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29053.1 - 0.00054 19.4 0.1 0.0012 18.2 0.1 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR29053.1 - 0.0046 16.3 0.1 0.0069 15.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR29053.1 - 0.007 15.2 0.1 0.0089 14.8 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Rsa3 PF14615.6 EGR29054.1 - 7.6e-15 54.2 25.3 2.1 8.0 0.0 15.2 17 0 0 17 17 17 6 Ribosome-assembly protein 3 HTH_50 PF18024.1 EGR29054.1 - 0.00059 19.4 4.9 15 5.3 0.0 8.8 10 0 0 10 10 10 1 Helix-turn-helix domain DUF5503 PF17607.2 EGR29054.1 - 0.088 13.1 6.2 2.1 8.7 0.4 3.7 2 0 0 2 2 2 0 Family of unknown function (DUF5503) RPT PF13446.6 EGR29054.1 - 0.68 9.9 12.3 30 4.6 0.3 5.5 4 0 0 4 4 4 0 A repeated domain in UCH-protein Fez1 PF06818.15 EGR29054.1 - 3.2 8.1 299.7 0.2 12.1 19.4 13.6 1 1 12 13 13 13 0 Fez1 DUF3437 PF11919.8 EGR29054.1 - 3.9 7.5 7.0 27 4.8 0.0 5.7 6 0 0 6 6 6 0 Domain of unknown function (DUF3437) REJ PF02010.15 EGR29055.1 - 1.8e-12 46.8 9.1 4.2e-12 45.6 9.1 1.5 1 1 0 1 1 1 1 REJ domain HECW_N PF16562.5 EGR29055.1 - 0.025 14.4 0.2 0.066 13.0 0.2 1.7 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 FKBP_C PF00254.28 EGR29056.1 - 3.7e-27 94.5 0.0 4.9e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase EAP30 PF04157.16 EGR29057.1 - 3.6e-11 42.8 0.2 1.1e-07 31.4 0.0 2.2 1 1 1 2 2 2 2 EAP30/Vps36 family NIF3 PF01784.18 EGR29057.1 - 0.14 11.7 0.7 0.33 10.5 0.7 1.7 1 1 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) DUF2205 PF10224.9 EGR29058.1 - 3.1 7.8 6.5 2 8.5 0.3 2.9 2 1 1 3 3 3 0 Short coiled-coil protein DNA_topoisoIV PF00521.20 EGR29059.1 - 1.1e-130 436.4 6.1 1.1e-130 436.4 6.1 2.5 2 1 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EGR29059.1 - 1.8e-41 141.4 9.3 1.8e-41 141.4 9.3 2.3 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EGR29059.1 - 4.7e-23 81.5 2.9 1.6e-22 79.8 2.9 1.9 1 0 0 1 1 1 1 DNA gyrase B Toprim PF01751.22 EGR29059.1 - 4e-08 33.4 0.1 4.5e-07 30.0 0.0 2.7 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.26 EGR29060.1 - 2.4e-08 34.5 0.1 3.6e-08 33.9 0.1 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Furin-like_2 PF15913.5 EGR29062.1 - 0.00079 19.6 248.9 0.1 12.8 4.3 10.7 5 4 4 10 10 10 8 Furin-like repeat, cysteine-rich Pep3_Vps18 PF05131.14 EGR29063.1 - 9.2e-23 80.7 4.0 5.4e-22 78.2 1.5 3.3 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family zf-C3HC4 PF00097.25 EGR29063.1 - 0.00017 21.4 2.9 0.00077 19.3 2.9 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGR29063.1 - 0.00036 20.8 2.9 0.0016 18.7 2.9 2.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGR29063.1 - 0.001 18.9 3.0 0.0033 17.2 3.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGR29063.1 - 0.017 15.1 2.2 0.017 15.1 2.2 2.2 2 0 0 2 2 2 0 RING-type zinc-finger Vps39_2 PF10367.9 EGR29063.1 - 0.026 15.0 13.0 0.05 14.1 0.8 4.2 3 1 1 4 4 4 0 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 EGR29063.1 - 0.086 12.8 5.7 0.063 13.3 3.2 2.2 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 EGR29063.1 - 0.099 12.4 9.2 0.059 13.1 6.4 2.3 2 0 0 2 2 2 0 RING-like zinc finger ANAPC3 PF12895.7 EGR29063.1 - 0.3 11.3 6.2 8.3 6.7 1.8 3.2 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 Adhesin_P1_N PF18652.1 EGR29063.1 - 1.7 8.7 3.8 2.7 8.1 0.1 3.0 2 0 0 2 2 2 0 Adhesin P1 N-terminal domain Ribosomal_L6 PF00347.23 EGR29064.1 - 9.4e-23 80.7 0.2 4.7e-14 52.8 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Myb_DNA-binding PF00249.31 EGR29065.1 - 9.3e-28 96.2 4.2 1.7e-14 53.7 0.1 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGR29065.1 - 1.7e-22 79.5 6.1 1.6e-13 50.6 2.3 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGR29065.1 - 1.5e-07 31.2 1.0 3.5e-07 30.0 0.3 1.9 1 1 1 2 2 2 1 Myb DNA-binding like Myb_DNA-bind_4 PF13837.6 EGR29065.1 - 0.00063 20.1 5.3 0.0016 18.8 1.8 2.6 1 1 1 2 2 2 1 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 EGR29065.1 - 0.021 15.0 1.7 0.061 13.5 0.4 2.2 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 Sigma70_r4_2 PF08281.12 EGR29065.1 - 0.061 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 MADF_DNA_bdg PF10545.9 EGR29065.1 - 0.13 12.6 3.8 3.2 8.1 0.6 2.4 1 1 1 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like ECH_1 PF00378.20 EGR29066.1 - 2.1e-38 132.1 0.1 1.3e-37 129.4 0.1 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGR29066.1 - 2.3e-18 66.8 0.1 2.1e-14 53.8 0.0 2.1 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase Init_tRNA_PT PF04179.12 EGR29066.1 - 0.044 14.1 0.0 0.13 12.5 0.0 1.9 2 0 0 2 2 2 0 Rit1 DUSP-like domain Dapper PF15268.6 EGR29067.1 - 0.083 11.7 26.4 0.11 11.3 26.4 1.1 1 0 0 1 1 1 0 Dapper Glyco_hydro_125 PF06824.11 EGR29068.1 - 1.3e-151 505.2 2.7 1.5e-151 505.0 2.7 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) CUB_2 PF02408.20 EGR29068.1 - 0.016 15.0 1.3 0.072 12.9 0.0 2.7 4 0 0 4 4 4 0 CUB-like domain DUF627 PF04781.12 EGR29068.1 - 0.028 14.4 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF627) COX15-CtaA PF02628.15 EGR29070.1 - 1.5e-97 326.6 1.4 1.7e-97 326.4 1.4 1.0 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein RSN1_TM PF13967.6 EGR29070.1 - 0.046 13.5 0.1 0.11 12.2 0.1 1.7 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport Phostensin PF13914.6 EGR29070.1 - 0.05 14.2 0.0 0.1 13.2 0.0 1.6 1 1 0 1 1 1 0 Phostensin PP1-binding and SH3-binding region AAA_28 PF13521.6 EGR29071.1 - 2.6e-22 79.8 0.0 4.2e-22 79.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGR29071.1 - 0.038 13.7 0.6 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_18 PF13238.6 EGR29071.1 - 0.12 13.0 3.4 0.46 11.0 0.7 3.1 2 1 0 2 2 2 0 AAA domain Pex24p PF06398.11 EGR29072.1 - 7.4 5.5 12.6 9.3 5.1 12.6 1.1 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin PRK PF00485.18 EGR29073.1 - 7.9e-05 22.5 0.0 9.8e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EGR29073.1 - 0.0016 19.0 0.0 0.0033 18.0 0.0 1.6 2 0 0 2 2 2 1 AAA domain ABC_tran PF00005.27 EGR29073.1 - 0.0088 16.6 0.3 0.011 16.3 0.3 1.6 1 1 0 1 1 1 1 ABC transporter SRP54 PF00448.22 EGR29073.1 - 0.01 15.5 0.0 0.025 14.2 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 EGR29073.1 - 0.041 13.8 0.0 2.5 8.0 0.0 2.2 2 0 0 2 2 2 0 NTPase Thymidylate_kin PF02223.17 EGR29073.1 - 0.049 13.3 0.3 0.15 11.7 0.1 1.9 2 0 0 2 2 2 0 Thymidylate kinase ATP_bind_1 PF03029.17 EGR29073.1 - 0.13 12.0 0.1 0.37 10.5 0.1 1.7 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.6 EGR29073.1 - 0.22 11.2 0.0 0.79 9.4 0.0 1.7 2 0 0 2 2 2 0 AAA domain TTL PF03133.15 EGR29074.1 - 6.3e-09 35.4 0.3 7.3e-09 35.2 0.3 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_ST PF14397.6 EGR29074.1 - 0.00014 21.2 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp ATPgrasp_YheCD PF14398.6 EGR29074.1 - 0.00047 19.5 0.0 0.00054 19.3 0.0 1.1 1 0 0 1 1 1 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 EGR29074.1 - 0.016 14.7 0.1 0.025 14.1 0.1 1.3 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus R2K_2 PF18299.1 EGR29074.1 - 0.073 12.9 0.0 0.092 12.6 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 Rcd1 PF04078.13 EGR29075.1 - 9.6e-110 365.9 4.4 1.1e-109 365.7 4.4 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like TPR_19 PF14559.6 EGR29075.1 - 0.093 13.3 0.0 0.21 12.1 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat EF-hand_7 PF13499.6 EGR29076.1 - 8.4e-05 22.9 0.4 0.004 17.6 0.0 2.5 1 1 2 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EGR29076.1 - 0.0027 17.1 1.4 0.019 14.5 0.1 2.7 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 EGR29076.1 - 0.0035 17.1 0.4 0.041 13.7 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 EGR29076.1 - 0.0054 16.6 0.3 3.6 7.8 0.0 3.0 2 2 0 2 2 2 2 EF-hand domain PCI PF01399.27 EGR29077.1 - 1.2e-14 54.6 2.2 1.2e-14 54.6 2.2 2.8 2 2 0 2 2 2 1 PCI domain RPN5_C PF18098.1 EGR29077.1 - 1.9e-10 40.6 2.3 6.7e-10 38.9 2.3 2.1 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain NUC129 PF08157.11 EGR29077.1 - 0.085 13.2 0.1 0.29 11.5 0.1 1.9 1 0 0 1 1 1 0 NUC129 domain FA_hydroxylase PF04116.13 EGR29078.1 - 4.4e-27 95.0 14.1 4.4e-27 95.0 13.0 1.5 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Pkinase PF00069.25 EGR29079.1 - 2.4e-18 66.5 0.4 5.3e-18 65.3 0.2 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29079.1 - 1.8e-10 40.6 0.0 2.1e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR29079.1 - 0.0059 16.6 0.0 0.009 15.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGR29079.1 - 0.0071 15.2 0.0 0.0093 14.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase YukC PF10140.9 EGR29079.1 - 0.019 13.8 0.0 0.023 13.5 0.0 1.1 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Haspin_kinase PF12330.8 EGR29079.1 - 0.072 12.0 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Choline_kinase PF01633.20 EGR29079.1 - 0.073 12.6 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Peptidase_M8 PF01457.16 EGR29081.1 - 1e-35 123.5 0.2 1e-35 123.5 0.2 3.1 2 1 1 3 3 3 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR29081.1 - 3.9e-05 23.6 7.3 3.9e-05 23.6 7.3 3.7 3 0 0 3 3 3 1 Tenascin EGF domain Furin-like_2 PF15913.5 EGR29081.1 - 0.00066 19.8 14.7 0.00066 19.8 14.7 7.0 2 1 4 7 7 7 4 Furin-like repeat, cysteine-rich Fer2 PF00111.27 EGR29082.1 - 0.00042 20.2 0.0 0.00052 19.9 0.0 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain zf-RING_7 PF02591.15 EGR29082.1 - 0.074 13.2 0.0 1 9.6 0.0 2.2 2 0 0 2 2 2 0 C4-type zinc ribbon domain Pkinase PF00069.25 EGR29084.1 - 2.4e-43 148.4 3.6 3.1e-43 148.1 3.6 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29084.1 - 2.3e-21 76.3 1.0 3e-21 75.9 1.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29084.1 - 4.1e-06 26.3 0.0 5.4e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 EGR29084.1 - 0.006 16.1 0.5 0.006 16.1 0.5 1.7 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL Kdo PF06293.14 EGR29084.1 - 0.017 14.5 0.3 0.029 13.7 0.3 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kelch_4 PF13418.6 EGR29085.1 - 1.2e-22 79.7 2.4 1.3e-06 28.3 0.0 4.9 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EGR29085.1 - 9.9e-18 63.7 0.0 0.00041 20.3 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 EGR29085.1 - 3.5e-16 58.9 1.3 2.8e-05 24.2 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 EGR29085.1 - 7.3e-15 54.8 0.1 0.0012 19.0 0.0 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 EGR29085.1 - 1.2e-07 31.4 0.4 0.53 10.4 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.25 EGR29085.1 - 2.2e-06 27.2 0.0 0.7 9.5 0.0 4.8 5 0 0 5 5 5 2 Kelch motif PDEase_I PF00233.19 EGR29086.1 - 3.2e-84 282.4 7.6 3.2e-84 282.4 7.6 2.5 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase MaoC_dehydratas PF01575.19 EGR29088.1 - 1.2e-25 89.4 0.0 2.5e-25 88.4 0.0 1.5 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EGR29088.1 - 1.4e-07 31.7 0.0 1.5e-05 25.1 0.0 2.2 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase Pkinase PF00069.25 EGR29089.1 - 1.6e-32 112.9 0.1 1.6e-32 112.9 0.1 2.9 1 1 2 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29089.1 - 2.8e-19 69.4 0.7 5.8e-19 68.4 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase TFIIF_alpha PF05793.12 EGR29089.1 - 0.12 11.0 57.6 0.16 10.5 57.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Ins134_P3_kin PF05770.11 EGR29090.1 - 3.2e-32 111.7 0.6 6.4e-32 110.7 0.6 1.4 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGR29090.1 - 0.0027 17.3 0.5 0.0057 16.2 0.5 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Cys_rich_KTR PF14205.6 EGR29090.1 - 0.021 14.6 0.8 0.07 12.9 0.8 1.9 1 0 0 1 1 1 0 Cysteine-rich KTR Ins134_P3_kin_N PF17927.1 EGR29090.1 - 0.055 13.9 0.6 0.055 13.9 0.6 2.7 3 1 0 3 3 3 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain TMEM43 PF07787.12 EGR29091.1 - 4.2e-68 229.5 1.0 6.1e-68 228.9 1.0 1.3 1 0 0 1 1 1 1 Transmembrane protein 43 SKG6 PF08693.10 EGR29091.1 - 3.1 7.3 12.8 1.2 8.6 0.1 3.4 3 0 0 3 3 3 0 Transmembrane alpha-helix domain DUF2207 PF09972.9 EGR29091.1 - 7.4 5.2 13.4 5.4 5.7 8.5 2.6 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) TTL PF03133.15 EGR29093.1 - 4.2e-79 265.7 9.7 4.2e-79 265.7 9.7 2.3 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR29093.1 - 1.1e-07 31.3 5.9 2.6e-05 23.6 0.0 3.4 3 1 1 4 4 4 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR29093.1 - 1.5e-05 24.5 3.0 0.0032 16.8 0.0 2.8 3 1 0 3 3 3 2 Sugar-transfer associated ATP-grasp GARS_A PF01071.19 EGR29093.1 - 0.0023 17.7 0.0 0.0076 16.0 0.0 1.8 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain S-l_SbsC_C PF18316.1 EGR29093.1 - 0.63 10.6 3.9 14 6.2 0.1 2.6 2 0 0 2 2 2 0 S-layer protein SbsC C-terminal domain ORF6N PF10543.9 EGR29093.1 - 1.5 9.1 6.8 1.2 9.3 3.3 2.6 2 1 0 2 2 2 0 ORF6N domain DHHC PF01529.20 EGR29094.1 - 2.5e-38 131.2 16.1 3.3e-38 130.8 16.1 1.1 1 0 0 1 1 1 1 DHHC palmitoyltransferase MRAP PF15183.6 EGR29094.1 - 8.4 6.4 8.2 18 5.4 4.6 2.4 1 1 1 2 2 2 0 Melanocortin-2 receptor accessory protein family CDC45 PF02724.14 EGR29095.1 - 0.38 9.0 12.1 0.41 8.9 12.1 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EGR29095.1 - 7.2 4.7 18.0 8.1 4.5 18.0 1.0 1 0 0 1 1 1 0 Nop14-like family VSP PF03302.13 EGR29096.1 - 2.9e-14 52.8 188.8 4.1e-05 22.6 32.6 7.6 2 2 5 7 7 7 7 Giardia variant-specific surface protein Sec23_trunk PF04811.15 EGR29097.1 - 2.8e-34 118.8 1.9 1.5e-28 100.0 1.0 2.5 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EGR29097.1 - 7e-06 26.7 0.0 2.5e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Dopey_N PF04118.14 EGR29100.1 - 1.3e-77 260.9 10.1 1.3e-77 260.9 10.1 1.9 1 1 1 2 2 2 1 Dopey, N-terminal RRM_1 PF00076.22 EGR29101.1 - 0.00033 20.4 1.2 0.1 12.4 0.2 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) QSOX_Trx1 PF18108.1 EGR29101.1 - 0.015 15.5 0.9 0.072 13.3 0.2 2.7 2 1 0 2 2 2 0 QSOX Trx-like domain CUE PF02845.16 EGR29101.1 - 0.053 13.2 0.1 0.17 11.7 0.1 1.9 1 0 0 1 1 1 0 CUE domain IBR PF01485.21 EGR29102.1 - 2.5e-08 34.0 54.7 1.1e-06 28.8 12.6 4.9 3 2 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EGR29102.1 - 8e-06 25.6 9.1 8e-06 25.6 9.1 4.1 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGR29102.1 - 0.00011 22.5 9.4 0.00011 22.5 9.4 3.9 3 2 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGR29102.1 - 0.0011 18.7 12.0 0.0011 18.7 12.0 4.4 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGR29102.1 - 0.0017 18.3 5.1 0.0017 18.3 5.1 3.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-ribbon_3 PF13248.6 EGR29102.1 - 0.073 12.5 0.0 0.073 12.5 0.0 5.9 4 2 1 5 5 5 0 zinc-ribbon domain APG6_N PF17675.1 EGR29103.1 - 0.01 16.4 8.8 0.01 16.4 8.8 14.6 4 2 11 15 15 15 0 Apg6 coiled-coil region EphA2_TM PF14575.6 EGR29103.1 - 2.2 9.2 5.1 46 5.0 1.4 4.8 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain EF-hand_7 PF13499.6 EGR29104.1 - 1.4e-08 35.0 5.1 0.00042 20.7 1.1 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR29104.1 - 2.1e-05 23.7 4.9 0.00012 21.3 0.1 3.4 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 EGR29104.1 - 0.00019 21.1 4.5 0.00067 19.4 0.5 3.3 3 1 1 4 4 4 1 EF-hand domain EF-hand_8 PF13833.6 EGR29104.1 - 0.00057 19.7 1.9 0.053 13.4 0.1 2.7 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_9 PF14658.6 EGR29104.1 - 0.0029 17.9 0.0 1 9.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain Mst1_SARAH PF11629.8 EGR29104.1 - 0.2 11.8 2.4 1.1 9.4 0.7 2.8 3 0 0 3 3 3 0 C terminal SARAH domain of Mst1 Pkinase PF00069.25 EGR29105.1 - 2.4e-15 56.6 3.0 5.4e-15 55.5 3.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29105.1 - 5.7e-11 42.2 1.5 1.2e-10 41.1 1.5 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Consortin_C PF15281.6 EGR29105.1 - 0.65 10.0 2.9 0.6 10.1 0.3 2.3 2 0 0 2 2 2 0 Consortin C-terminus cNMP_binding PF00027.29 EGR29106.1 - 2.7e-29 101.1 0.0 4.7e-16 58.6 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain TMEM71 PF15121.6 EGR29106.1 - 0.022 14.4 0.0 0.091 12.4 0.0 2.0 2 0 0 2 2 2 0 TMEM71 protein family DUF2193 PF09959.9 EGR29106.1 - 0.037 12.5 0.0 0.065 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2193) PSS PF03034.15 EGR29107.1 - 2.4e-72 244.0 21.1 4.6e-71 239.8 21.1 2.0 1 1 0 1 1 1 1 Phosphatidyl serine synthase Vma12 PF11712.8 EGR29107.1 - 0.13 12.3 0.6 15 5.7 0.1 2.3 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4064 PF13273.6 EGR29107.1 - 6.2 7.2 7.7 5 7.4 0.1 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4064) Motile_Sperm PF00635.26 EGR29108.1 - 1.1e-19 70.3 0.1 1.1e-19 70.3 0.1 2.4 3 0 0 3 3 3 1 MSP (Major sperm protein) domain RIFIN PF02009.16 EGR29108.1 - 0.0023 17.9 7.3 0.0029 17.5 7.3 1.2 1 0 0 1 1 1 1 Rifin DUF3899 PF13038.6 EGR29108.1 - 6 7.4 7.1 0.82 10.2 0.6 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF3899) PMM PF03332.13 EGR29109.1 - 3.1e-92 308.3 8.7 3.5e-92 308.1 8.7 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EGR29109.1 - 3.2e-11 43.5 4.4 7.9e-11 42.2 4.3 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EGR29109.1 - 1.1e-05 25.2 0.0 0.015 14.9 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Trehalose_PPase PF02358.16 EGR29109.1 - 0.01 15.0 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 0 Trehalose-phosphatase HAD_2 PF13419.6 EGR29109.1 - 0.014 15.4 6.4 1.2 9.2 6.4 3.2 1 1 0 1 1 1 0 Haloacid dehalogenase-like hydrolase NitrOD1 PF18549.1 EGR29109.1 - 0.061 13.3 1.6 0.079 12.9 0.4 1.9 2 0 0 2 2 2 0 Nitrosopumilus output domain 1 Hydrolase_6 PF13344.6 EGR29109.1 - 0.089 12.9 0.1 0.19 11.8 0.1 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGR29109.1 - 0.14 12.5 0.0 0.22 11.8 0.0 1.5 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Peptidase_M16 PF00675.20 EGR29110.1 - 6.9e-33 113.7 0.3 6.9e-33 113.7 0.3 4.4 3 1 2 5 5 5 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 EGR29110.1 - 2.7e-18 66.3 18.6 2.7e-18 66.3 18.6 2.7 2 1 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 EGR29110.1 - 5e-14 52.7 22.8 3.3e-11 43.5 3.9 4.3 5 0 0 5 5 5 2 Peptidase M16 inactive domain DUF1327 PF07041.11 EGR29110.1 - 0.06 13.4 0.6 0.19 11.8 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1327) TerY_C PF15616.6 EGR29111.1 - 0.012 15.7 2.7 0.59 10.2 0.2 2.4 2 0 0 2 2 2 0 TerY-C metal binding domain HEAT PF02985.22 EGR29112.1 - 2e-10 40.0 2.9 0.061 13.6 0.0 8.2 10 0 0 10 10 10 3 HEAT repeat HEAT_EZ PF13513.6 EGR29112.1 - 9e-06 26.1 0.0 0.012 16.1 0.0 4.1 3 1 0 3 3 3 1 HEAT-like repeat IBN_N PF03810.19 EGR29112.1 - 0.003 17.4 2.6 0.003 17.4 2.6 4.9 5 0 0 5 5 5 1 Importin-beta N-terminal domain HEAT_2 PF13646.6 EGR29112.1 - 0.012 16.0 0.0 0.88 10.0 0.0 3.6 2 2 1 3 3 3 0 HEAT repeats DUF3685 PF12452.8 EGR29112.1 - 3.2 7.4 11.2 0.71 9.5 0.5 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3685) Polysacc_deac_1 PF01522.21 EGR29113.1 - 1.1e-12 48.0 0.0 1.6e-12 47.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide deacetylase DUF2812 PF11193.8 EGR29113.1 - 0.0071 16.5 0.1 0.015 15.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2812) Asp PF00026.23 EGR29114.1 - 1.8e-63 214.9 4.8 2.4e-63 214.5 4.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGR29114.1 - 7.7e-10 39.3 2.6 1.3e-06 28.7 0.1 2.5 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGR29114.1 - 0.022 15.4 0.0 2.8 8.7 0.0 3.7 3 1 0 3 3 3 0 Aspartyl protease Brix PF04427.18 EGR29115.1 - 1.2e-31 110.3 0.3 1.2e-31 110.3 0.3 1.6 2 0 0 2 2 2 1 Brix domain ubiquitin PF00240.23 EGR29116.1 - 0.0069 16.1 0.1 0.013 15.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Coilin_N PF15862.5 EGR29116.1 - 0.046 13.5 0.2 0.077 12.8 0.0 1.6 2 0 0 2 2 2 0 Coilin N-terminus Oxysterol_BP PF01237.18 EGR29117.1 - 5.4e-08 32.1 4.2 1.9e-06 27.0 0.2 2.2 1 1 1 2 2 2 2 Oxysterol-binding protein SNF2_N PF00176.23 EGR29118.1 - 9.7e-66 221.9 6.4 9.7e-66 221.9 6.4 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain DEAD PF00270.29 EGR29118.1 - 2e-05 24.4 0.1 6.3e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DEAD_2 PF06733.15 EGR29118.1 - 2.5e-05 24.0 1.0 2.5e-05 24.0 1.0 2.9 3 0 0 3 3 3 1 DEAD_2 DUF1798 PF08807.10 EGR29118.1 - 0.3 11.2 17.3 0.84 9.8 1.2 3.3 3 0 0 3 3 3 0 Bacterial domain of unknown function (DUF1798) SGL PF08450.12 EGR29119.1 - 0.00076 19.1 0.2 0.0072 15.9 0.1 2.5 2 1 0 2 2 2 1 SMP-30/Gluconolactonase/LRE-like region Lactonase PF10282.9 EGR29119.1 - 0.005 16.2 0.0 0.044 13.1 0.0 2.2 2 1 0 2 2 2 1 Lactonase, 7-bladed beta-propeller Arylesterase PF01731.20 EGR29119.1 - 0.019 15.1 0.2 0.17 12.1 0.1 2.7 2 0 0 2 2 2 0 Arylesterase Pkinase PF00069.25 EGR29120.1 - 1.9e-71 240.5 0.0 2.5e-71 240.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29120.1 - 9.7e-35 120.1 0.0 2e-34 119.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR29120.1 - 0.0037 16.6 0.0 0.0064 15.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGR29120.1 - 0.006 15.6 1.7 0.006 15.6 1.7 1.7 2 0 0 2 2 2 1 Haspin like kinase domain Methyltr_RsmB-F PF01189.17 EGR29121.1 - 2.1e-69 233.2 0.1 4.3e-69 232.2 0.1 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EGR29121.1 - 1.6e-10 41.4 0.0 1.2e-09 38.6 0.0 2.4 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF FtsJ PF01728.19 EGR29121.1 - 5.2e-05 23.4 0.0 9.7e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF2431 PF10354.9 EGR29121.1 - 0.0037 17.5 0.0 0.0096 16.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF2431) BUD22 PF09073.10 EGR29121.1 - 0.011 15.1 21.0 0.013 14.9 21.0 1.2 1 0 0 1 1 1 0 BUD22 Merozoite_SPAM PF07133.11 EGR29121.1 - 0.41 10.6 49.0 1 9.3 49.0 1.6 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.14 EGR29121.1 - 0.77 8.0 29.0 1.2 7.3 29.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EGR29121.1 - 2.3 6.9 19.5 3 6.5 19.5 1.2 1 0 0 1 1 1 0 Presenilin DUF2370 PF10176.9 EGR29121.1 - 2.3 7.8 6.5 4.5 6.9 6.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) SDA1 PF05285.12 EGR29121.1 - 4.1 6.7 36.2 7 6.0 36.2 1.3 1 0 0 1 1 1 0 SDA1 Zip PF02535.22 EGR29121.1 - 8.7 5.5 14.8 13 4.9 14.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter VSP PF03302.13 EGR29122.1 - 2.2e-14 53.2 212.4 4.5e-05 22.5 16.1 8.7 2 1 6 8 8 8 5 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EGR29122.1 - 5.6e-10 39.3 263.8 4.8e-05 23.5 15.5 15.7 2 2 12 14 14 14 8 Furin-like repeat, cysteine-rich GF_recep_IV PF14843.6 EGR29122.1 - 0.64 9.8 252.0 0.014 15.2 22.0 10.6 1 1 6 8 8 8 0 Growth factor receptor domain IV GTP_EFTU PF00009.27 EGR29123.1 - 6.2e-32 110.7 0.2 1.3e-31 109.6 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGR29123.1 - 3e-07 30.5 0.1 8.4e-07 29.1 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGR29123.1 - 0.00026 20.5 2.9 0.0011 18.4 2.9 2.0 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.25 EGR29123.1 - 0.0035 17.7 0.0 0.0087 16.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 ATP_bind_1 PF03029.17 EGR29123.1 - 0.0076 16.1 2.3 1.7 8.4 0.7 3.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.9 EGR29123.1 - 0.056 13.2 2.7 3.4 7.4 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EGR29123.1 - 0.35 10.8 6.1 0.19 11.6 2.0 2.3 1 1 1 2 2 2 0 RsgA GTPase Pkinase PF00069.25 EGR29124.1 - 3.7e-69 233.0 3.4 6e-69 232.3 3.4 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29124.1 - 8.7e-47 159.6 1.3 1.2e-46 159.1 1.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29124.1 - 7.6e-11 41.9 0.5 1.5e-10 40.9 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR29124.1 - 0.00028 19.8 1.0 0.0004 19.3 0.0 1.8 3 0 0 3 3 3 1 Fungal protein kinase SAS4 PF15460.6 EGR29124.1 - 0.34 11.0 7.1 0.23 11.6 2.6 2.4 2 1 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 DUF3126 PF11324.8 EGR29124.1 - 2.2 8.2 6.8 20 5.1 3.1 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3126) Pkinase PF00069.25 EGR29125.1 - 1.2e-82 277.3 1.0 1.9e-82 276.6 1.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29125.1 - 3.6e-42 144.4 0.1 5.8e-42 143.8 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 EGR29125.1 - 1.1e-22 77.8 13.3 5e-06 25.7 0.3 5.1 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 EGR29125.1 - 1.4e-21 76.7 7.5 5e-10 39.7 0.1 3.9 2 1 2 4 4 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EGR29125.1 - 1.4e-18 65.2 10.8 3.4e-05 23.4 0.1 5.1 5 0 0 5 5 4 4 EF-hand domain EF-hand_5 PF13202.6 EGR29125.1 - 2e-18 65.0 5.7 0.00019 20.8 0.1 5.1 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGR29125.1 - 1.7e-14 53.4 11.5 2.1e-05 24.3 0.4 5.2 3 1 2 5 5 5 4 EF-hand domain pair Kinase-like PF14531.6 EGR29125.1 - 2.1e-10 40.4 0.0 1.6e-08 34.2 0.0 2.3 1 1 1 2 2 2 1 Kinase-like SPARC_Ca_bdg PF10591.9 EGR29125.1 - 8.2e-10 39.0 6.2 3.6e-05 24.1 0.4 2.8 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.14 EGR29125.1 - 1.7e-06 27.5 0.2 5.2e-06 26.0 0.2 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR29125.1 - 3.7e-05 22.7 0.2 9.2e-05 21.4 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase EF-hand_4 PF12763.7 EGR29125.1 - 5.1e-05 23.2 2.4 0.0033 17.4 0.1 2.9 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand APH PF01636.23 EGR29125.1 - 0.00028 20.9 0.0 0.00041 20.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EGR29125.1 - 0.0016 18.0 0.6 0.0061 16.1 0.1 2.2 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL RIO1 PF01163.22 EGR29125.1 - 0.0052 16.4 0.5 0.013 15.1 0.5 1.6 1 0 0 1 1 1 1 RIO1 family Dockerin_1 PF00404.18 EGR29125.1 - 0.018 15.2 0.6 13 6.0 0.1 3.8 2 1 1 3 3 3 0 Dockerin type I domain 7TMR-HDED PF07697.11 EGR29125.1 - 0.021 15.0 2.1 0.69 10.0 0.1 2.7 1 1 1 2 2 2 0 7TM-HD extracellular Clathrin_lg_ch PF01086.17 EGR29126.1 - 0.012 15.7 1.3 0.021 14.9 1.3 1.3 1 0 0 1 1 1 0 Clathrin light chain tRNA-synt_2c PF01411.19 EGR29127.1 - 3.5e-63 214.0 0.0 1.9e-62 211.5 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EGR29127.1 - 1.9e-13 50.3 0.5 1.1e-12 47.8 0.3 2.4 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain AMP-binding PF00501.28 EGR29128.1 - 4.2e-73 246.4 0.0 5.2e-73 246.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGR29128.1 - 7.3e-19 68.5 0.3 1.4e-18 67.6 0.3 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGR29128.1 - 2.2e-14 53.1 3.0 4.6e-14 52.1 3.0 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding PF00501.28 EGR29129.1 - 2e-67 227.7 0.0 3e-67 227.1 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGR29129.1 - 0.00031 21.6 0.0 0.00069 20.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF4606 PF15379.6 EGR29130.1 - 0.11 12.7 6.4 0.21 11.8 6.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) DUF3095 PF11294.8 EGR29131.1 - 3.2 6.7 7.1 0.3 10.1 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3095) PI3_PI4_kinase PF00454.27 EGR29132.1 - 4.4e-34 118.4 1.2 8.1e-34 117.6 1.2 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 EGR29132.1 - 0.22 12.0 3.8 0.36 11.3 0.4 2.6 2 1 0 2 2 2 0 FKBP12-rapamycin binding domain SHIPPO-rpt PF07004.12 EGR29133.1 - 4.5e-07 30.5 9.7 0.071 14.1 0.2 5.3 5 0 0 5 5 5 4 Sperm-tail PG-rich repeat Pkinase PF00069.25 EGR29134.1 - 7.1e-34 117.4 0.0 7.8e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29134.1 - 2.5e-15 56.5 0.0 2.7e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR29134.1 - 0.00071 18.5 0.0 0.0008 18.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGR29134.1 - 0.0084 15.1 0.0 0.01 14.8 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Inhibitor_Mig-6 PF11555.8 EGR29134.1 - 0.012 15.7 0.0 0.016 15.3 0.0 1.2 1 0 0 1 1 1 0 EGFR receptor inhibitor Mig-6 Kinase-like PF14531.6 EGR29134.1 - 0.021 14.2 0.0 0.027 13.8 0.0 1.2 1 0 0 1 1 1 0 Kinase-like ParcG PF10274.9 EGR29135.1 - 1.9e-13 51.0 0.0 2.1e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein MFS_1 PF07690.16 EGR29136.1 - 1.2e-08 34.3 39.1 8.3e-06 25.0 12.7 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily DctQ PF04290.12 EGR29137.1 - 0.11 12.4 0.1 0.15 12.0 0.1 1.1 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component Hist_deacetyl PF00850.19 EGR29138.1 - 1.3e-84 284.3 0.0 2e-84 283.7 0.0 1.3 1 0 0 1 1 1 1 Histone deacetylase domain IPK PF03770.16 EGR29138.1 - 1.1e-24 87.4 13.1 1.3e-24 87.1 7.5 2.7 2 1 0 2 2 2 1 Inositol polyphosphate kinase Pkinase PF00069.25 EGR29139.1 - 7.3e-65 219.0 0.2 9.8e-65 218.5 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29139.1 - 2.4e-46 158.1 0.1 3.3e-46 157.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EGR29139.1 - 0.00011 21.9 0.7 0.008 15.8 0.7 2.4 1 1 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EGR29139.1 - 0.0002 20.3 0.0 0.00035 19.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR29139.1 - 0.0016 17.9 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGR29139.1 - 0.0016 17.8 0.1 0.01 15.2 0.0 2.2 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 EGR29139.1 - 0.0019 18.1 0.0 0.0027 17.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3644 PF12358.8 EGR29139.1 - 0.31 11.5 3.6 0.31 11.6 0.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3644) His_Phos_1 PF00300.22 EGR29140.1 - 4.1e-14 52.7 0.0 2.2e-11 43.8 0.0 2.8 1 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) ABC2_membrane_3 PF12698.7 EGR29140.1 - 0.04 13.0 0.2 0.041 13.0 0.2 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein zf-B_box PF00643.24 EGR29141.1 - 1.5e-07 31.4 7.7 1.5e-07 31.4 7.7 2.2 2 0 0 2 2 2 1 B-box zinc finger FliD_N PF02465.18 EGR29141.1 - 0.061 14.0 0.0 0.061 14.0 0.0 3.6 4 0 0 4 4 4 0 Flagellar hook-associated protein 2 N-terminus Zip PF02535.22 EGR29141.1 - 5.9 6.0 5.9 6.8 5.8 5.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MFS_1 PF07690.16 EGR29142.1 - 3.6e-10 39.3 36.5 1.9e-05 23.7 13.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Fig1 PF12351.8 EGR29142.1 - 1 9.3 6.9 0.29 11.0 0.3 2.8 3 1 0 3 3 3 0 Ca2+ regulator and membrane fusion protein Fig1 MFS_2 PF13347.6 EGR29142.1 - 2.7 6.4 30.6 0.12 10.9 7.6 3.3 3 1 0 3 3 3 0 MFS/sugar transport protein Pkinase PF00069.25 EGR29143.1 - 3e-61 207.1 0.4 3e-61 207.1 0.4 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29143.1 - 3.9e-42 144.3 0.0 3.9e-42 144.3 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29143.1 - 8.5e-08 31.8 4.8 5.6e-05 22.6 0.0 2.9 2 1 1 3 3 3 2 Kinase-like APH PF01636.23 EGR29143.1 - 0.017 15.1 0.0 0.032 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family NAD_Gly3P_dh_N PF01210.23 EGR29143.1 - 0.42 10.6 0.0 0.42 10.6 0.0 2.8 1 1 2 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Presenilin PF01080.17 EGR29143.1 - 3.2 6.4 16.1 4.7 5.9 16.1 1.2 1 0 0 1 1 1 0 Presenilin GvpL_GvpF PF06386.11 EGR29143.1 - 7.3 6.4 7.1 11 5.9 7.1 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Exonuc_VII_L PF02601.15 EGR29143.1 - 7.7 6.0 17.9 11 5.4 17.9 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2769 PF10967.8 EGR29144.1 - 0.11 13.1 8.9 0.56 10.9 8.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2769) Chlam_PMP PF02415.17 EGR29144.1 - 0.26 11.8 2.5 1.3 9.6 0.0 3.0 3 0 0 3 3 3 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat DRMBL PF07522.14 EGR29145.1 - 3.5e-06 27.1 0.0 1.8e-05 24.9 0.0 2.3 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EGR29145.1 - 0.0061 16.1 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGR29145.1 - 0.029 14.4 0.1 1.8 8.6 0.1 2.1 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily Kinetochor_Ybp2 PF08568.10 EGR29146.1 - 0.03 12.8 3.0 0.045 12.2 3.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family, YAP/Alf4/glomulin Pkinase PF00069.25 EGR29147.1 - 5.8e-29 101.3 0.0 5.8e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29147.1 - 2.7e-10 40.0 0.0 3.2e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR29147.1 - 0.23 11.3 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 EGR29148.1 - 1.9e-55 188.1 0.5 1.9e-55 188.1 0.5 2.4 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29148.1 - 3.8e-27 95.2 1.6 8e-27 94.1 0.2 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EGR29148.1 - 1.6e-10 41.3 0.2 2e-08 34.6 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGR29148.1 - 1.3e-09 36.9 0.3 4.6e-08 32.1 0.1 2.8 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EGR29148.1 - 4.6e-08 32.8 0.0 1.4e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair Kdo PF06293.14 EGR29148.1 - 5e-06 26.0 0.1 1.1e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_6 PF13405.6 EGR29148.1 - 6.4e-06 25.7 0.3 0.0068 16.2 0.0 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 EGR29148.1 - 2.1e-05 23.8 0.1 8.8e-05 21.8 0.1 2.2 1 0 0 1 1 1 1 EF hand Pkinase_fungal PF17667.1 EGR29148.1 - 0.0002 20.3 0.0 0.00038 19.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR29148.1 - 0.0038 17.2 0.0 0.0069 16.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGR29148.1 - 0.031 13.9 0.8 0.056 13.0 0.1 1.8 2 0 0 2 2 2 0 RIO1 family EF-hand_9 PF14658.6 EGR29148.1 - 0.14 12.5 0.0 0.47 10.8 0.0 1.9 2 0 0 2 2 2 0 EF-hand domain Acetyltransf_3 PF13302.7 EGR29149.1 - 2.9e-20 73.4 0.0 3.8e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGR29149.1 - 2.4e-07 31.0 0.0 3.6e-07 30.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EGR29149.1 - 7.5e-07 28.9 0.1 1.3e-06 28.2 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGR29149.1 - 1.5e-06 28.1 0.0 2.3e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EGR29149.1 - 0.00015 21.9 2.1 0.00015 21.9 2.1 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGR29149.1 - 0.00059 19.8 1.8 0.0012 18.8 1.8 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGR29149.1 - 0.0015 18.9 0.1 0.0039 17.6 0.1 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 EGR29149.1 - 0.0057 16.3 0.1 0.014 15.0 0.0 1.7 1 1 1 2 2 2 1 GNAT acetyltransferase Acetyltransf_CG PF14542.6 EGR29149.1 - 0.065 13.4 0.5 5.6 7.2 0.0 2.8 3 0 0 3 3 3 0 GCN5-related N-acetyl-transferase Osmo_CC PF08946.10 EGR29149.1 - 0.14 12.5 0.5 0.14 12.5 0.5 2.5 3 0 0 3 3 3 0 Osmosensory transporter coiled coil CDP-OH_P_transf PF01066.21 EGR29150.1 - 3e-12 47.1 1.0 7.8e-12 45.8 0.0 2.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase RRM_1 PF00076.22 EGR29151.1 - 8.7e-17 60.7 0.1 2.1e-16 59.5 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 EGR29151.1 - 3.7e-10 40.3 2.4 3.7e-10 40.3 2.4 5.2 4 1 1 5 5 5 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal CDC27 PF09507.10 EGR29151.1 - 0.46 9.8 33.9 0.66 9.3 25.0 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 HEAT PF02985.22 EGR29152.1 - 1.5e-21 74.6 1.8 0.087 13.1 0.0 11.9 13 0 0 13 13 13 4 HEAT repeat HEAT_2 PF13646.6 EGR29152.1 - 6.3e-10 39.3 0.0 0.86 10.0 0.0 6.6 4 2 3 7 7 7 4 HEAT repeats Cnd1 PF12717.7 EGR29152.1 - 2.2e-05 24.6 25.5 0.00032 20.8 0.5 5.3 2 1 3 6 6 6 3 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EGR29152.1 - 0.0016 18.9 0.5 4.8 7.8 0.0 5.4 7 0 0 7 7 7 1 HEAT-like repeat CIF PF16374.5 EGR29152.1 - 0.067 13.3 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Cycle inhibiting factor (CIF) Trp_Tyr_perm PF03222.13 EGR29152.1 - 0.094 11.7 0.4 0.14 11.1 0.4 1.2 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family Kelch_4 PF13418.6 EGR29153.1 - 6.4e-32 109.3 2.1 5.4e-06 26.3 0.0 6.2 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 EGR29153.1 - 1.8e-24 85.2 0.1 0.00012 22.0 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 EGR29153.1 - 4.8e-23 80.9 2.3 2.7e-06 27.5 0.0 6.1 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EGR29153.1 - 3.2e-16 59.0 7.1 0.00059 20.0 0.0 6.7 6 1 1 7 7 7 4 Kelch motif Kelch_1 PF01344.25 EGR29153.1 - 3.3e-12 45.8 0.1 0.014 15.0 0.0 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 EGR29153.1 - 2.2e-09 36.9 4.6 0.24 11.5 0.2 6.4 6 1 0 6 6 6 3 Kelch motif RAG2 PF03089.14 EGR29153.1 - 0.0092 15.0 0.0 0.14 11.1 0.0 2.5 2 1 0 2 2 2 1 Recombination activating protein 2 ECH_2 PF16113.5 EGR29154.1 - 8.5e-50 170.1 16.4 1.6e-30 106.8 0.0 4.8 5 1 0 5 5 5 2 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EGR29154.1 - 1.9e-10 40.5 0.5 6.2e-10 38.8 0.0 2.2 3 0 0 3 3 3 1 Enoyl-CoA hydratase/isomerase NCD3G PF07562.14 EGR29156.1 - 1.2 9.1 11.9 0.36 10.8 3.0 2.9 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR TadE PF07811.12 EGR29156.1 - 1.9 8.8 9.7 4.8 7.5 0.6 2.9 3 0 0 3 3 3 0 TadE-like protein FSIP1 PF15554.6 EGR29157.1 - 0.053 12.6 9.5 0.06 12.4 9.5 1.1 1 0 0 1 1 1 0 FSIP1 family Collagen PF01391.18 EGR29158.1 - 1.8e-07 30.8 4.3 2.2e-07 30.5 4.3 1.1 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) Peptidase_M8 PF01457.16 EGR29161.1 - 7.5e-32 110.7 6.6 6.3e-29 101.1 6.6 2.1 1 1 0 1 1 1 1 Leishmanolysin EGF_2 PF07974.13 EGR29161.1 - 0.0003 21.1 9.7 0.0003 21.1 9.7 3.9 3 1 1 4 4 4 1 EGF-like domain EGF_Tenascin PF18720.1 EGR29161.1 - 0.0021 18.1 6.5 0.0078 16.2 6.5 2.1 1 0 0 1 1 1 1 Tenascin EGF domain DUF3810 PF12725.7 EGR29161.1 - 0.046 13.1 0.1 0.087 12.1 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Peptidase_M8 PF01457.16 EGR29162.1 - 1.2e-31 110.0 0.0 1.8e-31 109.5 0.0 1.2 1 0 0 1 1 1 1 Leishmanolysin Mic1 PF07035.12 EGR29162.1 - 0.066 12.9 0.0 0.22 11.2 0.0 1.7 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like Zincin_1 PF06262.11 EGR29162.1 - 0.081 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase Peptidase_M90 PF06167.12 EGR29162.1 - 0.14 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 EGF_2 PF07974.13 EGR29163.1 - 2.4e-05 24.6 14.9 2.4e-05 24.6 14.9 3.2 3 1 0 3 3 3 1 EGF-like domain EGF_Tenascin PF18720.1 EGR29163.1 - 2.7e-05 24.1 7.2 6.9e-05 22.8 7.2 1.8 1 0 0 1 1 1 1 Tenascin EGF domain Aegerolysin PF06355.13 EGR29163.1 - 0.079 13.0 0.1 0.097 12.7 0.1 1.1 1 0 0 1 1 1 0 Aegerolysin Toxin_2 PF00451.19 EGR29163.1 - 0.18 12.1 15.2 0.95 9.8 10.2 2.9 2 0 0 2 2 2 0 Scorpion short toxin, BmKK2 EB PF01683.18 EGR29163.1 - 1.2 9.5 17.0 5 7.5 17.0 2.0 1 1 0 1 1 1 0 EB module ABC_tran PF00005.27 EGR29164.1 - 1.1e-41 142.6 3.8 1.4e-24 87.1 0.3 3.6 4 0 0 4 4 3 2 ABC transporter ABC_membrane PF00664.23 EGR29164.1 - 1.3e-20 74.2 26.9 3e-20 73.0 26.7 1.7 1 1 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EGR29164.1 - 4.6e-10 39.3 30.9 1.5e-05 24.6 3.8 4.9 2 2 2 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGR29164.1 - 2.1e-09 37.8 0.1 0.00094 19.5 0.0 3.0 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGR29164.1 - 1.1e-08 35.2 1.7 0.00064 19.7 0.2 2.8 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 EGR29164.1 - 2.4e-08 33.4 0.4 0.0027 16.8 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_7 PF12775.7 EGR29164.1 - 3.8e-08 33.1 2.7 0.0026 17.3 0.4 2.8 2 0 0 2 2 2 2 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EGR29164.1 - 3.4e-07 30.3 2.5 0.0084 16.2 0.6 3.4 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 EGR29164.1 - 7.3e-07 29.7 0.0 0.06 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 EGR29164.1 - 8.2e-07 28.7 0.2 0.024 14.3 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA PF00004.29 EGR29164.1 - 1.2e-05 25.8 6.1 0.022 15.2 0.2 3.8 4 1 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EGR29164.1 - 4.7e-05 23.8 0.3 0.078 13.3 0.0 3.0 2 2 0 2 2 2 1 AAA domain NB-ARC PF00931.22 EGR29164.1 - 8.8e-05 21.8 0.5 0.035 13.3 0.0 3.1 2 2 0 2 2 2 1 NB-ARC domain cobW PF02492.19 EGR29164.1 - 9.6e-05 22.0 0.4 0.14 11.8 0.1 2.9 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain ATP-synt_ab PF00006.25 EGR29164.1 - 0.00011 22.0 0.0 0.28 10.8 0.0 2.5 2 1 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain DUF815 PF05673.13 EGR29164.1 - 0.00022 20.5 0.5 0.17 11.1 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.12 EGR29164.1 - 0.00035 20.5 0.0 0.076 12.9 0.0 2.8 2 0 0 2 2 2 1 NACHT domain Roc PF08477.13 EGR29164.1 - 0.00039 20.6 0.3 1.5 9.1 0.1 3.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_30 PF13604.6 EGR29164.1 - 0.00051 19.8 0.0 0.47 10.1 0.0 2.9 3 1 0 3 3 2 1 AAA domain FtsK_SpoIIIE PF01580.18 EGR29164.1 - 0.00059 19.3 4.2 0.032 13.6 0.0 2.8 3 0 0 3 3 3 1 FtsK/SpoIIIE family AAA_24 PF13479.6 EGR29164.1 - 0.00065 19.5 0.1 0.57 9.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EGR29164.1 - 0.0011 18.3 0.0 0.18 11.0 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin MobB PF03205.14 EGR29164.1 - 0.0013 18.6 0.2 0.33 10.8 0.0 2.8 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.6 EGR29164.1 - 0.0022 18.1 0.0 2.4 8.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 EGR29164.1 - 0.0038 17.6 3.1 1.5 9.2 0.1 4.0 4 0 0 4 4 2 1 RNA helicase PduV-EutP PF10662.9 EGR29164.1 - 0.0045 16.8 1.9 0.54 10.0 0.2 3.0 3 0 0 3 3 2 1 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 EGR29164.1 - 0.013 15.5 0.0 5.9 6.9 0.0 2.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DEAD PF00270.29 EGR29164.1 - 0.013 15.2 3.0 0.32 10.7 1.3 3.2 3 1 0 3 3 3 0 DEAD/DEAH box helicase Dynamin_N PF00350.23 EGR29164.1 - 0.014 15.5 0.6 0.014 15.5 0.6 4.6 4 1 0 4 4 3 0 Dynamin family TrwB_AAD_bind PF10412.9 EGR29164.1 - 0.016 14.2 0.2 3.6 6.4 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_5 PF07728.14 EGR29164.1 - 0.02 14.9 0.1 4.9 7.1 0.1 3.3 3 1 0 3 3 2 0 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EGR29164.1 - 0.024 14.4 0.8 2.2 8.0 0.0 3.2 3 0 0 3 3 3 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGR29164.1 - 0.028 13.8 0.1 2.4 7.5 0.0 2.9 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_21 PF13304.6 EGR29164.1 - 0.033 14.0 23.7 0.095 12.5 0.9 5.7 4 2 2 6 6 5 0 AAA domain, putative AbiEii toxin, Type IV TA system PRK PF00485.18 EGR29164.1 - 0.035 13.8 2.5 0.92 9.2 0.0 3.0 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family SbcCD_C PF13558.6 EGR29164.1 - 0.19 12.0 0.2 8.5 6.7 0.0 3.2 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 EGR29164.1 - 0.21 11.8 0.1 13 6.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain YafQ_toxin PF15738.5 EGR29164.1 - 0.34 11.2 3.3 0.21 11.9 0.2 2.2 2 0 0 2 2 1 0 Bacterial toxin of type II toxin-antitoxin system, YafQ AAA_18 PF13238.6 EGR29164.1 - 0.95 10.0 14.7 0.7 10.4 1.2 5.0 4 2 1 5 5 5 0 AAA domain AAA_11 PF13086.6 EGR29164.1 - 0.97 9.2 12.7 8 6.2 0.1 3.9 3 2 1 4 4 4 0 AAA domain Pkinase PF00069.25 EGR29165.1 - 0.00057 19.3 0.3 0.00057 19.3 0.3 1.5 1 1 0 1 1 1 1 Protein kinase domain Lipin_mid PF16876.5 EGR29165.1 - 0.012 15.8 0.6 0.016 15.3 0.6 1.2 1 0 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain FKS1_dom1 PF14288.6 EGR29165.1 - 0.022 15.1 1.7 0.025 14.9 1.7 1.0 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Bac_small_YrzI PF09501.10 EGR29165.1 - 5.7 7.2 8.1 17 5.6 5.4 2.5 2 1 0 2 2 2 0 Probable sporulation protein (Bac_small_yrzI) EF-hand_6 PF13405.6 EGR29166.1 - 2.4e-17 61.3 16.4 0.0017 18.1 0.1 8.5 7 0 0 7 7 7 4 EF-hand domain EF-hand_7 PF13499.6 EGR29166.1 - 2.4e-13 50.3 27.5 0.017 15.6 0.5 7.8 7 0 0 7 7 7 4 EF-hand domain pair EF-hand_8 PF13833.6 EGR29166.1 - 7.1e-08 32.2 1.5 0.0013 18.5 0.0 6.3 7 0 0 7 7 7 1 EF-hand domain pair EF-hand_11 PF08976.11 EGR29166.1 - 7.3e-08 33.2 25.6 0.18 12.7 0.1 8.1 8 0 0 8 8 8 3 EF-hand domain EF-hand_1 PF00036.32 EGR29166.1 - 1.3e-07 30.7 11.6 0.048 13.2 0.0 6.6 7 0 0 7 7 7 2 EF hand FGAR-AT_linker PF18072.1 EGR29166.1 - 0.01 16.3 7.1 4.1 8.0 0.0 5.8 8 0 0 8 8 8 0 Formylglycinamide ribonucleotide amidotransferase linker domain RseA_C PF03873.13 EGR29166.1 - 0.048 13.9 0.2 22 5.4 0.0 3.5 3 0 0 3 3 3 0 Anti sigma-E protein RseA, C-terminal domain Pkinase PF00069.25 EGR29167.1 - 8e-71 238.5 0.3 9.9e-71 238.2 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29167.1 - 5e-37 127.6 0.0 6.9e-37 127.1 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR29167.1 - 5.9e-07 29.0 0.1 9.4e-07 28.4 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGR29167.1 - 0.00015 20.9 1.0 0.00015 20.9 1.0 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EGR29167.1 - 0.032 13.6 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Kinase-like HECT PF00632.25 EGR29168.1 - 8.4e-45 153.6 1.7 1e-44 153.3 1.7 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Recep_L_domain PF01030.24 EGR29168.1 - 0.0053 16.9 3.2 0.0065 16.6 2.1 1.7 1 1 0 1 1 1 1 Receptor L domain Sigma54_activ_2 PF14532.6 EGR29168.1 - 0.0061 16.7 0.1 0.01 16.0 0.1 1.4 1 0 0 1 1 1 1 Sigma-54 interaction domain Peptidase_M8 PF01457.16 EGR29169.1 - 5.7e-24 84.7 0.2 6.8e-24 84.4 0.2 1.2 1 0 0 1 1 1 1 Leishmanolysin EGF_2 PF07974.13 EGR29169.1 - 0.035 14.5 9.9 0.035 14.5 9.9 2.8 2 1 1 3 3 3 0 EGF-like domain Peptidase_M8 PF01457.16 EGR29170.1 - 4e-40 138.0 3.1 3.2e-34 118.5 0.0 2.1 1 1 1 2 2 2 2 Leishmanolysin EGF_2 PF07974.13 EGR29170.1 - 0.0014 18.9 12.3 0.0014 18.9 12.3 3.6 3 1 0 3 3 3 1 EGF-like domain BSP PF04450.12 EGR29170.1 - 0.088 12.6 0.0 2.8 7.7 0.0 2.2 2 0 0 2 2 2 0 Peptidase of plants and bacteria Peptidase_M10 PF00413.24 EGR29170.1 - 0.12 12.2 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Matrixin EGF_Tenascin PF18720.1 EGR29170.1 - 1.1 9.3 10.7 0.2 11.8 5.7 2.5 2 0 0 2 2 2 0 Tenascin EGF domain Adap_comp_sub PF00928.21 EGR29171.1 - 1e-30 107.0 9.8 1.8e-30 106.2 9.8 1.4 1 0 0 1 1 1 1 Adaptor complexes medium subunit family eIF-3_zeta PF05091.12 EGR29172.1 - 1.9e-104 350.5 22.8 1.7e-95 321.0 19.4 2.0 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pkinase PF00069.25 EGR29173.1 - 2.8e-10 40.0 1.4 8e-10 38.5 0.1 2.0 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29173.1 - 0.0038 16.5 0.1 0.0057 16.0 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1456 PF07308.13 EGR29173.1 - 0.0058 16.9 0.1 0.015 15.6 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1456) EF-hand_1 PF00036.32 EGR29173.1 - 0.042 13.4 0.1 0.042 13.4 0.1 3.2 4 0 0 4 4 4 0 EF hand EF-hand_6 PF13405.6 EGR29173.1 - 0.18 11.8 5.8 0.81 9.8 0.1 3.7 3 2 1 4 4 4 0 EF-hand domain Prosystemin PF07376.11 EGR29173.1 - 0.27 10.7 5.0 0.37 10.2 3.5 1.7 1 1 1 2 2 2 0 Prosystemin EF-hand_7 PF13499.6 EGR29173.1 - 0.3 11.5 5.3 4.8 7.7 0.2 2.9 2 2 0 2 2 2 0 EF-hand domain pair Pkinase PF00069.25 EGR29174.1 - 1.1e-20 74.1 0.7 3e-20 72.7 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29174.1 - 1.7e-11 43.9 0.2 5.8e-11 42.2 0.0 1.8 2 1 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29174.1 - 0.0013 18.1 0.0 0.0022 17.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PTS_2-RNA PF01885.16 EGR29175.1 - 1.4e-62 211.0 0.9 1.7e-62 210.7 0.9 1.1 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family H_PPase PF03030.16 EGR29176.1 - 8.8e-245 814.3 20.4 1.1e-244 814.0 20.4 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Pox_A14 PF05767.12 EGR29176.1 - 0.018 15.2 3.3 0.051 13.7 0.7 3.1 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 DUF3810 PF12725.7 EGR29176.1 - 0.91 8.8 4.2 0.32 10.3 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) Orf78 PF06024.12 EGR29176.1 - 1 9.7 3.3 8.4 6.8 0.1 3.3 4 0 0 4 4 4 0 Orf78 (ac78) cNMP_binding PF00027.29 EGR29177.1 - 7.6e-44 147.7 0.0 1.8e-21 76.0 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain ASH PF15780.5 EGR29178.1 - 1.1e-37 128.2 40.5 0.0006 20.0 0.0 17.5 18 0 0 18 18 18 8 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 EGR29178.1 - 6.8e-08 32.3 39.1 0.076 12.9 1.1 11.6 12 0 0 12 12 12 3 MSP (Major sperm protein) domain DUF1573 PF07610.11 EGR29178.1 - 0.0026 17.7 22.2 0.39 10.8 0.1 9.0 8 0 0 8 8 8 2 Protein of unknown function (DUF1573) AAA_28 PF13521.6 EGR29178.1 - 0.016 15.5 0.0 0.041 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGR29178.1 - 0.024 15.2 0.1 0.024 15.2 0.1 2.7 3 0 0 3 3 3 0 AAA domain MCM PF00493.23 EGR29178.1 - 0.032 13.3 0.3 0.085 11.9 0.3 1.6 1 0 0 1 1 1 0 MCM P-loop domain ADK PF00406.22 EGR29178.1 - 0.097 12.8 0.8 1.6 8.8 0.0 2.7 2 0 0 2 2 2 0 Adenylate kinase TMEM131_like PF12371.8 EGR29178.1 - 0.18 12.1 0.0 0.18 12.1 0.0 9.6 11 0 0 11 11 11 0 Transmembrane protein 131-like Hydin_ADK PF17213.3 EGR29178.1 - 0.41 10.9 13.6 0.55 10.5 0.0 4.1 3 1 0 4 4 4 0 Hydin Adenylate kinase-like domain ASH PF15780.5 EGR29179.1 - 2e-21 76.0 4.3 0.0067 16.6 0.0 10.7 12 0 0 12 12 12 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 EGR29179.1 - 3.5e-18 65.6 0.0 0.0026 17.9 0.0 7.3 9 0 0 9 9 9 4 Flagellar-associated PapD-like Motile_Sperm PF00635.26 EGR29179.1 - 1.2e-09 38.0 18.6 0.037 13.9 0.0 9.5 11 1 0 11 11 11 2 MSP (Major sperm protein) domain DUF1573 PF07610.11 EGR29179.1 - 1.6e-06 28.0 22.3 0.47 10.5 0.0 11.3 13 1 0 13 13 13 3 Protein of unknown function (DUF1573) MYCBPAP PF14646.6 EGR29179.1 - 2.9e-05 23.2 23.1 0.0034 16.4 0.3 6.3 6 1 0 7 7 7 4 MYCBP-associated protein family TMEM131_like PF12371.8 EGR29179.1 - 0.046 14.0 16.4 9.4 6.6 0.1 8.2 8 0 0 8 8 8 0 Transmembrane protein 131-like ATP-gua_Ptrans PF00217.19 EGR29180.1 - 1.6e-35 122.5 0.6 4.2e-35 121.2 0.2 1.9 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, C-terminal catalytic domain ATP-gua_PtransN PF02807.15 EGR29180.1 - 2.1e-14 53.7 0.1 1.2e-13 51.2 0.0 2.3 2 0 0 2 2 2 1 ATP:guanido phosphotransferase, N-terminal domain FAM165 PF14981.6 EGR29180.1 - 0.0089 15.8 0.3 0.047 13.5 0.0 2.3 2 0 0 2 2 2 1 FAM165 family HHH_9 PF17674.1 EGR29180.1 - 0.094 13.6 1.5 0.56 11.1 0.0 2.8 2 1 1 3 3 3 0 HHH domain Glutaminase PF04960.15 EGR29182.1 - 2.2e-94 315.8 0.1 2.8e-94 315.5 0.1 1.1 1 0 0 1 1 1 1 Glutaminase Ank_5 PF13857.6 EGR29182.1 - 0.00057 20.1 0.0 0.0015 18.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGR29182.1 - 0.0032 18.0 0.0 0.04 14.5 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGR29182.1 - 0.0071 16.9 0.0 0.022 15.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGR29182.1 - 0.0079 16.6 0.1 0.059 13.8 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat DUF3929 PF13066.6 EGR29182.1 - 0.048 13.7 0.0 0.16 12.0 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3929) Ank_3 PF13606.6 EGR29182.1 - 0.072 13.7 0.1 0.58 10.9 0.0 2.6 3 0 0 3 3 3 0 Ankyrin repeat TPR_12 PF13424.6 EGR29183.1 - 1.6e-32 111.6 2.4 6.2e-13 48.9 0.3 5.1 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGR29183.1 - 3e-18 64.4 4.5 0.002 18.1 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGR29183.1 - 4.1e-15 54.9 11.6 0.00048 19.8 0.0 5.7 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGR29183.1 - 2.1e-09 37.0 2.4 0.08 12.8 0.0 5.9 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGR29183.1 - 2e-08 33.8 24.8 0.0069 16.5 0.3 7.0 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGR29183.1 - 2.5e-06 27.1 6.9 0.0046 16.9 0.1 5.3 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGR29183.1 - 5.1e-05 22.8 0.1 7.3e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 MalT-like TPR region TPR_19 PF14559.6 EGR29183.1 - 7.7e-05 23.1 4.4 0.94 10.0 0.0 4.5 3 3 2 5 5 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGR29183.1 - 0.00013 22.0 2.1 0.0062 16.6 0.3 3.7 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.20 EGR29183.1 - 0.00055 20.0 0.2 1.6 9.1 0.0 3.6 3 0 0 3 3 2 1 PPR repeat TPR_14 PF13428.6 EGR29183.1 - 0.0012 19.4 0.0 26 6.0 0.0 4.1 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGR29183.1 - 0.0018 18.8 7.9 0.11 13.2 0.0 5.5 6 1 0 6 6 6 1 Tetratricopeptide repeat DUF111 PF01969.17 EGR29183.1 - 0.0052 15.9 0.5 0.0063 15.7 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function DUF111 ANAPC3 PF12895.7 EGR29183.1 - 0.007 16.6 15.9 0.4 10.9 0.7 5.0 2 2 2 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EGR29183.1 - 0.012 16.3 0.0 11 6.8 0.0 3.3 3 2 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGR29183.1 - 0.012 15.8 0.0 23 5.2 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Med14 PF08638.11 EGR29183.1 - 0.021 14.3 0.6 0.039 13.4 0.6 1.7 1 1 0 1 1 1 0 Mediator complex subunit MED14 TPR_17 PF13431.6 EGR29183.1 - 0.023 15.1 1.0 80 4.0 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 EGR29183.1 - 0.069 13.5 0.2 12 6.3 0.0 3.4 2 1 2 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 EGR29183.1 - 0.21 11.7 0.1 0.21 11.7 0.1 5.4 4 3 1 6 6 6 0 MIT (microtubule interacting and transport) domain CorA PF01544.18 EGR29183.1 - 6.4 6.0 13.4 0.99 8.7 1.9 2.2 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein ADK PF00406.22 EGR29184.1 - 3.9e-53 179.6 0.0 5e-53 179.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGR29184.1 - 3.7e-21 76.0 0.0 7.1e-21 75.1 0.0 1.4 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 EGR29184.1 - 6.1e-13 48.5 0.1 1.3e-12 47.5 0.1 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 EGR29184.1 - 1e-05 25.7 0.0 2.4e-05 24.5 0.0 1.5 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 EGR29184.1 - 4.8e-05 23.1 0.1 0.056 13.1 0.0 2.4 2 0 0 2 2 2 2 Thymidylate kinase AAA_18 PF13238.6 EGR29184.1 - 0.00044 20.8 0.0 0.00076 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain UCH PF00443.29 EGR29185.1 - 4.5e-32 111.6 0.2 4.5e-32 111.6 0.2 2.2 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EGR29185.1 - 2.3e-15 57.0 6.5 2.3e-15 57.0 6.5 2.4 2 0 0 2 2 2 1 DUSP domain NAD_Gly3P_dh_N PF01210.23 EGR29185.1 - 0.15 12.1 0.1 0.3 11.1 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Ribosomal_S8 PF00410.19 EGR29186.1 - 2.9e-17 62.8 0.0 3.9e-17 62.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S8 Dynein_light PF01221.18 EGR29187.1 - 5.8e-28 97.0 1.3 1.3e-26 92.7 0.1 2.9 3 0 0 3 3 3 1 Dynein light chain type 1 SET PF00856.28 EGR29187.1 - 0.002 18.6 0.6 0.0072 16.7 0.0 2.1 2 0 0 2 2 2 1 SET domain Choline_transpo PF04515.12 EGR29190.1 - 3e-84 283.0 40.4 3e-84 283.0 40.4 2.9 3 0 0 3 3 3 1 Plasma-membrane choline transporter Pkinase PF00069.25 EGR29190.1 - 7.2e-59 199.3 0.0 2.2e-58 197.7 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29190.1 - 5.1e-28 98.1 0.1 1.8e-17 63.5 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Tim44 PF04280.15 EGR29191.1 - 2.1e-09 37.7 0.1 5.9e-09 36.2 0.1 1.8 1 0 0 1 1 1 1 Tim44-like domain LPP20 PF02169.16 EGR29191.1 - 4.7 7.6 7.5 10 6.5 3.6 3.1 3 0 0 3 3 3 0 LPP20 lipoprotein IATP PF04568.12 EGR29192.1 - 0.0089 16.4 4.1 0.015 15.7 4.1 1.5 1 0 0 1 1 1 1 Mitochondrial ATPase inhibitor, IATP FHIPEP PF00771.20 EGR29192.1 - 0.16 10.4 0.4 0.18 10.3 0.4 1.1 1 0 0 1 1 1 0 FHIPEP family ARA70 PF12489.8 EGR29192.1 - 0.22 11.7 9.1 0.37 11.0 9.1 1.6 1 1 0 1 1 1 0 Nuclear coactivator DNA_pol_B PF00136.21 EGR29193.1 - 8.4e-139 463.2 9.9 8.4e-139 463.2 9.9 2.7 2 1 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EGR29193.1 - 1.8e-69 234.5 13.0 1.8e-69 234.5 13.0 2.0 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EGR29193.1 - 3.5e-15 56.2 13.2 8.3e-15 55.0 13.2 1.7 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.6 EGR29193.1 - 0.028 14.4 1.8 0.17 11.9 1.8 2.4 1 1 0 1 1 1 0 RNase_H superfamily DUF4187 PF13821.6 EGR29193.1 - 0.03 14.1 3.0 0.082 12.7 3.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4187) DUF4261 PF14080.6 EGR29193.1 - 0.12 12.5 0.5 0.69 10.1 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4261) C2 PF00168.30 EGR29194.1 - 6.5e-13 48.9 0.4 3e-12 46.7 0.3 1.9 2 0 0 2 2 2 1 C2 domain Myb_Cef PF11831.8 EGR29194.1 - 0.03 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 pre-mRNA splicing factor component C2 PF00168.30 EGR29195.1 - 8.4e-13 48.5 4.4 2.3e-06 27.8 0.0 5.5 6 1 0 6 6 6 2 C2 domain TOC159_MAD PF11886.8 EGR29196.1 - 0.045 12.6 1.3 0.1 11.5 0.1 2.0 1 1 1 2 2 2 0 Translocase of chloroplast 159/132, membrane anchor domain tRNA-synt_2d PF01409.20 EGR29197.1 - 1.2e-84 283.6 0.1 1.6e-84 283.3 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EGR29197.1 - 1.4e-12 47.7 0.1 3.9e-12 46.3 0.1 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EGR29197.1 - 7.7e-08 32.0 0.0 0.00031 20.3 0.0 2.2 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain PheRS_DBD1 PF18552.1 EGR29197.1 - 5.8e-07 29.2 0.5 5.8e-07 29.2 0.5 2.1 3 0 0 3 3 3 1 PheRS DNA binding domain 1 tRNA-synt_2 PF00152.20 EGR29197.1 - 3.3e-05 23.1 0.7 0.0049 16.0 0.1 2.8 3 0 0 3 3 3 2 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 EGR29197.1 - 0.00021 21.3 0.1 0.00084 19.4 0.0 2.0 1 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Pkinase PF00069.25 EGR29198.1 - 5.3e-69 232.5 0.3 6.3e-69 232.3 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29198.1 - 4.6e-34 117.9 0.0 5.9e-34 117.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR29198.1 - 5.7e-08 31.9 0.1 8.1e-08 31.4 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR29198.1 - 0.0038 17.2 0.0 0.36 10.7 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EGR29198.1 - 0.0087 15.4 0.0 0.011 15.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR29198.1 - 0.024 14.0 0.4 0.041 13.2 0.4 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family E1-E2_ATPase PF00122.20 EGR29200.1 - 3.6e-26 91.8 0.0 3.6e-26 91.8 0.0 2.8 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EGR29200.1 - 3.5e-15 56.9 0.0 6.2e-07 29.9 0.0 2.6 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGR29200.1 - 7.3e-05 22.8 0.0 0.00023 21.2 0.0 1.9 1 0 0 1 1 1 1 Cation transport ATPase (P-type) P5-ATPase PF12409.8 EGR29200.1 - 0.00011 22.3 0.0 0.00047 20.3 0.0 2.2 1 0 0 1 1 1 1 P5-type ATPase cation transporter zf-TFIIB PF13453.6 EGR29200.1 - 0.11 11.8 0.2 0.51 9.7 0.0 2.1 2 0 0 2 2 2 0 Transcription factor zinc-finger RHH_3 PF12651.7 EGR29201.1 - 0.031 14.3 0.0 0.062 13.3 0.0 1.5 1 0 0 1 1 1 0 Ribbon-helix-helix domain zf_CCCH_5 PF18384.1 EGR29201.1 - 0.053 13.6 0.5 2 8.6 0.0 2.7 1 1 1 2 2 2 0 Unkempt Zinc finger domain 1 (Znf1) HAV_VP PF12944.7 EGR29201.1 - 0.071 13.1 1.1 0.11 12.5 0.4 1.6 1 1 1 2 2 2 0 Hepatitis A virus viral protein VP Transketolase_N PF00456.21 EGR29202.1 - 5.4e-37 127.5 0.0 7.8e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain E1_dh PF00676.20 EGR29202.1 - 6.6e-05 22.0 0.0 0.00017 20.7 0.0 1.6 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EGR29202.1 - 0.044 13.6 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPR_2 PF07719.17 EGR29203.1 - 1.2e-07 31.3 3.0 3.1e-05 23.7 0.0 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGR29203.1 - 1.7e-07 30.9 2.1 0.00012 22.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGR29203.1 - 1.8e-06 27.6 0.0 0.0015 18.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGR29203.1 - 6.6e-06 25.7 0.3 0.00012 21.7 0.0 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR29203.1 - 0.0001 22.4 0.0 0.0003 21.0 0.0 1.9 1 1 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGR29203.1 - 0.00013 22.4 0.1 0.0012 19.3 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGR29203.1 - 0.0077 16.9 0.0 0.038 14.7 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGR29203.1 - 0.012 15.3 0.6 2.7 7.7 0.0 2.6 2 0 0 2 2 2 0 TPR repeat TPR_12 PF13424.6 EGR29203.1 - 0.013 15.7 0.0 0.61 10.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGR29203.1 - 0.07 13.8 0.1 0.54 11.0 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGR29203.1 - 0.16 12.9 0.0 1.5 9.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RRM_1 PF00076.22 EGR29204.1 - 2.8e-13 49.5 0.0 5.3e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 EGR29204.1 - 9.7e-08 31.8 1.2 1.8e-07 30.9 1.2 1.5 1 0 0 1 1 1 1 Zinc knuckle RRM_5 PF13893.6 EGR29204.1 - 0.0048 16.5 0.0 0.0084 15.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGR29204.1 - 0.0093 15.8 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_3 PF08777.11 EGR29204.1 - 0.024 14.7 0.1 0.024 14.7 0.1 1.9 2 0 0 2 2 2 0 RNA binding motif RNA_bind PF08675.11 EGR29204.1 - 0.03 14.4 0.0 0.051 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA binding domain zf-CCHC_2 PF13696.6 EGR29204.1 - 0.097 12.5 0.6 0.2 11.5 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.6 EGR29204.1 - 0.12 12.4 0.3 0.12 12.4 0.3 2.3 2 0 0 2 2 2 0 Zinc knuckle RRM_1 PF00076.22 EGR29205.1 - 1.1e-22 79.6 0.1 4.7e-16 58.4 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RebB PF11747.8 EGR29205.1 - 0.36 11.0 3.0 0.64 10.2 3.0 1.4 1 0 0 1 1 1 0 Killing trait Bystin PF05291.11 EGR29207.1 - 0.00014 21.3 0.2 0.00017 21.0 0.2 1.1 1 0 0 1 1 1 1 Bystin EFhand_Ca_insen PF08726.10 EGR29207.1 - 0.0081 16.2 0.7 1 9.5 0.1 2.6 2 1 0 2 2 2 1 Ca2+ insensitive EF hand SurA_N_3 PF13624.6 EGR29207.1 - 0.0083 15.9 4.5 0.025 14.4 4.5 1.7 1 1 0 1 1 1 1 SurA N-terminal domain DAG_kinase_N PF14513.6 EGR29207.1 - 0.016 15.5 1.2 0.018 15.2 1.2 1.1 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus DUF1598 PF07643.11 EGR29207.1 - 0.016 15.5 0.1 0.035 14.3 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1598) EF-hand_7 PF13499.6 EGR29207.1 - 0.046 14.2 0.2 0.095 13.2 0.2 1.6 1 0 0 1 1 1 0 EF-hand domain pair SurA_N_2 PF13623.6 EGR29207.1 - 0.05 13.5 4.6 0.12 12.3 4.5 1.7 1 1 1 2 2 2 0 SurA N-terminal domain EF-hand_6 PF13405.6 EGR29207.1 - 0.46 10.5 0.1 0.46 10.5 0.1 2.5 3 0 0 3 3 3 0 EF-hand domain LRR_6 PF13516.6 EGR29208.1 - 1.6e-10 40.1 2.4 0.39 10.9 0.0 6.0 5 0 0 5 5 5 3 Leucine Rich repeat LRR_8 PF13855.6 EGR29208.1 - 0.00035 20.3 12.0 0.9 9.4 0.1 6.3 6 1 1 7 7 7 2 Leucine rich repeat LRR_4 PF12799.7 EGR29208.1 - 0.00055 20.3 25.4 0.98 9.9 1.5 7.0 3 2 4 7 7 7 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGR29208.1 - 0.0052 17.1 9.6 7.2 7.6 0.0 6.3 6 1 0 6 6 6 1 Leucine Rich Repeat Rsm22 PF09243.10 EGR29208.1 - 0.035 13.4 0.5 0.059 12.6 0.5 1.4 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 SAM_PNT PF02198.16 EGR29208.1 - 0.05 13.6 0.2 0.46 10.5 0.1 2.2 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain DUF5471 PF17565.2 EGR29208.1 - 0.11 12.8 0.3 0.42 10.9 0.1 2.1 1 1 0 1 1 1 0 Family of unknown function (DUF5471) DUF2666 PF10869.8 EGR29209.1 - 0.0011 19.1 4.0 0.0012 19.0 4.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2666) HDV_ag PF01517.18 EGR29209.1 - 0.48 10.2 4.8 0.5 10.1 4.8 1.1 1 0 0 1 1 1 0 Hepatitis delta virus delta antigen Apis_Csd PF11671.8 EGR29209.1 - 1.4 8.9 5.7 3.5 7.6 5.7 1.6 1 1 0 1 1 1 0 Complementary sex determiner protein MORN PF02493.20 EGR29210.1 - 1.8e-53 175.3 95.5 3.1e-07 29.9 4.0 9.7 10 0 0 10 10 10 9 MORN repeat Guanylate_kin PF00625.21 EGR29211.1 - 1.3e-40 139.1 5.0 9.5e-40 136.2 5.0 1.9 1 1 0 1 1 1 1 Guanylate kinase Rad17 PF03215.15 EGR29211.1 - 0.00013 21.9 0.0 0.00026 21.0 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 EGR29211.1 - 0.00042 20.3 0.1 0.028 14.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_14 PF13173.6 EGR29211.1 - 0.00092 19.2 1.2 0.0022 18.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EGR29211.1 - 0.0049 17.3 0.0 0.0094 16.4 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGR29211.1 - 0.013 16.1 0.1 0.021 15.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGR29211.1 - 0.013 15.9 0.0 0.026 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 EGR29211.1 - 0.014 14.9 0.0 0.033 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_17 PF13207.6 EGR29211.1 - 0.048 14.1 0.1 0.12 12.8 0.0 1.8 2 0 0 2 2 1 0 AAA domain ABC_tran PF00005.27 EGR29211.1 - 0.049 14.1 0.9 0.1 13.1 0.9 1.8 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 EGR29211.1 - 0.052 13.8 0.0 0.1 12.9 0.0 1.6 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGR29211.1 - 0.12 12.4 0.1 0.21 11.7 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 EGR29211.1 - 0.2 11.4 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Vta1 PF04652.16 EGR29212.1 - 6.7e-19 68.3 10.6 6.7e-19 68.3 10.6 3.0 3 1 0 3 3 3 1 Vta1 like DUF501 PF04417.12 EGR29212.1 - 1.1 9.0 4.5 3.8 7.3 4.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF501) Pkinase PF00069.25 EGR29214.1 - 2.4e-60 204.2 4.7 2.4e-60 204.2 4.7 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29214.1 - 4.5e-30 104.8 0.8 4.5e-30 104.8 0.8 2.0 3 0 0 3 3 3 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29214.1 - 3.9e-06 26.4 0.1 6.6e-05 22.4 0.1 2.4 2 0 0 2 2 2 1 Kinase-like DUF4145 PF13643.6 EGR29214.1 - 0.0031 17.6 0.7 0.018 15.1 0.1 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4145) Pkinase_fungal PF17667.1 EGR29214.1 - 0.021 13.6 0.0 0.021 13.6 0.0 2.6 3 0 0 3 3 3 0 Fungal protein kinase Kdo PF06293.14 EGR29214.1 - 0.033 13.5 0.3 0.063 12.6 0.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR29214.1 - 0.21 11.5 0.0 0.35 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family ATP-synt_G PF04718.15 EGR29214.1 - 3.3 8.6 7.3 1.6 9.6 1.2 3.2 3 0 0 3 3 3 0 Mitochondrial ATP synthase g subunit FTA2 PF13095.6 EGR29214.1 - 3.7 7.1 14.7 0.28 10.8 3.8 2.9 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Sulf_transp PF04143.14 EGR29215.1 - 8.3e-09 35.4 13.5 3.6e-06 26.8 2.3 2.7 1 1 2 3 3 3 2 Sulphur transport Rab5ip PF07019.12 EGR29215.1 - 0.026 15.1 4.8 0.5 11.0 0.2 2.2 2 0 0 2 2 2 0 Rab5-interacting protein (Rab5ip) Phosphorylase PF00343.20 EGR29216.1 - 0 1028.7 3.8 0 1028.7 3.8 1.3 2 0 0 2 2 2 1 Carbohydrate phosphorylase DUF4768 PF15989.5 EGR29216.1 - 0.11 12.5 1.6 0.34 10.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4768) CheR_N PF03705.15 EGR29216.1 - 0.22 11.2 3.3 18 5.1 1.6 3.7 3 0 0 3 3 3 0 CheR methyltransferase, all-alpha domain Ion_trans_2 PF07885.16 EGR29217.1 - 1.2e-10 41.1 5.9 1.2e-10 41.1 5.9 2.2 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 EGR29217.1 - 9.4e-10 38.4 0.0 2.1e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Formin_GBD_N PF18382.1 EGR29217.1 - 0.03 14.8 1.2 0.11 13.0 0.5 2.3 2 0 0 2 2 2 0 Formin N-terminal GTPase-binding domain E1-E2_ATPase PF00122.20 EGR29218.1 - 1.1e-23 83.7 0.0 3.4e-17 62.6 0.0 2.6 2 0 0 2 2 2 2 E1-E2 ATPase Hydrolase PF00702.26 EGR29218.1 - 2.3e-14 54.2 0.0 1.5e-08 35.2 0.0 2.9 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGR29218.1 - 4.6e-08 33.0 0.3 4.5e-07 29.8 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) DUF1840 PF08895.11 EGR29218.1 - 0.1 13.0 0.4 0.86 10.0 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Pkinase PF00069.25 EGR29219.1 - 1.8e-16 60.3 0.0 2e-16 60.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29219.1 - 0.0022 17.4 0.1 0.01 15.1 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase DUF1338 PF07063.13 EGR29219.1 - 0.076 12.2 0.0 0.082 12.1 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) Nop PF01798.18 EGR29221.1 - 3.7e-82 275.2 0.6 6.4e-82 274.5 0.6 1.4 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EGR29221.1 - 9.5e-18 64.3 2.2 3.6e-17 62.5 2.2 2.1 1 0 0 1 1 1 1 NOP5NT (NUC127) domain DUF3539 PF12058.8 EGR29221.1 - 0.064 13.4 0.0 0.27 11.4 0.0 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3539) UCH PF00443.29 EGR29222.1 - 7.2e-40 137.1 10.6 7.2e-40 137.1 10.6 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EGR29222.1 - 3.8e-16 59.5 15.6 2.4e-13 50.5 3.6 4.9 3 2 1 4 4 4 2 DUSP domain UCH_1 PF13423.6 EGR29222.1 - 1.4e-13 51.1 3.9 1.4e-13 51.1 3.9 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase YqbF PF14553.6 EGR29222.1 - 0.036 13.9 0.0 0.16 11.9 0.0 2.2 1 0 0 1 1 1 0 YqbF, hypothetical protein domain zf-CHY PF05495.12 EGR29222.1 - 2 9.0 6.7 0.44 11.1 2.7 2.0 2 0 0 2 2 2 0 CHY zinc finger DUF2197 PF09963.9 EGR29222.1 - 2.3 8.5 5.7 19 5.6 0.1 3.3 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) CPSF_A PF03178.15 EGR29224.1 - 5.7e-15 55.4 0.8 7.4e-15 55.1 0.8 1.1 1 0 0 1 1 1 1 CPSF A subunit region MutS_V PF00488.21 EGR29225.1 - 1.1e-62 211.4 0.5 3e-62 210.0 0.5 1.7 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGR29225.1 - 9e-35 120.6 0.3 9e-35 120.6 0.3 2.8 2 1 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EGR29225.1 - 2.1e-31 108.5 0.2 7.2e-31 106.7 0.2 2.0 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 EGR29225.1 - 6.5e-06 26.4 4.4 6.5e-06 26.4 4.4 3.6 3 1 0 3 3 3 1 MutS family domain IV MutS_II PF05188.17 EGR29225.1 - 0.00054 20.2 0.0 0.00054 20.2 0.0 3.5 5 0 0 5 5 5 1 MutS domain II UQ_con PF00179.26 EGR29226.1 - 8.9e-05 22.2 0.4 0.00015 21.4 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Spermine_synth PF01564.17 EGR29227.1 - 1.2e-20 73.8 0.4 1.9e-20 73.1 0.4 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase domain AdoMet_dc PF02675.15 EGR29227.1 - 2.8e-17 62.9 0.0 5.3e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine decarboxylase Spermine_synt_N PF17284.2 EGR29227.1 - 4.6e-11 42.4 2.0 5.4e-10 39.0 0.1 3.0 4 0 0 4 4 4 1 Spermidine synthase tetramerisation domain RrnaAD PF00398.20 EGR29227.1 - 0.021 13.9 0.0 0.039 13.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase IL17R_D_N PF16742.5 EGR29227.1 - 0.064 13.3 0.2 0.17 11.9 0.2 1.8 1 0 0 1 1 1 0 N-terminus of interleukin 17 receptor D Methyltransf_25 PF13649.6 EGR29227.1 - 0.14 12.9 0.1 0.89 10.3 0.0 2.4 3 0 0 3 3 3 0 Methyltransferase domain Ras PF00071.22 EGR29228.1 - 2.4e-52 176.8 0.4 3e-52 176.5 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR29228.1 - 7.7e-37 126.2 0.1 1.6e-36 125.2 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR29228.1 - 2.1e-19 69.7 0.1 2.6e-19 69.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGR29228.1 - 9.8e-10 38.2 0.2 1.3e-09 37.8 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGR29228.1 - 3.1e-08 33.7 0.1 5e-08 33.0 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGR29228.1 - 3e-07 30.5 0.1 0.0003 20.7 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGR29228.1 - 8e-05 22.3 0.1 0.0008 19.0 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGR29228.1 - 0.0004 19.9 0.2 0.00085 18.8 0.2 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 EGR29228.1 - 0.00057 20.0 4.5 0.048 13.7 0.0 3.0 1 1 2 3 3 3 2 Dynamin family DoxA PF07680.11 EGR29228.1 - 0.0018 18.2 0.0 0.0028 17.6 0.0 1.3 1 0 0 1 1 1 1 TQO small subunit DoxA FeoB_N PF02421.18 EGR29228.1 - 0.052 13.1 0.1 0.13 11.8 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B GCP5-Mod21 PF14609.6 EGR29229.1 - 0.0027 16.2 0.2 0.0029 16.0 0.2 1.2 1 0 0 1 1 1 1 gamma-Tubulin ring complex non-core subunit mod21 Pro_isomerase PF00160.21 EGR29230.1 - 1.1e-49 168.8 0.1 1.2e-49 168.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Diphthami_syn_2 PF01902.17 EGR29231.1 - 2.5e-38 131.8 0.4 1.1e-35 123.1 0.4 2.9 1 1 0 1 1 1 1 Diphthamide synthase Peptidase_M22 PF00814.25 EGR29231.1 - 0.0031 17.2 0.0 0.0066 16.2 0.0 1.5 1 1 0 1 1 1 1 Glycoprotease family tRNA_Me_trans PF03054.16 EGR29231.1 - 0.0036 16.1 0.0 0.0069 15.2 0.0 1.4 1 0 0 1 1 1 1 tRNA methyl transferase QueC PF06508.13 EGR29231.1 - 0.013 15.1 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC DUF1981 PF09324.10 EGR29232.1 - 1.4e-07 31.2 2.4 1.4e-07 31.2 2.4 6.0 5 2 0 5 5 5 1 Domain of unknown function (DUF1981) DCB PF16213.5 EGR29232.1 - 0.012 15.3 0.1 0.012 15.3 0.1 5.0 3 1 1 4 4 4 0 Dimerisation and cyclophilin-binding domain of Mon2 Kinesin PF00225.23 EGR29233.1 - 2.7e-95 319.1 0.1 2.7e-95 319.1 0.1 2.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGR29233.1 - 6.4e-20 71.6 0.0 6.4e-20 71.6 0.0 3.9 4 2 1 5 5 5 1 Microtubule binding Pkinase PF00069.25 EGR29236.1 - 1.6e-69 234.2 0.3 1.6e-69 234.2 0.3 2.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29236.1 - 2.4e-35 122.1 0.1 2.4e-35 122.1 0.1 2.7 2 1 1 3 3 3 1 Protein tyrosine kinase APH PF01636.23 EGR29236.1 - 0.5 10.2 0.0 0.5 10.2 0.0 2.6 2 1 1 3 3 3 0 Phosphotransferase enzyme family SF-assemblin PF06705.11 EGR29237.1 - 1.2e-12 47.7 41.8 2.1e-10 40.4 33.7 2.2 1 1 1 2 2 2 2 SF-assemblin/beta giardin ApoO PF09769.9 EGR29237.1 - 0.04 13.9 6.0 1.2 9.1 0.2 3.1 2 1 1 3 3 3 0 Apolipoprotein O adh_short PF00106.25 EGR29238.1 - 8.9e-18 64.4 0.1 1.5e-14 54.0 0.2 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGR29238.1 - 1.8e-12 47.4 0.0 2.9e-09 36.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGR29238.1 - 0.087 12.7 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 KR domain Pkinase PF00069.25 EGR29239.1 - 6.7e-57 192.8 0.1 9.7e-57 192.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29239.1 - 2.5e-27 95.8 0.0 3.9e-27 95.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR29239.1 - 2.4e-06 26.6 0.9 7e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGR29239.1 - 0.078 12.3 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR29239.1 - 0.19 11.6 0.1 0.28 11.1 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family UPF0004 PF00919.20 EGR29240.1 - 1.2e-30 105.4 0.3 2.3e-30 104.5 0.3 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 EGR29240.1 - 3.4e-16 60.1 0.1 2e-15 57.6 0.0 2.2 2 1 1 3 3 3 1 Radical SAM superfamily RRG8 PF17068.5 EGR29240.1 - 0.0056 16.1 0.5 0.0084 15.5 0.5 1.3 1 0 0 1 1 1 1 Required for respiratory growth protein 8 mitochondrial SAS-6_N PF16531.5 EGR29241.1 - 3.2e-23 82.1 6.7 5.6e-23 81.3 6.3 1.6 2 0 0 2 2 2 1 Centriolar protein SAS N-terminal CSD PF00313.22 EGR29241.1 - 0.016 15.0 0.2 0.13 12.2 0.4 2.2 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain Kunitz_legume PF00197.18 EGR29241.1 - 0.08 12.9 0.9 0.19 11.7 0.5 1.8 2 1 0 2 2 2 0 Trypsin and protease inhibitor Pkinase PF00069.25 EGR29242.1 - 6.8e-36 124.0 8.5 1e-18 67.7 0.2 3.1 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29242.1 - 2.9e-14 53.0 4.4 2.9e-06 26.7 0.1 3.5 2 2 0 2 2 2 2 Protein tyrosine kinase CDC45 PF02724.14 EGR29242.1 - 1.8e-05 23.3 8.0 1.8e-05 23.3 8.0 2.3 3 0 0 3 3 3 1 CDC45-like protein YL1 PF05764.13 EGR29242.1 - 0.0015 18.7 13.2 0.0015 18.7 13.2 3.2 3 0 0 3 3 3 1 YL1 nuclear protein Neur_chan_memb PF02932.16 EGR29242.1 - 0.1 12.6 3.8 0.23 11.5 3.8 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.6 EGR29242.1 - 0.31 10.3 12.0 0.53 9.6 12.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ndc1_Nup PF09531.10 EGR29242.1 - 0.5 9.0 4.1 0.6 8.7 4.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GAGA_bind PF06217.12 EGR29242.1 - 0.72 10.1 15.1 0.59 10.4 12.4 2.1 2 0 0 2 2 2 0 GAGA binding protein-like family LMBR1 PF04791.16 EGR29242.1 - 1.4 7.8 8.4 2.3 7.0 8.4 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DDHD PF02862.17 EGR29242.1 - 1.4 9.0 10.3 0.34 11.0 6.5 1.9 2 0 0 2 2 2 0 DDHD domain Zip PF02535.22 EGR29242.1 - 1.8 7.7 6.1 3 7.0 6.1 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter AAA_11 PF13086.6 EGR29242.1 - 5.2 6.8 18.4 14 5.4 18.4 1.7 1 0 0 1 1 1 0 AAA domain Presenilin PF01080.17 EGR29242.1 - 5.5 5.6 17.2 12 4.5 17.2 1.5 1 0 0 1 1 1 0 Presenilin Paramyxo_ncap PF00973.19 EGR29242.1 - 7.1 5.4 12.2 12 4.7 12.2 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Metallophos PF00149.28 EGR29243.1 - 7.5e-35 121.3 0.2 1.8e-34 120.0 0.2 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Cullin PF00888.22 EGR29244.1 - 2.4e-114 383.2 47.1 2.4e-114 383.2 47.1 1.9 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 EGR29244.1 - 8.2e-20 70.6 2.7 8.2e-20 70.6 2.7 3.9 4 0 0 4 4 4 1 Cullin protein neddylation domain DUF1525 PF07511.11 EGR29244.1 - 0.17 12.1 1.0 0.51 10.5 1.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1525) DUF624 PF04854.14 EGR29244.1 - 0.83 9.8 3.0 31 4.7 0.1 3.2 2 0 0 2 2 2 0 Protein of unknown function, DUF624 SK_channel PF03530.14 EGR29244.1 - 7.3 6.6 6.3 4.2 7.4 0.3 3.0 3 0 0 3 3 3 0 Calcium-activated SK potassium channel NIF PF03031.18 EGR29245.1 - 5.3e-50 169.2 1.4 9.3e-50 168.4 1.4 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase MMR_HSR1_C PF08438.10 EGR29245.1 - 0.063 13.9 0.5 0.13 12.9 0.5 1.5 1 0 0 1 1 1 0 GTPase of unknown function C-terminal Pkinase PF00069.25 EGR29246.1 - 8.1e-75 251.6 0.5 1.1e-74 251.2 0.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29246.1 - 2e-39 135.5 0.0 2.5e-39 135.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29246.1 - 1.2e-06 28.0 0.1 8.1e-06 25.3 0.0 1.9 1 1 0 2 2 2 1 Kinase-like Ndufs5 PF10200.9 EGR29246.1 - 0.02 15.1 1.7 0.21 11.9 0.0 2.6 2 0 0 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa TsaE PF02367.17 EGR29246.1 - 0.11 12.5 0.3 0.47 10.5 0.2 2.0 1 1 1 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MORN PF02493.20 EGR29249.1 - 7.1e-12 44.5 38.8 0.00062 19.5 1.0 8.2 8 1 1 9 9 9 5 MORN repeat Cation_efflux PF01545.21 EGR29250.1 - 3.2e-12 46.6 6.7 5.6e-12 45.8 6.7 1.4 1 1 0 1 1 1 1 Cation efflux family PRA1 PF03208.19 EGR29250.1 - 5.7 6.6 12.3 0.56 9.8 6.1 2.1 2 0 0 2 2 2 0 PRA1 family protein DnaJ_C PF01556.18 EGR29251.1 - 5.3e-35 120.7 0.6 9.8e-35 119.8 0.6 1.5 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGR29251.1 - 2.6e-16 59.5 1.3 5.4e-16 58.5 1.3 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGR29251.1 - 6.4e-11 42.5 20.4 1.6e-10 41.2 20.4 1.7 1 0 0 1 1 1 1 DnaJ central domain TackOD1 PF18551.1 EGR29251.1 - 0.04 13.6 0.6 0.04 13.6 0.6 2.4 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DUF1258 PF06869.12 EGR29251.1 - 0.91 9.0 12.3 3.6 7.0 6.7 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) Anti-TRAP PF15777.5 EGR29251.1 - 0.96 9.5 16.3 0.27 11.2 2.4 2.4 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein DZR PF12773.7 EGR29251.1 - 4.7 7.3 13.2 11 6.2 3.0 2.3 1 1 1 2 2 2 0 Double zinc ribbon HypA PF01155.19 EGR29251.1 - 6.8 6.7 13.9 3.7 7.6 2.7 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA SNF2_N PF00176.23 EGR29252.1 - 8.7e-66 222.0 2.3 1.4e-65 221.3 2.3 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGR29252.1 - 5.1e-21 75.1 0.0 3.1e-20 72.6 0.0 2.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Cwf_Cwc_15 PF04889.12 EGR29252.1 - 1.6 8.4 25.5 2.7 7.7 25.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Mg_chelatase_C PF13335.6 EGR29253.1 - 0.021 15.4 0.7 0.021 15.4 0.7 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal Abi_C PF14355.6 EGR29253.1 - 5.2 7.2 5.8 3.5 7.8 0.5 2.4 2 0 0 2 2 2 0 Abortive infection C-terminus UNC119_bdg PF15435.6 EGR29254.1 - 0.055 13.0 0.3 0.068 12.7 0.3 1.1 1 0 0 1 1 1 0 UNC119-binding protein C5orf30 homologue PIG-H PF10181.9 EGR29254.1 - 0.085 12.7 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 GPI-GlcNAc transferase complex, PIG-H component PX PF00787.24 EGR29255.1 - 2.4e-15 56.5 0.0 2.4e-15 56.5 0.0 2.8 1 1 1 2 2 2 1 PX domain Helicase_C PF00271.31 EGR29257.1 - 1.8e-18 66.9 0.4 8.5e-18 64.7 0.1 2.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGR29257.1 - 1.4e-15 57.5 0.0 4.4e-15 55.9 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EGR29257.1 - 1e-05 25.6 0.0 2.7e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DUF4130 PF13566.6 EGR29257.1 - 0.014 15.5 0.0 0.027 14.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4130 E2 PF08199.11 EGR29258.1 - 0.81 9.7 6.2 1.9 8.5 0.3 2.6 2 1 0 2 2 2 0 Bacteriophage E2-like protein Ras PF00071.22 EGR29259.1 - 6.8e-59 198.1 2.6 7.8e-59 197.9 2.6 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR29259.1 - 3.5e-34 117.6 1.7 6.3e-34 116.8 1.7 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR29259.1 - 8e-15 54.7 1.0 9.3e-15 54.5 1.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGR29259.1 - 4.5e-06 26.2 0.4 5.7e-06 25.9 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGR29259.1 - 1.4e-05 24.7 0.8 2.2e-05 24.1 0.8 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGR29259.1 - 1.5e-05 25.0 1.1 6.4e-05 23.0 0.6 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGR29259.1 - 1.6e-05 24.5 1.2 4.6e-05 23.0 1.2 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 EGR29259.1 - 0.00022 20.7 0.2 0.0003 20.3 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 EGR29259.1 - 0.014 14.8 0.2 0.035 13.5 0.0 1.7 2 1 0 2 2 2 0 Bacterial TniB protein EF-hand_10 PF14788.6 EGR29259.1 - 0.028 14.3 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 EF hand DUF3067 PF11267.8 EGR29259.1 - 0.057 14.0 0.1 0.093 13.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3067) UQ_con PF00179.26 EGR29260.1 - 1.9e-49 166.9 0.3 2.2e-49 166.7 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGR29260.1 - 0.0012 19.2 0.4 0.0017 18.6 0.4 1.5 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EGR29260.1 - 0.004 16.9 0.0 0.0046 16.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RNA_pol_Rpb1_5 PF04998.17 EGR29261.1 - 3.4e-91 305.4 1.2 3.4e-91 305.4 1.2 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGR29261.1 - 1.6e-64 217.1 0.1 4.8e-64 215.6 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_1 PF04997.12 EGR29261.1 - 1.1e-52 179.3 14.4 1.1e-52 179.3 14.4 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_3 PF04983.18 EGR29261.1 - 6.2e-41 139.9 0.9 2.4e-40 138.0 0.1 2.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EGR29261.1 - 3.3e-23 81.7 0.1 1.7e-22 79.4 0.1 2.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RXT2_N PF08595.11 EGR29261.1 - 0.004 17.2 3.7 0.004 17.2 3.7 2.5 2 0 0 2 2 2 1 RXT2-like, N-terminal RNA_pol_Rpb1_6 PF04992.14 EGR29261.1 - 0.0063 16.4 0.1 0.0063 16.4 0.1 4.4 3 1 1 4 4 4 2 RNA polymerase Rpb1, domain 6 PHM7_cyt PF14703.6 EGR29262.1 - 2.3e-05 24.7 1.2 2.3e-05 24.7 1.2 3.0 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter DUF1378 PF07125.11 EGR29262.1 - 0.75 10.0 3.3 2.2 8.5 3.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) Inhibitor_I29 PF08246.12 EGR29262.1 - 1.2 9.6 8.3 0.2 12.1 3.3 2.4 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) Rhomboid PF01694.22 EGR29263.1 - 1.7e-28 99.5 17.3 1.7e-28 99.5 17.3 1.8 2 0 0 2 2 2 1 Rhomboid family DUF4257 PF14074.6 EGR29263.1 - 1.2 9.4 7.8 0.32 11.2 2.6 2.6 2 1 0 3 3 3 0 Protein of unknown function (DUF4257) RNB PF00773.19 EGR29265.1 - 1.2e-88 297.6 4.0 1.2e-88 297.6 4.0 3.0 2 1 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 EGR29265.1 - 1.1e-09 38.2 0.0 5.2e-09 36.0 0.0 2.3 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) WD40 PF00400.32 EGR29266.1 - 3.4e-16 59.3 1.5 0.00015 22.5 0.1 4.6 4 1 1 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR29266.1 - 0.00051 20.3 0.1 0.011 16.0 0.0 2.9 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGR29266.1 - 0.0089 15.4 1.3 0.0097 15.3 0.4 1.6 2 0 0 2 2 2 1 WD40-like domain Hira PF07569.11 EGR29266.1 - 0.16 11.7 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 TUP1-like enhancer of split RL11D PF11088.8 EGR29267.1 - 0.052 13.8 0.1 0.12 12.6 0.1 1.8 1 1 0 1 1 1 0 Glycoprotein encoding membrane proteins RL5A and RL6 LodA_N PF17990.1 EGR29268.1 - 0.33 10.8 5.0 0.39 10.6 5.0 1.0 1 0 0 1 1 1 0 L-Lysine epsilon oxidase N-terminal RYDR_ITPR PF01365.21 EGR29269.1 - 3.2e-07 30.0 4.0 3.2e-07 30.0 4.0 3.2 1 1 0 2 2 2 1 RIH domain RIH_assoc PF08454.11 EGR29270.1 - 7.6e-32 109.2 6.1 7.6e-32 109.2 6.1 4.5 4 2 1 5 5 5 2 RyR and IP3R Homology associated XPG_I_2 PF12813.7 EGR29270.1 - 1.3 8.5 7.6 2.1 7.8 2.7 2.5 2 0 0 2 2 2 0 XPG domain containing Cytochrom_C1 PF02167.15 EGR29271.1 - 3.6e-44 151.1 0.7 5.4e-44 150.5 0.3 1.5 1 1 1 2 2 2 1 Cytochrome C1 family Cytochrom_C PF00034.21 EGR29271.1 - 0.032 15.3 0.0 0.072 14.2 0.0 1.7 1 0 0 1 1 1 0 Cytochrome c Cytochrome_CBB3 PF13442.6 EGR29271.1 - 0.085 13.2 0.0 0.23 11.8 0.0 1.8 1 0 0 1 1 1 0 Cytochrome C oxidase, cbb3-type, subunit III Pirin PF02678.16 EGR29272.1 - 8.8e-24 83.6 0.0 2.2e-23 82.3 0.0 1.7 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EGR29272.1 - 3.6e-20 72.3 0.1 1.2e-19 70.5 0.1 1.9 2 0 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EGR29272.1 - 0.057 13.1 0.1 0.15 11.8 0.0 1.6 2 0 0 2 2 2 0 Cupin domain HILPDA PF15220.6 EGR29272.1 - 0.21 11.7 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 Hypoxia-inducible lipid droplet-associated DUF4891 PF16232.5 EGR29273.1 - 0.12 12.9 1.2 0.12 12.9 1.2 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4891) DUF3450 PF11932.8 EGR29273.1 - 0.13 11.6 5.8 0.16 11.3 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Sec2p PF06428.11 EGR29273.1 - 0.2 11.6 8.8 2.1 8.4 5.4 2.2 1 1 1 2 2 2 0 GDP/GTP exchange factor Sec2p PPP4R2 PF09184.11 EGR29274.1 - 1.1e-15 58.0 1.1 1.8e-15 57.3 1.1 1.3 1 0 0 1 1 1 1 PPP4R2 PTH2 PF01981.16 EGR29275.1 - 1.1e-31 109.5 0.4 1.2e-31 109.4 0.4 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 AAA_6 PF12774.7 EGR29276.1 - 5.1e-146 485.8 12.4 2.3e-116 388.4 0.1 5.5 5 0 0 5 5 5 2 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 EGR29276.1 - 7.5e-137 457.3 28.4 7.5e-137 457.3 28.4 5.9 3 2 1 5 5 3 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EGR29276.1 - 6.1e-106 354.9 31.2 6.1e-106 354.9 31.2 6.9 8 0 0 8 8 6 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EGR29276.1 - 2.2e-85 286.1 18.6 7.3e-77 258.2 0.1 5.9 6 0 0 6 6 5 2 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EGR29276.1 - 1.7e-71 239.9 8.4 1.7e-71 239.9 8.4 5.3 4 0 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 EGR29276.1 - 3.4e-70 235.2 2.4 3.2e-66 222.3 0.1 4.1 3 0 0 3 3 3 2 P-loop containing dynein motor region MT PF12777.7 EGR29276.1 - 1.8e-43 148.9 7.8 8.6e-43 146.7 7.8 2.2 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 EGR29276.1 - 1.7e-25 89.5 7.4 1.9e-25 89.4 2.0 3.9 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EGR29276.1 - 4.3e-21 75.3 0.1 1.8e-06 28.0 0.0 6.0 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EGR29276.1 - 1.5e-18 66.9 0.3 1.7e-17 63.4 0.3 3.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EGR29276.1 - 8.2e-06 26.1 3.8 0.57 10.5 0.0 6.2 6 0 0 6 6 6 2 AAA domain AAA PF00004.29 EGR29276.1 - 1e-05 26.0 1.0 0.091 13.2 0.0 4.7 4 0 0 4 4 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGR29276.1 - 0.00012 22.5 0.0 0.21 12.0 0.0 4.5 2 1 1 3 3 3 1 AAA ATPase domain T2SSE PF00437.20 EGR29276.1 - 0.0019 17.3 0.2 0.0071 15.4 0.2 2.0 1 0 0 1 1 1 1 Type II/IV secretion system protein NACHT PF05729.12 EGR29276.1 - 0.0031 17.4 0.1 0.031 14.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain ResIII PF04851.15 EGR29276.1 - 0.0032 17.5 0.0 0.0032 17.5 0.0 6.0 6 0 0 6 6 4 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 EGR29276.1 - 0.0045 17.4 0.9 20 5.6 0.0 4.9 4 0 0 4 4 3 0 RNA helicase AAA_30 PF13604.6 EGR29276.1 - 0.0056 16.4 1.8 0.86 9.3 0.0 2.9 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EGR29276.1 - 0.0064 16.2 0.4 0.16 11.6 0.0 3.0 3 0 0 3 3 2 1 Sigma-54 interaction domain RsgA_GTPase PF03193.16 EGR29276.1 - 0.0065 16.4 2.1 0.072 13.0 0.0 3.7 3 0 0 3 3 3 1 RsgA GTPase Dynein_heavy PF03028.15 EGR29276.1 - 0.0069 16.5 0.0 0.22 11.6 0.0 3.5 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain YqzH PF14164.6 EGR29276.1 - 0.032 14.3 0.7 0.94 9.6 0.1 4.2 3 0 0 3 3 1 0 YqzH-like protein AAA_29 PF13555.6 EGR29276.1 - 0.37 10.5 6.2 0.54 10.0 0.2 3.1 3 0 0 3 3 2 0 P-loop containing region of AAA domain PspB PF06667.12 EGR29276.1 - 0.53 10.4 2.5 7.1 6.8 2.5 3.1 1 0 0 1 1 1 0 Phage shock protein B Mg_chelatase PF01078.21 EGR29276.1 - 1.1 8.6 4.0 2.9 7.2 0.0 3.4 5 0 0 5 5 4 0 Magnesium chelatase, subunit ChlI FtsK_SpoIIIE PF01580.18 EGR29276.1 - 1.4 8.3 5.0 2.5 7.4 0.1 3.8 4 0 0 4 4 4 0 FtsK/SpoIIIE family DUF4094 PF13334.6 EGR29276.1 - 1.4 9.4 4.1 13 6.3 1.0 4.7 2 0 0 2 2 1 0 Domain of unknown function (DUF4094) MMR_HSR1 PF01926.23 EGR29276.1 - 6.1 7.0 6.2 3.6 7.7 0.1 3.9 4 0 0 4 4 3 0 50S ribosome-binding GTPase Roc PF08477.13 EGR29276.1 - 9.1 6.5 9.3 2.3 8.5 0.1 4.9 5 0 0 5 5 4 0 Ras of Complex, Roc, domain of DAPkinase ABA_GPCR PF12430.8 EGR29278.1 - 5e-18 65.5 7.2 6.4e-18 65.2 7.2 1.0 1 0 0 1 1 1 1 Abscisic acid G-protein coupled receptor Peptidase_M14 PF00246.24 EGR29279.1 - 4.9e-23 82.3 0.3 1.9e-22 80.4 0.1 1.8 1 1 1 2 2 2 1 Zinc carboxypeptidase TraI_2_C PF07515.11 EGR29279.1 - 0.1 12.6 0.6 4.5 7.2 0.1 2.2 1 1 1 2 2 2 0 Putative conjugal transfer nickase/helicase TraI C-term LRR_4 PF12799.7 EGR29281.1 - 1e-17 63.9 40.9 4.4e-07 30.1 8.5 4.8 2 1 2 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGR29281.1 - 1.7e-12 46.9 28.0 5.3e-05 22.9 12.8 4.3 1 1 3 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 EGR29281.1 - 6e-08 32.4 19.6 0.0011 18.6 7.6 3.0 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 EGR29281.1 - 1.8e-06 27.5 25.9 0.24 11.5 0.2 7.5 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 EGR29281.1 - 0.001 19.3 24.3 0.75 10.6 0.1 6.7 7 0 0 7 7 7 2 Leucine Rich Repeat Pkinase PF00069.25 EGR29282.1 - 2.8e-26 92.5 0.7 3.4e-26 92.2 0.7 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29282.1 - 1.8e-13 50.4 0.1 2.8e-13 49.8 0.1 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR29282.1 - 1.7e-10 40.3 0.0 4.2e-10 39.0 0.2 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGR29282.1 - 0.077 12.9 0.0 0.16 11.8 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF3823 PF12866.7 EGR29282.1 - 0.28 11.5 2.4 0.27 11.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3823) N-terminal domain Arf PF00025.21 EGR29283.1 - 1.1e-30 106.3 0.7 1.3e-30 106.2 0.7 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGR29283.1 - 1e-10 41.5 0.0 1.1e-10 41.3 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR29283.1 - 3.7e-09 36.8 0.1 7.6e-09 35.8 0.0 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EGR29283.1 - 7.8e-05 22.3 0.0 9.5e-05 22.0 0.0 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EGR29283.1 - 0.00016 21.0 0.2 0.00063 19.0 0.2 1.7 1 1 0 1 1 1 1 G-protein alpha subunit NOG1 PF06858.14 EGR29283.1 - 0.0027 17.5 1.1 0.0078 16.0 0.2 2.2 2 1 0 2 2 2 1 Nucleolar GTP-binding protein 1 (NOG1) SRPRB PF09439.10 EGR29283.1 - 0.013 14.9 0.0 0.017 14.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGR29283.1 - 0.019 14.3 0.0 0.023 14.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGR29283.1 - 0.044 13.9 0.0 0.084 13.0 0.0 1.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase TPM_phosphatase PF04536.14 EGR29283.1 - 0.045 13.9 0.1 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 TPM domain HECW_N PF16562.5 EGR29283.1 - 0.061 13.1 1.2 0.27 11.0 0.1 2.0 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 RsgA_GTPase PF03193.16 EGR29283.1 - 0.07 13.0 0.1 0.087 12.7 0.1 1.1 1 0 0 1 1 1 0 RsgA GTPase Pex2_Pex12 PF04757.14 EGR29284.1 - 2.4 7.7 5.6 6 6.4 5.6 1.9 1 1 0 1 1 1 0 Pex2 / Pex12 amino terminal region ABC2_membrane_3 PF12698.7 EGR29284.1 - 4 6.4 9.8 6.1 5.8 9.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Peptidase_S64 PF08192.11 EGR29284.1 - 4.8 5.6 21.9 5.7 5.3 21.9 1.0 1 0 0 1 1 1 0 Peptidase family S64 Ndc1_Nup PF09531.10 EGR29284.1 - 6.8 5.3 11.4 8 5.0 11.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UCH PF00443.29 EGR29288.1 - 6.5e-44 150.3 8.4 6.5e-44 150.3 8.4 5.7 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR29288.1 - 9.9e-26 91.1 8.4 9.9e-26 91.1 8.4 4.5 4 1 0 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase EF-hand_7 PF13499.6 EGR29288.1 - 0.016 15.6 0.9 0.16 12.5 0.4 3.2 2 0 0 2 2 2 0 EF-hand domain pair UN_NPL4 PF11543.8 EGR29288.1 - 0.024 15.1 0.8 0.23 12.0 0.8 2.8 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 EF-hand_6 PF13405.6 EGR29288.1 - 0.24 11.4 1.9 0.83 9.8 0.1 3.0 2 0 0 2 2 2 0 EF-hand domain DZR PF12773.7 EGR29288.1 - 2.1 8.4 13.0 1.9 8.6 3.0 2.9 2 0 0 2 2 2 0 Double zinc ribbon H_PPase PF03030.16 EGR29289.1 - 1.3e-239 797.2 23.3 1.5e-239 797.0 23.3 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase Neurensin PF14927.6 EGR29289.1 - 0.3 10.8 2.9 0.53 10.0 1.0 2.4 2 0 0 2 2 2 0 Neurensin SHIPPO-rpt PF07004.12 EGR29290.1 - 2.6e-05 24.9 12.0 0.31 12.0 0.2 5.2 5 0 0 5 5 5 4 Sperm-tail PG-rich repeat HEAT PF02985.22 EGR29291.1 - 8.7e-14 50.5 2.1 0.0014 18.7 0.0 8.8 9 0 0 9 9 9 2 HEAT repeat HEAT_2 PF13646.6 EGR29291.1 - 2.8e-11 43.7 0.0 3.3e-05 24.2 0.0 5.0 2 2 3 5 5 5 3 HEAT repeats Cnd1 PF12717.7 EGR29291.1 - 3.6e-11 43.4 9.4 0.001 19.2 0.2 4.0 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGR29291.1 - 6.2e-05 23.5 5.6 0.34 11.5 0.1 5.0 3 1 3 6 6 6 3 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGR29291.1 - 0.01 16.3 0.3 18 6.0 0.1 4.6 6 0 0 6 6 6 0 HEAT-like repeat G-gamma PF00631.22 EGR29291.1 - 0.088 12.8 0.3 0.29 11.1 0.0 2.1 2 0 0 2 2 2 0 GGL domain Arm PF00514.23 EGR29291.1 - 0.89 9.7 3.3 16 5.7 0.1 4.2 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat MatE PF01554.18 EGR29292.1 - 5.5e-28 97.7 15.8 5.5e-22 78.1 10.9 2.3 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EGR29292.1 - 6.7e-06 26.2 4.7 6.7e-06 26.2 4.7 2.7 2 1 0 2 2 2 1 Polysaccharide biosynthesis C-terminal domain FtsX PF02687.21 EGR29292.1 - 9.7 6.7 15.4 2.4 8.7 6.5 3.5 2 1 1 3 3 3 0 FtsX-like permease family ANAPC10 PF03256.16 EGR29293.1 - 1.9e-26 92.9 0.1 5.3e-25 88.1 0.1 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) Pkinase PF00069.25 EGR29294.1 - 2.3e-29 102.6 9.4 8.7e-29 100.7 1.3 3.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29294.1 - 2.5e-09 36.8 2.1 2.2e-07 30.4 2.1 3.3 1 1 0 1 1 1 1 Protein tyrosine kinase FANCI_S1-cap PF14674.6 EGR29294.1 - 0.17 12.0 0.8 0.86 9.7 0.1 2.4 2 0 0 2 2 2 0 FANCI solenoid 1 cap Pkinase PF00069.25 EGR29296.1 - 2.2e-51 174.8 0.8 3.4e-51 174.2 0.2 1.6 2 0 0 2 2 2 1 Protein kinase domain EF-hand_1 PF00036.32 EGR29296.1 - 8.6e-27 90.7 9.9 4.5e-07 29.0 0.4 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGR29296.1 - 5.8e-22 77.9 3.1 3.3e-11 43.5 0.1 3.0 2 1 0 2 2 2 2 EF-hand domain pair Pkinase_Tyr PF07714.17 EGR29296.1 - 1.9e-20 73.3 0.0 3.3e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_6 PF13405.6 EGR29296.1 - 2.1e-20 70.9 9.8 9.3e-07 28.3 0.1 4.9 5 0 0 5 5 4 4 EF-hand domain EF-hand_5 PF13202.6 EGR29296.1 - 7.3e-20 69.5 10.6 2.1e-05 23.8 0.4 4.7 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGR29296.1 - 2.2e-16 59.4 6.3 0.0051 16.6 0.1 4.6 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGR29296.1 - 2.1e-11 44.1 1.6 2.1e-06 28.0 0.4 2.4 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.6 EGR29296.1 - 0.00011 21.6 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR29296.1 - 0.00017 21.0 0.1 0.0003 20.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR29296.1 - 0.00092 19.2 0.1 0.0016 18.5 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGR29296.1 - 0.0063 15.3 0.0 0.012 14.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EGR29296.1 - 0.046 13.2 0.3 0.14 11.7 0.1 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Imm63 PF15599.6 EGR29296.1 - 0.047 14.1 0.3 12 6.4 0.1 2.7 2 0 0 2 2 2 0 Immunity protein 63 Dockerin_1 PF00404.18 EGR29296.1 - 0.048 13.9 5.2 14 5.9 0.3 4.2 2 2 1 3 3 3 0 Dockerin type I domain 7TMR-HDED PF07697.11 EGR29296.1 - 0.12 12.5 4.3 4.1 7.5 0.6 2.2 1 1 1 2 2 2 0 7TM-HD extracellular EF-hand_4 PF12763.7 EGR29296.1 - 0.29 11.1 4.9 6.4 6.8 0.0 3.2 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand GAGA_bind PF06217.12 EGR29297.1 - 1.1 9.5 21.8 2 8.6 21.8 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Kinesin PF00225.23 EGR29298.1 - 3.1e-98 328.8 0.6 3.1e-98 328.8 0.6 1.9 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EGR29298.1 - 1.2e-23 83.7 1.5 3.4e-23 82.2 0.2 2.5 2 0 0 2 2 2 1 Microtubule binding ZapB PF06005.12 EGR29298.1 - 0.16 12.4 0.2 0.16 12.4 0.2 4.5 3 1 1 4 4 4 0 Cell division protein ZapB SlyX PF04102.12 EGR29298.1 - 0.22 12.2 0.1 0.22 12.2 0.1 4.4 3 1 0 3 3 3 0 SlyX Kelch_6 PF13964.6 EGR29299.1 - 3.1e-27 93.9 8.8 2e-05 24.7 0.0 6.3 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.6 EGR29299.1 - 1.3e-26 92.1 11.6 1.6e-07 31.1 0.0 6.5 6 1 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 EGR29299.1 - 2.4e-24 85.0 8.0 1.1e-07 31.7 0.0 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 EGR29299.1 - 1.9e-22 79.0 0.0 3.1e-05 24.1 0.0 6.6 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.25 EGR29299.1 - 3.6e-21 74.5 5.2 0.0001 21.8 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EGR29299.1 - 1.5e-20 72.3 5.9 2.8e-05 23.9 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Pyr_redox_2 PF07992.14 EGR29300.1 - 1.3e-59 201.8 0.0 1.6e-59 201.6 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGR29300.1 - 1.5e-23 83.1 0.0 9.8e-23 80.5 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGR29300.1 - 7.8e-19 68.0 1.8 9.6e-16 58.1 0.0 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGR29300.1 - 1.3e-08 34.5 1.3 2.1e-06 27.2 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGR29300.1 - 2.2e-07 30.3 0.4 8.3e-05 21.8 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 EGR29300.1 - 5.7e-05 22.6 0.0 0.00017 21.1 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EGR29300.1 - 0.00018 20.9 0.3 0.0013 18.1 0.2 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 EGR29300.1 - 0.00022 20.4 0.8 0.00034 19.8 0.8 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 EGR29300.1 - 0.004 15.9 1.3 0.0053 15.5 0.5 1.6 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 EGR29300.1 - 0.0065 16.1 0.5 2.5 7.6 0.0 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 EGR29300.1 - 0.085 12.1 0.3 0.18 11.0 0.3 1.5 1 0 0 1 1 1 0 Thi4 family K_oxygenase PF13434.6 EGR29300.1 - 0.16 11.1 0.0 0.38 9.9 0.0 1.6 1 1 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EGR29300.1 - 2.6 8.3 7.4 1.2 9.4 2.5 2.4 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain Pkinase PF00069.25 EGR29301.1 - 1.4e-10 41.0 0.0 1.6e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29301.1 - 5.4e-05 22.6 0.0 7.4e-05 22.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Rhomboid PF01694.22 EGR29302.1 - 1.2e-31 109.7 14.4 1.2e-31 109.7 14.4 1.6 2 0 0 2 2 2 1 Rhomboid family DUF2417 PF10329.9 EGR29302.1 - 0.71 9.2 11.8 0.66 9.3 10.6 1.6 1 1 0 1 1 1 0 Region of unknown function (DUF2417) Pkinase PF00069.25 EGR29303.1 - 1.7e-66 224.3 2.5 1.7e-66 224.3 2.5 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29303.1 - 2.3e-42 145.1 0.8 2.3e-42 145.1 0.8 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR29303.1 - 3e-06 26.3 0.1 5.7e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase Tox-PLDMTX PF15645.6 EGR29303.1 - 0.035 14.4 1.4 0.16 12.3 1.4 2.1 1 0 0 1 1 1 0 Dermonecrotoxin of the Papain-like fold APH PF01636.23 EGR29303.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 EGR29304.1 - 2.2e-48 164.9 0.1 3.5e-48 164.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29304.1 - 6.4e-25 87.9 0.0 8.6e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR29304.1 - 1.4e-05 25.1 0.0 0.012 15.5 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EGR29304.1 - 0.0052 16.1 0.0 0.0089 15.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Peptidase_C31 PF05410.13 EGR29304.1 - 0.12 12.5 0.0 0.27 11.3 0.0 1.6 1 0 0 1 1 1 0 Porcine arterivirus-type cysteine proteinase alpha Pkinase_fungal PF17667.1 EGR29304.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase ACOX PF01756.19 EGR29306.1 - 2.7e-43 147.6 1.2 2.7e-43 147.6 1.2 2.3 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EGR29306.1 - 7.6e-21 75.0 1.1 7.6e-21 75.0 1.1 3.1 3 0 0 3 3 3 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 EGR29306.1 - 6.2e-13 48.8 0.0 1.2e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EGR29306.1 - 0.013 15.7 0.0 0.033 14.4 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, C-terminal domain WD40 PF00400.32 EGR29307.1 - 3.4e-21 75.1 10.4 6.2e-05 23.7 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Sof1 PF04158.14 EGR29307.1 - 6.6e-21 74.4 13.5 6.6e-21 74.4 13.5 1.7 2 0 0 2 2 2 1 Sof1-like domain ANAPC4_WD40 PF12894.7 EGR29307.1 - 3.8e-12 46.3 0.1 0.083 13.2 0.0 5.0 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGR29307.1 - 0.0071 16.4 0.1 31 4.7 0.0 3.9 2 1 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.6 EGR29307.1 - 0.19 12.2 1.0 56 4.4 0.0 3.7 4 0 0 4 4 4 0 PQQ-like domain DEAD PF00270.29 EGR29308.1 - 1.2e-39 135.9 0.5 1.2e-39 135.9 0.5 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR29308.1 - 5.5e-05 23.5 0.1 5.5e-05 23.5 0.1 3.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain SecA_DEAD PF07517.14 EGR29308.1 - 0.00084 18.7 1.1 0.00084 18.7 1.1 2.8 2 1 0 2 2 2 1 SecA DEAD-like domain Ectoine_synth PF06339.12 EGR29308.1 - 0.087 13.0 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 Ectoine synthase AAA_22 PF13401.6 EGR29308.1 - 6.1 7.1 7.6 5.3 7.3 1.5 3.3 2 1 0 2 2 2 0 AAA domain WD40 PF00400.32 EGR29309.1 - 1.2e-29 101.9 8.3 7.4e-06 26.6 0.0 6.6 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR29309.1 - 4.3e-15 55.8 2.8 0.00024 21.3 0.1 5.0 2 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGR29309.1 - 4.9e-05 22.8 0.1 0.0041 16.5 0.0 3.1 3 1 1 4 4 4 2 WD40-like domain Pyrid_ox_like PF16242.5 EGR29309.1 - 0.54 9.8 4.1 9.1 5.8 0.1 3.1 3 0 0 3 3 3 0 Pyridoxamine 5'-phosphate oxidase like DUF4215 PF13948.6 EGR29310.1 - 3.9e-06 27.2 17.7 3.9e-06 27.2 17.7 9.7 5 2 5 10 10 10 4 Domain of unknown function (DUF4215) Furin-like_2 PF15913.5 EGR29310.1 - 0.00072 19.7 86.5 0.0029 17.7 28.3 7.2 1 1 5 6 6 6 4 Furin-like repeat, cysteine-rich DUF956 PF06115.11 EGR29310.1 - 0.063 13.0 0.1 0.15 11.8 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF956) KAP PF05804.12 EGR29311.1 - 2.2e-92 310.4 27.3 2.9e-92 310.0 27.3 1.0 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) CHASE6_C PF17150.4 EGR29311.1 - 0.029 15.0 1.2 0.45 11.2 0.0 3.1 3 0 0 3 3 3 0 C-terminal domain of two-partite extracellular sensor domain Aminotran_1_2 PF00155.21 EGR29312.1 - 5.4e-41 141.0 0.0 6.2e-41 140.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGR29312.1 - 0.0014 18.0 0.0 0.002 17.5 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 EGR29312.1 - 0.0017 17.0 0.0 0.0023 16.6 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGR29312.1 - 0.0025 16.8 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGR29312.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Nramp PF01566.18 EGR29313.1 - 1.6e-105 353.0 14.7 1.6e-105 353.0 14.7 1.4 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein DUF2715 PF10895.8 EGR29313.1 - 0.067 12.8 0.8 0.13 11.9 0.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2715) Furin-like_2 PF15913.5 EGR29314.1 - 1.4e-14 54.2 171.4 2.8e-07 30.7 21.9 10.1 1 1 8 9 9 9 6 Furin-like repeat, cysteine-rich VSP PF03302.13 EGR29314.1 - 4.2e-07 29.2 133.7 0.00012 21.0 33.0 6.9 1 1 5 6 6 6 5 Giardia variant-specific surface protein Ribosomal_L7Ae PF01248.26 EGR29316.1 - 3.2e-21 74.9 0.2 3.6e-21 74.7 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Hydrolase_6 PF13344.6 EGR29316.1 - 0.0059 16.7 0.0 0.0071 16.4 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hep_core_N PF08290.11 EGR29316.1 - 0.17 11.9 0.3 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Hepatitis core protein, putative zinc finger RF-1 PF00472.20 EGR29317.1 - 2.5e-15 56.4 1.5 2.9e-15 56.2 0.2 1.7 1 1 1 2 2 2 1 RF-1 domain Pkinase PF00069.25 EGR29318.1 - 5.3e-60 203.0 0.0 1.2e-59 201.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 EGR29318.1 - 3.5e-38 129.6 0.2 7.9e-15 54.7 0.0 4.0 4 0 0 4 4 4 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 EGR29318.1 - 1.1e-28 100.2 0.1 3.3e-28 98.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29318.1 - 5.4e-06 25.9 0.0 1.7e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR29318.1 - 5.4e-05 22.2 0.1 9.3e-05 21.4 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR29318.1 - 0.00057 19.9 0.0 0.0022 17.9 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Cupin_2 PF07883.11 EGR29318.1 - 0.0057 16.3 0.1 2.7 7.8 0.0 3.3 3 0 0 3 3 3 1 Cupin domain TTL PF03133.15 EGR29319.1 - 5.6e-41 140.6 18.9 1.8e-22 79.8 7.3 2.1 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR29319.1 - 3.2e-08 33.1 12.5 1.4e-07 31.1 12.5 2.2 1 1 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR29319.1 - 2.6e-07 30.2 0.3 0.0068 15.7 0.1 2.4 2 1 0 2 2 2 2 Sugar-transfer associated ATP-grasp RdRP PF05183.12 EGR29319.1 - 0.054 12.1 4.8 0.078 11.6 4.8 1.2 1 0 0 1 1 1 0 RNA dependent RNA polymerase Linker_histone PF00538.19 EGR29319.1 - 0.11 12.9 3.3 0.18 12.2 0.5 2.6 1 1 1 2 2 2 0 linker histone H1 and H5 family HECW_N PF16562.5 EGR29321.1 - 0.012 15.4 0.6 0.039 13.8 0.6 1.9 1 0 0 1 1 1 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 I-set PF07679.16 EGR29321.1 - 0.034 14.2 0.4 0.078 13.1 0.4 1.6 1 0 0 1 1 1 0 Immunoglobulin I-set domain Furin-like_2 PF15913.5 EGR29321.1 - 0.35 11.0 76.2 0.44 10.7 25.7 5.8 1 1 4 5 5 5 0 Furin-like repeat, cysteine-rich Patatin PF01734.22 EGR29322.1 - 3.2e-17 63.4 0.0 4.5e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase Ion_trans_2 PF07885.16 EGR29323.1 - 2.2e-09 37.1 4.9 3.5e-09 36.5 4.9 1.3 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGR29323.1 - 3.7e-06 26.4 5.4 5e-06 25.9 5.4 1.2 1 0 0 1 1 1 1 Ion transport protein Fib_alpha PF08702.10 EGR29323.1 - 1.4 9.1 10.5 0.24 11.6 7.0 1.5 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Pkinase PF00069.25 EGR29324.1 - 1.5e-62 211.3 0.0 1e-61 208.6 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29324.1 - 6.6e-32 110.8 0.0 1.9e-18 66.7 0.0 2.0 2 0 0 2 2 2 2 Protein tyrosine kinase MCM PF00493.23 EGR29325.1 - 2.2e-98 327.8 1.6 4.3e-97 323.6 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EGR29325.1 - 1.1e-37 128.7 1.3 2.1e-37 127.8 1.3 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGR29325.1 - 1.7e-28 98.8 0.6 1.7e-28 98.8 0.6 2.2 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EGR29325.1 - 9.7e-15 55.0 2.2 4.5e-14 52.9 2.2 2.2 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGR29325.1 - 2.9e-05 23.5 0.0 0.00022 20.7 0.0 2.2 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGR29325.1 - 0.00011 22.3 0.0 0.00074 19.5 0.0 2.5 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGR29325.1 - 0.00083 19.2 0.0 0.003 17.4 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 EGR29325.1 - 0.094 13.4 0.1 4.2 8.1 0.0 2.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal Elf1 PF05129.13 EGR29325.1 - 0.35 10.9 3.1 0.87 9.7 3.1 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like UCH PF00443.29 EGR29326.1 - 3.6e-19 69.3 13.4 1.9e-12 47.3 2.4 2.5 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR29326.1 - 9.8 5.7 12.7 5.4 6.5 2.1 2.6 2 1 1 3 3 3 0 Ubiquitin carboxyl-terminal hydrolase Peptidase_M8 PF01457.16 EGR29329.1 - 7.6e-14 51.3 2.8 7.4e-10 38.1 1.6 2.5 2 1 0 2 2 2 2 Leishmanolysin Peptidase_M8 PF01457.16 EGR29330.1 - 1.8e-37 129.3 9.7 5.4e-32 111.2 0.3 2.6 2 1 1 3 3 3 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR29330.1 - 4.2e-05 23.5 6.2 4.2e-05 23.5 6.2 3.3 2 0 0 2 2 2 1 Tenascin EGF domain EGF_Tenascin PF18720.1 EGR29331.1 - 1.8e-07 31.0 7.1 1.8e-07 31.0 7.1 3.4 5 1 0 5 5 5 1 Tenascin EGF domain EGF_2 PF07974.13 EGR29331.1 - 0.00044 20.5 7.9 0.00044 20.5 7.9 4.5 3 1 1 4 4 4 1 EGF-like domain FMN_dh PF01070.18 EGR29332.1 - 4.7e-120 400.8 0.0 5.4e-120 400.6 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase IMPDH PF00478.25 EGR29332.1 - 1.2e-06 27.8 0.5 2.8e-06 26.6 0.4 2.0 1 1 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Glu_synthase PF01645.17 EGR29332.1 - 3.3e-06 26.5 0.0 9.1e-06 25.0 0.0 1.7 2 0 0 2 2 2 1 Conserved region in glutamate synthase His_biosynth PF00977.21 EGR29332.1 - 0.0061 16.1 0.4 0.046 13.2 0.0 2.5 3 1 0 3 3 3 1 Histidine biosynthesis protein ThiG PF05690.14 EGR29332.1 - 0.018 14.3 0.0 0.17 11.1 0.0 2.2 1 1 1 2 2 2 0 Thiazole biosynthesis protein ThiG Peptidase_S49 PF01343.18 EGR29332.1 - 0.023 14.7 0.1 0.047 13.6 0.1 1.5 1 0 0 1 1 1 0 Peptidase family S49 DHO_dh PF01180.21 EGR29332.1 - 0.03 13.5 0.2 2.2 7.4 0.0 2.3 1 1 1 2 2 2 0 Dihydroorotate dehydrogenase NMO PF03060.15 EGR29332.1 - 0.031 13.7 0.0 0.046 13.1 0.0 1.3 1 0 0 1 1 1 0 Nitronate monooxygenase UN_NPL4 PF11543.8 EGR29332.1 - 0.13 12.7 0.3 0.13 12.7 0.3 2.3 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 SAC3_GANP PF03399.16 EGR29333.1 - 2e-27 96.4 9.1 2.6e-25 89.4 9.1 2.1 1 1 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 EGR29333.1 - 1.2e-05 25.3 0.2 2.5e-05 24.3 0.2 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DUF2768 PF10966.8 EGR29334.1 - 4.8 7.7 13.3 2.1 8.9 3.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2768) Ras PF00071.22 EGR29335.1 - 9.8e-59 197.6 2.8 1.2e-58 197.3 2.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR29335.1 - 4.3e-35 120.5 0.2 4.3e-35 120.5 0.2 1.7 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR29335.1 - 2e-17 63.2 0.6 2.6e-17 62.8 0.6 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR29335.1 - 9.6e-08 32.1 0.1 2.2e-07 31.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGR29335.1 - 4.5e-07 29.9 1.5 0.017 15.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGR29335.1 - 1.3e-05 24.9 1.4 4e-05 23.2 0.6 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGR29335.1 - 2.5e-05 23.7 1.0 3.8e-05 23.2 1.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGR29335.1 - 0.00018 21.0 0.5 0.00033 20.1 0.5 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 EGR29335.1 - 0.0027 18.0 0.2 0.012 15.9 0.2 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGR29335.1 - 0.0043 17.4 0.0 0.009 16.4 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF3788 PF12663.7 EGR29335.1 - 0.016 15.2 0.1 4.6 7.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3788) DUF4783 PF16022.5 EGR29335.1 - 0.047 13.8 1.9 0.086 13.0 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4783) AAA_29 PF13555.6 EGR29335.1 - 0.1 12.3 0.1 0.25 11.1 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EGR29335.1 - 8.1 7.0 8.9 42 4.6 8.9 2.1 1 1 0 1 1 1 0 ABC transporter ABC_tran PF00005.27 EGR29336.1 - 1.1e-30 106.9 0.0 3.2e-30 105.4 0.0 1.9 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGR29336.1 - 7.6e-23 81.2 30.3 7.6e-23 81.2 30.3 1.9 2 1 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGR29336.1 - 5.2e-12 46.2 0.5 6.1e-08 32.8 0.0 2.8 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Dynamin_N PF00350.23 EGR29336.1 - 3.3e-05 24.0 0.0 0.00012 22.2 0.0 2.0 1 0 0 1 1 1 1 Dynamin family SMC_N PF02463.19 EGR29336.1 - 3.9e-05 23.2 0.9 0.00086 18.8 0.2 2.9 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGR29336.1 - 6.2e-05 23.0 0.0 0.00022 21.2 0.0 1.9 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EGR29336.1 - 0.0009 19.3 0.0 0.0047 17.0 0.0 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase IstB_IS21 PF01695.17 EGR29336.1 - 0.0033 17.2 0.0 0.8 9.4 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_29 PF13555.6 EGR29336.1 - 0.0038 16.9 0.0 0.0085 15.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 EGR29336.1 - 0.025 15.1 0.1 0.025 15.1 0.1 4.2 4 3 1 5 5 4 0 AAA domain SbcCD_C PF13558.6 EGR29336.1 - 0.032 14.5 0.1 0.39 11.0 0.0 2.5 2 1 0 2 2 1 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 EGR29336.1 - 0.1 11.9 0.0 0.24 10.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 EGR29336.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Rad51 PF08423.11 EGR29337.1 - 1.3e-126 421.1 0.1 1.9e-126 420.6 0.1 1.2 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EGR29337.1 - 9.7e-12 44.9 0.1 1.4e-11 44.4 0.1 1.2 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Pkinase PF00069.25 EGR29337.1 - 2.2e-10 40.4 0.1 3.9e-10 39.5 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain ATPase PF06745.13 EGR29337.1 - 3.1e-06 26.7 0.1 6.8e-06 25.6 0.1 1.6 1 1 0 1 1 1 1 KaiC AAA_25 PF13481.6 EGR29337.1 - 3.1e-05 23.6 0.0 5.2e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain Pkinase_Tyr PF07714.17 EGR29337.1 - 7.6e-05 22.1 0.0 0.00015 21.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PAXNEB PF05625.11 EGR29337.1 - 0.0023 17.1 0.1 0.0059 15.8 0.0 1.7 2 0 0 2 2 2 1 PAXNEB protein HHH_5 PF14520.6 EGR29337.1 - 0.0049 17.4 0.2 0.011 16.3 0.2 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain DnaB_C PF03796.15 EGR29337.1 - 0.081 12.2 0.4 1.4 8.2 0.4 2.4 1 1 0 1 1 1 0 DnaB-like helicase C terminal domain PDEase_I PF00233.19 EGR29338.1 - 1.1e-81 274.0 3.1 1.1e-81 274.0 3.1 2.2 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Ion_trans PF00520.31 EGR29338.1 - 1.1e-11 44.5 18.1 1.8e-11 43.7 18.1 1.4 1 0 0 1 1 1 1 Ion transport protein WD40 PF00400.32 EGR29339.1 - 1.4e-06 28.9 0.1 0.021 15.7 0.0 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR29339.1 - 0.0021 18.3 0.0 0.51 10.7 0.0 2.9 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Histone PF00125.24 EGR29340.1 - 1.4e-15 57.8 0.0 2.1e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EGR29340.1 - 2.1e-12 46.5 0.7 4.4e-12 45.5 0.7 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EGR29340.1 - 0.076 13.3 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone cNMP_binding PF00027.29 EGR29341.1 - 2.4e-36 123.6 0.2 2.8e-16 59.4 0.0 3.2 2 1 1 3 3 3 3 Cyclic nucleotide-binding domain Exo_endo_phos PF03372.23 EGR29342.1 - 4.6e-05 23.0 0.1 5.3e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF2303 PF10065.9 EGR29342.1 - 0.01 15.0 0.4 0.013 14.7 0.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) DUF423 PF04241.15 EGR29343.1 - 2.2e-13 50.2 0.1 3.1e-13 49.7 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Bax1-I PF01027.20 EGR29343.1 - 0.00048 20.0 0.8 0.00055 19.8 0.8 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Kinesin PF00225.23 EGR29344.1 - 2.1e-79 266.9 6.4 2.1e-79 266.9 6.4 2.3 2 1 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EGR29344.1 - 1.3e-07 31.7 24.4 1.7e-07 31.3 18.6 3.2 2 1 0 2 2 2 1 Microtubule binding AAA_22 PF13401.6 EGR29344.1 - 0.002 18.4 2.9 0.0097 16.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGR29344.1 - 0.058 13.8 0.0 0.13 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain NCD3G PF07562.14 EGR29345.1 - 0.22 11.5 12.5 0.021 14.8 4.1 2.6 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR LRR_6 PF13516.6 EGR29347.1 - 6.8e-06 25.7 12.3 3.7 7.9 0.1 7.2 7 0 0 7 7 7 3 Leucine Rich repeat LRR_1 PF00560.33 EGR29347.1 - 0.00038 20.6 10.0 3.1 8.7 0.0 6.8 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_8 PF13855.6 EGR29347.1 - 0.00041 20.1 19.5 0.01 15.5 5.2 5.5 4 1 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 EGR29347.1 - 0.41 11.2 28.2 0.2 12.1 3.2 5.6 4 1 3 7 7 7 0 Leucine Rich repeats (2 copies) Peptidase_C2 PF00648.21 EGR29348.1 - 3.2e-83 279.2 0.0 4.3e-83 278.7 0.0 1.2 1 0 0 1 1 1 1 Calpain family cysteine protease Pkinase PF00069.25 EGR29349.1 - 6.6e-63 212.5 0.6 8e-63 212.3 0.6 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29349.1 - 2e-39 135.5 0.1 2.6e-39 135.1 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR29349.1 - 7.1e-05 21.9 1.3 0.00011 21.3 0.1 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EGR29349.1 - 0.00071 19.0 0.0 0.00098 18.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR29349.1 - 0.036 12.8 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EGR29349.1 - 0.16 11.8 0.0 0.93 9.4 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family PNTB PF02233.16 EGR29350.1 - 2.7e-102 343.1 0.4 3.6e-102 342.7 0.4 1.2 1 0 0 1 1 1 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_N PF05222.15 EGR29350.1 - 1.3e-18 67.6 0.0 3.5e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.21 EGR29350.1 - 1.5e-18 66.9 0.1 3e-18 65.9 0.1 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 EGR29350.1 - 0.00024 20.5 1.1 0.017 14.5 0.7 2.9 2 1 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF4373 PF14297.6 EGR29350.1 - 0.094 13.5 1.4 0.29 11.9 0.3 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4373) Herpes_LMP1 PF05297.11 EGR29350.1 - 0.63 9.2 6.4 1.3 8.2 6.4 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) BaxI_1 PF12811.7 EGR29350.1 - 5.6 6.5 14.3 1.1 8.8 6.9 2.4 2 1 0 2 2 2 0 Bax inhibitor 1 like Arf PF00025.21 EGR29351.1 - 1.2e-61 207.2 2.8 1.4e-61 207.0 2.8 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGR29351.1 - 3.8e-15 56.2 0.4 6.3e-15 55.5 0.4 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGR29351.1 - 1.2e-14 54.2 0.5 1.4e-14 54.0 0.5 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGR29351.1 - 8.1e-12 45.0 0.5 1e-11 44.6 0.5 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGR29351.1 - 3e-11 43.1 0.3 3.8e-11 42.7 0.3 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGR29351.1 - 4.4e-10 39.3 4.4 8.4e-09 35.0 2.9 2.4 1 1 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 EGR29351.1 - 7e-08 32.5 0.2 1.2e-07 31.8 0.2 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGR29351.1 - 0.00059 19.4 0.8 0.027 14.0 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EGR29351.1 - 0.0053 16.8 0.0 0.31 11.1 0.1 2.3 2 0 0 2 2 2 1 Dynamin family cobW PF02492.19 EGR29351.1 - 0.02 14.5 0.9 0.16 11.5 0.2 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 EGR29351.1 - 0.17 11.9 2.5 4.6 7.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Methyltransf_31 PF13847.6 EGR29352.1 - 1.2e-05 25.2 0.0 1.3e-05 25.0 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGR29352.1 - 3.1e-05 24.6 0.0 3.5e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGR29352.1 - 0.00024 21.8 0.0 0.00026 21.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGR29352.1 - 0.00064 20.3 0.0 0.00071 20.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGR29352.1 - 0.0038 17.1 0.0 0.0045 16.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGR29352.1 - 0.038 13.7 0.0 0.043 13.6 0.0 1.1 1 0 0 1 1 1 0 Lysine methyltransferase Csm1_B PF18211.1 EGR29352.1 - 0.065 13.1 0.7 0.84 9.5 0.1 1.9 1 1 1 2 2 2 0 Csm1 subunit domain B Methyltransf_32 PF13679.6 EGR29352.1 - 0.067 13.2 0.0 0.069 13.1 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.19 EGR29352.1 - 0.073 12.8 0.0 0.08 12.7 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF1043 PF06295.12 EGR29352.1 - 0.081 12.9 0.1 0.1 12.6 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Na_H_Exchanger PF00999.21 EGR29354.1 - 1.2e-31 109.9 14.3 1.5e-31 109.6 14.3 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family adh_short PF00106.25 EGR29355.1 - 5.4e-45 153.2 6.3 8.6e-45 152.6 6.3 1.3 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGR29355.1 - 1.7e-42 145.6 3.8 6e-29 101.3 0.6 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGR29355.1 - 1.4e-09 38.1 1.7 3.7e-07 30.2 0.4 2.3 1 1 1 2 2 2 2 KR domain Epimerase PF01370.21 EGR29355.1 - 0.00044 19.8 0.7 0.0029 17.1 0.1 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EGR29355.1 - 0.0032 17.7 0.4 0.0082 16.4 0.1 1.8 1 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain GDP_Man_Dehyd PF16363.5 EGR29355.1 - 0.0062 16.0 0.5 0.017 14.5 0.1 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Rad17 PF03215.15 EGR29355.1 - 0.012 15.5 0.1 0.02 14.8 0.1 1.4 1 1 0 1 1 1 0 Rad17 P-loop domain RsgA_GTPase PF03193.16 EGR29355.1 - 0.02 14.8 0.1 0.064 13.2 0.1 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 EGR29355.1 - 0.12 13.0 0.1 0.22 12.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain DSPc PF00782.20 EGR29356.1 - 8.6e-22 77.4 0.1 1.4e-21 76.7 0.1 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGR29356.1 - 1.1e-05 25.1 0.1 1.4e-05 24.8 0.1 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase BacA PF02673.18 EGR29356.1 - 0.11 12.2 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Bacitracin resistance protein BacA PTPlike_phytase PF14566.6 EGR29356.1 - 0.13 12.4 0.0 0.25 11.5 0.0 1.3 1 1 0 1 1 1 0 Inositol hexakisphosphate Ion_trans_2 PF07885.16 EGR29357.1 - 5.7e-10 39.0 14.4 2e-09 37.3 14.4 1.8 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGR29357.1 - 6.2e-09 35.4 5.9 1.1e-08 34.7 5.9 1.3 1 0 0 1 1 1 1 Ion transport protein Lig_chan PF00060.26 EGR29357.1 - 0.00028 20.7 0.8 0.00041 20.2 0.8 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel Mito_carr PF00153.27 EGR29358.1 - 2.1e-51 171.8 1.9 3.9e-18 65.2 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGR29358.1 - 3.4e-05 23.1 0.5 0.59 9.2 0.0 3.1 2 1 1 3 3 3 3 Gammaproteobacterial serine protease Hydrolase_4 PF12146.8 EGR29360.1 - 0.023 14.0 0.1 3.1 7.0 0.1 2.2 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR29360.1 - 0.3 10.7 1.7 0.93 9.1 0.2 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold ELFV_dehydrog PF00208.21 EGR29361.1 - 1.4e-52 178.9 0.0 1.1e-51 175.9 0.0 2.0 1 1 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EGR29361.1 - 1.6e-52 176.8 0.0 4.2e-52 175.5 0.0 1.7 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Dynein_light PF01221.18 EGR29362.1 - 3.9e-30 104.0 0.4 4.4e-30 103.8 0.4 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Peptidase_M8 PF01457.16 EGR29363.1 - 7.8e-30 104.0 13.0 5.5e-27 94.7 1.1 2.2 1 1 1 2 2 2 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR29363.1 - 1e-05 25.4 10.6 1e-05 25.4 10.6 3.6 3 0 0 3 3 3 1 Tenascin EGF domain EGF_2 PF07974.13 EGR29363.1 - 0.0015 18.9 12.5 0.0015 18.9 12.5 4.9 5 0 0 5 5 5 1 EGF-like domain cEGF PF12662.7 EGR29363.1 - 0.033 14.1 0.3 0.033 14.1 0.3 4.2 3 1 0 3 3 3 0 Complement Clr-like EGF-like EGF_Tenascin PF18720.1 EGR29364.1 - 1.2e-05 25.2 9.5 1.2e-05 25.2 9.5 4.3 4 0 0 4 4 4 1 Tenascin EGF domain Furin-like_2 PF15913.5 EGR29364.1 - 0.0004 20.5 14.3 0.0004 20.5 14.3 6.4 1 1 4 6 6 6 1 Furin-like repeat, cysteine-rich DUF4215 PF13948.6 EGR29364.1 - 0.018 15.5 22.2 0.018 15.5 22.2 9.8 5 4 4 9 9 9 0 Domain of unknown function (DUF4215) EGF_2 PF07974.13 EGR29364.1 - 0.033 14.6 11.2 0.033 14.6 11.2 9.1 6 3 1 7 7 7 0 EGF-like domain Suv3_C_1 PF18147.1 EGR29364.1 - 0.07 13.0 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Suv3 C-terminal domain 1 PAS_9 PF13426.7 EGR29365.1 - 0.00032 20.9 0.2 0.00032 20.9 0.2 3.6 4 0 0 4 4 4 1 PAS domain PAS PF00989.25 EGR29365.1 - 0.048 13.7 0.0 0.17 11.9 0.0 1.9 1 0 0 1 1 1 0 PAS fold fn3 PF00041.21 EGR29366.1 - 0.1 12.9 1.9 4.2 7.8 0.0 3.2 3 0 0 3 3 3 0 Fibronectin type III domain tRNA-synt_1g PF09334.11 EGR29367.1 - 1.5e-18 66.7 0.3 1.6e-18 66.6 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (M) DUF3836 PF12930.7 EGR29367.1 - 0.0032 17.2 0.1 0.0057 16.4 0.1 1.4 1 1 0 1 1 1 1 Family of unknown function (DUF3836) HTH_56 PF18662.1 EGR29367.1 - 0.0047 17.0 2.5 0.0058 16.7 2.1 1.5 1 1 0 1 1 1 1 Cch helix turn helix domain Ferlin_C PF16165.5 EGR29367.1 - 0.12 12.3 1.4 0.14 12.1 1.4 1.2 1 0 0 1 1 1 0 Ferlin C-terminus Pkinase PF00069.25 EGR29368.1 - 2.1e-78 263.3 0.0 2.5e-78 263.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29368.1 - 1.2e-37 129.6 0.0 1.5e-37 129.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29368.1 - 0.00099 18.5 0.4 0.0048 16.3 0.0 1.9 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR29368.1 - 0.094 11.5 0.0 0.17 10.6 0.0 1.4 1 0 0 1 1 1 0 Fungal protein kinase zf-C3HC4_2 PF13923.6 EGR29369.1 - 5e-07 29.4 11.5 9.2e-07 28.6 11.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGR29369.1 - 1.8e-06 28.0 7.4 4e-06 26.9 7.4 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EGR29369.1 - 4.1e-06 26.6 11.0 8.4e-06 25.6 11.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGR29369.1 - 2.2e-05 24.2 9.3 3.4e-05 23.6 9.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EGR29369.1 - 5.5e-05 23.0 2.5 0.00013 21.7 2.5 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein DivIC PF04977.15 EGR29369.1 - 0.00012 21.8 11.0 0.3 10.9 8.8 2.4 1 1 1 2 2 2 2 Septum formation initiator zf-RING_UBOX PF13445.6 EGR29369.1 - 0.00032 20.7 10.9 0.00067 19.6 10.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGR29369.1 - 0.00034 20.9 9.1 0.00055 20.2 9.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGR29369.1 - 0.00035 20.5 11.1 0.0006 19.7 11.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain DUF3979 PF13141.6 EGR29369.1 - 0.011 16.0 2.0 0.016 15.4 1.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3979) HIP1_clath_bdg PF16515.5 EGR29369.1 - 0.022 15.4 8.3 0.022 15.4 8.3 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Prok-RING_4 PF14447.6 EGR29369.1 - 0.045 13.6 7.6 0.083 12.8 7.6 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 MAD PF05557.13 EGR29369.1 - 0.071 11.5 13.6 0.083 11.2 13.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein Exonuc_VII_L PF02601.15 EGR29369.1 - 0.13 11.8 5.1 0.14 11.7 5.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4201 PF13870.6 EGR29369.1 - 0.26 11.0 19.6 0.11 12.2 16.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DZR PF12773.7 EGR29369.1 - 0.45 10.6 9.1 1.5 8.9 9.1 1.8 1 1 0 1 1 1 0 Double zinc ribbon DUF2968 PF11180.8 EGR29369.1 - 0.54 9.9 9.8 0.92 9.1 9.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) Spc7 PF08317.11 EGR29369.1 - 0.55 9.1 18.1 0.45 9.3 16.7 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF641 PF04859.12 EGR29369.1 - 0.66 10.3 10.2 0.29 11.5 6.4 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) DUF724 PF05266.14 EGR29369.1 - 0.67 9.8 14.2 0.53 10.1 12.6 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF724) BLOC1_2 PF10046.9 EGR29369.1 - 0.94 9.8 15.1 1.6 9.1 7.2 2.6 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4140 PF13600.6 EGR29369.1 - 1.1 9.7 4.4 37 4.8 4.4 2.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.6 EGR29369.1 - 1.3 8.4 7.5 2.3 7.5 7.5 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 EGR29369.1 - 1.5 9.1 11.3 2.8 8.2 0.1 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 DUF848 PF05852.11 EGR29369.1 - 6.5 6.9 11.7 26 4.9 9.0 2.2 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) CRAL_TRIO PF00650.20 EGR29370.1 - 1.9e-16 60.2 4.7 4e-16 59.1 4.7 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGR29370.1 - 0.0003 20.9 1.6 0.0004 20.5 0.6 1.8 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain Pkinase PF00069.25 EGR29371.1 - 3.8e-68 229.7 0.4 4.7e-68 229.4 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29371.1 - 9.7e-38 129.9 0.0 1.4e-37 129.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 EGR29371.1 - 0.019 14.6 1.3 1.4 8.5 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGR29371.1 - 0.05 12.4 0.2 0.51 9.1 0.2 2.0 1 1 0 1 1 1 0 Fungal protein kinase PfkB PF00294.24 EGR29373.1 - 2.4e-35 122.3 0.0 3.2e-35 121.9 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EGR29373.1 - 0.00025 20.5 0.0 0.00053 19.4 0.0 1.5 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase PGI PF00342.19 EGR29374.1 - 1.6e-157 525.0 0.2 1.9e-157 524.8 0.2 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DER1 PF04511.15 EGR29375.1 - 0.0026 17.7 5.8 0.0026 17.7 5.8 1.4 1 1 0 1 1 1 1 Der1-like family ATP-grasp_6 PF18419.1 EGR29375.1 - 0.29 10.8 4.0 0.83 9.3 0.3 2.4 2 0 0 2 2 2 0 ATP-grasp-like domain Dynein_light PF01221.18 EGR29376.1 - 1.3e-42 144.0 2.0 1.4e-42 143.9 2.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 TMPIT PF07851.13 EGR29378.1 - 1.4 8.1 3.8 1.6 7.9 3.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein Chordopox_A30L PF06015.12 EGR29378.1 - 3.5 7.5 9.0 0.42 10.5 4.7 1.7 2 0 0 2 2 2 0 Chordopoxvirus A30L protein Kinesin PF00225.23 EGR29379.1 - 1.9e-44 152.0 2.2 2.8e-44 151.4 2.2 1.2 1 0 0 1 1 1 1 Kinesin motor domain Rhabdo_NV PF02484.15 EGR29379.1 - 0.023 14.8 1.1 52 4.1 0.0 3.9 4 0 0 4 4 4 0 Rhabdovirus Non-virion protein PCYCGC PF13798.6 EGR29379.1 - 0.034 14.0 0.2 0.052 13.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function with PCYCGC motif AAA_6 PF12774.7 EGR29380.1 - 2.6e-119 398.0 0.0 1.1e-118 396.0 0.0 2.1 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGR29380.1 - 7e-111 371.1 28.4 7e-111 371.1 28.4 3.7 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 EGR29380.1 - 0.00024 21.1 0.0 0.076 13.0 0.0 3.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EGR29380.1 - 0.0058 17.1 1.0 0.036 14.5 0.0 3.0 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGR29380.1 - 0.012 16.0 1.7 1.7 9.0 0.0 4.8 3 1 1 4 4 4 0 RNA helicase AAA_16 PF13191.6 EGR29380.1 - 0.07 13.5 2.1 6.5 7.1 0.0 3.5 4 0 0 4 4 4 0 AAA ATPase domain Glyco_trans_1_2 PF13524.6 EGR29380.1 - 0.15 12.5 0.4 1.7 9.1 0.0 3.0 3 0 0 3 3 3 0 Glycosyl transferases group 1 AAA_18 PF13238.6 EGR29380.1 - 0.47 11.0 0.0 0.47 11.0 0.0 4.1 4 1 0 4 4 4 0 AAA domain AAA_22 PF13401.6 EGR29380.1 - 1.5 9.1 4.6 7.2 6.9 0.0 3.8 3 1 0 3 3 3 0 AAA domain BBS2_C PF14782.6 EGR29382.1 - 6.8e-136 453.5 26.3 9.5e-136 453.0 26.3 1.2 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, C-terminal BBS2_Mid PF14783.6 EGR29382.1 - 3.1e-33 114.0 0.0 2.6e-32 111.0 0.0 2.7 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.6 EGR29382.1 - 1.3e-22 79.7 1.6 2.8e-22 78.6 0.2 2.4 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, N-terminal DUF4677 PF15726.5 EGR29382.1 - 0.015 15.5 0.2 0.027 14.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) VCBS PF13517.6 EGR29382.1 - 0.1 13.2 0.0 6 7.5 0.0 2.9 2 0 0 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella META PF03724.16 EGR29383.1 - 0.013 15.5 1.0 0.034 14.1 0.4 2.0 2 0 0 2 2 2 0 META domain Uteroglobin PF01099.17 EGR29383.1 - 0.029 14.7 5.5 0.079 13.3 1.5 3.0 2 1 0 2 2 2 0 Uteroglobin family Cas_GSU0053 PF09617.10 EGR29383.1 - 0.056 13.4 2.4 0.12 12.3 2.4 1.5 1 0 0 1 1 1 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) DUF5446 PF17522.2 EGR29383.1 - 0.088 13.0 6.7 0.079 13.1 3.6 2.7 2 1 0 2 2 2 0 Family of unknown function (DUF5446) DUF1664 PF07889.12 EGR29383.1 - 8.9 6.4 14.9 0.44 10.6 1.1 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) zf-C2H2_jaz PF12171.8 EGR29384.1 - 1.2e-07 31.8 0.2 3.4e-07 30.4 0.2 1.8 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGR29384.1 - 3.7e-06 27.2 0.9 3.7e-06 27.2 0.9 2.0 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-U1 PF06220.12 EGR29384.1 - 0.046 13.5 0.2 0.1 12.4 0.2 1.5 1 0 0 1 1 1 0 U1 zinc finger DUF2475 PF10629.9 EGR29386.1 - 3.2e-05 24.1 0.9 0.0031 17.7 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF2475) Pkinase PF00069.25 EGR29387.1 - 2.1e-33 115.8 0.0 2.3e-33 115.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29387.1 - 4.8e-18 65.4 0.0 5.1e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR29387.1 - 0.18 11.1 0.1 0.34 10.2 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGR29387.1 - 0.21 10.9 0.0 0.21 10.9 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Carb_anhydrase PF00194.21 EGR29388.1 - 2.1e-27 96.3 3.2 6.4e-27 94.7 3.2 1.7 1 1 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Packaging_FI PF14000.6 EGR29389.1 - 0.045 14.2 0.7 0.1 13.0 0.7 1.6 1 0 0 1 1 1 0 DNA packaging protein FI ApbE PF02424.15 EGR29389.1 - 0.092 12.3 0.3 0.18 11.3 0.3 1.4 1 0 0 1 1 1 0 ApbE family AcrZ PF10766.9 EGR29389.1 - 1.8 8.2 5.7 5.3 6.7 5.7 1.7 1 0 0 1 1 1 0 Multidrug efflux pump-associated protein AcrZ Syndecan PF01034.20 EGR29389.1 - 2.5 8.1 5.2 10 6.1 5.2 2.1 1 0 0 1 1 1 0 Syndecan domain EF-hand_1 PF00036.32 EGR29391.1 - 0.09 12.4 1.1 0.35 10.5 0.2 2.7 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 EGR29391.1 - 0.092 12.7 3.3 0.37 10.8 0.2 3.6 3 0 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.6 EGR29391.1 - 0.44 10.4 3.9 0.71 9.8 0.3 3.1 2 1 1 3 3 3 0 EF-hand domain pair RCC1 PF00415.18 EGR29393.1 - 1.8e-50 169.3 3.7 8.8e-10 39.1 0.0 6.5 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR29393.1 - 1.2e-35 120.5 10.6 1.8e-07 30.8 0.1 5.6 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat TIG PF01833.24 EGR29393.1 - 1.7e-09 37.6 1.8 7.7e-05 22.7 0.0 4.6 5 0 0 5 5 5 2 IPT/TIG domain YodL PF14191.6 EGR29393.1 - 0.015 16.1 0.7 0.32 11.9 0.1 2.7 2 0 0 2 2 2 0 YodL-like CX9C PF16860.5 EGR29394.1 - 0.0021 18.0 2.6 0.0021 18.0 2.6 2.3 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, DUF5010_C PF18099.1 EGR29394.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.6 1 1 0 1 1 1 0 DUF5010 C-terminal domain Pet191_N PF10203.9 EGR29394.1 - 0.15 12.4 3.2 6 7.2 0.1 2.2 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 MSL1_dimer PF16801.5 EGR29394.1 - 2.8 7.8 5.6 5.9 6.7 0.3 3.0 3 0 0 3 3 3 0 Dimerisation domain of Male-specific-Lethal 1 Pkinase PF00069.25 EGR29395.1 - 4.5e-66 222.9 1.0 4.5e-66 222.9 1.0 2.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29395.1 - 8.8e-36 123.5 0.1 1.8e-35 122.5 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase GpcrRhopsn4 PF10192.9 EGR29396.1 - 5.5e-06 26.0 1.8 7.4e-06 25.6 1.8 1.2 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain tRNA_anti_2 PF13742.6 EGR29396.1 - 0.071 13.3 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Metallophos PF00149.28 EGR29399.1 - 5e-09 37.0 0.1 9e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGR29399.1 - 0.00035 20.9 1.4 0.0018 18.6 1.4 2.2 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Dpy-30 PF05186.13 EGR29401.1 - 1.2e-08 34.5 0.2 2.5e-08 33.5 0.2 1.6 1 0 0 1 1 1 1 Dpy-30 motif ADK PF00406.22 EGR29401.1 - 1.5e-06 28.4 6.4 0.0017 18.5 0.6 3.4 4 0 0 4 4 4 2 Adenylate kinase AAA_17 PF13207.6 EGR29401.1 - 2.1e-06 28.2 4.1 0.00023 21.6 0.0 3.7 2 1 1 3 3 3 1 AAA domain AAA_28 PF13521.6 EGR29401.1 - 0.00041 20.6 0.0 0.0011 19.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain Hydin_ADK PF17213.3 EGR29401.1 - 0.00042 20.6 0.0 0.00042 20.6 0.0 3.5 4 1 1 5 5 5 1 Hydin Adenylate kinase-like domain SKI PF01202.22 EGR29401.1 - 0.00074 19.7 0.1 0.0065 16.6 0.0 2.7 2 0 0 2 2 2 1 Shikimate kinase AAA PF00004.29 EGR29401.1 - 0.0069 16.8 0.0 0.025 15.0 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGR29401.1 - 0.012 16.1 3.8 0.016 15.7 0.0 3.3 3 1 0 3 3 3 0 AAA domain IstB_IS21 PF01695.17 EGR29401.1 - 0.055 13.2 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 EGR29401.1 - 0.06 13.5 0.0 0.26 11.4 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGR29401.1 - 0.066 13.5 0.3 0.47 10.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain ECH_2 PF16113.5 EGR29402.1 - 2.4e-100 336.3 0.0 2.7e-100 336.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EGR29402.1 - 1.3e-19 70.5 0.6 1e-18 67.6 0.1 1.9 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Med23 PF11573.8 EGR29402.1 - 0.0047 14.7 1.9 0.0064 14.2 1.9 1.1 1 0 0 1 1 1 1 Mediator complex subunit 23 Nudix_hydro PF18290.1 EGR29402.1 - 0.88 9.6 2.8 2.3 8.3 0.4 2.4 2 0 0 2 2 2 0 Nudix hydrolase domain Kinesin PF00225.23 EGR29403.1 - 1e-81 274.5 2.5 1e-81 274.5 2.5 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGR29403.1 - 4e-12 46.3 0.3 4e-12 46.3 0.3 2.8 3 0 0 3 3 3 1 Microtubule binding GBP PF02263.19 EGR29405.1 - 1.2e-63 214.8 0.2 1.2e-63 214.8 0.2 8.8 6 1 6 12 12 12 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 EGR29405.1 - 1.6e-19 70.5 31.6 1.6e-19 70.5 31.6 12.0 2 1 10 12 12 12 1 Guanylate-binding protein, C-terminal domain MORN PF02493.20 EGR29406.1 - 1.3e-27 94.0 22.9 3.4e-05 23.5 0.5 7.1 7 0 0 7 7 7 7 MORN repeat SM-ATX PF14438.6 EGR29406.1 - 0.056 13.6 2.4 2.6 8.2 0.1 2.9 2 1 0 3 3 3 0 Ataxin 2 SM domain DUF523 PF04463.12 EGR29406.1 - 1.5 8.9 9.1 34 4.5 0.0 4.2 1 1 3 5 5 5 0 Protein of unknown function (DUF523) Kelch_6 PF13964.6 EGR29407.1 - 8.6e-06 25.9 0.4 0.0045 17.2 0.1 3.4 2 0 0 2 2 2 2 Kelch motif Pkinase_Tyr PF07714.17 EGR29407.1 - 0.0015 17.8 1.1 0.0028 17.0 1.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kelch_4 PF13418.6 EGR29407.1 - 0.079 13.0 0.2 3.1 7.9 0.0 2.7 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_1 PF01344.25 EGR29407.1 - 0.25 10.9 2.2 2 8.1 0.3 2.9 2 1 0 2 2 2 0 Kelch motif SHIPPO-rpt PF07004.12 EGR29408.1 - 1.6e-29 101.4 86.1 0.0024 18.7 0.2 12.7 12 0 0 12 12 12 12 Sperm-tail PG-rich repeat YtkA PF13115.6 EGR29408.1 - 0.059 14.0 3.7 34 5.1 0.0 4.8 6 1 1 7 7 7 0 YtkA-like CRAL_TRIO PF00650.20 EGR29409.1 - 2.6e-30 105.2 1.3 2.6e-30 105.2 1.3 2.2 3 0 0 3 3 3 1 CRAL/TRIO domain eIF-5_eIF-2B PF01873.17 EGR29409.1 - 3.1e-11 43.2 0.0 3.1e-11 43.2 0.0 3.2 3 0 0 3 3 3 1 Domain found in IF2B/IF5 Anoctamin PF04547.12 EGR29411.1 - 1.6e-07 30.5 7.0 1.6e-07 30.5 7.0 1.2 1 1 0 1 1 1 1 Calcium-activated chloride channel PHM7_cyt PF14703.6 EGR29411.1 - 0.00074 19.8 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Yip1 PF04893.17 EGR29411.1 - 0.0031 17.2 0.5 0.0055 16.4 0.5 1.3 1 1 0 1 1 1 1 Yip1 domain Solute_trans_a PF03619.16 EGR29411.1 - 0.0071 15.9 5.0 0.0098 15.4 5.0 1.3 1 0 0 1 1 1 1 Organic solute transporter Ostalpha RSN1_7TM PF02714.15 EGR29411.1 - 0.015 14.6 9.9 0.01 15.1 6.8 1.9 2 0 0 2 2 2 0 Calcium-dependent channel, 7TM region, putative phosphate Glucos_trans_II PF14264.6 EGR29411.1 - 0.052 12.9 8.5 0.081 12.3 8.4 1.4 1 1 0 1 1 1 0 Glucosyl transferase GtrII HisKA_4TM PF16926.5 EGR29411.1 - 0.081 12.5 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 Archaeal 4TM region of histidine kinase DUF2615 PF11027.8 EGR29412.1 - 0.14 12.3 1.5 0.17 12.0 1.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2615) CarboxypepD_reg PF13620.6 EGR29413.1 - 6e-31 106.6 0.0 0.00019 21.7 0.0 12.0 12 0 0 12 12 12 5 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 EGR29413.1 - 5.5e-09 35.9 39.4 0.011 15.7 0.9 11.6 11 1 1 12 12 12 3 CarboxypepD_reg-like domain Big_1 PF02369.16 EGR29413.1 - 6e-05 23.0 8.2 36 4.4 0.0 8.7 9 0 0 9 9 9 0 Bacterial Ig-like domain (group 1) Dioxygenase_C PF00775.21 EGR29413.1 - 0.0001 21.8 0.0 0.027 13.9 0.0 4.8 7 0 0 7 7 7 1 Dioxygenase MG2 PF01835.19 EGR29413.1 - 0.00081 19.8 1.5 5.3 7.6 0.0 5.2 4 0 0 4 4 4 1 MG2 domain SdrD_B PF17210.3 EGR29413.1 - 0.65 10.2 18.2 2 8.6 0.3 7.2 8 1 0 8 8 8 0 SdrD B-like domain MG4 PF17789.1 EGR29413.1 - 2.2 8.5 18.8 12 6.1 0.0 7.7 10 0 0 10 10 10 0 Macroglobulin domain MG4 RPA_interact_M PF14767.6 EGR29414.1 - 0.017 15.7 1.4 0.027 15.1 1.4 1.3 1 1 0 1 1 1 0 Replication protein A interacting middle EcsC PF12787.7 EGR29415.1 - 0.12 12.0 1.1 0.25 11.0 0.1 1.8 1 1 1 2 2 2 0 EcsC protein family COG2 PF06148.11 EGR29416.1 - 0.00074 19.6 8.8 0.00074 19.6 8.8 2.4 1 1 1 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF4407 PF14362.6 EGR29416.1 - 0.3 10.4 15.8 0.66 9.3 15.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 EGR29416.1 - 0.39 10.5 25.0 1.2 9.0 6.2 4.1 2 1 2 4 4 4 0 Septum formation initiator GvpL_GvpF PF06386.11 EGR29416.1 - 0.46 10.4 3.8 0.81 9.6 3.8 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF PRKG1_interact PF15898.5 EGR29416.1 - 0.77 10.7 20.7 0.12 13.3 15.1 2.2 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF948 PF06103.11 EGR29416.1 - 1.5 9.1 14.0 1.7 9.0 1.0 3.5 1 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) YtxH PF12732.7 EGR29416.1 - 2.2 8.9 5.0 4.5 7.9 3.2 2.5 2 1 0 2 2 2 0 YtxH-like protein DUF3450 PF11932.8 EGR29416.1 - 2.2 7.5 18.2 0.14 11.4 12.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) APG6_N PF17675.1 EGR29416.1 - 4.8 7.7 23.1 1.1 9.8 13.0 2.5 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF724 PF05266.14 EGR29416.1 - 6.8 6.5 22.3 8.3 6.2 7.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF724) PBP1_TM PF14812.6 EGR29417.1 - 0.46 10.9 8.0 0.33 11.3 7.1 1.4 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Metallophos PF00149.28 EGR29418.1 - 2.4e-32 113.1 0.7 3.1e-32 112.8 0.7 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGR29418.1 - 0.00028 21.3 0.1 0.00065 20.1 0.1 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain zinc_ribbon_5 PF13719.6 EGR29418.1 - 0.29 10.9 1.8 0.48 10.2 0.0 2.3 3 0 0 3 3 3 0 zinc-ribbon domain PIH1 PF08190.12 EGR29420.1 - 3.3e-34 117.8 2.0 3.3e-34 117.8 2.0 2.8 2 1 0 2 2 2 1 PIH1 N-terminal domain PIH1_CS PF18201.1 EGR29420.1 - 5.4e-24 84.5 0.8 1.3e-23 83.2 0.8 1.7 1 0 0 1 1 1 1 PIH1 CS-like domain AAA_23 PF13476.6 EGR29420.1 - 1 9.8 25.2 0.016 15.7 10.5 2.8 3 1 0 3 3 3 0 AAA domain Fibin PF15819.5 EGR29421.1 - 1.5 8.5 9.6 0.71 9.6 0.8 2.6 2 2 0 2 2 2 0 Fin bud initiation factor homologue Exo_endo_phos PF03372.23 EGR29422.1 - 1e-14 54.7 0.0 3e-14 53.1 0.0 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EGR29422.1 - 0.052 13.4 0.1 1.1 9.1 0.0 2.5 1 1 0 2 2 2 0 Endonuclease-reverse transcriptase Ras PF00071.22 EGR29423.1 - 1.2e-62 210.3 4.0 1.5e-62 210.0 4.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR29423.1 - 9.2e-36 122.7 2.0 9.2e-36 122.7 2.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR29423.1 - 1e-18 67.4 2.3 1.2e-18 67.1 2.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR29423.1 - 4.6e-07 29.9 0.3 7.9e-07 29.2 0.3 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGR29423.1 - 6.2e-07 29.0 1.2 7.6e-07 28.7 1.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGR29423.1 - 7.8e-05 22.3 1.3 0.00056 19.5 0.3 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGR29423.1 - 9e-05 22.0 0.1 0.00013 21.4 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EGR29423.1 - 0.00013 21.5 0.6 0.00044 19.8 0.6 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B ATPase_2 PF01637.18 EGR29423.1 - 0.0039 17.1 0.8 0.0057 16.6 0.5 1.5 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 EGR29423.1 - 0.02 14.8 0.8 0.73 9.7 0.3 2.2 1 1 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 EGR29423.1 - 0.028 13.9 0.1 0.059 12.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ATPase PF06745.13 EGR29423.1 - 0.042 13.2 0.4 0.35 10.2 0.0 2.1 1 1 1 2 2 2 0 KaiC TniB PF05621.11 EGR29423.1 - 0.044 13.2 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein MFS_1 PF07690.16 EGR29424.1 - 3.2e-35 121.7 13.0 3.2e-35 121.7 13.0 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGR29424.1 - 1.7e-05 23.9 28.6 0.0011 18.0 10.6 2.9 2 1 1 3 3 3 2 Sugar (and other) transporter SNF2_N PF00176.23 EGR29425.1 - 1.3e-49 168.8 0.5 3.4e-49 167.4 0.5 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGR29425.1 - 3e-18 66.2 0.4 3e-18 66.2 0.4 3.2 3 1 0 3 3 3 1 Helicase conserved C-terminal domain RlmM_FDX PF18125.1 EGR29426.1 - 0.62 10.6 7.8 4.2 7.9 0.4 3.1 2 1 1 3 3 3 0 RlmM ferredoxin-like domain RRM_1 PF00076.22 EGR29427.1 - 0.0072 16.1 0.0 0.02 14.7 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LPD24 PF18839.1 EGR29427.1 - 0.12 12.6 1.2 0.35 11.2 0.3 2.2 2 0 0 2 2 2 0 Large polyvalent protein associated domain 24 Ras PF00071.22 EGR29428.1 - 7.2e-57 191.5 1.2 1.2e-56 190.8 1.2 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR29428.1 - 4.5e-34 117.2 0.5 4.5e-34 117.2 0.5 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR29428.1 - 2.5e-17 62.9 2.7 2.7e-17 62.8 2.1 1.3 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGR29428.1 - 4.3e-08 32.8 3.0 8.8e-08 31.8 3.0 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGR29428.1 - 8.6e-05 22.0 1.8 0.00013 21.4 0.7 1.9 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGR29428.1 - 0.00011 22.2 0.2 0.0002 21.4 0.2 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGR29428.1 - 0.00018 21.4 1.2 0.36 10.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EGR29428.1 - 0.0019 18.5 0.4 0.026 14.8 0.1 2.5 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.9 EGR29428.1 - 0.003 17.3 0.9 0.033 13.9 0.9 2.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 EGR29428.1 - 0.0032 16.8 2.2 0.0052 16.1 0.1 2.3 2 1 0 2 2 2 1 Septin AAA_24 PF13479.6 EGR29428.1 - 0.015 15.1 0.4 0.029 14.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 EGR29428.1 - 0.021 14.8 5.0 0.049 13.6 5.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 EGR29428.1 - 0.045 13.3 1.1 0.06 12.9 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 EGR29428.1 - 0.058 13.8 0.2 0.16 12.4 0.1 1.8 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGR29428.1 - 0.093 12.7 0.2 0.34 10.9 0.0 1.9 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGR29428.1 - 0.11 12.9 0.3 0.31 11.4 0.3 1.9 1 1 0 1 1 1 0 AAA ATPase domain RNA_pol_Rpb2_7 PF04560.20 EGR29428.1 - 0.15 12.5 0.2 0.5 10.8 0.2 1.9 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 7 PIN_12 PF16289.5 EGR29428.1 - 1.4 9.4 12.7 0.059 13.9 5.8 2.0 1 1 1 2 2 2 0 PIN domain UCH PF00443.29 EGR29429.1 - 1.1e-33 116.9 4.9 1.1e-33 116.9 4.9 2.0 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EGR29429.1 - 9.6e-12 45.1 5.0 2.3e-11 43.9 5.0 1.6 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EGR29429.1 - 0.0028 17.3 3.8 0.0028 17.3 3.8 3.0 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Cytadhesin_P30 PF07271.11 EGR29429.1 - 3.2 7.2 5.3 4.9 6.6 5.3 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 RelE PF06296.12 EGR29429.1 - 5.9 7.0 9.0 16 5.6 9.0 1.7 1 0 0 1 1 1 0 RelE toxin of RelE / RelB toxin-antitoxin system ECH_1 PF00378.20 EGR29431.1 - 9.1e-38 130.0 0.2 1.4e-37 129.4 0.2 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGR29431.1 - 2.1e-23 83.4 0.0 1.3e-20 74.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PP2C PF00481.21 EGR29432.1 - 3.4e-41 141.6 0.1 4.9e-41 141.1 0.1 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PI3K_C2 PF00792.24 EGR29433.1 - 6.9e-07 29.3 0.1 0.00028 20.8 0.0 3.7 4 0 0 4 4 4 2 Phosphoinositide 3-kinase C2 His_Phos_1 PF00300.22 EGR29434.1 - 9.7e-32 110.2 0.0 1.2e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) LZ3wCH PF18517.1 EGR29435.1 - 3.2 7.9 7.6 1.2 9.3 0.2 2.9 3 0 0 3 3 3 0 Leucine zipper with capping helix domain Coatomer_WDAD PF04053.14 EGR29436.1 - 6e-110 368.3 27.7 2.4e-109 366.3 21.9 2.7 2 1 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 EGR29436.1 - 2.4e-32 110.5 8.4 4.1e-06 27.4 0.0 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR29436.1 - 3.8e-08 33.5 2.7 0.31 11.4 0.1 5.9 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGR29436.1 - 1.7e-07 31.3 0.7 0.042 13.9 0.1 5.1 5 0 0 5 5 5 2 Ciliary BBSome complex subunit 2, middle region HEPN_RES_NTD1 PF18870.1 EGR29436.1 - 0.0048 17.1 0.6 0.015 15.5 0.6 1.8 1 0 0 1 1 1 1 HEPN/RES N-terminal domain 1 FTA4 PF13093.6 EGR29436.1 - 0.12 12.2 1.4 0.27 11.1 0.1 2.1 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Fib_alpha PF08702.10 EGR29436.1 - 9.1 6.5 9.0 2.3 8.4 0.8 2.8 3 0 0 3 3 3 0 Fibrinogen alpha/beta chain family PHM7_cyt PF14703.6 EGR29437.1 - 0.16 12.1 0.1 0.22 11.7 0.1 1.2 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter dCMP_cyt_deam_1 PF00383.23 EGR29438.1 - 2.2e-23 82.0 2.1 3.6e-23 81.4 2.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGR29438.1 - 8.9e-13 48.2 0.5 8.9e-13 48.2 0.5 2.3 3 0 0 3 3 3 1 MafB19-like deaminase AAA_18 PF13238.6 EGR29438.1 - 0.0031 18.1 0.8 0.0031 18.1 0.8 2.2 1 1 1 2 2 2 1 AAA domain DUF1002 PF06207.11 EGR29438.1 - 1.7 8.1 6.7 3.9 6.9 6.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) Ribosom_S12_S23 PF00164.25 EGR29439.1 - 9.5e-46 154.1 0.1 1.2e-45 153.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 UCH PF00443.29 EGR29440.1 - 4.5e-43 147.6 46.5 4.5e-43 147.6 46.5 3.1 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EGR29440.1 - 1.4e-11 44.9 0.1 1.4e-11 44.9 0.1 7.3 4 3 0 4 4 4 1 DUSP domain UCH_1 PF13423.6 EGR29440.1 - 2e-11 44.1 52.7 8.3e-08 32.2 11.2 4.0 3 2 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase Exonuc_VII_L PF02601.15 EGR29440.1 - 5.5 6.5 18.3 5.4 6.5 7.6 2.9 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF1348 PF07080.11 EGR29441.1 - 1.6e-63 212.4 10.5 1.8e-63 212.2 10.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 EGR29441.1 - 0.0013 19.3 0.0 0.0018 18.9 0.0 1.3 1 1 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EGR29441.1 - 0.0075 16.7 0.0 0.0097 16.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) Transketolase_C PF02780.20 EGR29442.1 - 5.3e-44 149.1 0.0 1.2e-43 147.9 0.0 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 EGR29442.1 - 1.6e-42 145.2 0.0 2.3e-42 144.7 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain RINGv PF12906.7 EGR29443.1 - 1.5e-10 41.0 10.1 3.2e-10 40.0 10.1 1.6 1 0 0 1 1 1 1 RING-variant domain FHA PF00498.26 EGR29443.1 - 5.8e-09 36.2 11.3 7.7e-09 35.8 1.3 3.6 3 0 0 3 3 3 2 FHA domain Yop-YscD_cpl PF16697.5 EGR29443.1 - 5.8e-06 26.5 0.8 0.00042 20.6 0.1 3.2 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_2 PF13639.6 EGR29443.1 - 0.25 11.7 10.5 1.5 9.2 10.8 2.1 1 1 1 2 2 2 0 Ring finger domain FANCL_C PF11793.8 EGR29443.1 - 0.26 11.5 8.5 0.8 9.9 8.4 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain PNK3P PF08645.11 EGR29444.1 - 3.1e-54 183.1 0.5 3.1e-54 183.1 0.5 2.0 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase ABA_GPCR PF12430.8 EGR29444.1 - 5e-21 75.3 3.5 5e-21 75.3 3.5 2.2 3 0 0 3 3 3 1 Abscisic acid G-protein coupled receptor AAA_33 PF13671.6 EGR29444.1 - 3.5e-13 49.9 0.1 7.2e-11 42.4 0.1 2.5 1 1 0 1 1 1 1 AAA domain GPHR_N PF12537.8 EGR29444.1 - 1.5e-09 37.8 0.0 5.7e-09 35.9 0.0 2.0 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal Zeta_toxin PF06414.12 EGR29444.1 - 1.5e-07 30.9 0.2 0.0023 17.3 0.1 2.5 1 1 1 2 2 2 2 Zeta toxin T2SSE PF00437.20 EGR29444.1 - 0.0039 16.3 0.0 0.0072 15.4 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 EGR29444.1 - 0.0091 16.5 0.3 0.029 14.9 0.3 1.9 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 EGR29444.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EGR29444.1 - 0.014 15.8 0.1 0.58 10.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 EGR29444.1 - 0.028 14.7 0.0 0.081 13.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGR29444.1 - 0.071 13.4 0.0 0.17 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 EGR29444.1 - 0.084 12.8 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 FtsK_SpoIIIE PF01580.18 EGR29444.1 - 0.09 12.1 0.0 0.2 11.0 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 EGR29444.1 - 0.15 11.9 1.6 0.32 10.9 0.0 2.3 3 0 0 3 3 2 0 RsgA GTPase Pkinase PF00069.25 EGR29445.1 - 2.8e-40 138.4 4.3 7e-40 137.1 4.3 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29445.1 - 2.9e-26 92.3 1.9 1.6e-25 89.9 1.9 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29445.1 - 0.0013 18.1 1.8 0.0098 15.2 0.1 2.7 2 1 0 2 2 2 1 Kinase-like DUF1548 PF07579.11 EGR29445.1 - 0.023 15.1 2.2 0.023 15.1 2.2 2.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1548) DUF4200 PF13863.6 EGR29446.1 - 1.2e-16 61.2 20.4 1.2e-16 61.2 20.4 4.7 4 1 0 4 4 4 2 Domain of unknown function (DUF4200) Ras PF00071.22 EGR29448.1 - 5.3e-50 169.2 1.7 6.2e-50 169.0 1.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR29448.1 - 1.2e-32 112.7 0.7 1.5e-32 112.4 0.7 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR29448.1 - 2.1e-17 63.1 0.7 2.3e-17 63.0 0.7 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGR29448.1 - 1.5e-06 27.7 0.2 1.7e-06 27.5 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGR29448.1 - 3.5e-06 27.1 0.1 4.9e-06 26.6 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGR29448.1 - 0.00037 20.1 0.2 0.0012 18.4 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGR29448.1 - 0.00048 19.6 0.1 0.00058 19.3 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 EGR29448.1 - 0.0012 19.4 0.4 0.0019 18.7 0.4 1.3 1 1 0 1 1 1 1 ABC transporter AAA_7 PF12775.7 EGR29448.1 - 0.002 17.7 0.1 0.0061 16.1 0.0 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_22 PF13401.6 EGR29448.1 - 0.0024 18.1 0.1 0.059 13.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGR29448.1 - 0.0061 16.7 0.0 0.0077 16.4 0.0 1.1 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.18 EGR29448.1 - 0.0075 15.8 0.1 0.011 15.3 0.1 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_24 PF13479.6 EGR29448.1 - 0.0086 15.8 0.7 0.018 14.8 0.5 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGR29448.1 - 0.019 14.9 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EGR29448.1 - 0.035 13.8 0.0 0.083 12.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGR29448.1 - 0.084 12.8 0.5 0.52 10.2 0.1 2.2 1 1 1 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 EGR29448.1 - 0.15 12.5 0.0 0.2 12.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Myb_DNA-bind_6 PF13921.6 EGR29449.1 - 1.4e-23 82.9 11.1 2.8e-16 59.5 0.5 3.1 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGR29449.1 - 1.5e-21 76.3 6.5 2.3e-13 50.1 0.1 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGR29449.1 - 0.00025 20.9 1.1 0.0017 18.2 0.2 2.0 1 1 1 2 2 2 1 Myb DNA-binding like Rap1_C PF11626.8 EGR29449.1 - 0.00027 21.0 0.0 0.017 15.2 0.1 2.1 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain MRP-S26 PF14943.6 EGR29449.1 - 0.00088 19.2 0.1 0.0012 18.8 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ribosome subunit S26 SLIDE PF09111.10 EGR29449.1 - 0.0045 17.0 0.4 0.16 12.0 0.1 2.2 1 1 1 2 2 2 1 SLIDE SANT_DAMP1_like PF16282.5 EGR29449.1 - 0.031 14.5 0.6 0.94 9.7 0.1 2.2 1 1 1 2 2 2 0 SANT/Myb-like domain of DAMP1 WIYLD PF10440.9 EGR29449.1 - 0.036 13.9 0.2 0.098 12.5 0.1 1.7 2 0 0 2 2 2 0 Ubiquitin-binding WIYLD domain Skp1 PF01466.19 EGR29449.1 - 0.095 12.8 0.1 2.3 8.4 0.0 2.4 2 0 0 2 2 2 0 Skp1 family, dimerisation domain Acyltransferase PF01553.21 EGR29450.1 - 6.7e-11 41.9 0.0 6.5e-10 38.8 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase Staphostatin_B PF09023.10 EGR29451.1 - 0.00072 19.6 0.1 0.0013 18.8 0.1 1.4 1 0 0 1 1 1 1 Staphostatin B Sugar_tr PF00083.24 EGR29453.1 - 6.5e-24 84.6 7.1 8.2e-24 84.3 7.1 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGR29453.1 - 2.5e-12 46.4 7.9 2.9e-12 46.2 7.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_3 PF05977.13 EGR29453.1 - 0.11 10.9 0.1 0.15 10.4 0.1 1.1 1 0 0 1 1 1 0 Transmembrane secretion effector Fip1 PF05182.13 EGR29454.1 - 3.4e-12 45.7 0.8 3.4e-12 45.7 0.8 2.3 2 0 0 2 2 2 1 Fip1 motif PBP1_TM PF14812.6 EGR29454.1 - 0.02 15.3 2.1 0.02 15.3 2.1 1.7 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal UvrD-helicase PF00580.21 EGR29454.1 - 0.13 11.7 8.7 0.19 11.2 8.7 1.4 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain DUF3899 PF13038.6 EGR29454.1 - 2 9.0 4.5 2.9 8.5 2.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3899) DUF3270 PF11674.8 EGR29454.1 - 2.2 8.5 5.4 5.6 7.2 5.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) DUF4486 PF14858.6 EGR29455.1 - 1.6e-09 36.8 0.9 1.6e-09 36.8 0.9 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF4486) TPR_2 PF07719.17 EGR29455.1 - 0.0012 18.8 0.1 0.019 15.1 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGR29455.1 - 0.016 15.0 0.1 0.071 13.0 0.1 2.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Flu_C_NS1 PF03506.13 EGR29455.1 - 0.03 14.3 0.1 0.068 13.1 0.1 1.5 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) DUF913 PF06025.12 EGR29455.1 - 0.96 8.4 9.9 7.2 5.5 5.7 2.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) EOS1 PF12326.8 EGR29455.1 - 2 8.3 7.6 8.4 6.3 2.8 3.0 2 0 0 2 2 2 0 N-glycosylation protein Kei1 PF08552.11 EGR29455.1 - 2.6 7.9 9.2 8.7 6.2 0.0 2.5 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 5_nucleotid_C PF02872.18 EGR29458.1 - 4.3e-33 114.8 0.0 9.3e-33 113.7 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 EGR29458.1 - 1.2e-14 55.3 0.1 2.3e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ion_trans PF00520.31 EGR29459.1 - 1.1e-10 41.2 19.3 1.1e-05 24.9 7.1 3.3 3 1 0 3 3 3 3 Ion transport protein Hid1 PF12722.7 EGR29460.1 - 0.00017 19.9 23.4 0.00017 19.9 23.4 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Neur_chan_memb PF02932.16 EGR29460.1 - 0.022 14.8 16.9 0.028 14.5 16.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SDA1 PF05285.12 EGR29460.1 - 0.083 12.3 49.3 0.14 11.6 49.3 1.4 1 0 0 1 1 1 0 SDA1 DUF4045 PF13254.6 EGR29460.1 - 0.1 12.3 30.6 0.12 12.0 30.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) GAGA_bind PF06217.12 EGR29460.1 - 0.16 12.2 20.3 0.21 11.9 20.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Suf PF05843.14 EGR29460.1 - 0.28 11.1 24.8 0.39 10.7 24.8 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) BUD22 PF09073.10 EGR29460.1 - 0.3 10.4 43.5 0.38 10.0 43.5 1.2 1 0 0 1 1 1 0 BUD22 SAPS PF04499.15 EGR29460.1 - 0.39 9.4 28.9 0.63 8.8 28.9 1.5 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein GREB1 PF15782.5 EGR29460.1 - 0.53 7.3 26.8 0.59 7.2 26.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Asp-B-Hydro_N PF05279.11 EGR29460.1 - 0.87 9.6 50.5 1.1 9.3 50.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Smg8_Smg9 PF10220.9 EGR29460.1 - 1.8 6.8 29.4 2 6.7 29.4 1.1 1 0 0 1 1 1 0 Smg8_Smg9 Dapper PF15268.6 EGR29460.1 - 1.8 7.3 36.7 2.1 7.1 36.7 1.0 1 0 0 1 1 1 0 Dapper CDC45 PF02724.14 EGR29460.1 - 2.1 6.5 46.4 3 6.0 46.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SOBP PF15279.6 EGR29460.1 - 2.9 8.4 17.3 3.9 8.0 17.3 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein XRN_M PF17846.1 EGR29460.1 - 3 6.7 30.1 4 6.3 30.1 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Membralin PF09746.9 EGR29460.1 - 5.9 5.8 25.0 8 5.4 25.0 1.3 1 0 0 1 1 1 0 Tumour-associated protein DUF966 PF06136.13 EGR29460.1 - 8 6.1 29.2 9.3 5.9 29.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PAT1 PF09770.9 EGR29460.1 - 9.1 4.4 41.7 11 4.1 41.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CENP-F_leu_zip PF10473.9 EGR29461.1 - 0.0018 18.3 16.5 0.13 12.3 5.6 2.2 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 EGR29461.1 - 0.0021 18.6 10.1 0.0032 18.0 10.1 1.4 1 0 0 1 1 1 1 Apg6 coiled-coil region UPF0242 PF06785.11 EGR29461.1 - 0.013 15.7 10.1 0.016 15.3 10.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus AAA_13 PF13166.6 EGR29461.1 - 0.015 14.0 5.5 0.019 13.6 5.5 1.2 1 0 0 1 1 1 0 AAA domain HAP1_N PF04849.13 EGR29461.1 - 0.016 14.4 11.0 0.022 13.9 11.0 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region DUF1664 PF07889.12 EGR29461.1 - 0.016 15.2 9.2 0.034 14.2 5.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) SAM_KSR1 PF13543.6 EGR29461.1 - 0.018 15.2 2.6 0.018 15.2 2.6 1.9 1 1 1 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 GAS PF13851.6 EGR29461.1 - 0.019 14.3 14.1 2.2 7.6 2.2 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Helo_like_N PF17111.5 EGR29461.1 - 0.022 14.1 8.9 0.047 13.0 3.7 2.1 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins Sas6_CC PF18594.1 EGR29461.1 - 0.031 14.1 6.8 2.3 8.1 0.2 3.9 3 1 1 4 4 4 0 Sas6/XLF/XRCC4 coiled-coil domain HIP1_clath_bdg PF16515.5 EGR29461.1 - 0.041 14.5 8.8 0.041 14.5 8.8 2.2 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1708 PF08101.11 EGR29461.1 - 0.05 12.7 3.3 0.061 12.5 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1708) Spc7 PF08317.11 EGR29461.1 - 0.051 12.5 12.9 0.069 12.0 12.9 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4164 PF13747.6 EGR29461.1 - 0.076 13.3 9.0 0.065 13.5 5.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) ATG16 PF08614.11 EGR29461.1 - 0.083 13.1 12.9 1.1 9.4 2.0 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MRJP PF03022.16 EGR29461.1 - 0.087 12.2 0.8 0.11 11.9 0.8 1.2 1 0 0 1 1 1 0 Major royal jelly protein ZapD PF07072.11 EGR29461.1 - 0.1 12.4 6.9 0.13 12.0 6.9 1.3 1 0 0 1 1 1 0 Cell division protein DivIC PF04977.15 EGR29461.1 - 0.11 12.3 12.8 0.61 9.9 4.6 3.2 1 1 1 3 3 3 0 Septum formation initiator TPR_MLP1_2 PF07926.12 EGR29461.1 - 0.11 12.5 13.8 1.4 9.0 13.8 2.0 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4618 PF15397.6 EGR29461.1 - 0.12 11.8 12.6 0.17 11.2 12.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4618) Nnf1 PF03980.14 EGR29461.1 - 0.12 12.8 8.3 0.04 14.3 5.2 1.8 1 1 1 2 2 2 0 Nnf1 ADIP PF11559.8 EGR29461.1 - 0.12 12.4 15.4 0.75 9.9 7.1 2.6 1 1 2 3 3 3 0 Afadin- and alpha -actinin-Binding NRBF2 PF08961.10 EGR29461.1 - 0.14 11.7 7.4 0.13 11.8 5.7 1.5 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator DUF2968 PF11180.8 EGR29461.1 - 0.15 11.7 14.2 0.56 9.8 14.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Baculo_PEP_C PF04513.12 EGR29461.1 - 0.16 12.0 6.2 0.4 10.7 6.2 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus FapA PF03961.13 EGR29461.1 - 0.19 10.3 10.0 0.39 9.3 9.8 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A Cep57_MT_bd PF06657.13 EGR29461.1 - 0.21 12.1 12.9 1.6 9.2 4.5 2.3 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Jnk-SapK_ap_N PF09744.9 EGR29461.1 - 0.21 11.8 14.4 3.1 8.0 14.4 2.0 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 SKA2 PF16740.5 EGR29461.1 - 0.22 11.3 9.8 1.2 8.9 3.2 2.2 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 DUF4407 PF14362.6 EGR29461.1 - 0.22 10.8 7.2 0.34 10.2 7.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TLE_N PF03920.15 EGR29461.1 - 0.3 11.2 8.7 8.3 6.5 3.7 2.8 1 1 1 2 2 2 0 Groucho/TLE N-terminal Q-rich domain UCH PF00443.29 EGR29461.1 - 0.39 10.2 3.2 0.44 10.0 3.2 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase JIP_LZII PF16471.5 EGR29461.1 - 0.41 10.9 12.2 0.27 11.4 0.5 2.9 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II DUF5082 PF16888.5 EGR29461.1 - 0.47 10.7 10.8 0.45 10.8 2.7 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) bZIP_2 PF07716.15 EGR29461.1 - 1.3 9.1 13.4 0.13 12.4 1.5 3.4 1 1 1 3 3 3 0 Basic region leucine zipper ZapB PF06005.12 EGR29461.1 - 1.5 9.3 15.0 3.9e+02 1.6 14.8 2.6 1 1 0 1 1 1 0 Cell division protein ZapB Tho2 PF11262.8 EGR29461.1 - 1.8 7.7 9.8 3.5 6.7 9.8 1.6 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 DUF5320 PF17253.2 EGR29461.1 - 2 9.5 11.9 16 6.6 3.4 3.4 1 1 1 2 2 2 0 Family of unknown function (DUF5320) FAM76 PF16046.5 EGR29461.1 - 2.2 7.6 14.8 1.5 8.1 11.2 1.9 1 1 1 2 2 2 0 FAM76 protein HALZ PF02183.18 EGR29461.1 - 2.7 8.3 15.3 0.56 10.5 0.4 4.3 2 1 3 5 5 5 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 EGR29461.1 - 7 6.8 13.9 2.5 8.3 1.8 3.0 1 1 2 3 3 3 0 bZIP transcription factor TMPIT PF07851.13 EGR29461.1 - 7.3 5.7 10.0 2.4 7.3 5.3 1.8 1 1 1 2 2 2 0 TMPIT-like protein Spc24 PF08286.11 EGR29461.1 - 7.8 6.8 13.1 0.88 9.8 2.1 2.5 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 WD40 PF00400.32 EGR29462.1 - 2.6e-26 91.3 9.7 1.3e-05 25.8 0.1 6.6 6 0 0 6 6 6 6 WD domain, G-beta repeat WD40_like PF17005.5 EGR29462.1 - 0.0001 21.8 0.3 0.0001 21.8 0.3 2.9 3 1 0 4 4 4 2 WD40-like domain ANAPC4_WD40 PF12894.7 EGR29462.1 - 0.00039 20.7 0.1 0.02 15.2 0.0 3.2 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGR29462.1 - 0.0045 15.8 5.1 0.29 9.8 0.7 3.4 1 1 3 4 4 4 2 Nup133 N terminal like Peptidase_C2 PF00648.21 EGR29463.1 - 1.1e-13 50.9 0.3 1.7e-13 50.3 0.3 1.3 1 0 0 1 1 1 1 Calpain family cysteine protease Yip1 PF04893.17 EGR29463.1 - 1.6e-08 34.5 8.5 2.4e-08 33.9 8.5 1.2 1 0 0 1 1 1 1 Yip1 domain DUF1797 PF08796.10 EGR29463.1 - 0.4 10.8 0.1 0.4 10.8 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1797) Kinesin PF00225.23 EGR29464.1 - 1.7e-37 129.2 0.1 2e-37 128.9 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain 14-3-3 PF00244.20 EGR29467.1 - 3.6e-97 324.2 6.0 4.1e-97 324.0 6.0 1.0 1 0 0 1 1 1 1 14-3-3 protein ROS_MUCR PF05443.11 EGR29468.1 - 0.17 11.9 4.2 1.6 8.8 0.2 3.5 3 0 0 3 3 3 0 ROS/MUCR transcriptional regulator protein PEP_mutase PF13714.6 EGR29470.1 - 7.3e-64 215.5 0.0 1e-63 215.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EGR29470.1 - 0.00024 19.7 0.1 0.24 9.8 0.0 2.1 1 1 1 2 2 2 2 Isocitrate lyase family Phage_TAC_2 PF06894.11 EGR29470.1 - 0.018 14.9 0.9 0.049 13.4 0.2 2.0 3 0 0 3 3 3 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G FHA PF00498.26 EGR29471.1 - 1.7e-22 79.5 2.1 1.1e-11 44.9 0.2 2.6 2 0 0 2 2 2 2 FHA domain SAM_1 PF00536.30 EGR29471.1 - 5.2e-13 49.2 1.8 1.2e-12 48.1 1.8 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGR29471.1 - 2.1e-12 47.0 1.1 5.1e-12 45.7 1.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C3HC4_3 PF13920.6 EGR29471.1 - 7e-10 38.6 17.2 1.5e-09 37.6 17.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Yop-YscD_cpl PF16697.5 EGR29471.1 - 2.8e-09 37.2 0.0 0.00047 20.4 0.0 2.7 3 0 0 3 3 3 2 Inner membrane component of T3SS, cytoplasmic domain SAM_PNT PF02198.16 EGR29471.1 - 0.023 14.6 0.3 0.073 13.1 0.1 1.9 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain MU2_FHA PF18221.1 EGR29471.1 - 0.032 14.3 0.0 9.6 6.3 0.0 2.6 2 1 0 2 2 2 0 Mutator 2 Fork head associated domain FHA PF00498.26 EGR29473.1 - 3.4e-18 65.7 0.3 1.1e-07 32.1 0.0 2.7 2 0 0 2 2 2 2 FHA domain Yop-YscD_cpl PF16697.5 EGR29473.1 - 4.2e-12 46.2 0.0 4.3e-07 30.2 0.0 2.5 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_3 PF13920.6 EGR29473.1 - 1.2e-10 41.0 15.2 2e-10 40.3 15.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_2 PF07647.17 EGR29473.1 - 1.9e-07 31.1 0.7 0.0088 16.1 0.2 2.5 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGR29473.1 - 5e-07 30.1 0.7 0.0063 16.9 0.0 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) Arena_ncap_C PF17290.2 EGR29473.1 - 0.016 14.6 0.1 0.035 13.4 0.1 1.5 1 0 0 1 1 1 0 Arenavirus nucleocapsid C-terminal domain DUF483 PF04467.12 EGR29473.1 - 0.51 10.3 6.7 2.2 8.3 6.4 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF483) zf-RING_5 PF14634.6 EGR29473.1 - 2.2 8.3 17.7 5.3 7.1 17.7 1.8 1 0 0 1 1 1 0 zinc-RING finger domain MCM PF00493.23 EGR29474.1 - 1.4e-77 259.8 0.5 2.8e-77 258.8 0.2 1.6 1 1 1 2 2 2 1 MCM P-loop domain MCM_lid PF17855.1 EGR29474.1 - 3.3e-15 56.3 0.6 6.1e-15 55.4 0.6 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EGR29474.1 - 1.1e-10 41.3 0.4 2.9e-06 26.8 0.0 2.4 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGR29474.1 - 4.8e-09 36.3 0.0 1.6e-08 34.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGR29474.1 - 5e-05 23.2 0.0 0.00016 21.6 0.0 1.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGR29474.1 - 5.3e-05 23.0 0.2 0.00011 21.9 0.2 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_30 PF13604.6 EGR29474.1 - 0.00015 21.6 0.0 0.00032 20.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGR29474.1 - 0.00096 19.6 0.7 0.0025 18.2 0.1 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 EGR29474.1 - 0.0032 17.0 0.0 0.012 15.2 0.0 2.0 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 EGR29474.1 - 0.013 15.7 0.8 0.036 14.4 0.1 2.2 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGR29474.1 - 0.032 14.6 0.2 0.48 10.8 0.2 2.6 1 1 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 EGR29474.1 - 0.05 13.9 0.1 0.21 11.9 0.1 2.1 1 1 0 1 1 1 0 AAA domain AAA PF00004.29 EGR29474.1 - 0.052 14.0 0.2 0.17 12.3 0.2 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.25 EGR29475.1 - 7.2e-56 189.5 10.3 1.8e-54 184.9 10.3 2.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29475.1 - 1.6e-25 89.9 0.6 4.4e-25 88.4 0.6 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR29475.1 - 0.00059 19.2 0.2 0.0012 18.3 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR29475.1 - 0.022 13.5 0.1 0.039 12.7 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EGR29475.1 - 0.16 11.8 0.1 1 9.2 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Ank_4 PF13637.6 EGR29478.1 - 6.9e-15 55.2 7.2 1.2e-05 25.8 0.2 4.3 2 2 1 4 4 4 4 Ankyrin repeats (many copies) DHHC PF01529.20 EGR29478.1 - 1.3e-13 51.2 14.9 1.3e-13 51.2 14.9 3.3 3 1 0 3 3 3 1 DHHC palmitoyltransferase Ank_2 PF12796.7 EGR29478.1 - 1.2e-12 48.3 4.8 4.5e-06 27.2 1.8 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGR29478.1 - 1.6e-09 37.8 2.7 5.1e-07 29.9 0.4 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGR29478.1 - 1.1e-06 28.8 2.3 0.084 13.4 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EGR29478.1 - 4.7e-05 23.5 6.4 0.0036 17.7 0.2 5.4 5 0 0 5 5 5 1 Ankyrin repeat Fmp27_SW PF10305.9 EGR29478.1 - 0.063 14.0 3.6 0.99 10.2 0.6 2.7 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Pkinase PF00069.25 EGR29479.1 - 1.3e-66 224.7 0.0 3.6e-66 223.2 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29479.1 - 2e-36 125.6 0.0 5.1e-36 124.3 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 EGR29479.1 - 1.2e-20 73.5 0.1 1.9e-12 47.4 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGR29479.1 - 6.5e-20 71.5 0.1 1.2e-10 41.8 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGR29479.1 - 4.7e-18 65.0 0.0 7.4e-09 35.7 0.0 2.8 1 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR29479.1 - 1.8e-14 52.4 0.0 1.4e-05 25.1 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 EGR29479.1 - 4.2e-13 49.1 0.1 1.1e-05 25.7 0.0 4.0 3 0 0 3 3 3 3 Ankyrin repeat EHN PF06441.12 EGR29479.1 - 0.0071 16.7 0.0 7.2 7.0 0.0 3.2 2 0 0 2 2 2 2 Epoxide hydrolase N terminus Invas_SpaK PF03519.14 EGR29479.1 - 0.059 13.4 0.5 2 8.5 0.1 2.8 2 0 0 2 2 2 0 Invasion protein B family DUF2951 PF11166.8 EGR29480.1 - 0.17 12.1 1.5 0.54 10.5 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) Filamin PF00630.19 EGR29480.1 - 0.57 11.0 4.5 0.8 10.6 0.3 2.8 3 1 0 3 3 3 0 Filamin/ABP280 repeat DnaJ PF00226.31 EGR29481.1 - 1.8e-23 82.4 3.0 1.8e-23 82.4 3.0 3.2 4 0 0 4 4 4 1 DnaJ domain zf-C2H2_jaz PF12171.8 EGR29481.1 - 6.9e-08 32.6 3.5 2.9e-07 30.6 3.5 2.2 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGR29481.1 - 0.00022 21.5 1.9 0.00055 20.2 1.9 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EGR29481.1 - 0.0039 17.6 0.5 0.009 16.4 0.5 1.7 1 0 0 1 1 1 1 Zinc finger, C2H2 type RPT PF13446.6 EGR29481.1 - 0.036 14.0 0.1 0.16 11.9 0.1 2.3 1 1 0 1 1 1 0 A repeated domain in UCH-protein zf-C2H2_4 PF13894.6 EGR29481.1 - 0.049 14.5 0.2 0.16 12.9 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger zf_C2H2_ZHX PF18387.1 EGR29481.1 - 0.1 12.2 2.3 0.41 10.3 2.3 2.0 1 0 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain GDA1_CD39 PF01150.17 EGR29482.1 - 1.2e-48 165.9 9.1 4.1e-46 157.5 1.6 2.0 1 1 1 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family DUF948 PF06103.11 EGR29483.1 - 0.038 14.2 2.8 0.4 11.0 0.3 3.0 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ORC4_C PF14629.6 EGR29483.1 - 0.041 13.3 0.0 0.07 12.5 0.0 1.5 1 1 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus WXG100 PF06013.12 EGR29483.1 - 0.11 12.7 0.3 16 5.8 0.0 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG RPM2 PF08579.11 EGR29483.1 - 2.3 8.6 11.1 0.27 11.6 3.8 2.8 2 2 1 3 3 3 0 Mitochondrial ribonuclease P subunit (RPM2) PDEase_I PF00233.19 EGR29484.1 - 1.9e-44 152.1 16.7 1.9e-44 152.1 16.7 2.0 2 2 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Lipase_GDSL PF00657.22 EGR29484.1 - 6.1 6.8 7.7 3.8 7.4 2.9 2.9 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase Guanylate_cyc PF00211.20 EGR29486.1 - 4.3e-14 52.5 0.3 1.5e-13 50.8 0.3 1.8 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain DUF3910 PF13049.6 EGR29486.1 - 0.003 17.8 1.0 0.003 17.8 1.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF3910) Peptidase_M41 PF01434.18 EGR29487.1 - 3.6e-52 177.0 0.0 3.6e-52 177.0 0.0 2.1 2 1 0 2 2 1 1 Peptidase family M41 AAA PF00004.29 EGR29487.1 - 2.1e-43 147.9 0.3 9.4e-43 145.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGR29487.1 - 2.6e-13 49.5 0.1 7.5e-13 48.1 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain Cyclin_N PF00134.23 EGR29487.1 - 4.3e-11 42.7 0.1 1.4e-10 41.0 0.1 1.9 1 0 0 1 1 1 1 Cyclin, N-terminal domain TIP49 PF06068.13 EGR29487.1 - 8.7e-05 21.9 0.1 0.00066 19.0 0.0 2.3 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_16 PF13191.6 EGR29487.1 - 0.00087 19.7 0.4 0.0098 16.3 0.1 2.8 2 1 0 2 2 1 1 AAA ATPase domain RuvB_N PF05496.12 EGR29487.1 - 0.00097 18.9 0.0 0.0023 17.7 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain FtsH_ext PF06480.15 EGR29487.1 - 0.0016 18.7 1.8 0.007 16.7 1.8 2.1 1 0 0 1 1 1 1 FtsH Extracellular AAA_5 PF07728.14 EGR29487.1 - 0.0018 18.3 0.1 0.0086 16.1 0.0 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGR29487.1 - 0.0033 17.7 0.4 0.14 12.4 0.1 2.8 1 1 0 2 2 2 1 AAA domain DUF3295 PF11702.8 EGR29487.1 - 0.0035 16.8 14.1 0.0055 16.1 14.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3295) IstB_IS21 PF01695.17 EGR29487.1 - 0.014 15.1 0.0 0.041 13.6 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein Presenilin PF01080.17 EGR29487.1 - 0.032 13.0 19.7 0.059 12.1 19.7 1.4 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 EGR29487.1 - 0.043 14.0 13.5 0.11 12.6 13.5 1.7 1 0 0 1 1 1 0 DDHD domain Mg_chelatase PF01078.21 EGR29487.1 - 0.048 13.0 0.2 0.18 11.1 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Mem_trans PF03547.18 EGR29487.1 - 0.11 10.8 0.3 0.15 10.4 0.3 1.3 1 0 0 1 1 1 0 Membrane transport protein SLC12 PF03522.15 EGR29487.1 - 0.94 8.4 25.5 2.1 7.3 25.5 1.5 1 0 0 1 1 1 0 Solute carrier family 12 AAA_18 PF13238.6 EGR29487.1 - 1.1 9.9 0.0 1.1 9.9 0.0 3.8 3 1 0 3 3 2 0 AAA domain RR_TM4-6 PF06459.12 EGR29487.1 - 2.9 7.7 35.0 10 5.9 35.0 1.9 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Endostatin PF06482.11 EGR29487.1 - 3.9 6.9 15.1 6.9 6.0 15.1 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin NtCtMGAM_N PF16863.5 EGR29488.1 - 0.0023 18.1 1.6 0.0045 17.2 1.6 1.5 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase DUF4378 PF14309.6 EGR29489.1 - 0.0077 16.6 2.3 0.013 15.8 2.3 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4378) Nop10p PF04135.12 EGR29491.1 - 1.7e-17 63.1 0.1 4.1e-17 62.0 0.1 1.6 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family CCT PF06203.14 EGR29491.1 - 3.2e-06 27.1 2.7 6.5e-06 26.1 2.7 1.6 1 0 0 1 1 1 1 CCT motif ArfGap PF01412.18 EGR29492.1 - 6.3e-15 55.3 0.4 6.8e-15 55.2 0.4 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf zf_C2H2_ZHX PF18387.1 EGR29492.1 - 0.06 13.0 0.5 1.5 8.5 0.1 2.2 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain Rubredoxin_2 PF18073.1 EGR29492.1 - 0.12 12.1 1.8 1.2 8.9 0.2 2.1 2 0 0 2 2 2 0 Rubredoxin metal binding domain Nab2p_Zf1 PF18260.1 EGR29493.1 - 0.0093 15.8 1.2 0.34 10.9 0.2 2.4 2 0 0 2 2 2 2 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 N6_N4_Mtase PF01555.18 EGR29494.1 - 0.021 14.5 2.4 0.024 14.4 2.4 1.1 1 0 0 1 1 1 0 DNA methylase UFC1 PF08694.11 EGR29494.1 - 0.033 13.8 0.8 0.051 13.2 0.8 1.4 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Osteoregulin PF07175.11 EGR29494.1 - 0.042 14.0 3.6 0.061 13.5 3.6 1.2 1 0 0 1 1 1 0 Osteoregulin IL2 PF00715.17 EGR29494.1 - 0.066 13.1 1.8 0.089 12.7 1.8 1.3 1 0 0 1 1 1 0 Interleukin 2 Eaf7 PF07904.13 EGR29494.1 - 0.079 13.3 2.7 0.12 12.7 2.7 1.2 1 0 0 1 1 1 0 Chromatin modification-related protein EAF7 MORN PF02493.20 EGR29495.1 - 1e-52 173.0 68.2 1e-06 28.3 4.0 10.1 10 0 0 10 10 10 10 MORN repeat Tudor_2 PF18104.1 EGR29495.1 - 8.6 6.1 22.9 0.56 9.9 1.0 6.9 8 0 0 8 8 8 0 Jumonji domain-containing protein 2A Tudor domain Vps26 PF03643.15 EGR29496.1 - 4.6e-73 245.6 5.5 5.4e-73 245.4 5.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EGR29496.1 - 0.0031 17.6 1.1 0.081 13.0 0.1 2.7 2 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Pkinase PF00069.25 EGR29497.1 - 1.3e-70 237.8 1.9 1.3e-70 237.8 1.9 2.4 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29497.1 - 3.3e-37 128.2 0.2 3.3e-37 128.2 0.2 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29497.1 - 1e-08 34.9 0.0 1e-08 34.9 0.0 2.8 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 EGR29497.1 - 1.5e-05 24.0 1.9 0.00014 20.8 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EGR29498.1 - 2.8e-66 223.6 1.2 4.8e-66 222.8 1.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29498.1 - 1.5e-45 155.6 0.2 2e-45 155.1 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EGR29498.1 - 1.3e-10 41.5 3.1 4.3e-10 39.9 3.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGR29498.1 - 7.6e-08 31.4 7.7 7.9e-05 21.9 0.6 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EGR29498.1 - 1e-07 31.3 7.0 0.00089 19.0 0.2 3.5 3 0 0 3 3 3 2 EF-hand domain Pkinase_fungal PF17667.1 EGR29498.1 - 8.4e-07 28.1 0.0 1.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase EF-hand_8 PF13833.6 EGR29498.1 - 9.4e-06 25.4 2.5 0.0033 17.2 0.4 2.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGR29498.1 - 0.00013 21.3 1.2 0.31 10.6 0.1 3.0 2 0 0 2 2 2 2 EF hand ABC1 PF03109.16 EGR29498.1 - 0.0011 19.1 0.1 0.013 15.7 0.0 2.6 2 1 0 2 2 2 1 ABC1 family Kinase-like PF14531.6 EGR29498.1 - 0.0034 16.7 0.1 0.0034 16.7 0.1 2.9 2 1 1 3 3 3 1 Kinase-like SPARC_Ca_bdg PF10591.9 EGR29498.1 - 0.0037 17.6 5.6 0.0037 17.6 5.6 2.0 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.14 EGR29498.1 - 0.055 12.8 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_Treg PF04761.12 EGR29498.1 - 0.12 12.5 2.0 0.31 11.2 0.1 2.6 3 0 0 3 3 3 0 Lactococcus bacteriophage putative transcription regulator APH PF01636.23 EGR29498.1 - 0.19 11.6 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3337 PF11816.8 EGR29499.1 - 0.01 15.7 4.8 0.01 15.7 4.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3337) ECF_trnsprt PF12822.7 EGR29499.1 - 0.048 13.7 11.5 0.022 14.9 7.0 2.0 2 0 0 2 2 2 0 ECF transporter, substrate-specific component Comm PF15957.5 EGR29499.1 - 3.7 7.9 12.6 17 5.8 0.6 3.2 2 2 0 2 2 2 0 Commissureless Acetyltransf_1 PF00583.25 EGR29500.1 - 5.8e-18 65.2 0.1 9.2e-18 64.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGR29500.1 - 8.3e-12 45.2 0.5 1.5e-11 44.3 0.5 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGR29500.1 - 4.9e-11 42.9 0.3 9.1e-11 42.0 0.3 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGR29500.1 - 1.1e-06 28.9 3.6 2e-06 28.0 3.6 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGR29500.1 - 2.3e-05 24.3 0.2 4.2e-05 23.4 0.2 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EGR29500.1 - 5.1e-05 23.4 0.1 0.00013 22.1 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGR29500.1 - 0.00089 20.0 0.1 0.0013 19.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGR29500.1 - 0.011 15.5 0.1 0.035 13.8 0.0 1.8 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGR29500.1 - 0.077 13.1 0.2 0.19 11.9 0.0 1.8 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase eIF-3c_N PF05470.12 EGR29501.1 - 3.5e-69 233.7 50.5 7.4e-50 169.9 9.1 2.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EGR29501.1 - 0.0024 18.3 5.5 0.0024 18.3 5.5 3.8 3 1 0 3 3 3 1 PCI domain FRB_dom PF08771.11 EGR29501.1 - 1.8 9.0 7.1 2.4 8.6 2.2 3.5 2 1 0 2 2 2 0 FKBP12-rapamycin binding domain Cyclin_N PF00134.23 EGR29502.1 - 1.1e-37 128.7 0.4 1.1e-37 128.7 0.4 2.9 3 0 0 3 3 3 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGR29502.1 - 3.3e-14 53.0 0.1 3.3e-14 53.0 0.1 2.3 2 1 1 3 3 3 1 Cyclin, C-terminal domain Oxysterol_BP PF01237.18 EGR29503.1 - 6.2e-24 84.5 0.1 7.7e-24 84.2 0.1 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein EMC3_TMCO1 PF01956.16 EGR29504.1 - 0.098 12.4 0.1 0.098 12.4 0.1 5.3 3 1 1 4 4 4 0 Integral membrane protein EMC3/TMCO1-like MLANA PF14991.6 EGR29504.1 - 0.67 10.2 0.0 0.67 10.2 0.0 4.0 3 2 1 4 4 4 0 Protein melan-A SKICH PF17751.1 EGR29505.1 - 0.93 10.1 7.6 0.29 11.7 0.6 3.4 2 1 0 2 2 2 0 SKICH domain pRN1_helical PF13010.6 EGR29505.1 - 5.8 6.9 8.9 0.14 12.1 1.3 2.2 3 0 0 3 3 3 0 Primase helical domain EF-hand_1 PF00036.32 EGR29508.1 - 1.7e-13 49.1 0.4 2.7e-08 32.8 0.1 3.3 3 1 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EGR29508.1 - 4e-13 49.6 0.6 2.2e-10 40.9 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR29508.1 - 1.3e-09 37.2 0.1 1.2e-07 31.0 0.1 2.9 3 0 0 3 3 3 1 EF-hand domain EF-hand_8 PF13833.6 EGR29508.1 - 1.3e-08 34.5 2.2 3.3e-05 23.6 0.1 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGR29508.1 - 8.8e-07 28.1 0.2 7e-06 25.3 0.1 2.3 2 0 0 2 2 2 1 EF hand EF-hand_11 PF08976.11 EGR29508.1 - 8.6e-05 23.4 0.1 0.00047 21.0 0.0 1.8 1 1 1 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.10 EGR29508.1 - 0.0028 17.7 0.1 0.024 14.7 0.1 2.4 2 1 0 2 2 2 1 Ca2+ insensitive EF hand SUB1_ProdP9 PF18213.1 EGR29508.1 - 0.036 13.9 0.8 0.93 9.4 0.1 2.4 1 1 1 2 2 2 0 SUB1 protease Prodomain ProdP9 MotA_activ PF09114.10 EGR29508.1 - 0.067 13.3 0.0 0.092 12.9 0.0 1.3 1 1 0 1 1 1 0 Transcription factor MotA, activation domain CNOT1_TTP_bind PF16417.5 EGR29509.1 - 1.3e-57 194.0 8.8 1.3e-57 194.0 8.8 5.8 3 1 3 6 6 6 1 CCR4-NOT transcription complex subunit 1 TTP binding domain CNOT1_CAF1_bind PF16415.5 EGR29509.1 - 2.7e-57 193.8 22.3 2.7e-57 193.8 22.3 4.1 5 2 1 6 6 6 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain DUF3819 PF12842.7 EGR29509.1 - 1.7e-38 131.8 5.8 1.7e-38 131.8 5.8 5.2 3 1 1 4 4 4 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 EGR29509.1 - 5e-31 107.8 3.3 5e-31 107.8 3.3 6.8 4 1 0 4 4 4 1 CCR4-NOT transcription complex subunit 1 HEAT repeat Presenilin PF01080.17 EGR29509.1 - 0.013 14.3 38.4 0.029 13.2 38.4 1.6 1 0 0 1 1 1 0 Presenilin PNISR PF15996.5 EGR29509.1 - 0.25 11.6 45.9 0.77 10.0 45.9 1.8 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR CCSAP PF15748.5 EGR29509.1 - 6.6 6.8 40.1 14 5.8 40.1 1.6 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Dapper PF15268.6 EGR29509.1 - 7.4 5.3 49.1 12 4.6 49.1 1.2 1 0 0 1 1 1 0 Dapper Kelch_4 PF13418.6 EGR29511.1 - 2.6e-24 85.0 3.0 7.9e-06 25.8 0.1 5.3 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EGR29511.1 - 3.3e-23 81.2 1.2 3.4e-06 26.9 0.0 4.8 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 EGR29511.1 - 2.4e-17 62.5 3.3 2.6e-05 24.4 0.1 5.2 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 EGR29511.1 - 1.2e-16 60.0 1.6 0.00013 21.4 0.0 5.2 6 1 1 7 7 7 3 Kelch motif Kelch_2 PF07646.15 EGR29511.1 - 1.6e-13 50.0 1.3 0.0057 16.6 0.1 5.2 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.6 EGR29511.1 - 5.1e-13 49.0 0.1 0.012 15.9 0.0 6.0 6 0 0 6 6 6 2 Galactose oxidase, central domain LptF_LptG PF03739.14 EGR29511.1 - 0.022 13.6 8.1 0.041 12.7 8.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG DUF2238 PF09997.9 EGR29511.1 - 0.13 12.0 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2238) DUF2122 PF09895.9 EGR29511.1 - 0.25 11.7 1.8 1.1 9.7 0.3 2.6 3 0 0 3 3 3 0 RecB-family nuclease (DUF2122) Peptidase_S49_N PF08496.10 EGR29511.1 - 2.9 7.9 17.2 1.2 9.2 5.5 2.8 3 0 0 3 3 3 0 Peptidase family S49 N-terminal FAM60A PF15396.6 EGR29511.1 - 8.2 6.4 11.4 11 5.9 7.0 2.3 2 0 0 2 2 2 0 Protein Family FAM60A Dynein_light PF01221.18 EGR29513.1 - 3.3e-27 94.6 0.9 3.6e-27 94.5 0.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Tiam_CC_Ex PF18385.1 EGR29513.1 - 0.029 14.8 0.6 0.042 14.2 0.6 1.2 1 0 0 1 1 1 0 T-lymphoma invasion and metastasis CC-Ex domain Ureide_permease PF07168.11 EGR29514.1 - 0.00026 19.9 2.3 0.00026 19.9 2.3 4.2 5 1 0 5 5 5 1 Ureide permease PAS_9 PF13426.7 EGR29514.1 - 0.0017 18.6 0.0 0.02 15.1 0.0 3.0 1 0 0 1 1 1 1 PAS domain GDE_C PF06202.14 EGR29515.1 - 3.8e-111 371.7 0.2 3.8e-111 371.7 0.2 1.9 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hDGE_amylase PF14701.6 EGR29515.1 - 8.7e-103 344.7 4.5 8.7e-103 344.7 4.5 2.0 3 0 0 3 3 3 1 Glycogen debranching enzyme, glucanotransferase domain hGDE_central PF14702.6 EGR29515.1 - 1.7e-43 149.1 1.0 4.2e-43 147.8 1.0 1.6 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme AMPK1_CBM PF16561.5 EGR29515.1 - 1.5e-05 25.1 0.2 6.8e-05 23.0 0.2 2.1 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase Glyco_hydro_100 PF12899.7 EGR29515.1 - 0.011 14.5 8.1 0.23 10.1 0.2 3.6 4 0 0 4 4 4 0 Alkaline and neutral invertase Dynein_light PF01221.18 EGR29515.1 - 0.95 9.8 4.4 1.4 9.3 0.1 3.4 3 0 0 3 3 3 0 Dynein light chain type 1 putAbiC PF16872.5 EGR29515.1 - 3.4 8.4 7.4 10 6.9 2.7 3.0 2 0 0 2 2 2 0 Putative phage abortive infection protein Mito_carr PF00153.27 EGR29516.1 - 5e-06 26.3 0.2 0.0011 18.8 0.0 3.1 3 1 1 4 4 4 2 Mitochondrial carrier protein KASH_CCD PF14662.6 EGR29517.1 - 0.0022 17.9 20.9 0.003 17.4 20.9 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH TMF_DNA_bd PF12329.8 EGR29517.1 - 0.0037 17.2 17.5 0.094 12.7 8.8 3.1 2 1 1 3 3 3 2 TATA element modulatory factor 1 DNA binding DUF1732 PF08340.11 EGR29517.1 - 0.032 14.2 10.4 0.079 13.0 7.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1732) ZapB PF06005.12 EGR29517.1 - 0.038 14.4 26.2 0.2 12.1 12.5 3.1 1 1 2 3 3 3 0 Cell division protein ZapB YscO PF07321.12 EGR29517.1 - 0.12 12.3 18.3 0.16 11.9 8.6 2.8 1 1 2 3 3 3 0 Type III secretion protein YscO BRE1 PF08647.11 EGR29517.1 - 0.12 12.5 12.6 0.55 10.4 7.6 2.5 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Spc24 PF08286.11 EGR29517.1 - 0.16 12.2 13.3 52 4.1 12.6 2.6 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 YabA PF06156.13 EGR29517.1 - 0.16 12.6 16.8 1 10.1 11.5 2.9 1 1 1 2 2 2 0 Initiation control protein YabA TMF_TATA_bd PF12325.8 EGR29517.1 - 0.19 12.0 18.1 5.2 7.3 16.4 2.5 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding bZIP_1 PF00170.21 EGR29517.1 - 0.26 11.4 20.5 0.88 9.7 1.0 3.7 1 1 3 4 4 4 0 bZIP transcription factor Shugoshin_N PF07558.11 EGR29517.1 - 0.35 10.8 19.4 0.13 12.2 4.3 4.4 2 1 2 4 4 4 0 Shugoshin N-terminal coiled-coil region GAS PF13851.6 EGR29517.1 - 0.36 10.1 18.5 1.3 8.3 18.5 1.8 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF1192 PF06698.11 EGR29517.1 - 0.53 10.4 9.5 0.95 9.6 0.6 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1192) UPF0242 PF06785.11 EGR29517.1 - 0.71 10.0 19.4 2.7 8.0 10.4 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus BicD PF09730.9 EGR29517.1 - 1.2 7.5 18.5 1.5 7.2 18.5 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D ERM PF00769.19 EGR29517.1 - 1.4 8.7 13.0 7.9 6.2 11.8 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Atg14 PF10186.9 EGR29517.1 - 1.5 7.9 13.6 0.13 11.4 7.5 1.8 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Fzo_mitofusin PF04799.13 EGR29517.1 - 2.7 7.5 11.8 0.52 9.8 4.5 2.6 1 1 1 2 2 2 0 fzo-like conserved region TSC22 PF01166.18 EGR29517.1 - 2.7 8.4 19.6 0.34 11.2 5.3 3.5 1 1 3 4 4 4 0 TSC-22/dip/bun family Macoilin PF09726.9 EGR29517.1 - 2.9 6.3 10.8 12 4.4 10.8 1.9 1 1 0 1 1 1 0 Macoilin family DUF3450 PF11932.8 EGR29517.1 - 3.4 6.9 15.0 1.5 8.1 11.9 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.9 EGR29517.1 - 3.5 7.6 24.1 3.5 7.6 6.3 2.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2968 PF11180.8 EGR29517.1 - 4.7 6.8 13.7 0.78 9.4 9.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2968) FapA PF03961.13 EGR29517.1 - 5.8 5.4 8.2 6.5 5.2 8.2 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A bZIP_2 PF07716.15 EGR29517.1 - 8.1 6.6 24.0 5.7 7.1 6.4 4.4 1 1 3 4 4 4 0 Basic region leucine zipper Tropomyosin_1 PF12718.7 EGR29517.1 - 8.7 6.5 18.3 4 7.6 4.4 2.7 1 1 2 3 3 3 0 Tropomyosin like VPS13_C PF16909.5 EGR29518.1 - 3.2e-49 167.1 5.9 1.6e-43 148.5 1.3 3.1 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal WD40 PF00400.32 EGR29518.1 - 6.7e-33 112.2 12.9 0.011 16.5 0.0 17.8 18 0 0 18 18 18 6 WD domain, G-beta repeat HELP PF03451.14 EGR29518.1 - 4e-14 52.2 4.4 3.7e-05 23.5 0.1 4.6 4 0 0 4 4 4 2 HELP motif ATG_C PF09333.11 EGR29518.1 - 1.2e-08 35.1 0.0 4.5e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain ANAPC4_WD40 PF12894.7 EGR29518.1 - 1.1e-07 32.1 3.0 2.4 8.5 0.0 8.4 7 3 2 9 9 9 2 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_6 PF13405.6 EGR29518.1 - 0.012 15.5 4.2 0.094 12.7 0.1 3.5 2 0 0 2 2 2 0 EF-hand domain EF-hand_1 PF00036.32 EGR29518.1 - 0.28 10.8 2.6 0.26 10.9 0.1 2.4 2 0 0 2 2 2 0 EF hand EF-hand_7 PF13499.6 EGR29518.1 - 0.89 10.0 6.1 31 5.1 0.1 3.2 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_7 PF13499.6 EGR29519.1 - 0.001 19.5 1.4 0.12 12.9 0.3 1.8 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR29519.1 - 0.0028 17.1 0.1 0.056 13.0 0.1 2.8 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EGR29519.1 - 0.024 14.5 0.1 0.051 13.4 0.1 1.6 1 0 0 1 1 1 0 EF-hand domain pair Cyclin_N PF00134.23 EGR29520.1 - 9.4e-10 38.3 0.1 1.9e-09 37.4 0.1 1.5 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EGR29520.1 - 1e-07 32.4 0.1 1.7e-07 31.7 0.1 1.4 1 0 0 1 1 1 1 Cyclin His_Phos_1 PF00300.22 EGR29521.1 - 7.3e-37 127.0 0.1 1.4e-29 103.2 0.1 2.4 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) DUF4448 PF14610.6 EGR29521.1 - 1e-05 25.4 1.0 2.4e-05 24.2 1.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) UPF0449 PF15136.6 EGR29521.1 - 0.39 11.2 7.2 2.5 8.6 7.2 2.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 rve_2 PF13333.6 EGR29522.1 - 0.0046 17.1 0.6 0.12 12.6 0.1 2.4 2 0 0 2 2 2 1 Integrase core domain HIGH_NTase1_ass PF16581.5 EGR29522.1 - 0.016 15.2 0.7 0.021 14.8 0.7 1.2 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Pkinase PF00069.25 EGR29524.1 - 3.1e-30 105.4 0.1 5.6e-30 104.6 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29524.1 - 9.4e-19 67.7 0.0 1.4e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR29524.1 - 0.0024 17.8 0.0 0.0047 16.9 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR29524.1 - 0.0068 15.8 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGR29524.1 - 0.0079 15.8 0.2 0.0079 15.8 0.2 2.1 3 0 0 3 3 3 1 RIO1 family Kinase-like PF14531.6 EGR29524.1 - 0.021 14.1 0.4 0.047 13.0 0.0 1.7 2 0 0 2 2 2 0 Kinase-like ABC_tran PF00005.27 EGR29525.1 - 7.3e-29 101.0 0.2 1.4e-28 100.1 0.2 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGR29525.1 - 0.00069 19.1 2.1 0.0067 15.9 0.3 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EGR29525.1 - 0.0011 19.2 0.1 0.029 14.6 0.1 2.6 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_21 PF13304.6 EGR29525.1 - 0.0018 18.2 4.4 0.0041 17.0 0.1 2.2 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGR29525.1 - 0.014 15.3 2.1 0.027 14.4 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_29 PF13555.6 EGR29525.1 - 0.019 14.7 0.7 0.041 13.6 0.7 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EGR29525.1 - 0.096 12.2 0.5 6.5 6.3 0.2 2.8 2 1 1 3 3 3 0 AAA domain AAA_16 PF13191.6 EGR29525.1 - 0.13 12.7 0.1 0.23 11.9 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain HTH_46 PF15977.5 EGR29525.1 - 1.1 9.4 4.8 1.8 8.6 0.0 3.0 3 0 0 3 3 3 0 Winged helix-turn-helix DNA binding ABC_tran PF00005.27 EGR29526.1 - 6e-45 153.1 2.4 2.4e-25 89.7 0.1 3.9 5 0 0 5 5 4 2 ABC transporter ABC_membrane PF00664.23 EGR29526.1 - 2.5e-29 102.8 29.7 7.1e-23 81.6 23.6 2.6 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EGR29526.1 - 2.3e-09 37.0 26.0 9e-08 31.8 5.8 4.1 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGR29526.1 - 4.7e-07 29.9 8.9 0.25 11.1 0.0 5.0 3 2 2 5 5 5 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EGR29526.1 - 2.2e-06 27.7 0.4 0.1 12.7 0.1 3.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGR29526.1 - 2.6e-06 27.5 3.6 0.0039 17.1 0.7 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGR29526.1 - 4.5e-06 26.3 0.8 0.026 14.3 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EGR29526.1 - 4.5e-06 27.0 0.0 0.2 11.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGR29526.1 - 0.00015 22.1 2.1 0.73 10.3 0.0 4.3 4 0 0 4 4 3 2 RNA helicase T2SSE PF00437.20 EGR29526.1 - 0.0014 17.7 0.2 0.91 8.5 0.0 2.7 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_7 PF12775.7 EGR29526.1 - 0.0016 18.0 0.9 1.4 8.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_16 PF13191.6 EGR29526.1 - 0.0025 18.2 0.0 0.32 11.4 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain ATP-synt_ab PF00006.25 EGR29526.1 - 0.0074 16.0 0.8 3.2 7.3 0.1 2.9 2 1 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain cobW PF02492.19 EGR29526.1 - 0.0097 15.5 0.2 0.49 10.0 0.1 2.9 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.17 EGR29526.1 - 0.037 13.7 0.1 3.5 7.3 0.0 3.3 3 0 0 3 3 3 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.18 EGR29526.1 - 0.056 12.8 0.1 1.2 8.4 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family SbcCD_C PF13558.6 EGR29526.1 - 0.085 13.1 0.2 27 5.1 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EGR29526.1 - 0.086 12.5 0.1 2.2 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain DEAD PF00270.29 EGR29526.1 - 0.23 11.2 0.1 0.23 11.2 0.1 2.7 3 0 0 3 3 2 0 DEAD/DEAH box helicase NOA36 PF06524.12 EGR29526.1 - 0.86 8.9 5.9 2.3 7.5 5.9 1.7 1 0 0 1 1 1 0 NOA36 protein adh_short PF00106.25 EGR29528.1 - 7.5e-35 120.2 0.0 2.2e-28 99.0 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGR29528.1 - 5.1e-25 88.4 0.0 1.5e-22 80.4 0.0 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGR29528.1 - 3.7e-06 27.0 0.0 7e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGR29528.1 - 0.023 14.2 0.1 0.062 12.7 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family HEAT PF02985.22 EGR29529.1 - 2.2e-25 86.6 0.1 0.1 12.9 0.0 11.3 12 0 0 12 12 12 7 HEAT repeat HEAT_2 PF13646.6 EGR29529.1 - 5.8e-17 61.9 0.0 0.00042 20.7 0.0 6.6 4 2 1 6 6 6 3 HEAT repeats Vac14_Fab1_bd PF12755.7 EGR29529.1 - 3.2e-09 37.3 21.0 0.062 13.9 0.4 7.2 3 2 3 6 6 6 5 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EGR29529.1 - 6.1e-07 28.4 38.9 0.00028 19.6 0.7 3.5 2 1 1 3 3 3 2 Adaptin N terminal region RasGEF_N_2 PF14663.6 EGR29529.1 - 0.011 16.2 15.3 0.86 10.0 0.3 4.9 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain DNA_alkylation PF08713.11 EGR29529.1 - 0.011 15.5 3.0 5.5 6.6 0.0 4.1 3 1 0 4 4 4 0 DNA alkylation repair enzyme RTP1_C1 PF10363.9 EGR29529.1 - 0.23 11.7 16.0 3.8 7.7 0.5 5.2 2 2 4 6 6 6 0 Required for nuclear transport of RNA pol II C-terminus 1 Ion_trans PF00520.31 EGR29530.1 - 1.7e-16 60.2 19.6 1.7e-16 60.2 19.6 1.9 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 EGR29530.1 - 1.9e-11 43.8 1.6 1.9e-11 43.8 1.6 1.9 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 EGR29530.1 - 0.0067 16.5 0.0 0.012 15.6 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain zf-CCHC_4 PF14392.6 EGR29530.1 - 0.06 13.1 1.4 0.13 12.0 1.4 1.6 1 0 0 1 1 1 0 Zinc knuckle PTPlike_phytase PF14566.6 EGR29530.1 - 2.4 8.3 8.9 23 5.1 4.8 2.7 2 0 0 2 2 2 0 Inositol hexakisphosphate Pkinase PF00069.25 EGR29531.1 - 1.1e-26 93.8 2.0 2e-26 92.9 2.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29531.1 - 6.9e-17 61.6 0.4 1.1e-16 60.9 0.4 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ADH_zinc_N PF00107.26 EGR29531.1 - 4.1e-06 26.8 0.0 8.1e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGR29531.1 - 0.021 15.9 0.0 0.061 14.4 0.0 1.7 2 0 0 2 2 2 0 Zinc-binding dehydrogenase Pkinase PF00069.25 EGR29532.1 - 2.4e-74 250.0 1.8 2.4e-74 250.0 1.8 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29532.1 - 3.4e-46 157.6 0.1 3.4e-46 157.6 0.1 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29532.1 - 1.5e-05 24.4 0.3 1.5e-05 24.4 0.3 3.2 2 1 1 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 EGR29532.1 - 0.003 16.4 7.9 0.029 13.2 0.0 2.7 2 1 1 3 3 3 2 Fungal protein kinase APH PF01636.23 EGR29532.1 - 0.011 15.7 0.0 0.016 15.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DDHD PF02862.17 EGR29532.1 - 1.1 9.4 12.9 1.5 9.0 8.0 2.1 2 0 0 2 2 2 0 DDHD domain FCP1_C PF09309.10 EGR29532.1 - 6.2 6.6 9.4 6 6.7 5.4 2.0 2 0 0 2 2 2 0 FCP1, C-terminal UQ_con PF00179.26 EGR29533.1 - 2.3e-51 173.1 0.1 2.6e-51 172.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGR29533.1 - 2.7e-05 23.9 0.0 3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EGR29533.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain RWD PF05773.22 EGR29533.1 - 0.015 15.6 0.0 0.026 14.8 0.0 1.4 1 0 0 1 1 1 0 RWD domain G-gamma PF00631.22 EGR29533.1 - 0.13 12.3 0.1 0.13 12.3 0.1 1.7 2 0 0 2 2 2 0 GGL domain IMS PF00817.20 EGR29534.1 - 0.099 12.6 2.2 0.45 10.5 2.2 2.2 1 0 0 1 1 1 0 impB/mucB/samB family Ank_2 PF12796.7 EGR29535.1 - 6.5e-31 106.8 16.0 5.5e-10 39.7 0.7 3.9 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGR29535.1 - 1.9e-24 85.7 7.5 8.6e-09 35.8 0.3 4.6 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR29535.1 - 3.1e-24 82.4 0.7 0.00092 19.5 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 EGR29535.1 - 5e-20 71.3 1.0 5.7e-05 23.3 0.0 4.7 1 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EGR29535.1 - 1.4e-17 63.2 0.3 0.0086 16.5 0.0 5.6 5 1 0 5 5 5 5 Ankyrin repeat FBD PF08387.10 EGR29535.1 - 0.095 12.6 0.3 22 5.0 0.0 3.3 4 0 0 4 4 4 0 FBD PBD PF00786.28 EGR29536.1 - 2.4e-16 59.8 0.1 9.9e-13 48.2 0.0 2.9 2 1 1 3 3 3 2 P21-Rho-binding domain Pkinase PF00069.25 EGR29536.1 - 6.7e-08 32.2 0.0 1.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29536.1 - 0.00013 21.3 0.0 0.0002 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase MORN PF02493.20 EGR29537.1 - 2.2e-50 165.6 72.1 1.1e-07 31.3 0.4 10.3 11 0 0 11 11 11 10 MORN repeat Ribosomal_L5_C PF00673.21 EGR29538.1 - 2.6e-21 75.6 0.1 4.6e-21 74.8 0.1 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EGR29538.1 - 2.2e-19 69.5 0.0 3.7e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 EGR29538.1 - 0.0015 18.2 0.6 0.004 16.8 0.6 1.7 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain EF-hand_13 PF17958.1 EGR29539.1 - 0.054 13.3 0.1 10 6.0 0.0 2.9 2 0 0 2 2 2 0 EF-hand domain Furin-like_2 PF15913.5 EGR29539.1 - 0.73 10.0 99.8 0.057 13.6 13.0 7.1 2 2 3 6 6 6 0 Furin-like repeat, cysteine-rich VSP PF03302.13 EGR29539.1 - 2 7.2 93.3 0.011 14.6 16.8 5.2 1 1 3 4 4 4 0 Giardia variant-specific surface protein VSP PF03302.13 EGR29541.1 - 0.0049 15.8 20.8 0.0049 15.8 20.8 4.1 1 1 3 4 4 4 1 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EGR29541.1 - 1 9.5 86.8 0.19 11.9 25.6 5.5 1 1 3 4 4 4 0 Furin-like repeat, cysteine-rich Aldo_ket_red PF00248.21 EGR29542.1 - 8.4e-63 212.3 0.0 9.5e-63 212.1 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family KIP1 PF07765.12 EGR29542.1 - 0.00078 19.5 0.1 0.17 12.0 0.0 3.1 3 0 0 3 3 3 1 KIP1-like protein YdaS_antitoxin PF15943.5 EGR29542.1 - 0.011 15.6 0.6 0.044 13.7 0.5 2.2 1 1 1 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Sigma70_r4 PF04545.16 EGR29542.1 - 0.062 12.8 1.0 15 5.2 0.1 3.8 4 0 0 4 4 4 0 Sigma-70, region 4 HTH_3 PF01381.22 EGR29542.1 - 0.15 12.2 1.3 2.6 8.2 0.3 2.5 2 0 0 2 2 2 0 Helix-turn-helix DUF3611 PF12263.8 EGR29543.1 - 0.08 12.8 0.7 0.15 11.9 0.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3611) COPIIcoated_ERV PF07970.12 EGR29544.1 - 1.6e-37 129.5 4.5 2.7e-37 128.8 4.4 1.5 1 1 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGR29544.1 - 9e-28 96.5 0.1 2.6e-27 95.0 0.1 1.8 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PPL4 PF18188.1 EGR29544.1 - 0.014 15.3 0.1 0.035 14.0 0.1 1.7 1 0 0 1 1 1 0 Prim-pol 4 Rad17 PF03215.15 EGR29544.1 - 0.053 13.4 0.7 0.14 12.1 0.1 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain DUF778 PF05608.12 EGR29545.1 - 0.15 12.4 4.2 0.19 12.1 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF778) IZUMO PF15005.6 EGR29545.1 - 0.76 10.3 8.3 0.57 10.7 6.8 1.5 1 1 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated DUF1283 PF06932.11 EGR29545.1 - 2 8.7 7.8 0.4 10.9 3.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1283) Guanylate_cyc PF00211.20 EGR29546.1 - 3.3e-65 219.2 6.2 2.1e-46 157.8 1.4 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Lyase_1 PF00206.20 EGR29547.1 - 2.1e-113 378.8 0.1 3.2e-113 378.2 0.1 1.3 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EGR29547.1 - 6e-24 84.2 0.0 1.6e-23 82.9 0.0 1.8 1 0 0 1 1 1 1 Fumarase C C-terminus HsbA PF12296.8 EGR29547.1 - 0.072 13.5 0.6 1.9 9.0 0.1 2.8 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Guanylate_cyc PF00211.20 EGR29548.1 - 2.4e-84 281.5 2.5 7.9e-43 146.2 0.5 2.1 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain GFRP PF06399.13 EGR29548.1 - 0.13 12.2 0.0 2.1 8.3 0.0 2.8 3 0 0 3 3 3 0 GTP cyclohydrolase I feedback regulatory protein (GFRP) DUF382 PF04037.13 EGR29549.1 - 9.9e-52 174.4 0.8 9.9e-52 174.4 0.8 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 EGR29549.1 - 1.5e-19 69.6 1.6 2.9e-19 68.6 1.6 1.5 1 0 0 1 1 1 1 PSP PCI PF01399.27 EGR29550.1 - 0.00036 21.0 0.2 0.00059 20.3 0.1 1.4 2 0 0 2 2 2 1 PCI domain Dimerisation2 PF16864.5 EGR29550.1 - 0.016 15.2 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Dimerisation domain DUF2701 PF10857.8 EGR29550.1 - 0.14 12.2 0.9 1.7 8.8 0.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF2701) cNMP_binding PF00027.29 EGR29551.1 - 7.4e-15 54.8 0.0 1.3e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 EGR29551.1 - 8.1e-12 44.9 34.1 1.4e-11 44.2 34.1 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGR29551.1 - 1.4e-10 41.0 9.4 1.4e-10 41.0 9.4 2.3 2 1 0 2 2 2 1 Ion channel DUF3954 PF13128.6 EGR29551.1 - 0.15 11.9 0.1 0.43 10.4 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3954) DnaJ PF00226.31 EGR29552.1 - 0.00026 21.1 0.6 0.00026 21.1 0.6 1.7 2 0 0 2 2 2 1 DnaJ domain Dpy-30 PF05186.13 EGR29553.1 - 2.9e-12 46.0 0.2 8.5e-12 44.6 0.2 1.9 1 0 0 1 1 1 1 Dpy-30 motif Velvet PF11754.8 EGR29553.1 - 1.4 8.7 6.3 9.8 6.0 2.6 2.4 2 0 0 2 2 2 0 Velvet factor UPF0524 PF15823.5 EGR29553.1 - 1.7 8.0 11.2 0.28 10.5 0.3 2.6 2 0 0 2 2 2 0 UPF0524 of C3orf70 DUF913 PF06025.12 EGR29553.1 - 5.2 5.9 18.6 0.1 11.5 4.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) Slu7 PF11708.8 EGR29554.1 - 5e-07 29.7 6.6 5e-07 29.7 6.6 1.8 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 EGR29554.1 - 0.032 14.0 2.4 0.032 14.0 2.4 1.7 2 0 0 2 2 2 0 Zinc knuckle Cript PF10235.9 EGR29554.1 - 8.7 7.0 11.9 2 9.0 1.5 2.5 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Slu7 PF11708.8 EGR29555.1 - 1e-33 117.3 0.2 1e-33 117.3 0.2 2.0 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor Methyltransf_11 PF08241.12 EGR29556.1 - 3.2e-16 59.8 0.0 4.4e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGR29556.1 - 8.4e-16 58.5 0.0 1.3e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGR29556.1 - 8.9e-16 58.0 0.1 1.1e-15 57.8 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGR29556.1 - 4.4e-07 29.5 0.0 5.5e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGR29556.1 - 1.1e-06 29.3 0.0 1.8e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGR29556.1 - 2e-05 24.5 0.0 2.4e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 EGR29556.1 - 0.0024 17.0 0.0 0.0032 16.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Bin3 PF06859.12 EGR29556.1 - 0.097 13.3 0.3 17 6.1 0.1 2.2 1 1 1 2 2 2 0 Bicoid-interacting protein 3 (Bin3) CAMSAP_CKK PF08683.11 EGR29556.1 - 0.1 12.7 0.0 0.79 9.9 0.0 2.0 2 0 0 2 2 2 0 Microtubule-binding calmodulin-regulated spectrin-associated Methyltransf_PK PF05891.12 EGR29557.1 - 2.4e-63 213.6 2.4 9e-42 143.1 0.1 2.0 1 1 0 2 2 2 2 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 EGR29557.1 - 6.8e-10 39.5 0.0 1.3e-09 38.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGR29557.1 - 1.5e-06 28.7 0.0 2.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGR29557.1 - 1.2e-05 25.9 0.0 2.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGR29557.1 - 0.00081 19.0 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EGR29557.1 - 0.0011 18.8 0.1 0.0018 18.1 0.1 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGR29557.1 - 0.0016 18.3 0.0 0.0023 17.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EGR29557.1 - 0.0017 18.0 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) RrnaAD PF00398.20 EGR29557.1 - 0.0024 17.0 0.0 0.0034 16.5 0.0 1.4 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.7 EGR29557.1 - 0.013 15.5 0.0 0.045 13.7 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_2 PF00891.18 EGR29557.1 - 0.052 12.8 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain YppF PF14178.6 EGR29557.1 - 0.16 11.8 0.9 3.5 7.6 0.1 2.7 2 0 0 2 2 2 0 YppF-like protein MarR PF01047.22 EGR29560.1 - 0.06 13.3 0.2 0.99 9.4 0.1 2.4 2 0 0 2 2 2 0 MarR family ATP-synt_E_2 PF08112.11 EGR29560.1 - 0.41 11.0 5.1 0.38 11.1 1.3 2.7 2 0 0 2 2 2 0 ATP synthase epsilon subunit Pro_CA PF00484.19 EGR29562.1 - 1.4e-52 178.1 0.2 1.4e-52 178.1 0.2 2.0 2 1 0 2 2 2 1 Carbonic anhydrase 4HBT PF03061.22 EGR29563.1 - 2.9e-07 30.7 0.0 0.033 14.5 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily Transglut_core2 PF13369.6 EGR29563.1 - 0.087 12.4 0.1 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Transglutaminase-like superfamily Pkinase PF00069.25 EGR29564.1 - 6e-61 206.1 2.1 6e-61 206.1 2.1 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29564.1 - 9.5e-39 133.2 0.4 1.5e-38 132.6 0.4 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29564.1 - 4.1e-08 32.9 0.7 4.1e-08 32.9 0.7 1.9 2 1 1 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 EGR29564.1 - 1.4e-06 27.4 0.4 2.7e-06 26.4 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 EGR29564.1 - 0.00077 19.1 6.8 0.017 14.8 1.5 2.5 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGR29564.1 - 0.003 17.0 0.3 0.0049 16.2 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HEAT_EZ PF13513.6 EGR29565.1 - 0.0075 16.7 0.0 5 7.7 0.0 2.6 2 0 0 2 2 2 2 HEAT-like repeat Pkinase PF00069.25 EGR29566.1 - 1.1e-46 159.4 0.1 1.4e-46 159.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29566.1 - 2.7e-22 79.3 0.1 3.2e-22 79.0 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29566.1 - 3.5e-05 23.3 0.0 0.048 13.0 0.0 2.1 2 0 0 2 2 2 2 Kinase-like FTA2 PF13095.6 EGR29566.1 - 0.0001 22.0 0.2 0.0083 15.8 0.1 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EGR29566.1 - 0.0051 15.8 1.1 0.0067 15.4 1.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGR29566.1 - 0.14 12.0 0.0 1.1 9.1 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.32 EGR29567.1 - 3.7e-07 30.7 7.5 0.00071 20.3 0.0 5.5 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR29567.1 - 7e-07 29.5 1.3 0.72 10.2 0.0 4.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PD40 PF07676.12 EGR29567.1 - 0.0035 17.2 0.4 5.9 7.0 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat SRP_TPR_like PF17004.5 EGR29567.1 - 0.0057 16.7 1.5 0.0057 16.7 1.5 3.3 5 0 0 5 5 5 1 Putative TPR-like repeat TPR_12 PF13424.6 EGR29567.1 - 5.2 7.4 5.3 34 4.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGR29567.1 - 8.3 6.8 22.3 2 8.7 0.2 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat EAGR_box PF16713.5 EGR29567.1 - 9.6 6.0 6.6 5.1 6.9 0.3 2.8 2 0 0 2 2 2 0 Enriched in aromatic and glycine Residues box TTL PF03133.15 EGR29568.1 - 6.6e-28 97.7 22.7 3.5e-15 55.9 4.6 3.3 3 0 0 3 3 3 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR29568.1 - 4.2e-07 29.5 5.0 2.9e-06 26.7 0.0 3.2 2 2 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR29568.1 - 1.2e-05 24.8 1.7 0.0027 17.0 0.0 2.6 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp DUF4164 PF13747.6 EGR29570.1 - 0.0003 21.0 1.5 0.0003 21.0 1.5 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4164) Cep57_CLD_2 PF14197.6 EGR29570.1 - 0.0022 18.0 7.8 0.041 14.0 3.8 2.9 2 1 1 3 3 3 2 Centrosome localisation domain of PPC89 Sas6_CC PF18594.1 EGR29570.1 - 0.0025 17.5 5.0 0.58 10.0 0.6 3.4 3 0 0 3 3 3 2 Sas6/XLF/XRCC4 coiled-coil domain Vps23_core PF09454.10 EGR29570.1 - 0.0048 16.8 0.3 2.4 8.2 0.0 2.6 2 1 0 2 2 2 1 Vps23 core domain CENP-F_leu_zip PF10473.9 EGR29570.1 - 0.0096 15.9 11.2 0.059 13.4 9.6 2.1 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2968 PF11180.8 EGR29570.1 - 0.022 14.4 1.8 0.028 14.0 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) HIP1_clath_bdg PF16515.5 EGR29570.1 - 0.022 15.4 6.5 0.034 14.8 6.5 1.3 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SAM_KSR1 PF13543.6 EGR29570.1 - 0.046 13.9 4.3 0.097 12.8 2.7 2.2 1 1 1 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 Prominin PF05478.11 EGR29570.1 - 0.05 11.6 6.0 0.055 11.4 6.0 1.0 1 0 0 1 1 1 0 Prominin Cep57_MT_bd PF06657.13 EGR29570.1 - 0.092 13.2 5.1 1.7 9.1 0.8 2.4 1 1 2 3 3 3 0 Centrosome microtubule-binding domain of Cep57 DUF1664 PF07889.12 EGR29570.1 - 0.11 12.5 6.2 0.21 11.6 1.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Uso1_p115_C PF04871.13 EGR29570.1 - 0.14 12.6 10.0 0.87 10.0 10.0 1.9 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Atg14 PF10186.9 EGR29570.1 - 0.25 10.4 7.8 0.32 10.0 7.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SOGA PF11365.8 EGR29570.1 - 0.38 11.9 7.6 2.8 9.1 3.7 2.1 1 1 1 2 2 2 0 Protein SOGA APG6_N PF17675.1 EGR29570.1 - 0.59 10.7 7.7 1.8 9.1 7.7 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region DUF4140 PF13600.6 EGR29570.1 - 0.61 10.6 3.0 13 6.2 3.0 2.6 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Helo_like_N PF17111.5 EGR29570.1 - 0.67 9.3 6.9 1 8.7 5.8 1.7 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins FapA PF03961.13 EGR29570.1 - 0.73 8.4 10.2 1.2 7.7 10.2 1.4 1 1 0 1 1 1 0 Flagellar Assembly Protein A Ax_dynein_light PF10211.9 EGR29570.1 - 0.8 9.6 11.3 0.36 10.7 0.2 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain Baculo_PEP_C PF04513.12 EGR29570.1 - 1 9.4 8.7 4.8 7.2 8.7 1.9 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5320 PF17253.2 EGR29570.1 - 4.3 8.5 7.2 43 5.3 0.2 3.4 1 1 2 3 3 3 0 Family of unknown function (DUF5320) FlaC_arch PF05377.11 EGR29570.1 - 4.5 7.8 8.2 5.9 7.4 0.3 3.1 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) DUF2570 PF10828.8 EGR29570.1 - 4.9 7.0 9.0 16 5.3 0.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) TMPIT PF07851.13 EGR29570.1 - 6.5 5.9 8.2 22 4.1 8.2 1.8 1 1 0 1 1 1 0 TMPIT-like protein DivIC PF04977.15 EGR29570.1 - 7.8 6.4 9.7 0.62 9.9 1.0 2.4 1 1 2 3 3 3 0 Septum formation initiator ABC_tran_CTD PF16326.5 EGR29570.1 - 8.8 6.7 9.0 1e+02 3.3 5.4 3.0 1 1 1 2 2 2 0 ABC transporter C-terminal domain Pkinase PF00069.25 EGR29573.1 - 1.1e-65 221.6 0.0 1.1e-65 221.6 0.0 1.9 2 0 0 2 2 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29573.1 - 7.8e-41 140.1 1.1 9.1e-41 139.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Hydrolase_4 PF12146.8 EGR29573.1 - 4.1e-40 137.6 0.0 6.7e-40 136.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR29573.1 - 2e-10 40.7 0.3 4e-09 36.5 0.3 2.3 1 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGR29573.1 - 2.8e-06 28.1 0.0 4.3e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pkinase_fungal PF17667.1 EGR29573.1 - 1.1e-05 24.5 0.8 3.7e-05 22.7 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase Abhydrolase_5 PF12695.7 EGR29573.1 - 0.0021 17.9 1.1 0.075 12.8 0.0 2.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family APH PF01636.23 EGR29573.1 - 0.012 15.6 0.0 0.15 12.0 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Lipase_3 PF01764.25 EGR29573.1 - 0.021 14.7 0.0 0.083 12.7 0.0 2.0 1 0 0 1 1 1 0 Lipase (class 3) DLH PF01738.18 EGR29573.1 - 0.093 12.3 0.1 0.36 10.3 0.0 1.9 2 0 0 2 2 2 0 Dienelactone hydrolase family Thioesterase PF00975.20 EGR29573.1 - 0.11 12.6 0.1 0.22 11.6 0.1 1.4 1 0 0 1 1 1 0 Thioesterase domain 7TM_GPCR_Srab PF10292.9 EGR29574.1 - 0.073 12.0 0.3 0.15 11.0 0.3 1.4 1 0 0 1 1 1 0 Serpentine type 7TM GPCR receptor class ab chemoreceptor Sec20 PF03908.13 EGR29574.1 - 5.8 6.9 7.6 2.2 8.3 1.0 3.1 2 2 1 3 3 3 0 Sec20 Arm PF00514.23 EGR29575.1 - 0.0006 19.8 8.5 0.12 12.5 0.4 6.1 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat TRM PF02005.16 EGR29576.1 - 5.2e-89 299.0 2.1 6.7e-89 298.7 2.2 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Ubie_methyltran PF01209.18 EGR29576.1 - 0.0015 17.9 1.1 0.0033 16.8 1.1 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family zf-AN1 PF01428.16 EGR29576.1 - 0.44 10.7 3.3 12 6.1 0.7 2.5 2 0 0 2 2 2 0 AN1-like Zinc finger zf-ribbon_3 PF13248.6 EGR29576.1 - 0.62 9.6 6.3 2.2 7.8 1.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 EGR29576.1 - 3.8 7.3 5.1 5.6 6.8 0.3 2.5 2 0 0 2 2 2 0 Rubredoxin metal binding domain KOG2701 PF09762.9 EGR29576.1 - 6.1 7.0 11.4 1.7 8.9 6.4 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein (DUF2037) Prp19 PF08606.11 EGR29577.1 - 6.3e-29 99.8 1.5 8.9e-29 99.3 1.5 1.2 1 0 0 1 1 1 1 Prp19/Pso4-like zf-Nse PF11789.8 EGR29577.1 - 8.7e-07 28.7 0.1 2.3e-06 27.3 0.1 1.7 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.12 EGR29577.1 - 4.7e-05 22.9 0.0 0.014 14.8 0.0 2.3 1 1 1 2 2 2 2 Rtf2 RING-finger U-box PF04564.15 EGR29577.1 - 0.0002 21.5 0.1 0.00075 19.6 0.0 1.8 1 1 1 2 2 2 1 U-box domain zf-C3HC4_2 PF13923.6 EGR29577.1 - 0.0025 17.6 0.0 0.0042 16.9 0.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) VPS9 PF02204.18 EGR29577.1 - 0.0062 16.7 0.2 0.0091 16.2 0.2 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain zf-ANAPC11 PF12861.7 EGR29577.1 - 0.007 16.4 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EGR29577.1 - 0.019 15.0 0.0 0.06 13.4 0.0 1.8 1 1 1 2 2 2 0 RING-type zinc-finger zf-rbx1 PF12678.7 EGR29577.1 - 0.037 14.3 0.0 0.071 13.4 0.0 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain DiS_P_DiS PF06750.13 EGR29577.1 - 0.15 12.2 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial Peptidase A24 N-terminal domain Ca_bind_SSO6904 PF18249.1 EGR29578.1 - 0.057 13.8 0.4 0.19 12.1 0.3 1.9 2 0 0 2 2 2 0 Calcium binding protein SSO6904 Adenylsucc_synt PF00709.21 EGR29579.1 - 2.1e-171 570.5 0.0 2.4e-171 570.3 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase EF-hand_7 PF13499.6 EGR29580.1 - 5.8e-14 52.3 3.4 1.1e-08 35.4 0.2 2.9 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR29580.1 - 2.2e-12 45.9 3.0 0.00042 20.0 0.1 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 EGR29580.1 - 1.8e-10 39.6 3.1 0.032 13.8 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 EGR29580.1 - 9.2e-07 28.1 4.6 0.041 13.4 0.0 4.3 4 0 0 4 4 4 2 EF hand EF-hand_10 PF14788.6 EGR29580.1 - 2e-05 24.4 3.0 0.0086 15.9 0.0 3.6 3 1 1 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 EGR29580.1 - 0.025 14.9 0.5 0.19 12.1 0.3 2.5 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 EGR29580.1 - 0.043 13.7 0.7 7.5 6.5 0.0 3.1 2 1 1 3 3 3 0 EF-hand domain pair Caleosin PF05042.13 EGR29580.1 - 0.089 12.7 0.3 7.6 6.4 0.1 2.3 2 0 0 2 2 2 0 Caleosin related protein ARS2 PF04959.13 EGR29580.1 - 0.18 12.1 1.7 0.23 11.8 0.0 1.9 2 0 0 2 2 2 0 Arsenite-resistance protein 2 Dockerin_1 PF00404.18 EGR29580.1 - 1.1 9.5 8.5 17 5.7 2.8 3.4 3 1 1 4 4 4 0 Dockerin type I domain Pex14_N PF04695.13 EGR29581.1 - 2.9e-07 31.3 0.2 2.9e-07 31.3 0.2 1.8 1 1 1 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region LRR_8 PF13855.6 EGR29581.1 - 7.8e-05 22.4 7.2 0.00015 21.5 7.2 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 EGR29581.1 - 0.29 11.6 10.7 0.15 12.5 7.1 2.1 1 1 1 2 2 2 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGR29581.1 - 0.51 11.1 6.1 0.7 10.7 0.9 3.0 3 0 0 3 3 3 0 Leucine Rich Repeat TUDOR PF00567.24 EGR29582.1 - 5.3e-19 68.4 0.0 1.2e-18 67.3 0.0 1.6 1 0 0 1 1 1 1 Tudor domain SNase PF00565.17 EGR29582.1 - 9e-19 67.9 9.8 5.7e-11 42.8 3.1 4.1 3 1 0 3 3 3 3 Staphylococcal nuclease homologue STN1_2 PF09170.10 EGR29582.1 - 0.024 14.9 5.2 0.022 15.0 2.1 2.3 2 0 0 2 2 2 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 cNMP_binding PF00027.29 EGR29583.1 - 3.8e-08 33.3 0.0 7.3e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain AhpC-TSA PF00578.21 EGR29584.1 - 4.7e-33 113.7 0.0 6.8e-33 113.2 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGR29584.1 - 5.8e-16 58.5 0.0 8e-16 58.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EGR29584.1 - 2.3e-10 40.1 0.3 4.4e-10 39.2 0.3 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 EGR29584.1 - 0.043 13.7 0.2 0.086 12.8 0.1 1.5 2 0 0 2 2 2 0 SCO1/SenC WD40 PF00400.32 EGR29585.1 - 1.8e-24 85.5 9.0 7.7e-05 23.4 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR29585.1 - 3.6e-11 43.2 0.2 0.03 14.6 0.0 5.9 1 1 6 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain Takusan PF04822.13 EGR29585.1 - 0.74 9.7 25.7 1.2 9.0 9.1 2.8 1 1 0 2 2 2 0 Takusan Ank_4 PF13637.6 EGR29586.1 - 4.6e-14 52.6 0.5 2e-07 31.4 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGR29586.1 - 1.5e-07 31.5 0.0 3.3e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeat Ank_5 PF13857.6 EGR29586.1 - 5.7e-06 26.5 0.0 1.1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGR29586.1 - 1.3e-05 25.7 0.3 2.2e-05 24.9 0.3 1.3 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGR29586.1 - 4.9e-05 23.4 0.0 0.0001 22.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeat Peptidase_M8 PF01457.16 EGR29587.1 - 8.9e-21 74.2 0.0 1.4e-20 73.5 0.0 1.3 1 1 0 1 1 1 1 Leishmanolysin DUF5033 PF16436.5 EGR29587.1 - 0.0049 16.9 0.0 0.0061 16.5 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF5033) Ribosomal_L13 PF00572.18 EGR29588.1 - 7.3e-09 35.9 0.1 1.7e-06 28.3 0.0 2.9 1 1 1 2 2 2 1 Ribosomal protein L13 GGACT PF06094.12 EGR29588.1 - 0.042 14.5 0.0 0.14 12.8 0.0 2.1 1 1 0 1 1 1 0 Gamma-glutamyl cyclotransferase, AIG2-like U-box PF04564.15 EGR29589.1 - 2.4e-08 34.0 0.1 4e-08 33.3 0.1 1.4 1 0 0 1 1 1 1 U-box domain CN_hydrolase PF00795.22 EGR29589.1 - 2.9e-07 30.1 0.0 3.7e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DnaJ_C PF01556.18 EGR29590.1 - 2.6e-29 102.2 1.0 1.9e-28 99.4 1.0 2.2 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EGR29590.1 - 4e-10 39.9 19.7 7.9e-10 39.0 19.7 1.5 1 0 0 1 1 1 1 DnaJ central domain PRCH PF03967.13 EGR29590.1 - 0.16 12.2 1.7 16 5.8 0.0 3.0 3 0 0 3 3 3 0 Photosynthetic reaction centre, H-chain N-terminal region zf-RING_10 PF16685.5 EGR29590.1 - 3.3 7.9 9.8 0.12 12.5 0.6 2.4 1 1 1 2 2 2 0 zinc RING finger of MSL2 Anti-TRAP PF15777.5 EGR29590.1 - 4 7.5 17.8 2.6 8.1 3.5 2.6 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein Beta_helix PF13229.6 EGR29591.1 - 3.8e-25 88.6 80.5 1.8e-11 44.2 15.3 4.2 1 1 3 4 4 4 4 Right handed beta helix region NosD PF05048.13 EGR29591.1 - 1.1e-18 67.4 77.4 1.2e-12 47.6 10.8 4.1 2 1 2 4 4 4 3 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 EGR29591.1 - 0.0057 16.0 0.7 0.0057 16.0 0.7 5.3 1 1 4 5 5 5 1 Protein of unknown function (DUF1565) AAA_28 PF13521.6 EGR29592.1 - 1.5e-21 77.3 0.0 4.3e-21 75.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 EGR29592.1 - 0.00093 18.2 0.1 0.0017 17.4 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF1611 PF07755.11 EGR29592.1 - 0.008 15.5 0.3 0.023 13.9 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1611_C) P-loop domain Thymidylate_kin PF02223.17 EGR29592.1 - 0.017 14.8 0.1 0.053 13.2 0.0 1.9 2 1 0 2 2 2 0 Thymidylate kinase AAA_24 PF13479.6 EGR29592.1 - 0.038 13.7 0.1 0.18 11.5 0.1 2.1 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGR29592.1 - 0.086 12.8 0.6 0.2 11.6 0.2 1.8 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 EGR29592.1 - 0.11 12.2 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGR29592.1 - 0.26 11.8 1.3 0.73 10.4 0.8 2.3 1 1 1 2 2 2 0 AAA domain cNMP_binding PF00027.29 EGR29593.1 - 1.6e-15 57.0 0.0 3.7e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Pex24p PF06398.11 EGR29594.1 - 1.7e-14 53.6 17.2 6.9e-14 51.6 17.2 1.8 1 1 0 1 1 1 1 Integral peroxisomal membrane peroxin FTR1 PF03239.14 EGR29594.1 - 0.062 12.5 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Iron permease FTR1 family Phospholip_B PF04916.13 EGR29595.1 - 1.7e-103 347.0 10.0 4.8e-94 315.8 7.1 2.2 1 1 1 2 2 2 2 Phospholipase B GST_N_4 PF17172.4 EGR29595.1 - 0.016 15.9 0.2 0.079 13.7 0.2 2.3 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain SOUL PF04832.12 EGR29595.1 - 0.26 11.4 2.4 0.53 10.4 0.0 2.6 2 0 0 2 2 2 0 SOUL heme-binding protein DUF1281 PF06924.11 EGR29595.1 - 1.1 8.8 8.6 0.38 10.3 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1281) Lectin_N PF03954.14 EGR29595.1 - 3.5 7.4 16.2 0.76 9.5 1.6 2.8 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Copine PF07002.16 EGR29597.1 - 8.6e-19 67.9 0.6 1.4e-18 67.2 0.6 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 EGR29597.1 - 3.8e-11 43.2 0.1 7.9e-11 42.2 0.1 1.4 1 0 0 1 1 1 1 C2 domain LCAT PF02450.15 EGR29598.1 - 2.1e-22 79.8 3.5 3.7e-22 79.0 3.5 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Ser_hydrolase PF06821.13 EGR29598.1 - 0.23 11.3 0.0 0.46 10.3 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase GP41 PF00517.17 EGR29599.1 - 1 9.2 4.0 1.4 8.8 4.0 1.2 1 0 0 1 1 1 0 Retroviral envelope protein P34-Arc PF04045.14 EGR29600.1 - 6.9e-08 32.5 1.0 0.00019 21.3 0.3 2.2 1 1 1 2 2 2 2 Arp2/3 complex, 34 kD subunit p34-Arc ARPC4 PF05856.12 EGR29600.1 - 0.0061 16.2 0.2 0.011 15.3 0.2 1.4 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Cas_Csa5 PF09702.10 EGR29600.1 - 0.061 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csa5) Trimer_CC PF08954.11 EGR29601.1 - 0.03 13.9 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 Trimerisation motif DUF2730 PF10805.8 EGR29602.1 - 5.1 7.3 17.5 9.6 6.4 0.2 5.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2730) E1-E2_ATPase PF00122.20 EGR29603.1 - 3.4e-40 137.5 1.0 3.4e-40 137.5 1.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGR29603.1 - 2.3e-39 135.0 7.5 7e-39 133.4 7.5 1.9 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGR29603.1 - 5.6e-22 77.6 0.3 1.3e-21 76.5 0.3 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGR29603.1 - 1.6e-17 64.5 1.0 2.5e-11 44.3 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGR29603.1 - 3.4e-10 39.5 0.0 1e-09 37.9 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGR29603.1 - 7.1e-05 22.7 6.5 0.0011 18.7 0.3 3.2 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Herpes_UL4 PF03277.13 EGR29603.1 - 0.12 12.0 0.1 0.24 11.0 0.1 1.4 1 0 0 1 1 1 0 Herpesvirus UL4 family HAD PF12710.7 EGR29603.1 - 0.19 12.1 0.0 2.9 8.3 0.0 2.2 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase MBF2 PF15868.5 EGR29604.1 - 0.17 12.5 1.0 9.4 6.9 0.0 3.1 2 0 0 2 2 2 0 Transcription activator MBF2 CobN-Mg_chel PF02514.16 EGR29605.1 - 0.49 8.1 13.3 0.73 7.5 13.3 1.2 1 0 0 1 1 1 0 CobN/Magnesium Chelatase ALMT PF11744.8 EGR29605.1 - 1.4 7.6 14.5 2.3 7.0 14.5 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Mnd1 PF03962.15 EGR29606.1 - 9.5e-19 67.5 0.6 9.5e-19 67.5 0.6 3.2 3 1 0 4 4 4 1 Mnd1 HTH domain LZ3wCH PF18517.1 EGR29606.1 - 3.4e-14 52.7 2.9 3.4e-14 52.7 2.9 3.3 3 1 0 3 3 3 1 Leucine zipper with capping helix domain Leu_zip PF15294.6 EGR29606.1 - 0.0038 16.8 12.7 0.0038 16.8 12.7 1.8 2 0 0 2 2 2 1 Leucine zipper DUF1492 PF07374.11 EGR29606.1 - 0.021 15.0 2.1 0.021 15.0 2.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1492) Adhesin_P1_N PF18652.1 EGR29606.1 - 0.03 14.3 0.7 0.03 14.3 0.7 2.7 2 1 0 3 3 3 0 Adhesin P1 N-terminal domain DUF668 PF05003.12 EGR29606.1 - 0.27 11.7 3.9 1.3 9.5 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF668) AAA_11 PF13086.6 EGR29606.1 - 3.1 7.5 11.4 4 7.2 11.4 1.3 1 0 0 1 1 1 0 AAA domain DUF763 PF05559.11 EGR29606.1 - 4.9 6.3 7.8 22 4.1 7.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF763) XhlA PF10779.9 EGR29606.1 - 8.7 6.6 14.9 9.5 6.5 5.3 2.8 2 1 0 2 2 2 0 Haemolysin XhlA UPF0172 PF03665.13 EGR29607.1 - 0.032 14.3 0.1 0.058 13.4 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) JAB PF01398.21 EGR29607.1 - 0.09 12.8 0.2 4.7 7.2 0.0 2.4 2 0 0 2 2 2 0 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ERGIC_N PF13850.6 EGR29607.1 - 0.091 13.1 0.1 0.091 13.1 0.1 2.7 4 0 0 4 4 4 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Ribosomal_S6e PF01092.19 EGR29608.1 - 8.6e-54 180.8 0.6 8.6e-54 180.8 0.6 1.8 2 0 0 2 2 2 1 Ribosomal protein S6e MORN PF02493.20 EGR29609.1 - 8.7e-43 141.7 83.1 1.9e-06 27.4 4.0 10.6 11 0 0 11 11 11 10 MORN repeat Tudor_2 PF18104.1 EGR29609.1 - 0.012 15.3 0.6 0.012 15.3 0.6 6.2 6 1 1 7 7 7 0 Jumonji domain-containing protein 2A Tudor domain ALMT PF11744.8 EGR29609.1 - 6.2 5.5 9.5 7.3 5.3 9.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter MRP-S34 PF16053.5 EGR29610.1 - 8.1e-05 22.3 0.6 0.00011 21.8 0.6 1.2 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 MORN PF02493.20 EGR29611.1 - 3.8e-51 168.0 63.9 6.7e-07 28.8 0.7 10.1 10 0 0 10 10 10 9 MORN repeat IQ PF00612.27 EGR29611.1 - 2.3e-05 23.8 0.5 4.7e-05 22.8 0.5 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif CRISPR_Cas2 PF09827.9 EGR29611.1 - 0.031 14.4 0.4 0.27 11.4 0.0 2.7 2 1 0 2 2 2 0 CRISPR associated protein Cas2 Tudor_2 PF18104.1 EGR29611.1 - 0.11 12.2 15.2 6.4 6.5 0.7 6.0 6 1 0 6 6 6 0 Jumonji domain-containing protein 2A Tudor domain DUF1323 PF07037.11 EGR29611.1 - 0.51 10.7 5.4 5.9 7.3 0.3 2.9 3 0 0 3 3 3 0 Putative transcription regulator (DUF1323) Ion_trans PF00520.31 EGR29612.1 - 2.9e-07 30.0 1.2 2.9e-07 30.0 1.2 1.7 1 1 0 1 1 1 1 Ion transport protein Glyco_trans_1_4 PF13692.6 EGR29613.1 - 1.8e-11 44.6 0.0 2.2e-11 44.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Kinesin PF00225.23 EGR29614.1 - 1.1e-81 274.3 6.8 1.6e-81 273.9 6.8 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR29614.1 - 3.2e-18 66.1 1.4 4.5e-18 65.6 0.4 1.8 2 0 0 2 2 2 1 Microtubule binding BK_channel_a PF03493.18 EGR29615.1 - 1.6e-33 114.8 1.6 1.8e-31 108.2 0.2 2.8 2 0 0 2 2 2 2 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 EGR29615.1 - 2.9e-13 49.6 1.2 1.1e-12 47.7 1.2 2.1 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGR29615.1 - 1.1e-12 47.7 23.5 7.2e-12 45.1 23.5 2.1 1 1 0 1 1 1 1 Ion transport protein TrkA_N PF02254.18 EGR29615.1 - 6e-06 26.5 0.2 0.036 14.3 0.0 2.6 2 0 0 2 2 2 2 TrkA-N domain adh_short PF00106.25 EGR29616.1 - 5.1e-52 176.2 0.0 6.3e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGR29616.1 - 1.9e-41 142.1 0.0 2.5e-41 141.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGR29616.1 - 1.2e-09 38.4 0.0 2.5e-09 37.3 0.0 1.5 1 1 0 1 1 1 1 KR domain DUF2605 PF10792.9 EGR29616.1 - 0.018 14.9 0.7 0.041 13.8 0.3 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2605) DapH_N PF08503.10 EGR29616.1 - 0.11 12.7 1.5 1.1 9.6 0.1 2.3 2 0 0 2 2 2 0 Tetrahydrodipicolinate succinyltransferase N-terminal Epimerase PF01370.21 EGR29616.1 - 0.11 11.9 0.0 0.17 11.3 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family SNARE_assoc PF09335.11 EGR29618.1 - 2.5e-18 66.7 6.5 4e-18 66.1 4.9 2.1 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF2663 PF10864.8 EGR29618.1 - 0.081 13.3 3.5 0.27 11.7 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2663) DUF4718 PF15842.5 EGR29619.1 - 0.12 12.2 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4718) Ribul_P_3_epim PF00834.19 EGR29620.1 - 4.6e-55 186.1 0.8 5.7e-55 185.8 0.8 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family QRPTase_C PF01729.19 EGR29620.1 - 0.0085 15.9 0.0 0.011 15.6 0.0 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain His_biosynth PF00977.21 EGR29620.1 - 0.023 14.2 0.1 0.3 10.5 0.0 2.0 2 0 0 2 2 2 0 Histidine biosynthesis protein LcrV PF04792.12 EGR29620.1 - 0.039 13.2 0.0 0.058 12.7 0.0 1.2 1 0 0 1 1 1 0 V antigen (LcrV) protein OMPdecase PF00215.24 EGR29620.1 - 0.048 13.3 0.1 0.12 11.9 0.0 1.6 2 0 0 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family PcrB PF01884.17 EGR29620.1 - 0.068 12.6 0.0 0.084 12.3 0.0 1.1 1 0 0 1 1 1 0 PcrB family Mito_carr PF00153.27 EGR29621.1 - 1.4e-18 66.6 1.2 1.2e-11 44.4 0.1 2.3 2 1 0 2 2 2 2 Mitochondrial carrier protein 7TM_GPCR_Srbc PF10316.9 EGR29621.1 - 0.00052 19.6 0.4 0.00052 19.6 0.4 1.6 2 0 0 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Srbc DUF4118 PF13493.6 EGR29621.1 - 0.11 12.3 0.2 17 5.3 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4118) cNMP_binding PF00027.29 EGR29622.1 - 0.0056 16.7 0.0 0.013 15.5 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF4504 PF14953.6 EGR29622.1 - 0.022 14.2 0.4 0.022 14.2 0.4 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4504) Na_H_Exchanger PF00999.21 EGR29623.1 - 1.2e-51 175.8 36.4 1.6e-51 175.3 36.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Sec23_trunk PF04811.15 EGR29624.1 - 5.8e-40 137.4 0.4 1e-39 136.6 0.4 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain UQ_con PF00179.26 EGR29624.1 - 3.9e-39 133.5 0.2 1.4e-38 131.7 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme zf-Sec23_Sec24 PF04810.15 EGR29624.1 - 9.4e-15 54.4 3.6 2.6e-14 53.0 3.6 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger zf-CCCH PF00642.24 EGR29624.1 - 2.6e-06 27.2 1.2 6.7e-06 25.9 1.2 1.8 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Gelsolin PF00626.22 EGR29624.1 - 1.2e-05 25.1 0.0 3.4e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat zf_CCCH_4 PF18345.1 EGR29624.1 - 1.5e-05 24.9 2.3 5e-05 23.2 2.3 2.0 1 0 0 1 1 1 1 Zinc finger domain Prok-E2_B PF14461.6 EGR29624.1 - 0.00014 21.6 0.0 0.00043 20.0 0.0 1.8 1 0 0 1 1 1 1 Prokaryotic E2 family B zf-CCCH_4 PF18044.1 EGR29624.1 - 0.0031 17.3 1.8 0.01 15.6 1.8 1.9 1 0 0 1 1 1 1 CCCH-type zinc finger UEV PF05743.13 EGR29624.1 - 0.086 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 UEV domain Torus PF16131.5 EGR29624.1 - 0.23 12.2 2.7 0.56 10.9 2.7 1.7 1 0 0 1 1 1 0 Torus domain STAT_int PF02865.17 EGR29624.1 - 1.2 9.7 9.3 0.44 11.0 0.5 3.1 3 0 0 3 3 3 0 STAT protein, protein interaction domain Pkinase PF00069.25 EGR29625.1 - 2.9e-65 220.3 2.5 1.5e-64 217.9 0.1 3.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29625.1 - 2.6e-32 112.1 0.0 9.1e-32 110.4 0.0 1.9 1 0 0 1 1 1 1 Protein tyrosine kinase DUF962 PF06127.11 EGR29625.1 - 1.4e-10 41.1 5.5 2.9e-10 40.1 0.1 3.2 2 0 0 2 2 2 1 Protein of unknown function (DUF962) PAS_9 PF13426.7 EGR29625.1 - 7.2e-07 29.4 3.7 7.2e-07 29.4 0.1 3.0 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 EGR29625.1 - 0.0003 20.7 0.0 0.0022 18.0 0.0 2.4 2 0 0 2 2 2 1 PAS fold DnaGprimase_HBD PF16730.5 EGR29626.1 - 0.018 15.1 4.7 0.025 14.6 1.7 2.0 1 1 1 2 2 2 0 DnaG-primase C-terminal, helicase-binding domain RdDM_RDM1 PF09187.10 EGR29626.1 - 0.14 12.2 1.4 0.17 12.0 1.4 1.2 1 0 0 1 1 1 0 RNA-directed DNA methylation 1 MRP-63 PF14978.6 EGR29626.1 - 0.22 12.2 5.0 0.65 10.7 4.3 1.9 1 1 1 2 2 2 0 Mitochondrial ribosome protein 63 Casein_kappa PF00997.18 EGR29626.1 - 0.55 10.3 15.9 0.2 11.7 5.3 2.5 1 1 2 3 3 3 0 Kappa casein Inositol_P PF00459.25 EGR29628.1 - 3.2e-33 115.4 0.0 3.8e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family Ribosomal_L22 PF00237.19 EGR29630.1 - 7.2e-31 106.5 0.7 4.3e-30 104.0 0.0 1.9 1 1 1 2 2 2 1 Ribosomal protein L22p/L17e RNA_Me_trans PF04252.13 EGR29631.1 - 8.6e-34 116.9 0.0 1e-33 116.6 0.0 1.0 1 0 0 1 1 1 1 Predicted SAM-dependent RNA methyltransferase MORN PF02493.20 EGR29632.1 - 2.3e-45 149.8 60.7 2.4e-07 30.3 0.1 10.5 10 1 0 10 10 10 8 MORN repeat Cnd1 PF12717.7 EGR29633.1 - 1.1e-10 41.7 7.1 8.2e-05 22.7 0.2 2.5 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGR29633.1 - 1.5e-10 40.4 5.2 0.00036 20.5 0.2 4.6 5 1 2 7 7 7 2 HEAT repeat HEAT_EZ PF13513.6 EGR29633.1 - 2.5e-05 24.6 0.1 0.039 14.5 0.0 3.3 3 0 0 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.6 EGR29633.1 - 0.0014 19.0 0.2 17 5.9 0.0 3.6 4 0 0 4 4 4 1 HEAT repeats UNC45-central PF11701.8 EGR29633.1 - 0.002 18.1 5.3 0.043 13.8 0.2 3.2 2 1 0 2 2 2 1 Myosin-binding striated muscle assembly central UCR_14kD PF02271.16 EGR29633.1 - 0.0042 17.0 0.3 0.014 15.3 0.0 2.0 2 0 0 2 2 2 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Vac14_Fab1_bd PF12755.7 EGR29633.1 - 0.011 16.3 3.7 1.6 9.4 0.3 3.0 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Cohesin_HEAT PF12765.7 EGR29633.1 - 0.083 13.2 0.0 29 5.1 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Cullin PF00888.22 EGR29634.1 - 3.7e-74 250.4 33.8 5.6e-74 249.9 33.8 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGR29634.1 - 8e-15 54.6 3.0 1.4e-14 53.9 0.7 2.8 2 0 0 2 2 2 1 Cullin protein neddylation domain GAT PF03127.14 EGR29634.1 - 0.028 14.7 1.0 0.2 12.0 0.1 2.9 2 0 0 2 2 2 0 GAT domain DUF4524 PF15025.6 EGR29634.1 - 0.084 12.6 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) NusB PF01029.18 EGR29634.1 - 1.9 8.7 10.6 12 6.2 1.1 4.4 4 1 1 5 5 5 0 NusB family AHSA1 PF08327.11 EGR29635.1 - 3.5e-14 53.1 0.0 4.2e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein zf-CDGSH PF09360.10 EGR29636.1 - 1.1e-09 38.3 11.5 2.9e-05 24.2 1.1 3.4 3 1 0 3 3 3 2 Iron-binding zinc finger CDGSH type Lip_prot_lig_C PF10437.9 EGR29638.1 - 0.049 13.6 0.1 0.062 13.3 0.1 1.3 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus Pkinase PF00069.25 EGR29639.1 - 7.1e-69 232.1 0.3 7.9e-69 231.9 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29639.1 - 2.7e-44 151.4 0.0 3e-44 151.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR29639.1 - 1.1e-07 31.0 0.0 1.3e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGR29639.1 - 5.8e-05 22.6 0.6 0.00037 19.9 0.1 2.3 2 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EGR29639.1 - 0.00023 20.9 0.0 0.00028 20.6 0.0 1.2 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EGR29639.1 - 0.00045 19.9 0.1 0.00068 19.3 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGR29639.1 - 0.0059 16.0 0.1 0.0086 15.4 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EGR29639.1 - 0.039 13.0 0.3 0.063 12.3 0.3 1.5 1 1 0 1 1 1 0 Seadornavirus VP7 C2 PF00168.30 EGR29640.1 - 4.8e-51 171.3 12.8 1.8e-16 60.3 0.0 7.8 8 1 0 8 8 8 5 C2 domain FerI PF08151.12 EGR29640.1 - 0.00056 19.9 0.1 0.0025 17.8 0.1 2.3 1 0 0 1 1 1 1 FerI (NUC094) domain Cullin PF00888.22 EGR29642.1 - 1.6e-21 76.6 6.7 1.6e-21 76.6 6.7 1.8 1 1 1 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 EGR29642.1 - 6.4e-18 64.5 3.2 2.3e-17 62.8 3.2 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain Pkinase PF00069.25 EGR29643.1 - 4.8e-17 62.2 3.3 7.3e-17 61.6 3.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29643.1 - 1.1e-11 44.5 1.3 1.7e-11 43.9 1.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EGR29644.1 - 1.9e-21 76.3 33.8 2.1e-06 28.1 0.3 7.8 6 2 2 8 8 8 6 EF-hand domain pair EF-hand_6 PF13405.6 EGR29644.1 - 4.7e-20 69.7 32.6 0.04 13.9 0.7 10.8 10 1 0 11 11 11 7 EF-hand domain EF-hand_1 PF00036.32 EGR29644.1 - 2.6e-18 64.1 34.0 0.0051 16.3 1.1 9.5 9 0 0 9 9 9 6 EF hand EF-hand_8 PF13833.6 EGR29644.1 - 3e-08 33.4 33.7 0.0037 17.1 0.3 9.2 8 2 2 10 10 10 4 EF-hand domain pair EF-hand_9 PF14658.6 EGR29644.1 - 6.2e-05 23.2 2.3 0.54 10.6 0.0 5.2 5 0 0 5 5 5 1 EF-hand domain EF-hand_5 PF13202.6 EGR29644.1 - 0.01 15.3 18.7 0.16 11.5 0.1 6.6 6 0 0 6 6 6 1 EF hand Phg_2220_C PF09524.10 EGR29644.1 - 0.38 10.9 8.9 0.028 14.5 1.6 3.2 3 0 0 3 3 3 0 Conserved phage C-terminus (Phg_2220_C) Pkinase PF00069.25 EGR29645.1 - 3.4e-59 200.4 0.1 4.1e-59 200.1 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29645.1 - 6.8e-36 123.9 0.0 8.4e-36 123.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR29645.1 - 0.0008 18.5 0.1 0.0012 17.9 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGR29645.1 - 0.00097 18.5 0.1 0.0013 18.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGR29645.1 - 0.0028 17.0 0.0 0.0053 16.1 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EGR29645.1 - 0.031 13.4 0.0 0.052 12.6 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Pkinase_fungal PF17667.1 EGR29645.1 - 0.032 13.0 0.0 0.052 12.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase KH_1 PF00013.29 EGR29646.1 - 0.036 13.9 0.7 0.12 12.2 0.7 2.0 1 0 0 1 1 1 0 KH domain HEAT PF02985.22 EGR29647.1 - 0.15 12.4 0.0 22 5.6 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat ADK PF00406.22 EGR29649.1 - 1.2e-48 165.0 1.6 2.2e-27 96.0 0.0 2.2 2 0 0 2 2 2 2 Adenylate kinase AAA_17 PF13207.6 EGR29649.1 - 3.5e-25 89.0 0.2 3.2e-11 43.8 0.0 2.9 2 1 1 3 3 3 2 AAA domain Hydin_ADK PF17213.3 EGR29649.1 - 7.4e-11 42.7 4.8 0.0026 18.0 0.0 4.0 3 1 0 4 4 4 3 Hydin Adenylate kinase-like domain AAA_18 PF13238.6 EGR29649.1 - 1.8e-10 41.5 0.3 1.4e-06 28.9 0.0 3.1 2 1 1 3 3 3 2 AAA domain AAA_33 PF13671.6 EGR29649.1 - 9.3e-06 25.9 0.0 0.0062 16.7 0.1 3.0 2 2 0 2 2 2 1 AAA domain AAA PF00004.29 EGR29649.1 - 2.6e-05 24.6 0.1 0.038 14.4 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EGR29649.1 - 5.9e-05 23.4 0.0 0.04 14.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.12 EGR29649.1 - 0.00015 21.6 0.0 0.2 11.4 0.0 2.5 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain Cytidylate_kin2 PF13189.6 EGR29649.1 - 0.00016 21.9 0.0 0.11 12.6 0.0 2.9 3 0 0 3 3 3 1 Cytidylate kinase-like family AAA_5 PF07728.14 EGR29649.1 - 0.00023 21.2 0.0 0.24 11.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) Cytidylate_kin PF02224.18 EGR29649.1 - 0.00067 19.4 0.2 0.1 12.3 0.0 2.6 2 1 0 2 2 2 1 Cytidylate kinase DUF5586 PF17824.1 EGR29649.1 - 0.0032 16.6 0.2 0.0032 16.6 0.2 1.6 2 0 0 2 2 2 1 Family of unknown function (DUF5586) Ploopntkinase3 PF18751.1 EGR29649.1 - 0.004 17.1 0.0 2.7 7.9 0.0 2.3 2 0 0 2 2 2 2 P-loop Nucleotide Kinase3 ANF_receptor PF01094.28 EGR29649.1 - 0.012 14.7 0.0 4.5 6.3 0.0 2.2 2 0 0 2 2 2 0 Receptor family ligand binding region AAA_22 PF13401.6 EGR29649.1 - 0.02 15.2 0.1 0.088 13.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EGR29649.1 - 0.051 13.3 0.0 0.53 10.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein SKI PF01202.22 EGR29649.1 - 0.058 13.5 0.1 2.1 8.4 0.0 2.8 3 0 0 3 3 3 0 Shikimate kinase AAA_16 PF13191.6 EGR29649.1 - 0.072 13.5 0.0 1.6 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.12 EGR29649.1 - 0.086 12.1 0.1 1.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 EGR29649.1 - 0.14 11.5 0.0 3.7 6.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI RRM_1 PF00076.22 EGR29650.1 - 2.8e-17 62.3 1.4 3.6e-11 42.7 0.0 4.4 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGR29650.1 - 6.2e-06 26.0 0.5 0.011 15.6 0.0 3.9 4 0 0 4 4 4 2 Occluded RNA-recognition motif Aminotran_1_2 PF00155.21 EGR29652.1 - 6.7e-55 186.7 0.0 3.9e-54 184.2 0.0 1.8 1 1 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGR29652.1 - 4.7e-06 25.4 0.1 0.00073 18.2 0.1 2.2 2 0 0 2 2 2 2 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGR29652.1 - 0.0013 17.8 0.0 0.0033 16.4 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Met_gamma_lyase PF06838.11 EGR29652.1 - 0.0055 15.3 0.0 0.0086 14.6 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase SRP54 PF00448.22 EGR29652.1 - 0.044 13.4 0.1 0.07 12.8 0.1 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MORN PF02493.20 EGR29653.1 - 1.3e-23 81.4 23.7 5e-07 29.3 0.3 6.1 6 0 0 6 6 6 5 MORN repeat ADH_N_2 PF16884.5 EGR29654.1 - 9.1e-26 89.9 0.0 1.9e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EGR29654.1 - 3.5e-08 33.5 0.4 5.6e-08 32.8 0.4 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Synaptobrevin PF00957.21 EGR29655.1 - 6.1e-20 70.8 1.8 7.7e-20 70.5 1.8 1.1 1 0 0 1 1 1 1 Synaptobrevin Orf78 PF06024.12 EGR29655.1 - 0.0034 17.7 0.4 0.0043 17.3 0.4 1.1 1 0 0 1 1 1 1 Orf78 (ac78) DUF1664 PF07889.12 EGR29655.1 - 0.03 14.4 1.9 0.046 13.8 1.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Ferlin_C PF16165.5 EGR29655.1 - 0.05 13.6 1.2 0.069 13.1 1.2 1.4 1 1 0 1 1 1 0 Ferlin C-terminus Sec20 PF03908.13 EGR29655.1 - 0.077 12.9 0.3 0.12 12.3 0.3 1.4 1 0 0 1 1 1 0 Sec20 HEPN_RiboL-PSP PF18735.1 EGR29655.1 - 0.083 12.8 6.0 0.1 12.5 6.0 1.1 1 0 0 1 1 1 0 RiboL-PSP-HEPN DUF848 PF05852.11 EGR29655.1 - 0.17 12.0 2.1 0.46 10.6 2.1 1.7 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF1090 PF06476.12 EGR29655.1 - 0.61 10.2 7.7 0.27 11.4 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) XhlA PF10779.9 EGR29655.1 - 2.8 8.2 8.0 1.5 9.1 4.5 2.1 1 1 1 2 2 2 0 Haemolysin XhlA Acatn PF13000.7 EGR29656.1 - 1.6e-29 102.9 12.4 1.4e-28 99.7 12.4 2.0 1 1 0 1 1 1 1 Acetyl-coenzyme A transporter 1 MMR_HSR1 PF01926.23 EGR29656.1 - 4.6e-09 36.4 0.0 7.5e-09 35.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGR29656.1 - 4.3e-05 23.6 0.0 7e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Dynamin family MFS_1 PF07690.16 EGR29656.1 - 0.00038 19.5 1.2 0.00046 19.2 1.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily FeoB_N PF02421.18 EGR29656.1 - 0.00094 18.7 0.0 0.0017 17.9 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Roc PF08477.13 EGR29656.1 - 0.022 15.0 0.0 0.041 14.1 0.0 1.4 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EGR29656.1 - 0.034 13.5 0.0 0.053 12.9 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family Arf PF00025.21 EGR29656.1 - 0.048 13.1 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 ADP-ribosylation factor family TniB PF05621.11 EGR29656.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein DUF3667 PF12412.8 EGR29656.1 - 0.089 12.3 0.2 0.24 11.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3667) WD40 PF00400.32 EGR29658.1 - 7.5e-47 156.3 14.1 4.5e-09 36.8 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR29658.1 - 5.1e-16 58.8 1.8 0.0067 16.7 0.0 5.8 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 EGR29658.1 - 3.8e-08 31.9 1.8 7.4e-08 30.9 1.8 1.5 1 1 0 1 1 1 1 IKI3 family Pkinase PF00069.25 EGR29659.1 - 4e-83 278.8 0.1 6.8e-83 278.1 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29659.1 - 2.9e-40 138.2 0.0 4.7e-40 137.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 EGR29659.1 - 1.3e-18 65.1 6.4 7.9e-06 25.1 0.2 3.8 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EGR29659.1 - 1.3e-17 62.2 4.4 1.9e-05 24.2 0.2 4.0 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 EGR29659.1 - 3.7e-16 59.3 3.4 3.1e-10 40.3 0.4 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EGR29659.1 - 9.9e-16 56.4 4.7 0.00066 19.1 0.1 3.6 3 0 0 3 3 3 3 EF hand Kdo PF06293.14 EGR29659.1 - 8.1e-08 31.9 0.0 1.7e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.9 EGR29659.1 - 1.3e-06 28.7 1.7 0.00012 22.4 0.1 2.6 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.6 EGR29659.1 - 5.3e-06 26.0 0.0 1.2e-05 24.8 0.0 1.6 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGR29659.1 - 1.6e-05 25.0 0.0 4.6e-05 23.5 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family EF-hand_8 PF13833.6 EGR29659.1 - 0.00015 21.6 7.5 0.04 13.8 1.4 3.6 1 1 2 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 EGR29659.1 - 0.00041 20.3 1.1 0.0016 18.4 0.7 2.3 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand NESP55 PF06390.12 EGR29660.1 - 0.0013 18.4 0.1 0.0017 18.0 0.1 1.1 1 0 0 1 1 1 1 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.11 EGR29660.1 - 0.0033 17.4 1.0 0.0052 16.8 1.0 1.2 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) cNMP_binding PF00027.29 EGR29661.1 - 1.6e-43 146.7 0.0 3.3e-21 75.2 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Dpy-30 PF05186.13 EGR29661.1 - 9.3e-06 25.2 0.6 1.9e-05 24.3 0.6 1.5 1 0 0 1 1 1 1 Dpy-30 motif DUF5586 PF17824.1 EGR29661.1 - 5e-05 22.6 0.3 0.00013 21.2 0.1 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5586) Cytomega_UL84 PF06284.11 EGR29661.1 - 0.12 10.8 1.0 0.17 10.3 1.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein FAM176 PF14851.6 EGR29661.1 - 1.4 8.6 3.6 2.3 7.9 3.6 1.3 1 0 0 1 1 1 0 FAM176 family Ribosomal_60s PF00428.19 EGR29661.1 - 1.6 9.4 11.4 1.2 9.8 9.3 1.9 1 1 0 1 1 1 0 60s Acidic ribosomal protein Presenilin PF01080.17 EGR29661.1 - 2.1 7.0 3.3 2.7 6.7 3.3 1.1 1 0 0 1 1 1 0 Presenilin LRR_4 PF12799.7 EGR29662.1 - 1.7e-11 44.1 25.8 0.00036 20.9 0.0 8.1 5 3 2 8 8 8 5 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGR29662.1 - 6.6e-06 25.9 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGR29662.1 - 7.4e-05 22.5 0.0 0.00022 21.0 0.0 1.8 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 EGR29662.1 - 4.2 7.2 13.4 11 5.9 0.1 5.6 3 2 2 5 5 5 0 Leucine rich repeat Cyclin_N PF00134.23 EGR29663.1 - 5.4e-31 107.0 0.3 1e-30 106.1 0.3 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF5595 PF18077.1 EGR29663.1 - 0.042 13.9 0.1 0.042 13.9 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5595) Glyco_hydro_31 PF01055.26 EGR29664.1 - 3.6e-114 382.4 3.9 4.6e-114 382.0 3.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 RabGAP-TBC PF00566.18 EGR29665.1 - 1.2e-40 139.5 10.4 1.2e-40 139.5 10.4 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ArAE_2 PF10334.9 EGR29665.1 - 0.017 14.9 0.3 0.032 14.1 0.3 1.4 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 Swm2 PF17083.5 EGR29666.1 - 0.014 15.4 1.8 0.031 14.3 1.8 1.5 1 0 0 1 1 1 0 Nucleolar protein Swm2 UCH PF00443.29 EGR29667.1 - 5.2e-59 199.8 11.0 6.1e-59 199.6 11.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR29667.1 - 5e-22 78.9 11.8 6.4e-22 78.6 11.8 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase MOR2-PAG1_C PF14225.6 EGR29667.1 - 0.0034 17.3 0.1 0.0066 16.3 0.1 1.4 1 0 0 1 1 1 1 Cell morphogenesis C-terminal GDNF PF02351.16 EGR29667.1 - 0.011 16.7 0.8 0.011 16.7 0.8 2.3 3 0 0 3 3 3 0 GDNF/GAS1 domain DUF334 PF03904.13 EGR29667.1 - 0.019 14.5 2.0 0.033 13.7 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF334) Glyco_hydro_64 PF16483.5 EGR29667.1 - 0.027 13.8 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 Beta-1,3-glucanase zf-C3HC PF07967.13 EGR29667.1 - 0.034 14.2 1.6 0.17 11.9 1.6 2.3 1 1 0 1 1 1 0 C3HC zinc finger-like MyTH4 PF00784.17 EGR29667.1 - 0.23 12.0 2.8 4.3 7.9 0.2 2.7 2 1 0 2 2 2 0 MyTH4 domain VHL_C PF17211.3 EGR29667.1 - 0.48 10.5 2.1 0.53 10.3 0.4 2.0 2 0 0 2 2 2 0 VHL box domain NAD_binding_1 PF00175.21 EGR29669.1 - 1e-12 48.6 0.2 8.9e-08 32.8 0.0 2.6 3 0 0 3 3 3 2 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 EGR29669.1 - 4.6e-09 36.2 0.1 6.8e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain NAD_binding_6 PF08030.12 EGR29669.1 - 0.0049 17.0 0.2 0.026 14.6 0.2 2.2 1 1 0 1 1 1 1 Ferric reductase NAD binding domain MRP-L46 PF11788.8 EGR29669.1 - 0.34 11.7 0.1 0.34 11.7 0.1 1.9 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 L_protein_N PF15518.6 EGR29670.1 - 0.05 13.4 0.2 0.19 11.6 0.1 1.9 2 0 0 2 2 2 0 L protein N-terminus adh_short PF00106.25 EGR29671.1 - 1.1e-09 38.0 0.0 3.2e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGR29671.1 - 2.5e-05 24.0 0.0 0.00058 19.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGR29671.1 - 0.016 15.2 0.0 0.029 14.3 0.0 1.5 1 1 0 1 1 1 0 KR domain Baculo_LEF-11 PF06385.12 EGR29671.1 - 0.043 14.3 0.5 0.15 12.6 0.1 2.1 2 0 0 2 2 2 0 Baculovirus LEF-11 protein Peptidase_M8 PF01457.16 EGR29674.1 - 1.5e-40 139.4 0.0 2.9e-40 138.4 0.0 1.4 1 1 1 2 2 2 1 Leishmanolysin Zincin_1 PF06262.11 EGR29674.1 - 0.19 11.9 0.0 0.38 10.9 0.0 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase Pkinase PF00069.25 EGR29675.1 - 2.4e-06 27.1 1.5 3.3e-06 26.7 1.5 1.2 1 0 0 1 1 1 1 Protein kinase domain HMGL-like PF00682.19 EGR29676.1 - 3.2e-15 56.4 0.0 3.8e-15 56.2 0.0 1.1 1 0 0 1 1 1 1 HMGL-like DIOX_N PF14226.6 EGR29677.1 - 0.0013 19.5 0.8 0.0042 17.8 0.3 2.3 2 1 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGR29677.1 - 0.0087 16.5 0.0 0.014 15.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pur_ac_phosph_N PF16656.5 EGR29681.1 - 0.068 13.8 3.0 1.8 9.2 1.0 3.3 2 1 0 2 2 2 0 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 EGR29681.1 - 0.093 13.1 0.2 19 5.7 0.0 3.0 3 0 0 3 3 3 0 Fibronectin type III domain CEP19 PF14933.6 EGR29686.1 - 0.03 14.6 9.8 0.07 13.4 9.8 1.6 1 0 0 1 1 1 0 CEP19-like protein Herp-Cyclin PF09241.10 EGR29686.1 - 0.13 12.9 0.1 0.32 11.7 0.1 1.6 1 0 0 1 1 1 0 Herpesviridae viral cyclin MnmE_helical PF12631.7 EGR29686.1 - 1.1 9.4 8.0 1.7 8.8 8.0 1.3 1 0 0 1 1 1 0 MnmE helical domain PCRF PF03462.18 EGR29686.1 - 9.5 6.0 12.9 4.9 7.0 10.7 1.7 2 0 0 2 2 2 0 PCRF domain Rubis-subs-bind PF09273.11 EGR29687.1 - 1.2e-14 55.1 0.7 2e-13 51.2 0.0 2.3 2 1 0 2 2 2 1 Rubisco LSMT substrate-binding Enkurin PF13864.6 EGR29687.1 - 2e-14 53.8 11.4 2e-14 53.8 11.4 1.8 2 0 0 2 2 2 1 Calmodulin-binding XhlA PF10779.9 EGR29687.1 - 0.22 11.7 2.3 0.68 10.2 2.3 1.9 1 0 0 1 1 1 0 Haemolysin XhlA WD40 PF00400.32 EGR29688.1 - 8e-14 51.8 4.4 0.63 11.0 0.0 8.4 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR29688.1 - 7.1e-06 26.2 0.3 7.9 6.9 0.0 6.1 4 1 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain DUF667 PF05018.13 EGR29689.1 - 2.6e-19 69.7 6.4 2.6e-19 69.7 6.4 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF667) WD40 PF00400.32 EGR29689.1 - 1.3e-06 29.0 1.0 4.3e-05 24.2 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat PDDEXK_6 PF04720.12 EGR29689.1 - 0.0013 18.8 4.0 0.0013 18.8 4.0 1.7 2 0 0 2 2 2 1 PDDEXK-like family of unknown function DUF4199 PF13858.6 EGR29689.1 - 1.3 9.4 4.7 0.63 10.4 1.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) zf-C2HC_2 PF13913.6 EGR29690.1 - 9.3e-43 143.4 41.1 1e-09 38.0 2.0 6.5 7 0 0 7 7 6 6 zinc-finger of a C2HC-type zf-C2H2 PF00096.26 EGR29690.1 - 1.7e-06 28.2 18.5 0.5 10.9 0.7 6.0 6 0 0 6 6 5 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGR29690.1 - 4.1e-06 27.2 26.7 0.28 12.1 2.2 6.0 6 0 0 6 6 5 3 C2H2-type zinc finger Rad50_zn_hook PF04423.14 EGR29690.1 - 0.0003 20.6 2.3 0.97 9.3 0.0 4.5 4 0 0 4 4 4 1 Rad50 zinc hook motif PyrI_C PF02748.15 EGR29690.1 - 0.0011 18.8 1.9 15 5.6 0.0 4.4 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain DUF2318 PF10080.9 EGR29690.1 - 0.0014 18.7 15.6 1.1 9.4 0.3 5.4 4 1 1 5 5 5 1 Predicted membrane protein (DUF2318) zf-C2H2_jaz PF12171.8 EGR29690.1 - 0.0068 16.7 10.0 2.8 8.4 0.2 5.2 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding DUF2256 PF10013.9 EGR29690.1 - 0.0073 16.4 13.2 2.8 8.1 0.1 5.9 5 0 0 5 5 5 1 Uncharacterized protein conserved in bacteria (DUF2256) zf-C2H2_11 PF16622.5 EGR29690.1 - 0.023 14.5 8.1 1.4 8.8 0.0 3.8 4 0 0 4 4 4 0 zinc-finger C2H2-type FYVE PF01363.21 EGR29690.1 - 0.15 12.2 16.1 1.7 8.8 0.7 5.2 5 0 0 5 5 5 0 FYVE zinc finger zf-CHCC PF10276.9 EGR29690.1 - 0.38 10.8 11.8 7.8 6.6 0.1 4.8 5 0 0 5 5 5 0 Zinc-finger domain HNH_5 PF14279.6 EGR29690.1 - 1.2 9.0 13.4 29 4.6 0.1 5.4 5 1 1 6 6 6 0 HNH endonuclease zf_UBZ PF18439.1 EGR29690.1 - 1.9 8.1 10.0 24 4.6 0.1 5.0 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-Di19 PF05605.12 EGR29690.1 - 2.1 8.7 20.2 1.5 9.2 0.8 5.0 5 0 0 5 5 5 0 Drought induced 19 protein (Di19), zinc-binding Sigma_reg_C PF13791.6 EGR29690.1 - 2.2 8.5 10.1 0.14 12.4 4.0 2.1 2 0 0 2 2 2 0 Sigma factor regulator C-terminal zf-H2C2_2 PF13465.6 EGR29690.1 - 3.6 8.2 15.0 16 6.1 0.2 5.5 6 0 0 6 6 5 0 Zinc-finger double domain Zf_RING PF16744.5 EGR29690.1 - 5.8 7.1 15.5 1.7 8.8 0.1 5.2 6 0 0 6 6 6 0 KIAA1045 RING finger zf-RING_7 PF02591.15 EGR29690.1 - 10 6.4 7.3 2.1 8.6 0.1 3.4 4 0 0 4 4 4 0 C4-type zinc ribbon domain DHHC PF01529.20 EGR29691.1 - 4.1e-26 91.7 11.2 4.1e-26 91.7 11.2 2.3 2 0 0 2 2 2 1 DHHC palmitoyltransferase DUF4378 PF14309.6 EGR29693.1 - 1.3e-07 32.1 1.0 1.7e-07 31.8 1.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4378) Gluconate_2-dh3 PF13618.6 EGR29693.1 - 0.066 13.5 0.1 1.6 8.9 0.1 2.4 1 1 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Csm1_B PF18211.1 EGR29693.1 - 0.32 10.8 2.6 16 5.4 0.0 3.1 2 1 1 3 3 3 0 Csm1 subunit domain B DUF917 PF06032.12 EGR29694.1 - 1.9e-68 230.9 0.0 2.8e-51 174.4 0.0 2.3 1 1 1 2 2 2 2 Protein of unknown function (DUF917) Hydantoinase_A PF01968.18 EGR29694.1 - 7e-15 55.0 0.0 2.6e-14 53.2 0.0 1.8 1 1 0 1 1 1 1 Hydantoinase/oxoprolinase MutL PF13941.6 EGR29694.1 - 0.012 14.2 0.0 0.022 13.4 0.0 1.3 1 0 0 1 1 1 0 MutL protein FtsA PF14450.6 EGR29694.1 - 0.036 14.5 0.3 0.18 12.3 0.1 2.2 2 0 0 2 2 2 0 Cell division protein FtsA MreB_Mbl PF06723.13 EGR29694.1 - 0.13 11.1 1.0 1.8 7.3 0.0 2.7 3 0 0 3 3 3 0 MreB/Mbl protein PP2C PF00481.21 EGR29696.1 - 6e-35 121.1 0.1 1.4e-32 113.4 0.0 2.2 1 1 1 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 EGR29696.1 - 0.0027 17.7 0.0 0.078 12.9 0.0 2.2 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) NifU PF01106.17 EGR29696.1 - 0.068 13.3 0.1 0.23 11.6 0.1 1.9 1 1 0 1 1 1 0 NifU-like domain HATPase_c PF02518.26 EGR29697.1 - 3.8e-22 78.9 0.9 7.9e-22 77.9 0.9 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGR29697.1 - 3.8e-20 72.1 2.1 8.1e-20 71.1 0.8 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EGR29697.1 - 3.9e-11 42.8 0.1 1.2e-10 41.3 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EGR29697.1 - 0.00012 21.9 0.3 0.00044 20.1 0.3 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase His_Phos_2 PF00328.22 EGR29698.1 - 1.8e-24 86.8 0.9 5.2e-21 75.4 0.7 2.2 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) RIFIN PF02009.16 EGR29698.1 - 0.0056 16.6 0.9 0.0056 16.6 0.9 1.6 2 0 0 2 2 2 1 Rifin TMEM154 PF15102.6 EGR29698.1 - 0.046 13.6 0.4 0.11 12.4 0.4 1.6 1 0 0 1 1 1 0 TMEM154 protein family CPSF73-100_C PF11718.8 EGR29698.1 - 0.08 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Ion_trans_2 PF07885.16 EGR29699.1 - 1e-09 38.2 1.1 1.3e-09 37.9 1.1 1.1 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGR29699.1 - 1.5e-05 24.4 0.1 1.7e-05 24.2 0.1 1.1 1 0 0 1 1 1 1 Ion transport protein ICE2 PF08426.10 EGR29699.1 - 0.051 12.7 0.1 0.052 12.6 0.1 1.1 1 0 0 1 1 1 0 ICE2 Kinesin PF00225.23 EGR29700.1 - 2e-96 322.8 2.9 2.3e-96 322.6 2.9 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR29700.1 - 1e-21 77.4 1.4 2e-21 76.5 1.4 1.4 1 0 0 1 1 1 1 Microtubule binding Peptidase_M8 PF01457.16 EGR29701.1 - 2.6e-54 184.8 6.6 1.2e-49 169.4 0.0 2.3 1 1 1 2 2 2 2 Leishmanolysin EGF_2 PF07974.13 EGR29701.1 - 3.3e-05 24.2 12.6 3.3e-05 24.2 12.6 2.8 4 0 0 4 4 4 1 EGF-like domain EGF_Tenascin PF18720.1 EGR29701.1 - 0.0016 18.5 6.2 0.0041 17.1 6.2 1.8 1 0 0 1 1 1 1 Tenascin EGF domain hEGF PF12661.7 EGR29701.1 - 0.13 12.9 6.5 1 10.1 6.5 2.7 1 0 0 1 1 1 0 Human growth factor-like EGF NCD3G PF07562.14 EGR29702.1 - 0.00012 22.0 17.2 0.0027 17.6 0.9 3.7 2 1 0 3 3 3 2 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.13 EGR29702.1 - 0.0015 18.2 3.0 0.0015 18.2 3.0 4.2 3 2 1 4 4 4 2 Putative ephrin-receptor like Laminin_EGF PF00053.24 EGR29702.1 - 0.66 10.2 17.8 1.5 9.0 2.4 4.0 3 2 0 3 3 3 0 Laminin EGF domain Furin-like_2 PF15913.5 EGR29702.1 - 2 8.6 11.5 0.72 10.0 4.5 2.6 1 1 1 2 2 2 0 Furin-like repeat, cysteine-rich Response_reg PF00072.24 EGR29703.1 - 4.2e-17 62.3 0.1 1.6e-16 60.5 0.1 2.1 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EGR29703.1 - 7.3e-13 49.0 0.7 2.1e-12 47.6 0.7 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGR29703.1 - 5.9e-05 22.9 2.9 6.7e-05 22.7 0.2 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGR29703.1 - 0.00076 19.5 0.1 0.0024 17.9 0.1 1.9 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Scramblase PF03803.15 EGR29704.1 - 9.1e-33 113.4 0.3 1.6e-32 112.6 0.3 1.4 1 1 0 1 1 1 1 Scramblase Pkinase PF00069.25 EGR29705.1 - 6.7e-64 215.8 1.4 7.7e-64 215.6 1.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29705.1 - 5.2e-38 130.8 0.1 6.2e-38 130.6 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR29705.1 - 0.0038 16.1 0.1 0.0052 15.6 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR29705.1 - 0.088 12.2 0.2 0.17 11.2 0.0 1.5 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family SIR2 PF02146.17 EGR29706.1 - 1.7e-56 190.9 0.0 3.3e-56 190.0 0.0 1.5 1 0 0 1 1 1 1 Sir2 family zf-UBP PF02148.19 EGR29706.1 - 1.1e-06 28.8 1.5 1.5e-06 28.4 0.3 1.9 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein TPP_enzyme_M PF00205.22 EGR29706.1 - 0.027 14.2 0.0 0.061 13.1 0.0 1.6 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, central domain DUF364 PF04016.12 EGR29706.1 - 0.037 13.6 0.0 0.072 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative heavy-metal chelation zinc_ribbon_9 PF14369.6 EGR29706.1 - 1.5 9.2 5.9 0.65 10.3 0.3 2.7 3 1 0 3 3 3 0 zinc-ribbon Ribosomal_S13 PF00416.22 EGR29706.1 - 1.6 9.1 4.5 5.5 7.4 0.7 2.7 3 0 0 3 3 3 0 Ribosomal protein S13/S18 C1_2 PF03107.16 EGR29706.1 - 4.6 7.6 6.4 1 9.7 0.9 2.3 2 0 0 2 2 2 0 C1 domain Herpes_UL20 PF04544.12 EGR29709.1 - 0.33 11.3 8.4 0.43 10.9 8.4 1.1 1 0 0 1 1 1 0 Herpesvirus egress protein UL20 Ndc80_HEC PF03801.13 EGR29709.1 - 3.9 7.1 11.9 0.18 11.4 6.5 1.5 2 0 0 2 2 2 0 HEC/Ndc80p family Tubulin PF00091.25 EGR29710.1 - 3.2e-68 229.8 0.4 1.5e-67 227.6 0.1 2.0 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGR29710.1 - 1.3e-48 164.3 0.3 3e-48 163.1 0.3 1.6 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGR29710.1 - 9.8e-07 29.1 0.2 2.7e-06 27.7 0.0 1.8 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain HeH PF12949.7 EGR29710.1 - 0.045 13.5 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 HeH/LEM domain IF-2B PF01008.17 EGR29711.1 - 1e-58 198.8 0.5 2.7e-49 167.9 0.0 2.2 1 1 1 2 2 2 2 Initiation factor 2 subunit family APH PF01636.23 EGR29711.1 - 3.9e-14 53.2 0.0 7.1e-14 52.3 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGR29711.1 - 0.0002 21.0 0.2 0.00044 19.9 0.2 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH_6_hur PF04655.14 EGR29711.1 - 0.0098 15.3 0.0 0.022 14.2 0.0 1.5 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase Fructosamin_kin PF03881.14 EGR29711.1 - 0.012 14.8 0.1 0.036 13.3 0.0 1.8 3 0 0 3 3 3 0 Fructosamine kinase DUF1679 PF07914.11 EGR29711.1 - 0.02 13.8 0.0 0.044 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1679) RNase_Zc3h12a PF11977.8 EGR29711.1 - 0.07 12.9 0.1 0.23 11.2 0.1 1.8 1 0 0 1 1 1 0 Zc3h12a-like Ribonuclease NYN domain SNF PF00209.18 EGR29712.1 - 2.1e-64 218.1 23.4 1.2e-38 133.1 8.9 3.0 1 1 1 2 2 2 2 Sodium:neurotransmitter symporter family adh_short_C2 PF13561.6 EGR29713.1 - 8.3e-06 25.5 0.0 1.1e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGR29713.1 - 3.9e-05 23.2 0.0 5.5e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Vitellogenin_N PF01347.22 EGR29713.1 - 0.0076 14.7 1.3 0.0097 14.4 1.3 1.1 1 0 0 1 1 1 1 Lipoprotein amino terminal region Pkinase PF00069.25 EGR29714.1 - 3e-48 164.5 1.1 4.2e-48 164.0 1.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29714.1 - 9.4e-25 87.4 0.1 1.3e-24 86.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR29714.1 - 1.5e-05 25.0 0.0 3e-05 24.1 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGR29714.1 - 6.5e-05 22.6 0.6 0.00022 20.9 0.6 1.9 1 1 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EGR29714.1 - 0.00092 18.9 0.6 0.00092 18.9 0.6 2.2 2 1 0 2 2 2 1 Choline/ethanolamine kinase Kinase-like PF14531.6 EGR29714.1 - 0.0055 16.1 0.1 0.057 12.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like DUF4894 PF16235.5 EGR29714.1 - 0.054 13.9 4.0 0.48 10.8 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4894) MRP-L51 PF10244.9 EGR29714.1 - 0.061 13.5 0.1 0.18 12.1 0.0 1.8 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit XPG_I PF00867.18 EGR29715.1 - 1.1e-15 57.8 0.6 1.9e-13 50.6 0.1 2.2 2 0 0 2 2 2 2 XPG I-region XPG_N PF00752.17 EGR29715.1 - 3e-06 27.7 0.1 6.2e-06 26.6 0.1 1.5 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I_2 PF12813.7 EGR29715.1 - 1.5e-05 24.6 0.4 2.4e-05 24.0 0.2 1.4 1 1 0 1 1 1 1 XPG domain containing DUF4106 PF13388.6 EGR29715.1 - 0.047 12.9 0.1 0.058 12.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) T3RM_EcoP15I_C PF18273.1 EGR29715.1 - 0.097 13.0 0.4 4.3 7.7 0.0 2.1 1 1 1 2 2 2 0 Type III R-M EcoP15I C-terminal domain Lactamase_B_2 PF12706.7 EGR29716.1 - 7.4e-13 48.5 0.0 1.2e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 EGR29716.1 - 2.5e-11 43.1 2.0 9.4e-10 38.0 0.2 2.9 3 0 0 3 3 3 1 tRNase Z endonuclease Lactamase_B PF00753.27 EGR29716.1 - 0.00094 19.2 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily CHAP PF05257.16 EGR29718.1 - 4.9e-12 46.3 0.1 9.1e-12 45.4 0.1 1.5 1 0 0 1 1 1 1 CHAP domain ChapFlgA_N PF17656.1 EGR29718.1 - 0.031 14.4 0.0 0.058 13.6 0.0 1.4 1 0 0 1 1 1 0 FlgA N-terminal domain RimK PF08443.11 EGR29719.1 - 1.2e-18 67.4 0.0 1.8e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain GSH-S_ATP PF02955.16 EGR29719.1 - 2.5e-09 36.8 0.0 4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain ATP-grasp_3 PF02655.14 EGR29719.1 - 9.3e-09 35.5 0.0 1.6e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 EGR29719.1 - 3.5e-05 23.2 0.2 0.011 15.0 0.1 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp LAGLIDADG_1 PF00961.19 EGR29719.1 - 0.047 14.7 2.0 0.13 13.2 2.0 1.8 1 0 0 1 1 1 0 LAGLIDADG endonuclease Imm25 PF15564.6 EGR29719.1 - 0.1 12.5 0.1 0.1 12.5 0.1 2.5 3 0 0 3 3 3 0 Immunity protein 25 A_thal_3526 PF09713.10 EGR29719.1 - 0.16 12.3 0.8 1.6 9.0 0.1 2.8 3 0 0 3 3 3 0 Plant protein 1589 of unknown function (A_thal_3526) Ion_trans PF00520.31 EGR29721.1 - 1.4e-14 54.0 29.2 1.9e-14 53.5 29.2 1.1 1 0 0 1 1 1 1 Ion transport protein Polysacc_deac_3 PF15421.6 EGR29722.1 - 0.037 12.5 0.0 0.052 12.1 0.0 1.1 1 0 0 1 1 1 0 Putative polysaccharide deacetylase BBS1 PF14779.6 EGR29722.1 - 0.36 10.2 1.3 0.56 9.6 1.3 1.3 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 HEAT PF02985.22 EGR29723.1 - 4.5e-14 51.3 0.1 0.8 10.1 0.0 9.3 10 0 0 10 10 8 3 HEAT repeat HEAT_2 PF13646.6 EGR29723.1 - 3.5e-10 40.2 0.0 0.017 15.5 0.0 5.9 4 2 3 7 7 7 3 HEAT repeats Importin_rep_4 PF18808.1 EGR29723.1 - 5.9e-07 29.7 12.1 2.4e-06 27.7 0.0 5.1 6 0 0 6 6 6 1 Importin repeat HEAT_EZ PF13513.6 EGR29723.1 - 2.2e-05 24.8 0.0 16 6.1 0.0 6.2 5 1 1 6 6 6 0 HEAT-like repeat Cnd1 PF12717.7 EGR29723.1 - 0.00062 19.8 28.0 1.2 9.2 0.3 6.8 4 2 2 7 7 7 4 non-SMC mitotic condensation complex subunit 1 RTP1_C1 PF10363.9 EGR29723.1 - 0.055 13.7 7.4 20 5.4 0.3 4.7 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 EGR29723.1 - 0.07 13.2 1.7 16 5.7 0.1 5.0 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat ATC_hydrolase PF14196.6 EGR29723.1 - 0.98 10.2 2.8 4.4 8.1 0.8 3.0 3 0 0 3 3 3 0 L-2-amino-thiazoline-4-carboxylic acid hydrolase UME PF08064.13 EGR29723.1 - 1.3 9.0 8.9 5.7 6.9 0.1 5.3 5 1 1 6 6 6 0 UME (NUC010) domain UCH PF00443.29 EGR29723.1 - 2.8 7.4 13.0 37 3.7 0.0 4.4 2 2 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase Nop52 PF05997.12 EGR29723.1 - 3.3 7.5 13.6 0.053 13.3 0.4 4.1 3 3 1 4 4 4 0 Nucleolar protein,Nop52 GIT1_C PF12205.8 EGR29723.1 - 3.4 7.8 6.8 26 5.0 0.5 4.7 4 0 0 4 4 4 0 G protein-coupled receptor kinase-interacting protein 1 C term RasGEF_N_2 PF14663.6 EGR29723.1 - 3.7 8.0 8.6 2.5 8.6 0.1 4.7 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain SCIMP PF15050.6 EGR29724.1 - 0.00061 20.3 0.3 0.00071 20.0 0.3 1.1 1 0 0 1 1 1 1 SCIMP protein UCH PF00443.29 EGR29725.1 - 1.1e-44 152.9 3.3 1.1e-44 152.9 3.3 4.6 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR29725.1 - 6.7e-23 81.8 4.2 6.7e-23 81.8 4.2 3.8 2 2 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Agenet PF05641.12 EGR29726.1 - 0.00011 22.6 0.6 0.22 12.0 0.0 2.5 2 0 0 2 2 2 2 Agenet domain MBT PF02820.18 EGR29726.1 - 0.087 13.2 1.2 1.7 9.0 0.3 3.1 2 1 0 2 2 2 0 mbt repeat tRNA-synt_1c PF00749.21 EGR29727.1 - 4.4e-66 222.9 3.8 4.4e-66 222.9 3.8 2.2 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain FTCD_C PF04961.12 EGR29727.1 - 0.12 12.1 0.2 0.25 11.1 0.2 1.4 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase RRM_1 PF00076.22 EGR29728.1 - 5.1e-19 67.9 3.0 3.8e-13 49.0 0.8 2.5 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGR29728.1 - 0.00029 20.4 0.2 0.0014 18.3 0.1 1.8 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGR29728.1 - 0.003 17.4 0.1 0.14 12.0 0.0 2.3 1 1 1 2 2 2 1 Occluded RNA-recognition motif PHM7_cyt PF14703.6 EGR29728.1 - 0.015 15.6 0.4 0.13 12.5 0.1 2.1 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM_2 PF14605.6 EGR29728.1 - 0.022 14.8 0.1 7.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif SET_assoc PF11767.8 EGR29728.1 - 0.071 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated MORN PF02493.20 EGR29729.1 - 2.4e-55 181.2 81.9 1.5e-07 30.9 3.6 10.4 10 0 0 10 10 10 9 MORN repeat FliG_C PF01706.16 EGR29730.1 - 0.01 16.0 1.1 0.083 13.1 0.1 2.8 2 0 0 2 2 2 0 FliG C-terminal domain PsbT PF01405.17 EGR29732.1 - 0.026 14.3 4.3 0.053 13.3 4.3 1.4 1 0 0 1 1 1 0 Photosystem II reaction centre T protein Rpr2 PF04032.16 EGR29732.1 - 0.15 12.4 0.8 11 6.4 0.1 3.2 3 0 0 3 3 3 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DENN PF02141.21 EGR29733.1 - 2.2e-15 57.1 0.9 2.6e-15 56.9 0.9 1.0 1 0 0 1 1 1 1 DENN (AEX-3) domain Avl9 PF09794.9 EGR29733.1 - 0.0059 15.3 0.1 0.0061 15.3 0.1 1.1 1 0 0 1 1 1 1 Transport protein Avl9 MORN PF02493.20 EGR29734.1 - 6.5e-49 161.0 82.9 1.7e-08 33.9 2.0 10.3 10 0 0 10 10 10 10 MORN repeat CxC4 PF18717.1 EGR29734.1 - 1.9 8.4 5.7 15 5.4 0.1 3.1 3 0 0 3 3 3 0 CxC4 like cysteine cluster associated with KDZ transposases Tudor_2 PF18104.1 EGR29734.1 - 2.8 7.7 0.0 2.8 7.7 0.0 6.5 7 0 0 7 7 7 0 Jumonji domain-containing protein 2A Tudor domain Guanylate_cyc PF00211.20 EGR29735.1 - 1.8e-78 262.3 7.9 2e-41 141.6 2.1 2.6 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain E1-E2_ATPase PF00122.20 EGR29735.1 - 0.0029 17.1 0.1 0.0029 17.1 0.1 5.5 6 1 1 7 7 7 1 E1-E2 ATPase Na_Ca_ex PF01699.24 EGR29736.1 - 2.8e-15 56.6 10.7 3.6e-15 56.2 10.7 1.1 1 0 0 1 1 1 1 Sodium/calcium exchanger protein zf-B_box PF00643.24 EGR29737.1 - 0.0017 18.5 7.4 0.0036 17.4 7.4 1.5 1 0 0 1 1 1 1 B-box zinc finger DUF1631 PF07793.11 EGR29737.1 - 0.28 9.6 2.7 0.37 9.1 2.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) GLTP PF08718.11 EGR29737.1 - 0.34 11.2 5.2 6.4 7.0 1.9 2.5 1 1 1 2 2 2 0 Glycolipid transfer protein (GLTP) Allexi_40kDa PF05549.11 EGR29737.1 - 2.8 7.4 12.6 0.083 12.4 4.2 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF2203 PF09969.9 EGR29737.1 - 3.8 8.3 8.9 0.91 10.3 2.6 2.6 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Propeptide_C25 PF08126.11 EGR29738.1 - 0.12 11.5 2.0 0.13 11.3 0.6 1.7 2 0 0 2 2 2 0 Propeptide_C25 LRR_11 PF18831.1 EGR29738.1 - 0.12 11.9 0.6 1.3 8.7 0.1 2.6 2 0 0 2 2 2 0 Leucine-rich repeat Y_phosphatase PF00102.27 EGR29739.1 - 5.7e-57 193.0 8.9 5.7e-57 193.0 8.9 2.4 2 1 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGR29739.1 - 0.00038 20.6 1.9 0.00097 19.3 0.0 2.7 2 1 1 3 3 3 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EGR29739.1 - 0.014 15.4 0.0 0.038 14.0 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 EGR29739.1 - 0.015 15.1 3.2 0.021 14.7 0.0 2.9 2 0 0 2 2 2 0 Dual specificity phosphatase, catalytic domain ABC_tran PF00005.27 EGR29740.1 - 4.8e-42 143.7 12.6 1.1e-25 90.7 0.5 3.3 4 0 0 4 4 2 2 ABC transporter ABC_membrane PF00664.23 EGR29740.1 - 7.4e-31 107.8 48.2 9.1e-24 84.5 29.7 2.5 2 0 0 2 2 2 2 ABC transporter transmembrane region SMC_N PF02463.19 EGR29740.1 - 1.8e-08 34.1 24.5 8.5e-06 25.4 2.2 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGR29740.1 - 4e-06 26.9 5.4 0.0072 16.2 0.1 3.3 3 0 0 3 3 3 2 RsgA GTPase AAA_7 PF12775.7 EGR29740.1 - 0.00017 21.2 0.8 0.7 9.4 0.1 3.1 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_29 PF13555.6 EGR29740.1 - 0.00022 20.9 0.1 0.96 9.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGR29740.1 - 0.00029 21.2 0.0 0.14 12.5 0.0 2.8 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGR29740.1 - 0.0003 21.1 0.2 0.41 10.9 0.0 3.1 2 1 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGR29740.1 - 0.00031 20.8 0.6 1.6 8.9 0.2 3.3 2 1 0 2 2 2 2 50S ribosome-binding GTPase T2SSE PF00437.20 EGR29740.1 - 0.00057 19.0 0.0 0.51 9.3 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein NACHT PF05729.12 EGR29740.1 - 0.001 19.0 0.3 0.047 13.6 0.0 3.3 2 1 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.12 EGR29740.1 - 0.019 14.2 0.0 0.5 9.6 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 EGR29740.1 - 0.057 13.8 4.6 5.9 7.3 0.0 3.8 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) SMN PF06003.12 EGR29740.1 - 0.08 12.2 0.9 0.27 10.4 0.9 1.9 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) SbcCD_C PF13558.6 EGR29740.1 - 0.12 12.7 0.9 12 6.2 0.1 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 EGR29740.1 - 0.28 11.6 6.5 5.7 7.4 0.0 5.1 5 0 0 5 5 5 0 RNA helicase Roc PF08477.13 EGR29740.1 - 0.99 9.6 5.8 19 5.5 0.1 3.6 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EGR29740.1 - 3.3 7.7 20.5 3.5 7.6 0.9 5.6 5 1 0 5 5 5 0 Dynamin family GGA_N-GAT PF18308.1 EGR29741.1 - 0.032 13.8 1.0 0.1 12.2 1.0 1.8 1 0 0 1 1 1 0 GGA N-GAT domain Tfb5 PF06331.12 EGR29741.1 - 0.71 9.9 5.9 0.36 10.9 0.7 3.3 3 0 0 3 3 3 0 Transcription factor TFIIH complex subunit Tfb5 DUF4200 PF13863.6 EGR29743.1 - 3.5e-27 95.2 39.1 3.5e-27 95.2 39.1 3.3 2 1 0 2 2 2 1 Domain of unknown function (DUF4200) DivIC PF04977.15 EGR29743.1 - 0.00049 19.8 12.5 0.00049 19.8 12.5 5.1 1 1 3 5 5 5 1 Septum formation initiator ALAD PF00490.21 EGR29745.1 - 3.1e-114 381.4 0.0 3.7e-114 381.2 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase AsnC_trans_reg PF01037.21 EGR29745.1 - 0.047 13.7 0.0 0.36 10.8 0.0 2.4 2 1 1 3 3 3 0 Lrp/AsnC ligand binding domain EF-hand_1 PF00036.32 EGR29747.1 - 5.7e-07 28.6 2.7 3.7e-05 22.9 0.1 3.6 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 EGR29747.1 - 8.7e-07 29.3 6.1 0.002 18.6 0.7 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR29747.1 - 3.7e-06 26.4 5.2 0.00062 19.5 0.1 3.8 2 1 1 3 3 3 2 EF-hand domain Dockerin_1 PF00404.18 EGR29747.1 - 8.8e-05 22.6 2.2 0.15 12.3 1.3 2.4 2 0 0 2 2 2 2 Dockerin type I domain EF-hand_5 PF13202.6 EGR29747.1 - 0.00027 20.3 2.6 0.00055 19.3 0.1 2.7 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 EGR29747.1 - 0.0086 16.4 0.0 38 4.7 0.0 3.3 2 1 1 3 3 3 0 EF-hand domain SPARC_Ca_bdg PF10591.9 EGR29747.1 - 0.01 16.2 4.8 0.56 10.5 2.8 2.5 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 EGR29747.1 - 0.2 11.5 2.8 0.94 9.4 0.1 3.1 2 1 3 5 5 5 0 EF-hand domain pair Thiolase_N PF00108.23 EGR29748.1 - 7.8e-22 77.9 0.0 4.8e-21 75.3 0.0 2.1 2 1 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGR29748.1 - 5.8e-12 45.3 0.6 9.1e-10 38.2 0.0 2.8 2 1 1 3 3 3 2 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGR29748.1 - 0.00015 21.5 0.4 0.00049 19.8 0.4 1.8 1 1 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGR29748.1 - 0.00063 19.5 0.0 0.25 11.2 0.0 2.5 2 0 0 2 2 2 2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Ketoacyl-synt_C PF02801.22 EGR29748.1 - 0.0014 18.6 0.1 0.93 9.5 0.0 3.2 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain SpoVAD PF07451.11 EGR29748.1 - 0.021 13.6 0.2 0.052 12.3 0.0 1.7 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Pkinase PF00069.25 EGR29750.1 - 3.8e-55 187.1 4.8 5.1e-55 186.7 4.8 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29750.1 - 7.3e-28 97.5 0.5 1.2e-27 96.9 0.5 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29750.1 - 5.2e-07 29.3 2.6 0.0021 17.4 0.0 3.4 2 1 0 2 2 2 2 Kinase-like APH PF01636.23 EGR29750.1 - 0.038 13.9 0.0 0.49 10.3 0.2 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Inhibitor_G39P PF11417.8 EGR29750.1 - 0.091 13.3 0.1 0.3 11.6 0.1 1.8 1 0 0 1 1 1 0 Loader and inhibitor of phage G40P Peptidase_M49 PF03571.15 EGR29751.1 - 7.3e-204 678.2 12.3 9e-204 677.9 12.3 1.1 1 0 0 1 1 1 1 Peptidase family M49 MORN PF02493.20 EGR29752.1 - 8.7e-20 69.4 31.9 2.5e-07 30.2 1.3 7.3 7 0 0 7 7 7 5 MORN repeat MRP-S22 PF10245.9 EGR29752.1 - 0.0024 17.7 0.8 0.49 10.1 0.1 2.3 2 0 0 2 2 2 2 Mitochondrial 28S ribosomal protein S22 DUF3048_C PF17479.2 EGR29752.1 - 0.43 11.0 6.2 12 6.3 3.7 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3048) C-terminal domain Pkinase PF00069.25 EGR29753.1 - 1.5e-62 211.3 1.8 2.2e-62 210.8 1.8 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29753.1 - 1.1e-40 139.6 0.1 1.5e-40 139.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR29753.1 - 8.4e-06 24.8 0.2 1.4e-05 24.0 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGR29753.1 - 4.2e-05 23.0 0.4 9.3e-05 21.9 0.2 1.7 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 EGR29754.1 - 1.3e-70 237.8 0.3 1.6e-70 237.5 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29754.1 - 1.9e-39 135.5 0.1 2.3e-39 135.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29754.1 - 0.00023 20.6 0.2 0.081 12.2 0.0 2.4 2 1 0 2 2 2 2 Kinase-like APH PF01636.23 EGR29754.1 - 0.00057 19.9 0.0 0.0036 17.2 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGR29754.1 - 0.006 15.4 0.0 0.0073 15.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EGR29754.1 - 0.0065 16.1 1.3 1.3 8.6 0.6 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 DUF1463 PF07316.11 EGR29754.1 - 0.065 13.1 0.1 0.15 11.9 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1463) Mak16 PF04874.14 EGR29754.1 - 0.086 13.5 0.6 0.16 12.6 0.6 1.4 1 0 0 1 1 1 0 Mak16 protein C-terminal region Nucleoside_tran PF01733.18 EGR29756.1 - 4.8e-11 42.6 5.2 4.8e-11 42.6 5.2 3.2 2 2 2 4 4 4 1 Nucleoside transporter tRNA-synt_1 PF00133.22 EGR29757.1 - 3e-234 778.8 0.4 3e-234 778.8 0.4 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGR29757.1 - 2.5e-26 92.5 0.8 5.3e-26 91.4 0.8 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGR29757.1 - 5.7e-15 55.0 1.6 3e-06 26.2 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EGR29757.1 - 0.0084 15.5 0.0 0.0084 15.5 0.0 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain DUF737 PF05300.11 EGR29757.1 - 0.47 10.8 4.9 0.84 10.0 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF737) DUF5501 PF17605.2 EGR29758.1 - 0.0055 17.1 0.0 3.8 8.0 0.0 3.2 2 1 0 2 2 2 2 Family of unknown function (DUF5501) Nucleoside_tran PF01733.18 EGR29759.1 - 7.2e-16 58.4 18.9 2.3e-15 56.8 17.8 2.2 1 1 0 1 1 1 1 Nucleoside transporter DUF4411 PF14367.6 EGR29760.1 - 0.089 12.7 1.9 0.14 12.0 1.7 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4411) Nucleoside_tran PF01733.18 EGR29761.1 - 9.3e-09 35.1 1.4 9.3e-09 35.1 1.4 3.2 2 2 1 3 3 3 2 Nucleoside transporter Nucleoside_tran PF01733.18 EGR29762.1 - 2.3e-26 92.9 17.2 1.6e-25 90.2 17.2 2.0 1 1 0 1 1 1 1 Nucleoside transporter SHIPPO-rpt PF07004.12 EGR29763.1 - 2e-06 28.4 29.2 0.0028 18.5 0.1 7.0 8 1 0 8 8 8 4 Sperm-tail PG-rich repeat FlxA PF14282.6 EGR29764.1 - 0.0056 16.7 7.3 0.0056 16.7 7.3 3.4 2 1 1 3 3 3 1 FlxA-like protein EHN PF06441.12 EGR29764.1 - 0.008 16.5 0.1 0.13 12.7 0.1 2.8 1 1 0 1 1 1 1 Epoxide hydrolase N terminus SHE3 PF17078.5 EGR29764.1 - 0.15 11.8 37.1 0.79 9.4 20.2 3.4 1 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 Spc7 PF08317.11 EGR29764.1 - 0.43 9.4 30.4 0.23 10.3 15.7 2.6 2 1 0 2 2 2 0 Spc7 kinetochore protein THOC7 PF05615.13 EGR29764.1 - 0.59 10.4 24.8 6.7 7.0 17.4 3.0 2 1 0 2 2 2 0 Tho complex subunit 7 ABC_tran_CTD PF16326.5 EGR29764.1 - 0.76 10.1 26.9 0.71 10.2 0.3 4.2 4 0 0 4 4 4 0 ABC transporter C-terminal domain DUF3641 PF12345.8 EGR29764.1 - 1.7 8.7 7.8 6.1 6.9 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3641) DUF1664 PF07889.12 EGR29764.1 - 2.9 7.9 23.7 0.56 10.2 2.4 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF1664) Filament PF00038.21 EGR29764.1 - 3.8 7.0 32.6 0.18 11.3 5.9 2.8 2 1 0 2 2 2 0 Intermediate filament protein DUF948 PF06103.11 EGR29764.1 - 8 6.8 8.6 5 7.5 0.4 3.3 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Peptidase_S9 PF00326.21 EGR29765.1 - 1.4e-34 119.4 0.0 4.8e-34 117.7 0.0 1.7 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EGR29765.1 - 3.1e-08 33.6 1.7 5.2e-07 29.6 0.6 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGR29765.1 - 1.7e-07 32.1 0.0 2.7e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGR29765.1 - 2.6e-07 30.2 0.0 7.7e-05 22.1 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 COesterase PF00135.28 EGR29765.1 - 0.00018 20.5 0.0 0.00024 20.1 0.0 1.2 1 0 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 EGR29765.1 - 0.00053 19.6 0.0 0.036 13.6 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family DUF2920 PF11144.8 EGR29765.1 - 0.0023 17.2 0.2 0.0043 16.3 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) UPF0227 PF05728.12 EGR29765.1 - 0.0029 17.6 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_3 PF07859.13 EGR29765.1 - 0.0041 17.0 0.0 0.0072 16.2 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EGR29765.1 - 0.0097 15.7 0.6 0.57 9.9 0.1 2.5 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 EGR29765.1 - 0.014 15.1 0.0 0.031 14.0 0.0 1.5 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Esterase_phd PF10503.9 EGR29765.1 - 0.032 13.7 0.0 0.059 12.9 0.0 1.3 1 0 0 1 1 1 0 Esterase PHB depolymerase Phage_lysozyme PF00959.19 EGR29766.1 - 0.13 12.7 3.5 0.14 12.6 2.7 1.4 1 1 0 1 1 1 0 Phage lysozyme PIP5K PF01504.18 EGR29767.1 - 4.9e-61 206.3 15.2 4.9e-61 206.3 15.2 3.6 3 1 0 3 3 3 1 Phosphatidylinositol-4-phosphate 5-Kinase EF-hand_8 PF13833.6 EGR29767.1 - 5.6e-08 32.5 9.9 7.2e-05 22.6 1.1 3.0 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_7 PF13499.6 EGR29767.1 - 8.9e-08 32.5 9.7 6.4e-05 23.3 0.5 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR29767.1 - 4.1e-06 26.0 13.5 0.0036 16.7 0.7 4.0 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 EGR29767.1 - 9.1e-05 22.1 11.5 0.0092 15.8 0.5 4.2 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.6 EGR29767.1 - 0.0022 17.4 7.9 0.0035 16.8 0.4 3.3 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 EGR29767.1 - 0.02 15.2 0.1 0.74 10.2 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain EF-hand_4 PF12763.7 EGR29767.1 - 0.033 14.1 12.4 0.49 10.4 0.5 3.6 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Sororin PF09666.10 EGR29767.1 - 0.15 12.2 2.7 2.9 8.1 0.1 2.4 2 0 0 2 2 2 0 Sororin protein Peptidase_M8 PF01457.16 EGR29768.1 - 6.8e-44 150.4 5.1 3.1e-41 141.7 0.0 2.5 2 1 1 3 3 3 2 Leishmanolysin EGF_2 PF07974.13 EGR29768.1 - 7.3e-05 23.1 12.3 7.3e-05 23.1 12.3 5.4 3 2 0 3 3 3 1 EGF-like domain EGF_Tenascin PF18720.1 EGR29768.1 - 0.00036 20.5 7.1 0.00036 20.5 7.1 2.8 3 0 0 3 3 3 1 Tenascin EGF domain DUF4116 PF13475.6 EGR29768.1 - 5.1 6.9 7.3 2.4 7.9 0.0 3.6 4 1 0 4 4 4 0 Domain of unknown function (DUF4116) Peptidase_M8 PF01457.16 EGR29770.1 - 0.00012 20.9 0.0 0.00014 20.7 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Act-Frag_cataly PF09192.10 EGR29772.1 - 6e-101 337.5 2.6 6e-101 337.5 2.6 2.8 2 1 1 3 3 3 2 Actin-fragmin kinase, catalytic LIN52 PF10044.9 EGR29772.1 - 5.1 7.9 9.0 0.57 10.9 0.4 3.0 2 1 1 3 3 3 0 Retinal tissue protein Redoxin PF08534.10 EGR29773.1 - 4e-30 104.5 0.0 4.5e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EGR29773.1 - 1.6e-14 53.9 0.0 1.9e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family DUF2469 PF10611.9 EGR29773.1 - 0.12 13.0 0.0 0.23 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2469) MORN PF02493.20 EGR29774.1 - 0.0072 16.2 0.2 0.22 11.5 0.3 2.3 2 0 0 2 2 2 1 MORN repeat Ribosomal_S6e PF01092.19 EGR29775.1 - 6.6e-54 181.2 4.7 8.2e-54 180.9 0.6 2.4 2 0 0 2 2 2 1 Ribosomal protein S6e Methyltransf_31 PF13847.6 EGR29777.1 - 3.6e-05 23.6 0.1 3.9e-05 23.5 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGR29777.1 - 5.2e-05 23.8 0.0 7.1e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGR29777.1 - 0.052 14.2 0.0 0.093 13.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DAO PF01266.24 EGR29780.1 - 1.5e-32 113.6 0.0 1.9e-20 73.7 0.0 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 EGR29780.1 - 3.1e-07 29.9 0.0 6.9e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EGR29780.1 - 4.7e-06 25.9 0.1 0.00011 21.4 0.1 2.1 2 0 0 2 2 2 1 FAD binding domain NAD_binding_8 PF13450.6 EGR29780.1 - 5.5e-06 26.5 0.1 2.4e-05 24.4 0.1 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGR29780.1 - 0.00011 21.6 0.0 0.00023 20.5 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGR29780.1 - 0.001 17.8 0.4 0.0028 16.4 0.1 1.8 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.12 EGR29780.1 - 0.0024 17.0 0.1 0.0036 16.4 0.1 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.6 EGR29780.1 - 0.0026 17.1 2.0 0.017 14.4 0.5 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGR29780.1 - 0.009 15.4 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase GMC_oxred_N PF00732.19 EGR29780.1 - 0.023 14.1 0.0 0.61 9.4 0.0 2.1 2 0 0 2 2 2 0 GMC oxidoreductase Pyr_redox PF00070.27 EGR29780.1 - 0.026 15.1 0.2 0.091 13.3 0.1 2.1 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 EGR29780.1 - 0.051 12.1 0.1 0.36 9.3 0.0 2.0 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.19 EGR29780.1 - 0.17 11.1 0.1 0.3 10.3 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain EF-hand_1 PF00036.32 EGR29782.1 - 2.2e-24 83.1 17.4 4.4e-07 29.0 0.1 5.9 6 0 0 6 6 6 3 EF hand EF-hand_6 PF13405.6 EGR29782.1 - 5.4e-23 78.9 13.1 8.4e-06 25.3 0.1 6.2 6 0 0 6 6 6 3 EF-hand domain EF-hand_5 PF13202.6 EGR29782.1 - 1.9e-19 68.2 15.4 1.9e-05 23.9 0.4 5.3 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 EGR29782.1 - 2.6e-18 66.2 14.7 2.9e-12 46.8 1.6 3.9 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.6 EGR29782.1 - 1.4e-16 60.0 8.4 9.4e-05 22.2 0.3 4.9 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_4 PF12763.7 EGR29782.1 - 5.9e-05 23.0 10.9 0.0083 16.1 0.5 3.6 1 1 1 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EGR29782.1 - 6.4e-05 22.7 11.8 0.027 14.3 0.8 4.7 4 1 1 5 5 5 3 EF hand EF-hand_9 PF14658.6 EGR29782.1 - 0.00018 21.7 0.0 0.09 13.1 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EGR29782.1 - 0.00056 20.2 3.4 0.0032 17.8 0.2 2.6 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_2 PF09068.11 EGR29782.1 - 0.015 15.5 1.7 0.051 13.7 0.2 2.4 2 1 0 2 2 2 0 EF hand CH_2 PF06294.11 EGR29782.1 - 0.061 13.4 0.1 0.2 11.8 0.1 2.0 1 0 0 1 1 1 0 CH-like domain in sperm protein Cbl_N2 PF02761.14 EGR29782.1 - 0.27 12.0 4.4 0.48 11.2 0.3 3.0 3 1 1 4 4 4 0 CBL proto-oncogene N-terminus, EF hand-like domain Ribosomal_S3Ae PF01015.18 EGR29783.1 - 4.9e-77 258.1 4.6 5.8e-77 257.8 4.6 1.0 1 0 0 1 1 1 1 Ribosomal S3Ae family Luciferase_N PF05295.11 EGR29783.1 - 0.061 13.3 0.3 0.13 12.3 0.3 1.6 1 1 0 1 1 1 0 Luciferase/LBP N-terminal domain zf-SAP30 PF13866.6 EGR29783.1 - 0.083 13.0 1.7 0.25 11.5 1.1 2.2 2 0 0 2 2 2 0 SAP30 zinc-finger CRAL_TRIO PF00650.20 EGR29784.1 - 8e-34 116.7 1.6 1.6e-33 115.7 1.6 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CCSMST1 PF15013.6 EGR29784.1 - 0.0039 17.3 0.4 0.021 15.0 0.0 2.2 2 0 0 2 2 2 1 CCSMST1 family RRM_1 PF00076.22 EGR29785.1 - 4.9e-20 71.1 0.2 2.1e-18 65.9 0.1 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGR29785.1 - 0.0039 16.8 0.0 0.0061 16.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGR29785.1 - 0.073 13.2 0.2 1.1 9.4 0.0 2.6 2 2 0 2 2 2 0 RNA recognition motif DnaJ PF00226.31 EGR29786.1 - 6.6e-23 80.6 5.4 4.4e-22 78.0 2.5 3.0 2 0 0 2 2 2 1 DnaJ domain Sec63 PF02889.16 EGR29786.1 - 3.1e-21 75.7 3.4 5.6e-21 74.9 3.4 1.4 1 0 0 1 1 1 1 Sec63 Brl domain Endosulfine PF04667.17 EGR29786.1 - 0.003 17.7 4.9 0.003 17.7 4.9 2.9 2 0 0 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region DUF4577 PF15145.6 EGR29786.1 - 0.016 15.3 0.5 8 6.5 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4577) RNA_pol_Rpc4 PF05132.14 EGR29786.1 - 0.2 12.0 7.1 0.47 10.9 7.1 1.6 1 0 0 1 1 1 0 RNA polymerase III RPC4 PPL5 PF18168.1 EGR29786.1 - 1.9 7.7 9.1 3.6 6.8 9.1 1.4 1 0 0 1 1 1 0 Prim-pol family 5 Tiam_CC_Ex PF18385.1 EGR29786.1 - 9.7 6.7 7.8 81 3.7 0.1 3.0 2 0 0 2 2 2 0 T-lymphoma invasion and metastasis CC-Ex domain LTP_2 PF14368.6 EGR29788.1 - 0.099 12.8 3.3 0.068 13.3 1.3 1.8 2 0 0 2 2 2 0 Probable lipid transfer Response_reg PF00072.24 EGR29789.1 - 1.1e-13 51.3 0.1 1.8e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 Response regulator receiver domain PCNA_C PF02747.15 EGR29791.1 - 4e-51 172.5 0.1 9.5e-48 161.6 0.0 2.1 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 EGR29791.1 - 2.2e-45 153.4 0.2 4.2e-45 152.6 0.2 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.16 EGR29791.1 - 9.4e-08 31.4 2.1 1.6e-05 24.2 2.1 2.2 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 EGR29791.1 - 5.4e-07 29.3 0.2 7.4e-07 28.9 0.2 1.2 1 0 0 1 1 1 1 Rad9 F_actin_cap_B PF01115.17 EGR29792.1 - 3.1e-82 275.8 0.1 3.9e-82 275.5 0.1 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Nup35_RRM_2 PF14605.6 EGR29792.1 - 0.078 13.0 0.0 1.2 9.2 0.0 2.6 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Metallophos PF00149.28 EGR29793.1 - 1.2e-35 123.9 0.7 1.7e-35 123.4 0.7 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Sof1 PF04158.14 EGR29793.1 - 0.72 10.2 5.1 1.3 9.3 2.5 2.2 2 0 0 2 2 2 0 Sof1-like domain Beta_propel PF09826.9 EGR29794.1 - 0.0023 16.9 1.9 0.017 14.0 0.1 2.2 2 0 0 2 2 2 2 Beta propeller domain PHD PF00628.29 EGR29795.1 - 4.4e-13 48.9 27.8 1.4e-12 47.3 7.2 3.2 2 1 1 3 3 3 2 PHD-finger LZ3wCH PF18517.1 EGR29795.1 - 0.0015 18.6 1.8 0.0015 18.6 1.8 2.3 3 0 0 3 3 3 1 Leucine zipper with capping helix domain PriA_CRR PF18319.1 EGR29795.1 - 0.003 17.5 2.7 0.37 10.8 0.8 3.2 2 0 0 2 2 2 1 PriA DNA helicase Cys-rich region (CRR) domain Prok-RING_1 PF14446.6 EGR29795.1 - 0.009 15.9 22.7 0.011 15.7 2.3 3.8 3 1 0 3 3 3 2 Prokaryotic RING finger family 1 zf-RING_9 PF13901.6 EGR29795.1 - 0.03 14.3 31.7 0.13 12.2 19.2 2.8 1 1 2 3 3 3 0 Putative zinc-RING and/or ribbon zf-RING_2 PF13639.6 EGR29795.1 - 0.047 14.0 27.1 1.7 9.0 8.7 3.5 1 1 2 3 3 3 0 Ring finger domain Zf_RING PF16744.5 EGR29795.1 - 0.051 13.7 4.3 0.051 13.7 4.3 3.5 1 1 2 3 3 3 0 KIAA1045 RING finger C1_1 PF00130.22 EGR29795.1 - 3.3 7.7 31.0 0.18 11.7 2.2 4.0 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_ribbon_17 PF17120.5 EGR29795.1 - 4.7 6.9 17.6 1.5 8.5 3.2 3.4 3 1 0 3 3 3 0 Zinc-ribbon, C4HC2 type ADK_lid PF05191.14 EGR29795.1 - 6.7 6.8 21.1 0.14 12.2 2.9 3.4 4 0 0 4 4 4 0 Adenylate kinase, active site lid SET PF00856.28 EGR29796.1 - 1.2e-08 35.5 0.1 5.5e-06 26.9 0.1 2.1 1 1 0 1 1 1 1 SET domain zf-C2H2 PF00096.26 EGR29797.1 - 0.0018 18.6 0.3 0.0018 18.6 0.3 2.0 2 0 0 2 2 2 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGR29797.1 - 0.013 16.3 0.3 0.013 16.3 0.3 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf_Hakai PF18408.1 EGR29797.1 - 0.025 14.3 0.8 0.12 12.1 0.1 2.2 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain zf-Di19 PF05605.12 EGR29797.1 - 0.048 14.0 0.1 0.095 13.0 0.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding CH PF00307.31 EGR29798.1 - 8.3e-12 45.3 0.2 8.3e-12 45.3 0.2 2.7 1 1 2 3 3 3 1 Calponin homology (CH) domain MOZART2 PF12926.7 EGR29798.1 - 0.032 13.9 0.3 5.1 6.8 0.3 2.3 2 0 0 2 2 2 0 Mitotic-spindle organizing gamma-tubulin ring associated CAMSAP_CH PF11971.8 EGR29798.1 - 0.069 13.0 0.4 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 CAMSAP CH domain DUF5349 PF17298.2 EGR29798.1 - 1.8 8.2 12.9 2.4 7.9 12.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Pkinase PF00069.25 EGR29799.1 - 9.5e-63 212.0 0.0 1.4e-62 211.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29799.1 - 2.1e-32 112.5 0.0 3.2e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29799.1 - 9e-08 31.8 0.0 1.3e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGR29799.1 - 0.0029 16.6 0.4 0.0043 16.0 0.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain DUF676 PF05057.14 EGR29800.1 - 4.2e-42 144.1 0.4 1.4e-41 142.4 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) DUF3657 PF12394.8 EGR29800.1 - 1.8e-21 76.5 1.2 1.8e-21 76.5 1.2 3.0 3 0 0 3 3 3 1 Protein FAM135 PGAP1 PF07819.13 EGR29800.1 - 0.0007 19.4 1.6 0.0013 18.5 0.1 2.3 2 1 0 2 2 2 1 PGAP1-like protein Hydrolase_4 PF12146.8 EGR29800.1 - 0.11 11.8 0.0 0.33 10.2 0.0 1.8 1 0 0 1 1 1 0 Serine aminopeptidase, S33 LRR_8 PF13855.6 EGR29801.1 - 5.3e-12 45.3 28.7 1.2e-06 28.2 9.8 5.1 1 1 4 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 EGR29801.1 - 6.2e-10 38.8 10.0 8.6e-07 28.6 3.1 2.7 1 1 2 3 3 3 2 Leucine-rich repeat LRR_4 PF12799.7 EGR29801.1 - 1.4e-08 34.9 34.9 0.00017 21.9 8.7 5.3 2 2 5 7 7 7 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGR29801.1 - 0.00022 21.0 11.8 5.4 7.3 0.2 7.1 7 1 1 8 8 8 2 Leucine Rich repeat TbpB_C PF17483.2 EGR29801.1 - 0.06 13.7 7.9 9 6.7 0.8 3.6 2 1 1 3 3 3 0 C-lobe handle domain of Tf-binding protein B FAM47 PF14642.6 EGR29801.1 - 0.18 11.3 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 FAM47 family LRR_1 PF00560.33 EGR29801.1 - 0.43 11.3 25.5 22 6.1 0.3 7.6 7 1 1 8 8 8 0 Leucine Rich Repeat Autophagy_N PF03986.13 EGR29802.1 - 1.3e-28 99.7 0.6 1.8e-28 99.2 0.6 1.2 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 EGR29802.1 - 5.5e-16 58.9 0.6 1.2e-15 57.9 0.6 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 EGR29802.1 - 9.5e-13 47.4 0.2 2e-12 46.4 0.2 1.6 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal DUF3294 PF07957.11 EGR29804.1 - 0.0041 16.9 0.6 0.01 15.6 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3294) GBR_NSP5 PF17580.2 EGR29804.1 - 0.012 15.4 0.3 0.012 15.4 0.3 1.5 2 0 0 2 2 2 0 Group B Rotavirus Non-structural protein 5 PP2C PF00481.21 EGR29805.1 - 5.9e-44 150.6 0.1 1.6e-43 149.2 0.0 1.8 2 1 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGR29805.1 - 0.04 13.6 0.0 0.076 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase 2C Clathrin PF00637.20 EGR29807.1 - 1.3e-22 80.2 51.3 8.4e-06 25.7 1.8 11.5 6 4 4 11 11 11 7 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 EGR29807.1 - 1e-13 51.4 2.2 0.084 13.2 0.0 5.8 4 3 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain TPR_7 PF13176.6 EGR29807.1 - 1e-07 31.5 26.6 1.2 9.3 0.1 11.7 12 1 1 13 13 12 4 Tetratricopeptide repeat WD40 PF00400.32 EGR29807.1 - 5e-07 30.3 1.1 4.8 8.2 0.1 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EGR29807.1 - 7.2e-07 28.6 2.1 7.2e-07 28.6 2.1 6.6 6 3 4 10 10 10 1 Coatomer WD associated region eIF2A PF08662.11 EGR29807.1 - 3.7e-05 23.7 8.8 0.028 14.3 0.9 4.3 4 1 0 4 4 4 2 Eukaryotic translation initiation factor eIF2A PPR PF01535.20 EGR29807.1 - 0.017 15.3 15.9 8.3 6.9 0.3 8.3 8 1 1 9 9 9 0 PPR repeat TPR_12 PF13424.6 EGR29807.1 - 0.11 12.7 27.8 17 5.8 0.4 11.1 7 3 3 11 11 11 0 Tetratricopeptide repeat PPR_2 PF13041.6 EGR29807.1 - 0.19 12.0 17.6 6.2 7.1 0.1 7.7 8 0 0 8 8 8 0 PPR repeat family Glyco_transf_8C PF08437.10 EGR29807.1 - 0.88 9.7 4.2 19 5.4 0.1 4.3 4 0 0 4 4 4 0 Glycosyl transferase family 8 C-terminal Phage_Cox PF10743.9 EGR29807.1 - 0.91 9.7 7.6 16 5.7 0.0 4.6 5 0 0 5 5 5 0 Regulatory phage protein cox DUF3837 PF12939.7 EGR29807.1 - 4.5 7.7 9.6 5.2 7.5 0.3 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3837) RuvB_C PF05491.13 EGR29809.1 - 0.073 13.0 0.2 0.22 11.4 0.2 1.8 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain Cnd1_N PF12922.7 EGR29809.1 - 1.2 9.0 6.5 1.9 8.3 6.5 1.3 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1, N-term DUF3498 PF12004.8 EGR29809.1 - 6.7 5.8 11.9 8.6 5.4 11.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) His_Phos_2 PF00328.22 EGR29811.1 - 8.3e-18 64.9 0.2 1.1e-14 54.6 0.0 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) Mannosyl_trans PF05007.13 EGR29811.1 - 5.3e-15 56.0 28.2 2.1e-14 54.0 28.2 1.9 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) ThiF PF00899.21 EGR29812.1 - 2.3e-65 220.4 0.1 3.3e-65 219.8 0.1 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 EGR29812.1 - 2e-09 37.4 0.3 4.9e-09 36.2 0.2 1.7 2 0 0 2 2 2 1 E2 binding domain Shikimate_DH PF01488.20 EGR29812.1 - 8.2e-05 22.7 1.0 0.00056 20.0 0.1 2.3 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EGR29812.1 - 0.052 14.0 0.1 0.33 11.4 0.0 2.2 1 1 1 2 2 2 0 Putative NAD(P)-binding Ecm33 PF12454.8 EGR29812.1 - 0.15 12.3 1.7 0.31 11.2 1.7 1.6 1 0 0 1 1 1 0 GPI-anchored cell wall organization protein Pyr_redox PF00070.27 EGR29812.1 - 0.17 12.5 0.1 0.38 11.4 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 EGR29813.1 - 1.6e-45 155.5 0.4 2.6e-45 154.9 0.4 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29813.1 - 7e-36 123.8 0.0 1e-35 123.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1241 PF06840.11 EGR29813.1 - 9.2e-06 25.4 0.0 2.1e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1241) Kinase-like PF14531.6 EGR29813.1 - 0.0014 18.0 0.0 0.0044 16.4 0.0 1.8 1 1 0 1 1 1 1 Kinase-like RhoGEF PF00621.20 EGR29813.1 - 0.0027 18.0 2.9 0.004 17.4 2.9 1.2 1 0 0 1 1 1 1 RhoGEF domain Kdo PF06293.14 EGR29813.1 - 0.0041 16.5 0.0 0.006 16.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR29813.1 - 0.0058 15.4 0.1 0.0085 14.9 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase IL4 PF00727.18 EGR29813.1 - 0.027 14.7 0.9 0.068 13.4 0.2 2.0 2 0 0 2 2 2 0 Interleukin 4 R-HINP1I PF11463.8 EGR29813.1 - 0.043 13.3 0.4 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 R.HinP1I restriction endonuclease HutP PF09021.11 EGR29813.1 - 0.15 12.4 0.0 0.26 11.6 0.0 1.3 1 0 0 1 1 1 0 HutP PriX PF18689.1 EGR29813.1 - 0.16 12.4 0.2 0.16 12.4 0.2 2.2 3 0 0 3 3 3 0 Primase X T3RM_EcoP15I_C PF18273.1 EGR29813.1 - 0.2 12.0 3.2 0.13 12.6 0.6 2.2 2 1 1 3 3 3 0 Type III R-M EcoP15I C-terminal domain MCC-bdg_PDZ PF10506.9 EGR29814.1 - 0.037 14.0 3.5 0.051 13.6 3.6 1.4 1 1 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome SecA_PP_bind PF01043.20 EGR29814.1 - 0.067 13.8 1.1 0.072 13.7 1.1 1.1 1 0 0 1 1 1 0 SecA preprotein cross-linking domain Root_cap PF06830.11 EGR29815.1 - 0.041 14.0 0.0 0.054 13.6 0.0 1.2 1 0 0 1 1 1 0 Root cap CRAL_TRIO PF00650.20 EGR29816.1 - 6.9e-18 64.9 0.8 6.9e-18 64.9 0.8 1.7 2 0 0 2 2 2 1 CRAL/TRIO domain DUF2680 PF10925.8 EGR29816.1 - 0.019 15.0 0.1 0.019 15.0 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2680) CRAL_TRIO_2 PF13716.6 EGR29816.1 - 0.067 13.3 0.2 0.13 12.4 0.2 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain RRM_1 PF00076.22 EGR29817.1 - 2.4e-22 78.5 0.2 1.4e-15 56.8 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGR29817.1 - 9.7e-06 25.6 3.8 0.078 13.1 0.0 3.6 3 1 0 3 3 3 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EGR29817.1 - 0.056 13.5 0.1 0.56 10.2 0.0 2.2 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif PP2C PF00481.21 EGR29818.1 - 7.8e-49 166.6 0.0 1.3e-48 165.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.25 EGR29818.1 - 2.8e-21 76.1 0.0 6e-21 75.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29818.1 - 6.5e-07 28.9 0.1 2.2e-06 27.1 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase SpoIIE PF07228.12 EGR29818.1 - 0.00032 20.7 0.0 0.12 12.3 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EGR29818.1 - 0.00054 19.7 0.0 0.0039 16.9 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C ASPRs PF17641.2 EGR29818.1 - 0.67 10.3 3.7 2.1 8.6 0.1 3.0 2 2 0 2 2 2 0 Ancylostoma-associated secreted protein related LPP20 PF02169.16 EGR29818.1 - 0.71 10.3 6.7 0.095 13.1 0.8 2.5 3 0 0 3 3 3 0 LPP20 lipoprotein Memo PF01875.17 EGR29819.1 - 4.2e-71 239.2 1.0 5.2e-71 238.9 1.0 1.1 1 0 0 1 1 1 1 Memo-like protein Nepo_coat_C PF03688.14 EGR29819.1 - 0.093 12.6 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain RNA_pol_L_2 PF13656.6 EGR29821.1 - 5.8e-27 93.3 0.0 8.5e-27 92.7 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EGR29821.1 - 1.8e-07 30.5 0.0 2.8e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF4637 PF15470.6 EGR29821.1 - 0.042 13.6 2.8 0.049 13.3 2.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF3304 PF11745.8 EGR29821.1 - 0.38 11.2 2.2 20 5.6 2.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3304) PIH1_CS PF18201.1 EGR29822.1 - 1.5e-09 38.2 0.0 2.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 PIH1 CS-like domain PBECR4 PF18813.1 EGR29822.1 - 0.026 14.7 1.0 0.062 13.5 1.0 1.7 1 1 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease4 FAM199X PF15814.5 EGR29822.1 - 0.047 12.7 0.6 0.06 12.4 0.6 1.2 1 0 0 1 1 1 0 Protein family FAM199X CDKN3 PF05706.12 EGR29822.1 - 0.1 12.3 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) adh_short PF00106.25 EGR29823.1 - 9.8e-05 21.9 0.0 0.00012 21.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGR29823.1 - 0.00045 19.8 0.1 0.00051 19.7 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Dynein_light PF01221.18 EGR29824.1 - 2.2e-21 76.0 0.1 2.9e-21 75.6 0.1 1.1 1 0 0 1 1 1 1 Dynein light chain type 1 Pkinase PF00069.25 EGR29825.1 - 6.3e-70 235.5 0.0 7.5e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29825.1 - 9.4e-34 116.9 0.0 1.1e-33 116.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29825.1 - 0.00069 19.0 0.0 0.00098 18.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR29825.1 - 0.0065 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR29825.1 - 0.039 13.9 0.0 1.4 8.8 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family HTH_32 PF13565.6 EGR29825.1 - 0.17 12.5 0.0 0.38 11.4 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Baculo_PEP_C PF04513.12 EGR29826.1 - 0.0019 18.3 30.7 0.4 10.7 4.0 6.4 3 1 3 6 6 6 2 Baculovirus polyhedron envelope protein, PEP, C terminus ApoLp-III PF07464.11 EGR29826.1 - 0.22 11.6 0.0 0.22 11.6 0.0 6.8 3 1 4 7 7 7 0 Apolipophorin-III precursor (apoLp-III) DUF883 PF05957.13 EGR29826.1 - 0.41 11.3 3.6 18 6.0 0.0 4.2 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EGR29826.1 - 0.59 10.7 26.9 5.9 7.5 0.3 6.7 5 1 0 5 5 5 0 YtxH-like protein IF2_N PF04760.15 EGR29826.1 - 3.2 7.7 7.7 53 3.7 0.4 3.9 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region Guanylate_cyc PF00211.20 EGR29827.1 - 2.2e-55 187.1 7.4 1.3e-38 132.4 2.2 2.1 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF2652 PF10851.8 EGR29827.1 - 0.012 15.7 0.5 1.7 8.8 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2652) MIR PF02815.19 EGR29828.1 - 0.0018 18.1 0.2 0.0025 17.7 0.2 1.5 1 1 0 1 1 1 1 MIR domain MaoC_dehydratas PF01575.19 EGR29828.1 - 0.049 13.2 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 MaoC like domain POT1 PF02765.17 EGR29828.1 - 0.17 11.7 2.8 0.7 9.7 0.4 2.6 1 1 1 3 3 3 0 Telomeric single stranded DNA binding POT1/CDC13 Peptidase_M24 PF00557.24 EGR29829.1 - 1.1e-20 74.3 0.0 1.5e-20 73.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creb_binding PF09030.10 EGR29829.1 - 0.21 12.3 0.8 2.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Creb binding Piwi PF02171.17 EGR29830.1 - 4.3e-56 190.4 8.7 1e-55 189.1 8.7 1.7 1 0 0 1 1 1 1 Piwi domain PAZ PF02170.22 EGR29830.1 - 1.2e-15 57.5 5.7 6.6e-15 55.1 5.7 2.3 1 1 0 1 1 1 1 PAZ domain ArgoMid PF16487.5 EGR29830.1 - 0.24 11.7 7.4 0.56 10.5 0.4 3.6 3 0 0 3 3 3 0 Mid domain of argonaute PA PF02225.22 EGR29831.1 - 4.1e-05 23.5 0.0 7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 PA domain Metallophos PF00149.28 EGR29832.1 - 3.7e-38 132.1 0.6 4.8e-38 131.7 0.6 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGR29832.1 - 0.038 14.2 0.0 0.057 13.6 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Pkinase PF00069.25 EGR29833.1 - 8.2e-18 64.7 1.4 8.2e-18 64.7 1.4 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29833.1 - 3.1e-17 62.7 0.4 3.1e-17 62.7 0.4 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase ATP-grasp_2 PF08442.10 EGR29834.1 - 7.6e-32 110.5 1.4 1.8e-31 109.3 0.1 2.0 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 EGR29834.1 - 3.4e-16 59.4 1.1 6.7e-16 58.5 1.1 1.5 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 EGR29834.1 - 0.05 13.4 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain WD40 PF00400.32 EGR29835.1 - 3.6e-19 68.8 0.4 2.1e-06 28.3 0.1 6.5 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR29835.1 - 2.9e-06 27.5 0.6 0.075 13.3 0.0 5.5 5 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain HELP PF03451.14 EGR29835.1 - 0.02 14.7 0.0 0.059 13.2 0.0 1.9 2 0 0 2 2 2 0 HELP motif DUF4200 PF13863.6 EGR29835.1 - 0.073 13.5 0.3 0.073 13.5 0.3 5.7 3 2 2 5 5 5 0 Domain of unknown function (DUF4200) Fez1 PF06818.15 EGR29835.1 - 0.14 12.6 52.9 0.014 15.8 17.7 3.8 1 1 2 3 3 3 0 Fez1 GyrB_insert PF18053.1 EGR29835.1 - 2.6 7.9 14.0 0.082 12.8 3.9 2.7 2 0 0 2 2 2 0 DNA gyrase B subunit insert domain FAD-oxidase_C PF02913.19 EGR29836.1 - 7.4e-40 137.1 0.0 9.6e-40 136.8 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGR29836.1 - 1.3e-36 125.4 0.2 3.4e-36 124.0 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain DUF2624 PF11116.8 EGR29836.1 - 0.13 13.2 1.6 6.5 7.7 0.0 3.8 4 1 0 4 4 4 0 Protein of unknown function (DUF2624) Porin_3 PF01459.22 EGR29837.1 - 3.4e-16 59.5 1.7 4.9e-16 59.0 1.7 1.3 1 0 0 1 1 1 1 Eukaryotic porin AhpC-TSA PF00578.21 EGR29838.1 - 4e-31 107.5 0.0 7.7e-31 106.6 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family 1-cysPrx_C PF10417.9 EGR29838.1 - 3.5e-12 45.9 0.1 6.8e-12 45.0 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 EGR29838.1 - 1.1e-11 44.7 0.0 3.1e-11 43.2 0.0 1.7 2 0 0 2 2 2 1 Redoxin WD40 PF00400.32 EGR29839.1 - 2e-76 249.9 39.2 7.1e-06 26.7 0.1 14.7 15 0 0 15 15 15 13 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR29839.1 - 5.9e-17 61.7 9.0 0.31 11.3 0.0 9.8 2 2 7 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGR29839.1 - 3.2e-07 30.0 17.9 0.00049 19.5 4.1 3.8 1 1 2 3 3 3 3 WD40-like domain Nup160 PF11715.8 EGR29839.1 - 8.5e-07 28.0 25.5 0.39 9.3 0.1 9.5 7 2 4 11 11 11 5 Nucleoporin Nup120/160 YmzC PF14157.6 EGR29839.1 - 0.042 13.9 0.2 2.7 8.1 0.1 4.0 5 0 0 5 5 5 0 YmzC-like protein DUF98 PF01947.16 EGR29839.1 - 0.049 13.6 0.0 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 p-hydroxybenzoic acid synthase zf-B_box PF00643.24 EGR29839.1 - 3.2 8.0 11.5 0.21 11.7 5.7 2.1 2 0 0 2 2 2 0 B-box zinc finger N6-adenineMlase PF10237.9 EGR29840.1 - 5.3e-37 127.1 7.2 6.1e-37 126.9 7.2 1.0 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 EGR29840.1 - 0.026 14.1 0.1 0.037 13.7 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 EC042_2821 PF18740.1 EGR29840.1 - 1.4 8.7 10.0 0.21 11.4 6.3 1.5 2 0 0 2 2 2 0 EC042_2821-lke REase GTP_EFTU PF00009.27 EGR29841.1 - 4.9e-50 169.8 0.0 7.3e-50 169.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EGR29841.1 - 8.8e-36 122.3 2.6 1.7e-35 121.4 2.6 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EGR29841.1 - 1.3e-09 38.0 0.1 3.2e-09 36.7 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus Ras PF00071.22 EGR29841.1 - 2.2e-06 27.4 0.0 5e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EGR29841.1 - 5.1e-06 26.5 0.1 1.1e-05 25.5 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RF3_C PF16658.5 EGR29841.1 - 0.00011 22.1 0.0 0.00021 21.1 0.0 1.4 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain SRPRB PF09439.10 EGR29841.1 - 0.0039 16.7 0.0 0.0089 15.5 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit EFG_II PF14492.6 EGR29841.1 - 0.058 13.5 0.0 0.31 11.2 0.0 2.1 1 1 0 1 1 1 0 Elongation Factor G, domain II Roc PF08477.13 EGR29841.1 - 0.094 12.9 0.0 0.3 11.3 0.0 1.9 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EGR29843.1 - 1.4e-55 187.9 1.0 5.4e-55 186.0 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGR29843.1 - 1.1e-13 51.0 0.1 1.5e-12 47.4 0.0 2.7 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGR29843.1 - 1.3e-06 28.7 0.0 4.7e-06 26.9 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EGR29843.1 - 0.0014 18.7 0.0 0.0042 17.1 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EGR29843.1 - 0.0023 18.0 0.5 0.029 14.5 0.4 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase EFG_IV PF03764.18 EGR29843.1 - 0.073 12.9 0.0 0.073 12.9 0.0 3.4 4 0 0 4 4 4 0 Elongation factor G, domain IV eIF3_subunit PF08597.10 EGR29844.1 - 1.7e-17 64.1 20.3 2e-17 64.0 20.3 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Apc13p PF05839.11 EGR29844.1 - 0.093 12.9 3.5 0.2 11.8 2.9 1.9 2 0 0 2 2 2 0 Apc13p protein T2SSC PF11356.8 EGR29844.1 - 0.44 10.4 8.8 11 5.9 5.9 2.3 1 1 1 2 2 2 0 Type II secretion system protein C DNA_primase_S PF01896.19 EGR29845.1 - 0.11 12.5 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 DNA primase small subunit Pkinase PF00069.25 EGR29846.1 - 2.2e-69 233.7 0.5 3.7e-69 233.0 0.5 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29846.1 - 3.7e-51 173.9 0.0 5.3e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29846.1 - 1.6e-07 30.9 3.6 3e-05 23.5 0.0 2.9 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 EGR29846.1 - 0.00024 20.0 0.0 0.00046 19.1 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase RyR PF02026.16 EGR29846.1 - 0.11 12.7 4.0 0.21 11.8 0.4 2.6 2 0 0 2 2 2 0 RyR domain RRM_1 PF00076.22 EGR29847.1 - 1.4e-13 50.5 4.8 2.5e-08 33.6 1.5 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGR29847.1 - 0.0061 16.5 0.2 0.36 10.8 0.0 2.6 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif BAH PF01426.18 EGR29847.1 - 0.4 10.5 7.3 0.26 11.2 0.9 2.7 2 1 0 2 2 2 0 BAH domain RRM_1 PF00076.22 EGR29848.1 - 8.2e-14 51.2 0.2 3.6e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGR29848.1 - 0.0021 17.6 0.0 0.0035 16.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SpuA_C PF18033.1 EGR29848.1 - 0.0062 16.6 0.1 0.011 15.7 0.1 1.4 1 0 0 1 1 1 1 SpuA C-terminal RRM_occluded PF16842.5 EGR29848.1 - 0.067 13.1 0.1 0.12 12.2 0.1 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif ETC_C1_NDUFA5 PF04716.14 EGR29849.1 - 1.6e-14 53.4 0.3 3.4e-14 52.4 0.3 1.6 1 0 0 1 1 1 1 ETC complex I subunit conserved region Stap_Strp_tox_C PF02876.17 EGR29849.1 - 0.0015 18.8 0.8 0.0024 18.1 0.8 1.4 1 0 0 1 1 1 1 Staphylococcal/Streptococcal toxin, beta-grasp domain Zip PF02535.22 EGR29850.1 - 0.0069 15.6 4.3 0.06 12.6 0.0 2.9 2 0 0 2 2 2 1 ZIP Zinc transporter PAS_9 PF13426.7 EGR29850.1 - 0.0078 16.5 0.1 0.0078 16.5 0.1 4.2 3 0 0 3 3 3 1 PAS domain Imm58 PF15581.6 EGR29850.1 - 0.63 10.2 6.2 4.6 7.4 0.4 2.8 2 0 0 2 2 2 0 Immunity protein 58 PAS_9 PF13426.7 EGR29851.1 - 6.1e-05 23.2 0.4 0.0017 18.5 0.0 3.5 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EGR29851.1 - 0.0063 16.5 0.3 0.021 14.8 0.0 2.0 2 0 0 2 2 2 1 PAS fold BNIP2 PF12496.8 EGR29851.1 - 1.3 9.5 5.3 0.94 9.9 0.3 2.7 3 0 0 3 3 3 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Pkinase PF00069.25 EGR29853.1 - 2.8e-36 125.2 0.0 3.6e-36 124.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29853.1 - 4.6e-21 75.3 0.0 5.8e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29853.1 - 1.9e-05 24.1 0.1 7.1e-05 22.3 0.1 1.8 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGR29853.1 - 0.00022 21.2 0.0 0.00033 20.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGR29853.1 - 0.0081 15.0 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Myotub-related PF06602.14 EGR29856.1 - 7.1e-112 373.8 8.0 7.1e-112 373.8 8.0 1.9 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EGR29856.1 - 0.0054 16.7 0.4 0.028 14.4 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 EGR29856.1 - 0.011 15.5 0.1 0.011 15.5 0.1 2.7 2 1 0 2 2 2 0 Dual specificity phosphatase, catalytic domain Med2 PF11214.8 EGR29856.1 - 0.18 11.9 14.4 0.68 10.1 14.4 2.0 1 0 0 1 1 1 0 Mediator complex subunit 2 PCRF PF03462.18 EGR29856.1 - 3.5 7.4 7.5 8.9 6.1 7.5 1.6 1 0 0 1 1 1 0 PCRF domain GAS PF13851.6 EGR29857.1 - 2.1e-10 40.3 124.7 0.031 13.6 10.4 8.1 1 1 7 8 8 8 6 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 EGR29857.1 - 4.4e-09 35.9 128.8 0.0044 16.2 22.4 6.8 1 1 5 6 6 6 4 Vacuolar sorting 38 and autophagy-related subunit 14 HOOK PF05622.12 EGR29857.1 - 6.9e-07 27.8 111.0 0.00069 17.9 63.4 3.3 1 1 2 3 3 3 3 HOOK protein AAA_13 PF13166.6 EGR29857.1 - 1.4e-06 27.3 114.6 0.001 17.8 25.4 5.1 1 1 4 5 5 5 4 AAA domain DHR10 PF18595.1 EGR29857.1 - 7.1e-06 26.1 133.6 0.00078 19.5 9.5 9.0 1 1 5 8 8 8 4 Designed helical repeat protein 10 domain ATG16 PF08614.11 EGR29857.1 - 9.3e-06 26.0 111.8 0.075 13.2 2.7 8.7 1 1 5 7 7 7 4 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 EGR29857.1 - 0.00013 21.8 140.7 0.033 14.0 15.7 8.6 3 3 6 9 9 9 3 Coiled-coil region of CCDC155 or KASH BLOC1_2 PF10046.9 EGR29857.1 - 0.00023 21.4 119.5 0.17 12.2 3.2 11.2 1 1 9 11 11 11 5 Biogenesis of lysosome-related organelles complex-1 subunit 2 Filament PF00038.21 EGR29857.1 - 0.0062 16.2 131.5 2.9 7.4 46.5 8.6 1 1 3 4 4 4 2 Intermediate filament protein Pox_A_type_inc PF04508.12 EGR29857.1 - 0.035 14.0 49.4 2.1 8.3 0.2 12.8 10 2 2 12 12 12 0 Viral A-type inclusion protein repeat HMMR_N PF15905.5 EGR29857.1 - 0.1 12.0 139.5 0.11 12.0 15.0 6.6 1 1 6 7 7 7 0 Hyaluronan mediated motility receptor N-terminal Herpes_ICP4_N PF03584.15 EGR29857.1 - 0.19 11.5 21.1 1.3 8.8 0.1 5.9 7 1 1 8 8 8 0 Herpesvirus ICP4-like protein N-terminal region Phage_HK97_TLTM PF06120.11 EGR29857.1 - 0.69 9.0 101.7 0.044 13.0 3.7 8.1 1 1 7 8 8 8 0 Tail length tape measure protein Clp_N PF02861.20 EGR29857.1 - 0.76 9.9 3.4 1.6e+02 2.5 0.1 4.1 3 0 0 3 3 3 0 Clp amino terminal domain, pathogenicity island component TMF_TATA_bd PF12325.8 EGR29857.1 - 0.94 9.7 138.5 0.87 9.8 1.0 12.3 1 1 12 13 13 13 0 TATA element modulatory factor 1 TATA binding MAD PF05557.13 EGR29857.1 - 2.3 6.5 145.5 0.51 8.6 20.7 6.0 1 1 6 7 7 7 0 Mitotic checkpoint protein CENP-F_leu_zip PF10473.9 EGR29857.1 - 3.8 7.6 128.9 2.8 8.0 7.2 9.0 1 1 6 8 8 8 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Cast PF10174.9 EGR29857.1 - 3.8 5.6 111.3 0.28 9.3 35.4 3.2 1 1 2 3 3 3 0 RIM-binding protein of the cytomatrix active zone Spc7 PF08317.11 EGR29857.1 - 3.9 6.3 130.1 0.54 9.1 13.7 8.2 1 1 7 8 8 8 0 Spc7 kinetochore protein Cytochrom_B562 PF07361.11 EGR29857.1 - 6.1 7.6 46.2 1.4 9.6 0.5 8.3 1 1 9 10 10 10 0 Cytochrome b562 AvrLm4-7 PF18661.1 EGR29857.1 - 7.5 7.6 17.0 31 5.7 0.5 5.2 3 3 0 3 3 3 0 Avirulence Effector AvrLm4-7 DUF4200 PF13863.6 EGR29858.1 - 9.7e-26 90.5 32.2 9.7e-26 90.5 32.2 3.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4200) DUF948 PF06103.11 EGR29858.1 - 3.7 7.9 8.8 2.3 8.5 4.3 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Kelch_6 PF13964.6 EGR29859.1 - 1.7e-25 88.4 13.0 3.8e-06 27.0 0.1 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGR29859.1 - 4e-21 74.8 7.2 8.6e-07 28.9 0.2 5.6 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_2 PF07646.15 EGR29859.1 - 1.4e-19 69.2 14.6 3.4e-06 26.8 0.1 6.8 7 0 0 7 7 7 6 Kelch motif Kelch_1 PF01344.25 EGR29859.1 - 1.5e-18 66.1 9.1 1.2e-05 24.8 0.1 6.9 6 1 0 6 6 6 4 Kelch motif Kelch_5 PF13854.6 EGR29859.1 - 1.6e-13 50.3 11.9 0.02 14.8 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 EGR29859.1 - 2.8e-08 33.9 2.7 0.085 13.2 0.0 6.3 7 0 0 7 7 7 2 Galactose oxidase, central domain bZIP_Maf PF03131.17 EGR29859.1 - 2.7 8.6 6.3 0.32 11.5 1.4 2.0 3 0 0 3 3 3 0 bZIP Maf transcription factor CARM1 PF11531.8 EGR29860.1 - 1.5 9.0 6.7 0.42 10.8 3.7 1.6 2 0 0 2 2 2 0 Coactivator-associated arginine methyltransferase 1 N terminal Suv3_N PF18114.1 EGR29861.1 - 0.0038 17.3 3.6 0.0056 16.8 3.6 1.2 1 0 0 1 1 1 1 Suv3 helical N-terminal domain WD40 PF00400.32 EGR29862.1 - 9.8e-14 51.5 0.1 0.00079 20.2 0.0 6.6 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR29862.1 - 6.1e-05 23.2 0.0 4.2 7.7 0.0 5.7 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain CLPTM1 PF05602.12 EGR29863.1 - 1.2e-78 265.1 24.3 1.2e-78 265.1 24.3 2.1 1 1 1 2 2 2 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) DUF960 PF06124.11 EGR29863.1 - 0.015 15.9 0.1 0.015 15.9 0.1 4.2 4 0 0 4 4 4 0 Staphylococcal protein of unknown function (DUF960) PQ-loop PF04193.14 EGR29863.1 - 0.016 14.9 0.2 0.016 14.9 0.2 2.4 2 0 0 2 2 2 0 PQ loop repeat Pyr_redox_2 PF07992.14 EGR29865.1 - 6.7e-20 71.5 0.0 1.7e-19 70.2 0.0 1.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGR29865.1 - 0.0067 15.6 0.0 1 8.5 0.0 2.1 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGR29865.1 - 0.038 14.0 0.0 2.1 8.3 0.0 2.9 4 0 0 4 4 4 0 FAD-NAD(P)-binding KH_1 PF00013.29 EGR29865.1 - 0.042 13.7 0.3 0.12 12.3 0.3 1.7 1 0 0 1 1 1 0 KH domain HTH_40 PF14493.6 EGR29866.1 - 1.3 9.5 8.9 7.2 7.2 0.3 3.6 2 1 1 3 3 3 0 Helix-turn-helix domain NUDIX PF00293.28 EGR29868.1 - 7.2e-13 48.7 0.0 8.5e-13 48.5 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain DUF1917 PF08939.10 EGR29868.1 - 0.033 14.1 0.2 0.053 13.4 0.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF1917) DSPc PF00782.20 EGR29869.1 - 3.4e-09 36.6 0.1 6.3e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTEN_C2 PF10409.9 EGR29869.1 - 6.1e-09 35.7 0.9 1.6e-08 34.4 0.7 1.8 2 0 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein Y_phosphatase PF00102.27 EGR29869.1 - 2.3e-06 27.4 0.2 4.3e-06 26.5 0.0 1.5 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EGR29869.1 - 0.00081 19.4 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family CDKN3 PF05706.12 EGR29869.1 - 0.0022 17.7 0.0 0.0032 17.1 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 EGR29869.1 - 0.0031 17.7 0.5 0.0066 16.6 0.5 1.7 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 EGR29869.1 - 0.034 13.7 0.8 0.034 13.7 0.8 1.7 2 1 0 2 2 2 0 Tyrosine phosphatase family HlyIII PF03006.20 EGR29870.1 - 5.5e-54 183.2 6.0 8.6e-54 182.6 6.0 1.3 1 1 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 EGR29870.1 - 0.0011 19.0 5.1 0.028 14.5 5.1 3.0 1 1 0 1 1 1 1 Protein of unknown function (DUF962) HHH_4 PF14490.6 EGR29870.1 - 0.0064 16.5 8.0 0.24 11.4 0.7 2.6 3 0 0 3 3 3 2 Helix-hairpin-helix containing domain ATP-synt_8 PF00895.20 EGR29870.1 - 0.15 12.5 7.1 4.4 7.8 1.5 3.2 2 0 0 2 2 2 0 ATP synthase protein 8 DLP_helical PF18709.1 EGR29870.1 - 2 7.5 7.7 3.1 6.9 1.0 2.4 2 1 1 3 3 3 0 Dynamin-like helical domain DUF2070 PF09843.9 EGR29870.1 - 4.2 5.5 11.9 9.4 4.4 11.9 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) VWA_2 PF13519.6 EGR29871.1 - 4.9e-11 43.2 1.7 2e-10 41.3 0.1 2.7 2 1 1 3 3 3 1 von Willebrand factor type A domain HEM4 PF02602.15 EGR29871.1 - 0.0093 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD Y2_Tnp PF04986.13 EGR29871.1 - 0.032 14.3 4.7 1.7 8.7 0.2 3.0 3 0 0 3 3 3 0 Putative transposase UIM PF02809.20 EGR29871.1 - 0.077 13.0 9.6 0.17 11.9 0.4 3.0 3 0 0 3 3 3 0 Ubiquitin interaction motif UNC-79 PF14776.6 EGR29871.1 - 6 5.5 8.6 0.12 11.1 1.3 1.7 2 0 0 2 2 2 0 Cation-channel complex subunit UNC-79 ResIII PF04851.15 EGR29872.1 - 6.4e-25 88.1 0.2 6.4e-25 88.1 0.2 3.5 3 2 0 3 3 3 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGR29872.1 - 2.8e-20 72.7 0.8 2.8e-20 72.7 0.8 3.5 5 0 0 5 5 5 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGR29872.1 - 9.6e-19 67.8 0.2 5.1e-18 65.5 0.0 2.4 2 1 0 2 2 2 1 DEAD/DEAH box helicase Transketolase_C PF02780.20 EGR29873.1 - 6.3e-41 139.1 0.0 1.3e-40 138.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 EGR29873.1 - 5.5e-37 127.1 0.0 3.8e-36 124.4 0.0 2.1 1 1 0 1 1 1 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 EGR29873.1 - 0.0059 16.9 0.0 0.012 15.9 0.0 1.5 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II PI-PLC-X PF00388.19 EGR29874.1 - 7.8e-10 38.5 0.1 2.3e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-specific phospholipase C, X domain ZNRF_3_ecto PF18212.1 EGR29874.1 - 0.0073 16.3 0.0 0.013 15.5 0.0 1.3 1 0 0 1 1 1 1 ZNRF-3 Ectodomain TMF_DNA_bd PF12329.8 EGR29875.1 - 0.0047 16.9 5.2 0.019 15.0 5.2 1.8 1 1 0 1 1 1 1 TATA element modulatory factor 1 DNA binding TUDOR PF00567.24 EGR29875.1 - 0.078 13.0 0.0 0.094 12.7 0.0 1.0 1 0 0 1 1 1 0 Tudor domain Kinesin PF00225.23 EGR29876.1 - 1.9e-113 378.8 4.0 1.9e-113 378.8 4.0 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGR29876.1 - 2.7e-25 89.1 1.1 2.7e-25 89.1 1.1 2.2 2 0 0 2 2 2 1 Microtubule binding SKN1 PF03935.15 EGR29876.1 - 0.022 13.2 1.2 0.034 12.6 1.2 1.2 1 0 0 1 1 1 0 Beta-glucan synthesis-associated protein (SKN1) Roc PF08477.13 EGR29876.1 - 0.025 14.8 0.2 4.2 7.6 0.1 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_7 PF12775.7 EGR29876.1 - 0.029 13.9 0.2 0.029 13.9 0.2 3.3 3 1 0 3 3 3 0 P-loop containing dynein motor region Glyco_hydro_18 PF00704.28 EGR29877.1 - 4e-13 49.8 2.6 3e-11 43.6 1.4 2.0 1 1 1 2 2 2 2 Glycosyl hydrolases family 18 DUF4945 PF16303.5 EGR29877.1 - 0.11 12.4 0.1 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4945) Anemone_cytotox PF06369.12 EGR29877.1 - 0.28 10.8 1.3 0.91 9.1 0.4 2.0 1 1 1 2 2 2 0 Sea anemone cytotoxic protein Peptidase_G2 PF11962.8 EGR29878.1 - 0.64 9.4 0.0 0.64 9.4 0.0 2.7 3 0 0 3 3 3 0 Peptidase_G2, IMC autoproteolytic cleavage domain Ras PF00071.22 EGR29879.1 - 2.9e-57 192.8 1.0 4.1e-57 192.3 1.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR29879.1 - 1.8e-34 118.5 0.6 1.8e-34 118.5 0.6 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR29879.1 - 1.7e-16 60.2 1.0 2.6e-16 59.6 1.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGR29879.1 - 1.3e-06 27.9 2.0 1.5e-06 27.7 1.1 1.6 1 1 1 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGR29879.1 - 3.6e-06 26.7 0.5 1.1e-05 25.1 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGR29879.1 - 3.4e-05 23.9 0.2 7.6e-05 22.8 0.1 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGR29879.1 - 0.00011 21.7 0.2 0.00018 21.0 0.2 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 EGR29879.1 - 0.0069 15.8 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein AAA PF00004.29 EGR29879.1 - 0.044 14.2 0.2 0.38 11.2 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Hydrolase_4 PF12146.8 EGR29880.1 - 1.1e-12 47.8 0.0 1.2e-08 34.5 0.0 3.0 3 0 0 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR29880.1 - 4.3e-08 33.1 0.0 1.1e-06 28.6 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold PhoPQ_related PF10142.9 EGR29880.1 - 0.00034 19.4 0.5 0.00051 18.8 0.5 1.2 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein DUF1749 PF08538.10 EGR29880.1 - 0.00048 19.3 0.0 0.001 18.2 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1749) Peptidase_S15 PF02129.18 EGR29880.1 - 0.00084 19.0 0.0 0.13 11.8 0.0 2.7 2 1 1 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) DUF915 PF06028.11 EGR29880.1 - 0.0083 15.5 0.1 0.0083 15.5 0.1 2.1 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) FSH1 PF03959.13 EGR29880.1 - 0.0086 15.8 0.1 0.039 13.6 0.0 2.1 2 1 0 2 2 2 1 Serine hydrolase (FSH1) L_lactis_ph-MCP PF06673.11 EGR29881.1 - 0.085 11.8 1.5 0.093 11.7 1.5 1.0 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein FadA PF09403.10 EGR29881.1 - 0.091 13.3 16.8 0.058 13.9 13.3 2.2 1 1 1 2 2 2 0 Adhesion protein FadA DUF724 PF05266.14 EGR29881.1 - 0.12 12.2 8.1 0.19 11.5 8.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Spc29 PF17082.5 EGR29881.1 - 0.15 11.9 6.0 0.19 11.6 5.5 1.4 1 1 1 2 2 2 0 Spindle Pole Component 29 Anti-adapt_IraP PF10796.9 EGR29881.1 - 0.57 10.8 7.0 3.4 8.3 1.1 2.5 1 1 1 2 2 2 0 Sigma-S stabilisation anti-adaptor protein DUF1664 PF07889.12 EGR29881.1 - 0.6 10.1 5.9 1.4 9.0 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) BLOC1_2 PF10046.9 EGR29881.1 - 0.63 10.4 14.7 0.69 10.3 2.6 2.7 2 1 1 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CENP-F_leu_zip PF10473.9 EGR29881.1 - 0.95 9.5 11.8 0.17 11.9 4.3 2.2 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ZapB PF06005.12 EGR29881.1 - 2.3 8.7 13.9 2.3 8.7 3.4 2.2 2 0 0 2 2 2 0 Cell division protein ZapB BRE1 PF08647.11 EGR29882.1 - 1.7e-13 50.5 22.3 1.7e-13 50.5 22.3 8.8 5 2 3 9 9 9 2 BRE1 E3 ubiquitin ligase ERM PF00769.19 EGR29882.1 - 0.0022 17.9 23.1 0.0022 17.9 23.1 5.4 1 1 4 5 5 5 2 Ezrin/radixin/moesin family MORN PF02493.20 EGR29883.1 - 3.9e-52 171.1 80.2 2.7e-08 33.2 1.3 11.2 12 0 0 12 12 12 10 MORN repeat DUF3048_C PF17479.2 EGR29883.1 - 2 8.9 30.6 18 5.8 5.5 6.0 1 1 4 6 6 6 0 Protein of unknown function (DUF3048) C-terminal domain TTL PF03133.15 EGR29884.1 - 5.3e-62 209.6 27.3 5.8e-62 209.5 15.9 2.1 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR29884.1 - 6.6e-09 35.4 5.0 2.7e-06 26.8 0.1 3.4 3 1 0 3 3 3 2 YheC/D like ATP-grasp Ank_2 PF12796.7 EGR29884.1 - 0.00017 22.1 0.1 0.0012 19.3 0.0 2.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) ATPgrasp_ST PF14397.6 EGR29884.1 - 0.00051 19.4 0.3 0.018 14.3 0.0 2.3 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Ank_5 PF13857.6 EGR29884.1 - 0.0025 18.1 0.0 0.0055 17.0 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR29884.1 - 0.014 15.9 0.0 0.074 13.6 0.0 2.4 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.6 EGR29884.1 - 0.017 15.7 0.0 0.074 13.7 0.0 2.2 1 1 1 2 2 2 0 Ankyrin repeats (many copies) RhoGAP-FF1 PF16512.5 EGR29884.1 - 3.3 8.5 9.7 0.37 11.5 0.5 3.4 3 0 0 3 3 3 0 p190-A and -B Rho GAPs FF domain Ras PF00071.22 EGR29885.1 - 2.6e-56 189.7 0.2 3.1e-56 189.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR29885.1 - 6.7e-37 126.4 0.2 1.5e-36 125.3 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR29885.1 - 5.1e-17 61.9 0.2 6.9e-17 61.4 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGR29885.1 - 1.5e-07 31.2 0.1 6.1e-06 25.9 0.1 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGR29885.1 - 1.2e-06 28.5 0.0 2.3e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGR29885.1 - 1.2e-05 24.8 0.3 1.6e-05 24.4 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 EGR29885.1 - 0.00015 21.6 0.1 0.00019 21.3 0.1 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EGR29885.1 - 0.00019 21.3 0.1 0.004 17.1 0.1 2.1 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EGR29885.1 - 0.0018 17.7 0.1 0.004 16.6 0.1 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 EGR29885.1 - 0.0097 15.3 0.1 0.039 13.4 0.0 2.0 3 0 0 3 3 3 1 Bacterial TniB protein UPF0542 PF15086.6 EGR29885.1 - 0.017 15.0 1.8 0.02 14.8 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 AAA_7 PF12775.7 EGR29885.1 - 0.02 14.4 0.1 0.05 13.1 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region MMR_HSR1_Xtn PF16897.5 EGR29885.1 - 0.037 14.0 0.2 0.055 13.5 0.2 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain CHASE2 PF05226.11 EGR29885.1 - 0.098 12.4 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 CHASE2 domain CoA_trans PF01144.23 EGR29886.1 - 2e-108 360.8 5.5 2.8e-73 245.9 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 EGR29886.1 - 0.045 12.1 0.0 0.067 11.5 0.0 1.3 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter Aldo_ket_red PF00248.21 EGR29887.1 - 1.9e-18 66.7 0.4 9.3e-15 54.6 0.0 2.9 2 1 0 2 2 2 2 Aldo/keto reductase family LRR_6 PF13516.6 EGR29888.1 - 1.5e-05 24.7 10.1 0.023 14.7 0.0 4.8 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 EGR29888.1 - 0.0057 17.0 6.9 1.6 9.5 0.1 4.8 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_4 PF12799.7 EGR29888.1 - 2.8 8.5 16.3 0.17 12.4 2.0 3.1 3 1 0 3 3 3 0 Leucine Rich repeats (2 copies) AAA_6 PF12774.7 EGR29890.1 - 4.2e-154 512.4 7.5 2.7e-153 509.7 0.0 3.8 4 0 0 4 4 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGR29890.1 - 4.9e-131 437.5 25.4 4.9e-131 437.5 25.4 6.6 6 1 0 7 7 5 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 EGR29890.1 - 3.9e-109 364.6 0.8 3.2e-108 361.6 0.0 3.0 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EGR29890.1 - 5e-94 314.4 1.1 5e-94 314.4 1.1 3.4 4 0 0 4 4 3 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 EGR29890.1 - 5.6e-80 267.1 0.2 5.5e-73 244.3 0.0 3.9 3 0 0 3 3 3 3 P-loop containing dynein motor region AAA_9 PF12781.7 EGR29890.1 - 3.3e-77 258.5 4.3 3.3e-77 258.5 4.3 5.8 9 0 0 9 9 7 1 ATP-binding dynein motor region AAA_lid_11 PF18198.1 EGR29890.1 - 3.9e-58 195.9 5.0 1.8e-57 193.7 0.1 3.4 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGR29890.1 - 3.8e-53 178.6 0.5 3.5e-47 159.4 0.1 4.9 5 0 0 5 5 3 2 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EGR29890.1 - 2.5e-32 111.7 5.9 1.2e-31 109.5 1.7 4.0 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 EGR29890.1 - 6.1e-28 97.8 14.0 1.6e-27 96.5 14.0 1.8 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 EGR29890.1 - 2.2e-22 79.6 0.0 8.2e-08 32.3 0.0 5.7 5 1 0 5 5 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EGR29890.1 - 4e-17 62.3 1.6 1.8e-16 60.2 0.1 3.1 2 0 0 2 2 1 1 AAA+ lid domain AAA PF00004.29 EGR29890.1 - 4.3e-10 40.1 0.5 0.094 13.1 0.0 5.3 4 1 1 5 5 5 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGR29890.1 - 5.2e-08 33.3 2.9 1.7 8.9 0.0 6.6 6 0 0 6 6 5 3 AAA domain T2SSE PF00437.20 EGR29890.1 - 0.00026 20.1 3.0 0.7 8.9 0.1 4.2 5 0 0 5 5 5 2 Type II/IV secretion system protein AAA_18 PF13238.6 EGR29890.1 - 0.00038 21.0 1.1 3.6 8.1 0.0 4.8 5 0 0 5 5 2 2 AAA domain AAA_16 PF13191.6 EGR29890.1 - 0.0034 17.8 1.1 3.8 7.9 0.0 4.1 5 0 0 5 5 2 1 AAA ATPase domain Sigma54_activat PF00158.26 EGR29890.1 - 0.0039 16.9 0.4 1.4 8.6 0.1 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 EGR29890.1 - 0.0071 16.1 0.0 4.9 6.8 0.0 4.1 4 0 0 4 4 4 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGR29890.1 - 0.0091 15.4 0.5 0.45 9.9 0.1 3.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 EGR29890.1 - 0.025 14.3 0.2 11 5.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain RNA_helicase PF00910.22 EGR29890.1 - 0.029 14.8 11.6 4.5 7.7 0.0 6.0 6 0 0 6 6 4 0 RNA helicase AAA_lid_7 PF17867.1 EGR29890.1 - 0.074 13.3 0.0 0.29 11.4 0.0 2.1 1 0 0 1 1 1 0 Midasin AAA lid domain DUF853 PF05872.12 EGR29890.1 - 0.72 8.4 10.3 1.9 7.0 0.1 3.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) Sortilin-Vps10 PF15902.5 EGR29891.1 - 2.5e-87 293.5 9.9 4e-87 292.8 9.9 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EGR29891.1 - 5e-44 150.6 9.3 5e-44 150.6 9.3 1.9 2 0 0 2 2 2 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EGR29891.1 - 6.6e-08 31.4 9.1 0.58 10.4 0.1 6.3 6 0 0 6 6 6 3 BNR/Asp-box repeat BNR_6 PF15899.5 EGR29891.1 - 0.011 15.8 1.8 1.3 9.2 0.0 4.6 4 0 0 4 4 4 0 BNR-Asp box repeat CHB_HEX_C PF03174.13 EGR29891.1 - 0.015 15.2 0.2 0.11 12.5 0.2 2.4 2 0 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain preSET_CXC PF18264.1 EGR29891.1 - 0.59 10.6 3.7 1.5 9.4 3.7 1.7 1 0 0 1 1 1 0 CXC domain DUF3298 PF11738.8 EGR29891.1 - 5.6 8.1 6.9 12 7.0 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3298) SHIPPO-rpt PF07004.12 EGR29892.1 - 3.9e-14 52.8 35.0 0.15 13.0 0.3 10.2 9 0 0 9 9 9 8 Sperm-tail PG-rich repeat ECR1_N PF14382.6 EGR29892.1 - 0.0017 18.1 0.0 3.4 7.5 0.0 4.2 4 0 0 4 4 4 1 Exosome complex exonuclease RRP4 N-terminal region GATase PF00117.28 EGR29892.1 - 0.02 14.7 0.1 0.44 10.3 0.1 2.8 2 0 0 2 2 2 0 Glutamine amidotransferase class-I MucBP PF06458.12 EGR29892.1 - 8.5 7.5 7.8 15 6.6 3.1 3.6 2 1 0 2 2 2 0 MucBP domain Phage-tail_1 PF09097.10 EGR29893.1 - 0.026 14.3 0.1 0.051 13.4 0.1 1.5 1 0 0 1 1 1 0 Baseplate structural protein, domain 1 PAS_9 PF13426.7 EGR29894.1 - 0.0038 17.5 0.1 0.0038 17.5 0.1 4.1 4 0 0 4 4 4 1 PAS domain PAS PF00989.25 EGR29894.1 - 0.023 14.7 1.1 7.7 6.6 0.0 3.3 3 0 0 3 3 3 0 PAS fold Aconitase PF00330.20 EGR29895.1 - 1.1e-183 611.5 0.0 1.4e-183 611.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGR29895.1 - 9.3e-43 145.7 0.3 4.3e-42 143.5 0.0 2.3 2 0 0 2 2 2 1 Aconitase C-terminal domain AAA PF00004.29 EGR29896.1 - 1.7e-45 154.7 1.0 2.8e-43 147.5 0.0 2.5 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGR29896.1 - 3.8e-11 42.8 0.1 1.7e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EGR29896.1 - 8.1e-11 41.6 0.0 1.8e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGR29896.1 - 1.9e-08 34.4 0.2 7.1e-08 32.6 0.2 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGR29896.1 - 2.5e-07 30.9 0.0 8.5e-07 29.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EGR29896.1 - 4.6e-06 26.0 0.0 9.9e-06 24.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EGR29896.1 - 5.5e-06 26.9 0.1 0.00036 21.0 0.0 2.6 1 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EGR29896.1 - 9.7e-05 22.2 0.0 0.00045 20.0 0.0 2.1 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGR29896.1 - 0.00016 22.0 2.3 0.021 15.1 0.0 3.1 2 1 1 3 3 3 1 AAA domain AAA_18 PF13238.6 EGR29896.1 - 0.00018 22.0 0.0 0.00051 20.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EGR29896.1 - 0.001 19.4 0.0 0.0033 17.8 0.0 1.9 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 EGR29896.1 - 0.0015 18.3 0.0 0.0034 17.2 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGR29896.1 - 0.0021 17.5 0.3 0.0051 16.2 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 EGR29896.1 - 0.0024 17.6 0.2 0.0078 15.9 0.2 2.0 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGR29896.1 - 0.0026 18.0 0.0 0.0049 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EGR29896.1 - 0.0032 17.4 0.6 0.03 14.2 0.1 2.5 3 0 0 3 3 3 1 NTPase AAA_7 PF12775.7 EGR29896.1 - 0.0042 16.6 0.1 0.039 13.5 0.1 2.2 1 1 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EGR29896.1 - 0.0047 16.2 0.1 0.016 14.5 0.0 1.9 3 0 0 3 3 3 1 TIP49 P-loop domain AAA_24 PF13479.6 EGR29896.1 - 0.005 16.6 0.1 0.013 15.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EGR29896.1 - 0.0055 16.4 0.1 0.16 11.6 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 EGR29896.1 - 0.007 16.4 0.0 0.019 15.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGR29896.1 - 0.0075 16.4 0.1 0.027 14.6 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGR29896.1 - 0.01 15.4 1.2 0.037 13.6 0.2 2.1 1 1 1 2 2 2 0 AAA domain AAA_3 PF07726.11 EGR29896.1 - 0.013 15.4 0.1 0.049 13.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 EGR29896.1 - 0.021 13.9 0.0 0.04 13.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 EGR29896.1 - 0.03 13.7 1.3 0.15 11.4 0.0 2.5 3 0 0 3 3 3 0 KaiC TsaE PF02367.17 EGR29896.1 - 0.034 14.1 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 EGR29896.1 - 0.039 13.4 0.0 2.1 7.7 0.0 2.7 3 0 0 3 3 3 0 Bacterial TniB protein Viral_Hsp90 PF03225.14 EGR29896.1 - 0.052 12.0 0.1 0.078 11.5 0.1 1.2 1 0 0 1 1 1 0 Viral heat shock protein Hsp90 homologue AAA_11 PF13086.6 EGR29896.1 - 0.096 12.5 0.2 0.18 11.6 0.0 1.8 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 EGR29896.1 - 0.12 12.3 0.1 0.38 10.7 0.1 1.9 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.6 EGR29896.1 - 0.13 12.6 0.3 0.45 10.8 0.1 1.9 2 0 0 2 2 1 0 AAA domain Sigma54_activ_2 PF14532.6 EGR29896.1 - 0.16 12.1 0.1 1.3 9.2 0.0 2.6 2 1 1 3 3 2 0 Sigma-54 interaction domain Thymidylate_kin PF02223.17 EGR29897.1 - 2e-21 76.5 0.0 2.3e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase TGT PF01702.18 EGR29898.1 - 1.1e-134 449.0 0.2 1.4e-134 448.7 0.2 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Pkinase PF00069.25 EGR29899.1 - 2e-43 148.7 1.4 2.5e-43 148.3 1.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29899.1 - 2.4e-28 99.1 0.2 3.1e-28 98.8 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29899.1 - 7.1e-06 25.5 0.7 1.3e-05 24.7 0.0 1.8 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 EGR29899.1 - 3e-05 23.0 1.1 0.0045 15.8 0.1 2.1 1 1 1 2 2 2 2 Fungal protein kinase FTA2 PF13095.6 EGR29899.1 - 0.012 15.2 3.8 0.03 13.9 0.7 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EGR29899.1 - 0.018 14.0 8.2 0.035 13.1 8.2 1.5 1 1 0 1 1 1 0 Haspin like kinase domain WD40 PF00400.32 EGR29900.1 - 1.8e-11 44.4 3.8 0.00016 22.4 0.2 3.7 3 1 0 3 3 3 2 WD domain, G-beta repeat WD40_like PF17005.5 EGR29900.1 - 0.00027 20.4 4.4 0.0013 18.2 4.4 1.8 1 1 0 1 1 1 1 WD40-like domain DKNYY PF13644.6 EGR29900.1 - 0.033 15.0 0.2 0.045 14.5 0.2 1.3 1 0 0 1 1 1 0 DKNYY family Izumo-Ig PF16706.5 EGR29900.1 - 0.15 12.1 0.0 0.74 9.9 0.0 2.0 2 0 0 2 2 2 0 Izumo-like Immunoglobulin domain WD40 PF00400.32 EGR29901.1 - 1.9e-08 34.8 0.9 9.9e-08 32.5 0.4 2.2 2 0 0 2 2 2 1 WD domain, G-beta repeat NTNH_C PF08470.10 EGR29901.1 - 0.038 13.9 0.1 0.044 13.7 0.1 1.2 1 0 0 1 1 1 0 Nontoxic nonhaemagglutinin C-terminal PK PF00224.21 EGR29902.1 - 8.7e-63 212.3 6.7 7.2e-46 156.7 0.7 2.5 2 1 0 2 2 2 2 Pyruvate kinase, barrel domain PK_C PF02887.16 EGR29902.1 - 4.2e-24 85.0 0.1 1.5e-23 83.2 0.1 2.1 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain Hydrolase_4 PF12146.8 EGR29902.1 - 7.5e-09 35.2 0.0 6.2e-06 25.6 0.0 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR29902.1 - 2.9e-08 33.7 0.1 0.0024 17.6 0.0 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 EGR29902.1 - 4e-08 32.3 0.8 9.2e-06 24.6 0.8 3.2 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Peptidase_S9 PF00326.21 EGR29902.1 - 1.2e-06 28.2 0.0 2.6e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF1057 PF06342.12 EGR29902.1 - 4.9e-05 22.5 0.1 0.00019 20.6 0.1 2.0 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Abhydrolase_2 PF02230.16 EGR29902.1 - 0.0026 17.6 0.3 0.03 14.1 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DLH PF01738.18 EGR29902.1 - 0.0029 17.2 0.0 0.036 13.6 0.0 2.5 2 1 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.11 EGR29902.1 - 0.017 15.0 1.2 8 6.3 0.0 3.4 2 2 2 4 4 4 0 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 EGR29902.1 - 0.031 14.0 1.0 1.4 8.6 0.0 2.6 2 0 0 2 2 2 0 Serine hydrolase (FSH1) HpcH_HpaI PF03328.14 EGR29902.1 - 0.042 13.0 0.4 0.12 11.5 0.2 1.7 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family Lipase_3 PF01764.25 EGR29902.1 - 0.056 13.3 0.0 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 Lipase (class 3) SurA_N_3 PF13624.6 EGR29904.1 - 1.6 8.5 4.5 3.1 7.6 1.3 2.1 2 0 0 2 2 2 0 SurA N-terminal domain EF-hand_7 PF13499.6 EGR29905.1 - 7e-24 84.1 14.0 4.7e-12 46.2 0.5 4.5 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 EGR29905.1 - 1.2e-23 80.8 7.0 2.7e-06 26.5 0.1 6.9 7 0 0 7 7 7 4 EF hand EF-hand_6 PF13405.6 EGR29905.1 - 5e-21 72.8 9.5 6.4e-07 28.8 0.2 7.0 7 0 0 7 7 7 4 EF-hand domain EF-hand_5 PF13202.6 EGR29905.1 - 2.7e-15 55.1 5.5 3.3e-05 23.2 0.0 6.3 7 0 0 7 7 7 3 EF hand EF-hand_8 PF13833.6 EGR29905.1 - 1.2e-14 53.8 9.6 0.0003 20.6 0.2 5.4 4 1 1 5 5 5 4 EF-hand domain pair DUF5580 PF17743.1 EGR29905.1 - 1.2e-05 24.1 4.1 0.00081 18.0 0.6 2.1 2 0 0 2 2 2 2 Family of unknown function (DUF5580) Caleosin PF05042.13 EGR29905.1 - 0.0033 17.4 0.7 4.5 7.2 0.0 3.9 2 2 1 4 4 4 1 Caleosin related protein DUF4898 PF16239.5 EGR29905.1 - 0.0052 16.7 0.1 0.017 15.1 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4898) NleF_casp_inhib PF16809.5 EGR29905.1 - 0.028 14.4 0.1 0.062 13.2 0.1 1.6 1 0 0 1 1 1 0 NleF caspase inhibitor EF-hand_10 PF14788.6 EGR29905.1 - 0.032 14.1 0.2 0.032 14.1 0.2 4.6 4 1 1 5 5 5 0 EF hand MetOD2 PF18548.1 EGR29905.1 - 0.04 14.0 0.9 0.22 11.7 0.1 2.5 2 0 0 2 2 2 0 Metanogen output domain 2 ParB PF08775.10 EGR29905.1 - 0.049 14.1 2.5 0.066 13.7 0.6 2.1 2 1 0 2 2 2 0 ParB family SPARC_Ca_bdg PF10591.9 EGR29905.1 - 0.087 13.2 3.9 1 9.7 0.2 3.2 1 1 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region PaaX PF07848.12 EGR29905.1 - 0.14 12.4 0.0 1 9.6 0.0 2.5 3 0 0 3 3 3 0 PaaX-like protein Peptidase_M16_M PF16187.5 EGR29906.1 - 3.2e-56 190.7 16.0 3.2e-56 190.7 16.0 2.4 2 1 0 2 2 2 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EGR29906.1 - 2.9e-38 131.2 1.6 1e-37 129.4 0.1 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGR29906.1 - 4.1e-23 82.4 8.3 4.1e-16 59.5 0.3 2.9 3 0 0 3 3 3 2 Peptidase M16 inactive domain Gemini_AL1_M PF08283.11 EGR29906.1 - 1.3 9.1 4.8 9.9 6.3 0.1 3.6 3 0 0 3 3 3 0 Geminivirus rep protein central domain peroxidase PF00141.23 EGR29908.1 - 9.6e-29 100.7 0.0 1.9e-28 99.7 0.0 1.4 1 1 0 1 1 1 1 Peroxidase Pkinase PF00069.25 EGR29909.1 - 3e-16 59.6 0.0 4e-16 59.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29909.1 - 4.5e-09 36.0 0.0 5.8e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR29909.1 - 2.6e-07 29.8 0.0 5.5e-07 28.7 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGR29909.1 - 0.033 13.6 0.1 0.053 12.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FAM150 PF15129.6 EGR29911.1 - 0.31 11.2 0.1 0.31 11.2 0.1 3.0 3 1 0 3 3 3 0 FAM150 family LRR_6 PF13516.6 EGR29911.1 - 0.59 10.3 6.5 4 7.7 0.7 4.0 5 0 0 5 5 5 0 Leucine Rich repeat Ribosomal_L34e PF01199.18 EGR29912.1 - 6.5e-37 125.7 7.9 6.5e-37 125.7 7.9 1.5 2 0 0 2 2 2 1 Ribosomal protein L34e Rad51 PF08423.11 EGR29912.1 - 0.043 13.1 0.4 0.047 12.9 0.4 1.1 1 0 0 1 1 1 0 Rad51 RRM_1 PF00076.22 EGR29913.1 - 1.6e-22 79.1 5.0 1.3e-08 34.5 0.0 3.9 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIF_beta PF02270.15 EGR29913.1 - 0.0044 17.1 0.1 0.018 15.1 0.1 2.1 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain RRM_3 PF08777.11 EGR29913.1 - 0.049 13.7 2.3 0.86 9.7 0.0 3.5 2 1 1 3 3 3 0 RNA binding motif CdiA_C PF18451.1 EGR29913.1 - 0.057 13.6 1.7 0.13 12.5 0.6 2.2 2 0 0 2 2 2 0 Contact-dependent growth inhibition CdiA C-terminal domain MFS_1 PF07690.16 EGR29914.1 - 2.3e-19 69.6 18.2 6.1e-12 45.1 2.9 2.3 2 1 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGR29914.1 - 7.7e-13 47.6 27.4 1.1e-10 40.5 5.6 3.1 1 1 3 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 EGR29914.1 - 0.00036 20.0 0.1 0.00036 20.0 0.1 2.1 2 1 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB UCH PF00443.29 EGR29915.1 - 1.9e-66 224.2 19.1 1.5e-65 221.2 19.1 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR29915.1 - 1.2e-11 44.8 39.1 3.3e-07 30.2 18.8 3.0 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-MYND PF01753.18 EGR29915.1 - 0.0071 16.4 16.2 0.0071 16.4 16.2 4.4 4 0 0 4 4 4 1 MYND finger Ribosomal_S27e PF01667.17 EGR29915.1 - 0.03 14.0 0.9 0.13 12.0 0.9 2.2 1 0 0 1 1 1 0 Ribosomal protein S27 zf-H2C2_2 PF13465.6 EGR29915.1 - 0.27 11.7 4.2 3.1 8.4 0.0 3.8 3 0 0 3 3 3 0 Zinc-finger double domain Kelch_6 PF13964.6 EGR29916.1 - 3.3e-05 24.0 0.2 0.079 13.3 0.0 2.6 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 EGR29916.1 - 0.0004 20.3 0.6 0.029 14.4 0.1 2.3 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_1 PF01344.25 EGR29916.1 - 0.002 17.7 0.8 0.83 9.3 0.2 2.4 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 EGR29916.1 - 0.026 14.8 0.1 9.9 6.6 0.0 2.3 2 0 0 2 2 2 0 Galactose oxidase, central domain Kelch_5 PF13854.6 EGR29916.1 - 0.072 13.1 0.1 0.2 11.7 0.1 1.7 1 0 0 1 1 1 0 Kelch motif Rad4 PF03835.15 EGR29916.1 - 0.19 11.4 0.2 0.53 10.0 0.2 1.7 1 1 0 1 1 1 0 Rad4 transglutaminase-like domain Pkinase PF00069.25 EGR29917.1 - 2.6e-41 141.7 2.9 4.1e-41 141.1 2.9 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29917.1 - 5.1e-31 107.9 0.3 5.1e-31 107.9 0.3 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR29917.1 - 0.00098 18.5 8.0 0.046 13.0 0.3 3.2 2 1 1 3 3 3 2 Kinase-like Kdo PF06293.14 EGR29917.1 - 0.031 13.6 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ferritin_2 PF13668.6 EGR29917.1 - 0.13 12.5 0.0 0.22 11.7 0.0 1.3 1 0 0 1 1 1 0 Ferritin-like domain Ribosomal_L29 PF00831.23 EGR29919.1 - 5.7e-13 48.6 1.3 5.7e-13 48.6 1.3 2.2 2 0 0 2 2 2 1 Ribosomal L29 protein Wbp11 PF09429.10 EGR29919.1 - 2.5 8.5 11.0 3.4 8.1 1.3 2.3 2 1 0 2 2 2 0 WW domain binding protein 11 Kelch_1 PF01344.25 EGR29920.1 - 5.4e-21 73.9 0.1 3.1e-12 45.9 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_6 PF13964.6 EGR29920.1 - 1.9e-18 66.0 1.3 6.8e-07 29.3 0.1 4.3 3 1 1 4 4 4 3 Kelch motif Kelch_2 PF07646.15 EGR29920.1 - 6.5e-13 48.1 0.3 0.00044 20.1 0.1 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 EGR29920.1 - 3.6e-12 46.1 0.1 0.00013 21.9 0.0 4.0 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EGR29920.1 - 3.3e-10 39.7 5.2 0.0058 16.6 0.1 4.2 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 EGR29920.1 - 3.8e-06 27.1 0.6 0.069 13.5 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain DUF2682 PF10909.8 EGR29920.1 - 1.3 9.5 11.2 0.045 14.2 3.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2682) Na_Ca_ex_C PF16494.5 EGR29920.1 - 7.9 7.0 11.4 0.34 11.4 3.6 2.3 1 1 0 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain PseudoU_synth_2 PF00849.22 EGR29922.1 - 2.2e-11 44.1 0.0 5.3e-10 39.6 0.0 2.1 1 1 0 1 1 1 1 RNA pseudouridylate synthase COG5 PF10392.9 EGR29922.1 - 0.045 13.9 0.0 0.064 13.4 0.0 1.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 AAA PF00004.29 EGR29923.1 - 4.2e-37 127.5 0.0 6.8e-37 126.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGR29923.1 - 3.4e-15 55.6 0.2 7.1e-14 51.3 0.0 2.9 2 1 1 3 3 3 1 AAA+ lid domain Vps4_C PF09336.10 EGR29923.1 - 1.5e-08 34.5 0.0 3.8e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 EGR29923.1 - 6.4e-06 26.2 0.4 3.6e-05 23.8 0.4 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGR29923.1 - 5.2e-05 23.1 0.0 9.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 EGR29923.1 - 0.00043 19.7 0.1 0.00082 18.8 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGR29923.1 - 0.0017 18.2 0.4 0.0043 16.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_2 PF07724.14 EGR29923.1 - 0.0024 18.0 0.0 0.0047 17.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EGR29923.1 - 0.0028 16.9 0.0 0.004 16.4 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EGR29923.1 - 0.0029 17.9 0.1 0.0081 16.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGR29923.1 - 0.0036 17.3 0.0 0.012 15.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 EGR29923.1 - 0.0043 17.2 0.0 0.0098 16.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGR29923.1 - 0.012 15.3 0.2 0.033 13.9 0.1 1.6 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_16 PF13191.6 EGR29923.1 - 0.034 14.5 0.1 0.064 13.6 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 EGR29923.1 - 0.051 13.8 0.0 0.099 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGR29923.1 - 0.054 14.1 0.2 0.054 14.1 0.2 3.3 3 1 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 EGR29923.1 - 0.072 12.8 0.8 0.73 9.5 0.0 2.6 3 1 0 3 3 3 0 Sigma-54 interaction domain TFIIA PF03153.13 EGR29923.1 - 0.075 13.0 9.7 0.26 11.3 9.7 1.7 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_7 PF12775.7 EGR29923.1 - 0.082 12.4 0.1 0.27 10.8 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region PhoH PF02562.16 EGR29923.1 - 0.085 12.3 0.1 0.15 11.5 0.1 1.3 1 0 0 1 1 1 0 PhoH-like protein NACHT PF05729.12 EGR29923.1 - 0.11 12.4 0.2 0.35 10.8 0.2 2.0 1 1 0 1 1 1 0 NACHT domain DUF4945 PF16303.5 EGR29924.1 - 0.029 14.3 1.0 0.077 12.9 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4945) ERGIC_N PF13850.6 EGR29924.1 - 0.096 13.0 4.6 0.69 10.3 1.1 3.4 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SPRY PF00622.28 EGR29925.1 - 2.1e-14 53.7 0.0 3.8e-14 52.8 0.0 1.4 1 0 0 1 1 1 1 SPRY domain zf-C3HC4_2 PF13923.6 EGR29925.1 - 8.9e-05 22.3 13.3 0.00025 20.8 13.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RAG1 PF10426.9 EGR29925.1 - 0.00016 21.8 0.2 0.00049 20.2 0.2 1.9 1 0 0 1 1 1 1 Recombination-activating protein 1 zinc-finger domain zf-RING_2 PF13639.6 EGR29925.1 - 0.0044 17.3 13.7 0.0044 17.3 13.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EGR29925.1 - 0.061 13.2 14.6 0.27 11.1 14.6 2.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EGR29925.1 - 0.095 12.6 6.7 0.26 11.2 6.7 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein RisS_PPD PF16524.5 EGR29925.1 - 0.11 12.7 0.2 0.2 11.9 0.2 1.3 1 0 0 1 1 1 0 Periplasmic domain of Sensor histidine kinase RisS zf-C3HC4_3 PF13920.6 EGR29925.1 - 3.2 7.7 17.7 0.77 9.7 13.4 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DNase_II PF03265.15 EGR29926.1 - 9.1e-86 288.1 7.4 1e-85 287.9 7.4 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II Thioredoxin PF00085.20 EGR29927.1 - 2.4e-06 27.5 0.0 3.1e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Gal_mutarotas_2 PF13802.6 EGR29928.1 - 0.89 9.9 3.8 35 4.8 3.8 2.3 1 1 0 1 1 1 0 Galactose mutarotase-like HATPase_c PF02518.26 EGR29929.1 - 1.3e-12 48.2 0.5 1.3e-12 48.2 0.5 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGR29929.1 - 4.6e-05 23.3 0.4 4.6e-05 23.3 0.4 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Peptidase_M50B PF13398.6 EGR29929.1 - 0.037 13.7 4.2 0.18 11.4 1.1 2.1 1 1 1 2 2 2 0 Peptidase M50B-like Atg14 PF10186.9 EGR29929.1 - 0.44 9.6 9.3 6.8 5.7 0.0 2.3 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 NAC PF01849.18 EGR29930.1 - 2.5e-19 69.0 0.1 3.9e-19 68.4 0.1 1.3 1 0 0 1 1 1 1 NAC domain CCDC106 PF15794.5 EGR29930.1 - 1.3 8.7 9.8 0.43 10.3 2.1 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 MFS_1 PF07690.16 EGR29931.1 - 2.7e-34 118.6 19.3 4e-34 118.1 19.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGR29931.1 - 0.00011 21.2 22.5 0.00013 21.0 0.6 3.0 3 0 0 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 EGR29931.1 - 0.078 11.3 0.5 4 5.7 0.1 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Radial_spoke PF04712.12 EGR29932.1 - 2.4e-18 66.3 0.1 5.1e-12 45.5 0.1 2.2 2 0 0 2 2 2 2 Radial spokehead-like protein Histone PF00125.24 EGR29933.1 - 1e-47 161.8 2.0 1.1e-47 161.6 2.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EGR29933.1 - 0.00012 22.4 0.1 0.00019 21.8 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 EGR29933.1 - 0.00082 20.0 0.9 0.001 19.7 0.9 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EGR29933.1 - 0.00095 19.3 0.7 0.0012 18.9 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 EGR29933.1 - 0.12 12.5 0.1 0.21 11.6 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Ion_trans PF00520.31 EGR29934.1 - 5.1e-13 48.8 20.4 5.1e-13 48.8 20.4 2.0 1 1 1 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 EGR29934.1 - 3.5e-07 30.1 11.4 3.5e-07 30.1 11.4 2.6 2 1 1 3 3 3 1 Ion channel RXLR_WY PF18634.1 EGR29934.1 - 1.3 9.0 3.9 0.6 10.1 0.4 2.3 3 0 0 3 3 3 0 RXLR phytopathogen effector protein WY-domain Pkinase PF00069.25 EGR29935.1 - 1.8e-65 221.0 0.1 2.8e-65 220.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain AAA PF00004.29 EGR29935.1 - 4.6e-43 146.8 0.1 1.3e-42 145.3 0.1 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Pkinase_Tyr PF07714.17 EGR29935.1 - 7.6e-35 120.4 0.2 3.8e-34 118.1 0.0 2.1 3 0 0 3 3 3 1 Protein tyrosine kinase AAA_lid_3 PF17862.1 EGR29935.1 - 5.4e-08 32.5 0.4 1.3e-07 31.3 0.4 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EGR29935.1 - 2.7e-05 24.3 0.1 8.6e-05 22.7 0.1 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_24 PF13479.6 EGR29935.1 - 5.4e-05 23.0 0.5 0.00016 21.5 0.5 1.8 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGR29935.1 - 9.2e-05 22.9 0.1 0.0051 17.2 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 EGR29935.1 - 0.00018 21.9 0.3 0.0036 17.7 0.3 2.9 1 1 0 1 1 1 1 RNA helicase RuvB_N PF05496.12 EGR29935.1 - 0.00019 21.2 0.0 0.00099 18.9 0.0 2.3 2 1 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain Pkinase_fungal PF17667.1 EGR29935.1 - 0.00045 19.1 0.0 0.0014 17.5 0.0 1.6 1 1 1 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGR29935.1 - 0.00071 19.0 0.0 0.0021 17.4 0.0 1.7 1 1 0 1 1 1 1 Kinase-like AAA_22 PF13401.6 EGR29935.1 - 0.00085 19.6 0.7 0.0082 16.4 0.3 2.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGR29935.1 - 0.00097 19.1 0.4 0.01 15.9 0.4 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGR29935.1 - 0.0027 17.1 0.1 0.012 15.0 0.0 2.2 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EGR29935.1 - 0.0094 16.0 0.1 0.072 13.1 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGR29935.1 - 0.018 14.5 1.9 0.034 13.6 0.1 2.5 2 2 1 3 3 3 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 EGR29935.1 - 0.025 14.3 0.1 0.092 12.4 0.0 2.1 2 1 0 2 2 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.17 EGR29935.1 - 0.031 14.0 0.0 0.073 12.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 EGR29935.1 - 0.034 14.3 0.0 0.088 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EGR29935.1 - 0.037 13.4 0.3 0.24 10.7 0.1 2.2 1 1 1 2 2 2 0 KaiC TniB PF05621.11 EGR29935.1 - 0.044 13.2 0.0 0.22 10.9 0.0 2.1 1 1 1 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 EGR29935.1 - 0.047 14.2 0.1 0.27 11.8 0.1 2.4 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EGR29935.1 - 0.085 12.8 0.2 1 9.3 0.1 2.4 2 0 0 2 2 2 0 NACHT domain PhoH PF02562.16 EGR29935.1 - 0.15 11.5 0.9 0.62 9.5 0.1 2.4 3 0 0 3 3 3 0 PhoH-like protein AAA_28 PF13521.6 EGR29935.1 - 0.16 12.2 0.0 0.39 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain FtsH_ext PF06480.15 EGR29935.1 - 0.33 11.3 2.3 0.91 9.9 1.0 2.3 1 1 1 2 2 2 0 FtsH Extracellular PHM7_cyt PF14703.6 EGR29936.1 - 7.7e-09 36.0 9.2 2.1e-08 34.6 5.7 2.9 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 EGR29936.1 - 1.4e-05 24.2 13.2 1.4e-05 24.2 13.2 3.3 2 2 1 3 3 3 1 Calcium-activated chloride channel Latarcin PF10279.9 EGR29936.1 - 0.48 10.9 6.8 2.1 8.8 6.9 2.1 1 1 0 1 1 1 0 Latarcin precursor FAD-SLDH PF12318.8 EGR29936.1 - 0.99 9.5 4.7 0.76 9.8 2.7 1.8 2 0 0 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase CREPT PF16566.5 EGR29936.1 - 2.9 8.0 13.7 6.3 7.0 12.9 1.9 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF745 PF05335.13 EGR29936.1 - 4.1 7.1 9.8 7.3 6.3 9.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) PspB PF06667.12 EGR29936.1 - 4.8 7.3 9.6 19 5.4 1.4 4.5 4 0 0 4 4 4 0 Phage shock protein B Peptidase_M16_M PF16187.5 EGR29937.1 - 1.2e-57 195.3 16.5 1.2e-57 195.3 16.5 3.3 3 1 0 3 3 3 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EGR29937.1 - 2e-37 128.4 0.1 2e-37 128.4 0.1 3.7 4 0 0 4 4 4 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGR29937.1 - 1e-19 71.3 12.1 5.9e-12 46.0 0.5 3.4 3 0 0 3 3 3 2 Peptidase M16 inactive domain Dpy-30 PF05186.13 EGR29938.1 - 3e-09 36.4 0.2 5.8e-09 35.5 0.2 1.5 1 0 0 1 1 1 1 Dpy-30 motif AAA_17 PF13207.6 EGR29938.1 - 1.7e-06 28.5 2.0 1.7e-06 28.5 2.0 3.9 2 2 1 3 3 3 1 AAA domain AAA_18 PF13238.6 EGR29938.1 - 1.9e-05 25.2 0.2 1.9e-05 25.2 0.2 4.1 1 1 2 3 3 2 1 AAA domain ADK PF00406.22 EGR29938.1 - 2.7e-05 24.3 0.0 2.7e-05 24.3 0.0 3.6 3 1 0 3 3 3 1 Adenylate kinase AAA_28 PF13521.6 EGR29938.1 - 0.001 19.3 0.0 0.0042 17.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain Hydin_ADK PF17213.3 EGR29938.1 - 0.0019 18.5 0.0 0.0019 18.5 0.0 2.7 1 1 0 2 2 2 1 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 EGR29938.1 - 0.0022 18.2 0.0 0.0095 16.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 EGR29938.1 - 0.0038 17.0 0.0 0.011 15.4 0.0 1.8 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 EGR29938.1 - 0.004 17.6 1.3 0.01 16.3 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGR29938.1 - 0.018 15.5 0.3 0.13 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain RuvB_N PF05496.12 EGR29938.1 - 0.029 14.1 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 EGR29938.1 - 0.035 14.0 0.1 0.035 14.0 0.1 2.2 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.6 EGR29938.1 - 0.094 13.0 1.8 0.28 11.5 0.0 2.5 2 1 0 2 2 2 0 AAA domain SKI PF01202.22 EGR29938.1 - 0.24 11.5 0.1 0.24 11.5 0.1 3.6 2 1 1 3 3 3 0 Shikimate kinase Pkinase PF00069.25 EGR29939.1 - 5.9e-38 130.7 6.1 7.4e-38 130.4 6.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29939.1 - 7.4e-28 97.5 3.4 3.7e-27 95.2 3.3 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR29939.1 - 5.5e-06 25.4 0.8 6.3e-05 21.9 0.1 2.0 1 1 1 2 2 2 1 Fungal protein kinase DUF2357 PF09823.9 EGR29939.1 - 0.0027 17.0 0.6 0.0043 16.3 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2357) APH PF01636.23 EGR29939.1 - 0.0043 17.0 0.0 0.066 13.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGR29939.1 - 0.0044 16.7 3.3 0.027 14.1 0.7 2.1 1 1 1 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EGR29939.1 - 0.019 14.3 3.3 1.1 8.6 3.3 2.2 1 1 0 1 1 1 0 Kinase-like ZinT PF09223.11 EGR29939.1 - 0.19 11.6 4.3 0.28 11.0 4.3 1.2 1 0 0 1 1 1 0 ZinT (YodA) periplasmic lipocalin-like zinc-recruitment DUF4860 PF16152.5 EGR29939.1 - 0.79 9.6 4.4 7.6 6.5 0.4 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4860) Kinesin PF00225.23 EGR29940.1 - 2.7e-103 345.4 4.5 2.7e-103 345.4 4.5 5.3 3 2 3 6 6 6 1 Kinesin motor domain Microtub_bd PF16796.5 EGR29940.1 - 1e-22 80.7 0.8 1e-22 80.7 0.8 7.0 3 1 3 7 7 7 1 Microtubule binding WD40 PF00400.32 EGR29940.1 - 7e-11 42.5 2.3 0.21 12.5 0.0 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat Pkinase PF00069.25 EGR29941.1 - 2.3e-26 92.7 0.1 2.3e-26 92.7 0.1 2.0 2 1 0 2 2 2 1 Protein kinase domain EF-hand_7 PF13499.6 EGR29941.1 - 1.6e-16 60.5 14.5 1.6e-08 34.9 3.2 3.9 3 0 0 3 3 3 3 EF-hand domain pair Pkinase_Tyr PF07714.17 EGR29941.1 - 1.1e-13 51.0 0.0 2.4e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 EGR29941.1 - 5.8e-11 41.1 19.3 4.5e-06 25.8 1.6 4.4 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 EGR29941.1 - 4.3e-10 38.7 15.9 2.9e-05 23.7 0.8 4.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 EGR29941.1 - 2e-07 30.7 9.2 3.1e-06 26.9 0.8 3.5 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EGR29941.1 - 1.3e-05 24.5 10.2 0.01 15.3 1.5 3.3 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 EGR29941.1 - 0.00036 20.4 9.2 0.067 13.1 0.9 2.9 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand p25-alpha PF05517.12 EGR29941.1 - 0.001 19.3 17.8 0.0043 17.2 3.4 3.4 1 1 2 3 3 3 2 p25-alpha Herpes_BLRF2 PF05812.12 EGR29941.1 - 0.027 14.6 0.8 2.9 8.1 0.0 2.3 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein FtsQ PF03799.15 EGR29941.1 - 0.067 14.0 1.3 0.17 12.7 0.4 2.1 2 0 0 2 2 2 0 Cell division protein FtsQ RST PF12174.8 EGR29941.1 - 0.13 12.2 0.1 0.13 12.2 0.1 3.3 3 1 1 4 4 4 0 RCD1-SRO-TAF4 (RST) plant domain T4_Gp59_N PF08993.10 EGR29941.1 - 0.22 11.9 7.2 10 6.6 0.5 3.8 3 1 0 3 3 3 0 T4 gene Gp59 loader of gp41 DNA helicase DUF2680 PF10925.8 EGR29942.1 - 0.02 14.9 0.8 0.02 14.9 0.8 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2680) Ribosomal_S15 PF00312.22 EGR29942.1 - 0.023 14.9 3.4 0.1 12.8 0.9 2.6 2 0 0 2 2 2 0 Ribosomal protein S15 PP2C PF00481.21 EGR29943.1 - 3.2e-43 148.2 0.0 3.2e-43 148.2 0.0 2.3 2 1 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGR29943.1 - 0.0003 20.5 0.0 0.0012 18.5 0.0 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C ETF PF01012.21 EGR29944.1 - 2.1e-37 128.8 0.0 2.6e-37 128.5 0.0 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain SPO22 PF08631.10 EGR29945.1 - 0.0071 15.9 5.5 0.023 14.2 5.5 2.0 1 1 0 1 1 1 1 Meiosis protein SPO22/ZIP4 like FDX-ACB PF03147.14 EGR29945.1 - 0.05 14.0 2.9 0.071 13.5 0.2 2.7 2 1 0 2 2 2 0 Ferredoxin-fold anticodon binding domain DFP PF04127.15 EGR29946.1 - 1.9e-14 53.9 0.0 4.1e-09 36.5 0.0 2.3 1 1 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Abhydro_lipase PF04083.16 EGR29946.1 - 0.043 13.4 1.1 3.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Partial alpha/beta-hydrolase lipase region H_PPase PF03030.16 EGR29947.1 - 9.1e-242 804.3 27.4 1.2e-241 804.0 27.4 1.0 1 0 0 1 1 1 1 Inorganic H+ pyrophosphatase YrhC PF14143.6 EGR29947.1 - 3.1 7.9 5.4 1.1 9.4 0.1 3.1 3 0 0 3 3 3 0 YrhC-like protein Pyr_redox_2 PF07992.14 EGR29949.1 - 3.2e-31 108.6 0.1 4.9e-31 108.0 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGR29949.1 - 2.2e-12 47.3 0.2 5.3e-12 46.1 0.2 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Reductase_C PF14759.6 EGR29949.1 - 2.3e-08 34.4 0.1 4.8e-08 33.5 0.1 1.6 1 0 0 1 1 1 1 Reductase C-terminal DUF4522 PF15022.6 EGR29949.1 - 0.0097 16.2 1.1 0.11 12.8 0.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4522) WD40 PF00400.32 EGR29950.1 - 4.3e-12 46.3 2.6 0.39 11.7 0.1 8.4 9 0 0 9 9 9 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR29950.1 - 7.2e-05 23.0 0.7 4.5 7.6 0.0 6.1 4 1 2 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain NIF PF03031.18 EGR29951.1 - 3.5e-44 150.3 8.3 4.5e-44 150.0 2.2 2.2 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase PNK3P PF08645.11 EGR29951.1 - 6.4 6.5 9.5 5.2 6.7 5.0 2.4 2 1 0 2 2 2 0 Polynucleotide kinase 3 phosphatase DSHCT PF08148.12 EGR29952.1 - 6.2e-51 172.3 0.2 6.2e-51 172.3 0.2 2.0 2 0 0 2 2 2 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 EGR29952.1 - 4.3e-32 112.1 27.2 1.4e-24 87.4 19.5 2.7 1 1 1 2 2 2 2 rRNA-processing arch domain Helicase_C PF00271.31 EGR29952.1 - 1.6e-06 28.4 0.0 1.6e-06 28.4 0.0 2.7 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGR29952.1 - 0.00016 21.5 1.3 0.0016 18.2 0.0 3.0 3 0 0 3 3 3 1 DEAD/DEAH box helicase DUF3800 PF12686.7 EGR29952.1 - 2.5 8.8 5.4 48 4.6 5.4 3.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Peptidase_S46 PF10459.9 EGR29952.1 - 8.1 4.9 11.9 0.43 9.2 0.1 2.2 1 1 0 2 2 2 0 Peptidase S46 Coatomer_WDAD PF04053.14 EGR29953.1 - 9.9e-122 407.2 16.8 2.4e-121 405.9 16.8 1.7 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 EGR29953.1 - 3.8e-30 103.5 8.3 8e-08 32.8 0.1 7.5 8 0 0 8 8 8 5 WD domain, G-beta repeat SpoU_methylase PF00588.19 EGR29953.1 - 6.6e-26 91.2 0.0 4.4e-25 88.5 0.0 2.4 2 0 0 2 2 2 1 SpoU rRNA Methylase family ANAPC4_WD40 PF12894.7 EGR29953.1 - 2.3e-06 27.8 2.2 0.35 11.2 0.1 6.0 2 1 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGR29953.1 - 0.013 15.5 0.2 4.7 7.3 0.0 4.0 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Crystall_2 PF09076.10 EGR29953.1 - 0.015 15.2 0.1 0.05 13.5 0.1 1.8 1 0 0 1 1 1 0 Beta/Gamma crystallin TPR_8 PF13181.6 EGR29953.1 - 0.026 14.7 2.5 11 6.5 0.0 4.0 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGR29953.1 - 0.54 10.8 4.3 14 6.3 0.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Dynamin_M PF01031.20 EGR29954.1 - 7.8e-91 304.2 8.5 7.8e-91 304.2 8.5 2.9 1 1 0 2 2 2 1 Dynamin central region GED PF02212.18 EGR29954.1 - 2.7e-22 78.7 4.9 2.7e-22 78.7 4.9 3.6 4 0 0 4 4 4 1 Dynamin GTPase effector domain Dynamin_N PF00350.23 EGR29954.1 - 0.0012 18.9 0.0 0.0012 18.9 0.0 3.8 2 1 0 2 2 2 1 Dynamin family Peptidase_S15 PF02129.18 EGR29954.1 - 0.54 9.8 4.9 18 4.8 5.6 2.3 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) DUF4637 PF15470.6 EGR29954.1 - 0.64 9.7 5.3 1.2 8.8 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF4407 PF14362.6 EGR29954.1 - 9.1 5.5 10.0 15 4.8 10.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RRM_1 PF00076.22 EGR29956.1 - 8.2e-15 54.4 0.1 1.4e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 EGR29956.1 - 8.8e-07 28.7 3.2 1.5e-06 28.0 3.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EGR29956.1 - 0.00011 21.9 4.1 0.00024 20.8 4.1 1.6 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger Macoilin PF09726.9 EGR29956.1 - 0.00016 20.4 8.9 0.00018 20.3 8.9 1.1 1 0 0 1 1 1 1 Macoilin family zf-CCHC_3 PF13917.6 EGR29956.1 - 0.0015 18.4 3.9 0.0042 17.0 3.9 1.9 1 1 0 1 1 1 1 Zinc knuckle SR-25 PF10500.9 EGR29956.1 - 0.0073 15.9 29.4 0.01 15.5 29.4 1.2 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein zf-CCHC_4 PF14392.6 EGR29956.1 - 0.0089 15.7 0.2 0.017 14.9 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle Apt1 PF10351.9 EGR29956.1 - 0.02 13.8 10.8 0.026 13.4 10.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Nup35_RRM_2 PF14605.6 EGR29956.1 - 0.028 14.4 0.2 0.047 13.7 0.2 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Presenilin PF01080.17 EGR29956.1 - 0.055 12.2 6.0 0.075 11.8 6.0 1.2 1 0 0 1 1 1 0 Presenilin DUF1635 PF07795.11 EGR29956.1 - 0.17 11.8 8.2 0.29 11.0 8.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Rrn6 PF10214.9 EGR29956.1 - 2.9 6.2 27.7 7.8 4.9 24.6 2.0 2 0 0 2 2 2 0 RNA polymerase I-specific transcription-initiation factor NPR3 PF03666.13 EGR29956.1 - 4.3 6.0 17.3 5.9 5.6 17.3 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 PI3K_1B_p101 PF10486.9 EGR29956.1 - 6.6 4.4 12.7 8.3 4.1 12.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit zf-RING_2 PF13639.6 EGR29957.1 - 2e-08 34.4 6.2 3.7e-08 33.6 6.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGR29957.1 - 3.1e-07 30.3 4.4 6.1e-07 29.4 4.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGR29957.1 - 1.3e-06 28.1 2.9 2.8e-06 27.1 2.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGR29957.1 - 1.9e-05 24.4 4.4 5.1e-05 23.1 4.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGR29957.1 - 3.4e-05 23.5 6.2 8.1e-05 22.3 6.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EGR29957.1 - 0.00049 20.3 2.8 0.0014 18.9 2.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGR29957.1 - 0.00078 19.4 5.3 0.0019 18.1 5.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Zf_RING PF16744.5 EGR29957.1 - 0.0013 18.8 2.9 0.0029 17.7 2.9 1.5 1 0 0 1 1 1 1 KIAA1045 RING finger zf-C3HC4_4 PF15227.6 EGR29957.1 - 0.0047 17.1 3.2 0.01 15.9 3.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EGR29957.1 - 0.0087 16.1 1.3 0.021 14.9 1.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGR29957.1 - 0.015 14.9 2.8 0.027 14.1 2.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EGR29957.1 - 0.035 14.3 6.0 0.14 12.4 6.0 2.0 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 EGR29957.1 - 0.073 13.0 6.9 0.14 12.1 6.9 1.5 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_3 PF13920.6 EGR29957.1 - 0.4 10.6 4.7 0.8 9.6 4.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Imm51 PF15595.6 EGR29957.1 - 0.74 9.8 5.9 16 5.5 0.0 3.3 3 0 0 3 3 3 0 Immunity protein 51 zf-Nse PF11789.8 EGR29957.1 - 0.86 9.5 11.0 0.58 10.0 7.5 2.6 2 1 1 3 3 3 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_1 PF14446.6 EGR29957.1 - 1.5 8.8 5.6 0.47 10.4 2.5 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.6 EGR29957.1 - 2.8 8.3 7.6 5 7.4 5.9 2.4 1 1 2 3 3 3 0 PHD-like zinc-binding domain MORN PF02493.20 EGR29958.1 - 1.9e-20 71.5 22.4 6.5e-08 32.0 0.5 5.3 5 0 0 5 5 5 4 MORN repeat ABC_membrane PF00664.23 EGR29961.1 - 5.1e-48 164.1 15.9 5.1e-48 164.1 15.9 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGR29961.1 - 3.9e-33 114.9 0.0 3.9e-33 114.9 0.0 4.1 3 1 1 4 4 4 1 ABC transporter RsgA_GTPase PF03193.16 EGR29961.1 - 0.00029 20.8 2.3 0.0015 18.4 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA PF00004.29 EGR29961.1 - 0.0039 17.6 0.2 0.0039 17.6 0.2 3.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGR29961.1 - 0.01 16.1 0.6 0.26 11.5 0.6 2.8 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGR29961.1 - 0.033 13.9 0.0 0.17 11.6 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EGR29961.1 - 0.039 13.5 0.0 0.54 9.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGR29961.1 - 0.12 12.8 0.1 0.12 12.8 0.1 2.7 2 2 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 EGR29961.1 - 1.1 9.8 0.0 1.1 9.8 0.0 3.7 2 1 0 3 3 3 0 AAA domain Peptidase_C1 PF00112.23 EGR29962.1 - 9.8e-71 238.3 5.4 9.8e-71 238.3 5.4 3.3 4 0 0 4 4 4 1 Papain family cysteine protease Pkinase PF00069.25 EGR29962.1 - 2.2e-23 83.0 3.8 2.2e-23 83.0 3.8 2.8 2 1 0 2 2 2 1 Protein kinase domain MORN PF02493.20 EGR29962.1 - 6.6e-20 69.8 20.9 4.5e-07 29.4 0.5 5.6 5 0 0 5 5 5 4 MORN repeat Pkinase_Tyr PF07714.17 EGR29962.1 - 1.6e-15 57.1 1.5 1.6e-15 57.1 1.5 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase EHD_N PF16880.5 EGR29962.1 - 0.041 13.8 0.0 0.15 12.0 0.0 1.9 1 0 0 1 1 1 0 N-terminal EH-domain containing protein PI-PLC-X PF00388.19 EGR29964.1 - 7.2e-60 200.8 0.4 7.2e-60 200.8 0.4 2.9 3 0 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EGR29964.1 - 1.5e-26 93.0 0.0 1.5e-26 93.0 0.0 3.2 3 1 0 3 3 3 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EGR29964.1 - 1.7e-13 50.8 0.1 4.2e-13 49.5 0.1 1.7 1 0 0 1 1 1 1 C2 domain EF-hand_7 PF13499.6 EGR29964.1 - 3.4e-10 40.2 7.7 1.5e-07 31.8 0.9 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR29964.1 - 4.1e-10 38.5 3.9 3.7e-05 23.0 0.3 3.4 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EGR29964.1 - 2.5e-08 33.2 6.9 0.0001 21.9 0.2 4.3 4 0 0 4 4 4 2 EF-hand domain EF-hand_10 PF14788.6 EGR29964.1 - 1.9e-06 27.6 1.8 6.3e-06 26.0 1.5 2.1 1 1 1 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGR29964.1 - 0.0021 17.4 2.7 0.0023 17.3 0.3 2.4 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 EGR29964.1 - 0.0069 16.7 0.7 0.0069 16.7 0.7 3.6 3 0 0 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 EGR29964.1 - 0.0092 15.8 0.2 0.054 13.4 0.1 2.3 1 1 1 2 2 2 1 EF-hand domain pair ALMT PF11744.8 EGR29964.1 - 1.5 7.5 13.9 3.4 6.4 13.9 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF1765 PF08578.10 EGR29965.1 - 1.7e-21 77.0 15.9 1.7e-21 77.0 15.9 3.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1765) Carb_kinase PF01256.17 EGR29966.1 - 2.1e-40 138.8 0.0 5.6e-31 107.9 0.0 2.1 2 0 0 2 2 2 2 Carbohydrate kinase DUF2303 PF10065.9 EGR29967.1 - 0.00098 18.4 2.5 0.0014 17.8 2.5 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2303) Guanylate_cyc PF00211.20 EGR29968.1 - 8.4e-16 58.1 0.7 2e-15 56.9 0.0 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain HMG_box PF00505.19 EGR29969.1 - 5.1e-10 39.6 2.0 5.1e-10 39.6 2.0 2.9 1 1 2 3 3 3 1 HMG (high mobility group) box zf-CSL PF05207.13 EGR29971.1 - 7.6e-22 76.8 0.3 9.1e-22 76.6 0.3 1.1 1 0 0 1 1 1 1 CSL zinc finger zf-RING_4 PF14570.6 EGR29971.1 - 0.0046 16.7 0.3 0.0069 16.1 0.3 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn-ribbon_8 PF09723.10 EGR29971.1 - 0.035 14.2 0.1 0.06 13.5 0.1 1.4 1 0 0 1 1 1 0 Zinc ribbon domain Pkinase PF00069.25 EGR29972.1 - 3.2e-64 216.8 2.0 3.2e-64 216.8 2.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29972.1 - 2.1e-37 128.8 0.3 2.1e-37 128.8 0.3 1.8 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR29972.1 - 1.4e-05 24.1 3.8 3.4e-05 22.8 3.8 1.6 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR29972.1 - 0.01 15.2 0.1 0.019 14.4 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RL PF17797.1 EGR29972.1 - 0.034 14.1 0.8 0.12 12.4 0.8 1.9 1 0 0 1 1 1 0 RL domain FTA2 PF13095.6 EGR29972.1 - 0.26 10.9 8.3 1.9 8.1 0.2 3.1 1 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 ATP-synt_ab PF00006.25 EGR29973.1 - 1.7e-37 129.2 0.0 2.6e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGR29973.1 - 3e-23 82.1 2.5 5.4e-23 81.3 2.5 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 EGR29973.1 - 0.0044 16.2 0.0 0.0074 15.5 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain RsgA_GTPase PF03193.16 EGR29973.1 - 0.017 15.0 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 EGR29973.1 - 0.018 14.9 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 EGR29973.1 - 0.025 14.5 0.0 0.052 13.5 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EGR29973.1 - 0.042 14.2 0.1 0.097 13.0 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGR29973.1 - 0.061 13.6 0.1 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGR29973.1 - 0.084 13.3 0.0 0.14 12.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 EGR29973.1 - 0.088 12.1 0.0 0.19 11.1 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_19 PF13245.6 EGR29973.1 - 0.096 13.0 0.1 0.19 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGR29973.1 - 0.11 12.9 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGR29973.1 - 0.17 11.4 0.2 0.42 10.1 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region ABC_tran PF00005.27 EGR29973.1 - 0.18 12.3 0.2 0.44 11.1 0.1 1.7 2 0 0 2 2 2 0 ABC transporter AAA_28 PF13521.6 EGR29973.1 - 0.19 12.0 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TauE PF01925.19 EGR29974.1 - 1.9e-08 34.2 4.2 2.4e-08 33.9 4.2 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE TauE PF01925.19 EGR29975.1 - 7.3e-11 42.2 4.6 8.6e-11 41.9 4.6 1.0 1 0 0 1 1 1 1 Sulfite exporter TauE/SafE GM_CSF PF01109.17 EGR29975.1 - 0.025 14.8 0.0 0.041 14.0 0.0 1.3 1 0 0 1 1 1 0 Granulocyte-macrophage colony-stimulating factor DUF4131 PF13567.6 EGR29975.1 - 0.25 11.0 5.0 3.3 7.4 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) HKR_ArcB_TM PF18415.1 EGR29975.1 - 1.3 9.8 8.7 5.3 7.9 0.9 2.2 2 0 0 2 2 2 0 Histidine kinase receptor ArcB trans-membrane domain CCB1 PF12046.8 EGR29976.1 - 1.1 8.5 4.0 3.2 7.1 4.0 1.8 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B WD40 PF00400.32 EGR29977.1 - 1.8e-20 72.9 2.4 8.9e-05 23.2 0.3 5.4 5 0 0 5 5 5 5 WD domain, G-beta repeat PALB2_WD40 PF16756.5 EGR29977.1 - 0.031 13.2 0.2 0.84 8.5 0.0 2.4 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Aminotran_5 PF00266.19 EGR29978.1 - 1.2e-20 73.8 0.0 2.2e-20 72.9 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Cyclin_C PF02984.19 EGR29978.1 - 3.7e-05 23.8 4.1 0.00017 21.7 0.9 2.5 1 1 1 2 2 2 1 Cyclin, C-terminal domain Cyclin_N PF00134.23 EGR29978.1 - 8.7e-05 22.3 1.0 0.0041 16.9 0.2 2.5 1 1 1 2 2 2 2 Cyclin, N-terminal domain Cmc1 PF08583.10 EGR29979.1 - 2.2e-07 30.8 5.0 3.5e-07 30.1 5.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ndufs5 PF10200.9 EGR29979.1 - 0.026 14.8 4.5 0.04 14.2 4.5 1.3 1 0 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa DDHD PF02862.17 EGR29980.1 - 0.00092 19.4 0.1 0.00092 19.4 0.1 5.2 1 1 2 3 3 3 1 DDHD domain Lipocalin_2 PF08212.12 EGR29982.1 - 1.6e-11 44.3 0.0 2.2e-11 43.9 0.0 1.1 1 0 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 EGR29982.1 - 0.00013 22.2 0.0 0.00016 21.9 0.0 1.1 1 0 0 1 1 1 1 Lipocalin / cytosolic fatty-acid binding protein family S1 PF00575.23 EGR29983.1 - 2.6e-19 69.3 36.9 0.014 15.7 0.0 12.2 12 1 1 13 13 13 8 S1 RNA binding domain Suf PF05843.14 EGR29983.1 - 1.5e-06 28.5 19.7 4.7e-06 26.8 6.0 5.0 2 1 0 4 4 4 2 Suppressor of forked protein (Suf) TPR_6 PF13174.6 EGR29983.1 - 0.051 14.2 0.4 0.48 11.2 0.1 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGR29983.1 - 0.24 12.3 0.0 1.7e+02 3.4 0.0 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat MT-A70 PF05063.14 EGR29984.1 - 2e-37 128.8 0.5 2e-37 128.8 0.5 2.0 2 0 0 2 2 2 1 MT-A70 ZZ PF00569.17 EGR29984.1 - 1.9e-19 69.2 61.5 5.8e-08 32.4 7.7 4.5 4 0 0 4 4 4 4 Zinc finger, ZZ type AT_hook PF02178.19 EGR29984.1 - 0.16 11.9 0.7 0.42 10.7 0.7 1.7 1 0 0 1 1 1 0 AT hook motif Dopey_N PF04118.14 EGR29985.1 - 5e-92 308.3 12.8 5e-92 308.3 12.8 6.3 3 3 0 4 4 4 1 Dopey, N-terminal Lambda_Bor PF06291.11 EGR29985.1 - 0.31 11.1 0.0 0.31 11.1 0.0 2.2 2 0 0 2 2 2 0 Bor protein TFIIA PF03153.13 EGR29985.1 - 3.3 7.6 38.7 3.4 7.6 14.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit cNMP_binding PF00027.29 EGR29986.1 - 3.2e-15 56.0 0.1 2.7e-05 24.2 0.1 3.2 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Copine PF07002.16 EGR29988.1 - 1.4e-51 175.0 0.1 2.1e-51 174.5 0.1 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 EGR29988.1 - 1.5e-21 76.6 1.1 2.5e-11 43.8 0.1 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EGR29988.1 - 7.3e-08 32.8 0.1 1.8e-07 31.5 0.0 1.7 2 0 0 2 2 2 1 vWA found in TerF C terminus PLDc_2 PF13091.6 EGR29989.1 - 1e-34 119.3 7.2 7.5e-26 90.6 0.9 3.0 2 1 1 3 3 3 2 PLD-like domain PLDc PF00614.22 EGR29989.1 - 4e-06 26.8 1.9 0.006 16.7 0.0 2.7 3 0 0 3 3 3 2 Phospholipase D Active site motif Regulator_TrmB PF11495.8 EGR29989.1 - 0.00026 20.3 0.1 0.044 13.0 0.0 2.4 2 0 0 2 2 2 2 Archaeal transcriptional regulator TrmB ILEI PF15711.5 EGR29989.1 - 0.056 13.9 0.3 0.2 12.2 0.1 2.1 2 0 0 2 2 2 0 Interleukin-like EMT inducer EF1G PF00647.19 EGR29989.1 - 1.1 9.3 9.4 0.11 12.6 2.7 2.7 2 1 0 2 2 2 0 Elongation factor 1 gamma, conserved domain SHIPPO-rpt PF07004.12 EGR29990.1 - 4.2e-07 30.6 0.4 0.0094 16.8 0.1 2.3 2 0 0 2 2 2 2 Sperm-tail PG-rich repeat Pkinase PF00069.25 EGR29991.1 - 2.6e-56 190.9 0.0 3.8e-56 190.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29991.1 - 9.3e-33 113.6 0.0 1.2e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR29991.1 - 0.0001 21.3 0.3 0.0002 20.2 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGR29991.1 - 0.00014 21.3 0.3 0.00036 19.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGR29991.1 - 0.18 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sdh5 PF03937.16 EGR29992.1 - 3.8e-07 30.0 0.1 4.5e-07 29.7 0.1 1.1 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase tRNA-synt_1d PF00750.19 EGR29993.1 - 1.2e-35 123.1 0.3 1.2e-35 123.1 0.3 1.6 1 1 1 2 2 2 1 tRNA synthetases class I (R) Arg_tRNA_synt_N PF03485.16 EGR29993.1 - 7.6e-06 26.4 0.5 3.7e-05 24.2 0.4 2.1 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain DUF5492 PF17596.2 EGR29993.1 - 0.018 15.3 0.8 8.4 6.8 0.1 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5492) tRNA-synt_1 PF00133.22 EGR29993.1 - 0.02 13.2 0.2 0.072 11.3 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EGR29993.1 - 0.026 13.3 0.2 0.41 9.3 0.0 2.1 1 1 1 2 2 2 0 tRNA synthetases class I (M) Pre-PUA PF17832.1 EGR29993.1 - 0.067 13.9 0.6 0.19 12.4 0.6 1.8 1 0 0 1 1 1 0 Pre-PUA-like domain tRNA-synt_1d PF00750.19 EGR29994.1 - 2e-58 198.0 0.5 4e-57 193.7 0.1 2.5 2 1 0 2 2 2 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EGR29994.1 - 1.8e-25 89.4 0.5 3.7e-25 88.4 0.5 1.5 1 0 0 1 1 1 1 DALR anticodon binding domain CHASE6_C PF17150.4 EGR29994.1 - 0.057 14.1 1.8 0.19 12.4 0.1 2.3 2 0 0 2 2 2 0 C-terminal domain of two-partite extracellular sensor domain EF-hand_7 PF13499.6 EGR29995.1 - 2.2e-08 34.4 1.1 4.5e-07 30.2 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_9 PF14658.6 EGR29995.1 - 8.1e-07 29.3 0.0 1.9e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 EGR29995.1 - 2.1e-06 26.9 2.1 1.5e-05 24.2 0.1 2.9 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 EGR29995.1 - 2.7e-06 26.9 1.7 0.00014 21.5 0.2 2.8 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 EGR29995.1 - 0.006 16.4 0.2 9.9 6.1 0.0 3.5 4 0 0 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EGR29995.1 - 0.051 13.1 1.1 0.051 13.1 1.1 2.0 2 0 0 2 2 2 0 EF hand FGAR-AT_linker PF18072.1 EGR29995.1 - 0.12 13.0 0.0 0.32 11.5 0.0 1.8 1 0 0 1 1 1 0 Formylglycinamide ribonucleotide amidotransferase linker domain RCC1 PF00415.18 EGR29996.1 - 7.5e-37 125.7 5.0 3.2e-11 43.7 0.0 4.2 4 0 0 4 4 4 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR29996.1 - 2.4e-25 87.7 3.6 6e-08 32.3 0.2 5.0 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.25 EGR29997.1 - 1.7e-06 27.6 0.0 2.3e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29997.1 - 0.057 12.7 0.0 0.079 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase DNA_pol_phi PF04931.13 EGR29998.1 - 3.1e-11 42.2 25.2 2.6e-10 39.1 25.2 1.9 1 1 0 1 1 1 1 DNA polymerase phi MOR2-PAG1_C PF14225.6 EGR29998.1 - 0.2 11.5 2.7 5.6 6.7 0.4 2.6 1 1 1 2 2 2 0 Cell morphogenesis C-terminal DUF4298 PF14131.6 EGR29998.1 - 0.88 9.6 12.5 0.037 14.0 2.8 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) DUF1041 PF06292.17 EGR29998.1 - 1.4 9.4 16.9 0.18 12.2 3.9 2.9 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1041) NAD_binding_6 PF08030.12 EGR29998.1 - 8.7 6.5 8.1 15 5.7 7.7 1.7 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Pkinase PF00069.25 EGR29999.1 - 1.6e-69 234.2 1.3 3e-69 233.3 1.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR29999.1 - 1.1e-43 149.4 0.4 1.8e-43 148.7 0.4 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase NIF PF03031.18 EGR29999.1 - 2.7e-43 147.4 3.4 6.5e-43 146.2 3.4 1.7 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pkinase_fungal PF17667.1 EGR29999.1 - 9.4e-05 21.4 0.0 0.00019 20.3 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGR29999.1 - 0.00061 19.2 0.1 0.004 16.5 0.0 2.2 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 EGR29999.1 - 0.007 16.3 0.0 0.024 14.6 0.0 1.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR29999.1 - 0.0078 15.6 0.6 0.014 14.7 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF676 PF05057.14 EGR30000.1 - 3.4e-46 157.5 0.0 8.7e-46 156.2 0.0 1.7 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGR30000.1 - 9.9e-08 32.1 0.0 9.9e-08 32.1 0.0 2.2 3 0 0 3 3 3 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 EGR30000.1 - 2.7e-06 27.3 0.0 7.9e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 PGAP1-like protein DUF1643 PF07799.12 EGR30000.1 - 0.051 13.7 0.6 0.15 12.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1643) RNA_pol_Rpb6 PF01192.22 EGR30001.1 - 1.4e-15 56.9 0.1 3.1e-15 55.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb6 Nop14 PF04147.12 EGR30001.1 - 0.003 15.9 15.5 0.003 15.8 15.5 1.0 1 0 0 1 1 1 1 Nop14-like family DUF4549 PF15082.6 EGR30001.1 - 0.054 13.3 0.4 0.078 12.8 0.4 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4549) Mpp10 PF04006.12 EGR30001.1 - 0.13 10.7 18.2 0.14 10.6 18.2 1.1 1 0 0 1 1 1 0 Mpp10 protein SDA1 PF05285.12 EGR30001.1 - 0.62 9.4 19.8 0.64 9.4 19.8 1.1 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EGR30001.1 - 0.76 8.0 14.5 0.81 7.9 14.5 1.0 1 0 0 1 1 1 0 CDC45-like protein FAM60A PF15396.6 EGR30001.1 - 0.95 9.4 4.2 1.2 9.1 4.2 1.3 1 0 0 1 1 1 0 Protein Family FAM60A Cwf_Cwc_15 PF04889.12 EGR30001.1 - 1.2 8.9 19.5 1.5 8.5 19.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Presenilin PF01080.17 EGR30001.1 - 7.6 5.2 5.8 8.7 5.0 5.8 1.1 1 0 0 1 1 1 0 Presenilin Tub PF01167.18 EGR30002.1 - 2.4e-80 269.7 0.0 2.4e-80 269.7 0.0 2.8 2 1 0 2 2 2 1 Tub family Pkinase PF00069.25 EGR30003.1 - 4.8e-70 235.9 1.2 4.8e-70 235.9 1.2 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30003.1 - 1e-34 120.0 0.4 2.6e-34 118.7 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR30003.1 - 0.0013 18.1 0.0 0.0013 18.1 0.0 2.1 3 0 0 3 3 3 1 Kinase-like TFA2_Winged_2 PF18121.1 EGR30003.1 - 1.8 8.3 4.7 1.7 8.4 0.1 3.0 3 0 0 3 3 3 0 TFA2 Winged helix domain 2 ApoO PF09769.9 EGR30004.1 - 0.015 15.2 3.3 0.065 13.2 0.5 2.4 1 1 1 2 2 2 0 Apolipoprotein O DUF885 PF05960.11 EGR30004.1 - 0.03 14.0 1.1 0.036 13.7 1.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Apolipoprotein PF01442.18 EGR30004.1 - 0.32 10.8 5.8 4.1 7.2 5.7 2.1 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain Fib_alpha PF08702.10 EGR30004.1 - 0.63 10.2 21.3 8.1 6.6 20.7 2.2 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Rotamase PF00639.21 EGR30004.1 - 0.67 11.0 5.6 4.3 8.4 0.9 2.4 2 0 0 2 2 2 0 PPIC-type PPIASE domain EAP30 PF04157.16 EGR30004.1 - 1 8.6 9.4 0.06 12.6 3.4 1.8 1 1 1 2 2 2 0 EAP30/Vps36 family DUF1664 PF07889.12 EGR30004.1 - 2 8.4 14.5 4.8 7.2 5.0 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Csm1_N PF18504.1 EGR30004.1 - 2.9 8.3 15.9 1.9 8.9 1.9 3.5 1 1 2 3 3 3 0 Csm1 N-terminal domain Jnk-SapK_ap_N PF09744.9 EGR30004.1 - 3.5 7.9 16.1 5.8 7.1 7.4 2.2 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 IZUMO PF15005.6 EGR30004.1 - 4.6 7.7 9.9 8.4 6.9 9.1 1.7 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated TPR_1 PF00515.28 EGR30006.1 - 0.00014 21.5 3.1 0.28 11.1 0.3 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGR30006.1 - 0.0002 21.2 8.2 0.11 12.7 0.1 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGR30006.1 - 0.0095 16.2 1.1 1.1 9.5 0.2 3.1 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGR30006.1 - 0.034 14.0 1.6 6.3 6.8 0.0 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat PIP5K PF01504.18 EGR30007.1 - 1.8e-53 181.5 15.3 1.8e-53 181.5 15.3 1.9 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase ATP_Ca_trans_C PF12424.8 EGR30007.1 - 0.096 13.2 0.1 0.27 11.7 0.1 1.7 1 0 0 1 1 1 0 Plasma membrane calcium transporter ATPase C terminal Senescence PF06911.12 EGR30008.1 - 0.074 13.4 0.4 0.12 12.7 0.4 1.3 1 0 0 1 1 1 0 Senescence-associated protein LRR_4 PF12799.7 EGR30008.1 - 8.3 7.0 9.2 1.6 9.3 1.6 3.7 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) UCR_hinge PF02320.16 EGR30010.1 - 7.7e-15 54.9 0.9 9.9e-15 54.5 0.9 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein polyprenyl_synt PF00348.17 EGR30011.1 - 3.8e-62 209.6 0.1 4.6e-62 209.4 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase DUF1725 PF08333.11 EGR30011.1 - 0.049 13.3 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) zf-CCCH_6 PF18585.1 EGR30011.1 - 0.11 12.4 1.1 5.2 7.0 0.1 2.6 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Asp2 PF16929.5 EGR30012.1 - 0.021 13.8 0.0 0.022 13.8 0.0 1.0 1 0 0 1 1 1 0 Accessory Sec system GspB-transporter Hydrolase_4 PF12146.8 EGR30012.1 - 0.028 13.7 0.0 0.03 13.6 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 ANAPC4_WD40 PF12894.7 EGR30016.1 - 1.3e-11 44.7 2.7 0.00032 20.9 0.0 5.5 3 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGR30016.1 - 1.4e-06 28.4 2.5 0.016 15.1 0.1 3.1 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Clathrin PF00637.20 EGR30016.1 - 2e-05 24.5 10.6 0.00013 21.9 0.5 3.9 2 1 2 4 4 4 2 Region in Clathrin and VPS WD40 PF00400.32 EGR30016.1 - 0.00028 21.6 3.6 1.3 10.0 0.2 4.8 4 0 0 4 4 4 1 WD domain, G-beta repeat TPR_7 PF13176.6 EGR30016.1 - 0.00092 19.1 8.4 0.071 13.2 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGR30016.1 - 0.0036 17.5 0.9 0.48 10.8 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGR30016.1 - 0.2 11.5 0.1 0.2 11.5 0.1 5.9 9 0 0 9 9 9 0 Tetratricopeptide repeat DZR PF12773.7 EGR30016.1 - 0.9 9.6 8.1 3.8 7.6 8.1 2.1 1 1 0 1 1 1 0 Double zinc ribbon TPR_6 PF13174.6 EGR30016.1 - 6 7.7 7.9 67 4.4 0.3 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGR30016.1 - 7.3 7.2 6.7 14 6.2 0.9 3.5 3 1 0 4 4 4 0 Tetratricopeptide repeat Fun_ATP-synt_8 PF05933.13 EGR30017.1 - 9.6 6.5 10.5 5.3 7.3 2.1 2.7 1 1 1 2 2 2 0 Fungal ATP synthase protein 8 (A6L) Pkinase PF00069.25 EGR30018.1 - 3.8e-11 42.8 1.2 3.8e-11 42.8 1.2 3.2 1 1 1 3 3 3 1 Protein kinase domain APH PF01636.23 EGR30018.1 - 0.013 15.5 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 EGR30018.1 - 4.6 6.4 18.7 0.31 10.3 10.2 2.4 1 1 1 2 2 2 0 Protein tyrosine kinase Spc7 PF08317.11 EGR30019.1 - 7.6e-05 21.7 13.5 7.6e-05 21.7 13.5 3.0 2 1 1 3 3 3 1 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 EGR30019.1 - 0.0003 21.4 11.2 0.0003 21.4 11.2 4.3 2 2 1 4 4 4 1 Clathrin-binding domain of Huntingtin-interacting protein 1 APG6_N PF17675.1 EGR30019.1 - 0.00072 20.1 12.2 0.00072 20.1 12.2 3.4 3 1 0 3 3 3 1 Apg6 coiled-coil region DivIC PF04977.15 EGR30019.1 - 0.0014 18.4 6.1 0.0014 18.4 6.1 4.7 5 1 0 5 5 5 1 Septum formation initiator DUF3450 PF11932.8 EGR30019.1 - 0.0057 16.0 8.8 0.0057 16.0 8.8 3.6 2 2 1 3 3 3 1 Protein of unknown function (DUF3450) Sipho_Gp157 PF05565.11 EGR30019.1 - 0.011 15.8 7.7 0.011 15.8 7.7 3.4 3 0 0 3 3 3 0 Siphovirus Gp157 DUF5082 PF16888.5 EGR30019.1 - 0.011 16.0 3.9 0.011 16.0 3.9 4.2 3 2 1 4 4 4 0 Domain of unknown function (DUF5082) DUF1664 PF07889.12 EGR30019.1 - 0.014 15.4 6.9 0.014 15.4 6.9 3.5 2 2 3 5 5 5 0 Protein of unknown function (DUF1664) Spc24 PF08286.11 EGR30019.1 - 0.019 15.2 6.4 0.019 15.2 6.4 4.5 3 2 1 4 4 4 0 Spc24 subunit of Ndc80 ETRAMP PF09716.10 EGR30019.1 - 0.43 10.7 11.1 0.061 13.4 3.2 3.1 3 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) UPF0242 PF06785.11 EGR30019.1 - 0.61 10.2 32.4 0.17 12.0 15.4 2.5 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus FlaC_arch PF05377.11 EGR30019.1 - 1.8 9.0 12.3 0.22 11.9 4.4 3.5 3 1 1 4 4 3 0 Flagella accessory protein C (FlaC) DUF2730 PF10805.8 EGR30019.1 - 4.9 7.3 9.4 1 9.5 3.3 2.9 2 2 0 2 2 2 0 Protein of unknown function (DUF2730) YvrJ PF12841.7 EGR30019.1 - 5 6.7 5.4 1.7 8.3 0.9 2.7 3 0 0 3 3 3 0 YvrJ protein family DUF948 PF06103.11 EGR30019.1 - 5.5 7.3 15.3 2.3e+02 2.1 3.3 4.9 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 EGR30019.1 - 5.8 7.4 26.5 0.76 10.3 2.1 4.8 1 1 2 4 4 4 0 Nucleopolyhedrovirus P10 protein ParA PF10609.9 EGR30021.1 - 0.12 11.9 0.1 0.14 11.6 0.1 1.1 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Sde2_N_Ubi PF13019.6 EGR30022.1 - 1.9e-20 73.3 0.0 6.5e-20 71.6 0.0 1.9 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain Ig_5 PF16681.5 EGR30022.1 - 0.023 15.1 1.3 0.023 15.1 1.3 3.2 2 0 0 2 2 2 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain DUF3450 PF11932.8 EGR30022.1 - 0.51 9.6 12.8 0.012 14.9 4.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Pkinase PF00069.25 EGR30023.1 - 1.7e-63 214.4 0.1 2.7e-63 213.8 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30023.1 - 4.1e-45 154.1 0.0 6.6e-45 153.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_6 PF13405.6 EGR30023.1 - 3.6e-08 32.7 6.6 0.00022 20.9 1.0 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EGR30023.1 - 1.5e-07 30.5 1.4 0.00059 19.2 0.4 3.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGR30023.1 - 5.5e-07 29.9 2.0 2.2e-06 28.0 0.5 2.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.6 EGR30023.1 - 2.6e-05 24.0 2.0 0.0004 20.2 0.1 3.1 3 0 0 3 3 3 1 EF-hand domain pair Pkinase_fungal PF17667.1 EGR30023.1 - 6.8e-05 21.8 0.0 0.00015 20.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase EF-hand_5 PF13202.6 EGR30023.1 - 0.00043 19.7 3.2 0.072 12.6 1.3 2.7 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 EGR30023.1 - 0.048 14.0 0.1 0.13 12.6 0.1 1.7 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region PHtD_u1 PF16645.5 EGR30023.1 - 0.15 12.5 0.0 0.35 11.3 0.0 1.6 1 0 0 1 1 1 0 Unstructured region on Pneumococcal histidine triad protein Peptidase_C12 PF01088.21 EGR30024.1 - 3.4e-56 190.3 1.9 4e-56 190.1 1.9 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 ASH PF15780.5 EGR30025.1 - 4.8e-18 65.2 0.5 0.0088 16.2 0.0 5.8 5 1 0 5 5 5 5 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 EGR30025.1 - 2.3e-15 56.4 24.7 3.6e-07 30.0 0.2 5.6 7 0 0 7 7 7 3 MSP (Major sperm protein) domain DUF5001 PF16392.5 EGR30025.1 - 0.0004 20.2 5.7 0.079 12.9 0.4 4.2 4 0 0 4 4 4 2 Ig-like domain IMPa_helical PF18642.1 EGR30026.1 - 0.071 13.5 0.4 0.13 12.7 0.4 1.4 1 0 0 1 1 1 0 Immunomodulating metalloprotease helical domain Pkinase PF00069.25 EGR30027.1 - 4.6e-42 144.2 1.6 7.3e-42 143.5 1.6 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30027.1 - 2.2e-17 63.2 0.9 3.4e-17 62.6 0.9 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR30027.1 - 7.9e-05 22.1 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR30027.1 - 0.026 13.3 0.0 0.045 12.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase PDR_CDR PF06422.12 EGR30029.1 - 4.1 7.4 9.4 2.3 8.2 7.2 1.6 1 1 1 2 2 2 0 CDR ABC transporter Dopey_N PF04118.14 EGR30030.1 - 8.1e-37 127.0 1.3 9.8e-37 126.7 1.3 1.0 1 0 0 1 1 1 1 Dopey, N-terminal ABC1 PF03109.16 EGR30031.1 - 3.5e-34 117.5 0.8 9.5e-34 116.1 0.0 2.0 2 0 0 2 2 2 1 ABC1 family DUF3400 PF11880.8 EGR30031.1 - 0.04 13.5 0.1 0.08 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3400) WD40 PF00400.32 EGR30032.1 - 2.2e-13 50.4 8.8 5.2e-05 23.9 0.2 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EGR30032.1 - 0.015 13.9 0.1 0.044 12.3 0.0 1.7 2 0 0 2 2 2 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 EGR30032.1 - 0.084 13.4 0.0 0.27 11.8 0.0 1.9 1 0 0 1 1 1 0 PQQ-like domain PHM7_cyt PF14703.6 EGR30034.1 - 9.2e-19 68.3 4.6 3.2e-18 66.6 4.6 2.0 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DctQ PF04290.12 EGR30034.1 - 0.00081 19.3 0.1 0.0045 16.9 0.0 2.2 2 0 0 2 2 2 1 Tripartite ATP-independent periplasmic transporters, DctQ component Kinesin PF00225.23 EGR30035.1 - 6.4e-101 337.6 11.2 7.9e-101 337.3 11.2 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR30035.1 - 6.1e-26 91.1 2.7 6.1e-26 91.1 2.7 1.9 2 0 0 2 2 2 1 Microtubule binding SUIM_assoc PF16619.5 EGR30035.1 - 0.17 12.0 3.5 0.49 10.5 3.5 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 VWA PF00092.28 EGR30036.1 - 1.2e-18 67.9 0.8 2.1e-18 67.2 0.8 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EGR30036.1 - 1.4e-18 67.3 0.0 1.9e-18 66.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGR30036.1 - 1.8e-18 67.1 0.1 3.4e-18 66.3 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EGR30036.1 - 2.5e-11 43.4 0.0 3.4e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 EGR30036.1 - 0.00019 21.6 0.1 0.0005 20.2 0.1 1.6 1 1 1 2 2 2 1 vWA found in TerF C terminus Sec23_trunk PF04811.15 EGR30036.1 - 0.001 18.7 0.1 0.0013 18.3 0.1 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Flavodoxin_3 PF12641.7 EGR30037.1 - 0.0085 15.8 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Flavodoxin domain Peptidase_M8 PF01457.16 EGR30038.1 - 1.3e-23 83.5 0.0 2.7e-23 82.4 0.0 1.4 1 1 0 1 1 1 1 Leishmanolysin Astacin PF01400.24 EGR30038.1 - 4e-08 33.1 0.0 5.4e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Astacin (Peptidase family M12A) Pkinase PF00069.25 EGR30039.1 - 4e-31 108.4 0.0 1.8e-29 102.9 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30039.1 - 5.8e-19 68.4 0.0 1.6e-18 66.9 0.0 1.6 1 1 1 2 2 2 1 Protein tyrosine kinase PhoD PF09423.10 EGR30039.1 - 2.3e-06 26.9 0.4 3.6e-05 22.9 0.4 2.1 1 1 0 1 1 1 1 PhoD-like phosphatase Pkinase_fungal PF17667.1 EGR30039.1 - 4e-05 22.6 0.0 6.3e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PX PF00787.24 EGR30040.1 - 3.7e-18 65.5 7.2 5.1e-18 65.1 0.1 3.2 3 1 0 3 3 3 1 PX domain PHM7_cyt PF14703.6 EGR30040.1 - 5.4 7.2 13.4 4.9 7.3 5.1 2.2 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF1090 PF06476.12 EGR30040.1 - 9.5 6.4 14.5 73 3.5 13.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1090) NUC173 PF08161.12 EGR30041.1 - 1.1e-15 57.8 1.3 1.1e-15 57.8 1.3 3.7 5 0 0 5 5 5 2 NUC173 domain UME PF08064.13 EGR30041.1 - 0.093 12.7 11.9 0.63 10.0 1.6 4.5 4 0 0 4 4 4 0 UME (NUC010) domain Dus PF01207.17 EGR30042.1 - 1e-48 166.1 0.0 3.6e-48 164.2 0.0 1.7 1 1 1 2 2 2 2 Dihydrouridine synthase (Dus) Crystall PF00030.19 EGR30043.1 - 8.2e-08 32.3 0.1 1.9e-07 31.2 0.1 1.6 1 0 0 1 1 1 1 Beta/Gamma crystallin IL4_i_Ig PF18258.1 EGR30043.1 - 0.028 14.6 0.9 0.077 13.2 0.3 2.1 2 0 0 2 2 2 0 Interleukin-4 inducing immunoglobulin-binding domain DEAD PF00270.29 EGR30044.1 - 6.4e-46 156.3 1.3 1.4e-45 155.2 1.3 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR30044.1 - 8.8e-24 84.0 4.4 3.9e-23 81.9 0.0 3.4 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGR30044.1 - 1.6e-16 60.3 0.1 3.4e-16 59.2 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGR30044.1 - 9.6e-06 25.7 0.2 9.6e-06 25.7 0.2 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Hira PF07569.11 EGR30044.1 - 0.0062 16.3 0.1 0.15 11.8 0.0 2.6 3 0 0 3 3 3 1 TUP1-like enhancer of split Helicase_RecD PF05127.14 EGR30044.1 - 0.0089 15.9 0.0 0.037 13.9 0.0 2.1 1 1 0 1 1 1 1 Helicase SecA_DEAD PF07517.14 EGR30044.1 - 0.018 14.3 0.3 0.046 13.0 0.0 1.8 2 0 0 2 2 2 0 SecA DEAD-like domain TPR_19 PF14559.6 EGR30045.1 - 1e-13 51.5 2.3 6.4e-06 26.6 0.0 5.1 3 2 1 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGR30045.1 - 2.9e-13 48.9 18.7 3.7e-05 23.6 0.0 7.9 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGR30045.1 - 2.6e-12 45.8 5.6 0.0013 18.7 0.0 6.5 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGR30045.1 - 7.4e-10 38.5 1.2 0.045 14.1 0.0 6.0 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR30045.1 - 5.7e-09 36.1 14.0 0.0087 16.3 0.8 5.1 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EGR30045.1 - 8.9e-09 35.5 1.8 0.0049 17.1 0.1 4.9 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGR30045.1 - 1.8e-08 33.8 15.6 0.0053 16.5 0.0 6.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGR30045.1 - 1e-06 29.2 0.0 0.00053 20.6 0.0 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGR30045.1 - 3e-05 24.5 0.0 1.3 10.1 0.0 5.5 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGR30045.1 - 0.005 17.0 0.0 0.017 15.3 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGR30045.1 - 0.016 15.1 0.3 4.3 7.3 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGR30045.1 - 0.016 15.8 1.1 7.6 7.4 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat PAS_8 PF13188.7 EGR30045.1 - 0.017 15.1 0.0 0.048 13.7 0.0 1.7 1 0 0 1 1 1 0 PAS domain TPR_7 PF13176.6 EGR30045.1 - 0.89 9.7 4.2 9.5 6.5 0.0 4.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGR30045.1 - 2.1 8.1 9.5 13 5.5 0.0 4.2 3 1 1 4 4 4 0 TPR repeat PAP_central PF04928.17 EGR30046.1 - 5e-46 156.7 0.4 6.4e-46 156.3 0.4 1.1 1 0 0 1 1 1 1 Poly(A) polymerase central domain NTP_transf_2 PF01909.23 EGR30046.1 - 0.00012 22.3 0.9 0.00029 21.1 0.1 2.2 2 1 0 2 2 2 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 EGR30046.1 - 0.00054 19.8 0.4 0.00086 19.1 0.4 1.4 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain DUF4269 PF14091.6 EGR30046.1 - 0.029 14.6 0.2 0.029 14.6 0.2 2.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4269) Polbeta PF18765.1 EGR30046.1 - 0.13 12.4 3.2 0.6 10.2 0.1 2.7 2 1 1 3 3 3 0 Polymerase beta, Nucleotidyltransferase TBP PF00352.21 EGR30047.1 - 1.7e-47 159.2 1.9 1.5e-24 85.7 0.3 2.0 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EGR30047.1 - 0.00015 21.8 2.9 0.15 12.2 1.2 2.9 2 1 0 2 2 2 2 Domain of unknown function (DUF3378) Xrn1_D3 PF18194.1 EGR30048.1 - 0.026 14.6 0.2 0.12 12.5 0.0 2.0 1 1 1 2 2 2 0 Exoribonuclease 1 Domain-3 Pkinase_Tyr PF07714.17 EGR30049.1 - 6.2e-61 205.9 0.0 9.8e-61 205.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGR30049.1 - 7.5e-59 199.2 0.1 1.4e-58 198.4 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 EGR30049.1 - 1.1e-10 41.5 31.7 1.4e-05 25.4 15.2 3.8 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGR30049.1 - 4.5e-09 35.9 30.4 9.8e-09 34.8 18.9 2.9 2 1 1 3 3 3 2 Leucine rich repeat RIO1 PF01163.22 EGR30049.1 - 4.8e-07 29.5 0.4 9.4e-07 28.6 0.4 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EGR30049.1 - 2.9e-06 26.8 0.1 1.1e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGR30049.1 - 3.2e-06 26.7 0.1 7.1e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGR30049.1 - 0.042 13.5 1.1 0.063 12.9 0.1 1.9 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGR30049.1 - 0.046 13.6 0.0 0.073 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family LRR_6 PF13516.6 EGR30049.1 - 4 7.7 16.6 6 7.2 2.2 3.8 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 EGR30049.1 - 5.6 7.9 32.0 1.4 9.8 0.4 5.9 6 0 0 6 6 5 0 Leucine Rich Repeat RRM_1 PF00076.22 EGR30050.1 - 5.9e-06 26.0 0.8 2.1e-05 24.2 0.0 2.4 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGR30050.1 - 0.0042 16.9 0.1 0.0042 16.9 0.1 2.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EGR30050.1 - 0.036 14.1 0.0 0.065 13.2 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif SpoU_sub_bind PF08032.12 EGR30050.1 - 0.7 10.2 0.0 0.7 10.2 0.0 3.8 2 1 2 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding Peptidase_M8 PF01457.16 EGR30052.1 - 7.1e-42 143.8 4.3 1.7e-37 129.4 0.0 2.2 1 1 1 2 2 2 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR30052.1 - 1.5e-05 24.9 4.2 4.2e-05 23.5 4.2 1.8 1 0 0 1 1 1 1 Tenascin EGF domain Zincin_1 PF06262.11 EGR30052.1 - 0.19 11.8 0.1 0.53 10.4 0.1 1.7 1 0 0 1 1 1 0 Zincin-like metallopeptidase Peptidase_M8 PF01457.16 EGR30053.1 - 7.5e-24 84.3 0.0 8.9e-24 84.1 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin Zincin_1 PF06262.11 EGR30053.1 - 0.18 11.9 0.2 0.32 11.1 0.2 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase Arrestin_N PF00339.29 EGR30054.1 - 8.9e-14 51.8 3.3 2.3e-13 50.4 1.4 2.3 2 0 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EGR30054.1 - 6.7e-12 46.0 1.7 2.6e-09 37.6 0.0 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain MG2 PF01835.19 EGR30054.1 - 0.035 14.6 0.0 1.4 9.4 0.0 2.8 2 0 0 2 2 2 0 MG2 domain Cyt-b5 PF00173.28 EGR30055.1 - 1.6e-05 25.0 0.0 3.3e-05 24.0 0.0 1.7 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MRG PF05712.13 EGR30055.1 - 0.0096 15.3 0.1 0.013 14.8 0.1 1.2 1 0 0 1 1 1 1 MRG Herpes_UL1 PF05259.11 EGR30055.1 - 0.087 12.9 0.0 0.22 11.6 0.0 1.6 1 1 0 1 1 1 0 Herpesvirus glycoprotein L Ribosomal_60s PF00428.19 EGR30058.1 - 1.7e-12 47.8 3.2 4.3e-12 46.4 3.2 1.7 1 0 0 1 1 1 1 60s Acidic ribosomal protein PCI PF01399.27 EGR30058.1 - 8.6e-11 42.3 1.4 8.6e-11 42.3 1.4 3.0 3 1 0 3 3 3 1 PCI domain NAD_binding_4 PF07993.12 EGR30058.1 - 0.064 12.4 0.1 0.11 11.6 0.1 1.4 1 0 0 1 1 1 0 Male sterility protein Alpha_TIF PF02232.15 EGR30058.1 - 0.092 11.8 2.1 5.5 6.0 0.3 2.2 2 0 0 2 2 2 0 Alpha trans-inducing protein (Alpha-TIF) SF3b10 PF07189.11 EGR30059.1 - 6.1e-34 116.0 0.1 9.9e-34 115.3 0.1 1.3 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Pkinase PF00069.25 EGR30060.1 - 3.4e-63 213.5 0.2 4.1e-63 213.2 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30060.1 - 1.7e-35 122.6 0.0 2.2e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR30060.1 - 0.0028 17.0 0.1 0.007 15.7 0.1 1.7 1 1 1 2 2 2 1 Kinase-like Kelch_5 PF13854.6 EGR30061.1 - 1.9e-33 113.9 9.7 3.8e-08 33.1 0.0 6.7 6 1 0 6 6 6 5 Kelch motif Kelch_4 PF13418.6 EGR30061.1 - 1.1e-30 105.4 11.1 1.1e-08 34.9 0.1 6.6 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EGR30061.1 - 6.4e-29 99.7 11.0 9.1e-10 38.6 0.0 7.8 7 2 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.25 EGR30061.1 - 1.3e-25 88.7 1.7 0.00084 18.9 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EGR30061.1 - 2.6e-25 87.4 17.4 5.1e-06 26.2 0.0 7.5 7 2 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 EGR30061.1 - 9.5e-21 73.3 15.2 1.5e-07 31.4 0.0 6.9 3 1 3 6 6 6 4 Kelch motif UPF0515 PF15135.6 EGR30061.1 - 0.15 11.4 2.7 0.21 10.9 2.7 1.2 1 0 0 1 1 1 0 Uncharacterised protein UPF0515 NOP5NT PF08156.13 EGR30063.1 - 0.22 11.9 5.5 0.13 12.6 2.3 2.1 2 0 0 2 2 2 0 NOP5NT (NUC127) domain Pkinase PF00069.25 EGR30065.1 - 7.9e-69 231.9 4.5 1.5e-68 231.0 4.5 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30065.1 - 1.8e-44 152.0 0.3 2.9e-44 151.3 0.3 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR30065.1 - 1.5e-06 27.3 1.0 2.8e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGR30065.1 - 4.5e-05 22.9 0.1 0.00019 20.9 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR30065.1 - 0.014 14.8 0.1 0.035 13.4 0.1 1.8 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR30065.1 - 0.16 11.8 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Autophagy_act_C PF03987.15 EGR30067.1 - 5.5e-18 65.3 0.3 9.4e-18 64.6 0.3 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 EGR30067.1 - 9.7e-16 57.0 0.2 1.7e-15 56.2 0.2 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal PaRep2b PF07775.11 EGR30067.1 - 0.094 11.2 0.0 0.37 9.2 0.0 1.7 1 1 1 2 2 2 0 PaRep2b protein PHD_2 PF13831.6 EGR30068.1 - 9.6e-15 53.9 2.6 9.6e-15 53.9 2.6 2.3 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 EGR30068.1 - 1.2e-11 44.3 9.1 1.4e-11 44.1 6.7 1.9 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 EGR30068.1 - 6.4e-05 22.8 4.5 6.4e-05 22.8 4.5 2.3 2 1 0 2 2 2 1 Prokaryotic RING finger family 1 C1_2 PF03107.16 EGR30068.1 - 0.011 16.0 10.1 0.12 12.7 5.8 2.3 2 0 0 2 2 2 0 C1 domain zf-PHD-like PF15446.6 EGR30068.1 - 0.012 15.2 3.6 0.018 14.7 3.6 1.5 1 1 0 1 1 1 0 PHD/FYVE-zinc-finger like domain C1_1 PF00130.22 EGR30068.1 - 0.032 14.1 4.8 0.032 14.1 4.8 2.4 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ephrin_rec_like PF07699.13 EGR30068.1 - 0.059 13.1 8.9 0.071 12.9 1.0 2.3 2 1 0 2 2 2 0 Putative ephrin-receptor like zf-RING_9 PF13901.6 EGR30068.1 - 0.11 12.5 6.7 0.036 14.0 4.4 1.4 1 1 0 1 1 1 0 Putative zinc-RING and/or ribbon zf-UDP PF14569.6 EGR30068.1 - 0.15 12.2 9.0 0.4 10.8 9.0 1.8 1 1 0 1 1 1 0 Zinc-binding RING-finger DUF2318 PF10080.9 EGR30068.1 - 0.22 11.6 7.5 0.084 13.0 3.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Siva PF05458.12 EGR30068.1 - 0.29 10.8 4.3 0.21 11.3 1.8 1.8 2 0 0 2 2 2 0 Cd27 binding protein (Siva) FYVE_2 PF02318.16 EGR30068.1 - 0.53 10.5 4.9 0.78 10.0 4.9 1.4 1 1 0 1 1 1 0 FYVE-type zinc finger RINGv PF12906.7 EGR30068.1 - 0.68 10.1 7.8 2.4 8.3 7.9 2.0 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.6 EGR30068.1 - 6.3 6.7 14.1 3.5 7.6 0.4 3.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) TTL PF03133.15 EGR30069.1 - 6.2e-37 127.3 6.9 3e-22 79.1 0.5 2.6 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR30069.1 - 3.4e-06 26.5 0.0 4e-05 23.0 0.0 2.3 1 1 1 2 2 2 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 EGR30069.1 - 0.035 13.6 0.1 0.11 12.1 0.0 1.9 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus ubiquitin PF00240.23 EGR30070.1 - 1.2e-33 114.7 0.4 2.3e-33 113.8 0.3 1.5 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_L40e PF01020.17 EGR30070.1 - 1.8e-27 95.0 12.0 2.7e-27 94.4 12.0 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 EGR30070.1 - 2.8e-15 55.9 0.9 4e-15 55.4 0.5 1.5 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGR30070.1 - 8.9e-05 22.9 0.1 0.00035 21.0 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EGR30070.1 - 0.0062 16.9 0.0 0.01 16.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGR30070.1 - 0.0085 16.2 0.1 0.015 15.4 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EGR30070.1 - 0.025 14.5 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 EGR30070.1 - 0.057 14.0 0.0 0.078 13.5 0.0 1.4 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EGR30070.1 - 0.064 13.3 1.0 6.7 6.8 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain PFO_beta_C PF12367.8 EGR30071.1 - 0.11 12.6 1.3 0.35 11.1 1.3 1.9 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal PMSR PF01625.21 EGR30071.1 - 0.71 10.0 5.5 0.23 11.6 1.9 2.0 2 0 0 2 2 2 0 Peptide methionine sulfoxide reductase SNARE PF05739.19 EGR30072.1 - 1e-11 44.6 0.4 2.8e-11 43.2 0.4 1.8 1 0 0 1 1 1 1 SNARE domain TACC_C PF05010.14 EGR30072.1 - 0.035 13.9 26.2 0.63 9.8 14.3 3.1 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Dak2 PF02734.17 EGR30072.1 - 0.23 11.3 1.3 1.3 8.9 0.0 2.4 1 1 1 2 2 2 0 DAK2 domain MAD PF05557.13 EGR30072.1 - 0.54 8.6 30.2 0.071 11.5 26.5 1.3 2 0 0 2 2 2 0 Mitotic checkpoint protein YjcZ PF13990.6 EGR30072.1 - 0.65 9.3 9.2 0.059 12.7 3.2 2.0 1 1 0 1 1 1 0 YjcZ-like protein DUF2203 PF09969.9 EGR30072.1 - 1.1 10.0 18.6 2.1 9.1 1.2 3.5 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Peptidase_C10 PF01640.17 EGR30072.1 - 1.3 9.3 7.5 0.14 12.4 1.2 2.2 1 1 1 2 2 2 0 Peptidase C10 family TraB PF01963.17 EGR30072.1 - 1.4 8.8 14.9 2.4 8.0 14.2 1.7 1 1 0 1 1 1 0 TraB family SseC PF04888.12 EGR30072.1 - 4.9 6.6 9.1 13 5.3 9.0 1.7 1 1 0 1 1 1 0 Secretion system effector C (SseC) like family ZYG-11_interact PF05884.12 EGR30072.1 - 5.2 6.4 12.6 0.27 10.6 2.9 2.3 1 1 1 2 2 2 0 Interactor of ZYG-11 Syntaxin PF00804.25 EGR30072.1 - 6.6 6.4 24.9 0.84 9.3 1.2 2.7 2 1 1 3 3 3 0 Syntaxin WD40 PF00400.32 EGR30073.1 - 1.1e-17 64.0 3.5 0.0062 17.4 0.1 8.5 9 0 0 9 9 9 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR30073.1 - 9.6e-06 25.8 0.2 0.43 10.9 0.0 4.1 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.6 EGR30073.1 - 0.0065 16.9 3.9 0.08 13.4 0.1 3.4 3 0 0 3 3 3 1 EF-hand domain pair zf-MYST PF17772.1 EGR30073.1 - 0.073 12.7 0.0 9.4 5.9 0.0 3.2 2 0 0 2 2 2 0 MYST family zinc finger domain EF-hand_1 PF00036.32 EGR30073.1 - 0.082 12.5 0.8 0.37 10.4 0.4 2.4 2 0 0 2 2 2 0 EF hand Na_H_Exchanger PF00999.21 EGR30074.1 - 1.3e-53 182.2 14.6 1.4e-53 182.0 14.6 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Hemocyanin_N PF03722.14 EGR30074.1 - 0.029 14.9 1.7 7.4 7.1 0.8 2.5 2 0 0 2 2 2 0 Hemocyanin, all-alpha domain TRAM1 PF08390.11 EGR30074.1 - 0.17 11.5 2.0 3.4 7.4 0.1 2.7 2 0 0 2 2 2 0 TRAM1-like protein DUF1218 PF06749.12 EGR30074.1 - 0.36 11.4 3.6 0.97 10.0 0.0 3.2 3 2 1 4 4 4 0 Protein of unknown function (DUF1218) DUF4059 PF13268.6 EGR30074.1 - 1.2 9.6 0.0 1.2 9.6 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF4059) DUF202 PF02656.15 EGR30074.1 - 5 7.6 10.7 0.96 9.9 0.1 3.8 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Pkinase PF00069.25 EGR30075.1 - 5.5e-64 216.1 2.9 7.4e-64 215.6 2.9 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30075.1 - 5.1e-45 153.8 0.8 8.8e-45 153.0 0.8 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR30075.1 - 1.5e-06 27.7 0.1 1.3e-05 24.6 0.0 2.2 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR30075.1 - 0.00028 19.8 0.0 0.0007 18.5 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR30075.1 - 0.004 16.5 0.0 0.01 15.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family BST2 PF16716.5 EGR30075.1 - 0.069 13.7 10.4 0.78 10.4 0.4 2.8 3 1 0 3 3 3 0 Bone marrow stromal antigen 2 APH PF01636.23 EGR30075.1 - 0.1 12.5 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2207 PF09972.9 EGR30076.1 - 0.77 8.5 16.7 0.91 8.2 16.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF87 PF01935.17 EGR30076.1 - 3.5 7.6 12.4 4.7 7.2 12.4 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain HSF_DNA-bind PF00447.17 EGR30077.1 - 1.7e-26 92.6 6.0 4.5e-26 91.3 6.0 1.9 1 1 0 1 1 1 1 HSF-type DNA-binding APG6_N PF17675.1 EGR30077.1 - 0.068 13.7 5.7 0.031 14.8 3.5 1.6 2 0 0 2 2 2 0 Apg6 coiled-coil region PAH PF02671.21 EGR30077.1 - 0.072 13.2 10.1 63 3.8 10.1 2.6 1 1 0 1 1 1 0 Paired amphipathic helix repeat JIP_LZII PF16471.5 EGR30077.1 - 0.078 13.2 3.0 0.13 12.5 1.8 2.0 1 1 1 2 2 2 0 JNK-interacting protein leucine zipper II Peptidase_S11 PF00768.20 EGR30078.1 - 1e-21 77.5 1.0 3.7e-20 72.4 0.5 2.1 2 0 0 2 2 2 2 D-alanyl-D-alanine carboxypeptidase Copine PF07002.16 EGR30079.1 - 3e-68 229.5 0.0 4.7e-68 228.9 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 EGR30079.1 - 8.1e-17 61.4 1.1 1.3e-08 35.0 0.1 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EGR30079.1 - 8.6e-06 26.0 0.0 2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus AlphaC_N PF08829.10 EGR30079.1 - 0.06 13.4 0.4 1.1 9.3 0.1 2.6 2 0 0 2 2 2 0 Alpha C protein N terminal Ldh_1_C PF02866.18 EGR30080.1 - 6.1e-33 114.1 0.0 9.6e-33 113.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EGR30080.1 - 2.6e-31 108.6 0.4 8.3e-31 107.0 0.0 1.9 2 0 0 2 2 2 1 lactate/malate dehydrogenase, NAD binding domain Cystatin PF00031.21 EGR30081.1 - 3.4e-06 27.2 0.3 4.1e-06 27.0 0.3 1.1 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 EGR30081.1 - 0.033 14.5 0.1 0.042 14.2 0.1 1.3 1 0 0 1 1 1 0 Aspartic acid proteinase inhibitor TTL PF03133.15 EGR30082.1 - 5.1e-54 183.4 15.9 2.3e-53 181.2 15.9 1.9 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR30082.1 - 4.8e-07 29.3 1.8 0.0021 17.3 0.0 2.7 3 0 0 3 3 3 2 YheC/D like ATP-grasp Pkinase PF00069.25 EGR30083.1 - 8.6e-56 189.2 0.1 2.3e-55 187.8 0.1 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30083.1 - 1.2e-35 123.1 0.0 3.5e-35 121.5 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR30083.1 - 7.3e-06 25.0 0.0 1.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR30083.1 - 0.088 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Complex1_LYR_2 PF13233.6 EGR30083.1 - 0.61 10.9 2.6 17 6.2 0.1 3.1 2 0 0 2 2 2 0 Complex1_LYR-like Peptidase_S49 PF01343.18 EGR30084.1 - 1e-06 28.8 0.1 2.4e-06 27.6 0.1 1.5 1 1 0 1 1 1 1 Peptidase family S49 FANCF PF11107.8 EGR30084.1 - 0.0094 15.2 0.5 0.012 14.9 0.5 1.1 1 0 0 1 1 1 1 Fanconi anemia group F protein (FANCF) CLP_protease PF00574.23 EGR30084.1 - 0.025 14.4 0.1 0.11 12.3 0.0 1.9 2 0 0 2 2 2 0 Clp protease Tweety PF04906.13 EGR30084.1 - 0.028 13.1 2.3 0.039 12.6 2.1 1.3 1 1 0 1 1 1 0 Tweety Peptidase_C92 PF05708.12 EGR30084.1 - 0.047 13.8 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family Complex1_49kDa PF00346.19 EGR30084.1 - 0.1 11.7 0.0 0.19 10.8 0.0 1.4 1 1 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit ThiF PF00899.21 EGR30085.1 - 6.7e-11 42.0 0.0 1.3e-09 37.8 0.0 2.1 1 1 0 1 1 1 1 ThiF family Kinesin PF00225.23 EGR30086.1 - 3.6e-96 322.0 2.6 3.6e-96 322.0 2.6 2.3 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGR30086.1 - 4.7e-27 94.8 2.2 4.7e-27 94.8 2.2 2.8 2 1 1 3 3 3 1 Microtubule binding zf-RING_2 PF13639.6 EGR30087.1 - 1.8e-07 31.4 8.8 5.6e-07 29.8 8.8 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGR30087.1 - 0.0001 22.5 8.3 0.00036 20.8 8.3 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain FANCL_C PF11793.8 EGR30087.1 - 0.00011 22.3 6.5 0.00011 22.3 6.5 2.5 2 0 0 2 2 1 1 FANCL C-terminal domain zf-ANAPC11 PF12861.7 EGR30087.1 - 0.00016 21.7 1.8 0.00043 20.3 1.8 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGR30087.1 - 0.0053 16.4 5.2 0.015 14.9 5.2 1.7 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 EGR30087.1 - 0.0062 16.3 8.9 0.0062 16.3 8.9 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EGR30087.1 - 0.026 14.6 7.8 0.064 13.4 7.8 1.7 1 0 0 1 1 1 0 RING-variant domain Zf_RING PF16744.5 EGR30087.1 - 0.026 14.6 3.1 0.077 13.1 3.1 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger zf-RING-like PF08746.11 EGR30087.1 - 0.088 13.1 7.9 0.21 11.9 7.9 1.7 1 0 0 1 1 1 0 RING-like domain zf-C3HC4 PF00097.25 EGR30087.1 - 0.097 12.6 16.2 0.0095 15.8 10.7 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 EGR30087.1 - 0.16 11.9 5.6 0.21 11.5 4.5 1.8 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SIR2 PF02146.17 EGR30087.1 - 0.43 10.5 7.9 2.2 8.2 1.3 3.9 2 0 0 2 2 2 0 Sir2 family PHD PF00628.29 EGR30087.1 - 0.43 10.5 8.0 0.96 9.4 8.0 1.7 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 EGR30087.1 - 4.3 7.2 6.8 11 6.0 6.8 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 EGR30087.1 - 6.1 6.7 6.5 2.7 7.8 2.6 2.5 2 0 0 2 2 2 0 RING-like zinc finger Clathrin_lg_ch PF01086.17 EGR30088.1 - 2.1e-06 28.0 0.5 2.2e-06 27.9 0.5 1.0 1 0 0 1 1 1 1 Clathrin light chain Ribosomal_S21 PF01165.20 EGR30088.1 - 0.13 12.0 0.7 0.7 9.7 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S21 HTH_3 PF01381.22 EGR30089.1 - 1.1e-13 51.0 0.4 4e-13 49.2 0.1 2.1 2 1 0 2 2 2 1 Helix-turn-helix HTH_31 PF13560.6 EGR30089.1 - 2e-07 31.3 0.0 3.4e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_19 PF12844.7 EGR30089.1 - 1.4e-06 28.2 0.1 4.8e-06 26.5 0.0 1.8 1 1 1 2 2 2 1 Helix-turn-helix domain Peptidase_M6 PF05547.11 EGR30089.1 - 0.00028 19.4 0.8 0.00032 19.2 0.8 1.0 1 0 0 1 1 1 1 Immune inhibitor A peptidase M6 MBF1 PF08523.10 EGR30089.1 - 0.00069 20.0 3.3 0.0016 18.9 3.3 1.6 1 0 0 1 1 1 1 Multiprotein bridging factor 1 Methyltrn_RNA_3 PF02598.17 EGR30089.1 - 0.0011 18.6 0.7 0.0013 18.3 0.7 1.1 1 0 0 1 1 1 1 Putative RNA methyltransferase HTH_25 PF13413.6 EGR30089.1 - 0.055 13.3 0.1 0.2 11.5 0.0 2.1 2 1 0 2 2 2 0 Helix-turn-helix domain Forkhead PF00250.18 EGR30090.1 - 0.0075 16.5 0.6 0.017 15.4 0.0 1.9 2 1 1 3 3 3 1 Forkhead domain VraX PF17412.2 EGR30090.1 - 0.021 14.4 0.1 0.05 13.3 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function Clathrin-link PF09268.10 EGR30090.1 - 0.031 13.6 0.0 0.058 12.8 0.0 1.5 1 0 0 1 1 1 0 Clathrin, heavy-chain linker CompInhib_SCIN PF11546.8 EGR30090.1 - 0.074 13.1 1.0 0.24 11.5 0.1 2.0 1 1 1 2 2 2 0 Staphylococcal complement inhibitor SCIN HIT PF01230.23 EGR30091.1 - 1.7e-25 89.6 0.0 2e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGR30091.1 - 6e-19 68.6 0.0 6.8e-19 68.4 0.0 1.0 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Pkinase PF00069.25 EGR30092.1 - 1.5e-65 221.2 0.9 1.5e-65 221.2 0.9 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30092.1 - 2.1e-34 119.0 0.2 2.1e-34 119.0 0.2 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EGR30092.1 - 0.0093 15.9 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family KH_1 PF00013.29 EGR30092.1 - 0.2 11.5 3.9 0.18 11.7 0.8 2.6 2 1 0 2 2 2 0 KH domain DUF2309 PF10070.9 EGR30092.1 - 0.22 9.8 2.1 0.32 9.3 2.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) DEAD_2 PF06733.15 EGR30093.1 - 5.4e-44 149.9 6.6 5.4e-44 149.9 6.6 3.0 2 1 1 3 3 3 1 DEAD_2 Helicase_C_2 PF13307.6 EGR30093.1 - 4.2e-25 88.9 0.1 4.2e-25 88.9 0.1 2.7 4 0 0 4 4 4 1 Helicase C-terminal domain DEAD PF00270.29 EGR30093.1 - 4.1e-09 36.5 0.3 5.9e-07 29.4 0.3 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGR30093.1 - 1.2e-07 31.9 2.4 1.2e-07 31.9 2.4 3.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA PF00004.29 EGR30093.1 - 0.0052 17.2 0.7 11 6.4 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Pox_H7 PF04787.12 EGR30093.1 - 0.015 15.8 0.7 0.015 15.8 0.7 2.1 2 0 0 2 2 2 0 Late protein H7 AAA_11 PF13086.6 EGR30093.1 - 0.14 11.9 8.6 0.84 9.4 8.6 2.3 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 EGR30094.1 - 1.9e-46 158.6 4.3 2.4e-46 158.2 4.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30094.1 - 3.7e-33 114.9 1.2 4.3e-33 114.7 1.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR30094.1 - 6.2e-08 31.8 0.0 9.1e-08 31.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EGR30094.1 - 0.0014 18.3 0.2 0.0026 17.4 0.2 1.4 1 0 0 1 1 1 1 RIO1 family YrbL-PhoP_reg PF10707.9 EGR30094.1 - 0.011 15.3 0.4 0.022 14.3 0.4 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 EGR30094.1 - 0.011 15.6 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Spuma_A9PTase PF03539.14 EGR30094.1 - 0.019 15.1 5.8 0.48 10.6 1.9 2.3 2 0 0 2 2 2 0 Spumavirus aspartic protease (A9) Porin_3 PF01459.22 EGR30095.1 - 1.4e-07 31.3 2.3 1.4e-07 31.3 2.3 2.0 2 1 0 2 2 2 1 Eukaryotic porin DUF2722 PF10846.8 EGR30095.1 - 0.014 14.4 0.2 0.019 13.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) GPI-anchored PF10342.9 EGR30095.1 - 0.92 10.3 7.8 19 6.1 1.0 3.0 2 1 0 2 2 2 0 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family GAF PF01590.26 EGR30096.1 - 4e-08 34.0 0.0 1.1e-05 26.0 0.0 2.2 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 EGR30096.1 - 0.00025 21.4 0.0 0.0034 17.7 0.0 2.0 2 0 0 2 2 2 1 GAF domain bHLH-MYC_N PF14215.6 EGR30096.1 - 0.026 14.8 0.0 0.74 10.1 0.0 2.3 1 1 1 2 2 2 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal TTRAP PF14203.6 EGR30096.1 - 0.04 13.9 1.1 0.76 9.8 0.0 2.7 2 1 0 2 2 2 0 Putative tranposon-transfer assisting protein WD40 PF00400.32 EGR30097.1 - 5.4e-28 96.7 1.5 1.5e-05 25.7 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR30097.1 - 1.2e-17 64.0 2.9 9.8e-08 32.2 0.2 4.2 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGR30097.1 - 4.4e-07 30.0 1.7 0.004 17.0 0.1 3.1 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGR30097.1 - 0.00072 19.0 0.0 0.0093 15.3 0.0 2.3 2 1 1 3 3 3 1 WD40-like domain TFIIIC_delta PF12657.7 EGR30097.1 - 0.0019 18.1 5.1 0.027 14.4 5.2 2.5 1 1 0 1 1 1 1 Transcription factor IIIC subunit delta N-term Ge1_WD40 PF16529.5 EGR30097.1 - 0.0047 15.9 0.1 0.027 13.4 0.0 2.3 1 1 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4378 PF14309.6 EGR30098.1 - 2.4e-08 34.5 3.9 3.6e-08 34.0 3.9 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4378) Ephrin_rec_like PF07699.13 EGR30099.1 - 5.9e-05 22.8 3.8 0.0001 22.0 3.8 1.4 1 0 0 1 1 1 1 Putative ephrin-receptor like NCD3G PF07562.14 EGR30099.1 - 0.011 15.7 2.5 1.4 8.9 0.1 2.1 1 1 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR NiFe_hyd_SSU_C PF14720.6 EGR30099.1 - 0.14 12.6 3.6 0.12 12.8 2.8 1.3 1 1 0 1 1 1 0 NiFe/NiFeSe hydrogenase small subunit C-terminal Ribosomal_S7 PF00177.21 EGR30101.1 - 9.9e-35 119.4 0.5 1.3e-34 119.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e FAM25 PF15825.5 EGR30101.1 - 0.029 14.7 0.0 8 6.9 0.0 2.4 2 0 0 2 2 2 0 FAM25 family LAGLIDADG_WhiA PF14527.6 EGR30102.1 - 0.084 13.0 0.5 0.18 11.9 0.2 1.6 2 0 0 2 2 2 0 WhiA LAGLIDADG-like domain Myosin_head PF00063.21 EGR30103.1 - 9.6e-186 618.9 25.9 1.3e-185 618.5 25.9 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) AAA_22 PF13401.6 EGR30103.1 - 0.0065 16.8 0.2 0.08 13.2 0.0 2.7 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGR30103.1 - 0.044 14.2 0.6 5.7 7.4 0.1 3.1 2 0 0 2 2 2 0 RNA helicase WD40 PF00400.32 EGR30104.1 - 2.9e-08 34.2 0.0 0.014 16.3 0.0 2.8 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR30104.1 - 1.4e-07 31.7 0.0 0.0048 17.2 0.0 2.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain CPSF_A PF03178.15 EGR30104.1 - 0.00074 18.9 0.0 0.3 10.3 0.0 2.1 2 0 0 2 2 2 2 CPSF A subunit region Ge1_WD40 PF16529.5 EGR30104.1 - 0.0022 17.0 0.1 1.4 7.8 0.1 2.3 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein RNA_pol_Rpb2_4 PF04566.13 EGR30104.1 - 0.086 13.2 0.0 0.27 11.6 0.0 1.9 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 UCH PF00443.29 EGR30106.1 - 6.5e-53 179.9 8.0 2e-52 178.2 8.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR30106.1 - 3.9e-10 39.8 15.5 3.2e-06 27.0 6.5 2.1 1 1 1 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EGR30106.1 - 0.012 15.3 0.1 0.24 11.1 0.1 2.7 2 0 0 2 2 2 0 Ubiquitin family DUF3161 PF11362.8 EGR30106.1 - 0.057 13.4 2.2 0.53 10.3 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3161) zf-ribbon_3 PF13248.6 EGR30106.1 - 0.1 12.0 1.3 1.3 8.5 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DHHA1 PF02272.19 EGR30106.1 - 0.78 10.2 2.4 3.8 7.9 0.0 3.0 3 0 0 3 3 3 0 DHHA1 domain Curlin_rpt PF07012.12 EGR30106.1 - 0.94 9.5 5.2 2.1 8.4 0.9 2.7 2 0 0 2 2 2 0 Curlin associated repeat PHD PF00628.29 EGR30106.1 - 3.7 7.5 5.4 0.84 9.6 1.7 1.8 2 0 0 2 2 2 0 PHD-finger WD40 PF00400.32 EGR30107.1 - 4.8e-09 36.7 7.3 0.0012 19.6 0.5 3.9 3 1 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR30107.1 - 0.012 15.8 0.4 1.7 9.0 0.1 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Hexapep PF00132.24 EGR30110.1 - 1.1e-10 40.7 2.9 2.2e-06 27.2 0.1 4.0 3 1 2 5 5 5 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGR30110.1 - 7.6e-08 32.0 4.2 7.9e-08 31.9 0.2 2.6 2 1 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EGR30110.1 - 3.6e-05 22.9 0.4 0.022 13.7 0.1 2.1 1 1 1 2 2 2 2 L-fucokinase zf-HC2 PF13490.6 EGR30110.1 - 0.034 14.4 0.0 0.077 13.3 0.0 1.7 1 0 0 1 1 1 0 Putative zinc-finger FtsX_ECD PF18075.1 EGR30110.1 - 0.16 12.6 1.7 20 5.9 0.1 2.5 2 0 0 2 2 2 0 FtsX extracellular domain Mod_r PF07200.13 EGR30110.1 - 2.5 8.2 7.3 0.86 9.7 2.2 2.2 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Aminotran_3 PF00202.21 EGR30112.1 - 1.3e-112 376.5 0.0 1.7e-112 376.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EGR30112.1 - 1.5e-06 27.6 0.0 2.5e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II PerB PF06590.11 EGR30112.1 - 0.16 12.5 0.0 0.31 11.6 0.0 1.4 1 0 0 1 1 1 0 PerB protein Pecanex_C PF05041.15 EGR30113.1 - 1.6e-17 63.9 0.9 2.6e-17 63.1 0.9 1.4 1 0 0 1 1 1 1 Pecanex protein (C-terminus) CbtA_toxin PF06755.12 EGR30113.1 - 0.1 12.6 0.0 0.41 10.7 0.0 1.9 2 0 0 2 2 2 0 CbtA_toxin of type IV toxin-antitoxin system Palm_thioest PF02089.15 EGR30113.1 - 0.95 9.2 5.1 3.3 7.5 4.4 2.1 1 1 0 1 1 1 0 Palmitoyl protein thioesterase Abhydrolase_3 PF07859.13 EGR30114.1 - 1.5e-44 152.4 0.0 2.1e-44 151.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGR30114.1 - 8e-13 48.0 3.1 1.1e-12 47.5 3.1 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EGR30114.1 - 0.0068 15.9 0.0 4.8 6.6 0.0 2.5 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.28 EGR30114.1 - 0.052 12.4 0.2 0.17 10.7 0.2 1.8 1 1 0 1 1 1 0 Carboxylesterase family Peptidase_C1 PF00112.23 EGR30116.1 - 1.4e-50 172.4 5.0 1.4e-50 172.4 5.0 2.6 2 1 1 3 3 3 1 Papain family cysteine protease CathepsinC_exc PF08773.11 EGR30116.1 - 2e-33 115.2 3.4 2e-33 115.2 3.4 2.3 2 1 1 3 3 3 1 Cathepsin C exclusion domain Peptidase_C1_2 PF03051.15 EGR30116.1 - 0.00014 20.7 14.2 0.00023 20.1 0.5 2.8 3 0 0 3 3 3 2 Peptidase C1-like family Propeptide_C1 PF08127.13 EGR30116.1 - 0.016 15.1 1.3 0.033 14.1 0.2 2.1 2 0 0 2 2 2 0 Peptidase family C1 propeptide Pkinase PF00069.25 EGR30117.1 - 2.6e-62 210.6 3.1 2.6e-62 210.6 3.1 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30117.1 - 3.9e-32 111.6 0.5 6.8e-32 110.8 0.5 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR30117.1 - 0.0014 18.0 0.5 0.0031 16.9 0.5 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Yip1 PF04893.17 EGR30118.1 - 9.1e-13 48.3 14.9 1.3e-12 47.8 14.7 1.4 1 1 0 1 1 1 1 Yip1 domain ASFV_J13L PF05568.11 EGR30118.1 - 3.5 7.4 5.0 5.1 6.8 5.0 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein zf-C2H2 PF00096.26 EGR30119.1 - 0.0032 17.8 0.2 0.007 16.8 0.2 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type H-kinase_dim PF02895.14 EGR30119.1 - 0.014 15.7 1.0 0.014 15.7 1.0 2.5 3 1 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain zf-C2H2_4 PF13894.6 EGR30119.1 - 0.018 15.8 1.1 0.03 15.2 0.3 1.8 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGR30119.1 - 1.1 9.9 4.0 4.4 7.9 0.4 2.8 2 1 0 2 2 2 0 Zinc-finger double domain Pkinase PF00069.25 EGR30120.1 - 1.7e-69 234.2 4.9 1.7e-69 234.2 4.9 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30120.1 - 2.8e-39 135.0 0.6 5.2e-39 134.1 0.6 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR30120.1 - 2.7e-12 46.6 0.5 2.7e-12 46.6 0.5 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGR30120.1 - 1.6e-05 24.9 0.1 3.1e-05 24.0 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR30120.1 - 0.00053 19.4 0.8 0.0011 18.4 0.8 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PP2C PF00481.21 EGR30121.1 - 2.3e-28 99.5 0.0 2.8e-28 99.3 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGR30121.1 - 0.004 16.8 0.0 0.0052 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGR30121.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.3 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) Pkinase PF00069.25 EGR30122.1 - 4.2e-51 173.8 1.4 5e-51 173.6 1.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30122.1 - 3.2e-31 108.6 0.1 3.6e-31 108.4 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR30122.1 - 2.4e-05 23.5 0.2 3e-05 23.1 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGR30122.1 - 0.00057 19.3 0.0 0.00074 18.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR30122.1 - 0.0046 15.8 0.0 0.0064 15.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase DUF2816 PF10992.8 EGR30123.1 - 3.7e-15 55.6 20.5 3.7e-15 55.6 20.5 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF2816) Gln-synt_C PF00120.24 EGR30124.1 - 1.9e-16 60.0 0.0 4.5e-12 45.6 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Bax1-I PF01027.20 EGR30125.1 - 3.1e-13 50.0 30.3 3.5e-13 49.9 30.3 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Isochorismatase PF00857.20 EGR30126.1 - 9.7e-30 104.0 0.0 1.5e-29 103.4 0.0 1.3 1 1 0 1 1 1 1 Isochorismatase family YfmQ PF10787.9 EGR30126.1 - 0.034 13.9 0.9 0.2 11.4 0.1 2.2 2 1 0 2 2 2 0 Uncharacterised protein from bacillus cereus group PGK PF00162.19 EGR30128.1 - 2.3e-140 467.8 0.0 2.9e-140 467.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase Peptidase_S15 PF02129.18 EGR30129.1 - 0.023 14.3 0.0 0.027 14.1 0.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 EGR30129.1 - 0.18 11.0 0.0 0.24 10.6 0.0 1.1 1 0 0 1 1 1 0 Serine aminopeptidase, S33 WD40 PF00400.32 EGR30130.1 - 2.4e-13 50.3 3.0 0.00036 21.3 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat WD40_alt PF14077.6 EGR30130.1 - 0.088 12.7 4.3 0.41 10.6 4.3 2.2 1 0 0 1 1 1 0 Alternative WD40 repeat motif Metal_resist PF13801.6 EGR30130.1 - 2.3 8.4 5.3 1.6 8.9 2.0 2.2 2 0 0 2 2 2 0 Heavy-metal resistance NAD_binding_4 PF07993.12 EGR30131.1 - 2.5e-43 148.1 0.0 4.6e-43 147.2 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.21 EGR30131.1 - 1.4e-21 76.6 0.1 3.6e-21 75.2 0.1 1.7 1 0 0 1 1 1 1 Acyltransferase Sterile PF03015.19 EGR30131.1 - 1.1e-12 47.9 5.4 1.2e-12 47.9 2.9 2.5 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 EGR30131.1 - 7.5e-07 28.8 0.0 2.9e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1829 PF08862.10 EGR30131.1 - 0.44 11.1 5.1 1.5 9.3 3.7 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF1829 OB_NTP_bind PF07717.16 EGR30133.1 - 4.6e-25 87.8 0.3 1.4e-24 86.3 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EGR30133.1 - 1.6e-23 83.0 0.0 1.6e-23 83.0 0.0 3.0 2 1 0 2 2 2 1 Helicase associated domain (HA2) S1 PF00575.23 EGR30133.1 - 3.1e-16 59.5 3.9 4.1e-16 59.1 0.4 2.5 2 0 0 2 2 2 1 S1 RNA binding domain Helicase_C PF00271.31 EGR30133.1 - 8.7e-13 48.6 0.0 5.8e-12 45.9 0.0 2.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGR30133.1 - 2e-06 27.7 0.4 6.5e-06 26.0 0.4 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGR30133.1 - 3.1e-06 27.5 1.6 7.3e-06 26.3 0.1 2.4 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 EGR30133.1 - 5.2e-06 25.7 1.3 1.3e-05 24.4 1.3 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_30 PF13604.6 EGR30133.1 - 0.002 17.9 0.0 0.0047 16.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGR30133.1 - 0.002 18.4 0.1 0.0058 17.0 0.1 1.7 1 0 0 1 1 1 1 AAA domain Pkinase PF00069.25 EGR30134.1 - 7.8e-66 222.1 0.4 7.8e-66 222.1 0.4 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30134.1 - 1.2e-44 152.6 0.1 2.7e-44 151.4 0.1 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR30134.1 - 0.00019 20.9 0.1 0.00019 20.9 0.1 2.2 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR30134.1 - 0.0017 17.2 0.2 0.0048 15.7 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase HTH_54 PF18607.1 EGR30134.1 - 0.0076 16.3 1.2 0.0076 16.3 1.2 2.0 2 0 0 2 2 2 1 ParA helix turn helix domain APH PF01636.23 EGR30134.1 - 0.089 12.7 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-RING_9 PF13901.6 EGR30134.1 - 0.97 9.4 6.6 0.63 10.0 0.3 2.7 3 0 0 3 3 3 0 Putative zinc-RING and/or ribbon Carbam_trans_C PF16861.5 EGR30135.1 - 0.039 13.5 0.2 0.1 12.2 0.2 1.6 1 0 0 1 1 1 0 Carbamoyltransferase C-terminus YtxH PF12732.7 EGR30135.1 - 8.7 7.0 18.4 5.6e+02 1.2 0.0 7.2 3 2 0 3 3 3 0 YtxH-like protein ADIP PF11559.8 EGR30136.1 - 1.6e-21 77.0 169.3 0.0024 18.0 15.2 12.2 1 1 12 13 13 13 8 Afadin- and alpha -actinin-Binding AAA_13 PF13166.6 EGR30136.1 - 9.1e-19 67.6 134.0 2.7e-06 26.3 26.9 6.3 1 1 6 7 7 7 6 AAA domain Filament PF00038.21 EGR30136.1 - 5.8e-18 65.5 164.3 0.00029 20.5 15.4 8.7 1 1 6 7 7 7 7 Intermediate filament protein Spc7 PF08317.11 EGR30136.1 - 1.9e-17 63.1 161.7 6.5e-06 25.2 26.3 8.3 1 1 7 8 8 8 6 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 EGR30136.1 - 3.5e-16 59.7 156.8 0.00026 21.2 18.6 10.2 1 1 10 11 11 11 6 Tropomyosin like DUF1192 PF06698.11 EGR30136.1 - 3.9e-15 55.6 90.4 0.065 13.3 0.4 16.7 15 4 4 19 19 17 9 Protein of unknown function (DUF1192) DUF4201 PF13870.6 EGR30136.1 - 1.4e-14 54.2 172.7 3.8e-05 23.5 27.9 9.0 1 1 7 8 8 8 5 Domain of unknown function (DUF4201) MAD PF05557.13 EGR30136.1 - 1.5e-14 53.4 171.6 7.6e-06 24.6 74.0 6.2 1 1 3 4 4 4 3 Mitotic checkpoint protein Uso1_p115_C PF04871.13 EGR30136.1 - 7.9e-14 52.1 123.3 3.4e-05 24.2 18.4 9.2 1 1 9 10 10 10 6 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4164 PF13747.6 EGR30136.1 - 6.8e-13 48.7 114.6 0.014 15.7 6.4 12.0 3 2 9 12 12 12 6 Domain of unknown function (DUF4164) Fib_alpha PF08702.10 EGR30136.1 - 1.3e-12 48.1 178.7 0.0005 20.3 16.6 12.1 1 1 10 11 11 11 5 Fibrinogen alpha/beta chain family TMF_TATA_bd PF12325.8 EGR30136.1 - 1.2e-11 44.8 156.7 0.0013 19.0 13.1 11.0 2 1 9 11 11 11 8 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 EGR30136.1 - 4.9e-11 43.2 159.2 0.042 14.1 13.0 11.0 1 1 10 11 11 11 5 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 EGR30136.1 - 4.2e-10 39.8 141.0 0.015 15.6 9.6 13.3 1 1 8 13 13 13 7 Biogenesis of lysosome-related organelles complex-1 subunit 2 MscS_porin PF12795.7 EGR30136.1 - 4.2e-10 39.6 184.0 0.0035 16.9 36.1 7.7 1 1 5 7 7 7 4 Mechanosensitive ion channel porin domain CENP-F_leu_zip PF10473.9 EGR30136.1 - 6.7e-10 39.1 163.5 0.0096 15.9 23.8 10.2 1 1 9 10 10 10 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 PUB PF09409.10 EGR30136.1 - 1.2e-09 38.0 4.1 0.14 12.1 0.1 4.4 3 0 0 3 3 3 3 PUB domain DUF4200 PF13863.6 EGR30136.1 - 1.2e-09 38.6 191.6 0.28 11.6 8.4 12.4 1 1 10 11 11 11 6 Domain of unknown function (DUF4200) DUF812 PF05667.11 EGR30136.1 - 1.4e-09 37.5 171.6 0.00041 19.4 32.0 6.3 1 1 5 6 6 6 4 Protein of unknown function (DUF812) GAS PF13851.6 EGR30136.1 - 1.7e-09 37.4 175.3 0.0043 16.4 31.1 9.3 1 1 7 8 8 8 4 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 EGR30136.1 - 2.3e-09 37.1 157.4 0.0095 15.9 11.1 15.3 2 2 17 19 19 19 7 TATA element modulatory factor 1 DNA binding HOOK PF05622.12 EGR30136.1 - 2.7e-09 35.8 164.2 0.013 13.7 28.3 5.0 1 1 4 5 5 5 5 HOOK protein SlyX PF04102.12 EGR30136.1 - 6.3e-09 36.3 189.0 0.048 14.3 5.2 16.6 4 4 12 16 16 15 4 SlyX PspA_IM30 PF04012.12 EGR30136.1 - 4.7e-08 32.9 146.9 0.0017 18.0 3.3 13.7 1 1 8 9 9 8 3 PspA/IM30 family Jnk-SapK_ap_N PF09744.9 EGR30136.1 - 7.1e-08 32.8 165.6 0.097 12.9 17.1 10.8 1 1 9 10 10 10 5 JNK_SAPK-associated protein-1 Tropomyosin PF00261.20 EGR30136.1 - 3.7e-07 29.8 146.1 0.12 11.8 34.6 9.2 1 1 7 8 8 8 3 Tropomyosin CEP63 PF17045.5 EGR30136.1 - 5.1e-07 29.9 171.5 0.02 14.8 29.7 7.3 1 1 5 6 6 6 3 Centrosomal protein of 63 kDa TPR_MLP1_2 PF07926.12 EGR30136.1 - 8.6e-07 29.1 162.6 0.44 10.6 14.0 11.4 1 1 8 10 10 10 5 TPR/MLP1/MLP2-like protein Ribosomal_S15 PF00312.22 EGR30136.1 - 8.8e-07 29.0 76.1 0.062 13.5 1.0 13.2 3 3 9 14 14 13 3 Ribosomal protein S15 EzrA PF06160.12 EGR30136.1 - 1e-06 27.3 157.8 8.8e-05 20.9 86.6 4.5 1 1 3 4 4 4 2 Septation ring formation regulator, EzrA CALCOCO1 PF07888.11 EGR30136.1 - 1.7e-06 27.2 151.1 0.0027 16.7 41.9 5.5 1 1 4 5 5 5 3 Calcium binding and coiled-coil domain (CALCOCO1) like HMMR_N PF15905.5 EGR30136.1 - 2.1e-06 27.5 179.2 1.2 8.5 39.1 7.5 1 1 8 9 9 9 5 Hyaluronan mediated motility receptor N-terminal Golgin_A5 PF09787.9 EGR30136.1 - 2.7e-06 27.1 177.8 0.0086 15.6 37.8 7.2 1 1 6 7 7 6 5 Golgin subfamily A member 5 Fez1 PF06818.15 EGR30136.1 - 3.1e-06 27.8 142.0 0.28 11.6 21.5 6.9 1 1 5 6 6 6 2 Fez1 FPP PF05911.11 EGR30136.1 - 1.4e-05 23.5 153.0 0.02 13.1 18.1 8.6 1 1 9 10 10 10 6 Filament-like plant protein, long coiled-coil FlaC_arch PF05377.11 EGR30136.1 - 3e-05 24.3 116.4 0.19 12.1 1.1 17.4 9 3 8 18 18 18 3 Flagella accessory protein C (FlaC) RasGAP_C PF03836.15 EGR30136.1 - 5.8e-05 23.3 34.2 0.0011 19.2 13.0 10.8 1 1 10 11 11 11 3 RasGAP C-terminus APG17 PF04108.12 EGR30136.1 - 6.3e-05 22.3 115.5 0.012 14.8 12.1 8.7 1 1 6 8 8 8 6 Autophagy protein Apg17 Lebercilin PF15619.6 EGR30136.1 - 8.1e-05 22.4 171.7 0.048 13.3 31.8 9.3 2 1 6 8 8 7 3 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 EGR30136.1 - 0.00016 21.7 124.1 0.93 9.5 10.5 11.2 1 1 9 11 11 11 6 Protein of unknown function (DUF1664) Myosin_tail_1 PF01576.19 EGR30136.1 - 0.00027 18.9 162.8 0.077 10.8 22.4 5.2 1 1 2 4 4 4 3 Myosin tail DHR10 PF18595.1 EGR30136.1 - 0.00034 20.7 186.0 0.011 15.7 23.0 10.7 1 1 13 14 14 13 4 Designed helical repeat protein 10 domain DUF4349 PF14257.6 EGR30136.1 - 0.00035 20.1 1.9 0.00035 20.1 1.9 10.9 1 1 7 9 9 8 1 Domain of unknown function (DUF4349) DUF4407 PF14362.6 EGR30136.1 - 0.00082 18.8 121.7 0.79 9.0 11.6 8.6 1 1 6 7 7 6 2 Domain of unknown function (DUF4407) TACC_C PF05010.14 EGR30136.1 - 0.0019 18.0 161.4 0.58 9.9 9.4 9.3 1 1 7 8 8 8 4 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF3584 PF12128.8 EGR30136.1 - 0.0036 14.9 159.2 0.0069 14.0 56.5 4.4 1 1 3 4 4 4 2 Protein of unknown function (DUF3584) Tnp_22_trimer PF17489.2 EGR30136.1 - 0.0086 16.0 4.7 0.0086 16.0 4.7 9.3 8 1 0 8 8 5 1 L1 transposable element trimerization domain Troponin PF00992.20 EGR30136.1 - 0.01 16.1 154.6 2.4 8.5 10.3 11.6 1 1 10 11 11 11 0 Troponin APG6_N PF17675.1 EGR30136.1 - 0.015 15.9 171.6 0.33 11.5 17.1 10.0 1 1 8 9 9 8 0 Apg6 coiled-coil region Fe-S_assembly PF04384.13 EGR30136.1 - 0.02 15.5 11.9 44 4.8 0.1 7.2 6 0 0 6 6 6 0 Iron-sulphur cluster assembly KN17_SH3 PF18131.1 EGR30136.1 - 0.022 14.9 0.5 7.4 6.8 0.0 3.5 3 0 0 3 3 2 0 KN17 SH3-like C-terminal domain KELK PF15796.5 EGR30136.1 - 0.026 15.0 160.4 0.047 14.1 3.6 10.4 7 2 3 10 10 10 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase COG5 PF10392.9 EGR30136.1 - 0.074 13.2 104.8 0.24 11.6 9.8 10.3 2 1 9 11 11 10 0 Golgi transport complex subunit 5 SCO1-SenC PF02630.14 EGR30136.1 - 0.079 12.9 9.4 2.3 8.2 0.1 5.1 4 2 0 4 4 3 0 SCO1/SenC Rootletin PF15035.6 EGR30136.1 - 0.18 11.8 159.0 0.18 11.8 27.9 7.5 1 1 4 6 6 5 0 Ciliary rootlet component, centrosome cohesion MRF_C1 PF13887.6 EGR30136.1 - 0.63 9.3 11.2 19 4.5 0.0 5.6 6 0 0 6 6 4 0 Myelin gene regulatory factor -C-terminal domain 1 Cast PF10174.9 EGR30136.1 - 0.66 8.1 143.3 1.1 7.4 56.4 4.5 1 1 3 4 4 4 0 RIM-binding protein of the cytomatrix active zone FUSC PF04632.12 EGR30136.1 - 1.2 7.6 53.6 0.88 8.0 7.9 5.8 2 1 4 6 6 6 0 Fusaric acid resistance protein family DUF724 PF05266.14 EGR30136.1 - 1.4 8.7 141.8 0.02 14.7 17.6 10.3 1 1 12 13 13 13 0 Protein of unknown function (DUF724) FAM76 PF16046.5 EGR30136.1 - 2 7.7 137.7 0.23 10.8 11.8 9.1 1 1 8 9 9 9 0 FAM76 protein HrpB7 PF09486.10 EGR30136.1 - 2.3 8.6 109.2 0.21 11.9 16.3 9.9 2 1 6 9 9 8 0 Bacterial type III secretion protein (HrpB7) bZIP_1 PF00170.21 EGR30136.1 - 3.4 7.8 135.7 0.11 12.6 1.9 17.6 10 5 8 18 18 17 0 bZIP transcription factor Laminin_II PF06009.12 EGR30136.1 - 5.7 7.0 116.3 1.1 9.2 8.7 10.5 2 1 10 12 12 12 0 Laminin Domain II UPF0242 PF06785.11 EGR30136.1 - 6.9 6.7 194.1 0.88 9.6 21.9 8.5 1 1 7 8 8 7 0 Uncharacterised protein family (UPF0242) N-terminus DUF211 PF02680.14 EGR30136.1 - 7.1 6.9 15.2 1.9 8.7 0.1 5.4 5 1 0 5 5 4 0 Uncharacterized ArCR, COG1888 SHE3 PF17078.5 EGR30136.1 - 7.8 6.1 150.0 0.023 14.4 26.8 6.5 2 1 4 6 6 5 0 SWI5-dependent HO expression protein 3 DUF2353 PF09789.9 EGR30136.1 - 8.3 5.7 151.1 2.5 7.4 25.7 6.9 1 1 5 6 6 6 0 Uncharacterized coiled-coil protein (DUF2353) ECH_1 PF00378.20 EGR30138.1 - 2.8e-83 279.1 0.3 3.2e-83 278.9 0.3 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGR30138.1 - 1.3e-35 123.5 1.1 3.4e-32 112.2 0.2 2.1 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EGR30138.1 - 0.0001 22.3 0.6 0.095 12.7 0.0 2.4 2 0 0 2 2 2 2 Peptidase family S49 JAB PF01398.21 EGR30139.1 - 3.2e-27 94.9 1.5 4.8e-27 94.3 0.0 2.1 2 1 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EGR30139.1 - 1.9e-11 44.3 1.5 3.3e-11 43.6 1.1 1.6 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EGR30139.1 - 6.4e-07 29.2 0.0 1.1e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain CFAP91 PF14738.6 EGR30140.1 - 6.9e-13 48.9 21.8 6.9e-13 48.9 21.8 4.5 4 1 0 4 4 4 1 Cilia- and flagella-associated protein 91 Myosin_head PF00063.21 EGR30141.1 - 4.6e-156 520.9 37.9 4.6e-156 520.9 37.9 2.2 2 1 0 2 2 2 1 Myosin head (motor domain) RCC1 PF00415.18 EGR30141.1 - 1.7e-34 118.2 3.3 5.5e-10 39.7 0.1 5.9 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Clat_adaptor_s PF01217.20 EGR30141.1 - 7.5e-25 87.5 6.6 7.5e-25 87.5 6.6 3.7 4 0 0 4 4 4 1 Clathrin adaptor complex small chain RCC1_2 PF13540.6 EGR30141.1 - 8.3e-15 54.2 14.2 3.1e-06 26.8 0.3 5.7 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat IQ PF00612.27 EGR30141.1 - 8.8e-07 28.2 41.3 0.0045 16.7 0.3 6.8 6 0 0 6 6 6 4 IQ calmodulin-binding motif Mito_carr PF00153.27 EGR30142.1 - 3.6e-46 155.0 3.9 4.6e-16 58.5 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Histone_H2A_C PF16211.5 EGR30143.1 - 7.7e-18 63.9 0.4 1.5e-17 63.0 0.4 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGR30143.1 - 1.8e-14 54.3 0.0 2.5e-14 53.8 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGR30143.1 - 4.2e-06 27.0 0.0 6.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YihI PF04220.12 EGR30143.1 - 0.091 12.5 0.1 0.16 11.7 0.1 1.5 1 1 0 1 1 1 0 Der GTPase activator (YihI) RRM_1 PF00076.22 EGR30144.1 - 8.9e-17 60.7 0.2 2.7e-12 46.3 0.1 2.9 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RanBP PF00641.18 EGR30144.1 - 9.8e-08 31.2 6.0 9.8e-08 31.2 6.0 1.6 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others RRM_occluded PF16842.5 EGR30144.1 - 0.066 13.1 0.0 0.63 9.9 0.0 2.1 2 0 0 2 2 2 0 Occluded RNA-recognition motif ADK_lid PF05191.14 EGR30144.1 - 1.3 9.1 6.0 3.4 7.7 0.2 3.3 2 1 1 3 3 3 0 Adenylate kinase, active site lid Mob1_phocein PF03637.17 EGR30145.1 - 8.4e-41 139.8 0.1 9.8e-41 139.6 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family zf-CCCH PF00642.24 EGR30146.1 - 4.1e-11 42.5 16.9 6.3e-07 29.1 4.0 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGR30146.1 - 3.3e-05 23.8 24.1 0.00095 19.1 7.6 2.6 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EGR30146.1 - 0.0012 19.5 26.3 0.0068 17.1 8.3 3.5 3 1 0 3 3 3 2 Torus domain zf-CCCH_2 PF14608.6 EGR30146.1 - 0.012 16.1 15.5 0.1 13.1 3.7 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 EGR30146.1 - 0.038 13.8 3.8 0.038 13.8 3.8 2.5 2 0 0 2 2 2 0 CCCH-type zinc finger EutA PF06277.11 EGR30146.1 - 8.5 5.1 11.1 7 5.4 2.5 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutA Pkinase PF00069.25 EGR30147.1 - 3.2e-74 249.6 0.1 3.2e-74 249.6 0.1 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30147.1 - 4.4e-35 121.2 0.1 4.1e-32 111.5 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 EGR30147.1 - 2.1e-05 24.0 0.1 3.5e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGR30147.1 - 0.00017 21.0 0.1 0.0037 16.6 0.1 2.2 1 1 1 2 2 2 1 Kinase-like Choline_kinase PF01633.20 EGR30147.1 - 0.0024 17.5 6.1 0.0027 17.3 2.7 2.5 2 1 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EGR30147.1 - 0.0069 16.3 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4947 PF16305.5 EGR30147.1 - 0.011 15.8 0.8 0.027 14.5 0.2 2.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4947) TRAUB PF08164.12 EGR30148.1 - 1.2e-17 64.2 1.5 3.8e-17 62.6 1.5 1.9 1 0 0 1 1 1 1 Apoptosis-antagonizing transcription factor, C-terminal Prp18 PF02840.15 EGR30148.1 - 2.3 8.3 7.2 0.37 10.8 1.8 2.0 1 1 1 2 2 2 0 Prp18 domain CD36 PF01130.21 EGR30149.1 - 2.2e-27 95.7 23.2 1.2e-11 43.9 6.6 3.3 2 1 1 3 3 3 3 CD36 family Kinesin PF00225.23 EGR30151.1 - 4.9e-64 216.4 8.3 4.9e-64 216.4 8.3 4.6 3 3 1 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 EGR30151.1 - 4.5e-12 46.1 0.1 4.5e-12 46.1 0.1 2.9 3 1 0 3 3 3 1 Microtubule binding AAA_22 PF13401.6 EGR30151.1 - 0.02 15.1 0.0 0.068 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain SAP PF02037.27 EGR30151.1 - 0.029 14.1 0.3 0.098 12.4 0.0 2.1 2 0 0 2 2 2 0 SAP domain AAA_30 PF13604.6 EGR30151.1 - 0.033 13.9 0.0 0.099 12.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EGR30151.1 - 0.81 9.7 0.0 0.81 9.7 0.0 4.4 3 1 1 4 4 4 0 Helicase HerA, central domain Sugar_tr PF00083.24 EGR30153.1 - 3.4e-13 49.3 28.3 4.6e-13 48.8 28.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGR30153.1 - 2e-07 30.3 24.9 6.2e-07 28.6 11.9 2.6 2 1 1 3 3 3 2 Major Facilitator Superfamily CMV_US PF08001.11 EGR30154.1 - 6.9 5.9 7.5 8.5 5.6 7.5 1.1 1 0 0 1 1 1 0 CMV US Ribosomal_L3 PF00297.22 EGR30155.1 - 5.6e-163 542.2 12.1 6.4e-163 542.0 12.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 AAA_6 PF12774.7 EGR30157.1 - 1.8e-152 507.0 7.2 6e-148 492.1 0.1 4.9 4 1 0 4 4 4 2 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 EGR30157.1 - 2.9e-108 361.8 0.1 2.9e-108 361.8 0.1 2.4 2 0 0 2 2 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EGR30157.1 - 2.8e-95 318.6 1.2 2.8e-95 318.6 1.2 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 EGR30157.1 - 2.7e-79 264.9 1.5 3.4e-74 248.3 0.0 4.1 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_9 PF12781.7 EGR30157.1 - 3.2e-78 261.9 5.8 3.2e-78 261.9 5.8 4.7 6 0 0 6 6 5 1 ATP-binding dynein motor region DHC_N2 PF08393.13 EGR30157.1 - 9.5e-69 232.4 7.7 9.5e-69 232.4 7.7 4.1 4 0 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_lid_11 PF18198.1 EGR30157.1 - 6.9e-55 185.3 0.9 2e-52 177.3 0.0 2.9 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGR30157.1 - 3.1e-50 169.2 1.9 1.6e-44 150.8 0.0 3.8 4 0 0 4 4 3 2 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EGR30157.1 - 1.3e-30 106.2 0.9 6.9e-30 103.8 0.9 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain MT PF12777.7 EGR30157.1 - 1.8e-26 93.0 25.7 8e-26 90.9 25.7 2.0 1 1 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.14 EGR30157.1 - 2.3e-22 79.5 0.0 7.4e-08 32.5 0.0 6.0 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EGR30157.1 - 4e-16 59.0 0.3 3.6e-15 56.0 0.3 2.8 1 0 0 1 1 1 1 AAA+ lid domain AAA PF00004.29 EGR30157.1 - 5.7e-07 30.0 0.0 0.83 10.1 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGR30157.1 - 1.1e-05 25.8 0.1 7 6.9 0.0 5.0 4 0 0 4 4 4 1 AAA domain RNA_helicase PF00910.22 EGR30157.1 - 0.00019 21.8 0.3 1.1 9.7 0.0 4.5 4 0 0 4 4 3 1 RNA helicase ATG16 PF08614.11 EGR30157.1 - 0.0042 17.3 5.0 0.0042 17.3 5.0 3.1 4 0 0 4 4 1 1 Autophagy protein 16 (ATG16) AAA_16 PF13191.6 EGR30157.1 - 0.0082 16.5 0.4 3.3 8.1 0.0 4.4 4 0 0 4 4 3 1 AAA ATPase domain T2SSE PF00437.20 EGR30157.1 - 0.019 14.1 0.1 9.8 5.1 0.0 3.8 5 0 0 5 5 5 0 Type II/IV secretion system protein AAA_lid_7 PF17867.1 EGR30157.1 - 0.025 14.7 0.0 0.1 12.8 0.0 2.1 1 0 0 1 1 1 0 Midasin AAA lid domain AAA_28 PF13521.6 EGR30157.1 - 0.031 14.5 0.0 21 5.3 0.0 3.7 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EGR30157.1 - 0.16 11.7 4.6 18 5.0 0.0 4.5 5 0 0 5 5 5 0 AAA domain Mg_chelatase PF01078.21 EGR30157.1 - 0.16 11.3 1.4 13 5.1 0.1 3.9 5 0 0 5 5 5 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGR30157.1 - 0.2 12.2 16.2 0.26 11.9 0.0 6.5 9 0 0 9 9 4 0 AAA domain KxDL PF10241.9 EGR30157.1 - 0.81 10.0 23.2 0.15 12.3 3.2 4.9 3 1 0 3 3 3 0 Uncharacterized conserved protein PriX PF18689.1 EGR30158.1 - 0.02 15.2 0.8 0.041 14.2 0.3 1.8 1 1 0 1 1 1 0 Primase X VSP PF03302.13 EGR30158.1 - 0.051 12.4 16.9 0.3 9.9 5.4 1.6 1 1 0 1 1 1 0 Giardia variant-specific surface protein FeoB_associated PF12669.7 EGR30158.1 - 0.16 12.4 0.8 0.16 12.4 0.8 2.6 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Furin-like_2 PF15913.5 EGR30158.1 - 0.68 10.1 15.6 17 5.6 6.6 2.2 1 1 1 2 2 2 0 Furin-like repeat, cysteine-rich DUF4215 PF13948.6 EGR30158.1 - 0.92 10.0 24.8 0.51 10.8 9.3 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4215) EcpB_C PF18649.1 EGR30158.1 - 3 7.9 7.5 9.6 6.2 0.6 2.3 2 0 0 2 2 2 0 EcpB C-terminal domain VSP PF03302.13 EGR30159.1 - 0.0042 16.0 62.1 0.14 11.0 7.7 3.2 1 1 2 3 3 3 3 Giardia variant-specific surface protein PriX PF18689.1 EGR30159.1 - 0.053 13.9 0.1 0.19 12.1 0.1 1.9 1 0 0 1 1 1 0 Primase X FeoB_associated PF12669.7 EGR30159.1 - 0.095 13.1 1.2 0.095 13.1 1.2 5.7 5 2 0 5 5 5 0 FeoB-associated Cys-rich membrane protein VSP PF03302.13 EGR30160.1 - 0.0032 16.4 17.3 0.14 11.0 17.2 2.0 1 1 0 1 1 1 1 Giardia variant-specific surface protein FeoB_associated PF12669.7 EGR30160.1 - 0.0072 16.7 1.2 0.0072 16.7 1.2 2.3 2 0 0 2 2 2 2 FeoB-associated Cys-rich membrane protein DUF4215 PF13948.6 EGR30160.1 - 0.17 12.3 30.4 1.2 9.6 1.3 4.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4215) HSA PF07529.13 EGR30161.1 - 0.084 13.2 3.8 0.35 11.2 0.0 3.1 3 0 0 3 3 3 0 HSA PSD4 PF07631.11 EGR30161.1 - 0.089 13.3 3.0 1.6 9.3 0.3 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1592) UPF0560 PF10577.9 EGR30162.1 - 5.8 5.3 9.9 8.7 4.7 9.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 PAS_9 PF13426.7 EGR30163.1 - 2.2e-05 24.7 0.2 2.2e-05 24.7 0.2 4.7 4 1 0 4 4 4 1 PAS domain PAS PF00989.25 EGR30163.1 - 0.015 15.3 0.0 0.085 12.9 0.0 2.4 1 0 0 1 1 1 0 PAS fold Ribosomal_L24e PF01246.20 EGR30165.1 - 2.4e-21 75.7 2.5 2.4e-21 75.7 2.5 2.4 2 0 0 2 2 2 1 Ribosomal protein L24e SICA_C PF12879.7 EGR30165.1 - 0.01 15.9 1.8 0.014 15.5 1.6 1.4 1 1 0 1 1 1 1 SICA C-terminal inner membrane domain UPF0767 PF15990.5 EGR30165.1 - 0.81 9.9 6.4 0.82 9.9 4.9 1.9 1 1 0 1 1 1 0 UPF0767 family ABC_tran PF00005.27 EGR30166.1 - 1.3e-24 87.3 0.2 1.3e-24 87.3 0.2 2.6 3 0 0 3 3 3 1 ABC transporter ABC_membrane PF00664.23 EGR30166.1 - 1.5e-21 77.3 22.2 2.6e-21 76.5 22.2 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region T2SSE PF00437.20 EGR30166.1 - 0.001 18.2 0.0 0.0021 17.2 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_22 PF13401.6 EGR30166.1 - 0.0015 18.8 0.1 0.0065 16.7 0.0 2.2 2 1 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 EGR30166.1 - 0.0021 18.1 3.3 0.1 12.6 0.0 3.5 3 0 0 3 3 3 1 Dynamin family FtsK_SpoIIIE PF01580.18 EGR30166.1 - 0.0023 17.3 0.0 0.0045 16.4 0.0 1.4 1 0 0 1 1 1 1 FtsK/SpoIIIE family RFXA_RFXANK_bdg PF15289.6 EGR30166.1 - 0.0034 17.7 4.8 0.025 14.9 0.8 2.5 2 0 0 2 2 2 1 Regulatory factor X-associated C-terminal binding domain MMR_HSR1 PF01926.23 EGR30166.1 - 0.0059 16.7 0.0 0.02 15.0 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 EGR30166.1 - 0.041 13.4 1.5 0.29 10.6 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_29 PF13555.6 EGR30166.1 - 0.046 13.5 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGR30166.1 - 0.056 13.3 0.0 0.17 11.8 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase DRE2_N PF16803.5 EGR30166.1 - 0.092 13.0 1.5 0.29 11.4 0.2 2.5 3 0 0 3 3 3 0 Fe-S cluster assembly protein DRE2 N-terminus AAA_14 PF13173.6 EGR30166.1 - 0.1 12.6 10.1 1.5 8.8 3.9 3.4 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.19 EGR30166.1 - 0.17 11.3 16.4 0.16 11.4 8.1 3.4 2 2 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 EGR30166.1 - 1.1 9.3 0.0 1.1 9.3 0.0 3.3 3 1 0 3 3 3 0 Helicase HerA, central domain AAA_18 PF13238.6 EGR30166.1 - 7.5 7.1 5.7 4.3 7.9 0.3 3.4 4 1 0 4 4 4 0 AAA domain Peptidase_M8 PF01457.16 EGR30167.1 - 5.5e-34 117.8 2.0 1.1e-32 113.5 0.1 2.0 1 1 1 2 2 2 2 Leishmanolysin Zincin_1 PF06262.11 EGR30167.1 - 0.16 12.1 0.2 0.38 10.9 0.2 1.5 1 0 0 1 1 1 0 Zincin-like metallopeptidase Peptidase_M8 PF01457.16 EGR30168.1 - 4.4e-27 95.0 9.1 3.6e-22 78.7 9.1 3.1 1 1 1 2 2 2 2 Leishmanolysin EGF_2 PF07974.13 EGR30168.1 - 0.0016 18.8 12.5 0.0016 18.8 12.5 4.0 4 1 0 4 4 4 1 EGF-like domain EGF_Tenascin PF18720.1 EGR30168.1 - 0.0024 17.9 1.9 0.0024 17.9 1.9 2.3 2 0 0 2 2 2 1 Tenascin EGF domain Ras PF00071.22 EGR30169.1 - 2.4e-62 209.3 0.5 2.9e-62 209.0 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR30169.1 - 4.4e-34 117.3 0.1 1.1e-33 116.0 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR30169.1 - 1.5e-17 63.6 0.3 1.8e-17 63.3 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR30169.1 - 5.4e-07 29.7 0.3 1.5e-06 28.3 0.1 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGR30169.1 - 1e-06 28.3 0.2 1.2e-06 28.0 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EGR30169.1 - 1.5e-05 24.6 0.1 0.00043 19.8 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGR30169.1 - 0.00017 21.5 2.3 0.1 12.5 0.2 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGR30169.1 - 0.0022 17.6 0.3 0.005 16.4 0.3 1.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EGR30169.1 - 0.022 15.1 0.0 0.047 14.1 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain DUF4629 PF15442.6 EGR30169.1 - 0.078 13.2 0.8 0.13 12.5 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4629) CPT PF07931.12 EGR30169.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_6 PF12774.7 EGR30170.1 - 3.1e-153 509.5 3.2 4.9e-149 495.7 0.0 4.5 3 1 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 EGR30170.1 - 9e-102 340.4 0.0 9e-102 340.4 0.0 3.7 4 1 0 4 4 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EGR30170.1 - 5.9e-98 327.3 0.4 5.9e-98 327.3 0.4 2.5 2 0 0 2 2 1 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EGR30170.1 - 9.1e-79 263.6 8.1 9.1e-79 263.6 8.1 6.0 6 1 1 7 7 5 2 ATP-binding dynein motor region AAA_7 PF12775.7 EGR30170.1 - 1.8e-65 219.8 4.3 2e-61 206.7 0.2 4.7 4 0 0 4 4 4 2 P-loop containing dynein motor region DHC_N2 PF08393.13 EGR30170.1 - 2.3e-62 211.4 18.4 3.3e-49 168.1 7.8 7.2 6 2 0 7 7 5 2 Dynein heavy chain, N-terminal region 2 AAA_lid_11 PF18198.1 EGR30170.1 - 1.9e-60 203.4 0.2 6.1e-60 201.8 0.2 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGR30170.1 - 1e-41 141.7 2.0 9.3e-40 135.4 0.0 4.3 4 0 0 4 4 3 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EGR30170.1 - 3.6e-35 121.6 22.5 3.6e-35 121.6 22.5 2.3 3 0 0 3 3 3 1 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 EGR30170.1 - 1.6e-22 79.6 2.3 7.4e-22 77.4 0.1 3.5 3 0 0 3 3 2 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 EGR30170.1 - 4e-18 65.7 0.8 6.4e-17 61.8 0.2 3.2 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EGR30170.1 - 2.3e-15 56.8 0.6 0.00017 21.6 0.0 7.1 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGR30170.1 - 1.6e-08 34.9 0.3 0.17 12.2 0.0 5.8 5 0 0 5 5 5 2 AAA domain AAA PF00004.29 EGR30170.1 - 5.3e-08 33.4 14.7 0.00042 20.7 0.0 5.8 6 0 0 6 6 6 2 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 EGR30170.1 - 6.1e-06 25.5 2.7 0.00055 19.1 0.4 3.8 4 0 0 4 4 4 1 Type II/IV secretion system protein AAA_18 PF13238.6 EGR30170.1 - 6.7e-05 23.4 8.0 0.0083 16.7 0.0 6.6 7 0 0 7 7 5 1 AAA domain AAA_16 PF13191.6 EGR30170.1 - 6.7e-05 23.3 0.6 0.65 10.4 0.0 5.4 5 1 0 5 5 4 1 AAA ATPase domain RNA_helicase PF00910.22 EGR30170.1 - 0.0012 19.2 0.1 5.2 7.5 0.0 4.9 4 0 0 4 4 3 1 RNA helicase AAA_30 PF13604.6 EGR30170.1 - 0.0054 16.5 1.6 2.1 8.0 0.0 3.6 3 0 0 3 3 3 1 AAA domain NACHT PF05729.12 EGR30170.1 - 0.034 14.1 4.7 2.2 8.2 0.2 4.1 3 0 0 3 3 3 0 NACHT domain Viral_helicase1 PF01443.18 EGR30170.1 - 0.045 13.5 0.1 0.59 9.8 0.0 2.5 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.15 EGR30170.1 - 0.1 12.5 1.8 0.38 10.6 0.3 2.8 2 0 0 2 2 2 0 NTPase Sigma54_activat PF00158.26 EGR30170.1 - 0.22 11.2 1.2 6.9 6.3 0.0 3.4 4 0 0 4 4 3 0 Sigma-54 interaction domain AAA_19 PF13245.6 EGR30170.1 - 2.6 8.4 8.7 0.53 10.6 0.5 3.8 4 0 0 4 4 3 0 AAA domain PSD4 PF07631.11 EGR30170.1 - 9.9 6.7 7.2 5.7 7.5 2.0 3.5 2 0 0 2 2 1 0 Protein of unknown function (DUF1592) Thioredoxin PF00085.20 EGR30171.1 - 1.3e-18 66.9 0.2 1.7e-18 66.5 0.2 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGR30171.1 - 0.0001 22.6 0.6 0.0044 17.3 0.0 2.7 2 2 1 3 3 3 2 Thioredoxin-like Thioredoxin_3 PF13192.6 EGR30171.1 - 0.00069 19.6 0.0 0.0013 18.7 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin domain TraF PF13728.6 EGR30171.1 - 0.0013 18.7 0.0 0.0019 18.0 0.0 1.3 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 EGR30171.1 - 0.02 15.4 0.4 0.091 13.2 0.4 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain FPL PF09758.9 EGR30171.1 - 0.021 14.8 1.3 0.036 14.1 1.3 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein MORN PF02493.20 EGR30172.1 - 2.1e-49 162.5 79.7 2.6e-09 36.4 1.5 10.6 11 0 0 11 11 11 10 MORN repeat RXT2_N PF08595.11 EGR30172.1 - 0.32 11.0 11.7 0.52 10.3 11.7 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal FAM176 PF14851.6 EGR30172.1 - 0.56 9.9 7.4 0.95 9.1 7.4 1.3 1 0 0 1 1 1 0 FAM176 family Fzo_mitofusin PF04799.13 EGR30172.1 - 0.65 9.5 5.0 0.95 9.0 5.0 1.2 1 0 0 1 1 1 0 fzo-like conserved region DUF4820 PF16091.5 EGR30172.1 - 1.8 7.9 6.6 2.7 7.3 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) TMEM214 PF10151.9 EGR30172.1 - 4.4 5.7 11.4 6.3 5.1 11.4 1.2 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator MAM33 PF02330.16 EGR30173.1 - 4.8e-47 160.7 23.2 6.1e-47 160.3 23.2 1.1 1 0 0 1 1 1 1 Mitochondrial glycoprotein Met_synt_B12 PF02965.17 EGR30173.1 - 0.0056 16.2 4.4 0.0076 15.7 4.4 1.2 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain PH_4 PF15404.6 EGR30173.1 - 0.15 11.9 4.6 0.22 11.3 1.2 2.1 1 1 1 2 2 2 0 Pleckstrin homology domain Raptor_N PF14538.6 EGR30173.1 - 0.31 11.0 5.8 0.44 10.5 0.3 2.5 1 1 1 2 2 2 0 Raptor N-terminal CASPase like domain WRNPLPNID PF15017.6 EGR30173.1 - 1.1 10.1 9.7 0.072 14.0 3.9 2.0 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Presenilin PF01080.17 EGR30173.1 - 2.4 6.8 8.4 2.8 6.6 8.4 1.1 1 0 0 1 1 1 0 Presenilin DUF4175 PF13779.6 EGR30173.1 - 9.4 4.0 16.6 12 3.6 16.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CDP-OH_P_transf PF01066.21 EGR30174.1 - 1.3e-13 51.5 1.3 2.8e-12 47.2 0.0 3.0 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Sec7 PF01369.20 EGR30175.1 - 2.2e-56 190.4 4.4 2.2e-56 190.4 4.4 2.3 2 0 0 2 2 2 1 Sec7 domain RabGAP-TBC PF00566.18 EGR30175.1 - 3.6e-40 137.9 10.8 3.6e-40 137.9 10.8 3.1 2 1 0 2 2 2 1 Rab-GTPase-TBC domain RINGv PF12906.7 EGR30176.1 - 1.6e-12 47.4 7.6 1.6e-12 47.4 7.6 2.0 2 0 0 2 2 2 1 RING-variant domain FHA PF00498.26 EGR30176.1 - 1.2e-11 44.8 0.8 1.2e-11 44.8 0.8 2.3 3 1 0 3 3 3 1 FHA domain Yop-YscD_cpl PF16697.5 EGR30176.1 - 4.3e-07 30.2 0.1 3e-06 27.4 0.1 2.2 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 EGR30176.1 - 0.008 16.4 0.2 0.027 14.7 0.1 2.0 1 1 0 1 1 1 1 FHA domain zf-RING_2 PF13639.6 EGR30176.1 - 0.027 14.8 8.9 0.094 13.1 9.1 1.9 1 1 0 1 1 1 0 Ring finger domain FANCL_C PF11793.8 EGR30176.1 - 0.34 11.1 5.8 1 9.6 5.8 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain Pkinase PF00069.25 EGR30177.1 - 2.2e-68 230.5 0.0 2.7e-68 230.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30177.1 - 1.2e-39 136.2 0.0 1.5e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR30177.1 - 2.2e-05 23.9 0.0 6.3e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.9 EGR30177.1 - 0.05 13.1 0.0 0.076 12.5 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 EGR30177.1 - 0.053 12.3 0.0 0.087 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Response_reg PF00072.24 EGR30178.1 - 1.5e-23 83.1 1.1 4.5e-23 81.6 1.1 1.9 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 EGR30178.1 - 1.9e-20 73.4 0.6 4.7e-20 72.2 0.6 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGR30178.1 - 1.9e-09 37.4 0.1 5.1e-09 36.1 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EGR30178.1 - 0.00071 19.4 0.1 0.0021 17.9 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Actin PF00022.19 EGR30179.1 - 6.4e-84 281.9 0.1 3.2e-53 180.8 0.1 2.2 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 EGR30179.1 - 0.17 10.7 0.0 0.77 8.5 0.0 1.9 1 1 0 1 1 1 0 MreB/Mbl protein Cwf_Cwc_15 PF04889.12 EGR30180.1 - 3.5e-50 171.1 47.5 5.4e-50 170.4 47.5 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein MutS_V PF00488.21 EGR30181.1 - 3.7e-66 222.7 1.4 1.2e-65 221.1 0.7 2.2 2 0 0 2 2 2 1 MutS domain V MutS_III PF05192.18 EGR30181.1 - 6.5e-30 104.8 6.8 6.5e-30 104.8 6.8 2.4 1 1 1 2 2 2 1 MutS domain III MutS_IV PF05190.18 EGR30181.1 - 2.5e-09 37.4 3.6 1e-08 35.4 3.6 2.2 1 0 0 1 1 1 1 MutS family domain IV AAA_27 PF13514.6 EGR30181.1 - 0.011 15.4 0.0 0.031 13.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain SASP PF00269.20 EGR30181.1 - 0.071 13.1 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Small, acid-soluble spore proteins, alpha/beta type Tra_M PF05261.11 EGR30181.1 - 3.9 7.5 11.3 0.074 13.0 0.6 3.2 4 0 0 4 4 4 0 TraM protein, DNA-binding ECH_1 PF00378.20 EGR30182.1 - 4e-33 114.8 0.0 5.1e-33 114.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGR30182.1 - 4.3e-16 59.3 0.0 8.1e-16 58.4 0.0 1.4 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Ribosomal_L26 PF16906.5 EGR30183.1 - 2.7e-32 111.1 2.9 3.7e-32 110.6 2.9 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EGR30183.1 - 1.7e-08 34.1 2.9 1.7e-08 34.1 2.9 1.7 2 0 0 2 2 2 1 KOW motif NOB1_Zn_bind PF08772.11 EGR30184.1 - 9.5e-26 89.8 5.0 2.9e-25 88.2 5.0 1.9 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like PIN_6 PF17146.4 EGR30184.1 - 1.7e-22 79.7 0.2 5.7e-22 78.0 0.2 2.0 1 0 0 1 1 1 1 PIN domain of ribonuclease zf-RING_4 PF14570.6 EGR30184.1 - 0.068 13.0 3.0 0.2 11.5 3.0 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Presenilin PF01080.17 EGR30184.1 - 1.1 8.0 18.3 1.8 7.3 18.3 1.4 1 0 0 1 1 1 0 Presenilin Mem_trans PF03547.18 EGR30184.1 - 1.1 7.5 2.9 1.5 7.1 2.9 1.4 1 0 0 1 1 1 0 Membrane transport protein Folliculin PF11704.8 EGR30184.1 - 1.7 8.5 0.0 1.7 8.5 0.0 2.7 1 1 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport EMC3_TMCO1 PF01956.16 EGR30186.1 - 5.7e-10 39.2 0.1 6.2e-10 39.1 0.1 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like RRM_1 PF00076.22 EGR30187.1 - 5.8e-16 58.1 2.8 2.4e-15 56.1 0.3 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4509 PF14970.6 EGR30187.1 - 0.11 12.4 2.4 0.15 12.0 2.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4509) TagA PF12561.8 EGR30187.1 - 0.81 10.1 8.2 0.5 10.8 5.0 2.0 1 1 1 2 2 2 0 ToxR activated gene A lipoprotein domain RRM_1 PF00076.22 EGR30188.1 - 1.6e-49 165.6 8.7 2.7e-17 62.3 0.4 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGR30188.1 - 1.6e-10 40.6 1.6 0.00041 19.9 0.9 3.3 1 1 2 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGR30188.1 - 3.6e-09 36.4 0.1 0.16 11.9 0.0 3.6 4 0 0 4 4 4 3 Occluded RNA-recognition motif RRM_3 PF08777.11 EGR30188.1 - 6.9e-05 22.8 7.8 0.41 10.7 0.0 3.7 2 1 1 3 3 3 2 RNA binding motif Limkain-b1 PF11608.8 EGR30188.1 - 0.00034 20.6 0.3 2.7 8.1 0.0 3.7 3 0 0 3 3 3 1 Limkain b1 RRM_7 PF16367.5 EGR30188.1 - 0.00055 20.0 0.4 7.9 6.7 0.1 3.5 3 0 0 3 3 3 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EGR30188.1 - 0.0015 18.5 0.4 2.7 8.1 0.0 3.2 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 EGR30188.1 - 0.0063 16.8 7.6 2.6 8.3 0.2 4.6 2 2 3 5 5 5 1 Cytosolic domain of 10TM putative phosphate transporter Phage_TAC_13 PF16459.5 EGR30188.1 - 0.018 15.5 1.5 0.56 10.7 0.2 2.9 3 0 0 3 3 3 0 Phage tail assembly chaperone, TAC DbpA PF03880.15 EGR30188.1 - 0.036 14.1 0.0 14 5.8 0.0 3.6 3 0 0 3 3 3 0 DbpA RNA binding domain Corazonin PF17308.2 EGR30188.1 - 0.038 14.4 0.4 0.18 12.2 0.2 2.1 2 0 0 2 2 2 0 Pro-corazonin T4_tail_cap PF11091.8 EGR30188.1 - 0.063 12.2 0.4 0.22 10.4 0.2 1.8 2 0 0 2 2 2 0 Tail-tube assembly protein DUF1214 PF06742.11 EGR30188.1 - 0.15 12.5 0.1 0.31 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1214) SET_assoc PF11767.8 EGR30188.1 - 0.36 10.5 1.7 1.8 8.2 0.1 2.7 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated DUF4974 PF16344.5 EGR30190.1 - 8.6e-05 22.5 4.5 0.17 11.9 0.2 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF4974) DUF5331 PF17265.2 EGR30190.1 - 0.0064 16.2 0.8 3.1 7.6 0.1 2.2 2 0 0 2 2 2 2 Family of unknown function (DUF5331) FNIP PF05725.12 EGR30190.1 - 0.33 11.2 12.0 1.8 8.8 2.4 2.8 2 0 0 2 2 2 0 FNIP Repeat DUF3882 PF07066.11 EGR30190.1 - 0.87 9.6 8.9 4.2 7.4 0.8 2.3 2 0 0 2 2 2 0 Lactococcus phage M3 protein KN_motif PF12075.8 EGR30190.1 - 3.8 7.4 7.7 20 5.1 0.0 3.4 2 2 2 4 4 4 0 KN motif PP2C PF00481.21 EGR30192.1 - 2.8e-27 96.0 0.0 3.4e-27 95.7 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C DnaJ PF00226.31 EGR30193.1 - 2e-25 88.7 2.8 2e-25 88.7 2.8 2.1 2 0 0 2 2 2 1 DnaJ domain Thioredoxin PF00085.20 EGR30193.1 - 8.6e-12 45.0 4.0 1.3e-05 25.1 0.1 3.3 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EGR30193.1 - 8.4e-11 42.1 15.1 0.00037 20.5 0.9 4.3 2 1 2 4 4 4 4 Thioredoxin-like domain HyaE PF07449.11 EGR30193.1 - 9.7e-06 25.5 0.0 0.027 14.4 0.0 2.5 2 0 0 2 2 2 2 Hydrogenase-1 expression protein HyaE Thioredoxin_2 PF13098.6 EGR30193.1 - 0.0032 17.9 0.4 0.079 13.4 0.0 3.1 2 1 1 3 3 3 1 Thioredoxin-like domain QSOX_Trx1 PF18108.1 EGR30193.1 - 0.069 13.3 0.2 0.21 11.8 0.2 1.8 1 0 0 1 1 1 0 QSOX Trx-like domain zf-C3HC4_3 PF13920.6 EGR30194.1 - 1.4e-06 28.0 9.3 1.4e-06 28.0 9.3 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGR30194.1 - 0.0008 19.2 7.0 0.0033 17.2 7.0 2.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGR30194.1 - 0.0013 19.0 8.7 0.0013 19.0 8.7 3.9 5 0 0 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGR30194.1 - 0.0027 17.5 8.3 0.0027 17.5 8.3 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGR30194.1 - 0.0054 16.6 9.6 0.0054 16.6 9.6 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-met PF12874.7 EGR30194.1 - 0.14 12.6 7.6 0.7 10.4 0.4 4.9 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EGR30194.1 - 0.36 11.4 27.2 2.3 8.9 0.5 6.4 6 0 0 6 6 6 0 Zinc finger, C2H2 type Homez PF11569.8 EGR30194.1 - 1.6 8.2 5.9 20 4.7 0.3 3.4 2 1 0 2 2 2 0 Homeodomain leucine-zipper encoding, Homez Tyr-DNA_phospho PF06087.12 EGR30196.1 - 9.5e-45 153.2 6.4 1.8e-44 152.4 6.4 1.5 1 1 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 EGR30196.1 - 2.8e-05 24.0 0.3 0.042 13.7 0.0 2.7 2 1 0 2 2 2 2 PLD-like domain MnmE_helical PF12631.7 EGR30197.1 - 4.6e-44 151.1 10.5 6.1e-44 150.7 10.5 1.2 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 EGR30197.1 - 1e-32 112.8 0.0 2.8e-32 111.5 0.0 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 EGR30197.1 - 7.7e-23 80.8 0.7 7.7e-23 80.8 0.7 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGR30197.1 - 7.3e-11 41.8 3.0 1.7e-10 40.6 3.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 EGR30197.1 - 7.6e-06 25.6 6.5 0.0073 15.9 0.3 3.5 3 1 0 3 3 3 2 Elongation factor Tu GTP binding domain Arf PF00025.21 EGR30197.1 - 1.4e-05 24.6 2.8 4.9e-05 22.8 2.8 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Dynamin_N PF00350.23 EGR30197.1 - 8.7e-05 22.6 4.4 8.7e-05 22.6 4.4 3.3 3 1 0 3 3 3 1 Dynamin family Ras PF00071.22 EGR30197.1 - 0.00027 20.6 2.6 0.0012 18.4 1.6 2.5 2 0 0 2 2 2 1 Ras family AAA PF00004.29 EGR30197.1 - 0.0028 18.1 0.5 0.0028 18.1 0.5 2.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EGR30197.1 - 0.048 13.9 0.0 0.1 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGR30197.1 - 0.065 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain HydF_dimer PF18128.1 EGR30197.1 - 0.086 12.9 0.3 0.21 11.7 0.3 1.8 1 0 0 1 1 1 0 Hydrogen maturase F dimerization domain AAA_18 PF13238.6 EGR30197.1 - 0.1 13.1 0.1 0.1 13.1 0.1 3.1 3 1 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EGR30197.1 - 0.15 11.7 2.5 0.46 10.2 0.4 2.7 3 1 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 EGR30197.1 - 0.19 11.6 9.7 0.43 10.5 0.4 3.1 1 1 2 3 3 3 0 RsgA GTPase AAA_33 PF13671.6 EGR30197.1 - 0.42 10.8 1.3 7.2 6.8 0.3 3.0 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGR30197.1 - 0.62 10.5 3.2 10 6.6 0.0 3.5 3 0 0 3 3 3 0 RNA helicase NurA PF09376.10 EGR30198.1 - 0.025 14.3 0.0 0.038 13.7 0.0 1.2 1 0 0 1 1 1 0 NurA domain DUF2770 PF10968.8 EGR30198.1 - 0.07 13.1 0.8 0.07 13.1 0.8 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2770) Sec1 PF00995.23 EGR30199.1 - 8.4e-112 375.3 33.8 9.9e-112 375.0 33.8 1.0 1 0 0 1 1 1 1 Sec1 family DUF1192 PF06698.11 EGR30199.1 - 0.096 12.8 0.5 0.38 10.8 0.5 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Pyr_redox_2 PF07992.14 EGR30200.1 - 1.2e-08 34.5 0.0 0.0002 20.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Bromodomain PF00439.25 EGR30201.1 - 3.8e-21 75.0 0.9 3.8e-21 75.0 0.9 2.4 3 2 1 4 4 4 1 Bromodomain BET PF17035.5 EGR30201.1 - 9.1e-12 45.0 1.2 4.4e-11 42.8 1.2 2.3 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation DHC PF09626.10 EGR30201.1 - 0.46 11.4 4.8 0.5 11.2 2.3 2.2 1 1 1 2 2 2 0 Dihaem cytochrome c Bax1-I PF01027.20 EGR30202.1 - 1.4e-38 132.8 39.4 1.6e-38 132.7 39.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DAGAT PF03982.13 EGR30204.1 - 8.7e-23 80.7 0.1 1.4e-22 80.0 0.1 1.3 1 0 0 1 1 1 1 Diacylglycerol acyltransferase PHM7_cyt PF14703.6 EGR30205.1 - 2.8e-18 66.8 0.5 2.8e-18 66.8 0.5 3.2 3 0 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter Anoctamin PF04547.12 EGR30205.1 - 0.00032 19.7 10.2 0.0022 16.9 7.5 2.3 2 0 0 2 2 2 2 Calcium-activated chloride channel DUF4366 PF14283.6 EGR30205.1 - 0.0022 18.0 0.5 0.012 15.7 0.7 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) DUF485 PF04341.12 EGR30205.1 - 0.39 10.7 0.0 0.39 10.7 0.0 3.1 4 0 0 4 4 4 0 Protein of unknown function, DUF485 Goodbye PF17109.5 EGR30205.1 - 8.2 6.9 7.4 2.6 8.5 2.6 2.4 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain ThiF PF00899.21 EGR30207.1 - 4.4e-09 36.1 0.0 5.6e-09 35.7 0.0 1.1 1 0 0 1 1 1 1 ThiF family ThiF PF00899.21 EGR30209.1 - 6.7e-31 107.5 1.2 3.4e-23 82.3 0.3 2.7 2 1 0 2 2 2 2 ThiF family E1_FCCH PF16190.5 EGR30209.1 - 2.1e-24 85.5 0.4 6.1e-24 84.0 0.4 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain UBA_e1_thiolCys PF10585.9 EGR30209.1 - 6.1e-24 85.3 21.3 1.6e-18 67.5 5.0 4.0 2 1 1 3 3 3 2 Ubiquitin-activating enzyme active site MORN PF02493.20 EGR30209.1 - 3.2e-11 42.4 40.3 4.7e-06 26.2 1.2 6.6 6 0 0 6 6 6 4 MORN repeat E1_4HB PF16191.5 EGR30209.1 - 1.8e-05 24.8 0.2 1.8e-05 24.8 0.2 3.5 3 0 0 3 3 3 1 Ubiquitin-activating enzyme E1 four-helix bundle DUF3181 PF11378.8 EGR30209.1 - 0.025 14.9 0.5 0.08 13.3 0.5 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) Cytomega_UL84 PF06284.11 EGR30209.1 - 3.8 5.9 4.4 5.6 5.3 4.4 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein PK PF00224.21 EGR30210.1 - 2.4e-88 296.4 0.0 4.1e-88 295.6 0.0 1.3 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EGR30210.1 - 2.1e-24 86.0 0.1 4.9e-24 84.8 0.1 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EGR30210.1 - 0.0018 17.5 0.1 0.0066 15.6 0.1 1.9 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family KH_1 PF00013.29 EGR30210.1 - 0.089 12.6 0.1 6.4 6.7 0.0 3.0 2 0 0 2 2 2 0 KH domain ABC1 PF03109.16 EGR30211.1 - 1.8e-31 108.8 0.3 1.8e-31 108.8 0.3 1.9 2 0 0 2 2 2 1 ABC1 family Methyltransf_25 PF13649.6 EGR30212.1 - 9.9e-13 48.6 0.1 6.5e-12 46.0 0.0 2.4 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGR30212.1 - 1.6e-12 47.9 0.1 9.1e-12 45.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGR30212.1 - 1.9e-12 47.3 2.9 1.9e-12 47.3 2.9 2.0 1 1 2 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGR30212.1 - 5.8e-06 27.0 1.1 1.9e-05 25.3 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain E1_UFD PF09358.10 EGR30212.1 - 0.019 15.7 0.2 0.019 15.7 0.2 2.6 2 1 1 3 3 3 0 Ubiquitin fold domain FctA PF12892.7 EGR30212.1 - 0.11 13.3 0.9 0.24 12.2 0.3 2.0 2 0 0 2 2 2 0 Spy0128-like isopeptide containing domain Med4 PF10018.9 EGR30213.1 - 4.5 6.9 9.6 5.9 6.5 9.6 1.2 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 RIH_assoc PF08454.11 EGR30215.1 - 4.6e-31 106.7 8.6 4.6e-31 106.7 8.6 10.2 7 3 2 9 9 9 3 RyR and IP3R Homology associated MIR PF02815.19 EGR30216.1 - 4e-08 33.3 0.1 4e-08 33.3 0.1 2.5 2 0 0 2 2 2 1 MIR domain Metallophos PF00149.28 EGR30217.1 - 8e-22 78.7 0.6 7.1e-20 72.4 0.6 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ChpA-C PF03777.13 EGR30217.1 - 0.12 12.3 0.6 0.21 11.5 0.6 1.3 1 0 0 1 1 1 0 ChpA-C Pkinase PF00069.25 EGR30218.1 - 1e-68 231.6 0.0 1.6e-68 231.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30218.1 - 2.8e-36 125.1 0.0 3.7e-36 124.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR30218.1 - 1.7e-05 24.2 0.1 2.9e-05 23.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGR30218.1 - 0.0042 16.1 1.1 0.0078 15.2 1.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGR30218.1 - 0.024 14.5 0.1 0.089 12.7 0.1 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 EGR30218.1 - 0.035 13.7 0.1 0.1 12.2 0.0 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EGR30218.1 - 0.042 13.4 0.1 0.076 12.6 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EGR30218.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Kinase-like GDI PF00996.18 EGR30219.1 - 9.7e-200 663.6 0.5 1.1e-199 663.4 0.5 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor SH3_14 PF18343.1 EGR30219.1 - 0.067 13.3 0.1 0.16 12.1 0.1 1.7 1 1 0 1 1 1 0 Dda helicase SH3 domain WD40 PF00400.32 EGR30220.1 - 4.2e-05 24.2 5.8 0.64 11.0 0.0 5.6 5 1 0 5 5 5 2 WD domain, G-beta repeat Ion_trans PF00520.31 EGR30221.1 - 7.9e-17 61.3 27.0 1.3e-16 60.6 27.0 1.3 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGR30221.1 - 3.5e-13 49.3 4.7 3.5e-13 49.3 4.7 2.3 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 EGR30221.1 - 5e-10 39.3 0.0 9e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Pkinase PF00069.25 EGR30222.1 - 3.9e-74 249.4 1.1 3.9e-74 249.4 1.1 2.5 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30222.1 - 2.2e-41 141.9 0.1 5e-41 140.7 0.1 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EGR30222.1 - 3.6e-35 119.9 20.6 4.7e-18 65.1 0.6 4.5 3 1 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.6 EGR30222.1 - 6.8e-10 38.7 2.8 7e-09 35.4 0.0 2.9 2 1 0 3 3 3 1 Kinase-like PIN7 PF18475.1 EGR30222.1 - 3.4 8.4 10.4 0.12 13.0 2.6 2.6 2 1 1 3 3 3 0 PIN domain zf-C3HC4_4 PF15227.6 EGR30224.1 - 0.0017 18.4 2.5 0.0032 17.6 2.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EGR30224.1 - 0.0022 18.0 0.6 0.0036 17.3 0.6 1.5 1 0 0 1 1 1 1 RING-type zinc-finger v110 PF01639.17 EGR30224.1 - 0.03 14.2 1.3 0.039 13.8 1.3 1.3 1 0 0 1 1 1 0 Viral family 110 Pkinase PF00069.25 EGR30225.1 - 3.3e-30 105.4 0.0 4.2e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30225.1 - 7.7e-13 48.3 0.0 6.4e-12 45.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR30225.1 - 0.0037 16.3 0.0 0.016 14.2 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EGR30225.1 - 0.0075 15.6 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like SET_assoc PF11767.8 EGR30225.1 - 0.14 11.8 0.2 0.3 10.8 0.2 1.5 1 0 0 1 1 1 0 Histone lysine methyltransferase SET associated LLC1 PF14945.6 EGR30226.1 - 0.0016 19.0 0.1 0.0016 19.0 0.1 3.4 2 1 1 3 3 3 1 Normal lung function maintenance, Low in Lung Cancer 1 protein MORN PF02493.20 EGR30227.1 - 2.1e-56 184.6 82.3 1.9e-07 30.6 1.6 9.9 10 0 0 10 10 10 9 MORN repeat PDEase_I PF00233.19 EGR30229.1 - 1.7e-77 260.4 11.9 1.7e-77 260.4 11.9 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase DUF4407 PF14362.6 EGR30230.1 - 0.023 14.1 4.2 0.044 13.1 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) AAA_24 PF13479.6 EGR30230.1 - 0.066 12.9 1.1 0.13 11.9 0.2 2.0 2 0 0 2 2 2 0 AAA domain IFT81_CH PF18383.1 EGR30232.1 - 0.11 12.8 2.5 0.2 11.9 0.1 2.6 3 0 0 3 3 3 0 Intraflagellar transport 81 calponin homology domain DUF1642 PF07852.11 EGR30232.1 - 0.14 12.7 1.6 0.4 11.2 0.0 2.6 2 2 0 2 2 2 0 Protein of unknown function (DUF1642) GSG-1 PF07803.11 EGR30232.1 - 0.17 11.8 0.1 0.3 11.0 0.1 1.4 1 0 0 1 1 1 0 GSG1-like protein MFS_1 PF07690.16 EGR30235.1 - 1.9e-07 30.3 33.8 0.00011 21.3 11.6 2.6 2 1 1 3 3 3 3 Major Facilitator Superfamily zf-CCCH PF00642.24 EGR30236.1 - 1.4e-15 56.7 20.0 9.8e-10 38.1 5.7 2.2 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EGR30236.1 - 5.2e-07 29.3 18.1 8.3e-05 22.3 3.3 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGR30236.1 - 5.8e-07 29.4 8.4 5.8e-07 29.4 8.4 2.4 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_2 PF14608.6 EGR30236.1 - 0.0005 20.5 16.0 0.0014 19.0 3.3 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EGR30236.1 - 0.00087 20.0 1.9 0.00087 20.0 1.9 3.1 1 1 1 2 2 2 1 Torus domain BT1 PF03092.16 EGR30236.1 - 0.056 11.7 0.7 0.07 11.4 0.7 1.1 1 0 0 1 1 1 0 BT1 family Sec7 PF01369.20 EGR30237.1 - 2.9e-24 85.8 2.2 2.9e-24 85.8 2.2 1.7 2 0 0 2 2 2 1 Sec7 domain Med25 PF11232.8 EGR30237.1 - 0.055 13.4 1.2 0.11 12.5 0.4 1.8 1 1 0 1 1 1 0 Mediator complex subunit 25 PTOV activation and synapsin 2 TPR_2 PF07719.17 EGR30238.1 - 1.9e-18 65.0 19.6 0.0099 15.9 0.0 9.4 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 EGR30238.1 - 1.4e-17 62.7 21.7 0.0011 18.7 0.0 8.6 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_14 PF13428.6 EGR30238.1 - 7.5e-16 57.5 0.1 0.00066 20.3 0.0 6.8 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGR30238.1 - 1.3e-15 57.7 8.7 0.032 14.7 0.1 7.4 6 2 1 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGR30238.1 - 1.9e-13 49.5 18.1 0.01 16.0 0.4 7.9 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGR30238.1 - 1.9e-10 40.9 12.4 0.017 15.4 0.2 6.8 4 2 4 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGR30238.1 - 2.2e-10 40.2 6.5 0.35 11.4 0.8 6.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGR30238.1 - 2.9e-09 36.3 6.0 0.077 13.1 0.0 6.7 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR30238.1 - 1.1e-06 28.8 19.7 0.027 14.7 0.1 5.1 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGR30238.1 - 8.2e-06 25.9 0.0 0.32 11.2 0.0 4.4 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGR30238.1 - 1.3e-05 24.8 12.3 0.041 13.6 0.0 6.9 5 2 1 6 6 6 2 TPR repeat TPR_16 PF13432.6 EGR30238.1 - 3.6e-05 24.3 0.0 22 5.8 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGR30238.1 - 0.001 19.5 10.5 4 8.3 0.0 5.9 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_15 PF13429.6 EGR30238.1 - 0.0011 18.2 1.7 0.013 14.7 0.4 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGR30238.1 - 0.025 14.6 8.6 0.1 12.7 0.1 4.0 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EGR30238.1 - 0.053 14.0 2.1 27 5.2 0.1 3.9 4 0 0 4 4 4 0 Alkyl sulfatase dimerisation TPR_10 PF13374.6 EGR30238.1 - 3.5 7.6 12.2 35 4.5 0.2 5.4 6 0 0 6 6 6 0 Tetratricopeptide repeat ABC_membrane PF00664.23 EGR30239.1 - 3.4e-41 141.7 9.9 5e-41 141.2 9.9 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGR30239.1 - 1.4e-33 116.3 0.0 2.8e-33 115.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGR30239.1 - 6.8e-09 35.5 3.9 9.6e-07 28.4 0.2 2.5 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGR30239.1 - 2.4e-05 24.8 0.1 5.2e-05 23.7 0.1 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGR30239.1 - 0.00065 19.4 0.2 0.0017 18.1 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA PF00004.29 EGR30239.1 - 0.0011 19.4 0.4 0.0059 17.0 0.4 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGR30239.1 - 0.0016 18.7 0.2 0.011 15.9 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_21 PF13304.6 EGR30239.1 - 0.0097 15.7 0.1 0.024 14.4 0.1 1.7 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGR30239.1 - 0.017 15.1 0.1 0.039 13.9 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase G-alpha PF00503.20 EGR30239.1 - 0.021 14.0 1.3 0.03 13.5 0.0 1.8 2 1 0 2 2 2 0 G-protein alpha subunit IstB_IS21 PF01695.17 EGR30239.1 - 0.023 14.4 0.3 1 9.1 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_14 PF13173.6 EGR30239.1 - 0.026 14.6 0.0 0.6 10.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EGR30239.1 - 0.027 14.6 1.7 0.069 13.2 0.3 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain AAA_18 PF13238.6 EGR30239.1 - 0.028 15.0 0.3 0.23 12.0 0.1 2.2 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EGR30239.1 - 0.043 13.7 2.2 1.9 8.3 0.1 2.3 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 EGR30239.1 - 0.051 13.3 0.1 0.11 12.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGR30239.1 - 0.057 13.0 0.1 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain TniB PF05621.11 EGR30239.1 - 0.065 12.6 0.1 2.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein AAA_28 PF13521.6 EGR30239.1 - 0.1 12.9 0.1 0.27 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain SbcCD_C PF13558.6 EGR30239.1 - 0.1 12.8 0.4 1.2 9.4 0.4 2.4 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 EGR30239.1 - 0.17 11.6 0.8 0.92 9.2 0.8 2.3 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGR30239.1 - 1 9.4 3.4 0.79 9.8 0.9 2.3 2 1 0 2 2 1 0 50S ribosome-binding GTPase MORN PF02493.20 EGR30240.1 - 5.1e-17 60.7 33.1 3.1e-06 26.7 1.8 5.9 6 0 0 6 6 6 5 MORN repeat MORN_2 PF07661.13 EGR30240.1 - 0.022 14.9 0.9 0.022 14.9 0.9 3.6 5 0 0 5 5 5 0 MORN repeat variant SCO1-SenC PF02630.14 EGR30241.1 - 9.7e-34 116.2 0.2 3.5e-33 114.4 0.2 1.8 1 1 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 EGR30241.1 - 0.029 14.3 0.3 0.091 12.7 0.3 1.9 1 1 0 1 1 1 0 AhpC/TSA family MAF_flag10 PF01973.18 EGR30241.1 - 0.048 13.4 0.1 0.074 12.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF115 Thioredoxin_8 PF13905.6 EGR30241.1 - 0.094 13.1 0.1 0.25 11.7 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin-like HECT PF00632.25 EGR30242.1 - 1.9e-39 136.0 1.1 1.1e-33 117.0 1.0 3.2 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) DUF5442 PF17514.2 EGR30243.1 - 0.0073 16.5 0.5 0.0073 16.5 0.5 3.4 3 1 1 4 4 4 1 Family of unknown function (DUF5442) RACo_linker PF17650.1 EGR30243.1 - 0.019 14.8 0.1 0.04 13.8 0.1 1.6 1 0 0 1 1 1 0 RACo linker region DTHCT PF08070.11 EGR30243.1 - 6.2 7.6 19.0 19 6.0 19.0 1.9 1 0 0 1 1 1 0 DTHCT (NUC029) region Pkinase PF00069.25 EGR30244.1 - 4.4e-69 232.8 0.2 1.7e-68 230.8 0.2 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30244.1 - 1.8e-35 122.5 0.7 4.7e-27 94.9 0.4 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 EGR30244.1 - 1.5e-06 28.8 0.1 4.1e-06 27.4 0.1 1.9 1 0 0 1 1 1 1 Protein kinase C terminal domain Kdo PF06293.14 EGR30244.1 - 0.00077 18.9 0.2 0.0016 17.8 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR30244.1 - 0.083 12.8 0.1 0.46 10.4 0.1 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L11_N PF03946.14 EGR30245.1 - 5.9e-17 61.3 0.2 1.1e-16 60.4 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain GST_C PF00043.25 EGR30246.1 - 3.5e-10 40.0 0.1 1.5e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGR30246.1 - 2.4e-09 37.1 0.0 4.8e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGR30246.1 - 1.6e-06 28.3 0.7 3.5e-06 27.1 0.6 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGR30246.1 - 0.00068 19.9 0.1 0.0016 18.8 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGR30246.1 - 0.0031 17.9 0.0 0.0059 17.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain RNA_pol_Rpb1_5 PF04998.17 EGR30247.1 - 3.7e-82 275.7 2.4 3.7e-82 275.7 2.4 2.4 2 1 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 EGR30247.1 - 1.1e-67 228.6 12.2 1.1e-67 228.6 12.2 2.8 3 1 0 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 EGR30247.1 - 1.3e-67 227.2 4.3 1.9e-67 226.6 0.0 3.1 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EGR30247.1 - 8.1e-34 116.8 1.3 3.9e-33 114.6 0.0 2.8 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EGR30247.1 - 1.4e-24 86.1 2.3 2.4e-24 85.4 0.1 2.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 ubiquitin PF00240.23 EGR30248.1 - 8.9e-14 51.0 0.6 1.5e-13 50.3 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 EGR30248.1 - 1.8e-08 34.1 3.1 1.3e-07 31.4 0.2 2.8 2 0 0 2 2 2 1 UBA/TS-N domain Rad60-SLD PF11976.8 EGR30248.1 - 2.2e-07 30.6 0.6 3.9e-07 29.8 0.6 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EGR30248.1 - 7.2e-07 29.3 1.0 1.7e-06 28.1 1.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 EGR30248.1 - 0.0001 22.1 27.4 0.0011 18.9 13.6 2.9 1 1 1 2 2 2 2 STI1 domain Ubiquitin_2 PF14560.6 EGR30248.1 - 0.00044 20.6 0.2 0.0013 19.2 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EGR30248.1 - 0.0027 18.0 0.9 0.0057 17.0 0.9 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain DUF2407 PF10302.9 EGR30248.1 - 0.0039 17.7 0.4 0.0091 16.5 0.4 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain UN_NPL4 PF11543.8 EGR30248.1 - 0.031 14.7 0.1 0.055 14.0 0.1 1.4 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 XPC-binding PF09280.11 EGR30248.1 - 0.21 11.3 28.5 0.46 10.3 25.5 3.0 1 1 0 1 1 1 0 XPC-binding domain CUE PF02845.16 EGR30248.1 - 0.23 11.2 0.0 0.23 11.2 0.0 2.7 3 0 0 3 3 3 0 CUE domain TFIIA PF03153.13 EGR30248.1 - 0.48 10.4 15.2 0.68 9.9 15.3 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RNR_inhib PF08591.10 EGR30248.1 - 1.7 10.0 6.0 19 6.6 0.7 3.2 3 0 0 3 3 3 0 Ribonucleotide reductase inhibitor GerD PF17898.1 EGR30248.1 - 4.1 7.4 14.8 41 4.2 14.8 2.4 1 1 0 1 1 1 0 Spore germination GerD central core domain TFIIS_M PF07500.14 EGR30249.1 - 7.8e-19 68.2 8.5 7.8e-19 68.2 8.5 3.9 3 1 1 4 4 4 1 Transcription factor S-II (TFIIS), central domain PHD PF00628.29 EGR30249.1 - 0.029 14.3 7.1 0.11 12.4 7.1 2.0 1 1 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 EGR30249.1 - 0.066 13.1 4.2 0.17 11.9 4.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 MFS_1 PF07690.16 EGR30250.1 - 1.8e-09 37.0 12.8 3.3e-09 36.2 12.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Glyco_hydro_76 PF03663.14 EGR30251.1 - 2.4e-10 40.5 4.6 3.1e-10 40.1 4.6 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 76 DUF5001 PF16392.5 EGR30251.1 - 0.033 14.1 0.6 0.074 13.0 0.6 1.5 1 0 0 1 1 1 0 Ig-like domain SQS_PSY PF00494.19 EGR30252.1 - 7.6e-36 124.0 0.0 1e-35 123.5 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase CotJB PF12652.7 EGR30252.1 - 0.073 13.3 0.5 0.27 11.5 0.5 2.0 1 0 0 1 1 1 0 CotJB protein Ribosomal_S10 PF00338.22 EGR30253.1 - 2e-23 82.5 0.1 2.3e-23 82.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ferlin_C PF16165.5 EGR30253.1 - 0.05 13.5 0.7 0.067 13.1 0.7 1.2 1 0 0 1 1 1 0 Ferlin C-terminus Ribosomal_L14 PF00238.19 EGR30254.1 - 6.2e-36 123.2 0.0 8.9e-36 122.7 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Peptidase_C65 PF10275.9 EGR30255.1 - 1.5e-60 204.7 8.8 2e-60 204.3 8.8 1.2 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 EGR30255.1 - 2.2e-05 24.9 0.5 0.081 13.4 0.0 2.7 3 0 0 3 3 3 2 OTU-like cysteine protease Peptidase_C101 PF16218.5 EGR30255.1 - 0.0017 17.7 2.7 0.0023 17.3 1.0 2.0 2 1 0 2 2 2 1 Peptidase family C101 Ribosomal_S27 PF01599.19 EGR30257.1 - 3e-23 81.7 9.1 9.5e-23 80.1 5.2 2.8 2 1 0 2 2 2 1 Ribosomal protein S27a ubiquitin PF00240.23 EGR30257.1 - 0.0026 17.5 0.0 0.007 16.1 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family FAM199X PF15814.5 EGR30257.1 - 0.061 12.4 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein family FAM199X GFA PF04828.14 EGR30257.1 - 1.5 9.2 7.2 6.3 7.2 1.9 3.4 2 1 1 3 3 3 0 Glutathione-dependent formaldehyde-activating enzyme Lar_restr_allev PF14354.6 EGR30257.1 - 4.7 7.7 9.9 15 6.0 6.6 2.9 2 1 0 2 2 2 0 Restriction alleviation protein Lar Auto_anti-p27 PF06677.12 EGR30257.1 - 5.1 7.3 7.4 0.77 10.0 1.6 2.3 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) EMP70 PF02990.16 EGR30258.1 - 2e-107 360.1 33.3 3.8e-62 210.6 9.9 2.2 1 1 1 2 2 2 2 Endomembrane protein 70 K-box PF01486.17 EGR30258.1 - 0.041 14.1 0.7 0.14 12.4 0.7 1.9 1 0 0 1 1 1 0 K-box region UCH PF00443.29 EGR30259.1 - 3.5e-29 102.1 19.3 5.6e-29 101.4 19.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR30259.1 - 1e-13 51.6 21.3 2.2e-13 50.5 21.3 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EGR30259.1 - 6.6e-11 42.7 1.0 6.6e-11 42.7 1.0 3.2 2 1 0 2 2 2 1 DUSP domain HNH_5 PF14279.6 EGR30259.1 - 0.68 9.8 6.2 4.3 7.3 0.2 2.6 2 0 0 2 2 2 0 HNH endonuclease zf_UBZ PF18439.1 EGR30259.1 - 2.1 8.0 3.9 11 5.7 0.3 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Myb_DNA-binding PF00249.31 EGR30260.1 - 6.1e-16 58.3 0.1 1.8e-15 56.8 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGR30260.1 - 2.6e-05 24.4 0.7 2.6e-05 24.4 0.7 3.2 3 1 0 3 3 3 1 Myb-like DNA-binding domain DUF763 PF05559.11 EGR30260.1 - 1.3 8.1 10.9 1.9 7.6 10.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Myb_DNA-bind_7 PF15963.5 EGR30260.1 - 4.3 7.3 26.7 2.3 8.1 19.4 3.7 2 1 1 3 3 3 0 Myb DNA-binding like Pkinase PF00069.25 EGR30261.1 - 6.2e-21 74.9 1.2 6.2e-21 74.9 1.2 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30261.1 - 3.3e-12 46.3 0.1 3.3e-12 46.3 0.1 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR30261.1 - 3.4e-07 29.4 0.0 3.4e-07 29.4 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase Neur_chan_memb PF02932.16 EGR30261.1 - 2.6 8.0 7.1 3.8 7.5 7.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Abhydrolase_1 PF00561.20 EGR30262.1 - 0.016 14.9 0.1 0.028 14.1 0.1 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold adh_short PF00106.25 EGR30263.1 - 3.4e-25 88.6 0.0 6.4e-25 87.8 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGR30263.1 - 5.3e-11 42.5 0.0 1.4e-10 41.2 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGR30263.1 - 0.0021 18.0 0.0 0.0054 16.7 0.0 1.7 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EGR30263.1 - 0.021 15.1 0.1 0.047 13.9 0.0 1.6 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EGR30263.1 - 0.05 13.1 0.0 0.082 12.3 0.0 1.4 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family vATP-synt_E PF01991.18 EGR30264.1 - 2.2e-39 135.0 12.9 2.5e-39 134.8 12.9 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit NMD3 PF04981.13 EGR30265.1 - 1.1e-67 228.1 9.2 1.1e-67 228.1 9.2 2.0 2 0 0 2 2 2 1 NMD3 family zf-C2HC_2 PF13913.6 EGR30265.1 - 0.055 13.4 0.6 0.055 13.4 0.6 2.0 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Cupin_8 PF13621.6 EGR30265.1 - 2.3 7.8 9.0 0.32 10.7 0.1 3.0 2 1 1 3 3 3 0 Cupin-like domain WSD PF15613.6 EGR30265.1 - 4 8.0 12.7 10 6.7 0.7 3.1 3 1 0 3 3 3 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DHHC PF01529.20 EGR30266.1 - 3.5e-32 111.3 18.9 3.5e-32 111.3 18.9 4.0 2 2 1 3 3 3 1 DHHC palmitoyltransferase Ni_hydr_CYTB PF01292.20 EGR30266.1 - 0.0013 18.4 0.7 0.038 13.6 0.0 2.6 2 2 0 2 2 2 1 Prokaryotic cytochrome b561 B12D PF06522.11 EGR30266.1 - 0.025 14.4 0.0 2.9 7.8 0.0 2.9 2 1 0 2 2 2 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Ubiquitin_3 PF14836.6 EGR30266.1 - 0.06 13.3 1.4 0.21 11.6 0.7 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF4396 PF14342.6 EGR30266.1 - 0.11 12.9 0.4 0.11 12.9 0.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4396) C_GCAxxG_C_C PF09719.10 EGR30266.1 - 0.5 10.7 4.1 0.98 9.7 3.5 1.8 2 0 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) Pkinase_Tyr PF07714.17 EGR30267.1 - 0.00094 18.5 0.5 0.0012 18.2 0.5 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGR30267.1 - 0.0079 15.6 0.3 0.014 14.7 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain TFCD_C PF12612.8 EGR30268.1 - 1.2e-58 198.1 1.1 9.5e-58 195.2 0.0 2.9 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 EGR30268.1 - 3e-08 33.2 8.3 0.015 15.5 0.0 7.4 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 EGR30268.1 - 0.00076 19.8 0.1 1 9.8 0.0 3.9 4 0 0 4 4 4 1 HEAT repeats HEAT_EZ PF13513.6 EGR30268.1 - 0.0073 16.8 2.0 16 6.2 0.0 6.2 7 2 2 9 9 9 1 HEAT-like repeat DHHA1 PF02272.19 EGR30268.1 - 0.033 14.6 1.0 0.96 9.9 0.6 2.8 2 0 0 2 2 2 0 DHHA1 domain Intein_splicing PF14890.6 EGR30268.1 - 0.057 13.4 0.0 0.11 12.4 0.0 1.9 2 1 0 2 2 2 0 Intein splicing domain Iso_dh PF00180.20 EGR30269.1 - 1.1e-97 327.3 0.0 1.3e-97 327.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Ribosomal_L6 PF00347.23 EGR30271.1 - 9.7e-18 64.6 0.4 9.2e-15 55.1 0.0 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 NCD2 PF04905.13 EGR30271.1 - 0.037 14.0 0.3 0.037 14.0 0.3 1.7 2 1 0 2 2 2 0 NAB conserved region 2 (NCD2) Mito_carr PF00153.27 EGR30272.1 - 8.5e-53 176.3 0.1 7.4e-19 67.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4723 PF15851.5 EGR30272.1 - 0.11 12.7 0.1 5.7 7.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4723) SnAPC_2_like PF11035.8 EGR30273.1 - 0.083 13.0 4.4 0.13 12.4 4.4 1.3 1 0 0 1 1 1 0 Small nuclear RNA activating complex subunit 2, SNAP190 Myb PTPlike_phytase PF14566.6 EGR30273.1 - 1.1 9.4 7.3 0.23 11.6 3.7 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate Ribosomal_S5 PF00333.20 EGR30274.1 - 6e-14 51.8 0.0 1e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EGR30274.1 - 0.0012 18.3 0.0 0.0021 17.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain DUF1132 PF06575.12 EGR30274.1 - 0.026 14.9 0.7 0.06 13.7 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1132) 4HBT PF03061.22 EGR30277.1 - 7.8e-06 26.2 0.3 0.12 12.7 0.1 2.3 2 0 0 2 2 2 2 Thioesterase superfamily DUF5413 PF17434.2 EGR30277.1 - 0.08 13.3 0.1 0.21 11.9 0.1 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5413) Kinesin PF00225.23 EGR30278.1 - 4.7e-90 301.9 19.5 8.9e-88 294.4 19.5 2.2 1 1 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR30278.1 - 3.3e-22 79.1 10.9 6.9e-17 61.8 1.5 3.0 3 0 0 3 3 3 2 Microtubule binding Roc PF08477.13 EGR30278.1 - 0.037 14.2 0.5 5.2 7.3 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SNF2_N PF00176.23 EGR30279.1 - 9.2e-66 221.9 0.7 1.5e-65 221.2 0.7 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGR30279.1 - 7.2e-19 68.2 2.3 8.7e-18 64.7 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 EGR30279.1 - 2.7e-09 36.7 8.5 5.2e-09 35.8 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EGR30279.1 - 1.1e-07 32.0 9.7 3e-07 30.6 0.3 3.3 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Prok-RING_4 PF14447.6 EGR30279.1 - 1.4e-07 31.2 8.7 3.1e-07 30.2 8.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EGR30279.1 - 7.3e-06 25.7 11.1 1.6e-05 24.6 11.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 EGR30279.1 - 3.9e-05 23.5 0.4 0.00019 21.2 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.25 EGR30279.1 - 4.9e-05 23.1 12.5 0.00012 21.8 12.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGR30279.1 - 6.1e-05 23.3 10.8 0.00012 22.3 10.8 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGR30279.1 - 0.00012 22.0 11.2 0.00025 20.9 11.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGR30279.1 - 0.0042 17.1 6.4 0.014 15.4 6.4 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGR30279.1 - 0.013 15.8 5.2 0.035 14.4 5.2 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-UDP PF14569.6 EGR30279.1 - 0.028 14.5 3.8 0.1 12.7 3.8 2.0 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_10 PF16685.5 EGR30279.1 - 0.093 12.9 5.0 0.23 11.6 5.0 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EGR30279.1 - 0.13 12.0 11.9 0.16 11.8 5.4 2.6 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 EGR30279.1 - 1.7 8.4 7.4 4.5 7.0 7.4 1.7 1 0 0 1 1 1 0 P-11 zinc finger Rad51 PF08423.11 EGR30280.1 - 6.3e-95 317.3 0.1 7.6e-95 317.0 0.1 1.1 1 0 0 1 1 1 1 Rad51 RecA PF00154.21 EGR30280.1 - 9.5e-10 38.4 0.1 1.7e-09 37.5 0.1 1.3 1 1 0 1 1 1 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 EGR30280.1 - 5.3e-05 22.9 0.0 0.00012 21.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 EGR30280.1 - 0.00039 19.8 0.4 0.0012 18.3 0.4 1.8 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 EGR30280.1 - 0.085 12.2 0.1 0.24 10.7 0.1 1.7 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA PF00004.29 EGR30280.1 - 0.11 12.9 0.1 0.5 10.8 0.0 1.9 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) HATPase_c PF02518.26 EGR30281.1 - 1.5e-20 73.8 0.5 3.2e-20 72.7 0.2 1.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GSH_synth_ATP PF03917.17 EGR30281.1 - 0.0022 16.8 0.1 0.0023 16.8 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain HATPase_c_3 PF13589.6 EGR30281.1 - 0.0032 17.3 0.0 0.0048 16.7 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SPRY PF00622.28 EGR30281.1 - 0.048 13.8 0.1 0.079 13.1 0.1 1.4 1 0 0 1 1 1 0 SPRY domain EF-hand_2 PF09068.11 EGR30281.1 - 0.098 12.8 1.3 0.15 12.2 1.3 1.2 1 0 0 1 1 1 0 EF hand LRR_9 PF14580.6 EGR30282.1 - 1.2e-11 44.4 1.3 1.2e-11 44.4 1.3 2.1 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EGR30282.1 - 7.6e-11 42.1 15.6 4.3e-05 23.8 1.0 4.0 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGR30282.1 - 6e-07 29.1 3.5 0.00011 21.9 1.4 3.3 1 1 1 2 2 2 2 Leucine rich repeat LRR_6 PF13516.6 EGR30282.1 - 0.022 14.8 1.7 3.5 7.9 0.0 3.5 3 0 0 3 3 3 0 Leucine Rich repeat BESS PF02944.20 EGR30282.1 - 2 8.3 6.1 29 4.6 0.3 3.7 3 0 0 3 3 3 0 BESS motif LRR_1 PF00560.33 EGR30282.1 - 2.8 8.8 9.9 61 4.8 0.1 5.3 4 2 1 5 5 5 0 Leucine Rich Repeat RCC1 PF00415.18 EGR30283.1 - 9.6e-64 211.8 15.7 7.2e-15 55.3 0.1 7.6 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR30283.1 - 2.5e-33 113.2 19.9 3.1e-07 30.0 0.0 6.6 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat DnaJ_C PF01556.18 EGR30284.1 - 1.3e-37 129.1 0.6 2e-37 128.5 0.6 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGR30284.1 - 1.1e-24 86.3 3.9 1.1e-24 86.3 3.9 2.0 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGR30284.1 - 1.8e-12 47.4 16.0 3.4e-12 46.5 16.0 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGR30284.1 - 0.0012 18.8 3.9 0.47 10.4 0.2 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EGR30284.1 - 0.0017 18.4 5.5 0.63 10.1 1.8 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Lar_restr_allev PF14354.6 EGR30284.1 - 0.002 18.5 10.5 0.13 12.7 3.7 2.9 2 1 1 3 3 3 2 Restriction alleviation protein Lar Pox_RNA_pol PF03293.14 EGR30284.1 - 0.013 15.2 5.1 0.15 11.7 1.1 2.5 2 1 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit DUF1682 PF07946.14 EGR30285.1 - 9.7e-78 261.6 15.0 1.2e-77 261.3 15.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Ax_dynein_light PF10211.9 EGR30286.1 - 1.1e-66 224.4 12.1 1.4e-66 224.0 12.1 1.2 1 0 0 1 1 1 1 Axonemal dynein light chain DUF5320 PF17253.2 EGR30286.1 - 0.041 14.9 7.0 1.9 9.6 0.7 2.6 1 1 1 2 2 2 0 Family of unknown function (DUF5320) SapB_1 PF05184.15 EGR30287.1 - 0.1 12.6 1.8 0.81 9.8 0.0 2.3 2 0 0 2 2 2 0 Saposin-like type B, region 1 RIH_assoc PF08454.11 EGR30288.1 - 4.6e-36 122.7 9.8 4.6e-36 122.7 9.8 12.8 10 3 1 11 11 11 2 RyR and IP3R Homology associated Ins145_P3_rec PF08709.11 EGR30288.1 - 9.1e-14 51.2 0.7 9.1e-14 51.2 0.7 2.9 2 1 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 EGR30288.1 - 1.4e-05 25.0 0.1 1.4e-05 25.0 0.1 3.7 3 1 1 4 4 4 1 MIR domain YdaT_toxin PF06254.11 EGR30288.1 - 0.072 13.7 0.0 0.36 11.4 0.0 2.3 1 0 0 1 1 1 0 Putative bacterial toxin ydaT CD20 PF04103.15 EGR30288.1 - 2.2 8.3 3.4 22 5.1 0.1 2.9 2 0 0 2 2 2 0 CD20-like family Ion_trans PF00520.31 EGR30289.1 - 0.03 13.6 33.8 0.21 10.8 29.4 3.2 2 1 0 2 2 2 0 Ion transport protein RUN PF02759.19 EGR30289.1 - 0.1 12.5 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 RUN domain ASFV_J13L PF05568.11 EGR30289.1 - 4 7.1 4.5 20 4.9 0.3 2.6 2 0 0 2 2 2 0 African swine fever virus J13L protein MFS_1 PF07690.16 EGR30290.1 - 6e-08 32.0 13.0 7.3e-08 31.7 13.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGR30290.1 - 7.9e-05 21.7 4.4 0.00012 21.1 4.2 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 EGR30290.1 - 0.0027 16.6 3.7 0.003 16.5 3.7 1.2 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 EGR30291.1 - 0.0012 17.9 8.7 0.0014 17.6 8.7 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF3456 PF11938.8 EGR30292.1 - 0.0015 19.0 5.7 0.094 13.2 0.9 2.3 1 1 0 2 2 2 2 TLR4 regulator and MIR-interacting MSAP SapB_1 PF05184.15 EGR30292.1 - 0.0017 18.3 1.2 0.0028 17.6 0.1 2.0 2 1 0 2 2 2 1 Saposin-like type B, region 1 UBA PF00627.31 EGR30292.1 - 0.055 13.4 0.2 0.096 12.6 0.2 1.3 1 0 0 1 1 1 0 UBA/TS-N domain CdAMP_rec PF06153.11 EGR30293.1 - 0.042 14.1 3.9 1.3 9.2 0.1 3.0 3 0 0 3 3 3 0 Cyclic-di-AMP receptor Hydrolase_like PF13242.6 EGR30294.1 - 2.3e-10 40.4 0.0 3.6e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 EGR30294.1 - 7.5e-06 26.1 0.5 0.00022 21.4 0.0 2.2 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGR30294.1 - 0.0036 17.6 0.0 0.0063 16.8 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Glyco_hydro_7 PF00840.20 EGR30294.1 - 0.11 11.2 0.8 0.14 10.8 0.1 1.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 7 Coatomer_E PF04733.14 EGR30295.1 - 7.3e-19 68.3 13.5 3.6e-18 66.0 13.5 1.8 1 1 0 1 1 1 1 Coatomer epsilon subunit ANAPC3 PF12895.7 EGR30295.1 - 0.0001 22.4 4.4 0.0086 16.3 0.6 3.1 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGR30295.1 - 0.00031 21.2 0.3 0.013 16.0 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat I_LWEQ PF01608.17 EGR30295.1 - 0.041 14.1 0.2 0.11 12.8 0.2 1.7 1 1 0 1 1 1 0 I/LWEQ domain TPR_2 PF07719.17 EGR30295.1 - 3.1 8.2 9.8 31 5.0 0.1 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat PHP PF02811.19 EGR30295.1 - 6.7 7.0 9.2 47 4.2 9.2 2.2 1 1 0 1 1 1 0 PHP domain DHHC PF01529.20 EGR30296.1 - 7.4e-22 77.9 16.6 1.1e-21 77.3 16.6 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Sec62 PF03839.16 EGR30296.1 - 0.03 13.8 3.8 0.036 13.6 3.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Copine PF07002.16 EGR30297.1 - 6.3e-55 186.0 0.0 8.7e-55 185.5 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 EGR30297.1 - 8.8e-22 77.4 3.0 8.9e-13 48.4 0.1 2.4 1 1 1 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EGR30297.1 - 8.5e-07 29.3 0.1 1.5e-06 28.4 0.1 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.6 EGR30297.1 - 0.011 15.7 0.0 0.042 13.8 0.0 2.0 1 1 0 1 1 1 0 von Willebrand factor type A domain ATP-synt_ab PF00006.25 EGR30298.1 - 5.7e-55 186.3 0.0 7.6e-55 185.9 0.0 1.1 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGR30298.1 - 8.7e-11 42.2 0.0 1.7e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Rad10 PF03834.14 EGR30298.1 - 0.17 11.9 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) DUF2630 PF10944.8 EGR30299.1 - 0.097 13.1 0.2 0.18 12.3 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2630) Mito_fiss_reg PF05308.11 EGR30300.1 - 0.0008 19.6 2.6 0.00091 19.4 2.6 1.1 1 0 0 1 1 1 1 Mitochondrial fission regulator DUF1184 PF06683.11 EGR30300.1 - 0.0076 15.8 1.0 0.0091 15.5 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1184) SF-assemblin PF06705.11 EGR30300.1 - 0.018 14.4 15.8 0.086 12.2 15.8 2.1 1 1 0 1 1 1 0 SF-assemblin/beta giardin CR6_interact PF10147.9 EGR30300.1 - 0.028 14.2 6.5 0.035 13.8 6.5 1.1 1 0 0 1 1 1 0 Growth arrest and DNA-damage-inducible proteins-interacting protein 1 GatB_Yqey PF02637.18 EGR30300.1 - 0.038 13.9 6.7 0.054 13.4 6.7 1.3 1 0 0 1 1 1 0 GatB domain DUF2321 PF10083.9 EGR30300.1 - 0.1 12.2 1.5 0.14 11.8 1.5 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) TMPIT PF07851.13 EGR30300.1 - 1 8.5 5.3 1 8.5 5.3 1.0 1 0 0 1 1 1 0 TMPIT-like protein GrpE PF01025.19 EGR30301.1 - 1.6e-35 122.2 0.1 1.8e-35 122.1 0.1 1.0 1 0 0 1 1 1 1 GrpE Pkinase PF00069.25 EGR30302.1 - 3e-54 184.1 6.1 3.6e-54 183.9 6.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30302.1 - 1.5e-31 109.6 1.6 1.8e-31 109.4 1.6 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR30302.1 - 6.9e-07 28.4 0.2 1.2e-06 27.6 0.2 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR30302.1 - 7.8e-07 29.3 0.0 0.00013 22.0 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGR30302.1 - 0.00036 20.0 1.7 0.00069 19.0 1.7 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGR30302.1 - 0.0008 19.1 6.7 0.021 14.4 0.8 2.3 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EGR30302.1 - 0.0014 18.1 1.4 0.0046 16.3 0.7 1.8 1 1 1 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.9 EGR30302.1 - 0.019 14.5 2.0 0.025 14.1 2.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL DUF1910 PF08928.10 EGR30302.1 - 0.092 12.7 3.8 0.71 9.9 1.2 2.9 1 1 0 2 2 2 0 Domain of unknown function (DUF1910) DUF4985 PF16373.5 EGR30302.1 - 0.1 13.1 0.2 0.33 11.4 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF5622 PF18533.1 EGR30302.1 - 3.9 7.7 7.3 19 5.5 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5622) PolyA_pol PF01743.20 EGR30303.1 - 5e-28 98.1 0.1 1e-27 97.1 0.1 1.5 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EGR30303.1 - 3.5e-06 26.7 0.0 8e-06 25.5 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A DUF166 PF02593.14 EGR30303.1 - 0.022 14.3 0.7 4.4 6.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function T4_Rnl2_C PF18043.1 EGR30303.1 - 0.12 12.6 3.2 0.63 10.2 0.0 3.2 4 0 0 4 4 4 0 T4 RNA ligase 2 C-terminal Arginase PF00491.21 EGR30304.1 - 1.4e-70 238.0 0.0 8.2e-70 235.5 0.0 1.8 1 1 0 1 1 1 1 Arginase family Plk4_PB2 PF18409.1 EGR30304.1 - 0.002 18.8 0.1 0.0051 17.5 0.1 1.7 1 0 0 1 1 1 1 Polo-like Kinase 4 Polo Box 2 MotY_N PF18393.1 EGR30304.1 - 0.01 16.0 0.1 0.033 14.3 0.0 1.7 2 0 0 2 2 2 0 MotY N-terminal domain CBM_3 PF00942.18 EGR30304.1 - 0.016 15.7 0.2 0.04 14.3 0.2 1.7 1 0 0 1 1 1 0 Cellulose binding domain LYTB PF02401.18 EGR30304.1 - 0.045 13.0 0.0 0.069 12.4 0.0 1.2 1 0 0 1 1 1 0 LytB protein Atg14 PF10186.9 EGR30304.1 - 0.2 10.7 3.2 0.32 10.0 3.2 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Ion_trans PF00520.31 EGR30305.1 - 4e-13 49.2 16.4 4e-13 49.2 16.4 1.9 2 0 0 2 2 2 1 Ion transport protein cNMP_binding PF00027.29 EGR30305.1 - 7.2e-13 48.4 0.0 1.2e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGR30305.1 - 1.5e-12 47.3 6.1 4.3e-12 45.8 6.1 1.8 1 0 0 1 1 1 1 Ion channel Fib_alpha PF08702.10 EGR30305.1 - 0.47 10.6 4.5 1.4 9.1 4.5 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Band_7 PF01145.25 EGR30306.1 - 0.0011 19.0 2.5 0.0013 18.8 2.1 1.3 1 1 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EGR30306.1 - 0.0053 16.5 0.3 0.0079 15.9 0.3 1.3 1 0 0 1 1 1 1 SPFH domain-Band 7 family DUF3422 PF11902.8 EGR30306.1 - 0.013 14.6 1.0 0.014 14.5 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3422) DUF3181 PF11378.8 EGR30306.1 - 0.03 14.6 0.6 0.038 14.3 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) CLZ PF16526.5 EGR30306.1 - 0.18 12.2 4.2 0.26 11.7 4.2 1.2 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels LRR_8 PF13855.6 EGR30307.1 - 0.0014 18.3 6.7 0.024 14.4 2.6 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EGR30307.1 - 1.9 9.0 18.1 0.4 11.2 2.1 4.2 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) HA2 PF04408.23 EGR30308.1 - 3.4e-21 75.5 0.0 3.4e-21 75.5 0.0 3.4 5 0 0 5 5 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGR30308.1 - 4.9e-16 58.9 0.0 1.3e-15 57.5 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGR30308.1 - 2.3e-13 50.4 0.0 7.3e-13 48.8 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGR30308.1 - 5.8e-09 36.0 0.1 2e-08 34.2 0.1 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGR30308.1 - 3.8e-06 27.2 0.1 1.2e-05 25.7 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGR30308.1 - 0.00064 19.5 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGR30308.1 - 0.0013 17.9 0.1 0.0026 16.9 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 EGR30308.1 - 0.0054 16.1 0.1 0.015 14.6 0.1 1.8 1 0 0 1 1 1 1 KaiC Flavi_DEAD PF07652.14 EGR30308.1 - 0.016 15.2 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_19 PF13245.6 EGR30308.1 - 0.017 15.4 0.0 0.045 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGR30308.1 - 0.022 14.3 0.0 0.056 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EGR30308.1 - 0.036 14.6 0.0 0.23 12.0 0.0 2.4 1 0 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 EGR30308.1 - 0.051 13.6 1.0 0.67 10.0 1.0 2.8 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 EGR30308.1 - 0.057 13.0 0.0 0.14 11.7 0.0 1.7 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.6 EGR30308.1 - 0.11 12.7 0.4 0.55 10.4 0.1 2.6 2 1 0 2 2 1 0 AAA domain AAA_16 PF13191.6 EGR30308.1 - 0.16 12.3 0.2 1.1 9.6 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain TrwB_AAD_bind PF10412.9 EGR30308.1 - 0.83 8.5 4.1 0.27 10.1 0.0 2.2 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain Roc PF08477.13 EGR30308.1 - 8.2 6.7 7.5 2.5 8.4 0.0 3.3 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase Pkinase PF00069.25 EGR30309.1 - 4.7e-27 95.0 0.1 9.6e-27 94.0 0.1 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30309.1 - 1.2e-13 51.0 0.0 2.1e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR30309.1 - 7.2e-08 31.6 0.0 9.4e-07 27.9 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGR30309.1 - 0.0014 18.0 0.0 0.0023 17.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR30309.1 - 0.017 15.1 0.0 0.67 9.8 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Furin-like_2 PF15913.5 EGR30311.1 - 3.6e-05 23.9 95.7 0.043 14.0 21.8 4.7 3 1 1 4 4 4 3 Furin-like repeat, cysteine-rich PX PF00787.24 EGR30312.1 - 6.9e-20 71.1 0.1 6.9e-20 71.1 0.1 3.6 3 2 0 4 4 4 1 PX domain DDOST_48kD PF03345.14 EGR30314.1 - 1.4e-99 333.8 3.0 1.6e-99 333.6 3.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta Pex19 PF04614.12 EGR30315.1 - 0.001 18.9 0.1 0.0012 18.6 0.1 1.2 1 0 0 1 1 1 1 Pex19 protein family Thiolase_N PF00108.23 EGR30316.1 - 4.2e-66 223.0 1.2 5e-66 222.7 0.6 1.4 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGR30316.1 - 6.1e-51 171.2 0.3 1.3e-50 170.1 0.3 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ACP_syn_III_C PF08541.10 EGR30316.1 - 0.022 14.9 0.0 0.078 13.2 0.0 1.9 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ketoacyl-synt PF00109.26 EGR30316.1 - 0.056 13.0 0.4 0.47 10.0 0.1 2.4 2 0 0 2 2 2 0 Beta-ketoacyl synthase, N-terminal domain RIH_assoc PF08454.11 EGR30317.1 - 2.3e-17 62.7 9.6 2.3e-17 62.7 9.6 11.0 10 3 1 12 12 12 1 RyR and IP3R Homology associated Ins145_P3_rec PF08709.11 EGR30317.1 - 4.1e-13 49.0 2.1 2e-11 43.5 0.7 2.7 2 0 0 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor Ion_trans PF00520.31 EGR30317.1 - 9.7e-11 41.4 19.2 2.6e-10 39.9 19.2 1.8 1 0 0 1 1 1 1 Ion transport protein EF-hand_7 PF13499.6 EGR30318.1 - 1.8e-08 34.7 3.0 2.9e-08 34.0 3.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGR30318.1 - 3.1e-08 32.6 0.1 8e-08 31.3 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 EGR30318.1 - 1.2e-06 28.3 0.5 9.7e-06 25.3 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGR30318.1 - 7.4e-05 22.4 1.3 0.00052 19.7 0.0 2.6 3 0 0 3 3 3 1 EF-hand domain DUF3384 PF11864.8 EGR30318.1 - 0.0025 16.8 0.7 0.0028 16.6 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) EF-hand_4 PF12763.7 EGR30318.1 - 0.0051 16.7 2.7 0.017 15.1 0.4 2.1 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 EGR30318.1 - 0.0056 16.1 0.2 0.016 14.7 0.1 1.9 1 1 0 1 1 1 1 EF hand DUF3958 PF13125.6 EGR30318.1 - 0.02 15.1 5.9 0.02 15.1 5.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) Caleosin PF05042.13 EGR30318.1 - 0.056 13.4 2.1 0.12 12.3 0.2 2.0 1 1 1 2 2 2 0 Caleosin related protein AbiEi_1 PF09407.10 EGR30318.1 - 0.085 13.2 0.0 0.19 12.0 0.0 1.5 2 0 0 2 2 2 0 AbiEi antitoxin C-terminal domain Acyltransf_C PF16076.5 EGR30318.1 - 0.58 10.3 3.2 0.58 10.3 1.8 1.7 1 1 1 2 2 2 0 Acyltransferase C-terminus Peptidase_M8 PF01457.16 EGR30319.1 - 3.6e-33 115.0 0.0 3.6e-33 115.0 0.0 2.4 2 1 1 3 3 3 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR30319.1 - 0.0024 17.8 10.7 0.0024 17.8 10.7 2.8 2 0 0 2 2 2 1 Tenascin EGF domain MORN PF02493.20 EGR30320.1 - 1.7e-08 33.8 10.0 7.7e-05 22.4 1.8 3.6 3 0 0 3 3 3 3 MORN repeat DAO PF01266.24 EGR30322.1 - 1.3e-26 94.0 0.0 1.5e-26 93.8 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase DUF1642 PF07852.11 EGR30322.1 - 0.03 14.9 0.1 0.21 12.1 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1642) Pyr_redox_2 PF07992.14 EGR30322.1 - 0.099 11.9 0.0 0.37 10.0 0.0 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PglD_N PF17836.1 EGR30322.1 - 1.3 9.7 5.6 15 6.3 0.1 3.6 3 1 0 3 3 3 0 PglD N-terminal domain TTL PF03133.15 EGR30323.1 - 2.4e-56 191.1 10.3 1.2e-39 136.3 0.5 4.1 2 2 2 4 4 4 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR30323.1 - 8.9e-07 28.4 0.1 2.5e-05 23.6 0.0 4.5 3 1 0 4 4 4 2 YheC/D like ATP-grasp Aldedh PF00171.22 EGR30325.1 - 1.3e-125 419.5 0.0 1.5e-125 419.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4820 PF16091.5 EGR30326.1 - 0.28 10.5 5.8 0.3 10.4 5.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CENP-B_dimeris PF09026.10 EGR30326.1 - 0.83 10.1 9.3 0.86 10.0 9.3 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4637 PF15470.6 EGR30326.1 - 3.1 7.5 9.2 2.9 7.6 9.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Pox_Ag35 PF03286.14 EGR30326.1 - 3.7 7.3 8.5 3.8 7.2 8.5 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DNA_pol_phi PF04931.13 EGR30326.1 - 5.3 5.0 10.1 5 5.1 10.1 1.0 1 0 0 1 1 1 0 DNA polymerase phi WD40 PF00400.32 EGR30327.1 - 1.1e-07 32.4 0.0 7.2e-05 23.5 0.0 2.6 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR30327.1 - 9.5e-05 22.6 0.2 0.26 11.6 0.0 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Abhydrolase_1 PF00561.20 EGR30328.1 - 7.4e-14 52.0 0.6 8.5e-13 48.5 0.6 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGR30328.1 - 1.1e-11 44.5 0.1 4.3e-11 42.6 0.1 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGR30328.1 - 1.5e-10 42.1 0.0 5.6e-10 40.2 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.13 EGR30328.1 - 0.00097 18.9 1.0 0.037 13.7 0.5 2.5 1 1 0 1 1 1 1 PGAP1-like protein Thioesterase PF00975.20 EGR30328.1 - 0.0059 16.7 0.0 0.039 14.1 0.0 2.0 1 1 1 2 2 2 1 Thioesterase domain Peptidase_S9 PF00326.21 EGR30328.1 - 0.054 13.0 0.3 10 5.5 0.0 2.5 3 0 0 3 3 3 0 Prolyl oligopeptidase family DUF676 PF05057.14 EGR30328.1 - 0.054 13.0 2.5 0.044 13.3 0.6 1.8 2 0 0 2 2 2 0 Putative serine esterase (DUF676) Kinesin PF00225.23 EGR30329.1 - 4.3e-94 315.2 14.3 4.3e-94 315.2 14.3 3.7 2 2 1 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EGR30329.1 - 1.4e-39 135.4 1.9 1.4e-39 135.4 1.9 3.9 3 1 1 4 4 4 1 Microtubule binding Pkinase PF00069.25 EGR30330.1 - 6.8e-47 160.0 4.0 9.5e-47 159.6 4.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30330.1 - 2.1e-32 112.4 0.9 3.1e-32 111.9 0.9 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR30330.1 - 5.8e-08 32.4 1.4 8.8e-07 28.5 0.3 2.6 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 EGR30330.1 - 0.0056 16.6 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family C1q PF00386.21 EGR30330.1 - 0.0084 16.3 0.4 0.034 14.3 0.1 2.2 2 0 0 2 2 2 1 C1q domain Adaptin_N PF01602.20 EGR30331.1 - 1.5e-130 436.2 24.2 2.6e-130 435.4 24.2 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGR30331.1 - 5.9e-57 192.2 15.8 3.4e-54 183.2 1.6 3.8 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGR30331.1 - 8.2e-12 45.4 0.0 0.00015 22.1 0.0 5.5 2 2 3 5 5 5 3 HEAT repeats HEAT PF02985.22 EGR30331.1 - 1.1e-06 28.4 0.7 0.0095 16.1 0.0 5.0 5 0 0 5 5 4 1 HEAT repeat Cnd3 PF12719.7 EGR30331.1 - 1.8e-05 24.1 6.9 2.2e-05 23.8 1.1 3.0 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain TIP120 PF08623.10 EGR30331.1 - 0.00014 21.7 6.0 2.3 7.9 0.2 4.1 2 1 1 3 3 3 3 TATA-binding protein interacting (TIP20) RTP1_C1 PF10363.9 EGR30331.1 - 0.00019 21.6 2.2 0.85 9.8 0.0 4.2 3 0 0 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 PA PF02225.22 EGR30331.1 - 0.002 18.1 0.0 0.0043 17.1 0.0 1.5 1 0 0 1 1 1 1 PA domain HEAT_EZ PF13513.6 EGR30331.1 - 0.0045 17.5 4.5 6.1 7.5 0.0 5.2 5 0 0 5 5 5 1 HEAT-like repeat CLASP_N PF12348.8 EGR30331.1 - 0.02 14.5 3.7 0.089 12.3 0.5 2.7 2 0 0 2 2 2 0 CLASP N terminal Arm PF00514.23 EGR30331.1 - 0.32 11.1 1.6 37 4.6 0.1 3.9 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Defensin_beta_2 PF13841.6 EGR30331.1 - 0.99 10.0 6.1 0.21 12.1 1.5 2.3 2 0 0 2 2 2 0 Beta defensin Pkinase PF00069.25 EGR30332.1 - 1.2e-63 215.0 0.2 1.4e-63 214.8 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30332.1 - 6e-22 78.2 0.0 8.9e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR30332.1 - 7.2e-07 29.4 0.0 7.5e-05 22.8 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EGR30332.1 - 0.02 14.2 0.0 0.032 13.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 EGR30332.1 - 0.097 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase C2 PF00168.30 EGR30333.1 - 1.3e-15 57.6 1.3 4.1e-06 27.0 0.1 5.1 3 1 0 3 3 3 3 C2 domain Yip1 PF04893.17 EGR30334.1 - 3.1e-09 36.8 7.9 4e-09 36.4 7.9 1.1 1 0 0 1 1 1 1 Yip1 domain CYSTM PF12734.7 EGR30334.1 - 3.4 8.1 5.5 6.1 7.2 5.5 1.4 1 0 0 1 1 1 0 Cysteine-rich TM module stress tolerance Lipocalin_4 PF13648.6 EGR30335.1 - 0.32 12.0 2.2 0.49 11.4 2.2 1.4 1 0 0 1 1 1 0 Lipocalin-like domain dNK PF01712.19 EGR30336.1 - 3.7e-46 157.6 3.6 4.4e-46 157.3 3.6 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 EGR30336.1 - 1.8e-07 31.7 0.3 5.6e-07 30.2 0.1 1.9 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 EGR30336.1 - 1.1e-05 25.7 0.0 1.5e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGR30336.1 - 0.00057 20.1 0.0 0.0044 17.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGR30336.1 - 0.00091 18.6 0.2 0.039 13.2 0.1 2.5 1 1 1 2 2 2 1 Zeta toxin Thymidylate_kin PF02223.17 EGR30336.1 - 0.00099 18.8 0.5 0.0062 16.2 0.5 2.1 1 1 0 1 1 1 1 Thymidylate kinase AAA_17 PF13207.6 EGR30336.1 - 0.0011 19.4 0.1 1.4 9.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGR30336.1 - 0.0055 17.0 0.0 0.009 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGR30336.1 - 0.0064 16.2 0.0 0.013 15.2 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGR30336.1 - 0.017 15.0 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EGR30336.1 - 0.021 15.2 0.0 0.025 15.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 EGR30336.1 - 0.026 14.1 0.0 0.053 13.1 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain GTP_EFTU PF00009.27 EGR30336.1 - 0.038 13.5 0.0 0.065 12.8 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain TsaE PF02367.17 EGR30336.1 - 0.043 13.8 0.0 0.086 12.8 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE KAP_NTPase PF07693.14 EGR30336.1 - 0.056 12.7 0.0 0.056 12.7 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain AAA_23 PF13476.6 EGR30336.1 - 0.12 12.9 4.0 0.35 11.3 0.3 2.1 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 EGR30336.1 - 0.19 12.2 0.7 0.39 11.2 0.7 1.6 1 1 0 1 1 1 0 ABC transporter 2HCT PF03390.15 EGR30337.1 - 0.37 9.4 7.4 0.55 8.8 7.4 1.2 1 0 0 1 1 1 0 2-hydroxycarboxylate transporter family Pyr_redox_2 PF07992.14 EGR30338.1 - 4e-46 157.6 0.0 5.3e-46 157.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGR30338.1 - 4e-24 85.0 0.0 7.7e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGR30338.1 - 9.4e-16 58.2 5.3 5e-13 49.4 0.2 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGR30338.1 - 4e-12 46.0 7.6 3.6e-08 33.0 1.3 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGR30338.1 - 3.1e-06 26.7 0.2 0.36 10.0 0.0 3.2 3 0 0 3 3 3 2 FAD binding domain AlaDh_PNT_C PF01262.21 EGR30338.1 - 8.3e-06 25.2 2.9 0.031 13.6 0.1 3.9 2 1 1 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EGR30338.1 - 1.5e-05 24.3 1.1 1.5e-05 24.3 1.1 1.9 3 0 0 3 3 3 1 FAD binding domain Thi4 PF01946.17 EGR30338.1 - 0.0009 18.5 0.1 0.002 17.4 0.1 1.5 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 EGR30338.1 - 0.0014 17.8 0.1 0.0014 17.8 0.1 2.9 3 1 0 3 3 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 EGR30338.1 - 0.0017 17.8 0.8 0.02 14.2 0.2 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGR30338.1 - 0.0041 17.3 3.4 0.041 14.1 0.2 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGR30338.1 - 0.012 15.3 0.3 0.012 15.3 0.3 2.1 2 1 0 2 2 2 0 FAD dependent oxidoreductase 2-Hacid_dh_C PF02826.19 EGR30338.1 - 0.023 14.0 3.2 0.065 12.6 0.0 2.7 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain HI0933_like PF03486.14 EGR30338.1 - 0.029 13.1 6.8 0.0078 15.0 1.8 2.6 2 1 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 EGR30338.1 - 0.029 13.4 0.0 0.049 12.7 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein NAD_binding_7 PF13241.6 EGR30338.1 - 0.12 12.9 0.4 0.83 10.1 0.0 2.5 3 0 0 3 3 3 0 Putative NAD(P)-binding MORN PF02493.20 EGR30339.1 - 5.8e-29 98.2 40.6 5.1e-05 22.9 0.6 7.2 7 0 0 7 7 7 6 MORN repeat EF-hand_9 PF14658.6 EGR30339.1 - 0.065 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain RabGAP-TBC PF00566.18 EGR30341.1 - 1.1e-47 162.4 7.0 1.1e-47 162.4 7.0 1.8 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Fur_reg_FbpB PF13040.6 EGR30341.1 - 3.9 7.1 9.6 32 4.2 0.2 3.9 3 0 0 3 3 3 0 Fur-regulated basic protein B UPF0258 PF06789.12 EGR30342.1 - 0.018 15.2 2.1 3.5 7.8 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0258) Crystall PF00030.19 EGR30342.1 - 0.072 13.3 0.0 0.23 11.7 0.0 1.9 1 0 0 1 1 1 0 Beta/Gamma crystallin DUF5104 PF17117.5 EGR30342.1 - 0.085 13.3 6.7 0.32 11.5 0.1 3.8 4 1 1 5 5 5 0 Domain of unknown function (DUF5104) CDP-OH_P_transf PF01066.21 EGR30344.1 - 7.6e-07 29.8 0.0 7.6e-07 29.8 0.0 4.1 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PhoLip_ATPase_N PF16209.5 EGR30345.1 - 6.9e-13 48.1 0.7 1.9e-12 46.7 0.7 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EGR30345.1 - 0.00086 18.9 0.0 0.0038 16.8 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Guanylate_cyc PF00211.20 EGR30346.1 - 1.1e-77 259.8 7.1 4.5e-42 143.7 1.7 2.6 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain PhoLip_ATPase_C PF16212.5 EGR30346.1 - 6.4e-34 117.8 36.2 6.4e-34 117.8 36.2 5.1 3 2 1 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal HemY_N PF07219.13 EGR30346.1 - 1.6 9.0 0.0 1.6 9.0 0.0 3.2 3 0 0 3 3 3 0 HemY protein N-terminus APG6_N PF17675.1 EGR30347.1 - 8.2e-05 23.1 9.6 8.2e-05 23.1 9.6 4.1 1 1 1 3 3 3 1 Apg6 coiled-coil region GIT_CC PF16559.5 EGR30347.1 - 0.017 14.9 3.2 0.017 14.9 3.2 5.5 5 1 1 6 6 6 0 GIT coiled-coil Rho guanine nucleotide exchange factor ATG16 PF08614.11 EGR30347.1 - 0.02 15.1 6.1 0.02 15.1 6.1 4.2 1 1 2 4 4 4 0 Autophagy protein 16 (ATG16) DUF812 PF05667.11 EGR30347.1 - 0.17 10.7 41.3 0.45 9.3 40.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Tli4_C PF18426.1 EGR30347.1 - 0.4 11.0 9.0 0.45 10.8 7.7 1.7 1 1 0 1 1 1 0 Tle cognate immunity protein 4 C-terminal domain Jnk-SapK_ap_N PF09744.9 EGR30347.1 - 1.1 9.4 56.7 0.051 13.8 7.7 4.0 1 1 3 4 4 4 0 JNK_SAPK-associated protein-1 DUF999 PF06198.11 EGR30347.1 - 1.4 8.9 7.2 0.4 10.7 3.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF999) Spc7 PF08317.11 EGR30347.1 - 2.7 6.8 55.3 0.021 13.7 8.7 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein bZIP_1 PF00170.21 EGR30347.1 - 9.9 6.3 51.3 0.11 12.6 3.1 7.9 3 2 6 9 9 9 0 bZIP transcription factor Kinesin PF00225.23 EGR30348.1 - 4.5e-56 190.2 3.9 2.1e-33 115.7 1.3 2.0 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EGR30348.1 - 7.8e-19 68.1 0.3 1.4e-18 67.3 0.3 1.4 1 0 0 1 1 1 1 Microtubule binding AAA_22 PF13401.6 EGR30348.1 - 0.11 12.8 0.0 0.35 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain TTL PF03133.15 EGR30349.1 - 1.9e-16 60.0 0.9 1.9e-16 60.0 0.9 1.5 1 1 1 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR30349.1 - 3e-06 26.7 0.0 4.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR30349.1 - 0.0028 17.0 0.0 0.0048 16.2 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp Clr5 PF14420.6 EGR30349.1 - 0.059 13.6 0.1 0.12 12.6 0.1 1.5 1 0 0 1 1 1 0 Clr5 domain PHTB1_N PF14727.6 EGR30350.1 - 1.9e-126 422.8 10.5 2.3e-126 422.5 10.5 1.1 1 0 0 1 1 1 1 PTHB1 N-terminus PHTB1_C PF14728.6 EGR30350.1 - 6e-30 104.6 0.4 1.5e-29 103.3 0.1 1.7 2 0 0 2 2 2 1 PTHB1 C-terminus RAB3GAP2_N PF14655.6 EGR30350.1 - 0.0019 17.6 0.2 0.0066 15.8 0.0 1.9 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus TryThrA_C PF12319.8 EGR30350.1 - 0.0067 15.9 1.0 0.017 14.6 1.0 1.6 1 0 0 1 1 1 1 Tryptophan-Threonine-rich plasmodium antigen C terminal CBFD_NFYB_HMF PF00808.23 EGR30352.1 - 5.4e-27 93.9 0.4 9.5e-27 93.1 0.4 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGR30352.1 - 0.00036 20.9 2.7 0.0011 19.3 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 NOA36 PF06524.12 EGR30352.1 - 0.017 14.4 9.0 0.026 13.9 9.0 1.3 1 0 0 1 1 1 0 NOA36 protein CENP-T_C PF15511.6 EGR30352.1 - 0.085 13.0 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold FAM176 PF14851.6 EGR30352.1 - 0.11 12.1 6.8 0.21 11.2 6.8 1.4 1 0 0 1 1 1 0 FAM176 family MAS20 PF02064.15 EGR30352.1 - 0.16 12.1 3.8 0.17 12.0 2.8 1.5 2 0 0 2 2 2 0 MAS20 protein import receptor Pox_Ag35 PF03286.14 EGR30352.1 - 0.78 9.5 12.8 1.6 8.5 12.8 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PBP1_TM PF14812.6 EGR30352.1 - 3.4 8.1 10.2 6.5 7.2 10.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Sec62 PF03839.16 EGR30352.1 - 3.9 6.9 7.7 1.1 8.8 4.7 1.5 2 0 0 2 2 2 0 Translocation protein Sec62 Metallophos PF00149.28 EGR30353.1 - 3.4e-34 119.1 0.6 4.6e-34 118.7 0.6 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Yop-YscD_ppl PF16693.5 EGR30353.1 - 0.11 11.9 0.5 0.61 9.5 0.1 1.9 2 0 0 2 2 2 0 Inner membrane component of T3SS, periplasmic domain polyprenyl_synt PF00348.17 EGR30354.1 - 6.6e-50 169.5 5.1 1.5e-48 165.1 4.4 2.0 1 1 1 2 2 2 2 Polyprenyl synthetase IBR PF01485.21 EGR30355.1 - 6.2e-11 42.4 39.1 5.9e-09 36.0 12.5 3.9 2 1 2 4 4 4 3 IBR domain, a half RING-finger domain zf_Rg PF17915.1 EGR30355.1 - 0.018 14.5 4.4 0.057 12.8 4.4 1.9 1 0 0 1 1 1 0 Reverse gyrase zinc finger TRM PF02005.16 EGR30356.1 - 5.3e-104 348.4 3.8 7e-104 348.0 3.8 1.1 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase ADK_lid PF05191.14 EGR30356.1 - 0.55 10.3 4.7 9.5 6.3 4.7 2.7 1 1 0 1 1 1 0 Adenylate kinase, active site lid Pkinase PF00069.25 EGR30357.1 - 1.9e-61 207.8 0.5 2.3e-61 207.5 0.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30357.1 - 3e-38 131.6 0.1 4.4e-38 131.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ABC1 PF03109.16 EGR30357.1 - 0.0002 21.5 0.0 0.00049 20.2 0.0 1.7 2 0 0 2 2 2 1 ABC1 family Kinase-like PF14531.6 EGR30357.1 - 0.005 16.2 0.0 0.021 14.2 0.0 2.0 1 1 0 2 2 2 1 Kinase-like Pkinase PF00069.25 EGR30358.1 - 2.7e-37 128.6 1.5 1.9e-36 125.8 0.4 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30358.1 - 7.8e-25 87.6 0.2 4.6e-24 85.1 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 EGR30358.1 - 2.5e-08 34.2 1.0 5.5e-08 33.0 1.0 1.6 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase_fungal PF17667.1 EGR30358.1 - 5.8e-06 25.3 0.0 1.7e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGR30358.1 - 0.00014 21.3 0.0 0.00027 20.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR30358.1 - 0.054 12.8 0.1 0.097 12.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR30358.1 - 0.058 13.3 0.0 0.087 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EGR30358.1 - 0.29 10.7 0.1 0.29 10.7 0.1 2.4 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 EGR30359.1 - 4.3e-21 75.5 1.6 9.4e-21 74.4 1.6 1.6 1 0 0 1 1 1 1 Protein kinase domain Kelch_5 PF13854.6 EGR30359.1 - 5e-15 55.1 3.9 8.4e-05 22.5 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 EGR30359.1 - 9.8e-14 51.2 0.1 2.1e-06 27.8 0.0 5.2 5 0 0 5 5 5 2 Galactose oxidase, central domain Pkinase_Tyr PF07714.17 EGR30359.1 - 1.4e-13 50.7 0.7 2.9e-13 49.7 0.7 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kelch_6 PF13964.6 EGR30359.1 - 2.1e-11 43.7 2.4 0.0015 18.7 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 EGR30359.1 - 4.9e-09 35.6 0.9 0.0031 17.0 0.1 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 EGR30359.1 - 5.5e-09 35.9 5.3 0.16 12.0 0.0 5.6 5 1 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 EGR30359.1 - 7.4e-06 25.7 0.9 1.5 8.9 0.0 4.2 4 0 0 4 4 4 2 Kelch motif FTA2 PF13095.6 EGR30359.1 - 0.00015 21.5 1.0 0.00015 21.5 1.0 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Sushi_2 PF09014.10 EGR30359.1 - 2.3 8.1 7.6 12 5.8 0.3 3.1 3 0 0 3 3 3 0 Beta-2-glycoprotein-1 fifth domain MORN PF02493.20 EGR30360.1 - 1.1e-51 169.7 68.8 1.8e-07 30.6 0.6 9.8 10 0 0 10 10 10 9 MORN repeat Tudor_2 PF18104.1 EGR30360.1 - 0.17 11.6 22.4 4.5 7.0 0.3 7.5 7 0 0 7 7 7 0 Jumonji domain-containing protein 2A Tudor domain Kinesin PF00225.23 EGR30362.1 - 1.4e-104 349.7 5.1 1.4e-104 349.7 5.1 4.6 4 1 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 EGR30362.1 - 6.1e-27 94.4 0.3 6.1e-27 94.4 0.3 5.5 5 2 1 6 6 6 1 Microtubule binding Pkinase PF00069.25 EGR30363.1 - 2.6e-72 243.4 7.4 2.6e-72 243.4 7.4 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30363.1 - 6.2e-39 133.8 1.6 1.2e-38 132.9 1.6 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR30363.1 - 2.9e-05 23.0 0.9 2.9e-05 23.0 0.9 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGR30363.1 - 0.00033 20.1 8.5 0.00071 19.0 0.2 3.3 2 1 1 3 3 3 2 Kinase-like POLO_box PF00659.18 EGR30363.1 - 0.00085 19.5 0.9 0.0047 17.1 0.9 2.3 1 0 0 1 1 1 1 POLO box duplicated region Kdo PF06293.14 EGR30363.1 - 0.073 12.4 0.2 0.073 12.4 0.2 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DLIC PF05783.11 EGR30364.1 - 3.3e-64 217.4 12.1 1.9e-63 215.0 12.1 1.8 1 1 0 1 1 1 1 Dynein light intermediate chain (DLIC) MukF_M PF17192.4 EGR30364.1 - 0.011 15.5 3.5 0.011 15.5 3.5 1.9 2 0 0 2 2 2 0 MukF middle domain DUF3172 PF11371.8 EGR30364.1 - 0.047 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) AAA_29 PF13555.6 EGR30364.1 - 0.071 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ThiF PF00899.21 EGR30365.1 - 1.6e-90 302.8 0.0 2.4e-64 217.0 0.0 2.1 1 1 1 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EGR30365.1 - 2.3e-72 244.0 11.7 8.8e-72 242.0 7.7 2.7 2 1 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 EGR30365.1 - 7.5e-26 90.1 1.5 7.5e-26 90.1 1.5 2.1 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 FCCH domain E1_UFD PF09358.10 EGR30365.1 - 2.7e-20 72.8 0.2 2.7e-20 72.8 0.2 2.4 3 0 0 3 3 3 1 Ubiquitin fold domain E1_4HB PF16191.5 EGR30365.1 - 4.4e-19 68.4 0.9 1e-18 67.2 0.3 2.0 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle Radial_spoke_3 PF06098.11 EGR30366.1 - 2.7e-44 151.6 10.6 2.7e-44 151.6 10.6 4.1 2 1 2 4 4 4 2 Radial spoke protein 3 Apolipoprotein PF01442.18 EGR30367.1 - 0.001 19.0 10.6 0.001 19.0 10.6 6.0 4 2 0 4 4 4 1 Apolipoprotein A1/A4/E domain ISG65-75 PF11727.8 EGR30367.1 - 0.0023 17.2 14.6 0.0023 17.2 14.6 5.5 5 2 1 7 7 7 1 Invariant surface glycoprotein TetR_C_26 PF17934.1 EGR30367.1 - 0.0058 17.0 5.3 0.0058 17.0 5.3 4.1 3 0 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain Metallophos PF00149.28 EGR30368.1 - 3.6e-07 30.9 0.3 7e-07 29.9 0.3 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase RCC1 PF00415.18 EGR30368.1 - 0.00068 20.2 0.0 0.21 12.2 0.0 2.5 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat Pro_isomerase PF00160.21 EGR30370.1 - 1.3e-48 165.3 1.1 2.5e-48 164.3 1.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FKBP_C PF00254.28 EGR30370.1 - 4.2e-32 110.3 1.4 9.5e-32 109.2 0.0 2.3 3 0 0 3 3 3 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 EGR30370.1 - 8.6e-11 41.1 1.2 3.3e-05 23.7 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGR30370.1 - 2.7e-10 39.6 4.9 1.3e-05 24.8 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGR30370.1 - 6.2e-06 26.0 0.5 0.002 18.2 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGR30370.1 - 9.8e-05 22.9 0.0 0.056 14.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGR30370.1 - 0.00013 21.6 2.4 0.074 12.8 0.2 2.9 2 1 1 3 3 3 2 TPR repeat TPR_9 PF13371.6 EGR30370.1 - 0.00028 21.0 0.0 0.00046 20.3 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGR30370.1 - 0.0024 17.7 0.8 1.3 9.2 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGR30370.1 - 0.0039 17.4 0.8 1.5 9.1 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGR30370.1 - 0.0051 17.1 0.0 0.013 15.8 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGR30370.1 - 0.0054 17.3 1.3 0.24 12.1 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGR30370.1 - 0.043 14.6 0.1 1.4 9.9 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGR30370.1 - 0.2 12.2 0.8 5.2 7.7 0.2 2.3 1 1 2 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EGR30370.1 - 0.31 11.1 2.2 0.44 10.7 0.0 2.2 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain HIT PF01230.23 EGR30371.1 - 0.017 15.9 0.0 1.7 9.4 0.0 2.5 1 1 1 2 2 2 0 HIT domain Kelch_4 PF13418.6 EGR30372.1 - 5.8e-11 42.2 0.2 0.0011 18.9 0.0 3.3 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EGR30372.1 - 1.2e-07 31.7 0.0 0.0042 17.3 0.0 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 EGR30372.1 - 2e-07 30.9 0.5 0.0046 16.9 0.1 3.5 3 1 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 EGR30372.1 - 4.9e-07 29.2 0.0 0.00076 19.0 0.0 3.1 3 0 0 3 3 3 1 Kelch motif Kelch_2 PF07646.15 EGR30372.1 - 6e-06 26.0 0.4 0.006 16.5 0.0 3.3 3 1 0 3 3 3 1 Kelch motif Kelch_3 PF13415.6 EGR30372.1 - 0.0016 18.7 0.0 2.4 8.5 0.0 3.2 3 0 0 3 3 3 1 Galactose oxidase, central domain Sortilin-Vps10 PF15902.5 EGR30373.1 - 1.4e-72 244.9 14.6 3.6e-72 243.6 14.6 1.7 1 1 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EGR30373.1 - 2.5e-38 132.1 7.5 6.5e-38 130.7 7.5 1.7 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EGR30373.1 - 0.0052 16.6 9.1 1.7 9.0 0.0 4.8 4 0 0 4 4 4 1 BNR/Asp-box repeat BNR_2 PF13088.6 EGR30373.1 - 0.049 12.9 0.0 3.2 7.0 0.0 2.4 1 1 1 2 2 2 0 BNR repeat-like domain CHB_HEX_C PF03174.13 EGR30373.1 - 0.34 10.9 1.6 35 4.5 0.0 3.0 3 0 0 3 3 3 0 Chitobiase/beta-hexosaminidase C-terminal domain SET PF00856.28 EGR30374.1 - 2.2e-08 34.7 3.2 2.2e-08 34.7 3.2 2.9 2 2 0 2 2 2 1 SET domain Guanylate_cyc PF00211.20 EGR30375.1 - 3.3e-83 277.8 11.8 5.9e-43 146.6 0.5 2.8 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain E1-E2_ATPase PF00122.20 EGR30375.1 - 4.3e-08 32.9 0.0 4.3e-08 32.9 0.0 3.8 4 1 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EGR30375.1 - 8.4e-06 26.2 0.0 0.00024 21.4 0.0 2.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase CPSF_A PF03178.15 EGR30377.1 - 0.0008 18.8 0.4 0.0008 18.8 0.4 2.4 3 0 0 3 3 3 1 CPSF A subunit region WD40 PF00400.32 EGR30377.1 - 0.0013 19.5 0.3 0.27 12.2 0.0 3.9 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR30377.1 - 0.062 13.6 4.9 10 6.5 0.1 4.7 3 3 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Syja_N PF02383.18 EGR30378.1 - 2.5e-50 171.6 6.4 7e-50 170.1 6.4 1.8 1 0 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 EGR30378.1 - 2.7e-05 23.8 0.0 4.5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Pkinase PF00069.25 EGR30379.1 - 1.4e-79 267.2 0.3 1.7e-79 266.9 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30379.1 - 9.5e-40 136.5 0.1 1.2e-39 136.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EGR30379.1 - 0.00018 22.2 0.0 0.00037 21.1 0.0 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EGR30379.1 - 0.0018 17.3 0.4 0.0028 16.6 0.4 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGR30379.1 - 0.015 14.7 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tenui_N PF05733.11 EGR30379.1 - 0.11 12.0 0.6 0.19 11.2 0.6 1.3 1 0 0 1 1 1 0 Tenuivirus/Phlebovirus nucleocapsid protein Tubulin PF00091.25 EGR30381.1 - 1.7e-63 214.4 0.3 1.7e-63 214.4 0.3 2.5 2 1 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGR30381.1 - 7e-27 94.1 0.1 1.8e-26 92.8 0.1 1.7 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_2 PF13809.6 EGR30381.1 - 7.8e-06 25.3 0.4 2.1e-05 23.9 0.0 2.0 2 0 0 2 2 2 1 Tubulin like Misat_Tub_SegII PF10644.9 EGR30381.1 - 0.0072 16.6 0.0 0.0072 16.6 0.0 3.3 3 1 1 4 4 4 1 Misato Segment II tubulin-like domain Lipase_3 PF01764.25 EGR30381.1 - 0.1 12.4 0.0 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 Lipase (class 3) Metallophos PF00149.28 EGR30382.1 - 1.3e-36 127.0 0.2 1.6e-36 126.7 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGR30382.1 - 0.0016 18.8 1.8 0.0019 18.6 0.2 2.0 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EGR30382.1 - 0.076 13.2 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain TAD2 PF18521.1 EGR30382.1 - 0.11 12.5 0.7 0.23 11.5 0.7 1.5 1 0 0 1 1 1 0 Transactivation domain 2 FHA PF00498.26 EGR30383.1 - 1e-13 51.4 1.8 1.2e-13 51.2 0.8 1.6 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EGR30383.1 - 6.4e-05 23.2 0.0 9.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FHA_2 PF17913.1 EGR30383.1 - 0.023 14.9 0.1 0.031 14.5 0.1 1.2 1 0 0 1 1 1 0 FHA domain Metallophos PF00149.28 EGR30384.1 - 9e-40 137.4 0.1 1.1e-39 137.0 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGR30384.1 - 6.1e-21 74.6 1.7 8.9e-20 70.9 0.9 2.3 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Pkinase PF00069.25 EGR30385.1 - 4e-76 255.9 2.3 5.6e-76 255.4 2.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30385.1 - 1.5e-51 175.2 0.3 2.2e-51 174.6 0.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ras PF00071.22 EGR30385.1 - 4e-18 65.5 0.5 4e-18 65.5 0.5 2.3 2 1 1 3 3 3 1 Ras family Roc PF08477.13 EGR30385.1 - 9.1e-18 64.6 2.2 4e-17 62.5 0.1 2.7 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Kinase-like PF14531.6 EGR30385.1 - 6.3e-08 32.3 0.5 2.8e-05 23.6 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 EGR30385.1 - 3.1e-07 29.7 3.0 6.9e-07 28.5 3.0 1.6 1 0 0 1 1 1 1 Haspin like kinase domain DSPc PF00782.20 EGR30385.1 - 1.4e-06 28.2 0.2 1.4e-06 28.2 0.2 3.2 3 1 1 4 4 4 1 Dual specificity phosphatase, catalytic domain Arf PF00025.21 EGR30385.1 - 7.3e-06 25.5 0.2 2e-05 24.1 0.2 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family Pkinase_fungal PF17667.1 EGR30385.1 - 3.8e-05 22.6 0.0 7.2e-05 21.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR30385.1 - 0.00081 19.4 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGR30385.1 - 0.001 18.7 8.1 0.0022 17.6 0.4 2.4 1 1 1 2 2 2 1 RIO1 family Kdo PF06293.14 EGR30385.1 - 0.0011 18.3 0.5 0.0023 17.3 0.5 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Y_phosphatase3 PF13350.6 EGR30385.1 - 0.0012 18.8 0.2 0.0036 17.3 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGR30385.1 - 0.014 15.0 1.8 0.024 14.2 0.1 2.3 2 1 0 2 2 2 0 Protein-tyrosine phosphatase YrbL-PhoP_reg PF10707.9 EGR30385.1 - 0.031 13.8 4.6 0.054 13.0 0.1 2.5 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL PTPlike_phytase PF14566.6 EGR30385.1 - 0.17 12.0 2.6 0.27 11.3 0.0 2.4 3 0 0 3 3 3 0 Inositol hexakisphosphate P16-Arc PF04699.14 EGR30386.1 - 1e-08 35.8 1.9 1.2e-08 35.6 1.9 1.1 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) IZUMO PF15005.6 EGR30386.1 - 0.037 14.5 0.3 0.037 14.5 0.3 2.0 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Tho2 PF11262.8 EGR30388.1 - 7e-22 78.0 19.4 7.5e-20 71.3 9.4 3.3 2 1 1 3 3 3 2 Transcription factor/nuclear export subunit protein 2 Inhibitor_G39P PF11417.8 EGR30388.1 - 0.011 16.3 1.2 0.045 14.3 0.2 2.7 2 0 0 2 2 2 0 Loader and inhibitor of phage G40P FHIPEP PF00771.20 EGR30388.1 - 0.41 9.1 8.3 0.12 10.8 3.3 2.0 2 0 0 2 2 2 0 FHIPEP family DDHD PF02862.17 EGR30388.1 - 7.1 6.7 12.2 21 5.2 0.3 2.2 2 0 0 2 2 2 0 DDHD domain UCH PF00443.29 EGR30389.1 - 3e-65 220.3 2.0 5.2e-65 219.5 0.0 2.4 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR30389.1 - 1.4e-10 41.3 39.5 8.3e-08 32.2 6.3 4.3 3 2 1 4 4 4 3 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EGR30389.1 - 4.3e-10 40.1 8.1 4.3e-10 40.1 8.1 4.8 4 2 0 4 4 4 1 DUSP domain zf-MYND PF01753.18 EGR30389.1 - 0.00014 21.9 14.4 0.00014 21.9 14.4 2.6 3 0 0 3 3 3 1 MYND finger Ecl1 PF12855.7 EGR30389.1 - 0.65 11.1 7.3 1.4 10.0 7.3 1.5 1 0 0 1 1 1 0 ECL1/2/3 zinc binding proteins PC4 PF02229.16 EGR30390.1 - 2.2e-24 84.8 0.5 3.2e-24 84.3 0.5 1.3 1 0 0 1 1 1 1 Transcriptional Coactivator p15 (PC4) DUF1674 PF07896.12 EGR30392.1 - 2.1e-13 50.5 0.9 3.3e-13 49.9 0.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1674) CymA PF16941.5 EGR30392.1 - 0.081 12.1 0.1 0.094 11.9 0.1 1.0 1 0 0 1 1 1 0 Putative cyclodextrin porin Glutaminase PF04960.15 EGR30393.1 - 7.6e-94 314.1 0.0 1.1e-93 313.5 0.0 1.3 1 0 0 1 1 1 1 Glutaminase Ank_2 PF12796.7 EGR30393.1 - 1.4e-39 134.6 6.6 5.7e-11 42.9 0.2 3.5 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGR30393.1 - 2.3e-22 78.8 0.1 4.5e-10 39.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGR30393.1 - 2.6e-18 66.1 0.1 1.5e-07 31.8 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR30393.1 - 4.4e-18 63.5 0.8 3.4e-07 30.1 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EGR30393.1 - 7.8e-15 54.6 0.2 8.2e-07 29.2 0.1 3.8 4 0 0 4 4 4 2 Ankyrin repeat XPB_DRD PF18458.1 EGR30393.1 - 0.19 11.7 0.0 0.95 9.4 0.0 2.1 2 0 0 2 2 2 0 Xeroderma pigmentosum group B helicase damage recognition domain RCC1 PF00415.18 EGR30394.1 - 9.6e-32 109.4 3.3 2e-06 28.3 0.1 5.2 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR30394.1 - 5.9e-13 48.2 4.3 0.011 15.5 0.1 5.1 5 0 0 5 5 5 3 Regulator of chromosome condensation (RCC1) repeat Furin-like_2 PF15913.5 EGR30395.1 - 3.5e-22 78.6 144.7 3.8e-06 27.0 18.0 9.7 1 1 6 8 8 8 6 Furin-like repeat, cysteine-rich Furin-like PF00757.20 EGR30395.1 - 0.0034 17.3 153.3 0.12 12.3 32.2 5.9 1 1 4 5 5 5 4 Furin-like cysteine rich region VSP PF03302.13 EGR30395.1 - 0.07 12.0 146.2 0.22 10.3 13.1 7.8 1 1 6 7 7 7 0 Giardia variant-specific surface protein Pkinase PF00069.25 EGR30396.1 - 1.3e-23 83.7 0.4 5e-23 81.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Thiolase_N PF00108.23 EGR30396.1 - 3.1e-13 49.7 0.0 5.6e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Pkinase_Tyr PF07714.17 EGR30396.1 - 6.1e-13 48.7 0.0 6.1e-13 48.7 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase CxC6 PF18721.1 EGR30396.1 - 0.097 13.0 0.5 0.27 11.5 0.0 2.0 2 0 0 2 2 2 0 CxC6 like cysteine cluster associated with KDZ transposases Zn_peptidase PF04228.13 EGR30396.1 - 0.68 9.3 5.1 0.4 10.1 0.1 2.1 1 1 0 2 2 2 0 Putative neutral zinc metallopeptidase Bcr-Abl_Oligo PF09036.10 EGR30397.1 - 0.085 12.9 0.5 0.085 12.9 0.5 4.4 3 2 1 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain PTA_PTB PF01515.19 EGR30397.1 - 5.3 6.3 9.5 0.068 12.5 0.8 2.2 2 1 0 2 2 2 0 Phosphate acetyl/butaryl transferase Band_7 PF01145.25 EGR30398.1 - 8.3e-06 25.9 6.0 0.00051 20.1 5.2 2.8 1 1 1 2 2 2 1 SPFH domain / Band 7 family CENP-L PF13092.6 EGR30398.1 - 0.021 15.0 0.5 0.031 14.5 0.5 1.3 1 0 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 Exop_C PF18559.1 EGR30398.1 - 0.071 13.0 3.5 0.14 12.1 3.3 1.5 1 1 0 1 1 1 0 Galactose-binding domain-like AAA PF00004.29 EGR30399.1 - 9.7e-96 317.3 0.0 7.6e-47 159.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGR30399.1 - 3.2e-24 84.5 8.5 1.9e-12 46.7 1.1 3.4 2 1 1 3 3 3 2 AAA+ lid domain CDC48_N PF02359.18 EGR30399.1 - 1.5e-19 70.0 0.5 5.6e-19 68.1 0.5 2.1 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain AAA_16 PF13191.6 EGR30399.1 - 3.2e-14 53.7 0.3 3.7e-05 24.2 0.0 4.5 3 2 0 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 EGR30399.1 - 2.3e-13 50.2 0.0 1.9e-05 24.5 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGR30399.1 - 3.2e-11 43.6 0.0 2.5e-05 24.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 EGR30399.1 - 5.5e-11 42.8 0.0 3e-05 24.2 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_5 PF07728.14 EGR30399.1 - 8.5e-10 38.8 0.1 7.1e-05 22.8 0.0 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGR30399.1 - 1e-08 35.5 0.1 0.039 14.2 0.0 4.1 2 2 1 3 3 3 2 AAA domain TIP49 PF06068.13 EGR30399.1 - 1.4e-08 34.3 0.0 0.0012 18.1 0.0 2.7 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_18 PF13238.6 EGR30399.1 - 1.3e-07 32.2 0.0 0.011 16.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 EGR30399.1 - 1.6e-07 31.2 0.3 9.2e-07 28.8 0.1 2.4 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain RNA_helicase PF00910.22 EGR30399.1 - 3.7e-07 30.5 0.0 0.017 15.5 0.0 3.5 4 0 0 4 4 2 2 RNA helicase ATPase_2 PF01637.18 EGR30399.1 - 5.4e-07 29.8 0.1 0.34 10.8 0.0 3.4 2 1 1 3 3 3 2 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EGR30399.1 - 6.5e-07 29.4 0.0 0.032 14.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EGR30399.1 - 7.4e-07 28.7 0.2 0.043 13.2 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI CDC48_2 PF02933.17 EGR30399.1 - 1.5e-06 27.9 0.0 4.9e-06 26.2 0.0 1.9 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), domain 2 AAA_25 PF13481.6 EGR30399.1 - 5.4e-06 26.1 0.2 0.83 9.2 0.0 3.5 2 1 0 3 3 3 1 AAA domain Bac_DnaA PF00308.18 EGR30399.1 - 5.8e-06 26.3 0.0 0.018 14.9 0.0 2.9 3 0 0 3 3 2 2 Bacterial dnaA protein IstB_IS21 PF01695.17 EGR30399.1 - 9.1e-06 25.5 0.0 0.12 12.2 0.1 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 EGR30399.1 - 1.4e-05 24.7 0.0 0.097 12.2 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region ABC_tran PF00005.27 EGR30399.1 - 3.3e-05 24.4 0.0 0.14 12.6 0.0 3.0 2 1 0 2 2 2 2 ABC transporter AAA_28 PF13521.6 EGR30399.1 - 4e-05 23.9 0.0 0.34 11.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain DUF815 PF05673.13 EGR30399.1 - 5.4e-05 22.5 0.0 0.021 14.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_17 PF13207.6 EGR30399.1 - 5.5e-05 23.6 0.0 0.25 11.8 0.0 2.9 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EGR30399.1 - 7.4e-05 22.6 0.0 0.0051 16.6 0.0 2.3 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 EGR30399.1 - 9.9e-05 22.3 0.0 0.5 10.4 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EGR30399.1 - 0.0001 22.1 0.2 0.23 11.2 0.0 3.0 2 1 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 EGR30399.1 - 0.00017 20.8 0.0 0.28 10.2 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 EGR30399.1 - 0.00026 20.3 0.0 0.47 9.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain Zeta_toxin PF06414.12 EGR30399.1 - 0.00027 20.3 0.0 0.65 9.2 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.12 EGR30399.1 - 0.00033 20.6 0.0 1.1 9.2 0.0 3.0 3 1 0 3 3 2 2 NACHT domain Sigma54_activat PF00158.26 EGR30399.1 - 0.00037 20.2 0.0 0.97 9.1 0.0 3.1 2 1 0 2 2 2 2 Sigma-54 interaction domain ResIII PF04851.15 EGR30399.1 - 0.0007 19.6 0.0 0.098 12.6 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Rad17 PF03215.15 EGR30399.1 - 0.0014 18.6 0.0 0.71 9.8 0.0 2.9 2 1 0 2 2 2 1 Rad17 P-loop domain PhoH PF02562.16 EGR30399.1 - 0.0017 17.8 0.2 1.6 8.1 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein ATPase PF06745.13 EGR30399.1 - 0.0023 17.3 0.1 2.6 7.3 0.0 2.8 2 1 0 2 2 2 1 KaiC Sigma54_activ_2 PF14532.6 EGR30399.1 - 0.0024 18.0 0.0 0.98 9.5 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 EGR30399.1 - 0.0028 17.5 0.0 2.7 7.9 0.0 2.8 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF2075 PF09848.9 EGR30399.1 - 0.0042 16.4 0.0 0.84 8.8 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Cytidylate_kin2 PF13189.6 EGR30399.1 - 0.0047 17.1 0.0 1.9 8.6 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family NTPase_1 PF03266.15 EGR30399.1 - 0.009 15.9 2.7 7.6 6.4 0.0 4.4 5 0 0 5 5 4 0 NTPase KAP_NTPase PF07693.14 EGR30399.1 - 0.0096 15.2 0.0 0.36 10.0 0.0 2.9 2 1 1 3 3 3 1 KAP family P-loop domain AAA_19 PF13245.6 EGR30399.1 - 0.012 15.9 0.4 6.3 7.1 0.1 3.1 2 1 1 3 3 3 0 AAA domain AAA_11 PF13086.6 EGR30399.1 - 0.019 14.7 0.0 7.2 6.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGR30399.1 - 0.025 14.3 0.0 6.7 6.5 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain SKI PF01202.22 EGR30399.1 - 0.037 14.2 0.0 8.5 6.5 0.0 2.4 2 0 0 2 2 2 0 Shikimate kinase Cytidylate_kin PF02224.18 EGR30399.1 - 0.037 13.8 0.3 7.2 6.3 0.0 2.9 3 0 0 3 3 2 0 Cytidylate kinase Zot PF05707.12 EGR30399.1 - 0.039 13.6 0.0 1.2 8.7 0.0 3.1 3 1 0 3 3 3 0 Zonular occludens toxin (Zot) AAA_30 PF13604.6 EGR30399.1 - 0.06 13.1 0.1 6.4 6.4 0.1 2.5 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 EGR30399.1 - 0.51 9.2 2.0 14 4.5 0.0 2.7 3 0 0 3 3 2 0 AFG1-like ATPase WD40 PF00400.32 EGR30400.1 - 0.0043 17.9 0.1 0.44 11.5 0.2 3.3 4 0 0 4 4 4 1 WD domain, G-beta repeat PX PF00787.24 EGR30401.1 - 1.3e-09 38.0 0.0 2.9e-09 36.9 0.0 1.7 1 0 0 1 1 1 1 PX domain betaPIX_CC PF16523.5 EGR30403.1 - 0.013 15.3 0.9 0.046 13.5 0.9 2.0 1 0 0 1 1 1 0 betaPIX coiled coil zf-B_box PF00643.24 EGR30403.1 - 0.016 15.4 3.8 0.047 13.8 3.8 1.8 1 0 0 1 1 1 0 B-box zinc finger FliT PF05400.13 EGR30403.1 - 0.044 14.6 0.7 2.6 8.9 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein FliT NYD-SP28 PF14772.6 EGR30403.1 - 0.053 13.6 5.5 0.13 12.3 5.5 1.7 1 0 0 1 1 1 0 Sperm tail NUMOD4 PF07463.11 EGR30403.1 - 0.24 11.6 3.3 0.5 10.6 0.0 2.7 3 0 0 3 3 3 0 NUMOD4 motif YtxH PF12732.7 EGR30403.1 - 1.6 9.3 4.1 1.1 9.8 2.1 1.7 2 0 0 2 2 2 0 YtxH-like protein Mit_KHE1 PF10173.9 EGR30403.1 - 2.1 8.4 8.1 3.2 7.8 8.1 1.4 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related Pkinase PF00069.25 EGR30404.1 - 4e-62 210.0 2.2 7.6e-43 146.8 1.5 3.0 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30404.1 - 8.4e-35 120.3 0.2 3.9e-30 105.0 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR30404.1 - 0.0013 17.7 0.2 0.0024 16.9 0.2 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGR30404.1 - 0.12 11.7 0.1 0.25 10.7 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR30404.1 - 0.21 11.5 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PP2C PF00481.21 EGR30405.1 - 2.1e-57 194.7 0.1 1.5e-48 165.7 0.0 2.0 1 1 1 2 2 2 2 Protein phosphatase 2C Sec3_C_2 PF15278.6 EGR30405.1 - 0.084 13.2 1.0 21 5.5 0.0 2.9 2 1 0 2 2 2 0 Sec3 exocyst complex subunit 3Beta_HSD PF01073.19 EGR30406.1 - 2.1e-06 27.0 0.0 0.047 12.7 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EGR30406.1 - 1.1e-05 25.4 0.0 3.9e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 EGR30406.1 - 0.00023 21.1 0.0 0.00056 19.9 0.0 1.6 2 0 0 2 2 2 1 KR domain NmrA PF05368.13 EGR30406.1 - 0.00032 20.3 0.0 0.00051 19.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 EGR30406.1 - 0.00088 18.8 0.0 0.0036 16.8 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EGR30406.1 - 0.0038 16.7 0.0 0.0072 15.8 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 EGR30406.1 - 0.006 15.8 0.1 0.15 11.2 0.0 2.3 1 1 0 2 2 2 1 Male sterility protein 2-Hacid_dh_C PF02826.19 EGR30406.1 - 0.0093 15.3 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EGR30406.1 - 0.029 14.9 0.0 0.053 14.1 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AlaDh_PNT_C PF01262.21 EGR30406.1 - 0.15 11.3 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain AZUL PF16558.5 EGR30407.1 - 0.075 13.3 0.4 0.15 12.3 0.4 1.5 1 0 0 1 1 1 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A DUF1759 PF03564.15 EGR30408.1 - 0.039 13.9 0.0 0.06 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1759) DUF1759 PF03564.15 EGR30409.1 - 0.061 13.3 0.1 0.23 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1759) Rhodanese PF00581.20 EGR30410.1 - 7.1e-24 84.4 0.0 5.7e-15 55.7 0.0 3.5 3 1 0 3 3 3 2 Rhodanese-like domain Lactamase_B PF00753.27 EGR30410.1 - 1.9e-11 44.3 0.0 3.3e-11 43.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF442 PF04273.13 EGR30410.1 - 0.073 13.1 0.0 0.4 10.8 0.0 2.0 2 0 0 2 2 2 0 Putative phosphatase (DUF442) RIH_assoc PF08454.11 EGR30411.1 - 1.9e-30 104.7 4.3 1.9e-30 104.7 4.3 12.5 12 2 2 14 14 14 2 RyR and IP3R Homology associated MIR PF02815.19 EGR30411.1 - 3.4e-10 40.1 0.8 3.4e-10 40.1 0.8 3.7 3 0 0 3 3 3 2 MIR domain Ins145_P3_rec PF08709.11 EGR30411.1 - 4.1e-10 39.2 6.6 1.3e-09 37.6 6.6 1.9 1 1 0 1 1 1 1 Inositol 1,4,5-trisphosphate/ryanodine receptor RYDR_ITPR PF01365.21 EGR30411.1 - 5.9e-08 32.4 11.3 5.9e-08 32.4 11.3 7.9 6 2 0 6 6 6 2 RIH domain Ion_trans PF00520.31 EGR30411.1 - 5.2e-05 22.6 38.7 5.2e-05 22.6 38.7 3.7 3 1 0 3 3 3 1 Ion transport protein UPRTase PF14681.6 EGR30412.1 - 4.4e-63 212.5 0.0 5.2e-63 212.2 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EGR30412.1 - 3.9e-06 26.5 0.0 6.5e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Globin PF00042.22 EGR30412.1 - 0.1 13.2 0.0 2.8 8.5 0.0 3.0 4 0 0 4 4 4 0 Globin Peptidase_S9_N PF02897.15 EGR30412.1 - 0.1 11.4 0.1 0.16 10.8 0.1 1.4 1 1 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Band_7 PF01145.25 EGR30413.1 - 1e-22 81.0 1.1 1.5e-22 80.5 1.1 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EGR30413.1 - 0.00067 18.8 1.4 0.00092 18.4 1.4 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial RcpB PF16971.5 EGR30413.1 - 0.0016 18.3 9.3 0.0018 18.2 4.1 2.1 1 1 1 2 2 2 1 Rough colony protein B, tight adherence - tad - subunit SPG4 PF17325.2 EGR30413.1 - 0.037 15.1 0.8 0.069 14.2 0.8 1.6 1 0 0 1 1 1 0 Stationary phase protein 4 Band_7_1 PF13421.6 EGR30413.1 - 0.051 13.3 0.3 0.097 12.4 0.3 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Myb_Cef PF11831.8 EGR30414.1 - 4.3e-13 49.4 0.1 4.9e-13 49.2 0.1 1.0 1 0 0 1 1 1 1 pre-mRNA splicing factor component Myb_DNA-bind_6 PF13921.6 EGR30415.1 - 3.5e-22 78.4 7.9 1.6e-13 50.6 4.4 3.7 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGR30415.1 - 1.5e-20 73.1 13.7 1.1e-11 44.7 1.5 3.5 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_Cef PF11831.8 EGR30415.1 - 1.4e-06 28.1 11.5 1.4e-06 28.1 11.5 3.6 3 1 0 3 3 3 1 pre-mRNA splicing factor component Rap1_C PF11626.8 EGR30415.1 - 0.0053 16.8 0.6 0.23 11.6 0.1 2.9 2 0 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 EGR30415.1 - 0.04 14.1 0.7 0.13 12.5 0.5 2.0 1 1 0 1 1 1 0 SANT/Myb-like domain of DAMP1 ComC PF03047.14 EGR30415.1 - 8.1 6.4 9.0 1.5 8.7 0.4 3.4 3 0 0 3 3 3 0 COMC family ECH_1 PF00378.20 EGR30416.1 - 6.2e-30 104.3 1.4 7.3e-30 104.1 1.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGR30416.1 - 1.1e-09 38.3 0.1 2e-09 37.4 0.1 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Pkinase PF00069.25 EGR30417.1 - 6.6e-75 251.9 0.1 6.6e-75 251.9 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30417.1 - 2.3e-33 115.6 0.1 1.5e-32 112.9 0.1 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR30417.1 - 0.00026 20.4 0.1 0.00075 18.9 0.1 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR30417.1 - 0.0018 18.2 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family SAPS PF04499.15 EGR30418.1 - 9.2e-10 37.9 23.4 2e-08 33.5 3.9 6.0 2 2 3 5 5 5 2 SIT4 phosphatase-associated protein VPS13_C PF16909.5 EGR30419.1 - 6.5e-49 166.1 14.2 7e-49 166.0 6.1 2.7 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 EGR30419.1 - 0.0032 17.8 0.0 0.0098 16.2 0.0 1.8 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain PADR1 PF08063.12 EGR30422.1 - 7.5e-17 60.9 2.3 1e-16 60.4 2.3 1.2 1 0 0 1 1 1 1 PADR1 (NUC008) domain TF_Zn_Ribbon PF08271.12 EGR30422.1 - 0.011 15.2 0.6 0.022 14.3 0.6 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding SAP PF02037.27 EGR30422.1 - 0.011 15.4 0.1 0.019 14.7 0.1 1.4 1 0 0 1 1 1 0 SAP domain zf-Dof PF02701.15 EGR30422.1 - 0.17 12.0 0.5 0.17 12.0 0.5 1.9 2 1 0 2 2 2 0 Dof domain, zinc finger Pkinase PF00069.25 EGR30423.1 - 7.5e-69 232.0 0.2 1.6e-68 231.0 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30423.1 - 1.1e-34 119.9 0.0 1.8e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR30423.1 - 1.2e-06 27.6 0.1 2.7e-06 26.4 0.1 1.9 1 1 0 1 1 1 1 Fungal protein kinase PH PF00169.29 EGR30423.1 - 0.0016 18.9 2.7 0.003 18.0 1.6 2.1 1 1 0 1 1 1 1 PH domain Kinase-like PF14531.6 EGR30423.1 - 0.0017 17.7 1.0 0.65 9.2 0.2 2.6 1 1 1 2 2 2 2 Kinase-like APH PF01636.23 EGR30423.1 - 0.003 17.5 0.0 0.015 15.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR30423.1 - 0.0098 15.3 0.5 0.03 13.7 0.5 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PglD_N PF17836.1 EGR30423.1 - 0.012 16.3 0.5 3.4 8.4 0.0 3.4 2 0 0 2 2 2 0 PglD N-terminal domain MORN PF02493.20 EGR30424.1 - 6e-60 195.7 81.9 1.4e-07 31.0 2.6 10.5 10 0 0 10 10 10 10 MORN repeat Peptidase_A3 PF02160.15 EGR30424.1 - 0.35 10.3 7.2 0.51 9.8 7.2 1.2 1 0 0 1 1 1 0 Cauliflower mosaic virus peptidase (A3) Presenilin PF01080.17 EGR30424.1 - 1.8 7.3 6.7 2.1 7.0 6.7 1.1 1 0 0 1 1 1 0 Presenilin UPF0242 PF06785.11 EGR30424.1 - 1.8 8.6 14.6 2.6 8.1 14.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Membralin PF09746.9 EGR30424.1 - 4.1 6.3 6.6 5.2 6.0 6.6 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF5613 PF18467.1 EGR30424.1 - 4.2 7.8 11.9 15 6.1 0.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5613) Mog1 PF04603.12 EGR30424.1 - 6.9 7.0 10.7 11 6.4 10.7 1.2 1 0 0 1 1 1 0 Ran-interacting Mog1 protein MT-A70 PF05063.14 EGR30425.1 - 3.8e-57 192.9 0.3 8.3e-57 191.8 0.3 1.6 1 0 0 1 1 1 1 MT-A70 Na_H_Exchanger PF00999.21 EGR30426.1 - 2.8e-46 158.1 30.1 3.7e-46 157.6 30.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family cNMP_binding PF00027.29 EGR30426.1 - 0.0077 16.3 0.0 0.024 14.7 0.0 1.8 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain DUF4203 PF13886.6 EGR30427.1 - 4.4e-34 117.9 38.2 5.8e-34 117.5 38.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) PHO4 PF01384.20 EGR30427.1 - 1.4 7.9 6.7 1.4 7.9 4.8 1.7 1 1 0 1 1 1 0 Phosphate transporter family EF-hand_6 PF13405.6 EGR30428.1 - 2.9e-11 42.3 0.6 0.00046 19.9 0.0 3.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EGR30428.1 - 2.6e-09 37.4 1.1 2.5e-05 24.6 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR30428.1 - 5.5e-06 25.5 4.0 0.087 12.4 0.0 4.3 4 1 0 4 4 4 3 EF hand DUF2420 PF10336.9 EGR30428.1 - 0.028 14.4 1.2 1 9.4 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF2420) Cornifin PF02389.15 EGR30429.1 - 1.6e-11 44.5 151.1 0.0013 18.9 47.0 5.5 2 1 4 6 6 6 5 Cornifin (SPRR) family Peptidase_M8 PF01457.16 EGR30430.1 - 1.6e-37 129.4 6.4 5.2e-33 114.5 0.1 2.3 1 1 1 2 2 2 2 Leishmanolysin VSP PF03302.13 EGR30430.1 - 2.4e-05 23.4 17.1 2.4e-05 23.4 17.1 2.3 1 1 0 2 2 2 1 Giardia variant-specific surface protein EGF_Tenascin PF18720.1 EGR30430.1 - 0.00012 22.1 7.9 0.00062 19.7 7.9 2.4 1 0 0 1 1 1 1 Tenascin EGF domain Peptidase_M8 PF01457.16 EGR30431.1 - 2.8e-36 125.3 5.4 3.8e-31 108.4 0.1 2.2 1 1 1 2 2 2 2 Leishmanolysin VSP PF03302.13 EGR30431.1 - 2e-05 23.7 15.2 2e-05 23.7 15.2 2.0 1 1 0 2 2 2 1 Giardia variant-specific surface protein EGF_Tenascin PF18720.1 EGR30431.1 - 0.16 12.1 15.8 0.035 14.2 11.1 2.5 2 0 0 2 2 2 0 Tenascin EGF domain FA_desaturase PF00487.24 EGR30432.1 - 1.7e-32 113.2 15.3 2e-32 113.0 15.3 1.0 1 0 0 1 1 1 1 Fatty acid desaturase DUF805 PF05656.14 EGR30432.1 - 6.1 7.3 9.1 53 4.3 9.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Cyt-b5 PF00173.28 EGR30433.1 - 4.1e-13 49.3 0.0 7.6e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain AAA_5 PF07728.14 EGR30434.1 - 4.1e-102 337.8 2.1 2.1e-21 76.4 0.0 8.2 7 1 1 8 8 7 7 AAA domain (dynein-related subfamily) ATP-grasp_2 PF08442.10 EGR30434.1 - 2.9e-46 157.6 2.4 2.9e-46 157.6 2.4 3.3 2 0 0 2 2 2 1 ATP-grasp domain AAA_3 PF07726.11 EGR30434.1 - 4.8e-24 84.7 0.0 1.2e-05 25.2 0.0 6.7 7 0 0 7 7 6 5 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EGR30434.1 - 6.1e-22 78.5 1.6 0.0033 17.9 0.1 7.1 5 1 0 5 5 5 5 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGR30434.1 - 5.9e-21 75.6 5.0 0.002 18.6 0.0 7.2 7 0 0 7 7 6 5 AAA ATPase domain AAA_7 PF12775.7 EGR30434.1 - 3e-20 72.5 1.1 0.00015 21.3 0.0 6.4 5 0 0 5 5 5 5 P-loop containing dynein motor region Sigma54_activat PF00158.26 EGR30434.1 - 3.6e-18 65.8 3.2 0.033 13.9 0.2 7.1 7 0 0 7 7 7 5 Sigma-54 interaction domain Ligase_CoA PF00549.19 EGR30434.1 - 5.5e-18 65.2 0.2 1.7e-17 63.7 0.2 1.9 1 0 0 1 1 1 1 CoA-ligase AAA_lid_5 PF17865.1 EGR30434.1 - 1e-16 60.9 0.1 1e-16 60.9 0.1 3.9 4 0 0 4 4 3 1 Midasin AAA lid domain AAA_lid_7 PF17867.1 EGR30434.1 - 2.8e-16 59.6 0.2 3.2e-13 49.8 0.4 3.4 3 0 0 3 3 2 1 Midasin AAA lid domain TsaE PF02367.17 EGR30434.1 - 5.2e-15 55.5 0.5 0.15 12.1 0.0 5.9 5 0 0 5 5 5 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EGR30434.1 - 9.3e-14 51.9 12.6 0.0054 17.0 0.0 7.5 7 1 0 7 7 5 4 AAA domain NACHT PF05729.12 EGR30434.1 - 1.6e-11 44.4 0.2 0.07 13.0 0.0 5.2 4 0 0 4 4 4 3 NACHT domain RsgA_GTPase PF03193.16 EGR30434.1 - 6.7e-11 42.4 14.7 0.0056 16.6 0.1 6.9 6 0 0 6 6 5 2 RsgA GTPase AAA_30 PF13604.6 EGR30434.1 - 1.7e-10 40.9 0.0 1.9 8.1 0.0 7.5 8 0 0 8 8 7 1 AAA domain RuvB_N PF05496.12 EGR30434.1 - 1.3e-09 38.0 0.8 4.6 7.0 0.0 7.1 7 1 0 7 7 7 1 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 EGR30434.1 - 2.1e-09 37.6 1.2 0.44 10.6 0.0 6.6 6 0 0 6 6 5 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 EGR30434.1 - 2.5e-09 36.9 0.3 2.2 7.6 0.0 6.9 7 0 0 7 7 6 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EGR30434.1 - 2.3e-08 34.4 12.3 0.16 12.4 0.0 7.8 8 0 0 8 8 5 2 RNA helicase IstB_IS21 PF01695.17 EGR30434.1 - 1.3e-07 31.6 0.0 0.11 12.2 0.0 5.5 5 0 0 5 5 5 1 IstB-like ATP binding protein T2SSE PF00437.20 EGR30434.1 - 2e-07 30.4 0.2 4.7 6.2 0.1 5.5 5 0 0 5 5 5 1 Type II/IV secretion system protein AAA_19 PF13245.6 EGR30434.1 - 2.2e-07 31.3 0.8 5.7 7.3 0.1 6.6 5 1 0 5 5 5 0 AAA domain AAA_29 PF13555.6 EGR30434.1 - 2.5e-07 30.3 1.3 3.7 7.3 0.0 5.5 5 0 0 5 5 5 1 P-loop containing region of AAA domain AAA_33 PF13671.6 EGR30434.1 - 7.2e-07 29.5 1.0 10 6.3 0.0 6.5 6 0 0 6 6 6 0 AAA domain AAA_28 PF13521.6 EGR30434.1 - 8e-06 26.2 0.2 1.1 9.5 0.0 6.3 5 0 0 5 5 5 1 AAA domain PduV-EutP PF10662.9 EGR30434.1 - 1.1e-05 25.2 7.3 0.19 11.5 0.0 5.1 5 0 0 5 5 4 2 Ethanolamine utilisation - propanediol utilisation AAA_25 PF13481.6 EGR30434.1 - 2e-05 24.3 0.1 1.8 8.1 0.0 4.4 4 0 0 4 4 4 2 AAA domain Viral_helicase1 PF01443.18 EGR30434.1 - 0.00022 21.1 10.8 0.32 10.7 0.0 6.6 6 1 1 7 7 5 1 Viral (Superfamily 1) RNA helicase ATP-synt_ab PF00006.25 EGR30434.1 - 0.00036 20.3 0.0 1.5 8.5 0.0 3.9 4 1 0 4 4 4 1 ATP synthase alpha/beta family, nucleotide-binding domain CPT PF07931.12 EGR30434.1 - 0.016 15.1 1.5 54 3.6 0.0 5.8 7 0 0 7 7 6 0 Chloramphenicol phosphotransferase-like protein ABC_tran PF00005.27 EGR30434.1 - 0.042 14.4 0.1 0.042 14.4 0.1 11.2 7 2 0 7 7 5 0 ABC transporter MMR_HSR1 PF01926.23 EGR30434.1 - 0.14 12.2 10.3 20 5.3 0.0 6.5 8 0 0 8 8 5 0 50S ribosome-binding GTPase AAA_18 PF13238.6 EGR30434.1 - 0.21 12.2 0.0 0.21 12.2 0.0 13.3 11 2 1 14 14 10 0 AAA domain Cytidylate_kin PF02224.18 EGR30434.1 - 0.38 10.4 7.8 1.7 8.4 0.0 5.1 4 0 0 4 4 3 0 Cytidylate kinase GPCR_chapero_1 PF11904.8 EGR30435.1 - 0.61 9.5 20.5 0.037 13.5 13.9 2.1 2 0 0 2 2 2 0 GPCR-chaperone Hid1 PF12722.7 EGR30435.1 - 3.8 5.5 25.5 6.1 4.8 25.5 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PFK PF00365.20 EGR30437.1 - 1.9e-10 40.5 0.0 2.6e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Phosphofructokinase Myb_DNA-binding PF00249.31 EGR30440.1 - 1.7e-31 108.1 5.5 2.7e-16 59.5 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGR30440.1 - 5.7e-22 77.7 3.6 1.4e-12 47.7 0.7 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGR30440.1 - 4e-08 33.1 0.4 9.7e-08 31.8 0.1 1.8 2 0 0 2 2 2 1 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EGR30440.1 - 0.0012 19.0 1.3 0.19 11.9 0.1 2.4 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 Sigma70_r4_2 PF08281.12 EGR30440.1 - 0.006 16.2 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Sigma-70, region 4 Myb_DNA-bind_4 PF13837.6 EGR30440.1 - 0.016 15.6 5.2 0.033 14.5 0.6 2.6 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain SLIDE PF09111.10 EGR30440.1 - 0.029 14.4 2.8 0.61 10.1 0.1 2.4 2 1 0 2 2 2 0 SLIDE DUF1539 PF07560.11 EGR30440.1 - 0.07 13.2 1.5 0.2 11.7 0.6 2.3 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1539) MORN PF02493.20 EGR30441.1 - 3e-57 187.2 80.4 2.1e-08 33.6 1.7 10.1 10 0 0 10 10 10 9 MORN repeat DUF5387 PF17361.2 EGR30441.1 - 3.9 7.1 8.6 0.11 12.2 1.5 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5387) Thioredoxin PF00085.20 EGR30442.1 - 8.8e-63 208.7 0.3 3.1e-30 104.2 0.0 4.0 3 1 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 EGR30442.1 - 3.4e-35 121.6 9.9 8.9e-26 90.9 5.4 3.3 2 1 1 3 3 3 3 Thioredoxin-like domain OST3_OST6 PF04756.13 EGR30442.1 - 1.2e-16 60.9 0.3 2.3e-07 30.5 0.0 3.6 3 1 1 4 4 4 3 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EGR30442.1 - 4.1e-10 39.8 3.2 0.024 14.9 0.0 4.6 3 2 0 3 3 3 3 Thioredoxin-like Thioredoxin_7 PF13899.6 EGR30442.1 - 7.3e-09 35.7 0.1 0.0065 16.6 0.0 3.3 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EGR30442.1 - 1.1e-08 35.5 3.9 0.00013 22.4 0.0 4.1 3 2 0 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.21 EGR30442.1 - 6.1e-08 32.6 1.3 0.0021 18.0 0.0 3.4 3 1 1 4 4 4 2 AhpC/TSA family ERp29_N PF07912.13 EGR30442.1 - 2.8e-07 30.7 6.0 0.0058 16.8 0.0 4.3 2 1 2 4 4 4 2 ERp29, N-terminal domain Redoxin PF08534.10 EGR30442.1 - 0.00037 20.2 0.7 1.1 9.0 0.0 3.0 3 1 0 3 3 3 2 Redoxin LAT PF15234.6 EGR30442.1 - 0.023 14.4 0.0 0.44 10.2 0.0 2.1 2 0 0 2 2 2 0 Linker for activation of T-cells Thioredoxin_4 PF13462.6 EGR30442.1 - 3.5 7.7 5.5 28 4.8 0.0 3.4 3 2 1 4 4 4 0 Thioredoxin adh_short PF00106.25 EGR30443.1 - 1.5e-52 177.9 0.0 2.5e-52 177.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGR30443.1 - 3e-36 125.2 0.0 3.9e-36 124.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGR30443.1 - 4.5e-10 39.7 0.0 7e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 KR domain SHIPPO-rpt PF07004.12 EGR30443.1 - 3.6e-07 30.8 24.9 0.22 12.5 0.2 5.9 6 0 0 6 6 6 3 Sperm-tail PG-rich repeat DUF1776 PF08643.10 EGR30443.1 - 0.007 15.8 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 EGR30443.1 - 0.017 14.2 0.2 0.049 12.8 0.1 1.7 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein MORN PF02493.20 EGR30444.1 - 1.6e-41 137.8 65.7 6.8e-06 25.7 2.6 10.0 10 0 0 10 10 10 9 MORN repeat IQ PF00612.27 EGR30444.1 - 0.047 13.5 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif Transglut_i_TM PF14400.6 EGR30444.1 - 0.38 10.8 4.0 0.27 11.3 0.8 2.2 2 0 0 2 2 2 0 Inactive transglutaminase fused to 7 transmembrane helices DEAD PF00270.29 EGR30445.1 - 6e-28 97.8 0.2 3.2e-27 95.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF2252 PF10009.9 EGR30445.1 - 1.2 8.2 10.9 1.5 7.8 9.6 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) Helicase_C PF00271.31 EGR30446.1 - 3.2e-25 88.6 2.4 5.8e-25 87.8 0.0 2.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain Latarcin PF10279.9 EGR30446.1 - 0.00012 22.4 0.0 12 6.4 5.3 3.8 3 2 0 3 3 3 2 Latarcin precursor Peptidase_M24 PF00557.24 EGR30446.1 - 0.14 11.8 0.1 0.63 9.7 0.1 2.0 2 0 0 2 2 2 0 Metallopeptidase family M24 YqzH PF14164.6 EGR30446.1 - 0.14 12.2 4.5 8.9 6.5 1.8 3.2 2 0 0 2 2 2 0 YqzH-like protein tRNA-synt_His PF13393.6 EGR30446.1 - 0.8 8.9 6.1 5.8 6.1 4.7 2.3 1 1 1 2 2 2 0 Histidyl-tRNA synthetase PhoLip_ATPase_C PF16212.5 EGR30447.1 - 4.6e-20 72.4 11.8 4.6e-20 72.4 11.8 3.1 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGR30447.1 - 4.1e-18 64.8 7.7 4.1e-18 64.8 7.7 3.2 2 1 1 3 3 3 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGR30447.1 - 6.2e-13 48.6 0.8 1.3e-11 44.4 0.3 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGR30447.1 - 6.4e-11 42.9 0.1 1.5e-05 25.4 0.1 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGR30447.1 - 0.00022 20.8 0.0 0.00049 19.7 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Fer4_14 PF13394.6 EGR30447.1 - 0.045 13.9 2.9 0.08 13.1 0.8 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain UL41A PF17591.2 EGR30447.1 - 0.48 10.6 5.7 0.79 9.9 1.2 3.5 3 1 1 4 4 4 0 Herpesvirus UL41A Sortilin-Vps10 PF15902.5 EGR30448.1 - 9.8e-46 156.4 16.2 5.2e-42 144.2 10.9 2.3 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, PSII_BNR PF14870.6 EGR30448.1 - 0.00022 20.6 1.2 0.0008 18.8 0.5 2.2 2 0 0 2 2 2 1 Photosynthesis system II assembly factor YCF48 BNR_6 PF15899.5 EGR30448.1 - 0.00076 19.3 4.8 0.099 12.7 0.1 3.9 3 0 0 3 3 3 2 BNR-Asp box repeat BNR PF02012.20 EGR30448.1 - 0.18 11.9 19.0 0.56 10.4 0.4 5.9 6 1 0 6 6 6 0 BNR/Asp-box repeat Rubis-subs-bind PF09273.11 EGR30449.1 - 1.3e-11 45.3 0.0 1.3e-11 45.3 0.0 2.5 2 1 0 2 2 2 1 Rubisco LSMT substrate-binding AI-2E_transport PF01594.16 EGR30449.1 - 8.4 5.4 12.4 0.67 9.0 6.8 2.0 2 0 0 2 2 2 0 AI-2E family transporter DRE2_N PF16803.5 EGR30450.1 - 0.0018 18.5 0.5 0.01 16.1 0.3 2.3 1 1 1 2 2 2 1 Fe-S cluster assembly protein DRE2 N-terminus HSP20 PF00011.21 EGR30450.1 - 0.019 15.1 0.0 0.061 13.5 0.0 1.9 1 0 0 1 1 1 0 Hsp20/alpha crystallin family Exonuc_VII_L PF02601.15 EGR30451.1 - 6.3 6.3 6.3 17 4.9 6.3 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit Mt_ATP-synt_D PF05873.12 EGR30452.1 - 7.1e-07 29.2 2.8 1e-06 28.7 1.8 1.7 1 1 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) Acetyltransf_11 PF13720.6 EGR30452.1 - 0.034 14.6 0.1 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 XH PF03469.14 EGR30452.1 - 0.055 13.4 3.2 0.15 11.9 3.2 1.9 1 1 0 1 1 1 0 XH domain DUF4485 PF14846.6 EGR30452.1 - 0.32 11.1 2.6 0.33 11.0 0.3 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4485) CUTL PF16557.5 EGR30452.1 - 1.4 9.1 7.2 0.41 10.8 3.8 1.8 2 0 0 2 2 2 0 CUT1-like DNA-binding domain of SATB Myb_DNA-binding PF00249.31 EGR30453.1 - 2.1e-25 88.7 4.8 3.8e-14 52.6 2.2 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGR30453.1 - 1.8e-21 76.1 6.5 4.7e-16 58.8 1.9 2.3 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EGR30453.1 - 0.00034 20.6 0.3 0.44 10.6 0.0 2.1 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EGR30453.1 - 0.00038 20.3 3.9 0.0029 17.4 0.7 2.1 1 1 1 2 2 2 1 Myb DNA-binding like Rap1_C PF11626.8 EGR30453.1 - 0.0008 19.5 0.0 1.3 9.1 0.0 2.2 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SWIB PF02201.18 EGR30453.1 - 0.028 14.3 0.7 0.052 13.4 0.7 1.4 1 0 0 1 1 1 0 SWIB/MDM2 domain DnaA_N PF11638.8 EGR30453.1 - 0.16 11.8 2.0 6.9 6.5 0.0 2.8 3 0 0 3 3 3 0 DnaA N-terminal domain SPT16 PF08644.11 EGR30454.1 - 1.2e-46 158.7 7.2 1.2e-46 158.7 7.2 4.1 4 1 0 4 4 4 1 FACT complex subunit (SPT16/CDC68) Peptidase_M24 PF00557.24 EGR30454.1 - 7.7e-31 107.4 0.0 1.7e-30 106.3 0.0 1.6 1 0 0 1 1 1 1 Metallopeptidase family M24 FACT-Spt16_Nlob PF14826.6 EGR30454.1 - 4.8e-29 101.2 5.1 4.8e-29 101.2 5.1 3.3 4 0 0 4 4 4 1 FACT complex subunit SPT16 N-terminal lobe domain Rtt106 PF08512.12 EGR30454.1 - 3.7e-13 49.7 1.8 1.8e-12 47.5 0.1 3.0 3 0 0 3 3 3 1 Histone chaperone Rttp106-like CHZ PF09649.10 EGR30454.1 - 0.0011 18.4 0.5 0.0041 16.5 0.5 2.1 1 0 0 1 1 1 1 Histone chaperone domain CHZ CactinC_cactus PF09732.9 EGR30454.1 - 0.0062 16.5 0.4 0.042 13.8 0.2 2.5 2 0 0 2 2 2 1 Cactus-binding C-terminus of cactin protein Polysacc_deac_2 PF04748.13 EGR30454.1 - 0.048 12.8 0.0 0.17 11.0 0.0 1.9 2 0 0 2 2 2 0 Divergent polysaccharide deacetylase 60KD_IMP PF02096.20 EGR30454.1 - 6.1 6.7 6.1 20 5.1 6.1 1.9 1 0 0 1 1 1 0 60Kd inner membrane protein Ras PF00071.22 EGR30455.1 - 2.8e-58 196.1 2.1 3.3e-58 195.9 2.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR30455.1 - 2.3e-30 105.3 0.7 3.6e-30 104.6 0.7 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR30455.1 - 6.3e-15 55.1 0.8 7.4e-15 54.8 0.8 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGR30455.1 - 7.7e-06 25.9 0.2 0.0042 17.0 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EGR30455.1 - 0.00047 19.7 0.6 0.0014 18.1 0.6 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.17 EGR30455.1 - 0.00076 19.3 0.7 0.0025 17.6 0.0 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein SRPRB PF09439.10 EGR30455.1 - 0.00076 19.0 0.2 0.0017 17.8 0.1 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGR30455.1 - 0.0009 18.7 0.9 0.0024 17.3 0.9 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGR30455.1 - 0.0015 18.1 1.0 0.0052 16.3 0.2 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain DUF2291 PF10054.9 EGR30455.1 - 0.02 14.6 0.3 0.044 13.5 0.2 1.5 1 1 0 1 1 1 0 Predicted periplasmic lipoprotein (DUF2291) AAA_5 PF07728.14 EGR30455.1 - 0.031 14.3 0.0 0.041 13.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) CbiA PF01656.23 EGR30455.1 - 0.085 12.9 0.1 0.17 11.9 0.1 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 EGR30455.1 - 0.17 11.6 5.1 3 7.5 5.1 2.3 1 1 0 1 1 1 0 AAA domain Mpp10 PF04006.12 EGR30456.1 - 0.0064 15.0 42.5 0.0073 14.8 42.5 1.0 1 0 0 1 1 1 1 Mpp10 protein BUD22 PF09073.10 EGR30456.1 - 0.017 14.4 38.1 0.022 14.1 38.1 1.1 1 0 0 1 1 1 0 BUD22 Paf1 PF03985.13 EGR30456.1 - 0.029 13.4 40.9 0.035 13.1 40.9 1.1 1 0 0 1 1 1 0 Paf1 V_ATPase_I PF01496.19 EGR30456.1 - 0.067 11.1 21.2 0.077 10.9 21.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.16 EGR30456.1 - 0.1 12.7 12.1 0.12 12.4 12.1 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 EGR30456.1 - 0.1 11.8 18.0 0.12 11.6 18.0 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter Vfa1 PF08432.10 EGR30456.1 - 0.12 12.6 31.2 0.19 12.0 31.2 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.12 EGR30456.1 - 0.13 10.4 44.4 0.15 10.2 44.4 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 EGR30456.1 - 0.19 10.4 28.3 0.24 10.1 28.3 1.0 1 0 0 1 1 1 0 Presenilin BORG_CEP PF14957.6 EGR30456.1 - 0.19 12.9 12.7 0.2 12.8 12.7 1.1 1 0 0 1 1 1 0 Cdc42 effector NPR3 PF03666.13 EGR30456.1 - 0.32 9.8 24.0 0.36 9.6 24.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Cwf_Cwc_15 PF04889.12 EGR30456.1 - 0.34 10.6 38.2 0.43 10.3 38.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Spore_coat_CotO PF14153.6 EGR30456.1 - 0.38 10.7 37.5 0.48 10.3 37.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO MID_MedPIWI PF18296.1 EGR30456.1 - 0.56 9.9 7.4 0.75 9.5 7.4 1.4 1 0 0 1 1 1 0 MID domain of medPIWI DUF5427 PF10310.9 EGR30456.1 - 0.89 8.4 26.5 0.99 8.3 26.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) SLC12 PF03522.15 EGR30456.1 - 2 7.3 21.9 2.3 7.1 21.9 1.0 1 0 0 1 1 1 0 Solute carrier family 12 SDA1 PF05285.12 EGR30456.1 - 2 7.7 49.0 2.5 7.4 49.0 1.1 1 0 0 1 1 1 0 SDA1 Raftlin PF15250.6 EGR30456.1 - 2.1 7.0 18.0 2.3 6.9 18.0 1.0 1 0 0 1 1 1 0 Raftlin ALMT PF11744.8 EGR30456.1 - 2.3 7.0 22.5 2.4 6.9 22.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2151 PF10221.9 EGR30456.1 - 2.4 6.7 20.5 2.7 6.5 20.5 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator DUF2828 PF11443.8 EGR30456.1 - 2.7 6.0 20.0 3.6 5.5 20.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) RR_TM4-6 PF06459.12 EGR30456.1 - 2.7 7.7 35.1 3.6 7.3 35.1 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TT_ORF1 PF02956.14 EGR30456.1 - 2.7 6.5 9.0 3 6.4 9.0 1.0 1 0 0 1 1 1 0 TT viral orf 1 TFIIA PF03153.13 EGR30456.1 - 2.9 7.8 28.1 3.4 7.6 28.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4045 PF13254.6 EGR30456.1 - 2.9 7.4 23.8 3.3 7.3 23.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) CDC45 PF02724.14 EGR30456.1 - 3.3 5.9 36.0 4.1 5.6 36.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4246 PF14033.6 EGR30456.1 - 3.3 6.7 18.1 4.6 6.2 18.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4246) FAM60A PF15396.6 EGR30456.1 - 3.5 7.6 19.7 4.3 7.3 19.7 1.1 1 0 0 1 1 1 0 Protein Family FAM60A XRN_M PF17846.1 EGR30456.1 - 3.6 6.4 22.6 4.1 6.3 22.6 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Hid1 PF12722.7 EGR30456.1 - 3.9 5.5 21.9 4.4 5.3 21.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Caldesmon PF02029.15 EGR30456.1 - 4.3 6.0 47.3 5 5.8 47.3 1.0 1 0 0 1 1 1 0 Caldesmon Velvet PF11754.8 EGR30456.1 - 4.9 7.0 9.0 5.7 6.8 9.0 1.0 1 0 0 1 1 1 0 Velvet factor CCSAP PF15748.5 EGR30456.1 - 5.7 7.0 26.6 7.1 6.7 26.6 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated MDM1 PF15501.6 EGR30456.1 - 6 5.9 31.0 7.1 5.7 31.0 1.1 1 0 0 1 1 1 0 Nuclear protein MDM1 O-antigen_lig PF13425.6 EGR30456.1 - 6 5.5 17.6 8.7 5.0 17.6 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Gti1_Pac2 PF09729.9 EGR30456.1 - 6.1 6.9 19.9 9.3 6.3 19.9 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Endostatin PF06482.11 EGR30456.1 - 7.1 6.0 12.9 8.4 5.8 12.9 1.0 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin FGF-BP1 PF06473.12 EGR30456.1 - 8.3 6.2 25.5 10 5.9 25.5 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) TTL PF03133.15 EGR30458.1 - 6.5e-36 124.0 5.9 6.5e-36 124.0 5.9 2.5 3 0 0 3 3 3 1 Tubulin-tyrosine ligase family LRR_4 PF12799.7 EGR30458.1 - 0.00043 20.6 1.7 0.00043 20.6 1.7 5.2 3 2 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGR30458.1 - 0.005 16.6 10.8 0.35 10.7 0.6 2.9 2 0 0 2 2 2 2 Leucine rich repeat EF-hand_6 PF13405.6 EGR30461.1 - 4.8e-10 38.5 13.7 0.00011 21.8 0.1 4.5 3 1 1 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EGR30461.1 - 1.9e-09 37.8 11.4 4.7e-06 27.0 4.6 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR30461.1 - 8e-09 34.4 11.9 0.0018 17.7 0.1 3.9 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EGR30461.1 - 7.7e-06 25.7 6.6 0.21 11.4 1.5 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 EGR30461.1 - 0.012 15.9 0.2 4.7 7.6 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain SPARC_Ca_bdg PF10591.9 EGR30461.1 - 0.14 12.5 4.1 5 7.5 0.0 2.5 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Sterile PF03015.19 EGR30461.1 - 2.4 8.5 4.8 7.4 6.9 0.4 2.4 3 0 0 3 3 3 0 Male sterility protein DUF5109 PF17134.4 EGR30462.1 - 0.097 12.6 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5109) HTH_50 PF18024.1 EGR30463.1 - 0.12 12.0 0.4 0.78 9.4 0.1 2.5 2 0 0 2 2 2 0 Helix-turn-helix domain YtxH PF12732.7 EGR30463.1 - 2 9.0 17.6 20 5.8 4.2 5.2 1 1 1 2 2 2 0 YtxH-like protein Aldedh PF00171.22 EGR30464.1 - 4.7e-84 282.5 0.0 5.9e-84 282.2 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGR30464.1 - 0.00059 19.0 0.0 0.00082 18.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) SAS4 PF15460.6 EGR30464.1 - 1.2 9.2 4.2 1.4 9.1 0.9 2.3 2 0 0 2 2 2 0 Something about silencing, SAS, complex subunit 4 Abhydrolase_3 PF07859.13 EGR30465.1 - 2.9e-35 122.0 0.0 3.6e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGR30465.1 - 2.4e-09 36.5 2.7 3.6e-09 36.0 2.6 1.3 1 1 0 1 1 1 1 Steryl acetyl hydrolase Hydrolase_4 PF12146.8 EGR30465.1 - 0.023 13.9 0.0 0.087 12.1 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Rtt106 PF08512.12 EGR30466.1 - 6.6e-20 71.3 1.0 1.7e-19 70.0 0.8 1.8 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SSrecog PF03531.14 EGR30466.1 - 9.7e-15 54.2 0.8 3e-14 52.7 0.1 2.3 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) POB3_N PF17292.2 EGR30466.1 - 0.0066 16.8 0.0 0.019 15.4 0.0 1.9 1 0 0 1 1 1 1 POB3-like N-terminal PH domain Cwf_Cwc_15 PF04889.12 EGR30466.1 - 3.3 7.4 32.5 0.036 13.8 20.2 2.5 3 0 0 3 3 3 0 Cwf15/Cwc15 cell cycle control protein Peptidase_M8 PF01457.16 EGR30467.1 - 1.3e-20 73.6 19.7 1.1e-18 67.3 1.5 2.6 2 1 1 3 3 3 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR30467.1 - 9.3e-07 28.8 11.1 9.3e-07 28.8 11.1 4.0 3 0 0 3 3 3 1 Tenascin EGF domain Furin-like_2 PF15913.5 EGR30467.1 - 0.0054 16.9 14.7 0.0054 16.9 14.7 6.2 2 1 4 6 6 6 1 Furin-like repeat, cysteine-rich EGF_2 PF07974.13 EGR30467.1 - 0.0082 16.5 14.1 0.0082 16.5 14.1 8.6 6 3 1 7 7 7 1 EGF-like domain Suv3_C_1 PF18147.1 EGR30467.1 - 0.12 12.2 0.1 0.23 11.4 0.1 1.4 1 0 0 1 1 1 0 Suv3 C-terminal domain 1 DEAD PF00270.29 EGR30468.1 - 3.5e-40 137.6 0.7 1.3e-39 135.8 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR30468.1 - 2.6e-25 88.9 0.3 2.6e-25 88.9 0.3 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGR30468.1 - 1.5e-06 28.3 0.2 3.4e-06 27.2 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ERCC3_RAD25_C PF16203.5 EGR30468.1 - 6.8e-06 25.5 1.7 1.3e-05 24.5 1.7 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EGR30468.1 - 1.6e-05 25.0 0.0 1.6e-05 25.0 0.0 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGR30468.1 - 0.0011 19.3 0.0 0.003 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain SH2 PF00017.24 EGR30468.1 - 0.12 12.5 0.1 2.3 8.4 0.0 2.8 3 0 0 3 3 3 0 SH2 domain Peptidase_M8 PF01457.16 EGR30469.1 - 1e-36 126.8 12.5 6.9e-31 107.5 0.3 3.6 2 1 1 3 3 3 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR30469.1 - 5.4e-08 32.7 8.5 5.4e-08 32.7 8.5 5.4 5 0 0 5 5 5 1 Tenascin EGF domain VSP PF03302.13 EGR30469.1 - 9e-05 21.5 156.7 0.00038 19.4 28.2 6.7 2 1 5 7 7 7 6 Giardia variant-specific surface protein cEGF PF12662.7 EGR30469.1 - 0.034 14.1 0.7 0.034 14.1 0.7 10.6 11 1 0 11 11 11 0 Complement Clr-like EGF-like Crystall_3 PF08964.10 EGR30471.1 - 0.062 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Beta/Gamma crystallin Myb_DNA-binding PF00249.31 EGR30472.1 - 1.4e-17 63.6 6.0 7e-12 45.4 2.4 3.2 2 1 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGR30472.1 - 2.5e-14 53.2 5.7 2.4e-13 50.1 1.4 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Rap1_C PF11626.8 EGR30472.1 - 0.00073 19.6 0.0 1.1 9.4 0.0 2.2 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain tRNA-synt_2 PF00152.20 EGR30475.1 - 1e-52 179.2 7.5 4.4e-42 144.3 0.2 2.9 2 1 1 3 3 3 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGR30475.1 - 2.1e-10 40.4 0.1 4e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGR30475.1 - 0.0013 18.2 0.0 0.0034 16.9 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) DUF1845 PF08900.11 EGR30475.1 - 0.015 15.1 0.2 0.029 14.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) PBECR1 PF18809.1 EGR30475.1 - 3.2 8.5 6.1 0.79 10.4 0.9 2.5 3 0 0 3 3 3 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 FA_desaturase PF00487.24 EGR30476.1 - 1.1e-07 32.0 8.9 3.6e-07 30.3 8.9 1.6 1 1 0 1 1 1 1 Fatty acid desaturase PhoLip_ATPase_C PF16212.5 EGR30477.1 - 2.4e-53 181.4 28.2 2.4e-53 181.4 28.2 2.7 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGR30477.1 - 1.9e-21 75.5 5.3 1.9e-21 75.5 5.3 3.4 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EGR30477.1 - 8.8e-14 51.4 2.0 2.1e-13 50.2 0.1 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGR30477.1 - 6.1e-11 43.0 0.4 2.4e-05 24.8 0.4 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGR30477.1 - 2e-09 37.4 0.2 6.2e-09 35.8 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGR30477.1 - 1e-05 25.4 2.7 1e-05 25.4 2.7 2.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase E1_4HB PF16191.5 EGR30477.1 - 0.1 12.8 0.1 0.46 10.7 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 four-helix bundle ISP1_C PF18161.1 EGR30477.1 - 0.22 11.5 5.9 0.055 13.5 1.7 2.3 2 0 0 2 2 2 0 ISP1 C-terminal Ribosomal_S27e PF01667.17 EGR30478.1 - 4.5e-23 80.7 4.4 5.5e-23 80.4 4.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 EGR30478.1 - 0.0018 17.7 0.5 0.0028 17.2 0.5 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Vps35 PF03635.17 EGR30479.1 - 2e-202 674.7 46.7 2.6e-202 674.2 46.7 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Taxilin PF09728.9 EGR30479.1 - 0.001 18.4 1.9 0.002 17.4 1.9 1.4 1 0 0 1 1 1 1 Myosin-like coiled-coil protein U3snoRNP10 PF12397.8 EGR30479.1 - 0.97 9.8 9.7 1 9.7 0.3 3.1 3 1 0 3 3 3 0 U3 small nucleolar RNA-associated protein 10 PALP PF00291.25 EGR30481.1 - 6e-74 249.1 0.0 7e-74 248.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EGR30481.1 - 9e-13 47.8 0.0 2.1e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 C-terminal regulatory domain of Threonine dehydratase LIAS_N PF16881.5 EGR30481.1 - 0.049 14.0 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of lipoyl synthase of Radical_SAM family PDEase_I PF00233.19 EGR30482.1 - 4.8e-59 200.0 7.4 7.2e-59 199.4 7.4 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 EGR30482.1 - 0.061 13.6 0.1 0.15 12.3 0.1 1.7 1 0 0 1 1 1 0 HD domain Ribonuclease_T2 PF00445.18 EGR30483.1 - 1.9e-39 135.8 5.6 2.5e-39 135.4 5.6 1.2 1 0 0 1 1 1 1 Ribonuclease T2 family PROCN PF08083.11 EGR30484.1 - 1.6e-228 758.3 8.3 1.6e-228 758.3 8.3 1.7 2 0 0 2 2 2 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EGR30484.1 - 5.9e-124 412.2 0.6 1.2e-123 411.2 0.6 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EGR30484.1 - 1.5e-88 294.8 4.0 4.5e-88 293.2 4.0 1.9 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EGR30484.1 - 1.7e-85 284.6 4.5 5.1e-85 283.0 4.5 1.9 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EGR30484.1 - 1.3e-71 238.9 0.0 2.8e-71 237.8 0.0 1.6 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 RRM_4 PF10598.9 EGR30484.1 - 2.5e-47 159.1 0.7 1.1e-46 157.1 0.7 2.2 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 PROCT PF08084.11 EGR30484.1 - 3.4e-46 156.2 0.4 9.7e-46 154.7 0.4 1.9 1 0 0 1 1 1 1 PROCT (NUC072) domain JAB PF01398.21 EGR30484.1 - 8.6e-05 22.5 0.0 0.0022 18.0 0.0 2.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Helicase_C PF00271.31 EGR30485.1 - 1.4e-18 67.3 1.2 3.6e-17 62.7 0.1 3.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EGR30485.1 - 2.9e-18 66.0 0.0 8.1e-18 64.6 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EGR30485.1 - 6.7e-09 36.0 0.6 2.3e-08 34.3 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) DEAD PF00270.29 EGR30485.1 - 8.4e-09 35.4 2.8 2.3e-08 34.0 0.3 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_19 PF13245.6 EGR30485.1 - 0.00039 20.8 0.0 0.00077 19.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGR30485.1 - 0.13 12.6 0.2 0.54 10.5 0.2 2.0 1 1 0 1 1 1 0 AAA domain IBN_N PF03810.19 EGR30486.1 - 9.2e-09 35.1 3.1 9.2e-09 35.1 3.1 3.1 2 0 0 2 2 2 1 Importin-beta N-terminal domain Drc1-Sld2 PF11719.8 EGR30486.1 - 2.4 7.6 6.9 3.8 7.0 6.9 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein TFIIF_alpha PF05793.12 EGR30486.1 - 4.5 5.7 9.8 6.9 5.1 9.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DAO PF01266.24 EGR30487.1 - 5e-14 52.7 0.0 3.6e-08 33.4 0.4 2.0 1 1 1 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 EGR30487.1 - 2.7e-07 30.1 0.1 3.9e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EGR30487.1 - 1.5e-05 24.3 0.1 2e-05 23.9 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGR30487.1 - 2.6e-05 24.3 0.4 5.1e-05 23.4 0.4 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGR30487.1 - 0.00041 19.2 0.0 0.00057 18.7 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein MCRA PF06100.11 EGR30487.1 - 0.0019 17.1 0.0 0.0019 17.0 0.0 1.1 1 0 0 1 1 1 1 MCRA family Lycopene_cycl PF05834.12 EGR30487.1 - 0.0037 16.4 0.0 0.005 15.9 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 EGR30487.1 - 0.005 16.1 0.0 0.0053 16.0 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGR30487.1 - 0.0066 15.7 0.0 0.0067 15.7 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGR30487.1 - 0.019 15.5 0.0 0.041 14.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGR30487.1 - 0.028 13.7 0.3 0.041 13.1 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Mqo PF06039.15 EGR30487.1 - 0.028 13.0 0.1 0.15 10.5 0.0 1.8 2 0 0 2 2 2 0 Malate:quinone oxidoreductase (Mqo) FAD_oxidored PF12831.7 EGR30487.1 - 0.071 12.4 0.0 0.087 12.2 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGR30487.1 - 0.12 12.3 0.1 0.2 11.7 0.1 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding Sugar_tr PF00083.24 EGR30488.1 - 3.4e-27 95.4 9.5 6.5e-27 94.5 9.5 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGR30488.1 - 5.8e-14 51.8 0.3 7.8e-14 51.4 0.3 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF1282 PF06930.12 EGR30488.1 - 0.055 13.2 5.8 1 9.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1282) TraL PF07178.11 EGR30488.1 - 0.41 11.1 2.7 4 8.0 0.0 3.2 2 1 1 3 3 3 0 TraL protein MFS_2 PF13347.6 EGR30488.1 - 0.49 8.9 12.1 0.015 13.9 4.8 2.0 3 0 0 3 3 3 0 MFS/sugar transport protein MORN PF02493.20 EGR30489.1 - 1.9e-63 206.7 109.0 2.4e-07 30.2 0.9 15.1 15 0 0 15 15 15 14 MORN repeat DUF2158 PF09926.9 EGR30489.1 - 0.15 11.8 3.3 2.1 8.2 0.1 3.1 2 1 0 2 2 2 0 Uncharacterized small protein (DUF2158) Pkinase PF00069.25 EGR30490.1 - 3.5e-58 197.0 4.8 3.5e-58 197.0 4.8 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30490.1 - 3e-31 108.6 0.9 3e-31 108.6 0.9 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR30490.1 - 1.9e-06 27.4 0.0 1.9e-06 27.4 0.0 2.2 2 1 1 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 EGR30490.1 - 2.7e-05 23.2 6.6 8.3e-05 21.5 6.6 1.9 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR30490.1 - 0.0023 17.9 0.0 0.0048 16.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR30490.1 - 0.0048 16.3 0.2 0.0048 16.3 0.2 2.1 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3221 PF11518.8 EGR30490.1 - 2 8.8 10.0 0.39 11.1 0.2 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3221) BH4 PF02180.17 EGR30490.1 - 3.6 7.5 5.1 5.4 6.9 1.0 3.0 2 0 0 2 2 2 0 Bcl-2 homology region 4 Peptidase_C2 PF00648.21 EGR30491.1 - 1.2e-60 205.1 0.2 1.6e-60 204.6 0.2 1.1 1 0 0 1 1 1 1 Calpain family cysteine protease DJ-1_PfpI PF01965.24 EGR30492.1 - 7.7e-36 123.4 0.0 8.7e-36 123.2 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 EGR30492.1 - 6.7e-05 22.7 0.0 7.5e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGR30492.1 - 0.00048 19.9 0.0 0.00075 19.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.14 EGR30492.1 - 0.11 12.0 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain AAA PF00004.29 EGR30493.1 - 2.6e-42 144.4 0.0 5.6e-42 143.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGR30493.1 - 2.5e-06 27.5 0.0 0.00025 21.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 EGR30493.1 - 2.8e-06 27.2 0.0 5.3e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGR30493.1 - 4.6e-06 27.1 0.0 0.00075 19.9 0.0 2.7 2 1 0 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 EGR30493.1 - 4e-05 23.6 0.0 0.00024 21.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EGR30493.1 - 6.9e-05 22.2 0.0 0.0002 20.7 0.0 1.5 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 EGR30493.1 - 0.00011 22.5 0.8 0.059 13.6 0.1 2.8 2 1 1 3 3 2 1 AAA domain ATPase PF06745.13 EGR30493.1 - 0.00014 21.3 0.9 0.33 10.3 0.1 2.6 1 1 1 2 2 2 2 KaiC IstB_IS21 PF01695.17 EGR30493.1 - 0.00026 20.8 0.0 0.00064 19.5 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 EGR30493.1 - 0.00057 20.1 0.2 0.0014 18.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 EGR30493.1 - 0.00064 19.4 0.0 0.093 12.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGR30493.1 - 0.0015 18.7 0.4 0.0032 17.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 EGR30493.1 - 0.0051 16.6 0.1 0.013 15.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 EGR30493.1 - 0.0079 16.1 0.0 0.029 14.2 0.0 1.8 1 1 0 1 1 1 1 Bacterial dnaA protein DUF815 PF05673.13 EGR30493.1 - 0.0081 15.4 0.0 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.6 EGR30493.1 - 0.012 16.1 0.1 0.041 14.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EGR30493.1 - 0.017 14.5 0.0 0.046 13.1 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 EGR30493.1 - 0.02 14.8 1.8 1.2 9.0 0.0 2.8 2 1 1 3 3 3 0 ATPase domain predominantly from Archaea RNA_helicase PF00910.22 EGR30493.1 - 0.024 15.0 0.5 0.057 13.8 0.0 2.0 2 1 0 2 2 2 0 RNA helicase PhoH PF02562.16 EGR30493.1 - 0.032 13.7 0.1 0.08 12.4 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 EGR30493.1 - 0.044 14.3 0.0 0.044 14.3 0.0 2.6 4 0 0 4 4 2 0 AAA domain TsaE PF02367.17 EGR30493.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EGR30493.1 - 0.073 13.0 0.4 2.2 8.2 0.0 2.9 1 1 1 2 2 2 0 NACHT domain AAA_7 PF12775.7 EGR30493.1 - 0.12 11.8 0.0 0.12 11.8 0.0 2.4 2 1 0 2 2 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 EGR30493.1 - 0.17 11.6 0.7 0.32 10.7 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 EGR30493.1 - 0.25 11.1 5.7 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain Androgen_recep PF02166.16 EGR30493.1 - 3.9 6.2 13.5 5.6 5.7 13.5 1.1 1 0 0 1 1 1 0 Androgen receptor Syja_N PF02383.18 EGR30494.1 - 7.7e-29 101.0 4.3 7.7e-29 101.0 4.3 2.1 2 1 1 3 3 3 1 SacI homology domain DUF2080 PF09853.9 EGR30494.1 - 0.087 12.6 0.2 0.2 11.4 0.2 1.6 1 0 0 1 1 1 0 Putative transposon-encoded protein (DUF2080) VSP PF03302.13 EGR30495.1 - 5.8e-05 22.1 26.7 5.8e-05 22.1 26.7 3.4 1 1 2 3 3 3 1 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EGR30495.1 - 0.00011 22.3 16.3 0.00011 22.3 16.3 4.3 1 1 3 4 4 4 3 Furin-like repeat, cysteine-rich TPR_8 PF13181.6 EGR30496.1 - 1.6e-05 24.8 10.8 0.18 12.1 0.4 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGR30496.1 - 4.3e-05 23.3 4.2 0.097 12.8 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGR30496.1 - 0.0084 16.0 0.4 31 4.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF1360 PF07098.11 EGR30496.1 - 0.04 13.8 0.0 0.17 11.8 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1360) TPR_1 PF00515.28 EGR30496.1 - 3.1 7.7 17.8 0.26 11.2 0.4 4.2 5 0 0 5 5 5 0 Tetratricopeptide repeat GCV_T PF01571.21 EGR30497.1 - 5.7e-76 255.3 0.0 9.3e-76 254.6 0.0 1.3 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EGR30497.1 - 9.7e-15 54.3 0.0 1.7e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain DUF2722 PF10846.8 EGR30497.1 - 4.7e-05 22.5 8.8 7.8e-05 21.8 8.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF4834 PF16118.5 EGR30497.1 - 0.033 15.1 4.7 0.11 13.5 4.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Anoctamin PF04547.12 EGR30497.1 - 0.056 12.3 7.5 0.085 11.7 7.5 1.3 1 0 0 1 1 1 0 Calcium-activated chloride channel MPM1 PF17234.2 EGR30497.1 - 0.061 13.6 10.9 0.23 11.7 10.9 2.0 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 TFIIA PF03153.13 EGR30497.1 - 0.13 12.3 18.4 0.24 11.4 18.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Band_3_cyto PF07565.13 EGR30497.1 - 0.25 11.1 4.5 0.67 9.7 4.5 1.7 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4407 PF14362.6 EGR30497.1 - 1.3 8.3 9.0 2.5 7.4 9.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EIIBC-GUT_N PF03612.14 EGR30497.1 - 3.5 7.3 6.4 13 5.5 6.4 1.9 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Mak16 PF04874.14 EGR30497.1 - 4.7 7.9 15.7 4.5 7.9 9.6 2.8 2 0 0 2 2 2 0 Mak16 protein C-terminal region GTA_holin_3TM PF11351.8 EGR30497.1 - 4.7 7.8 6.3 11 6.6 6.3 1.5 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release DUF4175 PF13779.6 EGR30497.1 - 8.2 4.2 17.3 12 3.7 17.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Tim44 PF04280.15 EGR30498.1 - 0.018 15.2 1.5 0.21 11.7 0.2 2.4 2 0 0 2 2 2 0 Tim44-like domain LIP PF03583.14 EGR30498.1 - 0.16 11.3 1.1 0.28 10.5 1.1 1.4 1 0 0 1 1 1 0 Secretory lipase Anoctamin PF04547.12 EGR30499.1 - 7.9e-40 137.0 20.5 1.3e-23 83.6 9.5 3.1 1 1 2 3 3 3 3 Calcium-activated chloride channel Hydrolase_4 PF12146.8 EGR30500.1 - 3.5e-10 39.6 0.0 7.1e-10 38.6 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR30500.1 - 1.8e-08 34.3 0.0 4.3e-05 23.3 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold DUF915 PF06028.11 EGR30500.1 - 0.00021 20.7 0.1 0.00021 20.7 0.1 2.4 2 1 1 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 EGR30500.1 - 0.012 15.5 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PAF-AH_p_II PF03403.13 EGR30500.1 - 0.026 13.0 0.0 0.051 12.1 0.0 1.5 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Endonuc-BglII PF09195.11 EGR30500.1 - 0.041 13.7 0.2 0.075 12.9 0.2 1.4 1 0 0 1 1 1 0 Restriction endonuclease BglII zf-C3HC4_2 PF13923.6 EGR30501.1 - 3e-10 39.8 10.2 4.6e-10 39.2 10.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGR30501.1 - 1.9e-09 37.4 4.1 1.9e-09 37.4 4.1 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGR30501.1 - 3.5e-08 33.5 10.4 7.8e-08 32.3 10.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EGR30501.1 - 4.5e-07 29.6 11.2 8.3e-07 28.8 11.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGR30501.1 - 8e-07 28.8 6.2 1.2e-06 28.2 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGR30501.1 - 1.3e-06 28.7 9.6 2.1e-06 28.0 9.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGR30501.1 - 3.7e-06 26.8 9.4 6.8e-06 25.9 9.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 EGR30501.1 - 7.5e-05 22.8 4.2 0.00016 21.8 4.2 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-Nse PF11789.8 EGR30501.1 - 0.01 15.7 4.8 0.023 14.5 4.8 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 EGR30501.1 - 0.041 13.7 3.4 0.093 12.6 3.4 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 EGR30501.1 - 0.29 11.0 10.8 5.7 6.9 11.5 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGR30501.1 - 0.59 10.5 8.7 2.2 8.6 8.7 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 EGR30501.1 - 2.7 7.9 6.4 37 4.2 7.4 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Pkinase PF00069.25 EGR30502.1 - 6.7e-67 225.6 1.4 6.7e-67 225.6 1.4 2.4 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30502.1 - 3.7e-45 154.2 0.1 3.7e-45 154.2 0.1 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EGR30502.1 - 0.27 11.1 0.0 0.39 10.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family SecY PF00344.20 EGR30505.1 - 8.2e-69 232.2 14.7 9.6e-69 232.0 14.7 1.0 1 0 0 1 1 1 1 SecY translocase Cyt_bd_oxida_II PF02322.15 EGR30505.1 - 0.55 9.5 6.0 0.11 11.8 2.4 1.8 2 1 0 2 2 2 0 Cytochrome bd terminal oxidase subunit II Metallophos PF00149.28 EGR30506.1 - 2.9e-40 139.0 0.1 3.6e-40 138.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGR30506.1 - 4.4e-20 71.9 1.9 7.8e-19 67.9 1.0 2.4 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain DNA_pol3_delta2 PF13177.6 EGR30507.1 - 1.4e-13 50.9 0.1 2.5e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 EGR30507.1 - 0.00036 21.0 0.1 0.0012 19.3 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGR30507.1 - 0.00098 19.1 0.1 0.0019 18.2 0.1 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EGR30507.1 - 0.002 18.5 0.0 0.014 15.8 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain DNA_pol3_delta PF06144.13 EGR30507.1 - 0.014 15.1 0.3 0.052 13.3 0.0 2.1 2 1 0 2 2 2 0 DNA polymerase III, delta subunit Duffy_binding PF05424.11 EGR30507.1 - 0.016 15.3 0.1 0.029 14.4 0.1 1.7 1 1 0 1 1 1 0 Duffy binding domain Transglut_C PF00927.22 EGR30507.1 - 0.017 15.3 0.2 0.21 11.7 0.0 2.4 1 1 1 2 2 2 0 Transglutaminase family, C-terminal ig like domain ABC_tran PF00005.27 EGR30507.1 - 0.071 13.6 0.4 0.37 11.3 0.0 2.1 2 1 0 2 2 2 0 ABC transporter DUF815 PF05673.13 EGR30507.1 - 0.076 12.2 0.0 0.16 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RuvB_N PF05496.12 EGR30507.1 - 0.094 12.5 0.0 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Metallophos PF00149.28 EGR30508.1 - 1.9e-29 103.7 0.2 3.2e-29 102.9 0.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Arm PF00514.23 EGR30508.1 - 3e-05 23.9 1.8 0.067 13.3 0.0 3.6 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Ric8 PF10165.9 EGR30508.1 - 0.0043 16.2 1.2 0.0043 16.2 1.2 1.7 2 0 0 2 2 2 1 Guanine nucleotide exchange factor synembryn STPPase_N PF16891.5 EGR30508.1 - 0.032 14.7 0.8 0.19 12.2 0.2 2.7 1 1 1 2 2 2 0 Serine-threonine protein phosphatase N-terminal domain TetR_C_13 PF16925.5 EGR30508.1 - 0.058 13.3 0.3 0.15 12.0 0.3 1.7 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Tryp_alpha_amyl PF00234.22 EGR30508.1 - 1.1 9.7 5.8 12 6.4 5.7 2.6 1 1 0 1 1 1 0 Protease inhibitor/seed storage/LTP family ELFV_dehydrog PF00208.21 EGR30509.1 - 5.8e-39 134.3 0.7 2.3e-38 132.3 0.1 2.1 2 0 0 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 EGR30509.1 - 5.8e-38 129.7 0.0 1.1e-37 128.8 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Bac_GDH PF05088.12 EGR30509.1 - 0.0016 16.1 0.9 0.0065 14.0 0.0 1.9 1 1 1 2 2 2 1 Bacterial NAD-glutamate dehydrogenase Peptidase_M41 PF01434.18 EGR30510.1 - 1.5e-53 181.5 2.3 1.5e-53 181.5 2.3 3.4 3 1 1 4 4 4 1 Peptidase family M41 AAA PF00004.29 EGR30510.1 - 7.9e-43 146.1 1.7 1.3e-41 142.1 0.0 3.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGR30510.1 - 2.2e-08 33.8 0.0 6.4e-08 32.3 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGR30510.1 - 2e-05 24.6 0.0 0.00012 22.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGR30510.1 - 2.2e-05 24.9 0.1 0.00064 20.1 0.1 2.9 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.12 EGR30510.1 - 0.0003 20.6 0.1 0.0053 16.5 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGR30510.1 - 0.0011 19.3 1.4 0.041 14.2 0.1 3.5 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 EGR30510.1 - 0.0021 17.6 0.8 1.2 8.6 0.2 2.6 1 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EGR30510.1 - 0.0045 17.2 4.6 0.0057 16.8 0.0 3.4 4 0 0 4 4 4 1 AAA domain IstB_IS21 PF01695.17 EGR30510.1 - 0.0058 16.4 2.3 0.0072 16.1 0.1 2.4 2 1 0 2 2 2 1 IstB-like ATP binding protein AAA_18 PF13238.6 EGR30510.1 - 0.0067 17.0 0.0 0.0067 17.0 0.0 5.3 4 1 1 6 6 5 1 AAA domain Mg_chelatase PF01078.21 EGR30510.1 - 0.007 15.8 0.0 0.02 14.3 0.0 1.8 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EGR30510.1 - 0.053 13.8 3.3 0.054 13.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGR30510.1 - 0.069 13.2 0.0 0.23 11.5 0.0 1.9 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pkinase PF00069.25 EGR30511.1 - 1.9e-44 152.1 4.0 1.9e-44 152.1 4.0 2.8 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30511.1 - 1.1e-21 77.4 0.2 2.9e-21 75.9 0.2 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR30511.1 - 0.018 14.9 0.0 0.1 12.5 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Band_7 PF01145.25 EGR30512.1 - 9.5e-19 68.1 0.1 1.1e-18 67.9 0.1 1.0 1 0 0 1 1 1 1 SPFH domain / Band 7 family Cpta_toxin PF07254.12 EGR30512.1 - 0.081 12.9 2.3 0.15 12.1 2.3 1.4 1 0 0 1 1 1 0 Membrane-bound toxin component of toxin-antitoxin system DUF4200 PF13863.6 EGR30513.1 - 0.0033 17.8 14.6 0.0033 17.8 14.6 2.1 1 1 1 2 2 2 1 Domain of unknown function (DUF4200) ATG16 PF08614.11 EGR30513.1 - 0.0082 16.4 19.8 0.01 16.1 19.8 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) DUF4407 PF14362.6 EGR30513.1 - 0.018 14.4 12.5 0.022 14.1 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TPR_MLP1_2 PF07926.12 EGR30513.1 - 0.16 12.0 27.2 2.2 8.4 0.9 2.9 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ADIP PF11559.8 EGR30513.1 - 0.17 12.0 24.7 0.081 13.0 6.1 2.2 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Sec3_C_2 PF15278.6 EGR30513.1 - 0.21 12.0 8.5 0.042 14.2 4.1 2.2 1 1 2 3 3 3 0 Sec3 exocyst complex subunit Tweety PF04906.13 EGR30513.1 - 0.66 8.6 3.3 0.8 8.3 3.3 1.4 1 0 0 1 1 1 0 Tweety Tup_N PF08581.10 EGR30513.1 - 0.89 9.9 21.7 0.24 11.8 2.1 2.7 1 1 2 3 3 3 0 Tup N-terminal PHM7_cyt PF14703.6 EGR30513.1 - 1.5 9.0 16.2 0.05 13.8 8.8 2.0 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF812 PF05667.11 EGR30513.1 - 1.6 7.5 24.9 2 7.2 24.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) ASL_C PF08328.11 EGR30513.1 - 6.1 7.0 11.6 0.52 10.4 4.8 2.3 1 1 2 3 3 3 0 Adenylosuccinate lyase C-terminal Golgin_A5 PF09787.9 EGR30513.1 - 6.1 6.2 26.1 0.18 11.3 14.6 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 DUF3450 PF11932.8 EGR30513.1 - 9.1 5.5 22.9 0.087 12.1 4.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 EGR30513.1 - 9.7 6.3 11.4 1.2e+02 2.8 9.9 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Evr1_Alr PF04777.13 EGR30514.1 - 1.7e-23 83.0 0.4 1.7e-23 83.0 0.4 2.0 3 0 0 3 3 3 1 Erv1 / Alr family Peptidase_M41 PF01434.18 EGR30515.1 - 1.1e-51 175.4 0.3 2.4e-51 174.3 0.0 1.7 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 EGR30515.1 - 9.1e-46 155.6 0.0 2e-45 154.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGR30515.1 - 1.3e-11 44.1 0.1 3.2e-11 42.9 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGR30515.1 - 4.3e-06 26.6 0.0 1.5e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGR30515.1 - 2.7e-05 24.2 0.0 0.00014 21.9 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGR30515.1 - 0.00011 22.5 1.7 0.16 12.2 0.1 3.1 3 0 0 3 3 3 2 AAA domain AAA_2 PF07724.14 EGR30515.1 - 0.00022 21.4 0.1 0.0096 16.0 0.0 2.7 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGR30515.1 - 0.00035 21.0 0.4 0.0043 17.4 0.4 2.5 1 1 0 1 1 1 1 AAA ATPase domain TIP49 PF06068.13 EGR30515.1 - 0.00047 19.5 0.5 0.00088 18.6 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EGR30515.1 - 0.0066 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_24 PF13479.6 EGR30515.1 - 0.022 14.5 0.2 0.093 12.4 0.1 2.1 2 1 0 2 2 2 0 AAA domain Bac_DnaA PF00308.18 EGR30515.1 - 0.025 14.4 0.0 0.045 13.6 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein AAA_14 PF13173.6 EGR30515.1 - 0.028 14.5 0.0 0.11 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGR30515.1 - 0.042 13.4 1.0 0.54 9.8 0.3 2.3 1 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EGR30515.1 - 0.056 13.9 0.1 0.15 12.5 0.0 1.9 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 EGR30515.1 - 0.062 12.7 1.0 0.12 11.7 0.2 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGR30515.1 - 0.089 12.9 0.0 0.17 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGR30515.1 - 0.12 12.4 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Pkinase PF00069.25 EGR30516.1 - 4e-78 262.4 0.2 9.3e-78 261.2 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30516.1 - 2.1e-42 145.2 0.0 4.5e-42 144.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 EGR30516.1 - 2.7e-26 89.1 7.8 4.6e-07 28.9 0.2 4.8 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 EGR30516.1 - 5.2e-23 79.5 8.9 6.5e-08 31.7 0.1 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGR30516.1 - 1.3e-22 80.0 0.8 5.3e-10 39.6 0.4 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR30516.1 - 6.4e-20 69.3 2.6 0.00013 21.6 0.0 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGR30516.1 - 1.2e-10 41.0 5.6 0.004 17.0 0.4 4.7 1 1 3 4 4 4 3 EF-hand domain pair Kinase-like PF14531.6 EGR30516.1 - 2.2e-09 37.1 0.0 1.3e-08 34.6 0.0 2.2 1 1 1 2 2 2 1 Kinase-like SPARC_Ca_bdg PF10591.9 EGR30516.1 - 2e-07 31.3 6.0 0.00014 22.1 0.1 3.0 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Pkinase_fungal PF17667.1 EGR30516.1 - 0.00013 20.9 0.0 0.00026 19.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR30516.1 - 0.00065 19.1 0.1 0.0012 18.2 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR30516.1 - 0.008 16.1 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Dockerin_1 PF00404.18 EGR30516.1 - 0.017 15.3 1.0 9.1 6.6 0.0 3.8 3 1 0 3 3 3 0 Dockerin type I domain YrbL-PhoP_reg PF10707.9 EGR30516.1 - 0.019 14.5 0.0 0.019 14.5 0.0 2.5 4 0 0 4 4 4 0 PhoP regulatory network protein YrbL RIO1 PF01163.22 EGR30516.1 - 0.027 14.1 0.9 0.054 13.1 0.1 1.9 2 0 0 2 2 2 0 RIO1 family EF-hand_4 PF12763.7 EGR30516.1 - 1 9.4 4.8 1.5 8.8 0.4 3.2 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand NMT_C PF02799.15 EGR30518.1 - 1.2e-78 263.4 5.5 2.5e-78 262.4 4.5 1.9 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain NMT PF01233.19 EGR30518.1 - 8.9e-74 246.7 0.5 2.1e-73 245.4 0.1 1.8 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain Acetyltransf_1 PF00583.25 EGR30518.1 - 0.00034 20.8 0.0 0.00066 19.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Fes1 PF08609.10 EGR30519.1 - 6.5e-05 23.7 6.3 6.5e-05 23.7 6.3 3.2 3 1 1 4 4 4 1 Nucleotide exchange factor Fes1 Arm PF00514.23 EGR30519.1 - 0.021 14.9 0.3 0.091 12.8 0.1 2.2 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EGR30519.1 - 0.094 13.0 0.0 0.36 11.2 0.0 2.0 1 0 0 1 1 1 0 HEAT repeat Ion_trans_2 PF07885.16 EGR30521.1 - 0.011 15.6 1.6 0.017 15.1 1.6 1.3 1 0 0 1 1 1 0 Ion channel US30 PF17624.2 EGR30522.1 - 0.11 11.5 0.3 0.16 11.0 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function Mob1_phocein PF03637.17 EGR30523.1 - 1.2e-72 243.4 3.0 2.3e-72 242.5 3.0 1.4 1 1 0 1 1 1 1 Mob1/phocein family REJ PF02010.15 EGR30524.1 - 2.6e-11 43.0 0.5 3.5e-11 42.6 0.5 1.2 1 0 0 1 1 1 1 REJ domain DUF1444 PF07285.11 EGR30524.1 - 0.00023 20.9 0.1 0.00031 20.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1444) DSPc PF00782.20 EGR30525.1 - 3e-13 49.7 0.1 3.4e-13 49.6 0.1 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EGR30525.1 - 0.0008 19.6 0.2 0.0022 18.1 0.2 1.8 1 1 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EGR30525.1 - 0.0017 17.9 0.0 0.0018 17.9 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Alpha-amylase_C PF02806.18 EGR30526.1 - 2.2e-20 72.9 0.0 5.8e-20 71.6 0.0 1.8 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 EGR30526.1 - 8.1e-15 55.2 4.1 3.6e-13 49.8 1.4 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 EGR30526.1 - 7.8e-11 42.2 0.7 2.2e-10 40.7 0.2 2.1 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DEAD PF00270.29 EGR30527.1 - 7.1e-48 162.7 0.4 1.7e-46 158.2 0.1 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR30527.1 - 2.1e-34 118.2 0.6 2.9e-32 111.3 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGR30527.1 - 1.2e-07 31.9 0.1 5.2e-07 29.8 0.0 1.9 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGR30527.1 - 0.00041 20.7 0.0 0.0012 19.2 0.0 1.7 2 0 0 2 2 2 1 AAA domain UTP25 PF06862.12 EGR30527.1 - 0.0012 17.7 0.1 0.1 11.4 0.0 2.3 2 0 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 EGR30527.1 - 0.0015 17.9 0.0 0.014 14.7 0.0 2.3 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.6 EGR30527.1 - 0.0023 17.7 0.0 0.0038 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain ERCC3_RAD25_C PF16203.5 EGR30527.1 - 0.0037 16.5 0.0 0.007 15.6 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase PhoH PF02562.16 EGR30527.1 - 0.0077 15.7 0.2 0.038 13.4 0.2 2.0 1 1 0 1 1 1 1 PhoH-like protein UvrD-helicase PF00580.21 EGR30527.1 - 0.0095 15.5 0.6 0.17 11.4 0.6 2.2 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain SWI2_SNF2 PF18766.1 EGR30527.1 - 0.01 15.5 0.8 0.16 11.6 0.0 2.3 2 0 0 2 2 2 0 SWI2/SNF2 ATPase Helicase_RecD PF05127.14 EGR30527.1 - 0.031 14.1 0.0 0.067 13.0 0.0 1.6 1 1 0 1 1 1 0 Helicase TniB PF05621.11 EGR30527.1 - 0.038 13.4 0.0 0.21 11.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial TniB protein DUF2075 PF09848.9 EGR30527.1 - 0.053 12.8 0.0 0.09 12.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EGR30527.1 - 0.19 12.0 0.5 0.79 10.0 0.5 2.1 1 1 0 1 1 1 0 AAA domain KIAA1430 PF13879.6 EGR30528.1 - 0.00014 22.5 11.0 0.00014 22.5 11.0 2.5 2 1 0 2 2 2 1 KIAA1430 homologue AAA_14 PF13173.6 EGR30528.1 - 2.3 8.3 7.0 0.18 11.8 1.0 2.1 1 1 2 3 3 3 0 AAA domain PDEase_I PF00233.19 EGR30529.1 - 7e-27 94.7 2.8 1.1e-26 94.1 2.8 1.3 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Robl_LC7 PF03259.17 EGR30530.1 - 4.1e-10 39.3 0.2 1.5e-09 37.5 0.0 1.8 2 0 0 2 2 2 1 Roadblock/LC7 domain MORN PF02493.20 EGR30531.1 - 4.3e-59 193.0 70.6 4.5e-08 32.5 2.0 10.3 10 0 0 10 10 10 10 MORN repeat Solute_trans_a PF03619.16 EGR30532.1 - 3e-74 249.9 27.5 3.7e-74 249.6 27.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF2953 PF11167.8 EGR30532.1 - 0.72 10.0 3.8 1 9.5 0.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) DUF4293 PF14126.6 EGR30532.1 - 1 9.6 9.0 0.13 12.5 1.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4293) ATP-grasp_2 PF08442.10 EGR30533.1 - 2.3e-63 213.4 0.2 3.2e-63 213.0 0.2 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 EGR30533.1 - 1.1e-16 61.0 0.2 1.8e-16 60.3 0.2 1.4 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EGR30533.1 - 0.0001 21.8 0.2 0.00043 19.8 0.2 1.9 1 1 0 1 1 1 1 ATP-grasp domain Endonuc-MspI PF09208.10 EGR30533.1 - 0.021 14.2 1.2 0.18 11.2 0.1 2.2 2 0 0 2 2 2 0 Restriction endonuclease MspI Phage_Orf51 PF06194.11 EGR30533.1 - 0.13 12.3 0.1 0.34 11.0 0.1 1.6 1 0 0 1 1 1 0 Phage Conserved Open Reading Frame 51 MFS_1 PF07690.16 EGR30534.1 - 4e-28 98.4 28.0 3.6e-27 95.2 24.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 EGR30534.1 - 6.6e-13 47.8 11.9 6.6e-13 47.8 11.9 3.7 2 1 1 3 3 3 1 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 EGR30534.1 - 3e-10 39.6 13.0 3e-10 39.6 13.0 2.6 2 1 1 3 3 3 1 Sugar (and other) transporter MFS_1_like PF12832.7 EGR30534.1 - 2.4e-08 33.3 0.7 7.6e-06 25.0 0.0 3.1 2 1 0 2 2 2 1 MFS_1 like family MFS_4 PF06779.14 EGR30534.1 - 1.3e-05 24.7 5.6 1.3e-05 24.7 5.6 1.8 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB Connexin PF00029.19 EGR30534.1 - 0.065 13.0 4.6 0.17 11.6 4.6 1.8 1 0 0 1 1 1 0 Connexin eRF1_2 PF03464.15 EGR30534.1 - 0.076 13.3 0.1 0.13 12.6 0.1 1.3 1 0 0 1 1 1 0 eRF1 domain 2 RP-C_C PF11800.8 EGR30534.1 - 0.098 12.7 6.9 1 9.4 5.3 2.3 2 0 0 2 2 2 0 Replication protein C C-terminal region Pes-10 PF07149.11 EGR30534.1 - 0.18 10.8 14.6 0.26 10.3 14.6 1.2 1 0 0 1 1 1 0 Pes-10 PBP1_TM PF14812.6 EGR30534.1 - 0.34 11.3 5.5 0.66 10.4 5.5 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DNA_pol_phi PF04931.13 EGR30534.1 - 0.55 8.3 11.8 0.86 7.6 11.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi Tim54 PF11711.8 EGR30534.1 - 1.1 8.0 8.9 1.5 7.5 8.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 OSTbeta PF15048.6 EGR30534.1 - 1.4 9.0 0.0 1.4 9.0 0.0 2.4 2 0 0 2 2 1 0 Organic solute transporter subunit beta protein Zip PF02535.22 EGR30534.1 - 3.6 6.7 16.1 0.17 11.1 6.0 3.0 2 1 1 3 3 3 0 ZIP Zinc transporter Trypan_PARP PF05887.11 EGR30534.1 - 4.5 7.3 9.8 7.6 6.5 9.8 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pox_Ag35 PF03286.14 EGR30534.1 - 5 6.9 14.3 8.5 6.1 14.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein FAM60A PF15396.6 EGR30534.1 - 7.2 6.6 9.4 2.6 8.0 6.7 1.7 2 0 0 2 2 1 0 Protein Family FAM60A Peptidase_M16 PF00675.20 EGR30535.1 - 1.4e-35 122.4 0.0 2.3e-35 121.8 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF3169 PF11368.8 EGR30535.1 - 0.0056 16.2 0.3 0.0088 15.6 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) ETRAMP PF09716.10 EGR30535.1 - 0.34 11.0 2.7 0.74 9.9 2.7 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Peptidase_M16_C PF05193.21 EGR30535.1 - 0.39 10.7 3.4 0.5 10.4 0.2 2.5 3 0 0 3 3 3 0 Peptidase M16 inactive domain ADH_zinc_N PF00107.26 EGR30536.1 - 5.6e-24 84.6 0.0 9.4e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGR30536.1 - 2e-11 45.1 0.0 5e-11 43.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGR30536.1 - 5.2e-05 23.1 0.0 0.0041 17.0 0.0 2.4 1 1 1 2 2 2 2 Alcohol dehydrogenase GroES-like domain Rsbr_N PF08678.10 EGR30536.1 - 0.011 15.8 1.8 0.12 12.4 1.6 2.2 1 1 0 1 1 1 0 Rsbr N terminal Glyco_tran_WecB PF03808.13 EGR30536.1 - 0.091 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family MFS_1 PF07690.16 EGR30537.1 - 1.5e-45 155.6 39.3 2.9e-37 128.4 17.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGR30537.1 - 5.9e-13 48.5 31.9 2.3e-11 43.3 31.9 2.2 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 EGR30537.1 - 4.9e-11 41.8 25.9 5.1e-10 38.5 22.6 2.7 1 1 2 3 3 3 2 MFS/sugar transport protein OATP PF03137.20 EGR30537.1 - 1e-05 24.0 23.4 0.00014 20.3 8.7 3.8 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EGR30537.1 - 1.2e-05 24.4 11.7 1.2e-05 24.4 11.7 2.5 2 1 0 2 2 2 1 MFS_1 like family MFS_3 PF05977.13 EGR30537.1 - 0.0019 16.7 4.9 0.01 14.3 0.1 2.7 2 1 0 2 2 2 1 Transmembrane secretion effector Fst_toxin PF13955.6 EGR30537.1 - 4 7.5 6.1 7.2 6.7 2.5 2.7 2 0 0 2 2 2 0 Toxin Fst, type I toxin-antitoxin system LacY_symp PF01306.19 EGR30537.1 - 5.7 5.6 37.7 1.7 7.4 12.7 2.7 2 2 0 2 2 2 0 LacY proton/sugar symporter Ras PF00071.22 EGR30538.1 - 3.5e-44 150.3 5.8 4.6e-42 143.4 5.0 2.2 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EGR30538.1 - 8.9e-22 77.6 2.6 3.9e-18 65.8 2.1 2.7 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR30538.1 - 1.3e-14 54.0 3.7 1.2e-13 50.9 1.9 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGR30538.1 - 1.2e-06 28.2 1.1 2e-06 27.5 1.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGR30538.1 - 0.0017 18.3 0.8 0.25 11.2 0.6 2.6 2 1 1 3 3 3 1 RsgA GTPase cobW PF02492.19 EGR30538.1 - 0.0034 17.0 0.9 0.57 9.7 0.0 3.0 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain DUF3298 PF11738.8 EGR30538.1 - 0.65 11.1 4.0 1.6 9.8 1.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3298) Patatin PF01734.22 EGR30539.1 - 0.029 14.5 0.0 0.03 14.5 0.0 1.2 1 0 0 1 1 1 0 Patatin-like phospholipase Ribosomal_L28 PF00830.19 EGR30540.1 - 3.1e-11 43.3 2.5 3.1e-11 43.3 2.5 2.3 1 1 1 2 2 2 1 Ribosomal L28 family Pkinase PF00069.25 EGR30541.1 - 4.4e-67 226.2 0.1 7.2e-67 225.5 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30541.1 - 6.7e-33 114.1 0.0 1.1e-32 113.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR30541.1 - 7.6e-07 28.2 1.1 1.8e-06 27.0 0.1 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGR30541.1 - 0.01 15.2 2.0 4.1 6.6 0.0 2.9 2 1 0 3 3 3 0 Kinase-like Kdo PF06293.14 EGR30541.1 - 0.013 14.9 0.8 0.028 13.8 0.2 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR30541.1 - 0.013 15.4 0.2 0.049 13.6 0.2 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family DFRP_C PF16543.5 EGR30542.1 - 1.7e-07 31.6 10.3 3.6e-07 30.6 10.1 1.7 1 1 1 2 2 2 1 DRG Family Regulatory Proteins, Tma46 14-3-3 PF00244.20 EGR30543.1 - 2.8e-98 327.8 8.1 3.2e-98 327.7 8.1 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 EGR30543.1 - 0.0044 17.3 0.5 0.16 12.3 0.2 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat FlaF PF07309.11 EGR30543.1 - 0.038 14.0 0.1 0.097 12.7 0.1 1.7 1 0 0 1 1 1 0 Flagellar protein FlaF Peptidase_C1 PF00112.23 EGR30544.1 - 6e-68 229.2 7.4 7.7e-68 228.8 7.4 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGR30544.1 - 2.4e-09 36.5 3.4 9.8e-06 24.6 0.2 2.6 2 1 1 3 3 3 2 Peptidase C1-like family Inhibitor_I29 PF08246.12 EGR30544.1 - 1.8e-06 28.3 0.5 5.6e-05 23.5 0.1 2.8 2 1 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) FeoC PF09012.10 EGR30544.1 - 0.04 14.0 0.2 0.18 11.9 0.1 2.1 2 0 0 2 2 2 0 FeoC like transcriptional regulator AAA_12 PF13087.6 EGR30545.1 - 3.8e-59 199.7 1.5 3.8e-59 199.7 1.5 2.1 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 EGR30545.1 - 1.4e-58 198.8 6.1 2.6e-31 109.4 0.1 3.6 3 1 1 4 4 4 2 AAA domain AAA_19 PF13245.6 EGR30545.1 - 3.5e-09 37.2 2.7 0.0011 19.3 0.3 4.1 4 1 0 4 4 4 2 AAA domain AAA_30 PF13604.6 EGR30545.1 - 4.5e-09 36.3 0.1 0.00038 20.2 0.1 3.1 3 0 0 3 3 3 2 AAA domain Viral_helicase1 PF01443.18 EGR30545.1 - 2e-05 24.5 0.3 0.0057 16.4 0.0 3.3 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 EGR30545.1 - 0.022 14.0 4.6 2 7.6 0.1 3.4 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) PhoH PF02562.16 EGR30545.1 - 0.034 13.6 0.0 0.22 11.0 0.0 2.3 3 0 0 3 3 3 0 PhoH-like protein AAA_16 PF13191.6 EGR30545.1 - 0.039 14.3 0.0 0.13 12.7 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 EGR30545.1 - 0.066 12.3 0.2 0.14 11.2 0.2 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.6 EGR30545.1 - 0.16 12.3 1.8 0.62 10.3 0.3 2.7 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 EGR30545.1 - 0.22 11.5 9.9 0.056 13.4 2.5 3.4 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Guanylate_cyc PF00211.20 EGR30547.1 - 2.4e-34 118.6 1.5 4.7e-34 117.6 1.5 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain PhoLip_ATPase_C PF16212.5 EGR30547.1 - 1.8e-11 44.3 45.3 1.8e-11 44.3 45.3 4.4 3 1 1 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal DUF5624 PF18538.1 EGR30547.1 - 0.12 12.5 2.0 0.39 10.8 2.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5624) Penicil_amidase PF01804.18 EGR30548.1 - 1.3e-163 546.5 0.0 1.6e-163 546.3 0.0 1.0 1 0 0 1 1 1 1 Penicillin amidase MbeD_MobD PF04899.12 EGR30549.1 - 0.19 11.9 4.0 1 9.6 0.1 3.1 2 1 0 2 2 2 0 MbeD/MobD like WD40 PF00400.32 EGR30550.1 - 3.8e-10 40.2 1.3 0.00099 19.9 0.1 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR30550.1 - 0.00017 21.8 4.5 1.4 9.2 0.1 5.7 4 1 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PapC_C PF13953.6 EGR30550.1 - 0.0093 15.8 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 PapC C-terminal domain MORN PF02493.20 EGR30551.1 - 3e-24 83.4 76.9 9.8e-07 28.3 0.6 12.6 13 1 0 13 13 13 9 MORN repeat TPR_12 PF13424.6 EGR30552.1 - 1.7e-18 66.6 8.3 1.8e-06 28.2 0.1 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGR30552.1 - 3.1e-10 39.4 20.0 0.0018 18.4 0.2 6.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGR30552.1 - 6.5e-08 32.1 19.5 0.081 13.1 0.2 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGR30552.1 - 1.1e-07 32.0 6.7 8.3 7.3 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGR30552.1 - 1.3e-07 31.1 6.3 0.56 10.4 0.0 6.2 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGR30552.1 - 2.1e-07 31.4 5.9 0.13 12.8 1.4 4.1 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGR30552.1 - 9.7e-07 28.4 21.2 0.78 9.7 0.1 6.5 6 0 0 6 6 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR30552.1 - 1e-05 25.7 15.0 0.1 12.9 6.0 4.5 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EGR30552.1 - 0.00012 21.8 2.8 15 5.6 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EGR30552.1 - 0.00044 19.7 0.9 0.00065 19.2 0.2 1.6 2 0 0 2 2 2 1 MalT-like TPR region TPR_14 PF13428.6 EGR30552.1 - 0.0037 18.0 0.1 52 5.0 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGR30552.1 - 0.0038 17.9 0.1 12 6.7 0.3 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat DUF2225 PF09986.9 EGR30552.1 - 0.0085 15.8 11.0 0.023 14.4 3.3 3.1 1 1 3 4 4 4 2 Uncharacterized protein conserved in bacteria (DUF2225) MIT PF04212.18 EGR30552.1 - 0.13 12.3 10.5 4.4 7.4 1.0 4.8 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_17 PF13431.6 EGR30552.1 - 0.29 11.6 7.7 42 4.8 0.1 5.8 6 1 0 6 6 5 0 Tetratricopeptide repeat DUF4810 PF16068.5 EGR30552.1 - 0.62 10.6 8.6 2.1 9.0 0.3 3.6 2 1 2 4 4 3 0 Domain of unknown function (DUF4810) BOF PF04076.13 EGR30552.1 - 0.69 10.0 4.4 10 6.3 0.0 3.5 4 0 0 4 4 4 0 Bacterial OB fold (BOF) protein RPN7 PF10602.9 EGR30552.1 - 3.7 7.2 12.7 0.69 9.6 0.8 3.6 1 1 3 4 4 4 0 26S proteasome subunit RPN7 Methyltransf_8 PF05148.15 EGR30553.1 - 2.6e-56 190.9 7.9 1.7e-55 188.3 1.9 2.0 1 1 1 2 2 2 2 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EGR30553.1 - 1.2e-08 35.5 0.1 4.2e-07 30.5 0.0 3.1 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGR30553.1 - 8.1e-07 29.7 0.0 0.00044 20.9 0.0 2.9 2 2 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGR30553.1 - 3.7e-06 26.9 0.0 4.9e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGR30553.1 - 0.00018 21.3 3.1 0.046 13.5 0.1 2.6 2 1 1 3 3 3 2 Methyltransferase domain MTS PF05175.14 EGR30553.1 - 0.0016 18.1 0.0 0.31 10.6 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase small domain AdoMet_MTase PF07757.13 EGR30553.1 - 0.029 14.7 0.7 0.11 12.9 0.1 2.1 2 1 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 EGR30553.1 - 0.042 13.8 0.0 0.071 13.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 EGR30553.1 - 0.06 12.9 0.3 0.6 9.7 0.0 2.4 2 1 1 3 3 3 0 Methionine biosynthesis protein MetW VGPC1_C PF16799.5 EGR30553.1 - 0.064 13.3 1.7 3.3 7.8 0.5 2.4 2 0 0 2 2 2 0 C-terminal membrane-localisation domain of ion-channel, VCN1 Na_H_Exchanger PF00999.21 EGR30554.1 - 3.9e-47 160.9 36.4 4.9e-47 160.5 36.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family SAPS PF04499.15 EGR30555.1 - 1.3e-21 77.0 29.2 1.8e-16 60.0 6.6 3.1 1 1 2 3 3 3 2 SIT4 phosphatase-associated protein SPRY PF00622.28 EGR30555.1 - 2.9e-07 30.6 0.0 1.1e-05 25.5 0.0 2.7 2 0 0 2 2 2 1 SPRY domain Hydrolase_4 PF12146.8 EGR30556.1 - 6.3e-11 42.0 0.0 1.4e-05 24.5 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR30556.1 - 2.4e-08 33.9 0.1 0.003 17.2 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold FSH1 PF03959.13 EGR30556.1 - 0.00015 21.5 0.0 0.00021 21.1 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 EGR30556.1 - 0.0026 17.3 0.0 0.0057 16.2 0.0 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 EGR30556.1 - 0.0041 17.1 0.1 1.7 8.5 0.0 2.3 1 1 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 EGR30556.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family Ser_hydrolase PF06821.13 EGR30556.1 - 0.014 15.2 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase DUF4948 PF16306.5 EGR30556.1 - 0.026 14.3 0.1 0.051 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4948) LIDHydrolase PF10230.9 EGR30556.1 - 0.029 13.9 0.1 8.8 5.8 0.0 2.1 1 1 0 2 2 2 0 Lipid-droplet associated hydrolase LIP PF03583.14 EGR30556.1 - 0.05 12.9 0.1 0.11 11.8 0.1 1.5 1 1 0 1 1 1 0 Secretory lipase Abhydrolase_2 PF02230.16 EGR30556.1 - 0.13 12.0 0.7 0.91 9.3 0.7 2.1 1 1 0 1 1 1 0 Phospholipase/Carboxylesterase 3HBOH PF10605.9 EGR30556.1 - 0.19 9.9 0.0 0.23 9.6 0.0 1.1 1 0 0 1 1 1 0 3HB-oligomer hydrolase (3HBOH) MFS_1 PF07690.16 EGR30557.1 - 1.5e-10 40.6 4.6 1.5e-10 40.6 4.6 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGR30557.1 - 1.9e-10 40.2 12.6 2.3e-10 39.9 12.6 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.6 EGR30557.1 - 0.001 17.7 4.4 0.001 17.7 4.4 2.3 3 0 0 3 3 3 1 MFS/sugar transport protein Cytokin_check_N PF10407.9 EGR30557.1 - 0.0069 16.3 0.9 0.016 15.1 0.9 1.6 1 0 0 1 1 1 1 Cdc14 phosphatase binding protein N-terminus ANAPC8 PF04049.13 EGR30558.1 - 5.7e-27 94.5 5.2 1.4e-26 93.2 5.2 1.7 1 0 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 EGR30558.1 - 2.6e-26 90.3 15.5 9.3e-07 28.4 0.0 8.3 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGR30558.1 - 2.1e-24 83.6 22.0 0.00018 21.4 0.1 9.5 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 EGR30558.1 - 1.1e-23 81.4 23.8 2.2e-05 24.3 0.1 8.9 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_14 PF13428.6 EGR30558.1 - 1.7e-16 59.5 0.1 3.5e-05 24.3 0.1 6.7 4 2 2 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGR30558.1 - 2e-13 49.8 7.1 1.9e-10 40.2 0.3 5.3 4 2 1 5 5 5 1 TPR repeat TPR_12 PF13424.6 EGR30558.1 - 2.6e-12 46.8 17.9 3.3e-05 24.1 0.2 7.1 6 2 1 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGR30558.1 - 4.6e-10 39.9 5.7 0.0043 17.5 0.0 6.3 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGR30558.1 - 1.5e-07 30.9 4.4 1.5 9.0 0.1 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGR30558.1 - 1.9e-07 31.6 5.4 1.3e-05 25.8 0.0 5.4 5 1 2 7 7 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGR30558.1 - 1.6e-06 28.0 9.3 0.0018 18.5 0.1 5.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGR30558.1 - 4.2e-06 27.0 16.7 7.1 7.5 0.1 8.4 9 0 0 9 9 9 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR30558.1 - 5e-06 26.6 27.7 0.11 12.7 2.1 6.7 5 2 3 8 8 8 3 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 EGR30558.1 - 3.9e-05 22.8 4.4 0.0068 15.4 0.0 4.5 4 2 2 6 6 6 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 EGR30558.1 - 0.00017 20.9 3.1 0.81 8.8 0.1 4.6 2 1 1 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGR30558.1 - 0.0068 16.5 0.1 7.8 6.7 0.0 3.5 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGR30558.1 - 0.012 15.4 9.6 0.79 9.7 0.0 6.4 7 0 0 7 7 7 0 Tetratricopeptide repeat T2SSF PF00482.23 EGR30558.1 - 0.19 11.7 0.0 0.59 10.1 0.0 1.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F RPN7 PF10602.9 EGR30558.1 - 8.6 6.0 13.6 4.2 7.1 0.9 4.3 4 2 1 5 5 5 0 26S proteasome subunit RPN7 Kazal_1 PF00050.21 EGR30559.1 - 0.00076 19.4 11.3 0.0012 18.8 4.6 7.1 6 2 0 6 6 6 3 Kazal-type serine protease inhibitor domain Syja_N PF02383.18 EGR30560.1 - 8.1e-50 169.9 4.4 8.1e-50 169.9 4.4 1.8 1 1 0 1 1 1 1 SacI homology domain Exo_endo_phos PF03372.23 EGR30560.1 - 1.9e-06 27.6 0.0 3.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF5354 PF17305.2 EGR30560.1 - 0.011 15.9 1.0 0.023 14.9 0.1 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5354) Syja_N PF02383.18 EGR30561.1 - 1.7e-58 198.4 5.9 1.7e-58 198.4 5.9 3.7 4 0 0 4 4 4 1 SacI homology domain Exo_endo_phos PF03372.23 EGR30561.1 - 0.0043 16.6 0.1 0.0097 15.4 0.1 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Rol_Rep_N PF18106.1 EGR30561.1 - 0.08 13.3 0.0 0.08 13.3 0.0 3.7 3 1 1 4 4 4 0 Rolling Circle replication initiation protein N-terminal domain Ion_trans_2 PF07885.16 EGR30563.1 - 9.9e-14 51.1 1.4 9.9e-14 51.1 1.4 2.3 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 EGR30563.1 - 1.1e-13 51.0 24.2 1.1e-13 51.0 24.2 2.2 2 0 0 2 2 2 1 Ion transport protein cNMP_binding PF00027.29 EGR30563.1 - 9.8e-10 38.4 0.1 3.1e-09 36.8 0.1 1.8 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain zf-CCHC_4 PF14392.6 EGR30563.1 - 0.046 13.5 0.1 0.1 12.3 0.1 1.6 1 0 0 1 1 1 0 Zinc knuckle Lig_chan PF00060.26 EGR30563.1 - 0.054 13.3 0.3 0.14 12.0 0.3 1.7 1 0 0 1 1 1 0 Ligand-gated ion channel EF-hand_7 PF13499.6 EGR30564.1 - 0.00012 22.5 8.1 0.0033 17.8 0.4 2.3 2 0 0 2 2 2 2 EF-hand domain pair Blt1 PF12754.7 EGR30564.1 - 0.0064 16.8 0.0 0.012 15.9 0.0 1.4 1 0 0 1 1 1 1 Blt1 N-terminal domain EFhand_Ca_insen PF08726.10 EGR30564.1 - 0.0093 16.0 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_6 PF13405.6 EGR30564.1 - 0.072 13.1 9.7 0.1 12.6 0.2 3.9 4 1 0 4 4 4 0 EF-hand domain LRR_8 PF13855.6 EGR30565.1 - 3.6e-10 39.5 10.5 1.1e-06 28.3 2.8 2.8 1 1 1 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 EGR30565.1 - 3.3e-07 30.5 15.6 9.5e-07 29.1 3.9 3.9 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGR30565.1 - 0.15 12.1 2.5 6.2 7.1 0.1 3.7 3 0 0 3 3 3 0 Leucine Rich repeat WD40 PF00400.32 EGR30566.1 - 1.7e-17 63.4 0.8 0.0015 19.3 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EGR30566.1 - 1.5e-07 30.5 9.3 3.9e-06 25.9 1.1 3.5 3 1 1 4 4 4 2 Nup133 N terminal like ANAPC4_WD40 PF12894.7 EGR30566.1 - 2.6e-06 27.7 1.3 0.033 14.5 0.0 4.8 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGR30566.1 - 0.0068 15.1 2.2 3 6.4 0.1 3.8 2 2 2 4 4 4 2 Nucleoporin Nup120/160 ELYS-bb PF16687.5 EGR30566.1 - 0.012 14.2 0.0 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 beta-propeller of ELYS nucleoporin GerPE PF10970.8 EGR30566.1 - 0.075 13.2 0.3 0.16 12.1 0.3 1.5 1 0 0 1 1 1 0 Spore germination protein GerPE Pkinase PF00069.25 EGR30567.1 - 9.8e-33 113.6 0.7 4.9e-28 98.2 0.1 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30567.1 - 4.7e-16 58.8 0.0 3.3e-13 49.5 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR30567.1 - 5.2e-06 25.5 0.1 6.2e-06 25.2 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 EGR30567.1 - 0.00019 20.5 0.3 0.00022 20.3 0.3 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.14 EGR30567.1 - 0.0033 16.8 0.2 0.0046 16.3 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR30567.1 - 0.085 12.8 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Hfq PF17209.3 EGR30567.1 - 0.093 12.4 1.1 0.38 10.4 0.3 2.2 2 0 0 2 2 2 0 Hfq protein DnaJ_C PF01556.18 EGR30568.1 - 1.4e-30 106.3 0.0 9.1e-30 103.7 0.0 2.0 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGR30568.1 - 3.4e-23 81.6 4.5 7.1e-23 80.5 4.5 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGR30568.1 - 1.3e-13 51.0 13.9 2.4e-13 50.3 13.9 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGR30568.1 - 0.00016 21.6 9.7 0.051 13.6 1.4 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EGR30568.1 - 0.0011 18.9 3.6 0.25 11.4 0.8 2.4 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 EGR30568.1 - 0.062 13.3 10.1 0.12 12.4 10.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon TackOD1 PF18551.1 EGR30568.1 - 0.067 12.8 9.8 0.32 10.7 0.9 3.1 2 1 1 3 3 3 0 Thaumarchaeal output domain 1 Lar_restr_allev PF14354.6 EGR30568.1 - 1 9.8 14.0 0.14 12.6 3.9 3.1 2 1 1 3 3 3 0 Restriction alleviation protein Lar zf-RING_10 PF16685.5 EGR30568.1 - 7.4 6.8 7.3 1.8 8.8 1.3 2.3 1 1 1 2 2 2 0 zinc RING finger of MSL2 DAO_C PF16901.5 EGR30569.1 - 1.9e-12 47.2 0.0 5e-12 45.8 0.0 1.8 1 1 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase DAO PF01266.24 EGR30569.1 - 6.1e-07 29.3 0.0 7.8e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Guanylate_cyc PF00211.20 EGR30570.1 - 1.3e-88 295.5 8.2 7.5e-47 159.3 1.9 2.8 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Hydrolase_3 PF08282.12 EGR30570.1 - 1.7e-06 28.0 6.4 1.7e-06 28.0 6.4 9.0 6 2 2 8 8 8 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGR30570.1 - 4.9e-06 26.2 0.0 4.9e-06 26.2 0.0 4.3 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EGR30570.1 - 1.3e-05 25.6 0.0 0.092 13.0 0.0 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 EGR30571.1 - 1.1e-45 156.0 1.7 1.4e-45 155.8 1.7 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30571.1 - 2.8e-36 125.1 0.4 3.5e-36 124.8 0.4 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR30571.1 - 0.0017 17.2 0.0 0.0028 16.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase NPCC PF08058.11 EGR30571.1 - 0.014 15.4 1.6 0.019 15.0 1.6 1.2 1 0 0 1 1 1 0 Nuclear pore complex component Haspin_kinase PF12330.8 EGR30571.1 - 0.02 13.8 1.4 0.027 13.4 1.4 1.4 1 1 0 1 1 1 0 Haspin like kinase domain UCH PF00443.29 EGR30572.1 - 8.2e-28 97.6 8.0 9.5e-28 97.4 8.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR30572.1 - 3.8e-14 53.0 14.6 8.6e-14 51.8 14.6 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EGR30572.1 - 0.00019 21.0 8.4 0.0007 19.1 8.4 1.7 1 1 0 1 1 1 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase DZR PF12773.7 EGR30572.1 - 0.017 15.1 1.4 2.6 8.1 0.4 2.5 2 0 0 2 2 2 0 Double zinc ribbon Plus-3 PF03126.18 EGR30572.1 - 0.067 13.7 0.9 0.17 12.4 0.2 1.9 2 0 0 2 2 2 0 Plus-3 domain zf-FPG_IleRS PF06827.14 EGR30572.1 - 0.078 12.9 2.8 0.21 11.5 0.2 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS AAA_12 PF13087.6 EGR30573.1 - 4e-35 121.3 5.1 4e-35 121.3 5.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EGR30573.1 - 5.2e-06 26.4 0.1 1.7e-05 24.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain PseudoU_synth_2 PF00849.22 EGR30574.1 - 2.1e-29 102.7 0.3 4.1e-29 101.7 0.3 1.5 1 0 0 1 1 1 1 RNA pseudouridylate synthase Tudor-knot PF11717.8 EGR30575.1 - 0.08 12.8 0.3 0.19 11.6 0.3 1.6 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF777 PF05606.11 EGR30576.1 - 0.016 14.9 0.5 0.016 14.9 0.5 2.1 1 1 0 2 2 2 0 Borrelia burgdorferi protein of unknown function (DUF777) NOA36 PF06524.12 EGR30576.1 - 2.7 7.2 6.9 5.1 6.3 6.9 1.4 1 0 0 1 1 1 0 NOA36 protein UQ_con PF00179.26 EGR30577.1 - 9.7e-47 158.1 0.1 1.2e-46 157.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UBA PF00627.31 EGR30577.1 - 5.4e-08 32.6 0.0 9.6e-08 31.8 0.0 1.4 1 0 0 1 1 1 1 UBA/TS-N domain Prok-E2_B PF14461.6 EGR30577.1 - 0.00037 20.2 0.1 0.0034 17.1 0.0 2.0 1 1 1 2 2 2 1 Prokaryotic E2 family B RWD PF05773.22 EGR30577.1 - 0.0018 18.5 0.1 0.0035 17.6 0.0 1.6 2 0 0 2 2 2 1 RWD domain PHA_synth_III_E PF09712.10 EGR30577.1 - 0.015 14.4 0.2 0.018 14.1 0.2 1.1 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) DUF3837 PF12939.7 EGR30577.1 - 0.024 15.1 0.2 0.042 14.3 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3837) UEV PF05743.13 EGR30577.1 - 0.1 12.5 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 UEV domain zf-C3HC4_3 PF13920.6 EGR30578.1 - 5.7e-14 51.7 7.1 8.6e-14 51.1 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGR30578.1 - 3.2e-06 26.9 7.4 3.2e-06 26.9 7.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGR30578.1 - 2.8e-05 23.9 6.4 4.4e-05 23.3 6.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGR30578.1 - 0.00037 20.8 7.8 0.00037 20.8 7.8 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGR30578.1 - 0.00091 19.0 8.2 0.00091 19.0 7.0 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Kazal_1 PF00050.21 EGR30578.1 - 0.11 12.5 0.5 0.11 12.5 0.5 2.2 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain DZR PF12773.7 EGR30578.1 - 0.25 11.4 4.5 0.18 11.9 0.7 2.1 2 0 0 2 2 2 0 Double zinc ribbon zf-RING_5 PF14634.6 EGR30578.1 - 0.34 10.9 7.9 0.28 11.2 6.4 1.7 2 1 0 2 2 2 0 zinc-RING finger domain Porphobil_deam PF01379.20 EGR30579.1 - 1.5e-61 207.5 0.0 2.1e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain RabGAP-TBC PF00566.18 EGR30579.1 - 1.4e-19 70.7 3.5 2.8e-19 69.6 3.5 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Porphobil_deamC PF03900.15 EGR30579.1 - 4.3e-13 49.4 0.0 9.3e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain PTRF_SDPR PF15237.6 EGR30579.1 - 0.016 14.8 1.2 0.064 12.9 0.1 2.0 2 0 0 2 2 2 0 PTRF/SDPR family dUTPase PF00692.19 EGR30580.1 - 1.3e-37 128.4 0.0 1.7e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 dUTPase Na_H_Exchanger PF00999.21 EGR30581.1 - 3.1e-36 125.0 26.2 4.7e-36 124.4 18.2 2.2 2 0 0 2 2 2 2 Sodium/hydrogen exchanger family cNMP_binding PF00027.29 EGR30581.1 - 0.0054 16.8 0.0 0.013 15.5 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Mem_trans PF03547.18 EGR30581.1 - 0.049 12.0 3.7 0.099 11.0 3.7 1.5 1 0 0 1 1 1 0 Membrane transport protein MetOD2 PF18548.1 EGR30581.1 - 0.11 12.6 2.3 5.5 7.2 0.3 3.4 3 0 0 3 3 3 0 Metanogen output domain 2 DUF2189 PF09955.9 EGR30581.1 - 0.24 11.6 3.4 1.1 9.5 1.0 2.6 1 1 1 2 2 2 0 Predicted integral membrane protein (DUF2189) Pkinase PF00069.25 EGR30582.1 - 7.5e-75 251.7 0.2 7.5e-75 251.7 0.2 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30582.1 - 2.9e-37 128.4 0.7 5e-33 114.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 EGR30582.1 - 6.6e-05 22.4 0.2 0.00014 21.2 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGR30582.1 - 0.00016 21.3 0.3 0.00016 21.3 0.3 2.7 2 1 1 3 3 3 1 Choline/ethanolamine kinase APH PF01636.23 EGR30582.1 - 0.0027 17.6 0.0 0.0042 17.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family MORN PF02493.20 EGR30583.1 - 3.2e-51 168.3 65.9 7.1e-07 28.8 0.3 10.5 10 0 0 10 10 10 10 MORN repeat UPF0242 PF06785.11 EGR30583.1 - 9.8 6.2 22.4 16 5.5 22.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Sas10 PF09368.10 EGR30584.1 - 6.2e-14 52.2 2.4 6.2e-14 52.2 2.4 3.0 2 1 1 3 3 3 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 EGR30584.1 - 8.2 7.1 10.3 1.1e+02 3.5 10.3 3.0 1 1 0 1 1 1 0 Sas10/Utp3/C1D family ubiquitin PF00240.23 EGR30585.1 - 2.2e-14 52.9 3.4 2.2e-14 52.9 3.4 3.7 3 0 0 3 3 3 1 Ubiquitin family Pex14_N PF04695.13 EGR30585.1 - 0.0026 18.4 122.4 0.041 14.5 16.1 5.9 7 0 0 7 7 7 5 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2407 PF10302.9 EGR30585.1 - 0.0027 18.3 1.9 0.0027 18.3 1.9 7.1 6 3 0 6 6 6 1 DUF2407 ubiquitin-like domain NUDIX PF00293.28 EGR30586.1 - 7.6e-13 48.6 0.0 1.1e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF1186 PF06685.11 EGR30586.1 - 0.025 14.0 0.4 0.039 13.3 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1186) Pkinase PF00069.25 EGR30587.1 - 4.8e-13 49.1 0.1 1.5e-07 31.1 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain NIF PF03031.18 EGR30588.1 - 0.071 12.9 0.1 0.11 12.2 0.0 1.4 2 0 0 2 2 2 0 NLI interacting factor-like phosphatase AAA PF00004.29 EGR30589.1 - 1.3e-41 142.1 2.1 3.5e-39 134.2 0.1 2.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGR30589.1 - 7.7e-09 35.2 0.0 1.7e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EGR30589.1 - 3e-08 34.0 1.0 0.0053 17.0 0.0 3.5 2 1 1 3 3 3 2 AAA domain AAA_2 PF07724.14 EGR30589.1 - 4.8e-08 33.3 0.1 5.9e-07 29.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EGR30589.1 - 7.7e-07 28.7 0.1 0.00053 19.4 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EGR30589.1 - 5.4e-06 26.2 0.5 0.0058 16.4 0.0 2.7 3 0 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGR30589.1 - 5.5e-06 26.4 0.4 0.00036 20.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGR30589.1 - 7.5e-06 26.4 1.9 0.0073 16.7 0.1 3.1 3 1 0 3 3 2 2 AAA ATPase domain AAA_7 PF12775.7 EGR30589.1 - 1.3e-05 24.8 0.3 0.0073 15.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region TIP49 PF06068.13 EGR30589.1 - 1.5e-05 24.4 0.1 0.027 13.7 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_33 PF13671.6 EGR30589.1 - 1.6e-05 25.1 0.0 0.0028 17.8 0.0 2.6 2 1 0 2 2 2 1 AAA domain ATPase PF06745.13 EGR30589.1 - 4.3e-05 23.0 0.7 0.0067 15.8 0.0 3.1 2 1 0 2 2 2 1 KaiC AAA_18 PF13238.6 EGR30589.1 - 4.3e-05 24.0 0.4 0.022 15.3 0.0 2.9 2 1 0 2 2 2 1 AAA domain TsaE PF02367.17 EGR30589.1 - 6.3e-05 23.0 0.0 0.26 11.3 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ResIII PF04851.15 EGR30589.1 - 0.00025 21.1 1.0 1.2 9.1 0.0 3.1 2 2 1 3 3 2 2 Type III restriction enzyme, res subunit IstB_IS21 PF01695.17 EGR30589.1 - 0.0003 20.6 0.0 0.1 12.3 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activat PF00158.26 EGR30589.1 - 0.00037 20.2 0.1 1.1 8.9 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain RNA_helicase PF00910.22 EGR30589.1 - 0.00055 20.3 0.2 0.019 15.4 0.0 3.2 3 1 1 4 4 2 1 RNA helicase TniB PF05621.11 EGR30589.1 - 0.00074 19.0 0.5 1.5 8.2 0.0 3.3 2 1 0 2 2 2 1 Bacterial TniB protein ABC_tran PF00005.27 EGR30589.1 - 0.0015 19.1 1.0 0.032 14.8 0.1 2.7 2 0 0 2 2 2 1 ABC transporter NB-ARC PF00931.22 EGR30589.1 - 0.0016 17.7 0.4 1.1 8.4 0.0 2.9 3 1 1 4 4 4 1 NB-ARC domain PhoH PF02562.16 EGR30589.1 - 0.0017 17.8 0.5 0.85 9.0 0.0 2.9 3 0 0 3 3 3 1 PhoH-like protein NACHT PF05729.12 EGR30589.1 - 0.0026 17.7 0.5 0.53 10.2 0.0 3.1 2 1 0 2 2 2 1 NACHT domain AAA_19 PF13245.6 EGR30589.1 - 0.0028 18.0 0.2 0.024 14.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGR30589.1 - 0.0036 16.9 0.4 0.3 10.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.11 EGR30589.1 - 0.0052 16.6 0.0 0.25 11.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) CDC48_2 PF02933.17 EGR30589.1 - 0.0053 16.5 1.5 0.013 15.2 0.2 2.3 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_14 PF13173.6 EGR30589.1 - 0.011 15.7 0.0 0.12 12.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGR30589.1 - 0.013 14.7 0.2 3.1 7.0 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin DUF2075 PF09848.9 EGR30589.1 - 0.016 14.4 0.6 0.46 9.7 0.0 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 EGR30589.1 - 0.017 14.9 2.7 0.2 11.3 0.0 3.3 2 2 1 3 3 3 0 AAA domain AAA_17 PF13207.6 EGR30589.1 - 0.026 14.9 0.4 2.1 8.8 0.0 2.8 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.22 EGR30589.1 - 0.029 14.0 0.1 8.3 6.0 0.0 2.7 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Vps4_C PF09336.10 EGR30589.1 - 0.05 13.6 0.1 0.19 11.8 0.1 2.0 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain Rad17 PF03215.15 EGR30589.1 - 0.054 13.4 1.7 0.1 12.5 0.1 2.5 3 1 0 3 3 2 0 Rad17 P-loop domain APS_kinase PF01583.20 EGR30589.1 - 0.061 13.2 0.1 7.8 6.4 0.1 2.5 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_28 PF13521.6 EGR30589.1 - 0.065 13.5 0.1 0.19 12.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain T2SSE PF00437.20 EGR30589.1 - 0.071 12.2 0.1 7.7 5.5 0.1 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein ATP-synt_ab PF00006.25 EGR30589.1 - 0.078 12.6 0.0 0.17 11.5 0.0 1.6 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_11 PF13086.6 EGR30589.1 - 0.12 12.1 0.2 0.27 11.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGR30589.1 - 0.15 11.8 0.0 3.4 7.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGR30589.1 - 0.15 11.8 0.3 15 5.4 0.1 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain ATPase_2 PF01637.18 EGR30589.1 - 0.56 10.1 0.0 0.56 10.1 0.0 3.9 3 2 2 5 5 5 0 ATPase domain predominantly from Archaea Adap_comp_sub PF00928.21 EGR30590.1 - 2.6e-62 210.6 7.3 3.5e-62 210.1 7.3 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Anemone_cytotox PF06369.12 EGR30590.1 - 0.047 13.3 0.1 0.076 12.6 0.1 1.2 1 0 0 1 1 1 0 Sea anemone cytotoxic protein Clat_adaptor_s PF01217.20 EGR30590.1 - 0.047 13.6 1.1 0.17 11.8 0.1 2.1 2 0 0 2 2 2 0 Clathrin adaptor complex small chain ASH PF15780.5 EGR30591.1 - 0.015 15.5 12.1 7.5 6.8 0.0 7.0 8 0 0 8 8 8 0 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin IF4E PF01652.18 EGR30592.1 - 2.6e-23 82.6 0.3 3.6e-23 82.1 0.3 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DnaJ_CXXCXGXG PF00684.19 EGR30593.1 - 0.099 13.0 13.6 0.31 11.4 13.6 1.7 1 1 0 1 1 1 0 DnaJ central domain DNA_ligase_A_M PF01068.21 EGR30594.1 - 2.4e-44 151.4 4.3 7e-44 149.9 4.3 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGR30594.1 - 1e-30 107.3 0.3 1.7e-29 103.3 0.0 2.4 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EGR30594.1 - 2.3e-15 57.0 0.5 2.1e-14 53.9 0.0 2.8 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EGR30594.1 - 8e-10 39.3 2.1 2.3e-09 37.8 2.1 1.8 1 0 0 1 1 1 1 RNA ligase BRCT_2 PF16589.5 EGR30594.1 - 2.6e-08 34.1 0.8 2.6e-08 34.1 0.8 2.7 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_IV PF11411.8 EGR30594.1 - 6.5e-06 26.2 0.1 2.1e-05 24.5 0.1 1.9 1 0 0 1 1 1 1 DNA ligase IV LIG3_BRCT PF16759.5 EGR30594.1 - 0.00084 19.6 0.1 0.0024 18.1 0.1 1.8 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain BRCT PF00533.26 EGR30594.1 - 0.013 15.8 0.5 0.084 13.3 0.5 2.5 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain BMF PF15185.6 EGR30594.1 - 0.12 12.0 3.3 2.1 8.0 3.7 2.2 2 0 0 2 2 2 0 Bcl-2-modifying factor, apoptosis NIF PF03031.18 EGR30595.1 - 4.5e-53 179.2 3.7 4.5e-53 179.2 3.7 2.5 2 1 0 2 2 2 2 NLI interacting factor-like phosphatase AlbA_2 PF04326.14 EGR30596.1 - 4.7e-09 36.6 0.0 7.7e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Putative DNA-binding domain Phage_Coat_Gp8 PF05371.12 EGR30596.1 - 0.16 11.8 0.2 3 7.7 0.0 2.2 2 0 0 2 2 2 0 Phage major coat protein, Gp8 Beach PF02138.18 EGR30597.1 - 3.1e-106 354.8 3.4 5.3e-106 354.0 3.4 1.4 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 EGR30597.1 - 9.1e-05 23.2 0.0 2 9.4 0.0 4.1 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR30597.1 - 0.073 13.4 0.0 2.5 8.5 0.0 3.0 2 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain GATase_2 PF00310.21 EGR30597.1 - 0.14 10.8 0.8 0.23 10.1 0.8 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Ank_4 PF13637.6 EGR30598.1 - 8.6e-12 45.3 0.2 1.5e-07 31.9 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGR30598.1 - 2.2e-07 31.4 0.0 7.3e-07 29.7 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGR30598.1 - 2.4e-07 30.9 0.0 0.0002 21.7 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 EGR30598.1 - 1.8e-06 28.1 0.0 4.7e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR30598.1 - 1.6e-05 24.9 0.0 7.5e-05 22.8 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ubiquitin_2 PF14560.6 EGR30598.1 - 0.0014 19.1 1.1 0.0014 19.1 1.1 4.0 4 0 0 4 4 4 1 Ubiquitin-like domain Erf4 PF10256.9 EGR30598.1 - 0.027 14.6 10.2 0.68 10.1 0.1 5.1 3 1 0 4 4 4 0 Golgin subfamily A member 7/ERF4 family MFS_1 PF07690.16 EGR30599.1 - 1.7e-22 79.9 35.5 5.2e-15 55.2 16.0 3.2 3 0 0 3 3 3 3 Major Facilitator Superfamily Pkinase PF00069.25 EGR30601.1 - 1.4e-67 227.9 2.1 1.6e-67 227.7 2.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30601.1 - 9.8e-40 136.5 0.3 1.2e-39 136.2 0.3 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR30601.1 - 0.00034 19.5 0.0 0.00056 18.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR30601.1 - 0.00037 20.5 0.0 0.0054 16.7 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGR30601.1 - 0.0078 15.9 3.4 0.66 9.6 0.2 2.5 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGR30601.1 - 0.015 14.7 0.1 0.026 13.9 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGR30601.1 - 0.018 14.4 0.1 0.05 12.9 0.0 1.8 2 1 0 2 2 2 0 Kinase-like Minor_capsid_3 PF12691.7 EGR30602.1 - 0.0043 17.4 3.2 0.0051 17.2 1.3 2.1 2 0 0 2 2 2 1 Minor capsid protein from bacteriophage RPA_C PF08784.11 EGR30602.1 - 0.028 15.1 0.7 0.87 10.3 0.1 3.0 3 1 0 3 3 3 0 Replication protein A C terminal Shisa PF13908.6 EGR30603.1 - 1.8 8.8 6.8 2.4 8.4 6.8 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator MFS_1 PF07690.16 EGR30604.1 - 2e-05 23.7 12.0 3.9e-05 22.7 11.9 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EGR30604.1 - 0.0026 16.7 7.5 0.0026 16.7 7.5 1.9 1 1 1 2 2 2 1 MFS_1 like family SIMPL PF04402.14 EGR30605.1 - 7.3e-18 65.8 4.3 8.3e-18 65.6 4.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Nod1 PF17114.5 EGR30605.1 - 0.026 14.7 0.3 0.05 13.8 0.3 1.6 1 1 0 1 1 1 0 Gef2-related medial cortical node protein Nod1 p25-alpha PF05517.12 EGR30607.1 - 0.0069 16.6 2.4 0.0069 16.6 2.4 3.4 3 0 0 3 3 3 1 p25-alpha LRR_6 PF13516.6 EGR30607.1 - 0.025 14.6 10.2 17 5.8 0.1 5.6 5 0 0 5 5 5 0 Leucine Rich repeat LRR_4 PF12799.7 EGR30607.1 - 0.44 11.1 37.2 0.13 12.7 2.9 6.7 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) TRAM_LAG1_CLN8 PF03798.16 EGR30608.1 - 6.9e-22 78.2 22.3 6.9e-22 78.2 22.3 2.2 3 0 0 3 3 3 1 TLC domain MORN PF02493.20 EGR30611.1 - 2e-74 241.3 85.2 1.2e-06 28.1 0.4 13.3 13 0 0 13 13 13 13 MORN repeat DUF3048_C PF17479.2 EGR30611.1 - 0.00015 22.1 21.8 0.53 10.7 1.3 5.8 2 2 3 5 5 5 4 Protein of unknown function (DUF3048) C-terminal domain WD40 PF00400.32 EGR30612.1 - 4.2e-62 204.6 39.3 7.4e-05 23.4 0.0 25.7 27 0 0 27 27 27 13 WD domain, G-beta repeat HELP PF03451.14 EGR30612.1 - 5.4e-40 135.1 5.9 3.4e-21 74.9 0.3 3.7 3 0 0 3 3 3 3 HELP motif ANAPC4_WD40 PF12894.7 EGR30612.1 - 3e-29 101.1 11.9 0.012 15.9 0.0 16.5 8 5 9 18 18 18 8 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EGR30612.1 - 8.3e-09 34.4 0.1 1.2 7.6 0.0 6.1 6 1 1 7 7 7 4 Cytochrome D1 heme domain EF-hand_6 PF13405.6 EGR30612.1 - 8.5e-08 31.5 3.4 0.0046 16.8 0.2 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EGR30612.1 - 1.3e-07 30.6 3.9 0.0049 16.3 0.2 3.9 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 EGR30612.1 - 3.8e-06 27.3 3.9 0.0065 16.9 0.2 3.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGR30612.1 - 2.6e-05 24.0 2.6 0.054 13.3 0.8 3.0 2 0 0 2 2 2 2 EF-hand domain pair DUF4012 PF13196.6 EGR30613.1 - 0.21 12.1 0.0 0.26 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4012) Ras PF00071.22 EGR30614.1 - 4.6e-56 188.9 0.1 4.6e-56 188.9 0.1 1.6 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EGR30614.1 - 7.1e-36 123.1 0.1 7.1e-36 123.1 0.1 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR30614.1 - 4e-18 65.5 0.1 4e-18 65.5 0.1 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR30614.1 - 1.3e-06 28.4 0.2 3e-06 27.3 0.0 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGR30614.1 - 1.2e-05 25.3 0.1 0.22 11.4 0.1 2.6 2 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EGR30614.1 - 2e-05 24.1 0.1 2e-05 24.1 0.1 1.6 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGR30614.1 - 0.00031 20.4 0.0 0.0013 18.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGR30614.1 - 0.00043 19.8 0.0 0.016 14.7 0.0 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 EGR30614.1 - 0.0055 16.2 0.7 0.0088 15.5 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit TetR_C_16 PF17920.1 EGR30614.1 - 0.0056 16.9 0.0 0.0091 16.2 0.0 1.2 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain OMPdecase PF00215.24 EGR30614.1 - 0.035 13.7 0.1 0.037 13.6 0.1 1.1 1 0 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family TIR_2 PF13676.6 EGR30614.1 - 0.039 14.6 0.1 0.069 13.8 0.1 1.4 1 0 0 1 1 1 0 TIR domain DUF948 PF06103.11 EGR30616.1 - 0.0016 18.7 3.7 0.0027 17.9 3.7 1.5 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.21 EGR30616.1 - 0.0056 16.5 6.7 0.0056 16.5 6.7 1.7 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF16 PF01519.16 EGR30616.1 - 0.037 14.5 19.0 0.057 13.9 7.3 2.4 1 1 1 2 2 2 0 Protein of unknown function DUF16 YtxH PF12732.7 EGR30616.1 - 0.11 13.0 2.0 0.32 11.6 1.9 1.9 1 1 0 1 1 1 0 YtxH-like protein DUF5603 PF18231.1 EGR30616.1 - 0.17 12.2 2.3 5 7.5 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5603) TMPIT PF07851.13 EGR30616.1 - 0.71 9.1 6.9 0.94 8.7 6.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein DUF1664 PF07889.12 EGR30616.1 - 1.8 8.6 9.1 0.83 9.7 5.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 EGR30616.1 - 7.8 6.0 8.1 2.2 7.8 2.8 1.9 1 1 1 2 2 2 0 fzo-like conserved region Alg14 PF08660.11 EGR30618.1 - 1.6e-54 184.5 1.4 4e-51 173.4 0.1 2.1 2 0 0 2 2 2 2 Oligosaccharide biosynthesis protein Alg14 like DUF4909 PF16253.5 EGR30618.1 - 1.3 8.8 8.7 0.2 11.5 3.4 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4909) DUF3597 PF12200.8 EGR30619.1 - 0.00014 22.4 4.5 0.00032 21.3 3.5 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3597) ADIP PF11559.8 EGR30619.1 - 0.00076 19.6 17.2 0.00076 19.6 17.2 2.6 2 1 1 3 3 3 1 Afadin- and alpha -actinin-Binding Glyco_hydro_67C PF07477.12 EGR30619.1 - 0.017 14.7 5.5 0.11 12.0 0.2 2.4 1 1 0 2 2 2 0 Glycosyl hydrolase family 67 C-terminus UPF0242 PF06785.11 EGR30619.1 - 0.018 15.2 33.1 0.53 10.4 7.1 2.6 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Atg14 PF10186.9 EGR30619.1 - 0.063 12.3 20.8 0.028 13.5 18.7 1.5 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lebercilin PF15619.6 EGR30619.1 - 0.19 11.4 30.9 0.064 12.9 27.5 1.9 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease CC2-LZ PF16516.5 EGR30619.1 - 0.22 11.9 25.4 0.16 12.4 1.2 4.2 1 1 3 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF1664 PF07889.12 EGR30619.1 - 0.23 11.5 15.4 0.76 9.8 7.6 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Tropomyosin PF00261.20 EGR30619.1 - 0.25 10.7 29.6 0.042 13.2 10.1 3.2 1 1 2 3 3 3 0 Tropomyosin She9_MDM33 PF05546.11 EGR30619.1 - 0.32 10.8 19.5 0.36 10.6 1.1 3.3 1 1 2 3 3 3 0 She9 / Mdm33 family Vps5 PF09325.10 EGR30619.1 - 0.69 9.4 23.4 0.019 14.6 14.4 2.5 1 1 1 3 3 3 0 Vps5 C terminal like Spc7 PF08317.11 EGR30619.1 - 0.71 8.7 30.3 1.1 8.1 20.7 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Golgin_A5 PF09787.9 EGR30619.1 - 1.7 8.1 27.7 2.9 7.3 27.2 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 5 APG6_N PF17675.1 EGR30619.1 - 2.1 8.9 33.2 1.1 9.8 17.1 3.0 1 1 2 3 3 3 0 Apg6 coiled-coil region Exonuc_VII_L PF02601.15 EGR30619.1 - 2.3 7.7 21.5 6.3 6.3 21.5 1.7 1 1 0 1 1 1 0 Exonuclease VII, large subunit Baculo_PEP_C PF04513.12 EGR30619.1 - 2.5 8.1 13.1 0.22 11.6 6.0 2.6 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF5082 PF16888.5 EGR30619.1 - 3.3 8.0 30.2 8.1 6.7 10.6 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) DUF4407 PF14362.6 EGR30619.1 - 3.5 6.9 16.8 15 4.8 16.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF745 PF05335.13 EGR30619.1 - 3.6 7.3 20.4 0.46 10.2 11.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF745) DUF948 PF06103.11 EGR30619.1 - 4.8 7.5 9.2 0.68 10.2 3.2 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Aida_N PF08910.10 EGR30619.1 - 6.2 7.3 11.7 0.34 11.3 2.2 3.0 1 1 1 3 3 3 0 Aida N-terminus GARP PF16731.5 EGR30619.1 - 6.3 6.4 11.9 0.43 10.2 2.1 2.9 2 1 1 3 3 3 0 Glutamic acid/alanine-rich protein of Trypanosoma Macoilin PF09726.9 EGR30619.1 - 7.8 4.9 25.4 16 3.8 25.4 1.6 1 1 0 1 1 1 0 Macoilin family HIP1_clath_bdg PF16515.5 EGR30619.1 - 8.2 7.1 27.4 8.1 7.1 13.9 3.6 1 1 3 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 IFT57 PF10498.9 EGR30619.1 - 8.5 5.2 33.2 0.077 11.9 16.9 3.0 1 1 2 3 3 3 0 Intra-flagellar transport protein 57 DUF1515 PF07439.11 EGR30620.1 - 0.013 15.5 0.5 0.013 15.5 0.5 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1515) HALZ PF02183.18 EGR30620.1 - 0.02 15.1 8.2 1.2 9.5 1.8 3.5 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF4407 PF14362.6 EGR30620.1 - 7.1 5.9 30.8 1.2 8.5 14.5 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HMG_box PF00505.19 EGR30621.1 - 2e-20 73.0 7.8 2e-20 73.0 7.8 1.3 1 1 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGR30621.1 - 2.2e-11 44.2 4.9 3e-11 43.8 4.9 1.2 1 0 0 1 1 1 1 HMG-box domain Ccdc124 PF06244.12 EGR30621.1 - 0.00017 22.2 1.3 0.00017 22.2 1.3 2.0 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 DUF1033 PF06279.11 EGR30621.1 - 0.035 14.3 5.0 0.036 14.3 4.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1033) NDUFB10 PF10249.9 EGR30621.1 - 0.041 14.4 3.2 0.045 14.3 3.2 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 eIF-5_eIF-2B PF01873.17 EGR30622.1 - 9.2e-33 112.6 0.5 9.2e-33 112.6 0.5 2.1 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 EGR30622.1 - 3.2e-13 49.6 2.7 6.3e-13 48.7 1.4 2.2 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon BRAP2 PF07576.12 EGR30623.1 - 0.092 13.0 0.4 0.28 11.4 0.4 1.8 1 0 0 1 1 1 0 BRCA1-associated protein 2 dCMP_cyt_deam_1 PF00383.23 EGR30624.1 - 2.3e-10 40.3 1.5 3.2e-10 39.8 1.5 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGR30624.1 - 4.4e-10 39.4 0.3 5.4e-10 39.2 0.3 1.2 1 0 0 1 1 1 1 MafB19-like deaminase SNAD4 PF18750.1 EGR30624.1 - 1.7e-05 24.9 2.0 2.7e-05 24.2 2.0 1.3 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC2 PF18772.1 EGR30624.1 - 5e-05 23.4 0.9 7.1e-05 22.9 0.9 1.3 1 0 0 1 1 1 1 APOBEC2 NAD1 PF18778.1 EGR30624.1 - 0.00011 22.3 1.7 0.00015 21.9 1.7 1.3 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC3 PF18771.1 EGR30624.1 - 0.00018 21.7 1.9 0.00028 21.0 1.9 1.4 1 0 0 1 1 1 1 APOBEC3 APOBEC1 PF18769.1 EGR30624.1 - 0.00028 21.1 1.0 0.00052 20.2 1.0 1.4 1 0 0 1 1 1 1 APOBEC1 NAD2 PF18782.1 EGR30624.1 - 0.00045 20.4 1.1 0.00065 19.9 1.1 1.2 1 0 0 1 1 1 1 Novel AID APOBEC clade 2 APOBEC4_like PF18774.1 EGR30624.1 - 0.0033 17.4 2.4 0.0052 16.7 2.2 1.5 1 1 0 1 1 1 1 APOBEC4-like -AID/APOBEC-deaminase APOBEC_N PF08210.11 EGR30624.1 - 0.0053 16.7 0.6 0.0078 16.1 0.6 1.3 1 0 0 1 1 1 1 APOBEC-like N-terminal domain Bd3614-deam PF14439.6 EGR30624.1 - 0.27 11.3 2.2 0.68 10.0 2.2 1.7 1 1 0 1 1 1 0 Bd3614-like deaminase DUF4586 PF15239.6 EGR30625.1 - 2.5e-22 80.5 6.6 2.9e-22 80.2 6.6 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) ATP-synt_C PF00137.21 EGR30626.1 - 3.9e-35 120.0 35.4 3e-22 78.7 14.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C GerA PF03323.13 EGR30626.1 - 6.7 5.1 7.9 10 4.5 1.0 2.2 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein TPR_7 PF13176.6 EGR30627.1 - 0.0022 17.9 0.9 0.94 9.7 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGR30627.1 - 0.003 17.3 4.1 0.75 9.7 0.9 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGR30627.1 - 0.0067 16.5 1.8 0.5 10.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat EMP24_GP25L PF01105.24 EGR30628.1 - 2e-09 37.7 2.7 8.5e-09 35.6 2.7 1.7 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD CENP-K PF11802.8 EGR30628.1 - 0.0053 16.4 0.5 0.0069 16.0 0.5 1.1 1 0 0 1 1 1 1 Centromere-associated protein K Med9 PF07544.13 EGR30628.1 - 0.011 15.8 1.5 0.027 14.6 0.8 1.9 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Pkinase PF00069.25 EGR30629.1 - 7.7e-29 100.9 0.0 1.4e-28 100.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 EGR30629.1 - 3.2e-20 72.5 1.3 7e-11 42.6 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Pkinase_Tyr PF07714.17 EGR30629.1 - 1.5e-15 57.2 0.0 2.7e-15 56.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_4 PF13637.6 EGR30629.1 - 7.3e-14 51.9 0.5 3.4e-07 30.7 0.1 3.6 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGR30629.1 - 3.4e-12 46.3 0.1 2.1e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR30629.1 - 4e-12 45.2 0.3 0.0015 18.8 0.0 3.6 3 0 0 3 3 3 3 Ankyrin repeat RINGv PF12906.7 EGR30629.1 - 3.4e-11 43.1 11.0 3.4e-11 43.1 11.0 2.1 2 0 0 2 2 2 1 RING-variant domain Ank PF00023.30 EGR30629.1 - 1.5e-08 34.7 0.0 0.0015 18.9 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeat DUF3447 PF11929.8 EGR30629.1 - 0.026 14.5 1.8 0.27 11.2 1.7 2.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3447) DUF1754 PF08555.10 EGR30629.1 - 0.037 14.8 0.5 0.11 13.3 0.5 1.8 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) zf-RING_2 PF13639.6 EGR30629.1 - 2.9 8.3 11.3 17 5.8 11.4 2.3 1 1 1 2 2 2 0 Ring finger domain Carb_anhydrase PF00194.21 EGR30630.1 - 0.014 15.0 0.3 0.015 14.8 0.3 1.1 1 0 0 1 1 1 0 Eukaryotic-type carbonic anhydrase Pkinase PF00069.25 EGR30631.1 - 1.2e-15 57.6 0.3 2.7e-15 56.5 0.3 1.5 1 0 0 1 1 1 1 Protein kinase domain TPR_19 PF14559.6 EGR30631.1 - 1.2e-15 57.7 2.3 0.00018 22.0 0.1 5.4 5 1 1 6 6 5 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR30631.1 - 2.3e-15 56.6 31.2 1.1e-06 28.8 4.3 6.6 5 2 2 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 Pkinase_fungal PF17667.1 EGR30631.1 - 4.2e-10 39.0 0.1 7.2e-10 38.2 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase TPR_2 PF07719.17 EGR30631.1 - 1.3e-06 28.1 27.3 0.036 14.2 0.4 8.0 8 1 0 8 8 8 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGR30631.1 - 3.1e-06 27.5 0.0 11 7.2 0.0 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat Coatomer_E PF04733.14 EGR30631.1 - 5.8e-06 25.9 5.4 0.00049 19.6 2.7 3.8 2 2 1 3 3 3 1 Coatomer epsilon subunit PPR_2 PF13041.6 EGR30631.1 - 9.2e-06 25.8 0.1 0.12 12.6 0.0 4.2 4 0 0 4 4 3 1 PPR repeat family PPR PF01535.20 EGR30631.1 - 1.1e-05 25.3 0.0 0.38 11.1 0.0 5.4 5 0 0 5 5 5 1 PPR repeat TPR_6 PF13174.6 EGR30631.1 - 4e-05 24.0 2.2 1.6 9.5 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGR30631.1 - 0.00011 22.8 0.0 2.6 8.8 0.0 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat Pkinase_Tyr PF07714.17 EGR30631.1 - 0.00066 19.0 0.0 0.0013 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HrpB1_HrpK PF09613.10 EGR30631.1 - 0.0025 17.5 0.0 4.8 6.8 0.0 3.4 3 0 0 3 3 3 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_12 PF13424.6 EGR30631.1 - 0.0068 16.7 11.9 6.8 7.1 0.0 6.7 5 3 1 6 6 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGR30631.1 - 0.0072 16.4 0.0 0.07 13.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGR30631.1 - 0.16 12.1 8.0 3.3 7.9 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGR30631.1 - 3.1 7.8 29.1 1.9 8.4 0.7 7.8 9 0 0 9 9 9 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGR30631.1 - 7.7 6.7 14.8 2.8 8.1 0.8 5.2 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Filament PF00038.21 EGR30632.1 - 4.7 6.7 124.7 19 4.7 11.7 5.5 1 1 3 4 4 4 0 Intermediate filament protein YIF1 PF03878.15 EGR30633.1 - 1.6e-44 152.3 6.9 1.6e-44 152.3 6.9 1.3 2 0 0 2 2 2 1 YIF1 Yip1 PF04893.17 EGR30633.1 - 0.0013 18.4 5.5 0.002 17.9 5.5 1.2 1 0 0 1 1 1 1 Yip1 domain EMP70 PF02990.16 EGR30634.1 - 4.7e-85 286.2 13.6 4.7e-85 286.2 13.6 2.0 2 1 0 2 2 2 1 Endomembrane protein 70 Transket_pyr PF02779.24 EGR30634.1 - 6.6e-60 201.8 0.0 1.2e-59 200.9 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EGR30634.1 - 1.7e-50 171.6 0.0 2.6e-50 171.1 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EGR30634.1 - 1e-43 148.6 0.3 4.1e-43 146.7 0.3 2.0 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EGR30634.1 - 2.2e-13 49.6 1.5 5.7e-13 48.2 1.5 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus FA_desaturase PF00487.24 EGR30635.1 - 7.2e-22 78.4 17.0 9.7e-22 78.0 17.0 1.1 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.10 EGR30635.1 - 1.3e-10 40.6 3.8 2.2e-10 39.8 3.8 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) Phage_holin_4_2 PF04020.13 EGR30635.1 - 0.23 12.2 0.2 0.23 12.2 0.2 2.0 2 1 0 2 2 2 0 Mycobacterial 4 TMS phage holin, superfamily IV UQ_con PF00179.26 EGR30636.1 - 2.6e-29 101.7 0.1 3e-29 101.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGR30636.1 - 0.00015 22.0 0.3 0.0002 21.6 0.3 1.2 1 0 0 1 1 1 1 RWD domain UFC1 PF08694.11 EGR30636.1 - 0.0076 15.9 0.1 0.012 15.2 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 SelR PF01641.18 EGR30637.1 - 1.3e-41 141.4 0.3 1.5e-41 141.3 0.3 1.0 1 0 0 1 1 1 1 SelR domain zinc_ribbon_10 PF10058.9 EGR30637.1 - 0.0036 17.0 0.7 0.66 9.8 0.0 2.2 2 0 0 2 2 2 2 Predicted integral membrane zinc-ribbon metal-binding protein Endonuclease_7 PF02945.15 EGR30637.1 - 0.023 14.6 0.2 0.14 12.1 0.1 2.0 2 0 0 2 2 2 0 Recombination endonuclease VII Yippee-Mis18 PF03226.14 EGR30637.1 - 0.079 13.2 0.8 0.24 11.7 0.9 1.8 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ribosomal_L37e PF01907.19 EGR30637.1 - 0.23 11.7 1.5 5.1 7.3 0.1 2.2 2 0 0 2 2 2 0 Ribosomal protein L37e UQ_con PF00179.26 EGR30638.1 - 4.9e-38 129.9 0.7 5.5e-38 129.8 0.7 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGR30638.1 - 7e-05 23.1 0.1 9.6e-05 22.6 0.1 1.3 1 1 0 1 1 1 1 RWD domain RL10P_insert PF17777.1 EGR30639.1 - 7e-18 64.4 0.1 1.4e-17 63.4 0.1 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EGR30639.1 - 1.2e-14 54.2 1.1 1.7e-14 53.8 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L10 DUF243 PF03103.17 EGR30639.1 - 0.06 13.7 1.1 0.06 13.7 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF243) MFS_1 PF07690.16 EGR30640.1 - 1.4e-40 139.3 21.5 1.8e-36 125.8 9.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGR30640.1 - 4.8e-32 111.4 21.9 6.1e-32 111.1 21.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 EGR30640.1 - 0.053 11.9 0.0 0.089 11.2 0.0 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector MFS_4 PF06779.14 EGR30640.1 - 0.18 11.1 3.3 0.093 12.0 1.0 1.6 2 0 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB Pkinase PF00069.25 EGR30641.1 - 3.1e-75 252.9 1.1 5.2e-75 252.2 1.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30641.1 - 4e-48 164.0 0.2 6.2e-48 163.3 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EGR30641.1 - 7.2e-24 84.0 10.5 1.6e-12 47.7 0.3 3.6 4 1 0 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR30641.1 - 1.4e-23 80.7 5.3 2.8e-05 23.3 0.4 5.0 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGR30641.1 - 4e-20 70.0 9.0 5.8e-06 25.8 0.0 5.2 5 0 0 5 5 4 4 EF-hand domain EF-hand_5 PF13202.6 EGR30641.1 - 3.2e-18 64.3 13.5 3.3e-06 26.3 0.0 5.1 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 EGR30641.1 - 3.9e-16 58.6 8.7 8.5e-05 22.3 0.3 5.8 3 1 3 6 6 6 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGR30641.1 - 1.8e-11 44.3 3.7 3.4e-05 24.1 0.1 3.4 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.14 EGR30641.1 - 4.1e-06 26.3 0.9 1.9e-05 24.1 0.2 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_4 PF12763.7 EGR30641.1 - 1.9e-05 24.6 10.6 0.0021 18.0 0.3 3.7 3 1 1 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EGR30641.1 - 0.0036 17.1 3.6 4 7.4 0.0 4.5 4 0 0 4 4 4 1 EF hand Pkinase_fungal PF17667.1 EGR30641.1 - 0.0043 15.9 0.0 0.0071 15.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR30641.1 - 0.016 15.2 0.0 0.16 11.8 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Anoct_dimer PF16178.5 EGR30643.1 - 0.0051 16.6 1.5 0.0079 15.9 1.5 1.2 1 0 0 1 1 1 1 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Orthopox_F6 PF06601.12 EGR30643.1 - 1.6 8.9 7.0 0.33 11.2 2.7 2.2 2 1 0 2 2 2 0 Orthopoxvirus F6 protein Ribosomal_L5e PF17144.4 EGR30644.1 - 1.1e-77 259.6 1.7 2.1e-77 258.7 1.7 1.5 1 0 0 1 1 1 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EGR30644.1 - 4.3e-25 88.5 11.6 4.3e-25 88.5 11.6 2.3 2 1 0 2 2 2 1 Ribosomal L18 C-terminal region TIR PF01582.20 EGR30644.1 - 0.041 13.7 1.9 0.067 13.0 1.9 1.3 1 0 0 1 1 1 0 TIR domain Peptidase_M16_C PF05193.21 EGR30646.1 - 2.8e-20 73.1 1.7 5.4e-20 72.2 1.7 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGR30646.1 - 8.5e-05 22.6 0.4 0.00029 20.8 0.1 2.0 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Dynamin_M PF01031.20 EGR30647.1 - 1.9e-68 230.8 9.1 1e-67 228.4 3.7 2.8 2 1 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 EGR30647.1 - 5.7e-49 166.4 4.1 1.5e-48 165.0 0.2 2.5 2 0 0 2 2 2 1 Dynamin family GED PF02212.18 EGR30647.1 - 4.5e-20 71.6 2.1 7.8e-20 70.8 0.4 2.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGR30647.1 - 1.3e-05 25.2 0.3 9.3e-05 22.5 0.3 2.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EGR30647.1 - 0.0079 16.7 7.0 0.056 13.9 0.0 3.8 4 0 0 4 4 4 1 ABC transporter FeoB_N PF02421.18 EGR30647.1 - 0.013 15.1 0.3 6.7 6.2 0.0 2.7 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_28 PF13521.6 EGR30647.1 - 0.09 13.0 0.0 0.33 11.2 0.0 2.0 1 0 0 1 1 1 0 AAA domain MutS_III PF05192.18 EGR30647.1 - 0.29 11.4 2.4 3.6 7.8 2.4 2.4 1 1 0 1 1 1 0 MutS domain III Vps16_N PF04841.13 EGR30648.1 - 3.3e-34 118.3 10.0 7.2e-23 81.0 7.3 3.3 2 1 0 2 2 2 2 Vps16, N-terminal region LRR_6 PF13516.6 EGR30649.1 - 0.0017 18.2 23.9 0.79 9.9 0.5 7.5 7 0 0 7 7 7 4 Leucine Rich repeat CTP_transf_like PF01467.26 EGR30650.1 - 7.6e-37 126.7 0.0 8e-21 74.7 0.0 2.3 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 EGR30650.1 - 0.0015 18.4 1.2 1.4 8.8 0.2 3.0 3 0 0 3 3 3 2 FAD synthetase GDPD PF03009.17 EGR30651.1 - 2e-17 63.8 0.0 1.1e-15 58.1 0.0 2.2 1 1 1 2 2 2 2 Glycerophosphoryl diester phosphodiesterase family PI-PLC-X PF00388.19 EGR30651.1 - 0.0016 18.0 0.0 0.0052 16.4 0.0 1.7 1 1 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DUF4996 PF16387.5 EGR30651.1 - 0.099 13.1 0.8 0.77 10.3 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function SHIPPO-rpt PF07004.12 EGR30653.1 - 1e-40 136.8 57.7 1.4e-05 25.7 0.3 12.3 12 0 0 12 12 12 12 Sperm-tail PG-rich repeat ECR1_N PF14382.6 EGR30653.1 - 3.3e-06 26.8 0.3 1.6 8.6 0.0 6.1 7 1 1 8 8 8 3 Exosome complex exonuclease RRP4 N-terminal region PapD-like PF14874.6 EGR30654.1 - 0.02 15.0 0.1 0.04 14.1 0.1 1.5 1 0 0 1 1 1 0 Flagellar-associated PapD-like GAS PF13851.6 EGR30655.1 - 0.0058 16.0 7.7 0.0058 16.0 7.7 1.9 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DUF1192 PF06698.11 EGR30655.1 - 0.0077 16.3 8.1 1.3 9.2 0.2 3.5 3 1 0 3 3 3 1 Protein of unknown function (DUF1192) SlyX PF04102.12 EGR30655.1 - 0.013 16.1 10.3 0.014 16.0 6.8 2.6 1 1 1 2 2 2 0 SlyX tRNA-synt_1d PF00750.19 EGR30655.1 - 0.026 13.5 1.3 0.028 13.4 1.3 1.1 1 0 0 1 1 1 0 tRNA synthetases class I (R) THP2 PF09432.10 EGR30655.1 - 0.039 14.0 5.8 0.051 13.6 4.7 1.8 1 1 1 2 2 2 0 Tho complex subunit THP2 Mst1_SARAH PF11629.8 EGR30655.1 - 0.056 13.5 9.7 0.31 11.1 1.8 3.1 2 2 0 3 3 3 0 C terminal SARAH domain of Mst1 XLF PF09302.11 EGR30655.1 - 0.074 13.2 0.8 0.074 13.2 0.8 2.4 1 1 2 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component DUF4349 PF14257.6 EGR30655.1 - 0.079 12.4 0.9 0.13 11.7 0.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4349) Tropomyosin_1 PF12718.7 EGR30655.1 - 0.085 13.0 10.5 0.89 9.7 0.7 2.6 2 1 1 3 3 3 0 Tropomyosin like GrpE PF01025.19 EGR30655.1 - 0.095 12.4 6.7 1.2 8.8 0.3 2.4 1 1 1 2 2 2 0 GrpE HMMR_N PF15905.5 EGR30655.1 - 0.098 12.1 13.8 0.081 12.4 9.3 2.0 1 1 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal bZIP_1 PF00170.21 EGR30655.1 - 0.13 12.4 11.5 0.16 12.1 0.5 3.5 2 1 2 4 4 4 0 bZIP transcription factor TMF_DNA_bd PF12329.8 EGR30655.1 - 0.16 12.0 13.1 0.43 10.6 7.4 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding Zein-binding PF04576.15 EGR30655.1 - 0.19 12.1 7.3 2.2 8.6 0.2 2.8 2 1 0 3 3 3 0 Zein-binding BRE1 PF08647.11 EGR30655.1 - 0.21 11.7 9.3 2.2 8.4 2.2 2.6 1 1 2 3 3 3 0 BRE1 E3 ubiquitin ligase YabA PF06156.13 EGR30655.1 - 0.32 11.7 11.4 11 6.8 0.8 2.8 1 1 2 3 3 3 0 Initiation control protein YabA ZapB PF06005.12 EGR30655.1 - 0.43 11.1 14.6 9e+02 0.4 14.6 3.2 1 1 0 1 1 1 0 Cell division protein ZapB CENP-F_leu_zip PF10473.9 EGR30655.1 - 0.48 10.4 16.3 3.8 7.5 2.9 2.8 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bap31_Bap29_C PF18035.1 EGR30655.1 - 0.56 10.2 8.2 5.5 7.1 4.6 3.0 2 1 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DivIC PF04977.15 EGR30655.1 - 0.62 9.9 12.9 64 3.4 8.1 3.4 1 1 1 2 2 2 0 Septum formation initiator TMF_TATA_bd PF12325.8 EGR30655.1 - 0.68 10.2 12.2 13 6.0 3.8 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding K-box PF01486.17 EGR30655.1 - 0.77 10.0 12.6 1.1 9.5 8.4 2.8 2 1 0 2 2 2 0 K-box region Cep57_MT_bd PF06657.13 EGR30655.1 - 0.82 10.2 9.5 0.64 10.5 4.3 2.6 1 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Spc24 PF08286.11 EGR30655.1 - 0.9 9.8 10.4 7.3 6.9 5.4 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 HALZ PF02183.18 EGR30655.1 - 0.99 9.7 5.9 0.48 10.7 1.7 2.7 2 1 1 3 3 2 0 Homeobox associated leucine zipper KLRAQ PF10205.9 EGR30655.1 - 1 9.6 9.9 1.1 9.6 0.8 2.6 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein ATG16 PF08614.11 EGR30655.1 - 1.3 9.2 10.5 0.87 9.8 7.0 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Spc29 PF17082.5 EGR30655.1 - 1.9 8.2 9.9 5.6 6.7 9.9 1.8 1 1 0 1 1 1 0 Spindle Pole Component 29 FAM76 PF16046.5 EGR30655.1 - 2.4 7.4 8.4 3.4 6.9 4.4 2.0 1 1 1 2 2 2 0 FAM76 protein TSC22 PF01166.18 EGR30655.1 - 4.4 7.7 14.4 1 9.7 2.6 3.6 1 1 2 4 4 4 0 TSC-22/dip/bun family DUF16 PF01519.16 EGR30655.1 - 4.8 7.7 10.0 7.8 7.0 2.6 2.3 1 1 2 3 3 3 0 Protein of unknown function DUF16 UPF0242 PF06785.11 EGR30655.1 - 5.3 7.1 15.2 50 3.9 14.8 2.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF641 PF04859.12 EGR30655.1 - 6.2 7.2 10.8 4.6 7.6 0.8 2.9 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) RIH_assoc PF08454.11 EGR30656.1 - 2e-28 98.2 11.0 2e-28 98.2 11.0 8.8 5 3 4 9 9 9 1 RyR and IP3R Homology associated MIR PF02815.19 EGR30657.1 - 2.1e-10 40.8 0.5 2.1e-10 40.8 0.5 3.9 3 1 0 3 3 3 1 MIR domain RYDR_ITPR PF01365.21 EGR30657.1 - 2.4e-10 40.2 9.8 2.4e-10 40.2 9.8 7.0 4 3 2 6 6 6 1 RIH domain VitD-bind_III PF09164.10 EGR30657.1 - 0.12 12.4 1.6 10 6.2 0.3 3.1 2 0 0 2 2 2 0 Vitamin D binding protein, domain III Pepsin-I3 PF06394.13 EGR30657.1 - 4.2 7.6 14.1 0.049 13.8 2.1 3.7 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain G-patch PF01585.23 EGR30658.1 - 6.3e-11 42.0 0.1 1.1e-10 41.3 0.1 1.4 1 0 0 1 1 1 1 G-patch domain Catalase PF00199.19 EGR30659.1 - 2.5e-199 662.2 0.7 3.1e-199 661.9 0.7 1.1 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EGR30659.1 - 5.2e-22 77.8 0.2 1e-21 76.9 0.2 1.5 1 0 0 1 1 1 1 Catalase-related immune-responsive SOXp PF12336.8 EGR30659.1 - 0.087 13.9 0.0 0.31 12.1 0.0 1.9 2 0 0 2 2 2 0 SOX transcription factor DUF3078 PF11276.8 EGR30660.1 - 0.16 12.5 5.7 0.11 12.9 1.9 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3078) TPR_1 PF00515.28 EGR30661.1 - 0.0072 16.1 0.8 0.018 14.9 0.8 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGR30661.1 - 0.021 14.9 1.7 0.04 14.1 0.6 2.1 2 1 0 2 2 2 0 Tetratricopeptide repeat POC1 PF10450.9 EGR30661.1 - 0.64 9.0 4.8 0.13 11.2 0.8 1.7 2 0 0 2 2 2 0 POC1 chaperone Longin PF13774.6 EGR30662.1 - 4e-05 23.6 0.0 5.3e-05 23.2 0.0 1.3 1 1 0 1 1 1 1 Regulated-SNARE-like domain Asp PF00026.23 EGR30663.1 - 1.3e-60 205.4 3.3 2.7e-60 204.4 3.3 1.6 1 0 0 1 1 1 1 Eukaryotic aspartyl protease WD40 PF00400.32 EGR30663.1 - 1.1e-08 35.6 4.8 0.0075 17.1 0.0 4.0 3 0 0 3 3 3 2 WD domain, G-beta repeat TAXi_N PF14543.6 EGR30663.1 - 1.3e-07 32.0 0.1 0.00013 22.3 0.2 2.4 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGR30663.1 - 1.4e-05 25.7 0.1 0.00068 20.2 0.0 2.9 2 1 0 2 2 2 1 Aspartyl protease ANAPC4_WD40 PF12894.7 EGR30663.1 - 0.00017 21.8 0.3 0.12 12.6 0.1 4.1 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain gag-asp_proteas PF13975.6 EGR30663.1 - 0.0019 18.7 0.0 0.013 16.0 0.0 2.3 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease TAXi_C PF14541.6 EGR30663.1 - 0.0031 17.3 0.0 0.012 15.5 0.0 2.0 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Curto_V2 PF07325.11 EGR30663.1 - 0.011 15.5 0.1 0.39 10.6 0.0 2.4 2 0 0 2 2 2 0 Curtovirus V2 protein ThiF PF00899.21 EGR30664.1 - 2.9e-58 197.1 0.1 4.2e-58 196.6 0.1 1.2 1 0 0 1 1 1 1 ThiF family UBA_e1_thiolCys PF10585.9 EGR30664.1 - 1.3e-06 28.5 7.7 3.2e-05 24.0 0.9 4.3 3 2 1 4 4 4 2 Ubiquitin-activating enzyme active site Shikimate_DH PF01488.20 EGR30664.1 - 0.0068 16.5 0.4 0.027 14.6 0.0 2.2 3 0 0 3 3 3 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EGR30664.1 - 0.019 15.4 0.0 0.077 13.4 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding Sec23_helical PF04815.15 EGR30666.1 - 0.0081 16.0 0.3 0.027 14.3 0.3 1.8 1 0 0 1 1 1 1 Sec23/Sec24 helical domain ComA PF02679.15 EGR30666.1 - 0.044 13.3 0.2 0.062 12.8 0.2 1.2 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Pkinase PF00069.25 EGR30667.1 - 1.5e-65 221.2 3.0 1.5e-65 221.2 3.0 2.8 2 1 0 2 2 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30667.1 - 3.2e-31 108.6 1.6 5.4e-20 71.8 0.1 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase EF-hand_5 PF13202.6 EGR30667.1 - 1.4e-21 75.0 5.1 1.5e-05 24.2 0.1 6.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGR30667.1 - 3.5e-20 70.1 8.8 2.4e-05 23.9 0.1 6.5 5 0 0 5 5 4 3 EF-hand domain EF-hand_7 PF13499.6 EGR30667.1 - 4.6e-19 68.6 6.7 2.7e-09 37.3 0.5 3.9 2 1 0 3 3 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR30667.1 - 1.4e-17 61.8 4.8 2e-06 26.9 0.5 7.7 6 1 0 6 6 5 4 EF hand EF-hand_8 PF13833.6 EGR30667.1 - 4.4e-15 55.3 3.1 6.1e-06 26.0 0.1 4.8 2 1 2 4 4 4 4 EF-hand domain pair Kinase-like PF14531.6 EGR30667.1 - 1.7e-09 37.4 0.0 5.4e-09 35.8 0.0 1.9 1 1 0 1 1 1 1 Kinase-like SPARC_Ca_bdg PF10591.9 EGR30667.1 - 2.2e-06 27.9 0.4 2.2e-06 27.9 0.4 4.3 2 2 1 3 3 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.14 EGR30667.1 - 5.1e-06 26.0 0.3 1.4e-05 24.6 0.3 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR30667.1 - 0.00032 20.7 0.0 0.00048 20.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family CDC45 PF02724.14 EGR30667.1 - 0.18 10.1 24.7 0.29 9.4 24.7 1.3 1 0 0 1 1 1 0 CDC45-like protein tRNA-synt_1 PF00133.22 EGR30670.1 - 3.1e-63 214.0 6.9 4.5e-63 213.5 6.9 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EGR30670.1 - 2e-11 43.3 8.0 5e-06 25.5 2.7 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (M) LRR_6 PF13516.6 EGR30670.1 - 0.00018 21.3 22.3 1.4 9.2 0.0 8.4 9 1 0 9 9 9 3 Leucine Rich repeat LRR_4 PF12799.7 EGR30670.1 - 0.00047 20.5 39.9 0.15 12.6 5.1 8.1 7 1 1 8 8 8 4 Leucine Rich repeats (2 copies) DUF2064 PF09837.9 EGR30670.1 - 0.16 11.8 0.1 1.3 8.8 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2064) DUF4041 PF13250.6 EGR30670.1 - 5 7.1 8.8 0.54 10.2 0.9 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4041) Ribosomal_L30_N PF08079.12 EGR30672.1 - 1.1e-17 64.0 13.8 1.1e-17 64.0 13.8 2.2 2 0 0 2 2 2 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EGR30672.1 - 1.3e-16 60.2 1.7 3.6e-16 58.8 1.7 1.8 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Rpn3_C PF08375.11 EGR30672.1 - 0.76 10.2 0.1 0.76 10.2 0.1 2.7 3 1 0 3 3 3 0 Proteasome regulatory subunit C-terminal Synaptobrevin PF00957.21 EGR30672.1 - 6.7 6.6 7.0 13 5.6 7.0 1.5 1 1 0 1 1 1 0 Synaptobrevin RIH_assoc PF08454.11 EGR30673.1 - 7.1e-34 115.7 5.9 7.1e-34 115.7 5.9 4.4 2 1 1 3 3 3 1 RyR and IP3R Homology associated DTW PF03942.15 EGR30673.1 - 0.21 11.3 2.1 7 6.3 0.1 3.0 2 1 1 3 3 3 0 DTW domain MMtag PF10159.9 EGR30673.1 - 0.21 11.9 7.9 0.041 14.2 1.5 3.1 2 0 0 2 2 2 0 Multiple myeloma tumor-associated Chordopox_A13L PF05961.11 EGR30673.1 - 5.5 7.3 8.9 0.48 10.7 0.5 3.9 3 1 0 3 3 3 0 Chordopoxvirus A13L protein CTP_transf_1 PF01148.20 EGR30674.1 - 0.11 12.3 2.4 0.15 11.8 2.4 1.3 1 0 0 1 1 1 0 Cytidylyltransferase family Yae1_N PF09811.9 EGR30674.1 - 0.12 12.1 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Essential protein Yae1, N terminal Ins145_P3_rec PF08709.11 EGR30675.1 - 1.1e-15 57.4 20.1 4.1e-13 49.0 6.4 4.6 1 1 2 3 3 3 2 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 EGR30675.1 - 8.6e-13 48.5 16.2 2.6e-10 40.5 3.5 4.2 3 1 0 3 3 3 2 MIR domain DUF866 PF05907.13 EGR30676.1 - 1.3e-13 51.1 0.5 1.3e-13 51.1 0.5 1.9 2 1 0 2 2 2 1 Eukaryotic protein of unknown function (DUF866) CN_hydrolase PF00795.22 EGR30676.1 - 1.6e-13 50.6 0.0 2.2e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF2206 PF09971.9 EGR30677.1 - 0.0095 14.7 12.5 0.011 14.5 12.5 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2206) FBPase PF00316.20 EGR30678.1 - 5.9e-25 87.8 0.0 1.1e-24 86.9 0.0 1.4 2 0 0 2 2 2 1 Fructose-1-6-bisphosphatase, N-terminal domain HATPase_c PF02518.26 EGR30683.1 - 1.3e-20 73.9 0.1 2.6e-20 73.0 0.1 1.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGR30683.1 - 0.0034 17.2 0.0 0.0049 16.7 0.0 1.4 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF948 PF06103.11 EGR30684.1 - 3 8.1 10.3 0.4 11.0 5.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) WES_acyltransf PF03007.16 EGR30684.1 - 7.1 6.3 10.6 8.1 6.1 10.6 1.0 1 0 0 1 1 1 0 Wax ester synthase-like Acyl-CoA acyltransferase domain Ribosomal_L27A PF00828.19 EGR30685.1 - 1.4e-29 103.4 0.7 2.6e-29 102.5 0.7 1.5 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Choline_transpo PF04515.12 EGR30686.1 - 6.9e-77 258.8 45.6 6.9e-77 258.8 45.6 2.9 3 1 1 4 4 4 1 Plasma-membrane choline transporter DUF3188 PF11384.8 EGR30686.1 - 0.02 14.6 1.0 0.13 12.0 1.0 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) KBP_C PF12309.8 EGR30687.1 - 1.7e-52 179.2 18.9 3e-52 178.3 18.9 1.5 1 1 0 1 1 1 1 KIF-1 binding protein C terminal TPR_7 PF13176.6 EGR30687.1 - 0.012 15.6 5.8 1.5 9.0 0.1 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1664 PF07889.12 EGR30687.1 - 0.18 11.8 4.3 0.28 11.2 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3452 PF11934.8 EGR30687.1 - 0.34 10.4 5.4 1 8.9 1.4 3.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) TPR_2 PF07719.17 EGR30687.1 - 2.2 8.6 12.6 13 6.2 0.4 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGR30687.1 - 3.9 7.8 8.8 14 6.1 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGR30687.1 - 5.6 7.8 5.8 36 5.3 0.4 4.6 6 0 0 6 6 6 0 Tetratricopeptide repeat WD40 PF00400.32 EGR30688.1 - 1.3e-13 51.2 8.8 6.1e-05 23.7 0.1 6.6 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR30688.1 - 9.2e-10 38.7 2.2 0.0094 16.2 0.0 6.2 4 2 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain CTP_transf_like PF01467.26 EGR30689.1 - 1.8e-36 125.5 1.0 2.1e-17 63.6 0.0 2.8 3 0 0 3 3 3 2 Cytidylyltransferase-like FAD_syn PF06574.12 EGR30689.1 - 0.00014 21.8 2.5 0.45 10.4 0.0 4.3 3 1 0 4 4 4 2 FAD synthetase Pantoate_ligase PF02569.15 EGR30689.1 - 0.018 14.3 4.1 2.4 7.3 0.0 3.1 2 1 1 3 3 3 0 Pantoate-beta-alanine ligase TerB PF05099.13 EGR30689.1 - 0.072 13.0 1.2 0.13 12.2 1.2 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TerB Cation_ATPase_C PF00689.21 EGR30692.1 - 8.3e-40 136.4 13.6 8.3e-40 136.4 13.6 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGR30692.1 - 1.2e-37 129.2 2.3 1.2e-37 129.2 2.3 3.7 5 0 0 5 5 5 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 EGR30692.1 - 9.4e-11 41.3 0.1 9.3e-10 38.1 0.0 2.7 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 EGR30692.1 - 0.00032 21.0 0.3 0.00085 19.7 0.0 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 EGR30693.1 - 6.1e-73 245.4 0.3 7.4e-73 245.2 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30693.1 - 2.1e-38 132.1 0.0 2.8e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR30693.1 - 2.2e-07 30.5 0.0 6.8e-07 28.9 0.0 1.7 1 1 1 2 2 2 1 Kinase-like DUF3958 PF13125.6 EGR30693.1 - 1.2 9.3 4.6 0.65 10.2 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) TPP_enzyme_N PF02776.18 EGR30694.1 - 1.2e-07 31.5 0.0 1.6e-06 27.8 0.0 2.1 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EGR30694.1 - 0.0055 16.5 0.0 0.21 11.4 0.0 2.3 1 1 1 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain MVP_shoulder PF11978.8 EGR30694.1 - 0.04 13.9 0.0 5.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Shoulder domain Patched PF02460.18 EGR30695.1 - 1.3e-62 212.1 41.0 6.7e-35 120.4 15.4 3.2 2 2 1 3 3 3 3 Patched family Sterol-sensing PF12349.8 EGR30695.1 - 2e-37 128.4 9.8 2e-37 128.4 9.8 2.6 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation MMPL PF03176.15 EGR30695.1 - 0.0014 17.7 7.5 0.0014 17.7 7.5 1.8 2 0 0 2 2 2 1 MMPL family Muted PF14942.6 EGR30695.1 - 0.039 14.3 2.1 0.72 10.2 1.8 2.7 3 0 0 3 3 3 0 Organelle biogenesis, Muted-like protein Pkinase PF00069.25 EGR30696.1 - 1.9e-74 250.3 0.1 1.9e-74 250.3 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30696.1 - 2.8e-46 157.9 0.1 5.9e-46 156.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR30696.1 - 2.8e-05 23.6 0.0 5.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGR30696.1 - 2.9e-05 23.2 6.9 5.3e-05 22.3 6.9 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGR30696.1 - 0.052 12.3 1.9 0.14 11.0 1.9 1.7 1 1 0 1 1 1 0 Fungal protein kinase Chlam_PMP PF02415.17 EGR30697.1 - 0.71 10.5 2.1 38 5.1 0.5 2.9 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat NAPRTase_N PF17767.1 EGR30698.1 - 8.2e-33 113.5 0.9 9.6e-32 110.0 0.9 2.5 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase PF04095.16 EGR30698.1 - 1e-12 48.2 0.0 2.3e-11 43.8 0.0 2.2 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family NAPRTase_C PF17956.1 EGR30698.1 - 1.7e-12 47.7 1.0 4.2e-12 46.5 1.0 1.7 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain DUF5595 PF18077.1 EGR30698.1 - 0.013 15.5 0.0 0.065 13.3 0.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) QRPTase_N PF02749.16 EGR30698.1 - 0.046 13.8 0.0 0.26 11.4 0.0 2.2 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain CutA1 PF03091.15 EGR30698.1 - 0.1 12.4 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein Nsp1_C PF05064.13 EGR30698.1 - 4.7 7.1 7.2 3.5 7.5 0.0 2.9 3 0 0 3 3 3 0 Nsp1-like C-terminal region PNTB PF02233.16 EGR30700.1 - 1.3e-88 297.9 0.0 3.1e-88 296.7 0.0 1.6 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_N PF05222.15 EGR30700.1 - 3.1e-13 50.2 0.0 5.8e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain zf-CHCC PF10276.9 EGR30700.1 - 1.9e-11 43.8 0.2 4.2e-11 42.7 0.2 1.6 1 0 0 1 1 1 1 Zinc-finger domain zf-C2H2_3 PF13878.6 EGR30700.1 - 0.0072 16.1 0.8 0.015 15.2 0.8 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO VWA_2 PF13519.6 EGR30702.1 - 0.00012 22.7 0.2 0.00095 19.8 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain Vma12 PF11712.8 EGR30702.1 - 0.5 10.4 2.9 0.39 10.8 1.3 1.7 2 0 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DnaB PF00772.21 EGR30704.1 - 0.087 12.9 3.0 3.1 7.9 0.4 2.4 1 1 1 2 2 2 0 DnaB-like helicase N terminal domain Beta_helix PF13229.6 EGR30705.1 - 1.1e-32 113.1 56.5 1.7e-12 47.4 10.6 3.3 1 1 1 3 3 3 3 Right handed beta helix region NosD PF05048.13 EGR30705.1 - 3.4e-23 82.2 48.6 1e-08 34.8 13.6 3.7 1 1 2 3 3 3 3 Periplasmic copper-binding protein (NosD) DUF1565 PF07602.11 EGR30705.1 - 0.00012 21.6 43.3 0.0067 15.8 0.0 5.0 2 1 3 5 5 5 3 Protein of unknown function (DUF1565) PSII PF00421.19 EGR30705.1 - 0.096 11.4 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Photosystem II protein MotCF PF09158.10 EGR30705.1 - 0.89 9.6 7.0 0.53 10.4 0.7 3.2 3 0 0 3 3 3 0 Bacteriophage T4 MotA, C-terminal AhpC-TSA PF00578.21 EGR30706.1 - 4.1e-33 113.9 0.1 7.5e-33 113.1 0.0 1.5 2 0 0 2 2 2 1 AhpC/TSA family 1-cysPrx_C PF10417.9 EGR30706.1 - 3.3e-14 52.5 0.1 6.3e-14 51.5 0.1 1.5 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 EGR30706.1 - 1e-13 51.2 0.0 1.4e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 Redoxin SRP_TPR_like PF17004.5 EGR30708.1 - 0.11 12.6 1.2 0.16 12.0 1.2 1.3 1 1 0 1 1 1 0 Putative TPR-like repeat CTP_transf_1 PF01148.20 EGR30709.1 - 1.4e-36 126.6 8.8 1.6e-36 126.5 8.8 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family CarS-like PF01864.17 EGR30709.1 - 8.9e-05 22.5 2.9 9.2e-05 22.5 1.7 1.7 1 1 0 1 1 1 1 CDP-archaeol synthase Phage_holin_2_4 PF16082.5 EGR30709.1 - 0.23 11.2 0.0 0.43 10.4 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like Ribosomal_L36e PF01158.18 EGR30710.1 - 5e-31 106.8 9.1 5.6e-31 106.6 9.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e CAMSAP_CH PF11971.8 EGR30711.1 - 0.0004 20.2 2.4 0.054 13.3 0.8 2.5 2 0 0 2 2 2 2 CAMSAP CH domain Hpt PF01627.23 EGR30711.1 - 0.12 12.7 0.0 0.2 11.9 0.0 1.4 1 0 0 1 1 1 0 Hpt domain UNC-93 PF05978.16 EGR30712.1 - 2.2e-09 37.2 22.1 2.3e-08 33.9 20.2 2.9 1 1 1 2 2 2 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 EGR30712.1 - 2.4e-08 33.3 1.9 2.4e-08 33.3 1.9 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 EGR30712.1 - 0.0013 17.1 4.0 0.0013 17.1 4.0 1.6 1 1 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Pkinase PF00069.25 EGR30714.1 - 2.1e-70 237.1 3.0 2.1e-70 237.1 3.0 1.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30714.1 - 1.5e-47 162.1 0.6 2.7e-47 161.2 0.6 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR30714.1 - 1.3e-06 28.0 0.5 1.3e-06 28.0 0.5 2.2 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR30714.1 - 1.8e-06 27.0 0.8 1.4e-05 24.1 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGR30714.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DENN PF02141.21 EGR30714.1 - 0.67 9.9 4.5 5.9 6.8 0.1 2.3 2 0 0 2 2 2 0 DENN (AEX-3) domain DnaJ PF00226.31 EGR30715.1 - 3.6e-06 27.0 0.1 3.6e-06 27.0 0.1 3.3 3 1 1 4 4 4 1 DnaJ domain Pam16 PF03656.13 EGR30715.1 - 0.00034 20.6 0.6 0.00084 19.4 0.0 1.8 2 0 0 2 2 2 1 Pam16 DUF4623 PF15416.6 EGR30715.1 - 0.26 9.8 1.7 0.34 9.4 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4623) Ribosomal_L21e PF01157.18 EGR30716.1 - 1.1e-40 137.6 4.4 1.1e-40 137.6 4.4 1.8 2 0 0 2 2 2 1 Ribosomal protein L21e SpoIIE PF07228.12 EGR30717.1 - 2.8e-11 43.7 0.0 3.8e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EGR30717.1 - 0.0012 18.5 0.0 0.036 13.7 0.0 2.2 2 0 0 2 2 2 1 Protein phosphatase 2C DNA_pol3_delta2 PF13177.6 EGR30717.1 - 0.01 15.6 0.5 0.02 14.7 0.3 1.6 1 1 0 1 1 1 0 DNA polymerase III, delta subunit ATP-cone PF03477.16 EGR30717.1 - 0.081 13.5 0.4 0.23 12.1 0.2 1.8 1 1 1 2 2 2 0 ATP cone domain Abhydrolase_1 PF00561.20 EGR30718.1 - 7.6e-25 88.0 0.0 9.3e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGR30718.1 - 4.7e-20 71.9 0.0 5e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGR30718.1 - 3.6e-13 50.6 0.0 3.6e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family LIDHydrolase PF10230.9 EGR30718.1 - 8.5e-09 35.3 0.1 1e-08 35.1 0.1 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Chlorophyllase2 PF12740.7 EGR30718.1 - 1.3e-08 34.1 0.0 2.1e-08 33.4 0.0 1.4 1 1 0 1 1 1 1 Chlorophyllase enzyme Esterase PF00756.20 EGR30718.1 - 1.6e-08 34.5 0.0 2e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 EGR30718.1 - 4.9e-08 33.1 0.0 0.00035 20.4 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Thioesterase PF00975.20 EGR30718.1 - 1.6e-06 28.4 0.0 1.7e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_3 PF07859.13 EGR30718.1 - 9e-06 25.7 0.0 1.1e-05 25.4 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Ser_hydrolase PF06821.13 EGR30718.1 - 1.3e-05 25.1 0.0 2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase Chlorophyllase PF07224.11 EGR30718.1 - 3.2e-05 23.1 0.0 3.9e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyllase BAAT_C PF08840.11 EGR30718.1 - 3.4e-05 23.9 0.1 4.2e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.13 EGR30718.1 - 6e-05 22.9 0.0 6.9e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.7 EGR30718.1 - 0.00037 20.3 0.0 0.00053 19.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 EGR30718.1 - 0.00051 18.8 0.0 0.00054 18.7 0.0 1.2 1 0 0 1 1 1 1 Ndr family Peptidase_S9 PF00326.21 EGR30718.1 - 0.0015 18.1 0.0 0.0023 17.4 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF915 PF06028.11 EGR30718.1 - 0.0019 17.6 1.0 0.35 10.2 0.3 2.4 2 1 0 2 2 2 2 Alpha/beta hydrolase of unknown function (DUF915) Lipase_3 PF01764.25 EGR30718.1 - 0.003 17.4 0.2 0.015 15.1 0.0 2.0 1 1 1 2 2 2 1 Lipase (class 3) DUF3530 PF12048.8 EGR30718.1 - 0.0068 15.9 0.0 0.009 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Peptidase_S28 PF05577.12 EGR30718.1 - 0.012 14.5 0.0 0.02 13.7 0.0 1.4 1 1 0 1 1 1 0 Serine carboxypeptidase S28 DUF1749 PF08538.10 EGR30718.1 - 0.014 14.5 0.0 0.018 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) DUF1057 PF06342.12 EGR30718.1 - 0.02 13.9 0.0 0.024 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF1057) UPF0227 PF05728.12 EGR30718.1 - 0.031 14.2 0.0 0.04 13.9 0.0 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF711 PF05167.12 EGR30719.1 - 0.12 11.2 0.2 0.2 10.5 0.2 1.4 1 0 0 1 1 1 0 Uncharacterised ACR (DUF711) DUF123 PF01986.16 EGR30719.1 - 5.7 7.5 6.3 1.7 9.2 2.9 1.9 2 1 0 2 2 2 0 Domain of unknown function DUF123 Nitroreductase PF00881.24 EGR30719.1 - 6.7 6.7 7.9 0.67 10.0 2.2 2.0 2 0 0 2 2 2 0 Nitroreductase family DUF3371 PF11851.8 EGR30720.1 - 1.8 9.7 4.9 3.7 8.7 4.9 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3371) Lon_C PF05362.13 EGR30721.1 - 7.7e-42 143.2 0.2 6.3e-41 140.2 0.0 2.1 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 EGR30721.1 - 9.3e-16 58.5 0.0 2.6e-15 57.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EGR30721.1 - 4.1e-10 40.0 0.1 2.4e-09 37.5 0.0 2.4 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGR30721.1 - 1.2e-06 28.6 0.0 3.5e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 EGR30721.1 - 2.9e-06 27.1 0.2 7.1e-06 25.9 0.1 1.7 2 0 0 2 2 1 1 Subunit ChlI of Mg-chelatase TIP49 PF06068.13 EGR30721.1 - 8.8e-06 25.1 0.1 2.1e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 EGR30721.1 - 1.1e-05 25.2 0.0 4.1e-05 23.4 0.0 2.1 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGR30721.1 - 6.1e-05 23.5 0.1 0.00023 21.6 0.1 2.0 1 1 1 2 2 1 1 AAA ATPase domain AAA_PrkA PF08298.11 EGR30721.1 - 0.00017 20.6 0.1 0.00043 19.3 0.1 1.6 1 0 0 1 1 1 1 PrkA AAA domain AAA_14 PF13173.6 EGR30721.1 - 0.00025 21.1 4.0 0.00026 21.0 0.0 2.9 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EGR30721.1 - 0.00042 20.1 0.0 0.00077 19.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 EGR30721.1 - 0.00051 20.3 0.1 0.14 12.5 0.1 2.8 2 1 0 3 3 2 1 AAA domain AAA_30 PF13604.6 EGR30721.1 - 0.00062 19.5 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EGR30721.1 - 0.00086 19.3 0.1 0.022 14.7 0.0 2.6 2 1 0 2 2 2 1 NACHT domain RNA_helicase PF00910.22 EGR30721.1 - 0.00098 19.5 0.1 0.0049 17.2 0.1 2.4 1 1 0 1 1 1 1 RNA helicase AAA_11 PF13086.6 EGR30721.1 - 0.0018 18.1 0.0 0.0041 17.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 EGR30721.1 - 0.0025 17.1 0.0 0.0055 16.0 0.0 1.6 1 1 0 1 1 1 1 KAP family P-loop domain AAA_7 PF12775.7 EGR30721.1 - 0.0033 17.0 0.0 0.013 15.1 0.0 2.0 1 0 0 1 1 1 1 P-loop containing dynein motor region Torsin PF06309.11 EGR30721.1 - 0.0035 17.4 0.0 0.0083 16.2 0.0 1.6 1 0 0 1 1 1 1 Torsin AAA_24 PF13479.6 EGR30721.1 - 0.0042 16.8 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGR30721.1 - 0.0051 17.2 0.0 0.013 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGR30721.1 - 0.0052 17.3 0.1 0.028 15.0 0.0 2.3 2 0 0 2 2 1 1 AAA domain ATPase_2 PF01637.18 EGR30721.1 - 0.0069 16.3 1.7 0.63 9.9 0.0 3.1 2 1 1 3 3 2 1 ATPase domain predominantly from Archaea DNA_pol3_delta2 PF13177.6 EGR30721.1 - 0.0077 16.0 0.3 2.1 8.1 0.2 2.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit PIF1 PF05970.14 EGR30721.1 - 0.0089 15.2 0.1 0.022 13.9 0.1 1.6 1 0 0 1 1 1 1 PIF1-like helicase KTI12 PF08433.10 EGR30721.1 - 0.0091 15.5 0.0 0.024 14.1 0.0 1.6 1 0 0 1 1 1 1 Chromatin associated protein KTI12 TsaE PF02367.17 EGR30721.1 - 0.011 15.7 0.0 0.04 13.9 0.0 1.9 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EGR30721.1 - 0.013 15.5 0.0 0.053 13.4 0.0 2.1 1 0 0 1 1 1 0 Rad17 P-loop domain Mg_chelatase PF01078.21 EGR30721.1 - 0.016 14.6 0.0 0.039 13.3 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGR30721.1 - 0.02 14.8 0.0 0.05 13.5 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Parvo_NS1 PF01057.17 EGR30721.1 - 0.023 13.8 0.0 0.049 12.7 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 EGR30721.1 - 0.027 14.2 0.0 0.069 12.9 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EGR30721.1 - 0.028 14.6 0.0 0.11 12.6 0.0 2.1 1 0 0 1 1 1 0 Sigma-54 interaction domain NB-ARC PF00931.22 EGR30721.1 - 0.037 13.2 0.0 0.089 12.0 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain ABC_tran PF00005.27 EGR30721.1 - 0.042 14.3 0.3 0.19 12.2 0.0 2.3 2 0 0 2 2 1 0 ABC transporter ResIII PF04851.15 EGR30721.1 - 0.053 13.5 0.1 0.053 13.5 0.1 2.5 3 0 0 3 3 1 0 Type III restriction enzyme, res subunit APS_kinase PF01583.20 EGR30721.1 - 0.074 12.9 0.0 0.25 11.2 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase RuBisCO_small PF00101.20 EGR30721.1 - 0.076 13.0 2.1 0.13 12.3 0.8 2.1 2 0 0 2 2 1 0 Ribulose bisphosphate carboxylase, small chain NTPase_1 PF03266.15 EGR30721.1 - 0.077 12.9 0.2 0.21 11.5 0.1 1.9 1 1 0 1 1 1 0 NTPase AAA_33 PF13671.6 EGR30721.1 - 0.1 12.7 0.0 0.19 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EGR30721.1 - 0.11 12.0 0.5 0.4 10.1 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein Zeta_toxin PF06414.12 EGR30721.1 - 0.12 11.6 0.0 0.21 10.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin ATP-synt_ab PF00006.25 EGR30722.1 - 2.4e-72 243.1 0.0 4.4e-72 242.2 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EGR30722.1 - 5.9e-48 162.4 2.1 6.1e-48 162.3 1.0 1.6 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EGR30722.1 - 1.1e-16 61.1 3.9 2.8e-16 59.8 3.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 EGR30722.1 - 2.7e-05 24.2 1.8 7.9e-05 22.7 1.8 1.8 1 0 0 1 1 1 1 HAS barrel domain MMR_HSR1_Xtn PF16897.5 EGR30723.1 - 3.3e-41 139.6 4.0 6.6e-41 138.6 4.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EGR30723.1 - 8.6e-21 74.1 1.0 1.4e-20 73.5 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 EGR30723.1 - 1.4e-15 57.1 0.0 2.5e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EGR30723.1 - 2.8e-10 39.9 0.0 6.1e-10 38.8 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGR30723.1 - 1.7e-05 25.0 3.3 0.026 14.6 0.0 3.0 2 1 1 3 3 3 2 Dynamin family DNA_pol_A PF00476.20 EGR30723.1 - 0.0046 16.1 0.9 0.0061 15.7 0.1 1.6 2 0 0 2 2 2 1 DNA polymerase family A RsgA_GTPase PF03193.16 EGR30723.1 - 0.038 13.9 1.2 0.28 11.1 0.0 2.8 2 1 1 3 3 3 0 RsgA GTPase RNase_PH_C PF03725.15 EGR30723.1 - 0.084 12.9 0.2 0.23 11.5 0.2 1.7 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 DUF1192 PF06698.11 EGR30724.1 - 0.32 11.1 4.6 0.28 11.3 1.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) RRM_1 PF00076.22 EGR30725.1 - 2.4e-15 56.1 0.9 4.8e-15 55.1 0.9 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 EGR30725.1 - 5.6e-05 23.0 17.4 0.0048 16.9 3.4 2.7 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_4 PF14392.6 EGR30725.1 - 0.00011 21.8 7.3 0.088 12.6 1.1 2.7 2 0 0 2 2 2 2 Zinc knuckle RRM_5 PF13893.6 EGR30725.1 - 0.0016 18.0 0.1 0.003 17.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGR30725.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif ASH PF15780.5 EGR30726.1 - 4e-06 26.9 6.9 0.26 11.5 0.0 7.8 9 0 0 9 9 9 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin DUF1573 PF07610.11 EGR30726.1 - 0.00013 21.9 2.9 2 8.5 0.0 5.7 4 1 0 4 4 4 2 Protein of unknown function (DUF1573) PapD-like PF14874.6 EGR30726.1 - 0.06 13.5 0.1 62 3.8 0.0 4.3 4 0 0 4 4 4 0 Flagellar-associated PapD-like DNA_pol_B PF00136.21 EGR30727.1 - 3.7e-22 78.7 0.3 4.3e-22 78.5 0.3 1.2 1 0 0 1 1 1 1 DNA polymerase family B Rpp20 PF12328.8 EGR30727.1 - 0.0017 18.3 0.2 0.0023 17.9 0.2 1.2 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P PhoLip_ATPase_C PF16212.5 EGR30728.1 - 2.3e-55 188.0 34.0 2.3e-55 188.0 34.0 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGR30728.1 - 3.9e-21 74.5 1.1 1.5e-20 72.6 1.1 2.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGR30728.1 - 1.4e-12 47.5 0.2 3.4e-11 43.1 0.0 2.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGR30728.1 - 3.6e-09 37.2 1.5 0.00073 19.9 1.3 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGR30728.1 - 0.026 14.0 0.0 0.22 11.0 0.0 2.6 2 1 0 2 2 2 0 E1-E2 ATPase Pkinase PF00069.25 EGR30729.1 - 2.6e-17 63.1 0.0 3.1e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30729.1 - 1.5e-05 24.4 0.0 4.9e-05 22.7 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase TrmO_C PF18389.1 EGR30729.1 - 0.091 12.9 0.5 0.19 11.9 0.5 1.4 1 0 0 1 1 1 0 TrmO C-terminal domain ASH PF15780.5 EGR30730.1 - 5e-15 55.5 0.7 0.024 14.8 0.0 7.3 6 1 1 7 7 7 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 EGR30730.1 - 3.8e-11 43.0 0.0 0.0001 22.4 0.0 3.9 4 0 0 4 4 4 2 Flagellar-associated PapD-like Motile_Sperm PF00635.26 EGR30730.1 - 5.5e-09 35.9 7.2 0.0048 16.7 0.2 5.2 5 0 0 5 5 5 3 MSP (Major sperm protein) domain DUF1573 PF07610.11 EGR30730.1 - 5.2e-05 23.2 9.5 0.86 9.7 0.4 6.8 5 3 0 5 5 5 2 Protein of unknown function (DUF1573) CARDB PF07705.11 EGR30730.1 - 0.3 11.4 2.2 51 4.2 0.1 4.9 6 0 0 6 6 6 0 CARDB DUF5001 PF16392.5 EGR30730.1 - 5.3 7.0 9.6 41 4.2 0.1 5.1 6 1 0 6 6 6 0 Ig-like domain HECT PF00632.25 EGR30732.1 - 1e-85 287.9 5.1 1e-85 287.9 5.1 1.7 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Sigma54_activ_2 PF14532.6 EGR30732.1 - 0.41 10.8 2.3 0.66 10.1 0.1 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain ABC2_membrane PF01061.24 EGR30734.1 - 2.6e-40 138.1 20.7 2.6e-40 138.1 20.7 1.5 2 0 0 2 2 2 1 ABC-2 type transporter MORN PF02493.20 EGR30734.1 - 3.9e-35 117.7 52.1 1.9e-07 30.6 0.5 9.1 9 0 0 9 9 9 8 MORN repeat ABC_tran PF00005.27 EGR30734.1 - 3.5e-10 40.5 0.2 1.1e-09 39.0 0.2 1.8 1 1 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGR30734.1 - 0.00077 18.7 45.6 0.00077 18.7 45.6 2.6 1 1 1 2 2 2 1 ABC-2 family transporter protein DarA_N PF18788.1 EGR30734.1 - 0.52 10.4 3.5 1.5 9.0 1.2 2.9 2 1 0 2 2 2 0 Defence against restriction A N-terminal UCH PF00443.29 EGR30735.1 - 2e-13 50.4 4.0 2e-13 50.4 4.0 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase TPR_12 PF13424.6 EGR30736.1 - 4.1e-09 36.6 2.7 0.00054 20.2 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGR30736.1 - 1e-08 34.7 10.5 0.016 15.3 0.6 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGR30736.1 - 1.1e-06 28.2 13.5 0.008 16.0 0.9 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGR30736.1 - 0.00033 20.4 1.6 1.9 8.4 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGR30736.1 - 0.0052 16.7 6.4 9.6 6.5 0.0 4.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGR30736.1 - 0.02 15.1 8.8 0.43 10.9 0.3 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 EGR30736.1 - 0.38 10.9 4.3 1 9.5 0.5 3.1 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain RPN7 PF10602.9 EGR30736.1 - 0.55 9.9 4.4 2.1 8.1 0.3 2.8 2 1 0 2 2 2 0 26S proteasome subunit RPN7 DUF4685 PF15737.5 EGR30736.1 - 1.5 9.3 6.1 0.32 11.5 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4685) Mito_carr PF00153.27 EGR30737.1 - 1.4e-50 169.2 3.5 6.1e-22 77.3 0.1 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 EGR30738.1 - 8.2e-52 176.2 1.7 8.2e-52 176.2 1.7 1.8 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30738.1 - 2.6e-39 135.1 0.7 2.6e-39 135.1 0.7 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR30738.1 - 1.2e-06 27.6 0.1 3.9e-06 25.9 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGR30738.1 - 4.3e-05 23.0 1.0 5.4e-05 22.6 0.0 1.8 2 0 0 2 2 2 1 Kinase-like bZIP_Maf PF03131.17 EGR30738.1 - 0.0002 21.8 8.0 0.0002 21.8 8.0 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF2661 PF10860.8 EGR30738.1 - 0.65 10.1 5.9 0.1 12.7 0.5 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF2661) Kinesin PF00225.23 EGR30739.1 - 2.4e-57 194.4 12.9 3.5e-57 193.8 12.1 1.8 1 1 1 2 2 2 1 Kinesin motor domain GTP_EFTU PF00009.27 EGR30739.1 - 1.7e-05 24.4 7.6 5e-05 22.9 0.2 3.3 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGR30739.1 - 0.0003 20.9 0.7 0.059 13.5 0.0 3.1 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 EGR30739.1 - 0.0058 16.9 4.7 0.13 12.5 0.1 3.4 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Pox_A3L PF05288.11 EGR30739.1 - 0.025 14.6 0.2 0.1 12.6 0.2 2.1 1 0 0 1 1 1 0 Poxvirus A3L Protein AAA_22 PF13401.6 EGR30739.1 - 0.027 14.7 0.3 0.83 9.9 0.0 3.3 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 EGR30739.1 - 0.23 12.0 0.0 0.23 12.0 0.0 3.0 3 1 0 3 3 3 0 ABC transporter DivIC PF04977.15 EGR30740.1 - 0.012 15.4 4.8 0.012 15.4 4.8 8.8 5 3 4 9 9 9 0 Septum formation initiator DUF4381 PF14316.6 EGR30741.1 - 0.11 12.7 3.1 0.15 12.3 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TTL PF03133.15 EGR30742.1 - 6.8e-56 189.5 11.8 6.8e-56 189.5 11.8 2.1 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR30742.1 - 1.2e-10 41.1 3.1 1.1e-07 31.3 0.0 2.5 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR30742.1 - 0.00093 18.5 2.2 0.01 15.1 0.1 2.4 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp EF-hand_7 PF13499.6 EGR30743.1 - 1.7e-12 47.6 1.0 2.1e-12 47.3 1.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGR30743.1 - 1.7e-11 42.8 4.7 5e-06 25.7 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGR30743.1 - 3.3e-11 42.2 0.8 0.00025 20.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGR30743.1 - 5.8e-11 41.4 3.7 1.3e-05 24.5 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGR30743.1 - 1.7e-07 30.9 2.6 6.5e-06 25.9 1.4 2.2 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGR30743.1 - 0.0066 16.7 1.8 0.026 14.8 1.4 1.9 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EGR30743.1 - 0.033 14.0 3.0 0.12 12.3 0.0 2.6 2 1 1 3 3 3 0 EF hand SapB_1 PF05184.15 EGR30743.1 - 0.058 13.4 1.4 0.058 13.4 1.4 2.5 3 0 0 3 3 3 0 Saposin-like type B, region 1 Phage_TAC_12 PF12363.8 EGR30743.1 - 0.073 13.5 4.3 0.3 11.5 4.3 1.9 1 1 0 1 1 1 0 Phage tail assembly chaperone protein, TAC AAA_2 PF07724.14 EGR30744.1 - 2.4e-36 125.4 0.3 2.2e-27 96.3 0.1 2.8 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 EGR30744.1 - 3.9e-16 59.7 0.2 1.5e-07 31.9 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGR30744.1 - 2.9e-09 37.1 0.0 1.4e-05 25.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGR30744.1 - 6.4e-06 26.5 0.1 0.00056 20.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EGR30744.1 - 1.7e-05 24.2 0.3 4.4e-05 22.8 0.1 1.8 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 EGR30744.1 - 2.4e-05 23.8 0.0 0.0013 18.2 0.0 2.9 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGR30744.1 - 0.00018 21.7 0.0 0.00064 19.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain MCM PF00493.23 EGR30744.1 - 0.00034 19.8 0.0 0.16 11.1 0.0 2.5 2 0 0 2 2 2 1 MCM P-loop domain Sigma54_activat PF00158.26 EGR30744.1 - 0.0004 20.1 0.0 0.032 13.9 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_16 PF13191.6 EGR30744.1 - 0.00058 20.3 0.1 0.0028 18.1 0.0 2.1 2 1 0 2 2 1 1 AAA ATPase domain AAA_18 PF13238.6 EGR30744.1 - 0.0006 20.4 2.9 0.00083 19.9 0.0 2.4 3 0 0 3 3 2 1 AAA domain RuvB_N PF05496.12 EGR30744.1 - 0.00081 19.2 0.1 0.53 10.0 0.0 2.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain ClpB_D2-small PF10431.9 EGR30744.1 - 0.002 18.2 0.1 0.002 18.2 0.1 3.1 4 0 0 4 4 3 1 C-terminal, D2-small domain, of ClpB protein Zeta_toxin PF06414.12 EGR30744.1 - 0.0032 16.8 0.0 0.0068 15.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_19 PF13245.6 EGR30744.1 - 0.004 17.5 0.0 0.0099 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain DEAD PF00270.29 EGR30744.1 - 0.0053 16.5 0.1 0.26 11.0 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Cytidylate_kin PF02224.18 EGR30744.1 - 0.0093 15.7 0.2 0.04 13.7 0.0 2.0 2 0 0 2 2 2 1 Cytidylate kinase AAA_8 PF12780.7 EGR30744.1 - 0.016 14.6 0.1 0.056 12.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 T2SSE PF00437.20 EGR30744.1 - 0.022 13.8 0.0 0.044 12.9 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein CPT PF07931.12 EGR30744.1 - 0.026 14.4 0.0 0.08 12.8 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein RNA_helicase PF00910.22 EGR30744.1 - 0.032 14.6 0.1 2.5 8.6 0.0 2.8 2 0 0 2 2 2 0 RNA helicase IstB_IS21 PF01695.17 EGR30744.1 - 0.033 13.9 0.1 0.3 10.8 0.0 2.5 3 0 0 3 3 2 0 IstB-like ATP binding protein PduV-EutP PF10662.9 EGR30744.1 - 0.034 13.9 0.1 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ResIII PF04851.15 EGR30744.1 - 0.042 13.9 2.2 0.81 9.7 0.0 2.8 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_28 PF13521.6 EGR30744.1 - 0.042 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain IPT PF01745.16 EGR30744.1 - 0.044 13.2 0.0 0.079 12.3 0.0 1.4 1 0 0 1 1 1 0 Isopentenyl transferase SRP54 PF00448.22 EGR30744.1 - 0.044 13.4 0.2 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TsaE PF02367.17 EGR30744.1 - 0.053 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EGR30744.1 - 0.069 12.7 0.0 0.22 11.0 0.0 1.9 2 0 0 2 2 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EGR30744.1 - 0.07 12.8 0.8 0.22 11.2 0.0 2.1 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGR30744.1 - 0.084 13.4 1.6 0.099 13.2 0.4 1.9 2 1 0 2 2 1 0 ABC transporter NACHT PF05729.12 EGR30744.1 - 0.1 12.5 0.3 1.3 8.9 0.0 2.6 3 0 0 3 3 2 0 NACHT domain Ribosomal_L22 PF00237.19 EGR30744.1 - 0.24 11.7 5.4 9.5 6.5 0.3 3.2 3 0 0 3 3 3 0 Ribosomal protein L22p/L17e Spore_YhaL PF14147.6 EGR30744.1 - 0.5 10.1 2.2 7.5 6.3 0.3 2.5 2 0 0 2 2 2 0 Sporulation protein YhaL AAA_17 PF13207.6 EGR30744.1 - 1.1 9.6 3.7 4.9 7.6 0.2 3.6 3 1 1 4 4 4 0 AAA domain A_thal_3526 PF09713.10 EGR30744.1 - 2.2 8.6 4.8 17 5.8 0.2 3.6 3 0 0 3 3 3 0 Plant protein 1589 of unknown function (A_thal_3526) tRNA-synt_1b PF00579.25 EGR30745.1 - 1e-20 74.3 0.1 2.7e-20 72.9 0.0 1.7 1 1 1 2 2 2 1 tRNA synthetases class I (W and Y) LRR_4 PF12799.7 EGR30746.1 - 3e-12 46.5 31.6 3.9e-08 33.5 6.5 5.5 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGR30746.1 - 1.4e-08 34.4 28.1 2.7e-06 27.0 9.4 3.8 3 0 0 3 3 3 2 Leucine rich repeat LRR_9 PF14580.6 EGR30746.1 - 1e-06 28.4 7.1 1e-06 28.4 7.1 3.8 3 2 1 4 4 4 1 Leucine-rich repeat LRR_1 PF00560.33 EGR30746.1 - 0.11 13.1 21.8 38 5.4 0.1 7.0 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 EGR30746.1 - 0.83 9.9 17.2 15 5.9 0.7 6.1 5 1 0 5 5 5 0 Leucine Rich repeat DUF1619 PF07773.11 EGR30747.1 - 0.072 13.0 5.8 0.091 12.7 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1619) Lactamase_B PF00753.27 EGR30751.1 - 5.6e-18 65.7 0.0 7.7e-18 65.2 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGR30751.1 - 1.6e-08 34.3 0.0 2.2e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 EGR30751.1 - 4.6e-07 29.7 0.1 1.2e-06 28.4 0.1 1.7 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain Lactamase_B_3 PF13483.6 EGR30751.1 - 0.0061 16.5 0.0 0.0091 15.9 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain YchF-GTPase_C PF06071.13 EGR30752.1 - 1.7e-40 137.0 0.3 4.2e-40 135.8 0.3 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EGR30752.1 - 2.7e-21 75.8 0.0 1.3e-20 73.6 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGR30752.1 - 8.2e-06 25.4 0.0 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 EGR30752.1 - 0.024 13.6 0.0 0.065 12.2 0.0 1.6 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EGR30752.1 - 0.077 13.5 0.0 0.38 11.3 0.0 2.1 2 1 0 2 2 2 0 AAA domain NUC153 PF08159.12 EGR30754.1 - 2.2e-11 43.4 0.4 5.7e-11 42.0 0.4 1.8 1 0 0 1 1 1 1 NUC153 domain WD40 PF00400.32 EGR30754.1 - 2.1e-10 41.0 0.0 0.00057 20.6 0.0 4.6 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR30754.1 - 5.6e-06 26.6 0.0 0.23 11.8 0.0 3.8 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Crystall PF00030.19 EGR30757.1 - 8.9e-07 29.0 0.1 3e-06 27.4 0.1 1.9 1 0 0 1 1 1 1 Beta/Gamma crystallin Toxin_17 PF08086.11 EGR30757.1 - 0.0083 16.4 50.7 0.094 13.0 3.5 5.7 5 0 0 5 5 5 5 Ergtoxin family UreD PF01774.17 EGR30757.1 - 0.014 15.3 0.0 1.9e+02 1.8 0.0 4.7 5 0 0 5 5 5 0 UreD urease accessory protein RAMA PF18755.1 EGR30757.1 - 0.04 14.3 5.8 3.9 7.9 0.1 4.4 5 0 0 5 5 5 0 Restriction Enzyme Adenine Methylase Associated TadF PF16964.5 EGR30757.1 - 0.14 11.9 24.7 1 9.1 2.9 5.2 5 0 0 5 5 5 0 Putative tight adherence pilin protein F PTPlike_phytase PF14566.6 EGR30757.1 - 0.24 11.5 9.4 0.63 10.2 0.3 2.6 2 0 0 2 2 2 0 Inositol hexakisphosphate QRPTase_C PF01729.19 EGR30757.1 - 0.86 9.4 6.3 3 7.6 0.3 3.6 4 1 1 5 5 5 0 Quinolinate phosphoribosyl transferase, C-terminal domain Clathrin PF00637.20 EGR30758.1 - 1.6e-07 31.3 44.2 0.018 14.9 0.1 8.5 4 2 2 8 8 8 4 Region in Clathrin and VPS TPR_19 PF14559.6 EGR30758.1 - 6e-07 29.9 17.3 0.2 12.2 0.1 7.0 6 2 1 7 7 6 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR30758.1 - 7.2e-06 26.1 21.4 1.8 8.9 0.0 8.2 6 3 3 9 9 9 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EGR30758.1 - 5.7e-05 23.7 3.7 40 5.0 0.0 5.9 4 1 1 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.32 EGR30758.1 - 0.0002 22.1 0.4 2.2 9.3 0.0 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR30758.1 - 0.005 17.1 2.5 9.3 6.6 0.0 4.2 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PPR_2 PF13041.6 EGR30758.1 - 0.005 17.0 2.4 0.31 11.3 0.4 4.6 5 0 0 5 5 5 1 PPR repeat family TPR_14 PF13428.6 EGR30758.1 - 0.006 17.3 14.3 24 6.1 0.1 8.1 7 2 3 10 10 7 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGR30758.1 - 0.0095 16.2 23.9 0.47 10.8 0.2 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGR30758.1 - 0.032 14.3 43.0 0.88 9.8 0.7 9.4 10 1 0 10 10 9 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGR30758.1 - 0.036 13.9 36.8 0.19 11.6 0.7 8.8 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGR30758.1 - 0.12 12.4 19.3 3.7 7.8 0.0 7.5 7 1 1 8 8 8 0 Tetratricopeptide repeat Ubiq-assoc PF09145.10 EGR30758.1 - 0.78 9.8 5.1 6.7 6.8 0.1 3.8 3 0 0 3 3 3 0 Ubiquitin-associated YfdX PF10938.8 EGR30758.1 - 2.4 8.1 10.4 0.19 11.7 0.1 3.7 5 0 0 5 5 5 0 YfdX protein L27_N PF09060.10 EGR30758.1 - 7.3 6.7 8.5 9.8 6.3 0.0 3.7 3 0 0 3 3 3 0 L27_N LMBR1 PF04791.16 EGR30759.1 - 7.7e-27 94.4 12.2 1.3e-26 93.6 12.2 1.3 1 0 0 1 1 1 1 LMBR1-like membrane protein Asp-Al_Ex PF06826.12 EGR30759.1 - 0.037 13.8 0.2 0.059 13.2 0.2 1.2 1 0 0 1 1 1 0 Predicted Permease Membrane Region UL41A PF17591.2 EGR30760.1 - 0.39 10.8 2.0 0.74 9.9 0.2 2.1 2 0 0 2 2 2 0 Herpesvirus UL41A Iso_dh PF00180.20 EGR30761.1 - 1.9e-75 254.2 0.0 2.2e-75 254.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Metallophos PF00149.28 EGR30763.1 - 8.2e-38 131.0 0.1 1e-37 130.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGR30763.1 - 9.6e-19 67.6 3.0 1.8e-18 66.7 3.0 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Pkinase PF00069.25 EGR30764.1 - 6.4e-66 222.4 0.2 6.4e-66 222.4 0.2 2.5 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30764.1 - 3.5e-45 154.3 0.1 9.4e-45 152.9 0.1 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR30764.1 - 0.00022 21.3 0.0 0.0017 18.3 0.1 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family TCTP PF00838.17 EGR30765.1 - 1.3e-52 178.5 6.2 1.4e-52 178.4 6.2 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein RhoGEF PF00621.20 EGR30765.1 - 0.048 13.9 0.1 0.056 13.7 0.1 1.2 1 0 0 1 1 1 0 RhoGEF domain Methyltransf_4 PF02390.17 EGR30766.1 - 1.3e-45 155.0 0.0 1.8e-45 154.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EGR30766.1 - 2.9e-05 24.7 0.0 8.2e-05 23.2 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGR30766.1 - 0.00054 19.8 0.2 0.0018 18.1 0.2 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGR30766.1 - 0.0011 19.6 0.0 0.0059 17.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGR30766.1 - 0.0083 15.7 0.0 0.022 14.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain DOT1 PF08123.13 EGR30766.1 - 0.0088 15.6 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_11 PF08241.12 EGR30766.1 - 0.018 15.7 0.0 0.053 14.2 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.7 EGR30766.1 - 0.022 14.7 0.0 0.84 9.6 0.0 2.3 1 1 1 2 2 2 0 Methyltransferase domain ATP-synt_C PF00137.21 EGR30767.1 - 2.3e-25 88.7 28.5 1e-13 51.4 13.5 2.1 2 0 0 2 2 2 2 ATP synthase subunit C DUF3180 PF11377.8 EGR30767.1 - 0.043 13.9 4.3 0.035 14.2 2.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3180) G0-G1_switch_2 PF15103.6 EGR30767.1 - 0.082 13.3 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 G0/G1 switch protein 2 SLC35F PF06027.12 EGR30767.1 - 0.19 11.2 5.6 0.92 9.0 0.7 2.1 1 1 1 2 2 2 0 Solute carrier family 35 Oxidored_q2 PF00420.24 EGR30767.1 - 0.68 9.6 6.4 0.27 10.9 0.8 2.5 1 1 2 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L TPR_12 PF13424.6 EGR30769.1 - 0.39 11.0 6.4 2 8.8 0.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TTL PF03133.15 EGR30770.1 - 3.1e-61 207.1 9.7 3.1e-61 207.1 9.7 2.7 2 1 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR30770.1 - 1.9e-05 24.0 0.0 1.9e-05 24.0 0.0 3.8 4 0 0 4 4 4 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR30770.1 - 0.0067 15.7 0.0 0.0067 15.7 0.0 2.3 2 1 0 2 2 2 1 Sugar-transfer associated ATP-grasp APC1_C PF18122.1 EGR30770.1 - 0.13 12.2 4.1 0.35 10.8 4.1 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain PARG_cat PF05028.14 EGR30771.1 - 1e-96 324.2 5.5 1.4e-96 323.8 5.5 1.1 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) TTL PF03133.15 EGR30772.1 - 6.9e-41 140.3 19.3 9.9e-41 139.8 12.8 3.0 1 1 1 3 3 3 2 Tubulin-tyrosine ligase family ANAPC15 PF15243.6 EGR30772.1 - 0.35 11.3 13.2 0.97 9.9 13.2 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 Rtf2 PF04641.12 EGR30772.1 - 0.52 9.6 15.5 2.6 7.3 0.1 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger Oxysterol_BP PF01237.18 EGR30773.1 - 1.2e-121 406.1 0.5 2e-121 405.3 0.5 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 EGR30773.1 - 2e-12 47.5 0.4 9.9e-12 45.3 0.4 2.3 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EGR30773.1 - 3e-07 30.6 0.1 8.1e-07 29.2 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EGR30773.1 - 0.011 16.1 3.3 0.53 10.7 2.9 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain ASH PF15780.5 EGR30774.1 - 3e-24 85.1 12.0 0.0084 16.3 0.0 10.5 11 1 0 11 11 11 8 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 EGR30774.1 - 2.2e-09 37.1 39.7 0.004 17.0 0.8 10.8 11 2 1 12 12 12 5 MSP (Major sperm protein) domain PapD-like PF14874.6 EGR30774.1 - 5.1e-08 33.0 0.1 0.32 11.2 0.0 5.0 5 0 0 5 5 5 3 Flagellar-associated PapD-like Skp1 PF01466.19 EGR30775.1 - 3.3e-10 39.9 0.1 6.4e-10 39.0 0.1 1.5 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EGR30775.1 - 3.6e-05 23.9 0.2 7.7e-05 22.8 0.2 1.6 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain Phage_int_SAM_5 PF13102.6 EGR30775.1 - 0.0099 16.2 0.7 0.072 13.4 0.0 2.4 1 1 1 2 2 2 1 Phage integrase SAM-like domain AAA PF00004.29 EGR30776.1 - 5.4e-43 146.6 0.0 1.2e-42 145.5 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGR30776.1 - 3.4e-08 33.1 0.2 7.1e-08 32.1 0.2 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EGR30776.1 - 2.9e-07 30.7 0.0 1.1e-06 28.8 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 EGR30776.1 - 3.7e-07 30.0 0.0 7.9e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 EGR30776.1 - 1.2e-06 28.9 0.1 0.01 16.1 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 EGR30776.1 - 6.8e-06 26.6 0.7 0.0029 18.0 0.0 3.2 2 1 1 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 EGR30776.1 - 2e-05 24.4 0.0 4.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_OB_N PF17758.1 EGR30776.1 - 3.5e-05 23.4 0.0 0.00011 21.8 0.0 1.8 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain AAA_5 PF07728.14 EGR30776.1 - 0.00014 21.9 0.1 0.00064 19.7 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) DUF815 PF05673.13 EGR30776.1 - 0.00022 20.4 0.0 0.00043 19.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_3 PF07726.11 EGR30776.1 - 0.00062 19.6 0.2 0.11 12.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGR30776.1 - 0.0018 18.3 0.2 0.0055 16.7 0.0 1.8 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EGR30776.1 - 0.0021 17.4 0.6 0.0064 15.7 0.0 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_33 PF13671.6 EGR30776.1 - 0.0027 17.8 0.0 0.0055 16.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGR30776.1 - 0.0028 17.4 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EGR30776.1 - 0.0029 18.0 0.0 0.0081 16.5 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 EGR30776.1 - 0.0034 17.9 0.1 0.011 16.3 0.0 2.1 2 1 0 2 2 1 1 AAA domain AAA_25 PF13481.6 EGR30776.1 - 0.01 15.4 0.4 0.43 10.1 0.1 2.5 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.22 EGR30776.1 - 0.016 14.4 0.1 0.45 9.7 0.0 2.8 3 0 0 3 3 3 0 NB-ARC domain AAA_24 PF13479.6 EGR30776.1 - 0.017 14.8 0.2 0.08 12.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGR30776.1 - 0.018 14.4 0.0 0.035 13.5 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EGR30776.1 - 0.022 15.0 0.6 0.043 14.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain PhoH PF02562.16 EGR30776.1 - 0.035 13.6 0.1 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein AAA_17 PF13207.6 EGR30776.1 - 0.037 14.5 0.6 0.12 12.8 0.0 2.2 2 0 0 2 2 1 0 AAA domain ATPase PF06745.13 EGR30776.1 - 0.046 13.1 0.1 0.98 8.7 0.1 2.5 1 1 1 2 2 2 0 KaiC AAA_7 PF12775.7 EGR30776.1 - 0.054 13.0 0.0 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region ATPase_2 PF01637.18 EGR30776.1 - 0.088 12.7 1.4 1.3 8.9 0.1 3.0 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EGR30776.1 - 0.089 13.3 0.4 0.3 11.6 0.1 2.1 2 2 0 2 2 1 0 ABC transporter TsaE PF02367.17 EGR30776.1 - 0.095 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 EGR30776.1 - 0.12 12.3 0.1 0.5 10.3 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.6 EGR30776.1 - 0.13 12.0 0.2 0.38 10.4 0.2 1.8 1 1 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.17 EGR30776.1 - 0.14 11.2 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 EGR30776.1 - 0.32 10.8 4.5 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain LMBR1 PF04791.16 EGR30777.1 - 3.9e-37 128.3 38.5 3.9e-37 128.3 38.5 3.2 2 1 0 2 2 2 1 LMBR1-like membrane protein Aminotran_4 PF01063.19 EGR30778.1 - 4.3e-26 92.2 0.0 7.8e-26 91.3 0.0 1.5 1 0 0 1 1 1 1 Amino-transferase class IV ADH_zinc_N PF00107.26 EGR30778.1 - 5.2e-13 49.1 0.1 9.6e-13 48.2 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DAGK_cat PF00781.24 EGR30778.1 - 4.4e-10 39.3 0.0 1.1e-09 38.0 0.0 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain ADH_N PF08240.12 EGR30778.1 - 4.8e-08 32.8 0.0 3.1e-07 30.2 0.0 2.1 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGR30778.1 - 0.002 19.2 0.0 0.0057 17.7 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase EIIA-man PF03610.16 EGR30778.1 - 0.2 11.9 0.6 3.1 8.1 0.2 2.7 2 1 0 2 2 2 0 PTS system fructose IIA component Ras PF00071.22 EGR30779.1 - 2.1e-45 154.2 0.2 2.9e-45 153.8 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR30779.1 - 2.4e-27 95.5 0.0 4.2e-27 94.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR30779.1 - 4.4e-13 49.1 0.7 5.7e-13 48.7 0.7 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGR30779.1 - 0.00015 21.2 0.2 0.0002 20.8 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGR30779.1 - 0.01 15.4 0.0 0.022 14.3 0.0 1.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGR30779.1 - 0.04 13.8 0.4 2.3 8.1 0.2 2.2 2 0 0 2 2 2 0 RsgA GTPase HTH_9 PF08221.11 EGR30779.1 - 0.057 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain P3A PF08727.11 EGR30779.1 - 0.064 12.7 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Poliovirus 3A protein like AMP-binding PF00501.28 EGR30780.1 - 6.7e-15 54.6 0.0 7.8e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme FHA PF00498.26 EGR30781.1 - 2.8e-21 75.6 0.0 8.2e-10 38.9 0.1 3.3 3 1 0 3 3 3 2 FHA domain Yop-YscD_cpl PF16697.5 EGR30781.1 - 1e-05 25.7 0.1 0.095 13.0 0.1 4.0 3 1 1 4 4 4 2 Inner membrane component of T3SS, cytoplasmic domain NIF PF03031.18 EGR30782.1 - 5e-05 23.1 0.1 5.8e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Ribosomal_L19e PF01280.20 EGR30783.1 - 5.4e-58 195.2 11.9 5.4e-58 195.2 11.9 1.5 2 0 0 2 2 2 1 Ribosomal protein L19e S4 PF01479.25 EGR30783.1 - 0.17 11.6 2.3 0.74 9.6 0.0 2.7 2 1 1 3 3 3 0 S4 domain CDC50 PF03381.15 EGR30785.1 - 1.1e-62 212.1 9.8 1.1e-62 212.1 9.8 1.6 2 0 0 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Ras PF00071.22 EGR30785.1 - 2.4e-13 50.0 0.2 5e-11 42.5 0.1 2.5 1 1 1 2 2 2 2 Ras family Roc PF08477.13 EGR30785.1 - 2.6e-10 40.5 0.7 1.3e-09 38.3 0.1 2.5 2 1 1 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR30785.1 - 4.7e-06 26.2 0.1 1.1e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family SH3_13 PF18335.1 EGR30785.1 - 8.3e-05 22.3 0.6 0.00034 20.4 0.3 2.2 2 0 0 2 2 2 1 ATP-dependent RecD-like DNA helicase SH3 domain Pkinase PF00069.25 EGR30786.1 - 1.1e-58 198.7 0.2 1.1e-58 198.7 0.2 1.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30786.1 - 1.8e-39 135.6 0.0 2.6e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR30786.1 - 0.022 13.7 0.1 0.036 13.0 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain RIO1 PF01163.22 EGR30786.1 - 0.034 13.8 0.1 0.061 12.9 0.1 1.4 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EGR30786.1 - 0.043 13.1 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kinase-PolyVal PF18762.1 EGR30786.1 - 0.07 13.1 0.6 0.14 12.1 0.0 1.8 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins PHR PF08005.12 EGR30786.1 - 0.09 13.5 0.1 2.4 8.8 0.0 2.5 3 0 0 3 3 3 0 PHR domain APH PF01636.23 EGR30786.1 - 0.2 11.5 0.0 1.3 8.9 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family PBP1_TM PF14812.6 EGR30787.1 - 0.15 12.4 0.1 0.46 10.9 0.1 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Phage_holin_6_1 PF09682.10 EGR30787.1 - 6.7 7.2 12.6 8.8 6.8 0.4 3.7 3 0 0 3 3 3 0 Bacteriophage holin of superfamily 6 (Holin_LLH) Peptidase_M24 PF00557.24 EGR30788.1 - 6.5e-45 153.4 0.0 8.9e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 EGR30788.1 - 4.1e-43 147.3 4.1 8e-43 146.3 4.1 1.5 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 EGR30788.1 - 2.2e-17 62.9 0.4 2.2e-17 62.9 0.4 3.0 3 0 0 3 3 3 1 C-terminal region of peptidase_M24 Peptidase_M20 PF01546.28 EGR30789.1 - 1.9e-17 63.7 0.0 2.3e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGR30789.1 - 4.4e-09 36.2 0.0 7.7e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Pkinase PF00069.25 EGR30790.1 - 2.3e-52 177.9 1.3 3.4e-52 177.4 1.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30790.1 - 3e-32 111.9 1.1 3.1e-32 111.9 0.2 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase HATPase_c PF02518.26 EGR30790.1 - 2e-21 76.6 0.7 4.7e-21 75.4 0.7 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Haspin_kinase PF12330.8 EGR30790.1 - 4.1e-08 32.6 1.8 7e-08 31.8 1.8 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGR30790.1 - 1.4e-07 31.1 0.1 2.1e-07 30.5 0.1 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR30790.1 - 1.6e-05 24.4 0.2 2.5e-05 23.7 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family HATPase_c_3 PF13589.6 EGR30790.1 - 0.00034 20.5 1.3 0.00086 19.2 1.2 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase_fungal PF17667.1 EGR30790.1 - 0.0009 18.1 0.0 0.0014 17.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR30790.1 - 0.0027 17.7 0.0 0.0039 17.1 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGR30790.1 - 0.037 13.6 1.6 0.074 12.7 1.6 1.5 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Adeno_PV PF03910.13 EGR30790.1 - 0.19 10.4 0.1 0.28 9.9 0.1 1.1 1 0 0 1 1 1 0 Adenovirus minor core protein PV Furin-like_2 PF15913.5 EGR30791.1 - 0.17 12.1 60.8 0.13 12.4 23.3 3.9 1 1 3 4 4 4 0 Furin-like repeat, cysteine-rich VSP PF03302.13 EGR30792.1 - 4e-05 22.7 18.3 4e-05 22.7 18.3 4.1 1 1 3 4 4 4 1 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EGR30792.1 - 0.63 10.2 80.9 0.031 14.4 25.2 4.7 2 2 1 3 3 3 0 Furin-like repeat, cysteine-rich DEAD PF00270.29 EGR30794.1 - 2.3e-43 148.0 0.0 6.9e-43 146.4 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR30794.1 - 3.3e-22 78.9 0.0 3.3e-22 78.9 0.0 3.4 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGR30794.1 - 1.1e-15 57.6 0.1 2.9e-15 56.2 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) DUF1003 PF06210.11 EGR30794.1 - 0.00068 19.7 1.0 0.00068 19.7 1.0 3.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1003) AAA_22 PF13401.6 EGR30794.1 - 0.052 13.8 2.4 0.079 13.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain WD40 PF00400.32 EGR30797.1 - 3.8e-45 151.0 55.1 4.3e-06 27.4 0.1 21.5 22 1 1 23 23 21 12 WD domain, G-beta repeat HELP PF03451.14 EGR30797.1 - 6.1e-37 125.3 0.5 2.9e-21 75.1 0.0 3.5 3 0 0 3 3 3 3 HELP motif ANAPC4_WD40 PF12894.7 EGR30797.1 - 5.3e-20 71.5 14.8 0.013 15.8 0.0 12.9 9 3 5 15 15 14 5 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EGR30797.1 - 6.1e-13 48.0 0.5 0.0055 15.3 0.0 6.6 5 1 1 6 6 6 4 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 EGR30797.1 - 5.2e-05 22.5 0.9 0.061 12.4 0.1 3.3 3 0 0 3 3 3 2 Coatomer WD associated region Nucleoporin_N PF08801.11 EGR30797.1 - 0.00013 20.9 3.8 0.023 13.5 0.4 3.9 4 0 0 4 4 4 2 Nup133 N terminal like VID27 PF08553.10 EGR30797.1 - 0.001 18.2 0.1 0.26 10.3 0.0 3.9 4 0 0 4 4 4 1 VID27 C-terminal WD40-like domain PQQ_3 PF13570.6 EGR30797.1 - 0.0011 19.3 1.1 30 5.3 0.0 5.8 5 0 0 5 5 5 0 PQQ-like domain BBS2_Mid PF14783.6 EGR30797.1 - 0.0056 16.7 1.2 4.1 7.5 0.0 5.2 5 1 0 6 6 6 1 Ciliary BBSome complex subunit 2, middle region Lactonase PF10282.9 EGR30797.1 - 0.0092 15.3 0.0 0.13 11.5 0.0 2.5 2 0 0 2 2 2 1 Lactonase, 7-bladed beta-propeller EF-hand_6 PF13405.6 EGR30797.1 - 0.23 11.5 2.1 5.1 7.3 0.1 3.8 3 0 0 3 3 3 0 EF-hand domain EF-hand_1 PF00036.32 EGR30797.1 - 1.3 8.7 4.2 2 8.2 0.2 3.5 3 0 0 3 3 3 0 EF hand Ribosomal_L32e PF01655.18 EGR30799.1 - 4.1e-47 159.1 0.3 5.2e-47 158.7 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 DUF1908 PF08926.11 EGR30800.1 - 0.0066 15.6 1.0 0.0075 15.4 1.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1908) YfdX PF10938.8 EGR30800.1 - 0.092 12.7 0.1 0.11 12.4 0.1 1.1 1 0 0 1 1 1 0 YfdX protein Cpn60_TCP1 PF00118.24 EGR30801.1 - 1.3e-44 152.7 4.5 4.6e-44 150.9 4.5 1.7 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family MGAT2 PF05060.14 EGR30801.1 - 0.15 11.1 0.3 0.27 10.3 0.3 1.3 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) Pkinase PF00069.25 EGR30802.1 - 3.9e-75 252.6 0.3 5.3e-75 252.2 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30802.1 - 3.1e-37 128.3 0.0 4.3e-37 127.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Dynein_light PF01221.18 EGR30802.1 - 1.6e-05 25.2 0.1 1.6e-05 25.2 0.1 2.3 2 1 0 2 2 2 1 Dynein light chain type 1 Kinase-like PF14531.6 EGR30802.1 - 0.0025 17.2 0.7 0.0064 15.8 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR30802.1 - 0.0055 15.5 0.0 0.009 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_C PF00433.24 EGR30802.1 - 0.026 15.2 0.0 0.045 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein kinase C terminal domain YrbL-PhoP_reg PF10707.9 EGR30802.1 - 0.028 13.9 0.1 0.053 13.0 0.1 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 EGR30802.1 - 0.16 11.9 0.0 8 6.3 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Syntaxin-6_N PF09177.11 EGR30803.1 - 0.0026 18.3 4.8 0.0026 18.3 4.8 6.2 3 2 1 5 5 5 4 Syntaxin 6, N-terminal ERM PF00769.19 EGR30803.1 - 2 8.2 96.2 0.17 11.7 8.9 4.9 1 1 4 5 5 5 0 Ezrin/radixin/moesin family Sec1 PF00995.23 EGR30804.1 - 5e-97 326.5 28.1 5.6e-97 326.3 28.1 1.0 1 0 0 1 1 1 1 Sec1 family Ribosomal_L22 PF00237.19 EGR30804.1 - 0.86 9.9 4.3 2.1 8.6 2.3 2.5 2 0 0 2 2 2 0 Ribosomal protein L22p/L17e Pkinase PF00069.25 EGR30805.1 - 2.4e-70 236.9 0.0 3.5e-70 236.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30805.1 - 3e-39 134.9 0.0 4.6e-39 134.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Myosin_TH1 PF06017.13 EGR30805.1 - 8.1e-15 55.0 3.9 1.5e-14 54.1 3.9 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Kinase-like PF14531.6 EGR30805.1 - 0.00082 18.8 0.7 0.013 14.8 0.0 2.5 3 0 0 3 3 3 1 Kinase-like Haspin_kinase PF12330.8 EGR30805.1 - 0.022 13.7 2.2 0.04 12.9 2.2 1.5 1 1 0 1 1 1 0 Haspin like kinase domain CBP_BcsR PF10945.8 EGR30805.1 - 0.052 13.0 3.6 0.076 12.5 0.1 3.0 4 0 0 4 4 4 0 Cellulose biosynthesis protein BcsR Sec3-PIP2_bind PF15277.6 EGR30805.1 - 0.057 13.5 0.3 0.2 11.8 0.1 2.1 2 0 0 2 2 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH APH PF01636.23 EGR30805.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_L1 PF00687.21 EGR30806.1 - 5.9e-29 101.3 1.6 7.4e-29 100.9 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Avl9 PF09794.9 EGR30807.1 - 2.3e-78 263.5 19.0 7e-53 179.7 7.7 2.1 1 1 1 2 2 2 2 Transport protein Avl9 SPA PF08616.10 EGR30807.1 - 1.4e-09 37.9 2.0 8.4e-08 32.2 2.0 2.6 1 1 0 1 1 1 1 Stabilization of polarity axis Afi1 PF07792.12 EGR30807.1 - 9.2e-06 26.2 0.7 9.2e-06 26.2 0.7 2.5 2 1 1 3 3 3 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF2347 PF09804.9 EGR30807.1 - 1.3e-05 25.0 9.2 8.7e-05 22.2 4.7 2.8 1 1 1 2 2 2 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 EGR30807.1 - 6.4e-05 23.0 3.8 0.00032 20.7 0.3 2.7 3 0 0 3 3 3 1 DENN (AEX-3) domain MORN PF02493.20 EGR30808.1 - 1.3e-25 87.7 38.3 1.8e-05 24.4 2.0 9.6 10 0 0 10 10 10 7 MORN repeat Pkinase PF00069.25 EGR30809.1 - 6.3e-73 245.4 1.1 8e-73 245.0 1.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30809.1 - 8.9e-38 130.0 0.3 2.1e-37 128.8 0.3 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR30809.1 - 4.4e-07 29.2 0.9 9.3e-07 28.1 0.9 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGR30809.1 - 1.3e-06 27.9 1.1 0.0038 16.6 0.3 2.5 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 EGR30809.1 - 0.1 11.9 0.1 0.21 10.9 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M8 PF01457.16 EGR30810.1 - 2.3e-42 145.4 8.6 1.4e-34 119.7 0.1 2.2 1 1 1 2 2 2 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR30810.1 - 1.2e-07 31.6 8.7 1.2e-07 31.6 8.7 2.6 3 0 0 3 3 3 1 Tenascin EGF domain EGF_2 PF07974.13 EGR30810.1 - 0.00042 20.6 10.0 0.00042 20.6 10.0 3.0 3 0 0 3 3 3 1 EGF-like domain AAA PF00004.29 EGR30811.1 - 2.6e-41 141.2 0.0 5.2e-41 140.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGR30811.1 - 3.2e-09 36.4 0.1 6.9e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGR30811.1 - 3.4e-05 24.3 0.1 0.0036 17.7 0.0 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EGR30811.1 - 4.2e-05 23.6 0.1 0.00015 21.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGR30811.1 - 5.1e-05 23.6 0.1 0.009 16.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.14 EGR30811.1 - 7.1e-05 23.0 0.0 0.00022 21.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EGR30811.1 - 0.0019 17.4 0.0 0.0033 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 EGR30811.1 - 0.002 17.9 0.0 0.012 15.4 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EGR30811.1 - 0.0043 17.3 0.0 0.0069 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGR30811.1 - 0.0064 17.0 0.0 0.018 15.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGR30811.1 - 0.01 16.0 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGR30811.1 - 0.024 14.2 0.0 0.047 13.2 0.0 1.5 1 1 0 1 1 1 0 P-loop containing dynein motor region RNA_helicase PF00910.22 EGR30811.1 - 0.037 14.4 0.0 0.093 13.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 EGR30811.1 - 0.041 13.6 0.1 0.1 12.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGR30811.1 - 0.059 12.8 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EGR30811.1 - 0.062 13.6 0.2 0.29 11.4 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGR30811.1 - 0.067 13.0 0.4 0.16 11.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EGR30811.1 - 0.083 12.8 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.13 EGR30811.1 - 0.099 11.8 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain IstB_IS21 PF01695.17 EGR30811.1 - 0.15 11.8 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein TMEM51 PF15345.6 EGR30812.1 - 0.3 10.9 12.9 0.33 10.7 12.9 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 MPM1 PF17234.2 EGR30812.1 - 0.38 11.0 15.0 0.62 10.3 15.0 1.3 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 TFIIA PF03153.13 EGR30812.1 - 0.63 10.0 32.2 0.73 9.8 32.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PNISR PF15996.5 EGR30812.1 - 1.2 9.4 19.4 1.5 9.0 19.4 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR RskA PF10099.9 EGR30812.1 - 1.4 9.2 4.8 1.7 8.9 4.8 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Dynactin_p62 PF05502.13 EGR30812.1 - 1.8 7.3 13.7 2 7.1 13.7 1.0 1 0 0 1 1 1 0 Dynactin p62 family Ndc1_Nup PF09531.10 EGR30812.1 - 6.2 5.4 14.0 7.2 5.2 14.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4647 PF15504.6 EGR30812.1 - 6.9 5.7 18.0 7.4 5.5 18.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Vac14_Fab1_bd PF12755.7 EGR30813.1 - 2e-06 28.3 11.8 0.0015 19.1 0.5 5.6 5 1 0 5 5 5 2 Vacuolar 14 Fab1-binding region Importin_rep_4 PF18808.1 EGR30813.1 - 0.00023 21.4 0.1 0.0016 18.6 0.0 2.7 2 0 0 2 2 2 1 Importin repeat RIX1 PF08167.12 EGR30813.1 - 0.56 9.9 11.1 0.42 10.3 0.6 4.7 4 1 1 5 5 5 0 rRNA processing/ribosome biogenesis DUF1981 PF09324.10 EGR30813.1 - 4.7 7.1 20.7 1.8 8.5 0.2 5.8 5 2 2 7 7 7 0 Domain of unknown function (DUF1981) Pyr_redox_2 PF07992.14 EGR30814.1 - 3.7e-50 170.8 0.0 5e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGR30814.1 - 1.3e-17 64.1 3.1 1.4e-11 44.8 0.1 3.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGR30814.1 - 2.5e-11 43.4 8.8 1.5e-06 27.7 0.6 3.0 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGR30814.1 - 1.2e-08 34.1 0.4 0.026 13.2 0.1 3.7 3 1 1 4 4 4 3 HI0933-like protein Rieske PF00355.26 EGR30814.1 - 2.1e-08 34.0 0.0 5.8e-08 32.6 0.0 1.8 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Reductase_C PF14759.6 EGR30814.1 - 8.5e-08 32.7 0.0 2.2e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Reductase C-terminal DAO PF01266.24 EGR30814.1 - 6.4e-07 29.3 0.3 0.059 12.9 0.0 3.1 3 0 0 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 EGR30814.1 - 7.9e-06 25.2 1.7 0.08 12.0 0.1 3.2 2 1 2 4 4 4 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EGR30814.1 - 9.7e-06 24.9 0.2 0.00017 20.8 0.0 2.6 2 1 1 3 3 3 1 FAD binding domain Trp_halogenase PF04820.14 EGR30814.1 - 7.6e-05 21.7 0.1 0.83 8.4 0.0 3.1 2 1 0 3 3 3 2 Tryptophan halogenase NAD_binding_7 PF13241.6 EGR30814.1 - 0.0002 21.8 0.0 0.47 10.9 0.0 2.5 2 0 0 2 2 2 2 Putative NAD(P)-binding NAD_binding_8 PF13450.6 EGR30814.1 - 0.00037 20.7 0.1 0.015 15.6 0.1 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 EGR30814.1 - 0.00042 20.3 0.0 0.35 10.8 0.0 3.4 3 1 1 4 4 4 1 FAD-NAD(P)-binding TrkA_N PF02254.18 EGR30814.1 - 0.00049 20.3 0.0 1.2 9.4 0.0 2.5 2 0 0 2 2 2 2 TrkA-N domain FAD_binding_3 PF01494.19 EGR30814.1 - 0.00079 18.8 0.0 0.0017 17.7 0.0 1.6 2 0 0 2 2 2 1 FAD binding domain AlaDh_PNT_C PF01262.21 EGR30814.1 - 0.001 18.4 0.0 0.066 12.5 0.0 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 EGR30814.1 - 0.0018 17.6 0.0 0.0057 15.9 0.0 1.7 2 0 0 2 2 2 1 Thi4 family Rieske_2 PF13806.6 EGR30814.1 - 0.003 17.5 0.1 0.01 15.8 0.0 1.9 2 0 0 2 2 1 1 Rieske-like [2Fe-2S] domain Lycopene_cycl PF05834.12 EGR30814.1 - 0.0043 16.2 0.0 0.78 8.7 0.0 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_oxidored PF12831.7 EGR30814.1 - 0.096 12.0 0.1 13 4.9 0.0 2.3 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF2122 PF09895.9 EGR30814.1 - 0.73 10.3 3.5 1.5 9.3 1.0 2.6 1 1 1 2 2 2 0 RecB-family nuclease (DUF2122) Sulf_transp PF04143.14 EGR30816.1 - 2.1e-11 44.0 13.0 2.1e-07 30.8 2.6 2.4 1 1 0 2 2 2 2 Sulphur transport Rab5ip PF07019.12 EGR30816.1 - 0.028 15.0 0.3 0.028 15.0 0.3 3.2 3 0 0 3 3 3 0 Rab5-interacting protein (Rab5ip) Peptidase_M41 PF01434.18 EGR30817.1 - 1.7e-50 171.5 0.0 1.7e-50 171.5 0.0 4.1 3 0 0 3 3 3 1 Peptidase family M41 AAA PF00004.29 EGR30817.1 - 9.5e-44 149.0 0.0 5e-43 146.7 0.0 2.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGR30817.1 - 5.2e-13 48.6 0.0 1.4e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGR30817.1 - 0.00033 20.4 0.0 0.0011 18.7 0.0 2.0 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGR30817.1 - 0.0043 17.0 0.0 0.018 15.0 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGR30817.1 - 0.0075 16.7 0.1 0.083 13.3 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 EGR30817.1 - 0.035 13.8 0.0 0.19 11.4 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGR30817.1 - 0.085 12.2 0.1 0.31 10.4 0.1 1.9 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGR30817.1 - 0.11 12.7 0.0 0.72 10.0 0.0 2.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGR30817.1 - 0.67 10.2 6.6 0.56 10.5 0.1 3.7 3 0 0 3 3 3 0 AAA domain vATP-synt_E PF01991.18 EGR30819.1 - 2.4e-38 131.6 11.7 3e-38 131.2 11.7 1.1 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit DUF4957 PF16318.5 EGR30819.1 - 0.48 10.3 8.7 0.42 10.6 5.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4957) GTP_EFTU PF00009.27 EGR30821.1 - 7.4e-34 117.0 0.9 7.4e-34 117.0 0.9 3.1 2 2 0 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EGR30821.1 - 1.9e-18 66.5 6.8 1.9e-18 66.5 6.8 2.5 2 0 0 2 2 2 1 Translation-initiation factor 2 MMR_HSR1 PF01926.23 EGR30821.1 - 3.2e-11 43.3 0.0 3.2e-11 43.3 0.0 2.4 2 1 1 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EGR30821.1 - 3.7e-07 30.5 3.0 0.0045 17.4 0.2 3.7 3 1 1 4 4 4 2 Elongation factor Tu domain 2 FeoB_N PF02421.18 EGR30821.1 - 7e-06 25.6 0.2 7e-06 25.6 0.2 2.7 2 1 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.21 EGR30821.1 - 1.3e-05 24.7 3.7 0.00021 20.8 0.0 3.0 2 1 1 3 3 3 1 ADP-ribosylation factor family Ras PF00071.22 EGR30821.1 - 0.00066 19.3 0.2 0.0031 17.1 0.0 2.3 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EGR30821.1 - 0.0019 18.4 0.0 0.0075 16.5 0.0 2.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EGR30821.1 - 0.02 14.9 8.3 0.032 14.3 0.1 3.7 2 2 1 3 3 2 0 Dynamin family GTP_EFTU_D4 PF14578.6 EGR30821.1 - 0.025 14.5 7.3 0.12 12.3 0.6 3.2 3 0 0 3 3 3 0 Elongation factor Tu domain 4 YdaS_antitoxin PF15943.5 EGR30821.1 - 0.027 14.4 0.0 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF2577 PF10844.8 EGR30821.1 - 0.11 12.7 0.1 0.11 12.7 0.1 3.1 2 1 0 2 2 1 0 Protein of unknown function (DUF2577) Pkinase PF00069.25 EGR30822.1 - 3.4e-78 262.7 0.5 4.1e-78 262.4 0.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30822.1 - 1.1e-40 139.6 0.0 1.3e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR30822.1 - 4e-05 22.7 1.2 6.1e-05 22.1 1.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGR30822.1 - 0.00086 18.7 1.2 0.053 12.8 0.4 2.2 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EGR30822.1 - 0.0018 17.2 0.0 0.0027 16.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR30822.1 - 0.05 13.0 0.1 0.085 12.2 0.1 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Anoctamin PF04547.12 EGR30823.1 - 2.9e-07 29.7 0.2 2.9e-07 29.7 0.2 1.2 1 0 0 1 1 1 1 Calcium-activated chloride channel Imm9 PF15587.6 EGR30823.1 - 0.057 13.1 1.8 0.094 12.4 1.2 1.6 1 1 1 2 2 2 0 Immunity protein 9 Ion_trans PF00520.31 EGR30824.1 - 9.7e-28 97.0 1.1 1e-27 96.9 1.1 1.0 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EGR30824.1 - 0.0013 17.5 4.9 0.077 11.7 2.7 2.0 1 1 1 2 2 2 2 Polycystin cation channel Ion_trans PF00520.31 EGR30825.1 - 5.2e-104 346.8 71.9 1.1e-46 159.1 32.3 3.3 3 0 0 3 3 3 3 Ion transport protein PKD_channel PF08016.12 EGR30825.1 - 2e-11 43.2 68.6 1.6e-06 27.1 18.4 6.2 3 2 2 6 6 6 6 Polycystin cation channel PAN_1 PF00024.26 EGR30825.1 - 0.0051 16.7 1.0 0.012 15.6 1.0 1.6 1 0 0 1 1 1 1 PAN domain DUF5423 PF17461.2 EGR30825.1 - 0.18 10.6 0.6 0.41 9.4 0.6 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5423) DNA_pol_B PF00136.21 EGR30826.1 - 5e-105 351.9 23.1 5e-105 351.9 23.1 2.0 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EGR30826.1 - 1.2e-15 57.6 16.6 1.2e-15 57.6 16.6 3.5 3 2 1 4 4 4 1 DNA polymerase family B, exonuclease domain DnaJ PF00226.31 EGR30829.1 - 7e-27 93.3 4.5 7e-27 93.3 4.5 2.3 2 0 0 2 2 2 1 DnaJ domain Fibrinogen_aC PF12160.8 EGR30829.1 - 0.19 11.6 0.5 0.37 10.7 0.5 1.4 1 0 0 1 1 1 0 Fibrinogen alpha C domain EVI2A PF05399.11 EGR30829.1 - 2 7.9 6.1 0.21 11.1 0.1 2.1 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) ANAPC4_WD40 PF12894.7 EGR30830.1 - 3.4e-08 33.7 0.1 0.035 14.4 0.0 5.2 2 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGR30830.1 - 1.4e-07 32.1 3.1 0.18 12.7 0.0 5.4 5 1 1 6 6 6 3 WD domain, G-beta repeat Vps16_N PF04841.13 EGR30830.1 - 3.5e-05 22.7 1.1 0.00011 21.2 0.1 1.9 2 0 0 2 2 2 1 Vps16, N-terminal region C2 PF00168.30 EGR30831.1 - 2.7e-07 30.8 0.3 9.9e-06 25.8 0.0 2.7 2 1 0 2 2 2 1 C2 domain CP_ATPgrasp_2 PF14403.6 EGR30831.1 - 0.07 12.0 0.2 0.12 11.3 0.2 1.3 1 0 0 1 1 1 0 Circularly permuted ATP-grasp type 2 FlgT_N PF16548.5 EGR30831.1 - 0.63 10.7 5.8 0.17 12.5 0.6 2.7 2 1 1 3 3 3 0 Flagellar assembly protein T, N-terminal domain HIGH_NTase1 PF05636.11 EGR30832.1 - 0.017 14.3 8.3 0.021 14.1 8.3 1.2 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase GBR_NSP5 PF17580.2 EGR30832.1 - 6.3 6.6 15.6 0.76 9.6 10.7 1.9 1 1 1 2 2 2 0 Group B Rotavirus Non-structural protein 5 K_trans PF02705.16 EGR30832.1 - 10 4.5 5.9 12 4.2 5.9 1.1 1 0 0 1 1 1 0 K+ potassium transporter SNF2_N PF00176.23 EGR30833.1 - 1.9e-44 151.8 4.3 4.9e-44 150.5 4.3 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGR30833.1 - 1.4e-19 70.4 0.8 1.2e-18 67.5 0.0 2.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGR30833.1 - 0.00011 22.2 0.1 0.00011 22.2 0.1 4.6 4 2 0 4 4 4 1 Type III restriction enzyme, res subunit SLIDE PF09111.10 EGR30833.1 - 0.00042 20.3 2.7 0.00042 20.3 2.7 4.7 5 2 1 6 6 6 1 SLIDE AAA_14 PF13173.6 EGR30833.1 - 0.00089 19.3 0.5 0.011 15.8 0.5 3.0 1 0 0 1 1 1 1 AAA domain Myb_DNA-binding PF00249.31 EGR30833.1 - 0.0016 18.6 0.1 0.0098 16.1 0.1 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain AAA_22 PF13401.6 EGR30833.1 - 0.0032 17.7 0.3 0.027 14.8 0.0 2.6 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 EGR30833.1 - 0.027 14.3 0.1 0.11 12.2 0.1 2.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase RRM_1 PF00076.22 EGR30834.1 - 3e-15 55.8 0.4 7.1e-15 54.6 0.4 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FHA PF00498.26 EGR30834.1 - 3.7e-15 56.0 0.0 1.2e-14 54.4 0.0 1.9 1 0 0 1 1 1 1 FHA domain DUF1768 PF08719.11 EGR30834.1 - 2.9e-07 30.9 4.5 3.6e-07 30.5 0.1 3.1 3 1 0 3 3 3 1 Domain of unknown function (DUF1768) Yop-YscD_cpl PF16697.5 EGR30834.1 - 9.6e-07 29.0 0.0 2.7e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain RRM_3 PF08777.11 EGR30834.1 - 0.0062 16.6 3.1 0.0084 16.1 1.0 2.3 2 0 0 2 2 2 1 RNA binding motif RRM_7 PF16367.5 EGR30834.1 - 0.067 13.3 0.1 0.26 11.4 0.1 2.1 1 1 0 1 1 1 0 RNA recognition motif UQ_con PF00179.26 EGR30835.1 - 4.9e-55 185.0 0.1 5.5e-55 184.9 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGR30835.1 - 4.5e-05 23.2 0.0 5.7e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGR30835.1 - 0.0039 17.5 0.0 0.0051 17.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 EGR30835.1 - 0.028 14.3 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain Carboxyl_trans PF01039.22 EGR30836.1 - 5e-143 477.3 0.0 6.4e-143 477.0 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EGR30836.1 - 0.0098 15.4 0.0 0.41 10.1 0.0 2.1 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) DUF3865 PF12981.7 EGR30837.1 - 0.0076 16.2 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 Domain of Unknown Function with PDB structure (DUF3865) DUF4806 PF16064.5 EGR30837.1 - 4.7 7.6 16.2 5.6 7.3 0.5 4.3 3 1 1 4 4 4 0 Domain of unknown function (DUF4806) CX9C PF16860.5 EGR30838.1 - 0.0026 17.7 2.9 0.0037 17.2 2.9 1.2 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, E1-E2_ATPase PF00122.20 EGR30839.1 - 1.2e-42 145.5 1.0 2.5e-42 144.4 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGR30839.1 - 6.1e-36 123.8 0.1 6.1e-36 123.8 0.1 2.6 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGR30839.1 - 3.3e-18 66.8 0.0 1.9e-10 41.4 0.0 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGR30839.1 - 1.5e-13 50.2 0.1 6.7e-13 48.1 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGR30839.1 - 2e-13 50.2 0.0 4.8e-13 49.0 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Phage_holin_3_6 PF07332.11 EGR30839.1 - 0.52 10.4 4.9 5.4 7.1 1.5 2.5 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Hydrolase_3 PF08282.12 EGR30839.1 - 3.4 7.3 11.8 2.5 7.7 0.4 3.8 4 0 0 4 4 4 0 haloacid dehalogenase-like hydrolase PAS_9 PF13426.7 EGR30840.1 - 0.0039 17.4 0.1 0.0039 17.4 0.1 4.7 5 1 0 5 5 5 2 PAS domain Pkinase_Tyr PF07714.17 EGR30843.1 - 9.1e-18 64.5 4.1 1.5e-17 63.7 4.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGR30843.1 - 1.5e-16 60.6 6.4 3.6e-16 59.3 6.4 1.6 1 0 0 1 1 1 1 Protein kinase domain RNA_pol_Rpb2_6 PF00562.28 EGR30844.1 - 1.6e-38 132.9 0.3 2.6e-38 132.1 0.3 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGR30844.1 - 1.2e-29 103.4 0.4 2e-29 102.6 0.4 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EGR30844.1 - 1.1e-28 99.1 0.0 3.6e-28 97.5 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EGR30844.1 - 5.6e-17 62.0 0.3 1e-16 61.1 0.3 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 EGR30844.1 - 2.7e-13 49.7 0.1 8.8e-13 48.1 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_4 PF04566.13 EGR30844.1 - 0.01 16.1 0.0 0.043 14.1 0.0 2.2 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 DUF1414 PF07208.11 EGR30844.1 - 0.09 12.8 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1414) RNA_pol_Rpb2_6 PF00562.28 EGR30845.1 - 5e-35 121.3 0.4 6.4e-35 121.0 0.4 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 EGR30845.1 - 1.4e-17 63.9 0.7 3.6e-17 62.5 0.7 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 7 Pkinase PF00069.25 EGR30847.1 - 2.5e-59 200.8 2.2 2.9e-59 200.6 2.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30847.1 - 9.1e-29 100.5 0.2 1.2e-28 100.2 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR30847.1 - 0.0025 17.2 1.2 0.073 12.4 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR30847.1 - 0.0061 15.4 0.0 0.021 13.6 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase DUF3139 PF11337.8 EGR30847.1 - 0.0093 16.6 4.5 0.65 10.7 0.4 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF3139) Haspin_kinase PF12330.8 EGR30847.1 - 0.017 14.1 3.6 0.034 13.1 3.6 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 EGR30847.1 - 0.046 13.1 0.0 0.081 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Furin-like_2 PF15913.5 EGR30848.1 - 5.1e-11 42.7 146.5 1.3e-06 28.5 16.1 9.5 2 1 7 9 9 9 6 Furin-like repeat, cysteine-rich VSP PF03302.13 EGR30848.1 - 2.4e-05 23.4 67.6 7.6e-05 21.7 36.1 4.7 1 1 4 5 5 5 4 Giardia variant-specific surface protein UQ_con PF00179.26 EGR30850.1 - 8.8e-46 155.0 0.5 1e-45 154.8 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGR30850.1 - 0.025 14.3 0.1 0.059 13.1 0.1 1.8 1 1 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.22 EGR30850.1 - 0.033 14.5 0.2 0.064 13.5 0.1 1.7 1 1 1 2 2 2 0 RWD domain Choline_kinase PF01633.20 EGR30851.1 - 2.4e-06 27.3 0.0 3.8e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Mycobact_memb PF05423.13 EGR30851.1 - 0.19 11.7 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Mycobacterium membrane protein Pkinase PF00069.25 EGR30852.1 - 2.5e-63 213.9 2.3 5e-63 212.9 2.3 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30852.1 - 4e-39 134.4 0.4 6.5e-39 133.8 0.4 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR30852.1 - 3.8e-08 33.0 0.7 1e-07 31.6 0.7 1.7 1 1 0 1 1 1 1 Kinase-like MMR_HSR1 PF01926.23 EGR30853.1 - 1.4e-16 60.6 3.0 1.6e-14 53.9 0.0 2.9 2 1 1 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EGR30853.1 - 4.6e-06 26.2 0.1 4.6e-06 26.2 0.1 2.9 4 0 0 4 4 4 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGR30853.1 - 0.039 14.0 0.5 0.039 14.0 0.5 4.6 2 2 0 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 EGR30853.1 - 0.045 13.7 0.2 0.045 13.7 0.2 3.0 3 0 0 3 3 3 0 RsgA GTPase HetR_C PF18460.1 EGR30853.1 - 0.077 12.9 0.7 0.25 11.3 0.1 2.2 2 0 0 2 2 2 0 Heterocyst differentiation regulator C-terminal Hood domain AAA_16 PF13191.6 EGR30853.1 - 0.12 12.8 0.0 0.38 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EGR30853.1 - 0.22 12.1 0.0 0.22 12.1 0.0 3.4 2 1 0 2 2 2 0 AAA domain MeaB PF03308.16 EGR30853.1 - 0.46 9.4 0.0 0.46 9.4 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB CENP-O PF09496.10 EGR30853.1 - 2.1 8.3 12.5 4.5 7.2 12.5 1.6 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component PA26 PF04636.13 EGR30853.1 - 4.1 6.2 18.5 7.1 5.4 18.5 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SHIPPO-rpt PF07004.12 EGR30854.1 - 4.6e-12 46.3 17.7 0.012 16.5 0.3 6.1 5 0 0 5 5 5 5 Sperm-tail PG-rich repeat ECR1_N PF14382.6 EGR30854.1 - 0.1 12.4 0.4 38 4.2 0.0 3.4 4 0 0 4 4 4 0 Exosome complex exonuclease RRP4 N-terminal region DUF4378 PF14309.6 EGR30855.1 - 1.3e-06 28.9 5.3 1.3e-06 28.9 5.3 3.3 3 2 0 3 3 3 1 Domain of unknown function (DUF4378) IQ PF00612.27 EGR30855.1 - 0.009 15.7 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Mad3_BUB1_II PF08171.11 EGR30856.1 - 0.0025 17.9 3.2 0.037 14.2 1.0 2.5 1 1 1 2 2 2 1 Mad3/BUB1 homology region 2 DUF1350 PF07082.11 EGR30856.1 - 0.031 13.6 0.4 0.034 13.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1350) Glyco_hydro_108 PF05838.12 EGR30856.1 - 0.047 14.2 0.3 0.13 12.7 0.2 1.8 2 0 0 2 2 2 0 Glycosyl hydrolase 108 Sigma70_r4_2 PF08281.12 EGR30856.1 - 0.087 12.5 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-70, region 4 RNase_J_C PF17770.1 EGR30856.1 - 2.3 9.3 5.7 1.5 9.9 0.1 2.5 2 1 0 2 2 2 0 Ribonuclease J C-terminal domain PI-PLC-X PF00388.19 EGR30857.1 - 0.00016 21.2 0.0 0.00018 21.1 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain DNA_pol_E_B PF04042.16 EGR30858.1 - 5e-20 71.8 2.3 6.5e-20 71.4 2.3 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B PDDEXK_10 PF07788.11 EGR30858.1 - 0.086 12.8 0.0 0.96 9.4 0.0 2.4 2 0 0 2 2 2 0 PD-(D/E)XK nuclease superfamily Pkinase PF00069.25 EGR30860.1 - 8.3e-65 218.8 1.1 9.9e-65 218.5 1.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30860.1 - 8.6e-34 117.0 0.1 1.1e-33 116.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR30860.1 - 4.8e-07 29.0 6.6 8e-07 28.3 6.6 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGR30860.1 - 0.008 15.5 1.8 0.026 13.8 0.9 2.1 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR30860.1 - 0.0083 15.0 1.4 0.014 14.2 0.4 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGR30860.1 - 0.0084 16.1 0.0 0.022 14.7 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR30860.1 - 0.0085 15.5 0.2 0.012 15.0 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family CRAL_TRIO PF00650.20 EGR30861.1 - 7.3e-31 107.0 2.3 1.4e-30 106.1 2.3 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EGR30861.1 - 0.0062 16.7 0.7 0.016 15.4 0.7 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain HSP90 PF00183.18 EGR30862.1 - 7.3e-162 539.9 14.9 8.8e-162 539.6 14.9 1.0 1 0 0 1 1 1 1 Hsp90 protein Ribosomal_S20p PF01649.18 EGR30862.1 - 0.16 12.6 4.2 0.11 13.2 0.9 2.3 2 0 0 2 2 2 0 Ribosomal protein S20 HSP90 PF00183.18 EGR30863.1 - 1.1e-14 54.2 15.5 1.6e-14 53.7 15.5 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EGR30863.1 - 2.3e-14 53.8 0.0 3.5e-14 53.2 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGR30863.1 - 6.7e-11 42.2 0.1 6.7e-11 42.2 0.1 1.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CDC45 PF02724.14 EGR30863.1 - 0.77 8.0 7.9 1.1 7.5 7.9 1.2 1 0 0 1 1 1 0 CDC45-like protein EIIBC-GUT_N PF03612.14 EGR30863.1 - 2 8.1 5.3 4.7 6.9 4.7 1.9 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus MH1 PF03165.16 EGR30864.1 - 0.037 14.2 0.5 0.061 13.5 0.1 1.6 2 1 0 2 2 2 0 MH1 domain Snf7 PF03357.21 EGR30865.1 - 0.00021 21.0 35.6 0.0004 20.0 35.6 1.5 1 1 0 1 1 1 1 Snf7 DUF3987 PF13148.6 EGR30865.1 - 1 8.3 7.3 1.4 7.8 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DnaJ_C PF01556.18 EGR30866.1 - 3.4e-33 114.8 0.5 3.4e-33 114.8 0.5 1.7 2 0 0 2 2 2 1 DnaJ C terminal domain DnaJ PF00226.31 EGR30866.1 - 1e-12 48.0 6.8 3.5e-11 43.1 4.4 2.7 2 1 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGR30866.1 - 4.2e-11 43.0 20.6 9.2e-11 42.0 20.6 1.6 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGR30866.1 - 0.0046 16.9 10.7 0.32 11.0 2.1 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 EGR30866.1 - 0.012 15.2 8.6 0.024 14.3 0.5 2.5 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 EGR30866.1 - 0.091 12.8 8.8 2.2 8.4 3.3 2.3 2 0 0 2 2 2 0 Double zinc ribbon HypA PF01155.19 EGR30866.1 - 0.45 10.6 9.4 3.9 7.5 2.5 2.6 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1258 PF06869.12 EGR30866.1 - 2.4 7.6 11.7 6.4 6.2 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1258) Endotoxin_C2 PF18449.1 EGR30867.1 - 0.0012 19.2 2.6 0.0024 18.2 0.3 2.5 2 0 0 2 2 2 1 Delta endotoxin Cytochrom_B562 PF07361.11 EGR30867.1 - 0.26 12.0 10.1 1.3 9.7 0.2 2.3 2 0 0 2 2 2 0 Cytochrome b562 PhoLip_ATPase_N PF16209.5 EGR30869.1 - 5.1e-16 58.1 5.7 1.2e-15 56.9 5.7 1.7 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGR30869.1 - 5.2e-12 46.5 0.3 2.5e-08 34.5 0.3 3.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGR30869.1 - 7e-12 45.3 0.5 6.6e-11 42.2 0.1 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGR30869.1 - 2e-10 40.5 0.0 7.9e-10 38.5 0.0 2.0 2 1 0 2 2 2 1 E1-E2 ATPase PhoLip_ATPase_C PF16212.5 EGR30869.1 - 5.7e-10 39.4 0.5 5.7e-10 39.4 0.5 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal MMR_HSR1_C PF08438.10 EGR30869.1 - 0.036 14.6 2.4 2.2 8.9 0.7 3.4 1 1 1 2 2 2 0 GTPase of unknown function C-terminal DUF4392 PF14336.6 EGR30869.1 - 0.16 11.4 0.5 0.48 9.8 0.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4392) DUF4376 PF14301.6 EGR30869.1 - 0.22 11.9 1.8 0.88 10.0 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) Asp PF00026.23 EGR30870.1 - 1.1e-75 255.0 6.1 2.3e-74 250.7 6.1 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGR30870.1 - 1.1e-09 38.8 6.2 2e-06 28.1 0.1 2.8 2 1 1 3 3 3 2 Xylanase inhibitor N-terminal DUF3704 PF12488.8 EGR30870.1 - 0.17 11.6 1.8 9.3 6.0 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3704) Crystall PF00030.19 EGR30872.1 - 1.4e-08 34.8 0.0 3.8e-08 33.4 0.0 1.8 1 0 0 1 1 1 1 Beta/Gamma crystallin Inhibitor_I36 PF03995.13 EGR30872.1 - 0.0021 18.0 0.1 0.0072 16.2 0.1 2.0 1 0 0 1 1 1 1 Peptidase inhibitor family I36 DEAD PF00270.29 EGR30873.1 - 6.1e-51 172.7 1.4 2.8e-50 170.5 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR30873.1 - 3.8e-35 120.6 4.7 2.4e-34 118.0 0.3 3.5 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGR30873.1 - 9.3e-09 35.5 0.0 9.3e-09 35.5 0.0 2.6 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EGR30873.1 - 0.0015 17.3 0.1 0.003 16.3 0.1 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_22 PF13401.6 EGR30873.1 - 0.0051 17.1 0.3 0.025 14.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain Aminotran_4 PF01063.19 EGR30874.1 - 7e-24 84.9 0.0 9.6e-24 84.5 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Occludin_ELL PF07303.13 EGR30875.1 - 0.038 14.7 8.0 0.083 13.6 8.0 1.5 1 0 0 1 1 1 0 Occludin homology domain Solute_trans_a PF03619.16 EGR30876.1 - 4.2e-77 259.2 35.5 5.1e-77 259.0 35.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF4293 PF14126.6 EGR30876.1 - 0.0065 16.7 3.8 0.0065 16.7 3.8 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4293) Erf4 PF10256.9 EGR30876.1 - 0.025 14.7 0.4 2.5 8.2 0.2 2.7 2 0 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family DUF4401 PF14351.6 EGR30876.1 - 8.7 5.6 15.1 8.8 5.5 3.6 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4401) MitMem_reg PF13012.6 EGR30877.1 - 1.1e-08 35.5 3.1 1.2e-08 35.4 3.1 1.4 1 1 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EGR30877.1 - 0.00028 20.9 0.4 0.00071 19.5 0.1 1.8 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4449 PF14613.6 EGR30877.1 - 0.013 15.6 2.6 2 8.5 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) Dynamin_N PF00350.23 EGR30879.1 - 0.011 15.8 18.0 0.021 14.9 17.9 1.6 1 1 0 1 1 1 0 Dynamin family Med8 PF10232.9 EGR30879.1 - 0.17 11.4 11.6 0.29 10.7 11.6 1.4 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 LRR_6 PF13516.6 EGR30879.1 - 0.26 11.4 11.4 0.86 9.8 0.5 3.5 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 EGR30879.1 - 0.61 10.9 3.7 1.5e+02 3.6 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich Repeat Presenilin PF01080.17 EGR30879.1 - 0.9 8.2 7.6 1.1 8.0 7.6 1.1 1 0 0 1 1 1 0 Presenilin PDCD7 PF16021.5 EGR30879.1 - 3 6.9 26.1 1.1 8.3 22.5 1.9 2 0 0 2 2 2 0 Programmed cell death protein 7 DUF3332 PF11810.8 EGR30879.1 - 3.7 7.2 7.1 7.4 6.2 7.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3332) Stig1 PF04885.13 EGR30879.1 - 5.9 7.4 8.1 14 6.2 8.1 1.6 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 Membralin PF09746.9 EGR30879.1 - 6.9 5.6 10.8 0.88 8.5 7.0 1.4 2 0 0 2 2 2 0 Tumour-associated protein TERB2 PF15101.6 EGR30879.1 - 8.7 6.3 9.4 13 5.7 9.4 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Guanylate_cyc PF00211.20 EGR30880.1 - 2.3e-64 216.4 6.5 2.3e-36 125.1 0.4 2.0 1 1 1 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Cellulase PF00150.18 EGR30881.1 - 0.034 13.6 0.1 0.036 13.5 0.1 1.1 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) Metallophos PF00149.28 EGR30882.1 - 9.9e-19 68.6 0.4 9.9e-19 68.6 0.4 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase SapB_2 PF03489.17 EGR30882.1 - 1.6e-05 24.9 0.5 5.1e-05 23.3 0.5 2.0 1 0 0 1 1 1 1 Saposin-like type B, region 2 DUF2004 PF09406.10 EGR30882.1 - 0.1 13.0 2.7 0.62 10.4 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2004) GH97_C PF14509.6 EGR30883.1 - 0.8 10.0 3.9 1.1 9.5 3.9 1.2 1 0 0 1 1 1 0 Glycosyl-hydrolase 97 C-terminal, oligomerisation DUF4467 PF14729.6 EGR30883.1 - 7.3 7.0 20.2 0.77 10.1 9.4 2.2 1 1 1 2 2 2 0 Domain of unknown function with cystatin-like fold (DUF4467) ArfGap PF01412.18 EGR30885.1 - 1.5e-28 99.2 0.1 1.6e-28 99.1 0.1 1.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PLA1 PF02253.15 EGR30885.1 - 0.0051 16.5 0.0 0.0062 16.2 0.0 1.2 1 0 0 1 1 1 1 Phospholipase A1 zf-B_box PF00643.24 EGR30885.1 - 0.14 12.3 0.7 5.8 7.1 0.1 2.1 2 0 0 2 2 2 0 B-box zinc finger Kinesin PF00225.23 EGR30886.1 - 1.1e-62 211.9 10.4 1.1e-62 211.9 10.4 4.2 4 1 0 5 5 5 1 Kinesin motor domain Microtub_bd PF16796.5 EGR30886.1 - 1.6e-16 60.6 4.0 1.6e-16 60.6 4.0 4.2 2 1 1 3 3 3 1 Microtubule binding ANAPC4_WD40 PF12894.7 EGR30886.1 - 0.00065 19.9 0.0 0.0022 18.3 0.0 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain T2SSE PF00437.20 EGR30886.1 - 0.0044 16.1 0.0 0.016 14.3 0.0 1.9 1 0 0 1 1 1 1 Type II/IV secretion system protein TPR_2 PF07719.17 EGR30886.1 - 0.2 11.8 1.4 0.73 10.1 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Actin PF00022.19 EGR30887.1 - 1.6e-121 405.8 0.0 1.8e-121 405.6 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGR30887.1 - 9.2e-06 24.7 0.0 0.054 12.3 0.0 2.7 2 1 0 2 2 2 2 MreB/Mbl protein HECT PF00632.25 EGR30889.1 - 6.5e-74 249.2 8.2 7.6e-74 249.0 8.2 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PI3_PI4_kinase PF00454.27 EGR30890.1 - 4e-69 233.2 0.1 4e-69 233.2 0.1 3.7 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EGR30890.1 - 4.1e-52 177.5 17.9 4.1e-52 177.5 17.9 6.3 7 0 0 7 7 7 1 FAT domain FRB_dom PF08771.11 EGR30890.1 - 1.3e-30 105.7 2.9 1.3e-30 105.7 2.9 6.4 6 0 0 6 6 6 1 FKBP12-rapamycin binding domain DUF3385 PF11865.8 EGR30890.1 - 1.2e-27 96.8 35.6 1.3e-26 93.4 4.3 7.8 4 2 0 5 5 5 3 Domain of unknown function (DUF3385) FATC PF02260.20 EGR30890.1 - 7.2e-14 51.3 0.7 1.8e-13 50.0 0.7 1.8 1 0 0 1 1 1 1 FATC domain HEAT PF02985.22 EGR30890.1 - 1.5e-06 28.0 2.6 0.068 13.5 0.0 6.6 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 EGR30890.1 - 3.1e-05 24.3 0.0 0.11 12.9 0.0 4.2 3 0 0 3 3 3 1 HEAT repeats Cnd1 PF12717.7 EGR30890.1 - 0.00069 19.7 3.0 0.00069 19.7 3.0 9.3 6 2 1 8 8 8 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGR30890.1 - 0.003 18.1 17.7 0.18 12.5 0.2 7.4 6 2 1 7 7 7 2 Vacuolar 14 Fab1-binding region CUT PF02376.15 EGR30890.1 - 0.011 15.8 2.0 0.55 10.4 0.0 4.1 2 1 1 3 3 3 0 CUT domain Asp PF00026.23 EGR30891.1 - 1.3e-20 74.1 2.0 2e-10 40.6 0.1 2.0 1 1 1 2 2 2 2 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGR30891.1 - 0.00021 21.6 2.8 0.0025 18.1 0.7 2.2 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Pkinase PF00069.25 EGR30892.1 - 3.7e-15 56.0 0.0 4e-15 55.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30892.1 - 3.7e-05 23.2 0.0 4e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR30892.1 - 0.049 12.4 0.0 0.056 12.2 0.0 1.0 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 EGR30893.1 - 1.2e-49 169.1 0.0 1.4e-49 168.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30893.1 - 1.3e-27 96.8 0.0 1.5e-27 96.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR30893.1 - 2.2e-06 26.9 0.0 3.1e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGR30893.1 - 2.8e-05 23.6 0.0 3.3e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR30893.1 - 0.00015 21.2 0.0 0.0002 20.8 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGR30893.1 - 0.00044 19.9 0.1 0.00062 19.4 0.1 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EGR30893.1 - 0.00089 19.2 0.0 0.0012 18.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGR30893.1 - 0.00098 18.0 0.0 0.0012 17.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase TTL PF03133.15 EGR30894.1 - 2.8e-25 89.1 7.6 5.7e-20 71.6 4.1 2.5 2 1 1 3 3 3 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR30894.1 - 6.5e-06 25.6 0.3 0.00027 20.3 0.0 2.6 2 1 1 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR30894.1 - 0.00087 18.6 0.0 0.052 12.8 0.0 2.2 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RecG_N PF17190.4 EGR30894.1 - 0.0012 19.5 1.0 0.004 17.8 1.0 1.9 1 0 0 1 1 1 1 RecG N-terminal helical domain Dala_Dala_lig_C PF07478.13 EGR30894.1 - 0.0061 16.1 0.1 0.02 14.4 0.1 1.9 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus YgaB PF14182.6 EGR30894.1 - 0.044 14.2 1.6 0.39 11.1 0.1 2.3 2 0 0 2 2 2 0 YgaB-like protein Kelch_5 PF13854.6 EGR30895.1 - 2e-29 101.0 0.9 0.0021 18.0 0.0 7.0 7 0 0 7 7 7 6 Kelch motif Kelch_3 PF13415.6 EGR30895.1 - 6.8e-22 77.3 0.1 0.00033 20.9 0.0 7.8 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_4 PF13418.6 EGR30895.1 - 4e-21 74.7 5.8 2.3e-06 27.5 0.0 6.1 5 1 1 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 EGR30895.1 - 2.2e-16 59.1 1.2 0.012 15.6 0.0 6.7 7 0 0 7 7 7 3 Kelch motif Metallophos PF00149.28 EGR30895.1 - 3.3e-12 47.3 0.3 3.3e-12 47.3 0.3 2.7 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase Kelch_6 PF13964.6 EGR30895.1 - 1.6e-08 34.5 5.5 2.7 8.4 0.3 6.5 4 2 3 7 7 7 4 Kelch motif Kelch_1 PF01344.25 EGR30895.1 - 2.3e-07 30.3 5.7 3.7 7.2 0.0 6.6 6 1 1 7 7 7 2 Kelch motif RAG2 PF03089.14 EGR30895.1 - 2.9e-05 23.2 0.8 0.55 9.2 0.0 3.8 3 1 0 4 4 4 2 Recombination activating protein 2 GTP_EFTU PF00009.27 EGR30896.1 - 3.6e-42 144.1 0.1 5.1e-42 143.6 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGR30896.1 - 7.6e-22 77.7 0.1 2e-21 76.4 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain PIP5K PF01504.18 EGR30896.1 - 2.6e-15 56.4 0.4 2.6e-15 56.4 0.4 2.5 3 1 1 4 4 4 1 Phosphatidylinositol-4-phosphate 5-Kinase GTP_EFTU_D2 PF03144.25 EGR30896.1 - 1.3e-07 31.8 0.0 3.3e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGR30896.1 - 0.0001 22.4 0.0 0.00047 20.2 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EGR30896.1 - 0.0093 15.7 0.0 1.7 8.3 0.0 2.7 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EGR30896.1 - 0.047 13.6 0.0 4.3 7.2 0.0 3.1 3 0 0 3 3 3 0 RsgA GTPase DUF1199 PF06712.11 EGR30897.1 - 0.037 14.1 0.1 0.071 13.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1199) CPSF73-100_C PF11718.8 EGR30898.1 - 0.015 14.8 1.2 1.8 8.1 0.0 2.1 1 1 1 2 2 2 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Glycophorin_A PF01102.18 EGR30898.1 - 0.18 12.0 0.3 0.34 11.2 0.3 1.5 1 0 0 1 1 1 0 Glycophorin A YmgD PF16456.5 EGR30899.1 - 0.00088 19.3 0.5 0.0025 17.8 0.0 2.0 2 1 0 2 2 2 1 YmgD protein DUF4959 PF16323.5 EGR30899.1 - 0.027 14.8 0.4 13 6.2 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4959) BST2 PF16716.5 EGR30899.1 - 2.3 8.8 20.9 1.2 9.8 13.2 2.7 2 1 1 3 3 3 0 Bone marrow stromal antigen 2 Peptidase_S46 PF10459.9 EGR30899.1 - 2.7 6.5 10.2 3.3 6.2 10.2 1.1 1 0 0 1 1 1 0 Peptidase S46 ASH PF15780.5 EGR30900.1 - 1.1e-20 73.7 23.6 0.00042 20.5 0.1 13.2 13 0 0 13 13 13 6 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 EGR30900.1 - 2.7e-09 36.8 37.0 0.015 15.1 0.5 11.8 13 0 0 13 13 13 3 MSP (Major sperm protein) domain DUF1573 PF07610.11 EGR30900.1 - 2.5e-08 33.8 23.1 0.0065 16.5 0.4 8.4 9 0 0 9 9 9 3 Protein of unknown function (DUF1573) PapD-like PF14874.6 EGR30900.1 - 5.3e-07 29.7 0.1 0.00011 22.3 0.0 3.7 3 0 0 3 3 3 1 Flagellar-associated PapD-like TMEM131_like PF12371.8 EGR30900.1 - 3e-05 24.2 28.2 1.3 9.4 0.0 9.8 10 0 0 10 10 10 3 Transmembrane protein 131-like Transglut_C PF00927.22 EGR30900.1 - 0.037 14.2 6.5 0.75 10.0 0.3 5.8 5 0 0 5 5 5 0 Transglutaminase family, C-terminal ig like domain fn3_6 PF17766.1 EGR30900.1 - 1.7 8.8 8.4 27 5.0 0.0 4.9 5 0 0 5 5 5 0 Fibronectin type-III domain mRNA_cap_enzyme PF01331.19 EGR30901.1 - 2.3e-21 76.5 8.6 6.2e-13 49.0 0.2 3.6 2 1 2 4 4 4 3 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EGR30901.1 - 2.4e-09 37.8 10.1 2.4e-09 37.8 10.1 2.8 3 1 0 3 3 3 1 mRNA capping enzyme, C-terminal domain MORN PF02493.20 EGR30902.1 - 2.4e-22 77.4 43.9 8.3e-07 28.5 5.2 7.8 8 0 0 8 8 8 6 MORN repeat Tudor_2 PF18104.1 EGR30902.1 - 0.78 9.5 7.9 2 8.1 0.1 4.0 4 0 0 4 4 4 0 Jumonji domain-containing protein 2A Tudor domain GDE_C PF06202.14 EGR30903.1 - 6.5e-69 232.7 1.0 8.4e-68 229.0 1.0 2.0 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EGR30903.1 - 1.5e-13 51.0 0.3 4.8e-13 49.4 0.4 1.7 1 1 1 2 2 2 1 Central domain of human glycogen debranching enzyme AMPK1_CBM PF16561.5 EGR30903.1 - 0.026 14.7 0.0 0.077 13.2 0.0 1.7 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase hDGE_amylase PF14701.6 EGR30904.1 - 8.1e-42 143.8 0.4 8.8e-42 143.7 0.4 1.0 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain Alpha-amylase PF00128.24 EGR30904.1 - 0.027 14.0 0.1 0.03 13.9 0.1 1.1 1 0 0 1 1 1 0 Alpha amylase, catalytic domain Tsc35 PF15079.6 EGR30904.1 - 0.11 12.0 0.2 0.11 12.0 0.2 1.7 2 0 0 2 2 2 0 Testis-specific protein 35 DUF3552 PF12072.8 EGR30905.1 - 0.6 9.5 17.0 0.55 9.6 15.7 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3552) DUF573 PF04504.14 EGR30905.1 - 4.9 7.9 8.6 1.4 9.6 4.6 2.2 2 1 0 2 2 2 0 Protein of unknown function, DUF573 Peptidase_A22B PF04258.13 EGR30906.1 - 8.7e-66 222.3 23.8 8.7e-66 222.3 23.8 1.7 2 0 0 2 2 2 1 Signal peptide peptidase HU-CCDC81_euk_2 PF18289.1 EGR30907.1 - 1.2e-12 47.8 0.2 1.9e-12 47.2 0.2 1.3 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 Phage_F PF02305.17 EGR30908.1 - 0.049 12.4 0.1 0.052 12.3 0.1 1.1 1 0 0 1 1 1 0 Capsid protein (F protein) Oxysterol_BP PF01237.18 EGR30908.1 - 0.1 11.4 6.1 0.22 10.3 0.0 2.2 2 0 0 2 2 2 0 Oxysterol-binding protein DUF2052 PF09747.9 EGR30908.1 - 0.31 11.1 13.3 0.43 10.7 13.3 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CENP-B_dimeris PF09026.10 EGR30908.1 - 0.48 10.8 7.6 0.78 10.2 7.6 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF4611 PF15387.6 EGR30908.1 - 0.53 10.5 10.3 1.1 9.6 10.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Myc_N PF01056.18 EGR30908.1 - 1.7 8.5 9.8 2.2 8.1 9.8 1.2 1 0 0 1 1 1 0 Myc amino-terminal region FAM176 PF14851.6 EGR30908.1 - 2 8.1 8.3 3.1 7.4 8.3 1.4 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 EGR30908.1 - 3.5 5.8 8.4 4 5.6 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein RPA43_OB PF17875.1 EGR30908.1 - 9.3 6.9 8.3 31 5.2 8.3 1.9 1 1 0 1 1 1 0 RPA43 OB domain in RNA Pol I TPR_1 PF00515.28 EGR30909.1 - 5.1e-198 633.8 196.8 5.1e-12 45.1 2.7 31.5 31 0 0 31 31 31 31 Tetratricopeptide repeat TPR_2 PF07719.17 EGR30909.1 - 2.3e-164 520.7 123.9 9.7e-09 34.7 0.7 31.4 31 0 0 31 31 31 31 Tetratricopeptide repeat TPR_8 PF13181.6 EGR30909.1 - 4.9e-132 419.4 169.5 3.1e-08 33.2 1.9 31.2 31 0 0 31 31 31 27 Tetratricopeptide repeat TPR_11 PF13414.6 EGR30909.1 - 4.4e-107 349.5 166.3 1.9e-10 40.2 0.3 29.4 10 6 21 31 31 31 24 TPR repeat TPR_12 PF13424.6 EGR30909.1 - 1.1e-89 294.8 44.6 2.1e-06 27.9 0.2 22.0 7 7 14 22 22 22 19 Tetratricopeptide repeat TPR_17 PF13431.6 EGR30909.1 - 1.5e-84 272.4 121.2 4e-06 26.8 0.3 29.2 30 0 0 30 30 30 20 Tetratricopeptide repeat TPR_16 PF13432.6 EGR30909.1 - 1.7e-64 214.2 0.0 8.2e-08 32.8 0.0 17.3 10 5 8 20 20 20 13 Tetratricopeptide repeat TPR_7 PF13176.6 EGR30909.1 - 1.4e-57 187.6 56.8 0.028 14.5 0.0 27.7 27 2 2 29 29 29 14 Tetratricopeptide repeat TPR_19 PF14559.6 EGR30909.1 - 1.2e-52 176.2 35.4 0.00058 20.3 0.1 17.3 11 4 5 17 17 17 15 Tetratricopeptide repeat TPR_14 PF13428.6 EGR30909.1 - 2e-50 165.1 0.0 0.005 17.6 0.0 23.8 8 4 19 27 27 26 9 Tetratricopeptide repeat TPR_6 PF13174.6 EGR30909.1 - 9.4e-42 138.9 62.3 0.00017 22.0 0.0 26.3 27 2 2 29 29 27 5 Tetratricopeptide repeat TPR_10 PF13374.6 EGR30909.1 - 2.2e-39 132.3 40.8 0.05 13.5 0.2 23.6 26 1 1 27 27 24 11 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR30909.1 - 1.2e-36 124.8 113.2 1.4e-07 31.6 3.2 14.0 5 4 10 17 17 17 13 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGR30909.1 - 9.7e-36 121.8 0.0 0.0046 17.1 0.0 13.4 11 2 5 16 16 15 11 Tetratricopeptide repeat NARP1 PF12569.8 EGR30909.1 - 2.8e-12 46.3 74.4 0.0049 15.8 0.5 13.3 3 3 10 14 14 14 7 NMDA receptor-regulated protein 1 DUF3856 PF12968.7 EGR30909.1 - 1.2e-05 25.5 18.6 3.9 7.5 0.0 11.3 4 4 5 10 10 10 1 Domain of Unknown Function (DUF3856) TPR_20 PF14561.6 EGR30909.1 - 4.2e-05 23.8 6.4 31 5.0 0.1 8.4 6 3 3 10 10 10 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGR30909.1 - 0.00021 20.7 32.5 0.27 10.7 0.6 12.0 13 1 1 14 14 14 2 SHNi-TPR TPR_3 PF07720.12 EGR30909.1 - 0.0019 18.2 0.1 0.0019 18.2 0.1 16.6 20 0 0 20 20 17 4 Tetratricopeptide repeat DUF5113 PF17140.4 EGR30909.1 - 0.0056 16.5 0.3 0.0056 16.5 0.3 16.2 2 2 12 19 19 19 3 Domain of unknown function (DUF5113) BTAD PF03704.17 EGR30909.1 - 0.0082 16.6 0.1 29 5.1 0.0 5.1 5 1 1 6 6 6 0 Bacterial transcriptional activator domain PknG_TPR PF16918.5 EGR30909.1 - 0.088 11.5 0.0 15 4.2 0.0 2.8 2 0 0 2 2 2 0 Protein kinase G tetratricopeptide repeat Sel1 PF08238.12 EGR30909.1 - 0.16 12.7 33.4 7.9 7.3 0.1 11.5 13 0 0 13 13 10 0 Sel1 repeat TPR_15 PF13429.6 EGR30909.1 - 0.22 10.7 19.1 2.8 7.1 0.7 7.0 4 2 3 7 7 7 0 Tetratricopeptide repeat XS PF03468.14 EGR30909.1 - 6 7.2 18.8 0.5 10.7 1.5 6.5 5 2 2 7 7 7 0 XS domain AAA PF00004.29 EGR30910.1 - 4.1e-47 159.9 0.0 1.4e-46 158.2 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGR30910.1 - 7.4e-07 29.7 0.2 0.0027 18.1 0.0 2.8 3 1 0 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 EGR30910.1 - 1.1e-06 28.5 0.0 3.2e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGR30910.1 - 0.00016 21.7 0.1 0.0011 19.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EGR30910.1 - 0.00025 21.4 0.0 0.00053 20.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_11 PF13086.6 EGR30910.1 - 0.00032 20.6 0.6 0.00091 19.1 0.6 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGR30910.1 - 0.00034 20.8 0.0 0.00079 19.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGR30910.1 - 0.00053 19.8 0.0 0.0011 18.7 0.0 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 EGR30910.1 - 0.00057 19.5 0.3 0.34 10.4 0.0 2.5 2 1 0 3 3 3 2 AAA domain AAA_7 PF12775.7 EGR30910.1 - 0.00061 19.4 0.0 0.0021 17.6 0.0 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_22 PF13401.6 EGR30910.1 - 0.00066 20.0 1.8 0.013 15.8 0.1 2.8 2 1 1 3 3 3 1 AAA domain TIP49 PF06068.13 EGR30910.1 - 0.001 18.3 0.2 0.02 14.1 0.0 2.1 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_2 PF07724.14 EGR30910.1 - 0.0011 19.1 0.0 0.0036 17.4 0.0 1.9 2 1 0 2 2 1 1 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EGR30910.1 - 0.0023 17.3 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EGR30910.1 - 0.0027 17.8 0.1 0.0072 16.4 0.0 1.8 2 0 0 2 2 1 1 AAA domain Parvo_NS1 PF01057.17 EGR30910.1 - 0.0036 16.5 0.0 0.0062 15.7 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 EGR30910.1 - 0.018 15.1 0.0 3.8 7.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_3 PF07726.11 EGR30910.1 - 0.022 14.6 0.0 0.046 13.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EGR30910.1 - 0.027 15.0 1.0 0.12 12.9 1.0 2.1 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 EGR30910.1 - 0.027 14.4 0.1 0.92 9.4 0.0 2.3 1 1 0 2 2 2 0 NACHT domain Sigma54_activat PF00158.26 EGR30910.1 - 0.034 13.9 0.0 0.57 9.9 0.0 2.4 1 1 0 2 2 2 0 Sigma-54 interaction domain AAA_18 PF13238.6 EGR30910.1 - 0.038 14.5 0.2 0.12 12.9 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_lid_3 PF17862.1 EGR30910.1 - 0.044 13.6 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA+ lid domain AAA_24 PF13479.6 EGR30910.1 - 0.059 13.1 0.5 0.12 12.0 0.1 1.9 2 1 0 2 2 2 0 AAA domain TsaE PF02367.17 EGR30910.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EGR30910.1 - 0.07 13.0 2.3 0.53 10.2 0.0 2.6 2 1 0 2 2 2 0 Rad17 P-loop domain NB-ARC PF00931.22 EGR30910.1 - 0.091 11.9 0.6 1 8.5 0.1 2.7 2 2 0 2 2 2 0 NB-ARC domain AAA_23 PF13476.6 EGR30910.1 - 0.13 12.8 11.8 1.2 9.6 11.8 2.3 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGR30910.1 - 0.15 12.3 0.0 0.41 10.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain TMIE PF16038.5 EGR30910.1 - 0.64 9.9 3.1 13 5.7 2.4 2.5 2 0 0 2 2 2 0 TMIE protein DAO PF01266.24 EGR30911.1 - 8.4e-16 58.5 0.0 2.6e-15 56.9 0.0 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase Glycos_transf_1 PF00534.20 EGR30911.1 - 0.01 15.4 1.6 0.017 14.6 1.6 1.3 1 0 0 1 1 1 0 Glycosyl transferases group 1 CAF1C_H4-bd PF12265.8 EGR30912.1 - 1.3e-26 92.6 0.5 6.7e-26 90.4 0.3 2.3 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGR30912.1 - 7.2e-23 80.5 8.0 7.5e-06 26.6 0.0 5.5 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR30912.1 - 0.00018 21.8 1.3 1.3 9.3 0.0 4.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGR30912.1 - 0.00092 18.6 0.0 1.3 8.3 0.0 2.3 2 0 0 2 2 2 2 WD40-like domain Pkinase PF00069.25 EGR30913.1 - 5.9e-69 232.4 0.3 7e-69 232.1 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30913.1 - 1e-38 133.1 0.1 1.3e-38 132.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR30913.1 - 7.2e-07 28.8 0.3 1.6e-05 24.4 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR30913.1 - 0.0026 16.6 0.0 0.006 15.4 0.0 1.5 1 1 1 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EGR30914.1 - 1e-14 54.6 0.0 1.2e-14 54.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30914.1 - 7.9e-06 25.3 0.0 1e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Citrate_synt PF00285.21 EGR30915.1 - 5.7e-87 292.1 0.0 7.2e-87 291.8 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Choline_transpo PF04515.12 EGR30917.1 - 8e-90 301.3 36.3 8e-90 301.3 36.3 3.5 2 1 2 4 4 4 1 Plasma-membrane choline transporter Cpta_toxin PF07254.12 EGR30917.1 - 4.9 7.1 5.9 6.6 6.7 3.1 2.5 2 0 0 2 2 2 0 Membrane-bound toxin component of toxin-antitoxin system DUF3593 PF12159.8 EGR30917.1 - 8.1 6.6 16.8 0.4 10.7 4.9 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3593) Rtf2 PF04641.12 EGR30918.1 - 6.6e-07 29.0 1.1 6.6e-07 29.0 1.1 1.8 2 0 0 2 2 2 1 Rtf2 RING-finger zf-RING_UBOX PF13445.6 EGR30918.1 - 0.00012 22.0 0.1 0.00041 20.3 0.1 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGR30918.1 - 0.0015 18.8 0.2 0.0049 17.2 0.2 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGR30918.1 - 0.0018 18.2 1.2 0.0034 17.3 0.4 2.0 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGR30918.1 - 0.0034 17.2 0.4 0.0086 15.9 0.4 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EGR30918.1 - 0.025 14.4 0.3 0.085 12.7 0.3 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGR30918.1 - 0.057 13.6 3.5 0.25 11.5 0.7 3.3 3 1 1 4 4 4 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EGR30918.1 - 0.11 12.5 2.3 0.14 12.3 0.3 2.0 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 EGR30918.1 - 1 9.3 6.3 0.22 11.4 2.3 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Nop PF01798.18 EGR30919.1 - 8.9e-64 215.1 0.2 8.9e-64 215.1 0.2 1.5 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EGR30919.1 - 7.2e-18 65.7 4.0 2.7e-17 63.8 4.0 2.0 1 0 0 1 1 1 1 Prp31 C terminal domain CutA1 PF03091.15 EGR30919.1 - 0.16 11.9 1.5 1.3 8.9 0.0 2.4 2 0 0 2 2 2 0 CutA1 divalent ion tolerance protein WD40 PF00400.32 EGR30920.1 - 4.2e-12 46.4 0.0 1.7e-05 25.4 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat LisH_TPL PF17814.1 EGR30920.1 - 5e-12 45.3 0.6 1.2e-11 44.1 0.6 1.7 1 0 0 1 1 1 1 LisH-like dimerisation domain ANAPC4_WD40 PF12894.7 EGR30920.1 - 6.2e-08 32.8 0.2 0.0079 16.5 0.0 3.2 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGR30920.1 - 0.00043 19.4 0.1 0.013 14.5 0.0 2.3 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein LisH PF08513.11 EGR30920.1 - 0.028 14.4 0.0 0.078 13.0 0.0 1.8 1 0 0 1 1 1 0 LisH RNA_pol_Rpc4 PF05132.14 EGR30921.1 - 4.7e-09 36.8 0.0 5.1e-09 36.7 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase III RPC4 Sugar_tr PF00083.24 EGR30923.1 - 9.7e-17 61.0 16.7 1.2e-16 60.6 16.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGR30923.1 - 3.5e-13 49.2 6.7 3.5e-13 49.2 6.7 1.7 1 1 0 2 2 2 1 Major Facilitator Superfamily GDA1_CD39 PF01150.17 EGR30924.1 - 3.8e-63 213.6 13.0 5e-63 213.2 13.0 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ppx-GppA PF02541.16 EGR30924.1 - 0.0066 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 Ppx/GppA phosphatase family Zap1_zf2 PF18217.1 EGR30924.1 - 0.24 11.4 1.0 0.67 10.0 1.0 1.7 1 0 0 1 1 1 0 Zap1 zinc finger 2 Sad1_UNC PF07738.13 EGR30925.1 - 0.033 14.2 3.4 3 7.9 0.1 3.5 2 1 1 3 3 3 0 Sad1 / UNC-like C-terminal UCH PF00443.29 EGR30926.1 - 7.9e-30 104.2 0.6 2e-22 79.9 0.1 3.1 1 1 2 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR30926.1 - 1.1e-24 87.7 0.2 1.7e-19 70.6 0.0 3.1 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase TetR_C_27 PF17935.1 EGR30926.1 - 0.0089 16.1 0.1 2.1 8.4 0.0 2.5 2 0 0 2 2 2 2 Tetracyclin repressor-like, C-terminal domain zf-FPG_IleRS PF06827.14 EGR30926.1 - 0.3 11.0 1.6 0.57 10.1 0.1 2.2 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS ALMT PF11744.8 EGR30926.1 - 1.1 8.0 20.3 6.1 5.6 20.3 1.9 1 1 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 EGR30926.1 - 1.3 7.7 16.3 1.8 7.3 16.3 1.2 1 0 0 1 1 1 0 Presenilin LMBR1 PF04791.16 EGR30926.1 - 3.2 6.5 11.3 4.2 6.2 11.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein VPS13_C PF16909.5 EGR30928.1 - 7.4e-59 198.5 15.3 1.3e-54 184.7 1.0 3.4 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 EGR30928.1 - 1.8e-42 145.6 6.9 1.8e-42 145.6 6.9 4.9 3 1 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 EGR30928.1 - 1.5e-31 110.1 9.9 1.5e-31 110.1 9.9 5.5 6 0 0 6 6 6 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 EGR30928.1 - 9.2e-27 93.5 0.3 9.2e-27 93.5 0.3 7.7 8 0 0 8 8 8 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 EGR30928.1 - 4.7e-17 62.2 2.5 4.7e-17 62.2 2.5 8.4 8 2 2 10 10 10 3 Repeating coiled region of VPS13 ATG_C PF09333.11 EGR30928.1 - 5.2e-08 33.1 0.1 2.7e-07 30.8 0.1 2.3 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain PH PF00169.29 EGR30928.1 - 2.3e-06 28.0 0.3 2.3e-06 28.0 0.3 3.4 2 0 0 2 2 2 1 PH domain E1-E2_ATPase PF00122.20 EGR30929.1 - 7.4e-30 103.8 0.0 3.1e-29 101.8 0.0 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGR30929.1 - 5.3e-14 53.0 0.0 2.3e-05 24.8 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGR30929.1 - 1.5e-06 28.2 0.0 1.3e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) P5-ATPase PF12409.8 EGR30929.1 - 4.1e-05 23.7 1.2 4.1e-05 23.7 1.2 2.4 2 1 0 2 2 2 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 EGR30929.1 - 0.00016 21.3 0.0 0.00044 19.9 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Ras PF00071.22 EGR30930.1 - 2e-48 164.1 4.1 1.1e-24 86.9 0.9 2.6 1 1 2 3 3 3 2 Ras family Roc PF08477.13 EGR30930.1 - 2.7e-30 105.0 1.3 3.6e-21 75.6 0.0 2.5 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR30930.1 - 8.4e-09 35.1 0.7 1.9e-08 34.0 0.7 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGR30930.1 - 5.3e-07 29.2 0.4 9.6e-07 28.4 0.4 1.5 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGR30930.1 - 9.6e-07 28.8 1.4 0.021 14.8 0.6 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGR30930.1 - 0.00015 21.8 0.2 0.00054 20.0 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGR30930.1 - 0.00025 20.5 0.1 0.00054 19.4 0.1 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 EGR30930.1 - 0.0026 17.2 0.1 0.22 10.9 0.0 2.3 2 0 0 2 2 2 1 Bacterial TniB protein Phage_cap_E PF03864.15 EGR30930.1 - 0.0056 15.9 0.0 0.0087 15.3 0.0 1.4 1 1 0 1 1 1 1 Phage major capsid protein E Phage_GPO PF05929.11 EGR30930.1 - 0.019 14.6 1.0 0.024 14.3 1.0 1.1 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase AAA_22 PF13401.6 EGR30930.1 - 0.026 14.8 0.1 1 9.6 0.0 2.5 1 1 1 2 2 2 0 AAA domain AnfG_VnfG PF03139.15 EGR30930.1 - 0.034 14.2 0.9 0.082 13.0 0.7 1.7 1 1 0 1 1 1 0 Vanadium/alternative nitrogenase delta subunit CorA PF01544.18 EGR30930.1 - 0.04 13.2 0.5 0.055 12.8 0.5 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein NACHT PF05729.12 EGR30930.1 - 0.048 13.6 0.0 0.25 11.2 0.0 2.3 2 1 0 2 2 2 0 NACHT domain MMR_HSR1_Xtn PF16897.5 EGR30930.1 - 0.049 13.6 0.3 0.087 12.8 0.3 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 EGR30930.1 - 0.072 13.5 0.0 0.22 11.9 0.0 1.9 1 1 1 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 EGR30930.1 - 0.14 12.7 2.4 8 7.0 0.0 2.3 2 1 0 2 2 2 0 ABC transporter ubiquitin PF00240.23 EGR30931.1 - 2.4e-133 434.1 15.9 1.7e-32 111.0 0.3 4.1 4 0 0 4 4 4 4 Ubiquitin family Rad60-SLD PF11976.8 EGR30931.1 - 8.4e-60 198.5 18.8 2.9e-14 52.6 0.5 4.2 4 0 0 4 4 4 4 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGR30931.1 - 2.4e-21 76.0 6.5 0.0021 18.5 0.1 5.8 4 4 0 4 4 4 4 Ubiquitin-like domain TBK1_ULD PF18396.1 EGR30931.1 - 2.3e-13 49.9 2.8 0.14 12.1 0.1 4.3 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGR30931.1 - 3.5e-12 46.5 16.5 0.062 13.7 0.1 4.7 4 1 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGR30931.1 - 6.2e-11 42.4 11.5 0.27 11.3 0.0 5.6 4 4 1 5 5 5 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGR30931.1 - 4.4e-10 40.1 9.0 0.71 10.5 0.1 5.2 1 1 2 5 5 5 4 DUF2407 ubiquitin-like domain Big_7 PF17957.1 EGR30931.1 - 8.7e-10 39.2 0.0 3.6 8.4 0.0 4.2 4 0 0 4 4 4 4 Bacterial Ig domain UDP-g_GGTase PF06427.11 EGR30931.1 - 7.8e-06 26.0 9.1 5.4 7.2 0.0 4.3 4 0 0 4 4 4 3 UDP-glucose:Glycoprotein Glucosyltransferase DUF2870 PF11069.8 EGR30931.1 - 1.7e-05 25.1 2.0 33 5.0 0.0 5.3 5 0 0 5 5 4 0 Protein of unknown function (DUF2870) Big_3_3 PF13750.6 EGR30931.1 - 7.3e-05 22.5 0.1 3.6 7.2 0.0 4.0 3 1 0 3 3 3 1 Bacterial Ig-like domain (group 3) DUF3861 PF12977.7 EGR30931.1 - 0.00029 20.9 4.3 28 5.0 0.0 4.5 4 1 0 4 4 4 0 Domain of Unknown Function with PDB structure (DUF3861) DUF969 PF06149.12 EGR30931.1 - 0.00053 19.5 0.0 24 4.2 0.0 4.0 4 0 0 4 4 4 0 Protein of unknown function (DUF969) ACT_5 PF13710.6 EGR30931.1 - 0.0092 15.8 3.3 73 3.3 0.1 4.3 4 0 0 4 4 4 0 ACT domain ProRS-C_2 PF09181.10 EGR30931.1 - 0.016 15.3 4.8 79 3.5 0.1 4.3 4 0 0 4 4 4 0 Prolyl-tRNA synthetase, C-terminal ORF11CD3 PF10549.9 EGR30931.1 - 0.044 13.9 3.8 1e+02 3.1 0.0 5.0 5 0 0 5 5 4 0 ORF11CD3 domain Ntox21 PF15526.6 EGR30931.1 - 0.086 13.2 0.4 1.7e+02 2.6 0.5 4.0 4 0 0 4 4 4 0 Novel toxin 21 DUF3435 PF11917.8 EGR30931.1 - 0.11 11.4 4.0 2.1 7.2 1.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3435) FlgD_ig PF13860.6 EGR30931.1 - 0.14 12.0 9.0 60 3.6 0.1 4.3 4 0 0 4 4 4 0 FlgD Ig-like domain Ubiquitin_4 PF18036.1 EGR30931.1 - 0.29 11.2 34.7 28 4.9 0.0 8.4 9 0 0 9 9 8 0 Ubiquitin-like domain DUF4959 PF16323.5 EGR30931.1 - 0.8 10.1 3.3 4.4 7.7 0.9 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4959) Herpes_UL92 PF03048.14 EGR30931.1 - 0.82 9.4 3.0 12 5.7 1.4 3.1 4 0 0 4 4 4 0 UL92 family Hom_end_hint PF05203.16 EGR30931.1 - 3.6 7.5 6.2 6.6 6.6 2.5 2.9 4 0 0 4 4 4 0 Hom_end-associated Hint DUF5077 PF16871.5 EGR30931.1 - 9.7 6.0 8.9 22 4.9 4.1 3.1 1 1 3 4 4 4 0 Domain of unknown function (DUF5077) Gpi1 PF05024.15 EGR30932.1 - 2.1e-39 135.6 17.5 2.1e-39 135.6 17.5 2.6 3 0 0 3 3 3 1 N-acetylglucosaminyl transferase component (Gpi1) FGGY_N PF00370.21 EGR30933.1 - 3.4e-36 125.0 0.9 2.8e-32 112.2 0.5 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EGR30933.1 - 3.8e-33 114.9 0.0 1.3e-32 113.1 0.0 1.7 1 1 1 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Il2rg PF15874.5 EGR30933.1 - 0.011 16.0 0.6 0.059 13.6 0.1 2.2 2 0 0 2 2 2 0 Putative Interleukin 2 receptor, gamma chain NDK PF00334.19 EGR30933.1 - 0.08 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Nucleoside diphosphate kinase TPH PF13868.6 EGR30934.1 - 4.9e-06 25.3 53.3 4.9e-06 25.3 53.3 2.7 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain ATP_bind_1 PF03029.17 EGR30935.1 - 8.7e-77 258.2 1.2 1e-76 257.9 1.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_31 PF13614.6 EGR30935.1 - 0.0045 16.9 1.9 0.19 11.6 0.1 2.9 2 1 0 2 2 2 1 AAA domain CLP1_P PF16575.5 EGR30935.1 - 0.01 15.7 0.0 0.065 13.0 0.0 2.1 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_24 PF13479.6 EGR30935.1 - 0.012 15.3 0.0 0.032 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGR30935.1 - 0.014 15.3 0.6 0.95 9.3 0.1 2.7 2 1 0 2 2 2 0 RsgA GTPase Gtr1_RagA PF04670.12 EGR30935.1 - 0.017 14.5 0.7 0.42 9.9 0.7 2.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region ACT_4 PF13291.6 EGR30935.1 - 0.018 15.6 0.0 0.84 10.3 0.0 2.4 2 0 0 2 2 2 0 ACT domain AAA_10 PF12846.7 EGR30935.1 - 0.052 12.5 0.1 0.11 11.5 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain Cytidylate_kin PF02224.18 EGR30935.1 - 0.12 12.0 0.1 0.63 9.7 0.0 2.0 2 1 1 3 3 3 0 Cytidylate kinase AAA_18 PF13238.6 EGR30935.1 - 0.6 10.7 4.7 2 9.0 0.1 3.1 2 2 1 3 3 3 0 AAA domain Dopey_N PF04118.14 EGR30936.1 - 8.9e-28 97.3 13.6 8.9e-28 97.3 13.6 5.5 4 2 0 4 4 4 1 Dopey, N-terminal HEAT PF02985.22 EGR30936.1 - 0.016 15.4 0.3 3.1 8.3 0.1 3.5 3 0 0 3 3 3 0 HEAT repeat FANCI_HD1 PF14679.6 EGR30936.1 - 0.22 11.5 5.8 0.45 10.5 0.0 4.7 4 1 1 5 5 5 0 FANCI helical domain 1 Vac14_Fab1_bd PF12755.7 EGR30936.1 - 2.4 8.8 6.4 7.2 7.3 0.1 5.0 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region TRADD_N PF09034.10 EGR30937.1 - 0.48 10.5 3.0 0.52 10.4 2.6 1.3 1 1 0 1 1 1 0 TRADD, N-terminal domain NIF PF03031.18 EGR30938.1 - 8.6e-45 152.3 0.2 2.2e-44 150.9 0.1 1.6 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Kelch_3 PF13415.6 EGR30939.1 - 3.9e-20 71.6 7.4 2.3e-07 30.9 0.1 4.3 4 2 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EGR30939.1 - 4.2e-17 61.7 3.0 0.00027 20.8 0.0 4.3 4 0 0 4 4 4 4 Kelch motif Kelch_4 PF13418.6 EGR30939.1 - 6.5e-13 48.5 6.2 6.2e-05 22.9 0.1 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EGR30939.1 - 2.9e-11 43.2 5.6 0.0043 17.3 0.1 4.4 3 1 1 4 4 4 3 Kelch motif Kelch_1 PF01344.25 EGR30939.1 - 1.5e-08 34.1 8.8 0.00036 20.1 0.1 4.3 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 EGR30939.1 - 1e-07 31.7 4.0 0.0016 18.3 0.1 4.3 4 0 0 4 4 4 2 Kelch motif LMBR1 PF04791.16 EGR30939.1 - 5.4 5.8 13.9 7.4 5.4 13.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.12 EGR30939.1 - 9.8 6.2 13.8 2.4 8.2 3.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) Synaptobrevin PF00957.21 EGR30940.1 - 3.9e-12 45.8 1.5 3.9e-12 45.8 1.5 1.8 1 1 1 2 2 2 1 Synaptobrevin DUF3818 PF12825.7 EGR30940.1 - 0.0016 17.6 3.2 0.0022 17.1 3.2 1.1 1 0 0 1 1 1 1 Domain of unknown function in PX-proteins (DUF3818) Sec8_exocyst PF04048.14 EGR30940.1 - 0.04 13.8 7.1 0.2 11.6 3.5 2.0 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DUF1474 PF07342.11 EGR30940.1 - 0.047 14.2 2.6 0.057 14.0 0.9 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1474) Nab1 PF04902.12 EGR30940.1 - 0.056 13.8 3.9 0.079 13.4 3.9 1.2 1 0 0 1 1 1 0 Conserved region in Nab1 GldM_N PF12081.8 EGR30940.1 - 0.24 11.4 7.1 0.11 12.6 2.5 2.0 1 1 1 2 2 2 0 GldM N-terminal domain XhlA PF10779.9 EGR30940.1 - 2.1 8.6 5.7 1 9.6 1.6 2.2 1 1 1 2 2 2 0 Haemolysin XhlA Peptidase_M1 PF01433.20 EGR30941.1 - 8.6e-42 143.1 1.2 1.4e-41 142.5 1.2 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EGR30941.1 - 9.9e-27 93.3 0.6 2.1e-26 92.2 0.6 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EGR30941.1 - 2.6e-16 60.3 1.2 5.1e-16 59.4 1.2 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Tap-RNA_bind PF09162.10 EGR30941.1 - 0.063 13.1 2.4 0.86 9.5 0.1 2.6 2 0 0 2 2 2 0 Tap, RNA-binding EF-hand_7 PF13499.6 EGR30942.1 - 6.3e-10 39.4 0.6 6.3e-10 39.4 0.6 2.4 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGR30942.1 - 5.7e-08 32.1 4.7 0.0047 16.8 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 EGR30942.1 - 1.7e-07 30.3 11.7 3.2e-05 23.1 1.4 3.3 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 EGR30942.1 - 7e-06 25.3 5.5 0.019 14.4 0.0 3.2 3 0 0 3 3 3 2 EF hand HAD_SAK_2 PF18143.1 EGR30942.1 - 0.012 16.0 0.6 0.022 15.1 0.6 1.4 1 0 0 1 1 1 0 HAD domain in Swiss Army Knife RNA repair proteins PhnJ PF06007.11 EGR30942.1 - 0.025 13.6 0.1 0.039 13.0 0.1 1.3 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnJ SPARC_Ca_bdg PF10591.9 EGR30942.1 - 0.038 14.3 3.8 0.077 13.3 3.6 1.8 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region T7SS_ESX1_EccB PF05108.13 EGR30942.1 - 0.14 10.8 0.1 0.18 10.4 0.1 1.1 1 0 0 1 1 1 0 Type VII secretion system ESX-1, transport TM domain B Phytochelatin PF05023.14 EGR30942.1 - 0.18 11.0 1.4 10 5.3 0.0 2.1 2 0 0 2 2 2 0 Phytochelatin synthase EF-hand_8 PF13833.6 EGR30942.1 - 0.27 11.1 8.1 2 8.3 0.6 3.8 3 1 2 5 5 5 0 EF-hand domain pair V_ATPase_I PF01496.19 EGR30943.1 - 1.9e-74 251.0 18.5 4.5e-72 243.2 18.5 2.0 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family Cut8 PF08559.10 EGR30943.1 - 0.0075 15.9 3.3 0.0075 15.9 3.3 2.5 3 0 0 3 3 3 1 Cut8, nuclear proteasome tether protein L51_S25_CI-B8 PF05047.16 EGR30943.1 - 0.1 12.5 0.1 0.33 10.9 0.1 1.9 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain ComA PF02679.15 EGR30943.1 - 0.11 12.0 3.1 0.07 12.6 1.1 1.6 2 0 0 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) LAGLIDADG_WhiA PF14527.6 EGR30943.1 - 0.22 11.6 4.0 0.57 10.3 0.4 2.9 2 1 0 2 2 2 0 WhiA LAGLIDADG-like domain Uteroglobin PF01099.17 EGR30943.1 - 1.5 9.2 7.2 0.56 10.6 1.9 2.7 2 0 0 2 2 2 0 Uteroglobin family DUF4889 PF16230.5 EGR30943.1 - 2.9 8.2 5.4 0.87 9.9 1.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4889) Exonuc_VII_L PF02601.15 EGR30943.1 - 4.1 6.9 7.6 0.61 9.6 2.8 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 EGR30944.1 - 2.4e-68 230.9 1.2 3.2e-68 230.5 1.2 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Hydrolase_4 PF12146.8 EGR30944.1 - 1.1e-45 155.7 0.0 5.5e-45 153.5 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR30944.1 - 6.2e-11 42.4 0.1 1.4e-09 37.9 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGR30944.1 - 3.9e-07 30.9 0.0 5.9e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EGR30944.1 - 5.9e-05 23.3 3.3 6.2e-05 23.2 0.0 2.0 2 0 0 2 2 2 1 Thioesterase domain Lipase_3 PF01764.25 EGR30944.1 - 0.048 13.5 0.1 0.14 12.0 0.0 1.9 2 0 0 2 2 2 0 Lipase (class 3) EMC3_TMCO1 PF01956.16 EGR30944.1 - 0.05 13.3 0.8 0.15 11.8 0.8 1.8 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Peptidase_S15 PF02129.18 EGR30944.1 - 0.056 13.0 0.3 1.1 8.8 0.0 2.5 3 0 0 3 3 3 0 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 EGR30944.1 - 0.099 12.3 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) TPR_2 PF07719.17 EGR30945.1 - 1.5e-05 24.7 0.9 0.36 11.1 0.0 3.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGR30945.1 - 0.00031 20.4 0.7 2.2 8.2 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF1977 PF09320.11 EGR30945.1 - 0.058 13.7 3.8 0.058 13.7 0.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1977) NAD_kinase PF01513.21 EGR30946.1 - 3.9e-26 91.9 0.2 4.8e-26 91.6 0.2 1.0 1 0 0 1 1 1 1 ATP-NAD kinase Snf7 PF03357.21 EGR30948.1 - 6.6e-09 35.6 22.3 6.6e-09 35.6 22.3 1.8 1 1 1 2 2 2 1 Snf7 Aminotran_4 PF01063.19 EGR30948.1 - 0.014 15.3 0.2 0.018 14.9 0.2 1.2 1 0 0 1 1 1 0 Amino-transferase class IV BSP_II PF05432.11 EGR30948.1 - 0.015 15.0 3.4 0.021 14.5 3.4 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Alkyl_sulf_dimr PF14863.6 EGR30948.1 - 0.11 13.0 0.2 0.6 10.6 0.1 2.1 1 1 1 2 2 2 0 Alkyl sulfatase dimerisation CLZ PF16526.5 EGR30948.1 - 0.13 12.7 0.2 0.13 12.7 0.2 3.2 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CelTOS PF18659.1 EGR30948.1 - 0.33 11.4 7.1 0.34 11.4 0.1 2.6 2 1 0 2 2 2 0 Cell-traversal protein for ookinetes and sporozoites DUF2703 PF10865.8 EGR30948.1 - 0.39 10.9 7.8 0.59 10.3 1.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2703) Cauli_DNA-bind PF03310.13 EGR30948.1 - 0.84 9.7 14.1 2.9 8.0 1.0 2.8 1 1 2 3 3 3 0 Caulimovirus DNA-binding protein DUF3800 PF12686.7 EGR30948.1 - 0.96 10.1 4.5 1.6 9.4 4.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) IMD PF08397.11 EGR30948.1 - 1.4 8.3 12.3 0.21 11.0 5.9 2.1 1 1 2 3 3 3 0 IRSp53/MIM homology domain PPV_E1_N PF00524.18 EGR30948.1 - 5.2 7.5 7.1 1 9.8 1.7 2.2 2 0 0 2 2 2 0 E1 Protein, N terminal domain Myb_DNA-bind_4 PF13837.6 EGR30948.1 - 7.3 7.0 7.9 2 8.8 0.2 2.4 2 1 0 2 2 2 0 Myb/SANT-like DNA-binding domain Ribosomal_S17_N PF16205.5 EGR30949.1 - 1.8e-32 111.5 0.5 3.2e-32 110.7 0.5 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EGR30949.1 - 1.9e-24 85.6 0.5 2.8e-24 85.0 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Sec1 PF00995.23 EGR30950.1 - 1.2e-23 84.2 5.2 1.2e-23 84.2 5.2 1.9 1 1 1 2 2 2 1 Sec1 family baeRF_family8 PF18851.1 EGR30950.1 - 0.033 14.3 0.3 0.088 12.9 0.1 1.8 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 8 IFT57 PF10498.9 EGR30951.1 - 3.5e-84 282.9 41.7 9.3e-68 228.8 23.4 2.9 1 1 2 3 3 3 2 Intra-flagellar transport protein 57 Transcrip_act PF04949.13 EGR30951.1 - 0.0013 18.6 7.4 0.0013 18.6 7.4 3.0 3 1 1 4 4 4 1 Transcriptional activator PilJ PF13675.6 EGR30951.1 - 0.082 12.9 1.2 3.4 7.7 0.1 2.5 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DSX_dimer PF08828.10 EGR30951.1 - 0.11 12.2 1.0 0.35 10.6 1.0 1.8 1 0 0 1 1 1 0 Doublesex dimerisation domain Baculo_PEP_C PF04513.12 EGR30951.1 - 0.21 11.6 5.9 1 9.4 0.1 2.8 1 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 EGR30951.1 - 0.23 11.7 6.1 0.88 9.9 0.3 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 EGR30951.1 - 0.29 11.2 22.2 0.4 10.7 0.9 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) PRD PF00874.20 EGR30951.1 - 0.85 10.0 9.2 0.11 12.8 1.4 3.3 2 2 1 3 3 3 0 PRD domain DUF1515 PF07439.11 EGR30951.1 - 1.9 8.5 6.1 0.5 10.4 0.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1515) Exonuc_VII_L PF02601.15 EGR30951.1 - 4.2 6.9 18.6 87 2.5 17.7 2.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Laminin_II PF06009.12 EGR30951.1 - 7.2 6.6 19.6 2.7 8.0 8.4 3.3 2 1 1 3 3 3 0 Laminin Domain II Furin-like_2 PF15913.5 EGR30952.1 - 0.00064 19.9 15.2 0.00064 19.9 15.2 6.5 1 1 5 6 6 6 2 Furin-like repeat, cysteine-rich VSP PF03302.13 EGR30952.1 - 1.6 7.5 84.7 0.015 14.2 24.4 4.1 1 1 3 4 4 4 0 Giardia variant-specific surface protein Ras PF00071.22 EGR30953.1 - 8.1e-47 158.8 0.0 1.1e-46 158.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR30953.1 - 5.9e-31 107.2 0.1 1.5e-30 105.9 0.1 1.7 2 0 0 2 2 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR30953.1 - 5.2e-13 48.8 0.2 5.2e-13 48.8 0.2 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family G-alpha PF00503.20 EGR30953.1 - 7.2e-05 22.1 1.1 0.0023 17.2 0.2 2.2 2 0 0 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 EGR30953.1 - 0.0001 22.3 0.1 0.00027 21.0 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGR30953.1 - 0.0024 17.8 0.3 0.04 13.8 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EGR30953.1 - 0.0031 17.0 0.0 0.007 15.8 0.0 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MCM PF00493.23 EGR30953.1 - 0.004 16.3 0.2 0.0073 15.4 0.0 1.5 2 0 0 2 2 2 1 MCM P-loop domain Gtr1_RagA PF04670.12 EGR30953.1 - 0.0049 16.2 0.0 0.0097 15.3 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_7 PF12775.7 EGR30953.1 - 0.0057 16.2 0.3 0.01 15.4 0.3 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region PduV-EutP PF10662.9 EGR30953.1 - 0.0058 16.4 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Septin PF00735.18 EGR30953.1 - 0.02 14.2 0.2 0.11 11.7 0.1 2.1 2 0 0 2 2 2 0 Septin TsaE PF02367.17 EGR30953.1 - 0.023 14.7 0.0 0.052 13.6 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 EGR30953.1 - 0.024 14.3 0.1 0.045 13.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain Pox_A32 PF04665.12 EGR30953.1 - 0.048 13.1 0.0 0.083 12.3 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A32 protein RNA_helicase PF00910.22 EGR30953.1 - 0.092 13.1 0.5 2.7 8.4 0.5 2.4 1 1 0 1 1 1 0 RNA helicase ATP_bind_1 PF03029.17 EGR30953.1 - 0.16 11.8 0.5 9.4 5.9 0.1 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein eRF1_2 PF03464.15 EGR30954.1 - 6.3e-37 126.9 0.2 6.3e-37 126.9 0.2 1.8 2 0 0 2 2 2 1 eRF1 domain 2 eRF1_3 PF03465.15 EGR30954.1 - 1e-32 113.0 0.2 3.5e-32 111.2 0.2 1.9 2 0 0 2 2 2 1 eRF1 domain 3 eRF1_1 PF03463.15 EGR30954.1 - 5e-06 26.5 0.1 1.1e-05 25.4 0.1 1.6 1 0 0 1 1 1 1 eRF1 domain 1 acVLRF1 PF18859.1 EGR30954.1 - 0.00027 21.2 0.0 0.00046 20.5 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 EGR30954.1 - 0.17 12.1 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 RPN7 PF10602.9 EGR30955.1 - 1.9e-37 128.6 7.5 4.9e-37 127.3 7.5 1.7 1 1 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EGR30955.1 - 1.4e-15 57.6 0.3 1.4e-15 57.6 0.3 2.5 3 1 0 3 3 3 1 PCI domain TPR_7 PF13176.6 EGR30955.1 - 0.003 17.5 0.2 0.071 13.2 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGR30955.1 - 0.0044 17.1 1.6 0.15 12.3 0.3 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGR30955.1 - 0.15 12.0 0.3 0.15 12.0 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGR30955.1 - 0.37 11.0 1.5 2.2 8.6 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Guanylate_cyc PF00211.20 EGR30957.1 - 8.1e-14 51.7 1.2 1.4e-13 50.9 0.1 1.9 2 0 0 2 2 2 1 Adenylate and Guanylate cyclase catalytic domain Kinesin PF00225.23 EGR30958.1 - 1e-92 310.6 12.4 1e-92 310.6 12.4 4.9 4 2 0 5 5 5 2 Kinesin motor domain Microtub_bd PF16796.5 EGR30958.1 - 5.6e-17 62.0 3.4 5.6e-17 62.0 3.4 7.1 5 2 2 7 7 7 1 Microtubule binding WD40 PF00400.32 EGR30958.1 - 0.0054 17.6 0.0 0.41 11.6 0.0 2.8 2 0 0 2 2 2 1 WD domain, G-beta repeat HSP70 PF00012.20 EGR30959.1 - 3.6e-42 144.4 13.1 1.3e-25 89.7 0.3 3.2 2 1 0 3 3 3 3 Hsp70 protein AlbA_2 PF04326.14 EGR30959.1 - 1.2e-16 61.1 1.3 1.2e-16 61.1 1.3 3.0 3 0 0 3 3 3 1 Putative DNA-binding domain Peptidase_M20 PF01546.28 EGR30960.1 - 5.1e-20 72.0 0.0 6.7e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGR30960.1 - 1.3e-09 38.0 0.0 2.3e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Spindle_Spc25 PF08234.12 EGR30960.1 - 0.11 12.7 0.1 0.63 10.3 0.1 2.1 2 0 0 2 2 2 0 Chromosome segregation protein Spc25 UBA PF00627.31 EGR30961.1 - 3.7e-18 65.1 4.7 7.1e-10 38.6 0.2 2.8 3 0 0 3 3 3 2 UBA/TS-N domain XPC-binding PF09280.11 EGR30961.1 - 8e-17 60.7 20.1 8e-17 60.7 20.1 2.3 2 0 0 2 2 1 1 XPC-binding domain ubiquitin PF00240.23 EGR30961.1 - 1.2e-12 47.3 2.4 3.7e-12 45.8 2.4 1.9 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGR30961.1 - 5.3e-07 29.4 3.7 5.3e-07 29.4 3.7 3.1 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.10 EGR30961.1 - 5.1e-05 23.0 0.6 0.0034 17.2 0.1 3.1 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain Rad60-SLD_2 PF13881.6 EGR30961.1 - 0.00011 22.3 0.7 0.00026 21.1 0.7 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGR30961.1 - 0.00033 21.2 3.1 0.00041 20.9 1.0 2.2 2 1 0 2 2 2 1 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EGR30961.1 - 0.0036 17.3 1.5 0.82 9.8 1.5 3.0 1 1 0 1 1 1 1 Ubiquitin-like domain CUE PF02845.16 EGR30961.1 - 0.0037 16.9 0.1 0.18 11.6 0.0 2.9 2 0 0 2 2 2 1 CUE domain STI1 PF17830.1 EGR30961.1 - 0.028 14.3 1.4 0.028 14.3 1.4 4.4 3 1 1 4 4 4 0 STI1 domain Ubiquitin_5 PF18037.1 EGR30961.1 - 0.23 11.8 9.9 0.041 14.2 2.5 2.7 2 0 0 2 2 2 0 Ubiquitin-like domain YlzJ PF14035.6 EGR30961.1 - 3.8 7.8 8.0 5.7 7.2 0.0 3.7 2 1 1 3 3 3 0 YlzJ-like protein UCH PF00443.29 EGR30963.1 - 4.2e-39 134.6 11.2 1e-38 133.4 11.2 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RICTOR_V PF14668.6 EGR30963.1 - 2.1e-21 75.9 3.1 6.1e-21 74.4 0.5 2.7 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 UCH_1 PF13423.6 EGR30963.1 - 4.5e-17 62.6 13.2 5.1e-17 62.5 7.9 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_4 PF18036.1 EGR30963.1 - 0.059 13.4 2.2 5.1 7.2 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin-like domain NapB PF03892.14 EGR30963.1 - 0.065 13.2 1.8 0.26 11.3 1.8 2.0 1 0 0 1 1 1 0 Nitrate reductase cytochrome c-type subunit (NapB) RA PF00788.23 EGR30963.1 - 0.11 13.2 2.2 0.18 12.5 0.6 2.3 2 0 0 2 2 2 0 Ras association (RalGDS/AF-6) domain RasGEF_N_2 PF14663.6 EGR30964.1 - 1.2e-23 83.6 2.5 1.2e-23 83.6 2.5 3.5 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_M PF14666.6 EGR30964.1 - 2.2e-21 75.5 0.4 2.2e-21 75.5 0.4 3.3 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RICTOR_N PF14664.6 EGR30964.1 - 2e-08 33.6 8.6 6.5e-06 25.4 0.1 3.4 3 1 1 4 4 4 2 Rapamycin-insensitive companion of mTOR, N-term DUF1064 PF06356.11 EGR30964.1 - 0.46 10.9 9.1 0.12 12.7 2.9 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1064) GST_C_6 PF17171.4 EGR30964.1 - 3.7 7.4 5.8 14 5.5 0.0 3.7 3 1 1 4 4 4 0 Glutathione S-transferase, C-terminal domain HU-CCDC81_euk_1 PF14908.6 EGR30965.1 - 9.3e-32 109.1 0.1 1.9e-31 108.0 0.1 1.5 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 EGR30965.1 - 6.3e-10 39.1 0.1 1.5e-09 37.8 0.1 1.7 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 2 Bac_DNA_binding PF00216.21 EGR30965.1 - 0.024 14.8 0.1 0.073 13.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial DNA-binding protein CRAL_TRIO PF00650.20 EGR30965.1 - 0.048 13.4 0.5 0.16 11.7 0.0 1.9 2 0 0 2 2 2 0 CRAL/TRIO domain HU-HIG PF18291.1 EGR30965.1 - 0.058 13.5 0.0 0.44 10.7 0.0 2.5 2 1 0 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif Pkinase PF00069.25 EGR30967.1 - 1e-10 41.5 1.1 1.1e-10 41.3 0.3 1.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30967.1 - 3.8e-08 32.9 0.5 4.3e-08 32.8 0.5 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Sacchrp_dh_C PF16653.5 EGR30969.1 - 7.3e-81 272.2 0.0 1.1e-80 271.6 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EGR30969.1 - 2.1e-17 63.6 0.3 9.4e-17 61.5 0.0 2.1 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Shikimate_DH PF01488.20 EGR30969.1 - 5.9e-06 26.4 0.1 1.2e-05 25.4 0.1 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DapB_N PF01113.20 EGR30969.1 - 0.085 13.0 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_10 PF13460.6 EGR30969.1 - 0.14 12.0 0.0 0.42 10.5 0.0 1.7 1 1 1 2 2 2 0 NAD(P)H-binding PAS PF00989.25 EGR30970.1 - 0.062 13.3 0.1 0.37 10.8 0.0 2.4 2 0 0 2 2 2 0 PAS fold PAS_9 PF13426.7 EGR30970.1 - 0.19 12.0 2.3 0.44 10.8 0.0 3.0 3 0 0 3 3 3 0 PAS domain CD225 PF04505.12 EGR30970.1 - 2.6 8.2 5.1 6.2 7.0 1.1 2.9 2 0 0 2 2 2 0 Interferon-induced transmembrane protein WD40 PF00400.32 EGR30971.1 - 7.5e-30 102.6 25.3 8.1e-06 26.5 0.6 10.7 11 0 0 11 11 11 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR30971.1 - 2.5e-16 59.8 7.9 0.00052 20.2 0.1 7.7 4 4 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGR30971.1 - 0.00015 21.7 9.0 0.14 12.0 0.0 4.2 3 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 EGR30971.1 - 0.011 15.3 0.0 0.36 10.4 0.0 3.0 2 2 1 4 4 4 0 PQQ-like domain PQQ PF01011.21 EGR30971.1 - 0.012 15.5 0.8 0.75 9.8 0.0 4.0 4 0 0 4 4 4 0 PQQ enzyme repeat HEAT PF02985.22 EGR30972.1 - 0.0039 17.3 0.1 2.1 8.8 0.0 2.7 2 0 0 2 2 2 2 HEAT repeat SeqA_N PF17206.3 EGR30972.1 - 0.06 12.7 0.1 0.17 11.2 0.1 1.8 1 0 0 1 1 1 0 SeqA protein N-terminal domain Ribosomal_L41 PF05162.13 EGR30975.1 - 0.00042 20.3 28.8 0.00065 19.7 28.8 1.3 1 0 0 1 1 1 1 Ribosomal protein L41 Thioredoxin PF00085.20 EGR30976.1 - 4.8e-12 45.8 3.1 8.4e-07 28.9 0.0 3.2 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_7 PF13899.6 EGR30976.1 - 0.0082 16.3 0.1 0.024 14.8 0.1 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EGR30976.1 - 0.022 15.2 0.6 1.4 9.4 0.0 3.5 3 0 0 3 3 3 0 Thioredoxin-like domain EPOP PF15223.6 EGR30976.1 - 0.031 13.7 10.4 0.046 13.1 10.4 1.2 1 0 0 1 1 1 0 Elongin BC and Polycomb repressive complex 2-associated protein FAM27 PF15832.5 EGR30976.1 - 0.28 11.7 1.7 0.55 10.8 1.7 1.4 1 0 0 1 1 1 0 FAM27 D and E protein family MRP-L46 PF11788.8 EGR30976.1 - 1.4 9.7 13.0 47 4.7 0.0 3.1 2 0 0 2 2 2 0 39S mitochondrial ribosomal protein L46 KfrA_N PF11740.8 EGR30977.1 - 0.083 13.6 3.8 0.36 11.5 3.8 2.2 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term Pkinase PF00069.25 EGR30978.1 - 3.5e-75 252.8 0.1 5.9e-75 252.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30978.1 - 3.3e-36 124.9 0.1 1.4e-35 122.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase FTA2 PF13095.6 EGR30978.1 - 0.00044 19.9 0.9 0.017 14.7 0.4 2.4 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EGR30978.1 - 0.00069 19.0 0.0 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.24 EGR30978.1 - 0.0012 19.5 0.0 0.0023 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase C terminal domain PAS_9 PF13426.7 EGR30981.1 - 0.0036 17.5 0.1 0.0036 17.5 0.1 4.2 4 1 2 6 6 6 1 PAS domain Pescadillo_N PF06732.11 EGR30982.1 - 2.1e-109 365.3 14.7 4.8e-109 364.1 14.1 1.8 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 EGR30982.1 - 2.7e-11 43.7 0.0 9.3e-11 42.0 0.0 2.0 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGR30982.1 - 4.8e-07 30.1 0.1 4.8e-07 30.1 0.1 3.3 4 0 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EGR30982.1 - 2.6e-05 24.4 0.2 9.2e-05 22.7 0.0 2.1 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain ACDC PF14733.6 EGR30982.1 - 0.065 13.6 0.0 0.27 11.6 0.0 2.1 1 0 0 1 1 1 0 AP2-coincident C-terminal Pkinase PF00069.25 EGR30983.1 - 2.7e-74 249.9 0.3 4.6e-74 249.1 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30983.1 - 5.3e-39 134.0 0.0 8.9e-39 133.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Myosin_TH1 PF06017.13 EGR30983.1 - 2.6e-12 46.8 2.7 6.4e-12 45.5 2.7 1.7 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding Kinase-like PF14531.6 EGR30983.1 - 2.4e-06 27.1 0.0 8.7e-06 25.2 0.0 1.8 1 1 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 EGR30983.1 - 0.0013 19.4 0.4 0.0032 18.2 0.4 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_3 PF14593.6 EGR30983.1 - 0.0033 17.5 0.1 0.018 15.2 0.1 2.3 1 1 0 1 1 1 1 PH domain MxiM PF11441.8 EGR30983.1 - 0.049 13.9 3.2 0.19 12.1 0.1 2.9 2 0 0 2 2 2 0 Pilot protein MxiM BBS1 PF14779.6 EGR30984.1 - 1.4e-54 185.2 3.0 2.9e-54 184.2 3.0 1.5 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 1 CAF1 PF04857.20 EGR30984.1 - 6.6e-19 68.2 0.4 6.6e-19 68.2 0.4 1.5 2 0 0 2 2 2 1 CAF1 family ribonuclease BBS2_Mid PF14783.6 EGR30984.1 - 6.2e-05 23.0 3.1 0.0091 16.0 0.0 3.4 3 1 1 4 4 4 2 Ciliary BBSome complex subunit 2, middle region NEL PF14496.6 EGR30984.1 - 0.11 11.8 0.8 2 7.8 0.0 2.7 3 0 0 3 3 3 0 C-terminal novel E3 ligase, LRR-interacting DUF5625 PF18539.1 EGR30984.1 - 0.6 10.4 5.0 11 6.4 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5625) zf-LITAF-like PF10601.9 EGR30985.1 - 7.9e-17 61.3 2.8 9e-17 61.1 2.8 1.0 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain AA_permease_C PF13906.6 EGR30985.1 - 0.011 15.8 0.1 0.018 15.1 0.1 1.3 1 0 0 1 1 1 0 C-terminus of AA_permease Trehalose_PPase PF02358.16 EGR30986.1 - 2.9e-14 52.8 0.1 4.1e-14 52.3 0.1 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Nt_Gln_amidase PF09764.9 EGR30986.1 - 0.0023 17.6 1.7 0.0074 15.9 1.7 1.8 1 1 0 1 1 1 1 N-terminal glutamine amidase Arm_3 PF16186.5 EGR30986.1 - 0.049 13.2 0.2 0.2 11.3 0.2 2.1 1 0 0 1 1 1 0 Atypical Arm repeat DUF1727 PF08353.10 EGR30986.1 - 0.052 13.5 0.2 0.89 9.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1727) cNMP_binding PF00027.29 EGR30987.1 - 4.1e-13 49.2 0.0 6.7e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGR30987.1 - 1.9e-12 47.0 2.5 1.9e-12 47.0 2.5 2.1 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 EGR30987.1 - 3.5e-11 42.8 1.2 6.3e-11 42.0 1.2 1.4 1 0 0 1 1 1 1 Ion transport protein Methyltransf_FA PF12248.8 EGR30987.1 - 1 9.7 6.0 1.8 9.0 0.2 3.3 3 1 0 3 3 3 0 Farnesoic acid 0-methyl transferase IQ PF00612.27 EGR30988.1 - 0.00033 20.2 0.3 0.001 18.7 0.3 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Peptidase_S11 PF00768.20 EGR30989.1 - 2.4e-35 122.1 1.5 2.4e-21 76.3 0.4 2.1 2 0 0 2 2 2 2 D-alanyl-D-alanine carboxypeptidase Arm PF00514.23 EGR30990.1 - 2.7e-34 116.1 16.0 6.3e-10 38.8 0.2 7.3 7 0 0 7 7 7 5 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EGR30990.1 - 8.6e-18 62.9 8.8 0.024 14.9 0.0 8.1 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.6 EGR30990.1 - 2.1e-15 56.9 15.8 0.00094 19.5 0.1 5.6 3 2 2 5 5 5 4 HEAT repeats HEAT_EZ PF13513.6 EGR30990.1 - 4.1e-12 46.3 15.5 1.5e-05 25.3 0.4 6.2 4 2 4 8 8 8 5 HEAT-like repeat Cnd1 PF12717.7 EGR30990.1 - 1.6e-10 41.3 3.8 0.04 14.0 0.2 4.2 1 1 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 DNA_alkylation PF08713.11 EGR30990.1 - 1.4e-06 28.2 1.2 0.74 9.5 0.0 4.3 3 1 1 4 4 4 2 DNA alkylation repair enzyme RICTOR_N PF14664.6 EGR30990.1 - 0.00053 19.1 4.0 0.0027 16.8 0.5 2.9 2 1 1 3 3 3 1 Rapamycin-insensitive companion of mTOR, N-term Atx10homo_assoc PF09759.9 EGR30990.1 - 0.0043 17.0 1.3 2.7 8.1 0.1 4.3 3 1 2 5 5 5 1 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 EGR30990.1 - 0.0053 16.2 1.4 3.5 7.0 0.0 3.5 3 1 1 4 4 4 2 Armadillo-like CHASE6_C PF17150.4 EGR30990.1 - 0.012 16.3 2.0 7.5 7.3 0.1 4.5 4 2 0 4 4 3 0 C-terminal domain of two-partite extracellular sensor domain Vac14_Fab1_bd PF12755.7 EGR30990.1 - 0.012 16.2 1.1 1.5 9.5 0.1 3.4 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region CelTOS PF18659.1 EGR30990.1 - 0.014 15.8 2.2 18 5.8 0.0 3.7 2 1 1 3 3 3 0 Cell-traversal protein for ookinetes and sporozoites CLASP_N PF12348.8 EGR30990.1 - 0.014 14.9 2.5 0.034 13.7 0.4 2.4 3 0 0 3 3 3 0 CLASP N terminal Adaptin_N PF01602.20 EGR30990.1 - 0.02 13.5 9.2 2 6.9 0.7 4.0 2 2 2 4 4 4 0 Adaptin N terminal region Proteasom_PSMB PF10508.9 EGR30990.1 - 0.023 13.2 6.3 0.15 10.5 0.1 3.4 1 1 2 4 4 4 0 Proteasome non-ATPase 26S subunit Mo25 PF08569.11 EGR30990.1 - 0.043 13.2 1.4 11 5.2 0.1 3.1 2 1 0 3 3 3 0 Mo25-like HEAT_PBS PF03130.16 EGR30990.1 - 0.053 14.2 17.6 0.72 10.7 0.9 6.1 7 1 0 7 7 6 0 PBS lyase HEAT-like repeat Pkinase PF00069.25 EGR30991.1 - 1.5e-65 221.2 4.7 1.5e-65 221.2 4.7 2.4 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30991.1 - 4.8e-31 108.0 0.9 4.8e-31 108.0 0.9 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EGR30991.1 - 5.1e-05 23.3 0.0 9e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR30991.1 - 6.3e-05 22.4 0.1 0.00015 21.2 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ANAPC4_WD40 PF12894.7 EGR30991.1 - 0.0004 20.6 0.2 0.017 15.4 0.1 3.4 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGR30991.1 - 0.00066 20.4 0.1 0.0036 18.1 0.1 2.3 2 0 0 2 2 2 1 WD domain, G-beta repeat Transposase_24 PF03004.14 EGR30991.1 - 0.051 13.7 1.9 0.12 12.4 1.9 1.6 1 0 0 1 1 1 0 Plant transposase (Ptta/En/Spm family) Cytochrome_C554 PF13435.6 EGR30991.1 - 7.6 7.5 8.1 2.8 8.9 0.0 3.4 3 0 0 3 3 3 0 Cytochrome c554 and c-prime Ribosomal_S13 PF00416.22 EGR30992.1 - 1.3e-45 154.9 0.4 1.5e-45 154.7 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Period_C PF12114.8 EGR30992.1 - 0.0055 16.3 0.0 0.0076 15.9 0.0 1.2 1 0 0 1 1 1 1 Period protein 2/3C-terminal region IMS_HHH PF11798.8 EGR30992.1 - 0.095 13.1 0.2 0.35 11.3 0.1 2.0 2 0 0 2 2 2 0 IMS family HHH motif FbpA PF05833.11 EGR30992.1 - 0.1 11.4 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) DUF1188 PF06690.11 EGR30992.1 - 0.12 11.9 0.2 0.85 9.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) H2TH PF06831.14 EGR30992.1 - 0.15 12.0 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Formamidopyrimidine-DNA glycosylase H2TH domain Pkinase PF00069.25 EGR30993.1 - 5.4e-55 186.6 0.0 6.5e-55 186.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR30993.1 - 3.4e-32 111.8 0.0 3.9e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR30993.1 - 1.2e-06 28.7 0.0 3.5e-06 27.1 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR30993.1 - 4e-06 26.3 0.0 5.3e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGR30993.1 - 1.6e-05 24.0 0.2 2.1e-05 23.7 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGR30993.1 - 1.7e-05 24.3 0.0 2.2e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR30993.1 - 0.00019 20.3 0.0 0.00024 20.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Choline_kinase PF01633.20 EGR30993.1 - 0.0013 18.4 0.7 0.0025 17.4 0.7 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 EGR30993.1 - 0.064 12.8 0.1 0.13 11.7 0.0 1.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL ADP_PFK_GK PF04587.15 EGR30993.1 - 0.13 10.8 0.3 0.18 10.3 0.3 1.1 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region MORN PF02493.20 EGR30994.1 - 7.5e-48 157.6 75.5 4.4e-07 29.4 1.8 13.0 13 0 0 13 13 13 12 MORN repeat LCCL PF03815.19 EGR30994.1 - 1.1 9.4 5.0 1.1 9.5 0.4 2.8 2 1 1 3 3 3 0 LCCL domain FAD_binding_6 PF00970.24 EGR30995.1 - 2.6e-21 75.8 0.1 3.3e-20 72.3 0.0 2.4 1 1 1 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGR30995.1 - 7.2e-06 26.6 0.1 1.7e-05 25.4 0.0 1.6 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EGR30995.1 - 2.3e-05 24.6 0.2 5.2e-05 23.4 0.2 1.6 1 0 0 1 1 1 1 Ferric reductase NAD binding domain DEAD PF00270.29 EGR30996.1 - 2.6 7.8 9.8 0.063 13.0 2.5 2.0 2 0 0 2 2 2 0 DEAD/DEAH box helicase Jacalin PF01419.17 EGR30997.1 - 0.014 15.3 0.3 0.037 14.0 0.2 1.8 1 1 0 1 1 1 0 Jacalin-like lectin domain FtsX_ECD PF18075.1 EGR30997.1 - 0.02 15.5 0.7 0.31 11.7 0.5 2.6 2 0 0 2 2 2 0 FtsX extracellular domain FBA PF04300.13 EGR30997.1 - 0.058 13.1 4.9 0.46 10.1 2.3 2.9 1 1 1 2 2 2 0 F-box associated region RIP PF00161.19 EGR30997.1 - 0.075 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Ribosome inactivating protein Neisseria_PilC PF05567.11 EGR30997.1 - 0.076 12.0 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Neisseria PilC beta-propeller domain Dynein_C PF18199.1 EGR30998.1 - 2.4e-102 342.3 0.0 3.5e-102 341.7 0.0 1.3 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_lid_11 PF18198.1 EGR30998.1 - 2.5e-61 206.3 0.2 4e-61 205.6 0.2 1.3 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGR30998.1 - 7.3e-43 145.4 0.1 1.7e-42 144.3 0.1 1.7 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_8 PF12780.7 EGR30999.1 - 6.4e-95 317.4 1.6 1.6e-94 316.1 1.6 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 EGR30999.1 - 1.4e-62 210.4 2.2 1.2e-61 207.4 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_9 PF12781.7 EGR30999.1 - 6.6e-62 208.5 0.5 6.6e-62 208.5 0.5 3.7 3 1 0 3 3 2 1 ATP-binding dynein motor region MT PF12777.7 EGR30999.1 - 4.8e-31 108.0 20.5 7.2e-31 107.5 20.5 1.2 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 EGR30999.1 - 1.2e-15 57.5 2.1 6.4e-15 55.2 0.8 2.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 EGR30999.1 - 8.1e-07 29.1 0.1 0.00095 19.2 0.0 3.5 3 1 1 4 4 3 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EGR30999.1 - 3.1e-05 24.4 1.9 0.00022 21.7 0.0 3.4 4 0 0 4 4 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGR30999.1 - 0.00011 22.7 6.9 0.00098 19.5 0.0 3.8 4 1 0 4 4 3 1 AAA ATPase domain DUF815 PF05673.13 EGR30999.1 - 0.00012 21.4 2.9 0.0078 15.4 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF815) T2SSE PF00437.20 EGR30999.1 - 0.0011 18.1 4.1 0.064 12.3 0.1 3.0 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_29 PF13555.6 EGR30999.1 - 0.0034 17.1 1.1 0.27 11.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EGR30999.1 - 0.0034 17.6 10.5 0.029 14.6 0.0 5.3 5 1 1 6 6 6 1 AAA domain RNA_helicase PF00910.22 EGR30999.1 - 0.0055 17.1 0.2 0.044 14.2 0.0 2.7 2 0 0 2 2 1 1 RNA helicase AAA_14 PF13173.6 EGR30999.1 - 0.0072 16.4 0.1 0.0072 16.4 0.1 4.1 4 0 0 4 4 4 1 AAA domain Sigma54_activat PF00158.26 EGR30999.1 - 0.0086 15.8 0.0 0.07 12.8 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_30 PF13604.6 EGR30999.1 - 0.019 14.7 3.2 0.078 12.7 0.0 3.1 4 0 0 4 4 4 0 AAA domain FtsK_SpoIIIE PF01580.18 EGR30999.1 - 0.019 14.3 1.8 0.12 11.7 0.0 2.8 3 0 0 3 3 3 0 FtsK/SpoIIIE family NACHT PF05729.12 EGR30999.1 - 0.03 14.3 0.1 0.084 12.8 0.1 1.8 1 0 0 1 1 1 0 NACHT domain DUF2075 PF09848.9 EGR30999.1 - 0.032 13.5 0.1 0.032 13.5 0.1 3.5 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) HMG_CoA_synt_C PF08540.10 EGR30999.1 - 0.036 13.7 4.7 0.045 13.4 0.3 2.6 3 0 0 3 3 2 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal AAA_19 PF13245.6 EGR30999.1 - 0.05 13.9 0.0 0.05 13.9 0.0 4.5 4 2 1 5 5 5 0 AAA domain RsgA_GTPase PF03193.16 EGR30999.1 - 0.059 13.3 3.8 0.31 10.9 0.1 3.5 3 0 0 3 3 3 0 RsgA GTPase APS_kinase PF01583.20 EGR30999.1 - 0.074 12.9 0.1 2.2 8.2 0.0 2.7 2 0 0 2 2 2 0 Adenylylsulphate kinase IstB_IS21 PF01695.17 EGR30999.1 - 0.077 12.7 0.0 0.077 12.7 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein TsaE PF02367.17 EGR30999.1 - 0.083 12.9 0.1 0.32 11.0 0.0 2.0 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EGR30999.1 - 0.089 13.3 16.2 0.18 12.4 0.1 5.0 5 0 0 5 5 5 0 ABC transporter Mg_chelatase PF01078.21 EGR30999.1 - 0.13 11.6 0.0 3.6 6.9 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Spc7 PF08317.11 EGR30999.1 - 0.19 10.6 36.0 0.0071 15.3 9.3 3.1 2 1 0 2 2 2 0 Spc7 kinetochore protein DASH_Duo1 PF08651.10 EGR30999.1 - 0.25 11.1 5.8 1.7 8.5 0.6 4.2 3 0 0 3 3 3 0 DASH complex subunit Duo1 Flagellin_N PF00669.20 EGR30999.1 - 0.44 10.7 5.5 1.9 8.6 2.4 2.9 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region ERM PF00769.19 EGR30999.1 - 0.51 10.1 23.4 0.099 12.4 4.2 2.4 2 0 0 2 2 2 0 Ezrin/radixin/moesin family AAA_18 PF13238.6 EGR30999.1 - 0.69 10.5 9.1 28 5.3 0.6 4.8 5 0 0 5 5 4 0 AAA domain AAA_6 PF12774.7 EGR31000.1 - 3.1e-152 506.2 0.0 9.9e-152 504.6 0.0 1.9 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGR31000.1 - 2.8e-111 372.5 28.5 2.8e-111 372.5 28.5 3.5 1 1 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 EGR31000.1 - 3.2e-07 30.4 1.2 0.0014 18.6 0.0 5.0 4 1 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGR31000.1 - 0.00014 22.4 4.3 0.0027 18.3 0.0 4.0 4 0 0 4 4 4 1 AAA domain AAA_7 PF12775.7 EGR31000.1 - 0.0012 18.4 0.3 2.4 7.6 0.1 3.0 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA PF00004.29 EGR31000.1 - 0.0035 17.7 1.2 0.16 12.4 0.0 4.0 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGR31000.1 - 0.0048 17.3 0.3 14 6.1 0.1 4.0 3 0 0 3 3 3 2 RNA helicase AAA_22 PF13401.6 EGR31000.1 - 0.032 14.5 1.9 17 5.6 0.0 3.8 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.6 EGR31000.1 - 0.066 13.4 0.0 2.4 8.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGR31000.1 - 0.098 13.0 0.0 3 8.2 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain DUF2730 PF10805.8 EGR31000.1 - 0.25 11.5 3.2 1.2 9.3 0.6 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) CSM2 PF16834.5 EGR31001.1 - 0.16 11.6 3.3 0.18 11.4 3.3 1.1 1 0 0 1 1 1 0 Shu complex component Csm2, DNA-binding Pkinase PF00069.25 EGR31003.1 - 2.2e-24 86.2 0.0 2.5e-24 86.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31003.1 - 1.8e-10 40.6 0.0 2.1e-10 40.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31003.1 - 0.003 16.9 0.0 0.0036 16.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like GerD PF17898.1 EGR31004.1 - 0.012 15.5 7.6 0.022 14.7 7.6 1.6 1 1 0 1 1 1 0 Spore germination GerD central core domain FPRL1_inhibitor PF16104.5 EGR31004.1 - 0.091 12.9 1.7 0.13 12.5 1.7 1.3 1 0 0 1 1 1 0 Formyl peptide receptor-like 1 inhibitory protein Wzz PF02706.15 EGR31004.1 - 3.8 7.9 10.5 0.26 11.6 2.1 2.2 1 1 1 2 2 2 0 Chain length determinant protein PK PF00224.21 EGR31005.1 - 1.1e-42 146.2 3.7 1.6e-42 145.6 3.7 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EGR31005.1 - 1.1e-22 80.5 0.4 3.6e-22 78.8 0.1 2.0 3 0 0 3 3 3 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EGR31005.1 - 4e-05 22.9 0.3 8.5e-05 21.8 0.3 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family TehB PF03848.14 EGR31005.1 - 0.027 13.9 3.1 0.029 13.8 0.3 2.2 2 1 0 2 2 2 0 Tellurite resistance protein TehB EF-hand_7 PF13499.6 EGR31006.1 - 1.9e-21 76.3 21.2 1.5e-10 41.3 0.5 5.1 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 EGR31006.1 - 7.5e-21 72.1 22.7 7.7e-05 22.0 0.2 6.8 6 0 0 6 6 6 5 EF hand EF-hand_8 PF13833.6 EGR31006.1 - 1.1e-20 73.2 14.9 1.6e-07 31.1 0.2 5.6 3 2 2 5 5 5 5 EF-hand domain pair EF-hand_6 PF13405.6 EGR31006.1 - 6.5e-17 60.0 18.6 0.0063 16.4 0.0 6.8 6 0 0 6 6 6 5 EF-hand domain EF-hand_5 PF13202.6 EGR31006.1 - 2.7e-11 42.4 15.0 0.0094 15.4 0.2 5.9 5 0 0 5 5 5 4 EF hand EF-hand_10 PF14788.6 EGR31006.1 - 0.0044 16.8 1.8 0.0044 16.8 1.8 5.0 4 0 0 4 4 4 1 EF hand EF-hand_11 PF08976.11 EGR31006.1 - 0.88 10.5 6.9 2.5 9.0 0.1 3.9 3 0 0 3 3 3 0 EF-hand domain Pkinase PF00069.25 EGR31007.1 - 6.5e-48 163.4 0.0 1.9e-47 161.9 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31007.1 - 4.4e-20 72.1 0.0 7.2e-19 68.1 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 EGR31007.1 - 0.013 15.1 0.1 0.013 15.1 0.1 1.8 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 UCH PF00443.29 EGR31008.1 - 6e-37 127.5 20.2 6e-37 127.5 20.2 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR31008.1 - 6.3e-08 32.6 19.2 6.3e-08 32.6 19.2 2.3 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase TetR_C_2 PF08361.11 EGR31008.1 - 0.025 14.7 0.1 0.025 14.7 0.1 2.9 3 0 0 3 3 3 0 MAATS-type transcriptional repressor, C-terminal region Myb_DNA-binding PF00249.31 EGR31009.1 - 2.5e-10 40.4 3.2 1.8e-08 34.4 0.4 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGR31009.1 - 2e-06 28.0 0.4 2e-06 28.0 0.4 3.1 3 1 0 3 3 3 1 Myb-like DNA-binding domain ZZ PF00569.17 EGR31009.1 - 0.0025 17.6 5.3 0.0046 16.8 5.3 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type zf-B_box PF00643.24 EGR31009.1 - 0.18 12.0 4.0 0.36 11.0 4.0 1.5 1 0 0 1 1 1 0 B-box zinc finger Sgf11 PF08209.11 EGR31009.1 - 0.21 11.2 0.3 0.43 10.2 0.3 1.5 1 0 0 1 1 1 0 Sgf11 (transcriptional regulation protein) UPF0167 PF03691.14 EGR31009.1 - 4.2 7.1 11.3 0.62 9.8 6.7 2.2 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0167) Cript PF10235.9 EGR31009.1 - 6.1 7.5 12.8 0.73 10.4 6.3 2.5 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT ANAPC4_WD40 PF12894.7 EGR31010.1 - 2.5e-06 27.7 0.2 5.2e-05 23.5 0.1 2.7 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGR31010.1 - 5.7e-05 23.8 0.2 0.0048 17.7 0.0 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat LRR_6 PF13516.6 EGR31010.1 - 0.0014 18.5 4.3 3.1 8.1 0.2 5.1 5 1 0 5 5 5 1 Leucine Rich repeat Telomere_reg-2 PF10193.9 EGR31011.1 - 7.7e-18 64.9 0.5 1.9e-17 63.7 0.0 1.9 2 0 0 2 2 2 1 Telomere length regulation protein Phage_FRD3 PF05798.11 EGR31011.1 - 0.053 13.8 0.4 0.12 12.6 0.4 1.7 1 0 0 1 1 1 0 Bacteriophage FRD3 protein CAS_C PF12026.8 EGR31011.1 - 0.1 12.7 5.1 0.15 12.1 5.1 1.3 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain Tristanin_u2 PF16638.5 EGR31011.1 - 0.11 13.4 3.6 0.22 12.4 3.6 1.5 1 0 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers Vfa1 PF08432.10 EGR31011.1 - 1.6 9.0 13.3 0.83 10.0 8.9 2.0 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF441 PF04284.13 EGR31012.1 - 0.092 12.8 4.0 0.24 11.4 1.0 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF441) Adaptin_N PF01602.20 EGR31014.1 - 3.2e-96 323.0 19.8 5.1e-96 322.3 19.8 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGR31014.1 - 3.8e-44 150.6 17.8 5.2e-42 143.6 0.4 4.3 3 2 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGR31014.1 - 4.6e-10 39.7 0.0 4.4e-05 23.8 0.0 3.3 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.22 EGR31014.1 - 4.2e-06 26.5 0.0 0.3 11.5 0.0 4.2 4 0 0 4 4 4 2 HEAT repeat RIX1 PF08167.12 EGR31014.1 - 0.00013 21.7 1.0 0.95 9.2 0.1 3.7 2 1 0 2 2 2 2 rRNA processing/ribosome biogenesis FANCI_S2 PF14676.6 EGR31014.1 - 0.00059 20.2 1.5 0.011 16.0 0.1 3.2 2 1 0 2 2 2 1 FANCI solenoid 2 UPF0560 PF10577.9 EGR31014.1 - 0.00094 17.8 6.6 0.00094 17.8 6.6 1.7 2 0 0 2 2 2 1 Uncharacterised protein family UPF0560 RTP1_C1 PF10363.9 EGR31014.1 - 0.007 16.5 0.5 0.068 13.3 0.1 3.1 2 1 0 2 2 2 1 Required for nuclear transport of RNA pol II C-terminus 1 Pkinase PF00069.25 EGR31015.1 - 5.7e-31 107.9 4.3 3.7e-24 85.5 0.0 2.9 1 1 2 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31015.1 - 1.1e-06 28.2 2.6 0.00038 19.8 0.0 3.5 3 1 0 3 3 3 2 Protein tyrosine kinase zf-CCCH PF00642.24 EGR31016.1 - 1.5e-07 31.1 17.3 0.00032 20.5 6.2 2.4 2 1 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_23 PF13476.6 EGR31016.1 - 0.00024 21.7 9.0 0.00039 21.0 9.0 1.3 1 0 0 1 1 1 1 AAA domain TPPII_N PF12583.8 EGR31016.1 - 0.063 13.9 1.9 0.22 12.1 0.2 2.3 2 0 0 2 2 2 0 Tripeptidyl peptidase II N terminal PC_rep PF01851.22 EGR31016.1 - 0.17 12.4 0.0 0.38 11.3 0.0 1.6 1 0 0 1 1 1 0 Proteasome/cyclosome repeat HrpJ PF07201.11 EGR31016.1 - 0.56 10.5 9.2 1.4e+02 2.7 7.4 2.3 1 1 0 1 1 1 0 HrpJ-like domain zf_CCCH_4 PF18345.1 EGR31016.1 - 3.1 8.0 16.0 6.9 6.9 6.3 2.5 2 0 0 2 2 2 0 Zinc finger domain Fis1_TPR_C PF14853.6 EGR31016.1 - 5.8 7.1 9.0 0.088 12.9 1.7 1.8 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Pkinase PF00069.25 EGR31017.1 - 9.7e-61 205.4 0.0 3.2e-60 203.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31017.1 - 4.1e-35 121.3 0.0 4.7e-25 88.4 0.2 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase PH_3 PF14593.6 EGR31017.1 - 1.1e-16 60.8 1.8 4.9e-16 58.7 0.7 2.4 2 0 0 2 2 2 1 PH domain Kinase-like PF14531.6 EGR31017.1 - 1.7e-06 27.5 0.0 0.057 12.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EGR31017.1 - 4.1e-06 26.9 0.0 2.1e-05 24.6 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGR31017.1 - 6.1e-05 22.1 0.5 0.00027 20.0 0.4 1.9 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EGR31017.1 - 0.0012 18.2 0.0 0.0041 16.5 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR31017.1 - 0.0034 16.2 0.0 0.0054 15.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EGR31017.1 - 0.0036 16.9 2.2 0.0096 15.5 0.0 2.4 3 0 0 3 3 3 1 RIO1 family FTA2 PF13095.6 EGR31017.1 - 0.0061 16.2 0.6 1.1 8.8 0.0 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Choline_kinase PF01633.20 EGR31017.1 - 0.012 15.2 2.1 0.016 14.8 0.6 1.8 1 1 1 2 2 2 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 EGR31017.1 - 0.036 13.6 0.1 0.086 12.3 0.1 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Seadorna_VP7 PF07387.11 EGR31017.1 - 0.05 12.7 3.1 0.14 11.2 3.1 1.7 1 1 0 1 1 1 0 Seadornavirus VP7 APH_6_hur PF04655.14 EGR31017.1 - 0.11 11.9 0.0 0.31 10.4 0.0 1.7 1 1 1 2 2 2 0 Aminoglycoside/hydroxyurea antibiotic resistance kinase Peptidase_S11 PF00768.20 EGR31018.1 - 3.9e-37 128.0 0.1 3.9e-37 128.0 0.1 4.2 2 1 1 3 3 3 1 D-alanyl-D-alanine carboxypeptidase Corona_7 PF02398.16 EGR31018.1 - 0.14 12.7 0.0 0.3 11.7 0.0 1.4 1 0 0 1 1 1 0 Coronavirus protein 7 CRAL_TRIO PF00650.20 EGR31019.1 - 7.3e-31 107.0 0.9 7.3e-31 107.0 0.9 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain KIAA1430 PF13879.6 EGR31019.1 - 3.8e-16 59.7 8.3 3.8e-16 59.7 8.3 2.8 3 0 0 3 3 3 1 KIAA1430 homologue CRAL_TRIO_2 PF13716.6 EGR31019.1 - 1.9e-08 34.5 0.6 1.9e-08 34.5 0.6 2.3 3 0 0 3 3 3 1 Divergent CRAL/TRIO domain DUF1908 PF08926.11 EGR31020.1 - 0.006 15.7 3.2 0.0071 15.5 3.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1908) CBAH PF02275.18 EGR31020.1 - 0.053 13.2 0.7 0.065 12.9 0.7 1.2 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family Sec34 PF04136.15 EGR31020.1 - 0.34 10.8 7.1 0.17 11.8 1.6 2.1 1 1 1 2 2 2 0 Sec34-like family DUF1281 PF06924.11 EGR31021.1 - 0.19 11.3 3.0 11 5.5 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1281) Tyr_Deacylase PF02580.16 EGR31022.1 - 9.7e-36 123.4 0.0 1.5e-35 122.9 0.0 1.2 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase CH_2 PF06294.11 EGR31024.1 - 1.7e-34 117.8 1.4 2.1e-34 117.5 0.2 1.8 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 EGR31024.1 - 3.1e-16 59.0 0.0 1.6e-15 56.7 0.0 2.1 1 1 1 2 2 2 1 CAMSAP CH domain CH PF00307.31 EGR31024.1 - 0.00016 21.8 1.0 0.0012 19.0 0.1 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain DUF641 PF04859.12 EGR31024.1 - 0.00064 20.1 1.7 0.0014 19.0 1.7 1.5 1 0 0 1 1 1 1 Plant protein of unknown function (DUF641) Prefoldin_2 PF01920.20 EGR31024.1 - 0.017 15.1 8.1 0.25 11.3 4.5 2.5 2 0 0 2 2 2 0 Prefoldin subunit PKcGMP_CC PF16808.5 EGR31024.1 - 0.019 14.8 6.8 0.26 11.1 1.5 3.0 2 1 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Atg14 PF10186.9 EGR31024.1 - 0.055 12.6 6.7 0.091 11.8 6.7 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 SPATA24 PF15175.6 EGR31024.1 - 0.057 13.3 2.1 0.057 13.3 2.1 2.7 2 1 1 3 3 3 0 Spermatogenesis-associated protein 24 BLOC1_2 PF10046.9 EGR31024.1 - 0.076 13.3 4.6 0.18 12.1 4.6 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 EGR31024.1 - 0.27 11.4 7.9 0.32 11.2 6.7 1.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family DUF16 PF01519.16 EGR31024.1 - 1.7 9.2 9.7 7.4 7.1 9.7 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 Syntaxin-6_N PF09177.11 EGR31024.1 - 2.9 8.5 6.2 14 6.3 6.2 2.2 1 1 0 1 1 1 0 Syntaxin 6, N-terminal HR1 PF02185.16 EGR31024.1 - 2.9 8.1 9.7 0.87 9.8 4.1 2.6 2 1 1 3 3 3 0 Hr1 repeat XLF PF09302.11 EGR31024.1 - 3.5 7.8 9.8 3.3 7.8 3.9 2.7 1 1 2 3 3 3 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component FAM76 PF16046.5 EGR31024.1 - 6.7 6.0 7.4 6.2 6.1 6.3 1.4 1 1 0 1 1 1 0 FAM76 protein zf-ANAPC11 PF12861.7 EGR31025.1 - 1.4e-05 25.0 9.2 5.9e-05 23.0 9.2 2.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-TRAF PF02176.18 EGR31025.1 - 4.6e-05 24.0 3.9 4.6e-05 24.0 3.9 2.9 2 0 0 2 2 2 1 TRAF-type zinc finger Sina PF03145.16 EGR31025.1 - 7.6e-05 22.7 2.3 7.6e-05 22.7 2.3 3.2 5 0 0 5 5 5 1 Seven in absentia protein family zf-C3HC4_2 PF13923.6 EGR31025.1 - 0.0056 16.5 20.0 0.0056 16.5 20.0 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGR31025.1 - 0.01 16.1 20.7 0.01 16.1 20.7 4.0 4 1 0 4 4 4 0 Ring finger domain zf-rbx1 PF12678.7 EGR31025.1 - 0.012 15.9 13.5 0.012 15.9 13.5 3.0 3 0 0 3 3 3 0 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGR31025.1 - 0.017 15.0 21.0 0.017 15.0 21.0 3.2 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) Inhibitor_I67 PF11405.8 EGR31025.1 - 0.59 10.4 9.6 0.6 10.4 7.2 2.4 1 1 1 2 2 2 0 Bromelain inhibitor VI GBP PF02263.19 EGR31026.1 - 2.7e-62 210.4 0.9 2.7e-62 210.4 0.9 1.9 2 1 0 2 2 2 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 EGR31026.1 - 1.8e-08 34.1 13.9 1.8e-08 34.1 13.9 2.0 2 1 0 2 2 2 1 Guanylate-binding protein, C-terminal domain MMR_HSR1 PF01926.23 EGR31026.1 - 0.033 14.3 1.2 0.078 13.1 0.1 2.4 2 1 0 2 2 2 0 50S ribosome-binding GTPase POTRA PF07244.15 EGR31026.1 - 0.052 14.1 5.8 4.4 7.9 1.2 3.1 2 1 0 2 2 2 0 Surface antigen variable number repeat PTPS PF01242.19 EGR31026.1 - 0.14 12.2 0.4 0.3 11.0 0.4 1.8 1 0 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase Pkinase PF00069.25 EGR31028.1 - 2.8e-71 240.0 0.6 3.4e-71 239.7 0.6 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31028.1 - 7.6e-34 117.2 0.1 9.8e-34 116.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31028.1 - 1.6e-07 30.9 0.2 6.3e-06 25.7 0.2 2.2 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR31028.1 - 5.4e-06 25.9 0.3 7.7e-06 25.4 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGR31028.1 - 1.9e-05 23.8 1.8 3.1e-05 23.1 1.8 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EGR31028.1 - 5.3e-05 23.0 1.0 0.0075 15.9 0.1 2.2 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 DUF1642 PF07852.11 EGR31028.1 - 0.032 14.8 0.6 0.055 14.1 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1642) Phage_int_SAM_4 PF13495.6 EGR31028.1 - 0.071 13.6 0.6 0.16 12.5 0.1 1.8 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain ORC3_N PF07034.11 EGR31029.1 - 0.0033 16.6 5.6 0.0052 15.9 5.6 1.4 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ADK PF00406.22 EGR31030.1 - 7.3e-17 61.9 1.9 3.8e-15 56.3 0.4 2.4 2 0 0 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 EGR31030.1 - 8.8e-08 32.7 0.0 4.9e-05 23.8 0.0 2.7 2 1 0 2 2 2 2 AAA domain DUF5586 PF17824.1 EGR31030.1 - 5.3e-05 22.5 0.4 0.0001 21.6 0.4 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5586) DUF5582 PF17819.1 EGR31030.1 - 0.0015 19.0 1.2 0.0015 19.0 1.2 2.8 3 0 0 3 3 3 1 Family of unknown function (DUF5582) DUF4570 PF15134.6 EGR31030.1 - 0.0062 16.5 0.2 0.14 12.2 0.0 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4570) Holin_BhlA PF10960.8 EGR31030.1 - 0.0086 16.0 0.6 0.0086 16.0 0.6 3.0 3 1 0 3 3 3 1 BhlA holin family Dpy-30 PF05186.13 EGR31030.1 - 0.052 13.3 0.1 0.1 12.3 0.1 1.5 1 0 0 1 1 1 0 Dpy-30 motif RIIa PF02197.17 EGR31030.1 - 0.083 12.6 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Helicase_C PF00271.31 EGR31032.1 - 2.1e-25 89.2 2.9 2.1e-25 89.2 2.9 2.4 2 1 0 2 2 2 1 Helicase conserved C-terminal domain Secretin_N_2 PF07655.13 EGR31032.1 - 1.7 9.2 15.3 5.2 7.7 15.3 1.9 1 0 0 1 1 1 0 Secretin N-terminal domain Presenilin PF01080.17 EGR31032.1 - 2.9 6.5 8.3 4.1 6.1 8.3 1.3 1 0 0 1 1 1 0 Presenilin Dapper PF15268.6 EGR31032.1 - 7.3 5.3 11.1 9.3 5.0 11.1 1.0 1 0 0 1 1 1 0 Dapper GTP_EFTU PF00009.27 EGR31034.1 - 3.4e-06 26.7 6.2 0.0041 16.7 6.5 3.0 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGR31034.1 - 7e-06 26.1 2.6 0.038 14.1 0.0 3.3 2 2 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EGR31034.1 - 5.9e-05 22.7 1.7 0.053 13.1 0.1 2.9 2 1 1 3 3 3 2 Ferrous iron transport protein B Roc PF08477.13 EGR31034.1 - 0.0061 16.8 8.7 0.36 11.0 0.0 4.0 3 1 1 4 4 4 2 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 EGR31034.1 - 0.015 14.3 1.3 0.082 11.9 0.0 2.4 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 EGR31034.1 - 0.062 13.2 8.3 0.38 10.6 0.1 3.2 2 1 1 3 3 3 0 RsgA GTPase AAA_18 PF13238.6 EGR31034.1 - 0.098 13.2 0.4 0.098 13.2 0.4 3.0 2 2 0 2 2 2 0 AAA domain Svf1_C PF17187.4 EGR31034.1 - 1.3 8.9 10.5 0.14 12.0 5.0 2.1 2 1 0 2 2 2 0 Svf1-like C-terminal lipocalin-like domain TPR_12 PF13424.6 EGR31035.1 - 8.8e-29 99.6 8.9 1.6e-09 37.9 0.1 5.0 2 1 4 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGR31035.1 - 2.8e-20 70.7 5.2 0.031 14.4 0.1 6.6 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 EGR31035.1 - 1.2e-13 50.2 17.5 0.00072 19.3 0.1 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGR31035.1 - 4.9e-08 33.4 4.9 0.12 12.9 0.1 5.8 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGR31035.1 - 7.9e-08 31.9 23.3 0.011 15.8 0.1 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGR31035.1 - 3.9e-07 29.6 4.3 0.21 11.7 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGR31035.1 - 3.4e-06 26.7 5.4 0.6 10.1 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGR31035.1 - 0.00013 22.4 7.1 9.5 7.1 0.1 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGR31035.1 - 0.0015 18.8 6.3 49 4.6 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR31035.1 - 0.0023 18.1 16.3 0.57 10.4 0.4 5.4 3 1 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 EGR31035.1 - 0.056 13.5 22.0 0.76 9.9 2.0 5.5 5 1 0 6 6 5 0 MIT (microtubule interacting and transport) domain TPR_16 PF13432.6 EGR31035.1 - 0.1 13.3 0.0 16 6.2 0.0 3.7 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGR31035.1 - 0.84 9.4 13.9 6.4 6.6 0.2 5.8 6 0 0 6 6 6 0 TPR repeat TPR_20 PF14561.6 EGR31035.1 - 1.8 9.0 16.7 8.1 6.9 0.0 6.1 5 2 2 7 7 7 0 Tetratricopeptide repeat DNase_II PF03265.15 EGR31038.1 - 1.8e-70 237.8 11.1 1.8e-70 237.8 11.1 2.5 3 0 0 3 3 3 1 Deoxyribonuclease II Pkinase PF00069.25 EGR31038.1 - 1.3e-61 208.3 0.1 2.7e-61 207.3 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31038.1 - 2.4e-29 102.4 0.1 3.5e-29 101.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31038.1 - 2.4e-06 27.1 0.0 0.0001 21.7 0.0 2.3 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EGR31038.1 - 0.0098 15.3 0.4 0.03 13.7 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR31038.1 - 0.012 14.4 0.1 3.1 6.5 0.0 2.2 1 1 1 2 2 2 0 Fungal protein kinase TusA PF01206.17 EGR31038.1 - 0.078 12.8 0.0 0.31 10.9 0.0 2.0 1 0 0 1 1 1 0 Sulfurtransferase TusA WD40 PF00400.32 EGR31039.1 - 7.3e-27 93.1 11.4 0.0001 23.0 0.2 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR31039.1 - 1e-10 41.7 0.1 0.0083 16.4 0.0 5.3 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain ADIP PF11559.8 EGR31039.1 - 0.0029 17.7 15.1 0.0029 17.7 15.1 5.5 3 1 0 4 4 4 1 Afadin- and alpha -actinin-Binding DUF2316 PF10078.9 EGR31039.1 - 0.3 11.3 7.7 5.5 7.3 0.4 3.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) CENP-B_dimeris PF09026.10 EGR31039.1 - 0.45 10.9 3.3 0.61 10.5 0.2 2.7 3 0 0 3 3 3 0 Centromere protein B dimerisation domain ApoO PF09769.9 EGR31039.1 - 1.1 9.2 3.0 27 4.7 0.2 3.0 2 1 0 2 2 2 0 Apolipoprotein O PET PF06297.14 EGR31039.1 - 5.9 7.3 8.1 0.66 10.3 0.9 3.0 2 0 0 2 2 2 0 PET Domain PUB PF09409.10 EGR31040.1 - 9.2e-19 67.2 2.8 1.5e-18 66.5 1.0 2.3 2 0 0 2 2 2 1 PUB domain UBA PF00627.31 EGR31040.1 - 2.1e-08 33.9 0.0 0.0098 15.8 0.0 2.9 2 0 0 2 2 2 2 UBA/TS-N domain TB2_DP1_HVA22 PF03134.19 EGR31042.1 - 2.2e-16 59.5 7.1 3.3e-16 59.0 7.1 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family MORN PF02493.20 EGR31044.1 - 1.9e-39 131.2 95.8 3.6e-07 29.7 1.9 15.5 16 0 0 16 16 16 11 MORN repeat Pkinase PF00069.25 EGR31045.1 - 2.8e-60 203.9 1.0 2.8e-60 203.9 1.0 2.6 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31045.1 - 8e-35 120.4 0.2 1.7e-34 119.3 0.2 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGR31046.1 - 6e-69 232.3 0.0 7.1e-69 232.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31046.1 - 1.8e-39 135.6 0.0 2.3e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31046.1 - 2.5e-05 23.7 0.0 5e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR31046.1 - 0.014 14.2 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EGR31046.1 - 0.094 12.2 0.0 0.14 11.6 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL HEPN_Apea PF18739.1 EGR31047.1 - 0.25 11.8 3.6 0.17 12.3 1.0 2.1 2 0 0 2 2 2 0 Apea-like HEPN Gpi16 PF04113.14 EGR31048.1 - 9e-15 54.1 0.5 1.1e-14 53.8 0.5 1.1 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component EF-hand_7 PF13499.6 EGR31049.1 - 6.5e-20 71.4 11.9 5e-12 46.1 3.5 3.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR31049.1 - 8.4e-20 68.8 10.8 2.3e-07 29.8 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGR31049.1 - 5.1e-17 60.3 10.3 3.2e-06 26.6 0.1 3.7 4 0 0 4 4 3 3 EF-hand domain EF-hand_5 PF13202.6 EGR31049.1 - 1.4e-14 52.8 10.9 1.8e-05 24.0 0.1 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EGR31049.1 - 1.8e-14 53.3 11.3 2.7e-07 30.3 1.8 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EGR31049.1 - 0.0004 20.3 7.9 0.001 19.0 2.3 2.2 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EGR31049.1 - 0.0017 18.6 0.6 0.12 12.7 0.2 2.7 3 1 0 3 3 3 1 EF-hand domain SPARC_Ca_bdg PF10591.9 EGR31049.1 - 0.003 17.9 3.8 0.0057 17.0 2.0 1.9 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 EGR31049.1 - 0.042 13.8 1.3 1.6 8.6 0.0 3.0 1 1 3 4 4 4 0 Caleosin related protein EF-hand_11 PF08976.11 EGR31049.1 - 0.052 14.4 0.8 0.26 12.2 0.2 2.1 1 1 1 2 2 2 0 EF-hand domain ABC_trans_N PF14510.6 EGR31049.1 - 0.08 13.6 0.4 0.79 10.4 0.0 2.2 1 1 1 2 2 2 0 ABC-transporter N-terminal SUB1_ProdP9 PF18213.1 EGR31049.1 - 0.083 12.7 0.7 0.083 12.7 0.7 2.3 1 1 1 2 2 2 0 SUB1 protease Prodomain ProdP9 FGAR-AT_linker PF18072.1 EGR31049.1 - 0.22 12.1 1.6 4.8 7.8 0.0 3.0 3 1 1 4 4 4 0 Formylglycinamide ribonucleotide amidotransferase linker domain DUF848 PF05852.11 EGR31049.1 - 0.43 10.7 3.5 5.6 7.1 0.1 2.2 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) MSA-2c PF12238.8 EGR31049.1 - 0.91 9.5 5.1 1.2 9.1 5.1 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Herp-Cyclin PF09241.10 EGR31050.1 - 0.055 14.1 0.2 7 7.3 0.0 3.0 2 1 1 3 3 3 0 Herpesviridae viral cyclin DUF1126 PF06565.12 EGR31050.1 - 1.9 8.4 7.0 0.4 10.5 1.9 2.5 2 0 0 2 2 2 0 DUF1126 PH-like domain MFS_1 PF07690.16 EGR31051.1 - 1.3e-19 70.4 8.7 1.3e-19 70.4 8.7 2.2 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EGR31051.1 - 4.5e-07 29.7 19.9 4.5e-07 29.7 19.9 4.5 1 1 2 4 4 4 2 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 EGR31051.1 - 0.00022 20.2 29.0 0.00069 18.6 8.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter Pkinase PF00069.25 EGR31052.1 - 2.6e-59 200.7 18.2 2.2e-39 135.4 1.1 4.0 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31052.1 - 2.3e-29 102.5 0.6 1.9e-21 76.5 0.3 2.8 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 EGR31052.1 - 0.0079 16.9 0.7 0.019 15.7 0.7 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain AAA_12 PF13087.6 EGR31053.1 - 4.4e-61 206.0 0.1 2.9e-60 203.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EGR31053.1 - 1.9e-47 162.2 7.0 2.2e-25 89.9 0.1 3.3 2 1 1 3 3 3 2 AAA domain UPF1_Zn_bind PF09416.10 EGR31053.1 - 4.1e-35 121.0 2.4 5.8e-35 120.5 1.2 2.0 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) DUF5599 PF18141.1 EGR31053.1 - 2.3e-16 59.8 0.1 5.3e-16 58.6 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) AAA_19 PF13245.6 EGR31053.1 - 4.9e-13 49.6 0.3 2.2e-12 47.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGR31053.1 - 3.8e-12 46.3 0.0 1.6e-11 44.3 0.0 1.9 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EGR31053.1 - 5.2e-08 33.1 5.7 5.3e-08 33.0 0.0 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGR31053.1 - 9.4e-05 22.3 0.0 0.0002 21.2 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Viral_helicase1 PF01443.18 EGR31053.1 - 0.0016 18.2 0.0 0.83 9.3 0.0 3.1 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 EGR31053.1 - 0.0089 16.3 0.3 0.075 13.3 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EGR31053.1 - 0.038 14.4 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EGR31053.1 - 0.042 13.3 0.0 0.11 11.9 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein UvrD_C_2 PF13538.6 EGR31053.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_16 PF13191.6 EGR31053.1 - 0.098 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 EGR31053.1 - 0.18 11.4 0.0 0.37 10.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_pol_L_2 PF13656.6 EGR31054.1 - 2.5e-22 78.4 0.5 3.7e-22 77.9 0.5 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EGR31054.1 - 0.0088 15.5 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Gar1 PF04410.14 EGR31055.1 - 1.1e-32 112.9 0.0 1.5e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region adh_short PF00106.25 EGR31057.1 - 1.1e-14 54.3 0.0 1.5e-14 53.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGR31057.1 - 5.4e-12 45.8 0.0 9.3e-12 45.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MORN PF02493.20 EGR31058.1 - 1.1e-35 119.4 43.2 2.7e-07 30.1 2.0 6.7 6 0 0 6 6 6 6 MORN repeat KH_8 PF17903.1 EGR31059.1 - 1.3e-30 105.3 2.1 2e-30 104.7 0.0 2.4 2 0 0 2 2 2 1 Krr1 KH1 domain KH_1 PF00013.29 EGR31059.1 - 0.0013 18.5 0.0 0.0086 15.9 0.0 2.3 1 1 1 2 2 2 1 KH domain KH_4 PF13083.6 EGR31059.1 - 0.032 14.1 0.0 0.11 12.4 0.0 1.9 1 0 0 1 1 1 0 KH domain IF-2B PF01008.17 EGR31060.1 - 7.6e-45 153.3 0.7 9.9e-45 152.9 0.7 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family Globin PF00042.22 EGR31060.1 - 0.019 15.5 0.1 0.06 13.9 0.1 1.8 1 1 0 1 1 1 0 Globin Methyltransf_14 PF08484.11 EGR31060.1 - 0.029 14.2 0.2 0.047 13.5 0.2 1.4 1 0 0 1 1 1 0 C-methyltransferase C-terminal domain Plant_NMP1 PF06694.11 EGR31060.1 - 0.034 13.2 0.8 0.045 12.9 0.8 1.2 1 0 0 1 1 1 0 Plant nuclear matrix protein 1 (NMP1) Neural_ProG_Cyt PF06567.11 EGR31060.1 - 0.05 13.8 0.7 0.12 12.5 0.7 1.6 1 0 0 1 1 1 0 Neural chondroitin sulphate proteoglycan cytoplasmic domain Plk4_PB2 PF18409.1 EGR31060.1 - 0.091 13.5 2.5 4 8.2 0.5 2.4 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 Z1 PF10593.9 EGR31060.1 - 0.098 12.1 3.7 0.17 11.4 3.7 1.4 1 0 0 1 1 1 0 Z1 domain DnaJ PF00226.31 EGR31061.1 - 2.2e-18 66.1 2.5 8.7e-18 64.2 2.5 2.1 1 0 0 1 1 1 1 DnaJ domain Baculo_PEP_N PF04512.12 EGR31061.1 - 0.065 13.5 0.0 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, N terminus YchF-GTPase_C PF06071.13 EGR31062.1 - 1.2e-33 115.2 2.3 3.1e-33 113.8 2.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EGR31062.1 - 5.6e-18 65.1 0.0 1.3e-17 63.9 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGR31062.1 - 0.00014 21.4 0.0 0.00039 20.0 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF1738 PF08401.11 EGR31062.1 - 0.15 12.2 1.2 0.28 11.3 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1738) Pkinase PF00069.25 EGR31064.1 - 1.1e-45 156.0 0.0 1.3e-45 155.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31064.1 - 6.8e-24 84.5 0.0 8.8e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31064.1 - 0.00018 21.0 0.0 0.00021 20.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGR31064.1 - 0.082 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pox_MCEL PF03291.16 EGR31065.1 - 3.1e-49 167.9 23.2 3.1e-49 167.9 23.2 1.7 1 1 1 2 2 2 1 mRNA capping enzyme Methyltransf_25 PF13649.6 EGR31065.1 - 4.3e-09 37.0 0.3 1.9e-07 31.7 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGR31065.1 - 6.6e-09 36.4 2.5 7.9e-07 29.7 0.0 3.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGR31065.1 - 2.5e-06 27.4 0.6 5.2e-06 26.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGR31065.1 - 4.2e-06 27.3 0.2 0.016 15.8 0.0 3.3 4 0 0 4 4 4 2 Methyltransferase domain Methyltransf_31 PF13847.6 EGR31065.1 - 5.6e-05 23.0 1.2 5.6e-05 23.0 1.2 2.9 2 1 0 2 2 2 1 Methyltransferase domain TPMT PF05724.11 EGR31065.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Polo_box_3 PF18544.1 EGR31065.1 - 0.11 13.2 2.3 0.26 12.0 0.1 2.8 2 0 0 2 2 2 0 Polo box domain DUF4834 PF16118.5 EGR31065.1 - 4.1 8.4 12.2 3 8.9 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF3537 PF12056.8 EGR31065.1 - 9 5.0 6.4 2.4 6.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3537) Aminotran_5 PF00266.19 EGR31066.1 - 1.3e-28 100.0 0.1 2.2e-25 89.4 0.1 2.4 2 1 0 2 2 2 2 Aminotransferase class-V Pyridoxal_deC PF00282.19 EGR31066.1 - 8.8e-05 21.4 0.4 0.00014 20.7 0.0 1.6 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 EGR31066.1 - 0.00066 19.1 0.0 0.0013 18.1 0.0 1.4 1 1 0 1 1 1 1 Beta-eliminating lyase Imm7 PF15585.6 EGR31066.1 - 0.12 12.6 0.1 0.4 11.0 0.1 1.9 2 0 0 2 2 2 0 Immunity protein 7 Citrate_synt PF00285.21 EGR31067.1 - 9.6e-82 274.9 0.0 1e-81 274.8 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF4471 PF14740.6 EGR31068.1 - 7.5e-44 150.2 1.2 7.5e-44 150.2 1.2 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4471) DUF4470 PF14737.6 EGR31068.1 - 1.7e-22 79.4 2.5 2.1e-22 79.2 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4470) CENP-F_leu_zip PF10473.9 EGR31070.1 - 3.5e-05 23.8 14.2 0.032 14.3 3.7 2.1 1 1 1 2 2 2 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4164 PF13747.6 EGR31070.1 - 0.00053 20.2 10.9 0.026 14.8 4.1 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4164) Leu_zip PF15294.6 EGR31070.1 - 0.0042 16.7 9.9 0.0053 16.3 9.9 1.1 1 0 0 1 1 1 1 Leucine zipper Phlebovirus_NSM PF07246.11 EGR31070.1 - 0.0082 15.6 0.6 0.0082 15.6 0.6 1.9 1 1 1 2 2 2 1 Phlebovirus nonstructural protein NS-M UPF0242 PF06785.11 EGR31070.1 - 0.0093 16.1 10.7 0.013 15.6 10.7 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Jnk-SapK_ap_N PF09744.9 EGR31070.1 - 0.012 15.8 14.5 0.18 12.0 7.4 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Nsp1_C PF05064.13 EGR31070.1 - 0.014 15.2 9.9 0.11 12.3 9.9 2.0 1 1 0 1 1 1 0 Nsp1-like C-terminal region CCDC144C PF14915.6 EGR31070.1 - 0.016 14.3 15.5 0.14 11.3 15.7 1.8 1 1 0 1 1 1 0 CCDC144C protein coiled-coil region FRG1 PF06229.12 EGR31070.1 - 0.017 14.9 1.9 0.02 14.6 1.9 1.1 1 0 0 1 1 1 0 FRG1-like domain Tektin PF03148.14 EGR31070.1 - 0.017 13.9 12.0 0.48 9.1 12.2 2.0 1 1 0 1 1 1 0 Tektin family Rootletin PF15035.6 EGR31070.1 - 0.027 14.5 3.0 0.027 14.5 3.0 2.0 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion GAS PF13851.6 EGR31070.1 - 0.058 12.7 15.7 0.79 9.0 15.3 2.2 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 EGR31070.1 - 0.062 12.2 11.1 0.088 11.7 11.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein SKA2 PF16740.5 EGR31070.1 - 0.066 13.0 10.7 0.49 10.2 1.7 2.6 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 Syntaxin-6_N PF09177.11 EGR31070.1 - 0.085 13.4 6.9 0.22 12.1 0.7 2.1 1 1 1 2 2 2 0 Syntaxin 6, N-terminal LMBR1 PF04791.16 EGR31070.1 - 0.088 11.7 5.0 0.1 11.5 5.0 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein FlaC_arch PF05377.11 EGR31070.1 - 0.098 13.1 13.2 0.64 10.5 4.6 2.7 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) DASH_Dad2 PF08654.10 EGR31070.1 - 0.13 12.7 7.4 0.15 12.4 2.4 2.1 1 1 1 2 2 2 0 DASH complex subunit Dad2 Baculo_PEP_C PF04513.12 EGR31070.1 - 0.14 12.1 8.2 0.99 9.4 8.2 2.0 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ZapB PF06005.12 EGR31070.1 - 0.16 12.4 18.1 0.11 12.9 1.7 2.6 2 1 0 2 2 2 0 Cell division protein ZapB Tup_N PF08581.10 EGR31070.1 - 0.18 12.1 12.1 1.5 9.2 7.2 2.2 1 1 1 2 2 2 0 Tup N-terminal Fib_alpha PF08702.10 EGR31070.1 - 0.18 12.0 8.7 0.27 11.4 8.7 1.3 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family ABC_tran_CTD PF16326.5 EGR31070.1 - 0.21 11.9 11.9 0.75 10.1 0.4 3.1 2 1 1 3 3 3 0 ABC transporter C-terminal domain HIP1_clath_bdg PF16515.5 EGR31070.1 - 0.22 12.1 12.4 1 10.0 9.6 2.0 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 SAM_KSR1 PF13543.6 EGR31070.1 - 0.24 11.6 6.6 0.37 10.9 1.8 2.5 2 1 1 3 3 3 0 SAM like domain present in kinase suppressor RAS 1 Helo_like_N PF17111.5 EGR31070.1 - 0.26 10.6 7.8 0.53 9.6 0.4 2.1 2 0 0 2 2 2 0 Fungal N-terminal domain of STAND proteins FapA PF03961.13 EGR31070.1 - 0.47 9.0 14.1 1.6 7.2 14.1 1.7 1 1 0 1 1 1 0 Flagellar Assembly Protein A APG6_N PF17675.1 EGR31070.1 - 0.5 10.9 15.6 5 7.7 5.3 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region ATG16 PF08614.11 EGR31070.1 - 0.57 10.4 16.3 2.8 8.1 6.6 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Troponin PF00992.20 EGR31070.1 - 0.59 10.4 13.3 0.88 9.9 10.9 1.9 1 1 1 2 2 2 0 Troponin CENP-Q PF13094.6 EGR31070.1 - 0.67 10.1 14.1 4.1 7.6 1.4 2.2 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF2968 PF11180.8 EGR31070.1 - 0.81 9.3 13.2 2.3 7.8 13.3 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) DUF724 PF05266.14 EGR31070.1 - 0.89 9.3 10.4 3.9 7.3 2.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) DUF5320 PF17253.2 EGR31070.1 - 0.92 10.6 12.4 0.9 10.7 2.0 3.2 1 1 1 2 2 2 0 Family of unknown function (DUF5320) zf-C4H2 PF10146.9 EGR31070.1 - 0.97 9.7 13.4 20 5.4 8.6 2.0 1 1 1 2 2 2 0 Zinc finger-containing protein Siah-Interact_N PF09032.11 EGR31070.1 - 1 9.7 9.3 0.21 11.9 0.9 2.8 1 1 2 3 3 3 0 Siah interacting protein, N terminal JIP_LZII PF16471.5 EGR31070.1 - 1.1 9.5 12.8 0.58 10.4 0.4 3.4 1 1 3 4 4 4 0 JNK-interacting protein leucine zipper II Enkurin PF13864.6 EGR31070.1 - 1.3 9.6 11.4 2.2 8.8 11.4 1.5 1 1 0 1 1 1 0 Calmodulin-binding DUF1664 PF07889.12 EGR31070.1 - 1.3 9.1 7.9 3 7.9 2.8 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Prefoldin_2 PF01920.20 EGR31070.1 - 1.4 8.9 17.1 1.4 8.9 3.9 3.1 1 1 2 3 3 3 0 Prefoldin subunit DUF4140 PF13600.6 EGR31070.1 - 1.4 9.4 8.6 1.5e+02 2.9 8.6 2.4 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Snapin_Pallidin PF14712.6 EGR31070.1 - 1.5 9.3 15.3 4.3 7.8 1.3 2.2 1 1 1 2 2 2 0 Snapin/Pallidin Lipoprotein_20 PF13942.6 EGR31070.1 - 1.9 8.4 10.8 0.68 9.8 3.9 2.0 1 1 1 2 2 2 0 YfhG lipoprotein DUF1542 PF07564.11 EGR31070.1 - 2 8.6 11.0 2 8.5 3.5 2.4 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1542) DUF4407 PF14362.6 EGR31070.1 - 2.1 7.6 9.4 12 5.1 1.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Tho2 PF11262.8 EGR31070.1 - 3.1 6.9 11.4 10 5.2 11.3 1.8 1 1 0 1 1 1 0 Transcription factor/nuclear export subunit protein 2 Ly49 PF08391.10 EGR31070.1 - 3.2 8.1 9.0 1.6 9.1 6.4 1.7 1 1 1 2 2 2 0 Ly49-like protein, N-terminal region DUF16 PF01519.16 EGR31070.1 - 3.5 8.1 14.9 16 6.1 9.4 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 FAM76 PF16046.5 EGR31070.1 - 3.7 6.8 8.7 1.3 8.3 6.4 1.4 1 1 0 1 1 1 0 FAM76 protein DUF1192 PF06698.11 EGR31070.1 - 4.4 7.4 9.4 0.27 11.3 0.7 3.0 3 2 0 3 3 3 0 Protein of unknown function (DUF1192) Uso1_p115_C PF04871.13 EGR31070.1 - 4.6 7.6 13.4 1.1e+02 3.1 13.4 2.0 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spc24 PF08286.11 EGR31070.1 - 5.1 7.4 13.4 6.3 7.1 1.3 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 bZIP_1 PF00170.21 EGR31070.1 - 5.7 7.1 15.3 0.69 10.1 1.8 3.0 2 1 1 3 3 3 0 bZIP transcription factor YabA PF06156.13 EGR31070.1 - 6.3 7.5 11.1 2.3e+02 2.5 11.1 2.3 1 1 0 1 1 1 0 Initiation control protein YabA DUF3450 PF11932.8 EGR31070.1 - 6.6 6.0 14.0 5.2 6.3 5.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) XhlA PF10779.9 EGR31070.1 - 8.1 6.7 11.2 58 4.0 3.3 3.0 1 1 1 2 2 2 0 Haemolysin XhlA TMPIT PF07851.13 EGR31070.1 - 8.8 5.5 9.8 69 2.5 9.8 1.9 1 1 0 1 1 1 0 TMPIT-like protein Pkinase PF00069.25 EGR31071.1 - 2.6e-65 220.4 1.5 2.6e-65 220.4 1.5 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31071.1 - 2e-40 138.7 0.2 5e-40 137.4 0.2 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31071.1 - 1.5e-07 31.0 4.2 2.8e-07 30.2 0.0 3.2 2 1 1 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 EGR31071.1 - 0.00025 20.0 1.2 0.00025 20.0 1.2 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGR31071.1 - 0.0028 17.0 0.1 0.0065 15.9 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Rhabdo_matrix PF03397.14 EGR31072.1 - 0.099 12.4 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus matrix protein Ribosomal_S13_N PF08069.12 EGR31073.1 - 1.5e-27 95.4 0.8 2.4e-27 94.7 0.8 1.4 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EGR31073.1 - 6.7e-14 51.9 0.9 1e-13 51.3 0.9 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 ASH PF15780.5 EGR31074.1 - 6.2e-05 23.1 1.0 0.016 15.4 0.0 3.1 3 0 0 3 3 3 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 EGR31074.1 - 0.068 13.4 0.1 0.068 13.4 0.1 2.6 3 0 0 3 3 3 0 Transmembrane protein 131-like Tox-HNH-HHH PF15637.6 EGR31074.1 - 9 6.5 12.9 0.91 9.7 4.0 2.6 1 1 1 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif Ribosomal_S19e PF01090.19 EGR31076.1 - 3.1e-46 156.5 0.5 3.6e-46 156.3 0.5 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e PDE4_UCR PF18100.1 EGR31076.1 - 0.017 15.7 0.4 0.06 14.0 0.2 1.9 2 0 0 2 2 2 0 Phosphodiesterase 4 upstream conserved regions (UCR) Roc PF08477.13 EGR31077.1 - 3.3e-14 53.1 1.1 1.4e-13 51.1 1.1 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGR31077.1 - 2.5e-12 46.7 1.1 5.4e-12 45.6 1.1 1.6 1 1 0 1 1 1 1 Ras family Arf PF00025.21 EGR31077.1 - 0.0059 16.1 0.3 0.011 15.2 0.3 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_24 PF13479.6 EGR31077.1 - 0.027 14.2 0.2 0.038 13.7 0.2 1.4 1 1 0 1 1 1 0 AAA domain TBCC PF07986.12 EGR31078.1 - 6.6e-31 106.5 1.0 6.6e-31 106.5 1.0 2.4 2 2 1 3 3 3 1 Tubulin binding cofactor C CAP_C PF08603.11 EGR31078.1 - 0.0005 19.7 0.4 0.0005 19.7 0.4 2.2 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal DUF1778 PF08681.11 EGR31078.1 - 0.002 18.0 0.3 0.0049 16.8 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1778) PRP1_N PF06424.12 EGR31078.1 - 0.035 14.5 8.3 0.065 13.6 8.3 1.4 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Clathrin_lg_ch PF01086.17 EGR31078.1 - 0.18 11.8 11.7 0.45 10.5 11.6 1.6 1 1 0 1 1 1 0 Clathrin light chain MRP-S32 PF10210.9 EGR31078.1 - 1 9.9 7.7 2 9.0 7.7 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 Mito_carr PF00153.27 EGR31080.1 - 6.4e-38 128.6 0.6 4.4e-19 68.2 0.0 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF4499 PF14934.6 EGR31080.1 - 0.048 14.0 0.0 0.099 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4499) Mito_carr PF00153.27 EGR31081.1 - 1.4e-65 217.3 2.9 4.3e-24 84.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3764 PF12594.8 EGR31081.1 - 0.18 11.9 0.4 16 5.6 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3764) Spt4 PF06093.13 EGR31082.1 - 3.2 7.9 6.4 0.39 10.8 1.0 2.2 2 0 0 2 2 2 0 Spt4/RpoE2 zinc finger Histone PF00125.24 EGR31084.1 - 2.1e-15 57.2 0.0 3.3e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EGR31084.1 - 1.8e-13 49.9 0.3 3.8e-13 48.9 0.3 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EGR31084.1 - 0.056 13.7 0.0 0.074 13.3 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone EF-hand_7 PF13499.6 EGR31085.1 - 0.0067 16.9 0.3 0.38 11.3 0.1 1.9 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR31085.1 - 0.0086 15.6 0.5 0.15 11.7 0.0 2.9 3 0 0 3 3 3 1 EF hand EF-hand_10 PF14788.6 EGR31085.1 - 0.091 12.6 0.9 1.1 9.2 0.0 2.8 3 0 0 3 3 3 0 EF hand HMMR_N PF15905.5 EGR31087.1 - 0.00017 21.2 34.8 0.031 13.8 15.3 2.7 1 1 2 3 3 3 2 Hyaluronan mediated motility receptor N-terminal DUF1192 PF06698.11 EGR31087.1 - 0.00062 19.8 5.3 0.23 11.5 0.2 4.0 4 0 0 4 4 3 1 Protein of unknown function (DUF1192) CEP63 PF17045.5 EGR31087.1 - 0.00066 19.7 30.6 0.06 13.2 11.4 2.7 1 1 1 2 2 2 2 Centrosomal protein of 63 kDa Fez1 PF06818.15 EGR31087.1 - 0.00097 19.6 24.9 0.14 12.6 9.8 2.2 1 1 1 2 2 2 2 Fez1 Death_2 PF14786.6 EGR31087.1 - 0.012 15.5 0.4 0.038 13.9 0.4 1.9 1 1 0 1 1 1 0 Tube Death domain bZIP_1 PF00170.21 EGR31087.1 - 0.027 14.6 0.9 0.027 14.6 0.9 4.9 2 1 3 5 5 5 0 bZIP transcription factor DUF2730 PF10805.8 EGR31087.1 - 0.05 13.7 7.3 0.59 10.3 0.4 3.8 2 2 1 3 3 3 0 Protein of unknown function (DUF2730) DUF3584 PF12128.8 EGR31087.1 - 0.074 10.6 24.3 0.09 10.3 24.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Tup_N PF08581.10 EGR31087.1 - 0.08 13.3 26.2 6.7 7.1 4.5 4.8 1 1 3 4 4 4 0 Tup N-terminal MAD PF05557.13 EGR31087.1 - 0.081 11.3 32.8 0.051 11.9 14.3 2.4 1 1 1 2 2 2 0 Mitotic checkpoint protein FUSC PF04632.12 EGR31087.1 - 0.096 11.2 0.2 0.12 10.9 0.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family CENP-F_leu_zip PF10473.9 EGR31087.1 - 0.15 12.0 23.7 0.48 10.4 18.4 3.2 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 EGR31087.1 - 0.18 12.1 23.0 1.7 8.9 9.9 2.9 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DASH_Dad2 PF08654.10 EGR31087.1 - 0.18 12.3 7.6 0.44 11.0 3.2 3.1 2 1 1 3 3 3 0 DASH complex subunit Dad2 HAUS-augmin3 PF14932.6 EGR31087.1 - 0.19 11.3 21.2 1.5 8.4 7.6 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 TACC_C PF05010.14 EGR31087.1 - 0.3 10.9 27.2 0.24 11.2 18.7 2.8 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF1759 PF03564.15 EGR31087.1 - 0.35 10.8 17.9 4.1 7.3 2.1 3.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1759) Spc7 PF08317.11 EGR31087.1 - 0.41 9.5 27.6 0.35 9.7 11.6 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein TPR_MLP1_2 PF07926.12 EGR31087.1 - 0.59 10.2 27.0 1.7 8.7 7.2 3.8 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Exonuc_VII_L PF02601.15 EGR31087.1 - 0.62 9.6 20.7 0.95 9.0 9.9 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit UPF0242 PF06785.11 EGR31087.1 - 0.93 9.6 32.0 0.35 10.9 13.4 3.1 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 EGR31087.1 - 0.93 9.7 30.6 0.066 13.4 9.2 3.4 1 1 1 3 3 3 0 Fibrinogen alpha/beta chain family FlaC_arch PF05377.11 EGR31087.1 - 1.2 9.6 13.9 14 6.2 0.4 4.9 3 1 2 5 5 5 0 Flagella accessory protein C (FlaC) Uso1_p115_C PF04871.13 EGR31087.1 - 1.6 9.1 20.3 1.3 9.4 4.9 3.2 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Peptidase_C10 PF01640.17 EGR31087.1 - 1.9 8.8 6.0 1 9.6 3.5 1.9 1 1 1 2 2 2 0 Peptidase C10 family DUF3450 PF11932.8 EGR31087.1 - 2.2 7.5 23.9 3.2 7.0 5.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Syntaxin-6_N PF09177.11 EGR31087.1 - 2.7 8.6 16.7 95 3.6 13.5 3.3 1 1 1 2 2 2 0 Syntaxin 6, N-terminal BLOC1_2 PF10046.9 EGR31087.1 - 2.8 8.3 25.9 1 9.7 1.9 4.5 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1664 PF07889.12 EGR31087.1 - 3.8 7.6 14.0 0.77 9.8 3.0 3.4 1 1 4 5 5 5 0 Protein of unknown function (DUF1664) DUF4200 PF13863.6 EGR31087.1 - 3.8 7.9 30.3 29 5.1 7.4 3.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) NYD-SP28_assoc PF14775.6 EGR31088.1 - 3.9e-05 23.7 5.4 3.9e-05 23.7 5.4 4.0 4 0 0 4 4 4 1 Sperm tail C-terminal domain Presenilin PF01080.17 EGR31089.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Presenilin Semialdhyde_dhC PF02774.18 EGR31089.1 - 0.2 11.7 2.1 0.33 11.0 2.1 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain Goodbye PF17109.5 EGR31089.1 - 0.27 11.7 1.4 10 6.6 0.0 3.3 3 1 0 3 3 3 0 fungal STAND N-terminal Goodbye domain Pex14_N PF04695.13 EGR31089.1 - 2.2 8.9 13.3 3.5 8.3 13.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LRR_8 PF13855.6 EGR31090.1 - 0.0039 16.9 2.2 0.0039 16.9 2.2 5.6 5 2 0 5 5 5 1 Leucine rich repeat LRR_4 PF12799.7 EGR31090.1 - 0.012 16.1 0.4 0.012 16.1 0.4 7.0 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) Alpha-amylase PF00128.24 EGR31091.1 - 2.4e-55 188.4 2.0 1e-54 186.4 2.0 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain GHL10 PF02638.15 EGR31091.1 - 0.0087 15.2 0.0 0.02 14.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase-like 10 GHL6 PF14871.6 EGR31091.1 - 0.035 14.2 0.0 3.2 7.9 0.0 2.8 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 Abhydrolase_3 PF07859.13 EGR31093.1 - 3.8e-28 98.8 0.0 4.6e-28 98.5 0.0 1.0 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGR31093.1 - 0.00024 20.1 0.1 0.00034 19.6 0.1 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase DUF3089 PF11288.8 EGR31093.1 - 0.032 13.8 0.0 0.045 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Kelch_5 PF13854.6 EGR31094.1 - 9.4e-30 102.1 2.7 3.3e-05 23.7 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EGR31094.1 - 2.4e-27 94.6 4.4 3.9e-07 30.2 0.1 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.6 EGR31094.1 - 1.8e-22 79.1 6.0 8.8e-07 28.8 0.2 5.7 6 0 0 6 6 6 4 Galactose oxidase, central domain Metallophos PF00149.28 EGR31094.1 - 8.5e-17 62.3 1.8 8.5e-17 62.3 1.8 2.8 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Kelch_2 PF07646.15 EGR31094.1 - 4.4e-11 42.3 4.2 0.005 16.8 0.0 6.0 6 0 0 6 6 6 2 Kelch motif Kelch_1 PF01344.25 EGR31094.1 - 1.2e-10 40.8 1.5 0.075 12.6 0.0 6.1 6 0 0 6 6 6 2 Kelch motif Kelch_6 PF13964.6 EGR31094.1 - 2.5e-10 40.3 6.5 0.52 10.7 0.0 5.6 5 0 0 5 5 5 4 Kelch motif STPPase_N PF16891.5 EGR31094.1 - 0.00078 19.8 0.0 0.0024 18.3 0.0 1.9 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain RAG2 PF03089.14 EGR31094.1 - 0.0038 16.3 8.3 0.14 11.1 0.0 3.9 3 2 2 5 5 5 2 Recombination activating protein 2 DUF647 PF04884.14 EGR31094.1 - 0.081 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Vitamin B6 photo-protection and homoeostasis Ephrin_lbd PF01404.19 EGR31094.1 - 0.53 10.3 7.4 0.1 12.6 3.0 2.0 2 0 0 2 2 2 0 Ephrin receptor ligand binding domain TIM PF00121.18 EGR31095.1 - 1.2e-87 293.4 0.6 1.3e-87 293.2 0.6 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase FAE1_CUT1_RppA PF08392.12 EGR31095.1 - 0.0016 17.8 0.1 0.0031 16.8 0.1 1.4 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Pkinase PF00069.25 EGR31096.1 - 8e-14 51.6 0.0 9.6e-14 51.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31096.1 - 2.8e-06 26.8 0.0 2.9e-06 26.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR31096.1 - 0.00057 18.8 0.0 0.00062 18.7 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase ADH_zinc_N PF00107.26 EGR31097.1 - 4.3e-17 62.3 0.0 7e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGR31097.1 - 2.9e-07 30.3 0.0 3.4e-06 26.9 0.0 2.3 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGR31097.1 - 0.00043 21.3 0.0 0.001 20.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase EIIA-man PF03610.16 EGR31097.1 - 0.0022 18.2 1.2 0.19 12.0 0.4 3.1 1 1 1 2 2 2 1 PTS system fructose IIA component SMC_N PF02463.19 EGR31097.1 - 0.024 14.1 0.5 0.034 13.6 0.5 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain adh_short_C2 PF13561.6 EGR31097.1 - 0.037 13.6 0.0 2.6 7.5 0.0 2.2 1 1 1 2 2 2 0 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.18 EGR31097.1 - 0.089 13.1 0.1 0.18 12.0 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.15 EGR31097.1 - 0.1 12.7 0.4 0.23 11.6 0.4 1.7 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF1479 PF07350.12 EGR31097.1 - 0.15 10.8 0.5 0.95 8.2 0.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1479) Ribosomal_S2 PF00318.20 EGR31098.1 - 4.2e-30 104.6 9.8 2e-15 56.6 0.1 2.6 2 1 1 3 3 3 2 Ribosomal protein S2 Pkinase PF00069.25 EGR31100.1 - 4.1e-62 209.9 1.9 4.9e-62 209.7 1.9 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31100.1 - 2.2e-30 105.8 0.2 2.8e-30 105.5 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR31100.1 - 4.4e-05 23.5 0.0 0.4 10.6 0.0 2.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 EGR31100.1 - 0.033 13.6 0.3 0.1 12.0 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF3536 PF12055.8 EGR31100.1 - 0.094 12.0 0.2 0.15 11.4 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3536) HP0268 PF18618.1 EGR31100.1 - 0.28 11.6 4.5 0.31 11.5 0.1 2.9 2 2 1 3 3 3 0 HP0268 Bax1-I PF01027.20 EGR31101.1 - 3.6e-14 53.1 29.6 4.7e-14 52.7 29.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 GCS PF03074.16 EGR31102.1 - 2.7e-137 458.0 4.5 2.7e-137 458.0 4.5 1.7 2 0 0 2 2 2 1 Glutamate-cysteine ligase EssA PF10661.9 EGR31102.1 - 0.35 10.7 4.3 2 8.3 0.1 2.7 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA MORN PF02493.20 EGR31103.1 - 1.7e-46 153.4 82.5 6.6e-08 32.0 4.4 9.8 10 0 0 10 10 10 9 MORN repeat IQ PF00612.27 EGR31103.1 - 0.013 15.2 0.2 0.026 14.3 0.2 1.5 1 0 0 1 1 1 0 IQ calmodulin-binding motif Tudor_2 PF18104.1 EGR31103.1 - 5.7 6.7 17.3 1.1 9.0 0.5 4.8 4 1 1 5 5 5 0 Jumonji domain-containing protein 2A Tudor domain Kinesin PF00225.23 EGR31104.1 - 5e-92 308.4 9.5 7.5e-92 307.8 9.5 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR31104.1 - 7.7e-22 77.8 2.1 7.7e-22 77.8 2.1 2.2 2 0 0 2 2 2 1 Microtubule binding ResIII PF04851.15 EGR31104.1 - 0.59 10.1 5.2 0.22 11.5 1.1 2.2 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Phage_Mu_Gam PF07352.12 EGR31104.1 - 1.3 9.0 7.0 9.8 6.1 3.2 2.3 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein Orn_Arg_deC_N PF02784.16 EGR31105.1 - 1.3e-24 86.9 0.0 2.3e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain DUF1804 PF08822.11 EGR31105.1 - 0.00041 20.4 0.4 0.15 12.0 0.2 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1804) adh_short_C2 PF13561.6 EGR31106.1 - 5.1e-57 193.1 0.2 6.2e-57 192.9 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGR31106.1 - 1e-44 152.3 0.5 1.3e-44 152.0 0.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGR31106.1 - 2.3e-10 40.7 0.1 3e-10 40.3 0.1 1.1 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EGR31106.1 - 0.018 14.4 0.0 0.026 13.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGR31106.1 - 0.035 13.3 0.1 0.047 12.8 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 EGR31106.1 - 0.1 12.1 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family CdAMP_rec PF06153.11 EGR31106.1 - 0.1 12.8 0.2 0.42 10.8 0.1 2.0 2 0 0 2 2 2 0 Cyclic-di-AMP receptor DUF1598 PF07643.11 EGR31106.1 - 0.14 12.4 0.0 0.44 10.8 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1598) DNA_processg_A PF02481.15 EGR31106.1 - 0.16 11.2 0.7 0.34 10.1 0.0 1.8 2 0 0 2 2 2 0 DNA recombination-mediator protein A Metallophos PF00149.28 EGR31107.1 - 1.1e-29 104.4 1.2 2e-29 103.6 1.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 EGR31107.1 - 1.7e-21 76.3 2.1 4.2e-21 75.0 0.5 2.3 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 EGR31107.1 - 1.1e-19 69.4 2.9 1.7e-06 27.6 0.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGR31107.1 - 4.5e-14 51.3 2.1 4.6e-06 26.3 0.4 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGR31107.1 - 5.4e-10 38.8 1.2 0.0015 18.1 0.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 EGR31107.1 - 9.2e-10 38.0 1.6 5.1e-05 23.2 0.5 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGR31107.1 - 3.2e-07 30.9 0.0 0.051 14.2 0.1 2.3 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGR31107.1 - 9e-06 25.9 0.1 0.013 15.8 0.4 3.0 1 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGR31107.1 - 3.8e-05 23.8 0.0 0.016 15.5 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_21 PF09976.9 EGR31107.1 - 0.00029 20.6 1.0 0.53 10.0 0.2 2.2 2 0 0 2 2 2 2 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 EGR31107.1 - 0.0035 17.9 3.0 0.021 15.4 0.6 3.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGR31107.1 - 0.0035 18.0 0.0 0.031 15.1 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR31107.1 - 0.0039 17.4 0.2 0.012 15.8 0.2 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EGR31107.1 - 0.036 14.1 0.0 3.6 7.8 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_34 PF11312.8 EGR31107.1 - 0.039 13.2 0.6 0.062 12.5 0.6 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase SHNi-TPR PF10516.9 EGR31107.1 - 0.067 12.7 0.4 5.8 6.5 0.0 3.0 3 0 0 3 3 3 0 SHNi-TPR TPR_19 PF14559.6 EGR31107.1 - 0.075 13.6 0.4 1.5 9.4 0.2 2.4 1 1 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EGR31107.1 - 0.13 12.3 1.0 18 5.5 0.1 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain ATP12 PF07542.11 EGR31108.1 - 2.7e-15 56.6 0.1 5.4e-15 55.6 0.0 1.5 2 0 0 2 2 2 1 ATP12 chaperone protein WD40 PF00400.32 EGR31109.1 - 4.6e-07 30.4 0.4 0.0018 19.1 0.0 4.4 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR31109.1 - 0.00023 21.4 0.2 0.56 10.5 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGR31110.1 - 6.8e-12 45.7 0.1 0.00068 20.4 0.0 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR31110.1 - 1.4e-07 31.7 0.3 0.0014 18.9 0.0 3.4 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGR31110.1 - 0.047 13.7 0.7 3.4 7.7 0.0 3.3 2 2 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Collagen_bind_2 PF12904.7 EGR31110.1 - 0.055 13.5 0.5 0.23 11.4 0.0 2.3 2 0 0 2 2 2 0 Putative collagen-binding domain of a collagenase Astro_capsid_p PF12226.8 EGR31110.1 - 0.15 11.2 21.3 0.27 10.3 21.3 1.5 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CNDH2_C PF16858.5 EGR31110.1 - 0.47 10.3 20.2 0.8 9.5 20.2 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CDC45 PF02724.14 EGR31110.1 - 0.74 8.0 22.8 1 7.6 22.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4820 PF16091.5 EGR31110.1 - 3.8 6.8 12.7 6.5 6.1 12.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) IQ PF00612.27 EGR31111.1 - 4.2e-05 23.0 4.3 6.1e-05 22.5 0.3 2.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif GPAT_N PF14829.6 EGR31111.1 - 0.0037 17.2 0.1 0.074 13.1 0.0 2.7 2 0 0 2 2 2 1 Glycerol-3-phosphate acyltransferase N-terminal TIP41 PF04176.13 EGR31112.1 - 2.8e-10 40.0 1.1 8.1e-10 38.5 1.1 1.7 1 1 0 1 1 1 1 TIP41-like family HSP70 PF00012.20 EGR31113.1 - 1.8e-10 39.7 0.0 3.3e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGR31113.1 - 0.12 11.2 0.0 5.1 5.8 0.0 2.2 2 0 0 2 2 2 0 MreB/Mbl protein Peptidase_M41 PF01434.18 EGR31114.1 - 1.2e-53 181.8 0.0 2.1e-53 181.0 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EGR31114.1 - 6.2e-45 152.9 0.0 1.6e-44 151.5 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) UQ_con PF00179.26 EGR31114.1 - 1.3e-32 112.4 0.1 2.5e-32 111.4 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme AAA_lid_3 PF17862.1 EGR31114.1 - 6e-12 45.2 0.1 1.8e-11 43.7 0.0 1.8 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 EGR31114.1 - 0.00013 22.0 0.0 0.00057 19.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGR31114.1 - 0.00053 20.3 1.5 0.33 11.2 0.1 3.5 3 1 1 4 4 4 1 AAA domain AAA_2 PF07724.14 EGR31114.1 - 0.00098 19.3 0.5 0.0049 17.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EGR31114.1 - 0.0031 16.8 0.1 0.007 15.6 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_14 PF13173.6 EGR31114.1 - 0.0044 17.1 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGR31114.1 - 0.0075 16.0 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGR31114.1 - 0.011 16.1 3.1 0.075 13.4 0.1 2.7 2 1 0 3 3 3 0 AAA ATPase domain IstB_IS21 PF01695.17 EGR31114.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 EGR31114.1 - 0.068 13.3 0.0 0.17 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2309 PF10070.9 EGR31114.1 - 0.074 11.4 0.1 2.6 6.3 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2309) AAA_18 PF13238.6 EGR31114.1 - 0.1 13.1 0.0 0.62 10.6 0.0 2.4 2 0 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 EGR31114.1 - 0.14 11.5 1.6 0.55 9.6 0.2 2.4 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_25 PF13481.6 EGR31114.1 - 0.53 9.8 1.5 7.8 6.0 0.3 2.4 1 1 1 2 2 2 0 AAA domain LMBR1 PF04791.16 EGR31114.1 - 0.57 9.0 1.8 0.92 8.3 1.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein AAA_11 PF13086.6 EGR31114.1 - 0.95 9.2 6.9 0.98 9.1 0.1 2.4 2 0 0 2 2 2 0 AAA domain Peptidase_Prp PF04327.12 EGR31114.1 - 5.3 7.4 5.2 1.9 8.8 0.2 2.6 3 0 0 3 3 2 0 Cysteine protease Prp Med26 PF08711.11 EGR31115.1 - 3e-05 23.9 1.5 4.3e-05 23.5 0.5 1.8 2 0 0 2 2 2 1 TFIIS helical bundle-like domain PFU PF09070.11 EGR31115.1 - 0.016 15.5 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) DUF1704 PF08014.11 EGR31116.1 - 2.5e-12 46.5 2.7 9e-12 44.7 0.0 2.4 3 0 0 3 3 3 2 Domain of unknown function (DUF1704) PhoLip_ATPase_C PF16212.5 EGR31117.1 - 8e-51 173.2 29.0 8e-51 173.2 29.0 2.9 3 1 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGR31117.1 - 4.1e-21 74.4 0.9 4.1e-21 74.4 0.9 2.5 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGR31117.1 - 7.5e-11 42.0 3.7 5e-10 39.3 0.1 3.5 3 1 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGR31117.1 - 2.3e-09 37.9 0.0 1.4e-07 32.1 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase EF-hand_7 PF13499.6 EGR31118.1 - 3.3e-24 85.1 16.2 5.2e-09 36.4 1.6 4.8 4 0 0 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EGR31118.1 - 5.2e-20 69.6 15.5 0.001 18.9 0.1 7.5 6 1 0 6 6 6 5 EF-hand domain EF-hand_1 PF00036.32 EGR31118.1 - 4e-15 54.1 18.8 0.00067 19.0 0.2 7.2 7 0 0 7 7 7 5 EF hand EF-hand_5 PF13202.6 EGR31118.1 - 2.9e-08 32.8 9.6 0.01 15.3 0.1 5.7 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 EGR31118.1 - 2.7e-06 27.1 11.7 0.093 12.6 0.1 5.2 3 2 2 5 5 5 3 EF-hand domain pair DUF3731 PF12531.8 EGR31118.1 - 0.022 14.6 0.6 0.058 13.2 0.3 1.9 1 1 0 1 1 1 0 DNA-K related protein DIX PF00778.17 EGR31118.1 - 0.035 14.0 4.2 2.6 8.0 0.0 4.9 4 2 2 6 6 6 0 DIX domain HU-CCDC81_bac_2 PF18175.1 EGR31118.1 - 0.063 13.1 0.9 1.4 8.8 0.3 3.6 2 1 1 3 3 3 0 CCDC81-like prokaryotic HU domain 2 Peptidase_C2 PF00648.21 EGR31119.1 - 3.8e-10 39.3 3.0 5.1e-10 38.9 0.1 2.7 3 1 0 3 3 3 1 Calpain family cysteine protease Pkinase PF00069.25 EGR31122.1 - 8.4e-71 238.4 0.3 8.4e-71 238.4 0.3 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31122.1 - 1.9e-38 132.3 0.0 3.5e-38 131.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR31122.1 - 0.0025 16.7 1.9 0.0029 16.5 0.0 1.9 2 1 1 3 3 3 1 Fungal protein kinase FTA2 PF13095.6 EGR31122.1 - 0.062 12.9 0.1 0.062 12.9 0.1 3.4 3 2 1 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 WD40 PF00400.32 EGR31123.1 - 4.7e-60 198.1 29.0 4.1e-09 36.9 0.1 9.0 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR31123.1 - 8.3e-20 70.9 3.2 0.00028 21.1 0.3 6.0 2 2 5 7 7 7 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 EGR31123.1 - 7.5e-10 39.2 1.0 1.4e-09 38.3 1.0 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.11 EGR31123.1 - 3.8e-09 36.7 0.2 0.0046 16.8 0.0 3.6 3 1 1 4 4 4 2 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGR31123.1 - 7.3e-07 28.5 0.1 0.007 15.4 0.0 3.9 3 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGR31123.1 - 0.00016 21.5 0.1 20 5.2 0.0 5.1 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Nbas_N PF15492.6 EGR31123.1 - 0.00061 19.2 0.6 3.3 7.0 0.0 3.9 2 2 1 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.9 EGR31123.1 - 0.0011 18.6 0.5 12 5.7 0.1 4.4 4 0 0 4 4 4 1 Proteasome subunit A N-terminal signature WD40_like PF17005.5 EGR31123.1 - 0.0016 17.8 0.0 1.9 7.7 0.0 3.5 4 0 0 4 4 4 1 WD40-like domain Nucleoporin_N PF08801.11 EGR31123.1 - 0.003 16.4 1.7 0.45 9.2 0.0 3.0 3 1 0 3 3 3 2 Nup133 N terminal like Mito_carr PF00153.27 EGR31124.1 - 3.8e-36 122.9 0.5 3.2e-13 49.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Colicin-DNase PF12639.7 EGR31124.1 - 0.003 18.3 0.0 0.012 16.4 0.1 2.0 2 0 0 2 2 2 1 DNase/tRNase domain of colicin-like bacteriocin Peptidase_M48_N PF16491.5 EGR31124.1 - 0.0066 16.4 0.1 0.015 15.2 0.0 1.4 1 1 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices DUF2536 PF10750.9 EGR31124.1 - 0.18 11.7 5.0 0.084 12.8 1.7 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2536) Pkinase PF00069.25 EGR31125.1 - 1.2e-27 96.9 0.0 1.5e-27 96.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31125.1 - 1.9e-16 60.1 0.0 2.2e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR31125.1 - 8.9e-09 34.6 0.0 1.2e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR31125.1 - 0.0099 15.8 0.0 0.036 14.0 0.0 1.9 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR31125.1 - 0.047 13.0 0.0 0.074 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C3HC4_2 PF13923.6 EGR31126.1 - 9.1e-11 41.4 11.5 1.9e-10 40.4 11.5 1.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGR31126.1 - 2.4e-10 40.1 7.7 3.6e-10 39.5 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGR31126.1 - 2.3e-08 33.9 6.3 2.3e-08 33.9 6.3 1.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGR31126.1 - 5.1e-08 33.1 10.3 7.8e-08 32.5 10.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGR31126.1 - 3.5e-07 30.0 12.0 5.6e-07 29.3 12.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGR31126.1 - 3e-06 27.3 9.6 9e-06 25.8 9.8 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGR31126.1 - 3.9e-05 23.5 10.2 8.1e-05 22.5 10.2 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_10 PF16685.5 EGR31126.1 - 6.7e-05 23.0 6.2 0.00013 22.0 6.2 1.6 1 1 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_6 PF14835.6 EGR31126.1 - 0.00019 21.2 3.0 0.00019 21.2 3.0 1.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 EGR31126.1 - 0.00059 19.6 8.3 0.0012 18.7 8.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGR31126.1 - 0.016 15.4 9.1 0.034 14.4 9.1 1.6 1 1 0 1 1 1 0 RING-H2 zinc finger domain FYVE PF01363.21 EGR31126.1 - 0.64 10.2 5.4 1.5 9.1 5.4 1.9 1 1 0 1 1 1 0 FYVE zinc finger zf-RING_4 PF14570.6 EGR31126.1 - 2.3 8.1 10.2 1.5 8.7 7.8 2.0 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.11 EGR31126.1 - 8.9 6.5 10.2 4.5 7.4 7.5 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1272) UQ_con PF00179.26 EGR31127.1 - 4.3e-37 126.9 0.9 5.9e-37 126.4 0.9 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGR31127.1 - 0.09 13.1 1.1 0.19 12.0 0.4 2.1 1 1 0 1 1 1 0 RWD domain Aldo_ket_red PF00248.21 EGR31128.1 - 2.3e-70 237.1 0.0 2.6e-70 237.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 EGR31129.1 - 4.1e-73 246.1 0.0 4.7e-73 245.9 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family LRR_6 PF13516.6 EGR31130.1 - 0.034 14.2 0.1 0.077 13.1 0.1 1.7 1 0 0 1 1 1 0 Leucine Rich repeat RINGv PF12906.7 EGR31131.1 - 3.4e-13 49.5 3.9 7e-13 48.5 3.9 1.6 1 0 0 1 1 1 1 RING-variant domain FHA PF00498.26 EGR31131.1 - 6.4e-13 48.8 3.6 2.3e-12 47.1 0.3 2.8 2 1 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EGR31131.1 - 8.9e-08 32.4 0.1 1.1e-06 28.8 0.1 2.2 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_2 PF13639.6 EGR31131.1 - 0.011 16.1 6.6 0.016 15.5 4.8 2.3 2 1 1 3 3 3 0 Ring finger domain FANCL_C PF11793.8 EGR31131.1 - 0.03 14.5 2.6 0.061 13.5 2.6 1.5 1 0 0 1 1 1 0 FANCL C-terminal domain Fe-S_biosyn PF01521.20 EGR31132.1 - 7e-19 68.1 0.2 9.3e-19 67.7 0.2 1.2 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis PP2C PF00481.21 EGR31134.1 - 3.8e-45 154.5 0.0 5e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGR31134.1 - 0.00056 19.6 0.0 0.0016 18.1 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SNAD3 PF18749.1 EGR31134.1 - 0.0089 15.2 0.1 0.018 14.3 0.1 1.4 1 0 0 1 1 1 1 Secreted Novel AID/APOBEC-like Deaminase 3 WD40 PF00400.32 EGR31135.1 - 8e-69 225.9 8.5 5.9e-08 33.2 0.0 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR31135.1 - 1.4e-21 76.5 0.3 0.0025 18.1 0.0 7.0 1 1 7 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGR31135.1 - 1.2e-12 47.7 1.8 0.0047 16.3 0.1 4.5 2 1 2 4 4 4 4 WD40-like domain eIF2A PF08662.11 EGR31135.1 - 2.6e-09 37.2 3.2 0.0029 17.5 0.1 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGR31135.1 - 1.2e-05 24.5 4.0 0.52 9.2 0.0 5.2 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGR31135.1 - 1.8e-05 23.6 2.4 1.2 7.7 0.0 5.4 3 2 4 7 7 7 2 Nucleoporin Nup120/160 CEP19 PF14933.6 EGR31135.1 - 0.00021 21.7 0.0 0.0003 21.1 0.0 1.2 1 0 0 1 1 1 1 CEP19-like protein Frtz PF11768.8 EGR31135.1 - 0.0042 15.5 0.1 3.2 5.9 0.0 3.6 4 1 1 5 5 5 1 WD repeat-containing and planar cell polarity effector protein Fritz WD40_3 PF15911.5 EGR31135.1 - 0.0044 17.0 0.1 0.47 10.5 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat Nucleoporin_N PF08801.11 EGR31135.1 - 0.12 11.1 0.1 13 4.4 0.0 2.9 2 1 1 3 3 3 0 Nup133 N terminal like YjeJ PF15922.5 EGR31137.1 - 0.044 13.0 0.7 0.046 12.9 0.7 1.0 1 0 0 1 1 1 0 YjeJ-like Pkinase PF00069.25 EGR31138.1 - 1.3e-53 182.1 4.3 9.2e-53 179.3 4.3 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31138.1 - 1.2e-21 77.2 0.2 1.8e-21 76.6 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Phage_gp53 PF11246.8 EGR31138.1 - 0.0015 18.2 1.8 0.003 17.3 1.8 1.5 1 0 0 1 1 1 1 Base plate wedge protein 53 Choline_kinase PF01633.20 EGR31138.1 - 0.0093 15.6 1.3 0.024 14.2 1.3 1.7 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EGR31138.1 - 0.018 15.0 0.0 0.044 13.7 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family EMP24_GP25L PF01105.24 EGR31139.1 - 1.8e-21 76.9 0.3 1.9e-21 76.8 0.3 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD LRR_4 PF12799.7 EGR31140.1 - 0.00072 19.9 4.2 0.00072 19.9 4.2 5.0 3 2 1 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGR31140.1 - 0.002 18.4 15.9 3 8.7 0.1 6.9 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_6 PF13516.6 EGR31140.1 - 0.013 15.5 26.0 1.2 9.4 1.5 6.5 6 0 0 6 6 6 0 Leucine Rich repeat LRR_8 PF13855.6 EGR31140.1 - 0.047 13.5 21.9 0.13 12.1 0.2 5.4 3 1 1 4 4 4 0 Leucine rich repeat PRP1_N PF06424.12 EGR31141.1 - 3.1e-35 121.8 20.6 9.5e-27 94.2 8.6 3.1 2 1 1 3 3 3 2 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EGR31141.1 - 1.6e-18 65.8 11.7 0.38 11.7 0.1 11.5 5 3 7 12 12 12 6 Tetratricopeptide repeat TPR_19 PF14559.6 EGR31141.1 - 1.9e-14 53.9 12.6 0.0017 18.8 0.0 8.9 8 1 1 9 9 9 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGR31141.1 - 0.00037 21.1 0.0 7.2 7.4 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGR31141.1 - 0.0084 16.3 18.8 4.4 7.8 0.1 8.7 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGR31141.1 - 0.029 14.7 7.0 16 6.2 0.0 7.1 9 0 0 9 9 9 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGR31141.1 - 0.25 11.5 1.9 12 6.1 0.0 4.3 5 1 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR31141.1 - 4.5 7.6 8.7 36 4.7 1.1 5.3 6 1 1 7 7 7 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EGR31141.1 - 7.6 6.9 23.0 39 4.7 0.0 8.7 11 0 0 11 11 11 0 Tetratricopeptide repeat Cyclin_N PF00134.23 EGR31142.1 - 1.2e-26 92.9 2.6 1.2e-26 92.9 2.6 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGR31142.1 - 3.7e-05 23.8 0.7 3.7e-05 23.8 0.7 2.3 2 0 0 2 2 2 1 Cyclin, C-terminal domain PhoLip_ATPase_C PF16212.5 EGR31144.1 - 7.3e-48 163.5 32.0 7.3e-48 163.5 32.0 3.3 2 1 1 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGR31144.1 - 2.4e-17 62.4 0.4 2.4e-17 62.4 0.4 3.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGR31144.1 - 6.8e-11 42.9 1.3 0.00035 20.9 0.0 3.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGR31144.1 - 9.2e-09 35.3 0.4 3.4e-07 30.3 0.1 2.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGR31144.1 - 0.00041 19.9 0.0 0.00041 19.9 0.0 2.5 2 0 0 2 2 2 1 E1-E2 ATPase Pkinase PF00069.25 EGR31146.1 - 1.4e-28 100.0 2.4 6.8e-28 97.8 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31146.1 - 4.7e-15 55.6 0.1 5.9e-15 55.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L20 PF00453.18 EGR31146.1 - 0.034 14.2 0.1 0.048 13.7 0.1 1.2 1 0 0 1 1 1 0 Ribosomal protein L20 Glyco_transf_4 PF13439.6 EGR31148.1 - 7.8e-08 32.5 0.0 1.3e-07 31.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EGR31148.1 - 1.7e-07 31.0 0.0 8.1e-05 22.2 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGR31148.1 - 0.11 13.0 0.0 0.15 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Pkinase PF00069.25 EGR31149.1 - 1.5e-73 247.5 0.1 1.7e-73 247.2 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31149.1 - 3e-41 141.4 0.0 3.4e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31149.1 - 0.00016 21.1 0.1 0.00038 19.9 0.1 1.8 1 1 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 EGR31149.1 - 0.0011 18.0 3.0 0.0023 17.0 2.9 1.6 1 1 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.23 EGR31149.1 - 0.01 15.8 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGR31149.1 - 0.03 13.1 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EGR31149.1 - 0.05 12.5 0.8 0.1 11.5 0.8 1.6 1 1 0 1 1 1 0 Haspin like kinase domain Senescence PF06911.12 EGR31150.1 - 3.5e-29 102.4 7.7 4.7e-29 102.0 7.7 1.2 1 0 0 1 1 1 1 Senescence-associated protein TFIIS_C PF01096.18 EGR31151.1 - 4e-14 52.2 3.6 4e-14 52.2 3.6 1.7 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) FHIPEP PF00771.20 EGR31151.1 - 0.00089 17.9 1.5 0.0013 17.3 1.4 1.3 1 1 0 1 1 1 1 FHIPEP family TMF_DNA_bd PF12329.8 EGR31151.1 - 0.043 13.8 3.0 0.74 9.9 0.3 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding SpoIISA_toxin PF14171.6 EGR31151.1 - 0.19 11.4 3.5 0.26 11.0 3.5 1.1 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system WD40 PF00400.32 EGR31152.1 - 2.2e-11 44.1 0.8 0.00087 20.1 0.0 4.0 4 0 0 4 4 4 2 WD domain, G-beta repeat MqsR_toxin PF15723.5 EGR31152.1 - 0.047 14.1 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 Motility quorum-sensing regulator, toxin of MqsA Hira PF07569.11 EGR31152.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 TUP1-like enhancer of split WD40 PF00400.32 EGR31153.1 - 3.6e-15 56.1 10.2 0.27 12.2 0.0 12.2 12 0 0 12 12 12 3 WD domain, G-beta repeat HELP PF03451.14 EGR31153.1 - 1.1e-10 41.3 0.3 0.00064 19.5 0.1 3.6 3 0 0 3 3 3 2 HELP motif ANAPC4_WD40 PF12894.7 EGR31153.1 - 8e-09 35.7 3.6 0.0018 18.5 0.0 7.2 6 2 2 8 8 8 1 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_6 PF13405.6 EGR31153.1 - 0.0081 16.0 3.7 0.096 12.7 0.1 3.2 2 0 0 2 2 2 1 EF-hand domain BMP2K_C PF15282.6 EGR31153.1 - 0.28 11.0 6.6 0.68 9.8 4.3 2.5 2 0 0 2 2 2 0 BMP-2-inducible protein kinase C-terminus EF-hand_1 PF00036.32 EGR31153.1 - 1.6 8.4 4.1 0.54 9.9 0.1 2.5 2 0 0 2 2 2 0 EF hand Peptidase_M1 PF01433.20 EGR31154.1 - 1.5e-45 155.5 2.0 2.8e-45 154.6 2.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EGR31154.1 - 1.8e-26 93.5 3.7 3.2e-26 92.6 3.7 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Leuk-A4-hydro_C PF09127.11 EGR31154.1 - 1.9e-14 53.7 0.6 1.1e-13 51.3 0.1 2.5 2 0 0 2 2 2 1 Leukotriene A4 hydrolase, C-terminal DUF4806 PF16064.5 EGR31154.1 - 0.12 12.7 2.2 0.34 11.3 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4806) SlyX PF04102.12 EGR31155.1 - 0.0053 17.3 3.0 0.0053 17.3 3.0 5.6 5 1 1 6 6 6 1 SlyX YabA PF06156.13 EGR31155.1 - 0.025 15.2 6.3 0.025 15.2 6.3 6.2 4 1 2 6 6 6 0 Initiation control protein YabA Cytochrome_P460 PF16694.5 EGR31155.1 - 0.12 12.8 0.3 0.12 12.8 0.3 2.4 2 0 0 2 2 2 0 Cytochrome P460 ApoO PF09769.9 EGR31155.1 - 0.36 10.8 3.2 5.5 7.0 0.4 3.0 2 0 0 2 2 2 0 Apolipoprotein O DPM3 PF08285.11 EGR31155.1 - 1.5 9.0 8.3 7.9 6.7 0.3 3.6 2 1 1 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) HrpB7 PF09486.10 EGR31155.1 - 4.3 7.7 8.2 4.7 7.6 0.1 2.9 3 0 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) vATP-synt_AC39 PF01992.16 EGR31156.1 - 1.1e-74 251.9 9.3 1.6e-74 251.5 9.3 1.1 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Abhydrolase_2 PF02230.16 EGR31157.1 - 1.4e-21 77.3 0.0 1.7e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 EGR31157.1 - 0.0013 18.4 0.0 0.0031 17.2 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.7 EGR31157.1 - 0.008 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGR31157.1 - 0.018 14.7 0.2 4.8 6.8 0.0 2.1 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.8 EGR31157.1 - 0.046 13.3 0.0 1.1 8.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) Hydrolase_4 PF12146.8 EGR31157.1 - 0.059 12.6 0.0 1.5 8.1 0.0 2.0 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Glug PF07581.12 EGR31157.1 - 0.14 12.6 0.2 0.33 11.4 0.2 1.6 1 0 0 1 1 1 0 The GLUG motif Abhydrolase_3 PF07859.13 EGR31157.1 - 0.21 11.4 0.0 0.34 10.7 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Amidinotransf PF02274.17 EGR31158.1 - 4.5e-40 137.8 9.0 1.2e-32 113.3 0.3 3.0 1 1 1 2 2 2 2 Amidinotransferase Hom_end_hint PF05203.16 EGR31158.1 - 0.0094 15.9 0.4 0.0099 15.8 0.4 1.3 1 1 0 1 1 1 1 Hom_end-associated Hint DUF3418 PF11898.8 EGR31158.1 - 0.03 13.0 0.1 0.04 12.6 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3418) Imm70 PF15601.6 EGR31158.1 - 0.041 13.4 0.1 0.14 11.7 0.2 1.8 2 0 0 2 2 2 0 Immunity protein 70 Sod_Fe_C PF02777.18 EGR31158.1 - 0.089 13.0 0.1 0.3 11.3 0.1 1.9 1 0 0 1 1 1 0 Iron/manganese superoxide dismutases, C-terminal domain Nucleoside_tran PF01733.18 EGR31160.1 - 9.7e-22 77.7 18.2 1.6e-21 77.0 18.2 1.2 1 0 0 1 1 1 1 Nucleoside transporter MFS_1 PF07690.16 EGR31160.1 - 2.7e-07 29.8 34.1 6e-06 25.4 14.9 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily MtrC PF04211.13 EGR31160.1 - 0.36 9.9 8.5 0.039 13.0 1.2 2.3 1 1 1 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit C Spc7 PF08317.11 EGR31161.1 - 0.00016 20.6 23.6 0.00016 20.6 23.6 2.0 1 1 1 2 2 2 1 Spc7 kinetochore protein Lge1 PF11488.8 EGR31161.1 - 0.014 15.6 6.4 0.014 15.6 6.4 3.4 1 1 2 3 3 3 0 Transcriptional regulatory protein LGE1 CEP63 PF17045.5 EGR31161.1 - 0.018 15.0 33.7 0.02 14.8 33.7 1.0 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa SpecificRecomb PF10136.9 EGR31161.1 - 0.5 8.6 6.7 0.58 8.4 6.7 1.1 1 0 0 1 1 1 0 Site-specific recombinase Noelin-1 PF12308.8 EGR31161.1 - 1.2 9.1 20.1 0.74 9.8 2.6 2.7 1 1 1 2 2 2 0 Neurogenesis glycoprotein DUF2937 PF11157.8 EGR31161.1 - 2.4 7.8 7.6 1.6 8.4 5.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) APG6_N PF17675.1 EGR31161.1 - 4.4 7.8 37.5 1.7 9.2 25.0 2.7 1 1 1 2 2 2 0 Apg6 coiled-coil region MCPsignal PF00015.21 EGR31161.1 - 7.7 6.3 12.6 8 6.2 2.0 2.1 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain V_ATPase_I PF01496.19 EGR31162.1 - 2e-244 813.3 12.8 2.5e-244 813.0 12.8 1.1 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Guanylate_cyc_2 PF09778.9 EGR31162.1 - 0.14 11.5 1.4 1.6 8.1 0.5 2.2 2 0 0 2 2 2 0 Guanylylate cyclase YceD PF02620.17 EGR31162.1 - 0.21 11.7 0.4 0.41 10.8 0.4 1.4 1 0 0 1 1 1 0 Large ribosomal RNA subunit accumulation protein YceD FAD_binding_1 PF00667.20 EGR31163.1 - 2.7e-38 131.8 0.9 5.7e-38 130.7 0.9 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EGR31163.1 - 7.7e-30 104.0 0.0 1.3e-29 103.2 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin Flavodoxin_3 PF12641.7 EGR31163.1 - 0.019 14.6 0.0 0.047 13.4 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain Flavodoxin_5 PF12724.7 EGR31163.1 - 0.032 14.5 0.0 1.6 9.0 0.0 2.5 1 1 1 2 2 2 0 Flavodoxin domain Complex1_LYR_2 PF13233.6 EGR31163.1 - 0.61 10.9 3.2 6.6 7.6 0.1 3.1 3 1 0 3 3 3 0 Complex1_LYR-like Histone PF00125.24 EGR31164.1 - 2.2e-14 53.9 0.0 4.1e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EGR31164.1 - 1e-11 44.3 0.4 1e-11 44.3 0.4 2.2 2 0 0 2 2 2 1 C-terminus of histone H2A EF-hand_6 PF13405.6 EGR31165.1 - 4.7e-19 66.6 5.5 2.4e-08 33.2 0.2 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 EGR31165.1 - 4.4e-18 63.4 6.5 1e-07 31.0 0.2 4.8 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EGR31165.1 - 2.4e-17 63.1 7.2 3.5e-11 43.4 0.4 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGR31165.1 - 1.3e-08 33.9 3.3 3.5e-05 23.1 0.3 3.7 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 EGR31165.1 - 3e-07 30.7 0.0 0.0015 18.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_14 PF17959.1 EGR31165.1 - 2.7e-06 27.6 6.3 0.00086 19.6 0.3 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGR31165.1 - 4.3e-06 26.5 12.1 0.0043 16.9 1.0 4.7 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 EGR31165.1 - 0.00073 19.4 5.9 0.16 11.9 0.1 3.3 2 1 2 4 4 4 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.10 EGR31165.1 - 0.026 14.6 2.0 1.6 8.9 0.0 3.3 4 0 0 4 4 4 0 Ca2+ insensitive EF hand DUF2767 PF10965.8 EGR31165.1 - 0.034 14.1 0.1 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2767) MutS_II PF05188.17 EGR31165.1 - 0.066 13.5 1.6 2 8.7 0.1 2.4 2 1 0 2 2 2 0 MutS domain II Glycos_trans_3N PF02885.17 EGR31165.1 - 0.67 9.8 4.9 1.5 8.7 0.1 3.2 5 0 0 5 5 5 0 Glycosyl transferase family, helical bundle domain SUB1_ProdP9 PF18213.1 EGR31165.1 - 1.6 8.6 7.1 0.22 11.4 0.5 2.7 2 1 0 3 3 3 0 SUB1 protease Prodomain ProdP9 HTH_40 PF14493.6 EGR31165.1 - 2.2 8.8 8.4 1.4 9.4 0.5 3.2 2 1 1 3 3 3 0 Helix-turn-helix domain VIT1 PF01988.19 EGR31166.1 - 9.5e-59 198.9 0.1 1.2e-58 198.6 0.1 1.1 1 0 0 1 1 1 1 VIT family EcoEI_R_C PF08463.10 EGR31166.1 - 0.0051 17.0 0.0 0.0085 16.2 0.0 1.3 1 0 0 1 1 1 1 EcoEI R protein C-terminal Integrin_b_cyt PF08725.11 EGR31166.1 - 0.097 12.4 2.1 1.6 8.4 0.4 2.3 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain SAVED PF18145.1 EGR31166.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 SMODS-associated and fused to various effectors sensor domain Endonuc-dimeris PF09124.10 EGR31166.1 - 0.13 12.4 0.1 0.29 11.3 0.1 1.5 1 0 0 1 1 1 0 T4 recombination endonuclease VII, dimerisation DUF1700 PF08006.11 EGR31166.1 - 9.5 5.7 8.6 22 4.5 8.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1700) SOR PF07682.11 EGR31168.1 - 0.023 13.6 0.0 0.027 13.4 0.0 1.2 1 0 0 1 1 1 0 Sulphur oxygenase reductase CH_2 PF06294.11 EGR31169.1 - 1.6e-21 76.2 0.8 1.6e-21 76.2 0.8 3.5 3 0 0 3 3 3 1 CH-like domain in sperm protein EF-hand_9 PF14658.6 EGR31169.1 - 0.045 14.1 0.0 0.19 12.1 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain Hydin_ADK PF17213.3 EGR31169.1 - 5.2 7.3 0.0 5.2 7.3 0.0 5.4 4 1 0 4 4 4 0 Hydin Adenylate kinase-like domain VPS13_C PF16909.5 EGR31170.1 - 1.8e-06 27.8 0.3 1.8e-06 27.8 0.3 2.1 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal CutC PF03932.14 EGR31171.1 - 1.9e-71 239.7 0.2 2.2e-71 239.6 0.2 1.0 1 0 0 1 1 1 1 CutC family AP_endonuc_2 PF01261.24 EGR31171.1 - 0.042 13.3 0.0 0.11 12.0 0.0 1.6 1 1 0 1 1 1 0 Xylose isomerase-like TIM barrel Pkinase PF00069.25 EGR31172.1 - 1.5e-28 99.9 0.7 1.9e-28 99.6 0.7 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31172.1 - 1.5e-18 67.0 0.1 1.8e-18 66.8 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR31172.1 - 4.3e-05 22.5 0.0 6.9e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase DnaB_2 PF07261.11 EGR31172.1 - 0.0023 17.7 1.1 0.0023 17.7 1.1 2.1 2 0 0 2 2 2 1 Replication initiation and membrane attachment APH PF01636.23 EGR31172.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Cullin PF00888.22 EGR31174.1 - 5.4e-16 58.3 2.6 7.1e-16 58.0 2.6 1.1 1 0 0 1 1 1 1 Cullin family RPA_C PF08784.11 EGR31174.1 - 0.1 13.2 0.0 0.27 11.9 0.0 1.7 1 0 0 1 1 1 0 Replication protein A C terminal Asn_synthase PF00733.21 EGR31175.1 - 6.2e-17 62.3 2.6 5.9e-11 42.6 0.2 3.4 2 1 1 3 3 3 2 Asparagine synthase GATase_7 PF13537.6 EGR31175.1 - 3.9e-14 52.6 0.2 1.7e-13 50.5 0.0 2.1 2 0 0 2 2 2 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGR31175.1 - 9.3e-11 42.1 0.0 1.8e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EGR31175.1 - 0.0034 16.9 0.1 0.0083 15.6 0.1 1.6 1 0 0 1 1 1 1 Aluminium induced protein ATP_bind_3 PF01171.20 EGR31175.1 - 0.0055 16.5 0.0 0.017 14.9 0.0 1.9 1 0 0 1 1 1 1 PP-loop family NAD_synthase PF02540.17 EGR31175.1 - 0.066 12.3 0.5 0.37 9.9 0.0 2.2 2 0 0 2 2 2 0 NAD synthase Mur_ligase_M PF08245.12 EGR31175.1 - 4.4 7.2 6.6 1.5 8.8 2.9 2.1 2 0 0 2 2 2 0 Mur ligase middle domain NAD_binding_1 PF00175.21 EGR31176.1 - 4.1e-16 59.6 0.0 8.8e-16 58.5 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_1 PF00667.20 EGR31176.1 - 1.1e-13 51.3 0.2 1.9e-13 50.5 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain DUF5595 PF18077.1 EGR31176.1 - 0.071 13.2 0.5 0.071 13.2 0.5 3.1 4 0 0 4 4 4 0 Domain of unknown function (DUF5595) YlqD PF11068.8 EGR31176.1 - 5.6 7.3 9.0 0.63 10.4 3.8 2.2 2 1 0 2 2 2 0 YlqD protein Topoisom_I PF01028.20 EGR31177.1 - 0.0037 16.5 1.0 0.0081 15.4 1.0 1.5 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core TAL_FSA PF00923.19 EGR31177.1 - 0.082 12.2 0.3 0.14 11.5 0.3 1.3 1 0 0 1 1 1 0 Transaldolase/Fructose-6-phosphate aldolase Peptidase_M20 PF01546.28 EGR31178.1 - 3.4e-14 53.1 0.0 5.2e-14 52.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGR31178.1 - 7.8e-11 41.9 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain PI3_PI4_kinase PF00454.27 EGR31180.1 - 3.7e-46 158.0 0.4 3.7e-46 158.0 0.4 4.6 5 0 0 5 5 5 1 Phosphatidylinositol 3- and 4-kinase NUC194 PF08163.12 EGR31180.1 - 2.7e-39 135.2 23.4 2.7e-39 135.2 23.4 4.6 4 1 0 4 4 4 1 NUC194 domain FATC PF02260.20 EGR31180.1 - 3.3e-13 49.2 0.2 7.9e-13 48.0 0.2 1.7 1 0 0 1 1 1 1 FATC domain Vac14_Fab1_bd PF12755.7 EGR31180.1 - 0.011 16.3 1.7 2.1 9.0 0.0 4.8 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Ras PF00071.22 EGR31181.1 - 4.3e-48 163.0 3.4 5e-48 162.8 3.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR31181.1 - 2.5e-28 98.7 0.8 4.1e-28 98.0 0.8 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR31181.1 - 4.9e-15 55.4 1.1 6e-15 55.1 1.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGR31181.1 - 0.0003 20.4 0.3 0.00048 19.7 0.3 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RIH_assoc PF08454.11 EGR31182.1 - 7.3e-31 106.0 2.6 7.3e-31 106.0 2.6 11.7 8 4 1 9 9 9 1 RyR and IP3R Homology associated Thioredoxin PF00085.20 EGR31182.1 - 8.7e-20 70.6 0.2 4.1e-19 68.5 0.2 2.2 1 0 0 1 1 1 1 Thioredoxin MIR PF02815.19 EGR31182.1 - 4.3e-10 39.8 1.0 1.2e-08 35.0 0.0 3.5 2 1 0 2 2 2 1 MIR domain Thioredoxin_2 PF13098.6 EGR31182.1 - 4.5e-06 27.1 0.3 3.4e-05 24.3 0.3 2.7 1 0 0 1 1 1 1 Thioredoxin-like domain PAS_9 PF13426.7 EGR31183.1 - 0.0053 17.0 0.2 0.0053 17.0 0.2 4.1 3 0 0 3 3 3 1 PAS domain Na_H_Exchanger PF00999.21 EGR31184.1 - 2.6e-41 141.7 18.2 3.8e-41 141.2 18.2 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family cNMP_binding PF00027.29 EGR31184.1 - 0.0017 18.4 0.0 0.0044 17.1 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Cbl_N PF02262.16 EGR31184.1 - 2.2 8.3 10.6 0.38 10.8 1.6 3.4 2 1 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 Pkinase PF00069.25 EGR31185.1 - 2.3e-58 197.7 5.6 2.8e-58 197.4 5.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31185.1 - 9.1e-36 123.5 1.1 1.2e-35 123.1 1.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31185.1 - 7e-06 25.6 2.0 8.9e-06 25.2 2.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR31185.1 - 2.8e-05 23.1 0.1 3.1e-05 22.9 0.1 1.3 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR31185.1 - 0.00035 20.0 0.5 0.00052 19.4 0.5 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGR31185.1 - 0.003 17.2 1.5 0.0045 16.6 0.8 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EGR31185.1 - 0.0044 17.0 0.0 0.0062 16.5 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4215 PF13948.6 EGR31186.1 - 5.9e-31 106.7 280.9 2.3e-09 37.6 12.5 16.3 16 1 0 16 16 16 9 Domain of unknown function (DUF4215) Furin-like_2 PF15913.5 EGR31186.1 - 2e-05 24.7 25.1 2e-05 24.7 25.1 9.3 1 1 8 10 10 10 3 Furin-like repeat, cysteine-rich UCH PF00443.29 EGR31187.1 - 2.3e-45 155.1 5.1 2.8e-45 154.8 5.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR31187.1 - 3.1e-21 76.3 3.9 2e-20 73.6 3.9 1.9 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Receptor_2B4 PF11465.8 EGR31187.1 - 0.06 13.6 0.1 0.13 12.4 0.1 1.5 1 0 0 1 1 1 0 Natural killer cell receptor 2B4 Pkinase PF00069.25 EGR31189.1 - 5.4e-66 222.7 0.6 5.4e-66 222.7 0.6 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31189.1 - 2.1e-30 105.9 2.6 2.4e-24 86.0 2.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR31189.1 - 1.8e-06 27.2 7.6 2.8e-06 26.6 7.6 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGR31189.1 - 0.00029 20.3 0.5 0.00029 20.3 0.5 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGR31189.1 - 0.0021 17.7 0.4 0.0021 17.7 0.4 2.7 3 0 0 3 3 3 1 RIO1 family Kinase-like PF14531.6 EGR31189.1 - 0.0027 17.1 1.7 0.13 11.6 0.1 2.6 2 1 0 2 2 2 1 Kinase-like APH PF01636.23 EGR31189.1 - 0.015 15.3 0.1 0.23 11.3 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family CotJB PF12652.7 EGR31189.1 - 0.22 11.8 3.4 1.9 8.8 0.7 2.8 2 0 0 2 2 2 0 CotJB protein ESM4 PF15952.5 EGR31189.1 - 1.4 9.3 8.4 3 8.3 8.4 1.6 1 0 0 1 1 1 0 Enhancer of split M4 family Atg14 PF10186.9 EGR31189.1 - 1.7 7.7 9.5 3.2 6.8 9.5 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 LTXXQ PF07813.12 EGR31189.1 - 2.4 8.9 11.8 1.3 9.8 8.8 2.0 1 1 1 2 2 2 0 LTXXQ motif family protein TMPIT PF07851.13 EGR31189.1 - 7 5.8 9.2 11 5.1 9.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein Pkinase PF00069.25 EGR31190.1 - 2.9e-73 246.5 0.3 5.9e-73 245.5 0.3 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31190.1 - 4.6e-39 134.2 0.0 8.3e-39 133.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EGR31190.1 - 4.7e-36 122.8 5.0 6e-19 68.0 0.4 2.8 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 EGR31190.1 - 1.3e-07 31.3 0.0 4.5e-06 26.2 0.0 2.6 1 1 1 2 2 2 1 Kinase-like DUF4524 PF15025.6 EGR31190.1 - 0.011 15.5 0.1 0.13 12.0 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4524) DUF3035 PF11233.8 EGR31190.1 - 4.1 7.7 6.6 0.36 11.1 1.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3035) Plk4_PB2 PF18409.1 EGR31190.1 - 8 7.2 11.3 1.1 10.0 1.3 3.5 3 0 0 3 3 3 0 Polo-like Kinase 4 Polo Box 2 HEAT PF02985.22 EGR31191.1 - 1.3e-16 59.2 0.0 0.089 13.1 0.0 9.1 9 0 0 9 9 8 3 HEAT repeat HEAT_2 PF13646.6 EGR31191.1 - 3e-13 50.0 0.0 0.0024 18.2 0.0 6.6 4 2 2 6 6 6 2 HEAT repeats Importin_rep_4 PF18808.1 EGR31191.1 - 1.4e-11 44.5 7.7 3.4e-10 40.1 0.1 4.9 4 2 1 5 5 5 1 Importin repeat HEAT_EZ PF13513.6 EGR31191.1 - 1.4e-10 41.5 0.0 0.045 14.3 0.0 6.4 7 0 0 7 7 6 2 HEAT-like repeat IBN_N PF03810.19 EGR31191.1 - 3.6e-05 23.6 6.6 0.00026 20.8 3.3 3.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain CLASP_N PF12348.8 EGR31191.1 - 0.00057 19.5 10.6 0.31 10.6 1.3 5.5 6 2 1 7 7 7 2 CLASP N terminal UME PF08064.13 EGR31191.1 - 0.001 18.9 8.2 4.2 7.3 0.0 7.1 7 2 2 9 9 9 1 UME (NUC010) domain Proteasom_PSMB PF10508.9 EGR31191.1 - 0.0052 15.4 0.0 0.0052 15.4 0.0 3.7 2 1 4 6 6 6 1 Proteasome non-ATPase 26S subunit Vac14_Fab1_bd PF12755.7 EGR31191.1 - 0.029 15.0 9.1 2.1 9.0 0.0 6.2 5 2 3 8 8 6 0 Vacuolar 14 Fab1-binding region Arm PF00514.23 EGR31191.1 - 0.045 13.8 0.0 2.7 8.2 0.0 3.9 5 0 0 5 5 4 0 Armadillo/beta-catenin-like repeat Eisosome1 PF12757.7 EGR31191.1 - 0.067 13.5 1.8 0.18 12.1 1.8 1.7 1 0 0 1 1 1 0 Eisosome protein 1 Cnd1 PF12717.7 EGR31191.1 - 0.099 12.7 17.1 0.37 10.8 0.0 5.2 5 1 0 5 5 5 0 non-SMC mitotic condensation complex subunit 1 Cohesin_HEAT PF12765.7 EGR31191.1 - 0.92 9.9 5.4 3.6 8.0 0.0 3.8 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion MMS19_N PF14500.6 EGR31191.1 - 1.1 8.8 5.6 15 5.1 0.0 4.3 5 1 1 6 6 6 0 Dos2-interacting transcription regulator of RNA-Pol-II UCH PF00443.29 EGR31191.1 - 8.4 5.8 9.3 3.5e+03 -2.8 9.3 3.7 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase GCD14 PF08704.10 EGR31192.1 - 1.8e-72 243.9 0.0 2.6e-72 243.4 0.0 1.2 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 EGR31192.1 - 1.5e-07 31.3 0.2 2.3e-07 30.7 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.17 EGR31192.1 - 3.8e-05 22.9 0.0 6.3e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Fibrillarin PCMT PF01135.19 EGR31192.1 - 0.0011 18.8 0.0 0.0028 17.4 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Ubie_methyltran PF01209.18 EGR31192.1 - 0.0012 18.2 0.0 0.0021 17.4 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EGR31192.1 - 0.018 15.7 0.0 0.04 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGR31192.1 - 0.027 15.1 0.0 0.055 14.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain RrnaAD PF00398.20 EGR31192.1 - 0.028 13.5 0.4 0.071 12.2 0.0 1.7 2 0 0 2 2 2 0 Ribosomal RNA adenine dimethylase Methyltr_RsmB-F PF01189.17 EGR31192.1 - 0.042 13.5 0.0 0.5 10.0 0.0 2.1 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F Ras PF00071.22 EGR31194.1 - 5.8e-58 195.1 1.8 8.2e-58 194.6 1.8 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR31194.1 - 1.5e-31 109.1 2.9 2.1e-31 108.7 0.2 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR31194.1 - 9.1e-16 57.8 0.3 1.2e-15 57.4 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGR31194.1 - 1.1e-05 25.0 2.0 2.1e-05 24.0 1.9 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGR31194.1 - 3.3e-05 23.9 1.0 6.8e-05 22.9 0.1 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGR31194.1 - 0.0001 21.9 0.2 0.00034 20.2 0.2 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGR31194.1 - 0.0017 18.3 1.1 0.48 10.3 0.2 2.4 1 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EGR31194.1 - 0.0044 16.6 0.3 0.068 12.7 0.3 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B PNP_UDP_1 PF01048.20 EGR31195.1 - 6.1e-51 172.9 0.1 6.8e-51 172.8 0.1 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Kazal_1 PF00050.21 EGR31196.1 - 9.7e-05 22.3 36.7 0.0001 22.3 2.8 5.5 3 2 1 4 4 4 3 Kazal-type serine protease inhibitor domain zf-RING_6 PF14835.6 EGR31196.1 - 0.03 14.2 0.5 0.15 11.9 0.5 2.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Di19_C PF14571.6 EGR31196.1 - 0.053 14.1 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Stress-induced protein Di19, C-terminal MgrB PF13998.6 EGR31196.1 - 0.17 11.8 2.7 0.74 9.7 0.1 3.4 3 0 0 3 3 3 0 MgrB protein DAP3 PF10236.9 EGR31197.1 - 3.8e-27 95.3 0.4 2.1e-16 60.0 0.1 2.6 2 1 1 3 3 3 2 Mitochondrial ribosomal death-associated protein 3 LON_substr_bdg PF02190.16 EGR31197.1 - 0.0024 17.8 0.2 0.0063 16.4 0.2 1.8 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA_22 PF13401.6 EGR31197.1 - 0.0027 18.0 0.0 1.7 9.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain DUF3452 PF11934.8 EGR31197.1 - 0.056 13.0 4.3 0.069 12.7 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3452) STAT_int PF02865.17 EGR31197.1 - 0.076 13.5 0.5 0.22 12.0 0.5 1.8 1 0 0 1 1 1 0 STAT protein, protein interaction domain Lon_C PF05362.13 EGR31198.1 - 2.4e-43 148.1 0.2 3.5e-42 144.3 0.0 2.2 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 EGR31198.1 - 2.5e-15 57.1 0.0 5.2e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGR31198.1 - 8.1e-08 32.4 0.0 2.6e-07 30.7 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 EGR31198.1 - 3.7e-07 30.0 0.0 7.7e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_2 PF07724.14 EGR31198.1 - 6.9e-07 29.5 0.0 6.9e-07 29.5 0.0 2.4 3 1 0 3 3 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGR31198.1 - 1.3e-05 25.7 1.7 9e-05 22.9 0.0 2.5 2 1 1 3 3 2 1 AAA ATPase domain TIP49 PF06068.13 EGR31198.1 - 3.7e-05 23.1 0.1 7.4e-05 22.1 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_11 PF13086.6 EGR31198.1 - 9.5e-05 22.3 0.9 0.002 17.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGR31198.1 - 0.00013 22.2 0.4 0.018 15.3 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGR31198.1 - 0.00037 20.3 1.7 0.00075 19.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EGR31198.1 - 0.00052 19.8 0.1 0.0016 18.2 0.1 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EGR31198.1 - 0.00086 19.7 0.1 0.0035 17.7 0.1 2.1 1 1 0 1 1 1 1 RNA helicase AAA_14 PF13173.6 EGR31198.1 - 0.0014 18.6 4.9 0.0014 18.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EGR31198.1 - 0.0018 18.0 0.0 0.0038 17.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 EGR31198.1 - 0.0031 18.1 0.1 0.012 16.2 0.0 2.0 2 0 0 2 2 1 1 AAA domain Zeta_toxin PF06414.12 EGR31198.1 - 0.0047 16.2 0.1 0.011 15.0 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.11 EGR31198.1 - 0.0049 16.7 0.0 0.0095 15.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGR31198.1 - 0.01 15.4 0.0 0.026 14.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region NACHT PF05729.12 EGR31198.1 - 0.013 15.5 0.1 0.096 12.6 0.1 2.3 1 1 0 1 1 1 0 NACHT domain TsaE PF02367.17 EGR31198.1 - 0.015 15.3 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EGR31198.1 - 0.015 14.7 0.0 0.04 13.3 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 EGR31198.1 - 0.016 15.1 1.0 0.56 10.1 0.0 2.7 2 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EGR31198.1 - 0.017 15.5 0.2 0.066 13.5 0.1 2.1 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 EGR31198.1 - 0.021 15.0 0.6 0.069 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGR31198.1 - 0.022 14.5 1.1 0.076 12.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EGR31198.1 - 0.034 13.8 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain APS_kinase PF01583.20 EGR31198.1 - 0.039 13.8 0.0 0.085 12.8 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase NTPase_1 PF03266.15 EGR31198.1 - 0.043 13.7 0.1 0.19 11.6 0.0 2.1 1 1 1 2 2 2 0 NTPase ABC_tran PF00005.27 EGR31198.1 - 0.044 14.3 0.5 0.51 10.8 0.0 2.3 2 0 0 2 2 2 0 ABC transporter NB-ARC PF00931.22 EGR31198.1 - 0.06 12.5 1.3 0.068 12.4 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain DNA_pol3_delta2 PF13177.6 EGR31198.1 - 0.069 12.9 2.4 5.9 6.7 0.1 2.8 3 0 0 3 3 3 0 DNA polymerase III, delta subunit Septin PF00735.18 EGR31198.1 - 0.15 11.3 5.4 0.045 13.0 0.8 2.3 3 0 0 3 3 3 0 Septin SRP9-21 PF05486.12 EGR31198.1 - 0.17 12.3 1.8 0.36 11.2 1.8 1.5 1 0 0 1 1 1 0 Signal recognition particle 9 kDa protein (SRP9) Cytidylate_kin PF02224.18 EGR31198.1 - 0.25 11.1 1.1 0.3 10.8 0.1 1.7 2 0 0 2 2 1 0 Cytidylate kinase RIH_assoc PF08454.11 EGR31200.1 - 4.9e-14 52.0 11.1 4.9e-14 52.0 11.1 8.4 4 2 1 6 6 6 1 RyR and IP3R Homology associated MORN PF02493.20 EGR31201.1 - 1.4e-67 219.7 113.4 3.3e-08 33.0 1.6 15.0 15 0 0 15 15 15 14 MORN repeat Metallophos_2 PF12850.7 EGR31202.1 - 4e-12 46.6 0.0 2.7e-05 24.4 0.0 2.1 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EGR31202.1 - 0.0017 18.9 0.1 0.0021 18.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Kelch_1 PF01344.25 EGR31203.1 - 4.6e-50 167.0 4.9 8.9e-12 44.4 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EGR31203.1 - 1.3e-33 114.1 4.2 2e-07 31.1 0.0 6.3 4 1 2 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGR31203.1 - 7.8e-28 96.2 3.2 1.7e-05 24.7 0.0 6.2 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 EGR31203.1 - 1.3e-25 89.1 1.3 2.2e-07 31.0 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 EGR31203.1 - 3.3e-16 58.5 0.2 0.12 12.4 0.0 6.1 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.6 EGR31203.1 - 7.5e-14 51.3 9.3 0.0088 16.0 0.1 6.4 6 0 0 6 6 6 3 Kelch motif Rad60-SLD PF11976.8 EGR31203.1 - 0.13 12.1 3.2 0.5 10.2 3.2 2.1 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like LD_cluster2 PF18163.1 EGR31203.1 - 0.57 9.7 0.0 0.57 9.7 0.0 2.7 2 1 1 3 3 3 0 SLOG cluster2 Ribosomal_L13 PF00572.18 EGR31204.1 - 7.1e-10 39.2 0.1 2.8e-07 30.8 0.0 2.9 1 1 1 2 2 2 1 Ribosomal protein L13 GGACT PF06094.12 EGR31204.1 - 0.015 15.9 0.0 0.089 13.4 0.0 2.1 1 1 1 2 2 2 0 Gamma-glutamyl cyclotransferase, AIG2-like WSD PF15613.6 EGR31205.1 - 0.0031 17.9 1.4 0.0066 16.9 1.4 1.6 1 1 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Peptidase_C2 PF00648.21 EGR31206.1 - 3.6e-69 233.1 1.2 6.5e-69 232.2 1.2 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Calpain_III PF01067.22 EGR31206.1 - 4.7e-24 85.3 15.2 4.4e-08 33.5 0.5 4.4 3 1 0 3 3 3 3 Calpain large subunit, domain III E1-E2_ATPase PF00122.20 EGR31207.1 - 5.7e-21 74.8 0.0 5.7e-21 74.8 0.0 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_N PF00690.26 EGR31207.1 - 4.1e-05 23.2 0.4 0.00011 21.8 0.4 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGR31207.1 - 0.00035 20.6 1.8 0.0021 18.1 1.8 2.4 1 1 0 1 1 1 1 Cation transport ATPase (P-type) MKLP1_Arf_bdg PF16540.5 EGR31207.1 - 0.074 13.1 1.7 0.33 11.0 1.7 2.1 1 0 0 1 1 1 0 Arf6-interacting domain of mitotic kinesin-like protein 1 BBS2_Mid PF14783.6 EGR31208.1 - 0.0069 16.4 1.6 0.049 13.7 0.1 3.0 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region DUF1843 PF08898.10 EGR31208.1 - 0.023 15.2 0.8 3.1 8.4 0.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) Phage_int_SAM_3 PF14659.6 EGR31208.1 - 2.5 8.4 8.4 1.5 9.2 0.1 3.9 4 0 0 4 4 4 0 Phage integrase, N-terminal SAM-like domain EF-hand_7 PF13499.6 EGR31209.1 - 9.3e-11 42.0 1.5 1.8e-10 41.1 0.1 2.1 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGR31209.1 - 1.1e-09 37.1 0.8 1.2e-05 24.5 0.1 3.1 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGR31209.1 - 5.6e-07 28.8 1.2 0.005 16.3 0.4 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGR31209.1 - 1.4e-06 27.8 3.0 0.047 13.6 0.0 3.1 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EGR31209.1 - 1.4e-06 28.0 0.1 1.4e-06 28.0 0.1 2.1 2 1 1 3 3 3 2 EF-hand domain pair Secretin_N PF03958.17 EGR31209.1 - 0.09 13.2 0.2 0.23 11.9 0.0 1.8 2 1 0 2 2 2 0 Bacterial type II/III secretion system short domain Proteasome PF00227.26 EGR31210.1 - 1.5e-54 184.4 0.0 2.3e-54 183.8 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGR31210.1 - 1.2e-10 40.9 0.0 2.6e-10 39.8 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Ribosomal_L50 PF10501.9 EGR31210.1 - 2 8.6 10.5 2.3 8.4 1.0 2.8 2 0 0 2 2 2 0 Ribosomal subunit 39S Ribosomal_L5 PF00281.19 EGR31211.1 - 4e-19 68.7 0.0 7.8e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 EGR31211.1 - 1.6e-18 66.7 0.3 5.4e-17 61.8 0.3 2.4 1 1 0 1 1 1 1 ribosomal L5P family C-terminus HTH_ABP1_N PF18107.1 EGR31211.1 - 0.001 18.7 1.2 0.0031 17.2 0.6 2.0 2 0 0 2 2 2 1 Fission yeast centromere protein N-terminal domain Peptidase_C1 PF00112.23 EGR31212.1 - 1.6e-69 234.3 4.0 1.9e-69 234.1 4.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGR31212.1 - 7.4e-05 21.7 2.6 0.011 14.5 0.3 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Peptidase_C39_2 PF13529.6 EGR31212.1 - 0.058 14.0 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 Peptidase_C39 like family PAS PF00989.25 EGR31213.1 - 1.7e-05 24.8 0.1 8.2e-05 22.6 0.1 2.3 1 0 0 1 1 1 1 PAS fold RepA_C PF04796.12 EGR31213.1 - 0.013 15.5 2.6 0.056 13.5 0.1 2.8 2 0 0 2 2 2 0 Plasmid encoded RepA protein AMMECR1 PF01871.17 EGR31214.1 - 1.5e-46 158.0 0.0 1.7e-46 157.8 0.0 1.0 1 0 0 1 1 1 1 AMMECR1 Pkinase PF00069.25 EGR31215.1 - 8.3e-60 202.4 4.6 1.4e-59 201.7 4.6 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31215.1 - 6.5e-33 114.1 1.3 1e-32 113.5 1.3 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31215.1 - 6.7e-08 32.2 0.5 1.6e-07 30.9 0.1 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR31215.1 - 0.017 14.5 1.0 0.032 13.6 1.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR31215.1 - 0.022 13.6 0.4 0.047 12.5 0.4 1.5 1 1 0 1 1 1 0 Fungal protein kinase zf-UBR PF02207.20 EGR31216.1 - 1.1e-12 47.9 12.1 1.6e-12 47.4 12.1 1.3 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Cas9_C PF18525.1 EGR31216.1 - 0.043 14.0 0.0 0.05 13.8 0.0 1.2 1 0 0 1 1 1 0 Cas9 C-terminal domain Copine PF07002.16 EGR31217.1 - 1e-67 227.8 0.0 1.5e-67 227.2 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 EGR31217.1 - 1.8e-07 31.4 0.5 6.3e-06 26.4 0.1 2.4 2 0 0 2 2 2 1 C2 domain vWA-TerF-like PF10138.9 EGR31217.1 - 0.00098 19.3 0.0 0.0026 17.9 0.0 1.7 1 0 0 1 1 1 1 vWA found in TerF C terminus SIR2 PF02146.17 EGR31218.1 - 9.5 6.1 9.7 2 8.3 5.5 1.9 1 1 0 1 1 1 0 Sir2 family DUF693 PF05113.13 EGR31219.1 - 0.035 13.4 0.2 0.049 12.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF693) Mito_carr PF00153.27 EGR31220.1 - 6.5e-14 51.6 0.4 3e-07 30.3 0.0 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein Ribosomal_L20 PF00453.18 EGR31221.1 - 1.3e-32 112.1 2.3 2e-32 111.4 2.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L20 Pkinase PF00069.25 EGR31222.1 - 1.2e-22 80.6 0.0 1.6e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31222.1 - 0.00019 20.8 0.0 0.00025 20.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Crystallin PF00525.18 EGR31222.1 - 0.0031 17.6 1.2 0.0039 17.3 0.1 1.7 2 0 0 2 2 2 1 Alpha crystallin A chain, N terminal EF-hand_7 PF13499.6 EGR31223.1 - 1e-15 57.9 1.0 1.3e-06 28.8 0.4 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR31223.1 - 6.7e-13 47.5 0.8 0.0016 18.2 0.0 4.1 2 2 1 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 EGR31223.1 - 1.2e-08 33.9 0.5 0.0073 15.8 0.0 3.7 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EGR31223.1 - 6.7e-05 22.7 2.6 0.029 14.2 0.1 3.6 2 2 1 3 3 3 1 EF-hand domain pair Pkinase PF00069.25 EGR31223.1 - 0.00014 21.4 0.2 0.00021 20.8 0.2 1.6 1 1 0 1 1 1 1 Protein kinase domain EF-hand_9 PF14658.6 EGR31223.1 - 0.0049 17.2 0.0 0.16 12.3 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_14 PF17959.1 EGR31223.1 - 0.025 14.9 2.9 0.57 10.6 0.2 2.3 1 1 1 2 2 2 0 EF-hand domain DUF1456 PF07308.13 EGR31223.1 - 0.03 14.7 2.6 0.37 11.2 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1456) Pkinase PF00069.25 EGR31224.1 - 6e-40 137.3 0.1 6.7e-40 137.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31224.1 - 3.7e-29 101.8 0.0 4.7e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31224.1 - 1.6e-05 24.4 0.0 2.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGR31224.1 - 0.0091 15.0 0.0 0.014 14.4 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGR31224.1 - 0.014 14.2 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Pkinase PF00069.25 EGR31225.1 - 9.8e-67 225.1 0.3 1.2e-66 224.8 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31225.1 - 8.4e-33 113.7 0.0 1.1e-32 113.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR31225.1 - 0.00021 20.2 0.0 0.00065 18.6 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGR31225.1 - 0.00034 20.0 0.1 0.0017 17.8 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGR31225.1 - 0.00038 19.5 0.2 0.00054 19.0 0.2 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EGR31225.1 - 0.031 13.3 0.0 0.055 12.5 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Guanylate_cyc PF00211.20 EGR31226.1 - 8.6e-10 38.5 0.0 1.9e-09 37.4 0.0 1.5 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain TPR_2 PF07719.17 EGR31226.1 - 0.0065 16.5 0.1 0.018 15.1 0.1 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat HECT PF00632.25 EGR31227.1 - 3e-81 273.3 17.7 3.6e-81 273.0 17.7 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Ras PF00071.22 EGR31228.1 - 7.2e-55 185.0 0.9 8.5e-55 184.8 0.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR31228.1 - 1.3e-32 112.6 0.6 1.9e-32 112.0 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR31228.1 - 2.2e-16 59.8 0.2 2.7e-16 59.5 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGR31228.1 - 6.7e-08 32.2 0.3 8.5e-08 31.8 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGR31228.1 - 1e-06 28.5 0.3 3.2e-06 26.8 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGR31228.1 - 2.3e-06 27.6 0.1 4.1e-06 26.9 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 EGR31228.1 - 0.006 16.0 0.0 0.013 14.9 0.0 1.5 2 0 0 2 2 2 1 Bacterial TniB protein AAA_24 PF13479.6 EGR31228.1 - 0.01 15.5 0.2 0.016 14.9 0.2 1.6 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGR31228.1 - 0.017 15.1 0.2 4 7.3 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase Glycos_transf_1 PF00534.20 EGR31228.1 - 0.024 14.2 0.4 0.042 13.4 0.4 1.4 1 0 0 1 1 1 0 Glycosyl transferases group 1 INSC_LBD PF16748.5 EGR31228.1 - 0.026 13.9 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Inscuteable LGN-binding domain MCM PF00493.23 EGR31228.1 - 0.027 13.6 0.1 0.083 12.0 0.0 1.9 2 1 0 2 2 2 0 MCM P-loop domain AAA_22 PF13401.6 EGR31228.1 - 0.095 13.0 0.1 0.29 11.4 0.0 2.0 1 1 1 2 2 2 0 AAA domain AAA_14 PF13173.6 EGR31228.1 - 0.23 11.5 1.6 0.72 9.9 0.0 2.1 2 1 0 2 2 2 0 AAA domain Sod_Cu PF00080.20 EGR31229.1 - 4.8e-36 124.0 0.4 6.2e-36 123.7 0.4 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Bac_A_amyl_C PF18612.1 EGR31229.1 - 0.089 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial Alpha amylase C-terminal domain NuiA PF07924.11 EGR31230.1 - 0.013 15.9 1.5 0.018 15.4 1.5 1.2 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein UDPGP PF01704.18 EGR31232.1 - 2.6e-32 112.0 23.2 1.1e-31 109.9 22.8 2.0 1 1 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase TPPII PF12580.8 EGR31232.1 - 0.014 14.8 2.5 0.027 13.9 2.5 1.4 1 0 0 1 1 1 0 Tripeptidyl peptidase II SF3a60_bindingd PF12108.8 EGR31232.1 - 0.26 11.2 0.1 0.26 11.2 0.1 2.5 3 0 0 3 3 3 0 Splicing factor SF3a60 binding domain MORN PF02493.20 EGR31233.1 - 6.7e-09 35.1 31.0 0.00051 19.8 2.2 4.5 4 0 0 4 4 4 4 MORN repeat DUF3048_C PF17479.2 EGR31233.1 - 0.00029 21.2 7.8 0.0009 19.6 0.2 2.4 2 1 1 3 3 3 2 Protein of unknown function (DUF3048) C-terminal domain Proteasome_A_N PF10584.9 EGR31233.1 - 0.081 12.6 1.8 9 6.1 0.1 3.3 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature Ribosomal_L24e PF01246.20 EGR31233.1 - 0.64 10.3 2.7 15 5.9 0.9 2.7 2 1 0 2 2 2 0 Ribosomal protein L24e MORN_2 PF07661.13 EGR31233.1 - 3.8 8.0 15.3 1.8 9.0 0.1 5.0 4 2 2 6 6 6 0 MORN repeat variant MFS_1 PF07690.16 EGR31234.1 - 8.2e-07 28.3 0.0 1.3e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Reoviridae_Vp9 PF08978.10 EGR31234.1 - 0.27 10.4 2.6 0.14 11.3 0.2 1.6 2 0 0 2 2 2 0 Reoviridae VP9 AlaDh_PNT_N PF05222.15 EGR31235.1 - 5.5e-25 88.2 0.0 1.2e-24 87.1 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Saccharop_dh_N PF04455.12 EGR31235.1 - 5.6e-11 42.7 1.5 8.5e-11 42.1 0.4 2.0 2 0 0 2 2 2 1 LOR/SDH bifunctional enzyme conserved region AlaDh_PNT_C PF01262.21 EGR31235.1 - 1.7e-06 27.5 0.0 1.6e-05 24.3 0.0 2.3 1 1 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain T-box PF00907.22 EGR31235.1 - 0.032 14.5 2.0 0.04 14.2 0.2 2.0 2 0 0 2 2 2 0 T-box L51_S25_CI-B8 PF05047.16 EGR31235.1 - 0.11 12.4 3.2 2.4 8.1 0.2 3.4 4 0 0 4 4 4 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Asp PF00026.23 EGR31236.1 - 3.9e-13 49.5 9.4 2.1e-12 47.1 3.0 2.2 2 0 0 2 2 2 2 Eukaryotic aspartyl protease VPS13_C PF16909.5 EGR31237.1 - 4.5e-46 156.9 5.3 2.4e-41 141.5 1.2 2.1 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 EGR31237.1 - 5.2e-11 42.7 0.0 2.2e-10 40.7 0.0 2.0 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain C2 PF00168.30 EGR31238.1 - 1.6e-13 50.9 0.0 2.1e-13 50.5 0.0 1.1 1 0 0 1 1 1 1 C2 domain DUF676 PF05057.14 EGR31239.1 - 2.8e-35 121.8 1.2 3.8e-35 121.4 0.8 1.4 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGR31239.1 - 1.9e-07 31.2 2.6 2.5e-07 30.8 2.6 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 EGR31239.1 - 1.4e-06 28.2 0.2 2.9e-06 27.2 0.2 1.7 1 1 0 1 1 1 1 PGAP1-like protein NuiA PF07924.11 EGR31239.1 - 0.008 16.6 0.7 0.013 15.8 0.7 1.4 1 0 0 1 1 1 1 Nuclease A inhibitor-like protein KTI12 PF08433.10 EGR31239.1 - 0.021 14.3 0.6 0.039 13.4 0.6 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AHSP PF09236.10 EGR31239.1 - 0.062 13.8 1.1 0.062 13.8 1.1 1.8 2 0 0 2 2 2 0 Alpha-haemoglobin stabilising protein Esterase PF00756.20 EGR31239.1 - 0.098 12.3 0.0 0.18 11.4 0.0 1.3 1 1 0 1 1 1 0 Putative esterase Abhydrolase_6 PF12697.7 EGR31239.1 - 0.24 12.0 0.0 0.26 11.8 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family SgrT PF15894.5 EGR31240.1 - 4.3 7.4 5.5 0.62 10.1 0.7 2.0 2 0 0 2 2 2 0 Inhibitor of glucose uptake transporter SgrT Mito_carr PF00153.27 EGR31242.1 - 3e-40 136.0 0.9 5.5e-16 58.3 0.0 4.0 3 1 1 4 4 4 4 Mitochondrial carrier protein SMP_2 PF10144.9 EGR31242.1 - 0.067 12.8 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin AAA_6 PF12774.7 EGR31243.1 - 8.4e-135 448.9 5.1 2.2e-132 441.0 0.0 4.7 4 1 1 5 5 5 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGR31243.1 - 3.3e-102 342.6 25.7 3.3e-102 342.6 25.7 5.6 3 2 0 4 4 4 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 EGR31243.1 - 8.9e-101 337.1 1.1 8.9e-101 337.1 1.1 3.9 4 0 0 4 4 3 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EGR31243.1 - 4.1e-96 321.3 1.6 4.1e-96 321.3 1.6 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EGR31243.1 - 3.6e-80 268.2 8.2 1.4e-78 263.0 6.5 5.7 6 1 0 6 6 4 2 ATP-binding dynein motor region AAA_7 PF12775.7 EGR31243.1 - 1.3e-63 213.8 0.7 1.2e-59 200.9 0.0 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGR31243.1 - 8e-61 204.6 0.2 3.3e-60 202.6 0.2 2.2 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGR31243.1 - 1.5e-42 144.5 1.6 4e-40 136.6 0.0 4.6 4 0 0 4 4 4 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EGR31243.1 - 2.1e-35 122.4 19.8 5.5e-35 121.0 19.8 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_1 PF17857.1 EGR31243.1 - 4.5e-23 81.3 3.6 5.3e-22 77.9 0.2 3.7 3 0 0 3 3 2 1 AAA+ lid domain Dynein_AAA_lid PF17852.1 EGR31243.1 - 6.8e-15 55.3 5.7 1.5e-14 54.2 0.1 3.9 4 0 0 4 4 3 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EGR31243.1 - 1.5e-13 51.0 0.1 0.0022 18.0 0.0 6.2 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA PF00004.29 EGR31243.1 - 6.3e-09 36.4 1.7 0.0058 17.1 0.0 4.3 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGR31243.1 - 0.00013 22.4 2.3 0.32 11.3 0.0 4.6 4 0 0 4 4 4 1 AAA ATPase domain T2SSE PF00437.20 EGR31243.1 - 0.00045 19.4 0.2 0.0089 15.1 0.0 2.8 3 0 0 3 3 3 1 Type II/IV secretion system protein AAA_22 PF13401.6 EGR31243.1 - 0.00054 20.3 2.2 1.6 9.0 0.0 4.9 5 0 0 5 5 4 1 AAA domain ATG16 PF08614.11 EGR31243.1 - 0.00073 19.8 6.5 0.00073 19.8 6.5 4.2 3 0 0 3 3 3 1 Autophagy protein 16 (ATG16) AAA_18 PF13238.6 EGR31243.1 - 0.0037 17.8 11.2 0.0069 16.9 0.0 5.5 7 0 0 7 7 3 1 AAA domain BRE1 PF08647.11 EGR31243.1 - 0.0037 17.3 5.6 0.0037 17.3 5.6 7.6 7 2 0 7 7 3 1 BRE1 E3 ubiquitin ligase Serum_albumin PF00273.20 EGR31243.1 - 0.015 15.1 0.2 0.06 13.1 0.2 2.0 1 0 0 1 1 1 0 Serum albumin family NTPase_1 PF03266.15 EGR31243.1 - 0.045 13.7 1.0 0.19 11.6 0.1 2.6 2 0 0 2 2 2 0 NTPase RNA_helicase PF00910.22 EGR31243.1 - 0.045 14.1 1.1 6.1 7.3 0.0 3.8 3 0 0 3 3 2 0 RNA helicase AAA_30 PF13604.6 EGR31243.1 - 0.07 12.8 0.1 15 5.3 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EGR31243.1 - 0.17 12.2 1.5 2.6 8.4 0.2 3.5 2 0 0 2 2 2 0 AAA domain DarA_N PF18788.1 EGR31243.1 - 1.1 9.4 5.0 1.3 9.1 0.1 3.1 2 0 0 2 2 2 0 Defence against restriction A N-terminal TIMELESS PF04821.14 EGR31244.1 - 1.6e-05 24.4 0.0 1.9e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Timeless protein TIMELESS_C PF05029.13 EGR31245.1 - 4.6e-05 22.8 4.4 4.6e-05 22.8 4.4 2.5 2 0 0 2 2 2 1 Timeless protein C terminal region BUD22 PF09073.10 EGR31245.1 - 0.0025 17.2 17.7 0.0025 17.2 17.7 1.9 2 0 0 2 2 2 1 BUD22 OAD_gamma PF04277.13 EGR31245.1 - 0.97 10.1 9.2 1.4 9.6 0.2 2.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Presenilin PF01080.17 EGR31245.1 - 1.5 7.5 12.8 2.3 6.9 12.8 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 EGR31245.1 - 1.7 8.7 8.3 0.98 9.4 5.6 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Drc1-Sld2 PF11719.8 EGR31245.1 - 2.1 7.8 22.3 0.057 13.0 15.8 1.6 2 0 0 2 2 2 0 DNA replication and checkpoint protein CDC27 PF09507.10 EGR31245.1 - 4.8 6.5 29.2 8.9 5.6 29.2 1.3 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF688 PF05097.12 EGR31245.1 - 6.6 5.8 14.8 17 4.4 14.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF688) Lamprin PF06403.11 EGR31246.1 - 0.65 9.9 2.6 4.9 7.1 0.3 2.2 1 1 1 2 2 2 0 Lamprin MMR_HSR1 PF01926.23 EGR31247.1 - 6.3e-17 61.7 0.3 1.9e-16 60.1 0.3 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP-bdg_M PF16360.5 EGR31247.1 - 2e-13 50.7 2.4 7.5e-13 48.9 2.4 2.1 1 1 0 1 1 1 1 GTP-binding GTPase Middle Region GTP-bdg_N PF13167.6 EGR31247.1 - 9.9e-11 42.2 1.2 3.6e-06 27.6 0.1 3.3 3 0 0 3 3 2 2 GTP-binding GTPase N-terminal AIG1 PF04548.16 EGR31247.1 - 5e-06 26.0 0.5 1.3e-05 24.7 0.5 1.7 1 0 0 1 1 1 1 AIG1 family GTP_EFTU PF00009.27 EGR31247.1 - 0.002 17.7 1.6 0.88 9.1 0.3 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EGR31247.1 - 0.0043 17.1 7.9 0.011 15.8 0.1 3.1 2 1 1 3 3 3 1 Dynamin family MMR_HSR1_Xtn PF16897.5 EGR31247.1 - 0.017 15.2 0.3 0.061 13.3 0.3 2.0 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 EGR31247.1 - 0.035 14.0 4.0 0.079 12.9 0.3 2.5 2 0 0 2 2 2 0 RsgA GTPase RNA_helicase PF00910.22 EGR31247.1 - 0.038 14.4 0.0 0.19 12.2 0.0 2.4 1 1 0 1 1 1 0 RNA helicase FeoB_N PF02421.18 EGR31247.1 - 0.097 12.2 1.4 0.25 10.9 1.4 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Roc PF08477.13 EGR31247.1 - 0.26 11.5 6.4 0.087 13.0 0.5 3.3 4 1 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase BOP1NT PF08145.12 EGR31248.1 - 2.3e-57 194.9 12.1 2.3e-57 194.9 12.1 1.9 2 1 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.32 EGR31248.1 - 1.2e-22 79.7 1.5 2e-05 25.2 0.2 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR31248.1 - 2.1e-07 31.1 0.1 0.005 17.1 0.0 4.3 2 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain HPS3_N PF14761.6 EGR31248.1 - 0.0076 15.8 0.4 27 4.2 0.0 4.0 3 1 1 4 4 4 1 Hermansky-Pudlak syndrome 3 PQQ_2 PF13360.6 EGR31248.1 - 0.024 14.2 0.0 0.051 13.1 0.0 1.5 2 0 0 2 2 2 0 PQQ-like domain JmjC PF02373.22 EGR31249.1 - 2.3e-18 66.7 0.1 2.3e-18 66.7 0.1 2.7 3 0 0 3 3 3 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 EGR31249.1 - 7.8e-16 58.6 2.4 9.5e-16 58.3 0.3 2.2 2 1 0 2 2 2 1 Cupin-like domain GPI PF06560.11 EGR31249.1 - 0.00078 18.8 0.1 0.13 11.5 0.0 2.6 2 0 0 2 2 2 2 Glucose-6-phosphate isomerase (GPI) Cupin_2 PF07883.11 EGR31249.1 - 0.017 14.9 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Cupin domain DUF1481 PF07356.12 EGR31249.1 - 0.088 12.6 3.3 0.13 12.0 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1481) E1_dh PF00676.20 EGR31250.1 - 4.5e-99 331.2 0.4 5.4e-99 330.9 0.4 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EGR31250.1 - 0.00042 19.6 0.1 0.00092 18.5 0.1 1.6 1 1 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase TPP_enzyme_C PF02775.21 EGR31250.1 - 0.0027 17.5 1.3 0.0059 16.4 1.3 1.7 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Glyco_transf_22 PF03901.17 EGR31251.1 - 6.5e-70 236.4 46.6 8e-70 236.2 46.6 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF2237 PF09996.9 EGR31252.1 - 3.7e-24 84.9 0.0 4.4e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2237) GIDA PF01134.22 EGR31253.1 - 0.0096 15.0 1.4 0.011 14.9 1.4 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A SMC_N PF02463.19 EGR31253.1 - 0.26 10.7 1.7 0.29 10.5 1.7 1.3 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain tRNA-synt_1g PF09334.11 EGR31254.1 - 1.2e-145 485.2 1.1 1.4e-145 484.9 1.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGR31254.1 - 1.1e-09 37.2 2.4 2.2e-05 22.9 0.1 3.2 3 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) C1_1 PF00130.22 EGR31254.1 - 1.2 9.1 13.3 5.5 7.0 4.9 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) EF-hand_7 PF13499.6 EGR31255.1 - 7.8e-15 55.1 22.6 1.2e-07 32.0 3.4 5.2 4 2 1 5 5 5 3 EF-hand domain pair EF-hand_6 PF13405.6 EGR31255.1 - 8.5e-13 47.1 27.7 0.00032 20.4 0.1 7.7 8 0 0 8 8 8 4 EF-hand domain EF-hand_1 PF00036.32 EGR31255.1 - 3.2e-08 32.6 25.6 7.7e-05 22.0 0.4 5.4 6 1 0 6 6 6 2 EF hand EF-hand_8 PF13833.6 EGR31255.1 - 6.2e-07 29.2 10.4 0.031 14.1 0.2 5.0 5 0 0 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 EGR31255.1 - 6.1e-05 22.3 14.6 0.0017 17.8 0.5 3.5 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 EGR31255.1 - 0.00011 22.5 0.2 0.12 12.7 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain Ion_trans PF00520.31 EGR31256.1 - 2.1e-06 27.2 3.5 2.1e-06 27.2 3.5 1.7 2 0 0 2 2 2 1 Ion transport protein GPHH PF16905.5 EGR31256.1 - 2e-05 24.3 0.0 3.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated DUF2205 PF10224.9 EGR31256.1 - 2.3 8.3 8.6 0.096 12.7 2.1 2.1 2 1 0 2 2 2 0 Short coiled-coil protein Ion_trans PF00520.31 EGR31257.1 - 1.7e-114 381.2 70.2 5.9e-58 196.0 21.1 3.2 3 0 0 3 3 3 3 Ion transport protein PKD_channel PF08016.12 EGR31257.1 - 0.25 10.0 55.7 0.12 11.0 2.8 6.0 3 2 2 5 5 5 0 Polycystin cation channel DUF4746 PF15928.5 EGR31258.1 - 1.9 7.9 14.9 2 7.7 14.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 EGR31258.1 - 2 7.1 26.4 2 7.1 26.4 1.0 1 0 0 1 1 1 0 Presenilin AIF_C PF14721.6 EGR31258.1 - 2.3 8.6 16.7 2.9 8.3 16.7 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term SpoIIP PF07454.11 EGR31258.1 - 2.4 7.5 28.0 2.6 7.4 28.0 1.0 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Paf1 PF03985.13 EGR31258.1 - 2.7 6.9 24.5 2.8 6.9 24.5 1.0 1 0 0 1 1 1 0 Paf1 RR_TM4-6 PF06459.12 EGR31258.1 - 2.9 7.6 22.7 2.9 7.7 22.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pex14_N PF04695.13 EGR31258.1 - 3.7 8.2 39.3 4 8.1 39.3 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RPA43_OB PF17875.1 EGR31258.1 - 3.8 8.2 16.7 5.1 7.8 16.7 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I PRC2_HTH_1 PF18118.1 EGR31258.1 - 3.8 8.4 14.6 5.2 7.9 14.6 1.3 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain CLN3 PF02487.17 EGR31258.1 - 4.2 6.3 21.0 4.7 6.1 21.0 1.0 1 0 0 1 1 1 0 CLN3 protein Tfb4 PF03850.14 EGR31258.1 - 4.4 6.7 18.4 5.4 6.4 18.4 1.0 1 0 0 1 1 1 0 Transcription factor Tfb4 CPSF100_C PF13299.6 EGR31258.1 - 5.1 7.3 18.6 5.5 7.2 18.6 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 EGR31258.1 - 5.3 5.2 19.1 5.2 5.2 19.1 1.0 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.17 EGR31258.1 - 5.4 7.1 21.5 5.7 7.0 21.5 1.1 1 0 0 1 1 1 0 DDHD domain Cellulose_synt PF03552.14 EGR31258.1 - 5.5 5.3 11.4 5.7 5.3 11.4 1.0 1 0 0 1 1 1 0 Cellulose synthase Gti1_Pac2 PF09729.9 EGR31258.1 - 5.7 7.0 20.9 6.2 6.9 20.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF913 PF06025.12 EGR31258.1 - 6.2 5.7 15.6 6.1 5.7 15.6 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF5308 PF17233.2 EGR31258.1 - 6.8 6.9 21.5 8.8 6.5 21.5 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5308) CCDC53 PF10152.9 EGR31258.1 - 7.4 7.0 23.7 7.9 6.9 23.7 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex GNAT_acetyltr_2 PF13718.6 EGR31258.1 - 7.6 5.9 15.6 8.8 5.7 15.6 1.1 1 0 0 1 1 1 0 GNAT acetyltransferase 2 MCD PF05292.11 EGR31258.1 - 7.8 6.0 13.9 8.6 5.8 13.9 1.0 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain Band_3_cyto PF07565.13 EGR31258.1 - 8.6 6.1 24.4 8.8 6.0 24.4 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2828 PF11443.8 EGR31258.1 - 8.6 4.3 23.0 8.7 4.3 23.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) zf-C2H2_2 PF12756.7 EGR31259.1 - 2.3e-23 82.4 7.5 2.3e-23 82.4 7.5 2.1 2 1 0 2 2 2 1 C2H2 type zinc-finger (2 copies) Histone PF00125.24 EGR31260.1 - 3.1e-18 66.4 2.9 3.8e-18 66.1 2.9 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGR31260.1 - 1.9e-06 28.1 0.1 3.8e-06 27.1 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone AD PF09793.9 EGR31260.1 - 0.0066 16.6 0.5 0.011 15.8 0.5 1.3 1 0 0 1 1 1 1 Anticodon-binding domain RP-C PF03428.13 EGR31260.1 - 0.017 14.8 0.3 0.026 14.2 0.3 1.2 1 0 0 1 1 1 0 Replication protein C N-terminal domain TFIID_20kDa PF03847.13 EGR31260.1 - 0.025 15.0 0.1 0.041 14.4 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A TAF PF02969.17 EGR31260.1 - 0.11 12.7 0.1 0.11 12.7 0.1 1.8 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) Arm_3 PF16186.5 EGR31260.1 - 0.13 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Atypical Arm repeat AAA PF00004.29 EGR31261.1 - 3.7e-17 63.0 0.0 1.4e-16 61.1 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGR31261.1 - 0.0069 16.7 0.0 0.17 12.2 0.0 3.2 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGR31261.1 - 0.025 14.3 0.0 0.09 12.5 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein RsgA_GTPase PF03193.16 EGR31261.1 - 0.035 14.0 0.0 0.11 12.3 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 EGR31261.1 - 0.042 13.4 0.0 0.15 11.6 0.0 2.0 1 0 0 1 1 1 0 P-loop containing dynein motor region IQ PF00612.27 EGR31261.1 - 0.079 12.8 0.9 0.3 11.0 0.1 2.3 2 0 0 2 2 2 0 IQ calmodulin-binding motif ABC_tran PF00005.27 EGR31261.1 - 1.6 9.2 0.0 1.6 9.2 0.0 3.6 3 1 0 3 3 3 0 ABC transporter Glu_cyclase_2 PF05096.12 EGR31262.1 - 1e-52 179.1 2.0 1.2e-52 178.9 2.0 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase Ribonuc_red_lgC PF02867.15 EGR31263.1 - 2.1e-188 627.1 0.8 5.2e-188 625.8 0.1 1.8 2 0 0 2 2 2 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EGR31263.1 - 1.7e-21 76.0 0.1 8.3e-21 73.8 0.0 2.2 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EGR31263.1 - 0.00048 20.7 0.1 0.0018 18.8 0.0 2.1 2 0 0 2 2 2 1 ATP cone domain Proteasome PF00227.26 EGR31264.1 - 2.7e-45 154.2 0.7 3.1e-45 154.0 0.7 1.0 1 0 0 1 1 1 1 Proteasome subunit PARP_reg PF02877.14 EGR31265.1 - 1.6e-32 112.4 5.9 1.6e-32 112.4 5.9 2.9 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EGR31265.1 - 1.7e-19 69.6 2.7 1.7e-19 69.6 2.7 2.3 2 0 0 2 2 2 1 WGR domain Peptidase_M48 PF01435.18 EGR31269.1 - 8.4e-39 133.4 0.0 1.5e-38 132.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M48_N PF16491.5 EGR31269.1 - 5.4e-31 107.9 15.0 5.4e-31 107.9 15.0 2.1 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M56 PF05569.11 EGR31269.1 - 0.016 14.4 0.7 0.023 13.9 0.7 1.3 1 0 0 1 1 1 0 BlaR1 peptidase M56 SprT-like PF10263.9 EGR31269.1 - 0.031 14.2 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 SprT-like family TraG_N PF07916.11 EGR31269.1 - 0.099 11.5 0.6 0.17 10.7 0.6 1.3 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF4492 PF14899.6 EGR31269.1 - 0.11 12.5 11.6 0.11 12.4 3.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4492) EphA2_TM PF14575.6 EGR31270.1 - 5.3 8.0 7.2 8.5 7.3 5.9 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain VPS13_C PF16909.5 EGR31272.1 - 9.6e-59 198.1 9.1 7e-54 182.3 0.4 3.1 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 EGR31272.1 - 1.2e-11 44.8 0.0 8.4e-11 42.1 0.0 2.2 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain JAB PF01398.21 EGR31273.1 - 4.6e-33 113.7 1.9 1.7e-32 111.8 0.0 2.5 3 0 0 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EGR31273.1 - 1e-09 38.8 2.5 2.5e-09 37.5 1.4 2.0 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EGR31273.1 - 3.8e-08 33.1 0.0 6.4e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Nicastrin PF05450.15 EGR31273.1 - 0.038 13.4 1.1 0.079 12.4 1.1 1.5 1 0 0 1 1 1 0 Nicastrin UPF0172 PF03665.13 EGR31273.1 - 0.06 13.4 1.7 0.31 11.1 1.2 2.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0172) Pkinase PF00069.25 EGR31274.1 - 1.3e-08 34.6 0.2 3.4e-08 33.2 0.2 1.6 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EGR31274.1 - 0.0013 18.1 0.2 0.011 15.1 0.1 2.1 1 1 0 1 1 1 1 Kinase-like Pkinase_Tyr PF07714.17 EGR31274.1 - 0.021 14.1 0.0 0.049 12.9 0.0 1.6 1 1 0 1 1 1 0 Protein tyrosine kinase Cytadhesin_P30 PF07271.11 EGR31274.1 - 4.6 6.7 6.4 1.3 8.6 2.3 1.9 1 1 1 2 2 2 0 Cytadhesin P30/P32 Pkinase PF00069.25 EGR31275.1 - 2.6e-57 194.2 1.8 2.6e-57 194.2 1.8 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31275.1 - 1e-41 143.0 4.7 1.1e-41 142.9 0.1 3.0 3 0 0 3 3 3 1 Protein tyrosine kinase HEAT PF02985.22 EGR31275.1 - 3.7e-12 45.4 0.4 0.16 12.3 0.4 6.1 5 0 0 5 5 5 3 HEAT repeat HEAT_2 PF13646.6 EGR31275.1 - 1.1e-06 28.9 0.0 0.21 12.0 0.0 3.7 3 0 0 3 3 3 2 HEAT repeats HEAT_EZ PF13513.6 EGR31275.1 - 3.7e-05 24.1 0.1 7.2 7.2 0.1 4.8 4 0 0 4 4 4 1 HEAT-like repeat Pkinase_fungal PF17667.1 EGR31275.1 - 0.00021 20.2 0.5 0.00041 19.3 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Mst1_SARAH PF11629.8 EGR31275.1 - 0.018 15.1 0.5 0.049 13.7 0.5 1.8 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 LcnG-beta PF11632.8 EGR31275.1 - 0.024 14.6 0.2 0.049 13.6 0.2 1.5 1 0 0 1 1 1 0 Lactococcin G-beta Vac14_Fab1_bd PF12755.7 EGR31275.1 - 0.086 13.5 7.2 6 7.5 0.1 4.8 3 1 1 4 4 4 0 Vacuolar 14 Fab1-binding region SNase PF00565.17 EGR31276.1 - 4.6e-06 27.1 0.1 6.2e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 Staphylococcal nuclease homologue TUDOR PF00567.24 EGR31276.1 - 5.1e-05 23.3 0.1 9.4e-05 22.4 0.1 1.5 1 0 0 1 1 1 1 Tudor domain Rep_fac-A_C PF08646.10 EGR31278.1 - 5.8e-25 87.7 0.5 5.8e-25 87.7 0.5 2.5 2 0 0 2 2 2 1 Replication factor-A C terminal domain Kelch_4 PF13418.6 EGR31278.1 - 6.5e-19 67.7 0.6 1.7e-06 27.9 0.0 4.6 4 0 0 4 4 4 4 Galactose oxidase, central domain REPA_OB_2 PF16900.5 EGR31278.1 - 2.3e-16 59.5 3.1 8.3e-16 57.7 0.3 2.7 2 0 0 2 2 2 1 Replication protein A OB domain Kelch_3 PF13415.6 EGR31278.1 - 6e-16 58.3 0.0 6.8e-06 26.2 0.0 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EGR31278.1 - 1.5e-15 56.8 0.4 0.0005 20.0 0.0 4.7 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 EGR31278.1 - 3.8e-12 46.0 1.6 8e-05 22.8 0.1 4.2 4 0 0 4 4 4 2 Kelch motif Kelch_1 PF01344.25 EGR31278.1 - 4.1e-08 32.7 0.0 0.00061 19.3 0.0 2.9 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.15 EGR31278.1 - 3.5e-05 23.6 0.3 0.073 13.1 0.0 3.6 3 0 0 3 3 3 2 Kelch motif ANAPC15 PF15243.6 EGR31278.1 - 0.032 14.6 0.6 0.14 12.6 0.1 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 15 CDC24_OB3 PF17244.2 EGR31278.1 - 0.078 12.7 0.1 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 LSM PF01423.22 EGR31279.1 - 4.1e-19 68.0 1.7 5.2e-19 67.7 1.7 1.1 1 0 0 1 1 1 1 LSM domain Gemin7 PF11095.8 EGR31279.1 - 0.015 15.2 0.0 0.022 14.6 0.0 1.3 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Hfq PF17209.3 EGR31279.1 - 0.041 13.5 0.1 0.073 12.7 0.1 1.4 1 0 0 1 1 1 0 Hfq protein Tail_tube PF10618.9 EGR31279.1 - 0.089 12.7 0.1 0.22 11.4 0.1 1.7 1 1 1 2 2 2 0 Phage tail tube protein Hydrolase_4 PF12146.8 EGR31280.1 - 0.00051 19.4 0.0 0.36 10.1 0.0 2.1 1 1 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EGR31280.1 - 0.0084 15.8 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.20 EGR31280.1 - 0.038 13.6 0.0 0.65 9.6 0.0 2.0 1 1 1 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.11 EGR31280.1 - 0.12 12.3 0.1 2.8 7.8 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.21 EGR31280.1 - 0.18 11.3 0.0 0.49 9.8 0.0 1.6 2 0 0 2 2 2 0 Prolyl oligopeptidase family ASH PF15780.5 EGR31281.1 - 2.3e-07 30.9 0.5 0.0035 17.5 0.1 5.6 6 0 0 6 6 6 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 EGR31281.1 - 4.8e-07 29.6 7.1 3.8e-06 26.7 0.1 4.9 5 0 0 5 5 5 1 MSP (Major sperm protein) domain FixG_C PF11614.8 EGR31281.1 - 0.099 12.9 10.1 0.59 10.4 0.0 5.0 5 0 0 5 5 5 0 IG-like fold at C-terminal of FixG, putative oxidoreductase TMEM131_like PF12371.8 EGR31281.1 - 0.32 11.3 12.7 4.4 7.6 0.1 5.3 7 1 0 7 7 7 0 Transmembrane protein 131-like Pkinase PF00069.25 EGR31282.1 - 1.5e-63 214.6 0.0 1.9e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31282.1 - 2.3e-33 115.6 0.0 3e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31282.1 - 0.0019 17.6 0.0 0.0066 15.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EGR31282.1 - 0.0067 16.1 0.2 3.2 7.3 0.1 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGR31282.1 - 0.0089 14.8 0.0 0.013 14.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EGR31283.1 - 1.3e-59 201.7 0.4 2e-59 201.1 0.4 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31283.1 - 2e-44 151.8 0.1 3e-44 151.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR31283.1 - 3.7e-09 35.9 0.0 1.9e-08 33.5 0.0 2.0 1 1 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGR31283.1 - 0.071 13.0 0.0 3.8 7.3 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family ABC1 PF03109.16 EGR31283.1 - 0.071 13.3 0.8 0.27 11.4 0.0 2.2 2 1 1 3 3 3 0 ABC1 family FTA2 PF13095.6 EGR31283.1 - 0.33 10.6 7.7 0.56 9.8 0.3 2.7 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Endosulfine PF04667.17 EGR31284.1 - 0.0005 20.1 3.1 0.00056 20.0 3.1 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Adap_comp_sub PF00928.21 EGR31285.1 - 4.7e-32 111.4 0.9 6.7e-32 110.9 0.9 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGR31285.1 - 1.5e-05 24.9 4.4 3.6e-05 23.7 4.4 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Inhibitor_I36 PF03995.13 EGR31285.1 - 0.00062 19.6 0.3 0.0011 18.9 0.3 1.4 1 0 0 1 1 1 1 Peptidase inhibitor family I36 DUF2491 PF10679.9 EGR31285.1 - 0.021 14.0 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) Crystall PF00030.19 EGR31285.1 - 0.048 13.9 0.6 0.11 12.8 0.6 1.6 1 0 0 1 1 1 0 Beta/Gamma crystallin Crystall_3 PF08964.10 EGR31285.1 - 0.46 10.7 6.6 0.97 9.6 0.1 3.3 4 0 0 4 4 4 0 Beta/Gamma crystallin GBP PF02263.19 EGR31286.1 - 2.6e-61 207.2 0.1 2.6e-61 207.2 0.1 4.0 2 1 2 4 4 4 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 EGR31286.1 - 2.7e-09 36.9 46.2 2.7e-09 36.9 46.2 3.9 2 1 2 4 4 4 1 Guanylate-binding protein, C-terminal domain MMR_HSR1 PF01926.23 EGR31286.1 - 0.009 16.1 0.0 0.086 12.9 0.0 2.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase TPR_2 PF07719.17 EGR31287.1 - 1.1e-12 47.1 0.0 0.00099 19.0 0.0 4.6 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGR31287.1 - 2.6e-12 45.9 2.1 0.00028 20.9 0.0 5.5 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGR31287.1 - 1.6e-10 40.3 1.1 0.0008 19.1 0.0 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGR31287.1 - 7e-06 26.5 0.0 0.02 15.4 0.0 2.8 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGR31287.1 - 1.6e-05 24.5 0.0 0.12 12.1 0.0 4.0 2 1 2 4 4 4 2 TPR repeat TPR_17 PF13431.6 EGR31287.1 - 0.00092 19.4 2.1 0.4 11.2 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGR31287.1 - 0.023 14.8 0.0 0.75 10.0 0.0 2.9 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EGR31287.1 - 0.026 13.9 0.1 0.062 12.7 0.0 1.5 2 0 0 2 2 2 0 MalT-like TPR region Ribosomal_S7 PF00177.21 EGR31287.1 - 0.029 14.0 0.0 0.11 12.2 0.0 2.0 2 1 0 2 2 2 0 Ribosomal protein S7p/S5e AbiGi PF10899.8 EGR31287.1 - 0.075 12.9 1.6 0.1 12.4 0.2 1.9 2 0 0 2 2 2 0 Putative abortive phage resistance protein AbiGi, antitoxin TPR_14 PF13428.6 EGR31287.1 - 0.17 12.8 0.0 60 4.8 0.0 3.6 2 2 2 4 4 4 0 Tetratricopeptide repeat Uteroglobin PF01099.17 EGR31288.1 - 0.51 10.7 6.2 0.34 11.3 0.2 3.4 3 0 0 3 3 3 0 Uteroglobin family VSP PF03302.13 EGR31290.1 - 2.8e-07 29.7 96.3 0.0072 15.2 21.4 4.0 1 1 3 4 4 4 4 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EGR31290.1 - 0.0038 17.4 86.9 0.085 13.0 14.4 4.5 1 1 4 5 5 5 5 Furin-like repeat, cysteine-rich DUF4215 PF13948.6 EGR31290.1 - 0.051 14.0 4.9 0.051 14.0 4.9 9.1 3 2 2 5 5 5 0 Domain of unknown function (DUF4215) Kelch_1 PF01344.25 EGR31291.1 - 1.4e-34 117.4 8.3 8.4e-11 41.3 0.0 4.5 4 1 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 EGR31291.1 - 1.6e-26 91.7 4.5 5.5e-07 29.7 0.0 4.3 3 1 1 4 4 4 4 Kelch motif Kelch_4 PF13418.6 EGR31291.1 - 4.7e-25 87.4 2.2 2.2e-06 27.6 0.0 4.3 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 EGR31291.1 - 1.4e-17 63.5 1.0 3.4e-05 24.0 0.0 4.2 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.15 EGR31291.1 - 5.8e-14 51.4 0.7 0.00011 22.0 0.0 4.4 4 0 0 4 4 4 3 Kelch motif MORN PF02493.20 EGR31291.1 - 1.9e-12 46.3 15.5 5.9e-08 32.1 1.2 5.1 5 0 0 5 5 5 2 MORN repeat Kelch_5 PF13854.6 EGR31291.1 - 7.6e-12 45.0 8.8 0.0061 16.5 0.0 4.6 5 0 0 5 5 5 4 Kelch motif SRP72 PF08492.12 EGR31292.1 - 0.063 13.7 3.9 0.11 12.9 3.9 1.5 1 0 0 1 1 1 0 SRP72 RNA-binding domain Rad60-SLD PF11976.8 EGR31292.1 - 0.077 12.8 0.4 0.19 11.6 0.4 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGR31292.1 - 0.083 12.6 0.4 0.59 9.9 0.4 2.0 1 1 0 1 1 1 0 Ubiquitin family Copine PF07002.16 EGR31293.1 - 3e-53 180.5 0.0 4.7e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 EGR31293.1 - 1.2e-13 51.2 0.6 9.3e-08 32.3 0.1 2.5 2 0 0 2 2 2 2 C2 domain ATP-grasp_3 PF02655.14 EGR31293.1 - 0.071 13.2 0.6 0.18 11.9 0.2 1.9 2 0 0 2 2 2 0 ATP-grasp domain vWA-TerF-like PF10138.9 EGR31293.1 - 0.083 13.0 0.0 0.16 12.1 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus Acyl-CoA_dh_1 PF00441.24 EGR31294.1 - 3.7e-31 108.4 0.2 5.8e-31 107.7 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGR31294.1 - 1.3e-21 77.4 0.0 2e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGR31294.1 - 2.3e-21 75.8 0.0 3.9e-21 75.0 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGR31294.1 - 3.4e-09 37.1 0.0 5.1e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain WD40 PF00400.32 EGR31295.1 - 1.1e-69 228.6 9.1 2.3e-07 31.4 0.0 8.1 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR31295.1 - 1.3e-22 79.9 0.4 0.0035 17.6 0.0 7.2 1 1 5 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGR31295.1 - 2.1e-12 47.0 2.1 0.0034 16.8 0.1 4.3 2 1 1 4 4 4 4 WD40-like domain eIF2A PF08662.11 EGR31295.1 - 1.7e-09 37.8 3.0 0.00051 20.0 0.2 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGR31295.1 - 9.3e-07 28.1 4.7 0.049 12.6 0.1 5.1 1 1 4 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGR31295.1 - 3.6e-06 25.9 1.6 1.1 7.8 0.0 5.7 3 2 3 6 6 6 3 Nucleoporin Nup120/160 WD40_3 PF15911.5 EGR31295.1 - 0.004 17.1 0.1 0.91 9.6 0.0 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat Frtz PF11768.8 EGR31295.1 - 0.011 14.1 0.0 3 6.0 0.0 3.4 3 1 1 4 4 4 0 WD repeat-containing and planar cell polarity effector protein Fritz Marek_SORF3 PF07153.11 EGR31295.1 - 0.1 11.9 0.1 0.38 10.1 0.1 1.9 1 1 1 2 2 2 0 Marek's disease-like virus SORF3 protein Zip PF02535.22 EGR31297.1 - 4.9e-50 170.6 2.4 1e-49 169.6 2.4 1.4 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4678 PF15727.5 EGR31297.1 - 0.0061 15.9 3.0 0.009 15.3 3.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4678) ETRAMP PF09716.10 EGR31297.1 - 0.024 14.7 0.9 0.024 14.7 0.9 4.6 4 2 1 5 5 5 0 Malarial early transcribed membrane protein (ETRAMP) Neur_chan_memb PF02932.16 EGR31297.1 - 0.72 9.9 8.2 0.37 10.8 5.0 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region COPIIcoated_ERV PF07970.12 EGR31298.1 - 1.7e-18 67.3 1.7 2e-18 67.1 1.7 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGR31298.1 - 0.00043 20.6 2.5 0.00044 20.5 0.1 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) SLH PF00395.20 EGR31298.1 - 0.03 14.3 0.2 0.089 12.8 0.2 1.9 1 1 0 1 1 1 0 S-layer homology domain DUF676 PF05057.14 EGR31299.1 - 4.5e-35 121.1 0.0 7.9e-35 120.3 0.0 1.3 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGR31299.1 - 2.3e-06 27.6 0.1 5e-06 26.5 0.1 1.6 1 1 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 EGR31299.1 - 8.7e-05 22.4 0.1 0.00018 21.4 0.0 1.5 2 0 0 2 2 2 1 Lipase (class 3) RE_HaeIII PF09556.10 EGR31299.1 - 0.0029 16.8 0.8 0.0057 15.8 0.5 1.6 1 1 1 2 2 2 1 HaeIII restriction endonuclease PGAP1 PF07819.13 EGR31299.1 - 0.0033 17.2 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 EGR31299.1 - 0.012 14.8 1.1 0.014 14.6 0.2 1.5 2 0 0 2 2 2 0 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 EGR31299.1 - 0.017 14.6 0.1 0.28 10.6 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 EGR31299.1 - 0.2 10.9 0.0 0.32 10.2 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Bromodomain PF00439.25 EGR31300.1 - 1.9e-20 72.7 2.0 1.9e-20 72.7 2.0 2.6 2 1 0 2 2 2 1 Bromodomain MAP17 PF15807.5 EGR31300.1 - 0.36 11.1 4.0 1 9.6 4.0 1.8 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 RIX1 PF08167.12 EGR31301.1 - 0.015 15.1 1.8 0.04 13.7 0.1 2.0 2 0 0 2 2 2 0 rRNA processing/ribosome biogenesis bZIP_1 PF00170.21 EGR31301.1 - 0.09 12.9 0.0 0.09 12.9 0.0 3.3 4 0 0 4 4 4 0 bZIP transcription factor LepB_GAP_C PF18227.1 EGR31301.1 - 0.26 11.9 7.1 2.5 8.7 0.4 2.6 2 1 0 2 2 2 0 LepB GAP domain C-terminal subdomain Hexapep PF00132.24 EGR31303.1 - 1.9e-13 49.5 10.7 0.00091 18.9 0.1 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGR31303.1 - 2.8e-05 23.8 13.3 0.084 12.6 0.3 4.1 3 1 0 3 3 3 3 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EGR31303.1 - 0.16 10.1 1.1 0.22 9.6 1.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 EGR31303.1 - 0.19 10.6 1.1 0.56 9.1 1.0 1.7 1 1 1 2 2 2 0 L-fucokinase PHM7_cyt PF14703.6 EGR31304.1 - 1.9e-13 51.0 11.5 6.2e-13 49.3 8.5 2.7 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter Atg14 PF10186.9 EGR31304.1 - 0.0025 17.0 6.1 0.0056 15.8 6.1 1.6 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 CBFD_NFYB_HMF PF00808.23 EGR31305.1 - 9.2e-06 25.9 0.0 1.6e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGR31305.1 - 0.0075 16.6 0.1 0.021 15.2 0.0 1.8 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Orbi_VP1 PF05788.12 EGR31305.1 - 0.037 11.6 0.2 0.048 11.3 0.2 1.0 1 0 0 1 1 1 0 Orbivirus RNA-dependent RNA polymerase (VP1) AMP-binding PF00501.28 EGR31307.1 - 7.8e-70 235.6 0.0 9.4e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGR31307.1 - 0.013 16.4 0.0 0.032 15.2 0.0 1.7 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain WD40 PF00400.32 EGR31308.1 - 1.3e-15 57.5 3.8 0.0083 17.0 0.1 8.4 9 0 0 9 9 9 4 WD domain, G-beta repeat TPR_2 PF07719.17 EGR31309.1 - 1.2e-08 34.3 0.2 0.001 19.0 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGR31309.1 - 8.1e-08 31.8 2.3 0.0048 16.7 0.2 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGR31309.1 - 3.5e-05 23.7 3.3 0.0022 18.1 0.2 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGR31309.1 - 0.00024 21.3 0.2 0.025 14.9 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 EGR31309.1 - 0.00073 19.6 0.6 0.00073 19.6 0.6 2.1 1 1 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 EGR31309.1 - 0.02 14.8 0.1 0.12 12.2 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGR31309.1 - 0.045 13.4 1.9 1.9 8.3 0.1 2.4 2 0 0 2 2 2 0 TPR repeat MHB PF16525.5 EGR31309.1 - 0.05 13.9 0.5 0.081 13.2 0.5 1.3 1 0 0 1 1 1 0 Haemophore, haem-binding DUF1043 PF06295.12 EGR31309.1 - 0.15 12.0 6.3 0.22 11.5 6.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2524 PF10732.9 EGR31309.1 - 0.21 11.9 7.7 0.43 10.9 1.6 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2524) DUF2207 PF09972.9 EGR31309.1 - 0.62 8.8 6.9 0.74 8.5 6.9 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DHHC PF01529.20 EGR31310.1 - 1.2e-36 125.8 22.1 1.2e-36 125.8 22.1 2.5 2 0 0 2 2 2 1 DHHC palmitoyltransferase PIG-P PF08510.12 EGR31310.1 - 1.6 8.6 11.0 0.055 13.4 4.5 1.9 2 0 0 2 2 2 0 PIG-P MARVEL PF01284.23 EGR31310.1 - 3.7 7.6 14.8 3.8 7.6 5.0 2.3 2 0 0 2 2 2 0 Membrane-associating domain Ras PF00071.22 EGR31311.1 - 3.7e-56 189.2 0.8 5.3e-56 188.7 0.8 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR31311.1 - 2.2e-28 98.9 0.6 6.5e-28 97.4 0.1 1.9 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR31311.1 - 2.2e-12 46.7 0.1 2.9e-12 46.4 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGR31311.1 - 2.9e-06 27.0 0.2 3.4e-06 26.7 0.2 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGR31311.1 - 5.9e-05 22.5 0.3 9.8e-05 21.8 0.3 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Parvo_NS1 PF01057.17 EGR31311.1 - 0.00012 21.2 0.6 0.00017 20.8 0.6 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 MMR_HSR1 PF01926.23 EGR31311.1 - 0.0018 18.3 0.1 0.0045 17.1 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF4550 PF15084.6 EGR31311.1 - 0.1 13.0 0.5 2.7 8.4 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4550) GAS PF13851.6 EGR31312.1 - 6.5e-30 104.0 39.6 6.5e-30 104.0 39.6 3.0 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 EGR31312.1 - 0.14 12.2 12.6 0.69 9.9 5.1 3.1 1 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ion_trans_2 PF07885.16 EGR31313.1 - 3.1e-07 30.2 5.3 3.1e-07 30.2 5.3 2.7 2 1 0 2 2 2 1 Ion channel Ion_trans PF00520.31 EGR31313.1 - 0.0028 16.9 19.6 0.01 15.1 19.6 1.9 1 1 0 1 1 1 1 Ion transport protein SK_channel PF03530.14 EGR31313.1 - 0.0066 16.4 0.4 0.0066 16.4 0.4 2.0 2 0 0 2 2 2 1 Calcium-activated SK potassium channel DUF202 PF02656.15 EGR31313.1 - 0.099 13.1 0.0 0.099 13.1 0.0 1.9 3 0 0 3 3 3 0 Domain of unknown function (DUF202) Ku PF02735.16 EGR31314.1 - 1e-48 165.8 0.9 1.8e-48 164.9 0.9 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EGR31314.1 - 1.5e-32 113.1 9.5 1.7e-32 113.0 7.6 1.9 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EGR31314.1 - 6.6e-09 36.4 0.6 6.6e-09 36.4 0.6 3.1 3 1 1 4 4 4 1 Ku70/Ku80 C-terminal arm Peptidase_S49 PF01343.18 EGR31315.1 - 5.5e-10 39.4 0.0 1.2e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Peptidase family S49 Oxidored_molyb PF00174.19 EGR31315.1 - 0.013 15.1 0.0 0.031 13.9 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase molybdopterin binding domain ACT_3 PF10000.9 EGR31315.1 - 0.074 13.0 0.1 0.17 11.9 0.1 1.5 1 0 0 1 1 1 0 ACT domain Aminotran_5 PF00266.19 EGR31316.1 - 3.3e-11 42.8 0.0 5.8e-11 41.9 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V Ribosomal_L26 PF16906.5 EGR31317.1 - 1e-13 51.5 0.6 1e-13 51.5 0.6 2.0 2 0 0 2 2 2 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EGR31317.1 - 3.2e-08 33.2 3.8 6.3e-08 32.3 3.8 1.5 1 0 0 1 1 1 1 KOW motif EpoR_lig-bind PF09067.10 EGR31317.1 - 0.046 13.9 0.3 0.082 13.1 0.3 1.3 1 0 0 1 1 1 0 Erythropoietin receptor, ligand binding TPR_2 PF07719.17 EGR31319.1 - 3.1e-14 51.9 4.9 2.5e-06 27.2 1.6 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGR31319.1 - 3.2e-13 48.8 9.6 2.8e-06 27.1 1.4 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TTC5_OB PF16669.5 EGR31319.1 - 1.2e-11 44.3 0.9 2e-11 43.6 0.9 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat protein 5 OB fold domain TPR_1 PF00515.28 EGR31319.1 - 4.6e-11 42.0 10.1 6.2e-07 29.0 3.2 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGR31319.1 - 3.3e-08 33.1 9.1 0.0056 16.3 3.6 4.4 3 1 1 4 4 4 3 TPR repeat TPR_12 PF13424.6 EGR31319.1 - 1e-06 28.9 0.6 0.014 15.7 0.1 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGR31319.1 - 4.6e-06 26.3 1.6 0.041 13.9 0.5 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGR31319.1 - 9.6e-06 25.6 2.0 0.16 12.4 0.4 4.1 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGR31319.1 - 0.0035 17.9 1.5 2.7 8.8 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGR31319.1 - 0.013 16.1 0.0 5 7.9 0.0 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGR31319.1 - 0.082 13.8 0.0 91 4.3 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat E2F_TDP PF02319.20 EGR31320.1 - 9.3e-08 32.0 2.7 9.3e-08 32.0 2.7 1.7 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain Longin PF13774.6 EGR31321.1 - 1.9e-19 69.5 2.4 3.1e-19 68.8 1.2 1.9 2 0 0 2 2 2 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EGR31321.1 - 8.9e-05 22.2 2.1 0.00018 21.2 2.1 1.6 1 0 0 1 1 1 1 Synaptobrevin Glyco_hydr_30_2 PF14587.6 EGR31321.1 - 0.019 14.6 1.5 0.022 14.3 1.5 1.1 1 0 0 1 1 1 0 O-Glycosyl hydrolase family 30 YgaB PF14182.6 EGR31321.1 - 0.11 12.9 3.3 11 6.5 0.3 3.1 2 1 1 3 3 3 0 YgaB-like protein Pkinase PF00069.25 EGR31322.1 - 3.7e-59 200.2 0.3 3.7e-59 200.2 0.3 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31322.1 - 1e-27 97.1 0.8 1.4e-27 96.6 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase zf-MYND PF01753.18 EGR31322.1 - 7.4e-11 42.0 14.0 1.8e-10 40.7 14.0 1.7 1 0 0 1 1 1 1 MYND finger FTA2 PF13095.6 EGR31322.1 - 9.1e-05 22.2 5.1 0.098 12.3 0.0 3.4 2 2 1 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGR31322.1 - 0.00035 19.5 1.6 0.00069 18.5 0.0 2.1 3 0 0 3 3 3 1 Fungal protein kinase Kdo PF06293.14 EGR31322.1 - 0.0019 17.6 0.6 0.0043 16.4 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR31322.1 - 0.013 15.4 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Metallophos PF00149.28 EGR31323.1 - 1.1e-22 81.5 0.3 5.8e-21 75.9 0.3 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Peptidase_S24 PF00717.23 EGR31324.1 - 1.1e-08 34.9 0.3 2.3e-08 33.9 0.1 1.6 2 0 0 2 2 2 1 Peptidase S24-like Ion_trans PF00520.31 EGR31325.1 - 1.7e-54 184.7 22.5 2.2e-54 184.3 22.5 1.1 1 0 0 1 1 1 1 Ion transport protein Lustrin_cystein PF14625.6 EGR31325.1 - 0.0088 16.4 1.6 0.015 15.6 1.6 1.4 1 0 0 1 1 1 1 Lustrin, cysteine-rich repeated domain PKD_channel PF08016.12 EGR31325.1 - 0.32 9.6 0.0 0.32 9.6 0.0 3.2 3 0 0 3 3 3 0 Polycystin cation channel Ion_trans PF00520.31 EGR31326.1 - 2.6e-85 285.6 61.1 1.2e-43 149.1 29.5 2.3 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 EGR31326.1 - 1.2e-05 24.2 40.1 0.039 12.7 15.1 4.5 2 2 2 4 4 4 4 Polycystin cation channel FAM176 PF14851.6 EGR31326.1 - 0.96 9.1 17.6 0.092 12.4 0.4 4.0 4 0 0 4 4 4 0 FAM176 family Ion_trans PF00520.31 EGR31327.1 - 9e-36 123.3 12.2 9e-36 123.3 12.2 1.8 2 0 0 2 2 2 1 Ion transport protein PKD_channel PF08016.12 EGR31327.1 - 0.00018 20.3 13.0 0.0097 14.6 3.6 2.3 1 1 1 2 2 2 2 Polycystin cation channel MA3 PF02847.17 EGR31328.1 - 2e-22 79.3 1.5 9.4e-22 77.1 1.5 2.3 1 0 0 1 1 1 1 MA3 domain PhoLip_ATPase_C PF16212.5 EGR31328.1 - 1.6e-14 54.3 2.6 1.7e-14 54.2 0.7 2.0 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EGR31328.1 - 1.5e-05 25.4 0.0 0.012 15.9 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGR31328.1 - 0.02 14.6 0.4 0.02 14.6 0.4 4.3 4 1 0 4 4 4 0 haloacid dehalogenase-like hydrolase DUF4392 PF14336.6 EGR31328.1 - 0.09 12.2 0.3 0.25 10.8 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) Presenilin PF01080.17 EGR31328.1 - 0.98 8.1 9.1 1.7 7.4 9.1 1.3 1 0 0 1 1 1 0 Presenilin SR-25 PF10500.9 EGR31328.1 - 4.3 6.9 29.5 6.4 6.3 29.5 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SecY PF00344.20 EGR31329.1 - 9.7e-63 212.2 14.3 1.5e-62 211.6 14.3 1.3 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EGR31329.1 - 5.1e-18 64.6 0.2 5.1e-18 64.6 0.2 2.1 2 0 0 2 2 2 1 Plug domain of Sec61p DUF1430 PF07242.11 EGR31329.1 - 0.036 14.3 7.4 5.6 7.3 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1430) Response_reg PF00072.24 EGR31330.1 - 1.3e-10 41.4 0.0 6.7e-07 29.5 0.0 2.3 1 1 1 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 EGR31330.1 - 0.0039 17.7 0.0 0.0068 16.9 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MOLO1 PF17175.4 EGR31330.1 - 0.059 13.5 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Modulator of levamisole receptor-1 HECT PF00632.25 EGR31331.1 - 9.3e-63 212.5 8.8 1.2e-62 212.2 8.8 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF1398 PF07166.11 EGR31331.1 - 0.28 11.3 4.0 0.77 9.8 2.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1398) Calici_coat_C PF08435.11 EGR31332.1 - 4.2 6.8 8.4 11 5.4 8.4 1.7 1 0 0 1 1 1 0 Calicivirus coat protein C-terminal Fez1 PF06818.15 EGR31333.1 - 0.0025 18.3 9.5 0.0031 18.0 9.5 1.1 1 0 0 1 1 1 1 Fez1 Tropomyosin_1 PF12718.7 EGR31333.1 - 0.14 12.3 13.0 0.18 12.0 13.0 1.3 1 0 0 1 1 1 0 Tropomyosin like T2SSE PF00437.20 EGR31333.1 - 0.18 10.9 0.9 0.24 10.4 0.9 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF4407 PF14362.6 EGR31333.1 - 0.62 9.4 7.4 0.7 9.2 7.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FapA PF03961.13 EGR31333.1 - 1.7 7.2 18.2 1.9 7.0 18.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Asp PF00026.23 EGR31334.1 - 2.3e-57 194.8 8.1 3.5e-57 194.2 8.1 1.3 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGR31334.1 - 6.7e-10 39.5 0.3 7.3e-09 36.1 0.3 2.2 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGR31334.1 - 0.044 14.4 0.0 21 5.8 0.0 3.0 2 1 0 2 2 2 0 Aspartyl protease UN_NPL4 PF11543.8 EGR31334.1 - 0.088 13.3 0.1 0.23 12.0 0.1 1.7 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 YTH PF04146.15 EGR31335.1 - 2.2e-19 70.0 3.9 9.3e-19 68.0 3.9 1.9 1 1 0 1 1 1 1 YT521-B-like domain NAD_binding_1 PF00175.21 EGR31335.1 - 0.083 13.5 0.6 10 6.8 0.0 2.5 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain Pkinase PF00069.25 EGR31338.1 - 3.1e-12 46.4 3.6 3.1e-12 46.4 3.6 1.8 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31338.1 - 3.7e-09 36.3 1.8 4.9e-09 35.9 1.5 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase PP2C PF00481.21 EGR31339.1 - 2.9e-38 132.0 0.4 3.1e-21 76.2 0.0 3.0 2 1 1 3 3 3 3 Protein phosphatase 2C SpoIIE PF07228.12 EGR31339.1 - 0.0013 18.6 0.0 0.57 10.1 0.0 2.2 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Tup_N PF08581.10 EGR31340.1 - 0.016 15.5 5.0 0.016 15.5 5.0 6.8 4 1 3 7 7 7 0 Tup N-terminal PGP_phosphatase PF09419.10 EGR31341.1 - 0.091 12.4 2.2 0.12 11.9 2.2 1.3 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase O-antigen_lig PF13425.6 EGR31341.1 - 2.3 6.9 10.0 2.6 6.7 10.0 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein NAPRTase_N PF17767.1 EGR31342.1 - 6e-32 110.7 2.1 6.6e-32 110.5 0.4 2.0 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_C PF17956.1 EGR31342.1 - 5.9e-13 49.2 0.0 1.2e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase PF04095.16 EGR31342.1 - 1.2e-10 41.5 0.1 2.4e-09 37.2 0.1 2.1 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family QRPTase_N PF02749.16 EGR31342.1 - 0.17 11.9 0.0 1.2 9.3 0.0 2.1 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain HSP70 PF00012.20 EGR31343.1 - 1.2e-256 852.7 16.0 2e-256 852.0 16.0 1.4 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGR31343.1 - 2.1e-14 53.1 3.2 2.1e-12 46.5 2.3 2.8 2 1 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EGR31343.1 - 0.00031 20.5 0.0 0.00085 19.1 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF2730 PF10805.8 EGR31343.1 - 0.022 14.8 0.4 0.067 13.3 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) FtsA PF14450.6 EGR31343.1 - 0.023 15.1 5.5 3.1 8.3 0.2 3.9 3 1 0 3 3 3 0 Cell division protein FtsA SASP PF00269.20 EGR31343.1 - 1.7 8.7 6.1 3.3 7.8 0.0 3.7 4 0 0 4 4 4 0 Small, acid-soluble spore proteins, alpha/beta type Efg1 PF10153.9 EGR31343.1 - 4 7.8 16.0 0.28 11.5 6.2 2.9 2 0 0 2 2 2 0 rRNA-processing protein Efg1 NFACT-R_1 PF05670.13 EGR31345.1 - 1.2e-24 87.1 2.0 1.7e-24 86.6 2.0 1.4 1 1 0 1 1 1 1 NFACT protein RNA binding domain DUF1036 PF06282.11 EGR31345.1 - 0.0094 16.5 2.8 0.013 16.0 2.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1036) DUF3189 PF11385.8 EGR31345.1 - 0.043 13.7 0.1 0.45 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3189) FKBP_C PF00254.28 EGR31346.1 - 0.044 14.1 0.2 0.11 12.8 0.2 1.8 1 1 0 1 1 1 0 FKBP-type peptidyl-prolyl cis-trans isomerase NAPRTase_C PF17956.1 EGR31346.1 - 0.073 13.5 3.4 0.33 11.4 0.5 2.4 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase C-terminal domain DUF5383 PF17355.2 EGR31347.1 - 0.0011 19.3 9.4 0.0013 19.1 9.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5383) Ferritin-like PF12902.7 EGR31347.1 - 0.013 15.4 3.7 0.015 15.2 3.7 1.1 1 0 0 1 1 1 0 Ferritin-like PDEase_I PF00233.19 EGR31348.1 - 1.3e-81 273.8 8.7 1.3e-81 273.8 8.7 1.9 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Ion_trans PF00520.31 EGR31348.1 - 2.7e-12 46.5 11.7 2.7e-12 46.5 11.7 2.2 2 1 0 2 2 2 1 Ion transport protein Peroxin-13_N PF04088.13 EGR31348.1 - 0.1 12.9 8.4 0.14 12.4 3.5 2.7 2 0 0 2 2 2 0 Peroxin 13, N-terminal region VSP PF03302.13 EGR31349.1 - 0.007 15.3 8.5 0.0079 15.1 8.5 1.1 1 0 0 1 1 1 1 Giardia variant-specific surface protein PolC_DP2 PF03833.13 EGR31349.1 - 1.3 6.7 6.2 1.5 6.6 6.2 1.0 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 VSP PF03302.13 EGR31350.1 - 2.4e-14 53.0 212.4 7.7e-08 31.6 38.1 8.1 1 1 7 9 9 9 6 Giardia variant-specific surface protein DNA_pol_phi PF04931.13 EGR31351.1 - 0.04 12.0 43.9 0.042 12.0 43.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nop53 PF07767.11 EGR31351.1 - 0.22 10.9 26.1 0.31 10.4 26.1 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Mpp10 PF04006.12 EGR31351.1 - 0.4 9.1 34.2 0.46 8.9 34.2 1.0 1 0 0 1 1 1 0 Mpp10 protein Nop14 PF04147.12 EGR31351.1 - 0.58 8.3 39.4 0.65 8.1 39.4 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EGR31351.1 - 0.79 7.9 32.3 0.9 7.8 32.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.11 EGR31351.1 - 1.1 9.3 24.6 1.3 9.0 24.6 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) YL1 PF05764.13 EGR31351.1 - 1.1 9.3 44.0 1.2 9.1 44.0 1.0 1 0 0 1 1 1 0 YL1 nuclear protein RR_TM4-6 PF06459.12 EGR31351.1 - 2.5 7.9 17.0 3 7.6 17.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Tim54 PF11711.8 EGR31351.1 - 2.5 6.8 17.9 3.1 6.5 17.9 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_pol_Rpc4 PF05132.14 EGR31351.1 - 3 8.3 11.9 3.5 8.0 11.9 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 SDA1 PF05285.12 EGR31351.1 - 4.5 6.6 39.8 5.2 6.4 39.8 1.0 1 0 0 1 1 1 0 SDA1 Vfa1 PF08432.10 EGR31351.1 - 7.7 6.8 20.9 12 6.2 20.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CLN3 PF02487.17 EGR31351.1 - 8.5 5.3 7.1 9.9 5.1 7.1 1.0 1 0 0 1 1 1 0 CLN3 protein Merozoite_SPAM PF07133.11 EGR31351.1 - 9.7 6.1 49.5 10 6.0 49.5 1.0 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) HEAT PF02985.22 EGR31352.1 - 3.3e-06 26.9 3.8 0.18 12.2 0.0 4.8 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 EGR31352.1 - 6.6e-06 26.3 11.2 0.00038 20.5 0.0 3.3 1 1 3 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGR31352.1 - 0.00023 21.5 0.0 0.015 15.6 0.0 3.0 3 1 0 3 3 3 1 HEAT repeats UME PF08064.13 EGR31352.1 - 0.0022 17.9 0.5 0.0069 16.3 0.0 2.1 2 1 0 2 2 2 1 UME (NUC010) domain DUF2536 PF10750.9 EGR31352.1 - 0.013 15.4 2.4 0.023 14.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) HEAT_EZ PF13513.6 EGR31352.1 - 0.019 15.4 0.0 8.3 7.0 0.0 3.0 2 0 0 2 2 2 0 HEAT-like repeat Nop52 PF05997.12 EGR31352.1 - 0.11 12.2 3.0 0.99 9.2 0.1 2.6 2 1 0 2 2 2 0 Nucleolar protein,Nop52 MKT1_N PF12247.8 EGR31352.1 - 0.16 12.3 0.5 6.6 7.2 0.0 3.0 3 0 0 3 3 3 0 Temperature dependent protein affecting M2 dsRNA replication Vac14_Fab1_bd PF12755.7 EGR31352.1 - 0.33 11.6 3.6 9 7.0 0.1 3.7 2 1 2 5 5 5 0 Vacuolar 14 Fab1-binding region Peptidase_M17 PF00883.21 EGR31353.1 - 4.9e-102 341.4 0.0 7e-102 340.9 0.0 1.2 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Ribosomal_L7Ae PF01248.26 EGR31353.1 - 5.6e-21 74.1 0.5 1.4e-20 72.8 0.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ion_trans PF00520.31 EGR31354.1 - 1.2e-18 67.2 39.9 4e-13 49.2 32.3 3.3 2 1 0 2 2 2 2 Ion transport protein Pkinase PF00069.25 EGR31355.1 - 3.8e-38 131.3 4.0 4.7e-38 131.1 4.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31355.1 - 9.7e-37 126.6 1.8 1.1e-36 126.4 1.8 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR31355.1 - 1.6e-05 24.1 2.4 2.2e-05 23.6 2.4 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGR31355.1 - 4.7e-05 22.8 0.2 7.3e-05 22.2 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGR31355.1 - 0.00017 21.0 0.1 0.00029 20.3 0.1 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR31355.1 - 0.027 13.2 0.5 0.036 12.9 0.5 1.3 1 0 0 1 1 1 0 Fungal protein kinase DHHC PF01529.20 EGR31356.1 - 1.1e-22 80.6 27.2 1.1e-22 80.6 27.2 4.1 3 1 0 3 3 3 1 DHHC palmitoyltransferase CtaG_Cox11 PF04442.14 EGR31357.1 - 2.3e-17 63.4 0.0 4e-17 62.7 0.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 zf-HC5HC2H_2 PF13832.6 EGR31358.1 - 1.8e-14 53.8 11.2 1.8e-14 53.8 11.2 2.2 2 1 1 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EGR31358.1 - 4.5e-09 36.4 7.5 4.5e-09 36.4 7.5 3.1 1 1 1 3 3 3 1 PHD-like zinc-binding domain PHD PF00628.29 EGR31358.1 - 1.2e-08 34.7 5.4 1.2e-08 34.7 5.4 4.5 4 1 1 5 5 5 1 PHD-finger PHD_2 PF13831.6 EGR31358.1 - 1.6e-07 30.7 2.1 1.6e-07 30.7 2.1 4.6 6 0 0 6 6 6 1 PHD-finger Zn_ribbon_17 PF17120.5 EGR31358.1 - 0.021 14.5 0.8 0.021 14.5 0.8 3.9 3 1 0 4 4 4 0 Zinc-ribbon, C4HC2 type C1_1 PF00130.22 EGR31358.1 - 1.5 8.8 23.7 0.14 12.1 0.7 4.1 4 1 0 4 4 4 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DnaJ PF00226.31 EGR31359.1 - 1.7e-16 60.0 0.8 1.7e-16 60.0 0.8 2.1 2 0 0 2 2 2 1 DnaJ domain NPC1_N PF16414.5 EGR31360.1 - 1.3e-08 34.8 1.2 1.3e-08 34.8 1.2 2.6 2 0 0 2 2 2 2 Niemann-Pick C1 N terminus CSD PF00313.22 EGR31360.1 - 1.8e-07 30.9 0.3 4.2e-07 29.7 0.3 1.6 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 EGR31360.1 - 0.0041 16.8 1.5 0.011 15.4 0.2 2.2 2 0 0 2 2 2 1 Ribonuclease B OB domain CBS PF00571.28 EGR31361.1 - 5.1e-20 71.7 0.0 4.3e-09 36.7 0.0 3.4 3 0 0 3 3 3 3 CBS domain VSP PF03302.13 EGR31361.1 - 1e-11 44.4 186.7 3.1e-07 29.6 45.7 7.0 2 2 5 7 7 7 5 Giardia variant-specific surface protein Asp-B-Hydro_N PF05279.11 EGR31361.1 - 9.2 6.3 16.3 16 5.4 16.3 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region VSP PF03302.13 EGR31362.1 - 0.00028 19.9 92.9 0.015 14.2 19.3 4.0 1 1 3 4 4 4 3 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EGR31362.1 - 0.5 10.5 91.1 0.57 10.4 2.0 5.3 1 1 3 5 5 5 0 Furin-like repeat, cysteine-rich FAD_binding_1 PF00667.20 EGR31364.1 - 7.4e-29 100.9 0.2 1.6e-28 99.8 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EGR31364.1 - 1.9e-24 86.5 3.1 6.7e-24 84.7 0.1 2.8 3 1 0 3 3 3 1 Flavodoxin NAD_binding_1 PF00175.21 EGR31364.1 - 4e-15 56.4 0.3 1.9e-14 54.3 0.1 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_NdrI PF07972.11 EGR31364.1 - 0.003 17.7 0.9 0.018 15.2 0.1 2.5 2 1 0 2 2 2 1 NrdI Flavodoxin like NAD_binding_6 PF08030.12 EGR31364.1 - 0.063 13.4 0.1 0.42 10.7 0.1 2.2 1 1 0 1 1 1 0 Ferric reductase NAD binding domain PP2C PF00481.21 EGR31365.1 - 9.8e-71 238.4 0.1 1.6e-70 237.7 0.1 1.3 1 1 0 1 1 1 1 Protein phosphatase 2C Imm72 PF15584.6 EGR31365.1 - 0.05 13.8 0.0 0.15 12.2 0.0 1.8 2 0 0 2 2 2 0 Immunity protein 72 Hydrolase PF00702.26 EGR31366.1 - 8.6e-10 39.2 0.1 1.3e-07 32.1 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGR31366.1 - 7.9e-05 22.7 0.0 0.00022 21.2 0.0 1.7 1 1 0 1 1 1 1 Cation transport ATPase (P-type) Phenol_monoox PF04663.12 EGR31366.1 - 0.026 14.7 0.6 0.065 13.4 0.6 1.7 1 0 0 1 1 1 0 Phenol hydroxylase conserved region Ras PF00071.22 EGR31367.1 - 1.9e-61 206.4 0.8 2.3e-61 206.1 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR31367.1 - 1.2e-35 122.3 0.2 1.7e-35 121.9 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR31367.1 - 6.7e-17 61.5 0.2 8.2e-17 61.2 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR31367.1 - 8.1e-07 29.1 0.4 1.2e-06 28.6 0.4 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGR31367.1 - 0.00019 20.9 0.1 0.00026 20.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGR31367.1 - 0.00061 19.7 1.5 0.36 10.7 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EGR31367.1 - 0.002 17.6 0.3 0.0033 16.9 0.3 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EGR31367.1 - 0.0021 17.6 0.6 0.023 14.3 0.6 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGR31367.1 - 0.009 15.5 0.9 0.082 12.4 0.9 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B TniB PF05621.11 EGR31367.1 - 0.01 15.3 0.0 0.021 14.2 0.0 1.5 2 0 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 EGR31367.1 - 0.011 16.0 0.1 0.028 14.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGR31367.1 - 0.012 15.3 0.3 0.019 14.7 0.3 1.7 1 1 0 1 1 1 0 AAA domain PRK PF00485.18 EGR31367.1 - 0.012 15.3 0.4 0.04 13.7 0.4 1.9 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 EGR31367.1 - 0.017 15.6 0.0 0.034 14.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_14 PF13173.6 EGR31367.1 - 0.019 15.0 0.2 0.035 14.1 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGR31367.1 - 0.02 15.5 0.3 0.04 14.5 0.3 1.6 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGR31367.1 - 0.077 12.7 0.1 0.74 9.6 0.0 2.4 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DNA_pol_E_B PF04042.16 EGR31367.1 - 0.078 12.3 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B NTPase_1 PF03266.15 EGR31367.1 - 0.082 12.8 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 NTPase Peptidase_M8 PF01457.16 EGR31368.1 - 6.9e-46 157.0 2.6 2.8e-40 138.5 0.0 4.0 3 1 1 4 4 4 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR31368.1 - 9.9e-07 28.7 8.8 9.9e-07 28.7 8.8 9.4 12 0 0 12 12 12 1 Tenascin EGF domain Abi_HHR PF07815.14 EGR31368.1 - 0.052 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Abl-interactor HHR Peptidase_M8 PF01457.16 EGR31372.1 - 3.9e-28 98.4 13.1 5.3e-25 88.1 0.3 4.2 3 2 1 4 4 4 2 Leishmanolysin VSP PF03302.13 EGR31372.1 - 6.7e-11 41.7 174.1 0.011 14.6 35.5 5.6 1 1 5 6 6 6 5 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EGR31372.1 - 0.012 15.8 13.0 0.012 15.8 13.0 10.0 1 1 7 9 9 9 0 Furin-like repeat, cysteine-rich Peptidase_M16 PF00675.20 EGR31374.1 - 1.2e-35 122.6 0.0 2e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) PSDC PF12588.8 EGR31374.1 - 0.023 14.7 0.1 0.049 13.6 0.1 1.5 1 0 0 1 1 1 0 Phophatidylserine decarboxylase DUF3169 PF11368.8 EGR31374.1 - 0.045 13.3 0.8 0.078 12.5 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Glyco_hydro_66 PF13199.6 EGR31374.1 - 0.093 11.4 1.9 1.8 7.1 0.6 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 66 Cnd1 PF12717.7 EGR31375.1 - 0.02 14.9 0.0 0.02 14.9 0.0 4.0 4 1 2 6 6 6 0 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 EGR31375.1 - 0.12 12.3 2.5 0.4 10.6 0.1 2.8 2 0 0 2 2 2 0 Importin-beta N-terminal domain TPR_1 PF00515.28 EGR31376.1 - 9.7e-72 234.1 61.8 2e-06 27.4 0.5 16.0 16 0 0 16 16 16 15 Tetratricopeptide repeat TPR_2 PF07719.17 EGR31376.1 - 3e-66 214.3 46.7 4.5e-05 23.2 0.5 16.0 16 0 0 16 16 16 14 Tetratricopeptide repeat TPR_11 PF13414.6 EGR31376.1 - 3.9e-45 151.3 52.5 1.7e-07 30.8 0.0 14.4 5 3 10 15 15 15 11 TPR repeat TPR_8 PF13181.6 EGR31376.1 - 6.9e-44 144.4 50.3 6.1e-06 26.0 0.9 15.2 15 0 0 15 15 15 9 Tetratricopeptide repeat TPR_12 PF13424.6 EGR31376.1 - 4.5e-31 107.0 31.4 5.2e-08 33.1 0.5 10.9 4 3 7 12 12 12 8 Tetratricopeptide repeat TPR_16 PF13432.6 EGR31376.1 - 2.2e-29 101.8 3.4 0.00051 20.6 0.1 9.6 7 2 3 11 11 11 7 Tetratricopeptide repeat TPR_17 PF13431.6 EGR31376.1 - 3.4e-28 95.9 42.5 0.028 14.8 0.0 15.7 16 1 1 17 17 17 7 Tetratricopeptide repeat TPR_9 PF13371.6 EGR31376.1 - 6.2e-26 90.4 0.3 0.019 15.1 0.0 10.4 5 3 6 11 11 11 7 Tetratricopeptide repeat TPR_14 PF13428.6 EGR31376.1 - 9.8e-20 69.6 2.1 0.15 13.0 0.0 10.8 7 4 5 12 12 12 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGR31376.1 - 1.4e-18 67.1 22.2 0.00058 20.3 0.1 8.1 6 2 3 9 9 9 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR31376.1 - 8e-17 61.2 42.1 0.0026 17.9 2.0 8.9 3 3 6 9 9 9 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EGR31376.1 - 3.5e-16 58.0 17.3 0.023 14.7 0.2 10.3 12 0 0 12 12 11 4 Tetratricopeptide repeat TPR_6 PF13174.6 EGR31376.1 - 3.1e-12 46.3 31.6 0.034 14.8 0.4 12.3 14 0 0 14 14 12 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGR31376.1 - 3.2e-10 39.5 31.4 0.01 15.7 0.1 11.5 13 0 0 13 13 13 3 Tetratricopeptide repeat TPR_20 PF14561.6 EGR31376.1 - 1.9e-08 34.5 9.3 0.52 10.7 0.0 6.7 5 2 1 7 7 7 2 Tetratricopeptide repeat NARP1 PF12569.8 EGR31376.1 - 0.00053 19.0 32.1 3.4 6.5 12.1 5.8 2 1 1 3 3 3 3 NMDA receptor-regulated protein 1 BTAD PF03704.17 EGR31376.1 - 0.0021 18.5 0.4 2.1 8.8 0.7 3.5 2 1 1 3 3 3 1 Bacterial transcriptional activator domain SHNi-TPR PF10516.9 EGR31376.1 - 0.018 14.5 16.3 6.6 6.3 0.0 8.3 10 0 0 10 10 9 0 SHNi-TPR DUF1955 PF09205.10 EGR31376.1 - 0.028 14.1 0.5 0.51 10.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1955) Urocanase_N PF17391.2 EGR31376.1 - 1.2 8.8 4.5 11 5.7 0.0 4.3 5 1 1 6 6 6 0 Urocanase N-terminal domain SPO22 PF08631.10 EGR31376.1 - 1.3 8.5 9.3 2.1 7.8 1.8 3.9 3 2 1 4 4 4 0 Meiosis protein SPO22/ZIP4 like DEAD PF00270.29 EGR31377.1 - 3.6e-34 118.1 0.1 6.7e-34 117.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR31377.1 - 1.1e-24 86.9 9.2 1.3e-24 86.7 0.3 3.6 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGR31377.1 - 8.3e-13 48.7 1.0 8.3e-13 48.7 1.0 2.6 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EGR31377.1 - 0.00098 18.8 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 SWI2/SNF2 ATPase AAA_19 PF13245.6 EGR31377.1 - 0.014 15.7 0.0 0.026 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGR31377.1 - 0.014 15.1 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Helicase_C_2 PF13307.6 EGR31377.1 - 0.056 13.6 0.2 0.42 10.8 0.0 2.1 2 0 0 2 2 2 0 Helicase C-terminal domain Bac_DnaA PF00308.18 EGR31377.1 - 0.096 12.5 4.5 0.068 13.0 1.3 2.1 2 0 0 2 2 2 0 Bacterial dnaA protein AAA_22 PF13401.6 EGR31377.1 - 0.17 12.1 0.8 3.1 8.1 0.6 2.5 1 1 0 1 1 1 0 AAA domain Zot PF05707.12 EGR31377.1 - 0.23 11.1 1.3 0.45 10.1 0.3 2.0 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) Chorein_N PF12624.7 EGR31378.1 - 1.9e-11 44.1 14.3 1.3e-09 38.2 10.9 6.8 6 2 1 7 7 7 3 N-terminal region of Chorein or VPS13 Bac_globin PF01152.21 EGR31380.1 - 6.5e-56 187.7 3.2 3e-14 53.2 0.1 4.2 4 0 0 4 4 4 4 Bacterial-like globin AhpC-TSA PF00578.21 EGR31380.1 - 4.6e-09 36.2 0.0 1.4e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGR31380.1 - 0.00046 19.9 0.0 0.00091 19.0 0.0 1.5 1 0 0 1 1 1 1 Redoxin Protoglobin PF11563.8 EGR31380.1 - 0.32 10.9 1.6 10 6.0 0.1 3.4 4 0 0 4 4 4 0 Protoglobin Cys_rich_FGFR PF00839.17 EGR31380.1 - 1.6 8.9 4.1 1.7 8.9 0.9 2.7 2 0 0 2 2 2 0 Cysteine rich repeat Piwi PF02171.17 EGR31382.1 - 2.2e-54 184.8 7.8 2.2e-54 184.8 7.8 2.0 2 1 0 2 2 2 1 Piwi domain PAZ PF02170.22 EGR31382.1 - 6.7e-29 100.4 9.4 2e-28 98.9 9.4 1.8 1 0 0 1 1 1 1 PAZ domain DUF4712 PF15830.5 EGR31382.1 - 0.053 13.2 0.4 0.1 12.3 0.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4712) PRK PF00485.18 EGR31383.1 - 1.6e-14 54.2 0.0 1.8e-14 54.0 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Parvo_NS1 PF01057.17 EGR31383.1 - 0.0058 15.8 0.0 0.0086 15.2 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_18 PF13238.6 EGR31383.1 - 0.085 13.4 0.0 0.1 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA domain cNMP_binding PF00027.29 EGR31384.1 - 3.6e-15 55.8 0.0 6.7e-15 54.9 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGR31384.1 - 5.2e-11 42.4 1.8 1.5e-10 40.9 1.8 1.8 1 0 0 1 1 1 1 Ion channel zf-CCHC PF00098.23 EGR31384.1 - 0.00074 19.5 0.4 0.0014 18.6 0.4 1.5 1 0 0 1 1 1 1 Zinc knuckle cPLA2_C2 PF18695.1 EGR31384.1 - 0.0037 17.2 0.3 2.4 8.2 0.1 2.9 2 0 0 2 2 2 2 Cytosolic phospholipases A2 C2-domain DFF-C PF09033.10 EGR31384.1 - 0.0051 16.7 1.3 0.0051 16.7 1.3 1.8 2 0 0 2 2 2 1 DNA Fragmentation factor 45kDa, C terminal domain TTL PF03133.15 EGR31385.1 - 1.8e-44 152.1 17.2 1.1e-26 93.6 2.4 2.2 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR31385.1 - 1.1e-08 34.6 1.9 2.5e-08 33.5 1.9 1.7 1 1 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR31385.1 - 1.5e-05 24.4 2.2 0.0068 15.7 0.0 2.6 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 EGR31385.1 - 0.035 13.6 0.2 0.21 11.1 0.0 2.3 2 0 0 2 2 2 0 D-ala D-ala ligase C-terminus Arc_PepC_II PF06847.11 EGR31385.1 - 1.9 9.0 5.7 1.8 9.2 0.4 2.7 2 1 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II ParcG PF10274.9 EGR31386.1 - 7.2e-43 146.8 0.6 8e-43 146.7 0.6 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein DUF520 PF04461.13 EGR31387.1 - 0.04 14.0 13.6 0.13 12.3 9.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF520) DUF5475 PF17569.2 EGR31387.1 - 2.1 8.7 11.2 14 6.1 1.1 4.1 3 1 1 4 4 4 0 Family of unknown function (DUF5475) DUF2115 PF09888.9 EGR31387.1 - 6.8 7.2 9.6 1.7 9.1 3.8 2.3 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Glyco_hydro_38N PF01074.22 EGR31388.1 - 2.1e-82 276.8 17.5 5.6e-82 275.4 16.4 2.3 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EGR31388.1 - 1.7e-22 80.5 7.0 1.7e-22 80.5 7.0 2.2 2 1 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EGR31388.1 - 3.1e-19 68.9 0.9 1.2e-18 67.1 0.9 2.0 1 0 0 1 1 1 1 Alpha mannosidase middle domain Thg1 PF04446.12 EGR31390.1 - 9.8e-49 164.5 0.7 9.8e-49 164.5 0.7 1.7 2 0 0 2 2 2 1 tRNAHis guanylyltransferase Thg1C PF14413.6 EGR31390.1 - 7.1e-25 87.5 0.4 1.8e-24 86.3 0.4 1.7 1 0 0 1 1 1 1 Thg1 C terminal domain Pkinase PF00069.25 EGR31390.1 - 2.4e-11 43.5 0.0 4.4e-11 42.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31390.1 - 0.00092 18.6 0.0 0.0022 17.3 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase malic PF00390.19 EGR31390.1 - 0.071 12.9 0.2 2.4 7.9 0.0 2.3 2 0 0 2 2 2 0 Malic enzyme, N-terminal domain Edc3_linker PF16598.5 EGR31390.1 - 0.13 13.0 0.0 1.8 9.3 0.0 2.4 2 0 0 2 2 2 0 Linker region of enhancer of mRNA-decapping protein 3 Pkinase PF00069.25 EGR31391.1 - 5.9e-32 111.1 0.0 9.4e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31391.1 - 3e-08 33.3 0.0 4.3e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR31391.1 - 0.045 13.7 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family NAR2 PF16974.5 EGR31391.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 High-affinity nitrate transporter accessory UCH PF00443.29 EGR31392.1 - 4.2e-63 213.2 9.0 4.9e-63 213.0 9.0 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR31392.1 - 9.4e-12 45.1 10.9 1e-10 41.8 10.9 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase NOB1_Zn_bind PF08772.11 EGR31392.1 - 0.026 14.7 0.7 0.066 13.4 0.1 2.1 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like DUF4756 PF15948.5 EGR31392.1 - 0.067 13.0 0.1 0.18 11.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4756) TPR_1 PF00515.28 EGR31393.1 - 3e-105 340.2 59.8 1.1e-09 37.6 0.0 15.5 15 0 0 15 15 15 15 Tetratricopeptide repeat TPR_2 PF07719.17 EGR31393.1 - 9.2e-89 284.6 39.2 1.2e-07 31.2 0.2 15.4 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_11 PF13414.6 EGR31393.1 - 3.9e-69 228.1 45.5 2.9e-09 36.5 0.3 15.5 4 3 11 15 15 15 15 TPR repeat TPR_8 PF13181.6 EGR31393.1 - 3.1e-65 211.0 44.2 3.7e-06 26.7 0.0 14.9 15 0 0 15 15 15 12 Tetratricopeptide repeat TPR_17 PF13431.6 EGR31393.1 - 4.2e-56 183.4 37.8 8.4e-05 22.7 0.0 15.1 15 0 0 15 15 14 12 Tetratricopeptide repeat TPR_16 PF13432.6 EGR31393.1 - 6.3e-41 138.8 0.0 1.5e-05 25.6 0.0 9.1 6 1 2 9 9 9 8 Tetratricopeptide repeat TPR_12 PF13424.6 EGR31393.1 - 4.2e-40 135.9 14.0 4.1e-07 30.2 0.0 9.6 3 3 4 9 9 9 8 Tetratricopeptide repeat TPR_9 PF13371.6 EGR31393.1 - 1.1e-35 121.6 0.0 0.00068 19.7 0.0 10.7 3 3 7 11 11 11 8 Tetratricopeptide repeat TPR_7 PF13176.6 EGR31393.1 - 1.4e-29 99.9 15.2 0.02 14.9 0.0 13.6 13 1 1 14 14 14 8 Tetratricopeptide repeat TPR_6 PF13174.6 EGR31393.1 - 1.3e-24 85.1 23.5 0.0015 19.0 0.0 13.6 14 0 0 14 14 14 6 Tetratricopeptide repeat TPR_19 PF14559.6 EGR31393.1 - 2.1e-22 79.4 19.5 0.00019 21.8 0.0 9.9 6 1 5 11 11 11 6 Tetratricopeptide repeat TPR_14 PF13428.6 EGR31393.1 - 8.3e-19 66.7 0.1 4.2 8.4 0.0 12.1 6 4 7 13 13 12 2 Tetratricopeptide repeat zf-HC5HC2H_2 PF13832.6 EGR31393.1 - 5.9e-15 55.4 8.4 5.9e-15 55.4 8.4 3.0 3 0 0 3 3 2 1 PHD-zinc-finger like domain ANAPC3 PF12895.7 EGR31393.1 - 2.6e-14 53.2 28.0 0.00099 19.3 1.3 8.1 5 2 3 8 8 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EGR31393.1 - 6.9e-11 41.7 14.9 0.036 13.9 0.1 10.3 11 0 0 11 11 10 2 Tetratricopeptide repeat DUF3856 PF12968.7 EGR31393.1 - 5.6e-10 39.4 0.5 2.8 8.0 0.0 7.0 5 2 3 8 8 7 1 Domain of Unknown Function (DUF3856) NARP1 PF12569.8 EGR31393.1 - 2e-09 36.9 19.5 0.00023 20.2 0.0 5.8 3 2 2 6 6 6 3 NMDA receptor-regulated protein 1 TPR_15 PF13429.6 EGR31393.1 - 2.2e-09 37.0 1.8 3.5 6.7 0.0 7.2 3 2 3 7 7 7 1 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGR31393.1 - 4.8e-09 35.5 21.9 0.27 10.7 0.0 10.2 10 0 0 10 10 10 3 SHNi-TPR zf-HC5HC2H PF13771.6 EGR31393.1 - 1.3e-06 28.5 7.9 1.3e-06 28.5 7.9 4.0 1 1 2 3 3 2 1 PHD-like zinc-binding domain TPR_5 PF12688.7 EGR31393.1 - 5.5e-06 26.6 2.1 0.038 14.2 0.0 5.1 7 0 0 7 7 4 1 Tetratrico peptide repeat PHD PF00628.29 EGR31393.1 - 3.9e-05 23.5 28.1 0.0011 18.8 7.3 4.1 2 1 0 3 3 3 2 PHD-finger PHD_2 PF13831.6 EGR31393.1 - 0.0014 18.1 6.5 0.0058 16.2 6.5 2.2 1 1 0 1 1 1 1 PHD-finger Fis1_TPR_C PF14853.6 EGR31393.1 - 0.0019 18.2 19.6 0.41 10.7 0.2 7.0 6 2 1 7 7 5 1 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 EGR31393.1 - 0.0019 18.2 33.4 5.3 7.2 0.1 11.0 11 2 2 13 13 11 1 MIT (microtubule interacting and transport) domain TPR_20 PF14561.6 EGR31393.1 - 0.0031 17.8 4.4 5.5 7.4 0.2 4.9 6 0 0 6 6 4 1 Tetratricopeptide repeat DUF4428 PF14471.6 EGR31393.1 - 0.089 12.7 7.1 0.27 11.2 1.6 4.0 4 0 0 4 4 3 0 Domain of unknown function (DUF4428) rve_2 PF13333.6 EGR31393.1 - 0.27 11.5 5.8 8.4 6.7 0.1 5.1 5 0 0 5 5 4 0 Integrase core domain PDEase_I PF00233.19 EGR31394.1 - 3.4e-63 213.5 6.8 3.9e-63 213.3 6.8 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase DUF763 PF05559.11 EGR31394.1 - 0.095 11.9 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF763) CHORD PF04968.12 EGR31395.1 - 3.8e-39 133.2 29.8 8.3e-23 80.9 11.8 3.3 3 0 0 3 3 3 2 CHORD Kelch_1 PF01344.25 EGR31395.1 - 2.3e-25 87.9 2.4 3.4e-07 29.7 0.0 4.5 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 EGR31395.1 - 4.9e-21 74.2 3.4 2e-06 27.9 0.5 4.5 2 2 2 4 4 4 4 Kelch motif Kelch_4 PF13418.6 EGR31395.1 - 2.9e-18 65.6 0.5 6e-05 23.0 0.0 4.5 4 0 0 4 4 4 4 Galactose oxidase, central domain Kelch_2 PF07646.15 EGR31395.1 - 2.1e-12 46.5 3.6 0.002 18.0 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 EGR31395.1 - 4.2e-07 29.8 1.7 0.4 10.7 0.1 3.5 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 EGR31395.1 - 1.2e-05 25.5 0.5 4.7 7.6 0.1 4.7 4 1 0 4 4 4 2 Galactose oxidase, central domain BTK PF00779.19 EGR31395.1 - 0.037 13.9 7.6 0.36 10.7 1.2 2.8 2 0 0 2 2 2 0 BTK motif PAS_9 PF13426.7 EGR31396.1 - 1.9e-05 24.9 0.1 0.00022 21.5 0.1 3.0 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EGR31396.1 - 0.0023 17.9 7.0 0.0047 16.9 0.0 3.3 4 0 0 4 4 4 1 PAS fold YobH PF13996.6 EGR31396.1 - 0.044 13.8 1.4 0.2 11.7 1.4 2.2 1 0 0 1 1 1 0 YobH-like protein Got1 PF04178.12 EGR31397.1 - 2.2e-34 118.3 15.0 3.3e-34 117.7 15.0 1.3 1 0 0 1 1 1 1 Got1/Sft2-like family Ebola_NP PF05505.12 EGR31397.1 - 1.1 7.5 1.8 1.3 7.2 1.8 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein DUF5373 PF17343.2 EGR31397.1 - 5.9 6.7 11.3 25 4.6 11.3 1.8 1 1 0 1 1 1 0 Family of unknown function (DUF5373) MqsR_toxin PF15723.5 EGR31398.1 - 3.3e-05 24.2 30.9 0.38 11.1 0.9 7.9 7 0 0 7 7 7 4 Motility quorum-sensing regulator, toxin of MqsA Ribosomal_L2 PF00181.23 EGR31398.1 - 0.022 14.7 2.4 1.1e+02 2.9 0.0 5.2 4 0 0 4 4 4 0 Ribosomal Proteins L2, RNA binding domain DUF2759 PF10958.8 EGR31398.1 - 0.34 10.7 1.5 30 4.4 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2759) Ribosomal_S21e PF01249.18 EGR31400.1 - 1.7e-29 101.7 0.0 2e-29 101.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e Ribosomal_60s PF00428.19 EGR31401.1 - 2.1e-14 53.8 8.5 2.8e-14 53.5 8.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Pkinase PF00069.25 EGR31402.1 - 2.5e-50 171.3 6.9 5.1e-50 170.3 6.9 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31402.1 - 1.4e-22 80.2 1.1 3.1e-22 79.1 1.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR31402.1 - 0.0015 17.4 1.4 0.0028 16.5 0.3 1.8 1 1 1 2 2 2 1 Fungal protein kinase PH PF00169.29 EGR31402.1 - 0.71 10.4 6.4 0.076 13.5 1.0 2.3 3 0 0 3 3 3 0 PH domain Mito_carr PF00153.27 EGR31403.1 - 8.8e-51 169.8 7.5 9e-21 73.6 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein p25-alpha PF05517.12 EGR31404.1 - 5.6e-11 42.8 16.9 3.4e-09 37.1 1.0 4.1 3 1 1 4 4 4 3 p25-alpha RFX_DNA_binding PF02257.15 EGR31404.1 - 0.15 12.7 2.2 8.9 7.0 0.1 3.4 2 1 1 3 3 3 0 RFX DNA-binding domain DUF1640 PF07798.11 EGR31404.1 - 2.1 8.3 10.5 3 7.9 3.9 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF1640) Mito_carr PF00153.27 EGR31405.1 - 0.00021 21.1 1.0 0.0039 17.1 0.0 2.5 1 1 1 2 2 2 1 Mitochondrial carrier protein PseudoU_synth_2 PF00849.22 EGR31406.1 - 0.094 12.8 0.1 0.16 12.1 0.1 1.3 1 0 0 1 1 1 0 RNA pseudouridylate synthase Spectrin PF00435.21 EGR31407.1 - 0.00057 20.3 6.2 0.00057 20.3 6.2 4.6 1 1 3 4 4 4 1 Spectrin repeat Spc7 PF08317.11 EGR31407.1 - 0.0045 15.9 20.1 0.0045 15.9 20.1 3.3 1 1 4 5 5 5 2 Spc7 kinetochore protein HeLo PF14479.6 EGR31407.1 - 0.11 12.3 13.2 0.6 9.9 13.2 2.5 1 1 0 1 1 1 0 Prion-inhibition and propagation YtxH PF12732.7 EGR31407.1 - 0.3 11.7 3.9 2.5 8.7 0.1 3.0 1 1 1 2 2 2 0 YtxH-like protein DUF3450 PF11932.8 EGR31407.1 - 1 8.6 31.2 0.022 14.1 12.4 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF948 PF06103.11 EGR31407.1 - 1.2 9.5 12.1 3.7 7.9 0.4 3.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) HAP1_N PF04849.13 EGR31407.1 - 4.2 6.5 35.5 2.7 7.1 30.7 2.6 1 1 2 3 3 3 0 HAP1 N-terminal conserved region Suppressor_APC PF11414.8 EGR31407.1 - 8 6.6 13.7 96 3.2 7.7 3.6 2 1 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein Cation_ATPase_C PF00689.21 EGR31408.1 - 9e-21 74.4 14.5 9e-21 74.4 14.5 3.8 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGR31408.1 - 1.1e-18 67.1 0.1 3.4e-18 65.5 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGR31408.1 - 2.3e-15 56.6 0.1 2.3e-15 56.6 0.1 3.0 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EGR31408.1 - 3e-07 30.9 0.0 9.8e-07 29.3 0.0 1.9 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGR31408.1 - 0.00069 19.3 0.0 0.0021 17.7 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus DHQ_synthase PF01761.20 EGR31409.1 - 5e-26 91.4 0.0 6.4e-26 91.1 0.0 1.0 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 EGR31409.1 - 0.008 15.9 0.6 0.66 9.6 0.0 2.1 1 1 1 2 2 2 2 Iron-containing alcohol dehydrogenase RTT107_BRCT_6 PF16771.5 EGR31409.1 - 0.081 13.1 1.8 0.088 13.0 0.6 1.6 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain Shikimate_dh_N PF08501.11 EGR31410.1 - 4.4e-09 36.5 0.1 9.6e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain DHquinase_I PF01487.15 EGR31410.1 - 5e-08 33.5 0.0 8.1e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Type I 3-dehydroquinase DUF2671 PF10877.8 EGR31410.1 - 0.035 13.9 0.1 0.11 12.3 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2671) Shikimate_DH PF01488.20 EGR31410.1 - 0.036 14.1 0.0 0.1 12.6 0.0 1.7 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF412 PF04217.13 EGR31411.1 - 0.058 13.3 3.3 0.054 13.4 1.8 1.7 1 1 1 2 2 2 0 Protein of unknown function, DUF412 DUF3854 PF12965.7 EGR31411.1 - 0.1 12.6 4.5 0.13 12.3 3.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3854) FmiP_Thoc5 PF09766.9 EGR31411.1 - 0.34 10.1 13.7 0.15 11.3 11.2 1.5 1 1 0 1 1 1 0 Fms-interacting protein/Thoc5 DUF3959 PF13105.6 EGR31411.1 - 0.87 9.0 8.6 1.2 8.6 8.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3959) Csm2_III-A PF03750.13 EGR31411.1 - 2.5 9.0 15.0 4.8 8.1 14.6 1.7 1 1 0 1 1 1 0 Csm2 Type III-A Epimerase PF01370.21 EGR31413.1 - 6.9e-08 32.2 0.1 1.2e-06 28.2 0.1 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGR31413.1 - 1.6e-06 27.4 0.1 6.7e-05 22.1 0.0 2.3 2 1 0 2 2 2 1 RmlD substrate binding domain 3Beta_HSD PF01073.19 EGR31413.1 - 0.0003 19.9 0.0 0.0054 15.8 0.0 2.1 1 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EGR31413.1 - 0.0014 18.5 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGR31413.1 - 0.0037 16.8 0.0 0.0079 15.8 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 EGR31413.1 - 0.17 11.0 3.9 2.1 7.4 0.2 3.0 2 1 1 3 3 3 0 Male sterility protein Tubulin PF00091.25 EGR31414.1 - 2.5e-69 233.5 0.0 3.6e-69 232.9 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGR31414.1 - 1.9e-51 173.5 0.7 3.3e-51 172.7 0.1 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EGR31414.1 - 0.0046 16.6 0.0 0.015 15.0 0.0 1.9 2 0 0 2 2 2 1 Tubulin domain tRNA_bind PF01588.20 EGR31415.1 - 5.7e-11 42.4 0.1 2.1e-10 40.6 0.1 1.8 2 0 0 2 2 2 1 Putative tRNA binding domain PUF PF00806.19 EGR31416.1 - 3.5e-36 120.9 10.7 1.2e-09 37.3 0.1 6.0 5 0 0 5 5 5 5 Pumilio-family RNA binding repeat Malate_synthase PF01274.22 EGR31417.1 - 1.7e-168 561.2 0.0 2.1e-168 560.9 0.0 1.0 1 0 0 1 1 1 1 Malate synthase HpcH_HpaI PF03328.14 EGR31417.1 - 0.021 14.0 0.0 0.8 8.8 0.0 2.3 2 0 0 2 2 2 0 HpcH/HpaI aldolase/citrate lyase family YdaS_antitoxin PF15943.5 EGR31417.1 - 0.13 12.1 0.6 4.5 7.2 0.2 2.8 3 0 0 3 3 3 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Kinesin PF00225.23 EGR31418.1 - 6.5e-89 298.1 11.7 4.1e-58 196.9 6.1 2.3 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EGR31418.1 - 4.6e-22 78.6 7.3 6.2e-22 78.2 2.7 2.8 1 1 1 2 2 2 1 Microtubule binding Pkinase PF00069.25 EGR31418.1 - 4.4e-21 75.4 0.1 1.3e-20 73.9 0.1 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31418.1 - 3.2e-12 46.3 0.0 7e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3490 PF11995.8 EGR31418.1 - 0.048 13.5 1.3 0.13 12.0 1.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) SUIM_assoc PF16619.5 EGR31418.1 - 2.8 8.1 8.0 0.49 10.5 3.3 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Dopey_N PF04118.14 EGR31419.1 - 2e-88 296.5 8.1 2e-88 296.5 8.1 5.4 5 2 1 6 6 6 1 Dopey, N-terminal Neuraminidase PF18413.1 EGR31419.1 - 0.056 13.1 1.4 0.19 11.4 1.4 1.8 1 0 0 1 1 1 0 Neuraminidase-like domain WD40 PF00400.32 EGR31420.1 - 0.018 15.9 7.1 3.3 8.7 0.1 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat Chordopox_A13L PF05961.11 EGR31421.1 - 0.098 12.9 0.1 0.098 12.9 0.1 5.3 2 2 1 3 3 3 0 Chordopoxvirus A13L protein GDPD PF03009.17 EGR31423.1 - 7.9e-15 55.3 1.0 1.2e-14 54.7 1.0 1.3 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family DUF4550 PF15084.6 EGR31423.1 - 0.024 15.1 1.2 0.43 11.0 0.2 2.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4550) Flavodoxin_3 PF12641.7 EGR31423.1 - 0.048 13.3 0.1 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Flavodoxin domain DUF2854 PF11016.8 EGR31423.1 - 0.14 12.0 1.8 6.5 6.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2854) FH2 PF02181.23 EGR31424.1 - 2.9e-50 171.4 12.1 2.9e-50 171.4 12.1 2.4 2 1 0 2 2 2 1 Formin Homology 2 Domain AAA PF00004.29 EGR31425.1 - 2.3e-43 147.8 0.0 6.3e-43 146.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EGR31425.1 - 8.7e-15 54.5 0.0 6.5e-14 51.7 0.0 2.5 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain AAA_lid_3 PF17862.1 EGR31425.1 - 1.1e-07 31.6 0.0 8.9e-07 28.6 0.0 2.5 2 0 0 2 2 2 1 AAA+ lid domain RuvB_N PF05496.12 EGR31425.1 - 1.3e-06 28.2 0.0 2.2e-06 27.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 EGR31425.1 - 1e-05 25.5 0.1 0.0003 20.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGR31425.1 - 1.3e-05 25.7 0.7 0.0022 18.4 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 EGR31425.1 - 2.6e-05 24.4 0.0 5.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGR31425.1 - 3.3e-05 23.9 0.1 0.0024 17.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGR31425.1 - 6.6e-05 23.2 0.3 0.029 14.6 0.3 2.9 1 1 0 1 1 1 1 AAA domain TIP49 PF06068.13 EGR31425.1 - 0.0003 20.1 0.0 0.00045 19.5 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_24 PF13479.6 EGR31425.1 - 0.00032 20.5 0.0 0.00078 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGR31425.1 - 0.00038 20.3 0.0 0.00079 19.2 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 EGR31425.1 - 0.00041 19.6 0.1 0.0013 18.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EGR31425.1 - 0.0018 18.7 0.0 0.0061 16.9 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 EGR31425.1 - 0.0079 16.7 0.1 0.049 14.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.18 EGR31425.1 - 0.0089 15.9 0.0 0.028 14.3 0.0 1.8 1 1 0 1 1 1 1 Bacterial dnaA protein AAA_33 PF13671.6 EGR31425.1 - 0.0093 16.1 0.0 0.023 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGR31425.1 - 0.0095 15.5 0.1 0.41 10.2 0.1 2.3 1 1 0 2 2 2 1 AAA domain ATPase PF06745.13 EGR31425.1 - 0.012 15.0 2.7 2 7.7 0.0 2.9 2 1 1 3 3 3 0 KaiC PhoH PF02562.16 EGR31425.1 - 0.019 14.5 0.0 0.039 13.4 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein TsaE PF02367.17 EGR31425.1 - 0.019 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 EGR31425.1 - 0.037 13.4 0.0 0.085 12.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EGR31425.1 - 0.046 13.2 0.0 0.13 11.8 0.0 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 EGR31425.1 - 0.053 12.9 0.0 7.1 6.0 0.0 2.5 1 1 1 2 2 2 0 Bacterial TniB protein Parvo_NS1 PF01057.17 EGR31425.1 - 0.061 12.4 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NACHT PF05729.12 EGR31425.1 - 0.08 12.8 0.0 1.6 8.6 0.0 2.4 1 1 1 2 2 2 0 NACHT domain Torsin PF06309.11 EGR31425.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.5 1 0 0 1 1 1 0 Torsin ATPase_2 PF01637.18 EGR31425.1 - 0.2 11.6 3.5 1 9.2 0.0 2.9 3 1 1 4 4 4 0 ATPase domain predominantly from Archaea Ribosomal_S7 PF00177.21 EGR31426.1 - 8.8e-35 119.5 0.5 1.1e-34 119.2 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e FAM25 PF15825.5 EGR31426.1 - 0.026 14.8 0.0 7.4 7.0 0.0 2.4 2 0 0 2 2 2 0 FAM25 family Ribosomal_L29 PF00831.23 EGR31427.1 - 2.8e-13 49.6 1.6 2.8e-13 49.6 1.6 2.0 2 0 0 2 2 2 1 Ribosomal L29 protein HBM PF16591.5 EGR31427.1 - 0.023 14.1 4.1 0.027 13.9 4.1 1.1 1 0 0 1 1 1 0 Helical bimodular sensor domain WD40 PF00400.32 EGR31429.1 - 9.2e-20 70.6 3.5 0.00031 21.5 0.1 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR31429.1 - 1.5e-13 50.8 7.0 4.4e-05 23.7 0.2 4.3 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain ABC_membrane PF00664.23 EGR31429.1 - 1.7e-07 31.2 4.6 4.1e-07 29.9 4.7 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region eIF2A PF08662.11 EGR31429.1 - 5.5e-06 26.4 7.9 8.9e-05 22.4 2.3 2.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Virul_fac_BrkB PF03631.15 EGR31429.1 - 0.0028 17.3 0.1 0.01 15.4 0.1 1.8 2 0 0 2 2 2 1 Virulence factor BrkB Orf78 PF06024.12 EGR31429.1 - 0.1 12.9 1.0 0.24 11.7 1.0 1.6 1 0 0 1 1 1 0 Orf78 (ac78) ABC_tran PF00005.27 EGR31430.1 - 1.1e-07 32.5 0.1 1.5e-07 32.0 0.1 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGR31430.1 - 0.0015 18.1 5.0 0.0027 17.2 4.9 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EGR31430.1 - 0.059 13.6 0.2 0.64 10.3 0.2 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Peptidase_M8 PF01457.16 EGR31431.1 - 1.6e-42 145.9 7.5 5.1e-37 127.8 0.1 2.0 1 1 1 2 2 2 2 Leishmanolysin EGF_2 PF07974.13 EGR31431.1 - 0.0017 18.7 9.7 0.0017 18.7 9.7 4.1 4 1 0 4 4 4 1 EGF-like domain EGF_Tenascin PF18720.1 EGR31431.1 - 0.0039 17.2 4.4 0.012 15.6 4.4 2.0 1 0 0 1 1 1 1 Tenascin EGF domain Zincin_1 PF06262.11 EGR31431.1 - 0.15 12.2 0.1 0.3 11.2 0.1 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase WD40 PF00400.32 EGR31432.1 - 4.6e-07 30.4 12.0 0.71 10.9 0.6 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR31432.1 - 0.0009 19.5 5.4 19 5.6 0.0 5.9 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain ABC_tran PF00005.27 EGR31434.1 - 2.5e-26 92.8 0.1 2.5e-26 92.8 0.1 4.2 2 1 1 3 3 3 1 ABC transporter DUF4200 PF13863.6 EGR31434.1 - 1.8e-22 80.0 20.9 1.8e-22 80.0 20.9 7.4 7 1 2 9 9 9 1 Domain of unknown function (DUF4200) RsgA_GTPase PF03193.16 EGR31434.1 - 0.00016 21.6 0.1 0.00016 21.6 0.1 2.7 2 0 0 2 2 2 1 RsgA GTPase Arc_C PF18162.1 EGR31434.1 - 0.0057 16.5 8.7 0.12 12.3 0.3 4.0 3 0 0 3 3 3 2 Arc C-lobe MMR_HSR1 PF01926.23 EGR31434.1 - 0.017 15.2 0.9 0.19 11.8 0.1 3.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase ATP-synt_ab PF00006.25 EGR31434.1 - 0.032 13.9 0.0 0.053 13.2 0.0 1.4 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 EGR31434.1 - 0.11 12.3 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EGR31434.1 - 0.24 11.6 8.9 0.27 11.5 1.4 4.1 3 1 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 EGR31434.1 - 0.91 8.8 4.9 0.82 9.0 0.0 2.9 3 0 0 3 3 3 0 FtsK/SpoIIIE family ABC_tran PF00005.27 EGR31435.1 - 7.7e-16 58.9 0.1 1.7e-15 57.7 0.1 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EGR31435.1 - 9.1e-07 28.8 2.5 9.1e-07 28.8 2.5 2.2 1 1 1 2 2 2 1 ABC transporter transmembrane region AAA_29 PF13555.6 EGR31435.1 - 3.8e-05 23.3 0.1 0.00089 19.0 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGR31435.1 - 0.002 18.0 0.1 0.0035 17.3 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 EGR31435.1 - 0.002 17.6 2.8 0.0048 16.4 0.7 2.3 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGR31435.1 - 0.024 14.4 3.1 0.038 13.8 1.6 2.0 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGR31435.1 - 0.042 14.4 1.8 0.042 14.4 1.8 3.1 2 1 1 3 3 3 0 AAA domain AAA_11 PF13086.6 EGR31435.1 - 0.11 12.3 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rho_GDI PF02115.17 EGR31435.1 - 0.26 11.0 3.3 0.55 10.0 0.0 2.3 3 0 0 3 3 3 0 RHO protein GDP dissociation inhibitor CdiA_C_tRNase PF18664.1 EGR31435.1 - 0.31 11.2 2.2 0.31 11.2 0.3 1.9 2 0 0 2 2 2 0 CdiA C-terminal tRNase domain Ribosomal_S19 PF00203.21 EGR31436.1 - 1.3e-28 98.6 0.4 2.4e-28 97.8 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein S19 HEAT PF02985.22 EGR31437.1 - 7e-05 22.8 0.0 2.4 8.6 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 EGR31437.1 - 0.0023 18.3 0.0 1.1 9.7 0.0 3.3 3 1 0 3 3 3 1 HEAT repeats p25-alpha PF05517.12 EGR31437.1 - 0.095 12.9 0.7 0.19 11.9 0.7 1.4 1 0 0 1 1 1 0 p25-alpha tRNA-Thr_ED PF08915.11 EGR31437.1 - 0.33 11.0 2.5 2 8.5 0.4 2.4 1 1 1 2 2 2 0 Archaea-specific editing domain of threonyl-tRNA synthetase MORN PF02493.20 EGR31438.1 - 1.2e-68 223.1 115.0 9e-07 28.4 0.4 14.2 14 0 0 14 14 14 14 MORN repeat DUF5487 PF17589.2 EGR31438.1 - 0.0053 17.0 0.6 0.03 14.5 0.1 2.5 3 0 0 3 3 3 1 Family of unknown function (DUF5487) ETRAMP PF09716.10 EGR31439.1 - 0.22 11.6 3.8 0.29 11.2 3.8 1.1 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF1825 PF08855.10 EGR31441.1 - 0.0057 16.6 0.2 0.0057 16.6 0.2 2.4 4 0 0 4 4 4 1 Domain of unknown function (DUF1825) AI-2E_transport PF01594.16 EGR31441.1 - 0.12 11.5 1.5 0.17 11.0 1.5 1.2 1 0 0 1 1 1 0 AI-2E family transporter Erp_C PF06780.11 EGR31441.1 - 0.17 11.9 3.6 0.69 9.9 1.1 2.2 2 0 0 2 2 2 0 Erp protein C-terminus DUF4535 PF15054.6 EGR31441.1 - 0.23 11.2 1.6 0.39 10.5 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) WD40 PF00400.32 EGR31442.1 - 6.4e-28 96.4 11.8 3.9e-05 24.3 0.8 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR31442.1 - 5.7e-07 29.7 4.3 1 9.7 0.0 5.2 3 2 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGR31442.1 - 0.009 14.7 5.8 0.047 12.3 0.1 3.4 2 1 2 4 4 4 2 Nucleoporin Nup120/160 TB2_DP1_HVA22 PF03134.19 EGR31443.1 - 6.5e-27 93.3 2.7 6.5e-27 93.3 2.7 1.7 2 0 0 2 2 2 1 TB2/DP1, HVA22 family DUF2304 PF10066.9 EGR31443.1 - 0.032 14.4 7.1 0.043 14.0 1.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) Furin-like_2 PF15913.5 EGR31444.1 - 0.00089 19.4 12.7 0.00089 19.4 12.7 1.8 1 1 1 2 2 2 1 Furin-like repeat, cysteine-rich FYVE_2 PF02318.16 EGR31444.1 - 0.39 10.9 15.3 9.2 6.5 15.3 2.2 1 1 0 1 1 1 0 FYVE-type zinc finger AAA_6 PF12774.7 EGR31445.1 - 1.7e-161 536.6 0.7 4.4e-159 528.8 0.0 3.9 4 0 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGR31445.1 - 3.3e-119 398.6 17.6 3.3e-119 398.6 17.6 4.5 4 1 1 5 5 2 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 EGR31445.1 - 2.3e-105 352.2 0.0 5.8e-105 350.9 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EGR31445.1 - 1.3e-101 339.4 0.0 1.3e-101 339.4 0.0 2.8 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EGR31445.1 - 1.4e-84 282.7 0.9 1.4e-84 282.7 0.9 3.0 3 0 0 3 3 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 EGR31445.1 - 1.4e-72 243.1 0.8 6.6e-70 234.3 0.0 3.7 4 0 0 4 4 4 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGR31445.1 - 3.9e-58 195.9 0.1 3.6e-56 189.5 0.1 3.4 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGR31445.1 - 6.6e-47 158.5 0.0 1.6e-44 150.8 0.0 3.5 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain MT PF12777.7 EGR31445.1 - 2.6e-32 112.2 13.5 6.5e-32 110.9 13.5 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_AAA_lid PF17852.1 EGR31445.1 - 9.9e-28 96.8 2.4 5.8e-26 91.1 0.1 4.6 4 0 0 4 4 4 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 EGR31445.1 - 2.3e-18 66.2 0.2 3.1e-17 62.6 0.1 3.3 2 0 0 2 2 1 1 AAA+ lid domain AAA_5 PF07728.14 EGR31445.1 - 4.3e-14 52.7 0.0 0.00031 20.7 0.0 5.9 4 2 1 5 5 5 3 AAA domain (dynein-related subfamily) AAA PF00004.29 EGR31445.1 - 3e-09 37.4 8.0 0.069 13.6 0.0 7.2 7 1 1 8 8 7 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGR31445.1 - 1.9e-06 28.2 1.3 2.7 8.2 0.0 6.7 6 0 0 6 6 6 1 AAA domain AAA_18 PF13238.6 EGR31445.1 - 0.0014 19.1 0.1 0.6 10.7 0.0 4.3 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 EGR31445.1 - 0.0018 18.7 0.3 1.2 9.4 0.0 4.7 4 1 1 5 5 4 1 AAA ATPase domain RNA_helicase PF00910.22 EGR31445.1 - 0.0024 18.2 0.4 4.6 7.7 0.0 4.4 5 0 0 5 5 2 1 RNA helicase T2SSE PF00437.20 EGR31445.1 - 0.017 14.2 0.1 0.069 12.2 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_33 PF13671.6 EGR31445.1 - 0.021 15.0 0.0 26 5.0 0.0 4.0 4 0 0 4 4 4 0 AAA domain DUF2968 PF11180.8 EGR31445.1 - 0.022 14.4 2.2 0.058 13.0 2.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) AAA_30 PF13604.6 EGR31445.1 - 0.34 10.6 3.6 1.2 8.8 0.1 3.4 4 0 0 4 4 4 0 AAA domain Mg_chelatase PF01078.21 EGR31445.1 - 1.5 8.2 5.3 2.5 7.4 0.1 3.6 5 0 0 5 5 5 0 Magnesium chelatase, subunit ChlI DUF3450 PF11932.8 EGR31445.1 - 1.6 8.0 14.5 1.6 7.9 3.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) CbiA PF01656.23 EGR31445.1 - 2.2 8.3 6.7 17 5.5 0.1 4.6 5 1 0 5 5 4 0 CobQ/CobB/MinD/ParA nucleotide binding domain Myb_DNA-binding PF00249.31 EGR31446.1 - 1.6e-29 101.8 7.1 5.9e-18 64.8 0.6 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGR31446.1 - 1e-21 76.9 8.4 2.4e-17 62.9 1.4 2.6 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGR31446.1 - 3.5e-06 26.8 7.0 0.00015 21.6 0.5 2.8 2 1 1 3 3 3 2 Myb DNA-binding like SLIDE PF09111.10 EGR31446.1 - 0.00018 21.5 3.4 0.00065 19.7 0.5 2.4 1 1 1 2 2 2 1 SLIDE DTHCT PF08070.11 EGR31446.1 - 0.0019 18.9 1.8 0.0026 18.5 0.2 1.9 2 0 0 2 2 2 1 DTHCT (NUC029) region YfhD PF14151.6 EGR31446.1 - 7.3 6.8 8.4 18 5.6 8.4 1.8 1 0 0 1 1 1 0 YfhD-like protein tRNA-synt_2 PF00152.20 EGR31447.1 - 1e-82 277.7 0.7 1.3e-82 277.4 0.0 1.5 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGR31447.1 - 5.2e-06 26.4 0.2 4.5e-05 23.4 0.3 2.2 1 1 1 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGR31447.1 - 0.00041 19.9 0.0 0.0019 17.7 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) MFS_1 PF07690.16 EGR31448.1 - 0.0046 15.9 1.8 0.0046 15.9 1.8 1.8 1 1 0 2 2 2 1 Major Facilitator Superfamily Ribosomal_L21p PF00829.21 EGR31449.1 - 2.6e-15 56.5 0.6 2.6e-15 56.5 0.6 1.9 2 0 0 2 2 2 1 Ribosomal prokaryotic L21 protein PS_Dcarbxylase PF02666.15 EGR31450.1 - 7.3e-53 179.1 0.6 1e-52 178.6 0.6 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Biotin_lipoyl PF00364.22 EGR31450.1 - 0.02 14.7 0.1 0.059 13.2 0.1 1.8 1 0 0 1 1 1 0 Biotin-requiring enzyme DUF1344 PF07076.11 EGR31450.1 - 0.057 13.3 0.2 4.8 7.2 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1344) Biotin_lipoyl_2 PF13533.6 EGR31450.1 - 0.074 12.9 0.0 0.98 9.3 0.1 2.8 4 0 0 4 4 4 0 Biotin-lipoyl like WD40 PF00400.32 EGR31452.1 - 1.6e-17 63.5 1.8 0.003 18.4 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR31452.1 - 0.012 15.8 0.5 6.5 7.1 0.0 3.9 2 1 2 5 5 5 0 Anaphase-promoting complex subunit 4 WD40 domain TTL PF03133.15 EGR31453.1 - 4.8e-60 203.2 15.0 8.2e-60 202.4 15.0 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR31453.1 - 5.5e-06 25.8 6.2 0.0039 16.5 0.1 3.0 3 0 0 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR31453.1 - 0.00026 20.3 0.1 0.0014 18.0 0.0 2.2 2 1 0 2 2 2 1 Sugar-transfer associated ATP-grasp Porin_3 PF01459.22 EGR31454.1 - 0.013 14.9 2.2 0.025 14.1 0.4 2.2 1 1 0 1 1 1 0 Eukaryotic porin OMP_b-brl PF13505.6 EGR31454.1 - 0.14 12.3 4.8 0.18 11.9 2.4 2.0 1 1 1 2 2 2 0 Outer membrane protein beta-barrel domain GDPD PF03009.17 EGR31455.1 - 8.2e-22 78.2 0.1 1.9e-21 76.9 0.1 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family zf-CHY PF05495.12 EGR31458.1 - 2.4e-15 56.8 19.2 2.4e-15 56.8 19.2 2.8 2 1 0 2 2 2 1 CHY zinc finger Pkinase PF00069.25 EGR31459.1 - 7.3e-21 74.7 10.8 7.7e-12 45.1 4.5 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31459.1 - 6.1e-15 55.2 0.7 1.9e-08 33.9 1.8 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGR31459.1 - 4.9e-05 22.8 5.5 0.012 15.0 5.5 2.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR31459.1 - 0.0027 16.6 0.1 0.0027 16.6 0.1 2.1 2 0 0 2 2 2 1 Fungal protein kinase HBS1_N PF08938.10 EGR31459.1 - 0.052 13.9 3.3 0.13 12.6 0.3 2.6 2 1 0 2 2 2 0 HBS1 N-terminus Jagunal PF07086.12 EGR31459.1 - 0.64 10.1 12.1 1.5 8.9 12.0 1.7 1 1 0 1 1 1 0 Jagunal, ER re-organisation during oogenesis DUF1201 PF06716.11 EGR31459.1 - 6 7.0 7.5 0.98 9.5 0.5 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1201) Hist_deacetyl PF00850.19 EGR31460.1 - 1.1e-79 268.1 0.0 1.5e-79 267.7 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF4830 PF16112.5 EGR31460.1 - 0.11 12.9 1.4 0.2 12.2 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4830) H2O2_YaaD PF03883.14 EGR31460.1 - 0.12 11.9 0.5 0.71 9.3 0.1 2.1 2 0 0 2 2 2 0 Peroxide stress protein YaaA Sec20 PF03908.13 EGR31460.1 - 0.24 11.3 2.6 0.27 11.2 1.4 1.7 2 0 0 2 2 2 0 Sec20 zf-B_box PF00643.24 EGR31462.1 - 2e-07 31.0 6.9 2.6e-07 30.7 4.7 1.9 2 0 0 2 2 2 1 B-box zinc finger FYVE_2 PF02318.16 EGR31462.1 - 0.1 12.8 5.5 0.093 13.0 3.0 2.1 2 1 0 2 2 2 0 FYVE-type zinc finger Pkinase PF00069.25 EGR31463.1 - 4.1e-62 209.9 2.3 1.2e-61 208.4 0.5 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31463.1 - 5.2e-37 127.5 0.2 4.2e-36 124.5 0.1 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31463.1 - 4.7e-08 32.7 2.0 6.3e-08 32.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR31463.1 - 1.9e-05 23.7 0.0 3.7e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase DUF1926 PF09095.11 EGR31463.1 - 0.0006 19.5 1.7 0.006 16.2 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1926) APH PF01636.23 EGR31463.1 - 0.25 11.2 0.0 1.1 9.1 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Glu_cyclase_2 PF05096.12 EGR31464.1 - 9.1e-40 136.7 0.1 1e-39 136.5 0.1 1.0 1 0 0 1 1 1 1 Glutamine cyclotransferase DUF5074 PF16819.5 EGR31464.1 - 0.11 12.6 0.0 0.6 10.2 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5074) TilS_C PF11734.8 EGR31464.1 - 0.17 11.3 0.0 0.47 9.9 0.0 1.7 2 0 0 2 2 2 0 TilS substrate C-terminal domain ATP-synt_ab PF00006.25 EGR31465.1 - 5.7e-63 212.4 0.0 7.7e-63 212.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGR31465.1 - 1.3e-10 41.6 0.0 2.6e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF4556 PF15094.6 EGR31467.1 - 0.014 14.7 0.5 0.02 14.2 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4556) SUIM_assoc PF16619.5 EGR31467.1 - 0.67 10.1 12.0 1.3 9.1 12.0 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 YjbH PF06082.11 EGR31468.1 - 0.044 12.6 8.6 0.052 12.4 8.6 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH B9-C2 PF07162.11 EGR31469.1 - 5.1e-42 143.9 0.1 8.5e-42 143.2 0.1 1.4 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein Cir_N PF10197.9 EGR31469.1 - 1.6 9.0 5.7 0.74 10.1 2.6 2.0 2 0 0 2 2 2 0 N-terminal domain of CBF1 interacting co-repressor CIR CTP_synth_N PF06418.14 EGR31470.1 - 2.3e-101 338.5 0.2 3.2e-101 338.1 0.2 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EGR31470.1 - 2.6e-31 108.9 0.0 5e-31 107.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase class-I CbiA PF01656.23 EGR31470.1 - 0.0014 18.7 0.0 0.002 18.2 0.0 1.6 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain Peptidase_C26 PF07722.13 EGR31470.1 - 0.012 15.3 0.0 0.03 14.1 0.0 1.7 2 0 0 2 2 2 0 Peptidase C26 Pkinase PF00069.25 EGR31471.1 - 3.5e-63 213.4 2.0 4.8e-63 213.0 2.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31471.1 - 4.9e-26 91.6 0.1 6.9e-26 91.1 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR31471.1 - 6.6e-05 22.9 0.0 0.0019 18.1 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGR31471.1 - 0.00017 20.5 0.0 0.00028 19.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR31471.1 - 0.039 13.3 0.0 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Oxidored_FMN PF00724.20 EGR31474.1 - 9.1e-85 284.9 0.0 1.1e-84 284.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family AP_endonuc_2 PF01261.24 EGR31474.1 - 0.0002 20.9 0.0 0.0015 18.0 0.0 2.0 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Glyco_hydro_114 PF03537.13 EGR31474.1 - 0.11 11.8 0.0 1.1 8.5 0.0 2.1 2 0 0 2 2 2 0 Glycoside-hydrolase family GH114 DUF5532 PF17673.1 EGR31474.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5532) WD40 PF00400.32 EGR31475.1 - 2.8e-43 145.0 19.1 2.5e-07 31.3 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR31475.1 - 3.7e-17 62.4 0.1 0.0046 17.2 0.0 6.1 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGR31475.1 - 1.3e-07 31.7 0.9 0.21 11.5 0.0 3.6 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGR31475.1 - 2e-05 23.7 1.7 1.7 7.5 0.0 4.8 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EGR31475.1 - 0.00056 18.4 0.1 0.048 12.0 0.0 2.5 1 1 2 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz HPS3_N PF14761.6 EGR31475.1 - 0.064 12.8 0.0 0.49 9.9 0.0 2.2 1 1 1 2 2 2 0 Hermansky-Pudlak syndrome 3 TetM_leader PF08076.11 EGR31475.1 - 2.7 7.8 7.1 38 4.2 0.1 3.9 4 0 0 4 4 4 0 Tetracycline resistance determinant leader peptide PAF-AH_p_II PF03403.13 EGR31476.1 - 2.9e-38 131.4 8.7 6.4e-37 127.0 8.7 2.2 1 1 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 EGR31476.1 - 2.3e-13 49.7 0.0 4e-13 48.9 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 EGR31476.1 - 4e-12 45.8 0.1 7.5e-10 38.3 0.1 2.4 1 1 0 1 1 1 1 Chlorophyllase DLH PF01738.18 EGR31476.1 - 2.9e-10 40.1 0.0 5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 EGR31476.1 - 1.1e-08 35.0 0.0 4.9e-05 23.2 0.0 2.5 2 0 0 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGR31476.1 - 8.9e-08 31.7 0.0 0.0033 16.7 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_2 PF02230.16 EGR31476.1 - 0.00038 20.3 1.4 0.002 18.0 0.2 2.4 2 1 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 EGR31476.1 - 0.0004 20.1 0.0 0.05 13.2 0.0 2.3 2 0 0 2 2 2 1 alpha/beta hydrolase fold PGAP1 PF07819.13 EGR31476.1 - 0.0011 18.7 0.2 0.0021 17.8 0.2 1.6 1 0 0 1 1 1 1 PGAP1-like protein BAAT_C PF08840.11 EGR31476.1 - 0.014 15.4 0.1 0.04 13.8 0.0 1.8 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 EGR31476.1 - 0.031 14.9 0.0 0.053 14.1 0.0 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGR31476.1 - 0.078 12.4 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EGR31476.1 - 0.091 12.6 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lipase_3 PF01764.25 EGR31476.1 - 0.12 12.3 0.0 0.41 10.5 0.0 2.0 2 0 0 2 2 2 0 Lipase (class 3) Pkinase PF00069.25 EGR31477.1 - 2.1e-61 207.6 2.0 3.6e-61 206.8 2.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31477.1 - 3.4e-34 118.3 0.1 5.9e-34 117.5 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR31477.1 - 2.2e-07 30.2 2.7 2.2e-07 30.2 2.7 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EGR31477.1 - 8.4e-05 22.0 0.3 0.0012 18.3 0.1 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGR31477.1 - 0.00017 21.0 0.0 0.00066 19.1 0.0 1.9 1 1 1 2 2 2 1 Kinase-like MADF_DNA_bdg PF10545.9 EGR31477.1 - 0.37 11.1 6.0 0.35 11.2 2.6 2.4 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Pkinase_fungal PF17667.1 EGR31477.1 - 0.89 8.3 4.7 0.093 11.5 0.2 1.5 2 0 0 2 2 2 0 Fungal protein kinase Kelch_1 PF01344.25 EGR31478.1 - 8.4e-15 54.1 0.2 2.6e-10 39.7 0.0 4.2 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 EGR31478.1 - 9.5e-14 51.2 0.7 9.2e-06 25.6 0.0 4.5 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EGR31478.1 - 2.6e-12 46.5 1.7 0.00021 21.5 0.0 5.3 4 1 1 5 5 5 2 Kelch motif Kelch_3 PF13415.6 EGR31478.1 - 2.7e-07 30.7 0.3 1.4 9.3 0.0 4.8 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_2 PF07646.15 EGR31478.1 - 1.7e-06 27.8 0.0 0.097 12.7 0.0 3.0 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.6 EGR31478.1 - 0.00012 22.0 1.3 0.93 9.5 0.0 3.8 4 0 0 4 4 4 2 Kelch motif zf-B_box PF00643.24 EGR31478.1 - 0.18 12.0 1.2 0.53 10.5 1.2 1.7 1 0 0 1 1 1 0 B-box zinc finger Baculo_LEF-2 PF03041.14 EGR31478.1 - 0.33 10.6 7.0 0.12 12.0 0.8 2.5 1 1 0 2 2 2 0 lef-2 Herpes_UL32 PF06070.11 EGR31478.1 - 0.46 8.2 3.6 0.62 7.7 3.6 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 DnaJ_C PF01556.18 EGR31479.1 - 1.1e-35 122.8 1.5 1.8e-35 122.2 1.5 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EGR31479.1 - 1.1e-09 38.5 21.5 1.1e-09 38.5 21.5 2.1 2 0 0 2 2 2 1 DnaJ central domain Anti-TRAP PF15777.5 EGR31479.1 - 0.014 15.3 18.7 0.14 12.2 2.3 2.4 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein CDC13_N PF16853.5 EGR31479.1 - 0.07 12.7 6.2 0.099 12.2 6.2 1.3 1 0 0 1 1 1 0 Cell division control protein 13 N-terminus ALMT PF11744.8 EGR31479.1 - 0.11 11.3 1.4 0.14 11.0 1.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4175 PF13779.6 EGR31479.1 - 0.25 9.2 9.5 0.34 8.8 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4407 PF14362.6 EGR31479.1 - 3.3 7.0 5.0 0.89 8.9 2.4 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Pkinase PF00069.25 EGR31480.1 - 2.3e-61 207.5 1.6 3.1e-61 207.0 0.2 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31480.1 - 2e-40 138.7 0.1 3.7e-40 137.9 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 EGR31480.1 - 2.1e-29 98.8 25.6 2.2e-06 26.8 0.2 6.7 6 0 0 6 6 6 6 EF hand EF-hand_7 PF13499.6 EGR31480.1 - 3.9e-28 97.7 19.6 5.2e-10 39.6 0.4 5.9 3 1 3 6 6 6 5 EF-hand domain pair EF-hand_6 PF13405.6 EGR31480.1 - 8e-27 90.9 26.9 6.2e-05 22.6 0.1 6.9 6 0 0 6 6 6 6 EF-hand domain EF-hand_8 PF13833.6 EGR31480.1 - 1.4e-18 66.5 19.7 1.1e-05 25.1 0.1 6.7 5 2 2 7 7 7 6 EF-hand domain pair EF-hand_5 PF13202.6 EGR31480.1 - 7.2e-16 56.9 25.5 5.1e-06 25.7 0.0 6.2 6 0 0 6 6 6 5 EF hand SPARC_Ca_bdg PF10591.9 EGR31480.1 - 1.8e-07 31.5 7.7 0.068 13.5 0.3 3.9 4 0 0 4 4 4 3 Secreted protein acidic and rich in cysteine Ca binding region RST PF12174.8 EGR31480.1 - 3.6e-05 23.6 4.2 0.17 11.8 0.2 3.8 3 1 1 4 4 4 2 RCD1-SRO-TAF4 (RST) plant domain EF-hand_4 PF12763.7 EGR31480.1 - 0.0007 19.5 13.8 0.23 11.4 0.5 4.9 1 1 2 5 5 5 2 Cytoskeletal-regulatory complex EF hand ABC1 PF03109.16 EGR31480.1 - 0.014 15.5 1.4 0.8 9.9 0.0 3.6 4 1 1 5 5 5 0 ABC1 family EF-hand_9 PF14658.6 EGR31480.1 - 0.047 14.0 0.4 4.7 7.6 0.0 3.6 4 0 0 4 4 4 0 EF-hand domain APH PF01636.23 EGR31480.1 - 0.063 13.2 0.0 0.17 11.8 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGR31480.1 - 0.069 12.5 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Clr5 PF14420.6 EGR31480.1 - 0.11 12.8 2.4 27 5.1 0.0 3.5 3 0 0 3 3 3 0 Clr5 domain EF-hand_11 PF08976.11 EGR31480.1 - 0.16 12.9 2.3 7.8 7.4 0.1 3.8 3 1 1 4 4 4 0 EF-hand domain p25-alpha PF05517.12 EGR31480.1 - 0.19 11.9 17.0 0.84 9.8 0.5 4.7 2 1 4 6 6 6 0 p25-alpha EF-hand_10 PF14788.6 EGR31480.1 - 0.26 11.2 23.0 0.98 9.3 0.2 6.5 5 2 2 7 7 7 0 EF hand DUF3006 PF11213.8 EGR31481.1 - 0.022 15.0 0.1 0.059 13.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3006) CAP PF00188.26 EGR31482.1 - 0.028 15.3 0.0 0.028 15.3 0.0 2.3 2 1 0 2 2 2 0 Cysteine-rich secretory protein family Herpes_gE PF02480.16 EGR31482.1 - 0.062 12.1 0.0 0.089 11.5 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Glycos_trans_3N PF02885.17 EGR31482.1 - 0.16 11.8 0.1 0.34 10.8 0.1 1.5 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain DUF4201 PF13870.6 EGR31483.1 - 4.8e-38 130.7 38.4 4.8e-38 130.7 38.4 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4201) UPF0242 PF06785.11 EGR31483.1 - 0.0008 19.6 15.6 0.0008 19.6 15.6 3.6 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0242) N-terminus XhlA PF10779.9 EGR31483.1 - 0.15 12.3 0.4 0.15 12.3 0.4 5.3 6 0 0 6 6 6 0 Haemolysin XhlA HALZ PF02183.18 EGR31483.1 - 0.2 11.9 25.5 0.56 10.5 1.1 5.3 4 1 0 4 4 4 0 Homeobox associated leucine zipper MAPEG PF01124.18 EGR31484.1 - 4.7e-08 33.0 0.1 5.8e-08 32.7 0.1 1.2 1 0 0 1 1 1 1 MAPEG family MASE3 PF17159.4 EGR31484.1 - 0.012 15.2 1.7 0.36 10.4 1.7 2.1 1 1 0 1 1 1 0 Membrane-associated sensor domain Pyridoxal_deC PF00282.19 EGR31485.1 - 1.8e-20 73.0 0.0 5.2e-20 71.5 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGR31485.1 - 1.8e-09 37.1 0.0 5.1e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGR31485.1 - 0.053 12.8 0.0 0.17 11.1 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase PWI PF01480.17 EGR31485.1 - 0.13 12.6 0.1 1.2 9.5 0.0 2.6 3 0 0 3 3 3 0 PWI domain Folliculin PF11704.8 EGR31485.1 - 0.17 11.8 0.6 2 8.3 0.3 2.2 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport TPR_2 PF07719.17 EGR31486.1 - 1.2e-10 40.6 4.6 7e-06 25.8 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGR31486.1 - 4.3e-08 32.6 9.1 8.6e-07 28.5 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGR31486.1 - 7.4e-08 32.0 3.9 1.1e-05 25.2 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGR31486.1 - 4e-06 27.2 0.4 5.2e-05 23.7 0.0 2.5 2 1 1 3 3 2 1 Tetratricopeptide repeat FKBP_C PF00254.28 EGR31486.1 - 4.1e-05 23.8 0.0 9e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Fis1_TPR_C PF14853.6 EGR31486.1 - 9.4e-05 22.4 5.5 0.24 11.5 0.0 3.9 2 2 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 EGR31486.1 - 9.9e-05 22.4 0.0 0.00019 21.5 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF3856 PF12968.7 EGR31486.1 - 0.0015 18.6 0.4 0.0058 16.7 0.4 1.9 1 1 0 1 1 1 1 Domain of Unknown Function (DUF3856) TPR_19 PF14559.6 EGR31486.1 - 0.0048 17.4 0.5 0.0048 17.4 0.5 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGR31486.1 - 0.02 14.6 4.1 0.21 11.3 0.0 3.3 2 1 1 3 3 3 0 TPR repeat YqaH PF17448.2 EGR31486.1 - 0.03 14.6 0.1 0.092 13.1 0.1 1.9 1 1 0 1 1 1 0 Uncharacterized YqaH-like RabGAP-TBC PF00566.18 EGR31486.1 - 0.042 13.5 3.9 0.083 12.5 3.9 1.5 1 0 0 1 1 1 0 Rab-GTPase-TBC domain TPR_17 PF13431.6 EGR31486.1 - 0.068 13.6 3.0 6.9 7.3 0.3 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat FAD_binding_7 PF03441.14 EGR31487.1 - 5.6e-66 221.9 0.3 1.1e-65 220.9 0.3 1.5 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase cNMP_binding PF00027.29 EGR31487.1 - 1.5e-23 82.6 0.0 1.1e-15 57.4 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Lactamase_B_2 PF12706.7 EGR31487.1 - 4.3e-05 23.1 0.0 0.00018 21.1 0.0 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGR31487.1 - 9.5e-05 22.5 0.0 0.00026 21.0 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 EGR31487.1 - 0.035 14.0 0.0 0.071 13.0 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain Alpha-amylase_C PF02806.18 EGR31488.1 - 7.7e-19 68.0 0.0 2.3e-18 66.5 0.0 1.9 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 EGR31488.1 - 1.8e-14 54.0 2.8 4.1e-12 46.3 1.0 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 EGR31488.1 - 4e-14 52.7 0.3 1.1e-13 51.3 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) AMPK1_CBM PF16561.5 EGR31488.1 - 0.0022 18.2 0.0 0.0077 16.4 0.0 2.0 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase cNMP_binding PF00027.29 EGR31489.1 - 4.6e-28 97.1 0.0 1.3e-15 57.2 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Lactamase_B_2 PF12706.7 EGR31489.1 - 5e-05 22.9 0.0 0.00018 21.1 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGR31489.1 - 0.00065 19.8 0.2 0.0037 17.3 0.2 2.2 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Nucleoside_tran PF01733.18 EGR31490.1 - 6.4e-14 52.0 10.6 7.2e-14 51.9 10.6 1.1 1 0 0 1 1 1 1 Nucleoside transporter ABC2_membrane_2 PF12679.7 EGR31490.1 - 0.36 10.1 7.2 0.14 11.4 3.7 2.0 2 1 0 2 2 2 0 ABC-2 family transporter protein Pkinase PF00069.25 EGR31491.1 - 4.8e-74 249.1 0.2 5.7e-74 248.8 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31491.1 - 3.4e-42 144.5 0.0 4.4e-42 144.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31491.1 - 1.1e-11 44.6 0.0 2e-10 40.5 0.0 2.1 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR31491.1 - 1.5e-06 27.3 0.2 3.6e-06 26.0 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGR31491.1 - 0.18 11.7 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Antimicrobial_1 PF08018.11 EGR31491.1 - 5.7 7.2 5.7 27 5.0 0.7 2.5 2 0 0 2 2 2 0 Frog antimicrobial peptide S10_plectin PF03501.15 EGR31492.1 - 1.1e-28 99.2 0.1 1.4e-28 98.8 0.1 1.1 1 0 0 1 1 1 1 Plectin/S10 domain TrmB PF01978.19 EGR31492.1 - 0.021 14.7 0.0 0.07 13.0 0.0 1.9 1 1 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB RYDR_ITPR PF01365.21 EGR31493.1 - 6.6e-07 28.9 6.7 6.6e-07 28.9 6.7 4.3 3 1 0 4 4 4 2 RIH domain UQ_con PF00179.26 EGR31495.1 - 1.1e-42 145.0 0.7 1.2e-42 144.8 0.7 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase PF00069.25 EGR31496.1 - 1.6e-54 185.0 0.6 2.2e-54 184.6 0.6 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31496.1 - 2.1e-30 105.9 0.1 2.9e-30 105.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR31496.1 - 4.9e-06 26.6 0.0 0.05 13.5 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pox_ser-thr_kin PF05445.11 EGR31496.1 - 0.00078 18.5 10.4 0.0019 17.3 10.0 1.8 1 1 1 2 2 2 1 Poxvirus serine/threonine protein kinase Kdo PF06293.14 EGR31496.1 - 0.00087 18.7 0.2 0.0016 17.8 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EGR31496.1 - 0.0091 15.5 0.4 0.015 14.9 0.4 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 EGR31496.1 - 0.022 13.5 0.0 0.022 13.5 0.0 1.3 1 1 0 1 1 1 0 Fungal protein kinase LupA PF18242.1 EGR31496.1 - 0.025 14.2 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Legionella ubiquitin-specific protease A domain CDC50 PF03381.15 EGR31497.1 - 1.3e-30 106.8 0.4 1.5e-30 106.6 0.4 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF2370 PF10176.9 EGR31497.1 - 0.07 12.8 0.0 0.071 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) CAP PF00188.26 EGR31498.1 - 0.00024 21.9 3.8 0.053 14.4 0.5 2.8 2 1 1 3 3 3 2 Cysteine-rich secretory protein family Dec-1 PF04624.14 EGR31498.1 - 2.9 7.8 6.4 6 6.8 6.4 1.5 1 0 0 1 1 1 0 Dec-1 repeat Pkinase PF00069.25 EGR31500.1 - 9.4e-66 221.9 0.1 1.2e-65 221.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31500.1 - 7.5e-34 117.2 0.0 1e-33 116.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31500.1 - 5.7e-05 22.6 0.1 0.00015 21.2 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR31500.1 - 0.00024 20.0 0.0 0.00049 19.0 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EGR31500.1 - 0.01 14.9 0.0 0.021 13.9 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 NIF PF03031.18 EGR31502.1 - 1.6e-50 170.9 2.7 2e-50 170.6 2.7 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Acid_phosphat_B PF03767.14 EGR31502.1 - 0.012 15.2 0.5 0.017 14.7 0.5 1.2 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) LRR_6 PF13516.6 EGR31503.1 - 1.1e-16 59.4 28.7 0.0057 16.6 0.0 11.8 13 0 0 13 13 13 5 Leucine Rich repeat LRR_4 PF12799.7 EGR31503.1 - 1.1e-07 32.1 37.5 0.017 15.6 3.2 8.7 5 2 4 9 9 9 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGR31503.1 - 0.04 14.5 21.3 19 6.3 0.1 9.4 10 0 0 10 10 10 0 Leucine Rich Repeat SAM_2 PF07647.17 EGR31503.1 - 0.13 12.4 5.2 0.54 10.4 0.2 3.3 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) LRR_8 PF13855.6 EGR31503.1 - 0.82 9.5 30.8 12 5.7 0.3 7.1 3 3 2 5 5 5 0 Leucine rich repeat MORN PF02493.20 EGR31504.1 - 1.3e-09 37.4 39.0 0.0071 16.2 0.2 8.6 9 1 0 9 9 9 6 MORN repeat DUF667 PF05018.13 EGR31505.1 - 4.2e-91 303.7 1.0 4.7e-91 303.5 1.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) CTK3 PF12243.8 EGR31506.1 - 0.2 11.7 4.9 0.26 11.3 4.9 1.3 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Band_7 PF01145.25 EGR31507.1 - 2.5e-26 92.8 0.4 2.5e-26 92.8 0.4 2.3 1 1 0 2 2 2 1 SPFH domain / Band 7 family Band_7_C PF16200.5 EGR31507.1 - 2.3e-12 46.8 0.2 4.9e-12 45.7 0.2 1.6 1 0 0 1 1 1 1 C-terminal region of band_7 FWWh PF14922.6 EGR31508.1 - 1e-06 28.8 5.6 1e-06 28.8 5.6 1.9 1 1 1 2 2 2 1 Protein of unknown function Nit_Regul_Hom PF10126.9 EGR31508.1 - 0.044 13.8 0.8 0.079 13.0 0.2 1.9 2 1 0 2 2 2 0 Uncharacterized protein, homolog of nitrogen regulatory protein PII DUF3774 PF12609.8 EGR31509.1 - 2.9 9.0 7.5 23 6.1 6.8 2.7 1 1 0 1 1 1 0 Wound-induced protein NDK PF00334.19 EGR31510.1 - 7.5e-74 246.2 0.0 5.1e-41 139.9 0.0 2.2 2 0 0 2 2 2 2 Nucleoside diphosphate kinase DUF1126 PF06565.12 EGR31510.1 - 0.0036 17.1 0.9 0.01 15.6 0.9 1.8 1 1 0 1 1 1 1 DUF1126 PH-like domain 4HBT PF03061.22 EGR31511.1 - 5.1e-10 39.6 0.0 6.4e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.6 EGR31511.1 - 0.0091 16.3 0.0 0.011 16.0 0.0 1.1 1 0 0 1 1 1 1 Thioesterase-like superfamily Phlebovirus_G1 PF07243.11 EGR31511.1 - 0.0092 14.4 0.2 0.015 13.7 0.1 1.4 1 1 1 2 2 2 1 Phlebovirus glycoprotein G1 PP2C PF00481.21 EGR31512.1 - 2.5e-38 132.2 0.0 3e-38 132.0 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGR31512.1 - 0.00095 18.9 0.0 0.0044 16.7 0.0 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGR31512.1 - 0.008 16.1 0.0 0.045 13.7 0.0 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Hist_deacetyl PF00850.19 EGR31513.1 - 0.078 12.4 0.7 0.13 11.7 0.7 1.4 1 0 0 1 1 1 0 Histone deacetylase domain DUF1599 PF07659.11 EGR31513.1 - 0.16 12.4 3.3 2.9 8.4 0.0 3.2 3 0 0 3 3 3 0 Nucleotide modification associated domain 1 Aldedh PF00171.22 EGR31514.1 - 5.9e-168 559.1 0.0 6.6e-168 559.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EGR31514.1 - 0.083 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1487) DUF5446 PF17522.2 EGR31514.1 - 0.21 11.8 0.5 0.49 10.6 0.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5446) cNMP_binding PF00027.29 EGR31515.1 - 7.3e-14 51.6 0.1 1.8e-08 34.4 0.0 2.1 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Tricorn_PDZ PF14685.6 EGR31515.1 - 0.16 12.0 0.0 0.31 11.0 0.0 1.5 1 0 0 1 1 1 0 Tricorn protease PDZ domain Vps39_2 PF10367.9 EGR31516.1 - 0.011 16.2 0.2 0.043 14.3 0.2 2.1 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 HypA PF01155.19 EGR31516.1 - 0.071 13.1 0.1 0.071 13.1 0.1 2.7 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA VATC PF18716.1 EGR31516.1 - 0.36 10.7 4.9 1.1 9.2 4.9 1.8 1 0 0 1 1 1 0 Vms1-associating treble clef domain IGR PF09597.10 EGR31519.1 - 4.9e-20 71.4 0.5 7.9e-20 70.7 0.5 1.4 1 0 0 1 1 1 1 IGR protein motif E2F_CC-MB PF16421.5 EGR31519.1 - 0.096 13.1 0.1 0.33 11.3 0.1 1.9 1 1 1 2 2 2 0 E2F transcription factor CC-MB domain CoA_trans PF01144.23 EGR31520.1 - 1.4e-88 296.0 3.1 3.1e-63 213.1 0.3 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 EGR31520.1 - 0.0023 16.3 0.0 0.0033 15.8 0.0 1.1 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter CLIP_SPH_mas PF18398.1 EGR31521.1 - 0.033 14.6 0.2 0.059 13.8 0.2 1.4 1 0 0 1 1 1 0 Clip-domain serine protease homolog masquerade DUF736 PF05284.12 EGR31522.1 - 0.1 12.5 0.0 0.56 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF736) SNF2_N PF00176.23 EGR31523.1 - 2.3e-24 85.8 0.5 2.3e-24 85.8 0.5 2.3 2 1 0 2 2 2 1 SNF2 family N-terminal domain NUP50 PF08911.11 EGR31523.1 - 0.016 15.9 2.4 0.042 14.5 2.4 1.7 1 0 0 1 1 1 0 NUP50 (Nucleoporin 50 kDa) CRF1 PF10380.9 EGR31523.1 - 1.1 9.7 5.9 16 5.9 1.1 2.7 2 0 0 2 2 2 0 Transcription factor CRF1 Neural_ProG_Cyt PF06567.11 EGR31524.1 - 0.0064 16.7 0.7 0.0064 16.7 0.7 1.5 2 0 0 2 2 2 1 Neural chondroitin sulphate proteoglycan cytoplasmic domain LVIVD PF08309.11 EGR31524.1 - 0.28 10.6 1.9 0.75 9.2 0.4 2.3 2 0 0 2 2 2 0 LVIVD repeat Snf7 PF03357.21 EGR31525.1 - 7.7e-22 77.7 40.3 9.6e-22 77.4 38.6 2.0 1 1 1 2 2 2 1 Snf7 YvrJ PF12841.7 EGR31525.1 - 0.0019 17.7 1.2 0.0049 16.4 1.2 1.7 1 0 0 1 1 1 1 YvrJ protein family DUF1192 PF06698.11 EGR31525.1 - 0.05 13.7 1.9 0.086 12.9 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DUF948 PF06103.11 EGR31525.1 - 0.21 11.9 0.3 0.21 11.9 0.3 3.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) CBM-like PF14683.6 EGR31525.1 - 0.78 9.6 5.1 5.5 6.8 1.4 2.3 2 1 0 2 2 2 0 Polysaccharide lyase family 4, domain III DUF4094 PF13334.6 EGR31525.1 - 4.1 7.9 20.8 1.1 9.7 4.3 3.7 1 1 3 4 4 4 0 Domain of unknown function (DUF4094) Merozoite_SPAM PF07133.11 EGR31525.1 - 6.3 6.8 33.2 1.2 9.1 15.8 2.3 1 1 0 2 2 2 0 Merozoite surface protein (SPAM) Phosphodiest PF01663.22 EGR31528.1 - 5.3e-09 36.1 0.2 1e-08 35.2 0.2 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Metalloenzyme PF01676.18 EGR31528.1 - 5.8e-08 32.4 0.1 8.6e-08 31.8 0.1 1.3 1 0 0 1 1 1 1 Metalloenzyme superfamily Sulfatase PF00884.23 EGR31528.1 - 0.067 12.6 0.2 0.12 11.8 0.2 1.2 1 0 0 1 1 1 0 Sulfatase Gp_dh_C PF02800.20 EGR31528.1 - 0.15 11.6 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain PIH1_CS PF18201.1 EGR31529.1 - 1.6e-07 31.6 2.6 2.2e-07 31.2 0.4 2.4 2 0 0 2 2 2 1 PIH1 CS-like domain ABC_tran PF00005.27 EGR31530.1 - 1.4e-31 109.8 2.4 2.5e-31 109.0 0.1 2.6 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 EGR31530.1 - 3.4e-12 46.8 0.6 3.5e-07 30.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGR31530.1 - 0.00043 19.8 1.1 0.0024 17.3 0.2 2.5 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain Imm3 PF14425.6 EGR31530.1 - 0.0005 20.1 4.9 0.12 12.4 0.1 3.0 2 0 0 2 2 2 2 Immunity protein Imm3 RsgA_GTPase PF03193.16 EGR31530.1 - 0.0029 17.5 0.0 0.011 15.6 0.0 2.1 1 0 0 1 1 1 1 RsgA GTPase AAA_23 PF13476.6 EGR31530.1 - 0.017 15.6 1.9 0.017 15.6 1.9 4.7 3 2 2 5 5 5 0 AAA domain AAA_29 PF13555.6 EGR31530.1 - 0.022 14.5 0.2 0.058 13.2 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 EGR31530.1 - 0.066 12.6 0.1 0.21 10.9 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 EGR31530.1 - 0.16 11.0 0.2 0.47 9.5 0.1 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein Cpn60_TCP1 PF00118.24 EGR31531.1 - 2.7e-88 296.8 16.7 4e-88 296.2 16.7 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family MORN PF02493.20 EGR31532.1 - 1.4e-27 93.9 37.9 7e-06 25.6 3.7 6.3 6 0 0 6 6 6 6 MORN repeat zf-C3HC4_4 PF15227.6 EGR31533.1 - 5.9e-10 39.2 10.2 3.4e-09 36.7 10.7 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EGR31533.1 - 1.6e-08 34.4 12.2 4.6e-08 33.0 7.9 2.4 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGR31533.1 - 3.9e-07 29.8 13.8 7.4e-07 28.9 13.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGR31533.1 - 5.9e-07 29.4 14.2 2.4e-06 27.4 14.4 2.0 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGR31533.1 - 7.6e-07 28.9 14.3 1.7e-06 27.8 14.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGR31533.1 - 7.9e-07 29.3 12.9 1.3e-06 28.6 12.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGR31533.1 - 4e-06 26.6 11.2 8e-06 25.6 11.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EGR31533.1 - 0.00042 20.1 4.9 0.00063 19.6 4.9 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 EGR31533.1 - 0.0098 15.7 14.7 0.21 11.4 15.3 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 U-box PF04564.15 EGR31533.1 - 0.057 13.6 0.0 0.097 12.9 0.0 1.4 1 0 0 1 1 1 0 U-box domain zf-RING_10 PF16685.5 EGR31533.1 - 0.093 12.9 11.9 0.065 13.4 9.9 1.9 1 1 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EGR31533.1 - 0.29 10.9 8.0 0.3 10.9 5.6 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EGR31533.1 - 0.35 11.2 13.5 0.1 12.9 7.4 2.3 1 1 0 2 2 2 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGR31533.1 - 0.56 10.3 6.2 0.85 9.7 5.5 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 EGR31533.1 - 0.95 9.3 9.2 2.1 8.2 9.2 1.6 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 EGR31533.1 - 3.1 7.6 10.2 3 7.7 7.0 2.6 2 1 0 2 2 2 0 RING-like zinc finger zf-H2C2_2 PF13465.6 EGR31533.1 - 4 8.0 6.6 59 4.3 0.0 2.9 2 1 0 2 2 2 0 Zinc-finger double domain SDP_N PF12278.8 EGR31533.1 - 6.2 7.0 6.3 4.4 7.4 4.7 1.5 1 1 1 2 2 2 0 Sex determination protein N terminal Auto_anti-p27 PF06677.12 EGR31533.1 - 9.6 6.5 8.9 12 6.2 0.1 2.5 2 0 0 2 2 2 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) TTL PF03133.15 EGR31534.1 - 6.2e-29 101.0 8.0 6.2e-29 101.0 8.0 1.9 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR31534.1 - 0.0096 15.2 0.0 0.0096 15.2 0.0 3.1 3 0 0 3 3 3 1 YheC/D like ATP-grasp HTH_Tnp_Tc5 PF03221.16 EGR31536.1 - 4.2e-13 49.1 0.5 7.1e-13 48.4 0.5 1.4 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain CPBP PF02517.16 EGR31537.1 - 0.0013 19.1 19.5 0.0062 16.9 19.5 2.2 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease EF-hand_7 PF13499.6 EGR31538.1 - 2.3e-06 28.0 11.5 0.0014 19.1 0.2 5.3 4 2 1 5 5 5 3 EF-hand domain pair EF-hand_13 PF17958.1 EGR31538.1 - 0.0003 20.6 0.1 0.0011 18.7 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain EF-hand_6 PF13405.6 EGR31538.1 - 0.075 13.0 14.1 7.6 6.8 0.1 6.1 6 0 0 6 6 6 0 EF-hand domain NDUF_B7 PF05676.13 EGR31539.1 - 0.00065 19.4 1.4 0.014 15.1 0.0 2.2 2 0 0 2 2 2 2 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) COX6B PF02297.17 EGR31539.1 - 0.013 15.7 1.0 0.024 14.9 1.0 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb TTL PF03133.15 EGR31540.1 - 1e-09 38.0 0.9 1e-09 38.0 0.9 1.7 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family NLPC_P60 PF00877.19 EGR31540.1 - 0.0016 18.5 0.0 0.0052 16.8 0.0 2.0 1 0 0 1 1 1 1 NlpC/P60 family Pkinase PF00069.25 EGR31541.1 - 3.2e-75 252.9 2.0 4.1e-75 252.5 2.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31541.1 - 1.7e-38 132.4 0.3 2.3e-38 132.0 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31541.1 - 5e-10 39.2 1.0 1.8e-09 37.4 1.0 1.8 1 1 1 2 2 2 1 Kinase-like FTA2 PF13095.6 EGR31541.1 - 0.0026 17.4 1.7 1.2 8.7 0.3 2.4 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Dapper PF15268.6 EGR31542.1 - 1.2 7.9 19.9 1.4 7.7 19.9 1.1 1 0 0 1 1 1 0 Dapper Equine_IAV_S2 PF06502.11 EGR31543.1 - 0.15 12.1 0.4 0.28 11.3 0.4 1.5 1 0 0 1 1 1 0 Equine infectious anaemia virus S2 protein HA2 PF04408.23 EGR31544.1 - 2.9e-23 82.2 0.0 5.8e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGR31544.1 - 1.4e-19 70.2 0.0 3.4e-19 69.0 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGR31544.1 - 3.4e-16 59.6 0.1 7.6e-16 58.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGR31544.1 - 0.0074 16.1 0.1 0.014 15.2 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase LRR_4 PF12799.7 EGR31545.1 - 0.00013 22.2 32.7 0.0016 18.8 5.1 5.3 3 1 1 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGR31545.1 - 0.011 15.5 1.1 0.011 15.5 1.1 4.5 6 0 0 6 6 6 0 Leucine rich repeat LRR_6 PF13516.6 EGR31545.1 - 0.85 9.8 3.0 4.8 7.5 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 EGR31545.1 - 5 8.1 8.8 1.3e+02 3.8 4.1 4.7 2 1 0 2 2 2 0 Leucine Rich Repeat WD40 PF00400.32 EGR31546.1 - 0.13 13.2 0.0 10 7.2 0.0 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat SecY PF00344.20 EGR31547.1 - 4.8e-64 216.5 14.9 6.9e-64 216.0 14.9 1.2 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EGR31547.1 - 1.2e-17 63.5 0.2 1.2e-17 63.5 0.2 2.1 2 0 0 2 2 2 1 Plug domain of Sec61p DUF1430 PF07242.11 EGR31547.1 - 0.028 14.7 7.3 5.6 7.3 0.0 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1430) Cyc-maltodext_C PF10438.9 EGR31548.1 - 0.22 11.7 2.3 1.9 8.6 0.4 2.8 2 1 0 2 2 2 0 Cyclo-malto-dextrinase C-terminal domain MatE PF01554.18 EGR31550.1 - 2.2e-34 118.4 30.6 6.8e-19 68.1 8.0 2.9 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EGR31550.1 - 1.4e-07 31.6 4.3 1.4e-07 31.6 4.3 3.5 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain Ion_trans PF00520.31 EGR31551.1 - 9.8e-182 601.3 157.9 4.2e-60 203.0 27.7 5.4 6 0 0 6 6 6 4 Ion transport protein PKD_channel PF08016.12 EGR31551.1 - 1.5e-05 23.9 14.3 1.5e-05 23.9 14.3 12.2 7 4 4 11 11 11 7 Polycystin cation channel GPHH PF16905.5 EGR31551.1 - 5.6e-05 22.8 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated COX16 PF14138.6 EGR31551.1 - 0.01 16.3 1.3 6 7.5 0.0 3.3 3 0 0 3 3 3 0 Cytochrome c oxidase assembly protein COX16 Selenoprotein_S PF06936.11 EGR31551.1 - 2.9 7.7 6.5 0.35 10.7 0.2 2.7 3 0 0 3 3 3 0 Selenoprotein S (SelS) PhoR PF11808.8 EGR31552.1 - 0.039 14.4 0.3 0.15 12.5 0.3 2.0 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR Apq12 PF12716.7 EGR31552.1 - 0.72 9.8 9.8 2.1 8.4 9.8 1.8 1 0 0 1 1 1 0 Nuclear pore assembly and biogenesis G0-G1_switch_2 PF15103.6 EGR31552.1 - 9.3 6.7 14.4 2.1 8.8 0.2 2.4 2 0 0 2 2 2 0 G0/G1 switch protein 2 Cation_ATPase_N PF00690.26 EGR31553.1 - 2.3 8.0 7.0 8.1 6.2 0.1 4.2 4 0 0 4 4 4 0 Cation transporter/ATPase, N-terminus UCH PF00443.29 EGR31554.1 - 7.2e-11 42.1 1.0 7.7e-11 42.0 1.0 1.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Semialdhyde_dhC PF02774.18 EGR31554.1 - 0.037 14.1 0.0 0.06 13.4 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain DUF440 PF04269.12 EGR31554.1 - 0.046 14.0 0.4 0.28 11.5 0.4 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF440 APG12 PF04110.13 EGR31554.1 - 0.088 13.2 0.4 0.24 11.8 0.3 1.8 1 1 1 2 2 2 0 Ubiquitin-like autophagy protein Apg12 DNA_pol_E_B PF04042.16 EGR31555.1 - 0.027 13.8 0.2 0.097 12.0 0.2 1.8 2 0 0 2 2 2 0 DNA polymerase alpha/epsilon subunit B FAD_binding_2 PF00890.24 EGR31556.1 - 5.5e-117 391.4 3.3 7e-117 391.0 3.3 1.1 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EGR31556.1 - 3.5e-40 136.9 0.5 5.2e-40 136.4 0.5 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 EGR31556.1 - 0.00052 19.3 0.1 0.043 13.0 0.1 2.5 3 0 0 3 3 3 1 Thi4 family Pyr_redox_2 PF07992.14 EGR31556.1 - 0.001 18.4 0.1 0.0024 17.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGR31556.1 - 0.0012 18.1 3.9 0.046 13.0 0.2 3.3 3 1 0 3 3 3 1 FAD binding domain GIDA PF01134.22 EGR31556.1 - 0.04 13.0 1.9 0.15 11.1 1.4 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A DAO PF01266.24 EGR31556.1 - 0.075 12.6 0.1 0.33 10.5 0.1 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase Synaptobrevin PF00957.21 EGR31557.1 - 5.3e-22 77.4 10.4 5.3e-22 77.4 10.4 1.6 2 0 0 2 2 2 1 Synaptobrevin Longin PF13774.6 EGR31557.1 - 5.4e-19 68.0 2.4 5.4e-19 68.0 2.4 1.9 3 0 0 3 3 3 1 Regulated-SNARE-like domain Peptidase_C50 PF03568.17 EGR31557.1 - 0.078 12.1 2.3 0.12 11.5 2.3 1.2 1 0 0 1 1 1 0 Peptidase family C50 DUF3755 PF12579.8 EGR31557.1 - 5.7 6.7 7.6 6.7 6.5 2.0 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3755) ThiF PF00899.21 EGR31558.1 - 2.9e-61 207.0 0.0 4.2e-61 206.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EGR31558.1 - 1.7e-06 28.5 0.3 1e-05 26.0 0.1 2.3 3 0 0 3 3 2 1 Rhodanese-like domain 2-Hacid_dh_C PF02826.19 EGR31558.1 - 9.1e-05 21.9 0.6 0.0043 16.4 0.2 2.2 1 1 1 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EGR31558.1 - 0.0021 18.1 0.1 0.0089 16.1 0.0 2.1 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EGR31558.1 - 0.0069 16.6 0.1 0.018 15.3 0.1 1.7 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 EGR31558.1 - 0.013 14.8 0.0 0.031 13.5 0.0 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGR31558.1 - 0.027 14.0 0.1 0.039 13.5 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EGR31558.1 - 0.041 14.3 0.0 0.32 11.4 0.0 2.2 1 1 0 1 1 1 0 Putative NAD(P)-binding PglD_N PF17836.1 EGR31558.1 - 0.043 14.5 0.9 0.043 14.5 0.9 2.5 3 0 0 3 3 2 0 PglD N-terminal domain AlaDh_PNT_C PF01262.21 EGR31558.1 - 0.059 12.6 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_3 PF13738.6 EGR31558.1 - 0.06 12.6 0.1 0.15 11.3 0.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGR31558.1 - 0.066 12.4 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Ldh_1_N PF00056.23 EGR31558.1 - 0.08 13.0 0.1 0.45 10.6 0.1 2.1 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain ApbA PF02558.16 EGR31558.1 - 0.1 12.2 0.1 0.17 11.5 0.1 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 EGR31558.1 - 0.11 13.0 1.1 0.46 11.1 1.1 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RELT PF12606.8 EGR31558.1 - 0.27 10.3 2.3 0.58 9.2 2.3 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 EF-hand_7 PF13499.6 EGR31560.1 - 1.6e-12 47.7 23.4 3.1e-07 30.8 6.8 4.3 4 2 1 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.32 EGR31560.1 - 6.1e-12 44.2 19.8 1e-05 24.7 2.8 4.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGR31560.1 - 6.3e-09 35.1 26.2 0.0001 22.0 1.7 5.9 5 1 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 EGR31560.1 - 1.2e-08 34.6 11.6 0.0025 17.6 0.1 5.5 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 EGR31560.1 - 4.2e-05 22.9 9.3 0.043 13.3 1.4 3.8 3 0 0 3 3 3 2 EF hand Cdc6_C PF09079.11 EGR31560.1 - 0.094 12.7 0.9 1 9.4 0.1 2.5 2 0 0 2 2 2 0 CDC6, C terminal winged helix domain YqgF PF14639.6 EGR31560.1 - 8.2 6.2 17.8 0.11 12.3 6.6 3.1 2 1 1 3 3 3 0 Holliday-junction resolvase-like of SPT6 DUF3409 PF11889.8 EGR31561.1 - 0.081 12.8 0.3 0.15 11.9 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3409) HBS1_N PF08938.10 EGR31562.1 - 0.0045 17.3 1.1 0.0045 17.3 1.1 3.8 4 0 0 4 4 4 1 HBS1 N-terminus AKAP95 PF04988.12 EGR31562.1 - 0.019 15.2 0.8 0.019 15.2 0.8 4.0 1 1 3 4 4 4 0 A-kinase anchoring protein 95 (AKAP95) Polo_box_3 PF18544.1 EGR31562.1 - 3.8 8.2 11.7 0.97 10.1 1.8 3.3 1 1 2 3 3 3 0 Polo box domain MSC PF09402.10 EGR31562.1 - 9.6 5.5 14.6 0.89 8.9 0.2 2.2 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain TDA11 PF17084.5 EGR31563.1 - 0.022 13.7 0.5 0.029 13.3 0.5 1.1 1 0 0 1 1 1 0 Topoisomerase I damage affected protein 11 KH_10 PF17905.1 EGR31565.1 - 0.079 13.4 1.3 2.3 8.7 0.3 2.9 2 0 0 2 2 2 0 GLD-3 KH domain 5 KH_1 PF00013.29 EGR31566.1 - 8.4e-37 124.8 9.8 2.1e-12 46.7 0.6 3.3 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 EGR31566.1 - 1.2e-05 25.1 9.6 0.0015 18.3 0.2 3.5 2 1 2 4 4 4 2 KH domain KH_5 PF13184.6 EGR31566.1 - 0.0064 16.6 4.8 7.2 6.8 0.1 3.5 3 0 0 3 3 3 2 NusA-like KH domain vATP-synt_E PF01991.18 EGR31566.1 - 0.012 15.0 0.0 0.012 15.0 0.0 2.9 2 1 0 2 2 2 0 ATP synthase (E/31 kDa) subunit KH_4 PF13083.6 EGR31566.1 - 0.04 13.8 0.6 1.3 9.0 0.0 3.2 3 0 0 3 3 3 0 KH domain Pkinase PF00069.25 EGR31567.1 - 4e-79 265.7 0.0 4.5e-79 265.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31567.1 - 1.8e-33 115.9 0.0 2.2e-33 115.6 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR31567.1 - 1.8e-07 30.5 0.0 2.1e-06 27.0 0.0 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGR31567.1 - 2.8e-07 30.2 0.1 4e-05 23.1 0.0 2.3 2 1 0 2 2 2 2 Kinase-like APH PF01636.23 EGR31567.1 - 0.0012 18.9 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGR31567.1 - 0.0021 17.7 0.0 0.0033 17.0 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGR31567.1 - 0.0099 15.2 0.1 0.024 14.0 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ephrin_rec_like PF07699.13 EGR31568.1 - 6.5e-05 22.6 38.4 0.00053 19.7 2.5 7.1 2 1 5 7 7 7 6 Putative ephrin-receptor like Antistasin PF02822.14 EGR31568.1 - 0.00076 20.1 5.3 5.8 7.6 0.0 4.9 4 0 0 4 4 4 3 Antistasin family Ephrin_rec_like PF07699.13 EGR31569.1 - 0.0053 16.5 1.4 0.0053 16.5 1.4 7.9 1 1 7 8 8 8 4 Putative ephrin-receptor like Antistasin PF02822.14 EGR31569.1 - 0.022 15.4 9.9 9.7 6.9 0.0 5.8 6 0 0 6 6 6 0 Antistasin family Ephrin_rec_like PF07699.13 EGR31570.1 - 1.7e-08 34.0 49.8 0.0026 17.5 2.5 6.8 3 1 4 7 7 7 5 Putative ephrin-receptor like Antistasin PF02822.14 EGR31570.1 - 0.032 14.9 9.0 7.7 7.3 0.0 5.4 6 0 0 6 6 6 0 Antistasin family Ephrin_rec_like PF07699.13 EGR31571.1 - 0.034 13.9 0.8 0.034 13.9 0.8 3.6 4 1 0 4 4 4 0 Putative ephrin-receptor like Aldedh PF00171.22 EGR31572.1 - 3.8e-171 569.7 0.0 4.3e-171 569.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribosomal_S7e PF01251.18 EGR31574.1 - 3.4e-62 209.5 9.7 3.9e-62 209.3 9.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e TMEM132D_N PF15705.5 EGR31574.1 - 0.035 14.0 0.2 0.053 13.4 0.2 1.2 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, N-term Peptidase_C3 PF00548.20 EGR31574.1 - 0.076 12.9 0.3 0.14 12.1 0.1 1.6 1 1 0 1 1 1 0 3C cysteine protease (picornain 3C) DnaJ_C PF01556.18 EGR31575.1 - 4.8e-31 107.9 0.6 6.2e-31 107.5 0.6 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGR31575.1 - 2.3e-17 62.9 0.9 7.4e-17 61.2 0.9 1.9 1 0 0 1 1 1 1 DnaJ domain Ribosomal_L13e PF01294.18 EGR31576.1 - 0.027 14.3 3.0 0.028 14.3 0.9 1.9 1 1 1 2 2 2 0 Ribosomal protein L13e MCM PF00493.23 EGR31577.1 - 1.3e-97 325.3 1.1 2.5e-97 324.4 1.1 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 EGR31577.1 - 6.5e-28 97.0 2.1 2.9e-26 91.7 0.3 2.9 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_OB PF17207.3 EGR31577.1 - 3.7e-27 94.7 0.0 7e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_N PF14551.6 EGR31577.1 - 4.1e-17 62.7 1.1 4.1e-17 62.7 1.1 2.9 2 0 0 2 2 2 1 MCM N-terminal domain MCM2_N PF12619.8 EGR31577.1 - 3.5e-16 59.8 33.6 3.5e-16 59.8 33.6 1.9 2 0 0 2 2 2 1 Mini-chromosome maintenance protein 2 Mg_chelatase PF01078.21 EGR31577.1 - 3.8e-08 33.0 0.0 1e-06 28.3 0.0 2.6 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGR31577.1 - 2e-07 31.1 0.0 5.9e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGR31577.1 - 2.2e-06 27.5 0.0 1e-05 25.4 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGR31577.1 - 0.00051 19.8 0.1 0.0033 17.1 0.1 2.2 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 EGR31577.1 - 0.0052 17.2 2.7 0.05 14.0 0.0 3.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) IF-2B PF01008.17 EGR31578.1 - 1.8e-58 198.0 0.1 1.8e-58 198.0 0.1 1.6 2 0 0 2 2 2 1 Initiation factor 2 subunit family PP_kinase_C_1 PF17941.1 EGR31578.1 - 0.012 15.2 0.0 0.03 13.9 0.0 1.7 1 0 0 1 1 1 0 Polyphosphate kinase C-terminal domain 1 Avl9 PF09794.9 EGR31580.1 - 4.8e-78 262.5 18.3 5e-76 255.9 18.3 2.3 1 1 0 1 1 1 1 Transport protein Avl9 MORN PF02493.20 EGR31580.1 - 1.2e-20 72.1 44.1 0.0015 18.3 0.7 9.4 9 0 0 9 9 9 7 MORN repeat SPA PF08616.10 EGR31580.1 - 7.8e-10 38.7 6.0 1.5e-08 34.6 4.4 3.0 2 1 0 2 2 2 1 Stabilization of polarity axis Afi1 PF07792.12 EGR31580.1 - 1e-06 29.2 0.1 1e-06 29.2 0.1 3.4 3 1 0 3 3 3 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DENN PF02141.21 EGR31580.1 - 3e-05 24.1 0.9 0.0042 17.1 0.3 2.6 2 0 0 2 2 2 2 DENN (AEX-3) domain SWIRM PF04433.17 EGR31581.1 - 2.9e-31 107.7 2.4 8.7e-31 106.1 0.3 2.8 2 1 0 2 2 2 1 SWIRM domain Myb_DNA-binding PF00249.31 EGR31581.1 - 5.3e-10 39.3 0.1 1.1e-09 38.3 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGR31581.1 - 6.9e-08 32.6 1.5 3.1e-07 30.5 1.5 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGR31581.1 - 0.01 15.7 0.7 0.01 15.7 0.7 2.6 2 0 0 2 2 2 0 Myb DNA-binding like Lipase_GDSL PF00657.22 EGR31581.1 - 0.31 11.0 3.8 2.9 7.8 1.7 3.3 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase SANT_DAMP1_like PF16282.5 EGR31581.1 - 0.34 11.1 7.2 0.19 11.9 2.2 2.8 2 1 0 2 2 2 0 SANT/Myb-like domain of DAMP1 Actin PF00022.19 EGR31582.1 - 4.8e-78 262.6 0.5 6.4e-74 249.0 0.1 2.4 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 EGR31582.1 - 0.00097 18.0 0.0 0.0041 16.0 0.0 1.9 2 0 0 2 2 2 1 MreB/Mbl protein LMF1 PF06762.14 EGR31583.1 - 3.4e-39 135.2 6.5 4.7e-39 134.7 6.5 1.2 1 0 0 1 1 1 1 Lipase maturation factor Pkinase PF00069.25 EGR31583.1 - 5.2e-18 65.4 0.0 7.7e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31583.1 - 4.3e-09 36.0 0.0 6e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EGR31585.1 - 9.7e-17 61.2 0.1 1.2e-16 60.9 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGR31585.1 - 5.1e-14 51.0 1.0 1.3e-06 27.6 0.3 2.3 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 EGR31585.1 - 6.1e-14 50.4 1.0 3.8e-06 26.1 0.3 2.4 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGR31585.1 - 5.5e-12 45.3 0.8 1.7e-07 31.0 0.2 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR31585.1 - 1.1e-11 43.7 0.1 0.00022 20.9 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EGR31585.1 - 0.002 18.4 0.2 0.014 15.7 0.1 1.9 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 EGR31585.1 - 0.0027 17.8 0.2 0.18 12.0 0.2 2.1 1 1 0 1 1 1 1 Dockerin type I domain EF-hand_4 PF12763.7 EGR31585.1 - 0.016 15.2 0.7 0.86 9.6 0.1 2.0 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Fer4_24 PF18109.1 EGR31585.1 - 0.034 14.4 2.7 0.1 12.9 0.6 2.2 2 0 0 2 2 2 0 Ferredoxin I 4Fe-4S cluster domain EF-hand_10 PF14788.6 EGR31585.1 - 0.047 13.6 0.1 2 8.3 0.0 2.4 2 0 0 2 2 2 0 EF hand EF-hand_9 PF14658.6 EGR31585.1 - 0.058 13.7 0.0 0.083 13.2 0.0 1.3 1 0 0 1 1 1 0 EF-hand domain Phage_TAC_12 PF12363.8 EGR31585.1 - 0.066 13.6 2.7 0.094 13.1 0.6 2.1 1 1 1 2 2 2 0 Phage tail assembly chaperone protein, TAC GIT_SHD PF08518.11 EGR31585.1 - 0.11 12.2 0.3 7.3 6.3 0.0 2.3 2 0 0 2 2 2 0 Spa2 homology domain (SHD) of GIT JmjC PF02373.22 EGR31586.1 - 1.6e-35 122.0 0.6 1.6e-35 122.0 0.6 2.2 2 0 0 2 2 2 1 JmjC domain, hydroxylase JmjN PF02375.17 EGR31586.1 - 1.8e-11 43.8 2.4 4.8e-11 42.4 2.4 1.8 1 0 0 1 1 1 1 jmjN domain Phosphoesterase PF04185.14 EGR31587.1 - 1.9e-79 267.5 5.1 1.9e-79 267.5 5.1 2.4 2 1 1 3 3 3 1 Phosphoesterase family SAM_KSR1 PF13543.6 EGR31587.1 - 0.029 14.5 2.7 0.058 13.5 0.9 2.3 2 0 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 CENP-F_leu_zip PF10473.9 EGR31587.1 - 0.059 13.4 16.3 1.3 9.1 5.5 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4164 PF13747.6 EGR31587.1 - 0.11 12.7 7.1 0.13 12.6 5.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) NRBF2 PF08961.10 EGR31587.1 - 0.28 10.8 8.2 0.065 12.8 4.3 1.9 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator SurA_N_3 PF13624.6 EGR31587.1 - 0.96 9.2 7.5 16 5.2 0.1 2.7 2 0 0 2 2 2 0 SurA N-terminal domain Sas6_CC PF18594.1 EGR31587.1 - 1.2 9.0 4.3 13 5.6 0.2 3.5 2 1 1 3 3 3 0 Sas6/XLF/XRCC4 coiled-coil domain FAM76 PF16046.5 EGR31587.1 - 1.5 8.1 17.2 3.3 7.0 17.2 1.6 1 0 0 1 1 1 0 FAM76 protein HALZ PF02183.18 EGR31587.1 - 2 8.7 6.2 3.3 8.0 0.2 3.3 2 1 1 3 3 3 0 Homeobox associated leucine zipper APG6_N PF17675.1 EGR31587.1 - 2.7 8.5 16.8 0.39 11.3 12.3 1.9 1 1 0 2 2 2 0 Apg6 coiled-coil region bZIP_2 PF07716.15 EGR31587.1 - 3.3 7.8 8.7 0.47 10.6 1.0 3.0 2 1 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 EGR31587.1 - 3.9 7.3 10.5 2 8.3 3.2 3.2 2 1 1 3 3 3 0 Septum formation initiator Cse1 PF08506.10 EGR31588.1 - 8.7e-05 21.5 1.0 0.00017 20.5 0.1 1.8 2 0 0 2 2 2 1 Cse1 SHIPPO-rpt PF07004.12 EGR31590.1 - 0.014 16.3 1.3 4.2 8.4 0.1 2.6 2 0 0 2 2 2 0 Sperm-tail PG-rich repeat Myc-LZ PF02344.15 EGR31591.1 - 0.018 15.1 3.2 0.018 15.1 3.2 3.8 4 0 0 4 4 4 0 Myc leucine zipper domain TSC22 PF01166.18 EGR31591.1 - 0.032 14.5 1.2 0.032 14.5 1.2 5.2 4 1 1 5 5 5 0 TSC-22/dip/bun family Alkyl_sulf_dimr PF14863.6 EGR31591.1 - 0.067 13.7 0.2 0.24 11.8 0.2 1.9 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation YabA PF06156.13 EGR31591.1 - 0.7 10.6 34.7 0.52 11.0 6.8 4.1 3 2 0 3 3 3 0 Initiation control protein YabA APG6_N PF17675.1 EGR31591.1 - 5 7.7 42.2 3.4 8.2 1.0 3.8 2 1 2 4 4 4 0 Apg6 coiled-coil region Ax_dynein_light PF10211.9 EGR31591.1 - 5 7.0 36.6 2.1 8.3 7.3 3.5 3 0 0 3 3 3 0 Axonemal dynein light chain DASH_Dad4 PF08650.10 EGR31591.1 - 8.5 6.4 27.9 0.06 13.3 1.2 4.6 4 1 0 4 4 4 0 DASH complex subunit Dad4 Acyltransferase PF01553.21 EGR31592.1 - 1.5e-05 24.6 0.0 0.0001 22.0 0.0 2.2 1 1 0 1 1 1 1 Acyltransferase FlhC PF05280.11 EGR31592.1 - 0.18 11.5 1.4 3.1 7.5 0.4 2.2 1 1 1 2 2 2 0 Flagellar transcriptional activator (FlhC) PAP2 PF01569.21 EGR31593.1 - 5.1e-16 58.7 1.0 5.1e-16 58.7 1.0 2.8 2 1 0 2 2 2 1 PAP2 superfamily PIRT PF15099.6 EGR31593.1 - 3.9 7.1 6.4 9.1 5.9 0.4 2.9 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family ALMT PF11744.8 EGR31593.1 - 5.3 5.8 9.5 0.5 9.1 4.9 1.6 2 0 0 2 2 2 0 Aluminium activated malate transporter Col_cuticle_N PF01484.17 EGR31593.1 - 8.4 6.5 9.4 7.6 6.7 2.5 3.1 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Kinesin PF00225.23 EGR31594.1 - 1.6e-107 359.3 6.2 2e-107 359.0 6.2 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR31594.1 - 1.3e-30 106.3 0.3 1.3e-30 106.3 0.3 1.8 2 0 0 2 2 2 1 Microtubule binding Pkinase PF00069.25 EGR31595.1 - 3.7e-63 213.4 3.3 4.2e-63 213.2 3.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31595.1 - 4.7e-42 144.1 0.2 6e-42 143.7 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31595.1 - 5.7e-05 22.6 0.2 0.00025 20.5 0.2 1.9 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 EGR31595.1 - 0.00057 19.5 0.2 0.0011 18.5 0.2 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 EGR31595.1 - 0.0046 16.3 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGR31595.1 - 0.0047 16.5 1.1 0.028 14.0 0.0 2.2 2 0 0 2 2 2 1 RIO1 family MORN PF02493.20 EGR31596.1 - 1.2e-53 175.9 71.6 7e-08 31.9 1.7 10.4 10 0 0 10 10 10 9 MORN repeat Suf PF05843.14 EGR31596.1 - 0.51 10.3 10.2 0.78 9.7 10.2 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1741 PF08427.10 EGR31596.1 - 1.6 8.4 7.0 6.7 6.3 7.0 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1741) Tudor_2 PF18104.1 EGR31596.1 - 1.6 8.5 24.3 0.72 9.6 0.3 6.8 6 0 0 6 6 6 0 Jumonji domain-containing protein 2A Tudor domain MTS PF05175.14 EGR31597.1 - 7.6e-08 32.1 1.3 0.021 14.4 0.0 3.1 2 1 1 3 3 3 2 Methyltransferase small domain Methyltransf_31 PF13847.6 EGR31597.1 - 5.2e-06 26.3 1.4 0.0011 18.8 1.4 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGR31597.1 - 0.0026 17.6 0.0 0.0048 16.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Eco57I PF07669.11 EGR31597.1 - 0.011 16.3 0.4 0.023 15.2 0.4 1.8 1 1 0 1 1 1 0 Eco57I restriction-modification methylase Methyltransf_25 PF13649.6 EGR31597.1 - 0.017 15.8 0.3 0.083 13.6 0.3 2.3 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGR31597.1 - 0.02 15.6 0.1 0.044 14.5 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 EGR31597.1 - 0.023 14.1 0.0 6.2 6.3 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_11 PF08241.12 EGR31597.1 - 0.041 14.5 0.0 0.065 13.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EGR31597.1 - 0.045 13.1 0.1 0.095 12.1 0.0 1.5 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MetW PF07021.12 EGR31597.1 - 0.048 13.2 0.1 0.18 11.4 0.0 1.8 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 EGR31597.1 - 0.049 13.6 0.5 8 6.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.15 EGR31597.1 - 0.079 12.6 0.8 8.3 6.0 0.2 2.8 1 1 2 3 3 3 0 Conserved hypothetical protein 95 Pkinase PF00069.25 EGR31598.1 - 8.8e-23 81.0 0.9 8.8e-23 81.0 0.9 1.9 2 0 0 2 2 2 1 Protein kinase domain FHA PF00498.26 EGR31598.1 - 2.8e-22 78.8 5.2 3e-13 49.9 0.0 3.8 4 0 0 4 4 4 2 FHA domain Yop-YscD_cpl PF16697.5 EGR31598.1 - 5.4e-17 61.9 0.0 1.5e-07 31.6 0.0 3.0 3 0 0 3 3 3 2 Inner membrane component of T3SS, cytoplasmic domain Pkinase_Tyr PF07714.17 EGR31598.1 - 1.2e-14 54.2 0.1 2.8e-14 53.0 0.1 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase zf-C3HC4_3 PF13920.6 EGR31598.1 - 4.5e-12 45.6 10.8 8.8e-12 44.7 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Pkinase_fungal PF17667.1 EGR31598.1 - 4e-11 42.3 0.0 1e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Prok-RING_4 PF14447.6 EGR31598.1 - 1.2e-06 28.2 10.2 2.3e-06 27.3 10.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 SAM_2 PF07647.17 EGR31598.1 - 0.0016 18.5 0.1 0.0061 16.6 0.1 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) MU2_FHA PF18221.1 EGR31598.1 - 0.0018 18.3 0.0 2.9 8.0 0.0 2.7 2 0 0 2 2 2 2 Mutator 2 Fork head associated domain zf-RING_5 PF14634.6 EGR31598.1 - 0.0027 17.6 8.8 0.0063 16.5 8.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain APH PF01636.23 EGR31598.1 - 0.0064 16.4 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family zf-RING_2 PF13639.6 EGR31598.1 - 0.01 16.2 10.9 0.023 15.0 10.9 1.6 1 0 0 1 1 1 0 Ring finger domain Kdo PF06293.14 EGR31598.1 - 0.046 13.1 0.0 0.099 12.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_4 PF12799.7 EGR31599.1 - 4.5e-10 39.6 10.6 3.3e-05 24.1 1.2 3.9 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGR31599.1 - 1.8e-08 34.1 2.1 1.8e-08 34.1 2.1 2.1 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 EGR31599.1 - 1.3e-05 24.9 8.5 1.9e-05 24.3 3.5 3.4 3 1 1 4 4 4 1 Leucine rich repeat LRR_6 PF13516.6 EGR31599.1 - 0.0072 16.3 0.2 22 5.4 0.1 4.3 4 0 0 4 4 4 0 Leucine Rich repeat DDHD PF02862.17 EGR31599.1 - 0.13 12.4 8.8 1.9 8.6 1.0 2.2 2 0 0 2 2 2 0 DDHD domain LRR_1 PF00560.33 EGR31599.1 - 0.14 12.8 3.6 3.1e+02 2.6 2.4 4.8 3 2 0 3 3 3 0 Leucine Rich Repeat NPL PF17800.1 EGR31599.1 - 4.4 7.9 6.2 11 6.6 0.3 2.5 2 0 0 2 2 2 0 Nucleoplasmin-like domain DUF4666 PF15697.5 EGR31599.1 - 5.2 7.8 10.8 12 6.6 2.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) LAGLIDADG_WhiA PF14527.6 EGR31600.1 - 1.2 9.3 6.5 7.3 6.7 0.2 2.6 2 1 0 3 3 3 0 WhiA LAGLIDADG-like domain UTP15_C PF09384.10 EGR31601.1 - 0.053 13.2 0.1 0.84 9.3 0.0 2.5 1 1 0 2 2 2 0 UTP15 C terminal Sda PF08970.10 EGR31601.1 - 0.18 11.6 0.1 0.18 11.6 0.1 3.2 5 0 0 5 5 5 0 Sporulation inhibitor A PHD PF00628.29 EGR31602.1 - 2e-07 30.8 14.3 4.1e-07 29.8 14.3 1.5 1 0 0 1 1 1 1 PHD-finger C1_2 PF03107.16 EGR31602.1 - 0.0038 17.5 11.0 0.029 14.7 5.9 2.6 2 0 0 2 2 2 1 C1 domain C1_1 PF00130.22 EGR31602.1 - 0.0079 16.1 10.4 0.0079 16.1 10.4 2.3 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 EGR31602.1 - 0.022 14.3 6.7 0.022 14.3 6.7 2.1 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 EGR31602.1 - 0.051 13.5 11.0 0.23 11.4 10.9 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Thioredoxin_3 PF13192.6 EGR31602.1 - 0.12 12.5 0.4 0.12 12.5 0.4 2.5 2 1 1 3 3 2 0 Thioredoxin domain zf-HC5HC2H PF13771.6 EGR31602.1 - 0.31 11.3 18.6 3.6 7.9 18.6 2.4 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_2 PF13639.6 EGR31602.1 - 0.86 10.0 10.8 1.7 9.1 10.8 1.5 1 0 0 1 1 1 0 Ring finger domain PHD_4 PF16866.5 EGR31602.1 - 0.86 9.7 12.5 1.9 8.6 10.5 2.4 1 1 1 2 2 2 0 PHD-finger zf-rbx1 PF12678.7 EGR31602.1 - 1 9.7 12.5 1.9 8.8 11.9 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain Zf_RING PF16744.5 EGR31602.1 - 1.7 8.8 10.4 2.5 8.3 9.1 2.0 1 1 0 1 1 1 0 KIAA1045 RING finger zf-C4pol PF14260.6 EGR31602.1 - 4.9 7.7 20.4 3.2e+02 1.9 19.4 2.6 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta PolC_DP2 PF03833.13 EGR31602.1 - 5.1 4.8 12.3 7.4 4.3 12.3 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Prok-RING_2 PF14445.6 EGR31602.1 - 6.7 7.0 7.6 36 4.6 7.6 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 2 Ribonuc_L-PSP PF01042.21 EGR31603.1 - 6.9e-25 87.4 0.1 7.3e-25 87.3 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP Peptidase_M16 PF00675.20 EGR31604.1 - 3.5e-27 95.2 0.6 7.4e-27 94.2 0.6 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGR31604.1 - 3e-12 46.9 1.7 5.7e-12 46.0 0.9 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Erp_C PF06780.11 EGR31604.1 - 0.024 14.6 0.2 0.31 11.0 0.0 2.2 2 0 0 2 2 2 0 Erp protein C-terminus Prok-E2_D PF14460.6 EGR31604.1 - 0.081 12.6 0.2 0.18 11.5 0.2 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family D WD40 PF00400.32 EGR31605.1 - 2e-42 142.4 11.9 1.7e-07 31.8 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR31605.1 - 1.1e-19 70.5 0.2 9.1e-05 22.7 0.0 6.2 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGR31605.1 - 9.8e-08 31.7 5.3 0.0061 15.9 0.1 4.2 4 1 0 4 4 4 2 WD40-like domain Ge1_WD40 PF16529.5 EGR31605.1 - 3.9e-05 22.8 2.5 0.031 13.2 0.2 4.5 1 1 4 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGR31605.1 - 0.00037 19.3 2.3 0.011 14.5 0.7 2.8 1 1 2 3 3 3 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EGR31605.1 - 0.0035 15.9 0.2 0.096 11.2 0.0 2.7 2 1 1 3 3 3 2 Cytochrome D1 heme domain Transket_pyr PF02779.24 EGR31606.1 - 3.2e-52 176.8 0.0 4.9e-52 176.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EGR31606.1 - 3.6e-52 177.2 0.0 6.3e-52 176.4 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EGR31606.1 - 2.1e-31 108.6 0.2 5.4e-31 107.3 0.2 1.7 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal YhfZ_C PF14503.6 EGR31606.1 - 0.017 14.6 0.0 0.11 12.0 0.0 2.1 2 0 0 2 2 2 0 YhfZ C-terminal domain Ion_trans PF00520.31 EGR31607.1 - 8.1e-191 631.1 143.6 1.6e-50 171.7 14.4 5.2 5 0 0 5 5 5 4 Ion transport protein PKD_channel PF08016.12 EGR31607.1 - 3.8e-13 48.9 118.5 4.9e-06 25.5 28.7 10.0 7 3 2 9 9 9 7 Polycystin cation channel EF-hand_1 PF00036.32 EGR31608.1 - 1.8e-36 121.0 42.1 9.6e-07 27.9 0.5 9.7 10 0 0 10 10 10 8 EF hand EF-hand_6 PF13405.6 EGR31608.1 - 8.7e-36 118.8 34.6 5.4e-06 25.9 0.3 9.5 9 0 0 9 9 9 7 EF-hand domain EF-hand_7 PF13499.6 EGR31608.1 - 9.5e-30 102.9 32.7 1.8e-10 41.1 0.7 7.0 4 2 3 7 7 7 7 EF-hand domain pair EF-hand_8 PF13833.6 EGR31608.1 - 9.9e-23 79.8 30.4 1.8e-08 34.1 2.0 7.9 7 1 1 8 8 8 4 EF-hand domain pair EF-hand_5 PF13202.6 EGR31608.1 - 1.2e-20 72.0 30.8 0.00012 21.4 0.4 8.4 8 0 0 8 8 8 6 EF hand EF-hand_4 PF12763.7 EGR31608.1 - 6.5e-06 26.1 9.4 0.064 13.2 0.3 5.1 2 2 3 5 5 5 2 Cytoskeletal-regulatory complex EF hand Flagellin_D3 PF08884.11 EGR31608.1 - 0.023 15.1 0.5 0.23 11.8 0.1 2.4 2 0 0 2 2 2 0 Flagellin D3 domain EF-hand_11 PF08976.11 EGR31608.1 - 0.096 13.6 3.1 5.9 7.8 0.1 4.1 4 0 0 4 4 4 0 EF-hand domain Fer4_18 PF13746.6 EGR31608.1 - 0.1 12.8 0.8 0.32 11.2 0.8 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain EF-hand_13 PF17958.1 EGR31608.1 - 0.22 11.3 2.0 19 5.1 0.1 3.9 4 0 0 4 4 4 0 EF-hand domain PilN_bio_d PF18222.1 EGR31608.1 - 0.22 11.9 0.1 0.22 11.9 0.1 3.0 3 0 0 3 3 3 0 PilN biogenesis protein dimerization domain EF-hand_10 PF14788.6 EGR31608.1 - 1.1 9.2 9.2 1.3 8.9 0.2 4.6 6 0 0 6 6 6 0 EF hand Dockerin_1 PF00404.18 EGR31608.1 - 2 8.6 6.6 13 6.0 0.0 4.2 4 1 0 4 4 4 0 Dockerin type I domain Pkinase PF00069.25 EGR31609.1 - 2.3e-26 92.8 0.9 2.7e-26 92.5 0.9 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31609.1 - 5.4e-15 55.4 0.0 6.5e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR31609.1 - 2.5e-07 29.8 0.3 3.1e-07 29.5 0.3 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR31609.1 - 0.0093 15.3 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR31609.1 - 0.19 11.6 0.0 0.48 10.3 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF2428 PF10350.9 EGR31610.1 - 1.3e-49 168.9 2.0 4.6e-49 167.1 2.0 2.0 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) GM_CSF PF01109.17 EGR31610.1 - 0.047 13.8 1.2 0.19 11.9 0.3 2.5 2 0 0 2 2 2 0 Granulocyte-macrophage colony-stimulating factor MFS_1 PF07690.16 EGR31611.1 - 1.4e-20 73.5 9.8 1.4e-20 73.5 9.8 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGR31611.1 - 1.6e-10 40.5 21.8 3.3e-09 36.1 21.8 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter DUF4079 PF13301.6 EGR31611.1 - 0.78 9.9 4.0 3.7 7.7 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4079) Phage_holin_3_2 PF04550.12 EGR31611.1 - 4.9 7.8 5.6 1.2 9.7 0.9 2.3 2 1 1 3 3 3 0 Phage holin family 2 Pkinase PF00069.25 EGR31612.1 - 1.4e-33 116.4 9.8 1.9e-33 116.0 9.8 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31612.1 - 2.2e-18 66.5 1.4 2.3e-18 66.4 0.6 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR31612.1 - 0.00044 19.7 0.7 0.00075 18.9 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGR31612.1 - 0.00046 19.6 0.5 0.0013 18.1 0.0 1.7 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EGR31612.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family MYO10_CC PF16735.5 EGR31613.1 - 0.032 14.3 5.1 0.13 12.4 5.1 2.2 1 0 0 1 1 1 0 Unconventional myosin-X coiled coil domain Syntaxin-6_N PF09177.11 EGR31613.1 - 0.091 13.3 4.0 0.28 11.8 0.2 2.6 2 1 0 2 2 2 0 Syntaxin 6, N-terminal Peptidase_M19 PF01244.21 EGR31613.1 - 0.093 11.9 2.0 0.13 11.4 2.0 1.3 1 0 0 1 1 1 0 Membrane dipeptidase (Peptidase family M19) OMPdecase PF00215.24 EGR31613.1 - 0.096 12.3 0.2 1.3 8.5 0.1 2.1 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family PCRF PF03462.18 EGR31613.1 - 2 8.2 9.2 2 8.2 0.4 2.2 2 0 0 2 2 2 0 PCRF domain zf-B_box PF00643.24 EGR31613.1 - 3.9 7.7 7.9 7.1 6.9 7.9 1.4 1 0 0 1 1 1 0 B-box zinc finger DUF730 PF05325.11 EGR31613.1 - 5.3 7.1 7.0 1.3 9.0 2.3 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF730) Furin-like_2 PF15913.5 EGR31614.1 - 1.8e-31 108.5 409.9 4.8e-08 33.1 15.0 20.0 1 1 21 22 22 22 16 Furin-like repeat, cysteine-rich GF_recep_IV PF14843.6 EGR31614.1 - 1.1e-24 86.7 427.4 2e-10 40.6 32.3 15.3 1 1 18 19 19 19 11 Growth factor receptor domain IV VSP PF03302.13 EGR31614.1 - 0.2 10.5 388.4 0.29 10.0 39.1 19.1 1 1 15 17 17 17 0 Giardia variant-specific surface protein TMEM144 PF07857.12 EGR31615.1 - 0.35 9.8 4.3 0.4 9.6 4.3 1.1 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters JHY PF15261.6 EGR31615.1 - 3.1 8.5 10.1 5.8 7.6 10.1 1.5 1 1 0 1 1 1 0 Jhy protein DSPc PF00782.20 EGR31616.1 - 2.7e-31 108.1 1.7 7.8e-31 106.6 1.7 1.6 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EGR31616.1 - 2.5e-05 24.5 0.0 3.6e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 EGR31616.1 - 4.7e-05 23.6 0.0 5.7e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EGR31616.1 - 0.0029 17.2 0.0 0.0034 17.0 0.0 1.4 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EGR31616.1 - 0.0033 17.0 0.1 0.0049 16.5 0.1 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EGR31616.1 - 0.0041 17.1 0.0 0.0067 16.4 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family RRM_1 PF00076.22 EGR31617.1 - 1.8e-06 27.7 3.3 3.5e-05 23.5 0.5 2.0 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 EGR31617.1 - 4.8e-05 23.2 1.2 7.4e-05 22.7 1.2 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 EGR31617.1 - 0.018 14.7 1.5 0.049 13.3 1.0 1.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 EGR31617.1 - 0.057 13.4 0.4 0.18 11.8 0.1 1.9 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 EGR31617.1 - 0.12 12.1 0.2 0.23 11.2 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Ank_4 PF13637.6 EGR31618.1 - 5.1e-36 122.6 12.8 8.3e-10 39.0 0.2 5.7 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGR31618.1 - 1.4e-30 105.7 14.2 4.6e-13 49.6 0.6 4.7 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGR31618.1 - 3.4e-29 100.5 9.1 4.4e-10 39.6 0.1 5.1 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EGR31618.1 - 1.3e-26 91.8 8.0 0.00017 21.9 0.0 7.3 7 0 0 7 7 7 7 Ankyrin repeat Ank_3 PF13606.6 EGR31618.1 - 9.7e-25 84.0 8.3 0.00058 20.1 0.1 7.5 7 0 0 7 7 7 5 Ankyrin repeat Peptidase_C2 PF00648.21 EGR31619.1 - 4.4e-73 245.9 0.1 8.3e-73 245.0 0.1 1.5 1 0 0 1 1 1 1 Calpain family cysteine protease cNMP_binding PF00027.29 EGR31619.1 - 0.0017 18.3 0.0 2.9 8.0 0.0 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Swi3 PF07962.12 EGR31619.1 - 0.0063 16.5 0.1 0.025 14.6 0.1 2.1 2 0 0 2 2 2 1 Replication Fork Protection Component Swi3 Lipase_GDSL_2 PF13472.6 EGR31619.1 - 0.022 15.2 0.0 0.046 14.1 0.0 1.5 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Pro_isomerase PF00160.21 EGR31620.1 - 3.8e-42 144.2 0.3 4.2e-42 144.1 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Response_reg PF00072.24 EGR31621.1 - 1.3e-07 31.8 0.0 0.0055 16.9 0.0 2.6 1 1 1 2 2 2 2 Response regulator receiver domain DUF2448 PF10476.9 EGR31621.1 - 0.0038 17.1 0.1 0.0066 16.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2448) UK PF02512.14 EGR31621.1 - 0.073 13.6 0.0 4 8.0 0.0 2.3 2 0 0 2 2 2 0 Virulence determinant Peptidase_M16_M PF16187.5 EGR31622.1 - 7.5e-61 205.9 16.1 7.5e-61 205.9 16.1 3.1 3 0 0 3 3 3 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EGR31622.1 - 2.9e-37 127.9 2.2 6.2e-37 126.9 0.1 2.7 3 0 0 3 3 3 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGR31622.1 - 1.4e-24 87.1 5.3 1.5e-17 64.2 0.1 3.0 3 0 0 3 3 3 2 Peptidase M16 inactive domain ADSL_C PF10397.9 EGR31622.1 - 0.11 13.0 0.0 0.26 11.8 0.0 1.6 1 0 0 1 1 1 0 Adenylosuccinate lyase C-terminus Radial_spoke PF04712.12 EGR31624.1 - 3.2e-68 230.9 11.6 2.9e-39 135.4 1.7 2.4 1 1 1 2 2 2 2 Radial spokehead-like protein E3_UbLigase_R4 PF13764.6 EGR31624.1 - 0.17 10.0 1.3 0.22 9.6 1.3 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase UBR4 ICL PF00463.21 EGR31625.1 - 1.1e-178 595.0 0.4 8.5e-118 394.1 0.0 2.0 1 1 1 2 2 2 2 Isocitrate lyase family PEP_mutase PF13714.6 EGR31625.1 - 3.2e-12 46.4 0.0 5.3e-12 45.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase IZUMO PF15005.6 EGR31625.1 - 0.24 11.9 2.1 0.68 10.4 0.5 2.4 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated DUF1192 PF06698.11 EGR31626.1 - 0.39 10.8 13.8 0.33 11.0 1.5 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Peptidase_M20 PF01546.28 EGR31627.1 - 2.2e-29 102.7 0.0 2.8e-29 102.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGR31627.1 - 2.9e-05 23.9 0.0 6.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGR31627.1 - 0.19 11.4 0.0 0.81 9.3 0.0 1.8 2 0 0 2 2 2 0 Peptidase family M28 Guanylate_cyc PF00211.20 EGR31628.1 - 2.3e-48 164.3 2.5 2.7e-48 164.0 2.5 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Phage_sheath_1C PF17482.2 EGR31628.1 - 0.0016 18.4 0.3 0.015 15.3 0.1 2.3 2 0 0 2 2 2 1 Phage tail sheath C-terminal domain Guanylate_cyc PF00211.20 EGR31629.1 - 2.8e-18 66.2 0.4 3.2e-18 66.0 0.4 1.0 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain zf-C2H2_jaz PF12171.8 EGR31630.1 - 3.7e-09 36.6 2.8 1.3e-08 34.9 2.8 2.1 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGR31630.1 - 4.4e-06 26.9 2.5 9.3e-06 25.9 2.5 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.26 EGR31630.1 - 0.079 13.4 0.3 0.079 13.4 0.3 2.1 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGR31630.1 - 4.1 8.5 5.0 0.68 10.9 0.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger RdRP PF05183.12 EGR31631.1 - 1.5e-96 324.4 3.3 2.1e-96 323.9 3.3 1.2 1 0 0 1 1 1 1 RNA dependent RNA polymerase Scramblase PF03803.15 EGR31632.1 - 2e-21 76.3 2.0 8e-20 71.1 2.0 2.2 1 1 0 1 1 1 1 Scramblase DUF2733 PF10813.8 EGR31632.1 - 0.7 9.7 7.6 1.5 8.7 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2733) SHIPPO-rpt PF07004.12 EGR31633.1 - 0.00011 23.0 20.4 0.033 15.1 2.1 4.5 3 1 1 4 4 4 3 Sperm-tail PG-rich repeat Ank_4 PF13637.6 EGR31634.1 - 4.7e-12 46.2 7.1 0.0072 16.9 0.1 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGR31634.1 - 5e-12 46.2 3.6 1.1e-05 25.9 1.3 4.1 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank PF00023.30 EGR31634.1 - 3.3e-11 43.1 1.4 0.03 14.8 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EGR31634.1 - 1.8e-09 37.0 5.9 0.5 11.1 0.0 5.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EGR31634.1 - 2.4e-08 34.1 0.6 0.0027 18.0 0.0 4.3 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Anoctamin PF04547.12 EGR31635.1 - 9.9e-42 143.3 26.4 2.2e-41 142.2 26.4 1.6 1 0 0 1 1 1 1 Calcium-activated chloride channel zf-B_box PF00643.24 EGR31635.1 - 6e-05 23.1 5.4 6e-05 23.1 5.4 1.8 2 0 0 2 2 2 1 B-box zinc finger zf-RING_6 PF14835.6 EGR31635.1 - 0.014 15.3 0.9 0.046 13.6 0.9 1.9 1 0 0 1 1 1 0 zf-RING of BARD1-type protein CEBP_ZZ PF16366.5 EGR31635.1 - 0.021 15.0 4.6 0.049 13.9 4.6 1.5 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain IBR PF01485.21 EGR31635.1 - 0.73 10.1 5.9 3.1 8.1 5.9 2.2 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Na_H_Exchanger PF00999.21 EGR31636.1 - 3.5e-48 164.3 38.9 6.5e-48 163.4 38.9 1.4 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family cNMP_binding PF00027.29 EGR31636.1 - 2.6e-05 24.2 0.0 7.8e-05 22.7 0.0 1.9 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain rhaM PF05336.13 EGR31637.1 - 0.28 11.3 3.4 1.3 9.2 0.1 2.6 2 1 0 2 2 2 0 L-rhamnose mutarotase DUF4580 PF15162.6 EGR31638.1 - 0.00017 21.2 1.0 0.0003 20.4 1.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4580) Phage_int_SAM_5 PF13102.6 EGR31638.1 - 0.34 11.3 9.8 3.6 8.0 4.5 2.6 2 1 0 2 2 2 0 Phage integrase SAM-like domain Acetyltransf_1 PF00583.25 EGR31639.1 - 3.7e-17 62.6 0.0 4.8e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGR31639.1 - 2.1e-10 40.9 0.3 4.2e-10 39.9 0.2 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGR31639.1 - 3.2e-08 33.6 0.1 4.2e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGR31639.1 - 7e-05 23.0 0.5 8.5e-05 22.7 0.5 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGR31639.1 - 0.00013 21.8 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EGR31639.1 - 0.0038 17.3 0.0 0.008 16.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGR31639.1 - 0.0054 17.4 0.0 0.0059 17.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGR31639.1 - 0.011 15.4 0.0 0.017 14.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGR31639.1 - 0.079 13.1 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase RNA_pol_A_bac PF01000.26 EGR31641.1 - 3.5e-30 104.7 1.2 1.4e-28 99.5 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EGR31641.1 - 3.7e-20 71.1 0.0 1.2e-19 69.5 0.0 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Laminin_EGF PF00053.24 EGR31641.1 - 0.0024 18.0 2.0 0.0024 18.0 2.0 2.1 2 0 0 2 2 2 1 Laminin EGF domain ETF_QO PF05187.13 EGR31641.1 - 0.019 15.1 5.2 0.021 15.0 3.1 2.1 2 1 1 3 3 3 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_10 PF13237.6 EGR31641.1 - 0.89 9.7 10.7 0.14 12.3 5.5 2.3 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGR31641.1 - 1.2 9.4 11.9 0.36 11.0 5.5 2.5 2 0 0 2 2 2 0 4Fe-4S dicluster domain Na_Ca_ex PF01699.24 EGR31643.1 - 4.9e-18 65.5 10.5 5.5e-18 65.4 10.5 1.0 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF5310 PF17237.2 EGR31643.1 - 0.059 13.3 1.5 0.059 13.3 1.5 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5310) PHP PF02811.19 EGR31643.1 - 0.11 12.8 0.0 0.12 12.7 0.0 1.2 1 0 0 1 1 1 0 PHP domain DUF3482 PF11981.8 EGR31644.1 - 0.22 10.9 0.7 0.28 10.6 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3482) ANAPC4_WD40 PF12894.7 EGR31645.1 - 9.2e-07 29.1 0.2 0.046 14.0 0.0 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGR31645.1 - 0.00041 21.1 0.0 0.12 13.2 0.0 3.2 3 0 0 3 3 3 1 WD domain, G-beta repeat Mak10 PF04112.13 EGR31646.1 - 3.7e-16 59.1 0.1 9e-16 57.8 0.1 1.6 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase zf-DNL PF05180.12 EGR31647.1 - 7e-30 102.8 0.9 7.9e-30 102.6 0.9 1.0 1 0 0 1 1 1 1 DNL zinc finger Jiv90 PF14901.6 EGR31647.1 - 0.026 14.7 0.2 0.032 14.4 0.2 1.1 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone zf-LSD1 PF06943.12 EGR31647.1 - 0.3 11.0 2.6 1.8 8.5 0.0 2.2 2 0 0 2 2 2 0 LSD1 zinc finger zinc_ribbon_4 PF13717.6 EGR31647.1 - 1.1 9.2 5.8 15 5.6 0.0 2.5 3 0 0 3 3 3 0 zinc-ribbon domain Ras PF00071.22 EGR31649.1 - 2e-42 144.5 0.4 3.1e-42 143.9 0.4 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR31649.1 - 4.2e-13 49.6 0.1 1.3e-12 47.9 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EGR31649.1 - 4.2e-07 29.7 0.0 5.6e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGR31649.1 - 4.9e-06 26.6 0.1 0.0056 16.6 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase Arf PF00025.21 EGR31649.1 - 0.00031 20.2 0.7 0.00049 19.6 0.1 1.6 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR31649.1 - 0.00063 19.8 0.0 0.0013 18.7 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EGR31649.1 - 0.015 15.3 1.3 0.08 13.0 0.1 2.5 1 1 2 3 3 3 0 C-terminal region of MMR_HSR1 domain FeoB_N PF02421.18 EGR31649.1 - 0.016 14.7 0.0 0.028 13.9 0.0 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B Furin-like_2 PF15913.5 EGR31650.1 - 0.00027 21.0 14.9 0.00027 21.0 14.9 2.1 1 1 1 2 2 2 1 Furin-like repeat, cysteine-rich Fer4_3 PF12798.7 EGR31650.1 - 0.054 14.5 1.5 0.054 14.5 1.5 4.0 3 2 0 3 3 3 0 4Fe-4S binding domain VSP PF03302.13 EGR31650.1 - 0.37 9.6 27.7 0.19 10.6 9.6 2.0 1 1 1 2 2 2 0 Giardia variant-specific surface protein MPS-4 PF17523.2 EGR31650.1 - 4.3 7.5 6.2 9.3 6.5 6.2 1.7 1 0 0 1 1 1 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Hydrolase_4 PF12146.8 EGR31652.1 - 5.4e-14 52.0 0.0 1.3e-10 41.0 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR31652.1 - 1.3e-13 51.2 0.1 3.6e-08 33.4 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EGR31652.1 - 1.5e-06 28.0 0.0 8.9e-06 25.5 0.0 2.2 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) PAF-AH_p_II PF03403.13 EGR31652.1 - 0.0002 20.0 0.7 0.011 14.2 0.0 2.5 3 0 0 3 3 3 2 Platelet-activating factor acetylhydrolase, isoform II BAAT_C PF08840.11 EGR31652.1 - 0.017 15.1 1.5 0.026 14.5 0.1 1.9 1 1 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.13 EGR31652.1 - 0.041 13.5 0.1 0.093 12.4 0.1 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) MORN PF02493.20 EGR31653.1 - 4.2e-44 145.9 76.6 3e-08 33.1 0.4 9.8 10 0 0 10 10 10 9 MORN repeat TTL PF03133.15 EGR31656.1 - 1.2e-62 211.8 21.9 1.1e-60 205.3 15.0 2.6 2 0 0 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR31656.1 - 1.1e-07 31.4 5.9 2e-06 27.3 0.1 3.2 3 1 0 3 3 3 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR31656.1 - 0.00035 19.9 2.7 0.044 13.0 0.0 3.1 3 1 1 4 4 4 2 Sugar-transfer associated ATP-grasp ABC_tran PF00005.27 EGR31657.1 - 2.4e-10 41.0 0.3 1.9e-09 38.1 0.0 2.5 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EGR31657.1 - 4.3e-10 39.9 1.1 3.6e-07 30.3 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGR31657.1 - 0.079 12.4 0.5 0.17 11.3 0.0 1.8 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain cNMP_binding PF00027.29 EGR31658.1 - 2.7e-11 43.4 0.0 7.3e-11 42.0 0.0 1.8 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGR31658.1 - 3.5e-09 36.5 7.9 3.5e-09 36.5 7.9 2.0 2 0 0 2 2 2 1 Ion channel Ion_trans PF00520.31 EGR31658.1 - 9.3e-07 28.3 10.3 9.3e-07 28.3 10.3 2.4 2 1 0 2 2 2 1 Ion transport protein IRK PF01007.20 EGR31658.1 - 0.048 13.5 9.1 0.14 12.0 8.4 2.3 1 1 1 2 2 2 0 Inward rectifier potassium channel transmembrane domain zf-CCHC_2 PF13696.6 EGR31658.1 - 0.31 10.9 4.8 0.84 9.5 4.8 1.8 1 0 0 1 1 1 0 Zinc knuckle PI3_PI4_kinase PF00454.27 EGR31659.1 - 2e-20 73.7 1.2 5.5e-14 52.6 0.4 2.7 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase Aldedh PF00171.22 EGR31662.1 - 4.6e-12 45.2 0.1 2.8e-09 36.0 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family Aldedh PF00171.22 EGR31663.1 - 2e-13 49.7 0.0 2.6e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family RCC1 PF00415.18 EGR31664.1 - 7.2e-90 295.5 18.8 4.2e-12 46.5 0.0 14.5 15 1 0 15 15 15 12 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR31664.1 - 3.5e-53 176.4 32.4 7.4e-08 32.0 0.2 12.3 12 0 0 12 12 12 11 Regulator of chromosome condensation (RCC1) repeat KRTAP PF11759.8 EGR31664.1 - 5.4 7.6 6.9 18 6.0 0.3 3.4 2 1 0 2 2 2 0 Keratin-associated matrix HU-CCDC81_euk_1 PF14908.6 EGR31665.1 - 8.2e-24 83.6 0.1 8.2e-24 83.6 0.1 3.3 3 0 0 3 3 3 1 CCDC81 eukaryotic HU domain 1 EF-hand_7 PF13499.6 EGR31665.1 - 3.9e-23 81.7 46.5 1.3e-06 28.8 3.9 10.3 9 1 1 10 10 10 7 EF-hand domain pair EF-hand_6 PF13405.6 EGR31665.1 - 6.3e-22 75.6 54.6 0.0024 17.7 0.9 13.2 13 0 0 13 13 13 9 EF-hand domain EF-hand_1 PF00036.32 EGR31665.1 - 3.5e-21 73.1 54.2 0.00034 19.9 0.8 11.9 12 0 0 12 12 12 7 EF hand EF-hand_8 PF13833.6 EGR31665.1 - 4.1e-14 52.2 25.8 1.1e-05 25.2 0.7 8.9 9 0 0 9 9 9 3 EF-hand domain pair HU-CCDC81_euk_2 PF18289.1 EGR31665.1 - 5e-10 39.4 0.8 1.4e-08 34.7 0.8 3.0 1 1 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 EF-hand_5 PF13202.6 EGR31665.1 - 4e-09 35.6 37.4 0.00035 19.9 2.0 7.0 6 0 0 6 6 6 4 EF hand LMBR1 PF04791.16 EGR31665.1 - 1.1e-07 31.2 9.3 1.1e-07 31.2 9.3 6.3 3 3 2 5 5 5 1 LMBR1-like membrane protein BAF PF02961.14 EGR31665.1 - 0.00084 19.7 0.4 0.0088 16.5 0.4 2.9 1 0 0 1 1 1 1 Barrier to autointegration factor Wzz PF02706.15 EGR31665.1 - 3.9 7.8 11.7 0.67 10.3 0.9 4.8 3 0 0 3 3 3 0 Chain length determinant protein PHM7_cyt PF14703.6 EGR31666.1 - 1.6e-07 31.7 10.4 1.6e-07 31.7 10.4 2.8 3 1 0 3 3 3 1 Cytosolic domain of 10TM putative phosphate transporter Peptidase_M16 PF00675.20 EGR31667.1 - 8.9e-36 123.1 1.5 2e-35 122.0 0.1 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGR31667.1 - 1.4e-21 77.3 0.4 1.4e-21 77.3 0.4 2.5 2 0 0 2 2 2 1 Peptidase M16 inactive domain AAA PF00004.29 EGR31667.1 - 9.4e-13 48.7 0.0 3.1e-12 47.1 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGR31667.1 - 6.3e-08 32.8 8.1 7.5e-07 29.2 4.8 3.3 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_2 PF07724.14 EGR31667.1 - 5.3e-05 23.4 0.0 0.00018 21.7 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGR31667.1 - 6.3e-05 23.4 0.0 0.00022 21.7 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EGR31667.1 - 7.2e-05 22.8 2.0 0.00016 21.7 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 EGR31667.1 - 0.00062 20.1 0.1 0.0066 16.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGR31667.1 - 0.0012 18.4 0.0 0.003 17.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_5 PF07728.14 EGR31667.1 - 0.002 18.1 0.0 0.0055 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_assoc_2 PF16193.5 EGR31667.1 - 0.0028 18.0 0.1 0.01 16.1 0.1 2.1 1 0 0 1 1 1 1 AAA C-terminal domain RuvB_N PF05496.12 EGR31667.1 - 0.0038 17.0 0.0 0.0077 16.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EGR31667.1 - 0.0056 15.9 0.1 0.014 14.5 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_11 PF13086.6 EGR31667.1 - 0.0081 16.0 0.0 0.0081 16.0 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_6 PF12774.7 EGR31667.1 - 0.01 14.9 0.0 0.01 14.9 0.0 2.8 3 0 0 3 3 3 0 Hydrolytic ATP binding site of dynein motor region RsgA_GTPase PF03193.16 EGR31667.1 - 0.011 15.7 0.1 0.052 13.5 0.1 2.1 1 1 1 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 EGR31667.1 - 0.011 16.3 0.0 0.038 14.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGR31667.1 - 0.015 15.6 0.0 0.03 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGR31667.1 - 0.034 14.1 0.1 6.7 6.6 0.1 2.6 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.22 EGR31667.1 - 0.046 14.1 0.0 0.23 11.9 0.0 2.3 1 0 0 1 1 1 0 RNA helicase AAA_30 PF13604.6 EGR31667.1 - 0.05 13.3 0.0 0.11 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGR31667.1 - 0.071 12.4 0.0 0.22 10.8 0.0 1.9 1 0 0 1 1 1 0 Zeta toxin AAA_19 PF13245.6 EGR31667.1 - 0.11 12.8 0.0 0.35 11.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain Hydin_ADK PF17213.3 EGR31667.1 - 0.34 11.1 4.3 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain GSHPx PF00255.19 EGR31669.1 - 1.1e-18 66.8 0.0 1.5e-18 66.3 0.0 1.2 1 0 0 1 1 1 1 Glutathione peroxidase Caleosin PF05042.13 EGR31669.1 - 0.11 12.4 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Caleosin related protein Hydantoinase_B PF02538.14 EGR31670.1 - 3.1e-191 636.3 0.0 3.6e-191 636.1 0.0 1.0 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase DUF1440 PF07274.12 EGR31670.1 - 0.025 14.9 0.0 0.046 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) Hydantoinase_A PF01968.18 EGR31671.1 - 1.6e-89 300.0 0.0 2.8e-89 299.2 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EGR31671.1 - 2e-55 187.3 1.5 2.8e-53 180.3 0.2 2.3 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region XTBD PF11952.8 EGR31671.1 - 0.025 14.3 0.0 0.076 12.8 0.0 1.8 1 0 0 1 1 1 0 XRN-Two Binding Domain, XTBD Peptidase_M8 PF01457.16 EGR31673.1 - 4.2e-13 48.8 2.8 9.1e-13 47.7 0.8 2.4 2 1 0 2 2 2 1 Leishmanolysin EGF_Tenascin PF18720.1 EGR31673.1 - 8.5e-08 32.1 9.2 8.5e-08 32.1 9.2 2.1 2 0 0 2 2 2 1 Tenascin EGF domain EGF_2 PF07974.13 EGR31673.1 - 0.0038 17.6 11.5 0.0038 17.6 11.5 2.3 3 0 0 3 3 3 1 EGF-like domain Peptidase_M8 PF01457.16 EGR31674.1 - 9e-41 140.1 11.2 5.7e-38 130.9 0.1 4.1 2 2 2 5 5 5 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR31674.1 - 3.9e-07 30.0 9.0 3.9e-07 30.0 9.0 5.5 5 0 0 5 5 5 1 Tenascin EGF domain Peptidase_C1 PF00112.23 EGR31675.1 - 9.8e-72 241.6 0.8 1.1e-71 241.4 0.8 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGR31675.1 - 5.4e-06 25.4 0.5 0.011 14.6 0.0 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Pkinase PF00069.25 EGR31676.1 - 4.7e-75 252.4 0.0 8.1e-75 251.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31676.1 - 1.8e-35 122.5 0.0 3.1e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 EGR31676.1 - 1.6e-30 102.4 10.1 1.1e-07 30.9 2.8 4.7 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGR31676.1 - 6.3e-27 93.8 6.6 6.6e-13 48.9 3.7 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR31676.1 - 2.4e-25 86.2 7.2 4.4e-07 29.3 0.1 4.9 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGR31676.1 - 1.6e-23 81.1 10.1 1.1e-05 24.7 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGR31676.1 - 1e-17 63.7 10.4 0.00022 21.0 0.0 4.6 1 1 3 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGR31676.1 - 2e-07 31.3 1.0 0.0042 17.4 0.7 2.8 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGR31676.1 - 6.3e-06 26.1 5.4 0.038 13.9 2.6 3.0 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Kdo PF06293.14 EGR31676.1 - 5.5e-05 22.6 0.0 0.00012 21.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Prefoldin_3 PF13758.6 EGR31676.1 - 8.4e-05 22.6 2.4 0.49 10.5 0.7 3.4 2 1 0 2 2 2 1 Prefoldin subunit Sigma54_CBD PF04963.13 EGR31676.1 - 0.0023 17.8 0.5 0.016 15.1 0.4 2.4 2 1 1 3 3 3 1 Sigma-54 factor, core binding domain APH PF01636.23 EGR31676.1 - 0.019 14.9 0.0 0.2 11.5 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family PMBR PF09373.10 EGR31676.1 - 0.034 14.3 0.0 1.1e+02 3.2 0.0 4.8 5 0 0 5 5 5 0 Pseudomurein-binding repeat EF-hand_10 PF14788.6 EGR31676.1 - 0.037 13.9 1.3 8.7 6.3 0.6 3.1 2 1 1 3 3 3 0 EF hand DUF4777 PF16007.5 EGR31676.1 - 0.053 13.8 0.2 0.51 10.6 0.0 2.6 4 0 0 4 4 2 0 Domain of unknown function (DUF4777) EF-hand_11 PF08976.11 EGR31676.1 - 0.065 14.1 0.0 0.31 12.0 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain LSDAT_prok PF18171.1 EGR31677.1 - 8.4e-12 44.7 0.0 1.7e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 SLOG in TRPM, prokaryote Ndc1_Nup PF09531.10 EGR31677.1 - 1.7 7.2 10.8 2 7.0 10.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 EGR31677.1 - 3.3 6.4 19.2 3.9 6.1 19.2 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 EGR31677.1 - 4.3 5.8 12.0 5 5.6 12.0 1.2 1 0 0 1 1 1 0 Macoilin family Stealth_CR3 PF17102.5 EGR31678.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Stealth protein CR3, conserved region 3 DUF3087 PF11286.8 EGR31678.1 - 0.027 13.9 1.6 0.027 13.9 1.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3087) TcpS PF17456.2 EGR31678.1 - 0.03 14.4 8.3 0.046 13.8 8.3 1.4 1 1 0 1 1 1 0 Toxin-coregulated pilus protein S Osmo_CC PF08946.10 EGR31678.1 - 0.11 12.7 0.2 0.11 12.7 0.2 2.5 3 0 0 3 3 3 0 Osmosensory transporter coiled coil DUF465 PF04325.13 EGR31678.1 - 0.13 12.4 11.5 0.54 10.3 2.4 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF465) Sec8_exocyst PF04048.14 EGR31678.1 - 0.18 11.7 8.0 0.36 10.7 8.0 1.5 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain Cob_adeno_trans PF01923.18 EGR31678.1 - 0.18 11.9 1.2 0.2 11.8 1.2 1.0 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Prefoldin_2 PF01920.20 EGR31678.1 - 0.21 11.6 14.2 0.19 11.7 3.3 2.1 1 1 1 2 2 2 0 Prefoldin subunit BLOC1_2 PF10046.9 EGR31678.1 - 0.41 11.0 10.7 3.1 8.2 4.5 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fib_alpha PF08702.10 EGR31678.1 - 1.7 8.9 11.1 2.3 8.4 11.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family AAA_23 PF13476.6 EGR31678.1 - 2.9 8.4 12.8 3.4 8.1 12.8 1.1 1 0 0 1 1 1 0 AAA domain Ribosomal_L30_N PF08079.12 EGR31678.1 - 4.6 7.6 10.5 0.14 12.5 4.3 1.7 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain Bromodomain PF00439.25 EGR31679.1 - 5.1e-21 74.5 0.8 2e-20 72.6 0.2 2.5 2 0 0 2 2 2 1 Bromodomain BET PF17035.5 EGR31679.1 - 1.7e-11 44.1 4.3 1.7e-11 44.1 4.3 2.3 2 0 0 2 2 2 1 Bromodomain extra-terminal - transcription regulation Atypical_Card PF18461.1 EGR31679.1 - 0.25 11.6 8.1 0.31 11.3 0.5 3.2 2 1 1 3 3 3 0 Atypical caspase recruitment domain DUF4539 PF15072.6 EGR31682.1 - 0.01 15.9 0.8 0.073 13.1 0.1 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4539) HATPase_c PF02518.26 EGR31683.1 - 1.9e-18 67.0 0.6 4.2e-18 65.9 0.6 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGR31683.1 - 1.4e-14 54.2 0.1 3.5e-14 52.9 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EGR31683.1 - 3.5e-09 36.6 0.5 7.5e-09 35.5 0.1 1.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EGR31683.1 - 8.8e-05 22.4 2.0 0.00078 19.3 0.9 2.6 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase MFS_1 PF07690.16 EGR31685.1 - 3.3e-16 59.2 16.1 9.2e-15 54.4 15.3 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Mem_trans PF03547.18 EGR31685.1 - 2.5e-07 29.4 3.8 4.5e-07 28.6 3.8 1.4 1 1 0 1 1 1 1 Membrane transport protein OATP PF03137.20 EGR31685.1 - 1.3e-06 27.0 13.2 0.0019 16.6 2.9 3.1 1 1 2 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family BT1 PF03092.16 EGR31685.1 - 3.9e-06 25.4 0.2 5.5e-06 24.9 0.2 1.3 1 0 0 1 1 1 1 BT1 family Connexin PF00029.19 EGR31685.1 - 0.00076 19.3 0.5 0.0014 18.5 0.5 1.5 1 0 0 1 1 1 1 Connexin SID-1_RNA_chan PF13965.6 EGR31685.1 - 0.00096 17.7 2.5 0.0014 17.1 2.5 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 Ctr PF04145.15 EGR31685.1 - 0.036 14.7 0.1 0.036 14.7 0.1 1.9 2 1 1 3 3 3 0 Ctr copper transporter family DUF2484 PF10658.9 EGR31685.1 - 1.4 9.3 10.2 7.3 7.0 0.1 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2484) Activator_LAG-3 PF11498.8 EGR31685.1 - 5.8 5.8 13.4 8.1 5.3 13.4 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Wzz PF02706.15 EGR31685.1 - 6 7.2 10.0 0.15 12.4 0.6 2.7 2 0 0 2 2 2 0 Chain length determinant protein p25-alpha PF05517.12 EGR31686.1 - 2.4e-38 131.7 8.6 2.7e-38 131.6 8.6 1.0 1 0 0 1 1 1 1 p25-alpha Pkinase PF00069.25 EGR31687.1 - 1.2e-23 83.8 0.8 5.4e-14 52.2 0.1 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31687.1 - 1e-09 38.1 0.2 0.00019 20.8 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR31687.1 - 4.6e-07 28.9 0.2 1.2e-05 24.3 0.1 2.1 1 1 1 2 2 2 1 Fungal protein kinase APH PF01636.23 EGR31687.1 - 2.9e-05 24.1 0.0 0.0076 16.2 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGR31687.1 - 0.0041 16.5 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGR31687.1 - 0.03 13.9 0.3 0.074 12.6 0.3 1.7 1 1 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 EGR31687.1 - 0.038 13.5 0.1 0.074 12.6 0.1 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Haspin_kinase PF12330.8 EGR31687.1 - 0.038 12.9 0.0 0.069 12.1 0.0 1.4 1 0 0 1 1 1 0 Haspin like kinase domain Oxidored_FMN PF00724.20 EGR31688.1 - 1.6e-79 267.7 0.0 1.8e-79 267.5 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Pribosyltran PF00156.27 EGR31689.1 - 7.7e-28 97.0 0.0 9.5e-28 96.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGR31689.1 - 0.00032 20.2 0.0 0.00045 19.7 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase QSregVF PF13652.6 EGR31689.1 - 0.076 13.0 0.2 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 Putative quorum-sensing-regulated virulence factor PRTase_2 PF15609.6 EGR31689.1 - 0.14 11.6 0.0 0.26 10.8 0.0 1.4 2 0 0 2 2 2 0 Phosphoribosyl transferase Pkinase PF00069.25 EGR31690.1 - 1.7e-69 234.2 0.7 2e-69 233.9 0.7 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31690.1 - 8.8e-41 139.9 0.0 1e-40 139.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31690.1 - 5.2e-10 39.1 0.0 9.2e-10 38.3 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR31690.1 - 0.00011 21.2 0.0 0.00017 20.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGR31690.1 - 0.00015 20.8 0.8 0.00017 20.7 0.8 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGR31690.1 - 0.00017 21.0 0.1 0.00032 20.1 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGR31690.1 - 0.0024 17.5 0.5 0.16 11.5 0.0 2.3 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Seadorna_VP7 PF07387.11 EGR31690.1 - 0.0052 15.9 0.0 0.012 14.7 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EGR31690.1 - 0.055 13.4 0.0 0.13 12.2 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family PX PF00787.24 EGR31692.1 - 5.4e-20 71.5 1.4 5.4e-20 71.5 1.4 2.1 2 0 0 2 2 2 1 PX domain YqbF PF14553.6 EGR31692.1 - 0.021 14.6 0.4 0.057 13.3 0.4 1.7 1 0 0 1 1 1 0 YqbF, hypothetical protein domain Pkinase PF00069.25 EGR31693.1 - 1.7e-62 211.2 1.0 2.1e-62 210.9 1.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31693.1 - 2.8e-32 112.0 0.2 1.7e-31 109.4 0.2 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR31693.1 - 1.4e-05 24.2 1.1 2.5e-05 23.4 0.2 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EGR31693.1 - 6.3e-05 22.4 0.0 9.5e-05 21.8 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 EGR31693.1 - 0.00079 19.4 0.0 0.0048 16.9 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGR31693.1 - 0.0052 16.4 0.2 0.015 14.9 0.2 1.7 1 1 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGR31693.1 - 0.0068 15.8 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_12 PF13424.6 EGR31694.1 - 3e-17 62.7 0.7 2.1e-13 50.4 0.3 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGR31694.1 - 6.5e-12 44.9 2.0 0.0002 21.1 0.1 3.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGR31694.1 - 1.2e-07 31.3 2.6 0.00021 21.2 0.1 3.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGR31694.1 - 8.1e-07 28.6 1.5 0.0002 21.1 0.2 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGR31694.1 - 4.7e-06 26.4 5.5 0.0049 17.0 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_3 PF07720.12 EGR31694.1 - 2.9e-05 23.9 0.9 0.032 14.2 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGR31694.1 - 0.00016 21.3 7.1 0.012 15.4 0.6 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGR31694.1 - 0.0094 15.6 5.3 0.065 12.9 1.1 3.1 3 0 0 3 3 3 1 TPR repeat DUF4844 PF16133.5 EGR31694.1 - 0.047 14.2 0.1 0.058 13.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4844) UPF0122 PF04297.14 EGR31694.1 - 0.084 13.1 2.3 0.2 11.9 0.1 2.1 1 1 1 2 2 2 0 Putative helix-turn-helix protein, YlxM / p13 like DUF4058 PF13267.6 EGR31694.1 - 0.087 12.2 1.1 0.3 10.5 0.9 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4058) TPR_14 PF13428.6 EGR31694.1 - 0.12 13.3 0.0 1.9 9.5 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGR31694.1 - 0.17 12.6 0.0 1.4 9.6 0.0 2.2 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EGR31694.1 - 0.6 10.2 6.5 0.51 10.4 1.7 2.6 2 1 1 3 3 3 0 MIT (microtubule interacting and transport) domain Mito_carr PF00153.27 EGR31695.1 - 1.6e-71 236.3 4.6 3.2e-26 91.1 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Fuseless PF15993.5 EGR31695.1 - 0.00053 19.3 0.1 0.00091 18.5 0.1 1.4 1 0 0 1 1 1 1 Fuseless DEAD PF00270.29 EGR31696.1 - 7.7e-47 159.3 0.8 1.6e-46 158.3 0.2 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR31696.1 - 3.4e-26 91.8 7.7 3.4e-26 91.7 0.0 4.1 5 1 1 6 6 6 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGR31696.1 - 1.5e-14 53.9 0.3 3.1e-14 52.9 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) FAM183 PF14886.6 EGR31696.1 - 0.037 14.8 1.2 0.037 14.8 1.2 1.9 2 0 0 2 2 2 0 FAM183A and FAM183B related AAA_22 PF13401.6 EGR31696.1 - 0.08 13.2 0.9 0.45 10.8 0.9 2.4 1 1 0 1 1 1 0 AAA domain Ribosomal_S17 PF00366.20 EGR31697.1 - 3.7e-23 81.4 3.1 8e-23 80.3 3.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S17 DUF999 PF06198.11 EGR31697.1 - 0.0093 16.0 1.8 0.011 15.7 0.9 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF999) Serpin PF00079.20 EGR31698.1 - 9.6e-41 140.3 10.4 1.2e-40 139.9 10.4 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Herpes_U34 PF04541.13 EGR31698.1 - 0.027 13.7 0.4 0.027 13.7 0.4 1.6 2 0 0 2 2 2 0 Herpesvirus virion protein U34 SIMPL PF04402.14 EGR31699.1 - 1.5e-37 130.0 19.3 3.9e-22 79.7 4.2 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF541) Aldo_ket_red PF00248.21 EGR31699.1 - 0.00074 18.8 7.0 0.00091 18.5 1.8 2.4 2 1 1 3 3 3 1 Aldo/keto reductase family DUF442 PF04273.13 EGR31699.1 - 0.0021 18.1 0.1 1.1 9.4 0.1 2.4 2 0 0 2 2 2 2 Putative phosphatase (DUF442) LPD7 PF18821.1 EGR31699.1 - 0.0037 17.3 1.1 0.98 9.6 0.1 3.3 3 1 1 4 4 4 1 Large polyvalent protein-associated domain 7 NIR_SIR PF01077.22 EGR31699.1 - 0.019 14.5 0.7 0.041 13.4 0.7 1.5 1 0 0 1 1 1 0 Nitrite and sulphite reductase 4Fe-4S domain Methyltr_RsmB-F PF01189.17 EGR31699.1 - 0.02 14.5 6.9 0.23 11.1 0.4 2.4 1 1 1 2 2 2 0 16S rRNA methyltransferase RsmB/F DUF4170 PF13773.6 EGR31699.1 - 0.14 12.4 0.4 15 5.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4170) YajC PF02699.15 EGR31699.1 - 0.25 11.2 2.1 0.91 9.4 0.2 2.7 2 0 0 2 2 2 0 Preprotein translocase subunit YbaB_DNA_bd PF02575.16 EGR31699.1 - 0.3 11.4 8.4 1.8 8.8 1.9 3.6 3 1 0 3 3 3 0 YbaB/EbfC DNA-binding family Lsr2 PF11774.8 EGR31699.1 - 0.69 10.1 4.6 0.59 10.3 0.4 2.8 2 1 1 3 3 3 0 Lsr2 DUF406 PF04175.12 EGR31699.1 - 0.69 10.4 11.2 2.4 8.7 0.2 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF406) DUF5511 PF17630.2 EGR31699.1 - 4.5 7.5 8.8 0.9 9.8 1.3 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF5511) PAH PF02671.21 EGR31700.1 - 0.11 12.7 3.4 4.5 7.5 0.0 2.3 2 0 0 2 2 2 0 Paired amphipathic helix repeat WD40 PF00400.32 EGR31701.1 - 2e-39 132.8 16.3 3.5e-05 24.5 0.0 12.3 13 0 0 13 13 13 8 WD domain, G-beta repeat HELP PF03451.14 EGR31701.1 - 1.4e-25 88.9 0.0 3.1e-25 87.8 0.0 1.6 1 0 0 1 1 1 1 HELP motif ANAPC4_WD40 PF12894.7 EGR31701.1 - 5.5e-13 49.0 0.4 0.02 15.2 0.0 7.9 5 3 4 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGR31701.1 - 8.4e-06 25.0 1.8 0.16 10.9 0.0 5.2 4 1 3 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Peptidase_M76 PF09768.9 EGR31701.1 - 0.13 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Peptidase M76 family HELP PF03451.14 EGR31702.1 - 2.2e-26 91.5 0.1 3.8e-15 55.5 0.0 2.6 2 0 0 2 2 2 2 HELP motif WD40 PF00400.32 EGR31702.1 - 2.4e-19 69.3 25.7 0.014 16.2 0.1 12.8 14 0 0 14 14 14 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR31702.1 - 4.7e-09 36.4 1.6 0.031 14.6 0.0 6.1 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EGR31702.1 - 0.00084 18.0 0.3 0.65 8.5 0.0 2.7 3 0 0 3 3 3 2 Cytochrome D1 heme domain EF-hand_1 PF00036.32 EGR31702.1 - 0.00085 18.7 1.1 0.0019 17.6 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EGR31702.1 - 0.0094 15.8 1.2 0.025 14.5 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain CarD_CdnL_TRCF PF02559.16 EGR31702.1 - 0.016 15.9 0.0 0.072 13.8 0.0 2.2 1 0 0 1 1 1 0 CarD-like/TRCF domain EF-hand_7 PF13499.6 EGR31702.1 - 0.057 13.9 0.0 0.2 12.1 0.0 1.9 1 0 0 1 1 1 0 EF-hand domain pair Peptidase_C97 PF05903.14 EGR31704.1 - 6.9e-41 139.6 0.0 8.4e-41 139.3 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain Peptidase_C1 PF00112.23 EGR31705.1 - 5.9e-70 235.8 4.2 1e-69 234.9 4.2 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGR31705.1 - 5.2e-09 36.4 3.8 1.3e-08 35.2 3.8 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGR31705.1 - 0.0083 14.9 4.6 0.45 9.2 0.2 2.5 3 0 0 3 3 3 2 Peptidase C1-like family ERGIC_N PF13850.6 EGR31706.1 - 0.0024 18.2 0.5 0.0024 18.2 0.5 3.1 4 0 0 4 4 4 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF1242 PF06842.12 EGR31707.1 - 1.5e-13 50.3 0.6 2.8e-13 49.4 0.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) WD40 PF00400.32 EGR31708.1 - 4.5e-05 24.1 1.7 0.13 13.1 0.1 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat EF-hand_7 PF13499.6 EGR31708.1 - 0.02 15.3 0.1 0.055 13.9 0.1 1.9 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.32 EGR31708.1 - 0.055 13.0 0.3 0.16 11.6 0.3 1.8 1 0 0 1 1 1 0 EF hand WD40 PF00400.32 EGR31709.1 - 1.1e-11 45.1 1.8 0.088 13.7 0.2 4.9 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR31709.1 - 3.9e-07 30.3 0.3 0.0029 17.9 0.0 3.0 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_7 PF13499.6 EGR31710.1 - 4.7e-13 49.4 0.6 8.2e-13 48.6 0.1 1.6 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGR31710.1 - 1.4e-10 39.9 0.1 0.00073 18.9 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGR31710.1 - 3e-09 35.9 0.7 2.5e-05 23.6 0.0 3.0 3 1 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EGR31710.1 - 1.5e-07 30.8 0.2 0.0018 18.1 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGR31710.1 - 3.3e-07 30.0 0.2 0.0073 16.1 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.6 EGR31710.1 - 0.0035 17.2 0.1 0.031 14.1 0.0 2.3 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 EGR31710.1 - 0.11 12.8 0.1 0.59 10.5 0.1 2.1 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region PrpF PF04303.13 EGR31711.1 - 8.8e-88 294.8 0.0 1.1e-87 294.5 0.0 1.0 1 0 0 1 1 1 1 PrpF protein GCP_N_terminal PF17681.1 EGR31712.1 - 2.5e-61 208.0 6.7 2.5e-61 208.0 6.7 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EGR31712.1 - 9.9e-61 205.9 23.5 1.9e-60 204.9 18.9 2.3 2 1 0 2 2 2 1 Gamma tubulin complex component C-terminal Macin PF14865.6 EGR31712.1 - 0.13 12.8 1.7 9.2 6.9 0.9 2.5 2 0 0 2 2 2 0 Macin Porin_2 PF02530.14 EGR31713.1 - 0.012 14.9 0.7 0.012 14.9 0.7 1.1 1 0 0 1 1 1 0 Porin subfamily ATP-synt_ab PF00006.25 EGR31715.1 - 2.2e-62 210.5 0.0 3e-62 210.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGR31715.1 - 5.1e-23 81.4 2.5 9.9e-23 80.4 2.5 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain NB-ARC PF00931.22 EGR31715.1 - 0.0053 16.0 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.6 EGR31715.1 - 0.016 15.6 0.7 0.18 12.1 0.1 2.4 2 1 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 EGR31715.1 - 0.026 14.5 0.0 0.061 13.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 EGR31715.1 - 0.029 14.3 0.0 0.065 13.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 EGR31715.1 - 0.039 13.9 0.0 0.094 12.6 0.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea AAA PF00004.29 EGR31715.1 - 0.11 12.9 0.1 0.48 10.8 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGR31715.1 - 0.12 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 EGR31715.1 - 0.13 11.5 0.1 0.38 10.1 0.1 1.8 1 0 0 1 1 1 0 KaiC AAA_22 PF13401.6 EGR31715.1 - 0.15 12.4 0.1 0.64 10.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EGR31715.1 - 0.15 12.4 1.0 0.32 11.3 0.1 2.0 3 0 0 3 3 3 0 AAA domain Pkinase PF00069.25 EGR31716.1 - 4.7e-65 219.6 3.3 4.7e-65 219.6 3.3 2.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31716.1 - 5.7e-41 140.5 1.1 1.6e-40 139.0 1.1 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR31716.1 - 0.015 15.3 0.0 4.5 7.1 0.0 2.2 1 1 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_L28e PF01778.17 EGR31717.1 - 2.8e-16 60.3 1.6 3.6e-16 59.9 1.6 1.2 1 0 0 1 1 1 1 Ribosomal L28e protein family EF-hand_8 PF13833.6 EGR31718.1 - 0.00017 21.3 0.4 0.001 18.9 0.0 2.5 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 EGR31718.1 - 0.0014 18.4 1.7 1.7 8.8 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 EGR31718.1 - 0.01 16.3 1.8 0.61 10.6 0.0 2.4 1 1 1 2 2 2 0 EF-hand domain pair DUF4869 PF16163.5 EGR31718.1 - 0.074 12.8 1.5 0.089 12.5 0.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4869) Vps39_1 PF10366.9 EGR31718.1 - 0.11 12.8 1.1 0.41 10.9 0.2 2.1 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 1 Peptidase_M99_m PF17130.4 EGR31718.1 - 0.13 12.2 0.0 0.22 11.5 0.0 1.4 1 0 0 1 1 1 0 beta-barrel domain of carboxypeptidase M99 EF-hand_1 PF00036.32 EGR31718.1 - 0.25 11.0 0.0 0.25 11.0 0.0 3.9 4 1 0 4 4 4 0 EF hand MetOD2 PF18548.1 EGR31719.1 - 8 6.6 15.9 3.7 7.7 0.9 4.2 4 0 0 4 4 4 0 Metanogen output domain 2 zf-CCCH PF00642.24 EGR31720.1 - 2.5e-11 43.2 17.0 5e-08 32.7 4.4 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGR31720.1 - 8e-06 25.7 21.1 0.0002 21.3 7.2 2.6 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 EGR31720.1 - 0.0076 16.9 21.9 0.027 15.2 2.7 3.3 2 1 1 3 3 3 2 Torus domain zf-CCCH_2 PF14608.6 EGR31720.1 - 0.011 16.2 3.8 0.011 16.2 3.8 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 EGR31720.1 - 0.014 15.2 4.5 0.014 15.2 4.5 2.5 2 0 0 2 2 2 0 CCCH-type zinc finger EF-hand_7 PF13499.6 EGR31721.1 - 6.9e-05 23.2 3.8 0.00011 22.6 0.3 2.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EGR31721.1 - 0.00011 21.5 2.3 0.0012 18.3 0.2 3.1 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 EGR31721.1 - 0.0011 18.7 0.5 0.034 14.1 0.1 3.4 2 1 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 EGR31721.1 - 0.014 15.3 0.2 0.19 11.6 0.1 2.7 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_14 PF17959.1 EGR31721.1 - 0.069 13.5 0.2 0.069 13.5 0.2 3.2 3 1 1 4 4 4 0 EF-hand domain PhetRS_B1 PF18262.1 EGR31721.1 - 0.15 12.3 2.1 0.2 11.9 0.2 2.2 2 0 0 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain TIR_3 PF18567.1 EGR31723.1 - 0.037 14.0 2.5 0.045 13.7 2.5 1.1 1 0 0 1 1 1 0 Toll/interleukin-1 receptor domain RPAP3_C PF13877.6 EGR31723.1 - 0.13 12.8 2.8 0.17 12.4 2.8 1.2 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 Metallothio_Euk PF12749.7 EGR31724.1 - 3.2e-06 27.2 186.5 0.013 15.7 49.8 5.2 1 1 4 5 5 5 4 Eukaryotic metallothionein F-actin_cap_A PF01267.17 EGR31725.1 - 1.2e-47 162.6 5.5 1.1e-33 116.9 1.1 2.1 1 1 1 2 2 2 2 F-actin capping protein alpha subunit TTL PF03133.15 EGR31726.1 - 4.7e-82 275.4 10.0 5.4e-82 275.2 10.0 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR31726.1 - 2.6e-10 40.0 1.1 0.0025 17.1 0.0 3.4 2 2 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR31726.1 - 2.9e-08 33.3 0.2 0.0034 16.7 0.0 3.0 2 2 1 3 3 3 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 EGR31726.1 - 0.00011 21.8 0.1 0.0061 16.2 0.1 2.3 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 EGR31726.1 - 0.00073 19.6 0.0 0.015 15.4 0.0 2.2 2 0 0 2 2 2 1 ATP-grasp domain MMACHC PF16690.5 EGR31726.1 - 0.027 14.1 0.3 0.063 12.9 0.3 1.6 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type C family ATP-grasp_4 PF13535.6 EGR31726.1 - 0.14 11.7 0.4 6.9 6.2 0.0 2.2 2 0 0 2 2 2 0 ATP-grasp domain Pur_ac_phosph_N PF16656.5 EGR31727.1 - 0.00026 21.5 1.0 0.66 10.6 0.1 3.0 2 0 0 2 2 2 2 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 EGR31727.1 - 0.21 11.9 2.8 13 6.2 0.1 3.5 3 0 0 3 3 3 0 Fibronectin type III domain Interfer-bind PF09294.10 EGR31727.1 - 1.2 9.5 8.1 0.16 12.3 0.3 3.5 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III Pyridoxal_deC PF00282.19 EGR31728.1 - 2.1e-58 197.8 0.0 2.6e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 EGR31728.1 - 0.00019 20.8 0.0 0.00025 20.4 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EGR31728.1 - 0.0015 17.6 0.0 0.0025 16.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V OKR_DC_1 PF01276.20 EGR31728.1 - 0.01 14.6 0.0 0.02 13.7 0.0 1.4 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, major domain Dynein_C PF18199.1 EGR31728.1 - 0.081 12.1 0.0 0.16 11.2 0.0 1.4 1 0 0 1 1 1 0 Dynein heavy chain C-terminal domain RCC1 PF00415.18 EGR31729.1 - 1.9e-36 124.5 3.7 4.3e-11 43.3 0.1 5.0 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR31729.1 - 2.5e-08 33.5 10.1 0.031 14.1 0.5 5.2 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat DrrA_P4M PF14860.6 EGR31729.1 - 0.052 13.4 0.4 0.11 12.3 0.4 1.5 1 0 0 1 1 1 0 DrrA phosphatidylinositol 4-phosphate binding domain Pkinase PF00069.25 EGR31731.1 - 1.9e-49 168.4 0.1 7.3e-49 166.5 0.1 2.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31731.1 - 1.7e-28 99.6 0.1 6.9e-28 97.6 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Cyclin_N PF00134.23 EGR31731.1 - 1.3e-27 96.1 6.7 1.3e-27 96.1 6.7 3.1 3 0 0 3 3 3 1 Cyclin, N-terminal domain F-box PF00646.33 EGR31731.1 - 0.0036 17.1 0.0 0.0097 15.8 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGR31731.1 - 0.011 15.7 0.0 0.036 14.0 0.0 2.0 2 0 0 2 2 2 0 F-box-like Kinesin PF00225.23 EGR31732.1 - 3.2e-89 299.2 5.0 3.2e-89 299.2 5.0 2.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGR31732.1 - 3.6e-28 98.4 3.1 3.6e-28 98.4 3.1 3.5 3 1 0 3 3 3 1 Microtubule binding GFD1 PF17331.2 EGR31732.1 - 0.18 12.0 5.8 0.16 12.2 2.9 2.6 2 0 0 2 2 2 0 GFD1 mRNA transport factor Arg_decarb_HB PF17810.1 EGR31732.1 - 0.26 11.5 4.0 3.9 7.8 0.0 4.1 5 0 0 5 5 5 0 Arginine decarboxylase helical bundle domain Med9 PF07544.13 EGR31732.1 - 0.35 11.0 31.8 0.057 13.5 2.7 4.5 3 2 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 ACP_PD PF04336.12 EGR31732.1 - 3.5 8.1 10.8 0.16 12.4 2.8 3.0 3 0 0 3 3 3 0 Acyl carrier protein phosphodiesterase tRNA-synt_2b PF00587.25 EGR31733.1 - 2.2e-29 102.7 0.0 4.3e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_SAD PF07973.14 EGR31733.1 - 1.2e-10 41.3 0.0 3.7e-10 39.7 0.0 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EGR31733.1 - 0.0018 18.3 0.0 0.01 15.9 0.0 2.2 1 1 0 1 1 1 1 TGS domain PQ-loop PF04193.14 EGR31734.1 - 2.2e-27 94.6 11.9 4.5e-13 48.8 0.2 2.9 2 0 0 2 2 2 2 PQ loop repeat ADK PF00406.22 EGR31735.1 - 7.8e-19 68.3 8.9 4.2e-11 43.2 0.1 7.0 7 1 0 7 7 6 2 Adenylate kinase AAA_18 PF13238.6 EGR31735.1 - 3.4e-14 53.5 10.4 5.8e-07 30.1 0.0 6.6 6 0 0 6 6 6 2 AAA domain AAA_17 PF13207.6 EGR31735.1 - 1.1e-12 48.5 17.5 4.5e-05 23.9 0.1 7.1 7 1 0 7 7 6 4 AAA domain YHS PF04945.13 EGR31735.1 - 1.5e-07 31.3 1.2 0.21 11.7 0.1 4.7 4 0 0 4 4 4 2 YHS domain AAA_33 PF13671.6 EGR31735.1 - 1.3e-06 28.6 0.0 0.062 13.5 0.0 4.8 4 1 0 4 4 4 1 AAA domain AAA_24 PF13479.6 EGR31735.1 - 4.9e-06 26.4 5.0 0.26 11.0 0.0 4.4 5 0 0 5 5 5 2 AAA domain AAA_14 PF13173.6 EGR31735.1 - 0.0006 19.9 3.9 0.34 11.0 0.0 5.7 4 0 0 4 4 3 1 AAA domain AAA PF00004.29 EGR31735.1 - 0.0013 19.2 0.0 2.6 8.5 0.0 4.3 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGR31735.1 - 0.0048 17.2 0.0 7.9 6.7 0.0 4.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EGR31735.1 - 0.0055 17.1 0.1 36 4.8 0.0 4.6 3 0 0 3 3 3 0 RNA helicase MMR_HSR1 PF01926.23 EGR31735.1 - 0.0076 16.3 0.1 12 6.0 0.1 4.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase Cytidylate_kin PF02224.18 EGR31735.1 - 0.0093 15.7 0.8 2.1 8.1 0.0 4.1 4 0 0 4 4 4 1 Cytidylate kinase AAA_28 PF13521.6 EGR31735.1 - 0.0099 16.1 0.3 9.7 6.4 0.0 4.1 5 0 0 5 5 4 1 AAA domain AAA_29 PF13555.6 EGR31735.1 - 0.042 13.6 0.0 57 3.6 0.0 4.0 4 0 0 4 4 4 0 P-loop containing region of AAA domain DUF5319 PF17252.2 EGR31735.1 - 0.15 12.3 5.3 0.045 14.0 0.9 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5319) Pkinase PF00069.25 EGR31736.1 - 4.2e-60 203.3 1.5 6e-59 199.6 0.1 2.3 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31736.1 - 5.2e-42 143.9 0.3 9.3e-41 139.8 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR31736.1 - 6.2e-05 22.0 4.3 8.5e-05 21.5 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGR31736.1 - 0.0021 17.5 0.0 0.0041 16.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR31736.1 - 0.024 14.0 0.2 0.044 13.1 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR31736.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family EBP PF05241.12 EGR31737.1 - 1.1e-10 41.3 1.4 1.3e-10 41.0 1.4 1.1 1 0 0 1 1 1 1 Emopamil binding protein DHHC PF01529.20 EGR31737.1 - 0.055 13.6 2.1 0.074 13.2 2.1 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase CxxCxxCC PF03692.15 EGR31738.1 - 0.016 15.9 0.5 0.036 14.7 0.2 1.7 2 0 0 2 2 2 0 Putative zinc- or iron-chelating domain MORN PF02493.20 EGR31739.1 - 7.1e-19 66.5 29.3 9e-06 25.3 0.1 5.5 6 0 0 6 6 6 5 MORN repeat RHD3 PF05879.12 EGR31740.1 - 4.1e-54 184.0 44.8 4.1e-54 184.0 44.8 2.0 1 1 1 2 2 2 2 Root hair defective 3 GTP-binding protein (RHD3) Pkinase PF00069.25 EGR31741.1 - 5.3e-74 248.9 0.3 5.3e-74 248.9 0.3 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31741.1 - 1.7e-45 155.3 0.0 1.3e-44 152.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase POLO_box PF00659.18 EGR31741.1 - 3.9e-21 75.0 0.1 1.4e-20 73.3 0.1 2.0 1 0 0 1 1 1 1 POLO box duplicated region Kinase-like PF14531.6 EGR31741.1 - 1.7e-11 44.0 0.0 6e-09 35.6 0.0 3.0 2 1 1 3 3 3 2 Kinase-like SCP2 PF02036.17 EGR31741.1 - 0.024 15.1 0.1 4.4 7.9 0.0 2.5 2 0 0 2 2 2 0 SCP-2 sterol transfer family DUF4326 PF14216.6 EGR31741.1 - 0.63 10.8 5.4 12 6.7 0.7 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4326) Furin-like_2 PF15913.5 EGR31742.1 - 1e-102 337.6 1269.5 7.7e-08 32.5 24.6 58.3 2 2 59 61 61 61 51 Furin-like repeat, cysteine-rich GF_recep_IV PF14843.6 EGR31742.1 - 1.5e-47 160.6 1257.2 1.3e-05 25.0 38.6 41.9 2 2 39 41 41 41 26 Growth factor receptor domain IV VSP PF03302.13 EGR31742.1 - 8.3e-23 80.9 1114.2 0.00071 18.5 17.5 46.2 2 2 43 46 46 46 32 Giardia variant-specific surface protein GF_recep_IV PF14843.6 EGR31743.1 - 3.2e-37 127.3 766.9 7e-06 25.9 26.8 28.2 3 2 27 30 30 30 23 Growth factor receptor domain IV Furin-like_2 PF15913.5 EGR31743.1 - 2.6e-27 95.1 751.1 1.2e-06 28.6 19.6 34.0 2 1 32 34 34 34 25 Furin-like repeat, cysteine-rich Ion_trans PF00520.31 EGR31744.1 - 6.1e-16 58.4 23.0 1e-15 57.7 23.0 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EGR31744.1 - 2.9e-13 49.7 0.1 5.8e-13 48.7 0.1 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGR31744.1 - 4.2e-13 49.0 6.3 4.2e-13 49.0 6.3 2.2 2 1 0 2 2 2 1 Ion channel GCP_C_terminal PF04130.13 EGR31745.1 - 2e-10 40.7 0.0 2e-10 40.7 0.0 1.1 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal EGF_Tenascin PF18720.1 EGR31746.1 - 3e-08 33.5 6.8 3e-08 33.5 6.8 3.9 4 0 0 4 4 4 1 Tenascin EGF domain EGF_2 PF07974.13 EGR31746.1 - 0.016 15.6 17.2 0.016 15.6 17.2 5.5 3 3 0 3 3 3 0 EGF-like domain SHIPPO-rpt PF07004.12 EGR31747.1 - 1.4e-22 79.4 60.7 0.0001 23.0 0.1 10.8 9 2 1 10 10 10 8 Sperm-tail PG-rich repeat DUF2072 PF09845.9 EGR31747.1 - 0.12 12.6 0.7 1.4 9.2 0.0 2.7 2 1 1 3 3 3 0 Zn-ribbon containing protein Copine PF07002.16 EGR31748.1 - 4.3e-66 222.5 0.2 9.5e-66 221.4 0.2 1.6 1 0 0 1 1 1 1 Copine C2 PF00168.30 EGR31748.1 - 1.3e-08 35.0 0.5 0.00074 19.8 0.1 2.8 1 1 2 3 3 3 2 C2 domain vWA-TerF-like PF10138.9 EGR31748.1 - 0.00042 20.5 0.2 0.0018 18.4 0.2 2.2 1 1 0 1 1 1 1 vWA found in TerF C terminus Flavodoxin_3 PF12641.7 EGR31748.1 - 0.017 14.8 1.0 0.036 13.8 1.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain MRP-S27 PF10037.9 EGR31748.1 - 0.26 10.1 6.7 0.44 9.4 6.7 1.3 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 PRIMA1 PF16101.5 EGR31748.1 - 2.4 8.2 4.5 4.6 7.3 4.5 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Helicase_C PF00271.31 EGR31749.1 - 1.8e-18 66.9 0.1 4.5e-18 65.6 0.1 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 EGR31749.1 - 2.4e-05 23.7 1.6 3.7e-05 23.1 1.6 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HDA2-3 PF11496.8 EGR31749.1 - 3.3e-05 23.2 0.5 5.6e-05 22.5 0.5 1.4 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PP2C PF00481.21 EGR31750.1 - 1.3e-13 51.2 0.0 1.4e-13 51.1 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.25 EGR31753.1 - 4e-64 216.5 5.6 6.7e-64 215.8 5.6 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31753.1 - 6.8e-41 140.3 0.7 8.8e-40 136.6 0.7 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR31753.1 - 8.8e-06 25.2 0.2 1.8e-05 24.2 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR31753.1 - 0.0064 15.3 0.5 0.008 15.0 0.5 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR31753.1 - 0.041 13.8 0.0 0.06 13.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family HECT PF00632.25 EGR31754.1 - 1e-71 242.0 4.1 1.2e-71 241.7 4.1 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Recep_L_domain PF01030.24 EGR31754.1 - 0.037 14.1 1.5 0.087 12.9 1.5 1.6 1 0 0 1 1 1 0 Receptor L domain B PF02216.16 EGR31754.1 - 3.1 7.9 6.3 4.6 7.3 0.2 3.3 3 1 0 3 3 3 0 B domain DUF1126 PF06565.12 EGR31755.1 - 3.2e-62 206.9 8.4 1.9e-27 95.1 0.7 3.3 3 0 0 3 3 3 3 DUF1126 PH-like domain Helicase_C PF00271.31 EGR31756.1 - 1.9e-33 115.1 0.0 5.4e-33 113.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGR31756.1 - 1.6e-24 86.7 0.1 7.7e-24 84.4 0.0 2.2 2 1 1 3 3 3 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EGR31756.1 - 4.4e-05 22.8 0.1 8.6e-05 21.9 0.1 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase SNF2_N PF00176.23 EGR31756.1 - 0.045 12.5 0.4 3.3 6.3 0.1 2.3 1 1 1 2 2 2 0 SNF2 family N-terminal domain Lipoprotein_9 PF03180.14 EGR31756.1 - 0.12 11.4 0.1 0.12 11.4 0.1 2.2 2 0 0 2 2 2 0 NLPA lipoprotein zf-C2H2_10 PF16588.5 EGR31756.1 - 0.22 11.3 4.0 0.47 10.2 4.0 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger SHIPPO-rpt PF07004.12 EGR31757.1 - 1.7e-31 107.6 82.2 0.00011 22.9 1.2 12.4 12 0 0 12 12 12 12 Sperm-tail PG-rich repeat ECR1_N PF14382.6 EGR31757.1 - 1.7e-09 37.3 3.5 3.1 7.7 0.0 8.0 8 1 0 8 8 8 4 Exosome complex exonuclease RRP4 N-terminal region GIT1_C PF12205.8 EGR31758.1 - 0.13 12.4 0.1 0.13 12.4 0.1 1.7 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term ABC_membrane PF00664.23 EGR31759.1 - 6.8e-46 157.1 7.3 1.1e-45 156.4 7.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGR31759.1 - 4.9e-12 46.5 0.0 4.9e-12 46.5 0.0 3.4 2 1 1 3 3 2 1 ABC transporter AAA_29 PF13555.6 EGR31759.1 - 0.00059 19.5 0.0 0.0013 18.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGR31759.1 - 0.0028 17.6 0.0 0.017 15.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EGR31759.1 - 0.0033 17.8 1.9 0.0064 16.9 0.0 2.4 3 1 0 3 3 3 1 AAA ATPase domain AAA_15 PF13175.6 EGR31759.1 - 0.0061 16.3 0.1 0.0061 16.3 0.1 3.6 2 1 0 2 2 1 1 AAA ATPase domain AAA_22 PF13401.6 EGR31759.1 - 0.0062 16.8 2.2 0.036 14.3 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_21 PF13304.6 EGR31759.1 - 0.012 15.4 0.0 0.012 15.4 0.0 2.4 2 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGR31759.1 - 0.016 15.7 0.0 0.016 15.7 0.0 3.6 2 1 0 2 2 1 0 AAA domain AAA_30 PF13604.6 EGR31759.1 - 0.022 14.5 0.0 0.045 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGR31759.1 - 0.057 13.4 0.0 0.19 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 EGR31759.1 - 0.1 12.7 0.4 0.55 10.3 0.0 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase CAMSAP_CH PF11971.8 EGR31759.1 - 0.11 12.4 1.6 0.24 11.3 0.2 2.3 2 0 0 2 2 2 0 CAMSAP CH domain AAA_18 PF13238.6 EGR31759.1 - 0.14 12.7 0.0 0.14 12.7 0.0 3.2 2 1 1 3 3 3 0 AAA domain DUF87 PF01935.17 EGR31759.1 - 2 8.5 0.0 2 8.5 0.0 3.0 2 1 1 3 3 3 0 Helicase HerA, central domain Ras PF00071.22 EGR31760.1 - 4.8e-55 185.6 0.2 6.8e-55 185.1 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR31760.1 - 1.3e-35 122.2 0.0 2.7e-35 121.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR31760.1 - 1.2e-18 67.2 0.3 1.7e-18 66.7 0.3 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR31760.1 - 3.1e-08 33.7 0.0 6.6e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGR31760.1 - 9.8e-08 32.1 0.1 0.0091 15.9 0.0 2.4 2 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EGR31760.1 - 2.6e-06 27.0 0.1 4e-06 26.4 0.1 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGR31760.1 - 8.7e-06 25.4 0.0 9.9e-05 22.0 0.0 2.3 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EGR31760.1 - 8.9e-05 22.6 1.1 0.0018 18.4 1.1 2.7 1 1 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 EGR31760.1 - 9.4e-05 22.0 0.2 0.00084 18.9 0.2 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.10 EGR31760.1 - 0.00093 18.7 0.1 0.0032 16.9 0.0 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit TIR_2 PF13676.6 EGR31760.1 - 0.012 16.2 0.1 0.024 15.3 0.0 1.5 1 1 0 1 1 1 0 TIR domain TniB PF05621.11 EGR31760.1 - 0.014 14.8 0.0 0.036 13.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EGR31760.1 - 0.067 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TraG_N PF07916.11 EGR31761.1 - 0.0023 16.9 2.0 0.0023 16.9 2.0 2.4 2 1 0 2 2 2 1 TraG-like protein, N-terminal region DUF4207 PF13904.6 EGR31761.1 - 0.0029 17.3 1.8 0.0029 17.3 1.8 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4207) RTP1_C1 PF10363.9 EGR31761.1 - 0.029 14.5 0.1 0.029 14.5 0.1 4.3 2 1 1 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Ipi1_N PF12333.8 EGR31761.1 - 0.04 14.5 11.2 0.091 13.4 1.9 4.3 3 1 1 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation Shisa PF13908.6 EGR31761.1 - 0.44 10.8 2.1 0.9 9.7 2.1 1.6 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Exonuc_VII_L PF02601.15 EGR31762.1 - 0.0074 15.9 3.6 0.01 15.5 3.6 1.2 1 0 0 1 1 1 1 Exonuclease VII, large subunit LOH1CR12 PF10158.9 EGR31762.1 - 0.02 14.9 4.4 0.023 14.7 2.9 1.8 1 1 0 2 2 2 0 Tumour suppressor protein DUF745 PF05335.13 EGR31762.1 - 0.028 14.2 4.8 0.059 13.1 4.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF745) GAS PF13851.6 EGR31762.1 - 0.042 13.2 13.4 0.064 12.6 9.9 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DHR10 PF18595.1 EGR31762.1 - 0.069 13.2 13.2 0.082 13.0 4.9 2.2 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain MbeD_MobD PF04899.12 EGR31762.1 - 0.12 12.5 3.1 0.47 10.6 0.2 2.6 1 1 2 3 3 3 0 MbeD/MobD like ERM PF00769.19 EGR31762.1 - 0.19 11.5 11.3 0.34 10.7 11.3 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family KELK PF15796.5 EGR31762.1 - 0.21 12.1 11.5 0.47 10.9 6.4 3.0 2 1 1 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase KxDL PF10241.9 EGR31762.1 - 0.32 11.3 8.9 1.5 9.1 0.2 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein SlyX PF04102.12 EGR31762.1 - 0.43 11.2 8.8 0.65 10.7 0.6 3.3 1 1 3 4 4 4 0 SlyX DUF3450 PF11932.8 EGR31762.1 - 0.62 9.3 8.8 1.2 8.4 8.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Med4 PF10018.9 EGR31762.1 - 1.3 8.7 9.7 1.3 8.6 8.6 1.6 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 XhlA PF10779.9 EGR31762.1 - 1.3 9.3 12.4 3.5 7.9 3.4 3.0 2 1 1 3 3 3 0 Haemolysin XhlA DUF16 PF01519.16 EGR31762.1 - 5.7 7.5 12.1 2.8 8.5 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function DUF16 LMBR1 PF04791.16 EGR31762.1 - 6.9 5.4 5.3 8 5.2 5.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Swi5 PF07061.11 EGR31762.1 - 7.5 6.7 10.6 3.1 8.0 0.2 2.7 2 1 0 2 2 2 0 Swi5 TPR_1 PF00515.28 EGR31763.1 - 1.8e-34 116.1 33.8 3.6e-10 39.2 2.0 7.4 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGR31763.1 - 7.8e-34 113.1 21.3 1.3e-09 37.4 0.3 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGR31763.1 - 6.8e-24 82.0 25.7 1.1e-06 28.3 0.3 6.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 EGR31763.1 - 2.3e-22 78.4 32.2 3.3e-10 39.5 2.1 6.9 1 1 6 7 7 7 4 TPR repeat TPR_12 PF13424.6 EGR31763.1 - 1.5e-21 76.5 10.2 2.2e-09 37.4 0.1 5.4 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGR31763.1 - 6.8e-21 73.1 25.2 1.1e-07 31.8 0.3 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGR31763.1 - 7.4e-20 71.2 8.2 1.4e-06 28.7 0.7 5.1 1 1 3 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.6 EGR31763.1 - 8.5e-18 64.7 0.0 7.4e-06 26.5 0.1 5.0 2 1 2 5 5 5 4 Tetratricopeptide repeat TPR_6 PF13174.6 EGR31763.1 - 1.4e-17 63.0 3.1 0.019 15.6 0.0 6.1 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_7 PF13176.6 EGR31763.1 - 2.1e-17 61.8 6.8 0.00098 19.0 0.0 5.7 6 0 0 6 6 6 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR31763.1 - 1.6e-11 44.2 24.7 0.00038 20.6 3.0 4.3 2 1 4 6 6 6 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EGR31763.1 - 3.3e-09 36.8 0.0 0.087 13.7 0.0 5.9 1 1 6 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGR31763.1 - 3.6e-08 33.0 3.3 0.02 14.8 0.0 5.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 EGR31763.1 - 1e-07 32.2 0.6 0.17 12.2 0.2 3.8 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGR31763.1 - 4.2e-06 26.4 0.0 5.4e-05 22.7 0.0 2.1 1 1 1 2 2 2 1 MalT-like TPR region TPR_9 PF13371.6 EGR31763.1 - 0.0004 20.5 0.0 0.035 14.3 0.0 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Sel1 PF08238.12 EGR31763.1 - 0.0012 19.5 5.5 1.3 9.9 0.3 5.4 5 1 0 5 5 4 1 Sel1 repeat Fis1_TPR_C PF14853.6 EGR31763.1 - 0.002 18.2 20.5 0.0026 17.8 0.6 5.2 4 1 1 5 5 5 2 Fis1 C-terminal tetratricopeptide repeat TOM20_plant PF06552.12 EGR31763.1 - 0.0021 17.8 6.1 0.0034 17.2 0.9 3.2 3 1 1 4 4 4 2 Plant specific mitochondrial import receptor subunit TOM20 TPR_15 PF13429.6 EGR31763.1 - 0.035 13.3 0.6 2.8 7.1 0.0 2.8 1 1 0 2 2 2 0 Tetratricopeptide repeat SPO22 PF08631.10 EGR31763.1 - 0.14 11.6 3.8 0.43 10.0 1.3 2.4 1 1 1 2 2 2 0 Meiosis protein SPO22/ZIP4 like MIT PF04212.18 EGR31763.1 - 6.9 6.8 10.0 47 4.1 0.1 4.4 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 EGR31764.1 - 5.7e-89 288.6 101.7 2e-09 36.8 1.9 21.6 21 1 0 21 21 21 20 Tetratricopeptide repeat TPR_2 PF07719.17 EGR31764.1 - 8.2e-86 275.4 67.2 2.5e-07 30.3 0.6 21.8 21 0 0 21 21 21 18 Tetratricopeptide repeat TPR_8 PF13181.6 EGR31764.1 - 1.3e-67 218.4 90.3 2.1e-06 27.5 0.8 23.5 23 0 0 23 23 23 16 Tetratricopeptide repeat TPR_12 PF13424.6 EGR31764.1 - 1.3e-57 192.0 31.4 2.5e-08 34.1 0.6 14.0 8 5 7 15 15 15 13 Tetratricopeptide repeat TPR_19 PF14559.6 EGR31764.1 - 1.8e-54 182.1 30.4 4.2e-06 27.2 0.3 15.0 9 3 7 16 16 16 12 Tetratricopeptide repeat TPR_11 PF13414.6 EGR31764.1 - 3.9e-54 180.1 80.7 3e-08 33.2 0.1 18.4 12 4 8 20 20 20 15 TPR repeat TPR_17 PF13431.6 EGR31764.1 - 9.3e-53 172.9 66.6 6.2e-05 23.1 0.0 21.2 21 0 0 21 21 21 14 Tetratricopeptide repeat TPR_16 PF13432.6 EGR31764.1 - 2.8e-41 139.9 0.0 0.00041 20.9 0.0 13.3 11 2 3 14 14 14 8 Tetratricopeptide repeat TPR_6 PF13174.6 EGR31764.1 - 2.1e-39 131.6 40.1 0.0067 17.0 0.1 21.6 23 0 0 23 23 22 9 Tetratricopeptide repeat TPR_14 PF13428.6 EGR31764.1 - 1.3e-36 122.1 0.0 0.005 17.6 0.0 17.9 4 3 14 19 19 19 8 Tetratricopeptide repeat TPR_7 PF13176.6 EGR31764.1 - 1.2e-35 118.9 24.0 0.012 15.6 0.1 16.4 16 1 1 17 17 17 9 Tetratricopeptide repeat TPR_10 PF13374.6 EGR31764.1 - 2.8e-22 77.9 27.1 0.076 12.9 0.4 14.7 17 0 0 17 17 17 8 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR31764.1 - 3.2e-19 68.9 75.2 0.00057 20.0 0.6 12.8 8 4 6 14 14 12 8 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGR31764.1 - 6.2e-15 55.1 0.0 0.34 11.1 0.0 8.5 8 2 2 10 10 10 3 Tetratricopeptide repeat TPR_20 PF14561.6 EGR31764.1 - 4.4e-12 46.2 49.8 0.00016 22.0 0.0 13.5 12 2 5 17 17 14 5 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGR31764.1 - 0.00072 19.6 0.5 0.027 14.5 0.2 13.4 11 2 2 13 13 12 4 Fis1 C-terminal tetratricopeptide repeat Ribosomal_L11_N PF03946.14 EGR31765.1 - 3e-20 71.8 0.0 5.3e-20 71.0 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EGR31765.1 - 3.4e-11 43.5 0.0 9.1e-11 42.1 0.0 1.8 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain SpoIIE PF07228.12 EGR31765.1 - 8.5e-09 35.6 0.0 1.2e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) DUF4864 PF16156.5 EGR31765.1 - 0.12 13.1 0.0 0.33 11.7 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4864) ArabFuran-catal PF09206.11 EGR31766.1 - 0.0082 15.5 3.6 0.0082 15.5 3.6 1.9 2 0 0 2 2 2 1 Alpha-L-arabinofuranosidase B, catalytic Hid1 PF12722.7 EGR31766.1 - 0.19 9.8 37.2 0.24 9.5 37.2 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PI3K_1B_p101 PF10486.9 EGR31766.1 - 3.4 5.3 26.0 4.5 4.9 26.0 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Dapper PF15268.6 EGR31766.1 - 7 5.4 39.6 8.7 5.1 39.6 1.1 1 0 0 1 1 1 0 Dapper Nuc_sug_transp PF04142.15 EGR31767.1 - 7.8e-13 48.3 6.0 1.4e-12 47.5 5.5 1.6 2 0 0 2 2 2 1 Nucleotide-sugar transporter CRT-like PF08627.10 EGR31767.1 - 2.2e-08 33.5 11.4 2.2e-08 33.5 11.4 1.7 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like UAA PF08449.11 EGR31767.1 - 3.7e-07 29.7 13.8 5.4e-07 29.1 13.8 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGR31767.1 - 7e-05 23.0 8.8 7e-05 23.0 8.8 3.2 3 0 0 3 3 3 1 EamA-like transporter family TPT PF03151.16 EGR31767.1 - 0.88 8.9 15.9 0.012 15.0 4.0 2.5 2 1 0 2 2 2 0 Triose-phosphate Transporter family DUF4293 PF14126.6 EGR31767.1 - 3.8 7.8 14.7 0.59 10.4 7.8 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) TPR_1 PF00515.28 EGR31768.1 - 4.3e-87 282.7 77.5 2.7e-08 33.3 0.2 17.3 17 0 0 17 17 17 16 Tetratricopeptide repeat TPR_2 PF07719.17 EGR31768.1 - 1.8e-77 249.4 65.5 1.8e-07 30.7 0.1 17.9 18 0 0 18 18 18 15 Tetratricopeptide repeat TPR_11 PF13414.6 EGR31768.1 - 2.7e-63 209.4 66.1 5.9e-09 35.5 1.4 16.8 8 4 9 17 17 17 13 TPR repeat TPR_16 PF13432.6 EGR31768.1 - 2.2e-45 153.0 9.2 2.7e-05 24.7 0.1 10.0 8 3 2 10 10 10 8 Tetratricopeptide repeat TPR_8 PF13181.6 EGR31768.1 - 4.5e-38 126.3 60.2 1.8e-05 24.6 0.5 17.3 17 0 0 17 17 17 9 Tetratricopeptide repeat TPR_12 PF13424.6 EGR31768.1 - 6e-30 103.4 49.5 4.6e-06 26.8 0.6 11.7 7 3 6 13 13 13 8 Tetratricopeptide repeat TPR_17 PF13431.6 EGR31768.1 - 6e-29 98.3 47.3 5e-06 26.5 0.4 14.7 15 0 0 15 15 15 9 Tetratricopeptide repeat TPR_9 PF13371.6 EGR31768.1 - 1.4e-28 98.8 6.5 0.0057 16.8 0.0 11.1 4 3 7 11 11 11 9 Tetratricopeptide repeat TPR_14 PF13428.6 EGR31768.1 - 9.6e-22 75.8 5.1 0.15 13.0 0.0 13.2 8 4 7 15 15 14 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGR31768.1 - 7.4e-20 70.2 34.6 0.28 11.9 0.1 15.1 16 0 0 16 16 16 7 Tetratricopeptide repeat TPR_7 PF13176.6 EGR31768.1 - 2.1e-12 46.1 29.3 0.18 11.9 0.1 12.8 15 0 0 15 15 13 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGR31768.1 - 1.8e-11 44.4 40.2 0.0028 18.1 0.3 10.4 5 4 5 11 11 11 5 Tetratricopeptide repeat TPR_15 PF13429.6 EGR31768.1 - 2.9e-11 43.1 13.0 0.2 10.8 0.1 7.4 2 2 3 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR31768.1 - 1.7e-10 41.0 47.2 0.00048 20.3 0.6 8.5 2 2 7 9 9 9 7 Anaphase-promoting complex, cyclosome, subunit 3 MaoC_dehydratas PF01575.19 EGR31768.1 - 8.2e-08 31.9 0.0 1.6e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 MaoC like domain NARP1 PF12569.8 EGR31768.1 - 2.9e-05 23.2 29.4 0.46 9.3 0.0 7.1 4 1 2 7 7 6 4 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 EGR31768.1 - 0.00021 21.5 21.6 0.067 13.5 0.0 7.0 7 2 2 9 9 8 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGR31768.1 - 0.0017 18.1 39.1 0.0083 16.0 0.9 10.5 12 0 0 12 12 11 2 Tetratricopeptide repeat Sel1 PF08238.12 EGR31768.1 - 0.0083 16.8 8.8 6.4 7.6 0.1 5.3 5 0 0 5 5 4 1 Sel1 repeat MIT PF04212.18 EGR31768.1 - 0.031 14.3 47.2 0.58 10.3 1.1 10.6 8 4 3 11 11 11 0 MIT (microtubule interacting and transport) domain SDH_beta PF03315.15 EGR31768.1 - 0.046 14.1 2.8 5.7 7.3 0.0 3.1 3 0 0 3 3 3 0 Serine dehydratase beta chain MKT1_C PF12246.8 EGR31768.1 - 0.071 12.3 2.6 0.18 11.0 2.6 1.6 1 0 0 1 1 1 0 Temperature dependent protein affecting M2 dsRNA replication DUF357 PF04010.13 EGR31768.1 - 0.17 12.0 13.3 0.23 11.6 0.4 5.2 5 1 1 6 6 5 0 Protein of unknown function (DUF357) PknG_TPR PF16918.5 EGR31768.1 - 0.18 10.5 0.3 8.1 5.1 0.0 3.3 5 0 0 5 5 5 0 Protein kinase G tetratricopeptide repeat BTAD PF03704.17 EGR31768.1 - 0.4 11.1 6.9 40 4.6 0.0 4.5 3 3 1 4 4 4 0 Bacterial transcriptional activator domain DUF627 PF04781.12 EGR31768.1 - 1.3 9.0 9.9 10 6.2 0.1 5.2 5 1 1 6 6 5 0 Protein of unknown function (DUF627) HTH_Bact PF18768.1 EGR31768.1 - 2.1 8.0 13.0 2.3 7.9 0.0 5.7 6 0 0 6 6 5 0 Helix-turn-helix bacterial domain TPR_1 PF00515.28 EGR31769.1 - 6.9e-59 193.4 57.3 4.3e-09 35.8 1.0 10.2 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 EGR31769.1 - 5e-54 176.1 37.1 2.4e-06 27.2 0.4 10.0 10 0 0 10 10 9 9 Tetratricopeptide repeat TPR_11 PF13414.6 EGR31769.1 - 1.1e-42 143.4 36.5 7.5e-08 31.9 1.8 9.9 6 2 3 9 9 9 9 TPR repeat TPR_8 PF13181.6 EGR31769.1 - 8.4e-37 122.3 42.0 4e-06 26.6 0.4 10.1 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_16 PF13432.6 EGR31769.1 - 2e-28 98.7 0.0 2.5e-05 24.8 0.0 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGR31769.1 - 1.3e-24 84.8 0.0 0.0053 17.5 0.0 9.2 5 3 4 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 EGR31769.1 - 3.6e-23 81.6 14.0 2.1e-06 27.9 0.1 7.8 5 2 2 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 EGR31769.1 - 2.3e-22 77.7 32.4 3.2e-05 24.0 0.3 10.9 12 0 0 12 12 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 EGR31769.1 - 6.8e-22 77.8 11.1 9.1e-05 22.9 0.3 7.7 4 3 3 7 7 7 5 Tetratricopeptide repeat STI1 PF17830.1 EGR31769.1 - 7.2e-20 70.7 31.7 5.9e-12 45.3 14.2 3.5 3 1 0 3 3 3 2 STI1 domain TPR_9 PF13371.6 EGR31769.1 - 4.6e-19 68.3 0.0 0.00015 21.8 0.0 5.8 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGR31769.1 - 6.6e-17 60.2 13.5 0.046 13.8 0.2 10.1 9 1 0 10 10 10 4 Tetratricopeptide repeat TPR_10 PF13374.6 EGR31769.1 - 3.5e-10 39.4 15.6 1.4 8.9 0.1 9.9 10 1 1 11 11 11 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR31769.1 - 9.4e-10 38.6 23.2 0.00048 20.3 1.3 5.4 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGR31769.1 - 2.3e-09 37.3 20.2 0.35 11.6 0.0 9.9 10 0 0 10 10 10 2 Tetratricopeptide repeat NARP1 PF12569.8 EGR31769.1 - 0.00038 19.5 4.9 0.0037 16.2 0.5 6.3 1 1 5 6 6 5 3 NMDA receptor-regulated protein 1 ChAPs PF09295.10 EGR31769.1 - 0.00048 19.2 6.0 0.041 12.9 0.7 3.4 2 1 1 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.6 EGR31769.1 - 0.00079 19.4 16.2 1.8 8.7 0.1 7.5 7 1 1 8 8 7 1 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 EGR31769.1 - 0.0011 19.4 1.9 11 6.5 0.0 4.5 2 2 2 4 4 4 0 Bacterial transcriptional activator domain MIT PF04212.18 EGR31769.1 - 0.0027 17.7 32.3 1.8 8.7 1.0 8.2 6 2 1 7 7 7 2 MIT (microtubule interacting and transport) domain DUF2052 PF09747.9 EGR31769.1 - 0.0075 16.4 12.8 0.0075 16.4 12.8 3.0 3 0 0 3 3 3 1 Coiled-coil domain containing protein (DUF2052) SHNi-TPR PF10516.9 EGR31769.1 - 0.013 14.9 12.4 11 5.6 0.0 6.7 8 0 0 8 8 6 0 SHNi-TPR PPR PF01535.20 EGR31769.1 - 0.025 14.8 9.1 49 4.5 0.1 7.2 8 0 0 8 8 8 0 PPR repeat Glyco_transf_8C PF08437.10 EGR31769.1 - 0.036 14.2 1.5 0.18 11.9 0.2 3.0 2 0 0 2 2 2 0 Glycosyl transferase family 8 C-terminal DUF5113 PF17140.4 EGR31769.1 - 0.049 13.5 19.8 0.093 12.5 0.4 5.1 5 2 0 5 5 5 0 Domain of unknown function (DUF5113) TPR_20 PF14561.6 EGR31769.1 - 0.091 13.1 0.1 0.091 13.1 0.1 5.7 4 1 0 5 5 4 0 Tetratricopeptide repeat UPF0524 PF15823.5 EGR31769.1 - 0.12 11.8 5.6 0.33 10.3 5.7 1.7 2 0 0 2 2 2 0 UPF0524 of C3orf70 Zip PF02535.22 EGR31769.1 - 4.7 6.3 5.1 6.8 5.8 5.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Folliculin PF11704.8 EGR31769.1 - 5.7 6.8 8.7 18 5.2 8.7 1.8 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Glyco_hydro_31 PF01055.26 EGR31770.1 - 1.4e-116 390.3 10.1 1.9e-116 389.9 10.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EGR31770.1 - 2.1e-12 47.1 2.1 5e-11 42.8 0.1 3.0 3 0 0 3 3 3 1 Galactose mutarotase-like MORN PF02493.20 EGR31771.1 - 7e-53 173.5 83.5 9.3e-07 28.4 0.7 10.0 10 0 0 10 10 10 9 MORN repeat Tudor_2 PF18104.1 EGR31771.1 - 0.22 11.2 19.8 2.2 8.0 0.3 5.8 5 0 0 5 5 5 0 Jumonji domain-containing protein 2A Tudor domain DUF1419 PF07215.11 EGR31771.1 - 1.9 8.6 7.7 3.6 7.7 0.1 4.2 3 2 1 5 5 5 0 Protein of unknown function (DUF1419) ID PF18543.1 EGR31771.1 - 5.5 7.1 12.6 4.7 7.3 0.0 4.6 6 0 0 6 6 6 0 Intracellular delivery domain Peptidase_M41 PF01434.18 EGR31772.1 - 7.7e-53 179.2 0.3 1.6e-52 178.2 0.3 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EGR31772.1 - 5.8e-28 97.9 0.1 1.8e-27 96.3 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGR31772.1 - 1.3e-09 37.7 0.0 3.3e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EGR31772.1 - 0.04 14.0 0.7 0.17 12.0 0.1 2.3 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) Peptidase_M50B PF13398.6 EGR31772.1 - 0.13 11.9 0.2 0.19 11.3 0.2 1.2 1 0 0 1 1 1 0 Peptidase M50B-like SWIRM PF04433.17 EGR31774.1 - 6.1e-28 97.0 0.7 6.1e-28 97.0 0.7 4.5 3 1 1 4 4 4 1 SWIRM domain Molybdop_Fe4S4 PF04879.16 EGR31774.1 - 0.017 15.1 1.7 0.097 12.7 0.0 2.8 3 0 0 3 3 3 0 Molybdopterin oxidoreductase Fe4S4 domain FPN1 PF06963.12 EGR31774.1 - 3.4 6.1 4.5 7.1 5.1 4.5 1.5 1 0 0 1 1 1 0 Ferroportin1 (FPN1) SIMPL PF04402.14 EGR31775.1 - 8.4e-20 72.1 4.1 9.6e-20 71.9 4.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) EF-hand_7 PF13499.6 EGR31776.1 - 1.2e-09 38.5 12.8 6.1e-08 33.0 2.8 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR31776.1 - 3.9e-07 29.5 8.1 0.0059 16.5 0.3 4.0 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 EGR31776.1 - 2e-06 26.9 12.0 0.021 14.4 0.3 4.4 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EGR31776.1 - 6.3e-05 22.7 10.2 0.0049 16.7 2.4 3.7 3 1 1 4 4 4 3 EF-hand domain pair WD40 PF00400.32 EGR31777.1 - 6.8e-07 29.9 0.2 0.12 13.3 0.1 5.5 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR31777.1 - 0.051 13.9 0.2 14 6.1 0.0 4.6 4 2 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Ax_dynein_light PF10211.9 EGR31778.1 - 1.3e-45 155.6 4.8 1.6e-45 155.4 4.8 1.0 1 0 0 1 1 1 1 Axonemal dynein light chain Kinesin PF00225.23 EGR31783.1 - 1.2e-88 297.3 4.6 1.5e-88 296.9 4.6 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR31783.1 - 5.8e-34 117.2 0.8 5.8e-34 117.2 0.8 1.7 2 0 0 2 2 2 1 Microtubule binding ABC1 PF03109.16 EGR31784.1 - 3.6e-28 98.1 0.1 6.8e-28 97.2 0.1 1.4 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 EGR31784.1 - 0.0015 18.1 0.0 0.0038 16.9 0.0 1.7 1 0 0 1 1 1 1 RIO1 family Pkinase PF00069.25 EGR31784.1 - 0.0078 15.6 2.1 0.033 13.6 0.6 2.5 2 1 0 2 2 2 1 Protein kinase domain APG5 PF04106.12 EGR31784.1 - 0.073 12.7 0.6 0.26 10.8 0.1 1.9 2 0 0 2 2 2 0 Autophagy protein Apg5 APH PF01636.23 EGR31784.1 - 0.12 12.3 0.1 0.23 11.3 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family IKKbetaNEMObind PF12179.8 EGR31785.1 - 0.12 12.4 2.3 2.2 8.4 0.2 3.6 3 0 0 3 3 3 0 I-kappa-kinase-beta NEMO binding domain Dabb PF07876.12 EGR31785.1 - 3.6 8.3 9.2 0.63 10.7 0.5 3.5 3 1 0 3 3 3 0 Stress responsive A/B Barrel Domain Lon_C PF05362.13 EGR31786.1 - 3.2e-73 245.6 0.6 9.7e-73 244.1 0.6 1.9 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 EGR31786.1 - 4.3e-24 85.4 0.0 2.4e-23 83.0 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 EGR31786.1 - 2.3e-13 50.5 9.0 2.3e-13 50.5 9.0 2.6 1 1 1 2 2 2 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 EGR31786.1 - 7.5e-10 38.7 0.5 4.9e-09 36.1 0.2 2.6 2 1 0 2 2 2 1 Subunit ChlI of Mg-chelatase AAA_5 PF07728.14 EGR31786.1 - 1.9e-09 37.6 0.0 5.4e-09 36.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGR31786.1 - 4.4e-07 30.2 0.1 2.5e-06 27.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGR31786.1 - 1.9e-06 28.4 1.4 0.0036 17.7 0.1 3.2 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGR31786.1 - 2.5e-05 24.6 2.3 0.0018 18.6 0.2 3.4 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGR31786.1 - 0.00013 22.5 1.2 0.00077 20.0 0.1 2.8 2 0 0 2 2 2 1 AAA domain RuvB_N PF05496.12 EGR31786.1 - 0.00016 21.5 0.0 0.0045 16.7 0.0 3.2 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EGR31786.1 - 0.0016 18.2 0.0 0.0042 16.9 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_3 PF07726.11 EGR31786.1 - 0.0017 18.2 0.0 0.012 15.4 0.0 2.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EGR31786.1 - 0.0036 17.2 0.1 0.54 10.2 0.0 3.3 1 1 1 2 2 2 1 NTPase RNA_helicase PF00910.22 EGR31786.1 - 0.0062 16.9 0.4 0.041 14.3 0.0 2.7 3 0 0 3 3 2 1 RNA helicase RsgA_GTPase PF03193.16 EGR31786.1 - 0.0092 15.9 0.4 0.082 12.8 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase AAA_14 PF13173.6 EGR31786.1 - 0.032 14.2 0.0 0.032 14.2 0.0 3.3 3 1 0 3 3 2 0 AAA domain AAA_33 PF13671.6 EGR31786.1 - 0.038 14.2 0.0 0.11 12.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EGR31786.1 - 0.065 12.4 0.0 0.065 12.4 0.0 2.7 3 0 0 3 3 3 0 NB-ARC domain TsaE PF02367.17 EGR31786.1 - 0.08 12.9 0.0 0.21 11.6 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 EGR31786.1 - 0.56 10.7 8.4 0.64 10.5 0.0 3.3 3 0 0 3 3 3 0 ABC transporter zf-CCCH_6 PF18585.1 EGR31786.1 - 0.66 9.9 4.3 0.28 11.1 0.3 2.5 3 0 0 3 3 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Peptidase_M8 PF01457.16 EGR31787.1 - 1.3e-41 142.9 6.7 3.1e-38 131.8 0.0 2.6 2 1 1 3 3 3 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR31787.1 - 2.1e-05 24.4 5.0 0.00016 21.7 5.0 2.6 1 0 0 1 1 1 1 Tenascin EGF domain EGF_2 PF07974.13 EGR31787.1 - 0.00065 20.0 13.1 0.00065 20.0 13.1 7.1 6 2 1 7 7 7 1 EGF-like domain RSS_P20 PF11757.8 EGR31787.1 - 0.025 15.0 1.3 0.1 13.1 0.1 2.8 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain CK_II_beta PF01214.18 EGR31788.1 - 5.8e-49 166.4 0.9 1.3e-48 165.3 0.0 1.7 2 0 0 2 2 2 1 Casein kinase II regulatory subunit TPR_1 PF00515.28 EGR31789.1 - 6.1e-39 130.3 32.0 7.3e-08 31.9 1.6 8.2 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 EGR31789.1 - 2.7e-34 114.5 24.3 1.1e-06 28.3 0.3 9.0 9 0 0 9 9 8 6 Tetratricopeptide repeat DnaJ PF00226.31 EGR31789.1 - 9.9e-26 89.7 1.3 9.9e-26 89.7 1.3 2.7 2 0 0 2 2 2 1 DnaJ domain TPR_19 PF14559.6 EGR31789.1 - 3.3e-20 72.4 18.7 0.0026 18.2 0.1 7.1 2 2 4 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 EGR31789.1 - 1.8e-19 69.1 18.0 3.9e-05 23.2 0.5 6.6 4 2 2 6 6 6 4 TPR repeat TPR_8 PF13181.6 EGR31789.1 - 6.8e-14 50.9 27.7 9.3e-05 22.4 0.0 8.6 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGR31789.1 - 4e-13 49.0 0.0 0.055 14.3 0.0 5.9 3 1 3 6 6 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGR31789.1 - 3e-11 43.8 0.0 0.055 14.1 0.0 4.3 3 1 0 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.6 EGR31789.1 - 7.6e-11 42.0 2.2 0.00034 20.7 0.0 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGR31789.1 - 7.8e-11 42.1 7.0 0.033 14.5 0.1 5.9 4 2 2 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGR31789.1 - 2e-08 34.0 19.7 0.19 12.2 0.3 7.5 8 1 0 8 8 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGR31789.1 - 1.1e-07 31.4 2.1 0.32 11.1 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGR31789.1 - 7e-06 26.4 11.4 0.47 11.2 0.0 7.9 8 2 1 9 9 8 2 Tetratricopeptide repeat RPT PF13446.6 EGR31789.1 - 0.0003 20.6 0.8 0.0069 16.3 0.0 3.6 3 1 1 4 4 4 1 A repeated domain in UCH-protein PknG_TPR PF16918.5 EGR31789.1 - 0.0035 16.1 0.1 0.014 14.2 0.0 1.9 1 1 1 2 2 2 1 Protein kinase G tetratricopeptide repeat SRP_TPR_like PF17004.5 EGR31789.1 - 0.008 16.2 16.8 1 9.4 0.4 4.5 3 2 1 4 4 4 3 Putative TPR-like repeat Fis1_TPR_C PF14853.6 EGR31789.1 - 0.14 12.3 0.1 0.14 12.3 0.1 6.6 7 0 0 7 7 7 0 Fis1 C-terminal tetratricopeptide repeat TOM20_plant PF06552.12 EGR31789.1 - 0.49 10.1 9.2 0.66 9.7 0.1 3.8 2 2 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 Glyco_transf_8C PF08437.10 EGR31789.1 - 2.3 8.4 10.7 28 4.9 0.1 4.9 5 0 0 5 5 5 0 Glycosyl transferase family 8 C-terminal DUF5113 PF17140.4 EGR31789.1 - 2.4 7.9 15.5 0.2 11.5 3.3 4.0 2 2 2 4 4 4 0 Domain of unknown function (DUF5113) MIT PF04212.18 EGR31789.1 - 7.8 6.7 26.7 4 7.6 0.7 6.0 6 1 1 7 7 5 0 MIT (microtubule interacting and transport) domain GIDA PF01134.22 EGR31790.1 - 2.4e-135 451.6 9.0 2.4e-135 451.6 9.0 2.4 2 2 0 2 2 2 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EGR31790.1 - 1.6e-54 185.3 4.8 1.6e-54 185.3 4.8 2.2 2 1 0 2 2 2 1 GidA associated domain Pyr_redox_2 PF07992.14 EGR31790.1 - 0.00054 19.3 3.5 0.0022 17.3 3.5 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGR31790.1 - 0.0015 17.9 2.1 0.17 11.1 0.1 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGR31790.1 - 0.025 13.7 0.1 0.13 11.3 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain DUF4755 PF15947.5 EGR31790.1 - 0.034 14.1 0.8 0.11 12.4 0.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4755) FAD_oxidored PF12831.7 EGR31790.1 - 0.19 11.1 1.2 0.67 9.2 1.2 2.0 1 1 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EGR31790.1 - 2.1 6.9 8.8 5.9 5.5 0.0 4.0 4 1 0 4 4 4 0 HI0933-like protein Folliculin PF11704.8 EGR31791.1 - 0.9 9.4 8.5 7.2 6.5 3.8 2.6 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport HXXSHH PF07586.11 EGR31792.1 - 0.0013 18.4 9.7 0.0013 18.3 9.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1552) NADPH_Ox PF08414.10 EGR31792.1 - 0.017 15.4 0.6 0.017 15.4 0.6 1.7 1 1 1 2 2 2 0 Respiratory burst NADPH oxidase AFOR_C PF01314.18 EGR31792.1 - 0.042 12.9 0.0 0.049 12.6 0.0 1.1 1 0 0 1 1 1 0 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 DUF445 PF04286.12 EGR31792.1 - 0.099 12.4 11.9 0.11 12.3 11.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) Pex14_N PF04695.13 EGR31792.1 - 0.21 12.2 13.3 0.26 11.9 13.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RR_TM4-6 PF06459.12 EGR31792.1 - 0.22 11.3 11.6 0.25 11.1 11.6 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FUSC PF04632.12 EGR31792.1 - 0.24 9.9 7.0 0.26 9.8 7.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family TFIIA PF03153.13 EGR31792.1 - 0.81 9.6 28.6 0.93 9.4 28.6 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Het-C PF07217.11 EGR31792.1 - 1.5 7.3 13.2 2.1 6.8 13.2 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C DDHD PF02862.17 EGR31792.1 - 3 7.9 10.5 3.6 7.7 10.5 1.1 1 0 0 1 1 1 0 DDHD domain APG6_N PF17675.1 EGR31792.1 - 4.4 7.8 26.5 3.3 8.2 24.8 1.6 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4407 PF14362.6 EGR31792.1 - 4.7 6.5 18.7 5.7 6.2 18.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FtsX_ECD PF18075.1 EGR31792.1 - 5.1 7.8 16.2 1.2 9.8 10.2 2.3 1 1 1 2 2 2 0 FtsX extracellular domain Hid1 PF12722.7 EGR31792.1 - 6.4 4.8 14.2 7.6 4.5 14.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein V_ATPase_I PF01496.19 EGR31792.1 - 9.7 4.0 15.1 11 3.8 15.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SHIPPO-rpt PF07004.12 EGR31794.1 - 8.8e-12 45.4 33.6 0.87 10.6 0.4 10.1 10 0 0 10 10 10 8 Sperm-tail PG-rich repeat Ribosomal_S3_C PF00189.20 EGR31795.1 - 4.7e-21 75.1 0.5 1.2e-20 73.8 0.5 1.7 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain SHIPPO-rpt PF07004.12 EGR31795.1 - 3e-10 40.5 65.1 0.0017 19.2 1.2 11.4 11 0 0 11 11 11 7 Sperm-tail PG-rich repeat KH_2 PF07650.17 EGR31795.1 - 2.5e-07 30.4 0.0 8.8e-07 28.7 0.0 2.0 1 0 0 1 1 1 1 KH domain Hydrolase_4 PF12146.8 EGR31796.1 - 7.4e-11 41.8 0.0 2.5e-08 33.5 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR31796.1 - 1.2e-07 31.6 0.2 5e-07 29.6 0.0 2.0 2 1 1 3 3 3 1 alpha/beta hydrolase fold MCM PF00493.23 EGR31798.1 - 3.6e-96 320.6 0.4 5.4e-96 320.0 0.4 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGR31798.1 - 6.8e-35 119.7 0.9 1.3e-34 118.7 0.9 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGR31798.1 - 8.9e-30 103.0 2.1 2.5e-29 101.5 2.1 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGR31798.1 - 4.9e-09 36.7 0.5 2.3e-08 34.6 0.5 2.2 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGR31798.1 - 3e-06 26.8 0.0 7.1e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGR31798.1 - 0.00012 21.9 0.0 0.00036 20.4 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGR31798.1 - 0.0059 16.6 0.1 0.5 10.4 0.0 2.8 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EGR31798.1 - 0.013 15.2 0.1 0.033 13.9 0.1 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 EGR31798.1 - 0.43 11.2 3.6 0.19 12.4 0.3 2.2 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal MFS_1 PF07690.16 EGR31799.1 - 4.8e-29 101.4 31.5 3.1e-16 59.2 3.9 3.0 2 1 1 3 3 3 3 Major Facilitator Superfamily Sugar_tr PF00083.24 EGR31799.1 - 1.8e-06 27.1 36.9 1.9e-06 27.0 3.7 3.3 2 2 1 3 3 3 3 Sugar (and other) transporter MFS_3 PF05977.13 EGR31799.1 - 0.24 9.8 8.0 0.3 9.4 0.2 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector LIDHydrolase PF10230.9 EGR31800.1 - 1.3e-46 159.3 3.6 1.7e-46 159.0 3.6 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 EGR31800.1 - 1.5e-05 24.4 0.0 2.1e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF3910 PF13049.6 EGR31800.1 - 0.0092 16.3 1.1 0.027 14.8 1.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3910) Lipase_3 PF01764.25 EGR31800.1 - 0.059 13.2 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Hydrolase_3 PF08282.12 EGR31800.1 - 1.4 8.6 5.8 0.34 10.6 1.1 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase Pkinase PF00069.25 EGR31801.1 - 1.8e-48 165.2 3.8 1.1e-46 159.3 3.8 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31801.1 - 4.1e-33 114.8 0.3 5.7e-32 111.0 0.3 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR31801.1 - 1.9e-06 26.9 0.1 2.8e-06 26.4 0.1 1.3 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGR31801.1 - 0.00024 20.2 11.8 0.00031 19.8 11.8 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EGR31801.1 - 0.00092 18.4 1.8 0.0089 15.1 0.2 2.3 1 1 1 2 2 2 1 Seadornavirus VP7 Kinase-like PF14531.6 EGR31801.1 - 0.0046 16.3 0.2 0.0046 16.3 0.2 3.1 2 2 1 3 3 3 1 Kinase-like NUDIX PF00293.28 EGR31803.1 - 6.5e-06 26.2 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Pkinase PF00069.25 EGR31805.1 - 1.9e-46 158.6 0.3 2.1e-46 158.4 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31805.1 - 1.2e-28 100.1 0.0 1.5e-28 99.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31805.1 - 4.1e-11 42.7 0.0 6.7e-11 42.0 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR31805.1 - 2.1e-06 26.8 0.2 2.5e-06 26.5 0.2 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR31805.1 - 0.0065 15.8 0.2 0.01 15.2 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGR31805.1 - 0.025 14.2 0.5 0.037 13.6 0.5 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EGR31805.1 - 0.03 14.2 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 EGR31806.1 - 6.4e-53 179.8 4.0 1e-51 175.9 4.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31806.1 - 2.8e-25 89.1 0.5 3.6e-25 88.7 0.5 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR31806.1 - 3.4e-06 27.2 0.0 5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR31806.1 - 4.6e-05 22.9 0.6 8.3e-05 22.0 0.6 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR31806.1 - 0.00026 19.9 0.0 0.00038 19.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGR31806.1 - 0.00075 18.9 0.7 0.0012 18.3 0.7 1.3 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EGR31806.1 - 0.0022 17.7 4.5 0.0047 16.6 0.5 2.5 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 VWA_CoxE PF05762.14 EGR31807.1 - 2.3e-05 23.9 0.0 6.2e-05 22.5 0.0 1.5 1 1 0 1 1 1 1 VWA domain containing CoxE-like protein vWA-TerF-like PF10138.9 EGR31807.1 - 0.00094 19.3 0.2 0.0058 16.8 0.0 2.3 1 1 1 2 2 2 1 vWA found in TerF C terminus DUF2877 PF11392.8 EGR31808.1 - 2.3 9.0 6.3 1.6 9.4 5.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2877) zf-RING_2 PF13639.6 EGR31809.1 - 1.8e-13 50.6 6.9 2.8e-13 50.0 6.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGR31809.1 - 2.2e-10 40.6 7.0 5e-10 39.5 7.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EGR31809.1 - 4.9e-09 35.8 6.0 4.9e-09 35.8 6.0 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGR31809.1 - 1.2e-08 34.6 6.9 2.2e-08 33.8 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGR31809.1 - 1.4e-07 31.3 7.5 2.5e-07 30.4 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGR31809.1 - 3e-07 30.3 7.1 5.1e-07 29.5 7.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGR31809.1 - 8.7e-07 28.7 4.8 1.5e-06 27.9 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGR31809.1 - 9.4e-06 25.6 1.3 9.4e-06 25.6 1.3 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGR31809.1 - 0.00018 21.5 5.4 0.0011 19.0 5.4 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGR31809.1 - 0.00095 18.7 6.6 0.0015 18.1 6.6 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EGR31809.1 - 0.0013 18.5 6.2 0.0024 17.7 6.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Nse PF11789.8 EGR31809.1 - 0.0026 17.5 4.2 0.0044 16.8 4.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-HC5HC2H PF13771.6 EGR31809.1 - 0.0053 17.0 2.8 0.0053 17.0 2.8 2.1 1 1 1 2 2 2 1 PHD-like zinc-binding domain Prok-RING_1 PF14446.6 EGR31809.1 - 0.019 14.9 7.3 0.28 11.2 2.0 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-HC5HC2H_2 PF13832.6 EGR31809.1 - 0.023 14.9 5.6 0.023 14.9 5.6 1.8 1 1 1 2 2 2 0 PHD-zinc-finger like domain zf-RING-like PF08746.11 EGR31809.1 - 0.027 14.8 6.9 0.046 14.0 6.9 1.4 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 EGR31809.1 - 0.045 13.5 5.3 0.091 12.6 5.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3H2C3 PF17122.5 EGR31809.1 - 0.1 12.6 6.2 0.26 11.3 6.2 1.8 1 1 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 EGR31809.1 - 0.14 12.4 9.1 1.4 9.1 9.1 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 EGR31809.1 - 0.29 11.3 7.9 2.5 8.3 8.1 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.7 EGR31809.1 - 0.52 10.5 8.1 1.9 8.6 8.1 1.9 1 1 0 1 1 1 0 RING-variant domain PHD PF00628.29 EGR31809.1 - 2 8.4 9.0 1.3 9.0 6.9 1.8 2 0 0 2 2 2 0 PHD-finger Sortilin-Vps10 PF15902.5 EGR31810.1 - 1.2e-90 304.5 6.8 2e-90 303.7 6.2 1.7 1 1 1 2 2 2 2 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EGR31810.1 - 9e-37 127.0 13.4 2e-36 125.9 13.4 1.6 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal PSII_BNR PF14870.6 EGR31810.1 - 4.4e-06 26.2 1.8 0.022 14.0 0.0 3.9 2 2 2 4 4 4 2 Photosynthesis system II assembly factor YCF48 BNR_2 PF13088.6 EGR31810.1 - 0.0029 17.0 0.1 0.18 11.1 0.0 3.1 3 1 0 3 3 3 1 BNR repeat-like domain BNR PF02012.20 EGR31810.1 - 0.0041 16.9 23.0 0.39 10.9 0.0 7.0 8 0 0 8 8 8 3 BNR/Asp-box repeat WD40 PF00400.32 EGR31811.1 - 3.9e-11 43.3 3.8 0.043 14.7 0.0 7.3 8 1 0 8 8 8 2 WD domain, G-beta repeat HELP PF03451.14 EGR31811.1 - 0.00013 21.8 0.0 0.00032 20.5 0.0 1.7 1 0 0 1 1 1 1 HELP motif ANAPC4_WD40 PF12894.7 EGR31811.1 - 0.00026 21.2 0.0 0.21 11.9 0.0 4.7 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PhoLip_ATPase_C PF16212.5 EGR31812.1 - 1.8e-68 231.0 33.5 1.8e-68 231.0 33.5 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGR31812.1 - 7.7e-17 60.7 5.6 7.7e-17 60.7 5.6 3.5 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGR31812.1 - 3.2e-14 53.7 0.2 6.2e-06 26.6 0.1 3.3 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGR31812.1 - 4.9e-10 39.2 0.0 2.9e-09 36.7 0.0 2.4 1 1 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGR31812.1 - 6.8e-08 32.5 0.0 3.2e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) DUF4488 PF14869.6 EGR31812.1 - 0.0022 17.9 3.9 0.0032 17.4 1.9 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4488) TraD_N PF12615.8 EGR31813.1 - 0.00087 20.0 4.1 0.00087 20.0 4.1 2.2 2 0 0 2 2 2 1 F sex factor protein N terminal DUF4378 PF14309.6 EGR31813.1 - 0.037 14.4 0.2 0.057 13.8 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4378) PhoLip_ATPase_C PF16212.5 EGR31814.1 - 3.3e-60 203.9 37.9 3.3e-60 203.9 37.9 3.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGR31814.1 - 1.8e-22 78.8 3.8 1.8e-22 78.8 3.8 3.4 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 EGR31814.1 - 1.5e-13 51.5 0.0 8.1e-07 29.5 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGR31814.1 - 3.4e-12 46.3 0.8 7.1e-11 42.0 0.1 3.3 2 1 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGR31814.1 - 3.6e-06 26.9 2.6 3.6e-06 26.9 2.6 4.6 3 1 3 6 6 6 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGR31814.1 - 7.8e-06 25.5 1.1 2.3e-05 24.0 0.0 2.4 3 0 0 3 3 3 1 E1-E2 ATPase Methyltransf_12 PF08242.12 EGR31814.1 - 0.24 12.2 3.5 2 9.2 0.1 3.5 3 0 0 3 3 3 0 Methyltransferase domain COPIIcoated_ERV PF07970.12 EGR31815.1 - 2.3e-38 132.3 2.9 3.1e-38 131.8 2.9 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGR31815.1 - 2.4e-29 101.5 0.4 2.4e-29 101.5 0.4 2.0 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Rad17 PF03215.15 EGR31815.1 - 0.025 14.5 0.0 0.051 13.5 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain Metallophos PF00149.28 EGR31816.1 - 3.6e-34 119.0 0.1 8.9e-34 117.8 0.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 EGR31816.1 - 0.047 14.0 0.7 0.11 12.8 0.1 1.9 2 0 0 2 2 2 0 PPP5 TPR repeat region DivIC PF04977.15 EGR31816.1 - 4.9 7.0 6.9 11 5.8 6.9 1.6 1 0 0 1 1 1 0 Septum formation initiator Pro_dh PF01619.18 EGR31817.1 - 3.6e-56 190.9 5.5 2.5e-54 184.8 5.5 2.1 1 1 0 1 1 1 1 Proline dehydrogenase FERM_M PF00373.18 EGR31817.1 - 0.3 11.5 7.5 1.4 9.4 7.5 2.2 1 1 0 1 1 1 0 FERM central domain SPARC_Ca_bdg PF10591.9 EGR31817.1 - 3.2 8.1 8.2 0.45 10.9 2.6 2.4 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region POTRA_2 PF08479.11 EGR31817.1 - 7 6.6 11.2 1.6 8.6 0.3 3.4 2 1 1 3 3 3 0 POTRA domain, ShlB-type Ribosomal_L18A PF01775.17 EGR31820.1 - 1.5e-40 138.1 2.7 1.5e-40 138.1 2.7 1.6 2 0 0 2 2 2 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Pkinase PF00069.25 EGR31821.1 - 1.9e-36 125.8 19.1 2.6e-24 86.0 12.5 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31821.1 - 1.3e-28 100.0 6.5 7.3e-22 77.9 3.5 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR31821.1 - 3.1e-05 22.9 8.2 6.7e-05 21.8 8.2 1.6 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EGR31821.1 - 0.0019 17.8 0.3 0.0019 17.8 0.3 2.4 2 0 0 2 2 2 1 RIO1 family Nucleoplasmin PF03066.15 EGR31821.1 - 0.15 12.6 3.3 0.37 11.3 0.6 2.8 2 0 0 2 2 2 0 Nucleoplasmin/nucleophosmin domain AAA PF00004.29 EGR31822.1 - 1.6e-13 51.2 0.2 3.5e-13 50.1 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGR31822.1 - 9.8e-11 41.8 0.0 1.6e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGR31822.1 - 1.4e-09 38.6 0.6 1.3e-08 35.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGR31822.1 - 6e-08 33.1 0.0 2e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 AAA domain Rad17 PF03215.15 EGR31822.1 - 8.5e-08 32.3 1.4 6.6e-07 29.4 1.4 2.3 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_14 PF13173.6 EGR31822.1 - 1.4e-06 28.4 0.5 2.3e-06 27.7 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 EGR31822.1 - 1.4e-06 28.5 0.0 2.4e-06 27.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGR31822.1 - 3.7e-06 27.4 0.2 5.2e-05 23.7 0.0 2.3 2 1 1 3 3 2 1 AAA ATPase domain AAA_30 PF13604.6 EGR31822.1 - 4.7e-06 26.5 0.0 7.1e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGR31822.1 - 5.3e-06 26.3 0.0 8.8e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EGR31822.1 - 1.6e-05 24.9 0.3 0.0061 16.5 0.0 2.3 1 1 1 2 2 2 1 NTPase ABC_tran PF00005.27 EGR31822.1 - 3.8e-05 24.2 1.5 4e-05 24.1 0.4 1.6 2 1 0 2 2 1 1 ABC transporter AAA_28 PF13521.6 EGR31822.1 - 4.1e-05 23.9 0.0 8.5e-05 22.8 0.0 1.6 2 0 0 2 2 1 1 AAA domain TsaE PF02367.17 EGR31822.1 - 5.3e-05 23.2 0.0 0.00012 22.0 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EGR31822.1 - 8e-05 22.4 0.1 0.00023 21.0 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein DnaB_C PF03796.15 EGR31822.1 - 9e-05 21.9 0.0 0.00013 21.3 0.0 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain Zeta_toxin PF06414.12 EGR31822.1 - 0.00012 21.5 0.0 0.00021 20.6 0.0 1.5 1 1 0 1 1 1 1 Zeta toxin TIP49 PF06068.13 EGR31822.1 - 0.00012 21.4 0.0 0.00017 20.9 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_17 PF13207.6 EGR31822.1 - 0.00013 22.4 1.5 0.00021 21.7 0.2 2.1 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGR31822.1 - 0.00015 21.4 0.0 0.0025 17.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGR31822.1 - 0.00017 22.0 1.8 0.00019 21.8 0.2 1.9 2 1 0 2 2 1 1 AAA domain NB-ARC PF00931.22 EGR31822.1 - 0.00021 20.6 0.0 0.00041 19.6 0.0 1.5 1 1 0 1 1 1 1 NB-ARC domain DEAD PF00270.29 EGR31822.1 - 0.00025 20.9 0.9 0.065 13.0 0.1 2.7 2 1 1 3 3 3 1 DEAD/DEAH box helicase RuvB_N PF05496.12 EGR31822.1 - 0.00029 20.6 0.0 0.00045 20.0 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 EGR31822.1 - 0.0003 20.7 0.6 0.0013 18.7 0.1 2.3 2 1 0 2 2 1 1 NACHT domain Viral_helicase1 PF01443.18 EGR31822.1 - 0.00032 20.5 0.0 0.00053 19.8 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Cytidylate_kin PF02224.18 EGR31822.1 - 0.00034 20.4 0.1 0.00071 19.4 0.0 1.6 2 0 0 2 2 2 1 Cytidylate kinase AAA_2 PF07724.14 EGR31822.1 - 0.00034 20.8 0.0 0.00064 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) T2SSE PF00437.20 EGR31822.1 - 0.00049 19.2 0.0 0.00059 19.0 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase_2 PF01637.18 EGR31822.1 - 0.00064 19.7 0.7 0.0018 18.2 0.1 2.0 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea Polyoma_lg_T_C PF06431.11 EGR31822.1 - 0.00071 18.6 0.0 0.00087 18.3 0.0 1.2 1 0 0 1 1 1 1 Polyomavirus large T antigen C-terminus AAA_7 PF12775.7 EGR31822.1 - 0.00079 19.0 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ATPase PF06745.13 EGR31822.1 - 0.0016 17.8 0.1 0.005 16.2 0.0 1.7 1 1 1 2 2 2 1 KaiC KTI12 PF08433.10 EGR31822.1 - 0.0017 17.8 0.2 0.0031 17.0 0.0 1.4 2 0 0 2 2 1 1 Chromatin associated protein KTI12 AAA_3 PF07726.11 EGR31822.1 - 0.0019 18.1 0.0 0.0042 16.9 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EGR31822.1 - 0.002 18.0 1.9 0.12 12.1 0.1 2.4 2 1 1 3 3 2 1 AAA domain SKI PF01202.22 EGR31822.1 - 0.0043 17.2 0.0 0.0085 16.2 0.0 1.5 1 0 0 1 1 1 1 Shikimate kinase Mg_chelatase PF01078.21 EGR31822.1 - 0.0044 16.4 0.2 0.016 14.6 0.1 1.7 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI RsgA_GTPase PF03193.16 EGR31822.1 - 0.0046 16.9 0.0 0.007 16.3 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase RNA_helicase PF00910.22 EGR31822.1 - 0.0049 17.2 0.1 0.012 15.9 0.0 1.8 2 0 0 2 2 1 1 RNA helicase TniB PF05621.11 EGR31822.1 - 0.0053 16.2 0.2 0.53 9.7 0.2 2.3 1 1 0 1 1 1 1 Bacterial TniB protein cobW PF02492.19 EGR31822.1 - 0.0054 16.3 0.1 0.012 15.3 0.0 1.6 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain DUF2075 PF09848.9 EGR31822.1 - 0.0083 15.4 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 EGR31822.1 - 0.0091 16.1 0.0 0.019 15.1 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain G-alpha PF00503.20 EGR31822.1 - 0.015 14.5 1.4 0.02 14.1 0.3 1.6 1 1 0 1 1 1 0 G-protein alpha subunit SRP54 PF00448.22 EGR31822.1 - 0.017 14.8 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SMC_N PF02463.19 EGR31822.1 - 0.018 14.5 0.0 1.5 8.2 0.0 2.3 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGR31822.1 - 0.019 14.7 0.0 0.034 13.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain VirE PF05272.11 EGR31822.1 - 0.02 14.6 0.2 0.04 13.7 0.0 1.5 2 0 0 2 2 1 0 Virulence-associated protein E AAA_8 PF12780.7 EGR31822.1 - 0.023 14.0 0.0 0.044 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Thymidylate_kin PF02223.17 EGR31822.1 - 0.025 14.3 0.1 0.097 12.3 0.1 1.9 1 1 1 2 2 2 0 Thymidylate kinase PhoH PF02562.16 EGR31822.1 - 0.028 13.9 0.0 0.064 12.7 0.0 1.6 1 1 0 1 1 1 0 PhoH-like protein ATP_bind_1 PF03029.17 EGR31822.1 - 0.031 14.1 0.1 0.078 12.7 0.0 1.7 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein dNK PF01712.19 EGR31822.1 - 0.043 13.7 0.0 0.091 12.6 0.0 1.6 1 0 0 1 1 1 0 Deoxynucleoside kinase PRK PF00485.18 EGR31822.1 - 0.048 13.4 0.2 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Parvo_NS1 PF01057.17 EGR31822.1 - 0.05 12.7 0.0 0.095 11.8 0.0 1.7 1 1 0 1 1 1 0 Parvovirus non-structural protein NS1 ADK PF00406.22 EGR31822.1 - 0.055 13.6 0.2 0.13 12.4 0.2 1.8 1 1 0 1 1 1 0 Adenylate kinase ResIII PF04851.15 EGR31822.1 - 0.059 13.4 1.0 1.9 8.5 0.0 2.3 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit Ploopntkinase3 PF18751.1 EGR31822.1 - 0.064 13.2 0.0 0.091 12.7 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 CPT PF07931.12 EGR31822.1 - 0.069 13.0 0.0 0.099 12.5 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Sigma54_activat PF00158.26 EGR31822.1 - 0.076 12.7 0.0 0.14 11.9 0.0 1.5 1 1 0 1 1 1 0 Sigma-54 interaction domain APS_kinase PF01583.20 EGR31822.1 - 0.098 12.5 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_6 PF12774.7 EGR31822.1 - 0.13 11.2 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region GDA1_CD39 PF01150.17 EGR31824.1 - 1.1e-20 73.7 4.1 1.8e-20 73.0 4.1 1.2 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family EF-hand_6 PF13405.6 EGR31825.1 - 0.0024 17.7 0.1 0.012 15.5 0.1 2.2 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 EGR31825.1 - 0.011 15.2 0.1 0.045 13.3 0.1 2.1 1 0 0 1 1 1 0 EF hand EF-hand_5 PF13202.6 EGR31825.1 - 0.043 13.3 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 EF hand EF-hand_7 PF13499.6 EGR31825.1 - 0.049 14.1 0.9 0.16 12.4 0.2 2.2 1 1 1 2 2 2 0 EF-hand domain pair GDA1_CD39 PF01150.17 EGR31826.1 - 2e-65 221.1 0.6 2.7e-65 220.7 0.6 1.0 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family MutL PF13941.6 EGR31826.1 - 0.081 11.5 0.0 0.14 10.7 0.0 1.3 1 0 0 1 1 1 0 MutL protein Ppx-GppA PF02541.16 EGR31826.1 - 0.13 11.6 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Ppx/GppA phosphatase family WD40 PF00400.32 EGR31827.1 - 1.6e-06 28.7 5.9 0.22 12.4 0.0 5.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Synapsin PF02078.16 EGR31827.1 - 0.092 13.0 2.3 1 9.7 0.3 2.9 1 1 1 2 2 2 0 Synapsin, N-terminal domain Transp_Tc5_C PF04236.15 EGR31827.1 - 0.12 12.7 3.6 0.31 11.4 2.5 2.3 2 0 0 2 2 2 0 Tc5 transposase C-terminal domain Vps16_N PF04841.13 EGR31828.1 - 6.2e-28 97.7 3.0 1.6e-27 96.3 0.3 2.3 1 1 0 2 2 2 1 Vps16, N-terminal region Vps16_C PF04840.12 EGR31828.1 - 2e-22 79.6 15.8 2e-22 79.6 15.8 2.1 2 0 0 2 2 2 1 Vps16, C-terminal region Pkinase PF00069.25 EGR31829.1 - 1.5e-75 254.0 0.1 1.8e-75 253.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31829.1 - 5.9e-49 166.7 0.0 7.7e-49 166.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31829.1 - 0.00021 20.7 0.0 0.00037 19.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR31829.1 - 0.0044 16.4 0.2 0.0065 15.9 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR31829.1 - 0.0056 15.5 0.1 0.0074 15.1 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EGR31829.1 - 0.039 13.6 2.7 0.2 11.2 2.7 1.9 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGR31829.1 - 0.089 12.7 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ras PF00071.22 EGR31830.1 - 3.1e-47 160.2 1.6 3.1e-47 160.2 1.6 2.1 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EGR31830.1 - 1e-25 90.3 0.4 1e-25 90.3 0.4 2.3 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR31830.1 - 2e-08 33.9 0.2 2e-08 33.9 0.2 2.1 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR31830.1 - 0.03 14.4 0.0 0.03 14.4 0.0 2.6 2 1 0 2 2 2 0 50S ribosome-binding GTPase CoaE PF01121.20 EGR31830.1 - 0.24 11.1 9.3 0.3 10.7 7.6 1.9 2 0 0 2 2 2 0 Dephospho-CoA kinase DUF4460 PF14687.6 EGR31830.1 - 4.6 7.3 20.6 0.34 11.0 6.3 3.4 2 2 1 3 3 3 0 Domain of unknown function (DUF4460) ABC2_membrane PF01061.24 EGR31832.1 - 2.7e-35 121.7 16.9 5.2e-35 120.8 16.9 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGR31832.1 - 5e-25 88.6 0.4 2e-24 86.7 0.4 2.1 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGR31832.1 - 3.9e-08 32.8 22.6 3.9e-08 32.8 22.6 1.9 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGR31832.1 - 8.2e-05 22.6 0.6 0.24 11.2 0.1 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGR31832.1 - 9e-05 22.9 0.0 0.00016 22.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGR31832.1 - 0.00024 21.4 0.2 0.0013 19.0 0.2 2.3 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EGR31832.1 - 0.00062 19.7 0.0 0.072 13.0 0.0 2.6 2 0 0 2 2 2 1 NTPase AAA_18 PF13238.6 EGR31832.1 - 0.0025 18.4 0.1 0.0087 16.6 0.1 2.0 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGR31832.1 - 0.0068 16.3 0.1 0.021 14.7 0.1 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 EGR31832.1 - 0.022 14.5 0.0 0.035 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EGR31832.1 - 0.027 13.7 2.1 0.047 12.9 0.0 2.4 3 0 0 3 3 3 0 NB-ARC domain PRK PF00485.18 EGR31832.1 - 0.029 14.1 0.1 0.16 11.7 0.0 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family TsaE PF02367.17 EGR31832.1 - 0.029 14.4 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EGR31832.1 - 0.03 14.7 0.1 0.28 11.6 0.0 2.8 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 EGR31832.1 - 0.031 14.0 0.4 0.1 12.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EGR31832.1 - 0.055 13.2 0.1 0.52 10.0 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.6 EGR31832.1 - 0.066 13.0 0.2 0.18 11.6 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain cobW PF02492.19 EGR31832.1 - 0.075 12.6 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EGR31832.1 - 0.093 12.6 0.0 0.22 11.4 0.0 1.7 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 EGR31832.1 - 0.12 12.5 0.0 0.38 10.8 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase MobB PF03205.14 EGR31832.1 - 0.12 12.3 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B DUF87 PF01935.17 EGR31832.1 - 0.22 11.6 3.5 0.24 11.5 0.0 2.7 3 0 0 3 3 3 0 Helicase HerA, central domain ILEI PF15711.5 EGR31833.1 - 0.018 15.5 0.2 0.16 12.5 0.2 2.7 1 0 0 1 1 1 0 Interleukin-like EMT inducer MORN PF02493.20 EGR31834.1 - 6.2e-29 98.2 29.7 5e-09 35.5 0.9 5.7 5 0 0 5 5 5 5 MORN repeat TFIIA PF03153.13 EGR31834.1 - 0.82 9.6 25.3 1 9.3 25.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fmp27_WPPW PF10359.9 EGR31834.1 - 1.2 8.0 18.0 0.057 12.3 1.8 2.1 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF702 PF05142.12 EGR31834.1 - 2 8.9 7.7 4.2 7.8 7.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) NPAT_C PF15712.5 EGR31834.1 - 9.4 4.7 16.5 13 4.3 16.5 1.1 1 0 0 1 1 1 0 NPAT C terminus AlbA_2 PF04326.14 EGR31834.1 - 9.7 6.5 10.8 11 6.3 5.9 2.5 2 0 0 2 2 2 0 Putative DNA-binding domain WD40 PF00400.32 EGR31836.1 - 5.3e-12 46.1 3.1 0.0016 19.2 0.0 5.0 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR31836.1 - 9.7e-06 25.8 3.2 0.11 12.8 0.2 3.7 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DUF2948 PF11164.8 EGR31836.1 - 0.074 13.1 0.1 0.18 11.8 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2948) DUF1126 PF06565.12 EGR31837.1 - 1.3e-81 269.2 12.4 9.4e-29 99.3 0.7 3.4 3 0 0 3 3 3 3 DUF1126 PH-like domain RHH_7 PF16777.5 EGR31837.1 - 0.42 11.0 0.0 0.42 11.0 0.0 2.9 3 0 0 3 3 3 0 Transcriptional regulator, RHH-like, CopG Pkinase PF00069.25 EGR31838.1 - 6.5e-68 228.9 5.1 6.5e-68 228.9 5.1 2.2 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31838.1 - 3.5e-43 147.7 1.4 3.5e-43 147.7 1.4 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EGR31838.1 - 3.9e-06 26.4 0.1 3.9e-06 26.4 0.1 1.9 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR31838.1 - 0.071 13.0 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Inositol_P PF00459.25 EGR31838.1 - 0.9 9.0 4.2 1.6 8.1 4.2 1.4 1 0 0 1 1 1 0 Inositol monophosphatase family DUF2284 PF10050.9 EGR31838.1 - 1.3 8.8 6.8 1.1 8.9 0.0 2.5 2 0 0 2 2 2 0 Predicted metal-binding protein (DUF2284) Ribosomal_S14 PF00253.21 EGR31840.1 - 7.6e-14 51.2 3.0 8.3e-14 51.1 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e zf-P11 PF03854.14 EGR31840.1 - 0.038 13.6 1.7 0.057 13.1 1.7 1.2 1 0 0 1 1 1 0 P-11 zinc finger zf-CCHC_2 PF13696.6 EGR31840.1 - 0.15 11.9 0.4 0.15 11.9 0.4 2.5 3 0 0 3 3 3 0 Zinc knuckle WD40 PF00400.32 EGR31841.1 - 9.2e-40 133.9 18.5 1.4e-07 32.1 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR31841.1 - 3.6e-06 27.2 3.8 1.5 9.1 0.0 5.3 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGR31841.1 - 0.09 11.4 0.2 0.33 9.5 0.0 2.0 2 1 0 2 2 2 0 Nucleoporin Nup120/160 Pkinase PF00069.25 EGR31844.1 - 1.7e-27 96.5 0.1 3.3e-27 95.5 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain EF-hand_1 PF00036.32 EGR31844.1 - 1.6e-25 86.7 9.6 3.9e-07 29.1 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGR31844.1 - 4.9e-23 81.4 4.1 1.2e-11 44.9 0.2 2.7 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EGR31844.1 - 1.3e-22 78.2 7.8 3.4e-06 26.3 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGR31844.1 - 2.9e-22 76.6 4.4 2.7e-07 30.0 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGR31844.1 - 1.7e-14 53.4 7.3 0.0045 16.8 0.1 4.6 3 1 1 4 4 4 4 EF-hand domain pair Pkinase_Tyr PF07714.17 EGR31844.1 - 1.6e-10 40.7 0.0 3.4e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase SPARC_Ca_bdg PF10591.9 EGR31844.1 - 1.1e-08 35.4 2.1 0.00022 21.5 0.5 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGR31844.1 - 3.5e-05 23.7 3.3 0.012 15.6 0.2 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.10 EGR31844.1 - 0.00036 20.5 1.6 3 8.0 0.3 3.4 3 0 0 3 3 3 2 Ca2+ insensitive EF hand Caleosin PF05042.13 EGR31844.1 - 0.00044 20.2 0.2 0.037 14.0 0.0 2.4 1 1 0 2 2 2 1 Caleosin related protein Dockerin_1 PF00404.18 EGR31844.1 - 0.018 15.3 1.6 3.2 8.0 0.0 3.7 2 1 1 3 3 3 0 Dockerin type I domain Kinase-like PF14531.6 EGR31844.1 - 0.025 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Band_7 PF01145.25 EGR31845.1 - 4.4e-29 101.7 0.3 9.2e-29 100.7 0.3 1.6 1 0 0 1 1 1 1 SPFH domain / Band 7 family Cpn60_TCP1 PF00118.24 EGR31846.1 - 2.1e-147 491.7 12.1 2.5e-147 491.5 12.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TLD PF07534.16 EGR31847.1 - 1.9e-30 105.9 2.5 1.9e-30 105.9 2.5 2.7 3 1 0 3 3 3 1 TLD LysM PF01476.20 EGR31847.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.3 2 1 1 3 3 3 0 LysM domain SKICH PF17751.1 EGR31847.1 - 1.2 9.8 6.2 5.6 7.6 0.7 2.9 2 0 0 2 2 2 0 SKICH domain Kinesin PF00225.23 EGR31848.1 - 2.1e-75 253.7 1.7 2.8e-75 253.3 1.7 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR31848.1 - 6.7e-07 29.4 2.9 5.6e-06 26.4 0.9 2.9 2 1 0 2 2 2 1 Microtubule binding IFT57 PF10498.9 EGR31851.1 - 4.9e-82 275.8 35.8 7e-82 275.3 35.8 1.2 1 0 0 1 1 1 1 Intra-flagellar transport protein 57 Pkinase PF00069.25 EGR31851.1 - 3.5e-64 216.7 2.1 3.5e-64 216.7 2.1 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31851.1 - 1.8e-44 152.0 0.2 1.8e-44 152.0 0.2 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EGR31851.1 - 0.0011 18.4 0.2 0.0011 18.4 0.2 2.1 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family PSP1 PF04468.12 EGR31851.1 - 0.0044 17.3 0.8 2.7 8.3 2.7 3.6 2 2 1 3 3 3 1 PSP1 C-terminal conserved region APH PF01636.23 EGR31851.1 - 0.1 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mito_carr PF00153.27 EGR31852.1 - 3e-42 142.5 1.1 5.7e-14 51.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Bac_export_2 PF01312.19 EGR31852.1 - 0.0004 19.7 1.4 0.0015 17.9 1.3 1.8 1 1 0 1 1 1 1 FlhB HrpN YscU SpaS Family UPF0093 PF03653.13 EGR31852.1 - 0.0046 17.2 1.9 0.033 14.4 0.2 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0093) CDC24_OB3 PF17244.2 EGR31854.1 - 0.0099 15.6 0.8 0.012 15.4 0.8 1.1 1 0 0 1 1 1 1 Cell division control protein 24, OB domain 3 MORN PF02493.20 EGR31855.1 - 1.6e-12 46.5 19.2 2.3e-07 30.3 1.2 3.9 3 1 0 3 3 3 2 MORN repeat Ribosomal_L4 PF00573.22 EGR31855.1 - 0.13 11.9 0.0 0.17 11.6 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L4/L1 family MORN_2 PF07661.13 EGR31855.1 - 1.6 9.2 14.3 1.3 9.5 0.3 5.3 4 1 1 5 5 5 0 MORN repeat variant Pkinase PF00069.25 EGR31856.1 - 1.4e-40 139.4 1.3 1.7e-40 139.1 1.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31856.1 - 4.6e-17 62.2 0.1 8.3e-17 61.3 0.1 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase IFS PF16718.5 EGR31857.1 - 0.03 14.4 9.6 0.036 14.1 9.6 1.2 1 0 0 1 1 1 0 Immunity factor for SPN OAD_gamma PF04277.13 EGR31857.1 - 5.7 7.6 7.3 1.4 9.5 0.8 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF2254 PF10011.9 EGR31858.1 - 0.85 8.4 3.6 4.5 6.0 0.1 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2254) C2-C2_1 PF11618.8 EGR31859.1 - 1.3e-32 112.8 0.4 3.5e-32 111.4 0.1 1.9 2 0 0 2 2 2 1 First C2 domain of RPGR-interacting protein 1 EF-hand_1 PF00036.32 EGR31859.1 - 0.011 15.2 2.0 0.017 14.6 0.3 2.2 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 EGR31859.1 - 0.024 14.5 0.1 0.12 12.3 0.1 2.3 1 0 0 1 1 1 0 EF-hand domain Glyco_hydro_31 PF01055.26 EGR31860.1 - 5.4e-107 358.7 13.7 8.6e-107 358.0 13.7 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EGR31860.1 - 2.2e-11 43.9 1.9 4.9e-11 42.8 0.4 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 EGR31860.1 - 2.9e-07 30.7 1.4 5.4e-07 29.8 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) DUF4968 PF16338.5 EGR31860.1 - 0.0024 18.2 0.7 0.0058 16.9 0.7 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4968) Baculo_RING PF05883.11 EGR31860.1 - 0.079 13.0 1.8 0.19 11.7 1.8 1.6 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain TraD_N PF12615.8 EGR31862.1 - 1.1 10.1 5.1 0.4 11.5 1.6 1.9 2 0 0 2 2 2 0 F sex factor protein N terminal TTL PF03133.15 EGR31863.1 - 6.1e-83 278.3 2.8 6.1e-83 278.3 2.8 1.4 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR31863.1 - 5.9e-07 29.0 0.3 0.0055 16.0 0.0 3.5 2 2 1 3 3 3 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR31863.1 - 5.2e-06 25.9 0.0 0.00094 18.5 0.0 2.4 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EGR31863.1 - 0.014 15.5 0.0 0.21 11.6 0.0 2.4 2 0 0 2 2 2 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGR31863.1 - 0.047 13.2 0.0 0.093 12.3 0.0 1.5 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus ERGIC_N PF13850.6 EGR31864.1 - 0.00078 19.7 0.9 0.012 15.9 0.0 3.1 2 1 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DUF2552 PF10827.8 EGR31864.1 - 0.036 14.2 0.0 2.8 8.2 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2552) NGP1NT PF08153.12 EGR31865.1 - 2.6e-33 114.9 2.4 2.6e-33 114.9 2.4 1.9 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EGR31865.1 - 7.1e-16 58.3 0.3 8.9e-14 51.5 0.0 3.1 3 1 0 3 3 3 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGR31865.1 - 3e-05 23.6 0.1 0.58 9.7 0.1 3.6 2 1 0 3 3 3 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGR31865.1 - 0.00039 20.0 0.1 0.0015 18.1 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGR31865.1 - 0.0027 17.6 0.2 0.013 15.4 0.0 2.4 2 1 0 2 2 2 1 RsgA GTPase Arf PF00025.21 EGR31865.1 - 0.068 12.6 3.9 1.2 8.6 0.0 2.7 3 0 0 3 3 3 0 ADP-ribosylation factor family Pex26 PF07163.12 EGR31865.1 - 0.22 10.8 2.0 0.52 9.6 2.0 1.5 1 0 0 1 1 1 0 Pex26 protein EF-hand_7 PF13499.6 EGR31866.1 - 3.2e-20 72.3 4.4 1.6e-10 41.3 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGR31866.1 - 4.7e-18 64.8 2.8 5.1e-08 32.7 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR31866.1 - 3.4e-17 60.8 4.5 1.2e-05 24.9 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 EGR31866.1 - 1.1e-16 59.1 7.1 3.4e-06 26.2 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_11 PF08976.11 EGR31866.1 - 4.9e-07 30.6 0.8 0.015 16.1 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGR31866.1 - 1.1e-06 27.8 3.1 0.0004 19.8 0.1 3.3 3 0 0 3 3 3 2 EF hand p25-alpha PF05517.12 EGR31866.1 - 7.6e-06 26.2 2.3 0.0056 16.9 0.3 2.3 2 0 0 2 2 2 2 p25-alpha SPARC_Ca_bdg PF10591.9 EGR31866.1 - 1.5e-05 25.3 0.9 0.094 13.0 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region RST PF12174.8 EGR31866.1 - 0.00038 20.3 0.1 1.3 9.0 0.1 2.4 2 0 0 2 2 2 2 RCD1-SRO-TAF4 (RST) plant domain EF-hand_4 PF12763.7 EGR31866.1 - 0.0018 18.2 0.7 1.1 9.2 0.1 2.4 2 0 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand ATP-grasp PF02222.22 EGR31866.1 - 0.062 12.9 0.2 0.61 9.6 0.0 2.1 2 0 0 2 2 2 0 ATP-grasp domain DUF1456 PF07308.13 EGR31866.1 - 0.088 13.2 1.8 1.2 9.6 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1456) Casein_kappa PF00997.18 EGR31867.1 - 0.038 14.1 3.5 0.08 13.0 0.3 2.6 2 0 0 2 2 2 0 Kappa casein Furin-like_2 PF15913.5 EGR31868.1 - 0.00045 20.3 23.3 0.00083 19.5 11.3 7.1 3 1 4 7 7 7 5 Furin-like repeat, cysteine-rich VSP PF03302.13 EGR31868.1 - 6.5 5.5 85.2 0.89 8.3 27.1 6.2 2 1 3 5 5 5 0 Giardia variant-specific surface protein DUF1319 PF07028.11 EGR31871.1 - 0.013 15.7 1.5 0.061 13.5 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1319) HTH_40 PF14493.6 EGR31871.1 - 0.059 13.8 1.0 0.66 10.5 0.2 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain FliT PF05400.13 EGR31871.1 - 0.15 12.9 1.1 0.3 11.9 0.4 1.8 2 0 0 2 2 2 0 Flagellar protein FliT Pkinase PF00069.25 EGR31872.1 - 2.4e-48 164.8 0.2 2.6e-48 164.7 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31872.1 - 4e-25 88.6 0.0 4.7e-25 88.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31872.1 - 7.7e-10 38.6 0.0 1.3e-09 37.8 0.0 1.3 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR31872.1 - 2.5e-05 23.3 0.0 3.2e-05 22.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR31872.1 - 0.00016 21.1 0.0 0.00022 20.7 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR31872.1 - 0.00047 20.2 0.0 0.00062 19.8 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGR31872.1 - 0.00057 19.5 0.3 0.00087 18.9 0.3 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Haspin_kinase PF12330.8 EGR31872.1 - 0.011 14.7 0.2 0.018 14.0 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain CRAL_TRIO PF00650.20 EGR31873.1 - 0.011 15.4 0.0 0.021 14.6 0.0 1.4 1 0 0 1 1 1 0 CRAL/TRIO domain Importin_rep_5 PF18816.1 EGR31874.1 - 0.061 13.6 0.1 0.061 13.6 0.1 2.0 2 0 0 2 2 2 0 Importin repeat HEPN_RES_NTD1 PF18870.1 EGR31874.1 - 0.069 13.3 1.6 0.15 12.2 1.4 1.7 1 1 0 1 1 1 0 HEPN/RES N-terminal domain 1 CHASE6_C PF17150.4 EGR31874.1 - 0.47 11.2 5.5 0.19 12.4 1.1 2.7 3 0 0 3 3 3 0 C-terminal domain of two-partite extracellular sensor domain GBP PF02263.19 EGR31875.1 - 5.3e-32 111.1 11.7 5.3e-32 111.1 11.7 2.7 2 1 1 3 3 3 1 Guanylate-binding protein, N-terminal domain YmaF PF12788.7 EGR31875.1 - 0.13 12.8 0.1 0.42 11.2 0.1 1.8 1 0 0 1 1 1 0 YmaF family DNA_pol_alpha_N PF12254.8 EGR31875.1 - 3.3 7.9 6.2 1.6 8.9 0.4 3.3 3 0 0 3 3 3 0 DNA polymerase alpha subunit p180 N terminal Dynamin_N PF00350.23 EGR31875.1 - 4.3 7.4 0.0 4.3 7.4 0.0 4.4 4 1 0 4 4 4 0 Dynamin family CYTL1 PF15153.6 EGR31876.1 - 0.046 13.7 0.1 0.19 11.7 0.1 2.1 1 0 0 1 1 1 0 Cytokine-like protein 1 HECT PF00632.25 EGR31879.1 - 9.3e-30 104.2 0.9 1.1e-29 103.9 0.9 1.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Colicin_K PF17500.2 EGR31879.1 - 0.091 13.3 0.2 0.14 12.7 0.2 1.5 1 0 0 1 1 1 0 Colicin-K Pkinase PF00069.25 EGR31880.1 - 4.4e-75 252.4 0.7 6.7e-75 251.9 0.7 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31880.1 - 4.1e-46 157.4 0.1 6.2e-46 156.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31880.1 - 1.3e-10 41.1 0.0 5.6e-10 39.0 0.0 1.9 1 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGR31880.1 - 0.0001 21.4 0.3 0.0002 20.4 0.3 1.6 1 0 0 1 1 1 1 Haspin like kinase domain YukC PF10140.9 EGR31880.1 - 0.00024 20.1 2.5 0.00052 19.0 2.5 1.5 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukC Kdo PF06293.14 EGR31880.1 - 0.00074 18.9 0.2 0.0018 17.7 0.2 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGR31880.1 - 0.0023 17.5 2.8 0.029 13.9 0.4 2.4 2 1 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EGR31880.1 - 0.003 17.5 0.0 0.0048 16.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family WD40 PF00400.32 EGR31881.1 - 0.00014 22.6 0.2 0.007 17.2 0.0 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat Nup160 PF11715.8 EGR31881.1 - 0.00066 18.5 0.1 0.014 14.1 0.0 2.2 1 1 0 2 2 2 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGR31881.1 - 0.00082 19.6 0.3 1.1 9.6 0.0 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain SBDS PF01172.18 EGR31881.1 - 5.3 7.2 7.8 3.1 7.9 5.0 2.1 2 1 0 2 2 2 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein UBA PF00627.31 EGR31882.1 - 2.2e-26 91.3 0.4 1.9e-13 50.0 0.1 2.7 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 EGR31882.1 - 5.5e-16 58.1 23.5 5.5e-16 58.1 23.5 2.4 2 0 0 2 2 1 1 XPC-binding domain ubiquitin PF00240.23 EGR31882.1 - 1.5e-07 31.0 1.7 2.4e-07 30.4 0.3 2.1 2 0 0 2 2 2 1 Ubiquitin family UBA_3 PF09288.10 EGR31882.1 - 0.0002 21.1 7.2 0.0024 17.6 0.0 3.1 3 1 0 3 3 2 2 Fungal ubiquitin-associated domain Rad60-SLD PF11976.8 EGR31882.1 - 0.0004 20.2 0.4 0.0018 18.1 0.4 2.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EGR31882.1 - 0.00091 19.3 0.5 0.00091 19.3 0.5 2.3 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like CUE PF02845.16 EGR31882.1 - 0.0091 15.7 0.0 1.9 8.3 0.0 2.7 2 0 0 2 2 2 1 CUE domain AIF_C PF14721.6 EGR31882.1 - 2.9 8.2 12.5 5.4 7.4 0.1 2.5 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2407 PF10302.9 EGR31882.1 - 4.2 8.0 11.0 0.21 12.2 1.0 2.6 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain TCP PF03634.13 EGR31882.1 - 6.1 7.4 13.1 1.8 9.1 5.2 2.4 2 0 0 2 2 2 0 TCP family transcription factor DUF3306 PF11748.8 EGR31882.1 - 8.7 7.2 15.2 0.45 11.4 2.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) Peptidase_M24 PF00557.24 EGR31883.1 - 5.2e-47 160.2 0.0 6.8e-47 159.9 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EGR31883.1 - 1.4e-17 63.7 7.7 2.7e-17 62.8 7.7 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EGR31883.1 - 0.0028 17.7 3.7 0.0077 16.3 3.7 1.8 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 EGR31883.1 - 4 7.4 8.2 5 7.1 5.8 2.2 2 0 0 2 2 2 0 HIT zinc finger Kinesin PF00225.23 EGR31884.1 - 3.2e-82 276.1 8.0 3.2e-82 276.1 8.0 2.0 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGR31884.1 - 3.7e-22 78.9 2.6 3.7e-22 78.9 2.6 3.4 3 1 0 3 3 3 1 Microtubule binding BBS2_N PF14781.6 EGR31884.1 - 0.0044 16.9 0.1 0.016 15.1 0.1 2.0 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, N-terminal FANCI_S2 PF14676.6 EGR31884.1 - 3.5 7.9 6.0 3.1 8.1 1.2 2.7 2 1 0 2 2 2 0 FANCI solenoid 2 Ank_2 PF12796.7 EGR31885.1 - 1.3e-29 102.6 9.2 2e-15 57.1 0.5 3.2 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Bromodomain PF00439.25 EGR31885.1 - 1.1e-19 70.2 3.5 1.2e-19 70.2 0.3 2.7 3 0 0 3 3 3 1 Bromodomain Ank_4 PF13637.6 EGR31885.1 - 9.4e-18 64.3 0.6 4.5e-06 27.1 0.1 4.0 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR31885.1 - 1.8e-14 52.4 0.8 0.00036 20.8 0.1 5.2 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 EGR31885.1 - 1.4e-12 47.4 0.0 0.0016 18.8 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EGR31885.1 - 1.6e-08 34.6 0.2 0.0011 19.2 0.0 3.2 2 1 1 3 3 2 2 Ankyrin repeats (many copies) Spt20 PF12090.8 EGR31885.1 - 0.013 15.1 58.1 0.031 13.9 24.4 2.4 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 EGR31885.1 - 0.022 14.8 51.6 0.016 15.2 20.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 EGR31885.1 - 1.1 9.3 26.0 0.53 10.3 7.5 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.17 EGR31885.1 - 1.3 9.1 18.3 0.99 9.5 4.0 2.3 2 0 0 2 2 2 0 DDHD domain MMR1 PF08505.10 EGR31885.1 - 2.1 8.5 36.6 0.82 9.9 12.9 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein SLC12 PF03522.15 EGR31885.1 - 5.9 5.8 35.9 0.51 9.3 13.7 2.1 2 0 0 2 2 2 0 Solute carrier family 12 HemY_N PF07219.13 EGR31886.1 - 0.38 11.0 1.4 0.45 10.7 1.4 1.1 1 0 0 1 1 1 0 HemY protein N-terminus Ac76 PF05814.11 EGR31886.1 - 1.9 8.6 14.3 2.8 8.0 14.3 1.3 1 0 0 1 1 1 0 Orf76 (Ac76) Wzy_C PF04932.15 EGR31886.1 - 2.8 7.6 11.2 3.1 7.4 11.2 1.1 1 0 0 1 1 1 0 O-Antigen ligase DUF3810 PF12725.7 EGR31886.1 - 2.9 7.2 7.2 3 7.1 7.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) DUF2207 PF09972.9 EGR31886.1 - 8 5.1 10.5 8.3 5.0 10.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) adh_short PF00106.25 EGR31887.1 - 1.3e-10 41.0 0.1 1.6e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGR31887.1 - 1.5e-06 28.0 0.0 1.7e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGR31887.1 - 0.029 14.3 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 KR domain RNase_PH_C PF03725.15 EGR31888.1 - 1e-07 31.9 0.0 4.7e-07 29.8 0.0 2.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RNase_PH PF01138.21 EGR31888.1 - 3.6e-05 24.3 0.0 7.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 LPP20 PF02169.16 EGR31888.1 - 0.077 13.4 1.0 0.077 13.4 1.0 1.7 2 0 0 2 2 2 0 LPP20 lipoprotein Nic96 PF04097.14 EGR31889.1 - 0.02 13.3 1.3 0.024 13.1 1.3 1.2 1 0 0 1 1 1 0 Nup93/Nic96 VitK2_biosynth PF02621.14 EGR31889.1 - 0.11 12.1 0.1 0.11 12.0 0.1 1.0 1 0 0 1 1 1 0 Menaquinone biosynthesis TPR_19 PF14559.6 EGR31890.1 - 1.2e-23 83.3 41.3 1.5e-07 31.8 0.1 12.5 11 3 4 15 15 14 6 Tetratricopeptide repeat DPCD PF14913.6 EGR31890.1 - 3e-22 78.9 5.2 7.3e-22 77.6 5.2 1.7 1 0 0 1 1 1 1 DPCD protein family TPR_14 PF13428.6 EGR31890.1 - 1.1e-17 63.2 5.1 0.2 12.6 0.0 11.5 9 3 5 14 14 12 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGR31890.1 - 3.3e-14 51.8 41.3 0.018 15.2 2.1 12.6 15 0 0 15 15 11 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR31890.1 - 2.7e-13 50.0 43.6 2.8e-05 24.3 0.1 9.4 7 1 3 10 10 9 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EGR31890.1 - 1.7e-12 47.8 1.0 0.0034 18.0 0.3 6.8 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGR31890.1 - 1.3e-11 43.8 29.1 0.035 14.0 0.0 9.7 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGR31890.1 - 3.5e-11 43.2 12.6 0.019 15.3 0.0 8.9 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGR31890.1 - 2.6e-10 39.6 10.4 1.1 9.5 0.1 8.6 7 1 1 8 8 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 EGR31890.1 - 8.6e-06 25.8 0.0 0.0059 16.7 0.1 4.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGR31890.1 - 1.6e-05 24.5 21.6 0.14 11.8 0.4 7.3 7 1 1 8 8 8 3 TPR repeat TPR_8 PF13181.6 EGR31890.1 - 0.00017 21.5 41.1 0.81 10.1 0.1 12.9 13 1 1 14 14 14 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGR31890.1 - 0.00046 20.4 25.8 3.1 8.4 1.7 9.2 9 0 0 9 9 6 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EGR31890.1 - 0.001 18.7 0.5 0.31 10.7 0.0 4.6 5 1 0 5 5 5 1 Bacterial type III secretion protein (HrpB1_HrpK) Phenyl_P_gamma PF09662.10 EGR31890.1 - 0.0051 17.0 0.3 0.69 10.1 0.0 3.6 3 0 0 3 3 3 1 Phenylphosphate carboxylase gamma subunit (Phenyl_P_gamma) TPR_20 PF14561.6 EGR31890.1 - 0.0052 17.1 14.7 0.5 10.7 0.1 7.2 8 1 1 9 9 9 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGR31890.1 - 0.024 15.3 28.3 0.16 12.7 0.1 10.8 12 0 0 12 12 10 0 Tetratricopeptide repeat BTAD PF03704.17 EGR31890.1 - 0.038 14.4 2.8 4.3 7.8 0.1 4.5 4 1 1 5 5 5 0 Bacterial transcriptional activator domain Sel1 PF08238.12 EGR31890.1 - 0.052 14.2 0.6 47 4.9 0.2 4.5 3 0 0 3 3 3 0 Sel1 repeat PknG_TPR PF16918.5 EGR31890.1 - 0.12 11.1 0.0 14 4.2 0.0 3.2 3 0 0 3 3 3 0 Protein kinase G tetratricopeptide repeat TTL PF03133.15 EGR31891.1 - 1.4e-83 280.5 7.9 1.4e-83 280.5 7.9 3.1 2 1 1 3 3 3 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR31891.1 - 3.4e-05 23.2 0.0 3.4e-05 23.2 0.0 4.6 3 2 0 3 3 3 2 YheC/D like ATP-grasp Flavi_NS1 PF00948.21 EGR31891.1 - 0.012 14.5 1.3 0.029 13.2 0.0 2.0 2 0 0 2 2 2 0 Flavivirus non-structural Protein NS1 TFIIA PF03153.13 EGR31891.1 - 0.78 9.7 29.5 1.1 9.1 29.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cpn60_TCP1 PF00118.24 EGR31892.1 - 3.1e-152 507.6 17.7 3.5e-152 507.5 17.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Aldo_ket_red PF00248.21 EGR31893.1 - 3e-44 151.4 0.6 2.7e-42 145.0 0.6 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family Kelch_6 PF13964.6 EGR31894.1 - 2.5e-08 33.9 0.0 4e-08 33.2 0.0 1.4 1 0 0 1 1 1 1 Kelch motif Kelch_3 PF13415.6 EGR31894.1 - 7.4e-08 32.5 0.1 1.1e-07 31.9 0.1 1.3 1 0 0 1 1 1 1 Galactose oxidase, central domain Kelch_2 PF07646.15 EGR31894.1 - 8.9e-06 25.5 0.0 3.4e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.6 EGR31894.1 - 1.1e-05 25.3 1.4 1.3e-05 25.1 0.2 1.7 2 0 0 2 2 2 1 Galactose oxidase, central domain Kelch_5 PF13854.6 EGR31894.1 - 0.00033 20.5 0.0 0.0013 18.6 0.0 1.9 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.25 EGR31894.1 - 0.0011 18.6 0.4 0.0034 16.9 0.1 2.0 1 1 1 2 2 2 1 Kelch motif C2 PF00168.30 EGR31895.1 - 1.6e-05 25.1 0.0 3e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 C2 domain CdiI_N PF18228.1 EGR31895.1 - 0.064 13.1 1.3 0.45 10.4 0.2 2.1 1 1 1 2 2 2 0 CdiI N-terminal domain Filament PF00038.21 EGR31896.1 - 0.00022 20.9 22.1 0.00022 20.9 22.1 5.6 1 1 4 5 5 5 4 Intermediate filament protein Pkinase PF00069.25 EGR31897.1 - 3.7e-57 193.7 0.1 6.2e-57 192.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31897.1 - 4e-35 121.3 0.0 5.6e-35 120.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31897.1 - 0.0024 17.2 0.0 0.0039 16.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR31897.1 - 0.0029 16.5 0.1 0.0057 15.5 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGR31897.1 - 0.0039 16.2 0.1 0.0039 16.2 0.1 2.3 2 1 0 2 2 2 1 Haspin like kinase domain RIO1 PF01163.22 EGR31897.1 - 0.012 15.3 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family EF-hand_7 PF13499.6 EGR31897.1 - 0.078 13.4 0.6 4.3 7.9 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair APH PF01636.23 EGR31897.1 - 0.16 11.9 0.0 1.1 9.1 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family PAS_9 PF13426.7 EGR31898.1 - 1.1e-06 28.8 2.7 3.8e-06 27.1 0.1 3.3 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EGR31898.1 - 0.0006 19.8 0.0 0.0022 18.0 0.0 2.0 1 0 0 1 1 1 1 PAS fold Peptidase_M24 PF00557.24 EGR31899.1 - 1.8e-39 135.6 0.0 3.6e-39 134.6 0.0 1.5 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 EGR31899.1 - 8.9e-37 126.7 4.7 3.7e-35 121.4 0.5 3.7 1 1 2 3 3 3 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 EGR31899.1 - 1.3e-23 82.8 0.5 5.6e-23 80.8 0.5 2.2 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 EGR31899.1 - 1.5e-11 45.1 0.0 3.5e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Creatinase/Prolidase N-terminal domain PK PF00224.21 EGR31899.1 - 0.021 13.7 0.2 0.032 13.1 0.2 1.3 1 0 0 1 1 1 0 Pyruvate kinase, barrel domain HECT PF00632.25 EGR31900.1 - 1.2e-59 202.3 1.7 1.2e-59 202.3 1.7 2.1 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) SNAPc19 PF15497.6 EGR31900.1 - 0.11 12.9 2.6 0.4 11.2 2.6 1.9 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 zf-RanBP PF00641.18 EGR31901.1 - 5.7e-07 28.7 4.8 1.4e-06 27.4 4.8 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Vps36-NZF-N PF16988.5 EGR31901.1 - 0.26 10.7 4.9 8.1 5.9 3.5 2.9 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain DUF3320 PF11784.8 EGR31903.1 - 0.12 12.3 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) DUF4064 PF13273.6 EGR31905.1 - 0.0079 16.5 1.0 0.0079 16.5 1.0 4.3 4 1 0 4 4 4 1 Protein of unknown function (DUF4064) UPF0524 PF15823.5 EGR31905.1 - 6.2 6.2 21.0 0.029 13.8 8.0 2.9 2 1 0 2 2 2 0 UPF0524 of C3orf70 HATPase_c PF02518.26 EGR31906.1 - 1.1e-23 83.9 0.7 2.1e-23 83.0 0.7 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGR31906.1 - 6.5e-18 64.9 1.2 1.8e-17 63.5 1.2 1.8 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EGR31906.1 - 8.4e-12 45.0 0.2 6.9e-11 42.0 0.0 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EGR31906.1 - 0.0099 15.7 1.5 0.018 14.9 0.1 2.1 2 1 1 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Usher PF00577.20 EGR31906.1 - 0.014 14.2 1.7 0.027 13.4 1.7 1.3 1 0 0 1 1 1 0 Outer membrane usher protein Peptidase_M16_M PF16187.5 EGR31907.1 - 1.9e-09 37.3 13.0 3.2e-08 33.2 4.3 3.2 3 0 0 3 3 3 2 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EGR31907.1 - 9.6e-09 35.4 0.2 9.6e-09 35.4 0.2 3.8 5 1 1 6 6 6 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGR31907.1 - 7.1e-07 29.4 13.4 0.0016 18.5 0.9 2.9 2 0 0 2 2 2 2 Peptidase M16 inactive domain VESA1_N PF12785.7 EGR31908.1 - 0.02 13.9 0.4 0.028 13.4 0.4 1.2 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 Ion_trans_2 PF07885.16 EGR31909.1 - 1e-11 44.7 3.7 1e-11 44.7 3.7 2.7 3 2 0 3 3 3 1 Ion channel Ion_trans PF00520.31 EGR31909.1 - 4.5e-09 35.9 34.9 7.6e-09 35.2 34.2 1.7 1 1 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EGR31909.1 - 0.00058 19.9 0.0 0.85 9.7 0.0 2.5 1 1 1 2 2 2 2 Cyclic nucleotide-binding domain CitMHS PF03600.16 EGR31909.1 - 1.4 8.0 4.0 2.2 7.4 4.0 1.2 1 0 0 1 1 1 0 Citrate transporter Furin-like_2 PF15913.5 EGR31910.1 - 0.00044 20.4 13.6 0.00044 20.4 13.6 4.3 2 2 1 3 3 3 2 Furin-like repeat, cysteine-rich Fer4 PF00037.27 EGR31910.1 - 0.94 9.4 0.0 0.94 9.4 0.0 6.5 6 2 2 8 8 8 0 4Fe-4S binding domain GF_recep_IV PF14843.6 EGR31910.1 - 3.2 7.6 66.4 0.26 11.1 17.4 4.2 4 1 0 4 4 4 0 Growth factor receptor domain IV VSP PF03302.13 EGR31910.1 - 5.5 5.7 56.6 0.1 11.5 1.6 3.8 3 1 1 4 4 4 0 Giardia variant-specific surface protein Ammonium_transp PF00909.21 EGR31912.1 - 2.6e-22 79.1 0.4 3e-22 78.9 0.4 1.1 1 0 0 1 1 1 1 Ammonium Transporter Family ArsP_2 PF11449.8 EGR31912.1 - 0.19 10.9 0.9 1.6 7.9 0.0 2.1 2 0 0 2 2 2 0 Putative, 10TM heavy-metal exporter Hydrolase_4 PF12146.8 EGR31913.1 - 9e-10 38.2 0.0 2.9e-08 33.3 0.0 2.2 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR31913.1 - 1.5e-06 28.0 2.4 6.7e-05 22.7 0.0 2.9 2 1 1 3 3 3 2 alpha/beta hydrolase fold FSH1 PF03959.13 EGR31913.1 - 0.019 14.6 2.5 0.022 14.4 0.0 2.3 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Peptidase_S15 PF02129.18 EGR31913.1 - 0.029 13.9 0.1 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) WD40 PF00400.32 EGR31914.1 - 3.6e-26 90.9 2.3 2.2e-05 25.1 0.3 6.5 6 0 0 6 6 6 5 WD domain, G-beta repeat Striatin PF08232.12 EGR31914.1 - 1.1e-16 61.8 21.0 2.1e-15 57.7 21.0 2.2 1 1 0 1 1 1 1 Striatin family ANAPC4_WD40 PF12894.7 EGR31914.1 - 3.6e-08 33.6 0.9 0.01 16.1 0.0 5.8 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGR31914.1 - 0.00088 18.0 2.7 0.11 11.1 0.0 3.8 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EGR31914.1 - 0.0028 16.3 0.0 0.0054 15.3 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain Acyl-CoA_dh_1 PF00441.24 EGR31915.1 - 2.5e-24 86.2 0.0 4e-24 85.5 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGR31915.1 - 8.7e-21 74.7 0.0 1.6e-20 73.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGR31915.1 - 1.7e-18 66.6 0.0 2.7e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGR31915.1 - 0.0013 19.0 0.0 0.003 17.8 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Ribosomal_L10 PF00466.20 EGR31915.1 - 0.013 15.6 0.2 0.041 14.0 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein L10 Acyl-CoA_ox_N PF14749.6 EGR31915.1 - 0.014 16.0 0.0 0.028 15.0 0.0 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Ku PF02735.16 EGR31916.1 - 1.3e-07 31.6 0.6 2.2e-07 30.8 0.6 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain UBN_AB PF14075.6 EGR31916.1 - 0.02 14.6 2.1 0.029 14.1 2.1 1.3 1 0 0 1 1 1 0 Ubinuclein conserved middle domain CSN5_C PF18323.1 EGR31916.1 - 0.079 13.9 0.6 0.26 12.2 0.6 1.9 1 1 0 1 1 1 0 Cop9 signalosome subunit 5 C-terminal domain Nuc_deoxyri_tr2 PF15891.5 EGR31916.1 - 0.13 12.6 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Nucleoside 2-deoxyribosyltransferase like DUF5406 PF17400.2 EGR31916.1 - 0.69 10.4 5.1 5.6 7.4 1.5 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5406) Pkinase PF00069.25 EGR31917.1 - 2.2e-78 263.2 0.1 3e-78 262.8 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31917.1 - 4.4e-46 157.3 0.0 6.1e-46 156.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31917.1 - 2.2e-10 40.3 0.0 5.9e-10 38.9 0.0 1.7 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGR31917.1 - 3e-06 27.0 0.6 6e-06 26.0 0.6 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGR31917.1 - 0.00011 21.6 0.2 0.00019 20.9 0.2 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGR31917.1 - 0.00029 19.9 1.2 0.00054 19.0 1.2 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGR31917.1 - 0.012 15.6 0.1 0.18 11.7 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 EGR31917.1 - 0.018 14.6 0.3 0.05 13.2 0.1 1.7 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 MFS_1 PF07690.16 EGR31918.1 - 1.7e-28 99.5 11.7 2e-27 96.1 0.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGR31918.1 - 3.5e-25 88.8 3.2 3.5e-25 88.8 3.2 2.0 1 1 1 2 2 2 2 Sugar (and other) transporter DUF1129 PF06570.11 EGR31918.1 - 9.7 5.6 9.1 2.5 7.6 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) adh_short PF00106.25 EGR31919.1 - 3.3e-08 33.2 0.0 4.2e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGR31919.1 - 0.00028 20.9 0.0 0.00037 20.4 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 EGR31919.1 - 0.0095 15.5 0.0 0.012 15.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FtsX PF02687.21 EGR31920.1 - 1.5e-15 57.4 24.5 5.8e-09 36.3 8.9 6.4 6 1 0 6 6 6 4 FtsX-like permease family WD40 PF00400.32 EGR31921.1 - 5.7e-29 99.8 7.1 1.4e-07 32.1 0.0 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR31921.1 - 1.6e-14 53.9 0.1 0.00022 21.4 0.0 5.2 1 1 5 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGR31921.1 - 5.5e-06 26.4 0.2 0.00049 20.0 0.1 2.4 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGR31921.1 - 0.00017 20.7 0.0 0.089 11.7 0.0 2.4 1 1 1 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 EGR31921.1 - 0.002 18.1 0.0 1.1 9.4 0.0 4.0 3 2 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region PALB2_WD40 PF16756.5 EGR31921.1 - 0.017 14.0 0.1 3.4 6.5 0.0 2.8 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain B_lectin PF01453.24 EGR31921.1 - 0.055 14.0 0.1 0.33 11.5 0.1 2.1 1 1 1 2 2 2 0 D-mannose binding lectin CNDH2_M PF16869.5 EGR31922.1 - 0.15 12.7 3.7 10 6.8 0.0 2.6 2 0 0 2 2 2 0 PF16858 DUF3823 PF12866.7 EGR31922.1 - 0.85 10.0 6.5 0.23 11.8 0.5 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3823) N-terminal domain DUF2615 PF11027.8 EGR31923.1 - 0.00083 19.5 0.6 0.0014 18.7 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2615) LRR_9 PF14580.6 EGR31924.1 - 3.9e-15 55.8 2.2 5.6e-15 55.3 2.2 1.2 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EGR31924.1 - 3.4e-10 40.0 11.6 0.0015 18.9 1.6 4.0 3 1 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGR31924.1 - 4.1e-07 29.7 10.4 0.007 16.1 1.4 3.6 2 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 EGR31924.1 - 0.0018 18.5 9.3 2.4 9.0 0.1 4.9 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 EGR31924.1 - 0.26 11.4 5.7 19 5.6 0.0 4.0 4 0 0 4 4 4 0 Leucine Rich repeat LRR_9 PF14580.6 EGR31925.1 - 1.3e-09 37.8 3.1 3.4e-09 36.5 3.1 1.7 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EGR31925.1 - 0.00045 20.6 2.9 0.00045 20.6 2.9 4.9 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGR31925.1 - 0.0098 15.6 4.3 0.022 14.5 2.1 2.7 1 1 0 1 1 1 1 Leucine rich repeat ACP53EA PF06313.11 EGR31925.1 - 0.14 12.3 0.7 0.62 10.3 0.2 2.4 2 0 0 2 2 2 0 Drosophila ACP53EA protein PP2C PF00481.21 EGR31926.1 - 6.4e-47 160.3 0.0 8e-47 160.0 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGR31926.1 - 5e-08 32.8 0.0 7e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGR31926.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) RL10P_insert PF17777.1 EGR31927.1 - 4.9e-23 80.9 0.1 1.2e-22 79.7 0.1 1.7 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EGR31927.1 - 7.8e-22 77.3 0.0 1.3e-21 76.6 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 EGR31927.1 - 4.5e-07 30.4 13.2 2.8e-06 27.8 13.2 2.1 1 1 0 1 1 1 1 60s Acidic ribosomal protein Fcf2 PF08698.11 EGR31928.1 - 6.6e-22 77.7 1.4 6.6e-22 77.7 1.4 1.6 2 0 0 2 2 2 1 Fcf2 pre-rRNA processing APP_amyloid PF10515.9 EGR31928.1 - 0.068 13.7 0.7 6.6 7.3 0.1 2.6 2 0 0 2 2 2 0 Beta-amyloid precursor protein C-terminus Sec61_beta PF03911.16 EGR31929.1 - 3.6e-09 36.5 1.5 5e-09 36.0 1.5 1.2 1 0 0 1 1 1 1 Sec61beta family TCP PF03634.13 EGR31930.1 - 0.011 16.3 7.6 0.013 16.0 7.6 1.2 1 0 0 1 1 1 0 TCP family transcription factor EMC3_TMCO1 PF01956.16 EGR31930.1 - 0.093 12.5 10.1 0.16 11.7 10.0 1.4 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Folliculin PF11704.8 EGR31930.1 - 0.1 12.5 4.8 0.12 12.2 4.8 1.1 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Transformer PF06495.11 EGR31930.1 - 0.27 11.3 8.3 0.32 11.1 8.3 1.1 1 0 0 1 1 1 0 Fruit fly transformer protein DUF1509 PF07420.11 EGR31930.1 - 0.29 10.0 2.6 0.37 9.7 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) DUF2828 PF11443.8 EGR31930.1 - 0.46 8.5 8.8 0.49 8.4 8.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SPC25 PF06703.11 EGR31930.1 - 0.86 9.4 6.3 1.3 8.8 6.3 1.4 1 0 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) MAP17 PF15807.5 EGR31930.1 - 1.2 9.4 6.6 1.7 8.9 6.6 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Connexin PF00029.19 EGR31930.1 - 2 8.1 10.6 3 7.6 10.6 1.3 1 1 0 1 1 1 0 Connexin Atrophin-1 PF03154.15 EGR31930.1 - 4.3 5.5 9.2 5.1 5.3 9.2 1.2 1 0 0 1 1 1 0 Atrophin-1 family Cation_efflux PF01545.21 EGR31931.1 - 3.4e-39 134.6 23.9 6.3e-39 133.8 23.9 1.4 1 1 0 1 1 1 1 Cation efflux family Zip PF02535.22 EGR31931.1 - 0.027 13.7 33.1 0.0076 15.5 29.1 1.9 1 1 1 2 2 2 0 ZIP Zinc transporter AFP_2 PF18815.1 EGR31931.1 - 0.37 11.1 2.2 0.91 9.8 2.2 1.6 1 0 0 1 1 1 0 Bacterial antifreeze protein repeat Connexin PF00029.19 EGR31931.1 - 1 9.0 7.2 8.4 6.1 7.1 2.2 1 1 0 1 1 1 0 Connexin Ribosomal_L23 PF00276.20 EGR31932.1 - 2.3e-16 59.9 4.3 2.3e-16 59.9 4.3 2.5 2 2 0 2 2 2 1 Ribosomal protein L23 Ribosomal_L23eN PF03939.13 EGR31932.1 - 2.3e-12 46.9 10.4 2.3e-12 46.9 10.4 2.9 2 1 1 3 3 3 1 Ribosomal protein L23, N-terminal domain TusA PF01206.17 EGR31932.1 - 0.0053 16.6 0.1 0.014 15.2 0.1 1.8 1 0 0 1 1 1 1 Sulfurtransferase TusA IHABP4_N PF16174.5 EGR31932.1 - 0.9 10.1 9.9 1.2 9.7 9.9 1.1 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal K_trans PF02705.16 EGR31932.1 - 2.3 6.6 4.6 0.78 8.2 1.0 1.7 1 1 1 2 2 2 0 K+ potassium transporter Utp11 PF03998.13 EGR31933.1 - 6e-46 157.4 39.8 7.5e-46 157.0 39.8 1.1 1 0 0 1 1 1 1 Utp11 protein FliP PF00813.20 EGR31933.1 - 2.6 7.9 6.3 0.22 11.4 0.6 2.0 1 1 1 2 2 2 0 FliP family NFACT-R_1 PF05670.13 EGR31934.1 - 2.2e-31 108.7 2.6 4.7e-31 107.7 0.3 2.8 2 0 0 2 2 2 1 NFACT protein RNA binding domain FF PF01846.19 EGR31934.1 - 1.7e-29 101.7 32.5 3.8e-11 43.0 2.8 6.2 7 0 0 7 7 7 4 FF domain FbpA PF05833.11 EGR31934.1 - 5.1e-21 75.0 42.3 1.2e-17 63.8 1.3 6.7 4 3 1 6 6 6 2 Fibronectin-binding protein A N-terminus (FbpA) NFACT-C PF11923.8 EGR31934.1 - 1e-16 60.7 0.0 1e-16 60.7 0.0 7.5 7 1 2 9 9 9 1 NFACT protein C-terminal domain DUF5590 PF17881.1 EGR31934.1 - 0.0066 16.5 0.0 0.037 14.1 0.0 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5590) Pkinase PF00069.25 EGR31935.1 - 3.4e-13 49.6 1.5 2.8e-08 33.4 0.1 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 EGR31935.1 - 1.4e-05 24.1 0.1 3.1e-05 22.9 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Pkinase_Tyr PF07714.17 EGR31935.1 - 0.0014 18.0 0.2 0.12 11.7 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EGR31935.1 - 0.25 11.2 0.0 0.46 10.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Dockerin_1 PF00404.18 EGR31937.1 - 9.6e-05 22.5 0.1 0.00014 21.9 0.1 1.3 1 1 0 1 1 1 1 Dockerin type I domain EF-hand_7 PF13499.6 EGR31937.1 - 0.00066 20.1 0.2 0.00074 19.9 0.2 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGR31937.1 - 0.0014 18.0 0.8 0.0014 18.0 0.8 1.8 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 EGR31937.1 - 0.0026 17.2 0.3 0.0056 16.1 0.3 1.6 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EGR31937.1 - 0.0039 17.0 1.3 0.0062 16.4 0.4 1.8 1 1 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 EGR31937.1 - 0.015 15.1 0.3 0.021 14.7 0.3 1.3 1 0 0 1 1 1 0 EF-hand domain pair Glyco_transf_20 PF00982.21 EGR31938.1 - 3.6e-39 134.7 17.6 3.6e-39 134.7 17.6 2.0 2 1 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGR31938.1 - 7.3e-33 113.6 0.9 1.1e-31 109.8 0.9 2.6 1 1 0 1 1 1 1 Trehalose-phosphatase CBM_20 PF00686.19 EGR31938.1 - 1.3e-22 79.5 1.5 2.5e-22 78.6 0.1 2.3 2 0 0 2 2 2 1 Starch binding domain DNA_topoisoIV PF00521.20 EGR31939.1 - 0.33 9.8 8.9 0.39 9.5 8.9 1.1 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A MCM PF00493.23 EGR31940.1 - 2.6e-52 177.1 0.0 3.1e-52 176.9 0.0 1.0 1 0 0 1 1 1 1 MCM P-loop domain AAA_5 PF07728.14 EGR31940.1 - 4.2e-05 23.6 0.0 5.9e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 EGR31940.1 - 0.0018 18.3 0.1 0.0028 17.7 0.1 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Mg_chelatase PF01078.21 EGR31940.1 - 0.011 15.2 0.0 0.8 9.0 0.0 2.1 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EGR31940.1 - 0.016 14.9 0.1 2.1 8.0 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain Spore_IV_A PF09547.10 EGR31940.1 - 0.071 12.0 0.0 0.092 11.7 0.0 1.2 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) AAA_7 PF12775.7 EGR31940.1 - 0.15 11.6 0.0 0.21 11.1 0.0 1.4 1 1 0 1 1 1 0 P-loop containing dynein motor region TraB PF01963.17 EGR31941.1 - 0.00014 21.8 0.0 0.0019 18.2 0.0 2.2 1 1 0 1 1 1 1 TraB family CAP PF00188.26 EGR31942.1 - 5.6e-10 40.1 0.0 8.1e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Fmp27_SW PF10305.9 EGR31943.1 - 1.4 9.6 10.6 0.88 10.3 2.0 3.9 4 0 0 4 4 4 0 RNA pol II promoter Fmp27 protein domain Band_7 PF01145.25 EGR31944.1 - 2.6e-18 66.6 2.1 3.6e-18 66.2 0.0 2.0 2 0 0 2 2 2 1 SPFH domain / Band 7 family WD40_3 PF15911.5 EGR31945.1 - 3.4e-19 68.6 0.0 9.1e-19 67.2 0.0 1.8 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR31945.1 - 3.8e-05 23.9 0.0 0.0017 18.6 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 EGR31945.1 - 5.8e-05 22.9 18.6 0.89 9.8 0.1 7.8 7 0 0 7 7 6 2 Tetratricopeptide repeat Clathrin PF00637.20 EGR31945.1 - 0.00013 21.9 0.2 0.00013 21.9 0.2 5.1 2 2 4 6 6 6 1 Region in Clathrin and VPS TPR_7 PF13176.6 EGR31945.1 - 0.007 16.3 7.6 6.6 7.0 0.0 6.4 6 0 0 6 6 6 1 Tetratricopeptide repeat MIT PF04212.18 EGR31945.1 - 0.0088 16.1 11.6 1.1 9.4 0.3 4.7 4 0 0 4 4 4 2 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 EGR31945.1 - 0.013 15.8 14.7 9.9 6.5 0.0 7.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGR31945.1 - 0.033 15.0 3.7 33 5.7 0.0 4.8 5 0 0 5 5 4 0 Tetratricopeptide repeat DZR PF12773.7 EGR31945.1 - 0.18 11.8 10.6 2.4 8.3 1.1 2.5 1 1 1 2 2 2 0 Double zinc ribbon TPR_3 PF07720.12 EGR31945.1 - 0.2 11.7 8.7 2.4 8.2 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGR31945.1 - 0.26 11.2 19.9 6.3 6.8 0.1 7.1 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGR31945.1 - 0.66 10.3 18.3 30 5.2 1.1 7.7 7 1 1 8 8 7 0 Tetratricopeptide repeat zf-4CXXC_R1 PF10497.9 EGR31945.1 - 0.8 10.0 8.5 2.5 8.4 8.5 1.9 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 TPR_10 PF13374.6 EGR31945.1 - 2.7 8.0 7.4 13 5.8 0.2 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1659 PF07872.11 EGR31949.1 - 0.0039 16.8 0.5 0.009 15.6 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1659) DUF4858 PF16150.5 EGR31949.1 - 0.03 14.4 4.0 0.038 14.0 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4858) RrnaAD PF00398.20 EGR31950.1 - 0.0023 17.1 0.4 0.0037 16.4 0.4 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Ribophorin_I PF04597.14 EGR31951.1 - 5.7e-106 355.3 12.5 7.4e-106 355.0 12.5 1.0 1 0 0 1 1 1 1 Ribophorin I CAP PF00188.26 EGR31951.1 - 1.8e-11 45.0 0.9 1.4e-10 42.1 0.1 2.5 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Tropomyosin_1 PF12718.7 EGR31953.1 - 0.0091 16.2 17.9 0.0091 16.2 17.9 11.0 2 2 8 11 11 11 4 Tropomyosin like Sugar_tr PF00083.24 EGR31954.1 - 6.2e-27 94.6 28.3 8.2e-27 94.2 28.3 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGR31954.1 - 3.9e-24 85.2 25.0 5.5e-24 84.8 18.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EGR31954.1 - 1.7e-06 27.6 0.3 3.3e-06 26.6 0.3 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB PP2C PF00481.21 EGR31955.1 - 1.5e-44 152.5 0.0 2.1e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C DUF1593 PF07632.11 EGR31955.1 - 0.019 14.4 0.2 0.031 13.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1593) DUF4518 PF15008.6 EGR31955.1 - 0.04 13.1 0.1 0.066 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Peptidase_C2 PF00648.21 EGR31956.1 - 4.6e-71 239.3 0.6 4.6e-71 239.3 0.6 1.9 2 0 0 2 2 2 1 Calpain family cysteine protease Brix PF04427.18 EGR31956.1 - 1.6e-25 90.3 14.3 1.6e-25 90.3 14.3 2.2 1 1 1 2 2 2 1 Brix domain PAS PF00989.25 EGR31957.1 - 0.047 13.7 0.0 0.19 11.7 0.0 2.1 1 0 0 1 1 1 0 PAS fold CCDC53 PF10152.9 EGR31958.1 - 1.4e-09 38.5 9.0 1.6e-09 38.3 9.0 1.3 1 1 0 1 1 1 1 Subunit CCDC53 of WASH complex HMG14_17 PF01101.18 EGR31958.1 - 0.092 13.7 6.0 0.16 12.9 6.0 1.3 1 0 0 1 1 1 0 HMG14 and HMG17 MORN PF02493.20 EGR31959.1 - 5.9e-29 98.2 41.2 2e-07 30.5 1.4 7.9 8 0 0 8 8 8 6 MORN repeat Esterase PF00756.20 EGR31960.1 - 7.5e-44 150.2 0.0 1.1e-43 149.8 0.0 1.2 1 0 0 1 1 1 1 Putative esterase ADH_zinc_N PF00107.26 EGR31960.1 - 1.3e-18 67.2 0.0 2.8e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGR31960.1 - 5.2e-18 64.9 1.1 1.5e-17 63.5 1.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Peptidase_S9 PF00326.21 EGR31960.1 - 3.9e-06 26.5 0.0 6.2e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGR31960.1 - 0.01 15.1 0.0 0.038 13.2 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EGR31960.1 - 0.017 14.0 0.0 0.034 13.1 0.0 1.5 1 0 0 1 1 1 0 Chlorophyllase enzyme DNA_topoisoIV PF00521.20 EGR31961.1 - 1.8e-128 429.1 11.0 1.8e-128 429.1 11.0 4.3 3 1 2 5 5 5 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EGR31961.1 - 3.1e-47 160.0 8.7 3.1e-47 160.0 8.7 7.2 5 1 2 8 8 8 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EGR31961.1 - 3.8e-25 88.4 5.1 3.8e-25 88.4 5.1 3.6 3 0 0 3 3 3 1 DNA gyrase B HATPase_c PF02518.26 EGR31961.1 - 1.3e-09 38.5 0.1 1e-08 35.7 0.0 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EGR31961.1 - 2.7e-06 27.5 0.0 2.7e-06 27.5 0.0 3.6 2 1 0 2 2 2 1 Toprim domain AAA PF00004.29 EGR31962.1 - 8.6e-17 61.8 0.0 1.7e-16 60.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EGR31962.1 - 2.4e-14 53.4 0.0 2e-11 43.9 0.0 2.6 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 EGR31962.1 - 4e-12 46.4 0.6 1.1e-11 45.0 0.6 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.15 EGR31962.1 - 2.9e-08 33.8 1.2 1.1e-07 32.0 0.0 2.5 2 2 0 2 2 2 1 Rad17 P-loop domain AAA_11 PF13086.6 EGR31962.1 - 4.6e-06 26.6 0.1 2.7e-05 24.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGR31962.1 - 3.9e-05 23.7 0.0 0.00011 22.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGR31962.1 - 0.00011 22.4 0.2 0.062 13.6 0.2 2.5 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EGR31962.1 - 0.00016 21.7 0.1 0.011 15.8 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit AAA_5 PF07728.14 EGR31962.1 - 0.00029 20.8 0.0 0.00081 19.4 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EGR31962.1 - 0.0003 20.6 0.0 0.00051 19.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGR31962.1 - 0.0004 20.2 0.0 0.00094 19.0 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_assoc_2 PF16193.5 EGR31962.1 - 0.00048 20.4 0.0 0.0013 19.0 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_16 PF13191.6 EGR31962.1 - 0.0005 20.5 0.0 0.0018 18.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 EGR31962.1 - 0.00055 19.2 0.0 0.00097 18.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_19 PF13245.6 EGR31962.1 - 0.00059 20.2 0.1 0.0065 16.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGR31962.1 - 0.00068 19.2 0.0 0.0015 18.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region RuvB_N PF05496.12 EGR31962.1 - 0.00093 19.0 0.0 0.002 17.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EGR31962.1 - 0.0014 18.3 0.0 0.0038 17.0 0.0 1.8 1 1 0 1 1 1 1 IstB-like ATP binding protein Viral_helicase1 PF01443.18 EGR31962.1 - 0.0098 15.7 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase RNA_helicase PF00910.22 EGR31962.1 - 0.01 16.2 0.0 0.027 14.8 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_3 PF07726.11 EGR31962.1 - 0.014 15.3 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGR31962.1 - 0.014 15.9 0.0 0.035 14.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGR31962.1 - 0.026 13.9 0.0 0.19 11.1 0.0 2.0 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI DEAD PF00270.29 EGR31962.1 - 0.028 14.2 0.2 0.44 10.3 0.0 2.2 1 1 0 2 2 2 0 DEAD/DEAH box helicase TniB PF05621.11 EGR31962.1 - 0.04 13.3 0.1 1.2 8.6 0.0 2.4 1 1 1 2 2 2 0 Bacterial TniB protein SRP54 PF00448.22 EGR31962.1 - 0.05 13.2 0.1 0.09 12.4 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SNF2_N PF00176.23 EGR31962.1 - 0.051 12.3 0.3 0.38 9.4 0.2 2.4 1 1 1 2 2 2 0 SNF2 family N-terminal domain DUF2075 PF09848.9 EGR31962.1 - 0.066 12.5 0.2 0.21 10.8 0.2 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 EGR31962.1 - 0.13 11.3 0.0 0.25 10.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_23 PF13476.6 EGR31962.1 - 0.16 12.5 4.0 0.23 11.9 3.1 1.8 1 1 0 1 1 1 0 AAA domain ARL2_Bind_BART PF11527.8 EGR31963.1 - 1.5e-39 134.7 9.4 1.5e-39 134.7 9.4 3.0 2 0 0 2 2 2 1 The ARF-like 2 binding protein BART Ank_2 PF12796.7 EGR31963.1 - 4.9e-16 59.1 0.5 2.1e-08 34.6 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGR31963.1 - 5.6e-13 49.1 0.0 2.5e-07 31.1 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGR31963.1 - 6.8e-10 39.0 0.1 2.4e-06 27.7 0.0 3.5 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGR31963.1 - 1.1e-08 35.1 0.0 0.0011 19.3 0.0 4.4 4 0 0 4 4 4 2 Ankyrin repeat WD40 PF00400.32 EGR31963.1 - 9.4e-08 32.6 0.6 0.095 13.6 0.0 3.7 3 0 0 3 3 3 2 WD domain, G-beta repeat Ank_3 PF13606.6 EGR31963.1 - 1.7e-06 27.9 0.0 0.016 15.7 0.0 4.7 4 1 0 4 4 4 1 Ankyrin repeat ANAPC4_WD40 PF12894.7 EGR31963.1 - 0.07 13.4 0.4 1.6 9.1 0.1 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain MFS_1 PF07690.16 EGR31964.1 - 7.4e-33 113.9 17.3 7.4e-33 113.9 17.3 1.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGR31964.1 - 1.2e-06 27.7 1.5 1.2e-06 27.7 1.5 3.2 2 1 1 3 3 3 1 Sugar (and other) transporter DUF5383 PF17355.2 EGR31964.1 - 0.071 13.5 0.2 0.071 13.5 0.2 2.8 3 0 0 3 3 3 0 Family of unknown function (DUF5383) MFS_3 PF05977.13 EGR31964.1 - 0.3 9.4 3.3 0.35 9.2 0.1 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Shisa PF13908.6 EGR31965.1 - 0.08 13.2 5.6 0.41 10.9 5.6 2.1 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator PROCT PF08084.11 EGR31966.1 - 0.0099 15.8 0.7 0.012 15.5 0.7 1.2 1 0 0 1 1 1 1 PROCT (NUC072) domain EMC3_TMCO1 PF01956.16 EGR31966.1 - 1.2 8.9 17.1 1.4 8.7 17.1 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like XPA_C PF05181.12 EGR31967.1 - 0.065 13.2 0.2 0.17 11.9 0.2 1.7 1 0 0 1 1 1 0 XPA protein C-terminus POTRA_TamA_1 PF17243.2 EGR31967.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 POTRA domain TamA domain 1 2-oxoacid_dh PF00198.23 EGR31968.1 - 1.1e-68 231.2 0.6 1.3e-68 231.0 0.6 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Nitroreductase PF00881.24 EGR31970.1 - 9.6e-21 74.6 0.0 1.1e-20 74.3 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family TM1586_NiRdase PF14512.6 EGR31970.1 - 1.1e-05 25.1 0.6 0.014 15.0 0.0 2.8 2 1 1 3 3 3 2 Putative TM nitroreductase DUF787 PF05619.11 EGR31970.1 - 0.031 13.4 0.0 0.041 13.0 0.0 1.1 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF787) Vma12 PF11712.8 EGR31970.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Rubis-subs-bind PF09273.11 EGR31971.1 - 2.2e-05 25.2 0.0 2.2e-05 25.2 0.0 2.6 2 1 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.28 EGR31971.1 - 0.00012 22.5 1.7 0.00012 22.5 1.7 3.9 1 1 1 2 2 2 1 SET domain Mem_trans PF03547.18 EGR31971.1 - 0.24 9.8 1.1 0.36 9.2 1.1 1.4 1 0 0 1 1 1 0 Membrane transport protein Dapper PF15268.6 EGR31971.1 - 5.8 5.6 22.1 8 5.2 22.1 1.2 1 0 0 1 1 1 0 Dapper CcdB PF01845.17 EGR31972.1 - 0.014 15.6 0.5 0.035 14.3 0.5 1.7 1 0 0 1 1 1 0 CcdB protein DUF3519 PF12033.8 EGR31972.1 - 0.78 10.2 9.2 9.2 6.7 9.1 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3519) CH PF00307.31 EGR31973.1 - 4.5e-17 62.2 2.0 1.1e-14 54.5 0.3 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGR31973.1 - 0.037 13.9 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 CAMSAP CH domain CH PF00307.31 EGR31974.1 - 2.3e-48 162.9 17.8 3.2e-22 78.8 0.8 4.2 3 1 1 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGR31974.1 - 9.4e-08 31.8 1.3 0.00083 19.1 0.1 2.7 2 0 0 2 2 2 2 CAMSAP CH domain CH_2 PF06294.11 EGR31974.1 - 0.031 14.4 3.7 0.23 11.6 0.0 3.4 4 0 0 4 4 4 0 CH-like domain in sperm protein IBR PF01485.21 EGR31975.1 - 1.4e-20 73.2 43.2 4.1e-13 49.3 4.6 4.2 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EGR31975.1 - 3.4e-07 30.0 42.8 7e-06 25.8 8.4 4.5 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGR31975.1 - 8.8e-07 29.2 38.3 1.9e-05 24.9 6.9 3.5 3 0 0 3 3 3 2 Ring finger domain zf-RING_UBOX PF13445.6 EGR31975.1 - 0.00018 21.4 27.8 0.00067 19.6 6.1 3.0 2 0 0 2 2 2 2 RING-type zinc-finger zf-RING_5 PF14634.6 EGR31975.1 - 0.00024 21.0 10.2 0.00024 21.0 10.2 3.9 3 1 0 3 3 3 2 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGR31975.1 - 0.00045 20.0 4.9 0.00045 20.0 4.9 4.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 EGR31975.1 - 0.0013 18.5 5.1 0.0013 18.5 5.1 3.4 2 2 1 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 EGR31975.1 - 0.37 11.0 38.3 0.17 12.1 6.3 5.0 3 2 1 4 4 4 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGR31975.1 - 0.64 9.8 33.2 0.72 9.7 7.9 3.8 3 1 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 EGR31975.1 - 7.2 6.5 25.0 0.58 10.0 7.3 3.1 2 1 0 2 2 2 0 RING-like zinc finger Pkinase PF00069.25 EGR31976.1 - 1.9e-64 217.6 0.6 4.2e-64 216.4 0.6 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31976.1 - 1.8e-42 145.4 0.2 1.8e-42 145.4 0.2 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR31976.1 - 5.3e-07 29.3 0.2 2.6e-06 26.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like NOP5NT PF08156.13 EGR31976.1 - 0.31 11.5 1.9 1.2 9.6 1.9 2.0 1 0 0 1 1 1 0 NOP5NT (NUC127) domain LacAB_rpiB PF02502.18 EGR31978.1 - 2.1e-48 163.9 0.6 2.3e-48 163.7 0.6 1.0 1 0 0 1 1 1 1 Ribose/Galactose Isomerase TTL PF03133.15 EGR31979.1 - 7.8e-54 182.8 12.5 1.5e-53 181.9 12.5 1.4 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR31979.1 - 3.5e-08 33.0 0.1 3e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR31979.1 - 0.0054 16.0 0.9 0.025 13.8 0.0 2.4 2 1 0 2 2 2 1 Sugar-transfer associated ATP-grasp Penicil_amidase PF01804.18 EGR31980.1 - 4.9e-76 257.1 2.4 5.4e-56 190.9 0.0 2.0 1 1 1 2 2 2 2 Penicillin amidase Penicil_amidase PF01804.18 EGR31981.1 - 6.9e-37 127.8 0.0 7.4e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Penicillin amidase adh_short PF00106.25 EGR31982.1 - 3.2e-36 124.6 0.1 3.8e-31 108.1 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGR31982.1 - 3.1e-22 79.3 0.0 2.4e-21 76.4 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGR31982.1 - 3.2e-08 33.7 0.0 5.9e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGR31982.1 - 0.0055 16.2 0.0 0.0092 15.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GPI2 PF06432.11 EGR31982.1 - 6.5 6.1 13.1 0.21 11.0 3.2 2.2 1 1 0 2 2 2 0 Phosphatidylinositol N-acetylglucosaminyltransferase LRR_4 PF12799.7 EGR31983.1 - 3.2e-16 59.2 35.7 0.00034 20.9 3.6 5.8 4 2 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGR31983.1 - 4.6e-14 51.9 25.1 5.7e-07 29.2 0.5 5.2 2 1 4 6 6 6 6 Leucine rich repeat LRR_9 PF14580.6 EGR31983.1 - 1.6e-07 31.0 18.6 0.0022 17.5 2.6 3.3 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 EGR31983.1 - 0.00025 20.9 18.4 0.047 13.8 0.1 7.1 7 1 0 8 8 8 2 Leucine Rich repeat PUB PF09409.10 EGR31984.1 - 1.5e-08 34.5 1.7 1.5e-08 34.5 1.7 2.2 2 0 0 2 2 2 1 PUB domain UBX PF00789.20 EGR31984.1 - 7e-07 29.4 0.0 2.1e-06 27.8 0.0 1.8 1 0 0 1 1 1 1 UBX domain DUF4136 PF13590.6 EGR31984.1 - 0.0044 17.6 1.4 0.034 14.7 0.4 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4136) DUF2340 PF10209.9 EGR31984.1 - 1.7 9.1 8.3 2.9 8.3 2.1 3.2 3 1 0 3 3 3 0 Uncharacterized conserved protein (DUF2340) Pkinase PF00069.25 EGR31985.1 - 3.8e-52 177.3 1.3 6e-52 176.6 1.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR31985.1 - 3e-25 89.0 0.1 5.3e-25 88.2 0.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR31985.1 - 0.0087 14.9 0.1 0.012 14.4 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Cullin_Nedd8 PF10557.9 EGR31985.1 - 0.062 13.3 1.9 0.17 11.9 0.4 2.4 2 0 0 2 2 2 0 Cullin protein neddylation domain Kinase-like PF14531.6 EGR31985.1 - 0.072 12.4 0.0 0.18 11.1 0.0 1.6 2 0 0 2 2 2 0 Kinase-like UDPGP PF01704.18 EGR31986.1 - 1.1e-14 53.9 6.5 1.9e-14 53.2 6.5 1.3 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase TetR_N PF00440.23 EGR31986.1 - 0.051 13.4 0.0 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family ATP-synt_ab_Xtn PF16886.5 EGR31987.1 - 5.8e-45 152.1 0.0 9.7e-45 151.3 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EGR31987.1 - 3.8e-14 53.0 0.1 6.9e-14 52.1 0.1 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain ATP-synt_ab PF00006.25 EGR31987.1 - 1.1e-07 31.7 0.0 1.7e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab PF00006.25 EGR31988.1 - 1.2e-75 253.8 0.0 1.3e-75 253.7 0.0 1.0 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Crp PF00325.20 EGR31989.1 - 0.13 11.9 0.0 0.29 10.8 0.0 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family Sugar_tr PF00083.24 EGR31990.1 - 2.8e-18 66.0 10.3 2.8e-18 66.0 10.3 1.9 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 EGR31990.1 - 1.4e-08 34.0 5.5 1.4e-08 34.0 5.5 2.8 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF1512 PF07431.12 EGR31990.1 - 0.099 11.6 0.0 0.099 11.6 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1512) Ion_trans PF00520.31 EGR31992.1 - 5.8e-14 51.9 13.4 1.1e-13 51.0 13.4 1.4 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 EGR31992.1 - 6.9e-14 51.6 7.4 6.9e-14 51.6 7.4 2.0 1 1 1 2 2 2 1 Ion channel cNMP_binding PF00027.29 EGR31992.1 - 1.1e-08 35.0 0.0 2.1e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain AhpC-TSA PF00578.21 EGR31994.1 - 1.8e-36 124.8 0.0 2.5e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGR31994.1 - 2.1e-19 69.7 0.0 3.4e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EGR31994.1 - 2e-15 56.3 2.5 3.5e-15 55.6 1.0 2.0 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 EGR31994.1 - 0.18 11.7 0.1 0.5 10.3 0.1 1.7 2 0 0 2 2 2 0 SCO1/SenC zf-RING_2 PF13639.6 EGR31995.1 - 1.1e-08 35.2 5.1 2.6e-08 34.1 5.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGR31995.1 - 7.6e-06 25.7 6.9 1.7e-05 24.6 6.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGR31995.1 - 2e-05 24.3 4.8 3.8e-05 23.5 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGR31995.1 - 2.5e-05 24.0 6.3 5.3e-05 23.0 6.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGR31995.1 - 4.9e-05 23.0 4.9 0.00017 21.3 4.9 2.0 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 EGR31995.1 - 0.00055 19.8 6.8 0.0013 18.6 6.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGR31995.1 - 0.001 19.0 5.9 0.0029 17.6 5.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGR31995.1 - 0.0061 16.4 4.4 0.011 15.5 4.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGR31995.1 - 0.013 15.6 3.4 0.047 13.8 3.4 2.0 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGR31995.1 - 0.028 14.7 5.4 0.096 13.0 5.4 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger domain Zf_RING PF16744.5 EGR31995.1 - 0.14 12.3 1.8 0.31 11.2 1.6 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 EGR31995.1 - 0.46 10.2 2.5 0.97 9.1 2.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 EGR31995.1 - 0.53 10.6 5.3 1 9.7 5.3 1.5 1 0 0 1 1 1 0 RING-like domain Prok-RING_1 PF14446.6 EGR31995.1 - 0.75 9.8 4.8 2 8.4 0.8 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 PHD PF00628.29 EGR31995.1 - 0.81 9.6 4.5 1.7 8.6 4.5 1.6 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 EGR31995.1 - 3.6 7.4 7.0 94 2.9 7.0 2.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Topoisom_bac PF01131.20 EGR31996.1 - 3.1e-23 82.5 0.8 3.1e-23 82.5 0.8 1.9 1 1 1 2 2 2 1 DNA topoisomerase Toprim PF01751.22 EGR31996.1 - 2.8e-18 66.0 1.0 6.2e-18 64.9 0.1 2.1 2 0 0 2 2 2 1 Toprim domain Toprim_4 PF13662.6 EGR31996.1 - 0.071 13.6 0.0 0.22 12.0 0.0 1.9 1 0 0 1 1 1 0 Toprim domain Ribosomal_L4 PF00573.22 EGR31997.1 - 7.2e-43 146.5 1.7 9.4e-43 146.1 1.7 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family WD40 PF00400.32 EGR31998.1 - 1.2e-23 82.9 6.9 4.7e-05 24.1 0.0 6.4 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR31998.1 - 1.2e-12 47.9 1.8 0.0001 22.6 0.3 4.0 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain MRP-S33 PF08293.11 EGR31998.1 - 0.019 15.2 4.6 0.19 12.0 0.7 2.8 2 0 0 2 2 2 0 Mitochondrial ribosomal subunit S27 Sugar_tr PF00083.24 EGR32000.1 - 1.1e-69 235.5 21.2 1.2e-69 235.3 21.2 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGR32000.1 - 5.8e-17 61.6 11.4 4.5e-16 58.7 8.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily UPF0004 PF00919.20 EGR32000.1 - 0.085 12.9 0.1 0.17 12.0 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized protein family UPF0004 TssO PF17561.2 EGR32000.1 - 0.39 10.8 9.3 7.4 6.7 4.3 2.6 2 0 0 2 2 2 0 Type VI secretion system, TssO DER1 PF04511.15 EGR32001.1 - 8.7e-35 120.4 14.3 1.1e-34 120.0 14.3 1.1 1 0 0 1 1 1 1 Der1-like family Bromodomain PF00439.25 EGR32002.1 - 1.1e-20 73.5 7.0 1.1e-20 73.5 7.0 2.4 3 0 0 3 3 3 1 Bromodomain BET PF17035.5 EGR32002.1 - 2.8e-17 62.7 0.6 2.8e-17 62.7 0.6 3.2 3 0 0 3 3 3 1 Bromodomain extra-terminal - transcription regulation Peptidase_M4 PF01447.18 EGR32002.1 - 0.0034 17.9 2.6 0.0052 17.3 2.6 1.3 1 0 0 1 1 1 1 Thermolysin metallopeptidase, catalytic domain T3SSipB PF16535.5 EGR32002.1 - 0.065 13.7 0.5 0.13 12.7 0.5 1.5 1 0 0 1 1 1 0 Type III cell invasion protein SipB DUF4337 PF14235.6 EGR32002.1 - 5.3 7.1 11.9 0.99 9.5 2.0 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4337) DUF3970 PF13113.6 EGR32003.1 - 4.4 7.6 8.3 0.53 10.5 1.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3970) TPP_enzyme_N PF02776.18 EGR32004.1 - 3.8e-23 82.0 0.0 2.3e-22 79.4 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EGR32004.1 - 5.9e-16 58.6 1.6 4.7e-15 55.7 0.6 2.6 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Cys_rich_KTR PF14205.6 EGR32006.1 - 0.27 11.0 2.0 1.9 8.3 0.3 2.5 2 0 0 2 2 2 0 Cysteine-rich KTR DUF4200 PF13863.6 EGR32008.1 - 4.5e-27 94.8 37.0 4.5e-27 94.8 37.0 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF4200) DUF3584 PF12128.8 EGR32008.1 - 0.074 10.6 37.1 0.098 10.2 37.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) DUF3138 PF11336.8 EGR32008.1 - 0.11 11.1 0.3 0.15 10.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) SLED PF12140.8 EGR32008.1 - 0.75 10.3 14.9 0.24 11.9 1.6 2.6 3 0 0 3 3 3 0 SLED domain Spc7 PF08317.11 EGR32008.1 - 1.2 7.9 53.2 0.33 9.8 22.3 3.0 1 1 2 3 3 3 0 Spc7 kinetochore protein Pkinase PF00069.25 EGR32009.1 - 6.1e-65 219.2 0.0 6.1e-65 219.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32009.1 - 1.5e-33 116.2 1.3 2e-33 115.8 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_2 PF12796.7 EGR32009.1 - 5.5e-21 74.9 3.6 7.7e-15 55.3 1.5 3.0 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGR32009.1 - 2.1e-16 59.8 2.3 2.2e-08 34.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGR32009.1 - 1.4e-15 57.4 0.5 5.9e-07 29.9 0.1 3.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR32009.1 - 1.3e-13 49.7 3.4 0.0025 18.2 0.2 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EGR32009.1 - 3.9e-11 42.9 6.1 0.0043 17.5 1.2 4.2 4 0 0 4 4 4 3 Ankyrin repeat Kinase-like PF14531.6 EGR32009.1 - 6.1e-05 22.5 0.0 6.1e-05 22.5 0.0 2.0 2 0 0 2 2 1 1 Kinase-like Kdo PF06293.14 EGR32009.1 - 0.0034 16.8 0.0 0.0034 16.8 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family TFIIA PF03153.13 EGR32009.1 - 0.0056 16.7 18.8 0.0081 16.2 18.8 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 EGR32009.1 - 0.0069 16.4 8.6 0.012 15.6 8.6 1.4 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) rhaM PF05336.13 EGR32009.1 - 0.0091 16.0 1.9 0.039 14.0 1.9 2.0 1 0 0 1 1 1 1 L-rhamnose mutarotase Roughex PF06020.11 EGR32009.1 - 0.43 9.6 3.5 0.63 9.1 3.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein OmpH PF03938.14 EGR32009.1 - 4.5 7.6 28.4 15 5.9 0.4 2.4 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Ank_2 PF12796.7 EGR32010.1 - 4.5e-33 113.7 1.1 1.5e-10 41.6 0.1 3.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGR32010.1 - 6.5e-29 99.9 2.3 1.7e-10 41.2 0.1 6.1 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR32010.1 - 6.4e-26 87.6 0.0 0.0076 16.7 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EGR32010.1 - 1.2e-24 86.0 0.0 8.8e-05 22.7 0.0 6.9 2 1 5 7 7 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EGR32010.1 - 4.4e-17 61.7 0.1 0.11 13.0 0.0 6.6 7 0 0 7 7 6 4 Ankyrin repeat TPR_1 PF00515.28 EGR32010.1 - 3.2e-09 36.2 16.4 0.00012 21.8 2.2 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGR32010.1 - 3e-06 26.9 15.0 0.0032 17.5 1.5 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGR32010.1 - 4.1e-06 26.6 7.8 0.028 14.6 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGR32010.1 - 3.5e-05 23.4 5.6 0.0013 18.4 2.4 2.7 2 0 0 2 2 2 1 TPR repeat ANAPC3 PF12895.7 EGR32010.1 - 0.00051 20.2 5.0 0.00051 20.2 5.0 2.5 2 1 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EGR32010.1 - 0.0013 19.0 2.7 0.023 15.0 1.1 2.7 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGR32010.1 - 0.0082 16.0 1.0 0.52 10.3 0.3 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGR32010.1 - 0.012 15.6 0.7 2.5 8.3 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EGR32010.1 - 0.023 14.7 2.1 0.023 14.7 2.1 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain PRANC PF09372.10 EGR32010.1 - 0.056 13.8 8.2 0.069 13.5 1.4 3.4 3 1 0 3 3 3 0 PRANC domain TPR_14 PF13428.6 EGR32010.1 - 0.068 14.0 0.1 4.4 8.4 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGR32010.1 - 1.7 9.2 6.6 5 7.7 1.7 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat CxC1 PF18802.1 EGR32011.1 - 0.0057 16.8 0.7 0.0083 16.3 0.6 1.4 1 1 0 1 1 1 1 CxC1 like cysteine cluster associated with KDZ transposases BUD22 PF09073.10 EGR32012.1 - 0.024 14.0 43.2 0.03 13.7 43.2 1.1 1 0 0 1 1 1 0 BUD22 DUF4045 PF13254.6 EGR32012.1 - 2.8 7.5 23.3 3.7 7.1 23.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Hid1 PF12722.7 EGR32012.1 - 3.9 5.5 24.1 5.2 5.1 24.1 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pkinase PF00069.25 EGR32013.1 - 2.6e-72 243.4 0.4 2.6e-72 243.4 0.4 3.0 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32013.1 - 9.5e-34 116.8 0.1 9.5e-34 116.8 0.1 2.5 3 0 0 3 3 3 1 Protein tyrosine kinase APH PF01636.23 EGR32013.1 - 0.046 13.6 2.4 0.25 11.2 0.0 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family RabGAP-TBC PF00566.18 EGR32014.1 - 9e-16 58.2 6.3 1.1e-15 57.8 6.3 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Spore_YabQ PF09578.10 EGR32014.1 - 0.21 11.8 1.8 0.45 10.8 1.8 1.6 1 1 0 1 1 1 0 Spore cortex protein YabQ (Spore_YabQ) WD40 PF00400.32 EGR32015.1 - 5.4e-10 39.7 0.2 0.00064 20.5 0.1 5.2 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR32015.1 - 0.017 15.4 0.3 1.1 9.6 0.1 3.2 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain LRR_4 PF12799.7 EGR32015.1 - 1.2 9.7 17.5 9.8 6.8 0.2 5.9 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) WD40 PF00400.32 EGR32016.1 - 1.2e-25 89.2 3.8 1e-07 32.5 0.0 6.6 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR32016.1 - 3.9e-19 68.8 1.8 5.8e-07 29.7 0.0 4.5 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGR32016.1 - 2.1e-06 27.8 11.3 0.018 15.0 0.2 3.7 2 1 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGR32016.1 - 2.9e-05 23.2 0.7 0.016 14.2 0.0 2.8 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 EGR32016.1 - 0.018 14.4 0.6 0.075 12.3 0.6 2.0 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Pkinase PF00069.25 EGR32017.1 - 5.3e-66 222.7 3.0 5.3e-66 222.7 3.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32017.1 - 6.8e-31 107.5 0.2 1.1e-30 106.8 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR32017.1 - 1.9e-06 27.4 0.2 5.7e-06 25.8 0.1 1.9 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR32017.1 - 2.5e-06 26.5 0.6 6e-06 25.3 0.1 1.9 1 1 1 2 2 2 1 Fungal protein kinase APH PF01636.23 EGR32017.1 - 0.0065 16.4 0.0 0.013 15.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family A_deaminase PF00962.22 EGR32018.1 - 2.6e-95 319.5 0.0 3.4e-95 319.1 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase MFS_1 PF07690.16 EGR32020.1 - 1.3e-22 80.2 26.3 6.7e-22 77.9 24.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1772 PF08592.11 EGR32020.1 - 0.071 13.4 1.4 0.72 10.2 0.0 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) CD36 PF01130.21 EGR32021.1 - 1.5e-17 63.3 18.3 9.9e-10 37.5 1.0 3.3 2 1 1 3 3 3 3 CD36 family Urotensin_II PF02083.15 EGR32021.1 - 1.5 8.6 4.4 3.5 7.5 4.4 1.6 1 0 0 1 1 1 0 Urotensin II Radial_spoke_3 PF06098.11 EGR32022.1 - 3.7e-88 295.5 20.6 3.7e-88 295.5 20.6 1.8 2 0 0 2 2 2 1 Radial spoke protein 3 Adap_comp_sub PF00928.21 EGR32023.1 - 1.9e-79 266.7 1.0 1.9e-79 266.7 0.3 1.4 2 0 0 2 2 2 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGR32023.1 - 1.5 8.7 8.1 0.45 10.4 3.8 2.0 2 0 0 2 2 2 0 Clathrin adaptor complex small chain Furin-like_2 PF15913.5 EGR32024.1 - 0.0073 16.4 10.2 0.0073 16.4 10.2 6.1 1 1 5 6 6 6 3 Furin-like repeat, cysteine-rich VSP PF03302.13 EGR32024.1 - 1 8.1 71.7 0.57 9.0 23.2 3.7 1 1 2 3 3 3 0 Giardia variant-specific surface protein Mob1_phocein PF03637.17 EGR32025.1 - 8.1e-30 104.1 0.4 1e-29 103.7 0.4 1.1 1 0 0 1 1 1 1 Mob1/phocein family LSR PF05624.14 EGR32025.1 - 0.0044 17.0 0.3 0.008 16.2 0.3 1.3 1 0 0 1 1 1 1 Lipolysis stimulated receptor (LSR) Lsm_C PF14894.6 EGR32025.1 - 0.17 11.7 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 Lsm C-terminal TLD PF07534.16 EGR32026.1 - 8.9e-18 64.8 3.3 2.7e-17 63.3 3.3 1.9 1 0 0 1 1 1 1 TLD Globin PF00042.22 EGR32026.1 - 0.0098 16.4 1.0 0.12 12.9 0.2 2.4 2 0 0 2 2 2 1 Globin Kinesin PF00225.23 EGR32029.1 - 3.7e-91 305.5 7.8 3.7e-91 305.5 7.8 4.3 3 1 2 5 5 5 1 Kinesin motor domain Microtub_bd PF16796.5 EGR32029.1 - 8.3e-11 42.0 2.0 8.3e-11 42.0 2.0 5.4 2 2 3 5 5 5 2 Microtubule binding DUF948 PF06103.11 EGR32029.1 - 0.22 11.8 1.6 0.51 10.6 0.2 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Pkinase PF00069.25 EGR32030.1 - 2e-52 178.1 6.9 1.8e-51 175.0 0.6 3.0 2 2 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32030.1 - 2.6e-23 82.6 0.4 8.9e-17 61.2 0.0 2.6 2 1 1 3 3 3 2 Protein tyrosine kinase EF-hand_7 PF13499.6 EGR32030.1 - 1e-18 67.5 4.8 3.3e-08 33.9 1.5 3.2 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR32030.1 - 1.1e-11 43.7 3.5 8.3e-06 25.3 0.1 4.7 2 2 1 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 EGR32030.1 - 4.8e-10 38.3 5.0 1.8e-06 27.0 0.1 4.9 5 1 1 6 6 6 1 EF hand EF-hand_8 PF13833.6 EGR32030.1 - 3.6e-09 36.3 3.9 0.043 13.7 0.1 3.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_9 PF14658.6 EGR32030.1 - 0.00026 21.2 0.0 0.0055 17.0 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain Kdo PF06293.14 EGR32030.1 - 0.00031 20.1 0.3 0.001 18.4 0.0 2.0 3 0 0 3 3 3 1 Lipopolysaccharide kinase (Kdo/WaaP) family SRI PF08236.11 EGR32030.1 - 0.0023 18.0 3.4 0.0062 16.7 1.6 2.5 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain Kinase-like PF14531.6 EGR32030.1 - 0.0034 16.7 0.0 0.016 14.5 0.0 2.0 1 1 0 1 1 1 1 Kinase-like EF-hand_5 PF13202.6 EGR32030.1 - 0.013 14.9 7.7 0.018 14.5 0.1 3.6 4 0 0 4 4 4 0 EF hand APH PF01636.23 EGR32030.1 - 0.018 15.0 0.0 0.029 14.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Acetyltransf_4 PF13420.7 EGR32030.1 - 0.039 14.1 3.7 0.062 13.4 1.3 2.3 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain AAA PF00004.29 EGR32030.1 - 0.059 13.8 0.6 0.059 13.8 0.6 1.7 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) FTA2 PF13095.6 EGR32030.1 - 0.089 12.4 5.5 0.33 10.5 0.0 3.2 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Phospholamban PF04272.14 EGR32030.1 - 1.1 8.7 3.7 22 4.6 0.1 2.6 2 0 0 2 2 2 0 Phospholamban PP2C PF00481.21 EGR32031.1 - 2.4e-17 63.5 0.0 2.8e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C Virulence_fact PF13769.6 EGR32032.1 - 0.054 13.7 0.7 0.26 11.6 0.1 2.4 1 1 1 2 2 2 0 Virulence factor GDWWSH PF15667.5 EGR32032.1 - 0.076 12.4 0.1 0.14 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function with motif GDWWSH HEAT PF02985.22 EGR32034.1 - 0.0014 18.7 0.5 0.0067 16.6 0.0 2.3 3 0 0 3 3 3 1 HEAT repeat AFG1_ATPase PF03969.16 EGR32035.1 - 2.4e-74 250.4 3.6 9.3e-71 238.6 0.7 3.4 3 1 0 3 3 3 1 AFG1-like ATPase AAA PF00004.29 EGR32035.1 - 0.00063 20.2 2.0 0.002 18.5 0.0 2.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGR32035.1 - 0.0015 18.9 0.0 0.038 14.4 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGR32035.1 - 0.0016 18.7 0.0 0.011 16.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGR32035.1 - 0.026 14.9 0.1 0.23 11.9 0.0 2.8 2 0 0 2 2 2 0 RNA helicase Cyclin PF08613.11 EGR32036.1 - 4e-26 92.3 4.3 6.9e-26 91.5 4.3 1.4 1 1 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EGR32036.1 - 7.4e-06 25.7 1.6 1.2e-05 25.1 0.8 1.7 1 1 1 2 2 2 1 Cyclin, N-terminal domain E1-E2_ATPase PF00122.20 EGR32037.1 - 2.5e-39 134.6 1.0 2.5e-39 134.6 1.0 3.4 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGR32037.1 - 5.2e-39 133.8 11.4 5.2e-39 133.8 11.4 2.3 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGR32037.1 - 4.8e-23 81.1 0.2 1.2e-22 79.8 0.2 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGR32037.1 - 1.1e-14 55.2 0.6 2e-07 31.5 0.0 2.9 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGR32037.1 - 3.1e-11 42.8 0.0 8.3e-11 41.4 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGR32037.1 - 0.00024 20.9 7.1 0.0014 18.4 0.5 3.2 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase DUF812 PF05667.11 EGR32038.1 - 0.0012 17.9 23.0 0.0012 17.9 23.0 5.1 1 1 4 5 5 5 2 Protein of unknown function (DUF812) YjcZ PF13990.6 EGR32038.1 - 0.0081 15.6 7.9 0.033 13.6 7.9 2.1 1 0 0 1 1 1 1 YjcZ-like protein WD40 PF00400.32 EGR32040.1 - 2.4e-11 44.0 5.9 0.008 17.0 0.0 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR32040.1 - 4.5e-09 36.5 0.2 0.00056 20.2 0.0 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ntox35 PF15534.6 EGR32040.1 - 0.092 13.2 0.1 0.092 13.2 0.1 2.3 3 0 0 3 3 3 0 Bacterial toxin 35 UQ_con PF00179.26 EGR32041.1 - 6.8e-26 90.6 0.0 1.6e-25 89.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme CBM_20 PF00686.19 EGR32041.1 - 6.1e-20 70.9 1.6 2.3e-19 69.1 0.1 2.4 2 0 0 2 2 2 1 Starch binding domain UEV PF05743.13 EGR32041.1 - 1.9e-07 30.9 0.1 1.2e-06 28.3 0.0 2.4 2 1 0 2 2 2 1 UEV domain RWD PF05773.22 EGR32041.1 - 0.08 13.2 7.2 0.52 10.6 7.2 2.4 1 1 0 1 1 1 0 RWD domain EF-hand_1 PF00036.32 EGR32043.1 - 2.5e-29 98.6 7.4 4.4e-09 35.2 1.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGR32043.1 - 8.5e-23 80.6 6.2 1.2e-12 48.1 3.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR32043.1 - 2.1e-22 77.1 4.5 5e-08 32.3 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGR32043.1 - 1.2e-19 68.9 8.5 4.8e-08 32.2 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGR32043.1 - 1.3e-16 60.1 3.4 8.6e-06 25.5 0.0 4.0 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EGR32043.1 - 0.00022 21.1 4.2 0.011 15.6 1.0 2.2 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGR32043.1 - 0.00025 21.3 1.1 0.021 15.1 0.3 2.2 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EGR32043.1 - 0.00068 19.9 0.2 0.19 12.1 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain Sigma54_CBD PF04963.13 EGR32043.1 - 0.0064 16.4 2.6 0.019 14.8 0.2 1.9 1 1 1 2 2 2 1 Sigma-54 factor, core binding domain Dockerin_1 PF00404.18 EGR32043.1 - 0.011 15.9 4.8 0.48 10.7 0.5 3.1 1 1 1 2 2 2 0 Dockerin type I domain DUF3507 PF12015.8 EGR32043.1 - 0.013 15.2 0.5 0.023 14.4 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3507) DUF859 PF05895.12 EGR32043.1 - 0.039 12.5 0.5 0.044 12.3 0.5 1.0 1 0 0 1 1 1 0 Siphovirus protein of unknown function (DUF859) SOP4 PF17081.5 EGR32043.1 - 0.051 13.1 0.2 0.054 13.0 0.2 1.2 1 0 0 1 1 1 0 Suppressor of PMA 1-7 protein PMBR PF09373.10 EGR32043.1 - 0.071 13.3 0.1 38 4.7 0.0 3.6 4 0 0 4 4 4 0 Pseudomurein-binding repeat EF-hand_11 PF08976.11 EGR32043.1 - 0.082 13.8 0.1 0.31 11.9 0.1 1.7 1 1 1 2 2 2 0 EF-hand domain HECT PF00632.25 EGR32045.1 - 1.8e-68 231.3 1.6 4.6e-68 230.0 1.6 1.6 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Sigma54_activ_2 PF14532.6 EGR32045.1 - 0.012 15.7 0.0 0.024 14.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Peptidase_C78 PF07910.13 EGR32046.1 - 2e-46 158.2 1.0 3.8e-46 157.2 1.0 1.5 1 0 0 1 1 1 1 Peptidase family C78 Peptidase_C54 PF03416.19 EGR32046.1 - 0.00023 20.7 0.4 0.034 13.6 0.3 2.7 1 1 0 1 1 1 1 Peptidase family C54 CIDR1_gamma PF18562.1 EGR32046.1 - 0.12 12.5 0.8 0.77 9.9 0.3 2.6 2 0 0 2 2 2 0 Cysteine-Rich Interdomain Region 1 gamma DUF577 PF04510.12 EGR32046.1 - 0.15 12.0 1.1 11 5.9 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF577) PLDc_2 PF13091.6 EGR32047.1 - 8.6e-29 100.1 0.8 1.7e-28 99.1 0.8 1.5 1 0 0 1 1 1 1 PLD-like domain FAM83 PF07894.12 EGR32047.1 - 0.021 14.4 1.1 0.041 13.4 0.1 2.1 1 1 1 2 2 2 0 FAM83 A-H VPR PF00522.18 EGR32047.1 - 0.055 13.5 1.3 0.17 12.0 1.3 1.7 1 0 0 1 1 1 0 VPR/VPX protein GCP_N_terminal PF17681.1 EGR32048.1 - 1.5e-57 195.6 9.2 3.8e-57 194.3 9.2 1.7 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EGR32048.1 - 5.4e-34 118.1 25.5 6.2e-33 114.6 19.5 3.7 2 2 0 2 2 2 1 Gamma tubulin complex component C-terminal DUF4482 PF14818.6 EGR32048.1 - 1 10.3 0.0 1 10.3 0.0 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4482) Bact_lectin PF18483.1 EGR32048.1 - 2.2 8.3 7.2 32 4.5 7.2 2.6 1 1 0 1 1 1 0 Bacterial lectin FA_desaturase PF00487.24 EGR32049.1 - 6.3e-16 59.0 10.0 1.2e-07 31.9 0.7 3.1 2 1 1 3 3 3 2 Fatty acid desaturase DJ-1_PfpI PF01965.24 EGR32050.1 - 0.00043 20.1 0.0 0.001 18.9 0.0 1.6 1 1 0 1 1 1 1 DJ-1/PfpI family Acyl-CoA_dh_1 PF00441.24 EGR32051.1 - 4.1e-43 147.2 0.1 6.1e-43 146.6 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGR32051.1 - 3.4e-30 105.0 0.0 7.3e-30 103.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGR32051.1 - 1.4e-21 76.5 0.0 2.5e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGR32051.1 - 1.9e-13 50.8 0.0 2.6e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 EGR32051.1 - 0.013 16.0 0.0 0.028 15.0 0.0 1.6 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Aminotran_1_2 PF00155.21 EGR32052.1 - 3.2e-42 145.0 0.0 4.6e-42 144.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Hydrolase PF00702.26 EGR32053.1 - 1e-13 52.1 0.7 2.4e-05 24.7 0.1 3.3 2 1 0 3 3 3 3 haloacid dehalogenase-like hydrolase PhoLip_ATPase_C PF16212.5 EGR32053.1 - 1.4e-12 47.9 44.6 1.4e-12 47.9 44.6 3.5 3 1 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 EGR32053.1 - 7.1e-10 38.8 0.1 1.9e-08 34.3 0.0 2.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGR32053.1 - 6.8e-06 25.7 1.6 1.2e-05 24.9 0.0 2.3 2 0 0 2 2 2 1 E1-E2 ATPase DUF2853 PF11015.8 EGR32053.1 - 0.0056 17.3 1.4 0.017 15.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2853) Ion_trans_2 PF07885.16 EGR32054.1 - 4.6e-12 45.7 7.4 6e-12 45.4 5.2 2.5 1 1 1 2 2 2 1 Ion channel cNMP_binding PF00027.29 EGR32054.1 - 0.082 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Pkinase PF00069.25 EGR32055.1 - 6.2e-53 179.8 0.0 9e-53 179.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32055.1 - 3.8e-24 85.4 0.0 5.4e-24 84.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR32055.1 - 4.8e-05 22.8 0.0 8e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGR32055.1 - 0.0012 17.9 0.1 0.0012 17.9 0.1 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EGR32055.1 - 0.02 14.3 0.1 0.034 13.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR32055.1 - 0.032 14.1 0.0 0.053 13.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ETF_alpha PF00766.19 EGR32056.1 - 8.8e-36 121.8 0.8 1.7e-35 120.9 0.8 1.5 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.21 EGR32056.1 - 4.4e-30 104.9 0.0 6.3e-30 104.4 0.0 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain OmpH PF03938.14 EGR32056.1 - 0.011 16.1 0.6 0.027 14.8 0.6 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4355 PF14265.6 EGR32056.1 - 0.016 15.5 0.5 0.033 14.4 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) RHH_7 PF16777.5 EGR32056.1 - 0.021 15.2 0.0 0.061 13.7 0.0 1.8 1 0 0 1 1 1 0 Transcriptional regulator, RHH-like, CopG Rsbr_N PF08678.10 EGR32056.1 - 0.15 12.1 2.0 0.27 11.3 1.0 1.9 1 1 1 2 2 2 0 Rsbr N terminal MORN PF02493.20 EGR32057.1 - 1.4e-50 166.3 60.3 2.5e-07 30.2 1.1 9.4 9 0 0 9 9 9 9 MORN repeat DUF3048_C PF17479.2 EGR32057.1 - 0.12 12.7 16.2 0.43 11.0 0.2 4.4 3 2 3 6 6 6 0 Protein of unknown function (DUF3048) C-terminal domain FERM_f0 PF16511.5 EGR32057.1 - 0.8 10.1 5.3 17 5.8 0.1 3.2 3 1 1 4 4 4 0 N-terminal or F0 domain of Talin-head FERM ELFV_dehydrog_N PF02812.18 EGR32060.1 - 6.9e-37 126.2 0.0 1.2e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 EGR32060.1 - 2.6e-34 119.0 1.9 7.6e-32 111.0 1.9 2.3 1 1 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Aminotran_1_2 PF00155.21 EGR32061.1 - 1.5e-67 228.3 0.1 1.9e-67 228.0 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGR32061.1 - 4.9e-08 31.9 0.1 8.1e-08 31.2 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGR32061.1 - 4.7e-06 25.8 0.3 7.7e-06 25.1 0.3 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGR32061.1 - 0.002 17.5 0.1 0.0031 16.8 0.1 1.3 1 1 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EGR32061.1 - 0.03 13.6 0.4 0.13 11.6 0.4 1.8 1 1 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ribosomal_S8e PF01201.22 EGR32062.1 - 2.7e-51 173.3 1.1 3.6e-51 172.9 1.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e Ribosomal_S4e PF00900.20 EGR32063.1 - 1.9e-30 104.6 1.0 8.1e-30 102.6 1.0 1.9 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 EGR32063.1 - 1.2e-21 76.1 0.0 7.7e-21 73.5 0.0 2.2 2 0 0 2 2 2 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EGR32063.1 - 2.6e-18 65.8 4.6 5.4e-18 64.8 4.6 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain Sipho_tail PF05709.11 EGR32063.1 - 0.0067 15.9 0.2 0.042 13.3 0.1 2.0 1 1 0 2 2 2 1 Phage tail protein Gag_MA PF01140.19 EGR32063.1 - 0.051 13.3 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 Matrix protein (MA), p15 KOW PF00467.29 EGR32063.1 - 0.1 12.6 0.2 0.29 11.1 0.2 1.8 1 0 0 1 1 1 0 KOW motif Pkinase PF00069.25 EGR32064.1 - 3.3e-29 102.1 1.1 3.8e-29 101.9 1.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32064.1 - 2.5e-16 59.8 0.0 3e-16 59.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR32064.1 - 2.3e-10 39.8 0.2 5.7e-10 38.5 0.2 1.4 1 1 1 2 2 2 1 Fungal protein kinase APH PF01636.23 EGR32064.1 - 7.5e-06 26.0 0.0 0.0018 18.3 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGR32064.1 - 0.00014 21.3 0.1 0.0002 20.8 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGR32064.1 - 0.00014 20.9 3.9 0.00023 20.2 3.9 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 EGR32064.1 - 0.0029 17.2 0.5 0.0029 17.2 0.5 1.7 2 0 0 2 2 2 1 Choline/ethanolamine kinase PriC PF07445.12 EGR32065.1 - 0.023 14.6 0.8 0.027 14.4 0.8 1.2 1 0 0 1 1 1 0 Primosomal replication protein priC H-kinase_dim PF02895.14 EGR32066.1 - 0.097 13.1 2.0 1.3 9.5 0.3 2.6 2 1 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain SelA PF03841.13 EGR32066.1 - 0.18 10.8 0.2 0.25 10.3 0.2 1.1 1 0 0 1 1 1 0 L-seryl-tRNA selenium transferase YolD PF08863.10 EGR32066.1 - 0.23 11.5 5.5 2.9 8.0 0.1 3.2 2 1 1 3 3 3 0 YolD-like protein Ribosomal_S10 PF00338.22 EGR32067.1 - 6e-24 84.1 0.1 7.2e-24 83.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e Ferlin_C PF16165.5 EGR32067.1 - 0.0073 16.3 0.9 0.0097 15.9 0.9 1.2 1 0 0 1 1 1 1 Ferlin C-terminus Tropomyosin PF00261.20 EGR32067.1 - 0.026 13.9 1.0 0.032 13.6 1.0 1.1 1 0 0 1 1 1 0 Tropomyosin Pkinase PF00069.25 EGR32068.1 - 7.4e-62 209.1 0.1 9.5e-62 208.7 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32068.1 - 3.7e-31 108.3 0.0 5e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR32068.1 - 0.00051 19.5 0.0 0.0018 17.6 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EGR32068.1 - 0.0032 16.8 0.0 0.005 16.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGR32068.1 - 0.015 14.9 0.1 0.032 13.8 0.1 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 EGR32068.1 - 0.19 11.6 0.0 1.8 8.4 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Ntox35 PF15534.6 EGR32068.1 - 0.43 11.1 3.1 0.34 11.4 0.5 2.2 2 0 0 2 2 2 0 Bacterial toxin 35 HEAT PF02985.22 EGR32069.1 - 2.1e-11 43.1 6.4 0.078 13.3 0.0 8.1 10 0 0 10 10 9 3 HEAT repeat HEAT_2 PF13646.6 EGR32069.1 - 1.1e-07 32.1 0.0 0.03 14.7 0.0 5.7 6 0 0 6 6 6 1 HEAT repeats HEAT_EZ PF13513.6 EGR32069.1 - 9.8e-07 29.2 0.1 0.075 13.6 0.0 6.2 5 1 1 6 6 5 1 HEAT-like repeat IFRD PF05004.13 EGR32069.1 - 9e-05 21.7 5.6 0.024 13.7 0.2 3.8 4 0 0 4 4 4 2 Interferon-related developmental regulator (IFRD) TAF6_C PF07571.13 EGR32069.1 - 9.9e-05 22.6 1.7 0.94 9.9 0.0 3.7 3 0 0 3 3 2 2 TAF6 C-terminal HEAT repeat domain RTP1_C1 PF10363.9 EGR32069.1 - 0.00015 21.9 3.4 0.29 11.3 0.4 4.9 5 1 0 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 UME PF08064.13 EGR32069.1 - 0.00039 20.3 8.0 3.9 7.5 0.1 6.7 6 2 1 7 7 7 2 UME (NUC010) domain CLASP_N PF12348.8 EGR32069.1 - 0.00075 19.1 0.1 0.95 9.0 0.0 5.3 5 1 1 6 6 6 2 CLASP N terminal IBN_N PF03810.19 EGR32069.1 - 0.0052 16.7 5.7 0.0077 16.1 0.2 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain MMS19_N PF14500.6 EGR32069.1 - 0.0052 16.4 9.4 1.8 8.1 0.2 4.7 4 1 1 5 5 5 2 Dos2-interacting transcription regulator of RNA-Pol-II RIX1 PF08167.12 EGR32069.1 - 0.019 14.7 4.8 0.087 12.6 0.2 4.2 3 1 0 4 4 4 0 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 EGR32069.1 - 0.022 15.4 17.0 4.1 8.1 0.1 7.4 6 2 2 8 8 8 0 Vacuolar 14 Fab1-binding region PI3_PI4_kinase PF00454.27 EGR32069.1 - 0.06 13.1 0.2 0.22 11.3 0.1 2.0 2 0 0 2 2 2 0 Phosphatidylinositol 3- and 4-kinase Sec7_N PF12783.7 EGR32069.1 - 0.11 12.4 13.8 0.1 12.5 1.3 4.7 3 1 1 4 4 4 0 Guanine nucleotide exchange factor in Golgi transport N-terminal Nop14 PF04147.12 EGR32069.1 - 0.86 7.7 2.2 0.8 7.8 0.2 2.0 2 0 0 2 2 2 0 Nop14-like family Spc7 PF08317.11 EGR32070.1 - 0.00016 20.6 32.6 0.0027 16.6 7.9 2.1 2 0 0 2 2 2 2 Spc7 kinetochore protein DASH_Duo1 PF08651.10 EGR32070.1 - 0.0003 20.5 21.9 0.00036 20.3 2.7 5.0 4 1 1 5 5 5 1 DASH complex subunit Duo1 DUF3584 PF12128.8 EGR32070.1 - 0.0014 16.3 29.3 0.044 11.3 6.6 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3584) ADIP PF11559.8 EGR32070.1 - 0.0035 17.4 11.8 0.0035 17.4 11.8 2.6 1 1 2 3 3 3 1 Afadin- and alpha -actinin-Binding P4Ha_N PF08336.11 EGR32070.1 - 0.0077 16.3 3.1 0.0077 16.3 3.1 4.0 3 1 0 3 3 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Filament PF00038.21 EGR32070.1 - 0.012 15.2 31.3 0.066 12.8 5.9 2.5 2 1 0 2 2 2 0 Intermediate filament protein DUF4600 PF15372.6 EGR32070.1 - 0.031 14.7 5.9 0.031 14.7 5.9 3.5 2 2 2 4 4 4 0 Domain of unknown function (DUF4600) TPR_1 PF00515.28 EGR32070.1 - 0.035 13.9 2.1 0.11 12.4 2.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Vta1_C PF18097.1 EGR32070.1 - 0.043 13.5 3.1 0.069 12.9 0.5 2.5 2 0 0 2 2 2 0 Vta1 C-terminal domain TPR_10 PF13374.6 EGR32070.1 - 0.057 13.3 2.3 0.29 11.1 0.6 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGR32070.1 - 0.082 13.1 1.0 0.25 11.5 1.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat RuvA_C PF07499.13 EGR32070.1 - 0.098 13.1 0.5 9.3 6.8 0.1 3.1 2 0 0 2 2 2 0 RuvA, C-terminal domain Atg14 PF10186.9 EGR32070.1 - 0.12 11.4 28.0 0.22 10.6 7.3 2.2 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 TMF_TATA_bd PF12325.8 EGR32070.1 - 0.14 12.4 32.9 1.1 9.5 1.0 4.3 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding Chrome_Resist PF09828.9 EGR32070.1 - 0.14 12.6 2.7 2.2 8.8 0.1 3.2 2 1 1 4 4 4 0 Chromate resistance exported protein FH2 PF02181.23 EGR32070.1 - 0.18 10.9 20.1 0.012 14.8 5.2 2.3 1 1 1 2 2 2 0 Formin Homology 2 Domain DLP_helical PF18709.1 EGR32070.1 - 0.2 10.8 17.5 0.087 12.0 3.3 2.5 2 1 0 2 2 2 0 Dynamin-like helical domain MIT PF04212.18 EGR32070.1 - 0.24 11.5 11.9 0.25 11.4 0.8 3.8 4 0 0 4 4 3 0 MIT (microtubule interacting and transport) domain FliD_C PF07195.12 EGR32070.1 - 0.32 10.4 24.8 0.33 10.3 4.8 3.7 1 1 2 4 4 4 0 Flagellar hook-associated protein 2 C-terminus ATG16 PF08614.11 EGR32070.1 - 0.47 10.6 34.8 0.055 13.7 14.0 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF1664 PF07889.12 EGR32070.1 - 0.53 10.3 21.8 0.39 10.7 5.1 3.6 1 1 3 4 4 4 0 Protein of unknown function (DUF1664) DUF812 PF05667.11 EGR32070.1 - 0.64 8.8 32.8 3.4 6.4 32.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF5082 PF16888.5 EGR32070.1 - 0.89 9.8 33.1 1.7 8.9 3.2 4.3 2 2 2 4 4 4 0 Domain of unknown function (DUF5082) DUF4407 PF14362.6 EGR32070.1 - 0.93 8.8 26.1 3.3 7.0 1.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) zf-ZPR1 PF03367.13 EGR32070.1 - 0.96 9.3 18.5 1.5 8.6 1.3 3.6 1 1 3 4 4 4 0 ZPR1 zinc-finger domain DUF2458 PF10454.9 EGR32070.1 - 1.1 8.9 14.8 0.036 13.7 6.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2458) Seryl_tRNA_N PF02403.22 EGR32070.1 - 1.3 9.3 32.3 2.3 8.5 6.2 3.8 2 2 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Mt_ATP-synt_D PF05873.12 EGR32070.1 - 1.5 8.7 13.6 0.11 12.4 0.5 3.1 2 2 2 4 4 4 0 ATP synthase D chain, mitochondrial (ATP5H) Vfa1 PF08432.10 EGR32070.1 - 1.6 9.1 18.9 1.3 9.3 11.9 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 TPR_MLP1_2 PF07926.12 EGR32070.1 - 2.2 8.3 39.0 0.5 10.4 10.5 3.9 2 2 1 3 3 3 0 TPR/MLP1/MLP2-like protein Glutaredoxin2_C PF04399.13 EGR32070.1 - 2.9 7.7 17.0 0.32 10.8 0.5 4.5 1 1 1 4 4 4 0 Glutaredoxin 2, C terminal domain YvrJ PF12841.7 EGR32070.1 - 3.1 7.4 5.2 2.1 8.0 0.3 3.0 2 0 0 2 2 2 0 YvrJ protein family Exonuc_VII_L PF02601.15 EGR32070.1 - 3.5 7.1 30.0 5.1 6.6 8.0 2.2 1 1 1 2 2 2 0 Exonuclease VII, large subunit THOC7 PF05615.13 EGR32070.1 - 3.7 7.8 27.2 0.076 13.3 3.4 3.2 2 1 0 2 2 2 0 Tho complex subunit 7 DUF883 PF05957.13 EGR32070.1 - 4.3 8.0 17.6 6.6 7.4 2.4 4.4 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF883) ROS_MUCR PF05443.11 EGR32070.1 - 4.7 7.3 11.6 4.5 7.3 0.7 3.8 1 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein Goodbye PF17109.5 EGR32070.1 - 5.5 7.5 16.1 2 8.9 1.0 4.2 1 1 4 5 5 5 0 fungal STAND N-terminal Goodbye domain Fmp27_WPPW PF10359.9 EGR32070.1 - 7.8 5.2 29.9 0.89 8.3 6.3 2.4 1 1 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain DUF745 PF05335.13 EGR32070.1 - 8 6.1 26.9 0.97 9.1 2.4 3.1 1 1 1 3 3 3 0 Protein of unknown function (DUF745) FecCD PF01032.18 EGR32071.1 - 0.19 10.7 0.0 0.22 10.5 0.0 1.2 1 0 0 1 1 1 0 FecCD transport family Pkinase PF00069.25 EGR32072.1 - 3e-30 105.5 0.0 3.6e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32072.1 - 1.7e-06 27.5 0.0 2.3e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR32072.1 - 0.0056 16.6 0.0 0.0079 16.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DHHC PF01529.20 EGR32073.1 - 2.2e-32 112.0 14.0 2.2e-32 112.0 14.0 2.8 2 1 1 3 3 3 1 DHHC palmitoyltransferase YccF PF03733.13 EGR32073.1 - 0.0032 18.1 2.5 0.51 11.1 0.3 2.8 2 0 0 2 2 2 2 Inner membrane component domain DUF4201 PF13870.6 EGR32075.1 - 3.5e-21 75.7 13.9 3.5e-21 75.7 13.9 2.8 2 1 1 3 3 3 1 Domain of unknown function (DUF4201) GxGYxYP_C PF14323.6 EGR32075.1 - 0.069 13.0 0.8 0.085 12.7 0.8 1.3 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain DUF501 PF04417.12 EGR32075.1 - 2 8.2 5.9 0.47 10.3 0.6 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF501) Ion_trans PF00520.31 EGR32076.1 - 3.2e-12 46.2 30.8 5.6e-12 45.4 29.8 1.9 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 EGR32076.1 - 2.6e-10 40.1 8.2 9.9e-10 38.3 8.2 2.0 1 1 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 EGR32076.1 - 1.2e-08 34.9 0.0 2.4e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain zf-CCHC_4 PF14392.6 EGR32076.1 - 0.00025 20.7 0.7 0.00069 19.3 0.7 1.7 1 0 0 1 1 1 1 Zinc knuckle Mu-like_Com PF10122.9 EGR32076.1 - 0.026 13.9 0.2 0.052 13.0 0.2 1.4 1 0 0 1 1 1 0 Mu-like prophage protein Com BAG PF02179.16 EGR32076.1 - 0.11 13.0 2.3 0.74 10.3 2.3 2.6 1 0 0 1 1 1 0 BAG domain RRM_1 PF00076.22 EGR32077.1 - 8.1e-18 64.0 0.1 1.5e-17 63.1 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LMF1 PF06762.14 EGR32079.1 - 5.6e-38 131.2 11.2 6.7e-38 130.9 11.2 1.0 1 0 0 1 1 1 1 Lipase maturation factor Pkinase PF00069.25 EGR32080.1 - 1.1e-08 34.8 1.7 1.7e-08 34.2 1.7 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32080.1 - 8.2e-05 22.0 1.0 0.00022 20.6 1.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGR32081.1 - 2e-55 188.0 6.7 4e-54 183.7 6.7 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32081.1 - 7.1e-26 91.0 0.2 2.4e-25 89.3 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR32081.1 - 0.00096 19.1 0.0 0.074 13.0 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EGR32081.1 - 0.0039 16.7 2.2 0.0097 15.4 2.2 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Pkinase_fungal PF17667.1 EGR32081.1 - 0.0067 15.3 0.0 0.01 14.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR32081.1 - 0.015 14.7 0.2 0.038 13.3 0.2 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Radical_SAM_C PF16199.5 EGR32081.1 - 0.022 14.7 0.1 0.06 13.4 0.1 1.7 1 0 0 1 1 1 0 Radical_SAM C-terminal domain DUF676 PF05057.14 EGR32082.1 - 1.1e-47 162.4 0.2 2.7e-47 161.1 0.2 1.6 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGR32082.1 - 4.2e-11 43.1 0.1 6.9e-11 42.4 0.1 1.4 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 EGR32082.1 - 1.6e-06 28.1 0.0 2.8e-06 27.2 0.0 1.5 1 0 0 1 1 1 1 PGAP1-like protein DUF3657 PF12394.8 EGR32083.1 - 9.2e-24 83.8 17.1 1e-22 80.4 17.1 2.7 1 1 0 1 1 1 1 Protein FAM135 Kelch_1 PF01344.25 EGR32084.1 - 1.9e-17 62.6 0.0 1.3e-10 40.7 0.0 2.1 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 EGR32084.1 - 1.8e-15 56.6 0.0 2.4e-07 30.7 0.0 2.0 2 0 0 2 2 2 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EGR32084.1 - 6.4e-14 51.7 0.0 2.3e-07 30.9 0.0 2.0 1 1 1 2 2 2 2 Kelch motif Kelch_5 PF13854.6 EGR32084.1 - 1.2e-09 37.9 0.3 0.00035 20.5 0.1 2.1 2 0 0 2 2 2 2 Kelch motif Kelch_2 PF07646.15 EGR32084.1 - 3.4e-07 30.0 0.0 0.0013 18.6 0.0 2.1 2 0 0 2 2 2 2 Kelch motif Kelch_3 PF13415.6 EGR32084.1 - 1.4e-05 25.2 0.0 0.002 18.4 0.0 2.5 3 0 0 3 3 3 1 Galactose oxidase, central domain DENN PF02141.21 EGR32085.1 - 6.9e-21 75.0 2.0 1e-20 74.5 2.0 1.2 1 0 0 1 1 1 1 DENN (AEX-3) domain SPA PF08616.10 EGR32085.1 - 2.4e-06 27.5 0.9 3.1e-06 27.1 0.9 1.1 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 EGR32085.1 - 0.0013 17.5 1.5 0.054 12.2 0.5 2.2 1 1 1 2 2 2 2 Transport protein Avl9 DUF2347 PF09804.9 EGR32085.1 - 0.19 11.3 0.6 0.23 11.0 0.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2347) Pkinase PF00069.25 EGR32086.1 - 2.8e-68 230.2 0.0 3.2e-68 230.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32086.1 - 7.6e-37 127.0 0.0 9.6e-37 126.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR32086.1 - 2.9e-05 23.6 0.0 4.7e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PT-HINT PF07591.11 EGR32086.1 - 0.031 14.5 0.0 0.063 13.5 0.0 1.5 1 0 0 1 1 1 0 Pretoxin HINT domain TTL PF03133.15 EGR32087.1 - 4.5e-16 58.8 0.3 5.6e-16 58.5 0.3 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR32087.1 - 2.6e-05 23.6 0.0 2.7e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.13 EGR32087.1 - 0.0028 17.2 0.0 0.0034 16.9 0.0 1.2 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_ST PF14397.6 EGR32087.1 - 0.061 12.6 0.0 0.077 12.2 0.0 1.1 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp SLC12 PF03522.15 EGR32088.1 - 0.012 14.7 19.7 0.016 14.2 19.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 LAP1C PF05609.12 EGR32088.1 - 0.014 14.6 21.6 0.017 14.2 21.6 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) SOBP PF15279.6 EGR32088.1 - 0.06 14.0 12.4 0.084 13.5 12.4 1.4 1 0 0 1 1 1 0 Sine oculis-binding protein Ndc1_Nup PF09531.10 EGR32088.1 - 0.11 11.2 11.6 0.13 10.9 11.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Macoilin PF09726.9 EGR32088.1 - 0.23 10.0 19.9 0.28 9.7 19.9 1.1 1 0 0 1 1 1 0 Macoilin family CDC45 PF02724.14 EGR32088.1 - 0.33 9.2 20.8 0.38 9.0 20.8 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4407 PF14362.6 EGR32088.1 - 0.4 10.0 17.1 0.47 9.8 17.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) V_ATPase_I PF01496.19 EGR32088.1 - 0.57 8.0 23.0 0.7 7.7 23.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CAML PF14963.6 EGR32088.1 - 0.79 9.8 8.8 1 9.4 8.8 1.2 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand Raftlin PF15250.6 EGR32088.1 - 1.7 7.3 20.2 2.3 6.9 20.2 1.1 1 0 0 1 1 1 0 Raftlin CAC1F_C PF16885.5 EGR32088.1 - 2.3 7.8 16.7 2.8 7.5 16.7 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Dapper PF15268.6 EGR32088.1 - 4.7 5.9 26.7 5.7 5.7 26.7 1.0 1 0 0 1 1 1 0 Dapper ABC2_membrane_3 PF12698.7 EGR32088.1 - 6.2 5.8 13.0 8.4 5.4 13.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein RR_TM4-6 PF06459.12 EGR32088.1 - 8 6.2 31.3 15 5.3 31.3 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 EGR32088.1 - 8.4 6.4 16.3 14 5.6 16.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EF-hand_1 PF00036.32 EGR32091.1 - 3.9e-15 54.2 3.5 1.2e-08 33.8 0.5 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGR32091.1 - 3.3e-14 53.1 2.4 1.8e-13 50.7 2.4 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGR32091.1 - 9.7e-14 51.0 2.1 1.4e-10 40.8 0.5 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR32091.1 - 3.8e-12 45.1 2.7 1.6e-06 27.6 0.5 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_9 PF14658.6 EGR32091.1 - 2.8e-08 34.0 0.0 3.7e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain EF-hand_4 PF12763.7 EGR32091.1 - 5.9e-06 26.2 1.2 7.6e-06 25.8 1.2 1.2 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 EGR32091.1 - 6.2e-06 25.5 2.4 7.8e-05 22.0 0.1 2.5 2 1 0 2 2 2 1 EF hand EF-hand_10 PF14788.6 EGR32091.1 - 0.0059 16.4 1.1 0.012 15.5 1.1 1.5 1 0 0 1 1 1 1 EF hand Caleosin PF05042.13 EGR32091.1 - 0.012 15.6 0.9 2 8.3 0.1 2.0 1 1 1 2 2 2 0 Caleosin related protein SPARC_Ca_bdg PF10591.9 EGR32091.1 - 0.035 14.4 0.1 0.043 14.1 0.1 1.1 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region SUB1_ProdP9 PF18213.1 EGR32091.1 - 0.054 13.3 0.2 0.072 12.9 0.2 1.2 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 EF-hand_13 PF17958.1 EGR32091.1 - 0.074 12.9 0.0 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 EF-hand domain Utp13 PF08625.11 EGR32092.1 - 6.4e-27 94.2 8.3 1e-26 93.5 8.3 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain WD40 PF00400.32 EGR32092.1 - 1e-25 89.4 10.8 2.2e-08 34.6 0.4 4.3 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR32092.1 - 1.7e-10 41.0 3.3 1.1e-07 32.1 0.3 3.7 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGR32092.1 - 0.0014 17.4 0.2 0.5 8.9 0.0 3.2 3 1 0 3 3 3 1 Nucleoporin Nup120/160 MscL PF01741.18 EGR32092.1 - 0.7 10.2 6.1 0.11 12.8 1.6 1.9 2 0 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL Clathrin_H_link PF13838.6 EGR32092.1 - 2.7 8.0 5.8 0.6 10.1 0.3 2.5 3 0 0 3 3 3 0 Clathrin-H-link TPR_12 PF13424.6 EGR32094.1 - 6e-25 87.3 1.0 2.8e-17 62.8 0.1 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGR32094.1 - 2.2e-22 78.2 0.0 3.8e-10 39.3 0.0 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGR32094.1 - 5.5e-13 48.1 4.4 6e-05 22.7 0.1 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGR32094.1 - 1.9e-12 46.3 2.8 0.0047 16.9 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGR32094.1 - 2.6e-12 45.9 3.6 0.0083 16.1 0.0 4.2 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGR32094.1 - 3.3e-09 36.3 12.1 0.016 15.4 0.1 4.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGR32094.1 - 7.8e-09 35.9 2.4 0.00063 20.2 0.5 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGR32094.1 - 6.7e-05 23.3 1.4 1.1 10.0 0.1 4.8 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGR32094.1 - 0.00055 20.5 0.1 1.2 10.2 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR32094.1 - 0.0011 19.1 3.5 0.0089 16.2 0.3 3.0 2 2 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EGR32094.1 - 0.0013 19.0 2.2 3.1 8.4 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat AAA_31 PF13614.6 EGR32094.1 - 0.011 15.7 4.1 0.14 12.0 0.4 2.0 1 1 1 2 2 2 0 AAA domain TPR_MalT PF17874.1 EGR32094.1 - 0.012 15.1 0.4 0.28 10.5 0.0 1.9 1 1 1 2 2 2 0 MalT-like TPR region Imm61 PF15598.6 EGR32094.1 - 0.089 12.7 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 Immunity protein 61 DUF489 PF04356.12 EGR32094.1 - 0.12 12.4 2.1 0.12 12.3 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF489) DIOX_N PF14226.6 EGR32095.1 - 0.00015 22.5 0.0 0.00025 21.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGR32095.1 - 0.04 14.4 0.0 0.071 13.6 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.6 EGR32096.1 - 0.00016 22.4 0.0 0.00027 21.7 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGR32096.1 - 0.036 14.6 0.0 0.068 13.7 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily TINF2_N PF14973.6 EGR32097.1 - 0.079 13.3 1.8 0.093 13.1 1.8 1.2 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus PARG_cat PF05028.14 EGR32097.1 - 0.087 12.1 1.7 0.095 12.0 1.7 1.1 1 0 0 1 1 1 0 Poly (ADP-ribose) glycohydrolase (PARG) PseudoU_synth_1 PF01416.20 EGR32098.1 - 3.2e-12 46.9 0.3 1e-10 42.0 0.1 2.6 2 1 0 2 2 2 1 tRNA pseudouridine synthase DUF2344 PF10105.9 EGR32098.1 - 0.00014 21.8 1.2 0.00029 20.7 1.2 1.6 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2344) Atypical_Card PF18461.1 EGR32098.1 - 5.6 7.3 8.4 13 6.1 0.1 3.7 4 0 0 4 4 4 0 Atypical caspase recruitment domain Tctex-1 PF03645.13 EGR32099.1 - 1.3e-18 67.1 0.0 1.5e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family MADF_DNA_bdg PF10545.9 EGR32099.1 - 0.15 12.4 0.5 4.8 7.6 0.1 2.1 2 0 0 2 2 2 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Helicase_C PF00271.31 EGR32100.1 - 1.9e-18 66.8 0.1 1.9e-18 66.8 0.1 3.1 2 1 0 2 2 2 1 Helicase conserved C-terminal domain Spt20 PF12090.8 EGR32100.1 - 0.00024 20.8 33.1 0.00041 20.0 33.1 1.3 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 EGR32100.1 - 0.41 10.6 26.8 0.42 10.6 26.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CLN3 PF02487.17 EGR32100.1 - 1.4 7.9 8.7 1.8 7.5 8.7 1.1 1 0 0 1 1 1 0 CLN3 protein ALMT PF11744.8 EGR32100.1 - 3.8 6.2 10.7 3.7 6.3 10.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DEAD PF00270.29 EGR32101.1 - 8.1e-52 175.5 0.0 1e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGR32101.1 - 2.3e-08 34.3 0.0 3.1e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EGR32101.1 - 0.037 13.7 0.0 0.073 12.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.25 EGR32104.1 - 2.4e-58 197.6 0.0 5.6e-58 196.4 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 EGR32104.1 - 5.5e-33 112.9 0.2 3.8e-16 58.9 0.0 3.7 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 EGR32104.1 - 8.7e-28 97.3 0.0 2.2e-27 96.0 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR32104.1 - 2.7e-06 26.5 1.6 1.4e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGR32104.1 - 0.00066 19.1 1.0 0.0028 17.0 0.0 2.6 3 0 0 3 3 3 1 Kinase-like RIB43A PF05914.12 EGR32104.1 - 0.016 13.9 9.7 0.033 12.9 9.7 1.4 1 0 0 1 1 1 0 RIB43A APH PF01636.23 EGR32104.1 - 0.16 11.8 0.2 0.44 10.4 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 EGR32105.1 - 1.9e-62 211.1 0.0 1.9e-62 211.1 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32105.1 - 3.7e-31 108.4 0.0 8.5e-31 107.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 EGR32105.1 - 1.9e-30 104.8 0.1 2.9e-15 56.1 0.0 3.5 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_fungal PF17667.1 EGR32105.1 - 3.3e-05 22.8 0.0 3.3e-05 22.8 0.0 1.9 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 EGR32105.1 - 0.0004 19.8 0.0 0.0004 19.8 0.0 2.7 3 1 0 3 3 3 1 Kinase-like APH PF01636.23 EGR32105.1 - 0.0011 19.0 0.0 0.0037 17.2 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family COX5B PF01215.19 EGR32106.1 - 2.5e-11 43.4 0.0 6.6e-11 42.0 0.0 1.7 2 0 0 2 2 2 1 Cytochrome c oxidase subunit Vb Imm40 PF15569.6 EGR32106.1 - 0.19 11.9 2.2 2.1 8.5 0.2 2.6 2 0 0 2 2 2 0 Immunity protein 40 tRNA-synt_1c PF00749.21 EGR32107.1 - 7.5e-15 54.6 0.3 1.9e-06 27.0 0.2 2.3 1 1 1 2 2 2 2 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGR32107.1 - 2e-10 40.8 0.0 4.6e-09 36.4 0.0 2.2 1 1 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain MORN PF02493.20 EGR32108.1 - 3.8e-20 70.5 15.3 0.00013 21.6 0.3 5.5 5 1 0 5 5 5 5 MORN repeat AGTRAP PF06396.11 EGR32109.1 - 7e-05 22.7 0.2 0.00013 21.8 0.0 1.5 1 1 1 2 2 2 1 Angiotensin II, type I receptor-associated protein (AGTRAP) Mem_trans PF03547.18 EGR32109.1 - 0.00021 19.8 1.0 0.00024 19.6 1.0 1.1 1 0 0 1 1 1 1 Membrane transport protein DUF2746 PF10874.8 EGR32109.1 - 0.00063 20.1 0.4 0.00082 19.8 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2746) SID-1_RNA_chan PF13965.6 EGR32109.1 - 0.00081 17.9 0.7 0.00098 17.7 0.7 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 UPF0242 PF06785.11 EGR32109.1 - 0.00087 19.4 2.4 0.001 19.2 2.4 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus RNA_pol_Rpc4 PF05132.14 EGR32109.1 - 0.0014 19.0 0.3 0.0014 19.0 0.3 1.1 1 0 0 1 1 1 1 RNA polymerase III RPC4 Zip PF02535.22 EGR32109.1 - 0.0021 17.3 0.5 0.0025 17.1 0.5 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4834 PF16118.5 EGR32109.1 - 0.0027 18.6 8.8 0.0072 17.3 8.8 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4834) CLN3 PF02487.17 EGR32109.1 - 0.0037 16.4 0.3 0.0044 16.1 0.3 1.0 1 0 0 1 1 1 1 CLN3 protein BatA PF07584.11 EGR32109.1 - 0.0052 17.1 0.0 0.012 16.0 0.0 1.6 2 0 0 2 2 1 1 Aerotolerance regulator N-terminal V_ATPase_I PF01496.19 EGR32109.1 - 0.0074 14.3 3.2 0.0085 14.1 3.2 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family MLANA PF14991.6 EGR32109.1 - 0.017 15.4 0.3 0.017 15.4 0.3 2.0 1 1 1 2 2 2 0 Protein melan-A Syndecan PF01034.20 EGR32109.1 - 0.031 14.2 0.2 0.031 14.2 0.2 1.7 2 0 0 2 2 2 0 Syndecan domain MAP17 PF15807.5 EGR32109.1 - 0.072 13.3 7.5 0.087 13.1 6.9 1.4 1 1 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Tmemb_9 PF05434.11 EGR32109.1 - 0.15 11.9 9.7 0.28 11.1 9.7 1.4 1 1 0 1 1 1 0 TMEM9 FixQ PF05545.11 EGR32109.1 - 0.17 11.9 1.0 0.36 10.8 1.0 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ Gon7 PF08738.10 EGR32109.1 - 0.17 12.0 10.4 0.23 11.5 10.4 1.2 1 0 0 1 1 1 0 Gon7 family ASFV_J13L PF05568.11 EGR32109.1 - 0.18 11.5 0.1 0.25 11.1 0.1 1.2 1 0 0 1 1 1 0 African swine fever virus J13L protein 7TM_GPCR_Srv PF10323.9 EGR32109.1 - 0.62 9.4 5.8 3.7 6.8 5.8 1.9 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srv FAM176 PF14851.6 EGR32109.1 - 0.92 9.2 10.4 12 5.5 10.4 2.1 1 1 0 1 1 1 0 FAM176 family PTPRCAP PF15713.5 EGR32109.1 - 1 9.6 10.0 1.1 9.5 10.0 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Neur_chan_memb PF02932.16 EGR32109.1 - 2.2 8.3 8.3 3.9 7.5 8.3 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SIT PF15330.6 EGR32109.1 - 7.1 7.1 9.5 34 4.9 9.5 2.0 1 1 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT DUF2407_C PF13373.6 EGR32109.1 - 7.3 6.8 14.0 2.5 8.3 8.2 2.0 2 0 0 2 2 2 0 DUF2407 C-terminal domain MFS_1 PF07690.16 EGR32110.1 - 0.008 15.1 8.8 0.0087 15.0 8.8 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily ATP1G1_PLM_MAT8 PF02038.16 EGR32110.1 - 0.16 11.4 0.7 0.32 10.5 0.7 1.5 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family HRG PF16954.5 EGR32110.1 - 0.66 10.4 5.1 8.3 6.9 0.9 2.4 2 0 0 2 2 2 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Peptidase_S49 PF01343.18 EGR32111.1 - 1.1e-05 25.4 0.1 1.2e-05 25.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase family S49 Mpv17_PMP22 PF04117.12 EGR32112.1 - 0.0036 17.5 7.7 0.077 13.2 7.7 2.5 1 1 0 1 1 1 1 Mpv17 / PMP22 family GST_N PF02798.20 EGR32113.1 - 1.8e-06 28.2 0.4 1.8e-06 28.2 0.4 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain LSM PF01423.22 EGR32114.1 - 3.2e-17 62.0 1.8 4e-17 61.7 1.8 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EGR32114.1 - 0.00048 19.7 0.1 0.00063 19.3 0.1 1.2 1 0 0 1 1 1 1 Hfq protein Gemin7 PF11095.8 EGR32114.1 - 0.13 12.1 0.0 0.23 11.4 0.0 1.5 1 1 0 1 1 1 0 Gem-associated protein 7 (Gemin7) TerB PF05099.13 EGR32116.1 - 0.96 9.4 7.0 0.093 12.7 0.6 2.5 3 0 0 3 3 3 0 Tellurite resistance protein TerB GBP PF02263.19 EGR32117.1 - 6.2e-58 196.1 1.9 7.5e-58 195.8 1.9 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 EGR32117.1 - 1.5e-06 27.8 1.1 2e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Guanylate-binding protein, C-terminal domain MMR_HSR1 PF01926.23 EGR32117.1 - 0.0017 18.4 0.2 0.0065 16.5 0.2 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase VSP PF03302.13 EGR32118.1 - 0.0087 15.0 4.4 0.0087 15.0 4.4 2.3 1 1 1 2 2 2 2 Giardia variant-specific surface protein cEGF PF12662.7 EGR32118.1 - 0.073 13.0 0.5 0.073 13.0 0.5 4.5 5 0 0 5 5 5 0 Complement Clr-like EGF-like DUF4637 PF15470.6 EGR32118.1 - 2.1 8.1 13.9 5.6 6.7 1.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) PTEN_C2 PF10409.9 EGR32119.1 - 6e-19 68.1 4.1 6e-19 68.1 4.1 2.8 2 1 0 2 2 2 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 EGR32119.1 - 4.5e-07 29.7 0.3 4.5e-07 29.7 0.3 2.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGR32119.1 - 4.2e-06 26.5 0.1 4.2e-06 26.5 0.1 2.5 3 0 0 3 3 3 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 EGR32119.1 - 0.001 18.8 1.0 0.0017 18.0 0.1 1.8 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 EGR32119.1 - 0.018 15.0 0.5 0.018 15.0 0.5 1.9 2 1 0 2 2 2 0 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EGR32119.1 - 0.029 14.5 4.0 0.12 12.4 3.2 2.4 1 1 1 2 2 2 0 Inositol hexakisphosphate Pkinase PF00069.25 EGR32120.1 - 4.2e-36 124.7 0.0 4.8e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32120.1 - 2.1e-24 86.2 0.0 2.5e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR32120.1 - 0.0045 16.3 0.0 0.0059 16.0 0.0 1.4 1 1 0 1 1 1 1 Kinase-like DUF4116 PF13475.6 EGR32120.1 - 0.03 14.0 3.9 0.097 12.4 1.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DNA_pol_E_B PF04042.16 EGR32120.1 - 0.13 11.5 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B DKCLD PF08068.12 EGR32121.1 - 1.4e-31 108.3 1.7 1.8e-30 104.8 0.5 2.7 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 EGR32121.1 - 1.9e-20 72.7 0.1 3.9e-20 71.8 0.1 1.5 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 EGR32121.1 - 2.4e-20 73.4 4.7 1.2e-18 67.9 0.8 3.6 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 EGR32121.1 - 5.1e-19 68.0 0.5 1.3e-18 66.7 0.5 1.8 1 0 0 1 1 1 1 PUA domain Ant_C PF05586.11 EGR32121.1 - 0.068 13.8 0.5 0.27 11.9 0.6 1.9 2 0 0 2 2 2 0 Anthrax receptor C-terminus region UPF0113 PF03657.13 EGR32121.1 - 0.11 12.7 0.0 0.37 11.1 0.0 1.9 1 0 0 1 1 1 0 UPF0113 PUA domain DEAD PF00270.29 EGR32122.1 - 4.2e-43 147.2 0.1 6.5e-42 143.3 0.1 2.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR32122.1 - 1.5e-31 109.0 0.2 1.5e-31 109.0 0.2 4.1 4 1 0 4 4 4 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGR32122.1 - 0.11 12.7 4.1 6 7.1 0.0 3.9 4 0 0 4 4 4 0 AAA domain Mito_carr PF00153.27 EGR32123.1 - 6.2e-67 221.6 1.9 3.8e-22 78.0 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGR32123.1 - 0.059 12.5 0.3 9.1 5.3 0.0 3.1 3 0 0 3 3 3 0 Gammaproteobacterial serine protease Ribosomal_L39 PF00832.20 EGR32123.1 - 0.064 12.9 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 Ribosomal L39 protein WD40 PF00400.32 EGR32124.1 - 4.1e-21 74.9 3.0 1.6e-05 25.6 0.7 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR32124.1 - 9.7e-13 48.2 0.5 0.00015 22.0 0.0 5.3 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGR32124.1 - 5e-06 26.1 2.8 4.2e-05 23.0 2.8 2.4 1 1 0 1 1 1 1 WD40-like domain BBS2_Mid PF14783.6 EGR32124.1 - 2.6e-05 24.2 0.1 0.24 11.5 0.0 3.8 2 2 2 4 4 4 2 Ciliary BBSome complex subunit 2, middle region ELYS-bb PF16687.5 EGR32124.1 - 0.076 11.6 0.1 1.1 7.8 0.0 2.3 1 1 2 3 3 3 0 beta-propeller of ELYS nucleoporin DUF2828 PF11443.8 EGR32124.1 - 0.14 10.2 0.0 0.19 9.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Ribonuc_L-PSP PF01042.21 EGR32125.1 - 3e-38 130.5 0.0 3.5e-38 130.3 0.0 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP GIT1_C PF12205.8 EGR32125.1 - 0.073 13.2 0.2 0.14 12.3 0.0 1.5 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term VIT1 PF01988.19 EGR32126.1 - 7.4e-42 143.7 14.6 2.6e-29 102.7 0.1 2.1 1 1 1 2 2 2 2 VIT family DUF3040 PF11239.8 EGR32126.1 - 3.4 8.0 6.3 20 5.5 0.1 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) Aldedh PF00171.22 EGR32128.1 - 1.7e-111 373.0 0.0 4.5e-58 196.9 0.0 2.0 1 1 1 2 2 2 2 Aldehyde dehydrogenase family LuxC PF05893.14 EGR32128.1 - 0.018 14.1 0.1 0.089 11.8 0.0 2.0 2 0 0 2 2 2 0 Acyl-CoA reductase (LuxC) TetR_C_5 PF08360.11 EGR32128.1 - 0.067 13.4 2.5 1.7 8.8 0.5 2.4 2 0 0 2 2 2 0 QacR-like protein, C-terminal region DUF498 PF04430.14 EGR32129.1 - 2.8e-20 72.4 0.0 3.4e-20 72.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) RNA_pol_Rpb6 PF01192.22 EGR32130.1 - 5.8e-15 54.9 0.5 5.1e-14 51.9 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb6 Helicase_C PF00271.31 EGR32130.1 - 2.3e-13 50.4 0.2 2.3e-13 50.4 0.2 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain TPR_1 PF00515.28 EGR32132.1 - 1.6e-11 43.5 5.6 9.7e-06 25.2 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGR32132.1 - 1.1e-09 37.6 3.8 0.00018 21.4 0.3 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGR32132.1 - 1e-07 31.4 0.1 0.00043 20.1 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGR32132.1 - 6.8e-05 22.5 0.1 0.00018 21.1 0.1 1.8 1 1 0 1 1 1 1 TPR repeat TPR_8 PF13181.6 EGR32132.1 - 8.2e-05 22.5 1.5 0.31 11.4 0.0 3.2 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGR32132.1 - 0.0005 20.3 0.1 0.055 13.8 0.3 2.4 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGR32132.1 - 0.00093 19.7 0.0 0.0024 18.3 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGR32132.1 - 0.05 13.8 0.0 0.099 12.8 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGR32132.1 - 0.11 13.2 0.0 0.31 11.7 0.0 1.8 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGR32132.1 - 0.12 13.1 3.1 22 6.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Tsi6 PF18660.1 EGR32132.1 - 0.14 12.2 5.5 0.56 10.3 0.3 3.1 2 0 0 2 2 2 0 Tsi6 Peptidase_M14 PF00246.24 EGR32133.1 - 4e-16 59.7 0.3 2.6e-15 57.0 0.0 2.5 2 1 0 2 2 2 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 EGR32133.1 - 4.1e-06 27.1 3.7 4.1e-06 27.1 3.7 3.3 3 1 0 3 3 3 1 Cytosolic carboxypeptidase N-terminal domain ThiF PF00899.21 EGR32134.1 - 7.2e-16 58.3 0.0 1.9e-15 56.9 0.0 1.6 1 1 0 1 1 1 1 ThiF family KIF1B PF12423.8 EGR32134.1 - 0.1 13.1 0.7 0.1 13.1 0.7 2.3 2 0 0 2 2 2 0 Kinesin protein 1B CHD5 PF04420.14 EGR32134.1 - 0.11 12.3 2.1 4 7.3 0.8 2.5 2 0 0 2 2 2 0 CHD5-like protein DUF1492 PF07374.11 EGR32134.1 - 1 9.5 5.9 2.7 8.2 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1492) ANAPC4_WD40 PF12894.7 EGR32135.1 - 1.2e-06 28.8 0.0 0.21 11.9 0.0 3.8 3 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGR32135.1 - 3.6e-06 27.6 1.7 0.027 15.4 0.1 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat PQQ PF01011.21 EGR32135.1 - 0.0014 18.5 0.1 0.086 12.8 0.1 2.8 2 0 0 2 2 2 1 PQQ enzyme repeat eIF2A PF08662.11 EGR32135.1 - 0.0021 18.0 0.0 0.21 11.5 0.0 3.2 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A RAB3GAP2_N PF14655.6 EGR32135.1 - 0.049 12.9 0.0 0.13 11.5 0.0 1.6 1 1 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PQQ_2 PF13360.6 EGR32135.1 - 0.085 12.4 0.0 5.2 6.6 0.0 2.2 2 0 0 2 2 2 0 PQQ-like domain Pam16 PF03656.13 EGR32137.1 - 0.092 12.8 1.2 0.14 12.2 1.2 1.4 1 0 0 1 1 1 0 Pam16 Amino_oxidase PF01593.24 EGR32138.1 - 9.7e-32 110.8 0.0 4e-16 59.3 0.0 2.0 1 1 1 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGR32138.1 - 3.5e-13 49.6 0.0 6e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 EGR32138.1 - 7.6e-06 25.0 0.0 1.1e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 MCRA family NAD_binding_9 PF13454.6 EGR32138.1 - 0.00039 20.4 0.0 0.00067 19.7 0.0 1.3 1 0 0 1 1 1 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 EGR32138.1 - 0.0018 17.6 0.1 0.0025 17.1 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGR32138.1 - 0.0035 16.6 0.0 0.0046 16.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGR32138.1 - 0.0057 15.8 0.1 0.008 15.3 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGR32138.1 - 0.0062 16.2 0.2 0.016 14.8 0.1 1.6 1 1 1 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGR32138.1 - 0.0073 15.1 0.1 0.012 14.3 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein Thi4 PF01946.17 EGR32138.1 - 0.053 12.8 0.0 0.089 12.0 0.0 1.2 1 0 0 1 1 1 0 Thi4 family AlaDh_PNT_C PF01262.21 EGR32138.1 - 0.19 11.0 0.0 0.3 10.4 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EGR32138.1 - 0.22 10.8 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase GAF_2 PF13185.6 EGR32139.1 - 4.6e-07 30.2 0.0 5.3e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 GAF domain PQ-loop PF04193.14 EGR32141.1 - 8.5e-14 51.1 2.3 8.5e-14 51.1 2.3 1.8 2 0 0 2 2 2 1 PQ loop repeat Metallophos_2 PF12850.7 EGR32142.1 - 1.6e-21 77.2 0.0 1.8e-21 77.0 0.0 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EGR32142.1 - 0.00068 20.2 0.7 0.0085 16.6 0.7 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase eIF3g PF12353.8 EGR32143.1 - 0.0039 17.6 6.7 0.0061 17.0 5.5 2.0 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G DUF2129 PF09902.9 EGR32143.1 - 0.061 13.4 0.1 4.9 7.3 0.0 3.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) DUF572 PF04502.13 EGR32144.1 - 6.7 6.2 27.5 1.2 8.6 22.7 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) RRM_1 PF00076.22 EGR32145.1 - 2.8e-40 136.0 9.1 1.2e-12 47.4 0.3 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGR32145.1 - 1e-09 38.3 4.3 0.0015 18.6 0.0 4.2 2 2 0 3 3 3 3 RNA recognition motif Nup35_RRM_2 PF14605.6 EGR32145.1 - 7.2e-06 25.9 0.3 0.65 10.0 0.0 3.7 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif DUF3912 PF13051.6 EGR32145.1 - 0.074 13.3 0.3 0.074 13.3 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3912) IF2_N PF04760.15 EGR32145.1 - 0.093 12.6 4.9 11 5.9 0.0 4.2 4 0 0 4 4 4 0 Translation initiation factor IF-2, N-terminal region PHM7_cyt PF14703.6 EGR32145.1 - 0.12 12.5 18.6 1.4 9.1 6.1 4.7 2 1 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter RL PF17797.1 EGR32145.1 - 0.15 12.0 8.8 0.62 10.0 0.2 4.0 4 0 0 4 4 4 0 RL domain DUF2492 PF10678.9 EGR32145.1 - 0.15 12.3 1.4 6.6 7.1 0.2 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF2492) Vps4_C PF09336.10 EGR32145.1 - 0.17 11.9 0.5 12 5.9 0.0 3.0 3 0 0 3 3 3 0 Vps4 C terminal oligomerisation domain RNA_bind PF08675.11 EGR32145.1 - 0.36 10.9 3.6 13 5.9 0.0 4.3 4 2 1 5 5 5 0 RNA binding domain Metallophos PF00149.28 EGR32146.1 - 1.4e-22 81.3 1.8 1.4e-22 81.3 1.8 1.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 EGR32146.1 - 0.011 16.0 1.0 0.39 11.0 0.1 2.4 2 0 0 2 2 2 0 PPP5 TPR repeat region Metallophos_2 PF12850.7 EGR32146.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain KH_1 PF00013.29 EGR32148.1 - 6.3e-05 22.7 0.7 9.2e-05 22.2 0.7 1.2 1 0 0 1 1 1 1 KH domain MFS_2 PF13347.6 EGR32149.1 - 4.2e-20 71.7 8.0 4.2e-20 71.7 8.0 2.3 2 0 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 EGR32149.1 - 3.4e-10 39.4 25.2 5.6e-07 28.8 3.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 EGR32149.1 - 0.053 12.5 0.1 0.099 11.6 0.0 1.5 2 0 0 2 2 2 0 PUCC protein MFS_2 PF13347.6 EGR32150.1 - 5.6e-29 101.0 22.5 2.2e-24 85.8 0.4 3.0 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 EGR32150.1 - 2.9e-15 56.1 8.3 9.3e-10 38.0 0.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PUCC PF03209.15 EGR32150.1 - 0.074 12.0 3.0 0.48 9.4 0.1 2.4 2 1 0 2 2 2 0 PUCC protein ExbD PF02472.16 EGR32150.1 - 0.1 12.8 5.3 0.12 12.6 0.1 2.8 3 0 0 3 3 3 0 Biopolymer transport protein ExbD/TolR DUF3784 PF12650.7 EGR32150.1 - 0.26 11.5 0.0 0.26 11.5 0.0 4.8 4 1 2 6 6 6 0 Domain of unknown function (DUF3784) Iron_permease PF04120.12 EGR32150.1 - 0.57 9.9 4.0 0.9 9.3 0.3 2.9 2 1 0 2 2 2 0 Low affinity iron permease HisKA_2 PF07568.12 EGR32150.1 - 0.61 10.2 3.2 12 6.1 0.1 3.1 3 0 0 3 3 3 0 Histidine kinase DUF4231 PF14015.6 EGR32150.1 - 2.5 8.6 5.3 39 4.8 0.1 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) HSBP1 PF06825.12 EGR32151.1 - 2.3e-23 81.8 6.5 3.7e-23 81.1 6.5 1.4 1 0 0 1 1 1 1 Heat shock factor binding protein 1 YgbB PF02542.16 EGR32151.1 - 0.0038 17.5 0.4 0.004 17.5 0.4 1.0 1 0 0 1 1 1 1 YgbB family BLOC1_2 PF10046.9 EGR32151.1 - 0.014 15.7 1.4 0.021 15.1 1.4 1.4 1 1 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 EGR32151.1 - 0.026 14.6 0.2 0.03 14.3 0.2 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Lectin_N PF03954.14 EGR32151.1 - 0.073 12.8 0.5 0.078 12.7 0.5 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF1515 PF07439.11 EGR32151.1 - 0.09 12.8 0.6 0.086 12.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1515) YtxH PF12732.7 EGR32151.1 - 0.18 12.4 0.2 0.26 11.8 0.2 1.3 1 0 0 1 1 1 0 YtxH-like protein MtrB PF05440.12 EGR32151.1 - 0.27 11.7 1.2 0.44 11.0 1.2 1.5 1 1 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B XhlA PF10779.9 EGR32151.1 - 2.4 8.4 5.8 1.6 9.0 1.9 2.2 1 1 1 2 2 2 0 Haemolysin XhlA EF-hand_6 PF13405.6 EGR32152.1 - 2.2e-18 64.5 8.6 0.003 17.4 0.2 7.3 7 0 0 7 7 7 4 EF-hand domain EF-hand_7 PF13499.6 EGR32152.1 - 4.1e-16 59.2 11.3 1.9e-08 34.6 0.6 5.7 5 1 1 6 6 6 4 EF-hand domain pair EF-hand_1 PF00036.32 EGR32152.1 - 1.3e-14 52.6 11.7 0.0091 15.5 0.0 6.5 6 0 0 6 6 6 4 EF hand EF-hand_8 PF13833.6 EGR32152.1 - 8.3e-12 44.8 2.7 5.8e-06 26.1 0.1 4.2 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EGR32152.1 - 0.0021 17.5 0.9 31 4.3 0.0 4.6 4 0 0 4 4 4 0 EF hand Caleosin PF05042.13 EGR32152.1 - 0.024 14.5 6.9 0.34 10.8 0.1 4.0 5 0 0 5 5 5 0 Caleosin related protein Herpes_TAF50 PF03326.13 EGR32152.1 - 0.025 13.3 0.1 0.046 12.4 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Acetyltransf_11 PF13720.6 EGR32152.1 - 0.35 11.4 3.3 0.51 10.8 0.1 2.9 3 0 0 3 3 3 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 EF-hand_4 PF12763.7 EGR32152.1 - 7.4 6.6 13.4 20 5.2 0.1 5.1 3 2 2 6 6 6 0 Cytoskeletal-regulatory complex EF hand Thioredoxin PF00085.20 EGR32155.1 - 5.7e-59 196.5 8.2 9.9e-30 102.6 0.0 4.1 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 EGR32155.1 - 4e-25 88.8 30.8 1.2e-22 80.8 11.2 3.9 3 2 1 4 4 3 3 Thioredoxin-like domain OST3_OST6 PF04756.13 EGR32155.1 - 5.8e-15 55.4 12.1 5.5e-10 39.1 0.1 4.4 1 1 3 4 4 4 3 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EGR32155.1 - 1.1e-07 32.0 0.1 0.0024 18.0 0.0 3.6 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EGR32155.1 - 8e-06 26.3 0.0 8e-06 26.3 0.0 5.1 3 2 1 4 4 3 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGR32155.1 - 0.00052 20.3 19.7 0.08 13.3 0.0 6.5 4 2 3 7 7 7 2 Thioredoxin-like Caldesmon PF02029.15 EGR32155.1 - 0.0012 17.8 47.7 0.0012 17.8 47.7 1.6 2 0 0 2 2 2 1 Caldesmon GAGA_bind PF06217.12 EGR32155.1 - 0.0083 16.4 29.3 0.0083 16.4 29.3 2.0 2 0 0 2 2 2 1 GAGA binding protein-like family DUF4407 PF14362.6 EGR32155.1 - 0.086 12.2 26.3 0.22 10.8 26.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4045 PF13254.6 EGR32155.1 - 1 9.0 33.9 1.7 8.2 33.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) LAP1C PF05609.12 EGR32155.1 - 1.5 7.8 32.3 2.4 7.2 31.1 1.8 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Borrelia_P83 PF05262.11 EGR32155.1 - 7.3 5.0 51.4 15 3.9 51.4 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein ATP-synt PF00231.19 EGR32156.1 - 1.4e-71 241.4 4.9 1.6e-71 241.3 4.9 1.0 1 0 0 1 1 1 1 ATP synthase Ion_trans PF00520.31 EGR32157.1 - 3.3e-11 42.9 8.6 3.3e-11 42.9 8.6 2.2 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 EGR32157.1 - 2.8e-10 40.0 12.0 2.8e-10 40.0 12.0 2.8 2 1 1 3 3 3 1 Ion channel cNMP_binding PF00027.29 EGR32157.1 - 4.2e-10 39.6 0.0 7.6e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain RIFIN PF02009.16 EGR32157.1 - 7.9e-06 26.0 8.8 7.9e-06 26.0 8.8 1.9 2 0 0 2 2 2 1 Rifin Shisa PF13908.6 EGR32157.1 - 0.08 13.2 6.9 2.5 8.3 1.4 3.2 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator Enkurin PF13864.6 EGR32158.1 - 1.8e-21 76.4 11.1 3.8e-21 75.4 11.1 1.5 1 0 0 1 1 1 1 Calmodulin-binding TPX2 PF06886.11 EGR32158.1 - 1.6 9.0 9.2 0.93 9.8 3.3 2.5 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) EFG_IV PF03764.18 EGR32159.1 - 1.4e-24 86.1 0.0 4.3e-24 84.6 0.0 1.8 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EGR32159.1 - 2.3e-21 75.6 0.0 5.3e-21 74.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EGR32159.1 - 5.8e-13 48.7 0.0 1.4e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EGR32159.1 - 6.7e-13 48.8 0.0 1.6e-12 47.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU PF00009.27 EGR32159.1 - 2.2e-07 30.6 0.1 4.6e-07 29.6 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Tyosinase_C PF18132.1 EGR32159.1 - 0.052 14.2 0.0 0.1 13.2 0.0 1.4 1 0 0 1 1 1 0 Tyosinase C-terminal domain RF3_C PF16658.5 EGR32159.1 - 0.075 12.9 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain Pkinase PF00069.25 EGR32160.1 - 3.1e-40 138.2 2.8 3.1e-40 138.2 2.8 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32160.1 - 4.1e-26 91.8 0.5 6e-26 91.3 0.5 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR32160.1 - 1.9e-07 30.7 0.3 2.7e-07 30.2 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGR32160.1 - 0.013 14.8 1.0 0.013 14.8 1.0 2.0 2 1 0 2 2 2 0 Kinase-like APH PF01636.23 EGR32160.1 - 0.07 13.0 0.0 0.83 9.5 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DHHC PF01529.20 EGR32161.1 - 2.5e-33 115.0 19.3 2.5e-33 115.0 19.3 4.6 5 1 1 6 6 6 1 DHHC palmitoyltransferase Ank_5 PF13857.6 EGR32161.1 - 3.9e-20 71.7 0.0 9.2e-09 35.4 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGR32161.1 - 3.2e-16 59.7 7.8 6.3e-09 36.3 1.9 3.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGR32161.1 - 1.2e-15 57.7 0.2 2.4e-06 27.9 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 EGR32161.1 - 1.1e-14 54.1 0.0 2.9e-05 24.3 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EGR32161.1 - 1.1e-13 50.0 1.5 2.5e-05 24.3 0.0 5.4 7 0 0 7 7 7 2 Ankyrin repeat DUF898 PF05987.13 EGR32161.1 - 0.00075 18.6 1.5 0.00075 18.6 1.5 2.2 3 0 0 3 3 3 1 Bacterial protein of unknown function (DUF898) Ribosomal_S8 PF00410.19 EGR32161.1 - 0.12 12.3 0.2 0.12 12.3 0.2 3.8 4 1 2 6 6 6 0 Ribosomal protein S8 DZR PF12773.7 EGR32161.1 - 2.4 8.2 10.8 5.7 7.0 10.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon EF-hand_7 PF13499.6 EGR32162.1 - 3.2e-15 56.3 1.7 6.3e-11 42.6 0.3 2.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR32162.1 - 4.2e-12 45.0 2.7 6.6e-05 22.5 0.1 4.4 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 EGR32162.1 - 5e-12 44.4 5.3 0.00064 19.1 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 EGR32162.1 - 4.9e-07 29.0 6.0 0.012 15.0 0.0 4.3 4 0 0 4 4 4 2 EF hand EF-hand_10 PF14788.6 EGR32162.1 - 5.5e-06 26.1 0.8 0.0019 18.1 0.0 3.7 4 0 0 4 4 4 1 EF hand Dockerin_1 PF00404.18 EGR32162.1 - 0.0027 17.9 2.4 0.31 11.2 0.4 2.9 2 1 1 3 3 3 1 Dockerin type I domain EF-hand_8 PF13833.6 EGR32162.1 - 0.012 15.4 0.8 6.4 6.7 0.1 2.7 1 1 1 2 2 2 0 EF-hand domain pair EF-hand_9 PF14658.6 EGR32162.1 - 0.02 15.2 0.6 2.1 8.7 0.1 3.2 3 0 0 3 3 3 0 EF-hand domain SPARC_Ca_bdg PF10591.9 EGR32162.1 - 0.084 13.2 0.1 0.49 10.7 0.1 2.4 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region PX PF00787.24 EGR32163.1 - 6.2e-18 64.8 4.0 2.2e-17 63.1 4.0 2.0 1 0 0 1 1 1 1 PX domain EF-hand_7 PF13499.6 EGR32164.1 - 7.6e-19 67.9 30.1 2.4e-05 24.7 0.4 7.5 7 2 0 8 8 8 4 EF-hand domain pair EF-hand_6 PF13405.6 EGR32164.1 - 5.7e-18 63.2 30.3 0.015 15.2 0.9 10.7 11 0 0 11 11 11 7 EF-hand domain EF-hand_8 PF13833.6 EGR32164.1 - 1.1e-16 60.5 18.3 5.7e-06 26.1 0.4 6.0 6 1 1 7 7 7 3 EF-hand domain pair EF-hand_1 PF00036.32 EGR32164.1 - 5.9e-12 44.2 30.0 0.027 14.0 0.7 9.7 9 0 0 9 9 9 6 EF hand EF-hand_9 PF14658.6 EGR32164.1 - 0.0008 19.7 0.8 0.047 14.0 0.0 3.6 4 0 0 4 4 4 1 EF-hand domain EF-hand_10 PF14788.6 EGR32164.1 - 0.24 11.3 0.0 0.24 11.3 0.0 4.1 5 0 0 5 5 5 0 EF hand EF-hand_11 PF08976.11 EGR32164.1 - 3.1 8.7 10.7 1.2 10.1 0.3 4.3 5 0 0 5 5 5 0 EF-hand domain MRC1 PF09444.10 EGR32165.1 - 0.00079 20.0 7.8 0.00094 19.7 7.8 1.1 1 0 0 1 1 1 1 MRC1-like domain Tweety PF04906.13 EGR32165.1 - 0.004 15.9 0.1 0.0051 15.5 0.1 1.1 1 0 0 1 1 1 1 Tweety Peptidase_M8 PF01457.16 EGR32166.1 - 2.3e-38 132.2 12.3 6e-35 120.9 0.2 2.1 1 1 1 2 2 2 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR32166.1 - 0.00033 20.6 3.8 0.0011 19.0 3.8 2.0 1 0 0 1 1 1 1 Tenascin EGF domain EGF_2 PF07974.13 EGR32166.1 - 0.0016 18.8 10.5 0.0016 18.8 10.5 3.7 5 1 0 5 5 5 1 EGF-like domain Zincin_1 PF06262.11 EGR32166.1 - 0.14 12.3 0.1 0.35 11.0 0.1 1.6 1 0 0 1 1 1 0 Zincin-like metallopeptidase Transketolase_N PF00456.21 EGR32167.1 - 2.1e-10 40.1 0.0 2.9e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain TCR PF03638.15 EGR32168.1 - 9.2e-22 77.1 61.4 2.2e-12 47.1 23.4 2.9 2 1 1 3 3 3 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain Cyclin_N PF00134.23 EGR32169.1 - 3.2e-08 33.3 2.6 3.2e-08 33.3 2.6 3.5 3 1 0 3 3 3 1 Cyclin, N-terminal domain TFIIB PF00382.19 EGR32169.1 - 0.0027 17.7 0.1 1.4 9.0 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat RINGv PF12906.7 EGR32170.1 - 4.6e-10 39.5 15.7 9.5e-10 38.4 15.7 1.6 1 0 0 1 1 1 1 RING-variant domain FHA PF00498.26 EGR32170.1 - 6.2e-10 39.3 0.2 2.4e-09 37.4 0.2 2.0 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGR32170.1 - 7.1e-07 29.5 0.0 2e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain UQ_con PF00179.26 EGR32171.1 - 1e-28 99.7 0.0 1.2e-28 99.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGR32171.1 - 0.0043 17.3 0.3 0.0072 16.6 0.3 1.5 1 1 0 1 1 1 1 RWD domain UFC1 PF08694.11 EGR32171.1 - 0.011 15.4 0.1 0.017 14.8 0.1 1.5 1 1 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 CPG4 PF15481.6 EGR32172.1 - 0.043 14.4 5.6 0.065 13.9 5.6 1.3 1 0 0 1 1 1 0 Chondroitin proteoglycan 4 DUF3575 PF12099.8 EGR32172.1 - 0.056 12.7 0.2 0.066 12.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3575) RCC1 PF00415.18 EGR32173.1 - 5.2e-95 311.9 6.7 3.1e-14 53.3 0.4 7.1 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR32173.1 - 6e-48 159.8 20.7 6.1e-08 32.3 0.1 8.3 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.14 EGR32173.1 - 2.5e-12 46.5 0.3 0.084 12.7 0.0 6.1 5 2 1 6 6 6 3 Peptidase family C25, C terminal ig-like domain FTP PF07504.13 EGR32173.1 - 0.00021 21.0 1.3 0.065 13.1 0.0 3.9 3 0 0 3 3 3 1 Fungalysin/Thermolysin Propeptide Motif Hira PF07569.11 EGR32173.1 - 0.011 15.5 0.0 3.2 7.4 0.0 3.8 4 0 0 4 4 4 0 TUP1-like enhancer of split IceA2 PF05862.11 EGR32173.1 - 0.032 14.2 0.4 1.7 8.6 0.0 3.3 4 0 0 4 4 4 0 Helicobacter pylori IceA2 protein MliC PF09864.9 EGR32173.1 - 0.042 13.8 0.9 5.5 7.0 0.0 4.0 4 0 0 4 4 4 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme DUF5074 PF16819.5 EGR32173.1 - 0.057 13.5 1.4 4.3 7.4 0.0 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5074) SUKH-3 PF14433.6 EGR32173.1 - 0.077 13.5 1.8 1.1e+02 3.2 0.0 4.5 5 0 0 5 5 5 0 SUKH-3 immunity protein PapC_C PF13953.6 EGR32173.1 - 0.11 12.3 4.2 72 3.3 0.0 4.9 5 0 0 5 5 5 0 PapC C-terminal domain Mistic PF11458.8 EGR32174.1 - 0.19 11.7 6.3 4 7.5 3.6 2.4 2 0 0 2 2 2 0 Membrane-integrating protein Mistic HATPase_c PF02518.26 EGR32175.1 - 1.4e-22 80.3 0.0 3.8e-22 78.9 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGR32175.1 - 1.5e-05 24.9 0.2 2.7e-05 24.1 0.2 1.5 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EGR32175.1 - 0.0051 16.6 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGR32175.1 - 0.045 13.9 1.3 5.8 7.1 0.1 3.1 2 1 1 3 3 3 0 Response regulator receiver domain Ion_trans PF00520.31 EGR32179.1 - 2e-07 30.5 12.1 3.5e-07 29.7 12.1 1.4 1 0 0 1 1 1 1 Ion transport protein DPM3 PF08285.11 EGR32179.1 - 0.6 10.3 6.1 0.19 11.9 0.4 2.4 2 0 0 2 2 2 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) EF-hand_7 PF13499.6 EGR32180.1 - 2.3e-21 76.0 37.5 2.3e-07 31.2 0.7 7.6 5 3 0 6 6 6 6 EF-hand domain pair EF-hand_6 PF13405.6 EGR32180.1 - 2.6e-21 73.6 41.0 4.8e-05 23.0 0.3 10.5 10 0 0 10 10 10 7 EF-hand domain EF-hand_8 PF13833.6 EGR32180.1 - 4.3e-17 61.7 23.9 1.3e-06 28.1 0.1 8.3 5 3 3 8 8 8 6 EF-hand domain pair EF-hand_1 PF00036.32 EGR32180.1 - 6e-17 59.9 45.1 1.8e-06 27.1 0.9 9.7 10 0 0 10 10 10 6 EF hand EF-hand_5 PF13202.6 EGR32180.1 - 7.3e-06 25.2 33.5 0.016 14.7 1.5 6.0 6 0 0 6 6 6 4 EF hand EF-hand_11 PF08976.11 EGR32180.1 - 6e-05 23.9 9.7 0.014 16.3 0.1 3.9 2 1 1 3 3 3 2 EF-hand domain Sacchrp_dh_NADP PF03435.18 EGR32180.1 - 0.048 13.9 0.2 0.1 12.8 0.2 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain EF-hand_9 PF14658.6 EGR32180.1 - 0.084 13.2 0.4 50 4.3 0.0 4.5 5 0 0 5 5 5 0 EF-hand domain Pkinase PF00069.25 EGR32181.1 - 1.2e-23 83.8 5.4 1.9e-23 83.2 5.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32181.1 - 2.1e-15 56.7 0.8 2.6e-15 56.4 0.8 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Elf4 PF07011.11 EGR32181.1 - 0.0063 16.4 1.6 0.015 15.2 0.2 2.0 2 0 0 2 2 2 1 Early Flowering 4 domain Kdo PF06293.14 EGR32181.1 - 0.0077 15.6 0.1 0.012 15.0 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_7 PF13499.6 EGR32182.1 - 4.3e-25 88.0 40.2 6.1e-06 26.6 1.4 9.1 8 0 0 8 8 8 7 EF-hand domain pair EF-hand_6 PF13405.6 EGR32182.1 - 7.1e-25 84.8 45.1 2.2e-05 24.0 0.2 11.8 11 0 0 11 11 11 6 EF-hand domain EF-hand_1 PF00036.32 EGR32182.1 - 9.5e-25 84.3 45.8 4.7e-06 25.8 0.2 11.4 11 0 0 11 11 11 7 EF hand HU-CCDC81_euk_1 PF14908.6 EGR32182.1 - 7.6e-22 77.3 0.1 4.9e-21 74.7 0.1 2.6 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 EF-hand_8 PF13833.6 EGR32182.1 - 1.1e-13 50.9 36.1 1.7e-05 24.6 0.1 10.1 10 1 0 10 10 10 7 EF-hand domain pair HU-CCDC81_euk_2 PF18289.1 EGR32182.1 - 1.5e-13 50.7 0.0 6.7e-12 45.4 0.0 3.2 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 2 EF-hand_5 PF13202.6 EGR32182.1 - 9.5e-11 40.7 32.5 0.0023 17.3 0.1 8.0 8 0 0 8 8 8 4 EF hand EF-hand_13 PF17958.1 EGR32182.1 - 0.046 13.5 2.6 11 5.9 0.1 4.7 4 1 1 5 5 5 0 EF-hand domain Type_III_YscX PF09474.10 EGR32182.1 - 0.25 11.6 1.2 22 5.4 0.1 2.7 2 0 0 2 2 2 0 Type III secretion system YscX (type_III_YscX) EF-hand_9 PF14658.6 EGR32182.1 - 1.9 8.9 9.0 5.4 7.4 0.0 6.1 8 1 0 8 8 8 0 EF-hand domain Beach PF02138.18 EGR32183.1 - 2.5e-71 240.3 5.6 3.3e-71 239.9 5.6 1.1 1 0 0 1 1 1 1 Beige/BEACH domain DSPc PF00782.20 EGR32183.1 - 1.9e-07 31.0 1.6 1.9e-07 31.0 1.6 2.8 3 1 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Pkinase PF00069.25 EGR32184.1 - 5.2e-42 144.0 2.0 5.2e-42 144.0 2.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32184.1 - 1.4e-24 86.8 0.7 1.4e-24 86.8 0.7 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EGR32184.1 - 0.074 13.0 0.2 0.6 10.0 0.1 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family Mito_carr PF00153.27 EGR32185.1 - 1.3e-55 185.3 2.6 1.8e-19 69.4 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein SET PF00856.28 EGR32186.1 - 4.5e-08 33.7 0.4 9.9e-08 32.6 0.1 1.8 2 0 0 2 2 2 1 SET domain MT-A70 PF05063.14 EGR32187.1 - 1.7e-42 145.2 0.1 2.9e-42 144.5 0.1 1.4 1 0 0 1 1 1 1 MT-A70 DUF562 PF04763.12 EGR32187.1 - 0.23 10.9 1.2 1.9 7.9 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF562) LMBR1 PF04791.16 EGR32187.1 - 2.7 6.8 5.3 3.4 6.4 5.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein WD40 PF00400.32 EGR32188.1 - 2.8e-05 24.8 2.0 1 10.4 0.1 4.8 5 0 0 5 5 5 2 WD domain, G-beta repeat FmdE PF02663.14 EGR32188.1 - 0.023 14.8 0.8 0.054 13.5 0.0 2.0 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon DUF2228 PF10228.9 EGR32188.1 - 1.6 8.4 4.5 0.38 10.5 0.1 2.1 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2228) WD40 PF00400.32 EGR32189.1 - 0.0034 18.2 0.2 0.011 16.5 0.1 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat UPF0154 PF03672.13 EGR32189.1 - 0.016 15.2 0.1 0.033 14.2 0.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) EF-hand_6 PF13405.6 EGR32189.1 - 0.089 12.8 0.0 0.36 10.9 0.0 2.1 1 1 0 1 1 1 0 EF-hand domain SF-assemblin PF06705.11 EGR32190.1 - 2.7e-05 23.6 44.2 0.0026 17.2 30.4 3.4 1 1 2 3 3 3 3 SF-assemblin/beta giardin MerR-DNA-bind PF09278.11 EGR32190.1 - 0.066 13.8 5.7 1.7 9.2 2.8 3.4 2 1 0 2 2 2 0 MerR, DNA binding ApoO PF09769.9 EGR32190.1 - 0.26 11.2 7.0 3.8 7.5 0.1 2.7 1 1 2 3 3 3 0 Apolipoprotein O DUF1730 PF08331.10 EGR32190.1 - 0.3 11.0 1.1 2.2 8.2 0.2 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF1730) PIN_8 PF18476.1 EGR32190.1 - 1.8 8.4 30.3 0.08 12.8 13.0 3.2 1 1 3 4 4 4 0 PIN like domain DUF4407 PF14362.6 EGR32190.1 - 3.5 6.9 23.8 0.36 10.1 9.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) IF-2B PF01008.17 EGR32190.1 - 5.4 6.1 15.6 0.12 11.6 5.9 2.2 1 1 0 2 2 2 0 Initiation factor 2 subunit family PepSY_TM_like_2 PF16357.5 EGR32190.1 - 8.6 6.3 14.1 0.11 12.5 3.4 2.3 1 1 1 2 2 2 0 Putative PepSY_TM-like ATP-synt_ab PF00006.25 EGR32191.1 - 2.7e-72 242.9 0.0 4.5e-72 242.2 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 EGR32191.1 - 4.2e-49 166.1 1.4 8e-49 165.1 1.4 1.5 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.23 EGR32191.1 - 1.1e-16 61.1 3.9 2.8e-16 59.8 3.9 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.10 EGR32191.1 - 3e-05 24.1 1.8 7.9e-05 22.7 1.8 1.7 1 0 0 1 1 1 1 HAS barrel domain AAA_28 PF13521.6 EGR32192.1 - 3.1e-21 76.3 0.0 4.6e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGR32192.1 - 1.3e-05 25.0 0.0 2.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Thymidylate kinase KTI12 PF08433.10 EGR32192.1 - 0.003 17.1 0.0 0.016 14.6 0.0 2.2 1 1 1 2 2 2 1 Chromatin associated protein KTI12 AAA_18 PF13238.6 EGR32192.1 - 0.0042 17.6 0.1 0.23 12.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EGR32192.1 - 0.033 14.1 0.1 0.078 12.9 0.1 1.6 1 0 0 1 1 1 0 NTPase T2SSE PF00437.20 EGR32192.1 - 0.14 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein WD40 PF00400.32 EGR32194.1 - 2e-25 88.5 0.3 3.7e-09 37.1 0.0 5.5 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR32194.1 - 5.7e-11 42.6 0.8 0.0011 19.2 0.0 4.6 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain SR-25 PF10500.9 EGR32194.1 - 3.2 7.3 12.1 0.62 9.6 6.1 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein CCB1 PF12046.8 EGR32195.1 - 0.072 12.4 4.0 0.16 11.3 0.3 2.1 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B C2-C2_1 PF11618.8 EGR32196.1 - 1.4e-39 135.4 0.3 8.7e-38 129.6 0.3 2.9 2 1 0 2 2 2 1 First C2 domain of RPGR-interacting protein 1 EF-hand_1 PF00036.32 EGR32196.1 - 6.2e-27 91.1 30.4 3.7e-06 26.1 0.2 7.9 6 1 1 7 7 7 6 EF hand EF-hand_6 PF13405.6 EGR32196.1 - 3.1e-26 89.0 27.5 2.2e-05 24.0 0.8 8.7 8 1 1 9 9 9 6 EF-hand domain EF-hand_7 PF13499.6 EGR32196.1 - 5.9e-26 90.7 28.5 1.6e-11 44.4 1.8 5.9 4 3 2 6 6 6 4 EF-hand domain pair EF-hand_8 PF13833.6 EGR32196.1 - 5.8e-18 64.5 20.3 5.6e-11 42.1 0.7 6.3 4 2 2 6 6 6 5 EF-hand domain pair EF-hand_5 PF13202.6 EGR32196.1 - 1e-11 43.8 23.8 0.00027 20.3 0.2 7.2 7 0 0 7 7 7 5 EF hand SPARC_Ca_bdg PF10591.9 EGR32196.1 - 4.1e-07 30.3 16.6 0.00033 20.9 0.7 4.3 4 0 0 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EGR32196.1 - 0.0064 17.4 8.5 0.048 14.5 0.6 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_4 PF12763.7 EGR32196.1 - 0.35 10.8 17.6 0.26 11.2 0.2 4.2 5 0 0 5 5 5 0 Cytoskeletal-regulatory complex EF hand TerB PF05099.13 EGR32196.1 - 2.2 8.3 9.7 9 6.2 0.0 3.8 4 0 0 4 4 4 0 Tellurite resistance protein TerB DUF3456 PF11938.8 EGR32196.1 - 4.7 7.7 12.9 2.6 8.5 4.4 2.9 2 1 0 2 2 2 0 TLR4 regulator and MIR-interacting MSAP Patatin PF01734.22 EGR32197.1 - 0.0024 18.1 0.0 0.0037 17.5 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase EF-hand_7 PF13499.6 EGR32198.1 - 2.1e-31 108.1 54.0 1.5e-12 47.7 0.6 9.1 6 1 4 10 10 10 6 EF-hand domain pair EF-hand_8 PF13833.6 EGR32198.1 - 1.3e-29 101.8 25.4 4.2e-09 36.1 0.6 7.2 6 1 0 6 6 6 4 EF-hand domain pair EF-hand_1 PF00036.32 EGR32198.1 - 6.8e-29 97.2 46.4 3.3e-07 29.4 0.3 9.1 8 0 0 8 8 8 5 EF hand EF-hand_6 PF13405.6 EGR32198.1 - 2e-28 95.8 45.8 1e-05 25.0 0.2 10.8 12 0 0 12 12 12 7 EF-hand domain EF-hand_5 PF13202.6 EGR32198.1 - 5.4e-23 79.4 32.0 9.6e-06 24.9 0.5 8.1 7 0 0 7 7 7 5 EF hand SPARC_Ca_bdg PF10591.9 EGR32198.1 - 3.8e-05 24.0 27.9 0.027 14.8 0.2 7.1 5 1 1 6 6 6 3 Secreted protein acidic and rich in cysteine Ca binding region MgtE_N PF03448.17 EGR32198.1 - 0.0038 17.8 0.7 0.56 10.8 0.0 3.8 3 0 0 3 3 3 1 MgtE intracellular N domain EF-hand_9 PF14658.6 EGR32198.1 - 0.027 14.8 7.1 0.46 10.8 0.1 4.7 6 0 0 6 6 6 0 EF-hand domain DUF4734 PF15881.5 EGR32198.1 - 0.033 14.4 4.0 0.13 12.5 0.0 4.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4734) DUF3349 PF11829.8 EGR32198.1 - 0.077 13.8 1.1 0.85 10.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3349) EF-hand_7 PF13499.6 EGR32199.1 - 2.3e-27 95.2 14.0 9.6e-12 45.2 1.4 5.7 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_1 PF00036.32 EGR32199.1 - 2.2e-17 61.2 28.0 1.1e-07 30.8 0.8 6.8 7 0 0 7 7 7 5 EF hand EF-hand_6 PF13405.6 EGR32199.1 - 3.1e-16 57.8 25.2 0.00013 21.6 0.2 8.1 9 0 0 9 9 9 5 EF-hand domain EF-hand_8 PF13833.6 EGR32199.1 - 2.1e-11 43.5 5.3 0.00022 21.0 0.5 4.9 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EGR32199.1 - 3.6e-09 35.7 15.4 7e-05 22.1 0.1 6.0 6 0 0 6 6 6 3 EF hand EF-hand_9 PF14658.6 EGR32199.1 - 2.2e-08 34.3 0.1 0.00018 21.8 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EGR32199.1 - 0.0057 17.0 0.8 0.0057 17.0 0.8 3.6 3 1 1 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region DUF3750 PF12570.8 EGR32199.1 - 0.14 12.8 0.1 0.64 10.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3750) EF-hand_14 PF17959.1 EGR32199.1 - 1.2 9.6 8.0 0.47 10.8 0.8 3.7 3 1 1 4 4 4 0 EF-hand domain EF-hand_4 PF12763.7 EGR32199.1 - 8.8 6.3 13.5 1.1 9.2 2.6 3.9 3 1 1 5 5 5 0 Cytoskeletal-regulatory complex EF hand Pkinase PF00069.25 EGR32201.1 - 1e-70 238.1 0.2 1.3e-70 237.8 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32201.1 - 2.8e-39 134.9 0.0 3.9e-39 134.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR32201.1 - 9.9e-05 21.8 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGR32201.1 - 0.0013 17.8 0.4 0.0013 17.8 0.4 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EGR32201.1 - 0.0017 17.7 0.1 0.0033 16.8 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR32201.1 - 0.0018 17.2 0.0 0.0028 16.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EGR32201.1 - 0.041 12.9 0.5 0.06 12.4 0.5 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 PhoLip_ATPase_N PF16209.5 EGR32202.1 - 3.4e-23 81.1 4.6 3.4e-23 81.1 4.6 2.6 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal PhoLip_ATPase_C PF16212.5 EGR32202.1 - 6.3e-23 81.8 7.1 6.3e-23 81.8 7.1 3.8 3 1 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EGR32202.1 - 3.3e-12 47.2 0.2 1.8e-05 25.1 0.1 3.6 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGR32202.1 - 1.3e-09 38.0 0.0 6.7e-09 35.7 0.0 2.2 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGR32202.1 - 1.6e-06 27.8 0.0 6.9e-06 25.7 0.0 2.1 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGR32202.1 - 0.022 14.5 0.5 0.022 14.5 0.5 4.6 3 1 0 4 4 4 0 haloacid dehalogenase-like hydrolase DEAD PF00270.29 EGR32203.1 - 1.1e-37 129.5 0.7 6.7e-37 126.9 0.2 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR32203.1 - 1.2e-20 73.9 0.5 1.3e-19 70.6 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGR32203.1 - 5.4e-11 42.5 0.1 1.7e-10 41.0 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGR32203.1 - 5.4e-07 29.8 0.2 1.4e-06 28.5 0.2 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CTK3 PF12243.8 EGR32203.1 - 0.013 15.4 0.8 0.038 14.0 0.8 1.7 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 Proteasome PF00227.26 EGR32205.1 - 3.6e-45 153.8 0.4 4.4e-45 153.5 0.4 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGR32205.1 - 1.4e-11 43.8 0.0 3.1e-11 42.7 0.0 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF1746 PF08508.10 EGR32205.1 - 0.081 13.3 0.0 0.39 11.1 0.0 2.0 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1746) V-ATPase_H_C PF11698.8 EGR32209.1 - 1.6e-40 137.9 1.2 1.6e-40 137.9 1.2 1.7 1 1 1 2 2 2 1 V-ATPase subunit H V-ATPase_H_N PF03224.14 EGR32209.1 - 1.9e-10 40.6 2.3 1.9e-10 40.6 2.3 1.8 2 0 0 2 2 2 1 V-ATPase subunit H HEAT PF02985.22 EGR32209.1 - 0.014 15.6 0.7 0.17 12.2 0.0 2.8 3 0 0 3 3 3 0 HEAT repeat Cyt-b5 PF00173.28 EGR32209.1 - 0.015 15.4 0.0 0.033 14.4 0.0 1.6 1 0 0 1 1 1 0 Cytochrome b5-like Heme/Steroid binding domain Arm PF00514.23 EGR32209.1 - 0.043 13.9 0.3 6.3 7.0 0.0 2.7 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGR32209.1 - 0.049 14.2 0.1 20 5.8 0.0 3.0 3 0 0 3 3 3 0 HEAT-like repeat EAP30 PF04157.16 EGR32209.1 - 0.12 11.7 0.5 0.31 10.3 0.2 1.7 1 1 1 2 2 2 0 EAP30/Vps36 family PFO_beta_C PF12367.8 EGR32209.1 - 0.12 12.5 0.7 0.37 11.0 0.3 1.9 2 0 0 2 2 2 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal ERCC4 PF02732.15 EGR32211.1 - 0.12 12.6 6.9 0.14 12.3 6.9 1.1 1 0 0 1 1 1 0 ERCC4 domain DUF2353 PF09789.9 EGR32212.1 - 1.6e-06 27.8 27.2 1.7e-06 27.6 27.2 1.1 1 0 0 1 1 1 1 Uncharacterized coiled-coil protein (DUF2353) CENP-F_leu_zip PF10473.9 EGR32212.1 - 0.068 13.2 35.3 0.099 12.7 11.5 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GAS PF13851.6 EGR32212.1 - 0.2 11.0 39.1 0.73 9.1 22.0 2.1 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Cep57_CLD_2 PF14197.6 EGR32212.1 - 1.5 8.9 22.9 1.9 8.6 5.7 3.4 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 UPF0242 PF06785.11 EGR32212.1 - 2.4 8.2 40.7 3 7.9 13.5 3.1 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus Rootletin PF15035.6 EGR32212.1 - 3.3 7.7 25.4 2.7 8.0 24.1 1.5 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion Jnk-SapK_ap_N PF09744.9 EGR32212.1 - 3.3 7.9 34.4 2.1 8.6 28.6 2.1 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Leu_zip PF15294.6 EGR32212.1 - 4.7 6.6 35.0 6.4 6.2 22.9 2.3 1 1 1 2 2 2 0 Leucine zipper Cep57_MT_bd PF06657.13 EGR32212.1 - 5.5 7.5 24.3 0.2 12.1 11.6 2.5 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 ATG16 PF08614.11 EGR32212.1 - 7.6 6.7 29.0 0.22 11.7 20.1 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Pkinase PF00069.25 EGR32213.1 - 7.8e-38 130.3 2.3 1e-37 129.9 2.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32213.1 - 3.5e-15 56.0 0.2 5e-15 55.5 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR32213.1 - 1.5e-05 24.0 0.2 2.3e-05 23.3 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGR32213.1 - 0.0014 18.0 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR32213.1 - 0.097 12.0 0.9 0.15 11.4 0.9 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_60s PF00428.19 EGR32215.1 - 1.4e-12 48.0 6.0 1.7e-12 47.7 6.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Ribosomal_S21e PF01249.18 EGR32216.1 - 1e-28 99.2 0.0 1.2e-28 99.0 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S21e IBN_N PF03810.19 EGR32217.1 - 5.6e-07 29.4 0.3 5.6e-07 29.4 0.3 3.5 3 0 0 3 3 3 1 Importin-beta N-terminal domain HEAT PF02985.22 EGR32217.1 - 2e-06 27.6 0.0 15 6.2 0.0 5.9 6 0 0 6 6 6 3 HEAT repeat TAF6_C PF07571.13 EGR32217.1 - 0.0072 16.6 1.9 2.3 8.6 0.0 4.3 3 1 1 4 4 4 1 TAF6 C-terminal HEAT repeat domain HEAT_2 PF13646.6 EGR32217.1 - 0.012 15.9 0.0 1.8 9.0 0.0 3.7 4 1 0 4 4 4 0 HEAT repeats DUF2811 PF10929.8 EGR32217.1 - 1.4 9.3 4.8 1.2 9.4 0.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2811) RCC1 PF00415.18 EGR32219.1 - 3.7e-32 110.7 14.3 1.2e-11 45.0 0.0 6.4 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR32219.1 - 5.8e-20 70.6 16.9 4.8e-07 29.4 1.9 5.5 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.14 EGR32219.1 - 0.0019 18.0 0.4 2.6 8.0 0.0 3.6 4 1 0 4 4 4 2 Peptidase family C25, C terminal ig-like domain DUF370 PF04025.12 EGR32219.1 - 0.08 13.1 0.0 0.43 10.7 0.0 2.3 1 0 0 1 1 1 0 Domain of unknown function (DUF370) Kelch_2 PF07646.15 EGR32219.1 - 0.44 10.6 6.1 4.1 7.5 0.2 3.8 4 0 0 4 4 4 0 Kelch motif MORN PF02493.20 EGR32220.1 - 1.9e-08 33.7 3.8 1.9e-08 33.7 3.8 3.2 3 0 0 3 3 3 1 MORN repeat DUF2207 PF09972.9 EGR32221.1 - 0.12 11.1 7.1 0.15 10.8 7.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1043 PF06295.12 EGR32221.1 - 0.98 9.4 10.3 1.5 8.9 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) Orf78 PF06024.12 EGR32221.1 - 1.5 9.2 13.1 0.21 11.9 6.3 2.4 1 1 1 2 2 2 0 Orf78 (ac78) cNMP_binding PF00027.29 EGR32222.1 - 1.5e-19 69.8 0.0 3.5e-08 33.4 0.0 3.2 1 1 1 2 2 2 2 Cyclic nucleotide-binding domain CdiA_C_tRNase PF18664.1 EGR32222.1 - 0.047 13.9 4.8 0.1 12.8 2.9 2.3 2 0 0 2 2 2 0 CdiA C-terminal tRNase domain DUF3657 PF12394.8 EGR32222.1 - 0.24 12.0 3.5 2 9.1 0.6 3.0 2 0 0 2 2 2 0 Protein FAM135 SHIPPO-rpt PF07004.12 EGR32225.1 - 0.83 10.7 9.7 27 5.9 0.1 4.6 4 0 0 4 4 4 0 Sperm-tail PG-rich repeat RCC1 PF00415.18 EGR32226.1 - 5.4e-18 65.4 0.5 1.1e-06 29.1 0.0 3.3 3 1 0 3 3 3 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR32226.1 - 3.4e-05 23.5 6.7 0.0086 15.9 0.0 2.9 2 1 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat DUF2237 PF09996.9 EGR32227.1 - 5.3e-24 84.4 0.9 1.4e-13 50.8 0.1 2.0 1 1 1 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2237) PmrD PF11183.8 EGR32227.1 - 0.062 13.4 0.0 0.095 12.8 0.0 1.4 1 0 0 1 1 1 0 Polymyxin resistance protein PmrD Copine PF07002.16 EGR32228.1 - 2.5e-11 43.5 0.0 3.7e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Copine DUF2726 PF10881.8 EGR32228.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) Pkinase PF00069.25 EGR32229.1 - 7.6e-62 209.1 2.7 7.6e-62 209.1 2.7 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32229.1 - 2.8e-41 141.5 0.5 4.4e-41 140.9 0.5 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR32229.1 - 1.1e-10 41.3 0.3 1.1e-10 41.3 0.3 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR32229.1 - 0.00043 19.2 0.0 0.0013 17.6 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGR32229.1 - 0.0062 15.9 0.2 0.012 15.0 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGR32229.1 - 0.018 14.7 2.2 2.5 7.7 0.2 2.5 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 CDC50 PF03381.15 EGR32230.1 - 4.7e-52 177.2 0.7 4.7e-52 177.2 0.7 1.5 1 1 1 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF202 PF02656.15 EGR32230.1 - 0.15 12.5 1.7 9 6.8 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF202) PI3K_C2 PF00792.24 EGR32231.1 - 0.0057 16.6 1.6 0.23 11.3 0.0 3.5 3 1 0 3 3 3 1 Phosphoinositide 3-kinase C2 RSN1_7TM PF02714.15 EGR32232.1 - 4.4e-16 59.0 43.9 8.8e-14 51.5 43.9 2.1 1 1 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate PerB PF06590.11 EGR32234.1 - 0.067 13.7 1.3 0.095 13.2 1.3 1.3 1 0 0 1 1 1 0 PerB protein Cyclin PF08613.11 EGR32235.1 - 1.5e-32 113.2 2.9 1.8e-32 113.0 2.9 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EGR32235.1 - 1e-09 38.2 0.7 1.6e-09 37.6 0.7 1.4 1 1 0 1 1 1 1 Cyclin, N-terminal domain PH_16 PF17838.1 EGR32235.1 - 0.053 13.4 0.7 0.27 11.1 0.3 2.0 1 1 1 2 2 2 0 PH domain Pkinase PF00069.25 EGR32236.1 - 1.4e-62 211.4 0.6 1.4e-62 211.4 0.6 2.4 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32236.1 - 4.2e-26 91.8 0.1 7.5e-26 91.0 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR32236.1 - 0.00092 18.1 0.9 0.0019 17.0 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGR32236.1 - 0.0027 17.1 0.2 0.011 15.1 0.2 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR32236.1 - 0.02 14.8 0.0 0.1 12.5 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Mito_fiss_Elm1 PF06258.11 EGR32236.1 - 0.2 10.8 0.8 0.33 10.1 0.8 1.3 1 0 0 1 1 1 0 Mitochondrial fission ELM1 Pkinase PF00069.25 EGR32237.1 - 2.6e-58 197.5 0.1 2.6e-58 197.5 0.1 1.8 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32237.1 - 1.3e-34 119.7 0.0 4.9e-33 114.5 0.0 2.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR32237.1 - 1.2e-11 44.5 0.0 3.2e-11 43.1 0.0 1.8 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR32237.1 - 0.00012 21.0 2.2 0.00026 19.9 0.0 2.3 3 0 0 3 3 3 1 Fungal protein kinase FTA2 PF13095.6 EGR32237.1 - 0.016 14.8 3.8 1.2 8.7 0.0 2.9 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 SUKH_5 PF14567.6 EGR32237.1 - 0.02 14.6 1.5 0.1 12.3 0.4 2.2 1 1 0 2 2 2 0 SMI1-KNR4 cell-wall APH PF01636.23 EGR32237.1 - 0.05 13.5 0.0 0.25 11.2 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Peptidase_M8 PF01457.16 EGR32238.1 - 2.7e-22 79.2 15.5 6.9e-21 74.5 0.3 2.7 2 1 1 3 3 3 2 Leishmanolysin IMS PF00817.20 EGR32239.1 - 4.9e-46 156.4 0.9 1.4e-45 154.9 0.1 2.0 2 0 0 2 2 2 1 impB/mucB/samB family IMS_HHH PF11798.8 EGR32239.1 - 2.5e-07 30.6 0.2 6.7e-07 29.3 0.2 1.8 1 0 0 1 1 1 1 IMS family HHH motif IMS_C PF11799.8 EGR32239.1 - 5.6e-05 23.8 0.1 0.00018 22.2 0.1 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain DUF4239 PF14023.6 EGR32239.1 - 0.22 11.2 2.5 0.33 10.6 1.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4239) Kinesin PF00225.23 EGR32241.1 - 1.1e-85 287.5 11.9 1.8e-85 286.8 11.9 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR32241.1 - 2.3e-19 69.8 2.7 2.3e-19 69.8 2.7 3.0 4 0 0 4 4 4 1 Microtubule binding T2SSE PF00437.20 EGR32241.1 - 0.019 14.1 0.1 0.065 12.3 0.0 1.9 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.6 EGR32241.1 - 0.031 14.6 0.0 0.11 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGR32241.1 - 0.032 14.6 0.0 0.061 13.7 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain ResIII PF04851.15 EGR32241.1 - 1.7 8.6 9.9 0.052 13.5 0.9 2.8 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit NID PF07292.13 EGR32241.1 - 2 9.1 5.3 8.8 7.0 0.3 3.1 3 0 0 3 3 3 0 Nmi/IFP 35 domain (NID) HA2 PF04408.23 EGR32242.1 - 1.8e-23 82.8 0.0 3.9e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGR32242.1 - 1.2e-13 51.3 0.1 5.7e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGR32242.1 - 0.00038 20.3 0.1 0.00086 19.1 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase ArsR PF09824.9 EGR32242.1 - 0.029 14.0 0.4 0.092 12.3 0.2 1.8 1 1 0 2 2 2 0 ArsR transcriptional regulator ResIII PF04851.15 EGR32242.1 - 0.035 14.1 0.0 0.079 13.0 0.0 1.6 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGR32242.1 - 0.053 13.8 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain WavE PF07507.11 EGR32242.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 WavE lipopolysaccharide synthesis Decorin_bind PF02352.15 EGR32242.1 - 0.15 12.3 1.3 0.27 11.5 0.1 2.1 3 0 0 3 3 3 0 Decorin binding protein OB_NTP_bind PF07717.16 EGR32243.1 - 4.6e-17 62.1 0.0 6e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Kelch_4 PF13418.6 EGR32244.1 - 2e-28 98.1 0.2 1.2e-07 31.7 0.0 5.5 5 0 0 5 5 5 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EGR32244.1 - 3.6e-17 61.9 0.0 0.00056 19.8 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 EGR32244.1 - 1.2e-14 54.2 0.0 0.00014 22.0 0.0 5.7 6 1 0 6 6 6 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EGR32244.1 - 1.1e-10 41.4 0.0 0.16 12.3 0.0 4.8 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 EGR32244.1 - 2.6e-08 33.3 0.0 0.0013 18.3 0.0 4.8 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 EGR32244.1 - 3.2e-06 26.9 0.3 2.4 8.3 0.0 4.9 5 0 0 5 5 5 2 Kelch motif PRKCSH PF07915.13 EGR32244.1 - 8.4 7.5 11.3 22 6.2 0.0 3.0 2 0 0 2 2 2 0 Glucosidase II beta subunit-like protein CPBP PF02517.16 EGR32245.1 - 0.28 11.6 1.8 7.6 7.0 1.8 2.0 1 1 0 1 1 1 0 CPBP intramembrane metalloprotease SHIPPO-rpt PF07004.12 EGR32246.1 - 1.9e-16 60.1 29.4 0.81 10.7 0.0 11.3 11 0 0 11 11 11 8 Sperm-tail PG-rich repeat ECR1_N PF14382.6 EGR32246.1 - 0.002 17.9 0.1 29 4.6 0.0 5.2 7 0 0 7 7 7 2 Exosome complex exonuclease RRP4 N-terminal region CAF1C_H4-bd PF12265.8 EGR32247.1 - 5.6e-15 55.4 3.2 3.6e-14 52.7 1.2 3.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGR32247.1 - 2.4e-14 53.5 4.0 0.0051 17.6 0.2 4.5 4 0 0 4 4 4 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR32247.1 - 9.9e-07 29.0 0.4 0.098 13.0 0.0 4.4 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Adap_comp_sub PF00928.21 EGR32248.1 - 1.5e-15 57.3 6.9 3.1e-15 56.3 6.9 1.5 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGR32248.1 - 0.0022 17.9 2.0 0.0022 17.9 2.0 2.0 2 0 0 2 2 2 1 Clathrin adaptor complex small chain AAA PF00004.29 EGR32249.1 - 2.5e-42 144.4 0.0 6.7e-42 143.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGR32249.1 - 8.5e-13 47.9 0.3 2e-12 46.7 0.3 1.6 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 EGR32249.1 - 2.5e-08 33.7 0.1 1e-07 31.8 0.1 1.9 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 EGR32249.1 - 4.2e-06 27.2 0.0 0.0013 19.1 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EGR32249.1 - 1.1e-05 25.5 0.1 7.4e-05 22.8 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGR32249.1 - 1.2e-05 25.5 0.0 2.5e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGR32249.1 - 0.00014 21.6 0.0 0.00034 20.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EGR32249.1 - 0.00075 20.0 0.1 0.0038 17.8 0.0 2.2 3 0 0 3 3 2 1 AAA domain Prot_ATP_OB_N PF17758.1 EGR32249.1 - 0.001 18.7 0.1 0.0021 17.7 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB N-terminal domain AAA_22 PF13401.6 EGR32249.1 - 0.0017 18.6 0.1 0.021 15.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.13 EGR32249.1 - 0.0035 16.5 0.0 0.0077 15.4 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EGR32249.1 - 0.0036 17.7 0.0 0.008 16.6 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_7 PF12775.7 EGR32249.1 - 0.0045 16.5 0.0 0.012 15.2 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 EGR32249.1 - 0.0079 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 EGR32249.1 - 0.0083 15.9 1.0 0.2 11.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGR32249.1 - 0.0088 15.8 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 EGR32249.1 - 0.0092 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain TIP49 PF06068.13 EGR32249.1 - 0.012 14.8 0.0 0.026 13.7 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 EGR32249.1 - 0.013 15.4 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Spc7 PF08317.11 EGR32249.1 - 0.021 13.7 1.4 0.04 12.8 1.4 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Parvo_NS1 PF01057.17 EGR32249.1 - 0.023 13.8 0.0 0.041 13.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 OmpH PF03938.14 EGR32249.1 - 0.028 14.7 0.9 0.077 13.3 0.9 1.7 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spectrin PF00435.21 EGR32249.1 - 0.03 14.8 1.7 0.42 11.1 2.0 2.4 2 0 0 2 2 2 0 Spectrin repeat AAA_33 PF13671.6 EGR32249.1 - 0.031 14.4 0.2 0.081 13.1 0.0 2.0 2 1 0 2 2 1 0 AAA domain AAA_28 PF13521.6 EGR32249.1 - 0.038 14.2 0.0 0.1 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGR32249.1 - 0.043 13.5 0.1 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EGR32249.1 - 0.059 13.1 0.0 0.17 11.6 0.0 1.8 1 1 1 2 2 2 0 Sigma-54 interaction domain DUF4164 PF13747.6 EGR32249.1 - 0.12 12.7 3.1 0.16 12.3 1.6 2.0 2 0 0 2 2 1 0 Domain of unknown function (DUF4164) Torsin PF06309.11 EGR32249.1 - 0.14 12.3 0.0 0.59 10.2 0.0 1.9 2 0 0 2 2 2 0 Torsin AAA_30 PF13604.6 EGR32249.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain PP2C PF00481.21 EGR32250.1 - 4.5e-47 160.9 0.1 9e-47 159.9 0.1 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGR32250.1 - 0.00022 20.9 0.0 0.00042 20.0 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGR32250.1 - 0.0028 17.6 0.0 0.012 15.5 0.0 2.1 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Sod_Fe_C PF02777.18 EGR32250.1 - 0.049 13.8 0.1 0.049 13.8 0.1 2.2 3 0 0 3 3 3 0 Iron/manganese superoxide dismutases, C-terminal domain GP41 PF00517.17 EGR32250.1 - 4 7.3 16.0 0.7 9.8 1.4 3.3 3 0 0 3 3 3 0 Retroviral envelope protein CoA_trans PF01144.23 EGR32251.1 - 6.4e-96 319.9 0.3 3.4e-61 206.4 0.0 2.1 2 0 0 2 2 2 2 Coenzyme A transferase Mal_decarbox_Al PF16957.5 EGR32251.1 - 0.084 11.2 0.0 0.12 10.7 0.0 1.2 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter SBP_bac_5 PF00496.22 EGR32252.1 - 0.044 12.7 0.1 0.049 12.6 0.1 1.1 1 0 0 1 1 1 0 Bacterial extracellular solute-binding proteins, family 5 Middle TPR_2 PF07719.17 EGR32253.1 - 1.1e-05 25.1 6.9 0.14 12.3 0.1 5.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGR32253.1 - 0.00058 19.6 17.6 0.0042 16.9 0.2 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGR32253.1 - 0.0015 19.0 0.0 0.56 10.8 0.0 3.7 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGR32253.1 - 0.0093 16.2 0.2 5.8 7.3 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGR32253.1 - 0.013 15.6 14.4 0.83 10.0 0.1 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGR32253.1 - 0.13 12.3 1.8 15 5.9 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Phage_Gp23 PF10669.9 EGR32253.1 - 0.25 11.7 5.2 1 9.7 2.2 2.4 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Metallophos PF00149.28 EGR32254.1 - 1.6e-31 110.4 1.1 2.5e-31 109.8 0.2 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Syja_N PF02383.18 EGR32254.1 - 3.6e-06 26.5 2.3 0.03 13.6 0.4 2.6 1 1 1 2 2 2 2 SacI homology domain Penicil_amidase PF01804.18 EGR32255.1 - 1.3e-165 553.2 0.0 1.4e-165 553.0 0.0 1.0 1 0 0 1 1 1 1 Penicillin amidase HSP90 PF00183.18 EGR32257.1 - 9.1e-233 773.8 34.7 1.2e-232 773.4 34.7 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EGR32257.1 - 1.2e-13 51.5 0.1 2.4e-13 50.5 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGR32257.1 - 1.5e-10 41.0 0.1 4.3e-10 39.6 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PaRep2b PF07775.11 EGR32258.1 - 0.0054 15.3 0.8 0.0066 15.0 0.8 1.1 1 0 0 1 1 1 1 PaRep2b protein FHA PF00498.26 EGR32259.1 - 2.9e-15 56.4 0.4 5.2e-15 55.5 0.4 1.4 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGR32259.1 - 3.5e-06 27.2 0.0 5.2e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain DcpS_C PF11969.8 EGR32259.1 - 0.00084 19.8 0.8 0.002 18.6 0.8 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Peptidase_S9 PF00326.21 EGR32260.1 - 1.2e-39 136.1 0.0 1.9e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Band_7 PF01145.25 EGR32261.1 - 8.5e-29 100.8 0.7 1.4e-28 100.1 0.7 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Metallophos PF00149.28 EGR32261.1 - 1.2e-09 39.0 1.8 1.9e-09 38.3 1.8 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 EGR32261.1 - 6.1e-07 29.0 1.5 8.2e-07 28.6 0.1 1.8 2 1 0 2 2 2 1 Metallophosphoesterase, calcineurin superfamily Furin-like_2 PF15913.5 EGR32261.1 - 2.5e-05 24.4 36.7 0.0002 21.5 11.0 13.5 2 2 11 14 14 14 8 Furin-like repeat, cysteine-rich VSP PF03302.13 EGR32261.1 - 0.00015 20.7 32.8 0.00015 20.7 32.8 8.1 2 2 6 8 8 8 5 Giardia variant-specific surface protein Metallophos_2 PF12850.7 EGR32261.1 - 0.00057 20.1 0.0 0.0024 18.1 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TNFR_c6 PF00020.18 EGR32261.1 - 0.0051 17.2 2.1 0.0051 17.2 2.1 16.6 13 6 2 15 15 15 1 TNFR/NGFR cysteine-rich region Band_7_1 PF13421.6 EGR32261.1 - 0.077 12.7 0.1 0.16 11.7 0.1 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family Ribosomal_L31e PF01198.19 EGR32262.1 - 9.1e-37 125.2 2.8 1.2e-36 124.8 2.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e efb-c PF12199.8 EGR32262.1 - 0.087 12.9 1.8 0.12 12.4 1.8 1.3 1 0 0 1 1 1 0 Extracellular fibrinogen binding protein C terminal OmpH PF03938.14 EGR32263.1 - 1.8 8.9 12.2 0.34 11.2 2.8 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Mito_carr PF00153.27 EGR32264.1 - 1.1e-55 185.6 0.3 3.1e-18 65.5 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein MORN PF02493.20 EGR32265.1 - 9.1e-19 66.2 18.9 5.6e-08 32.2 2.7 4.8 5 0 0 5 5 5 4 MORN repeat DUF3048_C PF17479.2 EGR32265.1 - 0.041 14.3 2.0 0.7 10.3 0.1 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3048) C-terminal domain Pkinase_Tyr PF07714.17 EGR32266.1 - 3.3e-46 157.7 0.1 9.2e-42 143.1 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EGR32266.1 - 4.7e-41 140.9 0.4 1.9e-36 125.8 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Haspin_kinase PF12330.8 EGR32266.1 - 2.4e-07 30.1 0.1 0.00012 21.2 0.2 2.2 1 1 1 2 2 2 2 Haspin like kinase domain Pkinase_fungal PF17667.1 EGR32266.1 - 1e-05 24.6 0.1 1.5e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR32266.1 - 0.0067 15.8 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF836 PF05768.14 EGR32266.1 - 0.032 14.6 0.1 0.19 12.2 0.0 2.2 1 1 1 2 2 2 0 Glutaredoxin-like domain (DUF836) Choline_kinase PF01633.20 EGR32266.1 - 0.043 13.4 0.2 0.084 12.4 0.2 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.22 EGR32266.1 - 0.085 12.4 0.4 0.23 11.1 0.1 1.9 2 0 0 2 2 2 0 RIO1 family APH PF01636.23 EGR32266.1 - 0.21 11.5 0.1 0.39 10.6 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family MORN PF02493.20 EGR32267.1 - 4.3e-54 177.3 64.9 2.1e-07 30.4 1.8 10.1 10 0 0 10 10 10 10 MORN repeat CLTH PF10607.9 EGR32268.1 - 1e-12 48.2 7.6 1.7e-12 47.4 7.6 1.3 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EGR32268.1 - 8.5e-07 28.7 0.2 2.2e-06 27.4 0.2 1.7 1 0 0 1 1 1 1 LisH DUF4857 PF16149.5 EGR32268.1 - 0.0011 18.3 0.9 0.002 17.5 0.3 1.6 1 1 1 2 2 2 1 Domain of unknown function (DUF4857) TFIIIC_sub6 PF10419.9 EGR32268.1 - 0.038 13.9 0.0 0.055 13.3 0.0 1.3 1 0 0 1 1 1 0 TFIIIC subunit triple barrel domain MGS PF02142.22 EGR32268.1 - 0.44 10.8 2.2 1.8 8.8 0.6 2.5 1 1 1 2 2 2 0 MGS-like domain HSP70 PF00012.20 EGR32269.1 - 1.8e-244 812.4 17.1 2.1e-244 812.2 17.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGR32269.1 - 4.6e-22 78.3 1.7 1.6e-20 73.2 0.8 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EGR32269.1 - 0.00036 20.9 7.3 0.14 12.6 0.0 3.8 3 1 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 EGR32269.1 - 0.00098 18.9 0.0 0.0025 17.5 0.0 1.7 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 EGR32269.1 - 0.012 14.9 0.4 0.012 14.9 0.4 3.5 4 1 0 4 4 4 0 Hydantoinase/oxoprolinase CPSase_L_D2 PF02786.17 EGR32269.1 - 0.026 14.0 0.2 0.087 12.3 0.0 1.9 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, ATP binding domain CdiI_2 PF18593.1 EGR32269.1 - 0.063 13.9 3.1 3.6 8.3 1.1 3.5 2 1 1 3 3 3 0 CdiI immunity protein GLE1 PF07817.13 EGR32269.1 - 0.18 11.0 0.0 0.18 11.0 0.0 2.2 3 0 0 3 3 3 0 GLE1-like protein Trans_reg_C PF00486.28 EGR32269.1 - 0.18 11.9 0.7 0.83 9.8 0.1 2.3 2 0 0 2 2 2 0 Transcriptional regulatory protein, C terminal TRAF_BIRC3_bd PF16673.5 EGR32269.1 - 0.3 10.9 3.7 9.3 6.1 0.6 3.5 3 0 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain Mod_r PF07200.13 EGR32269.1 - 1.9 8.6 12.9 0.26 11.4 7.1 2.2 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF4795 PF16043.5 EGR32269.1 - 2 8.0 15.8 0.51 9.9 9.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) DUF3289 PF11692.8 EGR32269.1 - 3.2 7.3 7.6 0.48 10.0 2.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3289) MutS_III PF05192.18 EGR32269.1 - 3.2 7.9 8.5 24 5.1 3.4 2.6 2 1 0 2 2 2 0 MutS domain III MPM1 PF17234.2 EGR32270.1 - 1.1 9.5 12.3 1.2 9.4 12.3 1.0 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 DnaJ_C PF01556.18 EGR32271.1 - 7.3e-29 100.8 0.3 1e-28 100.3 0.3 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGR32271.1 - 2.5e-17 62.7 2.1 4.8e-17 61.8 2.1 1.5 1 0 0 1 1 1 1 DnaJ domain Peptidase_M73 PF12389.8 EGR32272.1 - 0.028 14.2 1.5 0.037 13.8 1.5 1.2 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase Stap_Strp_toxin PF01123.20 EGR32272.1 - 0.042 14.7 1.4 0.068 14.0 1.4 1.5 1 0 0 1 1 1 0 Staphylococcal/Streptococcal toxin, OB-fold domain ZapB PF06005.12 EGR32272.1 - 0.05 14.0 17.0 0.071 13.6 0.4 3.2 1 1 2 3 3 3 0 Cell division protein ZapB CENP-F_leu_zip PF10473.9 EGR32272.1 - 0.061 13.3 5.1 0.087 12.8 5.1 1.3 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CCDC92 PF14916.6 EGR32272.1 - 0.3 10.9 5.8 7.4 6.4 0.1 3.5 3 1 1 4 4 4 0 Coiled-coil domain of unknown function GIT_CC PF16559.5 EGR32272.1 - 0.8 9.6 12.1 0.27 11.1 1.4 3.1 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor Serpin PF00079.20 EGR32275.1 - 2.3e-51 175.3 2.9 2.6e-51 175.1 2.9 1.0 1 0 0 1 1 1 1 Serpin (serine protease inhibitor) Arf PF00025.21 EGR32276.1 - 4.5e-54 182.5 0.7 2.2e-44 151.0 0.7 2.0 1 1 1 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EGR32276.1 - 2e-12 47.4 0.1 2.7e-12 47.0 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGR32276.1 - 4.4e-11 42.6 2.4 2.4e-05 23.6 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGR32276.1 - 1.3e-07 31.2 0.0 1.7e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 EGR32276.1 - 2.6e-07 30.4 0.0 3.2e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EGR32276.1 - 2.1e-06 27.8 0.0 2.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGR32276.1 - 3.2e-05 23.4 0.0 4.3e-05 23.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit TniB PF05621.11 EGR32276.1 - 0.0055 16.1 0.1 0.0072 15.8 0.1 1.2 1 0 0 1 1 1 1 Bacterial TniB protein AAA_14 PF13173.6 EGR32276.1 - 0.1 12.6 0.2 0.48 10.5 0.2 2.0 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGR32276.1 - 0.12 12.2 0.3 0.19 11.6 0.2 1.3 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea VbhA PF18495.1 EGR32276.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Antitoxin VbhA Intein_splicing PF14890.6 EGR32277.1 - 1 9.3 2.6 1.5 8.8 2.5 1.4 1 1 0 1 1 1 0 Intein splicing domain Serpin PF00079.20 EGR32278.1 - 2.2e-86 290.5 9.5 2.2e-86 290.5 9.5 1.6 2 0 0 2 2 2 1 Serpin (serine protease inhibitor) LRR_4 PF12799.7 EGR32278.1 - 1.3e-16 60.4 42.5 2.1e-07 31.1 2.1 6.3 6 0 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGR32278.1 - 1.8e-11 43.8 23.9 2e-06 27.4 5.9 4.5 3 1 2 5 5 5 3 Leucine-rich repeat LRR_8 PF13855.6 EGR32278.1 - 3.7e-11 42.6 22.1 4.5e-06 26.3 5.0 4.4 3 1 2 5 5 5 4 Leucine rich repeat DUF3823_C PF18003.1 EGR32278.1 - 0.14 12.9 5.6 0.92 10.3 0.2 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3823_C) DAO PF01266.24 EGR32279.1 - 2.2e-40 139.3 0.0 1.9e-39 136.3 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Mqo PF06039.15 EGR32279.1 - 1.9e-08 33.3 0.0 0.00058 18.5 0.0 2.3 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) NAD_binding_8 PF13450.6 EGR32279.1 - 4.5e-05 23.6 0.0 9.7e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGR32279.1 - 0.00043 19.6 0.0 0.00082 18.7 0.0 1.4 1 0 0 1 1 1 1 Thi4 family K_oxygenase PF13434.6 EGR32279.1 - 0.0015 17.7 0.1 0.0084 15.3 0.0 1.9 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 EGR32279.1 - 0.0032 16.7 0.0 0.075 12.3 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase S8_pro-domain PF16470.5 EGR32279.1 - 0.035 14.9 0.2 0.2 12.4 0.0 2.2 2 0 0 2 2 2 0 Peptidase S8 pro-domain YajC PF02699.15 EGR32279.1 - 0.079 12.8 0.4 0.23 11.4 0.4 1.7 1 0 0 1 1 1 0 Preprotein translocase subunit Trp_halogenase PF04820.14 EGR32279.1 - 0.12 11.2 0.0 0.37 9.6 0.0 1.8 2 0 0 2 2 2 0 Tryptophan halogenase PhoLip_ATPase_C PF16212.5 EGR32280.1 - 1.9e-46 158.8 28.2 1.9e-46 158.8 28.2 3.2 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EGR32280.1 - 4.8e-13 49.9 0.0 3.3e-08 34.1 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGR32280.1 - 1.2e-12 47.7 0.1 1.2e-12 47.7 0.1 2.9 2 1 0 2 2 2 1 E1-E2 ATPase PhoLip_ATPase_N PF16209.5 EGR32280.1 - 9.9e-12 44.4 11.0 9.9e-12 44.4 11.0 3.4 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGR32280.1 - 1.4e-11 44.3 0.2 9.8e-10 38.4 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) TPM_phosphatase PF04536.14 EGR32280.1 - 0.029 14.5 0.2 0.086 13.0 0.2 1.8 1 0 0 1 1 1 0 TPM domain DUF4392 PF14336.6 EGR32280.1 - 0.034 13.6 0.5 0.11 12.0 0.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) Hydrolase_3 PF08282.12 EGR32280.1 - 0.056 13.2 0.0 0.056 13.2 0.0 3.9 3 1 0 4 4 4 0 haloacid dehalogenase-like hydrolase TPR_19 PF14559.6 EGR32281.1 - 1.9e-18 66.7 8.8 1.4e-07 31.9 0.7 3.9 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGR32281.1 - 8.3e-13 47.4 23.2 0.012 15.7 0.3 6.1 6 1 1 7 7 7 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR32281.1 - 1.8e-12 47.3 12.9 1.6e-06 28.2 1.0 3.5 1 1 2 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EGR32281.1 - 8.2e-09 34.9 28.0 0.0052 16.6 1.3 6.4 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGR32281.1 - 1e-08 35.0 6.8 0.018 15.4 0.2 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGR32281.1 - 1e-08 35.3 10.8 0.17 12.2 2.7 5.7 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGR32281.1 - 1.1e-08 34.6 27.8 0.0043 17.1 3.2 6.6 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_6 PF13174.6 EGR32281.1 - 2.1e-07 31.1 18.6 0.072 13.8 0.2 6.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGR32281.1 - 2.6e-06 27.8 0.0 0.26 12.2 0.0 4.8 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGR32281.1 - 5.7e-06 26.9 0.0 0.0067 17.1 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGR32281.1 - 5.8e-06 26.3 12.2 0.012 15.7 3.3 3.4 3 0 0 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 EGR32281.1 - 3.6e-05 23.4 20.1 0.0013 18.4 6.8 5.2 5 1 1 6 6 6 1 TPR repeat TPR_7 PF13176.6 EGR32281.1 - 0.00048 20.0 9.5 15 5.9 0.0 6.1 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 EGR32281.1 - 0.00079 19.7 2.4 0.41 11.0 0.1 3.5 1 1 1 3 3 3 1 Tetratricopeptide repeat ChAPs PF09295.10 EGR32281.1 - 0.0027 16.8 1.5 0.16 11.0 0.1 2.1 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) HrpB1_HrpK PF09613.10 EGR32281.1 - 0.01 15.5 0.1 3.4 7.3 0.0 2.9 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_MalT PF17874.1 EGR32281.1 - 0.02 14.3 1.0 0.83 9.0 0.7 3.0 2 1 0 2 2 2 0 MalT-like TPR region Phage_TAC_13 PF16459.5 EGR32281.1 - 0.021 15.3 1.1 4.1 7.9 0.2 2.3 2 0 0 2 2 2 0 Phage tail assembly chaperone, TAC TPR_9 PF13371.6 EGR32281.1 - 0.023 14.8 0.1 2.3 8.5 0.0 2.9 4 0 0 4 4 2 0 Tetratricopeptide repeat Clathrin PF00637.20 EGR32281.1 - 0.025 14.5 18.9 0.062 13.2 4.8 3.7 1 1 2 3 3 3 0 Region in Clathrin and VPS TPR_10 PF13374.6 EGR32281.1 - 0.028 14.3 7.1 3.8 7.5 0.0 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EGR32281.1 - 0.037 14.1 21.7 0.76 9.8 16.3 3.3 1 1 1 2 2 2 0 Putative TPR-like repeat PPR PF01535.20 EGR32281.1 - 0.06 13.6 0.1 17 5.9 0.0 4.2 4 0 0 4 4 4 0 PPR repeat PPR_2 PF13041.6 EGR32281.1 - 0.18 12.0 0.9 20 5.5 0.0 3.6 4 0 0 4 4 3 0 PPR repeat family HrcA_DNA-bdg PF03444.15 EGR32281.1 - 0.26 11.0 0.2 0.26 11.0 0.2 2.3 3 0 0 3 3 2 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding TBPIP PF07106.13 EGR32283.1 - 9.7e-15 54.3 1.2 9.7e-15 54.3 1.2 2.5 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain Plk4_PB2 PF18409.1 EGR32283.1 - 2.1 9.0 13.3 0.26 12.0 5.2 2.4 2 0 0 2 2 2 0 Polo-like Kinase 4 Polo Box 2 PKcGMP_CC PF16808.5 EGR32284.1 - 0.0068 16.2 37.6 0.49 10.3 2.9 6.4 5 2 1 6 6 6 5 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF1488 PF07369.11 EGR32284.1 - 0.19 11.8 2.7 0.65 10.0 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1488) zf-Sec23_Sec24 PF04810.15 EGR32285.1 - 6.9e-10 38.8 2.2 1.6e-09 37.6 2.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_trunk PF04811.15 EGR32285.1 - 1.8e-08 34.2 2.3 1.7e-07 31.1 0.3 2.8 2 1 0 2 2 2 1 Sec23/Sec24 trunk domain VWA_2 PF13519.6 EGR32285.1 - 3.7e-08 34.0 0.4 0.18 12.5 0.2 3.7 2 1 0 2 2 2 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 EGR32285.1 - 0.0024 17.3 0.0 0.93 8.8 0.0 2.3 2 0 0 2 2 2 2 VWA domain containing CoxE-like protein VWA PF00092.28 EGR32285.1 - 0.03 14.6 6.4 3.7 7.8 0.1 3.5 2 1 1 3 3 3 0 von Willebrand factor type A domain zinc_ribbon_10 PF10058.9 EGR32285.1 - 0.13 12.1 1.6 0.33 10.7 1.6 1.7 1 0 0 1 1 1 0 Predicted integral membrane zinc-ribbon metal-binding protein DUF1323 PF07037.11 EGR32285.1 - 0.67 10.3 4.4 0.46 10.9 0.6 2.6 3 0 0 3 3 3 0 Putative transcription regulator (DUF1323) FERM_M PF00373.18 EGR32285.1 - 0.77 10.2 3.9 11 6.5 0.0 3.2 2 1 0 2 2 2 0 FERM central domain WAC_Acf1_DNA_bd PF10537.9 EGR32285.1 - 1.6 9.3 7.6 8.9 6.9 0.4 3.3 2 1 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal Pkinase PF00069.25 EGR32286.1 - 1.2e-66 224.8 2.2 1.4e-66 224.5 2.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32286.1 - 6.9e-41 140.2 0.2 8.7e-41 139.9 0.2 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR32286.1 - 3.1e-07 30.0 0.0 3.7e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGR32286.1 - 5.7e-06 25.5 1.1 5.7e-06 25.5 1.1 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EGR32286.1 - 0.041 13.2 0.0 0.064 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGR32286.1 - 0.041 13.5 0.4 0.35 10.4 0.1 2.2 1 1 1 2 2 2 0 Choline/ethanolamine kinase APH PF01636.23 EGR32286.1 - 0.17 11.8 0.0 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family DSPc PF00782.20 EGR32287.1 - 9.3e-09 35.2 0.3 3.7e-08 33.2 0.3 1.9 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGR32287.1 - 1.4e-06 28.0 0.1 1.8e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGR32287.1 - 9.7e-05 22.5 0.0 0.00013 22.1 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EGR32287.1 - 0.00012 22.1 0.0 0.00021 21.4 0.0 1.5 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPn PF14671.6 EGR32287.1 - 0.00015 22.2 0.6 0.00035 21.0 0.5 1.7 1 1 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half CDKN3 PF05706.12 EGR32287.1 - 0.0045 16.7 0.1 0.006 16.3 0.1 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase2 PF03162.13 EGR32287.1 - 0.0054 16.3 2.4 0.011 15.3 1.1 2.2 1 1 0 1 1 1 1 Tyrosine phosphatase family AAA_6 PF12774.7 EGR32288.1 - 2.1e-151 503.5 0.2 5.1e-149 495.7 0.0 4.0 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region Dynein_C PF18199.1 EGR32288.1 - 1.9e-109 365.6 0.0 1.9e-109 365.6 0.0 4.2 4 0 0 4 4 3 1 Dynein heavy chain C-terminal domain DHC_N2 PF08393.13 EGR32288.1 - 6.9e-98 328.3 34.2 6.9e-98 328.3 34.2 6.0 4 1 0 5 5 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 EGR32288.1 - 1.5e-83 280.1 3.5 1.5e-83 280.1 3.5 4.9 6 0 0 6 6 6 1 P-loop containing dynein motor region D4 AAA_7 PF12775.7 EGR32288.1 - 1e-66 223.9 0.5 9e-63 211.0 0.0 4.2 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGR32288.1 - 9.9e-58 194.6 0.7 5.1e-57 192.3 0.7 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 EGR32288.1 - 1.5e-39 134.7 0.0 1.5e-38 131.6 0.0 3.0 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 EGR32288.1 - 9.8e-18 64.2 0.1 1.4e-16 60.5 0.1 3.3 1 1 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGR32288.1 - 1.4e-16 60.8 0.0 3.5e-05 23.8 0.0 5.7 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA PF00004.29 EGR32288.1 - 9.7e-09 35.8 2.3 0.0027 18.1 0.0 4.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGR32288.1 - 3.6e-05 24.3 0.4 2.4 8.7 0.0 6.4 5 0 0 5 5 4 1 AAA domain Dynein_AAA_lid PF17852.1 EGR32288.1 - 0.00025 21.1 1.3 0.003 17.6 0.1 3.6 3 0 0 3 3 3 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 EGR32288.1 - 0.0031 17.8 2.2 0.59 10.4 0.0 4.3 4 0 0 4 4 4 1 AAA domain T2SSE PF00437.20 EGR32288.1 - 0.0043 16.1 0.0 0.03 13.4 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_16 PF13191.6 EGR32288.1 - 0.0084 16.5 0.1 69 3.8 0.0 4.6 4 1 1 5 5 4 0 AAA ATPase domain Sigma54_activat PF00158.26 EGR32288.1 - 0.031 14.0 0.1 2.5 7.8 0.0 3.4 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_30 PF13604.6 EGR32288.1 - 0.13 12.0 0.1 5.8 6.6 0.1 2.5 3 0 0 3 3 2 0 AAA domain Spaetzle PF16077.5 EGR32288.1 - 5.2 7.7 18.3 0.017 15.7 4.6 3.7 3 0 0 3 3 2 0 Spaetzle zf-RING_2 PF13639.6 EGR32289.1 - 4.1e-11 43.0 6.7 6.5e-11 42.4 6.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGR32289.1 - 4.8e-06 26.3 8.3 6.7e-06 25.9 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGR32289.1 - 7.6e-06 25.8 7.1 1.2e-05 25.2 7.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 EGR32289.1 - 1.1e-05 25.1 2.1 1.1e-05 25.1 2.1 2.4 3 0 0 3 3 3 1 RING-like zinc finger zf-rbx1 PF12678.7 EGR32289.1 - 1.8e-05 25.0 10.9 7e-05 23.0 10.9 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGR32289.1 - 3.6e-05 23.5 6.3 6.6e-05 22.7 6.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 EGR32289.1 - 5e-05 23.3 7.4 8.6e-05 22.6 7.4 1.4 1 0 0 1 1 1 1 RING-variant domain zf-C3HC4 PF00097.25 EGR32289.1 - 0.00017 21.4 7.8 0.00017 21.4 7.8 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGR32289.1 - 0.00033 20.2 6.4 0.00054 19.5 6.4 1.4 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EGR32289.1 - 0.00037 20.3 5.8 0.00061 19.6 5.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGR32289.1 - 0.0033 17.4 5.4 0.0049 16.9 5.4 1.3 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger YdjO PF14169.6 EGR32289.1 - 0.0038 16.9 4.7 0.053 13.3 0.6 2.3 2 1 0 2 2 2 1 Cold-inducible protein YdjO zf-RING_UBOX PF13445.6 EGR32289.1 - 0.008 16.2 6.7 0.032 14.3 0.7 2.4 3 0 0 3 3 2 1 RING-type zinc-finger Prok-RING_1 PF14446.6 EGR32289.1 - 0.017 15.1 8.5 1.1 9.2 3.4 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING_14 PF17978.1 EGR32289.1 - 0.021 15.3 5.5 0.03 14.7 5.5 1.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-CHY PF05495.12 EGR32289.1 - 0.046 14.2 9.1 0.057 13.9 9.1 1.1 1 0 0 1 1 1 0 CHY zinc finger DUF983 PF06170.12 EGR32289.1 - 0.07 13.5 0.2 0.29 11.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF983) C1_2 PF03107.16 EGR32289.1 - 0.13 12.6 8.4 0.85 10.0 3.9 2.2 2 0 0 2 2 2 0 C1 domain zf-P11 PF03854.14 EGR32289.1 - 0.34 10.6 9.7 0.34 10.6 8.1 1.8 1 1 1 2 2 2 0 P-11 zinc finger Rtf2 PF04641.12 EGR32289.1 - 1.3 8.4 8.7 0.61 9.4 3.2 2.0 1 1 1 2 2 2 0 Rtf2 RING-finger Ldh_1_N PF00056.23 EGR32290.1 - 1e-32 113.2 0.3 1.5e-32 112.6 0.3 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EGR32290.1 - 1.7e-26 93.2 0.0 3.5e-26 92.1 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Pkinase PF00069.25 EGR32291.1 - 1.3e-43 149.3 3.3 1.3e-43 149.3 3.3 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32291.1 - 7.7e-28 97.5 0.4 7.7e-28 97.5 0.4 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR32291.1 - 6e-08 32.0 16.1 7.5e-08 31.7 15.7 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGR32291.1 - 1.2e-05 24.8 1.5 3.6e-05 23.2 0.1 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGR32291.1 - 0.00029 20.5 0.4 0.00029 20.5 0.4 2.8 2 1 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 EGR32291.1 - 0.0008 18.8 2.3 0.0079 15.5 0.1 2.6 1 1 2 3 3 3 1 Kinase-like APH PF01636.23 EGR32291.1 - 0.014 15.4 1.6 0.036 14.0 0.3 2.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family CBP_BcsQ PF06564.12 EGR32291.1 - 0.024 14.1 2.3 1.4 8.3 0.3 2.2 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ RsgA_GTPase PF03193.16 EGR32291.1 - 1.2 9.1 4.0 3 7.7 4.0 1.7 1 1 0 1 1 1 0 RsgA GTPase HSA PF07529.13 EGR32292.1 - 0.0013 19.0 0.2 0.0013 19.0 0.2 2.2 3 0 0 3 3 3 1 HSA MORN PF02493.20 EGR32293.1 - 5.5e-52 170.7 81.6 1.7e-08 33.9 2.8 9.7 10 0 0 10 10 10 9 MORN repeat DUF1828 PF08861.10 EGR32293.1 - 0.021 15.1 2.8 0.022 15.0 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function DUF1828 MEIOC PF15189.6 EGR32293.1 - 0.045 13.4 4.7 0.091 12.4 4.7 1.4 1 0 0 1 1 1 0 Meiosis-specific coiled-coil domain-containing protein MEIOC IBN_N PF03810.19 EGR32294.1 - 2.8e-05 23.9 10.6 0.0001 22.1 2.1 4.2 4 0 0 4 4 4 2 Importin-beta N-terminal domain HATPase_c PF02518.26 EGR32295.1 - 8.3e-20 71.4 0.8 1.3e-19 70.7 0.8 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGR32295.1 - 1e-10 41.4 1.4 3.1e-10 39.9 0.1 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 EGR32295.1 - 0.0038 17.1 0.2 0.012 15.4 0.2 1.9 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase JmjC PF02373.22 EGR32296.1 - 3.5e-33 114.4 9.6 2e-32 112.0 0.4 3.2 3 0 0 3 3 3 2 JmjC domain, hydroxylase JmjN PF02375.17 EGR32296.1 - 3.5e-12 46.1 0.1 8.3e-12 44.9 0.1 1.7 1 0 0 1 1 1 1 jmjN domain Casc1 PF12366.8 EGR32296.1 - 1.8 8.0 9.9 0.17 11.4 5.3 1.6 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 Pkinase PF00069.25 EGR32297.1 - 4.1e-18 65.7 0.0 6.7e-18 65.0 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32297.1 - 3.2e-08 33.2 0.0 4.6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR32297.1 - 0.012 15.0 0.0 0.018 14.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 EGR32298.1 - 1.2e-08 34.7 1.2 2.5e-08 33.6 1.1 1.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32298.1 - 1e-05 24.9 0.5 1.2e-05 24.7 0.5 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 EGR32300.1 - 4.2e-21 74.8 0.0 1e-16 60.8 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain FliH PF02108.16 EGR32301.1 - 0.28 11.3 6.6 0.048 13.7 2.6 1.7 2 0 0 2 2 2 0 Flagellar assembly protein FliH VSP PF03302.13 EGR32302.1 - 1.6e-15 56.9 187.2 4.9e-05 22.4 31.8 7.5 2 1 6 8 8 8 7 Giardia variant-specific surface protein ASC PF00858.24 EGR32303.1 - 0.0034 16.4 1.2 0.0035 16.4 0.1 1.5 2 0 0 2 2 2 1 Amiloride-sensitive sodium channel UAA PF08449.11 EGR32304.1 - 1.8e-43 148.9 24.4 2.2e-43 148.6 24.4 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGR32304.1 - 3.2e-10 40.3 22.6 2.5e-06 27.7 10.4 2.5 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 EGR32304.1 - 0.0046 15.9 4.7 0.0046 15.9 4.7 2.9 1 1 2 3 3 3 2 CRT-like, chloroquine-resistance transporter-like DUF1304 PF06993.12 EGR32304.1 - 0.27 11.2 4.7 0.36 10.8 0.2 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1304) PALP PF00291.25 EGR32305.1 - 3.3e-64 217.1 0.0 4e-64 216.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 EGR32305.1 - 2.8e-14 52.7 0.1 5.5e-14 51.7 0.1 1.5 1 0 0 1 1 1 1 C-terminal regulatory domain of Threonine dehydratase VSP PF03302.13 EGR32306.1 - 3e-15 56.0 222.0 5.8e-05 22.1 34.2 7.5 2 1 6 8 8 8 7 Giardia variant-specific surface protein Peptidase_M8 PF01457.16 EGR32307.1 - 1.7e-11 43.5 2.1 2e-11 43.3 2.1 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 EGR32308.1 - 2.9e-38 131.9 0.0 3.5e-38 131.6 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 EGR32309.1 - 3.7e-13 49.0 0.8 3.7e-07 29.2 0.0 2.4 1 1 1 2 2 2 2 Leishmanolysin Beta_elim_lyase PF01212.21 EGR32310.1 - 1.1e-18 67.5 0.0 1.3e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DNA_primase_lrg PF04104.14 EGR32312.1 - 7.4e-48 163.3 8.7 1.1e-47 162.8 8.7 1.2 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Pro_isomerase PF00160.21 EGR32314.1 - 2.4e-48 164.4 0.2 3.2e-48 164.0 0.2 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4428 PF14471.6 EGR32315.1 - 0.0052 16.7 0.9 0.012 15.5 0.9 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4428) PAN_3 PF08277.12 EGR32315.1 - 0.6 10.0 4.3 11 5.9 0.3 2.4 2 0 0 2 2 2 0 PAN-like domain DUF349 PF03993.12 EGR32315.1 - 0.62 10.4 3.6 9.1 6.7 0.5 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Lectin_N PF03954.14 EGR32316.1 - 0.038 13.7 0.6 0.12 12.2 0.6 1.9 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain Mcl1_mid PF12341.8 EGR32317.1 - 8e-49 166.6 0.0 1.7e-48 165.5 0.0 1.5 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region DIM1 PF02966.16 EGR32318.1 - 5e-69 230.2 0.2 5.7e-69 230.0 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EGR32318.1 - 1.4e-05 25.0 0.0 1.8e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGR32318.1 - 0.017 15.4 0.4 0.028 14.7 0.4 1.5 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.6 EGR32318.1 - 0.033 14.4 0.0 0.057 13.6 0.0 1.5 2 0 0 2 2 2 0 Thioredoxin-like adh_short PF00106.25 EGR32319.1 - 4.8e-36 124.0 0.0 7.2e-35 120.2 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGR32319.1 - 8e-23 81.2 0.0 1.1e-21 77.5 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGR32319.1 - 1e-07 32.0 0.0 1.4e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGR32319.1 - 9.2e-05 22.0 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 2-Hacid_dh_C PF02826.19 EGR32319.1 - 0.032 13.6 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AmpE PF17113.5 EGR32319.1 - 0.039 13.3 0.3 0.3 10.4 0.0 2.0 2 0 0 2 2 2 0 Regulatory signalling modulator protein AmpE Polysacc_synt_2 PF02719.15 EGR32319.1 - 0.059 12.5 0.1 0.43 9.7 0.0 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.8 EGR32319.1 - 0.13 12.0 0.1 0.25 11.1 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Sortilin-Vps10 PF15902.5 EGR32320.1 - 5e-82 276.1 15.7 3e-81 273.5 15.7 2.2 1 1 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EGR32320.1 - 1.9e-41 142.2 2.8 3.6e-41 141.3 2.8 1.5 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR_6 PF15899.5 EGR32320.1 - 0.03 14.4 3.7 0.059 13.5 0.0 3.3 3 0 0 3 3 3 0 BNR-Asp box repeat REPA_OB_2 PF16900.5 EGR32321.1 - 3.4e-17 62.2 1.5 3.4e-17 62.2 1.5 1.9 2 0 0 2 2 2 1 Replication protein A OB domain Rep_fac-A_C PF08646.10 EGR32321.1 - 8.1e-10 38.6 0.1 8.1e-10 38.6 0.1 2.1 2 1 0 2 2 2 1 Replication factor-A C terminal domain DUF3109 PF11307.8 EGR32321.1 - 0.12 12.1 4.1 0.17 11.7 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3109) DiS_P_DiS PF06750.13 EGR32322.1 - 0.035 14.2 0.1 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain PP1_bind PF15276.6 EGR32322.1 - 0.05 13.9 0.0 0.11 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein phosphatase 1 binding Pkinase PF00069.25 EGR32323.1 - 1.8e-62 211.1 1.9 1.8e-62 211.1 1.9 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32323.1 - 1.4e-32 113.0 0.3 1.4e-32 113.0 0.3 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EGR32323.1 - 5.4e-06 25.9 0.1 1.4e-05 24.5 0.1 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR32323.1 - 0.0041 17.1 0.0 1.4 8.8 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 EGR32324.1 - 5.5e-27 94.8 0.1 6.7e-27 94.5 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32324.1 - 9.9e-18 64.4 0.0 1.3e-17 64.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR32324.1 - 3.1e-08 32.8 0.0 4.2e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pox_ser-thr_kin PF05445.11 EGR32324.1 - 0.0048 15.9 0.1 0.0078 15.2 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase Kdo PF06293.14 EGR32324.1 - 0.031 13.6 0.0 0.048 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR32324.1 - 0.066 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ribosomal_S9 PF00380.19 EGR32325.1 - 1.1e-33 116.4 0.1 4.2e-33 114.4 0.0 2.1 2 0 0 2 2 2 1 Ribosomal protein S9/S16 Pkinase PF00069.25 EGR32326.1 - 2.4e-29 102.5 0.0 9e-27 94.1 0.0 2.6 1 1 0 1 1 1 1 Protein kinase domain EF-hand_7 PF13499.6 EGR32326.1 - 6.2e-29 100.3 18.3 1.4e-11 44.7 1.8 4.2 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 EGR32326.1 - 1.8e-25 86.5 27.3 3e-07 29.5 1.1 6.9 7 0 0 7 7 6 5 EF hand EF-hand_6 PF13405.6 EGR32326.1 - 5.6e-24 82.0 22.2 6.6e-06 25.7 1.0 6.1 5 0 0 5 5 5 5 EF-hand domain Pkinase_Tyr PF07714.17 EGR32326.1 - 7.1e-18 64.8 0.0 1.5e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_8 PF13833.6 EGR32326.1 - 1.7e-16 59.8 23.9 2.1e-05 24.3 1.5 6.0 4 2 2 6 6 6 4 EF-hand domain pair EF-hand_5 PF13202.6 EGR32326.1 - 1.9e-15 55.5 22.5 7.4e-06 25.2 1.2 5.9 6 0 0 6 6 6 4 EF hand SPARC_Ca_bdg PF10591.9 EGR32326.1 - 5e-09 36.5 8.3 0.0017 18.7 0.2 3.3 3 0 0 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGR32326.1 - 2.9e-07 30.4 18.0 0.028 14.4 1.0 4.6 1 1 3 5 5 5 3 Cytoskeletal-regulatory complex EF hand RST PF12174.8 EGR32326.1 - 6.1e-07 29.3 1.1 0.08 12.9 0.0 3.6 3 0 0 3 3 3 3 RCD1-SRO-TAF4 (RST) plant domain Pkinase_fungal PF17667.1 EGR32326.1 - 8.6e-05 21.5 0.0 0.00016 20.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase p25-alpha PF05517.12 EGR32326.1 - 0.00015 22.0 15.8 0.17 12.1 1.5 4.2 2 1 2 4 4 4 2 p25-alpha EF-hand_11 PF08976.11 EGR32326.1 - 0.0018 19.1 4.1 0.0053 17.6 0.1 3.0 2 2 1 3 3 3 1 EF-hand domain bacHORMA_2 PF18173.1 EGR32326.1 - 0.13 12.1 0.1 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial HORMA domain 2 EF-hand_14 PF17959.1 EGR32326.1 - 0.91 9.9 8.0 8.7 6.8 1.7 3.0 1 1 1 2 2 2 0 EF-hand domain Dockerin_1 PF00404.18 EGR32326.1 - 1.4 9.2 13.8 1 9.6 0.2 4.1 3 2 1 4 4 4 0 Dockerin type I domain Haemagg_act PF05860.13 EGR32326.1 - 1.5 8.7 11.5 5.2 7.0 1.1 3.2 2 1 1 3 3 3 0 haemagglutination activity domain EF-hand_10 PF14788.6 EGR32326.1 - 2.4 8.1 9.1 19 5.2 0.3 4.1 3 1 1 4 4 4 0 EF hand EF-hand_1 PF00036.32 EGR32327.1 - 1.5e-13 49.2 14.4 0.001 18.5 0.3 5.2 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 EGR32327.1 - 2.3e-13 50.4 7.5 1.1e-05 25.8 0.1 3.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EGR32327.1 - 2.3e-12 45.8 15.5 0.00059 19.6 0.0 5.4 7 0 0 7 7 7 3 EF-hand domain EF-hand_8 PF13833.6 EGR32327.1 - 0.00054 19.8 10.9 0.26 11.2 0.2 3.8 4 0 0 4 4 4 3 EF-hand domain pair YppF PF14178.6 EGR32327.1 - 0.018 14.9 0.1 11 6.0 0.0 3.6 3 0 0 3 3 3 0 YppF-like protein EF-hand_9 PF14658.6 EGR32327.1 - 0.019 15.3 0.0 0.96 9.8 0.0 3.2 2 1 1 3 3 3 0 EF-hand domain PRiA4_ORF3 PF07929.11 EGR32327.1 - 0.084 12.6 0.6 0.18 11.5 0.6 1.5 1 0 0 1 1 1 0 Plasmid pRiA4b ORF-3-like protein EF-hand_14 PF17959.1 EGR32327.1 - 0.13 12.6 9.4 24 5.4 0.9 4.5 3 1 0 3 3 3 0 EF-hand domain EF-hand_5 PF13202.6 EGR32327.1 - 0.18 11.3 8.2 1.5 8.4 0.5 4.2 4 0 0 4 4 4 0 EF hand SPARC_Ca_bdg PF10591.9 EGR32327.1 - 0.4 11.0 5.4 11 6.4 0.3 3.3 1 1 2 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EGR32327.1 - 3.4 8.6 5.2 9.9 7.1 0.1 3.0 2 1 1 3 3 3 0 EF-hand domain HU-CCDC81_euk_1 PF14908.6 EGR32328.1 - 1.5e-19 69.9 0.0 1.5e-19 69.9 0.0 3.2 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 EGR32328.1 - 1.2e-06 28.6 1.3 2.1e-05 24.6 1.3 2.6 1 1 0 1 1 1 1 CCDC81 eukaryotic HU domain 2 EF-hand_1 PF00036.32 EGR32328.1 - 7.6e-05 22.0 8.0 0.13 11.8 0.1 5.3 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 EGR32328.1 - 0.00024 20.8 15.0 0.24 11.4 0.3 6.1 6 0 0 6 6 6 2 EF-hand domain EF-hand_8 PF13833.6 EGR32328.1 - 0.00069 19.4 7.0 0.35 10.8 0.3 4.9 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_7 PF13499.6 EGR32328.1 - 0.0058 17.1 20.2 0.44 11.0 0.4 5.2 4 2 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EGR32328.1 - 0.044 13.3 7.6 0.05 13.1 0.2 4.0 4 0 0 4 4 4 0 EF hand EF-hand_10 PF14788.6 EGR32328.1 - 0.065 13.1 3.1 8.4 6.3 0.0 3.8 3 0 0 3 3 3 0 EF hand TSKS PF15358.6 EGR32328.1 - 0.11 10.9 7.6 0.22 9.8 7.6 1.4 1 0 0 1 1 1 0 Testis-specific serine kinase substrate AAA_6 PF12774.7 EGR32330.1 - 1.9e-156 520.1 2.0 1.3e-154 514.0 0.2 3.6 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGR32330.1 - 4.2e-114 381.7 26.2 4.2e-114 381.7 26.2 6.1 6 0 0 6 6 4 1 Dynein heavy chain, N-terminal region 2 Dynein_C PF18199.1 EGR32330.1 - 9e-108 360.1 0.2 9e-108 360.1 0.2 4.0 4 0 0 4 4 4 1 Dynein heavy chain C-terminal domain AAA_8 PF12780.7 EGR32330.1 - 7e-83 277.9 2.3 7e-83 277.9 2.3 5.2 4 0 0 4 4 3 1 P-loop containing dynein motor region D4 AAA_9 PF12781.7 EGR32330.1 - 2.3e-80 268.9 8.9 2.3e-80 268.9 8.9 5.2 4 1 0 4 4 3 1 ATP-binding dynein motor region AAA_7 PF12775.7 EGR32330.1 - 4e-68 228.5 12.1 5.9e-68 227.9 0.0 5.0 7 0 0 7 7 7 1 P-loop containing dynein motor region AAA_lid_11 PF18198.1 EGR32330.1 - 3e-59 199.5 1.5 2.9e-58 196.3 1.1 3.1 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain MT PF12777.7 EGR32330.1 - 4.8e-48 164.0 8.0 2.1e-47 161.8 8.2 2.1 2 0 0 2 2 2 1 Microtubule-binding stalk of dynein motor Dynein_heavy PF03028.15 EGR32330.1 - 5.2e-46 155.6 0.6 3e-44 149.9 0.2 3.7 2 0 0 2 2 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EGR32330.1 - 2e-27 95.9 0.4 1.9e-26 92.7 0.1 3.1 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EGR32330.1 - 3.8e-14 52.8 0.0 0.0026 17.8 0.0 6.0 4 1 0 4 4 4 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 EGR32330.1 - 4.1e-14 52.6 0.6 4.1e-14 52.6 0.6 4.0 5 0 0 5 5 2 1 AAA+ lid domain AAA_22 PF13401.6 EGR32330.1 - 3.5e-09 37.0 3.2 0.14 12.4 0.0 6.6 6 0 0 6 6 5 2 AAA domain AAA PF00004.29 EGR32330.1 - 5.8e-08 33.2 0.0 0.26 11.7 0.0 5.7 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGR32330.1 - 6.3e-06 26.7 1.9 0.83 10.0 0.0 6.5 7 0 0 7 7 6 1 AAA ATPase domain AAA_18 PF13238.6 EGR32330.1 - 4.3e-05 24.0 1.8 0.44 11.1 0.0 6.6 5 0 0 5 5 5 1 AAA domain AAA_33 PF13671.6 EGR32330.1 - 0.0038 17.4 0.0 8.4 6.5 0.0 4.1 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EGR32330.1 - 0.0069 16.8 2.3 8.3 6.9 0.0 5.3 4 0 0 4 4 3 1 RNA helicase T2SSE PF00437.20 EGR32330.1 - 0.0082 15.2 0.6 0.082 12.0 0.2 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_30 PF13604.6 EGR32330.1 - 0.031 14.0 0.0 3.2 7.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain PAH PF02671.21 EGR32330.1 - 0.12 12.5 0.8 1.8 8.8 0.2 3.5 2 0 0 2 2 2 0 Paired amphipathic helix repeat Thioredoxin PF00085.20 EGR32331.1 - 4.7e-46 155.0 3.3 4.7e-23 81.1 0.1 3.3 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_7 PF13899.6 EGR32331.1 - 6.9e-05 23.0 0.0 0.54 10.5 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EGR32331.1 - 8.6e-05 23.0 10.5 0.00077 19.9 0.1 4.8 4 1 0 4 4 4 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGR32331.1 - 4.5 7.7 20.4 2 8.8 0.0 6.1 5 2 1 6 6 6 0 Thioredoxin-like AhpC-TSA PF00578.21 EGR32331.1 - 8.1 6.4 11.6 0.69 9.8 0.2 3.8 3 1 2 5 5 5 0 AhpC/TSA family DUF1752 PF08550.10 EGR32335.1 - 0.0063 16.3 1.5 1.8 8.5 0.1 3.0 3 0 0 3 3 3 2 Fungal protein of unknown function (DUF1752) Methyltransf_15 PF09445.10 EGR32335.1 - 0.17 11.5 22.4 0.54 9.8 0.8 5.3 1 1 5 6 6 6 0 RNA cap guanine-N2 methyltransferase HU-CCDC81_euk_1 PF14908.6 EGR32336.1 - 8.8e-25 86.7 0.1 1.6e-24 85.8 0.1 1.5 1 0 0 1 1 1 1 CCDC81 eukaryotic HU domain 1 HU-CCDC81_euk_2 PF18289.1 EGR32336.1 - 3.5e-14 52.7 5.1 3.9e-13 49.4 2.1 2.4 1 1 1 2 2 2 1 CCDC81 eukaryotic HU domain 2 Bac_DNA_binding PF00216.21 EGR32336.1 - 0.034 14.4 1.2 12 6.2 0.0 3.5 4 0 0 4 4 4 0 Bacterial DNA-binding protein GP17 PF17420.2 EGR32336.1 - 0.039 14.1 0.6 0.1 12.8 0.3 1.9 1 1 0 1 1 1 0 Superinfection exclusion gene product 17 cNMP_binding PF00027.29 EGR32337.1 - 1.9e-25 88.7 0.4 2.4e-14 53.1 0.0 2.9 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain Ribonuclease_T2 PF00445.18 EGR32337.1 - 0.0053 17.0 1.5 0.012 15.8 1.5 1.7 1 0 0 1 1 1 1 Ribonuclease T2 family ProRS-C_2 PF09181.10 EGR32337.1 - 0.85 9.8 4.0 2 8.6 0.3 2.6 2 0 0 2 2 2 0 Prolyl-tRNA synthetase, C-terminal Peptidase_M8 PF01457.16 EGR32338.1 - 2.8e-06 26.3 0.0 3.6e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 EGR32339.1 - 2.3e-08 33.2 10.5 9.8e-07 27.8 0.8 2.1 1 1 1 2 2 2 2 Leishmanolysin Ras PF00071.22 EGR32340.1 - 2.9e-16 59.5 0.3 3.2e-16 59.4 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR32340.1 - 1.8e-11 44.3 0.1 2.1e-11 44.1 0.1 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR32340.1 - 0.00013 21.5 0.2 0.00014 21.4 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Thioredoxin_15 PF18403.1 EGR32340.1 - 0.086 12.8 0.0 0.086 12.7 0.0 1.0 1 0 0 1 1 1 0 Thioredoxin-like domain adh_short PF00106.25 EGR32342.1 - 1.3e-37 129.2 0.0 1.4e-37 129.0 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGR32342.1 - 7.2e-22 78.1 0.0 8.3e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGR32342.1 - 3.5e-09 36.8 0.0 4.7e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Kinesin PF00225.23 EGR32343.1 - 1e-98 330.3 6.2 1e-98 330.3 6.2 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGR32343.1 - 7.1e-27 94.2 1.8 7.1e-27 94.2 1.8 2.8 3 1 0 3 3 3 1 Microtubule binding Latarcin PF10279.9 EGR32343.1 - 0.0051 17.2 0.0 0.068 13.6 0.0 2.8 1 1 0 1 1 1 1 Latarcin precursor ArgoMid PF16487.5 EGR32343.1 - 0.26 11.5 3.7 17 5.8 1.7 2.9 2 0 0 2 2 2 0 Mid domain of argonaute Methyltrn_RNA_3 PF02598.17 EGR32344.1 - 1e-64 218.8 0.1 1.8e-64 218.0 0.1 1.4 1 0 0 1 1 1 1 Putative RNA methyltransferase EPL1 PF10513.9 EGR32344.1 - 1.3 9.4 12.9 2 8.8 12.0 1.7 1 1 0 1 1 1 0 Enhancer of polycomb-like Ribosomal_S17e PF00833.18 EGR32345.1 - 7.6e-58 193.7 1.0 8.5e-58 193.6 1.0 1.0 1 0 0 1 1 1 1 Ribosomal S17 VSP PF03302.13 EGR32347.1 - 1.4e-15 57.1 217.6 0.00037 19.5 42.2 8.9 2 1 7 9 9 9 8 Giardia variant-specific surface protein Peptidase_M16 PF00675.20 EGR32348.1 - 1.3e-28 99.9 0.0 2.2e-28 99.1 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF3169 PF11368.8 EGR32348.1 - 0.009 15.6 2.5 0.014 14.9 2.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) Peptidase_M16_C PF05193.21 EGR32348.1 - 0.014 15.4 2.0 0.086 12.8 0.3 2.3 2 0 0 2 2 2 0 Peptidase M16 inactive domain PhoLip_ATPase_C PF16212.5 EGR32349.1 - 9.3e-53 179.5 21.3 9.3e-53 179.5 21.3 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EGR32349.1 - 1.4e-11 45.1 1.9 0.0014 19.0 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGR32349.1 - 4.7e-10 39.4 0.8 1e-08 35.2 0.0 3.0 3 0 0 3 3 3 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGR32349.1 - 6e-10 38.9 0.7 4.1e-09 36.2 0.6 2.2 1 1 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGR32349.1 - 0.0057 16.4 3.2 0.0057 16.4 3.2 3.7 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase DUF2183 PF09949.9 EGR32349.1 - 0.052 13.9 1.7 2.1 8.7 0.0 3.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2183) PIP5K PF01504.18 EGR32350.1 - 1.1e-49 169.1 20.0 1.1e-49 169.1 20.0 2.5 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase ICAM_N PF03921.14 EGR32350.1 - 0.17 11.6 0.5 29 4.4 0.0 2.7 2 0 0 2 2 2 0 Intercellular adhesion molecule (ICAM), N-terminal domain Hydrolase_4 PF12146.8 EGR32351.1 - 2.9e-14 52.9 0.0 5.9e-10 38.8 0.0 2.2 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR32351.1 - 3.4e-12 46.5 0.4 1.4e-07 31.5 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EGR32351.1 - 4.6e-08 33.0 0.2 9.6e-05 22.1 0.1 2.5 1 1 1 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EGR32351.1 - 7.2e-06 25.6 1.1 2.3e-05 24.0 0.0 2.3 2 1 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 EGR32351.1 - 9.1e-06 25.4 1.1 0.00077 19.1 0.0 2.6 2 1 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.11 EGR32351.1 - 9.5e-05 22.4 0.1 9.5e-05 22.4 0.1 2.7 3 0 0 3 3 3 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 EGR32351.1 - 0.0014 19.3 0.0 0.0016 19.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 EGR32351.1 - 0.0024 17.5 0.0 0.0051 16.5 0.0 1.6 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 EGR32351.1 - 0.0048 16.7 0.1 0.27 11.0 0.0 3.0 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 EGR32351.1 - 0.0097 15.7 0.1 0.038 13.8 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family FSH1 PF03959.13 EGR32351.1 - 0.018 14.7 0.1 0.018 14.7 0.1 2.0 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Complex1_51K PF01512.17 EGR32352.1 - 0.17 11.8 4.2 0.77 9.6 0.4 2.1 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit Endonuc-BsobI PF09194.10 EGR32354.1 - 0.0026 17.0 0.3 0.0031 16.8 0.3 1.1 1 0 0 1 1 1 1 Restriction endonuclease BsobI MRP-S33 PF08293.11 EGR32354.1 - 0.02 15.1 0.1 0.035 14.3 0.1 1.6 1 1 0 1 1 1 0 Mitochondrial ribosomal subunit S27 Pkinase PF00069.25 EGR32355.1 - 7.7e-61 205.8 0.4 7.7e-61 205.8 0.4 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32355.1 - 1.4e-36 126.1 0.1 2.1e-36 125.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR32355.1 - 1.3e-06 28.0 0.1 6.6e-05 22.4 0.0 2.5 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR32355.1 - 3.3e-06 26.1 1.9 0.00024 20.0 0.0 2.0 2 0 0 2 2 2 2 Fungal protein kinase FTA2 PF13095.6 EGR32355.1 - 0.024 14.3 0.0 0.024 14.3 0.0 1.9 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGR32355.1 - 0.12 12.2 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Vfa1 PF08432.10 EGR32355.1 - 0.55 10.6 13.2 0.83 10.0 13.2 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Ras PF00071.22 EGR32356.1 - 6.3e-56 188.4 0.1 6.3e-56 188.4 0.1 1.8 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EGR32356.1 - 5.2e-36 123.5 0.0 5.2e-36 123.5 0.0 2.5 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR32356.1 - 6.3e-17 61.6 0.3 6.3e-17 61.6 0.3 1.5 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGR32356.1 - 1.7e-05 24.5 2.4 0.00018 21.1 2.3 2.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGR32356.1 - 6.4e-05 23.0 0.1 0.00016 21.8 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGR32356.1 - 0.00076 18.9 6.2 0.0024 17.3 6.2 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGR32356.1 - 0.003 17.0 0.0 0.003 17.0 0.0 2.0 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit DDHD PF02862.17 EGR32356.1 - 2.3 8.3 8.1 3.3 7.8 8.1 1.3 1 0 0 1 1 1 0 DDHD domain O-antigen_lig PF13425.6 EGR32356.1 - 3 6.5 10.4 4.5 5.9 10.4 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Sod_Cu PF00080.20 EGR32357.1 - 3.8e-46 156.8 7.3 4.3e-46 156.6 7.3 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.12 EGR32357.1 - 0.13 13.2 2.7 0.13 13.2 2.1 1.4 1 1 0 1 1 1 0 CHRD domain Pkinase PF00069.25 EGR32358.1 - 7.3e-19 68.1 0.1 8.4e-19 68.0 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGR32358.1 - 1.3e-09 37.3 0.1 1.4e-09 37.3 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 EGR32358.1 - 3.2e-09 36.4 0.0 3.3e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR32358.1 - 0.092 12.7 0.0 0.18 11.7 0.0 1.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGR32358.1 - 0.16 11.3 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EGR32359.1 - 8.3e-80 267.9 0.3 8.3e-80 267.9 0.3 2.5 3 0 0 3 3 3 1 Protein kinase domain UQ_con PF00179.26 EGR32359.1 - 1.5e-38 131.6 0.1 7e-38 129.4 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme Pkinase_Tyr PF07714.17 EGR32359.1 - 2.1e-38 132.1 0.0 4.5e-38 131.0 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EGR32359.1 - 4.9e-15 55.7 11.5 7.4e-10 39.1 0.9 4.2 4 0 0 4 4 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR32359.1 - 3.7e-14 51.1 18.0 1.7e-05 24.0 0.2 6.3 6 0 0 6 6 6 3 EF hand EF-hand_5 PF13202.6 EGR32359.1 - 3.3e-13 48.5 16.2 6.7e-05 22.2 0.0 5.1 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 EGR32359.1 - 1.1e-12 46.7 16.6 9.4e-06 25.2 0.1 5.7 6 0 0 6 6 6 3 EF-hand domain PHM7_cyt PF14703.6 EGR32359.1 - 2.9e-12 47.2 6.4 2.9e-12 47.2 6.4 4.0 4 1 0 4 4 4 1 Cytosolic domain of 10TM putative phosphate transporter EF-hand_8 PF13833.6 EGR32359.1 - 5.7e-09 35.7 8.9 0.089 12.7 0.2 5.4 3 1 2 5 5 5 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGR32359.1 - 4.7e-08 33.3 9.1 8.3e-05 22.9 0.4 4.2 3 1 1 4 4 4 2 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.14 EGR32359.1 - 0.00012 21.5 0.1 0.00026 20.4 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGR32359.1 - 0.00016 21.1 4.8 0.00016 21.1 0.0 3.3 3 0 0 3 3 3 1 Kinase-like Pkinase_fungal PF17667.1 EGR32359.1 - 0.015 14.1 0.0 0.027 13.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase tRNA_synt_1c_R1 PF04558.15 EGR32359.1 - 0.015 15.3 1.3 0.072 13.1 0.1 2.6 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 APH PF01636.23 EGR32359.1 - 0.016 15.2 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Zip PF02535.22 EGR32359.1 - 0.03 13.6 0.3 0.55 9.4 0.1 2.5 2 0 0 2 2 2 0 ZIP Zinc transporter SDH_beta PF03315.15 EGR32359.1 - 0.17 12.2 0.6 1.2 9.5 0.1 2.4 2 0 0 2 2 2 0 Serine dehydratase beta chain DUF5345 PF17280.2 EGR32359.1 - 0.21 11.6 3.7 6.2 6.9 0.1 4.1 4 0 0 4 4 4 0 Family of unknown function (DUF5345) Kelch_4 PF13418.6 EGR32360.1 - 7.8e-15 54.6 0.1 4.3e-07 29.8 0.0 3.4 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EGR32360.1 - 7.3e-12 45.0 0.6 0.00017 21.5 0.0 3.4 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.6 EGR32360.1 - 9.3e-10 38.6 0.5 0.0042 17.3 0.0 3.6 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EGR32360.1 - 1.2e-08 34.9 0.6 0.00056 20.1 0.1 3.2 3 0 0 3 3 3 2 Kelch motif Kelch_1 PF01344.25 EGR32360.1 - 6.7e-08 32.0 0.2 0.096 12.3 0.1 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_2 PF07646.15 EGR32360.1 - 0.0017 18.3 0.3 1.2 9.3 0.0 3.5 3 0 0 3 3 3 1 Kelch motif DUF4763 PF15960.5 EGR32360.1 - 0.067 12.5 2.4 0.1 11.9 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) SpoIIE PF07228.12 EGR32361.1 - 0.057 13.3 0.1 0.47 10.3 0.1 2.2 1 1 0 1 1 1 0 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EGR32361.1 - 0.097 12.3 0.1 0.21 11.2 0.0 1.5 2 0 0 2 2 2 0 Protein phosphatase 2C HARE-HTH PF05066.13 EGR32361.1 - 0.13 12.7 0.0 0.25 11.7 0.0 1.5 1 0 0 1 1 1 0 HB1, ASXL, restriction endonuclease HTH domain VWA PF00092.28 EGR32362.1 - 8.5e-12 45.7 2.1 9.8e-10 39.0 0.0 2.9 3 1 1 4 4 4 2 von Willebrand factor type A domain VWA_2 PF13519.6 EGR32362.1 - 5.6e-07 30.2 0.1 0.00017 22.2 0.0 2.6 1 1 1 2 2 2 2 von Willebrand factor type A domain VWA_3 PF13768.6 EGR32362.1 - 5.1e-06 26.5 0.0 9.9e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EGR32362.1 - 0.012 15.0 0.0 1.8 7.9 0.0 2.1 1 1 1 2 2 2 0 VWA domain containing CoxE-like protein AfaD PF05775.12 EGR32362.1 - 0.087 13.3 0.0 0.16 12.4 0.0 1.4 1 0 0 1 1 1 0 Enterobacteria AfaD invasin protein ThiF PF00899.21 EGR32363.1 - 6.2e-48 163.3 0.2 8.6e-48 162.8 0.2 1.1 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EGR32363.1 - 0.0024 18.1 0.5 0.014 15.6 0.0 2.4 3 0 0 3 3 3 1 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 EGR32363.1 - 0.004 16.5 0.7 0.007 15.7 0.7 1.3 1 0 0 1 1 1 1 FAD binding domain 2-Hacid_dh_C PF02826.19 EGR32363.1 - 0.0096 15.3 0.4 0.026 13.9 0.4 1.6 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EGR32363.1 - 0.018 15.1 0.1 0.042 13.9 0.1 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PglD_N PF17836.1 EGR32363.1 - 0.027 15.1 0.5 0.069 13.8 0.0 2.0 2 1 0 2 2 2 0 PglD N-terminal domain TrkA_N PF02254.18 EGR32363.1 - 0.032 14.5 0.2 0.21 11.9 0.1 2.2 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_7 PF13241.6 EGR32363.1 - 0.036 14.5 0.0 0.091 13.2 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 EGR32363.1 - 0.055 13.1 0.2 0.12 12.0 0.2 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 EGR32363.1 - 0.056 13.0 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Jag_N PF14804.6 EGR32363.1 - 0.36 11.2 2.2 1.3 9.5 2.2 1.9 1 0 0 1 1 1 0 Jag N-terminus PI3_PI4_kinase PF00454.27 EGR32366.1 - 2.9e-24 86.3 1.2 2.9e-24 86.3 1.2 4.1 4 2 0 4 4 4 1 Phosphatidylinositol 3- and 4-kinase NPCC PF08058.11 EGR32366.1 - 0.0024 17.9 1.1 0.0024 17.9 1.1 3.0 2 0 0 2 2 2 1 Nuclear pore complex component Thioredoxin PF00085.20 EGR32367.1 - 7.8e-22 77.2 0.2 1.2e-21 76.6 0.2 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGR32367.1 - 0.00033 21.1 0.3 0.0011 19.4 0.2 1.9 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EGR32367.1 - 0.0015 18.3 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGR32367.1 - 0.011 16.0 0.2 1.6 9.1 0.0 2.8 1 1 2 3 3 3 0 Thioredoxin-like OST3_OST6 PF04756.13 EGR32367.1 - 0.018 14.4 1.1 0.026 13.9 0.8 1.6 1 1 0 1 1 1 0 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EGR32367.1 - 0.048 13.6 0.1 0.073 13.0 0.1 1.4 1 0 0 1 1 1 0 AhpC/TSA family TraF PF13728.6 EGR32367.1 - 0.26 11.1 0.1 0.26 11.1 0.1 1.9 2 0 0 2 2 2 0 F plasmid transfer operon protein MFS_1 PF07690.16 EGR32368.1 - 8.5e-16 57.8 28.5 8.5e-16 57.8 28.5 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily UNC-93 PF05978.16 EGR32368.1 - 1.3e-05 25.0 1.4 1.3e-05 25.0 1.4 4.1 3 2 2 5 5 5 2 Ion channel regulatory protein UNC-93 Pyridoxal_deC PF00282.19 EGR32369.1 - 2.6e-52 177.8 0.0 3.5e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_1_2 PF00155.21 EGR32369.1 - 0.021 14.0 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Pterin_bind PF00809.22 EGR32369.1 - 0.05 13.3 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Pterin binding enzyme Csa1 PF06023.12 EGR32369.1 - 0.26 10.6 1.0 0.42 9.9 1.0 1.2 1 0 0 1 1 1 0 CRISPR-associated exonuclease Csa1 Cullin_Nedd8 PF10557.9 EGR32369.1 - 0.69 10.0 5.0 0.35 11.0 0.6 2.6 2 0 0 2 2 2 0 Cullin protein neddylation domain 2OG-FeII_Oxy_2 PF13532.6 EGR32370.1 - 3.6e-33 115.4 0.0 1.2e-32 113.7 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Thioredoxin_6 PF13848.6 EGR32371.1 - 5.4e-05 23.2 1.0 0.00012 22.0 1.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain Herpes_U26 PF07402.11 EGR32371.1 - 0.035 13.7 3.8 0.064 12.8 3.8 1.4 1 0 0 1 1 1 0 Human herpesvirus U26 protein HSF_DNA-bind PF00447.17 EGR32372.1 - 1.4e-29 102.6 1.7 1.4e-29 102.6 1.7 1.7 2 0 0 2 2 2 1 HSF-type DNA-binding Cwf_Cwc_15 PF04889.12 EGR32372.1 - 0.00023 21.0 20.8 0.00026 20.8 20.8 1.1 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Ets PF00178.22 EGR32372.1 - 0.0068 16.8 1.4 0.019 15.4 0.2 2.1 1 1 1 2 2 2 1 Ets-domain CNDH2_C PF16858.5 EGR32372.1 - 0.01 15.7 11.7 0.01 15.8 11.7 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term DUF4746 PF15928.5 EGR32372.1 - 0.03 13.7 7.2 0.034 13.6 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SDA1 PF05285.12 EGR32372.1 - 0.042 13.3 16.4 0.051 13.0 16.4 1.2 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 EGR32372.1 - 0.16 10.7 10.0 0.19 10.5 10.0 1.1 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 EGR32372.1 - 0.24 11.4 9.3 0.32 10.9 9.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF2457 PF10446.9 EGR32372.1 - 0.9 8.6 26.9 1.2 8.2 26.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SID-1_RNA_chan PF13965.6 EGR32372.1 - 1.2 7.4 3.6 1.3 7.4 3.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Dicty_REP PF05086.12 EGR32372.1 - 1.9 6.4 21.0 2.9 5.8 21.0 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Neur_chan_memb PF02932.16 EGR32372.1 - 2.1 8.4 3.5 2.7 8.0 3.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CSRNP_N PF16019.5 EGR32372.1 - 3.1 7.7 9.8 4.2 7.2 9.8 1.4 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Nop14 PF04147.12 EGR32372.1 - 9 4.4 22.7 9.8 4.2 22.7 1.1 1 0 0 1 1 1 0 Nop14-like family Ion_trans PF00520.31 EGR32373.1 - 1.2e-15 57.5 29.9 2.1e-15 56.6 29.9 1.4 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EGR32373.1 - 6.8e-15 54.9 0.0 1.1e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGR32373.1 - 5.7e-13 48.6 4.0 5.7e-13 48.6 4.0 3.0 3 1 0 3 3 3 1 Ion channel zf-CCHC PF00098.23 EGR32373.1 - 0.00029 20.8 0.9 0.00044 20.2 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle Vac_Fusion PF02346.16 EGR32373.1 - 0.011 15.4 2.1 0.058 13.0 0.3 2.9 2 0 0 2 2 2 0 Chordopoxvirus multifunctional envelope protein A27 DPM3 PF08285.11 EGR32373.1 - 0.97 9.7 5.1 1.3 9.3 0.0 3.2 3 0 0 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) FAD-oxidase_C PF02913.19 EGR32374.1 - 1e-39 136.7 0.0 1.4e-39 136.2 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGR32374.1 - 1.9e-29 102.2 0.0 3.5e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Antimicrobial_3 PF08025.11 EGR32374.1 - 0.1 12.6 0.0 0.27 11.2 0.0 1.7 1 0 0 1 1 1 0 Spider antimicrobial peptide CHASE3 PF05227.13 EGR32374.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 CHASE3 domain Arm-DNA-bind_2 PF12167.8 EGR32376.1 - 0.024 14.5 1.2 0.024 14.5 1.2 2.0 2 0 0 2 2 2 0 Arm DNA-binding domain DUF5110 PF17137.4 EGR32376.1 - 0.21 11.9 2.8 1.5 9.2 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5110) FapA PF03961.13 EGR32376.1 - 1.1 7.8 18.1 0.013 14.1 7.6 1.9 1 1 1 2 2 2 0 Flagellar Assembly Protein A Pkinase PF00069.25 EGR32378.1 - 2.6e-30 105.7 7.1 2.8e-22 79.3 0.0 3.0 2 1 1 3 3 3 2 Protein kinase domain Peptidase_M14 PF00246.24 EGR32378.1 - 2.5e-21 76.7 0.0 7.6e-21 75.2 0.0 1.7 1 1 0 1 1 1 1 Zinc carboxypeptidase Pkinase_Tyr PF07714.17 EGR32378.1 - 2.1e-18 66.5 0.6 9.1e-13 48.1 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Pepdidase_M14_N PF18027.1 EGR32378.1 - 9.1e-11 42.1 3.8 1.8e-10 41.1 2.0 2.4 2 0 0 2 2 2 1 Cytosolic carboxypeptidase N-terminal domain WD40 PF00400.32 EGR32378.1 - 1.1e-10 41.9 6.1 0.041 14.8 0.5 7.7 8 0 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR32378.1 - 6.3e-07 29.6 2.5 0.022 15.0 0.0 5.6 4 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EGR32378.1 - 0.00046 20.6 0.5 14 6.3 0.0 4.3 4 0 0 4 4 4 2 PQQ-like domain AstE_AspA PF04952.14 EGR32378.1 - 0.00073 18.7 0.0 0.0012 17.9 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Methyltr_RsmB-F PF01189.17 EGR32379.1 - 6.2e-10 39.0 0.2 3.3e-09 36.7 0.2 2.2 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F DICT PF10069.9 EGR32379.1 - 0.03 14.1 3.4 1.2 8.9 0.9 2.5 2 0 0 2 2 2 0 Sensory domain in DIguanylate Cyclases and Two-component system SNF2_N PF00176.23 EGR32380.1 - 5.8e-74 248.9 1.1 5.8e-74 248.9 1.1 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGR32380.1 - 1.4e-19 70.5 0.0 1.4e-19 70.5 0.0 3.3 5 0 0 5 5 4 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 EGR32380.1 - 2.8e-08 33.4 10.4 2.8e-08 33.4 10.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) ResIII PF04851.15 EGR32380.1 - 5.1e-08 33.1 0.0 5.1e-08 33.1 0.0 4.1 4 1 0 4 4 4 1 Type III restriction enzyme, res subunit zf-C3HC4_3 PF13920.6 EGR32380.1 - 1.1e-07 31.6 10.5 2.5e-07 30.4 10.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGR32380.1 - 2.6e-05 24.0 10.7 8.9e-05 22.3 10.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DEAD PF00270.29 EGR32380.1 - 3.7e-05 23.6 0.3 0.00011 22.0 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-RING_2 PF13639.6 EGR32380.1 - 3.8e-05 23.9 10.8 3.8e-05 23.9 10.8 2.0 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 EGR32380.1 - 8.5e-05 22.3 8.6 0.00019 21.2 8.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGR32380.1 - 0.00052 19.9 9.8 0.0017 18.2 9.8 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGR32380.1 - 0.0023 17.9 8.4 0.0023 17.9 8.4 2.2 2 0 0 2 2 1 1 RING-type zinc-finger Init_tRNA_PT PF04179.12 EGR32380.1 - 0.033 14.5 0.5 0.11 12.8 0.5 2.0 1 0 0 1 1 1 0 Rit1 DUSP-like domain zf-C3HC4_4 PF15227.6 EGR32380.1 - 0.084 13.0 7.6 0.88 9.8 7.9 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EGR32380.1 - 0.89 9.5 6.8 3.3 7.7 6.0 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 EGR32380.1 - 0.94 9.8 7.8 1.7 9.0 5.5 2.5 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 EGR32380.1 - 0.96 9.3 8.8 2.6 7.9 8.8 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EGR32380.1 - 8.3 6.6 12.2 1.2 9.3 6.8 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 SLAM PF06214.11 EGR32381.1 - 0.027 14.5 0.2 0.032 14.3 0.2 1.2 1 0 0 1 1 1 0 Signaling lymphocytic activation molecule (SLAM) protein SUIM_assoc PF16619.5 EGR32382.1 - 0.031 14.3 11.6 0.036 14.1 11.6 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TMEM51 PF15345.6 EGR32382.1 - 0.12 12.2 5.9 0.13 12.1 5.9 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 UPF0524 PF15823.5 EGR32382.1 - 0.43 9.9 4.1 0.44 9.9 4.1 1.0 1 0 0 1 1 1 0 UPF0524 of C3orf70 DUF4834 PF16118.5 EGR32382.1 - 1.5 9.8 8.7 1.6 9.8 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 EGR32382.1 - 3.3 6.4 5.8 3.1 6.5 5.8 1.0 1 0 0 1 1 1 0 Presenilin SIMPL PF04402.14 EGR32383.1 - 6.7e-26 92.0 12.7 8.3e-26 91.7 12.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Translin PF01997.16 EGR32383.1 - 0.018 15.0 2.2 0.018 15.0 2.2 1.8 2 0 0 2 2 2 0 Translin family RBFA PF02033.18 EGR32383.1 - 0.097 13.1 2.6 0.15 12.5 0.4 2.2 2 0 0 2 2 2 0 Ribosome-binding factor A PC-Esterase PF13839.6 EGR32383.1 - 0.13 11.9 1.3 0.25 11.0 1.3 1.6 1 1 0 1 1 1 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DUF2408 PF10303.9 EGR32383.1 - 0.64 10.6 9.4 0.28 11.7 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Kelch_4 PF13418.6 EGR32384.1 - 1.2e-51 172.5 5.9 7.2e-12 45.1 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EGR32384.1 - 3.4e-33 113.1 7.5 5.9e-08 32.5 0.3 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 EGR32384.1 - 1.4e-31 108.1 0.2 1.5e-05 25.1 0.0 7.1 8 0 0 8 8 8 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EGR32384.1 - 7.4e-31 105.4 14.5 4.9e-07 29.8 0.0 6.7 5 2 2 7 7 7 5 Kelch motif Kelch_1 PF01344.25 EGR32384.1 - 5e-22 77.2 12.5 5e-07 29.2 0.0 6.8 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 EGR32384.1 - 6e-19 67.2 10.9 1.5e-06 27.9 0.0 6.4 6 0 0 6 6 6 6 Kelch motif EGF_2 PF07974.13 EGR32384.1 - 3.9e-09 36.7 56.8 0.0025 18.2 13.6 3.9 3 0 0 3 3 3 3 EGF-like domain EGF PF00008.27 EGR32384.1 - 1.6e-07 31.5 37.1 0.01 16.1 8.3 4.1 3 0 0 3 3 3 3 EGF-like domain EGF_Tenascin PF18720.1 EGR32384.1 - 0.031 14.3 34.9 0.094 12.8 3.0 3.5 3 0 0 3 3 3 0 Tenascin EGF domain hEGF PF12661.7 EGR32384.1 - 0.032 14.9 29.9 0.3 11.8 6.4 4.0 3 0 0 3 3 3 0 Human growth factor-like EGF Laminin_EGF PF00053.24 EGR32384.1 - 0.62 10.2 39.4 2.4 8.4 6.8 3.6 2 1 1 3 3 3 0 Laminin EGF domain DSL PF01414.19 EGR32384.1 - 2.1 8.7 36.1 0.6 10.4 18.6 2.7 2 1 0 2 2 2 0 Delta serrate ligand Strumpellin PF10266.9 EGR32385.1 - 8.9e-120 401.2 22.2 5.3e-70 236.4 5.9 2.0 1 1 1 2 2 2 2 Hereditary spastic paraplegia protein strumpellin Glyco_tranf_2_5 PF13712.6 EGR32385.1 - 0.0012 18.6 0.4 0.0028 17.4 0.4 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family Prp18 PF02840.15 EGR32386.1 - 1.3e-49 167.9 0.0 1.5e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Prp18 domain Csm1 PF12539.8 EGR32387.1 - 0.018 15.6 0.1 0.024 15.3 0.1 1.2 1 0 0 1 1 1 0 Chromosome segregation protein Csm1/Pcs1 PET PF06297.14 EGR32387.1 - 0.044 14.1 0.1 0.06 13.7 0.1 1.1 1 0 0 1 1 1 0 PET Domain Glyco_transf_54 PF04666.13 EGR32387.1 - 0.056 12.3 0.6 0.071 12.0 0.6 1.1 1 0 0 1 1 1 0 N-Acetylglucosaminyltransferase-IV (GnT-IV) conserved region Myb_DNA-binding PF00249.31 EGR32388.1 - 3.7e-38 129.5 12.2 6.4e-17 61.5 0.5 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGR32388.1 - 1.5e-32 111.6 10.6 1.3e-18 67.0 3.5 2.9 1 1 2 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 EGR32388.1 - 1.1e-06 28.6 3.8 0.011 15.8 0.2 3.9 1 1 3 4 4 4 2 SLIDE Rap1_C PF11626.8 EGR32388.1 - 0.0004 20.4 5.8 0.17 12.0 5.8 2.9 1 1 0 1 1 1 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain PRC2_HTH_1 PF18118.1 EGR32388.1 - 0.0041 17.9 2.0 0.0046 17.7 0.7 1.8 2 0 0 2 2 2 1 Polycomb repressive complex 2 tri-helical domain DUF2621 PF11084.8 EGR32388.1 - 0.0056 16.6 1.1 3.1 7.8 0.0 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF2621) Tox-GHH PF15636.6 EGR32388.1 - 0.06 13.3 4.6 1.7 8.7 0.2 3.3 3 0 0 3 3 3 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin UBA_6 PF18039.1 EGR32388.1 - 0.17 11.9 1.8 12 5.9 0.0 3.0 3 0 0 3 3 3 0 UBA-like domain SANT_DAMP1_like PF16282.5 EGR32388.1 - 0.27 11.5 12.8 2.7 8.3 0.8 3.6 3 1 1 4 4 4 0 SANT/Myb-like domain of DAMP1 PA PF02225.22 EGR32389.1 - 0.00059 19.8 0.0 0.0013 18.7 0.0 1.6 1 0 0 1 1 1 1 PA domain Thioredoxin_4 PF13462.6 EGR32389.1 - 0.0057 16.8 0.0 0.016 15.4 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin YqzE PF14038.6 EGR32389.1 - 0.019 15.0 0.1 0.052 13.5 0.1 1.8 1 0 0 1 1 1 0 YqzE-like protein m04gp34like PF12216.8 EGR32389.1 - 0.04 13.5 1.8 0.047 13.3 0.1 1.8 1 1 1 2 2 2 0 Immune evasion protein GATase_7 PF13537.6 EGR32389.1 - 0.048 13.6 0.1 0.15 12.0 0.0 1.9 2 0 0 2 2 2 0 Glutamine amidotransferase domain EphA2_TM PF14575.6 EGR32389.1 - 0.74 10.7 5.9 0.36 11.7 0.5 3.0 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain TP_methylase PF00590.20 EGR32390.1 - 2.1e-13 50.7 0.0 1.9e-07 31.2 0.0 2.3 2 0 0 2 2 2 2 Tetrapyrrole (Corrin/Porphyrin) Methylases YfcL PF08891.11 EGR32390.1 - 0.013 15.9 0.1 0.043 14.2 0.1 2.0 1 0 0 1 1 1 0 YfcL protein LSM PF01423.22 EGR32392.1 - 4.5e-21 74.3 0.3 5.1e-21 74.1 0.3 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGR32392.1 - 0.0017 18.4 0.0 0.0021 18.2 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain MORN PF02493.20 EGR32393.1 - 1.4e-14 53.0 30.7 4.3e-06 26.3 0.8 6.1 6 0 0 6 6 6 5 MORN repeat DUF1007 PF06226.13 EGR32393.1 - 0.0095 15.9 13.2 0.015 15.3 13.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1007) DHquinase_II PF01220.19 EGR32393.1 - 0.041 13.5 2.1 0.072 12.8 2.1 1.4 1 0 0 1 1 1 0 Dehydroquinase class II FixH PF05751.11 EGR32393.1 - 1.8 8.5 6.0 3.6 7.6 6.0 1.4 1 0 0 1 1 1 0 FixH eIF-4B PF06273.11 EGR32393.1 - 3.4 6.6 6.4 4.8 6.1 6.4 1.2 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B DUF3616 PF12275.8 EGR32393.1 - 9.9 5.5 11.0 15 4.9 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3616) Methyltransf_31 PF13847.6 EGR32394.1 - 4.1e-15 55.9 0.5 5.7e-15 55.4 0.5 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGR32394.1 - 1.7e-14 54.2 0.0 4.2e-14 53.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGR32394.1 - 4e-14 53.0 0.0 8.2e-14 52.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGR32394.1 - 7e-13 49.2 0.1 2.4e-12 47.5 0.0 2.0 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGR32394.1 - 2.2e-10 40.6 0.2 3.2e-10 40.1 0.2 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGR32394.1 - 0.00036 20.1 0.1 0.0006 19.4 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 EGR32394.1 - 0.0004 20.5 0.0 0.0029 17.7 0.0 2.1 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.9 EGR32394.1 - 0.00081 19.2 0.1 0.0016 18.2 0.1 1.5 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_4 PF02390.17 EGR32394.1 - 0.0031 17.0 0.3 0.43 10.0 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase CmcI PF04989.12 EGR32394.1 - 0.016 14.9 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase Methyltransf_24 PF13578.6 EGR32394.1 - 0.02 15.9 0.0 0.033 15.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_5 PF01795.19 EGR32394.1 - 0.036 13.6 0.0 1.9 7.9 0.0 2.1 1 1 1 2 2 2 0 MraW methylase family RGS_DHEX PF18148.1 EGR32394.1 - 3.9 7.7 5.4 1.8 8.7 0.1 2.7 3 0 0 3 3 3 0 Regulator of G-protein signalling DHEX domain Ubiquitin_2 PF14560.6 EGR32395.1 - 9.5e-25 86.9 2.2 2.2e-24 85.7 2.2 1.6 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 EGR32395.1 - 2.6e-22 78.6 0.3 4.1e-22 78.0 0.3 1.3 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.23 EGR32395.1 - 6.7e-07 29.0 1.9 3.1e-06 26.8 1.0 2.5 2 1 0 2 2 2 1 Ubiquitin family DUF3862 PF12978.7 EGR32395.1 - 0.028 14.2 3.6 0.05 13.4 3.6 1.5 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3862) USP7_C2 PF14533.6 EGR32395.1 - 0.1 12.3 6.5 0.022 14.4 2.2 1.8 1 1 1 2 2 2 0 Ubiquitin-specific protease C-terminal Xpo1 PF08389.12 EGR32396.1 - 1.6e-07 31.5 10.5 1.6e-07 31.5 10.5 2.8 2 1 0 2 2 2 1 Exportin 1-like protein DUF2034 PF10356.9 EGR32398.1 - 0.087 12.2 0.1 0.095 12.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) zf-CCCH PF00642.24 EGR32398.1 - 0.12 12.3 1.1 0.17 11.9 1.1 1.2 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DDRGK PF09756.9 EGR32399.1 - 2.3e-58 196.9 41.8 2.3e-58 196.9 41.8 2.6 2 1 1 3 3 3 1 DDRGK domain SpoIIIAH PF12685.7 EGR32399.1 - 0.00057 19.8 24.7 0.00057 19.8 24.7 1.8 2 0 0 2 2 2 1 SpoIIIAH-like protein Neur_chan_memb PF02932.16 EGR32399.1 - 0.11 12.5 26.1 0.24 11.4 26.1 1.8 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PRP38_assoc PF12871.7 EGR32399.1 - 0.23 12.1 26.7 0.45 11.2 26.7 1.5 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Ndc1_Nup PF09531.10 EGR32399.1 - 1.5 7.4 13.3 1.8 7.1 13.3 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1126 PF06565.12 EGR32401.1 - 1.8e-92 304.1 13.1 7.9e-37 125.3 0.5 3.4 3 0 0 3 3 3 3 DUF1126 PH-like domain EF-hand_1 PF00036.32 EGR32401.1 - 0.07 12.7 0.4 0.07 12.7 0.4 2.9 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.6 EGR32401.1 - 0.088 12.7 0.1 0.5 10.3 0.1 2.3 1 1 0 1 1 1 0 EF-hand domain pair TPR_12 PF13424.6 EGR32402.1 - 4.6e-67 222.3 26.9 4.7e-15 55.6 0.7 4.9 1 1 5 6 6 6 6 Tetratricopeptide repeat TPR_1 PF00515.28 EGR32402.1 - 1e-32 110.6 25.1 3.2e-06 26.7 2.0 7.6 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_2 PF07719.17 EGR32402.1 - 8.8e-29 97.3 15.4 2.4e-05 24.1 1.2 7.5 7 0 0 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 EGR32402.1 - 9e-26 89.0 15.6 8.9e-07 28.6 0.8 6.8 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_7 PF13176.6 EGR32402.1 - 2e-19 68.1 15.7 2.6e-05 23.9 0.1 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 EGR32402.1 - 7.2e-18 63.3 31.7 9.5e-05 22.3 1.3 7.7 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 EGR32402.1 - 1.4e-08 34.5 22.2 0.11 12.9 1.3 8.0 7 1 0 7 7 7 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGR32402.1 - 6.3e-06 26.5 10.5 0.4 11.4 0.2 5.9 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGR32402.1 - 0.00012 22.6 0.0 2.7 9.0 0.0 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGR32402.1 - 0.00015 22.4 0.0 3 8.6 0.1 4.7 6 0 0 6 6 5 1 Tetratricopeptide repeat RPW8 PF05659.11 EGR32402.1 - 0.00024 20.8 3.2 0.00024 20.8 3.2 2.7 1 1 1 2 2 2 1 Arabidopsis broad-spectrum mildew resistance protein RPW8 SHNi-TPR PF10516.9 EGR32402.1 - 0.0034 16.8 10.3 0.018 14.5 0.1 4.5 4 0 0 4 4 4 1 SHNi-TPR TPR_19 PF14559.6 EGR32402.1 - 0.0065 17.0 6.1 0.92 10.1 0.6 3.9 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGR32402.1 - 0.0075 15.7 1.1 0.2 11.0 1.3 2.1 1 1 1 2 2 2 2 MalT-like TPR region PPR PF01535.20 EGR32402.1 - 0.016 15.4 3.6 7.7 7.0 0.1 4.2 4 0 0 4 4 4 0 PPR repeat DUF627 PF04781.12 EGR32402.1 - 0.025 14.6 0.1 0.025 14.6 0.1 3.7 4 1 1 5 5 5 0 Protein of unknown function (DUF627) ANAPC3 PF12895.7 EGR32402.1 - 0.036 14.3 21.7 0.86 9.9 3.5 5.6 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EGR32402.1 - 0.08 13.0 10.3 0.08 13.0 1.7 3.9 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 EGR32402.1 - 0.14 12.2 27.5 0.72 9.9 0.7 6.2 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 EGR32402.1 - 0.21 11.9 2.8 0.58 10.5 0.4 2.9 3 1 0 3 3 3 0 Tetratricopeptide repeat NAD_Gly3P_dh_C PF07479.14 EGR32402.1 - 0.45 10.8 7.8 0.31 11.3 0.6 3.1 1 1 2 3 3 3 0 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus PAH PF02671.21 EGR32402.1 - 3.3 7.9 8.2 8.9 6.5 5.0 3.3 2 1 0 2 2 2 0 Paired amphipathic helix repeat Ribonuclease_T2 PF00445.18 EGR32402.1 - 6.3 7.0 16.5 3.5 7.8 6.8 3.2 1 1 1 2 2 2 0 Ribonuclease T2 family MutS_V PF00488.21 EGR32403.1 - 9.3e-72 241.0 0.1 1.8e-71 240.1 0.1 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGR32403.1 - 2e-27 96.7 1.2 2e-27 96.7 1.2 2.3 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EGR32403.1 - 6.1e-16 58.7 0.9 1.8e-15 57.2 0.9 1.9 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.18 EGR32403.1 - 5.2e-09 36.3 2.8 3.6e-08 33.6 2.8 2.6 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 EGR32403.1 - 0.065 13.5 7.9 0.093 13.0 3.8 3.2 2 1 0 2 2 2 0 MutS domain II AAA_29 PF13555.6 EGR32403.1 - 0.14 11.9 0.0 0.37 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_28 PF13521.6 EGR32403.1 - 0.14 12.4 0.0 0.39 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain CxC7 PF18866.1 EGR32404.1 - 0.011 15.9 3.9 0.046 13.9 2.7 2.6 1 1 1 2 2 2 0 CxC7 like cysteine cluster associated with KDZ transposases Peptidase_M8 PF01457.16 EGR32405.1 - 9.2e-14 51.0 0.1 1.6e-13 50.2 0.1 1.4 1 0 0 1 1 1 1 Leishmanolysin EGF_Tenascin PF18720.1 EGR32405.1 - 8.2e-07 28.9 7.0 8.2e-07 28.9 7.0 3.1 3 0 0 3 3 3 1 Tenascin EGF domain EGF_2 PF07974.13 EGR32405.1 - 0.0055 17.0 10.6 0.018 15.4 10.6 1.9 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 EGR32405.1 - 0.042 14.1 12.0 0.11 12.9 12.0 1.8 1 0 0 1 1 1 0 EGF-like domain Phospholamban PF04272.14 EGR32407.1 - 0.044 13.3 0.4 0.98 8.9 0.1 2.9 1 1 1 2 2 2 0 Phospholamban DUF1137 PF06587.11 EGR32407.1 - 0.054 13.5 0.5 0.75 9.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1137) DUF826 PF05696.11 EGR32408.1 - 1.8 8.7 4.7 2.5 8.2 0.9 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF826) Pyr_redox_2 PF07992.14 EGR32409.1 - 5.5e-66 222.8 2.9 8.5e-66 222.2 2.9 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGR32409.1 - 6.9e-35 119.6 0.4 1.6e-34 118.5 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGR32409.1 - 6.9e-21 74.6 4.4 1.2e-17 64.3 0.2 3.2 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGR32409.1 - 1.8e-13 50.7 0.1 1.4e-10 41.1 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGR32409.1 - 3.8e-11 42.8 9.4 1.5e-08 34.2 0.4 2.7 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGR32409.1 - 2.5e-10 40.0 11.2 2.9e-09 36.5 4.0 3.1 2 2 1 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EGR32409.1 - 4.4e-10 39.2 13.2 1.9e-07 30.5 2.6 4.2 2 1 2 4 4 4 2 FAD binding domain NAD_binding_8 PF13450.6 EGR32409.1 - 5.7e-09 36.1 1.6 0.00011 22.3 0.4 2.5 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGR32409.1 - 5.8e-09 35.1 6.7 0.00012 20.9 1.5 4.2 4 0 0 4 4 4 3 HI0933-like protein AlaDh_PNT_C PF01262.21 EGR32409.1 - 4.8e-07 29.3 0.9 0.0059 15.9 0.0 2.7 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 EGR32409.1 - 3.4e-06 26.5 6.7 0.011 15.0 0.6 3.1 2 1 1 3 3 3 3 FAD binding domain DAO PF01266.24 EGR32409.1 - 8.8e-05 22.2 8.6 0.28 10.7 0.5 3.3 3 0 0 3 3 3 3 FAD dependent oxidoreductase Thi4 PF01946.17 EGR32409.1 - 9.4e-05 21.8 5.7 0.0004 19.7 0.9 2.5 2 1 0 2 2 2 1 Thi4 family K_oxygenase PF13434.6 EGR32409.1 - 0.0025 17.0 0.1 0.69 9.0 0.0 2.8 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Lycopene_cycl PF05834.12 EGR32409.1 - 0.0037 16.4 1.8 1.6 7.7 1.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein 3HCDH_N PF02737.18 EGR32409.1 - 0.053 13.4 2.2 0.056 13.3 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 EGR32409.1 - 0.072 13.6 0.0 2.4 8.7 0.0 2.3 2 0 0 2 2 2 0 XdhC Rossmann domain UDPG_MGDP_dh_N PF03721.14 EGR32409.1 - 0.9 9.1 4.3 0.27 10.8 0.3 2.1 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Pkinase PF00069.25 EGR32411.1 - 9.9e-76 254.6 1.4 9.9e-76 254.6 1.4 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32411.1 - 7e-47 159.9 0.2 1.2e-46 159.2 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR32411.1 - 4.2e-07 29.6 0.0 1.6e-06 27.6 0.0 2.0 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EGR32411.1 - 0.0018 17.7 1.3 0.0026 17.2 0.0 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR32411.1 - 0.0091 15.9 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family RL PF17797.1 EGR32411.1 - 0.03 14.3 0.1 0.085 12.8 0.1 1.8 1 0 0 1 1 1 0 RL domain Ion_trans PF00520.31 EGR32413.1 - 8.6e-05 21.9 1.8 8.6e-05 21.9 1.8 1.5 2 0 0 2 2 2 1 Ion transport protein Ribosomal_S11 PF00411.19 EGR32414.1 - 2.8e-42 143.6 0.1 3.5e-42 143.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 YtxH PF12732.7 EGR32415.1 - 1.2 9.7 15.2 4.2 8.0 0.9 3.8 2 1 0 2 2 2 0 YtxH-like protein MFS_1 PF07690.16 EGR32416.1 - 2.9e-24 85.7 9.2 3.5e-24 85.4 9.2 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily PUCC PF03209.15 EGR32416.1 - 0.017 14.1 3.7 0.026 13.6 3.7 1.2 1 0 0 1 1 1 0 PUCC protein Cytochrome-c551 PF10643.9 EGR32416.1 - 0.11 12.1 3.2 0.24 10.9 3.2 1.5 1 0 0 1 1 1 0 Photosystem P840 reaction-centre cytochrome c-551 FHA PF00498.26 EGR32417.1 - 0.27 11.6 3.9 0.68 10.3 0.0 3.1 3 1 0 3 3 3 0 FHA domain Scramblase PF03803.15 EGR32419.1 - 1.6e-19 70.1 2.9 2.3e-19 69.6 2.9 1.2 1 0 0 1 1 1 1 Scramblase PRC PF05239.16 EGR32419.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 PRC-barrel domain HEV_ORF1 PF02444.16 EGR32419.1 - 7 7.3 8.6 1.9 9.1 4.4 2.0 2 0 0 2 2 2 0 Hepatitis E virus ORF-2 (Putative capsid protein) SNARE_assoc PF09335.11 EGR32420.1 - 0.011 16.2 0.8 0.053 14.0 0.0 2.2 1 1 1 2 2 2 0 SNARE associated Golgi protein OsmC PF02566.19 EGR32422.1 - 1.9e-15 57.2 0.0 2.6e-15 56.7 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein RCC1 PF00415.18 EGR32423.1 - 3.9e-32 110.6 10.1 2.5e-14 53.6 0.0 6.2 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR32423.1 - 3.4e-18 64.9 11.0 1.1e-06 28.3 1.4 4.8 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat DUF4460 PF14687.6 EGR32424.1 - 6e-17 61.7 2.6 6e-17 61.7 2.6 2.1 2 1 1 3 3 3 1 Domain of unknown function (DUF4460) L27_1 PF09058.10 EGR32424.1 - 1.8 8.6 8.2 4.2 7.4 1.8 3.5 3 1 0 3 3 3 0 L27_1 DUF3095 PF11294.8 EGR32424.1 - 2.3 7.2 5.8 0.36 9.9 1.6 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3095) PMC2NT PF08066.12 EGR32424.1 - 5.6 7.7 6.5 4.6 8.0 0.2 3.2 2 2 1 3 3 3 0 PMC2NT (NUC016) domain Pkinase PF00069.25 EGR32425.1 - 2.7e-15 56.5 0.1 2.7e-15 56.5 0.1 1.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_fungal PF17667.1 EGR32425.1 - 4.8e-12 45.4 1.2 5.7e-12 45.1 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Pkinase_Tyr PF07714.17 EGR32425.1 - 3.5e-08 33.0 0.0 6.6e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR32425.1 - 0.011 15.1 0.1 0.024 14.0 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RPN6_N PF18055.1 EGR32426.1 - 7e-28 97.3 5.9 7e-28 97.3 5.9 3.6 3 1 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EGR32426.1 - 1.9e-16 60.4 3.6 1.9e-16 60.4 3.6 3.3 3 1 0 3 3 3 1 PCI domain ANAPC5 PF12862.7 EGR32426.1 - 0.064 13.3 3.3 5.1 7.2 0.2 2.7 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 5 G-gamma PF00631.22 EGR32426.1 - 0.098 12.7 1.2 0.94 9.5 0.1 2.8 2 0 0 2 2 2 0 GGL domain Pico_P2B PF01552.17 EGR32426.1 - 0.1 12.8 3.3 0.41 10.8 0.1 3.2 3 1 1 4 4 4 0 Picornavirus 2B protein TPR_12 PF13424.6 EGR32426.1 - 0.11 12.8 11.2 1.9 8.8 2.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Autophagy_N PF03986.13 EGR32426.1 - 0.13 12.3 0.9 0.3 11.0 0.9 1.6 1 0 0 1 1 1 0 Autophagocytosis associated protein (Atg3), N-terminal domain PIP5K PF01504.18 EGR32427.1 - 2.4e-59 200.8 11.9 3.4e-59 200.3 11.9 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF1416 PF07210.12 EGR32427.1 - 0.027 14.4 0.0 0.059 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) EF-hand_6 PF13405.6 EGR32428.1 - 0.0032 17.3 0.8 1.4 9.1 0.0 3.2 3 0 0 3 3 3 1 EF-hand domain EF-hand_7 PF13499.6 EGR32428.1 - 0.008 16.6 0.1 0.024 15.1 0.0 1.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.32 EGR32428.1 - 0.013 15.0 0.7 0.57 9.9 0.2 2.5 2 0 0 2 2 2 0 EF hand NADPH_Ox PF08414.10 EGR32428.1 - 0.081 13.3 0.2 0.38 11.1 0.1 1.9 1 1 1 2 2 2 0 Respiratory burst NADPH oxidase SMK-1 PF04802.15 EGR32429.1 - 4e-11 43.1 2.6 5.5e-11 42.7 2.6 1.2 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 SabA_adhesion PF18304.1 EGR32429.1 - 0.041 13.1 2.8 3 7.0 0.5 2.0 1 1 1 2 2 2 0 SabA N-terminal extracellular adhesion domain DUF3195 PF11424.8 EGR32429.1 - 3.7 7.7 6.4 1.9 8.6 0.5 2.6 1 1 1 3 3 3 0 Protein of unknown function (DUF3195) zf-CCCH PF00642.24 EGR32430.1 - 0.13 12.2 0.1 0.13 12.2 0.1 5.8 8 0 0 8 8 8 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pkinase PF00069.25 EGR32431.1 - 5.7e-64 216.0 1.1 5.7e-64 216.0 1.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32431.1 - 3.5e-40 137.9 0.3 6e-40 137.2 0.3 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR32431.1 - 8.7e-05 22.0 0.2 0.00056 19.3 0.0 2.1 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 EGR32431.1 - 0.00013 21.7 2.3 0.00014 21.5 0.4 2.1 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 EGR32431.1 - 0.003 16.9 0.2 0.0072 15.7 0.2 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EGR32431.1 - 0.011 15.3 3.7 0.016 14.8 0.3 3.0 2 1 1 3 3 3 0 PhoP regulatory network protein YrbL Sec1 PF00995.23 EGR32432.1 - 1.1e-59 203.2 23.8 3.7e-43 148.6 14.2 2.0 1 1 1 2 2 2 2 Sec1 family FliP PF00813.20 EGR32432.1 - 0.28 11.1 2.0 0.44 10.4 0.6 2.0 1 1 1 2 2 2 0 FliP family Methyltransf_15 PF09445.10 EGR32432.1 - 1.3 8.6 7.6 15 5.1 4.2 2.8 1 1 1 2 2 2 0 RNA cap guanine-N2 methyltransferase Topoisom_I PF01028.20 EGR32433.1 - 9.3e-93 309.7 16.1 9.3e-93 309.7 16.1 2.7 3 0 0 3 3 3 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EGR32433.1 - 4.4e-75 251.9 8.9 4.4e-75 251.9 8.9 4.6 3 1 1 4 4 4 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EGR32433.1 - 7.4e-30 102.7 3.7 2.7e-29 100.9 3.7 2.1 1 0 0 1 1 1 1 C-terminal topoisomerase domain MORN PF02493.20 EGR32434.1 - 9.7e-34 113.3 56.4 3.1e-06 26.7 1.2 9.9 10 0 0 10 10 10 8 MORN repeat Response_reg PF00072.24 EGR32434.1 - 8.1e-08 32.4 0.0 1.2e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Response regulator receiver domain ARID PF01388.21 EGR32435.1 - 0.06 14.0 0.1 0.09 13.5 0.1 1.5 1 1 0 1 1 1 0 ARID/BRIGHT DNA binding domain TPR_12 PF13424.6 EGR32436.1 - 1.5e-17 63.6 1.6 1.9e-15 56.9 0.1 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGR32436.1 - 9e-08 31.8 0.1 0.0002 21.1 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGR32436.1 - 1.6e-05 24.5 2.8 0.0002 21.1 0.4 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGR32436.1 - 6e-05 22.8 2.4 0.027 14.6 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGR32436.1 - 0.015 15.5 1.7 0.16 12.3 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat GTP_EFTU PF00009.27 EGR32437.1 - 6e-54 182.5 0.0 7.8e-54 182.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGR32437.1 - 3.2e-41 140.1 0.1 7.8e-41 138.9 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGR32437.1 - 1.3e-14 54.3 0.2 5.5e-14 52.3 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGR32437.1 - 6.2e-06 26.3 0.1 0.001 19.1 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EGR32437.1 - 0.00069 19.5 0.5 0.00069 19.5 0.5 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 FeoB_N PF02421.18 EGR32437.1 - 0.073 12.6 0.4 0.27 10.8 0.0 2.1 2 1 0 2 2 2 0 Ferrous iron transport protein B G-alpha PF00503.20 EGR32437.1 - 0.19 10.9 0.3 2.8 7.0 0.1 2.3 1 1 0 2 2 2 0 G-protein alpha subunit Kelch_5 PF13854.6 EGR32438.1 - 1.2e-32 111.3 4.0 2.9e-06 27.1 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Metallophos PF00149.28 EGR32438.1 - 2.4e-30 106.6 1.7 2.4e-30 106.6 1.7 2.7 3 1 1 4 4 4 1 Calcineurin-like phosphoesterase Kelch_4 PF13418.6 EGR32438.1 - 6.3e-29 99.7 19.8 7.8e-12 45.0 0.2 7.2 6 1 1 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EGR32438.1 - 7.8e-29 99.4 6.1 1.1e-06 28.8 0.0 7.6 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EGR32438.1 - 7.7e-18 64.1 10.0 0.0027 17.9 0.0 6.7 4 2 2 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EGR32438.1 - 1.2e-13 50.4 7.6 0.021 14.8 0.0 6.7 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 EGR32438.1 - 1.6e-07 30.8 10.2 0.00041 19.9 0.0 5.7 5 1 1 6 6 6 2 Kelch motif RAG2 PF03089.14 EGR32438.1 - 3.2e-07 29.7 0.1 0.34 9.9 0.0 3.7 3 1 1 4 4 4 3 Recombination activating protein 2 STPPase_N PF16891.5 EGR32438.1 - 0.00057 20.3 0.3 0.0013 19.2 0.3 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain TFIIA PF03153.13 EGR32438.1 - 0.17 11.9 16.0 0.24 11.4 16.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRR_9 PF14580.6 EGR32439.1 - 1.9e-18 66.6 8.7 2.3e-18 66.3 8.7 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EGR32439.1 - 0.0002 21.6 27.4 0.0031 17.9 3.5 4.1 3 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGR32439.1 - 0.00043 20.0 21.0 0.048 13.4 5.9 3.7 1 1 3 4 4 4 4 Leucine rich repeat SDA1 PF05285.12 EGR32439.1 - 0.04 13.3 41.4 0.051 13.0 41.4 1.1 1 0 0 1 1 1 0 SDA1 Mpp10 PF04006.12 EGR32439.1 - 0.084 11.3 30.3 0.11 10.9 30.3 1.2 1 0 0 1 1 1 0 Mpp10 protein CDC45 PF02724.14 EGR32439.1 - 0.16 10.2 28.4 0.23 9.7 28.4 1.3 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EGR32439.1 - 0.49 8.5 45.2 0.13 10.4 40.9 1.8 2 0 0 2 2 2 0 Nop14-like family BRO1 PF03097.18 EGR32440.1 - 2.8e-30 105.4 15.3 3.5e-30 105.1 15.3 1.1 1 0 0 1 1 1 1 BRO1-like domain MIT PF04212.18 EGR32440.1 - 1.5 8.9 7.2 0.46 10.6 0.5 3.0 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain SET PF00856.28 EGR32441.1 - 9.5e-15 55.4 0.3 3.5e-14 53.5 0.1 2.1 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 EGR32441.1 - 0.0029 18.3 0.1 0.0054 17.4 0.1 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding MFS_1 PF07690.16 EGR32442.1 - 3.3e-35 121.7 13.5 3.3e-35 121.7 13.5 1.6 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 EGR32442.1 - 4.8e-08 32.0 8.7 4.8e-08 32.0 8.7 2.9 1 1 2 3 3 3 2 MFS/sugar transport protein Sugar_tr PF00083.24 EGR32442.1 - 2.7e-05 23.2 24.8 0.00018 20.5 1.3 3.3 1 1 3 4 4 4 2 Sugar (and other) transporter MORN PF02493.20 EGR32443.1 - 4.3e-44 145.8 68.8 2.1e-08 33.6 1.8 10.0 10 0 0 10 10 10 9 MORN repeat MORN PF02493.20 EGR32445.1 - 5.8e-53 173.7 124.4 1.4e-07 31.0 0.5 16.1 17 1 0 17 17 17 13 MORN repeat DUF3048_C PF17479.2 EGR32445.1 - 0.08 13.3 32.2 0.24 11.8 2.6 6.6 1 1 5 7 7 7 0 Protein of unknown function (DUF3048) C-terminal domain TRM13 PF05206.14 EGR32446.1 - 4e-11 43.0 0.1 4e-11 43.0 0.1 2.6 2 1 1 3 3 3 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 EGR32446.1 - 2.1e-07 30.6 7.0 3.7e-07 29.8 7.0 1.5 1 0 0 1 1 1 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 EGR32446.1 - 2.9e-07 30.2 2.4 5.9e-07 29.3 1.3 2.1 2 0 0 2 2 2 1 U11-48K-like CHHC zinc finger Methyltransf_32 PF13679.6 EGR32446.1 - 0.079 12.9 0.2 0.079 12.9 0.2 2.5 1 1 1 2 2 2 0 Methyltransferase domain Sugar_tr PF00083.24 EGR32447.1 - 2e-18 66.5 11.4 9.1e-18 64.3 11.4 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGR32447.1 - 7e-17 61.4 14.4 2.9e-16 59.3 9.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UCH PF00443.29 EGR32448.1 - 3e-36 125.2 7.6 1.5e-35 122.9 7.6 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EGR32448.1 - 6.4e-21 74.5 2.6 6.4e-21 74.5 2.6 3.2 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UBA PF00627.31 EGR32448.1 - 1.1e-14 54.0 6.1 1.6e-11 43.9 0.3 2.9 3 0 0 3 3 3 2 UBA/TS-N domain UCH_1 PF13423.6 EGR32448.1 - 2.7e-13 50.2 19.7 5.5e-10 39.3 7.8 3.5 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase CUE PF02845.16 EGR32448.1 - 7.8e-05 22.3 3.9 0.1 12.4 0.0 3.6 3 0 0 3 3 3 2 CUE domain UBA_3 PF09288.10 EGR32448.1 - 0.0017 18.2 0.5 0.19 11.6 0.1 3.1 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain HBS1_N PF08938.10 EGR32448.1 - 0.0053 17.0 1.1 1.4 9.2 0.1 3.5 3 0 0 3 3 3 1 HBS1 N-terminus Arena_ncap_C PF17290.2 EGR32448.1 - 0.021 14.2 0.0 0.078 12.3 0.0 1.9 2 0 0 2 2 2 0 Arenavirus nucleocapsid C-terminal domain zf-UBP_var PF17807.1 EGR32448.1 - 0.038 13.7 1.0 3.5 7.5 0.2 2.8 2 0 0 2 2 2 0 Variant UBP zinc finger SHIPPO-rpt PF07004.12 EGR32449.1 - 4.1e-07 30.6 18.1 0.43 11.6 0.5 5.7 5 1 0 5 5 5 4 Sperm-tail PG-rich repeat Myb_DNA-bind_6 PF13921.6 EGR32450.1 - 2.2e-13 50.2 1.3 6e-07 29.6 0.1 2.4 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGR32450.1 - 3.2e-13 49.7 0.3 2.7e-10 40.3 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Presenilin PF01080.17 EGR32450.1 - 6.7 5.4 8.1 8.1 5.1 8.1 1.1 1 0 0 1 1 1 0 Presenilin Metallophos PF00149.28 EGR32452.1 - 7.7e-39 134.3 0.2 1e-38 133.9 0.2 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGR32452.1 - 0.00012 22.4 0.9 0.00023 21.5 0.9 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EGR32452.1 - 0.023 14.9 0.0 0.035 14.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain DUF1908 PF08926.11 EGR32452.1 - 0.11 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) YqzH PF14164.6 EGR32452.1 - 0.26 11.4 1.7 0.61 10.2 0.8 2.0 2 0 0 2 2 2 0 YqzH-like protein TPR_2 PF07719.17 EGR32453.1 - 3.8e-12 45.3 23.7 0.0012 18.8 0.0 9.0 10 1 1 11 11 9 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGR32453.1 - 1.1e-10 41.9 16.1 0.0034 17.9 0.3 6.4 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGR32453.1 - 3.5e-10 40.0 1.3 0.17 12.2 0.1 6.4 6 1 2 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGR32453.1 - 5.4e-07 30.2 0.0 0.24 12.1 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGR32453.1 - 5.4e-07 29.9 0.1 0.39 11.7 0.0 4.6 3 1 1 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR32453.1 - 5.3e-06 26.6 19.2 0.022 15.0 0.2 4.4 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.6 EGR32453.1 - 7.2e-06 25.7 5.9 0.17 12.0 0.1 5.9 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGR32453.1 - 2.4e-05 24.7 13.5 0.0021 18.6 0.1 6.3 8 0 0 8 8 5 1 Tetratricopeptide repeat ATP13 PF12921.7 EGR32453.1 - 6.2e-05 22.8 3.6 0.03 14.2 0.2 2.8 2 1 0 2 2 2 2 Mitochondrial ATPase expression Wzy_C_2 PF11846.8 EGR32453.1 - 0.00055 19.9 0.7 0.022 14.7 0.1 2.8 3 0 0 3 3 3 1 Virulence factor membrane-bound polymerase, C-terminal TPR_1 PF00515.28 EGR32453.1 - 0.00086 19.0 26.1 0.47 10.3 0.1 8.2 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_21 PF09976.9 EGR32453.1 - 0.0026 17.5 5.0 0.054 13.2 0.0 3.2 3 2 1 4 4 4 1 Tetratricopeptide repeat-like domain TPR_10 PF13374.6 EGR32453.1 - 0.034 14.0 3.7 68 3.5 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGR32453.1 - 0.093 13.0 18.4 1.4 9.3 0.1 7.0 8 0 0 8 8 7 0 Tetratricopeptide repeat DUF3808 PF10300.9 EGR32453.1 - 0.81 8.3 15.9 0.011 14.5 3.4 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3808) DUF4473 PF14747.6 EGR32453.1 - 1 10.0 4.0 1.5 9.4 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) AATF-Che1 PF13339.6 EGR32453.1 - 1.9 9.1 5.5 1.7 9.3 0.7 2.9 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor Ribosomal_S21 PF01165.20 EGR32453.1 - 2.3 8.0 5.2 28 4.5 0.1 4.0 4 0 0 4 4 4 0 Ribosomal protein S21 TPR_17 PF13431.6 EGR32453.1 - 2.4 8.7 5.4 67 4.2 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat RPN6_N PF18055.1 EGR32453.1 - 2.7 8.4 8.6 1.9 8.9 0.1 3.8 4 0 0 4 4 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain Peptidase_M8 PF01457.16 EGR32455.1 - 6.2e-31 107.7 14.1 5.6e-29 101.2 0.5 2.9 2 1 1 3 3 3 2 Leishmanolysin VSP PF03302.13 EGR32455.1 - 1.4e-06 27.4 37.2 1.4e-06 27.4 37.2 3.1 2 1 1 3 3 3 2 Giardia variant-specific surface protein EGF_Tenascin PF18720.1 EGR32455.1 - 1.3e-05 25.1 7.9 1.3e-05 25.1 7.9 4.5 5 1 0 5 5 5 1 Tenascin EGF domain EGF_2 PF07974.13 EGR32455.1 - 0.0046 17.3 13.8 0.0046 17.3 13.8 7.0 7 3 0 7 7 7 1 EGF-like domain Furin-like_2 PF15913.5 EGR32455.1 - 0.017 15.3 16.6 0.017 15.3 16.6 6.3 2 2 3 5 5 5 0 Furin-like repeat, cysteine-rich Serum_albumin PF00273.20 EGR32456.1 - 0.0056 16.5 3.6 0.078 12.7 0.6 2.1 1 1 1 2 2 2 2 Serum albumin family YniB PF14002.6 EGR32456.1 - 0.0065 16.2 0.7 0.0065 16.2 0.7 1.6 1 1 0 1 1 1 1 YniB-like protein VSP PF03302.13 EGR32457.1 - 1.7e-08 33.8 38.0 1.7e-08 33.8 38.0 3.1 2 1 1 3 3 3 2 Giardia variant-specific surface protein EGF_Tenascin PF18720.1 EGR32457.1 - 1e-05 25.4 8.1 1e-05 25.4 8.1 5.2 7 0 0 7 7 7 1 Tenascin EGF domain EGF_2 PF07974.13 EGR32457.1 - 7.3e-05 23.0 10.2 7.3e-05 23.0 10.2 7.4 5 2 0 5 5 5 1 EGF-like domain Furin-like_2 PF15913.5 EGR32457.1 - 0.0033 17.5 18.2 0.0033 17.5 18.2 6.5 1 1 3 5 5 5 3 Furin-like repeat, cysteine-rich Pkinase PF00069.25 EGR32458.1 - 3.2e-70 236.5 0.5 4.9e-70 235.9 0.5 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32458.1 - 2.1e-44 151.7 0.1 3e-44 151.3 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR32458.1 - 3.6e-06 26.0 0.0 5.9e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EGR32458.1 - 0.00022 20.9 0.2 0.00022 20.9 0.2 1.7 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 EGR32458.1 - 0.00027 20.4 0.2 0.028 13.7 0.0 2.6 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGR32458.1 - 0.00077 18.9 0.1 0.0011 18.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR32458.1 - 0.007 16.3 0.0 0.094 12.6 0.1 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family EF-hand_1 PF00036.32 EGR32460.1 - 0.0095 15.4 1.0 0.033 13.7 0.0 2.6 2 0 0 2 2 2 1 EF hand Styelin PF17562.2 EGR32460.1 - 0.035 14.5 0.0 0.14 12.5 0.0 2.0 1 0 0 1 1 1 0 Styelin DUF3910 PF13049.6 EGR32460.1 - 0.038 14.3 0.2 0.038 14.3 0.2 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3910) Zip PF02535.22 EGR32461.1 - 2.1e-41 142.2 2.8 2.7e-41 141.9 2.8 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Connexin PF00029.19 EGR32461.1 - 0.019 14.8 1.5 0.019 14.8 1.5 1.8 2 0 0 2 2 2 0 Connexin Ribosomal_L6e PF01159.19 EGR32461.1 - 0.061 13.9 7.3 0.1 13.1 7.3 1.3 1 0 0 1 1 1 0 Ribosomal protein L6e TP53IP5 PF15331.6 EGR32461.1 - 0.8 9.8 6.8 1.2 9.3 6.8 1.1 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Phage_holin_3_6 PF07332.11 EGR32461.1 - 2.6 8.1 5.8 11 6.1 1.1 3.3 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Zip PF02535.22 EGR32462.1 - 1.4e-06 27.8 7.4 3.8e-06 26.3 7.4 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter NADase_NGA PF07461.11 EGR32462.1 - 0.02 13.8 0.5 0.024 13.6 0.5 1.1 1 0 0 1 1 1 0 Nicotine adenine dinucleotide glycohydrolase (NADase) MtmB PF05369.12 EGR32462.1 - 0.033 13.0 0.1 0.045 12.5 0.1 1.2 1 0 0 1 1 1 0 Monomethylamine methyltransferase MtmB TRCF PF03461.15 EGR32462.1 - 0.033 14.6 3.3 0.049 14.0 3.3 1.3 1 0 0 1 1 1 0 TRCF domain DUF4037 PF13228.6 EGR32462.1 - 0.072 13.9 0.6 0.12 13.2 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4037) Exonuc_VII_L PF02601.15 EGR32462.1 - 0.11 12.0 5.4 0.11 12.0 5.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Zip PF02535.22 EGR32463.1 - 3.5e-17 62.6 4.3 4.4e-17 62.3 4.3 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter VSP PF03302.13 EGR32464.1 - 5.9e-05 22.1 55.9 0.0024 16.8 35.6 2.4 1 1 1 2 2 2 2 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EGR32464.1 - 0.43 10.7 54.5 0.63 10.2 10.4 4.1 1 1 3 4 4 4 0 Furin-like repeat, cysteine-rich VSP PF03302.13 EGR32465.1 - 3.4e-06 26.2 51.2 0.0054 15.6 32.6 2.8 1 1 1 2 2 2 2 Giardia variant-specific surface protein MORN PF02493.20 EGR32466.1 - 3.3e-30 102.2 87.9 1.5e-05 24.6 5.3 14.3 14 0 0 14 14 14 11 MORN repeat GrpE PF01025.19 EGR32467.1 - 3.3e-37 127.7 6.8 4.8e-37 127.2 6.8 1.3 1 1 0 1 1 1 1 GrpE Swi5 PF07061.11 EGR32467.1 - 0.06 13.4 3.5 2.4 8.3 0.0 2.8 2 1 1 3 3 3 0 Swi5 Laminin_II PF06009.12 EGR32467.1 - 0.47 10.5 4.9 2.2 8.3 4.9 2.0 1 1 0 1 1 1 0 Laminin Domain II Mito_carr PF00153.27 EGR32468.1 - 6.1e-68 224.8 2.7 1.1e-22 79.7 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EGR32468.1 - 2.8e-22 78.9 11.1 9.7e-12 45.2 3.7 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR32468.1 - 5.6e-16 57.0 16.1 0.00024 20.8 0.3 4.7 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGR32468.1 - 1e-15 57.3 7.9 6.2e-06 26.0 0.8 4.2 1 1 3 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 EGR32468.1 - 7.6e-15 53.3 19.5 3.3e-05 23.1 0.2 5.0 5 0 0 5 5 5 4 EF hand EF-hand_5 PF13202.6 EGR32468.1 - 2.7e-12 45.6 15.7 3.4e-05 23.1 0.2 4.6 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.9 EGR32468.1 - 5.9e-08 33.0 3.8 2.4e-05 24.6 1.2 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Sigma70_r1_1 PF03979.14 EGR32468.1 - 0.0038 17.2 1.7 0.01 15.9 0.9 2.2 1 1 1 2 2 2 1 Sigma-70 factor, region 1.1 EF-hand_4 PF12763.7 EGR32468.1 - 0.0045 16.9 7.3 0.015 15.2 2.9 2.4 1 1 1 2 2 2 1 Cytoskeletal-regulatory complex EF hand Tim17 PF02466.19 EGR32468.1 - 0.036 14.4 1.4 0.088 13.2 0.4 2.1 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family DUF3848 PF12959.7 EGR32468.1 - 0.097 12.7 1.0 4.5 7.4 0.4 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3848) EF-hand_10 PF14788.6 EGR32468.1 - 0.098 12.5 9.1 1 9.3 0.3 3.6 3 1 1 4 4 4 0 EF hand CPSase_L_D3 PF02787.19 EGR32468.1 - 0.12 12.7 0.8 0.27 11.6 0.8 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain ACT_3 PF10000.9 EGR32469.1 - 6.4e-05 22.8 0.2 2.1 8.4 0.0 4.1 4 0 0 4 4 4 2 ACT domain DUF4382 PF14321.6 EGR32469.1 - 0.00046 20.4 5.3 21 5.4 0.0 5.1 4 2 1 5 5 5 1 Domain of unknown function (DUF4382) RicinB_lectin_2 PF14200.6 EGR32469.1 - 0.0048 17.6 6.9 0.14 12.9 0.5 3.9 1 1 3 5 5 5 2 Ricin-type beta-trefoil lectin domain-like ATPgrasp_YheCD PF14398.6 EGR32469.1 - 0.0069 15.7 10.7 4 6.6 0.1 4.9 4 1 1 5 5 5 2 YheC/D like ATP-grasp DUF3804 PF12707.7 EGR32469.1 - 0.011 15.5 0.4 0.94 9.2 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3804) Inhibitor_I66 PF16850.5 EGR32469.1 - 0.052 13.4 2.3 1.2 8.9 0.3 3.0 1 1 0 2 2 2 0 Peptidase inhibitor I66 DUF3019 PF11456.8 EGR32469.1 - 0.11 13.0 4.4 0.53 10.8 0.3 3.4 4 1 0 4 4 4 0 Protein of unknown function (DUF3019) Phage_NinH PF06322.11 EGR32469.1 - 3.7 7.5 4.8 72 3.4 0.0 4.4 6 0 0 6 6 6 0 Phage NinH protein CDPS PF16715.5 EGR32470.1 - 6.4e-11 42.3 0.0 8.1e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 Cyclodipeptide synthase CdiA_C PF18451.1 EGR32470.1 - 0.0058 16.8 3.7 0.21 11.8 0.1 2.5 1 1 1 2 2 2 2 Contact-dependent growth inhibition CdiA C-terminal domain CSN7a_helixI PF18392.1 EGR32470.1 - 0.38 10.7 2.5 1.4 8.9 0.0 2.7 3 0 0 3 3 3 0 COP9 signalosome complex subunit 7a helix I domain DUF4464 PF14713.6 EGR32471.1 - 7e-23 81.4 7.9 8.1e-23 81.2 7.9 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) Sel_put PF04328.13 EGR32471.1 - 0.038 14.0 3.3 0.054 13.5 0.4 2.2 1 1 1 2 2 2 0 Selenoprotein, putative CSRNP_N PF16019.5 EGR32471.1 - 0.079 12.9 5.0 0.088 12.7 5.0 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus PIN_12 PF16289.5 EGR32471.1 - 0.16 12.5 8.4 0.2 12.1 8.4 1.1 1 0 0 1 1 1 0 PIN domain AAT PF03417.16 EGR32471.1 - 0.59 9.8 6.9 6.2 6.4 0.0 2.0 1 1 1 2 2 2 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase ANAPC_CDC26 PF10471.9 EGR32471.1 - 1.2 10.0 10.5 12 6.8 10.5 2.1 1 1 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 FoP_duplication PF13865.6 EGR32472.1 - 0.0069 16.9 6.7 0.0074 16.8 6.7 1.1 1 0 0 1 1 1 1 C-terminal duplication domain of Friend of PRMT1 Ras PF00071.22 EGR32473.1 - 1.1e-62 210.4 3.5 1.4e-62 210.1 3.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR32473.1 - 2.6e-33 114.8 0.9 2.6e-33 114.8 0.9 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR32473.1 - 1.4e-16 60.5 0.8 1.8e-16 60.1 0.8 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGR32473.1 - 2.8e-08 33.4 1.0 3.8e-08 33.0 0.9 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGR32473.1 - 7.5e-07 29.2 0.9 0.0058 16.6 0.2 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGR32473.1 - 1.3e-05 25.2 0.1 2.6e-05 24.3 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGR32473.1 - 2.6e-05 23.9 0.4 5e-05 22.9 0.4 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGR32473.1 - 4.6e-05 23.0 2.1 0.00017 21.2 2.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_5 PF07728.14 EGR32473.1 - 0.0071 16.4 0.3 0.036 14.1 0.0 2.1 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EGR32473.1 - 0.012 15.2 0.1 0.026 14.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 EGR32473.1 - 0.012 15.8 0.2 0.81 10.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain CENP-M PF11111.8 EGR32473.1 - 0.021 14.0 0.1 0.037 13.2 0.1 1.4 1 1 0 1 1 1 0 Centromere protein M (CENP-M) ATPase PF06745.13 EGR32473.1 - 0.03 13.7 2.4 2.7 7.3 0.0 2.4 1 1 0 2 2 2 0 KaiC LuxT_C PF18285.1 EGR32473.1 - 0.033 14.7 0.1 0.077 13.5 0.0 1.6 1 1 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain PduV-EutP PF10662.9 EGR32473.1 - 0.04 13.6 1.2 0.19 11.5 1.2 2.0 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.6 EGR32473.1 - 0.12 12.1 0.0 0.36 10.6 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EGR32473.1 - 0.18 12.2 0.0 0.27 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain MORN PF02493.20 EGR32474.1 - 2.5e-49 162.3 72.6 1.1e-07 31.3 0.6 10.4 11 0 0 11 11 11 9 MORN repeat PMR5N PF14416.6 EGR32474.1 - 4.9 7.6 10.0 9.7 6.6 0.8 3.9 4 0 0 4 4 4 0 PMR5 N terminal Domain zf-C3HC4_2 PF13923.6 EGR32475.1 - 3.9e-06 26.6 5.9 3.9e-06 26.6 5.9 3.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGR32475.1 - 7.1e-05 22.9 6.1 7.1e-05 22.9 6.1 3.1 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EGR32475.1 - 0.00039 20.4 5.1 0.00039 20.4 5.1 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGR32475.1 - 0.00046 20.0 6.2 0.00046 20.0 6.2 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGR32475.1 - 0.005 17.2 7.0 0.005 17.2 7.0 3.7 3 1 0 3 3 3 1 Ring finger domain zf-ACC PF17848.1 EGR32475.1 - 0.0056 16.7 2.1 0.0056 16.7 2.1 5.7 5 0 0 5 5 5 1 Acetyl-coA carboxylase zinc finger domain zf-TRAF PF02176.18 EGR32475.1 - 0.014 16.1 16.3 0.043 14.5 6.2 3.8 1 1 2 3 3 3 0 TRAF-type zinc finger SM-ATX PF14438.6 EGR32475.1 - 0.1 12.8 0.7 0.29 11.3 0.7 1.7 1 0 0 1 1 1 0 Ataxin 2 SM domain Gp138_N PF18352.1 EGR32475.1 - 0.11 12.6 0.2 0.32 11.1 0.2 1.7 1 0 0 1 1 1 0 Phage protein Gp138 N-terminal domain FlaC_arch PF05377.11 EGR32475.1 - 0.11 12.8 5.3 0.36 11.2 5.3 1.9 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) DUF1788 PF08747.11 EGR32475.1 - 0.39 10.7 5.2 0.092 12.8 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1788) Exonuc_VII_L PF02601.15 EGR32475.1 - 0.97 8.9 9.7 2.3 7.7 2.4 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit KTSC PF13619.6 EGR32476.1 - 0.068 13.0 0.1 4.8 7.1 0.0 2.5 2 1 1 3 3 3 0 KTSC domain DUF1065 PF06358.11 EGR32476.1 - 0.21 11.5 0.0 0.88 9.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1065) CCDC-167 PF15188.6 EGR32477.1 - 0.047 14.0 0.2 0.047 14.0 0.2 3.8 3 1 0 3 3 3 0 Coiled-coil domain-containing protein 167 RNA_helicase PF00910.22 EGR32477.1 - 1.3 9.4 7.6 0.89 10.0 4.7 2.3 2 0 0 2 2 2 0 RNA helicase DUF2079 PF09852.9 EGR32477.1 - 2.8 6.7 4.4 3.9 6.2 4.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2079) Ribosomal_L26 PF16906.5 EGR32478.1 - 2.3e-32 111.3 3.4 3.1e-32 110.9 3.4 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EGR32478.1 - 1.7e-08 34.1 2.9 1.7e-08 34.1 2.9 2.1 3 0 0 3 3 3 1 KOW motif DnaJ PF00226.31 EGR32479.1 - 5.5e-26 90.5 0.8 8.8e-26 89.8 0.8 1.3 1 0 0 1 1 1 1 DnaJ domain Fibrinogen_aC PF12160.8 EGR32479.1 - 0.0037 17.1 3.0 0.0073 16.1 3.0 1.5 1 0 0 1 1 1 1 Fibrinogen alpha C domain RPT PF13446.6 EGR32479.1 - 0.014 15.3 0.1 0.04 13.8 0.1 1.8 1 1 1 2 2 2 0 A repeated domain in UCH-protein Skp1 PF01466.19 EGR32480.1 - 5.7e-28 96.8 1.0 1.7e-27 95.3 1.0 1.9 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EGR32480.1 - 5.9e-25 87.2 2.5 1e-24 86.5 2.5 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 EGR32480.1 - 0.014 15.6 0.1 0.35 11.1 0.1 2.2 1 1 0 1 1 1 0 BTB/POZ domain MORN PF02493.20 EGR32483.1 - 8.7e-17 59.9 26.2 1.4e-07 30.9 3.6 5.0 5 0 0 5 5 5 4 MORN repeat Laminin_G_3 PF13385.6 EGR32484.1 - 1e-14 55.0 0.0 1.7e-14 54.3 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Thioredoxin PF00085.20 EGR32484.1 - 0.0065 16.4 0.1 0.016 15.2 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin Laminin_G_2 PF02210.24 EGR32484.1 - 0.07 13.7 0.0 0.42 11.2 0.0 2.1 1 1 0 1 1 1 0 Laminin G domain Laminin_G_1 PF00054.23 EGR32484.1 - 0.17 12.1 0.0 0.47 10.7 0.0 1.7 1 1 0 1 1 1 0 Laminin G domain Pyr_redox_2 PF07992.14 EGR32485.1 - 8.1e-13 48.3 0.0 8.7e-06 25.2 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGR32485.1 - 0.098 13.2 1.1 1 9.9 0.1 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pkinase PF00069.25 EGR32486.1 - 4.1e-33 114.9 2.1 4.9e-33 114.6 2.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32486.1 - 5.5e-19 68.5 0.3 6.7e-19 68.2 0.3 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DUF5128 PF17170.4 EGR32486.1 - 0.0067 15.6 1.1 0.0081 15.3 0.4 1.6 1 1 0 1 1 1 1 6-bladed beta-propeller Arm PF00514.23 EGR32487.1 - 0.00075 19.5 0.1 2.8 8.1 0.0 4.6 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 EGR32487.1 - 0.0012 19.4 15.1 0.021 15.4 0.7 5.8 5 1 1 6 6 6 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EGR32487.1 - 0.02 15.3 0.0 2.7 8.4 0.0 3.5 4 0 0 4 4 4 0 HEAT repeats RICTOR_V PF14668.6 EGR32487.1 - 0.029 14.6 1.2 0.98 9.7 0.3 3.5 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 Thr_synth_N PF14821.6 EGR32487.1 - 0.38 11.0 1.8 54 4.1 0.0 3.9 3 1 0 4 4 4 0 Threonine synthase N terminus eIF-1a PF01176.19 EGR32488.1 - 2.2e-18 65.8 0.1 4.4e-18 64.8 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Rtf2 PF04641.12 EGR32489.1 - 3.9e-63 213.3 14.7 4.6e-63 213.0 14.7 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger FYDLN_acid PF09538.10 EGR32489.1 - 0.008 16.9 6.3 0.094 13.4 7.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (FYDLN_acid) PIEZO PF15917.5 EGR32489.1 - 0.55 9.7 14.5 1.1 8.7 14.5 1.4 1 0 0 1 1 1 0 Piezo LMBR1 PF04791.16 EGR32489.1 - 1.3 7.8 3.7 1.4 7.8 3.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Ribosomal_S18 PF01084.20 EGR32490.1 - 2.3e-10 40.5 1.3 1e-09 38.4 0.3 2.7 2 0 0 2 2 2 1 Ribosomal protein S18 Nucleos_tra2_N PF01773.20 EGR32492.1 - 0.12 13.0 0.0 0.24 12.0 0.0 1.4 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter N-terminus PX PF00787.24 EGR32493.1 - 6.3e-20 71.3 4.1 6.3e-20 71.3 4.1 2.0 2 0 0 2 2 2 1 PX domain Trypan_glycop_C PF10659.9 EGR32493.1 - 1.8 9.0 8.2 0.12 12.8 2.9 1.7 2 0 0 2 2 2 0 Trypanosome variant surface glycoprotein C-terminal domain YokU PF14122.6 EGR32494.1 - 0.21 11.6 1.8 1.3 9.1 0.2 2.5 2 1 1 3 3 3 0 YokU-like protein, putative antitoxin Pkinase PF00069.25 EGR32495.1 - 2.5e-72 243.4 0.3 3.1e-72 243.1 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32495.1 - 1.3e-51 175.3 0.0 1.8e-51 175.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR32495.1 - 1.1e-08 34.3 0.0 3.2e-08 32.8 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGR32495.1 - 2.5e-07 30.3 0.1 1.9e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGR32495.1 - 0.00012 21.1 1.0 0.0002 20.4 1.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EGR32495.1 - 0.00058 19.5 0.7 0.75 9.4 0.2 2.3 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGR32495.1 - 0.0086 15.4 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EGR32495.1 - 0.017 14.7 0.4 0.042 13.4 0.3 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL GBP PF02263.19 EGR32496.1 - 4.2e-58 196.6 6.7 4.2e-58 196.6 6.7 1.9 3 0 0 3 3 3 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 EGR32496.1 - 0.00074 19.6 0.0 0.0027 17.8 0.0 2.1 1 1 1 2 2 2 1 50S ribosome-binding GTPase MFS_2 PF13347.6 EGR32497.1 - 1.6e-26 92.8 28.7 5.1e-23 81.3 5.5 2.7 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1 PF07690.16 EGR32497.1 - 6.4e-20 71.4 12.7 9e-13 47.9 0.0 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4838 PF16126.5 EGR32497.1 - 0.032 13.6 0.1 0.067 12.5 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4838) DUF3611 PF12263.8 EGR32497.1 - 0.05 13.5 8.7 0.31 10.9 0.1 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3611) DUF3043 PF11241.8 EGR32497.1 - 4.1 7.4 4.9 0.74 9.8 0.2 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3043) Kelch_6 PF13964.6 EGR32498.1 - 1.9e-16 59.7 1.7 8.6e-06 25.9 0.0 3.7 3 1 1 4 4 4 3 Kelch motif Kelch_4 PF13418.6 EGR32498.1 - 3.6e-16 58.9 0.7 1.1e-05 25.3 0.0 3.2 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_1 PF01344.25 EGR32498.1 - 7.1e-16 57.5 1.2 2e-07 30.4 0.0 4.4 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 EGR32498.1 - 1.1e-07 31.7 6.3 9.9e-05 22.2 0.0 3.4 4 1 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 EGR32498.1 - 3e-07 30.1 1.3 0.087 12.8 0.0 3.9 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 EGR32498.1 - 6e-06 26.4 0.8 0.0068 16.7 0.0 3.4 4 1 0 4 4 4 2 Galactose oxidase, central domain RAG2 PF03089.14 EGR32498.1 - 0.00039 19.5 0.1 0.12 11.3 0.0 2.3 2 1 0 2 2 2 2 Recombination activating protein 2 HSP70 PF00012.20 EGR32499.1 - 9.1e-163 542.6 1.1 1.1e-162 542.4 1.1 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGR32499.1 - 7e-16 57.9 0.6 6.1e-13 48.3 0.1 2.4 2 1 0 2 2 2 2 MreB/Mbl protein BcrAD_BadFG PF01869.20 EGR32499.1 - 0.16 11.5 0.0 2 7.8 0.0 2.2 1 1 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Usp PF00582.26 EGR32500.1 - 5.1e-13 49.7 0.0 2.1e-06 28.3 0.0 3.1 3 0 0 3 3 3 3 Universal stress protein family PNK3P PF08645.11 EGR32500.1 - 0.83 9.3 4.9 2.8 7.6 0.4 2.5 2 1 0 2 2 2 0 Polynucleotide kinase 3 phosphatase DJ-1_PfpI PF01965.24 EGR32501.1 - 1.7e-06 28.0 0.1 7.9e-06 25.8 0.1 1.9 1 1 0 1 1 1 1 DJ-1/PfpI family MORN PF02493.20 EGR32502.1 - 4e-32 108.2 87.0 9.8e-05 22.0 4.4 10.8 11 0 0 11 11 11 10 MORN repeat MORN_2 PF07661.13 EGR32502.1 - 2.8e-07 30.0 68.2 0.1 12.9 0.6 10.6 11 0 0 11 11 11 8 MORN repeat variant Ephrin_rec_like PF07699.13 EGR32503.1 - 3.4e-09 36.3 40.5 0.00099 18.8 0.5 6.8 4 3 4 8 8 8 4 Putative ephrin-receptor like Antistasin PF02822.14 EGR32503.1 - 7.1e-05 23.4 3.7 2.2 9.0 0.1 5.2 5 0 0 5 5 5 2 Antistasin family NCD3G PF07562.14 EGR32503.1 - 0.077 13.0 36.1 1.9 8.5 5.0 6.2 4 3 0 4 4 4 0 Nine Cysteines Domain of family 3 GPCR Kinesin PF00225.23 EGR32504.1 - 1.3e-102 343.1 5.0 1.3e-102 343.1 5.0 4.3 4 1 0 5 5 5 1 Kinesin motor domain Microtub_bd PF16796.5 EGR32504.1 - 5.1e-24 84.9 0.3 5.1e-24 84.9 0.3 5.1 4 2 1 5 5 5 1 Microtubule binding HutP PF09021.11 EGR32504.1 - 4.3 7.6 8.2 0.77 10.1 1.9 2.8 2 0 0 2 2 2 0 HutP Roc PF08477.13 EGR32505.1 - 3.5e-13 49.8 0.0 6.7e-13 48.9 0.0 1.4 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGR32505.1 - 5.2e-11 42.4 0.0 5.9e-11 42.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGR32505.1 - 0.00011 21.6 0.0 0.0065 15.8 0.0 2.3 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EGR32505.1 - 0.00022 20.7 0.0 0.00034 20.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR32505.1 - 0.002 18.2 0.0 0.0028 17.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGR32505.1 - 0.0069 15.9 0.0 0.16 11.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EGR32505.1 - 0.02 14.0 0.0 0.97 8.5 0.0 2.2 1 1 1 2 2 2 0 G-protein alpha subunit Dynamin_N PF00350.23 EGR32505.1 - 0.096 12.7 0.1 0.1 12.7 0.1 1.4 1 1 0 1 1 1 0 Dynamin family AAA_18 PF13238.6 EGR32505.1 - 0.13 12.9 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain PMSR PF01625.21 EGR32507.1 - 1.9e-61 206.7 5.5 2.2e-61 206.5 5.5 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase DUF4298 PF14131.6 EGR32507.1 - 0.46 10.5 7.8 0.3 11.1 5.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4298) Peptidase_M8 PF01457.16 EGR32509.1 - 1.6e-30 106.3 0.1 3.3e-27 95.4 0.1 2.0 1 1 1 2 2 2 2 Leishmanolysin zf-ANAPC11 PF12861.7 EGR32509.1 - 0.014 15.5 0.3 0.56 10.3 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Astacin PF01400.24 EGR32509.1 - 0.065 12.8 1.0 0.38 10.3 0.0 2.1 2 0 0 2 2 2 0 Astacin (Peptidase family M12A) PA26 PF04636.13 EGR32510.1 - 1.5e-32 113.2 0.4 4.5e-32 111.5 0.0 1.8 2 0 0 2 2 2 1 PA26 p53-induced protein (sestrin) DUF3135 PF11333.8 EGR32510.1 - 0.073 13.3 1.2 0.16 12.2 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) DUF468 PF04318.12 EGR32510.1 - 0.12 13.1 1.8 2.6 8.8 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF468) Pkinase PF00069.25 EGR32511.1 - 5.5e-22 78.4 0.0 5.9e-22 78.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32511.1 - 3.9e-21 75.5 0.0 4.3e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 EGR32512.1 - 0.00076 20.2 0.0 0.042 14.7 0.0 2.9 3 0 0 3 3 3 1 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EGR32512.1 - 0.0033 16.4 1.3 0.0069 15.4 0.3 1.8 2 0 0 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein NAD1 PF18778.1 EGR32512.1 - 0.0034 17.5 0.3 0.0071 16.4 0.3 1.5 1 0 0 1 1 1 1 Novel AID APOBEC clade 1 APOBEC3 PF18771.1 EGR32512.1 - 0.023 14.8 0.3 0.051 13.7 0.3 1.6 1 0 0 1 1 1 0 APOBEC3 Nup160 PF11715.8 EGR32512.1 - 0.027 13.1 0.1 0.05 12.2 0.1 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGR32512.1 - 0.056 13.7 0.3 3.5 8.0 0.1 2.8 1 1 3 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DEAD_2 PF06733.15 EGR32513.1 - 4.9e-45 153.3 8.4 1.1e-44 152.1 8.4 1.7 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 EGR32513.1 - 7e-41 140.2 0.1 7e-41 140.2 0.1 2.6 3 0 0 3 3 3 1 Helicase C-terminal domain HBB PF06777.11 EGR32513.1 - 7.9e-18 64.8 4.8 1.1e-13 51.2 2.2 3.0 2 1 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 EGR32513.1 - 1.9e-07 31.2 6.8 1.9e-07 31.2 6.8 3.2 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGR32513.1 - 0.00014 21.7 0.7 0.022 14.6 0.1 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGR32513.1 - 0.016 15.5 0.4 2.2 8.6 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 EGR32513.1 - 0.58 10.5 2.6 0.63 10.4 0.2 2.3 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EGR32513.1 - 0.94 9.2 10.6 0.022 14.5 1.2 2.5 2 1 0 2 2 2 0 AAA domain PRP1_N PF06424.12 EGR32513.1 - 6.7 7.1 10.1 0.4 11.1 4.3 2.0 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal Pkinase PF00069.25 EGR32514.1 - 2.7e-54 184.3 1.9 2.7e-54 184.3 1.9 1.8 1 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32514.1 - 2.1e-40 138.6 0.6 2.1e-40 138.6 0.6 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR32514.1 - 1.4e-05 24.1 0.5 3e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 EGR32514.1 - 0.0093 15.6 1.6 0.0093 15.6 1.6 1.9 2 1 0 2 2 2 1 RIO1 family DUF1512 PF07431.12 EGR32514.1 - 0.84 8.6 5.5 0.75 8.7 4.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1512) Ion_trans_2 PF07885.16 EGR32515.1 - 6.9e-12 45.2 8.1 6.9e-12 45.2 8.1 3.1 2 2 0 2 2 2 1 Ion channel Ion_trans PF00520.31 EGR32515.1 - 0.73 9.0 59.4 44 3.2 59.4 2.7 1 1 0 1 1 1 0 Ion transport protein WD40 PF00400.32 EGR32517.1 - 1e-07 32.5 0.7 0.64 11.0 0.0 4.9 4 1 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR32517.1 - 5.5e-06 26.6 0.4 0.008 16.5 0.2 3.2 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Sin3_corepress PF08295.12 EGR32517.1 - 0.37 10.9 6.5 0.047 13.8 1.6 2.1 3 0 0 3 3 3 0 Sin3 family co-repressor CotJB PF12652.7 EGR32519.1 - 0.74 10.1 0.0 0.74 10.1 0.0 3.2 4 0 0 4 4 4 0 CotJB protein eIF-5_eIF-2B PF01873.17 EGR32519.1 - 1.8 8.4 4.6 4.3 7.2 0.1 3.1 3 1 0 3 3 3 0 Domain found in IF2B/IF5 WD40 PF00400.32 EGR32520.1 - 1e-18 67.3 15.5 4.8e-05 24.0 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR32520.1 - 2.4e-14 53.4 1.3 9.1e-07 29.1 0.0 5.1 1 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGR32520.1 - 0.0002 20.8 3.3 0.13 11.6 0.0 3.9 3 1 0 3 3 3 1 WD40-like domain BBS2_Mid PF14783.6 EGR32520.1 - 0.062 13.3 1.2 11 6.1 0.0 3.7 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region DUF4784 PF16023.5 EGR32520.1 - 0.08 11.9 0.0 0.22 10.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4784) Ge1_WD40 PF16529.5 EGR32520.1 - 0.25 10.3 2.7 2.4 7.0 0.1 2.9 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Kinesin PF00225.23 EGR32522.1 - 1e-97 327.1 4.9 1.9e-97 326.2 4.9 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR32522.1 - 2.7e-18 66.4 2.2 2.7e-18 66.4 2.2 2.2 2 1 0 2 2 2 1 Microtubule binding DUF150_C PF17384.2 EGR32522.1 - 0.083 13.0 0.5 5 7.3 0.2 2.6 2 0 0 2 2 2 0 RimP C-terminal SH3 domain DUF4482 PF14818.6 EGR32522.1 - 1.3 9.9 10.0 3.2 8.6 4.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4482) Terminase_2 PF03592.16 EGR32522.1 - 2.3 8.7 7.6 0.76 10.2 3.4 2.4 2 0 0 2 2 2 0 Terminase small subunit MutS_III PF05192.18 EGR32522.1 - 4.3 7.5 6.7 39 4.4 6.6 2.3 1 1 0 1 1 1 0 MutS domain III ATP-cone PF03477.16 EGR32522.1 - 9.4 6.9 12.1 1.9 9.1 3.1 3.6 3 1 0 3 3 3 0 ATP cone domain SMC_N PF02463.19 EGR32524.1 - 3.7e-16 59.2 0.1 4.3e-16 59.0 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGR32524.1 - 4e-05 23.6 0.0 4.6e-05 23.4 0.0 1.2 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EGR32524.1 - 0.071 13.3 0.0 0.13 12.5 0.0 1.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 EGR32526.1 - 5.2e-27 94.7 0.0 6.9e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGR32526.1 - 0.00015 21.6 0.3 0.00027 20.8 0.1 1.5 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran PF00005.27 EGR32526.1 - 0.063 13.8 0.0 0.11 13.0 0.0 1.5 1 0 0 1 1 1 0 ABC transporter DUF4572 PF15139.6 EGR32527.1 - 0.0064 16.4 0.5 0.0064 16.4 0.5 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4572) DUF5530 PF17670.1 EGR32527.1 - 0.015 15.1 2.5 0.035 13.9 0.5 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5530) Swm2 PF17083.5 EGR32527.1 - 0.017 15.2 0.6 0.017 15.2 0.6 2.0 1 1 1 2 2 2 0 Nucleolar protein Swm2 Ribosomal_L12 PF00542.19 EGR32528.1 - 7.1e-21 74.3 6.7 1.5e-20 73.3 6.7 1.6 1 0 0 1 1 1 1 Ribosomal protein L7/L12 C-terminal domain Spt20 PF12090.8 EGR32528.1 - 0.067 12.8 1.0 0.095 12.3 1.0 1.3 1 0 0 1 1 1 0 Spt20 family DUF3072 PF11272.8 EGR32528.1 - 1.4 8.8 5.1 3.4 7.6 0.3 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3072) Ctf8 PF09696.10 EGR32529.1 - 0.039 14.3 0.5 11 6.3 0.1 2.3 1 1 2 3 3 3 0 Ctf8 SopD PF11047.8 EGR32529.1 - 0.078 12.2 0.0 0.085 12.0 0.0 1.0 1 0 0 1 1 1 0 Salmonella outer protein D ABC_tran PF00005.27 EGR32530.1 - 1.8e-47 161.3 1.9 2e-22 80.2 0.2 2.9 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EGR32530.1 - 6.3e-23 80.6 1.7 6.3e-23 80.6 1.7 3.3 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 EGR32530.1 - 4e-21 76.1 10.5 7.4e-07 29.3 0.1 4.7 4 1 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGR32530.1 - 2.5e-11 43.5 3.3 0.00047 19.7 0.0 3.9 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGR32530.1 - 6.7e-10 39.2 0.0 0.00026 20.8 0.0 3.3 2 1 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EGR32530.1 - 2.8e-07 30.9 1.3 0.00017 21.9 0.0 3.4 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGR32530.1 - 8.8e-07 28.6 0.2 0.0055 16.4 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGR32530.1 - 2e-06 27.8 0.2 0.038 13.9 0.1 2.6 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGR32530.1 - 3.3e-06 27.2 0.5 0.077 13.1 0.0 3.3 3 1 1 4 4 3 2 50S ribosome-binding GTPase AAA_18 PF13238.6 EGR32530.1 - 8.5e-06 26.3 0.3 0.84 10.2 0.0 4.2 4 0 0 4 4 4 1 AAA domain Roc PF08477.13 EGR32530.1 - 1.4e-05 25.3 0.0 0.11 12.7 0.0 2.9 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 EGR32530.1 - 5.1e-05 23.9 16.0 0.0052 17.3 0.0 4.4 3 1 1 4 4 3 2 AAA domain AAA_16 PF13191.6 EGR32530.1 - 0.00016 22.1 0.9 0.68 10.3 0.0 2.7 2 1 0 2 2 2 2 AAA ATPase domain AAA_24 PF13479.6 EGR32530.1 - 0.00018 21.3 0.0 0.18 11.5 0.0 2.9 2 0 0 2 2 2 1 AAA domain NICE-3 PF07406.11 EGR32530.1 - 0.0003 20.8 0.4 0.0039 17.2 0.2 2.3 2 0 0 2 2 2 1 NICE-3 protein AAA_28 PF13521.6 EGR32530.1 - 0.0004 20.7 0.0 0.72 10.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain Ras PF00071.22 EGR32530.1 - 0.00086 18.9 0.1 0.3 10.7 0.0 2.5 2 0 0 2 2 2 1 Ras family NACHT PF05729.12 EGR32530.1 - 0.00086 19.3 0.3 0.8 9.6 0.0 2.8 3 0 0 3 3 2 1 NACHT domain AAA_27 PF13514.6 EGR32530.1 - 0.0029 17.2 2.4 0.11 12.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 EGR32530.1 - 0.003 18.0 0.2 0.62 10.5 0.1 3.1 2 2 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SbcCD_C PF13558.6 EGR32530.1 - 0.004 17.3 0.3 0.18 12.0 0.1 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit PRK PF00485.18 EGR32530.1 - 0.0042 16.8 0.3 1 9.1 0.0 2.5 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 EGR32530.1 - 0.0044 16.6 0.7 1.6 8.3 0.0 3.6 4 0 0 4 4 4 1 AAA domain Dynamin_N PF00350.23 EGR32530.1 - 0.0058 16.7 3.1 0.41 10.7 0.0 3.4 3 1 0 3 3 2 1 Dynamin family RNA_helicase PF00910.22 EGR32530.1 - 0.0085 16.5 0.0 2.6 8.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 EGR32530.1 - 0.022 14.2 0.0 4.4 6.8 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 EGR32530.1 - 0.026 14.5 0.1 0.97 9.4 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EGR32530.1 - 0.035 14.3 0.2 8.2 6.6 0.0 3.1 2 1 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EGR32530.1 - 0.049 13.4 0.1 10 5.8 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 EGR32530.1 - 0.077 12.7 0.0 7.4 6.2 0.0 2.9 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.18 EGR32530.1 - 0.092 12.1 0.0 0.41 10.0 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family FeoB_N PF02421.18 EGR32530.1 - 0.13 11.7 0.1 15 5.1 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B Com_YlbF PF06133.11 EGR32530.1 - 4.2 8.0 11.9 0.35 11.5 3.4 2.5 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Ifi-6-16 PF06140.13 EGR32531.1 - 7.7e-20 70.6 25.1 9.8e-20 70.3 25.1 1.1 1 0 0 1 1 1 1 Interferon-induced 6-16 family RcpC PF16976.5 EGR32531.1 - 0.15 12.1 0.7 13 5.9 0.1 2.1 2 0 0 2 2 2 0 Flp pilus assembly protein RcpC/CpaB Pik1 PF11522.8 EGR32532.1 - 4.9 7.2 9.3 0.15 12.0 1.5 2.5 3 0 0 3 3 3 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Popeye PF04831.13 EGR32532.1 - 8 6.6 9.9 13 5.9 9.9 1.3 1 0 0 1 1 1 0 Popeye protein conserved region Ion_trans_2 PF07885.16 EGR32533.1 - 6.1e-08 32.5 0.1 7.1e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGR32533.1 - 0.022 14.0 0.1 0.026 13.8 0.1 1.1 1 0 0 1 1 1 0 Ion transport protein Abhydrolase_3 PF07859.13 EGR32534.1 - 2.3e-43 148.5 0.0 2e-42 145.5 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGR32534.1 - 1e-10 41.0 5.6 1e-10 41.0 5.6 1.8 2 1 0 3 3 3 1 Steryl acetyl hydrolase COesterase PF00135.28 EGR32534.1 - 0.0047 15.9 0.1 0.04 12.8 0.0 2.2 1 1 0 1 1 1 1 Carboxylesterase family HSP90 PF00183.18 EGR32535.1 - 1.1e-140 469.9 43.9 1.8e-140 469.3 43.9 1.3 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.6 EGR32535.1 - 5.2e-12 45.8 0.3 5.2e-12 45.8 0.3 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGR32535.1 - 3.4e-11 43.6 0.2 8e-11 42.4 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HU-CCDC81_bac_1 PF18174.1 EGR32535.1 - 0.12 12.3 0.0 0.4 10.6 0.0 1.9 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 1 DUF4530 PF15039.6 EGR32536.1 - 6.7 6.9 6.4 0.89 9.7 1.1 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4530) RabGAP-TBC PF00566.18 EGR32537.1 - 7.6e-36 123.8 28.7 2.8e-33 115.4 12.3 3.0 1 1 1 2 2 2 2 Rab-GTPase-TBC domain DUF3385 PF11865.8 EGR32537.1 - 0.015 15.3 1.3 0.03 14.2 0.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3385) Ion_trans PF00520.31 EGR32538.1 - 6.7e-198 654.3 142.5 4.1e-56 190.0 24.0 4.9 5 0 0 5 5 5 4 Ion transport protein PKD_channel PF08016.12 EGR32538.1 - 7.1e-13 48.0 109.2 3.3e-06 26.0 18.6 9.9 5 4 4 9 9 9 8 Polycystin cation channel EF-hand_6 PF13405.6 EGR32539.1 - 3.3e-36 120.1 29.8 3.1e-05 23.6 0.5 9.5 9 0 0 9 9 9 7 EF-hand domain EF-hand_1 PF00036.32 EGR32539.1 - 2.3e-35 117.5 34.1 1e-06 27.9 0.3 9.7 10 0 0 10 10 10 8 EF hand EF-hand_7 PF13499.6 EGR32539.1 - 4.1e-32 110.4 32.1 2.9e-10 40.5 4.4 6.2 4 1 2 6 6 6 6 EF-hand domain pair EF-hand_8 PF13833.6 EGR32539.1 - 6e-18 64.4 24.4 1.9e-08 34.0 0.2 7.3 7 1 1 8 8 8 3 EF-hand domain pair EF-hand_5 PF13202.6 EGR32539.1 - 6e-16 57.1 26.0 0.0013 18.1 0.2 8.5 8 0 0 8 8 8 5 EF hand UCH PF00443.29 EGR32539.1 - 8.8e-15 54.9 29.7 8.8e-15 54.9 29.7 3.5 2 2 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase EF-hand_4 PF12763.7 EGR32539.1 - 0.00067 19.6 3.6 1.2 9.1 0.1 4.0 3 0 0 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 EGR32539.1 - 0.0042 17.9 5.1 0.17 12.8 0.1 4.3 4 1 1 5 5 5 1 EF-hand domain PilN_bio_d PF18222.1 EGR32539.1 - 0.075 13.4 0.8 0.88 10.0 0.0 3.1 3 0 0 3 3 3 0 PilN biogenesis protein dimerization domain EF-hand_10 PF14788.6 EGR32539.1 - 0.35 10.8 7.5 24 4.9 0.2 4.8 4 1 1 5 5 5 0 EF hand MORN PF02493.20 EGR32540.1 - 1.9e-25 87.2 31.2 3.9e-08 32.7 0.9 5.5 5 0 0 5 5 5 4 MORN repeat Methyltr_RsmB-F PF01189.17 EGR32540.1 - 0.025 14.2 0.0 0.046 13.4 0.0 1.4 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F DSHCT PF08148.12 EGR32541.1 - 1.2e-37 129.1 0.8 4.9e-37 127.1 0.1 2.6 2 0 0 2 2 2 1 DSHCT (NUC185) domain DEAD PF00270.29 EGR32541.1 - 2.3e-17 63.3 0.3 1.1e-16 61.1 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR32541.1 - 8e-05 22.9 0.8 8e-05 22.9 0.8 4.8 4 1 0 4 4 4 1 Helicase conserved C-terminal domain SoxY PF13501.6 EGR32541.1 - 0.082 13.1 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Sulfur oxidation protein SoxY Cbl_N2 PF02761.14 EGR32541.1 - 4.9 7.9 7.3 1.4 9.6 1.0 3.6 3 0 0 3 3 3 0 CBL proto-oncogene N-terminus, EF hand-like domain Lyase_1 PF00206.20 EGR32542.1 - 5.8e-111 370.8 0.0 7.2e-111 370.5 0.0 1.1 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EGR32542.1 - 3.6e-23 81.7 0.8 1.4e-22 79.8 0.0 2.4 3 0 0 3 3 3 1 Fumarase C C-terminus Peptidase_M8 PF01457.16 EGR32543.1 - 1.7e-31 109.6 11.1 2.3e-11 43.1 0.3 3.1 2 1 1 3 3 3 3 Leishmanolysin EGF_Tenascin PF18720.1 EGR32543.1 - 3.2e-08 33.4 9.7 3.2e-08 33.4 9.7 2.8 3 0 0 3 3 3 1 Tenascin EGF domain EGF_2 PF07974.13 EGR32543.1 - 0.0053 17.1 13.0 0.0053 17.1 13.0 3.5 3 0 0 3 3 3 1 EGF-like domain RIH_assoc PF08454.11 EGR32545.1 - 4.9e-18 64.9 7.6 4.9e-18 64.9 7.6 7.6 4 2 3 7 7 7 1 RyR and IP3R Homology associated Ion_trans PF00520.31 EGR32545.1 - 3.4e-09 36.3 27.9 8.9e-09 34.9 27.9 1.8 1 0 0 1 1 1 1 Ion transport protein UPF0051 PF01458.17 EGR32546.1 - 0.17 11.6 6.9 9.1 5.9 0.6 4.1 4 0 0 4 4 4 0 Uncharacterized protein family (UPF0051) E1-E2_ATPase PF00122.20 EGR32547.1 - 6.2e-07 29.1 0.1 8.4e-07 28.7 0.1 1.1 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EGR32547.1 - 0.0046 17.3 0.0 0.0055 17.0 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGR32548.1 - 8.4e-07 29.5 0.0 0.0018 18.6 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase UQ_con PF00179.26 EGR32549.1 - 9.7e-35 119.3 0.3 1.6e-34 118.6 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGR32549.1 - 0.0023 17.6 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B Ribosomal_L2_C PF03947.18 EGR32550.1 - 6e-48 162.2 3.7 9.5e-48 161.6 3.7 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EGR32550.1 - 5.8e-12 45.4 1.2 1.2e-11 44.4 0.5 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain PhoLip_ATPase_C PF16212.5 EGR32551.1 - 6.1e-47 160.5 36.2 6.1e-47 160.5 36.2 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EGR32551.1 - 3.3e-12 47.2 0.1 2e-08 34.8 0.1 2.8 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGR32551.1 - 3.5e-12 46.2 0.1 8.8e-11 41.7 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGR32551.1 - 0.006 16.3 2.7 0.032 13.9 0.1 3.1 1 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase dCache_3 PF14827.6 EGR32551.1 - 0.19 11.3 1.4 8.8 5.9 0.2 2.8 3 0 0 3 3 3 0 Double sensory domain of two-component sensor kinase TAF PF02969.17 EGR32551.1 - 0.2 11.9 0.7 0.72 10.1 0.2 2.1 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) Histone PF00125.24 EGR32552.1 - 4.5e-15 56.2 1.5 5.9e-15 55.8 1.5 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGR32552.1 - 1.4e-05 25.3 0.1 2.3e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGR32552.1 - 0.058 13.9 0.1 0.091 13.3 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A AD PF09793.9 EGR32552.1 - 0.063 13.4 0.4 0.11 12.6 0.4 1.4 1 0 0 1 1 1 0 Anticodon-binding domain HSCB_C PF07743.13 EGR32553.1 - 7.3e-17 61.6 12.9 2.4e-16 60.0 5.3 2.7 2 1 0 2 2 2 2 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EGR32553.1 - 1.3e-05 25.2 3.8 1.3e-05 25.2 3.8 2.3 2 0 0 2 2 2 1 DnaJ domain Mit_KHE1 PF10173.9 EGR32553.1 - 0.52 10.4 7.2 1.8 8.6 1.2 2.1 1 1 1 2 2 2 0 Mitochondrial K+-H+ exchange-related RNase_HII PF01351.18 EGR32553.1 - 1.5 8.6 7.1 0.38 10.6 4.1 1.4 2 0 0 2 2 2 0 Ribonuclease HII DUF4041 PF13250.6 EGR32553.1 - 6.6 6.7 11.7 2.9 7.8 0.6 4.0 4 1 0 4 4 4 0 Domain of unknown function (DUF4041) ERCC3_RAD25_C PF16203.5 EGR32554.1 - 1.7e-72 243.6 3.0 4.4e-72 242.3 3.0 1.7 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 EGR32554.1 - 1.7e-23 83.4 1.2 1.7e-23 83.4 1.2 2.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C_3 PF13625.6 EGR32554.1 - 3.8e-20 72.3 0.0 6.4e-20 71.6 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EGR32554.1 - 1.9e-13 49.9 0.4 3.1e-13 49.2 0.4 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGR32554.1 - 4.7e-11 43.0 0.4 4.7e-11 43.0 0.4 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGR32554.1 - 0.0021 18.3 0.0 0.0063 16.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_34 PF13872.6 EGR32554.1 - 0.0025 16.8 0.3 0.0047 15.9 0.3 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 JIP_LZII PF16471.5 EGR32554.1 - 0.0028 17.8 0.3 0.013 15.7 0.1 2.2 2 0 0 2 2 2 1 JNK-interacting protein leucine zipper II DEAD PF00270.29 EGR32554.1 - 0.0036 17.1 1.5 0.013 15.3 0.1 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase Ehbp PF10622.9 EGR32554.1 - 0.074 13.1 0.6 7.7 6.6 0.1 3.3 3 0 0 3 3 3 0 Energy-converting hydrogenase B subunit P (EhbP) WD40 PF00400.32 EGR32555.1 - 2.1e-24 85.3 5.4 5.9e-07 30.1 0.0 4.4 4 1 0 4 4 4 4 WD domain, G-beta repeat WD40_like PF17005.5 EGR32555.1 - 5.2e-05 22.7 0.4 0.00019 20.9 0.4 1.6 1 1 0 1 1 1 1 WD40-like domain Ge1_WD40 PF16529.5 EGR32555.1 - 0.00011 21.3 1.5 0.0003 19.9 1.5 1.8 1 1 0 1 1 1 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGR32555.1 - 0.00089 18.0 0.9 0.41 9.2 0.1 3.0 1 1 2 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGR32555.1 - 0.00092 19.5 0.1 0.5 10.7 0.1 2.6 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ca_hom_mod PF14798.6 EGR32556.1 - 0.0026 16.9 1.6 0.0029 16.7 1.6 1.2 1 0 0 1 1 1 1 Calcium homeostasis modulator DUF1461 PF07314.11 EGR32556.1 - 0.045 13.7 5.0 0.057 13.3 5.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) SNARE PF05739.19 EGR32556.1 - 1.5 8.8 8.4 0.64 10.1 2.5 2.4 2 0 0 2 2 2 0 SNARE domain Peroxin-13_N PF04088.13 EGR32556.1 - 1.6 9.0 7.2 2.2 8.6 0.1 2.5 2 1 1 3 3 3 0 Peroxin 13, N-terminal region SF-assemblin PF06705.11 EGR32557.1 - 1.6e-09 37.5 30.3 4.2e-08 32.8 9.3 2.2 1 1 1 2 2 2 2 SF-assemblin/beta giardin DUF2385 PF09539.10 EGR32557.1 - 0.026 15.1 0.6 0.075 13.6 0.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2385) MatP_C PF17414.2 EGR32557.1 - 0.033 14.4 0.3 0.033 14.4 0.3 2.5 3 0 0 3 3 3 0 MatP C-terminal ribbon-helix-helix domain LPP PF04728.13 EGR32557.1 - 0.4 11.1 7.4 0.54 10.7 3.3 3.1 2 1 0 2 2 2 0 Lipoprotein leucine-zipper TraF_2 PF13729.6 EGR32557.1 - 1 8.7 4.2 0.32 10.3 0.4 1.9 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein ApoO PF09769.9 EGR32557.1 - 2.2 8.2 3.9 1.8 8.5 1.1 2.2 1 1 2 3 3 3 0 Apolipoprotein O NPV_P10 PF05531.12 EGR32557.1 - 2.2 8.8 18.3 2.1 8.8 1.1 4.2 3 1 1 4 4 4 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 EGR32557.1 - 3.9 7.5 11.6 9.4 6.3 0.7 3.2 2 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF948 PF06103.11 EGR32557.1 - 5.8 7.2 7.7 14 6.0 0.2 2.9 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) VlpA_repeat PF04649.12 EGR32557.1 - 7.5 7.0 6.5 46 4.6 0.3 3.2 3 0 0 3 3 3 0 Mycoplasma hyorhinis VlpA repeat TPK_B1_binding PF04265.14 EGR32558.1 - 3e-13 49.3 0.1 3.8e-13 48.9 0.1 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain XRN_N PF03159.18 EGR32559.1 - 7.7e-85 284.2 0.1 7.7e-85 284.2 0.1 2.3 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 EGR32559.1 - 4.6e-63 213.7 14.5 4.6e-63 213.7 14.5 2.1 2 0 0 2 2 2 1 Xrn1 helical domain SH3_12 PF18129.1 EGR32559.1 - 3e-17 62.5 0.1 5.7e-17 61.6 0.1 1.5 1 0 0 1 1 1 1 Xrn1 SH3-like domain Lipase_GDSL PF00657.22 EGR32559.1 - 0.016 15.2 6.9 0.048 13.6 6.9 1.9 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase U1snRNP70_N PF12220.8 EGR32559.1 - 0.57 10.9 0.0 0.57 10.9 0.0 3.0 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Paf67 PF10255.9 EGR32561.1 - 5.3e-24 85.0 8.1 6.4e-24 84.7 8.1 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 TcdB_N PF12918.7 EGR32561.1 - 0.032 14.5 3.2 0.032 14.5 3.2 2.6 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain PCI PF01399.27 EGR32561.1 - 0.038 14.5 2.0 0.098 13.2 2.0 2.0 1 1 0 1 1 1 0 PCI domain adh_short PF00106.25 EGR32563.1 - 3.5e-14 52.7 0.0 2.7e-13 49.8 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGR32563.1 - 1e-06 28.5 0.0 4.3e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Actin PF00022.19 EGR32566.1 - 3.4e-54 184.0 0.0 1.3e-52 178.8 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGR32566.1 - 0.045 12.6 0.0 1.5 7.6 0.0 2.1 2 0 0 2 2 2 0 MreB/Mbl protein Hydrolase_like PF13242.6 EGR32567.1 - 3.5e-20 71.8 0.0 5.8e-20 71.1 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 EGR32567.1 - 2.4e-11 43.7 0.1 7.2e-11 42.1 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EGR32567.1 - 0.018 14.7 0.1 0.2 11.3 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial PGP phosphatase Ilm1 PF10311.9 EGR32567.1 - 0.049 13.3 0.0 0.085 12.5 0.0 1.3 1 0 0 1 1 1 0 Increased loss of mitochondrial DNA protein 1 MFS_1 PF07690.16 EGR32568.1 - 2.5e-32 112.2 32.0 2.4e-21 76.0 12.8 2.7 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EGR32568.1 - 4.7e-10 38.9 26.3 7e-08 31.7 23.2 3.2 2 1 0 2 2 2 2 MFS_1 like family Sugar_tr PF00083.24 EGR32568.1 - 0.00012 21.1 32.0 0.013 14.4 12.6 3.2 1 1 1 3 3 3 3 Sugar (and other) transporter MLANA PF14991.6 EGR32568.1 - 0.047 14.0 0.2 0.12 12.7 0.2 1.7 1 0 0 1 1 1 0 Protein melan-A MFS_4 PF06779.14 EGR32568.1 - 2.5 7.3 16.8 0.022 14.1 6.9 2.3 3 0 0 3 3 3 0 Uncharacterised MFS-type transporter YbfB cNMP_binding PF00027.29 EGR32569.1 - 1.5e-15 57.0 0.0 2.6e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGR32569.1 - 3.5e-10 39.7 10.0 3.5e-10 39.7 10.0 2.5 2 1 0 2 2 2 1 Ion channel UN_NPL4 PF11543.8 EGR32569.1 - 0.049 14.1 0.9 9.6 6.8 0.1 2.6 2 0 0 2 2 2 0 Nuclear pore localisation protein NPL4 dUTPase_2 PF08761.11 EGR32570.1 - 0.011 16.0 2.9 0.011 15.9 2.9 1.0 1 0 0 1 1 1 0 dUTPase DER1 PF04511.15 EGR32571.1 - 6e-31 107.9 18.4 8.1e-31 107.4 18.4 1.2 1 0 0 1 1 1 1 Der1-like family GMP_PDE_delta PF05351.11 EGR32572.1 - 0.064 13.3 7.3 0.23 11.5 0.0 3.1 2 1 1 3 3 3 0 GMP-PDE, delta subunit NOD2_WH PF17779.1 EGR32572.1 - 0.097 13.0 0.2 1.1 9.7 0.1 2.5 2 0 0 2 2 2 0 NOD2 winged helix domain Acetone_carb_G PF08882.11 EGR32573.1 - 0.027 14.6 0.9 0.027 14.6 0.9 1.6 2 0 0 2 2 2 0 Acetone carboxylase gamma subunit NAD_binding_5 PF07994.12 EGR32574.1 - 1.9 7.8 7.4 8 5.7 3.0 2.1 1 1 1 2 2 2 0 Myo-inositol-1-phosphate synthase Ion_trans_2 PF07885.16 EGR32575.1 - 2.1e-13 50.0 3.3 2.1e-13 50.0 3.3 2.5 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 EGR32575.1 - 0.02 15.0 0.1 0.036 14.1 0.1 1.4 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Sec7 PF01369.20 EGR32576.1 - 2.5e-57 193.5 6.3 4.1e-57 192.8 6.3 1.3 1 0 0 1 1 1 1 Sec7 domain RabGAP-TBC PF00566.18 EGR32577.1 - 6.9e-38 130.4 14.0 8.7e-38 130.1 14.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DUF1931 PF09123.11 EGR32577.1 - 0.021 14.9 2.6 1.3 9.1 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1931) HSF_DNA-bind PF00447.17 EGR32577.1 - 0.19 12.3 2.9 0.21 12.2 1.3 1.9 2 0 0 2 2 2 0 HSF-type DNA-binding Pkinase PF00069.25 EGR32578.1 - 3.4e-61 206.9 0.0 7.7e-61 205.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32578.1 - 2.8e-28 98.9 0.0 5.1e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR32578.1 - 0.002 18.1 0.0 0.005 16.8 0.0 1.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGR32578.1 - 0.017 14.8 5.7 0.076 12.6 0.1 2.8 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGR32578.1 - 0.021 13.6 0.4 0.045 12.5 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase MFAP1 PF06991.11 EGR32578.1 - 1.5 8.6 6.0 0.69 9.7 0.8 2.2 2 0 0 2 2 2 0 Microfibril-associated/Pre-mRNA processing Beach PF02138.18 EGR32579.1 - 3.6e-90 302.1 5.4 6.9e-90 301.2 5.4 1.5 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 EGR32579.1 - 0.00068 20.4 0.0 0.0042 17.9 0.0 2.4 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR32579.1 - 0.0031 17.8 0.0 0.19 12.0 0.0 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain ABC_tran PF00005.27 EGR32580.1 - 2.7e-51 173.7 4.0 2.2e-25 89.8 0.8 3.4 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EGR32580.1 - 2.8e-14 53.6 17.3 0.00053 19.9 0.0 5.4 5 1 1 6 6 6 4 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGR32580.1 - 7.4e-06 26.0 8.3 0.063 13.2 3.2 3.7 2 1 0 2 2 2 2 RsgA GTPase SMC_N PF02463.19 EGR32580.1 - 7.5e-06 25.5 11.6 0.011 15.2 0.3 4.0 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGR32580.1 - 8.7e-06 25.4 1.6 0.035 13.9 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.7 EGR32580.1 - 0.00017 20.9 36.2 0.00017 20.9 36.2 4.7 2 1 2 5 5 3 1 ABC-2 family transporter protein AAA_30 PF13604.6 EGR32580.1 - 0.00044 20.0 0.0 0.57 9.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGR32580.1 - 0.0021 18.1 2.1 2.4 8.3 0.2 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_27 PF13514.6 EGR32580.1 - 0.0024 17.5 0.4 1.2 8.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGR32580.1 - 0.0037 17.6 1.7 2.4 8.6 0.0 3.8 3 0 0 3 3 3 1 RNA helicase T2SSE PF00437.20 EGR32580.1 - 0.0042 16.2 0.4 0.94 8.5 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein Rad17 PF03215.15 EGR32580.1 - 0.0054 16.7 8.6 0.69 9.8 0.0 4.0 3 1 1 4 4 4 2 Rad17 P-loop domain SRP54 PF00448.22 EGR32580.1 - 0.0055 16.4 3.2 0.88 9.2 0.0 2.7 3 0 0 3 3 3 2 SRP54-type protein, GTPase domain AAA_24 PF13479.6 EGR32580.1 - 0.0061 16.3 0.8 12 5.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain DUF87 PF01935.17 EGR32580.1 - 0.0079 16.3 0.1 0.0079 16.3 0.1 3.4 3 0 0 3 3 3 1 Helicase HerA, central domain AAA_16 PF13191.6 EGR32580.1 - 0.018 15.4 0.0 3.3 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 EGR32580.1 - 0.025 14.6 1.5 2 8.4 0.0 3.1 3 1 0 3 3 2 0 AAA domain (dynein-related subfamily) Eaf7 PF07904.13 EGR32580.1 - 0.086 13.2 2.5 0.33 11.3 0.0 2.8 2 0 0 2 2 2 0 Chromatin modification-related protein EAF7 MeaB PF03308.16 EGR32580.1 - 0.15 11.0 0.1 15 4.5 0.0 2.3 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EGR32580.1 - 0.37 11.3 3.3 29 5.2 0.5 3.5 2 1 1 3 3 3 0 AAA domain Zeta_toxin PF06414.12 EGR32580.1 - 0.49 9.7 1.6 14 4.9 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin FHA PF00498.26 EGR32582.1 - 0.0013 19.0 0.0 0.0029 17.9 0.0 1.6 1 0 0 1 1 1 1 FHA domain HHH_3 PF12836.7 EGR32582.1 - 0.0096 16.2 1.2 0.019 15.2 0.1 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif Nup88 PF10168.9 EGR32583.1 - 0.019 12.8 5.9 0.022 12.6 5.9 1.0 1 0 0 1 1 1 0 Nuclear pore component Retro_M PF02813.14 EGR32583.1 - 0.15 12.5 0.2 0.27 11.7 0.2 1.4 1 0 0 1 1 1 0 Retroviral M domain Secretin_N_2 PF07655.13 EGR32583.1 - 1.1 9.9 10.3 0.5 10.9 8.1 1.5 2 0 0 2 2 2 0 Secretin N-terminal domain CRAL_TRIO PF00650.20 EGR32588.1 - 7.1e-23 81.1 2.8 1.4e-20 73.6 2.8 2.4 1 1 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EGR32588.1 - 0.004 17.3 1.0 0.014 15.6 1.0 2.0 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain NuiA PF07924.11 EGR32588.1 - 0.036 14.5 0.0 0.14 12.5 0.0 2.0 1 0 0 1 1 1 0 Nuclease A inhibitor-like protein DUF749 PF05370.11 EGR32588.1 - 0.43 10.7 4.7 8.1 6.6 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF749) Hydrolase PF00702.26 EGR32590.1 - 0.083 13.2 0.0 0.21 11.8 0.0 1.7 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Guanylate_cyc PF00211.20 EGR32591.1 - 5.1e-34 117.5 3.4 6.3e-34 117.2 3.4 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain RRS1 PF04939.12 EGR32592.1 - 1.1e-29 103.4 8.6 1.1e-29 103.4 8.6 2.1 2 0 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) V_ATPase_I PF01496.19 EGR32592.1 - 0.16 9.8 10.4 0.2 9.5 10.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Fucose_iso_N2 PF07882.12 EGR32592.1 - 0.23 11.0 5.5 0.1 12.2 3.2 1.6 1 1 1 2 2 2 0 L-fucose isomerase, second N-terminal domain XhlA PF10779.9 EGR32593.1 - 0.055 13.7 0.6 0.055 13.7 0.6 9.5 5 3 0 6 6 6 0 Haemolysin XhlA Vps53_N PF04100.12 EGR32594.1 - 3.3e-59 200.8 17.9 3.3e-59 200.8 17.9 2.6 3 0 0 3 3 3 1 Vps53-like, N-terminal YnfE PF17452.2 EGR32594.1 - 0.085 13.2 0.3 0.085 13.2 0.3 3.1 3 0 0 3 3 3 0 Uncharacterized YnfE-like Tristanin_u2 PF16638.5 EGR32594.1 - 8.8 7.2 6.0 4.5 8.1 0.0 3.0 3 0 0 3 3 3 0 Unstructured region on methyltransferase between zinc-fingers RRM_1 PF00076.22 EGR32595.1 - 1.6e-17 63.1 0.1 4.2e-17 61.7 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGR32595.1 - 0.00012 21.6 0.1 0.00026 20.6 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGR32595.1 - 0.054 13.6 3.0 0.055 13.6 0.0 2.4 2 1 0 3 3 3 0 RNA recognition motif Tcp10_C PF07202.13 EGR32596.1 - 3.7e-24 85.6 2.4 3.7e-24 85.6 2.4 8.3 4 3 3 7 7 7 2 T-complex protein 10 C-terminus Omega-toxin PF06357.11 EGR32596.1 - 0.43 10.4 4.6 1.6 8.6 4.6 2.0 1 0 0 1 1 1 0 Omega-atracotoxin ALG11_N PF15924.5 EGR32597.1 - 2e-56 191.4 2.4 2e-56 191.4 2.4 2.1 3 0 0 3 3 3 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EGR32597.1 - 8.7e-28 97.0 2.3 1.5e-27 96.2 2.3 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGR32597.1 - 8.8e-12 45.6 0.0 1.3e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EGR32597.1 - 7.5e-06 26.2 0.0 1.6e-05 25.2 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF2113 PF09886.9 EGR32597.1 - 0.013 14.8 0.5 0.077 12.3 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2113) ANAPC4_WD40 PF12894.7 EGR32598.1 - 8.4e-18 64.5 0.5 5e-07 29.9 0.0 4.8 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGR32598.1 - 1.2e-17 63.9 8.9 0.00029 21.6 0.0 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat WD40_like PF17005.5 EGR32598.1 - 3.7e-06 26.5 3.6 0.00097 18.5 0.0 3.7 2 1 1 3 3 3 1 WD40-like domain HPS3_N PF14761.6 EGR32598.1 - 0.011 15.3 0.0 0.21 11.1 0.0 2.7 2 1 1 3 3 3 0 Hermansky-Pudlak syndrome 3 Hira PF07569.11 EGR32598.1 - 0.056 13.2 0.0 16 5.2 0.0 2.7 3 0 0 3 3 3 0 TUP1-like enhancer of split BBS2_N PF14781.6 EGR32598.1 - 0.066 13.1 0.2 0.3 11.0 0.0 2.3 2 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal Kelch_5 PF13854.6 EGR32598.1 - 0.38 10.8 2.2 15 5.7 0.0 3.2 3 0 0 3 3 3 0 Kelch motif AAA PF00004.29 EGR32599.1 - 8.5e-39 133.0 0.0 2.3e-38 131.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGR32599.1 - 2.2e-09 37.0 0.0 8e-09 35.2 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGR32599.1 - 1e-05 25.3 0.0 2.6e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGR32599.1 - 9.3e-05 21.8 1.8 0.00013 21.4 0.0 1.9 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_16 PF13191.6 EGR32599.1 - 0.00015 22.2 0.4 0.0015 19.0 0.4 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EGR32599.1 - 0.00048 20.1 0.0 0.0017 18.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EGR32599.1 - 0.00068 19.4 0.0 0.002 17.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGR32599.1 - 0.0013 19.0 0.4 0.012 15.9 0.4 2.4 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGR32599.1 - 0.0017 17.8 0.5 0.0043 16.5 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGR32599.1 - 0.0029 17.8 0.0 0.0098 16.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGR32599.1 - 0.0034 17.4 0.4 0.014 15.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGR32599.1 - 0.004 17.5 0.2 0.017 15.5 0.0 2.2 2 0 0 2 2 1 1 RNA helicase IstB_IS21 PF01695.17 EGR32599.1 - 0.0042 16.8 0.0 0.014 15.1 0.0 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_2 PF07724.14 EGR32599.1 - 0.0056 16.8 0.2 0.033 14.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_7 PF12775.7 EGR32599.1 - 0.0093 15.5 0.1 0.035 13.6 0.0 2.0 2 0 0 2 2 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 EGR32599.1 - 0.011 16.3 0.0 0.011 16.3 0.0 2.6 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.6 EGR32599.1 - 0.014 15.0 0.1 0.09 12.3 0.2 2.0 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.13 EGR32599.1 - 0.016 14.4 0.2 0.05 12.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF815) NACHT PF05729.12 EGR32599.1 - 0.017 15.1 0.1 0.056 13.4 0.0 1.9 1 1 1 2 2 2 0 NACHT domain Vps4_C PF09336.10 EGR32599.1 - 0.019 15.0 0.3 0.047 13.7 0.3 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain TsaE PF02367.17 EGR32599.1 - 0.026 14.5 0.0 0.092 12.7 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EGR32599.1 - 0.036 14.3 0.0 0.08 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 EGR32599.1 - 0.063 13.1 0.2 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.6 EGR32599.1 - 0.15 12.5 2.7 0.17 12.3 0.0 2.6 3 0 0 3 3 3 0 AAA domain DUF3474 PF11960.8 EGR32599.1 - 0.49 10.6 2.0 9.7 6.4 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3474) ABC_tran PF00005.27 EGR32599.1 - 0.54 10.8 0.0 0.54 10.8 0.0 3.1 3 0 0 3 3 3 0 ABC transporter DUF5352 PF17303.2 EGR32599.1 - 3.9 7.3 7.1 1.2 9.0 0.6 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5352) 4HBT_2 PF13279.6 EGR32600.1 - 0.07 13.6 0.6 0.11 13.0 0.6 1.4 1 0 0 1 1 1 0 Thioesterase-like superfamily Apolipoprotein PF01442.18 EGR32600.1 - 0.089 12.7 0.0 0.12 12.2 0.0 1.2 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain FapA PF03961.13 EGR32600.1 - 0.48 9.0 8.3 0.64 8.6 8.3 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF3584 PF12128.8 EGR32601.1 - 0.0057 14.2 25.6 0.0064 14.1 25.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) YabA PF06156.13 EGR32601.1 - 0.031 14.9 2.3 0.031 14.9 2.3 3.2 1 1 2 3 3 3 0 Initiation control protein YabA bZIP_1 PF00170.21 EGR32601.1 - 0.06 13.4 0.6 0.06 13.4 0.6 4.1 2 1 0 3 3 3 0 bZIP transcription factor Lectin_N PF03954.14 EGR32601.1 - 0.69 9.7 6.8 0.53 10.0 4.6 2.1 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF4358 PF14270.6 EGR32601.1 - 2.2 8.6 12.8 7 7.0 8.5 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4358) Baculo_PEP_C PF04513.12 EGR32601.1 - 3.2 7.8 6.3 1.3 9.1 2.5 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EGR32601.1 - 4.1 7.5 13.1 0.56 10.3 5.5 2.5 2 2 0 2 2 2 0 Protein of unknown function (DUF1664) DUF3437 PF11919.8 EGR32601.1 - 4.5 7.3 6.3 2.8 7.9 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Spc7 PF08317.11 EGR32601.1 - 8.7 5.1 38.1 0.37 9.6 21.0 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein KASH_CCD PF14662.6 EGR32601.1 - 9.4 6.0 40.1 5e+02 0.4 40.1 2.4 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Acyl-CoA_dh_M PF02770.19 EGR32602.1 - 2.8e-15 56.3 0.0 5e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EGR32602.1 - 1.7e-06 28.3 0.0 7.9e-06 26.1 0.0 2.0 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.19 EGR32602.1 - 0.0018 17.9 0.2 0.0036 16.9 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Ribosomal_L18 PF17135.4 EGR32603.1 - 0.049 13.0 0.5 0.1 12.0 0.1 1.6 1 1 1 2 2 2 0 Ribosomal protein 60S L18 and 50S L18e RNA_pol_Rbc25 PF08292.12 EGR32604.1 - 2.3e-10 40.8 2.1 1.3e-06 28.7 0.1 2.1 1 1 1 2 2 2 2 RNA polymerase III subunit Rpc25 Cnd1 PF12717.7 EGR32606.1 - 0.56 10.2 15.7 0.24 11.4 1.0 4.0 4 1 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 cNMP_binding PF00027.29 EGR32607.1 - 2.6e-15 56.2 0.0 4.8e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGR32607.1 - 2e-09 37.3 2.8 3.8e-09 36.4 2.8 1.5 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGR32607.1 - 6.8e-09 35.3 8.0 1.3e-08 34.4 8.0 1.4 1 0 0 1 1 1 1 Ion transport protein DnaA_N PF11638.8 EGR32607.1 - 0.0045 16.7 0.3 0.019 14.7 0.3 2.2 1 0 0 1 1 1 1 DnaA N-terminal domain Ni_hydr_CYTB PF01292.20 EGR32607.1 - 2.7 7.5 8.5 4.5 6.8 0.2 3.0 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 TMEM144 PF07857.12 EGR32607.1 - 8.3 5.3 14.1 0.011 14.7 2.3 2.0 2 0 0 2 2 2 0 Transmembrane family, TMEM144 of transporters PAS_9 PF13426.7 EGR32608.1 - 1.4e-05 25.2 6.7 9.7e-05 22.6 0.1 3.9 3 0 0 3 3 3 1 PAS domain TFIIA PF03153.13 EGR32608.1 - 0.011 15.7 44.4 0.034 14.1 27.1 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Caldesmon PF02029.15 EGR32608.1 - 0.14 10.9 40.9 0.27 10.0 22.5 2.4 2 0 0 2 2 2 0 Caldesmon LAP1C PF05609.12 EGR32608.1 - 0.25 10.4 42.8 0.17 10.9 10.5 2.9 3 0 0 3 3 3 0 Lamina-associated polypeptide 1C (LAP1C) Hemagglutinin PF00509.18 EGR32610.1 - 5.1 5.4 20.3 0.47 8.8 5.4 2.4 1 1 1 2 2 2 0 Haemagglutinin WBS_methylT PF12589.8 EGR32612.1 - 0.22 12.3 4.4 0.46 11.3 4.4 1.5 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome CRAL_TRIO PF00650.20 EGR32613.1 - 3.5e-32 111.3 3.6 4.3e-32 111.0 1.3 1.9 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EGR32613.1 - 0.00012 22.2 0.1 0.00025 21.2 0.1 1.5 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Lipocalin_5 PF13924.6 EGR32613.1 - 0.034 13.9 0.0 0.086 12.6 0.0 1.6 1 1 0 1 1 1 0 Lipocalin-like domain Nuc_sug_transp PF04142.15 EGR32614.1 - 6.4e-09 35.4 2.1 1.2e-08 34.5 2.1 1.4 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 EGR32614.1 - 1e-05 25.7 29.8 6e-05 23.2 4.8 2.9 2 1 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 EGR32614.1 - 2e-05 23.7 9.1 2e-05 23.7 9.1 2.1 2 0 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like TMEM234 PF10639.9 EGR32614.1 - 0.0084 16.1 0.6 0.0084 16.1 0.6 2.3 2 0 0 2 2 2 1 Putative transmembrane family 234 TPT PF03151.16 EGR32614.1 - 0.013 14.9 13.5 0.028 13.7 13.4 1.6 1 1 0 1 1 1 0 Triose-phosphate Transporter family DUF4131 PF13567.6 EGR32614.1 - 0.52 10.0 3.1 0.54 9.9 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Holin_SPP1 PF04688.13 EGR32614.1 - 4.4 7.5 7.8 0.23 11.6 0.7 2.7 3 0 0 3 3 3 0 SPP1 phage holin Voltage_CLC PF00654.20 EGR32615.1 - 0.00025 20.4 0.2 0.00037 19.9 0.2 1.2 1 0 0 1 1 1 1 Voltage gated chloride channel DUF2207 PF09972.9 EGR32615.1 - 0.0029 16.4 2.9 0.0046 15.8 2.9 1.4 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF3169 PF11368.8 EGR32615.1 - 0.037 13.5 7.0 0.5 9.8 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) Presenilin PF01080.17 EGR32615.1 - 0.038 12.8 2.2 0.048 12.4 2.2 1.1 1 0 0 1 1 1 0 Presenilin DUF4271 PF14093.6 EGR32615.1 - 0.41 10.5 2.4 0.38 10.6 0.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) PT-VENN PF04829.13 EGR32615.1 - 1.3 9.2 4.5 2.3 8.4 0.7 2.4 2 0 0 2 2 2 0 Pre-toxin domain with VENN motif PARG_cat PF05028.14 EGR32616.1 - 1.3e-14 54.2 1.3 2.7e-14 53.2 0.5 1.7 2 0 0 2 2 2 1 Poly (ADP-ribose) glycohydrolase (PARG) Ycf15 PF10705.9 EGR32619.1 - 0.1 12.8 0.5 0.22 11.7 0.0 1.8 2 0 0 2 2 2 0 Chloroplast protein precursor Ycf15 putative LRR_4 PF12799.7 EGR32619.1 - 0.83 10.2 7.4 5.1 7.7 2.4 2.9 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) MmgE_PrpD PF03972.14 EGR32620.1 - 1.3e-46 159.0 0.0 1.9e-45 155.3 0.0 1.9 1 1 0 1 1 1 1 MmgE/PrpD family CAP PF00188.26 EGR32621.1 - 0.0065 17.3 4.3 0.014 16.3 4.1 1.7 1 1 0 1 1 1 1 Cysteine-rich secretory protein family Dopey_N PF04118.14 EGR32622.1 - 3e-94 315.6 11.8 3e-94 315.6 11.8 2.3 2 0 0 2 2 2 1 Dopey, N-terminal MFS_1 PF07690.16 EGR32625.1 - 1.7e-26 93.0 24.8 7.7e-26 90.9 15.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1129 PF06570.11 EGR32625.1 - 0.029 13.9 0.8 0.029 13.9 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) DUF4231 PF14015.6 EGR32625.1 - 3.1 8.3 5.5 1.4 9.4 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4231) DUF202 PF02656.15 EGR32625.1 - 7.5 7.1 6.3 3.4 8.2 1.6 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF202) HlyIII PF03006.20 EGR32626.1 - 2.3e-45 155.1 20.6 3.5e-44 151.2 20.6 2.1 1 1 0 1 1 1 1 Haemolysin-III related ATP_synt_H PF05493.13 EGR32626.1 - 0.11 13.0 0.3 0.11 13.0 0.3 3.4 4 0 0 4 4 4 0 ATP synthase subunit H DUF2459 PF09601.10 EGR32626.1 - 3.8 7.3 9.4 8.3 6.2 0.3 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2459) UPF0302 PF08864.10 EGR32627.1 - 0.065 13.3 0.9 0.11 12.5 0.9 1.3 1 0 0 1 1 1 0 UPF0302 domain Clat_adaptor_s PF01217.20 EGR32628.1 - 1.4e-36 125.6 3.8 1.5e-36 125.4 3.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Gp_dh_C PF02800.20 EGR32629.1 - 2.7e-64 215.5 0.0 4.2e-64 214.9 0.0 1.3 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EGR32629.1 - 5.8e-31 106.8 0.1 1.1e-30 106.0 0.1 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DUF2187 PF09953.9 EGR32629.1 - 2 8.5 4.5 35 4.5 0.7 2.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2187) ubiquitin PF00240.23 EGR32630.1 - 0.025 14.3 0.2 0.091 12.5 0.2 2.0 1 0 0 1 1 1 0 Ubiquitin family Rad60-SLD PF11976.8 EGR32630.1 - 0.061 13.2 0.1 0.061 13.2 0.1 3.0 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like Thioredoxin_14 PF18402.1 EGR32631.1 - 0.019 14.9 0.4 0.019 14.9 0.4 3.1 2 1 0 3 3 3 0 Thioredoxin-like domain Phage_tail_T PF06223.12 EGR32631.1 - 0.16 12.5 0.3 3.2 8.3 0.1 2.7 2 0 0 2 2 2 0 Minor tail protein T Kelch_5 PF13854.6 EGR32632.1 - 2.6e-33 113.4 1.1 1.7e-05 24.7 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EGR32632.1 - 2.4e-24 85.0 8.2 2.8e-08 33.9 0.1 7.1 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.6 EGR32632.1 - 6.4e-22 77.3 10.3 2.2e-07 30.8 0.4 5.6 6 0 0 6 6 6 4 Galactose oxidase, central domain Metallophos PF00149.28 EGR32632.1 - 1.6e-13 51.7 0.7 1e-12 49.0 0.1 2.5 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase Kelch_1 PF01344.25 EGR32632.1 - 1e-12 47.4 1.0 0.027 14.0 0.0 5.6 5 1 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 EGR32632.1 - 8.2e-11 41.8 7.0 0.037 14.3 0.0 6.5 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 EGR32632.1 - 1.5e-07 31.1 9.0 0.39 10.8 0.1 6.2 5 1 1 6 6 6 3 Kelch motif RAG2 PF03089.14 EGR32632.1 - 6.1e-06 25.5 0.1 0.037 13.0 0.0 3.3 2 1 1 3 3 3 2 Recombination activating protein 2 STPPase_N PF16891.5 EGR32632.1 - 0.015 15.7 0.3 0.059 13.8 0.3 2.1 1 0 0 1 1 1 0 Serine-threonine protein phosphatase N-terminal domain Peptidase_C12 PF01088.21 EGR32633.1 - 3.4e-50 170.7 3.6 4e-50 170.5 3.6 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 TPR_12 PF13424.6 EGR32634.1 - 8.5e-13 48.4 10.8 1.4e-07 31.7 0.2 4.3 4 1 1 5 5 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGR32634.1 - 1.8e-12 46.5 17.2 0.019 14.8 0.0 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGR32634.1 - 4.4e-11 42.0 11.6 0.02 15.0 0.2 5.0 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGR32634.1 - 1.4e-08 34.3 7.4 0.1 12.9 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGR32634.1 - 2.2e-07 30.4 1.7 0.56 10.4 0.1 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGR32634.1 - 4.2e-05 23.6 1.0 4.9 7.8 0.1 4.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGR32634.1 - 0.00034 20.1 0.4 0.00034 20.1 0.4 1.8 2 0 0 2 2 2 1 MalT-like TPR region TPR_6 PF13174.6 EGR32634.1 - 0.0035 17.9 0.3 1.3 9.8 0.1 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGR32634.1 - 0.047 13.6 7.0 27 4.8 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGR32634.1 - 0.078 12.5 5.3 0.61 9.6 0.1 3.9 4 0 0 4 4 4 0 SHNi-TPR PMSR PF01625.21 EGR32634.1 - 3.3 7.9 12.3 1.2 9.3 1.6 2.8 3 0 0 3 3 3 0 Peptide methionine sulfoxide reductase DUF1981 PF09324.10 EGR32636.1 - 1.3e-22 79.5 6.0 1.3e-22 79.5 6.0 5.6 5 0 0 5 5 5 2 Domain of unknown function (DUF1981) Mon2_C PF16206.5 EGR32636.1 - 8.5e-07 27.5 0.6 5.8e-05 21.4 0.0 2.3 2 0 0 2 2 2 2 C-terminal region of Mon2 protein Jacalin PF01419.17 EGR32636.1 - 0.22 11.4 2.5 7.6 6.5 0.0 3.0 2 1 1 3 3 3 0 Jacalin-like lectin domain DUF5370 PF17340.2 EGR32636.1 - 0.84 9.6 4.0 34 4.4 0.2 3.4 3 0 0 3 3 3 0 Family of unknown function (DUF5370) Sec7_N PF12783.7 EGR32637.1 - 2.5e-30 105.5 12.4 2.5e-30 105.5 12.4 2.5 3 0 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Sec7 PF01369.20 EGR32637.1 - 2.2e-25 89.4 1.0 2.2e-25 89.4 1.0 3.5 3 0 0 3 3 3 1 Sec7 domain DCB PF16213.5 EGR32637.1 - 1.9e-08 34.2 7.5 1.9e-08 34.2 7.5 3.0 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Mak10 PF04112.13 EGR32637.1 - 0.0047 16.4 1.9 0.011 15.3 0.7 2.4 2 0 0 2 2 2 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Yos1 PF08571.10 EGR32637.1 - 0.067 13.5 6.3 0.079 13.2 0.4 2.8 2 0 0 2 2 2 0 Yos1-like Opiods_neuropep PF01160.18 EGR32637.1 - 0.22 11.6 1.9 0.65 10.1 1.9 1.8 1 0 0 1 1 1 0 Vertebrate endogenous opioids neuropeptide Condensin2nSMC PF12422.8 EGR32637.1 - 0.43 10.7 11.6 0.14 12.4 2.7 3.1 2 1 1 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit DUF4473 PF14747.6 EGR32637.1 - 5 7.7 16.0 0.92 10.1 0.4 4.3 4 0 0 4 4 4 0 Domain of unknown function (DUF4473) Il2rg PF15874.5 EGR32639.1 - 4.6e-06 26.8 4.1 0.00094 19.4 0.0 2.8 2 1 0 2 2 2 2 Putative Interleukin 2 receptor, gamma chain Ndc1_Nup PF09531.10 EGR32639.1 - 0.022 13.5 3.8 0.023 13.4 3.8 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Exonuc_VII_L PF02601.15 EGR32639.1 - 0.25 10.9 9.5 0.28 10.7 9.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Vfa1 PF08432.10 EGR32639.1 - 0.37 11.1 23.9 0.58 10.5 23.9 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.6 EGR32639.1 - 2.4 7.4 16.8 2.9 7.2 16.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Cbl_N PF02262.16 EGR32639.1 - 3.2 7.8 10.2 0.57 10.2 1.5 2.2 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 Adaptin_binding PF10199.9 EGR32639.1 - 4.9 7.8 17.3 9.2 6.9 17.3 1.4 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 V_ATPase_I PF01496.19 EGR32639.1 - 5.1 4.9 15.9 7.3 4.4 15.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LMBR1 PF04791.16 EGR32639.1 - 9.9 4.9 13.8 13 4.6 13.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein NAD_binding_6 PF08030.12 EGR32640.1 - 4.7e-20 72.3 3.6 1.7e-19 70.5 0.6 2.4 2 1 0 2 2 2 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 EGR32640.1 - 4.7e-05 24.0 0.0 0.0003 21.4 0.0 2.2 1 1 1 2 2 2 1 Oxidoreductase NAD-binding domain RGS12_us2 PF16611.5 EGR32640.1 - 0.023 15.1 1.8 0.051 14.0 1.8 1.6 1 0 0 1 1 1 0 Unstructured region between RBD and GoLoco Bac_globin PF01152.21 EGR32641.1 - 5e-21 75.1 0.0 5.8e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Bacterial-like globin Pkinase PF00069.25 EGR32643.1 - 4.4e-67 226.2 3.1 4.4e-67 226.2 3.1 2.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32643.1 - 3.1e-44 151.2 0.4 6.2e-44 150.2 0.4 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR32643.1 - 1.6e-09 37.5 0.1 4.7e-09 36.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Pkinase PF00069.25 EGR32644.1 - 2.7e-24 85.9 4.8 3e-24 85.8 4.8 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32644.1 - 1.1e-13 51.0 1.4 1.2e-13 51.0 1.4 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR32644.1 - 1.6e-06 27.7 0.1 2e-06 27.3 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGR32644.1 - 9.7e-05 22.0 0.2 0.00013 21.6 0.2 1.2 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EGR32644.1 - 0.0077 15.2 0.6 0.0086 15.1 0.6 1.1 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGR32644.1 - 0.013 15.4 0.0 0.03 14.2 0.1 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family FTA2 PF13095.6 EGR32644.1 - 0.049 13.2 0.5 0.06 13.0 0.5 1.1 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RTC4 PF14474.6 EGR32644.1 - 0.086 13.0 1.7 0.24 11.6 1.7 1.8 1 1 0 1 1 1 0 RTC4-like domain ARL2_Bind_BART PF11527.8 EGR32644.1 - 0.17 12.0 3.6 0.21 11.7 3.6 1.2 1 0 0 1 1 1 0 The ARF-like 2 binding protein BART DUF3139 PF11337.8 EGR32645.1 - 0.016 15.8 11.7 0.018 15.7 11.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) Peptidase_C2 PF00648.21 EGR32646.1 - 1.5e-62 211.3 0.3 2.6e-62 210.5 0.3 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease PPC PF04151.15 EGR32646.1 - 0.0019 19.2 0.8 0.12 13.5 0.1 3.0 2 1 1 3 3 3 1 Bacterial pre-peptidase C-terminal domain HGD-D PF06050.13 EGR32646.1 - 0.096 12.4 0.0 0.25 11.0 0.0 1.7 2 0 0 2 2 2 0 2-hydroxyglutaryl-CoA dehydratase, D-component Toxin_ToxA PF11584.8 EGR32646.1 - 0.12 12.4 0.0 0.25 11.4 0.0 1.5 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA Ribosomal_S17e PF00833.18 EGR32647.1 - 4.5e-58 194.5 1.4 5e-58 194.3 1.4 1.0 1 0 0 1 1 1 1 Ribosomal S17 SET PF00856.28 EGR32648.1 - 7e-18 65.6 0.6 7e-18 65.6 0.6 4.5 3 3 1 4 4 4 1 SET domain PHD PF00628.29 EGR32648.1 - 5e-13 48.7 6.0 5e-13 48.7 6.0 2.2 2 0 0 2 2 2 1 PHD-finger AWS PF17907.1 EGR32648.1 - 2.6e-07 30.6 17.2 2.6e-07 30.6 17.2 2.4 2 0 0 2 2 2 1 AWS domain DUF2507 PF10702.9 EGR32650.1 - 0.071 13.0 0.0 0.081 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2507) Tim17 PF02466.19 EGR32651.1 - 5.4e-30 104.0 1.8 1e-29 103.2 1.4 1.6 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF3899 PF13038.6 EGR32651.1 - 0.01 16.3 2.2 0.02 15.4 1.5 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) DUF3506 PF12014.8 EGR32651.1 - 0.054 13.5 0.7 1.3 9.0 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3506) MFS_1 PF07690.16 EGR32652.1 - 1.3e-16 60.5 36.0 2e-16 59.9 21.4 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Peptidase_M8 PF01457.16 EGR32653.1 - 8.1e-38 130.4 11.4 3.2e-36 125.1 0.4 3.2 2 1 1 3 3 3 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR32653.1 - 2.3e-05 24.3 8.6 2.3e-05 24.3 8.6 5.9 9 0 0 9 9 9 1 Tenascin EGF domain VSP PF03302.13 EGR32653.1 - 3e-05 23.0 48.3 3e-05 23.0 48.3 4.5 2 1 3 5 5 5 2 Giardia variant-specific surface protein EGF_2 PF07974.13 EGR32653.1 - 6.4e-05 23.2 12.0 6.4e-05 23.2 12.0 8.0 6 3 2 8 8 8 1 EGF-like domain Furin-like_2 PF15913.5 EGR32653.1 - 0.0016 18.6 13.4 0.0016 18.6 13.4 8.4 1 1 6 7 7 7 3 Furin-like repeat, cysteine-rich SOR_SNZ PF01680.17 EGR32654.1 - 1.1e-101 338.9 3.8 1.9e-101 338.1 3.8 1.4 1 0 0 1 1 1 1 SOR/SNZ family SNO PF01174.19 EGR32654.1 - 8.4e-46 156.2 0.3 1.5e-45 155.4 0.3 1.4 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 EGR32654.1 - 3.6e-11 43.0 0.0 7.5e-11 42.0 0.0 1.5 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain ThiG PF05690.14 EGR32654.1 - 2.6e-07 30.2 1.3 0.00018 20.9 0.0 2.4 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG GATase PF00117.28 EGR32654.1 - 6.3e-07 29.4 0.1 1.3e-06 28.3 0.1 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase class-I His_biosynth PF00977.21 EGR32654.1 - 1.6e-05 24.5 0.3 0.0007 19.1 0.0 2.5 2 0 0 2 2 2 1 Histidine biosynthesis protein DJ-1_PfpI PF01965.24 EGR32654.1 - 0.00041 20.2 0.0 0.001 18.9 0.0 1.6 1 0 0 1 1 1 1 DJ-1/PfpI family Peptidase_S51 PF03575.17 EGR32654.1 - 0.00057 19.6 0.0 0.00098 18.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S51 NMO PF03060.15 EGR32654.1 - 0.001 18.5 1.9 0.15 11.4 0.0 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase NanE PF04131.14 EGR32654.1 - 0.0063 15.7 0.3 0.19 10.9 0.0 2.5 2 0 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 EGR32654.1 - 0.0077 15.4 0.0 0.046 12.9 0.0 2.1 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase Dus PF01207.17 EGR32654.1 - 0.0086 15.2 0.0 0.53 9.3 0.0 2.4 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) IMPDH PF00478.25 EGR32654.1 - 0.013 14.6 0.3 0.023 13.7 0.3 1.6 1 1 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain TMP-TENI PF02581.17 EGR32654.1 - 0.026 13.9 0.6 0.13 11.5 0.1 2.1 2 0 0 2 2 2 0 Thiamine monophosphate synthase FMN_dh PF01070.18 EGR32654.1 - 0.036 13.1 0.1 0.086 11.8 0.0 1.6 2 0 0 2 2 2 0 FMN-dependent dehydrogenase CBAH PF02275.18 EGR32655.1 - 0.032 13.9 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 Linear amide C-N hydrolases, choloylglycine hydrolase family Anoctamin PF04547.12 EGR32656.1 - 4.4e-97 325.8 31.1 4.4e-97 325.8 31.1 2.9 4 0 0 4 4 4 1 Calcium-activated chloride channel DUF4520 PF15016.6 EGR32656.1 - 0.13 12.4 1.0 2.5 8.3 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4520) Mer2 PF09074.10 EGR32658.1 - 0.009 15.8 3.7 0.009 15.8 3.7 6.4 4 2 1 5 5 5 2 Mer2 RapH_N PF18801.1 EGR32658.1 - 0.015 15.3 0.9 0.015 15.3 0.9 4.9 5 0 0 5 5 5 0 response regulator aspartate phosphatase H, N terminal Presenilin PF01080.17 EGR32658.1 - 1 8.0 16.8 2 7.1 16.8 1.4 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EGR32658.1 - 1.7 7.7 7.1 3.5 6.8 7.1 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Dapper PF15268.6 EGR32658.1 - 2.7 6.7 15.6 6.6 5.5 15.6 1.6 1 0 0 1 1 1 0 Dapper GH131_N PF18271.1 EGR32659.1 - 0.035 13.8 0.0 0.054 13.2 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 131 catalytic N-terminal domain DUF4858 PF16150.5 EGR32659.1 - 0.074 13.1 2.9 0.13 12.3 2.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4858) HSP70 PF00012.20 EGR32660.1 - 9.3e-222 737.4 18.9 1.1e-221 737.1 18.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGR32660.1 - 6.2e-18 64.7 1.5 1.1e-15 57.3 1.0 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EGR32660.1 - 0.015 15.1 0.0 0.036 13.8 0.0 1.7 1 1 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 EGR32660.1 - 0.016 14.2 0.1 0.39 9.7 0.0 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.20 EGR32660.1 - 0.027 14.0 0.1 0.4 10.1 0.0 2.3 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family Hydantoinase_A PF01968.18 EGR32660.1 - 0.065 12.5 0.2 0.82 8.9 0.1 2.6 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase IES5 PF17335.2 EGR32660.1 - 0.42 10.9 9.6 0.096 13.0 5.1 2.2 2 0 0 2 2 2 0 Ino80 complex subunit 5 Linker_histone PF00538.19 EGR32660.1 - 3.1 8.2 8.2 1.4 9.3 0.3 3.6 3 0 0 3 3 3 0 linker histone H1 and H5 family LAT PF15234.6 EGR32662.1 - 0.087 12.5 0.9 0.088 12.5 0.9 1.0 1 0 0 1 1 1 0 Linker for activation of T-cells ABC_tran PF00005.27 EGR32663.1 - 3.5e-29 102.1 1.3 9.8e-27 94.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 EGR32663.1 - 3.8e-14 52.6 35.2 7.3e-12 45.1 3.2 4.0 3 1 1 4 4 4 2 ABC-2 family transporter protein AAA_21 PF13304.6 EGR32663.1 - 1.4e-07 31.6 0.0 0.00086 19.2 0.0 2.9 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGR32663.1 - 0.0003 20.3 0.3 0.0089 15.5 0.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGR32663.1 - 0.0091 15.9 0.3 0.023 14.6 0.3 1.6 1 0 0 1 1 1 1 RsgA GTPase SbcCD_C PF13558.6 EGR32663.1 - 0.067 13.4 0.0 0.8 10.0 0.0 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_24 PF13479.6 EGR32663.1 - 0.07 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EGR32663.1 - 0.072 12.7 0.5 0.18 11.4 0.1 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 EGR32663.1 - 0.18 12.3 15.4 0.017 15.6 7.9 2.8 1 1 1 2 2 2 0 AAA domain Herpes_BLLF1 PF05109.13 EGR32664.1 - 1.6 6.6 6.6 1.5 6.7 6.6 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) Y_phosphatase PF00102.27 EGR32665.1 - 8.2e-62 208.8 9.5 1.3e-61 208.1 9.5 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGR32665.1 - 8.6e-05 22.7 0.0 0.00019 21.6 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPc PF00782.20 EGR32665.1 - 0.0016 18.3 0.4 0.0016 18.3 0.4 2.7 3 2 1 4 4 4 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGR32665.1 - 0.0063 16.5 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Myotub-related PF06602.14 EGR32665.1 - 0.0064 15.5 2.8 0.036 13.0 2.8 2.2 1 1 0 1 1 1 1 Myotubularin-like phosphatase domain TPR_12 PF13424.6 EGR32666.1 - 5.2e-10 39.5 0.0 2.3e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Thioredoxin PF00085.20 EGR32666.1 - 1.8e-09 37.5 0.2 7.8e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin TPR_10 PF13374.6 EGR32666.1 - 2.8e-06 27.0 0.0 0.0055 16.5 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGR32666.1 - 0.0014 18.6 0.1 0.039 14.1 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Scm3 PF10384.9 EGR32666.1 - 0.0019 17.9 1.9 0.22 11.3 1.0 2.9 2 0 0 2 2 2 1 Centromere protein Scm3 TPR_1 PF00515.28 EGR32666.1 - 0.0044 16.8 0.1 0.014 15.2 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat Redoxin PF08534.10 EGR32666.1 - 0.013 15.2 0.8 0.038 13.7 0.1 2.2 2 1 0 2 2 2 0 Redoxin TPR_MalT PF17874.1 EGR32666.1 - 0.065 12.6 0.7 0.16 11.3 0.2 1.7 1 1 1 2 2 2 0 MalT-like TPR region Thioredoxin_8 PF13905.6 EGR32666.1 - 0.13 12.6 5.0 0.36 11.2 0.0 3.4 3 1 0 3 3 3 0 Thioredoxin-like Cons_hypoth95 PF03602.15 EGR32666.1 - 0.96 9.1 7.8 0.17 11.5 0.7 2.5 2 1 0 3 3 3 0 Conserved hypothetical protein 95 PhyH PF05721.13 EGR32667.1 - 2.8e-30 106.2 0.0 3.6e-30 105.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Asp_Arg_Hydrox PF05118.15 EGR32667.1 - 0.026 14.3 0.0 0.12 12.2 0.0 1.9 2 0 0 2 2 2 0 Aspartyl/Asparaginyl beta-hydroxylase TTL PF03133.15 EGR32668.1 - 4.9e-56 190.0 6.3 4.9e-56 190.0 6.3 1.9 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATP-grasp_3 PF02655.14 EGR32668.1 - 0.03 14.4 0.1 0.077 13.0 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain Peptidase_S30 PF01577.16 EGR32668.1 - 0.072 12.7 3.0 0.15 11.7 3.0 1.5 1 0 0 1 1 1 0 Potyvirus P1 protease CDC45 PF02724.14 EGR32668.1 - 0.12 10.7 5.9 0.18 10.1 5.9 1.2 1 0 0 1 1 1 0 CDC45-like protein ATP-synt_E PF05680.12 EGR32668.1 - 0.35 11.3 3.7 1.1 9.7 3.7 1.8 1 0 0 1 1 1 0 ATP synthase E chain YL1 PF05764.13 EGR32668.1 - 0.39 10.8 9.9 0.015 15.4 4.2 1.6 2 0 0 2 2 2 0 YL1 nuclear protein NPV_P10 PF05531.12 EGR32669.1 - 0.00019 21.8 21.0 0.0013 19.1 3.5 3.0 1 1 1 2 2 2 2 Nucleopolyhedrovirus P10 protein Exonuc_VII_L PF02601.15 EGR32669.1 - 0.00077 19.1 9.4 0.00082 19.0 9.4 1.0 1 0 0 1 1 1 1 Exonuclease VII, large subunit MAD PF05557.13 EGR32669.1 - 0.0014 17.1 21.6 0.0015 17.0 21.6 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein Fez1 PF06818.15 EGR32669.1 - 0.0025 18.3 13.3 0.003 18.0 13.3 1.1 1 0 0 1 1 1 1 Fez1 Atg14 PF10186.9 EGR32669.1 - 0.0078 15.3 15.0 0.017 14.2 15.0 1.6 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 MCPsignal PF00015.21 EGR32669.1 - 0.0082 16.0 7.5 0.011 15.5 7.5 1.3 1 0 0 1 1 1 1 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF4201 PF13870.6 EGR32669.1 - 0.018 14.8 20.1 0.053 13.3 18.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Laminin_II PF06009.12 EGR32669.1 - 0.077 13.0 16.0 0.13 12.3 15.6 1.6 1 1 0 1 1 1 0 Laminin Domain II Spc7 PF08317.11 EGR32669.1 - 0.095 11.6 21.3 0.19 10.6 21.3 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF16 PF01519.16 EGR32669.1 - 0.12 12.8 24.6 7.4 7.1 24.6 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF1664 PF07889.12 EGR32669.1 - 0.21 11.6 18.3 1.1 9.3 9.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Nup54 PF13874.6 EGR32669.1 - 0.22 11.6 9.0 7.5 6.7 8.8 2.5 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Occludin_ELL PF07303.13 EGR32669.1 - 0.26 12.0 12.0 0.42 11.3 6.1 2.1 1 1 1 2 2 2 0 Occludin homology domain Snapin_Pallidin PF14712.6 EGR32669.1 - 0.27 11.7 16.2 4 7.9 10.5 2.6 1 1 1 2 2 2 0 Snapin/Pallidin HrpB7 PF09486.10 EGR32669.1 - 0.3 11.4 7.3 7.7 6.9 4.2 2.5 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) HOOK PF05622.12 EGR32669.1 - 0.52 8.4 20.9 0.12 10.5 13.6 1.7 1 1 0 1 1 1 0 HOOK protein Fib_alpha PF08702.10 EGR32669.1 - 0.54 10.4 21.3 0.71 10.0 21.3 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family V_ATPase_I PF01496.19 EGR32669.1 - 0.71 7.7 13.5 0.73 7.7 13.5 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec34 PF04136.15 EGR32669.1 - 0.73 9.7 14.1 3.7 7.4 6.3 2.4 1 1 1 2 2 2 0 Sec34-like family TMPIT PF07851.13 EGR32669.1 - 1 8.5 13.5 3.4 6.8 13.5 1.7 1 1 0 1 1 1 0 TMPIT-like protein Sec8_exocyst PF04048.14 EGR32669.1 - 1.1 9.2 15.1 13 5.7 15.1 2.1 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain DUF4407 PF14362.6 EGR32669.1 - 1.2 8.4 11.6 1.3 8.3 11.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HIP1_clath_bdg PF16515.5 EGR32669.1 - 1.2 9.8 14.2 3.3 8.4 7.9 2.4 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Vps53_N PF04100.12 EGR32669.1 - 1.3 7.9 18.0 0.061 12.3 8.5 2.0 1 1 1 2 2 2 0 Vps53-like, N-terminal XhlA PF10779.9 EGR32669.1 - 1.5 9.1 33.8 5.4 7.3 11.8 3.1 1 1 2 3 3 3 0 Haemolysin XhlA Syntaxin-6_N PF09177.11 EGR32669.1 - 1.6 9.3 13.2 3.4 8.3 13.0 1.6 1 1 0 1 1 1 0 Syntaxin 6, N-terminal Cauli_AT PF03233.13 EGR32669.1 - 1.7 8.6 24.3 0.32 10.9 11.3 2.1 1 1 1 2 2 2 0 Aphid transmission protein CdvA PF18822.1 EGR32669.1 - 2.1 8.2 22.6 1.1 9.1 15.6 2.3 1 1 1 2 2 2 0 CdvA-like coiled-coil domain AAA_23 PF13476.6 EGR32669.1 - 2.2 8.7 28.0 2.9 8.4 28.0 1.2 1 0 0 1 1 1 0 AAA domain DUF745 PF05335.13 EGR32669.1 - 3.3 7.4 7.8 1.2 8.9 3.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF745) HMMR_N PF15905.5 EGR32669.1 - 4 6.8 23.9 3.4 7.1 20.7 1.8 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Tweety PF04906.13 EGR32669.1 - 4.1 6.0 4.9 4.8 5.7 4.9 1.3 1 0 0 1 1 1 0 Tweety Phage_HK97_TLTM PF06120.11 EGR32669.1 - 4.2 6.5 23.4 2.6 7.1 15.7 2.5 1 1 1 2 2 2 0 Tail length tape measure protein WASH_WAHD PF11945.8 EGR32669.1 - 5 6.6 15.7 2.2 7.7 10.8 2.1 1 1 1 2 2 2 0 WAHD domain of WASH complex USP8_interact PF08941.10 EGR32669.1 - 5.7 6.7 11.7 3.9 7.3 5.0 2.1 1 1 1 2 2 2 0 USP8 interacting DUF948 PF06103.11 EGR32669.1 - 7.2 6.9 11.0 9.3 6.6 2.8 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) GCD14 PF08704.10 EGR32669.1 - 8.3 6.0 8.0 9.9 5.8 8.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Allexi_40kDa PF05549.11 EGR32669.1 - 9 5.7 10.1 17 4.8 8.2 1.9 1 1 1 2 2 2 0 Allexivirus 40kDa protein Kinesin PF00225.23 EGR32670.1 - 1.1e-17 64.0 0.0 1.9e-14 53.3 0.0 2.1 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EGR32670.1 - 1.2e-06 28.5 0.1 2.2e-06 27.7 0.1 1.4 1 0 0 1 1 1 1 Microtubule binding EMP24_GP25L PF01105.24 EGR32671.1 - 4.1e-10 39.9 4.6 4.5e-10 39.7 4.6 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD His_Phos_2 PF00328.22 EGR32672.1 - 2e-21 76.8 12.0 4.7e-19 69.0 10.0 2.6 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 2) ALIX_LYPXL_bnd PF13949.6 EGR32672.1 - 0.0023 17.3 1.5 0.0023 17.3 1.5 1.9 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV DIM1 PF02966.16 EGR32672.1 - 0.37 10.6 5.9 0.26 11.0 0.2 2.3 2 0 0 2 2 2 0 Mitosis protein DIM1 RNA_pol_Rpb2_6 PF00562.28 EGR32674.1 - 1.2e-114 383.4 0.0 2.6e-114 382.3 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_7 PF04560.20 EGR32674.1 - 8.1e-26 90.3 1.0 2.4e-25 88.7 0.1 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EGR32674.1 - 1.1e-23 83.1 0.0 2.5e-23 82.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EGR32674.1 - 1.5e-23 83.4 0.7 3.7e-23 82.1 0.7 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.13 EGR32674.1 - 4.2e-17 62.2 0.0 1.6e-16 60.3 0.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 EGR32674.1 - 2.5e-13 50.4 0.5 6.6e-13 49.0 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 FYVE_2 PF02318.16 EGR32674.1 - 0.021 15.0 0.7 0.057 13.6 0.7 1.7 1 0 0 1 1 1 0 FYVE-type zinc finger TBCA PF02970.16 EGR32675.1 - 4.6e-23 81.3 5.6 4.6e-23 81.3 5.6 1.8 1 1 1 2 2 2 1 Tubulin binding cofactor A HSF_DNA-bind PF00447.17 EGR32675.1 - 0.026 15.1 0.9 0.056 14.1 0.3 1.8 1 1 1 2 2 2 0 HSF-type DNA-binding AAA_34 PF13872.6 EGR32675.1 - 0.034 13.1 1.0 0.064 12.1 0.3 1.6 1 1 1 2 2 2 0 P-loop containing NTP hydrolase pore-1 PMC2NT PF08066.12 EGR32675.1 - 0.048 14.3 1.3 0.088 13.5 0.3 1.8 1 1 1 2 2 2 0 PMC2NT (NUC016) domain DUF4951 PF16309.5 EGR32675.1 - 1.3 9.1 4.1 4.4 7.4 0.2 2.6 1 1 1 2 2 2 0 Domian of unknown function (DUF4951) Iso_dh PF00180.20 EGR32676.1 - 1.3e-76 258.1 0.0 1.5e-76 257.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phe_ZIP PF08916.11 EGR32676.1 - 0.15 12.8 0.9 0.32 11.7 0.1 1.9 2 0 0 2 2 2 0 Phenylalanine zipper PDEase_I PF00233.19 EGR32677.1 - 2.6e-62 210.7 10.1 2.6e-62 210.7 10.1 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 EGR32677.1 - 0.0073 16.5 0.2 0.042 14.1 0.0 2.2 1 1 1 2 2 2 1 HD domain DUF4250 PF14056.6 EGR32677.1 - 0.042 13.8 1.1 16 5.6 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4250) Cas_CXXC_CXXC PF09706.10 EGR32677.1 - 0.081 13.2 0.4 0.18 12.0 0.4 1.5 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_CXXC_CXXC) SIMPL PF04402.14 EGR32679.1 - 7.2e-18 65.8 5.7 8.8e-18 65.5 5.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DUF5021 PF16424.5 EGR32679.1 - 0.011 15.5 0.3 0.014 15.3 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5021) DUF442 PF04273.13 EGR32679.1 - 0.041 14.0 0.1 0.065 13.3 0.1 1.4 1 0 0 1 1 1 0 Putative phosphatase (DUF442) FlgT_N PF16548.5 EGR32679.1 - 1.8 9.2 8.9 0.93 10.1 2.4 3.1 1 1 1 3 3 3 0 Flagellar assembly protein T, N-terminal domain UAE_UbL PF14732.6 EGR32680.1 - 0.037 14.6 0.7 0.13 12.9 0.2 1.9 1 1 1 2 2 2 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain ABC_tran PF00005.27 EGR32681.1 - 1.6e-27 96.7 0.4 2.7e-27 96.0 0.0 1.6 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 EGR32681.1 - 3.5e-20 72.4 32.2 6.9e-20 71.4 32.2 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGR32681.1 - 7.8e-08 32.5 0.0 0.00048 20.0 0.0 2.3 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGR32681.1 - 0.00011 21.7 0.3 0.004 16.6 0.2 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGR32681.1 - 0.00024 21.7 0.2 0.00024 21.7 0.2 2.0 1 1 1 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGR32681.1 - 0.0061 16.5 0.2 0.013 15.4 0.2 1.4 1 0 0 1 1 1 1 RsgA GTPase SbcCD_C PF13558.6 EGR32681.1 - 0.031 14.5 0.0 0.4 10.9 0.0 2.5 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 EGR32681.1 - 0.035 13.7 0.8 0.08 12.6 0.1 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_24 PF13479.6 EGR32681.1 - 0.04 13.6 0.0 0.076 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGR32681.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Cpn60_TCP1 PF00118.24 EGR32682.1 - 2.2e-156 521.4 9.0 2.4e-156 521.2 9.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Cation_ATPase PF13246.6 EGR32682.1 - 0.037 14.1 0.0 0.086 12.9 0.0 1.7 1 0 0 1 1 1 0 Cation transport ATPase (P-type) ID PF18543.1 EGR32683.1 - 0.034 14.2 0.2 0.065 13.3 0.2 1.4 1 0 0 1 1 1 0 Intracellular delivery domain Thioredoxin PF00085.20 EGR32684.1 - 8.3e-23 80.3 0.3 1.2e-22 79.9 0.3 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGR32684.1 - 5.9e-06 26.5 0.1 5.9e-06 26.5 0.1 2.4 1 1 2 3 3 3 1 Thioredoxin-like Thioredoxin_7 PF13899.6 EGR32684.1 - 7.3e-06 26.1 1.0 1.2e-05 25.4 0.3 1.8 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EGR32684.1 - 9.8e-06 26.0 0.3 0.00016 22.1 0.1 2.4 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.6 EGR32684.1 - 1.6e-05 24.9 0.0 2.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin domain AhpC-TSA PF00578.21 EGR32684.1 - 1.9e-05 24.6 0.2 2.6e-05 24.1 0.2 1.4 1 1 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 EGR32684.1 - 0.00016 21.1 1.6 0.0002 20.9 1.6 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 EGR32684.1 - 0.0022 18.2 0.0 0.0041 17.3 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin TraF PF13728.6 EGR32684.1 - 0.0025 17.7 0.7 0.0034 17.2 0.7 1.5 1 1 0 1 1 1 1 F plasmid transfer operon protein Redoxin PF08534.10 EGR32684.1 - 0.014 15.1 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Redoxin Cyclase_polyket PF04673.12 EGR32684.1 - 0.026 14.8 0.4 0.083 13.1 0.3 1.7 2 0 0 2 2 2 0 Polyketide synthesis cyclase DUF836 PF05768.14 EGR32684.1 - 0.027 14.9 0.2 0.044 14.2 0.0 1.5 2 0 0 2 2 1 0 Glutaredoxin-like domain (DUF836) SIP1 PF04938.12 EGR32684.1 - 0.037 13.7 0.2 0.044 13.5 0.2 1.1 1 0 0 1 1 1 0 Survival motor neuron (SMN) interacting protein 1 (SIP1) Baculo_11_kDa PF06143.11 EGR32684.1 - 0.04 13.5 0.2 0.096 12.3 0.2 1.6 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF4290 PF14123.6 EGR32684.1 - 0.059 12.9 1.8 0.14 11.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4290) Ras PF00071.22 EGR32687.1 - 8.5e-59 197.8 1.3 1e-58 197.5 1.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR32687.1 - 2.6e-33 114.8 0.5 3.9e-33 114.2 0.5 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR32687.1 - 7.7e-17 61.3 0.1 9.2e-17 61.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGR32687.1 - 6.5e-06 25.8 0.4 3.7e-05 23.4 0.4 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGR32687.1 - 6.9e-06 25.6 0.2 1.9e-05 24.2 0.2 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGR32687.1 - 4.7e-05 22.8 0.1 6.1e-05 22.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EGR32687.1 - 0.00068 19.2 0.1 0.0025 17.4 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EGR32687.1 - 0.0017 18.4 0.1 0.0029 17.7 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EGR32687.1 - 0.0023 17.7 0.0 0.0029 17.4 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 EGR32687.1 - 0.0066 16.0 0.3 0.021 14.3 0.1 1.8 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF3067 PF11267.8 EGR32687.1 - 0.027 15.1 0.0 0.051 14.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3067) PduV-EutP PF10662.9 EGR32687.1 - 0.074 12.8 0.6 0.69 9.7 0.6 2.3 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EGR32687.1 - 0.16 11.9 0.1 1.5 8.7 0.0 2.2 1 1 1 3 3 3 0 RsgA GTPase Ras PF00071.22 EGR32688.1 - 2.1e-55 186.7 5.2 2.6e-55 186.5 5.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR32688.1 - 9.8e-37 125.8 1.2 9.8e-37 125.8 1.2 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR32688.1 - 2.8e-14 52.9 3.2 3.4e-14 52.7 3.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGR32688.1 - 2.1e-08 34.3 4.8 0.0021 18.0 1.4 2.5 1 1 2 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 EGR32688.1 - 3.1e-08 33.4 1.5 2.3e-07 30.6 0.3 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGR32688.1 - 4.6e-08 32.7 4.6 5.9e-08 32.3 4.6 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGR32688.1 - 1e-06 28.8 0.2 1e-06 28.8 0.2 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGR32688.1 - 0.00022 20.7 2.5 0.00095 18.6 2.5 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 EGR32688.1 - 0.00032 21.1 0.3 0.0034 17.8 0.1 2.1 1 1 1 2 2 2 1 AAA ATPase domain FeoB_N PF02421.18 EGR32688.1 - 0.0011 18.5 1.3 0.083 12.4 1.3 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 EGR32688.1 - 0.0013 19.0 0.1 0.0081 16.4 0.1 2.3 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 EGR32688.1 - 0.0034 16.8 0.6 0.018 14.4 0.0 2.1 2 1 0 2 2 2 1 Bacterial TniB protein AAA_7 PF12775.7 EGR32688.1 - 0.0064 16.0 0.8 0.019 14.5 0.0 1.9 2 1 0 2 2 2 1 P-loop containing dynein motor region AAA_5 PF07728.14 EGR32688.1 - 0.011 15.8 0.1 0.039 14.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EGR32688.1 - 0.048 13.4 4.9 0.26 11.0 4.9 2.1 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EGR32688.1 - 0.067 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 EGR32688.1 - 0.078 12.6 2.0 5.1 6.6 0.1 2.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 EGR32688.1 - 0.17 12.3 2.3 4.8 7.6 2.3 2.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 EGR32688.1 - 0.69 10.4 6.9 6.7 7.2 6.9 2.1 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.6 EGR32688.1 - 1.2 9.1 7.1 0.27 11.3 1.0 2.3 1 1 1 2 2 2 0 AAA domain ATP-synt_D PF01813.17 EGR32689.1 - 0.06 13.2 2.5 0.072 12.9 0.3 1.8 2 0 0 2 2 2 0 ATP synthase subunit D APAF1_C PF17908.1 EGR32689.1 - 0.36 10.8 5.3 4.5 7.3 1.0 2.5 2 1 1 3 3 3 0 APAF-1 helical domain Mtr2 PF10429.9 EGR32689.1 - 0.69 9.8 5.9 0.81 9.6 5.1 1.6 1 1 1 2 2 2 0 Nuclear pore RNA shuttling protein Mtr2 EGF_2 PF07974.13 EGR32690.1 - 0.0017 18.7 10.6 0.0017 18.7 10.6 3.3 3 1 0 3 3 3 1 EGF-like domain EGF_Tenascin PF18720.1 EGR32690.1 - 0.052 13.6 9.5 0.16 12.0 9.5 1.9 1 0 0 1 1 1 0 Tenascin EGF domain Peptidase_M8 PF01457.16 EGR32691.1 - 2.6e-37 128.7 13.3 6.3e-35 120.8 0.6 2.6 2 1 1 3 3 3 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR32691.1 - 0.0027 17.7 5.9 0.0063 16.5 5.9 1.7 1 0 0 1 1 1 1 Tenascin EGF domain Zincin_1 PF06262.11 EGR32691.1 - 0.029 14.5 0.0 0.06 13.4 0.0 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase Peptidase_M8 PF01457.16 EGR32692.1 - 0.007 15.1 0.2 0.24 10.0 0.0 2.0 1 1 1 2 2 2 2 Leishmanolysin Peptidase_M8 PF01457.16 EGR32693.1 - 6.8e-29 100.9 6.1 7.1e-26 91.0 0.1 2.6 1 1 1 2 2 2 2 Leishmanolysin EGF_2 PF07974.13 EGR32693.1 - 0.0002 21.6 11.9 0.0002 21.6 11.9 3.5 3 1 0 3 3 3 1 EGF-like domain EGF_Tenascin PF18720.1 EGR32693.1 - 0.00023 21.1 7.8 0.00023 21.1 7.8 2.7 3 0 0 3 3 3 1 Tenascin EGF domain EGF PF00008.27 EGR32693.1 - 0.92 9.9 15.6 0.14 12.5 7.5 3.1 2 0 0 2 2 2 0 EGF-like domain Peptidase_M8 PF01457.16 EGR32694.1 - 2.6e-41 141.9 5.4 1.6e-39 136.0 5.4 2.0 1 1 0 1 1 1 1 Leishmanolysin EGF_2 PF07974.13 EGR32694.1 - 0.00042 20.6 9.8 0.00042 20.6 9.8 3.6 3 1 0 3 3 3 1 EGF-like domain EGF_Tenascin PF18720.1 EGR32694.1 - 0.00091 19.2 3.5 0.00091 19.2 3.5 2.9 2 0 0 2 2 2 1 Tenascin EGF domain Zincin_1 PF06262.11 EGR32694.1 - 0.2 11.8 0.1 0.38 10.9 0.1 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase Peptidase_M8 PF01457.16 EGR32695.1 - 7e-29 100.9 0.0 1.1e-28 100.3 0.0 1.3 1 1 0 1 1 1 1 Leishmanolysin EGF_Tenascin PF18720.1 EGR32696.1 - 2.9e-05 24.0 4.5 6.1e-05 23.0 4.5 1.5 1 0 0 1 1 1 1 Tenascin EGF domain EGF_2 PF07974.13 EGR32696.1 - 9.8e-05 22.6 9.3 9.8e-05 22.6 9.3 1.7 2 0 0 2 2 2 1 EGF-like domain Peptidase_M8 PF01457.16 EGR32697.1 - 1.6e-27 96.4 0.8 1.7e-27 96.3 0.8 1.0 1 0 0 1 1 1 1 Leishmanolysin VSP PF03302.13 EGR32698.1 - 0.0038 16.1 19.7 0.0038 16.1 19.7 5.9 1 1 5 6 6 6 1 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EGR32698.1 - 0.018 15.2 108.4 0.079 13.1 23.5 5.7 2 2 2 4 4 4 0 Furin-like repeat, cysteine-rich ACOX PF01756.19 EGR32700.1 - 8e-45 152.6 0.2 2.1e-44 151.2 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.24 EGR32700.1 - 8.2e-17 61.8 0.0 1.2e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 EGR32700.1 - 0.00038 20.7 0.0 0.00061 20.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Cas6b_N PF17955.1 EGR32700.1 - 0.034 14.2 0.1 0.099 12.7 0.1 1.8 1 0 0 1 1 1 0 Cas6b N-terminal domain UDPG_MGDP_dh_C PF03720.15 EGR32701.1 - 4.1e-31 107.5 0.0 1.4e-28 99.4 0.0 2.3 2 0 0 2 2 2 2 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh_N PF03721.14 EGR32701.1 - 1.4e-25 90.0 0.0 5.1e-25 88.1 0.0 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EGR32701.1 - 0.0073 16.3 0.1 0.033 14.2 0.0 2.1 2 1 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus MMM1 PF10296.9 EGR32702.1 - 7.3e-05 22.0 1.0 0.046 12.8 0.0 2.5 1 1 2 3 3 3 2 Maintenance of mitochondrial morphology protein 1 SUB1_ProdP9 PF18213.1 EGR32702.1 - 0.13 12.2 0.1 0.27 11.1 0.1 1.5 1 0 0 1 1 1 0 SUB1 protease Prodomain ProdP9 CENP-H PF05837.12 EGR32702.1 - 0.21 12.0 2.3 0.32 11.4 2.3 1.2 1 0 0 1 1 1 0 Centromere protein H (CENP-H) RINGv PF12906.7 EGR32703.1 - 1.4e-12 47.5 4.2 3.8e-12 46.1 4.2 1.8 1 1 0 1 1 1 1 RING-variant domain FHA PF00498.26 EGR32703.1 - 6.4e-11 42.5 0.4 2.5e-10 40.5 0.2 2.1 2 0 0 2 2 2 1 FHA domain Yop-YscD_cpl PF16697.5 EGR32703.1 - 1.8e-06 28.2 0.0 4.1e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain FANCL_C PF11793.8 EGR32703.1 - 0.015 15.5 5.6 0.036 14.2 5.6 1.7 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.6 EGR32703.1 - 0.016 15.5 9.3 0.098 13.0 9.7 2.1 1 1 1 2 2 2 0 Ring finger domain PHD PF00628.29 EGR32703.1 - 0.22 11.5 7.5 9.2 6.2 7.5 2.6 1 1 0 1 1 1 0 PHD-finger Helicase_C PF00271.31 EGR32704.1 - 5.5e-09 36.3 0.6 5.5e-09 36.3 0.6 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Suv3_C_1 PF18147.1 EGR32704.1 - 0.0022 17.8 0.0 0.009 15.9 0.0 2.0 2 0 0 2 2 2 1 Suv3 C-terminal domain 1 DUF5053 PF16476.5 EGR32704.1 - 0.0078 15.9 0.3 0.19 11.4 0.0 3.1 2 1 1 3 3 3 1 Domain of unknown function (DUF5053) CEP1-DNA_bind PF09287.10 EGR32705.1 - 0.00037 20.2 0.5 0.00055 19.6 0.4 1.3 1 1 0 1 1 1 1 CEP-1, DNA binding Sec23_trunk PF04811.15 EGR32706.1 - 4.5e-57 193.4 0.0 7.7e-57 192.6 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EGR32706.1 - 7.6e-25 87.5 0.0 1.7e-24 86.4 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EGR32706.1 - 3.6e-22 78.1 0.2 1.1e-21 76.5 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 EGR32706.1 - 0.0039 17.1 0.0 0.012 15.5 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat SPRY PF00622.28 EGR32707.1 - 5.6e-14 52.3 0.4 7.9e-14 51.8 0.4 1.2 1 0 0 1 1 1 1 SPRY domain DUF4116 PF13475.6 EGR32707.1 - 0.074 12.8 4.2 0.12 12.1 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4116) DUF3800 PF12686.7 EGR32708.1 - 0.029 15.0 15.6 11 6.7 0.0 5.8 2 2 0 2 2 2 0 Protein of unknown function (DUF3800) DUF1041 PF06292.17 EGR32708.1 - 0.22 11.9 11.0 0.083 13.3 6.1 3.0 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1041) SAM_adeno_trans PF01887.16 EGR32708.1 - 1.3 8.4 24.4 5.2 6.4 0.5 6.6 3 1 2 6 6 6 0 S-adenosyl-l-methionine hydroxide adenosyltransferase DUF4349 PF14257.6 EGR32708.1 - 2.8 7.3 9.9 1.4 8.3 3.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) CBFD_NFYB_HMF PF00808.23 EGR32708.1 - 4.9 7.5 21.3 0.52 10.6 0.3 5.3 6 0 0 6 6 6 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone eIF-5a PF01287.20 EGR32710.1 - 1e-26 92.8 0.1 1.7e-26 92.1 0.1 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EGR32710.1 - 0.046 13.8 0.0 0.077 13.0 0.0 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain Abhydrolase_1 PF00561.20 EGR32711.1 - 2.6e-32 112.5 0.0 4.1e-32 111.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGR32711.1 - 7.9e-15 54.8 0.0 1.4e-14 54.0 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGR32711.1 - 2.4e-05 25.1 0.0 3.6e-05 24.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EGR32711.1 - 0.00013 22.0 0.0 0.00025 21.1 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Peptidase_S9 PF00326.21 EGR32711.1 - 0.034 13.6 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 Prolyl oligopeptidase family PhoPQ_related PF10142.9 EGR32711.1 - 0.066 11.9 0.0 0.11 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein Esterase PF00756.20 EGR32711.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative esterase Sugar_tr PF00083.24 EGR32712.1 - 7.4e-37 127.3 19.5 1e-36 126.8 19.5 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGR32712.1 - 4.9e-35 121.1 23.4 1.1e-31 110.1 7.7 2.0 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EGR32712.1 - 2.1e-06 27.3 0.4 0.0084 15.4 0.0 2.4 1 1 1 2 2 2 2 Uncharacterised MFS-type transporter YbfB DUF3007 PF11460.8 EGR32712.1 - 0.0072 16.6 0.1 0.021 15.1 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3007) Caps_synth_CapC PF14102.6 EGR32712.1 - 6.3 7.2 12.8 2.9 8.4 7.0 2.8 2 1 1 3 3 3 0 Capsule biosynthesis CapC Glyco_hydro_38N PF01074.22 EGR32713.1 - 1e-85 287.6 9.8 2.1e-85 286.6 9.8 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EGR32713.1 - 6.1e-32 111.4 3.3 6.1e-32 111.4 3.3 3.3 3 1 1 4 4 4 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EGR32713.1 - 7.9e-20 70.8 0.6 2.3e-19 69.3 0.6 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain S_locus_glycop PF00954.20 EGR32713.1 - 0.0015 19.0 0.7 0.65 10.5 0.0 3.3 2 0 0 2 2 2 2 S-locus glycoprotein domain HSP70 PF00012.20 EGR32714.1 - 3.2e-57 194.1 18.7 3.2e-57 194.1 18.7 3.0 1 1 1 2 2 2 1 Hsp70 protein FGGY_C PF02782.16 EGR32714.1 - 0.013 15.3 0.0 0.034 13.9 0.0 1.7 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, C-terminal domain MreB_Mbl PF06723.13 EGR32714.1 - 0.11 11.3 0.1 0.33 9.7 0.0 1.7 2 0 0 2 2 2 0 MreB/Mbl protein Chorismate_synt PF01264.21 EGR32715.1 - 1.7e-124 414.8 0.0 2.2e-124 414.5 0.0 1.1 1 0 0 1 1 1 1 Chorismate synthase Ephrin PF00812.17 EGR32715.1 - 0.041 13.9 0.8 0.25 11.3 0.3 2.2 2 0 0 2 2 2 0 Ephrin Aminotran_5 PF00266.19 EGR32717.1 - 1.7e-07 30.5 0.0 0.0031 16.5 0.0 2.1 1 1 1 2 2 2 2 Aminotransferase class-V TRL PF13146.6 EGR32717.1 - 0.061 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 TRL-like protein family DUF3955 PF13127.6 EGR32718.1 - 3.3 7.6 8.4 0.18 11.6 1.9 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3955) Tub PF01167.18 EGR32719.1 - 9e-53 179.5 10.5 9e-53 179.5 10.5 1.5 2 0 0 2 2 2 1 Tub family MAS20 PF02064.15 EGR32719.1 - 0.0034 17.5 2.0 0.0034 17.5 2.0 1.6 2 0 0 2 2 2 1 MAS20 protein import receptor Kelch_6 PF13964.6 EGR32722.1 - 5.4e-18 64.6 6.0 0.005 17.1 0.0 6.2 4 2 2 6 6 6 4 Kelch motif Kelch_1 PF01344.25 EGR32722.1 - 1.1e-17 63.3 12.6 5.9e-07 29.0 0.1 6.8 6 1 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 EGR32722.1 - 8.8e-08 32.0 8.0 0.0002 21.3 0.0 5.6 5 1 1 6 6 6 2 Galactose oxidase, central domain zf-RING_UBOX PF13445.6 EGR32722.1 - 2e-07 30.9 6.4 2e-07 30.9 6.4 2.9 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGR32722.1 - 4.4e-07 30.1 7.3 4.4e-07 30.1 7.3 3.0 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGR32722.1 - 5.8e-07 29.3 8.8 5.8e-07 29.3 8.8 2.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGR32722.1 - 3.8e-06 26.6 8.0 3.8e-06 26.6 8.0 2.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGR32722.1 - 9.4e-06 25.5 6.3 9.4e-06 25.5 6.3 2.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-B_box PF00643.24 EGR32722.1 - 2.1e-05 24.6 10.5 2.1e-05 24.6 10.5 3.3 3 0 0 3 3 3 1 B-box zinc finger Kelch_3 PF13415.6 EGR32722.1 - 4.8e-05 23.5 0.5 7.4 7.0 0.0 4.9 6 0 0 6 6 5 2 Galactose oxidase, central domain zf-RING_4 PF14570.6 EGR32722.1 - 0.00011 21.9 8.1 0.00011 21.9 8.1 3.5 2 1 0 2 2 2 1 RING/Ubox like zinc-binding domain Kelch_5 PF13854.6 EGR32722.1 - 0.00025 21.0 1.6 0.51 10.4 0.0 4.5 5 0 0 5 5 5 1 Kelch motif zf-C3HC4_4 PF15227.6 EGR32722.1 - 0.005 17.0 10.7 0.005 17.0 10.7 3.3 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGR32722.1 - 0.0065 16.3 7.7 0.0065 16.3 7.7 2.8 2 1 0 2 2 1 1 Prokaryotic RING finger family 4 Methyltransf_14 PF08484.11 EGR32722.1 - 0.037 13.8 6.3 0.15 11.9 0.6 2.5 2 0 0 2 2 2 0 C-methyltransferase C-terminal domain SBP PF03110.14 EGR32722.1 - 0.13 12.6 7.7 0.55 10.6 7.7 2.1 1 0 0 1 1 1 0 SBP domain DUF2316 PF10078.9 EGR32722.1 - 0.49 10.7 0.0 0.49 10.7 0.0 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Histidinol_dh PF00815.20 EGR32722.1 - 0.66 8.9 6.8 1.2 8.0 6.8 1.4 1 0 0 1 1 1 0 Histidinol dehydrogenase zf-RING_10 PF16685.5 EGR32722.1 - 8 6.7 19.1 0.029 14.5 5.8 2.9 1 1 1 2 2 2 0 zinc RING finger of MSL2 DUF3038 PF11237.8 EGR32723.1 - 0.094 12.7 2.4 0.075 13.1 0.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3038) ECH_1 PF00378.20 EGR32724.1 - 1.1e-29 103.5 0.0 1.3e-29 103.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGR32724.1 - 3.1e-21 76.2 0.0 3.6e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase TMEM132D_C PF15706.5 EGR32724.1 - 0.15 11.9 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Ion_trans PF00520.31 EGR32725.1 - 6.8e-141 467.6 96.3 1.5e-49 168.4 31.7 3.1 3 0 0 3 3 3 3 Ion transport protein PKD_channel PF08016.12 EGR32725.1 - 6.2e-06 25.2 83.0 0.00037 19.3 17.2 6.8 3 3 2 6 6 6 4 Polycystin cation channel DUF3382 PF11862.8 EGR32725.1 - 0.27 11.5 8.4 0.36 11.1 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF3382) Ion_trans PF00520.31 EGR32726.1 - 3.9e-62 209.7 22.7 5.9e-62 209.1 22.7 1.3 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 EGR32726.1 - 0.00084 18.1 31.4 0.0099 14.6 3.0 3.8 3 1 2 5 5 5 3 Polycystin cation channel Slu7 PF11708.8 EGR32726.1 - 1.7 8.3 5.4 3 7.5 5.4 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Corona_NS3b PF03053.14 EGR32728.1 - 0.15 11.8 3.7 0.19 11.4 3.7 1.0 1 0 0 1 1 1 0 ORF3b coronavirus protein RIH_assoc PF08454.11 EGR32730.1 - 2.8e-21 75.3 11.0 2.8e-21 75.3 11.0 5.8 2 2 2 4 4 4 1 RyR and IP3R Homology associated Ion_trans PF00520.31 EGR32730.1 - 2.8e-08 33.3 31.0 8.6e-08 31.7 31.0 1.9 1 0 0 1 1 1 1 Ion transport protein Furin-like_2 PF15913.5 EGR32731.1 - 1.5e-25 89.4 138.4 2.7e-07 30.7 15.9 6.7 1 1 6 7 7 7 6 Furin-like repeat, cysteine-rich VSP PF03302.13 EGR32731.1 - 2.1e-07 30.2 113.6 0.12 11.2 11.6 7.0 1 1 6 7 7 7 7 Giardia variant-specific surface protein Furin-like PF00757.20 EGR32731.1 - 2.2e-07 30.9 108.8 0.013 15.4 37.9 4.0 1 1 4 5 5 5 5 Furin-like cysteine rich region PHF5 PF03660.14 EGR32731.1 - 0.00038 20.6 98.6 0.32 11.2 7.7 7.1 1 1 6 7 7 7 5 PHF5-like protein GF_recep_IV PF14843.6 EGR32731.1 - 0.00039 20.2 117.0 0.022 14.6 28.8 5.1 1 1 5 6 6 6 4 Growth factor receptor domain IV Hormone_4 PF00220.17 EGR32731.1 - 2.1 8.6 15.9 58 4.1 1.1 6.6 5 0 0 5 5 5 0 Neurohypophysial hormones, N-terminal Domain SWIRM-assoc_1 PF16495.5 EGR32732.1 - 0.13 12.2 4.0 0.91 9.5 4.0 2.5 1 0 0 1 1 1 0 SWIRM-associated region 1 ABC_tran PF00005.27 EGR32733.1 - 5e-48 163.1 1.6 8.7e-27 94.3 0.4 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGR32733.1 - 1.2e-08 34.6 20.5 0.017 14.6 0.0 4.2 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGR32733.1 - 5.6e-08 32.9 18.8 0.054 13.3 0.0 5.4 3 2 2 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_membrane PF00664.23 EGR32733.1 - 5.8e-07 29.4 8.5 5.8e-07 29.4 8.5 1.8 2 0 0 2 2 2 1 ABC transporter transmembrane region RsgA_GTPase PF03193.16 EGR32733.1 - 7.5e-07 29.2 0.6 0.026 14.4 0.2 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EGR32733.1 - 1.2e-05 25.7 0.0 0.052 13.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_7 PF12775.7 EGR32733.1 - 1.6e-05 24.5 0.1 0.17 11.4 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region NB-ARC PF00931.22 EGR32733.1 - 8.5e-05 21.9 0.1 2.1 7.5 0.0 3.6 3 1 0 3 3 3 2 NB-ARC domain AAA_29 PF13555.6 EGR32733.1 - 9e-05 22.1 0.1 0.59 9.9 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EGR32733.1 - 0.00022 21.5 1.0 1.7 8.9 0.9 3.3 2 1 0 2 2 2 2 AAA domain T2SSE PF00437.20 EGR32733.1 - 0.00027 20.1 0.0 0.15 11.1 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA PF00004.29 EGR32733.1 - 0.00041 20.8 0.5 3.4 8.1 0.9 3.3 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EGR32733.1 - 0.00054 19.2 0.2 0.27 10.4 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) MMR_HSR1 PF01926.23 EGR32733.1 - 0.00069 19.7 0.5 1.5 8.9 0.1 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase RNA_helicase PF00910.22 EGR32733.1 - 0.002 18.5 1.5 0.7 10.3 0.0 4.0 4 0 0 4 4 4 1 RNA helicase Zeta_toxin PF06414.12 EGR32733.1 - 0.0028 17.0 0.0 0.36 10.1 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin NACHT PF05729.12 EGR32733.1 - 0.0036 17.2 0.2 0.19 11.6 0.0 2.9 3 0 0 3 3 3 1 NACHT domain TsaE PF02367.17 EGR32733.1 - 0.0038 17.2 0.0 0.94 9.5 0.0 2.8 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EGR32733.1 - 0.0064 16.1 0.0 0.47 10.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 EGR32733.1 - 0.01 15.5 0.6 0.49 10.0 0.1 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain FtsK_SpoIIIE PF01580.18 EGR32733.1 - 0.034 13.5 0.0 2.6 7.3 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.19 EGR32733.1 - 0.036 13.7 0.2 4.3 6.9 0.0 2.9 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Roc PF08477.13 EGR32733.1 - 0.04 14.1 0.1 8 6.7 0.0 3.1 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SbcCD_C PF13558.6 EGR32733.1 - 0.14 12.4 2.6 4.9 7.4 0.1 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.17 EGR32733.1 - 0.15 11.8 0.5 6.1 6.5 0.0 3.1 3 0 0 3 3 3 0 IstB-like ATP binding protein Dynamin_N PF00350.23 EGR32733.1 - 0.18 11.9 7.7 7.1 6.7 0.0 4.0 3 1 0 3 3 3 0 Dynamin family Peptidase_S10 PF00450.22 EGR32735.1 - 2e-109 366.8 3.8 2.3e-109 366.6 3.8 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Ins145_P3_rec PF08709.11 EGR32737.1 - 2.3e-12 46.6 30.2 7.6e-12 44.9 19.3 3.8 2 2 1 3 3 3 2 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 EGR32737.1 - 1.9e-07 31.1 0.3 1.9e-07 31.1 0.3 5.5 4 2 0 4 4 4 1 MIR domain RicinB_lectin_2 PF14200.6 EGR32737.1 - 0.039 14.7 0.3 0.039 14.7 0.3 2.6 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like RIH_assoc PF08454.11 EGR32738.1 - 5.9e-32 109.5 1.4 5.9e-32 109.5 1.4 7.2 7 3 0 7 7 7 2 RyR and IP3R Homology associated Pkinase PF00069.25 EGR32739.1 - 1.7e-21 76.8 0.1 2e-21 76.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32739.1 - 1e-13 51.2 0.0 1.2e-13 51.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR32739.1 - 4.1e-09 35.7 0.0 6e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR32739.1 - 0.0006 19.2 0.1 0.00085 18.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EGR32739.1 - 0.0041 16.2 0.5 0.0065 15.5 0.5 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase YrbL-PhoP_reg PF10707.9 EGR32739.1 - 0.0099 15.4 0.1 0.021 14.4 0.1 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 EGR32739.1 - 0.033 14.1 0.0 0.076 12.9 0.0 1.6 1 1 0 1 1 1 0 Phosphotransferase enzyme family CRAL_TRIO PF00650.20 EGR32740.1 - 1.2e-29 103.1 0.7 2.7e-29 101.9 0.7 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EGR32740.1 - 0.035 14.3 0.2 0.069 13.3 0.2 1.5 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Gb3_synth PF04572.12 EGR32740.1 - 0.2 11.9 10.5 0.85 9.8 0.4 2.7 1 1 0 2 2 2 0 Alpha 1,4-glycosyltransferase conserved region RRM_1 PF00076.22 EGR32741.1 - 1.4e-17 63.3 0.1 9.2e-12 44.6 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGR32741.1 - 0.00014 21.9 0.1 0.0011 19.1 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif TFIIF_alpha PF05793.12 EGR32742.1 - 0.055 12.1 21.2 0.061 11.9 21.2 1.0 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Coilin_N PF15862.5 EGR32742.1 - 1.8 8.4 20.1 2.2 8.1 20.1 1.1 1 0 0 1 1 1 0 Coilin N-terminus BSMAP PF12280.8 EGR32742.1 - 6.5 6.9 8.2 6.6 6.9 8.2 1.1 1 0 0 1 1 1 0 Brain specific membrane anchored protein TP53IP5 PF15331.6 EGR32742.1 - 7.9 6.6 13.0 8.7 6.4 13.0 1.0 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 MORN PF02493.20 EGR32743.1 - 5.4e-45 148.7 46.3 3e-07 29.9 1.1 8.4 8 0 0 8 8 8 8 MORN repeat Clat_adaptor_s PF01217.20 EGR32744.1 - 3.5e-51 172.9 3.8 4e-51 172.7 3.8 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TFIID_NTD2 PF04494.15 EGR32744.1 - 0.015 15.5 0.9 0.027 14.7 0.9 1.5 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit, NTD2 domain CNOT1_TTP_bind PF16417.5 EGR32746.1 - 3.4e-44 150.3 17.2 3.4e-44 150.3 17.2 3.0 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain Not1 PF04054.15 EGR32746.1 - 4.9e-44 150.7 7.5 4.9e-44 150.7 7.5 5.7 5 3 1 6 6 6 2 CCR4-Not complex component, Not1 DUF3819 PF12842.7 EGR32746.1 - 7.1e-41 139.5 8.0 7.1e-41 139.5 8.0 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3819) U62_UL91 PF17442.2 EGR32746.1 - 0.028 14.4 0.5 0.028 14.4 0.5 3.0 3 0 0 3 3 3 0 Functional domain of U62 and UL91 proteins KH_8 PF17903.1 EGR32746.1 - 2.6 8.2 9.3 24 5.1 0.6 4.2 2 1 1 3 3 3 0 Krr1 KH1 domain Kinesin PF00225.23 EGR32747.1 - 2.3e-55 187.8 0.9 3e-55 187.5 0.9 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR32747.1 - 6.2e-23 81.4 1.1 1.8e-21 76.6 0.0 2.6 2 1 1 3 3 3 1 Microtubule binding Clr2 PF10383.9 EGR32748.1 - 0.11 13.3 0.1 0.15 12.8 0.1 1.2 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 Pkinase PF00069.25 EGR32749.1 - 1.4e-77 260.6 0.1 2.6e-77 259.8 0.1 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32749.1 - 4.5e-39 134.3 0.1 2.9e-38 131.6 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR32749.1 - 4.9e-09 35.9 0.2 8.1e-08 31.9 0.2 2.1 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGR32749.1 - 7.8e-05 22.3 1.9 0.00013 21.7 1.9 1.3 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 EGR32749.1 - 0.00027 20.6 2.8 0.042 13.5 1.6 2.2 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGR32749.1 - 0.029 13.7 1.7 0.035 13.5 0.0 1.9 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family MRP-63 PF14978.6 EGR32749.1 - 0.088 13.4 3.8 0.12 13.0 0.2 2.4 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 Ion_trans PF00520.31 EGR32750.1 - 1.7e-14 53.7 25.8 2.8e-14 52.9 25.8 1.3 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EGR32750.1 - 1.6e-13 50.5 0.0 2.8e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGR32750.1 - 7.3e-13 48.3 3.7 7.3e-13 48.3 3.7 1.9 2 0 0 2 2 2 1 Ion channel TetR_C_2 PF08361.11 EGR32750.1 - 0.0023 18.0 0.2 0.0087 16.2 0.2 2.0 1 0 0 1 1 1 1 MAATS-type transcriptional repressor, C-terminal region Lig_chan PF00060.26 EGR32750.1 - 0.02 14.7 0.2 0.041 13.7 0.2 1.7 1 0 0 1 1 1 0 Ligand-gated ion channel TcfC PF16967.5 EGR32750.1 - 0.083 12.4 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 E-set like domain IGPD PF00475.18 EGR32750.1 - 0.13 12.5 0.0 0.34 11.2 0.0 1.6 1 0 0 1 1 1 0 Imidazoleglycerol-phosphate dehydratase UPF0147 PF03685.13 EGR32750.1 - 0.14 12.2 1.1 1 9.4 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0147) MitMem_reg PF13012.6 EGR32750.1 - 0.58 10.6 9.7 2.9 8.4 0.9 3.1 2 2 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF1664 PF07889.12 EGR32750.1 - 4.7 7.3 7.3 0.4 10.7 2.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Sugar_tr PF00083.24 EGR32751.1 - 1.4e-49 169.2 22.4 1.7e-49 168.9 22.4 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGR32751.1 - 9.9e-28 97.1 18.4 8.3e-27 94.0 12.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 EGR32751.1 - 1.9e-05 23.7 26.3 6.5e-05 22.0 5.3 2.3 1 1 1 2 2 2 2 MFS_1 like family MFS_4 PF06779.14 EGR32751.1 - 0.011 15.1 5.7 0.02 14.2 0.9 2.3 2 1 0 2 2 2 0 Uncharacterised MFS-type transporter YbfB LapA_dom PF06305.11 EGR32751.1 - 0.014 15.2 0.2 4.6 7.1 0.1 3.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain MFS_2 PF13347.6 EGR32751.1 - 0.75 8.3 31.9 0.014 14.0 9.1 3.3 2 2 1 3 3 3 0 MFS/sugar transport protein Fer2_3 PF13085.6 EGR32752.1 - 4.2e-26 91.1 0.0 7.9e-26 90.2 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_7 PF12838.7 EGR32752.1 - 4.7e-10 39.9 0.5 0.00062 20.3 5.6 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGR32752.1 - 1.2e-09 38.4 15.2 3.6e-07 30.5 3.3 2.6 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_17 PF13534.6 EGR32752.1 - 2.9e-08 34.1 1.8 2.9e-08 34.1 1.8 2.4 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGR32752.1 - 5.2e-07 29.7 1.0 5.2e-07 29.7 1.0 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EGR32752.1 - 0.011 15.7 0.9 0.011 15.7 0.9 2.5 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain Fer4_9 PF13187.6 EGR32752.1 - 0.012 15.8 8.6 0.32 11.2 5.7 3.0 2 1 2 4 4 4 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 EGR32752.1 - 1.6 8.9 11.9 2.5 8.3 1.1 3.3 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_16 PF13484.6 EGR32752.1 - 6.8 7.7 13.6 0.61 11.1 4.9 3.0 2 1 0 2 2 2 0 4Fe-4S double cluster binding domain Fer4_6 PF12837.7 EGR32752.1 - 9.1 6.5 16.9 1.3 9.2 1.2 3.6 3 0 0 3 3 3 0 4Fe-4S binding domain RIBIOP_C PF04950.12 EGR32753.1 - 6.8e-78 262.0 3.8 6.8e-78 262.0 3.8 4.6 5 2 1 6 6 6 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EGR32753.1 - 1.4e-18 66.7 0.0 1.4e-18 66.7 0.0 3.3 3 1 0 3 3 3 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 EGR32753.1 - 0.001 18.7 4.7 0.001 18.7 4.7 4.1 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 EGR32753.1 - 0.0013 18.8 0.0 0.0013 18.8 0.0 3.3 3 2 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EGR32753.1 - 0.0045 17.4 0.3 0.028 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGR32753.1 - 0.01 16.1 0.3 0.038 14.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EGR32753.1 - 0.02 15.3 0.1 0.063 13.7 0.1 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGR32753.1 - 0.023 15.1 0.8 0.073 13.5 0.0 2.4 2 0 0 2 2 2 0 RNA helicase DSPn PF14671.6 EGR32754.1 - 3.8e-49 166.8 0.0 9.4e-49 165.5 0.0 1.6 1 0 0 1 1 1 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 EGR32754.1 - 2.1e-15 56.7 0.0 1.2e-14 54.3 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGR32754.1 - 5e-06 26.2 0.0 1.1e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGR32754.1 - 0.0029 17.7 0.0 0.0071 16.5 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.12 EGR32754.1 - 0.061 13.0 0.0 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) NIF PF03031.18 EGR32757.1 - 1.1e-50 171.4 0.4 1.4e-50 171.1 0.4 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF3818 PF12825.7 EGR32757.1 - 0.0012 18.0 0.5 0.0025 16.9 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function in PX-proteins (DUF3818) Sedlin_N PF04628.13 EGR32757.1 - 0.025 14.7 0.1 0.04 14.0 0.1 1.4 1 1 0 1 1 1 0 Sedlin, N-terminal conserved region MFP2b PF12150.8 EGR32757.1 - 0.13 11.5 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Cytosolic motility protein Pkinase PF00069.25 EGR32758.1 - 2.1e-35 122.4 0.0 2.3e-35 122.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32758.1 - 3.6e-22 78.9 0.0 4.2e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR32758.1 - 8.6e-05 22.0 0.0 0.0001 21.7 0.0 1.1 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR32758.1 - 0.0006 18.7 0.0 0.00071 18.5 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EGR32758.1 - 0.079 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL GAF_2 PF13185.6 EGR32759.1 - 1e-07 32.3 0.0 4.7e-05 23.7 0.0 2.2 2 0 0 2 2 2 2 GAF domain GAF PF01590.26 EGR32759.1 - 0.0025 18.4 0.0 0.46 11.1 0.0 2.2 2 0 0 2 2 2 2 GAF domain PADR1 PF08063.12 EGR32760.1 - 1.3e-14 53.7 1.6 1.4e-14 53.5 1.6 1.1 1 0 0 1 1 1 1 PADR1 (NUC008) domain DUF4503 PF14951.6 EGR32760.1 - 0.073 11.5 0.0 0.077 11.4 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) Anoctamin PF04547.12 EGR32761.1 - 1.7e-06 27.2 16.0 2.9e-06 26.4 16.0 1.4 1 0 0 1 1 1 1 Calcium-activated chloride channel RSN1_7TM PF02714.15 EGR32761.1 - 0.00064 19.1 21.0 0.0014 18.0 21.0 1.6 1 1 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate DUF4149 PF13664.6 EGR32761.1 - 0.0047 17.2 1.6 0.0047 17.2 1.6 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4149) Gp_dh_N PF00044.24 EGR32761.1 - 0.037 14.4 0.1 1.9 8.9 0.0 2.6 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Phage_holin_4_2 PF04020.13 EGR32761.1 - 9.4 7.0 10.3 40 4.9 4.7 3.2 2 1 0 2 2 2 0 Mycobacterial 4 TMS phage holin, superfamily IV Pkinase PF00069.25 EGR32762.1 - 1.7e-29 103.0 1.8 3e-29 102.2 1.8 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32762.1 - 7.6e-17 61.4 0.5 1.1e-16 60.9 0.5 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ART PF01129.18 EGR32762.1 - 0.12 11.7 2.9 0.2 10.9 0.2 2.1 2 0 0 2 2 2 0 NAD:arginine ADP-ribosyltransferase FTA2 PF13095.6 EGR32762.1 - 0.18 11.4 4.6 2.1 7.9 0.6 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 PHD PF00628.29 EGR32763.1 - 2.3e-05 24.2 20.4 0.00013 21.8 13.8 2.9 1 1 1 2 2 2 1 PHD-finger C1_1 PF00130.22 EGR32763.1 - 0.0025 17.7 8.2 0.0025 17.7 8.2 3.5 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 EGR32763.1 - 0.035 14.4 12.5 4 7.8 2.9 3.6 3 0 0 3 3 3 0 C1 domain Toxin_34 PF08396.10 EGR32763.1 - 0.037 14.8 4.9 0.037 14.8 4.9 2.8 2 1 1 3 3 3 0 Spider toxin omega agatoxin/Tx1 family CSG2 PF16965.5 EGR32763.1 - 8.4 5.2 8.4 1.7 7.5 0.5 2.0 2 0 0 2 2 2 0 Ceramide synthase regulator DZR PF12773.7 EGR32763.1 - 8.6 6.5 20.3 77 3.4 5.0 3.1 1 1 1 2 2 2 0 Double zinc ribbon Polysacc_synt_C PF14667.6 EGR32764.1 - 3.2 7.8 15.4 0.22 11.5 7.5 2.2 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain PHM7_cyt PF14703.6 EGR32765.1 - 5.9e-10 39.7 3.7 5.9e-10 39.7 3.7 2.7 2 1 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter HDOD PF08668.12 EGR32765.1 - 0.022 14.2 0.1 0.063 12.7 0.0 1.7 2 0 0 2 2 2 0 HDOD domain SDH_beta PF03315.15 EGR32765.1 - 0.081 13.3 0.0 0.19 12.1 0.0 1.6 1 0 0 1 1 1 0 Serine dehydratase beta chain C2 PF00168.30 EGR32766.1 - 4.2e-06 27.0 0.0 0.0032 17.7 0.0 3.2 3 0 0 3 3 3 2 C2 domain TSC22 PF01166.18 EGR32766.1 - 0.03 14.6 0.6 0.03 14.6 0.6 4.9 3 1 4 7 7 7 0 TSC-22/dip/bun family Sod_Cu PF00080.20 EGR32767.1 - 1.7e-45 154.7 4.2 1.9e-45 154.5 4.2 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Pkinase PF00069.25 EGR32768.1 - 2.3e-70 237.0 0.7 2.5e-70 236.8 0.7 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32768.1 - 4.7e-46 157.2 0.1 5.5e-46 157.0 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR32768.1 - 1.1e-07 31.0 0.0 1.6e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGR32768.1 - 4.2e-06 26.3 0.5 0.00042 19.7 0.1 2.6 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGR32768.1 - 1.2e-05 24.5 2.6 1.9e-05 23.8 2.6 1.3 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EGR32768.1 - 0.0008 19.1 1.0 0.0016 18.1 0.8 1.5 1 1 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGR32768.1 - 0.0021 17.5 0.0 0.0034 16.8 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4347 PF14252.6 EGR32768.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) APH PF01636.23 EGR32768.1 - 0.028 14.3 0.0 0.086 12.7 0.0 1.6 1 1 0 2 2 2 0 Phosphotransferase enzyme family End_N_terminal PF12218.8 EGR32768.1 - 0.081 12.6 0.1 0.27 11.0 0.0 1.9 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Pkinase PF00069.25 EGR32769.1 - 5.3e-61 206.3 5.8 6e-61 206.1 5.8 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32769.1 - 4.7e-40 137.5 0.6 6.1e-40 137.1 0.6 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR32769.1 - 3.1e-06 26.7 0.3 4.8e-06 26.1 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGR32769.1 - 4.7e-06 26.1 0.7 7.1e-06 25.5 0.3 1.5 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR32769.1 - 1.1e-05 24.4 0.1 2e-05 23.5 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EGR32769.1 - 9.5e-05 21.5 3.7 0.00013 21.0 3.7 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGR32769.1 - 0.004 17.1 0.1 0.0094 15.9 0.1 1.5 1 1 0 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGR32769.1 - 0.2 11.2 5.6 0.48 10.0 2.9 2.2 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 NAD_binding_5 PF07994.12 EGR32770.1 - 1.6e-142 474.7 0.1 2.3e-142 474.1 0.1 1.2 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EGR32770.1 - 5.2e-44 149.0 1.0 1.1e-43 147.9 1.0 1.6 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase FUR PF01475.19 EGR32770.1 - 0.00096 19.3 0.0 0.0028 17.8 0.0 1.7 1 0 0 1 1 1 1 Ferric uptake regulator family ATP19 PF11022.8 EGR32771.1 - 0.043 14.2 0.1 0.083 13.3 0.1 1.5 1 0 0 1 1 1 0 ATP synthase subunit K CREPT PF16566.5 EGR32771.1 - 0.092 12.9 2.9 0.13 12.5 2.9 1.1 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour IKI3 PF04762.12 EGR32772.1 - 8e-141 470.9 24.4 3.5e-124 415.9 20.1 2.1 1 1 1 2 2 2 2 IKI3 family Cation_ATPase_C PF00689.21 EGR32773.1 - 1.3e-38 132.5 5.3 1.3e-38 132.5 5.3 1.9 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGR32773.1 - 4.8e-35 120.7 4.5 1.8e-34 118.8 0.5 2.7 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGR32773.1 - 1.8e-18 66.4 0.5 7.3e-18 64.4 0.0 2.3 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGR32773.1 - 2.9e-17 63.6 1.7 4.1e-11 43.6 0.1 2.9 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGR32773.1 - 5.2e-10 38.9 0.0 1.9e-09 37.1 0.0 2.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGR32773.1 - 0.00013 21.8 0.9 0.00073 19.3 0.9 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HisG_C PF08029.11 EGR32773.1 - 0.08 13.1 0.0 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 HisG, C-terminal domain Pkinase_fungal PF17667.1 EGR32774.1 - 1.2e-05 24.2 0.0 1.5e-05 24.0 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EGR32774.1 - 0.0011 18.4 0.0 0.0012 18.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Cnd2 PF05786.14 EGR32775.1 - 9.7e-12 44.4 2.8 1.2e-11 44.1 2.8 1.0 1 0 0 1 1 1 1 Condensin complex subunit 2 SPRY PF00622.28 EGR32776.1 - 9.3e-12 45.1 0.1 1e-11 45.0 0.1 1.0 1 0 0 1 1 1 1 SPRY domain Elong_Iki1 PF10483.9 EGR32777.1 - 0.0014 18.2 1.6 0.0015 18.1 1.6 1.0 1 0 0 1 1 1 1 Elongator subunit Iki1 His_binding PF02098.16 EGR32777.1 - 0.86 9.6 7.9 1.1 9.3 7.9 1.2 1 0 0 1 1 1 0 Tick histamine binding protein GBP PF02263.19 EGR32778.1 - 4.5e-05 22.9 0.4 8.5e-05 21.9 0.0 1.6 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain ATPase_2 PF01637.18 EGR32778.1 - 0.00028 20.9 1.2 0.0029 17.5 0.0 2.0 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea FtsK_SpoIIIE PF01580.18 EGR32778.1 - 0.0041 16.5 0.0 0.007 15.7 0.0 1.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family MobB PF03205.14 EGR32778.1 - 0.02 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.23 EGR32778.1 - 0.03 14.4 0.2 0.077 13.1 0.1 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_14 PF13173.6 EGR32778.1 - 0.097 12.7 1.7 0.19 11.8 0.1 2.1 1 1 1 2 2 2 0 AAA domain Dynamin_N PF00350.23 EGR32778.1 - 0.75 9.8 0.0 0.75 9.8 0.0 2.3 2 1 0 2 2 2 0 Dynamin family ABC_tran PF00005.27 EGR32778.1 - 4.2 7.9 7.4 7.6 7.0 0.1 2.1 1 1 1 2 2 2 0 ABC transporter DUF4821 PF16092.5 EGR32779.1 - 1.2e-83 280.8 20.4 9.6e-83 277.8 4.8 3.5 4 0 0 4 4 4 2 Domain of unknown function (DUF4821) Pyr_redox_2 PF07992.14 EGR32779.1 - 0.00035 19.9 0.1 0.1 11.8 0.0 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGR32779.1 - 0.066 13.8 0.1 19 5.9 0.0 3.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Oxysterol_BP PF01237.18 EGR32781.1 - 3.3e-31 108.5 5.1 2.3e-29 102.4 0.1 3.3 2 2 1 3 3 3 2 Oxysterol-binding protein LptF_LptG PF03739.14 EGR32781.1 - 0.32 9.8 8.9 0.037 12.9 3.9 1.9 1 1 1 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG CENP-B_dimeris PF09026.10 EGR32781.1 - 1.3 9.4 6.8 2.7 8.4 6.8 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Thioredoxin PF00085.20 EGR32783.1 - 1.9e-58 194.8 9.0 1.5e-28 98.7 0.2 4.2 5 0 0 5 5 5 2 Thioredoxin Thioredoxin_6 PF13848.6 EGR32783.1 - 2e-16 60.5 30.7 7.8e-15 55.3 10.3 4.0 2 1 2 4 4 4 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EGR32783.1 - 1.6e-11 44.1 9.2 2.8e-06 26.9 0.3 3.8 2 2 1 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EGR32783.1 - 4.8e-11 42.7 0.3 0.00091 19.4 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EGR32783.1 - 7.2e-10 39.3 0.4 0.0012 19.3 0.0 3.7 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGR32783.1 - 1.5e-09 38.0 14.8 0.0043 17.3 0.0 6.6 5 2 2 7 7 7 3 Thioredoxin-like AhpC-TSA PF00578.21 EGR32783.1 - 2.3e-07 30.8 1.1 0.0015 18.5 0.1 3.2 3 0 0 3 3 3 2 AhpC/TSA family Redoxin PF08534.10 EGR32783.1 - 4.3e-05 23.3 0.4 0.51 10.0 0.0 3.3 3 0 0 3 3 3 2 Redoxin Thioredoxin_3 PF13192.6 EGR32783.1 - 0.0013 18.7 0.8 1 9.5 0.0 3.6 3 0 0 3 3 3 1 Thioredoxin domain DUF953 PF06110.11 EGR32783.1 - 0.027 14.1 1.8 5.1 6.7 0.0 4.2 4 1 0 4 4 4 0 Eukaryotic protein of unknown function (DUF953) PspB PF06667.12 EGR32783.1 - 0.18 11.9 1.4 21 5.2 0.0 2.7 2 0 0 2 2 2 0 Phage shock protein B tRNA_anti-like PF12869.7 EGR32783.1 - 1.3 8.7 6.1 0.13 11.9 0.4 2.4 3 0 0 3 3 3 0 tRNA_anti-like O-antigen_lig PF13425.6 EGR32783.1 - 2.7 6.7 11.4 2.5 6.8 3.0 2.4 2 0 0 2 2 2 0 O-antigen ligase like membrane protein CRM1_C PF08767.11 EGR32784.1 - 0.015 14.5 1.1 0.02 14.1 0.7 1.4 1 1 0 1 1 1 0 CRM1 C terminal DUF481 PF04338.12 EGR32785.1 - 0.2 11.7 1.3 1.1 9.3 0.6 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF481 E1_DerP2_DerF2 PF02221.15 EGR32785.1 - 5.2 7.5 16.2 6.2e+03 -2.5 16.2 2.6 1 1 0 1 1 1 0 ML domain Peptidase_C2 PF00648.21 EGR32787.1 - 2.6e-80 269.6 1.2 2.6e-80 269.6 1.2 2.3 3 0 0 3 3 3 1 Calpain family cysteine protease DUF5494 PF17598.2 EGR32787.1 - 0.071 13.2 2.6 0.18 11.9 2.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5494) Asp PF00026.23 EGR32788.1 - 3.5e-97 325.6 1.3 4.1e-97 325.4 1.3 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGR32788.1 - 1.2e-13 51.6 2.8 4.2e-12 46.7 1.2 2.5 2 1 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGR32788.1 - 5.9e-05 23.6 0.1 0.78 10.4 0.0 3.1 2 1 0 2 2 2 2 Aspartyl protease TAXi_C PF14541.6 EGR32788.1 - 0.00053 19.8 0.0 0.0033 17.2 0.0 2.2 1 1 0 1 1 1 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EGR32788.1 - 0.0042 17.6 0.0 6.7 7.3 0.0 3.0 3 1 0 3 3 3 2 gag-polyprotein putative aspartyl protease preSET_CXC PF18264.1 EGR32789.1 - 3.1e-06 27.5 15.1 3.1e-06 27.5 15.1 2.5 2 1 1 3 3 3 1 CXC domain TPR_2 PF07719.17 EGR32790.1 - 6.7e-36 119.5 25.9 0.015 15.4 0.1 15.2 15 0 0 15 15 15 9 Tetratricopeptide repeat TPR_1 PF00515.28 EGR32790.1 - 5.9e-30 101.9 52.7 0.0095 15.7 0.2 15.7 17 0 0 17 17 16 9 Tetratricopeptide repeat TPR_19 PF14559.6 EGR32790.1 - 1.8e-25 89.3 19.3 2.4e-05 24.7 3.9 9.8 7 3 5 12 12 12 7 Tetratricopeptide repeat TPR_11 PF13414.6 EGR32790.1 - 8.2e-20 70.2 40.7 0.032 13.9 0.6 12.7 11 2 2 13 13 12 6 TPR repeat TPR_12 PF13424.6 EGR32790.1 - 2.9e-18 65.9 9.4 0.0034 17.6 0.4 9.8 7 3 2 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGR32790.1 - 7.6e-18 64.9 0.0 1.8e-06 28.5 0.0 6.7 6 2 2 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR32790.1 - 2.4e-16 59.7 44.2 0.00019 21.6 0.8 10.8 7 3 6 13 13 13 9 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGR32790.1 - 5.2e-15 55.0 17.0 0.15 12.8 0.3 12.1 13 0 0 13 13 13 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGR32790.1 - 1.6e-13 49.7 52.9 0.13 12.5 0.1 14.2 15 0 0 15 15 15 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGR32790.1 - 1.6e-08 34.6 0.0 7.6 7.6 0.0 8.1 6 1 2 8 8 8 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGR32790.1 - 7.7e-08 32.4 0.0 2.4 8.3 0.0 7.4 6 3 2 8 8 8 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EGR32790.1 - 1.6e-05 24.5 0.0 2.6 7.7 0.0 5.8 5 2 1 7 7 7 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_MalT PF17874.1 EGR32790.1 - 2.4e-05 23.9 0.8 1.5 8.1 0.0 4.5 2 1 3 5 5 5 2 MalT-like TPR region TPR_17 PF13431.6 EGR32790.1 - 7.1e-05 22.9 19.9 8.4 7.0 0.5 10.5 10 1 1 11 11 11 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGR32790.1 - 0.017 15.2 5.9 5.5 7.2 0.0 5.1 4 0 0 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EGR32790.1 - 0.017 15.6 0.3 0.08 13.4 0.3 2.2 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation TPR_20 PF14561.6 EGR32790.1 - 0.058 13.7 5.1 0.86 10.0 0.4 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGR32790.1 - 0.19 11.2 7.3 6.2 6.4 0.0 6.1 7 0 0 7 7 7 0 SHNi-TPR RPN7 PF10602.9 EGR32790.1 - 0.86 9.3 26.6 0.069 12.8 2.3 6.7 3 2 2 5 5 5 0 26S proteasome subunit RPN7 ERGIC_N PF13850.6 EGR32791.1 - 0.00089 19.6 5.3 0.0086 16.4 0.1 3.7 3 1 0 3 3 3 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) DEAD PF00270.29 EGR32792.1 - 9.8e-50 168.7 0.9 2.7e-49 167.3 0.0 2.3 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR32792.1 - 2.1e-35 121.4 1.0 2.2e-33 114.9 0.2 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain PIP49_C PF12260.8 EGR32792.1 - 0.0021 17.7 3.1 0.021 14.5 0.6 2.7 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 WD40 PF00400.32 EGR32793.1 - 1.9e-32 110.8 0.6 8.9e-05 23.2 0.0 6.5 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR32793.1 - 3.7e-10 40.0 0.2 5.6e-05 23.4 0.0 4.3 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGR32793.1 - 1.6e-06 27.7 0.1 0.00042 19.8 0.2 2.5 1 1 1 2 2 2 2 WD40-like domain eIF2A PF08662.11 EGR32793.1 - 0.00053 19.9 1.4 0.022 14.6 0.1 2.1 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Cytochrom_D1 PF02239.16 EGR32793.1 - 0.0016 17.0 0.0 0.39 9.2 0.0 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain Ig_2 PF13895.6 EGR32793.1 - 0.15 12.4 0.9 2.9 8.3 0.5 2.5 1 1 1 2 2 2 0 Immunoglobulin domain HMMR_N PF15905.5 EGR32794.1 - 0.058 12.9 7.5 0.064 12.7 7.5 1.0 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal TPR_12 PF13424.6 EGR32795.1 - 6.8e-28 96.8 3.1 9.6e-11 41.8 0.1 3.2 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 EGR32795.1 - 1.6e-09 37.3 0.0 0.14 12.1 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGR32795.1 - 1.6e-07 30.8 15.3 0.0025 17.6 3.1 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGR32795.1 - 5.9e-07 29.1 9.8 1.2 9.4 0.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGR32795.1 - 9.9e-06 25.4 21.1 0.027 14.7 0.3 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGR32795.1 - 0.00038 20.1 1.9 8.7 6.1 0.1 4.6 4 0 0 4 4 4 1 TPR repeat TPR_MalT PF17874.1 EGR32795.1 - 0.029 13.8 0.3 3.7 6.8 0.0 2.1 2 0 0 2 2 2 0 MalT-like TPR region TPR_17 PF13431.6 EGR32795.1 - 0.23 11.9 3.9 88 3.8 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat Pkinase PF00069.25 EGR32796.1 - 1.5e-19 70.4 7.4 2e-16 60.2 0.0 3.0 3 1 1 4 4 4 2 Protein kinase domain PHM7_cyt PF14703.6 EGR32796.1 - 1.2e-18 68.0 10.2 3.4e-18 66.5 10.2 1.8 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Pkinase_Tyr PF07714.17 EGR32796.1 - 1.1e-11 44.5 0.1 6.2e-10 38.8 0.0 2.5 1 1 1 2 2 2 1 Protein tyrosine kinase Anoctamin PF04547.12 EGR32796.1 - 0.13 11.0 31.3 0.0088 14.9 25.0 2.1 2 1 0 2 2 2 0 Calcium-activated chloride channel CortBP2 PF09727.9 EGR32796.1 - 3.4 7.5 11.7 0.15 12.0 5.1 2.0 2 0 0 2 2 2 0 Cortactin-binding protein-2 RmuC PF02646.16 EGR32797.1 - 0.00016 20.9 1.4 0.00016 20.9 1.4 1.9 1 1 1 2 2 2 1 RmuC family EzrA PF06160.12 EGR32797.1 - 0.0021 16.3 5.3 0.0027 16.0 5.3 1.1 1 0 0 1 1 1 1 Septation ring formation regulator, EzrA GAS PF13851.6 EGR32797.1 - 0.0021 17.5 5.9 0.0029 17.0 5.9 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 EGR32797.1 - 0.0023 18.0 3.5 0.0027 17.7 3.5 1.1 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 EGR32797.1 - 0.0025 17.9 7.8 0.0039 17.2 7.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1664) NBP1 PF08537.10 EGR32797.1 - 0.003 17.0 3.7 0.0036 16.8 3.7 1.1 1 0 0 1 1 1 1 Fungal Nap binding protein NBP1 Apolipoprotein PF01442.18 EGR32797.1 - 0.0032 17.3 1.3 0.0056 16.6 1.3 1.3 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF2095 PF09868.9 EGR32797.1 - 0.0036 17.3 0.2 0.0041 17.1 0.2 1.1 1 0 0 1 1 1 1 Uncharacterized protein conserved in archaea (DUF2095) Cytochrom_B562 PF07361.11 EGR32797.1 - 0.0039 17.8 7.8 0.008 16.8 7.8 1.5 1 1 0 1 1 1 1 Cytochrome b562 BAR_3 PF16746.5 EGR32797.1 - 0.0051 16.5 4.9 0.0061 16.3 4.9 1.1 1 0 0 1 1 1 1 BAR domain of APPL family 4HFCP_synth PF04476.13 EGR32797.1 - 0.0055 16.4 0.2 0.0077 16.0 0.2 1.3 1 1 0 1 1 1 1 4-HFC-P synthase GrpE PF01025.19 EGR32797.1 - 0.0059 16.3 3.4 0.0067 16.1 3.4 1.1 1 0 0 1 1 1 1 GrpE Rab5-bind PF09311.11 EGR32797.1 - 0.0059 16.0 5.9 0.0069 15.8 5.9 1.0 1 0 0 1 1 1 1 Rabaptin-like protein Ribosomal_L1 PF00687.21 EGR32797.1 - 0.0072 16.1 2.2 0.0082 15.9 2.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family WEMBL PF05701.11 EGR32797.1 - 0.0076 15.0 2.2 0.0082 14.9 2.2 1.0 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Prominin PF05478.11 EGR32797.1 - 0.0078 14.2 4.6 0.01 13.8 4.6 1.2 1 0 0 1 1 1 1 Prominin DUF3584 PF12128.8 EGR32797.1 - 0.0088 13.6 2.8 0.0095 13.5 2.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Latarcin PF10279.9 EGR32797.1 - 0.0093 16.3 3.7 0.41 11.1 2.3 2.1 1 1 1 2 2 2 1 Latarcin precursor DUF4559 PF15112.6 EGR32797.1 - 0.011 15.5 6.3 0.013 15.2 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) HMMR_N PF15905.5 EGR32797.1 - 0.011 15.2 7.3 0.013 15.0 7.3 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal SesA PF17107.5 EGR32797.1 - 0.014 15.6 1.6 0.13 12.4 0.2 2.0 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Syntaxin-6_N PF09177.11 EGR32797.1 - 0.014 15.9 1.9 0.024 15.2 1.9 1.4 1 1 0 1 1 1 0 Syntaxin 6, N-terminal DUF948 PF06103.11 EGR32797.1 - 0.018 15.3 7.6 0.04 14.2 7.7 1.6 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) MCPsignal PF00015.21 EGR32797.1 - 0.023 14.5 5.9 0.027 14.3 5.9 1.1 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Cytochrom_C_2 PF01322.20 EGR32797.1 - 0.024 15.5 2.9 0.039 14.8 2.9 1.4 1 1 0 1 1 1 0 Cytochrome C' Filament PF00038.21 EGR32797.1 - 0.025 14.2 5.1 0.033 13.8 5.1 1.1 1 0 0 1 1 1 0 Intermediate filament protein DUF4201 PF13870.6 EGR32797.1 - 0.026 14.3 8.0 0.056 13.2 7.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) DUF745 PF05335.13 EGR32797.1 - 0.03 14.1 3.0 0.035 13.8 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) ISG65-75 PF11727.8 EGR32797.1 - 0.03 13.6 4.5 0.034 13.4 4.5 1.0 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF1729 PF08354.10 EGR32797.1 - 0.03 13.2 0.5 0.035 13.0 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) HemX PF04375.14 EGR32797.1 - 0.031 13.6 4.5 0.037 13.3 4.5 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase ApoLp-III PF07464.11 EGR32797.1 - 0.032 14.3 10.0 0.069 13.3 10.0 1.5 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) T3SSipB PF16535.5 EGR32797.1 - 0.032 14.7 3.8 0.043 14.3 3.8 1.1 1 0 0 1 1 1 0 Type III cell invasion protein SipB Sec34 PF04136.15 EGR32797.1 - 0.033 14.1 5.2 0.031 14.2 3.5 1.7 1 1 1 2 2 2 0 Sec34-like family APG17 PF04108.12 EGR32797.1 - 0.034 13.3 3.5 0.04 13.0 3.5 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 CALCOCO1 PF07888.11 EGR32797.1 - 0.036 13.0 4.1 0.043 12.7 4.1 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like COG2 PF06148.11 EGR32797.1 - 0.04 14.0 4.8 0.19 11.8 0.5 1.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 YtxH PF12732.7 EGR32797.1 - 0.043 14.4 5.1 0.39 11.3 5.1 2.1 1 1 0 1 1 1 0 YtxH-like protein WXG100 PF06013.12 EGR32797.1 - 0.043 14.1 5.5 0.79 10.0 5.2 2.6 1 1 1 2 2 2 0 Proteins of 100 residues with WXG TMPIT PF07851.13 EGR32797.1 - 0.054 12.7 5.9 0.069 12.4 5.9 1.2 1 0 0 1 1 1 0 TMPIT-like protein PCRF PF03462.18 EGR32797.1 - 0.062 13.2 2.9 0.076 12.9 2.9 1.1 1 0 0 1 1 1 0 PCRF domain DUF5344 PF17279.2 EGR32797.1 - 0.063 13.9 8.5 1 10.0 8.4 2.3 1 1 0 1 1 1 0 Family of unknown function (DUF5344) Bul1_C PF04426.12 EGR32797.1 - 0.072 12.5 5.1 0.094 12.1 0.9 2.0 1 1 1 2 2 2 0 Bul1 C terminus Phage_GP20 PF06810.11 EGR32797.1 - 0.075 12.8 12.4 0.11 12.3 4.9 2.0 1 1 1 2 2 2 0 Phage minor structural protein GP20 KELK PF15796.5 EGR32797.1 - 0.084 13.3 6.0 1.7 9.2 2.6 2.3 1 1 1 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase PHA_synth_III_E PF09712.10 EGR32797.1 - 0.09 11.8 3.0 0.1 11.7 3.0 1.1 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) DUF148 PF02520.17 EGR32797.1 - 0.093 12.8 11.0 0.23 11.6 11.0 1.5 1 1 0 1 1 1 0 Domain of unknown function DUF148 Laminin_II PF06009.12 EGR32797.1 - 0.096 12.7 6.9 0.052 13.6 1.5 1.8 1 1 1 2 2 2 0 Laminin Domain II Spc7 PF08317.11 EGR32797.1 - 0.098 11.5 7.6 0.17 10.8 7.7 1.3 1 1 0 1 1 1 0 Spc7 kinetochore protein AI-2E_transport PF01594.16 EGR32797.1 - 0.098 11.8 0.8 0.11 11.7 0.8 1.1 1 0 0 1 1 1 0 AI-2E family transporter Corona_S2 PF01601.16 EGR32797.1 - 0.11 11.0 4.2 0.13 10.7 4.2 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein NPV_P10 PF05531.12 EGR32797.1 - 0.13 12.8 7.8 1.5 9.4 7.7 2.2 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein MscS_porin PF12795.7 EGR32797.1 - 0.14 11.7 5.4 0.47 10.0 0.4 1.9 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain FlaC_arch PF05377.11 EGR32797.1 - 0.16 12.4 10.9 0.82 10.1 0.4 2.5 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) REV1_C PF16727.5 EGR32797.1 - 0.21 12.0 2.1 0.32 11.4 2.1 1.4 1 1 0 1 1 1 0 DNA repair protein REV1 C-terminal domain USP8_interact PF08941.10 EGR32797.1 - 0.24 11.2 6.2 0.41 10.4 6.2 1.4 1 1 0 1 1 1 0 USP8 interacting Fib_alpha PF08702.10 EGR32797.1 - 0.27 11.4 11.2 0.099 12.8 2.7 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Prefoldin_2 PF01920.20 EGR32797.1 - 0.27 11.2 12.2 10 6.1 12.2 2.1 1 1 0 1 1 1 0 Prefoldin subunit Z1 PF10593.9 EGR32797.1 - 0.28 10.7 4.3 0.37 10.2 4.3 1.1 1 0 0 1 1 1 0 Z1 domain BORCS8 PF10167.9 EGR32797.1 - 0.39 10.7 6.3 1.5 8.8 2.5 2.2 1 1 1 2 2 2 0 BLOC-1-related complex sub-unit 8 YabA PF06156.13 EGR32797.1 - 0.4 11.3 7.0 2.7 8.7 0.2 2.0 1 1 1 2 2 2 0 Initiation control protein YabA YojJ PF10372.9 EGR32797.1 - 0.4 10.8 6.7 2.3 8.4 0.2 2.3 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus DUF5082 PF16888.5 EGR32797.1 - 0.43 10.9 12.2 6.7 7.0 12.2 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF5082) UPF0242 PF06785.11 EGR32797.1 - 0.54 10.3 8.1 0.74 9.9 8.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus Tup_N PF08581.10 EGR32797.1 - 0.69 10.3 11.4 4.7 7.6 4.2 2.3 1 1 1 2 2 2 0 Tup N-terminal Snapin_Pallidin PF14712.6 EGR32797.1 - 0.69 10.4 7.9 1.1 9.8 5.1 2.0 1 1 1 2 2 2 0 Snapin/Pallidin Prefoldin PF02996.17 EGR32797.1 - 0.7 9.8 8.7 1.2 9.0 1.1 2.2 1 1 1 2 2 2 0 Prefoldin subunit Mis14 PF08641.12 EGR32797.1 - 0.86 9.9 8.1 1.9 8.8 4.2 2.0 1 1 1 2 2 2 0 Kinetochore protein Mis14 like PRKG1_interact PF15898.5 EGR32797.1 - 1 10.3 6.1 17 6.4 6.1 2.3 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF4446 PF14584.6 EGR32797.1 - 1 9.3 7.4 4 7.4 6.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) Fzo_mitofusin PF04799.13 EGR32797.1 - 1.1 8.8 6.4 1.4 8.4 0.6 2.0 1 1 1 2 2 2 0 fzo-like conserved region LMBR1 PF04791.16 EGR32797.1 - 1.2 8.0 2.8 1.3 7.8 2.8 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein LPP PF04728.13 EGR32797.1 - 1.5 9.3 6.2 1.2 9.6 0.2 2.5 2 1 0 2 2 2 0 Lipoprotein leucine-zipper ABC_tran_Xtn PF12848.7 EGR32797.1 - 2.1 8.5 9.2 1.5 8.9 4.5 2.1 1 1 0 2 2 2 0 ABC transporter SlyX PF04102.12 EGR32797.1 - 2.8 8.6 7.1 29 5.3 3.9 2.3 1 1 1 2 2 2 0 SlyX AKNA PF12443.8 EGR32797.1 - 3.8 8.2 6.8 39 5.0 6.8 2.3 1 1 0 1 1 1 0 AT-hook-containing transcription factor Mito_carr PF00153.27 EGR32799.1 - 1.1e-55 185.5 3.0 1.3e-20 73.1 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4885 PF16226.5 EGR32799.1 - 0.056 12.5 0.4 0.08 12.0 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4885) UPF0715 PF17094.5 EGR32799.1 - 5.1 7.7 9.4 0.51 10.9 0.6 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0715) IF4E PF01652.18 EGR32800.1 - 1.7e-16 60.4 4.1 2.6e-16 59.8 4.1 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E GMP_PDE_delta PF05351.11 EGR32801.1 - 1.9e-63 213.3 10.5 2.2e-63 213.0 10.5 1.1 1 0 0 1 1 1 1 GMP-PDE, delta subunit EF-hand_7 PF13499.6 EGR32802.1 - 2.3e-31 108.0 56.3 7e-07 29.6 2.5 10.7 10 2 1 11 11 10 9 EF-hand domain pair EF-hand_6 PF13405.6 EGR32802.1 - 3.2e-27 92.1 59.3 1.4e-05 24.7 1.0 13.2 12 0 0 12 12 12 9 EF-hand domain HU-CCDC81_euk_1 PF14908.6 EGR32802.1 - 1.7e-26 92.2 0.4 9.3e-26 89.8 0.0 2.5 2 0 0 2 2 2 1 CCDC81 eukaryotic HU domain 1 EF-hand_1 PF00036.32 EGR32802.1 - 2e-24 83.3 61.9 5.1e-05 22.5 0.3 12.5 12 0 0 12 12 12 8 EF hand HU-CCDC81_euk_2 PF18289.1 EGR32802.1 - 1.5e-17 63.5 0.7 1.1e-16 60.7 0.1 2.8 3 0 0 3 3 3 1 CCDC81 eukaryotic HU domain 2 EF-hand_8 PF13833.6 EGR32802.1 - 1.5e-15 56.8 45.1 5.8e-06 26.1 0.1 11.9 11 2 2 13 13 13 7 EF-hand domain pair EF-hand_5 PF13202.6 EGR32802.1 - 1.1e-11 43.7 39.0 1e-05 24.8 1.6 7.4 6 0 0 6 6 6 4 EF hand EF-hand_9 PF14658.6 EGR32802.1 - 3.9e-06 27.1 1.9 19 5.6 0.0 7.3 7 1 0 7 7 6 0 EF-hand domain EF-hand_11 PF08976.11 EGR32802.1 - 0.0003 21.6 13.1 0.00066 20.5 0.1 5.5 6 0 0 6 6 6 1 EF-hand domain Bac_DNA_binding PF00216.21 EGR32802.1 - 0.0025 18.0 7.0 5.1 7.4 0.0 5.3 5 1 1 6 6 6 1 Bacterial DNA-binding protein RRF_GI PF12614.8 EGR32802.1 - 0.0064 16.6 0.4 0.053 13.7 0.4 2.6 1 0 0 1 1 1 1 Ribosome recycling factor DUF4313 PF14190.6 EGR32802.1 - 0.0071 16.3 4.0 0.015 15.2 0.2 3.7 3 1 1 4 4 3 1 Domain of unknown function (DUF4313) Ras_bdg_2 PF14847.6 EGR32802.1 - 0.0081 16.5 0.2 0.05 13.9 0.2 2.4 1 0 0 1 1 1 1 Ras-binding domain of Byr2 HU-HIG PF18291.1 EGR32802.1 - 0.045 13.9 0.0 0.43 10.7 0.0 2.6 3 0 0 3 3 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif Nse4-Nse3_bdg PF15412.6 EGR32802.1 - 0.099 12.8 4.4 0.77 9.9 0.6 4.0 3 1 1 4 4 4 0 Binding domain of Nse4/EID3 to Nse3-MAGE SPARC_Ca_bdg PF10591.9 EGR32802.1 - 0.24 11.7 19.9 6.3 7.2 0.0 7.4 6 2 0 7 7 6 0 Secreted protein acidic and rich in cysteine Ca binding region Myelin_PLP PF01275.19 EGR32802.1 - 1.4 8.7 4.8 1.8 8.4 2.1 2.1 2 0 0 2 2 2 0 Myelin proteolipid protein (PLP or lipophilin) EF-hand_13 PF17958.1 EGR32802.1 - 5.3 6.9 8.9 28 4.6 0.0 5.8 7 0 0 7 7 7 0 EF-hand domain DHHC PF01529.20 EGR32804.1 - 5e-36 123.8 13.6 5e-36 123.8 13.6 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase FGGY_N PF00370.21 EGR32804.1 - 0.015 14.9 0.0 0.021 14.4 0.0 1.2 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, N-terminal domain Baculo_11_kDa PF06143.11 EGR32804.1 - 0.022 14.3 1.3 0.022 14.3 1.3 3.5 3 1 1 4 4 4 0 Baculovirus 11 kDa family Spt4 PF06093.13 EGR32804.1 - 0.45 10.6 4.7 0.83 9.8 4.7 1.4 1 0 0 1 1 1 0 Spt4/RpoE2 zinc finger LRR_6 PF13516.6 EGR32805.1 - 1.6e-07 30.8 105.7 0.046 13.8 0.1 21.3 23 0 0 23 23 23 12 Leucine Rich repeat LRR_4 PF12799.7 EGR32805.1 - 2.3e-05 24.6 134.5 0.004 17.5 0.8 18.1 9 4 10 19 19 19 10 Leucine Rich repeats (2 copies) SUIM_assoc PF16619.5 EGR32805.1 - 1.8 8.7 7.2 0.33 11.0 1.8 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Metallophos PF00149.28 EGR32806.1 - 1.4e-40 140.0 0.1 1.7e-40 139.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGR32806.1 - 1.4e-19 70.3 2.1 1.8e-18 66.7 1.1 2.3 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain Mito_carr PF00153.27 EGR32807.1 - 2.2e-16 59.6 0.6 1e-09 38.2 0.1 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein BTP PF05232.12 EGR32807.1 - 1.9 8.6 8.5 0.35 11.0 2.2 2.2 2 0 0 2 2 2 0 Chlorhexidine efflux transporter CN_hydrolase PF00795.22 EGR32808.1 - 9.9e-46 156.2 0.0 1.1e-45 156.0 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase CHASE7 PF17151.4 EGR32811.1 - 0.043 13.4 1.2 0.91 9.1 0.0 2.8 3 1 0 3 3 3 0 Periplasmic sensor domain Diphthamide_syn PF01866.17 EGR32812.1 - 7e-34 117.6 4.1 1.1e-33 117.0 4.1 1.3 1 0 0 1 1 1 1 Putative diphthamide synthesis protein Glyco_hydro_59 PF02057.15 EGR32812.1 - 0.079 12.2 0.1 0.09 12.0 0.1 1.4 1 1 0 1 1 1 0 Glycosyl hydrolase family 59 ACOX PF01756.19 EGR32813.1 - 7.5e-41 139.7 0.1 1.4e-40 138.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EGR32813.1 - 4.8e-13 49.1 0.0 7.8e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EGR32813.1 - 2.3e-09 37.6 0.0 8.3e-09 35.8 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ASPRs PF17641.2 EGR32813.1 - 0.015 15.6 0.2 0.06 13.6 0.2 1.9 1 1 0 1 1 1 0 Ancylostoma-associated secreted protein related Ribosomal_L16 PF00252.18 EGR32814.1 - 1.6e-35 122.0 0.3 2e-35 121.6 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e Fibritin_C PF07921.12 EGR32815.1 - 0.0093 16.1 0.0 0.035 14.2 0.0 1.9 2 0 0 2 2 2 1 Fibritin C-terminal region SET PF00856.28 EGR32816.1 - 0.2 12.0 1.4 0.51 10.7 1.4 1.8 1 1 0 1 1 1 0 SET domain Pro_CA PF00484.19 EGR32817.1 - 6.3e-49 166.3 0.3 8.7e-49 165.8 0.3 1.2 1 0 0 1 1 1 1 Carbonic anhydrase DUF1722 PF08349.11 EGR32817.1 - 0.037 14.3 0.1 0.088 13.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Peptidase_C2 PF00648.21 EGR32820.1 - 2.3e-11 43.3 0.6 6.6e-10 38.5 0.6 2.0 1 1 0 1 1 1 1 Calpain family cysteine protease PX PF00787.24 EGR32824.1 - 4.7e-07 29.8 0.1 4.7e-07 29.8 0.1 3.0 3 1 1 4 4 4 1 PX domain cobW PF02492.19 EGR32824.1 - 0.075 12.6 2.6 0.078 12.6 1.0 1.9 2 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain LRR_4 PF12799.7 EGR32825.1 - 1.2e-12 47.8 22.3 2.6e-06 27.7 1.0 4.5 3 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGR32825.1 - 1.3e-08 34.5 15.3 0.0068 16.1 0.4 3.6 2 1 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 EGR32825.1 - 1.3e-06 28.0 8.4 2.4e-05 23.9 8.9 2.5 1 1 1 2 2 2 2 Leucine-rich repeat RRN9 PF10680.9 EGR32825.1 - 0.89 9.9 3.2 1.9 8.8 3.2 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor Vps39_2 PF10367.9 EGR32826.1 - 2.4e-16 60.1 0.3 2.4e-16 60.1 0.3 4.0 4 0 0 4 4 4 1 Vacuolar sorting protein 39 domain 2 FTCD_C PF04961.12 EGR32826.1 - 0.0095 15.7 0.9 0.025 14.4 0.9 1.6 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase DUF5101 PF17031.5 EGR32826.1 - 0.019 15.1 3.0 0.019 15.1 3.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF5101) EF-hand_4 PF12763.7 EGR32826.1 - 0.083 12.9 2.5 0.19 11.7 0.3 2.8 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand TPP1 PF10341.9 EGR32826.1 - 5.8 6.9 9.0 1.7 8.6 0.2 4.0 2 1 0 2 2 2 0 Shelterin complex subunit, TPP1/ACD Prenyltrans PF00432.21 EGR32827.1 - 5.7e-28 96.4 1.4 1.2e-09 37.7 0.0 4.2 4 0 0 4 4 4 4 Prenyltransferase and squalene oxidase repeat Phage_rep_org_N PF09681.10 EGR32827.1 - 0.097 12.6 0.1 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) SQHop_cyclase_N PF13249.6 EGR32827.1 - 0.2 10.7 0.0 0.62 9.1 0.0 1.7 2 0 0 2 2 2 0 Squalene-hopene cyclase N-terminal domain Ank_2 PF12796.7 EGR32828.1 - 8e-14 52.0 0.0 1.9e-05 25.1 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGR32828.1 - 2.8e-13 50.1 0.1 1.6e-07 31.7 0.0 3.1 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGR32828.1 - 4.5e-13 49.1 0.3 1.3e-05 25.4 0.1 3.1 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR32828.1 - 1.4e-11 43.5 0.6 0.012 16.0 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 EGR32828.1 - 1.6e-06 28.3 0.1 0.18 12.3 0.1 3.8 4 1 0 4 4 4 2 Ankyrin repeat CENP-T_C PF15511.6 EGR32831.1 - 1.4e-09 38.0 0.2 1.7e-09 37.7 0.2 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Histone PF00125.24 EGR32831.1 - 9.3e-05 22.8 0.6 0.00015 22.1 0.7 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF PF02969.17 EGR32831.1 - 0.00019 21.5 0.2 0.00028 21.0 0.2 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CBFD_NFYB_HMF PF00808.23 EGR32831.1 - 0.00023 21.4 0.1 0.00037 20.7 0.1 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-S PF15630.6 EGR32831.1 - 0.00026 21.3 0.3 0.00036 20.8 0.3 1.4 1 1 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.13 EGR32831.1 - 0.00082 19.3 0.1 0.0015 18.5 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 EGR32831.1 - 0.0043 17.1 0.0 0.0048 17.0 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Ribosomal_L27A PF00828.19 EGR32831.1 - 0.028 15.1 3.0 0.035 14.8 3.0 1.3 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A TAF4 PF05236.14 EGR32831.1 - 0.077 12.7 0.1 0.089 12.5 0.1 1.0 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family DUF364 PF04016.12 EGR32831.1 - 0.089 12.4 0.0 0.12 11.9 0.0 1.3 1 1 0 1 1 1 0 Putative heavy-metal chelation Histone PF00125.24 EGR32832.1 - 2.4e-51 173.5 2.8 3.3e-51 173.1 2.8 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 EGR32832.1 - 0.0002 22.0 2.2 0.00035 21.2 2.2 1.4 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EGR32832.1 - 0.00065 19.8 0.1 0.00065 19.8 0.1 1.8 2 1 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGR32832.1 - 0.0017 18.7 1.6 0.002 18.4 0.0 1.8 2 0 0 2 2 2 1 CENP-S protein TFIID-31kDa PF02291.15 EGR32832.1 - 0.057 13.5 0.7 0.12 12.5 0.1 1.7 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit TMA7 PF09072.10 EGR32832.1 - 0.17 12.7 9.3 0.32 11.9 9.3 1.5 1 0 0 1 1 1 0 Translation machinery associated TMA7 Aminotran_1_2 PF00155.21 EGR32833.1 - 1.5e-70 238.2 0.1 1.9e-70 237.9 0.1 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DUF3069 PF11269.8 EGR32834.1 - 0.78 10.0 7.6 0.2 11.9 1.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3069) tRNA-synt_1c PF00749.21 EGR32835.1 - 1.1e-94 316.9 0.4 1.1e-94 316.9 0.4 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain Asparaginase PF00710.20 EGR32836.1 - 5.8e-48 163.0 0.0 1e-47 162.2 0.0 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Ank_2 PF12796.7 EGR32836.1 - 1.2e-16 61.1 0.7 4.5e-07 30.4 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Asparaginase_C PF17763.1 EGR32836.1 - 2.3e-14 53.6 0.0 3.8e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_4 PF13637.6 EGR32836.1 - 7.3e-14 51.9 0.4 5.9e-07 29.9 0.0 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR32836.1 - 9.2e-09 34.9 0.1 0.073 13.7 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EGR32836.1 - 4e-08 33.4 0.3 0.27 11.7 0.0 5.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EGR32836.1 - 6.2e-08 32.8 0.1 0.011 16.0 0.0 4.6 4 1 1 5 5 5 2 Ankyrin repeats (many copies) Rho_Binding PF08912.11 EGR32837.1 - 0.22 12.4 2.1 14 6.5 0.1 2.3 2 0 0 2 2 2 0 Rho Binding Gaa1 PF04114.14 EGR32838.1 - 1.6e-16 60.5 8.8 2.1e-16 60.1 8.8 1.1 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component PhoLip_ATPase_C PF16212.5 EGR32840.1 - 4.4e-59 200.2 31.7 4.4e-59 200.2 31.7 2.8 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EGR32840.1 - 1.1e-10 42.2 0.0 4.5e-07 30.4 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGR32840.1 - 5.9e-07 29.5 2.4 1.1e-05 25.4 0.1 3.3 3 0 0 3 3 3 1 Cation transport ATPase (P-type) PhoLip_ATPase_N PF16209.5 EGR32841.1 - 1.4e-19 69.5 4.0 1.4e-19 69.5 4.0 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EGR32841.1 - 0.00047 19.7 0.0 0.0011 18.5 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Saf_2TM PF18303.1 EGR32841.1 - 0.0022 17.6 1.9 0.0034 17.0 0.6 2.0 2 0 0 2 2 2 1 SAVED-fused 2TM effector domain Ephrin_rec_like PF07699.13 EGR32842.1 - 4e-05 23.3 53.1 0.023 14.5 9.5 7.9 2 2 6 8 8 8 4 Putative ephrin-receptor like Antistasin PF02822.14 EGR32842.1 - 3.9 8.2 18.9 30 5.4 0.0 6.6 8 0 0 8 8 8 0 Antistasin family Ephrin_rec_like PF07699.13 EGR32843.1 - 6e-05 22.7 54.0 0.018 14.8 9.2 8.0 2 2 6 8 8 8 4 Putative ephrin-receptor like Antistasin PF02822.14 EGR32843.1 - 3.3 8.4 18.6 32 5.3 0.0 6.7 8 0 0 8 8 8 0 Antistasin family Antistasin PF02822.14 EGR32844.1 - 9.5e-05 22.9 5.0 9.4 7.0 0.0 6.0 5 0 0 5 5 5 3 Antistasin family Ephrin_rec_like PF07699.13 EGR32844.1 - 0.7 9.7 40.3 0.08 12.7 0.7 6.9 5 1 2 7 7 7 0 Putative ephrin-receptor like Ephrin_rec_like PF07699.13 EGR32845.1 - 9.4e-14 50.9 88.4 9.7e-05 22.1 2.9 9.5 5 4 4 9 9 9 6 Putative ephrin-receptor like Antistasin PF02822.14 EGR32845.1 - 3e-05 24.5 1.8 46 4.8 0.0 7.2 6 0 0 6 6 6 1 Antistasin family zf-LYAR PF08790.11 EGR32845.1 - 9.5 6.2 19.2 5.5 7.0 0.1 6.6 7 0 0 7 7 7 0 LYAR-type C2HC zinc finger Peptidase_M8 PF01457.16 EGR32846.1 - 3.8e-17 62.2 3.8 1.2e-14 53.9 0.2 2.1 1 1 1 2 2 2 2 Leishmanolysin EF-hand_1 PF00036.32 EGR32848.1 - 1e-25 87.3 14.0 4.4e-07 29.0 0.3 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGR32848.1 - 7.1e-23 80.8 7.7 2e-12 47.4 0.8 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR32848.1 - 3e-22 76.6 8.8 8.6e-06 25.3 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGR32848.1 - 5.8e-22 76.2 11.1 4e-05 22.9 0.2 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGR32848.1 - 2.6e-13 49.6 8.8 0.0062 16.4 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGR32848.1 - 2.1e-07 31.2 0.1 0.029 14.7 0.0 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 EGR32848.1 - 0.00029 20.8 2.3 0.23 11.4 0.0 3.6 1 1 3 4 4 4 1 Caleosin related protein EF-hand_4 PF12763.7 EGR32848.1 - 0.0011 18.8 8.2 0.87 9.6 0.4 3.9 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EGR32848.1 - 0.0073 16.6 0.1 0.31 11.4 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain WD40 PF00400.32 EGR32849.1 - 3.2e-18 65.8 13.8 0.00097 19.9 0.7 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR32849.1 - 4.2e-05 23.7 2.3 0.56 10.5 0.1 4.6 2 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain CHAP PF05257.16 EGR32849.1 - 0.0089 16.6 1.6 0.6 10.7 0.0 3.3 2 1 1 3 3 3 1 CHAP domain NAP PF00956.18 EGR32850.1 - 1.4e-55 188.4 15.5 2.3e-55 187.7 15.5 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) GP46 PF07409.12 EGR32850.1 - 0.19 11.5 1.4 0.3 10.9 0.3 1.8 2 0 0 2 2 2 0 Phage protein GP46 TIM PF00121.18 EGR32851.1 - 6.2e-92 307.4 4.6 7.1e-92 307.2 4.6 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase AMPK1_CBM PF16561.5 EGR32851.1 - 0.0027 17.9 0.6 0.0065 16.7 0.6 1.6 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase XPG_I PF00867.18 EGR32852.1 - 2.7e-28 98.1 1.3 6.2e-28 97.0 0.1 2.2 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 EGR32852.1 - 7.1e-24 84.2 0.0 1.8e-23 82.9 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain 5_3_exonuc PF01367.20 EGR32852.1 - 1.6e-05 25.4 0.4 4.1e-05 24.1 0.0 1.9 2 0 0 2 2 2 1 5'-3' exonuclease, C-terminal SAM fold tRNA-synt_2 PF00152.20 EGR32853.1 - 3.1e-71 240.1 0.3 3.1e-71 240.1 0.3 1.9 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) Eapp_C PF10238.9 EGR32853.1 - 0.72 9.9 15.2 0.75 9.9 2.1 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF4820 PF16091.5 EGR32853.1 - 0.91 8.8 20.7 0.14 11.5 5.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF4228 PF14009.6 EGR32853.1 - 1.5 9.1 10.4 0.29 11.5 0.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) MDM31_MDM32 PF08118.11 EGR32853.1 - 6 5.4 17.5 0.065 11.9 5.8 2.2 2 0 0 2 2 2 0 Yeast mitochondrial distribution and morphology (MDM) proteins Vfa1 PF08432.10 EGR32853.1 - 6.5 7.0 28.1 3 8.2 7.5 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Gti1_Pac2 PF09729.9 EGR32853.1 - 8.9 6.4 17.2 4.6 7.3 2.4 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family Pkinase PF00069.25 EGR32854.1 - 1.1e-70 238.1 1.1 1.1e-70 238.1 1.1 2.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32854.1 - 2.8e-37 128.4 0.2 2.8e-37 128.4 0.2 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR32854.1 - 0.0015 17.4 8.1 0.21 10.3 6.8 2.5 2 0 0 2 2 2 2 Fungal protein kinase TFIIA PF03153.13 EGR32854.1 - 0.027 14.5 48.2 0.042 13.8 48.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 EGR32854.1 - 0.56 8.4 19.0 0.86 7.8 19.0 1.2 1 0 0 1 1 1 0 CDC45-like protein LAP1C PF05609.12 EGR32854.1 - 0.82 8.7 24.8 1.3 8.0 24.8 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) APH PF01636.23 EGR32854.1 - 0.93 9.4 4.0 1.2 9.0 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family CTU2 PF10288.9 EGR32855.1 - 2.5e-10 40.6 0.4 2.5e-10 40.6 0.4 1.7 2 0 0 2 2 2 1 Cytoplasmic tRNA 2-thiolation protein 2 ATP_bind_3 PF01171.20 EGR32855.1 - 0.012 15.4 0.0 0.19 11.5 0.0 2.3 2 0 0 2 2 2 0 PP-loop family SR1P PF13790.6 EGR32855.1 - 0.075 13.1 0.4 1.8 8.7 0.1 3.1 3 0 0 3 3 3 0 SR1 protein DUF3926 PF13080.6 EGR32856.1 - 0.0052 16.7 0.2 0.011 15.6 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3926) COX17 PF05051.13 EGR32856.1 - 0.034 14.5 0.8 0.095 13.1 0.5 2.0 1 1 1 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) CS PF04969.16 EGR32857.1 - 6.7e-14 52.7 1.2 1.8e-13 51.3 0.4 2.1 2 0 0 2 2 2 1 CS domain Nudc_N PF14050.6 EGR32857.1 - 4.7e-12 45.7 0.1 1.1e-11 44.6 0.1 1.6 1 0 0 1 1 1 1 N-terminal conserved domain of Nudc. NARP1 PF12569.8 EGR32857.1 - 0.91 8.3 19.0 1.7 7.5 19.0 1.5 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ndc1_Nup PF09531.10 EGR32857.1 - 1.6 7.4 10.5 2.3 6.8 10.5 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.22 EGR32857.1 - 5.4 6.1 6.8 7.7 5.6 6.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.7 EGR32857.1 - 5.5 5.0 15.8 0.098 10.8 9.2 1.4 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein DUF4887 PF16228.5 EGR32857.1 - 7.4 6.7 47.5 0.86 9.8 41.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4887) Beach PF02138.18 EGR32858.1 - 1.8e-103 345.7 4.8 1.8e-103 345.7 4.8 1.7 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 EGR32858.1 - 1.6e-23 82.7 1.0 1.6e-23 82.7 1.0 2.1 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.32 EGR32858.1 - 0.0018 19.1 0.0 0.023 15.6 0.0 2.7 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR32858.1 - 0.14 12.5 0.3 2.4 8.5 0.0 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain UCH_N PF16674.5 EGR32858.1 - 4.1 7.4 10.5 0.11 12.4 2.2 2.6 3 0 0 3 3 3 0 N-terminal of ubiquitin carboxyl-terminal hydrolase 37 Pkinase PF00069.25 EGR32861.1 - 4.8e-25 88.4 0.1 5.4e-25 88.3 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32861.1 - 1.7e-12 47.2 0.0 1.8e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGR32862.1 - 3.1e-62 210.3 0.1 7.3e-62 209.1 0.1 1.7 1 0 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 EGR32862.1 - 3.5e-40 136.0 0.2 7e-17 61.3 0.0 3.4 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 EGR32862.1 - 9.5e-27 93.9 0.0 1.9e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR32862.1 - 2e-05 24.1 0.0 5e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR32862.1 - 0.00012 21.1 0.1 0.00042 19.2 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase HEAT_2 PF13646.6 EGR32863.1 - 0.061 13.7 0.0 0.36 11.3 0.0 2.0 1 1 0 2 2 2 0 HEAT repeats HEAT PF02985.22 EGR32863.1 - 0.1 12.9 0.0 0.66 10.4 0.0 2.3 2 1 0 2 2 2 0 HEAT repeat HSP33 PF01430.19 EGR32864.1 - 1.2e-21 77.3 0.9 3.6e-20 72.5 0.4 2.0 1 1 1 2 2 2 2 Hsp33 protein VSP PF03302.13 EGR32865.1 - 3.7 6.3 63.0 0.84 8.4 17.1 4.0 1 1 1 2 2 2 0 Giardia variant-specific surface protein LUC7 PF03194.15 EGR32866.1 - 1.4e-22 80.6 12.2 1.5e-22 80.5 10.2 1.9 1 1 1 2 2 2 1 LUC7 N_terminus DEAD PF00270.29 EGR32866.1 - 4.3e-19 69.0 0.3 8.1e-19 68.0 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR32866.1 - 1.2e-14 54.6 2.1 3.5e-14 53.1 0.4 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA PF00004.29 EGR32866.1 - 0.4 11.1 2.6 0.54 10.7 0.6 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Transformer PF06495.11 EGR32866.1 - 1.4 9.0 11.9 0.44 10.6 9.2 1.5 2 0 0 2 2 2 0 Fruit fly transformer protein A_deaminase PF00962.22 EGR32867.1 - 2.8e-26 92.6 0.1 3.4e-26 92.3 0.1 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase PrlF_antitoxin PF15937.5 EGR32868.1 - 0.0024 18.3 0.4 0.057 13.9 0.1 3.0 3 0 0 3 3 3 1 prlF antitoxin for toxin YhaV_toxin DUF5517 PF17639.2 EGR32868.1 - 2 8.8 9.6 0.22 11.8 1.8 3.0 3 1 0 3 3 3 0 Family of unknown function (DUF5517) Sec63 PF02889.16 EGR32869.1 - 1.3e-98 329.2 28.3 3.3e-54 183.8 6.6 3.8 3 1 0 3 3 3 2 Sec63 Brl domain DEAD PF00270.29 EGR32869.1 - 8.6e-49 165.7 0.2 7.4e-26 91.0 0.3 3.6 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 EGR32869.1 - 2.3e-25 89.6 0.2 1.6e-13 51.0 0.2 7.5 5 2 1 6 6 6 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGR32869.1 - 2.4e-17 63.3 0.1 3.4e-08 33.8 0.0 3.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGR32869.1 - 1e-06 29.1 3.6 0.00082 19.7 0.1 4.4 4 1 0 4 4 4 2 AAA domain T2SSE PF00437.20 EGR32869.1 - 0.00017 20.7 0.0 0.16 11.0 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein IstB_IS21 PF01695.17 EGR32869.1 - 0.049 13.4 0.1 5.2 6.8 0.0 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein VP9 PF09625.10 EGR32870.1 - 0.21 11.8 5.1 0.45 10.7 0.3 2.8 2 1 0 2 2 2 0 VP9 protein 14-3-3 PF00244.20 EGR32871.1 - 2.9e-97 324.5 6.6 3.3e-97 324.3 6.6 1.0 1 0 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 EGR32871.1 - 0.06 13.6 0.5 2.2 8.6 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat FHA PF00498.26 EGR32872.1 - 3.6e-19 68.9 1.8 4.3e-10 39.8 0.3 3.3 3 1 0 3 3 3 2 FHA domain Yop-YscD_cpl PF16697.5 EGR32872.1 - 5.1e-05 23.5 0.0 0.094 13.0 0.0 4.0 3 1 0 3 3 3 2 Inner membrane component of T3SS, cytoplasmic domain Adaptin_N PF01602.20 EGR32873.1 - 7e-80 269.1 21.4 9.1e-80 268.7 21.4 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGR32873.1 - 1.2e-06 28.7 0.1 1.2e-06 28.7 0.1 3.9 2 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGR32873.1 - 2.4e-05 24.7 0.0 2 8.9 0.0 4.3 3 1 1 4 4 4 2 HEAT repeats MMS19_N PF14500.6 EGR32873.1 - 0.00023 20.8 3.5 0.0099 15.5 0.0 3.6 3 1 0 3 3 3 1 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_EZ PF13513.6 EGR32873.1 - 0.0037 17.7 0.0 26 5.5 0.0 4.0 3 1 0 3 3 3 0 HEAT-like repeat TFCD_C PF12612.8 EGR32873.1 - 0.0098 15.7 1.2 7.9 6.3 0.1 4.1 3 1 1 4 4 4 1 Tubulin folding cofactor D C terminal Vac14_Fab1_bd PF12755.7 EGR32873.1 - 0.012 16.2 2.3 3.1 8.5 0.1 3.8 3 1 0 3 3 3 0 Vacuolar 14 Fab1-binding region RPAP3_C PF13877.6 EGR32873.1 - 0.11 13.0 4.1 11 6.6 0.0 4.2 3 1 0 3 3 3 0 Potential Monad-binding region of RPAP3 FANCI_S2 PF14676.6 EGR32873.1 - 0.17 12.2 6.4 0.55 10.5 0.6 3.8 3 1 0 3 3 3 0 FANCI solenoid 2 ERp29 PF07749.12 EGR32873.1 - 0.99 10.3 0.0 0.99 10.3 0.0 3.8 3 1 0 3 3 3 0 Endoplasmic reticulum protein ERp29, C-terminal domain DUF5071 PF16804.5 EGR32873.1 - 1.3 9.3 7.9 2.6 8.3 0.4 4.6 3 1 2 6 6 6 0 Domain of unknown function (DUF5071) LRR_6 PF13516.6 EGR32874.1 - 2.5e-06 27.1 7.7 0.71 10.1 0.8 4.8 4 0 0 4 4 4 3 Leucine Rich repeat LRR_1 PF00560.33 EGR32874.1 - 3.9e-05 23.6 8.7 1.7 9.5 0.6 5.9 5 0 0 5 5 5 1 Leucine Rich Repeat LRR_4 PF12799.7 EGR32874.1 - 0.018 15.5 14.1 0.47 11.0 4.5 3.8 1 1 4 5 5 5 0 Leucine Rich repeats (2 copies) TUG-UBL1 PF11470.8 EGR32874.1 - 0.038 14.2 1.0 0.14 12.4 1.0 2.0 1 0 0 1 1 1 0 TUG ubiquitin-like domain LRR_8 PF13855.6 EGR32874.1 - 3.3 7.5 13.5 2.2 8.1 0.5 3.7 2 2 1 3 3 3 0 Leucine rich repeat Kinesin PF00225.23 EGR32875.1 - 9.8e-76 254.8 2.6 9.8e-76 254.8 2.6 2.3 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGR32875.1 - 0.00024 21.0 0.2 0.00024 21.0 0.2 3.8 3 2 0 3 3 3 1 Microtubule binding KASH_CCD PF14662.6 EGR32875.1 - 0.017 15.0 1.3 0.017 15.0 1.3 2.6 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH LysM PF01476.20 EGR32875.1 - 1 9.5 7.5 1.8 8.7 0.1 2.9 3 0 0 3 3 3 0 LysM domain QIL1 PF15884.5 EGR32875.1 - 2.6 8.7 5.1 10 6.8 0.1 3.9 4 1 0 4 4 4 0 MICOS complex subunit MIC13, QIL1 Pkinase PF00069.25 EGR32878.1 - 5.4e-62 209.5 4.5 2.5e-38 132.0 0.6 3.3 2 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32878.1 - 4.9e-25 88.3 9.7 7.7e-20 71.3 0.4 3.1 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 EGR32878.1 - 0.00037 19.9 0.1 0.00037 19.9 0.1 3.4 4 0 0 4 4 4 1 Kinase-like FTA2 PF13095.6 EGR32878.1 - 0.022 14.4 9.1 0.5 10.0 0.1 3.7 3 1 1 4 4 4 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGR32878.1 - 0.025 13.9 0.1 0.052 12.9 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2961 PF11175.8 EGR32878.1 - 0.039 13.6 1.1 1.3 8.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2961) Fungal_trans_2 PF11951.8 EGR32878.1 - 0.041 12.7 0.8 0.073 11.9 0.8 1.3 1 0 0 1 1 1 0 Fungal specific transcription factor domain APH PF01636.23 EGR32878.1 - 0.063 13.2 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SpoOE-like PF09388.10 EGR32878.1 - 0.17 11.8 7.3 7.6 6.5 0.0 4.2 3 1 0 3 3 3 0 Spo0E like sporulation regulatory protein Atg14 PF10186.9 EGR32878.1 - 0.21 10.6 12.9 0.63 9.1 5.0 2.4 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Exonuc_VII_L PF02601.15 EGR32878.1 - 1 8.9 9.6 0.44 10.1 4.7 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit DUF16 PF01519.16 EGR32878.1 - 1.8 9.1 20.1 0.073 13.6 5.4 3.3 3 0 0 3 3 3 0 Protein of unknown function DUF16 Fibin PF15819.5 EGR32878.1 - 2.5 7.8 8.2 0.92 9.2 2.0 2.3 2 0 0 2 2 2 0 Fin bud initiation factor homologue DUF1428 PF07237.11 EGR32879.1 - 0.035 14.4 0.6 0.11 12.8 0.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1428) GSH_synth_ATP PF03917.17 EGR32884.1 - 1.6e-75 254.2 5.9 1.8e-75 254.0 5.9 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EGR32884.1 - 6.5e-31 106.8 0.4 2.4e-30 105.0 0.4 2.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase DUF4130 PF13566.6 EGR32884.1 - 0.051 13.6 0.7 0.19 11.8 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4130 IFT81_CH PF18383.1 EGR32885.1 - 6.4e-35 120.1 1.4 6.4e-35 120.1 1.4 2.8 3 1 0 3 3 3 1 Intraflagellar transport 81 calponin homology domain Rad10 PF03834.14 EGR32885.1 - 0.045 13.8 0.5 0.045 13.8 0.5 2.9 3 0 0 3 3 3 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) GM_CSF PF01109.17 EGR32885.1 - 5.9 7.1 7.9 6.4 7.0 0.0 3.4 3 0 0 3 3 3 0 Granulocyte-macrophage colony-stimulating factor DnaJ_C PF01556.18 EGR32886.1 - 2e-30 105.8 1.5 2.8e-30 105.4 1.5 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EGR32886.1 - 4.4e-14 52.6 19.5 8.5e-14 51.7 19.5 1.5 1 0 0 1 1 1 1 DnaJ central domain Tfb5 PF06331.12 EGR32886.1 - 0.043 13.8 0.1 0.084 12.9 0.1 1.4 1 0 0 1 1 1 0 Transcription factor TFIIH complex subunit Tfb5 Anti-TRAP PF15777.5 EGR32886.1 - 0.061 13.3 8.8 0.55 10.2 1.0 2.4 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein TackOD1 PF18551.1 EGR32886.1 - 0.74 9.4 8.5 5.1 6.7 0.5 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 HypA PF01155.19 EGR32886.1 - 1.4 8.9 11.7 3.1 7.9 3.2 2.3 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA GIDA PF01134.22 EGR32887.1 - 1e-146 489.0 0.3 1.5e-146 488.5 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EGR32887.1 - 4.1e-61 206.8 0.9 7.1e-61 206.1 0.9 1.4 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 EGR32887.1 - 1.1e-07 31.4 0.2 2.1e-07 30.5 0.2 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGR32887.1 - 3.2e-07 30.0 0.0 5.8e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGR32887.1 - 4.1e-07 29.0 1.0 0.017 13.8 0.2 3.3 3 0 0 3 3 3 3 HI0933-like protein FAD_binding_2 PF00890.24 EGR32887.1 - 5.1e-06 25.8 0.3 5.9e-05 22.3 0.6 2.1 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EGR32887.1 - 1.2e-05 24.7 0.0 0.036 13.3 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGR32887.1 - 0.00024 20.4 0.0 0.0081 15.5 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 EGR32887.1 - 0.0024 18.4 0.1 0.0061 17.1 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGR32887.1 - 0.0025 16.9 0.3 0.017 14.2 0.3 2.0 1 1 0 1 1 1 1 Lycopene cyclase protein NAD_binding_8 PF13450.6 EGR32887.1 - 0.064 13.5 0.5 0.18 12.1 0.3 1.9 2 0 0 2 2 1 0 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGR32887.1 - 0.069 12.4 0.5 0.54 9.4 0.5 2.1 1 1 0 1 1 1 0 Thi4 family DAO PF01266.24 EGR32887.1 - 0.094 12.3 0.0 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGR32887.1 - 0.16 11.2 0.1 0.24 10.6 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain DJ-1_PfpI PF01965.24 EGR32887.1 - 0.2 11.5 0.0 0.41 10.4 0.0 1.5 1 0 0 1 1 1 0 DJ-1/PfpI family Pkinase PF00069.25 EGR32888.1 - 1.2e-41 142.9 0.9 2e-41 142.1 0.9 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32888.1 - 2.4e-20 72.9 0.0 3.1e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR32888.1 - 0.0091 14.8 0.1 0.012 14.4 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR32888.1 - 0.094 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EGR32889.1 - 3.7e-67 226.5 1.0 5.1e-67 226.0 1.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32889.1 - 2.7e-40 138.3 0.1 3.9e-40 137.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR32889.1 - 1.2e-05 24.8 0.0 3.3e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR32889.1 - 0.021 13.6 0.0 0.049 12.4 0.0 1.5 1 0 0 1 1 1 0 Fungal protein kinase Gln-synt_C PF00120.24 EGR32890.1 - 3.5e-18 65.7 0.0 6.4e-15 55.0 0.0 2.1 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 EGR32890.1 - 9.6e-07 28.5 0.0 1.9e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain RIIa PF02197.17 EGR32891.1 - 1.1e-10 41.0 0.1 2e-10 40.1 0.1 1.4 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit IQ PF00612.27 EGR32891.1 - 0.031 14.0 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif UPF0242 PF06785.11 EGR32891.1 - 2.3 8.3 17.2 3.1 7.8 17.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus LMBR1 PF04791.16 EGR32891.1 - 6.3 5.6 7.7 6.9 5.5 7.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein CDC50 PF03381.15 EGR32892.1 - 1.2e-52 179.2 17.2 1.2e-52 179.2 17.2 1.6 2 0 0 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family PHD PF00628.29 EGR32896.1 - 2.3e-07 30.6 15.6 5.5e-07 29.4 9.8 2.7 2 0 0 2 2 2 1 PHD-finger C1_1 PF00130.22 EGR32896.1 - 0.003 17.4 10.0 0.003 17.4 10.0 3.2 2 1 1 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_4 PF16866.5 EGR32896.1 - 1.2 9.3 16.6 2.6 8.2 9.2 2.7 1 1 2 3 3 3 0 PHD-finger C1_2 PF03107.16 EGR32896.1 - 1.7 9.1 24.4 0.16 12.3 7.8 3.5 2 1 1 3 3 3 0 C1 domain zf-C3HC4_3 PF13920.6 EGR32896.1 - 4.8 7.1 15.1 0.31 10.9 1.8 3.3 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) SNARE PF05739.19 EGR32897.1 - 3.5e-10 39.7 0.3 7.9e-10 38.6 0.3 1.6 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EGR32897.1 - 5.3e-09 36.0 9.1 5.3e-09 36.0 9.1 1.9 2 0 0 2 2 2 1 Syntaxin DUF2951 PF11166.8 EGR32897.1 - 0.00017 21.7 1.0 0.00017 21.7 1.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2951) TMCO5 PF14992.6 EGR32897.1 - 0.011 15.4 13.5 0.017 14.7 13.5 1.4 1 1 0 1 1 1 0 TMCO5 family DUF1154 PF06631.11 EGR32897.1 - 0.011 15.8 2.6 0.027 14.5 2.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1154) DUF5402 PF17393.2 EGR32897.1 - 0.043 13.8 0.1 0.078 12.9 0.1 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5402) MCPsignal PF00015.21 EGR32897.1 - 0.064 13.1 1.9 0.11 12.3 0.3 1.9 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain OHCU_decarbox PF09349.10 EGR32897.1 - 0.16 12.4 2.8 0.23 11.9 2.8 1.3 1 1 0 1 1 1 0 OHCU decarboxylase DUF4917 PF16263.5 EGR32897.1 - 0.25 10.6 4.6 2.3 7.5 0.7 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4917) DUF1910 PF08928.10 EGR32897.1 - 0.27 11.2 9.1 0.05 13.6 4.8 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1910) Sec20 PF03908.13 EGR32897.1 - 0.29 11.1 7.1 1.7 8.6 1.5 2.9 1 1 1 3 3 3 0 Sec20 CC2-LZ PF16516.5 EGR32897.1 - 0.29 11.5 13.5 0.46 10.9 1.5 3.1 1 1 3 4 4 4 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF745 PF05335.13 EGR32897.1 - 2.5 7.8 11.3 0.46 10.2 3.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF745) V-SNARE PF05008.15 EGR32897.1 - 5.4 7.5 12.5 5.5 7.4 5.0 2.2 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus PCRF PF03462.18 EGR32897.1 - 5.4 6.8 9.5 0.76 9.6 3.0 2.0 1 1 1 2 2 2 0 PCRF domain ASH PF15780.5 EGR32898.1 - 2.2e-06 27.8 0.1 5.1e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin TMEM131_like PF12371.8 EGR32898.1 - 0.001 19.3 0.1 0.0044 17.2 0.1 1.9 2 0 0 2 2 2 1 Transmembrane protein 131-like PPP5 PF08321.12 EGR32899.1 - 0.044 14.1 0.9 0.14 12.5 0.5 2.1 2 0 0 2 2 2 0 PPP5 TPR repeat region Peptidase_M8 PF01457.16 EGR32901.1 - 8.3e-47 160.1 0.7 6e-42 144.0 0.0 2.0 1 1 1 2 2 2 2 Leishmanolysin Peptidase_M8 PF01457.16 EGR32902.1 - 4.1e-15 55.5 0.1 4.5e-15 55.3 0.1 1.0 1 0 0 1 1 1 1 Leishmanolysin PSCyt2 PF07583.11 EGR32902.1 - 0.047 13.6 0.0 0.052 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) Pkinase PF00069.25 EGR32907.1 - 7.6e-61 205.8 2.6 9.1e-61 205.5 2.6 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32907.1 - 2.1e-37 128.8 0.3 2.8e-37 128.4 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR32907.1 - 0.0011 18.4 0.9 0.0033 16.8 0.1 2.1 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR32907.1 - 0.021 13.6 0.1 0.033 12.9 0.1 1.4 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 EGR32907.1 - 0.046 13.6 0.0 0.087 12.7 0.0 1.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family ABC2_membrane PF01061.24 EGR32908.1 - 5.1e-42 143.7 15.5 7.8e-42 143.1 15.5 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGR32908.1 - 1.7e-26 93.4 0.9 3.6e-25 89.1 0.1 2.4 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 EGR32908.1 - 4.8e-06 25.9 18.1 8.9e-06 25.0 18.1 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EGR32908.1 - 2.1e-05 24.5 0.1 6.2e-05 23.0 0.1 1.8 1 0 0 1 1 1 1 RsgA GTPase AAA_18 PF13238.6 EGR32908.1 - 0.00049 20.6 0.2 0.0037 17.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain ABC2_membrane_2 PF12679.7 EGR32908.1 - 0.00052 19.4 3.8 0.0022 17.4 3.8 2.0 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGR32908.1 - 0.00095 19.1 3.2 0.044 13.6 0.5 2.8 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGR32908.1 - 0.0014 18.3 0.1 0.0032 17.2 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_24 PF13479.6 EGR32908.1 - 0.0015 18.3 0.9 0.04 13.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EGR32908.1 - 0.0025 18.2 0.0 0.005 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 EGR32908.1 - 0.0026 18.1 0.0 0.0067 16.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_23 PF13476.6 EGR32908.1 - 0.0033 18.0 0.7 0.0033 18.0 0.7 3.2 2 1 1 3 3 3 1 AAA domain AAA_22 PF13401.6 EGR32908.1 - 0.0072 16.6 0.0 0.022 15.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EGR32908.1 - 0.023 14.1 0.5 0.49 9.8 0.5 2.4 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain NTPase_1 PF03266.15 EGR32908.1 - 0.024 14.5 0.2 0.12 12.3 0.0 2.1 2 0 0 2 2 2 0 NTPase T2SSE PF00437.20 EGR32908.1 - 0.033 13.2 0.0 0.062 12.4 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein dNK PF01712.19 EGR32908.1 - 0.036 13.9 0.0 0.08 12.8 0.0 1.6 1 0 0 1 1 1 0 Deoxynucleoside kinase Rad17 PF03215.15 EGR32908.1 - 0.083 12.8 0.1 0.083 12.8 0.1 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 EGR32908.1 - 0.24 11.6 0.1 0.41 10.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 EGR32908.1 - 0.26 11.3 2.9 0.86 9.6 0.1 2.6 3 0 0 3 3 3 0 Helicase HerA, central domain Ammonium_transp PF00909.21 EGR32909.1 - 3.3e-39 134.7 15.2 2.3e-20 72.7 10.8 2.1 2 0 0 2 2 2 2 Ammonium Transporter Family DUF389 PF04087.14 EGR32909.1 - 1.5 8.9 9.5 2.1 8.4 0.5 4.2 2 2 3 5 5 5 0 Domain of unknown function (DUF389) PNTB PF02233.16 EGR32910.1 - 8.8e-07 28.2 4.7 3.8e-06 26.1 1.7 2.0 1 1 1 2 2 2 2 NAD(P) transhydrogenase beta subunit Phage_holin_2_4 PF16082.5 EGR32910.1 - 0.066 13.0 0.5 0.1 12.3 0.5 1.3 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like ExoD PF06055.12 EGR32910.1 - 0.29 10.5 1.7 0.36 10.2 1.7 1.1 1 0 0 1 1 1 0 Exopolysaccharide synthesis, ExoD PNTB_4TM PF12769.7 EGR32911.1 - 2.8e-15 56.6 5.9 5.1e-15 55.7 4.1 1.9 2 0 0 2 2 2 1 4TM region of pyridine nucleotide transhydrogenase, mitoch DUF2207 PF09972.9 EGR32911.1 - 0.00092 18.1 0.9 0.0013 17.6 0.9 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4962 PF16332.5 EGR32911.1 - 0.15 10.5 0.1 0.2 10.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) Bac_export_2 PF01312.19 EGR32911.1 - 0.16 11.2 1.8 0.21 10.8 1.8 1.1 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Shisa PF13908.6 EGR32911.1 - 3.8 7.7 5.8 20 5.4 5.8 2.0 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Pkinase PF00069.25 EGR32912.1 - 9.2e-41 139.9 0.0 1.3e-40 139.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32912.1 - 2.1e-26 92.8 0.0 2.9e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR32912.1 - 9.2e-06 24.7 0.0 1.6e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGR32912.1 - 0.0017 17.7 0.0 0.0037 16.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGR32912.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family WD40 PF00400.32 EGR32913.1 - 2e-10 41.1 9.4 0.0018 19.0 0.2 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR32913.1 - 0.0074 16.6 0.1 6.8 7.1 0.0 3.9 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_M16_C PF05193.21 EGR32914.1 - 8.1e-13 48.8 0.7 4e-11 43.3 0.0 2.7 3 0 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGR32914.1 - 1.1e-08 35.1 1.1 1.7e-08 34.6 0.2 1.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Rsm22 PF09243.10 EGR32914.1 - 0.25 10.6 0.4 0.38 10.0 0.4 1.2 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 GTP_EFTU PF00009.27 EGR32916.1 - 2e-36 125.4 0.0 6.9e-36 123.6 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EGR32916.1 - 9.2e-20 70.7 0.2 6.6e-19 68.0 0.1 2.6 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D4 PF14578.6 EGR32916.1 - 8.2e-11 41.7 0.6 2.9e-10 39.9 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.25 EGR32916.1 - 6.3e-10 39.3 14.4 1.7e-07 31.5 0.0 4.1 5 1 0 5 5 5 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGR32916.1 - 3.5e-08 33.5 0.0 3.5e-08 33.5 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGR32916.1 - 1.5e-05 25.0 6.0 0.013 15.5 0.4 3.3 2 1 1 3 3 3 2 RsgA GTPase Roc PF08477.13 EGR32916.1 - 0.00094 19.4 0.0 0.0047 17.1 0.0 2.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 EGR32916.1 - 0.014 15.6 1.0 0.052 13.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGR32916.1 - 0.15 11.8 0.0 0.41 10.4 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNA_pol_Rpb4 PF03874.16 EGR32917.1 - 0.015 15.6 4.3 0.022 15.1 4.3 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb4 TPR_12 PF13424.6 EGR32918.1 - 0.38 11.1 8.5 3 8.2 4.4 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGR32918.1 - 0.86 10.2 0.0 0.86 10.2 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat MAD PF05557.13 EGR32919.1 - 0.043 12.2 35.5 0.05 12.0 35.5 1.0 1 0 0 1 1 1 0 Mitotic checkpoint protein TPR_MLP1_2 PF07926.12 EGR32919.1 - 1.1 9.3 36.7 0.25 11.4 16.8 3.1 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein LMBR1 PF04791.16 EGR32919.1 - 2.3 7.0 20.3 3.3 6.5 20.3 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF3450 PF11932.8 EGR32919.1 - 5.1 6.3 30.1 0.11 11.8 7.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Sugar_tr PF00083.24 EGR32920.1 - 5.8e-50 170.5 25.5 7.7e-50 170.1 25.5 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGR32920.1 - 1.9e-18 66.6 4.5 1.9e-18 66.6 4.5 2.6 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EGR32920.1 - 0.00047 18.7 2.3 0.00047 18.7 2.3 2.1 2 0 0 2 2 2 1 Transmembrane secretion effector DUF1774 PF08611.10 EGR32920.1 - 0.0059 16.9 1.8 0.0059 16.9 1.8 3.0 3 1 0 3 3 3 1 Fungal protein of unknown function (DUF1774) CBM_20 PF00686.19 EGR32921.1 - 2.1e-18 66.0 0.1 2.4e-18 65.8 0.1 1.0 1 0 0 1 1 1 1 Starch binding domain CDC50 PF03381.15 EGR32922.1 - 8.2e-57 192.8 13.3 8.2e-57 192.8 13.3 2.1 1 1 1 2 2 2 2 LEM3 (ligand-effect modulator 3) family / CDC50 family DUF3899 PF13038.6 EGR32922.1 - 0.00067 20.1 3.5 1.4 9.5 0.0 3.6 2 1 1 3 3 3 2 Domain of unknown function (DUF3899) GP41 PF00517.17 EGR32924.1 - 1.2 9.0 19.3 2.4 8.0 19.3 1.6 1 1 0 1 1 1 0 Retroviral envelope protein Dus PF01207.17 EGR32925.1 - 1.7e-57 194.9 0.0 1.9e-57 194.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) XPC-binding PF09280.11 EGR32925.1 - 0.05 13.3 1.2 10 5.9 0.0 3.5 4 0 0 4 4 4 0 XPC-binding domain His_biosynth PF00977.21 EGR32925.1 - 0.15 11.5 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein DSPc PF00782.20 EGR32926.1 - 1.3e-18 67.1 4.7 1.3e-18 67.1 4.7 2.7 2 1 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Sigma54_activ_2 PF14532.6 EGR32926.1 - 0.045 13.9 1.6 1.2 9.3 0.9 2.8 1 1 0 1 1 1 0 Sigma-54 interaction domain Urm1 PF09138.11 EGR32926.1 - 0.46 10.9 9.1 1.5 9.2 1.5 3.9 2 2 1 3 3 3 0 Urm1 (Ubiquitin related modifier) NADH5_C PF06455.11 EGR32926.1 - 0.48 10.0 3.8 0.94 9.0 3.8 1.5 1 0 0 1 1 1 0 NADH dehydrogenase subunit 5 C-terminus LRR_4 PF12799.7 EGR32927.1 - 0.013 15.9 2.6 0.013 15.9 2.6 4.0 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) Peptidase_M15_2 PF05951.13 EGR32927.1 - 0.021 14.5 0.5 0.075 12.7 0.5 2.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF882) LRR_6 PF13516.6 EGR32927.1 - 0.092 12.8 7.7 12 6.2 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeat RP-C_C PF11800.8 EGR32927.1 - 1.6 8.8 4.4 0.7 9.9 2.0 1.6 2 0 0 2 2 2 0 Replication protein C C-terminal region RRM_1 PF00076.22 EGR32928.1 - 2.1e-20 72.3 0.3 3.4e-20 71.6 0.3 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGR32928.1 - 0.00015 21.4 0.1 0.0002 20.9 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGR32928.1 - 0.00082 19.4 0.0 0.0074 16.4 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif zf-CCHC_4 PF14392.6 EGR32928.1 - 0.13 12.0 1.3 0.33 10.7 1.3 1.7 1 0 0 1 1 1 0 Zinc knuckle DEAD PF00270.29 EGR32929.1 - 1.9e-50 171.1 4.5 3.9e-49 166.8 0.0 3.1 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR32929.1 - 1.6e-25 89.6 0.2 1.6e-25 89.6 0.2 4.9 3 2 2 5 5 5 1 Helicase conserved C-terminal domain Ion_trans_2 PF07885.16 EGR32930.1 - 1.2e-13 50.8 0.4 2.5e-13 49.8 0.4 1.5 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 EGR32930.1 - 1.5e-07 31.4 0.0 2.6e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 EGR32930.1 - 1.8e-07 30.6 1.1 3.5e-07 29.7 1.1 1.4 1 0 0 1 1 1 1 Ion transport protein zf-CCHC PF00098.23 EGR32930.1 - 0.0035 17.3 0.2 0.0061 16.6 0.2 1.3 1 0 0 1 1 1 1 Zinc knuckle Glycophorin_A PF01102.18 EGR32932.1 - 0.0097 16.1 1.5 0.053 13.8 1.5 2.3 1 0 0 1 1 1 1 Glycophorin A GlnE PF03710.15 EGR32932.1 - 7.1 6.0 7.8 0.5 9.7 2.0 1.8 1 1 1 2 2 2 0 Glutamate-ammonia ligase adenylyltransferase zf-C2HC_2 PF13913.6 EGR32934.1 - 8.1e-22 76.6 26.3 1.8e-11 43.6 0.5 4.2 4 0 0 4 4 4 3 zinc-finger of a C2HC-type DUF2318 PF10080.9 EGR32934.1 - 0.00031 20.8 13.1 0.0014 18.7 0.2 4.2 3 1 1 4 4 4 2 Predicted membrane protein (DUF2318) zf-C2H2_4 PF13894.6 EGR32934.1 - 0.037 14.9 17.0 2.1 9.4 0.7 4.5 4 0 0 4 4 4 0 C2H2-type zinc finger zf-C2H2_11 PF16622.5 EGR32934.1 - 0.13 12.0 2.6 0.72 9.7 0.1 2.7 2 0 0 2 2 2 0 zinc-finger C2H2-type LAP1C PF05609.12 EGR32934.1 - 0.32 10.0 14.8 0.45 9.6 14.8 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) zf_UBZ PF18439.1 EGR32934.1 - 0.48 10.1 15.3 0.96 9.1 0.0 4.0 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-C2H2 PF00096.26 EGR32934.1 - 0.5 10.9 11.7 13 6.5 0.1 4.3 4 0 0 4 4 4 0 Zinc finger, C2H2 type DUF2256 PF10013.9 EGR32934.1 - 0.96 9.6 5.2 35 4.6 0.1 3.9 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2256) zf-H2C2_2 PF13465.6 EGR32934.1 - 6.2 7.4 6.9 32 5.2 0.0 3.9 4 0 0 4 4 4 0 Zinc-finger double domain Aminotran_3 PF00202.21 EGR32936.1 - 2.5e-80 270.1 0.0 3.1e-80 269.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III HP1451_C PF18472.1 EGR32936.1 - 0.036 14.0 0.5 2.3 8.2 0.0 2.6 2 0 0 2 2 2 0 HP1451 C-terminal domain CHAT PF12770.7 EGR32937.1 - 1.7e-06 27.7 0.0 2.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 CHAT domain AAA_16 PF13191.6 EGR32937.1 - 1.7e-06 28.5 0.0 3.5e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain ATPase_2 PF01637.18 EGR32937.1 - 0.00029 20.8 0.8 0.0016 18.4 0.0 2.2 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea NB-ARC PF00931.22 EGR32937.1 - 0.033 13.4 0.0 0.072 12.3 0.0 1.6 1 0 0 1 1 1 0 NB-ARC domain PhoH PF02562.16 EGR32937.1 - 0.04 13.4 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Proteasome PF00227.26 EGR32938.1 - 1.6e-41 141.9 0.0 1.9e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGR32938.1 - 5e-09 35.7 1.7 5e-09 35.7 0.1 1.9 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Acyl-CoA_dh_M PF02770.19 EGR32939.1 - 6.5e-14 51.9 0.0 1.5e-13 50.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.19 EGR32939.1 - 2.4e-11 43.5 0.0 4e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_1 PF00441.24 EGR32939.1 - 0.00021 21.5 0.0 0.00058 20.1 0.0 1.8 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Adaptin_N PF01602.20 EGR32940.1 - 8.5e-80 268.8 16.9 8.7e-57 192.9 6.4 2.2 1 1 1 2 2 2 2 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EGR32940.1 - 1.5e-16 60.6 6.2 1.5e-16 60.6 6.2 2.5 2 0 0 2 2 2 1 Adaptin C-terminal domain Cnd1 PF12717.7 EGR32940.1 - 2.7e-06 27.5 18.0 2.1e-05 24.6 3.2 3.4 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 BDV_P24 PF06595.11 EGR32940.1 - 0.06 13.2 0.3 0.19 11.6 0.0 1.9 2 0 0 2 2 2 0 Borna disease virus P24 protein DUF4476 PF14771.6 EGR32940.1 - 2.5 8.4 8.1 0.5 10.7 1.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4476) SRP68 PF16969.5 EGR32941.1 - 1.3e-76 258.8 15.7 1.6e-76 258.5 15.7 1.1 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 Suv3_N PF18114.1 EGR32941.1 - 0.11 12.7 4.0 0.076 13.1 0.7 2.4 2 0 0 2 2 2 0 Suv3 helical N-terminal domain DUF2018 PF09442.10 EGR32942.1 - 5.7 8.0 10.1 0.21 12.6 0.7 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF2018) PEX11 PF05648.14 EGR32944.1 - 5.2e-46 156.9 2.9 5.8e-46 156.7 2.9 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) HIGH_NTase1 PF05636.11 EGR32944.1 - 0.04 13.1 0.7 0.066 12.4 0.7 1.3 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase Lipase_GDSL PF00657.22 EGR32944.1 - 0.16 11.9 0.6 0.59 10.1 0.5 1.8 2 0 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase RTP1_C1 PF10363.9 EGR32944.1 - 0.17 12.0 1.7 0.15 12.2 0.4 1.6 2 0 0 2 2 2 0 Required for nuclear transport of RNA pol II C-terminus 1 Na_Ca_ex PF01699.24 EGR32945.1 - 4e-30 104.8 34.1 2.4e-17 63.3 4.3 3.2 2 1 1 3 3 3 2 Sodium/calcium exchanger protein DUF5310 PF17237.2 EGR32945.1 - 0.041 13.7 2.5 0.19 11.6 2.5 2.3 1 0 0 1 1 1 0 Family of unknown function (DUF5310) Pkinase PF00069.25 EGR32946.1 - 8.4e-41 140.1 0.1 8.4e-41 140.1 0.1 2.6 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32946.1 - 4.1e-21 75.4 0.0 8.6e-21 74.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR32946.1 - 8.7e-07 28.5 3.5 1.3e-06 28.0 0.0 2.5 2 1 0 2 2 2 1 Kinase-like Peptidase_C31 PF05410.13 EGR32946.1 - 0.037 14.1 0.0 0.066 13.3 0.0 1.3 1 0 0 1 1 1 0 Porcine arterivirus-type cysteine proteinase alpha APH PF01636.23 EGR32946.1 - 0.064 13.2 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family SMC_N PF02463.19 EGR32947.1 - 4.7e-23 81.8 0.0 5.7e-23 81.5 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGR32947.1 - 1.6e-11 45.1 0.5 2e-11 44.8 0.5 1.2 1 0 0 1 1 1 1 AAA domain AAA_15 PF13175.6 EGR32947.1 - 1.9e-10 41.0 0.7 2e-10 40.9 0.7 1.1 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGR32947.1 - 1.3e-07 31.3 0.0 3e-07 30.1 0.0 1.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EGR32947.1 - 5.9e-07 29.6 0.1 7.6e-07 29.2 0.1 1.3 1 1 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system DUF2813 PF11398.8 EGR32947.1 - 0.00043 19.7 0.0 0.00057 19.2 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2813) ABC_tran PF00005.27 EGR32947.1 - 0.00046 20.7 0.1 0.00063 20.3 0.1 1.3 1 1 0 1 1 1 1 ABC transporter Rad17 PF03215.15 EGR32947.1 - 0.00075 19.5 0.0 0.00087 19.3 0.0 1.2 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_27 PF13514.6 EGR32947.1 - 0.0033 17.1 0.0 0.0049 16.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGR32947.1 - 0.11 12.5 0.0 0.46 10.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EGR32947.1 - 0.12 12.7 0.0 0.19 12.2 0.0 1.6 1 1 0 1 1 1 0 RNA helicase SMC_hinge PF06470.13 EGR32948.1 - 2.7e-09 37.4 3.4 3.2e-09 37.1 0.1 3.0 3 1 0 3 3 3 1 SMC proteins Flexible Hinge Domain Tape_meas_lam_C PF09718.10 EGR32948.1 - 0.042 14.0 1.0 0.27 11.4 0.0 2.7 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DSPc PF00782.20 EGR32949.1 - 2.3e-20 72.8 0.5 2.3e-20 72.8 0.5 3.2 2 1 3 5 5 5 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 EGR32949.1 - 0.015 15.6 0.4 0.05 13.9 0.0 2.1 2 0 0 2 2 2 0 Rit1 DUSP-like domain zf-RING_2 PF13639.6 EGR32950.1 - 8.8e-13 48.4 6.6 1.9e-12 47.3 6.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGR32950.1 - 7.8e-10 38.3 4.6 7.8e-10 38.3 4.6 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGR32950.1 - 4.9e-09 35.9 5.1 9.7e-09 34.9 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGR32950.1 - 3.1e-07 30.1 7.0 3.1e-07 30.1 7.0 2.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGR32950.1 - 1.9e-06 28.0 7.7 1.9e-06 28.0 7.7 2.1 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGR32950.1 - 2.7e-06 27.2 6.7 2.7e-06 27.2 6.7 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGR32950.1 - 6.5e-06 25.9 5.0 1.3e-05 25.0 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGR32950.1 - 9.2e-06 25.6 3.9 1.2e-05 25.3 2.2 2.2 2 1 0 2 2 1 1 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EGR32950.1 - 0.0014 18.3 5.0 0.0037 16.9 5.0 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EGR32950.1 - 0.0034 17.4 4.7 0.0092 16.0 4.7 1.8 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EGR32950.1 - 0.0044 16.8 6.1 0.012 15.4 6.0 1.9 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 SAPS PF04499.15 EGR32950.1 - 0.0078 15.0 10.5 0.0097 14.7 10.5 1.0 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Nop14 PF04147.12 EGR32950.1 - 0.01 14.1 12.8 0.01 14.1 12.8 1.0 1 0 0 1 1 1 0 Nop14-like family RINGv PF12906.7 EGR32950.1 - 0.01 15.9 7.2 0.013 15.7 5.0 2.2 2 1 0 2 2 2 0 RING-variant domain CDC45 PF02724.14 EGR32950.1 - 0.094 11.0 12.5 0.11 10.8 12.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 EGR32950.1 - 0.19 11.4 16.4 0.33 10.7 16.4 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein C1_2 PF03107.16 EGR32950.1 - 0.3 11.4 6.6 0.47 10.8 1.9 2.5 2 0 0 2 2 2 0 C1 domain SDA1 PF05285.12 EGR32950.1 - 0.55 9.6 16.3 0.65 9.4 16.3 1.1 1 0 0 1 1 1 0 SDA1 FANCL_C PF11793.8 EGR32950.1 - 0.67 10.2 11.0 0.085 13.0 5.7 2.3 2 1 0 2 2 2 0 FANCL C-terminal domain DNA_pol_phi PF04931.13 EGR32950.1 - 0.78 7.8 20.0 0.96 7.5 20.0 1.1 1 0 0 1 1 1 0 DNA polymerase phi zf-C3HC4_4 PF15227.6 EGR32950.1 - 1 9.5 8.1 12 6.2 8.0 2.5 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING PNISR PF15996.5 EGR32950.1 - 3.5 7.8 13.9 4.7 7.4 13.9 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DUF2457 PF10446.9 EGR32950.1 - 4.1 6.5 19.7 5.9 5.9 19.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) YL1 PF05764.13 EGR32950.1 - 6.5 6.8 18.9 9 6.3 18.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Aminotran_1_2 PF00155.21 EGR32952.1 - 3.9e-24 85.5 0.0 4.9e-24 85.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGR32952.1 - 0.00059 18.5 0.0 0.00084 18.0 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGR32952.1 - 0.088 11.7 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Yop-YscD_ppl PF16693.5 EGR32952.1 - 0.13 11.7 0.6 3.7 6.9 0.4 2.0 2 0 0 2 2 2 0 Inner membrane component of T3SS, periplasmic domain S1-P1_nuclease PF02265.16 EGR32954.1 - 1.4e-48 166.0 0.0 1.6e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 S1/P1 Nuclease PNP_UDP_1 PF01048.20 EGR32955.1 - 3.4e-12 46.1 0.0 3.6e-12 46.0 0.0 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily Pox_F15 PF04596.12 EGR32955.1 - 0.02 14.7 0.7 0.023 14.4 0.7 1.2 1 0 0 1 1 1 0 Poxvirus protein F15 HEAT_2 PF13646.6 EGR32956.1 - 3e-13 50.0 0.0 0.00046 20.5 0.0 3.0 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.22 EGR32956.1 - 4.6e-05 23.3 0.0 1.4 9.4 0.0 4.1 4 0 0 4 4 4 2 HEAT repeat HEAT_PBS PF03130.16 EGR32956.1 - 0.0027 18.2 0.0 20 6.2 0.0 4.6 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat HEAT_EZ PF13513.6 EGR32956.1 - 0.0027 18.2 0.0 7.4 7.2 0.0 3.5 3 0 0 3 3 3 2 HEAT-like repeat DUF818 PF05677.12 EGR32957.1 - 2.1e-09 36.8 0.1 2.7e-09 36.5 0.1 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Hydrolase_4 PF12146.8 EGR32957.1 - 0.00012 21.4 0.0 0.00014 21.2 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR32957.1 - 0.00021 21.0 0.0 0.00023 20.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EGR32957.1 - 0.018 14.6 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF1897 PF09005.10 EGR32957.1 - 0.077 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1897) BAAT_C PF08840.11 EGR32957.1 - 0.096 12.6 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Pyridoxal_deC PF00282.19 EGR32958.1 - 4.4e-11 42.1 0.0 1.2e-10 40.7 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGR32958.1 - 0.00024 20.2 0.0 0.00051 19.1 0.0 1.5 1 0 0 1 1 1 1 Aminotransferase class-V Hexapep PF00132.24 EGR32959.1 - 1.6e-10 40.3 18.6 3e-06 26.7 5.0 3.5 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGR32959.1 - 0.00062 19.5 4.6 0.0014 18.3 2.8 2.2 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EGR32959.1 - 0.00083 18.4 0.0 0.00094 18.2 0.0 1.1 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 EGR32959.1 - 0.044 11.9 0.9 0.053 11.7 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) DOR PF14839.6 EGR32961.1 - 4.8 7.1 7.3 6 6.7 7.3 1.2 1 0 0 1 1 1 0 DOR family Proteasome PF00227.26 EGR32962.1 - 1.3e-33 116.1 0.1 1.2e-31 109.6 0.1 2.0 1 1 0 1 1 1 1 Proteasome subunit Dicty_CAD PF05720.12 EGR32963.1 - 9.5e-13 48.0 10.5 1.9 8.5 0.1 6.5 6 0 0 6 6 6 6 Cell-cell adhesion domain MVL PF12151.8 EGR32963.1 - 0.035 14.0 14.0 1e+02 2.9 0.1 6.8 6 0 0 6 6 6 0 Mannan-binding protein TPR_1 PF00515.28 EGR32964.1 - 2.7e-53 175.7 57.4 2.8e-08 33.3 1.3 10.1 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 EGR32964.1 - 1.4e-49 162.3 37.7 1.8e-08 33.9 1.3 10.0 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 EGR32964.1 - 2.2e-33 111.7 40.9 7.1e-07 29.0 1.1 9.9 10 0 0 10 10 10 8 Tetratricopeptide repeat TPR_11 PF13414.6 EGR32964.1 - 2.5e-30 103.9 47.9 3.8e-07 29.7 2.0 9.8 2 1 8 10 10 10 8 TPR repeat TPR_17 PF13431.6 EGR32964.1 - 1.3e-27 94.2 40.6 3.6e-05 23.9 2.0 9.4 10 0 0 10 10 9 7 Tetratricopeptide repeat TPR_12 PF13424.6 EGR32964.1 - 1.6e-26 92.4 24.1 7e-08 32.7 1.3 7.5 2 2 4 7 7 7 5 Tetratricopeptide repeat TPR_6 PF13174.6 EGR32964.1 - 9.6e-26 88.7 18.9 0.00016 22.1 0.3 9.1 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_19 PF14559.6 EGR32964.1 - 9.7e-25 86.9 21.4 1.2e-07 32.2 1.3 6.8 2 2 6 8 8 8 7 Tetratricopeptide repeat TPR_16 PF13432.6 EGR32964.1 - 4.6e-21 75.2 0.0 0.00011 22.7 0.0 5.2 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGR32964.1 - 7.6e-19 66.8 0.0 0.036 14.9 0.0 7.5 2 2 6 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 EGR32964.1 - 4.6e-18 63.8 21.8 0.0013 18.6 0.1 8.9 7 2 2 9 9 9 6 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR32964.1 - 2.8e-16 59.5 31.7 0.00026 21.2 0.3 5.0 2 1 4 6 6 6 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGR32964.1 - 2.5e-11 43.6 0.0 0.0085 16.2 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_20 PF14561.6 EGR32964.1 - 3.3e-11 43.4 4.0 0.079 13.3 0.0 5.4 2 1 4 6 6 6 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGR32964.1 - 1.9e-10 40.3 17.0 0.0092 15.8 0.3 8.2 9 0 0 9 9 9 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGR32964.1 - 5.2e-10 39.2 28.0 0.00062 19.8 0.5 7.6 5 3 3 8 8 8 3 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 EGR32964.1 - 9.2e-08 31.6 0.7 0.00069 18.9 0.0 3.1 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_21 PF09976.9 EGR32964.1 - 5e-06 26.4 2.2 0.085 12.6 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat-like domain DUF627 PF04781.12 EGR32964.1 - 0.00042 20.3 5.1 0.0081 16.2 0.2 3.7 3 1 0 3 3 3 1 Protein of unknown function (DUF627) TPR_MalT PF17874.1 EGR32964.1 - 0.00044 19.7 1.0 0.11 11.8 0.2 3.4 1 1 0 2 2 2 1 MalT-like TPR region TOM20_plant PF06552.12 EGR32964.1 - 0.00065 19.5 12.6 0.33 10.7 0.1 5.9 2 1 3 6 6 6 1 Plant specific mitochondrial import receptor subunit TOM20 FAT PF02259.23 EGR32964.1 - 0.00098 18.4 10.5 0.0022 17.2 0.8 3.2 2 1 1 3 3 3 1 FAT domain ChAPs PF09295.10 EGR32964.1 - 0.0012 18.0 7.0 0.79 8.7 0.1 3.6 1 1 2 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) SHNi-TPR PF10516.9 EGR32964.1 - 0.057 12.9 0.1 0.057 12.9 0.1 4.3 6 0 0 6 6 6 0 SHNi-TPR DUF3805 PF12712.7 EGR32964.1 - 0.22 11.6 4.1 0.84 9.8 1.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF3805) BTAD PF03704.17 EGR32964.1 - 0.26 11.7 1.1 5.1 7.5 0.0 3.0 4 1 0 4 4 3 0 Bacterial transcriptional activator domain Rapsyn_N PF10579.9 EGR32964.1 - 0.95 9.6 7.8 41 4.4 0.0 4.3 2 1 3 5 5 5 0 Rapsyn N-terminal myristoylation and linker region Guanylate_cyc PF00211.20 EGR32965.1 - 1.8e-46 158.1 1.8 2.2e-46 157.8 1.8 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain RPW8 PF05659.11 EGR32965.1 - 0.013 15.2 0.6 0.099 12.3 0.1 2.2 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Guanylate_cyc PF00211.20 EGR32966.1 - 1.6e-35 122.4 0.6 2.1e-35 122.0 0.6 1.1 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Imm12 PF15560.6 EGR32966.1 - 0.045 13.7 1.5 0.047 13.6 0.5 1.5 2 0 0 2 2 2 0 Immunity protein 12 PhoLip_ATPase_C PF16212.5 EGR32967.1 - 3.4e-33 115.5 32.2 3.4e-33 115.5 32.2 4.7 4 1 1 5 5 5 1 Phospholipid-translocating P-type ATPase C-terminal E1-E2_ATPase PF00122.20 EGR32967.1 - 0.00021 20.9 0.5 0.00021 20.9 0.5 3.1 3 2 1 4 4 4 1 E1-E2 ATPase PhoLip_ATPase_N PF16209.5 EGR32967.1 - 0.0012 18.4 5.2 0.0012 18.4 5.2 3.8 4 0 0 4 4 4 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGR32967.1 - 0.077 13.1 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 Cation transport ATPase (P-type) MSC PF09402.10 EGR32967.1 - 3.9 6.8 7.8 0.52 9.7 2.7 2.1 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain Ion_trans PF00520.31 EGR32968.1 - 0.0021 17.3 15.5 0.0021 17.3 15.5 3.0 1 1 2 3 3 3 1 Ion transport protein RIH_assoc PF08454.11 EGR32969.1 - 1.1e-36 124.7 12.6 1.1e-36 124.7 12.6 6.5 4 2 1 5 5 5 2 RyR and IP3R Homology associated Ins145_P3_rec PF08709.11 EGR32970.1 - 5.1e-17 61.8 6.6 5.3e-15 55.2 2.8 2.6 2 0 0 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 EGR32970.1 - 8e-09 35.6 0.3 8e-09 35.6 0.3 3.7 2 1 1 3 3 3 1 MIR domain RYDR_ITPR PF01365.21 EGR32970.1 - 5.9e-08 32.4 36.8 1.9e-07 30.7 1.7 5.5 3 1 1 4 4 4 2 RIH domain Peptidase_C2 PF00648.21 EGR32971.1 - 6.7e-70 235.5 3.0 1.1e-69 234.7 3.0 1.4 1 0 0 1 1 1 1 Calpain family cysteine protease Baculo_LEF-10 PF07206.11 EGR32971.1 - 3.2 8.0 5.2 7.4 6.8 0.4 3.3 4 0 0 4 4 4 0 Baculovirus late expression factor 10 (LEF-10) Pkinase PF00069.25 EGR32974.1 - 5.6e-13 48.9 1.2 5.6e-13 48.9 1.2 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32974.1 - 1.1e-07 31.4 1.2 1.3e-07 31.2 1.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_M14 PF00246.24 EGR32975.1 - 5.3e-17 62.5 0.0 1.9e-16 60.7 0.0 1.9 1 1 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 EGR32975.1 - 0.0028 16.8 0.0 0.0043 16.2 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF3450 PF11932.8 EGR32978.1 - 0.0061 15.9 4.0 0.0061 15.9 4.0 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF3450) Exonuc_VII_L PF02601.15 EGR32978.1 - 1 8.9 17.6 1.3 8.5 17.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Spc7 PF08317.11 EGR32978.1 - 2.6 6.8 29.8 5.7 5.7 29.8 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein HIP1_clath_bdg PF16515.5 EGR32978.1 - 3.3 8.4 27.0 2.9 8.6 4.8 2.5 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 4HB_MCP_1 PF12729.7 EGR32978.1 - 4.9 6.7 24.1 0.52 9.8 17.4 2.3 1 1 1 2 2 2 0 Four helix bundle sensory module for signal transduction DUF883 PF05957.13 EGR32978.1 - 7.2 7.3 7.6 20 5.9 5.3 2.4 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) CN_hydrolase PF00795.22 EGR32979.1 - 8.8e-59 199.0 0.0 1.7e-58 198.1 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Amidohydro_1 PF01979.20 EGR32979.1 - 5.4e-25 88.4 0.0 1.3e-24 87.1 0.0 1.7 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGR32979.1 - 3.8e-11 43.1 0.0 0.0002 21.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family HMMR_N PF15905.5 EGR32979.1 - 0.89 9.0 8.4 1.6 8.1 8.4 1.4 1 1 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Glyoxalase PF00903.25 EGR32980.1 - 9.8e-09 35.5 0.1 4.6e-08 33.3 0.1 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGR32980.1 - 0.00032 21.0 0.0 0.0012 19.1 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EGR32980.1 - 0.035 14.0 0.0 6.4 6.7 0.0 2.5 2 0 0 2 2 2 0 Glyoxalase-like domain Phytoreo_S7 PF07236.11 EGR32980.1 - 0.14 10.5 0.0 0.19 10.1 0.0 1.1 1 0 0 1 1 1 0 Phytoreovirus S7 protein UCH PF00443.29 EGR32981.1 - 1.5e-70 237.6 5.2 1.5e-70 237.6 5.2 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR32981.1 - 3e-08 33.6 42.4 0.0001 22.1 7.5 3.8 2 1 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-MYND PF01753.18 EGR32981.1 - 0.0042 17.1 13.6 0.0042 17.1 13.6 3.5 4 0 0 4 4 4 1 MYND finger IBN_N PF03810.19 EGR32982.1 - 1.4e-09 37.8 0.7 1.4e-09 37.8 0.7 4.4 4 0 0 4 4 4 2 Importin-beta N-terminal domain PNPase PF03726.14 EGR32982.1 - 0.099 13.1 1.5 0.5 10.9 0.1 3.0 2 0 0 2 2 2 0 Polyribonucleotide nucleotidyltransferase, RNA binding domain Pkinase PF00069.25 EGR32983.1 - 6.2e-71 238.8 2.0 1e-70 238.1 2.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR32983.1 - 2.9e-46 157.9 0.3 6.3e-46 156.7 0.3 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR32983.1 - 4.8e-05 22.8 0.8 0.15 11.4 0.3 2.9 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EGR32983.1 - 0.00059 18.7 0.8 0.00084 18.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGR32983.1 - 0.0036 16.7 0.1 0.0065 15.9 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGR32983.1 - 0.039 13.6 0.2 0.086 12.5 0.2 1.7 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 TbpB_C PF17483.2 EGR32983.1 - 0.28 11.6 2.6 1 9.8 0.6 2.5 2 0 0 2 2 2 0 C-lobe handle domain of Tf-binding protein B Peptidase_M14 PF00246.24 EGR32984.1 - 2.1e-37 129.5 0.8 2.7e-37 129.1 0.8 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase DENN PF02141.21 EGR32985.1 - 1.2e-19 71.0 3.0 1.4e-19 70.8 3.0 1.1 1 0 0 1 1 1 1 DENN (AEX-3) domain Orai-1 PF07856.12 EGR32985.1 - 0.0019 17.9 0.4 0.003 17.3 0.4 1.2 1 0 0 1 1 1 1 Mediator of CRAC channel activity Tcp10_C PF07202.13 EGR32985.1 - 0.083 12.8 0.1 0.12 12.4 0.1 1.2 1 0 0 1 1 1 0 T-complex protein 10 C-terminus GETHR PF05671.11 EGR32987.1 - 4.5 6.7 16.4 1.5 8.2 0.2 4.1 5 0 0 5 5 5 0 GETHR pentapeptide repeat (5 copies) DUF1681 PF07933.14 EGR32988.1 - 6e-30 103.9 0.0 7.6e-30 103.6 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) CRPV_capsid PF08762.10 EGR32990.1 - 0.48 10.1 3.5 0.34 10.5 1.3 1.8 1 1 0 1 1 1 0 CRPV capsid protein like TSC22 PF01166.18 EGR32990.1 - 3.9 7.8 17.9 0.15 12.4 4.0 3.5 3 1 1 4 4 4 0 TSC-22/dip/bun family NTP_transf_2 PF01909.23 EGR32991.1 - 7.3e-09 35.8 0.2 2.7e-08 34.0 0.2 2.0 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EGR32991.1 - 0.0008 19.5 0.2 0.0021 18.1 0.2 1.8 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase PAP_assoc PF03828.19 EGR32991.1 - 0.0014 18.8 0.1 0.0014 18.8 0.1 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase Alba PF01918.21 EGR32992.1 - 0.0017 18.1 2.1 0.0024 17.7 2.1 1.2 1 0 0 1 1 1 1 Alba SpoVS PF04232.12 EGR32992.1 - 0.024 14.3 1.6 0.032 14.0 1.6 1.2 1 0 0 1 1 1 0 Stage V sporulation protein S (SpoVS) HU-CCDC81_bac_1 PF18174.1 EGR32992.1 - 0.14 12.0 0.0 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 CCDC81-like prokaryotic HU domain 1 HTH_Crp_2 PF13545.6 EGR32992.1 - 0.17 11.9 2.2 5.3 7.1 0.2 2.4 3 0 0 3 3 3 0 Crp-like helix-turn-helix domain Rpp20 PF12328.8 EGR32992.1 - 0.28 11.1 6.5 0.094 12.7 3.3 1.7 1 1 1 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P LUC7 PF03194.15 EGR32992.1 - 0.65 9.6 7.0 0.77 9.4 7.0 1.1 1 0 0 1 1 1 0 LUC7 N_terminus DAGK_acc PF00609.19 EGR32993.1 - 1.2e-37 129.8 0.3 1.8e-37 129.1 0.3 1.3 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 EGR32993.1 - 7.2e-08 32.1 0.3 1.9e-07 30.7 0.0 1.9 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain PAP_central PF04928.17 EGR32994.1 - 2.7e-62 210.0 0.6 4.1e-62 209.4 0.6 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EGR32994.1 - 9.2e-11 41.7 12.7 1.4e-09 37.8 0.2 3.3 2 1 1 3 3 3 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EGR32994.1 - 5.7e-05 23.3 1.1 0.0002 21.6 0.0 2.4 2 1 1 3 3 3 1 Nucleotidyltransferase domain FSH1 PF03959.13 EGR32994.1 - 0.0096 15.6 0.7 0.016 14.9 0.0 1.6 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Chorein_N PF12624.7 EGR32995.1 - 1.2e-22 80.2 6.4 1.2e-22 80.2 6.4 6.1 7 0 0 7 7 7 3 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 EGR32997.1 - 1.8e-49 167.9 5.9 1.8e-49 167.9 5.9 4.8 6 0 0 6 6 6 1 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 EGR32997.1 - 0.022 15.1 0.0 0.097 13.0 0.0 2.2 1 0 0 1 1 1 0 Autophagy-related protein C terminal domain Csm1_N PF18504.1 EGR32998.1 - 0.077 13.3 15.7 0.094 13.1 1.9 3.8 2 2 2 4 4 4 0 Csm1 N-terminal domain E1_UFD PF09358.10 EGR32998.1 - 1.1 10.0 6.5 0.22 12.2 1.0 2.3 2 1 0 2 2 2 0 Ubiquitin fold domain TB2_DP1_HVA22 PF03134.19 EGR32999.1 - 2.6e-25 88.2 5.7 4.2e-25 87.5 5.7 1.3 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Vint PF14623.6 EGR33000.1 - 4.2e-38 130.8 0.0 7.9e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 Hint-domain Vwaint PF14624.6 EGR33000.1 - 1.2e-20 73.4 0.0 3.7e-20 71.8 0.0 1.9 1 0 0 1 1 1 1 VWA / Hh protein intein-like VWA_2 PF13519.6 EGR33000.1 - 4.5e-16 59.4 0.1 2.3e-15 57.2 0.1 2.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EGR33000.1 - 1.5e-15 57.9 0.5 5e-15 56.2 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 EGR33000.1 - 2.1e-06 27.8 0.0 2.1e-05 24.5 0.0 2.3 1 1 0 1 1 1 1 von Willebrand factor type A domain Hint PF01079.20 EGR33000.1 - 0.012 15.1 0.1 0.049 13.1 0.1 1.9 1 1 0 2 2 2 0 Hint module VWA_CoxE PF05762.14 EGR33000.1 - 0.051 13.0 0.0 0.71 9.2 0.0 2.1 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein RRM_1 PF00076.22 EGR33003.1 - 2e-12 46.8 0.0 2.7e-05 23.9 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MsyB PF13984.6 EGR33003.1 - 0.12 12.7 0.2 2 8.8 0.1 2.3 2 0 0 2 2 2 0 MsyB protein Limkain-b1 PF11608.8 EGR33003.1 - 0.13 12.3 0.0 1.3 9.1 0.0 2.2 2 0 0 2 2 2 0 Limkain b1 RBM39linker PF15519.6 EGR33003.1 - 0.48 11.5 1.8 1.5 10.0 1.8 2.0 1 1 0 1 1 1 0 linker between RRM2 and RRM3 domains in RBM39 protein Pkinase PF00069.25 EGR33004.1 - 5.4e-06 26.0 0.0 5.4e-06 26.0 0.0 2.3 2 1 0 2 2 2 1 Protein kinase domain Sin_N PF04801.13 EGR33004.1 - 0.41 9.8 13.8 0.47 9.6 13.8 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Pkinase PF00069.25 EGR33005.1 - 2.2e-43 148.6 0.6 7.8e-43 146.7 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33005.1 - 1.2e-19 70.6 0.1 4.2e-11 42.6 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Kdo PF06293.14 EGR33005.1 - 0.014 14.8 0.0 0.032 13.6 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family TMEM154 PF15102.6 EGR33005.1 - 0.057 13.3 8.5 0.12 12.2 8.5 1.5 1 0 0 1 1 1 0 TMEM154 protein family Shisa PF13908.6 EGR33005.1 - 0.075 13.3 2.3 0.13 12.5 2.3 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Orf78 PF06024.12 EGR33005.1 - 0.11 12.8 15.3 0.031 14.6 9.8 2.4 2 0 0 2 2 2 0 Orf78 (ac78) Claudin_2 PF13903.6 EGR33005.1 - 0.17 11.6 1.2 0.34 10.6 1.2 1.4 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction RIFIN PF02009.16 EGR33005.1 - 0.42 10.5 14.7 0.67 9.8 14.7 1.3 1 0 0 1 1 1 0 Rifin PRA1 PF03208.19 EGR33005.1 - 1.6 8.3 7.6 0.3 10.7 3.0 1.9 2 0 0 2 2 2 0 PRA1 family protein Cytochrom_C PF00034.21 EGR33006.1 - 0.00055 21.0 0.3 0.0016 19.5 0.3 1.8 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EGR33006.1 - 0.00058 20.1 0.7 0.00077 19.7 0.7 1.5 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Pkinase PF00069.25 EGR33007.1 - 5e-69 232.6 0.4 6.2e-69 232.3 0.4 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33007.1 - 1.5e-35 122.7 0.0 2e-35 122.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR33007.1 - 0.0001 21.4 0.4 0.00022 20.3 0.4 1.6 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGR33007.1 - 0.00013 21.4 0.0 0.00026 20.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR33007.1 - 0.00075 18.4 0.0 0.0011 17.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EGR33007.1 - 0.0039 16.3 0.0 0.0068 15.5 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 EGR33007.1 - 0.048 13.0 0.1 0.08 12.3 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGR33007.1 - 0.05 13.2 0.1 0.084 12.5 0.1 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EGR33007.1 - 0.052 13.5 0.0 0.082 12.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EGR33007.1 - 0.18 11.4 2.1 0.5 10.0 0.2 2.4 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 SHIPPO-rpt PF07004.12 EGR33008.1 - 0.00016 22.4 15.8 0.79 10.8 0.6 5.6 6 0 0 6 6 6 3 Sperm-tail PG-rich repeat HSP90 PF00183.18 EGR33010.1 - 4.1e-95 319.6 22.2 2.4e-91 307.2 17.8 2.3 1 1 1 2 2 2 2 Hsp90 protein HATPase_c_3 PF13589.6 EGR33010.1 - 6.6e-10 39.0 0.5 1.6e-09 37.7 0.5 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGR33010.1 - 8.1e-07 29.5 1.2 3e-06 27.7 1.2 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase UvsY PF11056.8 EGR33010.1 - 0.028 14.8 1.7 0.067 13.5 0.3 2.4 2 0 0 2 2 2 0 Recombination, repair and ssDNA binding protein UvsY CsgF PF10614.9 EGR33010.1 - 1.8 8.8 7.5 0.25 11.6 2.4 2.2 2 0 0 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein Pkinase PF00069.25 EGR33011.1 - 1.4e-18 67.2 0.0 1.4e-18 67.2 0.0 3.1 3 2 1 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33011.1 - 8.1e-11 41.7 1.1 3.5e-10 39.6 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase UTP15_C PF09384.10 EGR33011.1 - 0.012 15.3 0.0 0.033 13.9 0.0 1.8 1 0 0 1 1 1 0 UTP15 C terminal SAB PF04382.13 EGR33012.1 - 0.17 12.0 4.0 2.4 8.3 2.2 2.9 2 0 0 2 2 2 0 SAB domain HrpB7 PF09486.10 EGR33012.1 - 3.7 7.9 8.8 3.7 7.9 5.2 2.5 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) ADK PF00406.22 EGR33013.1 - 7e-46 156.1 0.0 9e-46 155.7 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGR33013.1 - 1.4e-32 112.9 0.0 2.1e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGR33013.1 - 8.4e-10 39.3 0.1 1.4e-09 38.6 0.1 1.3 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGR33013.1 - 1.6e-06 27.9 0.9 0.0036 17.0 0.4 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.6 EGR33013.1 - 9.3e-06 25.9 0.0 2.2e-05 24.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain dNK PF01712.19 EGR33013.1 - 0.001 18.9 0.6 0.002 18.0 0.6 1.5 1 0 0 1 1 1 1 Deoxynucleoside kinase HEAT PF02985.22 EGR33015.1 - 0.11 12.9 0.0 1.4 9.4 0.0 2.5 2 0 0 2 2 2 0 HEAT repeat BET PF17035.5 EGR33015.1 - 0.11 12.7 0.2 0.58 10.4 0.0 2.1 2 0 0 2 2 2 0 Bromodomain extra-terminal - transcription regulation DUF2816 PF10992.8 EGR33016.1 - 1.4e-24 85.7 22.3 1.4e-24 85.7 22.3 4.9 4 2 0 4 4 4 2 Protein of unknown function (DUF2816) O-antigen_lig PF13425.6 EGR33016.1 - 4.3 6.0 4.9 6.7 5.4 4.9 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein RRM_DME PF15628.6 EGR33018.1 - 0.06 13.5 0.4 0.12 12.6 0.4 1.4 1 0 0 1 1 1 0 RRM in Demeter Ras PF00071.22 EGR33019.1 - 1.6e-51 174.1 0.3 1.6e-51 174.1 0.3 2.8 3 0 0 3 3 3 1 Ras family Pkinase PF00069.25 EGR33019.1 - 4.8e-49 167.1 12.0 2.2e-36 125.6 6.1 2.7 2 1 0 2 2 2 2 Protein kinase domain Roc PF08477.13 EGR33019.1 - 6.5e-30 103.8 3.4 1.6e-29 102.5 0.1 3.1 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Pkinase_Tyr PF07714.17 EGR33019.1 - 2.2e-25 89.4 11.8 3.7e-13 49.4 1.9 3.7 3 1 1 4 4 4 3 Protein tyrosine kinase Arf PF00025.21 EGR33019.1 - 1.6e-15 57.0 2.1 4.2e-15 55.6 1.2 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family Kinase-like PF14531.6 EGR33019.1 - 1.2e-06 28.0 0.9 4.2e-06 26.3 0.9 1.9 1 1 0 1 1 1 1 Kinase-like MMR_HSR1 PF01926.23 EGR33019.1 - 0.00015 21.9 4.8 0.00035 20.6 0.1 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase TniB PF05621.11 EGR33019.1 - 0.00056 19.4 0.2 0.0028 17.1 0.0 2.2 2 0 0 2 2 2 1 Bacterial TniB protein AAA_16 PF13191.6 EGR33019.1 - 0.00095 19.6 0.3 0.53 10.6 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_7 PF12775.7 EGR33019.1 - 0.0032 17.0 3.6 0.047 13.2 0.0 3.2 3 0 0 3 3 3 1 P-loop containing dynein motor region Kdo PF06293.14 EGR33019.1 - 0.0033 16.8 0.3 0.0085 15.5 0.3 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR33019.1 - 0.0082 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family GTP_EFTU PF00009.27 EGR33019.1 - 0.0083 15.7 0.1 0.0083 15.7 0.1 2.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain INSC_LBD PF16748.5 EGR33019.1 - 0.067 12.7 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Inscuteable LGN-binding domain AAA_22 PF13401.6 EGR33019.1 - 0.19 12.0 0.9 1.8 8.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF2457 PF10446.9 EGR33019.1 - 0.22 10.6 12.0 0.36 9.9 12.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RsgA_GTPase PF03193.16 EGR33019.1 - 0.66 9.9 6.0 2 8.3 0.0 3.1 4 0 0 4 4 3 0 RsgA GTPase BUD22 PF09073.10 EGR33019.1 - 5.6 6.2 21.5 0.064 12.6 13.5 1.8 2 0 0 2 2 2 0 BUD22 DSPc PF00782.20 EGR33021.1 - 2.3e-09 37.2 0.6 6.2e-09 35.8 0.6 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGR33021.1 - 0.1 12.5 0.0 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 EGR33022.1 - 5.3e-23 81.3 0.3 5.3e-23 81.3 0.3 4.8 2 1 1 3 3 3 1 Dual specificity phosphatase, catalytic domain GalKase_gal_bdg PF10509.9 EGR33022.1 - 4.8e-18 64.5 0.0 9.9e-18 63.4 0.0 1.6 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 EGR33022.1 - 2.4e-14 53.5 0.0 1.4e-13 51.0 0.0 2.4 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 EGR33022.1 - 2.6e-07 30.8 0.1 4.7e-07 29.9 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain Init_tRNA_PT PF04179.12 EGR33022.1 - 0.00075 19.8 0.3 0.00075 19.8 0.3 3.2 2 1 0 2 2 2 1 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 EGR33022.1 - 9.8 6.3 0.0 9.8 6.3 0.0 6.0 3 1 0 3 3 3 0 Inositol hexakisphosphate EF-hand_1 PF00036.32 EGR33024.1 - 2.3e-10 39.3 0.1 0.00016 21.0 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGR33024.1 - 3.2e-09 36.0 0.1 0.0019 18.0 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EGR33024.1 - 8.6e-09 35.7 2.6 5.6e-06 26.7 0.2 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGR33024.1 - 2.1e-07 30.1 0.9 0.0022 17.4 0.1 2.9 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGR33024.1 - 4.8e-07 29.5 0.1 0.0013 18.5 0.1 2.4 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGR33024.1 - 0.046 14.1 0.9 0.14 12.5 0.1 1.9 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Mak10 PF04112.13 EGR33025.1 - 0.00037 20.1 1.0 0.00056 19.5 1.0 1.3 1 0 0 1 1 1 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase C2 PF00168.30 EGR33026.1 - 4.8e-07 30.0 0.1 1.4e-06 28.6 0.0 1.7 1 1 0 2 2 2 1 C2 domain PEPCK_ATP PF01293.20 EGR33029.1 - 8.4e-215 713.8 0.0 9.8e-215 713.6 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_16 PF13191.6 EGR33029.1 - 0.12 12.7 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 EGR33029.1 - 0.15 12.2 0.0 0.41 10.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain VSP PF03302.13 EGR33030.1 - 2.2e-08 33.4 78.8 0.0018 17.2 32.7 3.6 1 1 2 3 3 3 3 Giardia variant-specific surface protein DUF667 PF05018.13 EGR33031.1 - 3.9e-16 59.3 0.6 3.9e-16 59.3 0.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF667) Pkinase PF00069.25 EGR33032.1 - 1.1e-60 205.3 0.0 1.4e-60 204.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33032.1 - 4.1e-31 108.2 0.0 5.7e-31 107.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33032.1 - 8.8e-05 22.0 0.0 0.00012 21.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR33032.1 - 0.00044 19.1 0.0 0.00058 18.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EGR33032.1 - 0.0019 17.3 0.0 0.0039 16.3 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Yip1 PF04893.17 EGR33033.1 - 6.7e-13 48.7 15.1 1.3e-12 47.8 15.0 1.5 1 1 0 1 1 1 1 Yip1 domain Pkinase PF00069.25 EGR33034.1 - 2.5e-56 191.0 0.8 3.2e-56 190.6 0.8 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33034.1 - 5.7e-31 107.7 0.0 7.5e-31 107.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33034.1 - 4.1e-08 32.9 0.1 0.00031 20.2 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EGR33034.1 - 0.015 14.1 0.9 0.85 8.3 0.1 2.1 1 1 1 2 2 2 0 Fungal protein kinase Annexin_like PF18411.1 EGR33034.1 - 0.023 14.9 0.1 0.074 13.3 0.1 1.8 1 0 0 1 1 1 0 Annexin-like domain Kdo PF06293.14 EGR33034.1 - 0.034 13.5 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4488 PF14869.6 EGR33034.1 - 0.069 13.1 2.1 0.13 12.2 2.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) TBK1_ULD PF18396.1 EGR33035.1 - 0.014 15.3 1.9 0.014 15.3 1.9 1.9 1 1 1 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain PDEase_I PF00233.19 EGR33036.1 - 2.9e-31 109.0 7.7 6.7e-17 62.0 3.8 3.0 2 1 1 3 3 3 2 3'5'-cyclic nucleotide phosphodiesterase GrpE PF01025.19 EGR33036.1 - 0.0046 16.6 0.5 0.0067 16.1 0.5 1.2 1 0 0 1 1 1 1 GrpE CitX PF03802.14 EGR33036.1 - 0.076 12.8 0.1 1.7 8.4 0.1 2.1 2 0 0 2 2 2 0 Apo-citrate lyase phosphoribosyl-dephospho-CoA transferase CxC4 PF18717.1 EGR33036.1 - 0.17 11.7 1.5 0.95 9.3 0.3 2.1 1 1 1 2 2 2 0 CxC4 like cysteine cluster associated with KDZ transposases MORN PF02493.20 EGR33037.1 - 2e-21 74.5 25.7 7.4e-06 25.5 1.0 6.0 6 0 0 6 6 6 5 MORN repeat MORN_2 PF07661.13 EGR33037.1 - 0.059 13.6 7.5 0.43 10.9 0.8 4.4 3 1 0 3 3 3 0 MORN repeat variant DUF5517 PF17639.2 EGR33037.1 - 0.089 13.1 2.1 0.18 12.1 2.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5517) DUF3048_C PF17479.2 EGR33037.1 - 2.1 8.8 14.6 2.5 8.5 0.4 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3048) C-terminal domain ASH PF15780.5 EGR33038.1 - 8.5e-17 61.2 1.3 5.7e-05 23.2 0.0 6.5 7 0 0 7 7 7 4 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 EGR33038.1 - 0.025 14.7 0.0 25 5.1 0.0 4.0 4 0 0 4 4 4 0 Flagellar-associated PapD-like Mem_trans PF03547.18 EGR33038.1 - 0.12 10.8 0.8 0.22 9.9 0.8 1.5 1 0 0 1 1 1 0 Membrane transport protein EPL1 PF10513.9 EGR33038.1 - 0.67 10.3 24.2 0.13 12.6 11.1 3.4 3 0 0 3 3 3 0 Enhancer of polycomb-like DDHD PF02862.17 EGR33038.1 - 2 8.5 9.8 1.2 9.2 5.3 2.6 3 0 0 3 3 3 0 DDHD domain DUF4407 PF14362.6 EGR33038.1 - 9.6 5.5 19.4 0.5 9.7 12.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HlyIII PF03006.20 EGR33039.1 - 1.2e-46 159.3 23.6 6.3e-46 156.9 23.6 1.9 1 1 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 EGR33039.1 - 0.0093 16.0 0.1 0.37 10.9 0.0 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF962) Phasin PF05597.11 EGR33039.1 - 0.08 13.0 0.8 0.43 10.6 0.0 2.2 2 0 0 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) CdvA PF18822.1 EGR33039.1 - 0.55 10.1 7.3 2.2 8.1 0.1 3.0 3 0 0 3 3 3 0 CdvA-like coiled-coil domain Baculo_PEP_C PF04513.12 EGR33039.1 - 1 9.4 9.1 0.16 12.0 0.7 3.0 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Csm2_III-A PF03750.13 EGR33039.1 - 2.2 9.2 7.3 0.88 10.4 4.1 2.0 2 1 0 2 2 2 0 Csm2 Type III-A HEAT PF02985.22 EGR33040.1 - 1.6e-07 31.0 0.0 0.09 13.1 0.0 4.9 7 0 0 7 7 7 2 HEAT repeat 3H PF02829.14 EGR33040.1 - 0.0098 16.2 1.8 0.032 14.5 0.3 2.6 3 0 0 3 3 3 1 3H domain RIX1 PF08167.12 EGR33040.1 - 0.041 13.6 3.6 0.14 11.9 0.7 2.7 2 2 1 3 3 3 0 rRNA processing/ribosome biogenesis TPR_12 PF13424.6 EGR33041.1 - 0.0022 18.2 4.8 0.0075 16.5 0.3 3.5 3 1 1 4 4 4 2 Tetratricopeptide repeat Cas9_PI2 PF18070.1 EGR33041.1 - 0.069 13.9 0.0 0.069 13.9 0.0 7.5 7 2 1 8 8 8 0 CRISPR-Cas9 PI domain Terminase_6C PF17289.2 EGR33041.1 - 2 8.5 5.0 2.2 8.4 1.7 2.7 2 0 0 2 2 2 0 Terminase RNaseH-like domain TPR_2 PF07719.17 EGR33041.1 - 2.4 8.5 11.5 7.6 6.9 0.4 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Swi6_N PF18530.1 EGR33042.1 - 0.063 13.4 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Swi6 N-terminal domain Pur_ac_phosph_N PF16656.5 EGR33042.1 - 0.076 13.6 0.0 0.14 12.8 0.0 1.3 1 0 0 1 1 1 0 Purple acid Phosphatase, N-terminal domain fn3 PF00041.21 EGR33042.1 - 0.18 12.2 0.0 0.35 11.2 0.0 1.5 1 0 0 1 1 1 0 Fibronectin type III domain Ion_trans PF00520.31 EGR33043.1 - 5.9e-39 133.8 71.0 3.3e-23 82.2 28.6 3.2 3 0 0 3 3 3 2 Ion transport protein Pkinase PF00069.25 EGR33044.1 - 5.5e-59 199.7 3.3 6.3e-59 199.5 3.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33044.1 - 3.5e-37 128.1 0.6 4.1e-37 127.9 0.6 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR33044.1 - 2e-06 27.4 1.8 2.3e-06 27.1 1.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGR33044.1 - 0.0038 16.2 2.0 0.0052 15.8 2.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 EGR33044.1 - 0.014 15.0 1.1 0.03 13.9 0.2 1.8 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGR33044.1 - 0.025 13.4 0.1 0.025 13.4 0.1 1.5 2 0 0 2 2 2 0 Fungal protein kinase Kri1_C PF12936.7 EGR33044.1 - 0.082 13.1 0.1 0.19 12.0 0.1 1.6 1 0 0 1 1 1 0 KRI1-like family C-terminal RNA_pol_Rpb1_5 PF04998.17 EGR33044.1 - 2.5 7.5 3.9 2.9 7.3 3.1 1.4 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Phage_GP20 PF06810.11 EGR33045.1 - 0.016 15.1 3.2 0.023 14.5 3.2 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 Pkinase PF00069.25 EGR33046.1 - 1.7e-31 109.5 0.1 2e-31 109.3 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33046.1 - 5.1e-13 48.9 0.0 6.1e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Sec3-PIP2_bind PF15277.6 EGR33046.1 - 0.077 13.1 0.6 0.85 9.8 0.0 2.6 2 1 0 2 2 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH AAA_25 PF13481.6 EGR33048.1 - 2.6e-20 72.8 0.0 2.3e-19 69.7 0.0 2.0 2 0 0 2 2 2 1 AAA domain Toprim_2 PF13155.6 EGR33048.1 - 1.6e-09 38.0 0.0 5e-09 36.5 0.0 1.9 2 0 0 2 2 1 1 Toprim-like Toprim_3 PF13362.6 EGR33048.1 - 7.5e-09 35.8 0.0 5.7e-07 29.8 0.0 2.4 2 0 0 2 2 2 1 Toprim domain AAA_22 PF13401.6 EGR33048.1 - 2.7e-08 34.2 0.1 1.2e-07 32.1 0.1 2.0 1 1 0 1 1 1 1 AAA domain ATPase PF06745.13 EGR33048.1 - 1.8e-07 30.7 0.0 4.5e-07 29.5 0.0 1.6 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 EGR33048.1 - 2.4e-07 30.4 0.0 4.7e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain Toprim_4 PF13662.6 EGR33048.1 - 1.7e-05 25.2 0.0 0.00032 21.1 0.0 2.9 3 1 0 3 3 3 1 Toprim domain AAA_29 PF13555.6 EGR33048.1 - 0.00043 20.0 0.1 0.0013 18.4 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SSE PF00437.20 EGR33048.1 - 0.00067 18.8 0.0 0.0011 18.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein ABC_tran PF00005.27 EGR33048.1 - 0.0014 19.2 0.2 0.004 17.7 0.0 1.8 2 0 0 2 2 1 1 ABC transporter cobW PF02492.19 EGR33048.1 - 0.0076 15.9 0.3 0.018 14.6 0.0 1.8 2 0 0 2 2 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EGR33048.1 - 0.011 16.3 0.1 0.049 14.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain VirE PF05272.11 EGR33048.1 - 0.016 15.0 0.1 0.048 13.4 0.0 1.8 1 1 0 1 1 1 0 Virulence-associated protein E AAA_16 PF13191.6 EGR33048.1 - 0.016 15.6 0.0 0.03 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain SMC_N PF02463.19 EGR33048.1 - 0.017 14.6 0.8 0.08 12.4 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 EGR33048.1 - 0.023 14.6 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RsgA_GTPase PF03193.16 EGR33048.1 - 0.037 13.9 2.9 0.058 13.3 0.1 2.4 2 2 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 EGR33048.1 - 0.056 13.2 0.1 0.16 11.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EGR33048.1 - 0.058 12.8 0.1 0.19 11.1 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein DUF2188 PF09954.9 EGR33048.1 - 0.059 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2188) AAA_19 PF13245.6 EGR33048.1 - 0.062 13.6 0.1 1.8 8.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGR33048.1 - 0.071 12.8 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGR33048.1 - 0.084 13.1 0.0 0.21 11.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain TsaE PF02367.17 EGR33048.1 - 0.1 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_21 PF13304.6 EGR33048.1 - 0.11 12.3 3.7 0.081 12.7 1.1 2.1 2 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF835 PF05763.12 EGR33048.1 - 0.11 12.2 1.9 0.15 11.8 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF835) DUF853 PF05872.12 EGR33048.1 - 0.12 10.9 0.1 0.31 9.6 0.0 1.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) IstB_IS21 PF01695.17 EGR33048.1 - 0.13 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 EGR33048.1 - 0.18 12.0 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGR33048.1 - 0.3 11.1 3.2 0.41 10.7 0.6 2.6 2 1 0 2 2 2 0 AAA domain RabGAP-TBC PF00566.18 EGR33049.1 - 1.3e-27 96.8 35.0 1.2e-25 90.5 30.9 3.3 1 1 1 2 2 2 1 Rab-GTPase-TBC domain Prenyltrans PF00432.21 EGR33050.1 - 1.6e-61 203.7 9.3 2.1e-12 46.5 0.0 6.3 7 0 0 7 7 7 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EGR33050.1 - 1.6e-08 34.0 0.5 0.00069 18.8 0.0 2.5 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EGR33050.1 - 0.00021 20.5 0.1 0.046 12.8 0.0 3.2 1 1 3 4 4 4 2 Squalene-hopene cyclase N-terminal domain DUF2326 PF10088.9 EGR33050.1 - 0.12 12.1 0.0 0.45 10.3 0.0 1.9 2 0 0 2 2 2 0 Uncharacterised protein conserved in bacteria (DUF2326) EGF_CA PF07645.15 EGR33050.1 - 0.2 11.9 1.4 14 6.0 0.1 2.7 2 0 0 2 2 2 0 Calcium-binding EGF domain Pkinase PF00069.25 EGR33051.1 - 1.9e-57 194.6 3.0 2.7e-57 194.1 3.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33051.1 - 3.2e-40 138.0 0.5 4.4e-40 137.6 0.5 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR33051.1 - 2.4e-05 23.8 0.2 4.5e-05 22.9 0.2 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGR33051.1 - 3.3e-05 23.3 0.3 0.00014 21.3 0.3 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EGR33051.1 - 0.002 18.1 0.0 0.003 17.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGR33051.1 - 0.003 16.4 0.5 0.0072 15.1 0.3 1.5 1 1 0 2 2 2 1 Fungal protein kinase zf-TRM13_CCCH PF11722.8 EGR33051.1 - 0.058 13.2 0.3 6.8 6.6 0.0 2.8 2 0 0 2 2 2 0 CCCH zinc finger in TRM13 protein PglD_N PF17836.1 EGR33051.1 - 0.071 13.8 1.4 0.22 12.2 0.1 2.4 2 0 0 2 2 2 0 PglD N-terminal domain Haspin_kinase PF12330.8 EGR33051.1 - 0.29 10.0 8.3 0.02 13.8 2.8 1.9 2 1 0 2 2 2 0 Haspin like kinase domain Tim17 PF02466.19 EGR33052.1 - 0.0016 18.8 0.0 0.003 17.9 0.0 1.5 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family CK2S PF15011.6 EGR33054.1 - 1.4 8.8 9.0 0.086 12.7 2.8 2.2 3 0 0 3 3 3 0 Casein Kinase 2 substrate DUF3574 PF12098.8 EGR33054.1 - 3.9 7.3 5.2 6.3 6.6 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3574) PRE_C2HC PF07530.11 EGR33054.1 - 4.5 7.5 7.3 0.41 10.8 1.2 2.5 3 0 0 3 3 3 0 Associated with zinc fingers STT3 PF02516.14 EGR33055.1 - 2.9e-109 366.2 45.7 1.5e-108 363.8 45.7 1.8 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit SUI1 PF01253.22 EGR33056.1 - 4e-19 68.9 0.0 5.1e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 DUF1425 PF07233.12 EGR33056.1 - 0.1 12.5 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1425) DUF3134 PF11332.8 EGR33056.1 - 0.14 12.5 0.0 0.14 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3134) DUF2804 PF10974.8 EGR33057.1 - 8.3e-43 147.2 6.1 1.3e-31 110.4 1.6 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2804) V_ATPase_I PF01496.19 EGR33058.1 - 3.7e-181 604.0 21.1 4.1e-181 603.9 21.1 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family H_PPase PF03030.16 EGR33058.1 - 0.047 12.3 0.0 0.089 11.4 0.0 1.5 2 0 0 2 2 2 0 Inorganic H+ pyrophosphatase LMBR1 PF04791.16 EGR33059.1 - 2.8e-92 310.2 42.7 3.3e-92 310.0 42.7 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein RcbX PF02341.15 EGR33059.1 - 1.5 9.1 5.7 0.3 11.4 1.2 2.1 2 0 0 2 2 2 0 RbcX protein DUF3285 PF11688.8 EGR33059.1 - 1.9 8.5 5.1 0.52 10.3 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) SF3A3 PF16837.5 EGR33060.1 - 0.054 14.0 0.0 0.093 13.3 0.0 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 MORN PF02493.20 EGR33061.1 - 3.4e-57 187.1 76.4 2e-08 33.7 0.9 9.9 10 0 0 10 10 10 9 MORN repeat Ufm1 PF03671.14 EGR33063.1 - 1.2e-19 70.2 1.5 1.2e-19 70.2 0.4 1.6 2 0 0 2 2 2 1 Ubiquitin fold modifier 1 protein DUF3244 PF11589.8 EGR33063.1 - 0.0091 16.1 1.7 0.025 14.6 1.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3244) Vac14_Fab1_bd PF12755.7 EGR33064.1 - 0.024 15.2 8.2 0.52 10.9 0.0 4.9 4 2 2 6 6 6 0 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGR33064.1 - 0.031 14.3 0.1 0.031 14.3 0.1 5.3 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGR33064.1 - 0.072 13.4 0.1 33 5.1 0.0 3.7 4 0 0 4 4 4 0 HEAT repeat Transposase_22 PF02994.14 EGR33064.1 - 0.13 12.5 1.3 0.74 10.0 0.2 2.9 2 0 0 2 2 2 0 L1 transposable element RBD-like domain Pkinase PF00069.25 EGR33065.1 - 5.9e-37 127.5 0.4 6.9e-37 127.2 0.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33065.1 - 1.1e-23 83.9 0.0 1.2e-23 83.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR33065.1 - 9.2e-05 21.4 0.0 9.2e-05 21.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EGR33065.1 - 0.0016 18.0 0.1 0.002 17.7 0.1 1.2 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 EGR33065.1 - 0.041 13.2 0.0 0.068 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR33065.1 - 0.1 12.5 0.0 0.11 12.4 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ion_trans PF00520.31 EGR33066.1 - 0.002 17.4 33.0 0.0033 16.7 23.1 3.8 2 1 0 2 2 2 1 Ion transport protein Ins145_P3_rec PF08709.11 EGR33067.1 - 1.9e-17 63.2 3.1 2.8e-17 62.7 1.4 2.1 2 0 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor Pkinase PF00069.25 EGR33068.1 - 1.7e-52 178.4 0.2 1.7e-52 178.4 0.2 1.6 2 0 0 2 2 2 1 Protein kinase domain EF-hand_1 PF00036.32 EGR33068.1 - 4.3e-25 85.4 11.3 6.4e-07 28.5 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 EGR33068.1 - 2.7e-24 83.5 9.5 2.9e-06 26.5 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGR33068.1 - 3.7e-23 81.8 2.3 5.5e-10 39.6 0.4 3.4 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR33068.1 - 2.5e-22 76.9 8.3 1.4e-06 27.7 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain Pkinase_Tyr PF07714.17 EGR33068.1 - 4.6e-20 72.0 0.0 7.7e-20 71.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_8 PF13833.6 EGR33068.1 - 8.5e-18 64.0 7.8 0.00046 20.0 0.1 4.5 2 1 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGR33068.1 - 1.3e-10 41.6 2.0 5.9e-06 26.6 0.1 3.2 2 1 1 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.6 EGR33068.1 - 0.00017 21.0 0.3 0.0004 19.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGR33068.1 - 0.001 18.5 0.7 0.0017 17.7 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR33068.1 - 0.0024 16.7 0.0 0.0043 15.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR33068.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family EF-G-binding_N PF07299.11 EGR33068.1 - 0.063 13.8 5.2 0.1 13.1 2.4 2.6 2 1 0 2 2 2 0 Elongation factor G-binding protein, N-terminal Dockerin_1 PF00404.18 EGR33068.1 - 0.14 12.3 3.9 7.9 6.8 0.1 3.4 2 1 0 2 2 2 0 Dockerin type I domain Hydrolase_3 PF08282.12 EGR33069.1 - 0.75 9.5 10.8 0.97 9.1 10.8 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Pam16 PF03656.13 EGR33070.1 - 0.00018 21.5 0.0 0.00018 21.5 0.0 2.5 1 1 2 3 3 3 1 Pam16 SelP_N PF04592.14 EGR33070.1 - 0.00034 20.1 0.8 0.00038 20.0 0.8 1.2 1 0 0 1 1 1 1 Selenoprotein P, N terminal region TERB2 PF15101.6 EGR33070.1 - 0.27 11.3 11.8 0.39 10.8 10.7 1.8 2 0 0 2 2 2 0 Telomere-associated protein TERB2 ORC_WH_C PF18137.1 EGR33070.1 - 0.29 11.2 11.2 0.39 10.8 11.2 1.2 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal DDHD PF02862.17 EGR33070.1 - 0.36 11.0 6.3 0.44 10.7 6.3 1.2 1 0 0 1 1 1 0 DDHD domain SID-1_RNA_chan PF13965.6 EGR33070.1 - 1.2 7.5 5.1 1 7.7 5.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 GOLD_2 PF13897.6 EGR33070.1 - 6.9 7.2 10.2 13 6.3 10.2 1.5 1 1 0 1 1 1 0 Golgi-dynamics membrane-trafficking cNMP_binding PF00027.29 EGR33071.1 - 2.2e-13 50.1 0.0 3.4e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGR33071.1 - 7.7e-06 25.8 0.4 1.4e-05 25.0 0.4 1.4 1 0 0 1 1 1 1 Ion channel LIFR_N PF18207.1 EGR33071.1 - 0.042 14.2 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 Leukemia inhibitory factor receptor N-terminal domain Thioredoxin PF00085.20 EGR33072.1 - 1.7e-59 198.2 7.5 5.1e-32 109.9 0.0 3.7 4 0 0 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 EGR33072.1 - 2.7e-30 105.6 20.7 1e-21 77.7 9.0 3.5 3 1 1 4 4 4 3 Thioredoxin-like domain OST3_OST6 PF04756.13 EGR33072.1 - 1e-13 51.3 5.3 9.4e-07 28.5 0.0 3.2 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_7 PF13899.6 EGR33072.1 - 1.3e-12 47.7 0.2 1.5e-05 25.1 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EGR33072.1 - 7.8e-12 45.6 4.4 3.5e-05 24.2 0.1 4.7 4 2 0 4 4 4 2 Thioredoxin-like domain Calsequestrin PF01216.17 EGR33072.1 - 1.8e-06 27.3 12.5 3.5e-06 26.3 5.9 2.4 1 1 0 2 2 2 2 Calsequestrin Thioredoxin_8 PF13905.6 EGR33072.1 - 2.3e-06 27.9 13.5 0.011 16.0 0.2 6.5 3 3 3 6 6 6 2 Thioredoxin-like AhpC-TSA PF00578.21 EGR33072.1 - 4.5e-06 26.6 2.0 0.13 12.2 0.1 3.7 4 0 0 4 4 4 2 AhpC/TSA family Redoxin PF08534.10 EGR33072.1 - 6.9e-05 22.6 0.8 0.18 11.5 0.0 3.4 3 0 0 3 3 3 2 Redoxin Glutaredoxin PF00462.24 EGR33072.1 - 0.15 12.3 0.9 9.8 6.5 0.1 3.5 3 0 0 3 3 3 0 Glutaredoxin Ribosomal_L40e PF01020.17 EGR33072.1 - 0.78 9.7 3.5 29 4.7 0.7 3.2 2 1 1 3 3 3 0 Ribosomal L40e family Saf_2TM PF18303.1 EGR33074.1 - 0.013 15.1 1.7 0.016 14.8 1.7 1.3 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain Ins145_P3_rec PF08709.11 EGR33075.1 - 2.1e-06 27.1 2.6 1e-05 24.9 0.4 3.0 2 0 0 2 2 2 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 EGR33075.1 - 3.1e-06 27.2 10.5 0.00036 20.4 2.1 3.6 2 1 1 3 3 3 3 MIR domain OST_P2 PF18235.1 EGR33075.1 - 7.7 6.5 13.7 4 7.4 0.2 4.2 4 0 0 4 4 4 0 Oligosaccharyltransferase Peripheral 2 domain DUF4029 PF13221.6 EGR33076.1 - 0.013 16.2 8.5 0.022 15.4 8.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4029) LAT2 PF15703.5 EGR33077.1 - 3.5 7.5 5.8 0.59 10.0 0.4 2.4 2 0 0 2 2 2 0 Linker for activation of T-cells family member 2 Radial_spoke_3 PF06098.11 EGR33079.1 - 6.2e-48 163.5 13.5 8.2e-48 163.1 13.5 1.1 1 0 0 1 1 1 1 Radial spoke protein 3 DDOST_48kD PF03345.14 EGR33079.1 - 0.57 9.0 8.5 0.058 12.2 0.7 2.0 1 1 1 2 2 2 0 Oligosaccharyltransferase 48 kDa subunit beta FAP206 PF12018.8 EGR33080.1 - 2.6e-82 276.4 6.9 2.6e-82 276.4 6.9 2.0 2 0 0 2 2 2 1 Domain of unknown function zf-C2H2 PF00096.26 EGR33081.1 - 0.00016 22.0 0.5 0.00035 20.9 0.5 1.6 1 0 0 1 1 1 1 Zinc finger, C2H2 type ARS2 PF04959.13 EGR33081.1 - 0.00087 19.7 3.9 0.0011 19.4 3.9 1.2 1 0 0 1 1 1 1 Arsenite-resistance protein 2 zf-Di19 PF05605.12 EGR33081.1 - 0.0064 16.8 0.4 0.012 15.9 0.4 1.4 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding FOXP-CC PF16159.5 EGR33081.1 - 0.013 16.1 1.6 0.23 12.1 0.1 2.2 2 0 0 2 2 2 0 FOXP coiled-coil domain zf-C2H2_2 PF12756.7 EGR33081.1 - 0.015 15.6 0.7 0.029 14.7 0.5 1.6 1 1 0 1 1 1 0 C2H2 type zinc-finger (2 copies) zf-C2HC_2 PF13913.6 EGR33081.1 - 0.016 15.1 0.2 0.036 14.0 0.2 1.6 1 0 0 1 1 1 0 zinc-finger of a C2HC-type Ig_Tie2_1 PF10430.9 EGR33081.1 - 0.019 15.3 0.4 0.026 14.9 0.4 1.2 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 FAM183 PF14886.6 EGR33082.1 - 4.6e-31 107.8 6.2 6.2e-31 107.3 6.2 1.2 1 0 0 1 1 1 1 FAM183A and FAM183B related DUF1518 PF07469.12 EGR33082.1 - 0.39 11.1 3.7 0.4 11.1 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1518) ABC_tran PF00005.27 EGR33083.1 - 1.1e-08 35.7 0.5 1.8e-08 35.0 0.1 1.6 2 1 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EGR33083.1 - 7.1e-08 32.2 2.1 3.4e-07 29.9 0.9 1.9 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain FKBP_N_2 PF18023.1 EGR33083.1 - 0.0014 18.7 0.4 0.0023 18.0 0.4 1.4 1 0 0 1 1 1 1 BDBT FKBP like N-terminal AID PF18767.1 EGR33083.1 - 0.0027 17.7 0.1 0.75 9.8 0.0 2.4 2 0 0 2 2 2 2 Activation induced deaminase MCR_beta PF02241.18 EGR33083.1 - 0.064 12.8 0.1 0.071 12.7 0.1 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase beta subunit, C-terminal domain ABC_tran PF00005.27 EGR33084.1 - 5.4e-08 33.4 0.0 1.2e-07 32.3 0.0 1.6 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EGR33084.1 - 0.013 15.0 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Ribosomal_L27e PF01777.18 EGR33085.1 - 8e-31 106.2 5.1 1.3e-30 105.6 5.1 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EGR33085.1 - 0.00053 19.9 0.5 0.0011 18.8 0.5 1.6 1 0 0 1 1 1 1 KOW motif PhoLip_ATPase_C PF16212.5 EGR33087.1 - 1.2e-66 225.1 24.5 1.2e-66 225.1 24.5 2.8 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGR33087.1 - 1.3e-18 66.4 5.1 1.3e-18 66.4 5.1 3.4 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGR33087.1 - 5.5e-15 55.2 0.2 3.9e-13 49.3 0.0 2.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGR33087.1 - 8.8e-14 52.3 0.3 1.2e-07 32.2 0.0 2.7 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGR33087.1 - 2.9e-08 33.4 0.0 1.8e-07 30.9 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGR33087.1 - 0.00017 21.4 5.5 0.00017 21.4 5.5 3.7 3 1 1 4 4 4 1 haloacid dehalogenase-like hydrolase DUF4392 PF14336.6 EGR33087.1 - 0.12 11.8 2.5 2.2 7.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4392) EF-hand_1 PF00036.32 EGR33088.1 - 1.5e-31 105.6 8.9 1.1e-08 34.0 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGR33088.1 - 2.3e-29 101.6 10.4 4.4e-16 59.1 2.3 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR33088.1 - 8.5e-26 87.7 8.9 1.9e-07 30.4 0.1 4.5 4 1 1 5 5 5 4 EF-hand domain EF-hand_8 PF13833.6 EGR33088.1 - 2.4e-22 78.5 9.7 5.6e-12 45.3 0.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.6 EGR33088.1 - 9.6e-14 51.5 1.4 1.3e-05 25.4 0.2 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGR33088.1 - 2.6e-12 45.7 5.7 4.7e-05 22.7 0.6 3.8 3 0 0 3 3 3 3 EF hand EF-hand_4 PF12763.7 EGR33088.1 - 2.6e-06 27.3 4.4 0.033 14.1 0.1 2.7 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 EGR33088.1 - 0.0005 20.9 2.3 0.21 12.5 0.3 2.2 1 1 1 2 2 2 2 EF-hand domain Caleosin PF05042.13 EGR33088.1 - 0.00069 19.6 2.6 8.1 6.3 0.2 3.9 1 1 3 4 4 4 1 Caleosin related protein EF-hand_14 PF17959.1 EGR33088.1 - 0.00082 19.7 3.3 0.32 11.4 0.4 2.6 2 1 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EGR33088.1 - 0.00095 19.5 3.8 0.45 10.8 0.5 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF1722 PF08349.11 EGR33088.1 - 0.011 15.9 3.1 3.9 7.8 0.1 3.0 1 1 1 3 3 3 0 Protein of unknown function (DUF1722) SurA_N_2 PF13623.6 EGR33088.1 - 0.014 15.3 6.7 0.09 12.6 0.5 2.5 1 1 1 2 2 2 0 SurA N-terminal domain DUF1636 PF07845.11 EGR33088.1 - 0.016 15.6 0.0 8.7 6.8 0.0 3.5 1 1 3 4 4 4 0 Protein of unknown function (DUF1636) UBA_2 PF08587.11 EGR33088.1 - 0.025 14.7 1.0 8.4 6.6 0.0 3.1 2 1 0 2 2 2 0 Ubiquitin associated domain (UBA) SRI PF08236.11 EGR33088.1 - 0.028 14.6 0.8 1.3 9.2 0.0 2.6 2 1 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain SUB1_ProdP9 PF18213.1 EGR33088.1 - 0.14 12.0 0.8 0.26 11.2 0.1 1.8 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 MgtE_N PF03448.17 EGR33088.1 - 0.22 12.1 5.6 0.23 12.1 1.1 2.5 1 1 0 2 2 2 0 MgtE intracellular N domain DUF3349 PF11829.8 EGR33088.1 - 0.44 11.4 3.1 23 5.8 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3349) Pkinase PF00069.25 EGR33089.1 - 3.3e-29 102.1 0.7 2.3e-27 96.0 0.3 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33089.1 - 1.7e-11 44.0 0.0 1.8e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Choline_kinase PF01633.20 EGR33089.1 - 5.7e-05 22.8 0.2 8.3e-05 22.3 0.2 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EGR33089.1 - 0.00075 18.9 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGR33089.1 - 0.0038 16.9 0.5 0.012 15.3 0.1 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EGR33089.1 - 0.004 17.1 0.0 0.0058 16.6 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGR33089.1 - 0.023 14.0 0.0 0.026 13.8 0.0 1.1 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 EGR33089.1 - 0.024 13.4 0.1 0.029 13.1 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Proton_antipo_C PF01010.19 EGR33089.1 - 0.049 13.3 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 NADH-dehyrogenase subunit F, TMs, (complex I) C-terminus RhoGAP PF00620.27 EGR33090.1 - 5.7e-19 68.4 1.1 5.7e-19 68.4 1.1 2.1 2 1 0 2 2 2 1 RhoGAP domain CRAL_TRIO_2 PF13716.6 EGR33090.1 - 2e-08 34.5 3.6 2e-08 34.5 3.6 2.3 2 1 1 3 3 3 1 Divergent CRAL/TRIO domain Kinesin PF00225.23 EGR33091.1 - 7.5e-16 58.0 2.2 7.5e-16 58.0 2.2 2.5 2 1 0 2 2 2 1 Kinesin motor domain WD40 PF00400.32 EGR33091.1 - 3.2e-12 46.7 7.4 9.4e-06 26.3 0.2 6.8 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR33091.1 - 0.02 15.2 8.5 5.2 7.4 0.0 6.9 4 1 2 8 8 8 0 Anaphase-promoting complex subunit 4 WD40 domain Aminotran_5 PF00266.19 EGR33093.1 - 3e-57 194.3 0.0 3.9e-45 154.4 0.2 2.0 2 0 0 2 2 2 2 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGR33093.1 - 0.0013 18.1 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family PB1-F2 PF11986.8 EGR33094.1 - 0.0095 16.1 2.9 0.013 15.7 2.9 1.3 1 0 0 1 1 1 1 Influenza A Proapoptotic protein Arm_vescicular PF18770.1 EGR33094.1 - 0.11 12.5 0.4 0.19 11.7 0.2 1.6 1 1 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor IES5 PF17335.2 EGR33095.1 - 0.046 14.0 5.6 0.5 10.6 0.6 2.7 2 0 0 2 2 2 0 Ino80 complex subunit 5 Transglut_core PF01841.19 EGR33096.1 - 0.045 14.2 0.0 0.2 12.2 0.0 2.1 2 0 0 2 2 2 0 Transglutaminase-like superfamily TPR_11 PF13414.6 EGR33096.1 - 0.062 13.0 0.1 1.3 8.7 0.1 2.6 2 0 0 2 2 2 0 TPR repeat Hydrolase_4 PF12146.8 EGR33097.1 - 4.4e-12 45.8 0.0 9e-11 41.5 0.0 2.1 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR33097.1 - 1.3e-09 38.0 0.0 1.8e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EGR33097.1 - 8.9e-05 22.2 0.0 0.00012 21.8 0.0 1.1 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 EGR33097.1 - 0.0031 17.2 0.0 0.0052 16.5 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.7 EGR33097.1 - 0.0072 17.0 0.0 0.0088 16.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Pkinase PF00069.25 EGR33098.1 - 4.4e-72 242.6 0.3 7.1e-72 241.9 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33098.1 - 2.5e-37 128.6 0.0 3.8e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR33098.1 - 2.3e-06 26.7 0.0 4.2e-06 25.8 0.0 1.5 1 1 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGR33098.1 - 0.00011 21.4 5.7 0.00011 21.4 5.7 1.7 2 0 0 2 2 2 1 Haspin like kinase domain DUF4881 PF16222.5 EGR33099.1 - 0.00047 20.1 1.8 0.0013 18.6 0.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4881) DUF3533 PF12051.8 EGR33099.1 - 1.5 7.7 9.3 2.6 6.9 9.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) DUF4407 PF14362.6 EGR33099.1 - 1.6 8.0 14.5 2.4 7.4 14.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ALMT PF11744.8 EGR33099.1 - 1.9 7.2 15.8 2.9 6.6 15.8 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter 2OG-FeII_Oxy_2 PF13532.6 EGR33100.1 - 1.9e-23 83.7 0.1 5.7e-22 78.9 0.1 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PRP38 PF03371.15 EGR33101.1 - 1.1e-53 181.7 0.6 1.5e-53 181.2 0.6 1.2 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 EGR33101.1 - 0.31 11.7 7.1 0.59 10.8 7.1 1.4 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Zip PF02535.22 EGR33101.1 - 0.58 9.3 1.6 0.81 8.8 1.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 EGR33101.1 - 5.8 6.7 12.0 8.4 6.1 12.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRM_1 PF00076.22 EGR33102.1 - 8.8e-23 79.9 4.4 1.5e-10 40.7 0.1 3.8 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EGR33102.1 - 3.1e-20 72.1 3.5 3.1e-20 72.1 3.5 2.6 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_occluded PF16842.5 EGR33102.1 - 3.1e-05 23.7 2.2 0.00035 20.4 0.0 3.7 4 0 0 4 4 4 1 Occluded RNA-recognition motif RRM_5 PF13893.6 EGR33102.1 - 0.0007 19.2 0.1 0.0041 16.7 0.1 2.5 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BDV_P24 PF06595.11 EGR33102.1 - 0.56 10.1 3.5 0.27 11.1 0.4 2.0 2 0 0 2 2 2 0 Borna disease virus P24 protein RRM_3 PF08777.11 EGR33102.1 - 3.3 7.8 22.8 0.57 10.3 0.1 4.4 4 0 0 4 4 4 0 RNA binding motif Ribosomal_S8e PF01201.22 EGR33103.1 - 6.1e-46 156.0 10.1 1.4e-45 154.8 10.1 1.7 1 1 0 1 1 1 1 Ribosomal protein S8e WH1 PF00568.23 EGR33104.1 - 0.24 11.3 3.9 0.13 12.2 0.5 2.3 3 0 0 3 3 3 0 WH1 domain AP2 PF00847.20 EGR33104.1 - 0.47 10.7 0.1 0.47 10.7 0.1 2.4 3 0 0 3 3 3 0 AP2 domain NUMOD4 PF07463.11 EGR33105.1 - 6 7.2 11.0 0.51 10.6 1.5 3.9 3 0 0 3 3 3 0 NUMOD4 motif PX PF00787.24 EGR33107.1 - 7.8e-19 67.7 0.0 7.8e-19 67.7 0.0 4.4 4 1 1 5 5 5 1 PX domain Pkinase PF00069.25 EGR33108.1 - 3e-24 85.8 2.1 4.4e-22 78.7 0.0 2.6 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33108.1 - 1.9e-09 37.2 1.3 3.1e-09 36.5 0.1 1.9 2 1 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 EGR33108.1 - 0.00024 21.1 0.0 0.0004 20.4 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGR33108.1 - 0.011 14.5 0.1 0.02 13.7 0.0 1.6 1 1 1 2 2 2 0 Fungal protein kinase Kdo PF06293.14 EGR33108.1 - 0.091 12.1 1.3 0.17 11.2 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family GerE PF00196.19 EGR33108.1 - 0.14 11.7 2.5 0.54 9.8 1.7 2.1 2 0 0 2 2 2 0 Bacterial regulatory proteins, luxR family Ribosomal_S6 PF01250.17 EGR33109.1 - 1.4e-10 41.3 0.0 2.1e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S6 Spore_YhcN_YlaJ PF09580.10 EGR33109.1 - 0.062 13.4 0.0 0.083 13.0 0.0 1.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) IBN_N PF03810.19 EGR33110.1 - 1.7e-15 56.7 1.1 1.7e-15 56.7 1.1 4.9 5 0 0 5 5 5 1 Importin-beta N-terminal domain DCB PF16213.5 EGR33110.1 - 0.027 14.2 1.0 0.11 12.2 0.1 2.5 2 0 0 2 2 2 0 Dimerisation and cyclophilin-binding domain of Mon2 HEAT_2 PF13646.6 EGR33110.1 - 0.052 13.9 0.0 0.45 10.9 0.0 2.6 2 1 0 2 2 2 0 HEAT repeats TetR_C_4 PF08359.11 EGR33110.1 - 0.1 12.8 0.2 0.1 12.8 0.2 3.3 3 0 0 3 3 3 0 YsiA-like protein, C-terminal region ParcG PF10274.9 EGR33110.1 - 0.29 11.2 6.4 0.41 10.8 0.1 3.9 4 0 0 4 4 4 0 Parkin co-regulated protein Mis12 PF05859.12 EGR33110.1 - 6.5 6.8 12.0 1.2 9.2 6.0 3.0 3 1 0 3 3 3 0 Mis12 protein OST_IS PF18246.1 EGR33111.1 - 3.4 8.0 5.9 0.72 10.2 0.1 2.9 3 0 0 3 3 3 0 Oligosaccharyltransferase Insert domain DUF3116 PF11313.8 EGR33112.1 - 0.029 14.2 2.4 0.072 13.0 1.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3116) Apolipoprotein PF01442.18 EGR33112.1 - 0.043 13.7 5.2 0.32 10.8 5.1 2.0 1 1 0 1 1 1 0 Apolipoprotein A1/A4/E domain DUF3410 PF11890.8 EGR33112.1 - 0.055 13.3 0.1 0.22 11.4 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3410) DUF3095 PF11294.8 EGR33112.1 - 0.089 11.8 1.0 0.18 10.8 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3095) Baculo_PEP_C PF04513.12 EGR33112.1 - 1.2 9.2 16.8 1 9.4 5.3 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Uso1_p115_C PF04871.13 EGR33112.1 - 1.5 9.2 11.1 0.33 11.3 5.2 2.2 2 0 0 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region FANCI_S2 PF14676.6 EGR33112.1 - 1.6 9.0 8.1 14 6.0 4.5 2.8 2 1 0 2 2 2 0 FANCI solenoid 2 SseC PF04888.12 EGR33112.1 - 1.7 8.1 14.8 2.4 7.7 1.9 2.4 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family DUF87 PF01935.17 EGR33112.1 - 7.8 6.5 12.7 3.7 7.6 8.2 2.5 1 1 1 2 2 2 0 Helicase HerA, central domain NCKAP5 PF15246.6 EGR33112.1 - 8.5 5.9 13.9 14 5.1 13.7 1.4 1 1 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein Peptidase_S49 PF01343.18 EGR33113.1 - 0.0017 18.4 0.0 0.003 17.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase family S49 BTV_NS2 PF04514.12 EGR33113.1 - 0.13 11.1 0.1 0.15 10.8 0.1 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 PRP38 PF03371.15 EGR33114.1 - 8.7e-46 155.9 0.0 3.1e-45 154.1 0.0 2.0 1 0 0 1 1 1 1 PRP38 family Med31 PF05669.12 EGR33114.1 - 0.23 11.5 6.0 1.4 8.9 6.0 2.4 1 0 0 1 1 1 0 SOH1 PDEase_I PF00233.19 EGR33117.1 - 1.9e-65 220.9 11.1 1.9e-65 220.9 11.1 1.6 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 EGR33117.1 - 0.058 13.6 0.9 0.29 11.4 0.9 2.1 1 1 0 1 1 1 0 HD domain Cyclin PF08613.11 EGR33118.1 - 1.4e-35 123.1 2.0 1.5e-35 122.9 2.0 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EGR33118.1 - 1.9e-12 47.1 2.6 3e-12 46.4 0.4 1.9 1 1 0 2 2 2 1 Cyclin, N-terminal domain 2-Hacid_dh_C PF02826.19 EGR33120.1 - 2.4e-53 180.2 0.0 3.5e-53 179.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGR33120.1 - 1.7e-27 95.7 0.1 2.1e-27 95.4 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGR33120.1 - 0.0003 21.0 0.0 0.00059 20.0 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EGR33120.1 - 0.0019 17.8 0.1 0.0057 16.3 0.0 1.8 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 EGR33120.1 - 0.021 15.4 0.0 0.057 14.0 0.0 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EGR33120.1 - 0.029 14.4 0.0 0.069 13.2 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PrpR_N PF06506.11 EGR33120.1 - 0.033 13.8 0.3 0.15 11.6 0.0 2.2 3 0 0 3 3 3 0 Propionate catabolism activator AlaDh_PNT_C PF01262.21 EGR33120.1 - 0.039 13.2 0.0 0.1 11.9 0.0 1.7 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EGR33120.1 - 0.075 12.9 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Septin PF00735.18 EGR33121.1 - 1.6e-48 165.4 8.4 3.6e-48 164.3 8.4 1.5 1 1 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EGR33121.1 - 3.9e-08 33.4 0.4 7.7e-08 32.4 0.4 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGR33121.1 - 1.8e-06 27.4 0.9 1e-05 25.0 0.6 2.2 1 1 1 2 2 2 1 AIG1 family Ras PF00071.22 EGR33121.1 - 0.00089 18.9 1.3 0.002 17.8 1.3 1.6 1 0 0 1 1 1 1 Ras family AAA_22 PF13401.6 EGR33121.1 - 0.0016 18.7 0.0 0.0039 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 EGR33121.1 - 0.0021 17.6 1.1 0.13 11.7 0.2 3.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Roc PF08477.13 EGR33121.1 - 0.0024 18.1 4.2 0.0067 16.6 3.4 2.2 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EGR33121.1 - 0.0061 16.5 0.5 0.022 14.7 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EGR33121.1 - 0.01 15.3 0.2 0.022 14.2 0.2 1.5 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 EGR33121.1 - 0.013 16.0 1.1 0.028 14.9 0.9 1.6 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EGR33121.1 - 0.048 13.4 0.0 0.11 12.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 EGR33121.1 - 0.086 12.9 9.7 0.86 9.6 1.2 3.3 1 1 2 3 3 3 0 Dynamin family AAA_33 PF13671.6 EGR33121.1 - 0.095 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGR33121.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Hydrolase_4 PF12146.8 EGR33123.1 - 4.1e-53 180.1 0.0 4.9e-53 179.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR33123.1 - 2e-13 50.6 0.1 3.1e-13 50.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EGR33123.1 - 8e-06 25.6 0.1 5.3e-05 22.9 0.0 2.0 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EGR33123.1 - 2.5e-05 23.8 0.1 0.0001 21.8 0.0 2.0 2 1 1 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EGR33123.1 - 3.8e-05 24.4 0.0 4.4e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.20 EGR33123.1 - 0.0049 16.5 0.0 0.0097 15.6 0.0 1.5 2 0 0 2 2 2 1 Putative esterase PAF-AH_p_II PF03403.13 EGR33123.1 - 0.01 14.4 0.2 0.092 11.2 0.0 2.0 2 0 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_5 PF12695.7 EGR33123.1 - 0.088 12.6 0.1 0.37 10.6 0.0 2.0 3 0 0 3 3 3 0 Alpha/beta hydrolase family Acyl_transf_2 PF02273.15 EGR33123.1 - 0.11 11.7 0.8 0.16 11.2 0.1 1.5 2 0 0 2 2 2 0 Acyl transferase DUF4505 PF14956.6 EGR33124.1 - 0.0028 17.4 1.3 0.0061 16.3 1.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4505) Pkinase PF00069.25 EGR33125.1 - 1.3e-38 132.9 0.7 1.3e-38 132.9 0.7 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33125.1 - 1.7e-26 93.1 0.4 2.8e-26 92.4 0.4 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_M14 PF00246.24 EGR33125.1 - 1.5e-18 67.6 0.0 2.8e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Zinc carboxypeptidase AstE_AspA PF04952.14 EGR33125.1 - 0.00027 20.1 0.0 0.00042 19.5 0.0 1.2 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family Pkinase_fungal PF17667.1 EGR33125.1 - 0.00034 19.5 0.1 0.0011 17.8 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGR33125.1 - 0.002 17.5 0.0 0.0054 16.1 0.0 1.7 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGR33125.1 - 0.088 12.7 0.0 0.15 11.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family COX14 PF14880.6 EGR33125.1 - 2.9 7.8 4.3 1.4 8.9 0.5 2.4 2 0 0 2 2 2 0 Cytochrome oxidase c assembly GPI2 PF06432.11 EGR33127.1 - 1.7e-06 27.7 3.8 1.7e-05 24.4 3.7 2.0 1 1 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase DUF4200 PF13863.6 EGR33128.1 - 3.8e-19 69.3 29.4 3.8e-19 69.3 29.4 6.2 3 1 4 7 7 7 1 Domain of unknown function (DUF4200) Citrate_synt PF00285.21 EGR33129.1 - 2.5e-107 359.1 0.0 2.8e-107 358.9 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain zf-C2HC5 PF06221.13 EGR33130.1 - 3e-13 49.5 8.2 7.2e-13 48.3 8.2 1.7 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type ASCH PF04266.14 EGR33130.1 - 6.6e-12 46.0 0.0 2.3e-11 44.2 0.0 1.9 1 0 0 1 1 1 1 ASCH domain Cytochrom_C PF00034.21 EGR33130.1 - 0.083 14.0 0.5 0.29 12.3 0.1 2.1 2 0 0 2 2 2 0 Cytochrome c Metallophos PF00149.28 EGR33131.1 - 2.1e-39 136.1 0.1 2.7e-39 135.8 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGR33131.1 - 4.6e-20 71.8 2.2 9.8e-20 70.7 2.2 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain SPK PF04435.18 EGR33132.1 - 0.1 13.0 7.3 0.04 14.3 2.2 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF545) EF1G PF00647.19 EGR33132.1 - 0.14 12.2 2.3 0.11 12.6 0.7 1.7 2 0 0 2 2 2 0 Elongation factor 1 gamma, conserved domain UQ_con PF00179.26 EGR33133.1 - 1.7e-34 118.5 1.4 2e-34 118.2 1.4 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme cNMP_binding PF00027.29 EGR33134.1 - 0.048 13.7 0.0 0.057 13.5 0.0 1.2 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Pro_isomerase PF00160.21 EGR33135.1 - 6.1e-44 150.1 0.3 6.1e-44 150.1 0.3 2.3 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD U-box PF04564.15 EGR33135.1 - 2.4e-06 27.6 0.1 1.4e-05 25.1 0.0 2.4 1 1 1 2 2 2 1 U-box domain zf-NOSIP PF15906.5 EGR33135.1 - 8.1e-05 22.7 0.1 0.00029 20.9 0.1 1.9 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein DUF3215 PF11503.8 EGR33135.1 - 0.085 12.7 0.1 0.19 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3215) Cullin PF00888.22 EGR33136.1 - 9.5e-115 384.5 53.3 9.5e-115 384.5 53.3 2.1 2 0 0 2 2 2 1 Cullin family NAD_binding_4 PF07993.12 EGR33136.1 - 1.1e-63 214.9 0.0 1.9e-63 214.0 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Cullin_Nedd8 PF10557.9 EGR33136.1 - 6.2e-17 61.4 2.0 6.2e-17 61.4 2.0 2.9 2 0 0 2 2 2 1 Cullin protein neddylation domain Sterile PF03015.19 EGR33136.1 - 6.1e-15 55.2 3.0 6.1e-15 55.2 3.0 3.6 4 0 0 4 4 4 1 Male sterility protein Epimerase PF01370.21 EGR33136.1 - 1e-08 34.9 0.0 2.7e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGR33136.1 - 0.0003 20.3 0.7 0.0015 18.0 0.7 2.2 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase LNS2 PF08235.13 EGR33137.1 - 1e-79 267.2 0.6 1.3e-79 266.8 0.6 1.1 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EGR33137.1 - 7.6e-20 70.8 0.3 2e-19 69.4 0.1 1.8 2 0 0 2 2 2 1 lipin, N-terminal conserved region Acid_phosphat_B PF03767.14 EGR33137.1 - 0.0005 19.7 0.2 0.00098 18.8 0.0 1.5 2 0 0 2 2 2 1 HAD superfamily, subfamily IIIB (Acid phosphatase) NIF PF03031.18 EGR33138.1 - 3.5e-30 104.8 0.3 5.9e-30 104.1 0.3 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase WASH-7_mid PF14744.6 EGR33139.1 - 1.4e-77 261.2 7.0 1.7e-77 260.9 7.0 1.0 1 0 0 1 1 1 1 WASH complex subunit 7 WASH-7_N PF14745.6 EGR33140.1 - 6.4e-19 67.9 1.8 5.6e-10 38.3 0.5 2.0 1 1 1 2 2 2 2 WASH complex subunit 7, N-terminal Pkinase PF00069.25 EGR33141.1 - 3.4e-70 236.4 0.1 3.4e-70 236.4 0.1 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33141.1 - 4.2e-46 157.3 0.0 9.8e-46 156.1 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33141.1 - 2.2e-05 23.9 8.7 0.031 13.6 0.1 3.5 3 0 0 3 3 3 2 Kinase-like Glyco_hydro_31 PF01055.26 EGR33142.1 - 8.2e-123 410.8 10.0 1.2e-122 410.3 10.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EGR33142.1 - 5.5e-12 45.9 3.5 7e-10 39.1 1.4 2.9 2 0 0 2 2 2 2 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase PAS_9 PF13426.7 EGR33143.1 - 0.00029 21.1 0.1 0.00029 21.1 0.1 5.1 5 0 0 5 5 5 1 PAS domain PAS PF00989.25 EGR33143.1 - 0.0044 17.0 0.3 0.13 12.3 0.0 3.3 2 1 1 3 3 3 1 PAS fold YjbH PF06082.11 EGR33143.1 - 0.071 11.9 5.6 3.2 6.5 0.0 2.4 2 0 0 2 2 2 0 Exopolysaccharide biosynthesis protein YbjH DUF2407_C PF13373.6 EGR33143.1 - 0.11 12.7 1.5 0.54 10.4 0.6 2.7 2 0 0 2 2 2 0 DUF2407 C-terminal domain Renin_r PF07850.14 EGR33143.1 - 1.3 9.7 18.5 0.075 13.6 0.4 5.1 4 0 0 4 4 4 0 Renin receptor-like protein PBP1_TM PF14812.6 EGR33143.1 - 6.5 7.2 15.1 0.34 11.3 5.5 3.7 4 0 0 4 4 4 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Cytadhesin_P30 PF07271.11 EGR33143.1 - 6.5 6.2 6.4 3.4 7.2 0.1 2.9 3 0 0 3 3 3 0 Cytadhesin P30/P32 RL10P_insert PF17777.1 EGR33144.1 - 1.8e-18 66.3 0.1 3.8e-18 65.3 0.1 1.5 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Radial_spoke PF04712.12 EGR33145.1 - 1.8e-71 241.6 9.9 1e-58 199.6 6.5 2.0 1 1 1 2 2 2 2 Radial spokehead-like protein FlaG PF03646.15 EGR33145.1 - 0.0019 18.3 3.3 0.0052 16.9 3.3 1.7 1 0 0 1 1 1 1 FlaG protein PP2C_C PF07830.13 EGR33145.1 - 0.38 11.2 2.6 0.89 10.1 2.6 1.5 1 0 0 1 1 1 0 Protein serine/threonine phosphatase 2C, C-terminal domain DUF3484 PF11983.8 EGR33145.1 - 2.7 9.2 9.8 5.8 8.1 0.1 2.5 2 0 0 2 2 2 0 Membrane-attachment and polymerisation-promoting switch Prefoldin_2 PF01920.20 EGR33146.1 - 6.8e-12 45.3 8.5 7.5e-12 45.1 8.5 1.0 1 0 0 1 1 1 1 Prefoldin subunit PEX-2N PF09263.10 EGR33146.1 - 0.035 14.4 0.1 0.048 14.0 0.1 1.4 1 0 0 1 1 1 0 Peroxisome biogenesis factor 1, N-terminal Pkinase PF00069.25 EGR33147.1 - 8.7e-64 215.4 0.5 8.7e-64 215.4 0.5 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33147.1 - 3.6e-40 137.9 0.1 3.6e-40 137.9 0.1 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase TFIIA PF03153.13 EGR33147.1 - 0.053 13.5 20.1 0.093 12.7 20.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAM_Exu PF18609.1 EGR33147.1 - 0.099 12.7 0.5 0.58 10.3 0.5 2.5 1 1 0 1 1 1 0 Exuperantia SAM-like domain Renin_r PF07850.14 EGR33147.1 - 3 8.5 6.1 1.4 9.6 3.2 1.9 2 0 0 2 2 2 0 Renin receptor-like protein DUF2722 PF10846.8 EGR33147.1 - 5.7 5.8 23.7 8.4 5.2 23.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) ESCRT-II PF05871.12 EGR33148.1 - 4.8 7.4 12.6 2.2 8.5 9.0 2.0 1 1 1 2 2 2 0 ESCRT-II complex subunit Furin-like_2 PF15913.5 EGR33149.1 - 1e-05 25.6 23.9 1e-05 25.6 23.9 7.7 2 1 3 6 6 6 3 Furin-like repeat, cysteine-rich TPR_1 PF00515.28 EGR33151.1 - 7.6e-13 47.7 8.7 2.3e-07 30.3 0.2 5.0 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGR33151.1 - 6.5e-12 44.6 8.1 7.8e-06 25.6 0.1 5.0 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGR33151.1 - 2.7e-09 36.5 9.4 0.017 15.3 0.0 5.8 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGR33151.1 - 8.7e-09 35.6 1.8 0.00068 19.9 0.2 3.4 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGR33151.1 - 5.6e-08 32.3 0.1 0.00028 20.7 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGR33151.1 - 4.1e-07 30.4 3.4 0.00032 21.2 0.1 3.8 2 2 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR33151.1 - 0.00011 22.4 1.4 0.03 14.5 0.1 2.7 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EGR33151.1 - 0.00019 22.0 0.0 0.014 16.1 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGR33151.1 - 0.00031 21.2 7.7 0.033 14.8 0.1 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGR33151.1 - 0.00094 19.8 0.0 23 6.2 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGR33151.1 - 0.0022 17.8 1.1 0.25 11.3 0.0 3.3 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGR33151.1 - 0.017 14.8 10.0 0.33 10.7 0.4 4.7 3 1 1 4 4 4 0 TPR repeat TPR_17 PF13431.6 EGR33151.1 - 0.032 14.6 1.3 20 5.8 0.0 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat PPR_3 PF13812.6 EGR33151.1 - 0.047 13.8 0.0 0.047 13.8 0.0 2.3 3 0 0 3 3 2 0 Pentatricopeptide repeat domain PPR PF01535.20 EGR33151.1 - 0.072 13.4 0.0 0.35 11.2 0.0 2.1 1 0 0 1 1 1 0 PPR repeat Pkinase PF00069.25 EGR33152.1 - 4e-76 255.9 0.1 7.8e-76 254.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33152.1 - 5.2e-35 121.0 0.0 3.3e-34 118.3 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase PSDC PF12588.8 EGR33152.1 - 0.009 16.0 1.1 3.5 7.6 0.1 2.7 2 0 0 2 2 2 2 Phophatidylserine decarboxylase DUF1189 PF06691.11 EGR33152.1 - 0.13 11.8 2.7 0.2 11.2 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1189) Fanconi_A_N PF15865.5 EGR33152.1 - 0.21 10.9 1.5 1.4 8.3 0.1 2.0 2 0 0 2 2 2 0 Fanconi anaemia group A protein N terminus VSP PF03302.13 EGR33154.1 - 8.9e-08 31.4 89.2 0.0035 16.2 20.0 4.9 2 1 1 4 4 4 3 Giardia variant-specific surface protein Pkinase PF00069.25 EGR33155.1 - 2.7e-61 207.3 2.2 2.7e-61 207.3 2.2 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33155.1 - 3.5e-32 111.7 0.9 9.8e-32 110.2 0.9 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33155.1 - 1.3e-07 31.3 0.1 1.3e-07 31.3 0.1 2.1 2 1 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EGR33155.1 - 8.5e-05 22.2 3.0 8.5e-05 22.2 3.0 1.9 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EGR33155.1 - 0.043 13.7 0.0 0.062 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family FlaG PF03646.15 EGR33155.1 - 0.055 13.6 7.7 1.9 8.7 0.0 2.6 2 0 0 2 2 2 0 FlaG protein Thr_dehydrat_C PF00585.18 EGR33156.1 - 0.051 13.3 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 C-terminal regulatory domain of Threonine dehydratase Nab2 PF11517.8 EGR33156.1 - 0.078 13.3 0.5 2.3 8.6 0.1 2.6 2 0 0 2 2 2 0 Nuclear abundant poly(A) RNA-bind protein 2 (Nab2) Arf PF00025.21 EGR33158.1 - 1.2e-45 155.1 0.8 1.7e-45 154.6 0.8 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGR33158.1 - 2.7e-12 47.0 0.2 7.7e-12 45.5 0.1 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EGR33158.1 - 7.9e-11 41.8 0.3 1.4e-10 40.9 0.3 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EGR33158.1 - 4.8e-09 35.8 10.7 7.9e-07 28.5 10.4 3.0 1 1 0 1 1 1 1 G-protein alpha subunit SRPRB PF09439.10 EGR33158.1 - 2.4e-08 33.6 0.0 5e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGR33158.1 - 2.7e-07 30.7 0.0 5.3e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 EGR33158.1 - 4.9e-06 26.2 0.1 1.2e-05 24.9 0.1 1.6 1 1 0 1 1 1 1 Ras family Swi3 PF07962.12 EGR33158.1 - 0.026 14.5 0.6 1.2 9.2 0.1 3.3 4 0 0 4 4 4 0 Replication Fork Protection Component Swi3 AAA_18 PF13238.6 EGR33158.1 - 0.038 14.5 1.4 0.055 14.0 0.1 2.0 2 2 0 2 2 2 0 AAA domain PDEase_I PF00233.19 EGR33159.1 - 2.2e-47 161.8 30.7 2.1e-46 158.6 16.7 3.3 3 1 0 3 3 3 2 3'5'-cyclic nucleotide phosphodiesterase Nucleoporin_FG2 PF15967.5 EGR33159.1 - 0.23 9.9 4.2 0.32 9.5 4.2 1.1 1 0 0 1 1 1 0 Nucleoporin FG repeated region Pkinase PF00069.25 EGR33161.1 - 1.2e-80 270.7 2.3 2e-80 270.0 0.0 2.5 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33161.1 - 3.1e-49 167.6 0.3 1.3e-48 165.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase HEAT PF02985.22 EGR33161.1 - 3.8e-13 48.5 0.0 0.00029 20.8 0.0 5.3 4 0 0 4 4 4 3 HEAT repeat HEAT_EZ PF13513.6 EGR33161.1 - 7.5e-09 35.9 0.0 3.8e-07 30.5 0.0 3.0 2 0 0 2 2 2 1 HEAT-like repeat HEAT_2 PF13646.6 EGR33161.1 - 4e-08 33.5 0.0 1.4e-05 25.3 0.0 3.5 3 0 0 3 3 3 1 HEAT repeats Arm PF00514.23 EGR33161.1 - 1.7e-06 27.8 0.0 0.00011 22.2 0.0 3.9 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Kinase-like PF14531.6 EGR33161.1 - 2.5e-06 27.0 7.0 8e-05 22.1 0.0 4.2 4 1 0 4 4 4 1 Kinase-like Pkinase_fungal PF17667.1 EGR33161.1 - 0.00024 20.0 0.0 0.00054 18.9 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EGR33161.1 - 0.00086 18.9 0.1 0.005 16.4 0.0 2.2 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 EGR33161.1 - 0.0077 16.2 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGR33161.1 - 0.035 13.7 0.5 0.47 10.0 0.0 2.8 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Vac14_Fab1_bd PF12755.7 EGR33161.1 - 0.074 13.7 3.6 1.3 9.7 0.0 4.5 4 1 1 5 5 4 0 Vacuolar 14 Fab1-binding region Kdo PF06293.14 EGR33161.1 - 0.075 12.4 0.0 0.25 10.7 0.0 1.9 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Vps39_1 PF10366.9 EGR33161.1 - 0.49 10.7 5.0 5.2 7.4 0.1 4.6 4 0 0 4 4 4 0 Vacuolar sorting protein 39 domain 1 HARP PF07443.13 EGR33161.1 - 9.3 6.0 6.3 6 6.6 0.1 3.5 4 0 0 4 4 4 0 HepA-related protein (HARP) GCIP PF13324.6 EGR33162.1 - 0.0019 17.9 2.0 0.0019 17.8 2.0 1.2 1 0 0 1 1 1 1 Grap2 and cyclin-D-interacting Chordopox_E11 PF06138.12 EGR33162.1 - 0.021 15.1 0.1 0.033 14.5 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus E11 protein Pkinase PF00069.25 EGR33163.1 - 1.5e-05 24.5 0.1 2.4e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain RlaP PF10127.9 EGR33163.1 - 0.035 13.7 1.6 0.058 13.0 1.5 1.5 1 1 0 1 1 1 0 RNA repair pathway DNA polymerase beta family LCM PF04072.14 EGR33163.1 - 0.069 13.1 0.1 0.096 12.6 0.1 1.2 1 0 0 1 1 1 0 Leucine carboxyl methyltransferase Ribosomal_L29e PF01779.17 EGR33164.1 - 5.7e-19 68.2 10.3 5.7e-19 68.2 10.3 1.8 2 0 0 2 2 2 1 Ribosomal L29e protein family Peptidase_M54 PF07998.11 EGR33165.1 - 1.1e-06 28.7 1.2 1.6e-06 28.3 1.2 1.3 1 0 0 1 1 1 1 Peptidase family M54 Peptidase_M10 PF00413.24 EGR33165.1 - 0.0094 15.8 0.1 0.013 15.4 0.1 1.3 1 0 0 1 1 1 1 Matrixin Reprolysin_4 PF13583.6 EGR33165.1 - 0.066 12.9 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 EGR33165.1 - 0.094 12.3 0.9 0.19 11.3 0.6 1.6 2 0 0 2 2 2 0 Dual-action HEIGH metallo-peptidase PP2C PF00481.21 EGR33166.1 - 1.9e-66 224.4 0.1 4.5e-65 219.8 0.1 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C SHIPPO-rpt PF07004.12 EGR33167.1 - 4.1e-06 27.5 35.4 0.0045 17.8 0.3 6.5 7 1 0 7 7 7 4 Sperm-tail PG-rich repeat YtkA PF13115.6 EGR33167.1 - 0.004 17.7 0.5 5.4 7.7 0.0 3.9 3 2 1 4 4 4 1 YtkA-like Ank_5 PF13857.6 EGR33168.1 - 1e-08 35.2 0.0 6.1e-06 26.4 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGR33168.1 - 1.9e-08 34.7 0.3 1.7e-07 31.6 0.0 2.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGR33168.1 - 2.2e-08 34.5 0.0 6.6e-08 33.0 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGR33168.1 - 9.7e-07 28.6 0.0 0.021 15.3 0.0 3.5 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EGR33168.1 - 0.0002 21.7 0.1 0.022 15.2 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat SprT-like PF10263.9 EGR33168.1 - 0.95 9.3 5.9 0.64 9.9 0.9 3.0 2 1 0 2 2 2 0 SprT-like family WD40 PF00400.32 EGR33171.1 - 7.8e-22 77.2 3.6 1.8e-07 31.7 0.2 5.8 5 0 0 5 5 5 4 WD domain, G-beta repeat MFS_1 PF07690.16 EGR33171.1 - 5.9e-15 55.0 10.5 8.7e-15 54.5 10.5 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.6 EGR33171.1 - 1.5e-06 27.1 10.2 1.8e-06 26.8 9.3 1.5 1 1 1 2 2 2 1 MFS/sugar transport protein ANAPC4_WD40 PF12894.7 EGR33171.1 - 3e-06 27.4 0.2 0.012 15.9 0.0 4.1 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain DUF4038 PF13204.6 EGR33171.1 - 0.048 13.3 2.8 0.095 12.3 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4038) Katanin_con80 PF13925.6 EGR33172.1 - 0.00066 19.8 2.4 0.0043 17.1 2.0 2.1 1 1 0 1 1 1 1 con80 domain of Katanin dsDNA_bind PF01984.20 EGR33172.1 - 0.015 15.6 0.3 1.3 9.3 0.0 2.3 1 1 1 2 2 2 0 Double-stranded DNA-binding domain Clathrin PF00637.20 EGR33173.1 - 1.3e-129 427.1 46.5 3.8e-34 117.6 7.1 7.2 7 0 0 7 7 7 6 Region in Clathrin and VPS Clathrin_H_link PF13838.6 EGR33173.1 - 4.8e-21 74.4 0.6 4.3e-20 71.4 0.1 2.9 2 0 0 2 2 2 1 Clathrin-H-link Coatomer_WDAD PF04053.14 EGR33173.1 - 2.7e-07 30.0 18.1 0.00015 20.9 0.5 5.2 5 1 0 5 5 5 2 Coatomer WD associated region TPR_1 PF00515.28 EGR33173.1 - 9.6e-05 22.0 11.3 0.0075 16.1 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGR33173.1 - 0.00026 21.0 5.5 1.7 9.1 0.3 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat Clathrin_propel PF01394.20 EGR33173.1 - 0.0045 17.2 1.7 5.4 7.5 0.1 3.9 4 0 0 4 4 4 2 Clathrin propeller repeat Mic1 PF07035.12 EGR33173.1 - 0.039 13.7 8.7 1.2 8.9 0.3 4.8 4 1 0 4 4 4 0 Colon cancer-associated protein Mic1-like TPR_2 PF07719.17 EGR33173.1 - 0.058 13.5 11.8 0.37 11.0 0.0 5.5 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGR33173.1 - 0.078 13.8 0.0 52 5.1 0.0 5.3 6 0 0 6 6 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGR33173.1 - 0.14 12.5 2.0 28 5.1 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR33173.1 - 0.17 12.1 4.1 0.58 10.4 0.2 3.9 4 1 0 4 4 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Atx10homo_assoc PF09759.9 EGR33173.1 - 3.1 7.9 7.0 1.4 9.0 0.2 3.5 3 1 0 3 3 3 0 Spinocerebellar ataxia type 10 protein domain BT1 PF03092.16 EGR33174.1 - 1.2e-42 145.9 6.8 1.5e-42 145.5 6.8 1.0 1 0 0 1 1 1 1 BT1 family MFS_1 PF07690.16 EGR33174.1 - 3.3e-07 29.5 0.1 5e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF456 PF04306.13 EGR33174.1 - 0.69 10.2 7.6 0.14 12.4 0.9 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF456) CAP PF00188.26 EGR33175.1 - 2e-25 90.0 0.0 5.3e-11 43.4 0.0 4.4 2 2 3 5 5 5 2 Cysteine-rich secretory protein family TFIIA PF03153.13 EGR33175.1 - 0.33 10.9 45.2 0.26 11.2 27.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Miga PF10265.9 EGR33175.1 - 2.6 6.9 9.6 0.43 9.5 3.3 2.0 2 0 0 2 2 2 0 Mitoguardin adh_short PF00106.25 EGR33176.1 - 5.7e-29 101.0 0.5 4.7e-24 84.9 0.3 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGR33176.1 - 7.3e-22 78.1 0.0 4.7e-18 65.6 0.0 2.1 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGR33176.1 - 7.3e-09 35.8 0.0 9.9e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EGR33176.1 - 4.8e-05 23.6 0.0 0.026 14.8 0.0 2.1 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain Fe_hyd_lg_C PF02906.14 EGR33176.1 - 0.13 12.0 0.1 0.27 10.9 0.1 1.6 1 0 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain DUF4586 PF15239.6 EGR33176.1 - 0.29 11.3 2.0 7.3 6.7 0.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4586) Porin_3 PF01459.22 EGR33178.1 - 0.002 17.6 5.2 0.013 15.0 5.0 2.3 1 1 0 1 1 1 1 Eukaryotic porin Abhydrolase_2 PF02230.16 EGR33179.1 - 1.6e-40 139.3 1.3 1.9e-40 139.0 1.3 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 EGR33179.1 - 1.2e-10 41.3 0.0 1.7e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family Esterase PF00756.20 EGR33179.1 - 7.7e-08 32.3 0.1 8.7e-07 28.8 0.1 1.9 1 1 0 1 1 1 1 Putative esterase FSH1 PF03959.13 EGR33179.1 - 2.5e-06 27.3 0.3 6.4e-06 26.0 0.3 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 EGR33179.1 - 2.2e-05 23.8 0.3 0.45 9.8 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGR33179.1 - 7.9e-05 22.2 0.3 0.0014 18.1 0.0 2.2 1 1 1 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 EGR33179.1 - 0.0002 21.2 0.0 0.00035 20.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGR33179.1 - 0.0037 17.0 0.6 2.9 7.4 0.1 3.1 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 EGR33179.1 - 0.0099 15.8 0.0 1.2 8.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold WD40 PF00400.32 EGR33180.1 - 6e-15 55.4 5.3 4.7e-05 24.1 0.2 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR33180.1 - 1e-05 25.8 0.4 0.41 11.0 0.0 3.5 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_N PF14781.6 EGR33180.1 - 0.061 13.2 0.1 0.3 11.0 0.2 2.1 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal DUF4506 PF14958.6 EGR33180.1 - 0.11 12.0 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4506) EF-hand_1 PF00036.32 EGR33181.1 - 1e-14 52.9 8.6 1e-06 27.8 0.3 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGR33181.1 - 1.8e-12 47.5 3.3 3.7e-12 46.5 3.3 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGR33181.1 - 4.4e-12 44.9 5.5 2.9e-07 29.9 0.3 3.0 3 0 0 3 3 3 2 EF-hand domain RabGAP-TBC PF00566.18 EGR33181.1 - 3.8e-10 39.8 5.4 7.3e-10 38.9 5.4 1.5 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EF-hand_5 PF13202.6 EGR33181.1 - 3e-09 35.9 8.1 0.00013 21.3 0.5 2.5 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 EGR33181.1 - 2.7e-06 27.6 0.1 1.1e-05 25.7 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 EGR33181.1 - 3.8e-05 23.5 3.4 0.098 12.5 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_4 PF12763.7 EGR33181.1 - 0.00022 21.1 1.2 0.00022 21.1 1.2 2.2 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand DUF1398 PF07166.11 EGR33181.1 - 0.091 12.8 0.1 0.16 12.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1398) MFS_1 PF07690.16 EGR33182.1 - 9.4e-06 24.8 0.1 1.8e-05 23.8 0.1 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Ax_dynein_light PF10211.9 EGR33183.1 - 8.6e-58 195.4 2.4 1.5e-57 194.6 2.4 1.3 1 0 0 1 1 1 1 Axonemal dynein light chain Brix PF04427.18 EGR33184.1 - 2.3e-35 122.5 1.5 2.7e-34 119.0 1.5 2.2 1 1 0 1 1 1 1 Brix domain DnaJ_C PF01556.18 EGR33185.1 - 7.4e-32 110.5 3.9 1.3e-31 109.7 3.9 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGR33185.1 - 3.5e-17 62.3 1.9 8.6e-17 61.0 1.9 1.7 1 0 0 1 1 1 1 DnaJ domain tRNA-Thr_ED PF08915.11 EGR33185.1 - 0.033 14.2 0.0 0.09 12.8 0.0 1.9 1 1 0 1 1 1 0 Archaea-specific editing domain of threonyl-tRNA synthetase LRR_6 PF13516.6 EGR33186.1 - 1.5e-20 71.4 38.0 0.00036 20.3 0.1 9.2 10 0 0 10 10 10 6 Leucine Rich repeat LRR_4 PF12799.7 EGR33186.1 - 1.8e-07 31.4 33.0 0.0093 16.4 2.7 6.5 5 2 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGR33186.1 - 0.00014 21.5 37.5 0.046 13.5 2.8 8.0 3 3 3 6 6 6 4 Leucine rich repeat LRR_1 PF00560.33 EGR33186.1 - 0.0013 18.9 19.4 34 5.5 0.1 8.0 7 2 0 7 7 7 0 Leucine Rich Repeat HNOB PF07700.15 EGR33186.1 - 0.045 13.7 0.1 8.9 6.2 0.0 2.4 2 0 0 2 2 2 0 Haem-NO-binding LRR_2 PF07723.13 EGR33186.1 - 0.59 10.9 2.3 3.2 8.6 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich Repeat Fez1 PF06818.15 EGR33187.1 - 9.8e-06 26.2 91.2 0.016 15.6 12.0 4.9 1 1 3 4 4 4 3 Fez1 HMMR_N PF15905.5 EGR33187.1 - 4.8e-05 23.0 25.5 4.8e-05 23.0 25.5 5.1 1 1 2 4 4 4 2 Hyaluronan mediated motility receptor N-terminal Atg14 PF10186.9 EGR33187.1 - 0.0039 16.3 18.2 0.0039 16.3 18.2 5.9 1 1 5 6 6 4 3 Vacuolar sorting 38 and autophagy-related subunit 14 CENP-F_leu_zip PF10473.9 EGR33187.1 - 0.0057 16.7 12.9 0.0057 16.7 12.9 7.2 1 1 6 7 7 5 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TRAF_BIRC3_bd PF16673.5 EGR33187.1 - 0.0083 15.9 8.0 0.0083 15.9 8.0 6.8 4 3 5 9 9 9 2 TNF receptor-associated factor BIRC3 binding domain ATG16 PF08614.11 EGR33187.1 - 0.014 15.7 10.4 0.014 15.7 10.4 7.1 1 1 6 7 7 7 0 Autophagy protein 16 (ATG16) BLOC1_2 PF10046.9 EGR33187.1 - 0.017 15.4 14.6 0.017 15.4 14.6 8.3 1 1 7 8 8 8 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1192 PF06698.11 EGR33187.1 - 0.1 12.7 35.4 0.43 10.7 0.3 8.1 5 3 4 9 9 9 0 Protein of unknown function (DUF1192) Myosin_tail_1 PF01576.19 EGR33187.1 - 0.18 9.5 99.5 0.91 7.2 24.1 3.8 1 1 2 3 3 3 0 Myosin tail CEP63 PF17045.5 EGR33187.1 - 1.1 9.1 102.9 0.15 11.9 8.4 6.2 2 1 2 5 5 4 0 Centrosomal protein of 63 kDa ADIP PF11559.8 EGR33187.1 - 1.7 8.7 112.5 0.28 11.3 9.9 8.1 1 1 7 8 8 8 0 Afadin- and alpha -actinin-Binding Tropomyosin_1 PF12718.7 EGR33187.1 - 6.4 6.9 108.3 0.11 12.7 8.3 7.0 1 1 5 6 6 6 0 Tropomyosin like JmjC PF02373.22 EGR33188.1 - 1.1e-32 112.8 0.1 1.1e-32 112.8 0.1 3.4 4 0 0 4 4 4 1 JmjC domain, hydroxylase JmjN PF02375.17 EGR33188.1 - 3.1e-08 33.4 0.5 9.7e-08 31.8 0.5 2.0 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 EGR33188.1 - 2.2e-05 24.7 19.2 5.4e-05 23.5 19.2 1.7 1 0 0 1 1 1 1 C5HC2 zinc finger cNMP_binding PF00027.29 EGR33189.1 - 2.6e-15 56.2 0.0 4.8e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGR33189.1 - 7.8e-15 54.6 2.3 1.6e-14 53.6 2.3 1.5 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGR33189.1 - 3.2e-14 52.7 11.7 3.2e-14 52.7 11.7 1.6 2 0 0 2 2 2 1 Ion transport protein DIOX_N PF14226.6 EGR33191.1 - 5e-07 30.5 0.0 7.9e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGR33191.1 - 0.0059 17.1 0.0 0.011 16.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhoLip_ATPase_C PF16212.5 EGR33192.1 - 1.8e-63 214.6 28.5 1.8e-63 214.6 28.5 3.1 2 1 1 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EGR33192.1 - 1.3e-11 45.2 0.0 9e-05 22.8 0.0 3.1 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGR33192.1 - 6.9e-08 32.5 1.3 7.3e-06 26.0 0.0 3.3 3 0 0 3 3 3 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGR33192.1 - 1.9e-05 24.3 0.8 4.9e-05 22.9 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGR33192.1 - 0.25 11.0 17.3 0.016 15.0 6.2 3.7 2 2 0 2 2 2 0 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 EGR33192.1 - 0.76 9.5 21.7 2.2 7.9 1.0 2.8 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus DnaJ PF00226.31 EGR33193.1 - 1.4e-25 89.1 4.3 1.4e-25 89.1 4.3 2.7 3 0 0 3 3 3 1 DnaJ domain CDC45 PF02724.14 EGR33194.1 - 1.2e-167 559.1 19.9 1.4e-167 558.9 19.9 1.0 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 EGR33194.1 - 0.1 12.0 30.1 0.17 11.3 30.1 1.3 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 EGR33194.1 - 0.48 9.1 9.9 1 8.0 9.9 1.6 1 0 0 1 1 1 0 Presenilin YL1 PF05764.13 EGR33194.1 - 0.59 10.2 27.2 1.2 9.2 27.2 1.4 1 0 0 1 1 1 0 YL1 nuclear protein Nop14 PF04147.12 EGR33194.1 - 1.5 6.9 32.0 0.096 10.9 26.5 1.6 2 0 0 2 2 2 0 Nop14-like family CDC27 PF09507.10 EGR33194.1 - 2 7.7 24.8 4.2 6.7 24.8 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Cwf_Cwc_15 PF04889.12 EGR33194.1 - 4.7 6.9 29.4 9.6 5.9 29.4 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Sporozoite_P67 PF05642.11 EGR33194.1 - 8.8 4.3 20.1 13 3.7 20.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Ion_trans PF00520.31 EGR33195.1 - 5.4e-147 487.6 102.1 3.3e-61 206.6 19.8 5.3 4 1 0 4 4 4 3 Ion transport protein PKD_channel PF08016.12 EGR33195.1 - 0.00028 19.7 92.5 0.00048 18.9 18.4 8.0 6 3 2 8 8 8 5 Polycystin cation channel ComC PF03047.14 EGR33195.1 - 5 7.0 11.1 5.4 6.9 0.9 4.8 3 0 0 3 3 3 0 COMC family tRNA-synt_2c PF01411.19 EGR33197.1 - 1.4e-31 109.7 0.0 9.6e-25 87.1 0.0 2.3 1 1 1 2 2 2 2 tRNA synthetases class II (A) tRNA-synt_2e PF02091.15 EGR33197.1 - 0.0022 17.3 0.6 0.0033 16.7 0.6 1.2 1 0 0 1 1 1 1 Glycyl-tRNA synthetase alpha subunit Dynein_light PF01221.18 EGR33198.1 - 4.9e-30 103.7 0.6 5.5e-30 103.5 0.6 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 TTL PF03133.15 EGR33199.1 - 7.5e-57 192.7 15.7 4.7e-45 154.0 2.4 2.9 3 0 0 3 3 3 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR33199.1 - 4.2e-09 36.0 11.1 2.7e-06 26.8 0.0 4.1 3 1 1 4 4 4 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR33199.1 - 3.8e-08 32.9 0.0 0.0069 15.7 0.0 2.6 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp ATP-grasp_3 PF02655.14 EGR33199.1 - 0.00047 20.2 0.2 0.0055 16.8 0.0 2.5 3 0 0 3 3 3 1 ATP-grasp domain p25-alpha PF05517.12 EGR33199.1 - 0.0037 17.5 0.7 0.0037 17.5 0.7 2.6 3 0 0 3 3 3 1 p25-alpha RimK PF08443.11 EGR33199.1 - 0.013 15.1 3.8 1.9 8.0 0.1 3.1 3 0 0 3 3 3 0 RimK-like ATP-grasp domain E2F_TDP PF02319.20 EGR33200.1 - 2.8e-24 84.9 1.4 2.8e-24 84.9 1.4 2.5 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain E2F_CC-MB PF16421.5 EGR33200.1 - 3.9e-23 81.6 1.5 3.9e-23 81.6 1.5 3.7 3 1 2 5 5 5 1 E2F transcription factor CC-MB domain DUF3018 PF11455.8 EGR33200.1 - 0.0071 16.3 0.3 0.024 14.6 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3018) a_DG1_N2 PF18424.1 EGR33200.1 - 0.025 14.7 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Alpha-Dystroglycan N-terminal domain 2 TrmB PF01978.19 EGR33200.1 - 0.031 14.2 0.1 0.059 13.3 0.1 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF4446 PF14584.6 EGR33200.1 - 0.039 13.9 0.9 0.039 13.9 0.9 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF4446) B-block_TFIIIC PF04182.12 EGR33200.1 - 0.049 13.8 0.1 0.049 13.8 0.1 2.5 2 1 0 2 2 2 0 B-block binding subunit of TFIIIC DUF4381 PF14316.6 EGR33200.1 - 0.52 10.5 0.0 0.52 10.5 0.0 2.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4381) RP-C_C PF11800.8 EGR33200.1 - 3.7 7.6 14.1 3.6 7.6 5.8 2.5 2 0 0 2 2 2 0 Replication protein C C-terminal region Dynein_light PF01221.18 EGR33201.1 - 1.1e-12 48.1 0.5 1.7e-12 47.5 0.5 1.3 1 0 0 1 1 1 1 Dynein light chain type 1 Tfb2 PF03849.14 EGR33202.1 - 0.001 18.1 2.1 0.0012 17.9 2.1 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Pkinase PF00069.25 EGR33203.1 - 1.6e-59 201.5 4.0 2e-59 201.1 4.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33203.1 - 9.5e-31 107.0 0.3 1.3e-30 106.6 0.3 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33203.1 - 1.2e-06 28.0 0.2 2.2e-06 27.2 0.2 1.5 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR33203.1 - 0.00033 19.6 0.4 0.0047 15.8 0.0 2.0 1 1 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 EGR33203.1 - 0.00085 19.0 2.9 0.002 17.7 2.9 1.6 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 EGR33203.1 - 0.0034 17.3 0.0 0.0046 16.9 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR33203.1 - 0.0069 15.8 0.9 0.012 14.9 0.9 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ODR4-like PF14778.6 EGR33203.1 - 0.041 12.8 0.1 0.057 12.4 0.1 1.2 1 0 0 1 1 1 0 Olfactory receptor 4-like TauE PF01925.19 EGR33204.1 - 0.0033 17.1 3.0 0.013 15.2 1.9 1.9 1 1 1 2 2 2 1 Sulfite exporter TauE/SafE DUF308 PF03729.13 EGR33204.1 - 0.0034 17.7 5.2 0.021 15.1 0.1 2.7 2 1 0 2 2 2 1 Short repeat of unknown function (DUF308) DUF1129 PF06570.11 EGR33204.1 - 0.0073 15.8 2.6 0.093 12.2 1.3 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF1129) COX1 PF00115.20 EGR33204.1 - 0.01 14.7 1.6 0.013 14.3 1.6 1.2 1 0 0 1 1 1 0 Cytochrome C and Quinol oxidase polypeptide I 7TMR-DISM_7TM PF07695.11 EGR33204.1 - 0.094 12.6 17.7 0.25 11.2 14.8 2.3 1 1 0 2 2 2 0 7TM diverse intracellular signalling TctA PF01970.16 EGR33204.1 - 0.65 8.7 8.7 0.56 8.9 1.9 2.2 1 1 1 2 2 2 0 Tripartite tricarboxylate transporter TctA family DHHC PF01529.20 EGR33204.1 - 4.3 7.4 8.3 1.8 8.7 2.1 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF3021 PF11457.8 EGR33204.1 - 8.1 6.8 13.6 4.2 7.7 7.8 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3021) DUF2724 PF10893.8 EGR33205.1 - 0.083 12.7 0.1 0.27 11.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) Ectoine_synth PF06339.12 EGR33206.1 - 0.031 14.5 0.0 0.031 14.5 0.0 1.6 2 0 0 2 2 2 0 Ectoine synthase HTH_28 PF13518.6 EGR33207.1 - 3.7e-05 23.7 0.0 4.1e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Helix-turn-helix domain LZ_Tnp_IS481 PF13011.6 EGR33207.1 - 0.017 15.6 0.0 0.017 15.6 0.0 1.0 1 0 0 1 1 1 0 leucine-zipper of insertion element IS481 HTH_56 PF18662.1 EGR33207.1 - 0.044 13.9 0.9 0.044 13.8 0.9 1.1 1 0 0 1 1 1 0 Cch helix turn helix domain MerR_1 PF13411.6 EGR33207.1 - 0.074 13.2 0.0 0.079 13.1 0.0 1.1 1 0 0 1 1 1 0 MerR HTH family regulatory protein HTH_29 PF13551.6 EGR33207.1 - 0.09 12.8 0.0 0.097 12.7 0.0 1.1 1 0 0 1 1 1 0 Winged helix-turn helix MBOAT PF03062.19 EGR33208.1 - 2.2e-21 76.6 26.1 2.2e-21 76.6 26.1 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MscS_porin PF12795.7 EGR33208.1 - 1.2 8.7 15.3 1.6 8.2 15.3 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain ATP-synt_F PF01990.17 EGR33209.1 - 1.1e-27 96.1 0.6 1.3e-27 95.9 0.6 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit CobU PF02283.16 EGR33211.1 - 0.044 13.4 0.2 0.2 11.2 0.2 2.1 1 0 0 1 1 1 0 Cobinamide kinase / cobinamide phosphate guanyltransferase Proteasome PF00227.26 EGR33212.1 - 1.1e-35 122.9 0.0 1.3e-35 122.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Aa_trans PF01490.18 EGR33213.1 - 2.4e-27 95.7 40.1 2.4e-27 95.7 40.1 1.7 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein VIT1 PF01988.19 EGR33213.1 - 0.14 12.0 0.0 0.69 9.7 0.0 2.2 2 1 0 2 2 2 0 VIT family MMTV_SAg PF01054.17 EGR33213.1 - 0.23 11.0 3.8 0.086 12.4 0.7 1.8 2 0 0 2 2 2 0 Mouse mammary tumour virus superantigen BRCT_2 PF16589.5 EGR33213.1 - 2.9 8.4 8.3 0.69 10.4 3.8 2.4 2 0 0 2 2 2 0 BRCT domain, a BRCA1 C-terminus domain WD40 PF00400.32 EGR33214.1 - 7.4e-17 61.4 0.2 0.00062 20.5 0.1 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR33214.1 - 0.0009 19.5 0.0 0.33 11.3 0.0 4.5 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DnaJ PF00226.31 EGR33215.1 - 1.5e-06 28.2 0.6 1.5e-06 28.2 0.6 2.0 2 0 0 2 2 2 1 DnaJ domain DNA_pol_alpha_N PF12254.8 EGR33217.1 - 0.88 9.7 6.0 2.5 8.3 1.1 2.6 2 1 1 3 3 3 0 DNA polymerase alpha subunit p180 N terminal RCC1 PF00415.18 EGR33218.1 - 5.9e-59 196.5 25.9 2.2e-14 53.8 0.1 8.5 7 2 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR33218.1 - 5.2e-43 144.0 32.5 3.8e-09 36.1 0.1 8.4 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat Kelch_6 PF13964.6 EGR33218.1 - 0.0014 18.8 5.7 5.3 7.5 0.2 4.6 4 0 0 4 4 4 2 Kelch motif Kelch_2 PF07646.15 EGR33218.1 - 0.047 13.7 1.2 2.3 8.3 0.1 3.3 3 0 0 3 3 3 0 Kelch motif NosL PF05573.12 EGR33218.1 - 0.09 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 NosL NHL PF01436.21 EGR33218.1 - 2.7 8.2 5.4 47 4.3 0.1 4.2 4 0 0 4 4 4 0 NHL repeat Ribosomal_S13 PF00416.22 EGR33219.1 - 1.4e-45 154.8 0.3 1.6e-45 154.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 Period_C PF12114.8 EGR33219.1 - 0.0051 16.4 0.0 0.0074 15.9 0.0 1.3 1 0 0 1 1 1 1 Period protein 2/3C-terminal region IMS_HHH PF11798.8 EGR33219.1 - 0.093 13.1 0.2 0.35 11.3 0.1 2.0 2 0 0 2 2 2 0 IMS family HHH motif DUF1188 PF06690.11 EGR33219.1 - 0.1 12.1 0.2 0.85 9.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1188) FbpA PF05833.11 EGR33219.1 - 0.12 11.1 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) WD40 PF00400.32 EGR33220.1 - 2.2e-10 40.9 0.2 0.0019 19.0 0.0 3.5 3 0 0 3 3 3 2 WD domain, G-beta repeat WD40_like PF17005.5 EGR33220.1 - 0.00012 21.5 7.4 0.00012 21.5 7.4 1.7 2 0 0 2 2 2 1 WD40-like domain Beta_propel PF09826.9 EGR33220.1 - 0.002 17.1 2.3 0.0023 16.9 1.2 1.6 2 0 0 2 2 2 1 Beta propeller domain Nup160 PF11715.8 EGR33220.1 - 0.011 14.4 0.1 0.015 13.9 0.1 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGR33220.1 - 0.045 14.1 0.3 0.48 10.8 0.2 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EGR33220.1 - 0.23 11.0 0.0 0.35 10.4 0.0 1.2 1 0 0 1 1 1 0 PQQ-like domain Piezo_RRas_bdg PF12166.8 EGR33222.1 - 6.1e-47 160.9 7.3 2.8e-45 155.4 7.3 2.0 1 1 0 1 1 1 1 Piezo non-specific cation channel, R-Ras-binding domain Pkinase PF00069.25 EGR33224.1 - 3.2e-66 223.4 1.7 7e-66 222.3 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Josephin PF02099.17 EGR33224.1 - 4.5e-42 143.9 1.0 4.5e-42 143.9 1.0 3.0 3 0 0 3 3 3 1 Josephin Pkinase_Tyr PF07714.17 EGR33224.1 - 2.7e-32 112.1 1.5 6.6e-25 87.9 0.0 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR33224.1 - 6.8e-07 28.6 6.1 2e-05 23.7 1.0 2.6 2 2 0 2 2 2 2 Haspin like kinase domain APH PF01636.23 EGR33224.1 - 0.058 13.3 0.1 1.3 8.9 0.2 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1031 PF06275.11 EGR33224.1 - 0.2 11.9 2.8 0.19 12.0 0.3 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1031) MAP7 PF05672.11 EGR33224.1 - 1.9 8.2 26.3 0.019 14.6 4.4 2.5 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family UIM PF02809.20 EGR33224.1 - 3.4 7.8 6.1 31 4.8 0.1 3.5 3 0 0 3 3 3 0 Ubiquitin interaction motif TK PF00265.18 EGR33225.1 - 2.1e-62 210.1 2.1 2.4e-62 209.9 2.1 1.0 1 0 0 1 1 1 1 Thymidine kinase ATPase_2 PF01637.18 EGR33225.1 - 2.4e-05 24.3 0.8 3.1e-05 24.0 0.8 1.1 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EGR33225.1 - 5.1e-05 23.3 0.4 7.2e-05 22.8 0.4 1.2 1 0 0 1 1 1 1 AAA domain zf-C2H2_2 PF12756.7 EGR33225.1 - 0.015 15.6 0.9 1.8 8.9 0.1 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) RecA PF00154.21 EGR33225.1 - 0.054 13.0 0.0 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein Ntox21 PF15526.6 EGR33225.1 - 0.11 12.8 0.3 0.17 12.2 0.3 1.3 1 0 0 1 1 1 0 Novel toxin 21 AAA_22 PF13401.6 EGR33225.1 - 0.15 12.4 0.2 0.91 9.8 0.2 2.1 1 1 0 1 1 1 0 AAA domain Aa_trans PF01490.18 EGR33226.1 - 3.6e-22 78.7 12.6 2.1e-18 66.2 6.1 2.0 1 1 1 2 2 2 2 Transmembrane amino acid transporter protein Phage_holin_3_3 PF16083.5 EGR33226.1 - 0.00062 19.8 1.0 0.13 12.4 0.0 3.1 3 0 0 3 3 3 1 LydA holin phage, holin superfamily III DUF1948 PF09185.10 EGR33226.1 - 0.048 13.5 0.2 0.14 12.0 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1948) KH_dom-like PF14714.6 EGR33226.1 - 0.078 13.3 0.4 5.8 7.3 0.1 2.5 2 1 0 2 2 2 0 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal Tetraspanin PF00335.20 EGR33226.1 - 3.1 7.5 9.3 0.33 10.6 0.3 2.2 1 1 0 2 2 2 0 Tetraspanin family Pkinase PF00069.25 EGR33227.1 - 1.8e-19 70.1 1.0 2.1e-19 69.9 1.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33227.1 - 5.9e-11 42.1 0.5 6.4e-11 42.0 0.5 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR33227.1 - 3.9e-10 39.1 0.1 6.5e-10 38.3 0.1 1.4 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR33227.1 - 0.0029 17.6 0.0 0.0034 17.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR33227.1 - 0.0036 16.7 0.2 0.0046 16.3 0.2 1.3 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGR33227.1 - 0.015 14.9 0.0 0.026 14.1 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Asp PF00026.23 EGR33228.1 - 1.2e-22 80.7 6.3 2.6e-19 69.8 6.3 3.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGR33228.1 - 6.9e-22 78.5 2.3 6.9e-22 78.5 2.3 2.4 2 1 0 2 2 1 1 Xylanase inhibitor N-terminal Collagen PF01391.18 EGR33228.1 - 2.6e-09 36.7 48.9 6.9e-05 22.5 22.1 3.1 1 1 2 3 3 3 3 Collagen triple helix repeat (20 copies) TAXi_C PF14541.6 EGR33228.1 - 5.7e-07 29.4 0.5 1.2e-06 28.4 0.5 1.5 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal DUF1180 PF06679.12 EGR33228.1 - 0.0026 18.2 7.0 0.22 11.9 7.0 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1180) LAP1C PF05609.12 EGR33228.1 - 0.0035 16.5 12.4 0.0054 15.9 12.4 1.2 1 0 0 1 1 1 1 Lamina-associated polypeptide 1C (LAP1C) DUF4834 PF16118.5 EGR33228.1 - 0.011 16.7 4.5 0.011 16.7 4.5 4.9 2 1 1 3 3 1 0 Domain of unknown function (DUF4834) Sigma_reg_N PF13800.6 EGR33228.1 - 0.047 14.0 3.3 0.17 12.2 3.3 2.0 1 0 0 1 1 1 0 Sigma factor regulator N-terminal TMEM51 PF15345.6 EGR33228.1 - 0.054 13.3 8.4 0.16 11.8 8.1 2.1 1 1 0 1 1 1 0 Transmembrane protein 51 SCIMP PF15050.6 EGR33228.1 - 0.072 13.6 1.7 0.16 12.5 1.7 1.5 1 0 0 1 1 1 0 SCIMP protein MPS-4 PF17523.2 EGR33228.1 - 0.091 12.9 0.6 0.24 11.5 0.0 2.0 2 0 0 2 2 2 0 MinK-related peptide, potassium channel accessory sub-unit protein 4 Kei1 PF08552.11 EGR33228.1 - 0.11 12.3 0.4 0.25 11.2 0.1 1.7 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 TMEM154 PF15102.6 EGR33228.1 - 0.16 11.9 11.6 0.13 12.2 9.3 2.2 1 1 0 1 1 1 0 TMEM154 protein family Cadherin_C_2 PF16492.5 EGR33228.1 - 0.28 12.0 0.1 0.28 12.0 0.1 2.6 2 0 0 2 2 1 0 Cadherin cytoplasmic C-terminal Utp14 PF04615.13 EGR33228.1 - 3.9 5.9 19.8 5.9 5.3 19.8 1.2 1 0 0 1 1 1 0 Utp14 protein S-AdoMet_synt_C PF02773.16 EGR33229.1 - 2.8 7.9 5.6 0.46 10.5 1.0 2.0 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, C-terminal domain Ribosomal_L18A PF01775.17 EGR33230.1 - 6.2e-13 48.9 0.2 3.3e-06 27.2 0.1 2.4 1 1 1 2 2 2 2 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Ribosomal_L23eN PF03939.13 EGR33230.1 - 0.12 12.6 1.8 0.18 12.0 0.5 2.0 1 1 1 2 2 2 0 Ribosomal protein L23, N-terminal domain U-box PF04564.15 EGR33231.1 - 1.5e-10 41.1 0.1 1.7e-10 40.9 0.1 1.1 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EGR33231.1 - 6.4e-09 35.5 0.1 2.8e-08 33.5 0.1 1.9 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Rtf2 PF04641.12 EGR33231.1 - 0.00013 21.4 0.0 0.00013 21.4 0.0 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-NOSIP PF15906.5 EGR33231.1 - 0.017 15.2 0.0 0.025 14.7 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 EGR33231.1 - 0.018 15.1 0.0 0.032 14.3 0.0 1.5 1 1 0 1 1 1 0 RING-type zinc-finger PT-TG PF14449.6 EGR33231.1 - 0.15 12.0 0.3 1.8 8.5 0.0 2.0 2 0 0 2 2 2 0 Pre-toxin TG WD40 PF00400.32 EGR33232.1 - 0.0033 18.2 0.1 3.3 8.7 0.0 3.3 3 1 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR33232.1 - 0.01 16.1 0.0 0.022 15.1 0.0 1.6 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain 5_nucleotid_C PF02872.18 EGR33233.1 - 5.1e-12 46.3 0.2 1.4e-11 44.9 0.2 1.8 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain WD40 PF00400.32 EGR33235.1 - 4.8e-25 87.3 3.0 2.3e-07 31.4 0.1 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR33235.1 - 1.5e-06 28.4 1.3 0.00066 19.9 0.1 3.2 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGR33235.1 - 0.061 12.1 2.0 1.4 7.5 0.1 2.8 1 1 1 3 3 3 0 Nup133 N terminal like Sec63 PF02889.16 EGR33236.1 - 2.5e-56 190.7 6.9 4e-40 137.6 1.3 3.0 4 0 0 4 4 4 2 Sec63 Brl domain DEAD PF00270.29 EGR33236.1 - 7.9e-19 68.1 2.0 1.2e-18 67.5 0.3 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EGR33236.1 - 1.1e-10 41.8 1.2 1.1e-10 41.8 1.2 2.8 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGR33236.1 - 0.017 15.4 1.2 0.079 13.2 0.3 2.6 2 1 0 2 2 2 0 AAA domain DUF2124 PF09897.9 EGR33236.1 - 0.023 14.6 0.1 0.086 12.7 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2124) AAA_25 PF13481.6 EGR33236.1 - 0.034 13.7 0.0 0.92 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 EGR33236.1 - 0.056 12.5 0.0 0.15 11.1 0.0 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 EGR33236.1 - 0.095 13.0 0.1 0.34 11.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain DnaB_C PF03796.15 EGR33236.1 - 0.097 12.0 3.1 0.046 13.1 0.3 1.8 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain PerB PF06590.11 EGR33236.1 - 1.8 9.1 6.5 1.2 9.6 0.6 3.0 3 0 0 3 3 3 0 PerB protein Sec63 PF02889.16 EGR33237.1 - 5.2e-49 166.7 0.0 9.9e-49 165.8 0.0 1.5 1 0 0 1 1 1 1 Sec63 Brl domain Helicase_PWI PF18149.1 EGR33237.1 - 6.4e-36 122.9 10.4 7.5e-36 122.7 3.9 3.2 2 0 0 2 2 2 1 N-terminal helicase PWI domain DEAD PF00270.29 EGR33237.1 - 3.8e-27 95.2 0.5 1.4e-26 93.3 0.5 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGR33237.1 - 6.5e-14 52.3 0.1 6.5e-14 52.3 0.1 3.6 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGR33237.1 - 1.9e-09 37.9 2.3 2.8e-07 30.9 0.0 4.2 3 1 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGR33237.1 - 0.003 17.8 0.1 0.02 15.2 0.1 2.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGR33237.1 - 0.018 14.8 0.0 0.018 14.8 0.0 4.2 2 1 0 3 3 3 0 AAA domain DUF2258 PF10015.9 EGR33237.1 - 0.15 12.2 1.2 5.5 7.2 0.2 3.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2258) MFS_1 PF07690.16 EGR33238.1 - 9.2e-39 133.4 36.2 8.9e-25 87.4 16.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGR33238.1 - 2e-09 36.8 25.8 2.7e-05 23.2 14.5 2.8 1 1 2 3 3 3 2 Sugar (and other) transporter PUCC PF03209.15 EGR33238.1 - 0.0003 19.9 0.2 0.00076 18.6 0.0 1.9 2 1 0 2 2 2 1 PUCC protein GPI2 PF06432.11 EGR33238.1 - 0.72 9.2 14.2 0.64 9.4 0.2 3.8 3 1 1 4 4 4 0 Phosphatidylinositol N-acetylglucosaminyltransferase Ion_trans PF00520.31 EGR33240.1 - 1.9e-16 60.0 39.8 6.7e-16 58.3 24.0 2.3 2 0 0 2 2 2 2 Ion transport protein Ion_trans_2 PF07885.16 EGR33240.1 - 6.5e-11 42.0 9.6 6.5e-11 42.0 9.6 3.5 3 1 0 3 3 3 1 Ion channel cNMP_binding PF00027.29 EGR33240.1 - 4.3e-10 39.5 0.0 7.5e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Sec1 PF00995.23 EGR33241.1 - 3.1e-93 314.0 28.4 3.6e-93 313.8 28.4 1.0 1 0 0 1 1 1 1 Sec1 family Biopterin_H PF00351.21 EGR33242.1 - 3.8e-101 338.4 1.8 5.3e-101 338.0 1.8 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase Cellulase PF00150.18 EGR33243.1 - 1e-28 100.6 0.0 2e-28 99.6 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) FtsJ PF01728.19 EGR33243.1 - 9.2e-15 55.2 0.1 2.1e-14 54.0 0.1 1.7 1 1 1 2 2 2 1 FtsJ-like methyltransferase Glyco_hydro_5_C PF18564.1 EGR33243.1 - 7.7e-10 39.2 0.0 1.4e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_42 PF02449.15 EGR33243.1 - 5.4e-05 22.7 0.5 0.0003 20.3 0.0 2.2 2 1 0 2 2 2 1 Beta-galactosidase Glyco_hydro_35 PF01301.19 EGR33243.1 - 0.0011 18.7 0.0 0.0021 17.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Rdx PF10262.9 EGR33244.1 - 1.9e-06 27.9 0.7 1.3e-05 25.3 0.7 2.1 1 1 0 1 1 1 1 Rdx family Phage_Gp23 PF10669.9 EGR33244.1 - 0.071 13.4 0.7 0.11 12.8 0.7 1.2 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) HhH-GPD PF00730.25 EGR33245.1 - 9e-09 35.8 1.1 2e-08 34.6 1.1 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGR33245.1 - 1.8e-06 27.5 0.0 5e-06 26.1 0.0 1.8 2 0 0 2 2 2 1 Helix-hairpin-helix motif DUF763 PF05559.11 EGR33245.1 - 0.0072 15.5 1.2 0.0072 15.5 1.2 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF763) HHH_2 PF12826.7 EGR33245.1 - 0.012 15.6 0.2 0.048 13.8 0.0 2.1 2 1 0 2 2 2 0 Helix-hairpin-helix motif HHH_5 PF14520.6 EGR33245.1 - 0.018 15.7 0.4 0.16 12.6 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain MAF_flag10 PF01973.18 EGR33245.1 - 0.058 13.1 0.4 0.058 13.1 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function DUF115 PIN_12 PF16289.5 EGR33245.1 - 8.5 6.8 16.1 0.32 11.5 5.2 2.1 2 0 0 2 2 2 0 PIN domain Pkinase PF00069.25 EGR33246.1 - 2.2e-10 40.4 0.0 2.5e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33246.1 - 0.0064 15.8 0.0 0.0064 15.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGR33247.1 - 1.7e-31 109.6 1.2 1.8e-31 109.4 1.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33247.1 - 2.8e-18 66.1 0.3 3.2e-18 66.0 0.3 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33247.1 - 2e-05 24.1 0.0 3.2e-05 23.4 0.0 1.2 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR33247.1 - 4.6e-05 22.9 0.0 7.6e-05 22.1 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR33247.1 - 7e-05 22.9 0.1 0.00054 20.0 0.3 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGR33247.1 - 0.00062 18.8 0.2 0.00076 18.5 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGR33247.1 - 0.0014 17.5 0.1 0.0018 17.2 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EGR33247.1 - 0.0019 17.3 0.3 0.0031 16.6 0.1 1.4 1 1 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 EGR33247.1 - 0.02 14.5 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 EGR33247.1 - 0.056 13.1 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 Cyclin_N PF00134.23 EGR33248.1 - 2.7e-24 85.3 0.5 2.7e-24 85.3 0.5 2.3 3 0 0 3 3 3 1 Cyclin, N-terminal domain PP2C PF00481.21 EGR33249.1 - 3.4e-70 236.6 0.0 4.3e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGR33249.1 - 0.13 12.1 0.0 1.6 8.6 0.0 2.0 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) PX PF00787.24 EGR33250.1 - 1.6e-18 66.7 0.3 4.9e-18 65.2 0.3 1.8 1 0 0 1 1 1 1 PX domain WD40 PF00400.32 EGR33250.1 - 7.4e-14 51.9 2.0 0.00044 21.0 0.0 5.9 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR33250.1 - 2.2e-10 40.7 0.7 1.9e-05 24.8 0.1 4.6 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Rotavirus_VP7 PF05868.11 EGR33250.1 - 0.0041 16.5 1.1 0.6 9.4 0.1 2.4 1 1 1 2 2 2 2 Rotavirus major outer capsid protein VP7 Lactonase PF10282.9 EGR33250.1 - 0.05 12.9 0.0 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.6 EGR33250.1 - 0.13 12.8 0.0 10 6.7 0.0 3.0 2 0 0 2 2 2 0 PQQ-like domain 14-3-3 PF00244.20 EGR33251.1 - 4.8e-80 268.2 11.9 6.4e-79 264.5 11.9 1.9 1 1 0 1 1 1 1 14-3-3 protein TPR_12 PF13424.6 EGR33251.1 - 0.00058 20.1 0.4 0.072 13.4 0.1 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat DUF3384 PF11864.8 EGR33251.1 - 0.002 17.1 0.4 0.0027 16.7 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3384) ABC_membrane PF00664.23 EGR33251.1 - 0.3 10.7 0.2 1.2 8.7 0.3 1.9 2 0 0 2 2 2 0 ABC transporter transmembrane region Pkinase PF00069.25 EGR33252.1 - 3.4e-59 200.4 3.0 3.4e-59 200.4 3.0 2.0 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33252.1 - 5e-44 150.5 0.7 8.9e-44 149.7 0.7 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR33252.1 - 0.00044 19.1 0.2 0.0015 17.4 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGR33252.1 - 0.014 15.3 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family cNMP_binding PF00027.29 EGR33253.1 - 2.8e-29 101.0 0.4 4.1e-16 58.8 0.1 3.4 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain DUF5442 PF17514.2 EGR33253.1 - 0.0038 17.4 0.6 0.0038 17.4 0.6 3.1 3 1 0 3 3 3 1 Family of unknown function (DUF5442) Uteroglobin PF01099.17 EGR33253.1 - 4.8 7.6 9.6 9.3 6.7 0.1 4.6 5 0 0 5 5 5 0 Uteroglobin family Hist_deacetyl PF00850.19 EGR33254.1 - 7.7e-79 265.4 0.0 1.1e-78 264.9 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain HEPN PF05168.14 EGR33254.1 - 0.033 14.3 0.1 0.19 11.9 0.1 2.1 2 0 0 2 2 2 0 HEPN domain GA PF01468.17 EGR33254.1 - 2.6 8.4 6.7 6.8 7.0 0.6 2.4 2 0 0 2 2 2 0 GA module Kelch_1 PF01344.25 EGR33255.1 - 3.1e-37 125.9 5.3 8.9e-12 44.4 0.0 4.4 4 0 0 4 4 4 4 Kelch motif Kelch_6 PF13964.6 EGR33255.1 - 5.5e-28 96.3 3.0 2.9e-08 33.7 0.0 4.1 2 1 2 4 4 4 3 Kelch motif Kelch_4 PF13418.6 EGR33255.1 - 4.9e-20 71.3 6.0 1.3e-07 31.5 0.1 4.1 3 1 1 4 4 4 4 Galactose oxidase, central domain Kelch_3 PF13415.6 EGR33255.1 - 3.8e-17 62.1 0.1 6.9e-05 23.0 0.0 4.0 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.15 EGR33255.1 - 2.6e-14 52.5 4.7 0.00064 19.6 0.1 4.2 4 0 0 4 4 4 3 Kelch motif Kelch_5 PF13854.6 EGR33255.1 - 8.3e-12 44.8 4.2 0.01 15.8 0.2 4.2 4 0 0 4 4 4 3 Kelch motif Dehydratase_LU PF02286.15 EGR33255.1 - 0.19 10.3 0.1 0.3 9.6 0.1 1.3 1 0 0 1 1 1 0 Dehydratase large subunit DUF3668 PF12416.8 EGR33256.1 - 0.0015 18.4 0.1 0.0038 17.1 0.1 1.6 1 0 0 1 1 1 1 Cep120 protein Hydrolase PF00702.26 EGR33257.1 - 1.5e-13 51.6 0.2 4e-06 27.3 0.0 2.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGR33257.1 - 2.7e-05 24.2 0.0 5.8e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 EGR33257.1 - 0.0035 17.1 10.1 0.0059 16.3 10.1 1.3 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus GWT1 PF06423.12 EGR33257.1 - 0.015 15.4 5.3 0.015 15.4 5.3 2.5 2 1 0 2 2 2 0 GWT1 DUF2812 PF11193.8 EGR33257.1 - 0.08 13.2 0.2 0.47 10.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2812) Pkinase PF00069.25 EGR33258.1 - 3.3e-66 223.3 0.0 5.4e-66 222.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33258.1 - 1.1e-34 119.9 4.6 8.4e-27 94.1 0.5 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR33258.1 - 1.9e-06 27.1 0.2 3.5e-06 26.2 0.2 1.5 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EGR33258.1 - 0.0015 18.1 0.3 0.0055 16.3 0.1 2.0 1 1 1 2 2 2 1 RIO1 family APH PF01636.23 EGR33258.1 - 0.0043 17.0 0.2 0.12 12.2 0.2 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGR33258.1 - 0.019 14.3 0.3 3 7.1 0.0 2.4 1 1 0 2 2 2 0 Kinase-like Pox_ser-thr_kin PF05445.11 EGR33258.1 - 0.021 13.8 0.0 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase FAD_binding_7 PF03441.14 EGR33259.1 - 1e-71 240.6 3.6 2.1e-68 229.8 3.0 2.1 1 1 1 2 2 2 2 FAD binding domain of DNA photolyase Pkinase PF00069.25 EGR33260.1 - 2.8e-65 220.3 0.2 3.7e-65 219.9 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33260.1 - 1e-30 106.9 0.0 1.4e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR33260.1 - 0.006 16.0 0.0 0.015 14.7 0.0 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Myticin-prepro PF10690.9 EGR33261.1 - 0.029 14.6 0.2 0.055 13.7 0.2 1.4 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel DUF740 PF05340.12 EGR33261.1 - 0.19 10.4 5.7 0.2 10.4 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) APP_amyloid PF10515.9 EGR33261.1 - 0.34 11.4 6.4 0.21 12.1 1.1 2.1 2 0 0 2 2 2 0 Beta-amyloid precursor protein C-terminus Pkinase PF00069.25 EGR33262.1 - 1.5e-48 165.5 0.0 1.7e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33262.1 - 1.3e-26 93.4 0.0 1.7e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR33262.1 - 2.8e-05 23.1 0.0 4.1e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EGR33262.1 - 0.031 13.3 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.14 EGR33262.1 - 0.1 12.0 0.0 0.26 10.6 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family RsfS PF02410.15 EGR33263.1 - 1.5e-20 73.5 0.1 1.9e-20 73.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation MF_alpha_N PF05436.11 EGR33263.1 - 0.028 14.3 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus Adaptin_N PF01602.20 EGR33264.1 - 8.2e-86 288.6 11.7 8.2e-86 288.6 11.7 1.6 2 0 0 2 2 2 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EGR33264.1 - 3.8e-06 27.2 1.4 3.8e-06 27.2 1.4 2.2 2 0 0 2 2 2 1 Adaptin C-terminal domain HEPN_LA2681 PF18733.1 EGR33264.1 - 0.031 13.6 0.1 0.091 12.1 0.1 1.8 1 0 0 1 1 1 0 LA2681-like HEPN DHHA2 PF02833.14 EGR33264.1 - 0.069 13.3 0.2 0.23 11.6 0.1 1.9 2 0 0 2 2 2 0 DHHA2 domain RYDR_ITPR PF01365.21 EGR33264.1 - 0.095 12.1 5.4 0.18 11.2 3.0 2.4 1 1 1 2 2 2 0 RIH domain IFRD PF05004.13 EGR33264.1 - 0.67 9.0 4.7 0.39 9.8 0.2 2.4 3 0 0 3 3 3 0 Interferon-related developmental regulator (IFRD) DUF676 PF05057.14 EGR33266.1 - 5.6e-45 153.5 1.2 8.3e-45 153.0 1.2 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGR33266.1 - 3.2e-10 40.3 1.3 5.3e-09 36.3 1.3 2.0 1 1 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 EGR33266.1 - 1.6e-06 28.0 0.2 1.7e-05 24.7 0.2 2.1 1 1 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 EGR33266.1 - 0.00043 19.6 0.1 0.00061 19.1 0.1 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 EGR33266.1 - 0.005 16.4 0.1 0.015 14.8 0.1 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 EGR33266.1 - 0.0061 16.2 0.4 0.03 14.0 0.4 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Lipase_3 PF01764.25 EGR33266.1 - 0.017 15.0 0.0 0.037 13.9 0.0 1.6 1 1 0 1 1 1 0 Lipase (class 3) Hydrolase_4 PF12146.8 EGR33266.1 - 0.026 13.8 0.1 0.06 12.6 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGR33266.1 - 0.087 13.4 0.0 0.092 13.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Lipase_2 PF01674.18 EGR33266.1 - 0.12 11.9 0.0 0.27 10.7 0.0 1.7 1 1 0 1 1 1 0 Lipase (class 2) DUF3657 PF12394.8 EGR33267.1 - 9.8e-14 51.7 2.5 1.1e-13 51.5 1.1 1.9 2 0 0 2 2 2 1 Protein FAM135 EB1 PF03271.17 EGR33268.1 - 4.4e-09 36.4 1.2 4.4e-09 36.4 1.2 2.1 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 EGR33268.1 - 6.8e-09 35.9 2.5 6.8e-09 35.9 2.5 2.3 2 1 0 2 2 2 1 Calponin homology (CH) domain DUF4795 PF16043.5 EGR33268.1 - 0.051 13.2 4.0 0.077 12.6 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) IBR PF01485.21 EGR33269.1 - 3.2e-09 36.9 16.1 3.2e-09 36.9 16.1 2.7 2 1 0 2 2 2 1 IBR domain, a half RING-finger domain CAF-1_p150 PF11600.8 EGR33270.1 - 0.034 13.8 29.5 0.063 13.0 29.5 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Vfa1 PF08432.10 EGR33270.1 - 0.34 11.2 17.9 0.6 10.4 17.9 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.17 EGR33270.1 - 0.42 10.7 7.5 0.55 10.3 7.5 1.3 1 0 0 1 1 1 0 DDHD domain MAP7 PF05672.11 EGR33270.1 - 0.58 9.8 30.0 1 9.0 30.0 1.3 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family SAPS PF04499.15 EGR33270.1 - 1.1 8.0 24.9 0.17 10.6 15.8 2.1 1 1 1 2 2 2 0 SIT4 phosphatase-associated protein Neur_chan_memb PF02932.16 EGR33270.1 - 1.9 8.5 6.9 2.2 8.3 6.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CLN3 PF02487.17 EGR33270.1 - 7.1 5.6 7.6 11 5.0 7.6 1.3 1 0 0 1 1 1 0 CLN3 protein EF-hand_1 PF00036.32 EGR33271.1 - 0.0099 15.4 0.0 0.063 12.8 0.0 2.5 1 0 0 1 1 1 1 EF hand CDC50 PF03381.15 EGR33272.1 - 7.9e-55 186.3 17.7 2.2e-54 184.9 10.9 2.0 1 1 1 2 2 2 2 LEM3 (ligand-effect modulator 3) family / CDC50 family SPW PF03779.14 EGR33272.1 - 2.9 7.6 5.6 0.33 10.6 0.3 2.0 2 0 0 2 2 2 0 SPW repeat PARP PF00644.20 EGR33273.1 - 6.3e-51 172.7 0.0 6.3e-51 172.7 0.0 4.2 3 1 1 4 4 4 1 Poly(ADP-ribose) polymerase catalytic domain BING4CT PF08149.11 EGR33273.1 - 4e-31 106.6 3.2 4.6e-29 100.0 0.0 3.8 4 0 0 4 4 4 2 BING4CT (NUC141) domain PARP_reg PF02877.14 EGR33273.1 - 2.4e-20 73.0 1.5 2.4e-20 73.0 1.5 2.7 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EGR33273.1 - 1.5e-18 66.6 0.1 1.5e-18 66.6 0.1 3.4 2 1 1 3 3 3 1 WGR domain WD40 PF00400.32 EGR33273.1 - 0.0024 18.7 0.3 0.17 12.8 0.0 3.5 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR33273.1 - 0.0033 17.7 0.0 12 6.3 0.0 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGR33273.1 - 0.0044 16.4 0.0 0.01 15.2 0.0 1.6 1 0 0 1 1 1 1 WD40-like domain Kinesin PF00225.23 EGR33274.1 - 3.1e-84 282.8 2.7 3.1e-84 282.8 2.7 1.6 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGR33274.1 - 3.6e-14 52.9 0.3 3.6e-14 52.9 0.3 3.1 2 1 0 3 3 3 1 Microtubule binding AAA_24 PF13479.6 EGR33274.1 - 0.63 9.7 4.1 3.6 7.3 0.1 2.7 3 0 0 3 3 3 0 AAA domain Psb28 PF03912.14 EGR33274.1 - 2.1 8.7 7.0 1.4 9.2 0.3 2.6 2 0 0 2 2 2 0 Psb28 protein Pkinase PF00069.25 EGR33275.1 - 1.3e-67 228.0 2.5 1.3e-67 228.0 2.5 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33275.1 - 4.2e-43 147.5 0.6 6.4e-43 146.9 0.6 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33275.1 - 8e-05 22.1 0.7 0.00013 21.3 0.2 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGR33275.1 - 0.00022 21.2 0.0 0.0023 17.9 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR33275.1 - 0.00031 20.2 0.3 0.00058 19.3 0.3 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGR33275.1 - 0.0066 16.1 3.8 0.0066 16.1 3.8 2.8 3 1 0 3 3 3 1 RIO1 family Kinesin PF00225.23 EGR33276.1 - 2.7e-87 292.8 10.6 3.9e-87 292.3 10.6 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR33276.1 - 3.1e-16 59.6 7.2 3.1e-16 59.6 7.2 2.7 3 0 0 3 3 3 1 Microtubule binding DUF2521 PF10730.9 EGR33276.1 - 0.00011 22.3 0.1 0.00031 20.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2521) Pkinase PF00069.25 EGR33277.1 - 4.8e-67 226.1 1.2 6.1e-67 225.8 1.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33277.1 - 2.9e-43 148.0 0.7 3.9e-43 147.6 0.7 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33277.1 - 1.4e-05 24.6 0.4 0.00027 20.4 0.0 2.6 1 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR33277.1 - 0.0002 20.3 0.1 0.00052 18.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase ABC1 PF03109.16 EGR33277.1 - 0.00048 20.3 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 ABC1 family RIO1 PF01163.22 EGR33277.1 - 0.0013 18.4 0.9 0.005 16.5 0.9 1.9 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 EGR33277.1 - 0.011 15.6 0.0 0.65 9.9 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Pkinase PF00069.25 EGR33279.1 - 2.4e-53 181.2 2.4 4e-53 180.5 2.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33279.1 - 9e-28 97.3 0.1 1.2e-27 96.8 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Sugar_tr PF00083.24 EGR33279.1 - 3.8e-24 85.4 18.6 2.7e-18 66.1 9.2 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGR33279.1 - 9.5e-13 47.8 28.0 4.9e-12 45.5 28.0 1.9 1 1 0 1 1 1 1 Major Facilitator Superfamily Choline_kinase PF01633.20 EGR33279.1 - 0.00018 21.2 0.8 0.00043 19.9 0.8 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EGR33279.1 - 0.00036 20.0 0.2 0.00058 19.3 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR33279.1 - 0.0033 17.4 0.0 0.0094 15.9 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGR33279.1 - 0.0058 16.3 0.5 0.013 15.1 0.5 1.6 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EGR33279.1 - 0.018 14.0 1.4 0.027 13.4 1.4 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EGR33279.1 - 0.11 11.2 0.0 0.16 10.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Dynein_IC2 PF11540.8 EGR33279.1 - 0.13 12.3 0.6 0.42 10.6 0.6 1.9 1 0 0 1 1 1 0 Cytoplasmic dynein 1 intermediate chain 2 TTL PF03133.15 EGR33280.1 - 1.9e-83 280.0 1.9 1.9e-83 280.0 1.9 1.4 2 0 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR33280.1 - 4e-09 36.1 0.1 0.0001 21.7 0.0 2.6 2 1 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR33280.1 - 6.8e-05 22.2 0.1 0.011 15.1 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 EGR33280.1 - 0.0019 17.8 0.1 0.84 9.2 0.0 2.2 2 0 0 2 2 2 2 RimK-like ATP-grasp domain Pkinase PF00069.25 EGR33281.1 - 1.3e-58 198.4 2.8 1.7e-58 198.0 2.8 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33281.1 - 5.4e-27 94.7 0.4 7.3e-27 94.3 0.4 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33281.1 - 8.9e-07 28.5 0.9 1.8e-06 27.5 0.4 1.8 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 EGR33281.1 - 0.00011 21.9 2.1 0.00011 21.9 2.1 1.7 2 1 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 EGR33281.1 - 0.00038 19.4 0.0 0.00069 18.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGR33281.1 - 0.0016 17.5 2.3 0.0026 16.8 2.3 1.4 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGR33281.1 - 0.061 12.7 0.2 0.087 12.2 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SpoU_methylase PF00588.19 EGR33282.1 - 1.1e-25 90.5 0.8 9e-25 87.5 0.8 2.2 1 1 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EGR33282.1 - 2.3e-14 53.4 0.2 5.4e-14 52.2 0.2 1.7 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Nsp3_PL2pro PF12124.8 EGR33282.1 - 0.0049 16.6 0.0 0.11 12.3 0.0 2.6 3 0 0 3 3 3 1 Coronavirus polyprotein cleavage domain Isochorismatase PF00857.20 EGR33282.1 - 0.021 15.0 0.0 0.064 13.4 0.0 1.7 2 0 0 2 2 2 0 Isochorismatase family AAA_14 PF13173.6 EGR33282.1 - 0.053 13.6 0.3 0.13 12.2 0.1 2.0 2 1 0 2 2 2 0 AAA domain DUF705 PF05152.12 EGR33282.1 - 0.093 12.2 4.3 0.82 9.1 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF705) Ribosomal_L7Ae PF01248.26 EGR33282.1 - 0.32 10.7 2.1 0.51 10.1 0.5 2.1 2 0 0 2 2 2 0 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Ins145_P3_rec PF08709.11 EGR33284.1 - 2.7e-19 69.2 8.5 6.5e-18 64.7 6.7 3.6 3 1 0 3 3 3 1 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 EGR33284.1 - 5e-05 23.2 7.7 0.012 15.5 0.2 3.0 3 0 0 3 3 3 2 MIR domain Ion_trans PF00520.31 EGR33287.1 - 4e-05 23.0 24.7 4e-05 23.0 24.7 3.2 2 1 1 3 3 3 1 Ion transport protein HxlR PF01638.17 EGR33287.1 - 0.059 13.2 0.1 0.24 11.3 0.0 2.0 2 0 0 2 2 2 0 HxlR-like helix-turn-helix OTU PF02338.19 EGR33288.1 - 2.4e-19 70.1 1.3 5.1e-19 69.0 0.1 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGR33288.1 - 9.7e-05 21.9 15.3 0.00069 19.1 0.7 3.1 2 1 1 3 3 3 2 Peptidase C65 Otubain UBA PF00627.31 EGR33288.1 - 0.04 13.8 0.3 0.21 11.5 0.0 2.3 2 0 0 2 2 2 0 UBA/TS-N domain DUF3533 PF12051.8 EGR33288.1 - 1.2 8.0 4.3 1.6 7.6 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) DUF2684 PF10885.8 EGR33289.1 - 0.079 13.1 0.6 0.079 13.1 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2684) NAC PF01849.18 EGR33290.1 - 3.6e-21 74.9 0.6 8.1e-21 73.8 0.6 1.6 1 0 0 1 1 1 1 NAC domain Ion_trans PF00520.31 EGR33291.1 - 1.6e-211 698.9 132.3 3.1e-58 196.9 20.0 4.5 4 0 0 4 4 4 4 Ion transport protein PKD_channel PF08016.12 EGR33291.1 - 5.4e-20 71.5 113.1 2.8e-09 36.1 20.7 9.6 8 2 2 10 10 10 8 Polycystin cation channel SHE3 PF17078.5 EGR33292.1 - 0.0026 17.5 21.0 0.0026 17.5 21.0 4.1 1 1 3 4 4 4 1 SWI5-dependent HO expression protein 3 GAS PF13851.6 EGR33293.1 - 1.5e-10 40.8 140.4 0.022 14.1 10.4 9.5 1 1 7 8 8 8 7 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 EGR33293.1 - 7.1e-09 36.2 121.2 0.09 13.0 12.1 9.3 1 1 7 8 8 8 5 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 EGR33293.1 - 1.2e-06 27.5 130.2 0.0015 17.3 25.5 5.9 1 1 5 6 6 6 5 AAA domain DHR10 PF18595.1 EGR33293.1 - 2.1e-05 24.6 137.8 0.00093 19.2 9.3 9.7 1 1 8 9 9 9 5 Designed helical repeat protein 10 domain Atg14 PF10186.9 EGR33293.1 - 0.0044 16.2 22.2 0.0044 16.2 22.2 7.6 1 1 5 6 6 5 2 Vacuolar sorting 38 and autophagy-related subunit 14 Herpes_ICP4_N PF03584.15 EGR33293.1 - 0.011 15.5 14.2 1.6 8.6 0.1 5.2 6 0 0 6 6 6 0 Herpesvirus ICP4-like protein N-terminal region YqzH PF14164.6 EGR33293.1 - 0.021 14.9 6.6 36 4.5 0.1 6.1 4 0 0 4 4 4 0 YqzH-like protein DUF4389 PF14333.6 EGR33293.1 - 0.041 13.8 0.8 27 4.8 0.0 5.2 7 0 0 7 7 7 0 Domain of unknown function (DUF4389) DUF4342 PF14242.6 EGR33293.1 - 0.11 12.5 1.0 40 4.3 0.1 3.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) HMMR_N PF15905.5 EGR33293.1 - 0.13 11.7 166.3 0.12 11.8 8.0 8.0 1 1 7 8 8 7 0 Hyaluronan mediated motility receptor N-terminal Filament PF00038.21 EGR33293.1 - 0.22 11.1 144.3 2.5 7.6 45.9 9.1 1 1 3 4 4 4 0 Intermediate filament protein BLOC1_2 PF10046.9 EGR33293.1 - 3.2 8.1 126.4 0.14 12.4 2.5 12.4 2 2 9 12 12 12 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AvrLm4-7 PF18661.1 EGR33293.1 - 9.1 7.4 12.5 37 5.4 0.4 4.9 3 1 0 3 3 3 0 Avirulence Effector AvrLm4-7 Ank_4 PF13637.6 EGR33296.1 - 4e-15 56.0 0.8 1.6e-08 34.9 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGR33296.1 - 8.8e-15 54.6 0.0 6.5e-08 32.7 0.0 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGR33296.1 - 1.7e-13 51.0 0.2 1.1e-12 48.4 0.2 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGR33296.1 - 1.1e-11 44.6 0.0 1.6e-05 25.1 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EGR33296.1 - 4.5e-11 42.0 0.0 0.00072 19.8 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeat UCH PF00443.29 EGR33297.1 - 8.6e-27 94.2 8.2 8.6e-27 94.2 8.2 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase tRNA-synt_2b PF00587.25 EGR33298.1 - 1.1e-36 126.5 0.0 1.6e-36 126.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EGR33298.1 - 1.5e-17 63.8 13.8 2.8e-17 62.9 13.8 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain DUF3450 PF11932.8 EGR33298.1 - 0.015 14.6 4.0 0.024 14.0 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Ribosomal_L30 PF00327.20 EGR33299.1 - 1.1e-05 25.2 4.9 3.8e-05 23.5 4.9 2.0 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e RNA_pol_3_Rpc31 PF11705.8 EGR33299.1 - 0.37 11.0 5.1 0.52 10.5 5.1 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 MORN PF02493.20 EGR33300.1 - 1.3e-52 172.7 82.4 7e-09 35.1 1.8 10.6 11 0 0 11 11 11 9 MORN repeat DUF523 PF04463.12 EGR33300.1 - 1.5 8.9 5.1 6.6 6.8 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF523) Tudor_2 PF18104.1 EGR33300.1 - 3.6 7.3 21.0 11 5.8 0.1 6.4 6 0 0 6 6 6 0 Jumonji domain-containing protein 2A Tudor domain DUF953 PF06110.11 EGR33301.1 - 4e-19 68.4 0.0 4.7e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Rap1a PF18602.1 EGR33301.1 - 0.028 14.7 0.0 0.043 14.1 0.0 1.3 1 0 0 1 1 1 0 Rap1a immunity proteins PAS_9 PF13426.7 EGR33302.1 - 0.00017 21.8 0.2 0.00017 21.8 0.2 3.9 4 0 0 4 4 4 1 PAS domain PAS PF00989.25 EGR33302.1 - 0.0013 18.7 1.0 0.0052 16.8 0.0 2.6 2 0 0 2 2 2 1 PAS fold Ras PF00071.22 EGR33304.1 - 1.1e-43 148.7 1.8 1.3e-43 148.4 1.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR33304.1 - 7.9e-36 122.9 0.6 1.4e-35 122.1 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR33304.1 - 1.3e-17 63.8 2.0 1.6e-17 63.5 2.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGR33304.1 - 1.6e-08 34.2 1.2 2.6e-08 33.5 1.2 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGR33304.1 - 3.7e-07 30.2 0.1 6.2e-07 29.5 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGR33304.1 - 8.2e-06 25.5 0.1 0.00011 21.8 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGR33304.1 - 4.6e-05 22.9 0.5 6.9e-05 22.4 0.5 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EGR33304.1 - 0.00027 20.9 0.9 0.13 12.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EGR33304.1 - 0.003 17.6 2.8 0.051 13.6 2.8 2.7 1 1 0 1 1 1 1 Dynamin family TniB PF05621.11 EGR33304.1 - 0.014 14.8 0.7 0.073 12.5 0.0 2.2 3 0 0 3 3 3 0 Bacterial TniB protein TetR_C_16 PF17920.1 EGR33304.1 - 0.025 14.8 0.0 0.039 14.2 0.0 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain DNA_pol_E_B PF04042.16 EGR33304.1 - 0.099 12.0 0.1 0.14 11.5 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B Actin PF00022.19 EGR33305.1 - 1.8e-82 277.2 0.0 1.2e-81 274.5 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGR33305.1 - 0.0065 15.3 0.0 2.3 6.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EGR33305.1 - 0.025 15.0 0.0 0.065 13.7 0.0 1.8 1 1 0 1 1 1 0 Cell division protein FtsA Phage_RpbA PF10789.9 EGR33305.1 - 0.14 12.2 0.0 0.43 10.7 0.0 1.8 2 0 0 2 2 2 0 Phage RNA polymerase binding, RpbA RINGv PF12906.7 EGR33306.1 - 1.9e-08 34.3 10.7 4.6e-08 33.1 10.7 1.7 1 0 0 1 1 1 1 RING-variant domain FHA PF00498.26 EGR33306.1 - 3.8e-08 33.6 5.5 1.9e-07 31.3 0.4 2.9 3 1 0 3 3 3 1 FHA domain Yop-YscD_cpl PF16697.5 EGR33306.1 - 0.00041 20.6 0.1 0.0043 17.3 0.0 2.3 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain RNA_pol_Rpb1_7 PF04990.12 EGR33306.1 - 0.19 11.7 4.2 1.1 9.3 1.0 2.5 2 1 0 2 2 2 0 RNA polymerase Rpb1, domain 7 FANCL_C PF11793.8 EGR33306.1 - 0.82 9.9 8.7 1.7 8.9 8.1 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.6 EGR33306.1 - 0.91 9.9 10.3 2.8 8.4 10.3 1.9 1 1 0 1 1 1 0 Ring finger domain PHD PF00628.29 EGR33306.1 - 6 6.8 9.9 12 5.8 9.9 1.6 1 0 0 1 1 1 0 PHD-finger UCH PF00443.29 EGR33307.1 - 1e-44 153.0 16.5 1.6e-44 152.3 16.5 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR33307.1 - 1.4e-18 67.5 15.0 1.4e-18 67.5 15.0 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Cullin_Nedd8 PF10557.9 EGR33307.1 - 1.1 9.4 11.2 0.74 9.9 0.2 3.3 3 0 0 3 3 3 0 Cullin protein neddylation domain RRM_1 PF00076.22 EGR33308.1 - 1.8e-11 43.7 0.0 3.4e-11 42.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 EGR33308.1 - 7.6e-07 28.9 0.9 1.3e-06 28.2 0.9 1.4 1 0 0 1 1 1 1 Zinc knuckle RRM_3 PF08777.11 EGR33308.1 - 0.00052 20.0 0.1 0.0015 18.5 0.1 1.8 1 0 0 1 1 1 1 RNA binding motif zf-CCHC_5 PF14787.6 EGR33308.1 - 0.067 12.9 1.4 0.16 11.7 1.4 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RRM_5 PF13893.6 EGR33308.1 - 0.07 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_2 PF13696.6 EGR33308.1 - 0.15 11.9 0.2 0.28 11.1 0.2 1.4 1 0 0 1 1 1 0 Zinc knuckle Pkinase PF00069.25 EGR33309.1 - 3e-46 157.9 1.1 7.2e-46 156.7 1.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33309.1 - 5.2e-25 88.2 0.1 1.2e-24 87.0 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 EGR33309.1 - 0.059 13.0 0.2 0.059 13.0 0.2 3.0 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGR33309.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family PsbN PF02468.15 EGR33310.1 - 0.29 11.0 1.1 0.5 10.3 1.1 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre N protein (psbN) MORN PF02493.20 EGR33311.1 - 6.2e-50 164.2 74.7 6.8e-07 28.8 0.3 10.4 10 0 0 10 10 10 9 MORN repeat Guanylate_cyc PF00211.20 EGR33312.1 - 4.4e-14 52.5 0.0 1.2e-13 51.1 0.0 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain RPOL_N PF14700.6 EGR33312.1 - 1.9 7.8 22.9 0.014 14.8 7.1 2.4 2 0 0 2 2 2 0 DNA-directed RNA polymerase N-terminal PTPRCAP PF15713.5 EGR33312.1 - 7.2 6.9 11.5 18 5.6 11.5 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF2407_C PF13373.6 EGR33312.1 - 7.9 6.7 9.2 2.3 8.4 5.4 2.1 2 0 0 2 2 2 0 DUF2407 C-terminal domain Tctex-1 PF03645.13 EGR33313.1 - 1.5e-22 79.8 2.7 1.8e-22 79.5 2.7 1.1 1 0 0 1 1 1 1 Tctex-1 family Vps8 PF12816.7 EGR33313.1 - 0.027 14.0 0.6 0.039 13.5 0.6 1.5 1 1 0 1 1 1 0 Golgi CORVET complex core vacuolar protein 8 Ank_2 PF12796.7 EGR33314.1 - 4.9e-05 23.8 0.1 0.00011 22.7 0.1 1.5 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGR33314.1 - 0.0077 16.8 0.1 0.032 14.8 0.0 1.9 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGR33314.1 - 0.01 16.1 0.0 0.016 15.5 0.0 1.4 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR33314.1 - 0.024 15.2 0.0 0.31 11.7 0.0 2.6 2 1 1 3 3 3 0 Ankyrin repeat Ank PF00023.30 EGR33314.1 - 0.037 14.5 0.0 0.68 10.5 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeat PDEase_I PF00233.19 EGR33315.1 - 3.8e-66 223.2 9.7 5.5e-66 222.7 9.7 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Pkinase PF00069.25 EGR33315.1 - 6.1e-11 42.2 0.9 1.6e-10 40.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain HATPase_c PF02518.26 EGR33316.1 - 5.3e-20 72.0 0.2 9.7e-20 71.2 0.1 1.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGR33316.1 - 6.8e-06 26.0 0.2 0.00011 22.0 0.0 2.1 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase M60-like_N PF17291.2 EGR33316.1 - 0.021 14.7 0.2 0.036 13.9 0.2 1.4 1 0 0 1 1 1 0 N-terminal domain of M60-like peptidases HATPase_c_2 PF13581.6 EGR33316.1 - 0.061 13.3 0.0 0.094 12.7 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain SirA PF10747.9 EGR33316.1 - 0.07 13.5 8.9 0.19 12.1 8.8 1.7 1 1 0 1 1 1 0 Sporulation inhibitor of replication protein SirA Band_3_cyto PF07565.13 EGR33316.1 - 0.13 12.1 0.4 0.16 11.7 0.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CDP-OH_P_transf PF01066.21 EGR33317.1 - 5.5e-18 65.5 0.2 1e-17 64.7 0.2 1.4 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase PHD PF00628.29 EGR33318.1 - 4.4e-10 39.3 12.9 4.4e-10 39.3 12.9 2.2 1 1 1 2 2 2 1 PHD-finger zf-PHD-like PF15446.6 EGR33318.1 - 0.0034 17.0 7.2 0.0034 17.0 7.2 1.7 1 1 1 2 2 2 1 PHD/FYVE-zinc-finger like domain YL1 PF05764.13 EGR33318.1 - 0.018 15.1 13.2 0.019 15.1 13.2 1.1 1 0 0 1 1 1 0 YL1 nuclear protein PHD_2 PF13831.6 EGR33318.1 - 0.87 9.2 11.1 0.26 10.8 7.3 2.2 1 1 0 1 1 1 0 PHD-finger SDA1 PF05285.12 EGR33318.1 - 1.1 8.6 18.8 1.1 8.6 18.8 1.0 1 0 0 1 1 1 0 SDA1 SMN PF06003.12 EGR33318.1 - 1.8 7.8 7.0 2.2 7.5 7.0 1.1 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) MGC-24 PF05283.11 EGR33318.1 - 2.8 8.4 10.6 3.9 7.9 10.6 1.4 1 1 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Merozoite_SPAM PF07133.11 EGR33318.1 - 4.5 7.2 28.6 5.2 7.0 28.6 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Radial_spoke PF04712.12 EGR33318.1 - 4.9 6.0 10.8 4.6 6.1 10.8 1.1 1 0 0 1 1 1 0 Radial spokehead-like protein Nop14 PF04147.12 EGR33318.1 - 5.6 5.0 20.1 6 5.0 20.1 1.0 1 0 0 1 1 1 0 Nop14-like family Mpp10 PF04006.12 EGR33318.1 - 7.2 4.9 19.3 7.7 4.8 19.3 1.0 1 0 0 1 1 1 0 Mpp10 protein HA2 PF04408.23 EGR33320.1 - 1.9e-16 60.2 0.1 5.7e-16 58.8 0.0 1.8 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGR33320.1 - 9.1e-16 58.2 7.4 4.4e-15 56.0 0.0 4.0 2 2 1 3 3 3 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EGR33320.1 - 1.4e-10 41.4 0.1 5.1e-10 39.6 0.1 2.0 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EGR33320.1 - 6.9e-10 39.0 3.0 2.9e-09 36.9 3.0 2.1 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGR33320.1 - 1.8e-06 28.3 0.7 1.5e-05 25.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 EGR33320.1 - 3.5e-05 24.2 0.2 7.7e-05 23.1 0.2 1.6 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EGR33320.1 - 0.00013 22.0 2.9 0.00013 22.0 2.9 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Flavi_DEAD PF07652.14 EGR33320.1 - 0.00026 21.0 0.8 0.0019 18.2 0.2 2.6 3 0 0 3 3 3 1 Flavivirus DEAD domain DUF2075 PF09848.9 EGR33320.1 - 0.0028 16.9 0.1 0.0064 15.8 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) T2SSE PF00437.20 EGR33320.1 - 0.0042 16.2 0.1 0.012 14.7 0.1 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 EGR33320.1 - 0.0046 16.3 0.0 0.014 14.8 0.0 1.8 1 0 0 1 1 1 1 KaiC AAA_30 PF13604.6 EGR33320.1 - 0.0046 16.7 0.0 0.0084 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 EGR33320.1 - 0.011 15.5 0.1 0.047 13.5 0.1 2.1 1 0 0 1 1 1 0 Helicase RsgA_GTPase PF03193.16 EGR33320.1 - 0.027 14.4 0.1 0.13 12.1 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase PhoH PF02562.16 EGR33320.1 - 0.028 13.9 3.0 0.082 12.4 1.6 2.6 2 1 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 EGR33320.1 - 0.03 14.8 0.7 0.03 14.8 0.7 2.8 2 1 0 2 2 2 0 ABC transporter Zeta_toxin PF06414.12 EGR33320.1 - 0.11 11.8 0.4 0.41 9.9 0.1 2.1 1 1 1 2 2 2 0 Zeta toxin AAA_23 PF13476.6 EGR33320.1 - 0.14 12.6 0.1 0.14 12.6 0.1 3.5 3 2 0 3 3 3 0 AAA domain DUF3902 PF13042.6 EGR33320.1 - 1.3 8.6 5.3 2.3 7.8 0.6 3.4 5 0 0 5 5 5 0 Protein of unknown function (DUF3902) AAA_11 PF13086.6 EGR33320.1 - 1.4 8.6 11.0 0.42 10.3 0.4 3.3 2 2 0 3 3 3 0 AAA domain Citrate_synt PF00285.21 EGR33321.1 - 8.7e-99 331.0 0.0 1e-98 330.7 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Mst1_SARAH PF11629.8 EGR33321.1 - 0.035 14.2 0.2 0.079 13.1 0.2 1.5 1 0 0 1 1 1 0 C terminal SARAH domain of Mst1 DUF2778 PF10908.8 EGR33321.1 - 0.083 13.2 0.0 0.59 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2778) PP2C PF00481.21 EGR33322.1 - 5.1e-53 180.3 0.2 5.6e-53 180.2 0.2 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGR33322.1 - 0.00044 20.2 0.3 0.37 10.7 0.1 2.0 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 EGR33322.1 - 0.0044 16.7 0.0 0.015 14.9 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C E1-E2_ATPase PF00122.20 EGR33323.1 - 1.6e-40 138.5 3.1 1.6e-40 138.5 3.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGR33323.1 - 2.8e-39 134.7 11.0 2.8e-39 134.7 11.0 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGR33323.1 - 1.5e-22 79.5 0.0 3.8e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) RCC1 PF00415.18 EGR33323.1 - 1.3e-15 57.7 0.6 1.5e-09 38.3 0.0 4.0 4 0 0 4 4 4 2 Regulator of chromosome condensation (RCC1) repeat Hydrolase PF00702.26 EGR33323.1 - 2.1e-11 44.5 0.3 1.8e-09 38.2 0.3 2.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGR33323.1 - 5.1e-10 38.9 0.0 2.3e-09 36.8 0.0 2.2 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus RCC1_2 PF13540.6 EGR33323.1 - 2e-09 37.0 1.7 4.3e-05 23.2 0.0 3.7 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat Herpes_UL4 PF03277.13 EGR33323.1 - 0.093 12.4 0.0 0.2 11.3 0.0 1.5 1 0 0 1 1 1 0 Herpesvirus UL4 family Methyltransf_11 PF08241.12 EGR33324.1 - 1e-13 51.7 0.0 2.4e-13 50.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGR33324.1 - 1.4e-12 48.1 0.0 3.8e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGR33324.1 - 6.1e-09 35.8 0.0 6.1e-09 35.8 0.0 2.8 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGR33324.1 - 1.2e-07 31.7 0.0 2.5e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGR33324.1 - 1.8e-06 28.6 0.1 1.8e-06 28.6 0.1 2.8 3 1 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGR33324.1 - 0.00019 20.9 0.0 0.00055 19.3 0.0 1.8 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 EGR33324.1 - 0.01 15.5 0.0 0.03 13.9 0.0 1.9 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW 2OG-FeII_Oxy_2 PF13532.6 EGR33324.1 - 0.022 14.9 0.0 0.056 13.6 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily UCH PF00443.29 EGR33325.1 - 2.6e-07 30.4 0.3 2.6e-07 30.4 0.3 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-MYND PF01753.18 EGR33325.1 - 0.00076 19.5 12.3 0.0015 18.6 12.3 1.5 1 0 0 1 1 1 1 MYND finger Lar_restr_allev PF14354.6 EGR33325.1 - 0.27 11.6 6.0 0.66 10.4 6.0 1.6 1 0 0 1 1 1 0 Restriction alleviation protein Lar Peptidase_C12 PF01088.21 EGR33326.1 - 2.4e-43 148.4 0.5 3.1e-43 148.0 0.5 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 tRNA-synt_1 PF00133.22 EGR33327.1 - 1.1e-226 753.8 0.6 2.1e-226 752.9 0.6 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGR33327.1 - 2.5e-22 79.5 1.2 2.5e-22 79.5 1.2 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGR33327.1 - 2.3e-12 46.4 7.6 9e-05 21.4 0.0 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) DUF3986 PF13143.6 EGR33327.1 - 0.008 17.1 3.1 0.35 11.9 0.5 3.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3986) RhoGAP-FF1 PF16512.5 EGR33327.1 - 0.23 12.1 3.4 0.82 10.4 0.2 3.3 3 0 0 3 3 3 0 p190-A and -B Rho GAPs FF domain Caudo_TAP PF02413.17 EGR33327.1 - 1.7 8.8 6.5 0.3 11.2 1.4 2.3 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK Pkinase PF00069.25 EGR33328.1 - 1.3e-59 201.7 17.3 1e-41 143.0 3.7 3.2 3 1 1 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33328.1 - 6.8e-39 133.7 0.8 3.6e-38 131.3 0.8 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EGR33328.1 - 1.4e-11 44.7 3.1 1.8e-05 25.1 0.1 3.2 3 0 0 3 3 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR33328.1 - 1.5e-07 30.7 2.2 0.0022 17.8 0.1 4.1 3 0 0 3 3 3 2 EF-hand domain Kinase-like PF14531.6 EGR33328.1 - 4.6e-06 26.1 5.2 0.00068 19.0 0.0 2.9 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.14 EGR33328.1 - 8.7e-06 25.2 3.6 0.019 14.4 0.3 2.5 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR33328.1 - 0.0002 20.3 0.1 0.0002 20.3 0.1 1.8 2 0 0 2 2 2 1 Fungal protein kinase EF-hand_1 PF00036.32 EGR33328.1 - 0.00042 19.7 6.9 0.0013 18.2 0.5 4.2 4 0 0 4 4 4 1 EF hand EF-hand_8 PF13833.6 EGR33328.1 - 0.0043 16.9 1.2 1 9.2 0.1 3.3 2 1 2 4 4 4 2 EF-hand domain pair EFhand_Ca_insen PF08726.10 EGR33328.1 - 0.06 13.4 0.4 1.3 9.1 0.0 2.7 2 0 0 2 2 2 0 Ca2+ insensitive EF hand APH PF01636.23 EGR33328.1 - 0.068 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2122 PF09895.9 EGR33328.1 - 0.088 13.2 0.2 0.27 11.6 0.2 1.9 1 0 0 1 1 1 0 RecB-family nuclease (DUF2122) EF-hand_4 PF12763.7 EGR33328.1 - 0.11 12.4 2.6 1.1 9.3 0.5 2.8 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF1840 PF08895.11 EGR33328.1 - 9 6.7 8.7 1.5 9.2 2.3 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF1840) Ribosomal_L24e PF01246.20 EGR33329.1 - 2.4e-21 75.7 2.5 2.4e-21 75.7 2.5 2.4 2 0 0 2 2 2 1 Ribosomal protein L24e SICA_C PF12879.7 EGR33329.1 - 0.017 15.1 1.8 0.026 14.5 1.2 1.4 1 1 0 1 1 1 0 SICA C-terminal inner membrane domain DUF775 PF05603.12 EGR33329.1 - 0.035 13.7 1.7 0.042 13.4 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF775) UPF0767 PF15990.5 EGR33329.1 - 0.43 10.8 4.9 0.42 10.8 3.4 1.9 1 1 0 1 1 1 0 UPF0767 family Metallophos PF00149.28 EGR33330.1 - 6.4e-23 82.3 0.4 1.1e-22 81.6 0.4 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase RRM_1 PF00076.22 EGR33330.1 - 8.1e-19 67.2 0.0 1.7e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGR33330.1 - 5.6e-05 22.7 0.0 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGR33330.1 - 0.0014 18.7 0.0 0.0026 17.7 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif Pkinase PF00069.25 EGR33331.1 - 1.9e-26 93.0 0.1 4.3e-26 91.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain EF-hand_7 PF13499.6 EGR33331.1 - 1.7e-15 57.2 7.1 2.7e-09 37.3 0.2 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGR33331.1 - 1.4e-12 46.4 6.2 5.8e-05 22.4 0.2 4.5 4 0 0 4 4 4 2 EF hand EF-hand_1 PF00036.32 EGR33331.1 - 1.6e-12 46.0 5.2 7.4e-05 22.0 0.1 4.3 4 0 0 4 4 4 2 EF hand EF-hand_6 PF13405.6 EGR33331.1 - 9e-11 40.8 2.9 0.00093 18.9 0.1 4.1 3 1 0 3 3 3 2 EF-hand domain Pkinase_Tyr PF07714.17 EGR33331.1 - 1.8e-08 34.0 0.0 3.1e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_8 PF13833.6 EGR33331.1 - 6e-05 22.8 0.8 0.085 12.7 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGR33331.1 - 0.0016 18.7 0.8 0.0038 17.5 0.8 1.7 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region MecA_N PF05223.11 EGR33331.1 - 0.0091 16.3 1.4 0.026 14.8 1.4 1.8 1 0 0 1 1 1 1 NTF2-like N-terminal transpeptidase domain DUF4994 PF16385.5 EGR33331.1 - 0.026 14.4 0.2 0.71 9.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function Fibrillarin PF01269.17 EGR33332.1 - 9.8e-51 172.0 0.1 1.2e-50 171.7 0.1 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 EGR33332.1 - 0.00081 19.1 0.0 0.001 18.8 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EGR33332.1 - 0.0062 16.3 0.0 0.0078 16.0 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 EGR33332.1 - 0.039 13.6 0.0 0.3 10.7 0.0 1.9 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F DUF2732 PF10809.8 EGR33333.1 - 0.084 12.7 0.3 0.084 12.7 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2732) PKD_3 PF16820.5 EGR33333.1 - 0.7 9.7 4.6 6.4 6.6 0.1 4.2 5 0 0 5 5 5 0 PKD-like domain EF-hand_7 PF13499.6 EGR33335.1 - 1.7e-15 57.2 0.8 6.4e-07 29.7 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR33335.1 - 1.2e-12 46.4 2.9 4.5e-06 25.8 0.1 4.4 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGR33335.1 - 2.6e-12 45.6 2.0 0.00032 20.4 0.1 4.3 3 2 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 EGR33335.1 - 1.2e-09 37.9 0.1 0.00088 19.1 0.1 2.8 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGR33335.1 - 2.6e-05 23.5 6.3 0.00076 18.9 0.0 4.0 4 2 1 5 5 5 2 EF hand EF-hand_9 PF14658.6 EGR33335.1 - 0.0012 19.1 0.1 1.4 9.3 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain DUF2167 PF09935.9 EGR33335.1 - 0.033 13.4 0.2 0.052 12.7 0.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2167) IU_nuc_hydro PF01156.19 EGR33335.1 - 0.14 11.7 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Inosine-uridine preferring nucleoside hydrolase Activator_LAG-3 PF11498.8 EGR33336.1 - 1.6 7.6 8.0 1.7 7.5 8.0 1.0 1 0 0 1 1 1 0 Transcriptional activator LAG-3 WD40 PF00400.32 EGR33337.1 - 2.4e-09 37.6 2.6 3.3e-06 27.7 1.1 2.4 2 1 0 2 2 2 2 WD domain, G-beta repeat RHD_dimer PF16179.5 EGR33337.1 - 0.0052 16.8 0.8 0.0089 16.0 0.4 1.6 1 1 0 1 1 1 1 Rel homology dimerisation domain ANAPC4_WD40 PF12894.7 EGR33337.1 - 0.0053 17.0 0.3 0.018 15.3 0.2 1.9 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain DUF3786 PF12654.7 EGR33338.1 - 0.016 14.8 1.6 0.018 14.7 1.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3786) PepSY_TM_like_2 PF16357.5 EGR33338.1 - 1.1 9.2 4.1 1.3 9.0 4.1 1.1 1 0 0 1 1 1 0 Putative PepSY_TM-like Yip1 PF04893.17 EGR33339.1 - 2.3e-06 27.5 13.9 2.3e-06 27.5 13.9 1.3 1 1 0 1 1 1 1 Yip1 domain LRR_6 PF13516.6 EGR33340.1 - 6.5e-09 35.1 11.7 0.00026 20.8 0.1 5.2 4 0 0 4 4 4 4 Leucine Rich repeat CRAL_TRIO PF00650.20 EGR33341.1 - 2.1e-18 66.6 3.9 2.1e-18 66.6 3.9 1.8 2 0 0 2 2 2 1 CRAL/TRIO domain RBD-FIP PF09457.10 EGR33341.1 - 0.032 14.1 2.3 0.34 10.9 0.2 3.1 2 0 0 2 2 2 0 FIP domain Pkinase PF00069.25 EGR33342.1 - 3.9e-58 196.9 3.3 5.4e-58 196.4 3.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33342.1 - 1.1e-37 129.7 0.5 1.3e-37 129.5 0.5 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR33342.1 - 2.6e-08 33.1 0.0 5.6e-07 28.7 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGR33342.1 - 7.2e-08 32.1 1.6 1.1e-06 28.2 1.6 2.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR33342.1 - 0.0017 17.8 0.3 0.0023 17.3 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGR33342.1 - 0.0023 17.6 2.8 0.029 14.0 0.5 2.2 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGR33342.1 - 0.0052 16.7 0.0 2.3 8.1 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family DUF1910 PF08928.10 EGR33342.1 - 0.0069 16.4 3.1 0.013 15.5 3.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1910) Pkinase PF00069.25 EGR33343.1 - 9.3e-62 208.8 0.0 9.3e-62 208.8 0.0 3.7 3 2 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33343.1 - 2.3e-32 112.3 0.0 2.3e-32 112.3 0.0 2.5 2 1 0 2 2 2 1 Protein tyrosine kinase Ank_2 PF12796.7 EGR33343.1 - 8.1e-20 71.2 4.8 1.1e-14 54.8 0.4 3.2 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGR33343.1 - 1.9e-17 63.3 0.4 1.7e-09 38.0 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGR33343.1 - 1.8e-14 53.4 5.8 0.00059 20.2 0.1 4.0 3 1 1 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EGR33343.1 - 1.3e-12 47.6 0.4 4.4e-06 26.9 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR33343.1 - 1.4e-10 40.5 0.5 0.038 14.5 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat Ion_trans PF00520.31 EGR33344.1 - 2.5e-142 472.3 115.7 3.5e-51 173.8 37.7 4.4 5 0 0 5 5 5 3 Ion transport protein PKD_channel PF08016.12 EGR33344.1 - 2.9e-06 26.2 97.7 0.0014 17.4 12.9 8.2 6 3 3 9 9 9 7 Polycystin cation channel TPR_12 PF13424.6 EGR33345.1 - 2.6e-10 40.4 0.4 2.6e-10 40.4 0.4 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGR33345.1 - 1.1e-06 28.3 1.8 0.02 15.0 0.6 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGR33345.1 - 0.00012 21.8 5.2 0.00027 20.6 0.4 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat ObR_Ig PF18589.1 EGR33345.1 - 0.00036 20.9 0.2 0.064 13.6 0.0 2.4 2 0 0 2 2 2 1 Obesity receptor immunoglobulin like domain TPR_8 PF13181.6 EGR33345.1 - 0.018 15.2 2.3 9.2 6.8 0.1 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGR33345.1 - 0.095 12.6 2.4 0.62 10.0 0.2 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat PAS_9 PF13426.7 EGR33346.1 - 0.003 17.8 6.7 0.11 12.8 0.0 4.0 3 0 0 3 3 3 2 PAS domain PAS PF00989.25 EGR33346.1 - 0.2 11.6 0.0 0.2 11.6 0.0 3.3 4 0 0 4 4 4 0 PAS fold TerY_C PF15616.6 EGR33346.1 - 1.8 8.6 6.6 2.1 8.4 2.4 2.7 2 0 0 2 2 2 0 TerY-C metal binding domain Indigoidine_A PF04227.12 EGR33347.1 - 6.9e-126 419.5 0.4 7.8e-126 419.3 0.4 1.0 1 0 0 1 1 1 1 Indigoidine synthase A like protein CTP_transf_1 PF01148.20 EGR33348.1 - 7.6e-30 104.6 7.0 1e-29 104.2 7.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family DUF2207 PF09972.9 EGR33348.1 - 4.3 6.0 13.8 1.1 8.0 1.9 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF202 PF02656.15 EGR33348.1 - 8.2 7.0 6.4 0.97 9.9 0.9 2.3 2 2 0 2 2 2 0 Domain of unknown function (DUF202) zf-SAP30 PF13866.6 EGR33349.1 - 0.091 12.9 0.1 0.17 12.0 0.1 1.3 1 0 0 1 1 1 0 SAP30 zinc-finger SecE PF00584.20 EGR33350.1 - 3.7e-14 52.4 0.0 4.3e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex Tetraspanin PF00335.20 EGR33351.1 - 3.8e-13 49.7 13.6 2.9e-12 46.8 13.6 2.0 1 1 0 1 1 1 1 Tetraspanin family RseC_MucC PF04246.12 EGR33351.1 - 0.099 12.6 2.4 0.18 11.8 0.5 2.0 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Imm9 PF15587.6 EGR33351.1 - 2.3 7.9 12.3 0.24 11.1 2.1 2.9 3 0 0 3 3 3 0 Immunity protein 9 DUF4820 PF16091.5 EGR33352.1 - 0.0061 16.0 2.7 0.0061 16.0 2.7 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4820) MutS_III PF05192.18 EGR33352.1 - 0.12 12.6 9.9 18 5.5 0.0 2.5 2 1 1 3 3 3 0 MutS domain III DUF3314 PF11771.8 EGR33352.1 - 0.16 12.1 5.9 0.31 11.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3314) Eapp_C PF10238.9 EGR33352.1 - 1.6 8.8 8.3 0.46 10.5 0.9 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF3984 PF13136.6 EGR33352.1 - 7 6.0 6.3 11 5.3 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) DUF2457 PF10446.9 EGR33352.1 - 8 5.5 14.7 11 5.0 14.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CobT PF06213.12 EGR33352.1 - 9.9 5.5 11.5 17 4.7 11.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Mito_carr PF00153.27 EGR33353.1 - 2.3e-44 149.3 3.3 3.6e-21 74.9 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGR33353.1 - 0.0013 18.0 0.4 0.05 12.8 0.1 2.2 2 0 0 2 2 2 2 Gammaproteobacterial serine protease DUF5359 PF17313.2 EGR33353.1 - 0.029 14.4 0.9 0.8 9.7 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5359) DUF2109 PF09882.9 EGR33353.1 - 0.088 12.8 0.2 4.9 7.2 0.0 2.4 2 0 0 2 2 2 0 Predicted membrane protein (DUF2109) SET PF00856.28 EGR33354.1 - 0.01 16.2 0.0 0.016 15.6 0.0 1.3 1 0 0 1 1 1 0 SET domain CD20 PF04103.15 EGR33355.1 - 0.25 11.4 3.1 1.3 9.1 0.8 2.1 1 1 1 2 2 2 0 CD20-like family DUF1493 PF07377.12 EGR33356.1 - 4.2 7.9 6.4 1.5 9.3 0.8 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF1493) PAS PF00989.25 EGR33357.1 - 0.00028 20.8 0.0 0.00065 19.7 0.0 1.5 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EGR33357.1 - 0.0015 18.7 0.2 0.0032 17.7 0.2 1.6 1 1 0 1 1 1 1 PAS domain PAS_4 PF08448.10 EGR33357.1 - 0.0027 17.9 0.0 0.0049 17.1 0.0 1.4 1 0 0 1 1 1 1 PAS fold Imm6 PF14434.6 EGR33357.1 - 0.024 14.5 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 Immunity protein Imm6 FancD2 PF14631.6 EGR33358.1 - 0.00049 17.7 0.1 0.00049 17.7 0.1 1.0 1 0 0 1 1 1 1 Fanconi anaemia protein FancD2 nuclease Aha1_N PF09229.11 EGR33359.1 - 2.3e-23 82.9 2.9 3.5e-23 82.3 2.9 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal SprA-related PF12118.8 EGR33359.1 - 0.029 13.5 5.3 0.044 12.9 5.3 1.3 1 0 0 1 1 1 0 SprA-related family FAD_binding_1 PF00667.20 EGR33359.1 - 0.067 12.7 1.4 0.082 12.5 1.4 1.2 1 0 0 1 1 1 0 FAD binding domain Muted PF14942.6 EGR33359.1 - 0.093 13.1 11.8 0.17 12.2 11.8 1.4 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein KTI12 PF08433.10 EGR33360.1 - 1.3e-56 192.1 2.0 1.5e-56 191.9 2.0 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EGR33360.1 - 1.4e-10 41.5 0.0 2.1e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGR33360.1 - 6.3e-07 30.0 0.3 1.1e-06 29.3 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGR33360.1 - 5.3e-06 26.8 0.1 1.3e-05 25.5 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 EGR33360.1 - 0.00019 21.8 0.3 0.00089 19.7 0.1 2.1 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGR33360.1 - 0.00075 19.5 0.7 0.0013 18.7 0.5 1.5 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGR33360.1 - 0.0012 18.6 0.0 0.0019 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EGR33360.1 - 0.0039 17.6 0.1 0.0066 16.9 0.1 1.7 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.20 EGR33360.1 - 0.004 17.1 0.0 0.0058 16.5 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase Viral_helicase1 PF01443.18 EGR33360.1 - 0.0049 16.7 0.1 0.0057 16.4 0.1 1.5 1 1 0 1 1 1 1 Viral (Superfamily 1) RNA helicase Zeta_toxin PF06414.12 EGR33360.1 - 0.0054 16.0 0.0 0.014 14.7 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.14 EGR33360.1 - 0.0079 16.2 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EGR33360.1 - 0.011 16.1 0.7 0.096 13.1 0.1 2.4 1 1 1 2 2 2 0 RNA helicase SRP54 PF00448.22 EGR33360.1 - 0.012 15.2 0.1 0.071 12.7 0.0 2.2 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain NTPase_1 PF03266.15 EGR33360.1 - 0.016 15.1 0.0 0.029 14.3 0.0 1.5 1 0 0 1 1 1 0 NTPase ATP_bind_1 PF03029.17 EGR33360.1 - 0.051 13.4 0.0 0.15 11.8 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PRK PF00485.18 EGR33360.1 - 0.057 13.2 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NACHT PF05729.12 EGR33360.1 - 0.058 13.3 0.4 0.34 10.8 0.1 2.4 2 1 0 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 EGR33360.1 - 0.063 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 EGR33360.1 - 0.075 12.7 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGR33360.1 - 0.08 13.3 0.3 0.46 10.8 0.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGR33360.1 - 0.13 12.5 0.1 0.29 11.4 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGR33360.1 - 0.18 12.1 0.0 0.32 11.4 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain DNA_ligase_OB_2 PF14743.6 EGR33361.1 - 4.4e-30 103.5 0.2 1.1e-29 102.2 0.2 1.8 1 0 0 1 1 1 1 DNA ligase OB-like domain DNA_ligase_A_M PF01068.21 EGR33361.1 - 5.8e-16 58.8 0.0 2.1e-15 56.9 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase domain UvrA_inter PF17760.1 EGR33361.1 - 0.089 12.9 12.9 0.054 13.6 2.5 3.4 3 0 0 3 3 3 0 UvrA interaction domain MIR PF02815.19 EGR33362.1 - 0.0035 17.2 5.1 0.091 12.6 0.7 2.6 2 0 0 2 2 2 2 MIR domain DUF4484 PF14831.6 EGR33362.1 - 2.5 8.1 5.9 0.38 10.8 0.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) RIH_assoc PF08454.11 EGR33363.1 - 3.4e-13 49.3 13.3 3.4e-13 49.3 13.3 9.2 6 2 1 7 7 7 1 RyR and IP3R Homology associated Ion_trans PF00520.31 EGR33363.1 - 5.8e-07 29.0 28.7 5.8e-07 29.0 28.7 3.9 2 2 0 2 2 2 1 Ion transport protein Gemini_AL1 PF00799.20 EGR33364.1 - 0.11 12.9 1.8 0.13 12.6 1.8 1.2 1 0 0 1 1 1 0 Geminivirus Rep catalytic domain Peptidase_M49 PF03571.15 EGR33365.1 - 1.5e-195 650.8 4.7 2.1e-195 650.3 4.7 1.2 1 0 0 1 1 1 1 Peptidase family M49 DUF1700 PF08006.11 EGR33365.1 - 0.042 13.4 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) Cullin_binding PF03556.15 EGR33365.1 - 1.6 9.2 6.6 0.28 11.6 0.8 2.8 4 0 0 4 4 4 0 Cullin binding Cpn60_TCP1 PF00118.24 EGR33366.1 - 4e-167 556.8 5.1 4.5e-167 556.6 5.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family BNIP2 PF12496.8 EGR33367.1 - 0.14 12.6 1.8 0.16 12.4 1.8 1.1 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 SF1-HH PF16275.5 EGR33369.1 - 3.3e-30 104.7 0.8 3.3e-30 104.7 0.8 2.8 3 0 0 3 3 3 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 EGR33369.1 - 1.2e-08 34.6 0.3 2.6e-08 33.6 0.3 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC_3 PF13917.6 EGR33369.1 - 0.0002 21.3 10.3 0.013 15.5 0.4 2.7 1 1 1 2 2 2 2 Zinc knuckle zf-CCHC PF00098.23 EGR33369.1 - 0.012 15.7 6.8 0.1 12.7 0.3 2.4 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_4 PF14392.6 EGR33369.1 - 0.32 10.8 4.5 1.7 8.5 0.2 2.6 2 0 0 2 2 2 0 Zinc knuckle Mu-like_Com PF10122.9 EGR33369.1 - 0.5 9.9 2.8 1.3 8.5 2.8 1.7 1 1 0 1 1 1 0 Mu-like prophage protein Com zf-CCHC_5 PF14787.6 EGR33369.1 - 1.1 9.0 8.3 1.6 8.5 1.8 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DnaJ_CXXCXGXG PF00684.19 EGR33369.1 - 1.2 9.6 6.3 0.44 10.9 3.0 2.0 2 0 0 2 2 2 0 DnaJ central domain zinc-ribbons_6 PF07191.12 EGR33369.1 - 1.8 8.6 6.6 2.1 8.4 0.5 2.4 1 1 1 2 2 2 0 zinc-ribbons Ion_trans_2 PF07885.16 EGR33370.1 - 1.5e-11 44.1 2.8 3.2e-11 43.0 2.8 1.6 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 EGR33370.1 - 2e-11 43.8 0.0 3.4e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 EGR33370.1 - 2.6e-09 36.7 6.4 5.8e-09 35.6 6.4 1.6 1 0 0 1 1 1 1 Ion transport protein SR-25 PF10500.9 EGR33370.1 - 0.099 12.2 12.5 0.2 11.2 12.5 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF3464 PF11947.8 EGR33370.1 - 0.67 9.7 4.9 16 5.2 0.0 2.6 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 DUF4604 PF15377.6 EGR33370.1 - 0.91 9.9 14.6 1.6 9.1 14.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4604) zf-CCHC_4 PF14392.6 EGR33370.1 - 3 7.6 6.4 3.4 7.5 3.9 2.4 2 0 0 2 2 2 0 Zinc knuckle Cation_ATPase_C PF00689.21 EGR33372.1 - 6.3e-41 140.1 4.9 6.3e-41 140.1 4.9 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGR33372.1 - 1e-36 126.2 5.2 3.9e-36 124.3 0.8 2.6 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGR33372.1 - 6.7e-19 67.8 0.0 2.1e-18 66.2 0.0 1.9 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGR33372.1 - 2.9e-16 60.4 2.0 6.7e-10 39.6 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGR33372.1 - 1.1e-07 31.4 0.0 4.6e-07 29.4 0.0 2.1 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGR33372.1 - 0.0013 18.5 0.3 0.0013 18.5 0.3 3.3 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase NiFe_hyd_3_EhaA PF17367.2 EGR33372.1 - 0.7 10.1 6.2 0.19 11.9 0.5 2.6 2 0 0 2 2 2 0 NiFe-hydrogenase-type-3 Eha complex subunit A Pkinase PF00069.25 EGR33373.1 - 6.3e-60 202.8 0.1 7.2e-60 202.6 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33373.1 - 2.5e-35 122.0 0.0 2.9e-35 121.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33373.1 - 3.8e-06 26.4 0.0 1.2e-05 24.8 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR33373.1 - 0.085 11.6 0.0 0.088 11.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Aldo_ket_red PF00248.21 EGR33374.1 - 5.4e-44 150.6 0.5 1.6e-41 142.4 0.5 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family WD40 PF00400.32 EGR33375.1 - 0.0034 18.2 12.1 0.42 11.6 0.3 5.5 5 1 0 5 5 5 3 WD domain, G-beta repeat B PF02216.16 EGR33376.1 - 4.1e-06 26.7 0.1 8.1e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 B domain CLIP PF12032.8 EGR33376.1 - 0.032 14.5 1.5 0.07 13.4 0.4 2.1 2 0 0 2 2 2 0 Regulatory CLIP domain of proteinases NIF PF03031.18 EGR33377.1 - 6.4e-37 126.7 7.4 6.4e-37 126.7 7.4 1.4 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase RRM_1 PF00076.22 EGR33379.1 - 4.9e-14 51.9 0.1 1.2e-13 50.6 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGR33379.1 - 6.5e-05 22.5 0.2 0.0001 21.9 0.2 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGR33379.1 - 0.0039 17.2 0.2 0.018 15.1 0.2 2.2 1 0 0 1 1 1 1 RNA binding motif SpuA_C PF18033.1 EGR33379.1 - 0.013 15.6 0.1 0.027 14.5 0.1 1.6 1 0 0 1 1 1 0 SpuA C-terminal RRM_occluded PF16842.5 EGR33379.1 - 0.03 14.2 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif Calici_coat_C PF08435.11 EGR33379.1 - 0.059 12.9 0.1 0.059 12.9 0.1 1.5 2 0 0 2 2 2 0 Calicivirus coat protein C-terminal TPR_2 PF07719.17 EGR33380.1 - 1.4e-29 99.8 12.0 0.044 13.9 0.2 10.9 11 0 0 11 11 10 8 Tetratricopeptide repeat TPR_1 PF00515.28 EGR33380.1 - 3.6e-23 80.4 24.3 0.00035 20.3 0.0 11.0 11 0 0 11 11 11 6 Tetratricopeptide repeat MORN PF02493.20 EGR33380.1 - 5e-17 60.7 23.8 5e-06 26.1 0.5 5.7 5 0 0 5 5 5 5 MORN repeat TPR_8 PF13181.6 EGR33380.1 - 5.9e-17 60.4 16.0 0.016 15.4 0.0 10.4 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGR33380.1 - 1.3e-16 60.6 7.1 2.2e-05 24.6 0.0 7.7 6 2 2 8 8 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 EGR33380.1 - 5.7e-12 44.8 2.3 0.072 13.2 0.0 6.5 6 1 1 7 7 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGR33380.1 - 9.3e-12 44.8 13.1 0.19 12.4 0.4 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGR33380.1 - 4.3e-11 42.3 11.6 0.046 13.4 0.0 7.4 6 2 2 8 8 8 4 TPR repeat ANAPC3 PF12895.7 EGR33380.1 - 5.2e-11 42.6 14.6 3.3e-05 24.0 1.7 5.4 5 2 2 7 7 5 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGR33380.1 - 6.2e-11 42.6 5.3 1.5 9.4 1.1 6.9 6 2 2 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGR33380.1 - 2.7e-08 34.0 0.0 2.6 9.1 0.0 6.5 4 1 2 6 6 6 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGR33380.1 - 1.1e-07 32.3 0.1 1.1 9.9 0.0 6.0 5 2 2 7 7 6 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGR33380.1 - 0.00063 19.0 0.9 0.036 13.3 0.1 2.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGR33380.1 - 0.0017 17.8 1.5 0.74 9.1 0.0 4.0 3 2 1 5 5 5 1 MalT-like TPR region DUF3048_C PF17479.2 EGR33380.1 - 0.0027 18.1 5.1 0.7 10.3 0.4 3.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3048) C-terminal domain TPR_17 PF13431.6 EGR33380.1 - 0.0028 17.9 7.8 85 3.9 0.2 7.5 9 0 0 9 9 8 0 Tetratricopeptide repeat DUF2225 PF09986.9 EGR33380.1 - 0.015 15.1 1.1 0.015 15.1 1.1 4.4 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) ATP13 PF12921.7 EGR33380.1 - 0.015 15.1 0.9 0.17 11.7 0.0 3.1 3 2 1 4 4 4 0 Mitochondrial ATPase expression TPR_10 PF13374.6 EGR33380.1 - 0.026 14.4 8.9 8.2 6.5 0.0 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat RPN7 PF10602.9 EGR33380.1 - 0.03 14.0 4.6 2.1 8.0 0.2 4.4 2 1 2 4 4 4 0 26S proteasome subunit RPN7 BetaGal_dom4_5 PF13364.6 EGR33380.1 - 0.037 14.6 1.5 0.098 13.2 0.1 2.3 2 0 0 2 2 2 0 Beta-galactosidase jelly roll domain Fis1_TPR_C PF14853.6 EGR33380.1 - 0.088 12.9 0.1 19 5.4 0.0 3.8 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat VWA_2 PF13519.6 EGR33380.1 - 0.6 10.8 3.0 2.2 9.0 0.8 2.9 3 0 0 3 3 3 0 von Willebrand factor type A domain TPR_20 PF14561.6 EGR33380.1 - 9.9 6.6 8.9 0.99 9.8 0.1 3.1 2 1 1 3 3 2 0 Tetratricopeptide repeat DUF2012 PF09430.10 EGR33382.1 - 2.2e-12 47.2 0.5 3.2e-12 46.6 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 EGR33382.1 - 0.015 15.3 0.2 0.022 14.7 0.2 1.3 1 0 0 1 1 1 0 CarboxypepD_reg-like domain Y_Y_Y PF07495.13 EGR33382.1 - 0.031 14.2 2.0 0.04 13.9 1.0 1.8 1 1 0 1 1 1 0 Y_Y_Y domain CarboxypepD_reg PF13620.6 EGR33382.1 - 0.049 13.9 0.0 0.07 13.4 0.0 1.2 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain fn3_3 PF14686.6 EGR33382.1 - 0.065 13.0 0.4 0.1 12.4 0.4 1.3 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain II SdrD_B PF17210.3 EGR33382.1 - 0.078 13.2 0.1 0.11 12.7 0.1 1.2 1 0 0 1 1 1 0 SdrD B-like domain S1FA PF04689.13 EGR33383.1 - 0.012 15.7 0.1 0.012 15.7 0.1 1.8 2 0 0 2 2 2 0 DNA binding protein S1FA ABC_tran PF00005.27 EGR33384.1 - 6.9e-45 152.9 7.7 1.7e-22 80.4 0.0 3.1 4 0 0 4 4 2 2 ABC transporter ABC_tran_Xtn PF12848.7 EGR33384.1 - 4.9e-22 77.7 3.4 4.9e-22 77.7 3.4 4.3 4 1 0 4 4 4 1 ABC transporter AAA_21 PF13304.6 EGR33384.1 - 5e-14 52.8 17.5 5.1e-06 26.5 0.1 4.9 3 2 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGR33384.1 - 1.3e-12 47.7 1.8 0.0021 17.5 0.0 3.5 2 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGR33384.1 - 9.5e-06 25.7 0.4 0.013 15.6 0.0 2.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 EGR33384.1 - 4.8e-05 23.3 0.1 0.081 12.8 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_29 PF13555.6 EGR33384.1 - 5.1e-05 22.9 0.1 0.019 14.7 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGR33384.1 - 8.1e-05 22.6 1.7 0.051 13.5 0.1 3.4 2 1 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 EGR33384.1 - 0.00013 22.1 1.0 0.29 11.3 0.0 3.4 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EGR33384.1 - 0.00026 21.3 0.4 0.29 11.4 0.1 2.6 2 0 0 2 2 2 2 AAA domain AAA PF00004.29 EGR33384.1 - 0.00027 21.4 0.0 1 9.8 0.0 3.5 2 2 1 3 3 2 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 EGR33384.1 - 0.00038 20.7 0.5 0.27 11.5 0.1 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_24 PF13479.6 EGR33384.1 - 0.0011 18.8 0.4 1.4 8.6 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 EGR33384.1 - 0.0011 19.2 6.1 0.13 12.5 0.2 4.4 3 2 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EGR33384.1 - 0.0013 19.1 0.1 3.1 8.2 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_14 PF13173.6 EGR33384.1 - 0.0024 17.9 0.6 4 7.5 0.1 3.4 3 0 0 3 3 2 1 AAA domain YwhD PF08741.10 EGR33384.1 - 0.0042 16.8 0.7 0.011 15.4 0.7 1.7 1 0 0 1 1 1 1 YwhD family AAA_7 PF12775.7 EGR33384.1 - 0.013 15.1 0.1 3.7 7.0 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EGR33384.1 - 0.017 14.5 0.1 0.11 11.8 0.1 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.22 EGR33384.1 - 0.017 14.3 0.2 1.3 8.1 0.0 2.6 2 0 0 2 2 2 0 NB-ARC domain AAA_16 PF13191.6 EGR33384.1 - 0.017 15.5 0.2 1.7 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_23 PF13476.6 EGR33384.1 - 0.032 14.7 0.0 0.032 14.7 0.0 5.1 4 1 1 5 5 4 0 AAA domain TsaE PF02367.17 EGR33384.1 - 0.064 13.3 0.3 11 6.1 0.0 2.6 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Ras PF00071.22 EGR33384.1 - 0.086 12.4 0.6 2.5 7.7 0.0 2.6 2 1 0 2 2 2 0 Ras family AAA_30 PF13604.6 EGR33384.1 - 0.094 12.4 0.2 1.9 8.1 0.1 2.6 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 EGR33384.1 - 0.11 12.6 0.1 0.11 12.6 0.1 4.4 4 1 1 5 5 5 0 Helicase HerA, central domain AAA_15 PF13175.6 EGR33384.1 - 0.24 11.1 0.0 0.16 11.7 2.3 5.2 4 1 1 5 5 4 0 AAA ATPase domain MobB PF03205.14 EGR33384.1 - 0.36 10.7 5.5 3.8 7.4 0.1 4.1 4 0 0 4 4 4 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 EGR33384.1 - 1.3 9.6 9.3 1.2 9.6 0.5 3.8 3 1 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 EGR33384.1 - 3.2 7.8 13.3 0.46 10.5 0.1 3.5 4 1 0 4 4 3 0 Dynamin family Rhomboid_N PF12122.8 EGR33385.1 - 0.068 13.4 0.1 0.15 12.2 0.1 1.5 1 0 0 1 1 1 0 Cytoplasmic N-terminal domain of rhomboid serine protease ERGIC_N PF13850.6 EGR33386.1 - 0.00014 22.1 2.8 0.0017 18.6 0.2 2.7 2 0 0 2 2 2 2 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) EF-hand_7 PF13499.6 EGR33387.1 - 4.7e-12 46.2 0.1 6.1e-12 45.8 0.1 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGR33387.1 - 7.3e-11 40.8 0.1 9.9e-06 24.8 0.0 2.3 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGR33387.1 - 2.4e-09 36.3 0.1 0.0016 17.8 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGR33387.1 - 1e-08 34.4 0.1 1.3e-05 24.7 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGR33387.1 - 1.4e-05 24.8 0.2 0.16 11.9 0.0 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_10 PF14788.6 EGR33387.1 - 0.0083 16.0 0.4 0.056 13.3 0.0 2.4 1 1 1 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 EGR33387.1 - 0.017 15.5 0.1 0.11 12.9 0.1 1.9 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region SHMT PF00464.19 EGR33389.1 - 1.2e-185 616.9 0.6 1.7e-185 616.4 0.6 1.2 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Svf1_C PF17187.4 EGR33389.1 - 0.019 14.8 0.5 0.034 14.0 0.5 1.5 1 0 0 1 1 1 0 Svf1-like C-terminal lipocalin-like domain DegT_DnrJ_EryC1 PF01041.17 EGR33389.1 - 0.091 12.1 0.1 0.6 9.3 0.0 2.0 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Acyl-CoA_dh_1 PF00441.24 EGR33390.1 - 4.4e-26 91.9 0.1 6.6e-26 91.3 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGR33390.1 - 1.1e-17 63.9 0.1 1.8e-17 63.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGR33390.1 - 1.3e-17 64.5 0.0 2.6e-17 63.5 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGR33390.1 - 0.0048 17.2 0.0 0.0089 16.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 EGR33390.1 - 0.024 15.2 0.0 0.052 14.1 0.0 1.6 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal Mur_ligase_M PF08245.12 EGR33392.1 - 1.5e-05 25.1 0.9 3.5e-05 23.9 0.1 2.0 2 0 0 2 2 2 1 Mur ligase middle domain Mur_ligase_C PF02875.21 EGR33392.1 - 0.00027 21.1 0.0 0.0025 18.0 0.0 2.2 2 0 0 2 2 2 1 Mur ligase family, glutamate ligase domain DUF2666 PF10869.8 EGR33392.1 - 0.0029 17.8 5.9 0.012 15.8 0.4 3.4 2 1 2 4 4 4 1 Protein of unknown function (DUF2666) EF-hand_2 PF09068.11 EGR33392.1 - 1.5 9.0 6.2 1.8 8.7 0.5 2.9 3 0 0 3 3 3 0 EF hand Ras PF00071.22 EGR33393.1 - 7.7e-43 145.9 0.1 8.9e-43 145.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR33393.1 - 1.3e-24 86.7 0.0 2.5e-24 85.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR33393.1 - 3.3e-10 39.7 0.1 3.7e-10 39.5 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGR33393.1 - 0.004 16.7 0.4 0.0077 15.8 0.1 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGR33393.1 - 0.022 14.9 0.0 0.032 14.3 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase DDE_Tnp_1_assoc PF13808.6 EGR33393.1 - 0.13 12.3 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 DDE_Tnp_1-associated adh_short PF00106.25 EGR33394.1 - 3.7e-46 157.1 0.0 5.4e-46 156.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGR33394.1 - 1.2e-30 106.8 0.0 1.9e-30 106.2 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGR33394.1 - 2.3e-09 37.4 0.0 4.4e-09 36.5 0.0 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGR33394.1 - 0.027 13.8 0.0 0.046 13.1 0.0 1.4 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Pkinase PF00069.25 EGR33395.1 - 9.4e-58 195.6 0.3 1.4e-57 195.1 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33395.1 - 3.7e-24 85.4 0.1 5.1e-24 84.9 0.1 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33395.1 - 4.9e-06 26.1 0.0 9.4e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGR33395.1 - 0.017 15.1 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family ThiF PF00899.21 EGR33396.1 - 3.6e-81 272.1 0.0 4.1e-56 190.1 0.0 2.7 1 1 1 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EGR33396.1 - 8.2e-58 196.3 20.9 8.2e-58 196.3 20.9 6.0 5 1 0 5 5 5 1 Ubiquitin-activating enzyme active site UQ_con PF00179.26 EGR33396.1 - 1.8e-21 76.3 0.3 1.4e-20 73.3 0.0 2.8 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme E1_4HB PF16191.5 EGR33396.1 - 1.2e-12 47.8 1.4 5.8e-12 45.6 1.4 2.3 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_UFD PF09358.10 EGR33396.1 - 2.2e-06 28.3 1.7 2.2e-06 28.3 1.7 6.0 6 0 0 6 6 6 1 Ubiquitin fold domain UEV PF05743.13 EGR33396.1 - 0.00078 19.3 0.0 0.0077 16.1 0.0 2.9 1 0 0 1 1 1 1 UEV domain TMC PF07810.13 EGR33396.1 - 0.63 10.6 4.2 0.54 10.9 0.2 2.9 2 0 0 2 2 2 0 TMC domain DDHD PF02862.17 EGR33396.1 - 5.1 7.2 25.9 1.6 8.9 3.6 4.2 4 0 0 4 4 4 0 DDHD domain Cyclin PF08613.11 EGR33397.1 - 2.4e-36 125.6 1.8 2.7e-36 125.4 1.8 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EGR33397.1 - 3.9e-10 39.6 0.1 6.9e-10 38.8 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Multi_ubiq PF14452.6 EGR33397.1 - 0.018 15.3 0.0 0.03 14.6 0.0 1.3 1 0 0 1 1 1 0 Multiubiquitin SH3_5 PF08460.10 EGR33397.1 - 0.021 14.9 0.1 0.044 13.9 0.1 1.5 1 0 0 1 1 1 0 Bacterial SH3 domain Kinesin PF00225.23 EGR33399.1 - 1.2e-65 221.6 11.7 1.2e-65 221.6 11.7 2.3 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGR33399.1 - 1.7e-16 60.5 7.1 1.7e-16 60.5 7.1 4.5 4 2 0 4 4 4 1 Microtubule binding AAA_16 PF13191.6 EGR33399.1 - 0.052 13.9 0.2 0.17 12.3 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain OrfB_IS605 PF01385.19 EGR33399.1 - 0.49 10.6 10.0 0.026 14.8 2.6 2.6 3 0 0 3 3 3 0 Probable transposase Rav1p_C PF12234.8 EGR33400.1 - 1.9e-64 218.2 12.6 1.9e-64 218.2 12.6 2.2 2 1 1 3 3 3 2 RAVE protein 1 C terminal MORN PF02493.20 EGR33401.1 - 3.7e-61 199.5 83.8 7.3e-08 31.9 3.5 9.8 10 0 0 10 10 10 9 MORN repeat DUF448 PF04296.13 EGR33401.1 - 1.1 9.2 4.8 38 4.2 0.1 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF448) LRR_9 PF14580.6 EGR33402.1 - 7.8e-12 45.0 2.1 7.8e-12 45.0 2.1 3.0 2 1 1 3 3 3 2 Leucine-rich repeat LRR_4 PF12799.7 EGR33402.1 - 7.4e-08 32.6 13.9 6.8e-05 23.2 0.4 5.0 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGR33402.1 - 3.7e-06 26.6 6.9 0.00013 21.6 1.9 3.7 3 1 1 4 4 4 2 Leucine rich repeat NanE PF04131.14 EGR33402.1 - 0.046 12.9 2.0 3.2 6.9 0.0 2.4 2 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase LRR_6 PF13516.6 EGR33402.1 - 0.053 13.6 1.5 4.8 7.5 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeat Saf_2TM PF18303.1 EGR33402.1 - 0.081 12.5 4.0 0.15 11.7 4.0 1.4 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain MIR PF02815.19 EGR33403.1 - 1.5e-08 34.7 0.0 3.3e-08 33.6 0.0 1.6 1 1 0 1 1 1 1 MIR domain Glutaredoxin PF00462.24 EGR33404.1 - 5.9e-20 71.3 0.1 2.7e-13 49.9 0.0 3.4 3 1 0 3 3 3 2 Glutaredoxin Thioredoxin PF00085.20 EGR33404.1 - 4.5e-05 23.4 0.2 0.00042 20.3 0.0 2.4 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_3 PF13192.6 EGR33404.1 - 0.00022 21.2 0.1 0.13 12.4 0.0 3.3 3 2 0 3 3 3 1 Thioredoxin domain OST3_OST6 PF04756.13 EGR33404.1 - 0.00042 19.8 0.2 0.0033 16.8 0.1 2.1 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EGR33404.1 - 0.025 14.9 2.6 4.6 7.7 0.0 3.5 3 1 0 3 3 3 0 Thioredoxin-like HyaE PF07449.11 EGR33404.1 - 0.081 12.9 0.0 4.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE Kinesin PF00225.23 EGR33405.1 - 7.5e-22 77.7 4.6 6.5e-12 45.0 0.0 2.0 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EGR33405.1 - 5.6e-07 29.6 0.1 7e-07 29.3 0.1 1.2 1 0 0 1 1 1 1 Microtubule binding ResIII PF04851.15 EGR33405.1 - 0.041 13.9 0.0 0.051 13.6 0.0 1.2 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit PhoH PF02562.16 EGR33405.1 - 0.14 11.6 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 PhoH-like protein DUF87 PF01935.17 EGR33405.1 - 0.16 12.1 0.4 0.29 11.2 0.4 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain DEAD PF00270.29 EGR33405.1 - 0.2 11.4 0.0 0.23 11.2 0.0 1.1 1 0 0 1 1 1 0 DEAD/DEAH box helicase UPF0227 PF05728.12 EGR33406.1 - 2.6e-36 125.3 0.5 3.7e-36 124.8 0.5 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_6 PF12697.7 EGR33406.1 - 0.16 12.6 0.0 0.18 12.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Pkinase PF00069.25 EGR33407.1 - 2.6e-58 197.5 1.9 2.6e-58 197.5 1.9 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33407.1 - 9.9e-46 156.1 0.7 1.5e-45 155.6 0.7 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR33407.1 - 3.2e-05 22.9 0.1 5.9e-05 22.0 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR33407.1 - 0.016 14.6 0.1 0.035 13.5 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR33407.1 - 0.073 13.0 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family SNARE PF05739.19 EGR33408.1 - 1e-09 38.2 0.4 2.2e-09 37.1 0.4 1.6 1 0 0 1 1 1 1 SNARE domain DUF2203 PF09969.9 EGR33408.1 - 1.1 9.9 7.5 3.4 8.4 2.0 2.3 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF1664 PF07889.12 EGR33408.1 - 5.7 7.0 11.3 2.4 8.2 2.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) MORN PF02493.20 EGR33409.1 - 1.8e-49 162.7 60.3 8.1e-07 28.6 0.5 10.9 10 1 0 10 10 10 9 MORN repeat IQ PF00612.27 EGR33409.1 - 5.9e-07 28.7 1.2 1.2e-06 27.7 1.2 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Bot1p PF12298.8 EGR33409.1 - 0.3 11.2 2.1 0.17 12.1 0.2 1.4 2 0 0 2 2 2 0 Eukaryotic mitochondrial regulator protein zf_CCCH_4 PF18345.1 EGR33409.1 - 0.36 11.0 2.2 0.68 10.1 0.2 2.4 2 0 0 2 2 2 0 Zinc finger domain CsgF PF10614.9 EGR33409.1 - 1.9 8.7 5.4 4 7.7 0.7 2.5 2 1 0 2 2 2 0 Type VIII secretion system (T8SS), CsgF protein DnaJ_C PF01556.18 EGR33410.1 - 1.4e-35 122.5 0.9 2.1e-35 122.0 0.9 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGR33410.1 - 1.7e-19 69.7 0.5 2.9e-19 68.9 0.5 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGR33410.1 - 2.4e-15 56.6 23.0 5.7e-15 55.4 23.0 1.7 1 0 0 1 1 1 1 DnaJ central domain PBECR3 PF18812.1 EGR33410.1 - 0.03 14.3 0.5 0.085 12.8 0.2 1.9 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 Pkinase PF00069.25 EGR33411.1 - 9.5e-35 120.2 0.4 6.6e-32 110.9 0.1 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33411.1 - 5.3e-29 101.3 0.3 1.5e-27 96.5 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33411.1 - 0.00012 21.5 0.0 0.00044 19.7 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR33411.1 - 0.00064 18.6 0.0 0.001 17.9 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase GNAT_acetyltr_2 PF13718.6 EGR33411.1 - 0.12 11.7 0.6 0.17 11.2 0.6 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase 2 ABC1 PF03109.16 EGR33411.1 - 0.14 12.3 0.0 0.36 11.0 0.0 1.8 1 1 1 2 2 2 0 ABC1 family Aminotran_5 PF00266.19 EGR33412.1 - 1.4e-82 277.6 0.0 1.6e-82 277.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGR33412.1 - 3.3e-06 26.7 0.0 4.9e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 EGR33412.1 - 0.00014 21.3 0.2 0.00021 20.7 0.2 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.19 EGR33412.1 - 0.03 13.1 0.1 0.049 12.3 0.1 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain CBP_BcsG PF11658.8 EGR33412.1 - 0.12 10.7 0.0 0.18 10.2 0.0 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG TPR_2 PF07719.17 EGR33413.1 - 5.3e-28 94.9 23.4 3.5e-06 26.7 0.1 8.2 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGR33413.1 - 5.3e-28 95.6 29.4 7.2e-08 31.9 0.6 7.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGR33413.1 - 6e-24 84.1 8.0 1.9e-08 34.5 0.3 4.2 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGR33413.1 - 8.1e-21 73.4 24.1 9.7e-06 25.2 0.0 6.9 5 2 2 7 7 7 5 TPR repeat TPR_8 PF13181.6 EGR33413.1 - 3.2e-18 64.4 26.9 6.5e-06 26.0 0.1 7.7 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGR33413.1 - 1.8e-12 46.7 15.7 0.0014 18.9 0.2 7.7 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGR33413.1 - 6.5e-11 42.7 0.0 0.0037 17.9 0.0 5.0 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGR33413.1 - 3.3e-10 40.3 3.7 0.00084 19.8 0.2 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGR33413.1 - 1.5e-09 37.4 4.6 0.0027 17.5 0.0 5.2 5 1 1 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR33413.1 - 4.5e-09 36.4 16.3 0.002 18.3 0.6 4.3 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EGR33413.1 - 7.2e-09 35.7 0.0 0.18 12.7 0.0 5.1 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGR33413.1 - 1.3e-07 31.6 0.0 0.075 13.2 0.0 4.0 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGR33413.1 - 2.7e-07 30.1 3.6 0.025 14.6 0.0 5.8 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_21 PF09976.9 EGR33413.1 - 6.5e-06 26.0 0.1 0.1 12.3 0.0 2.4 1 1 0 2 2 2 2 Tetratricopeptide repeat-like domain TPR_6 PF13174.6 EGR33413.1 - 6.6e-05 23.3 10.8 7.9 7.4 0.1 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat Coatomer_E PF04733.14 EGR33413.1 - 0.00054 19.5 0.6 0.026 13.9 0.0 3.1 1 1 2 3 3 3 1 Coatomer epsilon subunit SHNi-TPR PF10516.9 EGR33413.1 - 0.088 12.3 5.7 15 5.2 0.1 4.6 4 0 0 4 4 4 0 SHNi-TPR PPR_2 PF13041.6 EGR33413.1 - 0.31 11.3 4.8 8.6 6.6 0.1 3.5 4 0 0 4 4 4 0 PPR repeat family HTH_Bact PF18768.1 EGR33413.1 - 0.54 9.9 10.4 0.043 13.4 2.7 3.3 3 1 0 3 3 3 0 Helix-turn-helix bacterial domain TPR_3 PF07720.12 EGR33413.1 - 1.7 8.7 9.4 6.6 6.8 0.1 3.7 4 0 0 4 4 3 0 Tetratricopeptide repeat PPR PF01535.20 EGR33413.1 - 3.7 8.0 5.2 6.1 7.3 0.0 3.6 5 0 0 5 5 4 0 PPR repeat Ribosomal_L27 PF01016.19 EGR33414.1 - 1.4e-28 98.7 4.5 8.6e-28 96.2 1.3 2.9 2 1 0 2 2 2 1 Ribosomal L27 protein cNMP_binding PF00027.29 EGR33414.1 - 7.4e-16 58.0 0.0 1.5e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGR33414.1 - 3e-11 43.1 2.4 5.8e-11 42.2 2.4 1.5 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGR33414.1 - 0.015 14.6 2.9 0.024 13.9 2.9 1.2 1 0 0 1 1 1 0 Ion transport protein DAHP_synth_2 PF01474.16 EGR33415.1 - 1.4e-127 425.8 1.3 1.1e-86 291.1 0.2 2.0 1 1 1 2 2 2 2 Class-II DAHP synthetase family ArsP_2 PF11449.8 EGR33416.1 - 0.49 9.6 1.5 0.56 9.3 1.5 1.0 1 0 0 1 1 1 0 Putative, 10TM heavy-metal exporter Pkinase PF00069.25 EGR33417.1 - 6.6e-38 130.6 0.0 8.8e-19 67.9 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33417.1 - 1.5e-22 80.2 0.0 7e-15 55.0 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGR33417.1 - 0.039 13.3 0.2 0.084 12.2 0.0 1.6 2 0 0 2 2 2 0 Kinase-like MORN PF02493.20 EGR33418.1 - 1e-33 113.2 72.9 1.4e-06 27.9 1.9 11.3 12 0 0 12 12 12 9 MORN repeat WEMBL PF05701.11 EGR33418.1 - 0.21 10.3 0.1 0.3 9.7 0.1 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light CDP-OH_P_transf PF01066.21 EGR33419.1 - 2e-11 44.5 1.3 2e-11 44.5 1.3 2.3 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DHHC PF01529.20 EGR33419.1 - 3.2 7.9 11.1 1.4 9.0 5.8 2.1 2 0 0 2 2 2 0 DHHC palmitoyltransferase DUF3267 PF11667.8 EGR33419.1 - 3.3 8.0 10.2 1.1 9.6 4.4 2.7 2 1 1 3 3 3 0 Putative zincin peptidase PA PF02225.22 EGR33420.1 - 1.2e-05 25.2 0.0 2.2e-05 24.4 0.0 1.4 1 0 0 1 1 1 1 PA domain Man-6-P_recep PF02157.15 EGR33420.1 - 0.0059 15.7 0.2 0.011 14.8 0.2 1.4 1 0 0 1 1 1 1 Mannose-6-phosphate receptor DUF2232 PF09991.9 EGR33420.1 - 0.037 13.2 0.4 0.064 12.4 0.4 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) FtsX PF02687.21 EGR33420.1 - 0.063 13.7 0.7 0.54 10.8 0.4 2.3 2 0 0 2 2 2 0 FtsX-like permease family YicC_N PF03755.13 EGR33420.1 - 0.15 12.5 0.7 0.36 11.3 0.0 1.9 3 0 0 3 3 3 0 YicC-like family, N-terminal region Tetraspanin PF00335.20 EGR33420.1 - 0.45 10.2 3.7 0.37 10.5 0.3 2.1 2 0 0 2 2 2 0 Tetraspanin family zf-CCHC PF00098.23 EGR33421.1 - 1.3e-37 126.2 83.5 7.4e-08 32.1 2.6 9.4 9 0 0 9 9 9 9 Zinc knuckle PhoR PF11808.8 EGR33422.1 - 0.58 10.6 3.3 0.32 11.4 0.7 1.9 1 1 1 2 2 2 0 Phosphate regulon sensor protein PhoR WD40 PF00400.32 EGR33424.1 - 0.00075 20.3 1.4 0.15 13.0 0.0 2.9 3 0 0 3 3 3 2 WD domain, G-beta repeat Tim17 PF02466.19 EGR33425.1 - 0.0018 18.6 0.0 0.0026 18.1 0.0 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF2816 PF10992.8 EGR33426.1 - 4.3e-22 77.7 29.9 8.8e-22 76.8 21.5 2.9 1 1 0 2 2 2 2 Protein of unknown function (DUF2816) Flu_B_NS1 PF02942.14 EGR33426.1 - 0.082 12.0 0.3 0.12 11.5 0.3 1.3 1 0 0 1 1 1 0 Influenza B non-structural protein (NS1) Pkinase PF00069.25 EGR33427.1 - 4.6e-62 209.8 0.5 6.3e-62 209.3 0.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33427.1 - 1e-29 103.6 0.0 1.4e-29 103.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR33427.1 - 6.6e-06 25.6 0.1 1.3e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR33427.1 - 8.4e-05 22.6 0.0 0.00061 19.8 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGR33427.1 - 0.0027 16.6 0.0 0.0049 15.7 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EGR33427.1 - 0.0036 16.8 1.4 0.0088 15.6 1.4 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL FTA2 PF13095.6 EGR33427.1 - 0.0038 16.9 8.2 0.025 14.2 0.5 2.9 3 0 0 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EGR33427.1 - 0.0041 16.5 0.1 0.014 14.7 0.0 2.0 1 1 0 1 1 1 1 Kinase-like PIP5K PF01504.18 EGR33428.1 - 3e-54 184.1 19.5 2.5e-44 151.5 13.4 3.2 3 1 0 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase EF-hand_7 PF13499.6 EGR33428.1 - 4.9e-09 36.5 2.6 1.3e-05 25.6 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR33428.1 - 5.6e-07 28.7 1.8 0.00015 21.0 0.1 2.8 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGR33428.1 - 0.0012 18.3 1.3 0.0018 17.7 0.1 2.0 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EGR33428.1 - 0.0026 17.6 0.1 0.25 11.2 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGR33428.1 - 0.004 17.0 4.6 0.023 14.6 0.5 3.0 2 0 0 2 2 2 1 EF-hand domain PFK PF00365.20 EGR33429.1 - 5e-57 193.4 0.3 6.9e-57 192.9 0.3 1.2 1 0 0 1 1 1 1 Phosphofructokinase Glyco_hydro_97 PF10566.9 EGR33429.1 - 0.0013 18.1 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Glycoside hydrolase 97 DAGK_cat PF00781.24 EGR33429.1 - 0.0034 17.0 0.1 0.0087 15.7 0.1 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain GARS_N PF02844.15 EGR33429.1 - 0.038 14.8 0.1 7.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain Peptidase_M14 PF00246.24 EGR33430.1 - 1.4e-18 67.8 0.1 1.8e-18 67.4 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase PhoLip_ATPase_C PF16212.5 EGR33431.1 - 6.4e-66 222.6 28.2 6.4e-66 222.6 28.2 2.2 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 EGR33431.1 - 1.3e-13 50.8 0.2 1.6e-12 47.3 0.1 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGR33431.1 - 3.2e-11 43.9 1.2 7.4e-05 23.1 0.1 3.2 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGR33431.1 - 0.87 9.1 4.1 0.42 10.1 0.9 2.2 2 0 0 2 2 2 0 E1-E2 ATPase zf-SAP30 PF13866.6 EGR33432.1 - 3.7 7.7 7.7 0.54 10.4 3.6 1.7 1 1 1 2 2 2 0 SAP30 zinc-finger ArfGap PF01412.18 EGR33433.1 - 2.9e-30 104.7 3.4 2.9e-30 104.7 3.4 3.2 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf Ish1 PF10281.9 EGR33433.1 - 0.018 15.3 1.0 0.49 10.7 0.2 3.1 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein SRTM1 PF15872.5 EGR33433.1 - 0.063 13.4 3.9 2.2 8.5 2.3 2.5 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 AAA_18 PF13238.6 EGR33433.1 - 1.6 9.3 6.7 0.33 11.5 2.0 2.2 2 1 0 2 2 2 0 AAA domain Pribosyltran_N PF13793.6 EGR33435.1 - 6.2e-36 122.9 0.1 1.6e-35 121.5 0.0 1.8 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase DUF3727 PF12527.8 EGR33436.1 - 0.069 13.4 8.5 0.62 10.3 0.1 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3727) RNB PF00773.19 EGR33437.1 - 4.8e-104 348.2 6.2 4.8e-104 348.2 6.2 2.3 2 1 0 2 2 2 1 RNB domain OB_Dis3 PF17849.1 EGR33437.1 - 1e-16 60.7 0.0 2.9e-16 59.2 0.0 1.8 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 EGR33437.1 - 6.9e-13 48.6 0.5 4.4e-12 45.9 0.3 2.3 2 0 0 2 2 2 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 EGR33437.1 - 1.7e-05 24.7 0.5 1.7e-05 24.7 0.5 3.2 3 1 1 4 4 4 1 S1 domain CSD2 PF17876.1 EGR33437.1 - 5.7e-05 23.2 0.1 0.05 13.8 0.0 3.1 2 0 0 2 2 2 2 Cold shock domain PIN_4 PF13638.6 EGR33437.1 - 5.8e-05 23.4 2.8 5.8e-05 23.4 2.8 3.3 3 1 0 3 3 3 1 PIN domain Dis3l2_C_term PF17877.1 EGR33437.1 - 0.0024 18.2 2.7 0.031 14.6 0.0 3.4 3 0 0 3 3 3 1 DIS3-like exonuclease 2 C terminal WD40 PF00400.32 EGR33438.1 - 4.2e-05 24.2 4.8 4.5 8.3 0.0 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat Atg29_N PF18388.1 EGR33438.1 - 9.4 6.2 6.9 2 8.3 3.3 1.7 2 0 0 2 2 2 0 Atg29 N-terminal domain ANAPC4_WD40 PF12894.7 EGR33439.1 - 2.9e-05 24.3 0.1 0.0025 18.1 0.0 2.1 1 1 1 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGR33439.1 - 0.00039 21.2 0.2 2.6 9.0 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat EF-hand_1 PF00036.32 EGR33440.1 - 2.1e-10 39.4 0.4 4.6e-05 22.7 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGR33440.1 - 1.1e-08 35.4 2.2 0.001 19.5 0.2 2.5 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EGR33440.1 - 9.7e-08 31.4 7.1 0.00056 19.6 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_8 PF13833.6 EGR33440.1 - 2.9e-07 30.2 0.1 0.00058 19.7 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGR33440.1 - 8.8e-07 28.1 3.6 0.00038 19.8 0.1 3.3 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 EGR33440.1 - 0.022 15.1 0.3 0.022 15.1 0.3 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region TrmB PF01978.19 EGR33440.1 - 0.14 12.1 0.0 7.4 6.5 0.0 2.5 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB PP-binding PF00550.25 EGR33441.1 - 1.8e-10 41.0 0.1 2.1e-10 40.8 0.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Hist_deacetyl PF00850.19 EGR33444.1 - 7.1e-22 78.3 0.0 1e-21 77.8 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain Alpha_Helical PF18489.1 EGR33444.1 - 0.027 14.6 1.1 0.043 14.0 0.2 1.8 2 0 0 2 2 2 0 Alpha helical domain CitMHS PF03600.16 EGR33444.1 - 0.84 8.8 5.6 1.3 8.1 5.6 1.3 1 0 0 1 1 1 0 Citrate transporter EI24 PF07264.11 EGR33444.1 - 5.2 7.3 9.8 8.9 6.5 9.8 1.4 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Furin-like_2 PF15913.5 EGR33445.1 - 2.1 8.5 121.3 0.087 13.0 27.3 7.4 1 1 4 5 5 5 0 Furin-like repeat, cysteine-rich DUF2403 PF10290.9 EGR33447.1 - 0.048 14.1 0.0 0.2 12.1 0.0 2.1 1 0 0 1 1 1 0 Glycine-rich protein domain (DUF2403) DUF4637 PF15470.6 EGR33447.1 - 0.049 13.4 0.2 0.049 13.4 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) PAS_9 PF13426.7 EGR33447.1 - 0.049 13.9 4.4 0.37 11.1 0.0 3.8 3 1 1 4 4 4 0 PAS domain Thioredoxin_8 PF13905.6 EGR33447.1 - 0.56 10.6 4.9 0.29 11.5 0.8 2.7 2 0 0 2 2 2 0 Thioredoxin-like DUF499 PF04465.12 EGR33448.1 - 0.03 12.1 0.0 0.036 11.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF499) Tyrosinase PF00264.20 EGR33449.1 - 0.37 11.1 9.6 0.54 10.5 9.6 1.1 1 0 0 1 1 1 0 Common central domain of tyrosinase Organ_specific PF10950.8 EGR33449.1 - 6.3 7.5 13.9 4 8.2 11.6 1.9 1 1 1 2 2 2 0 Organ specific protein Furin-like_2 PF15913.5 EGR33450.1 - 9.2 6.5 38.9 0.41 10.8 10.9 3.5 1 1 2 3 3 3 0 Furin-like repeat, cysteine-rich PTEN_C2 PF10409.9 EGR33452.1 - 3.6e-21 75.3 5.1 6.7e-21 74.5 5.1 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 EGR33452.1 - 1.2e-08 34.8 0.3 5.1e-08 32.8 0.3 2.2 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGR33452.1 - 4.7e-05 23.1 0.0 0.0001 22.0 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EGR33452.1 - 0.00035 20.6 0.0 0.00053 20.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EGR33452.1 - 0.0088 16.2 0.5 0.02 15.0 0.5 1.6 1 1 0 1 1 1 1 Inositol hexakisphosphate DUF5077 PF16871.5 EGR33453.1 - 4.1e-15 56.2 0.2 5e-15 55.9 0.2 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF5077) YueH PF14166.6 EGR33453.1 - 0.012 15.4 0.4 1.2 9.1 0.1 2.2 2 0 0 2 2 2 0 YueH-like protein DUF3472 PF11958.8 EGR33454.1 - 4.5e-69 232.3 0.5 5.9e-69 232.0 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 EGR33454.1 - 0.00085 19.3 1.4 0.00085 19.3 1.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5077) MFS_1 PF07690.16 EGR33456.1 - 2e-20 73.0 27.5 2.7e-20 72.6 21.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily PsaD PF02531.16 EGR33457.1 - 0.05 13.1 1.3 4.8 6.7 0.1 3.5 2 1 1 3 3 3 0 PsaD DUF2816 PF10992.8 EGR33458.1 - 3.1e-20 71.8 20.5 3.1e-20 71.8 20.5 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF2816) DUF4539 PF15072.6 EGR33458.1 - 0.033 14.2 0.0 5.5 7.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4539) Sod_Cu PF00080.20 EGR33459.1 - 3.6e-29 101.8 1.3 6.9e-29 100.8 1.3 1.4 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DNA_primase_S PF01896.19 EGR33459.1 - 1.5e-28 100.0 2.4 2.2e-28 99.5 2.4 1.2 1 0 0 1 1 1 1 DNA primase small subunit Mito_carr PF00153.27 EGR33460.1 - 2e-40 136.6 1.9 6.9e-15 54.8 0.0 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein Meckelin PF09773.9 EGR33461.1 - 6.1e-57 193.3 1.6 7.4e-57 193.1 1.6 1.0 1 0 0 1 1 1 1 Meckelin (Transmembrane protein 67) Thioredoxin PF00085.20 EGR33462.1 - 3.6e-07 30.1 0.1 6.1e-07 29.4 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 EGR33462.1 - 7.3e-05 22.7 0.7 0.00016 21.6 0.6 1.9 1 1 0 1 1 1 1 AhpC/TSA family DIM1 PF02966.16 EGR33462.1 - 0.00032 20.5 0.1 0.00044 20.0 0.1 1.2 1 0 0 1 1 1 1 Mitosis protein DIM1 TraF PF13728.6 EGR33462.1 - 0.0024 17.7 0.4 0.004 17.0 0.1 1.5 1 1 1 2 2 2 1 F plasmid transfer operon protein Thioredoxin_2 PF13098.6 EGR33462.1 - 0.0064 16.9 1.0 0.086 13.3 0.3 2.6 1 1 1 2 2 2 1 Thioredoxin-like domain FtsX_ECD PF18075.1 EGR33462.1 - 0.0077 16.8 1.4 0.0077 16.8 1.4 2.3 1 1 0 2 2 2 1 FtsX extracellular domain CdvA PF18822.1 EGR33462.1 - 0.018 14.9 2.3 3.3 7.5 0.2 2.5 2 0 0 2 2 2 0 CdvA-like coiled-coil domain Thioredoxin_8 PF13905.6 EGR33462.1 - 0.023 15.0 1.9 0.062 13.6 1.0 2.3 1 1 1 2 2 2 0 Thioredoxin-like DUF5595 PF18077.1 EGR33462.1 - 0.025 14.6 2.0 0.025 14.6 2.0 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) GCN5L1 PF06320.13 EGR33462.1 - 0.046 13.9 0.8 0.046 13.9 0.8 1.7 3 0 0 3 3 2 0 GCN5-like protein 1 (GCN5L1) YtxH PF12732.7 EGR33462.1 - 0.077 13.5 2.9 0.14 12.7 1.2 2.1 2 1 0 2 2 2 0 YtxH-like protein Redoxin PF08534.10 EGR33462.1 - 0.14 11.9 0.0 0.17 11.6 0.0 1.4 1 1 0 1 1 1 0 Redoxin Occludin_ELL PF07303.13 EGR33462.1 - 0.96 10.2 14.5 8.9 7.1 0.1 3.5 1 1 2 3 3 3 0 Occludin homology domain UCH PF00443.29 EGR33463.1 - 4.4e-25 88.7 3.2 7.1e-25 88.0 3.2 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_L27e PF01777.18 EGR33465.1 - 7.8e-29 99.9 7.2 1.2e-28 99.3 7.2 1.3 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 EGR33465.1 - 0.0014 18.5 1.7 0.0024 17.8 0.6 1.9 2 0 0 2 2 2 1 KOW motif PP28 PF10252.9 EGR33466.1 - 4.9 7.7 42.2 0.75 10.3 24.4 3.6 2 1 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 DUF3336 PF11815.8 EGR33468.1 - 3.8e-36 123.8 7.1 1e-35 122.4 7.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Patatin PF01734.22 EGR33468.1 - 1.6e-21 77.4 0.0 3e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase Thioredoxin PF00085.20 EGR33469.1 - 4.4e-66 219.4 0.8 4.1e-32 110.2 0.2 2.8 3 0 0 3 3 3 2 Thioredoxin OST3_OST6 PF04756.13 EGR33469.1 - 8.2e-15 54.9 0.3 1.2e-09 38.0 0.1 2.8 3 0 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_6 PF13848.6 EGR33469.1 - 2.8e-11 43.7 1.2 1.3e-07 31.7 0.5 3.0 2 1 1 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EGR33469.1 - 8.4e-11 42.3 1.8 0.00045 20.6 0.1 4.1 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGR33469.1 - 1.3e-05 25.4 1.2 0.75 10.2 0.1 5.2 3 3 2 5 5 5 1 Thioredoxin-like AhpC-TSA PF00578.21 EGR33469.1 - 2.3e-05 24.3 0.1 0.021 14.7 0.1 2.8 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_7 PF13899.6 EGR33469.1 - 2.5e-05 24.4 0.0 0.26 11.5 0.0 2.8 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 EGR33469.1 - 0.0016 18.2 0.0 2.4 7.9 0.0 2.7 3 0 0 3 3 3 2 Thioredoxin Redoxin PF08534.10 EGR33469.1 - 0.0036 17.0 0.9 7.7 6.2 0.1 3.5 3 1 0 3 3 3 1 Redoxin Thioredoxin_3 PF13192.6 EGR33469.1 - 0.0076 16.3 0.0 3.6 7.7 0.0 2.5 2 0 0 2 2 2 1 Thioredoxin domain DDE_Tnp_1_2 PF13586.6 EGR33469.1 - 0.025 15.0 0.0 3.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Transposase DDE domain DIM1 PF02966.16 EGR33469.1 - 0.037 13.8 0.0 0.13 12.1 0.0 1.9 2 0 0 2 2 2 0 Mitosis protein DIM1 Spaetzle PF16077.5 EGR33469.1 - 0.063 13.8 0.1 0.16 12.6 0.1 1.6 1 0 0 1 1 1 0 Spaetzle HyaE PF07449.11 EGR33469.1 - 0.088 12.8 0.0 4.7 7.2 0.0 2.7 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE DUF2280 PF10045.9 EGR33469.1 - 0.13 12.5 0.0 4.6 7.6 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2280) Thioredoxin_5 PF13743.6 EGR33469.1 - 0.4 10.3 8.0 6 6.5 0.0 4.4 3 2 3 6 6 6 0 Thioredoxin HEAT PF02985.22 EGR33470.1 - 9.2e-39 128.2 6.3 0.015 15.5 0.0 12.7 14 0 0 14 14 14 8 HEAT repeat HEAT_2 PF13646.6 EGR33470.1 - 5.6e-28 97.2 0.0 3.2e-05 24.2 0.0 8.3 2 2 6 8 8 8 8 HEAT repeats Vac14_Fab1_bd PF12755.7 EGR33470.1 - 2.9e-13 50.2 14.6 0.00045 20.8 0.2 7.8 2 1 7 9 9 9 4 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EGR33470.1 - 2.2e-11 43.7 8.2 0.019 14.5 0.0 5.5 1 1 2 5 5 5 4 CLASP N terminal Adaptin_N PF01602.20 EGR33470.1 - 2.8e-10 39.4 18.6 0.00011 20.9 9.2 3.8 1 1 1 3 3 3 3 Adaptin N terminal region HEAT_EZ PF13513.6 EGR33470.1 - 5.7e-06 26.7 2.4 16 6.1 0.0 7.0 7 1 0 7 7 7 0 HEAT-like repeat RTP1_C1 PF10363.9 EGR33470.1 - 5.4e-05 23.3 7.8 1.5 9.0 0.3 5.4 3 3 2 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 DUF61 PF01886.16 EGR33470.1 - 0.00069 19.7 4.8 0.058 13.4 1.2 3.2 3 1 0 3 3 3 2 Protein of unknown function DUF61 UME PF08064.13 EGR33470.1 - 0.00076 19.4 0.4 0.95 9.4 0.0 4.3 3 1 1 4 4 4 1 UME (NUC010) domain DUF4042 PF13251.6 EGR33470.1 - 0.0013 18.5 0.7 5.2 6.7 0.2 4.6 2 1 1 4 4 4 2 Domain of unknown function (DUF4042) V-ATPase_H_C PF11698.8 EGR33470.1 - 1.5 9.0 7.8 0.93 9.6 0.1 4.2 4 2 0 4 4 4 0 V-ATPase subunit H ParcG PF10274.9 EGR33472.1 - 1.2e-63 214.5 0.3 1.6e-63 214.1 0.3 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 EGR33472.1 - 0.071 12.8 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 MORN PF02493.20 EGR33473.1 - 2.1e-21 74.5 27.2 2.9e-05 23.7 1.6 5.8 5 0 0 5 5 5 5 MORN repeat Pkinase_Tyr PF07714.17 EGR33473.1 - 8.5e-10 38.3 1.0 1.3e-09 37.7 1.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGR33473.1 - 1.6e-07 31.0 3.1 4.4e-07 29.5 3.0 1.8 1 1 0 1 1 1 1 Protein kinase domain MORN_2 PF07661.13 EGR33473.1 - 1.1 9.7 11.5 2.8 8.5 0.0 4.8 3 0 0 3 3 3 0 MORN repeat variant Rhomboid_N PF12122.8 EGR33473.1 - 4 7.7 7.9 18 5.6 7.9 2.1 1 1 0 1 1 1 0 Cytoplasmic N-terminal domain of rhomboid serine protease GILT PF03227.16 EGR33474.1 - 6.1e-28 97.2 2.7 6.1e-28 97.2 2.7 2.0 1 1 1 2 2 2 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Thioredoxin_4 PF13462.6 EGR33474.1 - 0.00015 22.0 0.2 0.57 10.3 0.0 2.2 2 0 0 2 2 2 2 Thioredoxin Histone_H2A_C PF16211.5 EGR33475.1 - 9.6e-18 63.6 0.4 2e-17 62.6 0.4 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGR33475.1 - 1.9e-14 54.2 0.0 2.7e-14 53.7 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGR33475.1 - 4.5e-05 23.6 0.0 7.6e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YihI PF04220.12 EGR33475.1 - 0.089 12.5 0.1 0.17 11.6 0.1 1.5 1 1 0 1 1 1 0 Der GTPase activator (YihI) NDK PF00334.19 EGR33476.1 - 4.9e-55 185.2 0.0 5.9e-55 185.0 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase MIP-T3_C PF17749.1 EGR33476.1 - 0.052 13.5 1.2 4.5 7.2 0.4 2.3 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Pkinase PF00069.25 EGR33477.1 - 6.1e-48 163.5 2.2 1e-47 162.8 2.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33477.1 - 3.9e-19 68.9 0.7 2.3e-18 66.4 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EGR33477.1 - 0.056 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SR-25 PF10500.9 EGR33477.1 - 0.86 9.2 11.9 0.063 12.9 6.2 1.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SSP160 PF06933.11 EGR33477.1 - 1.1 7.3 4.8 1.6 6.8 4.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 IMUP PF15761.5 EGR33477.1 - 2 9.2 9.9 4.7 7.9 9.9 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein Costars PF14705.6 EGR33478.1 - 9.4e-28 96.2 0.9 1.1e-27 96.0 0.9 1.0 1 0 0 1 1 1 1 Costars Osmo_CC PF08946.10 EGR33478.1 - 2.5 8.4 6.2 17 5.8 2.4 2.5 2 1 0 2 2 2 0 Osmosensory transporter coiled coil Metallophos PF00149.28 EGR33480.1 - 2.7e-34 119.5 0.4 3.7e-34 119.0 0.4 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NPL PF17800.1 EGR33481.1 - 9.1e-18 64.8 0.0 9.1e-18 64.8 0.0 4.3 2 1 0 2 2 2 1 Nucleoplasmin-like domain RRM_1 PF00076.22 EGR33482.1 - 4.2e-05 23.3 0.0 9.8e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGR33482.1 - 0.0057 16.6 0.1 0.012 15.6 0.1 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif EIF_2_alpha PF07541.12 EGR33483.1 - 7.7e-32 109.8 3.9 4.3e-31 107.4 0.1 2.7 3 0 0 3 3 3 1 Eukaryotic translation initiation factor 2 alpha subunit S1 PF00575.23 EGR33483.1 - 8.6e-05 22.8 0.5 0.00018 21.7 0.5 1.6 1 0 0 1 1 1 1 S1 RNA binding domain HAUS2 PF15003.6 EGR33483.1 - 0.0045 16.7 0.3 0.007 16.1 0.3 1.4 1 1 0 1 1 1 1 HAUS augmin-like complex subunit 2 RNA_pol_3_Rpc31 PF11705.8 EGR33483.1 - 0.16 12.2 12.4 0.3 11.3 12.4 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 LRR_8 PF13855.6 EGR33484.1 - 8.7e-27 92.7 59.7 2.8e-10 39.8 4.2 6.1 2 1 5 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 EGR33484.1 - 1.3e-23 82.7 51.8 4.2e-07 30.2 0.5 6.5 5 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGR33484.1 - 1.2e-12 47.7 28.6 3.7e-09 36.3 2.7 3.2 1 1 1 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 EGR33484.1 - 0.0003 20.6 28.4 5 7.4 1.0 8.4 8 0 0 8 8 8 3 Leucine Rich repeat DUF4110 PF13422.6 EGR33484.1 - 0.57 10.3 7.8 0.33 11.0 3.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) Flt3_lig PF02947.14 EGR33484.1 - 0.94 9.7 4.9 2.5 8.3 0.3 3.3 1 1 2 3 3 3 0 flt3 ligand LRR_1 PF00560.33 EGR33484.1 - 2.1 9.2 37.0 44 5.2 0.7 9.1 7 2 0 7 7 7 0 Leucine Rich Repeat EF-hand_7 PF13499.6 EGR33485.1 - 6.4e-21 74.6 13.1 1.4e-08 35.1 1.4 4.8 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 EGR33485.1 - 4.5e-19 66.7 17.6 0.00062 19.5 0.1 7.8 7 0 0 7 7 7 4 EF-hand domain EF-hand_1 PF00036.32 EGR33485.1 - 1.1e-13 49.7 14.1 0.00086 18.7 0.2 6.1 6 1 1 7 7 7 4 EF hand EF-hand_5 PF13202.6 EGR33485.1 - 8e-06 25.1 10.7 0.034 13.6 0.2 4.8 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EGR33485.1 - 2.1e-05 24.3 11.3 0.041 13.7 0.3 4.8 3 2 2 5 5 5 3 EF-hand domain pair EFhand_Ca_insen PF08726.10 EGR33485.1 - 6.4e-05 23.0 3.1 2.5 8.3 0.0 5.0 4 1 1 5 5 5 1 Ca2+ insensitive EF hand SPARC_Ca_bdg PF10591.9 EGR33485.1 - 5.8 7.3 7.8 5.8 7.3 0.4 4.1 3 1 0 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region HECT PF00632.25 EGR33486.1 - 1.1e-86 291.1 6.0 1.5e-86 290.7 6.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) PEP_mutase PF13714.6 EGR33487.1 - 9e-44 149.7 0.0 1e-43 149.5 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EGR33487.1 - 6.4e-14 51.3 0.0 1.5e-13 50.1 0.0 1.5 2 0 0 2 2 2 1 Isocitrate lyase family TPR_1 PF00515.28 EGR33488.1 - 0.12 12.3 1.1 10 6.2 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat MORN PF02493.20 EGR33489.1 - 4e-51 167.9 70.2 1.2e-07 31.2 1.1 10.7 11 0 0 11 11 11 10 MORN repeat Tim44 PF04280.15 EGR33489.1 - 4.6e-06 26.8 0.1 2.7e-05 24.3 0.1 2.1 1 1 0 1 1 1 1 Tim44-like domain AbiGi PF10899.8 EGR33489.1 - 0.017 15.0 2.4 0.038 13.8 2.4 1.6 1 1 0 1 1 1 0 Putative abortive phage resistance protein AbiGi, antitoxin VASt PF16016.5 EGR33490.1 - 5.2e-05 23.7 0.2 9.7e-05 22.8 0.1 1.4 1 1 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain MMPL PF03176.15 EGR33491.1 - 0.25 10.2 1.8 0.32 9.9 1.8 1.1 1 0 0 1 1 1 0 MMPL family Acetyltransf_3 PF13302.7 EGR33492.1 - 4e-18 66.4 0.0 5e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGR33492.1 - 4.7e-07 30.1 5.6 6.9e-07 29.5 5.6 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGR33492.1 - 6.3e-07 29.6 0.0 8e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EGR33492.1 - 0.023 14.4 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SHS2_Rpb7-N PF03876.17 EGR33493.1 - 0.0029 17.9 0.0 0.0079 16.6 0.0 1.8 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Orn_Arg_deC_N PF02784.16 EGR33494.1 - 5.1e-30 104.6 0.0 7.7e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain E3_binding PF02817.17 EGR33494.1 - 0.013 15.8 0.0 0.027 14.8 0.0 1.5 1 0 0 1 1 1 0 e3 binding domain AP_endonuc_2 PF01261.24 EGR33494.1 - 0.04 13.3 0.0 0.059 12.8 0.0 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Orn_DAP_Arg_deC PF00278.22 EGR33494.1 - 0.079 13.2 0.0 0.089 13.0 0.0 1.3 1 1 0 1 1 1 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Cyt-b5 PF00173.28 EGR33495.1 - 4.2e-07 30.0 0.0 1.1e-06 28.7 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RNase_H_2 PF13482.6 EGR33495.1 - 0.019 15.0 1.1 0.036 14.1 0.1 1.8 2 0 0 2 2 2 0 RNase_H superfamily tRNA-synt_1c PF00749.21 EGR33496.1 - 3.1e-102 341.7 0.5 4e-102 341.3 0.5 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGR33496.1 - 9.8e-35 120.0 0.5 9.8e-35 120.0 0.5 2.1 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA-synt_1e PF01406.19 EGR33496.1 - 0.0014 18.1 0.1 0.0028 17.1 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Atx10homo_assoc PF09759.9 EGR33497.1 - 0.0025 17.8 3.5 0.038 14.0 0.2 3.5 2 1 1 3 3 3 1 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 EGR33497.1 - 0.017 15.1 3.5 0.06 13.3 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF3361) Drf_DAD PF06345.11 EGR33497.1 - 0.023 14.7 0.2 0.25 11.5 0.0 2.4 2 0 0 2 2 2 0 DRF Autoregulatory Domain Pkinase PF00069.25 EGR33498.1 - 4.5e-72 242.6 0.2 8.8e-72 241.6 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33498.1 - 2.5e-42 145.0 0.1 7.9e-42 143.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase POLO_box PF00659.18 EGR33498.1 - 5.2e-40 135.5 3.2 3.5e-20 71.9 0.1 2.9 2 0 0 2 2 2 2 POLO box duplicated region Kinase-like PF14531.6 EGR33498.1 - 2.2e-11 43.6 0.0 1.6e-08 34.3 0.0 2.7 1 1 2 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 EGR33498.1 - 9.6e-09 34.5 0.0 9.6e-09 34.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase PUF PF00806.19 EGR33501.1 - 7.8e-42 138.7 23.4 7.4e-07 28.5 0.1 7.5 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat Peptidase_C2 PF00648.21 EGR33502.1 - 0.044 12.8 0.7 0.043 12.9 0.7 1.1 1 0 0 1 1 1 0 Calpain family cysteine protease CK_II_beta PF01214.18 EGR33503.1 - 6.1e-48 163.0 0.5 1.9e-47 161.4 0.0 1.8 2 0 0 2 2 2 1 Casein kinase II regulatory subunit Nop52 PF05997.12 EGR33505.1 - 4e-23 82.3 6.9 4.4e-23 82.2 6.9 1.1 1 0 0 1 1 1 1 Nucleolar protein,Nop52 FmdE PF02663.14 EGR33505.1 - 0.011 15.8 1.1 0.014 15.4 1.1 1.2 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Csm2_III-A PF03750.13 EGR33505.1 - 0.093 13.6 0.7 0.093 13.6 0.7 2.0 1 1 1 2 2 2 0 Csm2 Type III-A Nkap_C PF06047.11 EGR33506.1 - 1.7e-45 153.3 2.1 1.7e-45 153.3 2.1 3.8 4 1 0 4 4 4 1 NF-kappa-B-activating protein C-terminal domain DUF3446 PF11928.8 EGR33506.1 - 3.4 8.1 19.2 0.61 10.4 8.9 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain zf-CHY PF05495.12 EGR33507.1 - 8.4e-14 51.8 14.7 1.7e-13 50.8 14.7 1.5 1 1 0 1 1 1 1 CHY zinc finger RNA_POL_M_15KD PF02150.16 EGR33507.1 - 0.0098 15.7 7.2 0.22 11.4 0.0 3.2 2 1 1 3 3 3 1 RNA polymerases M/15 Kd subunit NOB1_Zn_bind PF08772.11 EGR33507.1 - 0.019 15.1 5.0 0.019 15.1 5.0 2.0 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Zn_Tnp_IS91 PF14319.6 EGR33507.1 - 0.62 10.1 13.8 0.15 12.1 1.7 2.1 1 1 1 2 2 2 0 Transposase zinc-binding domain C1_4 PF07975.12 EGR33507.1 - 2.1 8.7 15.5 9.5 6.5 0.4 2.9 1 1 2 3 3 3 0 TFIIH C1-like domain RecQ_Zn_bind PF16124.5 EGR33507.1 - 2.2 9.1 12.8 4.9 8.0 12.9 1.4 1 1 0 1 1 1 0 RecQ zinc-binding Zn-ribbon_8 PF09723.10 EGR33507.1 - 7.3 6.8 16.5 0.55 10.4 6.2 2.8 3 0 0 3 3 3 0 Zinc ribbon domain Thioredoxin PF00085.20 EGR33508.1 - 4.2e-25 87.7 1.6 1.8e-24 85.7 0.1 2.7 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.6 EGR33508.1 - 2.3e-18 66.7 24.2 1.9e-17 63.8 11.4 2.8 1 1 2 3 3 3 2 Thioredoxin-like domain ERp29_N PF07912.13 EGR33508.1 - 2.5e-06 27.7 2.5 0.0047 17.1 0.1 2.5 2 0 0 2 2 2 2 ERp29, N-terminal domain OST3_OST6 PF04756.13 EGR33508.1 - 7.4e-06 25.5 1.3 7.4e-06 25.5 1.3 1.9 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EGR33508.1 - 0.00014 22.3 3.0 0.00082 19.8 0.3 3.1 1 1 1 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EGR33508.1 - 0.001 19.2 0.5 0.042 14.0 0.0 2.7 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.6 EGR33508.1 - 0.0018 18.6 15.6 0.023 15.0 0.2 4.2 1 1 3 5 5 5 2 Thioredoxin-like AhpC-TSA PF00578.21 EGR33508.1 - 0.027 14.4 1.2 0.099 12.6 0.1 2.4 3 0 0 3 3 3 0 AhpC/TSA family Redoxin PF08534.10 EGR33508.1 - 0.84 9.3 4.9 5.4 6.7 0.0 3.2 3 1 1 4 4 4 0 Redoxin Sod_Fe_C PF02777.18 EGR33509.1 - 8e-34 115.9 3.0 8.5e-34 115.8 1.1 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EGR33509.1 - 4.1e-25 88.1 3.2 7.3e-25 87.3 3.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain GrpE PF01025.19 EGR33510.1 - 1e-17 64.3 1.6 1.1e-17 64.2 1.6 1.0 1 0 0 1 1 1 1 GrpE Nucleoporin_FG PF13634.6 EGR33511.1 - 0.00036 21.3 37.5 0.0029 18.4 16.9 3.0 1 1 1 2 2 2 1 Nucleoporin FG repeat region MMU163 PF17119.5 EGR33511.1 - 0.051 12.7 4.9 0.086 12.0 4.9 1.3 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis NMO PF03060.15 EGR33511.1 - 0.13 11.7 1.6 0.17 11.3 0.3 1.8 2 0 0 2 2 2 0 Nitronate monooxygenase DUF4746 PF15928.5 EGR33511.1 - 0.72 9.2 10.0 1.4 8.3 10.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SseC PF04888.12 EGR33511.1 - 2.1 7.9 14.9 3.1 7.3 14.9 1.2 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Presenilin PF01080.17 EGR33511.1 - 6.2 5.5 8.6 10 4.7 8.6 1.3 1 0 0 1 1 1 0 Presenilin CTP_synth_N PF06418.14 EGR33512.1 - 1.2e-105 352.6 1.5 3.4e-105 351.1 1.5 1.8 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EGR33512.1 - 5.3e-19 68.7 2.6 5.3e-19 68.7 2.6 3.2 3 1 1 4 4 4 2 Glutamine amidotransferase class-I CbiA PF01656.23 EGR33512.1 - 0.073 13.1 0.0 0.18 11.9 0.0 1.8 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain Ank_4 PF13637.6 EGR33513.1 - 9.5e-07 29.3 0.0 0.0078 16.8 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGR33513.1 - 0.0013 19.1 0.0 2.6 8.7 0.0 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 EGR33513.1 - 0.0014 19.2 0.3 0.092 13.4 0.3 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGR33513.1 - 0.0047 17.3 0.0 1.4 9.7 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat COPIIcoated_ERV PF07970.12 EGR33515.1 - 7.6e-35 120.8 3.5 1e-34 120.3 3.5 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGR33515.1 - 1.2e-10 41.6 0.2 5.4e-10 39.5 0.0 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Pkinase PF00069.25 EGR33516.1 - 4.5e-23 81.9 0.3 2e-13 50.3 0.0 3.0 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33516.1 - 2.6e-07 30.2 0.0 0.0027 17.0 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase VOMI PF03762.17 EGR33516.1 - 0.063 13.4 0.3 1.2 9.3 0.0 2.1 2 0 0 2 2 2 0 Vitelline membrane outer layer protein I (VOMI) DUF1992 PF09350.10 EGR33516.1 - 0.13 12.5 0.2 0.35 11.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1992) Adhes-Ig_like PF09085.10 EGR33517.1 - 3.9 7.6 7.4 0.33 11.1 1.2 2.3 2 1 0 2 2 2 0 Adhesion molecule, immunoglobulin-like DUF1963 PF09234.10 EGR33518.1 - 0.75 10.2 12.7 0.17 12.3 2.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1963) 14-3-3 PF00244.20 EGR33519.1 - 9.1e-78 260.8 12.0 1.1e-77 260.5 12.0 1.0 1 0 0 1 1 1 1 14-3-3 protein ApbE PF02424.15 EGR33519.1 - 0.065 12.8 0.2 0.093 12.2 0.2 1.2 1 0 0 1 1 1 0 ApbE family NifW PF03206.14 EGR33519.1 - 0.071 13.6 1.1 1.4 9.5 0.1 2.6 2 0 0 2 2 2 0 Nitrogen fixation protein NifW Peptidase_M16 PF00675.20 EGR33519.1 - 2.6 8.0 5.9 3.6 7.6 0.3 2.7 3 0 0 3 3 3 0 Insulinase (Peptidase family M16) Trep_Strep PF09605.10 EGR33520.1 - 0.0097 15.9 0.7 0.01 15.8 0.7 1.0 1 0 0 1 1 1 1 Hypothetical bacterial integral membrane protein (Trep_Strep) Sugar_tr PF00083.24 EGR33520.1 - 0.047 12.5 2.0 0.066 12.1 2.0 1.3 1 0 0 1 1 1 0 Sugar (and other) transporter DUF4771 PF15995.5 EGR33521.1 - 0.055 13.7 0.1 3.7 7.8 0.0 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4771) WD40 PF00400.32 EGR33522.1 - 1.2e-19 70.2 9.2 1.8e-06 28.6 0.2 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR33522.1 - 2.4e-15 56.6 0.6 1.6e-05 25.1 0.0 4.2 1 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGR33522.1 - 1.5e-05 24.1 3.9 0.19 10.7 0.0 3.1 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGR33522.1 - 0.00041 19.1 1.9 0.46 9.1 1.4 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 HPS3_N PF14761.6 EGR33522.1 - 0.25 10.9 3.2 0.94 9.0 1.1 2.5 1 1 1 3 3 3 0 Hermansky-Pudlak syndrome 3 PhoLip_ATPase_C PF16212.5 EGR33523.1 - 1.1e-59 202.3 26.7 1.1e-59 202.3 26.7 3.0 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGR33523.1 - 1.2e-23 82.5 2.4 1.2e-23 82.5 2.4 2.9 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGR33523.1 - 3.7e-12 46.2 0.1 1.1e-10 41.5 0.0 2.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGR33523.1 - 6.3e-12 46.2 0.2 1.7e-05 25.2 0.1 3.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGR33523.1 - 3.3e-07 30.0 0.0 8.5e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGR33523.1 - 2.8e-06 27.3 1.2 2.8e-06 27.3 1.2 4.7 4 1 1 6 6 6 1 haloacid dehalogenase-like hydrolase DUF4459 PF14673.6 EGR33523.1 - 0.027 14.4 0.0 0.094 12.6 0.0 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) RCC1 PF00415.18 EGR33524.1 - 2.5e-18 66.4 8.3 4.6e-08 33.6 0.1 5.5 4 3 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR33524.1 - 7.1e-17 60.7 12.6 1.5e-06 27.9 0.0 5.9 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat LAMTOR PF15454.6 EGR33524.1 - 0.0068 17.0 1.8 0.57 10.8 0.0 2.9 3 0 0 3 3 3 1 Late endosomal/lysosomal adaptor and MAPK and MTOR activator Laminin_G_1 PF00054.23 EGR33524.1 - 0.12 12.6 0.0 0.81 9.9 0.0 2.3 2 1 0 2 2 2 0 Laminin G domain WD40 PF00400.32 EGR33525.1 - 8.6e-19 67.5 8.6 0.0039 18.0 0.0 7.5 8 0 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR33525.1 - 7.9e-06 26.1 0.6 2.3 8.6 0.0 4.6 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain EF-hand_1 PF00036.32 EGR33525.1 - 0.00011 21.5 0.9 0.00048 19.5 0.2 2.4 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EGR33525.1 - 0.00031 20.4 0.6 0.0012 18.7 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EGR33525.1 - 0.00033 21.0 2.7 0.00094 19.6 2.7 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGR33525.1 - 0.00047 19.5 0.4 0.0013 18.1 0.4 1.8 1 0 0 1 1 1 1 EF hand Ge1_WD40 PF16529.5 EGR33525.1 - 0.0014 17.7 0.5 0.85 8.5 0.0 3.0 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PQQ PF01011.21 EGR33525.1 - 0.084 12.8 0.0 0.72 9.9 0.0 2.5 3 0 0 3 3 3 0 PQQ enzyme repeat Phosphorylase PF00343.20 EGR33526.1 - 2.1e-253 842.8 0.3 2.5e-253 842.5 0.3 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase Q_salvage PF10343.9 EGR33530.1 - 2.4e-74 250.5 15.5 2e-63 214.6 3.5 2.4 3 0 0 3 3 3 2 Potential Queuosine, Q, salvage protein family DUF1688 PF07958.11 EGR33530.1 - 0.018 13.8 0.4 0.093 11.4 0.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF1688) TB2_DP1_HVA22 PF03134.19 EGR33531.1 - 9.5e-28 95.9 7.9 9.5e-28 95.9 7.9 2.0 2 0 0 2 2 2 1 TB2/DP1, HVA22 family DUF2304 PF10066.9 EGR33531.1 - 0.009 16.2 7.5 0.77 10.0 0.7 2.8 3 0 0 3 3 3 2 Uncharacterized conserved protein (DUF2304) ECF_trnsprt PF12822.7 EGR33531.1 - 0.016 15.3 1.1 0.022 14.9 0.2 1.5 1 1 0 1 1 1 0 ECF transporter, substrate-specific component MT0933_antitox PF14013.6 EGR33531.1 - 0.19 12.1 0.1 4 7.8 0.0 2.2 2 0 0 2 2 2 0 MT0933-like antitoxin protein TTL PF03133.15 EGR33532.1 - 2.1e-82 276.6 11.2 2.7e-82 276.2 11.2 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR33532.1 - 9.9e-09 34.8 8.9 0.0007 18.9 0.0 4.0 2 2 2 4 4 4 3 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR33532.1 - 6.1e-07 29.0 0.0 0.0037 16.5 0.0 2.6 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp RimK PF08443.11 EGR33532.1 - 3.8e-05 23.4 0.2 0.0092 15.6 0.1 2.3 2 0 0 2 2 2 2 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 EGR33532.1 - 0.0022 18.1 0.0 0.012 15.7 0.1 2.0 2 0 0 2 2 2 1 ATP-grasp domain PseudoU_synth_1 PF01416.20 EGR33533.1 - 1.7e-31 108.8 0.0 2.2e-31 108.5 0.0 1.1 1 0 0 1 1 1 1 tRNA pseudouridine synthase DUF1933 PF09147.10 EGR33533.1 - 0.043 13.4 0.1 0.057 13.0 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) Pkinase PF00069.25 EGR33534.1 - 1.8e-25 89.8 2.4 1.6e-22 80.2 0.1 3.4 3 1 1 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33534.1 - 2.2e-09 37.0 4.2 0.00089 18.6 0.5 3.7 1 1 1 2 2 2 2 Protein tyrosine kinase EF-hand_1 PF00036.32 EGR33535.1 - 7.9e-28 93.9 45.1 0.0012 18.3 0.1 12.6 11 0 0 11 11 11 9 EF hand EF-hand_7 PF13499.6 EGR33535.1 - 9e-25 86.9 51.4 4.6e-06 27.0 0.4 12.8 11 4 1 12 12 12 6 EF-hand domain pair EF-hand_6 PF13405.6 EGR33535.1 - 4.6e-21 72.9 49.1 0.0021 17.8 1.5 13.6 14 1 1 15 15 15 8 EF-hand domain EF-hand_8 PF13833.6 EGR33535.1 - 2.1e-17 62.7 38.7 2.3e-10 40.2 0.3 9.5 10 0 0 10 10 10 5 EF-hand domain pair EF-hand_5 PF13202.6 EGR33535.1 - 2.8e-13 48.7 29.5 0.0036 16.7 0.1 9.2 8 0 0 8 8 8 6 EF hand WD40 PF00400.32 EGR33535.1 - 0.001 19.8 0.1 1.1 10.2 0.0 2.8 2 0 0 2 2 2 2 WD domain, G-beta repeat EF-hand_9 PF14658.6 EGR33535.1 - 0.006 16.9 0.0 4.4 7.7 0.0 4.5 4 0 0 4 4 4 1 EF-hand domain Malic_M PF03949.15 EGR33535.1 - 0.14 11.4 0.4 0.35 10.1 0.4 1.6 1 0 0 1 1 1 0 Malic enzyme, NAD binding domain Ion_trans PF00520.31 EGR33537.1 - 1.1e-84 283.5 124.8 5.5e-33 114.2 29.8 5.6 4 1 0 4 4 4 4 Ion transport protein Pkinase PF00069.25 EGR33538.1 - 6.6e-46 156.8 0.1 3.8e-45 154.3 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Cyclin_N PF00134.23 EGR33538.1 - 1.3e-28 99.3 10.7 6.4e-25 87.4 4.2 2.7 2 0 0 2 2 2 2 Cyclin, N-terminal domain Pkinase_Tyr PF07714.17 EGR33538.1 - 2.4e-23 82.7 0.1 6.9e-23 81.3 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Cyclin_C PF02984.19 EGR33538.1 - 2.5e-09 37.3 3.3 3.2e-09 36.9 0.6 2.6 3 0 0 3 3 3 1 Cyclin, C-terminal domain F-box-like PF12937.7 EGR33538.1 - 3e-05 23.8 0.0 0.00036 20.4 0.0 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGR33538.1 - 0.016 15.1 0.0 0.047 13.6 0.0 1.8 1 0 0 1 1 1 0 F-box domain XS PF03468.14 EGR33538.1 - 0.13 12.6 1.1 0.43 10.9 1.1 1.9 1 0 0 1 1 1 0 XS domain MORN PF02493.20 EGR33539.1 - 5.5e-09 35.4 4.0 0.00077 19.2 0.2 3.0 3 0 0 3 3 3 2 MORN repeat DUF3211 PF11485.8 EGR33539.1 - 0.38 11.0 5.7 0.078 13.2 1.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3211) Myb_DNA-binding PF00249.31 EGR33540.1 - 1.5e-26 92.3 6.8 3e-17 62.5 0.4 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGR33540.1 - 1.1e-18 67.2 15.2 4.2e-16 59.0 2.1 3.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain HTH_AsnC-type PF13404.6 EGR33540.1 - 0.055 13.3 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain HTH_32 PF13565.6 EGR33540.1 - 0.056 14.1 0.2 0.17 12.6 0.2 1.8 1 0 0 1 1 1 0 Homeodomain-like domain DED PF01335.21 EGR33540.1 - 0.29 11.5 7.6 0.24 11.7 1.0 2.9 3 1 0 3 3 3 0 Death effector domain Nup160 PF11715.8 EGR33541.1 - 1.4e-08 33.9 3.1 0.00038 19.3 0.1 2.9 2 1 1 3 3 3 2 Nucleoporin Nup120/160 zf-B_box PF00643.24 EGR33541.1 - 0.1 12.7 4.8 0.25 11.6 4.8 1.6 1 0 0 1 1 1 0 B-box zinc finger Cyclin_C_2 PF16899.5 EGR33541.1 - 0.15 12.5 4.4 1.2 9.5 0.1 2.9 1 1 1 2 2 2 0 Cyclin C-terminal domain Ank_5 PF13857.6 EGR33542.1 - 2.4e-16 59.6 0.3 2.2e-09 37.4 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGR33542.1 - 2.4e-13 50.3 0.4 8.4e-07 29.4 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGR33542.1 - 3.9e-11 43.4 4.1 1.1e-09 38.7 0.6 2.0 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGR33542.1 - 1e-09 38.4 0.1 0.0024 18.3 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EGR33542.1 - 1.3e-08 34.4 0.1 5.3e-05 23.3 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat DUF3447 PF11929.8 EGR33542.1 - 0.04 13.9 8.0 0.14 12.1 0.4 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) Pkinase PF00069.25 EGR33543.1 - 3.3e-39 134.8 0.0 4e-39 134.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33543.1 - 4.9e-29 101.4 0.0 5.5e-29 101.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33543.1 - 0.00023 20.6 0.0 0.00029 20.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 EGR33543.1 - 0.033 13.2 0.2 0.04 12.9 0.1 1.5 1 1 0 1 1 1 0 Poxvirus serine/threonine protein kinase DUF3447 PF11929.8 EGR33543.1 - 0.066 13.2 0.2 0.19 11.7 0.1 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF3447) eIF2A PF08662.11 EGR33544.1 - 5.9e-61 205.7 0.3 5e-59 199.5 0.1 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Oxysterol_BP PF01237.18 EGR33546.1 - 2.4e-50 171.5 1.3 2.8e-42 144.9 0.0 2.0 1 1 0 2 2 2 2 Oxysterol-binding protein PBP1_TM PF14812.6 EGR33547.1 - 1.6 9.1 11.1 3.2 8.2 2.3 2.1 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4666 PF15697.5 EGR33547.1 - 2.7 8.7 7.4 2.1 9.1 1.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) Presenilin PF01080.17 EGR33547.1 - 8.7 5.0 7.8 11 4.6 7.8 1.1 1 0 0 1 1 1 0 Presenilin MIF4G PF02854.19 EGR33548.1 - 9.1e-38 130.0 63.2 6.3e-17 61.9 13.6 4.7 3 2 1 4 4 4 3 MIF4G domain Peptidase_M8 PF01457.16 EGR33551.1 - 4.2e-32 111.5 0.0 5.5e-32 111.1 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin IF-2B PF01008.17 EGR33552.1 - 1.7e-11 43.9 0.2 1.9e-11 43.7 0.2 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family Lipoprotein_2 PF00921.17 EGR33552.1 - 0.089 12.3 1.1 0.11 12.0 0.2 1.5 2 0 0 2 2 2 0 Borrelia lipoprotein ATP12 PF07542.11 EGR33552.1 - 0.099 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 ATP12 chaperone protein KIX_2 PF16987.5 EGR33552.1 - 0.46 10.5 5.5 4.1 7.5 0.1 2.9 2 1 1 3 3 3 0 KIX domain ABC_membrane_2 PF06472.15 EGR33553.1 - 1.6e-73 247.4 11.0 5.7e-70 235.8 2.5 2.2 1 1 1 2 2 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EGR33553.1 - 3.2e-16 60.1 0.0 4.3e-15 56.4 0.0 2.6 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 EGR33553.1 - 0.00016 21.6 0.1 0.00089 19.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGR33553.1 - 0.00073 19.0 0.5 0.074 12.5 0.1 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGR33553.1 - 0.0055 17.2 0.6 0.013 16.0 0.1 1.9 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 EGR33553.1 - 0.013 15.2 4.0 0.29 10.8 0.1 2.3 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EGR33553.1 - 0.045 13.5 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain STI1 PF17830.1 EGR33553.1 - 0.073 13.0 0.1 0.74 9.8 0.0 2.6 3 0 0 3 3 3 0 STI1 domain ORMDL PF04061.14 EGR33554.1 - 0.13 12.0 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 ORMDL family EF-hand_1 PF00036.32 EGR33555.1 - 2.8e-07 29.6 1.1 5.8e-06 25.5 0.1 2.6 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 EGR33555.1 - 4e-07 30.4 1.7 0.0015 19.0 0.2 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGR33555.1 - 1.4e-05 24.4 2.7 2.7e-05 23.5 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EGR33555.1 - 1.4e-05 24.8 1.9 4.1e-05 23.4 0.1 2.4 1 1 2 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.6 EGR33555.1 - 1.5e-05 24.5 0.2 0.0011 18.7 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain RPAP1_N PF08621.10 EGR33555.1 - 0.056 13.2 1.0 0.079 12.7 1.0 1.2 1 0 0 1 1 1 0 RPAP1-like, N-terminal ATP-grasp_2 PF08442.10 EGR33556.1 - 6.5e-45 153.2 0.2 1e-44 152.6 0.2 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 EGR33556.1 - 1e-15 57.9 0.8 1.5e-15 57.3 0.2 1.6 2 0 0 2 2 2 1 CoA-ligase ECSIT PF06239.11 EGR33556.1 - 0.38 9.8 3.7 0.26 10.4 1.6 1.8 2 0 0 2 2 2 0 Evolutionarily conserved signalling intermediate in Toll pathway Cyclin_N PF00134.23 EGR33558.1 - 2.8e-12 46.5 0.6 2.8e-12 46.5 0.6 1.7 2 1 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGR33558.1 - 0.0052 16.9 0.2 0.011 15.9 0.2 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain DUF3925 PF13063.6 EGR33558.1 - 7.5 6.8 10.3 1.3 9.3 1.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3925) CK_II_beta PF01214.18 EGR33559.1 - 1e-69 234.0 1.1 2.4e-69 232.8 0.0 1.8 2 0 0 2 2 2 1 Casein kinase II regulatory subunit GP24_25 PF17388.2 EGR33559.1 - 0.23 11.4 0.9 1.3 9.0 0.0 2.2 2 1 0 2 2 2 0 Tail assembly gene products 24 & 25 Kinesin PF00225.23 EGR33560.1 - 1.3e-87 293.9 7.1 2.4e-87 293.0 7.1 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR33560.1 - 2e-17 63.5 0.3 2e-17 63.5 0.3 3.0 3 1 0 3 3 3 1 Microtubule binding AAA_22 PF13401.6 EGR33560.1 - 0.18 12.1 3.2 1.7 8.9 0.0 3.0 3 1 0 3 3 3 0 AAA domain MIR PF02815.19 EGR33561.1 - 1.2e-13 51.3 1.6 1.2e-13 51.3 1.6 3.5 4 0 0 4 4 4 1 MIR domain Ins145_P3_rec PF08709.11 EGR33561.1 - 6.3e-06 25.5 9.3 2e-05 23.9 3.9 2.9 2 1 0 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor CAP_GLY PF01302.25 EGR33564.1 - 9.4e-20 70.4 1.0 1.5e-19 69.8 1.0 1.3 1 0 0 1 1 1 1 CAP-Gly domain DivIC PF04977.15 EGR33564.1 - 0.0064 16.2 3.2 0.0064 16.2 3.2 9.1 5 2 5 10 10 10 4 Septum formation initiator Med9 PF07544.13 EGR33564.1 - 0.012 15.6 6.2 0.012 15.6 6.2 7.5 4 2 3 7 7 7 0 RNA polymerase II transcription mediator complex subunit 9 HHH_3 PF12836.7 EGR33564.1 - 1.1 9.6 8.6 0.11 12.8 1.7 3.1 3 0 0 3 3 3 0 Helix-hairpin-helix motif TFIIS_C PF01096.18 EGR33565.1 - 2.8e-17 62.3 4.5 2.8e-17 62.3 4.5 2.9 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Peptidase_S15 PF02129.18 EGR33565.1 - 0.00022 20.9 0.0 0.00059 19.5 0.0 1.6 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) RNA_POL_M_15KD PF02150.16 EGR33565.1 - 0.0024 17.7 11.4 0.43 10.5 1.7 3.7 3 0 0 3 3 3 2 RNA polymerases M/15 Kd subunit Zn_Tnp_IS1595 PF12760.7 EGR33565.1 - 0.0024 17.8 8.1 0.031 14.2 1.6 2.6 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Ribosomal_S27 PF01599.19 EGR33565.1 - 0.0031 17.6 1.4 0.27 11.4 0.1 2.8 2 0 0 2 2 2 1 Ribosomal protein S27a Hydrolase_4 PF12146.8 EGR33565.1 - 0.0035 16.6 0.0 0.64 9.2 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 OrfB_Zn_ribbon PF07282.11 EGR33565.1 - 0.023 14.6 0.8 0.023 14.6 0.8 2.8 2 1 0 2 2 2 0 Putative transposase DNA-binding domain IBR PF01485.21 EGR33565.1 - 0.025 14.8 9.5 0.12 12.7 1.4 2.8 2 0 0 2 2 2 0 IBR domain, a half RING-finger domain Abhydrolase_4 PF08386.10 EGR33565.1 - 0.034 14.3 0.0 0.063 13.4 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.13 EGR33565.1 - 0.059 13.0 0.0 0.41 10.3 0.0 2.1 1 1 1 2 2 2 0 Serine hydrolase (FSH1) TF_Zn_Ribbon PF08271.12 EGR33565.1 - 0.073 12.6 0.1 0.073 12.6 0.1 3.5 3 1 1 4 4 4 0 TFIIB zinc-binding Ogr_Delta PF04606.12 EGR33565.1 - 0.35 10.9 9.9 0.072 13.1 3.5 2.6 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger DZR PF12773.7 EGR33565.1 - 4 7.5 14.5 1.5 8.9 3.5 3.1 2 1 1 3 3 3 0 Double zinc ribbon UPF0547 PF10571.9 EGR33565.1 - 5 7.3 13.4 0.67 10.1 0.2 3.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-C2H2_3 PF13878.6 EGR33565.1 - 7.6 6.5 14.5 16 5.4 0.4 4.2 4 0 0 4 4 4 0 zinc-finger of acetyl-transferase ESCO Zn-ribbon_8 PF09723.10 EGR33565.1 - 8.6 6.6 17.2 26 5.0 0.1 4.8 4 1 0 4 4 4 0 Zinc ribbon domain VSP PF03302.13 EGR33566.1 - 2.2e-09 36.7 185.7 0.00011 21.2 16.5 9.3 1 1 6 8 8 8 7 Giardia variant-specific surface protein GF_recep_IV PF14843.6 EGR33566.1 - 0.00013 21.8 222.2 0.01 15.7 27.7 9.7 2 1 7 9 9 9 3 Growth factor receptor domain IV Binary_toxB PF03495.14 EGR33566.1 - 0.072 13.3 0.0 9 6.6 0.0 3.1 2 1 0 2 2 2 0 Clostridial binary toxin B/anthrax toxin PA Ca-binding domain Methyltransf_11 PF08241.12 EGR33567.1 - 3.2e-14 53.3 0.0 5e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGR33567.1 - 2e-13 50.4 0.3 2.5e-13 50.1 0.3 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGR33567.1 - 2e-12 47.7 0.0 4.1e-12 46.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGR33567.1 - 4.1e-06 26.3 0.1 4.9e-06 26.1 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGR33567.1 - 1.1e-05 26.0 0.1 2.6e-05 24.9 0.1 1.7 2 0 0 2 2 2 1 Methyltransferase domain RIF5_SNase_2 PF18189.1 EGR33567.1 - 0.16 11.8 0.0 0.3 10.9 0.0 1.4 1 1 0 1 1 1 0 TbRIF5 SNase domain 2 adh_short PF00106.25 EGR33567.1 - 0.17 11.3 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase AAA PF00004.29 EGR33568.1 - 3.8e-43 147.1 0.0 6.9e-43 146.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGR33568.1 - 3.9e-11 42.6 0.1 7.4e-11 41.7 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGR33568.1 - 1.1e-07 32.0 0.1 4.2e-07 30.0 0.0 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 EGR33568.1 - 3.1e-07 30.2 1.3 4.3e-07 29.8 0.3 1.8 2 0 0 2 2 1 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 EGR33568.1 - 1.4e-06 28.8 0.0 0.00015 22.2 0.0 2.9 2 1 0 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 EGR33568.1 - 1.1e-05 25.6 0.1 4.2e-05 23.7 0.0 2.0 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGR33568.1 - 1.2e-05 25.7 0.6 0.0088 16.3 0.2 2.7 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.12 EGR33568.1 - 4.4e-05 23.3 0.0 9.4e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGR33568.1 - 0.00044 19.6 0.0 0.0011 18.3 0.0 1.7 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 EGR33568.1 - 0.0013 18.5 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 EGR33568.1 - 0.0022 18.2 0.0 0.0054 16.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGR33568.1 - 0.0034 16.9 0.0 0.0072 15.9 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 EGR33568.1 - 0.0043 17.6 0.3 0.018 15.6 0.0 2.2 3 0 0 3 3 2 1 AAA domain Parvo_NS1 PF01057.17 EGR33568.1 - 0.0048 16.0 0.0 0.0088 15.2 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.21 EGR33568.1 - 0.0054 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGR33568.1 - 0.0065 16.3 0.0 0.015 15.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EGR33568.1 - 0.0078 16.5 0.0 0.016 15.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 EGR33568.1 - 0.0079 15.6 0.1 0.028 13.8 0.0 1.9 2 0 0 2 2 2 1 KaiC TsaE PF02367.17 EGR33568.1 - 0.0087 16.1 0.0 0.018 15.1 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Filament PF00038.21 EGR33568.1 - 0.015 14.9 0.4 0.015 14.9 0.4 1.6 2 0 0 2 2 1 0 Intermediate filament protein AAA_24 PF13479.6 EGR33568.1 - 0.015 15.0 0.0 0.073 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGR33568.1 - 0.017 14.7 0.1 0.15 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 EGR33568.1 - 0.017 14.8 0.1 0.063 13.0 0.0 1.9 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_14 PF13173.6 EGR33568.1 - 0.018 15.1 0.0 0.044 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGR33568.1 - 0.021 15.2 0.0 0.046 14.1 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_17 PF13207.6 EGR33568.1 - 0.023 15.1 0.0 0.29 11.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EGR33568.1 - 0.024 14.1 0.1 0.15 11.5 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein ABC_tran PF00005.27 EGR33568.1 - 0.035 14.6 0.2 0.32 11.5 0.0 2.5 3 0 0 3 3 3 0 ABC transporter NACHT PF05729.12 EGR33568.1 - 0.069 13.1 0.0 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_11 PF13086.6 EGR33568.1 - 0.07 12.9 0.4 0.34 10.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EGR33568.1 - 0.086 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_19 PF13245.6 EGR33568.1 - 0.11 12.9 0.2 0.31 11.4 0.1 1.7 1 1 0 1 1 1 0 AAA domain Peptidase_C1 PF00112.23 EGR33569.1 - 1e-08 35.5 0.6 1.3e-08 35.2 0.6 1.0 1 0 0 1 1 1 1 Papain family cysteine protease PUF PF00806.19 EGR33570.1 - 1e-39 132.0 33.0 7.3e-08 31.7 0.1 8.2 8 0 0 8 8 8 6 Pumilio-family RNA binding repeat CPL PF08144.11 EGR33570.1 - 0.0052 17.2 4.0 1.7 8.9 0.1 3.9 2 1 3 5 5 5 2 CPL (NUC119) domain CENP_C_N PF15622.6 EGR33570.1 - 0.022 14.2 0.2 0.044 13.2 0.2 1.4 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal ParE_toxin PF05016.15 EGR33570.1 - 0.035 14.7 0.2 0.21 12.2 0.1 2.2 2 0 0 2 2 2 0 ParE toxin of type II toxin-antitoxin system, parDE Zemlya PF17646.1 EGR33570.1 - 0.17 12.3 3.5 2.1 8.7 0.1 2.9 2 1 1 3 3 3 0 Closterovirus 1a polyprotein central region HIP1_clath_bdg PF16515.5 EGR33571.1 - 1.3 9.7 6.1 0.26 11.9 2.4 1.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Aminotran_1_2 PF00155.21 EGR33572.1 - 6e-85 285.6 0.0 6.9e-85 285.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II DSPc PF00782.20 EGR33573.1 - 4.8e-19 68.5 0.1 9.1e-19 67.6 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGR33573.1 - 0.00085 18.9 0.0 0.0014 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGR33573.1 - 0.018 15.2 0.0 0.05 13.7 0.0 1.6 1 1 0 1 1 1 0 Inositol hexakisphosphate ANAPC4_WD40 PF12894.7 EGR33574.1 - 8e-16 58.1 3.3 0.0039 17.5 0.0 6.8 4 1 2 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGR33574.1 - 8.9e-16 58.0 2.1 0.012 16.5 0.0 8.1 9 0 0 9 9 9 3 WD domain, G-beta repeat EF-hand_7 PF13499.6 EGR33574.1 - 0.079 13.4 0.2 0.42 11.1 0.1 2.4 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 EGR33574.1 - 0.11 12.2 0.2 0.51 10.0 0.2 2.2 1 0 0 1 1 1 0 EF hand Archease PF01951.16 EGR33574.1 - 0.15 12.3 3.2 0.34 11.1 0.1 3.2 3 1 0 3 3 3 0 Archease protein family (MTH1598/TM1083) Nrf1_activ_bdg PF10492.9 EGR33574.1 - 7.5 7.3 9.0 2.4 8.9 1.3 3.4 3 0 0 3 3 3 0 Nrf1 activator activation site binding domain SHIPPO-rpt PF07004.12 EGR33575.1 - 0.0062 17.4 11.1 0.73 10.9 0.2 3.5 3 0 0 3 3 3 2 Sperm-tail PG-rich repeat TIP41 PF04176.13 EGR33576.1 - 2.7e-36 124.6 3.3 5e-36 123.8 3.3 1.5 1 0 0 1 1 1 1 TIP41-like family ATP-synt_C PF00137.21 EGR33577.1 - 1.5e-33 114.9 36.9 8.5e-21 74.1 14.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C GerA PF03323.13 EGR33577.1 - 0.26 9.7 4.8 5.1 5.4 1.7 2.2 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein GHMP_kinases_C PF08544.13 EGR33578.1 - 4e-05 23.9 0.0 6.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 GHMP kinases C terminal Beach PF02138.18 EGR33579.1 - 5.2e-110 367.2 1.0 9.3e-110 366.3 1.0 1.4 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EGR33579.1 - 5e-11 42.6 4.5 3.4e-07 30.3 0.4 3.9 2 1 0 2 2 2 2 PH domain associated with Beige/BEACH GRAM PF02893.20 EGR33579.1 - 1.5e-07 31.3 1.7 1.4e-05 24.9 0.2 2.8 2 0 0 2 2 2 1 GRAM domain ANAPC4_WD40 PF12894.7 EGR33579.1 - 1.6e-06 28.3 2.7 0.029 14.7 0.1 4.0 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGR33579.1 - 0.00039 21.2 4.5 0.53 11.3 0.2 4.9 5 0 0 5 5 5 1 WD domain, G-beta repeat PH_TFIIH PF08567.11 EGR33579.1 - 0.095 13.0 0.0 0.53 10.6 0.0 2.3 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain PH PF00169.29 EGR33579.1 - 0.95 10.0 4.2 0.94 10.0 0.1 2.9 2 1 1 3 3 3 0 PH domain NAC PF01849.18 EGR33580.1 - 8.8e-21 73.6 0.6 1.7e-20 72.7 0.6 1.5 1 0 0 1 1 1 1 NAC domain Malate_synthase PF01274.22 EGR33580.1 - 0.044 12.1 0.4 0.05 11.9 0.4 1.1 1 0 0 1 1 1 0 Malate synthase Pkinase PF00069.25 EGR33581.1 - 3.2e-61 207.0 0.3 4.1e-61 206.7 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain MORN PF02493.20 EGR33581.1 - 2.8e-54 177.9 65.1 7.9e-07 28.6 0.8 10.6 10 0 0 10 10 10 9 MORN repeat Pkinase_Tyr PF07714.17 EGR33581.1 - 8.8e-46 156.3 0.0 1.3e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR33581.1 - 2.6e-05 23.2 0.0 4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGR33581.1 - 2.7e-05 23.3 1.0 4.1e-05 22.7 1.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EGR33581.1 - 0.00026 20.2 0.4 0.00055 19.1 0.3 1.6 1 1 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 EGR33581.1 - 0.00031 20.2 0.0 0.00048 19.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like KIND PF16474.5 EGR33581.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.5 1 0 0 1 1 1 0 Kinase non-catalytic C-lobe domain Cyclin_N PF00134.23 EGR33582.1 - 2.9e-37 127.3 3.9 1.5e-35 121.7 1.5 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGR33582.1 - 2.8e-21 75.8 0.2 7.1e-21 74.5 0.2 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ribosom_S12_S23 PF00164.25 EGR33584.1 - 9.5e-46 154.1 0.1 1.2e-45 153.8 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 Myotub-related PF06602.14 EGR33585.1 - 2.1e-121 405.2 8.4 2.9e-121 404.7 8.4 1.2 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 EGR33585.1 - 0.00043 20.2 2.6 0.00044 20.1 0.4 2.1 2 0 0 2 2 2 1 GRAM domain DSPc PF00782.20 EGR33585.1 - 0.012 15.4 0.1 0.048 13.5 0.1 2.0 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGR33585.1 - 0.045 13.7 0.0 0.083 12.8 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family cNMP_binding PF00027.29 EGR33586.1 - 1.9e-12 47.1 0.1 3.1e-12 46.4 0.1 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGR33586.1 - 1.4e-07 31.4 1.6 2.8e-07 30.4 1.6 1.5 1 0 0 1 1 1 1 Ion channel zf-CCHC_4 PF14392.6 EGR33586.1 - 0.018 14.8 0.4 0.038 13.7 0.4 1.6 1 0 0 1 1 1 0 Zinc knuckle PLDc PF00614.22 EGR33587.1 - 1.5e-17 63.0 1.6 7.8e-08 32.2 0.1 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EGR33587.1 - 4.3e-13 49.3 7.3 6.1e-07 29.4 3.2 4.0 2 1 0 2 2 2 2 PLD-like domain RFX_DNA_binding PF02257.15 EGR33587.1 - 0.89 10.2 5.8 27 5.5 0.2 3.7 3 0 0 3 3 3 0 RFX DNA-binding domain Rhodanese PF00581.20 EGR33588.1 - 2.5e-15 56.9 0.0 9.9e-10 38.9 0.0 2.9 3 0 0 3 3 3 2 Rhodanese-like domain Lactamase_B PF00753.27 EGR33588.1 - 1.3e-09 38.3 0.0 2.4e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily ANF_receptor PF01094.28 EGR33588.1 - 0.055 12.6 0.0 0.077 12.1 0.0 1.2 1 0 0 1 1 1 0 Receptor family ligand binding region Lactamase_B_2 PF12706.7 EGR33588.1 - 0.15 11.5 0.0 0.27 10.7 0.0 1.5 1 0 0 1 1 1 0 Beta-lactamase superfamily domain PMSI1 PF15322.6 EGR33590.1 - 2.4 7.5 4.5 2.7 7.3 4.5 1.1 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative RNase_HII PF01351.18 EGR33590.1 - 2.8 7.7 8.9 1.3 8.8 6.3 1.6 1 1 0 1 1 1 0 Ribonuclease HII ARHGEF5_35 PF15441.6 EGR33590.1 - 4.3 6.2 12.2 4.7 6.1 12.2 1.1 1 0 0 1 1 1 0 Rho guanine nucleotide exchange factor 5/35 DUF5340 PF17275.2 EGR33590.1 - 9.6 6.4 12.7 1.5 9.0 1.3 2.4 1 1 1 2 2 2 0 Family of unknown function (DUF5340) ABC_tran PF00005.27 EGR33591.1 - 3.7e-29 102.0 0.1 4.4e-29 101.7 0.1 1.1 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGR33591.1 - 4.5e-05 23.0 0.7 0.027 13.9 0.1 2.1 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGR33591.1 - 5.6e-05 23.1 0.3 0.0081 16.0 0.1 2.1 1 1 1 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EGR33591.1 - 0.00034 20.9 0.3 0.0024 18.1 0.3 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 EGR33591.1 - 0.00078 19.5 0.2 0.0019 18.3 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 EGR33591.1 - 0.0053 16.5 0.2 1.4 8.6 0.0 2.0 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EGR33591.1 - 0.0086 15.8 0.8 0.023 14.4 0.8 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGR33591.1 - 0.015 15.7 0.1 0.023 15.1 0.1 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_7 PF12775.7 EGR33591.1 - 0.017 14.6 0.1 0.058 12.9 0.0 1.8 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF87 PF01935.17 EGR33591.1 - 0.033 14.3 0.6 0.11 12.5 0.0 1.9 2 1 0 2 2 2 0 Helicase HerA, central domain AAA_23 PF13476.6 EGR33591.1 - 0.035 14.6 1.6 0.11 13.0 1.5 1.8 1 1 0 1 1 1 0 AAA domain DUF5507 PF17612.2 EGR33591.1 - 0.041 13.6 0.1 0.064 13.0 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5507) DEAD PF00270.29 EGR33591.1 - 0.045 13.5 2.3 0.45 10.3 2.3 2.0 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_29 PF13555.6 EGR33591.1 - 0.058 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain CSTF2_hinge PF14327.6 EGR33591.1 - 0.072 13.5 0.3 1.1 9.7 0.3 2.2 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 Viral_helicase1 PF01443.18 EGR33591.1 - 0.072 12.8 0.1 1.9 8.2 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 EGR33591.1 - 0.074 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase Dynamin_N PF00350.23 EGR33591.1 - 0.13 12.3 0.7 0.29 11.2 0.7 1.9 1 1 0 1 1 1 0 Dynamin family AAA_7 PF12775.7 EGR33592.1 - 1.5e-24 86.5 0.0 2.1e-24 86.1 0.0 1.2 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_6 PF12774.7 EGR33593.1 - 3.9e-148 492.8 0.0 1.9e-147 490.5 0.0 2.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGR33593.1 - 1.8e-108 363.2 31.7 1.8e-108 363.2 31.7 4.5 5 1 0 5 5 5 1 Dynein heavy chain, N-terminal region 2 AAA_5 PF07728.14 EGR33593.1 - 0.00061 19.8 0.1 0.36 10.8 0.0 4.1 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EGR33593.1 - 0.042 14.3 0.0 0.042 14.3 0.0 4.4 5 0 0 5 5 5 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGR33593.1 - 0.43 11.1 0.0 0.43 11.1 0.0 4.3 5 1 0 5 5 5 0 AAA domain AAA_11 PF13086.6 EGR33594.1 - 6.3e-58 196.6 0.9 1.9e-57 195.0 0.9 1.9 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 EGR33594.1 - 3.2e-16 59.6 0.3 1e-15 57.9 0.3 1.8 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGR33594.1 - 8.8e-11 41.9 0.0 3.7e-09 36.6 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGR33594.1 - 1.5e-08 35.1 0.1 1e-07 32.4 0.0 2.4 2 1 0 2 2 2 1 AAA domain Helicase_RecD PF05127.14 EGR33594.1 - 1.4e-05 25.0 0.6 0.029 14.2 0.0 3.0 1 1 1 2 2 2 2 Helicase AAA PF00004.29 EGR33594.1 - 5.4e-05 23.6 0.1 0.00021 21.7 0.1 2.1 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 EGR33594.1 - 0.00021 21.3 2.5 0.00048 20.2 0.1 2.8 3 1 0 3 3 2 1 Type III restriction enzyme, res subunit AAA_16 PF13191.6 EGR33594.1 - 0.00037 20.9 0.0 0.00083 19.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 EGR33594.1 - 0.00054 19.1 0.2 0.16 11.0 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein PIF1 PF05970.14 EGR33594.1 - 0.00055 19.2 0.4 0.063 12.4 0.0 2.9 3 0 0 3 3 3 1 PIF1-like helicase IstB_IS21 PF01695.17 EGR33594.1 - 0.0012 18.6 0.0 0.0012 18.6 0.0 3.1 4 1 1 5 5 5 1 IstB-like ATP binding protein DEAD PF00270.29 EGR33594.1 - 0.0031 17.3 3.4 0.098 12.4 0.9 3.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGR33594.1 - 0.0033 17.7 1.7 0.018 15.3 0.2 3.0 3 1 0 3 3 2 1 AAA domain PhoH PF02562.16 EGR33594.1 - 0.0086 15.6 0.3 0.084 12.3 0.0 2.5 3 0 0 3 3 3 1 PhoH-like protein cobW PF02492.19 EGR33594.1 - 0.035 13.7 0.6 0.2 11.2 0.0 2.5 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_23 PF13476.6 EGR33594.1 - 0.051 14.1 0.0 0.051 14.1 0.0 4.2 3 1 1 4 4 3 0 AAA domain Viral_helicase1 PF01443.18 EGR33594.1 - 0.052 13.3 0.9 12 5.5 0.1 2.9 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Zot PF05707.12 EGR33594.1 - 0.057 13.1 0.1 0.33 10.6 0.0 2.3 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) SRP54 PF00448.22 EGR33594.1 - 0.064 12.9 0.1 0.28 10.8 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain RuvB_N PF05496.12 EGR33594.1 - 0.073 12.8 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 EGR33594.1 - 0.073 12.8 0.3 1.7 8.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 EGR33594.1 - 0.08 13.5 0.7 0.5 10.9 0.1 2.7 2 1 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.18 EGR33594.1 - 0.096 12.0 0.0 0.44 9.9 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_28 PF13521.6 EGR33594.1 - 0.12 12.6 0.0 0.35 11.1 0.0 1.8 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.6 EGR33594.1 - 0.25 11.9 2.8 1 9.9 0.2 3.3 2 2 0 2 2 2 0 AAA domain GpcrRhopsn4 PF10192.9 EGR33595.1 - 1.4e-30 106.6 6.8 1.7e-30 106.3 6.8 1.0 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Colicin_V PF02674.16 EGR33595.1 - 0.012 15.6 3.7 0.028 14.4 0.1 2.1 1 1 1 2 2 2 0 Colicin V production protein Guanylate_cyc PF00211.20 EGR33596.1 - 1.9e-11 43.9 0.0 5.4e-11 42.4 0.0 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain OmpH PF03938.14 EGR33596.1 - 0.00047 20.5 18.2 0.001 19.4 18.2 1.5 1 0 0 1 1 1 1 Outer membrane protein (OmpH-like) DDHD PF02862.17 EGR33596.1 - 0.017 15.3 2.0 0.027 14.7 2.0 1.3 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 EGR33596.1 - 0.04 12.7 4.9 0.07 11.9 4.9 1.4 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 EGR33596.1 - 0.097 11.5 8.5 0.15 10.9 8.5 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Sec62 PF03839.16 EGR33596.1 - 0.19 11.2 12.2 0.39 10.2 12.2 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 DUF4407 PF14362.6 EGR33596.1 - 0.2 11.0 8.1 0.36 10.1 8.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) CSG2 PF16965.5 EGR33596.1 - 0.46 9.4 5.0 0.96 8.3 5.0 1.5 1 0 0 1 1 1 0 Ceramide synthase regulator Zip PF02535.22 EGR33596.1 - 0.5 9.5 1.3 0.87 8.7 1.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter LodA_N PF17990.1 EGR33596.1 - 0.87 9.5 11.2 1.5 8.8 11.2 1.3 1 0 0 1 1 1 0 L-Lysine epsilon oxidase N-terminal FAM60A PF15396.6 EGR33596.1 - 7.6 6.5 15.3 12 5.8 15.3 1.2 1 0 0 1 1 1 0 Protein Family FAM60A MatE PF01554.18 EGR33597.1 - 9.1e-39 132.7 35.1 1.9e-22 79.6 10.9 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EGR33597.1 - 4.9e-09 36.4 9.9 4.9e-09 36.4 9.9 3.6 2 1 1 3 3 3 2 Polysaccharide biosynthesis C-terminal domain DUF1279 PF06916.13 EGR33597.1 - 2.2 8.9 6.8 8.6 7.0 0.2 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1279) Connexin PF00029.19 EGR33598.1 - 0.069 12.9 10.7 0.085 12.6 10.7 1.3 1 0 0 1 1 1 0 Connexin Ureide_permease PF07168.11 EGR33598.1 - 0.17 10.6 8.3 0.18 10.5 8.3 1.1 1 0 0 1 1 1 0 Ureide permease DUF3807 PF12720.7 EGR33598.1 - 0.3 11.3 13.9 0.36 11.1 13.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF724 PF05266.14 EGR33598.1 - 4.8 7.0 27.2 0.91 9.3 23.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) EMC1_C PF07774.13 EGR33603.1 - 3.2e-56 190.4 4.1 6.7e-56 189.3 4.1 1.5 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ PF01011.21 EGR33603.1 - 0.16 12.0 0.2 6.5 6.9 0.1 3.0 3 0 0 3 3 3 0 PQQ enzyme repeat ARID PF01388.21 EGR33604.1 - 9.3e-21 74.3 0.1 9.3e-21 74.3 0.1 3.1 4 1 0 4 4 4 1 ARID/BRIGHT DNA binding domain PX PF00787.24 EGR33606.1 - 2.1e-13 50.2 0.2 2.1e-13 50.2 0.2 2.0 2 1 0 2 2 2 1 PX domain CLZ PF16526.5 EGR33606.1 - 0.0075 16.6 27.2 0.076 13.4 4.1 4.2 3 1 1 4 4 4 2 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Jas PF16135.5 EGR33606.1 - 0.087 13.0 0.1 0.22 11.7 0.1 1.6 1 0 0 1 1 1 0 TPL-binding domain in jasmonate signalling AcylCoA_dehyd_C PF12186.8 EGR33606.1 - 0.87 9.7 6.0 4.5 7.4 0.9 2.9 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal KASH_CCD PF14662.6 EGR33606.1 - 3.8 7.3 40.7 14 5.5 40.7 1.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH ADIP PF11559.8 EGR33606.1 - 5.3 7.1 34.1 5.2 7.1 12.3 3.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CENP-F_leu_zip PF10473.9 EGR33606.1 - 7.1 6.7 34.4 15 5.6 16.9 3.2 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3740 PF12548.8 EGR33606.1 - 7.6 7.0 16.7 1.4 9.3 1.3 3.5 1 1 1 2 2 2 0 Sulfatase protein zf-CpG_bind_C PF12269.8 EGR33606.1 - 8.6 6.1 28.2 0.058 13.2 11.9 3.1 2 1 2 4 4 4 0 CpG binding protein zinc finger C terminal domain GBP PF02263.19 EGR33607.1 - 5.4e-60 202.8 1.9 5.4e-60 202.8 1.9 2.1 2 1 0 2 2 2 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 EGR33607.1 - 2.7e-14 53.3 1.7 2.7e-14 53.3 1.7 2.7 2 1 1 3 3 3 1 Guanylate-binding protein, C-terminal domain MMR_HSR1 PF01926.23 EGR33607.1 - 0.015 15.4 0.1 0.085 12.9 0.1 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Clathrin_H_link PF13838.6 EGR33608.1 - 5.7e-21 74.2 1.0 1.2e-20 73.2 0.1 2.1 2 0 0 2 2 2 1 Clathrin-H-link Clathrin PF00637.20 EGR33608.1 - 1.8e-17 63.5 1.6 7.8e-16 58.2 0.4 2.3 2 0 0 2 2 2 2 Region in Clathrin and VPS DUF4781 PF16013.5 EGR33608.1 - 0.067 12.0 0.2 0.12 11.2 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) TPR_12 PF13424.6 EGR33608.1 - 1.1 9.6 4.8 43 4.5 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat Clathrin_propel PF01394.20 EGR33609.1 - 0.033 14.5 0.1 0.095 13.1 0.1 1.9 1 0 0 1 1 1 0 Clathrin propeller repeat Nucleoporin_FG PF13634.6 EGR33610.1 - 3.5e-28 98.3 291.2 4e-09 37.2 48.0 11.4 4 3 9 13 13 13 9 Nucleoporin FG repeat region Nucleoporin2 PF04096.14 EGR33610.1 - 4.6e-11 43.0 1.4 4.6e-11 43.0 1.4 2.6 3 0 0 3 3 3 1 Nucleoporin autopeptidase DUF1851 PF08906.11 EGR33610.1 - 0.2 11.7 2.4 0.22 11.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1851) TPR_6 PF13174.6 EGR33611.1 - 3.4e-14 52.4 11.1 1.6e-05 25.2 0.2 7.2 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGR33611.1 - 3.4e-12 46.1 0.0 0.037 14.8 0.0 6.5 6 1 1 7 7 7 2 Tetratricopeptide repeat SRP72 PF08492.12 EGR33611.1 - 4.6e-12 46.2 8.0 4.6e-12 46.2 8.0 3.2 3 0 0 3 3 2 1 SRP72 RNA-binding domain TPR_19 PF14559.6 EGR33611.1 - 9.7e-10 38.8 14.6 0.0051 17.3 0.4 6.1 3 3 2 5 5 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR33611.1 - 3e-08 33.8 21.1 2.3e-07 31.0 6.1 5.0 4 2 1 5 5 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EGR33611.1 - 5.7e-08 33.3 0.0 0.025 15.2 0.0 4.3 4 0 0 4 4 4 1 Tetratricopeptide repeat SRP_TPR_like PF17004.5 EGR33611.1 - 8.3e-08 32.3 7.0 8.3e-08 32.3 7.0 3.9 3 1 1 4 4 4 1 Putative TPR-like repeat TPR_2 PF07719.17 EGR33611.1 - 8.8e-08 31.7 17.2 0.14 12.3 1.1 5.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGR33611.1 - 2.3e-06 27.2 2.3 0.0047 16.9 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGR33611.1 - 1.5e-05 24.6 19.5 0.0036 17.1 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGR33611.1 - 1.7e-05 24.9 5.0 1.2 9.6 0.1 4.8 3 1 0 3 3 3 2 Tetratricopeptide repeat PPR PF01535.20 EGR33611.1 - 4.6e-05 23.4 4.6 1.1 9.6 0.1 5.4 6 0 0 6 6 5 1 PPR repeat TPR_8 PF13181.6 EGR33611.1 - 0.0001 22.2 18.5 0.051 13.8 0.2 6.2 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGR33611.1 - 0.00015 22.0 13.5 0.19 12.0 2.1 6.1 4 3 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGR33611.1 - 0.00085 19.1 4.9 1.5 8.8 0.1 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 EGR33611.1 - 0.0016 17.7 17.0 0.0052 16.0 2.3 4.5 1 1 3 5 5 5 2 Tetratricopeptide repeat tRNA-Thr_ED PF08915.11 EGR33611.1 - 0.26 11.3 12.3 1.4 9.0 0.7 4.5 2 2 1 4 4 4 0 Archaea-specific editing domain of threonyl-tRNA synthetase RRM_1 PF00076.22 EGR33612.1 - 0.00021 21.0 0.1 0.00025 20.8 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 EGR33614.1 - 3.2e-68 229.9 0.4 4.6e-68 229.4 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33614.1 - 2e-32 112.5 0.2 5.1e-32 111.2 0.2 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33614.1 - 4.9e-06 26.1 0.0 1e-05 25.0 0.0 1.7 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR33614.1 - 0.0035 16.7 0.7 0.007 15.7 0.7 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGR33614.1 - 0.0073 15.9 0.2 0.013 15.1 0.2 1.3 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 EGR33614.1 - 0.014 15.1 1.1 0.062 12.9 0.3 2.3 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGR33614.1 - 0.075 11.8 0.1 0.16 10.7 0.1 1.5 1 0 0 1 1 1 0 Fungal protein kinase Gtr1_RagA PF04670.12 EGR33615.1 - 7e-32 110.6 12.1 1.1e-31 110.0 12.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGR33615.1 - 5e-07 29.8 0.1 1.3e-06 28.5 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGR33615.1 - 1.3e-05 24.7 0.1 2.6e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit tRNA-synt_1e PF01406.19 EGR33616.1 - 2e-87 293.3 5.7 2e-87 293.3 5.7 1.8 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EGR33616.1 - 8e-05 21.6 0.1 8e-05 21.6 0.1 2.5 2 1 1 3 3 3 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGR33616.1 - 0.00056 18.3 0.0 0.00093 17.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 EGR33616.1 - 0.016 14.1 1.9 0.018 13.9 0.1 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Pkinase PF00069.25 EGR33618.1 - 2.8e-74 249.8 1.7 2.8e-74 249.8 1.7 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33618.1 - 2.8e-43 148.1 0.5 5.3e-43 147.2 0.5 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33618.1 - 1.1e-13 51.2 0.2 2.3e-13 50.1 0.2 1.6 1 0 0 1 1 1 1 Kinase-like EF-hand_6 PF13405.6 EGR33618.1 - 1.7e-06 27.5 6.6 0.0012 18.6 0.1 4.1 5 0 0 5 5 5 2 EF-hand domain Kdo PF06293.14 EGR33618.1 - 1.7e-06 27.5 0.1 3.5e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family EF-hand_7 PF13499.6 EGR33618.1 - 2.3e-05 24.7 4.6 0.1 13.1 0.0 3.6 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_1 PF00036.32 EGR33618.1 - 0.0006 19.2 2.2 0.24 11.0 0.1 3.3 3 0 0 3 3 3 2 EF hand APH PF01636.23 EGR33618.1 - 0.0064 16.4 0.0 0.0096 15.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family CDC4_D PF16856.5 EGR33618.1 - 0.014 15.3 1.5 0.014 15.3 1.5 2.4 2 0 0 2 2 2 0 Cell division control protein 4 dimerisation domain FTA2 PF13095.6 EGR33618.1 - 0.024 14.3 3.0 0.11 12.1 0.1 2.8 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 DUF2999 PF11212.8 EGR33618.1 - 0.18 12.1 7.0 0.95 9.8 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2999) Mito_carr PF00153.27 EGR33619.1 - 1.8e-51 172.0 4.8 7.5e-17 61.0 0.1 3.1 2 1 1 3 3 3 3 Mitochondrial carrier protein TBCC PF07986.12 EGR33620.1 - 1.5e-16 60.2 4.2 1.5e-16 60.2 4.2 2.8 4 1 1 5 5 5 1 Tubulin binding cofactor C CAP_C PF08603.11 EGR33620.1 - 0.022 14.4 11.4 0.053 13.1 10.7 1.8 1 1 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal AWS PF17907.1 EGR33620.1 - 0.56 10.3 6.7 4.5 7.4 1.9 2.8 2 0 0 2 2 2 0 AWS domain DUF3800 PF12686.7 EGR33620.1 - 0.76 10.4 0.0 0.76 10.4 0.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF3800) tRNA-synt_1e PF01406.19 EGR33621.1 - 3.2e-83 279.6 2.8 3.2e-83 279.6 2.8 3.1 3 1 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Pkinase PF00069.25 EGR33621.1 - 8.8e-50 169.5 3.0 8.8e-50 169.5 3.0 3.3 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33621.1 - 1.7e-30 106.2 0.1 4.3e-30 104.9 0.1 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33621.1 - 6.6e-09 35.5 0.9 1.6e-08 34.3 0.9 1.7 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR33621.1 - 0.00099 18.5 0.3 0.003 17.0 0.3 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR33621.1 - 0.023 14.6 0.1 0.037 14.0 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family PIP49_C PF12260.8 EGR33621.1 - 0.13 11.9 0.1 0.13 11.9 0.1 2.8 3 0 0 3 3 3 0 Protein-kinase domain of FAM69 Ephrin_rec_like PF07699.13 EGR33622.1 - 7.2e-50 166.5 162.8 1.5e-06 27.9 9.1 15.1 8 4 6 15 15 15 15 Putative ephrin-receptor like Lipase_3 PF01764.25 EGR33622.1 - 1.6e-21 76.7 0.0 3e-21 75.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) TNFR_c6 PF00020.18 EGR33622.1 - 1.1e-12 48.1 126.0 0.23 11.9 1.4 19.1 10 8 7 17 17 17 16 TNFR/NGFR cysteine-rich region NCD3G PF07562.14 EGR33622.1 - 9.8e-12 44.7 141.5 0.024 14.6 9.5 12.0 9 2 2 11 11 11 11 Nine Cysteines Domain of family 3 GPCR DUF3242 PF11586.8 EGR33622.1 - 0.076 12.8 2.3 0.22 11.3 2.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3242) Pkinase PF00069.25 EGR33623.1 - 2e-50 171.6 0.2 2e-50 171.6 0.2 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33623.1 - 1.9e-15 56.9 0.1 1.1e-14 54.4 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase HxlR PF01638.17 EGR33623.1 - 0.0019 18.0 0.1 0.0045 16.8 0.1 1.7 1 0 0 1 1 1 1 HxlR-like helix-turn-helix FTA2 PF13095.6 EGR33623.1 - 0.036 13.7 0.1 0.036 13.7 0.1 2.2 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Octopine_DH PF02317.17 EGR33623.1 - 0.17 12.0 0.8 0.33 11.0 0.8 1.6 1 1 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Tyrosinase PF00264.20 EGR33623.1 - 0.19 12.0 4.3 0.31 11.3 4.3 1.3 1 0 0 1 1 1 0 Common central domain of tyrosinase Pkinase PF00069.25 EGR33625.1 - 3.6e-67 226.5 0.2 6.8e-67 225.6 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33625.1 - 1.8e-31 109.3 0.0 3.9e-31 108.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33625.1 - 3.7e-05 23.2 1.2 0.00013 21.4 0.1 2.3 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGR33625.1 - 0.039 13.3 0.1 0.08 12.3 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGR33625.1 - 0.058 13.0 0.1 0.058 13.0 0.1 2.4 2 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGR33625.1 - 0.12 11.1 0.1 0.12 11.1 0.1 2.0 2 0 0 2 2 2 0 Fungal protein kinase ALMT PF11744.8 EGR33625.1 - 2.6 6.8 10.9 5.2 5.8 10.9 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter CENP-B_dimeris PF09026.10 EGR33626.1 - 2.2 8.7 8.8 6.5 7.2 8.8 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain COMM_domain PF07258.14 EGR33627.1 - 4.4e-13 49.2 14.6 7.1e-13 48.5 2.9 2.8 3 0 0 3 3 3 2 COMM domain DUF1987 PF09345.10 EGR33627.1 - 0.1 12.3 3.9 0.11 12.2 1.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF1987) EF-hand_7 PF13499.6 EGR33628.1 - 2.4e-19 69.5 0.5 5.8e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR33628.1 - 7.8e-16 56.4 2.1 0.00014 21.1 0.0 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGR33628.1 - 3.7e-15 54.5 0.4 0.00013 21.7 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGR33628.1 - 1.9e-10 39.7 3.6 0.00037 19.9 0.0 3.6 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EGR33628.1 - 1.4e-09 37.7 1.0 0.017 14.9 0.0 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_10 PF14788.6 EGR33628.1 - 2.7e-05 24.0 0.1 0.017 14.9 0.0 3.4 3 1 0 3 3 3 1 EF hand Dockerin_1 PF00404.18 EGR33628.1 - 0.018 15.2 0.0 5.3 7.3 0.0 2.7 2 0 0 2 2 2 0 Dockerin type I domain AvrPphF-ORF-2 PF09143.10 EGR33628.1 - 0.1 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 AvrPphF-ORF-2 SPARC_Ca_bdg PF10591.9 EGR33628.1 - 0.14 12.4 0.1 3.4 8.0 0.0 2.7 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Pkinase PF00069.25 EGR33629.1 - 6.2e-21 74.9 0.3 6.2e-21 74.9 0.3 3.1 3 1 1 4 4 4 2 Protein kinase domain Kelch_4 PF13418.6 EGR33629.1 - 3.7e-13 49.3 0.6 1.4e-06 28.2 0.1 3.5 3 0 0 3 3 3 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EGR33629.1 - 1.3e-12 47.5 0.1 7.9e-08 32.3 0.1 4.1 2 1 2 4 4 4 2 Kelch motif Kelch_1 PF01344.25 EGR33629.1 - 2.7e-12 46.0 0.0 2.6e-06 26.9 0.0 3.5 3 0 0 3 3 3 2 Kelch motif Pkinase_Tyr PF07714.17 EGR33629.1 - 2.2e-11 43.6 0.4 6.9e-11 41.9 0.3 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Kelch_5 PF13854.6 EGR33629.1 - 9.1e-07 28.7 2.3 0.26 11.3 0.3 4.2 4 0 0 4 4 4 2 Kelch motif Kinase-like PF14531.6 EGR33629.1 - 0.0002 20.8 0.1 0.0002 20.8 0.1 2.8 2 1 1 3 3 3 1 Kinase-like Kelch_2 PF07646.15 EGR33629.1 - 0.0013 18.6 0.0 0.86 9.7 0.0 3.2 3 0 0 3 3 3 1 Kelch motif APH PF01636.23 EGR33629.1 - 0.0066 16.4 0.0 0.01 15.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kelch_3 PF13415.6 EGR33629.1 - 0.038 14.3 0.0 0.26 11.6 0.0 2.5 2 0 0 2 2 2 0 Galactose oxidase, central domain FAA_hydrolase_N PF09298.11 EGR33631.1 - 0.65 10.2 4.4 0.54 10.5 2.5 1.8 1 1 0 1 1 1 0 Fumarylacetoacetase N-terminal DYW_deaminase PF14432.6 EGR33631.1 - 3 7.7 7.9 0.32 10.9 0.5 2.2 1 1 1 2 2 2 0 DYW family of nucleic acid deaminases Cullin PF00888.22 EGR33634.1 - 4.4e-106 355.9 56.7 4.4e-106 355.9 56.7 1.8 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 EGR33634.1 - 3.8e-23 81.3 3.7 3.8e-23 81.3 3.7 3.2 3 1 1 4 4 4 1 Cullin protein neddylation domain MLD PF11647.8 EGR33634.1 - 0.34 11.2 3.4 0.89 9.9 0.6 3.3 2 0 0 2 2 2 0 Membrane Localization Domain Amidase PF01425.21 EGR33635.1 - 2.7e-95 320.0 0.0 3.1e-95 319.8 0.0 1.0 1 0 0 1 1 1 1 Amidase ADH_zinc_N PF00107.26 EGR33637.1 - 1e-24 87.0 0.1 2e-24 86.0 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N_2 PF16884.5 EGR33637.1 - 1e-17 63.9 0.0 1.8e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N_2 PF13602.6 EGR33637.1 - 4.7e-11 43.9 0.0 8.5e-11 43.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF2855 PF11017.8 EGR33637.1 - 0.0056 16.5 0.0 0.0088 15.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2855) TrkA_N PF02254.18 EGR33637.1 - 0.015 15.5 0.0 0.028 14.7 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain LRR_6 PF13516.6 EGR33638.1 - 1.1e-10 40.7 0.1 2.4 8.4 0.1 7.0 7 0 0 7 7 7 4 Leucine Rich repeat Dynein_light PF01221.18 EGR33639.1 - 5.5e-27 93.9 2.7 7.1e-27 93.6 2.6 1.3 1 1 0 1 1 1 1 Dynein light chain type 1 Chromo PF00385.24 EGR33640.1 - 3.9e-13 49.1 9.6 2.6e-11 43.3 4.3 2.3 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 EGR33640.1 - 3.1e-05 24.0 3.3 0.034 14.2 0.1 2.5 2 0 0 2 2 2 2 Chromo shadow domain Ribosomal_L12 PF00542.19 EGR33641.1 - 8.1e-23 80.6 3.4 8.1e-23 80.6 3.4 2.1 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain PIG-P PF08510.12 EGR33641.1 - 0.0015 18.4 1.3 0.0055 16.6 1.3 2.2 1 1 0 1 1 1 1 PIG-P Pal1 PF08316.11 EGR33641.1 - 0.41 11.4 4.3 0.73 10.6 0.4 2.3 2 0 0 2 2 2 0 Pal1 cell morphology protein Pkinase PF00069.25 EGR33642.1 - 8e-71 238.5 7.2 9.1e-71 238.3 7.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33642.1 - 1.6e-45 155.4 2.0 2e-45 155.1 2.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR33642.1 - 3.2e-06 26.2 0.1 6e-06 25.3 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGR33642.1 - 7.8e-06 25.4 0.5 3.7e-05 23.2 0.3 2.2 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EGR33642.1 - 2.9e-05 23.5 0.1 5.5e-05 22.6 0.1 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Glyco_hydro_35 PF01301.19 EGR33643.1 - 6.5e-85 285.5 5.4 6.5e-85 285.5 5.4 1.4 1 1 0 1 1 1 1 Glycosyl hydrolases family 35 BetaGal_dom4_5 PF13364.6 EGR33643.1 - 3e-05 24.5 1.4 0.0001 22.8 0.7 2.3 2 0 0 2 2 2 1 Beta-galactosidase jelly roll domain HATPase_c PF02518.26 EGR33644.1 - 3.5e-12 46.8 0.2 5.2e-12 46.3 0.2 1.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase YrzK PF17449.2 EGR33646.1 - 1.4e-06 28.5 0.6 13 6.1 0.0 5.7 6 0 0 6 6 6 1 Uncharacterized YrzK-like DBD_HTH PF18430.1 EGR33646.1 - 0.026 14.3 0.3 1.7e+02 2.1 0.0 4.9 5 0 0 5 5 5 0 Putative DNA-binding domain V4R PF02830.18 EGR33646.1 - 0.081 13.0 38.1 1.5 8.9 0.6 6.7 7 0 0 7 7 7 0 V4R domain APC_r PF05923.12 EGR33646.1 - 0.26 11.1 2.6 1.5e+02 2.2 0.0 5.6 7 0 0 7 7 7 0 APC repeat Fe_hyd_lg_C PF02906.14 EGR33647.1 - 3.3e-42 144.8 3.0 9e-40 136.9 0.3 3.1 2 1 1 3 3 3 2 Iron only hydrogenase large subunit, C-terminal domain MHC2-interact PF09307.10 EGR33647.1 - 0.012 15.6 0.3 0.031 14.3 0.3 1.7 1 0 0 1 1 1 0 CLIP, MHC2 interacting HTH_47 PF16221.5 EGR33647.1 - 0.14 11.8 0.0 0.33 10.5 0.0 1.6 1 0 0 1 1 1 0 winged helix-turn-helix DNA_pol_B PF00136.21 EGR33649.1 - 1.1e-84 284.7 13.1 1.1e-84 284.7 13.1 3.7 3 2 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EGR33649.1 - 4.1e-11 42.6 26.0 1.1e-07 31.3 9.5 6.3 4 1 2 6 6 6 3 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EGR33649.1 - 1.2e-05 25.6 16.1 1.2e-05 25.6 16.1 3.6 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta RecR PF02132.15 EGR33649.1 - 0.19 11.3 11.6 0.014 14.9 5.1 2.5 2 0 0 2 2 2 0 RecR protein Tubulin PF00091.25 EGR33650.1 - 9.8e-69 231.5 0.0 1.8e-68 230.6 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGR33650.1 - 7.1e-42 142.5 0.1 1.1e-41 142.0 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGR33650.1 - 0.00023 21.5 0.0 0.00058 20.2 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EGR33650.1 - 0.0071 16.1 0.0 0.014 15.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EGR33650.1 - 0.0087 15.3 0.1 0.022 14.0 0.0 1.6 2 0 0 2 2 2 1 Tubulin like UMPH-1 PF05822.12 EGR33651.1 - 5.1e-23 81.9 2.5 6e-23 81.6 2.5 1.1 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 EGR33651.1 - 0.013 16.0 0.0 0.045 14.1 0.0 1.9 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Raco_middle PF17651.1 EGR33651.1 - 0.11 12.2 0.2 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 RACo middle region RabGAP-TBC PF00566.18 EGR33652.1 - 0.022 14.4 0.4 0.03 14.0 0.1 1.4 1 1 0 1 1 1 0 Rab-GTPase-TBC domain zf-C3HC4_3 PF13920.6 EGR33653.1 - 1.1e-14 54.0 15.8 1.6e-14 53.5 15.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGR33653.1 - 2.2e-07 30.6 13.9 3e-07 30.2 13.9 1.2 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGR33653.1 - 2.9e-06 27.5 16.7 4.1e-06 27.0 16.7 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGR33653.1 - 0.0016 18.3 15.9 0.0029 17.5 15.9 1.4 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGR33653.1 - 0.021 14.7 17.4 0.029 14.2 17.4 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGR33653.1 - 1.9 8.6 13.3 0.63 10.1 9.8 1.9 1 1 1 2 2 2 0 RING-type zinc-finger Pkinase PF00069.25 EGR33654.1 - 1.9e-26 93.0 0.0 2.1e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33654.1 - 6.3e-13 48.6 0.0 7.1e-13 48.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Helicase_Sgs1 PF11408.8 EGR33654.1 - 0.033 14.2 0.4 0.045 13.8 0.4 1.2 1 0 0 1 1 1 0 Sgs1 RecQ helicase Anoctamin PF04547.12 EGR33655.1 - 7.3e-97 325.0 24.2 7.3e-97 325.0 24.2 1.8 2 1 0 2 2 2 1 Calcium-activated chloride channel DUF4945 PF16303.5 EGR33655.1 - 0.032 14.2 0.7 0.45 10.5 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4945) ZnuA PF01297.17 EGR33655.1 - 0.14 11.5 2.0 0.27 10.6 2.0 1.4 1 0 0 1 1 1 0 Zinc-uptake complex component A periplasmic Hydrolase_4 PF12146.8 EGR33657.1 - 0.052 12.8 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Pkinase PF00069.25 EGR33658.1 - 4.7e-67 226.1 1.4 4.7e-67 226.1 1.4 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33658.1 - 2.7e-37 128.5 0.1 4.1e-37 127.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33658.1 - 0.00012 21.5 0.0 0.00028 20.3 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR33658.1 - 0.017 14.5 0.6 0.027 13.8 0.1 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Imm7 PF15585.6 EGR33658.1 - 0.032 14.5 0.7 0.058 13.7 0.7 1.4 1 0 0 1 1 1 0 Immunity protein 7 WD40 PF00400.32 EGR33659.1 - 3.4e-29 100.5 6.8 1.8e-06 28.5 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR33659.1 - 1.7e-16 60.3 5.9 1.8e-07 31.4 0.3 4.6 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGR33659.1 - 2.8e-09 37.1 1.6 2.9e-06 27.3 0.1 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGR33659.1 - 0.00018 20.9 0.0 0.14 11.5 0.0 3.0 2 1 1 3 3 3 2 WD40-like domain Nup160 PF11715.8 EGR33659.1 - 0.0004 19.2 0.3 0.0062 15.2 0.0 2.7 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGR33659.1 - 0.0061 15.6 0.3 0.18 10.8 0.0 2.5 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein HPS3_N PF14761.6 EGR33659.1 - 0.012 15.2 0.3 0.88 9.1 0.0 2.9 3 0 0 3 3 3 0 Hermansky-Pudlak syndrome 3 Invas_SpaK PF03519.14 EGR33659.1 - 0.022 14.8 0.2 10 6.3 0.0 3.3 3 0 0 3 3 3 0 Invasion protein B family IATP PF04568.12 EGR33660.1 - 0.14 12.6 0.4 0.14 12.6 0.4 1.9 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP Pre-PUA PF17832.1 EGR33661.1 - 9.2e-20 71.1 1.5 1.6e-19 70.4 1.5 1.4 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EGR33661.1 - 6.3e-08 32.5 0.2 9.2e-08 31.9 0.2 1.3 1 0 0 1 1 1 1 PUA domain Peptidase_M8 PF01457.16 EGR33662.1 - 8.4e-26 90.7 0.1 1e-25 90.5 0.1 1.0 1 0 0 1 1 1 1 Leishmanolysin Pkinase PF00069.25 EGR33665.1 - 8.7e-70 235.1 0.4 8.7e-70 235.1 0.4 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33665.1 - 1.1e-36 126.4 0.1 2.2e-36 125.4 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33665.1 - 4.1e-08 32.9 0.8 7.3e-08 32.1 0.2 2.0 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGR33665.1 - 8.2e-08 31.6 5.9 8.2e-08 31.6 5.9 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EGR33665.1 - 0.022 14.1 1.8 0.029 13.7 0.1 2.1 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR33665.1 - 0.036 12.8 5.3 0.012 14.5 1.7 2.0 2 1 0 2 2 2 0 Fungal protein kinase EutB PF06751.11 EGR33665.1 - 0.043 12.6 1.6 0.076 11.8 1.6 1.3 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) APH PF01636.23 EGR33665.1 - 0.051 13.5 0.1 0.72 9.7 0.1 2.0 1 1 0 2 2 2 0 Phosphotransferase enzyme family CEP170_C PF15308.6 EGR33665.1 - 0.75 8.3 3.9 1 7.8 3.9 1.1 1 0 0 1 1 1 0 CEP170 C-terminus TTL PF03133.15 EGR33666.1 - 1.6e-36 126.0 7.1 8.1e-25 87.5 2.0 2.1 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR33666.1 - 6.7e-06 25.5 0.2 0.00082 18.7 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR33666.1 - 0.0051 16.1 0.0 0.01 15.1 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp WD40 PF00400.32 EGR33667.1 - 1.2e-14 54.5 9.0 3.3e-05 24.6 0.1 5.1 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR33667.1 - 6.3e-13 48.8 0.8 2.1e-05 24.7 0.2 3.0 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 EGR33667.1 - 0.0014 18.1 0.0 0.023 14.0 0.0 2.2 1 1 1 2 2 2 1 Neuroblastoma-amplified sequence, N terminal DUF3244 PF11589.8 EGR33668.1 - 0.079 13.1 3.0 0.16 12.1 0.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3244) Furin-like_2 PF15913.5 EGR33669.1 - 0.0014 18.7 25.7 0.026 14.7 11.2 2.4 1 1 1 2 2 2 2 Furin-like repeat, cysteine-rich VSP PF03302.13 EGR33669.1 - 0.047 12.5 34.3 0.33 9.8 13.2 2.1 1 1 1 2 2 2 0 Giardia variant-specific surface protein Ephrin_rec_like PF07699.13 EGR33669.1 - 0.24 11.2 36.2 0.27 11.0 11.6 4.5 2 2 1 3 3 3 0 Putative ephrin-receptor like AAA_22 PF13401.6 EGR33672.1 - 0.027 14.8 0.2 5.4 7.3 0.0 3.2 2 1 0 2 2 2 0 AAA domain SHNi-TPR PF10516.9 EGR33673.1 - 0.024 14.1 0.5 0.024 14.1 0.5 2.2 2 0 0 2 2 2 0 SHNi-TPR DUF3417 PF11897.8 EGR33673.1 - 0.032 14.7 0.9 0.032 14.7 0.9 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3417) TPR_18 PF13512.6 EGR33673.1 - 0.091 12.9 0.1 0.091 12.9 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Kelch_1 PF01344.25 EGR33674.1 - 1.1e-33 114.5 0.8 1.5e-10 40.5 0.0 3.3 3 0 0 3 3 3 3 Kelch motif Kelch_6 PF13964.6 EGR33674.1 - 2.7e-21 75.1 0.6 1.1e-06 28.7 0.0 3.1 2 1 1 3 3 3 3 Kelch motif Kelch_4 PF13418.6 EGR33674.1 - 4.1e-15 55.5 0.1 7.9e-06 25.8 0.0 3.1 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_3 PF13415.6 EGR33674.1 - 3.6e-12 46.3 0.0 0.0016 18.6 0.0 3.2 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_2 PF07646.15 EGR33674.1 - 2.4e-09 36.8 0.9 0.00048 20.0 0.0 3.4 3 1 0 3 3 3 3 Kelch motif Kelch_5 PF13854.6 EGR33674.1 - 1.3e-05 25.0 5.1 1.1 9.4 0.1 4.2 4 0 0 4 4 4 3 Kelch motif Ion_trans PF00520.31 EGR33675.1 - 6.4e-38 130.4 34.4 9.4e-24 84.0 14.5 2.8 3 0 0 3 3 3 2 Ion transport protein Sod_Fe_C PF02777.18 EGR33675.1 - 0.059 13.5 0.1 0.059 13.5 0.1 2.8 3 1 0 3 3 3 0 Iron/manganese superoxide dismutases, C-terminal domain KOW PF00467.29 EGR33676.1 - 1.2e-15 56.8 10.8 0.00047 20.0 0.5 4.6 4 0 0 4 4 4 4 KOW motif Spt5-NGN PF03439.13 EGR33676.1 - 2.9e-12 46.3 0.0 6.9e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section DUF3912 PF13051.6 EGR33676.1 - 0.078 13.3 0.1 0.078 13.3 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3912) MORN PF02493.20 EGR33677.1 - 2.2e-20 71.2 29.1 3.3e-06 26.7 1.9 5.5 5 0 0 5 5 5 5 MORN repeat Man-6-P_recep PF02157.15 EGR33677.1 - 0.001 18.2 4.2 0.001 18.2 4.2 1.8 2 0 0 2 2 2 1 Mannose-6-phosphate receptor DUF2116 PF09889.9 EGR33677.1 - 0.52 10.3 2.3 1.7 8.7 2.3 1.9 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) PDEase_I PF00233.19 EGR33678.1 - 6.4e-78 261.8 10.0 6.4e-78 261.8 10.0 2.7 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase Ion_trans PF00520.31 EGR33678.1 - 2.5e-11 43.3 12.2 2.5e-11 43.3 12.2 2.1 3 0 0 3 3 3 1 Ion transport protein HECT PF00632.25 EGR33680.1 - 8.5e-81 271.8 1.4 1.1e-80 271.4 1.4 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) BH4 PF02180.17 EGR33680.1 - 0.044 13.6 0.2 0.093 12.6 0.2 1.5 1 0 0 1 1 1 0 Bcl-2 homology region 4 Lipin_mid PF16876.5 EGR33685.1 - 0.58 10.3 7.6 7 6.9 7.3 2.4 1 1 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain DUF4050 PF13259.6 EGR33685.1 - 6 7.1 8.6 13 6.0 8.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF4050) NIF PF03031.18 EGR33687.1 - 6.6e-50 168.9 1.3 1e-49 168.3 1.3 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase HAD_2 PF13419.6 EGR33687.1 - 0.0026 17.9 2.6 0.084 13.0 0.1 2.3 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Acid_PPase PF12689.7 EGR33687.1 - 0.023 14.5 0.0 0.04 13.8 0.0 1.4 1 0 0 1 1 1 0 Acid Phosphatase Hydrolase PF00702.26 EGR33687.1 - 0.17 12.1 0.0 1.5 9.0 0.1 1.9 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase PNK3P PF08645.11 EGR33687.1 - 0.65 9.7 3.9 0.45 10.2 0.1 2.2 2 0 0 2 2 2 0 Polynucleotide kinase 3 phosphatase ESP PF16590.5 EGR33687.1 - 4 7.8 7.6 0.46 10.8 2.6 2.0 2 1 1 3 3 3 0 Exocrine gland-secreting peptide MFS_1 PF07690.16 EGR33688.1 - 2.2e-18 66.3 29.4 2.2e-18 66.3 29.4 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_3 PF05977.13 EGR33688.1 - 0.0016 16.9 0.6 0.0016 16.9 0.6 1.9 2 0 0 2 2 2 1 Transmembrane secretion effector CrgA PF06781.12 EGR33688.1 - 0.053 13.6 1.8 0.46 10.6 1.8 2.7 1 0 0 1 1 1 0 Cell division protein CrgA SDA1 PF05285.12 EGR33689.1 - 0.001 18.6 21.3 0.0012 18.4 21.3 1.1 1 0 0 1 1 1 1 SDA1 BtpA PF03437.15 EGR33689.1 - 0.0013 18.2 1.2 0.084 12.3 0.0 2.1 2 0 0 2 2 2 2 BtpA family Endostatin PF06482.11 EGR33689.1 - 0.012 15.1 4.3 0.017 14.6 4.3 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Sin_N PF04801.13 EGR33689.1 - 0.031 13.5 16.6 0.038 13.2 16.6 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Presenilin PF01080.17 EGR33689.1 - 0.054 12.3 17.0 0.064 12.0 17.0 1.1 1 0 0 1 1 1 0 Presenilin Nop14 PF04147.12 EGR33689.1 - 0.5 8.5 30.8 0.65 8.1 30.8 1.1 1 0 0 1 1 1 0 Nop14-like family V_ATPase_I PF01496.19 EGR33689.1 - 0.53 8.1 15.5 0.59 8.0 15.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Spore_coat_CotO PF14153.6 EGR33689.1 - 0.59 10.0 24.6 0.95 9.4 24.6 1.2 1 0 0 1 1 1 0 Spore coat protein CotO ALMT PF11744.8 EGR33689.1 - 3.3 6.5 13.8 4.4 6.0 13.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter BUD22 PF09073.10 EGR33689.1 - 4.5 6.5 32.8 5.9 6.1 32.8 1.1 1 0 0 1 1 1 0 BUD22 TMEM51 PF15345.6 EGR33689.1 - 9.9 5.9 12.1 16 5.3 12.1 1.3 1 0 0 1 1 1 0 Transmembrane protein 51 Ion_trans_2 PF07885.16 EGR33692.1 - 8.6e-12 44.9 7.2 1.6e-11 44.0 7.1 1.6 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGR33692.1 - 3.6e-06 26.4 6.2 7.4e-06 25.4 6.2 1.5 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 EGR33692.1 - 0.004 17.2 0.1 0.007 16.4 0.1 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Methyltr_RsmF_N PF17125.5 EGR33692.1 - 0.018 15.5 0.8 0.04 14.4 0.8 1.6 1 0 0 1 1 1 0 N-terminal domain of 16S rRNA methyltransferase RsmF Peptidase_M8 PF01457.16 EGR33695.1 - 3.7e-37 128.2 1.3 1.7e-36 126.0 0.4 1.7 1 1 1 2 2 2 1 Leishmanolysin EGF_alliinase PF04863.13 EGR33695.1 - 0.041 14.3 0.3 0.041 14.3 0.3 2.2 2 0 0 2 2 2 0 Alliinase EGF-like domain BSP PF04450.12 EGR33695.1 - 0.12 12.1 0.0 0.25 11.1 0.0 1.5 1 0 0 1 1 1 0 Peptidase of plants and bacteria Aspzincin_M35 PF14521.6 EGR33695.1 - 0.13 12.9 2.6 0.79 10.3 0.0 2.5 2 0 0 2 2 2 0 Lysine-specific metallo-endopeptidase Peptidase_M8 PF01457.16 EGR33696.1 - 1.2e-06 27.5 0.2 1.3e-06 27.4 0.2 1.0 1 0 0 1 1 1 1 Leishmanolysin Homoserine_dh PF00742.19 EGR33696.1 - 0.13 12.2 0.0 0.16 11.9 0.0 1.0 1 0 0 1 1 1 0 Homoserine dehydrogenase Ras PF00071.22 EGR33697.1 - 2.5e-59 199.5 2.4 3e-59 199.3 2.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR33697.1 - 8.2e-32 110.0 1.5 1.3e-31 109.3 1.5 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR33697.1 - 1e-14 54.4 1.1 1.2e-14 54.2 1.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGR33697.1 - 3.7e-05 23.2 0.3 4.1e-05 23.1 0.3 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.17 EGR33697.1 - 4.1e-05 23.5 0.8 0.00011 22.0 0.0 1.8 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EGR33697.1 - 0.00013 22.0 0.1 0.051 13.5 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EGR33697.1 - 0.0012 18.2 1.2 0.0027 17.1 1.2 1.7 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGR33697.1 - 0.002 17.7 2.1 0.0031 17.1 0.5 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGR33697.1 - 0.0046 17.0 0.3 0.0078 16.3 0.3 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Kinesin PF00225.23 EGR33698.1 - 1.4e-21 76.8 0.1 1.5e-21 76.7 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain PFK PF00365.20 EGR33700.1 - 3.9e-19 69.1 0.0 3.6e-18 65.9 0.0 2.0 2 0 0 2 2 2 1 Phosphofructokinase His_binding PF02098.16 EGR33700.1 - 0.023 14.8 0.2 0.047 13.7 0.2 1.5 1 0 0 1 1 1 0 Tick histamine binding protein PFK PF00365.20 EGR33701.1 - 1.8e-43 148.9 1.9 2.8e-43 148.3 1.9 1.2 1 0 0 1 1 1 1 Phosphofructokinase MFS_1 PF07690.16 EGR33707.1 - 2.8e-11 42.9 16.1 3.9e-11 42.5 16.1 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGR33707.1 - 3e-06 26.4 15.1 2.5e-05 23.3 2.5 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter cwf21 PF08312.12 EGR33709.1 - 7.8e-08 32.3 15.2 7.8e-08 32.3 15.2 2.2 2 0 0 2 2 2 1 cwf21 domain AAA_26 PF13500.6 EGR33709.1 - 8.9 6.1 7.5 1.3 8.8 3.5 1.7 2 0 0 2 2 2 0 AAA domain DUF2475 PF10629.9 EGR33710.1 - 9.7e-11 41.7 2.8 2.2e-06 27.8 0.8 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF2475) SPATA48 PF15073.6 EGR33710.1 - 0.0024 18.1 0.6 0.33 11.2 0.1 2.2 1 1 1 2 2 2 2 Spermatogenesis-associated protein 48 LRR_6 PF13516.6 EGR33712.1 - 0.0047 16.9 18.8 0.015 15.3 0.1 6.2 5 2 2 7 7 7 2 Leucine Rich repeat DUF1514 PF07438.11 EGR33712.1 - 0.038 13.9 1.8 0.34 10.8 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1514) MORN PF02493.20 EGR33713.1 - 1.7e-30 103.1 49.7 1.9e-07 30.5 2.5 7.4 7 0 0 7 7 7 7 MORN repeat DUF1117 PF06547.12 EGR33713.1 - 0.013 16.1 0.6 0.077 13.5 0.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1117) Evr1_Alr PF04777.13 EGR33714.1 - 1.3e-27 96.1 3.6 2e-27 95.6 2.9 1.6 2 0 0 2 2 2 1 Erv1 / Alr family zf-CSL PF05207.13 EGR33714.1 - 0.0087 15.8 0.9 2.5 7.9 0.1 2.5 2 0 0 2 2 2 2 CSL zinc finger Pkinase PF00069.25 EGR33715.1 - 6.9e-43 146.9 0.0 7.9e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33715.1 - 2.7e-16 59.6 0.0 3.4e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR33715.1 - 0.0016 17.4 0.0 0.0026 16.8 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGR33715.1 - 0.0036 17.3 0.1 0.0052 16.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR33715.1 - 0.0063 15.9 0.0 0.008 15.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EGR33715.1 - 0.025 13.6 0.1 0.041 12.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Zip PF02535.22 EGR33716.1 - 5.8e-35 121.1 4.1 7.2e-35 120.8 4.1 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Connexin PF00029.19 EGR33716.1 - 0.084 12.6 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 Connexin ETRAMP PF09716.10 EGR33716.1 - 0.79 9.8 6.7 0.21 11.7 2.2 2.5 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Gaa1 PF04114.14 EGR33717.1 - 0.003 16.7 0.3 0.0035 16.4 0.3 1.0 1 0 0 1 1 1 1 Gaa1-like, GPI transamidase component Polyoma_coat2 PF00761.20 EGR33717.1 - 0.034 13.9 0.5 0.04 13.6 0.5 1.0 1 0 0 1 1 1 0 Polyomavirus coat protein Sec20 PF03908.13 EGR33717.1 - 0.083 12.8 5.9 0.074 13.0 1.3 2.0 1 1 1 2 2 2 0 Sec20 DUF3713 PF12506.8 EGR33717.1 - 0.11 12.7 8.9 0.062 13.6 6.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) YtxH PF12732.7 EGR33717.1 - 0.92 10.1 6.0 0.43 11.1 1.6 2.2 1 1 1 2 2 2 0 YtxH-like protein AFP_2 PF18815.1 EGR33717.1 - 9.8 6.5 9.2 9.5 6.6 4.1 2.6 1 1 1 2 2 2 0 Bacterial antifreeze protein repeat T2SSC PF11356.8 EGR33720.1 - 1 9.3 5.9 1.4 8.8 0.7 2.8 2 1 1 3 3 3 0 Type II secretion system protein C SET PF00856.28 EGR33721.1 - 1.1e-11 45.4 2.5 3.9e-11 43.6 0.4 2.5 2 1 0 2 2 2 1 SET domain ET PF01684.16 EGR33721.1 - 0.053 13.9 1.8 0.14 12.5 1.8 1.7 1 0 0 1 1 1 0 ET module DEAD PF00270.29 EGR33722.1 - 1.3e-36 126.0 0.5 4e-34 117.9 0.0 3.3 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR33722.1 - 2.5e-28 98.7 0.2 2.5e-28 98.7 0.2 4.3 6 1 0 6 6 6 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGR33722.1 - 0.033 14.5 0.5 0.25 11.6 0.5 2.5 1 1 0 1 1 1 0 AAA domain Proteasome PF00227.26 EGR33723.1 - 3e-26 92.1 2.4 2.4e-24 85.9 2.4 2.0 1 1 0 1 1 1 1 Proteasome subunit Inhibitor_I69 PF13734.6 EGR33723.1 - 0.0054 17.1 0.1 0.019 15.4 0.0 2.0 2 0 0 2 2 2 1 Spi protease inhibitor dNK PF01712.19 EGR33723.1 - 0.022 14.6 1.7 0.029 14.2 1.7 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase Clat_adaptor_s PF01217.20 EGR33725.1 - 5.5e-50 169.0 8.3 6e-50 168.9 8.3 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Tropomyosin_1 PF12718.7 EGR33726.1 - 2.5e-12 47.2 87.6 2.5e-05 24.5 22.4 7.8 1 1 6 7 7 7 4 Tropomyosin like Spc7 PF08317.11 EGR33726.1 - 2.7e-10 39.6 94.6 0.00026 20.0 22.8 4.6 1 1 3 4 4 4 4 Spc7 kinetochore protein AAA_13 PF13166.6 EGR33726.1 - 5.8e-10 38.5 73.4 5.4e-06 25.4 25.4 3.8 1 1 2 3 3 3 3 AAA domain ATG16 PF08614.11 EGR33726.1 - 8.7e-10 39.2 90.8 0.00086 19.6 13.3 7.5 1 1 5 6 6 6 3 Autophagy protein 16 (ATG16) Filament PF00038.21 EGR33726.1 - 1.6e-08 34.6 88.4 0.0048 16.5 22.5 5.5 1 1 4 5 5 5 4 Intermediate filament protein GAS PF13851.6 EGR33726.1 - 2.2e-08 33.7 99.1 0.0061 15.9 20.7 5.2 2 1 3 5 5 5 3 Growth-arrest specific micro-tubule binding Tropomyosin PF00261.20 EGR33726.1 - 1.6e-07 30.9 84.8 1.4e-06 27.9 38.0 4.5 1 1 3 4 4 4 3 Tropomyosin TMF_DNA_bd PF12329.8 EGR33726.1 - 1.7e-07 31.1 103.5 2.1e-05 24.4 6.9 9.8 4 3 6 10 10 9 2 TATA element modulatory factor 1 DNA binding MscS_porin PF12795.7 EGR33726.1 - 2.7e-07 30.4 87.6 0.025 14.1 20.3 4.6 2 1 0 3 3 3 3 Mechanosensitive ion channel porin domain ADIP PF11559.8 EGR33726.1 - 9.3e-07 29.0 98.0 0.12 12.5 20.3 8.1 1 1 7 8 8 8 4 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 EGR33726.1 - 5.8e-06 26.0 95.9 0.02 14.4 14.7 4.4 1 1 3 4 4 4 3 Golgin subfamily A member 5 TMF_TATA_bd PF12325.8 EGR33726.1 - 7e-06 26.2 95.1 0.0019 18.4 10.8 6.6 1 1 4 6 6 6 3 TATA element modulatory factor 1 TATA binding BLOC1_2 PF10046.9 EGR33726.1 - 1.4e-05 25.3 83.4 0.029 14.7 5.2 8.0 1 1 5 7 7 7 3 Biogenesis of lysosome-related organelles complex-1 subunit 2 TPR_MLP1_2 PF07926.12 EGR33726.1 - 2e-05 24.6 88.9 0.032 14.3 19.5 6.3 2 1 5 7 7 7 5 TPR/MLP1/MLP2-like protein DUF5082 PF16888.5 EGR33726.1 - 2.6e-05 24.5 94.1 0.0005 20.3 13.4 8.9 2 2 8 10 10 10 3 Domain of unknown function (DUF5082) Fez1 PF06818.15 EGR33726.1 - 2.8e-05 24.7 79.6 0.96 9.9 16.9 5.3 1 1 3 4 4 4 2 Fez1 SlyX PF04102.12 EGR33726.1 - 2.8e-05 24.6 90.9 0.034 14.8 0.1 10.1 2 2 8 10 10 9 3 SlyX DHR10 PF18595.1 EGR33726.1 - 6e-05 23.1 97.1 0.0099 15.9 20.4 5.7 2 1 3 5 5 5 4 Designed helical repeat protein 10 domain DUF4200 PF13863.6 EGR33726.1 - 0.0001 22.7 111.4 0.17 12.3 20.6 8.0 1 1 7 8 8 7 4 Domain of unknown function (DUF4200) DUF1192 PF06698.11 EGR33726.1 - 0.00012 22.0 38.7 0.0085 16.1 1.6 9.2 7 4 3 10 10 9 3 Protein of unknown function (DUF1192) FlaC_arch PF05377.11 EGR33726.1 - 0.0002 21.7 63.2 0.013 15.8 0.5 10.3 7 2 3 10 10 10 3 Flagella accessory protein C (FlaC) Lebercilin PF15619.6 EGR33726.1 - 0.00024 20.9 96.4 0.035 13.8 29.2 6.1 1 1 5 6 6 6 3 Ciliary protein causing Leber congenital amaurosis disease THOC7 PF05615.13 EGR33726.1 - 0.00041 20.6 84.6 0.01 16.1 20.9 7.2 1 1 6 7 7 7 1 Tho complex subunit 7 DUF724 PF05266.14 EGR33726.1 - 0.00075 19.4 80.1 0.0078 16.1 14.3 6.4 1 1 5 6 6 6 2 Protein of unknown function (DUF724) MAD PF05557.13 EGR33726.1 - 0.00075 18.0 104.4 0.17 10.2 23.5 4.4 1 1 1 3 3 3 2 Mitotic checkpoint protein DUF4201 PF13870.6 EGR33726.1 - 0.0018 18.0 98.1 0.19 11.5 8.6 6.9 1 1 3 5 5 5 2 Domain of unknown function (DUF4201) CALCOCO1 PF07888.11 EGR33726.1 - 0.002 17.1 84.6 0.0065 15.4 36.5 3.2 1 1 2 3 3 3 2 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4407 PF14362.6 EGR33726.1 - 0.0024 17.3 61.5 0.33 10.3 17.9 4.8 1 1 3 4 4 4 2 Domain of unknown function (DUF4407) PUB PF09409.10 EGR33726.1 - 0.0027 17.6 2.1 0.087 12.8 0.1 2.9 2 0 0 2 2 2 1 PUB domain Alpha-2-MRAP_C PF06401.11 EGR33726.1 - 0.0031 17.5 18.5 0.0031 17.5 18.5 5.3 1 1 3 4 4 2 1 Alpha-2-macroglobulin RAP, C-terminal domain Chitin_synth_1N PF08407.11 EGR33726.1 - 0.0051 16.7 0.2 0.022 14.7 0.2 2.2 1 0 0 1 1 1 1 Chitin synthase N-terminal DUF3584 PF12128.8 EGR33726.1 - 0.0053 14.3 82.8 0.11 10.0 41.1 3.0 1 1 1 3 3 3 3 Protein of unknown function (DUF3584) UPF0242 PF06785.11 EGR33726.1 - 0.0062 16.7 12.3 0.0062 16.7 12.3 6.0 1 1 5 6 6 6 2 Uncharacterised protein family (UPF0242) N-terminus DUF4094 PF13334.6 EGR33726.1 - 0.0078 16.6 4.0 0.0078 16.6 4.0 7.7 3 3 5 8 8 7 1 Domain of unknown function (DUF4094) CENP-F_leu_zip PF10473.9 EGR33726.1 - 0.0079 16.2 95.4 0.35 10.9 20.7 5.5 1 1 1 4 4 4 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GP20 PF06810.11 EGR33726.1 - 0.0084 15.9 1.8 0.0084 15.9 1.8 8.1 2 1 4 7 7 7 1 Phage minor structural protein GP20 PspA_IM30 PF04012.12 EGR33726.1 - 0.0087 15.7 82.2 0.0097 15.5 9.5 7.6 1 1 7 8 8 8 2 PspA/IM30 family FPP PF05911.11 EGR33726.1 - 0.0089 14.3 92.7 0.27 9.4 24.5 4.5 1 1 3 4 4 4 3 Filament-like plant protein, long coiled-coil FAM76 PF16046.5 EGR33726.1 - 0.0094 15.3 85.8 0.024 14.0 13.0 6.7 1 1 5 6 6 6 2 FAM76 protein Laminin_II PF06009.12 EGR33726.1 - 0.0099 15.9 7.9 0.0099 15.9 7.9 5.9 2 2 5 7 7 7 1 Laminin Domain II Wtap PF17098.5 EGR33726.1 - 0.015 15.2 7.7 0.015 15.2 7.7 5.1 1 1 3 4 4 2 0 WTAP/Mum2p family DUF641 PF04859.12 EGR33726.1 - 0.015 15.6 76.2 0.037 14.4 7.1 7.9 2 2 5 7 7 6 0 Plant protein of unknown function (DUF641) BRE1 PF08647.11 EGR33726.1 - 0.018 15.1 6.6 0.018 15.1 6.6 8.2 2 2 5 7 7 6 0 BRE1 E3 ubiquitin ligase Med9 PF07544.13 EGR33726.1 - 0.019 15.0 4.9 0.019 15.0 4.9 8.5 3 3 4 7 7 7 0 RNA polymerase II transcription mediator complex subunit 9 COG5 PF10392.9 EGR33726.1 - 0.022 14.9 48.2 0.17 12.0 8.1 6.9 2 2 4 6 6 6 0 Golgi transport complex subunit 5 DUF1664 PF07889.12 EGR33726.1 - 0.022 14.8 68.6 0.88 9.6 1.5 7.3 1 1 5 7 7 7 0 Protein of unknown function (DUF1664) DUF4164 PF13747.6 EGR33726.1 - 0.028 14.7 51.7 0.067 13.5 2.0 6.8 3 3 4 7 7 7 0 Domain of unknown function (DUF4164) EzrA PF06160.12 EGR33726.1 - 0.049 11.8 86.3 0.99 7.5 64.3 3.8 1 1 1 2 2 2 0 Septation ring formation regulator, EzrA HOOK PF05622.12 EGR33726.1 - 0.067 11.3 94.7 0.17 10.0 50.5 4.1 1 1 4 5 5 5 0 HOOK protein Fib_alpha PF08702.10 EGR33726.1 - 0.082 13.1 94.7 0.058 13.6 18.3 7.4 1 1 4 6 6 6 0 Fibrinogen alpha/beta chain family ERM PF00769.19 EGR33726.1 - 0.091 12.6 87.4 0.91 9.3 16.9 5.9 1 1 4 5 5 5 0 Ezrin/radixin/moesin family DUF2576 PF10845.8 EGR33726.1 - 0.1 12.2 0.8 0.38 10.4 0.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2576) DUF812 PF05667.11 EGR33726.1 - 0.12 11.2 100.8 0.0063 15.5 34.7 4.6 1 1 4 5 5 5 0 Protein of unknown function (DUF812) Pox_A_type_inc PF04508.12 EGR33726.1 - 0.21 11.5 16.7 2.4 8.1 0.0 7.1 8 0 0 8 8 3 0 Viral A-type inclusion protein repeat DUF16 PF01519.16 EGR33726.1 - 0.24 11.9 89.3 0.085 13.4 1.9 8.3 1 1 7 8 8 7 0 Protein of unknown function DUF16 HMMR_N PF15905.5 EGR33726.1 - 0.27 10.7 105.3 0.85 9.0 14.0 4.8 1 1 3 4 4 4 0 Hyaluronan mediated motility receptor N-terminal NPV_P10 PF05531.12 EGR33726.1 - 0.35 11.4 53.6 0.65 10.5 1.7 7.6 3 2 4 7 7 7 0 Nucleopolyhedrovirus P10 protein Myosin_tail_1 PF01576.19 EGR33726.1 - 0.4 8.4 97.2 0.043 11.6 26.9 3.1 1 1 2 3 3 3 0 Myosin tail APG6_N PF17675.1 EGR33726.1 - 0.47 11.0 101.8 1.4 9.5 10.7 6.2 1 1 5 6 6 5 0 Apg6 coiled-coil region IFT57 PF10498.9 EGR33726.1 - 0.62 9.0 88.5 0.32 9.9 17.7 4.7 1 1 1 4 4 4 0 Intra-flagellar transport protein 57 HrpB7 PF09486.10 EGR33726.1 - 0.83 10.0 55.1 0.56 10.6 3.3 6.7 1 1 3 6 6 6 0 Bacterial type III secretion protein (HrpB7) CEP63 PF17045.5 EGR33726.1 - 1 9.2 99.1 0.72 9.7 35.6 5.3 1 1 4 5 5 3 0 Centrosomal protein of 63 kDa TACC_C PF05010.14 EGR33726.1 - 1.2 8.8 97.0 0.35 10.6 17.2 5.1 1 1 4 5 5 5 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal FliJ PF02050.16 EGR33726.1 - 3.1 8.0 113.5 0.41 10.9 0.8 8.5 1 1 7 8 8 8 0 Flagellar FliJ protein Desmo_N PF06771.11 EGR33726.1 - 3.9 7.9 6.3 12 6.4 0.2 3.9 3 2 1 4 4 2 0 Viral Desmoplakin N-terminus Csm1_N PF18504.1 EGR33726.1 - 3.9 7.9 89.7 2.1 8.7 3.8 11.3 3 3 8 11 11 11 0 Csm1 N-terminal domain TMPIT PF07851.13 EGR33726.1 - 4.1 6.5 74.4 0.37 10.0 11.0 5.9 1 1 3 5 5 5 0 TMPIT-like protein Uso1_p115_C PF04871.13 EGR33726.1 - 4.9 7.5 83.2 0.43 10.9 9.0 6.9 1 1 6 7 7 6 0 Uso1 / p115 like vesicle tethering protein, C terminal region RPW8 PF05659.11 EGR33726.1 - 5.4 6.7 60.6 0.34 10.6 2.9 7.2 2 2 3 6 6 6 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Sec34 PF04136.15 EGR33726.1 - 5.5 6.9 62.9 0.27 11.1 7.7 6.8 1 1 7 8 8 8 0 Sec34-like family Laminin_I PF06008.14 EGR33726.1 - 5.7 6.6 80.4 0.072 12.8 28.0 5.3 1 1 3 4 4 4 0 Laminin Domain I HemX PF04375.14 EGR33726.1 - 6.1 6.0 90.6 0.69 9.1 10.0 6.5 1 1 5 6 6 6 0 HemX, putative uroporphyrinogen-III C-methyltransferase Exonuc_VII_L PF02601.15 EGR33726.1 - 7.2 6.1 77.1 1.8 8.1 18.9 4.3 1 1 3 4 4 4 0 Exonuclease VII, large subunit FUSC PF04632.12 EGR33726.1 - 8.7 4.7 20.1 0.59 8.6 4.6 2.9 1 1 0 2 2 2 0 Fusaric acid resistance protein family Sec2p PF06428.11 EGR33726.1 - 9.8 6.2 87.5 0.33 10.9 1.1 9.4 2 2 7 9 9 9 0 GDP/GTP exchange factor Sec2p ADIP PF11559.8 EGR33727.1 - 1.4e-18 67.5 145.8 0.0025 17.9 14.7 8.9 1 1 7 8 8 8 6 Afadin- and alpha -actinin-Binding Filament PF00038.21 EGR33727.1 - 2.9e-18 66.5 141.5 1.6e-05 24.6 52.6 6.6 1 1 5 6 6 6 6 Intermediate filament protein Spc7 PF08317.11 EGR33727.1 - 1.2e-17 63.8 140.4 4.6e-06 25.7 26.4 6.9 1 1 6 7 7 7 5 Spc7 kinetochore protein AAA_13 PF13166.6 EGR33727.1 - 7.2e-17 61.3 112.7 4.7e-07 28.9 31.2 5.1 1 1 4 5 5 5 5 AAA domain DUF4201 PF13870.6 EGR33727.1 - 2.3e-15 56.8 146.1 2.1e-05 24.3 27.7 6.3 2 1 3 6 6 6 4 Domain of unknown function (DUF4201) Uso1_p115_C PF04871.13 EGR33727.1 - 1.2e-13 51.6 105.0 8.5e-06 26.2 16.8 6.7 2 1 3 6 6 6 3 Uso1 / p115 like vesicle tethering protein, C terminal region MAD PF05557.13 EGR33727.1 - 1.6e-13 49.9 142.7 0.00011 20.8 86.7 4.0 1 1 3 4 4 4 3 Mitotic checkpoint protein BLOC1_2 PF10046.9 EGR33727.1 - 4.1e-12 46.2 123.3 0.021 15.1 12.0 10.3 1 1 7 9 9 9 5 Biogenesis of lysosome-related organelles complex-1 subunit 2 Tropomyosin_1 PF12718.7 EGR33727.1 - 6.9e-12 45.7 138.8 0.0012 19.1 24.1 8.6 1 1 8 9 9 9 4 Tropomyosin like DUF1192 PF06698.11 EGR33727.1 - 1.6e-11 44.0 85.1 0.066 13.3 2.3 14.1 12 5 4 16 16 15 8 Protein of unknown function (DUF1192) GAS PF13851.6 EGR33727.1 - 5.3e-11 42.2 153.9 0.01 15.2 14.7 7.5 1 1 7 8 8 8 6 Growth-arrest specific micro-tubule binding DUF4164 PF13747.6 EGR33727.1 - 6.7e-11 42.3 101.3 0.0084 16.4 1.9 10.1 1 1 7 10 10 10 5 Domain of unknown function (DUF4164) Fib_alpha PF08702.10 EGR33727.1 - 8.1e-11 42.3 145.2 0.0022 18.2 18.6 9.2 1 1 8 9 9 9 5 Fibrinogen alpha/beta chain family DUF812 PF05667.11 EGR33727.1 - 2.8e-10 39.8 150.6 0.00063 18.8 30.0 4.7 1 1 3 4 4 4 4 Protein of unknown function (DUF812) Jnk-SapK_ap_N PF09744.9 EGR33727.1 - 1.1e-09 38.7 142.7 0.15 12.3 14.9 8.3 1 1 6 7 7 7 6 JNK_SAPK-associated protein-1 APG17 PF04108.12 EGR33727.1 - 1.3e-09 37.7 100.5 0.0015 17.7 10.3 7.2 1 1 6 7 7 7 5 Autophagy protein Apg17 DUF4200 PF13863.6 EGR33727.1 - 1.5e-09 38.2 171.3 0.041 14.3 21.5 11.3 1 1 10 11 11 11 5 Domain of unknown function (DUF4200) CENP-F_leu_zip PF10473.9 EGR33727.1 - 1.8e-09 37.8 142.5 0.0011 19.0 27.3 7.7 1 1 5 7 7 5 5 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TMF_TATA_bd PF12325.8 EGR33727.1 - 3.3e-09 36.9 136.5 0.033 14.4 8.4 9.6 1 1 8 9 9 9 4 TATA element modulatory factor 1 TATA binding EzrA PF06160.12 EGR33727.1 - 9.7e-09 33.9 128.6 0.00024 19.4 35.6 4.2 1 1 3 4 4 4 3 Septation ring formation regulator, EzrA ATG16 PF08614.11 EGR33727.1 - 9.9e-09 35.7 134.6 0.078 13.2 7.1 9.5 1 1 7 8 8 7 4 Autophagy protein 16 (ATG16) TACC_C PF05010.14 EGR33727.1 - 1.3e-08 34.9 139.9 0.15 11.9 7.8 8.9 1 1 6 7 7 7 4 Transforming acidic coiled-coil-containing protein (TACC), C-terminal SlyX PF04102.12 EGR33727.1 - 1.6e-08 35.0 161.1 0.089 13.4 4.1 13.2 2 1 11 13 13 12 5 SlyX PUB PF09409.10 EGR33727.1 - 2.9e-08 33.5 11.3 0.1 12.5 0.1 4.9 4 0 0 4 4 4 3 PUB domain TMF_DNA_bd PF12329.8 EGR33727.1 - 3e-08 33.5 144.4 0.3 11.1 9.5 12.6 1 1 14 15 15 15 7 TATA element modulatory factor 1 DNA binding FlaC_arch PF05377.11 EGR33727.1 - 3.2e-08 33.8 97.7 0.14 12.6 1.0 13.9 6 4 9 15 15 15 5 Flagella accessory protein C (FlaC) Tropomyosin PF00261.20 EGR33727.1 - 5.1e-08 32.6 122.7 0.0039 16.6 27.0 7.3 1 1 6 7 7 7 5 Tropomyosin CEP63 PF17045.5 EGR33727.1 - 2.6e-07 30.8 144.9 0.007 16.3 28.7 4.9 1 1 3 4 4 4 3 Centrosomal protein of 63 kDa HOOK PF05622.12 EGR33727.1 - 3.2e-07 28.9 136.8 5.4e-05 21.6 61.2 4.5 1 1 2 3 3 3 2 HOOK protein PspA_IM30 PF04012.12 EGR33727.1 - 3.2e-07 30.1 130.2 0.0016 18.0 3.8 11.0 1 1 7 8 8 7 3 PspA/IM30 family MscS_porin PF12795.7 EGR33727.1 - 2.9e-06 27.0 165.3 0.0025 17.4 35.9 6.0 1 1 5 6 6 6 2 Mechanosensitive ion channel porin domain TPR_MLP1_2 PF07926.12 EGR33727.1 - 4.6e-06 26.7 143.1 0.49 10.5 15.3 10.0 1 1 9 10 10 10 2 TPR/MLP1/MLP2-like protein DUF4407 PF14362.6 EGR33727.1 - 2.3e-05 23.9 101.8 3.4 6.9 21.3 7.1 1 1 3 4 4 3 0 Domain of unknown function (DUF4407) SCO1-SenC PF02630.14 EGR33727.1 - 4.7e-05 23.3 6.4 2.2 8.2 0.1 4.8 3 3 0 3 3 3 0 SCO1/SenC Ribosomal_S15 PF00312.22 EGR33727.1 - 5.1e-05 23.4 60.8 0.06 13.6 1.5 10.0 2 2 9 11 11 11 3 Ribosomal protein S15 Golgin_A5 PF09787.9 EGR33727.1 - 7.2e-05 22.4 148.1 0.05 13.1 30.3 5.1 1 1 4 5 5 5 3 Golgin subfamily A member 5 Baculo_PEP_C PF04513.12 EGR33727.1 - 0.0001 22.4 83.0 0.37 10.8 5.2 7.9 1 1 3 5 5 4 3 Baculovirus polyhedron envelope protein, PEP, C terminus DUF724 PF05266.14 EGR33727.1 - 0.00011 22.1 120.3 0.0068 16.3 18.4 8.7 1 1 10 11 11 11 5 Protein of unknown function (DUF724) ALIX_LYPXL_bnd PF13949.6 EGR33727.1 - 0.00015 21.2 113.5 0.002 17.5 33.3 4.5 1 1 3 4 4 4 2 ALIX V-shaped domain binding to HIV Fez1 PF06818.15 EGR33727.1 - 0.00034 21.1 117.3 0.46 10.9 23.4 5.5 1 1 4 5 5 5 2 Fez1 SHE3 PF17078.5 EGR33727.1 - 0.00042 20.1 120.5 0.076 12.7 44.5 5.0 1 1 3 4 4 4 3 SWI5-dependent HO expression protein 3 RasGAP_C PF03836.15 EGR33727.1 - 0.00086 19.5 13.5 0.00086 19.5 13.5 10.0 1 1 8 9 9 9 2 RasGAP C-terminus Lebercilin PF15619.6 EGR33727.1 - 0.0019 17.9 148.7 0.35 10.5 41.3 6.7 1 1 6 7 7 7 2 Ciliary protein causing Leber congenital amaurosis disease DUF1664 PF07889.12 EGR33727.1 - 0.002 18.2 101.4 0.12 12.5 6.5 9.2 1 1 8 9 9 9 5 Protein of unknown function (DUF1664) FPP PF05911.11 EGR33727.1 - 0.0025 16.1 132.3 0.037 12.2 15.8 6.9 1 1 6 7 7 7 4 Filament-like plant protein, long coiled-coil HMMR_N PF15905.5 EGR33727.1 - 0.0027 17.2 154.3 0.62 9.5 24.1 6.0 1 1 4 6 6 6 4 Hyaluronan mediated motility receptor N-terminal KN17_SH3 PF18131.1 EGR33727.1 - 0.0034 17.5 0.4 42 4.4 0.0 3.7 3 0 0 3 3 3 0 KN17 SH3-like C-terminal domain APG6_N PF17675.1 EGR33727.1 - 0.0063 17.0 151.5 0.25 11.9 16.9 8.2 1 1 7 8 8 8 2 Apg6 coiled-coil region DUF148 PF02520.17 EGR33727.1 - 0.0066 16.5 123.1 0.055 13.6 18.8 10.2 1 1 12 13 13 11 3 Domain of unknown function DUF148 BRE1 PF08647.11 EGR33727.1 - 0.007 16.4 144.6 0.17 12.0 11.9 7.9 1 1 4 7 7 7 4 BRE1 E3 ubiquitin ligase CALCOCO1 PF07888.11 EGR33727.1 - 0.0073 15.2 129.6 0.054 12.4 36.7 4.6 1 1 3 4 4 4 3 Calcium binding and coiled-coil domain (CALCOCO1) like bZIP_1 PF00170.21 EGR33727.1 - 0.0078 16.3 125.7 0.23 11.6 2.3 15.8 7 3 7 14 14 13 3 bZIP transcription factor Laminin_II PF06009.12 EGR33727.1 - 0.01 15.9 97.9 0.77 9.8 7.7 8.3 2 2 6 9 9 9 3 Laminin Domain II Fe-S_assembly PF04384.13 EGR33727.1 - 0.015 15.9 8.1 32 5.2 0.1 5.6 4 1 1 5 5 3 0 Iron-sulphur cluster assembly Leu_zip PF15294.6 EGR33727.1 - 0.016 14.7 124.6 0.012 15.2 28.6 4.9 1 1 4 5 5 5 0 Leucine zipper TSC22 PF01166.18 EGR33727.1 - 0.029 14.7 1.7 0.029 14.7 1.7 11.7 9 2 2 12 12 9 0 TSC-22/dip/bun family DHR10 PF18595.1 EGR33727.1 - 0.036 14.1 166.3 0.21 11.6 26.8 8.7 1 1 7 8 8 7 0 Designed helical repeat protein 10 domain Prefoldin_2 PF01920.20 EGR33727.1 - 0.037 14.0 158.0 0.3 11.1 20.5 12.5 2 2 4 9 9 7 0 Prefoldin subunit KASH_CCD PF14662.6 EGR33727.1 - 0.045 13.6 155.6 1.3 8.8 19.3 6.4 1 1 3 5 5 5 0 Coiled-coil region of CCDC155 or KASH MRF_C1 PF13887.6 EGR33727.1 - 0.059 12.5 9.6 20 4.4 0.1 5.7 5 0 0 5 5 4 0 Myelin gene regulatory factor -C-terminal domain 1 COG5 PF10392.9 EGR33727.1 - 0.085 13.0 87.4 0.12 12.5 9.4 8.7 1 1 7 9 9 9 0 Golgi transport complex subunit 5 Syntaxin_2 PF14523.6 EGR33727.1 - 0.087 13.2 112.3 0.71 10.3 7.5 9.6 1 1 8 9 9 9 0 Syntaxin-like protein IFT57 PF10498.9 EGR33727.1 - 0.1 11.5 137.3 0.037 13.0 17.4 6.8 1 1 6 7 7 7 0 Intra-flagellar transport protein 57 HR1 PF02185.16 EGR33727.1 - 0.1 12.7 162.7 0.27 11.4 4.8 17.9 3 3 15 18 18 17 0 Hr1 repeat LPP PF04728.13 EGR33727.1 - 0.14 12.6 74.4 5.3 7.5 0.6 14.6 5 3 11 16 16 16 0 Lipoprotein leucine-zipper FUSC PF04632.12 EGR33727.1 - 0.14 10.6 48.9 0.31 9.5 5.5 4.6 1 1 3 4 4 4 0 Fusaric acid resistance protein family GldM_N PF12081.8 EGR33727.1 - 0.14 12.2 77.6 1.1 9.3 6.3 7.5 1 1 5 7 7 7 0 GldM N-terminal domain MCPsignal PF00015.21 EGR33727.1 - 0.22 11.3 59.6 0.37 10.6 6.2 6.3 5 2 2 7 7 6 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3584 PF12128.8 EGR33727.1 - 0.29 8.6 135.5 0.17 9.4 16.7 3.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3584) HemX PF04375.14 EGR33727.1 - 0.32 10.2 131.1 0.014 14.7 12.0 8.2 1 1 7 8 8 8 0 HemX, putative uroporphyrinogen-III C-methyltransferase Rootletin PF15035.6 EGR33727.1 - 0.72 9.8 135.1 0.65 10.0 26.9 7.1 1 1 4 5 5 4 0 Ciliary rootlet component, centrosome cohesion DUF2203 PF09969.9 EGR33727.1 - 0.9 10.3 94.1 1 10.1 6.0 9.0 1 1 7 9 9 9 0 Uncharacterized conserved protein (DUF2203) OmpH PF03938.14 EGR33727.1 - 0.93 9.8 171.9 1.5 9.1 18.7 8.1 1 1 6 7 7 5 0 Outer membrane protein (OmpH-like) DUF211 PF02680.14 EGR33727.1 - 1 9.6 6.9 2.7 8.2 0.1 4.1 4 1 0 4 4 2 0 Uncharacterized ArCR, COG1888 KELK PF15796.5 EGR33727.1 - 1.4 9.4 135.7 0.22 12.0 9.4 8.7 6 3 1 8 8 8 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase FAM184 PF15665.5 EGR33727.1 - 1.5 8.6 127.4 0.009 15.8 39.1 4.9 1 1 2 3 3 2 0 Family with sequence similarity 184, A and B DMPK_coil PF08826.10 EGR33727.1 - 1.7 8.8 125.5 0.51 10.5 4.4 13.7 11 5 1 12 12 11 0 DMPK coiled coil domain like BST2 PF16716.5 EGR33727.1 - 2 9.0 139.2 0.93 10.1 5.5 13.4 4 4 9 13 13 12 0 Bone marrow stromal antigen 2 Atg14 PF10186.9 EGR33727.1 - 2.7 7.0 130.6 0.042 12.9 30.7 6.1 1 1 5 6 6 4 0 Vacuolar sorting 38 and autophagy-related subunit 14 CdvA PF18822.1 EGR33727.1 - 2.9 7.8 125.8 0.57 10.0 14.9 8.3 1 1 7 8 8 8 0 CdvA-like coiled-coil domain Myosin_tail_1 PF01576.19 EGR33727.1 - 3.1 5.5 142.3 62 1.2 64.5 4.9 1 1 2 3 3 3 0 Myosin tail Tektin PF03148.14 EGR33727.1 - 3.7 6.2 141.4 0.16 10.7 25.9 9.6 1 1 8 9 9 8 0 Tektin family Troponin PF00992.20 EGR33727.1 - 4.2 7.7 136.8 8.3 6.7 17.3 9.8 1 1 9 10 10 9 0 Troponin Prominin PF05478.11 EGR33727.1 - 4.7 5.0 96.0 0.075 11.0 26.6 3.9 1 1 3 4 4 4 0 Prominin Rab5-bind PF09311.11 EGR33727.1 - 5.3 6.3 133.7 0.18 11.2 62.7 4.1 1 1 3 4 4 4 0 Rabaptin-like protein Phage_P2_GpE PF06528.12 EGR33727.1 - 8.2 6.1 6.8 1.3e+02 2.2 0.2 3.9 3 0 0 3 3 3 0 Phage P2 GpE DUF948 PF06103.11 EGR33727.1 - 9.4 6.6 61.4 1.6 9.1 0.3 10.5 2 2 2 4 4 3 0 Bacterial protein of unknown function (DUF948) DUF1759 PF03564.15 EGR33727.1 - 9.9 6.1 78.7 1.1 9.2 5.8 8.6 1 1 7 8 8 8 0 Protein of unknown function (DUF1759) Peptidase_M3_N PF08439.10 EGR33728.1 - 0.32 11.3 4.3 0.63 10.4 0.3 3.2 3 1 1 4 4 4 0 Oligopeptidase F SCF PF02404.15 EGR33729.1 - 0.049 13.0 0.3 0.049 13.0 0.3 1.5 2 0 0 2 2 2 0 Stem cell factor Alg6_Alg8 PF03155.15 EGR33730.1 - 1e-37 130.3 13.9 1.2e-37 130.0 13.9 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Pkinase PF00069.25 EGR33731.1 - 1.8e-71 240.6 3.5 1.8e-71 240.6 3.5 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33731.1 - 1.4e-54 185.1 0.6 2e-54 184.6 0.6 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33731.1 - 2.2e-09 37.1 0.3 4.2e-07 29.6 0.0 2.5 1 1 1 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EGR33731.1 - 0.00015 20.7 0.6 0.00015 20.7 0.6 2.4 2 1 0 2 2 2 1 Fungal protein kinase TGF_beta_GS PF08515.12 EGR33731.1 - 0.1 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Transforming growth factor beta type I GS-motif Cyclin PF08613.11 EGR33732.1 - 1.3e-14 54.9 2.4 2e-14 54.3 2.4 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EGR33732.1 - 2.6e-08 33.7 0.2 2.6e-08 33.7 0.2 1.8 2 0 0 2 2 2 1 Cyclin, N-terminal domain YonK PF09642.10 EGR33732.1 - 0.038 14.1 2.4 0.06 13.5 0.1 2.6 3 0 0 3 3 3 0 YonK protein PEPCK_ATP PF01293.20 EGR33732.1 - 0.19 10.4 7.6 0.1 11.3 2.5 2.4 2 1 0 2 2 2 0 Phosphoenolpyruvate carboxykinase Band_3_cyto PF07565.13 EGR33733.1 - 2.3 8.0 11.0 4.6 7.0 11.0 1.5 1 0 0 1 1 1 0 Band 3 cytoplasmic domain CLN3 PF02487.17 EGR33733.1 - 2.6 7.0 7.3 4.4 6.3 7.3 1.5 1 0 0 1 1 1 0 CLN3 protein HECT PF00632.25 EGR33734.1 - 6.9e-61 206.4 8.2 8.9e-61 206.0 8.2 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) FHA PF00498.26 EGR33735.1 - 4.1e-26 91.1 5.1 2.1e-14 53.6 0.1 3.1 3 0 0 3 3 3 2 FHA domain Yop-YscD_cpl PF16697.5 EGR33735.1 - 1.2e-16 60.7 0.0 4e-07 30.3 0.0 2.5 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain SAM_1 PF00536.30 EGR33735.1 - 1.6e-12 47.7 0.7 7.5e-12 45.5 0.4 2.2 1 1 1 2 2 2 1 SAM domain (Sterile alpha motif) zf-C3HC4_3 PF13920.6 EGR33735.1 - 2.3e-12 46.6 18.5 4.5e-12 45.6 18.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SAM_2 PF07647.17 EGR33735.1 - 6.9e-12 45.3 1.4 2.4e-10 40.3 0.2 2.9 2 1 1 3 3 3 1 SAM domain (Sterile alpha motif) Prok-RING_4 PF14447.6 EGR33735.1 - 0.00031 20.5 17.7 0.00073 19.4 17.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 SAM_PNT PF02198.16 EGR33735.1 - 0.026 14.5 0.1 0.076 13.0 0.1 1.9 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain MU2_FHA PF18221.1 EGR33735.1 - 0.035 14.1 0.1 13 5.9 0.0 2.9 4 0 0 4 4 4 0 Mutator 2 Fork head associated domain zf-RING_5 PF14634.6 EGR33735.1 - 7.4 6.6 18.5 21 5.1 18.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain NKWYS PF10364.9 EGR33736.1 - 0.25 11.5 8.6 0.31 11.2 8.6 1.1 1 0 0 1 1 1 0 Putative capsular polysaccharide synthesis protein B9-C2 PF07162.11 EGR33738.1 - 1.1e-41 142.9 0.3 1.2e-41 142.7 0.3 1.0 1 0 0 1 1 1 1 Ciliary basal body-associated, B9 protein TCR PF03638.15 EGR33739.1 - 7.6e-24 83.7 58.9 9e-12 45.1 30.1 2.1 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain NifU PF01106.17 EGR33740.1 - 8.2e-27 93.2 1.2 1.4e-26 92.4 0.1 1.8 2 0 0 2 2 2 1 NifU-like domain Nfu_N PF08712.11 EGR33740.1 - 9.8e-18 64.0 0.4 2.3e-17 62.8 0.2 1.8 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal Guanylin PF02058.15 EGR33741.1 - 0.31 11.6 3.5 0.82 10.2 3.5 1.7 1 0 0 1 1 1 0 Guanylin precursor Phospholamban PF04272.14 EGR33741.1 - 3.3 7.3 9.0 4.3 6.9 1.1 3.8 3 0 0 3 3 3 0 Phospholamban DUF4407 PF14362.6 EGR33741.1 - 9.9 5.4 10.7 18 4.6 10.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ribosomal_L34e PF01199.18 EGR33742.1 - 3.7e-37 126.5 7.8 3.7e-37 126.5 7.8 1.6 2 0 0 2 2 2 1 Ribosomal protein L34e EGF_2 PF07974.13 EGR33745.1 - 0.00038 20.8 12.7 0.00038 20.8 12.7 4.7 4 2 0 4 4 4 1 EGF-like domain EGF_Tenascin PF18720.1 EGR33745.1 - 0.05 13.7 4.5 0.05 13.7 4.5 2.3 2 0 0 2 2 2 0 Tenascin EGF domain Peptidase_M8 PF01457.16 EGR33746.1 - 1.5e-06 27.2 8.4 0.0014 17.4 8.4 2.0 1 1 0 1 1 1 1 Leishmanolysin Peptidase_M8 PF01457.16 EGR33747.1 - 1.3e-19 70.3 0.0 1.6e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin FMN_red PF03358.15 EGR33747.1 - 0.19 11.5 0.0 22 4.8 0.0 2.2 2 0 0 2 2 2 0 NADPH-dependent FMN reductase Ank_2 PF12796.7 EGR33749.1 - 2e-13 50.7 0.0 3.1e-07 30.9 0.0 3.7 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGR33749.1 - 3.1e-12 46.8 0.2 4.1e-07 30.4 0.0 4.2 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR33749.1 - 3.8e-08 33.0 0.0 3.8 8.4 0.0 5.6 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 EGR33749.1 - 9.4e-07 29.0 0.0 0.00085 19.6 0.0 4.2 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Caldesmon PF02029.15 EGR33749.1 - 0.00023 20.1 41.8 0.00036 19.4 41.8 1.2 1 0 0 1 1 1 1 Caldesmon Dapper PF15268.6 EGR33749.1 - 0.44 9.3 28.1 0.65 8.8 28.1 1.2 1 0 0 1 1 1 0 Dapper DUF5523 PF17661.1 EGR33749.1 - 0.45 10.2 46.3 0.99 9.0 46.3 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5523) CDC27 PF09507.10 EGR33749.1 - 0.67 9.3 48.8 1.1 8.6 48.8 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 NOA36 PF06524.12 EGR33749.1 - 1.5 8.1 25.9 3.2 7.0 25.9 1.5 1 0 0 1 1 1 0 NOA36 protein DUF4045 PF13254.6 EGR33749.1 - 2.1 7.9 32.5 3.4 7.2 32.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PPP4R2 PF09184.11 EGR33749.1 - 2.1 7.8 40.5 6.9 6.2 40.5 1.8 1 0 0 1 1 1 0 PPP4R2 PHM7_cyt PF14703.6 EGR33750.1 - 0.00032 21.0 3.3 0.00032 21.0 3.3 1.5 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter TPR_21 PF09976.9 EGR33752.1 - 0.035 13.8 2.7 0.062 13.0 2.7 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain ubiquitin PF00240.23 EGR33753.1 - 3.2e-07 30.0 0.3 4.5e-07 29.5 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EGR33753.1 - 0.00053 20.4 0.8 0.003 18.0 0.8 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 EGR33753.1 - 0.083 12.7 0.4 0.12 12.3 0.4 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like p450 PF00067.22 EGR33755.1 - 9.8e-05 21.3 0.1 0.00011 21.1 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Abhydro_lipase PF04083.16 EGR33758.1 - 7.6e-18 63.8 0.3 1.4e-17 63.0 0.3 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EGR33758.1 - 1.8e-15 57.3 0.0 1.1e-14 54.7 0.1 1.9 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGR33758.1 - 0.0088 15.3 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DeoC PF01791.9 EGR33759.1 - 2.6e-19 69.8 0.2 3.7e-19 69.3 0.2 1.2 1 0 0 1 1 1 1 DeoC/LacD family aldolase Pet100 PF09803.9 EGR33760.1 - 0.12 12.9 6.4 0.076 13.5 1.4 3.2 3 0 0 3 3 3 0 Pet100 UPF0160 PF03690.13 EGR33761.1 - 9.7e-118 393.4 0.9 1.1e-117 393.2 0.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) DUF2200 PF09966.9 EGR33762.1 - 0.011 15.8 1.8 0.015 15.4 1.8 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2200) Pkinase PF00069.25 EGR33763.1 - 7.7e-33 114.0 0.2 1.5e-32 113.1 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain POLO_box PF00659.18 EGR33763.1 - 1.8e-18 66.4 1.0 5.2e-18 65.0 1.0 1.8 1 0 0 1 1 1 1 POLO box duplicated region Pkinase_Tyr PF07714.17 EGR33763.1 - 3.9e-14 52.6 0.0 7.4e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR33763.1 - 0.007 15.2 0.0 0.038 12.8 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 EGR33764.1 - 7.5e-29 100.9 1.3 3e-26 92.4 0.1 2.2 1 1 1 2 2 2 2 Protein kinase domain EF-hand_1 PF00036.32 EGR33764.1 - 1.6e-17 61.6 6.6 1.1e-08 33.9 1.2 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGR33764.1 - 1.9e-15 57.0 1.3 5.3e-15 55.6 1.3 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGR33764.1 - 2.2e-14 52.1 1.5 7.4e-07 28.6 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGR33764.1 - 2e-11 42.8 9.0 1.7e-06 27.2 0.6 2.9 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EGR33764.1 - 2.1e-10 40.3 4.3 2.2e-06 27.4 0.4 2.7 1 1 0 2 2 2 2 EF-hand domain pair Pkinase_Tyr PF07714.17 EGR33764.1 - 1.5e-06 27.7 0.1 2.6e-06 26.9 0.1 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33764.1 - 0.00025 20.5 0.0 0.00038 19.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like EF-hand_9 PF14658.6 EGR33764.1 - 0.00052 20.3 0.1 0.0017 18.6 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 EGR33764.1 - 0.0018 18.6 1.0 0.0043 17.4 1.0 1.7 1 1 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGR33764.1 - 0.0048 16.8 2.0 0.006 16.5 0.6 1.9 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand AAA_34 PF13872.6 EGR33764.1 - 0.08 11.8 0.2 0.11 11.4 0.2 1.3 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 MHC_II_beta PF00969.19 EGR33764.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Class II histocompatibility antigen, beta domain DASH_Dad4 PF08650.10 EGR33764.1 - 0.2 11.6 5.7 2.8 8.0 0.0 3.0 3 1 0 3 3 3 0 DASH complex subunit Dad4 CsgA PF17334.2 EGR33764.1 - 0.21 12.3 2.1 0.5 11.1 0.3 2.4 3 0 0 3 3 3 0 Minor curli fiber component A RabGAP-TBC PF00566.18 EGR33765.1 - 5.2e-12 45.9 4.1 5.4e-12 45.8 4.1 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain p450 PF00067.22 EGR33766.1 - 1.5e-39 136.1 0.1 1.6e-39 135.9 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 CaKB PF03185.15 EGR33767.1 - 4.9 6.8 7.1 5.9 6.5 7.1 1.0 1 0 0 1 1 1 0 Calcium-activated potassium channel, beta subunit WD40 PF00400.32 EGR33768.1 - 7.7e-27 93.0 10.0 5.2e-07 30.3 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR33768.1 - 3.5e-18 65.7 2.4 6.9e-07 29.5 0.0 4.0 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGR33768.1 - 8.6e-09 35.5 3.9 6.8e-07 29.4 1.3 2.4 2 0 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGR33768.1 - 0.0004 19.8 0.2 0.25 10.7 0.0 2.4 2 1 0 2 2 2 2 WD40-like domain IKI3 PF04762.12 EGR33768.1 - 0.0042 15.2 3.2 0.02 12.9 0.6 2.2 2 0 0 2 2 2 2 IKI3 family Pyrid_ox_like PF16242.5 EGR33768.1 - 0.062 12.9 0.1 0.13 11.8 0.1 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like DJ-1_PfpI PF01965.24 EGR33769.1 - 1.4e-38 132.3 0.1 1.6e-38 132.1 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 EGR33769.1 - 0.096 12.3 0.1 0.14 11.7 0.1 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Pkinase_Tyr PF07714.17 EGR33770.1 - 6.6e-52 176.3 0.3 7.5e-52 176.2 0.3 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGR33770.1 - 4.2e-46 157.5 0.4 5.2e-46 157.2 0.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGR33770.1 - 6e-06 25.3 0.0 8.5e-06 24.8 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGR33770.1 - 3.4e-05 23.0 0.3 5.1e-05 22.4 0.3 1.4 1 0 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGR33770.1 - 6.7e-05 22.3 0.3 0.00011 21.7 0.3 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGR33770.1 - 0.018 14.7 0.2 0.033 13.8 0.2 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EGR33770.1 - 0.069 13.1 0.1 0.35 10.8 0.1 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family MORN PF02493.20 EGR33771.1 - 1.9e-11 43.1 28.9 0.00037 20.2 1.7 4.7 5 0 0 5 5 5 4 MORN repeat SAM_2 PF07647.17 EGR33771.1 - 2.3e-10 40.4 1.8 4.3e-10 39.6 1.5 1.7 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGR33771.1 - 6e-10 39.4 1.4 1.3e-09 38.4 1.1 1.8 1 1 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 EGR33771.1 - 0.02 14.8 0.6 0.052 13.5 0.6 1.7 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain SAM_3 PF18016.1 EGR33771.1 - 0.026 14.3 3.0 0.051 13.4 0.5 2.5 2 1 1 3 3 3 0 SAM domain (Sterile alpha motif) Pkinase PF00069.25 EGR33772.1 - 5.7e-21 75.1 0.3 6.8e-21 74.8 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33772.1 - 7.4e-11 41.8 0.1 7.9e-11 41.7 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR33772.1 - 1.9e-06 28.0 0.1 2.3e-06 27.7 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGR33772.1 - 0.00023 20.1 0.1 0.00025 20.0 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR33772.1 - 0.00084 18.8 0.0 0.00095 18.6 0.0 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGR33772.1 - 0.00087 18.9 1.0 0.00091 18.9 1.0 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase RIO1 PF01163.22 EGR33772.1 - 0.0017 17.9 0.1 0.002 17.8 0.1 1.1 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 EGR33772.1 - 0.01 14.8 0.3 0.011 14.6 0.3 1.1 1 0 0 1 1 1 0 Haspin like kinase domain DNA_pol_B_palm PF14792.6 EGR33773.1 - 9.5e-31 106.4 0.2 1.7e-30 105.6 0.2 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 EGR33773.1 - 1.1e-21 76.7 0.0 2e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EGR33773.1 - 4.2e-18 64.9 1.0 9.1e-18 63.8 0.2 2.0 2 0 0 2 2 2 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 EGR33773.1 - 3.6e-13 49.7 2.7 1.5e-12 47.7 2.1 2.3 2 1 1 3 3 3 1 Helix-hairpin-helix domain HHH_5 PF14520.6 EGR33773.1 - 0.00017 22.1 0.4 0.13 12.9 0.0 2.5 2 0 0 2 2 2 2 Helix-hairpin-helix domain Methyltransf_32 PF13679.6 EGR33773.1 - 0.02 14.9 0.3 0.034 14.1 0.3 1.5 1 0 0 1 1 1 0 Methyltransferase domain NTP_transf_2 PF01909.23 EGR33773.1 - 0.026 14.8 0.0 0.093 13.0 0.0 2.0 1 1 0 1 1 1 0 Nucleotidyltransferase domain HHH_3 PF12836.7 EGR33773.1 - 0.039 14.2 0.3 3.3 8.0 0.1 2.8 2 1 0 2 2 2 0 Helix-hairpin-helix motif IMS_HHH PF11798.8 EGR33773.1 - 0.077 13.4 0.6 16 6.1 0.1 2.7 2 0 0 2 2 2 0 IMS family HHH motif HHH_2 PF12826.7 EGR33773.1 - 0.17 12.0 0.1 4.5 7.4 0.0 2.4 1 1 2 3 3 3 0 Helix-hairpin-helix motif RNA_pol_A_CTD PF03118.15 EGR33773.1 - 0.58 9.9 7.1 3 7.7 1.3 2.6 2 0 0 2 2 2 0 Bacterial RNA polymerase, alpha chain C terminal domain Ras PF00071.22 EGR33774.1 - 2.3e-55 186.6 1.5 3.3e-55 186.1 1.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR33774.1 - 3.2e-29 101.6 0.2 6.7e-29 100.5 0.2 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR33774.1 - 7.4e-11 41.8 1.0 1e-10 41.4 1.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGR33774.1 - 0.00017 21.0 1.0 0.00026 20.4 1.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGR33774.1 - 0.0032 17.5 0.0 0.0059 16.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGR33774.1 - 0.0055 16.3 0.1 0.0067 16.0 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain TMCCDC2 PF15844.5 EGR33775.1 - 3.3 7.6 13.4 0.57 10.1 9.6 1.6 1 1 1 2 2 2 0 Transmembrane and coiled-coil domain-containing protein 2 Tantalus PF15386.6 EGR33776.1 - 0.2 11.8 3.6 9.4 6.4 0.2 2.6 2 0 0 2 2 2 0 Drosophila Tantalus-like CAP PF00188.26 EGR33777.1 - 2.5e-21 76.8 0.0 6.1e-10 40.0 0.0 3.2 2 1 1 3 3 3 2 Cysteine-rich secretory protein family DUF4897 PF16238.5 EGR33777.1 - 0.73 9.7 10.1 0.56 10.0 7.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4897) ZapB PF06005.12 EGR33777.1 - 4.4 7.8 10.8 7.4 7.1 0.0 2.9 2 1 1 3 3 3 0 Cell division protein ZapB RIB43A PF05914.12 EGR33778.1 - 3.8e-11 42.4 25.6 1.8e-10 40.1 25.6 1.8 1 1 0 1 1 1 1 RIB43A DUF4320 PF14208.6 EGR33778.1 - 1.5 9.0 5.3 0.28 11.3 1.9 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4320) LptF_LptG PF03739.14 EGR33778.1 - 2.2 7.1 4.1 2.6 6.8 4.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Thiolase_N PF00108.23 EGR33778.1 - 6 6.1 6.2 3.7 6.8 2.9 1.9 1 1 1 2 2 2 0 Thiolase, N-terminal domain Pkinase_Tyr PF07714.17 EGR33779.1 - 5.1e-60 202.9 2.0 6.9e-60 202.5 2.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGR33779.1 - 1.2e-50 172.3 5.4 1.7e-50 171.9 5.4 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGR33779.1 - 1.2e-05 24.3 0.5 1.9e-05 23.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGR33779.1 - 0.0003 20.2 0.4 0.00048 19.5 0.4 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGR33779.1 - 0.0063 15.5 10.5 0.026 13.5 10.5 1.9 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EGR33779.1 - 0.039 13.6 1.6 0.11 12.0 1.6 2.0 1 1 0 1 1 1 0 RIO1 family GSG-1 PF07803.11 EGR33779.1 - 0.12 12.3 0.3 0.23 11.4 0.3 1.4 1 0 0 1 1 1 0 GSG1-like protein MORN PF02493.20 EGR33780.1 - 1.3e-17 62.6 36.4 1.9e-05 24.2 1.4 5.2 5 0 0 5 5 5 4 MORN repeat MORN_2 PF07661.13 EGR33780.1 - 0.26 11.6 16.1 4.3 7.9 0.3 4.9 3 2 1 4 4 4 0 MORN repeat variant ANAPC4_WD40 PF12894.7 EGR33781.1 - 9.7e-10 38.6 6.2 0.0034 17.6 0.0 6.5 3 1 4 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGR33781.1 - 4e-09 37.0 21.7 0.00022 21.9 0.4 6.6 8 0 0 8 8 8 4 WD domain, G-beta repeat NIF PF03031.18 EGR33782.1 - 1e-53 181.3 0.3 1.5e-53 180.8 0.3 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase MCU PF04678.13 EGR33783.1 - 0.082 13.0 12.7 0.026 14.6 3.7 3.3 2 2 0 3 3 3 0 Mitochondrial calcium uniporter Serine_rich PF08824.10 EGR33783.1 - 0.18 11.8 7.4 1.5 8.8 2.0 3.0 2 0 0 2 2 2 0 Serine rich protein interaction domain Choline_transpo PF04515.12 EGR33784.1 - 8.4e-55 186.2 18.5 8.4e-55 186.2 18.5 3.4 3 1 1 4 4 4 2 Plasma-membrane choline transporter Sigma_reg_N PF13800.6 EGR33784.1 - 0.094 13.0 0.3 0.094 13.0 0.3 3.3 4 0 0 4 4 4 0 Sigma factor regulator N-terminal Furin-like_2 PF15913.5 EGR33785.1 - 0.0022 18.1 12.0 0.0022 18.1 12.0 6.5 2 2 3 6 6 6 4 Furin-like repeat, cysteine-rich DFRP_C PF16543.5 EGR33787.1 - 1.5e-08 35.0 13.4 1.5e-08 35.0 13.4 4.9 3 2 0 4 4 4 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 EGR33787.1 - 4e-06 27.5 4.5 4e-06 27.5 4.5 4.4 2 2 2 4 4 4 2 Torus domain zf-CCCH_4 PF18044.1 EGR33787.1 - 0.0061 16.3 0.8 0.0061 16.3 0.8 2.7 2 1 0 2 2 2 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGR33787.1 - 0.03 14.4 4.6 0.03 14.4 4.6 3.2 3 0 0 3 3 3 0 Zinc finger domain Stimulus_sens_1 PF13756.6 EGR33787.1 - 0.21 12.2 2.9 3.3 8.3 0.1 2.7 3 0 0 3 3 3 0 Stimulus-sensing domain zf-CCCH_2 PF14608.6 EGR33787.1 - 0.32 11.5 11.9 3.1 8.4 2.2 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger EF-hand_13 PF17958.1 EGR33788.1 - 3.7e-34 116.4 1.0 1.3e-33 114.6 0.5 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EGR33788.1 - 1.8e-19 70.0 16.3 7.7e-15 55.1 1.8 4.3 2 2 3 5 5 5 5 EF-hand domain pair EF-hand_1 PF00036.32 EGR33788.1 - 2.8e-09 35.9 16.4 0.0046 16.4 0.2 6.3 6 0 0 6 6 6 4 EF hand EF-hand_8 PF13833.6 EGR33788.1 - 3.6e-08 33.1 8.4 0.31 10.9 0.3 5.2 4 1 0 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EGR33788.1 - 5.6e-08 32.1 15.4 0.0028 17.5 0.1 6.5 6 0 0 6 6 6 2 EF-hand domain EF-hand_5 PF13202.6 EGR33788.1 - 0.0019 17.6 6.4 0.32 10.6 0.1 4.4 4 0 0 4 4 4 2 EF hand DUF3730 PF12530.8 EGR33788.1 - 0.15 11.6 0.5 0.51 9.9 0.3 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3730) Peptidase_M41 PF01434.18 EGR33789.1 - 5.1e-57 192.8 0.0 5.1e-57 192.8 0.0 1.7 2 0 0 2 2 1 1 Peptidase family M41 AAA PF00004.29 EGR33789.1 - 7.8e-45 152.5 0.2 2.8e-44 150.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGR33789.1 - 1.3e-12 47.3 0.0 3.4e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGR33789.1 - 1.3e-05 25.0 0.0 4.6e-05 23.2 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGR33789.1 - 7.6e-05 22.1 0.1 0.0002 20.7 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_16 PF13191.6 EGR33789.1 - 9.7e-05 22.8 0.2 0.021 15.2 0.1 3.3 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 EGR33789.1 - 0.00014 21.8 0.3 0.0019 18.2 0.1 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGR33789.1 - 0.0064 16.8 3.4 0.14 12.4 0.1 3.1 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EGR33789.1 - 0.0068 16.1 0.0 0.04 13.7 0.0 2.2 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_33 PF13671.6 EGR33789.1 - 0.0085 16.3 0.1 0.084 13.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EGR33789.1 - 0.02 14.9 5.4 0.092 12.8 0.0 3.2 2 1 1 3 3 3 0 AAA domain Mg_chelatase PF01078.21 EGR33789.1 - 0.064 12.6 3.5 0.15 11.4 0.2 2.7 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGR33789.1 - 0.29 10.8 0.0 0.29 10.8 0.0 2.9 3 2 0 3 3 3 0 AAA domain AAA_25 PF13481.6 EGR33789.1 - 0.35 10.4 4.1 1.2 8.7 0.6 2.8 2 1 0 3 3 3 0 AAA domain AAA_19 PF13245.6 EGR33789.1 - 0.44 10.9 2.9 5.3 7.4 0.6 2.7 3 0 0 3 3 3 0 AAA domain AAA_11 PF13086.6 EGR33789.1 - 3.6 7.3 15.9 4.4 7.0 0.1 2.4 2 0 0 2 2 2 0 AAA domain TCR PF03638.15 EGR33791.1 - 4.3e-13 49.3 25.9 5.9e-13 48.9 25.9 1.2 1 0 0 1 1 1 1 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 EGR33791.1 - 0.8 9.9 21.5 1.9 8.7 21.5 1.7 1 1 0 1 1 1 0 CXC domain of E3 ubiquitin-protein ligase MSL2 WD40 PF00400.32 EGR33792.1 - 5.7e-05 23.8 5.4 8 7.5 0.0 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat Response_reg PF00072.24 EGR33793.1 - 0.0011 19.1 0.0 0.0072 16.5 0.0 1.9 1 1 0 1 1 1 1 Response regulator receiver domain RCC1 PF00415.18 EGR33795.1 - 0.0031 18.1 0.0 0.0071 17.0 0.0 1.7 1 0 0 1 1 1 1 Regulator of chromosome condensation (RCC1) repeat Usp PF00582.26 EGR33795.1 - 0.095 13.2 1.3 0.14 12.7 1.3 1.2 1 0 0 1 1 1 0 Universal stress protein family MORN PF02493.20 EGR33796.1 - 2.1e-84 272.6 98.4 4.7e-07 29.3 0.1 14.3 14 0 0 14 14 14 14 MORN repeat DUF3048_C PF17479.2 EGR33796.1 - 3.6 8.0 39.8 0.98 9.8 0.4 7.2 1 1 6 7 7 7 0 Protein of unknown function (DUF3048) C-terminal domain DTC PF18102.1 EGR33797.1 - 1.3e-44 151.5 0.1 1.6e-44 151.3 0.1 1.1 1 0 0 1 1 1 1 Deltex C-terminal domain Zn-C2H2_12 PF18112.1 EGR33797.1 - 0.25 11.8 0.3 0.45 11.0 0.3 1.4 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain Hydrolase_4 PF12146.8 EGR33798.1 - 4.4e-09 35.9 0.0 4.8e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR33798.1 - 1.4e-07 31.5 0.0 1.5e-07 31.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGR33798.1 - 0.00093 19.9 0.0 0.00098 19.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.11 EGR33798.1 - 0.0012 18.3 0.0 0.0081 15.5 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) PAE PF03283.13 EGR33798.1 - 0.0036 16.5 0.1 0.0042 16.2 0.1 1.1 1 0 0 1 1 1 1 Pectinacetylesterase Lipase_3 PF01764.25 EGR33798.1 - 0.0071 16.2 0.0 0.0084 16.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) RA PF00788.23 EGR33798.1 - 0.055 14.1 0.0 0.099 13.3 0.0 1.3 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain DUF1749 PF08538.10 EGR33798.1 - 0.14 11.2 0.0 0.16 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1749) Peptidase_S15 PF02129.18 EGR33798.1 - 0.16 11.6 0.0 0.17 11.4 0.0 1.1 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF809 PF05663.11 EGR33800.1 - 0.47 10.6 3.5 0.48 10.6 3.2 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF809) START PF01852.19 EGR33802.1 - 2e-09 37.2 0.0 6.8e-09 35.4 0.0 1.8 1 1 0 1 1 1 1 START domain DUF4586 PF15239.6 EGR33803.1 - 4e-08 33.8 1.0 6.2e-08 33.2 1.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Collagen PF01391.18 EGR33804.1 - 1e-08 34.8 17.4 4.1e-05 23.2 9.6 2.2 1 1 1 2 2 2 2 Collagen triple helix repeat (20 copies) Zn_Tnp_IS91 PF14319.6 EGR33804.1 - 0.15 12.1 12.4 0.038 14.0 9.1 1.7 2 0 0 2 2 2 0 Transposase zinc-binding domain DpnI PF06044.12 EGR33804.1 - 1.8 8.2 10.1 0.14 11.8 5.6 1.5 2 0 0 2 2 2 0 Dam-replacing family DUF4215 PF13948.6 EGR33804.1 - 4.4 7.8 26.4 0.1 13.1 3.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4215) FSA_C PF10479.9 EGR33804.1 - 7.2 4.6 10.5 8.8 4.3 10.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Peptidase_M8 PF01457.16 EGR33805.1 - 1.6e-18 66.7 0.0 1.8e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Leishmanolysin zf-GRF PF06839.12 EGR33805.1 - 0.045 13.9 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 GRF zinc finger DUF3797 PF12677.7 EGR33805.1 - 0.17 11.8 1.2 0.28 11.1 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3797) Peptidase_M8 PF01457.16 EGR33806.1 - 1.1e-23 83.8 13.1 1.1e-23 83.8 13.1 3.7 3 2 0 3 3 3 1 Leishmanolysin EGF_Tenascin PF18720.1 EGR33806.1 - 3.5e-08 33.3 9.2 3.5e-08 33.3 9.2 5.0 5 0 0 5 5 5 1 Tenascin EGF domain Furin-like_2 PF15913.5 EGR33806.1 - 0.00056 20.0 15.6 0.00056 20.0 15.6 9.0 2 1 6 8 8 8 2 Furin-like repeat, cysteine-rich VSP PF03302.13 EGR33806.1 - 0.0023 16.8 136.4 0.0067 15.3 21.0 5.4 1 1 4 5 5 5 3 Giardia variant-specific surface protein Myb_DNA-bind_3 PF12776.7 EGR33807.1 - 0.045 14.7 1.0 0.25 12.4 0.3 2.1 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Abi_HHR PF07815.14 EGR33807.1 - 0.058 13.6 0.1 0.15 12.3 0.1 1.8 1 1 0 1 1 1 0 Abl-interactor HHR Pkinase PF00069.25 EGR33810.1 - 5.1e-47 160.5 0.5 5.7e-47 160.3 0.5 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33810.1 - 8.8e-26 90.7 0.1 1.1e-25 90.4 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L37ae PF01780.19 EGR33811.1 - 7.7e-38 128.5 6.2 9.1e-38 128.2 6.2 1.1 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 EGR33811.1 - 0.00074 19.4 2.4 0.0014 18.6 2.4 1.5 1 0 0 1 1 1 1 Transposase zinc-ribbon domain Lar_restr_allev PF14354.6 EGR33811.1 - 0.084 13.3 1.7 0.14 12.5 1.7 1.5 1 1 0 1 1 1 0 Restriction alleviation protein Lar OrfB_Zn_ribbon PF07282.11 EGR33811.1 - 0.15 12.0 1.6 0.27 11.2 1.6 1.5 1 1 0 1 1 1 0 Putative transposase DNA-binding domain zf-BED PF02892.15 EGR33811.1 - 0.51 10.4 4.4 1.6 8.8 0.0 2.5 2 1 1 3 3 3 0 BED zinc finger Aa_trans PF01490.18 EGR33812.1 - 4.9e-06 25.5 46.3 1.3e-05 24.1 46.2 1.7 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein EF-hand_7 PF13499.6 EGR33813.1 - 7.3e-11 42.4 0.9 7.3e-11 42.4 0.9 3.0 3 1 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EGR33813.1 - 3.8e-09 35.4 3.7 4.4e-05 22.7 0.4 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGR33813.1 - 1.5e-08 33.8 0.9 0.0035 17.2 0.2 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGR33813.1 - 1.9e-08 34.0 2.9 3.6e-06 26.7 0.4 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGR33813.1 - 7.9e-07 28.3 5.8 0.0016 17.9 0.5 3.0 3 0 0 3 3 3 2 EF hand Oxysterol_BP PF01237.18 EGR33814.1 - 3.2e-37 128.3 5.8 9.1e-37 126.8 3.2 3.1 1 1 0 1 1 1 1 Oxysterol-binding protein DUF676 PF05057.14 EGR33815.1 - 8.1e-43 146.5 0.1 8.1e-43 146.5 0.1 2.0 2 0 0 2 2 2 1 Putative serine esterase (DUF676) DUF3657 PF12394.8 EGR33815.1 - 2.9e-18 66.2 1.7 2.9e-18 66.2 1.7 3.1 2 0 0 2 2 2 1 Protein FAM135 PGAP1 PF07819.13 EGR33815.1 - 0.001 18.8 0.0 0.0022 17.7 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Peptidase_C1 PF00112.23 EGR33817.1 - 2.9e-67 227.0 8.6 2.9e-67 227.0 8.6 1.7 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGR33817.1 - 9.5e-13 48.4 9.0 2e-12 47.3 9.0 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGR33817.1 - 1 8.0 6.0 2.2 7.0 0.0 2.8 3 1 0 3 3 3 0 Peptidase C1-like family Helicase_C PF00271.31 EGR33819.1 - 3.3e-30 104.7 4.0 1.5e-29 102.6 0.1 2.7 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGR33819.1 - 1.5e-16 60.6 1.5 5.1e-16 58.9 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase DUF4708 PF15813.5 EGR33819.1 - 0.046 12.9 2.3 0.45 9.6 0.2 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4708) DsbD PF02683.15 EGR33820.1 - 0.07 13.0 0.0 0.075 12.9 0.0 1.1 1 0 0 1 1 1 0 Cytochrome C biogenesis protein transmembrane region TPH PF13868.6 EGR33821.1 - 4e-05 22.3 127.5 4e-05 22.3 127.5 3.3 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain Tautomerase_2 PF14552.6 EGR33821.1 - 0.13 12.3 0.2 0.13 12.3 0.2 3.1 4 0 0 4 4 4 0 Tautomerase enzyme NIF PF03031.18 EGR33824.1 - 1.1e-44 151.9 1.9 2.6e-44 150.8 0.7 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase ABC_tran PF00005.27 EGR33825.1 - 9.2e-06 26.2 0.1 1.6e-05 25.4 0.0 1.4 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EGR33825.1 - 0.00027 20.5 0.1 0.00033 20.2 0.1 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGR33825.1 - 0.0064 16.3 0.1 0.0071 16.2 0.1 1.0 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EGR33825.1 - 0.11 12.8 0.1 0.59 10.4 0.0 2.0 1 1 1 2 2 2 0 Putative exonuclease SbcCD, C subunit DSPc PF00782.20 EGR33826.1 - 1.2e-14 54.2 0.3 3.3e-14 52.8 0.1 1.9 1 1 2 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGR33826.1 - 9.7e-05 22.0 0.2 0.00047 19.8 0.0 1.9 1 1 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EGR33826.1 - 0.019 14.9 0.0 0.032 14.2 0.0 1.4 1 1 0 1 1 1 0 Tyrosine phosphatase family CDKN3 PF05706.12 EGR33826.1 - 0.047 13.4 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) DUF4205 PF13898.6 EGR33827.1 - 9.5e-105 350.3 3.4 1.2e-104 350.0 3.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4205) Pkinase PF00069.25 EGR33828.1 - 4.6e-78 262.2 1.0 8.8e-78 261.3 1.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33828.1 - 7.2e-41 140.2 0.2 1.2e-40 139.5 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 EGR33828.1 - 1e-29 99.8 7.9 1.1e-07 30.9 0.4 4.8 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 EGR33828.1 - 5.3e-24 82.6 7.5 1.9e-05 23.9 0.1 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGR33828.1 - 2.2e-23 82.5 0.7 1.1e-11 45.0 0.3 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR33828.1 - 1.1e-22 77.9 5.7 8e-07 28.5 0.1 5.0 5 0 0 5 5 4 4 EF-hand domain EF-hand_8 PF13833.6 EGR33828.1 - 5e-12 45.5 7.1 0.0011 18.8 0.3 4.9 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGR33828.1 - 1.9e-08 34.6 0.2 0.0022 18.3 0.2 3.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kinase-like PF14531.6 EGR33828.1 - 2.2e-08 33.8 0.0 3.5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR33828.1 - 0.0025 17.2 0.1 0.0049 16.2 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGR33828.1 - 0.0033 17.0 1.3 0.035 13.7 0.4 2.4 2 0 0 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.9 EGR33828.1 - 0.021 14.3 4.5 0.035 13.6 0.0 3.1 4 0 0 4 4 4 0 PhoP regulatory network protein YrbL EF-hand_9 PF14658.6 EGR33828.1 - 0.029 14.7 0.0 0.24 11.7 0.0 2.5 2 0 0 2 2 2 0 EF-hand domain PMBR PF09373.10 EGR33828.1 - 0.034 14.3 0.6 17 5.8 0.0 4.3 4 0 0 4 4 3 0 Pseudomurein-binding repeat tRNA_synt_1c_R1 PF04558.15 EGR33828.1 - 0.057 13.4 6.8 2.8 7.9 0.0 3.9 4 0 0 4 4 4 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 APH PF01636.23 EGR33828.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family TTL PF03133.15 EGR33829.1 - 2.3e-31 109.1 12.5 1e-22 80.6 5.3 2.1 1 1 1 2 2 2 2 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR33829.1 - 1.5e-06 27.6 2.8 7e-06 25.5 0.1 2.4 2 0 0 2 2 2 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR33829.1 - 4.8e-05 22.8 3.3 0.015 14.6 0.0 2.3 2 0 0 2 2 2 2 Sugar-transfer associated ATP-grasp UPF0728 PF15092.6 EGR33829.1 - 0.012 15.4 0.6 0.034 14.0 0.3 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0728 Radial_spoke PF04712.12 EGR33830.1 - 1.2e-77 262.0 15.7 6e-59 200.3 3.1 2.1 1 1 1 2 2 2 2 Radial spokehead-like protein Ribosomal_L15e PF00827.17 EGR33830.1 - 0.32 10.7 1.5 3.5 7.3 0.1 2.2 2 0 0 2 2 2 0 Ribosomal L15 zf-CRD PF17979.1 EGR33831.1 - 0.14 12.2 0.1 0.18 11.9 0.1 1.1 1 0 0 1 1 1 0 Cysteine rich domain with multizinc binding regions Proteasome PF00227.26 EGR33832.1 - 4.7e-63 212.1 0.1 5.6e-63 211.9 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGR33832.1 - 1.8e-09 37.1 0.4 1.5e-08 34.2 0.1 2.4 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Pkinase_Tyr PF07714.17 EGR33833.1 - 1.5e-66 224.4 0.0 2.9e-66 223.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGR33833.1 - 4.7e-59 199.9 0.0 4.7e-59 199.9 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain RCC1 PF00415.18 EGR33833.1 - 2.6e-39 133.6 4.7 1.3e-08 35.3 0.0 7.7 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR33833.1 - 1.2e-33 114.1 14.1 3e-10 39.6 0.3 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat WD40_alt PF14077.6 EGR33833.1 - 0.051 13.4 1.0 0.13 12.1 1.0 1.6 1 0 0 1 1 1 0 Alternative WD40 repeat motif DUF1786 PF08735.10 EGR33833.1 - 2.2 7.5 4.8 1.3e+02 1.6 0.0 4.6 5 1 0 6 6 6 0 Putative pyruvate format-lyase activating enzyme (DUF1786) DUF4407 PF14362.6 EGR33833.1 - 2.3 7.5 5.2 4.4 6.6 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_M16 PF00675.20 EGR33835.1 - 7.2e-20 71.5 0.2 1.2e-19 70.8 0.2 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGR33835.1 - 0.002 18.2 1.3 0.064 13.3 0.3 2.2 2 0 0 2 2 2 2 Peptidase M16 inactive domain PSDC PF12588.8 EGR33835.1 - 0.11 12.5 1.4 0.41 10.6 0.2 2.1 1 1 1 2 2 2 0 Phophatidylserine decarboxylase ORF6C PF10552.9 EGR33835.1 - 0.23 11.6 2.2 11 6.2 0.4 3.1 3 1 0 3 3 3 0 ORF6C domain PPV_E1_C PF00519.17 EGR33836.1 - 0.016 14.1 0.9 0.025 13.4 0.9 1.3 1 0 0 1 1 1 0 Papillomavirus helicase Arf PF00025.21 EGR33838.1 - 1.5e-40 138.5 0.4 1.8e-39 135.0 0.1 2.5 2 0 0 2 2 2 1 ADP-ribosylation factor family Radial_spoke_3 PF06098.11 EGR33838.1 - 3.7e-38 131.5 4.7 3.7e-38 131.5 4.7 2.4 3 0 0 3 3 2 1 Radial spoke protein 3 AAA_18 PF13238.6 EGR33838.1 - 1.8e-27 96.4 4.2 1.5e-25 90.2 0.0 3.8 4 0 0 4 4 3 1 AAA domain MMR_HSR1 PF01926.23 EGR33838.1 - 3.2e-11 43.3 0.0 1.5e-07 31.5 0.0 3.3 2 0 0 2 2 2 2 50S ribosome-binding GTPase G-alpha PF00503.20 EGR33838.1 - 4.8e-11 42.4 0.0 0.0066 15.6 0.1 4.5 3 2 1 4 4 4 2 G-protein alpha subunit Roc PF08477.13 EGR33838.1 - 8.9e-10 38.8 1.3 2.5e-07 30.9 0.0 3.3 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGR33838.1 - 9.8e-09 34.9 0.1 3.2e-06 26.7 0.0 3.2 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit AAA_17 PF13207.6 EGR33838.1 - 1.1e-06 29.1 0.4 3.3e-05 24.3 0.0 3.6 5 1 0 5 5 2 1 AAA domain Ras PF00071.22 EGR33838.1 - 1e-05 25.2 0.1 0.0001 22.0 0.0 2.4 2 0 0 2 2 2 1 Ras family AAA_22 PF13401.6 EGR33838.1 - 1.1e-05 25.7 0.0 0.13 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGR33838.1 - 1.5e-05 25.5 0.0 0.0068 16.8 0.0 2.6 2 1 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGR33838.1 - 0.00032 20.7 0.1 0.87 9.5 0.0 3.5 3 0 0 3 3 3 1 RsgA GTPase AAA PF00004.29 EGR33838.1 - 0.00039 20.8 0.0 0.0016 18.9 0.0 2.1 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EGR33838.1 - 0.00088 19.2 0.6 0.0042 17.0 0.0 2.5 3 0 0 3 3 2 1 NTPase AAA_29 PF13555.6 EGR33838.1 - 0.0018 18.0 0.0 0.19 11.5 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.6 EGR33838.1 - 0.0023 18.2 0.0 0.053 13.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGR33838.1 - 0.0026 17.8 0.3 0.015 15.3 0.0 2.4 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 EGR33838.1 - 0.0028 17.1 0.0 1.3 8.3 0.0 2.6 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_24 PF13479.6 EGR33838.1 - 0.0081 15.9 0.6 0.42 10.3 0.0 3.4 3 0 0 3 3 3 1 AAA domain TniB PF05621.11 EGR33838.1 - 0.012 15.0 0.0 1.7 8.0 0.0 2.5 2 0 0 2 2 2 0 Bacterial TniB protein Mg_chelatase PF01078.21 EGR33838.1 - 0.016 14.6 0.0 0.37 10.2 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EGR33838.1 - 0.018 14.5 0.0 1.7 8.2 0.0 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_33 PF13671.6 EGR33838.1 - 0.019 15.1 0.0 1.3 9.2 0.0 3.3 2 1 1 3 3 3 0 AAA domain AAA_19 PF13245.6 EGR33838.1 - 0.021 15.1 0.2 0.086 13.2 0.0 2.1 2 0 0 2 2 1 0 AAA domain NACHT PF05729.12 EGR33838.1 - 0.024 14.6 0.0 2.7 7.9 0.0 2.6 2 0 0 2 2 2 0 NACHT domain RuvB_N PF05496.12 EGR33838.1 - 0.024 14.4 0.0 0.075 12.8 0.0 1.8 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain FeoB_N PF02421.18 EGR33838.1 - 0.034 13.7 0.6 2.4 7.7 0.1 3.2 3 1 0 3 3 2 0 Ferrous iron transport protein B Sigma54_activat PF00158.26 EGR33838.1 - 0.04 13.6 0.0 0.11 12.2 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 EGR33838.1 - 0.047 14.2 5.6 1.3 9.6 0.0 3.6 3 1 0 3 3 3 0 ABC transporter RNA_helicase PF00910.22 EGR33838.1 - 0.05 14.0 3.5 0.85 10.0 0.0 3.8 4 0 0 4 4 3 0 RNA helicase Sigma54_activ_2 PF14532.6 EGR33838.1 - 0.065 13.3 0.0 0.25 11.5 0.0 2.0 1 0 0 1 1 1 0 Sigma-54 interaction domain ADK PF00406.22 EGR33838.1 - 0.076 13.1 1.2 1.7 8.8 0.0 3.5 4 0 0 4 4 4 0 Adenylate kinase MeaB PF03308.16 EGR33838.1 - 0.2 10.6 0.0 3 6.8 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_14 PF13173.6 EGR33838.1 - 0.2 11.7 0.0 0.2 11.7 0.0 3.6 4 0 0 4 4 3 0 AAA domain Thymidylate_kin PF02223.17 EGR33838.1 - 0.99 9.1 9.1 20 4.8 0.0 5.1 5 1 1 6 6 6 0 Thymidylate kinase Ribosomal_L30 PF00327.20 EGR33839.1 - 6.1e-16 58.0 1.0 6.1e-16 58.0 1.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e Rpn3_C PF08375.11 EGR33839.1 - 0.035 14.5 0.1 0.068 13.6 0.1 1.4 1 0 0 1 1 1 0 Proteasome regulatory subunit C-terminal TPR_18 PF13512.6 EGR33839.1 - 0.21 11.7 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Kinesin PF00225.23 EGR33840.1 - 9e-39 133.3 20.6 9e-39 133.3 20.6 4.6 3 2 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EGR33840.1 - 3e-08 33.7 2.2 3e-08 33.7 2.2 6.7 4 2 0 4 4 4 1 Microtubule binding EF-hand_7 PF13499.6 EGR33841.1 - 1.7e-10 41.2 5.6 0.023 15.1 0.4 4.5 3 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EGR33841.1 - 7.7e-08 31.7 8.0 0.066 13.2 0.1 6.7 7 0 0 7 7 7 3 EF-hand domain EF-hand_1 PF00036.32 EGR33841.1 - 2.4e-07 29.8 9.8 1.1 9.0 0.0 6.5 7 0 0 7 7 7 4 EF hand EF-hand_8 PF13833.6 EGR33841.1 - 9e-06 25.4 4.7 0.011 15.5 0.0 4.7 6 0 0 6 6 6 2 EF-hand domain pair Secretin_N_2 PF07655.13 EGR33841.1 - 1.6 9.3 14.1 0.4 11.3 9.1 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain UQ_con PF00179.26 EGR33843.1 - 6.1e-20 71.3 0.2 6.9e-20 71.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGR33843.1 - 0.00012 22.4 0.7 0.00018 21.8 0.7 1.3 1 1 0 1 1 1 1 RWD domain PAS_9 PF13426.7 EGR33844.1 - 0.00015 22.0 0.2 0.00015 22.0 0.2 3.5 3 0 0 3 3 3 1 PAS domain PAS PF00989.25 EGR33844.1 - 0.0057 16.6 0.0 0.038 14.0 0.0 2.5 2 0 0 2 2 2 1 PAS fold PBP1_TM PF14812.6 EGR33844.1 - 2.5 8.6 12.3 0.43 11.0 0.1 3.4 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal URO-D PF01208.17 EGR33846.1 - 2.1e-118 395.4 0.0 2.5e-118 395.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) ABC_tran PF00005.27 EGR33847.1 - 2.7e-30 105.7 0.2 2.7e-30 105.7 0.2 1.9 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 EGR33847.1 - 3.3e-13 50.1 0.4 2.7e-07 30.7 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EGR33847.1 - 5.5e-09 35.6 33.6 5.5e-09 35.6 33.6 2.1 1 1 0 2 2 2 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EGR33847.1 - 2.3e-05 24.4 2.1 4.5e-05 23.4 2.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_15 PF13175.6 EGR33847.1 - 0.00026 20.8 7.0 0.002 17.9 1.6 3.6 2 1 2 4 4 4 2 AAA ATPase domain SMC_N PF02463.19 EGR33847.1 - 0.00032 20.2 6.0 0.085 12.3 0.1 2.9 2 1 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGR33847.1 - 0.006 16.3 0.1 0.017 14.8 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EGR33847.1 - 0.0067 16.2 0.4 2.1 8.0 0.1 2.3 2 0 0 2 2 2 2 IstB-like ATP binding protein MMR_HSR1 PF01926.23 EGR33847.1 - 0.024 14.7 0.3 0.056 13.5 0.3 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EGR33847.1 - 0.063 13.7 0.0 0.15 12.4 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_13 PF13166.6 EGR33847.1 - 0.073 11.7 12.0 0.019 13.6 1.0 3.0 2 1 1 3 3 3 0 AAA domain SbcCD_C PF13558.6 EGR33847.1 - 0.082 13.1 0.0 0.39 11.0 0.0 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit T2SSE PF00437.20 EGR33847.1 - 0.14 11.2 0.6 0.25 10.4 0.6 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Roc PF08477.13 EGR33847.1 - 0.29 11.4 0.0 0.29 11.4 0.0 2.8 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase ABC2_membrane_4 PF12730.7 EGR33847.1 - 2.6 7.9 23.3 0.16 12.0 16.5 2.3 2 1 0 2 2 2 0 ABC-2 family transporter protein DUF4378 PF14309.6 EGR33848.1 - 2.9e-08 34.3 0.6 2.9e-08 34.3 0.6 2.6 2 2 1 3 3 3 1 Domain of unknown function (DUF4378) Ribosomal_L27e PF01777.18 EGR33848.1 - 0.0018 18.6 2.1 0.0018 18.6 2.1 2.2 2 0 0 2 2 2 1 Ribosomal L27e protein family DUF1706 PF08020.11 EGR33848.1 - 0.08 12.9 0.1 0.08 12.9 0.1 2.7 3 1 0 4 4 4 0 Protein of unknown function (DUF1706) DUF2321 PF10083.9 EGR33848.1 - 0.2 11.3 0.1 0.2 11.3 0.1 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2321) DUF2624 PF11116.8 EGR33848.1 - 1.4 9.9 10.5 0.57 11.1 1.3 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2624) NIF PF03031.18 EGR33849.1 - 5e-53 179.0 3.4 5e-53 179.0 3.4 2.0 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase LAGLIDADG_WhiA PF14527.6 EGR33849.1 - 0.098 12.7 3.5 0.33 11.0 0.1 2.8 2 1 1 3 3 3 0 WhiA LAGLIDADG-like domain Ribosomal_L19 PF01245.20 EGR33851.1 - 4.6e-05 23.3 0.1 0.00019 21.4 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L19 Adaptin_N PF01602.20 EGR33852.1 - 8.5e-112 374.4 16.7 1.2e-111 373.8 16.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGR33852.1 - 2e-53 180.7 15.1 4e-53 179.8 0.2 4.5 4 1 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 EGR33852.1 - 5.7e-21 74.7 1.1 5.7e-21 74.7 1.1 2.4 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 EGR33852.1 - 7.9e-08 32.6 0.0 0.0012 19.2 0.0 4.0 3 1 0 3 3 3 1 HEAT repeats HEAT PF02985.22 EGR33852.1 - 0.00017 21.6 0.0 0.014 15.6 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat Ipi1_N PF12333.8 EGR33852.1 - 0.037 14.6 0.0 0.037 14.6 0.0 3.1 4 0 0 4 4 4 0 Rix1 complex component involved in 60S ribosome maturation DUF2235 PF09994.9 EGR33852.1 - 0.083 12.2 0.8 0.15 11.4 0.8 1.4 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) TFIIA PF03153.13 EGR33852.1 - 0.086 12.8 25.9 0.18 11.8 25.9 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3144 PF11342.8 EGR33853.1 - 0.033 14.5 0.6 0.1 12.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3144) Hemolysin_N PF12563.8 EGR33853.1 - 0.1 12.2 2.2 0.067 12.8 0.7 1.6 2 0 0 2 2 2 0 Hemolytic toxin N terminal RNA_pol_Rpb1_5 PF04998.17 EGR33854.1 - 2.6e-84 282.8 7.1 2.6e-84 282.8 7.1 3.9 2 2 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGR33854.1 - 4.5e-64 215.6 0.1 4.5e-64 215.6 0.1 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EGR33854.1 - 9.8e-33 113.3 0.4 9.8e-33 113.3 0.4 3.2 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 EGR33854.1 - 1.4e-25 90.3 39.1 5.8e-23 81.7 19.9 5.8 3 1 1 4 4 4 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 EGR33854.1 - 2.9e-21 75.4 0.2 2.9e-21 75.4 0.2 4.5 4 0 0 4 4 4 1 RNA polymerase Rpb1, domain 4 MT-A70 PF05063.14 EGR33854.1 - 0.019 14.9 2.7 5.8 6.8 1.0 3.0 3 0 0 3 3 3 0 MT-A70 DUF2220 PF09983.9 EGR33855.1 - 0.067 12.6 5.9 0.089 12.2 5.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) Pkinase PF00069.25 EGR33859.1 - 3.3e-68 229.9 0.5 6.5e-68 229.0 0.5 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33859.1 - 1.9e-41 142.1 0.1 3.1e-41 141.4 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 EGR33859.1 - 0.013 15.2 1.4 0.032 13.9 1.3 1.8 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 CBM60 PF16841.5 EGR33859.1 - 0.019 15.4 0.2 0.036 14.5 0.2 1.4 1 0 0 1 1 1 0 Ca-dependent carbohydrate-binding module xylan-binding Pkinase PF00069.25 EGR33860.1 - 1.4e-38 132.7 0.3 1.9e-38 132.3 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33860.1 - 1.1e-24 87.2 0.0 1.3e-24 86.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR33860.1 - 3.7e-06 26.0 0.0 5.4e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR33860.1 - 0.00081 18.8 0.3 0.0017 17.7 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Beta_helix PF13229.6 EGR33860.1 - 0.054 13.4 5.2 0.091 12.6 5.2 1.3 1 1 0 1 1 1 0 Right handed beta helix region Kinase-like PF14531.6 EGR33860.1 - 0.055 12.8 0.1 0.084 12.2 0.0 1.5 1 1 0 1 1 1 0 Kinase-like APH PF01636.23 EGR33860.1 - 0.22 11.4 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Adeno_terminal PF02459.15 EGR33862.1 - 6.7 5.0 9.6 7.7 4.8 9.6 1.0 1 0 0 1 1 1 0 Adenoviral DNA terminal protein TTL PF03133.15 EGR33863.1 - 3.3e-62 210.3 11.2 4.3e-62 209.9 11.2 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR33863.1 - 4.8e-10 39.1 0.3 4.5e-07 29.4 0.0 2.4 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR33863.1 - 0.00013 21.4 0.0 0.00063 19.1 0.0 2.0 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp RimK PF08443.11 EGR33863.1 - 0.0035 16.9 0.5 0.17 11.5 0.0 2.4 2 0 0 2 2 2 1 RimK-like ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGR33863.1 - 0.062 12.8 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus Bax1-I PF01027.20 EGR33864.1 - 1.9e-26 93.2 33.7 2.4e-26 92.9 33.7 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 TIP49 PF06068.13 EGR33865.1 - 2.7e-172 572.8 2.1 3.3e-172 572.5 2.1 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EGR33865.1 - 5.4e-21 74.5 0.1 1.6e-20 73.0 0.1 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EGR33865.1 - 5.9e-11 42.9 1.1 3.4e-07 30.8 0.1 2.7 2 2 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGR33865.1 - 3.1e-09 36.8 0.2 9.4e-06 25.5 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGR33865.1 - 1.5e-07 31.7 0.4 0.0033 17.7 0.1 2.7 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.6 EGR33865.1 - 3.8e-06 27.4 0.5 0.00011 22.6 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.6 EGR33865.1 - 1.9e-05 25.2 0.1 5.2e-05 23.8 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_5 PF07728.14 EGR33865.1 - 6.5e-05 22.9 0.1 0.011 15.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGR33865.1 - 0.00021 20.8 0.2 0.015 14.7 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_19 PF13245.6 EGR33865.1 - 0.001 19.4 1.7 0.75 10.1 0.4 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EGR33865.1 - 0.0016 18.0 0.1 0.0032 17.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EGR33865.1 - 0.0027 17.4 0.1 1.3 8.7 0.0 2.4 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_28 PF13521.6 EGR33865.1 - 0.0032 17.7 0.1 0.0059 16.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGR33865.1 - 0.0087 15.8 0.4 0.031 14.0 0.1 1.9 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_7 PF12775.7 EGR33865.1 - 0.01 15.4 0.1 0.04 13.4 0.0 1.9 2 0 0 2 2 2 1 P-loop containing dynein motor region ResIII PF04851.15 EGR33865.1 - 0.014 15.4 2.7 1 9.3 0.2 2.8 3 1 0 3 3 3 0 Type III restriction enzyme, res subunit Rad17 PF03215.15 EGR33865.1 - 0.026 14.4 0.1 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_11 PF13086.6 EGR33865.1 - 0.039 13.7 0.5 0.094 12.5 0.5 1.8 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGR33865.1 - 0.041 13.2 0.1 0.095 12.0 0.1 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_lid_2 PF17863.1 EGR33865.1 - 0.045 13.6 0.0 0.22 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA lid domain AAA_17 PF13207.6 EGR33865.1 - 0.05 14.0 0.7 3.5 8.0 0.0 2.7 1 1 1 2 2 2 0 AAA domain DUF2075 PF09848.9 EGR33865.1 - 0.059 12.6 0.0 0.097 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Parvo_NS1 PF01057.17 EGR33865.1 - 0.079 12.0 0.1 0.14 11.2 0.1 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_33 PF13671.6 EGR33865.1 - 0.086 13.0 0.0 0.5 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain TFIID-31kDa PF02291.15 EGR33865.1 - 0.087 12.9 0.0 0.95 9.5 0.0 2.4 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit PhoH PF02562.16 EGR33865.1 - 0.17 11.3 1.4 0.25 10.8 0.3 1.8 2 0 0 2 2 2 0 PhoH-like protein TniB PF05621.11 EGR33865.1 - 0.21 11.0 1.2 8 5.8 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein DUF2085 PF09858.9 EGR33867.1 - 0.14 12.6 0.7 0.87 10.1 0.4 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2085) DUF4199 PF13858.6 EGR33867.1 - 1 9.7 0.0 1 9.7 0.0 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) AAA PF00004.29 EGR33868.1 - 1e-36 126.3 0.0 2.1e-36 125.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGR33868.1 - 2.7e-07 30.3 0.0 5.4e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGR33868.1 - 2.7e-05 23.9 0.0 5.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGR33868.1 - 0.00011 22.4 0.2 0.005 17.1 0.1 2.7 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.6 EGR33868.1 - 0.0002 21.4 4.5 0.00052 20.1 0.0 3.2 3 2 1 4 4 4 1 AAA domain AAA_16 PF13191.6 EGR33868.1 - 0.0002 21.8 0.0 0.021 15.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EGR33868.1 - 0.00021 21.3 0.0 0.0042 17.1 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGR33868.1 - 0.00055 20.5 0.0 0.0014 19.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 EGR33868.1 - 0.00085 18.6 0.0 0.0015 17.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_24 PF13479.6 EGR33868.1 - 0.0018 18.0 0.2 0.026 14.2 0.2 2.3 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EGR33868.1 - 0.0022 18.4 0.8 0.012 16.0 0.1 2.8 2 2 0 2 2 2 1 RNA helicase TniB PF05621.11 EGR33868.1 - 0.0026 17.2 0.0 0.31 10.4 0.0 2.4 2 0 0 2 2 2 1 Bacterial TniB protein IstB_IS21 PF01695.17 EGR33868.1 - 0.0032 17.2 0.0 0.0062 16.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Parvo_NS1 PF01057.17 EGR33868.1 - 0.014 14.5 0.0 0.027 13.6 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Mg_chelatase PF01078.21 EGR33868.1 - 0.016 14.6 0.0 0.038 13.4 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Bac_DnaA PF00308.18 EGR33868.1 - 0.021 14.6 1.8 0.029 14.2 0.1 2.1 2 1 0 2 2 1 0 Bacterial dnaA protein Vps4_C PF09336.10 EGR33868.1 - 0.021 14.8 0.0 0.084 12.9 0.0 2.0 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain NACHT PF05729.12 EGR33868.1 - 0.026 14.4 0.0 0.38 10.7 0.0 2.3 1 1 1 2 2 2 0 NACHT domain ABC_tran PF00005.27 EGR33868.1 - 0.032 14.7 0.2 0.11 13.1 0.0 1.9 2 1 0 2 2 1 0 ABC transporter NB-ARC PF00931.22 EGR33868.1 - 0.041 13.1 0.0 0.1 11.8 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Roc PF08477.13 EGR33868.1 - 0.064 13.5 0.1 0.23 11.7 0.0 2.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 EGR33868.1 - 0.1 12.1 0.0 0.66 9.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGR33868.1 - 0.12 12.4 0.0 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 EGR33868.1 - 0.16 12.4 0.1 0.49 10.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.25 EGR33868.1 - 0.16 11.6 0.0 0.25 11.0 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.6 EGR33868.1 - 0.18 12.1 0.1 0.57 10.5 0.1 1.9 1 1 0 1 1 1 0 AAA domain RNA_pol PF00940.19 EGR33869.1 - 1.8e-147 491.5 4.5 6.4e-147 489.7 4.5 1.9 1 1 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EGR33869.1 - 2.6e-55 188.1 5.2 4.2e-55 187.5 5.2 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal FERM_M PF00373.18 EGR33869.1 - 0.36 11.2 0.1 0.36 11.2 0.1 2.5 4 0 0 4 4 4 0 FERM central domain DUF1492 PF07374.11 EGR33869.1 - 0.83 9.9 6.5 0.34 11.1 1.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1492) COMPASS-Shg1 PF05205.12 EGR33869.1 - 5.7 7.7 12.3 0.2 12.4 0.4 3.2 3 0 0 3 3 3 0 COMPASS (Complex proteins associated with Set1p) component shg1 DUF4203 PF13886.6 EGR33870.1 - 3.8e-07 30.0 10.0 0.0013 18.5 0.2 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4203) DUF3487 PF11990.8 EGR33870.1 - 0.51 10.2 2.1 0.69 9.8 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) Asn_synthase PF00733.21 EGR33871.1 - 4.9e-86 289.6 0.0 7.8e-49 167.2 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EGR33871.1 - 6.2e-34 116.6 0.0 1.5e-33 115.3 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGR33871.1 - 5.1e-26 91.5 0.0 1.6e-25 89.8 0.0 1.9 2 0 0 2 2 2 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EGR33871.1 - 2.3e-09 37.1 0.1 5.8e-09 35.7 0.1 1.6 1 1 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.17 EGR33871.1 - 0.012 14.7 0.0 0.024 13.8 0.0 1.5 1 0 0 1 1 1 0 NAD synthase DHHC PF01529.20 EGR33872.1 - 1.4e-22 80.2 15.4 2.1e-22 79.7 15.4 1.3 1 0 0 1 1 1 1 DHHC palmitoyltransferase Lig_C PF18330.1 EGR33872.1 - 0.05 13.6 0.3 0.072 13.1 0.3 1.2 1 0 0 1 1 1 0 Ligase Pab1020 C-terminal region IGFBP PF00219.18 EGR33872.1 - 0.6 10.8 8.4 1.1 10.0 8.4 1.4 1 0 0 1 1 1 0 Insulin-like growth factor binding protein PSI PF01437.25 EGR33872.1 - 1.2 9.8 11.7 2.9 8.5 5.2 2.8 3 0 0 3 3 3 0 Plexin repeat Hydrolase_3 PF08282.12 EGR33873.1 - 1.9 8.2 8.1 2.3 7.9 8.1 1.0 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PI3K_C2 PF00792.24 EGR33876.1 - 0.0021 18.0 4.5 0.28 11.1 0.0 3.1 3 0 0 3 3 3 2 Phosphoinositide 3-kinase C2 Gal4_dimer PF03902.13 EGR33876.1 - 0.075 13.2 0.2 0.27 11.4 0.2 2.0 1 0 0 1 1 1 0 Gal4-like dimerisation domain YscJ_FliF_C PF08345.11 EGR33876.1 - 1.2 9.5 9.7 0.079 13.3 3.2 2.3 2 0 0 2 2 2 0 Flagellar M-ring protein C-terminal Ank_2 PF12796.7 EGR33877.1 - 2.3e-55 185.1 17.0 1.2e-14 54.6 1.3 7.5 4 1 3 7 7 7 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGR33877.1 - 4.9e-52 173.7 11.6 2.1e-11 44.1 0.2 9.5 7 2 4 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGR33877.1 - 2.7e-42 142.3 11.9 1e-05 25.7 0.2 9.8 5 2 5 10 10 10 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR33877.1 - 6.5e-41 133.6 8.9 0.00016 21.8 0.1 12.3 12 0 0 12 12 12 8 Ankyrin repeat Ank PF00023.30 EGR33877.1 - 8.8e-38 127.1 13.3 0.00013 22.3 0.1 12.1 12 0 0 12 12 12 7 Ankyrin repeat BTRD1 PF17660.1 EGR33877.1 - 0.058 13.2 0.1 1.7 8.5 0.0 2.7 2 0 0 2 2 2 0 Bacterial tandem repeat domain 1 FYVE PF01363.21 EGR33878.1 - 0.15 12.2 1.6 0.42 10.8 1.6 1.7 1 0 0 1 1 1 0 FYVE zinc finger Hydrolase_4 PF12146.8 EGR33879.1 - 5.6e-16 58.5 0.0 5.3e-12 45.5 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 AXE1 PF05448.12 EGR33879.1 - 1.6e-06 27.1 0.0 0.035 12.8 0.0 2.0 1 1 0 2 2 2 2 Acetyl xylan esterase (AXE1) Abhydrolase_1 PF00561.20 EGR33879.1 - 3.2e-06 27.0 0.2 4.4e-05 23.2 0.0 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EGR33879.1 - 2.8e-05 23.9 0.0 0.0011 18.7 0.0 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) PhoPQ_related PF10142.9 EGR33879.1 - 3e-05 22.9 0.1 4e-05 22.4 0.1 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_6 PF12697.7 EGR33879.1 - 0.00035 21.2 0.0 0.00041 21.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 EGR33879.1 - 0.0097 15.6 0.0 0.019 14.6 0.0 1.4 1 1 0 1 1 1 1 Serine hydrolase (FSH1) BAAT_C PF08840.11 EGR33879.1 - 0.022 14.7 0.0 0.035 14.0 0.0 1.2 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 EGR33879.1 - 0.028 14.3 0.0 0.042 13.7 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGR33879.1 - 0.075 12.5 0.0 0.25 10.8 0.0 1.7 1 1 0 1 1 1 0 Prolyl oligopeptidase family ERO1 PF04137.15 EGR33880.1 - 1.1e-96 324.1 13.3 1.4e-96 323.8 13.3 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) RAI1 PF08652.11 EGR33880.1 - 0.065 13.4 0.1 2.6 8.3 0.0 2.5 2 0 0 2 2 2 0 RAI1 like PD-(D/E)XK nuclease SMK-1 PF04802.15 EGR33881.1 - 8.3e-05 22.5 15.2 0.0002 21.2 1.4 3.4 2 1 2 4 4 4 2 Component of IIS longevity pathway SMK-1 EF-hand_7 PF13499.6 EGR33881.1 - 0.0011 19.4 6.6 0.14 12.6 0.0 4.1 4 1 0 4 4 4 2 EF-hand domain pair LRR_4 PF12799.7 EGR33882.1 - 1.4e-14 53.9 24.9 2.1e-09 37.5 1.7 5.8 3 1 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGR33882.1 - 3e-08 33.4 17.0 3.9e-07 29.7 2.7 4.2 1 1 2 3 3 3 2 Leucine-rich repeat LRR_8 PF13855.6 EGR33882.1 - 1e-07 31.6 18.6 1.1e-05 25.1 7.6 4.3 3 1 0 3 3 3 2 Leucine rich repeat LRR_1 PF00560.33 EGR33882.1 - 0.12 13.0 8.6 19 6.3 0.0 5.2 3 2 0 3 3 3 0 Leucine Rich Repeat DUF3987 PF13148.6 EGR33882.1 - 1.8 7.5 10.6 0.11 11.5 3.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Peptidase_M8 PF01457.16 EGR33884.1 - 3.3e-27 95.4 0.1 5.2e-27 94.7 0.1 1.3 1 0 0 1 1 1 1 Leishmanolysin MFS_1 PF07690.16 EGR33885.1 - 1.4e-20 73.6 22.5 1.4e-20 73.6 22.5 2.3 2 0 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGR33885.1 - 4.6e-17 62.0 28.4 4.6e-17 62.0 28.4 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter TRI12 PF06609.13 EGR33885.1 - 2.9e-05 22.7 1.3 4.4e-05 22.1 1.3 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) VHS PF00790.19 EGR33886.1 - 2.3e-18 66.4 0.8 2.3e-18 66.4 0.8 2.1 2 0 0 2 2 2 1 VHS domain GAT PF03127.14 EGR33886.1 - 7.1e-15 55.1 10.1 7.1e-15 55.1 10.1 3.6 3 1 1 4 4 4 1 GAT domain ENTH PF01417.20 EGR33886.1 - 0.00058 19.9 1.5 0.0015 18.5 1.5 1.7 1 0 0 1 1 1 1 ENTH domain NDUF_C2 PF06374.11 EGR33887.1 - 0.051 13.7 0.4 0.16 12.1 0.1 1.8 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) PX PF00787.24 EGR33888.1 - 3.2e-19 69.0 0.4 3.2e-19 69.0 0.4 2.1 2 1 0 2 2 2 1 PX domain DUF2175 PF09943.9 EGR33888.1 - 0.019 15.2 7.2 0.39 11.0 0.0 3.6 3 1 1 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2175) CDC50 PF03381.15 EGR33889.1 - 5e-33 114.8 1.7 5.9e-33 114.6 1.7 1.0 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family 7TM_GPCR_Srt PF10321.9 EGR33889.1 - 0.028 13.4 0.2 0.031 13.3 0.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srt OAD_gamma PF04277.13 EGR33889.1 - 0.26 11.9 1.0 0.39 11.4 1.0 1.3 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain CDC50 PF03381.15 EGR33890.1 - 3.7e-42 144.8 5.9 4.7e-42 144.4 5.9 1.1 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family Pro_CA PF00484.19 EGR33891.1 - 3.3e-05 24.2 0.0 6e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Carbonic anhydrase ELFV_dehydrog_N PF02812.18 EGR33892.1 - 2.6e-40 137.3 0.0 4.3e-40 136.6 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 EGR33892.1 - 2.1e-15 57.1 0.1 1.8e-13 50.8 0.0 2.4 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Pho88 PF10032.9 EGR33892.1 - 0.014 14.7 1.1 0.059 12.6 0.8 2.0 2 0 0 2 2 2 0 Phosphate transport (Pho88) DEAD PF00270.29 EGR33893.1 - 1.6e-38 132.2 0.1 1.6e-38 132.2 0.1 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EGR33893.1 - 5.5e-10 39.5 0.0 1.5e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGR33893.1 - 2.1e-07 31.2 8.4 4.5e-06 27.0 1.9 3.3 2 2 0 3 3 3 1 Helicase conserved C-terminal domain UvrD-helicase PF00580.21 EGR33893.1 - 9.5e-06 25.3 2.9 1.6e-05 24.6 2.9 1.4 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EGR33893.1 - 0.00047 20.5 0.0 0.0011 19.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain SWI2_SNF2 PF18766.1 EGR33893.1 - 0.0041 16.8 0.3 0.0072 16.0 0.3 1.4 1 0 0 1 1 1 1 SWI2/SNF2 ATPase CMS1 PF14617.6 EGR33893.1 - 0.0094 15.3 0.8 0.013 14.9 0.0 1.6 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit sCache_like PF16736.5 EGR33893.1 - 0.013 15.6 3.4 0.025 14.7 3.4 1.5 1 0 0 1 1 1 0 Single Cache-like AAA_30 PF13604.6 EGR33893.1 - 0.022 14.5 0.0 0.04 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGR33893.1 - 0.052 13.8 0.0 0.18 12.1 0.0 1.9 1 1 0 1 1 1 0 AAA domain Sec20 PF03908.13 EGR33894.1 - 1.4e-05 24.9 1.0 2.3e-05 24.2 0.8 1.5 1 1 0 1 1 1 1 Sec20 V-SNARE_C PF12352.8 EGR33894.1 - 0.001 19.3 3.8 0.001 19.3 3.8 1.6 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF2968 PF11180.8 EGR33894.1 - 0.0016 18.1 0.8 0.0019 17.9 0.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) DUF5089 PF17002.5 EGR33894.1 - 0.0079 16.1 5.1 0.0079 16.1 5.1 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF5089) DHR10 PF18595.1 EGR33894.1 - 0.01 15.9 6.5 0.013 15.5 6.5 1.3 1 0 0 1 1 1 1 Designed helical repeat protein 10 domain HemX PF04375.14 EGR33894.1 - 0.015 14.6 4.8 0.019 14.3 4.8 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Snapin_Pallidin PF14712.6 EGR33894.1 - 0.04 14.3 3.5 0.04 14.3 3.5 2.3 1 1 1 2 2 2 0 Snapin/Pallidin Laminin_II PF06009.12 EGR33894.1 - 0.066 13.2 6.7 0.13 12.3 6.7 1.6 1 1 0 1 1 1 0 Laminin Domain II TMPIT PF07851.13 EGR33894.1 - 0.083 12.1 3.5 0.095 11.9 3.5 1.2 1 0 0 1 1 1 0 TMPIT-like protein IFT57 PF10498.9 EGR33894.1 - 0.1 11.5 9.9 0.12 11.4 9.9 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 BRE1 PF08647.11 EGR33894.1 - 0.11 12.6 14.0 0.13 12.3 0.5 2.1 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4407 PF14362.6 EGR33894.1 - 0.12 11.7 1.4 0.13 11.6 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 EGR33894.1 - 0.14 12.2 5.0 0.23 11.5 4.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) CAS_C PF12026.8 EGR33894.1 - 0.18 11.9 3.7 0.2 11.8 3.7 1.1 1 0 0 1 1 1 0 Crk-Associated Substrate C-terminal domain DUF1640 PF07798.11 EGR33894.1 - 0.33 11.0 11.7 11 6.1 11.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4709 PF15821.5 EGR33894.1 - 0.39 11.0 7.2 7.4 6.9 3.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4709) O-antigen_lig PF13425.6 EGR33894.1 - 0.52 9.1 7.0 0.62 8.8 7.0 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Tup_N PF08581.10 EGR33894.1 - 0.54 10.6 9.6 0.66 10.3 8.6 1.7 1 1 0 1 1 1 0 Tup N-terminal Med9 PF07544.13 EGR33894.1 - 1.1 9.4 10.0 1.3 9.2 5.3 2.2 1 1 1 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Exonuc_VII_L PF02601.15 EGR33894.1 - 1.6 8.2 5.8 1.7 8.1 5.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF724 PF05266.14 EGR33894.1 - 2.3 8.0 7.7 2.6 7.8 7.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF724) XhlA PF10779.9 EGR33894.1 - 3.6 7.8 15.0 1.5 9.1 4.4 2.4 1 1 1 2 2 2 0 Haemolysin XhlA Glycos_transf_3 PF00591.21 EGR33895.1 - 4.6e-22 78.8 0.2 8.3e-22 78.0 0.2 1.4 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 EGR33895.1 - 4e-20 71.4 0.3 1.4e-19 69.6 0.0 2.2 3 0 0 3 3 3 1 Glycosyl transferase family, helical bundle domain PYNP_C PF07831.13 EGR33895.1 - 3.3e-06 26.6 0.0 2.1e-05 24.1 0.0 2.2 1 1 1 2 2 2 1 Pyrimidine nucleoside phosphorylase C-terminal domain WD40 PF00400.32 EGR33896.1 - 1.9e-47 158.3 26.8 2.7e-09 37.5 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR33896.1 - 1.7e-15 57.1 0.5 0.0042 17.3 0.1 6.1 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGR33896.1 - 0.0016 17.8 0.6 0.51 9.6 0.8 2.6 1 1 1 2 2 2 2 WD40-like domain CALCOCO1 PF07888.11 EGR33896.1 - 0.0092 14.9 18.7 0.013 14.4 18.7 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like V_ATPase_I PF01496.19 EGR33896.1 - 2.6 5.8 11.0 3.4 5.5 11.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family HALZ PF02183.18 EGR33896.1 - 3.3 8.0 19.7 3.1 8.1 4.7 3.3 1 1 1 2 2 2 0 Homeobox associated leucine zipper SET PF00856.28 EGR33896.1 - 9.7 6.6 8.5 52 4.2 8.5 2.2 1 1 0 1 1 1 0 SET domain Cullin PF00888.22 EGR33897.1 - 2.4e-69 234.6 17.2 2.4e-69 234.6 17.2 1.8 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 EGR33897.1 - 5.2e-25 87.3 3.9 5.2e-25 87.3 3.9 3.7 4 1 0 4 4 4 1 Cullin protein neddylation domain SMODS PF18144.1 EGR33897.1 - 0.32 11.2 6.6 3.2 7.9 0.9 3.1 3 0 0 3 3 3 0 Second Messenger Oligonucleotide or Dinucleotide Synthetase domain Acyltransferase PF01553.21 EGR33898.1 - 0.00013 21.5 0.0 0.00021 20.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Ion_trans PF00520.31 EGR33899.1 - 1.4e-69 234.1 49.2 5.2e-42 143.8 17.7 3.1 3 0 0 3 3 3 3 Ion transport protein Sod_Fe_C PF02777.18 EGR33899.1 - 4.1 7.6 7.1 21 5.4 0.3 3.6 3 0 0 3 3 3 0 Iron/manganese superoxide dismutases, C-terminal domain ARPC4 PF05856.12 EGR33900.1 - 5.6e-11 42.3 0.1 9.4e-11 41.6 0.1 1.4 1 1 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) ASH PF15780.5 EGR33901.1 - 2.1e-11 43.9 2.0 0.00064 19.9 0.1 4.5 5 0 0 5 5 5 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Flo11 PF10182.9 EGR33901.1 - 0.21 11.7 4.9 0.091 12.9 0.8 2.5 2 1 0 2 2 2 0 Flo11 domain fn3_5 PF06280.12 EGR33901.1 - 0.67 10.7 6.1 2.9 8.6 0.2 3.7 3 1 1 4 4 4 0 Fn3-like domain LTD PF00932.19 EGR33901.1 - 7.5 7.0 6.1 5.9 7.3 0.2 3.2 3 1 0 3 3 3 0 Lamin Tail Domain Metalloenzyme PF01676.18 EGR33902.1 - 0.019 14.4 0.5 0.038 13.3 0.5 1.5 1 0 0 1 1 1 0 Metalloenzyme superfamily STAT_alpha PF01017.20 EGR33902.1 - 0.085 12.8 10.4 0.16 11.9 10.4 1.4 1 0 0 1 1 1 0 STAT protein, all-alpha domain DUF745 PF05335.13 EGR33902.1 - 0.16 11.7 0.8 0.24 11.1 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF745) eIF-4B PF06273.11 EGR33902.1 - 1.5 7.8 2.6 2 7.4 2.6 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B SRP54 PF00448.22 EGR33903.1 - 1.3e-74 250.1 0.0 2.7e-74 249.0 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EGR33903.1 - 1e-25 90.2 0.3 1e-25 90.2 0.3 3.1 3 0 0 3 3 2 1 Signal peptide binding domain SRP54_N PF02881.19 EGR33903.1 - 2e-14 53.6 6.7 5.4e-14 52.2 6.7 1.8 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_16 PF13191.6 EGR33903.1 - 9.3e-05 22.9 0.0 0.00019 21.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 EGR33903.1 - 0.00092 19.3 0.0 0.0056 16.7 0.0 2.6 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 EGR33903.1 - 0.0012 18.4 0.1 0.0043 16.7 0.1 1.9 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EGR33903.1 - 0.0013 18.9 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGR33903.1 - 0.0015 18.3 0.0 0.003 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGR33903.1 - 0.0018 17.6 0.0 0.0037 16.6 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin MeaB PF03308.16 EGR33903.1 - 0.0038 16.3 0.1 0.052 12.5 0.0 2.9 2 1 1 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ResIII PF04851.15 EGR33903.1 - 0.007 16.4 0.1 0.018 15.0 0.1 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA PF00004.29 EGR33903.1 - 0.0073 16.7 0.4 0.14 12.5 0.0 3.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGR33903.1 - 0.019 15.2 0.0 0.062 13.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGR33903.1 - 0.028 14.5 2.6 0.34 11.0 0.1 3.6 3 2 0 3 3 3 0 50S ribosome-binding GTPase AAA_17 PF13207.6 EGR33903.1 - 0.041 14.3 0.2 0.19 12.2 0.0 2.2 3 0 0 3 3 2 0 AAA domain CLP1_P PF16575.5 EGR33903.1 - 0.067 13.0 0.1 4.8 6.9 0.0 2.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop APS_kinase PF01583.20 EGR33903.1 - 0.12 12.3 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Adenylylsulphate kinase ArsA_ATPase PF02374.15 EGR33903.1 - 0.16 11.1 0.0 0.16 11.1 0.0 3.4 4 2 1 5 5 5 0 Anion-transporting ATPase Spore_Cse60 PF10957.8 EGR33903.1 - 2.7 8.1 12.0 5.3 7.1 0.6 4.1 2 2 0 3 3 3 0 Sporulation protein Cse60 EGF_Tenascin PF18720.1 EGR33904.1 - 2.4e-07 30.6 8.0 2.4e-07 30.6 8.0 5.3 5 0 0 5 5 5 1 Tenascin EGF domain Furin-like_2 PF15913.5 EGR33904.1 - 0.0026 17.9 14.9 0.0026 17.9 14.9 8.5 2 1 6 8 8 8 2 Furin-like repeat, cysteine-rich VSP PF03302.13 EGR33904.1 - 8.2 5.2 143.2 0.011 14.7 20.0 5.1 2 1 3 5 5 5 0 Giardia variant-specific surface protein Peptidase_S28 PF05577.12 EGR33905.1 - 1.6e-61 208.4 2.8 1.9e-61 208.2 2.8 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 EGR33905.1 - 0.00011 22.0 0.1 0.00018 21.2 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGR33905.1 - 0.00012 21.7 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2920 PF11144.8 EGR33905.1 - 0.00013 21.3 0.4 0.00035 19.8 0.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF2920) Peptidase_S37 PF05576.11 EGR33905.1 - 0.00022 20.1 0.1 0.00062 18.6 0.0 1.7 2 0 0 2 2 2 1 PS-10 peptidase S37 Hydrolase_4 PF12146.8 EGR33905.1 - 0.01 15.1 0.0 0.014 14.6 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 SOCS PF12610.8 EGR33905.1 - 0.072 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Suppressor of cytokine signalling MT-A70 PF05063.14 EGR33906.1 - 3e-48 164.0 0.1 4.6e-48 163.4 0.1 1.3 1 0 0 1 1 1 1 MT-A70 Pyr_redox_2 PF07992.14 EGR33907.1 - 1.2e-05 24.7 0.0 1.8e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF4275 PF14101.6 EGR33907.1 - 0.062 13.4 0.2 0.14 12.3 0.2 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4275) Enolase_C PF00113.22 EGR33909.1 - 4.4e-10 39.3 0.1 5.7e-08 32.4 0.1 2.1 1 1 0 1 1 1 1 Enolase, C-terminal TIM barrel domain HIN PF02760.15 EGR33909.1 - 0.35 10.6 2.9 0.61 9.8 2.9 1.4 1 1 0 1 1 1 0 HIN-200/IF120x domain Spy1 PF11357.8 EGR33910.1 - 0.095 13.0 3.0 0.14 12.5 3.0 1.3 1 0 0 1 1 1 0 Cell cycle regulatory protein Choline_transpo PF04515.12 EGR33911.1 - 2.7e-49 168.2 31.7 2.7e-49 168.2 31.7 2.1 2 0 0 2 2 2 1 Plasma-membrane choline transporter ETRAMP PF09716.10 EGR33912.1 - 3 7.9 8.6 5.1 7.2 8.6 1.3 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) M16C_assoc PF08367.11 EGR33914.1 - 4.9e-45 153.6 8.4 1.6e-44 152.0 8.4 1.9 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EGR33914.1 - 6.6e-19 68.6 8.4 2.6e-12 47.1 0.0 3.5 4 0 0 4 4 4 2 Peptidase M16 inactive domain DDE_3 PF13358.6 EGR33914.1 - 0.037 13.8 4.1 0.24 11.2 0.2 2.6 2 0 0 2 2 2 0 DDE superfamily endonuclease PP2C PF00481.21 EGR33915.1 - 5e-68 229.5 0.6 8.9e-68 228.7 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C Peptidase_M24 PF00557.24 EGR33915.1 - 2e-14 53.8 0.1 3.7e-14 52.9 0.1 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 PP2C_2 PF13672.6 EGR33915.1 - 0.00053 19.7 0.0 0.001 18.7 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C Helicase_C PF00271.31 EGR33916.1 - 4.1e-20 72.2 0.0 1.5e-19 70.3 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SnAC PF14619.6 EGR33916.1 - 9.9e-08 32.5 2.3 9.9e-08 32.5 2.3 3.4 3 2 0 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex MeaB PF03308.16 EGR33916.1 - 2.4 7.1 5.3 2.5 7.0 0.2 2.7 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SNF2_N PF00176.23 EGR33917.1 - 2.8e-52 177.6 0.1 2.8e-52 177.6 0.1 2.2 2 1 1 3 3 3 1 SNF2 family N-terminal domain QLQ PF08880.11 EGR33917.1 - 5.2e-08 32.5 0.4 1.5e-07 31.0 0.4 1.9 1 0 0 1 1 1 1 QLQ DEAD PF00270.29 EGR33917.1 - 8.8e-06 25.6 0.0 8.8e-06 25.6 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase HSA PF07529.13 EGR33917.1 - 4.2 7.8 26.5 0.28 11.6 20.3 2.4 2 0 0 2 2 2 0 HSA Chloroplast_duf PF14476.6 EGR33917.1 - 6.9 5.6 8.7 0.16 10.9 1.2 2.0 3 0 0 3 3 3 0 Petal formation-expressed PDR_assoc PF08370.11 EGR33918.1 - 0.037 13.8 0.3 0.037 13.8 0.3 3.5 3 0 0 3 3 3 0 Plant PDR ABC transporter associated PspB PF06667.12 EGR33918.1 - 0.7 10.0 4.8 0.58 10.3 0.1 3.5 2 0 0 2 2 2 0 Phage shock protein B TauE PF01925.19 EGR33919.1 - 3.1e-19 69.6 9.4 1.4e-09 37.9 0.2 2.1 1 1 1 2 2 2 2 Sulfite exporter TauE/SafE EF-hand_7 PF13499.6 EGR33920.1 - 9e-17 61.3 0.4 2.5e-11 43.9 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR33920.1 - 3.2e-13 48.2 2.0 0.0016 17.9 0.0 4.4 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGR33920.1 - 2.8e-12 45.5 1.9 0.00048 19.8 0.0 4.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_5 PF13202.6 EGR33920.1 - 9.1e-11 40.8 2.2 0.002 17.6 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EGR33920.1 - 1.2e-09 37.9 0.6 0.0016 18.3 0.0 3.2 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_10 PF14788.6 EGR33920.1 - 0.0034 17.2 0.1 0.058 13.3 0.0 2.4 2 0 0 2 2 2 1 EF hand LAT2 PF15703.5 EGR33920.1 - 0.0068 16.3 0.1 0.0096 15.8 0.1 1.3 1 0 0 1 1 1 1 Linker for activation of T-cells family member 2 Dockerin_1 PF00404.18 EGR33920.1 - 0.0086 16.3 0.0 0.94 9.7 0.0 2.6 2 0 0 2 2 2 1 Dockerin type I domain Peptidase_M8 PF01457.16 EGR33921.1 - 1.4e-37 129.6 11.8 1.6e-35 122.8 0.1 2.1 1 1 1 2 2 2 2 Leishmanolysin EGF_2 PF07974.13 EGR33921.1 - 0.0006 20.1 12.7 0.0006 20.1 12.7 3.1 2 0 0 2 2 2 1 EGF-like domain EGF_Tenascin PF18720.1 EGR33921.1 - 0.0013 18.7 8.2 0.0013 18.7 8.2 1.9 2 0 0 2 2 2 1 Tenascin EGF domain SprT-like PF10263.9 EGR33921.1 - 0.035 14.0 0.0 0.077 12.9 0.0 1.6 1 0 0 1 1 1 0 SprT-like family Peptidase_M91 PF14891.6 EGR33921.1 - 0.11 12.8 0.2 0.32 11.3 0.0 1.7 2 0 0 2 2 2 0 Effector protein Pkinase PF00069.25 EGR33922.1 - 3.8e-66 223.1 3.6 6.5e-66 222.4 3.6 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33922.1 - 5.3e-34 117.7 0.5 8.4e-34 117.0 0.5 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SET PF00856.28 EGR33923.1 - 2.4e-09 37.8 2.9 6.7e-09 36.4 0.1 3.0 2 2 0 2 2 2 1 SET domain Poly_export PF02563.16 EGR33923.1 - 0.087 13.1 0.1 0.25 11.6 0.1 1.7 1 0 0 1 1 1 0 Polysaccharide biosynthesis/export protein Iso_dh PF00180.20 EGR33924.1 - 1e-66 225.5 0.2 4.7e-66 223.3 0.2 1.9 1 1 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase DUF4395 PF14340.6 EGR33925.1 - 0.12 12.7 0.2 0.17 12.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4395) ArsP_2 PF11449.8 EGR33925.1 - 0.24 10.6 5.4 0.28 10.4 5.4 1.1 1 0 0 1 1 1 0 Putative, 10TM heavy-metal exporter Kinesin PF00225.23 EGR33926.1 - 6.5e-89 298.1 4.4 7.9e-89 297.9 4.4 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR33926.1 - 1.5e-26 93.1 0.6 3.1e-26 92.1 0.6 1.5 1 0 0 1 1 1 1 Microtubule binding Pkinase PF00069.25 EGR33927.1 - 2.5e-68 230.3 3.5 3.1e-68 230.0 3.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33927.1 - 4.8e-43 147.3 0.7 6e-43 147.0 0.7 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR33927.1 - 2e-07 30.6 1.2 2e-05 24.1 1.1 2.7 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGR33927.1 - 0.0025 17.2 0.4 0.0058 16.0 0.4 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR33927.1 - 0.0038 17.2 0.2 0.015 15.3 0.3 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family CH_2 PF06294.11 EGR33928.1 - 1.7e-05 24.8 0.2 1.7e-05 24.8 0.2 3.1 2 1 1 3 3 3 1 CH-like domain in sperm protein Cation_ATPase_C PF00689.21 EGR33929.1 - 1.2e-41 142.5 10.0 2.9e-41 141.2 4.2 2.4 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGR33929.1 - 1.3e-35 122.6 0.3 3.8e-35 121.1 0.3 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGR33929.1 - 3.5e-18 65.5 0.0 1.2e-17 63.7 0.0 1.9 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGR33929.1 - 1.5e-14 54.8 0.1 1.3e-07 32.2 0.0 3.5 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGR33929.1 - 2.3e-05 24.3 0.2 2.3e-05 24.3 0.2 3.4 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase SSXT PF05030.12 EGR33929.1 - 0.014 15.0 0.1 0.098 12.3 0.1 2.5 1 0 0 1 1 1 0 SSXT protein (N-terminal region) SAP18 PF06487.12 EGR33929.1 - 0.044 14.0 0.1 0.22 11.7 0.0 2.1 2 1 1 3 3 3 0 Sin3 associated polypeptide p18 (SAP18) Adhesin_E PF16747.5 EGR33929.1 - 0.05 13.7 0.9 1 9.4 0.1 2.6 2 0 0 2 2 2 0 Surface-adhesin protein E Pkinase PF00069.25 EGR33931.1 - 1.2e-63 215.0 0.8 1.4e-63 214.7 0.8 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33931.1 - 1.2e-45 155.9 0.1 1.5e-45 155.5 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR33931.1 - 9.4e-06 24.7 0.0 1.6e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGR33931.1 - 0.00099 18.5 0.0 0.0016 17.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EGR33931.1 - 0.0011 18.6 0.6 0.22 11.1 0.1 2.3 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 MORN PF02493.20 EGR33932.1 - 6.6e-44 145.2 118.6 0.00028 20.6 2.3 15.1 15 0 0 15 15 15 15 MORN repeat MORN_2 PF07661.13 EGR33932.1 - 0.00012 21.9 112.0 0.042 14.1 1.2 13.6 14 0 0 14 14 14 10 MORN repeat variant PALP PF00291.25 EGR33933.1 - 9.3e-41 140.2 0.0 1e-40 140.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DNA_pol_B_exo1 PF03104.19 EGR33934.1 - 2.5e-59 201.1 14.7 5.6e-59 200.0 14.7 1.6 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EGR33934.1 - 9.1e-16 57.6 8.4 6.2e-11 41.7 0.4 4.4 5 0 0 5 5 5 3 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EGR33934.1 - 5.7e-06 26.2 0.1 5.7e-06 26.2 0.1 2.3 2 1 0 2 2 2 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EGR33934.1 - 3.8e-05 23.7 2.6 5e-05 23.4 0.0 2.6 2 1 0 2 2 2 1 RNase_H superfamily DUF1744 PF08490.12 EGR33935.1 - 7.1e-34 117.0 7.3 9.3e-34 116.7 7.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DUF913 PF06025.12 EGR33936.1 - 0.045 12.7 4.4 0.059 12.3 4.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Prok-RING_1 PF14446.6 EGR33936.1 - 0.67 9.9 8.0 1.1 9.2 0.8 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Sec62 PF03839.16 EGR33936.1 - 6.4 6.2 8.5 9.4 5.7 8.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 zinc_ribbon_4 PF13717.6 EGR33936.1 - 7.9 6.5 8.9 5.6 7.0 0.0 3.4 4 0 0 4 4 4 0 zinc-ribbon domain LRR_6 PF13516.6 EGR33937.1 - 0.1 12.7 0.4 1.4 9.2 0.2 2.4 2 0 0 2 2 2 0 Leucine Rich repeat Pox_D5 PF03288.16 EGR33938.1 - 0.037 14.5 0.3 0.063 13.8 0.3 1.6 1 1 0 1 1 1 0 Poxvirus D5 protein-like LRR_6 PF13516.6 EGR33938.1 - 0.054 13.6 0.4 0.4 10.9 0.1 2.3 2 0 0 2 2 2 0 Leucine Rich repeat FBPase PF00316.20 EGR33939.1 - 3.3e-74 248.4 0.1 5e-74 247.9 0.1 1.3 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 EGR33939.1 - 0.00046 19.8 0.0 0.0047 16.5 0.0 2.3 3 0 0 3 3 3 1 Inositol monophosphatase family EMP24_GP25L PF01105.24 EGR33939.1 - 0.084 12.8 0.0 0.24 11.3 0.0 2.0 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Pkinase PF00069.25 EGR33940.1 - 4.2e-28 98.4 0.9 9.8e-23 80.8 0.5 2.5 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33940.1 - 4.4e-09 36.0 0.2 0.00018 20.9 0.1 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Glyoxalase PF00903.25 EGR33941.1 - 2.5e-24 85.9 1.6 9.6e-18 64.6 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGR33941.1 - 2.4e-07 31.0 0.1 0.024 14.9 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 EGR33941.1 - 0.0011 19.2 0.0 0.0023 18.1 0.0 1.5 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 EGR33941.1 - 0.0026 17.9 0.1 1.1 9.4 0.0 3.3 3 1 0 3 3 3 2 Glyoxalase-like domain PDEase_I PF00233.19 EGR33942.1 - 1.5e-76 257.3 9.9 1.5e-76 257.3 9.9 2.3 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase UPF0061 PF02696.14 EGR33942.1 - 0.0015 17.4 2.4 0.0026 16.6 2.4 1.3 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family Lipase_GDSL_3 PF14606.6 EGR33942.1 - 0.011 15.8 3.5 0.04 14.0 3.5 1.9 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family HD PF01966.22 EGR33942.1 - 0.019 15.2 1.5 0.026 14.8 0.2 1.9 2 0 0 2 2 2 0 HD domain Elongin_A PF06881.11 EGR33942.1 - 4 8.0 10.6 0.56 10.7 5.9 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Eapp_C PF10238.9 EGR33943.1 - 2.8 8.0 7.5 4.4 7.4 1.3 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein Pex26 PF07163.12 EGR33943.1 - 5.1 6.3 12.6 5 6.3 0.8 2.0 1 1 1 2 2 2 0 Pex26 protein Pkinase PF00069.25 EGR33946.1 - 9.2e-11 41.6 0.2 3.6e-08 33.1 0.0 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33946.1 - 0.0035 16.7 0.0 0.0054 16.1 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_19 PF14559.6 EGR33947.1 - 9.1e-16 58.1 0.3 6.1e-05 23.4 0.1 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGR33947.1 - 3.8e-13 49.5 3.5 0.0018 18.5 0.0 5.6 3 2 1 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGR33947.1 - 2e-12 46.2 15.9 0.022 14.8 0.1 9.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGR33947.1 - 3.1e-11 42.5 29.1 0.011 15.9 0.3 9.7 9 0 0 9 9 9 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR33947.1 - 3.9e-10 39.8 16.1 0.0034 17.6 2.3 5.1 3 1 0 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EGR33947.1 - 1.1e-09 37.6 16.9 0.015 15.1 0.2 7.8 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGR33947.1 - 3.7e-09 36.6 0.0 0.11 13.4 0.0 6.0 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGR33947.1 - 6e-09 36.4 0.0 0.0012 19.5 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EGR33947.1 - 3.4e-05 23.5 0.1 0.0061 16.2 0.0 3.5 4 0 0 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_10 PF13374.6 EGR33947.1 - 7.7e-05 22.4 1.7 19 5.3 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGR33947.1 - 9.7e-05 22.1 0.5 1.1 9.5 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGR33947.1 - 0.018 15.4 15.1 0.21 12.1 0.0 6.7 7 1 0 7 7 5 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGR33947.1 - 0.039 14.1 0.0 16 5.7 0.0 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EGR33947.1 - 0.053 12.9 1.3 6.8 5.9 0.2 2.9 3 0 0 3 3 3 0 MalT-like TPR region TPR_6 PF13174.6 EGR33947.1 - 0.19 12.5 4.5 80 4.2 0.0 5.6 5 0 0 5 5 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGR33947.1 - 0.53 10.4 15.1 3.5 7.8 0.4 4.9 5 1 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat MIT PF04212.18 EGR33947.1 - 1 9.5 7.7 0.23 11.5 0.5 3.6 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Na_H_Exchanger PF00999.21 EGR33948.1 - 3.3e-11 42.6 9.5 3.3e-11 42.6 9.5 1.4 1 1 0 1 1 1 1 Sodium/hydrogen exchanger family Spore_YhaL PF14147.6 EGR33948.1 - 0.3 10.8 5.4 7.6 6.3 0.4 3.8 2 1 0 2 2 2 0 Sporulation protein YhaL Orthopox_B11R PF07033.11 EGR33948.1 - 6.5 6.6 12.6 1.6 8.6 0.7 2.5 2 0 0 2 2 2 0 Orthopoxvirus B11R protein DHHC PF01529.20 EGR33949.1 - 8.9e-21 74.4 11.5 8.9e-21 74.4 11.5 2.3 2 0 0 2 2 2 2 DHHC palmitoyltransferase IGFBP PF00219.18 EGR33949.1 - 0.034 14.8 4.1 0.056 14.1 4.1 1.3 1 0 0 1 1 1 0 Insulin-like growth factor binding protein RecR PF02132.15 EGR33949.1 - 0.12 11.9 5.7 0.28 10.8 5.7 1.6 1 0 0 1 1 1 0 RecR protein Med27 PF11571.8 EGR33949.1 - 3.7 8.0 10.3 13 6.2 4.6 2.7 2 1 0 2 2 2 0 Mediator complex subunit 27 RIH_assoc PF08454.11 EGR33950.1 - 1.3e-20 73.1 9.9 1.3e-20 73.1 9.9 3.9 2 1 0 2 2 2 1 RyR and IP3R Homology associated UvrD-helicase PF00580.21 EGR33951.1 - 6e-22 78.6 18.5 1.3e-14 54.5 2.2 5.3 1 1 2 3 3 3 2 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EGR33951.1 - 1.3e-21 77.5 0.0 7.2e-21 75.1 0.0 2.1 2 0 0 2 2 2 1 AAA domain UvrD_C PF13361.6 EGR33951.1 - 2.1e-19 70.1 18.5 2.1e-19 70.1 18.5 3.8 2 2 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD_C_2 PF13538.6 EGR33951.1 - 3.8e-11 42.6 0.0 8.5e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 EGR33951.1 - 2.4e-07 30.7 1.7 0.0021 17.8 0.5 3.3 1 1 1 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EGR33951.1 - 6e-06 26.1 0.0 1e-05 25.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EGR33951.1 - 0.0013 18.3 1.7 0.016 14.7 1.7 2.4 1 1 0 1 1 1 1 PhoH-like protein Helicase_RecD PF05127.14 EGR33951.1 - 0.002 18.0 0.1 0.012 15.4 0.0 2.4 2 0 0 2 2 2 1 Helicase Ribosomal_S11 PF00411.19 EGR33953.1 - 2.6e-42 143.7 0.1 3.3e-42 143.3 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 PAS_9 PF13426.7 EGR33954.1 - 3.7e-05 23.9 2.0 6.9e-05 23.0 0.5 2.2 1 1 1 2 2 2 1 PAS domain PAS PF00989.25 EGR33954.1 - 0.00014 21.8 0.0 0.00032 20.7 0.0 1.7 1 0 0 1 1 1 1 PAS fold CYTL1 PF15153.6 EGR33954.1 - 0.048 13.6 0.1 0.15 12.0 0.0 1.8 2 0 0 2 2 2 0 Cytokine-like protein 1 TraE PF05309.11 EGR33954.1 - 0.053 12.9 2.3 0.078 12.4 0.5 2.0 2 0 0 2 2 2 0 TraE protein Peptidase_M8 PF01457.16 EGR33955.1 - 5.6e-34 117.7 0.0 7.3e-34 117.3 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin EGF_Tenascin PF18720.1 EGR33956.1 - 3e-05 24.0 4.6 3e-05 24.0 4.6 2.7 4 0 0 4 4 4 1 Tenascin EGF domain EGF_2 PF07974.13 EGR33956.1 - 0.00018 21.8 11.2 0.00018 21.8 11.2 2.5 3 0 0 3 3 3 1 EGF-like domain EB PF01683.18 EGR33956.1 - 0.37 11.1 14.7 1.1 9.6 13.9 2.3 1 1 0 1 1 1 0 EB module Na_H_Exchanger PF00999.21 EGR33957.1 - 8e-51 173.0 42.9 9.4e-51 172.8 42.9 1.0 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family GTP_EFTU PF00009.27 EGR33958.1 - 1.3e-41 142.3 0.0 2.6e-41 141.3 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGR33958.1 - 3.5e-25 88.1 0.0 7.4e-25 87.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EGR33958.1 - 6.4e-18 64.6 0.0 2.1e-17 62.9 0.0 2.0 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGR33958.1 - 3.4e-11 43.4 0.3 3.4e-11 43.4 0.3 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EGR33958.1 - 5.5e-08 32.8 0.0 1.3e-07 31.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II PUB PF09409.10 EGR33960.1 - 2.1e-09 37.2 0.7 3e-09 36.7 0.7 1.3 1 0 0 1 1 1 1 PUB domain Choline_transpo PF04515.12 EGR33961.1 - 1.2e-43 149.6 27.4 1.2e-43 149.6 27.4 2.7 3 0 0 3 3 3 1 Plasma-membrane choline transporter TerY_C PF15616.6 EGR33963.1 - 0.15 12.1 0.3 0.15 12.1 0.3 1.4 2 0 0 2 2 2 0 TerY-C metal binding domain PPR_2 PF13041.6 EGR33964.1 - 6.7e-37 125.5 14.9 3.5e-11 43.1 0.0 7.4 5 2 2 7 7 7 6 PPR repeat family PPR_3 PF13812.6 EGR33964.1 - 7.9e-22 77.1 22.0 3e-05 24.0 0.0 7.3 6 2 1 7 7 7 5 Pentatricopeptide repeat domain PPR_long PF17177.4 EGR33964.1 - 1.1e-20 73.9 3.5 2.7e-09 36.7 0.4 3.1 1 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EGR33964.1 - 2.3e-20 71.3 17.4 1.1e-06 28.5 0.0 8.3 8 1 0 8 8 8 5 PPR repeat PPR_1 PF12854.7 EGR33964.1 - 2.1e-14 52.9 2.1 0.0033 17.1 0.0 5.9 6 0 0 6 6 6 4 PPR repeat TPR_1 PF00515.28 EGR33964.1 - 0.0053 16.5 6.9 0.0076 16.0 0.4 4.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGR33964.1 - 3.1 8.2 5.6 12 6.3 0.6 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Ras PF00071.22 EGR33965.1 - 4.4e-51 172.7 0.9 5.6e-51 172.3 0.9 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR33965.1 - 2.3e-29 102.0 0.2 3.8e-29 101.3 0.2 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR33965.1 - 2.8e-15 56.2 0.2 4.4e-15 55.6 0.2 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGR33965.1 - 3e-07 30.1 0.7 4.4e-07 29.5 0.7 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGR33965.1 - 5.9e-07 29.6 0.0 1.1e-06 28.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGR33965.1 - 0.00021 20.8 0.1 0.00031 20.2 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EGR33965.1 - 0.00028 20.8 2.6 0.09 12.7 0.0 2.8 3 1 1 4 4 4 2 RsgA GTPase GTP_EFTU PF00009.27 EGR33965.1 - 0.00071 19.2 0.1 0.0016 18.0 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Pox_A32 PF04665.12 EGR33965.1 - 0.0036 16.8 0.2 0.012 15.0 0.0 1.9 2 1 0 2 2 2 1 Poxvirus A32 protein AAA_24 PF13479.6 EGR33965.1 - 0.015 15.1 0.3 0.025 14.3 0.3 1.8 1 1 0 1 1 1 0 AAA domain DUF1643 PF07799.12 EGR33965.1 - 0.028 14.6 1.8 2.9 8.1 0.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1643) VirE PF05272.11 EGR33965.1 - 0.051 13.3 0.5 1.8 8.2 0.0 2.3 1 1 1 2 2 2 0 Virulence-associated protein E AAA_16 PF13191.6 EGR33965.1 - 0.12 12.7 0.0 0.17 12.2 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EGR33965.1 - 0.68 10.5 4.4 5.2 7.6 4.4 2.5 1 1 0 1 1 1 0 AAA domain GCV_H PF01597.19 EGR33966.1 - 1.3e-37 128.4 0.4 1.7e-37 128.0 0.4 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 EGR33966.1 - 0.0082 16.1 0.0 0.016 15.2 0.0 1.4 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain RHH_8 PF17723.1 EGR33966.1 - 0.059 13.6 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Ribbon-Helix-Helix transcriptional regulator family Kinesin PF00225.23 EGR33967.1 - 7.6e-95 317.6 8.7 7.6e-95 317.6 8.7 2.4 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EGR33967.1 - 9.6e-21 74.3 0.5 9.6e-21 74.3 0.5 3.7 4 1 1 5 5 5 1 Microtubule binding SIS PF01380.22 EGR33967.1 - 0.13 12.1 0.9 2.8 7.8 0.1 2.5 1 1 1 2 2 2 0 SIS domain Peptidase_M8 PF01457.16 EGR33968.1 - 9.2e-41 140.1 10.7 6.7e-37 127.4 0.0 3.5 1 1 3 4 4 4 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR33968.1 - 0.00019 21.4 3.9 0.00019 21.4 3.9 4.2 4 0 0 4 4 4 1 Tenascin EGF domain Furin-like_2 PF15913.5 EGR33968.1 - 0.0021 18.2 9.8 0.0021 18.2 9.8 7.1 1 1 5 6 6 6 3 Furin-like repeat, cysteine-rich Tai4 PF16695.5 EGR33969.1 - 0.34 11.4 2.2 1 9.9 0.0 2.8 3 0 0 3 3 3 0 Type VI secretion system (T6SS), amidase immunity protein SPA PF08616.10 EGR33970.1 - 1.8e-06 27.9 2.7 3.3e-06 27.0 0.9 2.3 1 1 1 2 2 2 1 Stabilization of polarity axis DNA_ligase_A_M PF01068.21 EGR33971.1 - 9.4e-64 214.8 1.7 9.4e-64 214.8 1.7 2.4 2 0 0 2 2 2 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGR33971.1 - 2.6e-35 122.3 0.5 7.1e-35 120.9 0.5 1.8 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EGR33971.1 - 1.9e-21 76.5 0.0 1e-20 74.1 0.0 2.3 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region PcfJ PF14284.6 EGR33971.1 - 0.073 12.9 4.6 0.2 11.5 0.2 2.7 2 0 0 2 2 2 0 PcfJ-like protein Peptidase_M8 PF01457.16 EGR33972.1 - 2.4e-40 138.7 8.7 3.5e-39 134.9 8.7 2.0 1 1 0 1 1 1 1 Leishmanolysin EGF_Tenascin PF18720.1 EGR33972.1 - 0.0024 17.9 4.4 0.0024 17.9 4.4 2.3 2 0 0 2 2 2 1 Tenascin EGF domain Peptidase_M10 PF00413.24 EGR33972.1 - 0.041 13.7 0.1 0.067 13.0 0.1 1.3 1 0 0 1 1 1 0 Matrixin SprT-like PF10263.9 EGR33972.1 - 0.11 12.4 0.1 0.22 11.4 0.1 1.5 1 0 0 1 1 1 0 SprT-like family Mito_carr PF00153.27 EGR33973.1 - 4.9e-36 122.6 0.9 2.6e-19 69.0 0.1 2.0 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF2315 PF10231.9 EGR33973.1 - 0.094 12.8 1.0 0.95 9.6 0.2 2.2 2 0 0 2 2 2 0 Apoptogenic protein 1 Choline_transpo PF04515.12 EGR33974.1 - 2.8e-64 217.4 24.6 2.8e-64 217.4 24.6 2.5 3 0 0 3 3 3 1 Plasma-membrane choline transporter CitMHS PF03600.16 EGR33974.1 - 0.076 12.2 0.0 1.5 8.0 0.0 2.2 1 1 1 2 2 2 0 Citrate transporter Pex24p PF06398.11 EGR33974.1 - 0.2 10.6 7.9 4.1 6.3 4.6 2.9 2 1 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF373 PF04123.13 EGR33974.1 - 5.8 6.2 14.5 0.3 10.5 8.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF373) Pkinase PF00069.25 EGR33977.1 - 2.6e-37 128.6 1.8 8.2e-25 87.7 0.0 2.4 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR33977.1 - 3.8e-14 52.6 0.1 4.4e-09 36.0 0.0 2.4 2 1 1 3 3 3 2 Protein tyrosine kinase DUF4550 PF15084.6 EGR33977.1 - 0.013 15.9 1.3 0.023 15.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4550) Cnd1 PF12717.7 EGR33977.1 - 0.21 11.6 5.4 0.092 12.8 2.5 1.9 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 E1-E2_ATPase PF00122.20 EGR33978.1 - 3.4e-37 127.7 1.0 3.4e-37 127.7 1.0 2.5 4 0 0 4 4 4 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGR33978.1 - 4.3e-36 124.3 11.0 4.3e-36 124.3 11.0 2.3 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGR33978.1 - 2.6e-21 75.5 0.3 9.3e-21 73.7 0.1 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGR33978.1 - 6.5e-13 49.4 0.8 6.9e-07 29.8 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGR33978.1 - 2.1e-11 43.4 0.9 7.2e-11 41.6 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGR33978.1 - 0.00084 19.1 12.4 0.0014 18.5 0.6 3.5 3 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase MMS1_N PF10433.9 EGR33979.1 - 4.5e-147 490.6 0.6 8.4e-147 489.7 0.6 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGR33979.1 - 4.1e-65 220.2 0.2 7.5e-63 212.8 0.0 3.1 2 1 1 3 3 3 1 CPSF A subunit region WD40_like PF17005.5 EGR33979.1 - 0.0009 18.7 5.0 0.025 13.9 1.1 3.5 2 2 1 3 3 3 1 WD40-like domain ANAPC4_WD40 PF12894.7 EGR33979.1 - 0.0051 17.1 0.0 0.051 13.9 0.0 2.7 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Angiomotin_C PF12240.8 EGR33979.1 - 0.14 11.7 0.4 16 4.9 0.1 2.3 2 0 0 2 2 2 0 Angiomotin C terminal Methyltrans_SAM PF10672.9 EGR33981.1 - 0.053 12.7 0.1 0.056 12.6 0.1 1.1 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase MS_channel PF00924.18 EGR33981.1 - 0.077 12.5 0.1 0.089 12.3 0.1 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel ProRS-C_1 PF09180.11 EGR33982.1 - 1.9e-23 82.5 1.0 5.5e-23 81.0 0.4 2.3 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 EGR33982.1 - 5.5e-20 72.1 0.0 1.9e-19 70.3 0.0 1.9 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA_edit PF04073.15 EGR33982.1 - 2.8e-19 69.4 0.0 5.1e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Aminoacyl-tRNA editing domain HGTP_anticodon PF03129.20 EGR33982.1 - 3.4e-16 59.2 0.0 9.7e-16 57.7 0.0 1.8 1 0 0 1 1 1 1 Anticodon binding domain PH PF00169.29 EGR33982.1 - 0.06 13.9 1.2 0.18 12.3 1.2 1.9 1 0 0 1 1 1 0 PH domain DAN PF03045.15 EGR33982.1 - 0.23 11.5 1.9 0.58 10.2 1.9 1.7 1 0 0 1 1 1 0 DAN domain PsbU PF06514.11 EGR33982.1 - 0.26 11.3 2.0 0.45 10.5 0.1 2.3 2 0 0 2 2 2 0 Photosystem II 12 kDa extrinsic protein (PsbU) Response_reg PF00072.24 EGR33983.1 - 1.6e-08 34.7 0.1 1.9e-08 34.5 0.1 1.0 1 0 0 1 1 1 1 Response regulator receiver domain RPN1_RPN2_N PF17781.1 EGR33984.1 - 8.7e-106 353.8 16.9 8.7e-106 353.8 16.9 1.6 2 0 0 2 2 2 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EGR33984.1 - 1.3e-29 102.0 0.0 3.3e-29 100.7 0.0 1.7 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EGR33984.1 - 1.1e-18 66.7 18.1 1.6e-06 28.2 0.2 8.8 9 0 0 9 9 9 3 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EGR33984.1 - 2.7e-06 27.6 1.4 0.032 14.6 0.0 4.0 4 1 2 6 6 6 3 HEAT repeats Rubredoxin_C PF18267.1 EGR33984.1 - 0.087 12.8 0.3 0.56 10.2 0.0 2.5 3 0 0 3 3 3 0 Rubredoxin NAD+ reductase C-terminal domain Utp13 PF08625.11 EGR33984.1 - 0.23 11.3 7.1 0.34 10.8 0.1 3.5 3 0 0 3 3 3 0 Utp13 specific WD40 associated domain FAM76 PF16046.5 EGR33984.1 - 1.8 7.9 7.0 3.5 6.9 7.0 1.5 1 0 0 1 1 1 0 FAM76 protein Nnf1 PF03980.14 EGR33984.1 - 9.7 6.6 10.4 2.1 8.8 0.1 3.1 3 0 0 3 3 3 0 Nnf1 DSPc PF00782.20 EGR33986.1 - 0.0037 17.1 1.3 0.0051 16.6 1.3 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Hydrolase_4 PF12146.8 EGR33987.1 - 3.8e-08 32.9 0.0 4.3e-08 32.7 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR33987.1 - 0.00012 21.8 0.0 0.00012 21.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGR33987.1 - 0.0019 17.7 0.0 0.0021 17.5 0.0 1.0 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EGR33987.1 - 0.0027 17.3 0.0 0.0029 17.2 0.0 1.0 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.7 EGR33987.1 - 0.013 15.2 0.0 0.015 15.1 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 EGR33987.1 - 0.024 14.3 0.0 0.024 14.3 0.0 1.1 1 0 0 1 1 1 0 PGAP1-like protein DUF915 PF06028.11 EGR33987.1 - 0.036 13.4 0.0 0.037 13.3 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) BAAT_C PF08840.11 EGR33987.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 EGR33987.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Dienelactone hydrolase family Esterase PF00756.20 EGR33987.1 - 0.17 11.5 0.0 0.17 11.5 0.0 1.1 1 0 0 1 1 1 0 Putative esterase Peptidase_M8 PF01457.16 EGR33988.1 - 3.1e-16 59.2 16.1 2.3e-12 46.4 1.8 2.2 1 1 1 2 2 2 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR33988.1 - 4.6e-05 23.3 2.3 4.6e-05 23.3 2.3 2.5 2 0 0 2 2 2 1 Tenascin EGF domain EGF_2 PF07974.13 EGR33988.1 - 0.00089 19.6 13.7 0.00089 19.6 13.7 4.0 4 0 0 4 4 4 1 EGF-like domain Peptidase_M8 PF01457.16 EGR33990.1 - 1.8e-41 142.4 16.9 3.4e-40 138.2 12.5 2.7 2 1 0 2 2 2 1 Leishmanolysin EGF_Tenascin PF18720.1 EGR33990.1 - 2.4e-05 24.3 1.4 2.4e-05 24.3 1.4 2.7 3 0 0 3 3 3 1 Tenascin EGF domain Fer4_23 PF18009.1 EGR33990.1 - 0.088 13.2 0.5 31 5.1 0.0 3.4 2 1 1 3 3 3 0 4Fe-4S iron-sulfur cluster binding domain PPARgamma_N PF12577.8 EGR33990.1 - 0.21 12.3 1.2 10 6.9 0.0 2.6 2 0 0 2 2 2 0 PPAR gamma N-terminal region Sugar_tr PF00083.24 EGR33992.1 - 9.1e-74 248.9 23.6 4.5e-38 131.3 1.2 2.0 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGR33992.1 - 4e-14 52.3 12.5 1.1e-12 47.6 7.8 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 EGR33992.1 - 0.024 15.2 1.6 0.024 15.2 1.6 2.4 2 0 0 2 2 2 0 Phage holin family 2 DUF5321 PF17254.2 EGR33992.1 - 0.41 10.1 5.0 0.97 8.8 5.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5321) GED PF02212.18 EGR33992.1 - 0.51 10.5 4.6 6.5 7.0 0.1 2.8 2 0 0 2 2 2 0 Dynamin GTPase effector domain Peptidase_M8 PF01457.16 EGR33994.1 - 1.9e-41 142.4 11.1 4.4e-39 134.6 0.2 4.1 2 2 2 4 4 4 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR33994.1 - 8.3e-07 28.9 11.8 8.3e-07 28.9 11.8 5.3 5 1 0 5 5 5 1 Tenascin EGF domain Furin-like_2 PF15913.5 EGR33994.1 - 0.00074 19.6 20.9 0.00074 19.6 20.9 7.4 2 1 5 8 8 8 2 Furin-like repeat, cysteine-rich EGF_2 PF07974.13 EGR33994.1 - 0.0019 18.5 13.7 0.0019 18.5 13.7 8.6 7 4 2 9 9 9 1 EGF-like domain GF_recep_IV PF14843.6 EGR33994.1 - 0.012 15.4 29.5 0.012 15.4 29.5 5.8 1 1 5 6 6 6 0 Growth factor receptor domain IV Peptidase_M8 PF01457.16 EGR33995.1 - 2.9e-45 155.0 8.4 2.3e-42 145.4 0.1 4.7 2 2 2 4 4 4 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR33995.1 - 1.8e-06 27.8 8.0 1.8e-06 27.8 8.0 6.3 6 0 0 6 6 6 1 Tenascin EGF domain Furin-like_2 PF15913.5 EGR33995.1 - 0.00084 19.5 13.7 0.00084 19.5 13.7 9.4 2 1 7 10 10 10 2 Furin-like repeat, cysteine-rich VSP PF03302.13 EGR33995.1 - 0.37 9.6 158.9 0.014 14.3 24.6 6.2 1 1 4 6 6 6 0 Giardia variant-specific surface protein Peptidase_M8 PF01457.16 EGR33996.1 - 1.4e-40 139.5 7.0 1.6e-38 132.7 0.1 4.7 2 2 1 3 3 3 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR33996.1 - 2.5e-06 27.4 12.5 2.5e-06 27.4 12.5 6.0 6 1 0 6 6 6 1 Tenascin EGF domain Furin-like_2 PF15913.5 EGR33996.1 - 0.00081 19.5 14.0 0.00081 19.5 14.0 9.2 2 1 6 8 8 8 2 Furin-like repeat, cysteine-rich Peptidase_M8 PF01457.16 EGR33997.1 - 1e-41 143.3 9.3 1e-41 143.3 9.3 3.8 2 2 0 2 2 2 1 Leishmanolysin EGF_Tenascin PF18720.1 EGR33997.1 - 1.9e-05 24.6 8.9 1.9e-05 24.6 8.9 4.2 4 0 0 4 4 4 1 Tenascin EGF domain Furin-like_2 PF15913.5 EGR33997.1 - 0.00016 21.8 14.3 0.00016 21.8 14.3 7.1 2 1 5 7 7 7 2 Furin-like repeat, cysteine-rich EGF_2 PF07974.13 EGR33997.1 - 0.008 16.5 11.8 0.008 16.5 11.8 7.8 6 2 0 6 6 6 1 EGF-like domain YabA PF06156.13 EGR33998.1 - 9.6 6.9 19.7 7 7.3 5.8 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Tfb2 PF03849.14 EGR33999.1 - 6.2e-40 137.3 21.9 1.2e-39 136.4 21.9 1.4 1 1 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.6 EGR33999.1 - 0.11 12.7 0.0 0.36 11.0 0.0 1.8 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Peptidase_C54 PF03416.19 EGR34000.1 - 1.2e-31 110.1 0.7 1.5e-31 109.8 0.7 1.1 1 0 0 1 1 1 1 Peptidase family C54 ICAT PF06384.11 EGR34001.1 - 0.077 13.3 1.4 0.17 12.1 1.4 1.6 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT Atg8 PF02991.16 EGR34001.1 - 0.2 11.9 5.1 0.13 12.5 2.9 1.6 1 1 1 2 2 2 0 Autophagy protein Atg8 ubiquitin like MFS_1 PF07690.16 EGR34002.1 - 1.2e-07 31.0 5.0 1.6e-07 30.6 5.0 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGR34002.1 - 4e-05 22.7 2.6 4e-05 22.7 2.6 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter UPF0506 PF11703.8 EGR34003.1 - 0.2 12.0 6.2 0.19 12.1 0.9 2.3 2 0 0 2 2 2 0 UPF0506 Pkinase PF00069.25 EGR34004.1 - 1.7e-74 250.5 0.7 2.5e-74 250.0 0.7 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34004.1 - 2.4e-45 154.8 0.0 3.3e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR34004.1 - 1.8e-09 37.3 0.0 3.3e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGR34004.1 - 1e-06 28.5 0.7 2.4e-06 27.3 0.7 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EGR34004.1 - 0.00022 21.3 0.0 0.00032 20.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR34004.1 - 0.00027 20.4 0.3 0.00045 19.6 0.3 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGR34004.1 - 0.00039 19.5 2.2 0.00079 18.5 2.2 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Choline_kinase PF01633.20 EGR34004.1 - 0.019 14.6 0.7 0.055 13.1 0.6 1.8 1 1 0 1 1 1 0 Choline/ethanolamine kinase IF2_N PF04760.15 EGR34004.1 - 0.032 14.0 0.2 0.097 12.5 0.2 1.8 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region FTA2 PF13095.6 EGR34004.1 - 0.038 13.6 1.4 0.44 10.1 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF2341 PF10102.9 EGR34005.1 - 0.13 12.8 1.6 0.3 11.7 0.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2341) DUF155 PF02582.14 EGR34006.1 - 0.093 12.8 0.1 0.16 12.1 0.1 1.5 1 1 0 1 1 1 0 Uncharacterised ACR, YagE family COG1723 Thioredoxin_4 PF13462.6 EGR34007.1 - 4.8e-05 23.6 1.9 0.00018 21.7 1.9 2.1 1 1 0 1 1 1 1 Thioredoxin PA PF02225.22 EGR34007.1 - 0.0059 16.6 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 PA domain DUF2232 PF09991.9 EGR34007.1 - 0.018 14.2 0.1 0.018 14.2 0.1 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) CaKB PF03185.15 EGR34007.1 - 0.021 14.5 1.3 0.021 14.5 1.3 1.9 2 0 0 2 2 2 0 Calcium-activated potassium channel, beta subunit YvfG PF09628.10 EGR34007.1 - 0.034 14.5 0.6 3.2 8.2 0.0 2.7 2 0 0 2 2 2 0 YvfG protein PRIMA1 PF16101.5 EGR34007.1 - 0.071 13.2 0.3 0.071 13.2 0.3 2.0 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Pox_A3L PF05288.11 EGR34007.1 - 0.27 11.2 4.8 3.5 7.7 1.4 2.8 2 0 0 2 2 2 0 Poxvirus A3L Protein DUF2039 PF10217.9 EGR34012.1 - 4.1e-23 81.5 23.9 4.1e-23 81.5 23.9 2.4 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2039) zinc_ribbon_16 PF17034.5 EGR34012.1 - 0.01 16.0 8.5 0.02 15.1 8.5 1.5 1 0 0 1 1 1 0 Zinc-ribbon like family DUF223 PF02721.14 EGR34012.1 - 0.025 14.9 1.4 3.7 7.9 0.1 2.8 2 2 0 2 2 2 0 Domain of unknown function DUF223 FYVE PF01363.21 EGR34012.1 - 0.18 12.0 18.2 0.21 11.8 11.3 2.5 1 1 1 2 2 2 0 FYVE zinc finger zinc-ribbons_6 PF07191.12 EGR34012.1 - 2.9 7.9 18.9 7.6 6.6 17.5 2.3 1 1 1 2 2 2 0 zinc-ribbons Bax1-I PF01027.20 EGR34013.1 - 5.6e-14 52.5 3.1 6.2e-14 52.3 3.1 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 BofA PF07441.11 EGR34013.1 - 0.023 14.9 0.3 0.023 14.9 0.3 2.5 2 1 1 3 3 3 0 SigmaK-factor processing regulatory protein BofA TPR_19 PF14559.6 EGR34015.1 - 1.1e-10 41.8 10.2 3.3e-05 24.3 2.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR34015.1 - 7.5e-05 22.9 8.1 0.075 13.3 0.3 3.2 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_20 PF14561.6 EGR34015.1 - 0.00032 21.0 6.2 0.0072 16.6 0.4 3.3 2 1 2 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGR34015.1 - 0.00034 20.6 4.2 0.0052 16.8 0.2 2.8 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 EGR34015.1 - 0.016 15.2 1.5 5.5 7.2 0.1 4.7 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGR34015.1 - 0.019 15.3 12.6 0.031 14.6 0.3 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat Rapsyn_N PF10579.9 EGR34015.1 - 0.039 14.0 0.1 0.23 11.6 0.0 2.3 3 0 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region TPR_14 PF13428.6 EGR34015.1 - 0.16 12.9 0.6 8.5 7.5 0.3 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat E2F_CC-MB PF16421.5 EGR34015.1 - 2.2 8.7 7.4 21 5.5 6.3 2.6 1 1 0 1 1 1 0 E2F transcription factor CC-MB domain TPR_6 PF13174.6 EGR34015.1 - 5 8.0 5.5 55 4.7 0.0 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat LSM PF01423.22 EGR34016.1 - 0.0014 18.2 1.2 0.34 10.6 0.0 2.6 2 1 1 3 3 3 2 LSM domain DUF4028 PF13220.6 EGR34016.1 - 0.054 13.3 0.0 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4028) EF-hand_6 PF13405.6 EGR34017.1 - 2.2e-17 61.5 2.9 2.6e-08 33.1 0.0 4.9 4 1 1 5 5 5 2 EF-hand domain EF-hand_7 PF13499.6 EGR34017.1 - 9.7e-17 61.2 0.6 8.4e-08 32.6 0.1 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR34017.1 - 2.4e-16 58.0 8.1 1e-08 34.1 0.0 4.9 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 EGR34017.1 - 2.5e-12 46.4 2.6 0.001 18.9 0.0 4.3 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EGR34017.1 - 1.1e-08 34.1 4.9 7.5e-05 22.0 0.0 4.0 4 0 0 4 4 4 2 EF hand EF-hand_9 PF14658.6 EGR34017.1 - 1.8e-06 28.2 0.0 0.0025 18.1 0.0 2.9 2 1 0 2 2 2 2 EF-hand domain HTH_40 PF14493.6 EGR34017.1 - 0.0002 21.8 0.3 0.0035 17.8 0.0 2.3 1 1 1 2 2 2 1 Helix-turn-helix domain EF-hand_14 PF17959.1 EGR34017.1 - 0.003 17.9 0.6 1.4 9.3 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain TerB PF05099.13 EGR34017.1 - 0.051 13.5 0.1 2.5 8.1 0.0 2.7 1 1 1 2 2 2 0 Tellurite resistance protein TerB DUF3008 PF11450.8 EGR34017.1 - 0.057 13.6 0.1 0.16 12.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknwon function (DUF3008) ERAP1_C PF11838.8 EGR34017.1 - 0.088 12.3 0.0 0.21 11.1 0.0 1.7 1 1 0 1 1 1 0 ERAP1-like C-terminal domain NYD-SP28 PF14772.6 EGR34017.1 - 0.088 12.9 0.5 1.1 9.4 0.0 2.4 2 1 0 2 2 2 0 Sperm tail SUB1_ProdP9 PF18213.1 EGR34017.1 - 0.11 12.4 0.4 0.68 9.8 0.0 2.1 2 1 0 2 2 2 0 SUB1 protease Prodomain ProdP9 DUF4093 PF13331.6 EGR34017.1 - 0.11 12.9 0.2 0.82 10.1 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4093) Acetyltransf_11 PF13720.6 EGR34017.1 - 0.12 12.9 0.0 1.6 9.3 0.0 2.5 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 YolD PF08863.10 EGR34017.1 - 0.12 12.4 0.6 4.3 7.5 0.0 2.6 2 1 0 2 2 2 0 YolD-like protein ApbA_C PF08546.11 EGR34017.1 - 0.12 12.5 0.1 9.8 6.4 0.0 2.1 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal Peptidase_M18 PF02127.15 EGR34018.1 - 3.3e-55 187.6 0.1 3.9e-55 187.4 0.1 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) FliL PF03748.14 EGR34018.1 - 0.039 14.5 0.2 0.076 13.6 0.2 1.6 1 0 0 1 1 1 0 Flagellar basal body-associated protein FliL Peptidase_M18 PF02127.15 EGR34019.1 - 2.3e-43 148.6 0.0 2.6e-43 148.4 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EGR34019.1 - 3e-05 23.2 0.1 3.4e-05 23.0 0.1 1.0 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase Ion_trans PF00520.31 EGR34020.1 - 1.6e-16 60.3 33.1 1.6e-16 60.3 33.1 3.0 2 1 0 2 2 2 1 Ion transport protein cNMP_binding PF00027.29 EGR34020.1 - 2.3e-14 53.2 0.0 4e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGR34020.1 - 4e-11 42.7 3.7 4e-11 42.7 3.7 2.5 2 0 0 2 2 2 1 Ion channel Peptidase_C1 PF00112.23 EGR34021.1 - 1.3e-99 332.7 32.9 2.1e-50 171.8 10.7 2.2 2 0 0 2 2 2 2 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGR34021.1 - 6.8e-05 21.8 7.4 0.038 12.8 0.8 2.8 3 0 0 3 3 3 2 Peptidase C1-like family PTPRCAP PF15713.5 EGR34021.1 - 0.066 13.5 0.4 0.12 12.7 0.4 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF3172 PF11371.8 EGR34022.1 - 0.00056 19.6 1.5 0.00062 19.5 1.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3172) EAF PF09816.9 EGR34022.1 - 0.064 13.7 4.7 0.083 13.3 4.7 1.3 1 1 0 1 1 1 0 RNA polymerase II transcription elongation factor PCNA_C PF02747.15 EGR34023.1 - 2.9e-51 172.9 0.2 1.6e-47 160.9 0.0 2.2 2 0 0 2 2 2 2 Proliferating cell nuclear antigen, C-terminal domain PCNA_N PF00705.18 EGR34023.1 - 7.8e-46 154.9 0.6 1.4e-45 154.1 0.6 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain Rad1 PF02144.16 EGR34023.1 - 1.5e-07 30.7 2.2 2.4e-05 23.6 2.2 2.2 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 EGR34023.1 - 6e-07 29.2 0.4 7.8e-07 28.8 0.4 1.2 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 EGR34023.1 - 0.055 12.6 0.2 0.28 10.3 0.0 2.0 2 1 0 2 2 2 0 Hus1-like protein FtsJ PF01728.19 EGR34025.1 - 3.3e-16 59.9 0.0 3.9e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pkinase PF00069.25 EGR34026.1 - 1.9e-64 217.6 1.2 2.9e-64 217.0 1.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34026.1 - 9.6e-34 116.8 0.2 1.4e-33 116.3 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR34026.1 - 8.2e-06 25.9 0.0 0.0047 16.9 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGR34026.1 - 0.00024 20.0 0.0 0.00044 19.1 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR34026.1 - 0.00057 19.3 0.1 0.0011 18.4 0.1 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGR34026.1 - 0.008 15.5 0.1 0.02 14.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like NCD3G PF07562.14 EGR34027.1 - 9.2e-06 25.5 14.9 0.021 14.8 1.1 3.4 3 0 0 3 3 3 3 Nine Cysteines Domain of family 3 GPCR Ephrin_rec_like PF07699.13 EGR34027.1 - 0.004 16.9 1.9 0.004 16.9 1.9 4.8 3 1 2 5 5 5 4 Putative ephrin-receptor like TNFR_c6 PF00020.18 EGR34027.1 - 0.34 11.3 14.7 1.3 9.5 0.2 4.2 3 1 1 4 4 4 0 TNFR/NGFR cysteine-rich region Laminin_EGF PF00053.24 EGR34027.1 - 0.45 10.7 17.1 14 5.9 2.1 4.6 2 1 2 4 4 4 0 Laminin EGF domain Fer4_10 PF13237.6 EGR34027.1 - 6 7.1 17.3 3.8 7.7 5.4 3.4 2 2 1 3 3 3 0 4Fe-4S dicluster domain SOUL PF04832.12 EGR34028.1 - 6.2e-41 140.4 2.7 5.5e-40 137.3 2.7 1.9 1 1 0 1 1 1 1 SOUL heme-binding protein zf-CCCH PF00642.24 EGR34030.1 - 4.9e-06 26.3 1.0 8.2e-06 25.6 1.0 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Phage_antitermQ PF06530.12 EGR34030.1 - 0.0076 16.2 0.1 0.011 15.6 0.1 1.2 1 0 0 1 1 1 1 Phage antitermination protein Q DUF1523 PF07509.11 EGR34030.1 - 0.022 14.1 0.0 0.022 14.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1523) zf_CCCH_4 PF18345.1 EGR34030.1 - 0.37 10.9 2.5 0.7 10.0 2.5 1.5 1 0 0 1 1 1 0 Zinc finger domain Guanylate_cyc PF00211.20 EGR34031.1 - 6.3e-17 61.8 0.0 1.3e-16 60.8 0.0 1.4 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain WD40 PF00400.32 EGR34032.1 - 0.029 15.2 0.1 0.13 13.1 0.1 2.0 2 0 0 2 2 2 0 WD domain, G-beta repeat PDEase_I PF00233.19 EGR34033.1 - 8.5e-67 225.3 8.1 8.5e-67 225.3 8.1 1.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Imm57 PF15596.6 EGR34033.1 - 0.079 13.3 0.2 0.23 11.8 0.0 1.9 2 0 0 2 2 2 0 Immunity protein 57 HD PF01966.22 EGR34033.1 - 0.11 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 HD domain SHS2_FTSA PF02491.20 EGR34033.1 - 0.28 11.6 3.3 0.59 10.6 0.6 2.9 3 0 0 3 3 3 0 SHS2 domain inserted in FTSA Actin PF00022.19 EGR34034.1 - 9.8e-87 291.2 0.2 1.2e-86 290.9 0.2 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGR34034.1 - 0.097 11.5 0.0 0.26 10.1 0.1 1.6 2 0 0 2 2 2 0 MreB/Mbl protein BAH PF01426.18 EGR34034.1 - 0.11 12.4 0.4 0.24 11.2 0.4 1.7 1 0 0 1 1 1 0 BAH domain SAM_Exu PF18609.1 EGR34034.1 - 0.91 9.7 3.0 1.1 9.4 0.1 2.5 3 0 0 3 3 3 0 Exuperantia SAM-like domain Carb_kinase PF01256.17 EGR34035.1 - 3.6e-26 92.1 0.0 4e-21 75.6 0.0 2.1 1 1 1 2 2 2 2 Carbohydrate kinase PDEase_I PF00233.19 EGR34036.1 - 2.7e-85 285.9 3.3 6.4e-85 284.7 3.3 1.7 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ion_trans PF00520.31 EGR34036.1 - 5.1e-05 22.6 6.9 5.1e-05 22.6 6.9 1.6 1 1 0 1 1 1 1 Ion transport protein EF-hand_1 PF00036.32 EGR34037.1 - 9e-14 49.9 2.8 7.1e-06 25.2 0.4 2.3 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGR34037.1 - 7.2e-13 47.4 4.8 7.6e-07 28.4 0.2 2.3 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGR34037.1 - 3.7e-12 45.1 1.2 5.4e-05 22.8 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EGR34037.1 - 7.7e-10 39.1 7.5 6.9e-08 32.8 2.1 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGR34037.1 - 1.4e-06 28.1 1.8 0.032 14.1 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGR34037.1 - 0.0027 18.0 2.9 0.87 9.9 0.1 2.3 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EGR34037.1 - 0.0083 16.4 0.1 2.2 8.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain DctM PF06808.12 EGR34038.1 - 0.26 10.1 8.7 0.029 13.2 3.8 1.7 1 1 0 1 1 1 0 Tripartite ATP-independent periplasmic transporter, DctM component TMEM132D_C PF15706.5 EGR34041.1 - 8.9 6.2 6.3 2.6 7.9 0.3 2.2 1 1 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term SF-assemblin PF06705.11 EGR34042.1 - 3.4e-12 46.3 35.2 4e-12 46.0 35.2 1.0 1 0 0 1 1 1 1 SF-assemblin/beta giardin PEP-utilisers_N PF05524.13 EGR34042.1 - 0.054 13.7 0.5 0.054 13.7 0.5 2.3 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal DUF4717 PF15838.5 EGR34042.1 - 0.14 12.2 4.5 0.14 12.2 1.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4717) PTPS_related PF10131.9 EGR34042.1 - 0.15 10.4 1.7 0.17 10.2 1.7 1.1 1 0 0 1 1 1 0 6-pyruvoyl-tetrahydropterin synthase related domain; membrane protein DUF883 PF05957.13 EGR34042.1 - 1.9 9.1 8.7 8.5 7.1 3.9 2.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) FAD-SLDH PF12318.8 EGR34042.1 - 2.9 7.9 3.9 2.2 8.3 0.2 2.3 1 1 2 3 3 3 0 Membrane bound FAD containing D-sorbitol dehydrogenase DUF4411 PF14367.6 EGR34042.1 - 4.8 7.1 9.8 1.5 8.7 2.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4411) GLTP PF08718.11 EGR34042.1 - 6.2 7.1 10.6 3.3e+02 1.5 10.3 2.8 1 1 0 1 1 1 0 Glycolipid transfer protein (GLTP) LptF_LptG PF03739.14 EGR34042.1 - 6.6 5.5 8.0 8.2 5.2 8.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Baculo_PEP_C PF04513.12 EGR34042.1 - 7.1 6.7 10.2 7.1 6.7 0.4 3.1 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Virulence_fact PF13769.6 EGR34042.1 - 7.1 6.9 9.3 5.5 7.3 2.7 3.5 1 1 2 3 3 3 0 Virulence factor Baculo_p24 PF05073.12 EGR34042.1 - 7.5 6.3 17.8 0.87 9.3 3.3 3.1 1 1 2 3 3 3 0 Baculovirus P24 capsid protein DUF948 PF06103.11 EGR34042.1 - 7.7 6.9 6.4 41 4.5 3.0 3.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HAP2-GCS1 PF10699.9 EGR34043.1 - 4.2e-20 71.4 0.2 1.1e-19 70.1 0.2 1.8 1 0 0 1 1 1 1 Male gamete fusion factor Invasin_D3 PF09134.10 EGR34043.1 - 0.061 13.6 0.4 0.14 12.5 0.4 1.5 1 0 0 1 1 1 0 Invasin, domain 3 Deltameth_res PF16020.5 EGR34043.1 - 0.1 12.5 0.0 0.28 11.1 0.0 1.7 1 0 0 1 1 1 0 Deltamethrin resistance Vps16_N PF04841.13 EGR34044.1 - 2.6e-34 118.7 3.4 2.6e-34 118.7 3.4 2.7 2 1 0 2 2 2 1 Vps16, N-terminal region Vps16_C PF04840.12 EGR34044.1 - 1.3e-11 44.1 41.5 6.7e-11 41.8 29.9 2.9 2 1 1 3 3 3 2 Vps16, C-terminal region TPR_8 PF13181.6 EGR34044.1 - 0.84 10.0 7.3 0.11 12.8 1.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGR34044.1 - 0.97 9.4 8.3 0.48 10.3 1.3 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGR34044.1 - 1 9.7 4.5 0.72 10.1 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat Peptidase_M16 PF00675.20 EGR34045.1 - 1.7e-33 115.7 0.1 5.3e-33 114.1 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGR34045.1 - 0.00074 19.6 0.7 0.0095 16.0 0.1 2.2 2 0 0 2 2 2 1 Peptidase M16 inactive domain DUF3169 PF11368.8 EGR34045.1 - 0.007 15.9 1.0 0.012 15.1 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3169) HEAT PF02985.22 EGR34046.1 - 3.2e-40 132.7 7.0 0.0088 16.2 0.0 14.2 15 0 0 15 15 15 10 HEAT repeat HEAT_2 PF13646.6 EGR34046.1 - 7.5e-28 96.8 0.0 9.2e-05 22.8 0.0 8.1 2 1 7 9 9 9 8 HEAT repeats Vac14_Fab1_bd PF12755.7 EGR34046.1 - 1.9e-11 44.4 15.9 0.3 11.7 0.7 8.0 3 3 7 10 10 10 6 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGR34046.1 - 2.5e-09 37.4 24.4 0.00012 22.2 0.8 5.5 2 1 3 6 6 6 4 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EGR34046.1 - 5.1e-08 33.3 0.9 0.41 11.2 0.0 6.8 9 0 0 9 9 9 1 HEAT-like repeat NUC173 PF08161.12 EGR34046.1 - 0.018 14.7 0.6 0.22 11.1 0.0 3.0 2 1 1 3 3 3 0 NUC173 domain RTP1_C1 PF10363.9 EGR34046.1 - 0.019 15.1 9.1 15 5.8 0.5 5.7 4 3 1 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 DUF61 PF01886.16 EGR34046.1 - 0.024 14.7 8.4 0.16 12.0 0.5 3.7 3 1 1 4 4 4 0 Protein of unknown function DUF61 Tti2 PF10521.9 EGR34046.1 - 0.049 13.2 3.4 0.38 10.2 0.0 3.5 3 1 1 4 4 4 0 Tti2 family Pro_isomerase PF00160.21 EGR34047.1 - 4.1e-46 157.1 0.0 8.3e-46 156.1 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SYF2 PF08231.12 EGR34047.1 - 1.2e-13 51.8 17.8 1.2e-13 51.8 17.8 3.1 1 1 1 2 2 2 1 SYF2 splicing factor LsmAD PF06741.13 EGR34047.1 - 0.019 15.5 3.4 0.019 15.5 3.4 2.7 2 1 0 2 2 2 0 LsmAD domain KxDL PF10241.9 EGR34047.1 - 8.1 6.8 9.7 2.8 8.3 2.3 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein Ras PF00071.22 EGR34048.1 - 4.5e-11 42.6 0.0 9.7e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR34048.1 - 9.5e-11 42.0 0.1 2.5e-10 40.6 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Methyltransf_2 PF00891.18 EGR34049.1 - 0.091 12.0 0.5 2 7.7 0.1 2.9 1 1 1 2 2 2 0 O-methyltransferase domain Invasin_D3 PF09134.10 EGR34049.1 - 3.1 8.2 23.0 9 6.7 1.9 6.9 2 2 4 8 8 8 0 Invasin, domain 3 TPR_2 PF07719.17 EGR34050.1 - 4.8e-24 82.5 29.1 7.9e-06 25.6 1.5 8.4 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_1 PF00515.28 EGR34050.1 - 7.1e-23 79.4 34.7 1.5e-05 24.6 2.3 8.5 8 1 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 EGR34050.1 - 3.8e-17 62.3 16.3 2.3e-05 24.6 0.6 5.0 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGR34050.1 - 6.8e-16 57.1 21.6 0.00081 19.4 0.0 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 EGR34050.1 - 3.6e-13 49.8 10.8 0.0029 18.1 0.0 5.7 2 2 4 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGR34050.1 - 1.2e-11 45.1 3.0 1.4e-06 28.9 0.2 3.9 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGR34050.1 - 2.3e-10 40.1 18.9 0.0032 17.7 0.1 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGR34050.1 - 3.5e-10 39.4 21.7 0.028 14.1 0.3 7.2 5 2 2 7 7 7 4 TPR repeat TPR_14 PF13428.6 EGR34050.1 - 2.9e-09 37.0 2.7 0.093 13.6 0.0 6.1 5 2 2 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGR34050.1 - 7.6e-08 32.5 28.8 0.028 15.1 0.4 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGR34050.1 - 2.2e-07 30.4 5.3 0.26 11.4 0.0 5.8 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGR34050.1 - 0.005 16.9 0.0 9.1 6.5 0.0 3.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGR34050.1 - 0.0074 16.1 9.0 2.1 8.3 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat Spore_III_AB PF09548.10 EGR34050.1 - 0.018 15.2 3.7 0.066 13.3 3.7 2.0 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) APP_E2 PF12925.7 EGR34050.1 - 0.032 13.9 0.5 0.032 13.9 0.5 3.0 2 1 1 3 3 3 0 E2 domain of amyloid precursor protein DUF4810 PF16068.5 EGR34050.1 - 0.11 13.0 0.0 0.11 13.0 0.0 4.1 3 2 1 4 4 3 0 Domain of unknown function (DUF4810) ANAPC3 PF12895.7 EGR34050.1 - 0.2 11.9 23.6 0.35 11.1 3.9 4.8 2 2 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 CDP-OH_P_transf PF01066.21 EGR34051.1 - 5.3e-14 52.7 1.4 6.7e-14 52.4 0.2 1.8 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DNA_pol3_finger PF17657.1 EGR34051.1 - 0.47 9.8 3.8 3.8 6.8 0.0 2.2 2 0 0 2 2 2 0 Bacterial DNA polymerase III alpha subunit finger domain Pro_isomerase PF00160.21 EGR34052.1 - 1.6e-52 178.0 0.2 1.6e-52 178.0 0.2 2.3 2 1 1 3 3 3 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EGR34052.1 - 4e-05 24.3 0.6 0.91 10.5 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.8 EGR34052.1 - 0.011 14.5 0.3 0.34 9.5 0.0 2.7 3 0 0 3 3 3 0 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGR34052.1 - 0.015 15.6 0.3 0.4 11.0 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain SUKH_6 PF14568.6 EGR34052.1 - 1.2 9.6 10.4 3 8.3 0.1 3.6 4 1 0 4 4 4 0 SMI1-KNR4 cell-wall LRR_2 PF07723.13 EGR34053.1 - 1.6 9.5 5.2 11 6.9 0.1 2.7 3 0 0 3 3 3 0 Leucine Rich Repeat WD40 PF00400.32 EGR34054.1 - 6.8e-10 39.4 0.6 0.00045 21.0 0.0 3.5 3 1 0 3 3 3 3 WD domain, G-beta repeat Nup160 PF11715.8 EGR34054.1 - 6.5e-06 25.1 0.7 0.0026 16.5 0.0 2.0 1 1 0 2 2 2 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 EGR34054.1 - 0.038 12.9 0.7 1.7 7.5 0.1 2.2 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain ANAPC4_WD40 PF12894.7 EGR34054.1 - 0.042 14.2 1.0 1.2 9.5 0.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain HATPase_c PF02518.26 EGR34055.1 - 3.4e-17 63.0 0.2 6.7e-17 62.0 0.2 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGR34055.1 - 5.2e-17 62.0 0.1 8.8e-17 61.3 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c_3 PF13589.6 EGR34055.1 - 0.0015 18.4 0.2 0.0025 17.7 0.2 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGR34055.1 - 0.0025 17.8 0.0 0.007 16.4 0.0 1.8 1 1 0 1 1 1 1 His Kinase A (phospho-acceptor) domain GST_C_6 PF17171.4 EGR34055.1 - 0.095 12.5 0.2 1.4 8.7 0.1 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Palm_thioest PF02089.15 EGR34056.1 - 6e-66 222.7 0.1 9.8e-66 222.0 0.1 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Pkinase PF00069.25 EGR34056.1 - 1.5e-31 109.8 2.0 2.3e-31 109.2 2.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34056.1 - 8.3e-18 64.6 0.2 1.2e-17 64.1 0.2 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR34056.1 - 2.3e-09 36.6 0.1 3e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase SMI1_KNR4 PF09346.10 EGR34056.1 - 0.027 14.8 0.3 9.8 6.6 0.0 2.8 2 0 0 2 2 2 0 SMI1 / KNR4 family (SUKH-1) APH PF01636.23 EGR34056.1 - 0.037 14.0 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family BAAT_C PF08840.11 EGR34056.1 - 0.095 12.6 0.1 0.33 10.8 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PGAP1 PF07819.13 EGR34056.1 - 0.11 12.2 0.0 0.4 10.3 0.0 2.1 2 0 0 2 2 2 0 PGAP1-like protein GlcNAc-1_reg PF18440.1 EGR34056.1 - 0.18 12.1 1.5 48 4.3 0.2 3.5 3 0 0 3 3 3 0 Putative GlcNAc-1 phosphotransferase regulatory domain TK PF00265.18 EGR34057.1 - 1.4e-61 207.5 6.3 1.6e-61 207.3 6.3 1.0 1 0 0 1 1 1 1 Thymidine kinase ATPase_2 PF01637.18 EGR34057.1 - 0.00087 19.3 1.5 0.0011 18.9 1.5 1.3 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_14 PF13173.6 EGR34057.1 - 0.0031 17.6 2.5 0.0091 16.0 2.5 1.6 1 1 0 1 1 1 1 AAA domain Bac_DnaA PF00308.18 EGR34057.1 - 0.043 13.7 2.1 0.63 9.8 2.1 2.1 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_22 PF13401.6 EGR34057.1 - 0.043 14.1 0.0 0.065 13.5 0.0 1.2 1 0 0 1 1 1 0 AAA domain MCM_OB PF17207.3 EGR34057.1 - 0.2 11.5 5.5 0.5 10.2 0.3 2.2 2 0 0 2 2 2 0 MCM OB domain Prot_inhib_II PF02428.15 EGR34057.1 - 0.92 10.0 5.8 12 6.5 0.3 3.6 3 0 0 3 3 3 0 Potato type II proteinase inhibitor family Band_7 PF01145.25 EGR34058.1 - 1e-20 74.5 8.2 2.6e-20 73.2 1.3 2.0 1 1 1 2 2 2 2 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EGR34058.1 - 0.00086 18.5 2.3 0.0025 16.9 2.5 1.6 1 1 1 2 2 2 1 SigmaW regulon antibacterial Methyltransf_5 PF01795.19 EGR34058.1 - 0.015 14.8 2.2 0.024 14.1 2.2 1.2 1 0 0 1 1 1 0 MraW methylase family EzrA PF06160.12 EGR34059.1 - 9.6e-05 20.7 18.9 0.0012 17.1 3.7 2.4 1 1 1 2 2 2 2 Septation ring formation regulator, EzrA Sec34 PF04136.15 EGR34059.1 - 0.026 14.4 14.9 0.091 12.6 4.9 2.2 1 1 1 2 2 2 0 Sec34-like family TPD52 PF04201.15 EGR34059.1 - 0.072 12.7 1.0 0.12 12.0 0.9 1.7 1 1 0 1 1 1 0 Tumour protein D52 family Helicase_IV_N PF12462.8 EGR34059.1 - 0.11 12.5 2.9 0.22 11.5 2.9 1.5 1 0 0 1 1 1 0 DNA helicase IV / RNA helicase N terminal TACC_C PF05010.14 EGR34059.1 - 0.11 12.3 12.6 0.44 10.3 5.4 2.2 2 0 0 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF1664 PF07889.12 EGR34059.1 - 0.27 11.3 9.5 2.7 8.0 2.7 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) Arc_PepC_II PF06847.11 EGR34059.1 - 0.32 11.5 1.1 21 5.7 0.1 2.4 2 0 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II Interferon PF00143.19 EGR34059.1 - 0.77 9.9 10.9 0.15 12.2 6.0 1.9 1 1 1 2 2 2 0 Interferon alpha/beta domain Nsp1_C PF05064.13 EGR34059.1 - 0.84 9.5 17.3 1 9.2 7.8 3.5 1 1 1 2 2 2 0 Nsp1-like C-terminal region PI_PP_I PF18363.1 EGR34059.1 - 1.2 9.4 13.9 1.4 9.2 1.1 3.3 1 1 3 4 4 4 0 Phosphoinositide phosphatase insertion domain Phage_GPO PF05929.11 EGR34059.1 - 1.6 8.3 5.2 6 6.4 2.4 2.0 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase RecG_N PF17190.4 EGR34059.1 - 3.6 8.4 10.9 1.9 9.3 2.5 2.6 1 1 2 3 3 3 0 RecG N-terminal helical domain Muted PF14942.6 EGR34059.1 - 3.9 7.8 16.1 0.19 12.1 2.6 2.7 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Fib_alpha PF08702.10 EGR34059.1 - 4.7 7.4 21.3 0.93 9.7 8.2 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Fzo_mitofusin PF04799.13 EGR34059.1 - 5.2 6.6 10.8 1.4 8.4 0.8 2.7 1 1 1 3 3 3 0 fzo-like conserved region Mce4_CUP1 PF11887.8 EGR34059.1 - 7.2 6.0 6.6 3.9 6.8 1.3 2.2 2 1 0 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative Peptidase_M8 PF01457.16 EGR34061.1 - 9.5e-38 130.2 0.1 1.3e-37 129.7 0.1 1.0 1 0 0 1 1 1 1 Leishmanolysin BSP PF04450.12 EGR34061.1 - 0.0014 18.4 0.3 0.22 11.3 0.0 2.3 2 0 0 2 2 2 2 Peptidase of plants and bacteria NCBP3 PF10309.9 EGR34061.1 - 0.12 12.2 0.1 3.1 7.7 0.0 2.6 2 0 0 2 2 2 0 Nuclear cap-binding protein subunit 3 RIIa PF02197.17 EGR34061.1 - 0.19 11.4 0.1 14 5.4 0.0 2.9 3 0 0 3 3 3 0 Regulatory subunit of type II PKA R-subunit Peptidase_M8 PF01457.16 EGR34062.1 - 2.5e-10 39.7 3.9 1.9e-09 36.8 0.0 2.2 1 1 1 2 2 2 1 Leishmanolysin DUF5560 PF17715.1 EGR34062.1 - 0.02 14.3 0.1 0.027 13.9 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5560) Zincin_1 PF06262.11 EGR34062.1 - 0.15 12.2 0.1 0.27 11.4 0.1 1.3 1 0 0 1 1 1 0 Zincin-like metallopeptidase Asp PF00026.23 EGR34063.1 - 2e-55 188.4 7.8 2.5e-55 188.1 7.8 1.1 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGR34063.1 - 3.1e-08 34.1 1.9 0.00058 20.1 0.4 2.2 1 1 1 2 2 2 2 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGR34063.1 - 1.3e-05 25.8 0.0 0.0014 19.2 0.0 3.0 2 1 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.6 EGR34063.1 - 0.0036 17.8 0.0 0.079 13.5 0.0 2.5 2 1 0 2 2 2 1 gag-polyprotein putative aspartyl protease Mito_carr PF00153.27 EGR34064.1 - 4.5e-56 186.8 7.3 6.8e-22 77.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGR34064.1 - 0.0044 16.2 1.7 0.2 10.8 0.5 2.6 1 1 1 3 3 3 2 Gammaproteobacterial serine protease SMP_2 PF10144.9 EGR34064.1 - 0.016 14.8 0.4 0.2 11.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial virulence factor haemolysin DnaI_N PF07319.11 EGR34064.1 - 0.17 12.6 2.9 0.73 10.5 0.1 2.7 3 0 0 3 3 3 0 Primosomal protein DnaI N-terminus Ras PF00071.22 EGR34065.1 - 1.3e-30 106.1 0.8 2.2e-30 105.4 0.7 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGR34065.1 - 7.9e-07 29.3 0.5 1.7e-06 28.2 0.1 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 EGR34065.1 - 0.0029 17.1 0.4 0.0065 16.0 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B LuxT_C PF18285.1 EGR34065.1 - 0.018 15.6 0.1 0.038 14.5 0.1 1.5 1 0 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain PH_6 PF15406.6 EGR34065.1 - 0.068 13.5 0.0 0.12 12.6 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Ala_racemase_N PF01168.20 EGR34066.1 - 2.2e-22 79.8 0.0 2.7e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain zf-RING_2 PF13639.6 EGR34067.1 - 7.2e-06 26.3 8.5 7.2e-06 26.3 8.5 8.4 8 3 1 9 9 9 1 Ring finger domain zf-RING_5 PF14634.6 EGR34067.1 - 0.00016 21.6 11.2 0.00016 21.6 11.2 7.9 6 3 1 7 7 7 2 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGR34067.1 - 0.0066 16.5 1.5 0.0066 16.5 1.5 6.0 7 0 0 7 7 7 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGR34067.1 - 0.013 15.3 0.4 0.013 15.3 0.4 8.0 10 0 0 10 10 10 0 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGR34067.1 - 0.021 14.6 5.2 0.021 14.6 5.2 5.0 5 0 0 5 5 5 0 RING-like zinc finger CENP-R PF06729.12 EGR34067.1 - 0.51 10.3 3.3 7.7 6.5 0.3 2.6 2 0 0 2 2 2 0 Kinetochore component, CENP-R Peptidase_M14 PF00246.24 EGR34068.1 - 1.3e-14 54.7 3.1 7.3e-14 52.2 3.0 2.4 1 1 0 1 1 1 1 Zinc carboxypeptidase Pepdidase_M14_N PF18027.1 EGR34068.1 - 1.8e-13 50.7 1.1 1.8e-13 50.7 1.1 2.5 3 0 0 3 3 3 1 Cytosolic carboxypeptidase N-terminal domain DUF2457 PF10446.9 EGR34068.1 - 0.073 12.2 9.7 0.1 11.7 9.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) PAS PF00989.25 EGR34069.1 - 0.0014 18.6 0.0 0.03 14.3 0.0 2.9 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EGR34069.1 - 0.15 12.3 0.0 0.15 12.3 0.0 4.6 5 1 0 5 5 5 0 PAS domain TMEM154 PF15102.6 EGR34070.1 - 0.077 12.9 0.7 0.12 12.2 0.7 1.4 1 0 0 1 1 1 0 TMEM154 protein family Thioredoxin_16 PF18569.1 EGR34070.1 - 3.7 7.7 6.9 0.28 11.3 0.3 2.4 3 0 0 3 3 3 0 Thioredoxin-like domain Methyltransf_23 PF13489.6 EGR34071.1 - 0.1 12.4 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain TPR_1 PF00515.28 EGR34072.1 - 1.2e-19 69.2 18.0 7.3e-10 38.2 0.4 5.3 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGR34072.1 - 3.6e-16 57.9 11.2 2.6e-06 27.1 0.1 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGR34072.1 - 1.2e-09 37.6 23.6 0.00014 21.8 0.4 6.6 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGR34072.1 - 5e-09 35.7 8.9 0.00013 21.6 0.6 3.9 3 1 1 4 4 4 2 TPR repeat TPR_17 PF13431.6 EGR34072.1 - 1.7e-08 34.3 4.7 0.00026 21.1 0.4 4.3 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGR34072.1 - 1.7e-07 31.6 0.8 0.00089 19.7 0.1 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGR34072.1 - 2.7e-07 30.8 1.1 0.019 15.2 0.2 3.9 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGR34072.1 - 0.00019 22.0 0.0 0.00054 20.6 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGR34072.1 - 0.00024 21.2 0.0 0.017 15.3 0.0 2.6 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGR34072.1 - 0.0013 19.4 0.0 3 8.9 0.0 4.0 2 1 2 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGR34072.1 - 0.0013 18.6 0.3 0.24 11.5 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR34072.1 - 0.0015 18.7 6.4 0.014 15.6 4.5 3.0 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.18 EGR34072.1 - 0.0081 16.2 5.1 0.095 12.8 2.8 3.7 2 1 1 3 3 3 1 MIT (microtubule interacting and transport) domain DUF4382 PF14321.6 EGR34072.1 - 0.016 15.4 3.4 0.019 15.2 1.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4382) TPR_6 PF13174.6 EGR34072.1 - 0.034 14.8 3.1 35 5.3 0.0 4.9 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGR34072.1 - 0.051 13.5 0.0 4.3 7.4 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Pex26 PF07163.12 EGR34072.1 - 0.55 9.5 7.6 0.022 14.1 1.5 1.7 2 0 0 2 2 2 0 Pex26 protein Fis1_TPR_C PF14853.6 EGR34072.1 - 0.64 10.1 11.5 1.5 9.0 0.3 4.7 6 0 0 6 6 6 0 Fis1 C-terminal tetratricopeptide repeat Myb_DNA-binding PF00249.31 EGR34073.1 - 5.6e-08 32.8 0.2 8e-08 32.4 0.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGR34073.1 - 3e-05 24.2 0.2 4e-05 23.8 0.2 1.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain Imm47 PF15573.6 EGR34073.1 - 0.042 13.4 1.1 0.076 12.5 0.2 1.6 1 1 1 2 2 2 0 Immunity protein 47 Endonuc-dimeris PF09124.10 EGR34074.1 - 0.094 12.9 4.9 4.6 7.5 0.2 2.6 2 0 0 2 2 2 0 T4 recombination endonuclease VII, dimerisation SWIRM PF04433.17 EGR34074.1 - 4.3 7.7 9.6 2.9 8.3 3.8 2.6 1 1 0 2 2 2 0 SWIRM domain Ribosomal_L5_C PF00673.21 EGR34075.1 - 2.5e-21 75.7 0.1 4.3e-21 74.9 0.1 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.19 EGR34075.1 - 2.2e-19 69.5 0.0 3.7e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L5 HTH_ABP1_N PF18107.1 EGR34075.1 - 0.0024 17.5 0.3 0.0066 16.1 0.3 1.7 1 0 0 1 1 1 1 Fission yeast centromere protein N-terminal domain MORN PF02493.20 EGR34076.1 - 0.00022 21.0 0.3 0.00022 21.0 0.3 2.7 3 0 0 3 3 3 1 MORN repeat Kinesin PF00225.23 EGR34078.1 - 1.2e-24 86.9 2.8 1.4e-24 86.7 2.8 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR34078.1 - 1e-22 80.7 6.6 1e-22 80.7 6.6 1.3 1 1 0 1 1 1 1 Microtubule binding Pkinase PF00069.25 EGR34079.1 - 6.6e-32 110.9 0.0 6.8e-32 110.9 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34079.1 - 2.5e-18 66.3 0.0 2.7e-18 66.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR34079.1 - 0.0059 16.6 0.0 0.009 16.0 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGR34079.1 - 0.0094 14.8 0.0 0.0097 14.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Pkinase PF00069.25 EGR34080.1 - 1.7e-75 253.8 0.1 2.2e-75 253.4 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34080.1 - 2.1e-37 128.8 0.0 4.7e-37 127.7 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR34080.1 - 2.2e-08 33.5 0.2 5.9e-08 32.1 0.2 1.6 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGR34080.1 - 5.4e-08 32.5 0.0 3.2e-06 26.7 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGR34080.1 - 0.00068 19.0 0.0 0.0012 18.2 0.0 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR34080.1 - 0.003 17.5 0.0 0.0042 17.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGR34080.1 - 0.0041 16.2 0.1 0.0091 15.1 0.0 1.6 1 1 0 1 1 1 1 Seadornavirus VP7 RIO1 PF01163.22 EGR34080.1 - 0.0074 15.9 0.4 0.02 14.5 0.4 1.6 1 1 0 1 1 1 1 RIO1 family FTA2 PF13095.6 EGR34080.1 - 0.062 12.9 1.2 1.6 8.3 0.1 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF3449 PF11931.8 EGR34081.1 - 8e-71 237.6 4.4 8e-71 237.6 4.4 4.6 3 1 1 4 4 4 1 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.8 EGR34081.1 - 1.2e-09 37.9 0.5 5.3e-09 35.8 0.5 2.2 1 0 0 1 1 1 1 Splicing factor SF3a60 binding domain zf-C2H2_jaz PF12171.8 EGR34081.1 - 4.2e-05 23.7 2.9 4.2e-05 23.7 2.9 2.7 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding SF3A3 PF16837.5 EGR34081.1 - 4.6e-05 23.9 1.0 4.6e-05 23.9 1.0 6.7 6 3 0 6 6 6 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 zf-met PF12874.7 EGR34081.1 - 0.00051 20.3 9.6 0.0019 18.5 1.6 3.0 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-U1 PF06220.12 EGR34081.1 - 0.0074 16.0 0.8 0.022 14.5 0.3 2.0 2 0 0 2 2 2 1 U1 zinc finger OrsD PF12013.8 EGR34081.1 - 0.061 13.8 2.3 0.92 10.0 0.3 3.3 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Secretin_N_2 PF07655.13 EGR34081.1 - 0.6 10.7 11.1 2.2 8.9 11.1 2.0 1 0 0 1 1 1 0 Secretin N-terminal domain EBV-NA3 PF05009.12 EGR34081.1 - 0.9 9.0 7.0 2.1 7.8 0.2 2.5 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) zf-C2H2_4 PF13894.6 EGR34081.1 - 2.6 9.1 3.7 41 5.4 0.2 2.8 2 0 0 2 2 2 0 C2H2-type zinc finger Pkinase PF00069.25 EGR34082.1 - 5.5e-12 45.6 0.0 5.5e-12 45.6 0.0 2.9 2 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34082.1 - 4.8e-07 29.3 1.0 9.2e-07 28.4 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Peptidase_C33 PF05412.12 EGR34082.1 - 0.029 14.4 0.3 0.029 14.4 0.3 2.4 2 0 0 2 2 2 0 Equine arterivirus Nsp2-type cysteine proteinase TAXi_N PF14543.6 EGR34083.1 - 2.6e-20 73.4 2.2 2.6e-20 73.4 2.2 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp PF00026.23 EGR34083.1 - 5.1e-16 59.0 7.0 1.1e-10 41.4 2.2 3.8 2 1 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGR34083.1 - 0.0061 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal SARAF PF06682.12 EGR34083.1 - 0.012 15.3 0.7 0.012 15.3 0.7 2.1 3 0 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis Cortex-I_coil PF09304.10 EGR34083.1 - 0.25 11.6 2.9 0.54 10.5 2.9 1.4 1 0 0 1 1 1 0 Cortexillin I, coiled coil DHHC PF01529.20 EGR34083.1 - 4.8 7.3 14.1 0.45 10.6 1.1 3.0 3 0 0 3 3 3 0 DHHC palmitoyltransferase TNFR_16_TM PF18422.1 EGR34083.1 - 5.7 7.0 16.1 0.043 13.8 5.8 2.7 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain zf-CHY PF05495.12 EGR34083.1 - 9.7 6.8 11.0 10 6.7 5.8 3.1 3 0 0 3 3 3 0 CHY zinc finger MORN PF02493.20 EGR34084.1 - 1.1e-51 169.7 99.7 2.7e-05 23.8 1.0 13.3 13 0 0 13 13 13 13 MORN repeat DUF3048_C PF17479.2 EGR34084.1 - 0.0048 17.3 20.3 0.026 14.9 6.6 4.4 1 1 2 4 4 4 2 Protein of unknown function (DUF3048) C-terminal domain Transglut_i_TM PF14400.6 EGR34084.1 - 4.1 7.4 4.8 26 4.9 0.3 2.7 1 1 1 3 3 3 0 Inactive transglutaminase fused to 7 transmembrane helices UQ_con PF00179.26 EGR34085.1 - 1.4e-15 57.1 0.3 4e-15 55.7 0.3 1.8 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-NF-X1 PF01422.17 EGR34085.1 - 9.6e-10 38.3 152.8 1.7e-05 24.7 15.6 11.1 9 1 0 9 9 9 5 NF-X1 type zinc finger RWD PF05773.22 EGR34085.1 - 0.0048 17.2 0.9 0.014 15.7 0.0 2.3 2 0 0 2 2 2 1 RWD domain DUF4537 PF15057.6 EGR34085.1 - 0.016 15.2 1.2 0.14 12.2 0.1 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4537) Tudor_3 PF18115.1 EGR34085.1 - 1.9 8.4 4.1 2.6 8.0 0.0 2.8 3 0 0 3 3 3 0 DNA repair protein Crb2 Tudor domain Siah-Interact_N PF09032.11 EGR34086.1 - 7.1e-06 26.3 8.2 1.4e-05 25.3 8.2 1.8 1 1 0 1 1 1 1 Siah interacting protein, N terminal SGS PF05002.15 EGR34086.1 - 5.5e-05 23.2 2.6 8.5e-05 22.6 2.6 1.4 1 0 0 1 1 1 1 SGS domain Ribosomal_L38e PF01781.18 EGR34086.1 - 0.017 15.2 0.1 0.028 14.5 0.1 1.4 1 0 0 1 1 1 0 Ribosomal L38e protein family DUF3243 PF11588.8 EGR34086.1 - 0.019 15.2 1.2 0.047 14.0 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3243) SCAB-ABD PF16711.5 EGR34086.1 - 0.024 14.5 0.1 0.049 13.5 0.1 1.5 1 0 0 1 1 1 0 Actin-binding domain of plant-specific actin-binding protein Ca_chan_IQ PF08763.11 EGR34086.1 - 0.14 12.4 0.4 0.14 12.4 0.4 2.0 2 1 0 2 2 2 0 Voltage gated calcium channel IQ domain LCIB_C_CA PF18599.1 EGR34086.1 - 0.25 10.6 1.6 2.3 7.4 0.2 1.9 1 1 1 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Sec23_helical PF04815.15 EGR34087.1 - 3e-14 52.7 0.5 1e-13 51.0 0.5 1.9 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_trunk PF04811.15 EGR34087.1 - 1.2e-13 51.2 0.0 1.2e-13 51.2 0.0 2.1 2 0 0 2 2 2 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EGR34087.1 - 1.5e-12 48.0 0.4 7.7e-12 45.8 0.0 2.4 2 1 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gelsolin PF00626.22 EGR34087.1 - 0.00015 21.6 0.1 0.00036 20.4 0.1 1.8 1 0 0 1 1 1 1 Gelsolin repeat DUF4841 PF16129.5 EGR34087.1 - 0.1 12.9 0.2 0.3 11.3 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4841) Metallophos PF00149.28 EGR34088.1 - 6e-33 115.1 0.3 9.8e-33 114.4 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGR34088.1 - 0.0062 17.0 0.6 0.013 15.9 0.6 1.5 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Glyco_transf_36 PF06165.11 EGR34088.1 - 0.14 11.6 0.0 0.23 10.8 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase family 36 TniB PF05621.11 EGR34090.1 - 4.1e-05 23.1 0.8 0.0024 17.3 0.3 2.3 2 0 0 2 2 2 1 Bacterial TniB protein RsgA_GTPase PF03193.16 EGR34090.1 - 5.6e-05 23.1 3.6 0.028 14.3 0.1 2.4 2 1 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EGR34090.1 - 7.4e-05 23.0 0.1 0.00078 19.7 0.0 2.3 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 EGR34090.1 - 0.00064 19.7 0.0 0.058 13.3 0.0 2.3 1 1 1 2 2 2 1 NACHT domain AAA_16 PF13191.6 EGR34090.1 - 0.00079 19.8 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_7 PF12775.7 EGR34090.1 - 0.0019 17.7 0.0 0.0044 16.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing dynein motor region T2SSE PF00437.20 EGR34090.1 - 0.0019 17.3 0.1 0.0037 16.4 0.1 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein DUF815 PF05673.13 EGR34090.1 - 0.0025 17.0 0.0 0.0062 15.7 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF815) DUF87 PF01935.17 EGR34090.1 - 0.0049 17.0 6.9 0.012 15.7 6.9 1.7 1 1 0 1 1 1 1 Helicase HerA, central domain ABC_tran PF00005.27 EGR34090.1 - 0.0079 16.7 8.8 0.037 14.5 8.8 2.2 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGR34090.1 - 0.01 15.7 1.7 0.017 15.0 1.6 1.7 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Sigma54_activat PF00158.26 EGR34090.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain SMC_N PF02463.19 EGR34090.1 - 0.012 15.1 0.6 0.012 15.1 0.6 1.8 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain IstB_IS21 PF01695.17 EGR34090.1 - 0.014 15.2 0.0 0.037 13.8 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein RNA_helicase PF00910.22 EGR34090.1 - 0.015 15.7 1.0 0.015 15.7 1.0 2.6 3 1 0 3 3 2 0 RNA helicase MMR_HSR1 PF01926.23 EGR34090.1 - 0.016 15.3 1.6 0.057 13.5 1.6 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AFG1_ATPase PF03969.16 EGR34090.1 - 0.016 14.1 0.0 0.025 13.5 0.0 1.4 1 0 0 1 1 1 0 AFG1-like ATPase AAA_18 PF13238.6 EGR34090.1 - 0.019 15.5 1.0 0.045 14.3 0.2 2.0 1 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGR34090.1 - 0.028 14.2 0.0 0.056 13.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 EGR34090.1 - 0.029 14.8 0.0 0.18 12.2 0.0 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EGR34090.1 - 0.033 13.6 0.0 0.084 12.2 0.0 1.7 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI cobW PF02492.19 EGR34090.1 - 0.036 13.7 0.5 0.13 11.8 0.5 2.1 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 EGR34090.1 - 0.043 13.8 0.0 0.13 12.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) FtsK_SpoIIIE PF01580.18 EGR34090.1 - 0.049 13.0 0.0 0.14 11.4 0.0 1.7 2 0 0 2 2 2 0 FtsK/SpoIIIE family TsaE PF02367.17 EGR34090.1 - 0.055 13.5 0.0 0.18 11.8 0.0 2.0 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EGR34090.1 - 0.15 12.2 0.0 0.27 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Roc PF08477.13 EGR34090.1 - 0.32 11.2 5.5 0.25 11.6 0.3 3.1 2 2 2 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase EMP24_GP25L PF01105.24 EGR34091.1 - 6.2e-23 81.7 1.2 7.1e-23 81.5 1.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD MOZ_SAS PF01853.18 EGR34092.1 - 5.5e-75 251.0 0.9 4.3e-74 248.0 0.1 2.1 2 0 0 2 2 2 1 MOZ/SAS family zf-MYST PF17772.1 EGR34092.1 - 1.6e-21 75.7 5.5 1.6e-20 72.5 4.1 2.4 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 EGR34092.1 - 2.7e-09 36.8 2.1 2.7e-09 36.8 2.1 2.1 2 0 0 2 2 2 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EGR34092.1 - 0.007 16.8 0.0 0.022 15.2 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Chromo PF00385.24 EGR34092.1 - 0.19 11.6 3.3 0.64 10.0 0.9 2.5 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain Pkinase PF00069.25 EGR34093.1 - 2.2e-65 220.6 2.0 2.2e-65 220.6 2.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34093.1 - 1.1e-31 110.1 0.1 1.8e-31 109.3 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 EGR34093.1 - 1.9e-15 57.2 6.2 1.1e-08 35.5 0.9 3.5 4 1 1 5 5 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGR34093.1 - 7.2e-14 52.0 1.5 4.8e-07 30.2 0.3 3.7 3 1 2 5 5 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR34093.1 - 7.7e-13 47.4 2.6 0.00079 19.7 0.0 4.2 4 0 0 4 4 3 3 Ankyrin repeat Ank_5 PF13857.6 EGR34093.1 - 2.4e-12 46.8 1.9 2.5e-06 27.6 0.1 4.4 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EGR34093.1 - 7.4e-10 38.8 2.9 8.3e-05 22.9 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat APH PF01636.23 EGR34093.1 - 6.8e-05 22.9 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGR34093.1 - 0.00034 20.0 0.1 0.0039 16.6 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGR34093.1 - 0.012 15.0 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EGR34093.1 - 0.018 14.6 0.1 0.018 14.6 0.1 3.2 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL PH_8 PF15409.6 EGR34093.1 - 0.018 15.3 0.9 1.7 9.0 0.1 2.7 1 1 1 2 2 2 0 Pleckstrin homology domain DUF4268 PF14088.6 EGR34094.1 - 0.022 14.7 0.5 0.039 13.8 0.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4268) adh_short PF00106.25 EGR34095.1 - 8.6e-27 93.9 0.0 6.8e-25 87.7 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGR34095.1 - 4.1e-15 56.0 0.0 1e-13 51.4 0.0 2.0 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGR34095.1 - 8.1e-08 32.4 0.0 2.1e-07 31.0 0.0 1.7 2 1 0 2 2 2 1 KR domain Epimerase PF01370.21 EGR34095.1 - 0.0042 16.6 0.1 0.0065 16.0 0.0 1.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGR34095.1 - 0.015 14.7 0.2 0.041 13.3 0.0 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Homeodomain PF00046.29 EGR34095.1 - 0.08 12.8 0.3 0.2 11.5 0.3 1.7 1 0 0 1 1 1 0 Homeodomain Polysacc_synt_2 PF02719.15 EGR34095.1 - 0.13 11.3 0.1 0.22 10.7 0.0 1.4 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein MMR_HSR1_Xtn PF16897.5 EGR34096.1 - 3.9e-40 136.1 3.0 7.2e-40 135.3 3.0 1.4 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EGR34096.1 - 6.8e-21 74.1 0.0 1.5e-20 73.0 0.0 1.6 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EGR34096.1 - 2.6e-20 72.6 0.0 5e-20 71.7 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGR34096.1 - 5.5e-11 42.2 0.0 1.4e-10 40.9 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGR34096.1 - 0.0015 18.6 0.0 0.75 9.8 0.0 2.8 2 0 0 2 2 2 2 Dynamin family MeaB PF03308.16 EGR34096.1 - 0.0057 15.7 0.1 0.019 14.0 0.1 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 EGR34096.1 - 0.058 12.8 0.0 0.14 11.6 0.0 1.8 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit 2OG-FeII_Oxy_2 PF13532.6 EGR34097.1 - 0.0018 18.5 0.0 0.0018 18.5 0.0 3.0 3 0 0 3 3 3 1 2OG-Fe(II) oxygenase superfamily Csm1_N PF18504.1 EGR34099.1 - 2.1 8.8 21.1 0.038 14.3 4.7 3.6 3 2 1 4 4 4 0 Csm1 N-terminal domain Response_reg PF00072.24 EGR34100.1 - 0.001 19.2 0.0 0.0012 19.0 0.0 1.1 1 0 0 1 1 1 1 Response regulator receiver domain DUF4288 PF14119.6 EGR34100.1 - 0.068 13.6 0.3 0.11 13.0 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4288) EMC3_TMCO1 PF01956.16 EGR34101.1 - 0.017 14.8 0.9 0.023 14.5 0.9 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like zf-Mss51 PF13824.6 EGR34101.1 - 0.038 14.1 0.3 0.077 13.1 0.3 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 REJ PF02010.15 EGR34102.1 - 2.7e-10 39.7 6.2 5.5e-10 38.6 6.2 1.5 1 1 0 1 1 1 1 REJ domain Peptidase_M8 PF01457.16 EGR34103.1 - 0.031 13.0 0.0 0.035 12.8 0.0 1.1 1 0 0 1 1 1 0 Leishmanolysin Peptidase_M8 PF01457.16 EGR34104.1 - 1.9e-27 96.2 0.1 2.4e-27 95.9 0.1 1.1 1 0 0 1 1 1 1 Leishmanolysin FA_hydroxylase PF04116.13 EGR34105.1 - 4.1e-28 98.4 10.6 4.1e-28 98.4 10.6 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Toprim PF01751.22 EGR34106.1 - 0.5 10.6 6.3 1.6 9.0 1.2 2.6 1 1 1 2 2 2 0 Toprim domain ADK PF00406.22 EGR34108.1 - 1.9e-50 170.9 0.0 3.4e-50 170.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGR34108.1 - 2.8e-38 131.4 0.1 7.4e-38 130.1 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.6 EGR34108.1 - 1.2e-09 38.7 0.0 2.7e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF2475 PF10629.9 EGR34108.1 - 3.5e-07 30.3 5.1 4.4e-05 23.6 1.2 3.4 3 1 0 3 3 3 2 Protein of unknown function (DUF2475) AAA_33 PF13671.6 EGR34108.1 - 4e-06 27.1 0.0 7.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGR34108.1 - 2.7e-05 23.9 3.4 0.0058 16.3 0.1 2.6 3 0 0 3 3 3 2 Thymidylate kinase dNK PF01712.19 EGR34108.1 - 0.005 16.7 0.1 0.017 15.0 0.0 1.9 2 0 0 2 2 2 1 Deoxynucleoside kinase Zeta_toxin PF06414.12 EGR34108.1 - 0.011 15.0 0.2 0.036 13.3 0.0 1.9 2 1 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 EGR34108.1 - 0.011 16.1 1.1 1.8 9.0 0.0 3.0 2 1 0 2 2 2 0 RNA helicase AAA PF00004.29 EGR34108.1 - 0.012 16.1 0.0 0.19 12.2 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EGR34108.1 - 0.11 12.8 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2756 PF10956.8 EGR34108.1 - 7.9 7.0 7.6 0.26 11.8 1.4 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF2756) DAGK_cat PF00781.24 EGR34109.1 - 7.8e-17 61.1 0.3 1.8e-16 59.9 0.2 1.7 1 1 0 1 1 1 1 Diacylglycerol kinase catalytic domain DAGK_acc PF00609.19 EGR34109.1 - 1.2e-15 58.2 1.7 5.2e-15 56.1 1.7 2.1 1 1 0 1 1 1 1 Diacylglycerol kinase accessory domain Ins_P5_2-kin PF06090.12 EGR34109.1 - 0.011 15.3 0.9 0.014 14.9 0.9 1.1 1 0 0 1 1 1 0 Inositol-pentakisphosphate 2-kinase Hormone_4 PF00220.17 EGR34109.1 - 0.089 12.8 1.1 0.21 11.6 1.1 1.7 1 0 0 1 1 1 0 Neurohypophysial hormones, N-terminal Domain ACBP PF00887.19 EGR34110.1 - 1.5e-27 95.6 0.7 1.7e-27 95.4 0.7 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein Ribosomal_L3 PF00297.22 EGR34111.1 - 1.2e-18 67.3 3.5 9.4e-17 61.0 0.8 3.3 1 1 0 2 2 2 2 Ribosomal protein L3 Sm_like PF16243.5 EGR34112.1 - 0.0039 17.3 0.3 0.0075 16.4 0.3 1.6 1 0 0 1 1 1 1 Sm_like domain Sugarporin_N PF11471.8 EGR34113.1 - 0.0063 16.4 0.1 0.01 15.7 0.1 1.3 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension TIP120 PF08623.10 EGR34114.1 - 4.3e-13 49.4 0.1 4.3e-13 49.4 0.1 5.2 4 2 0 4 4 4 1 TATA-binding protein interacting (TIP20) HEAT PF02985.22 EGR34114.1 - 2.4e-11 42.8 4.3 0.13 12.6 0.0 7.9 8 0 0 8 8 8 3 HEAT repeat HEAT_2 PF13646.6 EGR34114.1 - 1.3e-06 28.7 0.1 0.095 13.1 0.0 4.7 4 0 0 4 4 4 1 HEAT repeats RTP1_C1 PF10363.9 EGR34114.1 - 3e-05 24.2 3.3 0.003 17.7 0.7 5.2 4 3 1 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_EZ PF13513.6 EGR34114.1 - 7.3e-05 23.2 0.3 0.22 12.1 0.0 4.5 5 0 0 5 5 5 1 HEAT-like repeat UME PF08064.13 EGR34114.1 - 0.0077 16.1 14.3 2.1 8.3 0.3 6.6 7 1 0 7 7 7 2 UME (NUC010) domain DUF5071 PF16804.5 EGR34114.1 - 0.18 12.0 9.3 2.3 8.5 0.0 5.1 5 1 0 5 5 5 0 Domain of unknown function (DUF5071) RasGEF_N_2 PF14663.6 EGR34114.1 - 0.67 10.4 8.2 0.41 11.1 0.2 4.7 5 0 0 5 5 5 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Ras PF00071.22 EGR34115.1 - 8.3e-53 178.3 1.9 1.2e-52 177.8 1.9 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR34115.1 - 5.7e-32 110.5 0.8 1.2e-31 109.5 0.8 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR34115.1 - 3.8e-12 46.0 0.2 5.7e-12 45.4 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family FeoB_N PF02421.18 EGR34115.1 - 2.2e-05 24.1 0.2 8.4e-05 22.1 0.2 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EGR34115.1 - 2.5e-05 24.3 0.1 4.3e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGR34115.1 - 9.7e-05 22.0 0.5 0.00043 19.9 0.3 2.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGR34115.1 - 0.086 12.7 0.0 5.4 6.9 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase FA_desaturase PF00487.24 EGR34116.1 - 6.2e-27 95.0 15.8 1e-26 94.3 15.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF4731 PF15875.5 EGR34116.1 - 0.012 15.8 0.2 0.66 10.2 0.0 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4731) zinc_ribbon_15 PF17032.5 EGR34116.1 - 0.13 13.1 0.4 0.39 11.5 0.0 2.0 2 0 0 2 2 2 0 zinc-ribbon family CTP_transf_1 PF01148.20 EGR34119.1 - 0.023 14.4 0.3 0.027 14.2 0.3 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family DUF3800 PF12686.7 EGR34119.1 - 1.5 9.4 4.4 2.3 8.9 4.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) Ribosomal_L37e PF01907.19 EGR34120.1 - 6.8e-25 87.0 8.7 7.5e-25 86.9 8.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L37e DUF1258 PF06869.12 EGR34120.1 - 0.00069 19.2 0.1 0.00069 19.2 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1258) HypA PF01155.19 EGR34120.1 - 0.0066 16.5 0.5 0.0071 16.4 0.5 1.1 1 0 0 1 1 1 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-RING_10 PF16685.5 EGR34120.1 - 0.017 15.2 0.8 0.019 15.1 0.8 1.1 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF2616 PF11077.8 EGR34120.1 - 0.032 14.0 0.1 0.034 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) zf-Mss51 PF13824.6 EGR34120.1 - 0.036 14.1 2.2 1.7 8.8 2.2 2.1 1 1 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_2 PF13240.6 EGR34120.1 - 0.039 13.7 2.4 1.4 8.8 0.1 2.2 1 1 1 2 2 2 0 zinc-ribbon domain DUF2688 PF10892.8 EGR34120.1 - 0.32 10.5 4.5 2.6 7.6 2.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2688) PriA_CRR PF18319.1 EGR34120.1 - 0.33 11.0 7.4 0.63 10.1 5.7 2.2 1 1 1 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain zf-C3HC4 PF00097.25 EGR34120.1 - 0.37 10.7 4.3 0.5 10.3 4.3 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PSS PF03034.15 EGR34121.1 - 4.5e-94 315.2 16.5 7.1e-94 314.6 16.5 1.3 1 0 0 1 1 1 1 Phosphatidyl serine synthase LPG_synthase_TM PF03706.13 EGR34121.1 - 0.011 15.4 3.8 0.45 10.0 0.1 2.4 2 0 0 2 2 2 0 Lysylphosphatidylglycerol synthase TM region LapA_dom PF06305.11 EGR34121.1 - 0.27 11.1 10.7 0.26 11.1 0.3 3.7 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain MORN PF02493.20 EGR34122.1 - 1.7e-55 181.7 85.6 1.2e-08 34.4 2.0 9.8 10 0 0 10 10 10 9 MORN repeat DUF448 PF04296.13 EGR34122.1 - 0.0034 17.2 5.5 0.6 10.0 0.0 3.7 3 1 1 4 4 4 2 Protein of unknown function (DUF448) DUF3048_C PF17479.2 EGR34122.1 - 0.58 10.6 28.0 0.34 11.3 2.9 5.1 1 1 3 4 4 4 0 Protein of unknown function (DUF3048) C-terminal domain Ig_mannosidase PF17753.1 EGR34122.1 - 3.8 7.3 6.6 4.8 7.0 0.2 3.5 5 0 0 5 5 5 0 Ig-fold domain MORN PF02493.20 EGR34123.1 - 2e-38 128.0 68.7 6.7e-08 32.0 1.6 10.2 10 0 0 10 10 10 9 MORN repeat DUF523 PF04463.12 EGR34123.1 - 4.6 7.3 6.2 5.8 7.0 0.0 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF523) Got1 PF04178.12 EGR34124.1 - 1.1e-06 29.0 2.9 2.2e-06 28.1 2.9 1.5 1 1 1 2 2 2 2 Got1/Sft2-like family K1 PF02960.14 EGR34124.1 - 0.039 14.0 0.5 0.056 13.6 0.5 1.3 1 1 0 1 1 1 0 K1 glycoprotein Epimerase PF01370.21 EGR34125.1 - 1.8e-07 30.9 0.1 6.2e-07 29.1 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Peptidase_C1 PF00112.23 EGR34126.1 - 2.1e-68 230.7 2.8 3.9e-68 229.8 2.8 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGR34126.1 - 7.6e-10 39.1 5.8 1.4e-09 38.2 5.8 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGR34126.1 - 4.6e-05 22.4 0.8 0.011 14.5 0.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Yuri_gagarin PF15934.5 EGR34126.1 - 0.1 12.4 3.6 0.23 11.3 3.6 1.5 1 0 0 1 1 1 0 Yuri gagarin FidL_like PF15941.5 EGR34126.1 - 0.43 11.0 5.0 0.54 10.7 2.2 2.2 2 0 0 2 2 2 0 FidL-like putative membrane protein CH_2 PF06294.11 EGR34127.1 - 4.9e-21 74.7 2.1 7.1e-20 70.9 2.1 3.0 1 1 0 1 1 1 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 EGR34127.1 - 4.1e-08 32.9 0.0 3e-07 30.2 0.0 2.5 1 0 0 1 1 1 1 CAMSAP CH domain DUF3108 PF11306.8 EGR34127.1 - 0.031 14.2 0.1 0.099 12.6 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3108) SAUGI PF06106.11 EGR34127.1 - 0.036 14.6 1.0 0.17 12.4 0.1 2.6 2 0 0 2 2 2 0 S. aureus uracil DNA glycosylase inhibitor TIR_3 PF18567.1 EGR34127.1 - 0.69 9.9 9.6 0.11 12.5 0.7 3.7 3 1 0 4 4 4 0 Toll/interleukin-1 receptor domain Myosin_head PF00063.21 EGR34128.1 - 5.9e-83 279.3 28.0 7.5e-83 278.9 28.0 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) HEM4 PF02602.15 EGR34128.1 - 0.19 11.1 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Uroporphyrinogen-III synthase HemD Myosin_head PF00063.21 EGR34129.1 - 2.5e-38 131.8 0.9 3.1e-38 131.5 0.9 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) DNA_pol3_delta2 PF13177.6 EGR34129.1 - 0.0039 17.0 1.4 0.0054 16.5 0.1 1.8 2 0 0 2 2 2 1 DNA polymerase III, delta subunit RNA_helicase PF00910.22 EGR34129.1 - 0.042 14.2 2.4 0.87 10.0 0.0 2.9 2 1 1 3 3 3 0 RNA helicase AAA_22 PF13401.6 EGR34129.1 - 0.044 14.1 0.1 0.15 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGR34129.1 - 0.15 12.6 1.8 0.32 11.5 0.6 2.1 2 1 0 2 2 2 0 ABC transporter Helicase_C PF00271.31 EGR34130.1 - 5.2e-09 36.4 0.2 5.2e-09 36.4 0.2 3.0 3 1 0 3 3 3 1 Helicase conserved C-terminal domain ArsD PF06953.11 EGR34130.1 - 0.013 15.9 4.0 0.3 11.4 0.1 2.6 2 0 0 2 2 2 0 Arsenical resistance operon trans-acting repressor ArsD Pkinase PF00069.25 EGR34131.1 - 1.9e-65 220.8 0.2 3.7e-65 219.9 0.2 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34131.1 - 6.9e-31 107.5 0.1 1.3e-30 106.6 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR34131.1 - 3.7e-06 26.1 1.2 1.9e-05 23.8 1.2 2.1 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGR34131.1 - 3.2e-05 23.4 1.0 0.05 12.9 0.0 3.0 2 1 1 3 3 3 2 Kinase-like WD40 PF00400.32 EGR34131.1 - 4.4e-05 24.2 2.8 0.33 11.9 0.0 5.3 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR34131.1 - 5.3e-05 23.4 2.9 0.081 13.2 0.1 4.5 2 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain FTA2 PF13095.6 EGR34131.1 - 0.0053 16.4 1.9 1.8 8.1 0.1 2.7 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGR34131.1 - 0.049 13.6 0.0 0.13 12.2 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Hemopexin PF00045.19 EGR34132.1 - 0.13 12.2 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Hemopexin Collagen_mid PF15984.5 EGR34133.1 - 0.00035 20.4 8.8 0.0016 18.3 8.8 1.8 1 1 0 1 1 1 1 Bacterial collagen, middle region Wound_ind PF08186.11 EGR34133.1 - 0.011 16.1 0.0 0.03 14.8 0.0 1.8 1 0 0 1 1 1 0 Wound-inducible basic protein family MSP1b PF03429.13 EGR34133.1 - 0.012 13.8 3.0 0.19 9.8 0.2 2.0 1 1 1 2 2 2 0 Major surface protein 1B Chlorosome_CsmC PF11098.8 EGR34133.1 - 0.3 11.1 4.2 0.55 10.2 3.6 1.6 1 1 0 1 1 1 0 Chlorosome envelope protein C CENP-B_dimeris PF09026.10 EGR34133.1 - 0.35 11.3 5.3 0.62 10.5 5.3 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Ribosomal_L7Ae PF01248.26 EGR34134.1 - 1.2e-18 66.6 1.5 1.9e-18 66.0 1.5 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Kri1 PF05178.12 EGR34134.1 - 0.046 14.3 2.0 0.046 14.3 2.0 1.9 2 0 0 2 2 2 0 KRI1-like family SPOC PF07744.13 EGR34134.1 - 0.053 13.4 0.1 0.075 13.0 0.1 1.3 1 0 0 1 1 1 0 SPOC domain VSP PF03302.13 EGR34135.1 - 0.03 13.2 81.2 0.1 11.5 16.9 4.2 1 1 3 4 4 4 0 Giardia variant-specific surface protein RRM_1 PF00076.22 EGR34136.1 - 1.3e-05 24.9 0.0 3.3e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 EGR34136.1 - 0.00064 19.6 0.7 0.0018 18.2 0.0 2.1 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif AMPK1_CBM PF16561.5 EGR34137.1 - 2e-42 143.3 8.4 1.1e-25 89.7 2.4 2.6 2 0 0 2 2 2 2 Glycogen recognition site of AMP-activated protein kinase Kelch_4 PF13418.6 EGR34137.1 - 2.7e-29 100.9 0.2 9.6e-07 28.7 0.0 5.9 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EGR34137.1 - 1.3e-27 95.5 0.1 0.00011 22.3 0.0 6.0 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 EGR34137.1 - 8.6e-26 89.3 0.0 7.4e-06 25.4 0.0 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 EGR34137.1 - 8e-25 86.4 1.1 7.6e-05 22.6 0.0 5.7 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 EGR34137.1 - 2.1e-24 84.9 8.2 0.00022 21.4 0.1 6.7 4 1 2 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EGR34137.1 - 3.9e-22 77.3 1.5 1.5e-05 24.8 0.0 6.2 6 0 0 6 6 6 4 Kelch motif CBM53 PF16760.5 EGR34137.1 - 0.037 14.6 12.3 0.062 13.9 3.4 2.9 3 0 0 3 3 3 0 Starch/carbohydrate-binding module (family 53) DUF5625 PF18539.1 EGR34137.1 - 0.19 12.0 2.1 0.37 11.1 0.3 2.4 3 1 0 3 3 3 0 Domain of unknown function (DUF5625) Chitin_synth_2 PF03142.15 EGR34138.1 - 1.7e-24 86.4 0.3 1.7e-24 86.4 0.3 2.2 1 1 0 2 2 2 2 Chitin synthase Glyco_trans_2_3 PF13632.6 EGR34138.1 - 2e-10 40.9 2.3 5e-10 39.6 2.3 1.8 1 1 0 1 1 1 1 Glycosyl transferase family group 2 DUF2534 PF10749.9 EGR34138.1 - 1 9.6 11.1 0.11 12.7 5.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2534) Tmpp129 PF10272.9 EGR34138.1 - 1 8.6 7.2 2.6 7.3 7.0 1.7 1 1 0 1 1 1 0 Putative transmembrane protein precursor PIRT PF15099.6 EGR34138.1 - 3 7.4 5.1 1.8 8.1 2.3 1.9 1 1 1 2 2 2 0 Phosphoinositide-interacting protein family CBFD_NFYB_HMF PF00808.23 EGR34139.1 - 1e-19 70.6 0.1 2.4e-19 69.4 0.1 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGR34139.1 - 1.1e-15 58.2 0.3 2e-15 57.3 0.3 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 DivIC PF04977.15 EGR34139.1 - 0.0011 18.6 0.5 0.0041 16.8 0.5 1.9 1 0 0 1 1 1 1 Septum formation initiator TPR_7 PF13176.6 EGR34140.1 - 0.0025 17.7 0.1 0.0077 16.2 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGR34140.1 - 0.0027 17.7 0.1 0.0084 16.2 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGR34140.1 - 0.0028 17.7 0.2 0.011 15.9 0.2 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat DUF1926 PF09095.11 EGR34140.1 - 0.0033 17.1 1.1 0.0036 17.0 1.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1926) TPR_12 PF13424.6 EGR34140.1 - 0.006 16.9 0.0 0.0092 16.3 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGR34140.1 - 0.0077 16.0 0.0 0.022 14.6 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGR34140.1 - 0.034 13.3 0.1 0.042 13.1 0.1 1.1 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF4665 PF15679.5 EGR34140.1 - 0.063 13.9 1.4 0.096 13.3 1.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) TPR_10 PF13374.6 EGR34140.1 - 0.082 12.8 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat EF-hand_6 PF13405.6 EGR34141.1 - 0.00076 19.2 1.3 0.43 10.6 0.0 3.6 3 1 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EGR34141.1 - 0.36 11.3 7.7 51 4.4 7.7 3.2 1 1 0 1 1 1 0 EF-hand domain pair Arm PF00514.23 EGR34142.1 - 0.0016 18.4 0.3 0.063 13.3 0.0 2.9 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat Fis1_TPR_N PF14852.6 EGR34142.1 - 0.026 14.2 0.1 0.12 12.1 0.0 2.0 2 0 0 2 2 2 0 Fis1 N-terminal tetratricopeptide repeat Asparaginase PF00710.20 EGR34143.1 - 3.6e-54 183.2 0.0 6.3e-54 182.4 0.0 1.4 1 0 0 1 1 1 1 Asparaginase, N-terminal Ank_2 PF12796.7 EGR34143.1 - 4.4e-22 78.5 0.5 8.7e-09 35.9 0.1 3.6 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Asparaginase_C PF17763.1 EGR34143.1 - 1.4e-19 70.4 0.0 3.1e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Ank_4 PF13637.6 EGR34143.1 - 6.6e-14 52.1 0.2 5.8e-05 23.6 0.0 4.1 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR34143.1 - 4.8e-10 38.8 0.2 0.036 14.6 0.0 5.8 6 0 0 6 6 6 2 Ankyrin repeat Ank PF00023.30 EGR34143.1 - 4.2e-08 33.3 0.0 0.078 13.5 0.0 4.7 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 EGR34143.1 - 4.9e-08 33.1 0.0 0.0069 16.7 0.1 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) PX PF00787.24 EGR34144.1 - 6.1e-22 77.7 0.2 2.2e-21 75.9 0.2 2.0 1 0 0 1 1 1 1 PX domain VWA PF00092.28 EGR34145.1 - 1.6e-24 87.1 2.1 2.2e-24 86.7 0.4 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGR34145.1 - 2.7e-18 66.6 0.6 1.8e-16 60.7 0.1 2.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_3 PF13768.6 EGR34145.1 - 9.6e-18 64.6 0.1 2.4e-17 63.3 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EGR34145.1 - 4.4e-05 23.0 0.0 6.4e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein Peptidase_S49_N PF08496.10 EGR34145.1 - 0.019 15.0 1.2 0.019 15.0 1.2 2.6 2 1 0 2 2 2 0 Peptidase family S49 N-terminal DUF2201 PF09967.9 EGR34145.1 - 0.041 14.0 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 VWA-like domain (DUF2201) Bin3 PF06859.12 EGR34145.1 - 0.12 13.0 0.1 0.12 13.0 0.1 3.7 4 1 0 4 4 4 0 Bicoid-interacting protein 3 (Bin3) Patched PF02460.18 EGR34146.1 - 5.9 4.8 8.5 6.1 4.8 8.5 1.2 1 0 0 1 1 1 0 Patched family GCP_C_terminal PF04130.13 EGR34147.1 - 2.5e-74 250.5 15.6 4.1e-74 249.8 15.6 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EGR34147.1 - 4.3e-44 151.4 5.0 4.3e-44 151.4 5.0 3.0 3 1 0 3 3 3 1 Gamma tubulin complex component N-terminal BSD PF03909.17 EGR34148.1 - 0.032 14.2 1.2 0.12 12.4 0.1 2.6 3 0 0 3 3 3 0 BSD domain DHC_N2 PF08393.13 EGR34149.1 - 1.9e-91 307.1 16.2 1.9e-91 307.1 16.2 4.7 1 1 1 4 4 4 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 EGR34150.1 - 6.5e-150 498.6 0.1 3.4e-149 496.3 0.1 2.4 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGR34150.1 - 8.9e-116 387.3 29.6 8.9e-116 387.3 29.6 5.9 4 2 1 5 5 4 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 EGR34150.1 - 4.3e-113 378.9 32.0 4.3e-113 378.9 32.0 4.0 4 2 0 4 4 2 1 Dynein heavy chain, N-terminal region 1 AAA_7 PF12775.7 EGR34150.1 - 3e-31 108.3 0.8 2.6e-24 85.7 0.0 4.0 3 0 0 3 3 3 3 P-loop containing dynein motor region AAA_5 PF07728.14 EGR34150.1 - 2.2e-21 76.3 0.5 2e-08 34.3 0.0 6.0 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 EGR34150.1 - 2.8e-21 75.9 0.0 5.4e-20 71.8 0.0 3.5 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_16 PF13191.6 EGR34150.1 - 3.6e-08 34.0 3.5 0.15 12.4 0.0 5.9 6 1 1 7 7 7 3 AAA ATPase domain AAA_22 PF13401.6 EGR34150.1 - 4.2e-08 33.6 6.4 0.096 13.0 0.0 6.0 6 1 0 6 6 5 2 AAA domain AAA PF00004.29 EGR34150.1 - 2.8e-07 31.0 2.3 0.099 13.1 0.0 5.3 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGR34150.1 - 9e-05 23.0 7.0 0.28 11.7 0.0 5.5 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.6 EGR34150.1 - 0.00011 21.9 0.1 0.027 14.2 0.1 3.0 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_30 PF13604.6 EGR34150.1 - 0.00013 21.8 0.1 0.17 11.6 0.0 3.2 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 EGR34150.1 - 0.00036 20.5 3.1 0.02 14.8 0.0 3.9 4 0 0 4 4 2 1 RsgA GTPase AAA_33 PF13671.6 EGR34150.1 - 0.0023 18.1 0.0 1.3 9.2 0.0 3.8 3 0 0 3 3 3 1 AAA domain CNOT11 PF10155.9 EGR34150.1 - 0.007 16.5 0.7 0.041 14.0 0.7 2.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 AAA_28 PF13521.6 EGR34150.1 - 0.0075 16.5 1.4 0.95 9.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EGR34150.1 - 0.0077 16.6 4.9 26 5.3 0.0 5.2 5 0 0 5 5 4 0 RNA helicase FtsK_SpoIIIE PF01580.18 EGR34150.1 - 0.0083 15.5 0.6 0.39 10.0 0.1 3.6 3 0 0 3 3 3 1 FtsK/SpoIIIE family T2SSE PF00437.20 EGR34150.1 - 0.01 14.9 0.4 0.094 11.8 0.0 2.6 3 0 0 3 3 3 0 Type II/IV secretion system protein Cytidylate_kin PF02224.18 EGR34150.1 - 0.015 15.1 0.0 4.3 7.0 0.0 3.1 2 0 0 2 2 2 0 Cytidylate kinase ABC_tran PF00005.27 EGR34150.1 - 0.074 13.6 0.0 0.074 13.6 0.0 6.1 7 1 0 7 7 4 0 ABC transporter Glutaredoxin2_C PF04399.13 EGR34150.1 - 0.17 11.7 9.8 0.99 9.2 0.8 4.6 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain AAA_25 PF13481.6 EGR34150.1 - 0.18 11.4 0.2 10 5.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.19 EGR34150.1 - 0.44 9.9 0.0 0.44 9.9 0.0 2.6 2 1 0 2 2 1 0 RecF/RecN/SMC N terminal domain AAA_19 PF13245.6 EGR34150.1 - 0.79 10.0 6.4 47 4.3 0.1 4.7 5 0 0 5 5 3 0 AAA domain Claudin_3 PF06653.11 EGR34151.1 - 0.78 9.7 12.2 0.06 13.3 5.3 1.9 1 1 1 2 2 2 0 Tight junction protein, Claudin-like Vpu PF00558.19 EGR34151.1 - 0.92 9.3 6.4 2.8 7.8 0.6 2.4 2 0 0 2 2 2 0 Vpu protein DUF2530 PF10745.9 EGR34151.1 - 1.4 9.2 4.4 1.8 8.9 2.8 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2530) ODV-E18 PF10717.9 EGR34151.1 - 2.8 7.9 13.2 0.42 10.5 1.5 2.1 1 1 1 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 TMEM154 PF15102.6 EGR34151.1 - 4.8 7.1 9.9 0.5 10.3 0.7 2.1 1 1 1 2 2 2 0 TMEM154 protein family HXXEE PF13787.6 EGR34151.1 - 8 7.3 9.4 22 5.9 9.4 1.7 1 1 0 1 1 1 0 Protein of unknown function with HXXEE motif ABC_tran PF00005.27 EGR34152.1 - 1.1e-51 174.9 4.6 1e-26 94.1 0.1 3.4 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 EGR34152.1 - 3.2e-16 60.0 2.4 0.0008 19.3 0.0 4.7 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EGR34152.1 - 7.2e-08 31.9 46.2 8e-08 31.8 44.3 2.1 1 1 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EGR34152.1 - 0.00024 21.0 6.5 0.16 11.8 0.2 3.0 3 0 0 3 3 3 2 RsgA GTPase AAA_29 PF13555.6 EGR34152.1 - 0.0035 17.0 2.9 1.1 9.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_27 PF13514.6 EGR34152.1 - 0.0037 16.9 0.9 0.34 10.5 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGR34152.1 - 0.004 16.9 0.1 0.097 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain SRP54 PF00448.22 EGR34152.1 - 0.019 14.6 1.8 0.043 13.4 0.3 2.2 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain SbcCD_C PF13558.6 EGR34152.1 - 0.03 14.5 0.1 0.67 10.2 0.0 3.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit LPG_synthase_TM PF03706.13 EGR34152.1 - 0.042 13.4 0.5 0.079 12.5 0.5 1.4 1 0 0 1 1 1 0 Lysylphosphatidylglycerol synthase TM region AAA PF00004.29 EGR34152.1 - 0.083 13.3 2.2 24 5.4 1.1 3.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EGR34152.1 - 0.11 12.6 2.5 11 6.1 0.2 2.9 3 0 0 3 3 3 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 EGR34152.1 - 0.16 11.3 0.1 1.2 8.3 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin SMC_N PF02463.19 EGR34152.1 - 0.25 10.8 17.0 0.31 10.4 3.5 4.7 3 2 0 4 4 4 0 RecF/RecN/SMC N terminal domain DUF4162 PF13732.6 EGR34152.1 - 2.5 8.9 14.1 0.7 10.7 1.1 4.4 3 2 0 3 3 3 0 Domain of unknown function (DUF4162) FeoB_N PF02421.18 EGR34152.1 - 3.6 7.1 5.5 17 4.9 0.1 3.2 3 0 0 3 3 3 0 Ferrous iron transport protein B p450 PF00067.22 EGR34154.1 - 3.7e-46 157.8 0.1 4.7e-46 157.5 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_C92 PF05708.12 EGR34155.1 - 0.00028 21.0 0.2 0.39 10.8 0.0 2.3 1 1 1 2 2 2 2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family MORN PF02493.20 EGR34156.1 - 8.3e-32 107.2 44.4 3.9e-07 29.6 2.4 7.3 7 0 0 7 7 7 7 MORN repeat ATPase_gene1 PF09527.10 EGR34156.1 - 0.24 11.6 3.7 0.4 10.9 0.2 2.4 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter TPR_1 PF00515.28 EGR34157.1 - 4.3e-10 39.0 5.3 6.9e-05 22.5 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGR34157.1 - 1.1e-07 31.4 1.4 0.009 16.1 0.0 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGR34157.1 - 0.0002 21.3 3.6 0.47 10.8 0.2 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGR34157.1 - 0.0025 18.0 0.3 0.67 10.3 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGR34157.1 - 0.032 14.7 0.5 0.16 12.5 0.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR34157.1 - 0.034 14.3 1.7 0.11 12.7 1.7 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EGR34157.1 - 0.11 12.9 2.8 2.7 8.6 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.18 EGR34157.1 - 0.16 12.0 4.1 1.3 9.1 1.0 2.9 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain Peptidase_M8 PF01457.16 EGR34158.1 - 0.00065 18.5 0.0 0.0017 17.1 0.0 1.6 1 1 1 2 2 2 1 Leishmanolysin Peptidase_M8 PF01457.16 EGR34159.1 - 5.9e-30 104.5 12.8 5.5e-26 91.4 0.9 2.0 1 1 1 2 2 2 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR34159.1 - 0.0066 16.5 1.1 0.025 14.6 1.1 2.1 1 0 0 1 1 1 1 Tenascin EGF domain Peptidase_M8 PF01457.16 EGR34160.1 - 1.8e-23 83.1 1.2 2.8e-23 82.4 1.1 1.4 1 1 0 1 1 1 1 Leishmanolysin DsrD PF08679.11 EGR34160.1 - 0.089 13.1 1.6 1.3 9.3 0.9 2.4 2 0 0 2 2 2 0 Dissimilatory sulfite reductase D (DsrD) Shugoshin_C PF07557.11 EGR34160.1 - 0.14 12.0 0.2 0.14 12.0 0.2 1.7 2 0 0 2 2 2 0 Shugoshin C terminus Gon7 PF08738.10 EGR34161.1 - 4.3 7.5 6.7 9.5 6.4 6.7 1.5 1 0 0 1 1 1 0 Gon7 family Tcp10_C PF07202.13 EGR34162.1 - 3.2e-29 102.1 7.1 3.2e-29 102.1 7.1 2.2 2 1 0 2 2 2 1 T-complex protein 10 C-terminus Tudor_3 PF18115.1 EGR34162.1 - 0.013 15.3 0.3 0.64 9.9 0.0 3.4 3 1 0 3 3 3 0 DNA repair protein Crb2 Tudor domain DUF3471 PF11954.8 EGR34162.1 - 0.039 14.4 1.3 0.36 11.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3471) MORN_2 PF07661.13 EGR34162.1 - 0.057 13.7 7.3 4.3 7.9 0.0 5.4 5 0 0 5 5 5 0 MORN repeat variant HycA_repressor PF11046.8 EGR34165.1 - 0.014 15.6 1.1 0.037 14.2 1.1 1.8 1 0 0 1 1 1 0 Transcriptional repressor of hyc and hyp operons Abhydrolase_1 PF00561.20 EGR34165.1 - 0.049 13.3 0.2 0.14 11.8 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGR34165.1 - 0.072 12.4 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGR34165.1 - 0.13 11.7 0.0 0.3 10.5 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pkinase PF00069.25 EGR34166.1 - 6.3e-70 235.6 0.7 7.1e-70 235.4 0.7 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34166.1 - 5.5e-39 134.0 0.1 6.6e-39 133.7 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR34166.1 - 0.00032 20.1 0.0 0.00056 19.3 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR34166.1 - 0.00062 18.6 0.0 0.00092 18.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Sigma_reg_C PF13791.6 EGR34166.1 - 0.067 13.4 0.3 0.5 10.6 0.0 2.5 3 1 1 4 4 4 0 Sigma factor regulator C-terminal FTA2 PF13095.6 EGR34166.1 - 0.072 12.7 0.2 0.13 11.9 0.2 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGR34166.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Myb_DNA-binding PF00249.31 EGR34167.1 - 1.1e-24 86.4 12.1 2.5e-12 46.8 0.2 4.9 4 1 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGR34167.1 - 5.1e-17 61.9 31.0 3.3e-10 40.1 2.1 4.6 2 1 2 4 4 4 3 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EGR34167.1 - 0.0016 18.6 0.2 0.0016 18.6 0.2 4.1 2 1 2 4 4 4 1 SANT/Myb-like domain of DAMP1 3HCDH_N PF02737.18 EGR34167.1 - 0.055 13.3 0.0 0.055 13.3 0.0 2.7 2 2 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain OST3_OST6 PF04756.13 EGR34169.1 - 6.9e-45 153.6 13.1 9.9e-45 153.1 13.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family UQ_con PF00179.26 EGR34169.1 - 2e-34 118.2 0.2 5.4e-34 116.8 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Thioredoxin PF00085.20 EGR34169.1 - 0.088 12.8 0.0 0.22 11.5 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin SPC25 PF06703.11 EGR34169.1 - 0.63 9.8 10.8 0.15 11.9 4.4 2.6 3 0 0 3 3 3 0 Microsomal signal peptidase 25 kDa subunit (SPC25) CbiQ PF02361.16 EGR34169.1 - 5.7 6.5 10.4 9.3 5.8 10.4 1.3 1 0 0 1 1 1 0 Cobalt transport protein UPF0449 PF15136.6 EGR34171.1 - 0.74 10.3 5.6 0.57 10.7 2.7 1.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 DUF4485 PF14846.6 EGR34171.1 - 3.4 7.8 13.4 1.8 8.6 8.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4485) Rhodanese PF00581.20 EGR34172.1 - 2.6e-16 60.0 3.4 5.3e-10 39.8 0.1 2.4 2 0 0 2 2 2 2 Rhodanese-like domain HJURP_C PF12347.8 EGR34172.1 - 0.084 12.9 0.7 0.21 11.6 0.7 1.7 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat RRM_1 PF00076.22 EGR34174.1 - 2.5e-31 107.3 1.8 3.4e-15 55.6 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET_assoc PF11767.8 EGR34174.1 - 1.4e-05 24.6 4.3 0.063 12.9 0.3 3.2 3 0 0 3 3 3 2 Histone lysine methyltransferase SET associated RRM_occluded PF16842.5 EGR34174.1 - 6.6e-05 22.7 0.4 0.033 14.1 0.0 2.8 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_7 PF16367.5 EGR34174.1 - 0.00034 20.7 0.2 0.012 15.8 0.0 3.3 3 0 0 3 3 3 1 RNA recognition motif RBM39linker PF15519.6 EGR34174.1 - 0.001 20.1 0.0 0.001 20.1 0.0 4.6 3 1 0 3 3 3 1 linker between RRM2 and RRM3 domains in RBM39 protein DUF1866 PF08952.11 EGR34174.1 - 0.017 14.9 0.5 0.049 13.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) SNF PF00209.18 EGR34175.1 - 3.2e-43 148.2 14.3 3.2e-43 148.2 14.3 2.9 2 2 0 2 2 2 1 Sodium:neurotransmitter symporter family MORN PF02493.20 EGR34177.1 - 5e-12 45.0 21.3 0.00015 21.5 0.4 4.8 4 0 0 4 4 4 4 MORN repeat Collagen PF01391.18 EGR34177.1 - 1.1e-09 38.0 31.4 4.3e-09 36.0 31.4 2.0 1 1 0 1 1 1 1 Collagen triple helix repeat (20 copies) eIF2_C PF09173.11 EGR34178.1 - 3.2e-28 97.8 0.4 7.9e-28 96.5 0.4 1.7 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EGR34178.1 - 7.3e-23 81.1 1.3 4.9e-22 78.4 1.3 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EGR34178.1 - 6.2e-10 39.3 0.5 2e-09 37.7 0.5 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGR34178.1 - 0.00029 20.9 0.1 0.0014 18.7 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGR34178.1 - 0.064 12.4 0.1 0.18 11.0 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit IBR PF01485.21 EGR34178.1 - 0.55 10.5 6.6 0.44 10.8 0.4 2.7 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain dCMP_cyt_deam_1 PF00383.23 EGR34179.1 - 1.2e-14 54.0 0.4 1.5e-14 53.7 0.4 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EGR34179.1 - 4.7e-09 36.6 0.2 7.7e-07 29.4 0.1 2.1 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EGR34179.1 - 0.0012 18.4 0.8 0.018 14.6 0.0 2.0 1 1 1 2 2 2 1 A distinct subfamily of CDD/CDA-like deaminases EAV_GS PF01309.18 EGR34179.1 - 0.12 12.0 0.0 0.27 10.8 0.0 1.5 1 1 0 2 2 2 0 Equine arteritis virus small envelope glycoprotein HEAT_2 PF13646.6 EGR34180.1 - 4e-30 104.0 0.0 1e-11 45.0 0.0 6.1 5 2 2 7 7 7 3 HEAT repeats HEAT PF02985.22 EGR34180.1 - 1e-28 96.9 0.1 0.0002 21.3 0.0 8.7 9 0 0 9 9 9 6 HEAT repeat HEAT_EZ PF13513.6 EGR34180.1 - 7.8e-17 61.4 2.3 0.00034 21.0 0.0 7.6 8 1 0 8 8 7 3 HEAT-like repeat Cnd1 PF12717.7 EGR34180.1 - 3.5e-15 56.4 0.0 2.8e-07 30.7 0.0 4.4 1 1 2 3 3 3 3 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 EGR34180.1 - 8e-10 38.4 2.3 0.096 12.8 0.1 6.4 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.16 EGR34180.1 - 3e-09 36.7 6.1 0.026 15.2 0.0 6.1 6 0 0 6 6 5 3 PBS lyase HEAT-like repeat Vitellogenin_N PF01347.22 EGR34180.1 - 0.00062 18.3 0.1 0.0014 17.2 0.1 1.6 1 0 0 1 1 1 1 Lipoprotein amino terminal region TPR_18 PF13512.6 EGR34180.1 - 0.0011 19.1 0.3 0.012 15.7 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat RTP1_C1 PF10363.9 EGR34180.1 - 0.0026 17.9 0.0 5.8 7.1 0.0 3.7 2 1 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Cohesin_HEAT PF12765.7 EGR34180.1 - 0.011 16.0 0.5 1.5e+02 2.8 0.0 4.9 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion TIP120 PF08623.10 EGR34180.1 - 0.011 15.5 0.0 7 6.4 0.0 3.8 3 1 1 4 4 4 0 TATA-binding protein interacting (TIP20) adh_short PF00106.25 EGR34181.1 - 5e-20 71.8 0.0 6.7e-20 71.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGR34181.1 - 3.2e-18 66.2 0.0 4e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGR34181.1 - 2.1e-05 24.5 0.0 3e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Vps16_N PF04841.13 EGR34183.1 - 1.1e-40 139.7 4.9 1.1e-40 139.7 4.9 1.8 2 0 0 2 2 2 1 Vps16, N-terminal region Vps16_C PF04840.12 EGR34183.1 - 1.9e-12 46.9 30.0 8.1e-12 44.8 30.0 2.1 1 1 0 1 1 1 1 Vps16, C-terminal region RasGEF_N_2 PF14663.6 EGR34184.1 - 1.8e-25 89.5 9.0 2.2e-25 89.1 3.2 3.2 2 1 2 4 4 4 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 EGR34184.1 - 5.4e-25 87.4 0.5 1e-23 83.4 0.3 3.1 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_EZ PF13513.6 EGR34184.1 - 0.003 18.0 0.0 0.89 10.1 0.0 3.0 3 0 0 3 3 3 1 HEAT-like repeat RICTOR_N PF14664.6 EGR34185.1 - 2.3e-45 155.2 3.0 3.1e-45 154.8 1.8 1.8 1 1 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term DUF4459 PF14673.6 EGR34185.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) Tma16 PF11176.8 EGR34185.1 - 6.7 6.6 9.9 4.2 7.3 3.7 2.8 2 1 1 3 3 3 0 Translation machinery-associated protein 16 tRNA-synt_His PF13393.6 EGR34186.1 - 8.5e-39 133.6 0.0 1.6e-38 132.8 0.0 1.4 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EGR34186.1 - 1.4e-10 41.2 0.0 2.9e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 EGR34186.1 - 0.00014 21.4 0.1 0.00038 20.1 0.1 1.7 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 EGR34186.1 - 0.00022 20.4 0.0 0.0015 17.7 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 EGR34186.1 - 0.00061 19.8 0.0 0.0017 18.3 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2d PF01409.20 EGR34186.1 - 0.0035 16.9 0.0 0.0067 15.9 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) BTB PF00651.31 EGR34186.1 - 0.015 15.6 0.9 0.041 14.1 0.1 2.1 2 0 0 2 2 2 0 BTB/POZ domain AMP-binding PF00501.28 EGR34187.1 - 9.4e-82 274.8 0.0 1.3e-81 274.4 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGR34187.1 - 0.00015 22.7 0.0 0.00032 21.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UCH PF00443.29 EGR34188.1 - 5.5e-44 150.6 8.4 9.1e-44 149.9 8.4 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR34188.1 - 2.4e-12 47.1 14.3 5.1e-12 46.0 14.3 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EGR34188.1 - 1.3e-06 28.1 2.7 4.5e-06 26.3 0.1 2.7 2 0 0 2 2 2 1 Ubiquitin family TBK1_ULD PF18396.1 EGR34188.1 - 0.0017 18.2 0.1 0.006 16.5 0.1 1.9 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain TTL PF03133.15 EGR34189.1 - 9.4e-19 67.6 1.3 1.2e-18 67.3 1.3 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR34189.1 - 5.8e-06 25.7 0.2 7.4e-06 25.4 0.2 1.2 1 0 0 1 1 1 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR34189.1 - 0.012 14.8 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp Kinesin PF00225.23 EGR34190.1 - 9.3e-114 379.8 0.5 9.3e-114 379.8 0.5 2.2 2 1 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGR34190.1 - 7e-29 100.7 0.8 7e-29 100.7 0.8 2.9 2 1 1 3 3 3 1 Microtubule binding AAA_22 PF13401.6 EGR34190.1 - 0.12 12.7 0.0 0.12 12.7 0.0 3.2 2 1 0 2 2 2 0 AAA domain UTP25 PF06862.12 EGR34191.1 - 9.7e-45 153.2 17.0 1.2e-43 149.6 16.6 2.3 1 1 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 RGS PF00615.19 EGR34191.1 - 0.0088 16.3 2.2 0.0088 16.3 2.2 3.4 2 1 1 3 3 3 1 Regulator of G protein signaling domain DEAD PF00270.29 EGR34191.1 - 0.08 12.7 0.8 0.15 11.8 0.6 1.8 1 1 0 1 1 1 0 DEAD/DEAH box helicase LptE PF04390.12 EGR34191.1 - 0.13 13.0 2.1 0.33 11.7 2.1 1.7 1 0 0 1 1 1 0 Lipopolysaccharide-assembly DUF1616 PF07760.11 EGR34191.1 - 0.2 11.0 3.2 0.35 10.2 3.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) Peptidase_C54 PF03416.19 EGR34192.1 - 8.6e-64 215.6 0.4 1.6e-63 214.7 0.4 1.4 1 1 0 1 1 1 1 Peptidase family C54 PI3_PI4_kinase PF00454.27 EGR34193.1 - 2e-29 103.2 0.3 8.5e-22 78.2 0.3 3.7 2 2 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase Citrate_synt PF00285.21 EGR34195.1 - 2.2e-98 329.6 0.0 2.6e-98 329.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain EspA PF03433.13 EGR34195.1 - 0.18 11.7 0.2 0.7 9.7 0.0 2.0 2 0 0 2 2 2 0 EspA-like secreted protein DUF4407 PF14362.6 EGR34197.1 - 0.0094 15.3 9.8 0.016 14.6 9.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) NiFe-hyd_HybE PF11939.8 EGR34197.1 - 0.12 12.2 0.2 0.18 11.7 0.2 1.3 1 0 0 1 1 1 0 [NiFe]-hydrogenase assembly, chaperone, HybE Prominin PF05478.11 EGR34197.1 - 0.35 8.8 25.7 0.47 8.4 25.7 1.1 1 0 0 1 1 1 0 Prominin DUF4259 PF14078.6 EGR34197.1 - 0.75 10.5 9.2 0.98 10.2 8.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4259) HTH_54 PF18607.1 EGR34197.1 - 1.6 8.9 11.9 0.11 12.6 1.5 3.4 2 1 0 3 3 3 0 ParA helix turn helix domain Ribosomal_L6e PF01159.19 EGR34197.1 - 3.8 8.1 18.4 0.26 11.8 9.4 2.6 1 1 2 3 3 3 0 Ribosomal protein L6e Golgin_A5 PF09787.9 EGR34197.1 - 4 6.8 30.5 0.69 9.3 25.9 1.7 1 1 1 2 2 2 0 Golgin subfamily A member 5 LodA_N PF17990.1 EGR34197.1 - 5.3 6.9 7.8 3.2 7.6 5.8 1.6 1 1 1 2 2 2 0 L-Lysine epsilon oxidase N-terminal HALZ PF02183.18 EGR34198.1 - 3.2e-05 24.0 2.5 5.9e-05 23.2 2.5 1.4 1 0 0 1 1 1 1 Homeobox associated leucine zipper APG6_N PF17675.1 EGR34198.1 - 0.00016 22.2 2.9 0.00021 21.8 2.9 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region bZIP_1 PF00170.21 EGR34198.1 - 0.00022 21.3 3.3 0.00022 21.3 3.3 2.0 2 0 0 2 2 2 1 bZIP transcription factor ZapB PF06005.12 EGR34198.1 - 0.00038 20.8 3.4 0.00038 20.8 3.4 1.7 2 0 0 2 2 2 1 Cell division protein ZapB DivIC PF04977.15 EGR34198.1 - 0.0011 18.7 1.5 0.0011 18.7 1.5 1.7 2 0 0 2 2 2 1 Septum formation initiator Nnf1 PF03980.14 EGR34198.1 - 0.0061 16.9 0.8 0.027 14.8 0.8 1.9 1 1 0 1 1 1 1 Nnf1 Phage_GP20 PF06810.11 EGR34198.1 - 0.011 15.6 2.6 0.013 15.3 0.7 1.8 2 0 0 2 2 2 0 Phage minor structural protein GP20 Prp19 PF08606.11 EGR34198.1 - 0.012 15.6 0.9 0.012 15.6 0.9 1.7 2 0 0 2 2 2 0 Prp19/Pso4-like Cnn_1N PF07989.11 EGR34198.1 - 0.013 15.6 0.5 0.013 15.6 0.5 2.1 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 FliD_C PF07195.12 EGR34198.1 - 0.015 14.7 0.1 0.024 14.1 0.1 1.3 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus DUF2730 PF10805.8 EGR34198.1 - 0.023 14.8 0.6 0.032 14.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) ADIP PF11559.8 EGR34198.1 - 0.027 14.5 0.9 0.027 14.5 0.9 1.9 3 0 0 3 3 2 0 Afadin- and alpha -actinin-Binding Dak1_2 PF13684.6 EGR34198.1 - 0.032 13.3 0.3 0.057 12.5 0.3 1.6 1 1 0 1 1 1 0 Dihydroxyacetone kinase family FlaC_arch PF05377.11 EGR34198.1 - 0.032 14.6 1.3 0.032 14.6 1.3 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DivIVA PF05103.13 EGR34198.1 - 0.042 13.9 1.4 0.042 13.9 1.4 1.5 2 0 0 2 2 2 0 DivIVA protein Speriolin_N PF15058.6 EGR34198.1 - 0.044 13.9 0.2 0.15 12.2 0.3 1.7 2 0 0 2 2 2 0 Speriolin N terminus Herpes_BLRF2 PF05812.12 EGR34198.1 - 0.047 13.8 2.3 0.1 12.7 2.3 1.6 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein Rota_NSP3 PF01665.16 EGR34198.1 - 0.072 12.2 0.4 0.075 12.1 0.4 1.0 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 APC_N_CC PF16689.5 EGR34198.1 - 0.084 12.9 3.0 1.1 9.3 0.6 2.4 1 1 1 2 2 2 0 Coiled-coil N-terminus of APC, dimerisation domain V_ATPase_I PF01496.19 EGR34198.1 - 0.089 10.7 1.0 0.088 10.7 1.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Prominin PF05478.11 EGR34198.1 - 0.1 10.5 0.4 0.24 9.3 0.4 1.5 1 1 0 1 1 1 0 Prominin DUF2381 PF09544.10 EGR34198.1 - 0.12 11.9 0.3 0.17 11.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2381) YabA PF06156.13 EGR34198.1 - 0.94 10.2 4.0 0.43 11.2 1.3 1.8 1 1 1 2 2 2 0 Initiation control protein YabA LapA_dom PF06305.11 EGR34198.1 - 1 9.3 2.3 1.9 8.3 2.3 1.5 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain GrpE PF01025.19 EGR34198.1 - 2.2 7.9 7.6 13 5.5 7.6 1.9 1 1 0 1 1 1 0 GrpE bZIP_2 PF07716.15 EGR34198.1 - 2.7 8.2 9.8 0.09 12.9 3.8 1.7 2 0 0 2 2 2 0 Basic region leucine zipper DUF543 PF04418.12 EGR34199.1 - 0.0067 16.4 0.1 0.0078 16.2 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF543) HEAT PF02985.22 EGR34200.1 - 4.5e-25 85.6 0.1 0.028 14.6 0.0 9.9 10 0 0 10 10 10 5 HEAT repeat HEAT_2 PF13646.6 EGR34200.1 - 3.8e-16 59.2 0.0 0.0014 18.9 0.0 5.6 3 1 2 5 5 5 4 HEAT repeats Vac14_Fab1_bd PF12755.7 EGR34200.1 - 3e-07 30.9 16.1 0.36 11.5 0.8 5.8 3 1 3 6 6 6 5 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EGR34200.1 - 0.00011 21.9 11.6 0.057 13.0 0.4 4.5 2 1 2 4 4 4 3 CLASP N terminal IFRD PF05004.13 EGR34200.1 - 0.031 13.4 0.1 1.1 8.2 0.0 3.1 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) TAF6_C PF07571.13 EGR34200.1 - 0.04 14.2 1.3 1.3 9.4 0.1 3.8 2 2 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain HEAT_EZ PF13513.6 EGR34200.1 - 0.15 12.6 0.0 1.3e+02 3.2 0.0 4.6 5 1 1 6 6 6 0 HEAT-like repeat RP-C PF03428.13 EGR34200.1 - 0.21 11.2 0.5 24 4.5 0.1 2.4 2 0 0 2 2 2 0 Replication protein C N-terminal domain DsrD PF08679.11 EGR34200.1 - 1 9.7 4.7 2.1 8.7 0.1 3.5 3 1 1 4 4 4 0 Dissimilatory sulfite reductase D (DsrD) RNA_pol_Rpb1_5 PF04998.17 EGR34200.1 - 3.4 7.0 5.1 5.9 6.2 0.4 2.8 2 1 0 2 2 2 0 RNA polymerase Rpb1, domain 5 DUF3385 PF11865.8 EGR34200.1 - 4.9 7.0 19.4 0.25 11.2 0.9 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) FBPase PF00316.20 EGR34202.1 - 3.6e-13 49.4 0.0 8.5e-13 48.2 0.0 1.6 2 0 0 2 2 2 1 Fructose-1-6-bisphosphatase, N-terminal domain ERGIC_N PF13850.6 EGR34203.1 - 0.00013 22.3 2.6 0.00044 20.5 0.8 2.8 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Ras PF00071.22 EGR34204.1 - 5.6e-62 208.1 3.7 6.8e-62 207.8 3.7 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR34204.1 - 4.3e-35 120.5 1.0 7.6e-35 119.7 1.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR34204.1 - 1.8e-14 53.6 0.4 2.4e-14 53.2 0.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR34204.1 - 5e-06 26.6 0.8 7.8e-06 25.9 0.3 1.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGR34204.1 - 5.5e-05 22.7 0.2 8.1e-05 22.1 0.2 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EGR34204.1 - 0.00014 21.8 0.7 0.049 13.5 0.1 2.5 1 1 2 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 EGR34204.1 - 0.00017 21.0 1.2 0.00025 20.5 1.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGR34204.1 - 0.0011 18.5 0.3 0.003 17.1 0.3 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGR34204.1 - 0.0064 16.0 0.4 0.053 13.1 0.4 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.6 EGR34204.1 - 0.018 15.1 0.6 0.15 12.1 0.6 2.3 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGR34204.1 - 0.022 14.7 4.0 0.05 13.5 4.0 1.6 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea TniB PF05621.11 EGR34204.1 - 0.068 12.6 0.1 0.18 11.2 0.0 1.6 2 0 0 2 2 2 0 Bacterial TniB protein CENP-M PF11111.8 EGR34204.1 - 0.086 12.0 0.0 0.15 11.2 0.0 1.4 1 1 0 1 1 1 0 Centromere protein M (CENP-M) ERGIC_N PF13850.6 EGR34205.1 - 0.012 16.0 0.4 0.012 16.0 0.4 2.6 3 0 0 3 3 3 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Mem_trans PF03547.18 EGR34205.1 - 0.27 9.6 2.0 0.37 9.1 0.7 1.8 2 0 0 2 2 2 0 Membrane transport protein E1-E2_ATPase PF00122.20 EGR34206.1 - 4.3e-05 23.1 0.1 9.6e-05 22.0 0.1 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EGR34206.1 - 0.00075 19.8 0.0 0.046 14.0 0.0 2.4 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGR34206.1 - 0.16 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 Cation transport ATPase (P-type) DUF1687 PF07955.11 EGR34206.1 - 2.2 8.8 5.9 0.27 11.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1687) Profilin PF00235.19 EGR34207.1 - 1.6e-25 89.8 0.8 1.9e-25 89.6 0.8 1.0 1 0 0 1 1 1 1 Profilin LIFR_N PF18207.1 EGR34207.1 - 0.032 14.6 0.0 0.055 13.8 0.0 1.5 1 0 0 1 1 1 0 Leukemia inhibitory factor receptor N-terminal domain UCH PF00443.29 EGR34208.1 - 1.1e-43 149.6 10.1 1.1e-43 149.6 10.1 3.8 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR34208.1 - 4.4e-25 89.0 7.9 4.4e-25 89.0 7.9 3.8 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase EF-hand_7 PF13499.6 EGR34209.1 - 4e-17 62.4 1.1 1e-09 38.7 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR34209.1 - 2.1e-15 55.0 1.2 0.00037 19.8 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGR34209.1 - 1.2e-14 52.9 0.3 0.00011 21.8 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EGR34209.1 - 2.6e-10 39.3 4.9 0.0021 17.5 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EGR34209.1 - 3.4e-07 30.0 0.6 0.0096 15.8 0.0 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_10 PF14788.6 EGR34209.1 - 0.00061 19.6 0.2 0.094 12.6 0.0 3.0 3 0 0 3 3 3 1 EF hand Dockerin_1 PF00404.18 EGR34209.1 - 0.043 14.0 0.1 4.4 7.6 0.1 2.5 2 1 1 3 3 3 0 Dockerin type I domain PCMT PF01135.19 EGR34210.1 - 1.7e-36 126.0 0.0 2.3e-36 125.5 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EGR34210.1 - 6.2e-05 23.6 0.0 0.00014 22.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGR34210.1 - 0.00079 20.0 0.0 0.002 18.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 EGR34210.1 - 0.0011 19.9 0.0 0.0025 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGR34210.1 - 0.0018 17.7 0.1 0.0018 17.7 0.1 1.9 2 1 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.18 EGR34210.1 - 0.023 14.1 0.0 0.033 13.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGR34210.1 - 0.57 11.0 0.0 0.57 11.0 0.0 3.3 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_32 PF13679.6 EGR34210.1 - 1.4 8.9 0.0 1.4 8.9 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain UCH PF00443.29 EGR34211.1 - 3.6e-74 249.5 7.4 3.6e-74 249.5 7.4 2.9 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR34211.1 - 1.2e-18 67.8 9.6 1.2e-18 67.8 9.6 3.1 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf-B_box PF00643.24 EGR34213.1 - 0.00015 21.8 7.6 0.00015 21.8 7.6 4.1 4 0 0 4 4 4 2 B-box zinc finger zf-RING_5 PF14634.6 EGR34213.1 - 0.0065 16.4 7.3 0.0065 16.4 7.3 2.6 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGR34213.1 - 0.01 15.6 10.4 0.01 15.6 10.4 2.9 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGR34213.1 - 0.011 15.7 11.6 0.011 15.7 11.6 3.1 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Cystatin PF00031.21 EGR34215.1 - 0.001 19.3 0.0 0.0017 18.6 0.0 1.4 1 0 0 1 1 1 1 Cystatin domain PI3_PI4_kinase PF00454.27 EGR34216.1 - 2.9e-29 102.6 1.4 2.9e-25 89.5 1.4 2.2 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase DUF4135 PF13575.6 EGR34216.1 - 0.00023 20.6 0.0 0.00042 19.8 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4135) PAZ PF02170.22 EGR34216.1 - 0.05 13.4 1.9 0.13 12.1 1.9 1.6 1 0 0 1 1 1 0 PAZ domain Focal_AT PF03623.13 EGR34216.1 - 0.14 12.2 0.5 4 7.4 0.1 2.2 2 0 0 2 2 2 0 Focal adhesion targeting region Furin-like_2 PF15913.5 EGR34217.1 - 0.51 10.5 32.1 1.3 9.2 15.9 2.6 1 1 1 2 2 2 0 Furin-like repeat, cysteine-rich ABC_tran PF00005.27 EGR34219.1 - 5.5e-31 107.9 0.0 1.3e-30 106.7 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGR34219.1 - 2.5e-13 50.5 9.4 1.1e-10 41.8 0.0 3.4 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system MORN PF02493.20 EGR34219.1 - 2.3e-07 30.3 10.8 0.008 16.0 0.7 3.7 3 0 0 3 3 3 3 MORN repeat SMC_N PF02463.19 EGR34219.1 - 0.0012 18.3 0.2 0.22 10.9 0.0 2.4 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGR34219.1 - 0.009 16.5 0.4 0.009 16.5 0.4 3.6 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EGR34219.1 - 0.013 15.3 0.1 0.034 13.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.17 EGR34219.1 - 0.015 15.0 0.0 2.3 7.9 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGR34219.1 - 0.018 14.4 0.0 0.59 9.5 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI SbcCD_C PF13558.6 EGR34219.1 - 0.15 12.3 0.0 0.4 11.0 0.0 1.7 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit LRR_4 PF12799.7 EGR34220.1 - 9.6e-15 54.5 53.5 1.7e-06 28.3 5.4 6.7 5 2 1 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGR34220.1 - 3.9e-13 49.0 38.6 4.7e-05 23.1 8.0 6.0 3 2 2 5 5 5 5 Leucine rich repeat LRR_9 PF14580.6 EGR34220.1 - 3.1e-09 36.6 20.4 7.5e-07 28.8 9.3 2.8 1 1 2 3 3 3 3 Leucine-rich repeat LRR_6 PF13516.6 EGR34220.1 - 2.6e-08 33.3 33.0 0.16 12.1 0.0 9.0 7 1 1 8 8 8 6 Leucine Rich repeat DUF3179 PF11376.8 EGR34220.1 - 0.1 11.9 0.2 0.16 11.3 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3179) Pkinase PF00069.25 EGR34221.1 - 1.2e-09 38.0 2.6 1.2e-09 38.0 2.6 2.5 2 0 0 2 2 2 1 Protein kinase domain Furin-like_2 PF15913.5 EGR34222.1 - 3.8e-05 23.8 11.8 3.8e-05 23.8 11.8 7.6 1 1 6 7 7 7 3 Furin-like repeat, cysteine-rich VSP PF03302.13 EGR34222.1 - 0.0045 15.9 100.9 0.028 13.3 23.1 5.6 2 1 5 7 7 7 5 Giardia variant-specific surface protein DnaB_2 PF07261.11 EGR34222.1 - 0.046 13.5 0.4 1.3 8.8 0.2 2.5 2 0 0 2 2 2 0 Replication initiation and membrane attachment His_Phos_1 PF00300.22 EGR34223.1 - 5.4e-13 49.1 0.0 7.1e-07 29.1 0.0 3.2 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Peptidase_M24 PF00557.24 EGR34224.1 - 4.5e-47 160.4 0.0 5.3e-47 160.2 0.0 1.0 1 0 0 1 1 1 1 Metallopeptidase family M24 WBS_methylT PF12589.8 EGR34225.1 - 3.9e-14 53.2 7.6 6.7e-14 52.4 7.6 1.4 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_25 PF13649.6 EGR34225.1 - 1.9e-10 41.3 0.0 3.6e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGR34225.1 - 3.3e-10 40.5 0.0 5.9e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGR34225.1 - 1.3e-06 29.0 0.0 3.3e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 EGR34225.1 - 2.7e-06 27.3 1.2 0.0051 16.6 0.0 2.2 2 0 0 2 2 2 2 DNA methylase Methyltransf_31 PF13847.6 EGR34225.1 - 3.3e-06 27.0 0.0 5.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGR34225.1 - 9.2e-06 25.6 0.0 1.6e-05 24.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGR34225.1 - 0.00017 21.0 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EGR34225.1 - 0.00037 20.3 0.0 0.023 14.5 0.0 2.2 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MetW PF07021.12 EGR34225.1 - 0.0099 15.5 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW PrmA PF06325.13 EGR34225.1 - 0.012 15.0 0.1 0.027 13.9 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) AdoMet_MTase PF07757.13 EGR34225.1 - 0.021 15.2 0.0 0.055 13.8 0.0 1.7 2 0 0 2 2 1 0 Predicted AdoMet-dependent methyltransferase Methyltransf_32 PF13679.6 EGR34225.1 - 0.044 13.8 0.4 0.16 11.9 0.0 2.1 2 1 1 3 3 3 0 Methyltransferase domain MTS PF05175.14 EGR34225.1 - 0.079 12.5 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 EGR34225.1 - 0.13 11.5 0.0 0.24 10.7 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family CKS PF01111.19 EGR34226.1 - 7.6e-37 125.4 2.8 8.7e-37 125.2 2.8 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit DUF4338 PF14236.6 EGR34226.1 - 0.062 12.5 0.0 0.075 12.3 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4338) Pkinase PF00069.25 EGR34227.1 - 1.9e-63 214.3 0.4 2.6e-63 213.9 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34227.1 - 2e-38 132.2 0.2 5.2e-38 130.8 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EGR34227.1 - 2.9e-06 26.8 0.3 6.3e-06 25.7 0.3 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGR34227.1 - 0.00024 20.8 0.4 0.00057 19.5 0.4 1.6 1 1 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EGR34227.1 - 0.0013 18.7 0.0 0.01 15.7 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGR34227.1 - 0.0017 17.2 0.1 0.0091 14.8 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 EGR34227.1 - 0.074 12.7 3.3 0.29 10.7 0.1 2.5 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 FtsJ PF01728.19 EGR34228.1 - 2.8e-19 69.9 0.0 1e-18 68.0 0.0 2.0 2 0 0 2 2 2 1 FtsJ-like methyltransferase NapE PF06796.11 EGR34229.1 - 0.42 10.2 0.1 0.42 10.2 0.1 1.7 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE GerA PF03323.13 EGR34229.1 - 2.3 6.6 7.5 0.096 11.1 2.0 1.5 2 0 0 2 2 2 0 Bacillus/Clostridium GerA spore germination protein Pkinase PF00069.25 EGR34230.1 - 2e-58 197.9 0.9 2.9e-58 197.3 0.9 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34230.1 - 5.4e-34 117.6 0.1 9.3e-34 116.9 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR34230.1 - 5.3e-08 32.5 0.0 7.9e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR34230.1 - 0.00014 20.8 0.1 0.0003 19.7 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGR34230.1 - 0.008 15.6 0.1 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR34230.1 - 0.023 14.6 0.0 0.087 12.7 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family UvrB PF12344.8 EGR34230.1 - 0.19 11.6 3.7 0.9 9.4 1.0 2.5 2 0 0 2 2 2 0 Ultra-violet resistance protein B Kelch_3 PF13415.6 EGR34231.1 - 3.7e-13 49.4 0.1 2e-09 37.5 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_5 PF13854.6 EGR34231.1 - 8.2e-13 48.0 0.1 0.0003 20.7 0.0 3.8 3 0 0 3 3 3 3 Kelch motif Kelch_1 PF01344.25 EGR34231.1 - 2.7e-12 46.0 0.4 1.3e-05 24.7 0.1 3.4 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.6 EGR34231.1 - 8e-12 45.0 1.1 3.9e-05 23.6 0.1 4.3 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EGR34231.1 - 2.7e-09 37.0 0.8 9.4e-06 25.7 0.1 3.8 2 2 1 3 3 3 2 Kelch motif Kelch_2 PF07646.15 EGR34231.1 - 3e-06 27.0 2.9 0.15 12.1 0.0 4.2 4 1 0 4 4 4 2 Kelch motif DUF5074 PF16819.5 EGR34231.1 - 0.22 11.6 1.8 0.49 10.5 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5074) VID27 PF08553.10 EGR34232.1 - 4.6e-27 95.0 0.2 7.1e-27 94.4 0.2 1.2 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain WD40 PF00400.32 EGR34232.1 - 0.086 13.7 0.0 0.18 12.8 0.0 1.5 1 0 0 1 1 1 0 WD domain, G-beta repeat DNA_pol_E_B PF04042.16 EGR34233.1 - 1.1e-39 136.0 0.4 1.4e-39 135.6 0.4 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EGR34233.1 - 3.6e-12 46.5 0.1 8.6e-12 45.3 0.1 1.7 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain SpoU_methylase PF00588.19 EGR34234.1 - 5.4e-11 42.8 0.0 7.6e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family IncF PF17626.2 EGR34234.1 - 0.14 12.5 0.0 0.19 12.1 0.0 1.2 1 0 0 1 1 1 0 Inclusion membrane protein F MCM PF00493.23 EGR34237.1 - 3e-96 320.8 0.1 5.9e-96 319.9 0.1 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGR34237.1 - 4.1e-28 97.8 4.1 1e-27 96.5 4.1 1.7 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGR34237.1 - 7.6e-22 77.5 0.0 2.6e-21 75.9 0.0 2.0 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EGR34237.1 - 1.2e-08 34.6 0.1 2.2e-05 24.0 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGR34237.1 - 3.9e-07 30.2 0.1 3.5e-06 27.1 0.0 2.7 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) MCM_N PF14551.6 EGR34237.1 - 0.00055 20.5 2.5 0.0023 18.5 1.3 2.6 2 0 0 2 2 2 1 MCM N-terminal domain DUF494 PF04361.13 EGR34237.1 - 0.00091 19.1 1.0 0.0074 16.2 0.0 2.4 1 1 1 2 2 2 1 Protein of unknown function (DUF494) AAA_3 PF07726.11 EGR34237.1 - 0.0053 16.6 0.1 0.066 13.1 0.0 2.9 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) PIN_5 PF08745.11 EGR34237.1 - 0.017 14.5 0.0 0.017 14.5 0.0 2.5 3 0 0 3 3 3 0 PINc domain ribonuclease AAA_lid_2 PF17863.1 EGR34237.1 - 0.019 14.8 0.1 0.058 13.3 0.0 1.8 2 0 0 2 2 2 0 AAA lid domain AAA_16 PF13191.6 EGR34237.1 - 0.15 12.4 0.9 3.7 7.9 0.1 2.7 2 1 0 2 2 2 0 AAA ATPase domain Band_7 PF01145.25 EGR34238.1 - 2.9e-13 50.2 1.4 3.2e-13 50.1 0.3 1.6 1 1 1 2 2 2 1 SPFH domain / Band 7 family Glyco_hydro_2 PF00703.21 EGR34239.1 - 3.4e-08 34.1 0.0 7.1e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 2 Ig_mannosidase PF17753.1 EGR34239.1 - 0.015 15.0 0.0 0.039 13.7 0.0 1.7 1 0 0 1 1 1 0 Ig-fold domain EF-hand_7 PF13499.6 EGR34240.1 - 8.6e-16 58.2 12.0 5e-08 33.3 1.6 3.3 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR34240.1 - 9.5e-12 43.9 16.8 0.00055 19.7 0.2 5.2 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 EGR34240.1 - 1.1e-08 34.0 18.0 0.0075 15.7 1.0 5.0 6 0 0 6 6 6 3 EF hand EF-hand_8 PF13833.6 EGR34240.1 - 5.3e-05 23.0 8.3 0.0047 16.7 1.4 3.6 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EGR34240.1 - 0.00067 19.0 16.0 0.019 14.4 0.4 4.3 4 0 0 4 4 4 3 EF hand Pkinase PF00069.25 EGR34241.1 - 1.1e-13 51.2 0.0 1.1e-13 51.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34241.1 - 1.9e-05 24.1 0.0 1.9e-05 24.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR34241.1 - 0.00028 20.3 0.0 0.00029 20.2 0.0 1.0 1 0 0 1 1 1 1 Kinase-like DUF4459 PF14673.6 EGR34241.1 - 0.069 13.1 0.1 0.081 12.9 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) PIGA PF08288.12 EGR34242.1 - 1.1e-41 141.3 0.6 2.8e-41 140.0 0.1 2.0 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 EGR34242.1 - 4.6e-27 95.1 0.0 8.3e-27 94.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EGR34242.1 - 6.1e-24 84.5 0.0 1e-23 83.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGR34242.1 - 7.6e-21 74.9 0.0 1.2e-20 74.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGR34242.1 - 1.1e-08 35.7 0.0 1.6e-08 35.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EGR34242.1 - 0.00088 19.3 1.3 0.0066 16.5 0.2 2.6 2 1 1 3 3 3 1 Glycosyl transferase 4-like Tox-MPTase4 PF15640.6 EGR34242.1 - 0.046 13.6 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Metallopeptidase toxin 4 DUF2207 PF09972.9 EGR34245.1 - 0.001 17.9 0.0 0.0012 17.7 0.0 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Adeno_E3_CR2 PF02439.15 EGR34245.1 - 0.026 14.3 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Vpu PF00558.19 EGR34245.1 - 0.086 12.6 0.3 0.54 10.1 0.1 2.0 2 0 0 2 2 2 0 Vpu protein Mid2 PF04478.12 EGR34245.1 - 1.4 8.8 4.4 1.3 8.8 3.3 1.5 1 1 0 1 1 1 0 Mid2 like cell wall stress sensor Acyl-CoA_dh_1 PF00441.24 EGR34247.1 - 1.6e-40 138.8 0.0 2.2e-40 138.3 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGR34247.1 - 1.7e-34 118.9 0.0 3.3e-34 117.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGR34247.1 - 1.2e-26 92.7 0.1 2.5e-26 91.7 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGR34247.1 - 3.6e-11 43.5 0.0 5.3e-11 42.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 EGR34247.1 - 0.074 13.6 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal HpaB_N PF11794.8 EGR34247.1 - 0.12 12.0 0.0 0.45 10.1 0.0 1.9 1 1 0 1 1 1 0 4-hydroxyphenylacetate 3-hydroxylase N terminal PP2C PF00481.21 EGR34248.1 - 2.2e-47 161.9 0.0 6.8e-47 160.3 0.0 1.8 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGR34248.1 - 0.019 14.6 0.0 0.082 12.5 0.0 2.2 1 1 0 1 1 1 0 Protein phosphatase 2C B56 PF01603.20 EGR34249.1 - 7.1e-128 427.1 12.7 8.9e-128 426.8 12.7 1.0 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) CRAL_TRIO PF00650.20 EGR34251.1 - 1.1e-29 103.3 0.3 1.8e-29 102.5 0.3 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CPSase_L_D3 PF02787.19 EGR34251.1 - 0.036 14.4 0.1 0.081 13.3 0.1 1.6 1 0 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Pkinase PF00069.25 EGR34252.1 - 1.5e-67 227.8 1.9 3.2e-67 226.7 1.9 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34252.1 - 3e-33 115.2 0.2 5.2e-33 114.4 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR34252.1 - 4.9e-07 29.3 0.8 2.2e-05 23.9 0.0 2.3 1 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR34252.1 - 1.3e-06 27.5 0.0 2.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGR34252.1 - 2.7e-06 27.5 0.0 1.5e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGR34252.1 - 5.7e-06 25.8 0.4 2.5e-05 23.8 0.0 2.2 1 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EGR34252.1 - 0.00011 21.9 3.9 0.012 15.3 0.1 2.6 1 1 1 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 ATPgrasp_ST PF14397.6 EGR34252.1 - 0.0073 15.6 0.1 0.016 14.5 0.1 1.5 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp GutM PF06923.11 EGR34254.1 - 0.13 12.4 4.3 0.18 11.9 4.3 1.2 1 0 0 1 1 1 0 Glucitol operon activator protein (GutM) bZIP_1 PF00170.21 EGR34255.1 - 0.0056 16.7 0.5 0.0056 16.7 0.5 2.4 2 1 0 2 2 2 1 bZIP transcription factor TSC22 PF01166.18 EGR34255.1 - 0.012 15.9 1.2 0.012 15.9 1.2 2.2 1 1 1 2 2 2 0 TSC-22/dip/bun family CEP209_CC5 PF16574.5 EGR34255.1 - 0.015 15.5 2.8 0.018 15.2 2.8 1.1 1 0 0 1 1 1 0 Coiled-coil region of centrosome protein CE290 MRF_C1 PF13887.6 EGR34255.1 - 0.042 13.0 1.2 0.051 12.7 0.0 1.7 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 DUF2205 PF10224.9 EGR34255.1 - 0.1 12.6 3.5 0.34 10.9 1.5 2.5 1 1 1 2 2 2 0 Short coiled-coil protein Osmo_CC PF08946.10 EGR34255.1 - 7.3 6.9 10.6 28 5.1 0.2 3.3 1 1 2 3 3 3 0 Osmosensory transporter coiled coil Pkinase PF00069.25 EGR34257.1 - 1.9e-16 60.2 0.1 2.1e-16 60.1 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGR34257.1 - 9.6e-06 24.6 0.0 1.1e-05 24.4 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 EGR34257.1 - 8.4e-05 22.0 0.0 8.8e-05 21.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR34257.1 - 0.00033 20.1 0.1 0.00042 19.7 0.1 1.1 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR34257.1 - 0.0007 19.6 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family CLTH PF10607.9 EGR34258.1 - 1.3e-18 67.3 17.9 1.3e-18 67.3 17.9 2.6 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain CSTF1_dimer PF16699.5 EGR34258.1 - 0.00059 19.6 0.1 0.0018 18.0 0.1 1.8 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain Pkinase PF00069.25 EGR34261.1 - 1.5e-50 172.0 2.3 1.7e-50 171.8 2.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34261.1 - 1.9e-26 92.9 0.1 2.3e-26 92.6 0.1 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR34261.1 - 0.00013 22.0 0.0 0.00026 21.0 0.0 1.5 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR34261.1 - 0.00025 20.5 0.1 0.00038 19.9 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR34261.1 - 0.00055 18.8 0.1 0.0011 17.8 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGR34261.1 - 0.0013 18.1 0.0 0.037 13.4 0.0 2.1 2 0 0 2 2 2 1 Kinase-like EcKinase PF02958.20 EGR34261.1 - 0.018 14.4 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Ecdysteroid kinase YrbL-PhoP_reg PF10707.9 EGR34261.1 - 0.032 13.7 1.9 0.061 12.8 1.9 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL ParcG PF10274.9 EGR34262.1 - 2.9e-79 265.4 0.1 3.6e-79 265.1 0.1 1.1 1 0 0 1 1 1 1 Parkin co-regulated protein DCB PF16213.5 EGR34262.1 - 0.058 13.1 0.1 0.1 12.3 0.1 1.4 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 Cyt-b5 PF00173.28 EGR34263.1 - 1.4e-05 25.2 0.0 2.2e-05 24.5 0.0 1.7 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF2854 PF11016.8 EGR34263.1 - 0.049 13.5 0.0 0.073 13.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2854) Herpes_UL1 PF05259.11 EGR34263.1 - 0.062 13.4 0.1 0.19 11.8 0.0 1.9 1 1 1 2 2 2 0 Herpesvirus glycoprotein L Peptidase_M20 PF01546.28 EGR34265.1 - 2.9e-15 56.5 0.0 4.2e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGR34265.1 - 1.4e-09 37.8 0.0 2.8e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M14 PF00246.24 EGR34266.1 - 6.2e-39 134.5 0.4 7.6e-39 134.2 0.4 1.0 1 0 0 1 1 1 1 Zinc carboxypeptidase SIMPL PF04402.14 EGR34268.1 - 3e-13 50.7 0.7 3.6e-13 50.4 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF541) Aldo_ket_red PF00248.21 EGR34268.1 - 0.023 13.9 0.1 0.024 13.9 0.1 1.1 1 0 0 1 1 1 0 Aldo/keto reductase family DUF442 PF04273.13 EGR34268.1 - 0.06 13.4 0.0 0.071 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Lant_dehydr_C PF14028.6 EGR34269.1 - 0.0043 16.6 0.4 0.0067 16.0 0.4 1.2 1 0 0 1 1 1 1 Lantibiotic biosynthesis dehydratase C-term PAS PF00989.25 EGR34269.1 - 0.02 14.9 0.6 0.98 9.4 0.0 2.8 2 0 0 2 2 2 0 PAS fold ArgoMid PF16487.5 EGR34269.1 - 0.076 13.3 1.1 0.73 10.1 1.1 2.8 1 0 0 1 1 1 0 Mid domain of argonaute PAS_9 PF13426.7 EGR34269.1 - 0.079 13.2 4.4 0.081 13.2 0.0 3.4 3 1 0 3 3 3 0 PAS domain Blt1 PF12754.7 EGR34269.1 - 3.5 7.9 6.1 23 5.3 6.1 2.6 2 1 0 2 2 2 0 Blt1 N-terminal domain UCH PF00443.29 EGR34270.1 - 1.3e-52 178.9 12.2 1.3e-52 178.9 12.2 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR34270.1 - 9.6e-22 78.0 16.8 2.1e-21 76.8 16.8 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-FPG_IleRS PF06827.14 EGR34270.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.8 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS zf-4CXXC_R1 PF10497.9 EGR34270.1 - 0.12 12.6 0.6 0.32 11.2 0.6 1.7 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Pkinase PF00069.25 EGR34273.1 - 5.6e-62 209.5 1.9 7.6e-62 209.1 1.9 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34273.1 - 8.5e-41 139.9 0.1 1.4e-40 139.2 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR34273.1 - 3.9e-08 32.9 0.5 3.9e-08 32.9 0.5 2.0 2 1 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR34273.1 - 0.0011 17.9 0.0 0.0019 17.0 0.0 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR34273.1 - 0.036 13.4 0.1 0.055 12.8 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGR34273.1 - 0.2 11.3 3.3 7.9 6.0 0.1 2.7 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Ank_2 PF12796.7 EGR34274.1 - 1.5e-17 63.9 0.4 3e-08 34.1 0.0 3.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGR34274.1 - 2.4e-10 40.5 0.0 0.00011 22.4 0.0 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGR34274.1 - 1.1e-07 32.3 0.0 0.0011 19.5 0.0 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) FYVE PF01363.21 EGR34274.1 - 9.9e-05 22.4 5.0 0.00029 20.9 5.0 1.8 1 0 0 1 1 1 1 FYVE zinc finger Ank_3 PF13606.6 EGR34274.1 - 0.00092 19.5 0.0 4.3 8.2 0.0 4.1 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EGR34274.1 - 0.0083 16.5 0.0 2.1 8.9 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Pkinase PF00069.25 EGR34275.1 - 9e-64 215.4 5.1 1.4e-63 214.8 5.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34275.1 - 8.1e-41 140.0 1.5 1.2e-40 139.5 1.5 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR34275.1 - 1.6e-06 27.7 1.0 8.5e-05 22.0 0.6 2.6 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EGR34275.1 - 2.9e-05 24.1 0.0 7e-05 22.9 0.0 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR34275.1 - 0.00014 21.2 0.5 0.00027 20.4 0.5 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR34275.1 - 0.0017 17.2 0.3 0.011 14.5 0.1 2.1 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 EGR34275.1 - 0.0048 16.5 0.7 0.01 15.4 0.7 1.5 1 0 0 1 1 1 1 RIO1 family LLGL PF08366.13 EGR34275.1 - 0.008 16.5 0.0 0.023 15.0 0.0 1.9 1 0 0 1 1 1 1 LLGL2 DUF2711 PF10924.8 EGR34275.1 - 0.023 14.3 0.3 0.056 13.0 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2711) Pkinase PF00069.25 EGR34276.1 - 1.2e-26 93.7 0.1 1.9e-26 93.0 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34276.1 - 2.1e-13 50.2 0.0 2.9e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR34276.1 - 1.3e-06 27.5 0.0 2.4e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR34276.1 - 0.005 16.2 0.0 0.0089 15.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR34276.1 - 0.0079 16.1 0.0 0.063 13.2 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family NAC PF01849.18 EGR34277.1 - 7e-21 74.0 0.4 1.4e-20 73.0 0.4 1.5 1 0 0 1 1 1 1 NAC domain Trm112p PF03966.16 EGR34278.1 - 1.1e-15 57.9 1.5 8.2e-15 55.1 1.5 1.9 1 1 0 1 1 1 1 Trm112p-like protein HD PF01966.22 EGR34278.1 - 0.062 13.5 0.0 0.071 13.3 0.0 1.1 1 0 0 1 1 1 0 HD domain Antistasin PF02822.14 EGR34280.1 - 0.0012 19.4 12.7 0.59 10.8 0.1 6.3 6 0 0 6 6 6 2 Antistasin family Ephrin_rec_like PF07699.13 EGR34280.1 - 0.85 9.4 49.3 0.089 12.6 4.0 7.6 3 2 4 7 7 7 0 Putative ephrin-receptor like Mito_carr PF00153.27 EGR34281.1 - 3.8e-25 87.6 5.9 2.3e-12 46.7 0.2 2.6 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF2656 PF10847.8 EGR34281.1 - 0.13 12.4 0.7 0.24 11.5 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) RRM_2 PF04059.12 EGR34282.1 - 2e-35 120.9 2.8 3.5e-35 120.1 2.8 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 EGR34282.1 - 0.015 15.1 0.4 0.031 14.1 0.4 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 EGR34282.1 - 0.04 14.1 3.7 0.041 14.1 2.5 1.7 1 1 0 1 1 1 0 BRCA1-associated protein 2 Pkinase PF00069.25 EGR34283.1 - 1.9e-45 155.3 0.8 1.5e-25 90.1 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34283.1 - 9.3e-13 48.0 0.1 3.4e-07 29.8 0.2 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Thiolase_N PF00108.23 EGR34286.1 - 6.2e-83 278.1 0.0 1e-82 277.5 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGR34286.1 - 1.5e-41 140.9 0.5 2.7e-41 140.1 0.5 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGR34286.1 - 0.00016 21.3 0.0 0.00035 20.2 0.0 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain DUF3472 PF11958.8 EGR34288.1 - 1.6e-66 224.1 0.3 2.3e-66 223.5 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3472) DUF5077 PF16871.5 EGR34288.1 - 9.6e-37 126.7 5.2 7.3e-33 114.1 0.6 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF5077) Phage_TAC_10 PF10963.8 EGR34288.1 - 0.14 12.4 0.1 0.3 11.3 0.1 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone Zip PF02535.22 EGR34289.1 - 2.7e-37 128.8 11.3 4.2e-35 121.5 11.3 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter DUF3169 PF11368.8 EGR34289.1 - 0.009 15.6 4.6 0.11 12.0 0.0 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF3169) Thiolase_N PF00108.23 EGR34290.1 - 1.3e-83 280.4 0.0 2e-83 279.7 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGR34290.1 - 1e-29 102.7 0.0 2.1e-29 101.7 0.0 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGR34290.1 - 0.00016 21.3 0.0 0.00037 20.2 0.0 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain A_deaminase PF00962.22 EGR34291.1 - 2.1e-10 40.5 0.0 2.1e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 Adenosine/AMP deaminase HABP4_PAI-RBP1 PF04774.15 EGR34292.1 - 0.00021 22.1 8.7 0.00021 22.1 8.7 4.8 2 2 0 3 3 3 1 Hyaluronan / mRNA binding family U3_snoRNA_assoc PF08297.11 EGR34292.1 - 0.09 13.5 0.8 0.09 13.5 0.8 4.5 3 1 0 3 3 3 0 U3 snoRNA associated FAD_binding_3 PF01494.19 EGR34294.1 - 7e-37 127.5 0.0 4.7e-23 82.0 0.0 2.0 1 1 1 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 EGR34294.1 - 7.5e-06 25.4 0.4 0.00011 21.6 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGR34294.1 - 4.6e-05 22.8 0.0 0.00017 20.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase SE PF08491.10 EGR34294.1 - 7.5e-05 21.9 0.1 0.00011 21.4 0.1 1.3 1 0 0 1 1 1 1 Squalene epoxidase RE_SacI PF09566.10 EGR34294.1 - 0.0018 18.1 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 SacI restriction endonuclease Thi4 PF01946.17 EGR34294.1 - 0.0038 16.5 0.1 0.0063 15.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.24 EGR34294.1 - 0.0051 15.9 0.0 0.0073 15.4 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EGR34294.1 - 0.0075 15.4 0.0 0.61 9.1 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein HI0933_like PF03486.14 EGR34294.1 - 0.0086 14.8 0.1 0.043 12.5 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein RolB_RolC PF02027.17 EGR34294.1 - 0.01 15.5 0.3 0.022 14.4 0.3 1.5 1 0 0 1 1 1 0 RolB/RolC glucosidase family Pyr_redox PF00070.27 EGR34294.1 - 0.018 15.6 0.1 0.092 13.3 0.0 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGR34294.1 - 0.018 15.2 0.0 0.04 14.1 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF4871 PF16167.5 EGR34294.1 - 0.047 13.7 0.2 0.084 12.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4871) DAO PF01266.24 EGR34294.1 - 0.078 12.5 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase GIDA PF01134.22 EGR34294.1 - 0.093 11.8 0.7 0.19 10.8 0.0 1.9 3 0 0 3 3 3 0 Glucose inhibited division protein A Prefoldin_2 PF01920.20 EGR34295.1 - 5.4e-15 55.2 19.9 5.4e-15 55.2 19.9 2.2 2 1 0 2 2 2 1 Prefoldin subunit DMPK_coil PF08826.10 EGR34295.1 - 0.0023 18.0 23.6 0.038 14.1 7.5 2.5 2 1 0 2 2 2 2 DMPK coiled coil domain like Rx_N PF18052.1 EGR34295.1 - 9.8 6.5 13.2 4.2 7.7 3.6 2.4 1 1 1 2 2 2 0 Rx N-terminal domain RabGAP-TBC PF00566.18 EGR34296.1 - 1.6e-05 24.7 1.8 1.6e-05 24.7 1.8 2.3 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.25 EGR34297.1 - 6.7e-31 107.6 1.4 6.7e-31 107.6 1.4 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34297.1 - 7.2e-22 77.9 0.2 1.2e-21 77.2 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR34297.1 - 0.00041 19.7 0.0 0.00079 18.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR34297.1 - 0.00057 18.8 1.3 0.0015 17.4 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase MMtag PF10159.9 EGR34297.1 - 0.33 11.3 3.0 0.75 10.1 3.0 1.6 1 1 0 1 1 1 0 Multiple myeloma tumor-associated DUF812 PF05667.11 EGR34300.1 - 1.7e-44 152.7 49.5 1.7e-25 90.0 30.5 3.0 1 1 0 3 3 3 2 Protein of unknown function (DUF812) AATF-Che1 PF13339.6 EGR34300.1 - 0.024 15.3 4.5 0.024 15.3 4.5 2.8 2 1 1 3 3 3 0 Apoptosis antagonizing transcription factor WXG100 PF06013.12 EGR34300.1 - 0.14 12.4 4.3 1.3 9.3 0.3 3.7 2 2 1 3 3 3 0 Proteins of 100 residues with WXG DUF948 PF06103.11 EGR34300.1 - 3 8.2 10.8 37 4.7 0.0 4.1 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) MCPVI PF02993.14 EGR34300.1 - 7.1 6.4 12.6 1.5 8.6 4.4 2.5 2 1 0 2 2 2 0 Minor capsid protein VI DUF2209 PF09974.9 EGR34300.1 - 7.2 7.0 7.2 1.1 9.6 1.3 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2209) Meckelin PF09773.9 EGR34301.1 - 5.7e-95 319.1 37.3 1.2e-81 275.1 7.9 3.4 2 1 2 4 4 4 3 Meckelin (Transmembrane protein 67) Exo_endo_phos PF03372.23 EGR34302.1 - 0.0045 16.5 0.0 0.0069 15.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Mon1 PF03164.14 EGR34304.1 - 2e-11 43.6 0.1 2e-11 43.6 0.1 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Guanylate_cyc PF00211.20 EGR34305.1 - 1.5e-84 282.1 15.8 9.2e-47 159.0 2.1 2.6 3 0 0 3 3 3 2 Adenylate and Guanylate cyclase catalytic domain HrpB7 PF09486.10 EGR34307.1 - 0.0012 19.3 19.6 0.0049 17.3 0.8 3.1 2 1 1 3 3 3 2 Bacterial type III secretion protein (HrpB7) FAP206 PF12018.8 EGR34307.1 - 0.0015 18.1 29.0 0.24 10.9 5.5 3.8 1 1 2 3 3 3 2 Domain of unknown function DUF745 PF05335.13 EGR34307.1 - 0.0082 15.9 9.3 0.0082 15.9 9.3 3.9 2 1 3 5 5 5 1 Protein of unknown function (DUF745) FliJ PF02050.16 EGR34307.1 - 0.012 15.8 9.3 0.012 15.8 9.3 4.5 1 1 3 4 4 3 0 Flagellar FliJ protein DUF812 PF05667.11 EGR34307.1 - 0.05 12.5 40.4 2.5 6.9 17.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF812) DUF1664 PF07889.12 EGR34307.1 - 0.1 12.6 28.3 0.29 11.2 6.2 4.3 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 EGR34307.1 - 0.12 11.7 32.4 0.31 10.3 13.5 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3800 PF12686.7 EGR34307.1 - 0.72 10.5 3.0 28 5.4 3.0 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) MscS_porin PF12795.7 EGR34307.1 - 1.4 8.4 59.7 1 8.8 29.7 2.6 2 1 1 3 3 3 0 Mechanosensitive ion channel porin domain Laminin_II PF06009.12 EGR34307.1 - 1.9 8.5 36.0 0.31 11.1 9.9 3.4 1 1 2 3 3 3 0 Laminin Domain II DUF3584 PF12128.8 EGR34307.1 - 2.1 5.8 42.8 4 4.8 41.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) Exonuc_VII_L PF02601.15 EGR34307.1 - 2.5 7.6 36.7 0.43 10.1 15.3 2.3 1 1 0 2 2 2 0 Exonuclease VII, large subunit KxDL PF10241.9 EGR34307.1 - 2.7 8.3 36.2 1.4 9.3 1.8 4.4 2 2 2 4 4 4 0 Uncharacterized conserved protein AIP3 PF03915.13 EGR34307.1 - 2.9 6.9 35.4 0.078 12.1 13.8 2.4 1 1 1 2 2 2 0 Actin interacting protein 3 FUSC PF04632.12 EGR34307.1 - 3 6.2 10.3 7.9 4.9 5.3 2.3 1 1 1 2 2 2 0 Fusaric acid resistance protein family DUF16 PF01519.16 EGR34307.1 - 3.9 8.0 40.8 0.38 11.3 2.2 3.9 2 1 2 4 4 4 0 Protein of unknown function DUF16 ISG65-75 PF11727.8 EGR34307.1 - 4.9 6.3 20.2 0.027 13.7 5.0 3.0 2 1 0 3 3 3 0 Invariant surface glycoprotein ApoO PF09769.9 EGR34307.1 - 6.1 6.8 17.1 6.2 6.8 1.2 4.5 1 1 4 5 5 5 0 Apolipoprotein O LXG PF04740.12 EGR34307.1 - 7.2 6.3 37.5 0.35 10.6 8.9 4.2 2 1 1 4 4 4 0 LXG domain of WXG superfamily Pkinase PF00069.25 EGR34308.1 - 8.2e-65 218.8 0.7 8.2e-65 218.8 0.7 2.6 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34308.1 - 1e-32 113.5 0.2 2.4e-32 112.2 0.2 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase cNMP_binding PF00027.29 EGR34308.1 - 3.8e-25 87.8 0.1 1.2e-16 60.5 0.0 3.5 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Proteasome PF00227.26 EGR34308.1 - 0.0028 17.2 0.6 0.0078 15.7 0.6 1.7 1 0 0 1 1 1 1 Proteasome subunit Nop PF01798.18 EGR34308.1 - 0.013 15.0 0.5 0.013 15.0 0.5 2.3 2 0 0 2 2 2 0 snoRNA binding domain, fibrillarin DUF4347 PF14252.6 EGR34308.1 - 0.049 13.5 0.0 0.2 11.5 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4347) Exonuc_VII_S PF02609.16 EGR34308.1 - 0.094 12.8 1.9 0.31 11.1 1.9 2.0 1 0 0 1 1 1 0 Exonuclease VII small subunit DnaGprimase_HBD PF16730.5 EGR34310.1 - 0.041 14.0 9.2 0.14 12.2 2.5 2.8 2 1 1 3 3 3 0 DnaG-primase C-terminal, helicase-binding domain DUF5388 PF17363.2 EGR34310.1 - 0.076 13.2 0.4 0.3 11.3 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5388) Vac14_Fab1_bd PF12755.7 EGR34310.1 - 0.18 12.4 4.2 1.7 9.3 0.3 3.5 2 2 1 3 3 3 0 Vacuolar 14 Fab1-binding region Ins134_P3_kin PF05770.11 EGR34311.1 - 0.045 13.3 1.3 0.083 12.4 1.3 1.4 1 0 0 1 1 1 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain EF1_GNE PF00736.19 EGR34312.1 - 2.3e-23 82.2 3.4 2.3e-23 82.2 3.4 1.6 2 0 0 2 2 2 1 EF-1 guanine nucleotide exchange domain RadC PF04002.15 EGR34312.1 - 0.048 13.6 0.1 0.1 12.6 0.1 1.5 1 0 0 1 1 1 0 RadC-like JAB domain TRAP_alpha PF03896.16 EGR34312.1 - 0.093 11.9 3.6 0.14 11.3 3.6 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PBP1_TM PF14812.6 EGR34312.1 - 0.11 12.9 2.4 0.2 12.0 2.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Stm1_N PF09598.10 EGR34312.1 - 0.49 11.3 5.0 0.71 10.8 2.6 2.1 2 0 0 2 2 2 0 Stm1 Pkinase PF00069.25 EGR34313.1 - 6.1e-10 38.9 0.8 2.1e-09 37.2 0.8 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34313.1 - 1.5e-08 34.3 0.2 2.9e-08 33.3 0.2 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Histone PF00125.24 EGR34314.1 - 1.3e-47 161.4 2.4 1.5e-47 161.3 2.4 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 EGR34314.1 - 9.5e-05 22.7 0.1 0.00016 22.0 0.1 1.3 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 EGR34314.1 - 0.00035 21.2 0.5 0.0004 21.0 0.5 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EGR34314.1 - 0.00087 19.4 0.9 0.001 19.1 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 EGR34314.1 - 0.087 12.9 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DS PF01916.17 EGR34315.1 - 3.6e-96 321.8 0.1 4e-96 321.6 0.1 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase Ribosomal_S9 PF00380.19 EGR34316.1 - 6.1e-29 101.0 0.3 7e-29 100.8 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF2816 PF10992.8 EGR34317.1 - 6.4e-24 83.6 18.0 6.9e-24 83.5 16.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF2816) NPCC PF08058.11 EGR34318.1 - 5.7 7.0 10.5 6.6 6.8 10.4 1.3 1 1 0 1 1 1 0 Nuclear pore complex component Ank_2 PF12796.7 EGR34319.1 - 5e-23 81.5 10.4 2.6e-13 50.4 1.2 4.0 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGR34319.1 - 1.1e-20 73.7 6.0 8.3e-09 35.8 0.2 4.2 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGR34319.1 - 1.3e-19 70.0 0.0 7.6e-08 32.5 0.1 4.4 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EGR34319.1 - 2e-16 59.6 0.6 3.6e-05 24.0 0.3 4.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EGR34319.1 - 1.5e-14 52.7 2.3 0.00048 20.4 0.1 5.3 5 0 0 5 5 5 3 Ankyrin repeat DUF1803 PF08820.10 EGR34319.1 - 0.0051 16.8 8.1 0.027 14.5 7.8 2.4 1 1 1 2 2 2 1 Domain of unknown function (DUF1803) PIN7 PF18475.1 EGR34319.1 - 1.8 9.2 8.1 0.69 10.6 1.4 3.0 2 1 1 3 3 3 0 PIN domain Zip PF02535.22 EGR34320.1 - 4 6.6 7.4 3.8 6.6 7.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SMYLE_N PF18615.1 EGR34320.1 - 5.9 6.3 16.6 9 5.7 16.6 1.3 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain ThiF PF00899.21 EGR34322.1 - 1.6e-41 142.3 0.0 2.2e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 ThiF family Toprim PF01751.22 EGR34322.1 - 0.02 15.1 0.0 0.071 13.3 0.0 1.9 2 0 0 2 2 2 0 Toprim domain Shikimate_DH PF01488.20 EGR34322.1 - 0.092 12.8 0.0 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DOMON PF03351.17 EGR34323.1 - 4.2e-08 33.5 0.0 9.6e-08 32.3 0.0 1.7 1 0 0 1 1 1 1 DOMON domain NAD_binding_1 PF00175.21 EGR34323.1 - 0.00022 21.8 0.0 0.0006 20.4 0.0 1.7 1 1 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EGR34323.1 - 0.0012 19.0 0.0 1.2 9.2 0.0 2.3 1 1 0 2 2 2 2 Ferric reductase NAD binding domain Guanylate_cyc PF00211.20 EGR34324.1 - 8.6e-17 61.3 0.2 1.9e-16 60.2 0.2 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Pepsin-I3 PF06394.13 EGR34324.1 - 0.43 10.8 2.6 5.7 7.2 0.0 3.0 3 0 0 3 3 3 0 Pepsin inhibitor-3-like repeated domain DUF4320 PF14208.6 EGR34325.1 - 0.33 11.1 7.1 0.072 13.2 2.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4320) Cyt-b5 PF00173.28 EGR34326.1 - 1.3e-41 140.5 0.4 1.3e-19 70.1 0.1 2.1 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DUF2288 PF10052.9 EGR34326.1 - 0.045 13.8 2.0 2.2 8.4 0.3 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2288) Jiv90 PF14901.6 EGR34326.1 - 0.074 13.2 0.4 8.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone RPA_interact_M PF14767.6 EGR34327.1 - 0.046 14.3 0.3 0.27 11.8 0.2 2.4 2 0 0 2 2 2 0 Replication protein A interacting middle DUF4781 PF16013.5 EGR34327.1 - 0.38 9.5 6.1 2.6 6.8 0.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4781) Peptidase_M15_2 PF05951.13 EGR34327.1 - 0.53 9.9 2.8 3.4 7.3 0.5 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF882) Plk4_PB2 PF18409.1 EGR34327.1 - 5.8 7.7 11.7 0.098 13.3 1.5 3.3 4 1 0 4 4 4 0 Polo-like Kinase 4 Polo Box 2 PhoLip_ATPase_C PF16212.5 EGR34328.1 - 5.7e-39 134.4 31.9 2.6e-24 86.4 25.2 2.3 1 1 1 2 2 2 2 Phospholipid-translocating P-type ATPase C-terminal Hydrolase PF00702.26 EGR34328.1 - 1e-09 39.0 0.1 0.00025 21.4 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGR34328.1 - 0.00028 20.7 8.6 0.0068 16.2 0.4 2.5 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase C2-C2_1 PF11618.8 EGR34328.1 - 0.0016 18.5 0.4 0.04 14.0 0.0 2.2 2 0 0 2 2 2 1 First C2 domain of RPGR-interacting protein 1 PhoLip_ATPase_N PF16209.5 EGR34329.1 - 6.8e-19 67.3 3.7 6.8e-19 67.3 3.7 4.9 3 2 1 4 4 4 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGR34329.1 - 1.3e-09 38.0 0.1 5.4e-09 36.0 0.0 2.1 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGR34329.1 - 0.17 11.4 0.0 0.17 11.4 0.0 2.7 3 0 0 3 3 3 0 E1-E2 ATPase DUF4233 PF14017.6 EGR34329.1 - 7.6 6.9 8.9 12 6.3 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) Hexapep PF00132.24 EGR34330.1 - 0.0007 19.2 13.9 0.34 10.7 4.8 3.8 2 2 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EGR34330.1 - 0.17 10.8 4.1 0.4 9.6 0.7 2.0 1 1 1 2 2 2 0 L-fucokinase Hexapep_2 PF14602.6 EGR34330.1 - 2.1 8.2 12.5 1.4 8.7 5.4 3.2 2 1 2 4 4 4 0 Hexapeptide repeat of succinyl-transferase Dynein_light PF01221.18 EGR34331.1 - 8.3e-43 144.6 2.0 9.2e-43 144.5 2.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 LSM PF01423.22 EGR34332.1 - 5.2e-16 58.1 0.1 2.3e-15 56.0 0.1 2.2 1 0 0 1 1 1 1 LSM domain WD40 PF00400.32 EGR34333.1 - 2.1e-27 94.8 5.0 1e-05 26.1 0.0 5.7 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR34333.1 - 1.7e-18 66.7 3.7 2e-06 28.0 0.3 3.8 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGR34333.1 - 3.8e-07 30.2 3.6 0.00023 21.1 0.9 2.9 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGR34333.1 - 0.00098 18.5 0.0 0.39 10.0 0.0 2.7 1 1 1 3 3 3 2 WD40-like domain Ge1_WD40 PF16529.5 EGR34333.1 - 0.0066 15.5 0.3 0.044 12.8 0.0 2.1 1 1 1 2 2 2 1 WD40 region of Ge1, enhancer of mRNA-decapping protein MORN PF02493.20 EGR34334.1 - 1.2e-52 172.7 117.4 8.3e-07 28.5 2.0 14.5 15 0 0 15 15 15 13 MORN repeat Pkinase PF00069.25 EGR34335.1 - 6.9e-67 225.6 0.3 9.1e-67 225.2 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34335.1 - 5.7e-50 170.0 1.2 2e-49 168.2 0.1 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR34335.1 - 5.4e-08 32.5 0.0 1.4e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR34335.1 - 2.5e-06 26.5 0.0 3.2e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR34335.1 - 0.0087 15.4 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family MORN PF02493.20 EGR34336.1 - 2.9e-45 149.5 73.9 2.7e-08 33.2 2.3 10.4 10 0 0 10 10 10 9 MORN repeat DEAD PF00270.29 EGR34336.1 - 9.2e-38 129.7 0.1 1.9e-37 128.7 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGR34336.1 - 8.5e-30 103.4 3.0 5.9e-28 97.4 0.2 3.2 2 1 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGR34336.1 - 3.6e-09 36.8 1.6 1.5e-08 34.9 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 EGR34336.1 - 0.00027 20.6 9.2 0.0024 17.4 9.2 2.1 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 EGR34336.1 - 0.0015 18.9 0.0 0.0028 18.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Helicase_C_2 PF13307.6 EGR34336.1 - 1.1 9.4 4.6 0.49 10.5 0.1 2.5 2 1 0 3 3 3 0 Helicase C-terminal domain MORN PF02493.20 EGR34337.1 - 1.2e-23 81.5 58.7 5.2e-06 26.0 0.9 8.6 9 0 0 9 9 9 7 MORN repeat Peptidase_C2 PF00648.21 EGR34337.1 - 2.5e-15 56.3 0.2 2.5e-15 56.3 0.2 2.5 2 1 1 3 3 3 1 Calpain family cysteine protease Pkinase PF00069.25 EGR34339.1 - 8.1e-51 172.9 1.7 8.1e-51 172.9 1.7 2.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34339.1 - 5.4e-37 127.5 0.1 1.7e-36 125.8 0.1 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR34339.1 - 1.5e-06 27.3 0.1 5.1e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase CDT1 PF08839.11 EGR34340.1 - 1.6e-25 90.4 7.5 1.6e-25 90.4 7.5 3.9 3 2 0 3 3 3 1 DNA replication factor CDT1 like TonB_C PF03544.14 EGR34340.1 - 0.12 12.8 0.4 0.29 11.6 0.4 1.6 1 0 0 1 1 1 0 Gram-negative bacterial TonB protein C-terminal FokI_N PF02981.15 EGR34340.1 - 0.63 10.2 3.3 16 5.6 2.3 2.6 2 0 0 2 2 2 0 Restriction endonuclease FokI, recognition domain AAA_28 PF13521.6 EGR34341.1 - 1.3e-21 77.5 0.1 4.5e-21 75.8 0.0 1.9 2 0 0 2 2 2 1 AAA domain Thymidylate_kin PF02223.17 EGR34341.1 - 0.01 15.5 0.8 0.033 13.9 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase AAA_18 PF13238.6 EGR34341.1 - 0.045 14.3 0.6 0.2 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Laminin_G_3 PF13385.6 EGR34342.1 - 2e-06 28.1 1.4 2.7e-05 24.3 1.5 2.3 1 1 1 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Tox-HNH-HHH PF15637.6 EGR34342.1 - 0.11 12.7 0.1 0.57 10.4 0.0 2.2 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif DUF846 PF05832.12 EGR34343.1 - 3.4e-44 150.3 17.2 5.5e-44 149.6 17.2 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF2207 PF09972.9 EGR34343.1 - 0.00028 19.8 8.8 0.0055 15.5 0.2 2.0 1 1 1 2 2 2 2 Predicted membrane protein (DUF2207) ATP-synt_I PF03899.15 EGR34343.1 - 0.0013 19.0 0.9 0.0013 19.0 0.9 2.4 2 1 0 2 2 2 1 ATP synthase I chain Zip PF02535.22 EGR34343.1 - 0.076 12.2 0.5 0.14 11.3 0.0 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter Goodbye PF17109.5 EGR34343.1 - 0.084 13.3 0.8 0.26 11.8 0.7 1.8 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain FAM176 PF14851.6 EGR34343.1 - 0.68 9.6 4.4 0.93 9.1 3.2 1.8 2 0 0 2 2 2 0 FAM176 family START PF01852.19 EGR34344.1 - 1.4e-06 27.9 0.0 1.4e-06 27.9 0.0 1.1 1 0 0 1 1 1 1 START domain Methyltr_RsmB-F PF01189.17 EGR34345.1 - 5.7e-32 111.0 0.0 1.5e-31 109.6 0.0 1.7 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 EGR34345.1 - 1.8e-13 50.5 0.2 1.8e-13 50.5 0.2 2.4 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGR34345.1 - 1.3e-07 32.3 0.1 1.9e-06 28.5 0.0 2.6 1 1 2 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGR34345.1 - 1.4e-07 31.1 0.2 4.4e-07 29.5 0.0 1.8 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family DUF2431 PF10354.9 EGR34345.1 - 3.6e-05 24.1 0.4 3.6e-05 24.1 0.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF2431) MTS PF05175.14 EGR34345.1 - 0.00019 21.0 0.0 0.00053 19.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase small domain GCD14 PF08704.10 EGR34345.1 - 0.0002 21.2 0.2 0.00067 19.4 0.0 1.9 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_15 PF09445.10 EGR34345.1 - 0.0006 19.4 0.6 0.0006 19.4 0.6 2.5 2 1 0 2 2 1 1 RNA cap guanine-N2 methyltransferase PCMT PF01135.19 EGR34345.1 - 0.0011 18.8 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 EGR34345.1 - 0.0018 18.4 0.1 0.03 14.5 0.0 2.2 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_12 PF08242.12 EGR34345.1 - 0.0023 18.6 0.3 0.013 16.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltr_RsmF_N PF17125.5 EGR34345.1 - 0.0074 16.8 0.3 0.03 14.8 0.1 2.2 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF Methyltransf_24 PF13578.6 EGR34345.1 - 0.025 15.6 0.0 0.055 14.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CBP_BcsQ PF06564.12 EGR34345.1 - 0.05 13.1 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsQ PrmA PF06325.13 EGR34345.1 - 0.062 12.7 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CS PF04969.16 EGR34345.1 - 0.082 13.9 1.7 0.34 11.9 0.9 2.4 2 0 0 2 2 2 0 CS domain RecJ_OB PF17768.1 EGR34345.1 - 5.2 7.3 9.8 0.81 10.0 0.2 3.4 4 0 0 4 4 4 0 RecJ OB domain TTL PF03133.15 EGR34346.1 - 2.9e-31 108.7 11.5 3.4e-31 108.5 11.5 1.0 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR34346.1 - 3.5e-06 26.5 0.6 0.0005 19.4 0.0 2.2 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR34346.1 - 0.0039 16.5 0.0 0.006 15.9 0.0 1.4 1 0 0 1 1 1 1 Sugar-transfer associated ATP-grasp RimK PF08443.11 EGR34346.1 - 0.038 13.6 0.2 0.14 11.8 0.0 1.9 2 0 0 2 2 2 0 RimK-like ATP-grasp domain SYCP2_SLD PF18584.1 EGR34346.1 - 0.087 13.1 5.9 0.11 12.7 1.2 2.4 2 1 0 2 2 2 0 Synaptonemal complex 2 Spt16M-like domain RRN9 PF10680.9 EGR34346.1 - 0.21 11.9 0.4 0.46 10.8 0.4 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor Oxysterol_BP PF01237.18 EGR34348.1 - 2.6e-121 405.0 3.7 2.6e-121 405.0 3.7 1.9 2 1 0 2 2 2 1 Oxysterol-binding protein PH PF00169.29 EGR34348.1 - 1.7e-10 41.3 0.5 9.3e-10 39.0 0.3 2.5 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 EGR34348.1 - 1.3e-06 28.6 0.8 4.5e-06 26.8 0.1 2.3 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 EGR34348.1 - 0.18 12.3 11.6 0.42 11.0 1.5 4.7 4 2 1 5 5 5 0 Pleckstrin homology domain Surp PF01805.20 EGR34349.1 - 3.3e-33 113.4 11.0 5.6e-17 61.5 1.0 3.2 3 0 0 3 3 3 2 Surp module PRP21_like_P PF12230.8 EGR34349.1 - 1.1e-12 48.3 14.4 1.1e-12 48.3 14.4 2.3 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Archease PF01951.16 EGR34349.1 - 0.69 10.2 3.4 0.4 10.9 1.0 1.8 2 0 0 2 2 2 0 Archease protein family (MTH1598/TM1083) PRP21_like_P PF12230.8 EGR34350.1 - 5e-18 65.8 1.3 5e-18 65.8 1.3 2.0 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Rad60-SLD PF11976.8 EGR34351.1 - 9.3e-25 86.3 1.9 1.1e-24 86.0 1.9 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGR34351.1 - 1.4e-13 50.3 0.6 1.7e-13 50.1 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin family Gp_dh_N PF00044.24 EGR34351.1 - 0.029 14.7 0.0 0.036 14.4 0.0 1.3 1 1 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain PFK PF00365.20 EGR34352.1 - 1.5e-61 208.3 1.4 1.8e-61 208.0 1.4 1.1 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 EGR34352.1 - 0.00088 18.9 0.2 0.0032 17.1 0.1 2.0 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 EGR34352.1 - 0.0026 17.0 0.0 0.0054 16.0 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase HECT PF00632.25 EGR34353.1 - 1.6e-80 270.9 2.1 1.6e-80 270.9 2.1 6.1 3 2 0 4 4 4 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.25 EGR34354.1 - 5.1e-59 199.8 0.3 8.5e-59 199.1 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34354.1 - 4.8e-36 124.4 0.0 7.9e-36 123.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Response_reg PF00072.24 EGR34354.1 - 8.1e-21 74.3 0.4 2.4e-20 72.8 0.4 1.8 1 0 0 1 1 1 1 Response regulator receiver domain Kinase-like PF14531.6 EGR34354.1 - 5.1e-08 32.6 0.0 1.1e-07 31.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR34354.1 - 3.3e-06 26.1 1.4 2e-05 23.6 0.1 2.2 2 0 0 2 2 2 1 Fungal protein kinase DUF3405 PF11885.8 EGR34354.1 - 0.07 11.7 2.3 0.11 11.1 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) GDH_N PF12466.8 EGR34354.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 Glutamate dehydrogenase N terminal Maf1 PF09174.10 EGR34354.1 - 0.43 10.7 5.8 3.3 7.9 2.4 2.5 1 1 1 2 2 2 0 Maf1 regulator GRAM PF02893.20 EGR34355.1 - 0.025 14.5 0.1 0.099 12.5 0.0 2.1 3 0 0 3 3 3 0 GRAM domain Vps36_ESCRT-II PF11605.8 EGR34355.1 - 0.13 12.5 0.0 0.25 11.5 0.0 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 SNAP PF14938.6 EGR34356.1 - 7e-77 258.6 21.7 8.3e-77 258.4 21.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EGR34356.1 - 0.00099 19.4 10.8 0.068 13.5 0.4 3.9 2 1 3 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGR34356.1 - 0.032 14.3 0.3 0.032 14.3 0.3 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat MIT PF04212.18 EGR34356.1 - 0.046 13.8 20.0 0.43 10.7 1.4 4.8 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 EGR34356.1 - 0.05 13.6 10.5 11 6.3 0.0 5.3 4 1 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGR34356.1 - 0.11 12.4 17.5 0.17 11.8 0.1 5.1 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGR34356.1 - 0.18 12.5 12.0 12 6.8 0.1 5.3 5 1 1 6 6 6 0 Tetratricopeptide repeat Sel1 PF08238.12 EGR34356.1 - 0.86 10.4 6.8 8.2 7.3 0.3 3.8 3 1 0 3 3 3 0 Sel1 repeat TPR_8 PF13181.6 EGR34356.1 - 3.2 8.2 16.7 0.89 9.9 0.3 5.4 5 1 1 6 6 6 0 Tetratricopeptide repeat NSF PF02071.20 EGR34356.1 - 7.5 7.8 26.1 28 6.1 0.1 7.9 8 0 0 8 8 8 0 Aromatic-di-Alanine (AdAR) repeat Pkinase PF00069.25 EGR34357.1 - 5.1e-44 150.6 0.6 9.4e-44 149.8 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pro_isomerase PF00160.21 EGR34357.1 - 1.5e-30 106.6 3.3 8.6e-30 104.1 0.3 2.5 3 0 0 3 3 3 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pkinase_Tyr PF07714.17 EGR34357.1 - 2.6e-30 105.6 0.0 5.7e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR34357.1 - 3.2e-06 26.2 0.3 1.4e-05 24.1 0.0 2.0 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 EGR34357.1 - 0.0047 16.3 0.0 0.0091 15.3 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGR34357.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Nop16 PF09420.10 EGR34358.1 - 4.4e-07 30.1 3.7 5.5e-07 29.8 3.7 1.2 1 1 0 1 1 1 1 Ribosome biogenesis protein Nop16 PH_12 PF16457.5 EGR34358.1 - 0.00043 20.8 1.2 0.00054 20.5 1.2 1.1 1 0 0 1 1 1 1 Pleckstrin homology domain DUF4523 PF15023.6 EGR34358.1 - 0.022 14.6 0.8 0.026 14.3 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) CppA_C PF14507.6 EGR34358.1 - 0.15 12.8 2.9 1.9 9.2 0.2 2.1 1 1 1 2 2 2 0 CppA C-terminal Scm3 PF10384.9 EGR34358.1 - 0.25 11.1 6.4 8.7 6.2 0.1 3.1 3 0 0 3 3 3 0 Centromere protein Scm3 Ribosomal_L7Ae PF01248.26 EGR34359.1 - 1e-24 86.1 0.2 1.4e-24 85.6 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EGR34359.1 - 5.6e-05 22.9 0.0 8.8e-05 22.3 0.0 1.4 1 1 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 EGR34359.1 - 0.0023 18.0 0.2 0.0028 17.7 0.2 1.1 1 0 0 1 1 1 1 RNase P subunit Pop3 Inhibitor_I29 PF08246.12 EGR34360.1 - 6.5e-13 48.9 3.5 1.2e-12 48.1 3.5 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) SMC_N PF02463.19 EGR34361.1 - 2.3e-61 207.0 48.2 1.9e-38 132.1 4.6 5.9 2 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGR34361.1 - 2.6e-22 79.3 0.0 1.6e-21 76.8 0.0 2.5 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EGR34361.1 - 1.6e-07 32.0 41.7 1.6e-07 32.0 41.7 8.9 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.6 EGR34361.1 - 7.1e-05 22.8 34.1 0.0006 19.7 5.5 5.1 2 2 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGR34361.1 - 0.00048 20.0 63.2 0.00048 20.0 63.2 5.5 2 2 2 4 4 4 1 AAA ATPase domain AAA_29 PF13555.6 EGR34361.1 - 0.00054 19.6 0.0 0.0011 18.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain Occludin_ELL PF07303.13 EGR34361.1 - 0.011 16.5 1.7 0.011 16.5 1.7 11.3 4 2 7 12 12 12 0 Occludin homology domain Peptidase_C5 PF00770.18 EGR34361.1 - 0.084 12.5 0.4 0.24 11.0 0.4 1.7 1 0 0 1 1 1 0 Adenovirus endoprotease DUF4200 PF13863.6 EGR34362.1 - 3.8e-22 78.9 20.8 3.8e-22 78.9 20.8 4.0 3 2 0 3 3 3 1 Domain of unknown function (DUF4200) DUF3322 PF11795.8 EGR34362.1 - 0.011 15.8 0.4 0.038 14.0 0.2 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) CotJB PF12652.7 EGR34362.1 - 7.4 6.9 8.6 3.5 7.9 1.6 3.1 1 1 1 2 2 2 0 CotJB protein Myosin_head PF00063.21 EGR34364.1 - 2.7e-169 564.6 53.3 1.1e-167 559.3 53.3 2.9 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_N PF02736.19 EGR34364.1 - 0.0075 16.1 0.0 0.016 15.0 0.0 1.5 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 EGR34364.1 - 0.0087 16.3 0.0 0.051 13.8 0.0 2.4 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGR34364.1 - 0.027 13.8 0.0 0.075 12.3 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 EGR34364.1 - 0.032 14.6 0.0 0.11 12.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain RsgA_GTPase PF03193.16 EGR34364.1 - 0.048 13.6 2.1 0.096 12.6 0.1 2.7 2 0 0 2 2 2 0 RsgA GTPase RCC1 PF00415.18 EGR34365.1 - 1e-27 96.5 3.9 6.9e-10 39.4 0.1 6.2 6 0 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR34365.1 - 8.2e-14 51.0 8.9 0.00012 21.7 0.2 4.7 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat AvrE_T3Es PF11725.8 EGR34365.1 - 0.16 9.2 1.4 0.17 9.1 0.2 1.5 2 0 0 2 2 2 0 AvrE-family Type-III effector proteins (T3Es) CLIP PF12032.8 EGR34365.1 - 0.18 12.1 2.4 0.61 10.4 0.3 2.7 2 0 0 2 2 2 0 Regulatory CLIP domain of proteinases Prenyltransf PF01255.19 EGR34367.1 - 2.6e-65 220.1 3.2 3e-65 219.9 3.2 1.0 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Ras PF00071.22 EGR34368.1 - 2e-39 134.8 0.0 2.7e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR34368.1 - 9.8e-27 93.6 0.0 1.4e-26 93.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR34368.1 - 2.6e-15 56.3 0.0 3.5e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR34368.1 - 1.3e-05 25.3 0.0 5.3e-05 23.3 0.0 1.8 1 1 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGR34368.1 - 0.00012 21.5 0.1 0.0014 18.0 0.1 2.1 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region TniB PF05621.11 EGR34368.1 - 0.0058 16.1 0.0 0.0088 15.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein GTP_EFTU PF00009.27 EGR34368.1 - 0.016 14.7 0.0 0.11 12.1 0.0 2.2 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain WD40 PF00400.32 EGR34370.1 - 5.1e-09 36.6 0.0 0.12 13.2 0.1 6.4 6 0 0 6 6 6 2 WD domain, G-beta repeat HELP PF03451.14 EGR34370.1 - 0.0014 18.4 0.0 0.0036 17.1 0.0 1.6 1 0 0 1 1 1 1 HELP motif Histone PF00125.24 EGR34371.1 - 7.8e-51 171.9 2.8 8.6e-51 171.7 2.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 EGR34371.1 - 0.0002 21.9 2.2 0.00026 21.6 2.2 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EGR34371.1 - 0.00024 21.2 0.8 0.0003 20.9 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGR34371.1 - 0.0023 18.3 0.0 0.0035 17.7 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EGR34371.1 - 0.062 13.4 0.1 0.12 12.4 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit TMA7 PF09072.10 EGR34371.1 - 0.068 14.0 3.3 0.12 13.2 3.3 1.4 1 0 0 1 1 1 0 Translation machinery associated TMA7 Furin-like_2 PF15913.5 EGR34373.1 - 0.00018 21.6 20.0 0.00018 21.6 20.0 3.9 1 1 2 3 3 3 1 Furin-like repeat, cysteine-rich VSP PF03302.13 EGR34373.1 - 0.0046 15.9 23.4 0.0046 15.9 23.4 2.6 1 1 2 3 3 3 2 Giardia variant-specific surface protein DUF1356 PF07092.12 EGR34374.1 - 0.017 14.4 3.6 0.023 14.0 3.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1356) Syncollin PF15138.6 EGR34374.1 - 0.038 14.2 0.3 0.09 13.0 0.3 1.7 1 1 0 1 1 1 0 Syncollin AcetDehyd-dimer PF09290.11 EGR34374.1 - 0.16 12.1 0.3 0.28 11.4 0.3 1.4 1 0 0 1 1 1 0 Prokaryotic acetaldehyde dehydrogenase, dimerisation SpecificRecomb PF10136.9 EGR34374.1 - 0.27 9.5 3.1 0.32 9.3 3.1 1.1 1 0 0 1 1 1 0 Site-specific recombinase Gly_acyl_tr_C PF08444.10 EGR34374.1 - 0.31 11.3 4.2 0.74 10.1 4.2 1.6 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Rhodanese PF00581.20 EGR34375.1 - 8.2e-21 74.5 0.0 1.1e-10 42.0 0.0 2.5 2 0 0 2 2 2 2 Rhodanese-like domain Lactamase_B PF00753.27 EGR34375.1 - 5.8e-11 42.8 0.0 1.4e-10 41.5 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 EGR34375.1 - 0.0042 17.0 0.0 0.0086 16.0 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain DUF442 PF04273.13 EGR34375.1 - 0.13 12.3 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 Putative phosphatase (DUF442) Pkinase PF00069.25 EGR34376.1 - 2.4e-61 207.4 0.1 2.4e-61 207.4 0.1 1.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34376.1 - 2.9e-34 118.6 0.0 5e-34 117.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR34376.1 - 1.1e-05 24.9 0.0 0.00022 20.6 0.0 2.3 1 1 0 2 2 2 1 Kinase-like APH PF01636.23 EGR34376.1 - 0.0089 16.0 0.0 0.76 9.6 0.1 2.4 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGR34376.1 - 0.17 10.7 0.1 0.17 10.7 0.1 2.5 2 1 1 3 3 3 0 Fungal protein kinase MFS_1 PF07690.16 EGR34377.1 - 2.5e-13 49.7 31.6 2.4e-08 33.3 8.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Ras PF00071.22 EGR34378.1 - 2.3e-50 170.3 1.8 2.3e-50 170.3 1.8 3.1 3 1 1 4 4 4 1 Ras family Roc PF08477.13 EGR34378.1 - 1.2e-32 112.6 3.0 1.8e-32 112.1 0.7 2.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR34378.1 - 3.8e-17 62.3 1.3 3.8e-17 62.3 1.3 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR34378.1 - 5.1e-08 33.0 0.3 5.1e-08 33.0 0.3 2.8 3 1 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGR34378.1 - 0.0027 17.2 1.4 0.019 14.5 0.0 2.7 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_22 PF13401.6 EGR34378.1 - 0.043 14.1 0.2 0.29 11.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 EGR34378.1 - 0.13 11.7 11.9 0.62 9.6 10.3 2.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain IP_trans PF02121.18 EGR34379.1 - 0.0034 17.0 0.2 0.038 13.6 0.1 2.0 1 1 1 2 2 2 2 Phosphatidylinositol transfer protein Antimicrobial_7 PF08102.11 EGR34379.1 - 0.063 13.5 0.0 0.1 12.9 0.0 1.3 1 0 0 1 1 1 0 Scorpion antimicrobial peptide Peptidase_M8 PF01457.16 EGR34380.1 - 5.9e-16 58.2 10.2 5.6e-14 51.7 1.0 2.4 1 1 1 2 2 2 2 Leishmanolysin VSP PF03302.13 EGR34380.1 - 1.7e-05 23.9 15.8 1.7e-05 23.9 15.8 2.0 1 1 0 2 2 2 1 Giardia variant-specific surface protein Tobravirus_2B PF05271.11 EGR34380.1 - 0.092 12.7 0.8 0.22 11.4 0.5 1.7 1 1 0 1 1 1 0 Tobravirus 2B protein DUF167 PF02594.16 EGR34382.1 - 6.5e-22 77.4 0.2 1.1e-21 76.7 0.2 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 YfhO PF09586.10 EGR34382.1 - 3.1 5.9 8.4 2.9 6.0 8.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO NYD-SP28 PF14772.6 EGR34383.1 - 0.02 14.9 6.8 0.049 13.7 6.8 1.6 1 0 0 1 1 1 0 Sperm tail Psu PF07455.11 EGR34383.1 - 0.034 13.7 0.1 0.045 13.3 0.1 1.3 1 0 0 1 1 1 0 Phage polarity suppression protein (Psu) Hfx_Cass5 PF18287.1 EGR34383.1 - 0.057 13.6 0.1 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Integron Cassette Protein Hfx_Cass5 DUF4633 PF15464.6 EGR34383.1 - 0.096 12.8 5.4 0.29 11.3 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4633) DUF4404 PF14357.6 EGR34383.1 - 0.14 12.8 1.6 0.36 11.5 1.6 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4404) Merozoite_SPAM PF07133.11 EGR34383.1 - 0.15 12.0 18.5 0.7 9.9 1.3 2.4 1 1 1 2 2 2 0 Merozoite surface protein (SPAM) Exonuc_VII_L PF02601.15 EGR34383.1 - 1.2 8.6 10.1 1.5 8.3 10.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit L31 PF09784.9 EGR34383.1 - 3.6 8.1 12.7 0.044 14.2 5.0 1.8 2 1 0 2 2 2 0 Mitochondrial ribosomal protein L31 bVLRF1 PF18826.1 EGR34383.1 - 4.4 7.2 8.6 1.7 8.5 2.2 2.3 2 0 0 2 2 2 0 bacteroidetes VLRF1 release factor Arf PF00025.21 EGR34384.1 - 2.5e-70 235.5 0.2 3.6e-70 234.9 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGR34384.1 - 9e-14 51.3 0.6 2.8e-13 49.7 0.0 1.8 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EGR34384.1 - 1.7e-13 50.8 0.0 3.7e-13 49.7 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGR34384.1 - 1.1e-12 47.9 6.1 3.7e-09 36.2 0.0 3.1 1 1 1 3 3 3 2 G-protein alpha subunit Ras PF00071.22 EGR34384.1 - 5.5e-12 45.6 0.0 9.1e-12 44.9 0.0 1.4 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGR34384.1 - 5.5e-11 42.3 0.0 9.7e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGR34384.1 - 1.1e-08 35.2 0.0 2.2e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGR34384.1 - 0.00015 21.4 0.4 0.0091 15.6 0.0 2.9 1 1 2 3 3 3 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 EGR34384.1 - 0.018 15.6 0.8 0.054 14.0 0.1 2.2 2 1 0 2 2 2 0 AAA domain HSDR_N PF04313.14 EGR34384.1 - 0.018 15.0 0.7 0.018 15.0 0.7 2.0 2 1 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) DUF883 PF05957.13 EGR34384.1 - 0.021 15.4 0.2 0.16 12.6 0.2 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) MeaB PF03308.16 EGR34384.1 - 0.045 12.7 0.0 0.18 10.7 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB FliD_N PF02465.18 EGR34384.1 - 0.058 14.1 1.2 0.43 11.3 0.1 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Takusan PF04822.13 EGR34384.1 - 0.083 12.8 1.7 0.27 11.1 0.4 2.4 2 0 0 2 2 2 0 Takusan Dynamin_N PF00350.23 EGR34384.1 - 0.34 10.9 3.3 2.1 8.4 0.0 3.0 2 2 0 3 3 3 0 Dynamin family NYD-SP28 PF14772.6 EGR34385.1 - 3.6e-22 78.3 21.3 3.6e-22 78.3 21.3 7.5 6 2 1 7 7 7 1 Sperm tail NYD-SP28_assoc PF14775.6 EGR34385.1 - 6.6e-21 74.2 7.2 6.6e-21 74.2 7.2 5.5 4 2 2 6 6 6 1 Sperm tail C-terminal domain APG9 PF04109.16 EGR34386.1 - 0.0093 15.0 11.9 0.0099 14.9 11.9 1.0 1 0 0 1 1 1 1 Autophagy protein Apg9 Coatomer_WDAD PF04053.14 EGR34387.1 - 1.5e-95 320.9 22.9 1.5e-95 320.9 22.9 1.9 2 0 0 2 2 2 1 Coatomer WD associated region COPI_C PF06957.11 EGR34387.1 - 6.3e-71 239.3 2.9 1.2e-70 238.3 2.9 1.4 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.32 EGR34387.1 - 5.1e-41 137.9 15.4 1.1e-07 32.4 0.1 7.8 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR34387.1 - 1.1e-07 32.0 4.7 0.17 12.2 0.1 6.3 3 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain CPSF100_C PF13299.6 EGR34387.1 - 0.12 12.6 2.3 0.24 11.6 1.3 2.0 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SH3_13 PF18335.1 EGR34387.1 - 0.14 12.0 2.9 2.1 8.2 0.3 3.1 2 0 0 2 2 2 0 ATP-dependent RecD-like DNA helicase SH3 domain FYDLN_acid PF09538.10 EGR34387.1 - 1.4 9.7 10.7 0.4 11.4 5.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Pkinase PF00069.25 EGR34388.1 - 1.5e-32 113.0 0.2 1.6e-32 112.9 0.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34388.1 - 4e-19 68.9 0.0 4.3e-19 68.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR34388.1 - 0.0012 17.7 0.0 0.0015 17.4 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGR34388.1 - 0.0089 15.4 0.0 0.012 15.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR34388.1 - 0.021 14.2 0.0 0.038 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Furin-like_2 PF15913.5 EGR34389.1 - 3.2e-20 72.3 141.9 1.1e-06 28.8 15.8 8.5 1 1 7 8 8 8 6 Furin-like repeat, cysteine-rich GF_recep_IV PF14843.6 EGR34389.1 - 0.006 16.4 28.9 0.006 16.4 28.9 6.4 1 1 4 6 6 6 3 Growth factor receptor domain IV DUF2459 PF09601.10 EGR34389.1 - 0.042 13.7 5.1 0.21 11.4 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2459) VSP PF03302.13 EGR34389.1 - 0.2 10.5 131.1 0.33 9.8 11.5 8.0 1 1 7 8 8 8 0 Giardia variant-specific surface protein Proteasome PF00227.26 EGR34390.1 - 1e-30 106.6 0.0 1.4e-30 106.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit SAM_3 PF18016.1 EGR34392.1 - 0.00035 20.3 1.5 0.0024 17.6 0.8 2.5 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) TP_methylase PF00590.20 EGR34393.1 - 6.8e-24 85.0 0.0 1.1e-23 84.3 0.0 1.3 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases TolA_bind_tri PF16331.5 EGR34394.1 - 0.029 14.5 0.6 0.029 14.5 0.6 1.9 2 0 0 2 2 2 0 TolA binding protein trimerisation GIT_CC PF16559.5 EGR34394.1 - 0.14 12.0 0.2 0.14 12.0 0.2 3.1 2 1 3 5 5 5 0 GIT coiled-coil Rho guanine nucleotide exchange factor Ribosomal_L3 PF00297.22 EGR34394.1 - 0.61 9.0 5.4 0.74 8.7 5.4 1.1 1 0 0 1 1 1 0 Ribosomal protein L3 Salp15 PF12115.8 EGR34394.1 - 1.4 9.3 9.4 1.3 9.4 4.8 2.1 1 1 1 2 2 2 0 Salivary protein of 15kDa inhibits CD4+ T cell activation DUF4275 PF14101.6 EGR34395.1 - 0.0032 17.6 7.6 0.0038 17.4 7.6 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4275) PDZ_6 PF17820.1 EGR34396.1 - 7.1e-06 25.8 0.0 1.1e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 EGR34396.1 - 1.2e-05 25.6 0.0 1.8e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 EGR34396.1 - 4e-05 23.9 0.2 6.2e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 PDZ domain GRASP55_65 PF04495.14 EGR34396.1 - 0.024 15.0 0.0 0.026 14.9 0.0 1.2 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Orai-1 PF07856.12 EGR34397.1 - 0.00067 19.4 3.8 0.0032 17.2 3.8 2.2 1 0 0 1 1 1 1 Mediator of CRAC channel activity OAD_gamma PF04277.13 EGR34397.1 - 0.046 14.3 2.0 0.25 12.0 0.1 3.3 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF4574 PF15141.6 EGR34397.1 - 1.6 8.7 0.0 1.6 8.7 0.0 3.3 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 AAA PF00004.29 EGR34399.1 - 2e-38 131.8 0.4 4.3e-38 130.7 0.1 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGR34399.1 - 1.8e-07 30.8 0.0 3.7e-07 29.8 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGR34399.1 - 7.9e-07 28.9 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGR34399.1 - 2.9e-05 24.3 0.1 9.6e-05 22.6 0.0 2.0 1 1 1 2 2 2 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EGR34399.1 - 5.2e-05 22.6 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain Vps4_C PF09336.10 EGR34399.1 - 0.0021 18.0 0.1 0.0078 16.2 0.1 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_24 PF13479.6 EGR34399.1 - 0.0022 17.8 0.1 0.06 13.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EGR34399.1 - 0.0049 16.9 0.5 0.016 15.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGR34399.1 - 0.0094 16.3 0.1 0.029 14.8 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 EGR34399.1 - 0.0096 16.3 0.0 0.038 14.4 0.0 2.2 1 1 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 EGR34399.1 - 0.014 15.4 0.3 0.22 11.5 0.2 2.7 2 1 0 2 2 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGR34399.1 - 0.031 13.7 0.0 0.082 12.3 0.0 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 EGR34399.1 - 0.037 14.6 0.3 0.14 12.7 0.1 2.2 2 1 0 2 2 1 0 AAA domain TniB PF05621.11 EGR34399.1 - 0.039 13.4 0.1 3.5 7.0 0.0 2.5 1 1 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 EGR34399.1 - 0.04 14.2 0.4 0.6 10.4 0.2 2.7 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGR34399.1 - 0.074 12.8 0.0 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_33 PF13671.6 EGR34399.1 - 0.13 12.4 0.0 0.32 11.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGR34399.1 - 0.18 11.4 0.0 5.5 6.5 0.0 2.3 1 1 0 2 2 2 0 AAA domain cNMP_binding PF00027.29 EGR34400.1 - 1.6e-22 79.3 0.0 4.7e-15 55.4 0.0 2.7 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Lactamase_B_2 PF12706.7 EGR34400.1 - 7.3e-05 22.4 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGR34400.1 - 0.0057 16.7 0.0 0.015 15.3 0.0 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily VIT1 PF01988.19 EGR34401.1 - 1.3 8.8 2.7 2.5 7.9 2.7 1.5 1 1 0 1 1 1 0 VIT family Tiam_CC_Ex PF18385.1 EGR34401.1 - 3.1 8.2 6.8 0.45 10.9 0.8 2.2 2 1 1 3 3 3 0 T-lymphoma invasion and metastasis CC-Ex domain adh_short PF00106.25 EGR34402.1 - 2.5e-34 118.5 0.0 3.5e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGR34402.1 - 2.1e-28 99.5 0.0 2.7e-28 99.1 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGR34402.1 - 4.1e-07 30.1 0.0 6.4e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 EGR34402.1 - 0.0013 18.1 0.2 0.014 14.7 0.1 2.2 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Eno-Rase_NADH_b PF12242.8 EGR34402.1 - 0.034 13.9 0.1 0.09 12.6 0.1 1.8 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Polysacc_synt_2 PF02719.15 EGR34402.1 - 0.055 12.6 0.1 0.11 11.6 0.1 1.5 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 EGR34402.1 - 0.087 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF5126 PF17166.4 EGR34402.1 - 0.13 12.1 0.0 2.1 8.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5126) TbpB_C PF17483.2 EGR34402.1 - 0.15 12.4 0.1 0.34 11.3 0.1 1.5 1 0 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B Pkinase PF00069.25 EGR34403.1 - 1.7e-53 181.7 6.9 2.4e-53 181.2 6.9 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34403.1 - 2e-32 112.5 1.6 2.8e-32 112.0 1.1 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR34403.1 - 1.5e-07 31.0 1.8 6e-07 29.1 0.1 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EGR34403.1 - 8e-07 28.6 1.2 9.7e-07 28.3 0.2 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGR34403.1 - 4.3e-06 26.5 1.5 4.3e-06 26.5 1.5 2.2 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EGR34403.1 - 1.9e-05 24.7 0.0 0.00083 19.3 0.0 2.5 2 1 1 3 3 3 1 Phosphotransferase enzyme family DUF4164 PF13747.6 EGR34403.1 - 0.0036 17.5 10.6 0.0092 16.2 3.5 2.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4164) TPX2 PF06886.11 EGR34403.1 - 1.7 9.0 4.7 4.5 7.6 0.6 2.9 2 0 0 2 2 2 0 Targeting protein for Xklp2 (TPX2) YvrJ PF12841.7 EGR34403.1 - 4.2 7.0 5.7 5 6.7 0.2 3.3 3 0 0 3 3 3 0 YvrJ protein family Styelin PF17562.2 EGR34404.1 - 0.017 15.4 0.2 0.043 14.2 0.2 1.7 1 0 0 1 1 1 0 Styelin PWWP PF00855.17 EGR34404.1 - 0.037 14.4 0.7 0.037 14.4 0.7 2.2 1 1 0 2 2 2 0 PWWP domain NlpE PF04170.12 EGR34404.1 - 6.2 7.9 14.9 5.7 8.0 5.8 3.2 2 1 1 3 3 3 0 NlpE N-terminal domain Pkinase PF00069.25 EGR34405.1 - 1.2e-70 237.9 0.3 1.2e-70 237.9 0.3 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34405.1 - 1.9e-40 138.8 0.0 1.9e-40 138.8 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase POLO_box PF00659.18 EGR34405.1 - 2.2e-32 111.0 8.3 3.2e-17 62.5 0.1 3.2 3 0 0 3 3 3 2 POLO box duplicated region Kinase-like PF14531.6 EGR34405.1 - 2.1e-09 37.1 9.9 6e-08 32.3 0.0 3.4 2 1 1 3 3 2 2 Kinase-like Ndufs5 PF10200.9 EGR34405.1 - 0.024 14.9 0.9 0.76 10.1 0.0 3.1 2 1 1 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa PepSY_TM PF03929.16 EGR34405.1 - 0.27 10.9 0.7 0.42 10.2 0.7 1.3 1 0 0 1 1 1 0 PepSY-associated TM region CLN3 PF02487.17 EGR34405.1 - 1.5 7.8 10.8 3.1 6.8 10.8 1.5 1 0 0 1 1 1 0 CLN3 protein Presenilin PF01080.17 EGR34405.1 - 1.6 7.4 15.2 2.8 6.6 15.2 1.3 1 0 0 1 1 1 0 Presenilin SMYLE_N PF18615.1 EGR34405.1 - 1.8 8.1 14.1 0.084 12.4 8.2 1.7 2 0 0 2 2 2 0 Short myomegalin-like EB1 binding proteins, N-terminal domain EPL1 PF10513.9 EGR34405.1 - 3.1 8.2 18.9 0.43 11.0 13.4 2.4 2 0 0 2 2 2 0 Enhancer of polycomb-like TFIIA PF03153.13 EGR34405.1 - 4.6 7.1 46.9 0.35 10.8 41.1 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit E1-E2_ATPase PF00122.20 EGR34406.1 - 2.9e-46 157.3 0.8 1.1e-43 148.9 0.0 2.6 2 0 0 2 2 2 2 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGR34406.1 - 1.5e-41 142.1 1.1 1.5e-41 142.1 1.1 3.0 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGR34406.1 - 3.3e-19 70.0 0.0 2.6e-16 60.5 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGR34406.1 - 2.5e-15 56.3 0.1 6.3e-15 55.0 0.1 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGR34406.1 - 2.5e-14 52.7 0.2 1.2e-13 50.5 0.1 2.2 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus DUF3040 PF11239.8 EGR34406.1 - 0.078 13.3 0.2 4.8 7.5 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF2207 PF09972.9 EGR34406.1 - 3.3 6.4 8.2 25 3.5 0.3 3.7 3 0 0 3 3 3 0 Predicted membrane protein (DUF2207) TPR_14 PF13428.6 EGR34407.1 - 2.6e-19 68.3 1.3 0.013 16.2 0.0 10.7 6 4 5 12 12 12 3 Tetratricopeptide repeat HAT PF02184.16 EGR34407.1 - 1.8e-17 63.0 43.2 0.00087 19.2 0.5 11.5 11 0 0 11 11 11 6 HAT (Half-A-TPR) repeat Suf PF05843.14 EGR34407.1 - 7.6e-14 52.4 56.2 5.9e-05 23.2 9.6 6.7 2 2 3 5 5 5 5 Suppressor of forked protein (Suf) TPR_19 PF14559.6 EGR34407.1 - 2e-13 50.6 0.1 0.00014 22.3 0.0 6.9 6 2 1 8 8 8 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGR34407.1 - 8.7e-11 41.4 10.9 0.6 10.6 0.1 7.2 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGR34407.1 - 0.0038 17.8 0.0 17 6.2 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGR34407.1 - 0.0039 17.7 12.7 1.1e+02 3.8 0.0 9.0 10 1 0 10 10 9 0 Tetratricopeptide repeat BSD PF03909.17 EGR34407.1 - 0.0098 15.9 9.5 1.1 9.3 1.1 4.6 3 1 1 4 4 4 2 BSD domain U3_assoc_6 PF08640.11 EGR34407.1 - 0.018 15.1 2.7 0.018 15.1 2.7 8.7 5 4 3 9 9 9 0 U3 small nucleolar RNA-associated protein 6 TPR_12 PF13424.6 EGR34407.1 - 0.033 14.5 5.7 37 4.7 0.1 6.0 6 2 0 6 6 6 0 Tetratricopeptide repeat SF3A3 PF16837.5 EGR34407.1 - 0.2 12.2 0.1 0.2 12.2 0.1 6.3 4 1 2 6 6 5 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 TPR_7 PF13176.6 EGR34407.1 - 1.7 8.8 8.8 9 6.6 0.1 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat VSP PF03302.13 EGR34409.1 - 1.1e-20 73.9 178.0 2.8e-06 26.4 40.5 6.1 1 1 4 5 5 5 5 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EGR34409.1 - 8.2 6.6 183.3 0.12 12.6 14.8 10.1 1 1 10 11 11 11 0 Furin-like repeat, cysteine-rich Topoisom_bac PF01131.20 EGR34411.1 - 2.7e-102 342.9 0.0 4.9e-102 342.0 0.0 1.4 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EGR34411.1 - 1.1e-18 67.3 0.0 2.6e-18 66.1 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 EGR34411.1 - 0.064 13.7 0.1 0.21 12.1 0.1 1.9 1 0 0 1 1 1 0 Toprim-like FYVE_2 PF02318.16 EGR34411.1 - 0.18 12.0 10.1 0.19 11.9 4.3 2.9 2 0 0 2 2 2 0 FYVE-type zinc finger zf-FPG_IleRS PF06827.14 EGR34411.1 - 1.1 9.2 5.4 0.83 9.6 0.8 2.6 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS DUF2318 PF10080.9 EGR34411.1 - 3.4 7.9 9.9 12 6.1 4.2 3.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Ribosomal_S27e PF01667.17 EGR34411.1 - 5.8 6.7 15.5 0.11 12.3 2.0 2.6 2 0 0 2 2 2 0 Ribosomal protein S27 TAP42 PF04177.12 EGR34412.1 - 2.8e-63 214.0 18.4 3.4e-63 213.7 18.4 1.0 1 0 0 1 1 1 1 TAP42-like family CwfJ_C_2 PF04676.14 EGR34413.1 - 5.5e-24 84.9 2.3 5.5e-24 84.9 2.3 3.3 3 1 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 CwfJ_C_1 PF04677.15 EGR34413.1 - 8.1e-24 83.8 1.2 8.1e-24 83.8 1.2 2.4 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 1 TraK PF06586.11 EGR34413.1 - 0.1 12.3 0.7 0.15 11.7 0.7 1.2 1 0 0 1 1 1 0 TraK protein Thioredoxin PF00085.20 EGR34414.1 - 0.01 15.8 6.0 0.12 12.4 0.0 3.7 3 1 0 3 3 3 0 Thioredoxin MFS_1 PF07690.16 EGR34415.1 - 3.6e-54 184.0 35.7 1.4e-38 132.7 19.2 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGR34415.1 - 5.2e-10 38.8 28.8 5.1e-08 32.2 28.5 3.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_3 PF05977.13 EGR34415.1 - 1.4e-05 23.7 6.2 0.02 13.3 0.2 3.1 2 1 0 3 3 3 3 Transmembrane secretion effector OATP PF03137.20 EGR34415.1 - 0.00098 17.5 2.5 0.00098 17.5 2.5 3.9 1 1 1 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_1_like PF12832.7 EGR34415.1 - 0.002 17.0 6.7 0.002 17.0 6.7 3.3 1 1 0 2 2 2 1 MFS_1 like family His_Phos_2 PF00328.22 EGR34416.1 - 1.7e-26 93.5 9.9 4e-25 89.0 8.7 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Neurensin PF14927.6 EGR34416.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Neurensin IZUMO PF15005.6 EGR34416.1 - 0.62 10.6 3.4 1.4 9.5 0.9 2.5 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated WD40 PF00400.32 EGR34417.1 - 8.4e-11 42.3 8.4 0.00025 21.7 0.0 6.6 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR34417.1 - 2.7e-05 24.4 0.4 2.7 8.3 0.0 4.9 5 1 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup35_RRM_2 PF14605.6 EGR34417.1 - 0.0029 17.6 0.0 0.011 15.7 0.0 2.1 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 EGR34417.1 - 0.007 16.2 0.0 0.023 14.5 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BBS2_Mid PF14783.6 EGR34417.1 - 0.1 12.6 2.0 2.6 8.1 0.0 4.0 3 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Androgen_recep PF02166.16 EGR34417.1 - 2 7.2 8.2 3 6.6 8.2 1.1 1 0 0 1 1 1 0 Androgen receptor EF-hand_1 PF00036.32 EGR34418.1 - 1.3e-18 65.1 13.1 0.00026 20.3 0.3 6.7 6 0 0 6 6 6 5 EF hand EF-hand_7 PF13499.6 EGR34418.1 - 2.2e-17 63.3 12.5 3.3e-07 30.7 0.3 4.1 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.6 EGR34418.1 - 1e-16 59.3 11.8 0.00032 20.4 0.4 6.7 6 0 0 6 6 6 4 EF-hand domain EF-hand_5 PF13202.6 EGR34418.1 - 6.9e-09 34.8 13.5 0.091 12.3 0.3 5.6 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 EGR34418.1 - 0.00036 20.3 9.5 0.12 12.3 0.1 4.6 5 0 0 5 5 5 2 EF-hand domain pair BCNT PF07572.12 EGR34418.1 - 0.0097 16.0 4.8 0.041 14.0 1.2 2.6 1 1 1 2 2 2 1 Bucentaur or craniofacial development SPARC_Ca_bdg PF10591.9 EGR34418.1 - 0.02 15.2 9.7 2.1 8.7 2.6 4.0 2 2 2 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EGR34418.1 - 0.024 15.0 0.1 3.6 8.0 0.0 3.5 4 0 0 4 4 4 0 EF-hand domain DUF667 PF05018.13 EGR34420.1 - 5.3e-91 303.4 1.0 6.3e-91 303.1 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF667) UCH PF00443.29 EGR34421.1 - 4.6e-31 108.3 6.9 1.4e-30 106.6 6.9 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase SF-assemblin PF06705.11 EGR34422.1 - 9.9e-06 25.1 42.6 3e-05 23.5 34.9 2.6 1 1 1 2 2 2 2 SF-assemblin/beta giardin BMFP PF04380.13 EGR34422.1 - 0.047 14.2 12.8 0.14 12.6 0.4 3.7 1 1 0 2 2 2 0 Membrane fusogenic activity DUF1464 PF07318.12 EGR34422.1 - 0.27 10.3 2.0 0.57 9.3 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) DUF4413 PF14372.6 EGR34422.1 - 2.2 8.7 11.1 0.4 11.1 0.9 3.6 3 1 0 3 3 3 0 Domain of unknown function (DUF4413) Isy1 PF06246.12 EGR34423.1 - 1.1e-69 234.8 22.4 1.7e-69 234.3 22.4 1.2 1 0 0 1 1 1 1 Isy1-like splicing family DivIC PF04977.15 EGR34423.1 - 0.042 13.6 0.1 0.042 13.6 0.1 3.4 3 0 0 3 3 3 0 Septum formation initiator CAP PF00188.26 EGR34423.1 - 0.29 12.0 0.1 0.29 12.0 0.1 2.1 2 1 0 2 2 2 0 Cysteine-rich secretory protein family DUF4820 PF16091.5 EGR34423.1 - 5.2 6.4 10.8 9 5.6 10.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) U-box PF04564.15 EGR34423.1 - 5.9 7.1 7.0 6.5 7.0 0.9 2.8 2 0 0 2 2 2 0 U-box domain Hydrolase_4 PF12146.8 EGR34424.1 - 1.2e-54 185.1 0.0 1.5e-54 184.8 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR34424.1 - 7.8e-17 61.8 0.0 2.6e-16 60.1 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold LSM PF01423.22 EGR34424.1 - 8.1e-08 31.9 0.0 2.6e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 LSM domain Abhydrolase_6 PF12697.7 EGR34424.1 - 2.2e-06 28.5 0.0 2.7e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thioesterase PF00975.20 EGR34424.1 - 0.0014 18.8 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain PGAP1 PF07819.13 EGR34424.1 - 0.0039 17.0 0.0 3.1 7.5 0.0 2.2 2 0 0 2 2 2 2 PGAP1-like protein Abhydrolase_5 PF12695.7 EGR34424.1 - 0.0051 16.6 0.0 0.022 14.5 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase family UPF0227 PF05728.12 EGR34424.1 - 0.0056 16.7 0.0 0.011 15.6 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0227) Abhydrolase_2 PF02230.16 EGR34424.1 - 0.02 14.7 0.0 0.086 12.6 0.0 2.1 1 1 0 2 2 2 0 Phospholipase/Carboxylesterase Esterase PF00756.20 EGR34424.1 - 0.03 14.0 0.0 0.043 13.5 0.0 1.2 1 0 0 1 1 1 0 Putative esterase Cas_Csx9 PF09658.10 EGR34424.1 - 0.048 12.8 0.0 0.12 11.5 0.0 1.6 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Csx9) Chlorophyllase2 PF12740.7 EGR34424.1 - 0.092 11.6 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Pkinase PF00069.25 EGR34425.1 - 1.3e-22 80.5 4.0 3.1e-12 46.4 0.0 3.7 2 1 1 4 4 4 2 Protein kinase domain CBFD_NFYB_HMF PF00808.23 EGR34425.1 - 1.3e-21 76.6 0.5 2.6e-21 75.7 0.5 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGR34425.1 - 1.9e-17 63.9 0.2 1.9e-17 63.9 0.2 2.6 3 1 0 3 3 3 1 Core histone H2A/H2B/H3/H4 Pkinase_Tyr PF07714.17 EGR34425.1 - 7.6e-12 45.1 0.7 9.5e-06 25.1 0.0 3.1 2 1 1 3 3 3 2 Protein tyrosine kinase TAF PF02969.17 EGR34425.1 - 0.087 13.0 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) NifU_N PF01592.16 EGR34426.1 - 1.9e-49 167.1 0.3 2.2e-49 166.9 0.3 1.0 1 0 0 1 1 1 1 NifU-like N terminal domain Pkinase PF00069.25 EGR34427.1 - 1.4e-63 214.7 1.7 1.4e-63 214.7 1.7 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34427.1 - 1.1e-40 139.5 0.2 2.4e-40 138.5 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR34427.1 - 7.4e-07 28.4 18.1 1.1e-06 27.8 18.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EGR34427.1 - 0.00025 20.2 0.1 0.00059 19.0 0.1 1.6 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EGR34427.1 - 0.0003 20.8 0.0 0.0085 16.0 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGR34427.1 - 0.00069 19.0 0.3 0.0017 17.7 0.3 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGR34427.1 - 0.0018 17.7 0.5 0.0055 16.1 0.0 1.8 1 1 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGR34427.1 - 0.0044 16.6 0.4 0.0044 16.6 0.4 3.5 2 2 1 3 3 3 1 RIO1 family DUF2252 PF10009.9 EGR34427.1 - 1.5 7.8 5.3 5.4 6.0 6.0 1.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2252) Sin_N PF04801.13 EGR34427.1 - 7 5.7 18.7 10 5.2 18.7 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region Pkinase PF00069.25 EGR34428.1 - 5.9e-67 225.8 5.3 7.4e-67 225.5 5.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34428.1 - 3.3e-49 167.5 1.9 3.9e-49 167.3 1.9 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR34428.1 - 2.3e-09 36.6 0.0 4.6e-08 32.3 0.0 2.0 1 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGR34428.1 - 8.1e-06 25.3 3.6 0.0019 17.5 1.3 2.9 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.22 EGR34428.1 - 9.9e-05 22.0 5.8 0.00022 20.9 5.5 1.7 1 1 1 2 2 2 1 RIO1 family ABC1 PF03109.16 EGR34428.1 - 0.0042 17.2 1.2 0.0065 16.6 0.1 1.8 2 0 0 2 2 2 1 ABC1 family YrbL-PhoP_reg PF10707.9 EGR34428.1 - 0.0079 15.7 2.3 0.018 14.6 2.3 1.6 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 EGR34428.1 - 0.17 11.7 0.1 0.27 11.1 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF4284 PF14112.6 EGR34428.1 - 4.1 8.4 11.9 0.8 10.7 0.6 2.8 2 1 1 3 3 3 0 Immunity protein 22 NADH-u_ox-rdase PF10785.9 EGR34429.1 - 2e-19 70.0 0.9 3.4e-19 69.3 0.9 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit DUF5338 PF17273.2 EGR34429.1 - 0.029 14.4 0.2 0.073 13.2 0.2 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5338) Metallophos PF00149.28 EGR34430.1 - 1.1e-31 110.9 0.1 2.7e-31 109.7 0.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ODC_AZ PF02100.17 EGR34431.1 - 3.4e-07 30.2 0.0 5.4e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Ornithine decarboxylase antizyme HIPIP PF01355.17 EGR34431.1 - 0.1 13.0 2.0 0.18 12.2 2.0 1.3 1 0 0 1 1 1 0 High potential iron-sulfur protein Lig_chan PF00060.26 EGR34431.1 - 0.22 11.3 0.9 0.38 10.6 0.9 1.3 1 0 0 1 1 1 0 Ligand-gated ion channel C2 PF00168.30 EGR34432.1 - 1.6e-16 60.5 0.3 2.7e-16 59.7 0.3 1.4 1 0 0 1 1 1 1 C2 domain DASH_Dam1 PF08653.10 EGR34433.1 - 0.13 12.1 1.3 11 6.0 0.1 2.8 2 0 0 2 2 2 0 DASH complex subunit Dam1 Phospholip_A2_2 PF05826.12 EGR34433.1 - 0.63 10.3 3.4 0.54 10.5 0.4 2.1 1 1 1 2 2 2 0 Phospholipase A2 DUF1241 PF06840.11 EGR34433.1 - 1 9.0 15.5 0.23 11.1 3.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1241) Kinesin PF00225.23 EGR34434.1 - 5.3e-105 351.0 2.3 5.3e-105 351.0 2.3 4.1 3 1 2 5 5 5 1 Kinesin motor domain Microtub_bd PF16796.5 EGR34434.1 - 8e-28 97.3 0.6 8e-28 97.3 0.6 4.1 4 2 1 5 5 5 1 Microtubule binding TNF PF00229.18 EGR34435.1 - 0.069 13.1 0.5 0.61 10.0 0.4 2.5 2 0 0 2 2 2 0 TNF(Tumour Necrosis Factor) family PIG-L PF02585.17 EGR34437.1 - 2.4e-17 63.8 0.0 4.2e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glucosamine_iso PF01182.20 EGR34437.1 - 0.0021 18.0 0.0 0.0042 17.0 0.0 1.4 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Furin-like_2 PF15913.5 EGR34438.1 - 1.3e-16 60.6 145.7 1.4e-06 28.4 15.9 8.8 1 1 7 8 8 8 6 Furin-like repeat, cysteine-rich ERp29_N PF07912.13 EGR34438.1 - 0.032 14.4 0.3 0.1 12.8 0.3 1.8 1 0 0 1 1 1 0 ERp29, N-terminal domain RIBIOP_C PF04950.12 EGR34439.1 - 1.1e-90 304.1 7.9 1.1e-90 304.1 7.9 1.7 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EGR34439.1 - 2.1e-14 53.4 0.0 7e-14 51.7 0.0 2.0 1 0 0 1 1 1 1 AARP2CN (NUC121) domain MFS_1 PF07690.16 EGR34440.1 - 6.4e-33 114.1 26.2 6.4e-33 114.1 26.2 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGR34440.1 - 1.8e-06 27.1 2.4 1.8e-06 27.1 2.4 3.2 1 1 1 3 3 3 2 Sugar (and other) transporter MFS_3 PF05977.13 EGR34440.1 - 2.1 6.7 6.7 0.28 9.5 0.2 2.3 3 0 0 3 3 3 0 Transmembrane secretion effector ANAPC4_WD40 PF12894.7 EGR34441.1 - 0.0038 17.5 0.0 0.021 15.1 0.0 2.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Kinesin PF00225.23 EGR34442.1 - 1.3e-110 369.4 5.4 2.1e-110 368.8 5.4 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR34442.1 - 1e-27 96.9 2.3 1e-27 96.9 2.3 2.0 2 0 0 2 2 2 1 Microtubule binding DUF226 PF02890.14 EGR34442.1 - 4.5 7.3 7.7 0.84 9.6 0.5 3.1 3 1 0 3 3 3 0 Borrelia family of unknown function DUF226 CPSase_L_D2 PF02786.17 EGR34443.1 - 1.7e-74 249.9 0.0 3.2e-74 249.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_C PF02785.19 EGR34443.1 - 8.2e-35 119.2 0.0 1.6e-34 118.2 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 EGR34443.1 - 2.8e-32 111.6 0.1 1e-31 109.7 0.0 2.0 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_lipoyl PF00364.22 EGR34443.1 - 4.1e-18 65.0 4.2 6e-18 64.4 3.1 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EGR34443.1 - 5.2e-11 42.2 1.0 1.8e-06 27.7 0.1 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like Dala_Dala_lig_C PF07478.13 EGR34443.1 - 8.2e-11 41.8 0.1 2.7e-10 40.1 0.1 1.9 2 0 0 2 2 2 1 D-ala D-ala ligase C-terminus ATP-grasp_3 PF02655.14 EGR34443.1 - 2.6e-05 24.3 0.1 5.2e-05 23.3 0.1 1.5 1 0 0 1 1 1 1 ATP-grasp domain HlyD_3 PF13437.6 EGR34443.1 - 4.1e-05 24.2 1.6 0.1 13.3 0.0 3.4 3 0 0 3 3 3 2 HlyD family secretion protein HlyD_D23 PF16576.5 EGR34443.1 - 0.0026 17.0 0.6 0.9 8.7 0.1 2.5 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion GARS_A PF01071.19 EGR34443.1 - 0.0092 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.6 EGR34443.1 - 0.028 14.0 0.9 0.055 13.1 0.1 1.9 2 0 0 2 2 2 0 ATP-grasp domain Guanylate_cyc PF00211.20 EGR34444.1 - 4.6e-80 267.6 1.9 3.9e-40 137.4 0.2 2.5 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Bac_globin PF01152.21 EGR34445.1 - 6.4e-49 165.1 5.1 3.9e-20 72.2 0.1 5.0 4 1 1 5 5 5 4 Bacterial-like globin Protoglobin PF11563.8 EGR34445.1 - 1.1e-06 28.6 0.4 0.047 13.6 0.0 3.8 3 1 0 3 3 3 2 Protoglobin AhpC-TSA PF00578.21 EGR34445.1 - 0.00021 21.2 0.4 0.083 12.8 0.0 3.2 2 1 1 3 3 3 1 AhpC/TSA family LCIB_C_CA PF18599.1 EGR34445.1 - 0.015 14.6 3.1 2.9 7.1 0.2 3.0 3 0 0 3 3 3 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Cas_Csd1 PF09709.10 EGR34445.1 - 0.049 12.3 0.0 0.086 11.5 0.0 1.3 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csd1) DUF2746 PF10874.8 EGR34445.1 - 0.076 13.5 0.8 2.1 8.8 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2746) STI1 PF17830.1 EGR34445.1 - 0.077 12.9 8.3 12 5.9 0.1 4.9 5 0 0 5 5 5 0 STI1 domain GatB_Yqey PF02637.18 EGR34445.1 - 2.5 8.0 7.8 0.72 9.7 0.1 3.6 2 1 1 4 4 4 0 GatB domain Laminin_G_3 PF13385.6 EGR34446.1 - 4.5e-06 26.9 0.1 9.8e-06 25.8 0.1 1.5 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily BTK PF00779.19 EGR34446.1 - 0.014 15.2 13.5 0.03 14.1 3.4 3.1 2 1 0 2 2 2 0 BTK motif BUD22 PF09073.10 EGR34448.1 - 0.022 14.1 40.5 0.025 14.0 40.5 1.2 1 0 0 1 1 1 0 BUD22 DotA PF11388.8 EGR34450.1 - 0.021 15.0 0.7 0.22 11.8 0.1 2.3 1 1 1 2 2 2 0 Phagosome trafficking protein DotA DUF5487 PF17589.2 EGR34451.1 - 0.054 13.7 0.1 1e+02 3.2 0.0 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5487) DUF1348 PF07080.11 EGR34451.1 - 0.15 12.0 0.1 0.27 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1348) CW_7 PF08230.11 EGR34451.1 - 0.84 9.4 3.6 96 2.8 0.1 3.3 3 0 0 3 3 3 0 CW_7 repeat Coprogen_oxidas PF01218.18 EGR34452.1 - 4.4e-92 308.0 4.4 4.8e-92 307.8 4.4 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Kinesin PF00225.23 EGR34453.1 - 1.5e-102 343.0 8.8 1.5e-102 343.0 8.8 2.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGR34453.1 - 4.2e-21 75.5 8.6 4.2e-21 75.5 8.6 4.0 2 1 1 3 3 3 1 Microtubule binding IF4E PF01652.18 EGR34454.1 - 4.8e-15 55.7 1.0 6.3e-15 55.3 1.0 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E GP17 PF17420.2 EGR34454.1 - 0.082 13.1 2.2 0.18 12.0 0.3 2.1 2 0 0 2 2 2 0 Superinfection exclusion gene product 17 Pkinase PF00069.25 EGR34455.1 - 5e-30 104.8 1.2 5e-30 104.8 1.2 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34455.1 - 1.1e-17 64.2 0.0 1.6e-17 63.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Seadorna_VP7 PF07387.11 EGR34455.1 - 3.4e-05 23.0 0.1 5.5e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 EGR34455.1 - 8.8e-05 21.9 0.3 0.00026 20.4 0.3 1.8 1 1 0 1 1 1 1 Kinase-like Oxysterol_BP PF01237.18 EGR34457.1 - 4.4e-33 114.6 0.3 1.1e-32 113.3 0.3 1.7 1 1 0 1 1 1 1 Oxysterol-binding protein Ribosomal_L29e PF01779.17 EGR34458.1 - 5.7e-19 68.2 10.3 5.7e-19 68.2 10.3 1.7 2 0 0 2 2 2 1 Ribosomal L29e protein family DUF2177 PF09945.9 EGR34459.1 - 4.5 7.4 8.6 0.45 10.6 3.3 2.0 2 1 1 3 3 3 0 Predicted membrane protein (DUF2177) CTP_transf_1 PF01148.20 EGR34460.1 - 7.2e-74 248.9 26.2 1e-73 248.4 26.2 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Tubulin PF00091.25 EGR34461.1 - 7.9e-40 137.2 7.9 6.5e-27 95.0 3.9 2.5 1 1 1 2 2 2 2 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGR34461.1 - 1.9 8.6 6.8 2.9 8.1 0.8 2.4 2 0 0 2 2 2 0 Tubulin C-terminal domain DUF1948 PF09185.10 EGR34461.1 - 6.9 6.5 9.8 0.47 10.3 3.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1948) TPR_2 PF07719.17 EGR34463.1 - 1.4e-18 65.4 3.6 2.8e-05 23.9 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGR34463.1 - 5.2e-17 60.9 11.5 2.6e-07 30.2 0.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGR34463.1 - 6.2e-13 49.1 3.9 2.4e-06 28.0 0.9 3.1 2 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGR34463.1 - 1e-12 47.5 10.0 2.9e-09 36.5 0.6 3.9 2 2 2 4 4 4 2 TPR repeat TPR_8 PF13181.6 EGR34463.1 - 4.5e-11 42.0 9.6 0.011 15.9 0.0 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGR34463.1 - 6.8e-11 42.3 4.3 0.001 19.3 0.1 4.4 1 1 3 4 4 4 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR34463.1 - 4.7e-10 39.6 2.3 0.00035 20.7 0.1 2.4 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGR34463.1 - 5.3e-10 39.3 0.4 0.028 15.0 0.0 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGR34463.1 - 4.3e-07 30.2 0.0 0.18 12.7 0.0 3.9 2 2 2 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGR34463.1 - 2.1e-05 25.1 0.0 0.9 10.2 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGR34463.1 - 3.3e-05 23.9 7.8 0.0084 16.4 0.6 3.8 4 1 0 4 4 3 2 Tetratricopeptide repeat TOM20_plant PF06552.12 EGR34463.1 - 3.9e-05 23.5 3.4 9.2e-05 22.3 1.7 2.2 1 1 1 2 2 2 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_7 PF13176.6 EGR34463.1 - 0.00034 20.4 0.7 14 6.0 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 EGR34463.1 - 0.0094 16.3 4.4 1.2 9.5 1.8 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat Minor_capsid_1 PF10665.9 EGR34463.1 - 0.026 14.7 0.1 0.041 14.1 0.1 1.3 1 0 0 1 1 1 0 Minor capsid protein Alkyl_sulf_dimr PF14863.6 EGR34463.1 - 0.2 12.1 2.4 0.48 10.9 1.7 1.9 1 1 0 2 2 2 0 Alkyl sulfatase dimerisation Fis1_TPR_C PF14853.6 EGR34463.1 - 0.71 10.0 6.3 2.8 8.1 0.1 3.6 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Vta1_C PF18097.1 EGR34463.1 - 5.8 6.7 8.1 3.2 7.5 0.0 3.7 5 0 0 5 5 5 0 Vta1 C-terminal domain TPR_2 PF07719.17 EGR34464.1 - 1.3e-23 81.1 19.4 0.00013 21.8 0.1 7.7 7 1 0 7 7 7 6 Tetratricopeptide repeat TPR_1 PF00515.28 EGR34464.1 - 2.1e-22 77.9 34.7 0.00078 19.2 0.1 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_8 PF13181.6 EGR34464.1 - 1.3e-20 71.8 32.4 0.0045 17.1 0.3 8.2 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_12 PF13424.6 EGR34464.1 - 5.3e-16 58.7 8.1 0.026 14.8 0.2 6.4 4 3 1 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGR34464.1 - 3.6e-13 48.9 15.1 0.00025 21.2 0.1 6.6 8 1 0 8 8 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGR34464.1 - 3.9e-13 49.7 4.5 0.00024 21.6 0.1 4.3 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGR34464.1 - 6e-13 48.2 30.2 0.00014 21.5 0.1 7.3 6 2 2 8 8 8 4 TPR repeat TPR_7 PF13176.6 EGR34464.1 - 1.6e-11 43.4 0.7 0.11 12.6 0.0 6.0 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR34464.1 - 1.1e-10 41.6 12.8 0.00022 21.4 0.8 4.1 3 1 1 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EGR34464.1 - 5.6e-09 36.1 0.0 3.1 8.9 0.0 5.3 3 2 2 5 5 5 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGR34464.1 - 5.4e-07 30.2 0.0 0.35 11.6 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGR34464.1 - 2e-06 27.4 0.0 0.00034 20.1 0.0 2.4 2 2 0 2 2 2 1 MalT-like TPR region TPR_6 PF13174.6 EGR34464.1 - 5.1e-06 26.8 13.4 0.053 14.2 0.0 6.7 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGR34464.1 - 0.00029 20.1 0.1 0.027 13.7 0.0 2.5 2 1 1 3 3 3 1 Tetratricopeptide repeat SPO22 PF08631.10 EGR34464.1 - 0.052 13.0 4.4 0.81 9.1 0.2 2.7 1 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like ATP_transf PF09830.9 EGR34464.1 - 0.15 12.3 0.0 0.42 10.8 0.0 1.8 2 0 0 2 2 1 0 ATP adenylyltransferase Sel1 PF08238.12 EGR34464.1 - 0.18 12.5 4.5 17 6.3 0.1 4.4 5 0 0 5 5 4 0 Sel1 repeat CAF1 PF04857.20 EGR34464.1 - 1.1 8.3 8.4 19 4.3 8.4 2.0 1 1 0 1 1 1 0 CAF1 family ribonuclease HTH_Bact PF18768.1 EGR34464.1 - 1.2 8.8 11.4 3.6 7.2 0.3 4.3 3 1 1 4 4 4 0 Helix-turn-helix bacterial domain Fis1_TPR_C PF14853.6 EGR34464.1 - 2.3 8.4 9.9 5.3 7.2 0.3 4.1 5 0 0 5 5 4 0 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.12 EGR34464.1 - 3 8.0 28.4 0.95 9.5 1.6 5.9 6 1 0 6 6 6 0 Tetratricopeptide repeat Pkinase PF00069.25 EGR34466.1 - 2.1e-33 115.8 0.6 2.1e-33 115.8 0.6 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34466.1 - 6.1e-19 68.3 0.1 1.6e-18 67.0 0.1 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.7 EGR34466.1 - 9.4e-15 55.0 9.2 4.6e-09 36.7 3.8 2.6 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGR34466.1 - 3.1e-13 49.9 4.3 1.1e-05 25.8 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGR34466.1 - 2.9e-12 45.6 4.3 0.0062 16.9 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EGR34466.1 - 4.2e-11 42.9 3.8 4.6e-05 23.6 0.1 3.6 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EGR34466.1 - 5.4e-11 42.4 9.6 0.0033 17.8 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat OmdA PF13376.6 EGR34466.1 - 0.24 11.4 1.9 0.82 9.7 1.9 1.9 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated cNMP_binding PF00027.29 EGR34467.1 - 8.4e-18 64.2 0.0 1.4e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans_2 PF07885.16 EGR34467.1 - 1.9e-11 43.8 4.1 3.4e-11 43.0 4.1 1.4 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGR34467.1 - 8.4e-05 21.9 0.7 0.00015 21.1 0.7 1.4 1 0 0 1 1 1 1 Ion transport protein Choline_transpo PF04515.12 EGR34468.1 - 2.7e-22 79.4 12.6 2.7e-22 79.4 12.6 3.0 3 0 0 3 3 3 1 Plasma-membrane choline transporter Lipoprotein_19 PF13617.6 EGR34468.1 - 0.33 10.8 3.2 0.39 10.5 1.5 2.0 2 0 0 2 2 2 0 YnbE-like lipoprotein CCSMST1 PF15013.6 EGR34468.1 - 5.9 7.1 6.7 28 5.0 0.0 3.2 3 0 0 3 3 3 0 CCSMST1 family Anoctamin PF04547.12 EGR34469.1 - 4.6e-41 141.1 16.1 4.6e-41 141.1 16.1 2.4 2 1 0 2 2 2 1 Calcium-activated chloride channel DUF3566 PF12089.8 EGR34469.1 - 0.093 13.1 0.4 0.3 11.4 0.4 1.8 1 0 0 1 1 1 0 Transmembrane domain of unknown function (DUF3566) PPO1_DWL PF12142.8 EGR34469.1 - 0.2 11.5 4.3 3.7 7.4 0.0 3.1 3 0 0 3 3 3 0 Polyphenol oxidase middle domain zf-CCCH PF00642.24 EGR34470.1 - 1.2e-05 25.1 9.6 9.2e-05 22.3 1.6 3.9 4 0 0 4 4 4 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGR34470.1 - 0.00031 20.7 11.8 0.0058 16.6 2.2 4.2 4 0 0 4 4 4 2 Zinc finger domain zf-CCCH_4 PF18044.1 EGR34470.1 - 0.0063 16.3 1.8 0.0063 16.3 1.8 3.5 4 0 0 4 4 4 1 CCCH-type zinc finger ANAPC5 PF12862.7 EGR34470.1 - 0.076 13.1 1.8 0.26 11.4 0.1 2.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 TPR_1 PF00515.28 EGR34470.1 - 0.079 12.8 0.3 0.85 9.5 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGR34470.1 - 0.14 12.5 0.1 7 7.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Nab2p_Zf1 PF18260.1 EGR34470.1 - 0.46 10.4 15.4 2.7 8.0 0.7 3.6 3 0 0 3 3 3 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 TTL PF03133.15 EGR34471.1 - 1.2e-39 136.2 12.6 1.5e-39 135.9 12.6 1.1 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR34471.1 - 1.8e-09 37.2 1.9 2.9e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR34471.1 - 1.7e-07 30.8 4.9 0.00063 19.1 0.9 3.1 2 1 1 3 3 3 2 Sugar-transfer associated ATP-grasp CPSase_L_D2 PF02786.17 EGR34471.1 - 0.045 13.2 0.0 0.09 12.3 0.0 1.5 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase L chain, ATP binding domain GSH-S_ATP PF02955.16 EGR34471.1 - 0.13 11.7 0.1 0.26 10.7 0.1 1.5 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain P5CR_dimer PF14748.6 EGR34472.1 - 2.8e-34 117.5 0.0 4.7e-34 116.7 0.0 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EGR34472.1 - 4.8e-14 52.7 0.1 8.7e-14 51.9 0.1 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EGR34472.1 - 0.00013 21.6 0.1 0.00023 20.8 0.1 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 EGR34472.1 - 0.0072 16.3 0.1 0.021 14.8 0.0 1.8 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GFO_IDH_MocA PF01408.22 EGR34472.1 - 0.097 13.5 0.0 0.23 12.3 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Shikimate_DH PF01488.20 EGR34472.1 - 0.14 12.2 0.0 0.23 11.5 0.0 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase AAA PF00004.29 EGR34473.1 - 1.5e-12 48.1 0.1 2.7e-12 47.3 0.1 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.11 EGR34473.1 - 5.3e-12 46.0 0.0 1.6e-11 44.5 0.0 1.8 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.6 EGR34473.1 - 1.8e-11 44.1 0.0 4.3e-09 36.4 0.1 2.3 1 1 1 2 2 2 1 DNA polymerase III, delta subunit DNA_pol3_delta PF06144.13 EGR34473.1 - 1.5e-07 31.3 0.2 3.1e-07 30.3 0.2 1.5 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 EGR34473.1 - 3.2e-06 27.6 0.2 0.00062 20.2 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 EGR34473.1 - 4.3e-05 23.5 0.0 0.00026 21.0 0.0 2.1 1 1 1 2 2 2 1 Rad17 P-loop domain AAA_22 PF13401.6 EGR34473.1 - 9.6e-05 22.7 0.9 0.085 13.1 0.9 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGR34473.1 - 0.00013 22.0 0.0 0.00024 21.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EGR34473.1 - 0.0012 18.3 0.3 0.19 11.1 0.0 2.5 3 0 0 3 3 3 1 Bacterial TniB protein AAA_24 PF13479.6 EGR34473.1 - 0.0016 18.2 0.0 0.0033 17.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGR34473.1 - 0.0029 17.5 0.0 0.0039 17.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGR34473.1 - 0.003 17.0 0.0 0.0082 15.5 0.0 1.8 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGR34473.1 - 0.0044 17.0 0.5 0.028 14.4 0.5 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGR34473.1 - 0.0069 16.1 0.0 0.015 15.0 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EGR34473.1 - 0.02 14.6 0.1 0.061 13.1 0.1 1.8 1 1 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 EGR34473.1 - 0.025 14.5 0.3 3.2 7.7 0.0 2.3 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.22 EGR34473.1 - 0.025 15.0 0.0 0.077 13.4 0.0 1.8 1 1 0 1 1 1 0 RNA helicase Viral_helicase1 PF01443.18 EGR34473.1 - 0.034 13.9 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_3 PF07726.11 EGR34473.1 - 0.035 13.9 0.0 0.06 13.2 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EGR34473.1 - 0.038 14.3 0.4 0.29 11.4 0.4 2.3 1 1 0 1 1 1 0 AAA domain SNF2_N PF00176.23 EGR34473.1 - 0.054 12.2 0.1 2.3 6.8 0.0 2.2 1 1 1 2 2 2 0 SNF2 family N-terminal domain AAA_assoc_2 PF16193.5 EGR34473.1 - 0.064 13.6 0.0 0.2 12.0 0.0 1.9 2 0 0 2 2 1 0 AAA C-terminal domain Myc-LZ PF02344.15 EGR34474.1 - 0.011 15.8 1.0 0.041 14.0 0.0 2.4 2 0 0 2 2 2 0 Myc leucine zipper domain Musclin PF11037.8 EGR34474.1 - 0.11 12.4 0.3 0.16 11.9 0.3 1.3 1 0 0 1 1 1 0 Insulin-resistance promoting peptide in skeletal muscle Spt4 PF06093.13 EGR34475.1 - 2.9e-06 27.3 2.8 0.00017 21.6 0.5 2.4 1 1 1 2 2 2 2 Spt4/RpoE2 zinc finger Opiods_neuropep PF01160.18 EGR34475.1 - 0.089 12.9 3.2 0.097 12.8 0.8 2.0 2 0 0 2 2 2 0 Vertebrate endogenous opioids neuropeptide UCH PF00443.29 EGR34476.1 - 1.5e-49 168.9 15.0 2.1e-49 168.3 15.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGR34476.1 - 8.6e-25 88.0 18.3 1.5e-24 87.2 18.3 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-C2H2_2 PF12756.7 EGR34476.1 - 0.00099 19.4 0.4 0.00099 19.4 0.4 4.0 3 2 1 4 4 4 1 C2H2 type zinc-finger (2 copies) MatE PF01554.18 EGR34477.1 - 5.4e-13 48.9 18.0 9.3e-13 48.1 18.0 1.4 1 0 0 1 1 1 1 MatE RNA_pol_N PF01194.17 EGR34478.1 - 0.0025 18.1 0.0 0.0047 17.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Ribosomal_S27e PF01667.17 EGR34478.1 - 0.0041 16.8 1.4 0.006 16.3 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein S27 TF_Zn_Ribbon PF08271.12 EGR34478.1 - 0.0053 16.2 1.0 0.011 15.2 1.0 1.6 1 0 0 1 1 1 1 TFIIB zinc-binding NusA_N PF08529.11 EGR34478.1 - 0.015 15.7 0.1 0.016 15.6 0.1 1.2 1 0 0 1 1 1 0 NusA N-terminal domain RNA_POL_M_15KD PF02150.16 EGR34478.1 - 0.016 15.1 0.7 0.036 14.0 0.7 1.6 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit Elf1 PF05129.13 EGR34478.1 - 0.032 14.3 2.5 0.054 13.5 2.5 1.3 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like DUF1660 PF07874.11 EGR34478.1 - 0.052 14.0 1.6 0.074 13.6 0.7 1.7 1 1 1 2 2 2 0 Prophage protein (DUF1660) Synaptobrevin PF00957.21 EGR34479.1 - 1.8e-19 69.3 5.0 3.1e-19 68.5 5.0 1.5 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGR34479.1 - 5.8e-17 61.5 2.9 1e-16 60.7 2.9 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain SRI PF08236.11 EGR34479.1 - 0.02 15.0 0.2 0.058 13.6 0.1 1.8 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain CHASE7 PF17151.4 EGR34479.1 - 0.062 12.9 0.7 0.091 12.3 0.7 1.3 1 0 0 1 1 1 0 Periplasmic sensor domain DUF903 PF06004.12 EGR34479.1 - 0.063 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF903) PUF PF00806.19 EGR34480.1 - 2.6e-45 149.6 26.4 5.4e-08 32.1 0.3 7.5 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat CPL PF08144.11 EGR34480.1 - 0.0025 18.1 5.9 3.9 7.8 0.4 4.3 1 1 2 4 4 4 2 CPL (NUC119) domain DUF445 PF04286.12 EGR34480.1 - 0.63 9.8 6.6 0.49 10.1 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF445) SAYSvFN PF10260.9 EGR34481.1 - 4.5e-19 68.1 0.0 6.8e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) SEC-C PF02810.15 EGR34481.1 - 0.00011 22.0 14.4 0.00011 22.0 14.4 2.0 2 0 0 2 2 2 1 SEC-C motif POX PF07526.11 EGR34481.1 - 0.077 13.6 0.8 0.12 12.9 0.8 1.3 1 0 0 1 1 1 0 Associated with HOX Methyltr_RsmB-F PF01189.17 EGR34482.1 - 4.7e-36 124.3 4.8 3.2e-35 121.6 0.0 3.1 2 1 0 2 2 2 1 16S rRNA methyltransferase RsmB/F DUF5308 PF17233.2 EGR34482.1 - 0.011 16.0 2.6 0.025 14.8 2.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5308) CDC45 PF02724.14 EGR34482.1 - 0.097 10.9 14.7 0.23 9.7 14.7 1.6 1 0 0 1 1 1 0 CDC45-like protein RP-C_C PF11800.8 EGR34482.1 - 0.12 12.4 10.5 0.31 11.1 10.5 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region Hydin_ADK PF17213.3 EGR34482.1 - 0.43 10.8 10.2 1.1 9.5 10.2 1.6 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Zip PF02535.22 EGR34482.1 - 0.53 9.4 5.3 0.86 8.8 5.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF913 PF06025.12 EGR34482.1 - 0.91 8.4 10.3 1.7 7.5 10.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) MFMR PF07777.11 EGR34482.1 - 1 9.9 0.0 1 9.9 0.0 3.4 3 0 0 3 3 2 0 G-box binding protein MFMR Pex14_N PF04695.13 EGR34482.1 - 1.1 9.9 26.6 0.12 13.0 21.4 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PepSY_TM PF03929.16 EGR34482.1 - 1.5 8.4 3.2 2.7 7.6 3.2 1.3 1 0 0 1 1 1 0 PepSY-associated TM region DUF3391 PF11871.8 EGR34482.1 - 2.2 8.8 15.8 0.21 12.1 9.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) Band_3_cyto PF07565.13 EGR34482.1 - 3.9 7.2 14.1 11 5.7 14.1 1.7 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Serinc PF03348.15 EGR34482.1 - 4.3 6.2 10.7 8.6 5.2 10.7 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) BIRC6 PF12356.8 EGR34482.1 - 4.6 6.7 7.4 12 5.3 7.4 1.6 1 0 0 1 1 1 0 Baculoviral IAP repeat-containing protein 6 DUF4407 PF14362.6 EGR34482.1 - 4.6 6.5 12.2 8.6 5.6 12.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Presenilin PF01080.17 EGR34482.1 - 7 5.3 24.0 1.2 7.9 19.4 1.9 2 0 0 2 2 2 0 Presenilin Peptidase_M8 PF01457.16 EGR34483.1 - 2.8e-38 131.9 0.7 5.2e-38 131.0 0.1 1.6 1 1 1 2 2 2 1 Leishmanolysin EGF_Tenascin PF18720.1 EGR34483.1 - 8.9e-05 22.4 6.7 0.00035 20.5 6.7 2.1 1 0 0 1 1 1 1 Tenascin EGF domain EGF_2 PF07974.13 EGR34483.1 - 0.0033 17.8 11.4 0.0033 17.8 11.4 3.2 3 1 0 3 3 3 1 EGF-like domain Zincin_1 PF06262.11 EGR34483.1 - 0.14 12.3 0.2 0.28 11.3 0.2 1.4 1 0 0 1 1 1 0 Zincin-like metallopeptidase Slx4 PF09494.10 EGR34483.1 - 0.15 12.0 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 Slx4 endonuclease RRM_1 PF00076.22 EGR34484.1 - 7.6e-06 25.7 0.1 8.7e-06 25.5 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGR34484.1 - 0.00022 20.8 0.4 0.00023 20.7 0.4 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Agenet PF05641.12 EGR34484.1 - 0.067 13.7 0.1 0.081 13.4 0.1 1.2 1 0 0 1 1 1 0 Agenet domain RRM_occluded PF16842.5 EGR34484.1 - 0.08 12.8 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 Occluded RNA-recognition motif Mito_carr PF00153.27 EGR34485.1 - 3.1e-49 164.8 1.0 2.3e-20 72.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1685 PF07939.11 EGR34486.1 - 0.43 10.4 2.3 3.2 7.6 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1685) Na_H_Exchanger PF00999.21 EGR34487.1 - 4.3e-51 173.9 38.9 6e-51 173.4 38.9 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family cNMP_binding PF00027.29 EGR34487.1 - 1.8e-05 24.7 0.0 6.3e-05 23.0 0.0 2.1 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain GDP_Man_Dehyd PF16363.5 EGR34489.1 - 6.5e-51 173.7 0.0 7.5e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGR34489.1 - 7.9e-48 163.0 0.0 9.8e-48 162.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGR34489.1 - 2e-14 53.3 0.0 5.3e-12 45.3 0.0 2.2 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGR34489.1 - 1.5e-13 50.6 0.0 4e-13 49.2 0.0 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGR34489.1 - 2.1e-08 33.7 0.0 3.3e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGR34489.1 - 9.4e-08 31.5 0.0 2.4e-07 30.2 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EGR34489.1 - 0.0089 15.5 0.2 1.9 7.9 0.0 2.5 2 0 0 2 2 2 2 short chain dehydrogenase KR PF08659.10 EGR34489.1 - 0.014 15.3 0.0 0.041 13.8 0.0 1.8 1 1 0 1 1 1 0 KR domain HTH_ParB PF17762.1 EGR34489.1 - 0.1 12.5 0.1 0.25 11.2 0.1 1.7 1 0 0 1 1 1 0 HTH domain found in ParB protein UQ_con PF00179.26 EGR34490.1 - 4.9e-55 185.0 0.0 5.5e-55 184.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGR34490.1 - 0.00013 21.7 0.0 0.00016 21.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGR34490.1 - 0.0063 16.8 0.0 0.0082 16.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 EGR34490.1 - 0.025 14.5 0.0 0.038 13.8 0.0 1.3 1 0 0 1 1 1 0 UEV domain Helicase_RecD PF05127.14 EGR34491.1 - 1.3e-53 181.5 0.0 2e-53 180.8 0.0 1.3 1 0 0 1 1 1 1 Helicase GNAT_acetyltr_2 PF13718.6 EGR34491.1 - 1.6e-34 119.3 2.0 2.8e-34 118.5 0.0 2.0 2 0 0 2 2 2 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EGR34491.1 - 9.7e-07 28.7 0.2 9.7e-07 28.7 0.2 2.0 2 0 0 2 2 2 1 Possible tRNA binding domain TBCC_N PF16752.5 EGR34491.1 - 0.088 13.2 7.1 0.78 10.2 0.2 2.3 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain PBECR4 PF18813.1 EGR34491.1 - 0.82 9.8 7.8 0.95 9.7 0.1 2.9 2 1 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease4 DUF4061 PF13270.6 EGR34491.1 - 1.1 9.6 5.7 2.4 8.5 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Pkinase PF00069.25 EGR34492.1 - 9.2e-67 225.2 0.9 9.2e-67 225.2 0.9 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34492.1 - 6.1e-47 160.1 0.1 1.1e-46 159.2 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR34492.1 - 4.8e-07 29.4 0.1 1.4e-06 27.8 0.1 1.9 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR34492.1 - 0.0017 17.7 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR34492.1 - 0.0057 15.5 0.0 0.011 14.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase DUF3713 PF12506.8 EGR34492.1 - 0.55 10.5 8.3 0.3 11.4 5.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3713) DUF5347 PF17282.2 EGR34492.1 - 6 7.2 8.0 1.3 9.4 1.3 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5347) Ras PF00071.22 EGR34493.1 - 3.8e-61 205.4 2.1 8.9e-61 204.2 2.1 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR34493.1 - 1.3e-34 119.0 9.0 5.2e-34 117.0 1.0 2.7 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR34493.1 - 9.9e-14 51.2 1.3 9.9e-14 51.2 1.3 1.8 1 1 1 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR34493.1 - 0.0024 17.9 3.3 0.02 14.9 3.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGR34493.1 - 0.067 13.1 3.4 3.3 7.6 0.1 2.8 1 1 1 3 3 3 0 RsgA GTPase TFX_C PF14601.6 EGR34493.1 - 0.083 12.9 1.1 0.39 10.7 0.2 2.5 1 1 2 3 3 3 0 DNA_binding protein, TFX, C-term GTP_EFTU PF00009.27 EGR34493.1 - 1.5 8.3 5.6 0.93 9.0 3.2 1.8 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EGR34494.1 - 8.1e-35 120.3 0.3 8.8e-17 61.9 0.1 3.0 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGR34494.1 - 2.7e-11 43.3 5.6 0.00014 21.4 0.0 4.0 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGR34494.1 - 2.3e-10 40.8 9.2 0.15 11.8 0.2 4.2 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system RLI PF04068.15 EGR34494.1 - 2.8e-10 39.8 6.5 2.8e-10 39.8 6.5 1.9 2 0 0 2 2 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI AAA_24 PF13479.6 EGR34494.1 - 6.6e-06 26.0 0.1 0.023 14.4 0.0 2.6 2 1 0 2 2 2 2 AAA domain Fer4 PF00037.27 EGR34494.1 - 7.3e-06 25.6 3.6 7.3e-06 25.6 3.6 2.6 3 0 0 3 3 3 1 4Fe-4S binding domain AAA_16 PF13191.6 EGR34494.1 - 1.2e-05 25.7 0.0 0.045 14.1 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGR34494.1 - 1.9e-05 24.6 0.1 0.076 12.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_15 PF13175.6 EGR34494.1 - 3.8e-05 23.6 5.1 0.14 11.9 0.1 3.3 3 1 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 EGR34494.1 - 7.4e-05 23.2 0.1 0.095 13.1 0.0 2.5 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EGR34494.1 - 8.5e-05 23.1 4.8 0.079 13.4 0.1 2.5 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGR34494.1 - 8.5e-05 22.2 0.5 0.39 10.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EGR34494.1 - 0.00013 22.2 1.1 0.036 14.3 0.0 2.9 2 2 0 2 2 2 1 AAA domain Rad17 PF03215.15 EGR34494.1 - 0.00021 21.3 0.0 0.08 12.8 0.0 2.5 2 0 0 2 2 2 1 Rad17 P-loop domain Fer4_6 PF12837.7 EGR34494.1 - 0.00057 19.8 3.5 0.00057 19.8 3.5 2.4 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4_21 PF14697.6 EGR34494.1 - 0.00093 19.3 14.4 0.0019 18.3 14.4 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain NACHT PF05729.12 EGR34494.1 - 0.0011 19.0 0.4 0.16 11.9 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_28 PF13521.6 EGR34494.1 - 0.0012 19.1 0.0 0.42 10.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGR34494.1 - 0.0014 19.2 0.0 2.9 8.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 EGR34494.1 - 0.0035 16.9 0.1 0.038 13.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_14 PF13173.6 EGR34494.1 - 0.0041 17.2 0.1 1.5 8.9 0.0 3.2 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.22 EGR34494.1 - 0.0048 16.6 2.3 0.23 11.1 0.1 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_10 PF13237.6 EGR34494.1 - 0.0048 17.0 2.1 0.0048 17.0 2.1 2.2 1 1 1 2 2 2 2 4Fe-4S dicluster domain RNA_helicase PF00910.22 EGR34494.1 - 0.0052 17.1 0.1 1.5 9.3 0.0 2.9 3 0 0 3 3 2 1 RNA helicase NB-ARC PF00931.22 EGR34494.1 - 0.0085 15.3 0.4 3.3 6.8 0.0 2.9 3 0 0 3 3 3 1 NB-ARC domain MMR_HSR1 PF01926.23 EGR34494.1 - 0.0091 16.1 0.6 1.7 8.8 0.0 2.8 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 EGR34494.1 - 0.0095 15.7 0.3 0.65 9.7 0.0 2.5 2 1 0 2 2 2 1 AAA domain Fer4_16 PF13484.6 EGR34494.1 - 0.011 16.6 0.2 0.011 16.6 0.2 2.5 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain Roc PF08477.13 EGR34494.1 - 0.011 15.9 0.1 0.19 12.0 0.0 2.6 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase VirE PF05272.11 EGR34494.1 - 0.011 15.4 0.1 6.4 6.5 0.0 2.5 2 0 0 2 2 2 0 Virulence-associated protein E TsaE PF02367.17 EGR34494.1 - 0.013 15.5 0.1 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EGR34494.1 - 0.016 15.3 0.4 3.2 7.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain Fer4_7 PF12838.7 EGR34494.1 - 0.018 15.6 2.6 0.018 15.6 2.6 2.0 1 1 2 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGR34494.1 - 0.024 14.8 14.6 0.049 13.8 14.6 1.5 1 0 0 1 1 1 0 4Fe-4S dicluster domain SbcCD_C PF13558.6 EGR34494.1 - 0.024 14.9 0.0 5 7.4 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Septin PF00735.18 EGR34494.1 - 0.048 12.9 0.0 0.83 8.9 0.0 2.2 2 0 0 2 2 2 0 Septin DLIC PF05783.11 EGR34494.1 - 0.051 12.4 0.2 0.18 10.6 0.0 1.8 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Dynamin_N PF00350.23 EGR34494.1 - 0.12 12.4 0.4 6.4 6.8 0.0 3.2 4 0 0 4 4 3 0 Dynamin family AAA_25 PF13481.6 EGR34494.1 - 0.24 10.9 0.2 2.4 7.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 EGR34494.1 - 0.48 10.1 2.8 29 4.2 0.0 3.3 4 0 0 4 4 3 0 Thymidylate kinase Fer4_4 PF12800.7 EGR34494.1 - 1.2 9.8 15.4 0.072 13.6 2.2 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Arm PF00514.23 EGR34495.1 - 1.8e-58 192.9 12.0 3.3e-10 39.6 0.1 9.2 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGR34495.1 - 4e-15 55.9 0.0 0.00097 19.6 0.0 5.5 4 1 1 5 5 5 3 HEAT-like repeat Arm_3 PF16186.5 EGR34495.1 - 6.2e-13 48.1 1.3 1.3e-11 43.8 0.7 3.0 3 0 0 3 3 3 1 Atypical Arm repeat HEAT_2 PF13646.6 EGR34495.1 - 2.6e-08 34.1 0.0 0.0042 17.5 0.0 4.7 2 2 3 5 5 5 2 HEAT repeats HEAT PF02985.22 EGR34495.1 - 8.2e-07 28.8 6.8 0.06 13.6 0.0 6.1 6 0 0 6 6 6 2 HEAT repeat IBB PF01749.20 EGR34495.1 - 6.9e-06 26.4 6.0 1.8e-05 25.1 6.0 1.7 1 0 0 1 1 1 1 Importin beta binding domain V-ATPase_H_C PF11698.8 EGR34495.1 - 9.7e-05 22.5 0.3 0.28 11.3 0.0 3.6 3 1 0 3 3 3 2 V-ATPase subunit H NopRA1 PF16201.5 EGR34495.1 - 0.0025 17.4 0.2 12 5.5 0.0 4.6 3 2 2 5 5 5 1 Nucleolar pre-ribosomal-associated protein 1 Cnd1 PF12717.7 EGR34495.1 - 0.016 15.3 0.3 2.6 8.1 0.1 3.2 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.9 EGR34495.1 - 0.11 12.5 13.5 0.29 11.2 0.3 4.8 4 2 3 7 7 7 0 Spinocerebellar ataxia type 10 protein domain Peptidase_M8 PF01457.16 EGR34496.1 - 2.1e-32 112.5 0.0 2.8e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Leishmanolysin Ntox34 PF15606.6 EGR34496.1 - 0.22 11.7 0.3 5.8 7.1 0.0 2.9 3 0 0 3 3 3 0 Bacterial toxin 34 SIMPL PF04402.14 EGR34497.1 - 6.3e-26 92.1 8.2 1.1e-25 91.3 8.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF541) RraB PF06877.11 EGR34497.1 - 0.12 13.1 2.1 0.18 12.5 0.4 2.2 2 1 0 2 2 2 0 Regulator of ribonuclease activity B SIMPL PF04402.14 EGR34498.1 - 2.4e-19 70.6 3.7 2.8e-19 70.4 3.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) DUF484 PF04340.12 EGR34498.1 - 0.0067 16.1 0.1 0.009 15.7 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF484 DIM1 PF02966.16 EGR34498.1 - 0.039 13.7 1.4 0.042 13.6 0.3 1.5 2 0 0 2 2 2 0 Mitosis protein DIM1 SpoIISB_antitox PF14185.6 EGR34498.1 - 0.04 13.8 1.9 0.085 12.7 0.6 2.2 2 1 0 2 2 2 0 Antitoxin SpoIISB, type II toxin-antitoxin system FlaC_arch PF05377.11 EGR34498.1 - 2 8.9 9.2 4.9 7.6 0.8 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) YtxH PF12732.7 EGR34498.1 - 5.8 7.5 7.2 1 9.9 1.2 2.4 2 1 0 2 2 2 0 YtxH-like protein tRNA-synt_2b PF00587.25 EGR34499.1 - 2.7e-38 131.7 0.0 3.9e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.20 EGR34499.1 - 0.13 11.3 1.5 0.27 10.3 1.5 1.6 1 1 0 1 1 1 0 tRNA synthetases class II (D, K and N) MORN PF02493.20 EGR34500.1 - 5.8e-42 139.1 70.9 5.5e-07 29.1 0.5 9.8 10 0 0 10 10 10 9 MORN repeat AAA PF00004.29 EGR34502.1 - 9.8e-07 29.3 0.0 1.6e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EGR34502.1 - 0.0094 16.1 0.0 0.016 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGR34502.1 - 0.13 12.6 0.0 0.73 10.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain M64_N PF16217.5 EGR34503.1 - 0.0038 16.8 1.8 0.0051 16.4 0.0 2.1 2 0 0 2 2 2 1 Peptidase M64 N-terminus IQ PF00612.27 EGR34503.1 - 0.029 14.1 0.2 0.38 10.7 0.0 2.5 2 0 0 2 2 2 0 IQ calmodulin-binding motif Glycos_transf_1 PF00534.20 EGR34504.1 - 5.9e-17 61.7 0.0 1.2e-16 60.7 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGR34504.1 - 1e-06 28.8 0.0 1.5e-06 28.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EGR34504.1 - 1.5e-05 25.4 0.0 1.9e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EGR34504.1 - 0.0015 18.9 0.0 0.002 18.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Sugar_tr PF00083.24 EGR34505.1 - 1.6e-21 76.7 27.2 2.2e-21 76.2 27.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGR34505.1 - 1e-15 57.5 29.4 6.6e-10 38.4 12.9 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Pkinase PF00069.25 EGR34506.1 - 1.5e-72 244.1 0.2 2.1e-72 243.7 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34506.1 - 5.4e-39 134.0 0.2 9.8e-39 133.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR34506.1 - 0.0044 16.0 0.3 0.0044 16.0 0.3 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EGR34506.1 - 0.0047 16.3 0.0 0.016 14.6 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR34506.1 - 0.0055 15.5 0.0 0.0085 14.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGR34506.1 - 0.0071 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Prenyltransf PF01255.19 EGR34506.1 - 0.043 13.3 0.1 0.083 12.4 0.1 1.4 1 0 0 1 1 1 0 Putative undecaprenyl diphosphate synthase KRAB PF01352.27 EGR34506.1 - 0.072 12.7 0.1 2.9 7.6 0.1 2.7 2 0 0 2 2 2 0 KRAB box Thioredoxin_8 PF13905.6 EGR34507.1 - 2.2e-12 47.1 0.0 2.2e-12 47.1 0.0 3.8 4 0 0 4 4 4 1 Thioredoxin-like Thioredoxin PF00085.20 EGR34507.1 - 1.1e-08 35.0 0.2 3.5e-07 30.2 0.1 2.9 1 1 1 2 2 2 1 Thioredoxin AhpC-TSA PF00578.21 EGR34507.1 - 2.6e-08 33.8 0.8 3.4e-07 30.2 0.0 2.7 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 EGR34507.1 - 1.5e-07 31.3 0.1 4e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Redoxin Thioredoxin_2 PF13098.6 EGR34507.1 - 0.00013 22.4 0.5 0.0028 18.1 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin-like domain YnfE PF17452.2 EGR34507.1 - 0.064 13.6 4.6 5.6 7.3 1.6 3.2 2 0 0 2 2 2 0 Uncharacterized YnfE-like DZR PF12773.7 EGR34507.1 - 0.66 10.1 12.2 0.088 12.8 1.2 3.4 3 1 0 3 3 3 0 Double zinc ribbon Vps39_2 PF10367.9 EGR34507.1 - 1.3 9.5 8.2 0.097 13.1 0.7 2.9 2 2 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 Hydrolase_4 PF12146.8 EGR34508.1 - 5e-12 45.6 0.5 1.3e-11 44.3 0.0 1.9 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR34508.1 - 4.2e-10 39.7 0.0 4.2e-10 39.7 0.0 3.1 3 1 0 3 3 3 1 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 EGR34508.1 - 7.3e-06 25.8 0.0 7.3e-06 25.8 0.0 3.2 2 1 1 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 EGR34508.1 - 0.00015 21.3 0.0 0.00015 21.3 0.0 2.6 2 2 1 3 3 3 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 EGR34508.1 - 0.028 15.0 0.0 0.037 14.6 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase family Esterase PF00756.20 EGR34508.1 - 0.62 9.6 14.2 2.2 7.8 9.8 3.2 1 1 1 2 2 2 0 Putative esterase PPPI_inhib PF14895.6 EGR34509.1 - 0.00013 21.3 1.3 0.00014 21.1 1.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 1 inhibitor Ribosomal_L3 PF00297.22 EGR34509.1 - 0.066 12.2 0.9 0.074 12.0 0.9 1.0 1 0 0 1 1 1 0 Ribosomal protein L3 MORN PF02493.20 EGR34510.1 - 2.4e-50 165.5 79.3 6.5e-07 28.9 1.7 10.2 10 0 0 10 10 10 9 MORN repeat CDC45 PF02724.14 EGR34510.1 - 5.6 5.1 12.5 7.6 4.7 12.5 1.1 1 0 0 1 1 1 0 CDC45-like protein ALMT PF11744.8 EGR34510.1 - 6.5 5.5 5.8 8.4 5.1 5.8 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Presenilin PF01080.17 EGR34510.1 - 8.2 5.1 6.4 11 4.7 6.4 1.1 1 0 0 1 1 1 0 Presenilin PP2C PF00481.21 EGR34512.1 - 4.2e-70 236.3 0.1 4.8e-70 236.1 0.1 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.25 EGR34513.1 - 1.1e-48 166.0 1.4 1.3e-48 165.7 1.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34513.1 - 2.2e-33 115.6 0.4 2.7e-33 115.3 0.4 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR34513.1 - 1.3e-06 27.4 0.1 1.9e-06 26.9 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGR34513.1 - 2.8e-05 23.2 1.0 0.00015 20.8 1.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain ABC1 PF03109.16 EGR34513.1 - 0.0031 17.7 0.0 0.0055 16.9 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Seadorna_VP7 PF07387.11 EGR34513.1 - 0.024 13.7 0.2 0.035 13.1 0.2 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kinase-like PF14531.6 EGR34513.1 - 0.038 13.3 0.0 0.21 10.9 0.0 1.9 2 0 0 2 2 2 0 Kinase-like Abi_2 PF07751.11 EGR34513.1 - 0.055 13.7 0.2 0.14 12.4 0.1 1.7 1 1 1 2 2 2 0 Abi-like protein DUF3267 PF11667.8 EGR34513.1 - 0.18 12.1 0.7 7.1 7.0 0.2 2.2 2 0 0 2 2 2 0 Putative zincin peptidase HSP70 PF00012.20 EGR34515.1 - 1.2e-56 192.2 23.0 1.2e-56 192.2 23.0 3.2 2 1 0 2 2 2 1 Hsp70 protein Pkinase PF00069.25 EGR34515.1 - 5.9e-47 160.3 0.4 5.9e-47 160.3 0.4 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34515.1 - 4.1e-29 101.7 0.2 9.3e-29 100.5 0.2 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase MreB_Mbl PF06723.13 EGR34515.1 - 0.00011 21.2 0.1 0.0038 16.1 0.1 2.3 2 0 0 2 2 2 1 MreB/Mbl protein DUF5308 PF17233.2 EGR34515.1 - 3.2 8.0 6.7 8.5 6.6 6.7 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5308) UBA PF00627.31 EGR34517.1 - 0.055 13.4 0.2 0.11 12.5 0.2 1.5 1 0 0 1 1 1 0 UBA/TS-N domain Herpes_U26 PF07402.11 EGR34517.1 - 0.085 12.4 7.4 0.11 12.1 7.4 1.1 1 0 0 1 1 1 0 Human herpesvirus U26 protein CW_7 PF08230.11 EGR34518.1 - 0.88 9.4 3.9 91 2.9 0.1 3.3 3 0 0 3 3 3 0 CW_7 repeat Senescence PF06911.12 EGR34519.1 - 6.1e-18 65.8 2.8 8.1e-18 65.4 2.8 1.1 1 0 0 1 1 1 1 Senescence-associated protein Transcrip_act PF04949.13 EGR34519.1 - 0.013 15.4 0.1 0.024 14.5 0.1 1.4 1 0 0 1 1 1 0 Transcriptional activator Phasin PF05597.11 EGR34519.1 - 0.019 14.9 1.9 0.029 14.4 1.1 1.7 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) FHA_2 PF17913.1 EGR34519.1 - 0.15 12.3 2.2 0.32 11.2 0.7 2.3 2 0 0 2 2 2 0 FHA domain CCER1 PF15482.6 EGR34520.1 - 0.0034 17.3 1.5 0.01 15.7 0.0 1.9 2 0 0 2 2 2 1 Coiled-coil domain-containing glutamate-rich protein family 1 CRM1_C PF08767.11 EGR34521.1 - 5.2e-73 246.0 17.8 5.2e-73 246.0 17.8 4.4 4 0 0 4 4 4 2 CRM1 C terminal Xpo1 PF08389.12 EGR34521.1 - 1.4e-28 99.8 7.2 1.4e-28 99.8 7.2 5.9 4 1 1 6 6 6 1 Exportin 1-like protein CRM1_repeat_3 PF18787.1 EGR34521.1 - 5e-25 87.4 2.8 2.9e-24 84.9 1.3 3.2 3 0 0 3 3 3 1 CRM1 / Exportin repeat 3 CRM1_repeat_2 PF18784.1 EGR34521.1 - 1.4e-24 85.5 1.2 6.1e-24 83.4 0.4 2.6 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat PF18777.1 EGR34521.1 - 2.3e-14 52.6 0.2 6.3e-14 51.2 0.2 1.8 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EGR34521.1 - 1.5e-05 24.8 2.9 1.5e-05 24.8 2.9 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF818 PF05677.12 EGR34522.1 - 1.5e-08 34.0 0.1 3e-08 33.0 0.1 1.3 1 1 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Hydrolase_4 PF12146.8 EGR34522.1 - 1.8e-06 27.4 0.0 2.8e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR34522.1 - 6.5e-06 26.0 0.1 1.1e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGR34522.1 - 0.0012 19.5 0.0 0.0015 19.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGR34522.1 - 0.0013 18.2 0.1 0.0041 16.6 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EGR34522.1 - 0.0055 16.3 0.0 0.0095 15.6 0.0 1.3 1 1 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 EGR34522.1 - 0.022 14.4 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative esterase DUF915 PF06028.11 EGR34522.1 - 0.16 11.2 0.6 0.63 9.3 0.1 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) ABC_tran PF00005.27 EGR34523.1 - 2e-29 102.8 0.7 3.1e-29 102.3 0.7 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGR34523.1 - 2.4e-08 34.2 0.6 0.00019 21.4 0.0 2.1 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGR34523.1 - 0.001 18.9 1.1 0.001 18.9 1.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 EGR34523.1 - 0.0039 16.6 0.4 0.28 10.6 0.4 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SRP54 PF00448.22 EGR34523.1 - 0.0041 16.8 0.0 0.0083 15.8 0.0 1.5 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 EGR34523.1 - 0.005 15.9 0.1 0.0085 15.2 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein RsgA_GTPase PF03193.16 EGR34523.1 - 0.0057 16.6 0.3 0.023 14.6 0.1 2.0 2 0 0 2 2 2 1 RsgA GTPase AAA_14 PF13173.6 EGR34523.1 - 0.0072 16.4 0.1 0.93 9.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_13 PF13166.6 EGR34523.1 - 0.012 14.3 2.4 0.087 11.5 1.0 2.0 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.13 EGR34523.1 - 0.016 14.4 0.4 0.024 13.8 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Mg_chelatase PF01078.21 EGR34523.1 - 0.02 14.3 0.2 4 6.7 0.0 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 EGR34523.1 - 0.022 15.3 6.4 0.056 13.9 6.4 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGR34523.1 - 0.038 13.7 0.0 0.078 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rad17 PF03215.15 EGR34523.1 - 0.051 13.5 0.5 0.14 12.1 0.3 1.7 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_22 PF13401.6 EGR34523.1 - 0.064 13.5 0.4 0.29 11.4 0.3 2.0 1 1 1 2 2 2 0 AAA domain CbiA PF01656.23 EGR34523.1 - 0.1 12.6 0.2 0.16 12.0 0.2 1.4 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain SbcCD_C PF13558.6 EGR34523.1 - 0.11 12.8 0.0 1.2 9.5 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_29 PF13555.6 EGR34523.1 - 0.13 12.1 0.5 0.27 11.0 0.2 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EGR34523.1 - 0.15 12.4 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EGR34524.1 - 9e-25 87.8 0.0 4e-24 85.7 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EGR34524.1 - 8.1e-11 42.3 0.6 1.3e-06 28.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGR34524.1 - 0.0016 19.0 0.8 0.0016 19.0 0.8 2.8 2 1 0 2 2 2 1 AAA domain SMC_N PF02463.19 EGR34524.1 - 0.002 17.6 2.8 1.1 8.6 0.1 2.7 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGR34524.1 - 0.0053 16.5 16.3 0.01 15.6 0.0 3.3 2 1 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EGR34524.1 - 0.038 13.7 0.2 0.084 12.6 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4162 PF13732.6 EGR34524.1 - 0.19 12.5 3.9 0.29 11.9 1.7 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4162) PepX_C PF08530.10 EGR34527.1 - 4.7e-36 124.8 0.0 6.8e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain Peptidase_S15 PF02129.18 EGR34527.1 - 8.3e-29 101.0 0.0 1.2e-28 100.5 0.0 1.2 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EGR34527.1 - 0.029 14.0 0.0 0.15 11.6 0.0 2.0 1 1 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGR34527.1 - 0.038 13.4 0.1 3.6 7.0 0.0 2.6 2 1 1 3 3 3 0 Prolyl oligopeptidase family YlqD PF11068.8 EGR34528.1 - 4.7 7.6 12.2 7.6 6.9 12.2 1.3 1 1 0 1 1 1 0 YlqD protein Acyltransferase PF01553.21 EGR34529.1 - 0.0094 15.6 0.1 0.02 14.5 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase Pkinase PF00069.25 EGR34530.1 - 1.4e-69 234.4 0.2 3e-69 233.3 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34530.1 - 1.4e-41 142.5 0.1 2.4e-41 141.7 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR34530.1 - 6.8e-07 28.4 0.1 1.6e-06 27.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase FRB_dom PF08771.11 EGR34530.1 - 0.0069 16.8 1.5 0.031 14.7 1.5 2.2 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain APH PF01636.23 EGR34530.1 - 0.078 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family XRN_N PF03159.18 EGR34531.1 - 3.6e-94 314.7 0.0 4.1e-94 314.5 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DUF1494 PF07379.11 EGR34532.1 - 0.032 14.1 18.3 1 9.2 1.6 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1494) ESPR PF13018.6 EGR34532.1 - 0.44 10.4 3.2 93 2.9 0.1 3.6 3 0 0 3 3 3 0 Extended Signal Peptide of Type V secretion system SWM_repeat PF13753.6 EGR34532.1 - 0.99 9.6 3.6 76 3.6 0.1 3.1 3 0 0 3 3 3 0 Putative flagellar system-associated repeat WD40 PF00400.32 EGR34536.1 - 4e-17 62.3 15.8 0.00084 20.1 0.0 8.8 9 1 0 9 9 9 5 WD domain, G-beta repeat HELP PF03451.14 EGR34536.1 - 5e-17 61.5 0.6 5.4e-16 58.2 0.6 2.3 1 1 0 1 1 1 1 HELP motif ANAPC4_WD40 PF12894.7 EGR34536.1 - 6.9e-12 45.5 2.4 0.0001 22.5 0.0 6.4 4 2 3 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 EGR34536.1 - 0.00029 20.2 0.0 0.037 13.3 0.0 2.3 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller eIF2A PF08662.11 EGR34536.1 - 0.011 15.6 0.3 1.6 8.6 0.1 3.3 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EGR34536.1 - 0.19 11.7 0.9 7.4 6.6 0.0 3.6 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat ADH_N_2 PF16884.5 EGR34537.1 - 0.07 13.0 0.0 0.095 12.6 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase Prefoldin_2 PF01920.20 EGR34538.1 - 1.8e-14 53.6 3.0 2.1e-14 53.4 3.0 1.1 1 0 0 1 1 1 1 Prefoldin subunit NDK PF00334.19 EGR34539.1 - 0.00015 21.8 0.6 0.03 14.3 0.1 3.3 2 1 1 3 3 3 2 Nucleoside diphosphate kinase MMR1 PF08505.10 EGR34539.1 - 1.1 9.5 10.2 7.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein EDR1 PF14381.6 EGR34539.1 - 2.3 7.9 7.1 0.77 9.4 0.5 2.6 2 0 0 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 MORN PF02493.20 EGR34540.1 - 4.1e-53 174.2 62.2 1.4e-07 31.0 1.5 9.4 9 0 0 9 9 9 9 MORN repeat Tudor_2 PF18104.1 EGR34540.1 - 0.063 13.0 0.1 0.063 13.0 0.1 5.0 5 1 1 6 6 6 0 Jumonji domain-containing protein 2A Tudor domain BsuPI PF12690.7 EGR34540.1 - 0.25 11.4 2.8 0.32 11.1 0.1 2.7 3 1 1 4 4 4 0 Intracellular proteinase inhibitor DUF1107 PF06526.12 EGR34540.1 - 0.38 10.7 1.9 14 5.7 0.1 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF1107) MatE PF01554.18 EGR34541.1 - 2.2e-11 43.6 21.3 2.6e-07 30.4 3.3 2.4 2 0 0 2 2 2 2 MatE NAP PF00956.18 EGR34542.1 - 1.8e-57 194.6 18.3 3e-57 193.9 18.3 1.3 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) DUF1462 PF07315.11 EGR34543.1 - 0.69 10.2 5.1 0.89 9.9 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1462) DUF4473 PF14747.6 EGR34544.1 - 0.11 13.1 4.3 4.3 8.0 2.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) DUF16 PF01519.16 EGR34544.1 - 0.14 12.6 0.1 0.14 12.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF16 Lebercilin PF15619.6 EGR34544.1 - 0.52 9.9 10.1 0.05 13.3 2.3 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease RNA_capsid PF03035.14 EGR34545.1 - 5.4 7.0 10.3 0.15 12.1 3.0 1.9 2 0 0 2 2 2 0 Calicivirus putative RNA polymerase/capsid protein MORN PF02493.20 EGR34546.1 - 2.4e-41 137.2 59.1 1.8e-07 30.6 5.4 9.4 9 0 0 9 9 9 9 MORN repeat Tudor_2 PF18104.1 EGR34546.1 - 1.7 8.4 7.9 47 3.8 0.2 4.1 3 0 0 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain Pkinase PF00069.25 EGR34548.1 - 7.7e-49 166.4 0.3 9.7e-49 166.1 0.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34548.1 - 3.1e-31 108.6 0.1 4e-31 108.2 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR34548.1 - 5.3e-05 22.2 0.0 8.5e-05 21.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGR34548.1 - 0.00063 19.1 0.6 0.0022 17.4 0.1 2.1 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGR34548.1 - 0.0054 15.7 0.8 0.0065 15.4 0.0 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kdo PF06293.14 EGR34548.1 - 0.024 14.0 0.1 0.044 13.1 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ZYG-11_interact PF05884.12 EGR34549.1 - 1.1 8.6 2.6 1.3 8.4 2.6 1.1 1 0 0 1 1 1 0 Interactor of ZYG-11 G_path_suppress PF15991.5 EGR34550.1 - 0.053 13.6 0.1 0.091 12.9 0.1 1.3 1 0 0 1 1 1 0 G-protein pathway suppressor zf-TFIIIC PF12660.7 EGR34550.1 - 0.09 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex TPR_2 PF07719.17 EGR34551.1 - 9.4e-09 34.7 5.1 1 9.6 0.8 5.3 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGR34551.1 - 2.2e-05 24.1 9.5 2.1 8.3 0.5 4.7 4 0 0 4 4 4 3 Tetratricopeptide repeat DUF3808 PF10300.9 EGR34551.1 - 0.00022 20.1 3.9 0.0053 15.5 0.2 2.2 2 1 0 2 2 2 2 Protein of unknown function (DUF3808) TMEM154 PF15102.6 EGR34551.1 - 0.028 14.3 13.5 0.065 13.1 13.5 1.5 1 0 0 1 1 1 0 TMEM154 protein family Shisa PF13908.6 EGR34551.1 - 0.49 10.6 5.2 0.78 10.0 5.2 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator T2SSF PF00482.23 EGR34551.1 - 0.65 10.0 2.5 1.5 8.8 2.5 1.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F TPR_21 PF09976.9 EGR34551.1 - 4.3 7.0 10.7 0.095 12.4 0.5 3.1 1 1 2 4 4 4 0 Tetratricopeptide repeat-like domain PDR_CDR PF06422.12 EGR34551.1 - 6 6.8 10.7 1.6 8.7 3.7 2.4 1 1 1 2 2 2 0 CDR ABC transporter TPR_2 PF07719.17 EGR34552.1 - 8.3e-08 31.8 8.5 0.06 13.5 0.1 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGR34552.1 - 4.1e-07 29.5 15.3 0.33 10.9 1.3 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGR34552.1 - 0.0021 18.1 11.4 0.36 11.2 0.0 5.9 6 0 0 6 6 6 1 Tetratricopeptide repeat BTAD PF03704.17 EGR34552.1 - 0.015 15.7 0.0 0.023 15.1 0.0 1.2 1 0 0 1 1 1 0 Bacterial transcriptional activator domain TPR_17 PF13431.6 EGR34552.1 - 0.072 13.5 6.1 32 5.2 0.2 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGR34552.1 - 0.11 12.3 8.0 1.2 8.9 0.1 4.6 3 2 2 5 5 5 0 TPR repeat MIT PF04212.18 EGR34552.1 - 0.11 12.5 4.8 1 9.4 0.1 3.9 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 EGR34552.1 - 0.17 12.4 2.0 3.4 8.3 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGR34552.1 - 0.18 11.3 3.1 8.7 5.9 0.4 3.3 2 1 1 3 3 3 0 SHNi-TPR ANAPC3 PF12895.7 EGR34552.1 - 0.51 10.6 9.6 0.37 11.0 0.3 3.5 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 FN3_7 PF18447.1 EGR34552.1 - 1.1 9.6 10.2 0.17 12.2 0.4 3.2 2 1 1 3 3 3 0 Fibronectin type III domain Mito_carr PF00153.27 EGR34554.1 - 9.4e-48 160.1 2.0 3.4e-21 75.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF3021 PF11457.8 EGR34554.1 - 0.27 11.6 3.4 0.26 11.6 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3021) Pkinase PF00069.25 EGR34555.1 - 1.7e-64 217.8 0.1 2.9e-64 217.0 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34555.1 - 8.7e-29 100.6 0.0 1.3e-28 100.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR34555.1 - 1.7e-08 34.1 0.1 3.3e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGR34555.1 - 1.3e-05 25.0 3.1 0.005 16.5 0.0 3.2 2 1 1 3 3 3 2 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 EGR34555.1 - 1.4e-05 24.5 0.0 3e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.19 EGR34555.1 - 0.00042 20.1 0.0 0.00083 19.1 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 DnaG_DnaB_bind PF08278.11 EGR34555.1 - 0.0063 17.1 0.0 1.2 9.7 0.0 2.4 2 0 0 2 2 2 1 DNA primase DnaG DnaB-binding zf-CHC2 PF01807.20 EGR34555.1 - 0.0083 15.9 0.3 3 7.7 0.0 2.8 2 0 0 2 2 2 2 CHC2 zinc finger APH PF01636.23 EGR34555.1 - 0.042 13.8 0.0 0.071 13.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family MORN PF02493.20 EGR34556.1 - 3.2e-15 55.0 24.6 2.3e-05 24.0 2.8 4.0 5 0 0 5 5 5 3 MORN repeat DUF3862 PF12978.7 EGR34556.1 - 0.0015 18.3 0.3 0.0019 18.0 0.3 1.1 1 0 0 1 1 1 1 Domain of Unknown Function with PDB structure (DUF3862) HEAT PF02985.22 EGR34557.1 - 3.1e-39 129.6 13.5 0.00098 19.2 0.0 13.6 14 0 0 14 14 14 8 HEAT repeat HEAT_2 PF13646.6 EGR34557.1 - 8.2e-32 109.5 0.0 2.3e-05 24.7 0.0 7.7 2 2 4 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.7 EGR34557.1 - 2e-15 57.1 12.3 0.025 15.2 0.2 7.1 3 1 3 7 7 7 6 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EGR34557.1 - 1.9e-13 49.8 24.9 8e-07 28.0 5.9 3.9 1 1 1 3 3 3 3 Adaptin N terminal region Cnd1 PF12717.7 EGR34557.1 - 2.8e-13 50.2 23.2 0.0017 18.4 0.9 6.6 1 1 6 7 7 7 5 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGR34557.1 - 5.1e-12 45.8 8.4 0.0034 17.0 0.4 5.7 2 1 4 6 6 6 5 CLASP N terminal HEAT_EZ PF13513.6 EGR34557.1 - 2.7e-08 34.2 0.3 6.4 7.4 0.0 7.5 8 1 0 8 8 8 1 HEAT-like repeat RTP1_C1 PF10363.9 EGR34557.1 - 1.3e-05 25.4 12.7 1.4 9.1 1.1 5.9 3 3 2 5 5 5 3 Required for nuclear transport of RNA pol II C-terminus 1 DUF4042 PF13251.6 EGR34557.1 - 2.1e-05 24.3 5.4 5.3 6.7 0.2 6.1 2 2 1 5 5 5 1 Domain of unknown function (DUF4042) DNA_alkylation PF08713.11 EGR34557.1 - 0.00068 19.4 1.7 10 5.8 0.3 4.7 2 1 4 6 6 6 1 DNA alkylation repair enzyme DUF61 PF01886.16 EGR34557.1 - 0.0071 16.4 11.6 0.093 12.8 1.5 4.4 3 1 2 5 5 5 2 Protein of unknown function DUF61 DUF3730 PF12530.8 EGR34557.1 - 0.01 15.4 4.5 3.9 7.0 4.5 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3730) ATP-synt_ab PF00006.25 EGR34557.1 - 0.1 12.2 0.0 0.21 11.2 0.0 1.6 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain TPR_22 PF18833.1 EGR34557.1 - 1.9 8.7 10.3 9.2 6.5 0.1 4.4 4 1 0 4 4 4 0 Tetratricopeptide repeat Ion_trans_2 PF07885.16 EGR34558.1 - 8.1e-14 51.4 5.1 8.1e-14 51.4 5.1 2.5 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 EGR34558.1 - 1e-12 47.9 0.0 1.8e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 EGR34558.1 - 3e-10 39.8 26.6 3e-10 39.8 26.6 2.0 2 0 0 2 2 2 1 Ion transport protein VPS13_C PF16909.5 EGR34560.1 - 6.7e-48 162.8 5.7 6.7e-48 162.8 5.7 3.9 2 1 2 4 4 4 1 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 EGR34560.1 - 0.003 17.9 0.0 0.011 16.0 0.0 1.9 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Glu-tRNAGln PF02686.15 EGR34560.1 - 1.8 8.9 4.1 4 7.8 0.1 3.3 3 1 1 4 4 4 0 Glu-tRNAGln amidotransferase C subunit PRC2_HTH_1 PF18118.1 EGR34560.1 - 2.6 8.9 11.4 0.24 12.2 4.8 2.5 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Cytochrom_C PF00034.21 EGR34562.1 - 3.5e-05 24.9 4.2 3.7e-05 24.8 0.0 2.7 2 2 0 2 2 2 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EGR34562.1 - 0.00038 20.7 0.1 0.0016 18.7 0.1 2.1 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III MeaB PF03308.16 EGR34562.1 - 0.099 11.6 1.9 0.14 11.1 1.9 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Haem_bd PF14376.6 EGR34562.1 - 4.5 7.2 11.9 5.6 6.9 0.8 2.7 1 1 1 2 2 2 0 Haem-binding domain SPT2 PF08243.11 EGR34563.1 - 2.3e-18 66.8 34.4 2.9e-18 66.4 22.1 2.1 2 0 0 2 2 2 2 SPT2 chromatin protein PBP1_TM PF14812.6 EGR34563.1 - 8.1 6.9 24.4 0.71 10.3 12.6 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PP2C PF00481.21 EGR34564.1 - 1.9e-45 155.5 0.0 1.9e-45 155.5 0.0 1.8 3 0 0 3 3 3 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGR34564.1 - 0.094 12.3 0.0 0.26 10.9 0.0 1.8 2 0 0 2 2 2 0 Protein phosphatase 2C DUF4529 PF15032.6 EGR34564.1 - 3.5 6.7 6.4 0.29 10.2 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4529) DUF676 PF05057.14 EGR34565.1 - 2e-26 92.9 3.5 3.3e-26 92.2 3.5 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGR34565.1 - 4.2e-05 23.5 0.3 6.2e-05 23.0 0.2 1.4 1 1 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 EGR34565.1 - 0.0017 18.1 0.0 0.002 17.9 0.0 1.3 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 EGR34565.1 - 0.2 10.9 0.0 0.28 10.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 C2 PF00168.30 EGR34566.1 - 3.6e-31 107.5 2.3 3.3e-08 33.7 0.0 5.4 5 0 0 5 5 5 4 C2 domain Ferlin_C PF16165.5 EGR34566.1 - 0.00056 19.9 0.0 0.00056 19.9 0.0 3.7 5 0 0 5 5 5 1 Ferlin C-terminus ACBP PF00887.19 EGR34567.1 - 8.7e-25 86.8 0.3 9.7e-25 86.6 0.3 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein PFK PF00365.20 EGR34569.1 - 1.1e-06 28.2 0.0 6.7e-06 25.6 0.0 1.9 2 0 0 2 2 2 1 Phosphofructokinase OAD_gamma PF04277.13 EGR34570.1 - 0.043 14.4 1.4 0.12 13.0 1.4 1.8 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain UPF0239 PF06783.11 EGR34570.1 - 0.078 13.2 5.1 0.2 11.9 5.1 1.7 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) Thioredoxin_8 PF13905.6 EGR34571.1 - 6.7e-27 93.7 0.1 6.7e-27 93.7 0.1 2.3 3 0 0 3 3 3 1 Thioredoxin-like Zn_ribbon_17 PF17120.5 EGR34571.1 - 3.1e-08 33.1 1.0 6.1e-08 32.2 1.0 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type WD40 PF00400.32 EGR34571.1 - 4e-05 24.3 1.0 0.00084 20.1 0.2 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat Thioredoxin PF00085.20 EGR34571.1 - 0.00072 19.5 3.0 0.0019 18.2 0.1 2.7 2 1 1 3 3 3 1 Thioredoxin BBS2_Mid PF14783.6 EGR34571.1 - 0.0018 18.3 0.0 0.0056 16.7 0.0 1.8 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 EGR34571.1 - 0.0029 16.3 5.8 0.019 13.6 0.1 2.6 3 0 0 3 3 3 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGR34571.1 - 0.0047 17.2 0.6 0.12 12.7 0.2 2.9 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain DUF1198 PF06711.11 EGR34571.1 - 0.25 11.4 2.2 11 6.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1198) zf-rbx1 PF12678.7 EGR34571.1 - 2.2 8.6 12.4 0.063 13.6 4.8 2.4 2 1 0 2 2 2 0 RING-H2 zinc finger domain MFS_1 PF07690.16 EGR34572.1 - 4.5e-23 81.8 35.7 4.9e-22 78.3 28.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGR34572.1 - 2e-13 49.7 9.7 2e-13 49.7 9.7 2.7 3 0 0 3 3 3 2 MFS/sugar transport protein Amidase PF01425.21 EGR34573.1 - 1.1e-93 314.7 0.0 1.3e-93 314.5 0.0 1.0 1 0 0 1 1 1 1 Amidase TOM6p PF15184.6 EGR34574.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial import receptor subunit TOM6 homolog Syja_N PF02383.18 EGR34576.1 - 3.1e-63 214.0 7.7 3.1e-63 214.0 7.7 1.8 2 0 0 2 2 2 1 SacI homology domain Ribonuc_L-PSP PF01042.21 EGR34577.1 - 3.3e-37 127.2 0.2 4.1e-37 126.9 0.2 1.1 1 0 0 1 1 1 1 Endoribonuclease L-PSP Eclosion PF04736.12 EGR34577.1 - 0.05 13.3 0.0 0.094 12.4 0.0 1.4 1 0 0 1 1 1 0 Eclosion hormone DUF4953 PF16313.5 EGR34577.1 - 0.053 12.7 0.0 0.056 12.7 0.0 1.1 1 0 0 1 1 1 0 Met-zincin Rab3-GTPase_cat PF13890.6 EGR34577.1 - 0.084 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein catalytic subunit GIT1_C PF12205.8 EGR34577.1 - 0.085 13.0 0.0 0.16 12.1 0.0 1.5 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term Pribosyltran PF00156.27 EGR34578.1 - 2.3e-11 43.5 0.0 2.8e-11 43.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGR34578.1 - 0.03 13.8 0.0 0.037 13.5 0.0 1.2 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 EGR34578.1 - 0.094 12.2 0.1 0.14 11.7 0.1 1.4 1 1 0 1 1 1 0 Phosphoribosyl transferase adh_short PF00106.25 EGR34579.1 - 1.7e-08 34.2 0.0 1.9e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGR34579.1 - 0.0039 17.1 0.0 0.0044 16.9 0.0 1.1 1 0 0 1 1 1 1 KR domain HA70_C PF17993.1 EGR34579.1 - 0.012 15.6 0.2 0.012 15.6 0.2 1.1 1 0 0 1 1 1 0 Haemagglutinin 70 C-terminal domain adh_short_C2 PF13561.6 EGR34579.1 - 0.031 13.9 0.0 0.037 13.6 0.0 1.1 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase TPR_12 PF13424.6 EGR34581.1 - 1.8e-18 66.6 0.2 1.2e-08 35.1 0.0 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat eIF3_p135 PF12807.7 EGR34581.1 - 6.8e-15 55.5 3.2 6.8e-15 55.5 3.2 2.7 2 1 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 TPR_1 PF00515.28 EGR34581.1 - 6.9e-09 35.2 6.6 0.035 13.9 0.2 4.2 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGR34581.1 - 1.5e-06 27.8 1.7 0.076 13.2 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGR34581.1 - 0.00045 20.2 8.3 1.7 9.1 0.7 4.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGR34581.1 - 0.021 14.7 0.0 5.5 7.0 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGR34581.1 - 0.022 14.4 3.1 5.5 6.8 0.2 3.5 3 0 0 3 3 3 0 TPR repeat Orthopox_F14 PF06076.12 EGR34581.1 - 0.033 14.5 0.9 0.1 12.9 0.7 1.9 2 0 0 2 2 1 0 Orthopoxvirus F14 protein TPR_3 PF07720.12 EGR34581.1 - 0.038 14.0 1.5 0.15 12.0 1.5 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EGR34581.1 - 0.045 13.1 0.3 0.17 11.2 0.1 2.0 1 1 0 2 2 2 0 MalT-like TPR region TPR_7 PF13176.6 EGR34581.1 - 0.1 12.6 0.0 1.2 9.3 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat AAA_6 PF12774.7 EGR34582.1 - 1.1e-135 451.8 2.4 1.5e-134 448.1 0.1 3.6 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGR34582.1 - 1.2e-106 357.2 11.1 1.2e-106 357.2 11.1 5.3 4 1 1 5 5 3 1 Dynein heavy chain, N-terminal region 2 DHC_N1 PF08385.12 EGR34582.1 - 3.3e-97 326.4 40.6 3.3e-97 326.4 40.6 4.0 3 1 1 4 4 4 1 Dynein heavy chain, N-terminal region 1 AAA_7 PF12775.7 EGR34582.1 - 1.2e-39 135.7 0.8 4.5e-35 120.8 0.0 4.3 4 0 0 4 4 4 2 P-loop containing dynein motor region AAA_5 PF07728.14 EGR34582.1 - 2.6e-25 89.0 0.0 3.2e-13 49.9 0.0 4.8 3 1 0 3 3 3 3 AAA domain (dynein-related subfamily) Dynein_AAA_lid PF17852.1 EGR34582.1 - 2.6e-17 63.1 0.0 1.4e-16 60.7 0.0 2.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA PF00004.29 EGR34582.1 - 2e-13 50.9 0.0 1.2e-05 25.7 0.0 5.1 5 0 0 5 5 4 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGR34582.1 - 2.2e-11 44.2 0.1 0.00081 19.7 0.0 5.8 5 0 0 5 5 5 2 AAA domain AAA_16 PF13191.6 EGR34582.1 - 7.8e-07 29.6 0.0 0.065 13.6 0.0 5.0 5 0 0 5 5 4 1 AAA ATPase domain AAA_33 PF13671.6 EGR34582.1 - 8e-07 29.3 0.0 0.3 11.2 0.0 3.7 3 0 0 3 3 3 2 AAA domain AAA_18 PF13238.6 EGR34582.1 - 8.5e-05 23.1 0.7 8.6 6.9 0.0 5.2 4 0 0 4 4 4 0 AAA domain T2SSE PF00437.20 EGR34582.1 - 0.00012 21.3 0.0 0.012 14.7 0.0 2.7 2 0 0 2 2 2 1 Type II/IV secretion system protein IstB_IS21 PF01695.17 EGR34582.1 - 0.00019 21.2 0.1 0.36 10.5 0.0 3.8 4 0 0 4 4 4 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EGR34582.1 - 0.00024 21.5 0.4 4.3 7.8 0.0 5.1 4 0 0 4 4 4 1 RNA helicase Mg_chelatase PF01078.21 EGR34582.1 - 0.00028 20.3 0.7 0.6 9.4 0.0 3.1 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_lid_1 PF17857.1 EGR34582.1 - 0.0014 18.8 1.1 0.0096 16.1 0.0 3.1 3 0 0 3 3 3 1 AAA+ lid domain AAA_19 PF13245.6 EGR34582.1 - 0.0042 17.4 0.0 0.16 12.3 0.0 3.2 3 0 0 3 3 2 1 AAA domain YscO PF07321.12 EGR34582.1 - 0.005 16.8 2.9 1.9 8.4 0.2 3.3 1 1 1 2 2 2 2 Type III secretion protein YscO AAA_30 PF13604.6 EGR34582.1 - 0.0086 15.8 0.0 21 4.8 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 EGR34582.1 - 0.049 13.9 0.1 16 5.7 0.0 3.6 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 EGR34582.1 - 0.079 13.5 2.9 6.6 7.2 0.0 4.8 5 0 0 5 5 4 0 ABC transporter Sigma54_activat PF00158.26 EGR34582.1 - 0.081 12.6 0.0 0.91 9.2 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.6 EGR34582.1 - 0.16 11.6 0.0 1.1 8.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EGR34582.1 - 0.34 10.6 0.0 0.34 10.6 0.0 5.0 5 1 0 5 5 3 0 AAA domain Spectrin PF00435.21 EGR34582.1 - 0.48 10.9 12.6 0.87 10.1 1.1 5.9 5 0 0 5 5 3 0 Spectrin repeat DUF4288 PF14119.6 EGR34582.1 - 3.7 8.0 6.4 3.3 8.2 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4288) Apolipoprotein PF01442.18 EGR34582.1 - 7.8 6.3 8.9 73 3.2 0.1 5.4 5 1 0 5 5 5 0 Apolipoprotein A1/A4/E domain Furin-like_2 PF15913.5 EGR34583.1 - 3e-13 49.9 111.1 1.5e-07 31.6 22.9 5.5 1 1 4 5 5 5 4 Furin-like repeat, cysteine-rich GF_recep_IV PF14843.6 EGR34583.1 - 0.006 16.4 92.2 0.19 11.5 21.7 4.8 1 1 5 6 6 6 5 Growth factor receptor domain IV VSP PF03302.13 EGR34583.1 - 1.3 7.8 71.5 0.11 11.3 39.2 4.6 2 2 2 4 4 4 0 Giardia variant-specific surface protein Hydrolase_6 PF13344.6 EGR34584.1 - 3.1e-15 56.1 0.0 1.4e-14 54.0 0.0 2.1 2 1 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGR34584.1 - 4.3e-13 49.1 0.0 7.3e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 EGR34584.1 - 0.00016 22.1 0.0 0.0023 18.3 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase OTCace PF00185.24 EGR34584.1 - 0.094 12.8 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain PhoPQ_related PF10142.9 EGR34584.1 - 0.11 11.1 0.1 0.44 9.2 0.1 2.0 2 0 0 2 2 2 0 PhoPQ-activated pathogenicity-related protein Eno-Rase_FAD_bd PF07055.12 EGR34585.1 - 0.002 18.5 0.3 0.21 12.0 0.0 3.5 4 0 0 4 4 4 1 Enoyl reductase FAD binding domain CUE PF02845.16 EGR34585.1 - 0.0037 16.9 0.0 0.066 12.9 0.0 2.6 2 0 0 2 2 2 1 CUE domain AAR2 PF05282.11 EGR34586.1 - 2.8e-42 145.4 0.1 3.2e-42 145.2 0.1 1.0 1 0 0 1 1 1 1 AAR2 protein Peptidase_C26 PF07722.13 EGR34587.1 - 1e-18 67.9 0.0 1.6e-18 67.2 0.0 1.3 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 EGR34587.1 - 4.3e-09 36.4 0.0 1.9e-08 34.3 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase class-I TMF_DNA_bd PF12329.8 EGR34588.1 - 0.0059 16.6 9.2 0.0059 16.6 9.2 12.6 4 4 4 11 11 11 5 TATA element modulatory factor 1 DNA binding MORN PF02493.20 EGR34590.1 - 6.5e-34 113.8 42.6 5.6e-10 38.5 4.3 7.1 7 0 0 7 7 7 7 MORN repeat Tudor_2 PF18104.1 EGR34590.1 - 0.42 10.3 5.9 2.9 7.6 1.0 3.6 3 0 0 3 3 3 0 Jumonji domain-containing protein 2A Tudor domain Myotub-related PF06602.14 EGR34591.1 - 4.9e-60 203.3 2.6 5.8e-60 203.1 2.6 1.1 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 EGR34591.1 - 0.035 13.7 0.0 0.074 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EGR34591.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family CoaE PF01121.20 EGR34592.1 - 1.2e-20 74.0 0.0 1.6e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 EGR34592.1 - 0.068 13.7 0.0 0.1 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain Beta-Casp PF10996.8 EGR34593.1 - 6.9e-25 87.5 0.1 2.1e-24 85.9 0.0 1.8 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 EGR34593.1 - 5.7e-22 78.1 0.2 1.2e-21 77.0 0.2 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain RMMBL PF07521.12 EGR34593.1 - 2.5e-13 49.7 0.0 7.9e-13 48.1 0.0 1.8 2 0 0 2 2 2 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 EGR34593.1 - 1.3e-11 44.9 0.0 4.8e-11 43.0 0.0 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGR34593.1 - 1.1e-08 34.8 0.0 1.2e-06 28.2 0.0 2.8 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 EGR34593.1 - 1.3e-06 27.8 1.8 2.5e-06 26.9 1.8 1.4 1 0 0 1 1 1 1 Putative beta-lactamase-like family Lactamase_B_3 PF13483.6 EGR34593.1 - 1.2e-05 25.3 0.0 3.7e-05 23.7 0.0 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain MORN PF02493.20 EGR34595.1 - 6.1e-48 157.9 98.8 4.8e-06 26.2 4.4 13.1 13 0 0 13 13 13 12 MORN repeat SM-ATX PF14438.6 EGR34595.1 - 1.2 9.3 5.0 18 5.6 0.1 3.1 3 0 0 3 3 3 0 Ataxin 2 SM domain Proteasome PF00227.26 EGR34596.1 - 1.7e-08 34.2 0.3 2.7e-07 30.3 0.3 2.1 1 1 0 1 1 1 1 Proteasome subunit RabGAP-TBC PF00566.18 EGR34597.1 - 1.3e-08 34.8 5.4 1.3e-08 34.8 5.4 3.9 4 1 1 5 5 5 1 Rab-GTPase-TBC domain AF2331-like PF14556.6 EGR34597.1 - 0.033 14.8 0.2 0.19 12.3 0.1 2.2 2 0 0 2 2 2 0 AF2331-like PUF PF00806.19 EGR34598.1 - 4.7e-40 133.1 28.1 7.6e-08 31.6 0.8 7.7 7 0 0 7 7 7 7 Pumilio-family RNA binding repeat tRNA_bind PF01588.20 EGR34599.1 - 0.00039 20.5 0.1 0.00059 19.9 0.1 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain Methyltransf_11 PF08241.12 EGR34600.1 - 6.8e-15 55.5 0.0 1.2e-14 54.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGR34600.1 - 2.2e-11 44.3 0.0 6.5e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGR34600.1 - 1e-10 41.6 1.4 2.6e-10 40.3 1.3 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGR34600.1 - 2.6e-06 26.9 0.1 3.5e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGR34600.1 - 9.4e-05 23.1 0.0 0.0002 22.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGR34600.1 - 0.0045 16.9 0.0 0.0073 16.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Patched PF02460.18 EGR34600.1 - 0.016 13.3 1.1 0.021 12.9 1.1 1.2 1 0 0 1 1 1 0 Patched family Pept_tRNA_hydro PF01195.19 EGR34600.1 - 0.05 13.6 0.1 0.084 12.8 0.1 1.4 1 0 0 1 1 1 0 Peptidyl-tRNA hydrolase adh_short PF00106.25 EGR34600.1 - 0.051 13.0 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Snf7 PF03357.21 EGR34601.1 - 0.0025 17.4 29.1 0.0031 17.1 29.1 1.1 1 0 0 1 1 1 1 Snf7 Lipase_GDSL_3 PF14606.6 EGR34601.1 - 0.37 10.9 6.7 0.13 12.4 1.8 2.1 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Glycolytic PF00274.19 EGR34602.1 - 1.5e-161 536.9 0.1 1.7e-161 536.8 0.1 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I Thioredoxin_7 PF13899.6 EGR34602.1 - 0.016 15.3 0.1 27 5.0 0.0 4.0 4 0 0 4 4 4 0 Thioredoxin-like Proteasome PF00227.26 EGR34603.1 - 3.4e-58 196.3 0.0 4.1e-58 196.0 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGR34603.1 - 4.2e-11 42.3 0.1 1.2e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Spy1 PF11357.8 EGR34603.1 - 0.078 13.3 0.1 0.18 12.1 0.1 1.5 2 0 0 2 2 2 0 Cell cycle regulatory protein 3HCDH_N PF02737.18 EGR34604.1 - 3.1e-57 193.4 0.5 3.8e-57 193.1 0.5 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EGR34604.1 - 2.4e-36 124.3 0.0 4.4e-36 123.4 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EGR34604.1 - 0.013 15.7 0.1 0.029 14.5 0.1 1.6 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_Gly3P_dh_N PF01210.23 EGR34604.1 - 0.016 15.2 0.5 0.038 14.0 0.5 1.7 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus BBP1_C PF15272.6 EGR34604.1 - 0.05 13.4 0.2 0.073 12.9 0.2 1.2 1 0 0 1 1 1 0 Spindle pole body component BBP1, C-terminal Sacchrp_dh_NADP PF03435.18 EGR34604.1 - 0.13 12.5 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain DUF3617 PF12276.8 EGR34606.1 - 0.6 10.4 5.0 0.15 12.4 0.7 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF3617) Lactamase_B_6 PF16661.5 EGR34606.1 - 7.6 5.9 9.5 8.2 5.8 1.3 2.7 2 1 1 3 3 3 0 Metallo-beta-lactamase superfamily domain EHN PF06441.12 EGR34606.1 - 8.2 6.9 9.8 16 6.0 6.7 2.6 2 1 0 2 2 2 0 Epoxide hydrolase N terminus Peptidase_S24 PF00717.23 EGR34607.1 - 1.4e-09 37.7 0.1 2.3e-09 37.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 EGR34607.1 - 0.00016 21.4 0.0 0.0015 18.3 0.0 2.0 1 1 1 2 2 2 1 Signal peptidase, peptidase S26 EF-hand_1 PF00036.32 EGR34608.1 - 2.3e-41 136.2 10.4 3.1e-10 38.8 0.8 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGR34608.1 - 1.2e-34 118.6 2.4 4.2e-17 62.3 0.8 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGR34608.1 - 2.7e-32 110.4 10.4 1.4e-15 56.9 0.6 4.1 1 1 3 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EGR34608.1 - 9.2e-30 100.0 5.3 1.3e-09 37.2 0.1 4.4 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGR34608.1 - 1.6e-26 90.6 7.6 2.3e-06 26.8 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EGR34608.1 - 4.1e-16 59.1 0.1 6.4e-09 36.0 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 EGR34608.1 - 3.4e-09 36.6 0.3 0.00034 20.5 0.1 2.2 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGR34608.1 - 1.3e-07 31.9 0.2 0.015 15.6 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EGR34608.1 - 1.3e-06 29.2 0.0 0.0017 19.2 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain UPF0154 PF03672.13 EGR34608.1 - 1.1e-05 25.4 0.0 0.042 13.9 0.0 3.1 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0154) TerB PF05099.13 EGR34608.1 - 0.00017 21.6 0.2 0.078 12.9 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB Dockerin_1 PF00404.18 EGR34608.1 - 0.00061 19.9 3.6 0.13 12.5 0.3 2.8 2 2 0 2 2 2 2 Dockerin type I domain DUF3349 PF11829.8 EGR34608.1 - 0.00075 20.2 0.6 1.2 10.0 0.0 2.9 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) Caleosin PF05042.13 EGR34608.1 - 0.0009 19.2 0.3 0.46 10.4 0.0 3.3 1 1 3 4 4 4 1 Caleosin related protein EFhand_Ca_insen PF08726.10 EGR34608.1 - 0.0017 18.4 0.6 0.012 15.6 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand RNA_pol_Rpb4 PF03874.16 EGR34608.1 - 0.0032 17.8 0.4 1.8 8.9 0.2 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb4 YqeY PF09424.10 EGR34608.1 - 0.015 15.4 0.3 0.18 11.9 0.1 2.0 1 1 1 2 2 2 0 Yqey-like protein SurA_N_2 PF13623.6 EGR34608.1 - 0.016 15.1 0.3 1.1 9.1 0.0 2.2 1 1 1 2 2 2 0 SurA N-terminal domain DUF853 PF05872.12 EGR34608.1 - 0.017 13.8 0.2 0.41 9.2 0.1 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) EF-hand_14 PF17959.1 EGR34608.1 - 0.033 14.5 0.1 9 6.7 0.0 2.3 1 1 1 2 2 2 0 EF-hand domain SurA_N_3 PF13624.6 EGR34608.1 - 0.046 13.5 0.2 0.21 11.3 0.0 1.9 1 1 1 2 2 2 0 SurA N-terminal domain DUF4497 PF14924.6 EGR34608.1 - 0.055 13.9 0.0 6.9 7.2 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4497) Fe_hyd_lg_C PF02906.14 EGR34608.1 - 0.056 13.1 0.6 0.2 11.3 0.6 1.8 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain DUF5580 PF17743.1 EGR34608.1 - 0.061 11.9 0.0 0.061 11.9 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5580) Poly_export PF02563.16 EGR34608.1 - 0.065 13.5 0.1 8.8 6.6 0.0 3.1 1 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein TetR_C_7 PF14246.6 EGR34608.1 - 0.08 13.0 0.0 7.5 6.6 0.0 2.4 2 1 0 2 2 2 0 AefR-like transcriptional repressor, C-terminal domain SUB1_ProdP9 PF18213.1 EGR34608.1 - 0.081 12.8 2.8 2.4 8.1 0.1 2.9 1 1 2 3 3 3 0 SUB1 protease Prodomain ProdP9 MotA_activ PF09114.10 EGR34608.1 - 0.098 12.8 0.1 1.9 8.7 0.0 2.2 2 0 0 2 2 2 0 Transcription factor MotA, activation domain SapB_1 PF05184.15 EGR34608.1 - 0.13 12.3 2.6 27 4.9 0.1 3.5 4 0 0 4 4 4 0 Saposin-like type B, region 1 DUF4483 PF14825.6 EGR34609.1 - 3.3e-46 156.9 0.2 4.5e-46 156.5 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4483) SIMPL PF04402.14 EGR34610.1 - 2.1e-23 83.8 6.7 2.3e-23 83.7 6.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) SpoIISB_antitox PF14185.6 EGR34610.1 - 0.0095 15.8 2.0 1.7 8.6 0.8 3.2 2 1 0 2 2 2 2 Antitoxin SpoIISB, type II toxin-antitoxin system FIVAR PF07554.13 EGR34610.1 - 5.1 7.9 12.3 0.3 11.9 0.6 3.3 2 1 1 3 3 3 0 FIVAR domain EF-hand_7 PF13499.6 EGR34611.1 - 2.3e-08 34.4 0.4 3e-08 34.0 0.4 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGR34611.1 - 7.3e-07 28.4 1.8 9.1e-07 28.1 0.3 1.9 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EGR34611.1 - 1e-06 28.5 0.3 1.5e-06 27.9 0.3 1.3 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGR34611.1 - 2.4e-06 26.7 1.1 4.7e-06 25.8 0.4 1.9 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EGR34611.1 - 6.6e-05 22.5 0.1 0.00021 21.0 0.1 1.9 2 0 0 2 2 2 1 EF-hand domain Fer4_24 PF18109.1 EGR34611.1 - 0.0055 17.0 1.1 0.054 13.8 0.3 2.2 2 0 0 2 2 2 1 Ferredoxin I 4Fe-4S cluster domain JmjC PF02373.22 EGR34612.1 - 3e-34 117.9 4.0 7.6e-34 116.6 0.2 2.6 3 0 0 3 3 3 1 JmjC domain, hydroxylase JmjN PF02375.17 EGR34612.1 - 1.8e-13 50.2 1.2 4.6e-13 48.9 1.2 1.8 1 0 0 1 1 1 1 jmjN domain Sel1 PF08238.12 EGR34614.1 - 3.2e-42 142.0 19.9 1.4e-06 28.8 0.2 10.3 11 0 0 11 11 11 7 Sel1 repeat TPR_7 PF13176.6 EGR34614.1 - 4.8e-09 35.6 12.3 0.67 10.1 0.0 7.7 7 1 1 8 8 8 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGR34614.1 - 1.4e-06 28.0 30.2 0.11 12.7 0.0 10.4 12 0 0 12 12 10 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGR34614.1 - 5.1e-06 26.5 6.3 0.37 11.3 0.0 6.4 6 2 1 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGR34614.1 - 7.8e-06 26.2 24.0 3.1 8.6 0.1 9.5 10 1 0 10 10 10 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGR34614.1 - 9.4e-06 25.2 44.5 0.0019 17.9 0.0 11.2 12 1 0 12 12 12 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGR34614.1 - 0.00064 20.3 3.3 4 8.2 0.0 5.5 6 1 2 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGR34614.1 - 0.00076 20.1 0.2 6.8 7.8 0.0 6.2 4 2 3 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGR34614.1 - 0.023 15.0 8.9 2.2 8.6 0.5 5.9 4 2 2 6 6 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGR34614.1 - 0.069 13.7 18.3 2 9.0 0.0 6.9 6 3 1 8 8 8 0 Tetratricopeptide repeat DUF3223 PF11523.8 EGR34614.1 - 0.089 13.7 0.1 0.52 11.2 0.0 2.4 2 0 0 2 2 1 0 Protein of unknown function (DUF3223) TPR_8 PF13181.6 EGR34614.1 - 0.22 11.8 41.1 0.58 10.5 0.0 10.4 13 1 0 13 13 13 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGR34614.1 - 1.5 8.8 7.7 2.1 8.3 0.0 4.8 7 0 0 7 7 7 0 Tetratricopeptide repeat SHIPPO-rpt PF07004.12 EGR34615.1 - 3e-11 43.7 18.7 0.093 13.7 0.0 7.6 7 0 0 7 7 7 3 Sperm-tail PG-rich repeat DUF3990 PF13151.6 EGR34615.1 - 0.003 17.3 0.3 0.0061 16.2 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3990) Lipocalin_4 PF13648.6 EGR34615.1 - 6.7 7.8 17.2 12 6.9 6.5 3.1 1 1 2 3 3 3 0 Lipocalin-like domain Ras PF00071.22 EGR34616.1 - 5.6e-62 208.1 0.4 7.2e-62 207.8 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR34616.1 - 5.1e-34 117.1 0.7 1.2e-33 115.9 0.1 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR34616.1 - 2.2e-17 63.0 0.2 2.7e-17 62.7 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGR34616.1 - 4.6e-07 29.9 0.2 1.2e-06 28.6 0.1 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGR34616.1 - 1.6e-06 27.6 0.2 1.6e-06 27.6 0.2 1.4 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EGR34616.1 - 1.7e-05 24.4 0.1 0.00061 19.3 0.1 2.3 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGR34616.1 - 0.00018 21.5 2.1 0.12 12.3 0.2 2.2 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGR34616.1 - 0.0024 17.5 0.2 0.0061 16.1 0.2 1.6 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EGR34616.1 - 0.0099 16.3 0.1 0.023 15.1 0.0 1.8 2 1 0 2 2 2 1 AAA ATPase domain CPT PF07931.12 EGR34616.1 - 0.14 12.0 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein Glyco_transf_36 PF06165.11 EGR34617.1 - 0.16 11.3 0.3 0.23 10.8 0.3 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 36 Kinesin PF00225.23 EGR34618.1 - 2.4e-106 355.5 7.2 2.8e-106 355.2 7.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR34618.1 - 2.6e-32 111.8 0.7 4.8e-32 110.9 0.7 1.4 1 0 0 1 1 1 1 Microtubule binding DUF1507 PF07408.11 EGR34618.1 - 0.02 14.8 0.2 12 5.8 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1507) Cpn60_TCP1 PF00118.24 EGR34619.1 - 1.1e-152 509.1 13.4 1.2e-152 509.0 13.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Trans_coact PF16805.5 EGR34619.1 - 0.026 14.6 0.1 0.14 12.3 0.1 2.2 1 0 0 1 1 1 0 Phage late-transcription coactivator Cecropin PF00272.19 EGR34619.1 - 0.23 11.2 0.5 0.85 9.4 0.5 1.9 2 0 0 2 2 2 0 Cecropin family PrmA PF06325.13 EGR34623.1 - 7.4e-12 45.3 0.1 1.6e-11 44.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EGR34623.1 - 3.1e-11 43.8 0.0 2e-10 41.2 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGR34623.1 - 1.4e-10 41.2 0.8 2.6e-10 40.3 0.1 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGR34623.1 - 1e-08 35.7 0.0 3.9e-08 33.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EGR34623.1 - 2.5e-06 26.7 0.7 3.5e-06 26.2 0.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) MTS PF05175.14 EGR34623.1 - 2.8e-06 27.0 0.1 7.4e-06 25.6 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 EGR34623.1 - 5e-06 26.0 0.1 7.5e-06 25.4 0.1 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EGR34623.1 - 5.1e-06 26.4 0.0 1.6e-05 24.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 EGR34623.1 - 5.9e-06 26.2 1.5 9.6e-06 25.6 0.2 2.0 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase TehB PF03848.14 EGR34623.1 - 2.7e-05 23.7 2.9 0.00011 21.6 2.9 2.0 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 EGR34623.1 - 8.4e-05 22.5 2.8 0.0001 22.3 0.2 2.2 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 EGR34623.1 - 0.00023 20.3 0.1 0.00042 19.5 0.1 1.5 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 EGR34623.1 - 0.0013 19.5 1.8 0.0023 18.6 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGR34623.1 - 0.0014 18.6 1.0 0.002 18.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain DOT1 PF08123.13 EGR34623.1 - 0.0029 17.1 0.0 0.0063 16.1 0.0 1.5 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_24 PF13578.6 EGR34623.1 - 0.0032 18.5 0.0 0.0058 17.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGR34623.1 - 0.0034 17.2 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Cons_hypoth95 PF03602.15 EGR34623.1 - 0.0035 17.0 0.0 0.0085 15.7 0.0 1.6 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_16 PF10294.9 EGR34623.1 - 0.0044 16.8 0.6 0.0091 15.7 0.1 1.8 2 0 0 2 2 2 1 Lysine methyltransferase GidB PF02527.15 EGR34623.1 - 0.0094 15.3 0.1 0.024 14.0 0.1 1.7 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G FtsJ PF01728.19 EGR34623.1 - 0.013 15.7 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_2 PF00891.18 EGR34623.1 - 0.034 13.5 0.0 0.056 12.7 0.0 1.4 1 0 0 1 1 1 0 O-methyltransferase domain NADPH_Ox PF08414.10 EGR34625.1 - 0.0059 16.9 0.6 0.014 15.7 0.6 1.7 1 0 0 1 1 1 1 Respiratory burst NADPH oxidase Casc1_N PF15927.5 EGR34625.1 - 0.011 15.5 0.3 0.021 14.5 0.3 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus LptF_LptG PF03739.14 EGR34626.1 - 2 7.2 14.5 0.16 10.8 6.2 2.2 1 1 1 2 2 2 0 Lipopolysaccharide export system permease LptF/LptG Pilin_GH PF16734.5 EGR34627.1 - 0.0023 18.2 0.4 0.0023 18.2 0.4 2.4 2 0 0 2 2 2 1 Type IV pilin-like G and H, putative Chlam_PMP PF02415.17 EGR34627.1 - 0.29 11.7 0.1 0.29 11.7 0.1 8.2 9 0 0 9 9 9 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Flavoprotein PF02441.19 EGR34628.1 - 6.5e-43 146.2 0.4 2.1e-42 144.5 0.4 1.7 1 1 0 1 1 1 1 Flavoprotein Sod_Fe_C PF02777.18 EGR34628.1 - 0.055 13.6 1.6 0.11 12.7 0.3 1.9 1 1 1 2 2 2 0 Iron/manganese superoxide dismutases, C-terminal domain Sgf11_N PF18519.1 EGR34628.1 - 0.077 12.6 0.1 0.21 11.2 0.1 1.7 1 0 0 1 1 1 0 SAGA-associated factor 11 N-terminal domain RC-P840_PscD PF10657.9 EGR34631.1 - 0.01 15.9 0.2 0.015 15.4 0.2 1.5 1 1 0 1 1 1 0 Photosystem P840 reaction centre protein PscD IF4E PF01652.18 EGR34632.1 - 4.8e-28 98.0 0.1 5.3e-28 97.8 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF2475 PF10629.9 EGR34633.1 - 1.2e-06 28.6 0.5 4.6e-06 26.7 0.5 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF2475) HMG_box PF00505.19 EGR34635.1 - 5.4e-15 55.6 5.0 5.4e-15 55.6 5.0 3.1 2 1 1 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGR34635.1 - 1.4e-06 28.7 5.6 1.4e-06 28.7 5.6 3.6 1 1 2 3 3 3 1 HMG-box domain Flagellin_C PF00700.21 EGR34635.1 - 0.018 15.4 0.5 0.12 12.7 0.1 2.1 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region VitD-bind_III PF09164.10 EGR34635.1 - 0.19 11.7 0.4 0.19 11.7 0.4 2.7 2 1 0 2 2 2 0 Vitamin D binding protein, domain III ACOX PF01756.19 EGR34637.1 - 5.3e-43 146.7 1.1 1.1e-42 145.6 1.1 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EGR34637.1 - 9.3e-16 57.8 0.0 2.7e-15 56.4 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 EGR34637.1 - 1.6e-05 25.4 0.0 4.8e-05 23.9 0.0 1.9 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 EGR34637.1 - 7.2e-05 23.0 0.0 0.0007 19.8 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain FCH PF00611.23 EGR34638.1 - 0.0029 17.9 0.9 0.0076 16.5 0.9 1.8 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain ThiF PF00899.21 EGR34639.1 - 1.2e-47 162.3 0.0 5.9e-27 94.6 0.0 2.1 1 1 1 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EGR34639.1 - 0.00079 19.4 7.3 0.014 15.3 0.6 2.9 1 1 2 3 3 3 3 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 EGR34639.1 - 0.0022 18.4 0.2 0.01 16.3 0.0 2.1 2 0 0 2 2 2 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 EGR34639.1 - 0.0031 17.6 0.2 0.023 14.8 0.0 2.2 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase cNMP_binding PF00027.29 EGR34640.1 - 6.4e-48 160.8 0.0 1.3e-25 89.2 0.0 2.3 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain DUF4326 PF14216.6 EGR34640.1 - 0.044 14.5 1.7 4.7 8.0 0.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4326) cNMP_binding PF00027.29 EGR34641.1 - 1.2e-20 73.3 0.1 1.4e-11 44.3 0.0 2.8 2 2 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase PF00069.25 EGR34642.1 - 0.0021 17.4 0.0 0.0031 16.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGR34642.1 - 0.0026 16.6 0.0 0.0043 15.9 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase TPR_2 PF07719.17 EGR34644.1 - 4.2e-40 132.6 56.6 2.7e-05 24.0 0.4 17.8 20 0 0 20 20 18 10 Tetratricopeptide repeat TPR_1 PF00515.28 EGR34644.1 - 5.3e-39 130.5 72.8 3e-06 26.8 1.3 18.6 20 0 0 20 20 20 9 Tetratricopeptide repeat TPR_16 PF13432.6 EGR34644.1 - 7.2e-25 87.4 0.0 1e-05 26.1 0.0 7.4 8 1 0 8 8 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGR34644.1 - 1.8e-22 78.7 52.2 0.0033 17.1 0.0 14.3 11 5 6 17 17 16 8 TPR repeat TPR_8 PF13181.6 EGR34644.1 - 2e-20 71.2 57.7 0.0016 18.5 0.5 16.9 18 0 0 18 18 17 5 Tetratricopeptide repeat TPR_19 PF14559.6 EGR34644.1 - 9.3e-20 70.9 28.4 0.00028 21.3 1.1 10.9 7 3 4 11 11 11 6 Tetratricopeptide repeat TPR_9 PF13371.6 EGR34644.1 - 3.1e-16 59.3 0.0 0.31 11.2 0.0 8.2 7 2 2 10 10 9 5 Tetratricopeptide repeat TPR_12 PF13424.6 EGR34644.1 - 4.5e-14 52.5 22.1 0.14 12.5 0.0 11.8 9 4 1 10 10 10 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR34644.1 - 4.4e-13 49.3 50.8 0.00019 21.6 2.3 10.7 7 4 5 12 12 12 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGR34644.1 - 1.2e-12 47.6 18.9 1.6 9.6 0.1 13.7 15 0 0 15 15 14 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGR34644.1 - 1.5e-09 37.8 0.0 13 7.0 0.0 9.9 9 3 4 13 13 9 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGR34644.1 - 1.4e-07 31.4 38.0 0.73 10.4 0.6 11.2 13 0 0 13 13 12 4 Tetratricopeptide repeat TPR_20 PF14561.6 EGR34644.1 - 1.2e-06 28.7 6.1 0.85 10.0 0.0 7.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGR34644.1 - 2.1e-06 27.4 12.8 1.5 9.0 0.0 10.7 12 0 0 12 12 11 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGR34644.1 - 8.7e-06 25.3 2.3 0.59 9.4 0.1 5.3 5 1 1 6 6 6 1 MalT-like TPR region Rapsyn_N PF10579.9 EGR34644.1 - 0.0038 17.3 6.8 0.4 10.8 0.1 5.5 6 2 1 7 7 6 1 Rapsyn N-terminal myristoylation and linker region TPR_21 PF09976.9 EGR34644.1 - 0.13 12.0 7.5 0.15 11.8 1.5 4.2 4 1 2 6 6 6 0 Tetratricopeptide repeat-like domain ATP13 PF12921.7 EGR34644.1 - 1.7 8.5 5.7 4 7.3 0.6 3.6 3 0 0 3 3 3 0 Mitochondrial ATPase expression MitMem_reg PF13012.6 EGR34644.1 - 1.7 9.1 4.8 2.5 8.6 1.6 2.9 2 1 0 2 2 1 0 Maintenance of mitochondrial structure and function Syntaxin-6_N PF09177.11 EGR34644.1 - 5.9 7.5 6.9 3.4 8.3 0.0 4.0 4 1 0 4 4 3 0 Syntaxin 6, N-terminal MIT PF04212.18 EGR34644.1 - 8.6 6.5 34.7 0.88 9.7 0.1 10.9 11 3 2 13 13 13 0 MIT (microtubule interacting and transport) domain SET PF00856.28 EGR34645.1 - 4.3e-08 33.7 0.2 7.6e-08 32.9 0.2 1.6 1 1 0 1 1 1 1 SET domain Pullulanase_Ins PF18494.1 EGR34645.1 - 0.051 14.0 1.4 0.45 11.0 0.0 3.2 4 0 0 4 4 4 0 Pullulanase Ins domain Rubis-subs-bind PF09273.11 EGR34646.1 - 2.3e-17 63.9 0.3 3.1e-17 63.5 0.3 1.2 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding MMADHC PF10229.9 EGR34646.1 - 0.14 11.9 1.5 0.19 11.4 1.5 1.2 1 0 0 1 1 1 0 Methylmalonic aciduria and homocystinuria type D protein Ribosomal_S8e PF01201.22 EGR34647.1 - 6.3e-26 91.2 0.1 7.6e-26 90.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e PNTB PF02233.16 EGR34648.1 - 1e-172 575.2 22.8 2e-172 574.2 16.9 2.2 2 0 0 2 2 2 2 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EGR34648.1 - 5.4e-76 254.6 0.2 1.5e-75 253.2 0.2 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EGR34648.1 - 4.6e-42 143.5 0.1 1.3e-41 142.1 0.1 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EGR34648.1 - 5.8e-30 103.6 5.4 5.8e-30 103.6 5.4 4.1 3 1 2 5 5 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 EGR34648.1 - 3.1e-05 23.4 4.2 0.65 9.3 0.0 4.0 3 1 1 4 4 4 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EGR34648.1 - 0.0029 16.9 0.1 0.0064 15.8 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGR34648.1 - 0.074 13.3 1.4 0.4 11.0 1.4 2.3 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Citrate_bind PF16114.5 EGR34648.1 - 0.1 12.1 0.1 0.25 10.8 0.1 1.6 1 0 0 1 1 1 0 ATP citrate lyase citrate-binding IRK PF01007.20 EGR34649.1 - 0.084 12.7 0.3 0.11 12.3 0.3 1.2 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain Ribosomal_S4e PF00900.20 EGR34650.1 - 9e-30 102.4 1.3 2.6e-29 100.9 1.2 1.8 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 EGR34650.1 - 2.6e-21 75.0 0.4 1.7e-20 72.4 0.0 2.4 2 1 0 2 2 2 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EGR34650.1 - 6.5e-19 67.8 4.5 1.4e-18 66.7 4.5 1.6 1 0 0 1 1 1 1 RS4NT (NUC023) domain Sipho_tail PF05709.11 EGR34650.1 - 0.0062 16.0 0.2 0.05 13.0 0.1 2.0 2 0 0 2 2 2 1 Phage tail protein Gag_MA PF01140.19 EGR34650.1 - 0.055 13.2 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 Matrix protein (MA), p15 KOW PF00467.29 EGR34650.1 - 0.1 12.6 0.2 0.29 11.1 0.2 1.8 1 0 0 1 1 1 0 KOW motif Pkinase PF00069.25 EGR34651.1 - 1.1e-58 198.7 0.3 1.1e-58 198.7 0.3 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34651.1 - 1.1e-30 106.8 0.4 2e-30 106.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_2 PF12796.7 EGR34651.1 - 4.2e-12 46.5 0.9 9.4e-12 45.4 0.9 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGR34651.1 - 7.7e-09 35.1 2.0 0.045 14.3 0.2 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EGR34651.1 - 7.2e-08 32.6 0.6 0.0065 16.8 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 EGR34651.1 - 4.2e-06 27.0 3.9 0.013 15.9 0.2 3.1 3 0 0 3 3 3 2 Ankyrin repeat Kinase-like PF14531.6 EGR34651.1 - 2e-05 24.1 1.9 3.4e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Ank_4 PF13637.6 EGR34651.1 - 2.3e-05 24.8 1.6 0.0023 18.4 0.3 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) APH PF01636.23 EGR34651.1 - 0.008 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family TPR_12 PF13424.6 EGR34652.1 - 1.5e-08 34.8 4.4 6.7e-07 29.5 0.2 2.6 1 1 0 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGR34652.1 - 2e-06 27.5 9.4 0.063 13.2 0.2 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGR34652.1 - 4.7e-05 23.0 11.4 0.039 13.8 0.0 4.5 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGR34652.1 - 6.4e-05 22.9 9.5 0.14 12.4 0.0 5.0 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGR34652.1 - 0.00018 21.3 3.0 3.3 7.9 0.0 4.4 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGR34652.1 - 0.00031 20.6 6.8 2.9 8.2 0.0 4.9 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGR34652.1 - 0.0051 16.2 0.4 0.0051 16.2 0.4 2.8 3 0 0 3 3 3 1 MalT-like TPR region DUF3856 PF12968.7 EGR34652.1 - 0.027 14.6 2.4 1.6 8.8 0.2 3.2 1 1 3 4 4 4 0 Domain of Unknown Function (DUF3856) L27 PF02828.16 EGR34652.1 - 0.88 9.4 2.8 1.4 8.7 1.4 2.1 1 1 1 2 2 2 0 L27 domain EphA2_TM PF14575.6 EGR34652.1 - 1.4 9.9 8.4 2.6 9.0 1.4 3.5 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain VSP PF03302.13 EGR34653.1 - 0.00046 19.2 24.7 0.00046 19.2 24.7 2.1 1 1 1 2 2 2 1 Giardia variant-specific surface protein Furin-like_2 PF15913.5 EGR34653.1 - 0.013 15.6 20.0 0.013 15.6 20.0 3.4 1 1 2 3 3 3 0 Furin-like repeat, cysteine-rich AAA_6 PF12774.7 EGR34655.1 - 2e-128 428.0 22.7 2.2e-126 421.2 0.1 4.9 4 0 0 4 4 4 3 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 EGR34655.1 - 6.3e-95 318.6 19.5 6.3e-95 318.6 19.5 9.9 10 2 0 11 11 7 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EGR34655.1 - 4.1e-68 228.8 16.3 4.1e-68 228.8 16.3 6.0 7 0 0 7 7 3 1 ATP-binding dynein motor region AAA_8 PF12780.7 EGR34655.1 - 3.6e-41 141.2 4.1 3.6e-41 141.2 4.1 6.1 7 1 1 8 8 7 1 P-loop containing dynein motor region D4 AAA_lid_11 PF18198.1 EGR34655.1 - 2.7e-37 128.1 0.8 2.1e-36 125.2 0.1 2.9 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EGR34655.1 - 2.2e-36 124.9 0.0 5.3e-23 81.5 0.0 5.9 5 1 0 5 5 4 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 EGR34655.1 - 6.5e-32 110.1 3.2 1.5e-31 109.0 0.0 3.6 2 0 0 2 2 1 1 Dynein heavy chain region D6 P-loop domain AAA_7 PF12775.7 EGR34655.1 - 4.1e-29 101.4 2.3 1.9e-23 82.9 0.1 4.8 4 0 0 4 4 4 2 P-loop containing dynein motor region Dynein_C PF18199.1 EGR34655.1 - 2.1e-28 99.5 0.7 2.1e-28 99.5 0.7 3.4 3 0 0 3 3 2 1 Dynein heavy chain C-terminal domain MT PF12777.7 EGR34655.1 - 1.8e-24 86.4 16.4 5.3e-24 84.9 16.4 1.8 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_16 PF13191.6 EGR34655.1 - 8.1e-11 42.6 13.3 0.0004 20.8 0.0 8.6 8 2 1 9 9 8 3 AAA ATPase domain AAA PF00004.29 EGR34655.1 - 1.4e-10 41.7 13.4 0.12 12.8 0.0 7.8 8 0 0 8 8 7 3 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGR34655.1 - 2.5e-09 37.5 14.1 0.00093 19.5 0.0 6.7 6 1 1 7 7 5 2 AAA domain RNA_helicase PF00910.22 EGR34655.1 - 4.2e-07 30.3 2.3 0.13 12.7 0.1 5.3 5 0 0 5 5 3 2 RNA helicase AAA_28 PF13521.6 EGR34655.1 - 5e-07 30.1 0.0 0.022 15.0 0.0 4.6 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 EGR34655.1 - 9.6e-07 28.7 0.0 0.0057 16.4 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_24 PF13479.6 EGR34655.1 - 1.9e-05 24.5 9.0 0.035 13.8 0.0 5.4 4 1 1 5 5 5 2 AAA domain IstB_IS21 PF01695.17 EGR34655.1 - 3.8e-05 23.5 0.2 0.79 9.4 0.0 4.4 4 0 0 4 4 4 1 IstB-like ATP binding protein AAA_18 PF13238.6 EGR34655.1 - 0.00023 21.7 2.1 0.19 12.3 0.0 5.4 5 0 0 5 5 3 1 AAA domain AAA_19 PF13245.6 EGR34655.1 - 0.00036 20.9 0.6 3.4 8.0 0.0 4.5 4 0 0 4 4 4 1 AAA domain Mg_chelatase PF01078.21 EGR34655.1 - 0.00054 19.4 0.0 0.42 10.0 0.0 2.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI ATR13 PF16829.5 EGR34655.1 - 0.0011 19.3 0.4 0.021 15.1 0.1 3.2 3 0 0 3 3 2 1 Avirulence protein ATR13, RxLR effector AAA_33 PF13671.6 EGR34655.1 - 0.0013 18.9 0.0 2.3 8.4 0.0 3.7 3 0 0 3 3 3 1 AAA domain RsgA_GTPase PF03193.16 EGR34655.1 - 0.0022 17.9 10.2 0.22 11.4 0.0 5.5 5 0 0 5 5 4 1 RsgA GTPase ABC_tran PF00005.27 EGR34655.1 - 0.0025 18.3 0.0 0.0025 18.3 0.0 7.9 8 1 0 8 8 5 2 ABC transporter ATP-synt_ab PF00006.25 EGR34655.1 - 0.017 14.8 0.0 5.2 6.6 0.0 2.8 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain TsaE PF02367.17 EGR34655.1 - 0.043 13.8 0.2 4.7 7.2 0.0 3.9 4 0 0 4 4 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 EGR34655.1 - 0.06 13.1 0.1 8.3 6.2 0.0 3.3 3 0 0 3 3 3 0 P-loop containing region of AAA domain T2SSE PF00437.20 EGR34655.1 - 0.061 12.4 1.7 1.5 7.8 0.1 3.1 3 0 0 3 3 3 0 Type II/IV secretion system protein ERG2_Sigma1R PF04622.12 EGR34655.1 - 0.076 12.3 0.6 0.34 10.2 0.6 2.2 1 0 0 1 1 1 0 ERG2 and Sigma1 receptor like protein Spo7_2_N PF15407.6 EGR34655.1 - 0.09 12.4 0.0 0.5 10.0 0.0 2.4 1 0 0 1 1 1 0 Sporulation protein family 7 Roc PF08477.13 EGR34655.1 - 0.095 12.9 1.4 13 6.0 0.0 4.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_lid_1 PF17857.1 EGR34655.1 - 0.1 12.8 0.8 2.6 8.3 1.1 3.2 2 0 0 2 2 2 0 AAA+ lid domain NACHT PF05729.12 EGR34655.1 - 0.18 11.7 4.7 10 6.0 0.1 3.9 4 0 0 4 4 2 0 NACHT domain AAA_25 PF13481.6 EGR34655.1 - 0.2 11.2 0.0 9.6 5.7 0.0 2.7 2 0 0 2 2 2 0 AAA domain PRK PF00485.18 EGR34655.1 - 0.27 11.0 2.0 3.4 7.3 0.0 3.7 5 0 0 5 5 3 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.17 EGR34655.1 - 0.49 10.1 6.1 8 6.2 0.0 4.5 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein Pkinase PF00069.25 EGR34656.1 - 1.6e-24 86.7 0.0 1.6e-24 86.7 0.0 2.8 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34656.1 - 3.6e-10 39.6 0.0 7.5e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGR34656.1 - 0.00054 20.0 0.0 0.00081 19.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF5600 PF18150.1 EGR34656.1 - 0.29 11.7 7.0 0.74 10.4 0.1 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF5600) JmjC PF02373.22 EGR34657.1 - 1.2e-15 58.0 0.3 5.1e-15 55.9 0.0 2.1 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-C5HC2 PF02928.16 EGR34657.1 - 0.00035 20.9 13.3 0.00073 19.9 13.3 1.5 1 0 0 1 1 1 1 C5HC2 zinc finger GBP PF02263.19 EGR34658.1 - 6.9e-64 215.6 5.6 1.1e-63 214.9 5.6 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 EGR34658.1 - 4.7e-09 36.1 0.7 4.7e-09 36.1 0.7 2.3 1 1 1 2 2 2 1 Guanylate-binding protein, C-terminal domain MMR_HSR1 PF01926.23 EGR34658.1 - 0.021 14.9 0.5 0.12 12.5 0.5 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_14 PF13173.6 EGR34658.1 - 0.37 10.8 0.1 0.37 10.8 0.1 3.7 4 1 0 4 4 4 0 AAA domain PET PF06297.14 EGR34658.1 - 4.9 7.5 8.0 0.52 10.7 1.3 2.8 2 1 1 3 3 3 0 PET Domain RCC1 PF00415.18 EGR34659.1 - 1.5e-14 54.3 3.6 2.8e-12 47.0 0.0 2.9 3 0 0 3 3 3 2 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR34659.1 - 2.4e-07 30.4 6.6 0.0031 17.3 0.2 2.3 2 0 0 2 2 2 2 Regulator of chromosome condensation (RCC1) repeat MFS_1 PF07690.16 EGR34660.1 - 8.5e-36 123.6 35.3 2.5e-33 115.5 13.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGR34660.1 - 1.8e-22 79.9 31.4 4.4e-22 78.6 31.3 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 EGR34660.1 - 6e-05 22.5 0.9 6e-05 22.5 0.9 1.9 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB TPR_19 PF14559.6 EGR34660.1 - 0.098 13.2 0.0 0.18 12.4 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-C4pol PF14260.6 EGR34661.1 - 0.33 11.4 10.1 23 5.6 11.2 2.4 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta Ephrin_rec_like PF07699.13 EGR34662.1 - 0.0071 16.1 3.7 0.0071 16.1 3.7 2.5 2 0 0 2 2 2 1 Putative ephrin-receptor like EF-hand_7 PF13499.6 EGR34664.1 - 0.0056 17.1 1.3 0.01 16.2 0.1 2.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGR34664.1 - 0.017 15.0 1.8 0.028 14.4 0.5 2.1 2 0 0 2 2 2 0 EF-hand domain EF-hand_8 PF13833.6 EGR34664.1 - 0.017 14.9 1.2 0.099 12.5 0.5 2.2 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_1 PF00036.32 EGR34664.1 - 0.11 12.1 0.7 0.11 12.1 0.7 2.3 3 0 0 3 3 3 0 EF hand Mito_carr PF00153.27 EGR34665.1 - 3.4e-60 200.0 6.3 7.6e-21 73.8 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Peptidase_S29 PF02907.15 EGR34665.1 - 0.016 14.9 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Acyl_transf_3 PF01757.22 EGR34665.1 - 0.038 13.0 1.4 0.068 12.2 1.4 1.5 1 0 0 1 1 1 0 Acyltransferase family Pkinase PF00069.25 EGR34666.1 - 5e-56 190.0 0.7 6.2e-56 189.7 0.7 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34666.1 - 2.1e-30 105.9 0.0 2.8e-30 105.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR34666.1 - 0.0064 15.8 0.0 0.018 14.4 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGR34666.1 - 0.11 11.3 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase EF-hand_7 PF13499.6 EGR34667.1 - 1.8e-08 34.7 0.1 0.0002 21.8 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR34667.1 - 1e-07 31.3 0.0 0.017 15.0 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGR34667.1 - 0.0012 18.2 0.1 0.046 13.3 0.0 2.6 2 0 0 2 2 2 1 EF hand EF-hand_9 PF14658.6 EGR34667.1 - 0.0037 17.6 0.0 0.2 12.0 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain DUF2666 PF10869.8 EGR34667.1 - 0.033 14.4 1.2 0.085 13.1 0.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) Helicase_C PF00271.31 EGR34669.1 - 1e-10 42.0 1.8 2e-10 41.0 0.1 2.3 2 1 1 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGR34669.1 - 2.2e-10 40.6 1.0 2.2e-10 40.6 1.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGR34669.1 - 0.0002 21.7 0.1 0.00053 20.3 0.1 1.7 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EGR34669.1 - 0.00046 19.7 0.2 0.0015 18.0 0.1 1.9 2 0 0 2 2 2 1 PhoH-like protein Flavi_DEAD PF07652.14 EGR34669.1 - 0.00065 19.7 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Flavivirus DEAD domain AAA_30 PF13604.6 EGR34669.1 - 0.00086 19.1 0.0 0.0013 18.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGR34669.1 - 0.0031 17.8 0.1 0.0081 16.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain T2SSE PF00437.20 EGR34669.1 - 0.0054 15.8 0.0 0.011 14.8 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein Helicase_RecD PF05127.14 EGR34669.1 - 0.021 14.7 0.1 0.058 13.3 0.1 1.9 1 1 0 1 1 1 0 Helicase RsgA_GTPase PF03193.16 EGR34669.1 - 0.031 14.2 0.7 0.1 12.5 0.0 2.2 3 0 0 3 3 3 0 RsgA GTPase ATPase_2 PF01637.18 EGR34669.1 - 0.063 13.2 2.0 0.11 12.4 2.0 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 EGR34669.1 - 0.067 12.9 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 EGR34669.1 - 0.076 12.7 0.1 0.14 11.9 0.1 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 EGR34669.1 - 0.13 12.7 0.0 0.13 12.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 EGR34669.1 - 0.18 11.9 4.0 4 7.5 4.0 2.9 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGR34669.1 - 0.83 10.2 8.4 0.086 13.3 3.4 2.1 2 1 0 2 2 2 0 ABC transporter Kinesin PF00225.23 EGR34671.1 - 3.6e-118 394.3 1.7 4.6e-118 394.0 1.7 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGR34671.1 - 4.3e-26 91.6 0.4 8.5e-26 90.7 0.4 1.4 1 0 0 1 1 1 1 Microtubule binding CLU PF13236.6 EGR34672.1 - 4.3e-72 242.5 0.0 4.3e-72 242.5 0.0 2.0 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.7 EGR34672.1 - 1.9e-31 109.4 1.6 1.9e-31 109.4 1.6 4.3 5 0 0 5 5 4 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 EGR34672.1 - 1.9e-28 98.5 11.0 1.1e-09 38.5 0.2 3.8 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 EGR34672.1 - 5.1e-12 45.3 0.1 0.021 14.7 0.0 6.0 6 0 0 6 6 6 4 Tetratricopeptide repeat CLU_N PF15044.6 EGR34672.1 - 2.1e-09 37.6 2.1 2.1e-09 37.6 2.1 3.3 2 1 1 3 3 3 1 Mitochondrial function, CLU-N-term TPR_2 PF07719.17 EGR34672.1 - 3e-07 30.0 22.0 0.016 15.3 0.2 6.6 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGR34672.1 - 0.00014 21.8 26.1 0.04 14.1 0.2 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGR34672.1 - 0.0007 19.3 26.9 0.036 13.9 0.6 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_MalT PF17874.1 EGR34672.1 - 0.001 18.5 1.1 0.048 13.0 0.1 2.7 2 1 0 3 3 3 1 MalT-like TPR region MIT PF04212.18 EGR34672.1 - 0.058 13.5 0.1 0.058 13.5 0.1 3.9 5 0 0 5 5 4 0 MIT (microtubule interacting and transport) domain TPR_7 PF13176.6 EGR34672.1 - 0.06 13.4 5.4 27 5.1 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat EF-hand_1 PF00036.32 EGR34673.1 - 1.3e-09 36.9 1.1 4.3e-06 25.9 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EGR34673.1 - 3.1e-08 32.9 1.2 0.00016 21.3 0.0 2.9 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 EGR34673.1 - 1e-06 29.1 0.3 0.00057 20.3 0.1 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGR34673.1 - 3.4e-06 26.3 7.9 5.3e-05 22.5 0.0 3.3 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 EGR34673.1 - 0.00043 20.1 0.4 0.0046 16.8 0.4 2.3 1 1 0 1 1 1 1 EF-hand domain pair CENP-B_dimeris PF09026.10 EGR34674.1 - 0.012 16.0 10.2 0.013 15.9 10.2 1.1 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3464 PF11947.8 EGR34674.1 - 0.05 13.4 2.4 0.053 13.3 2.4 1.1 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 SseC PF04888.12 EGR34674.1 - 0.067 12.8 0.6 0.07 12.7 0.6 1.0 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Tom22 PF04281.13 EGR34674.1 - 0.12 12.1 4.0 0.13 12.1 4.0 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 NPR3 PF03666.13 EGR34674.1 - 0.16 10.7 2.1 0.15 10.9 2.1 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM176 PF14851.6 EGR34674.1 - 0.23 11.1 7.6 0.24 11.0 7.6 1.1 1 0 0 1 1 1 0 FAM176 family GOLD_2 PF13897.6 EGR34674.1 - 0.33 11.4 2.9 0.33 11.4 2.9 1.1 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking PPL5 PF18168.1 EGR34674.1 - 0.48 9.7 3.2 0.48 9.7 3.2 1.0 1 0 0 1 1 1 0 Prim-pol family 5 RXT2_N PF08595.11 EGR34674.1 - 0.49 10.4 10.7 0.53 10.3 10.7 1.1 1 0 0 1 1 1 0 RXT2-like, N-terminal WRNPLPNID PF15017.6 EGR34674.1 - 0.58 11.1 11.5 0.75 10.7 11.5 1.3 1 0 0 1 1 1 0 Putative WW-binding domain and destruction box Cwf_Cwc_15 PF04889.12 EGR34674.1 - 0.69 9.6 13.3 0.73 9.5 13.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Cytomega_UL84 PF06284.11 EGR34674.1 - 0.91 7.9 5.6 1 7.7 5.6 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein PBP1_TM PF14812.6 EGR34674.1 - 1.2 9.5 11.4 1.5 9.2 11.4 1.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RRN3 PF05327.11 EGR34674.1 - 3.6 6.0 9.2 3.3 6.1 9.2 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 EGR34674.1 - 6.9 4.6 16.9 7.5 4.5 16.9 1.0 1 0 0 1 1 1 0 DNA polymerase phi FYDLN_acid PF09538.10 EGR34674.1 - 7.1 7.4 15.3 8.2 7.2 15.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Acid_phosphat_B PF03767.14 EGR34675.1 - 0.018 14.6 3.9 0.02 14.5 3.9 1.0 1 0 0 1 1 1 0 HAD superfamily, subfamily IIIB (Acid phosphatase) Band_7 PF01145.25 EGR34676.1 - 4.2e-29 101.8 2.3 5.6e-29 101.4 2.3 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Ras PF00071.22 EGR34677.1 - 2.5e-60 202.8 2.1 2.9e-60 202.5 2.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR34677.1 - 1.4e-30 105.9 0.7 2.4e-30 105.2 0.7 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR34677.1 - 3.5e-15 55.9 0.8 4.2e-15 55.6 0.8 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGR34677.1 - 6.6e-06 26.1 0.2 0.0038 17.1 0.1 2.2 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EGR34677.1 - 0.00011 21.6 1.0 0.00053 19.4 1.0 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGR34677.1 - 0.00043 19.8 0.1 0.00055 19.4 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EGR34677.1 - 0.003 17.1 2.2 0.0044 16.6 0.7 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 EGR34677.1 - 0.0051 16.6 1.0 0.016 15.0 0.1 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 EGR34677.1 - 0.0078 15.8 0.5 0.068 12.7 0.5 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B CbiA PF01656.23 EGR34677.1 - 0.054 13.6 0.4 0.22 11.6 0.4 2.2 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.6 EGR34677.1 - 0.056 13.2 2.3 0.19 11.4 2.3 1.9 1 1 0 1 1 1 0 AAA domain TOPRIM_C PF16898.5 EGR34677.1 - 0.094 13.0 1.0 0.26 11.5 0.3 1.8 1 1 1 2 2 2 0 C-terminal associated domain of TOPRIM Sen15 PF09631.10 EGR34677.1 - 0.11 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Sen15 protein AAA_5 PF07728.14 EGR34677.1 - 0.11 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Thiolase_N PF00108.23 EGR34678.1 - 2.6e-88 295.8 0.3 3.3e-88 295.4 0.3 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGR34678.1 - 2e-42 143.7 0.6 4.4e-42 142.6 0.6 1.6 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGR34678.1 - 0.0001 22.0 0.7 0.0017 18.0 0.5 2.2 1 1 1 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGR34678.1 - 0.13 12.1 4.2 0.17 11.7 0.2 3.1 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Pkinase PF00069.25 EGR34680.1 - 3.8e-16 59.2 0.0 6.5e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34680.1 - 7e-06 25.5 0.0 1.2e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase TFIIS_M PF07500.14 EGR34680.1 - 0.11 13.0 0.0 0.31 11.5 0.0 1.8 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS), central domain Pkinase PF00069.25 EGR34681.1 - 5.2e-06 26.0 0.4 5.8e-06 25.9 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Ion_trans PF00520.31 EGR34682.1 - 0.017 14.3 39.6 0.049 12.9 34.7 3.0 2 1 0 2 2 2 0 Ion transport protein Wzz PF02706.15 EGR34682.1 - 1.8 8.9 7.0 0.91 9.9 0.3 3.0 3 0 0 3 3 3 0 Chain length determinant protein Ins145_P3_rec PF08709.11 EGR34684.1 - 2.4e-15 56.3 3.9 1.5e-13 50.5 1.5 2.4 2 0 0 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor MIR PF02815.19 EGR34684.1 - 5e-12 46.0 10.6 8.3e-11 42.1 0.6 2.8 2 1 0 2 2 2 2 MIR domain DUF4200 PF13863.6 EGR34685.1 - 1.5e-16 60.9 24.5 1.5e-16 60.9 24.5 3.6 2 1 0 3 3 3 1 Domain of unknown function (DUF4200) PX PF00787.24 EGR34686.1 - 0.027 14.4 0.7 0.027 14.4 0.7 3.1 4 1 1 5 5 5 0 PX domain E3_UbLigase_R4 PF13764.6 EGR34687.1 - 4.5e-66 223.6 18.4 5.3e-66 223.4 18.4 1.0 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase UBR4 E3_UbLigase_R4 PF13764.6 EGR34688.1 - 1.2e-12 46.9 0.1 1.2e-12 46.9 0.1 4.5 3 1 0 4 4 4 1 E3 ubiquitin-protein ligase UBR4 Sacchrp_dh_C PF16653.5 EGR34688.1 - 0.0017 18.5 0.3 0.035 14.2 0.3 2.4 2 0 0 2 2 2 1 Saccharopine dehydrogenase C-terminal domain HECT PF00632.25 EGR34689.1 - 2.1e-97 326.3 5.4 2.1e-97 326.3 5.4 1.5 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Peptidase_S49_N PF08496.10 EGR34689.1 - 0.038 14.1 1.1 0.069 13.2 1.1 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Lip_prot_lig_C PF10437.9 EGR34691.1 - 1e-12 47.8 0.3 3.4e-12 46.2 0.3 2.0 1 0 0 1 1 1 1 Bacterial lipoate protein ligase C-terminus BPL_LplA_LipB PF03099.19 EGR34691.1 - 5.5e-08 32.8 0.0 1.9e-07 31.1 0.0 1.9 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Peptidase_M8 PF01457.16 EGR34692.1 - 8e-42 143.6 10.4 2e-36 125.8 0.2 2.1 1 1 1 2 2 2 2 Leishmanolysin EGF_Tenascin PF18720.1 EGR34692.1 - 6.3e-08 32.5 10.1 6.3e-08 32.5 10.1 2.8 2 0 0 2 2 2 1 Tenascin EGF domain EGF_2 PF07974.13 EGR34692.1 - 0.0021 18.4 16.6 0.0021 18.4 16.6 3.3 2 1 0 2 2 2 1 EGF-like domain ChlamPMP_M PF07548.11 EGR34694.1 - 0.1 12.5 1.5 0.66 9.9 1.1 2.2 2 0 0 2 2 2 0 Chlamydia polymorphic membrane protein middle domain DUF1664 PF07889.12 EGR34694.1 - 1.3 9.1 24.2 3.8 7.6 1.5 4.5 3 2 1 4 4 4 0 Protein of unknown function (DUF1664) Pox_A_type_inc PF04508.12 EGR34694.1 - 3 7.8 5.5 9.7 6.2 0.2 3.5 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat YtxH PF12732.7 EGR34694.1 - 6.2 7.4 12.9 7.7 7.1 2.5 4.2 2 1 1 3 3 3 0 YtxH-like protein FtsJ PF01728.19 EGR34695.1 - 4.1e-52 176.9 0.2 8.8e-52 175.8 0.2 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EGR34695.1 - 3.1e-28 98.6 31.4 3.1e-28 98.6 31.4 4.7 3 2 0 4 4 4 1 Domain of unknown function (DUF3381) PmrD PF11183.8 EGR34696.1 - 0.052 13.7 3.0 0.26 11.4 0.2 2.6 2 1 0 2 2 2 0 Polymyxin resistance protein PmrD La_HTH_kDCL PF18177.1 EGR34697.1 - 0.12 12.7 0.7 2.7 8.4 0.0 2.8 2 0 0 2 2 2 0 La HTH in kinetoplastid DICER domain HALZ PF02183.18 EGR34697.1 - 0.18 12.1 0.1 0.18 12.1 0.1 4.8 5 0 0 5 5 5 0 Homeobox associated leucine zipper Calycin_like PF13944.6 EGR34697.1 - 2.8 8.3 10.2 6.6 7.1 0.4 3.1 3 0 0 3 3 3 0 Calycin-like beta-barrel domain Romo1 PF10247.9 EGR34698.1 - 1.6e-08 34.8 13.0 2.4e-08 34.2 13.0 1.3 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Gly-zipper_Omp PF13488.6 EGR34698.1 - 0.0005 20.0 2.9 0.0005 20.0 2.9 1.5 2 0 0 2 2 2 1 Glycine zipper Gly-zipper_YMGG PF13441.6 EGR34698.1 - 0.0085 15.8 2.7 0.015 15.0 2.7 1.3 1 0 0 1 1 1 1 YMGG-like Gly-zipper Rick_17kDa_Anti PF05433.15 EGR34698.1 - 0.036 13.9 2.4 0.054 13.4 2.4 1.4 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.6 EGR34698.1 - 0.67 9.8 7.5 0.082 12.7 3.6 1.6 2 0 0 2 2 2 0 Glycine-zipper domain DUF1269 PF06897.12 EGR34698.1 - 1.1 9.6 5.2 0.94 9.8 3.6 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1269) Pkinase PF00069.25 EGR34699.1 - 7.9e-70 235.2 0.8 7.9e-70 235.2 0.8 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34699.1 - 9e-38 130.0 0.8 1.4e-37 129.4 0.1 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_7 PF13499.6 EGR34699.1 - 2e-16 60.2 0.1 2.4e-07 31.1 0.1 2.8 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR34699.1 - 3.4e-12 45.3 1.7 9.3e-05 22.1 0.2 4.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 EGR34699.1 - 1.6e-09 36.6 2.4 0.00034 20.0 0.2 4.1 3 0 0 3 3 3 2 EF hand Kdo PF06293.14 EGR34699.1 - 7.3e-08 32.0 0.3 2.1e-07 30.5 0.3 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGR34699.1 - 7.8e-05 21.6 0.0 0.00037 19.4 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase EF-hand_5 PF13202.6 EGR34699.1 - 8.1e-05 21.9 4.1 0.025 14.1 0.4 3.4 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EGR34699.1 - 0.00061 19.6 3.5 0.28 11.1 0.0 3.9 2 2 1 3 3 3 2 EF-hand domain pair APH PF01636.23 EGR34699.1 - 0.00067 19.6 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family EF-hand_14 PF17959.1 EGR34699.1 - 0.0034 17.7 2.4 12 6.3 0.1 4.5 3 1 1 4 4 4 1 EF-hand domain EF-hand_9 PF14658.6 EGR34699.1 - 0.0098 16.2 0.0 4.1 7.8 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain ThylakoidFormat PF11264.8 EGR34699.1 - 0.022 14.4 4.7 0.037 13.7 2.2 2.4 2 0 0 2 2 2 0 Thylakoid formation protein CBP_BcsR PF10945.8 EGR34699.1 - 0.1 12.1 0.2 0.24 10.9 0.2 1.7 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsR FTA2 PF13095.6 EGR34699.1 - 3.6 7.2 7.4 6.2 6.4 0.1 3.4 3 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 Peptidase_M24 PF00557.24 EGR34700.1 - 1.7e-38 132.4 0.0 2.3e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 RNA_polI_A14 PF08203.11 EGR34700.1 - 0.99 10.2 4.7 2.2 9.0 4.7 1.6 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Tae4 PF14113.6 EGR34700.1 - 3 8.1 6.2 95 3.2 0.0 2.8 3 0 0 3 3 3 0 Type VI secretion system (T6SS), amidase effector protein 4 ATP-synt_C PF00137.21 EGR34701.1 - 5.9e-20 71.4 25.7 4.9e-11 42.8 13.1 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Glycophorin_A PF01102.18 EGR34701.1 - 0.53 10.5 1.8 0.72 10.1 1.8 1.2 1 0 0 1 1 1 0 Glycophorin A Talin_middle PF09141.10 EGR34702.1 - 0.0012 18.9 0.5 0.002 18.2 0.5 1.4 1 0 0 1 1 1 1 Talin, middle domain Death PF00531.22 EGR34702.1 - 0.017 15.3 9.1 0.24 11.6 1.1 2.4 1 1 1 2 2 2 0 Death domain DUF508 PF04370.12 EGR34702.1 - 0.025 14.3 2.1 0.044 13.5 2.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF508) p25-alpha PF05517.12 EGR34702.1 - 0.058 13.6 4.1 0.1 12.7 4.1 1.6 1 0 0 1 1 1 0 p25-alpha CENP-O PF09496.10 EGR34702.1 - 0.6 10.1 7.5 0.87 9.5 7.3 1.3 1 1 0 1 1 1 0 Cenp-O kinetochore centromere component Ribosomal_L2_C PF03947.18 EGR34703.1 - 1.6e-47 160.9 3.5 2.3e-47 160.3 3.5 1.2 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EGR34703.1 - 1.2e-12 47.6 1.1 2.3e-12 46.7 0.4 1.9 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Myb_DNA-binding PF00249.31 EGR34704.1 - 7.2e-29 99.7 14.7 8.5e-14 51.5 1.1 4.2 4 0 0 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGR34704.1 - 3.6e-21 75.2 5.1 6.4e-14 51.9 0.8 4.9 3 2 1 4 4 4 3 Myb-like DNA-binding domain SLIDE PF09111.10 EGR34704.1 - 0.0023 18.0 3.4 0.0023 18.0 3.4 4.9 4 2 2 6 6 6 2 SLIDE Rap1_C PF11626.8 EGR34704.1 - 0.046 13.8 9.6 25 5.1 5.9 4.2 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Sporozoite_P67 PF05642.11 EGR34704.1 - 0.12 10.4 11.9 0.17 9.9 11.9 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen 2-oxoacid_dh PF00198.23 EGR34705.1 - 3.4e-74 249.2 0.0 5.7e-74 248.5 0.0 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 EGR34705.1 - 1.8e-23 82.5 0.6 2.7e-12 46.8 0.1 2.4 2 0 0 2 2 2 2 e3 binding domain Biotin_lipoyl PF00364.22 EGR34705.1 - 1.8e-14 53.3 0.3 5e-14 51.9 0.1 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 EGR34705.1 - 0.0087 15.9 0.6 0.2 11.5 0.2 2.9 2 1 1 3 3 3 1 Biotin-lipoyl like DUF1493 PF07377.12 EGR34705.1 - 0.16 12.4 5.3 0.23 11.9 0.8 3.0 2 2 1 3 3 3 0 Protein of unknown function (DUF1493) DUF1840 PF08895.11 EGR34705.1 - 2.2 8.7 7.6 4.4 7.7 2.8 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) RRM_1 PF00076.22 EGR34706.1 - 4.2e-14 52.1 0.1 8.2e-14 51.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DcuA_DcuB PF03605.14 EGR34706.1 - 0.068 12.0 1.2 0.09 11.7 1.2 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter PRP1_N PF06424.12 EGR34706.1 - 0.09 13.2 7.2 0.2 12.0 7.2 1.5 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Methyltransf_12 PF08242.12 EGR34706.1 - 3.3 8.5 7.9 6.3 7.6 6.8 2.1 1 1 0 1 1 1 0 Methyltransferase domain Castor1_N PF18700.1 EGR34707.1 - 0.031 14.1 0.5 0.059 13.2 0.5 1.5 1 0 0 1 1 1 0 Cytosolic arginine sensor for mTORC1 subunit 1 N-terminal domain Pkinase PF00069.25 EGR34708.1 - 8.5e-68 228.6 0.5 1.1e-67 228.3 0.5 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34708.1 - 7.4e-38 130.3 0.7 1.2e-37 129.6 0.1 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR34708.1 - 1.7e-05 24.3 0.3 2.7e-05 23.6 0.3 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGR34708.1 - 0.00022 20.6 0.3 0.00035 20.0 0.3 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pet127 PF08634.10 EGR34709.1 - 3.9e-84 282.3 3.1 6.9e-84 281.5 3.1 1.4 1 0 0 1 1 1 1 Mitochondrial protein Pet127 Evf PF18270.1 EGR34711.1 - 0.037 13.5 0.2 0.039 13.4 0.2 1.2 1 0 0 1 1 1 0 Virulence factor Evf DUF468 PF04318.12 EGR34711.1 - 0.083 13.6 0.1 0.13 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF468) Aminotran_1_2 PF00155.21 EGR34712.1 - 1.7e-33 116.3 0.0 2.3e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGR34712.1 - 0.00014 20.5 0.0 0.00023 19.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EGR34712.1 - 0.0013 18.1 0.0 0.0024 17.2 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase LZ3wCH PF18517.1 EGR34712.1 - 0.011 15.8 0.6 0.073 13.2 0.0 2.5 2 0 0 2 2 2 0 Leucine zipper with capping helix domain Aminotran_3 PF00202.21 EGR34712.1 - 0.011 14.4 0.1 0.034 12.8 0.1 1.6 1 1 0 1 1 1 0 Aminotransferase class-III YtxH PF12732.7 EGR34712.1 - 0.78 10.3 5.0 7.3 7.2 0.0 2.6 2 0 0 2 2 2 0 YtxH-like protein COMM_domain PF07258.14 EGR34715.1 - 0.0021 18.1 1.7 0.0056 16.8 0.1 2.5 3 0 0 3 3 3 1 COMM domain YjcQ PF09639.10 EGR34715.1 - 0.036 14.3 1.4 0.067 13.4 1.4 1.5 1 0 0 1 1 1 0 YjcQ protein Cas6b_C PF17262.2 EGR34715.1 - 0.45 10.6 5.4 1.2 9.3 0.8 2.4 1 1 1 2 2 2 0 Cas6b C-terminal domain Pkinase PF00069.25 EGR34716.1 - 5.2e-35 121.1 1.3 7.6e-35 120.5 0.1 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34716.1 - 5.6e-22 78.3 0.0 1.2e-21 77.2 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR34716.1 - 1.8e-07 30.7 0.0 6.7e-07 28.9 0.0 2.0 1 1 0 1 1 1 1 Kinase-like Pkinase PF00069.25 EGR34717.1 - 6.8e-66 222.3 0.6 8.4e-66 222.0 0.6 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34717.1 - 5e-44 150.5 0.2 5.8e-44 150.3 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR34717.1 - 9e-06 25.2 0.3 8.6e-05 22.0 0.3 2.2 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGR34717.1 - 3.5e-05 22.8 0.0 7.4e-05 21.7 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGR34717.1 - 0.092 12.1 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EGR34718.1 - 9.1e-26 90.8 4.7 2.1e-25 89.6 4.7 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34718.1 - 1e-20 74.1 0.5 2.2e-20 73.0 0.5 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ras PF00071.22 EGR34718.1 - 2.1e-10 40.5 3.6 2.1e-09 37.2 0.7 2.8 2 0 0 2 2 2 1 Ras family Arf PF00025.21 EGR34718.1 - 0.005 16.3 0.5 0.013 14.9 0.5 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGR34718.1 - 0.013 15.7 0.2 5.6 7.2 0.0 3.0 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_lid_9 PF17871.1 EGR34718.1 - 0.16 11.9 0.2 0.16 11.9 0.2 2.3 2 0 0 2 2 2 0 AAA lid domain RsgA_GTPase PF03193.16 EGR34718.1 - 0.16 11.8 2.3 0.26 11.2 0.4 2.3 2 0 0 2 2 2 0 RsgA GTPase Peptidase_S9 PF00326.21 EGR34719.1 - 8.2e-12 45.0 0.0 1.3e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGR34719.1 - 1.7e-11 43.9 0.0 3.2e-06 26.6 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGR34719.1 - 1.3e-09 38.1 0.7 0.00097 18.9 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.12 EGR34719.1 - 4.6e-08 32.1 1.2 6.4e-05 21.8 0.3 3.2 1 1 1 2 2 2 2 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 EGR34719.1 - 4.9e-06 26.6 0.1 0.019 14.9 0.0 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 EGR34719.1 - 5.1e-06 26.2 0.0 4.2e-05 23.2 0.0 2.3 1 1 1 2 2 2 1 Dienelactone hydrolase family Peptidase_S15 PF02129.18 EGR34719.1 - 9.9e-05 22.1 0.0 0.014 15.1 0.0 2.1 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 EGR34719.1 - 0.00032 20.4 0.0 0.0006 19.5 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Peptidase_S10 PF00450.22 EGR34719.1 - 0.00046 19.7 4.0 0.00067 19.2 4.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_2 PF02230.16 EGR34719.1 - 0.00092 19.1 0.3 0.14 12.0 0.0 2.2 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.7 EGR34719.1 - 0.0032 17.2 0.2 0.18 11.5 0.1 2.2 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EGR34719.1 - 0.022 14.6 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF829 PF05705.14 EGR34719.1 - 0.024 14.5 1.0 0.11 12.4 1.0 1.9 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) HSR PF03172.13 EGR34719.1 - 0.11 12.6 1.2 0.46 10.7 0.2 2.4 2 1 1 3 3 2 0 HSR domain Motilin_assoc PF04643.12 EGR34719.1 - 0.16 11.8 0.1 0.38 10.7 0.1 1.5 1 0 0 1 1 1 0 Motilin/ghrelin-associated peptide CSN8_PSD8_EIF3K PF10075.9 EGR34720.1 - 1e-16 61.2 1.3 1e-16 61.2 1.3 1.8 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EGR34720.1 - 9.5e-08 31.8 2.7 1.3e-07 31.3 2.7 1.1 1 0 0 1 1 1 1 SAC3/GANP family FTO_CTD PF12934.7 EGR34720.1 - 0.067 12.9 0.2 0.11 12.3 0.2 1.3 1 0 0 1 1 1 0 FTO C-terminal domain Gpr1_Fun34_YaaH PF01184.19 EGR34721.1 - 6.1e-44 150.1 14.8 7.1e-44 149.9 14.8 1.0 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF2512 PF10710.9 EGR34721.1 - 0.1 12.3 5.7 0.18 11.4 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2512) FAM70 PF14967.6 EGR34721.1 - 0.57 9.6 3.3 0.9 8.9 3.3 1.2 1 0 0 1 1 1 0 FAM70 protein Pkinase PF00069.25 EGR34722.1 - 3.5e-46 157.7 1.1 5.8e-22 78.3 0.0 3.2 2 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34722.1 - 1.8e-17 63.5 1.3 2.1e-10 40.4 0.1 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 EGR34722.1 - 4.6e-07 29.4 0.1 4.6e-07 29.4 0.1 3.2 3 1 1 4 4 4 1 Kinase-like Kdo PF06293.14 EGR34722.1 - 2.3e-06 27.1 0.1 4.6e-06 26.1 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGR34722.1 - 0.00075 19.5 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGR34722.1 - 0.00083 18.2 0.1 0.00083 18.2 0.1 1.6 2 0 0 2 2 2 1 Fungal protein kinase Seadorna_VP7 PF07387.11 EGR34722.1 - 0.0017 17.5 0.3 0.016 14.3 0.0 2.2 2 0 0 2 2 2 1 Seadornavirus VP7 FTA2 PF13095.6 EGR34722.1 - 0.23 11.1 0.0 0.23 11.1 0.0 2.6 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 DUF2203 PF09969.9 EGR34722.1 - 1.4 9.7 9.2 0.13 13.0 1.1 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF948 PF06103.11 EGR34722.1 - 1.6 9.0 4.5 2.5 8.4 3.4 1.9 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Exonuc_VII_L PF02601.15 EGR34722.1 - 3.1 7.3 12.7 0.11 12.1 3.3 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit Peptidase_C1 PF00112.23 EGR34723.1 - 7.6e-66 222.3 9.3 7.6e-66 222.3 9.3 1.4 2 0 0 2 2 2 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGR34723.1 - 2.6e-06 26.5 5.3 0.00033 19.6 0.1 2.9 2 1 1 3 3 3 2 Peptidase C1-like family Inhibitor_I29 PF08246.12 EGR34723.1 - 1.5e-05 25.4 7.3 2.3e-05 24.7 4.4 2.6 2 1 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) ROK PF00480.20 EGR34724.1 - 4.9e-44 151.0 0.5 5.9e-44 150.7 0.5 1.0 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.16 EGR34724.1 - 0.064 12.3 1.2 0.089 11.8 0.5 1.6 1 1 1 2 2 2 0 Glucokinase Chromate_transp PF02417.15 EGR34725.1 - 6.6e-54 182.3 29.3 6.6e-32 110.8 13.3 2.2 2 0 0 2 2 2 2 Chromate transporter Kinocilin PF15033.6 EGR34725.1 - 0.93 9.1 4.2 5 6.8 0.0 3.1 2 1 1 3 3 3 0 Kinocilin protein ETC_C1_NDUFA4 PF04800.12 EGR34726.1 - 5.2e-25 87.5 3.1 6.7e-25 87.2 2.0 1.7 2 0 0 2 2 2 1 ETC complex I subunit conserved region Phage_ABA_S PF18066.1 EGR34726.1 - 0.17 12.6 0.1 0.3 11.8 0.1 1.5 1 0 0 1 1 1 0 Phage ABA sandwich domain OTU PF02338.19 EGR34728.1 - 5e-14 52.9 0.1 5e-14 52.9 0.1 3.0 1 1 2 3 3 3 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGR34728.1 - 3.3e-06 26.7 11.7 0.0051 16.3 0.1 3.2 1 1 1 3 3 3 2 Peptidase C65 Otubain SEC-C PF02810.15 EGR34728.1 - 3.9e-06 26.7 7.3 6.5e-06 26.0 7.3 1.4 1 0 0 1 1 1 1 SEC-C motif GAF PF01590.26 EGR34729.1 - 6.5e-19 68.9 0.0 1.2e-15 58.3 0.0 2.1 2 0 0 2 2 2 2 GAF domain GAF_2 PF13185.6 EGR34729.1 - 2.6e-07 31.0 0.0 1.6e-05 25.2 0.0 2.2 2 0 0 2 2 2 1 GAF domain DUF3369 PF11849.8 EGR34729.1 - 0.0023 18.1 2.0 0.74 10.0 0.2 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF3369) DUF1251 PF06856.11 EGR34729.1 - 0.026 14.2 0.2 0.026 14.2 0.2 3.0 2 1 2 4 4 4 0 Protein of unknown function (DUF1251) GAF_3 PF13492.6 EGR34729.1 - 0.14 12.5 0.0 1.1 9.7 0.0 2.2 2 1 0 2 2 2 0 GAF domain Peptidase_S39 PF02122.15 EGR34729.1 - 0.15 11.6 0.1 0.29 10.6 0.1 1.5 1 0 0 1 1 1 0 Peptidase S39 ArlS_N PF18719.1 EGR34729.1 - 3.2 8.0 21.9 58 3.9 0.5 3.9 2 2 1 3 3 3 0 ArlS sensor domain DUF1077 PF06417.12 EGR34731.1 - 3.2e-12 46.5 3.1 4.1e-12 46.1 3.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) SARA PF11409.8 EGR34731.1 - 0.067 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Smad anchor for receptor activation (SARA) DSPc PF00782.20 EGR34732.1 - 8.2e-14 51.6 0.0 8.2e-14 51.6 0.0 5.2 3 1 2 6 6 6 1 Dual specificity phosphatase, catalytic domain Glucos_trans_II PF14264.6 EGR34732.1 - 0.0073 15.7 13.2 0.0073 15.7 13.2 2.0 2 0 0 2 2 2 1 Glucosyl transferase GtrII zf-B_box PF00643.24 EGR34733.1 - 0.00014 21.9 16.5 0.0011 19.0 6.3 2.6 3 0 0 3 3 3 2 B-box zinc finger 3-PAP PF12578.8 EGR34733.1 - 0.081 12.7 1.3 0.17 11.6 1.3 1.5 1 0 0 1 1 1 0 Myotubularin-associated protein Ku PF02735.16 EGR34734.1 - 2.3e-14 53.6 0.1 2.3e-14 53.6 0.1 1.9 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.14 EGR34734.1 - 5e-11 43.2 7.7 1e-10 42.1 7.7 1.6 1 1 0 1 1 1 1 Ku70/Ku80 C-terminal arm WD40 PF00400.32 EGR34735.1 - 9.5e-27 92.7 8.3 1.9e-06 28.5 0.1 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR34735.1 - 3e-14 53.1 6.9 8.2e-06 26.0 0.1 4.4 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGR34735.1 - 7e-09 35.8 4.5 7e-05 22.8 0.1 3.1 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A DAO PF01266.24 EGR34736.1 - 9.8e-16 58.3 0.0 1e-11 45.0 0.0 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGR34736.1 - 1.1e-07 31.4 0.0 1.7e-07 30.8 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGR34736.1 - 4.4e-05 22.7 0.0 7.7e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EGR34736.1 - 9.8e-05 21.2 0.1 0.0002 20.2 0.1 1.5 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 EGR34736.1 - 0.00011 22.4 0.2 0.00026 21.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 EGR34736.1 - 0.00024 20.3 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EGR34736.1 - 0.0077 15.5 0.0 0.014 14.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 EGR34736.1 - 0.012 15.2 0.2 0.021 14.4 0.2 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EGR34736.1 - 0.014 15.3 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 EGR34736.1 - 0.027 15.0 0.4 0.16 12.5 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EGR34736.1 - 0.037 14.5 0.0 0.07 13.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF604 PF04646.12 EGR34736.1 - 0.041 13.3 0.9 0.07 12.5 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF604 FAD_binding_3 PF01494.19 EGR34736.1 - 0.093 12.0 0.0 0.19 10.9 0.0 1.5 2 0 0 2 2 2 0 FAD binding domain Thi4 PF01946.17 EGR34736.1 - 0.12 11.7 0.1 0.22 10.7 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 EGR34736.1 - 0.15 11.4 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase cobW PF02492.19 EGR34737.1 - 7.7e-22 77.7 0.0 1.1e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGR34737.1 - 9.3e-08 31.9 0.0 1.5e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RIH_assoc PF08454.11 EGR34738.1 - 1e-15 57.4 13.7 1e-15 57.4 13.7 7.5 6 3 0 6 6 6 1 RyR and IP3R Homology associated DUF4834 PF16118.5 EGR34739.1 - 0.0057 17.6 4.5 0.0057 17.6 4.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) Secretin_N_2 PF07655.13 EGR34739.1 - 0.023 15.3 5.3 0.033 14.7 5.3 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Neur_chan_memb PF02932.16 EGR34739.1 - 0.063 13.3 0.2 0.076 13.1 0.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ASC PF00858.24 EGR34739.1 - 0.21 10.5 9.7 0.24 10.3 9.7 1.2 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel Menin PF05053.13 EGR34739.1 - 5.6 5.2 8.8 6.5 5.0 8.8 1.0 1 0 0 1 1 1 0 Menin Peptidase_S49_N PF08496.10 EGR34739.1 - 6.4 6.8 10.6 0.61 10.1 5.4 1.8 2 0 0 2 2 2 0 Peptidase family S49 N-terminal tRNA-synt_1 PF00133.22 EGR34740.1 - 9.6e-193 641.7 0.4 1.1e-191 638.2 0.4 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGR34740.1 - 1.2e-35 122.8 0.8 3.4e-35 121.3 0.8 1.9 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGR34740.1 - 1.2e-11 44.0 7.5 2.9e-06 26.3 0.1 4.8 4 2 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EGR34740.1 - 9.7e-07 28.5 0.1 0.00021 20.9 0.0 2.9 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 EGR34740.1 - 1.6e-06 28.3 7.5 4.6e-06 26.8 7.5 1.9 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1b PF00579.25 EGR34740.1 - 0.0026 17.1 0.3 0.014 14.7 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (W and Y) CAP18_C PF12153.8 EGR34740.1 - 0.024 14.5 0.0 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 LPS binding domain of CAP18 (C terminal) tRNA-synt_1e PF01406.19 EGR34740.1 - 0.082 12.2 4.3 1.4 8.2 0.0 3.3 4 0 0 4 4 4 0 tRNA synthetases class I (C) catalytic domain HSP70 PF00012.20 EGR34741.1 - 1.4e-42 145.7 0.0 2e-42 145.2 0.0 1.1 1 0 0 1 1 1 1 Hsp70 protein E1-E2_ATPase PF00122.20 EGR34742.1 - 2.5e-52 177.0 0.2 9e-52 175.2 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGR34742.1 - 1.1e-51 175.1 0.7 1.1e-51 175.1 0.7 1.7 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGR34742.1 - 2.8e-22 80.1 0.0 1.3e-21 77.8 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGR34742.1 - 1.1e-17 63.5 0.4 2.3e-17 62.4 0.4 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGR34742.1 - 2.3e-17 62.8 0.1 5.1e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGR34742.1 - 0.00037 20.3 7.9 0.00065 19.5 1.1 2.8 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGR34742.1 - 0.0045 17.4 0.0 0.015 15.7 0.0 2.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Intein_splicing PF14890.6 EGR34742.1 - 0.062 13.2 0.1 0.56 10.2 0.1 2.4 1 1 0 1 1 1 0 Intein splicing domain MIEAP PF16026.5 EGR34742.1 - 0.16 12.1 0.0 0.44 10.7 0.0 1.7 1 0 0 1 1 1 0 Mitochondria-eating protein UFC1 PF08694.11 EGR34743.1 - 1.6e-81 271.5 0.2 1.8e-81 271.3 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 EGR34743.1 - 0.0042 16.7 0.1 0.0063 16.2 0.1 1.4 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Rep_fac-A_3 PF08661.11 EGR34744.1 - 1.5e-09 38.2 0.7 2e-09 37.7 0.7 1.3 1 1 0 1 1 1 1 Replication factor A protein 3 DUF4431 PF14485.6 EGR34744.1 - 0.029 14.1 0.3 1.3 8.8 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4431) PDEase_I PF00233.19 EGR34747.1 - 2.2e-31 109.4 0.0 2.6e-31 109.2 0.0 1.0 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I PF00233.19 EGR34748.1 - 1.1e-36 126.8 4.0 1.1e-36 126.8 4.0 2.4 2 1 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Ion_trans PF00520.31 EGR34748.1 - 5.3e-10 39.0 19.8 9.6e-10 38.1 19.8 1.4 1 0 0 1 1 1 1 Ion transport protein TTL PF03133.15 EGR34749.1 - 4.2e-51 173.8 18.7 1.1e-50 172.4 18.7 1.7 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGR34749.1 - 4.8e-09 35.8 2.4 4.3e-06 26.2 0.0 2.5 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGR34749.1 - 0.0016 17.7 1.0 0.16 11.2 0.0 2.8 2 1 1 3 3 3 2 Sugar-transfer associated ATP-grasp MACPF PF01823.19 EGR34750.1 - 7.1e-26 91.6 0.5 1.7e-25 90.4 0.5 1.7 1 0 0 1 1 1 1 MAC/Perforin domain RicinB_lectin_2 PF14200.6 EGR34750.1 - 6.6e-10 39.6 1.0 4.3e-05 24.2 0.0 3.3 2 2 2 4 4 4 3 Ricin-type beta-trefoil lectin domain-like Ricin_B_lectin PF00652.22 EGR34750.1 - 0.00073 19.8 0.7 0.0016 18.7 0.7 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Glyco_hydro_20 PF00728.22 EGR34752.1 - 2e-54 185.3 0.4 2e-54 185.3 0.4 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EGR34752.1 - 7.4e-13 49.3 3.2 1.3e-12 48.5 3.2 1.4 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EGR34752.1 - 0.00051 20.8 2.9 0.003 18.3 2.9 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 DUF1635 PF07795.11 EGR34752.1 - 0.046 13.6 3.0 0.077 12.8 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) Arteri_Gl PF00951.18 EGR34755.1 - 0.2 11.4 5.0 0.3 10.9 5.0 1.3 1 0 0 1 1 1 0 Arterivirus GL envelope glycoprotein CLP1_N PF16573.5 EGR34757.1 - 3.4e-22 78.4 0.2 1.9e-21 76.1 0.1 1.9 2 0 0 2 2 2 1 N-terminal beta-sandwich domain of polyadenylation factor CLP1_P PF16575.5 EGR34757.1 - 3.6e-11 43.2 0.1 5.6e-11 42.6 0.1 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop ATP_bind_1 PF03029.17 EGR34757.1 - 0.0038 17.1 0.3 0.0072 16.1 0.0 1.5 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein G-alpha PF00503.20 EGR34757.1 - 0.0059 15.8 0.0 0.0092 15.2 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit CbiA PF01656.23 EGR34757.1 - 0.016 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FtsK_SpoIIIE PF01580.18 EGR34757.1 - 0.043 13.2 0.0 0.061 12.7 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_24 PF13479.6 EGR34757.1 - 0.058 13.1 0.0 0.096 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EGR34757.1 - 0.062 12.6 0.0 0.089 12.1 0.0 1.3 1 0 0 1 1 1 0 KaiC DUF4947 PF16305.5 EGR34757.1 - 0.069 13.2 0.0 0.095 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4947) TniB PF05621.11 EGR34757.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_31 PF13614.6 EGR34757.1 - 0.15 12.0 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGR34757.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mitoc_mL59 PF18126.1 EGR34758.1 - 0.00031 21.0 2.2 0.00031 21.0 2.2 1.8 2 0 0 2 2 2 1 Mitochondrial ribosomal protein mL59 DUF3319 PF11782.8 EGR34758.1 - 0.028 14.4 0.0 0.055 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3319) DUF724 PF05266.14 EGR34758.1 - 0.17 11.7 7.3 0.28 11.0 7.2 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Vps5 PF09325.10 EGR34758.1 - 0.63 9.5 7.3 0.17 11.4 4.0 1.6 2 0 0 2 2 2 0 Vps5 C terminal like GAT PF03127.14 EGR34760.1 - 0.12 12.6 4.9 0.48 10.8 1.0 2.9 2 0 0 2 2 2 0 GAT domain EMI PF07546.13 EGR34760.1 - 0.21 12.4 3.0 4 8.3 0.5 3.0 2 0 0 2 2 2 0 EMI domain DUF948 PF06103.11 EGR34760.1 - 0.48 10.7 2.3 3 8.2 0.1 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Pyr_redox_2 PF07992.14 EGR34762.1 - 5.2e-62 209.7 0.9 9.8e-61 205.5 0.9 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGR34762.1 - 2.8e-37 127.3 0.8 8.9e-37 125.7 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGR34762.1 - 1.7e-19 70.2 1.8 2.1e-18 66.6 0.3 2.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGR34762.1 - 3.1e-09 36.5 3.2 4.1e-08 32.8 0.4 3.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGR34762.1 - 0.00011 21.5 0.1 0.0037 16.5 0.0 2.7 2 1 2 4 4 4 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 EGR34762.1 - 0.0008 18.8 0.7 0.061 12.6 0.0 3.1 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 EGR34762.1 - 0.0016 17.9 5.2 0.32 10.3 5.5 3.0 2 1 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGR34762.1 - 0.0025 16.6 4.3 9.6 4.8 0.2 4.3 4 0 0 4 4 4 1 HI0933-like protein NAD_binding_8 PF13450.6 EGR34762.1 - 0.027 14.7 5.3 1.5 9.1 0.0 3.2 2 1 0 2 2 2 0 NAD(P)-binding Rossmann-like domain 3HCDH_N PF02737.18 EGR34762.1 - 0.036 14.0 0.5 0.11 12.4 0.1 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.12 EGR34762.1 - 0.041 12.9 0.2 5.5 5.9 0.0 2.3 2 0 0 2 2 2 0 Lycopene cyclase protein UDPG_MGDP_dh_N PF03721.14 EGR34762.1 - 0.042 13.4 0.3 0.093 12.3 0.3 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_2 PF00890.24 EGR34762.1 - 0.052 12.6 14.7 0.33 10.0 0.0 4.8 3 2 1 4 4 4 0 FAD binding domain FAD_binding_3 PF01494.19 EGR34762.1 - 0.068 12.4 0.8 5.5 6.1 0.3 2.6 2 1 1 3 3 3 0 FAD binding domain 2-Hacid_dh_C PF02826.19 EGR34762.1 - 0.11 11.8 0.3 0.37 10.1 0.1 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GIDA PF01134.22 EGR34762.1 - 1.3 8.0 14.1 7.8 5.5 7.1 3.8 2 2 0 3 3 3 0 Glucose inhibited division protein A Sec7_N PF12783.7 EGR34763.1 - 6.5e-33 113.9 10.5 6.5e-33 113.9 10.5 7.8 6 1 1 8 8 8 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Sec7 PF01369.20 EGR34763.1 - 1.1e-26 93.7 1.2 6.1e-24 84.7 0.1 6.7 7 2 1 8 8 8 2 Sec7 domain DUF1981 PF09324.10 EGR34763.1 - 1.7e-20 72.7 4.6 1.7e-20 72.7 4.6 7.9 9 0 0 9 9 9 2 Domain of unknown function (DUF1981) FAST_2 PF08368.12 EGR34763.1 - 0.48 11.2 6.3 0.87 10.4 0.2 3.8 3 0 0 3 3 3 0 FAST kinase-like protein, subdomain 2 RTP1_C1 PF10363.9 EGR34763.1 - 0.54 10.5 11.8 0.94 9.7 0.9 3.8 3 0 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 FANCI_HD1 PF14679.6 EGR34763.1 - 2 8.5 9.6 0.11 12.5 1.1 3.6 3 0 0 3 3 3 0 FANCI helical domain 1 Thioredoxin PF00085.20 EGR34764.1 - 5.6e-22 77.7 0.0 9.3e-22 77.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin TMEM154 PF15102.6 EGR34764.1 - 0.00037 20.4 0.6 0.078 12.9 0.2 2.2 2 0 0 2 2 2 1 TMEM154 protein family Thioredoxin_2 PF13098.6 EGR34764.1 - 0.00073 20.0 0.1 0.0017 18.8 0.1 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain EphA2_TM PF14575.6 EGR34764.1 - 0.0012 19.6 0.1 0.03 15.2 0.0 2.2 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain DUF5373 PF17343.2 EGR34764.1 - 0.0047 16.8 0.4 0.024 14.5 0.0 1.9 2 0 0 2 2 2 1 Family of unknown function (DUF5373) Shisa PF13908.6 EGR34764.1 - 0.0067 16.7 0.1 0.012 15.9 0.1 1.5 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator PAG PF15347.6 EGR34764.1 - 0.0093 15.0 0.3 0.014 14.4 0.3 1.2 1 0 0 1 1 1 1 Phosphoprotein associated with glycosphingolipid-enriched ETRAMP PF09716.10 EGR34764.1 - 0.011 15.8 0.2 0.11 12.6 0.1 2.2 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Sigma_reg_N PF13800.6 EGR34764.1 - 0.011 16.0 1.5 0.33 11.3 0.0 2.4 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Thioredoxin_9 PF14595.6 EGR34764.1 - 0.021 14.6 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin RITA PF17066.5 EGR34764.1 - 0.04 13.5 0.0 0.077 12.6 0.0 1.4 1 0 0 1 1 1 0 RBPJ-interacting and tubulin associated protein Tmemb_9 PF05434.11 EGR34764.1 - 0.044 13.7 0.0 0.098 12.5 0.0 1.7 1 0 0 1 1 1 0 TMEM9 AhpC-TSA PF00578.21 EGR34764.1 - 0.082 12.8 0.1 0.24 11.3 0.1 1.8 1 1 1 2 2 2 0 AhpC/TSA family Thioredoxin_8 PF13905.6 EGR34764.1 - 0.096 13.0 0.1 1.5 9.2 0.0 2.5 1 1 2 3 3 3 0 Thioredoxin-like ODV-E18 PF10717.9 EGR34764.1 - 0.14 12.0 3.2 0.13 12.2 0.4 2.1 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF3139 PF11337.8 EGR34764.1 - 0.17 12.5 7.5 0.71 10.6 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3139) zf-LITAF-like PF10601.9 EGR34764.1 - 0.19 12.0 2.6 0.88 9.9 0.5 2.3 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Baculo_11_kDa PF06143.11 EGR34764.1 - 0.27 10.8 5.5 0.52 9.9 0.3 2.3 2 0 0 2 2 2 0 Baculovirus 11 kDa family PsiE PF06146.12 EGR34767.1 - 0.07 13.5 0.8 0.93 9.9 0.1 2.3 2 0 0 2 2 2 0 Phosphate-starvation-inducible E Ion_trans_2 PF07885.16 EGR34768.1 - 1.3e-11 44.3 4.8 6.3e-11 42.1 4.8 2.3 1 0 0 1 1 1 1 Ion channel cNMP_binding PF00027.29 EGR34768.1 - 0.0095 16.0 0.1 0.022 14.8 0.1 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Lig_chan PF00060.26 EGR34768.1 - 0.12 12.2 1.5 0.51 10.2 1.5 2.1 1 0 0 1 1 1 0 Ligand-gated ion channel G10 PF01125.17 EGR34770.1 - 4.4e-65 217.9 9.5 4.9e-65 217.8 9.5 1.0 1 0 0 1 1 1 1 G10 protein cNMP_binding PF00027.29 EGR34771.1 - 0.00017 21.6 0.0 0.079 13.0 0.0 2.8 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain KxDL PF10241.9 EGR34771.1 - 0.05 13.9 0.8 0.05 13.9 0.8 4.0 3 1 1 4 4 4 0 Uncharacterized conserved protein Octopine_DH PF02317.17 EGR34771.1 - 0.26 11.4 1.9 1.4 9.0 0.4 2.5 2 0 0 2 2 2 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Pep3_Vps18 PF05131.14 EGR34772.1 - 6.4e-19 68.2 13.5 4.6e-16 59.0 7.3 4.7 3 1 0 3 3 3 1 Pep3/Vps18/deep orange family Vps39_2 PF10367.9 EGR34772.1 - 2.4e-06 27.9 2.6 2.4e-06 27.9 2.6 3.6 3 1 1 4 4 4 1 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 EGR34772.1 - 0.00027 20.8 5.1 0.00085 19.2 5.1 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 EGR34772.1 - 0.0088 15.8 5.3 0.025 14.3 5.3 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EGR34772.1 - 0.0096 15.9 2.7 0.033 14.2 2.7 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGR34772.1 - 0.01 15.6 5.8 0.031 14.1 5.8 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGR34772.1 - 0.13 12.6 5.4 0.43 11.0 5.4 1.9 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 EGR34772.1 - 0.22 11.4 5.3 0.85 9.5 5.3 2.1 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGR34772.1 - 0.28 11.5 4.0 1.1 9.6 4.0 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF4407 PF14362.6 EGR34772.1 - 1.9 7.8 7.1 0.38 10.0 1.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF2076 PF09849.9 EGR34772.1 - 2.2 8.2 6.0 0.45 10.5 0.9 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) LPP PF04728.13 EGR34772.1 - 2.8 8.4 12.1 2.8 8.4 1.0 3.3 3 0 0 3 3 2 0 Lipoprotein leucine-zipper Zn_ribbon_17 PF17120.5 EGR34772.1 - 3.9 7.2 5.3 3.6 7.3 2.9 2.2 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type NUDIX PF00293.28 EGR34773.1 - 1.9e-16 60.3 0.0 2.3e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain UPF0236 PF06782.11 EGR34775.1 - 0.032 12.9 0.4 0.036 12.7 0.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0236) Siah-Interact_N PF09032.11 EGR34776.1 - 3.2 8.1 6.8 1.8 8.9 0.8 2.1 2 0 0 2 2 2 0 Siah interacting protein, N terminal T_Ag_DNA_bind PF02217.16 EGR34779.1 - 0.11 13.1 6.4 0.13 12.8 6.4 1.3 1 0 0 1 1 1 0 Origin of replication binding protein Ephrin_rec_like PF07699.13 EGR34780.1 - 0.00027 20.6 7.6 0.00027 20.6 7.6 9.9 6 4 4 10 10 10 3 Putative ephrin-receptor like Fer4_9 PF13187.6 EGR34780.1 - 0.002 18.3 46.9 1 9.5 3.1 7.7 3 3 4 7 7 7 4 4Fe-4S dicluster domain Antistasin PF02822.14 EGR34780.1 - 0.0073 16.9 7.2 5.5 7.7 0.1 6.3 6 0 0 6 6 6 1 Antistasin family GF_recep_IV PF14843.6 EGR34780.1 - 2.4 8.0 51.5 0.08 12.8 1.5 5.2 3 2 1 4 4 4 0 Growth factor receptor domain IV TauD PF02668.16 EGR34781.1 - 7.7e-08 32.5 0.1 3.5e-06 27.0 0.1 2.3 1 1 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family UPF0004 PF00919.20 EGR34782.1 - 5.5e-22 77.6 0.1 1.2e-21 76.5 0.1 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 EGR34782.1 - 1.1e-19 71.4 0.4 2.8e-19 70.1 0.4 1.7 2 0 0 2 2 2 1 Radical SAM superfamily TRAM PF01938.20 EGR34782.1 - 0.051 13.6 0.6 0.29 11.2 0.0 2.3 2 0 0 2 2 2 0 TRAM domain DUF3096 PF11295.8 EGR34782.1 - 7.5 6.3 6.5 1.5 8.6 2.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3096) PI3_PI4_kinase PF00454.27 EGR34783.1 - 1.8e-27 96.8 1.1 4.6e-25 88.9 1.1 2.5 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF5494 PF17598.2 EGR34783.1 - 0.48 10.6 0.1 0.48 10.6 0.1 2.2 3 0 0 3 3 3 0 Family of unknown function (DUF5494) Ldh_1_N PF00056.23 EGR34785.1 - 2.4e-33 115.2 0.0 4.6e-33 114.3 0.0 1.5 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 EGR34785.1 - 2.5e-32 112.1 0.0 3.5e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Glyco_hydro_3_C PF01915.22 EGR34785.1 - 0.006 16.6 0.0 0.42 10.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 3 C-terminal domain WD40 PF00400.32 EGR34786.1 - 3.6e-12 46.6 10.3 0.0013 19.5 0.2 5.6 6 1 0 6 6 6 3 WD domain, G-beta repeat RabGAP-TBC PF00566.18 EGR34789.1 - 1.9e-41 142.1 14.5 1.9e-41 142.1 14.5 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Deltameth_res PF16020.5 EGR34789.1 - 0.44 10.4 2.5 0.4 10.6 0.4 2.0 2 0 0 2 2 2 0 Deltamethrin resistance Choline_kinase PF01633.20 EGR34791.1 - 2.3e-10 40.5 0.2 1.5e-09 37.8 0.0 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase Pkinase PF00069.25 EGR34792.1 - 1.6e-63 214.5 2.5 1.6e-63 214.5 2.5 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34792.1 - 1.6e-38 132.5 0.2 2.6e-38 131.8 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGR34792.1 - 0.00043 19.7 0.8 0.0012 18.2 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF4506 PF14958.6 EGR34792.1 - 0.0048 16.4 0.3 0.013 15.0 0.3 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4506) Dna2 PF08696.11 EGR34792.1 - 0.014 15.2 2.5 0.014 15.2 2.5 2.4 2 0 0 2 2 2 0 DNA replication factor Dna2 WD40 PF00400.32 EGR34794.1 - 3.2e-13 49.9 4.8 0.00078 20.2 0.3 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR34794.1 - 0.0025 18.1 0.2 3.2 8.1 0.0 4.5 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain HELP PF03451.14 EGR34794.1 - 0.069 13.0 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 HELP motif MitMem_reg PF13012.6 EGR34795.1 - 5.4e-31 107.3 0.8 1e-30 106.4 0.8 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EGR34795.1 - 6.5e-29 100.3 1.8 2.5e-28 98.4 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PEX11 PF05648.14 EGR34795.1 - 0.11 11.9 1.0 0.21 11.0 1.0 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Peptidase_S49_N PF08496.10 EGR34795.1 - 0.14 12.2 5.9 0.34 11.0 5.9 1.7 1 0 0 1 1 1 0 Peptidase family S49 N-terminal OAD_gamma PF04277.13 EGR34795.1 - 0.16 12.6 0.3 0.33 11.6 0.3 1.5 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Pkinase PF00069.25 EGR34797.1 - 4.8e-71 239.2 0.2 6.2e-71 238.8 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34797.1 - 1.5e-37 129.3 0.0 2e-37 128.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR34797.1 - 5.2e-05 22.4 5.1 0.00014 21.0 5.1 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGR34797.1 - 0.0034 16.2 0.5 0.067 12.0 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGR34797.1 - 0.046 13.6 0.0 0.081 12.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EGR34797.1 - 0.052 13.1 2.7 0.061 12.8 0.1 2.0 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL HEPN PF05168.14 EGR34798.1 - 0.0072 16.4 0.2 0.014 15.5 0.1 1.4 1 1 0 1 1 1 1 HEPN domain Peptidase_C1 PF00112.23 EGR34799.1 - 1.2e-38 133.4 2.8 1.2e-38 133.4 2.8 2.6 2 1 1 3 3 3 1 Papain family cysteine protease CathepsinC_exc PF08773.11 EGR34799.1 - 1e-18 67.7 11.3 6.3e-17 62.0 11.3 2.7 1 1 0 1 1 1 1 Cathepsin C exclusion domain Propeptide_C1 PF08127.13 EGR34799.1 - 0.07 13.0 0.8 0.38 10.7 0.8 2.3 1 0 0 1 1 1 0 Peptidase family C1 propeptide DUF1664 PF07889.12 EGR34799.1 - 1.2 9.2 6.3 0.35 10.9 3.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Proteasome PF00227.26 EGR34800.1 - 5.4e-47 159.8 0.8 6.6e-47 159.5 0.8 1.1 1 0 0 1 1 1 1 Proteasome subunit UDPG_MGDP_dh_N PF03721.14 EGR34800.1 - 0.032 13.8 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AAA_7 PF12775.7 EGR34800.1 - 0.049 13.1 0.0 0.39 10.2 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region Usp PF00582.26 EGR34801.1 - 3.2e-13 50.4 0.0 1.2e-07 32.3 0.0 2.9 2 1 0 2 2 2 2 Universal stress protein family RNA_pol_Rpb2_6 PF00562.28 EGR34802.1 - 3.7e-42 144.8 0.0 8.6e-42 143.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGR34802.1 - 3.9e-30 104.9 0.4 7.9e-30 103.9 0.4 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_4 PF04566.13 EGR34802.1 - 2.7e-21 75.6 0.1 6.9e-21 74.3 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.16 EGR34802.1 - 3.6e-20 71.9 0.0 8e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_2 PF04561.14 EGR34802.1 - 5.2e-19 68.6 1.0 5.2e-19 68.6 1.0 3.3 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_5 PF04567.17 EGR34802.1 - 7.7e-11 42.4 1.0 3.1e-10 40.5 1.0 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 RCC1 PF00415.18 EGR34803.1 - 3.1e-63 210.2 5.8 1e-11 45.3 0.1 6.5 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGR34803.1 - 1e-37 127.2 21.4 2.4e-10 39.9 1.1 6.5 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Pyr_excise PF03013.14 EGR34803.1 - 0.01 15.8 0.1 0.82 9.7 0.1 2.4 1 1 0 1 1 1 0 Pyrimidine dimer DNA glycosylase Methyltranf_PUA PF13636.6 EGR34803.1 - 0.04 13.9 0.7 0.31 11.1 0.0 2.6 3 0 0 3 3 3 0 RNA-binding PUA-like domain of methyltransferase RsmF Dynamin_M PF01031.20 EGR34804.1 - 5e-79 265.5 2.4 5e-79 265.5 2.4 2.0 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 EGR34804.1 - 1.8e-47 161.5 0.0 1.8e-47 161.5 0.0 3.8 3 1 0 3 3 3 1 Dynamin family GED PF02212.18 EGR34804.1 - 2.7e-12 46.6 5.1 1.7e-10 40.9 0.1 3.4 3 0 0 3 3 3 2 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGR34804.1 - 4e-05 23.7 0.1 0.00026 21.0 0.0 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGR34804.1 - 0.045 13.3 0.1 7 6.2 0.1 2.4 2 0 0 2 2 2 0 Ferrous iron transport protein B SUIM_assoc PF16619.5 EGR34804.1 - 0.19 11.8 0.0 0.19 11.8 0.0 7.2 1 1 4 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 ABC_tran PF00005.27 EGR34804.1 - 0.4 11.2 0.0 0.4 11.2 0.0 3.9 3 1 0 3 3 3 0 ABC transporter RTX_C PF08339.10 EGR34804.1 - 1.6 8.8 9.0 0.12 12.4 2.9 2.3 2 0 0 2 2 2 0 RTX C-terminal domain TFIIA PF03153.13 EGR34804.1 - 2.2 8.2 76.5 0.74 9.8 69.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PITH PF06201.13 EGR34805.1 - 3.8e-33 114.9 5.1 4.5e-33 114.6 5.1 1.1 1 0 0 1 1 1 1 PITH domain WD40 PF00400.32 EGR34806.1 - 2.4e-15 56.7 7.2 4e-06 27.5 1.0 4.5 3 1 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR34806.1 - 5.6e-05 23.4 1.4 0.0008 19.7 0.1 2.8 1 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGR34807.1 - 3.4e-23 81.5 3.3 7.5e-06 26.6 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR34807.1 - 2.1e-07 31.1 0.0 0.026 14.8 0.0 3.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGR34807.1 - 0.0022 17.4 4.1 0.12 11.7 1.8 3.0 2 1 0 2 2 2 2 WD40-like domain POLO_box PF00659.18 EGR34807.1 - 0.0078 16.4 0.5 2.7 8.2 0.1 2.7 2 0 0 2 2 2 2 POLO box duplicated region TMEM237 PF15383.6 EGR34807.1 - 0.33 10.0 1.6 0.59 9.2 1.6 1.3 1 0 0 1 1 1 0 Transmembrane protein 237 SprA-related PF12118.8 EGR34807.1 - 1.7 7.7 4.6 2.4 7.2 4.6 1.1 1 0 0 1 1 1 0 SprA-related family PHF5 PF03660.14 EGR34808.1 - 3.1e-50 168.7 13.7 3.5e-50 168.6 13.7 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 EGR34808.1 - 0.2 9.5 6.6 0.033 12.1 3.5 1.2 1 1 0 1 1 1 0 DNA polymerase II large subunit DP2 PAS_9 PF13426.7 EGR34809.1 - 0.034 14.4 4.7 0.32 11.3 0.0 4.0 3 1 1 4 4 4 0 PAS domain DUF4637 PF15470.6 EGR34809.1 - 0.041 13.6 0.2 0.041 13.6 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4637) DUF2403 PF10290.9 EGR34809.1 - 0.055 13.9 0.4 0.17 12.3 0.0 2.0 2 0 0 2 2 2 0 Glycine-rich protein domain (DUF2403) Pepdidase_M14_N PF18027.1 EGR34809.1 - 0.16 12.4 1.7 0.91 9.9 0.6 2.8 2 0 0 2 2 2 0 Cytosolic carboxypeptidase N-terminal domain Thioredoxin_8 PF13905.6 EGR34809.1 - 0.8 10.1 6.4 0.24 11.7 0.8 3.2 2 1 0 2 2 2 0 Thioredoxin-like SF-assemblin PF06705.11 EGR34810.1 - 0.00011 21.6 15.5 0.041 13.2 15.4 2.0 1 1 0 1 1 1 1 SF-assemblin/beta giardin Gly_acyl_tr_N PF06021.11 EGR34810.1 - 0.011 15.9 0.9 0.013 15.6 0.9 1.1 1 0 0 1 1 1 0 Aralkyl acyl-CoA:amino acid N-acyltransferase FAA_hydrolase_N PF09298.11 EGR34810.1 - 0.11 12.6 1.6 0.38 11.0 1.6 1.8 1 1 0 1 1 1 0 Fumarylacetoacetase N-terminal DUF3450 PF11932.8 EGR34810.1 - 3.3 6.9 9.1 3.8 6.7 9.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Ion_trans PF00520.31 EGR34811.1 - 5.2e-31 107.7 44.5 1.2e-21 77.1 37.1 2.7 2 1 0 2 2 2 2 Ion transport protein Ras PF00071.22 EGR34812.1 - 3.4e-63 212.1 2.9 4e-63 211.9 2.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGR34812.1 - 1.8e-35 121.7 2.0 3.4e-35 120.8 2.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGR34812.1 - 7.9e-17 61.3 1.4 1e-16 60.9 1.4 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGR34812.1 - 1.9e-05 24.1 3.8 0.00026 20.4 3.8 2.0 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGR34812.1 - 3.3e-05 23.4 0.6 4.4e-05 23.0 0.6 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EGR34812.1 - 8.5e-05 22.5 1.0 0.046 13.6 0.1 2.3 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGR34812.1 - 0.00018 21.6 0.6 0.00036 20.6 0.6 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGR34812.1 - 0.00073 19.1 0.3 0.0035 16.9 0.3 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B TniB PF05621.11 EGR34812.1 - 0.0035 16.8 0.0 0.0088 15.5 0.0 1.6 1 0 0 1 1 1 1 Bacterial TniB protein Septin PF00735.18 EGR34812.1 - 0.011 15.0 0.9 0.011 15.0 0.9 1.8 1 1 1 2 2 2 0 Septin GTP_EFTU PF00009.27 EGR34812.1 - 0.024 14.2 1.8 0.037 13.6 0.8 1.7 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 EGR34812.1 - 0.063 13.0 1.8 0.058 13.1 0.6 1.7 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGR34812.1 - 0.074 13.4 0.0 0.11 12.9 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EGR34812.1 - 0.091 13.3 1.7 0.16 12.5 1.7 1.6 1 1 0 1 1 1 0 ABC transporter Mito_carr PF00153.27 EGR34813.1 - 3.9e-12 45.9 0.3 6.3e-07 29.2 0.0 3.1 2 1 1 3 3 3 2 Mitochondrial carrier protein Selenoprotein_S PF06936.11 EGR34813.1 - 0.21 11.4 0.0 0.39 10.5 0.0 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) DHHC PF01529.20 EGR34814.1 - 9.8e-19 67.8 19.3 9.8e-19 67.8 19.3 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase OST_P2 PF18235.1 EGR34814.1 - 0.019 14.9 0.8 0.035 14.0 0.8 1.4 1 0 0 1 1 1 0 Oligosaccharyltransferase Peripheral 2 domain SieB PF14163.6 EGR34814.1 - 3.6 7.1 10.7 0.072 12.6 2.7 2.1 2 0 0 2 2 2 0 Super-infection exclusion protein B LRR_4 PF12799.7 EGR34815.1 - 3.1e-13 49.7 29.8 1.9e-05 24.9 3.1 3.6 1 1 4 5 5 5 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGR34815.1 - 5.7e-10 39.0 5.8 1e-07 31.7 0.3 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 EGR34815.1 - 4.5e-05 23.1 11.4 0.02 14.7 4.5 3.6 1 1 2 3 3 3 3 Leucine rich repeat TTRAP PF14203.6 EGR34815.1 - 0.19 11.7 0.8 2.7 8.0 0.0 3.0 3 0 0 3 3 3 0 Putative tranposon-transfer assisting protein LRR_1 PF00560.33 EGR34815.1 - 5.4 8.0 10.4 69 4.6 0.1 4.5 3 1 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 EGR34815.1 - 6 7.2 8.6 23 5.4 0.1 4.1 4 0 0 4 4 4 0 Leucine Rich repeat Guanylate_cyc PF00211.20 EGR34816.1 - 2.6e-15 56.5 0.1 5.5e-15 55.5 0.1 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain BSP_II PF05432.11 EGR34816.1 - 0.063 13.0 9.2 0.098 12.3 9.2 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF4407 PF14362.6 EGR34816.1 - 9.2 5.5 10.2 17 4.7 10.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ABC_tran PF00005.27 EGR34817.1 - 1.1e-46 158.8 12.2 1.6e-27 96.7 0.1 4.0 5 0 0 5 5 5 2 ABC transporter ABC_membrane PF00664.23 EGR34817.1 - 1.1e-14 54.7 29.1 2e-14 53.9 29.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EGR34817.1 - 6.4e-09 35.6 14.7 0.0036 16.8 5.3 4.4 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGR34817.1 - 1.1e-08 35.3 7.5 0.096 12.5 0.1 4.9 3 2 0 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EGR34817.1 - 1.8e-05 24.8 0.1 0.017 15.2 0.1 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EGR34817.1 - 2.2e-05 24.8 2.7 0.055 13.7 0.1 3.5 3 1 0 3 3 2 2 AAA domain AAA_16 PF13191.6 EGR34817.1 - 8.7e-05 23.0 0.0 0.43 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGR34817.1 - 0.00023 21.1 0.1 0.88 9.5 0.0 3.7 3 0 0 3 3 3 2 RsgA GTPase AAA_7 PF12775.7 EGR34817.1 - 0.00053 19.6 0.2 0.48 9.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region KAP_NTPase PF07693.14 EGR34817.1 - 0.0016 17.8 0.0 0.057 12.6 0.0 2.7 2 1 0 2 2 2 1 KAP family P-loop domain AAA_29 PF13555.6 EGR34817.1 - 0.0028 17.4 1.0 0.9 9.3 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain cobW PF02492.19 EGR34817.1 - 0.018 14.7 0.3 1.7 8.2 0.0 2.9 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EGR34817.1 - 0.018 14.8 0.1 11 5.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain DUF5507 PF17612.2 EGR34817.1 - 0.02 14.6 0.1 0.084 12.6 0.1 2.1 1 0 0 1 1 1 0 Family of unknown function (DUF5507) AAA_18 PF13238.6 EGR34817.1 - 0.023 15.3 0.4 6.1 7.4 0.0 3.0 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 EGR34817.1 - 0.031 14.3 0.2 6 6.9 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DEAD PF00270.29 EGR34817.1 - 0.036 13.8 0.3 7.2 6.3 1.7 3.4 3 2 0 3 3 3 0 DEAD/DEAH box helicase AAA_33 PF13671.6 EGR34817.1 - 0.12 12.5 0.0 20 5.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGR34817.1 - 0.14 11.4 2.6 24 4.2 0.0 3.4 3 0 0 3 3 3 0 Zeta toxin SbcCD_C PF13558.6 EGR34817.1 - 0.17 12.1 0.0 28 5.0 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.12 EGR34817.1 - 0.27 11.1 3.4 7.9 6.4 0.0 3.2 4 0 0 4 4 3 0 NACHT domain AAA_5 PF07728.14 EGR34817.1 - 0.33 11.0 1.3 81 3.2 0.0 3.8 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) Roc PF08477.13 EGR34817.1 - 0.7 10.1 7.5 5.1 7.3 0.0 4.4 5 0 0 5 5 5 0 Ras of Complex, Roc, domain of DAPkinase DUF87 PF01935.17 EGR34817.1 - 0.9 9.6 0.0 0.9 9.6 0.0 3.8 5 0 0 5 5 4 0 Helicase HerA, central domain Dynamin_N PF00350.23 EGR34817.1 - 2.9 7.9 10.8 2.5 8.2 0.2 3.3 3 2 0 3 3 2 0 Dynamin family ABC_membrane PF00664.23 EGR34818.1 - 6.1e-16 58.9 27.1 1.2e-15 57.9 27.1 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGR34818.1 - 7.7e-16 58.9 16.5 3.2e-14 53.6 0.0 4.2 4 0 0 4 4 4 2 ABC transporter SMC_N PF02463.19 EGR34818.1 - 1.9e-09 37.3 0.0 5.1e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF1911 PF08929.10 EGR34818.1 - 5.1 7.9 11.5 16 6.3 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1911) AAA_11 PF13086.6 EGR34819.1 - 0.52 10.0 10.0 0.61 9.8 10.0 1.2 1 0 0 1 1 1 0 AAA domain CAF1C_H4-bd PF12265.8 EGR34820.1 - 1.1e-24 86.4 1.0 2.7e-24 85.2 0.3 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGR34820.1 - 8.1e-21 74.0 8.9 5.5e-06 27.0 0.4 5.8 5 0 0 5 5 5 5 WD domain, G-beta repeat AAA PF00004.29 EGR34821.1 - 1.1e-12 48.5 1.9 6e-12 46.1 0.0 2.3 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGR34821.1 - 8.3e-09 35.6 0.7 4.2e-07 30.1 0.7 2.6 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_16 PF13191.6 EGR34821.1 - 0.00034 21.0 0.0 0.00089 19.7 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 EGR34821.1 - 0.0004 20.3 0.2 0.29 11.0 0.1 2.5 1 1 1 2 2 2 2 NTPase RuvB_N PF05496.12 EGR34821.1 - 0.0016 18.2 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGR34821.1 - 0.0018 18.5 0.0 0.0066 16.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGR34821.1 - 0.0031 17.5 0.0 0.0077 16.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGR34821.1 - 0.0047 16.9 0.1 0.013 15.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 EGR34821.1 - 0.0082 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region UPF0270 PF06794.12 EGR34821.1 - 0.023 14.8 1.1 0.31 11.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0270) AAA_18 PF13238.6 EGR34821.1 - 0.037 14.6 0.5 0.1 13.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EGR34821.1 - 0.038 14.2 0.0 0.073 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGR34821.1 - 0.041 13.6 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_6 PF12774.7 EGR34821.1 - 0.047 12.7 0.0 0.083 11.8 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region RNA_helicase PF00910.22 EGR34821.1 - 0.066 13.6 0.0 0.21 12.0 0.0 2.0 1 1 0 1 1 1 0 RNA helicase AAA_19 PF13245.6 EGR34821.1 - 0.069 13.5 0.1 0.18 12.1 0.1 1.6 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGR34821.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 EGR34821.1 - 0.14 12.6 3.1 0.69 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EGR34821.1 - 0.18 11.6 8.2 1.5 8.5 8.2 2.1 1 1 0 1 1 1 0 AAA domain FCP1_C PF09309.10 EGR34821.1 - 1.6 8.5 11.1 3.2 7.6 11.1 1.4 1 0 0 1 1 1 0 FCP1, C-terminal DUSP PF06337.12 EGR34821.1 - 9.6 6.9 8.4 0.9 10.2 0.7 2.7 2 1 1 3 3 3 0 DUSP domain NARP1 PF12569.8 EGR34822.1 - 4.6e-72 243.6 18.6 4.6e-72 243.6 18.6 4.2 3 2 1 4 4 4 3 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 EGR34822.1 - 2.6e-11 42.7 11.4 5.1e-06 26.2 0.0 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGR34822.1 - 4.6e-11 43.1 4.2 0.0063 17.0 0.1 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGR34822.1 - 3.7e-09 36.6 0.0 0.00046 20.8 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGR34822.1 - 2.9e-08 33.2 1.9 0.0019 18.1 0.0 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGR34822.1 - 7.8e-08 32.2 7.1 0.021 15.2 0.0 6.8 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGR34822.1 - 1.4e-06 28.0 14.4 0.0096 16.1 0.0 7.3 7 0 0 7 7 7 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGR34822.1 - 3.1e-06 27.3 21.8 7.6e-06 26.1 0.7 5.3 5 1 1 6 6 5 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.28 EGR34822.1 - 5.3e-06 26.0 16.2 2.1e-05 24.1 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGR34822.1 - 6.9e-06 26.3 4.7 0.045 14.1 0.0 5.1 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGR34822.1 - 1.1e-05 25.0 0.7 0.00019 21.0 0.1 3.0 2 0 0 2 2 2 1 TPR repeat TPR_16 PF13432.6 EGR34822.1 - 0.00022 21.8 0.0 0.024 15.3 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGR34822.1 - 0.0023 18.0 0.0 0.024 14.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGR34822.1 - 0.0031 16.8 4.2 0.0097 15.1 0.0 3.5 1 1 3 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGR34822.1 - 0.0061 16.6 8.8 4.3 7.5 0.0 5.1 5 0 0 5 5 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 EGR34822.1 - 0.013 15.4 0.1 1.6 8.7 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat VWA PF00092.28 EGR34822.1 - 0.065 13.5 0.1 0.065 13.5 0.1 2.7 3 2 1 4 4 2 0 von Willebrand factor type A domain DUF4878 PF12870.7 EGR34822.1 - 0.28 11.5 8.8 0.11 12.8 4.7 2.6 2 1 0 2 2 1 0 Domain of unknown function (DUF4878) MIT PF04212.18 EGR34822.1 - 0.46 10.6 0.1 0.46 10.6 0.1 4.1 6 0 0 6 6 4 0 MIT (microtubule interacting and transport) domain Conotoxin PF02950.17 EGR34822.1 - 4.3 8.4 7.6 6.7 7.8 0.2 2.8 2 0 0 2 2 2 0 Conotoxin Methyltransf_11 PF08241.12 EGR34823.1 - 4.5e-15 56.1 0.0 6.3e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGR34823.1 - 4.9e-13 49.1 0.0 5.7e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGR34823.1 - 2.2e-11 44.3 0.0 3.9e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGR34823.1 - 4.7e-08 33.0 0.0 5.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGR34823.1 - 1.7e-07 31.9 0.0 2.5e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGR34823.1 - 9.6e-05 21.8 0.0 0.00013 21.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 EGR34823.1 - 0.1 12.6 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 EGR34823.1 - 0.14 11.7 0.0 0.35 10.4 0.0 1.6 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW TPMT PF05724.11 EGR34823.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.4 2 0 0 2 2 2 0 Thiopurine S-methyltransferase (TPMT) MORN PF02493.20 EGR34824.1 - 3.3e-11 42.4 19.1 0.00026 20.7 0.1 5.8 6 0 0 6 6 6 4 MORN repeat MORN PF02493.20 EGR34825.1 - 3.2e-51 168.2 58.3 1.1e-09 37.5 1.0 10.1 10 0 0 10 10 10 9 MORN repeat Pkinase PF00069.25 EGR34826.1 - 7.6e-78 261.5 0.3 8.7e-78 261.3 0.3 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34826.1 - 3.1e-38 131.5 0.1 4.3e-38 131.1 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR34826.1 - 4.3e-12 45.7 0.6 7.1e-12 44.9 0.6 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGR34826.1 - 0.00054 20.0 0.0 0.0049 16.8 0.0 1.9 1 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGR34826.1 - 0.001 18.7 0.7 0.0019 17.9 0.7 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EGR34826.1 - 0.0015 17.9 1.1 0.0083 15.5 0.2 2.2 1 1 1 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 EGR34826.1 - 0.0025 16.9 0.1 0.0052 15.9 0.0 1.5 2 0 0 2 2 2 1 Seadornavirus VP7 Kdo PF06293.14 EGR34826.1 - 0.0063 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2887 PF11103.8 EGR34827.1 - 0.013 15.6 8.5 0.017 15.2 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2887) DUF1987 PF09345.10 EGR34827.1 - 0.33 10.6 6.9 0.13 11.9 2.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) PFK PF00365.20 EGR34828.1 - 2.1e-58 197.9 0.3 3.2e-58 197.3 0.3 1.2 1 0 0 1 1 1 1 Phosphofructokinase DAGK_cat PF00781.24 EGR34828.1 - 0.0086 15.7 0.0 0.025 14.2 0.0 1.8 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 EGR34828.1 - 0.066 12.4 0.0 0.12 11.5 0.0 1.4 1 0 0 1 1 1 0 ATP-NAD kinase bZIP_1 PF00170.21 EGR34829.1 - 0.00065 19.7 1.0 0.00065 19.7 1.0 6.8 4 3 4 8 8 8 2 bZIP transcription factor DUF4200 PF13863.6 EGR34829.1 - 0.019 15.3 22.5 0.019 15.3 22.5 4.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4200) APG6_N PF17675.1 EGR34829.1 - 0.11 13.1 73.9 0.25 11.9 18.8 4.4 1 1 4 5 5 5 0 Apg6 coiled-coil region Golgin_A5 PF09787.9 EGR34829.1 - 0.57 9.6 74.9 0.39 10.1 4.2 4.1 1 1 3 4 4 4 0 Golgin subfamily A member 5 Tropomyosin_1 PF12718.7 EGR34829.1 - 2.3 8.4 68.9 0.5 10.5 9.1 5.1 1 1 3 5 5 5 0 Tropomyosin like Filament PF00038.21 EGR34829.1 - 3.4 7.2 69.7 1.3 8.5 44.1 3.3 1 1 2 3 3 3 0 Intermediate filament protein BLOC1_2 PF10046.9 EGR34829.1 - 3.5 8.0 49.8 0.069 13.5 4.3 5.3 3 2 3 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Baculo_PEP_C PF04513.12 EGR34829.1 - 3.9 7.5 26.6 0.56 10.2 1.8 4.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus FAM184 PF15665.5 EGR34829.1 - 6.7 6.4 68.5 3.9 7.2 26.0 3.4 1 1 2 3 3 3 0 Family with sequence similarity 184, A and B AAA PF00004.29 EGR34830.1 - 4.5e-13 49.8 0.5 1.1e-12 48.6 0.1 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGR34830.1 - 4.1e-10 40.3 0.0 8.8e-10 39.2 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGR34830.1 - 2.3e-09 37.6 0.3 6.3e-09 36.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_lid_10 PF17872.1 EGR34830.1 - 0.00033 20.7 1.2 0.0011 19.0 0.3 2.2 2 0 0 2 2 2 1 AAA lid domain NB-ARC PF00931.22 EGR34830.1 - 0.0019 17.5 0.2 0.0019 17.5 0.2 1.9 2 0 0 2 2 2 1 NB-ARC domain NACHT PF05729.12 EGR34830.1 - 0.0034 17.3 0.2 0.016 15.2 0.1 2.2 1 1 0 1 1 1 1 NACHT domain Cdc6_C PF09079.11 EGR34830.1 - 0.0044 17.0 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain DUF4355 PF14265.6 EGR34830.1 - 0.0075 16.5 1.5 0.93 9.7 0.6 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4355) RuvB_N PF05496.12 EGR34830.1 - 0.057 13.2 0.6 8 6.2 0.0 2.8 1 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 EGR34830.1 - 0.13 12.6 0.1 1.1 9.6 0.1 2.2 1 1 0 1 1 1 0 AAA domain Carbpep_Y_N PF05388.11 EGR34830.1 - 2 9.0 6.7 60 4.2 0.6 3.5 3 1 0 3 3 3 0 Carboxypeptidase Y pro-peptide DUF1581 PF07619.11 EGR34831.1 - 0.05 13.8 0.1 0.05 13.8 0.1 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1581) TTL PF03133.15 EGR34832.1 - 9.1e-47 159.6 26.6 3.6e-45 154.4 19.9 3.6 2 1 2 4 4 4 2 Tubulin-tyrosine ligase family H_PPase PF03030.16 EGR34833.1 - 2.1e-110 370.3 7.3 2.1e-110 370.3 7.3 1.4 1 1 1 2 2 2 1 Inorganic H+ pyrophosphatase HEAT PF02985.22 EGR34834.1 - 1.4e-28 96.5 3.5 0.0024 18.0 0.0 11.7 11 0 0 11 11 11 5 HEAT repeat HEAT_2 PF13646.6 EGR34834.1 - 6.3e-26 90.6 0.0 2.5e-07 31.0 0.0 6.2 4 2 2 6 6 6 4 HEAT repeats Vac14_Fab1_bd PF12755.7 EGR34834.1 - 9.3e-09 35.8 13.0 0.009 16.6 1.0 6.3 4 4 2 6 6 6 3 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGR34834.1 - 4e-07 30.2 20.9 0.0063 16.6 1.4 6.0 1 1 3 6 6 6 3 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGR34834.1 - 5.7e-06 26.1 13.2 0.002 17.8 0.7 4.8 2 1 4 6 6 6 2 CLASP N terminal NICE-3 PF07406.11 EGR34834.1 - 0.016 15.2 0.8 0.048 13.6 0.2 2.1 2 0 0 2 2 2 0 NICE-3 protein Phage_gp49_66 PF13876.6 EGR34834.1 - 0.025 14.9 0.1 0.24 11.8 0.0 2.3 2 0 0 2 2 2 0 Phage protein (N4 Gp49/phage Sf6 gene 66) family DUF1308 PF07000.11 EGR34834.1 - 0.087 12.8 0.2 2.9 7.8 0.0 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1308) Nse4-Nse3_bdg PF15412.6 EGR34834.1 - 0.096 12.8 0.0 0.29 11.3 0.0 1.8 1 0 0 1 1 1 0 Binding domain of Nse4/EID3 to Nse3-MAGE RPN6_N PF18055.1 EGR34834.1 - 0.18 12.2 5.0 0.25 11.7 0.4 3.2 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF5071 PF16804.5 EGR34834.1 - 0.53 10.6 5.5 3.7 7.8 0.2 3.9 2 1 2 4 4 4 0 Domain of unknown function (DUF5071) PAS_9 PF13426.7 EGR34835.1 - 0.0035 17.6 2.6 0.24 11.7 0.1 3.4 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 EGR34835.1 - 0.012 15.6 0.0 0.064 13.2 0.0 2.3 1 0 0 1 1 1 0 PAS fold Bystin PF05291.11 EGR34836.1 - 3e-92 309.0 3.1 3.6e-92 308.8 3.1 1.0 1 0 0 1 1 1 1 Bystin Kelch_5 PF13854.6 EGR34838.1 - 1.4e-34 117.5 4.2 4.1e-05 23.5 0.0 7.2 7 0 0 7 7 7 5 Kelch motif Kelch_4 PF13418.6 EGR34838.1 - 1.9e-34 117.4 1.0 3.4e-07 30.1 0.0 7.2 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EGR34838.1 - 3.8e-27 93.6 3.9 0.0001 22.5 0.1 7.4 5 1 2 7 7 7 6 Kelch motif Kelch_3 PF13415.6 EGR34838.1 - 5.7e-26 90.3 2.1 4.5e-05 23.6 0.0 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_2 PF07646.15 EGR34838.1 - 3.4e-21 74.3 0.8 0.0072 16.3 0.0 6.6 6 0 0 6 6 6 5 Kelch motif AMPK1_CBM PF16561.5 EGR34838.1 - 2.9e-19 69.1 9.5 4e-12 46.2 2.4 3.6 3 0 0 3 3 3 2 Glycogen recognition site of AMP-activated protein kinase Kelch_1 PF01344.25 EGR34838.1 - 1.5e-18 66.1 0.1 0.0092 15.5 0.0 6.8 7 0 0 7 7 7 4 Kelch motif Med3 PF11593.8 EGR34838.1 - 0.55 9.4 11.3 1.1 8.4 11.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Endopep_inhib PF16800.5 EGR34839.1 - 0.023 14.6 1.1 0.034 14.1 1.1 1.2 1 0 0 1 1 1 0 IseA DL-endopeptidase inhibitor RE_ApaLI PF09499.10 EGR34839.1 - 0.053 13.2 0.2 0.078 12.7 0.2 1.2 1 0 0 1 1 1 0 ApaLI-like restriction endonuclease Microtub_bd PF16796.5 EGR34839.1 - 0.078 12.9 2.2 1.1 9.2 0.3 2.2 1 1 1 2 2 2 0 Microtubule binding LCIB_C_CA PF18599.1 EGR34839.1 - 0.12 11.7 0.1 0.33 10.2 0.0 1.6 2 0 0 2 2 2 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases UMPH-1 PF05822.12 EGR34840.1 - 6.8e-38 130.6 10.2 9.2e-38 130.2 10.2 1.2 1 0 0 1 1 1 1 Pyrimidine 5'-nucleotidase (UMPH-1) HAD PF12710.7 EGR34840.1 - 2.7e-05 24.6 0.0 6.3e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase ArsP_1 PF03773.13 EGR34840.1 - 0.096 11.8 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 Predicted permease EutA PF06277.11 EGR34840.1 - 0.16 10.8 0.4 0.35 9.6 0.3 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation protein EutA Y_phosphatase PF00102.27 EGR34841.1 - 5.7e-41 140.6 11.7 4.6e-35 121.3 4.9 3.7 3 1 0 3 3 3 2 Protein-tyrosine phosphatase ALMT PF11744.8 EGR34841.1 - 0.01 14.7 9.9 0.015 14.1 9.9 1.4 1 0 0 1 1 1 1 Aluminium activated malate transporter CLN3 PF02487.17 EGR34841.1 - 4.2 6.3 8.8 7 5.6 8.8 1.3 1 0 0 1 1 1 0 CLN3 protein Ribosomal_S17_N PF16205.5 EGR34842.1 - 2.3e-32 111.2 0.4 3.9e-32 110.4 0.4 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EGR34842.1 - 1.9e-24 85.6 0.5 2.8e-24 85.0 0.5 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Ion_trans PF00520.31 EGR34843.1 - 5.5e-23 81.5 84.4 6.9e-15 54.9 41.3 2.9 3 0 0 3 3 3 2 Ion transport protein Kinesin PF00225.23 EGR34845.1 - 6.6e-98 327.7 4.8 6.6e-98 327.7 4.8 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGR34845.1 - 3.2e-19 69.4 0.6 3.2e-19 69.4 0.6 2.8 2 1 1 3 3 3 1 Microtubule binding AAA_16 PF13191.6 EGR34845.1 - 0.06 13.7 0.1 0.19 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 EGR34845.1 - 0.21 11.6 0.1 0.21 11.6 0.1 3.3 3 0 0 3 3 3 0 Helicase HerA, central domain DDHD PF02862.17 EGR34845.1 - 5 7.2 9.9 0.79 9.8 5.9 1.6 2 0 0 2 2 2 0 DDHD domain EF-hand_1 PF00036.32 EGR34846.1 - 1.9e-29 98.9 13.8 1.4e-07 30.5 1.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGR34846.1 - 4.4e-27 94.3 9.3 1.6e-13 50.9 3.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGR34846.1 - 7e-23 78.6 10.7 3.4e-07 29.7 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 EGR34846.1 - 2.8e-22 78.3 14.5 1.3e-11 44.1 0.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EGR34846.1 - 8.8e-15 53.4 13.9 0.00014 21.2 0.5 4.4 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EGR34846.1 - 5.8e-13 49.0 0.7 1.2e-07 31.9 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EGR34846.1 - 1.3e-05 25.4 1.7 0.12 12.7 0.1 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGR34846.1 - 1.6e-05 24.8 7.1 0.0044 16.9 1.0 3.2 1 1 2 3 3 3 1 Cytoskeletal-regulatory complex EF hand DUF3008 PF11450.8 EGR34846.1 - 0.0005 20.2 0.3 0.0013 18.9 0.3 1.6 1 0 0 1 1 1 1 Protein of unknwon function (DUF3008) Caleosin PF05042.13 EGR34846.1 - 0.0015 18.5 1.4 1.6 8.6 0.0 3.6 1 1 3 4 4 4 1 Caleosin related protein EF-hand_14 PF17959.1 EGR34846.1 - 0.0031 17.8 3.5 0.17 12.2 0.7 2.4 2 0 0 2 2 2 1 EF-hand domain Toprim_2 PF13155.6 EGR34846.1 - 0.021 15.3 2.3 0.4 11.1 2.1 2.4 1 1 1 2 2 2 0 Toprim-like Acetyltransf_11 PF13720.6 EGR34846.1 - 0.04 14.4 0.2 9.5 6.8 0.0 2.4 1 1 1 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 Seryl_tRNA_N PF02403.22 EGR34846.1 - 0.048 13.9 1.4 0.12 12.6 1.4 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Ribonuc_red_lgN PF00317.21 EGR34846.1 - 0.058 13.4 1.3 0.33 11.0 0.1 2.3 2 1 0 2 2 2 0 Ribonucleotide reductase, all-alpha domain DUF3349 PF11829.8 EGR34846.1 - 0.078 13.8 0.9 18 6.2 0.0 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3349) DUF4476 PF14771.6 EGR34846.1 - 0.11 12.8 3.0 0.59 10.5 0.3 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4476) 4HBT PF03061.22 EGR34847.1 - 1.9e-09 37.7 0.0 2.4e-05 24.6 0.0 2.2 2 0 0 2 2 2 2 Thioesterase superfamily 4HBT_2 PF13279.6 EGR34847.1 - 0.0043 17.5 1.4 0.84 10.1 0.0 2.2 1 1 0 2 2 2 2 Thioesterase-like superfamily YiiD_C PF09500.10 EGR34847.1 - 0.014 15.2 0.0 0.085 12.7 0.0 2.2 2 1 1 3 3 3 0 Putative thioesterase (yiiD_Cterm) MaoC_dehydratas PF01575.19 EGR34847.1 - 0.076 12.6 0.0 0.71 9.5 0.0 2.1 2 0 0 2 2 2 0 MaoC like domain zf_C2H2_10 PF18414.1 EGR34847.1 - 0.13 11.9 2.1 0.16 11.5 0.5 1.9 2 0 0 2 2 2 0 C2H2 type zinc-finger NIF PF03031.18 EGR34848.1 - 2.4e-45 154.1 4.7 2.7e-45 153.9 4.0 1.5 1 1 0 1 1 1 1 NLI interacting factor-like phosphatase Actin PF00022.19 EGR34849.1 - 5.1e-103 344.8 0.0 5.8e-103 344.6 0.0 1.0 1 0 0 1 1 1 1 Actin DUF2969 PF11184.8 EGR34849.1 - 0.012 16.0 0.0 0.038 14.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2969) zf-UBR PF02207.20 EGR34850.1 - 1e-14 54.4 16.6 1e-14 54.4 16.6 4.5 4 0 0 4 4 4 1 Putative zinc finger in N-recognin (UBR box) Ion_trans PF00520.31 EGR34851.1 - 1.5e-46 158.6 66.6 1.7e-29 102.8 32.0 3.0 2 1 0 2 2 2 2 Ion transport protein EF-hand_6 PF13405.6 EGR34851.1 - 0.043 13.7 2.3 12 6.1 0.1 4.2 3 0 0 3 3 3 0 EF-hand domain Lactamase_B_6 PF16661.5 EGR34852.1 - 4e-40 137.3 2.8 5.5e-40 136.9 2.8 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain PAP_central PF04928.17 EGR34852.1 - 0.023 13.7 0.2 0.029 13.3 0.2 1.1 1 0 0 1 1 1 0 Poly(A) polymerase central domain DUF2252 PF10009.9 EGR34853.1 - 0.19 10.7 1.2 0.35 9.9 1.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2252) WD40 PF00400.32 EGR34854.1 - 0.0044 17.8 0.6 51 5.0 0.0 4.2 4 0 0 4 4 4 2 WD domain, G-beta repeat CitMHS PF03600.16 EGR34855.1 - 0.15 11.3 0.0 2.2 7.4 0.0 2.7 1 1 0 1 1 1 0 Citrate transporter Fumble PF03630.14 EGR34856.1 - 2e-38 132.4 5.2 2.5e-38 132.1 5.2 1.2 1 1 0 1 1 1 1 Fumble Merozoite_SPAM PF07133.11 EGR34856.1 - 0.18 11.8 1.9 1.1 9.3 0.9 2.1 2 0 0 2 2 2 0 Merozoite surface protein (SPAM) ABA_GPCR PF12430.8 EGR34858.1 - 6.7e-23 81.4 14.6 6.7e-23 81.4 14.6 2.7 2 1 1 3 3 3 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 EGR34858.1 - 2.2e-07 30.9 0.0 6.2e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal DUF281 PF03436.13 EGR34860.1 - 0.077 13.4 4.1 0.1 13.0 1.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF281) MSG PF02349.15 EGR34860.1 - 5 7.4 27.9 0.94 9.7 7.2 2.6 1 1 1 2 2 2 0 Major surface glycoprotein Paramecium_SA PF01508.16 EGR34860.1 - 5.7 7.4 22.5 1.8e+04 -3.8 22.5 3.2 1 1 0 1 1 1 0 Paramecium surface antigen domain cNMP_binding PF00027.29 EGR34863.1 - 5.5e-23 80.8 0.0 6.2e-07 29.4 0.0 3.2 3 0 0 3 3 3 3 Cyclic nucleotide-binding domain Pkinase PF00069.25 EGR34865.1 - 1.1e-66 225.0 1.3 1.3e-66 224.7 1.3 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34865.1 - 5e-36 124.3 0.0 6.7e-36 123.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGR34865.1 - 0.00021 20.7 0.0 0.00042 19.7 0.0 1.4 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 EGR34865.1 - 0.0023 17.5 0.5 0.0037 16.8 0.5 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.14 EGR34865.1 - 0.0031 16.9 0.0 0.0059 16.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Cyt-b5 PF00173.28 EGR34866.1 - 2.9e-08 33.7 0.0 6.2e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain cNMP_binding PF00027.29 EGR34867.1 - 5.6e-12 45.6 0.0 1.1e-11 44.7 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Pkinase PF00069.25 EGR34868.1 - 3.4e-67 226.6 0.1 3.4e-67 226.6 0.1 2.8 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34868.1 - 2.3e-49 168.0 0.0 4.9e-49 167.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR34868.1 - 1.4e-07 30.7 3.0 1.6e-06 27.2 0.0 2.8 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 EGR34868.1 - 2.6e-07 30.2 0.3 3.1e-06 26.7 0.0 2.5 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGR34868.1 - 0.00056 19.3 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5636 PF18686.1 EGR34868.1 - 0.12 12.6 15.7 0.4 10.8 4.7 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5636) APH PF01636.23 EGR34868.1 - 0.21 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Acylphosphatase PF00708.18 EGR34869.1 - 5.9e-12 45.8 0.4 1e-11 45.1 0.1 1.5 2 0 0 2 2 2 1 Acylphosphatase SurA_N_2 PF13623.6 EGR34869.1 - 0.013 15.3 0.2 0.017 15.0 0.2 1.2 1 0 0 1 1 1 0 SurA N-terminal domain SBDS PF01172.18 EGR34870.1 - 1.4e-26 92.4 3.0 1.4e-26 92.4 3.0 2.4 2 0 0 2 2 2 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SBDS_C PF09377.10 EGR34870.1 - 4.9e-16 58.8 27.2 1.3e-15 57.5 23.0 3.3 2 1 0 2 2 2 1 SBDS protein C-terminal domain zf-C2H2_jaz PF12171.8 EGR34870.1 - 1.5 9.2 9.1 0.19 12.0 3.3 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding PX PF00787.24 EGR34872.1 - 9.3e-19 67.5 0.1 9.3e-19 67.5 0.1 2.1 2 0 0 2 2 2 1 PX domain Presenilin PF01080.17 EGR34872.1 - 0.35 9.6 3.9 0.51 9.1 3.9 1.3 1 0 0 1 1 1 0 Presenilin HCO3_cotransp PF00955.21 EGR34872.1 - 0.6 8.9 9.3 1.2 7.9 9.3 1.5 1 0 0 1 1 1 0 HCO3- transporter family DUF3405 PF11885.8 EGR34872.1 - 2 6.9 13.6 3.1 6.3 13.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) Secretin_N_2 PF07655.13 EGR34872.1 - 4 8.0 16.1 0.54 10.8 11.7 1.8 2 0 0 2 2 2 0 Secretin N-terminal domain Cation_efflux PF01545.21 EGR34873.1 - 1.1e-44 152.6 21.4 1.6e-44 152.0 21.4 1.3 1 1 0 1 1 1 1 Cation efflux family Macoilin PF09726.9 EGR34873.1 - 0.0007 18.3 16.4 0.0007 18.3 16.4 1.4 2 0 0 2 2 2 1 Macoilin family BPD_transp_2 PF02653.16 EGR34873.1 - 0.044 12.9 0.0 0.044 12.9 0.0 2.1 2 0 0 2 2 2 0 Branched-chain amino acid transport system / permease component LAP1C PF05609.12 EGR34873.1 - 0.28 10.2 21.9 0.076 12.1 17.8 1.8 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Hid1 PF12722.7 EGR34873.1 - 3 5.9 12.5 5.2 5.1 12.5 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.22 EGR34873.1 - 5.9 6.0 49.9 5.1e+02 -0.4 49.3 2.7 1 1 0 1 1 1 0 ZIP Zinc transporter DUF3671 PF12420.8 EGR34873.1 - 6.8 6.8 7.7 1.1 9.3 0.9 2.8 2 1 0 2 2 2 0 Protein of unknown function PIP5K PF01504.18 EGR34874.1 - 1.4e-72 244.2 21.9 1.4e-72 244.2 21.9 3.8 2 2 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase RSN1_TM PF13967.6 EGR34874.1 - 0.012 15.3 0.0 0.42 10.4 0.0 2.8 2 0 0 2 2 2 0 Late exocytosis, associated with Golgi transport Pkinase PF00069.25 EGR34875.1 - 1.5e-65 221.2 0.0 1.5e-65 221.2 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34875.1 - 9.6e-34 116.8 2.7 1.7e-25 89.8 0.1 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EGR34875.1 - 0.00017 20.7 2.9 0.00017 20.7 2.9 2.0 2 1 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EGR34875.1 - 0.007 16.3 0.7 0.13 12.2 0.4 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family HSP70 PF00012.20 EGR34876.1 - 3.9e-107 358.9 8.5 5.1e-105 351.9 2.8 2.8 2 1 1 3 3 3 2 Hsp70 protein MreB_Mbl PF06723.13 EGR34876.1 - 5.1e-09 35.4 0.1 3.6e-08 32.6 0.0 2.2 2 1 0 2 2 2 1 MreB/Mbl protein DUF4733 PF15878.5 EGR34876.1 - 0.095 13.2 0.2 3.2 8.3 0.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4733) CCDC53 PF10152.9 EGR34876.1 - 6.7 7.1 20.2 1.6 9.1 12.0 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex CHORD PF04968.12 EGR34877.1 - 2.7e-46 156.1 32.2 1.2e-23 83.6 9.8 2.6 2 0 0 2 2 2 2 CHORD BTK PF00779.19 EGR34877.1 - 0.0021 17.8 5.8 0.3 11.0 0.6 3.1 2 0 0 2 2 2 2 BTK motif PH_12 PF16457.5 EGR34877.1 - 0.57 10.7 9.0 0.85 10.2 9.0 1.3 1 0 0 1 1 1 0 Pleckstrin homology domain ALMT PF11744.8 EGR34877.1 - 1.1 8.1 8.6 1.2 7.9 8.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Neur_chan_memb PF02932.16 EGR34877.1 - 1.6 8.7 6.7 1.8 8.6 6.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Roughex PF06020.11 EGR34877.1 - 5.3 6.0 9.4 6.4 5.8 9.4 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Presenilin PF01080.17 EGR34877.1 - 5.8 5.6 11.6 7 5.3 11.6 1.1 1 0 0 1 1 1 0 Presenilin HCO3_cotransp PF00955.21 EGR34877.1 - 5.9 5.6 5.1 6.2 5.5 5.1 1.2 1 0 0 1 1 1 0 HCO3- transporter family Sec7 PF01369.20 EGR34878.1 - 5e-43 146.9 8.9 5e-43 146.9 8.9 3.0 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 EGR34878.1 - 3.7e-34 117.9 9.9 3.7e-34 117.9 9.9 4.0 4 1 0 4 4 4 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EGR34878.1 - 3.6e-24 84.4 1.1 3.6e-24 84.4 1.1 5.6 6 1 1 7 7 7 2 Domain of unknown function (DUF1981) DUF4667 PF15700.5 EGR34878.1 - 0.1 12.7 2.9 0.074 13.1 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) zf-HIT PF04438.16 EGR34878.1 - 1.2 9.1 4.9 2.4 8.1 4.9 1.5 1 0 0 1 1 1 0 HIT zinc finger BCAS2 PF05700.11 EGR34879.1 - 1.5e-29 103.2 9.1 2.3e-29 102.6 9.1 1.2 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) Myb_Cef PF11831.8 EGR34879.1 - 0.011 15.3 1.2 0.011 15.3 1.2 1.9 1 1 0 2 2 2 0 pre-mRNA splicing factor component bZIP_2 PF07716.15 EGR34879.1 - 0.65 10.1 13.6 6.7 6.9 6.9 3.1 1 1 3 4 4 4 0 Basic region leucine zipper K-box PF01486.17 EGR34879.1 - 2.7 8.2 19.3 5.8 7.2 0.2 4.1 2 1 2 4 4 4 0 K-box region bZIP_1 PF00170.21 EGR34879.1 - 8 6.6 14.6 15 5.8 5.3 3.1 2 1 1 3 3 3 0 bZIP transcription factor RNA_lig_T4_1 PF09511.10 EGR34881.1 - 2.2e-05 24.4 0.2 2.7e-05 24.1 0.2 1.2 1 0 0 1 1 1 1 RNA ligase Pkinase PF00069.25 EGR34884.1 - 1.4e-58 198.4 2.2 1.4e-58 198.4 2.2 3.2 3 2 1 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34884.1 - 8e-38 130.2 0.6 8e-38 130.2 0.6 2.0 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR34884.1 - 2.4e-05 23.3 0.0 2.4e-05 23.3 0.0 2.9 3 0 0 3 3 3 1 Fungal protein kinase ABC1 PF03109.16 EGR34884.1 - 0.03 14.5 0.4 0.56 10.4 0.0 2.9 2 0 0 2 2 2 0 ABC1 family APH PF01636.23 EGR34884.1 - 0.044 13.7 0.0 0.3 11.0 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family Sugar_tr PF00083.24 EGR34886.1 - 1.2e-71 241.9 29.9 1.5e-71 241.6 29.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGR34886.1 - 4.7e-25 88.3 15.2 4.7e-25 88.3 15.2 2.0 1 1 1 2 2 2 1 Major Facilitator Superfamily FA_desaturase PF00487.24 EGR34886.1 - 1.7 8.4 7.3 0.33 10.8 1.1 2.5 3 0 0 3 3 3 0 Fatty acid desaturase Phospholip_A2_2 PF05826.12 EGR34887.1 - 1.8 8.8 5.7 1.2 9.4 2.4 2.4 2 0 0 2 2 2 0 Phospholipase A2 ParA PF10609.9 EGR34889.1 - 8.4e-98 326.7 0.0 1.2e-97 326.2 0.0 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Peptidase_C1 PF00112.23 EGR34889.1 - 1.1e-48 166.2 8.6 2.1e-48 165.3 8.6 1.5 1 0 0 1 1 1 1 Papain family cysteine protease CathepsinC_exc PF08773.11 EGR34889.1 - 1.2e-33 116.0 0.5 2.7e-33 114.8 0.5 1.7 1 0 0 1 1 1 1 Cathepsin C exclusion domain CbiA PF01656.23 EGR34889.1 - 4.7e-10 39.6 0.0 1.9e-09 37.7 0.0 2.0 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.15 EGR34889.1 - 8.5e-08 31.7 0.0 3.3e-07 29.8 0.0 2.0 2 0 0 2 2 2 1 Anion-transporting ATPase AAA_31 PF13614.6 EGR34889.1 - 4.1e-07 30.1 0.4 6.4e-06 26.2 0.4 2.4 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 EGR34889.1 - 1.5e-05 24.4 0.0 6.1e-05 22.4 0.0 1.9 1 1 0 1 1 1 1 ATPase MipZ Peptidase_C1_2 PF03051.15 EGR34889.1 - 0.0011 17.9 0.9 0.0011 17.9 0.9 1.7 2 0 0 2 2 2 1 Peptidase C1-like family Fer4_NifH PF00142.18 EGR34889.1 - 0.0018 17.8 0.1 0.22 10.9 0.0 2.6 2 1 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MeaB PF03308.16 EGR34889.1 - 0.0023 17.0 0.0 0.004 16.2 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 EGR34889.1 - 0.0028 17.3 0.0 0.0047 16.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain CBP_BcsQ PF06564.12 EGR34889.1 - 0.0062 16.0 0.0 0.013 15.0 0.0 1.5 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ RsgA_GTPase PF03193.16 EGR34889.1 - 0.0091 15.9 0.1 0.02 14.8 0.1 1.5 1 0 0 1 1 1 1 RsgA GTPase CLP1_P PF16575.5 EGR34889.1 - 0.018 14.8 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop APS_kinase PF01583.20 EGR34889.1 - 0.042 13.7 0.0 0.08 12.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase NB-ARC PF00931.22 EGR34889.1 - 0.081 12.1 0.1 0.17 11.0 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_26 PF13500.6 EGR34889.1 - 0.11 12.3 0.1 4.5 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGR34889.1 - 0.16 12.3 0.2 0.99 9.7 0.1 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGR34889.1 - 0.18 12.4 0.1 0.61 10.6 0.1 1.9 2 0 0 2 2 1 0 AAA domain CTP_transf_1 PF01148.20 EGR34890.1 - 0.56 9.9 6.5 0.63 9.8 6.5 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family adh_short_C2 PF13561.6 EGR34891.1 - 3.3e-30 105.4 0.1 2.3e-26 92.8 0.0 2.3 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGR34891.1 - 5.4e-26 91.3 1.1 4.8e-25 88.2 1.1 1.9 1 1 0 1 1 1 1 short chain dehydrogenase DUF1295 PF06966.12 EGR34892.1 - 2.9e-07 30.3 1.3 5e-07 29.5 1.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) PEMT PF04191.13 EGR34892.1 - 1e-05 25.9 0.8 1e-05 25.9 0.8 2.1 2 1 0 2 2 2 1 Phospholipid methyltransferase Steroid_dh PF02544.16 EGR34892.1 - 1.1e-05 25.5 5.5 2.4e-05 24.4 5.5 1.7 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase ICMT PF04140.14 EGR34892.1 - 0.018 15.5 0.1 0.05 14.0 0.1 1.8 1 0 0 1 1 1 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Pkinase PF00069.25 EGR34893.1 - 4.7e-62 209.7 0.0 4.7e-62 209.7 0.0 2.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGR34893.1 - 2.4e-30 105.7 0.0 4.3e-30 104.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGR34893.1 - 0.0011 17.8 0.0 0.0071 15.2 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Shisa PF13908.6 EGR34893.1 - 0.013 15.7 2.1 0.023 14.9 2.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Orf78 PF06024.12 EGR34893.1 - 0.024 14.9 7.4 0.062 13.6 7.4 1.6 1 0 0 1 1 1 0 Orf78 (ac78) DUF2207 PF09972.9 EGR34893.1 - 0.032 13.0 7.4 0.026 13.3 5.8 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) TMEM154 PF15102.6 EGR34893.1 - 0.052 13.4 9.1 0.091 12.7 9.1 1.3 1 0 0 1 1 1 0 TMEM154 protein family DUF5383 PF17355.2 EGR34893.1 - 0.46 10.9 12.9 0.039 14.3 5.4 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5383) FtsH_ext PF06480.15 EGR34893.1 - 5.6 7.4 7.3 15 5.9 7.3 1.7 1 0 0 1 1 1 0 FtsH Extracellular NifU PF01106.17 EGR34894.1 - 3.2e-26 91.3 0.1 4.4e-26 90.8 0.1 1.2 1 0 0 1 1 1 1 NifU-like domain Nfu_N PF08712.11 EGR34894.1 - 1.1e-18 67.0 0.1 2.8e-18 65.8 0.0 1.7 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal DUF447 PF04289.12 EGR34895.1 - 0.13 12.1 0.0 0.13 12.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF447) Bud13 PF09736.9 EGR34897.1 - 6.6e-36 123.9 5.4 6.6e-36 123.9 5.4 2.1 2 0 0 2 2 2 1 Pre-mRNA-splicing factor of RES complex DDE_Tnp_IS240 PF13610.6 EGR34897.1 - 0.46 10.7 9.6 0.065 13.5 4.8 2.0 1 1 1 2 2 2 0 DDE domain UPF0560 PF10577.9 EGR34897.1 - 2.5 6.5 15.8 2.8 6.3 15.2 1.3 1 1 0 1 1 1 0 Uncharacterised protein family UPF0560 Carb_anhydrase PF00194.21 EGR34898.1 - 7.1e-36 124.0 9.2 8e-28 97.6 4.4 3.3 3 1 0 3 3 3 2 Eukaryotic-type carbonic anhydrase Macoilin PF09726.9 EGR34898.1 - 0.0068 15.0 19.3 0.008 14.8 19.3 1.2 1 0 0 1 1 1 1 Macoilin family Dapper PF15268.6 EGR34898.1 - 0.2 10.5 19.8 0.24 10.2 19.8 1.1 1 0 0 1 1 1 0 Dapper SMYLE_N PF18615.1 EGR34898.1 - 0.93 9.0 11.7 1.7 8.1 11.7 1.6 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain Yip1 PF04893.17 EGR34899.1 - 1e-08 35.1 16.0 2.2e-08 34.0 15.8 1.5 1 1 0 1 1 1 1 Yip1 domain SPC25 PF06703.11 EGR34899.1 - 5.2 6.8 13.1 2.5e+02 1.4 13.0 2.3 1 1 0 1 1 1 0 Microsomal signal peptidase 25 kDa subunit (SPC25) ASH PF15780.5 EGR34900.1 - 5.2e-30 103.6 26.3 0.00012 22.2 0.1 12.5 12 0 0 12 12 12 7 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 EGR34900.1 - 6e-10 38.9 42.5 0.0028 17.5 0.1 11.2 12 0 0 12 12 12 4 MSP (Major sperm protein) domain DUF1573 PF07610.11 EGR34900.1 - 8.8e-07 28.9 31.7 0.72 9.9 1.0 11.0 13 0 0 13 13 13 4 Protein of unknown function (DUF1573) TMEM131_like PF12371.8 EGR34900.1 - 1.3e-06 28.5 0.5 1.8e-05 24.9 0.0 10.8 14 0 0 14 14 14 3 Transmembrane protein 131-like CH PF00307.31 EGR34900.1 - 0.0064 16.7 2.1 0.012 15.8 0.1 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain CH_2 PF06294.11 EGR34900.1 - 0.0097 16.0 0.4 0.097 12.8 0.1 3.1 2 0 0 2 2 2 1 CH-like domain in sperm protein DUF4586 PF15239.6 EGR34901.1 - 7.5e-53 180.7 19.9 9.1e-53 180.4 19.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) EF-hand_7 PF13499.6 EGR34902.1 - 4.4e-19 68.7 3.7 1.7e-12 47.6 0.7 2.9 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGR34902.1 - 2.1e-14 51.9 9.8 0.00012 21.4 0.3 4.7 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGR34902.1 - 3.5e-13 48.3 6.1 0.00016 21.3 0.4 4.9 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EGR34902.1 - 4.4e-08 32.3 1.2 0.0059 16.0 0.0 3.4 2 0 0 2 2 2 2 EF hand SPARC_Ca_bdg PF10591.9 EGR34902.1 - 9e-05 22.8 2.4 0.0067 16.7 0.7 2.8 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EGR34902.1 - 0.037 14.4 0.7 5.2 7.5 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain EF-hand_10 PF14788.6 EGR34902.1 - 0.066 13.1 1.8 1.2 9.0 0.0 3.5 4 0 0 4 4 4 0 EF hand DUF5613 PF18467.1 EGR34902.1 - 0.66 10.4 7.9 0.56 10.7 3.0 3.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5613) EF-hand_8 PF13833.6 EGR34902.1 - 3.5 7.5 11.0 12 5.8 0.1 4.9 5 1 1 6 6 6 0 EF-hand domain pair DUF1126 PF06565.12 EGR34903.1 - 3.7e-90 296.7 11.6 1.9e-36 124.0 0.3 4.1 4 0 0 4 4 4 3 DUF1126 PH-like domain EF-hand_6 PF13405.6 EGR34903.1 - 0.17 11.9 1.0 0.93 9.6 0.2 2.7 2 0 0 2 2 2 0 EF-hand domain Limkain-b1 PF11608.8 EGR34904.1 - 0.15 12.2 0.0 15 5.7 0.0 2.6 2 0 0 2 2 2 0 Limkain b1 Radial_spoke PF04712.12 EGR34905.1 - 1.2e-79 268.6 20.4 2.2e-60 205.0 7.7 2.1 1 1 1 2 2 2 2 Radial spokehead-like protein EF-hand_1 PF00036.32 EGR34906.1 - 1.1e-13 49.6 10.5 1.9e-05 23.8 0.2 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGR34906.1 - 3.8e-11 42.0 8.7 2.7e-05 23.7 0.5 3.9 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 EGR34906.1 - 4.8e-11 42.9 8.5 4.5e-06 27.0 1.5 2.7 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 EGR34906.1 - 2.7e-08 33.5 6.2 0.0041 16.9 0.7 3.5 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGR34906.1 - 1.3e-05 24.5 8.4 0.0042 16.5 0.4 3.3 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 EGR34906.1 - 0.0012 19.1 0.1 0.31 11.4 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain SPARC_Ca_bdg PF10591.9 EGR34906.1 - 0.0013 19.0 2.8 0.079 13.3 0.2 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Sec6 PF06046.13 EGR34906.1 - 0.004 15.6 0.8 0.0052 15.2 0.8 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec6 Tex_N PF09371.10 EGR34906.1 - 0.035 13.8 2.1 0.13 11.9 2.1 2.2 1 1 0 1 1 1 0 Tex-like protein N-terminal domain DUF2551 PF10826.8 EGR34906.1 - 0.061 13.6 0.0 0.14 12.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2551) EF-hand_4 PF12763.7 EGR34906.1 - 0.26 11.3 3.5 0.44 10.5 1.4 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 EGR34906.1 - 9.5 6.2 8.9 1.2 9.1 0.8 3.2 3 1 1 4 4 4 0 EF hand hGDE_N PF14699.6 EGR34907.1 - 0.025 14.7 0.9 0.068 13.3 0.9 1.7 1 0 0 1 1 1 0 N-terminal domain from the human glycogen debranching enzyme DUF2951 PF11166.8 EGR34907.1 - 0.12 12.6 6.6 0.047 13.9 2.3 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF2951) DUF4413 PF14372.6 EGR34908.1 - 0.031 14.6 0.0 0.05 14.0 0.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4413) Fringe PF02434.16 EGR34908.1 - 0.074 12.5 0.0 0.096 12.1 0.0 1.2 1 0 0 1 1 1 0 Fringe-like Phtf-FEM1B_bdg PF12129.8 EGR34908.1 - 1.2 8.9 7.4 2.1 8.1 7.4 1.4 1 0 0 1 1 1 0 Male germ-cell putative homeodomain transcription factor Thioredoxin_16 PF18569.1 EGR34909.1 - 0.48 10.6 4.3 1.5 9.0 4.3 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain MFS_1 PF07690.16 EGR34910.1 - 1.1e-10 41.0 31.7 5.5e-10 38.7 32.3 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily STI1 PF17830.1 EGR34911.1 - 1.4 8.9 5.6 14 5.7 0.3 2.6 2 0 0 2 2 2 0 STI1 domain C2 PF00168.30 EGR34914.1 - 0.072 13.4 2.7 0.15 12.4 0.2 2.9 3 1 0 3 3 3 0 C2 domain betaPIX_CC PF16523.5 EGR34915.1 - 0.011 15.5 1.4 0.011 15.5 1.4 3.0 2 1 1 3 3 3 0 betaPIX coiled coil SAB PF04382.13 EGR34915.1 - 0.028 14.5 0.3 0.1 12.7 0.3 2.0 1 0 0 1 1 1 0 SAB domain Lig_chan-Glu_bd PF10613.9 EGR34915.1 - 1.1 9.5 8.9 0.1 12.8 1.1 2.9 2 1 0 3 3 3 0 Ligated ion channel L-glutamate- and glycine-binding site Fez1 PF06818.15 EGR34915.1 - 2.3 8.6 26.9 3.6 8.0 5.0 2.9 1 1 0 2 2 2 0 Fez1 FRG1 PF06229.12 EGR34915.1 - 3.8 7.2 15.1 1.9 8.2 7.7 2.3 1 1 0 2 2 2 0 FRG1-like domain UPF0242 PF06785.11 EGR34915.1 - 9.4 6.3 31.8 1.2 9.2 4.3 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus WD40 PF00400.32 EGR34916.1 - 4.3e-10 40.0 2.2 0.17 12.8 0.0 4.8 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGR34916.1 - 3.6e-09 36.8 0.1 0.018 15.4 0.0 4.0 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Ciliates/Ichthyophthirius_multifiliis-JCVI-IMG1-V.1/GCA_000220395.1_JCVI-IMG1-V.1_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Ciliates/Ichthyophthirius_multifiliis-JCVI-IMG1-V.1/GCA_000220395.1_JCVI-IMG1-V.1_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Ciliates/Ichthyophthirius_multifiliis-JCVI-IMG1-V.1/GCA_000220395.1_JCVI-IMG1-V.1_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Ciliates/Ichthyophthirius_multifiliis-JCVI-IMG1-V.1/GCA_000220395.1_JCVI-IMG1-V.1_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 07:07:04 2019 # [ok]