# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- RVT_2 PF07727.14 PSC67003.1 - 6.1e-74 248.7 0.0 8.2e-74 248.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PSC67003.1 - 4.8e-24 84.8 0.0 1.9e-23 82.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 PSC67003.1 - 1.4e-09 37.7 0.0 3.4e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 PSC67003.1 - 7.2e-05 22.5 0.1 0.00024 20.8 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Phage_GPD PF05954.11 PSC67003.1 - 0.11 11.8 0.4 0.31 10.3 0.2 1.8 2 0 0 2 2 2 0 Phage late control gene D protein (GPD) Crr6 PF08847.11 PSC67003.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Chlororespiratory reduction 6 eIF-3_zeta PF05091.12 PSC67004.1 - 1.4e-91 308.1 0.0 2.7e-35 122.4 0.0 4.4 1 1 3 4 4 4 4 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1929 PF09118.11 PSC67005.1 - 8.3e-14 51.7 0.0 1e-13 51.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Sec63 PF02889.16 PSC67006.1 - 1.9e-12 46.9 0.0 4.8e-07 29.2 0.0 2.6 2 1 0 2 2 2 2 Sec63 Brl domain UPF0220 PF05255.11 PSC67007.1 - 9.5e-15 54.5 1.5 2.2e-14 53.4 1.1 1.5 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0220) DUF3611 PF12263.8 PSC67007.1 - 0.016 15.1 0.8 0.016 15.1 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) VirB8 PF04335.13 PSC67007.1 - 0.74 9.6 1.9 1 9.1 0.0 1.8 2 0 0 2 2 2 0 VirB8 protein CRAL_TRIO PF00650.20 PSC67008.1 - 0.0008 19.2 0.2 0.052 13.3 0.0 2.2 1 1 1 2 2 2 2 CRAL/TRIO domain Kinesin PF00225.23 PSC67009.1 - 1.2e-07 31.0 0.0 2.4e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain zf-4CXXC_R1 PF10497.9 PSC67009.1 - 0.83 9.9 10.0 2.2 8.5 10.0 1.7 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 zf-RING_2 PF13639.6 PSC67009.1 - 1.2 9.5 9.1 3.4 8.1 9.1 1.9 1 0 0 1 1 1 0 Ring finger domain RVT_2 PF07727.14 PSC67010.1 - 3.4e-71 239.7 0.0 4.7e-71 239.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PSC67010.1 - 0.00078 19.6 0.0 0.0036 17.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Crr6 PF08847.11 PSC67010.1 - 0.11 12.2 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Chlororespiratory reduction 6 DUF1598 PF07643.11 PSC67011.1 - 3.2 8.0 5.8 4.7 7.5 1.3 3.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1598) Alpha-amylase PF00128.24 PSC67013.1 - 4.1e-08 33.2 0.1 9.1e-07 28.7 0.1 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Glycos_transf_1 PF00534.20 PSC67013.1 - 7.3e-08 32.1 0.0 1.5e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 RRM_1 PF00076.22 PSC67014.1 - 1.1e-08 34.8 0.0 1.5e-08 34.4 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ig_5 PF16681.5 PSC67014.1 - 0.0029 18.0 0.1 0.0039 17.6 0.1 1.2 1 0 0 1 1 1 1 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain PPR_long PF17177.4 PSC67015.1 - 1.7e-10 40.7 1.7 1.7e-05 24.3 0.0 3.8 3 1 0 3 3 3 3 Pentacotripeptide-repeat region of PRORP SAP PF02037.27 PSC67015.1 - 1.1e-06 28.2 1.7 3.3e-06 26.7 0.4 2.4 2 0 0 2 2 2 1 SAP domain PPR_2 PF13041.6 PSC67015.1 - 0.00095 19.3 0.0 0.04 14.1 0.0 3.1 2 1 1 3 3 3 1 PPR repeat family PPR_3 PF13812.6 PSC67015.1 - 0.011 15.8 0.0 0.03 14.4 0.0 1.8 1 0 0 1 1 1 0 Pentatricopeptide repeat domain Cwf_Cwc_15 PF04889.12 PSC67015.1 - 0.047 13.4 2.5 0.082 12.6 2.5 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PPR PF01535.20 PSC67015.1 - 0.11 12.8 0.0 7.4 7.1 0.0 3.3 3 0 0 3 3 3 0 PPR repeat VbhA PF18495.1 PSC67015.1 - 0.13 12.1 2.7 1.3 8.9 0.1 3.9 4 0 0 4 4 4 0 Antitoxin VbhA AD PF09793.9 PSC67016.1 - 1.1e-13 51.2 0.0 1.6e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Anticodon-binding domain DUF1929 PF09118.11 PSC67017.1 - 1.1e-10 41.6 0.0 1.8e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyco_hydro_18 PF00704.28 PSC67018.1 - 2e-17 63.9 0.0 2.6e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 RVT_2 PF07727.14 PSC67019.1 - 3e-67 226.8 0.0 4.3e-67 226.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 PSC67019.1 - 1.1e-41 141.7 0.1 4.7e-24 84.6 0.0 3.4 3 0 0 3 3 3 3 gag-polypeptide of LTR copia-type rve PF00665.26 PSC67019.1 - 3.5e-24 85.3 0.0 1.1e-23 83.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 PSC67019.1 - 1.9e-09 37.2 0.0 3.8e-09 36.3 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4219 PF13961.6 PSC67019.1 - 4.6e-05 23.0 0.0 9.2e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) rve_3 PF13683.6 PSC67019.1 - 9.6e-05 22.1 0.0 0.00038 20.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain PRY PF13765.6 PSC67019.1 - 0.08 12.6 0.3 84 2.9 0.0 4.4 4 0 0 4 4 4 0 SPRY-associated domain Asp_protease_2 PF13650.6 PSC67019.1 - 0.087 13.5 0.1 0.68 10.6 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease Retrotran_gag_3 PF14244.6 PSC67019.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 PSC67019.1 - 0.14 11.9 2.0 0.3 10.9 2.0 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_3 PF13917.6 PSC67019.1 - 0.15 12.0 0.3 0.41 10.7 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle Crr6 PF08847.11 PSC67019.1 - 0.21 11.2 0.0 0.41 10.3 0.0 1.4 1 0 0 1 1 1 0 Chlororespiratory reduction 6 RVT_2 PF07727.14 PSC67021.1 - 1.2e-48 165.8 0.2 5.4e-18 65.5 0.0 3.1 2 1 1 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 PSC67021.1 - 9.6e-24 83.6 0.0 2.1e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 PSC67021.1 - 0.00032 20.9 0.0 0.001 19.2 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_3 PF13917.6 PSC67021.1 - 0.12 12.4 0.3 0.33 10.9 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 PSC67021.1 - 0.13 12.0 2.0 0.24 11.1 2.0 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_5 PF14787.6 PSC67021.1 - 0.32 10.7 2.5 0.76 9.5 2.5 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger RVT_2 PF07727.14 PSC67022.1 - 3.1e-44 151.5 0.1 2.7e-28 99.2 0.0 2.1 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Crr6 PF08847.11 PSC67022.1 - 0.036 13.7 0.0 0.073 12.7 0.0 1.5 1 0 0 1 1 1 0 Chlororespiratory reduction 6 Aa_trans PF01490.18 PSC67024.1 - 1.9e-35 122.4 0.0 4.8e-35 121.1 0.0 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Kinesin PF00225.23 PSC67025.1 - 1.3e-38 132.7 0.0 2.5e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain rve PF00665.26 PSC67025.1 - 3.8e-11 43.2 0.0 7.7e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Microtub_bd PF16796.5 PSC67025.1 - 1.1e-07 31.8 0.0 2.5e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding DUF4407 PF14362.6 PSC67025.1 - 0.0017 17.7 9.1 0.0017 17.7 9.1 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF4407) rve_3 PF13683.6 PSC67025.1 - 0.0071 16.1 0.4 0.027 14.3 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain Lzipper-MIP1 PF14389.6 PSC67025.1 - 0.22 11.9 7.0 9.7 6.6 0.1 2.7 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 SlyX PF04102.12 PSC67025.1 - 1.2 9.8 11.8 3.3 8.4 0.3 3.3 2 0 0 2 2 2 0 SlyX Aminotran_3 PF00202.21 PSC67026.1 - 3.2e-09 35.9 0.0 4.5e-09 35.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III RNase_PH_C PF03725.15 PSC67026.1 - 5.5e-06 26.3 0.0 8.2e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 RVT_2 PF07727.14 PSC67027.1 - 3.4e-46 157.8 0.1 3.5e-32 112.0 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 PSC67027.1 - 3e-24 85.3 0.0 5.6e-24 84.4 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 PSC67027.1 - 3.2e-24 85.4 0.0 2.4e-23 82.6 0.0 2.5 3 0 0 3 3 3 1 Integrase core domain DUF4219 PF13961.6 PSC67027.1 - 5.2e-05 22.8 0.0 0.00011 21.7 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) rve_3 PF13683.6 PSC67027.1 - 0.00012 21.8 0.0 0.00046 19.9 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain CxC4 PF18717.1 PSC67027.1 - 0.002 18.0 0.2 0.005 16.7 0.2 1.6 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases gag_pre-integrs PF13976.6 PSC67027.1 - 0.01 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 GAG-pre-integrase domain Retrotran_gag_3 PF14244.6 PSC67027.1 - 0.19 11.6 0.0 0.54 10.1 0.0 1.8 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Cupin_8 PF13621.6 PSC67028.1 - 1.1e-23 84.3 0.0 3.1e-23 82.8 0.0 1.6 2 0 0 2 2 2 1 Cupin-like domain PhoD PF09423.10 PSC67028.1 - 3e-15 56.1 0.0 9.6e-13 47.9 0.0 2.4 3 0 0 3 3 3 2 PhoD-like phosphatase WW PF00397.26 PSC67028.1 - 1.1e-08 35.0 0.2 2.6e-08 33.8 0.2 1.7 1 0 0 1 1 1 1 WW domain Cupin_4 PF08007.12 PSC67028.1 - 0.053 13.0 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein Cupin_2 PF07883.11 PSC67028.1 - 0.12 12.1 0.1 0.49 10.1 0.0 2.0 2 0 0 2 2 2 0 Cupin domain JmjC PF02373.22 PSC67028.1 - 0.14 12.6 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase TGBp3 PF02495.17 PSC67028.1 - 0.52 10.0 0.0 0.52 10.0 0.0 2.6 3 0 0 3 3 3 0 Triple gene block 3 Cupin_8 PF13621.6 PSC67029.1 - 1.4e-22 80.6 0.0 4.1e-22 79.1 0.0 1.6 2 0 0 2 2 2 1 Cupin-like domain PhoD PF09423.10 PSC67029.1 - 3.4e-15 55.9 0.0 1e-12 47.7 0.0 2.5 3 0 0 3 3 3 2 PhoD-like phosphatase WW PF00397.26 PSC67029.1 - 1.1e-08 35.0 0.2 2.7e-08 33.7 0.2 1.8 1 0 0 1 1 1 1 WW domain TGBp3 PF02495.17 PSC67029.1 - 0.15 11.8 2.1 0.55 9.9 0.0 2.3 2 0 0 2 2 2 0 Triple gene block 3 Cupin_4 PF08007.12 PSC67029.1 - 0.22 10.9 0.0 0.38 10.2 0.0 1.3 1 0 0 1 1 1 0 Cupin superfamily protein RVT_2 PF07727.14 PSC67030.1 - 1.2e-47 162.6 0.0 1e-32 113.7 0.0 2.2 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PSC67030.1 - 0.036 14.3 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain Phage_GPD PF05954.11 PSC67030.1 - 0.063 12.5 0.5 0.2 10.9 0.2 1.8 2 0 0 2 2 2 0 Phage late control gene D protein (GPD) Crr6 PF08847.11 PSC67030.1 - 0.08 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Chlororespiratory reduction 6 rve PF00665.26 PSC67031.1 - 5.8e-13 49.1 0.0 1.5e-12 47.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 PSC67031.1 - 8.1e-10 38.4 0.0 2.4e-09 36.9 0.0 1.9 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 PSC67031.1 - 0.0001 22.0 0.0 0.00026 20.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RVT_2 PF07727.14 PSC67031.1 - 0.00028 20.6 0.0 0.00043 20.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 PSC67031.1 - 0.14 12.8 0.0 0.44 11.2 0.0 1.8 1 0 0 1 1 1 0 Aspartyl protease RVT_2 PF07727.14 PSC67032.1 - 1.1e-72 244.5 0.0 1.5e-72 244.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PSC67032.1 - 2.9e-18 66.2 0.0 2e-16 60.3 0.0 2.9 2 1 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 PSC67032.1 - 1.6e-09 37.5 0.0 3.8e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 PSC67032.1 - 8.4e-05 22.3 0.1 0.00026 20.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Crr6 PF08847.11 PSC67032.1 - 0.14 11.8 0.0 0.28 10.8 0.0 1.4 1 0 0 1 1 1 0 Chlororespiratory reduction 6 CxC4 PF18717.1 PSC67033.1 - 0.00014 21.7 0.1 0.00029 20.7 0.1 1.5 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases HP1451_C PF18472.1 PSC67033.1 - 0.18 11.8 0.0 0.83 9.7 0.0 2.0 2 0 0 2 2 2 0 HP1451 C-terminal domain YabA PF06156.13 PSC67034.1 - 0.29 11.8 0.7 0.49 11.1 0.3 1.5 2 0 0 2 2 2 0 Initiation control protein YabA KDZ PF18758.1 PSC67035.1 - 3.5e-15 56.2 1.9 4.8e-15 55.8 1.9 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF2269 PF10027.9 PSC67035.1 - 0.0032 17.5 2.5 0.0038 17.3 0.6 1.8 1 1 1 2 2 2 1 Predicted integral membrane protein (DUF2269) F-box PF00646.33 PSC67036.1 - 0.00014 21.6 0.1 0.00048 19.9 0.1 2.0 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PSC67036.1 - 0.00037 20.3 0.5 0.0008 19.2 0.5 1.6 1 0 0 1 1 1 1 F-box-like Polyketide_cyc PF03364.20 PSC67036.1 - 0.01 16.1 0.1 0.018 15.3 0.1 1.4 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport RVT_2 PF07727.14 PSC67037.1 - 1.2e-09 38.2 0.0 1.8e-09 37.6 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PSC67037.1 - 1.7e-05 25.0 0.1 9.4e-05 22.6 0.0 2.2 3 0 0 3 3 3 1 Integrase core domain CxC4 PF18717.1 PSC67037.1 - 0.00054 19.8 0.2 0.0016 18.3 0.2 1.8 1 0 0 1 1 1 1 CxC4 like cysteine cluster associated with KDZ transposases gag_pre-integrs PF13976.6 PSC67037.1 - 0.003 17.4 0.0 0.0079 16.0 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain RVT_2 PF07727.14 PSC67038.1 - 1.1e-32 113.6 0.0 1.6e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Crr6 PF08847.11 PSC67038.1 - 0.051 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Chlororespiratory reduction 6 Pex14_N PF04695.13 PSC67039.1 - 0.07 13.8 16.5 0.082 13.6 16.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 PSC67039.1 - 0.28 11.1 10.5 0.31 11.0 10.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Nop14 PF04147.12 PSC67039.1 - 0.46 8.6 19.3 0.52 8.5 19.3 1.0 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.11 PSC67039.1 - 0.69 9.2 20.9 0.82 9.0 20.9 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RR_TM4-6 PF06459.12 PSC67039.1 - 1.7 8.4 17.5 2 8.2 17.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 PSC67039.1 - 1.8 8.5 6.1 2 8.4 6.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF5349 PF17298.2 PSC67039.1 - 2.4 7.8 9.9 2.7 7.6 9.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) TMEM214 PF10151.9 PSC67039.1 - 3.7 5.9 12.3 4.7 5.5 12.3 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Lin-8 PF03353.15 PSC67039.1 - 4.1 6.9 15.7 4.7 6.7 15.7 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RmuC PF02646.16 PSC67040.1 - 0.074 12.2 1.5 0.1 11.7 1.5 1.2 1 0 0 1 1 1 0 RmuC family DivIC PF04977.15 PSC67040.1 - 0.094 12.5 6.0 0.23 11.3 6.0 1.6 1 0 0 1 1 1 0 Septum formation initiator DUF4101 PF13355.6 PSC67041.1 - 1.5e-05 25.4 0.1 3.3e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4101) TPR_12 PF13424.6 PSC67041.1 - 6.9 7.0 10.0 8.9 6.7 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat RVT_2 PF07727.14 PSC67043.1 - 6.6e-90 301.0 0.0 4e-73 246.0 0.0 2.4 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PSC67043.1 - 2.6e-56 189.0 0.0 9.9e-24 83.8 0.0 3.9 3 0 0 3 3 3 3 Integrase core domain gag_pre-integrs PF13976.6 PSC67043.1 - 2.9e-24 84.7 0.1 4.3e-07 29.7 0.0 3.8 3 0 0 3 3 3 3 GAG-pre-integrase domain rve_3 PF13683.6 PSC67043.1 - 2.5e-11 43.2 0.1 0.00037 20.2 0.0 3.0 2 0 0 2 2 2 2 Integrase core domain Crr6 PF08847.11 PSC67043.1 - 6.1e-05 22.7 0.0 0.45 10.1 0.0 2.4 2 0 0 2 2 2 2 Chlororespiratory reduction 6 DAP_B PF07930.12 PSC67043.1 - 0.0042 17.1 0.1 4.5 7.2 0.0 2.4 2 0 0 2 2 2 2 D-aminopeptidase, domain B YdaS_antitoxin PF15943.5 PSC67043.1 - 0.035 14.0 0.0 17 5.4 0.0 2.7 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT Asp_protease_2 PF13650.6 PSC67043.1 - 0.13 13.0 0.1 0.99 10.1 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease RVT_3 PF13456.6 PSC67043.1 - 0.47 10.3 7.5 11 5.9 0.1 4.2 4 0 0 4 4 4 0 Reverse transcriptase-like rve PF00665.26 PSC67044.1 - 7.6e-16 58.4 0.0 3.5e-11 43.3 0.0 2.4 1 1 1 2 2 2 2 Integrase core domain gag_pre-integrs PF13976.6 PSC67044.1 - 5.3e-10 39.0 0.0 1.1e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 PSC67044.1 - 1.3e-09 37.8 0.0 1.9e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve_3 PF13683.6 PSC67044.1 - 0.0055 16.5 0.0 0.022 14.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain DUF4101 PF13355.6 PSC67045.1 - 3.2e-29 101.7 0.1 3.2e-29 101.7 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4101) TFIIA PF03153.13 PSC67045.1 - 0.0036 17.4 9.0 0.0048 16.9 9.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit IER PF05760.12 PSC67045.1 - 0.052 13.8 12.4 0.1 12.9 12.4 1.4 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF4746 PF15928.5 PSC67045.1 - 0.79 9.1 4.5 1.2 8.5 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Calpain_inhib PF00748.19 PSC67045.1 - 1.9 9.0 11.3 4.9 7.7 11.3 1.7 1 0 0 1 1 1 0 Calpain inhibitor Bactofilin PF04519.13 PSC67046.1 - 0.1 12.9 0.0 0.35 11.2 0.0 1.8 1 1 1 2 2 2 0 Polymer-forming cytoskeletal Yos1 PF08571.10 PSC67047.1 - 5.3e-24 84.3 0.1 5.8e-24 84.2 0.1 1.0 1 0 0 1 1 1 1 Yos1-like ClpS PF02617.17 PSC67048.1 - 3.1e-16 58.9 0.2 3.1e-16 58.9 0.2 2.0 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS Peptidase_M24 PF00557.24 PSC67049.1 - 1.6e-17 63.9 0.3 3.4e-17 62.8 0.2 1.5 1 1 0 1 1 1 1 Metallopeptidase family M24 G_glu_transpept PF01019.21 PSC67050.1 - 3.9e-40 138.1 1.8 5.7e-40 137.6 1.8 1.2 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase CRAL_TRIO PF00650.20 PSC67050.1 - 6.9e-24 84.4 0.1 8.2e-20 71.1 0.0 2.2 1 1 1 2 2 2 2 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PSC67050.1 - 0.099 12.8 0.4 0.21 11.8 0.4 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain UPF0220 PF05255.11 PSC67051.1 - 5.7e-25 87.8 1.9 7.4e-25 87.4 1.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF3611 PF12263.8 PSC67051.1 - 0.02 14.8 1.2 0.035 14.0 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) Kinocilin PF15033.6 PSC67051.1 - 3.2 7.4 5.1 14 5.3 4.5 2.0 1 1 1 2 2 2 0 Kinocilin protein DnaJ PF00226.31 PSC67052.1 - 2.5e-17 62.7 3.3 1.9e-15 56.7 2.1 2.4 2 0 0 2 2 2 2 DnaJ domain Sec63 PF02889.16 PSC67052.1 - 1.3e-15 57.3 0.0 1.6e-14 53.7 0.0 2.0 1 1 0 1 1 1 1 Sec63 Brl domain RVT_2 PF07727.14 PSC67053.1 - 8.6e-244 804.9 0.0 3.1e-56 190.7 0.0 7.2 5 2 2 7 7 7 7 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PSC67053.1 - 3.9e-51 172.2 0.0 4.8e-23 81.6 0.0 5.2 4 0 0 4 4 4 4 Integrase core domain rve_3 PF13683.6 PSC67053.1 - 6.3e-17 61.1 0.3 0.00078 19.2 0.0 4.1 3 0 0 3 3 3 3 Integrase core domain gag_pre-integrs PF13976.6 PSC67053.1 - 1.6e-15 56.7 0.0 4.3e-08 32.9 0.0 2.9 2 0 0 2 2 2 2 GAG-pre-integrase domain Crr6 PF08847.11 PSC67053.1 - 5.2e-08 32.7 0.0 0.81 9.3 0.0 3.6 3 0 0 3 3 3 3 Chlororespiratory reduction 6 YdaS_antitoxin PF15943.5 PSC67053.1 - 0.00064 19.5 0.0 23 4.9 0.0 3.5 3 0 0 3 3 3 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DAP_B PF07930.12 PSC67053.1 - 0.0018 18.3 0.2 6.2 6.8 0.0 3.2 3 0 0 3 3 3 2 D-aminopeptidase, domain B DUF4136 PF13590.6 PSC67053.1 - 0.0083 16.7 0.1 1.9e+02 2.6 0.0 4.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4136) MIF4G_like PF09088.11 PSC67053.1 - 0.01 15.6 0.0 64 3.2 0.0 4.9 5 0 0 5 5 5 0 MIF4G like DUF1659 PF07872.11 PSC67053.1 - 0.055 13.1 7.1 1.3e+02 2.3 0.0 5.4 5 0 0 5 5 5 0 Protein of unknown function (DUF1659) T6SS_Vgr PF13296.6 PSC67053.1 - 0.058 13.5 0.2 2.8e+02 1.7 0.0 4.4 4 0 0 4 4 4 0 Putative type VI secretion system Rhs element Vgr DotU PF09850.9 PSC67053.1 - 0.062 13.0 0.0 14 5.3 0.0 2.6 2 0 0 2 2 2 0 Type VI secretion system protein DotU Asp_protease_2 PF13650.6 PSC67053.1 - 0.075 13.7 3.6 1.4 9.6 0.0 4.7 6 0 0 6 6 6 0 Aspartyl protease DUF1619 PF07773.11 PSC67053.1 - 0.11 12.4 0.0 24 4.7 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1619) RVT_1 PF00078.27 PSC67053.1 - 0.19 11.2 0.4 38 3.7 0.0 3.1 3 0 0 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) CP12 PF02672.15 PSC67054.1 - 6.3e-17 62.1 5.6 1.4e-16 60.9 5.6 1.6 1 0 0 1 1 1 1 CP12 domain KH_1 PF00013.29 PSC67054.1 - 1.1e-16 60.4 0.6 1.9e-16 59.6 0.1 1.7 2 0 0 2 2 2 1 KH domain WW PF00397.26 PSC67054.1 - 9.8e-09 35.2 0.2 1.7e-08 34.4 0.2 1.4 1 0 0 1 1 1 1 WW domain KH_4 PF13083.6 PSC67054.1 - 1.7e-05 24.6 0.0 3.7e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 PSC67054.1 - 0.0016 18.2 0.1 0.0033 17.2 0.1 1.5 1 0 0 1 1 1 1 KH domain MOEP19 PF16005.5 PSC67054.1 - 0.033 14.2 0.0 0.059 13.4 0.0 1.3 1 0 0 1 1 1 0 KH-like RNA-binding domain TPR_1 PF00515.28 PSC67055.1 - 1.8e-14 52.8 9.6 7.6e-08 31.9 0.5 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PSC67055.1 - 8.4e-14 50.5 11.5 6.2e-07 29.0 0.7 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 PSC67055.1 - 1.2e-12 47.0 7.6 2.3e-06 27.4 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PSC67055.1 - 2.6e-11 43.0 12.2 4.3e-10 39.1 2.9 3.4 1 1 2 3 3 3 3 TPR repeat TPR_16 PF13432.6 PSC67055.1 - 7.2e-10 39.4 4.3 7.2e-10 39.4 4.3 4.5 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 PSC67055.1 - 1.2e-08 35.1 6.2 0.001 19.3 0.5 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 PSC67055.1 - 1.3e-07 31.1 2.5 0.00046 20.0 0.2 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 PSC67055.1 - 1.9e-06 27.8 5.5 0.0012 19.1 0.1 3.5 3 1 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 PSC67055.1 - 0.00036 21.0 2.8 0.00036 21.0 2.8 3.0 2 1 0 3 3 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 PSC67055.1 - 0.00042 20.1 4.5 0.072 13.0 0.3 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 PSC67055.1 - 0.00088 19.9 19.0 0.0015 19.2 0.0 4.7 3 2 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 PSC67055.1 - 0.0051 17.4 8.7 0.67 10.7 0.3 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 PSC67055.1 - 0.0074 16.4 0.2 0.031 14.4 0.2 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat FAT PF02259.23 PSC67055.1 - 0.015 14.5 0.5 0.021 14.0 0.5 1.2 1 0 0 1 1 1 0 FAT domain SHNi-TPR PF10516.9 PSC67055.1 - 0.15 11.5 0.8 0.92 9.0 0.0 2.4 2 0 0 2 2 2 0 SHNi-TPR BTAD PF03704.17 PSC67055.1 - 6.5 7.2 15.2 0.19 12.2 0.8 3.2 2 2 1 3 3 3 0 Bacterial transcriptional activator domain DUF812 PF05667.11 PSC67056.1 - 0.037 12.9 0.1 0.052 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF812) WHAMM-JMY_N PF15920.5 PSC67056.1 - 0.14 12.0 0.1 0.4 10.6 0.0 1.8 2 0 0 2 2 2 0 N-terminal of Junction-mediating and WASP homolog-associated DivIC PF04977.15 PSC67056.1 - 0.75 9.6 9.0 1.7 8.5 6.9 2.2 2 0 0 2 2 2 0 Septum formation initiator Pex14_N PF04695.13 PSC67058.1 - 0.07 13.8 16.5 0.082 13.6 16.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 PSC67058.1 - 0.28 11.1 10.5 0.31 11.0 10.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Nop14 PF04147.12 PSC67058.1 - 0.46 8.6 19.3 0.52 8.5 19.3 1.0 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.11 PSC67058.1 - 0.69 9.2 20.9 0.82 9.0 20.9 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) RR_TM4-6 PF06459.12 PSC67058.1 - 1.7 8.4 17.5 2 8.2 17.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 PSC67058.1 - 1.8 8.5 6.1 2 8.4 6.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF5349 PF17298.2 PSC67058.1 - 2.4 7.8 9.9 2.7 7.6 9.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) TMEM214 PF10151.9 PSC67058.1 - 3.7 5.9 12.3 4.7 5.5 12.3 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Lin-8 PF03353.15 PSC67058.1 - 4.1 6.9 15.7 4.7 6.7 15.7 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Pex14_N PF04695.13 PSC67059.1 - 0.073 13.7 16.5 0.085 13.5 16.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 PSC67059.1 - 0.4 10.6 10.9 0.44 10.5 10.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF5349 PF17298.2 PSC67059.1 - 0.51 10.0 7.8 0.5 10.1 7.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Nop53 PF07767.11 PSC67059.1 - 0.72 9.2 20.9 0.85 8.9 20.9 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Nop14 PF04147.12 PSC67059.1 - 1.3 7.1 20.7 1.5 7.0 20.7 1.0 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 PSC67059.1 - 1.7 8.4 17.5 2 8.2 17.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TMEM214 PF10151.9 PSC67059.1 - 3.8 5.8 12.3 4.9 5.5 12.3 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator Lin-8 PF03353.15 PSC67059.1 - 4.3 6.8 15.6 4.9 6.6 15.6 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Neur_chan_memb PF02932.16 PSC67059.1 - 9.2 6.2 8.3 11 6.0 8.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 PSC67059.1 - 9.6 4.9 19.3 11 4.7 19.3 1.0 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 PSC67060.1 - 0.43 10.5 17.8 0.88 9.5 17.8 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Syja_N PF02383.18 PSC67061.1 - 1.9e-22 80.0 0.0 5.7e-18 65.3 0.0 2.3 1 1 1 2 2 2 2 SacI homology domain WW PF00397.26 PSC67061.1 - 0.00048 20.2 0.1 0.0013 18.7 0.1 1.9 1 0 0 1 1 1 1 WW domain QWRF PF04484.12 PSC67061.1 - 0.94 9.2 3.8 2.6 7.7 3.8 1.7 1 0 0 1 1 1 0 QWRF family RVT_2 PF07727.14 PSC67063.1 - 1.2e-72 244.4 0.0 1.7e-72 244.0 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 PSC67063.1 - 2.6e-24 85.5 0.0 4.9e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 PSC67063.1 - 1.3e-23 83.4 0.0 4.4e-23 81.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain DUF4219 PF13961.6 PSC67063.1 - 2.1e-12 46.4 0.1 9.2e-05 22.0 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4219) gag_pre-integrs PF13976.6 PSC67063.1 - 5e-09 35.9 0.0 1.1e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotran_gag_3 PF14244.6 PSC67063.1 - 1.3e-05 24.9 0.0 0.27 11.1 0.0 2.7 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type rve_3 PF13683.6 PSC67063.1 - 0.00013 21.6 0.0 0.00039 20.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf-CCHC_3 PF13917.6 PSC67063.1 - 0.15 12.0 0.3 0.41 10.7 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 PSC67063.1 - 0.15 11.8 2.0 0.3 10.9 2.0 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_5 PF14787.6 PSC67063.1 - 0.33 10.7 2.5 0.94 9.2 2.5 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Syja_N PF02383.18 PSC67064.1 - 1e-22 80.9 0.0 3.6e-18 66.0 0.0 2.2 1 1 1 2 2 2 2 SacI homology domain WW PF00397.26 PSC67064.1 - 0.00042 20.3 0.1 0.0011 19.1 0.1 1.8 1 0 0 1 1 1 1 WW domain QWRF PF04484.12 PSC67064.1 - 0.93 9.2 3.8 2 8.1 3.8 1.5 1 0 0 1 1 1 0 QWRF family TFIIA PF03153.13 PSC67065.1 - 0.034 14.1 25.6 0.25 11.3 7.6 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF1929 PF09118.11 PSC67066.1 - 2.1e-13 50.4 0.0 3.4e-13 49.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Kelch_2 PF07646.15 PSC67066.1 - 0.02 14.9 0.4 0.15 12.0 0.1 2.4 2 1 0 2 2 2 0 Kelch motif RVT_2 PF07727.14 PSC67067.1 - 3.4e-176 583.5 0.0 3.4e-70 236.4 0.0 5.1 3 2 2 5 5 5 5 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PSC67067.1 - 1.2e-36 125.4 0.0 1.3e-23 83.4 0.0 4.1 2 1 1 3 3 3 3 Integrase core domain gag_pre-integrs PF13976.6 PSC67067.1 - 1.8e-19 69.4 0.0 9.7e-09 35.0 0.0 2.8 2 0 0 2 2 2 2 GAG-pre-integrase domain rve_3 PF13683.6 PSC67067.1 - 2.7e-10 39.9 0.1 0.00061 19.5 0.0 3.3 2 0 0 2 2 2 2 Integrase core domain Crr6 PF08847.11 PSC67067.1 - 1.6e-08 34.4 0.0 0.46 10.1 0.0 3.4 3 0 0 3 3 3 3 Chlororespiratory reduction 6 DUF1619 PF07773.11 PSC67067.1 - 6e-07 29.7 0.0 0.48 10.3 0.0 3.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1619) Retrotran_gag_2 PF14223.6 PSC67067.1 - 1.8e-06 27.7 0.0 3.7e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DAP_B PF07930.12 PSC67067.1 - 1.3e-05 25.2 0.3 5 7.1 0.0 3.4 3 0 0 3 3 3 3 D-aminopeptidase, domain B DUF4219 PF13961.6 PSC67067.1 - 6.4e-05 22.5 0.0 0.00014 21.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) YdaS_antitoxin PF15943.5 PSC67067.1 - 0.00032 20.5 0.0 19 5.2 0.0 3.6 3 0 0 3 3 3 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DotU PF09850.9 PSC67067.1 - 0.027 14.2 0.0 11 5.6 0.0 2.5 2 0 0 2 2 2 0 Type VI secretion system protein DotU RVT_1 PF00078.27 PSC67067.1 - 0.034 13.7 0.2 30 4.0 0.0 3.2 3 0 0 3 3 3 0 Reverse transcriptase (RNA-dependent DNA polymerase) DUF4136 PF13590.6 PSC67067.1 - 0.074 13.6 0.1 1.6e+02 2.9 0.0 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4136) HMA PF00403.26 PSC67068.1 - 4e-14 52.8 2.3 4.7e-14 52.6 2.3 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Pro_Al_protease PF02983.14 PSC67068.1 - 0.023 14.7 2.7 0.028 14.5 2.7 1.1 1 0 0 1 1 1 0 Alpha-lytic protease prodomain Flavodoxin_4 PF12682.7 PSC67068.1 - 0.043 13.5 0.2 0.047 13.4 0.2 1.1 1 0 0 1 1 1 0 Flavodoxin DUF211 PF02680.14 PSC67068.1 - 0.045 13.9 0.0 0.053 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Keratin_2_head PF16208.5 PSC67069.1 - 0.18 11.9 6.9 0.92 9.6 0.1 2.7 3 0 0 3 3 3 0 Keratin type II head F-box-like PF12937.7 PSC67070.1 - 1.2e-05 25.1 1.3 2.1e-05 24.3 1.3 1.5 1 0 0 1 1 1 1 F-box-like Cupin_8 PF13621.6 PSC67070.1 - 1.5e-05 24.9 0.0 0.00035 20.4 0.0 2.1 1 1 1 2 2 2 1 Cupin-like domain F-box PF00646.33 PSC67070.1 - 8.7e-05 22.3 0.4 0.00016 21.4 0.4 1.4 1 0 0 1 1 1 1 F-box domain JmjC PF02373.22 PSC67070.1 - 0.0027 18.1 0.2 0.0046 17.4 0.2 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase Robl_LC7 PF03259.17 PSC67071.1 - 1.3e-21 76.2 0.1 2.5e-21 75.2 0.1 1.5 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 PSC67071.1 - 0.044 13.7 0.0 0.077 12.9 0.0 1.3 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 RVT_2 PF07727.14 PSC67073.1 - 2.6e-61 207.3 0.0 5.3e-32 111.4 0.0 3.2 2 1 1 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 PSC67073.1 - 4.4e-39 133.3 0.0 8.6e-24 83.8 0.0 2.4 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type rve PF00665.26 PSC67073.1 - 1.4e-34 118.8 0.0 2.1e-23 82.7 0.0 3.9 2 1 1 3 3 3 3 Integrase core domain rve_3 PF13683.6 PSC67073.1 - 1.3e-10 40.9 0.1 0.00067 19.4 0.0 3.0 2 0 0 2 2 2 2 Integrase core domain gag_pre-integrs PF13976.6 PSC67073.1 - 3.5e-10 39.6 0.0 9.1e-09 35.1 0.0 2.5 2 0 0 2 2 2 1 GAG-pre-integrase domain Asp_protease_2 PF13650.6 PSC67073.1 - 4.9e-05 23.9 0.2 1.2 9.8 0.0 3.3 3 0 0 3 3 3 2 Aspartyl protease DUF4219 PF13961.6 PSC67073.1 - 8.2e-05 22.2 0.0 0.00016 21.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) PRY PF13765.6 PSC67073.1 - 0.025 14.2 0.0 83 2.9 0.0 4.9 4 0 0 4 4 4 0 SPRY-associated domain PD40 PF07676.12 PSC67073.1 - 0.052 13.5 0.3 21 5.2 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat gag-asp_proteas PF13975.6 PSC67073.1 - 0.053 14.1 0.0 42 4.8 0.0 3.4 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease zf-CCHC_3 PF13917.6 PSC67073.1 - 0.19 11.7 1.2 0.72 9.9 0.3 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 PSC67073.1 - 0.28 11.0 2.0 0.52 10.1 2.0 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_5 PF14787.6 PSC67073.1 - 3.4 7.5 7.3 1.6 8.5 2.5 2.6 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Alpha-L-AF_C PF06964.12 PSC67074.1 - 6.1e-14 52.5 1.7 2.4e-06 27.8 0.1 2.4 1 1 1 2 2 2 2 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 PSC67074.1 - 6.6e-05 23.2 0.0 0.00018 21.8 0.0 1.8 1 0 0 1 1 1 1 Carbohydrate binding domain MMR_HSR1 PF01926.23 PSC67074.1 - 0.074 13.1 0.7 13 5.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase AA_kinase PF00696.28 PSC67075.1 - 8.8e-06 25.5 0.1 2e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Amino acid kinase family Glyco_transf_8 PF01501.20 PSC67076.1 - 4.2e-08 33.1 0.0 1.6e-07 31.2 0.0 1.7 1 1 0 1 1 1 1 Glycosyl transferase family 8 Robl_LC7 PF03259.17 PSC67078.1 - 5.3e-22 77.4 0.1 1.4e-21 76.1 0.1 1.8 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 PSC67078.1 - 0.024 14.5 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 AcetylCoA_hyd_C PF13336.6 PSC67078.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Acetyl-CoA hydrolase/transferase C-terminal domain Kinesin PF00225.23 PSC67079.1 - 1.2e-16 60.6 0.0 2e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain DUF3138 PF11336.8 PSC67079.1 - 0.0029 16.3 10.3 0.0029 16.3 10.3 4.0 2 1 2 4 4 4 1 Protein of unknown function (DUF3138) Lzipper-MIP1 PF14389.6 PSC67079.1 - 0.035 14.4 4.1 12 6.3 0.0 2.7 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 ALMT PF11744.8 PSC67079.1 - 0.47 9.2 0.9 1.1 8.0 0.9 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter Spc24 PF08286.11 PSC67079.1 - 5.9 7.2 9.8 10 6.4 0.5 3.8 4 0 0 4 4 4 0 Spc24 subunit of Ndc80 AA_kinase PF00696.28 PSC67080.1 - 9.4e-09 35.2 0.7 6.4e-05 22.7 0.1 2.6 1 1 1 2 2 2 2 Amino acid kinase family Acetyltransf_7 PF13508.7 PSC67080.1 - 5.1e-06 26.8 0.1 1.3e-05 25.5 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PSC67080.1 - 5.3e-05 23.4 0.0 0.00015 22.0 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PSC67080.1 - 0.038 13.9 0.0 0.077 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PSC67080.1 - 0.06 13.4 0.0 0.27 11.3 0.0 2.1 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain CBM_4_9 PF02018.17 PSC67081.1 - 4e-05 23.9 0.0 8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain Polyketide_cyc PF03364.20 PSC67081.1 - 0.095 12.9 0.0 0.2 11.9 0.0 1.5 1 0 0 1 1 1 0 Polyketide cyclase / dehydrase and lipid transport Ephrin_rec_like PF07699.13 PSC67082.1 - 0.012 15.4 3.1 0.035 13.9 3.2 1.8 1 1 0 1 1 1 0 Putative ephrin-receptor like RRM_1 PF00076.22 PSC67083.1 - 0.062 13.1 0.0 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 6PGD PF00393.19 PSC67084.1 - 4.9e-120 400.3 0.0 7.4e-120 399.7 0.0 1.2 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain XRN_N PF03159.18 PSC67084.1 - 2.5e-79 266.1 0.0 1e-38 133.2 0.0 2.4 1 1 1 2 2 2 2 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 PSC67084.1 - 4.2e-36 124.9 0.0 1.4e-31 109.9 0.0 2.5 2 0 0 2 2 2 2 Xrn1 helical domain NAD_binding_2 PF03446.15 PSC67084.1 - 0.0016 18.6 0.1 0.0036 17.5 0.1 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Pox_VLTF3 PF04947.14 PSC67084.1 - 0.093 12.5 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like 4HBT PF03061.22 PSC67085.1 - 7.4e-06 26.2 0.0 1.2e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily CPL PF08144.11 PSC67086.1 - 1.3e-10 41.8 0.0 7.5e-07 29.6 0.0 4.3 3 1 1 4 4 4 1 CPL (NUC119) domain PUF PF00806.19 PSC67086.1 - 0.094 12.4 0.0 41 4.1 0.0 4.0 5 0 0 5 5 5 0 Pumilio-family RNA binding repeat RRM_1 PF00076.22 PSC67088.1 - 1.1e-18 66.9 0.0 2.1e-18 65.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PSC67088.1 - 0.0028 17.7 0.0 0.0054 16.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif RRM_8 PF11835.8 PSC67088.1 - 0.11 12.7 0.0 0.45 10.7 0.0 1.9 1 1 0 1 1 1 0 RRM-like domain Gln-synt_N_2 PF16952.5 PSC67088.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 2 0 0 2 2 2 0 Glutamine synthetase N-terminal domain RR_TM4-6 PF06459.12 PSC67088.1 - 2.3 8.0 6.7 2.7 7.8 6.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 EIF4E-T PF10477.9 PSC67088.1 - 9.2 4.9 32.9 10 4.8 32.9 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E CENP-F_leu_zip PF10473.9 PSC67089.1 - 0.0034 17.4 3.3 0.0034 17.4 3.3 6.0 2 2 4 6 6 6 2 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Tropomyosin PF00261.20 PSC67089.1 - 0.012 15.0 0.9 0.012 15.0 0.9 5.5 3 1 2 5 5 5 0 Tropomyosin DUF948 PF06103.11 PSC67089.1 - 3.8 7.8 14.6 0.81 10.0 0.4 4.7 5 1 1 6 6 6 0 Bacterial protein of unknown function (DUF948) Filament PF00038.21 PSC67089.1 - 7.9 6.0 61.2 0.65 9.5 7.0 4.7 1 1 3 4 4 4 0 Intermediate filament protein PUF PF00806.19 PSC67090.1 - 0.032 13.9 0.0 19 5.2 0.0 3.4 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat DUF2526 PF10735.9 PSC67090.1 - 0.21 11.8 1.6 0.4 10.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2526) DUF4101 PF13355.6 PSC67091.1 - 8.1e-29 100.4 0.1 8.1e-29 100.4 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF4101) TFIIA PF03153.13 PSC67091.1 - 0.085 12.8 12.1 0.13 12.2 12.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IER PF05760.12 PSC67091.1 - 0.15 12.3 12.4 0.27 11.5 12.4 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF4746 PF15928.5 PSC67091.1 - 1.8 7.9 4.5 2.7 7.3 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF3306 PF11748.8 PSC67091.1 - 3.7 8.5 15.9 10 7.0 15.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Calpain_inhib PF00748.19 PSC67091.1 - 4.6 7.7 11.4 12 6.4 11.4 1.6 1 0 0 1 1 1 0 Calpain inhibitor Syja_N PF02383.18 PSC67092.1 - 2.7e-11 43.4 0.0 9e-07 28.5 0.0 2.5 1 1 1 2 2 2 2 SacI homology domain WW PF00397.26 PSC67092.1 - 0.00036 20.5 0.1 0.00096 19.2 0.1 1.8 1 0 0 1 1 1 1 WW domain zf-CCHC PF00098.23 PSC67094.1 - 5.3e-20 70.5 17.3 4.6e-07 29.6 2.1 3.7 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_2 PF13696.6 PSC67094.1 - 1.2e-06 28.2 24.7 0.00089 19.0 0.8 3.8 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_5 PF14787.6 PSC67094.1 - 0.0036 17.0 26.2 0.33 10.7 1.7 3.6 2 1 1 3 3 3 3 GAG-polyprotein viral zinc-finger eIF3g PF12353.8 PSC67094.1 - 0.032 14.6 16.7 0.21 12.0 1.0 3.5 1 1 2 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.6 PSC67094.1 - 0.048 13.6 16.2 1.1 9.2 0.4 3.5 1 1 2 3 3 3 0 Zinc knuckle DUF4476 PF14771.6 PSC67094.1 - 0.15 12.4 0.0 0.37 11.1 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4476) zf-CCHC_4 PF14392.6 PSC67094.1 - 0.2 11.4 11.6 0.6 9.9 0.4 3.4 3 0 0 3 3 3 0 Zinc knuckle PALP PF00291.25 PSC67094.1 - 0.32 10.4 1.8 0.38 10.1 0.2 1.8 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme Thioredox_DsbH PF03190.15 PSC67095.1 - 3.1e-37 128.1 0.5 7e-37 126.9 0.5 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 PSC67095.1 - 1.8e-10 40.9 0.1 5.8e-10 39.2 0.0 1.9 2 0 0 2 2 2 1 Thioredoxin-like U-box PF04564.15 PSC67095.1 - 4.3e-07 30.0 0.0 9.6e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 U-box domain RVT_2 PF07727.14 PSC67096.1 - 0.00053 19.7 0.0 0.00073 19.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ku PF02735.16 PSC67098.1 - 4.4e-27 95.1 0.0 1.1e-14 54.6 0.0 2.3 1 1 1 2 2 2 2 Ku70/Ku80 beta-barrel domain SAP PF02037.27 PSC67098.1 - 1.3e-09 37.6 0.0 2.4e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 SAP domain Ku_C PF03730.14 PSC67098.1 - 8.2e-07 29.6 0.6 2.6e-06 28.0 0.6 1.8 1 1 0 1 1 1 1 Ku70/Ku80 C-terminal arm Ku_N PF03731.15 PSC67098.1 - 1.3e-06 28.4 0.0 2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ish1 PF10281.9 PSC67098.1 - 0.0088 16.3 0.2 0.029 14.7 0.0 2.0 2 0 0 2 2 2 1 Putative stress-responsive nuclear envelope protein WD40 PF00400.32 PSC67099.1 - 5.5e-30 103.0 18.8 9.7e-07 29.4 0.3 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC67099.1 - 4.2e-09 36.6 2.2 0.36 11.1 0.0 4.4 2 1 2 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain VID27 PF08553.10 PSC67099.1 - 0.0012 18.0 0.3 0.016 14.3 0.1 2.2 1 1 1 2 2 2 1 VID27 C-terminal WD40-like domain PQQ_2 PF13360.6 PSC67099.1 - 0.017 14.7 0.2 0.064 12.8 0.0 2.0 2 1 1 3 3 3 0 PQQ-like domain WD40_like PF17005.5 PSC67099.1 - 0.089 12.1 0.0 0.58 9.4 0.0 2.3 1 1 1 3 3 3 0 WD40-like domain CCB1 PF12046.8 PSC67100.1 - 8.9e-08 31.7 0.2 2.9e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Cofactor assembly of complex C subunit B DUF812 PF05667.11 PSC67100.1 - 3.5 6.4 18.9 9.9 4.9 18.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF3136 PF11334.8 PSC67101.1 - 0.036 13.9 0.1 1.4 8.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3136) RPAP2_Rtr1 PF04181.13 PSC67102.1 - 1.8e-10 41.0 0.0 3.2e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Rtr1/RPAP2 family CCDC53 PF10152.9 PSC67102.1 - 6.6 7.1 5.7 1.9 8.9 1.0 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex TFIIA PF03153.13 PSC67102.1 - 9.1 6.2 8.4 14 5.5 8.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Acetyltransf_7 PF13508.7 PSC67103.1 - 1.5e-06 28.6 0.1 3.5e-06 27.4 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PSC67103.1 - 2.3e-05 24.6 0.0 4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PSC67103.1 - 0.013 15.4 0.0 0.021 14.8 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PSC67103.1 - 0.02 15.0 0.0 0.07 13.2 0.0 1.8 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain AAA_22 PF13401.6 PSC67104.1 - 0.013 15.8 0.0 0.065 13.5 0.0 2.2 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 PSC67104.1 - 0.037 13.5 0.0 0.077 12.4 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 PSC67104.1 - 0.05 13.3 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Mg_chelatase PF01078.21 PSC67104.1 - 0.18 11.2 1.4 6.3 6.1 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Kinesin PF00225.23 PSC67105.1 - 1.2e-39 136.1 0.0 2.3e-39 135.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PSC67105.1 - 2.3e-07 30.8 0.0 4.6e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding ATP-grasp PF02222.22 PSC67105.1 - 0.15 11.6 0.1 0.39 10.3 0.1 1.7 1 0 0 1 1 1 0 ATP-grasp domain Lzipper-MIP1 PF14389.6 PSC67105.1 - 1.1 9.6 7.8 19 5.7 0.2 2.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Leu_zip PF15294.6 PSC67105.1 - 2.1 7.8 6.4 7.9 5.9 0.6 2.4 2 0 0 2 2 2 0 Leucine zipper Polysacc_synt_4 PF04669.13 PSC67106.1 - 1.2e-19 70.7 0.0 6.2e-18 65.0 0.0 2.3 1 1 0 1 1 1 1 Polysaccharide biosynthesis rve PF00665.26 PSC67107.1 - 4.9e-16 59.0 0.0 1e-15 58.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain NAD_binding_8 PF13450.6 PSC67108.1 - 5.5e-10 39.3 0.0 2.3e-09 37.4 0.0 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 PSC67108.1 - 7.7e-09 35.4 0.7 2.2e-05 24.0 0.1 3.1 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase Pyr_redox_2 PF07992.14 PSC67108.1 - 2e-06 27.3 0.0 0.015 14.5 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PSC67108.1 - 2e-06 27.6 0.2 0.00064 19.4 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 PSC67108.1 - 2e-05 24.6 0.6 0.15 12.1 0.1 2.8 3 0 0 3 3 3 2 FAD-NAD(P)-binding HI0933_like PF03486.14 PSC67108.1 - 0.004 15.9 0.2 0.72 8.5 0.1 2.1 2 0 0 2 2 2 2 HI0933-like protein Thi4 PF01946.17 PSC67108.1 - 0.1 11.8 0.2 0.21 10.8 0.2 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 PSC67108.1 - 0.17 10.9 0.1 0.32 10.0 0.1 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A OTU PF02338.19 PSC67109.1 - 1.2e-17 64.6 0.0 4.1e-17 62.9 0.0 1.7 1 1 0 1 1 1 1 OTU-like cysteine protease RNase_PH PF01138.21 PSC67110.1 - 3.2e-24 85.9 0.0 6.5e-24 84.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PSC67110.1 - 2.8e-09 36.9 0.0 8.2e-09 35.4 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 2 RVT_2 PF07727.14 PSC67111.1 - 3.3e-100 334.7 0.0 1.9e-56 191.4 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PSC67111.1 - 7.6e-25 87.4 0.0 3.3e-24 85.3 0.0 2.2 3 0 0 3 3 3 1 Integrase core domain Retrotran_gag_2 PF14223.6 PSC67111.1 - 2.5e-24 85.5 0.0 5.2e-24 84.5 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 PSC67111.1 - 1.7e-09 37.4 0.0 4.1e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 PSC67111.1 - 0.00015 21.5 0.0 0.00046 19.9 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DotU PF09850.9 PSC67111.1 - 0.013 15.2 0.0 7.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Type VI secretion system protein DotU Asp_protease_2 PF13650.6 PSC67111.1 - 0.077 13.7 0.1 0.74 10.5 0.0 2.5 2 0 0 2 2 2 0 Aspartyl protease RVT_1 PF00078.27 PSC67111.1 - 0.12 11.9 0.0 20 4.6 0.0 2.4 2 0 0 2 2 2 0 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_3 PF14244.6 PSC67111.1 - 0.17 11.7 0.0 0.54 10.1 0.0 1.9 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF1619 PF07773.11 PSC67111.1 - 0.24 11.3 0.0 13 5.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1619) Nab2p_Zf1 PF18260.1 PSC67113.1 - 0.091 12.7 0.6 11 6.0 0.0 3.2 3 0 0 3 3 3 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 DUF2857 PF11198.8 PSC67114.1 - 0.15 11.9 0.4 0.55 10.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2857) KR PF08659.10 PSC67115.1 - 5.9e-29 101.2 2.5 1.2e-28 100.2 2.5 1.5 1 0 0 1 1 1 1 KR domain PP-binding PF00550.25 PSC67115.1 - 1.8e-23 82.7 0.2 3.4e-11 43.3 0.1 2.5 2 0 0 2 2 2 2 Phosphopantetheine attachment site adh_short_C2 PF13561.6 PSC67115.1 - 6.9e-07 29.1 1.1 1.4e-06 28.0 1.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PSC67115.1 - 0.0015 18.0 0.7 0.0032 16.9 0.7 1.6 1 0 0 1 1 1 1 short chain dehydrogenase Nucleoporin2 PF04096.14 PSC67115.1 - 0.0052 16.9 0.0 0.0091 16.1 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase Syja_N PF02383.18 PSC67116.1 - 2.1e-33 116.0 0.0 1.4e-32 113.3 0.0 2.0 1 1 0 1 1 1 1 SacI homology domain WW PF00397.26 PSC67116.1 - 0.00034 20.6 0.1 0.001 19.1 0.1 1.9 1 0 0 1 1 1 1 WW domain Polyketide_cyc PF03364.20 PSC67118.1 - 2e-21 76.6 1.0 3.6e-21 75.7 1.0 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport LRR_8 PF13855.6 PSC67118.1 - 7.5e-08 32.0 21.8 1.2e-07 31.3 0.9 6.7 5 2 2 7 7 7 1 Leucine rich repeat LRR_4 PF12799.7 PSC67118.1 - 3.7e-07 30.3 14.9 0.0034 17.7 0.2 6.3 6 1 1 7 7 7 2 Leucine Rich repeats (2 copies) Polyketide_cyc2 PF10604.9 PSC67118.1 - 0.0001 22.6 0.5 0.0011 19.2 0.2 2.6 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport F-box PF00646.33 PSC67118.1 - 0.0011 18.7 0.1 0.0028 17.5 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PSC67118.1 - 0.0017 18.2 0.5 0.0046 16.8 0.5 1.8 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 PSC67118.1 - 0.087 13.4 16.8 5 8.1 0.1 6.6 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 PSC67118.1 - 0.68 10.1 21.4 1.1 9.5 0.2 6.8 7 0 0 7 7 7 0 Leucine Rich repeat UPF0220 PF05255.11 PSC67119.1 - 9.5e-15 54.5 1.5 2.2e-14 53.4 1.1 1.5 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0220) DUF3611 PF12263.8 PSC67119.1 - 0.016 15.1 0.8 0.016 15.1 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) VirB8 PF04335.13 PSC67119.1 - 0.74 9.6 1.9 1 9.1 0.0 1.8 2 0 0 2 2 2 0 VirB8 protein G_glu_transpept PF01019.21 PSC67120.1 - 1.1e-151 506.2 0.0 1.2e-151 506.0 0.0 1.0 1 0 0 1 1 1 1 Gamma-glutamyltranspeptidase CRAL_TRIO PF00650.20 PSC67121.1 - 3.4e-33 114.6 0.1 4.9e-33 114.1 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PSC67121.1 - 0.067 13.4 0.4 0.15 12.2 0.4 1.6 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 PSC67121.1 - 0.21 11.7 0.0 0.33 11.1 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain SLT PF01464.20 PSC67122.1 - 0.15 11.7 2.4 21 4.8 0.0 4.0 5 0 0 5 5 5 0 Transglycosylase SLT domain Carbam_trans_N PF02543.15 PSC67122.1 - 0.32 10.6 1.7 6.7 6.3 0.6 2.2 1 1 1 2 2 2 0 Carbamoyltransferase N-terminus AAA_9 PF12781.7 PSC67122.1 - 0.32 10.1 12.2 0.34 10.0 1.0 3.3 2 1 1 3 3 3 0 ATP-binding dynein motor region FUSC_2 PF13515.6 PSC67123.1 - 0.0032 17.6 1.4 0.0074 16.4 1.1 1.8 1 1 0 1 1 1 1 Fusaric acid resistance protein-like AAA_9 PF12781.7 PSC67123.1 - 1.4 8.0 17.6 0.72 8.9 1.1 4.0 2 1 2 4 4 4 0 ATP-binding dynein motor region DUF16 PF01519.16 PSC67123.1 - 8.4 6.9 11.4 4.7 7.8 0.8 3.5 2 1 1 3 3 3 0 Protein of unknown function DUF16 Peptidase_M76 PF09768.9 PSC67124.1 - 1.1e-36 126.2 5.7 4.9e-34 117.6 3.4 2.2 1 1 1 2 2 2 2 Peptidase M76 family MORN PF02493.20 PSC67124.1 - 1.9e-18 65.2 16.3 3.8e-07 29.6 1.5 4.1 3 0 0 3 3 3 3 MORN repeat Peptidase_M91 PF14891.6 PSC67124.1 - 0.023 15.0 0.0 0.038 14.3 0.0 1.3 1 0 0 1 1 1 0 Effector protein LRV PF01816.17 PSC67124.1 - 0.082 13.3 0.9 0.49 10.9 0.9 2.5 1 0 0 1 1 1 0 Leucine rich repeat variant Mem_trans PF03547.18 PSC67124.1 - 0.085 11.2 0.8 7.4 4.8 1.5 2.1 2 0 0 2 2 2 0 Membrane transport protein TspO_MBR PF03073.15 PSC67125.1 - 1.5e-37 128.7 11.1 3.6e-37 127.4 11.1 1.6 1 0 0 1 1 1 1 TspO/MBR family Fip1 PF05182.13 PSC67125.1 - 1.9e-16 59.3 0.0 3.1e-16 58.6 0.0 1.3 1 0 0 1 1 1 1 Fip1 motif Peptidase_M76 PF09768.9 PSC67126.1 - 6.9e-45 152.9 5.4 4.8e-42 143.6 3.0 2.1 1 1 1 2 2 2 2 Peptidase M76 family MORN PF02493.20 PSC67126.1 - 8.6e-17 59.9 16.1 2.1e-07 30.4 1.5 3.9 4 0 0 4 4 4 3 MORN repeat Peptidase_M91 PF14891.6 PSC67126.1 - 0.013 15.8 0.0 0.018 15.4 0.0 1.2 1 0 0 1 1 1 0 Effector protein BSP PF04450.12 PSC67126.1 - 0.21 11.3 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 Peptidase of plants and bacteria Mem_trans PF03547.18 PSC67126.1 - 2.6 6.3 4.3 3.8 5.8 4.3 1.2 1 0 0 1 1 1 0 Membrane transport protein LRV PF01816.17 PSC67126.1 - 7.8 7.1 9.0 0.27 11.7 0.9 3.1 2 0 0 2 2 2 0 Leucine rich repeat variant DUF4478 PF14793.6 PSC67127.1 - 0.07 13.0 0.7 0.07 13.0 0.7 1.8 2 0 0 2 2 2 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases TFIIA PF03153.13 PSC67127.1 - 5.1 7.0 24.6 6.7 6.6 24.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4478 PF14793.6 PSC67128.1 - 0.07 13.0 0.7 0.07 13.0 0.7 1.8 2 0 0 2 2 2 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases TFIIA PF03153.13 PSC67128.1 - 8.9 6.2 25.4 12 5.8 25.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SMC_N PF02463.19 PSC67130.1 - 2.2e-10 40.4 0.1 3.2e-10 39.8 0.1 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain RE_TdeIII PF09520.10 PSC67130.1 - 0.016 14.9 0.2 0.016 14.9 0.2 1.9 2 0 0 2 2 2 0 Type II restriction endonuclease, TdeIII DUF948 PF06103.11 PSC67130.1 - 0.93 9.8 13.1 2.1 8.7 2.9 3.9 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Bap31_Bap29_C PF18035.1 PSC67130.1 - 1.1 9.4 8.3 0.21 11.6 0.7 3.4 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain Abhydrolase_6 PF12697.7 PSC67131.1 - 1.4e-07 32.3 0.0 1.9e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family MOR2-PAG1_mid PF14228.6 PSC67131.1 - 0.14 9.7 0.0 0.18 9.4 0.0 1.1 1 0 0 1 1 1 0 Cell morphogenesis central region Hydrolase_4 PF12146.8 PSC67131.1 - 0.15 11.3 0.0 0.17 11.1 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 SBP PF03110.14 PSC67132.1 - 1.5e-19 70.0 7.7 1.5e-19 70.0 7.7 1.9 2 0 0 2 2 2 1 SBP domain E1-E2_ATPase PF00122.20 PSC67133.1 - 7.6e-28 97.2 0.7 1.5e-26 93.0 0.0 3.3 3 0 0 3 3 3 1 E1-E2 ATPase TPT PF03151.16 PSC67133.1 - 1.8e-23 83.3 21.5 3.2e-23 82.5 21.5 1.4 1 0 0 1 1 1 1 Triose-phosphate Transporter family Cation_ATPase_N PF00690.26 PSC67133.1 - 2.6e-11 43.0 0.0 7e-11 41.6 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 PSC67133.1 - 1.3e-06 28.9 1.0 6.8e-06 26.5 0.9 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase UAA PF08449.11 PSC67133.1 - 1.9e-05 24.1 20.2 3.8e-05 23.0 20.2 1.5 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 PSC67133.1 - 0.0097 16.1 12.5 0.0097 16.1 12.5 4.1 3 0 0 3 3 3 1 EamA-like transporter family Pkinase PF00069.25 PSC67135.1 - 3.1e-22 79.2 0.0 8.5e-15 54.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC67135.1 - 2.1e-11 43.6 0.0 3.2e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PSC67135.1 - 0.021 13.6 0.0 0.033 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 PSC67135.1 - 0.061 13.2 0.0 0.061 13.2 0.0 2.5 3 1 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 PSC67135.1 - 0.084 12.2 0.6 0.3 10.4 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PSC67135.1 - 0.2 11.2 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase eIF-3_zeta PF05091.12 PSC67136.1 - 1.1e-143 479.9 0.0 2.1e-143 479.1 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 PSC67136.1 - 0.14 11.7 0.0 0.32 10.5 0.0 1.5 1 1 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus Peptidase_S8 PF00082.22 PSC67137.1 - 1.2e-10 41.1 0.0 1.6e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Mito_fiss_reg PF05308.11 PSC67137.1 - 4 7.4 4.3 6.7 6.7 4.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 PSC67137.1 - 4.6 6.6 7.4 11 5.4 7.4 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 PSC67137.1 - 7.2 6.7 8.8 14 5.7 8.8 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 AMP-binding PF00501.28 PSC67138.1 - 2.2e-45 155.0 0.9 2.9e-31 108.5 0.0 2.0 2 0 0 2 2 2 2 AMP-binding enzyme Methyltransf_11 PF08241.12 PSC67139.1 - 3.7e-17 62.7 0.0 8.3e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC67139.1 - 4.2e-15 56.2 0.1 1.1e-14 54.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC67139.1 - 5.3e-11 43.1 0.0 8.9e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC67139.1 - 2.8e-09 36.7 0.0 4.4e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 PSC67139.1 - 6.8e-08 32.4 0.0 1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC67139.1 - 1.8e-06 27.9 0.0 3.2e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CBM_14 PF01607.24 PSC67139.1 - 0.0035 17.5 0.9 0.01 16.0 0.8 1.8 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain Methyltransf_29 PF03141.16 PSC67139.1 - 0.022 13.3 0.0 0.032 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_5 PF01795.19 PSC67139.1 - 0.074 12.6 0.0 0.15 11.5 0.0 1.4 2 0 0 2 2 2 0 MraW methylase family Aa_trans PF01490.18 PSC67140.1 - 2.3e-12 46.3 2.4 2.7e-12 46.1 2.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein AAA_22 PF13401.6 PSC67141.1 - 4.2e-06 27.1 0.0 0.00012 22.4 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA PF00004.29 PSC67141.1 - 1.7e-05 25.2 0.0 0.029 14.8 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Cdc6_C PF09079.11 PSC67141.1 - 4.8e-05 23.3 0.0 9.8e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 CDC6, C terminal winged helix domain AAA_lid_10 PF17872.1 PSC67141.1 - 0.017 15.3 0.2 0.038 14.1 0.2 1.6 1 0 0 1 1 1 0 AAA lid domain AAA_16 PF13191.6 PSC67141.1 - 0.6 10.5 0.0 0.6 10.5 0.0 4.2 4 1 0 4 4 4 0 AAA ATPase domain rve PF00665.26 PSC67142.1 - 5e-19 68.7 0.0 1e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC67142.1 - 0.0016 18.1 0.0 0.0039 16.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain KR PF08659.10 PSC67143.1 - 5.5e-29 101.4 2.5 1.2e-28 100.3 2.5 1.5 1 0 0 1 1 1 1 KR domain PP-binding PF00550.25 PSC67143.1 - 1.6e-20 73.2 0.1 2.9e-09 37.2 0.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site adh_short_C2 PF13561.6 PSC67143.1 - 1.3e-06 28.2 1.9 2.7e-06 27.1 1.9 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Nucleoporin2 PF04096.14 PSC67143.1 - 1.6e-05 25.0 0.0 2.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Nucleoporin autopeptidase adh_short PF00106.25 PSC67143.1 - 0.0016 18.0 1.1 0.0031 17.0 0.6 1.6 1 1 0 1 1 1 1 short chain dehydrogenase Pkinase PF00069.25 PSC67144.1 - 2.6e-36 125.3 0.0 1.2e-35 123.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC67144.1 - 8.4e-34 117.0 0.0 3e-33 115.2 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 PSC67144.1 - 2.3e-06 27.8 1.3 0.043 14.2 0.0 5.1 5 1 2 7 7 7 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC67144.1 - 5.7e-05 22.8 7.7 0.007 16.1 0.3 5.3 6 0 0 6 6 6 1 Leucine rich repeat LRR_6 PF13516.6 PSC67144.1 - 0.0011 18.9 1.0 23 5.4 0.1 4.4 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 PSC67144.1 - 0.023 15.2 2.0 12 6.9 0.2 4.8 4 0 0 4 4 4 0 Leucine Rich Repeat LRRNT_2 PF08263.12 PSC67144.1 - 0.034 14.4 0.1 0.092 13.1 0.1 1.8 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain AAA_lid_2 PF17863.1 PSC67144.1 - 0.062 13.2 0.3 0.062 13.2 0.3 3.5 3 0 0 3 3 3 0 AAA lid domain Pkinase_fungal PF17667.1 PSC67144.1 - 0.14 10.9 0.0 0.14 10.9 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase WW PF00397.26 PSC67145.1 - 0.00043 20.3 0.1 0.0012 18.9 0.1 1.8 1 0 0 1 1 1 1 WW domain rve PF00665.26 PSC67146.1 - 3.8e-18 65.8 0.0 8.2e-18 64.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Peptidase_M54 PF07998.11 PSC67146.1 - 1.1e-14 54.9 0.0 1.7e-14 54.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M54 Peptidase_M10 PF00413.24 PSC67146.1 - 0.0062 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Matrixin rve_3 PF13683.6 PSC67146.1 - 0.026 14.3 0.0 0.069 12.9 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Metallopep PF12044.8 PSC67146.1 - 0.098 11.2 0.7 0.18 10.4 0.7 1.3 1 0 0 1 1 1 0 Putative peptidase family Peptidase_M43 PF05572.13 PSC67146.1 - 0.19 11.7 0.1 0.4 10.6 0.1 1.4 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A DUF1990 PF09348.10 PSC67147.1 - 1.7e-19 70.4 0.1 2.1e-19 70.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1990) VPR PF00522.18 PSC67148.1 - 0.12 12.4 0.0 0.24 11.5 0.0 1.6 1 1 0 1 1 1 0 VPR/VPX protein DUF4101 PF13355.6 PSC67149.1 - 9.1e-29 100.3 0.1 2.1e-28 99.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4101) DUF3396 PF11876.8 PSC67149.1 - 0.00035 20.1 7.8 21 4.5 0.1 5.4 5 0 0 5 5 5 4 Protein of unknown function (DUF3396) Nudc_N PF14050.6 PSC67149.1 - 0.11 12.5 7.8 1.6e+02 2.4 0.0 5.1 5 0 0 5 5 5 0 N-terminal conserved domain of Nudc. SLC3A2_N PF16028.5 PSC67149.1 - 0.12 12.0 5.5 13 5.4 0.1 5.9 5 0 0 5 5 5 0 Solute carrier family 3 member 2 N-terminus TFIIA PF03153.13 PSC67149.1 - 0.26 11.2 12.3 0.41 10.6 12.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit IER PF05760.12 PSC67149.1 - 0.4 10.9 12.4 0.7 10.1 12.4 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) DUF4746 PF15928.5 PSC67149.1 - 4 6.8 4.5 6.6 6.1 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) CBM53 PF16760.5 PSC67151.1 - 1.4e-48 163.4 0.0 6.6e-18 65.1 0.0 3.7 3 0 0 3 3 3 3 Starch/carbohydrate-binding module (family 53) Glyco_transf_5 PF08323.11 PSC67151.1 - 8e-44 150.2 0.1 2.5e-41 142.0 0.0 2.7 2 1 0 2 2 2 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 PSC67151.1 - 5.6e-10 39.5 0.0 1.8e-09 37.8 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 PSC67151.1 - 5.7e-08 32.5 0.0 1.1e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PSC67151.1 - 4.2e-06 27.2 0.0 8.7e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 PSC67151.1 - 1.5e-05 25.5 0.5 0.00024 21.6 0.0 3.1 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Coprogen_oxidas PF01218.18 PSC67153.1 - 3.9e-127 423.0 1.1 4.4e-127 422.9 1.1 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase Xpo1 PF08389.12 PSC67154.1 - 1.5e-31 109.5 0.0 1.7e-30 106.1 0.0 2.6 2 0 0 2 2 2 1 Exportin 1-like protein Usp PF00582.26 PSC67154.1 - 0.0009 19.8 1.1 0.014 15.9 0.0 3.4 2 1 0 2 2 2 1 Universal stress protein family HEAT PF02985.22 PSC67154.1 - 0.0091 16.2 7.8 7.8 7.1 0.1 6.3 7 0 0 7 7 7 2 HEAT repeat bZIP_1 PF00170.21 PSC67155.1 - 1.8e-05 24.8 12.2 0.00013 22.0 6.5 2.5 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 PSC67155.1 - 0.00038 20.5 10.4 0.0004 20.4 8.5 2.0 1 1 0 1 1 1 1 Basic region leucine zipper CENP-R PF06729.12 PSC67155.1 - 0.066 13.1 1.7 0.77 9.7 0.4 2.2 2 0 0 2 2 2 0 Kinetochore component, CENP-R Sigma70_ner PF04546.13 PSC67155.1 - 0.098 12.5 3.1 2.6 7.9 0.1 2.2 2 0 0 2 2 2 0 Sigma-70, non-essential region DUF4110 PF13422.6 PSC67155.1 - 0.15 12.2 1.5 0.57 10.3 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) DUF641 PF04859.12 PSC67155.1 - 5.8 7.3 9.5 1.1 9.6 3.6 2.1 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) GST_N_2 PF13409.6 PSC67156.1 - 3.1e-16 59.4 0.0 7.6e-16 58.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PSC67156.1 - 1.9e-13 50.2 0.1 5.8e-13 48.7 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PSC67156.1 - 1.1e-08 35.2 0.1 1.9e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PSC67156.1 - 0.00027 21.3 0.0 0.081 13.4 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PSC67156.1 - 0.00037 20.7 0.0 0.00072 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 PSC67156.1 - 0.0041 16.9 0.0 0.0077 16.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain INT_SG_DDX_CT_C PF15300.6 PSC67156.1 - 0.031 14.1 0.0 0.74 9.7 0.0 2.2 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus Methyltransf_11 PF08241.12 PSC67157.1 - 2.2e-11 44.3 0.0 4.3e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MORN PF02493.20 PSC67157.1 - 2.3e-09 36.6 5.3 0.0041 16.9 0.7 3.7 3 0 0 3 3 3 3 MORN repeat Methyltransf_25 PF13649.6 PSC67157.1 - 8.2e-09 36.1 0.0 1.7e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC67157.1 - 1.1e-07 32.5 0.0 3.6e-07 30.8 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC67157.1 - 1.8e-07 31.2 0.0 2.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC67157.1 - 0.0006 19.2 0.0 0.00089 18.6 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 PSC67157.1 - 0.0012 18.7 0.0 0.0051 16.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain FA_desaturase_2 PF03405.14 PSC67158.1 - 1.5e-05 24.1 0.1 2.1e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Fatty acid desaturase FoP_duplication PF13865.6 PSC67159.1 - 1 9.9 10.0 2 9.0 10.0 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 BATS PF06968.13 PSC67160.1 - 1.5e-25 89.1 0.0 3.4e-25 88.0 0.0 1.6 2 0 0 2 2 2 1 Biotin and Thiamin Synthesis associated domain YEATS PF03366.16 PSC67161.1 - 4.6e-14 52.2 0.0 8e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 YEATS family Rhodanese PF00581.20 PSC67161.1 - 1.4e-10 41.7 0.0 2.5e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain Chorion_3 PF05387.11 PSC67161.1 - 0.0039 16.9 2.9 0.0058 16.3 2.9 1.2 1 0 0 1 1 1 1 Chorion family 3 Response_reg PF00072.24 PSC67162.1 - 2.8e-06 27.5 0.0 6.4e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain Imm5 PF14423.6 PSC67162.1 - 0.12 12.5 0.3 0.22 11.7 0.3 1.4 1 0 0 1 1 1 0 Immunity protein Imm5 Aminotran_3 PF00202.21 PSC67163.1 - 1.5e-11 43.6 0.0 1.7e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Chromo PF00385.24 PSC67164.1 - 0.0011 18.8 0.1 0.0011 18.8 0.1 1.6 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Mut7-C PF01927.16 PSC67164.1 - 0.024 14.8 0.1 0.041 14.0 0.1 1.3 1 0 0 1 1 1 0 Mut7-C RNAse domain Zn-C2H2_12 PF18112.1 PSC67164.1 - 0.17 12.4 4.4 11 6.6 0.1 4.2 4 0 0 4 4 4 0 Autophagy receptor zinc finger-C2H2 domain KDZ PF18758.1 PSC67165.1 - 1.8e-07 31.0 0.7 2.4e-07 30.6 0.7 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Pkinase PF00069.25 PSC67166.1 - 8.3e-47 159.8 0.0 2.4e-46 158.2 0.0 1.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC67166.1 - 3.9e-22 78.8 0.0 6.4e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC67166.1 - 0.0035 16.7 0.0 0.0064 15.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Fes1 PF08609.10 PSC67166.1 - 0.085 13.7 0.0 10 7.1 0.0 2.7 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 Trimer_CC PF08954.11 PSC67166.1 - 0.15 11.7 0.1 0.15 11.7 0.1 2.7 3 0 0 3 3 3 0 Trimerisation motif Aa_trans PF01490.18 PSC67167.1 - 1.5e-43 149.0 19.6 1.9e-43 148.7 19.6 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein OHCU_decarbox PF09349.10 PSC67168.1 - 6.1e-26 91.8 0.0 7.3e-26 91.5 0.0 1.0 1 0 0 1 1 1 1 OHCU decarboxylase Abhydrolase_1 PF00561.20 PSC67169.1 - 3.8e-10 39.8 0.0 7.6e-08 32.3 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC67169.1 - 5.9e-06 25.7 0.0 0.00018 20.9 0.0 2.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Ribosomal_L7Ae PF01248.26 PSC67169.1 - 0.00018 21.1 0.1 0.00046 19.9 0.1 1.6 1 1 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CCDC50_N PF15295.6 PSC67169.1 - 0.0017 18.5 12.5 0.0047 17.1 12.5 1.7 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 50 N-terminus zf-C2H2_jaz PF12171.8 PSC67169.1 - 0.037 14.3 0.8 0.09 13.1 0.8 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Dev_Cell_Death PF10539.9 PSC67169.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 Development and cell death domain Cdd1 PF11731.8 PSC67169.1 - 0.16 12.2 0.0 0.45 10.8 0.0 1.7 1 0 0 1 1 1 0 Pathogenicity locus DUF2458 PF10454.9 PSC67169.1 - 1.2 8.8 5.2 2.5 7.7 5.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2458) rve PF00665.26 PSC67170.1 - 2.3e-18 66.5 0.0 4.7e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC67170.1 - 0.015 15.0 0.0 0.042 13.6 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain CarboxypepD_reg PF13620.6 PSC67170.1 - 0.36 11.1 1.1 4.4 7.6 0.1 2.5 2 0 0 2 2 2 0 Carboxypeptidase regulatory-like domain eIF-3_zeta PF05091.12 PSC67171.1 - 1.9e-116 390.1 0.0 3.5e-113 379.3 0.0 2.5 1 1 1 2 2 2 2 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 PSC67171.1 - 0.24 10.9 0.0 2.5 7.5 0.0 2.0 1 1 0 1 1 1 0 NMDA receptor-regulated gene protein 2 C-terminus WD40 PF00400.32 PSC67172.1 - 1.9e-26 91.8 12.2 5.3e-08 33.4 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC67172.1 - 2.4e-20 72.6 2.2 2.1e-06 27.9 0.3 4.5 3 2 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PSC67172.1 - 3.1e-07 30.5 0.0 0.037 13.9 0.0 2.5 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PSC67172.1 - 0.0011 18.0 0.4 0.051 12.5 0.2 3.3 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein DPPIV_N PF00930.21 PSC67172.1 - 0.0023 16.7 0.0 0.75 8.5 0.0 2.8 2 1 1 3 3 3 2 Dipeptidyl peptidase IV (DPP IV) N-terminal region Transthyretin PF00576.21 PSC67173.1 - 3.5e-31 108.2 0.0 5.5e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.6 PSC67173.1 - 0.00047 20.4 0.2 0.0012 19.1 0.2 1.8 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain Transthyretin PF00576.21 PSC67174.1 - 3.2e-31 108.3 0.0 4.6e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.6 PSC67174.1 - 0.00039 20.6 0.2 0.00095 19.4 0.2 1.8 1 1 0 1 1 1 1 Carboxypeptidase regulatory-like domain TIM PF00121.18 PSC67175.1 - 1.7e-85 286.3 0.0 3.3e-85 285.3 0.0 1.5 1 0 0 1 1 1 1 Triosephosphate isomerase ORC4_C PF14629.6 PSC67175.1 - 3.9e-18 65.6 0.0 8.4e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA_16 PF13191.6 PSC67175.1 - 7.4e-12 46.0 0.1 7.4e-12 46.0 0.1 3.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PSC67175.1 - 2.4e-07 31.1 0.0 7.5e-07 29.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 PSC67175.1 - 3.8e-06 27.3 0.1 1.1e-05 25.9 0.1 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 PSC67175.1 - 1.9e-05 24.2 0.2 6.7e-05 22.4 0.3 1.8 2 0 0 2 2 2 1 Bacterial TniB protein NACHT PF05729.12 PSC67175.1 - 5.4e-05 23.2 0.0 0.00013 21.9 0.0 1.7 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 PSC67175.1 - 0.091 12.7 0.0 0.21 11.4 0.0 1.5 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea Peptidase_M24 PF00557.24 PSC67177.1 - 3.2e-11 43.3 2.4 4.2e-08 33.1 0.1 2.9 1 1 2 3 3 3 2 Metallopeptidase family M24 ClpS PF02617.17 PSC67178.1 - 3.1e-16 58.9 0.2 3.1e-16 58.9 0.2 2.0 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS Yos1 PF08571.10 PSC67179.1 - 5.3e-24 84.3 0.1 5.8e-24 84.2 0.1 1.0 1 0 0 1 1 1 1 Yos1-like Sas10_Utp3 PF04000.15 PSC67180.1 - 0.013 16.1 0.2 0.022 15.4 0.2 1.4 1 0 0 1 1 1 0 Sas10/Utp3/C1D family Herpes_BLLF1 PF05109.13 PSC67180.1 - 0.12 10.3 0.8 0.15 10.0 0.8 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) TetR_C_34 PF17929.1 PSC67180.1 - 0.16 12.1 3.0 0.29 11.3 0.1 2.3 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Peptidase_M24 PF00557.24 PSC67181.1 - 1.3e-22 80.6 0.9 1.8e-22 80.0 0.9 1.4 1 1 0 1 1 1 1 Metallopeptidase family M24 TPR_11 PF13414.6 PSC67182.1 - 0.00014 21.5 0.4 0.0058 16.3 0.1 2.6 2 0 0 2 2 2 1 TPR repeat WD40 PF00400.32 PSC67182.1 - 0.017 15.9 0.0 7.6 7.6 0.0 2.7 2 0 0 2 2 2 0 WD domain, G-beta repeat TPR_17 PF13431.6 PSC67182.1 - 0.027 14.8 1.0 3.1 8.4 0.1 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Branch PF02485.21 PSC67183.1 - 2.4e-43 148.5 0.1 3.2e-43 148.0 0.1 1.1 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Glyco_hydro_16 PF00722.21 PSC67185.1 - 5.5e-08 32.5 0.0 8.5e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Clathrin PF00637.20 PSC67185.1 - 9.4e-06 25.6 0.0 1.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Region in Clathrin and VPS Branch PF02485.21 PSC67186.1 - 1.5e-45 155.7 0.0 2.1e-45 155.2 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme TFIIA PF03153.13 PSC67186.1 - 0.029 14.4 8.0 0.066 13.2 8.0 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Endomucin PF07010.12 PSC67186.1 - 0.19 11.7 1.1 0.32 10.9 1.1 1.4 1 0 0 1 1 1 0 Endomucin Fasciclin PF02469.22 PSC67187.1 - 1.8e-14 54.1 0.2 3.9e-14 53.0 0.2 1.6 1 0 0 1 1 1 1 Fasciclin domain Pkinase PF00069.25 PSC67188.1 - 2.7e-28 99.1 0.0 3.6e-28 98.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC67188.1 - 2.4e-20 72.9 0.0 3.5e-20 72.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PSC67188.1 - 5.1e-09 35.8 0.1 8.7e-06 25.4 0.0 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PSC67188.1 - 9.8e-05 22.7 0.1 0.011 16.1 0.0 2.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) APH PF01636.23 PSC67188.1 - 0.0026 17.7 0.2 0.0068 16.3 0.2 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PSC67188.1 - 0.064 12.0 0.0 0.094 11.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 PSC67188.1 - 0.095 12.3 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 PSC67188.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UL2 PF08196.11 PSC67188.1 - 0.3 11.1 0.9 2.5 8.1 0.1 2.3 2 0 0 2 2 2 0 UL2 protein DEC-1_N PF04625.13 PSC67188.1 - 1.1 8.2 4.0 1.9 7.4 4.0 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Pkinase PF00069.25 PSC67189.1 - 5.8e-29 101.3 0.0 7.9e-29 100.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC67189.1 - 1.4e-20 73.6 0.0 2.1e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PSC67189.1 - 4.5e-09 36.0 0.1 8.1e-06 25.5 0.0 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PSC67189.1 - 8.5e-05 22.8 0.1 0.011 16.2 0.0 2.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) APH PF01636.23 PSC67189.1 - 0.0025 17.8 0.2 0.0052 16.7 0.2 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PSC67189.1 - 0.06 12.1 0.0 0.088 11.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 PSC67189.1 - 0.087 12.4 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Kdo PF06293.14 PSC67189.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family UL2 PF08196.11 PSC67189.1 - 0.27 11.2 0.9 2.3 8.2 0.1 2.3 2 0 0 2 2 2 0 UL2 protein DEC-1_N PF04625.13 PSC67189.1 - 1 8.3 4.0 1.7 7.6 4.0 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region FAD_binding_7 PF03441.14 PSC67190.1 - 3.8e-39 134.3 1.9 4.7e-39 134.0 1.9 1.1 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase CLP_protease PF00574.23 PSC67191.1 - 1.5e-40 139.0 0.0 3e-40 138.1 0.0 1.4 1 1 0 1 1 1 1 Clp protease Peptidase_S49 PF01343.18 PSC67191.1 - 0.066 13.2 0.0 0.16 11.9 0.0 1.6 1 0 0 1 1 1 0 Peptidase family S49 KfrB PF18790.1 PSC67191.1 - 0.13 12.5 0.0 0.3 11.4 0.0 1.6 1 0 0 1 1 1 0 KfrB protein PCMT PF01135.19 PSC67192.1 - 1.4e-51 175.2 0.0 3.2e-34 118.5 0.0 2.3 2 0 0 2 2 2 2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 PSC67192.1 - 0.00011 22.0 0.0 0.00063 19.6 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain GCD14 PF08704.10 PSC67192.1 - 0.00013 21.7 0.0 0.006 16.3 0.0 2.3 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_32 PF13679.6 PSC67192.1 - 0.00019 21.5 0.0 0.00042 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PSC67192.1 - 0.00024 20.6 0.0 0.0004 19.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 PSC67192.1 - 0.0017 18.2 0.0 0.0038 17.1 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 PSC67192.1 - 0.008 15.3 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 PSC67192.1 - 0.012 16.3 0.4 0.55 10.9 0.2 3.0 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_25 PF13649.6 PSC67192.1 - 0.016 15.9 0.1 0.092 13.5 0.1 2.4 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 PSC67192.1 - 0.037 13.4 0.0 0.23 10.8 0.0 2.1 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family MTS PF05175.14 PSC67192.1 - 0.063 12.8 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Fibrillarin PF01269.17 PSC67192.1 - 0.15 11.2 0.0 0.26 10.4 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin MetW PF07021.12 PSC67192.1 - 0.15 11.6 0.1 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_3 PF01596.17 PSC67192.1 - 0.19 10.9 0.0 0.54 9.4 0.0 1.6 1 1 1 2 2 2 0 O-methyltransferase Peptidase_M20 PF01546.28 PSC67193.1 - 2.3e-14 53.6 0.0 1e-13 51.5 0.0 1.9 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PSC67193.1 - 3.4e-06 26.9 0.3 7.5e-06 25.8 0.3 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain PCMT PF01135.19 PSC67195.1 - 2.1e-56 191.0 0.0 4.5e-56 189.9 0.0 1.5 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.10 PSC67195.1 - 5.5e-05 23.0 0.0 0.0031 17.2 0.0 2.1 2 0 0 2 2 2 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 PSC67195.1 - 7.8e-05 22.5 0.0 0.00034 20.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_32 PF13679.6 PSC67195.1 - 0.00013 22.0 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PSC67195.1 - 0.00014 21.4 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 PSC67195.1 - 0.0011 18.8 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC67195.1 - 0.0024 18.6 0.1 0.01 16.5 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.17 PSC67195.1 - 0.0092 15.2 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase RrnaAD PF00398.20 PSC67195.1 - 0.027 13.6 0.0 0.038 13.1 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.12 PSC67195.1 - 0.028 15.1 0.4 0.13 12.9 0.3 2.3 2 1 0 2 2 1 0 Methyltransferase domain MTS PF05175.14 PSC67195.1 - 0.035 13.7 0.1 0.072 12.6 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Ubie_methyltran PF01209.18 PSC67195.1 - 0.06 12.7 0.0 0.098 12.0 0.0 1.5 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family MetW PF07021.12 PSC67195.1 - 0.066 12.8 0.1 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Fibrillarin PF01269.17 PSC67195.1 - 0.087 11.9 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin DUF3880 PF12996.7 PSC67195.1 - 0.14 12.2 0.6 1.7 8.8 0.0 2.6 3 0 0 3 3 3 0 DUF based on E. rectale Gene description (DUF3880) KOW PF00467.29 PSC67195.1 - 0.36 10.9 3.2 0.9 9.6 0.5 2.7 2 0 0 2 2 2 0 KOW motif WD40 PF00400.32 PSC67197.1 - 2.6e-10 40.7 0.1 9.4e-06 26.3 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat MutS_I PF01624.20 PSC67198.1 - 4.6e-14 52.6 0.0 9.4e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 MutS domain I WD40 PF00400.32 PSC67199.1 - 3.4e-10 40.3 0.1 1.1e-05 26.1 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat MutS_V PF00488.21 PSC67200.1 - 7.4e-41 140.2 0.0 6e-37 127.5 0.0 2.4 2 0 0 2 2 2 2 MutS domain V MutS_I PF01624.20 PSC67200.1 - 1e-13 51.5 0.0 2.1e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain I AAA_29 PF13555.6 PSC67200.1 - 0.001 18.8 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 PSC67200.1 - 0.0055 17.2 0.0 0.0096 16.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 PSC67200.1 - 0.062 12.9 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain GIY-YIG PF01541.24 PSC67200.1 - 0.099 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 GIY-YIG catalytic domain UPF0020 PF01170.18 PSC67201.1 - 1e-12 48.2 0.1 1.1e-10 41.6 0.1 2.4 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 PSC67201.1 - 3.8e-06 26.8 0.0 0.00012 21.9 0.0 2.2 2 0 0 2 2 2 1 DNA methylase MethyltransfD12 PF02086.15 PSC67201.1 - 0.13 11.9 0.0 0.59 9.8 0.0 1.9 2 0 0 2 2 2 0 D12 class N6 adenine-specific DNA methyltransferase PP-binding PF00550.25 PSC67203.1 - 9.7e-12 45.1 0.0 1.3e-11 44.6 0.0 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF836 PF05768.14 PSC67204.1 - 3.1e-15 56.3 0.0 4.3e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) OTT_1508_deam PF14441.6 PSC67204.1 - 0.13 12.3 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 OTT_1508-like deaminase P-II PF00543.22 PSC67205.1 - 7.5e-28 97.1 0.9 1.1e-27 96.6 0.9 1.2 1 0 0 1 1 1 1 Nitrogen regulatory protein P-II DUF1929 PF09118.11 PSC67206.1 - 6.8e-15 55.1 0.0 1.4e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.11 PSC67206.1 - 2.5e-07 30.2 0.0 1e-06 28.1 0.0 2.0 2 1 0 2 2 2 1 Glyoxal oxidase N-terminus Kelch_6 PF13964.6 PSC67206.1 - 9e-07 29.0 2.9 1.4 9.4 0.1 5.5 4 1 1 5 5 5 3 Kelch motif Kelch_4 PF13418.6 PSC67206.1 - 0.0028 17.6 3.7 3.9 7.6 0.0 4.6 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_3 PF13415.6 PSC67206.1 - 0.029 14.7 0.4 2.1 8.7 0.1 3.4 3 0 0 3 3 3 0 Galactose oxidase, central domain Kelch_1 PF01344.25 PSC67206.1 - 0.04 13.5 1.8 21 4.8 0.0 4.2 4 1 0 4 4 4 0 Kelch motif Retrotran_gag_2 PF14223.6 PSC67207.1 - 7.9e-22 77.4 0.0 9.1e-22 77.2 0.0 1.0 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type PTH2 PF01981.16 PSC67208.1 - 1e-15 58.0 0.0 1.3e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 ABC1 PF03109.16 PSC67209.1 - 2.9e-32 111.3 0.0 5.4e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 PSC67209.1 - 7.6e-07 29.3 2.5 7.6e-07 29.3 2.5 3.1 2 2 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 PSC67209.1 - 0.00073 19.0 0.0 0.045 13.1 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain WaaY PF06176.11 PSC67209.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) PI3_PI4_kinase PF00454.27 PSC67209.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Phosphatidylinositol 3- and 4-kinase Nucleoporin_N PF08801.11 PSC67210.1 - 1.4e-67 228.3 0.0 2e-67 227.9 0.0 1.2 1 0 0 1 1 1 1 Nup133 N terminal like DUF1929 PF09118.11 PSC67211.1 - 1.4e-12 47.7 0.0 3.2e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.11 PSC67211.1 - 1.9e-12 46.9 0.1 8.5e-11 41.5 0.0 3.2 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus Kelch_6 PF13964.6 PSC67211.1 - 2.2e-08 34.1 7.6 0.045 14.1 0.0 7.0 8 1 1 9 9 9 2 Kelch motif Kelch_2 PF07646.15 PSC67211.1 - 1.3e-06 28.1 1.3 0.63 10.1 0.1 5.9 6 0 0 6 6 6 1 Kelch motif Kelch_4 PF13418.6 PSC67211.1 - 0.00094 19.1 0.8 38 4.4 0.0 5.7 6 0 0 6 6 6 0 Galactose oxidase, central domain Kelch_1 PF01344.25 PSC67211.1 - 0.0049 16.4 0.0 5.5 6.7 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 PSC67211.1 - 0.18 11.8 6.2 21 5.2 0.1 4.6 5 0 0 5 5 5 0 Kelch motif DUF1929 PF09118.11 PSC67212.1 - 1.3e-12 47.8 0.0 3e-12 46.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.11 PSC67212.1 - 1.3e-12 47.4 0.1 7.8e-11 41.6 0.0 3.5 4 1 0 4 4 4 1 Glyoxal oxidase N-terminus Kelch_6 PF13964.6 PSC67212.1 - 3.9e-09 36.5 5.1 0.042 14.1 0.0 6.7 7 1 1 8 8 8 2 Kelch motif Kelch_2 PF07646.15 PSC67212.1 - 1.1e-06 28.3 1.3 0.59 10.2 0.1 5.9 6 0 0 6 6 6 1 Kelch motif Kelch_4 PF13418.6 PSC67212.1 - 0.00078 19.4 0.8 36 4.5 0.0 5.7 6 0 0 6 6 6 0 Galactose oxidase, central domain Kelch_1 PF01344.25 PSC67212.1 - 0.0045 16.5 0.0 5.2 6.7 0.0 3.6 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 PSC67212.1 - 0.051 13.6 1.8 20 5.3 0.1 3.9 4 0 0 4 4 4 0 Kelch motif Vps8 PF12816.7 PSC67213.1 - 5.1e-36 124.0 0.0 1.2e-35 122.8 0.0 1.5 2 0 0 2 2 2 1 Golgi CORVET complex core vacuolar protein 8 Spt20 PF12090.8 PSC67213.1 - 2 8.0 7.0 3 7.4 7.0 1.2 1 0 0 1 1 1 0 Spt20 family mTERF PF02536.14 PSC67214.1 - 0.27 10.1 0.0 0.35 9.7 0.0 1.2 1 0 0 1 1 1 0 mTERF Mis12 PF05859.12 PSC67215.1 - 9e-12 45.2 0.0 9e-12 45.2 0.0 2.9 3 1 0 3 3 3 1 Mis12 protein Sulfotransfer_1 PF00685.27 PSC67215.1 - 3.8e-07 29.9 0.0 7.5e-07 28.9 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PSC67215.1 - 3.2e-05 24.4 14.5 0.0002 21.8 0.0 4.5 5 1 0 5 5 5 2 Sulfotransferase family ThiF PF00899.21 PSC67218.1 - 3.2e-102 341.1 0.0 4.5e-68 229.2 0.0 2.4 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 PSC67218.1 - 7.6e-77 258.6 0.0 1.1e-76 258.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 PSC67218.1 - 5.2e-24 84.8 0.0 9.9e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 PSC67218.1 - 5.7e-23 80.9 0.2 1.2e-22 79.9 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 PSC67218.1 - 9.1e-23 80.2 0.4 7.5e-22 77.3 0.1 2.4 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle Shikimate_DH PF01488.20 PSC67218.1 - 0.00013 22.0 0.5 0.071 13.2 0.1 2.5 2 0 0 2 2 2 2 Shikimate / quinate 5-dehydrogenase Pyr_redox_2 PF07992.14 PSC67218.1 - 0.0025 17.1 0.3 2.2 7.4 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 PSC67218.1 - 0.02 14.2 0.1 3.2 7.1 0.0 2.4 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AA_permease_2 PF13520.6 PSC67221.1 - 4.7e-38 131.1 35.2 5.8e-38 130.8 35.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 PSC67221.1 - 5e-15 55.0 26.5 6.4e-14 51.4 26.6 2.2 1 1 0 1 1 1 1 Amino acid permease AA_permease_2 PF13520.6 PSC67222.1 - 4.7e-38 131.1 35.2 5.8e-38 130.8 35.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 PSC67222.1 - 5e-15 55.0 26.5 6.4e-14 51.4 26.6 2.2 1 1 0 1 1 1 1 Amino acid permease DUF3605 PF12239.8 PSC67228.1 - 0.00011 22.5 0.0 0.00066 20.0 0.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) DUF3605 PF12239.8 PSC67229.1 - 1.4e-11 44.9 0.0 7e-05 23.2 0.1 2.8 1 1 1 2 2 2 2 Protein of unknown function (DUF3605) PUF PF00806.19 PSC67230.1 - 1.3e-13 49.8 0.0 0.13 12.0 0.0 7.0 7 0 0 7 7 7 5 Pumilio-family RNA binding repeat CDP-OH_P_transf PF01066.21 PSC67231.1 - 0.016 16.0 0.3 0.02 15.7 0.3 1.2 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase TIM21 PF08294.11 PSC67232.1 - 3e-21 75.8 0.0 7.2e-21 74.6 0.0 1.5 2 0 0 2 2 2 1 TIM21 DUF2561 PF10812.8 PSC67232.1 - 0.0032 17.5 1.0 0.0049 16.9 1.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2561) Coa1 PF08695.10 PSC67232.1 - 0.026 14.3 0.0 0.08 12.7 0.0 1.7 1 1 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 TIM21 PF08294.11 PSC67233.1 - 3.8e-21 75.5 0.0 7.2e-21 74.6 0.0 1.4 2 0 0 2 2 2 1 TIM21 Coa1 PF08695.10 PSC67233.1 - 0.026 14.3 0.0 0.08 12.7 0.0 1.7 1 1 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 DUF2561 PF10812.8 PSC67233.1 - 0.043 13.9 0.9 0.065 13.3 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) FH2 PF02181.23 PSC67234.1 - 3.3e-84 283.2 0.5 4.6e-84 282.7 0.5 1.2 1 0 0 1 1 1 1 Formin Homology 2 Domain Ku_PK_bind PF08785.11 PSC67234.1 - 0.082 13.1 0.1 0.39 10.9 0.0 2.1 2 0 0 2 2 2 0 Ku C terminal domain like DUF1654 PF07867.11 PSC67234.1 - 1.4 8.7 3.6 2.7 7.8 2.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) Mac PF12464.8 PSC67235.1 - 6.8e-16 58.2 0.7 9.8e-16 57.7 0.7 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 PSC67235.1 - 2.5e-14 52.4 7.7 1.1e-11 43.9 2.7 2.8 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 PSC67235.1 - 3.3e-14 52.3 3.1 4.5e-10 39.1 1.9 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase VHL PF01847.16 PSC67236.1 - 5.1e-07 29.5 0.0 8.1e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 VHL beta domain DUF4766 PF15973.5 PSC67236.1 - 0.18 12.4 0.3 0.18 12.4 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4766) Glyco_transf_8 PF01501.20 PSC67237.1 - 2.3e-07 30.6 0.0 7e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase family 8 TPR_11 PF13414.6 PSC67238.1 - 0.00098 18.8 0.0 0.0068 16.1 0.0 2.6 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.17 PSC67238.1 - 0.0053 16.8 0.2 0.0053 16.8 0.2 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat CS PF04969.16 PSC67238.1 - 0.0057 17.7 0.0 0.011 16.8 0.0 1.4 1 0 0 1 1 1 1 CS domain GP38 PF05268.11 PSC67238.1 - 0.02 14.5 5.4 0.11 12.2 0.6 2.3 2 0 0 2 2 2 0 Phage tail fibre adhesin Gp38 TFIIA PF03153.13 PSC67238.1 - 1.4 8.8 17.3 0.21 11.5 5.4 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TPR_16 PF13432.6 PSC67238.1 - 3.2 8.5 40.4 0.044 14.4 12.1 5.8 3 2 1 4 4 4 0 Tetratricopeptide repeat Cyt-b5 PF00173.28 PSC67239.1 - 8.5e-10 38.6 0.0 1.4e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Spt20 PF12090.8 PSC67239.1 - 0.14 11.8 14.1 0.21 11.2 14.1 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 PSC67239.1 - 0.21 11.6 11.2 0.29 11.1 11.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 PSC67239.1 - 0.92 8.4 8.7 1.2 8.0 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Androgen_recep PF02166.16 PSC67239.1 - 1.8 7.4 27.3 0.032 13.1 20.3 1.5 2 0 0 2 2 2 0 Androgen receptor A_deaminase PF00962.22 PSC67240.1 - 9.1e-123 409.8 0.5 1.2e-122 409.4 0.5 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase PF00962.22 PSC67241.1 - 9e-123 409.8 0.5 1.2e-122 409.4 0.5 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase B12D PF06522.11 PSC67242.1 - 6.9e-06 25.8 0.1 9.2e-06 25.4 0.1 1.4 1 1 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit Alpha-L-AF_C PF06964.12 PSC67243.1 - 3.7e-14 53.2 1.7 1.7e-06 28.2 0.1 2.3 1 1 1 2 2 2 2 Alpha-L-arabinofuranosidase C-terminal domain CBM_4_9 PF02018.17 PSC67243.1 - 7.2e-05 23.1 0.0 0.00018 21.8 0.0 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain Sec62 PF03839.16 PSC67244.1 - 2.2e-17 63.3 0.1 3.7e-17 62.6 0.0 1.4 2 0 0 2 2 2 1 Translocation protein Sec62 Iso_dh PF00180.20 PSC67246.1 - 2.5e-68 230.8 0.0 3e-39 135.2 0.0 2.0 2 0 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase Peptidase_S8 PF00082.22 PSC67247.1 - 3.4e-35 121.8 0.0 3.4e-35 121.8 0.0 1.8 2 0 0 2 2 2 1 Subtilase family TFIIA PF03153.13 PSC67247.1 - 0.42 10.5 42.6 0.059 13.4 38.1 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF778 PF05608.12 PSC67247.1 - 1.4 9.3 8.3 1.2e+02 3.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF778) Ank_3 PF13606.6 PSC67248.1 - 0.0013 19.0 0.6 2.6 8.9 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 PSC67248.1 - 0.12 13.0 0.1 1.2 9.8 0.0 2.5 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) zf-HIT PF04438.16 PSC67253.1 - 7.9e-09 35.2 11.1 1.2e-08 34.7 11.1 1.3 1 0 0 1 1 1 1 HIT zinc finger ABC2_membrane PF01061.24 PSC67254.1 - 1.4e-34 119.3 14.6 1.9e-34 118.9 14.6 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PSC67254.1 - 1.6e-24 87.0 0.0 2.9e-24 86.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 PSC67254.1 - 6.4e-06 26.2 0.1 2e-05 24.6 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase SMC_N PF02463.19 PSC67254.1 - 8.2e-06 25.4 0.0 0.0096 15.4 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PSC67254.1 - 9.9e-06 26.0 0.0 2.1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 PSC67254.1 - 1.8e-05 24.7 0.1 0.2 11.4 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PSC67254.1 - 0.00047 19.8 0.1 0.00094 18.9 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 PSC67254.1 - 0.0013 19.2 0.0 0.002 18.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PSC67254.1 - 0.0068 16.7 0.1 0.016 15.5 0.1 1.7 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.23 PSC67254.1 - 0.0072 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_27 PF13514.6 PSC67254.1 - 0.022 14.3 0.0 0.038 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 PSC67254.1 - 0.023 14.3 0.2 0.07 12.7 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PSC67254.1 - 0.023 14.9 0.0 0.051 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PSC67254.1 - 0.03 14.9 0.0 0.32 11.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 PSC67254.1 - 0.11 12.2 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 PSC67254.1 - 0.16 11.6 0.0 0.27 11.0 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase Peptidase_C1 PF00112.23 PSC67255.1 - 4.5e-40 138.1 0.0 8.1e-40 137.2 0.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PSC67255.1 - 1.7e-08 34.8 0.3 3e-08 34.0 0.3 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PSC67255.1 - 0.27 10.0 0.0 45 2.6 0.0 2.8 3 0 0 3 3 3 0 Peptidase C1-like family Form_Nir_trans PF01226.17 PSC67256.1 - 3.7e-57 193.4 23.7 4.4e-57 193.1 23.7 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter PsiB PF06290.11 PSC67256.1 - 0.054 13.0 0.0 0.091 12.2 0.0 1.3 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) Hydrolase_6 PF13344.6 PSC67257.1 - 4.9e-13 49.1 0.0 1.2e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Cu-oxidase_2 PF07731.14 PSC67257.1 - 9.3e-12 44.9 0.1 2.1e-11 43.7 0.1 1.5 1 0 0 1 1 1 1 Multicopper oxidase Hydrolase_like PF13242.6 PSC67257.1 - 3.3e-09 36.7 0.0 8.4e-09 35.4 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Cu-oxidase_3 PF07732.15 PSC67257.1 - 1.8e-05 24.8 0.4 0.31 11.1 0.0 2.7 2 1 0 2 2 2 2 Multicopper oxidase ABC_tran PF00005.27 PSC67258.1 - 1.4e-46 158.4 0.0 4.4e-26 92.0 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC_membrane PF00664.23 PSC67258.1 - 9.9e-43 146.7 18.7 3.2e-23 82.8 7.3 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region AAA_21 PF13304.6 PSC67258.1 - 3.9e-08 33.5 0.1 0.012 15.5 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PSC67258.1 - 1.4e-07 31.2 5.2 0.027 13.9 0.1 4.2 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 PSC67258.1 - 5.6e-07 29.6 0.7 0.022 14.8 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 PSC67258.1 - 6.1e-06 25.9 0.3 0.1 12.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 PSC67258.1 - 4.4e-05 23.9 0.1 0.33 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 PSC67258.1 - 6.5e-05 22.9 1.2 0.019 14.9 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 PSC67258.1 - 0.00029 21.4 0.7 1.7 9.1 0.0 3.0 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.6 PSC67258.1 - 0.00088 19.6 1.4 1.9 8.8 0.1 3.4 3 1 0 3 3 2 2 AAA domain Dynamin_N PF00350.23 PSC67258.1 - 0.00098 19.2 7.1 0.012 15.7 0.2 2.8 3 0 0 3 3 3 2 Dynamin family FtsK_SpoIIIE PF01580.18 PSC67258.1 - 0.0025 17.2 0.1 0.4 10.0 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_15 PF13175.6 PSC67258.1 - 0.003 17.3 2.0 0.35 10.5 0.0 2.5 3 0 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 PSC67258.1 - 0.0035 17.1 0.6 7.6 6.2 0.0 3.8 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_7 PF12775.7 PSC67258.1 - 0.0055 16.2 0.3 1.9 8.0 0.0 2.6 3 0 0 3 3 3 1 P-loop containing dynein motor region AAA_30 PF13604.6 PSC67258.1 - 0.0072 16.1 0.0 5.1 6.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain NTPase_1 PF03266.15 PSC67258.1 - 0.0082 16.1 0.6 0.2 11.6 0.1 2.5 2 0 0 2 2 2 1 NTPase NACHT PF05729.12 PSC67258.1 - 0.0088 16.0 0.1 3.2 7.6 0.0 2.9 2 0 0 2 2 2 1 NACHT domain cobW PF02492.19 PSC67258.1 - 0.019 14.6 1.9 1.7 8.2 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 PSC67258.1 - 0.02 15.1 0.0 5 7.4 0.0 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit NB-ARC PF00931.22 PSC67258.1 - 0.031 13.5 1.0 4.8 6.3 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.6 PSC67258.1 - 0.032 13.8 0.4 3.7 7.1 0.1 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 PSC67258.1 - 0.033 14.3 3.1 0.52 10.4 0.4 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain T2SSE PF00437.20 PSC67258.1 - 0.044 12.8 0.1 0.95 8.5 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 PSC67258.1 - 0.056 13.7 0.2 18 5.6 0.1 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Zeta_toxin PF06414.12 PSC67258.1 - 0.081 12.2 0.5 4.4 6.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin ATP_bind_1 PF03029.17 PSC67258.1 - 0.081 12.7 0.4 2.4 7.8 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 PSC67258.1 - 0.15 12.6 0.1 3.5 8.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 PSC67258.1 - 0.24 11.4 1.0 2 8.5 0.0 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 PSC67258.1 - 0.27 10.4 0.5 10 5.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Aa_trans PF01490.18 PSC67259.1 - 9.1e-30 103.7 0.7 1.4e-29 103.1 0.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein 4F5 PF04419.14 PSC67260.1 - 2e-10 41.3 4.5 2e-10 41.3 4.5 3.6 3 0 0 3 3 3 1 4F5 protein family bZIP_1 PF00170.21 PSC67260.1 - 6.5e-09 35.8 12.6 6.5e-09 35.8 12.6 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 PSC67260.1 - 0.0013 18.8 16.0 0.0025 17.8 11.0 2.6 1 1 1 2 2 2 2 Basic region leucine zipper Phlebovirus_NSM PF07246.11 PSC67260.1 - 0.3 10.4 1.4 0.48 9.8 1.4 1.2 1 0 0 1 1 1 0 Phlebovirus nonstructural protein NS-M bZIP_Maf PF03131.17 PSC67260.1 - 4 8.0 12.4 11 6.6 12.4 1.6 1 0 0 1 1 1 0 bZIP Maf transcription factor LUC7 PF03194.15 PSC67262.1 - 1.7e-49 168.8 4.3 2.6e-49 168.2 4.3 1.3 1 0 0 1 1 1 1 LUC7 N_terminus Complex1_LYR PF05347.15 PSC67263.1 - 0.00058 19.8 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) KDZ PF18758.1 PSC67265.1 - 1.6e-26 93.3 0.1 2.6e-26 92.6 0.1 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CxC3 PF18804.1 PSC67265.1 - 0.0012 18.7 1.6 0.0037 17.1 1.6 1.8 1 0 0 1 1 1 1 CxC3 like cysteine cluster associated with KDZ transposases DUF2269 PF10027.9 PSC67265.1 - 0.1 12.7 0.2 0.31 11.1 0.2 1.8 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) THOC7 PF05615.13 PSC67265.1 - 0.11 12.8 3.1 13 6.1 0.1 2.8 2 0 0 2 2 2 0 Tho complex subunit 7 Tnp_DNA_bind PF14706.6 PSC67265.1 - 7.9 6.4 10.7 20 5.1 0.0 4.1 4 0 0 4 4 4 0 Transposase DNA-binding LTXXQ PF07813.12 PSC67266.1 - 0.014 16.1 0.3 0.014 16.1 0.3 3.3 4 0 0 4 4 4 0 LTXXQ motif family protein REGB_T4 PF10715.9 PSC67266.1 - 0.055 13.7 0.0 0.098 12.9 0.0 1.4 1 0 0 1 1 1 0 T4-page Endoribonuclease RegB PUF PF00806.19 PSC67267.1 - 0.04 13.6 0.0 20 5.1 0.0 3.4 3 0 0 3 3 3 0 Pumilio-family RNA binding repeat DnaB_bind PF10410.9 PSC67267.1 - 0.042 14.0 0.4 19 5.5 0.0 3.3 3 0 0 3 3 3 0 DnaB-helicase binding domain of primase DUF2526 PF10735.9 PSC67267.1 - 0.41 10.8 0.0 0.41 10.8 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2526) TPT PF03151.16 PSC67268.1 - 5.2e-07 29.3 1.6 5.5e-07 29.2 1.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PSC67268.1 - 0.00021 21.4 8.9 0.0017 18.5 1.2 2.0 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 PSC67268.1 - 0.00044 19.6 0.5 0.00052 19.3 0.5 1.2 1 0 0 1 1 1 1 UAA transporter family ArsD PF06953.11 PSC67268.1 - 0.19 12.1 0.0 0.32 11.3 0.0 1.4 1 0 0 1 1 1 0 Arsenical resistance operon trans-acting repressor ArsD Exostosin PF03016.15 PSC67269.1 - 2.6e-06 26.9 0.1 2.6e-06 26.9 0.1 1.0 1 0 0 1 1 1 1 Exostosin family EGF_2 PF07974.13 PSC67270.1 - 0.028 14.8 10.3 0.028 14.8 10.3 3.9 3 2 1 4 4 4 0 EGF-like domain Exostosin PF03016.15 PSC67271.1 - 1.7e-11 43.9 0.0 2e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Exostosin family ARID PF01388.21 PSC67273.1 - 0.042 14.5 0.0 1.1 10.0 0.0 2.4 2 0 0 2 2 2 0 ARID/BRIGHT DNA binding domain zf-LYAR PF08790.11 PSC67274.1 - 7e-13 48.2 5.4 7e-13 48.2 5.4 2.5 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger zf-met PF12874.7 PSC67274.1 - 1.5e-05 25.2 0.2 1.5e-05 25.2 0.2 2.3 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 PSC67274.1 - 0.00033 20.9 2.4 0.15 12.4 0.0 2.3 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 PSC67274.1 - 0.075 13.3 4.2 0.13 12.5 0.0 3.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf_C2H2_ZHX PF18387.1 PSC67274.1 - 0.24 11.1 6.5 9.6 5.9 0.0 3.4 2 1 1 3 3 3 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_4 PF13894.6 PSC67274.1 - 2.3 9.3 13.1 1.3 10.0 0.2 3.8 3 1 1 4 4 4 0 C2H2-type zinc finger zf_UBZ PF18439.1 PSC67274.1 - 5.6 6.6 9.4 7.7 6.2 1.2 2.8 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger DUF4551 PF15087.6 PSC67274.1 - 8 5.2 10.2 9.9 4.9 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) KDZ PF18758.1 PSC67275.1 - 2e-05 24.3 0.0 0.12 11.9 0.0 2.3 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase DUF4407 PF14362.6 PSC67275.1 - 0.043 13.2 1.9 0.043 13.2 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) RRM_1 PF00076.22 PSC67276.1 - 1.6e-21 75.9 0.1 2.8e-21 75.1 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 PSC67276.1 - 2.4e-13 50.5 9.1 2.4e-13 50.5 9.1 3.7 3 2 0 3 3 3 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_8 PF11835.8 PSC67276.1 - 0.019 15.1 0.0 0.034 14.3 0.0 1.3 1 0 0 1 1 1 0 RRM-like domain RRM_7 PF16367.5 PSC67276.1 - 0.06 13.5 0.0 0.16 12.1 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif EIF4E-T PF10477.9 PSC67276.1 - 2.8 6.7 28.6 3.1 6.5 28.6 1.2 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E LSM PF01423.22 PSC67278.1 - 1.2e-18 66.5 0.4 1.4e-18 66.3 0.4 1.1 1 0 0 1 1 1 1 LSM domain KDZ PF18758.1 PSC67279.1 - 2.5e-05 24.0 0.0 0.17 11.5 0.0 2.3 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase DUF563 PF04577.14 PSC67281.1 - 4.7e-10 40.0 0.0 7.1e-10 39.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Myotoxins PF00819.17 PSC67281.1 - 0.37 11.1 1.8 0.53 10.6 0.1 2.1 2 0 0 2 2 2 0 Myotoxin, crotamine RRM_1 PF00076.22 PSC67282.1 - 5e-84 276.1 0.9 1.3e-21 76.2 0.1 4.2 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 PSC67282.1 - 3.1e-28 97.7 0.3 1.6e-26 92.3 0.4 2.5 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 PSC67282.1 - 1.4e-12 47.3 0.0 0.00092 18.8 0.0 4.2 1 1 3 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PSC67282.1 - 1.2e-07 31.5 0.0 3.9e-05 23.4 0.0 2.8 2 0 0 2 2 2 1 Occluded RNA-recognition motif RRM_7 PF16367.5 PSC67282.1 - 4.1e-07 30.0 0.1 1.4 9.1 0.0 4.8 4 2 0 4 4 4 2 RNA recognition motif RRM_3 PF08777.11 PSC67282.1 - 0.00051 20.0 1.5 3.3 7.8 0.2 3.9 4 0 0 4 4 4 2 RNA binding motif OB_RNB PF08206.11 PSC67282.1 - 0.0023 17.6 1.6 3 7.6 0.0 3.5 3 0 0 3 3 3 1 Ribonuclease B OB domain Nup35_RRM_2 PF14605.6 PSC67282.1 - 0.0058 16.6 0.1 1.5 8.9 0.0 3.6 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif IF2_N PF04760.15 PSC67282.1 - 0.016 15.0 0.0 0.74 9.7 0.0 3.1 3 0 0 3 3 3 0 Translation initiation factor IF-2, N-terminal region YflT PF11181.8 PSC67282.1 - 0.039 14.5 0.2 15 6.2 0.1 2.6 2 0 0 2 2 2 0 Heat induced stress protein YflT Cas_Cas2CT1978 PF09707.10 PSC67282.1 - 0.13 12.3 0.1 14 5.9 0.0 3.7 4 0 0 4 4 4 0 CRISPR-associated protein (Cas_Cas2CT1978) Lipase_GDSL_lke PF16255.5 PSC67283.1 - 0.054 12.8 0.0 0.098 12.0 0.0 1.3 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Glyco_transf_34 PF05637.12 PSC67283.1 - 0.13 12.0 0.2 0.24 11.1 0.2 1.4 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family CRAL_TRIO PF00650.20 PSC67286.1 - 3.9e-30 104.7 0.0 5.6e-30 104.2 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PSC67286.1 - 0.0039 17.4 0.2 0.011 15.9 0.2 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain Glyco_transf_34 PF05637.12 PSC67287.1 - 0.0038 17.0 0.0 0.0065 16.2 0.0 1.3 1 0 0 1 1 1 1 galactosyl transferase GMA12/MNN10 family CRAL_TRIO PF00650.20 PSC67288.1 - 1.5e-06 28.0 0.0 6e-05 22.8 0.0 2.1 1 1 1 2 2 2 2 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PSC67288.1 - 0.02 15.1 0.7 0.036 14.2 0.7 1.4 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain EamA PF00892.20 PSC67289.1 - 0.00077 19.6 9.7 0.00089 19.4 9.7 1.1 1 0 0 1 1 1 1 EamA-like transporter family DUF2070 PF09843.9 PSC67289.1 - 0.007 14.7 1.8 0.007 14.7 1.8 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) LapA_dom PF06305.11 PSC67289.1 - 0.055 13.3 5.0 0.5 10.2 1.0 2.5 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain LTXXQ PF07813.12 PSC67290.1 - 0.0011 19.7 0.3 0.0018 19.0 0.3 1.3 1 0 0 1 1 1 1 LTXXQ motif family protein LEAP-2 PF07359.11 PSC67290.1 - 0.17 11.7 0.0 0.44 10.4 0.0 1.6 1 0 0 1 1 1 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) PAPS_reduct PF01507.19 PSC67291.1 - 4e-39 134.4 0.0 6.6e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoadenosine phosphosulfate reductase family Thioredoxin PF00085.20 PSC67291.1 - 2.1e-14 53.4 0.0 3.6e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 PSC67291.1 - 2.9e-05 23.6 0.0 4.4e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 PSC67291.1 - 0.0028 18.1 0.1 0.019 15.4 0.1 2.2 1 1 0 1 1 1 1 Thioredoxin-like domain TraF PF13728.6 PSC67291.1 - 0.009 15.9 0.0 0.026 14.4 0.0 1.8 2 0 0 2 2 2 1 F plasmid transfer operon protein Prefoldin_2 PF01920.20 PSC67292.1 - 1.3e-19 70.1 12.8 5.5e-19 68.1 12.8 1.8 1 1 0 1 1 1 1 Prefoldin subunit Snapin_Pallidin PF14712.6 PSC67292.1 - 0.002 18.5 2.0 0.002 18.5 2.0 2.3 2 1 0 2 2 2 1 Snapin/Pallidin RasGAP_C PF03836.15 PSC67292.1 - 0.021 14.9 4.3 0.81 9.8 0.1 2.1 2 0 0 2 2 2 0 RasGAP C-terminus DUF1732 PF08340.11 PSC67292.1 - 0.038 14.0 0.2 0.038 14.0 0.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF1732) TMF_TATA_bd PF12325.8 PSC67292.1 - 0.052 13.8 9.8 0.21 11.8 0.4 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF4404 PF14357.6 PSC67292.1 - 0.054 14.1 1.6 0.054 14.1 1.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) XhlA PF10779.9 PSC67292.1 - 0.12 12.6 0.4 0.12 12.6 0.4 1.8 2 0 0 2 2 2 0 Haemolysin XhlA Rx_N PF18052.1 PSC67292.1 - 0.13 12.5 0.2 0.13 12.5 0.2 3.0 2 1 1 3 3 3 0 Rx N-terminal domain Occludin_ELL PF07303.13 PSC67292.1 - 0.17 12.6 7.2 4.3 8.1 0.4 2.1 2 0 0 2 2 2 0 Occludin homology domain CENP-Q PF13094.6 PSC67292.1 - 0.63 10.2 14.5 17 5.5 14.3 2.0 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Prefoldin PF02996.17 PSC67292.1 - 1.3 8.9 11.6 22 5.0 11.6 2.3 1 1 0 1 1 1 0 Prefoldin subunit NPV_P10 PF05531.12 PSC67292.1 - 2.2 8.8 7.3 0.46 11.0 0.9 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein APG6_N PF17675.1 PSC67292.1 - 2.6 8.6 16.8 74 3.9 16.4 2.1 1 1 0 1 1 1 0 Apg6 coiled-coil region OmpH PF03938.14 PSC67292.1 - 2.8 8.3 22.6 1.8 8.9 7.1 2.1 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) THOC7 PF05615.13 PSC67292.1 - 3.4 7.9 12.4 2.2 8.5 2.2 2.1 2 0 0 2 2 2 0 Tho complex subunit 7 Cluap1 PF10234.9 PSC67292.1 - 5 6.4 13.9 42 3.4 13.9 1.9 1 1 0 1 1 1 0 Clusterin-associated protein-1 DivIC PF04977.15 PSC67292.1 - 9.5 6.1 17.1 7 6.5 3.3 2.5 2 1 0 2 2 2 0 Septum formation initiator Pkinase PF00069.25 PSC67293.1 - 2.1e-53 181.4 0.0 2.8e-53 181.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC67293.1 - 5.5e-18 65.2 0.0 9.9e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PSC67293.1 - 0.00072 19.5 0.0 0.00072 19.5 0.0 4.9 2 2 2 4 4 4 2 Phosphotransferase enzyme family Kdo PF06293.14 PSC67293.1 - 0.026 13.9 0.0 0.051 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PSC67293.1 - 0.031 13.9 0.4 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.22 PSC67293.1 - 0.05 13.2 0.0 0.097 12.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family PRP38 PF03371.15 PSC67294.1 - 1.1e-45 155.6 0.0 1.7e-45 155.0 0.0 1.1 1 0 0 1 1 1 1 PRP38 family Methyltransf_24 PF13578.6 PSC67295.1 - 1.6e-12 48.3 0.0 3.7e-12 47.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain DnaJ PF00226.31 PSC67296.1 - 9.3e-20 70.5 2.8 6.3e-18 64.7 1.7 2.4 2 0 0 2 2 2 2 DnaJ domain Sec63 PF02889.16 PSC67296.1 - 2e-15 56.7 0.0 2.4e-14 53.1 0.0 2.0 1 1 0 1 1 1 1 Sec63 Brl domain Mob1_phocein PF03637.17 PSC67297.1 - 4.7e-70 235.0 0.0 5.5e-70 234.8 0.0 1.0 1 0 0 1 1 1 1 Mob1/phocein family UPF0220 PF05255.11 PSC67298.1 - 9.5e-15 54.5 1.5 2.2e-14 53.4 1.1 1.5 1 1 1 2 2 2 1 Uncharacterised protein family (UPF0220) DUF3611 PF12263.8 PSC67298.1 - 0.016 15.1 0.8 0.016 15.1 0.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) VirB8 PF04335.13 PSC67298.1 - 0.74 9.6 1.9 1 9.1 0.0 1.8 2 0 0 2 2 2 0 VirB8 protein SKG6 PF08693.10 PSC67300.1 - 0.00016 21.0 0.1 0.00036 19.9 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DprA_WH PF17782.1 PSC67300.1 - 0.025 14.7 0.7 0.025 14.7 0.7 3.9 4 1 0 4 4 4 0 DprA winged helix domain DUF2922 PF11148.8 PSC67300.1 - 0.43 10.3 2.8 0.37 10.5 1.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2922) Neisseria_TspB PF05616.13 PSC67300.1 - 0.69 8.3 11.6 1.4 7.3 11.6 1.4 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein MSA-2c PF12238.8 PSC67300.1 - 1.3 9.0 11.0 2.3 8.2 11.0 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c F-box-like PF12937.7 PSC67301.1 - 5.1e-08 32.7 0.2 2.3e-07 30.6 0.1 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PSC67301.1 - 0.0078 16.1 0.0 0.017 15.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain SKG6 PF08693.10 PSC67301.1 - 0.17 11.3 0.5 0.39 10.2 0.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3877 PF12993.7 PSC67301.1 - 0.79 9.6 2.4 1.4 8.7 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) DUF3683 PF12447.8 PSC67301.1 - 2.5 8.2 6.3 8 6.6 6.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3683) PSP PF04046.16 PSC67302.1 - 1.8e-15 56.5 1.7 5.2e-15 55.0 1.7 1.8 1 0 0 1 1 1 1 PSP zf-CCHC PF00098.23 PSC67302.1 - 0.00082 19.4 3.6 0.0016 18.5 3.6 1.4 1 0 0 1 1 1 1 Zinc knuckle Chalcone_2 PF16035.5 PSC67302.1 - 0.079 12.7 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 Chalcone isomerase like Spore_GerAC PF05504.11 PSC67302.1 - 0.093 13.0 0.1 0.16 12.2 0.1 1.2 1 0 0 1 1 1 0 Spore germination B3/ GerAC like, C-terminal zf-CCHC_4 PF14392.6 PSC67302.1 - 0.13 12.1 1.3 0.27 11.0 1.3 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF3300 PF11737.8 PSC67303.1 - 0.051 13.1 0.0 0.083 12.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) ATP-synt_E PF05680.12 PSC67303.1 - 0.052 13.9 2.7 0.11 12.9 2.7 1.5 1 0 0 1 1 1 0 ATP synthase E chain Pox_A_type_inc PF04508.12 PSC67304.1 - 1.2 9.1 0.0 1.2 9.1 0.0 4.1 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Topoisom_bac PF01131.20 PSC67305.1 - 5.1e-100 335.4 0.0 7.5e-100 334.8 0.0 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 PSC67305.1 - 2.8e-13 50.0 0.0 6.5e-13 48.8 0.0 1.6 1 0 0 1 1 1 1 Toprim domain DUF4817 PF16087.5 PSC67305.1 - 0.033 14.0 0.1 14 5.6 0.0 3.2 3 0 0 3 3 3 0 Helix-turn-helix domain (DUF4817) DZR PF12773.7 PSC67305.1 - 3.2 7.9 6.7 50 4.0 6.7 2.5 1 1 0 1 1 1 0 Double zinc ribbon Acetyltransf_1 PF00583.25 PSC67306.1 - 7.1e-10 39.1 0.1 4e-09 36.7 0.2 2.2 3 0 0 3 3 3 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PSC67306.1 - 2.2e-08 34.1 0.0 5e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PSC67306.1 - 7.1e-07 29.6 0.0 1.8e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 PSC67306.1 - 0.00084 19.1 0.7 0.0024 17.6 0.2 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_4 PF13420.7 PSC67306.1 - 0.0023 18.1 0.0 0.0043 17.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC67306.1 - 0.0024 17.8 0.1 0.006 16.5 0.1 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 PSC67306.1 - 0.005 16.9 0.1 0.01 15.9 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain K_channel_TID PF07941.11 PSC67306.1 - 0.027 14.9 4.0 0.027 14.9 4.0 7.1 5 2 2 7 7 7 0 Potassium channel Kv1.4 tandem inactivation domain PsaL PF02605.15 PSC67307.1 - 1.1e-53 181.0 0.6 2e-53 180.1 0.6 1.4 1 0 0 1 1 1 1 Photosystem I reaction centre subunit XI Acid_PPase PF12689.7 PSC67307.1 - 8.2e-33 113.6 0.1 1.5e-30 106.2 0.1 2.2 1 1 0 1 1 1 1 Acid Phosphatase PQQ_2 PF13360.6 PSC67307.1 - 2.4e-15 56.8 11.7 3.1e-12 46.6 2.1 2.8 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 PSC67307.1 - 0.0062 16.4 2.6 3.7 7.7 0.2 4.2 4 0 0 4 4 4 1 PQQ enzyme repeat PQQ_3 PF13570.6 PSC67307.1 - 0.057 13.9 17.1 0.48 11.0 0.1 6.0 5 0 0 5 5 5 0 PQQ-like domain HAD_2 PF13419.6 PSC67307.1 - 0.19 11.8 0.0 0.43 10.6 0.0 1.4 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase DSPc PF00782.20 PSC67308.1 - 9.7e-13 48.1 0.0 1.4e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Init_tRNA_PT PF04179.12 PSC67308.1 - 0.002 18.4 0.0 0.003 17.8 0.0 1.2 1 0 0 1 1 1 1 Rit1 DUSP-like domain Y_phosphatase PF00102.27 PSC67308.1 - 0.058 12.9 0.0 0.072 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase CDKN3 PF05706.12 PSC67308.1 - 0.16 11.6 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) ABC1 PF03109.16 PSC67309.1 - 2.9e-38 130.7 0.0 5.2e-38 129.9 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 PSC67309.1 - 0.00022 21.2 3.0 0.0023 17.9 0.0 3.2 2 1 1 3 3 3 1 Phosphotransferase enzyme family HCV_NS4a PF01006.20 PSC67309.1 - 1.3 8.8 6.7 3.6 7.4 6.7 1.7 1 0 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a AAA PF00004.29 PSC67310.1 - 2.8e-38 131.3 0.0 4.8e-38 130.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PSC67310.1 - 1.8e-11 43.6 0.0 4.9e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 PSC67310.1 - 3.8e-07 30.0 0.0 8.5e-07 28.9 0.0 1.6 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_5 PF07728.14 PSC67310.1 - 1.1e-06 28.7 0.0 2.2e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 PSC67310.1 - 1.6e-05 25.1 0.0 2.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 PSC67310.1 - 2.2e-05 24.8 0.0 0.00018 21.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 PSC67310.1 - 2.5e-05 24.0 0.0 4.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PSC67310.1 - 0.0015 19.0 4.8 0.0035 17.7 0.2 3.4 3 1 0 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.17 PSC67310.1 - 0.0015 18.3 0.0 0.0029 17.3 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.6 PSC67310.1 - 0.002 17.8 0.4 0.077 12.6 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 PSC67310.1 - 0.0028 17.7 0.0 0.0049 16.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 PSC67310.1 - 0.0043 16.5 0.0 0.76 9.2 0.0 2.3 1 1 1 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 PSC67310.1 - 0.0057 16.1 0.1 0.012 15.1 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 PSC67310.1 - 0.012 14.8 0.0 0.018 14.2 0.0 1.1 1 0 0 1 1 1 0 TIP49 P-loop domain DUF815 PF05673.13 PSC67310.1 - 0.013 14.6 0.0 0.026 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 PSC67310.1 - 0.027 14.3 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 Bacterial dnaA protein NACHT PF05729.12 PSC67310.1 - 0.063 13.2 0.0 0.22 11.4 0.0 1.9 1 1 1 2 2 2 0 NACHT domain RNA_helicase PF00910.22 PSC67310.1 - 0.11 12.9 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 PSC67310.1 - 0.22 11.2 0.0 0.38 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain TFIIA PF03153.13 PSC67311.1 - 1.6 8.7 21.4 0.46 10.4 12.3 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Sulfotransfer_3 PF13469.6 PSC67312.1 - 3.4e-37 128.9 0.7 6.4e-36 124.8 0.1 2.9 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PSC67312.1 - 3.6e-08 33.2 0.0 1.9e-07 30.9 0.0 1.9 1 1 0 1 1 1 1 Sulfotransferase domain Tcf25 PF04910.14 PSC67313.1 - 5.1e-55 187.0 0.0 6.9e-55 186.5 0.0 1.1 1 0 0 1 1 1 1 Transcriptional repressor TCF25 DUF2207 PF09972.9 PSC67314.1 - 3.8 6.2 4.0 16 4.1 0.0 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) DUF2207 PF09972.9 PSC67315.1 - 3.8 6.2 4.0 16 4.1 0.0 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) CCG PF02754.16 PSC67316.1 - 0.19 12.0 0.1 0.19 12.0 0.1 2.1 2 0 0 2 2 2 0 Cysteine-rich domain Ku PF02735.16 PSC67317.1 - 4e-21 75.7 0.0 3.7e-17 62.7 0.0 2.3 1 1 1 2 2 2 2 Ku70/Ku80 beta-barrel domain SAP PF02037.27 PSC67317.1 - 1.4e-09 37.5 0.0 2.6e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 SAP domain Ku_N PF03731.15 PSC67317.1 - 1.3e-08 34.9 0.0 2.3e-07 30.8 0.0 2.2 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 PSC67317.1 - 2.8e-06 27.9 0.5 2.8e-06 27.9 0.5 2.4 2 1 0 2 2 2 1 Ku70/Ku80 C-terminal arm Ish1 PF10281.9 PSC67317.1 - 0.01 16.1 0.2 0.031 14.6 0.0 2.0 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein DUF1295 PF06966.12 PSC67318.1 - 1.2e-51 175.5 0.0 1.4e-51 175.3 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) Steroid_dh PF02544.16 PSC67318.1 - 0.0011 18.9 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 PSC67318.1 - 0.006 17.0 0.1 0.018 15.4 0.1 1.9 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 PSC67318.1 - 0.022 15.2 0.1 0.086 13.3 0.1 2.0 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF5575 PF17738.1 PSC67318.1 - 0.14 11.1 0.3 2 7.4 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5575) Ank_5 PF13857.6 PSC67319.1 - 1.1e-10 41.6 0.1 6.1e-08 32.8 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Chromo PF00385.24 PSC67319.1 - 2.1e-10 40.3 6.5 5.6e-05 23.0 0.1 3.0 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain Ank PF00023.30 PSC67319.1 - 3e-10 40.1 0.1 2.4e-05 24.6 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 PSC67319.1 - 9.9e-10 38.9 0.0 1.8e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PSC67319.1 - 2.9e-07 30.2 0.0 0.043 14.4 0.0 3.3 3 0 0 3 3 2 2 Ankyrin repeat Ank_4 PF13637.6 PSC67319.1 - 7.6e-07 29.6 0.1 2.8e-06 27.8 0.1 2.0 1 1 1 2 2 2 1 Ankyrin repeats (many copies) BUD22 PF09073.10 PSC67319.1 - 0.00026 20.5 7.5 0.00032 20.2 7.5 1.2 1 0 0 1 1 1 1 BUD22 Tudor_3 PF18115.1 PSC67319.1 - 0.0065 16.3 0.2 5.6 6.9 0.0 3.1 3 0 0 3 3 3 1 DNA repair protein Crb2 Tudor domain DUF2052 PF09747.9 PSC67319.1 - 0.26 11.4 11.4 0.57 10.3 11.4 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) SAPS PF04499.15 PSC67319.1 - 0.44 9.3 2.5 0.57 8.9 2.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.14 PSC67319.1 - 1.1 7.5 8.9 1.5 7.1 8.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 PSC67319.1 - 2.5 7.5 12.8 4.2 6.7 12.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Presenilin PF01080.17 PSC67319.1 - 2.9 6.6 5.5 4.4 6.0 5.5 1.2 1 0 0 1 1 1 0 Presenilin Spore_coat_CotO PF14153.6 PSC67319.1 - 6.3 6.7 15.8 11 5.9 15.8 1.3 1 0 0 1 1 1 0 Spore coat protein CotO zf-MYND PF01753.18 PSC67320.1 - 4.3e-18 65.1 47.7 9.3e-10 38.4 13.2 4.4 4 1 0 4 4 4 2 MYND finger Spt5_N PF11942.8 PSC67320.1 - 0.011 16.8 8.0 0.82 10.7 3.4 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Mut7-C PF01927.16 PSC67320.1 - 1.5 8.9 18.3 0.075 13.1 3.5 3.4 3 1 0 3 3 3 0 Mut7-C RNAse domain FAM176 PF14851.6 PSC67320.1 - 5.2 6.7 7.0 3.4 7.3 2.0 2.3 2 0 0 2 2 2 0 FAM176 family zf-MYND PF01753.18 PSC67321.1 - 2.9e-17 62.4 33.5 8.9e-10 38.5 13.2 4.8 5 1 0 5 5 5 2 MYND finger Spt5_N PF11942.8 PSC67321.1 - 0.01 16.8 8.0 0.75 10.8 3.4 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Mut7-C PF01927.16 PSC67321.1 - 1.3 9.1 18.3 0.072 13.2 3.5 3.5 3 1 0 3 3 3 0 Mut7-C RNAse domain Radial_spoke PF04712.12 PSC67321.1 - 4 6.3 8.1 6.6 5.6 3.3 2.2 2 0 0 2 2 2 0 Radial spokehead-like protein FAM176 PF14851.6 PSC67321.1 - 4.4 7.0 7.0 3.3 7.4 2.0 2.4 2 0 0 2 2 2 0 FAM176 family zf-MYND PF01753.18 PSC67322.1 - 2.8e-17 62.5 33.5 8.8e-10 38.5 13.2 4.8 5 1 0 5 5 5 2 MYND finger Spt5_N PF11942.8 PSC67322.1 - 0.01 16.8 8.0 0.74 10.8 3.4 2.6 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Mut7-C PF01927.16 PSC67322.1 - 1.3 9.2 18.3 0.071 13.2 3.5 3.5 3 1 0 3 3 3 0 Mut7-C RNAse domain Radial_spoke PF04712.12 PSC67322.1 - 3.9 6.3 8.1 6.5 5.6 3.3 2.2 2 0 0 2 2 2 0 Radial spokehead-like protein FAM176 PF14851.6 PSC67322.1 - 4.3 7.0 7.0 3.2 7.4 2.0 2.4 2 0 0 2 2 2 0 FAM176 family zf-C6H2 PF15801.5 PSC67322.1 - 9.9 6.6 29.2 1.8 8.9 8.0 3.6 3 0 0 3 3 3 0 zf-MYND-like zinc finger, mRNA-binding Bromodomain PF00439.25 PSC67323.1 - 4.5e-22 77.9 0.0 9.1e-17 60.9 0.0 2.3 2 0 0 2 2 2 2 Bromodomain Vps54_N PF10475.9 PSC67324.1 - 2.5e-50 171.4 0.0 3.3e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 PSC67324.1 - 4e-46 157.7 0.0 6.1e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function C-terminus (DUF2451) Sec8_exocyst PF04048.14 PSC67324.1 - 0.11 12.4 0.5 0.19 11.6 0.5 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain Spc7 PF08317.11 PSC67325.1 - 0.0033 16.3 16.9 0.0033 16.3 16.9 1.6 2 0 0 2 2 2 1 Spc7 kinetochore protein UPF0242 PF06785.11 PSC67325.1 - 0.011 15.9 11.8 0.011 15.9 11.8 2.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0242) N-terminus CTV_P23 PF04808.12 PSC67325.1 - 1.6 8.2 4.7 2.5 7.6 4.7 1.2 1 0 0 1 1 1 0 Citrus tristeza virus (CTV) P23 protein PQQ_2 PF13360.6 PSC67326.1 - 0.0025 17.4 3.4 1.2 8.7 1.0 3.6 2 2 0 2 2 2 2 PQQ-like domain WD40 PF00400.32 PSC67326.1 - 0.029 15.2 3.0 1.3 10.0 0.0 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat G-patch_2 PF12656.7 PSC67327.1 - 5.1e-23 80.9 2.2 8.2e-23 80.3 0.6 2.3 2 0 0 2 2 2 1 G-patch domain KN17_SH3 PF18131.1 PSC67327.1 - 1.3e-06 28.4 0.2 2.9e-06 27.3 0.2 1.6 1 0 0 1 1 1 1 KN17 SH3-like C-terminal domain KOW PF00467.29 PSC67327.1 - 2.1e-05 24.3 2.5 0.029 14.3 0.0 3.2 3 0 0 3 3 3 2 KOW motif G-patch PF01585.23 PSC67327.1 - 0.0014 18.5 1.4 0.0014 18.5 1.4 2.4 3 0 0 3 3 3 1 G-patch domain CCB1 PF12046.8 PSC67328.1 - 1.2e-55 187.4 0.4 1.9e-55 186.8 0.0 1.5 2 0 0 2 2 2 1 Cofactor assembly of complex C subunit B DUF3930 PF13067.6 PSC67328.1 - 0.015 15.5 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3930) Suf PF05843.14 PSC67328.1 - 0.024 14.6 0.5 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) PP2C PF00481.21 PSC67330.1 - 2.6e-30 105.9 0.0 4.4e-28 98.6 0.0 3.0 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PSC67330.1 - 0.00023 21.1 0.4 0.1 12.5 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) DUF3000 PF11452.8 PSC67330.1 - 0.0042 16.6 5.7 0.51 9.8 1.2 3.8 3 1 1 4 4 4 2 Protein of unknown function (DUF3000) PP2C_2 PF13672.6 PSC67330.1 - 1.6 8.3 10.6 0.45 10.1 7.0 1.9 2 0 0 2 2 2 0 Protein phosphatase 2C CCB1 PF12046.8 PSC67331.1 - 2.3e-45 154.0 0.4 4.8e-45 152.9 0.4 1.5 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B DUF3930 PF13067.6 PSC67331.1 - 0.049 13.9 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3930) F-box-like PF12937.7 PSC67331.1 - 0.095 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 F-box-like Sec16 PF12932.7 PSC67333.1 - 3.5e-07 30.8 0.2 1e-06 29.3 0.0 1.9 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region TFIIA PF03153.13 PSC67333.1 - 0.11 12.5 25.4 0.38 10.7 4.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Aminotran_3 PF00202.21 PSC67334.1 - 2.1e-11 43.1 0.1 4.9e-11 41.9 0.1 1.7 1 1 0 1 1 1 1 Aminotransferase class-III KDZ PF18758.1 PSC67335.1 - 5.5e-13 49.0 3.2 6.9e-13 48.7 3.2 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF2269 PF10027.9 PSC67335.1 - 0.0032 17.5 2.8 0.0054 16.8 1.8 1.8 1 1 1 2 2 2 1 Predicted integral membrane protein (DUF2269) Malate_synthase PF01274.22 PSC67336.1 - 4.9e-205 681.7 0.0 6.1e-205 681.4 0.0 1.1 1 0 0 1 1 1 1 Malate synthase YTV PF07639.11 PSC67337.1 - 0.1 12.7 0.2 0.15 12.2 0.2 1.2 1 0 0 1 1 1 0 YTV Nuf2 PF03800.14 PSC67338.1 - 7.6e-41 139.5 0.1 1.7e-40 138.4 0.1 1.6 1 0 0 1 1 1 1 Nuf2 family DHR10 PF18595.1 PSC67338.1 - 4.8e-21 75.0 18.5 4.8e-21 75.0 18.5 4.3 3 1 1 4 4 3 1 Designed helical repeat protein 10 domain Jnk-SapK_ap_N PF09744.9 PSC67338.1 - 0.00066 19.9 39.5 0.01 16.1 11.3 2.3 2 0 0 2 2 2 2 JNK_SAPK-associated protein-1 ADIP PF11559.8 PSC67338.1 - 0.0011 19.1 37.6 0.069 13.2 18.6 2.7 1 1 1 3 3 3 2 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 PSC67338.1 - 0.0037 16.7 47.8 0.0038 16.6 16.2 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) HALZ PF02183.18 PSC67338.1 - 0.0059 16.8 21.4 0.27 11.5 3.4 5.0 4 1 0 4 4 4 2 Homeobox associated leucine zipper BRE1 PF08647.11 PSC67338.1 - 0.011 15.8 35.5 0.034 14.2 6.8 3.7 2 2 1 3 3 3 0 BRE1 E3 ubiquitin ligase DivIC PF04977.15 PSC67338.1 - 0.02 14.7 45.6 0.049 13.4 3.6 5.5 2 2 3 6 6 6 0 Septum formation initiator DUF3584 PF12128.8 PSC67338.1 - 0.024 12.2 40.0 0.06 10.9 10.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3584) KASH_CCD PF14662.6 PSC67338.1 - 0.044 13.6 35.4 0.11 12.3 9.4 3.3 2 1 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH HAUS-augmin3 PF14932.6 PSC67338.1 - 0.044 13.3 44.9 0.12 12.0 14.9 3.1 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 Myosin_tail_1 PF01576.19 PSC67338.1 - 0.13 10.1 48.3 0.17 9.7 10.6 3.0 1 1 2 3 3 3 0 Myosin tail CtIP_N PF10482.9 PSC67338.1 - 0.17 11.9 25.4 0.19 11.8 2.8 3.5 2 2 1 3 3 3 0 Tumour-suppressor protein CtIP N-terminal domain APG6_N PF17675.1 PSC67338.1 - 0.35 11.4 58.6 0.1 13.1 17.8 4.1 1 1 2 4 4 4 0 Apg6 coiled-coil region ZapB PF06005.12 PSC67338.1 - 0.4 11.2 50.7 0.13 12.7 8.4 5.7 2 2 1 3 3 2 0 Cell division protein ZapB HAUS5 PF14817.6 PSC67338.1 - 0.49 9.1 45.6 0.067 11.9 12.4 2.9 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 5 YabA PF06156.13 PSC67338.1 - 0.58 10.8 27.0 3.6 8.3 2.8 4.8 2 2 2 4 4 4 0 Initiation control protein YabA Mod_r PF07200.13 PSC67338.1 - 0.6 10.2 41.2 0.57 10.3 2.5 4.2 2 2 2 4 4 4 0 Modifier of rudimentary (Mod(r)) protein GAS PF13851.6 PSC67338.1 - 0.74 9.1 38.2 0.29 10.5 17.2 3.4 1 1 3 4 4 4 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 PSC67338.1 - 1.4 9.2 40.1 0.69 10.1 7.7 4.3 2 2 1 3 3 3 0 TATA element modulatory factor 1 TATA binding Spectrin PF00435.21 PSC67338.1 - 1.4 9.5 37.7 1.5 9.4 6.3 3.6 2 2 1 3 3 3 0 Spectrin repeat NRBF2 PF08961.10 PSC67338.1 - 1.6 8.3 24.1 0.1 12.2 3.5 3.5 2 2 1 3 3 3 0 Nuclear receptor-binding factor 2, autophagy regulator DUF3450 PF11932.8 PSC67338.1 - 1.7 7.9 48.2 0.071 12.4 12.9 3.7 1 1 2 4 4 4 0 Protein of unknown function (DUF3450) DUF4201 PF13870.6 PSC67338.1 - 1.7 8.3 31.4 6.8 6.4 0.2 4.0 1 1 2 4 4 4 0 Domain of unknown function (DUF4201) SHE3 PF17078.5 PSC67338.1 - 1.8 8.2 23.3 0.68 9.6 2.2 3.1 2 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 BLOC1_2 PF10046.9 PSC67338.1 - 2.5 8.5 27.6 0.69 10.3 4.8 4.3 1 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 MIS13 PF08202.11 PSC67338.1 - 6.1 6.0 16.7 1.1 8.5 7.8 2.1 2 0 0 2 2 2 0 Mis12-Mtw1 protein family ATG16 PF08614.11 PSC67338.1 - 6.2 7.0 53.1 0.31 11.3 17.0 3.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 PSC67338.1 - 8.4 6.9 16.5 0.11 13.0 0.8 4.2 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Peptidase_M11 PF05548.11 PSC67339.1 - 3.7e-25 88.8 3.0 5.3e-25 88.2 3.0 1.3 1 0 0 1 1 1 1 Gametolysin peptidase M11 NT-C2 PF10358.9 PSC67340.1 - 6.3e-11 42.2 0.0 1.3e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins BNIP2 PF12496.8 PSC67340.1 - 0.059 13.8 0.1 0.28 11.6 0.1 2.2 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 HOOK PF05622.12 PSC67340.1 - 1.1 7.4 66.1 0.016 13.4 16.0 4.6 2 2 0 4 4 4 0 HOOK protein Acetyltransf_1 PF00583.25 PSC67341.1 - 5.6e-07 29.8 0.5 3.4e-06 27.3 0.1 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 PSC67341.1 - 3.1e-05 23.9 0.0 5.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 PSC67341.1 - 9.7e-05 22.3 0.1 0.0002 21.3 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PSC67341.1 - 0.00035 20.9 0.1 0.00091 19.6 0.1 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain PilZ_2 PF16823.5 PSC67341.1 - 0.018 15.2 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 Atypical PilZ domain, cyclic di-GMP receptor Auto_anti-p27 PF06677.12 PSC67342.1 - 2.5e-22 78.7 6.2 5.3e-15 55.3 2.4 2.4 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Guanylate_cyc PF00211.20 PSC67342.1 - 5.7e-14 52.2 0.0 4.9e-13 49.1 0.0 2.0 1 1 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain Ion_trans PF00520.31 PSC67342.1 - 0.00069 18.9 1.3 0.0013 18.0 1.3 1.4 1 0 0 1 1 1 1 Ion transport protein DZR PF12773.7 PSC67342.1 - 0.081 13.0 0.4 0.17 11.9 0.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-NADH-PPase PF09297.11 PSC67342.1 - 0.12 12.1 2.4 0.3 10.8 2.4 1.8 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain DUF2593 PF10767.9 PSC67342.1 - 0.14 12.3 0.2 0.31 11.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) DNA_ligase_ZBD PF03119.16 PSC67342.1 - 0.4 10.7 2.6 1 9.5 2.6 1.7 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain Auto_anti-p27 PF06677.12 PSC67343.1 - 1.7e-31 108.1 9.6 1e-15 57.6 2.4 2.2 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) OrfB_Zn_ribbon PF07282.11 PSC67343.1 - 0.0058 16.5 4.7 0.79 9.7 0.6 2.3 2 0 0 2 2 2 2 Putative transposase DNA-binding domain zf-NADH-PPase PF09297.11 PSC67343.1 - 0.0068 16.0 11.3 0.062 13.0 2.4 3.0 2 0 0 2 2 2 2 NADH pyrophosphatase zinc ribbon domain DZR PF12773.7 PSC67343.1 - 0.0086 16.1 9.4 0.034 14.2 0.4 2.8 3 0 0 3 3 3 2 Double zinc ribbon DUF983 PF06170.12 PSC67343.1 - 0.067 13.6 3.2 1 9.8 0.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF983) PHD_3 PF13922.6 PSC67343.1 - 0.075 13.4 0.7 0.075 13.4 0.7 2.9 3 0 0 3 3 3 0 PHD domain of transcriptional enhancer, Asx zf_Rg PF17915.1 PSC67343.1 - 0.13 11.7 5.8 2.2 7.7 0.5 2.4 2 0 0 2 2 2 0 Reverse gyrase zinc finger DNA_ligase_ZBD PF03119.16 PSC67343.1 - 4.8 7.3 17.8 0.21 11.6 2.6 2.9 3 0 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain Methyltransf_11 PF08241.12 PSC67344.1 - 8.4e-15 55.2 0.1 1.1e-13 51.6 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC67344.1 - 6.2e-14 52.5 0.0 5.3e-12 46.3 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC67344.1 - 1.8e-13 50.5 0.0 7.5e-06 25.8 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 PSC67344.1 - 3.7e-11 43.6 0.0 2.7e-10 40.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC67344.1 - 2.3e-09 37.3 0.0 3.6e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 PSC67344.1 - 0.0018 17.8 0.0 0.0051 16.3 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.18 PSC67344.1 - 0.017 14.5 0.0 0.12 11.7 0.0 1.9 1 1 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_32 PF13679.6 PSC67344.1 - 0.069 13.1 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 PSC67344.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Rtf2 PF04641.12 PSC67345.1 - 0.00012 21.6 7.1 0.00013 21.4 7.1 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-CCHC_3 PF13917.6 PSC67345.1 - 0.00014 21.7 0.6 0.00044 20.2 0.6 1.8 1 0 0 1 1 1 1 Zinc knuckle SRP-alpha_N PF04086.13 PSC67345.1 - 0.0017 18.4 13.3 0.0017 18.4 13.3 1.2 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal zf-CCHC_2 PF13696.6 PSC67345.1 - 0.0019 18.0 1.7 0.0028 17.5 1.7 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 PSC67345.1 - 0.0035 17.3 1.7 0.006 16.6 1.7 1.4 1 0 0 1 1 1 1 Zinc knuckle RNA_polI_A34 PF08208.11 PSC67345.1 - 0.075 13.1 28.8 0.11 12.6 28.8 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 EOS1 PF12326.8 PSC67345.1 - 0.084 12.8 1.6 0.089 12.7 1.6 1.3 1 0 0 1 1 1 0 N-glycosylation protein YL1 PF05764.13 PSC67345.1 - 0.092 12.9 25.0 0.15 12.2 25.0 1.2 1 0 0 1 1 1 0 YL1 nuclear protein GAGA_bind PF06217.12 PSC67345.1 - 0.094 13.0 9.5 0.13 12.6 9.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.12 PSC67345.1 - 0.32 10.8 14.4 0.42 10.4 14.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 PSC67345.1 - 0.5 10.4 3.7 0.51 10.4 3.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RNA_pol_Rpc4 PF05132.14 PSC67345.1 - 0.88 10.0 14.4 1.3 9.4 14.4 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 VIR_N PF15912.5 PSC67345.1 - 2.8 7.5 10.4 3.7 7.1 10.4 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal NARP1 PF12569.8 PSC67345.1 - 4.4 6.1 21.9 6.4 5.6 21.9 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GOLD_2 PF13897.6 PSC67345.1 - 6.3 7.3 6.4 10 6.6 6.4 1.3 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF4603 PF15376.6 PSC67345.1 - 9.6 3.4 21.8 11 3.2 21.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) TFIIF_alpha PF05793.12 PSC67345.1 - 9.7 4.6 31.6 12 4.4 31.6 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) RRM_1 PF00076.22 PSC67346.1 - 2.4e-24 85.0 0.0 9.7e-13 47.8 0.0 2.9 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OCRE PF17780.1 PSC67346.1 - 6.6e-18 64.5 0.8 1.5e-17 63.3 0.8 1.7 1 0 0 1 1 1 1 OCRE domain Chlorophyllase2 PF12740.7 PSC67346.1 - 3.1e-16 59.1 0.0 5.2e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme Nop25 PF09805.9 PSC67346.1 - 2e-14 54.2 16.1 2e-14 54.2 16.1 4.3 5 1 0 5 5 4 1 Nucleolar protein 12 (25kDa) RmlD_sub_bind PF04321.17 PSC67346.1 - 1.3e-11 44.1 0.0 3e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 RmlD substrate binding domain Chlorophyllase PF07224.11 PSC67346.1 - 1.5e-11 43.9 0.0 3.2e-11 42.8 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase Epimerase PF01370.21 PSC67346.1 - 3.2e-09 36.6 0.0 5.6e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family zf-RanBP PF00641.18 PSC67346.1 - 0.00028 20.1 4.6 0.00055 19.2 4.6 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Hydrolase_4 PF12146.8 PSC67346.1 - 0.00031 20.1 0.0 0.00071 18.9 0.0 1.6 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Polysacc_synt_2 PF02719.15 PSC67346.1 - 0.0031 16.7 0.1 0.0052 16.0 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein GDP_Man_Dehyd PF16363.5 PSC67346.1 - 0.0037 16.7 0.0 0.0067 15.9 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 PSC67346.1 - 0.034 13.3 0.0 0.065 12.4 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein HATPase_c PF02518.26 PSC67347.1 - 1.3e-30 106.2 0.0 2.6e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PSC67347.1 - 5.7e-27 94.1 0.0 1.3e-26 93.0 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Bac_rhodopsin PF01036.18 PSC67347.1 - 5.6e-19 68.6 13.3 9.1e-19 67.9 13.3 1.3 1 0 0 1 1 1 1 Bacteriorhodopsin-like protein HisKA PF00512.25 PSC67347.1 - 3.1e-13 49.5 0.4 1.5e-12 47.4 0.1 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain HATPase_c_3 PF13589.6 PSC67347.1 - 0.0015 18.3 0.0 0.0027 17.5 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PepSY_2 PF13670.6 PSC67347.1 - 5.4 7.1 7.2 19 5.4 7.0 2.0 1 1 1 2 2 2 0 Peptidase propeptide and YPEB domain Cob_adeno_trans PF01923.18 PSC67348.1 - 1.6e-59 200.7 0.0 1.8e-59 200.5 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase Utp14 PF04615.13 PSC67348.1 - 0.037 12.6 0.0 0.045 12.3 0.0 1.0 1 0 0 1 1 1 0 Utp14 protein DEAD PF00270.29 PSC67349.1 - 4.9e-40 137.1 0.0 7.9e-40 136.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC67349.1 - 3.1e-20 72.6 0.0 7.4e-20 71.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 PSC67349.1 - 3.9e-12 46.2 0.0 7.9e-12 45.2 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 PSC67349.1 - 7.9e-06 26.0 0.3 1.7e-05 24.9 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit FKBP_C PF00254.28 PSC67350.1 - 7.7e-21 74.2 0.0 2.7e-20 72.5 0.0 1.8 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase Pectate_lyase_3 PF12708.7 PSC67351.1 - 1.3e-27 97.1 12.4 2e-12 47.4 0.1 4.4 4 0 0 4 4 4 3 Pectate lyase superfamily protein Beta_helix PF13229.6 PSC67351.1 - 0.00011 22.1 4.4 0.16 11.8 1.7 2.7 2 1 0 2 2 2 2 Right handed beta helix region Pectinesterase PF01095.19 PSC67351.1 - 0.025 13.3 0.0 4.3 6.0 0.0 2.2 2 0 0 2 2 2 0 Pectinesterase CAP_N PF01213.19 PSC67351.1 - 1.2 8.5 2.4 2.6 7.4 2.4 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Pectate_lyase_3 PF12708.7 PSC67352.1 - 1.3e-27 97.1 12.4 2e-12 47.4 0.1 4.4 4 0 0 4 4 4 3 Pectate lyase superfamily protein Beta_helix PF13229.6 PSC67352.1 - 0.00011 22.1 4.4 0.16 11.8 1.7 2.7 2 1 0 2 2 2 2 Right handed beta helix region Pectinesterase PF01095.19 PSC67352.1 - 0.025 13.3 0.0 4.3 6.0 0.0 2.2 2 0 0 2 2 2 0 Pectinesterase CAP_N PF01213.19 PSC67352.1 - 1.2 8.5 2.4 2.6 7.4 2.4 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Aminotran_4 PF01063.19 PSC67353.1 - 2e-37 129.2 0.0 2.8e-37 128.7 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV DUF4350 PF14258.6 PSC67353.1 - 0.021 15.2 0.3 0.069 13.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) Gp_dh_C PF02800.20 PSC67354.1 - 8.8e-66 220.4 0.0 2.4e-65 219.0 0.0 1.8 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain tRNA-synt_1_2 PF13603.6 PSC67354.1 - 5.6e-56 189.0 0.0 1.7e-55 187.5 0.0 1.9 2 1 0 2 2 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1 PF00133.22 PSC67354.1 - 2.9e-52 177.7 0.0 1.4e-38 132.6 0.0 4.1 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) Pkinase PF00069.25 PSC67354.1 - 2.3e-51 174.7 0.0 8.9e-29 100.6 0.0 3.2 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 PSC67354.1 - 8.8e-35 120.2 0.0 2.4e-20 72.9 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Gp_dh_N PF00044.24 PSC67354.1 - 1.1e-34 118.7 0.0 2.2e-34 117.8 0.0 1.5 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain tRNA-synt_1g PF09334.11 PSC67354.1 - 1.7e-21 76.4 0.0 2.9e-16 59.2 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (M) ATPgrasp_N PF18130.1 PSC67354.1 - 1.3e-19 70.5 0.4 6.4e-19 68.3 0.0 2.5 2 0 0 2 2 1 1 ATP-grasp N-terminal domain ATP-grasp_4 PF13535.6 PSC67354.1 - 1.9e-17 63.3 0.0 5.4e-17 61.9 0.0 1.8 1 1 0 1 1 1 1 ATP-grasp domain Anticodon_1 PF08264.13 PSC67354.1 - 1.2e-14 54.6 0.0 2.9e-14 53.3 0.0 1.6 1 1 0 1 1 1 1 Anticodon-binding domain of tRNA LRR_4 PF12799.7 PSC67354.1 - 2.4e-11 43.7 3.1 0.18 12.3 0.1 8.6 9 2 2 12 12 10 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC67354.1 - 6.8e-09 35.4 12.3 0.061 13.1 0.7 7.7 7 2 2 9 9 8 4 Leucine rich repeat ATPgrasp_Ter PF15632.6 PSC67354.1 - 3.6e-07 30.0 0.0 1.3e-06 28.2 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 PSC67354.1 - 3.7e-07 30.3 0.0 1.5e-06 28.3 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 PSC67354.1 - 4.2e-05 23.2 0.0 0.0001 22.0 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 PSC67354.1 - 0.00035 20.2 0.0 0.00074 19.1 0.0 1.5 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus CPSase_L_D2 PF02786.17 PSC67354.1 - 0.0013 18.3 0.0 0.13 11.8 0.0 2.5 1 1 1 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain APH PF01636.23 PSC67354.1 - 0.002 18.1 0.7 0.002 18.1 0.7 5.4 5 0 0 5 5 5 1 Phosphotransferase enzyme family LRRNT_2 PF08263.12 PSC67354.1 - 0.0022 18.3 0.2 0.007 16.6 0.2 1.9 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain RIO1 PF01163.22 PSC67354.1 - 0.11 12.1 0.0 0.34 10.5 0.0 1.7 2 0 0 2 2 2 0 RIO1 family 2-Hacid_dh_C PF02826.19 PSC67354.1 - 0.11 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DapB_N PF01113.20 PSC67354.1 - 0.14 12.3 0.0 0.39 10.8 0.0 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus tRNA-synt_1e PF01406.19 PSC67354.1 - 0.27 10.6 0.0 6.5 6.0 0.0 2.1 2 0 0 2 2 2 0 tRNA synthetases class I (C) catalytic domain Pkinase_fungal PF17667.1 PSC67354.1 - 0.3 9.8 0.0 0.54 9.0 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Band_7 PF01145.25 PSC67355.1 - 1.3e-22 80.7 5.7 2.5e-22 79.7 5.7 1.5 1 1 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 PSC67355.1 - 1.5e-07 30.8 2.7 2e-07 30.4 2.7 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial SipA_VBS PF17985.1 PSC67355.1 - 0.079 12.9 0.2 25 5.0 0.3 2.7 2 0 0 2 2 2 0 SipA vinculin binding site DUF1191 PF06697.12 PSC67355.1 - 0.094 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Cupin_8 PF13621.6 PSC67356.1 - 5e-06 26.4 0.0 8.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 PSC67356.1 - 9.3e-05 22.0 0.0 0.00011 21.8 0.0 1.1 1 0 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 PSC67356.1 - 0.00023 21.5 0.0 0.00034 21.0 0.0 1.3 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 PSC67356.1 - 0.073 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Cupin domain UCH_1 PF13423.6 PSC67357.1 - 1.3e-54 186.0 0.0 3e-53 181.5 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 PSC67357.1 - 1.1e-18 68.3 0.0 1.7e-18 67.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease UCH PF00443.29 PSC67357.1 - 0.00012 21.7 0.0 0.00043 19.8 0.1 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF5570 PF17731.1 PSC67357.1 - 0.076 13.1 0.3 0.19 11.8 0.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5570) TruB_C PF09142.11 PSC67357.1 - 1.3 8.9 7.6 7.5 6.4 0.2 3.9 3 0 0 3 3 3 0 tRNA Pseudouridine synthase II, C terminal LON_substr_bdg PF02190.16 PSC67358.1 - 8.3e-22 78.1 0.0 1e-21 77.8 0.0 1.1 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain LRR_8 PF13855.6 PSC67359.1 - 9.6e-08 31.7 10.6 8.2e-05 22.3 0.5 5.7 7 0 0 7 7 7 2 Leucine rich repeat LRR_4 PF12799.7 PSC67359.1 - 1.3e-05 25.4 15.6 0.0011 19.3 0.0 7.9 5 3 2 9 9 9 1 Leucine Rich repeats (2 copies) F-box-like PF12937.7 PSC67359.1 - 0.0009 19.1 0.9 0.0032 17.3 0.2 2.3 2 0 0 2 2 2 1 F-box-like His_biosynth PF00977.21 PSC67360.1 - 7.5e-31 107.4 0.2 1e-30 106.9 0.2 1.2 1 0 0 1 1 1 1 Histidine biosynthesis protein TLC PF03219.14 PSC67361.1 - 9.5e-129 430.3 12.6 1.2e-128 430.0 12.6 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter ESCRT-II PF05871.12 PSC67362.1 - 4.5e-41 140.4 0.0 5.5e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit AMPK1_CBM PF16561.5 PSC67363.1 - 5.4e-34 116.3 0.1 1.4e-33 115.0 0.1 1.7 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 PSC67363.1 - 1.7e-21 76.2 4.5 3.3e-21 75.3 4.5 1.5 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 PSC67363.1 - 0.0028 18.0 0.0 0.0057 17.0 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) AMPK1_CBM PF16561.5 PSC67364.1 - 6.6e-34 116.0 0.1 1.4e-33 115.0 0.1 1.5 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 PSC67364.1 - 1.7e-21 76.2 4.5 3.3e-21 75.3 4.5 1.5 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 PSC67364.1 - 0.0027 18.0 0.0 0.0057 17.0 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DUF1731 PF08338.11 PSC67365.1 - 4.5e-20 71.2 0.2 1e-19 70.1 0.1 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 PSC67365.1 - 1e-12 48.0 0.0 1.8e-12 47.2 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PSC67365.1 - 3.2e-08 33.7 0.1 4e-08 33.4 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 PSC67365.1 - 8e-07 28.9 0.0 2.5e-05 24.0 0.1 2.2 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 PSC67365.1 - 1.3e-06 27.7 0.3 1.9e-06 27.2 0.3 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 PSC67365.1 - 0.0024 17.3 0.1 0.82 9.0 0.0 2.8 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 PSC67365.1 - 0.044 14.2 0.1 0.088 13.3 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 PSC67365.1 - 0.14 12.1 1.7 5.8 6.8 0.4 2.3 1 1 0 2 2 2 0 KR domain NAD_binding_4 PF07993.12 PSC67365.1 - 0.14 11.3 2.6 0.44 9.7 0.2 2.4 2 1 0 2 2 2 0 Male sterility protein Thioredoxin PF00085.20 PSC67366.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 1 0 1 1 1 0 Thioredoxin DUF1997 PF09366.10 PSC67368.1 - 2.7e-24 86.0 0.0 3.5e-24 85.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1997) DUF4678 PF15727.5 PSC67368.1 - 0.012 14.9 2.6 0.096 11.9 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4678) MIP PF00230.20 PSC67369.1 - 1.6e-44 152.3 16.0 3.3e-44 151.3 16.0 1.5 1 0 0 1 1 1 1 Major intrinsic protein IMS PF00817.20 PSC67369.1 - 4.2e-40 137.2 0.0 5.3e-39 133.6 0.0 2.3 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 PSC67369.1 - 3.1e-12 47.2 0.0 8.2e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 PSC67369.1 - 3.1e-05 24.0 0.3 0.00026 21.1 0.2 2.4 2 0 0 2 2 2 1 IMS family HHH motif ubiquitin PF00240.23 PSC67370.1 - 1.4e-39 133.6 0.1 3.9e-34 116.2 0.4 3.0 2 1 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.8 PSC67370.1 - 8.8e-19 67.1 0.0 3.4e-16 58.8 0.5 2.9 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 PSC67370.1 - 5.3e-05 23.5 0.0 0.029 14.7 0.1 2.8 2 1 0 2 2 2 1 Ubiquitin-like domain Ubiquitin_2 PF14560.6 PSC67370.1 - 5.7e-05 23.5 0.1 0.00023 21.5 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 PSC67370.1 - 0.0044 17.1 0.2 0.066 13.3 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 PSC67370.1 - 0.0067 16.3 0.0 0.022 14.7 0.0 1.8 2 0 0 2 2 2 1 TANK binding kinase 1 ubiquitin-like domain DUF2407 PF10302.9 PSC67370.1 - 0.014 15.9 0.0 0.072 13.7 0.0 2.0 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain YukD PF08817.10 PSC67370.1 - 0.063 14.0 0.4 6.1 7.6 0.2 3.0 2 1 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD Ubiquitin_4 PF18036.1 PSC67370.1 - 0.094 12.8 3.0 7 6.8 0.2 3.1 4 0 0 4 4 4 0 Ubiquitin-like domain Choline_transpo PF04515.12 PSC67371.1 - 0.0074 15.5 1.5 0.012 14.8 1.5 1.3 1 0 0 1 1 1 1 Plasma-membrane choline transporter DUF5477 PF17571.2 PSC67372.1 - 0.063 13.4 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5477) DUF5477 PF17571.2 PSC67373.1 - 0.063 13.4 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5477) Rhodanese PF00581.20 PSC67375.1 - 3.4e-10 40.4 0.0 2.2e-09 37.8 0.0 2.2 1 1 0 1 1 1 1 Rhodanese-like domain L51_S25_CI-B8 PF05047.16 PSC67376.1 - 1.4e-08 34.5 0.0 3e-08 33.5 0.0 1.5 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RuvA_C PF07499.13 PSC67376.1 - 0.089 13.3 0.2 13 6.3 0.0 2.9 3 0 0 3 3 3 0 RuvA, C-terminal domain Peptidase_M20 PF01546.28 PSC67377.1 - 1.3e-18 67.4 0.0 1.4e-15 57.6 0.0 2.7 2 1 0 2 2 2 2 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PSC67377.1 - 8.6e-06 25.6 0.0 1.8e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Fez1 PF06818.15 PSC67378.1 - 5.7e-05 23.7 11.0 6.6e-05 23.4 10.6 1.3 1 1 0 1 1 1 1 Fez1 DUF641 PF04859.12 PSC67378.1 - 0.0038 17.5 2.2 0.0038 17.5 2.2 2.8 1 1 1 2 2 2 1 Plant protein of unknown function (DUF641) HMMR_N PF15905.5 PSC67378.1 - 0.014 14.9 10.6 0.056 12.9 8.2 2.0 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal DUF4763 PF15960.5 PSC67378.1 - 0.015 14.6 7.0 0.028 13.7 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) ATG16 PF08614.11 PSC67378.1 - 0.016 15.5 15.8 0.016 15.5 15.8 1.8 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) FAM76 PF16046.5 PSC67378.1 - 0.064 12.6 2.8 0.092 12.1 2.8 1.3 1 0 0 1 1 1 0 FAM76 protein FUSC PF04632.12 PSC67378.1 - 0.072 11.6 15.8 0.11 11.0 15.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF4200 PF13863.6 PSC67378.1 - 0.85 10.0 10.8 1.3 9.4 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) DUF2408 PF10303.9 PSC67378.1 - 1.3 9.6 6.4 2.4 8.7 5.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) DUF4407 PF14362.6 PSC67378.1 - 1.3 8.3 14.8 1 8.7 13.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 PSC67378.1 - 1.6 7.7 9.5 2.7 7.0 9.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Spc7 PF08317.11 PSC67378.1 - 1.7 7.4 16.4 3.8 6.3 4.1 2.0 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3496 PF12001.8 PSC67378.1 - 2.1 8.8 6.9 0.74 10.2 2.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3496) DUF724 PF05266.14 PSC67378.1 - 2.3 8.0 11.0 16 5.2 11.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF724) DUF501 PF04417.12 PSC67378.1 - 2.7 7.8 7.2 1.4 8.7 1.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF501) HIP1_clath_bdg PF16515.5 PSC67378.1 - 3 8.5 20.3 0.24 12.0 3.2 2.9 2 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 KxDL PF10241.9 PSC67378.1 - 3.2 8.1 7.8 7.7 6.9 1.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein ERM PF00769.19 PSC67378.1 - 7.6 6.3 21.1 16 5.2 21.1 1.5 1 1 0 1 1 1 0 Ezrin/radixin/moesin family Cep57_CLD_2 PF14197.6 PSC67378.1 - 7.7 6.7 17.6 2.2 8.4 7.3 2.5 1 1 1 2 2 2 0 Centrosome localisation domain of PPC89 DivIC PF04977.15 PSC67378.1 - 8.1 6.3 11.5 6.1 6.7 0.9 3.0 1 1 0 2 2 2 0 Septum formation initiator Fib_alpha PF08702.10 PSC67378.1 - 9.3 6.4 8.2 11 6.2 0.7 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Glyco_transf_5 PF08323.11 PSC67379.1 - 9.8e-47 159.7 0.0 2.8e-46 158.2 0.0 1.7 2 0 0 2 2 2 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 PSC67379.1 - 1.1e-10 41.3 0.0 2e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PSC67379.1 - 2.3e-07 31.3 0.4 8.1e-07 29.5 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 PSC67379.1 - 2.7e-07 31.2 3.6 5.2e-06 27.0 0.0 3.3 3 1 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 PSC67379.1 - 1.6e-06 28.2 0.1 2.3e-05 24.5 0.0 2.8 2 1 0 2 2 2 1 Glycosyltransferase Family 4 bZIP_2 PF07716.15 PSC67379.1 - 0.0083 16.2 1.2 0.013 15.5 1.2 1.3 1 0 0 1 1 1 1 Basic region leucine zipper Herpes_BLRF2 PF05812.12 PSC67379.1 - 0.14 12.3 0.0 0.22 11.6 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein TSC22 PF01166.18 PSC67379.1 - 0.22 11.9 0.2 0.43 10.9 0.2 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family YabA PF06156.13 PSC67379.1 - 0.25 12.0 0.0 0.43 11.2 0.0 1.3 1 0 0 1 1 1 0 Initiation control protein YabA Usp PF00582.26 PSC67380.1 - 6.1e-15 56.0 0.4 2.9e-14 53.8 0.4 2.2 1 1 0 1 1 1 1 Universal stress protein family LpxD PF04613.14 PSC67381.1 - 0.054 13.3 0.3 0.12 12.2 0.0 1.6 2 0 0 2 2 2 0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD CBS PF00571.28 PSC67382.1 - 5.4e-26 90.8 0.4 4.9e-09 36.5 0.0 4.5 4 0 0 4 4 4 4 CBS domain Fasciclin PF02469.22 PSC67383.1 - 3.1e-16 59.8 0.0 1.9e-07 31.3 0.0 3.5 3 1 0 3 3 3 2 Fasciclin domain ATE_C PF04377.15 PSC67384.1 - 2.7e-48 164.0 0.0 3.6e-47 160.4 0.0 2.5 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 PSC67384.1 - 4.2e-23 81.5 1.7 4.2e-23 81.5 1.7 2.3 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus EPL1 PF10513.9 PSC67384.1 - 3.2 8.1 18.8 5.3 7.4 0.5 3.1 3 0 0 3 3 3 0 Enhancer of polycomb-like DUF4770 PF15994.5 PSC67384.1 - 9.7 6.4 16.2 9.3 6.4 5.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) ATE_C PF04377.15 PSC67385.1 - 2.7e-48 164.0 0.0 3.6e-47 160.4 0.0 2.5 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 PSC67385.1 - 4.2e-23 81.5 1.7 4.2e-23 81.5 1.7 2.3 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus EPL1 PF10513.9 PSC67385.1 - 3.2 8.1 18.8 5.3 7.4 0.5 3.1 3 0 0 3 3 3 0 Enhancer of polycomb-like DUF4770 PF15994.5 PSC67385.1 - 9.7 6.4 16.2 9.3 6.4 5.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4770) CLP_protease PF00574.23 PSC67386.1 - 1.7e-39 135.6 0.0 2.3e-31 109.1 0.0 2.1 2 0 0 2 2 2 2 Clp protease Peptidase_S49 PF01343.18 PSC67386.1 - 0.028 14.4 0.2 0.17 11.9 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 Stk19 PF10494.9 PSC67391.1 - 2.4e-33 115.8 0.0 5.7e-33 114.6 0.0 1.6 1 1 0 1 1 1 1 Serine-threonine protein kinase 19 Aa_trans PF01490.18 PSC67392.1 - 1.9e-35 122.4 0.0 4.1e-35 121.3 0.0 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein LRR_8 PF13855.6 PSC67392.1 - 8.7e-08 31.8 0.8 0.00072 19.3 0.3 3.9 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 PSC67392.1 - 0.0083 16.5 8.3 0.012 16.1 0.4 4.6 5 1 0 5 5 5 1 Leucine Rich repeats (2 copies) YL1 PF05764.13 PSC67393.1 - 0.33 11.0 24.2 0.023 14.8 8.7 3.1 3 0 0 3 3 3 0 YL1 nuclear protein SdiA-regulated PF06977.11 PSC67394.1 - 4.1e-05 22.9 0.0 0.18 11.0 0.0 3.7 2 2 0 3 3 3 3 SdiA-regulated RNA_pol_Rpc4 PF05132.14 PSC67395.1 - 9.2e-20 71.6 14.4 2.9e-19 70.0 0.0 3.7 3 1 1 4 4 4 2 RNA polymerase III RPC4 Adeno_PX PF05829.12 PSC67395.1 - 0.023 14.6 0.5 0.023 14.6 0.5 2.6 2 0 0 2 2 2 0 Adenovirus late L2 mu core protein (Protein X) NTF2 PF02136.20 PSC67396.1 - 2.3e-28 99.2 0.1 3.2e-28 98.7 0.1 1.2 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.22 PSC67396.1 - 2.9e-06 27.0 0.0 4.7e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FXMRP1_C_core PF12235.8 PSC67396.1 - 0.037 14.7 1.7 0.037 14.7 1.7 1.7 2 0 0 2 2 2 0 Fragile X-related 1 protein core C terminal DUF3449 PF11931.8 PSC67398.1 - 0.086 12.6 0.0 0.086 12.6 0.0 3.4 1 1 0 2 2 2 0 Domain of unknown function (DUF3449) Trypsin PF00089.26 PSC67399.1 - 7e-31 107.7 0.0 9.5e-31 107.3 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PSC67399.1 - 3.1e-08 34.6 0.8 7.5e-08 33.4 0.8 1.7 1 1 0 1 1 1 1 Trypsin-like peptidase domain ER PF01133.17 PSC67400.1 - 1.2e-23 83.0 0.0 2.3e-23 82.1 0.0 1.4 1 0 0 1 1 1 1 Enhancer of rudimentary Rhodanese PF00581.20 PSC67400.1 - 6e-07 30.0 0.0 1.6e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Nucleoplasmin PF03066.15 PSC67400.1 - 0.36 11.3 1.2 1 9.9 1.0 2.0 1 1 0 1 1 1 0 Nucleoplasmin/nucleophosmin domain SAND PF01342.21 PSC67402.1 - 8.9e-12 44.6 1.0 2e-11 43.4 1.0 1.6 1 0 0 1 1 1 1 SAND domain Peptidase_S8 PF00082.22 PSC67402.1 - 1.5e-07 31.0 0.0 3.9e-06 26.3 0.0 2.3 1 1 1 2 2 2 2 Subtilase family PAPS_reduct PF01507.19 PSC67404.1 - 4.6e-28 98.4 0.0 2.6e-19 69.9 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family MoCF_biosynth PF00994.24 PSC67404.1 - 2.6e-25 88.8 0.0 4.9e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain RIC1 PF07064.13 PSC67405.1 - 2.6e-43 148.2 0.0 8.1e-43 146.6 0.0 1.8 2 0 0 2 2 2 1 RIC1 ANAPC4_WD40 PF12894.7 PSC67405.1 - 3.6e-14 52.8 0.9 0.26 11.6 0.0 6.5 5 2 1 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain TraH PF06122.11 PSC67405.1 - 0.026 13.8 2.3 0.045 13.0 2.3 1.2 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein eIF-3_zeta PF05091.12 PSC67405.1 - 3 6.7 5.4 5.4 5.9 5.4 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) WD40 PF00400.32 PSC67406.1 - 5.5e-07 30.2 9.3 0.00024 21.9 0.3 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat UFD1 PF03152.14 PSC67407.1 - 2.8e-78 261.3 0.0 3.4e-78 261.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 Ribosomal_60s PF00428.19 PSC67407.1 - 0.0013 19.3 6.9 0.0013 19.3 6.9 3.8 3 1 0 3 3 3 1 60s Acidic ribosomal protein Apolipoprotein PF01442.18 PSC67408.1 - 4.6e-12 46.2 46.8 4.8e-06 26.6 11.5 3.8 1 1 3 4 4 4 4 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 PSC67408.1 - 0.16 12.0 8.1 0.45 10.6 4.0 2.9 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) VHL PF01847.16 PSC67409.1 - 9.3e-07 28.7 0.0 1.3e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 VHL beta domain Ribosomal_60s PF00428.19 PSC67409.1 - 0.39 11.3 8.0 0.57 10.8 8.0 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein VHL PF01847.16 PSC67410.1 - 9.3e-07 28.7 0.0 1.3e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 VHL beta domain Ribosomal_60s PF00428.19 PSC67410.1 - 0.39 11.3 8.0 0.57 10.8 8.0 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein ATP-synt_C PF00137.21 PSC67411.1 - 1.2e-24 86.4 30.4 5.4e-17 61.9 10.3 3.0 4 0 0 4 4 4 2 ATP synthase subunit C Bactofilin PF04519.13 PSC67413.1 - 0.0016 18.7 0.3 0.0054 17.0 0.3 1.8 1 1 0 1 1 1 1 Polymer-forming cytoskeletal PRKCSH-like PF12999.7 PSC67414.1 - 1.5e-40 138.8 1.8 1.5e-40 138.8 1.8 2.0 1 1 1 2 2 2 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 PSC67414.1 - 4.2e-26 91.5 0.0 1.2e-25 90.0 0.0 1.8 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 PSC67414.1 - 7.2e-06 26.9 0.5 7.2e-06 26.9 0.5 2.3 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Atg14 PF10186.9 PSC67414.1 - 0.0031 16.7 7.9 0.0031 16.7 7.9 2.4 3 0 0 3 3 3 1 Vacuolar sorting 38 and autophagy-related subunit 14 Herpes_UL6 PF01763.16 PSC67414.1 - 0.053 12.0 0.7 0.9 8.0 0.0 2.1 2 0 0 2 2 2 0 Herpesvirus UL6 like Ldl_recept_a PF00057.18 PSC67414.1 - 0.55 10.5 16.6 0.24 11.7 1.4 2.7 1 1 1 2 2 2 0 Low-density lipoprotein receptor domain class A FAM76 PF16046.5 PSC67414.1 - 1 8.6 10.4 0.036 13.4 0.8 2.8 3 0 0 3 3 3 0 FAM76 protein Helicase_C_2 PF13307.6 PSC67415.1 - 9.9e-51 172.3 0.0 1.9e-50 171.4 0.0 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 PSC67415.1 - 8.5e-45 152.5 0.5 1.4e-44 151.8 0.0 1.6 2 0 0 2 2 2 1 DEAD_2 ResIII PF04851.15 PSC67415.1 - 7e-05 22.9 0.0 0.0011 19.0 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PSC67415.1 - 9.1e-05 22.3 0.1 0.0054 16.5 0.1 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-C3HC4 PF00097.25 PSC67415.1 - 0.0004 20.2 6.7 0.0011 18.8 6.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC67415.1 - 0.00097 19.1 6.4 0.0024 17.8 6.4 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PSC67415.1 - 0.001 18.9 4.7 0.001 18.9 4.7 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PSC67415.1 - 0.0017 18.2 9.3 0.0041 16.9 9.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) HBB PF06777.11 PSC67415.1 - 0.0064 16.2 0.0 0.054 13.2 0.0 2.0 2 0 0 2 2 2 1 Helical and beta-bridge domain Prok-RING_4 PF14447.6 PSC67415.1 - 0.018 14.9 5.7 0.048 13.5 5.7 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PSC67415.1 - 0.064 13.6 8.3 0.19 12.1 8.3 1.9 1 0 0 1 1 1 0 Ring finger domain CopD PF05425.13 PSC67415.1 - 0.083 13.3 3.7 0.37 11.2 0.5 3.0 2 0 0 2 2 2 0 Copper resistance protein D zf-RING_UBOX PF13445.6 PSC67415.1 - 0.23 11.5 5.3 0.67 10.0 5.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 PSC67415.1 - 0.47 10.3 7.4 1.2 9.0 7.4 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 PSC67415.1 - 3.3 8.0 9.5 5 7.4 8.0 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING rve PF00665.26 PSC67416.1 - 6e-19 68.4 0.0 1.3e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC67416.1 - 0.0047 16.7 0.0 0.015 15.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve PF00665.26 PSC67417.1 - 6e-19 68.4 0.0 1.3e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC67417.1 - 0.0047 16.7 0.0 0.015 15.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Ribosomal_L26 PF16906.5 PSC67418.1 - 1.4e-39 134.4 2.0 1.9e-39 134.0 2.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 PSC67418.1 - 3e-08 33.3 4.4 3e-08 33.3 4.4 2.2 2 0 0 2 2 2 1 KOW motif Gpi1 PF05024.15 PSC67419.1 - 3.2e-10 40.4 0.0 6.5e-10 39.4 0.0 1.5 1 1 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) COX5B PF01215.19 PSC67420.1 - 6.3e-10 38.8 0.0 7.4e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb Ribosomal_L6 PF00347.23 PSC67421.1 - 1.5e-39 134.5 4.0 2.7e-20 72.8 0.1 2.2 2 0 0 2 2 2 2 Ribosomal protein L6 DUF2154 PF09922.9 PSC67421.1 - 0.021 14.7 0.0 4.7 7.1 0.0 2.3 2 0 0 2 2 2 0 Cell wall-active antibiotics response 4TMS YvqF YcgR_2 PF12945.7 PSC67421.1 - 0.084 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 Flagellar protein YcgR DNA_ligase_A_N PF04675.14 PSC67421.1 - 0.11 12.8 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 DNA ligase N terminus DUF962 PF06127.11 PSC67422.1 - 2.5e-26 91.6 0.0 5.8e-26 90.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF962) BTB PF00651.31 PSC67422.1 - 2.5e-07 30.9 0.0 1e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain MRP-S23 PF10484.9 PSC67422.1 - 0.003 17.8 0.0 0.005 17.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 MRP-S25 PF13741.6 PSC67422.1 - 0.0041 16.7 4.8 1.1 8.7 0.7 3.1 2 1 1 3 3 3 2 Mitochondrial ribosomal protein S25 DUF962 PF06127.11 PSC67423.1 - 2.5e-26 91.6 0.0 5.8e-26 90.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF962) BTB PF00651.31 PSC67423.1 - 2.5e-07 30.9 0.0 1e-06 28.9 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain MRP-S23 PF10484.9 PSC67423.1 - 0.003 17.8 0.0 0.005 17.1 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein S23 MRP-S25 PF13741.6 PSC67423.1 - 0.0041 16.7 4.8 1.1 8.7 0.7 3.1 2 1 1 3 3 3 2 Mitochondrial ribosomal protein S25 SMC_N PF02463.19 PSC67424.1 - 1.7e-12 47.3 0.0 2.2e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 PSC67424.1 - 3.7e-07 30.5 5.3 4.3e-07 30.2 0.0 3.2 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 PSC67424.1 - 2e-05 24.6 0.0 2.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system Fer2 PF00111.27 PSC67424.1 - 0.0054 16.7 0.1 5.3 7.1 0.0 3.3 1 1 1 2 2 2 2 2Fe-2S iron-sulfur cluster binding domain Mito_carr PF00153.27 PSC67425.1 - 3.4e-74 244.9 2.1 1.7e-23 82.4 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 PSC67426.1 - 3.4e-74 244.9 2.1 1.7e-23 82.3 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein ADIP PF11559.8 PSC67427.1 - 3.7e-24 85.5 7.2 3.7e-24 85.5 7.2 4.8 3 1 2 5 5 5 1 Afadin- and alpha -actinin-Binding Spc7 PF08317.11 PSC67427.1 - 0.00051 19.0 16.3 0.00051 19.0 16.3 3.7 2 1 1 3 3 3 1 Spc7 kinetochore protein Cast PF10174.9 PSC67427.1 - 0.85 7.8 42.8 0.044 12.0 10.3 3.1 2 1 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone GIT_CC PF16559.5 PSC67427.1 - 0.92 9.4 13.0 0.39 10.6 1.2 3.3 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor CTP_transf_1 PF01148.20 PSC67428.1 - 6.4e-21 75.3 16.1 8.8e-21 74.8 16.1 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family XPG_I PF00867.18 PSC67428.1 - 8e-15 55.0 0.0 1.4e-14 54.2 0.0 1.4 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 PSC67428.1 - 0.028 14.9 0.0 0.076 13.5 0.0 1.7 1 1 0 1 1 1 0 XPG N-terminal domain Vps51 PF08700.11 PSC67429.1 - 4.4e-08 33.1 0.0 7.8e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Vps51/Vps67 COG2 PF06148.11 PSC67429.1 - 0.00012 22.2 0.0 0.00028 21.0 0.0 1.6 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Exo84_C PF16528.5 PSC67429.1 - 0.0043 16.9 0.0 0.0075 16.1 0.0 1.3 1 0 0 1 1 1 1 Exocyst component 84 C-terminal CHASE3 PF05227.13 PSC67429.1 - 0.055 13.4 3.2 0.74 9.7 0.5 2.7 2 0 0 2 2 2 0 CHASE3 domain LPMO_10 PF03067.15 PSC67430.1 - 2.9e-23 83.5 0.6 2.9e-23 83.5 0.6 2.1 2 0 0 2 2 2 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading FhuF_C PF11575.8 PSC67430.1 - 2.1 8.4 5.2 0.41 10.6 0.5 2.3 2 0 0 2 2 2 0 FhuF 2Fe-2S C-terminal domain Nucleopor_Nup85 PF07575.13 PSC67431.1 - 1.6e-42 145.9 0.0 2.7e-42 145.1 0.0 1.2 1 0 0 1 1 1 1 Nup85 Nucleoporin Bestrophin PF01062.21 PSC67432.1 - 8.5e-38 130.4 0.4 1.2e-37 129.9 0.4 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Phg_2220_C PF09524.10 PSC67432.1 - 0.17 12.0 0.2 0.37 10.9 0.2 1.5 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) ELP6 PF09807.9 PSC67433.1 - 1e-12 48.0 0.0 7.3e-07 28.9 0.0 2.2 2 0 0 2 2 2 2 Elongation complex protein 6 Hydrophobin_2 PF06766.11 PSC67433.1 - 0.036 14.0 1.1 0.093 12.7 1.1 1.7 1 0 0 1 1 1 0 Fungal hydrophobin Cob_adeno_trans PF01923.18 PSC67434.1 - 6.1 7.0 6.9 20 5.3 6.9 1.8 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Gln-synt_N PF03951.19 PSC67435.1 - 2.4e-15 56.0 0.0 6.2e-15 54.7 0.0 1.7 2 0 0 2 2 2 1 Glutamine synthetase, beta-Grasp domain Gln-synt_C PF00120.24 PSC67435.1 - 3e-15 56.1 0.0 1.3e-13 50.7 0.0 2.3 2 0 0 2 2 2 2 Glutamine synthetase, catalytic domain YidD PF01809.18 PSC67435.1 - 0.0072 16.2 0.0 0.014 15.3 0.0 1.4 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor Kinesin PF00225.23 PSC67436.1 - 4.2e-109 364.5 0.0 1.8e-108 362.4 0.0 2.1 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PSC67436.1 - 4e-25 88.5 0.5 9.3e-23 80.8 0.0 3.7 3 0 0 3 3 3 1 Microtubule binding GAS PF13851.6 PSC67436.1 - 3.4e-05 23.3 7.1 3.4e-05 23.3 7.1 13.9 5 2 9 14 14 14 8 Growth-arrest specific micro-tubule binding FAD_binding_3 PF01494.19 PSC67437.1 - 9.5e-13 48.1 3.8 4.8e-06 26.1 0.4 3.0 1 1 1 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 PSC67437.1 - 1.5e-06 28.3 0.2 1.5e-06 28.3 0.2 2.8 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 PSC67437.1 - 0.00014 21.0 0.0 0.0023 17.0 0.1 2.1 1 1 1 2 2 2 1 Squalene epoxidase HI0933_like PF03486.14 PSC67437.1 - 0.00086 18.1 0.0 0.0014 17.4 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 PSC67437.1 - 0.001 19.6 0.0 0.0021 18.6 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PSC67437.1 - 0.0019 17.8 0.5 0.022 14.4 0.5 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase TrkA_N PF02254.18 PSC67437.1 - 0.0019 18.4 0.0 0.0035 17.6 0.0 1.4 1 0 0 1 1 1 1 TrkA-N domain Pyr_redox_2 PF07992.14 PSC67437.1 - 0.0031 16.8 0.0 0.012 14.9 0.0 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Glu_dehyd_C PF16912.5 PSC67437.1 - 0.013 15.0 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus NAD_binding_9 PF13454.6 PSC67437.1 - 0.015 15.3 0.1 0.027 14.5 0.1 1.5 1 1 0 1 1 1 0 FAD-NAD(P)-binding GIDA PF01134.22 PSC67437.1 - 0.022 13.8 0.0 0.043 12.9 0.0 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 PSC67437.1 - 0.046 13.0 0.0 0.099 11.9 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 PSC67437.1 - 0.17 11.5 0.0 0.37 10.4 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF563 PF04577.14 PSC67438.1 - 6e-35 121.3 0.0 9e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Ephrin_rec_like PF07699.13 PSC67438.1 - 3.5e-10 39.5 13.4 8.2e-06 25.5 2.0 2.5 1 1 1 2 2 2 2 Putative ephrin-receptor like NCD3G PF07562.14 PSC67438.1 - 0.00011 22.0 8.0 0.034 14.1 1.7 2.6 2 0 0 2 2 2 2 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 PSC67438.1 - 0.00022 21.6 7.0 0.03 14.7 0.3 3.1 1 1 1 3 3 3 3 TNFR/NGFR cysteine-rich region Sp38 PF07354.12 PSC67438.1 - 6.3 6.2 12.4 2.9 7.3 2.1 2.3 1 1 1 2 2 2 0 Zona-pellucida-binding protein (Sp38) FtsJ PF01728.19 PSC67439.1 - 2.1e-19 70.3 0.0 3.1e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase S4 PF01479.25 PSC67439.1 - 1.9e-11 43.5 0.0 5e-11 42.1 0.0 1.7 1 0 0 1 1 1 1 S4 domain Methyltransf_11 PF08241.12 PSC67439.1 - 0.00029 21.4 0.1 0.00059 20.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC67439.1 - 0.00037 21.1 0.1 0.00037 21.1 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC67439.1 - 0.063 14.0 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain YqfQ PF14181.6 PSC67439.1 - 2.9 8.0 4.7 4.5 7.4 4.7 1.2 1 0 0 1 1 1 0 YqfQ-like protein FtsJ PF01728.19 PSC67440.1 - 2.1e-19 70.3 0.0 3.1e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase S4 PF01479.25 PSC67440.1 - 1.9e-11 43.5 0.0 4.9e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 S4 domain Methyltransf_11 PF08241.12 PSC67440.1 - 0.00029 21.4 0.1 0.00059 20.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC67440.1 - 0.00037 21.1 0.1 0.00037 21.1 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC67440.1 - 0.063 14.0 0.0 0.11 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain YqfQ PF14181.6 PSC67440.1 - 2.9 8.0 4.7 4.5 7.4 4.7 1.2 1 0 0 1 1 1 0 YqfQ-like protein Acetyltransf_10 PF13673.7 PSC67441.1 - 1e-08 35.2 0.0 2.2e-08 34.1 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PSC67441.1 - 1e-08 35.5 0.0 1.8e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC67441.1 - 2.6e-08 33.7 0.1 7.1e-08 32.3 0.0 1.7 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_1 PF00583.25 PSC67441.1 - 2.9e-08 34.0 0.1 8.7e-08 32.4 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 PSC67441.1 - 5.8e-07 29.6 0.0 0.00051 20.1 0.1 2.6 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PSC67441.1 - 0.0035 18.0 0.0 0.078 13.7 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PSC67441.1 - 0.12 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase GPAT_N PF14829.6 PSC67442.1 - 1.1e-13 50.9 0.0 2.2e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Glycerol-3-phosphate acyltransferase N-terminal Acyltransferase PF01553.21 PSC67442.1 - 1.1e-12 47.7 0.0 1.7e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase LRR_4 PF12799.7 PSC67443.1 - 1e-13 51.2 16.5 0.34 11.4 0.2 12.6 11 4 2 13 13 13 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PSC67443.1 - 1.8e-10 40.0 11.7 2.7 8.3 0.0 12.7 14 0 0 14 14 14 2 Leucine Rich repeat LRR_8 PF13855.6 PSC67443.1 - 3.8e-05 23.3 15.7 5.4 6.9 0.3 11.0 11 2 1 13 13 13 1 Leucine rich repeat F-box-like PF12937.7 PSC67443.1 - 0.00014 21.7 0.3 0.00047 20.0 0.3 2.0 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PSC67443.1 - 0.012 15.5 1.5 0.41 10.6 0.2 3.0 2 0 0 2 2 2 0 F-box domain LRR_1 PF00560.33 PSC67443.1 - 0.024 15.1 21.2 42 5.3 0.0 10.7 12 1 0 12 12 12 0 Leucine Rich Repeat PRCC PF10253.9 PSC67444.1 - 5.4e-13 50.2 14.3 9.4e-13 49.4 14.3 1.4 1 0 0 1 1 1 1 Mitotic checkpoint regulator, MAD2B-interacting Peptidase_S21 PF00716.17 PSC67444.1 - 0.37 10.4 9.0 0.64 9.7 9.0 1.3 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) GIDA PF01134.22 PSC67445.1 - 7.5e-153 509.3 0.0 1.4e-152 508.4 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 PSC67445.1 - 6.4e-65 219.3 0.5 1.4e-63 214.9 0.5 2.2 1 1 0 1 1 1 1 GidA associated domain FAD_oxidored PF12831.7 PSC67445.1 - 4.7e-07 29.5 0.4 4.7e-07 29.5 0.4 2.1 2 0 0 2 2 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PSC67445.1 - 4.8e-06 26.0 0.1 9.2e-06 25.1 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 PSC67445.1 - 0.0061 15.9 1.2 0.0061 15.9 1.2 2.1 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 PSC67445.1 - 0.0068 16.9 0.1 0.018 15.6 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PSC67445.1 - 0.0086 15.4 0.0 0.12 11.6 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PSC67445.1 - 0.0096 14.7 1.2 0.068 11.9 0.3 2.3 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 PSC67445.1 - 0.1 11.8 0.0 0.26 10.5 0.0 1.6 1 0 0 1 1 1 0 Thi4 family ThiF PF00899.21 PSC67445.1 - 0.47 9.8 3.4 0.25 10.7 0.8 1.8 1 1 1 2 2 2 0 ThiF family DAO PF01266.24 PSC67445.1 - 2.4 7.7 15.8 0.57 9.7 0.5 3.5 3 0 0 3 3 3 0 FAD dependent oxidoreductase zf-C2H2_jaz PF12171.8 PSC67446.1 - 0.0061 16.8 0.0 0.0096 16.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PSC67446.1 - 0.026 14.9 0.0 0.043 14.2 0.0 1.3 1 0 0 1 1 1 0 Zinc-finger of C2H2 type Spt20 PF12090.8 PSC67446.1 - 0.056 13.0 4.4 0.11 12.1 4.4 1.4 1 0 0 1 1 1 0 Spt20 family SPX PF03105.19 PSC67446.1 - 5.4 6.8 8.4 9.8 6.0 5.7 2.0 2 0 0 2 2 2 0 SPX domain Neur_chan_memb PF02932.16 PSC67447.1 - 0.00029 21.0 0.0 0.00041 20.5 0.0 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region CobD_Cbib PF03186.13 PSC67447.1 - 0.12 11.6 2.6 0.091 12.0 0.4 1.7 2 0 0 2 2 2 0 CobD/Cbib protein DUF4131 PF13567.6 PSC67447.1 - 1.5 8.4 6.2 0.22 11.2 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Neur_chan_memb PF02932.16 PSC67448.1 - 0.00023 21.3 0.0 0.00028 21.0 0.0 1.2 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region CobD_Cbib PF03186.13 PSC67448.1 - 0.13 11.5 2.6 0.096 11.9 0.4 1.7 2 0 0 2 2 2 0 CobD/Cbib protein DUF4131 PF13567.6 PSC67448.1 - 1.3 8.6 6.2 0.23 11.1 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Fasciclin PF02469.22 PSC67449.1 - 3.7e-25 88.6 0.0 6.7e-13 49.0 0.0 2.3 2 0 0 2 2 2 2 Fasciclin domain VWA_2 PF13519.6 PSC67450.1 - 2.1e-10 41.2 0.0 4.3e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 PSC67450.1 - 2.7e-09 37.5 0.0 1e-08 35.6 0.0 1.8 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 PSC67450.1 - 0.0011 18.9 0.1 0.005 16.8 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain IMS PF00817.20 PSC67451.1 - 2e-47 160.9 0.0 4.4e-47 159.8 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 PSC67451.1 - 6.9e-17 62.2 0.5 6.9e-17 62.2 0.5 2.0 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 PSC67451.1 - 3.5e-06 27.0 0.0 8.9e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 IMS family HHH motif DZR PF12773.7 PSC67451.1 - 0.028 14.4 0.5 0.07 13.2 0.5 1.7 1 0 0 1 1 1 0 Double zinc ribbon SID-1_RNA_chan PF13965.6 PSC67451.1 - 0.044 12.2 0.7 0.07 11.5 0.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 SAPS PF04499.15 PSC67451.1 - 0.078 11.8 9.6 0.025 13.4 5.0 2.1 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein zf-RanBP PF00641.18 PSC67451.1 - 0.15 11.4 3.2 0.34 10.3 3.2 1.6 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others EOS1 PF12326.8 PSC67451.1 - 2.6 8.0 6.7 2.4 8.0 4.0 2.1 2 0 0 2 2 2 0 N-glycosylation protein Otopetrin PF03189.13 PSC67451.1 - 5.4 5.7 5.8 13 4.5 5.8 1.6 1 0 0 1 1 1 0 Otopetrin Membralin PF09746.9 PSC67451.1 - 6.9 5.6 8.1 15 4.5 8.1 1.5 1 0 0 1 1 1 0 Tumour-associated protein LTXXQ PF07813.12 PSC67452.1 - 0.008 16.9 0.3 0.008 16.9 0.3 2.8 3 0 0 3 3 3 1 LTXXQ motif family protein REGB_T4 PF10715.9 PSC67452.1 - 0.03 14.6 0.0 0.055 13.7 0.0 1.5 1 0 0 1 1 1 0 T4-page Endoribonuclease RegB DUF4487 PF14868.6 PSC67453.1 - 0.0032 16.4 1.1 0.0076 15.1 1.1 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4487) SNARE PF05739.19 PSC67454.1 - 3.3e-12 46.2 2.3 3.9e-12 46.0 0.2 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 PSC67454.1 - 6.7e-08 31.6 2.5 1.8e-07 30.2 1.4 2.3 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 PSC67454.1 - 0.00015 21.6 15.1 0.005 16.5 0.7 3.3 3 1 1 4 4 4 2 Syntaxin Syntaxin-18_N PF10496.9 PSC67454.1 - 0.006 16.8 3.2 0.15 12.4 0.0 3.4 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus DUF5344 PF17279.2 PSC67454.1 - 0.06 13.9 2.8 0.66 10.6 0.3 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5344) DUF16 PF01519.16 PSC67454.1 - 0.18 12.3 0.1 0.18 12.3 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function DUF16 DUF3140 PF11338.8 PSC67454.1 - 0.28 11.6 2.7 2 8.9 1.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) SNARE PF05739.19 PSC67455.1 - 3.3e-12 46.2 2.3 3.9e-12 46.0 0.2 2.3 2 0 0 2 2 2 1 SNARE domain Syntaxin-5_N PF11416.8 PSC67455.1 - 6.7e-08 31.5 2.5 1.8e-07 30.2 1.4 2.3 2 0 0 2 2 2 1 Syntaxin-5 N-terminal, Sly1p-binding domain Syntaxin PF00804.25 PSC67455.1 - 3.6e-05 23.5 13.0 0.0035 17.0 0.3 3.3 4 0 0 4 4 4 2 Syntaxin Syntaxin-18_N PF10496.9 PSC67455.1 - 0.0017 18.6 3.3 0.037 14.3 0.0 3.4 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus DUF5344 PF17279.2 PSC67455.1 - 0.061 13.9 2.8 0.66 10.6 0.3 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5344) DUF16 PF01519.16 PSC67455.1 - 0.18 12.3 0.1 0.18 12.3 0.1 4.0 4 0 0 4 4 4 0 Protein of unknown function DUF16 DUF3140 PF11338.8 PSC67455.1 - 0.28 11.6 2.7 2 8.9 1.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3140) S6PP PF05116.13 PSC67456.1 - 6.9e-42 143.7 0.0 1e-41 143.1 0.0 1.2 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase AMPK1_CBM PF16561.5 PSC67456.1 - 5.7e-36 122.6 0.0 5.6e-18 64.9 0.0 2.4 1 1 1 2 2 2 2 Glycogen recognition site of AMP-activated protein kinase Hydrolase_3 PF08282.12 PSC67456.1 - 2.8e-12 46.9 0.0 2.5e-09 37.2 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 PSC67456.1 - 0.0075 16.7 0.1 0.12 12.8 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase IMPDH PF00478.25 PSC67457.1 - 0.13 11.3 0.0 0.14 11.2 0.0 1.0 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain DUF924 PF06041.11 PSC67458.1 - 3e-48 164.4 0.0 3.2e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF924) HD_3 PF13023.6 PSC67459.1 - 1.4e-31 109.7 0.2 3.4e-31 108.4 0.2 1.7 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 PSC67459.1 - 4.3e-08 33.1 0.1 1e-07 31.9 0.1 1.6 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme MAD PF05557.13 PSC67459.1 - 0.024 13.1 8.9 0.017 13.6 5.8 2.0 2 0 0 2 2 2 0 Mitotic checkpoint protein Capsid_VP7 PF17071.5 PSC67459.1 - 0.096 12.0 2.1 0.19 11.0 2.1 1.4 1 0 0 1 1 1 0 Outer capsid protein VP7 Leu_zip PF15294.6 PSC67459.1 - 0.41 10.1 3.8 0.82 9.1 3.8 1.4 1 0 0 1 1 1 0 Leucine zipper UPF0242 PF06785.11 PSC67459.1 - 2.7 8.0 4.6 11 6.1 4.7 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus PDR_CDR PF06422.12 PSC67460.1 - 0.046 13.6 0.6 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 CDR ABC transporter DUF2575 PF10837.8 PSC67460.1 - 3 8.2 6.4 14 6.1 0.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2575) Mg_trans_NIPA PF05653.14 PSC67461.1 - 6.4e-117 389.9 16.5 9.2e-117 389.4 16.5 1.2 1 0 0 1 1 1 1 Magnesium transporter NIPA Ank_2 PF12796.7 PSC67461.1 - 2.3e-09 37.7 2.2 6.9e-09 36.2 2.2 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) EamA PF00892.20 PSC67461.1 - 2.2e-06 27.9 29.2 5e-06 26.7 5.7 3.5 3 0 0 3 3 3 2 EamA-like transporter family Ank PF00023.30 PSC67461.1 - 4.4e-05 23.7 2.1 0.11 13.0 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 PSC67461.1 - 5.2e-05 23.3 0.4 0.13 12.9 0.0 3.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 PSC67461.1 - 0.00038 21.0 0.8 0.0012 19.4 0.3 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC67461.1 - 0.001 19.3 2.4 0.0024 18.2 0.5 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) ABC_membrane PF00664.23 PSC67462.1 - 6.6e-62 209.6 21.1 1e-34 120.5 2.9 4.0 4 0 0 4 4 4 2 ABC transporter transmembrane region ABC_tran PF00005.27 PSC67462.1 - 2.6e-52 177.0 0.0 5.9e-30 104.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter E1-E2_ATPase PF00122.20 PSC67462.1 - 2e-29 102.4 0.1 2e-29 102.4 0.1 3.4 3 0 0 3 3 3 1 E1-E2 ATPase P5-ATPase PF12409.8 PSC67462.1 - 8.5e-14 51.7 0.0 1.7e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 P5-type ATPase cation transporter Hydrolase PF00702.26 PSC67462.1 - 6.8e-10 39.6 3.9 1.3e-06 28.9 1.4 3.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase AAA_16 PF13191.6 PSC67462.1 - 1.1e-05 25.9 0.6 0.093 13.1 0.0 3.2 2 1 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 PSC67462.1 - 1.5e-05 25.0 0.7 0.2 11.8 0.1 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase SMC_N PF02463.19 PSC67462.1 - 3.7e-05 23.3 1.7 2.1 7.7 0.1 4.1 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PSC67462.1 - 0.0007 19.3 0.0 0.44 10.3 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 PSC67462.1 - 0.0017 18.3 0.2 0.27 11.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_7 PF12775.7 PSC67462.1 - 0.0096 15.5 0.1 1 8.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 PSC67462.1 - 0.02 14.1 0.1 0.89 8.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_22 PF13401.6 PSC67462.1 - 0.034 14.4 0.3 17 5.7 0.0 2.8 2 1 0 2 2 2 0 AAA domain DUF87 PF01935.17 PSC67462.1 - 0.039 14.1 0.3 0.63 10.1 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain Cation_ATPase PF13246.6 PSC67462.1 - 0.05 13.7 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 Cation transport ATPase (P-type) Zeta_toxin PF06414.12 PSC67462.1 - 0.067 12.5 0.1 2.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Dynamin_N PF00350.23 PSC67462.1 - 0.11 12.5 4.0 0.44 10.6 0.3 2.3 2 0 0 2 2 2 0 Dynamin family RNA_helicase PF00910.22 PSC67462.1 - 0.16 12.3 0.0 3.6 8.0 0.0 2.5 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.18 PSC67462.1 - 0.21 10.9 0.4 18 4.6 0.2 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_23 PF13476.6 PSC67462.1 - 0.22 12.0 0.0 22 5.5 0.2 2.2 2 0 0 2 2 2 0 AAA domain Clat_adaptor_s PF01217.20 PSC67464.1 - 1.7e-42 144.7 0.6 1.9e-42 144.6 0.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain NPL PF17800.1 PSC67465.1 - 1.6e-13 51.1 0.0 1.6e-13 51.1 0.0 2.7 2 1 0 2 2 2 1 Nucleoplasmin-like domain TFIIF_alpha PF05793.12 PSC67465.1 - 0.00014 20.6 27.3 0.00019 20.1 27.3 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Utp14 PF04615.13 PSC67465.1 - 0.032 12.8 26.7 0.041 12.5 26.7 1.1 1 0 0 1 1 1 0 Utp14 protein Nucleoplasmin PF03066.15 PSC67465.1 - 0.12 12.9 0.0 0.37 11.3 0.0 1.9 1 0 0 1 1 1 0 Nucleoplasmin/nucleophosmin domain DUF1387 PF07139.11 PSC67465.1 - 0.48 10.1 18.0 1.3 8.7 17.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) CLPTM1 PF05602.12 PSC67465.1 - 1.6 7.7 4.9 0.34 9.9 1.0 1.7 1 1 1 2 2 2 0 Cleft lip and palate transmembrane protein 1 (CLPTM1) Hamartin PF04388.12 PSC67465.1 - 6.8 5.2 11.5 8.4 4.9 11.5 1.1 1 0 0 1 1 1 0 Hamartin protein GREB1 PF15782.5 PSC67465.1 - 7.9 3.5 15.0 10 3.1 15.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer KDZ PF18758.1 PSC67466.1 - 2.6e-05 24.0 0.0 0.14 11.8 0.0 2.3 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase KxDL PF10241.9 PSC67466.1 - 0.14 12.5 1.6 0.39 11.0 0.5 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein BTB PF00651.31 PSC67468.1 - 1.1e-05 25.6 0.0 3.1e-05 24.2 0.0 1.7 1 1 0 1 1 1 1 BTB/POZ domain eIF-6 PF01912.18 PSC67469.1 - 6.5e-82 273.7 1.1 8.8e-82 273.3 0.8 1.3 2 0 0 2 2 2 1 eIF-6 family RtcB PF01139.17 PSC67470.1 - 1.9e-150 501.6 0.6 2.2e-150 501.4 0.6 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Rcd1 PF04078.13 PSC67471.1 - 5.1e-128 425.8 0.2 5.8e-128 425.6 0.2 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like TPR_19 PF14559.6 PSC67471.1 - 0.013 16.0 0.1 5.7 7.5 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat DLH PF01738.18 PSC67472.1 - 4.6e-25 88.5 0.1 6.3e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 PSC67472.1 - 0.00011 21.8 0.2 0.049 13.1 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 PSC67472.1 - 0.0023 17.8 0.4 0.18 11.6 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PSC67472.1 - 0.29 11.7 3.4 1.1 9.9 3.4 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family FA_desaturase PF00487.24 PSC67473.1 - 1.5e-36 126.5 10.7 2.6e-36 125.7 10.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Translin PF01997.16 PSC67473.1 - 3.3e-29 102.3 1.0 1.9e-28 99.9 0.7 2.4 2 1 0 2 2 2 1 Translin family Cyt-b5 PF00173.28 PSC67473.1 - 4.3e-11 42.8 0.0 1.1e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ribosomal_L13 PF00572.18 PSC67474.1 - 2.2e-46 157.2 0.0 3.2e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L13 HSP20 PF00011.21 PSC67475.1 - 1.2e-16 60.7 0.1 1.4e-16 60.4 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PSC67475.1 - 2.6e-06 26.9 0.1 5.6e-06 25.8 0.1 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA HSP20 PF00011.21 PSC67476.1 - 1.2e-16 60.7 0.1 1.4e-16 60.4 0.1 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PSC67476.1 - 2.6e-06 26.9 0.1 5.6e-06 25.8 0.1 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA Peptidase_S49 PF01343.18 PSC67477.1 - 1.1e-66 223.5 0.4 8.6e-46 155.7 0.1 3.1 3 0 0 3 3 3 2 Peptidase family S49 Acyl_transf_1 PF00698.21 PSC67477.1 - 1e-21 77.8 1.8 2.3e-21 76.6 1.8 1.7 1 0 0 1 1 1 1 Acyl transferase domain SDH_sah PF01972.16 PSC67477.1 - 4.1e-06 26.0 0.1 6.7e-06 25.3 0.1 1.3 1 0 0 1 1 1 1 Serine dehydrogenase proteinase CLP_protease PF00574.23 PSC67477.1 - 3.5e-05 23.7 0.1 0.00039 20.4 0.1 2.3 2 0 0 2 2 2 1 Clp protease ECH_1 PF00378.20 PSC67477.1 - 0.18 11.1 2.0 13 5.0 2.0 2.5 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Herpes_pp85 PF04637.12 PSC67477.1 - 0.31 9.4 0.1 0.55 8.6 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) ARD PF03079.14 PSC67478.1 - 4.9e-50 169.8 0.0 7.2e-50 169.2 0.0 1.3 1 0 0 1 1 1 1 ARD/ARD' family Carb_anhydrase PF00194.21 PSC67478.1 - 2e-33 116.0 0.0 2.9e-33 115.5 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Cupin_2 PF07883.11 PSC67478.1 - 2e-06 27.4 0.1 5.1e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 Cupin domain Abhydrolase_1 PF00561.20 PSC67478.1 - 0.00048 19.8 0.0 0.66 9.6 0.0 2.3 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC67478.1 - 0.0035 16.6 0.0 0.29 10.3 0.0 2.6 2 0 0 2 2 2 1 Serine aminopeptidase, S33 AraC_binding PF02311.19 PSC67478.1 - 0.0067 16.3 0.1 0.14 12.1 0.0 2.6 2 0 0 2 2 2 1 AraC-like ligand binding domain AXE1 PF05448.12 PSC67478.1 - 0.0068 15.1 1.3 2 7.0 0.0 2.8 3 0 0 3 3 3 2 Acetyl xylan esterase (AXE1) DUF5343 PF17278.2 PSC67478.1 - 0.026 14.6 0.0 7.7 6.6 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function (DUF5343) Ribonuc_red_lgC PF02867.15 PSC67480.1 - 4.4e-181 603.0 0.0 5.4e-181 602.7 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 PSC67480.1 - 1.3e-24 86.0 0.0 6.7e-24 83.7 0.0 2.1 2 0 0 2 2 2 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 PSC67480.1 - 3.2e-18 66.1 0.0 1.1e-17 64.3 0.0 2.0 1 0 0 1 1 1 1 ATP cone domain Glyco_transf_92 PF01697.27 PSC67481.1 - 6.2e-15 55.6 0.0 8.2e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PSC67481.1 - 3.3e-11 43.6 0.0 6.4e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 JmjC PF02373.22 PSC67482.1 - 1.5e-08 35.0 0.0 1.5e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase FemAB PF02388.16 PSC67482.1 - 0.0067 15.3 2.9 0.011 14.6 2.9 1.2 1 0 0 1 1 1 1 FemAB family Cupin_8 PF13621.6 PSC67482.1 - 0.022 14.5 0.0 0.13 12.0 0.0 2.3 3 0 0 3 3 3 0 Cupin-like domain zf-RRN7 PF11781.8 PSC67482.1 - 0.36 10.6 8.8 0.16 11.7 2.2 2.7 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF2126 PF09899.9 PSC67482.1 - 3.7 5.5 5.9 6.1 4.8 5.9 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SpoIIP PF07454.11 PSC67482.1 - 4.8 6.5 8.0 7.8 5.9 8.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) JmjC PF02373.22 PSC67483.1 - 1.5e-08 35.0 0.0 1.5e-08 35.0 0.0 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase FemAB PF02388.16 PSC67483.1 - 0.0067 15.3 2.9 0.011 14.6 2.9 1.2 1 0 0 1 1 1 1 FemAB family Cupin_8 PF13621.6 PSC67483.1 - 0.022 14.5 0.0 0.13 12.0 0.0 2.3 3 0 0 3 3 3 0 Cupin-like domain zf-RRN7 PF11781.8 PSC67483.1 - 0.36 10.6 8.8 0.16 11.7 2.2 2.7 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF2126 PF09899.9 PSC67483.1 - 3.7 5.5 5.9 6.1 4.8 5.9 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SpoIIP PF07454.11 PSC67483.1 - 4.8 6.5 8.0 7.8 5.9 8.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) JmjC PF02373.22 PSC67484.1 - 3.9e-07 30.5 2.0 4.1e-07 30.4 0.0 1.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase FemAB PF02388.16 PSC67484.1 - 0.0068 15.3 2.9 0.011 14.6 2.9 1.2 1 0 0 1 1 1 1 FemAB family Cupin_8 PF13621.6 PSC67484.1 - 0.032 13.9 0.0 0.19 11.4 0.0 2.2 3 0 0 3 3 3 0 Cupin-like domain zf-RRN7 PF11781.8 PSC67484.1 - 0.38 10.5 8.8 0.16 11.7 2.2 2.6 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 eIF-3_zeta PF05091.12 PSC67484.1 - 1 8.2 7.2 2.1 7.2 7.2 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2126 PF09899.9 PSC67484.1 - 3.7 5.5 5.9 6.1 4.8 5.9 1.2 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) SpoIIP PF07454.11 PSC67484.1 - 6.4 6.2 8.4 10 5.5 8.4 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Cupin_8 PF13621.6 PSC67485.1 - 3.1e-15 56.6 0.1 5.9e-14 52.4 0.0 2.1 1 1 1 2 2 2 1 Cupin-like domain JmjC PF02373.22 PSC67485.1 - 2.1e-10 41.1 0.1 4.2e-10 40.1 0.1 1.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase F-box-like PF12937.7 PSC67485.1 - 2.9e-05 23.9 1.3 2.9e-05 23.9 1.3 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PSC67485.1 - 9.1e-05 22.2 1.0 0.00022 21.0 0.4 1.9 2 0 0 2 2 2 1 F-box domain Cupin_4 PF08007.12 PSC67485.1 - 0.002 17.6 0.0 0.005 16.3 0.0 1.6 1 0 0 1 1 1 1 Cupin superfamily protein Ecm29 PF13001.7 PSC67486.1 - 0.014 14.1 0.0 0.024 13.3 0.0 1.3 1 1 0 1 1 1 0 Proteasome stabiliser DUF4158 PF13700.6 PSC67486.1 - 0.021 14.7 0.6 0.089 12.6 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4158) Nucleoporin_C PF03177.14 PSC67487.1 - 5.7e-06 25.4 0.1 6.6e-06 25.1 0.1 1.1 1 0 0 1 1 1 1 Non-repetitive/WGA-negative nucleoporin C-terminal DUF4335 PF14233.6 PSC67487.1 - 2.1 8.2 4.5 8.3 6.3 0.0 2.7 1 1 0 2 2 2 0 Domain of unknown function (DUF4335) MnmE_helical PF12631.7 PSC67488.1 - 1.6e-44 152.5 0.0 2e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 PSC67488.1 - 1.4e-33 115.7 0.0 3e-33 114.5 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 PSC67488.1 - 1.1e-19 70.6 0.0 1.8e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PSC67488.1 - 3.8e-08 33.0 0.0 5.9e-08 32.4 0.0 1.2 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 PSC67488.1 - 2.8e-06 27.5 0.0 4.3e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 Dynamin family ABC_tran PF00005.27 PSC67488.1 - 0.0014 19.1 0.0 0.003 18.1 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_28 PF13521.6 PSC67488.1 - 0.0062 16.8 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 PSC67488.1 - 0.014 15.4 0.0 0.32 10.9 0.1 2.8 3 0 0 3 3 3 0 RsgA GTPase cobW PF02492.19 PSC67488.1 - 0.19 11.3 0.1 6.3 6.4 0.0 2.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain GTP1_OBG PF01018.22 PSC67488.1 - 0.2 11.2 0.0 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 GTP1/OBG MnmE_helical PF12631.7 PSC67489.1 - 1.5e-44 152.6 0.0 1.9e-44 152.3 0.0 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 PSC67489.1 - 1.3e-33 115.7 0.0 3e-33 114.6 0.0 1.6 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 PSC67489.1 - 4e-15 55.9 0.0 7.6e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PSC67489.1 - 4.1e-06 27.0 0.0 6.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 PSC67489.1 - 0.00019 21.0 0.0 0.00038 20.0 0.0 1.5 1 1 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 PSC67489.1 - 0.0015 19.1 0.0 0.0032 18.0 0.0 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 PSC67489.1 - 0.016 15.1 0.0 0.41 10.5 0.0 2.8 3 0 0 3 3 3 0 RsgA GTPase AAA_28 PF13521.6 PSC67489.1 - 0.019 15.2 0.0 0.039 14.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain GTP1_OBG PF01018.22 PSC67489.1 - 0.2 11.3 0.0 0.2 11.3 0.0 1.8 2 0 0 2 2 2 0 GTP1/OBG Pribosyltran PF00156.27 PSC67491.1 - 3.4e-20 72.2 0.1 6.4e-20 71.3 0.1 1.4 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 PSC67491.1 - 0.013 15.0 0.0 0.024 14.1 0.0 1.4 2 0 0 2 2 2 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 PSC67491.1 - 0.02 14.4 0.1 0.03 13.8 0.1 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase rve PF00665.26 PSC67492.1 - 8.3e-19 67.9 0.0 1.8e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC67492.1 - 0.0066 16.2 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Ribosomal_L29e PF01779.17 PSC67493.1 - 4.4e-24 84.5 8.0 4.4e-24 84.5 8.0 1.4 2 0 0 2 2 2 1 Ribosomal L29e protein family Ribosomal_L29e PF01779.17 PSC67494.1 - 4.4e-24 84.5 8.0 4.4e-24 84.5 8.0 1.4 2 0 0 2 2 2 1 Ribosomal L29e protein family Ribosomal_S14 PF00253.21 PSC67496.1 - 6e-18 64.4 3.1 6.6e-18 64.2 3.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e WD40 PF00400.32 PSC67497.1 - 9.9e-39 130.7 17.5 4.9e-10 39.8 0.7 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC67497.1 - 5.6e-06 26.6 0.3 2.1 8.7 0.0 4.6 1 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PSC67497.1 - 0.021 13.5 4.6 0.49 9.0 0.1 3.6 2 2 2 4 4 4 0 Nucleoporin Nup120/160 WD40_like PF17005.5 PSC67497.1 - 0.025 13.9 0.0 0.097 12.0 0.0 1.8 2 0 0 2 2 2 0 WD40-like domain Nucleoporin_N PF08801.11 PSC67497.1 - 0.04 12.7 0.1 2.9 6.5 0.0 3.1 2 1 0 2 2 2 0 Nup133 N terminal like rve PF00665.26 PSC67498.1 - 3.4e-12 46.6 0.0 5.9e-12 45.8 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC67498.1 - 0.004 16.9 0.1 0.011 15.5 0.1 1.7 1 0 0 1 1 1 1 Integrase core domain Keratin_2_head PF16208.5 PSC67499.1 - 0.078 13.1 6.3 0.93 9.6 0.1 2.7 3 0 0 3 3 3 0 Keratin type II head Pyrophosphatase PF00719.19 PSC67500.1 - 4.7e-57 192.3 0.1 5.3e-57 192.1 0.1 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase Glyco_tranf_2_4 PF13704.6 PSC67501.1 - 5.4e-06 26.8 0.3 5.4e-06 26.8 0.3 4.1 2 2 1 3 3 3 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 PSC67501.1 - 0.0077 15.9 0.8 0.081 12.6 0.8 2.4 1 1 0 1 1 1 1 Glycosyltransferase family 92 Utp14 PF04615.13 PSC67501.1 - 0.23 10.0 27.5 0.3 9.6 27.5 1.1 1 0 0 1 1 1 0 Utp14 protein SRP-alpha_N PF04086.13 PSC67501.1 - 1.3 8.8 26.0 2.8 7.8 26.0 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MIP PF00230.20 PSC67502.1 - 1.4e-50 172.1 14.6 2.6e-50 171.2 14.6 1.4 1 0 0 1 1 1 1 Major intrinsic protein E1-E2_ATPase PF00122.20 PSC67502.1 - 1.4e-26 93.1 0.0 4.9e-26 91.4 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase WD40 PF00400.32 PSC67502.1 - 2.9e-16 59.6 6.3 0.00015 22.5 0.2 4.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Cation_ATPase_N PF00690.26 PSC67502.1 - 3.2e-11 42.8 0.0 6.4e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 PSC67502.1 - 2e-07 31.5 3.0 1.9e-05 25.0 0.7 2.6 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase ANAPC4_WD40 PF12894.7 PSC67502.1 - 2.5e-05 24.5 0.0 4.8 7.5 0.0 3.4 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Hydrolase_3 PF08282.12 PSC67502.1 - 0.00038 20.3 0.1 0.0007 19.4 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.21 PSC67502.1 - 0.071 12.8 8.8 0.43 10.3 6.1 3.1 2 1 0 2 2 2 0 Cation transporting ATPase, C-terminus Ribosomal_L1 PF00687.21 PSC67503.1 - 2e-57 194.2 0.1 2.4e-57 194.0 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family HEAT PF02985.22 PSC67504.1 - 1.9e-39 130.3 42.4 1.6e-05 24.7 0.1 14.4 15 0 0 15 15 14 11 HEAT repeat FA_desaturase PF00487.24 PSC67504.1 - 5e-36 124.8 26.8 9.2e-36 124.0 26.8 1.4 1 0 0 1 1 1 1 Fatty acid desaturase HEAT_2 PF13646.6 PSC67504.1 - 4.4e-33 113.5 22.8 7e-07 29.6 0.3 7.7 2 1 6 9 9 9 9 HEAT repeats Vac14_Fab1_bd PF12755.7 PSC67504.1 - 1.5e-11 44.7 0.0 0.002 18.7 0.0 6.1 3 2 3 6 6 6 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 PSC67504.1 - 3.6e-11 42.3 1.7 0.0016 17.1 0.1 4.2 2 1 2 4 4 4 2 Adaptin N terminal region Cnd1 PF12717.7 PSC67504.1 - 5.3e-11 42.8 2.1 0.12 12.4 0.0 5.0 3 1 2 5 5 5 4 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 PSC67504.1 - 3.2e-10 40.3 25.4 0.00064 20.2 0.4 8.4 7 2 4 11 11 10 3 HEAT-like repeat RTP1_C1 PF10363.9 PSC67504.1 - 8.6e-06 25.9 3.0 0.17 12.1 0.0 4.9 4 1 1 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 PSC67504.1 - 0.00016 21.4 0.0 2.2 7.8 0.0 3.5 2 1 1 3 3 3 2 CLASP N terminal DNA_alkylation PF08713.11 PSC67504.1 - 0.011 15.5 0.3 7.4 6.2 0.1 3.5 2 1 2 4 4 4 0 DNA alkylation repair enzyme DRIM PF07539.12 PSC67504.1 - 0.076 11.3 0.4 1.1 7.4 0.6 2.8 2 1 1 3 3 3 0 Down-regulated in metastasis Cohesin_HEAT PF12765.7 PSC67504.1 - 0.35 11.2 2.0 1.2e+02 3.1 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion HEAT_PBS PF03130.16 PSC67504.1 - 0.56 11.0 3.5 22 6.1 0.0 4.9 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Arm PF00514.23 PSC67504.1 - 1 9.5 12.2 30 4.8 0.0 6.8 7 1 1 8 8 8 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 PSC67505.1 - 1.9e-39 130.3 42.4 1.6e-05 24.7 0.1 14.4 15 0 0 15 15 14 11 HEAT repeat FA_desaturase PF00487.24 PSC67505.1 - 5e-36 124.8 26.8 9.2e-36 124.0 26.8 1.4 1 0 0 1 1 1 1 Fatty acid desaturase HEAT_2 PF13646.6 PSC67505.1 - 4.4e-33 113.5 22.8 7e-07 29.6 0.3 7.7 2 1 6 9 9 9 9 HEAT repeats Vac14_Fab1_bd PF12755.7 PSC67505.1 - 1.5e-11 44.7 0.0 0.002 18.7 0.0 6.1 3 2 3 6 6 6 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 PSC67505.1 - 3.6e-11 42.3 1.7 0.0016 17.1 0.1 4.2 2 1 2 4 4 4 2 Adaptin N terminal region Cnd1 PF12717.7 PSC67505.1 - 5.3e-11 42.8 2.1 0.12 12.4 0.0 5.0 3 1 2 5 5 5 4 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 PSC67505.1 - 3.2e-10 40.3 25.4 0.00064 20.2 0.4 8.4 7 2 4 11 11 10 3 HEAT-like repeat RTP1_C1 PF10363.9 PSC67505.1 - 8.6e-06 25.9 3.0 0.17 12.1 0.0 4.9 4 1 1 5 5 5 2 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 PSC67505.1 - 0.00016 21.4 0.0 2.2 7.8 0.0 3.5 2 1 1 3 3 3 2 CLASP N terminal DNA_alkylation PF08713.11 PSC67505.1 - 0.011 15.5 0.3 7.4 6.2 0.1 3.5 2 1 2 4 4 4 0 DNA alkylation repair enzyme DRIM PF07539.12 PSC67505.1 - 0.076 11.3 0.4 1.1 7.4 0.6 2.8 2 1 1 3 3 3 0 Down-regulated in metastasis Cohesin_HEAT PF12765.7 PSC67505.1 - 0.35 11.2 2.0 1.2e+02 3.1 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion HEAT_PBS PF03130.16 PSC67505.1 - 0.56 11.0 3.5 22 6.1 0.0 4.9 5 0 0 5 5 4 0 PBS lyase HEAT-like repeat Arm PF00514.23 PSC67505.1 - 1 9.5 12.2 30 4.8 0.0 6.8 7 1 1 8 8 8 0 Armadillo/beta-catenin-like repeat RAMA PF18755.1 PSC67506.1 - 2.1e-19 69.9 0.0 5.6e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated JAB PF01398.21 PSC67506.1 - 2e-09 37.4 0.0 2e-09 37.4 0.0 1.5 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 PSC67506.1 - 2.6e-07 30.4 0.4 2.6e-07 30.4 0.4 1.9 2 0 0 2 2 2 1 Prokaryotic homologs of the JAB domain YceI PF04264.13 PSC67507.1 - 0.2 12.2 0.3 0.93 10.0 0.1 2.2 2 1 1 3 3 3 0 YceI-like domain YceI PF04264.13 PSC67508.1 - 0.19 12.3 0.3 0.92 10.1 0.1 2.1 2 1 1 3 3 3 0 YceI-like domain HMA PF00403.26 PSC67510.1 - 4e-14 52.8 2.3 4.7e-14 52.6 2.3 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Pro_Al_protease PF02983.14 PSC67510.1 - 0.023 14.7 2.7 0.028 14.5 2.7 1.1 1 0 0 1 1 1 0 Alpha-lytic protease prodomain Flavodoxin_4 PF12682.7 PSC67510.1 - 0.043 13.5 0.2 0.047 13.4 0.2 1.1 1 0 0 1 1 1 0 Flavodoxin DUF211 PF02680.14 PSC67510.1 - 0.045 13.9 0.0 0.053 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 IBN_N PF03810.19 PSC67511.1 - 6.2e-10 38.9 0.0 1.7e-09 37.4 0.0 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain DUF305 PF03713.13 PSC67511.1 - 0.24 11.5 4.3 0.84 9.8 4.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF305) Sec1 PF00995.23 PSC67512.1 - 3.5e-87 294.0 0.0 4.3e-87 293.7 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Ribosomal_60s PF00428.19 PSC67512.1 - 8.8 7.0 9.0 18 6.0 3.8 3.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein SBP PF03110.14 PSC67514.1 - 2.8e-11 43.6 0.0 5.7e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 SBP domain YlbD_coat PF14071.6 PSC67514.1 - 1.3 9.3 8.8 1.5 9.0 7.6 1.6 2 0 0 2 2 2 0 Putative coat protein TFIIA PF03153.13 PSC67514.1 - 4.9 7.0 13.3 6.1 6.7 13.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Elf1 PF05129.13 PSC67515.1 - 8.5e-31 105.8 3.1 9.4e-31 105.7 3.1 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like zf-Sec23_Sec24 PF04810.15 PSC67515.1 - 0.0087 16.1 1.9 2 8.5 0.1 2.5 2 0 0 2 2 2 2 Sec23/Sec24 zinc finger Lar_restr_allev PF14354.6 PSC67515.1 - 0.0095 16.3 4.5 0.012 16.0 4.5 1.4 1 1 0 1 1 1 1 Restriction alleviation protein Lar YABBY PF04690.13 PSC67515.1 - 0.041 14.4 1.0 0.044 14.3 0.2 1.4 1 1 1 2 2 2 0 YABBY protein IIGP PF05049.13 PSC67515.1 - 0.21 10.6 0.0 0.26 10.3 0.0 1.1 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) zf-C2H2_4 PF13894.6 PSC67515.1 - 0.41 11.6 2.6 26 6.0 0.1 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger zinc_ribbon_4 PF13717.6 PSC67515.1 - 0.41 10.6 5.9 1.1 9.2 5.9 1.8 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_10 PF10058.9 PSC67515.1 - 0.62 9.8 4.2 2.1 8.2 0.3 2.2 1 1 1 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein GcpE PF04551.14 PSC67520.1 - 5.5e-155 515.7 0.0 4.8e-154 512.7 0.0 2.4 1 1 0 1 1 1 1 GcpE protein AAA_18 PF13238.6 PSC67520.1 - 4.8e-29 101.5 0.0 1e-28 100.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 PSC67520.1 - 4.2e-08 33.7 0.0 1.3e-07 32.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PSC67520.1 - 8.9e-06 25.9 0.1 0.0022 18.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 PSC67520.1 - 9.3e-05 22.9 0.0 0.00021 21.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) ADK PF00406.22 PSC67520.1 - 0.0011 19.1 0.1 0.0038 17.3 0.0 1.9 2 0 0 2 2 2 1 Adenylate kinase AAA_28 PF13521.6 PSC67520.1 - 0.0019 18.5 0.0 0.0085 16.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PSC67520.1 - 0.0026 18.1 0.0 0.0083 16.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PSC67520.1 - 0.015 15.7 0.1 0.015 15.7 0.1 2.9 3 2 0 3 3 2 0 AAA ATPase domain ATPase PF06745.13 PSC67520.1 - 0.016 14.5 0.0 0.036 13.4 0.0 1.5 1 0 0 1 1 1 0 KaiC RAP PF08373.10 PSC67520.1 - 0.017 15.2 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 RAP domain NTPase_1 PF03266.15 PSC67520.1 - 0.022 14.7 0.0 0.051 13.5 0.0 1.6 1 0 0 1 1 1 0 NTPase DUF2529 PF10740.9 PSC67520.1 - 0.024 14.3 0.0 0.37 10.4 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF2529) AAA_19 PF13245.6 PSC67520.1 - 0.037 14.4 1.1 0.43 10.9 1.1 2.6 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 PSC67520.1 - 0.054 12.5 0.0 0.14 11.2 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_24 PF13479.6 PSC67520.1 - 0.097 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 PSC67520.1 - 0.1 12.3 0.0 0.25 11.1 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain FtsK_SpoIIIE PF01580.18 PSC67520.1 - 0.13 11.6 0.0 0.28 10.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.12 PSC67520.1 - 0.15 11.4 0.1 0.46 9.7 0.1 1.8 1 0 0 1 1 1 0 Zeta toxin WEMBL PF05701.11 PSC67521.1 - 1.7e-05 23.7 12.3 1.7e-05 23.7 12.3 1.5 2 0 0 2 2 2 1 Weak chloroplast movement under blue light ERM PF00769.19 PSC67521.1 - 2e-05 24.5 7.9 2.8e-05 24.0 7.9 1.2 1 0 0 1 1 1 1 Ezrin/radixin/moesin family UPF0242 PF06785.11 PSC67521.1 - 0.007 16.5 5.0 0.01 16.0 5.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus DUF4763 PF15960.5 PSC67521.1 - 0.018 14.4 5.3 0.025 13.9 5.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) AAA_13 PF13166.6 PSC67521.1 - 0.064 11.9 6.0 0.085 11.5 6.0 1.1 1 0 0 1 1 1 0 AAA domain NBP1 PF08537.10 PSC67521.1 - 0.072 12.5 2.0 0.098 12.1 2.0 1.2 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 V_ATPase_I PF01496.19 PSC67521.1 - 0.14 10.0 0.5 0.18 9.7 0.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family KASH_CCD PF14662.6 PSC67521.1 - 0.31 10.9 9.8 0.73 9.6 9.8 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 PSC67521.1 - 0.36 11.3 10.7 0.58 10.6 10.7 1.2 1 0 0 1 1 1 0 Fez1 DUF4407 PF14362.6 PSC67521.1 - 0.8 9.0 24.8 0.066 12.6 14.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) ADIP PF11559.8 PSC67521.1 - 0.83 9.7 18.2 2.5 8.2 14.2 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF812 PF05667.11 PSC67521.1 - 1.3 7.8 8.7 1.8 7.3 8.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) GAS PF13851.6 PSC67521.1 - 1.5 8.2 14.0 3.3 7.0 14.0 1.5 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 PSC67521.1 - 1.7 7.4 13.9 2.4 7.0 13.9 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein CCDC-167 PF15188.6 PSC67521.1 - 2.2 8.7 5.8 10 6.5 3.9 2.2 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 APG6_N PF17675.1 PSC67521.1 - 2.2 8.8 18.6 1.4 9.5 16.1 1.7 1 1 1 2 2 2 0 Apg6 coiled-coil region OmpH PF03938.14 PSC67521.1 - 2.8 8.3 20.8 0.21 11.9 5.8 2.4 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Atg14 PF10186.9 PSC67521.1 - 2.8 6.9 9.1 4.5 6.3 9.1 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Golgin_A5 PF09787.9 PSC67521.1 - 2.9 7.3 9.5 5.1 6.5 9.5 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF3584 PF12128.8 PSC67521.1 - 4.4 4.7 19.6 5.9 4.3 19.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Lectin_N PF03954.14 PSC67521.1 - 4.8 6.9 7.1 86 2.9 7.1 2.2 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain DUF4472 PF14739.6 PSC67521.1 - 5.1 7.9 14.8 4.1 8.2 5.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) TBCA PF02970.16 PSC67521.1 - 7.6 6.9 10.1 35 4.8 10.1 2.0 1 1 0 1 1 1 0 Tubulin binding cofactor A SBP PF03110.14 PSC67522.1 - 7e-24 83.9 0.8 7e-24 83.9 0.8 3.6 4 0 0 4 4 4 1 SBP domain XPA_C PF05181.12 PSC67522.1 - 9.1e-11 41.6 0.0 1.9e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 XPA protein C-terminus Pex14_N PF04695.13 PSC67522.1 - 0.013 16.2 3.6 0.013 16.2 3.6 6.2 3 1 1 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Coiled PF05710.12 PSC67524.1 - 0.016 16.0 1.8 0.023 15.5 1.8 1.2 1 0 0 1 1 1 0 Coiled coil EVE PF01878.18 PSC67525.1 - 6.7e-47 159.1 0.1 1.2e-46 158.3 0.1 1.4 1 0 0 1 1 1 1 EVE domain ERCC4 PF02732.15 PSC67525.1 - 7.6e-15 55.4 0.0 1.4e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain UBA PF00627.31 PSC67525.1 - 0.058 13.3 0.1 0.16 11.9 0.1 1.8 1 0 0 1 1 1 0 UBA/TS-N domain PAP_fibrillin PF04755.12 PSC67525.1 - 0.066 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 PAP_fibrillin zf-MYND PF01753.18 PSC67526.1 - 1.5e-09 37.8 11.5 2.8e-09 36.9 11.5 1.5 1 0 0 1 1 1 1 MYND finger EF-hand_1 PF00036.32 PSC67527.1 - 1.6e-18 64.8 0.0 0.00013 21.2 0.0 5.4 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 PSC67527.1 - 2.6e-18 64.3 0.6 0.00021 21.0 0.0 5.5 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 PSC67527.1 - 2.6e-16 59.8 0.1 1.6e-07 31.7 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 PSC67527.1 - 5.6e-14 51.7 0.1 1.2e-09 37.9 0.0 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 PSC67527.1 - 3.6e-12 45.2 0.3 0.00021 20.6 0.0 4.6 5 0 0 5 5 5 2 EF hand ADIP PF11559.8 PSC67527.1 - 0.0083 16.2 9.9 0.03 14.4 6.0 2.3 2 0 0 2 2 2 1 Afadin- and alpha -actinin-Binding FPP PF05911.11 PSC67527.1 - 0.027 12.7 3.3 0.57 8.3 0.0 2.1 2 0 0 2 2 2 0 Filament-like plant protein, long coiled-coil APG6_N PF17675.1 PSC67527.1 - 0.053 14.0 11.9 4.1 7.9 0.1 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region DASH_Dad2 PF08654.10 PSC67527.1 - 0.078 13.4 0.4 11 6.5 0.0 2.5 2 0 0 2 2 2 0 DASH complex subunit Dad2 TolA_bind_tri PF16331.5 PSC67527.1 - 0.098 12.7 7.0 1.5 9.0 0.1 2.6 3 0 0 3 3 2 0 TolA binding protein trimerisation Spc24 PF08286.11 PSC67527.1 - 0.23 11.7 4.3 13 6.1 1.7 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Filament PF00038.21 PSC67527.1 - 0.3 10.6 7.8 2.2 7.8 4.1 2.2 2 0 0 2 2 2 0 Intermediate filament protein TPR_MLP1_2 PF07926.12 PSC67527.1 - 0.4 10.8 10.6 3.9 7.6 5.1 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Seryl_tRNA_N PF02403.22 PSC67527.1 - 0.71 10.1 3.2 18 5.6 1.2 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Lebercilin PF15619.6 PSC67527.1 - 0.76 9.4 10.7 4 7.0 4.8 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Spc7 PF08317.11 PSC67527.1 - 1.4 7.7 8.3 2.1 7.1 3.0 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 PSC67527.1 - 1.7 8.9 17.3 1.4 9.1 1.2 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) YscO PF07321.12 PSC67527.1 - 2 8.4 16.5 0.3 11.0 8.7 2.3 2 0 0 2 2 2 0 Type III secretion protein YscO Jnk-SapK_ap_N PF09744.9 PSC67527.1 - 2.2 8.5 7.7 14 5.9 3.6 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DivIC PF04977.15 PSC67527.1 - 5.3 6.9 7.3 27 4.6 0.2 2.4 2 0 0 2 2 2 0 Septum formation initiator Csm1_N PF18504.1 PSC67527.1 - 5.7 7.4 8.1 1.3 9.4 0.5 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain CENP-H PF05837.12 PSC67527.1 - 6.1 7.3 6.6 14 6.1 2.3 2.5 2 0 0 2 2 2 0 Centromere protein H (CENP-H) ERM PF00769.19 PSC67527.1 - 6.4 6.5 14.8 8.3 6.1 7.4 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family KELK PF15796.5 PSC67527.1 - 7.8 7.0 9.5 3.6 8.1 4.6 2.3 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase GrpE PF01025.19 PSC67527.1 - 9.6 5.8 7.9 25 4.5 3.6 2.4 2 0 0 2 2 2 0 GrpE EF-hand_6 PF13405.6 PSC67528.1 - 1e-16 59.3 0.5 0.00021 21.0 0.0 5.7 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.32 PSC67528.1 - 1.8e-16 58.3 0.2 0.00013 21.2 0.0 4.9 5 0 0 5 5 4 3 EF hand EF-hand_7 PF13499.6 PSC67528.1 - 5.6e-14 52.3 0.0 1.6e-07 31.7 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 PSC67528.1 - 1.5e-13 50.4 0.0 1.2e-09 37.9 0.0 3.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PSC67528.1 - 6.4e-12 44.4 0.1 0.00021 20.6 0.0 4.1 4 0 0 4 4 4 2 EF hand ADIP PF11559.8 PSC67528.1 - 0.018 15.1 11.8 0.031 14.4 6.0 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 PSC67528.1 - 0.018 15.2 8.2 0.16 12.2 1.0 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 PSC67528.1 - 0.06 13.9 15.2 0.66 10.5 0.7 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 PSC67528.1 - 0.063 13.3 6.4 3.7 7.6 0.1 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DASH_Dad2 PF08654.10 PSC67528.1 - 0.069 13.6 0.4 12 6.4 0.0 2.7 2 0 0 2 2 2 0 DASH complex subunit Dad2 PI3K_P85_iSH2 PF16454.5 PSC67528.1 - 0.098 12.3 1.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Spc24 PF08286.11 PSC67528.1 - 0.13 12.6 5.1 5.4 7.3 0.1 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Spc7 PF08317.11 PSC67528.1 - 0.15 10.9 8.9 2.2 7.1 3.0 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 PSC67528.1 - 0.15 12.5 4.7 5.3 7.4 0.4 2.3 2 0 0 2 2 2 0 Fez1 TMF_TATA_bd PF12325.8 PSC67528.1 - 0.15 12.3 5.4 4.7 7.5 0.2 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Filament PF00038.21 PSC67528.1 - 0.17 11.4 7.5 2.2 7.8 4.1 2.2 2 0 0 2 2 2 0 Intermediate filament protein DUF812 PF05667.11 PSC67528.1 - 0.33 9.8 2.8 3.3 6.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) TPR_MLP1_2 PF07926.12 PSC67528.1 - 0.37 10.8 12.5 3.9 7.5 5.1 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Rx_N PF18052.1 PSC67528.1 - 0.78 10.1 3.9 2.9 8.2 0.3 2.5 2 0 0 2 2 2 0 Rx N-terminal domain TolA_bind_tri PF16331.5 PSC67528.1 - 0.88 9.7 7.1 12 6.1 0.1 2.6 3 0 0 3 3 2 0 TolA binding protein trimerisation Golgin_A5 PF09787.9 PSC67528.1 - 1.1 8.6 7.3 2.8 7.3 3.2 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 HrpB7 PF09486.10 PSC67528.1 - 1.2 9.5 21.7 2.9 8.2 9.1 2.6 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) LRRFIP PF09738.9 PSC67528.1 - 1.3 8.5 8.3 0.16 11.4 2.9 2.0 2 0 0 2 2 2 0 LRRFIP family Lebercilin PF15619.6 PSC67528.1 - 1.9 8.1 12.6 4.1 7.0 4.8 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 PSC67528.1 - 2.6 7.3 7.6 4.7 6.5 0.2 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding YscO PF07321.12 PSC67528.1 - 2.6 8.0 17.4 0.3 11.0 8.7 2.3 2 0 0 2 2 2 0 Type III secretion protein YscO KASH_CCD PF14662.6 PSC67528.1 - 2.8 7.7 9.8 2.3 8.0 0.7 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 PSC67528.1 - 3.2 8.0 8.3 14 5.9 3.6 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Csm1_N PF18504.1 PSC67528.1 - 4.7 7.6 9.4 0.62 10.4 0.9 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain Seryl_tRNA_N PF02403.22 PSC67528.1 - 4.9 7.4 8.9 17 5.7 1.4 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ERM PF00769.19 PSC67528.1 - 5.5 6.7 17.8 8.4 6.1 7.4 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Uso1_p115_C PF04871.13 PSC67528.1 - 7.3 7.0 14.7 5.5 7.4 0.9 2.7 3 0 0 3 3 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region EF-hand_1 PF00036.32 PSC67529.1 - 1.5e-18 64.9 0.0 0.00013 21.2 0.0 5.5 5 0 0 5 5 5 3 EF hand EF-hand_6 PF13405.6 PSC67529.1 - 2.2e-18 64.5 0.6 0.00021 21.0 0.0 5.7 5 0 0 5 5 5 4 EF-hand domain EF-hand_7 PF13499.6 PSC67529.1 - 2.7e-16 59.8 0.1 1.6e-07 31.7 0.1 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 PSC67529.1 - 5.8e-14 51.7 0.1 1.2e-09 37.9 0.0 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 PSC67529.1 - 3.7e-12 45.1 0.3 0.00021 20.6 0.0 4.6 5 0 0 5 5 5 2 EF hand ADIP PF11559.8 PSC67529.1 - 0.018 15.1 11.8 0.031 14.4 6.0 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 PSC67529.1 - 0.019 15.2 8.3 0.16 12.2 1.1 2.5 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 PSC67529.1 - 0.06 13.9 15.2 0.65 10.5 0.7 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region CENP-F_leu_zip PF10473.9 PSC67529.1 - 0.062 13.3 6.4 3.7 7.6 0.1 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DASH_Dad2 PF08654.10 PSC67529.1 - 0.068 13.6 0.4 12 6.4 0.0 2.7 2 0 0 2 2 2 0 DASH complex subunit Dad2 PI3K_P85_iSH2 PF16454.5 PSC67529.1 - 0.097 12.3 1.0 1.3 8.6 0.0 2.2 2 0 0 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Spc24 PF08286.11 PSC67529.1 - 0.13 12.6 5.1 5.4 7.3 0.1 2.4 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 Spc7 PF08317.11 PSC67529.1 - 0.15 11.0 8.9 2.1 7.1 3.0 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein Fez1 PF06818.15 PSC67529.1 - 0.15 12.5 4.7 5.3 7.4 0.4 2.3 2 0 0 2 2 2 0 Fez1 TMF_TATA_bd PF12325.8 PSC67529.1 - 0.15 12.3 5.4 4.7 7.5 0.2 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Filament PF00038.21 PSC67529.1 - 0.17 11.4 7.5 2.2 7.8 4.1 2.2 2 0 0 2 2 2 0 Intermediate filament protein TPR_MLP1_2 PF07926.12 PSC67529.1 - 0.37 10.9 12.5 3.9 7.5 5.1 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DUF812 PF05667.11 PSC67529.1 - 0.44 9.4 3.2 3.4 6.4 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF812) Rx_N PF18052.1 PSC67529.1 - 0.77 10.1 3.9 2.9 8.2 0.3 2.5 2 0 0 2 2 2 0 Rx N-terminal domain TolA_bind_tri PF16331.5 PSC67529.1 - 0.88 9.7 7.1 12 6.1 0.1 2.6 3 0 0 3 3 2 0 TolA binding protein trimerisation Golgin_A5 PF09787.9 PSC67529.1 - 1.1 8.6 7.3 2.8 7.3 3.2 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 HrpB7 PF09486.10 PSC67529.1 - 1.2 9.5 21.7 2.9 8.3 9.1 2.6 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) LRRFIP PF09738.9 PSC67529.1 - 1.3 8.5 8.3 0.16 11.4 2.9 2.0 2 0 0 2 2 2 0 LRRFIP family Lebercilin PF15619.6 PSC67529.1 - 1.9 8.1 12.6 4.1 7.0 4.8 2.3 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease GAS PF13851.6 PSC67529.1 - 2.6 7.4 7.6 4.7 6.5 0.2 2.3 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding YscO PF07321.12 PSC67529.1 - 2.6 8.0 17.4 0.3 11.0 8.7 2.3 2 0 0 2 2 2 0 Type III secretion protein YscO KASH_CCD PF14662.6 PSC67529.1 - 2.8 7.7 9.8 2.3 8.0 0.7 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Jnk-SapK_ap_N PF09744.9 PSC67529.1 - 3.1 8.0 8.3 14 5.9 3.6 2.3 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Csm1_N PF18504.1 PSC67529.1 - 4.6 7.6 9.4 0.62 10.4 0.9 2.7 2 0 0 2 2 2 0 Csm1 N-terminal domain Seryl_tRNA_N PF02403.22 PSC67529.1 - 4.8 7.5 8.9 17 5.7 1.4 2.4 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ERM PF00769.19 PSC67529.1 - 5.5 6.7 17.8 8.4 6.1 7.4 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family Uso1_p115_C PF04871.13 PSC67529.1 - 7.2 7.0 14.7 5.5 7.4 0.9 2.7 3 0 0 3 3 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region zf-4CXXC_R1 PF10497.9 PSC67530.1 - 7.3e-34 116.0 15.1 1.4e-33 115.0 15.1 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 PHD_4 PF16866.5 PSC67530.1 - 0.0012 18.9 6.1 0.0012 18.9 6.1 1.9 2 0 0 2 2 2 1 PHD-finger WHIM1 PF15612.6 PSC67530.1 - 0.0053 16.3 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 DDT PF02791.17 PSC67530.1 - 0.098 13.0 0.0 0.21 11.9 0.0 1.5 1 0 0 1 1 1 0 DDT domain WSD PF15613.6 PSC67530.1 - 0.16 12.5 0.0 0.66 10.5 0.0 2.1 2 0 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif YIF1 PF03878.15 PSC67531.1 - 7e-58 196.0 0.1 8.1e-58 195.8 0.1 1.0 1 0 0 1 1 1 1 YIF1 GATase PF00117.28 PSC67532.1 - 7.2e-55 185.7 0.0 9.1e-55 185.4 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 PSC67532.1 - 8.2e-13 48.6 0.7 3.1e-12 46.7 0.7 1.9 1 1 0 1 1 1 1 Peptidase C26 FA_hydroxylase PF04116.13 PSC67533.1 - 2.5e-13 50.5 15.1 4.3e-13 49.7 15.1 1.4 1 0 0 1 1 1 1 Fatty acid hydroxylase superfamily Cyt-b5 PF00173.28 PSC67533.1 - 3e-11 43.3 0.4 1.1e-10 41.5 0.1 2.0 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain Abhydrolase_3 PF07859.13 PSC67534.1 - 2.1e-14 53.9 0.2 3.6e-14 53.1 0.2 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 PSC67534.1 - 7.4e-11 41.6 0.4 2.1e-10 40.1 0.4 1.6 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 PSC67534.1 - 4.1e-09 36.2 0.3 1.7e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 PSC67534.1 - 1.7e-07 32.1 4.5 2.7e-07 31.4 4.5 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PSC67534.1 - 3.9e-07 30.0 0.6 0.00013 21.8 1.4 2.2 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC67534.1 - 1.5e-05 24.4 0.8 0.00085 18.6 0.8 2.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DLH PF01738.18 PSC67534.1 - 0.0016 18.0 0.0 0.003 17.1 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 PSC67534.1 - 0.013 15.6 0.0 0.1 12.7 0.0 2.1 2 0 0 2 2 2 0 TAP-like protein UPF0564 PF10595.9 PSC67535.1 - 8.6e-09 34.9 0.2 8.6e-09 34.9 0.2 1.7 2 0 0 2 2 2 1 Uncharacterised protein family UPF0564 SMC_N PF02463.19 PSC67536.1 - 3.4e-13 49.5 0.5 4.8e-13 49.0 0.5 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 PSC67536.1 - 3.9e-10 40.6 6.1 3.9e-10 40.6 6.1 4.1 2 2 0 2 2 2 1 AAA domain Metallophos PF00149.28 PSC67536.1 - 0.054 14.0 0.0 0.091 13.2 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase ABC_tran PF00005.27 PSC67536.1 - 0.4 11.2 0.0 0.4 11.2 0.0 4.3 4 2 0 4 4 4 0 ABC transporter BRE1 PF08647.11 PSC67537.1 - 6.4e-08 32.6 2.0 6.4e-08 32.6 2.0 8.3 5 3 3 10 10 10 1 BRE1 E3 ubiquitin ligase UvrC_HhH_N PF08459.11 PSC67537.1 - 0.083 12.8 2.3 0.3 11.0 0.4 2.7 2 0 0 2 2 2 0 UvrC Helix-hairpin-helix N-terminal AsmA_2 PF13502.6 PSC67537.1 - 6.3 6.3 9.0 0.53 9.8 0.5 3.3 3 0 0 3 3 3 0 AsmA-like C-terminal region DUF1682 PF07946.14 PSC67538.1 - 2.4e-67 227.4 0.0 3.3e-67 227.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) Rubrerythrin PF02915.17 PSC67538.1 - 3.3e-40 137.6 0.0 3.3e-40 137.6 0.0 2.7 3 0 0 3 3 3 1 Rubrerythrin FA_desaturase_2 PF03405.14 PSC67538.1 - 0.006 15.5 0.0 1.3 7.8 0.0 2.7 2 0 0 2 2 2 2 Fatty acid desaturase Ferritin_2 PF13668.6 PSC67538.1 - 0.035 14.3 0.0 3.8 7.7 0.0 2.4 1 1 1 2 2 2 0 Ferritin-like domain Na_Ca_ex PF01699.24 PSC67539.1 - 1.3e-36 125.8 39.9 1.6e-18 67.1 19.5 2.3 2 0 0 2 2 2 2 Sodium/calcium exchanger protein DUF4140 PF13600.6 PSC67539.1 - 0.14 12.6 0.4 0.33 11.4 0.4 1.6 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF5428 PF17493.2 PSC67539.1 - 0.54 10.7 1.7 1.1 9.7 1.7 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5428) PhoLip_ATPase_C PF16212.5 PSC67539.1 - 0.99 9.1 5.4 1 9.1 0.4 2.3 2 0 0 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal cEGF PF12662.7 PSC67540.1 - 0.024 14.6 0.9 0.024 14.6 0.9 4.8 3 0 0 3 3 3 0 Complement Clr-like EGF-like B3 PF02362.21 PSC67541.1 - 0.0018 18.1 0.0 0.0029 17.4 0.0 1.3 1 0 0 1 1 1 1 B3 DNA binding domain Macoilin PF09726.9 PSC67541.1 - 0.013 14.1 4.0 0.019 13.6 4.0 1.2 1 0 0 1 1 1 0 Macoilin family PfkB PF00294.24 PSC67542.1 - 1.6e-35 122.9 5.2 2.4e-20 73.0 0.0 2.3 2 0 0 2 2 2 2 pfkB family carbohydrate kinase AFG1_ATPase PF03969.16 PSC67543.1 - 6.8e-95 318.0 0.2 1.5e-90 303.7 0.0 2.3 2 0 0 2 2 2 2 AFG1-like ATPase Bac_DnaA PF00308.18 PSC67543.1 - 0.00093 19.1 0.0 0.0028 17.5 0.0 1.7 1 1 0 1 1 1 1 Bacterial dnaA protein AAA PF00004.29 PSC67543.1 - 0.028 14.8 0.0 0.06 13.8 0.0 1.6 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Fur_reg_FbpA PF13076.6 PSC67543.1 - 0.098 12.4 0.2 0.2 11.4 0.2 1.6 1 0 0 1 1 1 0 Fur-regulated basic protein A AAA_16 PF13191.6 PSC67543.1 - 4.1 7.7 5.1 10 6.4 0.0 3.4 2 1 2 4 4 4 0 AAA ATPase domain NDC10_II PF16787.5 PSC67544.1 - 1.4e-12 47.3 0.0 1.9e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Centromere DNA-binding protein complex CBF3 subunit, domain 2 AAA_7 PF12775.7 PSC67544.1 - 0.03 13.9 0.0 0.059 12.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region Retrotran_gag_3 PF14244.6 PSC67544.1 - 0.12 12.2 0.2 0.28 11.0 0.2 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type RNase_PH PF01138.21 PSC67545.1 - 5.1e-25 88.5 0.0 1.4e-24 87.1 0.0 1.8 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PSC67545.1 - 3.3e-11 43.0 0.2 5.9e-11 42.2 0.2 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Nucleotid_trans PF03407.16 PSC67546.1 - 9.6e-31 107.4 0.0 1.4e-30 106.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase RVT_1 PF00078.27 PSC67546.1 - 2.6e-29 102.3 0.0 8.1e-28 97.4 0.0 2.2 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) PseudoU_synth_2 PF00849.22 PSC67546.1 - 1.3e-25 90.4 0.5 5.7e-25 88.3 0.1 2.0 2 0 0 2 2 2 1 RNA pseudouridylate synthase S4 PF01479.25 PSC67546.1 - 3.2e-08 33.1 0.0 6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 S4 domain RRM_DME PF15628.6 PSC67547.1 - 1.2e-26 92.9 0.0 2.2e-26 92.0 0.0 1.4 1 0 0 1 1 1 1 RRM in Demeter DnaJ PF00226.31 PSC67547.1 - 0.00014 21.9 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Arrestin_N PF00339.29 PSC67548.1 - 7.2e-14 52.1 0.0 1.3e-13 51.3 0.0 1.3 1 0 0 1 1 1 1 Arrestin (or S-antigen), N-terminal domain TGF_beta_GS PF08515.12 PSC67548.1 - 0.34 10.4 3.0 2.3 7.8 0.5 2.7 2 0 0 2 2 2 0 Transforming growth factor beta type I GS-motif SWIB PF02201.18 PSC67550.1 - 7.2e-51 170.0 0.0 9.5e-27 92.7 0.2 2.5 2 0 0 2 2 2 2 SWIB/MDM2 domain DEK_C PF08766.11 PSC67550.1 - 7.9e-16 57.7 0.0 2.5e-15 56.1 0.0 1.9 2 0 0 2 2 2 1 DEK C terminal domain eIF-3c_N PF05470.12 PSC67550.1 - 0.012 14.0 0.0 0.024 12.9 0.0 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Tub_N PF16322.5 PSC67550.1 - 0.028 14.8 15.2 0.25 11.7 2.3 2.4 2 0 0 2 2 2 0 Tubby N-terminal Na_trans_assoc PF06512.13 PSC67550.1 - 0.041 14.2 4.3 0.066 13.5 4.3 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Myc_N PF01056.18 PSC67550.1 - 0.3 10.9 9.6 1.2 9.0 3.6 2.3 2 0 0 2 2 2 0 Myc amino-terminal region Paf1 PF03985.13 PSC67550.1 - 0.38 9.7 15.9 2.3 7.1 0.5 2.3 2 0 0 2 2 2 0 Paf1 TFB6 PF17110.5 PSC67550.1 - 0.89 9.3 6.4 0.25 11.1 0.3 2.3 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH FAM176 PF14851.6 PSC67550.1 - 2.3 7.9 16.1 2.6 7.7 5.6 2.5 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.6 PSC67550.1 - 2.3 8.6 9.3 8.4 6.8 1.2 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TerB_C PF15615.6 PSC67550.1 - 2.5 8.4 16.5 4.6 7.5 0.0 3.7 3 0 0 3 3 3 0 TerB-C domain DUF4564 PF15169.6 PSC67550.1 - 3.6 7.3 6.2 0.66 9.7 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4564) TLP-20 PF06088.11 PSC67550.1 - 4 7.3 6.1 9.6 6.1 0.4 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF3408 PF11888.8 PSC67550.1 - 4.2 7.5 9.6 1.4 9.0 1.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Mis14 PF08641.12 PSC67550.1 - 8.3 6.7 16.4 0.69 10.2 9.3 2.3 2 0 0 2 2 2 0 Kinetochore protein Mis14 like Drc1-Sld2 PF11719.8 PSC67550.1 - 9.9 5.6 10.8 16 4.9 4.1 2.1 2 0 0 2 2 2 0 DNA replication and checkpoint protein SWIB PF02201.18 PSC67551.1 - 7.2e-51 170.0 0.0 9.5e-27 92.7 0.2 2.5 2 0 0 2 2 2 2 SWIB/MDM2 domain DEK_C PF08766.11 PSC67551.1 - 7.9e-16 57.7 0.0 2.5e-15 56.1 0.0 1.9 2 0 0 2 2 2 1 DEK C terminal domain eIF-3c_N PF05470.12 PSC67551.1 - 0.006 15.0 0.0 0.012 13.9 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Tub_N PF16322.5 PSC67551.1 - 0.023 15.1 15.5 0.25 11.7 2.3 2.4 2 0 0 2 2 2 0 Tubby N-terminal Na_trans_assoc PF06512.13 PSC67551.1 - 0.049 13.9 4.7 0.079 13.2 4.7 1.3 1 0 0 1 1 1 0 Sodium ion transport-associated Paf1 PF03985.13 PSC67551.1 - 0.36 9.8 16.2 2.3 7.1 0.5 2.3 2 0 0 2 2 2 0 Paf1 TFB6 PF17110.5 PSC67551.1 - 1.2 8.9 6.8 0.25 11.1 0.5 2.3 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH TerB_C PF15615.6 PSC67551.1 - 1.2 9.4 16.8 4.6 7.5 0.0 3.7 3 0 0 3 3 3 0 TerB-C domain FAM176 PF14851.6 PSC67551.1 - 2 8.0 16.1 2.3 7.9 5.6 2.5 2 0 0 2 2 2 0 FAM176 family TLP-20 PF06088.11 PSC67551.1 - 3.4 7.5 6.8 9.6 6.1 0.4 2.3 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) DUF3408 PF11888.8 PSC67551.1 - 3.4 7.8 9.7 1.1 9.4 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF4564 PF15169.6 PSC67551.1 - 3.6 7.3 6.2 0.66 9.7 1.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4564) PBP1_TM PF14812.6 PSC67551.1 - 4.2 7.8 10.2 8.4 6.8 1.2 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Drc1-Sld2 PF11719.8 PSC67551.1 - 8.9 5.7 11.2 14 5.0 4.6 2.1 2 0 0 2 2 2 0 DNA replication and checkpoint protein Patatin PF01734.22 PSC67552.1 - 4.6e-20 72.7 0.2 2.2e-19 70.5 0.2 2.2 1 0 0 1 1 1 1 Patatin-like phospholipase PRC PF05239.16 PSC67552.1 - 4e-12 46.0 0.0 4.2e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 PRC-barrel domain DUF3336 PF11815.8 PSC67552.1 - 1.9e-10 40.6 0.0 3.3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) BTB PF00651.31 PSC67552.1 - 8.3e-07 29.2 0.0 1.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain PEPCK_ATP PF01293.20 PSC67553.1 - 1.9e-216 719.2 0.0 2.4e-216 718.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Ribul_P_3_epim PF00834.19 PSC67553.1 - 1.1e-64 217.5 0.2 6.6e-64 215.0 0.2 2.1 1 1 0 1 1 1 1 Ribulose-phosphate 3 epimerase family AAA_24 PF13479.6 PSC67553.1 - 0.11 12.3 0.0 0.42 10.3 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sel1 PF08238.12 PSC67554.1 - 2.1e-07 31.4 7.5 0.00034 21.2 0.1 3.7 4 0 0 4 4 4 2 Sel1 repeat F-box-like PF12937.7 PSC67554.1 - 0.0032 17.3 0.0 0.0092 15.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PSC67554.1 - 0.02 14.8 0.3 0.18 11.7 0.3 2.2 1 1 0 1 1 1 0 F-box domain DUF1580 PF07618.11 PSC67554.1 - 0.039 13.6 0.1 0.16 11.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1580) SRC-1 PF08832.10 PSC67554.1 - 0.17 13.0 5.1 0.53 11.4 0.8 2.7 2 0 0 2 2 2 0 Steroid receptor coactivator Erg28 PF03694.13 PSC67555.1 - 1.2e-29 103.0 1.4 1.5e-29 102.6 1.4 1.1 1 0 0 1 1 1 1 Erg28 like protein Virul_fac_BrkB PF03631.15 PSC67555.1 - 0.058 13.0 7.2 0.075 12.6 7.2 1.1 1 0 0 1 1 1 0 Virulence factor BrkB DUF1264 PF06884.11 PSC67556.1 - 8.6e-53 178.4 0.2 1.4e-52 177.7 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1264) ABC1 PF03109.16 PSC67556.1 - 5.9e-27 94.2 0.0 1.3e-26 93.1 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 PSC67556.1 - 0.00068 19.6 2.8 0.011 15.6 0.1 2.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family HTH_31 PF13560.6 PSC67556.1 - 4.8 7.6 9.0 4.9 7.6 3.6 3.1 3 0 0 3 3 3 0 Helix-turn-helix domain LCAT PF02450.15 PSC67557.1 - 3.3e-17 62.8 0.0 4.8e-15 55.6 0.0 2.1 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase HEAT PF02985.22 PSC67557.1 - 1.2e-10 40.7 14.6 0.015 15.5 0.2 6.8 5 0 0 5 5 5 3 HEAT repeat CLASP_N PF12348.8 PSC67557.1 - 1.3e-10 41.2 0.0 1.6e-07 31.1 0.0 3.3 3 0 0 3 3 3 1 CLASP N terminal Arm PF00514.23 PSC67557.1 - 0.00012 22.0 1.5 1.1 9.4 0.1 4.1 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 PSC67557.1 - 0.0021 18.5 1.1 0.0021 18.5 1.1 8.7 8 0 0 8 8 8 3 HEAT-like repeat DUF900 PF05990.12 PSC67557.1 - 0.005 16.4 0.0 0.01 15.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 PSC67557.1 - 0.037 13.3 0.0 0.11 11.7 0.0 1.8 1 0 0 1 1 1 0 Serine aminopeptidase, S33 PGAP1 PF07819.13 PSC67557.1 - 0.07 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 PSC67557.1 - 0.089 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) YqjK PF13997.6 PSC67558.1 - 0.0048 17.1 1.1 0.0089 16.2 1.1 1.4 1 0 0 1 1 1 1 YqjK-like protein zf-MYND PF01753.18 PSC67560.1 - 2.8e-09 36.9 6.7 4.4e-09 36.3 6.7 1.4 1 0 0 1 1 1 1 MYND finger BTB PF00651.31 PSC67561.1 - 0.00078 19.6 0.0 0.0035 17.6 0.0 1.9 1 1 0 1 1 1 1 BTB/POZ domain AAA_6 PF12774.7 PSC67562.1 - 4.8e-121 403.7 0.0 6.4e-67 225.9 0.0 3.3 4 0 0 4 4 4 2 Hydrolytic ATP binding site of dynein motor region DHC_N2 PF08393.13 PSC67562.1 - 9.6e-114 380.6 0.5 2.1e-112 376.2 0.0 2.8 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 PSC67562.1 - 1.9e-90 302.7 0.1 3.6e-89 298.5 0.0 3.0 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 MT PF12777.7 PSC67562.1 - 2.4e-83 280.0 14.0 4.4e-83 279.1 14.0 1.5 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_9 PF12781.7 PSC67562.1 - 3.3e-77 258.5 0.0 5.6e-77 257.8 0.0 1.4 1 0 0 1 1 1 1 ATP-binding dynein motor region Dynein_C PF18199.1 PSC67562.1 - 1.1e-70 238.3 0.0 8.1e-70 235.5 0.0 2.2 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 PSC67562.1 - 9.1e-64 214.3 0.0 9e-59 198.0 0.0 3.9 4 0 0 4 4 4 2 P-loop containing dynein motor region Kelch_5 PF13854.6 PSC67562.1 - 7.6e-45 150.3 0.3 1.3e-07 31.5 0.1 9.7 9 0 0 9 9 9 6 Kelch motif Kelch_4 PF13418.6 PSC67562.1 - 1.6e-38 130.5 11.3 1.4e-06 28.2 0.0 9.4 8 0 0 8 8 8 6 Galactose oxidase, central domain AAA_lid_11 PF18198.1 PSC67562.1 - 1.5e-36 125.7 0.0 2.8e-36 124.8 0.0 1.4 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 PSC67562.1 - 7.1e-35 119.7 0.0 1.4e-31 109.1 0.0 3.2 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain AAA_lid_1 PF17857.1 PSC67562.1 - 1.3e-25 89.5 0.1 5.3e-25 87.5 0.0 2.2 2 0 0 2 2 1 1 AAA+ lid domain Kelch_3 PF13415.6 PSC67562.1 - 8.9e-25 86.4 33.0 4.9e-06 26.7 0.0 10.6 12 0 0 12 12 10 5 Galactose oxidase, central domain Kelch_6 PF13964.6 PSC67562.1 - 4.9e-24 83.8 5.7 2e-05 24.7 0.0 10.5 11 0 0 11 11 11 3 Kelch motif Dynein_AAA_lid PF17852.1 PSC67562.1 - 6.9e-24 84.4 0.2 3.8e-23 82.0 0.0 2.3 2 0 0 2 2 2 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PSC67562.1 - 2.6e-23 82.6 0.0 2.8e-09 37.1 0.0 5.4 4 1 0 4 4 4 4 AAA domain (dynein-related subfamily) Kelch_1 PF01344.25 PSC67562.1 - 1.6e-14 53.2 0.1 0.0073 15.9 0.1 6.5 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 PSC67562.1 - 1.1e-12 47.4 9.8 0.00038 20.3 0.1 8.7 10 0 0 10 10 8 2 Kelch motif Filamin PF00630.19 PSC67562.1 - 2.4e-11 44.4 0.0 5.5e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 Filamin/ABP280 repeat AAA PF00004.29 PSC67562.1 - 2.2e-08 34.6 0.1 0.93 9.9 0.0 5.1 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PSC67562.1 - 7.6e-08 32.9 1.7 0.58 10.5 0.0 6.2 5 0 0 5 5 5 1 AAA ATPase domain TIG PF01833.24 PSC67562.1 - 1.3e-07 31.6 0.0 3.3e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 IPT/TIG domain AAA_18 PF13238.6 PSC67562.1 - 7e-06 26.6 0.6 12 6.5 0.0 5.0 5 0 0 5 5 4 0 AAA domain AAA_19 PF13245.6 PSC67562.1 - 1.2e-05 25.7 0.1 0.013 15.9 0.0 3.8 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 PSC67562.1 - 2.6e-05 24.5 0.1 9.3 6.5 0.0 5.1 5 0 0 5 5 4 0 AAA domain RNA_helicase PF00910.22 PSC67562.1 - 0.00017 21.9 0.2 1.3 9.5 0.0 4.0 4 0 0 4 4 3 1 RNA helicase Rad17 PF03215.15 PSC67562.1 - 0.00047 20.1 0.1 0.0024 17.8 0.0 2.1 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_28 PF13521.6 PSC67562.1 - 0.0019 18.5 0.0 4.6 7.4 0.0 3.9 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 PSC67562.1 - 0.0023 18.5 0.0 2.8 8.5 0.0 4.0 3 0 0 3 3 3 1 ABC transporter TsaE PF02367.17 PSC67562.1 - 0.0027 17.7 0.0 7.9 6.5 0.0 4.3 4 0 0 4 4 4 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 PSC67562.1 - 0.0029 17.8 0.3 0.71 10.0 0.0 4.4 4 0 0 4 4 4 1 AAA domain RuvB_N PF05496.12 PSC67562.1 - 0.012 15.3 0.0 29 4.4 0.0 4.2 4 0 0 4 4 4 0 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 PSC67562.1 - 0.029 13.5 0.2 12 4.9 0.0 3.7 4 0 0 4 4 3 0 Protein of unknown function (DUF815) AAA_11 PF13086.6 PSC67562.1 - 0.069 12.9 0.5 14 5.4 0.0 4.0 4 0 0 4 4 4 0 AAA domain PEARLI-4 PF05278.12 PSC67562.1 - 0.65 9.5 3.3 0.42 10.2 0.7 2.0 2 0 0 2 2 1 0 Arabidopsis phospholipase-like protein (PEARLI 4) IFT57 PF10498.9 PSC67562.1 - 0.83 8.6 3.6 0.33 9.9 0.4 2.0 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 CRISPR_Cse2 PF09485.10 PSC67562.1 - 1.3 9.5 4.7 0.52 10.8 0.3 2.8 2 0 0 2 2 1 0 CRISPR-associated protein Cse2 (CRISPR_cse2) NPA PF16469.5 PSC67562.1 - 4.7 7.8 6.1 7.7 7.1 0.0 3.8 4 0 0 4 4 3 0 Nematode polyprotein allergen ABA-1 DUF1664 PF07889.12 PSC67562.1 - 5.9 6.9 9.6 35 4.5 0.0 4.9 4 1 0 4 4 4 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 PSC67562.1 - 9.1 6.6 15.0 8.4 6.7 2.5 5.1 4 1 0 4 4 3 0 Bacterial protein of unknown function (DUF948) GRA6 PF05084.13 PSC67563.1 - 0.00047 20.2 1.1 0.00047 20.2 1.1 1.8 2 0 0 2 2 2 1 Granule antigen protein (GRA6) eIF-3_zeta PF05091.12 PSC67563.1 - 0.11 11.5 7.8 0.18 10.7 7.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) ALMT PF11744.8 PSC67564.1 - 3.3e-28 98.8 18.4 1.4e-19 70.4 5.2 2.2 2 0 0 2 2 2 2 Aluminium activated malate transporter FUSC PF04632.12 PSC67564.1 - 7.6e-19 67.7 12.7 7.6e-19 67.7 12.7 4.8 4 1 0 5 5 5 2 Fusaric acid resistance protein family FUSC_2 PF13515.6 PSC67564.1 - 0.00028 21.0 46.0 0.0011 19.1 11.0 3.4 3 1 0 3 3 3 2 Fusaric acid resistance protein-like ArAE_2_N PF10337.9 PSC67564.1 - 0.02 13.9 11.1 0.17 10.9 4.6 2.4 2 1 0 2 2 2 0 Putative ER transporter, 6TM, N-terminal Ribosomal_L14e PF01929.17 PSC67565.1 - 2.2e-22 79.3 6.4 3.4e-22 78.7 6.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L14 Pkinase PF00069.25 PSC67566.1 - 4.3e-24 85.3 0.0 5.3e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC67566.1 - 1.2e-06 28.1 0.0 1.6e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PSC67566.1 - 0.0011 17.8 0.0 0.0025 16.7 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PSC67566.1 - 0.024 14.6 0.1 0.12 12.3 0.1 3.5 2 2 0 3 3 3 0 Phosphotransferase enzyme family Ntox8 PF15545.6 PSC67566.1 - 0.076 13.1 0.3 0.19 11.8 0.3 1.7 1 0 0 1 1 1 0 Bacterial toxin 8 Spt20 PF12090.8 PSC67566.1 - 3.9 7.0 9.0 5.8 6.5 9.0 1.1 1 0 0 1 1 1 0 Spt20 family GSHPx PF00255.19 PSC67567.1 - 6.9e-23 80.3 0.0 1.3e-22 79.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione peroxidase IF4E PF01652.18 PSC67569.1 - 1.1e-54 184.5 0.1 1.3e-54 184.3 0.1 1.0 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E DUF1102 PF06510.11 PSC67569.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1102) IDO PF01231.18 PSC67570.1 - 5.3e-59 200.1 0.0 5.1e-55 187.0 0.0 2.0 1 1 1 2 2 2 2 Indoleamine 2,3-dioxygenase DUF3077 PF11275.8 PSC67570.1 - 0.11 12.8 0.6 0.58 10.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3077) IDO PF01231.18 PSC67571.1 - 5.3e-59 200.1 0.0 5.1e-55 187.0 0.0 2.0 1 1 1 2 2 2 2 Indoleamine 2,3-dioxygenase DUF3077 PF11275.8 PSC67571.1 - 0.11 12.8 0.6 0.58 10.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3077) SRR1 PF07985.12 PSC67572.1 - 0.24 11.5 1.9 1.2 9.2 0.1 2.4 2 0 0 2 2 2 0 SRR1 SR-25 PF10500.9 PSC67572.1 - 1 8.9 19.6 1.7 8.2 19.6 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 PSC67572.1 - 8.4 6.7 19.0 13 6.1 19.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF502 PF04367.13 PSC67574.1 - 2.5e-30 104.5 0.0 4.6e-30 103.7 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF502) E1-E2_ATPase PF00122.20 PSC67574.1 - 0.035 13.6 0.3 6.7 6.2 0.0 2.2 2 0 0 2 2 2 0 E1-E2 ATPase SNF2_N PF00176.23 PSC67575.1 - 1.3e-49 168.8 0.0 2.1e-49 168.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC67575.1 - 9.1e-15 55.0 0.0 1.8e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC67575.1 - 3.5e-08 33.6 0.0 8e-08 32.5 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PSC67575.1 - 0.00054 19.8 0.0 0.0014 18.5 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 PSC67575.1 - 0.0041 16.8 0.0 0.0082 15.8 0.0 1.5 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF2075 PF09848.9 PSC67575.1 - 0.047 12.9 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Alpha-amylase PF00128.24 PSC67576.1 - 2.8e-29 102.7 0.0 4.7e-29 102.0 0.0 1.3 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Aa_trans PF01490.18 PSC67577.1 - 3.9e-50 170.8 23.6 4.4e-50 170.6 23.6 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Mersacidin PF16934.5 PSC67577.1 - 0.096 12.5 0.0 0.096 12.5 0.0 3.5 4 0 0 4 4 4 0 Two-component Enterococcus faecalis cytolysin (EFC) Ndr PF03096.14 PSC67577.1 - 0.25 10.0 1.5 0.34 9.6 0.3 1.7 2 0 0 2 2 2 0 Ndr family Glyco_tranf_2_4 PF13704.6 PSC67578.1 - 1.5e-07 31.8 3.4 6.2e-07 29.8 0.1 2.5 3 0 0 3 3 3 1 Glycosyl transferase family 2 Cnd1 PF12717.7 PSC67579.1 - 1.6e-05 25.0 0.1 2.6 8.0 0.0 5.2 6 0 0 6 6 6 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 PSC67579.1 - 9.4e-05 22.8 0.4 9.4e-05 22.8 0.4 11.2 13 1 1 14 14 14 3 HEAT-like repeat Tti2 PF10521.9 PSC67579.1 - 0.00066 19.3 0.1 0.14 11.6 0.0 3.6 4 0 0 4 4 4 1 Tti2 family HEAT PF02985.22 PSC67579.1 - 0.012 15.8 54.8 0.043 14.1 0.1 9.8 12 0 0 12 12 12 0 HEAT repeat MMS19_N PF14500.6 PSC67579.1 - 0.16 11.5 0.8 1.1e+02 2.2 0.0 4.7 7 0 0 7 7 7 0 Dos2-interacting transcription regulator of RNA-Pol-II Arm PF00514.23 PSC67579.1 - 0.6 10.2 25.8 0.14 12.3 0.4 6.7 7 0 0 7 7 7 0 Armadillo/beta-catenin-like repeat RVT_2 PF07727.14 PSC67580.1 - 1.6e-73 247.4 0.0 2.1e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PSC67580.1 - 3.4e-24 85.3 0.0 1.1e-23 83.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Retrotran_gag_2 PF14223.6 PSC67580.1 - 4.8e-22 78.1 0.0 8.9e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 PSC67580.1 - 2.5e-09 36.9 0.0 5.5e-09 35.8 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4219 PF13961.6 PSC67580.1 - 4.2e-05 23.1 0.0 8.8e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) rve_3 PF13683.6 PSC67580.1 - 9.3e-05 22.1 0.0 0.00037 20.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_3 PF14244.6 PSC67580.1 - 0.11 12.3 0.0 0.3 11.0 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Asp_protease_2 PF13650.6 PSC67580.1 - 0.14 12.8 0.0 0.65 10.7 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease zf-C2H2_10 PF16588.5 PSC67580.1 - 0.15 11.9 2.0 0.28 10.9 2.0 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_3 PF13917.6 PSC67580.1 - 0.15 12.0 0.3 0.39 10.7 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle Crr6 PF08847.11 PSC67580.1 - 0.19 11.4 0.0 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 Chlororespiratory reduction 6 zf-CCHC_5 PF14787.6 PSC67580.1 - 0.3 10.8 2.5 0.9 9.3 2.5 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger MutL_C PF08676.11 PSC67581.1 - 1.1e-30 106.4 0.0 7.7e-30 103.6 0.0 2.4 2 1 0 2 2 2 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 PSC67581.1 - 3.4e-21 75.1 0.0 1.2e-20 73.3 0.0 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 PSC67581.1 - 1.3e-12 47.7 0.0 3.1e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PSC67581.1 - 1.9e-06 28.4 0.0 7.7e-06 26.4 0.0 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribonuc_red_sm PF00268.21 PSC67582.1 - 1.3e-107 359.5 0.2 1.5e-107 359.2 0.2 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Bestrophin PF01062.21 PSC67583.1 - 1.5e-12 47.6 0.6 2.3e-12 46.9 0.6 1.3 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel rve PF00665.26 PSC67583.1 - 2.2e-11 44.0 0.0 5.1e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain adh_short PF00106.25 PSC67583.1 - 1e-09 38.1 0.0 8.7e-09 35.1 0.0 2.3 2 1 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC67583.1 - 4.5e-07 29.7 0.0 2.7e-06 27.1 0.0 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Peptidase_S9 PF00326.21 PSC67583.1 - 1.1e-05 25.0 0.0 0.0011 18.5 0.0 2.3 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 PSC67583.1 - 0.0002 21.0 0.0 0.00082 19.0 0.0 1.9 2 0 0 2 2 2 1 Dienelactone hydrolase family AXE1 PF05448.12 PSC67583.1 - 0.0066 15.2 0.0 0.011 14.5 0.0 1.2 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) rve_3 PF13683.6 PSC67583.1 - 0.013 15.3 0.0 0.037 13.8 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain BAAT_C PF08840.11 PSC67583.1 - 0.015 15.2 0.0 0.037 14.0 0.0 1.6 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal PhoPQ_related PF10142.9 PSC67583.1 - 0.017 13.8 0.0 0.027 13.1 0.0 1.2 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein DUF2048 PF09752.9 PSC67583.1 - 0.15 11.1 0.0 0.48 9.5 0.0 1.7 2 0 0 2 2 2 0 Abhydrolase domain containing 18 Abhydrolase_7 PF12715.7 PSC67583.1 - 0.17 11.1 0.0 0.7 9.1 0.0 1.9 2 0 0 2 2 2 0 Abhydrolase family Abhydrolase_3 PF07859.13 PSC67583.1 - 0.21 11.4 2.1 0.25 11.2 0.5 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 PSC67583.1 - 0.33 10.5 3.3 0.14 11.7 0.5 1.8 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) WD40 PF00400.32 PSC67584.1 - 1.3e-09 38.5 0.1 1.9e-05 25.3 0.0 2.9 2 0 0 2 2 2 2 WD domain, G-beta repeat F-box-like PF12937.7 PSC67584.1 - 0.41 10.6 2.2 6.7 6.7 0.3 2.6 2 0 0 2 2 2 0 F-box-like WD40 PF00400.32 PSC67585.1 - 6.4e-09 36.3 2.3 2.4e-05 25.0 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat F-box-like PF12937.7 PSC67585.1 - 0.68 9.9 2.2 8.3 6.4 0.3 2.5 2 0 0 2 2 2 0 F-box-like DUF3754 PF12576.8 PSC67586.1 - 3.3e-15 56.2 0.0 6.1e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3754) AAA_5 PF07728.14 PSC67588.1 - 9.1e-120 395.0 0.0 9.1e-22 77.5 0.0 9.5 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 PSC67588.1 - 1e-47 160.7 0.0 1.7e-13 50.7 0.0 6.8 6 0 0 6 6 6 4 Midasin AAA lid domain AAA_3 PF07726.11 PSC67588.1 - 1.6e-30 105.7 0.0 1.4e-11 44.4 0.0 6.6 8 0 0 8 8 6 3 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 PSC67588.1 - 8.4e-29 99.8 0.0 3.2e-28 97.9 0.0 2.1 2 0 0 2 2 1 1 Midasin AAA lid domain AAA PF00004.29 PSC67588.1 - 4.2e-27 95.2 0.2 0.00012 22.5 0.0 6.6 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 PSC67588.1 - 9.6e-23 80.6 0.0 4e-05 23.2 0.0 5.9 6 0 0 6 6 6 5 P-loop containing dynein motor region AAA_6 PF12774.7 PSC67588.1 - 5e-19 68.4 0.0 0.025 13.5 0.0 7.2 7 0 0 7 7 7 5 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 PSC67588.1 - 1.4e-18 67.5 1.7 0.013 15.7 0.1 7.1 6 0 0 6 6 6 4 AAA domain Dynein_heavy PF03028.15 PSC67588.1 - 1.8e-16 60.3 0.0 0.096 12.8 0.0 6.7 7 0 0 7 7 6 4 Dynein heavy chain region D6 P-loop domain AAA_33 PF13671.6 PSC67588.1 - 3.4e-14 53.2 0.9 0.12 12.6 0.0 7.2 6 0 0 6 6 6 3 AAA domain TsaE PF02367.17 PSC67588.1 - 3e-12 46.7 7.6 0.0039 17.2 0.1 6.4 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 PSC67588.1 - 6.7e-12 45.4 0.4 0.016 14.9 0.0 5.6 6 0 0 6 6 5 3 Sigma-54 interaction domain AAA_18 PF13238.6 PSC67588.1 - 7.3e-12 46.0 0.8 0.24 11.9 0.0 6.3 6 0 0 6 6 5 1 AAA domain ABC_tran PF00005.27 PSC67588.1 - 2.2e-10 41.2 0.3 0.15 12.6 0.0 5.8 5 0 0 5 5 5 2 ABC transporter AAA_14 PF13173.6 PSC67588.1 - 1.3e-09 38.1 0.0 0.022 14.8 0.0 4.9 5 0 0 5 5 4 2 AAA domain AAA_29 PF13555.6 PSC67588.1 - 1.7e-09 37.3 1.5 3 7.7 0.0 6.2 6 0 0 6 6 6 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 PSC67588.1 - 6.8e-09 36.1 0.4 0.69 10.3 0.0 5.8 5 0 0 5 5 5 1 RNA helicase Zeta_toxin PF06414.12 PSC67588.1 - 3.3e-08 33.0 1.2 0.57 9.4 0.0 5.7 6 0 0 6 6 6 1 Zeta toxin T2SSE PF00437.20 PSC67588.1 - 5.5e-08 32.2 0.7 0.1 11.6 0.0 4.9 5 0 0 5 5 5 2 Type II/IV secretion system protein RuvB_N PF05496.12 PSC67588.1 - 1.1e-07 31.8 2.3 0.75 9.5 0.0 6.0 6 0 0 6 6 6 2 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 PSC67588.1 - 2.8e-07 30.0 0.4 0.56 9.3 0.1 5.1 5 0 0 5 5 5 2 Protein of unknown function (DUF815) AAA_19 PF13245.6 PSC67588.1 - 2.9e-07 30.9 2.6 0.94 9.8 0.1 6.0 5 0 0 5 5 4 1 AAA domain NACHT PF05729.12 PSC67588.1 - 1.6e-06 28.2 10.6 0.06 13.3 0.3 5.9 6 0 0 6 6 6 2 NACHT domain RsgA_GTPase PF03193.16 PSC67588.1 - 2.4e-06 27.6 0.2 0.5 10.3 0.1 4.7 5 0 0 5 5 5 1 RsgA GTPase Sigma54_activ_2 PF14532.6 PSC67588.1 - 1.4e-05 25.3 0.2 0.18 11.9 0.0 4.5 5 0 0 5 5 4 1 Sigma-54 interaction domain AAA_24 PF13479.6 PSC67588.1 - 1.7e-05 24.6 0.0 4.1 7.1 0.0 5.2 6 0 0 6 6 5 0 AAA domain IstB_IS21 PF01695.17 PSC67588.1 - 3e-05 23.8 2.8 0.6 9.8 0.0 5.3 5 0 0 5 5 5 1 IstB-like ATP binding protein PduV-EutP PF10662.9 PSC67588.1 - 9.2e-05 22.2 0.6 0.44 10.3 0.1 4.2 5 0 0 5 5 4 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 PSC67588.1 - 0.00014 22.3 11.9 0.0014 19.1 8.1 12.8 13 2 1 14 14 6 5 AAA ATPase domain AAA_28 PF13521.6 PSC67588.1 - 0.00019 21.7 17.5 1.9 8.7 0.0 7.3 7 0 0 7 7 5 1 AAA domain AAA_8 PF12780.7 PSC67588.1 - 0.00045 19.6 0.4 0.3 10.4 0.0 3.9 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 MMR_HSR1 PF01926.23 PSC67588.1 - 0.00048 20.2 0.2 17 5.6 0.0 4.5 4 0 0 4 4 4 0 50S ribosome-binding GTPase AAA_11 PF13086.6 PSC67588.1 - 0.00054 19.8 0.9 37 4.0 0.0 5.7 6 0 0 6 6 6 0 AAA domain TIP49 PF06068.13 PSC67588.1 - 0.0012 18.2 3.3 2.8 7.1 0.1 4.2 4 0 0 4 4 4 1 TIP49 P-loop domain Rad17 PF03215.15 PSC67588.1 - 0.0022 17.9 1.2 8.6 6.2 0.0 5.1 6 0 0 6 6 6 0 Rad17 P-loop domain Roc PF08477.13 PSC67588.1 - 0.0026 18.0 1.6 2 8.7 0.1 4.6 5 0 0 5 5 5 1 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 PSC67588.1 - 0.0049 16.8 4.5 3.6 7.5 0.4 4.4 4 0 0 4 4 4 0 NTPase IPT PF01745.16 PSC67588.1 - 0.0058 16.1 0.5 0.93 8.8 0.0 3.2 3 0 0 3 3 3 1 Isopentenyl transferase ATPase PF06745.13 PSC67588.1 - 0.007 15.7 0.6 5.5 6.3 0.1 3.8 4 0 0 4 4 4 0 KaiC Mg_chelatase PF01078.21 PSC67588.1 - 0.013 14.9 18.3 1.3 8.4 0.3 8.0 9 1 0 10 10 8 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 PSC67588.1 - 0.017 15.7 11.2 8.7 6.8 0.0 6.2 6 0 0 6 6 5 0 AAA domain dNK PF01712.19 PSC67588.1 - 0.02 14.8 1.1 48 3.7 0.0 4.0 4 0 0 4 4 4 0 Deoxynucleoside kinase Viral_helicase1 PF01443.18 PSC67588.1 - 0.021 14.6 0.0 23 4.6 0.0 3.9 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 PSC67588.1 - 0.022 14.5 0.1 21 4.8 0.0 3.7 4 0 0 4 4 3 0 DEAD/DEAH box helicase ATPase_2 PF01637.18 PSC67588.1 - 0.033 14.1 0.0 27 4.6 0.0 3.8 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea cobW PF02492.19 PSC67588.1 - 0.033 13.8 8.2 7.5 6.1 0.0 4.9 6 0 0 6 6 5 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 PSC67588.1 - 0.035 13.7 8.2 3.8 7.1 0.3 5.3 6 0 0 6 6 6 0 SRP54-type protein, GTPase domain TniB PF05621.11 PSC67588.1 - 0.04 13.3 0.0 7.7 5.9 0.0 4.0 6 0 0 6 6 4 0 Bacterial TniB protein Bac_DnaA PF00308.18 PSC67588.1 - 0.046 13.5 0.0 2.4 8.0 0.0 2.6 3 0 0 3 3 2 0 Bacterial dnaA protein ResIII PF04851.15 PSC67588.1 - 0.074 13.1 0.2 10 6.1 0.0 3.5 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit PhoH PF02562.16 PSC67588.1 - 0.085 12.3 0.1 16 4.8 0.0 3.5 4 0 0 4 4 3 0 PhoH-like protein DAP3 PF10236.9 PSC67588.1 - 0.087 12.0 2.3 6.6 5.8 0.1 3.5 4 0 0 4 4 3 0 Mitochondrial ribosomal death-associated protein 3 MCM PF00493.23 PSC67588.1 - 0.18 10.9 0.0 24 3.9 0.0 3.6 4 0 0 4 4 4 0 MCM P-loop domain SRPRB PF09439.10 PSC67588.1 - 0.21 11.0 0.3 26 4.2 0.0 3.1 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit UvrD-helicase PF00580.21 PSC67588.1 - 0.22 11.0 1.2 31 3.9 0.0 3.2 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain NB-ARC PF00931.22 PSC67588.1 - 2.1 7.5 3.7 1.9 7.6 0.1 2.6 4 0 0 4 4 2 0 NB-ARC domain CPT PF07931.12 PSC67588.1 - 2.5 7.9 11.2 3.4 7.5 0.1 5.6 6 1 0 6 6 5 0 Chloramphenicol phosphotransferase-like protein ATP_bind_1 PF03029.17 PSC67588.1 - 2.9 7.6 5.3 33 4.2 0.1 4.1 5 0 0 5 5 4 0 Conserved hypothetical ATP binding protein AAA_5 PF07728.14 PSC67589.1 - 9.1e-120 395.0 0.0 9.1e-22 77.5 0.0 9.5 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 PSC67589.1 - 1e-47 160.7 0.0 1.7e-13 50.7 0.0 6.8 6 0 0 6 6 6 4 Midasin AAA lid domain AAA_3 PF07726.11 PSC67589.1 - 1.6e-30 105.7 0.0 1.4e-11 44.4 0.0 6.6 8 0 0 8 8 6 3 ATPase family associated with various cellular activities (AAA) AAA_lid_5 PF17865.1 PSC67589.1 - 8.4e-29 99.8 0.0 3.2e-28 97.9 0.0 2.1 2 0 0 2 2 1 1 Midasin AAA lid domain AAA PF00004.29 PSC67589.1 - 4.2e-27 95.2 0.2 0.00012 22.5 0.0 6.6 6 0 0 6 6 6 6 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 PSC67589.1 - 9.6e-23 80.6 0.0 4e-05 23.2 0.0 5.9 6 0 0 6 6 6 5 P-loop containing dynein motor region AAA_6 PF12774.7 PSC67589.1 - 5e-19 68.4 0.0 0.025 13.5 0.0 7.2 7 0 0 7 7 7 5 Hydrolytic ATP binding site of dynein motor region AAA_22 PF13401.6 PSC67589.1 - 1.4e-18 67.5 1.7 0.013 15.7 0.1 7.1 6 0 0 6 6 6 4 AAA domain Dynein_heavy PF03028.15 PSC67589.1 - 1.8e-16 60.3 0.0 0.096 12.8 0.0 6.7 7 0 0 7 7 6 4 Dynein heavy chain region D6 P-loop domain AAA_33 PF13671.6 PSC67589.1 - 3.4e-14 53.2 0.9 0.12 12.6 0.0 7.2 6 0 0 6 6 6 3 AAA domain TsaE PF02367.17 PSC67589.1 - 2.9e-12 46.7 7.6 0.0039 17.2 0.1 6.4 6 0 0 6 6 6 3 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 PSC67589.1 - 6.7e-12 45.4 0.4 0.016 14.9 0.0 5.6 6 0 0 6 6 5 3 Sigma-54 interaction domain AAA_18 PF13238.6 PSC67589.1 - 7.3e-12 46.0 0.8 0.24 12.0 0.0 6.3 6 0 0 6 6 5 1 AAA domain ABC_tran PF00005.27 PSC67589.1 - 2.2e-10 41.2 0.3 0.15 12.6 0.0 5.8 5 0 0 5 5 5 2 ABC transporter AAA_14 PF13173.6 PSC67589.1 - 1.3e-09 38.1 0.0 0.022 14.8 0.0 4.9 5 0 0 5 5 4 2 AAA domain AAA_29 PF13555.6 PSC67589.1 - 1.7e-09 37.3 1.5 3 7.7 0.0 6.2 6 0 0 6 6 6 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 PSC67589.1 - 6.8e-09 36.1 0.4 0.69 10.3 0.0 5.8 5 0 0 5 5 5 1 RNA helicase Zeta_toxin PF06414.12 PSC67589.1 - 3.3e-08 33.0 1.2 0.57 9.4 0.0 5.7 6 0 0 6 6 6 1 Zeta toxin T2SSE PF00437.20 PSC67589.1 - 5.5e-08 32.2 0.7 0.1 11.6 0.0 4.9 5 0 0 5 5 5 2 Type II/IV secretion system protein RuvB_N PF05496.12 PSC67589.1 - 1e-07 31.8 2.3 0.75 9.5 0.0 6.0 6 0 0 6 6 6 2 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 PSC67589.1 - 2.8e-07 30.0 0.4 0.56 9.3 0.1 5.1 5 0 0 5 5 5 2 Protein of unknown function (DUF815) AAA_19 PF13245.6 PSC67589.1 - 2.9e-07 30.9 2.6 0.94 9.8 0.1 6.0 5 0 0 5 5 4 1 AAA domain NACHT PF05729.12 PSC67589.1 - 1.6e-06 28.2 10.6 0.06 13.3 0.3 5.9 6 0 0 6 6 6 2 NACHT domain RsgA_GTPase PF03193.16 PSC67589.1 - 2.4e-06 27.6 0.2 0.5 10.3 0.1 4.7 5 0 0 5 5 5 1 RsgA GTPase Sigma54_activ_2 PF14532.6 PSC67589.1 - 1.4e-05 25.3 0.2 0.18 11.9 0.0 4.5 5 0 0 5 5 4 1 Sigma-54 interaction domain AAA_24 PF13479.6 PSC67589.1 - 1.7e-05 24.6 0.0 4 7.1 0.0 5.2 6 0 0 6 6 5 0 AAA domain IstB_IS21 PF01695.17 PSC67589.1 - 3e-05 23.8 2.8 0.6 9.8 0.0 5.3 5 0 0 5 5 5 1 IstB-like ATP binding protein PduV-EutP PF10662.9 PSC67589.1 - 9.2e-05 22.2 0.6 0.44 10.3 0.1 4.2 5 0 0 5 5 4 1 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 PSC67589.1 - 0.00014 22.3 11.9 0.0014 19.1 8.1 12.8 13 2 1 14 14 6 5 AAA ATPase domain AAA_28 PF13521.6 PSC67589.1 - 0.00019 21.7 17.5 1.9 8.7 0.0 7.3 7 0 0 7 7 5 1 AAA domain AAA_8 PF12780.7 PSC67589.1 - 0.00045 19.6 0.4 0.3 10.4 0.0 3.9 4 0 0 4 4 4 1 P-loop containing dynein motor region D4 MMR_HSR1 PF01926.23 PSC67589.1 - 0.00048 20.2 0.2 17 5.6 0.0 4.5 4 0 0 4 4 4 0 50S ribosome-binding GTPase AAA_11 PF13086.6 PSC67589.1 - 0.00057 19.8 0.9 37 4.0 0.0 5.7 6 0 0 6 6 5 0 AAA domain TIP49 PF06068.13 PSC67589.1 - 0.0012 18.2 3.3 2.8 7.1 0.1 4.2 4 0 0 4 4 4 1 TIP49 P-loop domain Rad17 PF03215.15 PSC67589.1 - 0.0022 17.9 1.2 8.6 6.2 0.0 5.1 6 0 0 6 6 6 0 Rad17 P-loop domain Roc PF08477.13 PSC67589.1 - 0.0026 18.0 1.6 1.9 8.7 0.1 4.6 5 0 0 5 5 5 1 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 PSC67589.1 - 0.0049 16.8 4.5 3.6 7.5 0.4 4.4 4 0 0 4 4 4 0 NTPase IPT PF01745.16 PSC67589.1 - 0.0058 16.1 0.5 0.93 8.8 0.0 3.2 3 0 0 3 3 3 1 Isopentenyl transferase ATPase PF06745.13 PSC67589.1 - 0.007 15.7 0.6 5.5 6.3 0.1 3.8 4 0 0 4 4 4 0 KaiC AAA_23 PF13476.6 PSC67589.1 - 0.011 16.3 10.5 8.7 6.8 0.0 6.2 6 0 0 6 6 5 0 AAA domain Mg_chelatase PF01078.21 PSC67589.1 - 0.013 14.9 18.3 1.3 8.4 0.3 8.0 9 1 0 10 10 8 0 Magnesium chelatase, subunit ChlI dNK PF01712.19 PSC67589.1 - 0.02 14.8 1.1 48 3.7 0.0 4.0 4 0 0 4 4 4 0 Deoxynucleoside kinase Viral_helicase1 PF01443.18 PSC67589.1 - 0.021 14.6 0.0 23 4.6 0.0 3.9 4 0 0 4 4 4 0 Viral (Superfamily 1) RNA helicase DEAD PF00270.29 PSC67589.1 - 0.022 14.5 0.1 21 4.8 0.0 3.7 4 0 0 4 4 3 0 DEAD/DEAH box helicase ATPase_2 PF01637.18 PSC67589.1 - 0.033 14.1 0.0 27 4.6 0.0 3.8 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea cobW PF02492.19 PSC67589.1 - 0.033 13.8 8.2 7.5 6.1 0.0 4.9 6 0 0 6 6 5 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 PSC67589.1 - 0.035 13.7 8.2 3.8 7.1 0.3 5.3 6 0 0 6 6 6 0 SRP54-type protein, GTPase domain TniB PF05621.11 PSC67589.1 - 0.04 13.3 0.0 7.7 5.9 0.0 4.0 6 0 0 6 6 4 0 Bacterial TniB protein Bac_DnaA PF00308.18 PSC67589.1 - 0.046 13.5 0.0 2.4 8.0 0.0 2.6 3 0 0 3 3 2 0 Bacterial dnaA protein ResIII PF04851.15 PSC67589.1 - 0.074 13.0 0.2 10 6.1 0.0 3.5 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit PhoH PF02562.16 PSC67589.1 - 0.085 12.3 0.1 16 4.8 0.0 3.5 4 0 0 4 4 3 0 PhoH-like protein DAP3 PF10236.9 PSC67589.1 - 0.087 12.0 2.3 6.6 5.8 0.1 3.5 4 0 0 4 4 3 0 Mitochondrial ribosomal death-associated protein 3 MCM PF00493.23 PSC67589.1 - 0.18 10.9 0.0 24 3.9 0.0 3.6 4 0 0 4 4 4 0 MCM P-loop domain SRPRB PF09439.10 PSC67589.1 - 0.21 11.0 0.3 26 4.2 0.0 3.1 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit UvrD-helicase PF00580.21 PSC67589.1 - 0.22 11.0 1.2 31 3.9 0.0 3.2 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain NB-ARC PF00931.22 PSC67589.1 - 2.1 7.5 3.7 1.9 7.6 0.1 2.6 4 0 0 4 4 2 0 NB-ARC domain CPT PF07931.12 PSC67589.1 - 2.5 7.9 11.2 3.4 7.5 0.1 5.6 6 1 0 6 6 5 0 Chloramphenicol phosphotransferase-like protein ATP_bind_1 PF03029.17 PSC67589.1 - 2.9 7.6 5.3 33 4.2 0.1 4.1 5 0 0 5 5 4 0 Conserved hypothetical ATP binding protein MutS_I PF01624.20 PSC67590.1 - 4.6e-14 52.6 0.0 9.5e-14 51.6 0.0 1.5 1 0 0 1 1 1 1 MutS domain I MutS_V PF00488.21 PSC67590.1 - 6.8e-10 39.3 0.0 1.1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 MutS domain V Dynamin_N PF00350.23 PSC67591.1 - 1e-28 100.5 0.0 1.5e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 PSC67591.1 - 5.3e-05 23.3 0.0 0.00021 21.4 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase Anoctamin PF04547.12 PSC67592.1 - 6.7e-06 25.2 0.5 5e-05 22.3 0.6 1.9 1 1 0 1 1 1 1 Calcium-activated chloride channel PHM7_cyt PF14703.6 PSC67592.1 - 1.5e-05 25.3 0.0 9.3e-05 22.7 0.0 2.1 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter RRM_1 PF00076.22 PSC67592.1 - 0.062 13.1 0.0 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_60s PF00428.19 PSC67593.1 - 0.012 16.1 1.2 0.012 16.1 1.2 2.0 2 0 0 2 2 2 0 60s Acidic ribosomal protein SWIRM-assoc_2 PF16496.5 PSC67593.1 - 0.035 13.0 0.5 0.038 12.9 0.5 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal RVT_2 PF07727.14 PSC67594.1 - 7.2e-184 608.6 0.0 3e-73 246.4 0.0 3.1 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PSC67594.1 - 3.1e-50 169.3 0.0 1.9e-23 82.9 0.0 3.0 2 0 0 2 2 2 2 Integrase core domain gag_pre-integrs PF13976.6 PSC67594.1 - 1.3e-20 73.0 0.0 9.3e-09 35.0 0.0 2.8 2 0 0 2 2 2 2 GAG-pre-integrase domain rve_3 PF13683.6 PSC67594.1 - 3.7e-11 42.6 0.1 0.00059 19.6 0.0 3.1 2 0 0 2 2 2 2 Integrase core domain Crr6 PF08847.11 PSC67594.1 - 3e-08 33.5 0.0 0.63 9.7 0.0 3.4 3 0 0 3 3 3 3 Chlororespiratory reduction 6 DAP_B PF07930.12 PSC67594.1 - 1.2e-05 25.4 0.3 4.8 7.1 0.0 3.4 3 0 0 3 3 3 3 D-aminopeptidase, domain B YdaS_antitoxin PF15943.5 PSC67594.1 - 0.00028 20.7 0.0 18 5.3 0.0 3.6 3 0 0 3 3 3 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DotU PF09850.9 PSC67594.1 - 0.025 14.3 0.0 11 5.7 0.0 2.5 2 0 0 2 2 2 0 Type VI secretion system protein DotU DUF1619 PF07773.11 PSC67594.1 - 0.078 12.9 0.0 18 5.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1619) DUF1659 PF07872.11 PSC67594.1 - 0.18 11.5 1.6 1e+02 2.7 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1659) CDP-OH_P_transf PF01066.21 PSC67595.1 - 0.029 15.2 0.9 0.052 14.3 0.9 1.5 1 1 0 1 1 1 0 CDP-alcohol phosphatidyltransferase RecR PF02132.15 PSC67595.1 - 0.15 11.6 3.6 0.28 10.8 3.6 1.5 1 0 0 1 1 1 0 RecR protein VIR_N PF15912.5 PSC67596.1 - 3.7 7.1 9.4 0.17 11.5 3.1 1.9 2 0 0 2 2 2 0 Virilizer, N-terminal VIR_N PF15912.5 PSC67597.1 - 5.2 6.6 9.6 0.17 11.5 3.1 1.8 2 0 0 2 2 2 0 Virilizer, N-terminal RVT_2 PF07727.14 PSC67599.1 - 1.6e-73 247.3 0.0 2.2e-73 246.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PSC67599.1 - 3.6e-24 85.2 0.0 1.1e-23 83.7 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 PSC67599.1 - 2.6e-09 36.8 0.0 5.7e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain Retrotran_gag_2 PF14223.6 PSC67599.1 - 1.1e-06 28.3 0.0 2.2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 PSC67599.1 - 4.4e-05 23.0 0.0 9e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) rve_3 PF13683.6 PSC67599.1 - 9.8e-05 22.1 0.0 0.00037 20.2 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_3 PF14244.6 PSC67599.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 PSC67599.1 - 0.15 11.8 2.0 0.29 10.9 2.0 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger Asp_protease_2 PF13650.6 PSC67599.1 - 0.15 12.7 0.0 0.66 10.6 0.0 2.1 2 0 0 2 2 2 0 Aspartyl protease zf-CCHC_3 PF13917.6 PSC67599.1 - 0.16 12.0 0.3 0.4 10.7 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle Crr6 PF08847.11 PSC67599.1 - 0.2 11.3 0.0 0.39 10.3 0.0 1.4 1 0 0 1 1 1 0 Chlororespiratory reduction 6 zf-CCHC_5 PF14787.6 PSC67599.1 - 0.32 10.7 2.5 0.92 9.3 2.5 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF4219 PF13961.6 PSC67600.1 - 1.1e-05 24.9 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_2 PF14223.6 PSC67600.1 - 0.0029 17.3 0.0 0.0044 16.7 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type Retrotran_gag_3 PF14244.6 PSC67600.1 - 0.026 14.3 0.0 0.056 13.3 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_3 PF13917.6 PSC67600.1 - 0.032 14.2 0.3 0.075 13.0 0.3 1.6 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 PSC67600.1 - 0.033 13.9 2.0 0.06 13.1 2.0 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_5 PF14787.6 PSC67600.1 - 0.096 12.4 2.5 0.18 11.5 2.5 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger KCNQ2_u3 PF16642.5 PSC67601.1 - 0.28 12.2 2.5 0.75 10.8 2.5 1.7 1 0 0 1 1 1 0 Unstructured region on Potassium channel subunit alpha KvLQT2 SVIP PF15811.5 PSC67601.1 - 2.8 8.4 16.2 1.1 9.7 11.4 2.8 2 0 0 2 2 2 0 Small VCP/p97-interacting protein rve PF00665.26 PSC67602.1 - 7.6e-19 68.1 0.0 1.8e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC67602.1 - 0.0065 16.2 0.0 0.019 14.7 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain DNA_ligase_A_N PF04675.14 PSC67603.1 - 9.6e-30 104.2 0.0 1.8e-29 103.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 PSC67603.1 - 2.1e-23 83.0 0.0 9.3e-23 80.9 0.0 2.1 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 PSC67603.1 - 2.4e-13 50.5 0.2 9.9e-12 45.3 0.0 3.1 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region FHA PF00498.26 PSC67603.1 - 9.2e-11 41.9 0.0 2.3e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 FHA domain zf-C3HC4_2 PF13923.6 PSC67603.1 - 3.2e-10 39.7 8.3 6e-10 38.8 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC67603.1 - 4e-09 36.7 7.1 8.8e-09 35.6 7.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PSC67603.1 - 1.5e-08 34.3 5.6 2.7e-08 33.5 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC67603.1 - 7.1e-07 29.0 6.0 7.1e-07 29.0 6.0 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) BRCT PF00533.26 PSC67603.1 - 1.8e-06 28.2 0.0 8.2e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PSC67603.1 - 5.2e-06 26.8 0.0 1.5e-05 25.3 0.0 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain zf-RING_UBOX PF13445.6 PSC67603.1 - 6e-06 26.2 5.0 1.8e-05 24.6 4.9 1.9 1 1 0 1 1 1 1 RING-type zinc-finger Yop-YscD_cpl PF16697.5 PSC67603.1 - 3.7e-05 24.0 0.0 0.00011 22.4 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Prok-RING_4 PF14447.6 PSC67603.1 - 3.7e-05 23.5 7.1 0.00055 19.8 7.4 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PSC67603.1 - 0.00014 21.7 5.8 0.00032 20.6 5.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain RNA_ligase PF09414.10 PSC67603.1 - 0.00026 21.3 0.0 0.00047 20.5 0.0 1.5 1 0 0 1 1 1 1 RNA ligase zf-C3HC4_4 PF15227.6 PSC67603.1 - 0.0087 16.2 7.6 0.02 15.0 7.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 PSC67603.1 - 0.011 16.0 7.6 0.026 14.8 7.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-WRNIP1_ubi PF18279.1 PSC67603.1 - 0.03 15.0 1.6 3 8.7 1.3 2.9 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-RING_6 PF14835.6 PSC67603.1 - 0.24 11.3 1.5 0.74 9.7 1.5 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 PSC67603.1 - 0.35 10.7 5.9 1.3 8.9 6.2 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DNA_ligase_A_N PF04675.14 PSC67604.1 - 9.6e-30 104.2 0.0 1.8e-29 103.3 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 PSC67604.1 - 2.2e-23 83.0 0.0 9.4e-23 80.9 0.0 2.1 1 1 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_C PF04679.15 PSC67604.1 - 2.5e-13 50.5 0.2 1e-11 45.3 0.0 3.1 3 0 0 3 3 3 1 ATP dependent DNA ligase C terminal region FHA PF00498.26 PSC67604.1 - 9.3e-11 41.9 0.0 2.4e-10 40.6 0.0 1.8 1 0 0 1 1 1 1 FHA domain zf-C3HC4_2 PF13923.6 PSC67604.1 - 3.2e-10 39.7 8.3 6e-10 38.8 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC67604.1 - 3.9e-09 36.7 7.1 8.9e-09 35.6 7.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PSC67604.1 - 1.5e-08 34.3 5.6 2.7e-08 33.5 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC67604.1 - 7.1e-07 29.0 6.0 7.1e-07 29.0 6.0 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) BRCT PF00533.26 PSC67604.1 - 1.8e-06 28.2 0.0 8.2e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PSC67604.1 - 5.2e-06 26.8 0.0 1.5e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain zf-RING_UBOX PF13445.6 PSC67604.1 - 5.9e-06 26.2 5.0 1.8e-05 24.6 4.9 1.9 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PSC67604.1 - 3.4e-05 23.6 7.1 0.00055 19.7 7.4 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Yop-YscD_cpl PF16697.5 PSC67604.1 - 3.7e-05 23.9 0.0 0.00011 22.4 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-RING_5 PF14634.6 PSC67604.1 - 0.00014 21.7 5.8 0.00032 20.6 5.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain RNA_ligase PF09414.10 PSC67604.1 - 0.00026 21.3 0.0 0.00047 20.5 0.0 1.5 1 0 0 1 1 1 1 RNA ligase zf-C3HC4_4 PF15227.6 PSC67604.1 - 0.0088 16.2 7.6 0.02 15.0 7.6 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 PSC67604.1 - 0.011 16.0 7.6 0.026 14.8 7.6 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-WRNIP1_ubi PF18279.1 PSC67604.1 - 0.03 14.9 1.6 3 8.7 1.3 2.9 2 0 0 2 2 2 0 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-RING_6 PF14835.6 PSC67604.1 - 0.24 11.3 1.5 0.75 9.7 1.5 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 PSC67604.1 - 0.35 10.7 5.9 1.3 8.8 6.2 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain UvdE PF03851.14 PSC67605.1 - 3.1e-63 213.6 0.0 4.1e-63 213.2 0.0 1.1 1 0 0 1 1 1 1 UV-endonuclease UvdE 4HBT PF03061.22 PSC67606.1 - 0.012 16.0 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily GDPD PF03009.17 PSC67608.1 - 1.1e-43 149.9 0.0 2.1e-43 148.9 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD PF03009.17 PSC67609.1 - 1.1e-43 149.8 0.0 2.2e-43 148.9 0.0 1.5 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 PSC67610.1 - 2.7e-25 88.8 1.3 2.1e-09 37.8 0.1 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC67610.1 - 5.4e-22 77.9 2.2 1.6e-09 38.1 0.0 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC67610.1 - 1e-21 76.7 4.8 1.6e-09 37.9 0.1 4.3 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 PSC67610.1 - 2e-21 75.4 6.6 2.4e-05 24.6 0.1 4.9 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 PSC67610.1 - 3.9e-16 57.5 2.1 0.00021 21.4 0.0 5.3 5 0 0 5 5 5 3 Ankyrin repeat U-box PF04564.15 PSC67610.1 - 3.3e-14 52.8 0.0 6.8e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 PSC67610.1 - 0.00041 20.1 0.0 0.00081 19.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 PSC67610.1 - 0.00046 20.3 0.0 0.00093 19.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein Methyltransf_28 PF02636.17 PSC67611.1 - 2.2e-33 116.0 0.0 3.6e-33 115.3 0.0 1.3 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_12 PF08242.12 PSC67611.1 - 0.00035 21.3 0.0 0.00082 20.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain P_proprotein PF01483.20 PSC67612.1 - 0.013 15.5 0.8 7.7 6.6 0.0 2.9 3 0 0 3 3 3 0 Proprotein convertase P-domain JAB PF01398.21 PSC67613.1 - 9.3e-33 112.7 0.0 1.7e-32 111.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 PSC67613.1 - 1.7e-11 44.5 0.1 3.4e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 PSC67613.1 - 1.8e-05 24.4 0.0 2.8e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Peptidase_C1 PF00112.23 PSC67614.1 - 1.2e-47 162.8 0.0 3e-47 161.5 0.0 1.7 1 0 0 1 1 1 1 Papain family cysteine protease ShK PF01549.24 PSC67614.1 - 7.7e-38 128.7 117.1 1.4e-07 31.9 10.9 9.5 8 2 0 8 8 8 8 ShK domain-like rve PF00665.26 PSC67614.1 - 1.3e-18 67.3 0.0 3.7e-18 65.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Inhibitor_I29 PF08246.12 PSC67614.1 - 8.3e-07 29.4 0.1 1.5e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) rve_3 PF13683.6 PSC67614.1 - 0.01 15.6 0.0 0.035 13.9 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain SKN1 PF03935.15 PSC67615.1 - 1.5e-79 267.8 5.1 6.8e-50 169.9 2.4 2.9 2 1 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 PSC67615.1 - 5.3e-09 35.8 0.0 3.3e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 PAN_1 PF00024.26 PSC67615.1 - 0.00012 21.9 1.1 0.00024 21.0 1.1 1.5 1 0 0 1 1 1 1 PAN domain PAN_4 PF14295.6 PSC67615.1 - 0.00075 19.4 1.2 0.00075 19.4 1.2 2.0 2 0 0 2 2 2 1 PAN domain COPI_assoc PF08507.10 PSC67616.1 - 0.061 13.4 1.9 0.13 12.3 1.8 1.6 1 1 0 1 1 1 0 COPI associated protein Bac_export_3 PF01313.19 PSC67616.1 - 0.58 10.1 2.1 5.9 6.9 0.1 2.8 3 0 0 3 3 3 0 Bacterial export proteins, family 3 Thioredoxin PF00085.20 PSC67617.1 - 1.8e-26 92.1 0.1 2.5e-26 91.6 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PSC67617.1 - 2.2e-08 34.5 0.0 8.7e-08 32.6 0.0 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PSC67617.1 - 6.6e-06 26.4 0.0 3.8e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 PSC67617.1 - 0.0015 18.4 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_7 PF13899.6 PSC67617.1 - 0.0021 18.2 0.1 0.0063 16.7 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.10 PSC67617.1 - 0.0022 17.7 0.1 0.02 14.6 0.2 2.0 1 1 1 2 2 2 1 Redoxin Thioredoxin_9 PF14595.6 PSC67617.1 - 0.013 15.3 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.6 PSC67617.1 - 0.023 14.7 0.1 0.059 13.4 0.1 1.8 1 1 0 1 1 1 0 Thioredoxin domain TraF PF13728.6 PSC67617.1 - 0.089 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein CPDase PF07823.11 PSC67618.1 - 5.1e-13 49.2 0.0 9.3e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein 2_5_RNA_ligase2 PF13563.6 PSC67618.1 - 1.6e-09 37.9 0.8 6.8e-09 35.8 0.0 2.3 2 0 0 2 2 2 1 2'-5' RNA ligase superfamily Nrap_D2 PF17403.2 PSC67618.1 - 0.00092 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain LigT_PEase PF02834.16 PSC67618.1 - 0.016 15.3 1.9 0.035 14.3 0.0 2.6 3 0 0 3 3 3 0 LigT like Phosphoesterase NTP_transf_2 PF01909.23 PSC67618.1 - 0.034 14.4 0.0 0.064 13.5 0.0 1.4 1 0 0 1 1 1 0 Nucleotidyltransferase domain DUF755 PF05501.11 PSC67618.1 - 2.4 8.4 4.6 4.5 7.6 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) WD40 PF00400.32 PSC67619.1 - 4e-23 81.3 19.4 2 9.4 0.3 12.8 12 0 0 12 12 12 9 WD domain, G-beta repeat Nup160 PF11715.8 PSC67619.1 - 2.8e-13 49.4 0.0 0.0023 16.6 0.0 5.3 6 0 0 6 6 6 3 Nucleoporin Nup120/160 EF-hand_8 PF13833.6 PSC67619.1 - 3e-09 36.6 0.0 8.1e-09 35.2 0.0 1.8 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 PSC67619.1 - 3.6e-08 33.7 0.0 1.1e-07 32.1 0.0 2.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 PSC67619.1 - 1.8e-07 30.2 3.1 0.0012 18.2 0.4 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PSC67619.1 - 3.7e-07 29.6 0.2 0.011 15.6 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PSC67619.1 - 1e-05 24.8 1.4 0.0021 17.5 0.2 2.4 2 0 0 2 2 2 2 EF hand vWF_A PF12450.8 PSC67619.1 - 0.098 12.6 0.0 15 5.6 0.0 3.1 3 0 0 3 3 3 0 von Willebrand factor DUF1860 PF08949.10 PSC67619.1 - 0.45 10.2 20.8 4.6 6.9 2.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1860) YGGT PF02325.17 PSC67620.1 - 0.005 17.2 0.1 0.012 16.1 0.1 1.6 1 0 0 1 1 1 1 YGGT family IKI3 PF04762.12 PSC67622.1 - 3.4e-157 525.1 0.0 1.5e-126 423.7 0.0 3.1 2 1 1 3 3 3 3 IKI3 family ANAPC4_WD40 PF12894.7 PSC67622.1 - 2.5e-07 30.9 0.0 0.013 15.8 0.0 3.9 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain SPATIAL PF15256.6 PSC67623.1 - 0.15 12.4 4.4 0.78 10.0 1.0 2.3 1 1 1 2 2 2 0 SPATIAL PGI PF00342.19 PSC67624.1 - 1.9e-206 686.4 0.0 2.3e-206 686.1 0.0 1.1 1 0 0 1 1 1 1 Phosphoglucose isomerase Ribosomal_S9 PF00380.19 PSC67624.1 - 2.5e-40 137.8 0.1 7.8e-40 136.2 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein S9/S16 LSM PF01423.22 PSC67625.1 - 3.2e-18 65.2 0.3 3.8e-18 64.9 0.3 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 PSC67625.1 - 0.00082 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 Hfq protein DUF3007 PF11460.8 PSC67626.1 - 7e-30 103.1 0.2 9.4e-30 102.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3007) PTCB-BRCT PF12738.7 PSC67627.1 - 1.1e-31 108.5 0.1 1.5e-13 50.5 0.0 3.9 4 0 0 4 4 4 3 twin BRCT domain BRCT PF00533.26 PSC67627.1 - 1e-21 77.1 0.0 8.5e-08 32.5 0.0 4.5 4 0 0 4 4 4 4 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PSC67627.1 - 2.7e-14 53.3 0.0 4e-05 23.9 0.0 4.6 5 0 0 5 5 5 2 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 PSC67627.1 - 2.1e-09 37.5 0.0 0.0045 17.2 0.0 4.1 4 0 0 4 4 4 3 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 PSC67627.1 - 0.0023 18.0 0.0 3.3 7.9 0.0 3.2 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain SelP_C PF04593.14 PSC67628.1 - 0.019 14.9 0.2 0.019 14.9 0.2 1.6 2 0 0 2 2 2 0 Selenoprotein P, C terminal region Dak2 PF02734.17 PSC67629.1 - 0.0033 17.3 0.6 0.0043 17.0 0.6 1.2 1 0 0 1 1 1 1 DAK2 domain CARM1 PF11531.8 PSC67629.1 - 0.11 12.7 0.1 0.23 11.7 0.1 1.5 1 0 0 1 1 1 0 Coactivator-associated arginine methyltransferase 1 N terminal WD40 PF00400.32 PSC67630.1 - 9.7e-05 23.1 11.6 1.1 10.2 0.1 6.8 7 0 0 7 7 7 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC67630.1 - 0.14 12.5 0.0 2.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4242 PF14026.6 PSC67630.1 - 0.14 12.3 0.2 2.9 8.1 0.4 3.0 3 1 0 3 3 3 0 Protein of unknown function (DUF4242) PGI PF00342.19 PSC67631.1 - 8.9e-207 687.5 0.0 1e-206 687.3 0.0 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase DUF1232 PF06803.12 PSC67632.1 - 2.8e-13 49.4 10.7 6.4e-13 48.3 10.7 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1232) AOX PF01786.17 PSC67633.1 - 2.9e-85 285.2 0.8 3.6e-85 284.9 0.8 1.1 1 0 0 1 1 1 1 Alternative oxidase ICMT PF04140.14 PSC67633.1 - 0.11 12.9 0.3 0.23 11.9 0.1 1.6 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family F5_F8_type_C PF00754.25 PSC67634.1 - 8.7e-07 29.1 11.7 0.097 12.8 0.2 5.9 5 1 1 6 6 6 5 F5/8 type C domain Peptidase_S26 PF10502.9 PSC67635.1 - 0.0014 18.4 0.0 0.57 10.0 0.0 3.1 2 1 1 3 3 3 2 Signal peptidase, peptidase S26 RVT_2 PF07727.14 PSC67636.1 - 8.8e-72 241.6 0.0 1.2e-71 241.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PSC67636.1 - 3.3e-23 82.1 0.0 4.8e-22 78.4 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 PSC67636.1 - 1.4e-09 37.7 0.0 2.9e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 PSC67636.1 - 5.7e-06 26.0 0.0 8.4e-05 22.3 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain zf-CCHC_5 PF14787.6 PSC67636.1 - 0.038 13.7 3.8 0.082 12.6 3.8 1.5 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 PSC67636.1 - 0.038 14.0 0.7 0.1 12.6 0.7 1.7 1 0 0 1 1 1 0 Zinc knuckle DDE_3 PF13358.6 PSC67636.1 - 0.044 13.5 0.0 0.097 12.4 0.0 1.5 1 0 0 1 1 1 0 DDE superfamily endonuclease zf-C2H2_10 PF16588.5 PSC67636.1 - 0.11 12.3 3.0 0.29 10.9 3.0 1.7 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 PSC67636.1 - 0.27 11.1 3.8 0.77 9.6 3.8 1.8 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC PF00098.23 PSC67636.1 - 0.44 10.7 5.8 0.18 11.9 3.0 1.9 2 0 0 2 2 2 0 Zinc knuckle Sugar_tr PF00083.24 PSC67638.1 - 2.5e-60 204.6 25.1 3.2e-60 204.3 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PSC67638.1 - 4.5e-17 62.0 25.3 4.5e-17 62.0 25.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily FapA PF03961.13 PSC67639.1 - 0.017 13.7 0.4 0.025 13.2 0.4 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A MscS_porin PF12795.7 PSC67639.1 - 0.021 14.4 25.2 0.018 14.6 4.9 2.5 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Sec2p PF06428.11 PSC67639.1 - 0.027 14.4 8.3 2.2 8.3 0.5 4.1 2 1 1 4 4 4 0 GDP/GTP exchange factor Sec2p DUF3584 PF12128.8 PSC67639.1 - 0.079 10.5 18.6 0.12 9.9 18.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Spc7 PF08317.11 PSC67639.1 - 0.11 11.4 14.8 0.17 10.8 12.9 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 PSC67639.1 - 0.11 12.5 8.1 1.2 9.2 4.8 2.3 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.6 PSC67639.1 - 0.27 10.9 5.0 0.76 9.5 2.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4201) GAS PF13851.6 PSC67639.1 - 0.78 9.0 9.2 5 6.4 0.9 3.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Golgin_A5 PF09787.9 PSC67639.1 - 0.92 8.9 8.2 1.6 8.1 5.8 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 AAA_13 PF13166.6 PSC67639.1 - 1.4 7.5 7.6 2.4 6.7 7.6 1.4 1 0 0 1 1 1 0 AAA domain Sec8_exocyst PF04048.14 PSC67639.1 - 2 8.3 6.0 2.2 8.2 0.1 3.0 2 1 2 4 4 4 0 Sec8 exocyst complex component specific domain Filament PF00038.21 PSC67639.1 - 4.6 6.7 12.1 26 4.3 9.0 2.7 1 1 1 2 2 2 0 Intermediate filament protein TMPIT PF07851.13 PSC67639.1 - 5 6.3 5.1 10 5.3 0.3 2.1 1 1 1 2 2 2 0 TMPIT-like protein GREB1 PF15782.5 PSC67639.1 - 5.8 3.9 8.5 7.2 3.6 8.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Fez1 PF06818.15 PSC67639.1 - 7.5 7.0 12.4 37 4.7 6.1 2.2 1 1 1 2 2 2 0 Fez1 TRADD_N PF09034.10 PSC67640.1 - 0.59 10.2 5.5 19 5.3 0.5 3.1 2 1 1 3 3 3 0 TRADD, N-terminal domain SPATIAL PF15256.6 PSC67640.1 - 2.7 8.3 9.3 3.9 7.8 1.7 2.4 1 1 1 2 2 2 0 SPATIAL Form_Nir_trans PF01226.17 PSC67641.1 - 2.5e-70 236.5 14.3 3.4e-70 236.1 14.3 1.1 1 0 0 1 1 1 1 Formate/nitrite transporter EAP30 PF04157.16 PSC67642.1 - 1e-69 234.4 0.0 1.7e-69 233.7 0.0 1.3 1 0 0 1 1 1 1 EAP30/Vps36 family Glyco_hydro_46 PF01374.18 PSC67642.1 - 1.7e-42 145.4 0.0 1.3e-21 77.3 0.0 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 46 AbiEi_4 PF13338.6 PSC67642.1 - 0.021 15.0 0.3 0.072 13.3 0.1 2.2 2 0 0 2 2 2 0 Transcriptional regulator, AbiEi antitoxin zf-GRF PF06839.12 PSC67643.1 - 0.036 14.2 1.7 0.06 13.5 1.7 1.4 1 0 0 1 1 1 0 GRF zinc finger SH2 PF00017.24 PSC67644.1 - 1.7e-05 24.8 0.0 4.6e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 SH2 domain LNP1 PF15419.6 PSC67644.1 - 0.15 12.3 6.0 0.31 11.3 6.0 1.5 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 ATP_synt_H PF05493.13 PSC67645.1 - 8.9e-21 74.1 3.3 9.7e-21 74.0 3.3 1.0 1 0 0 1 1 1 1 ATP synthase subunit H DUF3392 PF11872.8 PSC67645.1 - 0.0037 17.5 1.7 0.0045 17.2 1.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3392) DUF1345 PF07077.11 PSC67645.1 - 0.0058 16.3 0.5 0.0064 16.2 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1345) ARL6IP6 PF15062.6 PSC67645.1 - 0.08 13.1 0.2 0.11 12.6 0.2 1.3 1 1 0 1 1 1 0 Haemopoietic lineage transmembrane helix Ribosomal_L28e PF01778.17 PSC67646.1 - 1.6e-38 132.0 1.8 1.6e-38 132.0 1.8 1.7 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 PSC67646.1 - 1e-15 58.2 49.8 3.8e-15 56.3 43.3 3.2 2 1 0 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 PSC67646.1 - 3.4e-05 23.4 15.9 4.4e-05 23.0 15.9 1.2 1 0 0 1 1 1 1 BUD22 DUF688 PF05097.12 PSC67646.1 - 0.095 11.9 3.5 0.14 11.3 3.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF688) Nop14 PF04147.12 PSC67646.1 - 0.14 10.3 23.9 0.2 9.8 23.9 1.2 1 0 0 1 1 1 0 Nop14-like family TFIIA PF03153.13 PSC67646.1 - 0.15 12.0 10.9 0.2 11.6 10.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit XRN_M PF17846.1 PSC67646.1 - 1.8 7.4 9.4 2.7 6.8 9.4 1.2 1 0 0 1 1 1 0 Xrn1 helical domain Exonuc_VII_L PF02601.15 PSC67646.1 - 4 6.9 6.3 5.7 6.4 6.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 PSC67646.1 - 5.1 6.4 10.1 8.8 5.6 10.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sporozoite_P67 PF05642.11 PSC67646.1 - 5.8 4.9 7.1 8 4.4 7.1 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TIM PF00121.18 PSC67648.1 - 1.6e-81 273.3 0.0 5.6e-81 271.5 0.0 1.7 1 1 0 1 1 1 1 Triosephosphate isomerase Peptidase_M24 PF00557.24 PSC67649.1 - 5.5e-22 78.5 1.5 9.9e-22 77.7 1.3 1.5 1 1 0 1 1 1 1 Metallopeptidase family M24 DAHP_synth_1 PF00793.20 PSC67650.1 - 5.5e-57 192.7 0.0 6.9e-57 192.4 0.0 1.0 1 0 0 1 1 1 1 DAHP synthetase I family SNF2_N PF00176.23 PSC67651.1 - 1.6e-50 171.8 0.0 3.3e-50 170.8 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC67651.1 - 3.9e-14 52.9 0.0 9.4e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC67651.1 - 3.4e-06 27.1 0.0 6.2e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 PSC67651.1 - 0.012 14.8 0.0 0.031 13.5 0.0 1.6 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 DUF2075 PF09848.9 PSC67651.1 - 0.014 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Phosphoprotein PF00922.17 PSC67651.1 - 0.44 10.1 2.5 0.73 9.4 2.5 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Peptidase_M41 PF01434.18 PSC67652.1 - 9.7e-65 218.0 0.0 1.7e-64 217.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 PSC67652.1 - 2.8e-46 157.2 0.0 5.4e-46 156.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PSC67652.1 - 2.7e-13 49.5 1.0 6e-13 48.4 0.1 2.1 2 0 0 2 2 2 1 AAA+ lid domain TIP49 PF06068.13 PSC67652.1 - 1.3e-05 24.6 0.1 3e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 PSC67652.1 - 2.7e-05 24.2 0.0 0.00011 22.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) FtsH_ext PF06480.15 PSC67652.1 - 5e-05 23.6 0.0 0.00013 22.3 0.0 1.7 1 0 0 1 1 1 1 FtsH Extracellular RuvB_N PF05496.12 PSC67652.1 - 6e-05 22.8 0.0 0.00039 20.2 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PSC67652.1 - 0.00018 21.9 0.1 0.01 16.2 0.2 2.7 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PSC67652.1 - 0.00033 20.9 0.1 0.11 12.8 0.1 3.0 1 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 PSC67652.1 - 0.00069 19.8 0.0 0.003 17.7 0.0 2.1 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 PSC67652.1 - 0.00089 19.7 0.4 0.004 17.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 PSC67652.1 - 0.0022 17.8 0.0 0.0039 16.9 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 PSC67652.1 - 0.0046 16.4 0.0 0.0089 15.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 PSC67652.1 - 0.0046 17.1 0.4 0.015 15.5 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 PSC67652.1 - 0.015 15.8 0.1 0.068 13.7 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PSC67652.1 - 0.025 14.8 0.0 0.056 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PSC67652.1 - 0.051 13.1 0.2 0.22 11.0 0.2 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 PSC67652.1 - 0.051 13.6 0.0 0.13 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 PSC67652.1 - 0.056 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 PSC67652.1 - 0.069 12.8 0.0 0.23 11.1 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 PSC67652.1 - 0.078 13.5 0.1 0.24 11.9 0.1 1.8 1 0 0 1 1 1 0 ABC transporter ATPase PF06745.13 PSC67652.1 - 0.086 12.2 2.1 0.87 8.9 0.0 2.8 3 0 0 3 3 3 0 KaiC AAA_25 PF13481.6 PSC67652.1 - 0.096 12.3 1.0 0.65 9.5 0.3 2.3 1 1 0 2 2 2 0 AAA domain CPT PF07931.12 PSC67652.1 - 0.1 12.4 0.0 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Zeta_toxin PF06414.12 PSC67652.1 - 0.14 11.4 0.5 0.53 9.5 0.4 2.0 1 1 1 2 2 2 0 Zeta toxin DUF4110 PF13422.6 PSC67652.1 - 0.16 12.0 0.2 0.45 10.6 0.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) AAA_24 PF13479.6 PSC67652.1 - 0.2 11.4 0.8 0.54 10.0 0.1 2.0 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 PSC67653.1 - 1.4e-60 205.3 0.4 2.6e-60 204.4 0.4 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 PSC67653.1 - 1.8e-53 181.1 0.0 2.6e-53 180.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PSC67653.1 - 2.4e-10 40.5 1.9 2.3e-08 34.0 1.9 3.2 1 1 0 1 1 1 1 AAA domain R3H PF01424.22 PSC67653.1 - 1.7e-08 34.3 0.0 4.8e-08 32.9 0.0 1.7 1 0 0 1 1 1 1 R3H domain AAA_19 PF13245.6 PSC67653.1 - 4.4e-08 33.6 0.6 1.2e-06 29.0 0.1 2.8 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 PSC67653.1 - 5.7e-07 29.5 0.1 0.58 9.9 0.0 3.2 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 PSC67653.1 - 0.00096 18.5 0.6 0.038 13.2 0.6 2.5 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA PF00004.29 PSC67653.1 - 0.0017 18.8 0.1 0.0043 17.5 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 PSC67653.1 - 0.0041 16.7 1.8 0.027 14.0 1.8 2.4 1 1 0 1 1 1 1 AAA domain UvrD-helicase PF00580.21 PSC67653.1 - 0.0045 16.5 0.0 0.015 14.8 0.0 1.8 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 PSC67653.1 - 0.0051 17.1 2.6 0.55 10.5 2.6 2.9 1 1 0 1 1 1 1 AAA domain Helicase_RecD PF05127.14 PSC67653.1 - 0.0063 16.4 2.8 0.096 12.5 0.8 2.9 2 1 0 2 2 2 1 Helicase DHHA1 PF02272.19 PSC67653.1 - 0.0065 16.9 3.6 0.0083 16.5 1.1 2.5 2 0 0 2 2 2 1 DHHA1 domain PIF1 PF05970.14 PSC67653.1 - 0.012 14.8 0.0 3.4 6.7 0.0 2.3 1 1 0 2 2 2 0 PIF1-like helicase DnaB_C PF03796.15 PSC67653.1 - 0.018 14.4 0.1 0.03 13.7 0.1 1.3 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_33 PF13671.6 PSC67653.1 - 0.018 15.2 0.1 0.078 13.1 0.1 2.2 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 PSC67653.1 - 0.021 14.6 1.0 0.22 11.3 1.0 2.3 1 1 0 1 1 1 0 DEAD/DEAH box helicase UvrD_C_2 PF13538.6 PSC67653.1 - 0.023 14.5 0.1 0.078 12.8 0.1 1.9 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain RuvB_N PF05496.12 PSC67653.1 - 0.055 13.2 0.2 0.2 11.4 0.0 1.9 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 PSC67653.1 - 0.065 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 PSC67653.1 - 0.091 13.3 0.0 0.29 11.7 0.0 1.9 1 1 0 1 1 1 0 ABC transporter PhoH PF02562.16 PSC67653.1 - 0.1 12.1 0.0 0.44 10.0 0.0 2.1 1 1 0 1 1 1 0 PhoH-like protein AAA_16 PF13191.6 PSC67653.1 - 0.12 12.7 5.1 0.05 14.0 1.4 2.4 2 1 0 2 2 1 0 AAA ATPase domain NTPase_1 PF03266.15 PSC67653.1 - 0.15 11.9 0.6 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 NTPase DEAD PF00270.29 PSC67654.1 - 4.1e-19 69.0 0.0 8.6e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC67654.1 - 2e-14 53.9 0.0 5.2e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HRDC PF00570.23 PSC67654.1 - 1.3e-10 41.1 0.3 3.4e-10 39.7 0.3 1.7 1 0 0 1 1 1 1 HRDC domain RecQ_Zn_bind PF16124.5 PSC67654.1 - 1.3e-06 29.0 1.5 1.3e-06 29.0 1.5 2.3 3 0 0 3 3 1 1 RecQ zinc-binding RQC PF09382.10 PSC67654.1 - 4.1e-06 26.5 0.0 1.7e-05 24.6 0.0 2.1 1 1 0 1 1 1 1 RQC domain DUF572 PF04502.13 PSC67654.1 - 0.072 12.7 8.7 0.11 12.0 8.7 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) RR_TM4-6 PF06459.12 PSC67654.1 - 1.7 8.4 12.0 2.8 7.7 12.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ORC6 PF05460.13 PSC67654.1 - 6.8 5.9 15.4 12 5.0 15.4 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Suf PF05843.14 PSC67654.1 - 7.5 6.4 17.4 13 5.6 17.4 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1387 PF07139.11 PSC67654.1 - 7.7 6.2 11.1 15 5.2 11.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Hid1 PF12722.7 PSC67654.1 - 9.6 4.2 9.8 13 3.7 9.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ribosomal_S3Ae PF01015.18 PSC67655.1 - 1.9e-96 321.5 2.2 2.3e-96 321.2 2.2 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family SUI1 PF01253.22 PSC67655.1 - 0.035 14.6 0.1 0.77 10.3 0.0 2.7 2 0 0 2 2 2 0 Translation initiation factor SUI1 Abhydro_lipase PF04083.16 PSC67655.1 - 0.086 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region DPBB_1 PF03330.18 PSC67656.1 - 5e-23 81.2 2.2 1.2e-10 41.6 0.2 3.1 2 0 0 2 2 2 2 Lytic transglycolase Peptidase_M4 PF01447.18 PSC67656.1 - 0.084 13.4 0.1 0.54 10.8 0.0 2.0 2 0 0 2 2 2 0 Thermolysin metallopeptidase, catalytic domain ShK PF01549.24 PSC67656.1 - 2.6 8.6 132.3 0.025 15.1 3.1 10.1 11 0 0 11 11 11 0 ShK domain-like Autophagy_N PF03986.13 PSC67657.1 - 5.5e-41 139.7 0.0 8.3e-41 139.1 0.0 1.3 1 0 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 PSC67657.1 - 1.5e-17 63.9 0.0 2.6e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 PSC67657.1 - 3.4e-14 52.1 0.4 6.7e-14 51.1 0.4 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal Methyltransf_25 PF13649.6 PSC67658.1 - 2.9e-12 47.1 0.0 7.2e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Aa_trans PF01490.18 PSC67658.1 - 4.1e-12 45.5 20.2 6.3e-12 44.9 20.2 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Methyltransf_11 PF08241.12 PSC67658.1 - 4.8e-11 43.2 0.0 1.1e-10 42.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC67658.1 - 7.8e-09 35.5 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC67658.1 - 5.5e-06 27.0 0.0 1.2e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC67658.1 - 0.00025 20.9 0.0 0.00045 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC67658.1 - 0.00067 19.1 0.0 0.0011 18.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.11 PSC67658.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) UPF0020 PF01170.18 PSC67658.1 - 0.1 12.2 0.0 0.9 9.2 0.0 2.0 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 Aa_trans PF01490.18 PSC67659.1 - 9.2e-14 51.0 20.2 1.4e-13 50.3 20.2 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Methyltransf_25 PF13649.6 PSC67659.1 - 2.8e-12 47.2 0.0 7.2e-12 45.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC67659.1 - 4.8e-11 43.1 0.0 1.1e-10 42.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC67659.1 - 7.7e-09 35.5 0.0 1.4e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC67659.1 - 5.4e-06 27.1 0.0 1.2e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC67659.1 - 0.00025 20.9 0.0 0.00044 20.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC67659.1 - 0.00063 19.2 0.0 0.0011 18.4 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family UPF0020 PF01170.18 PSC67659.1 - 0.1 12.2 0.0 0.9 9.2 0.0 2.0 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 TPMT PF05724.11 PSC67659.1 - 0.1 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Yos1 PF08571.10 PSC67660.1 - 5.3e-24 84.3 0.1 5.8e-24 84.2 0.1 1.0 1 0 0 1 1 1 1 Yos1-like DUF179 PF02622.15 PSC67661.1 - 1e-15 58.1 0.0 1.6e-10 41.2 0.0 2.7 2 0 0 2 2 2 2 Uncharacterized ACR, COG1678 Velvet PF11754.8 PSC67661.1 - 0.0031 17.5 1.0 0.022 14.7 0.2 2.1 2 0 0 2 2 2 1 Velvet factor DDHD PF02862.17 PSC67661.1 - 0.0049 17.0 0.7 0.0049 17.0 0.7 1.7 2 0 0 2 2 2 1 DDHD domain STAC2_u1 PF16664.5 PSC67661.1 - 0.0063 17.0 2.7 0.018 15.5 2.7 1.7 1 0 0 1 1 1 1 Unstructured on SH3 and cysteine-rich domain-containing protein 2 PepSY_TM PF03929.16 PSC67661.1 - 0.082 12.6 4.6 0.35 10.5 1.0 2.6 2 0 0 2 2 2 0 PepSY-associated TM region CLN3 PF02487.17 PSC67661.1 - 0.34 9.9 2.5 0.55 9.2 2.5 1.2 1 0 0 1 1 1 0 CLN3 protein SpoIIP PF07454.11 PSC67661.1 - 0.71 9.3 12.2 0.017 14.6 5.8 1.4 2 0 0 2 2 1 0 Stage II sporulation protein P (SpoIIP) Ndc1_Nup PF09531.10 PSC67661.1 - 0.75 8.4 7.7 0.65 8.6 3.7 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup DUF4228 PF14009.6 PSC67661.1 - 1.5 9.2 11.5 0.15 12.5 1.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4228) MDM10 PF12519.8 PSC67661.1 - 2.5 6.9 4.9 3.8 6.3 4.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 DUF2828 PF11443.8 PSC67661.1 - 2.6 6.0 9.7 4.1 5.4 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) GREB1 PF15782.5 PSC67661.1 - 2.9 4.9 6.9 4 4.4 6.9 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pex14_N PF04695.13 PSC67661.1 - 2.9 8.5 27.3 5 7.8 17.2 2.6 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 PSC67661.1 - 3.5 6.3 15.0 0.2 10.4 9.7 1.5 2 0 0 2 2 2 0 Presenilin SLC12 PF03522.15 PSC67661.1 - 3.7 6.5 8.4 6 5.8 8.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 SART-1 PF03343.13 PSC67661.1 - 4.6 5.7 16.0 9.9 4.6 16.0 1.4 1 0 0 1 1 1 0 SART-1 family BAF1_ABF1 PF04684.13 PSC67661.1 - 4.7 6.2 11.3 8.6 5.3 11.3 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Neur_chan_memb PF02932.16 PSC67661.1 - 5.2 7.1 8.3 0.9 9.6 4.0 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region DUF5327 PF17261.2 PSC67661.1 - 5.2 7.9 20.3 3.4 8.5 11.8 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5327) CPSF100_C PF13299.6 PSC67661.1 - 6 7.0 14.3 0.17 12.1 7.2 2.0 3 0 0 3 3 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF913 PF06025.12 PSC67661.1 - 7.5 5.4 6.7 17 4.2 6.7 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 PSC67661.1 - 9.8 4.8 10.4 15 4.2 10.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Pollen_allerg_1 PF01357.21 PSC67662.1 - 1.1e-34 118.3 1.3 2.4e-16 59.5 0.2 2.5 2 0 0 2 2 2 2 Pollen allergen DPBB_1 PF03330.18 PSC67662.1 - 1.3e-28 99.1 0.5 5.1e-13 49.1 0.1 2.7 2 0 0 2 2 2 2 Lytic transglycolase zf-ribbon_3 PF13248.6 PSC67662.1 - 0.0036 16.7 1.3 4 7.0 0.1 3.3 2 0 0 2 2 2 2 zinc-ribbon domain Redoxin PF08534.10 PSC67662.1 - 0.046 13.4 1.0 8.7 6.0 0.1 2.8 2 0 0 2 2 2 0 Redoxin zf_CopZ PF18423.1 PSC67662.1 - 0.064 13.2 0.4 16 5.5 0.0 2.4 2 0 0 2 2 2 0 Zinc binding domain zf-ZPR1 PF03367.13 PSC67662.1 - 0.09 12.6 0.1 18 5.1 0.0 2.2 2 0 0 2 2 2 0 ZPR1 zinc-finger domain Transformer PF06495.11 PSC67662.1 - 0.19 11.8 2.1 6.6 6.8 0.2 2.2 2 0 0 2 2 2 0 Fruit fly transformer protein UPF0547 PF10571.9 PSC67662.1 - 0.28 11.3 4.6 16 5.7 0.4 3.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 IGPS PF00218.21 PSC67663.1 - 9.5e-77 257.6 0.0 1.2e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 Indole-3-glycerol phosphate synthase PUF PF00806.19 PSC67664.1 - 7.6e-58 189.1 2.7 2.2e-09 36.5 0.1 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat HSP20 PF00011.21 PSC67664.1 - 7e-08 32.6 0.0 0.00071 19.7 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PSC67664.1 - 0.00069 19.1 0.1 0.0036 16.8 0.0 2.2 2 1 0 2 2 2 1 HSP20-like domain found in ArsA PUF PF00806.19 PSC67665.1 - 7.7e-58 189.1 2.7 2.2e-09 36.5 0.1 8.3 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat HSP20 PF00011.21 PSC67665.1 - 7e-08 32.6 0.0 0.00072 19.7 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PSC67665.1 - 0.00069 19.1 0.1 0.0036 16.8 0.0 2.2 2 1 0 2 2 2 1 HSP20-like domain found in ArsA ClpS PF02617.17 PSC67666.1 - 2.8e-16 59.1 0.2 2.8e-16 59.1 0.2 1.8 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS SNase PF00565.17 PSC67667.1 - 4.2e-17 62.6 0.0 5.9e-17 62.1 0.0 1.2 1 0 0 1 1 1 1 Staphylococcal nuclease homologue RskA PF10099.9 PSC67667.1 - 1.2 9.4 17.0 2.9 8.1 5.1 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF4667 PF15700.5 PSC67668.1 - 0.0089 16.2 1.0 0.0089 16.2 1.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4667) SSP160 PF06933.11 PSC67668.1 - 2.5 6.2 20.6 1.8 6.7 0.1 2.3 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Ribosomal_L22e PF01776.17 PSC67669.1 - 4.4e-46 155.7 4.2 5.5e-46 155.5 4.2 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family AdoMet_Synthase PF01941.19 PSC67669.1 - 0.01 14.7 1.2 0.012 14.4 1.2 1.0 1 0 0 1 1 1 0 S-adenosylmethionine synthetase (AdoMet synthetase) DPBB_1 PF03330.18 PSC67670.1 - 1.5e-20 73.3 2.5 9.1e-12 45.1 0.3 3.9 5 0 0 5 5 5 2 Lytic transglycolase LOR PF04525.12 PSC67671.1 - 3e-25 88.9 0.0 3.6e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 LURP-one-related CS PF04969.16 PSC67672.1 - 2.7e-06 28.3 0.0 4.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 PSC67672.1 - 7.8e-06 25.5 5.2 0.024 14.4 0.6 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 PSC67672.1 - 0.001 19.1 2.0 0.072 13.3 0.2 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 PSC67672.1 - 0.0012 18.8 12.7 0.034 14.3 1.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 PSC67672.1 - 5.8 7.2 10.9 0.69 10.1 0.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DPBB_1 PF03330.18 PSC67673.1 - 1.9e-23 82.5 2.0 9.4e-11 41.8 0.2 3.1 2 0 0 2 2 2 2 Lytic transglycolase ShK PF01549.24 PSC67673.1 - 0.0075 16.8 111.9 0.051 14.1 5.8 9.2 10 0 0 10 10 10 7 ShK domain-like HARE-HTH PF05066.13 PSC67674.1 - 0.00052 20.4 0.0 0.00092 19.6 0.0 1.4 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain ubiquitin PF00240.23 PSC67675.1 - 4.4e-15 55.2 0.0 7.5e-15 54.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family YukD PF08817.10 PSC67675.1 - 0.035 14.8 0.2 0.17 12.6 0.2 2.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Rad60-SLD PF11976.8 PSC67675.1 - 0.064 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like TFIIA PF03153.13 PSC67675.1 - 0.34 10.9 13.9 1.6 8.7 2.7 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Form_Nir_trans PF01226.17 PSC67676.1 - 1e-52 178.8 15.8 1.9e-51 174.7 12.8 2.0 1 1 1 2 2 2 2 Formate/nitrite transporter LapA_dom PF06305.11 PSC67676.1 - 0.44 10.4 1.9 0.72 9.7 0.0 2.3 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain RabGAP-TBC PF00566.18 PSC67678.1 - 2.2e-37 128.8 0.0 1.6e-35 122.7 0.0 2.0 2 0 0 2 2 2 2 Rab-GTPase-TBC domain MBOAT PF03062.19 PSC67679.1 - 9.9e-13 48.2 6.6 8.7e-12 45.0 6.6 2.0 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family GDPD PF03009.17 PSC67680.1 - 4.7e-06 26.5 0.0 1.7e-05 24.7 0.0 1.8 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD PF03009.17 PSC67681.1 - 4.9e-06 26.4 0.0 1.8e-05 24.6 0.0 1.8 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD PF03009.17 PSC67682.1 - 6.6e-06 26.0 0.0 3.1e-05 23.8 0.0 1.9 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family API5 PF05918.11 PSC67683.1 - 9.8 4.8 7.7 0.71 8.6 2.0 1.7 2 0 0 2 2 2 0 Apoptosis inhibitory protein 5 (API5) PCMT PF01135.19 PSC67684.1 - 4.7e-68 229.1 0.0 6e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 PSC67684.1 - 0.00011 22.8 0.0 0.00025 21.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC67684.1 - 0.00034 20.5 0.0 0.00059 19.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 PSC67684.1 - 0.00097 19.1 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC67684.1 - 0.00098 19.0 0.0 0.0023 17.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PSC67684.1 - 0.0031 17.1 0.0 0.008 15.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.12 PSC67684.1 - 0.0083 16.7 0.0 0.027 15.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PSC67684.1 - 0.055 12.9 0.0 0.085 12.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_24 PF13578.6 PSC67684.1 - 0.078 14.0 0.0 1.7 9.7 0.0 2.5 1 1 1 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 PSC67684.1 - 0.15 11.4 0.0 0.23 10.8 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family MetW PF07021.12 PSC67684.1 - 0.16 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RrnaAD PF00398.20 PSC67684.1 - 0.21 10.6 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PTPlike_phytase PF14566.6 PSC67685.1 - 2.6e-125 414.2 0.0 1.6e-53 181.0 0.0 4.2 4 0 0 4 4 4 4 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 PSC67685.1 - 0.03 14.3 0.0 1.8 8.5 0.0 2.7 2 0 0 2 2 2 0 Tyrosine phosphatase family TRAM_LAG1_CLN8 PF03798.16 PSC67686.1 - 1.6e-29 103.1 7.3 1.9e-29 102.9 7.3 1.1 1 0 0 1 1 1 1 TLC domain VOMI PF03762.17 PSC67687.1 - 2.5e-25 89.6 2.2 4.7e-25 88.7 2.2 1.4 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) F5_F8_type_C PF00754.25 PSC67687.1 - 3.6e-06 27.1 0.5 0.0011 19.1 0.0 3.1 4 0 0 4 4 4 2 F5/8 type C domain Aldose_epim PF01263.20 PSC67689.1 - 1e-37 130.1 0.0 4e-36 124.9 0.0 2.0 1 1 0 1 1 1 1 Aldose 1-epimerase Ank_2 PF12796.7 PSC67690.1 - 2.4e-17 63.3 0.1 1.6e-09 38.2 0.0 3.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC67690.1 - 8.9e-16 57.8 1.6 2.8e-06 27.5 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC67690.1 - 8.2e-12 45.4 0.5 0.011 16.3 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC67690.1 - 4.8e-11 41.9 0.2 0.057 14.0 0.0 6.2 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 PSC67690.1 - 6.6e-09 35.8 7.5 0.012 16.0 0.2 5.5 5 0 0 5 5 5 2 Ankyrin repeat PP2C PF00481.21 PSC67691.1 - 1.4e-75 254.3 0.0 6.3e-61 206.3 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 PSC67691.1 - 4e-09 36.4 0.5 1.4e-06 28.2 0.0 2.5 2 1 0 2 2 2 2 Protein phosphatase 2C SpoIIE PF07228.12 PSC67691.1 - 9.7e-07 28.9 0.1 1.8e-05 24.8 0.1 2.4 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Glyco_hydro_35 PF01301.19 PSC67692.1 - 4.6e-104 348.4 0.0 5.7e-104 348.1 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Glyco_hydro_42 PF02449.15 PSC67692.1 - 2e-08 34.0 1.0 3.1e-08 33.4 1.0 1.2 1 0 0 1 1 1 1 Beta-galactosidase BetaGal_dom4_5 PF13364.6 PSC67692.1 - 6.9e-08 33.1 0.0 0.0021 18.6 0.0 2.9 3 0 0 3 3 3 2 Beta-galactosidase jelly roll domain Exo_endo_phos PF03372.23 PSC67693.1 - 3.3e-10 39.9 0.0 9.5e-10 38.4 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UCH PF00443.29 PSC67694.1 - 2.9e-12 46.6 0.0 4.9e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PSC67694.1 - 0.0027 17.3 0.0 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-CCCH PF00642.24 PSC67694.1 - 0.0035 17.2 13.6 0.087 12.8 0.1 3.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PSC67694.1 - 0.018 15.1 15.2 0.14 12.3 0.2 3.8 3 0 0 3 3 3 0 Zinc finger domain DUF4366 PF14283.6 PSC67694.1 - 0.63 10.1 5.7 11 6.0 0.6 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) UCH PF00443.29 PSC67695.1 - 2.9e-12 46.6 0.0 5e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PSC67695.1 - 0.0027 17.3 0.0 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-CCCH PF00642.24 PSC67695.1 - 0.0035 17.2 13.6 0.087 12.8 0.1 3.7 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PSC67695.1 - 0.018 15.1 15.2 0.14 12.3 0.2 3.8 3 0 0 3 3 3 0 Zinc finger domain DUF4366 PF14283.6 PSC67695.1 - 0.65 10.0 5.7 11 6.0 0.6 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4366) Ank_2 PF12796.7 PSC67696.1 - 5.3e-17 62.2 1.1 1.3e-10 41.7 0.1 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC67696.1 - 1.1e-13 51.0 1.0 7.1e-08 32.6 0.2 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) U-box PF04564.15 PSC67696.1 - 5e-10 39.4 0.0 8.4e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 U-box domain Ank_3 PF13606.6 PSC67696.1 - 2.6e-09 36.5 0.6 0.0054 17.1 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 PSC67696.1 - 4.6e-08 33.5 3.0 2.8e-05 24.6 0.3 2.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 PSC67696.1 - 2e-07 31.1 5.3 0.00024 21.4 0.6 3.1 3 0 0 3 3 3 2 Ankyrin repeat zf-Nse PF11789.8 PSC67696.1 - 4e-06 26.5 0.0 6.8e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 PSC67696.1 - 0.0018 18.4 0.0 0.0044 17.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein DnaJ_CXXCXGXG PF00684.19 PSC67697.1 - 0.32 11.4 29.8 2.5 8.5 29.8 2.6 1 1 0 1 1 1 0 DnaJ central domain Sulfatase PF00884.23 PSC67698.1 - 9.7e-44 150.0 0.2 1.4e-43 149.5 0.2 1.2 1 0 0 1 1 1 1 Sulfatase Phosphodiest PF01663.22 PSC67698.1 - 0.057 13.0 0.0 0.7 9.4 0.0 2.1 2 0 0 2 2 2 0 Type I phosphodiesterase / nucleotide pyrophosphatase 4HBT PF03061.22 PSC67699.1 - 0.00011 22.5 0.1 0.00025 21.3 0.1 1.6 1 0 0 1 1 1 1 Thioesterase superfamily LPP PF04728.13 PSC67700.1 - 0.0095 16.3 1.0 0.022 15.1 1.0 1.5 1 0 0 1 1 1 1 Lipoprotein leucine-zipper LRR_6 PF13516.6 PSC67700.1 - 0.13 12.4 1.5 5.4 7.3 0.0 2.7 2 0 0 2 2 2 0 Leucine Rich repeat FmdE PF02663.14 PSC67700.1 - 0.18 11.9 0.1 2.8 8.0 0.2 2.1 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon LicD PF04991.13 PSC67704.1 - 6.1e-09 36.3 0.0 1.7e-08 34.9 0.3 1.6 2 0 0 2 2 2 1 LicD family DUF92 PF01940.16 PSC67705.1 - 1.5e-43 149.0 17.4 3.2e-43 147.9 17.4 1.5 1 1 0 1 1 1 1 Integral membrane protein DUF92 CODH_A_N PF18537.1 PSC67705.1 - 0.21 11.6 0.8 0.55 10.3 0.0 2.1 2 0 0 2 2 2 0 Carbon monoxide dehydrogenase subunit alpha N-terminal domain ketoacyl-synt PF00109.26 PSC67706.1 - 1.5e-64 218.0 8.5 2.2e-45 155.2 6.5 2.4 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 PSC67706.1 - 8.3e-26 90.3 0.3 1.5e-25 89.5 0.3 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 PSC67706.1 - 1.6e-13 50.8 0.0 4.4e-07 30.2 0.0 2.8 2 0 0 2 2 2 2 Phosphopantetheine attachment site ketoacyl-synt PF00109.26 PSC67708.1 - 1.6e-46 159.0 0.0 1.6e-46 159.0 0.0 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 PSC67708.1 - 1.1e-33 116.7 7.3 1.6e-33 116.1 7.3 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 PSC67708.1 - 0.06 12.8 2.3 0.092 12.2 2.3 1.2 1 0 0 1 1 1 0 short chain dehydrogenase RVT_2 PF07727.14 PSC67709.1 - 4.7e-74 249.1 0.0 6.1e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) YHYH PF14240.6 PSC67709.1 - 0.02 14.8 0.5 8.9 6.2 0.0 2.7 3 0 0 3 3 3 0 YHYH protein Crr6 PF08847.11 PSC67709.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Chlororespiratory reduction 6 RVT_2 PF07727.14 PSC67710.1 - 8.6e-32 110.7 0.0 1.2e-31 110.2 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Ham1p_like PF01725.16 PSC67711.1 - 3.6e-56 190.1 0.0 4.2e-56 189.8 0.0 1.1 1 0 0 1 1 1 1 Ham1 family IF-2B PF01008.17 PSC67712.1 - 1.6e-35 122.7 0.1 6.5e-35 120.7 0.3 1.7 2 0 0 2 2 2 1 Initiation factor 2 subunit family NUDIX PF00293.28 PSC67712.1 - 3e-10 40.3 0.2 3e-10 40.3 0.2 1.8 2 0 0 2 2 2 1 NUDIX domain Retrotran_gag_2 PF14223.6 PSC67713.1 - 1.6e-25 89.4 0.0 2e-25 89.1 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 PSC67713.1 - 6.2e-06 25.8 0.0 9.8e-06 25.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 PSC67713.1 - 0.016 15.0 0.0 0.036 13.9 0.0 1.5 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type RPN6_N PF18055.1 PSC67714.1 - 3.3e-29 101.6 0.1 1.3e-28 99.7 0.0 2.0 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 PSC67714.1 - 1.3e-19 70.6 0.5 1.1e-18 67.7 0.1 2.5 3 0 0 3 3 3 1 PCI domain RPN6_C_helix PF18503.1 PSC67714.1 - 1.1e-06 28.3 0.0 6.5e-05 22.6 0.0 2.8 3 0 0 3 3 3 1 26S proteasome subunit RPN6 C-terminal helix domain TPR_12 PF13424.6 PSC67714.1 - 1.2e-05 25.4 2.9 0.014 15.6 2.7 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 PSC67714.1 - 0.055 14.1 0.5 0.055 14.1 0.5 3.3 2 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 PSC67714.1 - 0.1 12.8 0.1 3.3 8.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_MalT PF17874.1 PSC67714.1 - 0.11 11.9 13.6 0.019 14.4 6.8 2.2 1 1 1 2 2 2 0 MalT-like TPR region TPR_21 PF09976.9 PSC67714.1 - 0.12 12.0 0.3 0.12 12.0 0.3 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat-like domain Adaptin_N PF01602.20 PSC67715.1 - 3.5e-153 510.9 3.4 4.2e-153 510.7 3.4 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 PSC67715.1 - 1e-65 220.7 0.7 9.2e-63 211.1 0.0 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PSC67715.1 - 8.1e-16 58.2 14.5 1.4e-05 25.4 0.0 6.1 4 2 2 6 6 6 4 HEAT repeats HEAT PF02985.22 PSC67715.1 - 1.1e-08 34.6 5.8 0.053 13.8 0.0 5.3 5 0 0 5 5 4 3 HEAT repeat Cnd3 PF12719.7 PSC67715.1 - 1.4e-08 34.3 0.2 4.8e-07 29.2 0.0 2.5 2 1 1 3 3 3 1 Nuclear condensing complex subunits, C-term domain RTP1_C1 PF10363.9 PSC67715.1 - 0.00022 21.4 1.8 0.91 9.7 0.0 4.7 2 2 1 3 3 3 1 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 PSC67715.1 - 0.001 19.0 4.8 0.95 9.6 0.0 5.5 6 1 0 6 6 6 1 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 PSC67715.1 - 0.0042 16.7 0.3 6.1 6.3 0.0 3.1 2 1 1 3 3 3 2 CLASP N terminal UNC45-central PF11701.8 PSC67715.1 - 0.021 14.8 0.3 1 9.3 0.0 3.3 4 0 0 4 4 4 0 Myosin-binding striated muscle assembly central Arm_2 PF04826.13 PSC67715.1 - 0.051 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 Armadillo-like DUF5578 PF17741.1 PSC67715.1 - 0.14 11.5 0.3 24 4.2 0.0 3.1 3 0 0 3 3 3 0 Family of unknown function (DUF5578) Aminotran_3 PF00202.21 PSC67716.1 - 9.7e-69 232.0 0.1 1.3e-68 231.6 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III NAD_binding_10 PF13460.6 PSC67716.1 - 1.8e-24 86.6 1.9 4.4e-12 46.3 0.0 3.5 2 1 0 2 2 2 2 NAD(P)H-binding NmrA PF05368.13 PSC67716.1 - 3.3e-11 43.2 0.2 1.7e-10 40.9 0.4 2.0 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 PSC67716.1 - 2.7e-08 33.6 0.1 2e-07 30.7 0.1 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family CIA30 PF08547.12 PSC67716.1 - 1.8e-06 28.1 0.0 3.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) NAD_binding_4 PF07993.12 PSC67716.1 - 0.00025 20.3 0.0 0.0005 19.3 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 PSC67716.1 - 0.0018 17.3 0.1 0.0027 16.8 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 PSC67716.1 - 0.0018 17.7 0.0 0.003 17.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 PSC67716.1 - 0.024 13.7 0.4 0.26 10.3 0.1 2.7 3 0 0 3 3 3 0 RmlD substrate binding domain KR PF08659.10 PSC67716.1 - 0.069 13.1 0.4 0.17 11.8 0.4 1.7 1 0 0 1 1 1 0 KR domain adh_short PF00106.25 PSC67716.1 - 0.087 12.3 0.8 0.34 10.3 0.8 2.0 1 1 0 1 1 1 0 short chain dehydrogenase GAS PF13851.6 PSC67717.1 - 0.00053 19.4 18.5 0.00079 18.8 18.5 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Ax_dynein_light PF10211.9 PSC67717.1 - 0.0032 17.4 17.3 0.0049 16.8 4.4 2.1 1 1 1 2 2 2 1 Axonemal dynein light chain APG6_N PF17675.1 PSC67717.1 - 0.0085 16.6 20.7 0.0085 16.6 20.7 2.0 1 1 1 2 2 2 2 Apg6 coiled-coil region Atg14 PF10186.9 PSC67717.1 - 0.027 13.5 16.9 0.036 13.1 16.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lipoprotein_20 PF13942.6 PSC67717.1 - 0.089 12.7 14.1 0.17 11.8 6.7 2.1 1 1 1 2 2 2 0 YfhG lipoprotein GalP_UDP_transf PF01087.22 PSC67717.1 - 0.13 12.7 2.4 0.18 12.2 2.4 1.2 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain TMF_DNA_bd PF12329.8 PSC67717.1 - 0.17 11.9 13.9 0.21 11.6 0.6 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding AIP3 PF03915.13 PSC67717.1 - 0.2 10.7 11.8 0.25 10.4 11.8 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 FapA PF03961.13 PSC67717.1 - 0.23 10.0 6.3 0.35 9.4 6.3 1.3 1 1 0 1 1 1 0 Flagellar Assembly Protein A CorA PF01544.18 PSC67717.1 - 0.23 10.7 10.3 0.29 10.4 9.8 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein Jnk-SapK_ap_N PF09744.9 PSC67717.1 - 0.46 10.7 17.8 0.71 10.1 17.7 1.4 1 1 0 1 1 1 0 JNK_SAPK-associated protein-1 Spc24 PF08286.11 PSC67717.1 - 0.5 10.6 14.9 1.5 9.1 3.7 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Leu_zip PF15294.6 PSC67717.1 - 0.52 9.8 13.3 0.61 9.5 13.3 1.0 1 0 0 1 1 1 0 Leucine zipper Spc7 PF08317.11 PSC67717.1 - 0.53 9.1 21.0 2.7 6.8 21.0 1.8 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF1664 PF07889.12 PSC67717.1 - 0.56 10.3 9.8 1 9.4 5.6 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) FAM76 PF16046.5 PSC67717.1 - 0.56 9.5 11.9 0.88 8.9 11.9 1.3 1 0 0 1 1 1 0 FAM76 protein V_ATPase_I PF01496.19 PSC67717.1 - 0.6 7.9 9.2 0.69 7.8 9.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 PSC67717.1 - 0.61 10.7 12.8 0.57 10.9 3.9 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Taxilin PF09728.9 PSC67717.1 - 0.62 9.2 17.8 1.1 8.3 17.7 1.4 1 1 0 1 1 1 0 Myosin-like coiled-coil protein CENP-F_leu_zip PF10473.9 PSC67717.1 - 0.63 10.1 14.7 3.3 7.8 6.1 2.5 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.21 PSC67717.1 - 0.65 9.5 21.9 0.57 9.7 13.4 2.0 1 1 1 2 2 2 0 Intermediate filament protein FmiP_Thoc5 PF09766.9 PSC67717.1 - 0.75 9.0 12.4 1.3 8.3 12.4 1.4 1 1 0 1 1 1 0 Fms-interacting protein/Thoc5 Tektin PF03148.14 PSC67717.1 - 0.99 8.1 19.5 1.1 8.0 17.6 1.7 1 1 1 2 2 2 0 Tektin family DUF3450 PF11932.8 PSC67717.1 - 1.2 8.4 31.0 7.7 5.7 10.3 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Prefoldin_2 PF01920.20 PSC67717.1 - 1.3 9.0 15.4 0.11 12.5 1.0 3.1 1 1 1 3 3 3 0 Prefoldin subunit PepSY_TM PF03929.16 PSC67717.1 - 1.4 8.5 7.8 1.5 8.4 7.8 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Seryl_tRNA_N PF02403.22 PSC67717.1 - 1.5 9.1 13.7 0.57 10.4 4.9 2.1 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMF_TATA_bd PF12325.8 PSC67717.1 - 1.8 8.8 15.8 0.89 9.8 3.5 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding Bap31_Bap29_C PF18035.1 PSC67717.1 - 1.9 8.6 10.4 1.7 8.7 2.5 2.9 2 2 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain DUF4407 PF14362.6 PSC67717.1 - 2.3 7.5 30.4 2.7 7.3 30.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BLOC1_2 PF10046.9 PSC67717.1 - 2.3 8.6 9.9 4.7 7.6 0.2 2.8 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AATF-Che1 PF13339.6 PSC67717.1 - 2.4 8.8 13.2 2.9 8.6 7.4 2.1 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor DUF3037 PF11236.8 PSC67717.1 - 3.7 8.0 11.1 1.2 9.6 4.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3037) CCDC92 PF14916.6 PSC67717.1 - 3.7 7.4 19.4 4.8 7.0 7.6 4.2 3 2 0 3 3 3 0 Coiled-coil domain of unknown function DUF948 PF06103.11 PSC67717.1 - 4 7.8 11.7 2 8.7 2.7 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.6 PSC67717.1 - 4.5 5.8 11.7 6.9 5.2 11.7 1.3 1 0 0 1 1 1 0 AAA domain CENP-H PF05837.12 PSC67717.1 - 7.3 7.1 24.7 1.5 9.2 7.8 2.2 1 1 1 2 2 2 0 Centromere protein H (CENP-H) DUF4763 PF15960.5 PSC67717.1 - 7.9 5.7 23.7 2.6 7.3 7.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) GCP_N_terminal PF17681.1 PSC67717.1 - 9.7 5.7 10.1 20 4.7 10.1 1.5 1 1 0 1 1 1 0 Gamma tubulin complex component N-terminal GAS PF13851.6 PSC67718.1 - 0.00047 19.6 17.0 0.00055 19.3 17.0 1.0 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding FapA PF03961.13 PSC67718.1 - 0.067 11.8 4.1 0.081 11.5 4.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Atg14 PF10186.9 PSC67718.1 - 0.071 12.2 16.3 0.089 11.9 16.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Prefoldin_2 PF01920.20 PSC67718.1 - 0.09 12.7 0.9 0.09 12.7 0.9 3.0 1 1 1 3 3 3 0 Prefoldin subunit Ax_dynein_light PF10211.9 PSC67718.1 - 0.12 12.4 15.1 2.8 7.8 8.1 2.1 1 1 1 2 2 2 0 Axonemal dynein light chain AIP3 PF03915.13 PSC67718.1 - 0.2 10.7 10.4 0.24 10.5 10.4 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 SICA_beta PF12878.7 PSC67718.1 - 0.32 11.2 3.6 0.38 10.9 3.6 1.1 1 0 0 1 1 1 0 SICA extracellular beta domain TMF_DNA_bd PF12329.8 PSC67718.1 - 0.41 10.7 10.4 0.2 11.7 0.7 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding CALCOCO1 PF07888.11 PSC67718.1 - 0.45 9.3 22.9 0.51 9.1 22.9 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF1664 PF07889.12 PSC67718.1 - 0.58 10.2 8.1 0.96 9.5 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CorA PF01544.18 PSC67718.1 - 0.62 9.3 8.9 0.68 9.2 8.1 1.4 1 1 0 1 1 1 0 CorA-like Mg2+ transporter protein ATG16 PF08614.11 PSC67718.1 - 0.74 10.0 28.2 2.9 8.1 17.9 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) PepSY_TM PF03929.16 PSC67718.1 - 0.9 9.1 7.6 0.95 9.1 7.6 1.1 1 0 0 1 1 1 0 PepSY-associated TM region YabA PF06156.13 PSC67718.1 - 1.1 10.0 10.2 0.39 11.4 3.6 2.2 1 1 1 2 2 2 0 Initiation control protein YabA Spc7 PF08317.11 PSC67718.1 - 1.1 8.1 18.6 3 6.6 18.6 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 PSC67718.1 - 1.3 9.5 24.6 1.4 9.4 18.1 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region DUF4407 PF14362.6 PSC67718.1 - 1.4 8.2 27.1 1.7 7.9 27.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc24 PF08286.11 PSC67718.1 - 3 8.1 12.5 1.8 8.9 4.0 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 GCP_N_terminal PF17681.1 PSC67718.1 - 4.2 6.9 8.0 6.3 6.3 8.0 1.3 1 1 0 1 1 1 0 Gamma tubulin complex component N-terminal THOC7 PF05615.13 PSC67718.1 - 6.8 7.0 20.0 0.32 11.3 4.7 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 V_ATPase_I PF01496.19 PSC67718.1 - 6.9 4.5 8.3 8.5 4.2 8.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PRKG1_interact PF15898.5 PSC67718.1 - 8.3 7.4 14.6 21 6.1 1.9 2.6 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain TetR_C_30 PF17939.1 PSC67719.1 - 0.003 17.8 0.8 0.16 12.2 0.1 3.3 3 0 0 3 3 3 1 Tetracyclin repressor-like, C-terminal domain PP2C PF00481.21 PSC67720.1 - 1.7e-67 227.8 0.1 2.9e-54 184.4 0.1 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 PSC67720.1 - 0.00024 20.8 1.7 0.00024 20.8 1.7 2.9 2 1 1 3 3 3 2 Protein phosphatase 2C Glyco_hydro_88 PF07470.13 PSC67721.1 - 3.7e-09 36.1 2.2 9.2e-09 34.8 2.2 1.9 1 1 0 1 1 1 1 Glycosyl Hydrolase Family 88 DUF740 PF05340.12 PSC67721.1 - 0.14 10.9 0.1 0.19 10.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF740) Gal_Lectin PF02140.18 PSC67722.1 - 4.4e-20 71.9 7.5 7.4e-11 42.3 1.5 3.0 2 1 0 2 2 2 2 Galactose binding lectin domain Pectate_lyase_3 PF12708.7 PSC67722.1 - 1e-14 54.9 0.3 1.5e-13 51.1 0.0 2.2 2 0 0 2 2 2 1 Pectate lyase superfamily protein Chitin_bind_1 PF00187.19 PSC67722.1 - 3.8e-05 24.1 15.2 0.00013 22.3 15.2 2.0 1 0 0 1 1 1 1 Chitin recognition protein Beta_helix PF13229.6 PSC67722.1 - 0.00055 19.8 2.4 0.00086 19.2 2.4 1.3 1 0 0 1 1 1 1 Right handed beta helix region Trypan_PARP PF05887.11 PSC67722.1 - 0.033 14.2 17.7 0.91 9.5 7.8 2.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) End_N_terminal PF12218.8 PSC67722.1 - 0.078 12.7 0.2 0.2 11.4 0.2 1.7 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase TonB_N PF16031.5 PSC67722.1 - 0.21 12.1 45.9 0.35 11.4 8.2 2.9 2 0 0 2 2 2 0 TonB polyproline region tRNA_m1G_MT PF01746.21 PSC67723.1 - 2.6e-12 46.9 0.0 3.5e-11 43.2 0.0 2.0 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase NAS PF03059.16 PSC67723.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Nicotianamine synthase protein CPSase_L_D2 PF02786.17 PSC67724.1 - 1.1e-103 345.3 0.3 8.5e-66 221.5 0.2 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_D3 PF02787.19 PSC67724.1 - 5.4e-39 133.3 0.0 1.3e-38 132.1 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain MGS PF02142.22 PSC67724.1 - 9.2e-22 77.0 0.2 3.6e-21 75.1 0.3 2.1 2 0 0 2 2 1 1 MGS-like domain ATP-grasp PF02222.22 PSC67724.1 - 6.4e-14 51.9 0.0 5.4e-10 39.1 0.0 2.3 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.13 PSC67724.1 - 6.8e-11 42.1 0.1 1.7e-07 31.0 0.0 2.4 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 PSC67724.1 - 5.4e-10 39.1 0.1 0.00014 21.6 0.0 3.1 2 1 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.6 PSC67724.1 - 4.7e-09 36.1 0.0 1.5e-05 24.7 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_3 PF02655.14 PSC67724.1 - 1.6e-06 28.3 0.1 0.003 17.6 0.0 2.7 2 0 0 2 2 2 2 ATP-grasp domain ATP-grasp_2 PF08442.10 PSC67724.1 - 0.0045 16.6 0.0 0.45 10.0 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain DUF4176 PF13780.6 PSC67724.1 - 0.0074 16.3 0.0 4.9 7.3 0.0 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4176) ATP-grasp_5 PF13549.6 PSC67724.1 - 0.0075 15.7 0.0 1.2 8.6 0.0 2.6 2 0 0 2 2 2 1 ATP-grasp domain ADH_zinc_N PF00107.26 PSC67724.1 - 0.026 14.5 0.0 1.2 9.1 0.0 3.1 2 0 0 2 2 2 0 Zinc-binding dehydrogenase RVT_2 PF07727.14 PSC67725.1 - 2.2e-52 178.1 0.0 3.2e-52 177.6 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 PSC67725.1 - 1.9e-24 85.9 0.0 3.4e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 PSC67725.1 - 3.6e-24 85.2 0.0 8.3e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 PSC67725.1 - 2.2e-09 37.1 0.0 4.3e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4219 PF13961.6 PSC67725.1 - 3.3e-05 23.4 0.0 7e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) rve_3 PF13683.6 PSC67725.1 - 6.9e-05 22.5 0.0 0.00029 20.5 0.0 2.1 3 0 0 3 3 3 1 Integrase core domain Asp_protease_2 PF13650.6 PSC67725.1 - 0.07 13.8 0.1 0.65 10.7 0.0 2.3 2 0 0 2 2 2 0 Aspartyl protease Retrotran_gag_3 PF14244.6 PSC67725.1 - 0.089 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 PSC67725.1 - 0.12 12.2 2.0 0.23 11.2 2.0 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_3 PF13917.6 PSC67725.1 - 0.12 12.4 0.3 0.31 11.0 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle Crr6 PF08847.11 PSC67725.1 - 0.17 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 Chlororespiratory reduction 6 zf-HC5HC2H PF13771.6 PSC67726.1 - 0.0014 18.8 3.9 0.0014 18.8 3.9 1.9 2 0 0 2 2 2 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 PSC67726.1 - 0.011 15.8 3.4 0.011 15.8 3.4 2.2 2 0 0 2 2 2 0 PHD-zinc-finger like domain SET PF00856.28 PSC67726.1 - 0.075 13.4 4.0 0.1 13.0 0.0 3.0 4 0 0 4 4 4 0 SET domain Zn_ribbon_17 PF17120.5 PSC67726.1 - 3.5 7.3 7.3 10 5.8 7.3 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type rve PF00665.26 PSC67727.1 - 1.3e-18 67.3 0.0 2.8e-18 66.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC67727.1 - 0.0089 15.8 0.0 0.027 14.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain HATPase_c_3 PF13589.6 PSC67728.1 - 1.9e-08 34.2 0.0 1.9e-08 34.2 0.0 2.3 2 0 0 2 2 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Exonuc_VII_L PF02601.15 PSC67728.1 - 1.3e-05 24.9 14.4 2.2e-05 24.2 14.4 1.4 1 0 0 1 1 1 1 Exonuclease VII, large subunit Sin_N PF04801.13 PSC67728.1 - 0.00028 20.3 33.8 0.00037 19.8 33.8 1.1 1 0 0 1 1 1 1 Sin-like protein conserved region Tim54 PF11711.8 PSC67728.1 - 0.00036 19.4 14.0 0.00064 18.6 14.0 1.4 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 PSC67728.1 - 0.00085 18.2 33.5 0.0013 17.6 33.5 1.1 1 0 0 1 1 1 1 Presenilin MMR1 PF08505.10 PSC67728.1 - 0.0018 18.6 26.0 0.003 17.9 26.0 1.3 1 0 0 1 1 1 1 Mitochondrial Myo2 receptor-related protein BAF1_ABF1 PF04684.13 PSC67728.1 - 0.0019 17.3 17.4 0.0026 16.9 17.4 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor PAT1 PF09770.9 PSC67728.1 - 0.0022 16.3 48.3 0.0032 15.8 48.3 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 HATPase_c PF02518.26 PSC67728.1 - 0.0045 17.5 0.0 0.012 16.1 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SAPS PF04499.15 PSC67728.1 - 0.0062 15.4 14.5 0.0085 14.9 14.5 1.1 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein DUF1382 PF07131.11 PSC67728.1 - 0.018 15.0 0.1 0.047 13.7 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1382) DUF4045 PF13254.6 PSC67728.1 - 0.029 14.0 23.9 0.042 13.5 23.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) DUF5427 PF10310.9 PSC67728.1 - 0.034 13.1 31.6 0.052 12.5 31.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) HATPase_c_2 PF13581.6 PSC67728.1 - 0.04 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain Dapper PF15268.6 PSC67728.1 - 0.048 12.5 29.1 0.069 12.0 29.1 1.1 1 0 0 1 1 1 0 Dapper Lin-8 PF03353.15 PSC67728.1 - 0.056 13.0 34.2 0.082 12.5 34.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF3295 PF11702.8 PSC67728.1 - 0.1 12.0 24.9 0.15 11.4 24.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Otopetrin PF03189.13 PSC67728.1 - 0.11 11.3 10.0 0.16 10.7 10.0 1.2 1 0 0 1 1 1 0 Otopetrin Hid1 PF12722.7 PSC67728.1 - 0.12 10.4 25.8 0.17 10.0 25.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Apt1 PF10351.9 PSC67728.1 - 0.12 11.2 16.9 0.17 10.7 16.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain GREB1 PF15782.5 PSC67728.1 - 0.13 9.4 27.0 0.17 9.0 27.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer WTX PF09422.10 PSC67728.1 - 0.14 11.2 16.3 0.23 10.5 16.3 1.3 1 0 0 1 1 1 0 WTX protein Pkinase_fungal PF17667.1 PSC67728.1 - 0.15 10.8 9.7 0.21 10.3 9.7 1.2 1 0 0 1 1 1 0 Fungal protein kinase Smg8_Smg9 PF10220.9 PSC67728.1 - 0.15 10.4 24.1 0.2 9.9 24.1 1.1 1 0 0 1 1 1 0 Smg8_Smg9 SAGA-Tad1 PF12767.7 PSC67728.1 - 0.17 11.6 22.7 0.29 10.8 22.7 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF572 PF04502.13 PSC67728.1 - 0.22 11.1 23.8 0.35 10.5 23.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Senescence_reg PF04520.13 PSC67728.1 - 0.67 10.8 19.4 1.6 9.5 19.4 1.7 1 0 0 1 1 1 0 Senescence regulator Ndc1_Nup PF09531.10 PSC67728.1 - 0.76 8.4 27.4 1 8.0 27.4 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SID-1_RNA_chan PF13965.6 PSC67728.1 - 0.84 8.0 12.0 1.2 7.5 12.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Velvet PF11754.8 PSC67728.1 - 1.1 9.1 27.7 2.2 8.1 27.7 1.5 1 0 0 1 1 1 0 Velvet factor VIT1 PF01988.19 PSC67728.1 - 1.2 9.0 11.4 2.6 7.8 11.4 1.5 1 0 0 1 1 1 0 VIT family DUF913 PF06025.12 PSC67728.1 - 1.6 7.6 16.9 3.4 6.6 16.9 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) AF-4 PF05110.13 PSC67728.1 - 2.3 6.2 33.8 3 5.8 33.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Endostatin PF06482.11 PSC67728.1 - 2.3 7.6 29.1 3.8 6.9 29.1 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin CCSAP PF15748.5 PSC67728.1 - 2.4 8.3 38.5 4.2 7.5 38.5 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated TCP PF03634.13 PSC67728.1 - 4.1 8.0 30.8 7.9 7.0 30.8 1.4 1 0 0 1 1 1 0 TCP family transcription factor BORG_CEP PF14957.6 PSC67728.1 - 4.6 8.4 21.3 10 7.3 21.3 1.5 1 0 0 1 1 1 0 Cdc42 effector Paramyxo_ncap PF00973.19 PSC67728.1 - 5.5 5.8 23.5 8 5.3 23.5 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein RR_TM4-6 PF06459.12 PSC67728.1 - 6 6.6 38.0 9.1 6.0 38.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hydin_ADK PF17213.3 PSC67728.1 - 8.7 6.6 25.8 18 5.5 25.8 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain cobW PF02492.19 PSC67729.1 - 2.5e-51 173.8 0.4 3.8e-51 173.2 0.4 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 PSC67729.1 - 3.7e-23 81.3 0.1 2e-17 62.9 0.0 3.1 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain Thioredoxin PF00085.20 PSC67729.1 - 0.00042 20.3 0.0 0.89 9.6 0.0 2.5 2 0 0 2 2 2 2 Thioredoxin TsaE PF02367.17 PSC67729.1 - 0.14 12.1 0.0 0.34 10.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 PSC67729.1 - 0.18 12.2 0.0 0.18 12.2 0.0 3.9 4 0 0 4 4 4 0 AAA ATPase domain Pkinase PF00069.25 PSC67730.1 - 4.2e-67 226.3 0.0 5.3e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC67730.1 - 5.2e-48 163.6 0.0 7.5e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PSC67730.1 - 1e-05 24.5 0.0 1.5e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase ABC1 PF03109.16 PSC67730.1 - 0.012 15.7 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Kinase-like PF14531.6 PSC67730.1 - 0.022 14.1 0.0 0.061 12.6 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 PSC67730.1 - 0.21 10.5 0.0 1.7 7.5 0.0 1.9 2 0 0 2 2 2 0 Haspin like kinase domain CcmD PF04995.14 PSC67730.1 - 3.5 7.8 5.1 0.69 10.0 0.6 2.2 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Herpes_capsid PF06112.11 PSC67731.1 - 1.2 9.2 7.6 1.4 9.0 7.6 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein APH PF01636.23 PSC67732.1 - 3.8e-17 63.0 14.0 5.1e-13 49.5 6.3 2.7 2 2 0 2 2 2 2 Phosphotransferase enzyme family APH PF01636.23 PSC67733.1 - 1.6e-16 61.0 14.0 2.2e-12 47.4 6.4 2.7 2 2 0 2 2 2 2 Phosphotransferase enzyme family CTP_synth_N PF06418.14 PSC67734.1 - 2.8e-126 420.2 0.0 3.8e-126 419.8 0.0 1.2 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 PSC67734.1 - 6.9e-59 198.8 0.0 1e-58 198.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 PSC67734.1 - 3.1e-05 23.8 0.0 0.00012 21.9 0.0 2.1 1 1 0 1 1 1 1 Peptidase C26 CbiA PF01656.23 PSC67734.1 - 0.0085 16.2 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 PSC67734.1 - 0.11 11.4 1.7 0.22 10.5 1.7 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF2064 PF09837.9 PSC67736.1 - 1.6e-21 76.4 0.8 2.6e-20 72.5 0.1 2.1 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2064) CofC PF01983.16 PSC67736.1 - 2.5e-05 23.6 0.0 3e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Guanylyl transferase CofC like NTP_transf_3 PF12804.7 PSC67736.1 - 0.13 12.6 4.2 0.35 11.2 4.2 1.7 1 1 0 1 1 1 0 MobA-like NTP transferase domain SNF5 PF04855.12 PSC67737.1 - 2.9e-06 27.3 0.0 0.072 12.9 0.0 2.2 1 1 1 2 2 2 2 SNF5 / SMARCB1 / INI1 Pkinase PF00069.25 PSC67738.1 - 1.7e-36 125.9 0.0 3.1e-36 125.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC67738.1 - 2.3e-17 63.2 0.0 3.3e-17 62.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC67738.1 - 0.00013 21.4 0.0 0.019 14.3 0.0 2.6 2 0 0 2 2 2 1 Kinase-like Spc29 PF17082.5 PSC67738.1 - 0.03 14.2 1.3 0.094 12.6 0.0 2.0 2 0 0 2 2 2 0 Spindle Pole Component 29 DUF641 PF04859.12 PSC67738.1 - 0.04 14.3 0.6 0.04 14.3 0.6 1.9 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) PRKG1_interact PF15898.5 PSC67738.1 - 0.1 13.5 0.2 0.1 13.5 0.2 2.4 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain CCDC106 PF15794.5 PSC67738.1 - 0.15 11.7 1.7 4.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 PKcGMP_CC PF16808.5 PSC67738.1 - 3.2 7.7 8.5 0.52 10.2 4.2 1.9 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Peptidase_M20 PF01546.28 PSC67739.1 - 5.2e-33 114.5 0.8 8.1e-33 113.9 0.8 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PSC67739.1 - 8.5e-12 45.0 0.2 2e-11 43.8 0.2 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain OTU PF02338.19 PSC67740.1 - 0.0005 20.6 0.0 0.0011 19.4 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease VIR_N PF15912.5 PSC67741.1 - 1.6 8.3 0.0 1.6 8.3 0.0 5.6 5 1 1 6 6 6 0 Virilizer, N-terminal TFIIA PF03153.13 PSC67742.1 - 4.3 7.2 31.8 0.66 9.9 26.6 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ZapB PF06005.12 PSC67742.1 - 5.4 7.5 20.2 0.16 12.4 6.5 3.1 3 0 0 3 3 3 0 Cell division protein ZapB Peptidase_C1 PF00112.23 PSC67743.1 - 7.5e-69 232.1 0.2 1.2e-68 231.5 0.2 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PSC67743.1 - 1.2e-12 48.0 0.1 2.8e-12 46.9 0.0 1.6 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PSC67743.1 - 0.001 17.9 0.5 0.51 9.1 0.1 2.2 2 0 0 2 2 2 2 Peptidase C1-like family RVT_2 PF07727.14 PSC67744.1 - 2.2e-73 246.9 0.0 3e-73 246.5 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PSC67744.1 - 2.8e-31 108.2 0.0 5.7e-17 62.0 0.0 2.7 2 0 0 2 2 2 2 Integrase core domain Retrotran_gag_2 PF14223.6 PSC67744.1 - 3.8e-24 84.9 0.0 8.3e-24 83.8 0.0 1.6 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 PSC67744.1 - 6.1e-17 61.2 0.0 4.2e-07 29.7 0.0 2.6 2 0 0 2 2 2 2 GAG-pre-integrase domain Asp_protease_2 PF13650.6 PSC67744.1 - 1.1e-06 29.1 0.6 1.1 9.9 0.0 4.2 4 0 0 4 4 4 2 Aspartyl protease zf-CCHC_3 PF13917.6 PSC67744.1 - 7.8e-06 25.8 10.0 0.66 10.0 0.3 3.8 3 0 0 3 3 3 3 Zinc knuckle DUF4219 PF13961.6 PSC67744.1 - 8.1e-05 22.2 0.0 0.00015 21.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) PD40 PF07676.12 PSC67744.1 - 0.00012 21.9 0.2 14 5.8 0.0 3.9 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat zf-C2H2_10 PF16588.5 PSC67744.1 - 0.00039 20.1 20.7 0.47 10.2 2.0 3.4 3 0 0 3 3 3 3 C2H2 zinc-finger gag-asp_proteas PF13975.6 PSC67744.1 - 0.0066 17.0 0.0 38 4.9 0.0 4.0 4 0 0 4 4 4 0 gag-polyprotein putative aspartyl protease zf-CCHC_5 PF14787.6 PSC67744.1 - 0.014 15.1 22.8 1.5 8.6 2.5 3.7 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger Retrotran_gag_3 PF14244.6 PSC67744.1 - 0.18 11.7 0.0 0.43 10.4 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type TruD PF01142.18 PSC67745.1 - 5.3e-68 229.7 0.0 4.6e-62 210.2 0.0 3.1 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) ANAPC_CDC26 PF10471.9 PSC67745.1 - 0.66 10.9 3.6 0.41 11.5 0.1 2.5 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 Glyco_hydro_9 PF00759.19 PSC67746.1 - 2.8e-78 264.2 5.7 1.3e-76 258.7 5.7 2.2 1 1 0 1 1 1 1 Glycosyl hydrolase family 9 HECT PF00632.25 PSC67747.1 - 8.9e-90 301.3 0.0 1.1e-89 300.9 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) IQ PF00612.27 PSC67747.1 - 0.0061 16.2 2.9 0.022 14.5 2.9 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif Atx10homo_assoc PF09759.9 PSC67748.1 - 3.2e-26 91.2 0.0 6.5e-26 90.2 0.0 1.5 1 0 0 1 1 1 1 Spinocerebellar ataxia type 10 protein domain Synaptobrevin PF00957.21 PSC67750.1 - 5.4e-14 51.7 0.1 8.8e-14 51.1 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 PSC67750.1 - 1.4e-07 31.4 0.0 2.2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain MIT PF04212.18 PSC67750.1 - 0.031 14.4 0.2 0.053 13.6 0.2 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain Synaptobrevin PF00957.21 PSC67751.1 - 5.4e-14 51.7 0.1 8.8e-14 51.1 0.1 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 PSC67751.1 - 1.4e-07 31.4 0.0 2.2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain MIT PF04212.18 PSC67751.1 - 0.031 14.4 0.2 0.053 13.6 0.2 1.4 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain SKN1 PF03935.15 PSC67752.1 - 0.0074 14.7 0.0 0.0074 14.7 0.0 1.1 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) fn3 PF00041.21 PSC67753.1 - 0.027 14.8 0.1 9.7 6.6 0.0 3.6 4 0 0 4 4 4 0 Fibronectin type III domain Ribosomal_L23eN PF03939.13 PSC67754.1 - 9.2e-16 57.8 10.9 9.2e-16 57.8 10.9 2.2 2 0 0 2 2 2 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 PSC67754.1 - 8e-13 48.6 1.5 8e-13 48.6 1.5 2.4 2 1 0 2 2 2 1 Ribosomal protein L23 PP-binding PF00550.25 PSC67755.1 - 3.7e-23 81.7 0.2 5.2e-11 42.7 0.1 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site KR PF08659.10 PSC67755.1 - 1.5e-19 70.6 1.3 3.4e-19 69.5 1.3 1.6 1 0 0 1 1 1 1 KR domain Nucleoporin2 PF04096.14 PSC67755.1 - 0.011 15.8 0.0 0.02 15.0 0.0 1.3 1 0 0 1 1 1 0 Nucleoporin autopeptidase CxC4 PF18717.1 PSC67756.1 - 0.00047 20.0 0.5 0.0017 18.2 0.2 2.1 2 0 0 2 2 2 1 CxC4 like cysteine cluster associated with KDZ transposases KDZ PF18758.1 PSC67756.1 - 0.0045 16.6 0.2 0.0067 16.1 0.2 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase TP_methylase PF00590.20 PSC67757.1 - 5.5e-21 75.5 0.2 8.9e-21 74.8 0.2 1.3 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases GST_N_3 PF13417.6 PSC67757.1 - 7.5e-06 26.3 0.0 1.6e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PSC67757.1 - 4.4e-05 23.4 0.1 0.00017 21.5 0.1 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PSC67757.1 - 0.073 13.3 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 PSC67757.1 - 0.076 13.3 0.0 0.18 12.1 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PSC67757.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CAP_N PF01213.19 PSC67758.1 - 1.1 8.6 5.0 0.24 10.8 1.3 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Retrotran_gag_2 PF14223.6 PSC67759.1 - 1.3e-50 170.6 0.0 7e-24 84.1 0.0 2.4 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 PSC67759.1 - 2.9e-17 62.3 0.0 3.6e-07 29.9 0.0 2.5 2 0 0 2 2 2 2 GAG-pre-integrase domain DUF4219 PF13961.6 PSC67759.1 - 4.5e-12 45.3 0.1 0.00013 21.6 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4219) rve PF00665.26 PSC67759.1 - 6.3e-12 45.7 0.0 0.0002 21.5 0.0 2.5 2 0 0 2 2 2 2 Integrase core domain Asp_protease_2 PF13650.6 PSC67759.1 - 1.3e-06 28.9 0.1 0.96 10.1 0.0 3.6 3 0 0 3 3 3 2 Aspartyl protease Retrotran_gag_3 PF14244.6 PSC67759.1 - 3e-05 23.7 0.0 0.37 10.6 0.0 2.5 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 PSC67759.1 - 0.0008 19.1 19.3 0.41 10.4 2.0 3.4 3 0 0 3 3 3 3 C2H2 zinc-finger zf-CCHC_3 PF13917.6 PSC67759.1 - 0.0079 16.1 11.7 0.57 10.2 0.3 3.6 3 0 0 3 3 3 2 Zinc knuckle PD40 PF07676.12 PSC67759.1 - 0.0084 16.0 0.2 12 6.0 0.0 3.4 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat gag-asp_proteas PF13975.6 PSC67759.1 - 0.0097 16.4 0.0 33 5.1 0.0 3.4 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease zf-CCHC_5 PF14787.6 PSC67759.1 - 0.051 13.3 20.0 1.3 8.8 2.5 3.5 3 0 0 3 3 3 0 GAG-polyprotein viral zinc-finger PRY PF13765.6 PSC67759.1 - 0.053 13.2 0.4 1.2e+02 2.5 0.0 5.3 5 0 0 5 5 5 0 SPRY-associated domain Arc_C PF18162.1 PSC67759.1 - 0.064 13.1 1.3 1.1e+02 2.8 0.0 4.4 5 0 0 5 5 5 0 Arc C-lobe GMC_oxred_N PF00732.19 PSC67760.1 - 3e-74 250.1 0.0 4.1e-74 249.6 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PSC67760.1 - 8.2e-34 117.2 0.0 1.7e-33 116.2 0.0 1.6 1 0 0 1 1 1 1 GMC oxidoreductase NAD_binding_8 PF13450.6 PSC67760.1 - 0.017 15.4 0.4 0.073 13.3 0.4 2.2 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 PSC67760.1 - 0.057 12.5 0.2 0.099 11.7 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein MFS_1 PF07690.16 PSC67761.1 - 5.1e-08 32.2 26.5 5.1e-08 32.2 26.5 3.0 2 2 0 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 PSC67761.1 - 0.2 9.9 3.8 0.39 8.9 3.8 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF3302 PF11742.8 PSC67761.1 - 0.2 11.8 0.7 0.44 10.7 0.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3302) Na_K-ATPase PF00287.18 PSC67761.1 - 0.3 10.2 0.1 0.43 9.7 0.1 1.2 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain 5_nucleotid_C PF02872.18 PSC67762.1 - 4.1e-23 82.3 0.0 8e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 PSC67762.1 - 7.7e-12 46.1 0.0 1.1e-11 45.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PGA_cap PF09587.10 PSC67762.1 - 0.0011 18.5 0.4 0.0034 16.9 0.4 1.8 1 1 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Sulfotransfer_2 PF03567.14 PSC67763.1 - 0.013 15.4 0.0 0.047 13.6 0.0 1.9 1 1 0 1 1 1 0 Sulfotransferase family Ufd2P_core PF10408.9 PSC67765.1 - 8.7e-145 483.8 0.0 1e-144 483.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 PSC67765.1 - 2.6e-19 69.1 0.0 1.2e-18 67.0 0.0 2.1 2 0 0 2 2 2 1 U-box domain Pkinase PF00069.25 PSC67765.1 - 2.2e-18 66.6 0.0 1.5e-17 63.8 0.0 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC67765.1 - 1.5e-09 37.5 0.0 3.9e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 PSC67765.1 - 0.00027 20.3 0.0 0.00055 19.4 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PSC67765.1 - 0.00056 19.9 0.0 0.00056 19.9 0.0 4.0 4 1 0 4 4 4 1 Phosphotransferase enzyme family FTA2 PF13095.6 PSC67765.1 - 0.0063 16.2 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 PSC67765.1 - 0.029 13.2 0.4 0.096 11.4 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Kinase-like PF14531.6 PSC67765.1 - 0.051 12.9 0.0 0.088 12.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Haspin_kinase PF12330.8 PSC67765.1 - 0.15 11.0 0.0 0.24 10.3 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain FA_desaturase_2 PF03405.14 PSC67766.1 - 6.3e-149 495.2 0.0 7.3e-149 495.0 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Fasciclin PF02469.22 PSC67768.1 - 0.001 19.3 0.0 0.0013 18.9 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain GHMP_kinases_C PF08544.13 PSC67769.1 - 2.1e-11 44.0 0.2 5.3e-11 42.7 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 PSC67769.1 - 1.4e-09 38.1 4.1 4.2e-09 36.5 4.1 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain DUF5061 PF16587.5 PSC67769.1 - 0.0045 17.0 0.0 0.0045 17.0 0.0 1.7 2 0 0 2 2 2 1 17 kDa common-antigen outer membrane protein Pyridoxal_deC PF00282.19 PSC67770.1 - 9.1e-111 370.2 0.0 1.2e-110 369.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Beta_elim_lyase PF01212.21 PSC67770.1 - 0.049 12.9 0.0 0.065 12.5 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase Pkinase PF00069.25 PSC67771.1 - 9.7e-44 149.7 0.0 2.2e-43 148.5 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC67771.1 - 9.3e-41 139.8 0.0 2.8e-40 138.2 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase VSP PF03302.13 PSC67771.1 - 0.00011 21.2 0.4 0.00026 20.0 0.4 1.6 1 0 0 1 1 1 1 Giardia variant-specific surface protein DAP10 PF07213.11 PSC67771.1 - 0.0096 15.9 0.6 0.035 14.1 0.6 2.0 1 0 0 1 1 1 1 DAP10 membrane protein Pkinase_fungal PF17667.1 PSC67771.1 - 0.014 14.2 0.0 0.019 13.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase PAN_1 PF00024.26 PSC67771.1 - 0.053 13.5 10.5 0.94 9.5 0.5 3.1 3 1 0 3 3 3 0 PAN domain Kinase-like PF14531.6 PSC67771.1 - 0.08 12.2 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Kinase-like PAN_4 PF14295.6 PSC67771.1 - 0.17 11.8 13.7 5.1 7.1 0.9 4.4 4 0 0 4 4 4 0 PAN domain Trypsin PF00089.26 PSC67772.1 - 1.5e-09 38.0 0.2 3.7e-09 36.7 0.2 1.6 1 0 0 1 1 1 1 Trypsin Fasciclin PF02469.22 PSC67773.1 - 0.013 15.7 0.0 0.021 15.1 0.0 1.3 1 0 0 1 1 1 0 Fasciclin domain LCIB_C_CA PF18599.1 PSC67774.1 - 6.4e-75 251.2 0.0 9.5e-75 250.7 0.0 1.3 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Peptidase_S8 PF00082.22 PSC67774.1 - 1.6e-29 103.1 0.5 2.9e-29 102.3 0.5 1.4 1 0 0 1 1 1 1 Subtilase family Glyco_transf_92 PF01697.27 PSC67774.1 - 3.9e-19 69.3 0.0 5.7e-19 68.8 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 CBM_20 PF00686.19 PSC67774.1 - 3.5e-13 49.3 0.0 6.9e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain Glyco_tranf_2_4 PF13704.6 PSC67774.1 - 1.2e-07 32.1 0.0 2.9e-07 30.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 PAN_4 PF14295.6 PSC67774.1 - 0.034 14.1 1.8 0.068 13.1 0.7 2.2 2 0 0 2 2 2 0 PAN domain PAP_assoc PF03828.19 PSC67775.1 - 5.8e-14 52.1 0.1 5.8e-14 52.1 0.1 1.9 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 PSC67775.1 - 9.2e-12 45.1 0.2 2.4e-11 43.8 0.0 1.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain Polbeta PF18765.1 PSC67775.1 - 0.028 14.5 0.0 0.053 13.6 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase SWIRM-assoc_2 PF16496.5 PSC67775.1 - 9.3 5.0 21.6 14 4.4 21.6 1.2 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Fasciclin PF02469.22 PSC67777.1 - 0.00054 20.2 0.0 0.00083 19.6 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain Fasciclin PF02469.22 PSC67778.1 - 0.00016 21.9 0.0 0.00021 21.5 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain DUF2243 PF10002.9 PSC67778.1 - 0.042 14.0 0.0 6.9 6.8 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2243) Fasciclin PF02469.22 PSC67779.1 - 0.00014 22.1 0.0 0.00019 21.7 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain DUF2243 PF10002.9 PSC67779.1 - 0.037 14.1 0.0 6.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2243) DUF3598 PF12204.8 PSC67780.1 - 0.18 11.3 0.0 0.47 9.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3598) RICTOR_phospho PF14665.6 PSC67782.1 - 0.11 12.8 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site DPBB_1 PF03330.18 PSC67783.1 - 2.7e-07 30.8 0.0 5.8e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase KR PF08659.10 PSC67784.1 - 4.1e-29 101.8 2.0 8.8e-29 100.7 2.0 1.5 1 0 0 1 1 1 1 KR domain PP-binding PF00550.25 PSC67784.1 - 1.6e-20 73.2 0.1 2.9e-09 37.1 0.0 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site adh_short_C2 PF13561.6 PSC67784.1 - 8.7e-07 28.7 1.4 1.8e-06 27.7 1.4 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Nucleoporin2 PF04096.14 PSC67784.1 - 1.6e-05 25.0 0.0 2.8e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase adh_short PF00106.25 PSC67784.1 - 0.002 17.6 1.1 0.0047 16.4 1.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase zf-Tim10_DDP PF02953.15 PSC67785.1 - 1.4e-16 59.9 0.4 1.6e-16 59.7 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 PSC67785.1 - 0.057 13.1 0.5 0.37 10.5 0.6 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) zf-Tim10_DDP PF02953.15 PSC67786.1 - 1.4e-16 59.9 0.4 1.6e-16 59.7 0.4 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 PSC67786.1 - 0.057 13.1 0.5 0.37 10.5 0.6 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) OTCace_N PF02729.21 PSC67787.1 - 5.4e-46 156.3 0.3 2.6e-45 154.0 0.1 2.0 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain OTCace PF00185.24 PSC67787.1 - 3.2e-32 111.8 0.0 5.9e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain PsbQ PF05757.11 PSC67788.1 - 0.0023 17.7 3.9 0.0027 17.5 3.9 1.2 1 0 0 1 1 1 1 Oxygen evolving enhancer protein 3 (PsbQ) RmlD_sub_bind PF04321.17 PSC67789.1 - 4.3e-35 121.2 0.0 2.9e-27 95.5 0.0 2.2 2 0 0 2 2 2 2 RmlD substrate binding domain Epimerase PF01370.21 PSC67789.1 - 1.2e-11 44.6 0.0 8.2e-05 22.2 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PSC67789.1 - 6e-05 22.6 0.0 0.016 14.6 0.0 2.6 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase DUF2722 PF10846.8 PSC67789.1 - 0.00021 20.4 5.5 0.00025 20.1 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 PSC67789.1 - 0.0021 18.1 14.2 0.0028 17.7 14.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit adh_short PF00106.25 PSC67789.1 - 0.012 15.0 1.9 0.014 14.8 0.0 2.0 2 0 0 2 2 2 0 short chain dehydrogenase Med15 PF09606.10 PSC67789.1 - 0.035 12.8 20.7 0.054 12.2 20.7 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal NAD_binding_4 PF07993.12 PSC67789.1 - 0.14 11.3 0.8 0.35 10.0 0.0 2.0 3 0 0 3 3 3 0 Male sterility protein Presenilin PF01080.17 PSC67789.1 - 0.23 10.2 3.6 0.32 9.7 3.6 1.1 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 PSC67789.1 - 0.33 10.9 7.4 0.47 10.4 7.4 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.13 PSC67789.1 - 0.37 11.4 8.7 0.66 10.6 8.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Plasmodium_Vir PF05795.11 PSC67789.1 - 0.6 9.5 1.6 0.81 9.0 1.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Band_3_cyto PF07565.13 PSC67789.1 - 0.73 9.6 3.4 1.1 9.0 3.4 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Roughex PF06020.11 PSC67789.1 - 0.97 8.5 3.6 1.4 8.0 3.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein EIIBC-GUT_N PF03612.14 PSC67789.1 - 1.1 9.0 8.7 0.69 9.6 6.9 1.6 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus Neur_chan_memb PF02932.16 PSC67789.1 - 1.8 8.6 3.0 2.5 8.1 3.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Tmemb_14 PF03647.13 PSC67790.1 - 1.7e-21 76.8 5.3 2.1e-21 76.5 5.3 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Tmemb_14 PF03647.13 PSC67791.1 - 1.7e-21 76.8 5.3 2.1e-21 76.5 5.3 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C Isochorismatase PF00857.20 PSC67792.1 - 4.3e-38 131.2 0.0 5.6e-38 130.9 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Peripla_BP_4 PF13407.6 PSC67792.1 - 0.071 12.7 0.0 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Periplasmic binding protein domain PhdYeFM_antitox PF02604.19 PSC67792.1 - 0.18 11.6 0.0 0.36 10.7 0.0 1.4 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system rve PF00665.26 PSC67793.1 - 8.4e-19 67.9 0.0 1.8e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC67793.1 - 0.0067 16.2 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Thymidylat_synt PF00303.19 PSC67794.1 - 1.9e-109 364.9 0.0 2.6e-109 364.5 0.0 1.2 1 0 0 1 1 1 1 Thymidylate synthase fn3 PF00041.21 PSC67794.1 - 1.3e-33 115.1 0.0 4.4e-05 23.7 0.0 7.5 7 0 0 7 7 7 7 Fibronectin type III domain DHFR_1 PF00186.19 PSC67794.1 - 1.6e-23 83.1 0.0 4.1e-23 81.8 0.0 1.7 1 1 0 1 1 1 1 Dihydrofolate reductase Pur_ac_phosph_N PF16656.5 PSC67794.1 - 7.4e-07 29.7 6.2 12 6.5 0.1 7.0 5 2 2 7 7 7 1 Purple acid Phosphatase, N-terminal domain Glyco_hydro_36C PF16874.5 PSC67794.1 - 0.00041 20.8 0.0 8.1 7.0 0.0 5.5 7 0 0 7 7 7 1 Glycosyl hydrolase family 36 C-terminal domain DUF2369 PF10179.9 PSC67794.1 - 0.18 12.2 0.0 86 3.6 0.0 3.7 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2369) SufE PF02657.15 PSC67797.1 - 2.5e-40 137.1 0.0 3.6e-40 136.6 0.0 1.2 1 0 0 1 1 1 1 Fe-S metabolism associated domain BolA PF01722.18 PSC67797.1 - 3.6e-28 97.7 0.0 5.6e-28 97.0 0.0 1.3 1 0 0 1 1 1 1 BolA-like protein DPBB_1 PF03330.18 PSC67798.1 - 1.4e-07 31.6 0.0 3.1e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Lytic transglycolase Pantoate_transf PF02548.15 PSC67800.1 - 7.6e-110 366.4 3.9 9.9e-110 366.0 3.9 1.1 1 0 0 1 1 1 1 Ketopantoate hydroxymethyltransferase PEP_mutase PF13714.6 PSC67800.1 - 0.0017 17.9 0.7 0.0017 17.9 0.7 2.5 2 1 0 2 2 2 1 Phosphoenolpyruvate phosphomutase Asp_Glu_race PF01177.22 PSC67800.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.5 1 0 0 1 1 1 0 Asp/Glu/Hydantoin racemase RICTOR_phospho PF14665.6 PSC67801.1 - 0.11 12.8 0.0 0.13 12.6 0.0 1.2 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, phosphorylation-site dsrm PF00035.26 PSC67802.1 - 0.053 14.2 0.0 0.053 14.2 0.0 2.0 2 0 0 2 2 2 0 Double-stranded RNA binding motif Prenyltrans PF00432.21 PSC67803.1 - 9.2e-40 134.1 15.8 2.8e-11 42.9 0.0 5.7 5 0 0 5 5 5 5 Prenyltransferase and squalene oxidase repeat FA_desaturase PF00487.24 PSC67804.1 - 3.3e-23 82.8 19.5 4.3e-23 82.5 17.8 1.9 1 1 1 2 2 2 2 Fatty acid desaturase Lipid_DES PF08557.10 PSC67804.1 - 5.3e-11 41.8 0.0 1.3e-10 40.5 0.0 1.7 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) DUF4219 PF13961.6 PSC67804.1 - 1.2e-05 24.8 0.0 2.8e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 PSC67804.1 - 0.037 13.8 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type 5_nucleotid_C PF02872.18 PSC67806.1 - 3.3e-23 82.7 0.0 6.2e-23 81.8 0.0 1.5 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 PSC67806.1 - 6.1e-12 46.5 0.0 9.1e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PGA_cap PF09587.10 PSC67806.1 - 0.00087 18.8 0.4 0.0028 17.1 0.4 1.8 1 1 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap ATG16 PF08614.11 PSC67807.1 - 0.00032 21.0 7.6 0.00032 21.0 7.6 14.2 6 4 8 14 14 14 5 Autophagy protein 16 (ATG16) Transglut_core2 PF13369.6 PSC67808.1 - 1.7e-43 147.9 0.0 2.7e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Transglutaminase-like superfamily TPR_9 PF13371.6 PSC67808.1 - 1.5e-08 34.7 0.2 4.8e-08 33.0 0.2 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat Serglycin PF04360.12 PSC67809.1 - 0.19 11.7 0.1 0.37 10.7 0.1 1.5 1 0 0 1 1 1 0 Serglycin Cellulase PF00150.18 PSC67810.1 - 7e-06 25.7 0.8 1.2e-05 24.9 0.8 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DHC_N1 PF08385.12 PSC67811.1 - 4.7e-144 481.1 0.0 1.1e-143 479.9 0.0 1.7 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 PSC67811.1 - 5e-115 384.8 0.0 1.3e-114 383.5 0.0 1.8 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.7 PSC67811.1 - 1.2e-113 379.4 3.6 1.8e-72 244.1 0.0 3.7 5 1 1 6 6 5 2 Hydrolytic ATP binding site of dynein motor region AAA_8 PF12780.7 PSC67811.1 - 2.6e-102 341.6 0.0 1.7e-101 338.9 0.0 2.4 3 0 0 3 3 3 1 P-loop containing dynein motor region D4 MT PF12777.7 PSC67811.1 - 6.9e-88 295.0 5.6 1.3e-87 294.1 5.6 1.4 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor Dynein_C PF18199.1 PSC67811.1 - 2.2e-86 289.9 0.2 2.2e-86 289.9 0.2 2.0 2 0 0 2 2 2 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 PSC67811.1 - 2.9e-80 268.5 0.4 2.9e-80 268.5 0.4 2.4 2 0 0 2 2 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 PSC67811.1 - 3.4e-69 232.0 0.0 1.7e-63 213.4 0.0 3.7 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_lid_11 PF18198.1 PSC67811.1 - 4.5e-44 150.1 0.0 9.1e-44 149.2 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain DnaJ_C PF01556.18 PSC67811.1 - 6.1e-34 117.2 0.0 1e-33 116.5 0.0 1.4 1 0 0 1 1 1 1 DnaJ C terminal domain Dynein_heavy PF03028.15 PSC67811.1 - 1.5e-33 115.4 0.0 3e-31 108.0 0.0 3.4 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain DnaJ PF00226.31 PSC67811.1 - 2.9e-23 81.8 1.3 9.8e-23 80.1 1.3 2.0 1 0 0 1 1 1 1 DnaJ domain Dynein_AAA_lid PF17852.1 PSC67811.1 - 1.2e-22 80.3 0.1 4.2e-22 78.6 0.1 2.0 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_lid_1 PF17857.1 PSC67811.1 - 3.8e-22 78.4 0.1 3.1e-21 75.4 0.1 2.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 PSC67811.1 - 1.5e-18 67.1 0.0 1.4e-09 38.1 0.0 5.4 4 0 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA PF00004.29 PSC67811.1 - 7.7e-12 45.8 0.0 0.012 16.1 0.0 5.0 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) DnaJ_CXXCXGXG PF00684.19 PSC67811.1 - 3e-09 37.1 20.3 7.3e-09 35.9 20.3 1.7 1 0 0 1 1 1 1 DnaJ central domain AAA_22 PF13401.6 PSC67811.1 - 1.1e-07 32.3 5.2 0.27 11.5 0.0 5.9 8 0 0 8 8 4 2 AAA domain AAA_18 PF13238.6 PSC67811.1 - 3.5e-07 30.8 0.5 0.13 12.8 0.0 4.1 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.6 PSC67811.1 - 6.5e-05 23.4 18.1 0.18 12.1 0.0 7.7 9 0 0 9 9 7 2 AAA ATPase domain RNA_helicase PF00910.22 PSC67811.1 - 0.00012 22.5 0.0 5.6 7.4 0.0 3.9 3 0 0 3 3 3 0 RNA helicase AAA_30 PF13604.6 PSC67811.1 - 0.00019 21.2 0.0 3 7.5 0.0 4.1 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 PSC67811.1 - 0.00036 21.1 0.0 1.2 9.7 0.0 3.6 3 0 0 3 3 2 1 ABC transporter Sigma54_activat PF00158.26 PSC67811.1 - 0.001 18.8 0.0 0.89 9.2 0.0 3.5 3 0 0 3 3 3 1 Sigma-54 interaction domain AAA_33 PF13671.6 PSC67811.1 - 0.0015 18.7 0.3 15 5.8 0.0 4.5 4 0 0 4 4 4 0 AAA domain TsaE PF02367.17 PSC67811.1 - 0.0023 17.9 0.1 4.7 7.2 0.0 4.3 4 0 0 4 4 4 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 PSC67811.1 - 0.0037 17.2 0.1 0.86 9.5 0.0 3.2 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea RsgA_GTPase PF03193.16 PSC67811.1 - 0.0048 16.8 0.0 5.1 7.0 0.0 3.3 3 0 0 3 3 3 0 RsgA GTPase Cytidylate_kin PF02224.18 PSC67811.1 - 0.0062 16.3 0.0 2.4 7.9 0.0 2.8 2 0 0 2 2 2 1 Cytidylate kinase AAA_28 PF13521.6 PSC67811.1 - 0.041 14.1 0.4 42 4.4 0.0 4.3 4 0 0 4 4 3 0 AAA domain Roc PF08477.13 PSC67811.1 - 0.11 12.8 0.0 10 6.4 0.0 3.0 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase PduV-EutP PF10662.9 PSC67811.1 - 0.13 12.0 1.0 2.9 7.7 0.0 3.2 4 0 0 4 4 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.12 PSC67811.1 - 0.27 11.2 1.3 26 4.7 0.0 4.0 3 0 0 3 3 3 0 NACHT domain zinc-ribbons_6 PF07191.12 PSC67811.1 - 0.33 11.0 5.4 0.98 9.5 5.4 1.9 1 0 0 1 1 1 0 zinc-ribbons DUF4061 PF13270.6 PSC67811.1 - 0.41 11.0 2.2 6.3 7.2 0.0 3.7 3 0 0 3 3 2 0 Domain of unknown function (DUF4061) MnmE_helical PF12631.7 PSC67811.1 - 3.9 7.6 6.6 76 3.4 6.6 3.1 1 1 0 1 1 1 0 MnmE helical domain ABC_tran_CTD PF16326.5 PSC67811.1 - 7.3 6.9 11.1 12 6.2 0.5 4.1 2 0 0 2 2 2 0 ABC transporter C-terminal domain TAXi_N PF14543.6 PSC67812.1 - 2.5e-38 132.1 4.5 5e-38 131.1 4.5 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp PF00026.23 PSC67812.1 - 3.4e-28 99.0 0.0 1.1e-26 94.0 0.0 2.1 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 PSC67812.1 - 8.5e-24 84.1 0.1 1.9e-23 83.0 0.0 1.6 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Suf PF05843.14 PSC67812.1 - 6 6.8 6.5 9.3 6.1 6.5 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) WD40 PF00400.32 PSC67813.1 - 2e-47 158.1 20.8 2.5e-08 34.4 0.1 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC67813.1 - 8.5e-09 35.6 0.5 0.13 12.6 0.0 4.8 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 PSC67813.1 - 0.00098 18.3 0.0 0.14 11.2 0.0 2.6 2 2 0 2 2 2 2 Protein of unknown function (DUF1513) WD40_like PF17005.5 PSC67813.1 - 0.0042 16.4 0.0 0.31 10.3 0.0 2.2 2 0 0 2 2 2 1 WD40-like domain Cytochrom_D1 PF02239.16 PSC67813.1 - 0.0062 15.1 0.0 0.78 8.2 0.1 2.1 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.8 PSC67813.1 - 0.01 14.5 7.2 1.4 7.5 0.1 4.4 1 1 4 5 5 5 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 PSC67813.1 - 0.014 14.4 0.1 2.2 7.2 0.0 3.4 2 2 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 PSC67813.1 - 0.067 13.2 0.1 8.3 6.5 0.0 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Fibrinogen_aC PF12160.8 PSC67813.1 - 0.11 12.4 0.0 13 5.7 0.0 3.0 3 0 0 3 3 3 0 Fibrinogen alpha C domain WD40 PF00400.32 PSC67814.1 - 1.4e-46 155.5 22.4 3.8e-08 33.9 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC67814.1 - 6.7e-08 32.7 0.5 0.79 10.1 0.0 4.5 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1513 PF07433.11 PSC67814.1 - 0.002 17.3 0.0 0.2 10.7 0.0 2.8 2 1 0 2 2 2 1 Protein of unknown function (DUF1513) WD40_like PF17005.5 PSC67814.1 - 0.011 15.1 0.0 0.51 9.6 0.0 2.2 2 0 0 2 2 2 0 WD40-like domain Cytochrom_D1 PF02239.16 PSC67814.1 - 0.015 13.9 0.0 1.2 7.5 0.1 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nup160 PF11715.8 PSC67814.1 - 0.036 12.7 6.8 2.1 6.9 0.1 4.2 1 1 4 5 5 5 0 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 PSC67814.1 - 0.045 12.7 0.1 4.2 6.2 0.0 3.1 2 2 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF3446 PF11928.8 PSC67814.1 - 0.11 12.8 3.0 0.33 11.3 3.0 1.8 1 0 0 1 1 1 0 Early growth response N-terminal domain WD40 PF00400.32 PSC67815.1 - 6.4e-48 159.7 23.5 9.2e-08 32.6 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat E1-E2_ATPase PF00122.20 PSC67815.1 - 2e-26 92.6 0.0 5.3e-26 91.2 0.0 1.6 2 0 0 2 2 2 1 E1-E2 ATPase ANAPC4_WD40 PF12894.7 PSC67815.1 - 6.5e-09 36.0 0.5 1.2 9.5 0.0 5.0 1 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PSC67815.1 - 0.001 18.1 0.0 2.2 7.1 0.0 3.7 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 PSC67815.1 - 0.072 11.6 0.0 3.4 6.1 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain WD40_like PF17005.5 PSC67815.1 - 0.073 12.4 0.0 1.4 8.2 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain Nup160 PF11715.8 PSC67815.1 - 0.29 9.7 5.7 5.4 5.5 0.1 3.9 2 1 1 5 5 5 0 Nucleoporin Nup120/160 Iso_dh PF00180.20 PSC67816.1 - 1.2e-65 221.9 0.0 1.3e-36 126.4 0.0 2.1 2 0 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase HMA PF00403.26 PSC67817.1 - 4e-14 52.8 2.3 4.7e-14 52.6 2.3 1.1 1 0 0 1 1 1 1 Heavy-metal-associated domain Pro_Al_protease PF02983.14 PSC67817.1 - 0.023 14.7 2.7 0.028 14.5 2.7 1.1 1 0 0 1 1 1 0 Alpha-lytic protease prodomain Flavodoxin_4 PF12682.7 PSC67817.1 - 0.043 13.5 0.2 0.047 13.4 0.2 1.1 1 0 0 1 1 1 0 Flavodoxin DUF211 PF02680.14 PSC67817.1 - 0.045 13.9 0.0 0.053 13.7 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized ArCR, COG1888 Ribosomal_S7 PF00177.21 PSC67820.1 - 8.3e-37 126.1 1.0 8.3e-37 126.1 1.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S7p/S5e GFA PF04828.14 PSC67820.1 - 3.5e-05 24.1 3.3 3.5e-05 24.1 3.3 2.1 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Ribosomal_L6e PF01159.19 PSC67820.1 - 0.058 13.9 0.1 0.1 13.1 0.1 1.4 1 0 0 1 1 1 0 Ribosomal protein L6e PEP-utilisers_N PF05524.13 PSC67820.1 - 0.28 11.4 3.7 0.31 11.2 2.3 1.7 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal Robl_LC7 PF03259.17 PSC67824.1 - 7.4e-22 76.9 0.6 3.1e-21 74.9 0.1 2.2 2 0 0 2 2 2 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 PSC67824.1 - 0.049 13.5 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Ragulator complex protein LAMTOR5 Iso_dh PF00180.20 PSC67826.1 - 8.4e-55 186.3 0.0 1.7e-33 116.2 0.0 2.0 2 0 0 2 2 2 2 Isocitrate/isopropylmalate dehydrogenase Mg-por_mtran_C PF07109.11 PSC67827.1 - 2.7e-34 117.4 0.0 8e-34 115.9 0.0 1.9 1 0 0 1 1 1 1 Magnesium-protoporphyrin IX methyltransferase C-terminus Methyltransf_25 PF13649.6 PSC67827.1 - 4.9e-11 43.2 0.2 8e-10 39.3 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC67827.1 - 1.1e-10 41.5 0.0 3.9e-10 39.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC67827.1 - 9.3e-08 32.7 0.0 5.4e-07 30.3 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC67827.1 - 4e-07 30.6 0.1 0.00014 22.4 0.0 3.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC67827.1 - 0.00031 20.5 0.0 0.0019 18.0 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 PSC67827.1 - 0.0065 15.9 0.4 0.023 14.1 0.1 2.1 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 PSC67827.1 - 0.024 14.6 0.5 0.21 11.6 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Arm PF00514.23 PSC67827.1 - 0.035 14.1 8.1 0.065 13.3 0.0 4.7 5 1 0 5 5 5 0 Armadillo/beta-catenin-like repeat MTS PF05175.14 PSC67827.1 - 0.082 12.4 1.1 0.17 11.4 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain CMAS PF02353.20 PSC67827.1 - 0.096 12.0 0.0 0.23 10.7 0.0 1.7 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Cellulase PF00150.18 PSC67829.1 - 4.9e-06 26.2 0.5 8.8e-06 25.3 0.5 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Fe-S_biosyn PF01521.20 PSC67830.1 - 6.7e-22 77.8 0.0 8.2e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Rer1 PF03248.13 PSC67831.1 - 3.3e-67 225.5 6.1 4.3e-67 225.1 6.1 1.1 1 0 0 1 1 1 1 Rer1 family JAB PF01398.21 PSC67832.1 - 5.1e-09 36.1 0.0 1.2e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 PSC67832.1 - 3e-08 33.5 0.1 1.1e-07 31.7 0.1 2.0 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Myb_DNA-binding PF00249.31 PSC67832.1 - 6.9e-08 32.6 0.1 1.5e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC67832.1 - 0.019 15.2 0.4 0.041 14.1 0.1 1.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PSC67832.1 - 0.02 14.8 0.1 0.04 13.8 0.1 1.4 1 0 0 1 1 1 0 Myb DNA-binding like JAB PF01398.21 PSC67833.1 - 5e-09 36.2 0.0 1.2e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 PSC67833.1 - 2.9e-08 33.5 0.1 1.1e-07 31.7 0.1 2.0 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain Myb_DNA-binding PF00249.31 PSC67833.1 - 7.1e-08 32.5 0.1 1.5e-07 31.5 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC67833.1 - 0.019 15.2 0.4 0.041 14.1 0.1 1.7 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PSC67833.1 - 0.02 14.7 0.1 0.04 13.8 0.1 1.4 1 0 0 1 1 1 0 Myb DNA-binding like Nt_Gln_amidase PF09764.9 PSC67834.1 - 1.2e-51 175.0 0.0 2.4e-51 174.0 0.0 1.4 1 0 0 1 1 1 1 N-terminal glutamine amidase GATA PF00320.27 PSC67834.1 - 8.6e-11 41.3 3.9 8.6e-11 41.3 3.9 2.0 3 0 0 3 3 3 1 GATA zinc finger Gln_deamidase_2 PF18626.1 PSC67834.1 - 0.0076 16.5 1.2 0.013 15.8 0.0 1.9 2 0 0 2 2 2 1 Glutaminase UPF0560 PF10577.9 PSC67834.1 - 0.047 12.2 12.3 0.097 11.2 12.3 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 LAG1-DNAbind PF09271.11 PSC67834.1 - 0.052 14.2 2.7 0.12 13.0 2.7 1.5 1 0 0 1 1 1 0 LAG1, DNA binding Glyco_transf_90 PF05686.12 PSC67835.1 - 6.5e-24 84.6 0.0 2.9e-23 82.4 0.1 1.9 2 1 0 2 2 2 1 Glycosyl transferase family 90 DnaJ PF00226.31 PSC67835.1 - 1.4e-11 44.4 0.1 3.9e-11 42.9 0.1 1.8 1 0 0 1 1 1 1 DnaJ domain TFIIA PF03153.13 PSC67835.1 - 0.34 10.9 17.7 0.56 10.2 17.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SelP_N PF04592.14 PSC67835.1 - 5 6.5 10.1 9.2 5.6 10.1 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Lactamase_B_2 PF12706.7 PSC67836.1 - 9.8e-11 41.5 0.3 0.00012 21.7 0.0 2.8 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PSC67836.1 - 1.2e-09 38.5 0.2 2.5e-09 37.4 0.2 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily SAP PF02037.27 PSC67836.1 - 5.5e-08 32.4 0.0 1e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 SAP domain Lactamase_B_4 PF13691.6 PSC67836.1 - 0.0053 16.4 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 tRNase Z endonuclease DUF4518 PF15008.6 PSC67836.1 - 0.13 11.4 0.5 0.2 10.8 0.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) Roughex PF06020.11 PSC67836.1 - 1.7 7.7 9.2 3.8 6.5 9.2 1.6 1 0 0 1 1 1 0 Drosophila roughex protein Abhydrolase_6 PF12697.7 PSC67837.1 - 8.3e-16 59.3 17.9 8.3e-16 59.3 17.9 3.0 2 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PSC67837.1 - 9.6e-12 45.1 0.0 4.6e-10 39.6 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC67837.1 - 1.3e-09 37.7 0.0 5.4e-09 35.7 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 RNA_pol_3_Rpc31 PF11705.8 PSC67837.1 - 2.3e-09 37.9 8.7 2.2e-06 28.1 5.7 3.0 2 1 1 3 3 3 2 DNA-directed RNA polymerase III subunit Rpc31 Ser_hydrolase PF06821.13 PSC67837.1 - 0.0013 18.6 0.1 0.0057 16.5 0.0 2.0 2 0 0 2 2 2 1 Serine hydrolase AXE1 PF05448.12 PSC67837.1 - 0.18 10.4 0.0 0.28 9.8 0.0 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) TMEM247 PF15444.6 PSC67837.1 - 0.31 11.1 1.5 0.64 10.0 1.5 1.4 1 0 0 1 1 1 0 Transmembrane protein 247 GSDH PF07995.11 PSC67838.1 - 0.00086 18.7 0.1 0.0086 15.4 0.0 2.3 2 1 0 2 2 2 1 Glucose / Sorbosone dehydrogenase SGL PF08450.12 PSC67838.1 - 0.0087 15.7 0.5 0.16 11.5 0.0 2.5 1 1 1 2 2 2 2 SMP-30/Gluconolactonase/LRE-like region 2OG-FeII_Oxy_3 PF13640.6 PSC67839.1 - 1.9e-06 28.7 0.1 7.1e-06 26.8 0.1 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Acetyltransf_10 PF13673.7 PSC67839.1 - 9.2e-06 25.6 0.0 1.4e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PSC67839.1 - 1e-05 25.7 0.0 6.8e-05 23.1 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family 2OG-FeII_Oxy_4 PF13661.6 PSC67839.1 - 8.1e-05 23.2 0.1 0.00016 22.3 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Acetyltransf_7 PF13508.7 PSC67839.1 - 0.0013 19.2 0.0 0.0029 18.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PSC67839.1 - 0.036 14.2 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 PSC67839.1 - 0.069 13.2 0.0 0.12 12.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC67839.1 - 0.09 12.8 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_13 PF13880.6 PSC67839.1 - 0.099 12.6 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase PNRC PF15365.6 PSC67840.1 - 5.1e-07 29.3 2.3 5.1e-07 29.3 2.3 2.5 2 0 0 2 2 2 1 Proline-rich nuclear receptor coactivator motif DEAD PF00270.29 PSC67841.1 - 2.5e-43 147.9 0.2 3.6e-43 147.4 0.2 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC67841.1 - 4.6e-28 97.8 0.3 2.2e-27 95.6 0.3 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC67841.1 - 0.00024 21.1 0.0 0.00041 20.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 PSC67841.1 - 0.0039 16.4 0.1 0.006 15.8 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase CMS1 PF14617.6 PSC67841.1 - 0.044 13.1 0.1 0.082 12.2 0.1 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit TatC PF00902.18 PSC67842.1 - 1.2e-57 195.1 12.3 1.5e-57 194.8 12.3 1.1 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) Ribonuclease_T2 PF00445.18 PSC67843.1 - 2.1e-32 112.9 0.0 8.9e-32 110.8 0.0 1.8 1 1 0 1 1 1 1 Ribonuclease T2 family Thioredoxin PF00085.20 PSC67844.1 - 0.0071 16.3 0.0 0.012 15.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin EGF_CA PF07645.15 PSC67845.1 - 1.3e-08 34.9 8.3 3.1e-08 33.7 8.3 1.6 1 0 0 1 1 1 1 Calcium-binding EGF domain EGF_3 PF12947.7 PSC67845.1 - 1.9e-05 24.7 9.6 4.6e-05 23.5 9.6 1.6 1 0 0 1 1 1 1 EGF domain PAN_4 PF14295.6 PSC67845.1 - 0.00014 21.7 0.4 0.00035 20.4 0.4 1.6 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 PSC67845.1 - 0.00027 20.8 2.1 0.00056 19.8 2.1 1.4 1 0 0 1 1 1 1 PAN domain EGF PF00008.27 PSC67845.1 - 0.00065 20.0 9.8 0.0015 18.8 9.8 1.7 1 0 0 1 1 1 1 EGF-like domain Cellulase PF00150.18 PSC67845.1 - 0.002 17.6 0.0 0.016 14.7 0.0 2.0 1 1 1 2 2 2 1 Cellulase (glycosyl hydrolase family 5) FXa_inhibition PF14670.6 PSC67845.1 - 0.01 16.1 8.4 0.021 15.1 8.4 1.5 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site SET PF00856.28 PSC67845.1 - 0.39 11.1 0.0 0.39 11.1 0.0 4.1 4 1 0 5 5 5 0 SET domain cEGF PF12662.7 PSC67845.1 - 0.64 10.0 4.9 1.5 8.9 4.9 1.6 1 0 0 1 1 1 0 Complement Clr-like EGF-like hEGF PF12661.7 PSC67845.1 - 0.85 10.4 7.3 1.9 9.2 7.3 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF FtsJ PF01728.19 PSC67846.1 - 2.7e-66 223.0 0.0 3.2e-66 222.8 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase PRIMA1 PF16101.5 PSC67846.1 - 7.9 6.5 9.3 3.6 7.7 3.7 2.2 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 FtsJ PF01728.19 PSC67847.1 - 2.8e-66 223.0 0.0 3.4e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase PRIMA1 PF16101.5 PSC67847.1 - 4.9 7.2 9.3 3.9 7.5 3.8 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 FtsJ PF01728.19 PSC67848.1 - 2.8e-66 223.0 0.0 3.4e-66 222.7 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase PRIMA1 PF16101.5 PSC67848.1 - 4.9 7.2 9.3 3.9 7.5 3.8 2.3 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Pkinase PF00069.25 PSC67849.1 - 3.1e-132 439.8 0.0 1.5e-65 221.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC67849.1 - 1.7e-57 194.7 0.0 5.8e-29 101.2 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase CbiQ PF02361.16 PSC67849.1 - 8.8e-19 68.0 2.4 1.4e-18 67.4 2.4 1.3 1 0 0 1 1 1 1 Cobalt transport protein Kinase-like PF14531.6 PSC67849.1 - 0.00012 21.6 0.0 0.22 10.8 0.0 2.8 3 0 0 3 3 3 2 Kinase-like Pkinase_fungal PF17667.1 PSC67849.1 - 0.011 14.6 0.0 3.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Fungal protein kinase Hairy_orange PF07527.13 PSC67850.1 - 0.15 12.3 0.1 0.84 9.9 0.0 2.2 2 0 0 2 2 2 0 Hairy Orange PRK PF00485.18 PSC67851.1 - 4.5e-05 23.3 0.0 0.00027 20.7 0.0 2.1 2 1 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 PSC67851.1 - 0.015 15.6 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain MobB PF03205.14 PSC67851.1 - 0.021 14.7 0.0 0.37 10.7 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 PSC67851.1 - 0.032 14.8 0.0 0.055 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 PSC67851.1 - 0.087 12.1 0.0 0.094 11.9 0.0 1.1 1 0 0 1 1 1 0 KAP family P-loop domain MeaB PF03308.16 PSC67851.1 - 0.11 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC1 PF03109.16 PSC67852.1 - 2.7e-26 92.1 0.0 5.4e-26 91.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family SUIM_assoc PF16619.5 PSC67854.1 - 6 7.0 7.9 17 5.6 7.9 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Fe-S_biosyn PF01521.20 PSC67855.1 - 6.7e-22 77.8 0.0 8.2e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis zf-Tim10_DDP PF02953.15 PSC67856.1 - 3.1e-25 87.6 4.3 3.8e-25 87.3 4.3 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF4568 PF15132.6 PSC67856.1 - 0.043 13.2 0.1 0.048 13.0 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4568) tRNA_bind PF01588.20 PSC67857.1 - 1e-29 102.5 0.1 1.6e-29 101.8 0.1 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_2 PF13410.6 PSC67857.1 - 4e-06 26.7 0.3 9.2e-06 25.6 0.3 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PSC67857.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain TPPII_N PF12583.8 PSC67857.1 - 0.29 11.7 11.6 0.24 12.0 10.2 1.6 1 1 0 1 1 1 0 Tripeptidyl peptidase II N terminal CX9C PF16860.5 PSC67858.1 - 0.00039 20.4 0.2 0.00067 19.6 0.2 1.3 1 0 0 1 1 1 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 PSC67858.1 - 0.00071 19.6 0.9 0.0012 18.9 0.9 1.4 1 0 0 1 1 1 1 CHCH domain ParB_C PF18064.1 PSC67858.1 - 0.062 13.5 0.2 0.062 13.5 0.2 2.1 2 0 0 2 2 2 0 Centromere-binding protein ParB C-terminal Cmc1 PF08583.10 PSC67858.1 - 0.16 12.0 0.8 0.32 11.1 0.8 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like DivIC PF04977.15 PSC67858.1 - 7.2 6.5 8.2 4.5 7.1 0.1 2.9 3 1 0 3 3 3 0 Septum formation initiator DUF3223 PF11523.8 PSC67859.1 - 0.0044 17.8 0.0 0.0082 17.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3223) K_channel_TID PF07941.11 PSC67859.1 - 0.041 14.3 1.7 0.041 14.3 1.7 2.6 3 0 0 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain SWIB PF02201.18 PSC67860.1 - 1.2e-16 60.3 0.0 2.3e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain Spore_II_R PF09551.10 PSC67860.1 - 0.83 10.1 5.4 1.8 9.0 5.4 1.6 1 0 0 1 1 1 0 Stage II sporulation protein R (spore_II_R) DUF4769 PF15992.5 PSC67860.1 - 1.4 8.6 6.1 5.5 6.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4769) NUC153 PF08159.12 PSC67861.1 - 1.4e-15 56.7 10.1 2e-09 37.1 0.3 3.5 3 0 0 3 3 3 3 NUC153 domain Astro_capsid_p PF12226.8 PSC67861.1 - 0.0029 16.8 7.5 0.0029 16.8 7.5 3.0 4 0 0 4 4 4 1 Turkey astrovirus capsid protein Cytomega_UL84 PF06284.11 PSC67861.1 - 0.82 8.1 7.6 2.7 6.3 7.6 1.9 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein ClpS PF02617.17 PSC67862.1 - 2.8e-16 59.1 0.2 2.8e-16 59.1 0.2 2.0 2 0 0 2 2 2 1 ATP-dependent Clp protease adaptor protein ClpS Peptidase_S28 PF05577.12 PSC67863.1 - 2.5e-67 227.6 0.0 3.7e-67 227.0 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 60KD_IMP PF02096.20 PSC67863.1 - 1.1e-54 184.8 0.6 1.6e-54 184.3 0.6 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Hydrolase_4 PF12146.8 PSC67863.1 - 2.5e-06 26.9 0.3 7.2e-06 25.4 0.1 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 PSC67863.1 - 0.00043 19.8 0.0 0.00043 19.8 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 PSC67863.1 - 0.001 18.8 0.1 0.0025 17.5 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 PSC67863.1 - 0.0044 16.7 0.4 0.012 15.3 0.4 1.7 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 PSC67863.1 - 0.065 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.12 PSC67863.1 - 0.13 12.2 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2920 PF11144.8 PSC67863.1 - 0.16 11.1 0.3 0.41 9.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Collagen_mid PF15984.5 PSC67863.1 - 2.9 7.6 8.3 0.3 10.8 2.7 2.0 2 0 0 2 2 2 0 Bacterial collagen, middle region Peptidase_S28 PF05577.12 PSC67864.1 - 2.2e-67 227.7 0.0 3.4e-67 227.1 0.0 1.3 1 0 0 1 1 1 1 Serine carboxypeptidase S28 60KD_IMP PF02096.20 PSC67864.1 - 1.1e-54 184.9 0.6 1.5e-54 184.4 0.6 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein Hydrolase_4 PF12146.8 PSC67864.1 - 2.4e-06 27.0 0.3 6.8e-06 25.5 0.1 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 PSC67864.1 - 0.00041 19.9 0.0 0.00041 19.9 0.0 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 PSC67864.1 - 0.0011 18.7 0.1 0.0023 17.6 0.1 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 PSC67864.1 - 0.004 16.8 0.4 0.011 15.4 0.4 1.7 1 0 0 1 1 1 1 Putative esterase PGAP1 PF07819.13 PSC67864.1 - 0.061 13.0 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein UPF0227 PF05728.12 PSC67864.1 - 0.12 12.3 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF2920 PF11144.8 PSC67864.1 - 0.15 11.2 0.3 0.39 9.8 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) Collagen_mid PF15984.5 PSC67864.1 - 2.9 7.6 9.0 0.29 10.9 2.7 2.2 2 0 0 2 2 2 0 Bacterial collagen, middle region Acetyltransf_1 PF00583.25 PSC67865.1 - 1.3e-08 35.1 0.0 7.4e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family 2OG-FeII_Oxy_3 PF13640.6 PSC67865.1 - 2.2e-06 28.4 0.1 8.5e-06 26.6 0.1 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Acetyltransf_10 PF13673.7 PSC67865.1 - 5.7e-06 26.3 0.0 1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain 2OG-FeII_Oxy_4 PF13661.6 PSC67865.1 - 9.7e-05 23.0 0.1 0.00019 22.1 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Acetyltransf_7 PF13508.7 PSC67865.1 - 0.00051 20.4 0.0 0.0011 19.3 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PSC67865.1 - 0.023 14.8 0.0 0.047 13.8 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PSC67865.1 - 0.031 14.4 0.0 0.067 13.3 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 PSC67865.1 - 0.05 14.3 0.0 0.14 12.8 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC67865.1 - 0.089 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_13 PF13880.6 PSC67865.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase TRM PF02005.16 PSC67866.1 - 9.1e-31 107.4 0.0 1.3e-18 67.3 0.0 3.2 3 0 0 3 3 3 3 N2,N2-dimethylguanosine tRNA methyltransferase DUF5327 PF17261.2 PSC67866.1 - 0.048 14.4 1.3 0.048 14.4 1.3 2.5 3 0 0 3 3 3 0 Family of unknown function (DUF5327) Pkinase PF00069.25 PSC67867.1 - 3.4e-62 210.2 0.0 4.7e-62 209.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC67867.1 - 6.3e-43 146.9 0.0 9.1e-43 146.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Rab3-GTPase_cat PF13890.6 PSC67867.1 - 2.9e-41 140.8 0.0 5.2e-41 140.0 0.0 1.4 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit ubiquitin PF00240.23 PSC67867.1 - 1.3e-20 72.9 0.0 1.7e-13 50.1 0.0 2.6 2 0 0 2 2 2 2 Ubiquitin family Ubiquitin_2 PF14560.6 PSC67867.1 - 2.5e-05 24.6 0.0 0.0073 16.7 0.0 2.7 3 0 0 3 3 3 1 Ubiquitin-like domain Kinase-like PF14531.6 PSC67867.1 - 9.6e-05 21.8 0.0 0.00015 21.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like PAP_fibrillin PF04755.12 PSC67867.1 - 0.0087 16.0 0.1 0.048 13.6 0.0 2.1 2 0 0 2 2 2 1 PAP_fibrillin Rad60-SLD PF11976.8 PSC67867.1 - 0.028 14.2 0.0 0.054 13.3 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Seadorna_VP7 PF07387.11 PSC67867.1 - 0.24 10.4 0.1 0.37 9.8 0.1 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Mito_carr PF00153.27 PSC67868.1 - 1e-67 224.1 4.3 3.2e-24 84.7 0.1 3.4 4 0 0 4 4 4 3 Mitochondrial carrier protein Calponin PF00402.18 PSC67868.1 - 0.041 13.5 0.2 0.11 12.1 0.2 1.7 1 0 0 1 1 1 0 Calponin family repeat Mg_trans_NIPA PF05653.14 PSC67869.1 - 3.1e-11 42.9 2.9 3.1e-11 42.9 2.9 2.5 3 0 0 3 3 3 1 Magnesium transporter NIPA EamA PF00892.20 PSC67869.1 - 0.0014 18.8 1.1 0.0014 18.8 1.1 4.4 3 1 1 4 4 4 1 EamA-like transporter family Mg_trans_NIPA PF05653.14 PSC67870.1 - 3.1e-11 42.9 2.9 3.1e-11 42.9 2.9 2.5 3 0 0 3 3 3 1 Magnesium transporter NIPA EamA PF00892.20 PSC67870.1 - 0.0014 18.8 1.1 0.0014 18.8 1.1 4.5 3 1 1 4 4 4 1 EamA-like transporter family Methyltransf_16 PF10294.9 PSC67872.1 - 8.2e-08 32.2 0.0 0.001 18.9 0.0 2.4 2 0 0 2 2 2 2 Lysine methyltransferase PrmA PF06325.13 PSC67872.1 - 7.8e-06 25.5 0.7 1.3e-05 24.8 0.1 1.5 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 PSC67872.1 - 0.00021 20.9 0.1 0.00041 19.9 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 PSC67872.1 - 0.00099 18.9 0.1 0.00099 18.9 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC67872.1 - 0.0038 17.9 0.4 0.0089 16.7 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain SR-25 PF10500.9 PSC67872.1 - 0.0039 16.8 5.0 0.0056 16.3 5.0 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF755 PF05501.11 PSC67872.1 - 0.006 16.8 7.3 0.01 16.1 7.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF755) Rrn6 PF10214.9 PSC67872.1 - 0.011 14.3 7.4 0.014 13.9 7.4 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Methyltransf_23 PF13489.6 PSC67872.1 - 0.018 14.9 1.1 0.028 14.3 1.1 1.5 1 1 0 1 1 1 0 Methyltransferase domain CNDH2_M PF16869.5 PSC67872.1 - 0.018 15.7 0.4 0.035 14.8 0.4 1.5 1 0 0 1 1 1 0 PF16858 TFIIA PF03153.13 PSC67872.1 - 0.051 13.6 8.0 0.063 13.3 8.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4770 PF15994.5 PSC67872.1 - 0.09 13.0 3.8 0.15 12.2 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) GREB1 PF15782.5 PSC67872.1 - 0.14 9.3 0.7 0.17 9.0 0.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Spt20 PF12090.8 PSC67872.1 - 0.18 11.4 13.2 0.25 10.9 13.2 1.1 1 0 0 1 1 1 0 Spt20 family Ku_N PF03731.15 PSC67872.1 - 0.29 10.9 3.0 0.43 10.3 3.0 1.1 1 0 0 1 1 1 0 Ku70/Ku80 N-terminal alpha/beta domain ARF7EP_C PF14949.6 PSC67872.1 - 0.66 10.6 5.1 1.7 9.3 3.3 2.0 2 0 0 2 2 2 0 ARF7 effector protein C-terminus DUF2722 PF10846.8 PSC67872.1 - 0.83 8.5 12.7 1.1 8.1 12.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 PSC67872.1 - 1 8.1 2.2 1.3 7.8 2.2 1.1 1 0 0 1 1 1 0 Presenilin UPF0560 PF10577.9 PSC67872.1 - 1 7.8 6.6 1.4 7.3 6.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TERB2 PF15101.6 PSC67872.1 - 2 8.4 6.6 3.4 7.7 6.6 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Peptidase_M11 PF05548.11 PSC67873.1 - 5.8e-17 61.8 6.4 9.6e-17 61.1 6.4 1.3 1 0 0 1 1 1 1 Gametolysin peptidase M11 TFIIA PF03153.13 PSC67873.1 - 0.07 13.1 5.6 0.1 12.6 5.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 PSC67873.1 - 4.5 6.8 10.4 7.5 6.1 10.4 1.2 1 0 0 1 1 1 0 Spt20 family OCRE PF17780.1 PSC67874.1 - 1.4e-08 34.6 0.3 2.8e-08 33.6 0.3 1.5 1 0 0 1 1 1 1 OCRE domain SWIM PF04434.17 PSC67876.1 - 3.9e-06 26.4 0.4 6.5e-06 25.7 0.4 1.4 1 0 0 1 1 1 1 SWIM zinc finger SelK_SelG PF10961.8 PSC67877.1 - 1.1e-14 54.7 1.8 1.4e-14 54.4 1.8 1.1 1 0 0 1 1 1 1 Selenoprotein SelK_SelG WD40 PF00400.32 PSC67878.1 - 2e-11 44.2 0.0 8.1e-07 29.6 0.1 4.4 4 0 0 4 4 4 1 WD domain, G-beta repeat TPR_11 PF13414.6 PSC67878.1 - 7.3e-05 22.4 0.4 0.004 16.8 0.1 2.5 2 0 0 2 2 2 1 TPR repeat ANAPC4_WD40 PF12894.7 PSC67878.1 - 0.0044 17.3 0.0 0.051 13.9 0.0 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain TPR_17 PF13431.6 PSC67878.1 - 0.015 15.7 1.0 2.1 8.9 0.1 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF5401 PF17380.2 PSC67878.1 - 2.2 6.2 11.8 3.4 5.6 11.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Ribosomal_L9_C PF03948.14 PSC67879.1 - 5.9e-07 29.9 0.0 6.6e-07 29.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Peptidase_S9 PF00326.21 PSC67881.1 - 9.2e-36 123.3 0.0 2.4e-35 122.0 0.0 1.7 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 PSC67881.1 - 3.1e-26 92.1 0.0 1.6e-14 53.5 0.0 2.8 2 1 0 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain Hydrolase_4 PF12146.8 PSC67881.1 - 0.065 12.5 0.3 0.16 11.2 0.0 1.8 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Macoilin PF09726.9 PSC67881.1 - 5.3 5.5 10.6 9.3 4.7 10.6 1.3 1 0 0 1 1 1 0 Macoilin family Metallophos PF00149.28 PSC67882.1 - 8.5e-08 32.9 0.0 2.1e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PSC67882.1 - 1.1e-06 28.9 0.1 0.0019 18.4 0.0 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain DEAD PF00270.29 PSC67883.1 - 8.7e-15 54.9 0.0 1.6e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC67883.1 - 3.9e-06 27.2 0.1 7.5e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC67883.1 - 6.7e-06 26.2 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit WW PF00397.26 PSC67883.1 - 0.00087 19.3 0.1 0.0022 18.0 0.1 1.8 1 0 0 1 1 1 1 WW domain QWRF PF04484.12 PSC67883.1 - 1.8 8.2 3.8 4.5 6.9 3.8 1.6 1 0 0 1 1 1 0 QWRF family Trypsin PF00089.26 PSC67884.1 - 2.2e-33 115.9 1.5 1.4e-17 64.3 0.8 3.0 1 1 1 2 2 2 2 Trypsin DUF316 PF03761.15 PSC67884.1 - 7.8e-05 22.4 0.0 0.00015 21.5 0.0 1.4 1 0 0 1 1 1 1 Chymotrypsin family Peptidase-S1 Trypsin_2 PF13365.6 PSC67884.1 - 0.0015 19.4 0.2 0.011 16.7 0.2 2.2 1 1 0 1 1 1 1 Trypsin-like peptidase domain Histone PF00125.24 PSC67885.1 - 2.9e-54 183.0 1.9 3.2e-54 182.8 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 PSC67885.1 - 0.00013 22.5 1.7 0.00016 22.2 1.7 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 PSC67885.1 - 0.00045 20.5 0.0 0.00069 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 PSC67885.1 - 0.00049 20.2 0.5 0.00074 19.6 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 PSC67885.1 - 0.0052 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PSC67885.1 - 0.016 15.3 0.1 0.031 14.3 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit PP2C PF00481.21 PSC67886.1 - 3.1e-52 177.8 0.0 4.3e-52 177.3 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C Trypsin PF00089.26 PSC67886.1 - 1.6e-42 145.8 0.0 2.8e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 Trypsin PP2C_2 PF13672.6 PSC67886.1 - 2.3e-07 30.6 0.1 4.9e-07 29.6 0.1 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C Trypsin_2 PF13365.6 PSC67886.1 - 4.6e-05 24.3 0.1 0.00024 22.0 0.0 2.2 2 0 0 2 2 2 1 Trypsin-like peptidase domain ADD_DNMT3 PF17980.1 PSC67887.1 - 0.45 10.5 4.4 2 8.5 4.4 2.1 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 SecA_DEAD PF07517.14 PSC67888.1 - 2.5e-98 329.0 0.0 4.3e-98 328.2 0.0 1.4 1 0 0 1 1 1 1 SecA DEAD-like domain SecA_SW PF07516.13 PSC67888.1 - 4.4e-17 62.8 0.0 3.8e-16 59.7 0.0 2.3 1 1 0 1 1 1 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 PSC67888.1 - 5.5e-10 39.9 0.0 1.2e-09 38.8 0.0 1.5 1 0 0 1 1 1 1 SecA preprotein cross-linking domain DEAD PF00270.29 PSC67888.1 - 0.00051 19.9 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC67888.1 - 0.11 12.8 0.0 4.8 7.6 0.0 2.4 2 0 0 2 2 2 0 Helicase conserved C-terminal domain CoA_binding PF02629.19 PSC67889.1 - 9.8e-30 103.1 0.3 9.8e-30 103.1 0.3 2.1 3 1 0 3 3 3 1 CoA binding domain Ligase_CoA PF00549.19 PSC67889.1 - 2.5e-23 82.6 0.3 4.3e-23 81.8 0.3 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 PSC67889.1 - 1.8e-11 44.0 0.0 3.5e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Succinyl-CoA ligase like flavodoxin domain N_formyltrans_C PF18216.1 PSC67889.1 - 0.13 12.0 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 N-formyltransferase dimerization C-terminal domain rve PF00665.26 PSC67890.1 - 2.4e-19 69.7 0.0 5.2e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC67890.1 - 0.0032 17.2 0.1 0.0084 15.9 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain Rieske PF00355.26 PSC67891.1 - 2.3e-11 43.5 0.1 3e-11 43.1 0.1 1.2 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain CytB6-F_Fe-S PF08802.10 PSC67891.1 - 1.7e-05 24.7 2.6 3.4e-05 23.8 2.6 1.5 1 0 0 1 1 1 1 Cytochrome B6-F complex Fe-S subunit WHAMM-JMY_N PF15920.5 PSC67891.1 - 0.012 15.5 0.2 0.019 14.8 0.2 1.3 1 0 0 1 1 1 0 N-terminal of Junction-mediating and WASP homolog-associated DUF4588 PF15251.6 PSC67892.1 - 0.0032 17.3 1.8 0.0032 17.3 1.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4588) Cu_bind_like PF02298.17 PSC67893.1 - 4.6e-06 26.6 0.0 6.1e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Plastocyanin-like domain SoxE PF06525.11 PSC67893.1 - 0.016 14.7 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Sulfocyanin (SoxE) domain Methyltransf_11 PF08241.12 PSC67895.1 - 2.5e-10 40.9 0.1 4.5e-10 40.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC67895.1 - 3.8e-10 40.3 0.1 7.5e-10 39.4 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC67895.1 - 1.3e-07 31.6 0.0 2.1e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC67895.1 - 6.6e-06 26.8 0.0 1.7e-05 25.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC67895.1 - 1.2e-05 25.1 0.0 2.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC67895.1 - 1.8e-05 24.2 0.0 2.7e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PKD PF00801.20 PSC67896.1 - 0.015 15.2 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 0 PKD domain UPF0004 PF00919.20 PSC67897.1 - 4.1e-29 100.5 0.1 5.8e-29 100.0 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 CLP1_P PF16575.5 PSC67897.1 - 0.016 15.0 0.0 0.02 14.7 0.0 1.2 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Radical_SAM PF04055.21 PSC67897.1 - 0.036 14.4 2.9 1 9.7 2.2 2.3 2 0 0 2 2 2 0 Radical SAM superfamily DLH PF01738.18 PSC67897.1 - 0.04 13.5 0.0 0.058 12.9 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family Voldacs PF03517.13 PSC67898.1 - 2e-22 79.8 0.2 8.3e-22 77.8 0.0 1.8 2 0 0 2 2 2 1 Regulator of volume decrease after cellular swelling BBL5 PF07289.11 PSC67898.1 - 0.0021 17.2 0.0 0.0028 16.8 0.0 1.1 1 0 0 1 1 1 1 Bardet-Biedl syndrome 5 protein FliX PF10768.9 PSC67899.1 - 0.052 14.1 0.8 0.13 12.8 0.8 1.5 1 0 0 1 1 1 0 Class II flagellar assembly regulator SesA PF17107.5 PSC67899.1 - 0.11 12.6 0.1 0.18 12.0 0.1 1.3 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases KinB_sensor PF16767.5 PSC67899.1 - 0.14 12.6 0.2 0.25 11.8 0.2 1.5 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB IPPT PF01715.17 PSC67902.1 - 3.5e-53 180.8 0.0 5.2e-53 180.2 0.0 1.2 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 PSC67902.1 - 4.3e-07 29.5 0.0 7.7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 Isopentenyl transferase AAA_33 PF13671.6 PSC67902.1 - 0.03 14.5 0.0 0.13 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 PSC67902.1 - 0.17 12.4 0.1 2.8 8.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain RrnaAD PF00398.20 PSC67903.1 - 2.9e-37 128.2 0.0 5.6e-37 127.3 0.0 1.4 1 1 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 PSC67903.1 - 0.0052 17.5 0.4 0.017 15.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain DUF2201_N PF13203.6 PSC67903.1 - 0.038 13.6 3.1 0.065 12.8 3.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Methyltransf_11 PF08241.12 PSC67903.1 - 0.097 13.3 0.0 0.29 11.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 PSC67903.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MOR2-PAG1_mid PF14228.6 PSC67904.1 - 6e-148 494.4 1.0 4.9e-52 176.8 0.0 4.2 3 1 1 4 4 4 4 Cell morphogenesis central region MOR2-PAG1_N PF14222.6 PSC67904.1 - 2.1e-78 264.7 0.0 2.9e-78 264.2 0.0 1.2 1 0 0 1 1 1 1 Cell morphogenesis N-terminal MOR2-PAG1_C PF14225.6 PSC67904.1 - 1.3e-10 41.6 0.0 6.6e-06 26.2 0.0 3.1 4 0 0 4 4 4 2 Cell morphogenesis C-terminal HeLo PF14479.6 PSC67904.1 - 0.12 12.2 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Prion-inhibition and propagation JmjC PF02373.22 PSC67905.1 - 5.2e-09 36.5 0.0 5.2e-09 36.5 0.0 2.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 PSC67905.1 - 0.079 12.7 2.6 0.12 12.1 0.0 2.4 2 0 0 2 2 2 0 Cupin-like domain Cupin_2 PF07883.11 PSC67905.1 - 0.48 10.2 0.0 0.48 10.2 0.0 3.4 4 0 0 4 4 4 0 Cupin domain F-box-like PF12937.7 PSC67906.1 - 0.0001 22.1 0.4 0.00048 20.0 0.4 2.2 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 PSC67906.1 - 0.0036 17.7 5.7 48 4.6 0.1 7.0 6 1 1 7 7 7 1 Leucine Rich repeats (2 copies) TBPIP PF07106.13 PSC67907.1 - 1.3e-09 37.8 0.1 2.8e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 TBPIP/Hop2 winged helix domain LZ3wCH PF18517.1 PSC67907.1 - 0.00013 22.0 0.5 0.00031 20.8 0.0 2.0 2 0 0 2 2 2 1 Leucine zipper with capping helix domain DASH_Spc34 PF08657.10 PSC67907.1 - 0.029 14.2 0.4 0.038 13.8 0.4 1.1 1 0 0 1 1 1 0 DASH complex subunit Spc34 XRN_M PF17846.1 PSC67907.1 - 0.083 11.8 0.5 0.087 11.8 0.5 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Spc7 PF08317.11 PSC67907.1 - 0.14 11.0 3.7 0.17 10.7 3.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 PSC67907.1 - 0.16 11.0 2.3 0.17 10.9 2.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 TipAS PF07739.13 PSC67907.1 - 1.2 9.7 7.9 19 5.8 7.4 2.5 1 1 0 1 1 1 0 TipAS antibiotic-recognition domain ATP-grasp_2 PF08442.10 PSC67908.1 - 2.3e-62 210.1 1.2 3.3e-62 209.6 1.2 1.2 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 PSC67908.1 - 1.8e-26 92.8 1.5 4.1e-26 91.6 1.5 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 PSC67908.1 - 5.6e-05 22.7 0.3 0.00012 21.6 0.3 1.5 1 0 0 1 1 1 1 ATP-grasp domain HHH_5 PF14520.6 PSC67908.1 - 0.68 10.6 0.0 0.68 10.6 0.0 2.6 3 0 0 3 3 3 0 Helix-hairpin-helix domain LRR_8 PF13855.6 PSC67909.1 - 1.5e-10 40.7 4.5 3e-07 30.1 0.3 4.8 4 1 1 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 PSC67909.1 - 1.9e-08 34.4 4.7 9.5e-05 22.7 0.3 4.5 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PSC67909.1 - 2.6e-05 23.9 5.1 5.3 7.4 0.1 5.9 6 0 0 6 6 6 2 Leucine Rich repeat LRR_1 PF00560.33 PSC67909.1 - 0.0061 16.9 3.7 19 6.3 0.0 5.4 4 0 0 4 4 4 1 Leucine Rich Repeat LRR_9 PF14580.6 PSC67909.1 - 0.041 13.4 0.0 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat rve PF00665.26 PSC67910.1 - 2.4e-19 69.7 0.0 5.2e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC67910.1 - 0.0032 17.2 0.1 0.0084 15.9 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain ArfGap PF01412.18 PSC67912.1 - 2.1e-35 121.3 0.0 3.8e-35 120.5 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf CTD_bind PF04818.13 PSC67914.1 - 1.2e-10 42.1 0.0 2.2e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Surp PF01805.20 PSC67914.1 - 0.018 15.0 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Surp module ABC_tran PF00005.27 PSC67915.1 - 7.5e-42 143.1 1.1 9.2e-22 78.0 0.0 3.9 3 0 0 3 3 3 3 ABC transporter AAA_21 PF13304.6 PSC67915.1 - 3.4e-19 69.8 1.3 0.00034 20.5 0.0 4.2 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PSC67915.1 - 5.3e-12 45.6 0.0 9.4e-05 21.9 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain ABC_tran_Xtn PF12848.7 PSC67915.1 - 3.6e-08 33.3 8.0 1.1e-07 31.7 8.0 1.9 1 0 0 1 1 1 1 ABC transporter AAA_29 PF13555.6 PSC67915.1 - 1.5e-06 27.9 0.4 0.088 12.6 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 PSC67915.1 - 7.9e-06 25.9 0.9 0.13 12.3 0.0 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PSC67915.1 - 1.1e-05 25.4 0.1 0.086 12.7 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 PSC67915.1 - 8e-05 23.2 6.9 0.026 15.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain AAA_24 PF13479.6 PSC67915.1 - 0.00049 19.9 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 PSC67915.1 - 0.0016 18.7 2.5 0.25 11.6 0.0 3.2 2 2 0 2 2 2 1 AAA domain NACHT PF05729.12 PSC67915.1 - 0.0032 17.4 3.1 0.62 10.0 0.1 3.4 3 1 1 4 4 4 1 NACHT domain AAA PF00004.29 PSC67915.1 - 0.0078 16.6 0.1 4.7 7.6 0.0 3.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 PSC67915.1 - 0.0081 15.7 0.5 0.13 11.8 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 PSC67915.1 - 0.017 15.5 0.2 1.3 9.5 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_25 PF13481.6 PSC67915.1 - 0.024 14.2 5.9 3 7.4 0.1 2.8 2 1 0 2 2 2 0 AAA domain AAA_15 PF13175.6 PSC67915.1 - 0.036 13.8 3.4 2.2 7.9 0.0 2.9 4 0 0 4 4 4 0 AAA ATPase domain AAA_33 PF13671.6 PSC67915.1 - 0.049 13.8 5.7 0.17 12.0 0.0 3.2 3 1 0 3 3 3 0 AAA domain NB-ARC PF00931.22 PSC67915.1 - 0.14 11.3 1.7 9.8 5.3 0.2 2.5 2 0 0 2 2 2 0 NB-ARC domain Roc PF08477.13 PSC67915.1 - 0.14 12.4 0.7 11 6.2 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase ABC_ATPase PF09818.9 PSC67915.1 - 0.17 10.6 4.1 17 4.0 0.0 3.3 3 0 0 3 3 3 0 Predicted ATPase of the ABC class NTPase_1 PF03266.15 PSC67915.1 - 0.23 11.3 1.1 15 5.5 0.1 2.4 2 0 0 2 2 2 0 NTPase Dynamin_N PF00350.23 PSC67915.1 - 0.94 9.5 0.0 0.94 9.5 0.0 2.4 3 0 0 3 3 2 0 Dynamin family Mem_trans PF03547.18 PSC67915.1 - 3.2 6.1 21.6 0.18 10.2 4.6 3.4 2 2 1 3 3 3 0 Membrane transport protein Ycf66_N PF07444.11 PSC67916.1 - 7.1e-26 90.1 2.3 9.8e-26 89.7 2.3 1.2 1 0 0 1 1 1 1 Ycf66 protein N-terminus SUIM_assoc PF16619.5 PSC67916.1 - 1.4e-08 34.6 0.0 0.85 9.7 0.0 2.4 2 1 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 TauD PF02668.16 PSC67917.1 - 3.5e-31 109.0 0.9 7.3e-18 65.3 0.0 2.1 1 1 1 2 2 2 2 Taurine catabolism dioxygenase TauD, TfdA family Cu_bind_like PF02298.17 PSC67917.1 - 0.039 14.0 0.0 0.077 13.0 0.0 1.5 1 0 0 1 1 1 0 Plastocyanin-like domain SoxE PF06525.11 PSC67917.1 - 0.054 13.0 0.0 0.087 12.3 0.0 1.3 1 0 0 1 1 1 0 Sulfocyanin (SoxE) domain CsiD PF08943.10 PSC67917.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 CsiD Pribosyltran PF00156.27 PSC67918.1 - 3.1e-06 26.8 0.1 4.5e-06 26.3 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain DUF1387 PF07139.11 PSC67918.1 - 0.26 11.0 0.0 0.39 10.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF1751 PF08551.10 PSC67919.1 - 2.5e-11 44.0 0.6 5.8e-11 42.8 0.6 1.6 1 0 0 1 1 1 1 Eukaryotic integral membrane protein (DUF1751) FixQ PF05545.11 PSC67919.1 - 0.078 13.0 0.0 0.078 13.0 0.0 2.3 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Rhomboid PF01694.22 PSC67919.1 - 0.25 11.4 6.4 0.55 10.2 6.4 1.5 1 0 0 1 1 1 0 Rhomboid family F-box-like PF12937.7 PSC67920.1 - 0.013 15.4 0.2 0.042 13.7 0.2 1.9 1 0 0 1 1 1 0 F-box-like LRR_4 PF12799.7 PSC67920.1 - 0.013 15.9 0.0 7.6 7.1 0.1 3.8 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) FAD_binding_7 PF03441.14 PSC67921.1 - 9e-78 260.4 2.3 1.2e-77 260.0 2.3 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 PSC67921.1 - 1.8e-48 164.6 0.0 3.6e-48 163.7 0.0 1.5 1 0 0 1 1 1 1 DNA photolyase DUF3331 PF11811.8 PSC67921.1 - 0.059 13.2 1.9 0.13 12.1 1.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3331) MRP-S33 PF08293.11 PSC67922.1 - 1.1e-09 38.4 0.1 1.4e-08 34.9 0.1 2.0 1 1 0 1 1 1 1 Mitochondrial ribosomal subunit S27 TT_ORF2 PF02957.15 PSC67923.1 - 2 9.4 5.4 0.4 11.6 1.5 1.8 2 0 0 2 2 2 0 TT viral ORF2 Aldo_ket_red PF00248.21 PSC67924.1 - 1.2e-55 188.8 0.0 2e-55 188.0 0.0 1.3 1 0 0 1 1 1 1 Aldo/keto reductase family Dev_Cell_Death PF10539.9 PSC67924.1 - 0.0028 17.5 0.0 0.0066 16.3 0.0 1.7 1 0 0 1 1 1 1 Development and cell death domain TRAM_2 PF18693.1 PSC67925.1 - 7.2e-15 54.9 0.0 1e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 TRAM domain Radical_SAM PF04055.21 PSC67925.1 - 1.2e-05 25.8 0.0 5.9e-05 23.5 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily TRAM PF01938.20 PSC67925.1 - 0.0033 17.4 0.0 0.0047 16.9 0.0 1.3 1 0 0 1 1 1 1 TRAM domain PP2C PF00481.21 PSC67926.1 - 3.2e-44 151.5 0.0 4.9e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Pkinase PF00069.25 PSC67926.1 - 2.1e-32 112.6 0.0 3e-32 112.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC67926.1 - 2.6e-26 92.5 0.0 5e-26 91.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PSC67926.1 - 3.8e-05 22.6 0.0 8.1e-05 21.6 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 PSC67926.1 - 0.12 11.7 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family SRAP PF02586.14 PSC67927.1 - 8.6e-65 218.3 0.0 1.9e-64 217.2 0.0 1.6 2 0 0 2 2 2 1 SOS response associated peptidase (SRAP) DAD PF02109.16 PSC67927.1 - 3e-25 88.7 0.4 5.8e-25 87.7 0.4 1.4 1 0 0 1 1 1 1 DAD family SUIM_assoc PF16619.5 PSC67927.1 - 0.058 13.5 5.2 0.13 12.4 5.2 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 JSRP PF15312.6 PSC67927.1 - 6.5 6.7 6.1 1.8 8.5 0.4 3.0 3 0 0 3 3 3 0 Junctional sarcoplasmic reticulum protein MFS_5 PF05631.14 PSC67928.1 - 9.9e-139 462.1 11.9 1.3e-138 461.7 11.9 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 PSC67928.1 - 2.2e-14 53.2 29.9 2.3e-14 53.1 26.1 3.3 1 1 0 1 1 1 1 Major Facilitator Superfamily KDZ PF18758.1 PSC67928.1 - 1.3e-10 41.3 0.8 4.4e-10 39.5 0.1 1.9 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase DUF2269 PF10027.9 PSC67928.1 - 0.031 14.3 0.3 0.031 14.3 0.3 2.7 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) MFS_5 PF05631.14 PSC67929.1 - 1.1e-138 462.0 11.9 1.5e-138 461.6 11.9 1.2 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 PSC67929.1 - 4.4e-14 52.2 26.7 4.4e-14 52.2 26.7 3.6 1 1 1 2 2 2 1 Major Facilitator Superfamily KDZ PF18758.1 PSC67929.1 - 1.5e-10 41.1 0.8 4.8e-10 39.4 0.1 1.9 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase DUF2269 PF10027.9 PSC67929.1 - 0.034 14.2 0.3 0.034 14.2 0.3 2.9 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) MFS_5 PF05631.14 PSC67930.1 - 1e-138 462.1 11.9 1.3e-138 461.7 11.9 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 PSC67930.1 - 1.9e-14 53.4 29.7 3.3e-14 52.6 26.5 3.3 1 1 1 2 2 2 2 Major Facilitator Superfamily KDZ PF18758.1 PSC67930.1 - 1.3e-10 41.3 0.8 4.5e-10 39.5 0.1 1.9 2 0 0 2 2 2 1 Kyakuja-Dileera-Zisupton transposase DUF2269 PF10027.9 PSC67930.1 - 0.031 14.3 0.3 0.031 14.3 0.3 2.8 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) HIT PF01230.23 PSC67931.1 - 4.8e-26 91.4 0.0 8.6e-26 90.5 0.0 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 PSC67931.1 - 2.2e-19 70.0 0.0 4e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding 2OG-FeII_Oxy_3 PF13640.6 PSC67931.1 - 2.9e-07 31.3 0.0 6.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HIT PF01230.23 PSC67932.1 - 4.8e-26 91.4 0.0 8.6e-26 90.6 0.0 1.4 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 PSC67932.1 - 2.2e-19 70.0 0.0 4e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding 2OG-FeII_Oxy_3 PF13640.6 PSC67932.1 - 2.9e-07 31.3 0.0 6.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF1804 PF08822.11 PSC67932.1 - 0.0039 17.2 0.1 0.0089 16.0 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1804) APS_kinase PF01583.20 PSC67933.1 - 1.1e-146 483.5 0.0 5.8e-72 240.8 0.0 2.2 2 0 0 2 2 2 2 Adenylylsulphate kinase AAA_33 PF13671.6 PSC67933.1 - 2.9e-11 43.7 0.0 0.00039 20.6 0.0 2.8 3 0 0 3 3 2 2 AAA domain CbiA PF01656.23 PSC67933.1 - 1.2e-10 41.5 0.0 0.00052 20.1 0.0 2.5 2 1 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 PSC67933.1 - 6.8e-08 32.3 0.0 0.013 15.0 0.0 2.3 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 PSC67933.1 - 1.3e-07 31.4 0.0 0.018 14.6 0.0 2.3 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_16 PF13191.6 PSC67933.1 - 3.3e-07 30.9 0.1 0.028 14.8 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 PSC67933.1 - 5.1e-07 30.3 0.0 0.054 14.0 0.0 2.6 2 0 0 2 2 2 2 AAA domain MeaB PF03308.16 PSC67933.1 - 1.5e-06 27.4 0.0 0.059 12.3 0.0 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 PSC67933.1 - 3.3e-06 27.4 0.3 0.32 11.3 0.0 3.7 3 1 1 4 4 4 2 AAA domain AAA_29 PF13555.6 PSC67933.1 - 3.4e-06 26.7 0.1 0.15 11.9 0.0 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain KTI12 PF08433.10 PSC67933.1 - 3.5e-06 26.7 0.0 0.083 12.3 0.0 2.1 2 0 0 2 2 2 2 Chromatin associated protein KTI12 ABC_tran PF00005.27 PSC67933.1 - 4.4e-06 27.3 0.0 0.18 12.3 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_30 PF13604.6 PSC67933.1 - 1.4e-05 24.9 0.0 0.24 11.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain PRK PF00485.18 PSC67933.1 - 0.0002 21.1 0.0 0.77 9.5 0.0 2.3 2 0 0 2 2 2 2 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.6 PSC67933.1 - 0.00022 21.7 0.1 1.1 9.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Thymidylate_kin PF02223.17 PSC67933.1 - 0.0003 20.5 0.0 0.78 9.4 0.0 2.3 2 0 0 2 2 2 2 Thymidylate kinase RNA_helicase PF00910.22 PSC67933.1 - 0.00041 20.7 0.1 1.8 9.0 0.0 2.6 2 0 0 2 2 2 2 RNA helicase SWI2_SNF2 PF18766.1 PSC67933.1 - 0.0011 18.7 0.0 1.5 8.5 0.0 2.1 2 0 0 2 2 2 2 SWI2/SNF2 ATPase NACHT PF05729.12 PSC67933.1 - 0.0018 18.3 0.3 2.3 8.1 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_25 PF13481.6 PSC67933.1 - 0.004 16.8 0.3 4.1 6.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 PSC67933.1 - 0.0058 15.9 0.0 4.1 6.6 0.0 2.5 2 0 0 2 2 2 1 Zeta toxin DinB PF05163.12 PSC67933.1 - 0.011 15.7 0.0 6 6.8 0.0 2.3 2 0 0 2 2 2 0 DinB family IstB_IS21 PF01695.17 PSC67933.1 - 0.011 15.4 0.0 5.8 6.6 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein ArsA_ATPase PF02374.15 PSC67933.1 - 0.011 14.9 0.0 4.5 6.4 0.0 2.2 2 0 0 2 2 2 0 Anion-transporting ATPase G-alpha PF00503.20 PSC67933.1 - 0.012 14.8 0.0 3.1 6.9 0.0 2.1 2 0 0 2 2 2 0 G-protein alpha subunit AAA_5 PF07728.14 PSC67933.1 - 0.018 15.0 0.0 10 6.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 PSC67933.1 - 0.02 14.8 0.0 8.7 6.2 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase Torsin PF06309.11 PSC67933.1 - 0.022 14.8 0.0 8.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Torsin MipZ PF09140.11 PSC67933.1 - 0.023 14.0 0.2 7 5.9 0.0 2.2 2 0 0 2 2 2 0 ATPase MipZ Yeast-kill-tox PF09207.11 PSC67933.1 - 0.027 15.1 0.7 3.1 8.5 0.2 2.6 2 0 0 2 2 2 0 Yeast killer toxin NB-ARC PF00931.22 PSC67933.1 - 0.028 13.6 0.1 3 7.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain T2SSE PF00437.20 PSC67933.1 - 0.039 13.0 0.0 9.1 5.3 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein TIP49 PF06068.13 PSC67933.1 - 0.045 12.9 0.0 7.2 5.7 0.0 2.1 2 0 0 2 2 2 0 TIP49 P-loop domain Mur_ligase_M PF08245.12 PSC67933.1 - 0.046 13.7 0.0 14 5.6 0.0 2.5 2 0 0 2 2 2 0 Mur ligase middle domain AAA_24 PF13479.6 PSC67933.1 - 0.05 13.3 0.0 12 5.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 PSC67933.1 - 0.074 12.9 0.0 16 5.4 0.0 2.3 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B CLP1_P PF16575.5 PSC67933.1 - 0.077 12.8 0.0 27 4.5 0.0 3.0 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop cobW PF02492.19 PSC67933.1 - 0.094 12.3 0.0 16 5.0 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NTPase_1 PF03266.15 PSC67933.1 - 0.11 12.4 0.0 21 5.0 0.0 2.5 2 0 0 2 2 2 0 NTPase ATP_bind_1 PF03029.17 PSC67933.1 - 0.13 12.1 0.3 19 5.0 0.0 2.3 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein Mg_chelatase PF01078.21 PSC67933.1 - 0.13 11.6 0.1 19 4.6 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI CTP_transf_like PF01467.26 PSC67933.1 - 0.15 12.3 0.0 23 5.2 0.0 2.2 2 0 0 2 2 2 0 Cytidylyltransferase-like Fer4_NifH PF00142.18 PSC67933.1 - 0.15 11.5 0.0 24 4.2 0.0 2.5 2 0 0 2 2 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family TPT PF03151.16 PSC67934.1 - 2e-97 326.1 19.1 2.3e-97 325.8 19.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PSC67934.1 - 7.7e-09 35.8 28.0 4.2e-06 27.0 12.9 2.4 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 PSC67934.1 - 0.00055 19.2 14.6 0.0031 16.8 14.6 1.9 1 1 0 1 1 1 1 UAA transporter family DnaJ PF00226.31 PSC67935.1 - 1.5e-18 66.7 0.3 1.5e-18 66.7 0.3 2.6 2 1 0 2 2 2 1 DnaJ domain Myb_DNA-binding PF00249.31 PSC67935.1 - 1.4e-10 41.2 8.6 8e-06 26.0 0.2 3.0 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC67935.1 - 3.3e-06 27.3 4.0 0.0019 18.4 0.1 3.4 4 0 0 4 4 4 2 Myb-like DNA-binding domain VID27 PF08553.10 PSC67936.1 - 3.9e-49 167.6 0.0 6.4e-49 166.9 0.0 1.3 1 0 0 1 1 1 1 VID27 C-terminal WD40-like domain WD40 PF00400.32 PSC67936.1 - 0.012 16.4 0.0 2.2 9.3 0.0 3.6 3 0 0 3 3 3 0 WD domain, G-beta repeat SRCR PF00530.18 PSC67937.1 - 3.9e-69 229.5 28.1 2.9e-11 43.8 0.0 9.6 9 0 0 9 9 9 9 Scavenger receptor cysteine-rich domain PIN_4 PF13638.6 PSC67937.1 - 2.9e-17 63.2 0.0 4.3e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 PIN domain F-box-like PF12937.7 PSC67937.1 - 3.3e-07 30.1 0.1 3e-06 27.0 0.0 2.6 2 0 0 2 2 2 1 F-box-like PA14 PF07691.12 PSC67937.1 - 7.5e-07 29.1 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 PA14 domain Hepsin-SRCR PF09272.10 PSC67937.1 - 0.0018 18.8 0.2 19 5.8 0.0 5.1 5 0 0 5 5 5 1 Hepsin, SRCR domain SRCR_2 PF15494.6 PSC67937.1 - 0.39 11.3 5.4 47 4.6 0.0 5.5 6 0 0 6 6 6 0 Scavenger receptor cysteine-rich domain SRCR PF00530.18 PSC67938.1 - 1.5e-70 234.0 27.4 2.8e-11 43.8 0.0 9.6 9 1 0 9 9 9 9 Scavenger receptor cysteine-rich domain PIN_4 PF13638.6 PSC67938.1 - 2.9e-17 63.2 0.0 4.3e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 PIN domain F-box-like PF12937.7 PSC67938.1 - 3.2e-07 30.1 0.1 3e-06 27.0 0.0 2.6 2 0 0 2 2 2 1 F-box-like PA14 PF07691.12 PSC67938.1 - 4e-06 26.7 0.0 6.4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 PA14 domain Hepsin-SRCR PF09272.10 PSC67938.1 - 0.0018 18.8 0.2 19 5.8 0.0 5.1 5 0 0 5 5 5 1 Hepsin, SRCR domain SRCR_2 PF15494.6 PSC67938.1 - 0.55 10.8 5.9 47 4.6 0.0 5.5 6 0 0 6 6 6 0 Scavenger receptor cysteine-rich domain SRCR PF00530.18 PSC67939.1 - 1.5e-70 234.0 27.2 2.9e-11 43.8 0.0 9.6 9 1 0 9 9 9 9 Scavenger receptor cysteine-rich domain PIN_4 PF13638.6 PSC67939.1 - 2.9e-17 63.2 0.0 4.3e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 PIN domain F-box-like PF12937.7 PSC67939.1 - 3.3e-07 30.1 0.1 3e-06 27.0 0.0 2.6 2 0 0 2 2 2 1 F-box-like PA14 PF07691.12 PSC67939.1 - 7.5e-07 29.1 0.0 1.2e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 PA14 domain Hepsin-SRCR PF09272.10 PSC67939.1 - 0.0019 18.7 0.2 19 5.8 0.0 5.1 5 0 0 5 5 5 1 Hepsin, SRCR domain SRCR_2 PF15494.6 PSC67939.1 - 0.58 10.7 5.9 47 4.6 0.0 5.5 6 0 0 6 6 6 0 Scavenger receptor cysteine-rich domain IMS PF00817.20 PSC67940.1 - 3.7e-33 114.6 0.0 6.1e-33 113.9 0.0 1.4 1 0 0 1 1 1 1 impB/mucB/samB family IMS_C PF11799.8 PSC67940.1 - 6.2e-13 49.5 0.0 2.7e-12 47.4 0.0 1.9 2 0 0 2 2 2 1 impB/mucB/samB family C-terminal domain UBM PF14377.6 PSC67940.1 - 0.00012 21.4 0.6 0.00012 21.4 0.6 2.8 2 0 0 2 2 2 1 Ubiquitin binding region IMS_HHH PF11798.8 PSC67940.1 - 0.0053 17.0 0.1 0.012 15.8 0.1 1.7 1 0 0 1 1 1 1 IMS family HHH motif zf-CCHC_6 PF15288.6 PSC67940.1 - 0.18 11.7 0.8 0.67 9.8 0.1 2.3 2 0 0 2 2 2 0 Zinc knuckle DEAD PF00270.29 PSC67942.1 - 1e-34 119.8 0.6 3.8e-34 118.0 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC67942.1 - 6e-26 91.0 0.5 1.8e-25 89.4 0.1 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 PSC67942.1 - 0.078 13.2 0.6 0.32 11.3 0.6 2.1 1 1 0 1 1 1 0 AAA domain DEAD PF00270.29 PSC67943.1 - 1e-34 119.8 0.6 3.8e-34 118.0 0.1 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC67943.1 - 6e-26 91.0 0.5 1.8e-25 89.4 0.1 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 PSC67943.1 - 0.078 13.2 0.6 0.32 11.3 0.6 2.1 1 1 0 1 1 1 0 AAA domain Aminotran_5 PF00266.19 PSC67944.1 - 5.9e-52 176.9 0.0 6.8e-52 176.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V DUF1043 PF06295.12 PSC67945.1 - 0.011 15.7 2.3 0.023 14.7 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF3322 PF11795.8 PSC67945.1 - 0.025 14.6 3.8 3 7.8 0.6 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Mer2 PF09074.10 PSC67945.1 - 0.058 13.2 0.8 0.13 12.1 0.8 1.5 1 0 0 1 1 1 0 Mer2 Apolipoprotein PF01442.18 PSC67945.1 - 0.075 12.9 6.6 0.14 12.0 6.6 1.3 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain IFT57 PF10498.9 PSC67945.1 - 0.12 11.3 2.3 0.27 10.1 1.2 1.9 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Arfaptin PF06456.13 PSC67945.1 - 0.13 11.8 2.0 0.22 11.1 2.0 1.3 1 0 0 1 1 1 0 Arfaptin-like domain Phage_GPO PF05929.11 PSC67945.1 - 0.16 11.6 3.5 0.24 11.0 3.5 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase RHD3 PF05879.12 PSC67945.1 - 0.23 9.5 1.7 0.32 9.1 1.7 1.1 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) DUF3584 PF12128.8 PSC67945.1 - 0.31 8.5 4.7 0.43 8.0 4.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Seryl_tRNA_N PF02403.22 PSC67945.1 - 0.33 11.2 4.8 0.78 10.0 4.8 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain NUDIX PF00293.28 PSC67946.1 - 3.4e-10 40.1 0.1 7.9e-10 38.9 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain ADIP PF11559.8 PSC67946.1 - 0.00032 20.8 3.4 0.00054 20.1 3.4 1.2 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding MAD PF05557.13 PSC67946.1 - 0.0017 16.8 0.6 0.0023 16.4 0.6 1.0 1 0 0 1 1 1 1 Mitotic checkpoint protein bZIP_1 PF00170.21 PSC67946.1 - 0.0051 16.9 1.0 0.012 15.6 0.1 2.1 2 0 0 2 2 2 1 bZIP transcription factor DivIC PF04977.15 PSC67946.1 - 0.03 14.1 1.6 0.058 13.2 0.9 1.9 1 1 0 1 1 1 0 Septum formation initiator ZapB PF06005.12 PSC67946.1 - 0.056 13.9 4.0 0.12 12.8 4.0 1.5 1 0 0 1 1 1 0 Cell division protein ZapB Spc7 PF08317.11 PSC67946.1 - 0.065 12.1 1.6 0.096 11.6 1.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein KLRAQ PF10205.9 PSC67946.1 - 0.08 13.2 1.1 0.14 12.4 1.1 1.3 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein TACC_C PF05010.14 PSC67946.1 - 0.081 12.7 0.5 0.13 12.0 0.5 1.2 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Fez1 PF06818.15 PSC67946.1 - 0.086 13.3 0.8 0.14 12.6 0.8 1.2 1 0 0 1 1 1 0 Fez1 SKA1 PF07160.12 PSC67946.1 - 0.13 12.1 0.2 0.19 11.5 0.2 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 UPF0242 PF06785.11 PSC67946.1 - 0.14 12.2 0.5 0.22 11.6 0.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF16 PF01519.16 PSC67946.1 - 0.16 12.5 0.4 0.26 11.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 DUF4201 PF13870.6 PSC67946.1 - 0.22 11.2 1.2 0.44 10.2 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) TMF_TATA_bd PF12325.8 PSC67946.1 - 0.51 10.6 3.1 0.92 9.7 3.1 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding CENP-H PF05837.12 PSC67946.1 - 0.7 10.3 4.0 1.3 9.5 4.0 1.4 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Csm1_N PF18504.1 PSC67946.1 - 2 8.8 4.5 11 6.4 1.3 2.3 2 0 0 2 2 2 0 Csm1 N-terminal domain TMF_DNA_bd PF12329.8 PSC67946.1 - 2.3 8.3 5.0 1.2 9.1 1.3 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding Pkinase PF00069.25 PSC67947.1 - 2.8e-52 177.7 0.0 4.4e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC67947.1 - 1.9e-26 92.9 0.0 3e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kelch_3 PF13415.6 PSC67947.1 - 2.2e-26 91.6 14.9 5.1e-07 29.8 0.1 8.1 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_5 PF13854.6 PSC67947.1 - 3.3e-21 74.8 7.5 3.2e-05 23.8 0.1 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 PSC67947.1 - 2.9e-20 71.6 5.6 1.6e-06 27.6 0.0 6.4 6 1 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 PSC67947.1 - 6.8e-20 70.6 8.0 4.4e-05 23.6 0.0 6.9 5 2 2 7 7 7 4 Kelch motif ACBP PF00887.19 PSC67947.1 - 3.3e-19 68.9 0.0 6.4e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Kelch_4 PF13418.6 PSC67947.1 - 4.8e-19 68.1 13.0 9e-06 25.6 0.0 6.6 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 PSC67947.1 - 1.2e-16 59.9 3.8 5.3e-05 23.0 0.0 5.8 6 1 0 6 6 6 4 Kelch motif Golgin_A5 PF09787.9 PSC67947.1 - 0.11 12.0 6.3 0.17 11.3 6.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 CAP_N PF01213.19 PSC67947.1 - 0.69 9.3 15.4 1.3 8.4 7.1 2.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal AAA_13 PF13166.6 PSC67947.1 - 2.3 6.8 7.6 3.2 6.3 7.6 1.1 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 PSC67948.1 - 2.8e-52 177.7 0.0 4.4e-52 177.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kelch_3 PF13415.6 PSC67948.1 - 1.6e-26 92.0 14.9 5.1e-07 29.8 0.1 8.1 8 0 0 8 8 8 4 Galactose oxidase, central domain Pkinase_Tyr PF07714.17 PSC67948.1 - 1.9e-26 92.9 0.0 2.9e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kelch_5 PF13854.6 PSC67948.1 - 3.2e-21 74.9 7.5 3.2e-05 23.8 0.1 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 PSC67948.1 - 2.9e-20 71.6 5.6 1.6e-06 27.6 0.0 6.4 6 1 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 PSC67948.1 - 6.8e-20 70.6 8.0 4.4e-05 23.6 0.0 6.9 5 2 2 7 7 7 4 Kelch motif ACBP PF00887.19 PSC67948.1 - 3.3e-19 68.9 0.0 6.4e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Acyl CoA binding protein Kelch_4 PF13418.6 PSC67948.1 - 7.1e-19 67.6 13.5 9e-06 25.6 0.0 6.6 6 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_2 PF07646.15 PSC67948.1 - 1.2e-16 59.9 4.3 3.8e-05 23.5 0.0 5.8 6 1 0 6 6 6 4 Kelch motif Golgin_A5 PF09787.9 PSC67948.1 - 0.11 12.0 6.3 0.17 11.3 6.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 CAP_N PF01213.19 PSC67948.1 - 0.69 9.3 15.4 1.3 8.4 7.1 2.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal AAA_13 PF13166.6 PSC67948.1 - 2.2 6.8 7.6 3.2 6.3 7.6 1.1 1 0 0 1 1 1 0 AAA domain WD40_3 PF15911.5 PSC67950.1 - 5.3e-11 42.4 0.0 1.2e-10 41.3 0.0 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC67950.1 - 0.0047 17.2 0.0 0.22 11.8 0.0 2.7 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 PSC67950.1 - 0.034 13.2 1.3 0.071 12.1 1.3 1.4 1 0 0 1 1 1 0 Coatomer WD associated region Clathrin PF00637.20 PSC67950.1 - 0.18 11.6 0.0 63 3.4 0.0 3.6 3 1 2 5 5 5 0 Region in Clathrin and VPS Kazal_3 PF18434.1 PSC67950.1 - 8.1 6.3 8.1 14 5.5 1.8 2.8 2 0 0 2 2 2 0 Kazal-type serine protease inhibitor domain AhpC-TSA PF00578.21 PSC67951.1 - 9.3e-44 148.3 0.0 5.5e-38 129.7 0.0 2.2 2 0 0 2 2 2 2 AhpC/TSA family Redoxin PF08534.10 PSC67951.1 - 2.1e-19 69.7 0.0 2.4e-15 56.5 0.0 2.2 2 0 0 2 2 2 2 Redoxin Thioredoxin PF00085.20 PSC67951.1 - 4.1e-17 62.1 0.1 6.8e-17 61.3 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin 1-cysPrx_C PF10417.9 PSC67951.1 - 1.7e-12 47.0 0.1 4.1e-12 45.7 0.1 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Thioredoxin_8 PF13905.6 PSC67951.1 - 0.00024 21.4 0.0 0.0014 18.9 0.0 2.1 2 1 0 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 PSC67951.1 - 0.0018 18.7 1.3 0.0043 17.5 0.1 2.2 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_9 PF14595.6 PSC67951.1 - 0.089 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Fasciclin PF02469.22 PSC67952.1 - 1.4e-19 70.6 0.3 2.1e-18 66.8 0.3 2.3 1 1 0 1 1 1 1 Fasciclin domain DUF3223 PF11523.8 PSC67952.1 - 0.17 12.7 0.0 1 10.3 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3223) Fe-ADH PF00465.19 PSC67953.1 - 1.7e-76 257.4 6.6 5.6e-52 176.7 3.1 3.1 2 1 1 3 3 3 3 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 PSC67953.1 - 1e-06 28.6 3.0 0.013 15.2 1.3 2.6 2 1 0 2 2 2 2 Iron-containing alcohol dehydrogenase PAP_fibrillin PF04755.12 PSC67954.1 - 8.4e-06 25.9 0.0 0.00062 19.8 0.0 2.5 1 1 1 2 2 2 2 PAP_fibrillin Paramyxo_ncap PF00973.19 PSC67954.1 - 5.1 5.9 8.1 7.5 5.3 8.1 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Trypsin PF00089.26 PSC67955.1 - 2.1e-12 47.3 0.0 2.4e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Trypsin DUF1771 PF08590.10 PSC67956.1 - 3.3e-12 46.6 19.7 3.3e-12 46.6 19.7 3.4 4 0 0 4 4 4 1 Domain of unknown function (DUF1771) Smr PF01713.21 PSC67956.1 - 9.2e-08 32.3 2.4 1.9e-07 31.3 0.8 2.4 2 0 0 2 2 2 1 Smr domain Peptidase_C69 PF03577.15 PSC67957.1 - 1.7e-83 280.8 0.0 2.5e-83 280.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family C69 FAD_binding_4 PF01565.23 PSC67957.1 - 4.4e-13 49.2 0.3 1.2e-11 44.5 0.0 3.5 4 0 0 4 4 4 1 FAD binding domain AAT PF03417.16 PSC67957.1 - 0.17 11.5 0.0 0.32 10.6 0.0 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Cpn60_TCP1 PF00118.24 PSC67958.1 - 5e-155 516.9 1.3 6e-155 516.6 1.3 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RNA_pol_Rpc34 PF05158.12 PSC67959.1 - 1.8e-67 228.1 0.2 4.1e-47 161.2 0.0 2.7 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit RPA_C PF08784.11 PSC67959.1 - 0.00044 20.9 0.1 0.22 12.2 0.0 3.1 3 0 0 3 3 3 1 Replication protein A C terminal MarR PF01047.22 PSC67959.1 - 0.004 17.0 0.2 0.043 13.7 0.1 2.7 4 0 0 4 4 4 1 MarR family B-block_TFIIIC PF04182.12 PSC67959.1 - 0.005 17.0 0.1 0.011 15.8 0.1 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC TrmB PF01978.19 PSC67959.1 - 0.0054 16.6 0.1 0.075 12.9 0.1 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB FAM180 PF15173.6 PSC67959.1 - 0.028 14.4 0.2 0.093 12.7 0.0 1.9 2 1 0 2 2 2 0 FAM180 family HTH_24 PF13412.6 PSC67959.1 - 0.031 13.8 0.4 23 4.7 0.0 3.5 4 0 0 4 4 4 0 Winged helix-turn-helix DNA-binding HTH_37 PF13744.6 PSC67959.1 - 0.04 13.9 0.4 0.13 12.2 0.1 1.9 2 0 0 2 2 2 0 Helix-turn-helix domain TFIIE_alpha PF02002.17 PSC67959.1 - 0.041 13.8 0.5 0.085 12.7 0.1 1.7 2 0 0 2 2 2 0 TFIIE alpha subunit MarR_2 PF12802.7 PSC67959.1 - 0.12 12.3 0.3 3.2 7.7 0.1 2.7 3 1 0 3 3 3 0 MarR family rve PF00665.26 PSC67960.1 - 8.5e-19 67.9 0.0 1.8e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Ku PF02735.16 PSC67960.1 - 3.3e-05 23.7 0.0 6e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain rve_3 PF13683.6 PSC67960.1 - 0.0075 16.0 0.0 0.019 14.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Cupin_1 PF00190.22 PSC67961.1 - 2.1e-29 102.1 0.0 3.7e-14 52.6 0.0 2.3 2 0 0 2 2 2 2 Cupin Cupin_2 PF07883.11 PSC67961.1 - 7.9e-16 57.5 0.0 1.4e-07 31.1 0.0 2.4 2 0 0 2 2 2 2 Cupin domain Response_reg PF00072.24 PSC67961.1 - 5.9e-13 49.0 0.0 1.3e-12 47.9 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Cupin_3 PF05899.12 PSC67961.1 - 2.6e-05 23.8 0.0 0.14 11.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF861) Ppnp PF06865.11 PSC67961.1 - 0.053 13.9 0.0 3.6 8.1 0.0 2.3 2 0 0 2 2 2 0 Pyrimidine/purine nucleoside phosphorylase WD40 PF00400.32 PSC67962.1 - 6.5e-39 131.2 25.1 0.00013 22.7 0.0 9.1 9 0 0 9 9 9 7 WD domain, G-beta repeat Fasciclin PF02469.22 PSC67962.1 - 2.3e-26 92.5 4.9 1.1e-16 61.2 0.2 4.2 3 1 0 3 3 3 3 Fasciclin domain U-box PF04564.15 PSC67962.1 - 4.3e-20 71.7 0.0 8.4e-20 70.7 0.0 1.4 1 0 0 1 1 1 1 U-box domain PQQ_3 PF13570.6 PSC67962.1 - 1.4e-09 38.1 18.2 0.013 16.0 0.1 8.2 9 0 0 9 9 9 3 PQQ-like domain Nup160 PF11715.8 PSC67962.1 - 1.5e-07 30.5 18.5 0.068 11.8 0.2 6.3 3 3 4 7 7 7 4 Nucleoporin Nup120/160 BBS2_Mid PF14783.6 PSC67962.1 - 0.0018 18.3 0.1 1 9.5 0.0 4.2 4 1 1 6 6 6 1 Ciliary BBSome complex subunit 2, middle region zf-Nse PF11789.8 PSC67962.1 - 0.0022 17.8 0.0 0.0043 16.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit His_Phos_2 PF00328.22 PSC67963.1 - 9.2e-22 77.9 0.0 3.3e-20 72.8 0.0 2.8 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Serglycin PF04360.12 PSC67963.1 - 0.69 9.9 3.3 1.5 8.8 3.3 1.5 1 0 0 1 1 1 0 Serglycin SET PF00856.28 PSC67964.1 - 5.6e-09 36.6 0.0 1.1e-08 35.7 0.0 1.6 1 1 0 1 1 1 1 SET domain MCM PF00493.23 PSC67965.1 - 7.3e-100 332.7 0.0 1.1e-99 332.1 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PSC67965.1 - 1.4e-38 131.6 0.1 2.9e-38 130.6 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PSC67965.1 - 1.7e-28 98.9 0.3 4.1e-28 97.6 0.3 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 PSC67965.1 - 1.7e-13 51.1 0.0 4.4e-13 49.7 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 PSC67965.1 - 3.6e-07 30.3 0.0 2e-06 27.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 PSC67965.1 - 5.3e-07 29.2 0.2 0.00015 21.3 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA PF00004.29 PSC67965.1 - 0.00074 20.0 0.0 0.098 13.1 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_3 PF07726.11 PSC67965.1 - 0.0011 18.8 0.0 0.0065 16.3 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 PSC67965.1 - 0.016 14.9 0.1 3.5 7.3 0.0 2.7 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_16 PF13191.6 PSC67965.1 - 0.29 11.5 2.6 0.59 10.5 0.1 2.6 2 2 1 3 3 3 0 AAA ATPase domain RVT_3 PF13456.6 PSC67966.1 - 2.4e-25 88.7 0.1 5.3e-25 87.6 0.1 1.6 1 0 0 1 1 1 1 Reverse transcriptase-like Cauli_VI PF01693.16 PSC67966.1 - 2e-16 60.0 0.9 4.3e-16 58.9 0.9 1.6 1 0 0 1 1 1 1 Caulimovirus viroplasmin RNase_H PF00075.24 PSC67966.1 - 3.4e-07 30.5 0.0 1.3e-06 28.6 0.0 2.0 1 1 0 1 1 1 1 RNase H DUF2967 PF11179.8 PSC67966.1 - 6.5 4.7 21.1 0.061 11.4 2.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2967) DUF1286 PF06939.11 PSC67967.1 - 0.042 14.1 0.1 0.047 14.0 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1286) FMO-like PF00743.19 PSC67968.1 - 5.8e-59 199.9 0.0 1.7e-38 132.4 0.0 2.9 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 PSC67968.1 - 8.1e-19 68.0 0.0 2.4e-12 46.7 0.0 3.3 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PSC67968.1 - 5e-14 52.2 2.0 5.2e-13 48.9 2.0 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PSC67968.1 - 9e-12 45.1 0.4 9e-12 45.1 0.4 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 PSC67968.1 - 1e-08 34.9 0.4 4e-08 33.0 0.2 1.9 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 PSC67968.1 - 9e-06 26.2 0.9 0.003 18.1 0.4 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PSC67968.1 - 0.00019 21.0 0.2 0.00037 20.0 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 PSC67968.1 - 0.0002 21.1 11.1 0.0011 18.6 2.6 2.9 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 PSC67968.1 - 0.00025 20.3 0.5 0.023 13.8 0.0 2.6 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_2 PF00890.24 PSC67968.1 - 0.00025 20.2 2.7 0.00025 20.2 2.7 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 PSC67968.1 - 0.00031 19.6 1.4 0.00053 18.8 1.4 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 PSC67968.1 - 0.00043 19.6 1.5 0.00043 19.6 1.5 2.1 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 PSC67968.1 - 0.014 15.4 0.0 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 PSC67968.1 - 0.016 14.6 0.4 4.9 6.4 0.3 2.2 2 0 0 2 2 2 0 ThiF family AlaDh_PNT_C PF01262.21 PSC67968.1 - 0.02 14.2 0.9 0.038 13.3 0.9 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 PSC67968.1 - 0.025 13.8 0.4 0.025 13.8 0.4 2.6 3 0 0 3 3 3 0 Thi4 family NAD_binding_9 PF13454.6 PSC67968.1 - 0.094 12.7 4.2 2.5 8.1 0.1 3.4 3 1 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.22 PSC67968.1 - 0.1 11.6 1.8 0.18 10.8 1.8 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 PSC67968.1 - 0.11 11.5 0.2 0.19 10.8 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Peptidase_M17_N PF02789.17 PSC67968.1 - 0.13 12.2 0.5 0.65 9.9 0.2 2.2 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain ApbA PF02558.16 PSC67968.1 - 0.3 10.7 1.7 3.3 7.3 0.9 2.8 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA FMO-like PF00743.19 PSC67969.1 - 1.1e-51 175.9 0.0 3.6e-19 68.6 0.0 3.1 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 PSC67969.1 - 4e-18 65.7 0.0 2.3e-12 46.8 0.0 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PSC67969.1 - 7e-14 51.7 2.4 1.1e-12 47.8 2.4 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PSC67969.1 - 8.4e-12 45.2 0.4 8.4e-12 45.2 0.4 2.3 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 PSC67969.1 - 1.7e-08 34.2 0.1 3.3e-08 33.3 0.1 1.5 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 PSC67969.1 - 1e-05 26.0 0.6 0.0029 18.1 0.4 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PSC67969.1 - 0.00024 20.3 2.7 0.00024 20.3 2.7 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 PSC67969.1 - 0.0003 19.6 1.4 0.0005 18.9 1.4 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.7 PSC67969.1 - 0.00031 20.2 0.9 0.00062 19.2 0.9 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 PSC67969.1 - 0.00035 20.3 11.6 0.0011 18.7 2.6 2.7 3 0 0 3 3 3 2 FAD dependent oxidoreductase K_oxygenase PF13434.6 PSC67969.1 - 0.00036 19.8 0.7 0.022 13.9 0.0 2.3 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_binding_3 PF01494.19 PSC67969.1 - 0.0004 19.7 1.5 0.0004 19.7 1.5 2.1 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 PSC67969.1 - 0.013 15.6 0.0 0.17 11.9 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 PSC67969.1 - 0.014 14.7 0.4 4.6 6.5 0.3 2.2 2 0 0 2 2 2 0 ThiF family AlaDh_PNT_C PF01262.21 PSC67969.1 - 0.016 14.5 0.7 0.031 13.6 0.7 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 PSC67969.1 - 0.023 13.9 0.4 0.023 13.9 0.4 2.6 3 0 0 3 3 3 0 Thi4 family NAD_binding_9 PF13454.6 PSC67969.1 - 0.077 13.0 3.3 2.8 7.9 0.3 3.1 3 0 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.22 PSC67969.1 - 0.098 11.7 1.8 0.17 10.9 1.8 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 PSC67969.1 - 0.1 11.6 0.2 0.18 10.9 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Peptidase_M17_N PF02789.17 PSC67969.1 - 0.12 12.2 0.5 0.61 9.9 0.2 2.2 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain ApbA PF02558.16 PSC67969.1 - 0.26 10.9 1.7 3.1 7.4 0.9 2.8 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA FMO-like PF00743.19 PSC67970.1 - 1.7e-59 201.7 0.0 5e-39 134.1 0.0 2.9 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 PSC67970.1 - 3.3e-20 72.6 0.0 2.4e-12 46.7 0.0 3.5 3 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PSC67970.1 - 6.1e-14 51.9 2.2 8.2e-13 48.2 2.2 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PSC67970.1 - 9e-12 45.1 0.4 9e-12 45.1 0.4 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 PSC67970.1 - 9.3e-09 35.1 0.4 4.2e-08 32.9 0.3 2.0 1 1 1 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 PSC67970.1 - 9.1e-06 26.2 0.9 0.003 18.1 0.4 2.7 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PSC67970.1 - 5.8e-05 22.4 0.3 0.024 13.8 0.0 3.1 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) FAD_oxidored PF12831.7 PSC67970.1 - 0.0002 20.9 0.2 0.00039 19.9 0.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PSC67970.1 - 0.00025 20.2 2.7 0.00025 20.2 2.7 1.9 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 PSC67970.1 - 0.00028 20.6 11.6 0.00083 19.0 2.2 2.8 3 1 0 3 3 3 2 FAD dependent oxidoreductase HI0933_like PF03486.14 PSC67970.1 - 0.00031 19.6 1.4 0.00053 18.8 1.4 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 PSC67970.1 - 0.00043 19.6 1.5 0.00043 19.6 1.5 2.1 2 0 0 2 2 2 1 FAD binding domain Shikimate_DH PF01488.20 PSC67970.1 - 0.014 15.4 0.0 0.18 11.8 0.0 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 PSC67970.1 - 0.016 14.6 0.4 4.9 6.4 0.3 2.3 2 0 0 2 2 2 0 ThiF family AlaDh_PNT_C PF01262.21 PSC67970.1 - 0.02 14.2 0.9 0.038 13.3 0.9 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 PSC67970.1 - 0.025 13.8 0.4 0.025 13.8 0.4 2.6 3 0 0 3 3 3 0 Thi4 family NAD_binding_9 PF13454.6 PSC67970.1 - 0.028 14.4 7.0 0.24 11.4 0.9 3.6 2 1 0 3 3 3 0 FAD-NAD(P)-binding GIDA PF01134.22 PSC67970.1 - 0.11 11.6 1.8 0.18 10.8 1.8 1.4 1 0 0 1 1 1 0 Glucose inhibited division protein A Lycopene_cycl PF05834.12 PSC67970.1 - 0.11 11.5 0.2 0.19 10.8 0.2 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Peptidase_M17_N PF02789.17 PSC67970.1 - 0.13 12.1 0.5 0.65 9.9 0.2 2.2 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain ApbA PF02558.16 PSC67970.1 - 0.3 10.7 1.7 3.3 7.3 0.9 2.8 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Lycopene_cycl PF05834.12 PSC67972.1 - 4.5e-111 371.6 0.0 5.5e-111 371.3 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein DAO PF01266.24 PSC67972.1 - 2.2e-06 27.5 0.4 0.073 12.6 0.0 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PSC67972.1 - 3.7e-05 23.1 0.0 0.0034 16.6 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PSC67972.1 - 7.3e-05 22.8 0.1 0.058 13.4 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 PSC67972.1 - 0.00021 21.4 0.0 0.00072 19.7 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 PSC67972.1 - 0.00041 19.7 0.0 0.011 15.0 0.0 2.2 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 PSC67972.1 - 0.0014 17.6 1.5 0.0057 15.6 0.1 2.1 1 1 1 2 2 2 1 Tryptophan halogenase FAD_binding_2 PF00890.24 PSC67972.1 - 0.0015 17.7 0.0 0.0031 16.6 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 PSC67972.1 - 0.0028 17.1 0.8 0.0089 15.4 0.8 1.9 1 1 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 PSC67972.1 - 0.0051 15.6 0.0 0.0086 14.8 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_3 PF01494.19 PSC67972.1 - 0.023 13.9 0.0 0.04 13.2 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain 2-Hacid_dh_C PF02826.19 PSC67972.1 - 0.024 14.0 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XdhC_C PF13478.6 PSC67972.1 - 0.032 14.7 0.0 0.069 13.7 0.0 1.6 1 0 0 1 1 1 0 XdhC Rossmann domain 3HCDH_N PF02737.18 PSC67972.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox_3 PF13738.6 PSC67972.1 - 0.2 10.9 0.0 0.35 10.1 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PriC PF07445.12 PSC67972.1 - 4.2 7.3 7.7 26 4.7 6.0 2.1 2 0 0 2 2 2 0 Primosomal replication protein priC PCI PF01399.27 PSC67973.1 - 4.4e-09 36.8 0.0 9.2e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 PCI domain HTH_25 PF13413.6 PSC67973.1 - 0.039 13.8 0.1 13 5.8 0.0 2.8 2 1 1 3 3 3 0 Helix-turn-helix domain Noc2 PF03715.13 PSC67974.1 - 2.3e-103 345.6 0.1 5.7e-103 344.3 0.0 1.7 2 0 0 2 2 2 1 Noc2p family MSP1_C PF07462.11 PSC67974.1 - 0.73 8.5 3.4 1.5 7.5 3.4 1.4 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus FUSC PF04632.12 PSC67975.1 - 2.8 6.4 5.3 3 6.3 5.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Fer4_8 PF13183.6 PSC67975.1 - 3.5 8.1 9.0 20 5.7 9.0 2.1 1 1 0 1 1 1 0 4Fe-4S dicluster domain Sec62 PF03839.16 PSC67975.1 - 6.1 6.3 10.2 6.7 6.2 10.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 NAM-associated PF14303.6 PSC67975.1 - 7.5 7.2 16.4 9.5 6.9 16.4 1.2 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain rve PF00665.26 PSC67976.1 - 8.4e-19 67.9 0.0 1.8e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC67976.1 - 0.0066 16.2 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Methyltransf_16 PF10294.9 PSC67978.1 - 1.7e-20 73.5 0.0 2.7e-20 72.8 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Acetyltransf_1 PF00583.25 PSC67978.1 - 2.1e-08 34.4 0.0 4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PSC67978.1 - 6.5e-08 32.9 0.0 1.5e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PSC67978.1 - 8.2e-07 29.0 0.0 1.5e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC67978.1 - 0.00014 21.7 0.0 0.00041 20.3 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Methyltransf_25 PF13649.6 PSC67978.1 - 0.00019 22.1 0.1 0.004 17.8 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain PrmA PF06325.13 PSC67978.1 - 0.00024 20.6 0.1 0.00042 19.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 PSC67978.1 - 0.008 16.0 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PSC67978.1 - 0.0086 15.6 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Met_10 PF02475.16 PSC67978.1 - 0.015 15.0 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Cons_hypoth95 PF03602.15 PSC67978.1 - 0.021 14.5 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 PSC67978.1 - 0.023 15.4 0.0 0.13 13.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Acetyltransf_4 PF13420.7 PSC67978.1 - 0.03 14.4 0.0 0.05 13.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 PSC67978.1 - 0.08 12.7 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Methyltransf_11 PF08241.12 PSC67978.1 - 0.16 12.7 0.2 5.9 7.6 0.1 2.6 2 0 0 2 2 2 0 Methyltransferase domain Lung_7-TM_R PF06814.13 PSC67979.1 - 2.1e-42 145.4 14.7 3e-42 144.9 14.7 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 PSC67979.1 - 1.3e-06 28.1 16.5 3.1e-06 26.8 16.4 1.7 1 1 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain DnaJ_C PF01556.18 PSC67980.1 - 5.8e-32 110.8 0.0 8.8e-32 110.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PSC67980.1 - 4.2e-23 81.2 3.2 6.6e-23 80.6 3.2 1.3 1 0 0 1 1 1 1 DnaJ domain WD40 PF00400.32 PSC67980.1 - 3.1e-05 24.6 1.0 0.25 12.3 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat LRR_4 PF12799.7 PSC67981.1 - 2.2e-16 59.7 0.0 0.16 12.5 0.0 8.4 7 2 1 9 9 9 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC67981.1 - 7.1e-10 38.5 3.9 0.06 13.1 0.0 7.3 6 4 1 7 7 7 4 Leucine rich repeat LRR_6 PF13516.6 PSC67981.1 - 2.1e-09 36.7 11.5 3.4 8.0 0.0 11.2 14 0 0 14 14 14 3 Leucine Rich repeat LRR_1 PF00560.33 PSC67981.1 - 0.0026 18.0 12.4 2.1 9.2 0.0 8.2 12 0 0 12 12 12 1 Leucine Rich Repeat DUF1375 PF07119.12 PSC67981.1 - 0.18 12.2 1.9 30 5.1 0.4 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1375) DUF1681 PF07933.14 PSC67983.1 - 2e-44 150.9 0.0 2.6e-44 150.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) ADAM_spacer1 PF05986.14 PSC67983.1 - 0.074 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 ADAM-TS Spacer 1 PRP38 PF03371.15 PSC67984.1 - 1.9e-56 190.7 0.0 2.4e-56 190.3 0.0 1.1 1 0 0 1 1 1 1 PRP38 family PRP38_assoc PF12871.7 PSC67984.1 - 0.0033 18.0 30.6 0.0033 18.0 30.6 3.3 1 1 2 3 3 3 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term SRP-alpha_N PF04086.13 PSC67984.1 - 0.094 12.6 20.8 0.12 12.3 20.8 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal BPL_LplA_LipB PF03099.19 PSC67985.1 - 6.5e-26 90.8 0.0 9.7e-26 90.2 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 PSC67985.1 - 1.3e-05 25.0 0.0 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain Alba PF01918.21 PSC67986.1 - 9.7e-19 67.0 1.0 1.4e-18 66.4 1.0 1.3 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 PSC67986.1 - 1.8e-05 24.7 0.0 2.2e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Rpp20 subunit of nuclear RNase MRP and P TPR_1 PF00515.28 PSC67987.1 - 8.2e-05 22.3 17.3 0.007 16.1 1.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 PSC67987.1 - 0.0081 15.8 5.0 0.059 13.1 0.6 2.8 2 0 0 2 2 2 1 TPR repeat TPR_17 PF13431.6 PSC67987.1 - 0.047 14.1 4.5 0.15 12.5 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat COMMD1_N PF17221.3 PSC67987.1 - 8 6.8 7.6 4.4 7.6 1.1 3.3 3 0 0 3 3 3 0 COMMD1 N-terminal domain Isochorismatase PF00857.20 PSC67988.1 - 2.3e-38 132.1 0.8 2.8e-38 131.8 0.8 1.0 1 0 0 1 1 1 1 Isochorismatase family Gmx_para_CXXCG PF09535.10 PSC67988.1 - 0.062 12.6 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (Gmx_para_CXXCG) Hyd_WA PF06462.12 PSC67988.1 - 2.5 8.2 6.1 5.8 7.0 6.1 1.9 1 1 0 1 1 1 0 Propeller Pkinase PF00069.25 PSC67989.1 - 1.3e-49 169.0 0.0 1.2e-33 116.7 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Bestrophin PF01062.21 PSC67989.1 - 2.1e-35 122.6 0.4 2.1e-35 122.6 0.4 2.1 2 0 0 2 2 2 1 Bestrophin, RFP-TM, chloride channel Pkinase_Tyr PF07714.17 PSC67989.1 - 9.9e-17 61.1 0.0 3.2e-14 52.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Ribosomal_L7Ae PF01248.26 PSC67989.1 - 4.9e-14 51.8 0.3 6.8e-06 25.7 0.1 3.0 3 0 0 3 3 3 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family zf-C2H2_2 PF12756.7 PSC67989.1 - 0.0001 22.5 0.0 0.51 10.7 0.0 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) Kdo PF06293.14 PSC67989.1 - 0.0086 15.5 0.7 0.018 14.4 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-met PF12874.7 PSC67989.1 - 0.016 15.6 0.1 0.034 14.5 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 PSC67989.1 - 0.052 14.4 0.6 2.4 9.3 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PSC67989.1 - 0.07 13.4 0.0 0.52 10.7 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 PSC67989.1 - 0.12 12.8 1.1 1.4 9.5 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type TFIIA PF03153.13 PSC67989.1 - 5.1 7.0 18.5 11 5.9 18.5 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pkinase PF00069.25 PSC67990.1 - 1.3e-49 169.0 0.0 1.2e-33 116.7 0.0 2.5 2 1 0 2 2 2 2 Protein kinase domain Bestrophin PF01062.21 PSC67990.1 - 2.1e-35 122.6 0.4 2.1e-35 122.6 0.4 2.1 2 0 0 2 2 2 1 Bestrophin, RFP-TM, chloride channel Pkinase_Tyr PF07714.17 PSC67990.1 - 9.9e-17 61.1 0.0 3.2e-14 52.8 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Ribosomal_L7Ae PF01248.26 PSC67990.1 - 5e-14 51.8 0.3 6.8e-06 25.7 0.1 3.0 3 0 0 3 3 3 2 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family zf-C2H2_2 PF12756.7 PSC67990.1 - 0.0001 22.5 0.0 0.51 10.7 0.0 2.5 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) Kdo PF06293.14 PSC67990.1 - 0.0086 15.5 0.7 0.018 14.4 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-met PF12874.7 PSC67990.1 - 0.016 15.6 0.1 0.034 14.5 0.1 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 PSC67990.1 - 0.052 14.4 0.6 2.4 9.3 0.1 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 PSC67990.1 - 0.07 13.4 0.0 0.52 10.7 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 PSC67990.1 - 0.12 12.8 1.1 1.4 9.5 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type TFIIA PF03153.13 PSC67990.1 - 5 7.0 18.5 11 5.9 18.5 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_16 PF10294.9 PSC67991.1 - 2.3e-22 79.6 0.0 3.8e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 PSC67991.1 - 4.7e-05 22.9 0.9 5.5e-05 22.7 0.0 1.5 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) DUF2722 PF10846.8 PSC67991.1 - 0.00038 19.5 0.1 0.00044 19.3 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Methyltransf_25 PF13649.6 PSC67991.1 - 0.00062 20.4 0.0 0.0038 17.9 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC67991.1 - 0.0008 20.1 0.3 0.0049 17.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain DUF2201_N PF13203.6 PSC67991.1 - 0.027 14.1 2.1 0.042 13.4 2.1 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Spt20 PF12090.8 PSC67991.1 - 0.14 11.8 11.5 0.2 11.2 11.5 1.2 1 0 0 1 1 1 0 Spt20 family DUF4834 PF16118.5 PSC67991.1 - 0.18 12.8 1.6 0.3 12.1 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Roughex PF06020.11 PSC67991.1 - 0.25 10.4 4.0 0.33 10.0 4.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein UPF0560 PF10577.9 PSC67991.1 - 0.74 8.2 5.7 0.98 7.8 5.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4175 PF13779.6 PSC67991.1 - 7.6 4.3 17.0 0.23 9.3 8.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) WD40 PF00400.32 PSC67992.1 - 3.9e-49 163.6 16.8 3.3e-08 34.1 0.0 8.0 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC67992.1 - 3.7e-14 52.8 0.0 0.012 15.9 0.0 5.1 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PSC67992.1 - 5.3e-07 28.9 0.2 0.12 11.3 0.0 3.7 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PSC67992.1 - 0.00051 18.8 0.5 2.6 6.6 0.0 3.9 1 1 2 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 PSC67992.1 - 0.0021 17.4 0.0 2 7.7 0.0 2.3 1 1 1 2 2 2 2 WD40-like domain RRM_1 PF00076.22 PSC67994.1 - 1.8e-14 53.3 0.0 2.6e-14 52.8 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PSC67994.1 - 0.025 14.2 0.1 0.081 12.5 0.0 1.8 2 1 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pinin_SDK_N PF04697.13 PSC67994.1 - 2.3 8.9 7.5 4 8.1 7.5 1.3 1 0 0 1 1 1 0 pinin/SDK conserved region Thioredoxin PF00085.20 PSC67995.1 - 5.5e-18 64.9 0.0 6e-18 64.7 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PSC67995.1 - 4.6e-05 23.8 0.2 0.00015 22.2 0.2 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PSC67995.1 - 5.6e-05 23.4 0.0 7.3e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 PSC67995.1 - 0.0011 18.9 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 PSC67995.1 - 0.016 15.0 0.0 0.019 14.8 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.10 PSC67995.1 - 0.044 13.5 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Redoxin UPF0047 PF01894.17 PSC67996.1 - 5.9e-20 71.5 0.0 9.6e-20 70.9 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 FmdA_AmdA PF03069.15 PSC67996.1 - 2.3e-16 59.6 0.1 5.4e-16 58.4 0.1 1.5 1 1 0 1 1 1 1 Acetamidase/Formamidase family DUF4947 PF16305.5 PSC67996.1 - 0.11 12.5 0.0 0.18 11.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4947) DAO PF01266.24 PSC67997.1 - 2.5e-41 142.4 9.2 8.6e-41 140.7 9.2 1.7 1 1 0 1 1 1 1 FAD dependent oxidoreductase Toprim_3 PF13362.6 PSC67997.1 - 0.2 12.0 1.3 25 5.3 0.2 2.6 1 1 1 2 2 2 0 Toprim domain CLASP_N PF12348.8 PSC67998.1 - 1.2e-09 38.0 0.4 0.00033 20.3 0.1 5.4 6 0 0 6 6 6 3 CLASP N terminal HEAT PF02985.22 PSC67998.1 - 6.4e-07 29.1 21.2 0.48 10.8 0.2 10.0 11 0 0 11 11 11 3 HEAT repeat HEAT_2 PF13646.6 PSC67998.1 - 4e-05 23.9 44.6 0.0094 16.3 0.1 9.7 9 1 1 10 10 10 3 HEAT repeats Spore_YpjB PF09577.10 PSC67998.1 - 0.14 11.9 0.1 0.38 10.5 0.1 1.6 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) TAN PF11640.8 PSC67998.1 - 0.15 12.2 0.4 2.8 8.0 0.0 3.4 4 0 0 4 4 4 0 Telomere-length maintenance and DNA damage repair IFRD PF05004.13 PSC67998.1 - 1.6 7.7 5.0 9.1 5.3 0.1 3.3 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) HECT PF00632.25 PSC67999.1 - 2.9e-45 155.1 0.0 3.5e-25 89.1 0.0 2.1 1 1 1 2 2 2 2 HECT-domain (ubiquitin-transferase) Ank_2 PF12796.7 PSC67999.1 - 3.3e-32 110.9 11.4 1.7e-11 44.5 0.0 5.0 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PSC67999.1 - 8.6e-20 68.8 14.4 0.0082 16.6 0.0 9.7 9 0 0 9 9 9 5 Ankyrin repeat Ank PF00023.30 PSC67999.1 - 5e-17 61.5 31.4 0.00082 19.7 0.1 9.7 10 0 0 10 10 10 6 Ankyrin repeat Ank_5 PF13857.6 PSC67999.1 - 4.5e-16 58.7 19.3 4e-08 33.4 0.1 6.7 3 2 4 7 7 7 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC67999.1 - 7e-15 55.2 12.4 0.0019 18.7 0.0 6.8 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Spt20 PF12090.8 PSC67999.1 - 1.1 8.9 3.4 2.1 7.9 3.4 1.4 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 PSC67999.1 - 1.8 8.4 12.0 3.4 7.6 12.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pro_isomerase PF00160.21 PSC68000.1 - 8.6e-32 110.6 0.0 1e-31 110.3 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Fis1_TPR_C PF14853.6 PSC68001.1 - 1.1e-16 60.6 1.8 1.6e-16 60.1 0.3 2.0 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Fis1_TPR_N PF14852.6 PSC68001.1 - 1.1e-08 34.6 0.0 2.1e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Fis1 N-terminal tetratricopeptide repeat TPR_6 PF13174.6 PSC68001.1 - 0.011 16.3 0.2 0.07 13.8 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 PSC68001.1 - 0.13 13.1 0.2 0.13 13.1 0.2 2.8 3 1 1 4 4 4 0 Tetratricopeptide repeat Y_phosphatase3 PF13350.6 PSC68002.1 - 1.8e-37 129.5 0.0 2.3e-37 129.2 0.0 1.1 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 PSC68002.1 - 0.11 12.1 0.0 0.65 9.6 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family PNRC PF15365.6 PSC68002.1 - 5.8 6.9 7.1 0.75 9.7 1.8 2.1 2 0 0 2 2 2 0 Proline-rich nuclear receptor coactivator motif Rad17 PF03215.15 PSC68004.1 - 6.1e-18 65.4 0.0 1.7e-17 64.0 0.0 1.6 2 0 0 2 2 2 1 Rad17 P-loop domain AP_endonuc_2 PF01261.24 PSC68004.1 - 0.0024 17.3 0.0 0.0093 15.4 0.0 1.9 1 1 1 2 2 2 1 Xylose isomerase-like TIM barrel AAA_16 PF13191.6 PSC68004.1 - 0.0029 18.0 1.9 0.014 15.8 0.6 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.6 PSC68004.1 - 0.0033 17.7 0.0 0.15 12.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 PSC68004.1 - 0.026 15.1 0.0 0.049 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PSC68004.1 - 0.052 13.5 0.0 1.5 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 PSC68004.1 - 0.053 13.7 0.0 0.81 9.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 PSC68004.1 - 0.061 12.6 0.0 0.16 11.2 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin TsaE PF02367.17 PSC68004.1 - 0.091 12.8 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA PF00004.29 PSC68004.1 - 0.096 13.1 0.0 0.2 12.1 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 PSC68004.1 - 0.14 12.4 0.0 0.38 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 PSC68004.1 - 0.18 12.3 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 PSC68005.1 - 1e-35 123.1 0.0 1.6e-35 122.5 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC68005.1 - 2.2e-20 73.0 0.0 4.4e-20 72.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC68005.1 - 7.9e-05 22.7 0.0 0.00022 21.3 0.0 1.7 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit Nha1_C PF08619.10 PSC68005.1 - 0.079 12.2 7.1 0.13 11.4 7.1 1.3 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus SecA_DEAD PF07517.14 PSC68005.1 - 0.14 11.4 0.1 0.31 10.3 0.0 1.5 2 0 0 2 2 2 0 SecA DEAD-like domain CMS1 PF14617.6 PSC68005.1 - 2 7.7 3.8 38 3.5 2.9 2.4 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 PSC68006.1 - 1.6e-45 155.0 0.0 3.1e-45 154.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC68006.1 - 3.1e-24 85.4 0.0 9.5e-24 83.9 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 PSC68006.1 - 1.4e-20 73.2 0.4 2.8e-20 72.3 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 PSC68006.1 - 0.00075 19.5 0.1 0.0024 17.9 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit FAM60A PF15396.6 PSC68006.1 - 1.8 8.5 4.3 3.3 7.7 4.3 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Hus1 PF04005.12 PSC68007.1 - 5.1e-33 114.4 0.0 8.1e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 Hus1-like protein DNA_pol_A_exo1 PF01612.20 PSC68007.1 - 7.3e-32 110.5 0.0 1.7e-31 109.3 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 PSC68007.1 - 2.8e-05 24.0 0.2 0.00011 22.1 0.2 2.0 1 0 0 1 1 1 1 HRDC domain PAT1 PF09770.9 PSC68007.1 - 8.1 4.6 13.1 15 3.7 13.1 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 mTERF PF02536.14 PSC68008.1 - 8.9e-05 21.6 0.0 0.00015 20.8 0.0 1.4 1 0 0 1 1 1 1 mTERF RRM_1 PF00076.22 PSC68009.1 - 1.6e-14 53.4 0.0 2.3e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PTPLA PF04387.14 PSC68010.1 - 9e-59 197.9 8.2 9e-59 197.9 8.2 1.9 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA KDZ PF18758.1 PSC68010.1 - 2.8e-29 102.3 0.0 4.2e-29 101.8 0.0 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase UPF0126 PF03458.13 PSC68010.1 - 1.7 8.6 6.5 2.3 8.2 0.6 2.9 2 0 0 2 2 2 0 UPF0126 domain GCK PF07802.11 PSC68011.1 - 2.4e-24 85.6 3.8 3.7e-24 84.9 3.8 1.2 1 0 0 1 1 1 1 GCK domain DUF2946 PF11162.8 PSC68011.1 - 2.8 8.6 13.4 0.2 12.3 4.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) DUF4407 PF14362.6 PSC68012.1 - 6.8e-05 22.4 11.9 0.00015 21.3 11.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) Seryl_tRNA_N PF02403.22 PSC68012.1 - 0.031 14.5 3.1 4.8 7.5 1.4 2.7 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain THOC7 PF05615.13 PSC68012.1 - 0.043 14.1 7.5 1.5 9.1 0.5 2.7 2 0 0 2 2 2 0 Tho complex subunit 7 Spc7 PF08317.11 PSC68012.1 - 0.14 11.0 7.7 2.2 7.1 0.1 2.8 3 0 0 3 3 3 0 Spc7 kinetochore protein SOGA PF11365.8 PSC68012.1 - 0.15 13.2 2.6 2.1 9.5 0.1 3.2 2 1 1 3 3 3 0 Protein SOGA SlyX PF04102.12 PSC68012.1 - 0.22 12.1 8.8 0.31 11.7 1.3 3.5 3 1 0 3 3 3 0 SlyX GAS PF13851.6 PSC68012.1 - 0.3 10.4 3.2 2.9 7.2 0.2 2.4 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.8 PSC68012.1 - 0.47 10.5 4.8 0.66 10.0 1.0 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding WHEP-TRS PF00458.20 PSC68012.1 - 0.7 10.1 0.0 0.7 10.1 0.0 3.0 4 0 0 4 4 3 0 WHEP-TRS domain TPR_MLP1_2 PF07926.12 PSC68012.1 - 1.1 9.3 15.0 3 7.9 1.1 3.3 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 PSC68012.1 - 1.5 9.2 4.7 18 5.7 4.4 2.2 1 1 1 2 2 2 0 Fez1 ATG16 PF08614.11 PSC68012.1 - 1.6 8.9 11.2 15 5.7 11.2 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) AAA_13 PF13166.6 PSC68012.1 - 1.7 7.2 7.6 6.1 5.4 2.1 2.1 1 1 0 2 2 2 0 AAA domain Uso1_p115_C PF04871.13 PSC68012.1 - 2.8 8.3 13.8 10 6.5 0.8 2.6 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region rve PF00665.26 PSC68013.1 - 2.9e-19 69.4 0.0 7.6e-19 68.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC68013.1 - 0.0064 16.2 0.0 0.016 15.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain AAA_25 PF13481.6 PSC68013.1 - 0.016 14.7 2.5 2.3 7.7 0.3 3.3 2 1 0 2 2 2 0 AAA domain Ribosomal_L30 PF00327.20 PSC68015.1 - 3.1e-13 49.4 0.5 3.9e-13 49.0 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e WLM PF08325.10 PSC68016.1 - 1.1e-41 143.1 0.0 1.8e-41 142.3 0.0 1.3 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 PSC68016.1 - 0.008 16.2 1.0 0.059 13.4 0.7 2.1 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.9 PSC68016.1 - 0.011 15.6 0.0 0.019 14.8 0.0 1.4 1 0 0 1 1 1 0 SprT-like family ubiquitin PF00240.23 PSC68016.1 - 0.022 14.5 0.0 0.047 13.4 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin family YukD PF08817.10 PSC68016.1 - 0.091 13.5 0.1 0.39 11.4 0.1 2.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD FeoA PF04023.14 PSC68016.1 - 0.12 12.7 0.2 0.61 10.4 0.1 2.3 1 1 1 2 2 2 0 FeoA domain Shadoo PF14999.6 PSC68016.1 - 0.29 11.2 12.3 1.7 8.8 0.3 2.7 2 0 0 2 2 2 0 Shadow of prion protein, neuroprotective Peptidase_M20 PF01546.28 PSC68017.1 - 1.4e-20 73.9 0.0 2e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PSC68017.1 - 1.4e-17 63.6 0.0 2.5e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain adh_short_C2 PF13561.6 PSC68018.1 - 2.3e-38 132.1 0.7 2.6e-29 102.4 0.1 2.6 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PSC68018.1 - 2.5e-34 118.4 0.0 3.6e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PSC68018.1 - 2.1e-06 27.8 0.1 4.6e-06 26.7 0.1 1.5 1 0 0 1 1 1 1 KR domain SNF5 PF04855.12 PSC68019.1 - 1.3e-20 74.2 2.3 1.5e-13 51.1 0.0 3.2 1 1 2 3 3 3 2 SNF5 / SMARCB1 / INI1 BSP_II PF05432.11 PSC68019.1 - 5.1 6.7 10.2 8.1 6.0 10.2 1.3 1 1 0 1 1 1 0 Bone sialoprotein II (BSP-II) SURF2 PF05477.11 PSC68019.1 - 8.6 6.0 10.3 14 5.2 10.3 1.3 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) bZIP_2 PF07716.15 PSC68020.1 - 0.0024 17.9 7.4 0.0024 17.9 7.4 3.5 4 0 0 4 4 4 1 Basic region leucine zipper MMR1 PF08505.10 PSC68020.1 - 3 8.0 18.4 0.37 11.0 7.2 2.5 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Pkinase PF00069.25 PSC68021.1 - 4.1e-54 183.7 0.0 5.9e-54 183.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC68021.1 - 1.8e-34 119.2 0.0 2.7e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC68021.1 - 2.2e-05 23.9 0.0 9.7e-05 21.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Adaptin_N PF01602.20 PSC68021.1 - 0.0007 18.3 0.0 0.0015 17.1 0.0 1.5 2 0 0 2 2 2 1 Adaptin N terminal region HDA2-3 PF11496.8 PSC68021.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 APH PF01636.23 PSC68021.1 - 0.022 14.7 0.2 0.022 14.7 0.2 3.8 3 0 0 3 3 3 0 Phosphotransferase enzyme family Cnd1 PF12717.7 PSC68021.1 - 0.16 12.0 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Kdo PF06293.14 PSC68021.1 - 0.22 10.8 0.0 0.4 10.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RICTOR_N PF14664.6 PSC68021.1 - 0.66 8.9 3.1 8.8 5.2 0.4 2.8 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term HEAT_2 PF13646.6 PSC68021.1 - 3.8 8.0 41.3 13 6.2 4.4 6.2 4 1 1 5 5 5 0 HEAT repeats Pkinase PF00069.25 PSC68022.1 - 4.2e-54 183.7 0.0 5.9e-54 183.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC68022.1 - 1.8e-34 119.2 0.0 2.7e-34 118.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC68022.1 - 2.2e-05 23.9 0.0 9.7e-05 21.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Adaptin_N PF01602.20 PSC68022.1 - 0.0007 18.3 0.0 0.0015 17.1 0.0 1.5 2 0 0 2 2 2 1 Adaptin N terminal region HDA2-3 PF11496.8 PSC68022.1 - 0.015 14.5 0.0 0.024 13.8 0.0 1.2 1 0 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 APH PF01636.23 PSC68022.1 - 0.022 14.7 0.2 0.022 14.7 0.2 3.8 3 0 0 3 3 3 0 Phosphotransferase enzyme family Cnd1 PF12717.7 PSC68022.1 - 0.17 12.0 0.0 0.39 10.8 0.0 1.6 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 Kdo PF06293.14 PSC68022.1 - 0.22 10.8 0.0 0.4 10.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RICTOR_N PF14664.6 PSC68022.1 - 0.66 8.9 3.1 8.9 5.2 0.4 2.8 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, N-term ATG16 PF08614.11 PSC68023.1 - 0.023 15.0 1.4 0.027 14.7 1.4 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4427 PF14468.6 PSC68023.1 - 0.03 14.4 0.1 0.034 14.2 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) LCIB_C_CA PF18599.1 PSC68026.1 - 4.2e-75 251.9 1.0 6.4e-75 251.3 0.0 1.8 2 0 0 2 2 2 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF563 PF04577.14 PSC68026.1 - 2e-22 80.4 0.0 2.7e-21 76.7 0.0 2.8 4 0 0 4 4 4 1 Protein of unknown function (DUF563) DUF962 PF06127.11 PSC68026.1 - 1.3e-19 70.0 5.0 3.1e-19 68.8 4.5 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF962) DUF2722 PF10846.8 PSC68026.1 - 0.6 9.0 6.4 0.88 8.4 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) eIF-3_zeta PF05091.12 PSC68026.1 - 0.7 8.8 3.5 1 8.3 3.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Exo_endo_phos PF03372.23 PSC68027.1 - 1.7e-14 53.9 0.1 2.6e-14 53.3 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family FAP PF07174.11 PSC68027.1 - 0.14 11.6 18.5 0.23 10.9 18.5 1.3 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) MIP PF00230.20 PSC68029.1 - 1.9e-08 34.3 14.9 2.7e-08 33.8 14.9 1.2 1 0 0 1 1 1 1 Major intrinsic protein BSP PF04450.12 PSC68029.1 - 0.16 11.7 0.1 0.25 11.1 0.1 1.2 1 0 0 1 1 1 0 Peptidase of plants and bacteria DUF4427 PF14468.6 PSC68029.1 - 0.29 11.2 0.7 0.51 10.4 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) Amino_oxidase PF01593.24 PSC68030.1 - 3.8e-59 201.2 8.4 3.8e-58 197.9 8.4 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PSC68030.1 - 8.7e-12 45.1 2.4 8.7e-12 45.1 2.4 2.1 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 PSC68030.1 - 4.5e-06 25.6 0.3 0.00015 20.7 0.8 2.1 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.17 PSC68030.1 - 3.6e-05 23.1 0.2 7.2e-05 22.1 0.2 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 PSC68030.1 - 7.5e-05 22.1 1.0 0.021 14.1 1.2 2.4 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PSC68030.1 - 0.0002 21.0 9.9 0.0019 17.9 9.9 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PSC68030.1 - 0.00026 20.2 1.9 0.00046 19.4 1.9 1.4 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 PSC68030.1 - 0.00035 19.9 0.7 0.0013 18.1 0.3 1.9 2 0 0 2 2 2 1 FAD binding domain FAD_oxidored PF12831.7 PSC68030.1 - 0.00047 19.6 5.3 0.00087 18.7 5.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 PSC68030.1 - 0.0024 17.0 3.7 0.068 12.2 0.8 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 PSC68030.1 - 0.0031 17.5 0.9 0.59 10.1 0.0 2.4 2 0 0 2 2 2 1 FAD-NAD(P)-binding Pyr_redox_3 PF13738.6 PSC68030.1 - 0.022 14.0 0.1 0.34 10.1 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PSC68030.1 - 0.043 12.9 3.4 0.031 13.3 1.0 2.0 2 0 0 2 2 2 0 Glucose inhibited division protein A Pyr_redox PF00070.27 PSC68030.1 - 0.06 13.9 0.2 0.87 10.2 0.3 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 PSC68030.1 - 0.15 11.3 3.2 0.18 11.1 1.0 2.1 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MBF1 PF08523.10 PSC68031.1 - 5.3e-17 62.0 4.4 5.3e-17 62.0 4.4 1.7 2 0 0 2 2 2 1 Multiprotein bridging factor 1 HTH_3 PF01381.22 PSC68031.1 - 1.1e-14 54.1 0.5 1.8e-14 53.5 0.5 1.4 1 0 0 1 1 1 1 Helix-turn-helix HTH_31 PF13560.6 PSC68031.1 - 1.8e-05 25.0 0.0 4.1e-05 23.8 0.0 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_19 PF12844.7 PSC68031.1 - 2.8e-05 24.1 0.3 5e-05 23.3 0.1 1.5 2 0 0 2 2 2 1 Helix-turn-helix domain DHQS PF01959.16 PSC68031.1 - 0.089 11.7 1.4 0.1 11.5 1.4 1.0 1 0 0 1 1 1 0 3-dehydroquinate synthase II Colicin-DNase PF12639.7 PSC68031.1 - 0.22 12.4 1.3 0.36 11.7 1.1 1.4 1 1 0 1 1 1 0 DNase/tRNase domain of colicin-like bacteriocin FAM76 PF16046.5 PSC68032.1 - 9.5e-05 21.9 3.9 9.5e-05 21.9 3.9 1.4 1 1 0 1 1 1 1 FAM76 protein Spc7 PF08317.11 PSC68032.1 - 9.7e-05 21.4 12.6 0.00013 21.0 12.6 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Flagellin_C PF00700.21 PSC68032.1 - 0.00034 20.9 12.6 0.0014 19.0 0.6 3.2 2 1 2 4 4 3 2 Bacterial flagellin C-terminal helical region DUF812 PF05667.11 PSC68032.1 - 0.00042 19.4 3.3 0.00044 19.3 3.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) CALCOCO1 PF07888.11 PSC68032.1 - 0.00057 18.9 18.8 0.00068 18.6 18.8 1.0 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3450 PF11932.8 PSC68032.1 - 0.00079 18.8 12.1 0.0011 18.3 12.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) Golgin_A5 PF09787.9 PSC68032.1 - 0.0012 18.4 6.9 0.0015 18.0 6.9 1.1 1 0 0 1 1 1 1 Golgin subfamily A member 5 KASH_CCD PF14662.6 PSC68032.1 - 0.0013 18.6 12.4 0.0018 18.1 12.4 1.1 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH Fez1 PF06818.15 PSC68032.1 - 0.0026 18.2 10.9 0.0035 17.8 10.9 1.1 1 0 0 1 1 1 1 Fez1 Leu_zip PF15294.6 PSC68032.1 - 0.0048 16.4 3.8 0.0061 16.1 3.8 1.0 1 0 0 1 1 1 1 Leucine zipper CC2-LZ PF16516.5 PSC68032.1 - 0.0054 17.1 7.6 0.013 15.9 5.8 2.0 1 1 1 2 2 2 1 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DivIC PF04977.15 PSC68032.1 - 0.0056 16.4 4.7 0.0056 16.4 4.7 3.1 1 1 2 3 3 3 1 Septum formation initiator HMMR_N PF15905.5 PSC68032.1 - 0.0088 15.5 8.9 0.012 15.1 8.9 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal FlxA PF14282.6 PSC68032.1 - 0.009 16.0 11.9 0.009 16.0 11.9 1.9 1 1 1 2 2 2 1 FlxA-like protein Tropomyosin PF00261.20 PSC68032.1 - 0.0093 15.4 8.1 0.0093 15.4 8.1 2.1 1 1 1 2 2 2 1 Tropomyosin TPR_MLP1_2 PF07926.12 PSC68032.1 - 0.01 15.9 21.9 0.023 14.7 13.1 2.1 1 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-H PF05837.12 PSC68032.1 - 0.012 16.0 11.8 0.012 16.0 11.8 1.7 1 1 1 2 2 2 0 Centromere protein H (CENP-H) COG2 PF06148.11 PSC68032.1 - 0.013 15.6 8.8 0.41 10.7 4.0 2.2 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4407 PF14362.6 PSC68032.1 - 0.019 14.3 10.2 0.026 13.9 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1664 PF07889.12 PSC68032.1 - 0.019 15.0 4.7 0.086 12.9 1.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) APG6_N PF17675.1 PSC68032.1 - 0.023 15.2 19.3 0.1 13.1 19.3 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region TMF_DNA_bd PF12329.8 PSC68032.1 - 0.026 14.5 13.1 0.093 12.7 0.7 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 PSC68032.1 - 0.027 14.7 22.2 0.021 15.1 18.8 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) HemX PF04375.14 PSC68032.1 - 0.03 13.6 16.8 0.055 12.7 16.8 1.5 1 1 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Exonuc_VII_L PF02601.15 PSC68032.1 - 0.03 13.9 9.1 0.036 13.6 9.1 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit ABC_tran_CTD PF16326.5 PSC68032.1 - 0.035 14.4 16.0 0.1 12.9 2.3 2.5 1 1 1 2 2 2 0 ABC transporter C-terminal domain GAS PF13851.6 PSC68032.1 - 0.036 13.4 11.6 0.14 11.4 11.6 1.9 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding Baculo_PEP_C PF04513.12 PSC68032.1 - 0.036 14.1 7.4 0.16 12.0 7.5 1.7 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus Tup_N PF08581.10 PSC68032.1 - 0.038 14.3 5.2 0.12 12.7 2.3 2.1 2 0 0 2 2 2 0 Tup N-terminal Filament PF00038.21 PSC68032.1 - 0.041 13.5 14.2 0.85 9.1 14.3 1.9 1 1 0 1 1 1 0 Intermediate filament protein DUF5082 PF16888.5 PSC68032.1 - 0.042 14.1 15.2 0.059 13.7 4.9 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) HalX PF08663.10 PSC68032.1 - 0.043 14.1 19.5 0.65 10.4 1.8 2.9 1 1 2 3 3 3 0 HalX domain HIP1_clath_bdg PF16515.5 PSC68032.1 - 0.047 14.3 15.7 0.52 11.0 15.8 2.1 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Bacillus_HBL PF05791.11 PSC68032.1 - 0.051 13.4 4.6 0.04 13.7 2.8 1.6 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) NPV_P10 PF05531.12 PSC68032.1 - 0.052 14.0 5.9 0.17 12.4 0.9 2.5 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Syntaxin-6_N PF09177.11 PSC68032.1 - 0.053 14.1 9.3 0.46 11.1 9.2 2.0 1 1 0 1 1 1 0 Syntaxin 6, N-terminal AAA_13 PF13166.6 PSC68032.1 - 0.057 12.1 4.7 0.071 11.8 4.7 1.1 1 0 0 1 1 1 0 AAA domain CENP-F_leu_zip PF10473.9 PSC68032.1 - 0.059 13.4 9.9 0.11 12.5 9.9 1.3 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Atg14 PF10186.9 PSC68032.1 - 0.063 12.4 13.9 0.35 9.9 14.1 1.8 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FliJ PF02050.16 PSC68032.1 - 0.07 13.4 18.6 0.053 13.7 14.2 2.0 1 1 1 2 2 2 0 Flagellar FliJ protein MPS2 PF17060.5 PSC68032.1 - 0.075 12.3 0.3 0.091 12.0 0.3 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 DHR10 PF18595.1 PSC68032.1 - 0.077 13.1 20.0 1 9.4 18.6 2.1 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain TMF_TATA_bd PF12325.8 PSC68032.1 - 0.086 13.1 16.0 0.31 11.3 9.1 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding DUF948 PF06103.11 PSC68032.1 - 0.1 12.9 1.3 0.12 12.7 0.4 1.5 2 0 0 2 2 1 0 Bacterial protein of unknown function (DUF948) Prefoldin_2 PF01920.20 PSC68032.1 - 0.1 12.6 13.4 0.29 11.1 1.9 3.0 1 1 2 3 3 3 0 Prefoldin subunit Jnk-SapK_ap_N PF09744.9 PSC68032.1 - 0.1 12.8 16.5 0.14 12.3 11.3 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF3584 PF12128.8 PSC68032.1 - 0.11 10.0 15.3 0.23 8.9 15.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF4795 PF16043.5 PSC68032.1 - 0.12 12.0 7.2 0.23 11.0 7.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Sec2p PF06428.11 PSC68032.1 - 0.13 12.3 15.2 0.095 12.7 2.1 3.0 1 1 2 3 3 3 0 GDP/GTP exchange factor Sec2p FapA PF03961.13 PSC68032.1 - 0.16 10.6 2.4 0.2 10.2 2.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Phage_GP20 PF06810.11 PSC68032.1 - 0.19 11.5 5.1 0.23 11.2 4.8 1.3 1 1 0 1 1 1 0 Phage minor structural protein GP20 EzrA PF06160.12 PSC68032.1 - 0.19 9.9 8.0 0.24 9.5 8.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA DUF3618 PF12277.8 PSC68032.1 - 0.19 12.0 17.2 1.9 8.8 0.2 4.6 2 2 2 4 4 4 0 Protein of unknown function (DUF3618) Sec20 PF03908.13 PSC68032.1 - 0.19 11.6 2.4 0.24 11.4 1.3 1.8 1 1 0 1 1 1 0 Sec20 BLOC1_2 PF10046.9 PSC68032.1 - 0.21 11.9 7.7 0.53 10.6 5.2 2.3 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 LURAP PF14854.6 PSC68032.1 - 0.22 11.5 3.4 0.33 10.9 3.4 1.2 1 0 0 1 1 1 0 Leucine rich adaptor protein Prefoldin PF02996.17 PSC68032.1 - 0.23 11.4 10.3 0.78 9.7 2.4 2.7 2 1 1 3 3 3 0 Prefoldin subunit CEP209_CC5 PF16574.5 PSC68032.1 - 0.26 11.5 9.1 1.5 9.0 5.7 2.6 1 1 2 3 3 3 0 Coiled-coil region of centrosome protein CE290 Tropomyosin_1 PF12718.7 PSC68032.1 - 0.27 11.4 14.0 1.9 8.6 13.9 1.9 1 1 0 1 1 1 0 Tropomyosin like MscS_porin PF12795.7 PSC68032.1 - 0.3 10.6 30.8 2.2 7.8 30.9 1.9 1 1 0 1 1 1 0 Mechanosensitive ion channel porin domain IFT57 PF10498.9 PSC68032.1 - 0.31 10.0 8.1 0.14 11.1 4.9 1.6 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 Not3 PF04065.15 PSC68032.1 - 0.32 10.4 4.8 0.5 9.8 4.7 1.3 1 1 0 1 1 1 0 Not1 N-terminal domain, CCR4-Not complex component ADIP PF11559.8 PSC68032.1 - 0.32 11.0 20.3 1.9 8.5 10.1 2.7 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Het-C PF07217.11 PSC68032.1 - 0.33 9.4 2.2 0.39 9.2 2.2 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Troponin PF00992.20 PSC68032.1 - 0.36 11.1 8.3 2.5 8.4 3.7 2.3 1 1 1 2 2 2 0 Troponin Cortex-I_coil PF09304.10 PSC68032.1 - 0.39 10.9 11.9 1.2 9.4 6.3 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF724 PF05266.14 PSC68032.1 - 0.4 10.5 7.7 0.66 9.8 7.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) FlaC_arch PF05377.11 PSC68032.1 - 0.4 11.1 4.5 55 4.3 0.2 3.1 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF4618 PF15397.6 PSC68032.1 - 0.41 10.0 9.0 0.45 9.9 4.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) HTH_34 PF13601.6 PSC68032.1 - 0.41 10.9 4.9 1.4 9.1 0.1 3.0 2 1 1 3 3 3 0 Winged helix DNA-binding domain V_ATPase_I PF01496.19 PSC68032.1 - 0.46 8.3 5.4 0.56 8.1 5.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MT PF12777.7 PSC68032.1 - 0.57 9.2 3.7 1.3 8.0 0.2 2.1 1 1 1 2 2 2 0 Microtubule-binding stalk of dynein motor TMCO5 PF14992.6 PSC68032.1 - 0.58 9.7 5.4 0.7 9.4 5.4 1.1 1 0 0 1 1 1 0 TMCO5 family Macoilin PF09726.9 PSC68032.1 - 0.61 8.6 7.5 0.68 8.4 7.5 1.0 1 0 0 1 1 1 0 Macoilin family DUF4201 PF13870.6 PSC68032.1 - 0.64 9.7 11.3 0.41 10.3 6.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) FliD_N PF02465.18 PSC68032.1 - 0.67 10.7 8.7 0.69 10.7 1.8 2.2 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Seryl_tRNA_N PF02403.22 PSC68032.1 - 0.68 10.2 9.6 0.37 11.1 6.5 1.8 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HrpB7 PF09486.10 PSC68032.1 - 0.71 10.3 21.0 1 9.7 19.9 2.0 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) KxDL PF10241.9 PSC68032.1 - 0.77 10.1 9.0 2.4 8.5 0.4 2.5 1 1 2 3 3 3 0 Uncharacterized conserved protein DASH_Dad2 PF08654.10 PSC68032.1 - 0.78 10.2 11.5 5.6 7.5 9.1 2.8 1 1 1 2 2 2 0 DASH complex subunit Dad2 UPF0242 PF06785.11 PSC68032.1 - 0.88 9.6 10.6 0.49 10.5 2.2 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus YscO-like PF16789.5 PSC68032.1 - 0.88 9.6 7.7 13 5.8 7.7 2.4 1 1 0 1 1 1 0 YscO-like protein Fzo_mitofusin PF04799.13 PSC68032.1 - 1.2 8.7 9.2 12 5.4 8.0 2.4 1 1 1 2 2 2 0 fzo-like conserved region DUF4140 PF13600.6 PSC68032.1 - 1.4 9.4 18.6 9 6.8 11.7 3.1 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Sec8_exocyst PF04048.14 PSC68032.1 - 1.4 8.8 9.8 7.2 6.5 4.1 2.4 1 1 2 3 3 3 0 Sec8 exocyst complex component specific domain THOC7 PF05615.13 PSC68032.1 - 1.4 9.2 16.6 3.2 8.0 16.6 1.5 1 1 0 1 1 1 0 Tho complex subunit 7 Fmp27_WPPW PF10359.9 PSC68032.1 - 1.6 7.4 7.0 2.3 7.0 7.0 1.2 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain APC_N_CC PF16689.5 PSC68032.1 - 1.7 8.7 14.3 0.22 11.6 3.5 2.9 3 0 0 3 3 2 0 Coiled-coil N-terminus of APC, dimerisation domain Spc24 PF08286.11 PSC68032.1 - 1.8 8.9 14.7 2.4 8.5 1.7 2.7 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4472 PF14739.6 PSC68032.1 - 1.8 9.3 12.7 0.68 10.7 8.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF4200 PF13863.6 PSC68032.1 - 1.9 8.9 11.9 7.5 7.0 7.3 2.5 1 1 0 2 2 2 0 Domain of unknown function (DUF4200) OmpH PF03938.14 PSC68032.1 - 2.1 8.7 15.4 18 5.6 15.4 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TolA_bind_tri PF16331.5 PSC68032.1 - 2.1 8.5 17.4 1.3 9.2 4.8 3.1 2 1 1 3 3 3 0 TolA binding protein trimerisation TMPIT PF07851.13 PSC68032.1 - 2.2 7.4 4.2 3.2 6.9 4.2 1.3 1 0 0 1 1 1 0 TMPIT-like protein MerR-DNA-bind PF09278.11 PSC68032.1 - 2.2 8.8 22.4 2.6 8.7 6.8 3.9 2 1 1 3 3 3 0 MerR, DNA binding GrpE PF01025.19 PSC68032.1 - 2.5 7.7 9.4 14 5.3 3.7 2.1 1 1 1 2 2 2 0 GrpE Lectin_N PF03954.14 PSC68032.1 - 2.5 7.8 12.8 27 4.5 12.7 2.2 1 1 0 1 1 1 0 Hepatic lectin, N-terminal domain BRE1 PF08647.11 PSC68032.1 - 2.6 8.2 13.2 3.9 7.6 1.3 2.2 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase CLZ PF16526.5 PSC68032.1 - 2.8 8.3 16.5 4.6 7.7 3.4 3.1 1 1 2 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels YlqD PF11068.8 PSC68032.1 - 3.6 8.0 14.5 2.3 8.6 8.4 2.0 1 1 1 2 2 2 0 YlqD protein Nsp1_C PF05064.13 PSC68032.1 - 3.8 7.3 8.6 24 4.8 7.1 2.2 1 1 1 2 2 2 0 Nsp1-like C-terminal region YabA PF06156.13 PSC68032.1 - 4.7 7.9 7.5 39 4.9 7.5 2.1 1 1 0 1 1 1 0 Initiation control protein YabA HR1 PF02185.16 PSC68032.1 - 5.6 7.2 15.7 9.3 6.4 4.3 2.9 1 1 2 3 3 3 0 Hr1 repeat DUF4763 PF15960.5 PSC68032.1 - 5.7 6.2 11.6 25 4.1 2.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) ApoO PF09769.9 PSC68032.1 - 5.8 6.9 6.6 67 3.5 6.0 2.4 1 1 0 1 1 1 0 Apolipoprotein O BST2 PF16716.5 PSC68032.1 - 6.4 7.4 17.7 1.9 9.1 11.9 2.1 1 1 0 2 2 2 0 Bone marrow stromal antigen 2 DUF4349 PF14257.6 PSC68032.1 - 6.7 6.1 17.1 2.5 7.5 1.5 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4349) HAUS-augmin3 PF14932.6 PSC68032.1 - 7.5 6.0 17.4 19 4.7 17.4 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 DUF3138 PF11336.8 PSC68032.1 - 7.5 5.0 14.4 2e+02 0.3 14.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) ZapB PF06005.12 PSC68032.1 - 7.6 7.1 17.6 1.1e+02 3.3 17.6 2.5 1 1 0 1 1 1 0 Cell division protein ZapB M PF02370.16 PSC68032.1 - 8.5 7.3 19.2 5.9 7.8 4.0 4.7 2 1 4 6 6 4 0 M protein repeat FKBP_C PF00254.28 PSC68033.1 - 9.6e-17 61.1 0.0 1.4e-16 60.6 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RskA PF10099.9 PSC68033.1 - 0.047 14.0 9.4 0.065 13.5 9.4 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA CNOT11 PF10155.9 PSC68034.1 - 3.8e-17 62.6 0.0 5.1e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 11 Ras PF00071.22 PSC68035.1 - 8.7e-64 214.0 0.5 1e-63 213.7 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PSC68035.1 - 5.5e-36 123.4 0.2 7.8e-36 122.9 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PSC68035.1 - 3e-14 52.9 0.1 3.9e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PSC68035.1 - 1.7e-07 31.3 0.1 2.9e-07 30.6 0.1 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PSC68035.1 - 7.6e-05 22.7 2.1 0.023 14.6 0.2 2.1 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PSC68035.1 - 9.7e-05 22.0 0.2 0.00051 19.6 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PSC68035.1 - 0.00079 18.8 0.1 0.001 18.4 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 PSC68035.1 - 0.004 17.5 0.1 0.0071 16.8 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PSC68035.1 - 0.0042 17.4 0.1 0.029 14.6 0.1 2.2 1 1 0 1 1 1 1 AAA domain SRPRB PF09439.10 PSC68035.1 - 0.012 15.1 0.0 0.017 14.5 0.0 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 PSC68035.1 - 0.014 15.1 0.0 0.039 13.7 0.0 1.8 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 PSC68035.1 - 0.014 15.9 0.1 0.03 14.8 0.1 1.5 1 1 0 1 1 1 0 ABC transporter FeoB_N PF02421.18 PSC68035.1 - 0.018 14.6 0.1 0.07 12.6 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_24 PF13479.6 PSC68035.1 - 0.044 13.5 0.0 0.082 12.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 PSC68035.1 - 0.053 12.9 0.0 0.25 10.7 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 PSC68035.1 - 0.056 13.5 0.1 0.15 12.1 0.1 1.7 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 PSC68035.1 - 0.083 12.1 0.0 0.12 11.6 0.0 1.2 1 0 0 1 1 1 0 KAP family P-loop domain DUF3533 PF12051.8 PSC68035.1 - 0.13 11.1 0.2 0.16 10.9 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) AAA_7 PF12775.7 PSC68035.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_21 PF13304.6 PSC68035.1 - 0.18 11.6 0.6 0.22 11.3 0.5 1.4 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Tmemb_14 PF03647.13 PSC68036.1 - 7e-22 78.0 9.8 8.6e-22 77.7 9.8 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C SLATT_1 PF18181.1 PSC68036.1 - 0.46 10.4 2.1 0.44 10.5 0.4 1.8 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 KIAA1430 PF13879.6 PSC68037.1 - 7.5e-08 33.1 1.6 1.8e-07 31.9 1.6 1.7 1 0 0 1 1 1 1 KIAA1430 homologue Pkinase PF00069.25 PSC68038.1 - 2.1e-59 201.1 0.0 3.6e-53 180.6 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC68038.1 - 1.9e-32 112.5 0.0 8.5e-31 107.2 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Rep_fac_C PF08542.11 PSC68038.1 - 3.9e-15 56.0 0.0 8.1e-15 55.0 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 PSC68038.1 - 2.2e-14 54.0 0.0 4.7e-14 53.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HA PF03457.14 PSC68038.1 - 1.5e-12 47.6 1.4 6.8e-05 23.1 1.2 2.7 2 0 0 2 2 2 2 Helicase associated domain DNA_pol3_delta2 PF13177.6 PSC68038.1 - 2.9e-12 46.6 0.0 1.5e-09 37.8 0.0 2.3 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 PSC68038.1 - 1.2e-07 31.9 0.0 2.7e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 Rad17 P-loop domain Kinase-like PF14531.6 PSC68038.1 - 7.4e-06 25.5 0.0 1.2e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like cNMP_binding PF00027.29 PSC68038.1 - 9.9e-05 22.3 0.0 0.00096 19.2 0.0 2.5 2 0 0 2 2 2 1 Cyclic nucleotide-binding domain AAA_16 PF13191.6 PSC68038.1 - 0.00032 21.1 3.2 0.00086 19.7 0.0 3.5 3 1 0 3 3 2 1 AAA ATPase domain AAA_11 PF13086.6 PSC68038.1 - 0.00037 20.4 0.0 0.00087 19.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 PSC68038.1 - 0.001 18.9 0.0 0.008 15.9 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_3 PF07726.11 PSC68038.1 - 0.013 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 PSC68038.1 - 0.019 15.0 0.0 0.058 13.4 0.0 1.7 1 1 1 2 2 2 0 AAA domain ResIII PF04851.15 PSC68038.1 - 0.043 13.8 0.0 0.86 9.6 0.0 2.2 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 PSC68038.1 - 0.076 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_assoc_2 PF16193.5 PSC68038.1 - 0.077 13.3 0.0 0.28 11.5 0.0 2.0 1 0 0 1 1 1 0 AAA C-terminal domain AAA_5 PF07728.14 PSC68038.1 - 0.079 13.0 0.1 0.4 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 PSC68038.1 - 0.087 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PSC68038.1 - 0.1 12.9 0.2 1.6 9.0 0.2 2.5 1 1 0 1 1 1 0 AAA domain Seadorna_VP7 PF07387.11 PSC68038.1 - 0.11 11.5 0.0 0.22 10.5 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 DUF815 PF05673.13 PSC68038.1 - 0.12 11.6 0.0 0.24 10.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 PSC68038.1 - 0.14 12.7 0.0 0.33 11.5 0.0 1.5 1 0 0 1 1 1 0 ABC transporter RIO1 PF01163.22 PSC68038.1 - 0.25 10.9 0.0 0.49 10.0 0.0 1.4 1 0 0 1 1 1 0 RIO1 family bPH_2 PF03703.14 PSC68039.1 - 5.1e-08 33.0 0.0 2.4e-07 30.9 0.0 2.1 2 0 0 2 2 2 1 Bacterial PH domain DUF4395 PF14340.6 PSC68039.1 - 0.45 10.8 7.1 0.048 14.0 1.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) LYTB PF02401.18 PSC68040.1 - 5.1e-77 258.7 0.0 6.3e-77 258.4 0.0 1.1 1 0 0 1 1 1 1 LytB protein MFS_1 PF07690.16 PSC68041.1 - 1.7e-25 89.7 25.6 8.5e-23 80.8 23.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Trypsin PF00089.26 PSC68041.1 - 1.1e-15 58.0 0.1 1.7e-12 47.6 0.0 2.4 2 0 0 2 2 2 2 Trypsin SPO22 PF08631.10 PSC68041.1 - 1.3e-05 24.8 0.0 0.00023 20.7 0.1 2.6 3 0 0 3 3 3 1 Meiosis protein SPO22/ZIP4 like TPR_1 PF00515.28 PSC68041.1 - 0.0036 17.1 2.6 0.28 11.1 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 PSC68041.1 - 0.017 15.3 0.6 12 6.4 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 PSC68041.1 - 0.041 14.0 0.1 0.041 14.0 0.1 7.1 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_19 PF14559.6 PSC68041.1 - 0.09 13.3 0.0 0.09 13.3 0.0 8.4 8 2 0 8 8 8 0 Tetratricopeptide repeat DinB_2 PF12867.7 PSC68041.1 - 4.1 7.9 5.7 2.2 8.8 0.4 3.3 3 1 0 3 3 3 0 DinB superfamily adh_short PF00106.25 PSC68042.1 - 2.5e-24 85.8 0.1 2.8e-18 66.1 0.5 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PSC68042.1 - 5.3e-15 55.6 0.2 8.4e-14 51.7 0.2 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC68042.1 - 1.9e-06 27.9 1.6 3.4e-06 27.1 1.2 1.6 2 0 0 2 2 2 1 KR domain rve PF00665.26 PSC68043.1 - 7e-19 68.2 0.0 1.5e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC68043.1 - 0.0063 16.3 0.0 0.016 14.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Methyltransf_21 PF05050.12 PSC68045.1 - 4.2e-16 59.5 0.0 7.1e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase FkbM domain Glyco_tran_28_C PF04101.16 PSC68045.1 - 0.039 13.9 0.0 0.039 13.9 0.0 2.3 3 0 0 3 3 3 0 Glycosyltransferase family 28 C-terminal domain Presenilin PF01080.17 PSC68045.1 - 0.36 9.6 5.3 0.57 8.9 5.3 1.2 1 0 0 1 1 1 0 Presenilin CCDC53 PF10152.9 PSC68045.1 - 4.3 7.7 7.0 61 4.0 6.5 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex ABC_tran PF00005.27 PSC68046.1 - 1.3e-21 77.5 0.0 2.2e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 ABC transporter HMA PF00403.26 PSC68046.1 - 1.1e-12 48.1 0.2 2.3e-12 47.2 0.2 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain RsgA_GTPase PF03193.16 PSC68046.1 - 0.0019 18.1 0.1 0.0034 17.3 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 PSC68046.1 - 0.0072 16.7 0.1 0.021 15.2 0.1 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 PSC68046.1 - 0.022 14.5 0.0 0.4 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 PSC68046.1 - 0.078 13.2 0.0 0.2 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PSC68046.1 - 0.13 12.1 0.2 0.32 10.8 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain GPCR_chapero_1 PF11904.8 PSC68048.1 - 1.4e-28 100.3 0.0 8.7e-28 97.6 0.0 1.9 1 1 0 1 1 1 1 GPCR-chaperone zf-CCCH PF00642.24 PSC68048.1 - 5.1e-19 67.7 12.4 6.1e-11 41.9 2.3 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PSC68048.1 - 2.8e-10 39.9 13.5 1.9e-06 27.7 3.0 2.5 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 PSC68048.1 - 3.3e-09 36.3 7.4 3.1e-05 23.7 1.7 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger Ank_2 PF12796.7 PSC68048.1 - 3.6e-05 24.3 0.0 8.5e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC68048.1 - 0.00056 20.1 0.0 0.0016 18.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC68048.1 - 0.0066 17.0 0.0 0.064 13.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC68048.1 - 0.01 16.3 0.1 0.093 13.3 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat Ank PF00023.30 PSC68048.1 - 0.047 14.2 0.4 0.64 10.6 0.1 2.6 2 0 0 2 2 2 0 Ankyrin repeat Torus PF16131.5 PSC68048.1 - 0.11 13.2 2.2 0.15 12.8 0.1 2.1 2 0 0 2 2 2 0 Torus domain zf-CCCH_2 PF14608.6 PSC68048.1 - 0.67 10.5 8.2 0.92 10.1 2.7 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger RNA_pol_Rpb4 PF03874.16 PSC68049.1 - 9e-13 48.6 0.2 1.2e-12 48.2 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 TraB PF01963.17 PSC68049.1 - 0.071 13.0 2.2 0.14 12.1 0.4 1.9 1 1 1 2 2 2 0 TraB family RRM_1 PF00076.22 PSC68050.1 - 7.8e-14 51.3 0.0 1.3e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WD40 PF00400.32 PSC68050.1 - 1e-09 38.9 0.5 0.1 13.5 0.0 5.1 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC68050.1 - 1.1e-05 25.6 0.0 1.3 9.4 0.0 4.1 1 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PSC68050.1 - 0.05 12.6 0.0 0.17 10.8 0.0 1.7 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SDA1 PF05285.12 PSC68051.1 - 0.5 9.8 34.0 0.56 9.6 34.0 1.3 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 PSC68051.1 - 5.5 5.1 38.8 6.3 4.9 38.8 1.1 1 0 0 1 1 1 0 Nop14-like family Apt1 PF10351.9 PSC68051.1 - 6.7 5.4 7.8 7.1 5.4 7.8 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain SRP-alpha_N PF04086.13 PSC68051.1 - 8.6 6.2 18.4 9.2 6.1 18.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Reovirus_M2 PF05993.12 PSC68052.1 - 0.0059 14.8 0.8 0.0062 14.7 0.8 1.0 1 0 0 1 1 1 1 Reovirus major virion structural protein Mu-1/Mu-1C (M2) adh_short PF00106.25 PSC68053.1 - 1.9e-21 76.5 2.4 1.6e-12 47.3 0.1 2.5 2 0 0 2 2 2 2 short chain dehydrogenase LRR_8 PF13855.6 PSC68053.1 - 1.1e-16 60.4 10.7 0.00026 20.7 0.4 7.3 4 2 2 8 8 8 5 Leucine rich repeat LRR_4 PF12799.7 PSC68053.1 - 2.9e-15 56.1 2.1 0.3 11.6 0.0 8.2 4 2 6 10 10 10 8 Leucine Rich repeats (2 copies) adh_short_C2 PF13561.6 PSC68053.1 - 4.7e-10 39.4 6.7 5.4e-06 26.1 1.4 2.5 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase LRR_1 PF00560.33 PSC68053.1 - 0.0019 18.5 14.4 15 6.6 0.0 8.8 10 1 0 10 10 10 1 Leucine Rich Repeat DUF3987 PF13148.6 PSC68053.1 - 0.0064 15.6 6.9 0.013 14.5 6.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) LRR_6 PF13516.6 PSC68053.1 - 4 7.8 10.0 20 5.6 0.4 5.8 7 0 0 7 7 7 0 Leucine Rich repeat Lactamase_B_2 PF12706.7 PSC68054.1 - 6.4e-18 65.0 1.8 1.3e-17 64.0 1.8 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain fn3 PF00041.21 PSC68054.1 - 1.1e-17 64.1 0.0 0.0019 18.5 0.0 4.6 4 0 0 4 4 4 4 Fibronectin type III domain NUDIX PF00293.28 PSC68054.1 - 3.7e-17 62.6 0.5 7.3e-17 61.6 0.5 1.5 1 0 0 1 1 1 1 NUDIX domain BAF1_ABF1 PF04684.13 PSC68054.1 - 0.0079 15.3 8.3 0.017 14.2 8.3 1.4 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Pur_ac_phosph_N PF16656.5 PSC68054.1 - 0.041 14.4 0.1 53 4.5 0.0 4.2 4 0 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain Ndc1_Nup PF09531.10 PSC68054.1 - 4.5 5.8 16.3 7.6 5.1 16.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Lactamase_B_2 PF12706.7 PSC68055.1 - 6.4e-18 65.0 1.8 1.3e-17 64.0 1.8 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain fn3 PF00041.21 PSC68055.1 - 1.1e-17 64.1 0.0 0.0019 18.5 0.0 4.6 4 0 0 4 4 4 4 Fibronectin type III domain NUDIX PF00293.28 PSC68055.1 - 3.7e-17 62.6 0.5 7.3e-17 61.6 0.5 1.5 1 0 0 1 1 1 1 NUDIX domain BAF1_ABF1 PF04684.13 PSC68055.1 - 0.0079 15.3 8.3 0.017 14.2 8.3 1.4 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor Pur_ac_phosph_N PF16656.5 PSC68055.1 - 0.041 14.4 0.1 53 4.5 0.0 4.2 4 0 0 4 4 4 0 Purple acid Phosphatase, N-terminal domain Ndc1_Nup PF09531.10 PSC68055.1 - 4.5 5.8 16.3 7.6 5.1 16.3 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UPF0181 PF03701.14 PSC68056.1 - 0.11 12.2 0.1 0.11 12.2 0.1 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0181) Gpr1_Fun34_YaaH PF01184.19 PSC68057.1 - 1.7e-22 80.1 21.2 2.5e-22 79.5 21.2 1.2 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Ribosomal_L14 PF00238.19 PSC68058.1 - 2.1e-41 140.8 3.8 2.1e-41 140.8 3.8 1.5 2 0 0 2 2 2 1 Ribosomal protein L14p/L23e Chloroa_b-bind PF00504.21 PSC68059.1 - 4.3e-39 134.6 0.0 6.2e-39 134.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein IQ PF00612.27 PSC68060.1 - 0.00079 19.0 2.7 0.0028 17.3 2.7 2.0 1 0 0 1 1 1 1 IQ calmodulin-binding motif DEAD PF00270.29 PSC68061.1 - 6.6e-15 55.3 0.0 1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC68061.1 - 1.4e-14 54.4 0.0 2.6e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 PSC68061.1 - 9.1e-09 35.9 0.8 4.4e-08 33.7 0.8 2.2 2 0 0 2 2 2 1 RecQ zinc-binding Med3 PF11593.8 PSC68061.1 - 3.8e-06 26.4 1.5 3.8e-06 26.4 1.5 2.1 2 0 0 2 2 2 1 Mediator complex subunit 3 fungal DEAD PF00270.29 PSC68062.1 - 6.8e-15 55.3 0.0 1e-14 54.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC68062.1 - 1.4e-14 54.3 0.0 2.7e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RecQ_Zn_bind PF16124.5 PSC68062.1 - 9e-09 35.9 0.8 4.4e-08 33.7 0.8 2.2 2 0 0 2 2 2 1 RecQ zinc-binding Med3 PF11593.8 PSC68062.1 - 3.9e-06 26.3 1.5 3.9e-06 26.3 1.5 2.1 2 0 0 2 2 2 1 Mediator complex subunit 3 fungal Cpn60_TCP1 PF00118.24 PSC68063.1 - 2.5e-93 313.3 20.5 5.2e-93 312.3 20.5 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family WD40 PF00400.32 PSC68064.1 - 2.2e-21 75.7 8.6 4.5e-05 24.1 0.1 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC68064.1 - 1.4e-07 31.7 0.0 0.0076 16.5 0.1 4.8 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 PSC68064.1 - 0.022 13.3 1.8 3.1 6.2 0.1 2.5 2 1 0 2 2 2 0 Cytochrome D1 heme domain DUF5046 PF16465.5 PSC68064.1 - 0.025 14.0 0.4 0.31 10.4 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5046) PQQ_3 PF13570.6 PSC68064.1 - 0.028 14.9 0.2 0.46 11.0 0.1 2.8 2 0 0 2 2 2 0 PQQ-like domain PQQ PF01011.21 PSC68064.1 - 0.034 14.1 0.5 14 5.8 0.2 2.8 2 0 0 2 2 2 0 PQQ enzyme repeat DUF493 PF04359.14 PSC68065.1 - 1.4e-06 28.8 0.0 3.8e-06 27.4 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF493) AMH_N PF04709.12 PSC68065.1 - 0.05 12.5 0.0 0.078 11.9 0.0 1.3 1 0 0 1 1 1 0 Anti-Mullerian hormone, N terminal region C2 PF00168.30 PSC68066.1 - 5.8e-18 65.1 0.0 9.1e-14 51.6 0.0 2.8 3 0 0 3 3 3 2 C2 domain SMP_LBD PF17047.5 PSC68066.1 - 3.3e-15 56.0 0.1 5.3e-09 35.8 0.2 2.2 1 1 1 2 2 2 2 Synaptotagmin-like mitochondrial-lipid-binding domain DUF4381 PF14316.6 PSC68066.1 - 0.0065 16.7 1.1 0.0065 16.7 1.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) C2 PF00168.30 PSC68067.1 - 6.8e-19 68.1 0.0 9.2e-14 51.6 0.0 3.4 3 0 0 3 3 3 2 C2 domain SMP_LBD PF17047.5 PSC68067.1 - 1.4e-14 54.0 0.3 5.8e-09 35.7 0.3 2.2 2 0 0 2 2 2 2 Synaptotagmin-like mitochondrial-lipid-binding domain DUF4381 PF14316.6 PSC68067.1 - 0.0066 16.7 1.1 0.0066 16.7 1.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) SURF4 PF02077.15 PSC68068.1 - 7.7e-07 29.0 1.8 0.00037 20.2 0.0 2.4 2 1 0 2 2 2 2 SURF4 family ScdA_N PF04405.14 PSC68068.1 - 0.23 11.1 0.8 0.6 9.8 0.8 1.7 1 0 0 1 1 1 0 Domain of Unknown function (DUF542) DoxX PF07681.12 PSC68068.1 - 0.35 11.5 9.6 4.2 8.0 0.1 3.1 3 1 0 3 3 3 0 DoxX LANC_like PF05147.13 PSC68070.1 - 2.6e-44 151.3 0.0 6.5e-44 149.9 0.0 1.6 2 0 0 2 2 2 1 Lanthionine synthetase C-like protein tRNA_bind PF01588.20 PSC68070.1 - 8.1e-22 77.2 0.1 1.3e-21 76.5 0.1 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain DUF1180 PF06679.12 PSC68070.1 - 4.9 7.5 7.5 13 6.1 7.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) LANC_like PF05147.13 PSC68071.1 - 4.5e-47 160.3 0.0 5.8e-34 117.2 0.0 2.6 3 0 0 3 3 3 2 Lanthionine synthetase C-like protein tRNA_bind PF01588.20 PSC68071.1 - 8.5e-22 77.1 0.1 1.4e-21 76.4 0.1 1.3 1 0 0 1 1 1 1 Putative tRNA binding domain DUF1180 PF06679.12 PSC68071.1 - 5.2 7.4 7.5 14 6.0 7.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Metallophos PF00149.28 PSC68072.1 - 5.7e-07 30.2 0.0 9e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase F5_F8_type_C PF00754.25 PSC68072.1 - 3.1e-06 27.3 0.0 4.7e-05 23.5 0.0 2.9 3 1 0 3 3 3 1 F5/8 type C domain 5_nucleotid_C PF02872.18 PSC68072.1 - 5.8e-06 26.6 0.4 0.0003 21.0 0.1 2.6 1 1 1 2 2 2 1 5'-nucleotidase, C-terminal domain Phytase-like PF13449.6 PSC68072.1 - 0.00014 21.9 0.0 0.00069 19.6 0.0 2.2 1 1 0 1 1 1 1 Esterase-like activity of phytase PGA_cap PF09587.10 PSC68072.1 - 0.013 15.0 0.1 0.031 13.7 0.1 1.6 1 0 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap EstA_Ig_like PF18435.1 PSC68072.1 - 0.051 13.8 0.1 0.21 11.8 0.1 1.9 1 1 0 1 1 1 0 Esterase Ig-like N-terminal domain RRM_1 PF00076.22 PSC68073.1 - 1.4e-13 50.4 0.0 2.3e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BSP_II PF05432.11 PSC68073.1 - 0.012 15.3 5.1 0.018 14.7 5.1 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) THOC2_N PF16134.5 PSC68073.1 - 2 6.9 9.6 3.2 6.3 9.6 1.2 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Med15 PF09606.10 PSC68073.1 - 4.1 6.0 44.6 6.4 5.3 44.6 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SOBP PF15279.6 PSC68073.1 - 5 7.7 13.9 7.4 7.1 13.9 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Hamartin PF04388.12 PSC68073.1 - 7.9 5.0 13.5 11 4.5 13.5 1.1 1 0 0 1 1 1 0 Hamartin protein GST_N_3 PF13417.6 PSC68074.1 - 5.8e-15 55.5 0.0 1.1e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PSC68074.1 - 6.2e-13 48.9 0.0 1.8e-12 47.4 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PSC68074.1 - 4e-05 23.9 0.0 7.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tom37 PF10568.9 PSC68074.1 - 0.032 14.5 0.0 0.06 13.7 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 PSC68074.1 - 0.037 14.8 0.0 0.069 13.9 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain Glutaredoxin PF00462.24 PSC68074.1 - 0.088 13.0 0.0 0.25 11.6 0.0 1.8 1 0 0 1 1 1 0 Glutaredoxin Lipase_GDSL_2 PF13472.6 PSC68075.1 - 6.8e-10 39.6 0.0 1.4e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Bestrophin PF01062.21 PSC68075.1 - 1.8e-09 37.4 0.1 8.3e-06 25.4 0.0 2.2 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel DUF1826 PF08856.11 PSC68075.1 - 0.045 13.7 0.0 14 5.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1826) IGPD PF00475.18 PSC68075.1 - 0.11 12.9 0.3 24 5.2 0.0 2.3 2 0 0 2 2 2 0 Imidazoleglycerol-phosphate dehydratase TRAPP PF04051.16 PSC68076.1 - 8.9e-34 116.3 0.0 1.1e-33 116.0 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Proteasome PF00227.26 PSC68077.1 - 3e-62 209.5 0.0 4.6e-62 208.9 0.0 1.3 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 PSC68077.1 - 3.7e-10 39.3 1.2 4.6e-10 39.0 0.1 1.8 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Ferritin PF00210.24 PSC68079.1 - 3.1e-15 56.3 0.1 4.3e-15 55.9 0.1 1.1 1 0 0 1 1 1 1 Ferritin-like domain Solute_trans_a PF03619.16 PSC68080.1 - 5.1e-92 308.1 9.3 5.1e-92 308.1 9.3 1.5 2 0 0 2 2 2 1 Organic solute transporter Ostalpha Lipase_GDSL_2 PF13472.6 PSC68081.1 - 0.00027 21.4 0.1 0.00056 20.4 0.1 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Pectate_lyase_3 PF12708.7 PSC68082.1 - 1.5e-12 47.8 1.1 0.00028 20.8 0.0 4.6 4 0 0 4 4 4 3 Pectate lyase superfamily protein End_N_terminal PF12218.8 PSC68082.1 - 4.5 7.0 7.3 3.9 7.2 1.0 3.2 3 0 0 3 3 3 0 N terminal extension of bacteriophage endosialidase Pectate_lyase_3 PF12708.7 PSC68083.1 - 1.5e-12 47.8 1.1 0.00028 20.8 0.0 4.6 4 0 0 4 4 4 3 Pectate lyase superfamily protein End_N_terminal PF12218.8 PSC68083.1 - 4.5 7.0 7.3 3.9 7.2 1.0 3.2 3 0 0 3 3 3 0 N terminal extension of bacteriophage endosialidase AhpC-TSA PF00578.21 PSC68084.1 - 1.1e-38 131.9 0.0 2.1e-33 114.9 0.0 2.5 2 0 0 2 2 2 2 AhpC/TSA family rve PF00665.26 PSC68084.1 - 1.5e-20 73.5 0.0 4.4e-18 65.6 0.0 2.6 2 0 0 2 2 2 1 Integrase core domain Thioredoxin PF00085.20 PSC68084.1 - 2.6e-16 59.5 1.1 4.2e-16 58.8 0.1 1.8 2 0 0 2 2 2 1 Thioredoxin Redoxin PF08534.10 PSC68084.1 - 2.4e-15 56.5 0.0 8.1e-12 45.1 0.0 2.4 2 0 0 2 2 2 2 Redoxin Pkinase PF00069.25 PSC68084.1 - 6.1e-14 52.0 0.0 2.2e-13 50.2 0.0 1.7 1 1 1 2 2 2 1 Protein kinase domain 1-cysPrx_C PF10417.9 PSC68084.1 - 1.3e-12 47.3 0.5 1.8e-11 43.7 0.1 2.7 3 0 0 3 3 3 1 C-terminal domain of 1-Cys peroxiredoxin Pkinase_Tyr PF07714.17 PSC68084.1 - 2.3e-10 40.2 0.0 5.1e-10 39.1 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Thioredoxin_8 PF13905.6 PSC68084.1 - 0.0023 18.2 0.0 0.007 16.7 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 PSC68084.1 - 0.007 16.8 0.0 0.022 15.2 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain rve_3 PF13683.6 PSC68084.1 - 0.016 15.0 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain DUF1840 PF08895.11 PSC68084.1 - 0.059 13.7 3.8 0.22 11.9 3.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Nop PF01798.18 PSC68085.1 - 1e-85 286.9 0.1 1e-85 286.9 0.1 1.7 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 PSC68085.1 - 6e-20 71.4 2.7 6e-20 71.4 2.7 2.1 2 0 0 2 2 2 1 NOP5NT (NUC127) domain RNA_polI_A34 PF08208.11 PSC68085.1 - 0.15 12.2 32.9 0.29 11.2 32.9 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 PSC68085.1 - 5 6.9 14.7 9.6 5.9 14.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rieske PF00355.26 PSC68086.1 - 5.1e-10 39.2 0.0 1.5e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Abhydrolase_1 PF00561.20 PSC68086.1 - 2.1e-09 37.4 0.1 1.4e-07 31.5 0.1 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC68086.1 - 3.4e-05 23.2 0.0 0.00036 19.9 0.0 2.2 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Rieske_2 PF13806.6 PSC68086.1 - 7.9e-05 22.5 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain zf-C3HC4_3 PF13920.6 PSC68086.1 - 0.00015 21.5 5.8 0.00015 21.5 5.8 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Ribosomal_L7Ae PF01248.26 PSC68086.1 - 0.00033 20.3 0.1 0.0008 19.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family zf-C2H2_jaz PF12171.8 PSC68086.1 - 0.061 13.6 0.8 0.15 12.4 0.8 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Dev_Cell_Death PF10539.9 PSC68086.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Development and cell death domain Prok-RING_4 PF14447.6 PSC68086.1 - 0.82 9.6 7.7 2.7 7.9 7.7 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Rieske PF00355.26 PSC68087.1 - 5e-10 39.2 0.0 1.5e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Abhydrolase_1 PF00561.20 PSC68087.1 - 2e-09 37.5 0.1 1.4e-07 31.4 0.0 2.3 1 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC68087.1 - 3.4e-05 23.2 0.0 0.00036 19.9 0.0 2.2 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Rieske_2 PF13806.6 PSC68087.1 - 7.8e-05 22.6 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain zf-C3HC4_3 PF13920.6 PSC68087.1 - 0.00015 21.6 5.8 0.00015 21.6 5.8 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Ribosomal_L7Ae PF01248.26 PSC68087.1 - 0.00032 20.4 0.1 0.00078 19.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family zf-C2H2_jaz PF12171.8 PSC68087.1 - 0.06 13.6 0.8 0.14 12.4 0.8 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Dev_Cell_Death PF10539.9 PSC68087.1 - 0.086 12.7 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Development and cell death domain Prok-RING_4 PF14447.6 PSC68087.1 - 0.8 9.6 7.7 2.6 8.0 7.7 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Rieske PF00355.26 PSC68088.1 - 5.1e-10 39.2 0.0 1.5e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Abhydrolase_1 PF00561.20 PSC68088.1 - 2.1e-09 37.4 0.1 1.4e-07 31.5 0.1 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC68088.1 - 3.4e-05 23.2 0.0 0.00036 19.9 0.0 2.2 1 1 0 2 2 2 1 Serine aminopeptidase, S33 Rieske_2 PF13806.6 PSC68088.1 - 7.9e-05 22.5 0.0 0.00016 21.5 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain zf-C3HC4_3 PF13920.6 PSC68088.1 - 0.00015 21.5 5.8 0.00015 21.5 5.8 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Ribosomal_L7Ae PF01248.26 PSC68088.1 - 0.00033 20.3 0.1 0.0008 19.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family zf-C2H2_jaz PF12171.8 PSC68088.1 - 0.061 13.6 0.8 0.15 12.4 0.8 1.7 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Dev_Cell_Death PF10539.9 PSC68088.1 - 0.087 12.7 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Development and cell death domain Prok-RING_4 PF14447.6 PSC68088.1 - 0.82 9.6 7.7 2.7 7.9 7.7 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Inositol_P PF00459.25 PSC68089.1 - 2e-66 224.3 0.3 2.7e-66 223.9 0.3 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family DUF563 PF04577.14 PSC68089.1 - 1.2e-13 51.6 0.0 2.2e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF5056 PF16479.5 PSC68090.1 - 0.027 14.7 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5056) dCMP_cyt_deam_1 PF00383.23 PSC68090.1 - 0.37 10.7 2.6 7.6 6.5 0.5 2.1 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region DUF5056 PF16479.5 PSC68091.1 - 0.027 14.7 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5056) dCMP_cyt_deam_1 PF00383.23 PSC68091.1 - 0.37 10.7 2.6 7.6 6.5 0.5 2.1 2 0 0 2 2 2 0 Cytidine and deoxycytidylate deaminase zinc-binding region zf-CCCH PF00642.24 PSC68092.1 - 2e-13 49.9 11.5 1.2e-10 41.0 2.4 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) U-box PF04564.15 PSC68092.1 - 7.9e-13 48.4 0.0 1.4e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-CCCH_4 PF18044.1 PSC68092.1 - 7.3e-06 25.7 4.9 7.3e-06 25.7 4.9 2.9 3 0 0 3 3 3 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PSC68092.1 - 8.4e-06 25.7 19.9 2.1e-05 24.4 8.0 3.1 2 1 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 PSC68092.1 - 9.9e-05 22.7 16.6 0.00034 21.0 3.7 2.4 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 PSC68092.1 - 0.0002 21.6 1.8 0.016 15.4 0.4 2.5 2 0 0 2 2 2 1 Zinc-finger containing family zf-Nse PF11789.8 PSC68092.1 - 0.00073 19.3 0.0 0.0018 18.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Torus PF16131.5 PSC68092.1 - 0.00081 20.1 2.1 0.46 11.2 0.1 2.4 2 0 0 2 2 2 2 Torus domain zf-NOSIP PF15906.5 PSC68092.1 - 0.036 14.2 0.0 0.07 13.3 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Trypsin PF00089.26 PSC68093.1 - 4.5e-26 92.0 0.0 9.9e-26 90.9 0.0 1.6 1 0 0 1 1 1 1 Trypsin Gal_Lectin PF02140.18 PSC68093.1 - 4.6e-15 55.8 1.8 2.7e-08 34.1 0.0 6.6 5 3 1 6 6 6 2 Galactose binding lectin domain LPMO_10 PF03067.15 PSC68094.1 - 3.1e-13 50.8 0.3 3.7e-13 50.6 0.3 1.3 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_14 PF01607.24 PSC68094.1 - 1.1e-06 28.6 7.2 1.1e-06 28.6 7.2 2.4 3 0 0 3 3 3 1 Chitin binding Peritrophin-A domain SIP1 PF04938.12 PSC68095.1 - 5.9e-36 124.2 0.0 6.9e-36 124.0 0.0 1.1 1 0 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) DUF1633 PF07794.11 PSC68095.1 - 0.038 12.2 2.0 0.044 12.0 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1633) Lipase_GDSL_2 PF13472.6 PSC68096.1 - 0.0057 17.1 0.1 0.018 15.5 0.1 1.8 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family HD_5 PF13487.6 PSC68096.1 - 0.025 14.8 0.1 0.072 13.4 0.0 1.7 2 0 0 2 2 2 0 HD domain CRT-like PF08627.10 PSC68097.1 - 2.8e-38 131.7 4.5 3.9e-38 131.2 4.5 1.2 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like Lipase_GDSL_2 PF13472.6 PSC68097.1 - 7.7e-07 29.7 0.2 1.6e-06 28.7 0.2 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Sigma_M_inh PF17453.2 PSC68097.1 - 0.28 11.7 1.1 0.97 9.9 1.1 1.9 1 0 0 1 1 1 0 Sigma-M inhibitor PUNUT PF16913.5 PSC68097.1 - 0.64 9.2 11.2 0.021 14.0 4.5 1.8 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport Sugar_tr PF00083.24 PSC68098.1 - 1.5e-28 99.9 9.6 1.5e-28 99.9 9.6 1.6 2 0 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 PSC68098.1 - 6e-11 41.9 39.3 6e-11 41.9 39.3 3.1 2 1 1 3 3 3 2 Major Facilitator Superfamily MFS_2 PF13347.6 PSC68098.1 - 0.0011 17.7 0.6 0.0011 17.7 0.6 3.4 4 1 0 4 4 4 2 MFS/sugar transport protein DUF3584 PF12128.8 PSC68098.1 - 0.37 8.3 10.1 0.5 7.8 10.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) MIP-T3_C PF17749.1 PSC68098.1 - 0.54 10.2 4.1 0.18 11.7 0.3 2.0 2 1 0 2 2 2 0 Microtubule-binding protein MIP-T3 C-terminal region Abhydrolase_1 PF00561.20 PSC68099.1 - 1e-08 35.1 0.0 2.5e-07 30.6 0.0 2.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC68099.1 - 3.4e-08 33.0 0.0 2.1e-07 30.5 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 DAGAT PF03982.13 PSC68099.1 - 1.7e-07 30.4 0.0 2.7e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Abhydrolase_6 PF12697.7 PSC68099.1 - 2e-06 28.6 10.1 2e-06 28.6 10.1 3.2 2 1 1 3 3 3 1 Alpha/beta hydrolase family Acyltransferase PF01553.21 PSC68099.1 - 3.6e-05 23.4 0.0 0.043 13.4 0.0 2.4 2 0 0 2 2 2 2 Acyltransferase Esterase PF00756.20 PSC68099.1 - 0.0084 15.8 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Putative esterase BAAT_C PF08840.11 PSC68099.1 - 0.091 12.7 0.0 0.55 10.1 0.0 1.9 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Sulfotransfer_3 PF13469.6 PSC68100.1 - 3.4e-09 37.4 2.8 2e-07 31.6 0.2 3.0 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PSC68100.1 - 4.7e-07 29.5 0.1 8.3e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase domain DUF3525 PF12039.8 PSC68100.1 - 0.008 15.0 0.0 0.012 14.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3525) Ku PF02735.16 PSC68101.1 - 6.7e-28 97.8 0.0 1e-27 97.2 0.0 1.3 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain rve PF00665.26 PSC68101.1 - 1.4e-18 67.2 0.0 4.2e-18 65.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Ku_PK_bind PF08785.11 PSC68101.1 - 4.2e-11 43.0 0.0 8e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Ku C terminal domain like Ku_C PF03730.14 PSC68101.1 - 7.9e-05 23.3 0.1 0.00037 21.1 0.1 2.2 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm rve_3 PF13683.6 PSC68101.1 - 0.014 15.2 0.0 0.039 13.7 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain VWA_2 PF13519.6 PSC68101.1 - 0.021 15.5 0.0 0.34 11.6 0.0 2.8 1 1 1 2 2 2 0 von Willebrand factor type A domain McyA_C PF12593.8 PSC68102.1 - 0.053 13.3 2.9 1.3 8.8 0.6 3.3 3 0 0 3 3 3 0 Microcystin synthetase C terminal SBP PF03110.14 PSC68104.1 - 4.9e-39 132.5 17.6 3.9e-22 78.3 2.3 3.4 4 0 0 4 4 4 2 SBP domain Jiv90 PF14901.6 PSC68104.1 - 3 8.1 6.8 16 5.7 0.2 2.6 2 0 0 2 2 2 0 Cleavage inducing molecular chaperone Chlorophyllase2 PF12740.7 PSC68105.1 - 2.3e-18 66.0 0.0 3.3e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Chlorophyllase PF07224.11 PSC68105.1 - 3.8e-14 52.4 0.0 6e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Chlorophyllase Abhydrolase_1 PF00561.20 PSC68105.1 - 0.0019 17.9 0.0 0.015 14.9 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC68105.1 - 0.0096 15.2 0.0 0.081 12.2 0.0 2.3 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 PSC68105.1 - 0.012 15.4 0.0 0.11 12.4 0.0 2.4 3 0 0 3 3 3 0 alpha/beta hydrolase fold DUF2974 PF11187.8 PSC68105.1 - 0.032 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.7 PSC68105.1 - 0.06 13.1 0.0 0.21 11.4 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family Sulfotransfer_3 PF13469.6 PSC68106.1 - 1.7e-08 35.1 0.3 4.5e-07 30.5 0.0 2.8 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PSC68106.1 - 1.9e-05 24.3 0.0 5.5e-05 22.8 0.0 1.8 2 1 0 2 2 2 1 Sulfotransferase domain Gpi16 PF04113.14 PSC68107.1 - 2.8e-92 310.0 0.0 4.2e-92 309.4 0.0 1.2 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Fer2 PF00111.27 PSC68108.1 - 6.6e-08 32.4 0.5 1.3e-07 31.5 0.5 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DUF2722 PF10846.8 PSC68108.1 - 0.0029 16.6 5.5 0.0029 16.6 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Fer2_4 PF13510.6 PSC68108.1 - 0.016 15.3 1.5 0.11 12.5 1.5 2.2 1 1 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Spt20 PF12090.8 PSC68108.1 - 0.08 12.5 15.8 0.097 12.3 15.8 1.1 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 PSC68108.1 - 0.2 11.6 15.0 0.24 11.4 15.0 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med3 PF11593.8 PSC68108.1 - 0.26 10.5 19.5 0.29 10.3 19.5 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal UPF0560 PF10577.9 PSC68108.1 - 1.7 7.0 6.9 2.1 6.8 6.9 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 RHD3 PF05879.12 PSC68109.1 - 1.2e-185 618.8 0.0 1.6e-185 618.5 0.0 1.0 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) GYF PF02213.16 PSC68109.1 - 3.4e-09 36.2 0.0 7.1e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 GYF domain MMR_HSR1 PF01926.23 PSC68109.1 - 6.9e-05 22.9 0.0 0.00023 21.2 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PSC68109.1 - 0.00082 19.5 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 Dynamin family GBP PF02263.19 PSC68109.1 - 0.0021 17.4 0.0 0.0035 16.6 0.0 1.2 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain ABC_tran PF00005.27 PSC68109.1 - 0.013 16.0 0.0 0.036 14.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_28 PF13521.6 PSC68109.1 - 0.061 13.6 0.0 0.18 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 PSC68109.1 - 0.23 11.5 0.0 0.47 10.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PSC68109.1 - 0.28 11.6 0.0 0.28 11.6 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain Kinesin PF00225.23 PSC68111.1 - 2.9e-97 325.6 0.3 6.7e-97 324.4 0.0 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PSC68111.1 - 1.2e-50 171.3 0.0 4.1e-50 169.6 0.0 2.0 1 0 0 1 1 1 1 Microtubule binding Tup_N PF08581.10 PSC68111.1 - 0.0053 17.0 1.9 0.0053 17.0 1.9 4.7 5 0 0 5 5 5 1 Tup N-terminal Spc7 PF08317.11 PSC68111.1 - 1 8.1 68.1 0.041 12.7 13.7 4.5 1 1 4 5 5 5 0 Spc7 kinetochore protein Erythro-docking PF09277.11 PSC68111.1 - 1.1 9.2 9.3 7 6.6 0.2 4.7 4 0 0 4 4 4 0 Erythronolide synthase, docking YabA PF06156.13 PSC68111.1 - 2.8 8.6 32.6 10 6.8 0.0 7.0 6 2 1 7 7 7 0 Initiation control protein YabA Pro_CA PF00484.19 PSC68112.1 - 1.8e-13 51.1 0.2 3.3e-12 47.0 0.2 2.0 1 1 1 2 2 2 1 Carbonic anhydrase ubiquitin PF00240.23 PSC68113.1 - 7.9e-35 118.4 0.4 1.1e-34 118.0 0.4 1.2 1 0 0 1 1 1 1 Ubiquitin family Ribosomal_L40e PF01020.17 PSC68113.1 - 1.6e-31 107.9 9.3 2.5e-31 107.3 9.3 1.3 1 0 0 1 1 1 1 Ribosomal L40e family Rad60-SLD PF11976.8 PSC68113.1 - 5.5e-17 61.4 0.5 9.5e-17 60.6 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PSC68113.1 - 1.5e-05 25.3 0.1 6.3e-05 23.3 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 PSC68113.1 - 0.0049 16.8 0.0 0.0071 16.3 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 PSC68113.1 - 0.0056 17.0 0.1 0.0093 16.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 PSC68113.1 - 0.0065 16.6 0.1 0.013 15.6 0.1 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like zf-C4pol PF14260.6 PSC68113.1 - 0.009 16.5 0.7 0.015 15.7 0.7 1.4 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Ubiquitin_4 PF18036.1 PSC68113.1 - 0.014 15.4 1.1 2.8 8.0 0.2 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 PSC68113.1 - 0.017 15.7 0.1 0.019 15.5 0.1 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Metallophos PF00149.28 PSC68114.1 - 5.1e-09 36.9 0.1 9.4e-09 36.1 0.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Tim17 PF02466.19 PSC68115.1 - 9.5e-07 29.2 1.4 9.5e-07 29.2 1.4 2.0 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family MarC PF01914.17 PSC68115.1 - 0.074 12.4 0.0 0.15 11.4 0.0 1.5 1 0 0 1 1 1 0 MarC family integral membrane protein Pkinase PF00069.25 PSC68117.1 - 4.5e-49 167.2 0.0 1.2e-48 165.8 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC68117.1 - 1.4e-47 162.2 0.0 5.4e-47 160.3 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase ResB PF05140.14 PSC68118.1 - 1e-90 304.9 0.0 1.4e-71 241.7 0.0 2.0 1 1 1 2 2 2 2 ResB-like family AAA PF00004.29 PSC68119.1 - 3.7e-05 24.2 0.0 8.8e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PSC68119.1 - 8e-05 23.1 0.3 0.00071 20.0 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.15 PSC68119.1 - 0.00012 22.1 0.1 0.15 12.0 0.0 2.6 2 0 0 2 2 2 2 NTPase AAA_30 PF13604.6 PSC68119.1 - 0.00027 20.7 0.0 0.00081 19.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain SRP54 PF00448.22 PSC68119.1 - 0.0018 17.9 0.0 0.0051 16.5 0.0 1.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_5 PF07728.14 PSC68119.1 - 0.0032 17.5 0.0 0.0063 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PSC68119.1 - 0.0086 16.4 0.0 0.033 14.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PSC68119.1 - 0.015 15.8 0.0 0.029 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 PSC68119.1 - 0.018 14.8 0.0 0.028 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PSC68119.1 - 0.021 14.3 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 PSC68119.1 - 0.022 14.9 0.0 0.052 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 PSC68119.1 - 0.025 14.6 0.0 0.046 13.8 0.0 1.5 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.6 PSC68119.1 - 0.036 14.4 0.0 0.11 12.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_31 PF13614.6 PSC68119.1 - 0.04 13.8 0.0 0.07 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 PSC68119.1 - 0.049 13.4 0.0 0.11 12.3 0.0 1.4 1 1 1 2 2 2 0 AAA domain KTI12 PF08433.10 PSC68119.1 - 0.072 12.5 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 PSC68119.1 - 0.083 13.3 0.0 0.2 12.1 0.0 1.6 2 0 0 2 2 1 0 RNA helicase Sigma54_activat PF00158.26 PSC68119.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 PSC68119.1 - 0.11 12.6 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase RuvB_N PF05496.12 PSC68119.1 - 0.12 12.1 0.0 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 PSC68119.1 - 0.13 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea TrwB_AAD_bind PF10412.9 PSC68119.1 - 0.13 11.1 0.0 0.29 10.0 0.0 1.5 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain ArsA_ATPase PF02374.15 PSC68119.1 - 0.14 11.3 0.0 0.28 10.3 0.0 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase AAA_3 PF07726.11 PSC68119.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.18 PSC68119.1 - 0.18 11.5 0.0 0.34 10.6 0.0 1.4 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase RsgA_GTPase PF03193.16 PSC68119.1 - 0.21 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase ATP_bind_1 PF03029.17 PSC68119.1 - 0.24 11.2 0.0 0.36 10.6 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Methyltransf_11 PF08241.12 PSC68120.1 - 1.3e-19 70.6 0.0 3.3e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC68120.1 - 7.8e-17 61.8 0.0 1.8e-16 60.6 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC68120.1 - 6.4e-14 52.5 0.0 2.6e-13 50.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC68120.1 - 1.1e-08 35.0 0.0 2.1e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC68120.1 - 3.5e-08 33.5 0.0 5.7e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PSC68120.1 - 4.8e-08 32.7 0.0 8.5e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 PSC68120.1 - 1.3e-07 31.2 0.0 2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_2 PF00891.18 PSC68120.1 - 6.3e-07 28.9 0.0 9.5e-07 28.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_24 PF13578.6 PSC68120.1 - 1.1e-05 26.4 0.0 2.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 PSC68120.1 - 0.022 14.3 0.0 0.032 13.7 0.0 1.2 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Rsm22 PF09243.10 PSC68120.1 - 0.035 13.4 0.0 0.063 12.6 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_29 PF03141.16 PSC68120.1 - 0.13 10.8 0.0 0.47 8.9 0.0 1.8 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase AA_kinase PF00696.28 PSC68120.1 - 0.18 11.3 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 Amino acid kinase family SMC_N PF02463.19 PSC68121.1 - 7.6e-26 90.9 0.0 1.2e-25 90.3 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 PSC68121.1 - 2.2e-15 57.7 0.0 2.2e-15 57.7 0.0 3.7 3 1 0 3 3 3 1 AAA domain AAA_15 PF13175.6 PSC68121.1 - 2.4e-09 37.4 2.5 5.9e-09 36.1 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 PSC68121.1 - 2.3e-05 24.0 0.0 4.7e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 PSC68121.1 - 0.0013 18.6 0.0 0.0024 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system MukB PF04310.12 PSC68121.1 - 0.0022 17.8 1.8 0.0065 16.3 0.0 2.6 3 0 0 3 3 3 1 MukB N-terminal RE_TdeIII PF09520.10 PSC68121.1 - 0.0095 15.6 0.2 0.027 14.1 0.2 1.7 1 0 0 1 1 1 1 Type II restriction endonuclease, TdeIII RsgA_GTPase PF03193.16 PSC68121.1 - 0.27 11.1 1.5 0.4 10.6 0.1 2.0 2 0 0 2 2 2 0 RsgA GTPase Bap31_Bap29_C PF18035.1 PSC68121.1 - 3.5 7.7 8.2 0.34 11.0 0.7 3.0 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain FIST PF08495.10 PSC68122.1 - 0.027 14.5 0.1 0.052 13.6 0.1 1.5 1 1 0 1 1 1 0 FIST N domain Pkinase_Tyr PF07714.17 PSC68123.1 - 6.6e-05 22.3 0.0 0.00011 21.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC68123.1 - 0.0019 17.6 0.0 0.0029 17.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Rad51 PF08423.11 PSC68124.1 - 1.4e-114 381.6 0.3 2.2e-114 381.0 0.3 1.3 1 0 0 1 1 1 1 Rad51 cobW PF02492.19 PSC68124.1 - 4.7e-50 169.6 0.1 1.2e-49 168.3 0.1 1.7 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 PSC68124.1 - 2.3e-21 75.5 0.1 1.7e-20 72.7 0.0 2.6 3 0 0 3 3 3 1 Cobalamin synthesis protein cobW C-terminal domain WW PF00397.26 PSC68124.1 - 8.3e-11 41.8 1.3 1.5e-10 40.9 1.3 1.5 1 0 0 1 1 1 1 WW domain AAA_25 PF13481.6 PSC68124.1 - 4.8e-09 36.1 0.1 7.7e-08 32.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain RecA PF00154.21 PSC68124.1 - 5e-08 32.7 0.6 8.6e-08 32.0 0.2 1.5 2 0 0 2 2 1 1 recA bacterial DNA recombination protein AAA_24 PF13479.6 PSC68124.1 - 2.7e-06 27.2 0.0 0.00038 20.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 PSC68124.1 - 2.4e-05 23.8 0.1 0.00075 18.9 0.0 2.5 2 0 0 2 2 2 1 KaiC AAA_22 PF13401.6 PSC68124.1 - 7.3e-05 23.1 1.9 0.12 12.6 0.2 3.1 2 2 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 PSC68124.1 - 0.00021 21.3 0.0 0.49 10.3 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase HHH_5 PF14520.6 PSC68124.1 - 0.0004 20.9 5.7 0.00095 19.7 2.6 3.0 3 0 0 3 3 3 1 Helix-hairpin-helix domain AAA PF00004.29 PSC68124.1 - 0.00057 20.3 0.0 0.19 12.2 0.0 3.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PSC68124.1 - 0.0013 19.1 1.5 0.028 14.8 0.0 3.1 3 1 0 3 3 3 1 AAA ATPase domain ATPase_2 PF01637.18 PSC68124.1 - 0.008 16.1 0.2 0.61 10.0 0.0 2.4 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea TsaE PF02367.17 PSC68124.1 - 0.0091 16.0 0.2 0.11 12.6 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 PSC68124.1 - 0.011 16.3 0.0 0.7 10.4 0.0 2.6 2 1 0 2 2 2 0 ABC transporter GTP_EFTU PF00009.27 PSC68124.1 - 0.024 14.2 0.0 1.9 8.0 0.0 2.4 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_33 PF13671.6 PSC68124.1 - 0.035 14.3 0.1 0.39 10.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 PSC68124.1 - 0.04 13.0 0.0 0.094 11.8 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Viral_helicase1 PF01443.18 PSC68124.1 - 0.064 13.0 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TniB PF05621.11 PSC68124.1 - 0.07 12.5 0.1 5.6 6.3 0.0 2.8 2 1 0 2 2 2 0 Bacterial TniB protein AAA_14 PF13173.6 PSC68124.1 - 0.089 12.8 0.1 0.51 10.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain CCDC53 PF10152.9 PSC68124.1 - 0.12 12.7 0.1 0.59 10.5 0.1 2.2 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex ATP-synt_ab PF00006.25 PSC68124.1 - 0.15 11.7 0.3 1.7 8.3 0.0 2.5 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 PSC68124.1 - 0.15 12.2 0.0 0.94 9.6 0.1 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase Arf PF00025.21 PSC68124.1 - 0.19 11.2 1.3 2.1 7.8 0.1 2.7 3 0 0 3 3 3 0 ADP-ribosylation factor family dNK PF01712.19 PSC68124.1 - 0.24 11.2 0.1 0.48 10.2 0.1 1.4 1 0 0 1 1 1 0 Deoxynucleoside kinase Ferritin PF00210.24 PSC68126.1 - 3.1e-05 24.0 0.0 4.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Ferritin-like domain DUF11 PF01345.18 PSC68126.1 - 0.00012 22.4 47.7 0.0069 16.7 3.7 6.8 6 1 0 6 6 6 3 Domain of unknown function DUF11 Big_3_5 PF16640.5 PSC68126.1 - 0.0091 16.2 1.2 0.0091 16.2 1.2 8.7 4 3 3 9 9 9 4 Bacterial Ig-like domain (group 3) PPR_2 PF13041.6 PSC68127.1 - 1.5e-20 73.1 0.1 2e-07 31.1 0.0 6.0 6 1 1 7 7 7 4 PPR repeat family PPR PF01535.20 PSC68127.1 - 6.7e-17 60.5 6.4 0.0024 18.0 0.0 6.6 7 0 0 7 7 7 4 PPR repeat PPR_3 PF13812.6 PSC68127.1 - 1.9e-10 40.7 0.0 1e-05 25.5 0.0 3.9 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.7 PSC68127.1 - 1.9e-09 37.0 0.2 0.00019 21.1 0.0 5.2 5 0 0 5 5 5 1 PPR repeat PPR_long PF17177.4 PSC68127.1 - 4.1e-05 23.0 0.1 0.00031 20.2 0.0 2.5 3 1 0 3 3 3 1 Pentacotripeptide-repeat region of PRORP Foie-gras_1 PF11817.8 PSC68127.1 - 0.018 14.7 0.3 0.045 13.3 0.0 1.7 2 0 0 2 2 2 0 Foie gras liver health family 1 Ribosomal_60s PF00428.19 PSC68127.1 - 0.84 10.3 10.1 13 6.5 11.2 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein CW_binding_2 PF04122.12 PSC68127.1 - 2.3 8.9 5.6 4.7 7.9 5.6 1.5 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 Pentapeptide PF00805.22 PSC68128.1 - 1.8e-20 72.2 28.5 9.2e-10 38.0 6.0 3.2 1 1 3 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 PSC68128.1 - 4.1e-06 26.9 0.0 7.6e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 PSC68128.1 - 3.4e-05 23.9 0.0 0.0082 16.3 0.0 2.9 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) ABC_tran_Xtn PF12848.7 PSC68128.1 - 0.09 12.8 1.0 0.25 11.4 1.0 1.7 1 0 0 1 1 1 0 ABC transporter rve PF00665.26 PSC68129.1 - 1e-18 67.6 0.0 3e-18 66.1 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC68129.1 - 0.01 15.6 0.0 0.029 14.2 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Staygreen PF12638.7 PSC68130.1 - 4.1e-32 111.0 0.0 9.4e-32 109.8 0.0 1.6 1 1 0 1 1 1 1 Staygreen protein Peptidase_M24 PF00557.24 PSC68131.1 - 2.9e-37 128.4 0.0 3.7e-37 128.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 CDT1_C PF16679.5 PSC68131.1 - 0.0061 17.0 0.0 0.018 15.5 0.0 1.8 1 0 0 1 1 1 1 DNA replication factor Cdt1 C-terminal domain Gal_Lectin PF02140.18 PSC68132.1 - 1e-09 38.7 0.1 1.7e-09 38.0 0.1 1.3 1 0 0 1 1 1 1 Galactose binding lectin domain Pectate_lyase_3 PF12708.7 PSC68132.1 - 1.5e-07 31.5 0.9 1e-06 28.8 0.0 2.3 2 1 0 2 2 2 1 Pectate lyase superfamily protein PAP1 PF08601.10 PSC68133.1 - 0.026 14.3 9.9 0.028 14.2 9.9 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 FAM60A PF15396.6 PSC68133.1 - 0.2 11.6 18.1 0.21 11.6 18.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Rrn6 PF10214.9 PSC68133.1 - 0.3 9.5 14.3 0.33 9.4 14.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SRP-alpha_N PF04086.13 PSC68133.1 - 0.42 10.5 25.9 0.53 10.2 25.9 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal LRIF1 PF15741.5 PSC68133.1 - 0.68 8.4 18.9 0.71 8.3 18.9 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Connexin PF00029.19 PSC68133.1 - 1 9.0 11.9 1 9.0 11.9 1.3 1 0 0 1 1 1 0 Connexin DUF4603 PF15376.6 PSC68133.1 - 1.1 6.6 25.6 1.2 6.4 25.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) CKAP2_C PF15297.6 PSC68133.1 - 1.2 8.2 16.4 1.6 7.8 16.4 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus NARP1 PF12569.8 PSC68133.1 - 1.7 7.4 21.8 2 7.3 21.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 EIIBC-GUT_N PF03612.14 PSC68133.1 - 1.8 8.3 6.7 2.1 8.0 6.7 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Macoilin PF09726.9 PSC68133.1 - 1.9 6.9 18.7 1.9 6.9 18.7 1.0 1 0 0 1 1 1 0 Macoilin family MCM_bind PF09739.9 PSC68133.1 - 2.1 6.7 16.0 2.4 6.5 16.0 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF3807 PF12720.7 PSC68133.1 - 2.1 8.6 27.2 2.5 8.3 27.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) GREB1 PF15782.5 PSC68133.1 - 2.8 4.9 12.7 2.9 4.9 12.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Chorion_2 PF03964.15 PSC68133.1 - 2.9 8.8 16.2 1.6 9.6 14.4 1.6 1 1 1 2 2 2 0 Chorion family 2 LAP1C PF05609.12 PSC68133.1 - 3.6 6.6 17.2 3.6 6.6 17.2 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Peptidase_U57 PF05582.12 PSC68133.1 - 3.6 6.8 10.4 4.7 6.4 10.4 1.1 1 0 0 1 1 1 0 YabG peptidase U57 DUF2828 PF11443.8 PSC68133.1 - 3.8 5.5 13.4 4.1 5.4 13.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) PPL5 PF18168.1 PSC68133.1 - 5.3 6.3 13.9 6.2 6.0 13.9 1.3 1 0 0 1 1 1 0 Prim-pol family 5 RR_TM4-6 PF06459.12 PSC68133.1 - 5.7 6.7 19.6 6.9 6.4 19.6 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Miga PF10265.9 PSC68133.1 - 5.8 5.8 11.1 6.3 5.7 11.1 1.1 1 0 0 1 1 1 0 Mitoguardin Sec62 PF03839.16 PSC68133.1 - 8 5.9 16.1 8.2 5.9 16.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 SLC12 PF03522.15 PSC68133.1 - 8.6 5.3 14.0 9.1 5.2 14.0 1.1 1 0 0 1 1 1 0 Solute carrier family 12 NAD_binding_1 PF00175.21 PSC68134.1 - 7.4e-24 84.5 0.0 1.4e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 PSC68134.1 - 0.019 15.3 0.0 0.037 14.4 0.0 1.4 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Pkinase PF00069.25 PSC68135.1 - 1.7e-24 86.6 0.0 3.4e-16 59.4 0.0 2.0 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC68135.1 - 1.3e-21 77.1 0.0 6.4e-21 74.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PRIMA1 PF16101.5 PSC68135.1 - 1.1 9.3 6.9 1.8 8.6 6.9 1.3 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 MCR_C PF04609.12 PSC68136.1 - 0.016 14.3 0.1 0.023 13.8 0.1 1.2 1 0 0 1 1 1 0 Methyl-coenzyme M reductase operon protein C F-box PF00646.33 PSC68137.1 - 2.1e-08 33.8 0.2 0.00036 20.3 0.0 2.8 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 PSC68137.1 - 0.00019 21.2 0.4 0.85 9.6 0.0 3.2 3 0 0 3 3 3 2 F-box-like LRR_4 PF12799.7 PSC68137.1 - 0.011 16.1 4.2 0.67 10.5 0.0 4.8 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC68137.1 - 0.022 14.5 5.5 0.026 14.3 0.2 3.6 4 0 0 4 4 4 0 Leucine rich repeat RRM_1 PF00076.22 PSC68138.1 - 3.3e-29 100.5 0.0 5e-10 39.1 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U-box PF04564.15 PSC68138.1 - 4.1e-13 49.3 0.1 7.7e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 U-box domain Ysc84 PF04366.12 PSC68138.1 - 5.5e-10 39.1 0.0 7.8e-09 35.4 0.0 2.9 1 1 0 1 1 1 1 Las17-binding protein actin regulator zf-NOSIP PF15906.5 PSC68138.1 - 0.061 13.5 0.0 0.16 12.1 0.0 1.7 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein DUF4523 PF15023.6 PSC68138.1 - 0.062 13.1 0.0 2.7 7.8 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4523) Ank_2 PF12796.7 PSC68138.1 - 0.077 13.6 0.1 0.3 11.7 0.1 2.0 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) TRAM_LAG1_CLN8 PF03798.16 PSC68140.1 - 1.8e-15 57.2 10.7 2.4e-15 56.8 10.7 1.2 1 0 0 1 1 1 1 TLC domain TRAM_LAG1_CLN8 PF03798.16 PSC68141.1 - 1.8e-15 57.2 10.7 2.4e-15 56.8 10.7 1.2 1 0 0 1 1 1 1 TLC domain Glyco_hydro_18 PF00704.28 PSC68143.1 - 2.3e-14 53.9 0.0 3.9e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Reprolysin_5 PF13688.6 PSC68143.1 - 2.5e-05 24.5 2.2 2.9e-05 24.3 0.1 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12 PPC PF04151.15 PSC68143.1 - 0.0016 19.5 0.4 0.0074 17.4 0.4 2.3 1 1 0 1 1 1 1 Bacterial pre-peptidase C-terminal domain Reprolysin_3 PF13582.6 PSC68143.1 - 0.013 16.0 0.1 0.048 14.2 0.1 1.9 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 PSC68143.1 - 0.02 13.8 4.0 0.034 13.1 4.0 1.2 1 0 0 1 1 1 0 Peptidase M66 CBM_14 PF01607.24 PSC68143.1 - 0.023 14.9 13.1 0.051 13.7 13.1 1.6 1 0 0 1 1 1 0 Chitin binding Peritrophin-A domain HrpB7 PF09486.10 PSC68143.1 - 0.085 13.2 1.1 0.15 12.5 1.1 1.3 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Reprolysin_2 PF13574.6 PSC68143.1 - 0.15 12.0 0.7 0.35 10.8 0.7 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Ndc1_Nup PF09531.10 PSC68144.1 - 1.9e-07 30.2 0.1 0.00051 18.9 0.0 2.7 2 1 0 3 3 3 2 Nucleoporin protein Ndc1-Nup Herpes_TAF50 PF03326.13 PSC68144.1 - 0.33 9.6 5.1 0.51 8.9 5.1 1.2 1 0 0 1 1 1 0 Herpesvirus transcription activation factor (transactivator) Ndc1_Nup PF09531.10 PSC68145.1 - 4.9e-08 32.1 0.0 0.00025 19.9 0.0 2.6 1 1 0 2 2 2 2 Nucleoporin protein Ndc1-Nup HMG_box PF00505.19 PSC68146.1 - 3.8e-20 72.1 0.9 6.6e-20 71.3 0.9 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PSC68146.1 - 7.9e-12 45.6 0.4 1.2e-11 45.0 0.4 1.3 1 0 0 1 1 1 1 HMG-box domain DUF4417 PF14386.6 PSC68146.1 - 0.0098 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4417) PAD_porph PF04371.15 PSC68147.1 - 5.2e-126 420.2 0.0 6e-126 420.1 0.0 1.0 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase Amidinotransf PF02274.17 PSC68147.1 - 0.081 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Amidinotransferase NAD_binding_10 PF13460.6 PSC68148.1 - 6.7e-14 52.2 0.9 1.3e-13 51.3 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 PSC68148.1 - 8.9e-07 28.7 0.0 1.5e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 PSC68148.1 - 0.00016 21.2 0.0 0.00034 20.1 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PSC68148.1 - 0.011 14.8 0.0 0.059 12.4 0.0 2.0 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Na_H_Exchanger PF00999.21 PSC68149.1 - 6.4e-48 163.5 38.5 6.4e-48 163.5 38.5 1.6 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family DUF1118 PF06549.12 PSC68149.1 - 3.7e-35 120.7 6.8 3.7e-35 120.7 6.8 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1118) B12D PF06522.11 PSC68150.1 - 8.9e-10 38.2 0.0 1.3e-09 37.7 0.0 1.3 1 1 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit CN_hydrolase PF00795.22 PSC68151.1 - 8.3e-52 176.1 0.0 1.4e-51 175.4 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase PCRF PF03462.18 PSC68151.1 - 4.1e-49 167.1 0.7 8.2e-49 166.1 0.7 1.5 1 0 0 1 1 1 1 PCRF domain PDZ_3 PF17815.1 PSC68151.1 - 8.2e-36 123.0 0.0 1.5e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 PDZ domain RF-1 PF00472.20 PSC68151.1 - 2.2e-34 117.9 0.1 5.8e-34 116.5 0.1 1.8 1 0 0 1 1 1 1 RF-1 domain Trypsin_2 PF13365.6 PSC68151.1 - 9.5e-18 65.5 1.2 3e-17 63.9 0.2 2.4 3 0 0 3 3 3 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 PSC68151.1 - 4e-09 36.7 0.2 4.2e-08 33.4 0.2 2.4 2 0 0 2 2 2 1 PDZ domain Trypsin PF00089.26 PSC68151.1 - 2.3e-08 34.1 0.1 3.9e-07 30.1 0.1 2.3 2 0 0 2 2 2 1 Trypsin PDZ_6 PF17820.1 PSC68151.1 - 6.2e-05 22.8 0.2 0.36 10.7 0.2 3.1 2 0 0 2 2 2 2 PDZ domain Peptidase_S46 PF10459.9 PSC68151.1 - 0.0011 17.7 0.1 0.0011 17.7 0.1 1.7 2 0 0 2 2 2 1 Peptidase S46 Peptidase_S7 PF00949.21 PSC68151.1 - 0.0056 16.5 0.1 0.012 15.4 0.1 1.5 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease HIG_1_N PF04588.13 PSC68152.1 - 2.9e-05 24.2 0.0 4.8e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DEAD PF00270.29 PSC68153.1 - 2.5e-42 144.6 0.5 4.6e-42 143.8 0.1 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC68153.1 - 1.7e-32 112.1 0.1 6.8e-32 110.1 0.0 2.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC68153.1 - 0.00012 22.2 0.0 0.00022 21.3 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 PSC68153.1 - 0.0038 17.6 0.4 0.02 15.2 0.2 2.1 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PSC68153.1 - 0.013 15.7 0.2 0.06 13.6 0.2 2.0 1 1 0 1 1 1 0 AAA domain CMS1 PF14617.6 PSC68153.1 - 0.016 14.5 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit AAA PF00004.29 PSC68153.1 - 0.035 14.5 0.0 0.16 12.4 0.0 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 PSC68153.1 - 0.041 13.6 0.1 0.086 12.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain Helicase_RecD PF05127.14 PSC68153.1 - 0.089 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Helicase RraA-like PF03737.15 PSC68154.1 - 5.6e-37 127.2 0.2 9.5e-37 126.5 0.2 1.3 1 0 0 1 1 1 1 Aldolase/RraA Metallophos PF00149.28 PSC68154.1 - 4.6e-35 122.0 0.3 7.4e-35 121.3 0.3 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 PSC68154.1 - 0.00043 20.7 0.2 0.0011 19.4 0.2 1.6 1 1 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Pep_deformylase PF01327.21 PSC68155.1 - 8.3e-44 149.0 0.0 1.2e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase PPR PF01535.20 PSC68157.1 - 6.3e-05 23.0 0.3 0.5 10.7 0.1 2.8 3 0 0 3 3 3 2 PPR repeat PPR_2 PF13041.6 PSC68157.1 - 8.9e-05 22.6 0.0 0.00044 20.4 0.0 2.0 2 0 0 2 2 2 1 PPR repeat family Pro_isomerase PF00160.21 PSC68158.1 - 2.9e-26 92.6 0.0 4.7e-26 92.0 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD C2 PF00168.30 PSC68159.1 - 0.064 13.6 0.0 1.6 9.1 0.0 2.9 4 0 0 4 4 4 0 C2 domain IRK_C PF17655.1 PSC68160.1 - 5.7e-53 179.1 0.0 1.6e-31 109.2 0.0 2.3 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 PSC68160.1 - 4.4e-16 59.0 13.7 3.8e-15 55.9 13.7 2.0 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Med3 PF11593.8 PSC68160.1 - 0.00046 19.5 21.4 0.00046 19.5 21.4 1.6 2 0 0 2 2 2 1 Mediator complex subunit 3 fungal Ion_trans_2 PF07885.16 PSC68160.1 - 0.015 15.2 13.5 0.027 14.4 13.5 1.4 1 0 0 1 1 1 0 Ion channel PHC2_SAM_assoc PF16616.5 PSC68160.1 - 0.69 10.7 7.0 2.2 9.1 7.0 1.8 1 0 0 1 1 1 0 Unstructured region on Polyhomeotic-like protein 1 and 2 TFIIA PF03153.13 PSC68160.1 - 2.9 7.8 18.2 4.9 7.0 18.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC2_membrane PF01061.24 PSC68161.1 - 5.9e-76 254.5 53.0 5.6e-45 153.3 26.8 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 PSC68161.1 - 2.4e-24 86.4 0.0 3.3e-19 69.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_assoc PF08370.11 PSC68161.1 - 1.3e-08 34.4 0.1 1.3e-08 34.4 0.1 3.8 3 0 0 3 3 2 1 Plant PDR ABC transporter associated AAA_21 PF13304.6 PSC68161.1 - 0.00071 19.5 0.0 1.3 8.7 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_trans_N PF14510.6 PSC68161.1 - 0.00073 20.1 0.0 0.0019 18.8 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_29 PF13555.6 PSC68161.1 - 0.0017 18.1 0.2 0.0043 16.8 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 PSC68161.1 - 0.0022 17.6 0.1 0.0054 16.3 0.1 1.6 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 PSC68161.1 - 0.0024 17.8 0.2 0.0063 16.4 0.1 1.7 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 PSC68161.1 - 0.032 14.6 0.1 0.079 13.3 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.6 PSC68161.1 - 0.034 14.3 0.0 0.077 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain ABC2_membrane_3 PF12698.7 PSC68161.1 - 2.2 7.3 47.6 0.01 15.0 13.8 3.0 3 0 0 3 3 3 0 ABC-2 family transporter protein Baculo_PEP_C PF04513.12 PSC68162.1 - 0.19 11.8 6.0 0.52 10.4 1.8 2.2 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Metal_resist PF13801.6 PSC68162.1 - 0.19 11.9 0.2 0.19 11.9 0.2 5.4 3 2 2 5 5 5 0 Heavy-metal resistance DLP_helical PF18709.1 PSC68162.1 - 1 8.5 9.5 6.3 5.9 9.5 2.0 1 1 0 1 1 1 0 Dynamin-like helical domain FapA PF03961.13 PSC68162.1 - 4.9 5.6 6.1 9.1 4.8 6.1 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Plasmid_RAQPRD PF09686.10 PSC68163.1 - 3.5 7.9 10.8 0.54 10.5 4.8 2.9 2 1 1 3 3 3 0 Plasmid protein of unknown function (Plasmid_RAQPRD) ENOD93 PF03386.14 PSC68165.1 - 3.4e-06 26.9 0.6 4e-06 26.6 0.6 1.1 1 0 0 1 1 1 1 Early nodulin 93 ENOD93 protein PC-Esterase PF13839.6 PSC68166.1 - 2.3e-05 24.3 2.5 0.1 12.3 1.3 2.8 2 1 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p HTH_33 PF13592.6 PSC68166.1 - 0.049 13.3 0.5 0.11 12.1 0.5 1.6 1 0 0 1 1 1 0 Winged helix-turn helix Period_C PF12114.8 PSC68166.1 - 8.7 5.9 5.8 13 5.3 5.8 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region GTP_EFTU PF00009.27 PSC68167.1 - 1.4e-68 230.3 0.0 2e-68 229.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 PSC68167.1 - 1.3e-44 150.8 0.1 2.4e-44 150.0 0.1 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 PSC68167.1 - 1.9e-31 108.0 0.0 3.6e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 PSC68167.1 - 6.1e-28 96.7 0.1 1.3e-27 95.6 0.1 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PSC68167.1 - 5.5e-18 65.1 0.6 2e-17 63.3 0.2 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RF3_C PF16658.5 PSC68167.1 - 2.5e-06 27.3 0.0 5.8e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 PSC68167.1 - 0.00028 20.9 0.0 0.00068 19.7 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 PSC68167.1 - 0.025 13.9 0.0 0.042 13.2 0.0 1.3 1 0 0 1 1 1 0 AIG1 family NAC PF01849.18 PSC68168.1 - 5.7e-19 67.9 0.0 5.7e-19 67.9 0.0 1.9 2 1 0 2 2 2 1 NAC domain DUF4033 PF13225.6 PSC68169.1 - 1.9e-35 120.7 0.2 3.1e-35 120.0 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) Nucleotid_trans PF03407.16 PSC68170.1 - 1.1e-45 156.3 0.2 3.6e-45 154.6 0.0 1.8 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase PHO4 PF01384.20 PSC68171.1 - 8e-115 383.5 20.0 1.4e-114 382.7 20.0 1.4 1 0 0 1 1 1 1 Phosphate transporter family DUF3042 PF11240.8 PSC68171.1 - 0.41 10.7 3.8 2.1 8.4 2.9 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3042) PHO4 PF01384.20 PSC68172.1 - 2.3e-114 382.0 21.8 4e-114 381.2 21.8 1.4 1 0 0 1 1 1 1 Phosphate transporter family DUF3042 PF11240.8 PSC68172.1 - 0.42 10.7 4.0 1.1 9.4 1.9 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3042) CwsA PF10814.8 PSC68172.1 - 1 9.5 6.3 0.41 10.8 2.1 2.4 2 0 0 2 2 2 0 Cell wall synthesis protein CwsA BORCS8 PF10167.9 PSC68173.1 - 0.00033 20.6 0.0 0.00049 20.0 0.0 1.3 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 8 DUF883 PF05957.13 PSC68173.1 - 0.033 14.8 2.8 0.72 10.5 0.4 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) Mucin PF01456.17 PSC68173.1 - 0.28 11.2 8.1 0.091 12.8 4.6 2.2 1 1 0 1 1 1 0 Mucin-like glycoprotein B56 PF01603.20 PSC68174.1 - 4.8e-180 599.0 9.0 5.7e-180 598.7 9.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) Adaptin_N PF01602.20 PSC68174.1 - 0.006 15.2 0.1 0.011 14.3 0.1 1.3 1 0 0 1 1 1 1 Adaptin N terminal region DUF1977 PF09320.11 PSC68174.1 - 0.22 11.8 2.7 0.48 10.7 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1977) Ephrin_rec_like PF07699.13 PSC68175.1 - 5e-25 87.0 66.9 7.4e-07 28.8 2.4 9.0 3 2 5 9 9 9 8 Putative ephrin-receptor like TNFR_c6 PF00020.18 PSC68175.1 - 0.025 15.0 51.8 0.25 11.8 0.1 10.6 4 2 5 10 10 10 0 TNFR/NGFR cysteine-rich region VSP PF03302.13 PSC68175.1 - 1.2 7.9 54.9 0.22 10.3 13.7 3.2 1 1 3 4 4 4 0 Giardia variant-specific surface protein DUF2318 PF10080.9 PSC68175.1 - 4.8 7.4 35.9 0.61 10.2 5.8 4.8 2 2 2 4 4 4 0 Predicted membrane protein (DUF2318) NTP_transferase PF00483.23 PSC68176.1 - 2.6e-15 56.7 0.0 4.9e-15 55.8 0.0 1.4 1 1 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 PSC68176.1 - 1.4e-12 48.3 3.2 1.4e-12 48.3 3.2 1.9 1 1 1 2 2 2 1 MobA-like NTP transferase domain Hexapep PF00132.24 PSC68176.1 - 1e-06 28.2 1.0 0.085 12.6 0.9 3.6 1 1 3 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 PSC68176.1 - 0.0084 15.1 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 L-fucokinase DUF4954 PF16314.5 PSC68176.1 - 0.041 12.0 0.0 0.095 10.8 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4954) Lipase_GDSL_2 PF13472.6 PSC68178.1 - 4e-19 69.7 1.9 1.5e-10 41.7 0.2 3.0 3 0 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family 4HBT PF03061.22 PSC68178.1 - 4.7e-08 33.3 0.1 1.2e-07 31.9 0.1 1.7 1 0 0 1 1 1 1 Thioesterase superfamily Mito_fiss_reg PF05308.11 PSC68178.1 - 0.27 11.3 0.3 4.8 7.2 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator Lipase_GDSL_2 PF13472.6 PSC68179.1 - 4e-19 69.7 1.9 1.6e-10 41.7 0.2 3.0 3 0 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family 4HBT PF03061.22 PSC68179.1 - 4.2e-08 33.4 0.1 1.2e-07 31.9 0.1 1.9 1 0 0 1 1 1 1 Thioesterase superfamily Mito_fiss_reg PF05308.11 PSC68179.1 - 0.27 11.3 0.3 4.8 7.2 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial fission regulator Snapin_Pallidin PF14712.6 PSC68180.1 - 0.004 17.6 0.9 0.004 17.6 0.9 3.1 3 0 0 3 3 3 1 Snapin/Pallidin MAP65_ASE1 PF03999.12 PSC68180.1 - 0.0079 15.0 0.4 0.0079 15.0 0.4 1.5 2 0 0 2 2 2 1 Microtubule associated protein (MAP65/ASE1 family) UPF0242 PF06785.11 PSC68180.1 - 0.1 12.7 0.3 0.1 12.7 0.3 2.5 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus CENP-F_leu_zip PF10473.9 PSC68180.1 - 0.2 11.7 15.6 0.24 11.4 0.5 2.7 2 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4407 PF14362.6 PSC68180.1 - 1.1 8.5 37.1 0.53 9.6 13.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF1822 PF08852.11 PSC68180.1 - 3.1 6.7 17.2 0.14 11.1 3.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1822) V_ATPase_I PF01496.19 PSC68180.1 - 3.3 5.5 3.6 14 3.4 0.9 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Tup_N PF08581.10 PSC68180.1 - 3.8 7.9 7.8 12 6.2 0.2 3.1 3 0 0 3 3 3 0 Tup N-terminal CCB1 PF12046.8 PSC68181.1 - 7.5e-43 145.8 0.1 1.5e-42 144.8 0.1 1.5 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B DUF3930 PF13067.6 PSC68181.1 - 0.033 14.4 0.0 0.062 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3930) Suf PF05843.14 PSC68181.1 - 0.1 12.6 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FKBP_C PF00254.28 PSC68182.1 - 2.8e-42 142.9 0.0 2.9e-14 53.2 0.0 4.3 4 0 0 4 4 4 4 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 PSC68182.1 - 7.3e-07 28.8 7.8 0.024 14.7 1.3 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 PSC68182.1 - 0.0018 18.0 6.9 0.29 11.0 0.7 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 PSC68182.1 - 0.0036 17.2 1.4 2 8.7 0.0 2.9 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 PSC68182.1 - 0.004 17.8 2.3 0.004 17.8 2.3 4.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 PSC68182.1 - 0.0071 16.6 4.6 0.025 14.9 2.5 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 PSC68182.1 - 0.12 12.1 2.7 0.32 10.7 0.4 2.6 2 0 0 2 2 2 0 TPR repeat TPR_8 PF13181.6 PSC68182.1 - 0.13 12.5 0.5 14 6.2 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 PSC68182.1 - 1.1 9.4 5.2 2.8 8.2 3.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 PSC68182.1 - 3.4 8.7 19.0 2.2 9.3 0.8 4.4 3 1 1 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 PSC68183.1 - 9.6e-44 149.7 0.0 1.4e-43 149.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.32 PSC68183.1 - 3.5e-32 107.5 2.0 1.1e-07 30.9 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PSC68183.1 - 9.9e-30 102.8 0.8 6.4e-15 55.4 0.2 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PSC68183.1 - 2.9e-28 95.4 1.1 5.9e-08 32.0 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 PSC68183.1 - 8.7e-21 72.4 3.2 1.7e-05 24.1 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 PSC68183.1 - 3.5e-20 71.6 2.8 1.4e-07 31.3 0.0 3.9 1 1 3 4 4 4 4 EF-hand domain pair Pkinase_Tyr PF07714.17 PSC68183.1 - 5.2e-13 48.9 0.0 8.7e-13 48.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_4 PF12763.7 PSC68183.1 - 4.3e-08 33.1 0.5 0.0002 21.3 0.0 2.5 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_11 PF08976.11 PSC68183.1 - 3.4e-07 31.1 0.0 0.047 14.6 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain EF-hand_9 PF14658.6 PSC68183.1 - 2.2e-05 24.7 0.0 0.089 13.1 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain Kinase-like PF14531.6 PSC68183.1 - 0.00047 19.6 0.0 0.00082 18.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like SPARC_Ca_bdg PF10591.9 PSC68183.1 - 0.00084 19.6 0.0 0.053 13.8 0.0 2.3 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.14 PSC68183.1 - 0.022 14.1 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family EFhand_Ca_insen PF08726.10 PSC68183.1 - 0.026 14.6 0.1 12 6.1 0.0 3.9 4 1 0 4 4 4 0 Ca2+ insensitive EF hand DUF5580 PF17743.1 PSC68183.1 - 0.027 13.0 0.0 0.21 10.1 0.0 1.8 1 1 1 2 2 2 0 Family of unknown function (DUF5580) PMBR PF09373.10 PSC68183.1 - 0.028 14.6 0.1 17 5.7 0.0 4.0 4 0 0 4 4 4 0 Pseudomurein-binding repeat Adenine_glyco PF03352.13 PSC68183.1 - 0.046 13.5 0.3 0.18 11.6 0.0 1.9 2 0 0 2 2 2 0 Methyladenine glycosylase VbhA PF18495.1 PSC68183.1 - 0.056 13.3 4.2 10 6.1 0.1 4.0 4 0 0 4 4 4 0 Antitoxin VbhA SnoaL_2 PF12680.7 PSC68183.1 - 0.081 13.6 0.1 0.17 12.6 0.1 1.6 1 0 0 1 1 1 0 SnoaL-like domain Methyltransf_23 PF13489.6 PSC68184.1 - 8.5e-26 90.8 0.0 1.7e-19 70.3 0.0 3.7 3 0 0 3 3 3 3 Methyltransferase domain Methyltransf_25 PF13649.6 PSC68184.1 - 2.8e-22 79.2 3.2 1.3e-11 45.0 0.0 4.6 3 0 0 3 3 3 3 Methyltransferase domain Methyltransf_11 PF08241.12 PSC68184.1 - 1.8e-17 63.8 2.6 1.5e-11 44.8 0.0 4.1 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 PSC68184.1 - 3.9e-15 56.4 0.2 1.3e-10 41.9 0.0 3.5 4 0 0 4 4 3 2 Methyltransferase domain Methyltransf_31 PF13847.6 PSC68184.1 - 2.9e-10 40.1 0.0 1.7e-08 34.4 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC68184.1 - 4.5e-08 32.7 0.0 8.8e-05 21.9 0.0 2.8 3 0 0 3 3 3 2 ubiE/COQ5 methyltransferase family PrmA PF06325.13 PSC68184.1 - 5.2e-07 29.3 2.5 0.0011 18.4 0.6 2.4 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) TPR_1 PF00515.28 PSC68184.1 - 6e-07 29.0 13.7 0.00039 20.1 0.3 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PSC68184.1 - 1e-06 28.4 17.1 0.00065 19.6 1.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PSC68184.1 - 2.6e-05 23.8 12.3 0.00022 20.9 2.6 3.8 1 1 2 3 3 3 2 TPR repeat TPR_19 PF14559.6 PSC68184.1 - 0.001 19.5 5.3 0.001 19.5 5.3 4.3 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 PSC68184.1 - 0.0013 19.0 3.3 1.5 9.4 1.4 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 PSC68184.1 - 0.0035 17.4 8.6 2.6 8.5 0.2 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat RNase_II_C_S1 PF18614.1 PSC68184.1 - 0.012 15.5 1.3 0.091 12.7 1.3 2.6 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain MTS PF05175.14 PSC68184.1 - 0.026 14.1 9.7 0.14 11.7 0.3 3.5 5 0 0 5 5 5 0 Methyltransferase small domain Cons_hypoth95 PF03602.15 PSC68184.1 - 0.049 13.3 1.7 6.4 6.4 0.1 2.4 2 0 0 2 2 2 0 Conserved hypothetical protein 95 TPR_6 PF13174.6 PSC68184.1 - 0.38 11.5 3.4 7.5 7.4 0.2 3.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Methyltransf_16 PF10294.9 PSC68184.1 - 1.1 9.0 2.6 8 6.2 0.0 2.6 3 0 0 3 3 3 0 Lysine methyltransferase TPR_9 PF13371.6 PSC68184.1 - 1.7 8.9 21.3 0.76 10.0 1.5 4.3 2 1 1 3 3 3 0 Tetratricopeptide repeat GMC_oxred_N PF00732.19 PSC68185.1 - 1.2e-41 143.1 0.7 1.2e-41 143.1 0.7 1.8 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PSC68185.1 - 6.1e-20 72.2 0.0 4.5e-19 69.4 0.0 2.4 1 1 0 1 1 1 1 GMC oxidoreductase Collagen PF01391.18 PSC68185.1 - 1.3e-08 34.5 32.2 1.3e-08 34.5 32.2 4.5 6 0 0 6 6 3 1 Collagen triple helix repeat (20 copies) Pyr_redox_2 PF07992.14 PSC68185.1 - 0.00054 19.3 0.4 0.001 18.4 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PSC68185.1 - 0.0017 18.5 0.9 0.02 15.1 0.5 3.1 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 PSC68185.1 - 0.0021 17.3 0.1 0.0076 15.5 0.2 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 PSC68185.1 - 0.0046 16.2 0.5 0.0076 15.5 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 PSC68185.1 - 0.021 14.2 3.6 0.05 13.0 3.6 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 PSC68185.1 - 0.043 12.5 1.0 0.065 11.9 1.0 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 PSC68185.1 - 0.26 10.3 0.6 0.44 9.6 0.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ThiF PF00899.21 PSC68185.1 - 0.49 9.7 3.1 0.22 10.8 0.6 1.6 2 0 0 2 2 2 0 ThiF family GMC_oxred_N PF00732.19 PSC68186.1 - 1.2e-41 143.1 0.7 1.2e-41 143.1 0.7 1.8 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 PSC68186.1 - 6e-20 72.2 0.0 4.4e-19 69.4 0.0 2.4 1 1 0 1 1 1 1 GMC oxidoreductase Collagen PF01391.18 PSC68186.1 - 1.3e-08 34.5 32.2 1.3e-08 34.5 32.2 4.5 6 0 0 6 6 3 1 Collagen triple helix repeat (20 copies) Pyr_redox_2 PF07992.14 PSC68186.1 - 0.00053 19.3 0.4 0.001 18.4 0.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PSC68186.1 - 0.0011 19.1 0.5 0.019 15.2 0.5 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 PSC68186.1 - 0.0021 17.4 0.1 0.0075 15.5 0.2 1.8 2 0 0 2 2 2 1 Thi4 family FAD_binding_3 PF01494.19 PSC68186.1 - 0.0046 16.3 0.5 0.0075 15.6 0.5 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 PSC68186.1 - 0.021 14.2 3.6 0.049 13.0 3.6 1.7 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 PSC68186.1 - 0.043 12.5 1.0 0.064 11.9 1.0 1.2 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 PSC68186.1 - 0.26 10.3 0.6 0.43 9.6 0.6 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A ThiF PF00899.21 PSC68186.1 - 0.48 9.7 3.1 0.22 10.9 0.6 1.6 2 0 0 2 2 2 0 ThiF family 2-oxoacid_dh PF00198.23 PSC68189.1 - 2.9e-78 262.5 0.0 4.2e-78 262.0 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 PSC68189.1 - 1.3e-19 69.8 0.0 2.6e-19 68.8 0.0 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 PSC68189.1 - 8.2e-15 54.9 0.2 3.4e-14 52.9 0.2 2.2 1 0 0 1 1 1 1 e3 binding domain HlyD_3 PF13437.6 PSC68189.1 - 4.4e-05 24.1 0.2 9.5e-05 23.1 0.2 1.6 1 0 0 1 1 1 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 PSC68189.1 - 0.00039 20.2 0.0 0.00039 20.2 0.0 4.3 5 0 0 5 5 5 1 Biotin-lipoyl like SUIM_assoc PF16619.5 PSC68189.1 - 0.0013 18.8 0.8 0.0024 17.9 0.8 1.5 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 HlyD_D23 PF16576.5 PSC68189.1 - 0.0069 15.6 0.2 0.024 13.8 0.2 1.7 1 1 0 1 1 1 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion PYNP_C PF07831.13 PSC68189.1 - 0.0097 15.5 0.1 0.051 13.2 0.0 2.1 2 0 0 2 2 2 1 Pyrimidine nucleoside phosphorylase C-terminal domain Roughex PF06020.11 PSC68189.1 - 0.042 12.9 1.4 0.076 12.1 1.4 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Hist_deacetyl PF00850.19 PSC68190.1 - 7.4e-68 229.3 3.5 3e-67 227.3 3.5 1.9 1 1 0 1 1 1 1 Histone deacetylase domain Branch PF02485.21 PSC68190.1 - 1.8e-34 119.4 0.0 2.6e-34 118.9 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DUF4632 PF15451.6 PSC68190.1 - 0.0085 16.1 0.1 0.028 14.5 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4632) DUF1764 PF08576.10 PSC68191.1 - 2e-23 83.1 1.0 2e-23 83.1 1.0 2.1 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) PX PF00787.24 PSC68192.1 - 3.2e-16 59.3 0.1 5.9e-15 55.2 0.0 2.4 2 0 0 2 2 2 1 PX domain Vps5 PF09325.10 PSC68192.1 - 1.9e-11 44.0 1.8 3e-10 40.0 1.2 2.4 1 1 0 1 1 1 1 Vps5 C terminal like Thioesterase PF00975.20 PSC68192.1 - 0.0072 16.5 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 Thioesterase domain DUF2203 PF09969.9 PSC68192.1 - 0.026 15.2 0.1 0.026 15.2 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) FTA4 PF13093.6 PSC68192.1 - 0.037 13.9 2.4 4 7.3 0.1 2.3 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DegS PF05384.11 PSC68192.1 - 0.22 11.0 5.5 0.69 9.4 0.6 3.2 3 0 0 3 3 3 0 Sensor protein DegS 5_nucleotid PF05761.14 PSC68192.1 - 1.5 7.6 2.7 0.51 9.2 0.1 1.4 2 0 0 2 2 2 0 5' nucleotidase family Peptidase_M50 PF02163.22 PSC68193.1 - 2e-06 27.3 5.5 0.0096 15.2 0.1 3.1 2 1 1 3 3 3 2 Peptidase family M50 rve PF00665.26 PSC68194.1 - 8.3e-19 67.9 0.0 1.8e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC68194.1 - 0.0066 16.2 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Methyltransf_11 PF08241.12 PSC68196.1 - 4e-21 75.5 0.0 9.6e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC68196.1 - 2.1e-18 66.8 0.0 4.4e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 PSC68196.1 - 6.2e-17 61.8 0.0 9.6e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 PSC68196.1 - 3.1e-15 56.4 0.0 5.1e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC68196.1 - 1.8e-13 50.6 0.0 3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC68196.1 - 7.7e-10 39.4 0.0 1.4e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC68196.1 - 4.6e-05 22.9 0.0 7.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 PSC68196.1 - 0.00095 17.8 0.0 0.0014 17.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 PSC68196.1 - 0.0043 16.7 0.0 0.0075 15.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 PSC68196.1 - 0.026 14.6 0.0 0.052 13.7 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 PSC68196.1 - 0.11 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 PSC68196.1 - 0.14 12.2 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 PSC68197.1 - 3.9e-21 75.5 0.0 9.5e-21 74.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC68197.1 - 2.1e-18 66.8 0.0 4.4e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 PSC68197.1 - 6.1e-17 61.8 0.0 9.6e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 PSC68197.1 - 3e-15 56.4 0.0 5e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC68197.1 - 1.7e-13 50.6 0.0 3e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC68197.1 - 7.6e-10 39.4 0.0 1.4e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC68197.1 - 4.6e-05 22.9 0.0 7.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_29 PF03141.16 PSC68197.1 - 0.00095 17.8 0.0 0.0014 17.3 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 PSC68197.1 - 0.0042 16.7 0.0 0.0075 15.9 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW FtsJ PF01728.19 PSC68197.1 - 0.026 14.6 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 PSC68197.1 - 0.11 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 PSC68197.1 - 0.13 12.2 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain CCB1 PF12046.8 PSC68198.1 - 1.2e-55 187.4 0.4 1.9e-55 186.8 0.0 1.5 2 0 0 2 2 2 1 Cofactor assembly of complex C subunit B DUF3930 PF13067.6 PSC68198.1 - 0.015 15.5 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3930) Suf PF05843.14 PSC68198.1 - 0.024 14.6 0.5 1.2 9.0 0.0 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) XRN_N PF03159.18 PSC68199.1 - 1.6e-79 266.7 0.0 3.2e-79 265.8 0.0 1.5 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus XRN_M PF17846.1 PSC68199.1 - 7.4e-49 166.9 0.0 1.9e-32 112.8 0.0 3.1 2 1 0 2 2 2 2 Xrn1 helical domain TFIIA PF03153.13 PSC68199.1 - 5.9 6.8 12.3 0.5 10.3 6.9 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Glyco_transf_90 PF05686.12 PSC68200.1 - 2.3e-35 122.3 0.0 3.5e-35 121.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 Glyco_trans_1_2 PF13524.6 PSC68200.1 - 0.055 13.9 0.0 0.37 11.2 0.0 2.4 1 1 1 2 2 2 0 Glycosyl transferases group 1 PIN_5 PF08745.11 PSC68200.1 - 0.11 11.9 0.0 0.26 10.7 0.0 1.5 2 0 0 2 2 2 0 PINc domain ribonuclease tRNA-synt_2d PF01409.20 PSC68201.1 - 9.9e-49 166.0 0.0 1.7e-48 165.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 PSC68201.1 - 3.1e-26 91.6 0.0 9.4e-26 90.1 0.0 1.9 1 0 0 1 1 1 1 Ferredoxin-fold anticodon binding domain Pkinase PF00069.25 PSC68202.1 - 3.7e-62 210.1 0.0 5.5e-62 209.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GidB PF02527.15 PSC68202.1 - 8.3e-42 142.6 0.0 1e-31 109.7 0.0 2.4 2 0 0 2 2 2 2 rRNA small subunit methyltransferase G TIMELESS PF04821.14 PSC68202.1 - 7.4e-38 130.4 0.0 1.3e-37 129.6 0.0 1.4 1 0 0 1 1 1 1 Timeless protein Cation_ATPase_C PF00689.21 PSC68202.1 - 7.3e-36 123.6 0.1 1.2e-35 122.8 0.1 1.4 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 PSC68202.1 - 9e-34 116.6 0.0 2.2e-33 115.3 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Pkinase_Tyr PF07714.17 PSC68202.1 - 1.7e-30 106.2 0.0 3e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Cation_ATPase PF13246.6 PSC68202.1 - 8e-19 67.5 0.0 1.7e-18 66.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Ank_2 PF12796.7 PSC68202.1 - 7.4e-17 61.7 14.2 1e-05 26.0 1.6 4.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC68202.1 - 4.3e-14 52.7 13.8 0.051 14.2 0.1 7.1 2 2 5 7 7 7 6 Ankyrin repeats (many copies) Hydrolase PF00702.26 PSC68202.1 - 3.1e-09 37.4 9.0 0.00054 20.3 0.0 5.1 4 1 1 5 5 5 3 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PSC68202.1 - 1.2e-07 31.3 0.0 3.4e-07 29.8 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Ank_5 PF13857.6 PSC68202.1 - 1.4e-07 31.6 14.6 0.00052 20.2 1.6 5.6 4 1 1 5 5 5 2 Ankyrin repeats (many copies) TIMELESS_C PF05029.13 PSC68202.1 - 1.5e-07 31.0 8.1 8.2e-07 28.5 0.1 4.5 4 1 1 5 5 5 1 Timeless protein C terminal region Ank PF00023.30 PSC68202.1 - 1.9e-07 31.2 35.0 0.014 15.8 0.1 8.2 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.6 PSC68202.1 - 3.3e-07 30.1 14.0 6 7.8 0.0 7.3 7 0 0 7 7 6 3 Ankyrin repeat Hydrolase_3 PF08282.12 PSC68202.1 - 6e-06 26.2 0.8 1.1e-05 25.3 0.8 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase MTS PF05175.14 PSC68202.1 - 0.012 15.2 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Kinase-like PF14531.6 PSC68202.1 - 0.017 14.4 0.1 0.052 12.8 0.0 1.7 2 0 0 2 2 2 0 Kinase-like Haspin_kinase PF12330.8 PSC68202.1 - 0.1 11.5 0.0 0.16 10.9 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Methyltransf_16 PF10294.9 PSC68202.1 - 0.16 11.7 0.0 0.39 10.4 0.0 1.6 1 0 0 1 1 1 0 Lysine methyltransferase UBX PF00789.20 PSC68203.1 - 2.7e-45 152.4 0.0 2.3e-11 43.7 0.0 4.3 4 0 0 4 4 4 4 UBX domain ASCH PF04266.14 PSC68204.1 - 0.0027 18.3 0.0 0.0043 17.6 0.0 1.4 1 0 0 1 1 1 1 ASCH domain F-box-like PF12937.7 PSC68205.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 F-box-like XPA_C PF05181.12 PSC68205.1 - 0.2 11.7 0.1 0.33 10.9 0.1 1.3 1 0 0 1 1 1 0 XPA protein C-terminus Pkinase PF00069.25 PSC68206.1 - 9.8e-69 231.6 0.0 1.2e-68 231.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC68206.1 - 2.5e-30 105.6 0.0 3.6e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC68206.1 - 0.0069 15.7 0.1 0.84 8.9 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 PSC68206.1 - 0.03 13.3 0.0 0.057 12.4 0.0 1.4 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 PSC68206.1 - 0.041 13.8 0.0 0.096 12.6 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Prolamin_like PF05617.11 PSC68206.1 - 0.08 13.1 0.4 0.16 12.2 0.4 1.4 1 0 0 1 1 1 0 Prolamin-like PRIMA1 PF16101.5 PSC68206.1 - 0.16 12.0 0.7 0.45 10.6 0.7 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Fer2 PF00111.27 PSC68207.1 - 2.3e-15 56.3 0.3 4.5e-15 55.3 0.3 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 PSC68207.1 - 0.058 13.2 1.4 0.16 11.8 1.4 1.7 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Serglycin PF04360.12 PSC68207.1 - 0.16 11.9 0.5 0.26 11.2 0.5 1.4 1 0 0 1 1 1 0 Serglycin Med22 PF06179.12 PSC68208.1 - 2.6e-16 59.7 0.1 6.4e-16 58.5 0.0 1.6 2 0 0 2 2 2 1 Surfeit locus protein 5 subunit 22 of Mediator complex Dynamitin PF04912.14 PSC68208.1 - 0.0098 15.3 1.7 0.012 15.0 1.7 1.1 1 0 0 1 1 1 1 Dynamitin AATF-Che1 PF13339.6 PSC68208.1 - 0.03 15.0 0.8 0.03 15.0 0.8 1.5 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor Spc24 PF08286.11 PSC68208.1 - 0.2 11.9 0.5 0.37 11.0 0.5 1.5 1 0 0 1 1 1 0 Spc24 subunit of Ndc80 DotU PF09850.9 PSC68208.1 - 7.2 6.3 9.5 8.9 6.0 0.4 2.9 2 1 1 3 3 3 0 Type VI secretion system protein DotU Aminotran_5 PF00266.19 PSC68209.1 - 1.5e-135 451.9 0.0 1.9e-135 451.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 PSC68209.1 - 5.6e-09 35.8 0.2 9.7e-09 35.0 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 PSC68209.1 - 0.00012 20.8 0.0 0.0008 18.0 0.0 2.0 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme CbtB PF09489.10 PSC68209.1 - 0.21 11.7 6.8 2 8.6 4.8 2.7 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) RskA PF10099.9 PSC68209.1 - 5.7 7.2 14.2 0.87 9.8 10.0 1.9 2 0 0 2 2 2 0 Anti-sigma-K factor rskA CAP_N PF01213.19 PSC68210.1 - 2.6 7.4 6.5 3.2 7.1 6.5 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 PSC68210.1 - 3.5 7.7 10.6 6.2 6.9 10.6 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Pkinase PF00069.25 PSC68211.1 - 1.7e-07 30.9 0.0 7.3e-06 25.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC68211.1 - 0.012 14.9 0.0 0.61 9.3 0.0 2.3 1 1 1 2 2 2 0 Protein tyrosine kinase Arm PF00514.23 PSC68212.1 - 5.9e-10 38.8 2.6 0.079 13.0 0.0 4.7 4 0 0 4 4 4 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 PSC68212.1 - 1e-07 32.2 5.7 0.00057 20.2 0.2 3.1 1 1 1 2 2 2 2 HEAT repeats HEAT PF02985.22 PSC68212.1 - 4.3e-06 26.5 2.0 1.2 9.6 0.0 4.1 3 0 0 3 3 3 2 HEAT repeat Adaptin_N PF01602.20 PSC68212.1 - 1.2e-05 24.1 0.0 1.7e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_EZ PF13513.6 PSC68212.1 - 0.0005 20.5 0.1 0.0005 20.5 0.1 4.6 4 2 2 6 6 5 2 HEAT-like repeat MOR2-PAG1_C PF14225.6 PSC68212.1 - 0.00056 19.9 0.3 0.0027 17.6 0.0 2.0 2 0 0 2 2 2 1 Cell morphogenesis C-terminal SIL1 PF16782.5 PSC68212.1 - 0.0018 17.5 0.0 0.0038 16.5 0.0 1.6 1 1 0 1 1 1 1 Nucleotide exchange factor SIL1 Fes1 PF08609.10 PSC68212.1 - 0.0057 17.5 0.5 0.027 15.3 0.5 2.3 1 1 0 1 1 1 1 Nucleotide exchange factor Fes1 DUF908 PF06012.12 PSC68212.1 - 0.013 15.0 0.1 0.025 14.0 0.0 1.6 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) Cnd1 PF12717.7 PSC68212.1 - 0.018 15.1 0.0 0.65 10.0 0.0 2.2 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 PSC68212.1 - 0.06 13.5 0.0 13 5.9 0.0 3.3 3 1 0 4 4 4 0 V-ATPase subunit H RIX1 PF08167.12 PSC68212.1 - 0.13 12.0 0.3 5.7 6.6 0.0 2.7 1 1 2 3 3 3 0 rRNA processing/ribosome biogenesis DUF3138 PF11336.8 PSC68212.1 - 4.7 5.7 9.8 0.53 8.8 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Chorein_N PF12624.7 PSC68214.1 - 8.2e-09 35.6 0.0 1.6e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 Mannosyl_trans PF05007.13 PSC68215.1 - 2.2e-62 211.3 0.2 1.3e-61 208.7 0.2 1.9 1 1 0 1 1 1 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 PSC68215.1 - 4.5e-12 45.7 0.0 9.2e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U GT87 PF09594.10 PSC68215.1 - 0.002 17.9 39.8 0.002 17.9 39.8 4.3 2 1 0 3 3 3 1 Glycosyltransferase family 87 DUF4307 PF14155.6 PSC68215.1 - 6.1 6.7 11.7 0.18 11.6 0.7 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4307) Cystatin PF00031.21 PSC68216.1 - 0.09 13.1 0.0 0.3 11.4 0.0 1.9 2 0 0 2 2 2 0 Cystatin domain zf-Tim10_DDP PF02953.15 PSC68217.1 - 1.1e-17 63.4 2.1 4.3e-17 61.5 2.1 2.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger LAP1C PF05609.12 PSC68217.1 - 7.6 5.5 50.9 1.1 8.3 39.9 2.2 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Cupin_8 PF13621.6 PSC68218.1 - 3e-44 151.6 0.0 6.2e-44 150.6 0.0 1.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 PSC68218.1 - 2e-10 40.6 0.1 4.4e-10 39.5 0.1 1.5 1 0 0 1 1 1 1 Cupin superfamily protein Glutaredoxin PF00462.24 PSC68218.1 - 1.9e-06 28.0 0.0 9.8e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 Glutaredoxin SH3BGR PF04908.15 PSC68218.1 - 0.0014 18.7 0.0 0.0029 17.7 0.0 1.5 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein JmjC PF02373.22 PSC68218.1 - 0.0025 18.2 0.1 0.01 16.2 0.1 2.0 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.11 PSC68218.1 - 0.028 14.1 0.1 0.12 12.1 0.0 2.2 2 0 0 2 2 2 0 Cupin domain WLM PF08325.10 PSC68219.1 - 4e-45 154.2 0.0 7.5e-45 153.4 0.0 1.5 1 0 0 1 1 1 1 WLM domain Nucleotid_trans PF03407.16 PSC68219.1 - 6.6e-16 58.9 0.0 1.6e-15 57.7 0.0 1.6 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Transcrip_act PF04949.13 PSC68219.1 - 1.2e-09 38.2 3.8 2.1e-09 37.4 3.8 1.3 1 0 0 1 1 1 1 Transcriptional activator LRR_8 PF13855.6 PSC68219.1 - 0.0037 17.0 0.8 2.6 7.9 0.0 3.9 3 0 0 3 3 3 1 Leucine rich repeat rve PF00665.26 PSC68219.1 - 0.014 15.5 0.0 0.044 14.0 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain F-box-like PF12937.7 PSC68219.1 - 0.019 14.8 1.6 0.9 9.5 0.0 3.0 2 0 0 2 2 2 0 F-box-like DUF45 PF01863.17 PSC68219.1 - 0.21 11.6 0.0 0.21 11.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF45 Spc7 PF08317.11 PSC68219.1 - 3.2 6.5 12.1 5.4 5.8 12.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein FadA PF09403.10 PSC68219.1 - 3.3 8.2 9.0 9 6.8 9.0 1.7 1 0 0 1 1 1 0 Adhesion protein FadA Exonuc_VII_L PF02601.15 PSC68219.1 - 5.8 6.4 9.3 4.4 6.8 7.6 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit Trypsin PF00089.26 PSC68221.1 - 5.2e-50 170.3 0.0 7.2e-50 169.8 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PSC68221.1 - 9.5e-06 26.6 0.5 2.6e-05 25.2 0.5 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 PSC68222.1 - 6.7e-49 166.7 0.0 7.9e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PSC68222.1 - 6.2e-06 27.2 0.6 1.4e-05 26.0 0.6 1.6 1 1 0 1 1 1 1 Trypsin-like peptidase domain Pro_isomerase PF00160.21 PSC68223.1 - 4.9e-32 111.4 0.1 9.5e-32 110.5 0.1 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Cofilin_ADF PF00241.20 PSC68223.1 - 1.5e-30 105.5 0.0 2.5e-30 104.8 0.0 1.3 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein PAN_4 PF14295.6 PSC68223.1 - 2.5e-07 30.5 8.8 4.5e-07 29.7 8.8 1.4 1 0 0 1 1 1 1 PAN domain SUIM_assoc PF16619.5 PSC68223.1 - 1.7 8.8 7.3 54 3.9 0.0 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 WW PF00397.26 PSC68224.1 - 2.6e-19 69.0 23.1 4.5e-13 49.0 2.0 2.8 3 0 0 3 3 3 2 WW domain Glyco_hyd_101C PF17451.2 PSC68224.1 - 0.28 11.5 2.9 11 6.4 0.2 2.6 1 1 1 2 2 2 0 Glycosyl hydrolase 101 beta sandwich domain cwf18 PF08315.12 PSC68224.1 - 0.49 11.0 3.3 0.98 10.1 3.3 1.4 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor RVT_2 PF07727.14 PSC68225.1 - 2e-74 250.3 0.0 2.6e-74 249.9 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Crr6 PF08847.11 PSC68225.1 - 0.06 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Chlororespiratory reduction 6 Glyco_hydro_18 PF00704.28 PSC68226.1 - 2.5e-12 47.2 0.0 3.3e-10 40.2 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolases family 18 DUF4378 PF14309.6 PSC68227.1 - 0.0012 19.2 0.0 0.0015 18.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4378) RRM_1 PF00076.22 PSC68228.1 - 2.1e-20 72.3 0.0 5.3e-11 42.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PSC68228.1 - 4.4e-07 29.9 0.1 0.013 15.6 0.0 3.1 3 1 0 3 3 3 2 RNA recognition motif zf-RanBP PF00641.18 PSC68228.1 - 0.00052 19.3 9.2 0.00086 18.6 9.2 1.3 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others Sybindin PF04099.12 PSC68229.1 - 7.3e-33 113.5 0.0 8.2e-33 113.3 0.0 1.0 1 0 0 1 1 1 1 Sybindin-like family APG9 PF04109.16 PSC68230.1 - 4.3e-163 543.8 8.4 5.8e-163 543.3 8.4 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 zf_C2H2_10 PF18414.1 PSC68230.1 - 0.0095 15.4 1.8 0.019 14.5 1.8 1.5 1 0 0 1 1 1 1 C2H2 type zinc-finger TFIIA PF03153.13 PSC68230.1 - 0.11 12.5 24.0 0.17 11.9 24.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SARAF PF06682.12 PSC68230.1 - 0.34 10.5 11.1 0.58 9.7 11.1 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis zf-CCHC_2 PF13696.6 PSC68230.1 - 0.34 10.8 1.5 0.63 9.9 1.5 1.5 1 0 0 1 1 1 0 Zinc knuckle Hydin_ADK PF17213.3 PSC68230.1 - 0.92 9.8 3.9 1.7 8.9 3.9 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Hamartin PF04388.12 PSC68230.1 - 1.1 7.8 5.4 1.6 7.3 5.4 1.1 1 0 0 1 1 1 0 Hamartin protein Amidase PF01425.21 PSC68230.1 - 1.2 8.0 5.1 2.1 7.2 5.1 1.2 1 0 0 1 1 1 0 Amidase PALP PF00291.25 PSC68231.1 - 3.2e-82 276.2 8.9 3.2e-82 276.2 8.9 1.5 2 0 0 2 2 2 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 PSC68231.1 - 4.5e-32 109.7 0.0 6.3e-18 64.3 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase IFRD PF05004.13 PSC68232.1 - 1e-55 189.1 0.1 4.8e-49 167.1 0.0 2.1 2 0 0 2 2 2 2 Interferon-related developmental regulator (IFRD) TRAP_alpha PF03896.16 PSC68232.1 - 4.3e-08 32.7 0.4 7.6e-08 31.9 0.0 1.5 2 0 0 2 2 2 1 Translocon-associated protein (TRAP), alpha subunit DUF4042 PF13251.6 PSC68232.1 - 0.0044 16.7 0.0 0.009 15.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4042) IFRD_C PF04836.12 PSC68232.1 - 0.035 14.7 0.4 0.084 13.5 0.4 1.7 1 0 0 1 1 1 0 Interferon-related protein conserved region Ank_2 PF12796.7 PSC68233.1 - 1.2e-22 80.3 1.3 1.2e-09 38.6 0.1 4.2 2 1 3 5 5 5 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC68233.1 - 1.5e-17 63.4 5.7 1e-06 28.9 0.3 5.2 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 PSC68233.1 - 7.3e-14 51.5 8.0 1.9e-05 24.9 0.0 5.1 5 0 0 5 5 5 3 Ankyrin repeat Ank_3 PF13606.6 PSC68233.1 - 1.2e-12 46.8 6.0 0.0013 19.0 0.0 6.2 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 PSC68233.1 - 3.6e-11 43.4 4.5 3.9e-05 24.1 0.0 5.5 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Tweety PF04906.13 PSC68234.1 - 0.14 10.8 0.0 0.19 10.3 0.0 1.1 1 0 0 1 1 1 0 Tweety Nucleotid_trans PF03407.16 PSC68235.1 - 2.4e-05 24.4 0.1 5.1e-05 23.4 0.1 1.5 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase CBM_20 PF00686.19 PSC68236.1 - 1e-17 63.8 0.0 1.3e-17 63.4 0.0 1.1 1 0 0 1 1 1 1 Starch binding domain MPC PF03650.13 PSC68237.1 - 1.6e-32 111.9 0.6 1.9e-32 111.7 0.6 1.1 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers DUF3439 PF11921.8 PSC68237.1 - 0.091 12.7 0.1 0.12 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) tRNA-synt_1d PF00750.19 PSC68238.1 - 9.7e-125 416.1 0.0 1.5e-124 415.5 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (R) SE PF08491.10 PSC68238.1 - 1.6e-103 345.6 0.0 2.4e-103 345.0 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase DALR_1 PF05746.15 PSC68238.1 - 4.9e-30 104.1 0.7 4.9e-30 104.1 0.7 2.4 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 PSC68238.1 - 1.6e-18 67.1 0.8 3.5e-18 66.0 0.1 2.0 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain FAD_binding_3 PF01494.19 PSC68238.1 - 8.1e-09 35.2 0.1 3.1e-08 33.3 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain tRNA-synt_1e PF01406.19 PSC68238.1 - 0.073 12.4 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Thi4 PF01946.17 PSC68238.1 - 0.13 11.5 0.0 0.32 10.2 0.0 1.6 1 0 0 1 1 1 0 Thi4 family Presenilin PF01080.17 PSC68238.1 - 1.5 7.5 8.0 3 6.5 8.0 1.5 1 0 0 1 1 1 0 Presenilin Ku PF02735.16 PSC68239.1 - 3.2e-21 76.0 0.0 3.2e-17 62.9 0.0 2.3 1 1 1 2 2 2 2 Ku70/Ku80 beta-barrel domain SAP PF02037.27 PSC68239.1 - 1.2e-09 37.6 0.0 2.3e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 SAP domain Ku_N PF03731.15 PSC68239.1 - 1.2e-07 31.8 0.0 2e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 PSC68239.1 - 7.8e-07 29.7 0.6 2.5e-06 28.1 0.6 1.9 1 1 0 1 1 1 1 Ku70/Ku80 C-terminal arm Ish1 PF10281.9 PSC68239.1 - 0.01 16.1 0.2 0.028 14.7 0.0 1.9 2 0 0 2 2 2 0 Putative stress-responsive nuclear envelope protein NAD_binding_10 PF13460.6 PSC68240.1 - 1.1e-43 149.3 0.0 1.6e-43 148.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 PSC68240.1 - 3e-19 69.5 0.1 4.1e-19 69.1 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 PSC68240.1 - 3.7e-11 42.9 0.0 5.8e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PSC68240.1 - 8.8e-10 38.0 0.1 1.2e-09 37.6 0.1 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 PSC68240.1 - 6.2e-05 22.5 0.6 0.00012 21.6 0.6 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 PSC68240.1 - 0.0015 17.7 0.5 0.0033 16.6 0.5 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 PSC68240.1 - 0.0022 17.1 0.2 0.011 14.9 0.2 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 PSC68240.1 - 0.02 14.1 0.6 6.3 5.9 0.3 3.0 3 0 0 3 3 3 0 Male sterility protein KR PF08659.10 PSC68240.1 - 0.026 14.4 0.4 0.22 11.4 0.3 2.2 2 0 0 2 2 2 0 KR domain GDP_Man_Dehyd PF16363.5 PSC68240.1 - 0.27 10.6 0.1 0.88 8.9 0.1 1.7 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase zf-CHCC PF10276.9 PSC68241.1 - 0.00027 20.9 0.0 0.0011 19.0 0.0 1.9 2 0 0 2 2 2 1 Zinc-finger domain ATG16 PF08614.11 PSC68242.1 - 0.0022 18.2 11.1 0.0022 18.2 11.1 5.3 1 1 3 4 4 4 3 Autophagy protein 16 (ATG16) Sec23_trunk PF04811.15 PSC68242.1 - 1.3 8.6 4.4 0.53 9.8 1.0 2.1 2 1 0 2 2 2 0 Sec23/Sec24 trunk domain dCMP_cyt_deam_2 PF08211.12 PSC68243.1 - 4.1e-40 137.1 0.3 1.2e-39 135.6 0.1 1.9 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_1 PF00383.23 PSC68243.1 - 1.5e-13 50.4 0.2 8.4e-10 38.4 0.0 2.5 2 0 0 2 2 2 2 Cytidine and deoxycytidylate deaminase zinc-binding region C2 PF00168.30 PSC68243.1 - 1.5e-10 41.3 0.0 2.8e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain Thioredoxin PF00085.20 PSC68245.1 - 2.5e-10 40.2 0.0 2.7e-10 40.2 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PSC68245.1 - 0.00049 20.5 0.0 0.00051 20.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Sep15_SelM PF08806.11 PSC68245.1 - 0.0073 16.4 0.0 0.0084 16.2 0.0 1.1 1 0 0 1 1 1 1 Sep15/SelM redox domain KaiB PF07689.12 PSC68245.1 - 0.029 14.1 0.0 0.033 13.9 0.0 1.1 1 0 0 1 1 1 0 KaiB domain Ysc84 PF04366.12 PSC68246.1 - 8.6e-07 28.8 0.0 2.1e-06 27.5 0.0 1.7 2 0 0 2 2 2 1 Las17-binding protein actin regulator Glyco_hydro_31 PF01055.26 PSC68247.1 - 4.8e-143 477.5 0.6 6.3e-143 477.1 0.6 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Galactosyl_T PF01762.21 PSC68247.1 - 7.2e-31 107.5 0.0 1.1e-30 107.0 0.0 1.3 1 0 0 1 1 1 1 Galactosyltransferase Gal_mutarotas_2 PF13802.6 PSC68247.1 - 5.8e-21 74.6 0.1 1.8e-19 69.8 0.0 3.0 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 PSC68247.1 - 1.8e-06 28.1 0.0 4.7e-06 26.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF5110) Lipase_GDSL_2 PF13472.6 PSC68247.1 - 8.1e-05 23.1 0.0 0.00022 21.7 0.0 1.7 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Sec3_C PF09763.9 PSC68248.1 - 1.1e-38 133.1 0.0 1.5e-24 86.4 0.0 3.1 3 0 0 3 3 3 3 Exocyst complex component Sec3 DUF935 PF06074.12 PSC68248.1 - 0.0014 17.5 4.9 0.0014 17.5 4.9 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF935) Sec3-PIP2_bind PF15277.6 PSC68248.1 - 0.0044 17.1 0.0 0.0076 16.4 0.0 1.4 1 0 0 1 1 1 1 Exocyst complex component SEC3 N-terminal PIP2 binding PH SUIM_assoc PF16619.5 PSC68248.1 - 0.012 15.6 17.3 0.49 10.5 0.9 3.1 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 PSC68248.1 - 0.016 14.8 13.0 0.49 10.0 6.3 2.2 2 0 0 2 2 2 0 Spt20 family DUF2722 PF10846.8 PSC68248.1 - 0.034 13.1 4.7 0.18 10.7 1.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Glypican PF01153.19 PSC68248.1 - 0.17 10.7 1.3 0.34 9.7 1.3 1.4 1 0 0 1 1 1 0 Glypican Vps52 PF04129.12 PSC68248.1 - 0.18 10.5 0.0 0.25 10.0 0.0 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family SARAF PF06682.12 PSC68248.1 - 0.93 9.1 7.3 1.5 8.4 2.2 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis ANAPC_CDC26 PF10471.9 PSC68248.1 - 1.5 9.7 18.0 3.3 8.6 1.4 3.5 3 0 0 3 3 3 0 Anaphase-promoting complex APC subunit CDC26 LTXXQ PF07813.12 PSC68249.1 - 0.0085 16.8 0.3 0.0085 16.8 0.3 2.6 3 0 0 3 3 3 1 LTXXQ motif family protein REGB_T4 PF10715.9 PSC68249.1 - 0.058 13.6 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 T4-page Endoribonuclease RegB Lipocalin_2 PF08212.12 PSC68250.1 - 9.6e-05 22.3 0.0 0.0097 15.8 0.0 2.2 1 1 0 1 1 1 1 Lipocalin-like domain Lipocalin PF00061.23 PSC68250.1 - 0.00033 20.9 0.0 0.0048 17.1 0.0 2.0 2 0 0 2 2 2 1 Lipocalin / cytosolic fatty-acid binding protein family KDZ PF18758.1 PSC68251.1 - 8.3e-05 22.3 0.0 0.27 10.8 0.0 2.3 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase Pkinase PF00069.25 PSC68252.1 - 2.3e-56 191.1 0.0 3.3e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC68252.1 - 6.3e-25 87.9 0.0 1.1e-24 87.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF707 PF05212.12 PSC68252.1 - 4.8e-10 39.2 0.0 0.019 14.2 0.0 4.2 2 2 0 2 2 2 2 Protein of unknown function (DUF707) Kdo PF06293.14 PSC68252.1 - 7.4e-06 25.5 0.1 1.3e-05 24.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PSC68252.1 - 0.00035 20.0 0.0 0.001 18.5 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Glyco_transf_64 PF09258.10 PSC68252.1 - 0.11 11.7 0.0 0.71 9.1 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 64 domain Choline_kinase PF01633.20 PSC68252.1 - 0.27 10.8 0.0 0.94 9.0 0.0 1.8 1 1 0 1 1 1 0 Choline/ethanolamine kinase PP2C PF00481.21 PSC68254.1 - 8.2e-29 101.0 0.1 9.8e-29 100.8 0.1 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PSC68254.1 - 0.0038 16.9 0.0 0.0085 15.7 0.0 1.6 1 1 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 PSC68255.1 - 9e-10 38.2 0.1 0.00024 20.8 0.0 4.6 4 1 0 4 4 4 2 Leucine rich repeat F-box-like PF12937.7 PSC68255.1 - 0.00065 19.6 0.4 0.0016 18.3 0.4 1.8 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 PSC68255.1 - 0.0012 19.1 1.9 23 6.0 0.0 5.2 6 0 0 6 6 6 2 Leucine Rich Repeat LRR_4 PF12799.7 PSC68255.1 - 0.0038 17.6 0.6 2.5 8.6 0.0 4.3 4 2 2 6 6 6 1 Leucine Rich repeats (2 copies) Pkinase PF00069.25 PSC68256.1 - 2.1e-21 76.5 0.0 8.3e-21 74.5 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC68256.1 - 6.8e-13 48.5 0.0 1.3e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FF PF01846.19 PSC68256.1 - 3.5e-06 27.1 0.0 0.69 10.1 0.0 3.5 3 0 0 3 3 3 3 FF domain Kdo PF06293.14 PSC68256.1 - 0.00022 20.6 0.0 0.00052 19.4 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PSC68256.1 - 0.0031 16.3 0.0 0.0076 15.1 0.0 1.5 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PSC68256.1 - 0.0033 17.4 0.2 0.0033 17.4 0.2 4.5 2 2 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PSC68256.1 - 0.024 14.0 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like FTA2 PF13095.6 PSC68256.1 - 0.12 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 RRM_1 PF00076.22 PSC68257.1 - 3.7e-41 138.8 0.0 1.5e-14 53.5 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SpoIIE PF07228.12 PSC68257.1 - 3.2e-11 43.5 0.3 1e-10 41.9 0.3 1.9 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) Myb_CC_LHEQLE PF14379.6 PSC68257.1 - 0.0062 16.2 1.3 0.013 15.2 1.3 1.5 1 0 0 1 1 1 1 MYB-CC type transfactor, LHEQLE motif RRM_occluded PF16842.5 PSC68257.1 - 0.015 15.2 0.0 1.3 8.9 0.0 2.9 3 0 0 3 3 3 0 Occluded RNA-recognition motif PP2C PF00481.21 PSC68257.1 - 0.029 14.0 0.0 2.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein phosphatase 2C ApbA PF02558.16 PSC68258.1 - 2.3e-06 27.3 0.3 2.1e-05 24.2 0.2 2.2 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 PSC68258.1 - 4.3e-06 27.2 0.1 2e-05 25.1 0.1 2.2 3 1 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 PSC68258.1 - 0.00051 20.3 0.0 0.0029 17.8 0.0 2.0 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 PSC68258.1 - 0.0052 16.7 0.0 0.077 12.9 0.1 2.1 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 PSC68258.1 - 0.095 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2-Hacid_dh_C PF02826.19 PSC68258.1 - 0.13 11.6 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3228 PF11539.8 PSC68259.1 - 7.7e-77 257.2 0.0 8.7e-77 257.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3228) rve PF00665.26 PSC68261.1 - 2.6e-18 66.3 0.0 6.9e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain ADH_N PF08240.12 PSC68261.1 - 2.9e-15 56.1 1.5 6.3e-11 42.1 0.2 3.8 4 0 0 4 4 4 2 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PSC68261.1 - 7.3e-06 26.0 0.1 5.3e-05 23.2 0.1 2.4 1 1 0 1 1 1 1 Zinc-binding dehydrogenase VWD PF00094.25 PSC68261.1 - 0.012 15.9 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type D domain ADH_zinc_N_2 PF13602.6 PSC68261.1 - 0.016 16.3 0.0 0.06 14.4 0.0 2.0 1 0 0 1 1 1 0 Zinc-binding dehydrogenase rve_3 PF13683.6 PSC68261.1 - 0.023 14.4 0.0 0.059 13.1 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain LSM PF01423.22 PSC68263.1 - 1.4e-05 24.6 0.0 1.7e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 PSC68263.1 - 0.0062 16.7 0.0 0.0086 16.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain KDZ PF18758.1 PSC68264.1 - 3.5e-24 85.7 0.7 5e-24 85.2 0.7 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF2269 PF10027.9 PSC68264.1 - 0.0025 17.9 0.9 0.0058 16.7 0.9 1.7 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) HA2 PF04408.23 PSC68265.1 - 3.9e-17 62.5 0.0 1.1e-16 61.0 0.0 1.8 1 0 0 1 1 1 1 Helicase associated domain (HA2) R3H PF01424.22 PSC68265.1 - 3.5e-12 46.1 0.0 7.3e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 R3H domain OB_NTP_bind PF07717.16 PSC68265.1 - 9.9e-11 41.9 0.0 1.9e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PSC68265.1 - 2e-10 41.0 0.0 4.2e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PSC68265.1 - 1.5e-08 34.6 0.0 3.4e-08 33.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Ank_2 PF12796.7 PSC68265.1 - 1.6e-05 25.4 0.0 5.3e-05 23.7 0.0 1.9 2 0 0 2 2 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 PSC68265.1 - 0.00025 21.3 0.1 0.0027 18.1 0.2 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 PSC68265.1 - 0.00099 19.4 0.2 0.006 16.9 0.1 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) ATPase PF06745.13 PSC68265.1 - 0.0046 16.3 0.0 0.0082 15.5 0.0 1.3 1 0 0 1 1 1 1 KaiC Ank_3 PF13606.6 PSC68265.1 - 0.01 16.3 0.0 0.04 14.4 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeat AAA_22 PF13401.6 PSC68265.1 - 0.016 15.5 0.0 0.044 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Ank_4 PF13637.6 PSC68265.1 - 0.055 14.1 0.0 0.18 12.4 0.0 1.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) SnoaL_2 PF12680.7 PSC68265.1 - 0.059 14.0 0.4 0.059 14.0 0.4 3.2 4 1 0 4 4 2 0 SnoaL-like domain Sigma54_activat PF00158.26 PSC68265.1 - 0.061 13.0 0.0 0.38 10.4 0.0 2.3 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_19 PF13245.6 PSC68265.1 - 0.078 13.3 0.0 0.21 11.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 PSC68265.1 - 0.14 12.6 0.0 0.3 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 PSC68265.1 - 0.22 11.0 0.0 0.39 10.1 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein Spt5_N PF11942.8 PSC68265.1 - 0.86 10.6 7.2 2.6 9.1 0.5 2.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal BCIP PF13862.6 PSC68266.1 - 1.6e-40 139.1 0.0 2.2e-40 138.6 0.0 1.2 1 0 0 1 1 1 1 p21-C-terminal region-binding protein PBP_like_2 PF12849.7 PSC68266.1 - 1.7e-10 41.1 0.0 1.8e-09 37.7 0.0 2.2 2 0 0 2 2 2 1 PBP superfamily domain ATP19 PF11022.8 PSC68266.1 - 0.21 11.9 0.9 3 8.3 0.0 3.1 3 0 0 3 3 3 0 ATP synthase subunit K Tecti-min-caps PF09300.10 PSC68266.1 - 0.37 10.9 4.3 2.8 8.1 0.0 2.6 2 0 0 2 2 2 0 Tectiviridae, minor capsid Ins_P5_2-kin PF06090.12 PSC68267.1 - 8.7e-68 229.2 0.0 1.1e-67 228.8 0.0 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Suf PF05843.14 PSC68267.1 - 0.06 13.3 0.4 0.098 12.6 0.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ChAPs PF09295.10 PSC68268.1 - 0.014 14.4 0.7 0.014 14.4 0.7 1.6 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) eIF-3_zeta PF05091.12 PSC68268.1 - 0.28 10.1 8.8 0.53 9.2 8.8 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 PSC68268.1 - 6.8 7.7 11.7 16 6.5 11.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) ChAPs PF09295.10 PSC68269.1 - 0.014 14.4 0.7 0.014 14.4 0.7 1.6 2 0 0 2 2 2 0 ChAPs (Chs5p-Arf1p-binding proteins) eIF-3_zeta PF05091.12 PSC68269.1 - 0.28 10.1 8.8 0.53 9.2 8.8 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4834 PF16118.5 PSC68269.1 - 6.8 7.7 11.7 16 6.5 11.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Pmp3 PF01679.17 PSC68270.1 - 1e-16 60.8 5.9 1.2e-16 60.6 5.9 1.1 1 0 0 1 1 1 1 Proteolipid membrane potential modulator RTC4 PF14474.6 PSC68270.1 - 0.25 11.5 0.1 0.32 11.2 0.1 1.1 1 0 0 1 1 1 0 RTC4-like domain NapE PF06796.11 PSC68270.1 - 0.89 9.1 5.2 0.98 9.0 3.2 2.0 1 1 1 2 2 2 0 Periplasmic nitrate reductase protein NapE Acetyltransf_1 PF00583.25 PSC68271.1 - 5.6e-07 29.8 0.5 3.4e-06 27.3 0.1 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family FR47 PF08445.10 PSC68271.1 - 3.1e-05 23.9 0.0 5.7e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 PSC68271.1 - 9.7e-05 22.3 0.1 0.0002 21.3 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PSC68271.1 - 0.00035 20.9 0.1 0.00091 19.6 0.1 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain PilZ_2 PF16823.5 PSC68271.1 - 0.018 15.2 0.0 0.032 14.4 0.0 1.5 1 0 0 1 1 1 0 Atypical PilZ domain, cyclic di-GMP receptor PPR_2 PF13041.6 PSC68272.1 - 1.2e-83 275.1 4.5 3.9e-15 55.8 0.0 9.1 2 1 7 9 9 9 8 PPR repeat family PPR PF01535.20 PSC68272.1 - 2.2e-65 212.5 5.4 3.5e-10 39.4 0.0 10.1 10 0 0 10 10 10 8 PPR repeat PPR_1 PF12854.7 PSC68272.1 - 1.3e-63 210.3 0.0 3.3e-09 36.3 0.0 10.2 10 0 0 10 10 10 9 PPR repeat PPR_3 PF13812.6 PSC68272.1 - 1.1e-60 201.6 0.0 3.4e-17 62.3 0.0 5.5 4 1 1 5 5 5 5 Pentatricopeptide repeat domain PPR_long PF17177.4 PSC68272.1 - 1.9e-33 115.7 0.0 2e-19 69.8 0.1 2.6 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP DEAD PF00270.29 PSC68272.1 - 1e-19 71.0 0.0 2.7e-19 69.6 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC68272.1 - 7.1e-18 65.0 0.0 1.5e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Wzy_C_2 PF11846.8 PSC68272.1 - 7e-05 22.8 0.3 0.47 10.3 0.0 3.8 2 1 1 3 3 3 2 Virulence factor membrane-bound polymerase, C-terminal TPR_7 PF13176.6 PSC68272.1 - 9.5e-05 22.2 12.5 16 5.8 0.1 7.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Clathrin PF00637.20 PSC68272.1 - 0.0002 21.2 0.0 0.13 12.2 0.0 3.4 2 1 1 3 3 3 1 Region in Clathrin and VPS TPR_1 PF00515.28 PSC68272.1 - 0.00022 20.9 2.3 6.7 6.7 0.0 5.7 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 PSC68272.1 - 0.00038 20.7 18.1 0.061 13.6 0.3 5.9 3 1 4 7 7 7 4 Tetratricopeptide repeat PYRIN PF02758.16 PSC68272.1 - 0.001 19.2 0.8 15 5.8 0.0 5.7 7 0 0 7 7 7 0 PAAD/DAPIN/Pyrin domain MRP-S27 PF10037.9 PSC68272.1 - 0.0039 16.1 0.0 0.0039 16.1 0.0 2.3 2 1 0 2 2 1 1 Mitochondrial 28S ribosomal protein S27 DUF3851 PF12962.7 PSC68272.1 - 0.005 17.1 2.5 0.015 15.6 2.5 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3851) ATP13 PF12921.7 PSC68272.1 - 0.012 15.5 0.0 0.34 10.8 0.0 2.9 2 1 1 3 3 3 0 Mitochondrial ATPase expression Coatomer_E PF04733.14 PSC68272.1 - 0.028 13.9 0.2 6.8 6.0 0.0 2.4 2 0 0 2 2 2 0 Coatomer epsilon subunit TPR_6 PF13174.6 PSC68272.1 - 0.6 10.9 15.9 65 4.5 0.0 7.9 8 0 0 8 8 7 0 Tetratricopeptide repeat TPR_2 PF07719.17 PSC68272.1 - 0.79 10.0 13.9 60 4.1 0.1 6.9 7 0 0 7 7 7 0 Tetratricopeptide repeat Diphthamide_syn PF01866.17 PSC68273.1 - 4e-51 174.3 0.0 4.8e-31 108.3 0.0 2.2 2 0 0 2 2 2 2 Putative diphthamide synthesis protein rve PF00665.26 PSC68273.1 - 2e-18 66.7 0.0 4.9e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Peptidase_C15 PF01470.17 PSC68273.1 - 5.1e-05 23.5 0.0 0.0001 22.6 0.0 1.4 1 0 0 1 1 1 1 Pyroglutamyl peptidase rve_3 PF13683.6 PSC68273.1 - 0.016 15.0 0.0 0.044 13.6 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain DPBB_1 PF03330.18 PSC68274.1 - 7.1e-09 35.8 0.8 1.8e-08 34.6 0.1 2.0 2 0 0 2 2 2 1 Lytic transglycolase PCI PF01399.27 PSC68274.1 - 0.018 15.5 0.0 0.031 14.8 0.0 1.4 1 0 0 1 1 1 0 PCI domain CSN7a_helixI PF18392.1 PSC68274.1 - 0.14 12.1 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain Rhomboid PF01694.22 PSC68275.1 - 1.1e-27 96.9 13.4 1.7e-27 96.3 13.4 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 PSC68275.1 - 0.091 13.3 0.6 0.21 12.2 0.6 1.7 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) DEAD PF00270.29 PSC68276.1 - 5.8e-49 166.2 0.0 1.5e-48 164.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC68276.1 - 1.2e-26 93.3 0.0 2.4e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC68276.1 - 0.00096 19.2 0.0 0.0025 17.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PSC68277.1 - 5.8e-49 166.2 0.0 1.5e-48 164.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC68277.1 - 1.2e-26 93.3 0.0 2.4e-26 92.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC68277.1 - 0.00096 19.2 0.0 0.0025 17.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Tubulin PF00091.25 PSC68278.1 - 8.4e-52 176.2 0.0 1.5e-51 175.4 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain RSN1_7TM PF02714.15 PSC68278.1 - 2.3e-37 128.8 14.2 4.1e-37 128.0 14.2 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 PSC68278.1 - 3.9e-28 98.2 0.4 3.9e-28 98.2 0.4 3.6 5 0 0 5 5 5 1 Late exocytosis, associated with Golgi transport Tubulin_C PF03953.17 PSC68278.1 - 1.2e-16 61.0 0.0 7.9e-16 58.4 0.0 2.0 2 0 0 2 2 2 1 Tubulin C-terminal domain PHM7_cyt PF14703.6 PSC68278.1 - 5e-08 33.4 0.0 1.3e-07 32.1 0.0 1.7 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Tubulin_2 PF13809.6 PSC68278.1 - 0.047 12.9 0.0 0.079 12.1 0.0 1.2 1 0 0 1 1 1 0 Tubulin like Tubulin_3 PF14881.6 PSC68278.1 - 0.09 12.5 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 Tubulin domain Leo1 PF04004.13 PSC68279.1 - 2.1e-40 138.3 1.2 3.1e-40 137.7 0.0 1.9 2 0 0 2 2 2 1 Leo1-like protein Presenilin PF01080.17 PSC68279.1 - 2.1 7.0 5.2 3.7 6.2 5.2 1.3 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 PSC68279.1 - 3.6 7.1 8.1 6.5 6.3 8.1 1.3 1 0 0 1 1 1 0 Spt20 family Nop14 PF04147.12 PSC68279.1 - 6.4 4.8 26.6 9.7 4.3 26.6 1.1 1 0 0 1 1 1 0 Nop14-like family HA2 PF04408.23 PSC68280.1 - 3.5e-24 85.2 1.2 3.5e-24 85.2 1.2 3.0 3 1 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PSC68280.1 - 1.8e-17 63.4 0.0 3.7e-17 62.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PSC68280.1 - 5.6e-07 29.9 0.0 2.2e-06 28.0 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 PSC68280.1 - 0.00054 20.2 1.0 0.0011 19.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 PSC68280.1 - 0.0007 19.4 0.0 0.0013 18.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_23 PF13476.6 PSC68280.1 - 0.0021 18.6 0.9 2.8 8.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 PSC68280.1 - 0.024 13.7 0.1 0.048 12.7 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein ATPase PF06745.13 PSC68280.1 - 0.11 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 KaiC AF-4 PF05110.13 PSC68280.1 - 0.25 9.4 10.9 0.45 8.5 10.9 1.4 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Serglycin PF04360.12 PSC68280.1 - 1.3 9.0 6.1 3.3 7.7 6.1 1.6 1 0 0 1 1 1 0 Serglycin SEEEED PF14797.6 PSC68280.1 - 2.6 8.2 18.9 0.042 14.0 6.1 2.6 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex SR-25 PF10500.9 PSC68282.1 - 0.068 12.8 2.4 0.095 12.3 2.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SR-25 PF10500.9 PSC68283.1 - 0.068 12.8 2.4 0.095 12.3 2.4 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Aminotran_1_2 PF00155.21 PSC68284.1 - 2.2e-71 240.9 0.0 2.9e-71 240.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 PSC68284.1 - 6.4e-08 32.3 0.0 1e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 PSC68284.1 - 0.0038 16.2 0.0 0.0061 15.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V 2OG-FeII_Oxy PF03171.20 PSC68284.1 - 0.13 12.8 0.0 0.24 11.9 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Hist_deacetyl PF00850.19 PSC68285.1 - 2.7e-72 243.9 0.0 5.1e-72 242.9 0.0 1.5 1 0 0 1 1 1 1 Histone deacetylase domain DnaJ PF00226.31 PSC68285.1 - 1.2e-17 63.7 0.1 2.5e-17 62.7 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain TPR_1 PF00515.28 PSC68285.1 - 2.7e-08 33.3 4.1 0.0013 18.5 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat KH_1 PF00013.29 PSC68285.1 - 2.8e-08 33.5 0.2 8.6e-08 31.9 0.2 1.8 1 1 0 1 1 1 1 KH domain TPR_2 PF07719.17 PSC68285.1 - 6.3e-07 29.0 8.6 0.0069 16.4 0.1 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 PSC68285.1 - 0.0036 17.0 0.3 1.6 8.5 0.1 3.4 3 0 0 3 3 3 1 TPR repeat TPR_12 PF13424.6 PSC68285.1 - 0.0081 16.4 1.9 0.0081 16.4 1.9 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 PSC68285.1 - 0.043 14.5 0.6 0.043 14.5 0.6 7.6 8 1 1 9 9 4 0 Tetratricopeptide repeat KH_2 PF07650.17 PSC68285.1 - 0.11 12.3 0.4 0.22 11.3 0.4 1.5 1 0 0 1 1 1 0 KH domain TPR_17 PF13431.6 PSC68285.1 - 0.11 12.9 0.5 0.47 11.0 0.1 2.3 2 0 0 2 2 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 PSC68285.1 - 0.18 12.1 4.0 13 6.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 PSC68285.1 - 0.2 11.6 5.6 6.1 6.9 0.5 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 PSC68285.1 - 0.34 11.1 11.4 0.13 12.4 1.0 3.7 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 PSC68285.1 - 2.5 8.9 6.0 6.6 7.6 0.1 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat Mur_ligase_M PF08245.12 PSC68286.1 - 3.1e-28 99.1 0.0 5.5e-28 98.3 0.0 1.3 1 0 0 1 1 1 1 Mur ligase middle domain NCBP3 PF10309.9 PSC68286.1 - 9.1e-17 60.7 0.0 2.2e-16 59.4 0.0 1.6 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 Mur_ligase_C PF02875.21 PSC68286.1 - 3.1e-12 46.6 0.0 1.1e-11 44.8 0.0 2.1 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain zf-MYND PF01753.18 PSC68286.1 - 1.2e-07 31.7 13.8 2.5e-07 30.7 13.8 1.6 1 0 0 1 1 1 1 MYND finger Mur_ligase PF01225.25 PSC68286.1 - 0.0027 18.0 0.0 0.015 15.6 0.0 2.3 2 0 0 2 2 2 1 Mur ligase family, catalytic domain RNA_bind PF08675.11 PSC68286.1 - 0.01 15.9 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 1 RNA binding domain SpoIIIAH PF12685.7 PSC68286.1 - 0.19 11.6 5.2 0.44 10.3 5.2 1.5 1 0 0 1 1 1 0 SpoIIIAH-like protein Nop14 PF04147.12 PSC68286.1 - 0.34 9.1 19.0 0.63 8.2 19.0 1.3 1 0 0 1 1 1 0 Nop14-like family CPSF100_C PF13299.6 PSC68286.1 - 0.4 10.8 4.0 1.3 9.2 4.0 1.8 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Myc_N PF01056.18 PSC68286.1 - 2 8.2 6.8 4.1 7.2 6.8 1.5 1 0 0 1 1 1 0 Myc amino-terminal region NUDIX PF00293.28 PSC68287.1 - 2.6e-11 43.7 0.0 3.4e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 PSC68287.1 - 0.16 12.0 0.1 0.29 11.2 0.1 1.7 1 1 0 1 1 1 0 NUDIX domain Cation_efflux PF01545.21 PSC68288.1 - 5.2e-37 127.5 32.5 1.1e-36 126.5 32.5 1.5 1 1 0 1 1 1 1 Cation efflux family TMEM107 PF14995.6 PSC68288.1 - 0.024 15.1 0.2 0.07 13.6 0.2 1.8 1 0 0 1 1 1 0 Transmembrane protein Oxidored_q5_N PF01059.17 PSC68288.1 - 0.19 11.8 0.7 0.41 10.8 0.7 1.6 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus RseC_MucC PF04246.12 PSC68288.1 - 0.77 9.7 4.6 0.43 10.5 0.4 2.4 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC DUF5518 PF17647.1 PSC68288.1 - 2 8.6 18.4 14 5.8 15.2 3.1 2 1 0 2 2 2 0 Family of unknown function (DUF5518) S1 PF00575.23 PSC68289.1 - 3.2e-08 33.8 0.0 4.9e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain WD-3 PF09765.9 PSC68290.1 - 1.3e-62 211.7 0.0 1.7e-62 211.4 0.0 1.1 1 0 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 PSC68290.1 - 2e-28 98.4 0.5 2.9e-28 97.8 0.5 1.2 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 PSC68290.1 - 0.0015 18.8 5.1 0.0063 16.8 5.1 2.0 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PSC68290.1 - 0.0022 18.2 0.9 0.0053 17.0 0.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 PSC68290.1 - 0.13 12.4 2.1 0.39 10.8 2.1 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H PF13771.6 PSC68290.1 - 0.14 12.5 0.1 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD PF00628.29 PSC68290.1 - 0.35 10.8 1.6 0.66 9.9 1.6 1.5 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 PSC68290.1 - 0.56 10.4 3.5 0.31 11.2 0.5 2.1 2 0 0 2 2 2 0 RING-variant domain Peptidase_S10 PF00450.22 PSC68291.1 - 6.3e-120 401.4 0.0 1e-119 400.7 0.0 1.3 1 1 0 1 1 1 1 Serine carboxypeptidase Patatin PF01734.22 PSC68291.1 - 8.3e-12 45.7 2.7 1.2e-11 45.2 0.8 2.3 2 1 0 2 2 2 1 Patatin-like phospholipase RskA PF10099.9 PSC68291.1 - 0.0011 19.3 7.0 0.021 15.1 0.4 3.2 3 0 0 3 3 3 2 Anti-sigma-K factor rskA Abhydrolase_1 PF00561.20 PSC68291.1 - 0.0082 15.8 0.1 5.1 6.7 0.0 2.7 2 0 0 2 2 2 2 alpha/beta hydrolase fold Ribosomal_60s PF00428.19 PSC68291.1 - 0.022 15.3 0.1 0.022 15.3 0.1 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein eIF-5_eIF-2B PF01873.17 PSC68292.1 - 3.2e-37 127.0 0.1 4.8e-37 126.4 0.1 1.2 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Daxx PF03344.15 PSC68292.1 - 0.015 15.4 0.0 0.035 14.2 0.0 1.7 1 0 0 1 1 1 0 Daxx N-terminal Rassf1C-interacting domain XG_FTase PF03254.13 PSC68293.1 - 0.15 10.6 0.0 0.36 9.4 0.0 1.6 2 0 0 2 2 2 0 Xyloglucan fucosyltransferase XG_FTase PF03254.13 PSC68294.1 - 0.15 10.6 0.0 0.36 9.4 0.0 1.6 2 0 0 2 2 2 0 Xyloglucan fucosyltransferase Kelch_4 PF13418.6 PSC68295.1 - 2e-39 133.3 15.3 2.8e-08 33.6 0.1 7.1 5 2 2 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.25 PSC68295.1 - 3.9e-37 125.6 4.3 4.2e-08 32.7 0.0 5.9 5 1 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 PSC68295.1 - 1e-36 124.5 16.3 1e-08 35.3 0.2 7.3 7 0 0 7 7 7 7 Galactose oxidase, central domain Kelch_6 PF13964.6 PSC68295.1 - 9.7e-32 108.2 1.3 3.3e-07 30.4 0.0 6.0 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.6 PSC68295.1 - 8.9e-21 73.4 5.5 6.5e-06 26.0 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 PSC68295.1 - 5.8e-16 57.8 6.3 0.00032 20.6 0.0 6.0 6 0 0 6 6 6 5 Kelch motif Mito_carr PF00153.27 PSC68296.1 - 1.9e-57 191.2 4.7 5e-23 80.8 0.0 3.4 3 1 0 3 3 3 3 Mitochondrial carrier protein YtxH PF12732.7 PSC68296.1 - 0.12 12.9 0.1 0.12 12.9 0.1 2.2 3 0 0 3 3 3 0 YtxH-like protein Serine_protease PF18405.1 PSC68296.1 - 0.14 11.3 0.5 5.7 6.0 0.0 2.4 2 1 0 2 2 2 0 Gammaproteobacterial serine protease C2 PF00168.30 PSC68297.1 - 4.9e-10 39.6 0.0 7e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 C2 domain Ysc84 PF04366.12 PSC68298.1 - 5e-08 32.7 0.0 3.5e-06 26.8 0.0 3.1 3 1 0 3 3 3 1 Las17-binding protein actin regulator DUF4723 PF15851.5 PSC68298.1 - 0.015 15.4 0.1 17 5.7 0.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4723) CBM_1 PF00734.18 PSC68298.1 - 8.9 6.4 11.4 18 5.4 2.1 2.7 2 0 0 2 2 2 0 Fungal cellulose binding domain Glyco_transf_24 PF18404.1 PSC68300.1 - 2.1e-143 476.5 3.7 2.8e-143 476.1 3.7 1.1 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 PSC68300.1 - 7.5e-39 134.2 0.0 1.1e-37 130.4 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 PSC68300.1 - 2.6e-27 95.9 0.0 7.6e-27 94.4 0.0 1.8 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 PSC68300.1 - 3.8e-23 81.9 0.3 1.5e-22 80.0 0.1 2.0 2 0 0 2 2 2 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 PSC68300.1 - 9.8e-23 80.4 0.0 1.8e-22 79.5 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_15 PF18403.1 PSC68300.1 - 2.8e-20 73.2 0.0 1.4e-19 70.9 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 PSC68300.1 - 4.9e-06 26.3 0.6 8e-06 25.6 0.6 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 SnoaL PF07366.12 PSC68301.1 - 2.5e-13 49.9 0.2 3.2e-09 36.6 0.1 2.3 2 0 0 2 2 2 2 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 PSC68301.1 - 1.1e-12 48.4 0.2 1.2e-07 32.3 0.3 2.4 2 0 0 2 2 2 2 SnoaL-like domain Foie-gras_1 PF11817.8 PSC68301.1 - 0.0096 15.5 0.5 0.016 14.8 0.5 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 SRP68 PF16969.5 PSC68303.1 - 4.6e-11 42.4 0.1 6.2e-11 42.0 0.1 1.1 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 Sporozoite_P67 PF05642.11 PSC68303.1 - 3 5.8 9.8 3.4 5.7 9.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Glyco_hydro_46 PF01374.18 PSC68304.1 - 1.9e-52 177.9 0.0 2.4e-52 177.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 PAN_4 PF14295.6 PSC68304.1 - 4.7e-08 32.8 0.8 4.7e-08 32.8 0.8 2.2 2 0 0 2 2 2 1 PAN domain PAN_1 PF00024.26 PSC68304.1 - 1.7e-06 27.9 0.3 3.7e-06 26.8 0.3 1.5 1 0 0 1 1 1 1 PAN domain Chitin_bind_1 PF00187.19 PSC68304.1 - 6e-05 23.4 12.2 6e-05 23.4 12.2 3.3 3 0 0 3 3 3 1 Chitin recognition protein UQ_con PF00179.26 PSC68305.1 - 1.6e-47 160.7 0.0 1.8e-47 160.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 PSC68305.1 - 0.0055 16.6 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 UEV domain Prok-E2_B PF14461.6 PSC68305.1 - 0.0059 16.3 0.0 0.0075 16.0 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 PSC68305.1 - 0.1 12.9 0.1 0.18 12.1 0.1 1.6 1 1 0 1 1 1 0 RWD domain Histone PF00125.24 PSC68309.1 - 2.9e-54 183.0 1.9 3.2e-54 182.8 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 PSC68309.1 - 0.00013 22.5 1.7 0.00016 22.2 1.7 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 PSC68309.1 - 0.00045 20.5 0.0 0.00069 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 PSC68309.1 - 0.00049 20.2 0.5 0.00074 19.6 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 PSC68309.1 - 0.0052 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PSC68309.1 - 0.016 15.3 0.1 0.031 14.3 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit PUB PF09409.10 PSC68310.1 - 7.1e-17 61.1 0.0 1.7e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 PUB domain CENP-T_C PF15511.6 PSC68310.1 - 2.7e-07 30.7 0.0 6.9e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold UBA PF00627.31 PSC68310.1 - 1.9e-06 27.6 0.0 5.4e-06 26.2 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain TAF PF02969.17 PSC68310.1 - 0.00079 19.5 0.2 0.0059 16.7 0.0 2.5 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 PSC68310.1 - 0.0016 18.8 0.0 0.004 17.5 0.0 1.7 1 0 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.13 PSC68310.1 - 0.01 15.8 0.0 0.025 14.6 0.0 1.6 1 0 0 1 1 1 0 Bromodomain associated CBFD_NFYB_HMF PF00808.23 PSC68310.1 - 0.011 16.0 0.0 0.037 14.3 0.0 2.0 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-C2H2_2 PF12756.7 PSC68310.1 - 0.014 15.7 3.6 0.86 10.0 0.0 2.4 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 PSC68310.1 - 0.014 15.8 2.0 3.1 8.3 0.5 2.4 2 0 0 2 2 2 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PSC68310.1 - 0.13 12.6 1.2 1.2 9.5 0.3 2.2 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2_4 PF13894.6 PSC68310.1 - 0.26 12.2 2.2 14 6.9 0.6 2.7 3 0 0 3 3 2 0 C2H2-type zinc finger DZR PF12773.7 PSC68310.1 - 0.6 10.2 2.8 1.3 9.1 2.8 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-C2H2_6 PF13912.6 PSC68310.1 - 2.6 8.1 3.9 25 5.0 0.1 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger MCM3AP_GANP PF16769.5 PSC68310.1 - 10 4.3 9.0 14 3.8 9.0 1.1 1 0 0 1 1 1 0 MCM3AP domain of GANP DUF2477 PF10631.9 PSC68311.1 - 0.052 14.2 5.0 0.14 12.8 5.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) DUF2828 PF11443.8 PSC68312.1 - 0.0033 15.6 2.4 0.0054 14.9 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF2828) TFIIA PF03153.13 PSC68312.1 - 0.0068 16.5 22.1 0.012 15.6 22.1 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 PSC68312.1 - 2.4 8.1 3.9 4.3 7.3 3.9 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1180 PF06679.12 PSC68312.1 - 5.1 7.5 7.9 26 5.2 7.9 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Presenilin PF01080.17 PSC68312.1 - 6.6 5.4 11.3 10 4.7 11.3 1.2 1 0 0 1 1 1 0 Presenilin CCDC53 PF10152.9 PSC68312.1 - 7 7.1 13.2 0.91 9.9 8.2 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex 2OG-FeII_Oxy_3 PF13640.6 PSC68313.1 - 1.7e-11 44.9 0.2 1.1e-10 42.3 0.2 2.2 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Ank_2 PF12796.7 PSC68314.1 - 3.3e-09 37.2 0.8 9.1e-09 35.8 0.8 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC68314.1 - 3.6e-09 37.0 0.5 7.6e-07 29.6 0.1 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC68314.1 - 1.5e-08 34.7 0.6 4.6e-08 33.2 0.3 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC68314.1 - 5.7e-06 26.3 2.8 0.0019 18.5 0.2 3.6 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 PSC68314.1 - 0.00014 22.2 6.5 0.0067 16.8 0.5 3.6 2 1 1 3 3 3 2 Ankyrin repeat S1 PF00575.23 PSC68315.1 - 2e-13 50.5 0.0 3.6e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 S1 RNA binding domain SHS2_Rpb7-N PF03876.17 PSC68315.1 - 3.6e-12 46.5 0.0 6.1e-12 45.7 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 Sec23_trunk PF04811.15 PSC68317.1 - 1.3e-57 195.2 0.0 1.8e-57 194.7 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 PSC68317.1 - 5.2e-18 65.6 0.0 1.1e-17 64.6 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 PSC68317.1 - 6.6e-18 64.4 0.1 1.2e-17 63.6 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 PSC68317.1 - 8.9e-15 54.5 2.3 1.6e-14 53.7 2.3 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 PSC68317.1 - 6.1e-06 26.0 0.0 1.7e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat RVT_1 PF00078.27 PSC68320.1 - 2.4e-26 92.6 0.0 3.9e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 PSC68320.1 - 4.4e-21 74.8 0.0 8.5e-21 73.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 PSC68320.1 - 7.4e-09 35.8 0.0 1.6e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Histone_H2A_C PF16211.5 PSC68321.1 - 1.1e-20 73.1 1.3 2.1e-20 72.1 1.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 PSC68321.1 - 2.1e-15 57.2 0.0 2.6e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC68321.1 - 1.5e-05 25.2 0.0 2.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PPR_2 PF13041.6 PSC68322.1 - 5e-39 132.3 0.0 1e-09 38.4 0.0 6.8 1 1 6 7 7 7 7 PPR repeat family PPR PF01535.20 PSC68322.1 - 5.9e-35 117.1 0.0 8.1e-05 22.6 0.0 7.8 8 0 0 8 8 7 7 PPR repeat PPR_3 PF13812.6 PSC68322.1 - 2.1e-30 104.5 0.0 1.7e-10 40.8 0.0 5.8 3 1 2 6 6 6 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 PSC68322.1 - 9.6e-24 82.8 0.0 0.00072 19.2 0.0 8.5 8 0 0 8 8 8 6 PPR repeat PPR_long PF17177.4 PSC68322.1 - 3.8e-22 78.7 1.2 1.5e-11 44.1 0.1 3.1 1 1 2 3 3 3 2 Pentacotripeptide-repeat region of PRORP Smr PF01713.21 PSC68322.1 - 1e-05 25.8 0.4 4.2e-05 23.8 0.2 2.2 2 0 0 2 2 2 1 Smr domain TPR_7 PF13176.6 PSC68322.1 - 8.9e-05 22.3 0.2 0.97 9.6 0.0 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF3368 PF11848.8 PSC68322.1 - 0.0084 15.9 0.0 3.3 7.6 0.0 4.2 5 0 0 5 5 5 1 Domain of unknown function (DUF3368) TPR_10 PF13374.6 PSC68322.1 - 0.049 13.5 1.1 0.67 9.9 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Wzy_C_2 PF11846.8 PSC68322.1 - 0.082 12.8 3.8 1.3 9.0 0.1 4.0 5 1 0 5 5 5 0 Virulence factor membrane-bound polymerase, C-terminal TPR_14 PF13428.6 PSC68322.1 - 0.3 12.0 35.0 6.5 7.8 0.0 9.1 4 3 6 10 10 9 0 Tetratricopeptide repeat TPR_2 PF07719.17 PSC68322.1 - 1.7 8.9 4.8 7.5 6.9 0.4 4.1 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 PSC68322.1 - 8.2 6.8 11.5 35 4.8 0.1 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat RRM_1 PF00076.22 PSC68323.1 - 1.9e-12 46.8 0.0 2.7e-12 46.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4407 PF14362.6 PSC68323.1 - 0.01 15.2 12.2 0.014 14.8 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Neur_chan_memb PF02932.16 PSC68323.1 - 0.86 9.6 5.0 1 9.4 5.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region VIT1 PF01988.19 PSC68323.1 - 1.9 8.3 9.4 2.7 7.8 9.4 1.2 1 0 0 1 1 1 0 VIT family eIF-3_zeta PF05091.12 PSC68323.1 - 3.3 6.6 13.0 4.3 6.2 13.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hid1 PF12722.7 PSC68323.1 - 3.7 5.5 9.4 4.5 5.3 9.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SprA-related PF12118.8 PSC68323.1 - 6.9 5.7 27.9 8.8 5.4 27.9 1.1 1 0 0 1 1 1 0 SprA-related family Ctr PF04145.15 PSC68323.1 - 7.1 7.2 5.6 11 6.6 5.6 1.4 1 0 0 1 1 1 0 Ctr copper transporter family SLC12 PF03522.15 PSC68323.1 - 7.8 5.4 11.4 9.8 5.1 11.4 1.1 1 0 0 1 1 1 0 Solute carrier family 12 SUIM_assoc PF16619.5 PSC68324.1 - 0.00039 20.4 10.5 0.00039 20.4 10.5 2.7 2 1 0 2 2 1 1 Unstructured region C-term to UIM in Ataxin3 ASD2 PF08687.11 PSC68324.1 - 0.0036 16.9 9.2 0.0042 16.7 9.2 1.1 1 0 0 1 1 1 1 Apx/Shroom domain ASD2 Ribonuc_L-PSP PF01042.21 PSC68324.1 - 0.043 13.8 1.0 0.043 13.8 1.0 1.8 2 0 0 2 2 1 0 Endoribonuclease L-PSP VIR_N PF15912.5 PSC68324.1 - 0.28 10.7 10.8 0.33 10.5 10.8 1.0 1 0 0 1 1 1 0 Virilizer, N-terminal Neur_chan_memb PF02932.16 PSC68324.1 - 0.28 11.2 7.0 0.35 10.9 7.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 PSC68324.1 - 0.33 9.0 10.1 0.35 9.0 10.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.9 PSC68324.1 - 0.39 8.9 22.6 0.41 8.9 22.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 PSC68324.1 - 0.61 7.1 11.5 0.64 7.1 11.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF4407 PF14362.6 PSC68324.1 - 0.76 9.1 12.2 1 8.7 12.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BORG_CEP PF14957.6 PSC68324.1 - 0.8 10.9 7.1 1 10.5 7.1 1.3 1 0 0 1 1 1 0 Cdc42 effector Thymidylate_kin PF02223.17 PSC68324.1 - 0.88 9.2 6.7 0.37 10.4 0.1 2.0 2 0 0 2 2 2 0 Thymidylate kinase DUF4748 PF15932.5 PSC68324.1 - 3.4 7.5 0.0 3.4 7.5 0.0 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF4748) SARAF PF06682.12 PSC68324.1 - 3.7 7.1 17.0 4.7 6.8 17.0 1.1 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis RR_TM4-6 PF06459.12 PSC68324.1 - 4 7.2 15.8 5.1 6.8 15.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 IER PF05760.12 PSC68324.1 - 5.6 7.2 20.2 7 6.9 20.2 1.1 1 0 0 1 1 1 0 Immediate early response protein (IER) Presenilin PF01080.17 PSC68324.1 - 5.7 5.6 19.5 7.1 5.3 19.5 1.0 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 PSC68324.1 - 7 4.8 11.9 8.6 4.5 11.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4569 PF15133.6 PSC68324.1 - 9.6 5.8 15.7 12 5.5 15.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) RRM_1 PF00076.22 PSC68325.1 - 3.3e-15 55.7 0.0 5.1e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) KH_1 PF00013.29 PSC68326.1 - 1.6e-41 139.9 0.7 1.4e-14 53.6 0.8 3.7 3 0 0 3 3 3 3 KH domain KH_2 PF07650.17 PSC68326.1 - 4.7e-10 39.2 0.9 0.015 15.1 0.2 3.7 3 0 0 3 3 3 3 KH domain MULE PF10551.9 PSC68326.1 - 1.3e-09 38.3 0.0 2.5e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain G-patch PF01585.23 PSC68326.1 - 4.2e-09 36.2 3.9 2.3e-08 33.8 3.3 2.4 2 0 0 2 2 2 1 G-patch domain KH_4 PF13083.6 PSC68326.1 - 1.2e-08 34.7 2.5 0.029 14.2 0.7 3.8 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 PSC68326.1 - 0.061 13.4 5.8 3.2 7.9 1.2 3.4 3 0 0 3 3 3 0 NusA-like KH domain RPN6_N PF18055.1 PSC68326.1 - 0.077 13.4 0.3 0.17 12.2 0.3 1.5 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN6 N-terminal domain DUF5616 PF18481.1 PSC68326.1 - 0.22 11.8 0.0 1.4 9.3 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5616) DUF677 PF05055.12 PSC68326.1 - 0.51 9.2 1.6 0.9 8.4 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DJ-1_PfpI PF01965.24 PSC68327.1 - 9.3e-47 158.9 0.4 1.1e-46 158.7 0.4 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family MauJ PF17419.2 PSC68327.1 - 0.097 12.1 0.1 0.17 11.3 0.1 1.3 1 0 0 1 1 1 0 Methylamine utilization protein MauJ Ion_trans PF00520.31 PSC68328.1 - 1.7e-10 40.6 1.6 2.2e-10 40.2 1.6 1.1 1 0 0 1 1 1 1 Ion transport protein DUF5391 PF17369.2 PSC68328.1 - 0.084 12.9 0.5 0.14 12.2 0.5 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5391) Histone_H2A_C PF16211.5 PSC68329.1 - 1.1e-20 73.1 1.3 2.1e-20 72.1 1.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 PSC68329.1 - 2.1e-15 57.2 0.0 2.6e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC68329.1 - 1.5e-05 25.2 0.0 2.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Herpes_UL52 PF03121.15 PSC68330.1 - 1.1e-05 25.3 0.0 2.2e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase Kelch_2 PF07646.15 PSC68330.1 - 0.13 12.2 0.1 13 6.0 0.1 2.8 2 0 0 2 2 2 0 Kelch motif Histone PF00125.24 PSC68331.1 - 1.2e-15 58.0 0.0 1.5e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC68331.1 - 0.0078 16.5 0.1 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 PSC68331.1 - 0.053 13.2 0.5 2.8 7.6 0.0 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain DnaJ PF00226.31 PSC68331.1 - 0.058 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain TFIID_20kDa PF03847.13 PSC68331.1 - 0.2 12.2 0.0 0.33 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A EMP70 PF02990.16 PSC68332.1 - 2.5e-220 732.5 4.8 3.5e-220 732.1 4.8 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 MFS_1 PF07690.16 PSC68332.1 - 7.4 5.4 43.5 0.0063 15.5 14.6 2.8 1 1 1 2 2 2 0 Major Facilitator Superfamily tRNA_bind PF01588.20 PSC68333.1 - 2.7e-31 107.5 0.0 4.4e-31 106.8 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain Histone PF00125.24 PSC68334.1 - 2.9e-54 183.0 1.9 3.2e-54 182.8 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 PSC68334.1 - 0.00013 22.5 1.7 0.00016 22.2 1.7 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 PSC68334.1 - 0.00045 20.5 0.0 0.00069 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 PSC68334.1 - 0.00049 20.2 0.5 0.00074 19.6 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 PSC68334.1 - 0.0052 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PSC68334.1 - 0.016 15.3 0.1 0.031 14.3 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit PfkB PF00294.24 PSC68335.1 - 2.6e-40 138.6 0.2 9.5e-40 136.8 0.2 1.9 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Lysine_decarbox PF03641.14 PSC68335.1 - 1.8e-23 83.1 0.0 4.2e-23 81.9 0.0 1.7 1 0 0 1 1 1 1 Possible lysine decarboxylase G-patch PF01585.23 PSC68335.1 - 2e-12 46.8 0.0 5.3e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 G-patch domain LDcluster4 PF18306.1 PSC68335.1 - 0.0089 15.6 0.0 0.0089 15.6 0.0 2.0 2 0 0 2 2 2 1 SLOG cluster4 family CENP-T_C PF15511.6 PSC68336.1 - 2e-08 34.3 0.1 2.5e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PSC68336.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 PSC68336.1 - 0.00022 21.3 0.1 0.00031 20.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 PSC68336.1 - 0.0011 18.9 0.1 0.0017 18.4 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 PSC68336.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PSC68336.1 - 0.0015 18.9 0.1 0.0017 18.8 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 PSC68336.1 - 0.033 14.3 0.0 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Yippee-Mis18 PF03226.14 PSC68338.1 - 2.7e-16 59.7 0.3 4e-16 59.1 0.3 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Nucleotid_trans PF03407.16 PSC68339.1 - 0.01 15.9 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 PSC68339.1 - 0.13 11.9 0.0 0.42 10.3 0.0 1.6 2 0 0 2 2 2 0 galactosyl transferase GMA12/MNN10 family PIG-P PF08510.12 PSC68340.1 - 2.9e-28 98.2 0.5 3.6e-28 97.9 0.5 1.1 1 0 0 1 1 1 1 PIG-P DPM2 PF07297.12 PSC68340.1 - 0.052 13.9 6.5 0.09 13.1 6.5 1.3 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) DUF997 PF06196.12 PSC68340.1 - 3.1 7.9 10.3 5.1 7.2 10.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF997) PSI_PSAK PF01241.18 PSC68341.1 - 4.6e-15 55.4 0.3 1.2e-14 54.0 0.3 1.8 1 0 0 1 1 1 1 Photosystem I psaG / psaK ALMT PF11744.8 PSC68341.1 - 1.8e-09 37.0 27.2 1.3e-08 34.2 10.6 2.8 2 1 1 3 3 3 2 Aluminium activated malate transporter FUSC PF04632.12 PSC68341.1 - 4.9e-09 35.3 26.7 4.9e-09 35.3 26.7 5.3 3 3 2 6 6 6 1 Fusaric acid resistance protein family FUSC_2 PF13515.6 PSC68341.1 - 1.1e-06 28.8 11.6 1.1e-06 28.8 11.6 4.0 3 1 1 4 4 4 3 Fusaric acid resistance protein-like HSP70 PF00012.20 PSC68342.1 - 1.6e-92 310.6 0.0 5.8e-92 308.8 0.0 1.7 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PSC68342.1 - 4.8e-05 22.3 0.0 0.00035 19.5 0.0 2.2 1 1 0 1 1 1 1 MreB/Mbl protein Mito_fiss_reg PF05308.11 PSC68342.1 - 0.079 13.0 3.3 0.45 10.6 0.9 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator CAP_N PF01213.19 PSC68342.1 - 0.68 9.4 13.4 3.4 7.1 0.5 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal HSP70 PF00012.20 PSC68343.1 - 1.8e-88 297.3 0.0 6.6e-88 295.4 0.0 1.8 1 1 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PSC68343.1 - 5.1e-05 22.2 0.0 0.00035 19.5 0.0 2.1 1 1 0 1 1 1 1 MreB/Mbl protein Mito_fiss_reg PF05308.11 PSC68343.1 - 0.079 13.0 3.2 0.46 10.5 0.9 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator CAP_N PF01213.19 PSC68343.1 - 0.66 9.4 13.3 3.4 7.1 0.5 2.4 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Sulfotransfer_2 PF03567.14 PSC68344.1 - 8.8e-05 22.5 0.1 0.00081 19.4 0.1 2.3 1 1 0 1 1 1 1 Sulfotransferase family Barwin PF00967.17 PSC68344.1 - 0.065 13.1 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 Barwin family LSM PF01423.22 PSC68346.1 - 3.1e-14 52.4 0.1 3.8e-14 52.1 0.1 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 PSC68346.1 - 6.9e-05 22.9 0.1 8e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF1256 PF06866.11 PSC68346.1 - 0.0079 15.6 0.1 0.0088 15.5 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1256) LSM14 PF12701.7 PSC68346.1 - 0.023 14.8 0.0 0.026 14.6 0.0 1.2 1 0 0 1 1 1 0 Scd6-like Sm domain PQ-loop PF04193.14 PSC68347.1 - 1.5e-18 66.3 5.7 1.5e-08 34.2 0.1 3.2 3 0 0 3 3 3 2 PQ loop repeat Rhodanese PF00581.20 PSC68348.1 - 1.9e-11 44.4 0.2 9.3e-11 42.2 0.2 2.1 1 1 0 1 1 1 1 Rhodanese-like domain ANAPC16 PF17256.2 PSC68348.1 - 0.011 16.1 0.1 0.092 13.1 0.1 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex, subunit 16 Ammonium_transp PF00909.21 PSC68349.1 - 3.9e-106 355.1 31.1 3.2e-105 352.1 31.1 2.0 1 1 0 1 1 1 1 Ammonium Transporter Family HA PF03457.14 PSC68349.1 - 8.4e-22 77.3 10.4 2.6e-11 43.7 0.3 3.4 3 0 0 3 3 3 3 Helicase associated domain Tetraspanin PF00335.20 PSC68350.1 - 1.9e-05 24.5 7.2 4.6e-05 23.3 7.2 1.5 1 1 0 1 1 1 1 Tetraspanin family SUR7 PF06687.12 PSC68350.1 - 0.029 14.0 1.9 0.091 12.4 2.1 1.7 2 0 0 2 2 2 0 SUR7/PalI family DUF4199 PF13858.6 PSC68350.1 - 0.18 12.2 1.6 0.75 10.2 1.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) p450 PF00067.22 PSC68351.1 - 1.9e-62 211.5 0.0 2.4e-62 211.2 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 RCC1 PF00415.18 PSC68352.1 - 8.1e-52 173.7 25.0 2.3e-13 50.5 0.2 6.6 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PSC68352.1 - 1.6e-37 126.6 45.1 1.9e-11 43.4 0.7 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat zf-C2HC5 PF06221.13 PSC68353.1 - 0.068 13.2 1.5 0.18 11.8 1.5 1.6 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type ADK PF00406.22 PSC68355.1 - 6.1e-57 192.0 0.0 8.3e-57 191.5 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 PSC68355.1 - 2.1e-20 73.5 0.0 6.1e-20 72.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 PSC68355.1 - 9.9e-17 60.6 0.0 1.8e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 PSC68355.1 - 0.024 14.8 0.0 0.058 13.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain Sigma54_activ_2 PF14532.6 PSC68355.1 - 0.15 12.2 0.0 0.3 11.2 0.0 1.5 2 0 0 2 2 2 0 Sigma-54 interaction domain zf-CCCH PF00642.24 PSC68356.1 - 3.6e-16 58.6 14.1 1.3e-08 34.5 2.0 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PSC68356.1 - 2.5e-08 33.7 15.7 3.3e-05 23.8 4.0 2.4 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 PSC68356.1 - 6e-06 25.9 2.5 6e-06 25.9 2.5 2.6 2 1 0 2 2 2 1 CCCH-type zinc finger Torus PF16131.5 PSC68356.1 - 0.019 15.7 9.4 0.039 14.6 0.2 2.3 2 0 0 2 2 2 0 Torus domain zf-CCCH_2 PF14608.6 PSC68356.1 - 0.037 14.5 1.1 0.037 14.5 1.1 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DDE_Tnp_1_6 PF13751.6 PSC68356.1 - 0.054 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain AA_permease_2 PF13520.6 PSC68357.1 - 2.7e-74 250.5 67.1 1.5e-41 142.6 26.8 3.5 2 2 0 3 3 3 2 Amino acid permease AA_permease PF00324.21 PSC68357.1 - 1.7e-38 132.4 63.7 1.4e-21 76.6 22.8 3.5 3 0 0 3 3 3 2 Amino acid permease DUF4579 PF15158.6 PSC68357.1 - 2.1 8.0 7.9 12 5.6 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4579) Pro_isomerase PF00160.21 PSC68358.1 - 1e-45 155.8 0.0 2.5e-45 154.6 0.0 1.7 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SYF2 PF08231.12 PSC68358.1 - 7.1e-35 120.8 6.5 7.1e-35 120.8 6.5 2.5 2 1 1 3 3 3 1 SYF2 splicing factor Mt_ATP_synt PF15704.5 PSC68360.1 - 7.3e-50 169.5 0.3 9e-50 169.2 0.3 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase subunit HrpB2 PF09487.10 PSC68360.1 - 0.091 13.2 0.0 0.17 12.3 0.0 1.6 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB2) 60KD_IMP PF02096.20 PSC68360.1 - 0.19 11.6 0.2 4 7.3 0.0 2.4 2 1 1 3 3 3 0 60Kd inner membrane protein Histone PF00125.24 PSC68361.1 - 2.9e-54 183.0 1.9 3.2e-54 182.8 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 PSC68361.1 - 0.00013 22.5 1.7 0.00016 22.2 1.7 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 PSC68361.1 - 0.00045 20.5 0.0 0.00069 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 PSC68361.1 - 0.00049 20.2 0.5 0.00074 19.6 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 PSC68361.1 - 0.0052 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PSC68361.1 - 0.016 15.3 0.1 0.031 14.3 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit DUF2207 PF09972.9 PSC68362.1 - 0.08 11.7 0.0 0.12 11.1 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) XK-related PF09815.9 PSC68362.1 - 0.08 12.0 0.2 0.13 11.3 0.2 1.2 1 0 0 1 1 1 0 XK-related protein EphA2_TM PF14575.6 PSC68362.1 - 0.089 13.7 0.9 0.25 12.3 0.0 2.2 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TMIE PF16038.5 PSC68362.1 - 0.12 12.2 0.1 0.29 11.0 0.1 1.5 1 0 0 1 1 1 0 TMIE protein Collectrin PF16959.5 PSC68362.1 - 0.15 11.8 2.5 0.25 11.1 2.5 1.3 1 0 0 1 1 1 0 Renal amino acid transporter LapA_dom PF06305.11 PSC68362.1 - 2.5 8.0 8.2 0.072 12.9 0.4 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain OAD_gamma PF04277.13 PSC68362.1 - 3.7 8.2 0.0 3.7 8.2 0.0 4.1 5 0 0 5 5 5 0 Oxaloacetate decarboxylase, gamma chain CENP-T_C PF15511.6 PSC68363.1 - 2e-08 34.3 0.1 2.5e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PSC68363.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 PSC68363.1 - 0.00022 21.3 0.1 0.00031 20.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 PSC68363.1 - 0.0011 18.9 0.1 0.0017 18.4 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 PSC68363.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PSC68363.1 - 0.0015 18.9 0.1 0.0017 18.8 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 PSC68363.1 - 0.033 14.3 0.0 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Sedlin_N PF04628.13 PSC68364.1 - 1.4e-36 125.5 0.0 1.9e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Peroxin-3 PF04882.12 PSC68364.1 - 3.3e-17 62.6 0.0 1.1e-12 47.7 0.0 3.2 1 1 1 2 2 2 2 Peroxin-3 Sybindin PF04099.12 PSC68364.1 - 3.3e-07 30.3 0.0 5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Sybindin-like family Histone PF00125.24 PSC68365.1 - 1.2e-15 58.0 0.0 1.5e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC68365.1 - 0.0078 16.5 0.1 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 PSC68365.1 - 0.053 13.2 0.5 2.8 7.6 0.0 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain DnaJ PF00226.31 PSC68365.1 - 0.058 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain TFIID_20kDa PF03847.13 PSC68365.1 - 0.2 12.2 0.0 0.33 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A SRP40_C PF05022.12 PSC68366.1 - 1.3e-23 83.6 3.0 1.3e-23 83.6 3.0 3.6 4 0 0 4 4 4 1 SRP40, C-terminal domain Fasciclin PF02469.22 PSC68366.1 - 1.4e-12 48.0 0.1 3.3e-12 46.7 0.0 1.7 2 0 0 2 2 2 1 Fasciclin domain Pollen_allerg_1 PF01357.21 PSC68366.1 - 4.7e-09 36.2 0.0 9.7e-09 35.1 0.0 1.4 1 0 0 1 1 1 1 Pollen allergen TFIIA PF03153.13 PSC68366.1 - 0.48 10.4 21.7 0.78 9.7 21.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ArgJ PF01960.18 PSC68367.1 - 4.9e-31 107.8 0.0 6.1e-30 104.2 0.0 2.0 1 1 0 1 1 1 1 ArgJ family FixQ PF05545.11 PSC68367.1 - 3.6 7.6 6.2 27 4.8 0.8 2.7 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Mito_carr PF00153.27 PSC68368.1 - 1.5e-52 175.5 5.6 4.9e-21 74.5 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PI3Ka PF00613.20 PSC68369.1 - 2.9e-56 189.8 0.0 4.4e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 PSC68369.1 - 5.7e-48 163.9 0.0 9.6e-45 153.3 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 PSC68369.1 - 4.1e-26 91.6 0.0 6.1e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DnaJ PF00226.31 PSC68370.1 - 4.8e-14 52.2 0.0 1.2e-13 51.0 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain DUF3752 PF12572.8 PSC68370.1 - 1.5e-11 45.0 0.9 1.5e-11 45.0 0.9 5.1 5 2 0 5 5 5 1 Protein of unknown function (DUF3752) T2SSF PF00482.23 PSC68370.1 - 0.29 11.1 4.2 0.75 9.8 0.1 2.8 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F RNase_PH PF01138.21 PSC68371.1 - 3.2e-35 121.5 4.3 5.7e-17 62.5 0.0 3.0 3 0 0 3 3 3 2 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PSC68371.1 - 2e-10 40.5 0.1 3.1e-06 27.1 0.0 2.9 2 1 0 2 2 2 2 3' exoribonuclease family, domain 2 S1 PF00575.23 PSC68371.1 - 5.2e-10 39.5 0.0 1e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain KH_1 PF00013.29 PSC68371.1 - 1.1e-09 38.0 0.0 2e-08 34.0 0.0 2.6 2 0 0 2 2 2 1 KH domain PNPase PF03726.14 PSC68371.1 - 1.9e-05 25.1 0.0 4.4e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Polyribonucleotide nucleotidyltransferase, RNA binding domain KH_2 PF07650.17 PSC68371.1 - 0.0048 16.7 0.0 0.0098 15.7 0.0 1.5 1 0 0 1 1 1 1 KH domain Barwin PF00967.17 PSC68371.1 - 0.016 15.1 0.1 0.061 13.2 0.1 2.1 1 0 0 1 1 1 0 Barwin family MitMem_reg PF13012.6 PSC68372.1 - 5.3e-37 126.7 0.2 8.8e-37 126.0 0.2 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 PSC68372.1 - 2.1e-31 108.3 0.3 7.1e-31 106.6 0.0 1.9 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DSBA PF01323.20 PSC68373.1 - 1.6e-16 60.7 0.0 1.6e-16 60.7 0.0 6.0 4 3 1 6 6 6 1 DSBA-like thioredoxin domain DUF948 PF06103.11 PSC68373.1 - 5.2 7.4 6.6 61 4.0 0.3 4.0 4 1 0 4 4 4 0 Bacterial protein of unknown function (DUF948) 14-3-3 PF00244.20 PSC68375.1 - 1.8e-105 351.3 3.7 2.1e-105 351.1 3.7 1.0 1 0 0 1 1 1 1 14-3-3 protein GED PF02212.18 PSC68375.1 - 0.033 14.3 2.9 0.17 12.1 0.3 2.6 2 1 0 2 2 2 0 Dynamin GTPase effector domain PhoU_div PF01865.16 PSC68375.1 - 0.047 13.0 3.0 0.64 9.3 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF47 TPR_19 PF14559.6 PSC68375.1 - 0.18 12.4 3.6 0.24 12.0 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat DnaJ PF00226.31 PSC68376.1 - 9.7e-20 70.5 0.0 1.4e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Abhydrolase_6 PF12697.7 PSC68377.1 - 4.7e-12 47.0 9.1 4.7e-12 47.0 9.1 4.3 3 1 1 4 4 4 2 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PSC68377.1 - 2.5e-08 33.9 0.2 0.00031 20.5 0.1 2.8 3 0 0 3 3 3 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC68377.1 - 3.2e-07 29.8 0.1 0.0006 19.2 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FGGY_C PF02782.16 PSC68377.1 - 0.00046 20.0 0.1 0.046 13.4 0.0 2.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Peptidase_S9 PF00326.21 PSC68377.1 - 0.072 12.5 0.0 0.17 11.3 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Abhydrolase_4 PF08386.10 PSC68377.1 - 0.086 13.0 0.0 0.33 11.1 0.0 2.0 1 0 0 1 1 1 0 TAP-like protein Hema_HEFG PF02710.14 PSC68377.1 - 0.22 11.7 0.2 2.3 8.4 0.1 2.4 2 1 1 3 3 3 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein Suf PF05843.14 PSC68377.1 - 2.2 8.2 5.4 3.7 7.5 5.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) dsDNA_bind PF01984.20 PSC68378.1 - 5.1e-34 116.9 13.7 5.9e-34 116.7 13.7 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain EF-1_beta_acid PF10587.9 PSC68378.1 - 0.16 12.5 0.5 0.16 12.5 0.5 3.2 3 1 0 3 3 3 0 Eukaryotic elongation factor 1 beta central acidic region dsDNA_bind PF01984.20 PSC68379.1 - 1.2e-31 109.2 13.7 1.2e-31 109.2 13.7 6.7 4 1 0 4 4 3 1 Double-stranded DNA-binding domain Kelch_4 PF13418.6 PSC68379.1 - 4.7e-31 106.5 0.7 7.5e-10 38.7 0.1 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 PSC68379.1 - 6.1e-27 93.3 8.4 1.6e-07 31.4 0.0 7.2 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 PSC68379.1 - 3.4e-18 65.2 0.0 6.1e-07 29.3 0.0 6.2 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 PSC68379.1 - 4.5e-17 61.7 0.1 2.7e-05 24.3 0.0 6.1 5 1 1 6 6 6 3 Kelch motif Cupin_2 PF07883.11 PSC68379.1 - 2.2e-14 52.9 0.4 1.8e-07 30.7 0.1 2.9 2 0 0 2 2 2 2 Cupin domain Kelch_1 PF01344.25 PSC68379.1 - 2.2e-14 52.8 0.0 0.017 14.7 0.0 6.0 5 0 0 5 5 5 4 Kelch motif Fea1 PF07692.11 PSC68379.1 - 2.9e-09 36.5 3.9 2.9e-09 36.5 3.9 1.9 2 0 0 2 2 1 1 Low iron-inducible periplasmic protein Cupin_3 PF05899.12 PSC68379.1 - 2.7e-06 27.0 0.0 7.2e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Kelch_2 PF07646.15 PSC68379.1 - 5.4e-06 26.2 0.0 2.6 8.2 0.0 4.9 4 0 0 4 4 4 2 Kelch motif AraC_binding PF02311.19 PSC68379.1 - 0.0073 16.2 14.0 0.016 15.1 0.0 3.8 4 1 0 4 4 3 2 AraC-like ligand binding domain Kelch_4 PF13418.6 PSC68380.1 - 2.1e-31 107.7 0.7 6.6e-10 38.8 0.1 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 PSC68380.1 - 3.3e-27 94.2 8.7 1.4e-07 31.6 0.0 7.2 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 PSC68380.1 - 1.7e-18 66.1 0.0 5.3e-07 29.5 0.0 6.2 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 PSC68380.1 - 2.1e-17 62.7 0.1 2.4e-05 24.5 0.0 6.3 5 1 1 6 6 6 3 Kelch motif Kelch_1 PF01344.25 PSC68380.1 - 1.1e-14 53.8 0.0 0.015 14.9 0.0 6.1 6 0 0 6 6 6 4 Kelch motif Cupin_2 PF07883.11 PSC68380.1 - 1.5e-14 53.4 0.4 1.6e-07 30.9 0.1 3.0 2 0 0 2 2 2 2 Cupin domain Fea1 PF07692.11 PSC68380.1 - 2.5e-09 36.7 3.9 2.5e-09 36.7 3.9 2.0 2 0 0 2 2 2 1 Low iron-inducible periplasmic protein Cupin_3 PF05899.12 PSC68380.1 - 2.3e-06 27.2 0.0 6.3e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Kelch_2 PF07646.15 PSC68380.1 - 3e-06 27.0 0.0 2.2 8.4 0.0 5.0 4 0 0 4 4 4 2 Kelch motif AraC_binding PF02311.19 PSC68380.1 - 0.011 15.7 15.1 0.014 15.3 0.0 3.9 4 1 0 4 4 4 0 AraC-like ligand binding domain Kelch_4 PF13418.6 PSC68381.1 - 2.1e-31 107.7 0.7 6.6e-10 38.8 0.1 6.7 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 PSC68381.1 - 3.3e-27 94.2 8.7 1.4e-07 31.6 0.0 7.2 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_5 PF13854.6 PSC68381.1 - 1.7e-18 66.1 0.0 5.3e-07 29.5 0.0 6.2 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 PSC68381.1 - 2.1e-17 62.7 0.1 2.4e-05 24.5 0.0 6.3 5 1 1 6 6 6 3 Kelch motif Kelch_1 PF01344.25 PSC68381.1 - 1.1e-14 53.8 0.0 0.015 14.9 0.0 6.1 6 0 0 6 6 6 4 Kelch motif Cupin_2 PF07883.11 PSC68381.1 - 1.5e-14 53.4 0.4 1.6e-07 30.9 0.1 3.0 2 0 0 2 2 2 2 Cupin domain Fea1 PF07692.11 PSC68381.1 - 2.5e-09 36.7 3.9 2.5e-09 36.7 3.9 2.0 2 0 0 2 2 2 1 Low iron-inducible periplasmic protein Cupin_3 PF05899.12 PSC68381.1 - 2.3e-06 27.2 0.0 6.3e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Kelch_2 PF07646.15 PSC68381.1 - 3e-06 27.0 0.0 2.2 8.4 0.0 5.0 4 0 0 4 4 4 2 Kelch motif AraC_binding PF02311.19 PSC68381.1 - 0.011 15.7 15.1 0.014 15.3 0.0 3.9 4 1 0 4 4 4 0 AraC-like ligand binding domain BACK PF07707.15 PSC68382.1 - 1.3e-05 25.2 0.0 2.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 BTB And C-terminal Kelch Med4 PF10018.9 PSC68382.1 - 0.0017 18.1 0.9 0.0034 17.1 0.9 1.4 1 0 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 PLAC9 PF15205.6 PSC68382.1 - 0.14 12.6 1.7 89 3.6 0.0 4.0 2 2 1 3 3 3 0 Placenta-specific protein 9 Ras PF00071.22 PSC68383.1 - 6e-67 224.3 0.9 7.2e-67 224.0 0.9 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PSC68383.1 - 5.9e-37 126.5 0.2 9.7e-37 125.8 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PSC68383.1 - 1.6e-17 63.5 0.1 1.8e-17 63.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PSC68383.1 - 6.5e-07 28.9 0.1 7.6e-07 28.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 PSC68383.1 - 9.6e-07 28.8 0.6 0.013 15.4 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 PSC68383.1 - 8.9e-06 25.8 0.1 1.5e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 PSC68383.1 - 1e-05 25.1 0.1 1.3e-05 24.7 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 PSC68383.1 - 6.9e-05 22.5 0.4 0.0002 21.0 0.2 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.29 PSC68383.1 - 0.00033 21.1 0.1 0.029 14.8 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PSC68383.1 - 0.0036 17.3 0.1 0.0091 16.0 0.1 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) FeoB_N PF02421.18 PSC68383.1 - 0.0042 16.6 0.1 0.018 14.5 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 PSC68383.1 - 0.0064 16.0 0.0 0.19 11.2 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 PSC68383.1 - 0.02 15.3 1.1 0.19 12.2 0.1 2.7 2 1 0 2 2 2 0 RNA helicase AAA_16 PF13191.6 PSC68383.1 - 0.025 14.9 0.0 0.041 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 PSC68383.1 - 0.031 14.0 0.1 2.1 8.1 0.0 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 PSC68383.1 - 0.034 14.4 0.0 0.083 13.2 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PSC68383.1 - 0.04 13.7 0.0 0.11 12.3 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dioxygenase_N PF04444.14 PSC68383.1 - 0.05 13.4 0.0 0.096 12.5 0.0 1.5 1 0 0 1 1 1 0 Catechol dioxygenase N terminus LANC_like PF05147.13 PSC68383.1 - 0.051 12.1 0.0 0.084 11.4 0.0 1.5 2 0 0 2 2 2 0 Lanthionine synthetase C-like protein Septin PF00735.18 PSC68383.1 - 0.069 12.4 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Septin TniB PF05621.11 PSC68383.1 - 0.1 12.0 0.0 0.24 10.8 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein ABC_tran PF00005.27 PSC68383.1 - 0.13 12.8 0.1 0.21 12.1 0.1 1.5 1 1 0 1 1 1 0 ABC transporter NACHT PF05729.12 PSC68383.1 - 0.18 11.7 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 PSC68384.1 - 6.1e-32 111.0 0.0 1.1e-31 110.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 PSC68384.1 - 3.9e-31 108.7 1.2 6.8e-31 107.9 1.2 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 PSC68384.1 - 0.00027 20.5 0.0 0.015 14.8 0.0 2.2 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PSC68384.1 - 0.0022 18.4 0.2 0.0081 16.6 0.2 2.1 1 1 0 1 1 1 1 AAA ATPase domain DUF87 PF01935.17 PSC68384.1 - 0.0022 18.1 0.0 0.0049 17.0 0.0 1.5 1 0 0 1 1 1 1 Helicase HerA, central domain AAA_22 PF13401.6 PSC68384.1 - 0.0026 18.0 0.0 0.0091 16.3 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 PSC68384.1 - 0.005 16.5 0.1 0.02 14.7 0.1 2.0 1 0 0 1 1 1 1 P-loop containing region of AAA domain K_channel_TID PF07941.11 PSC68384.1 - 0.0067 16.9 5.8 0.0067 16.9 5.8 4.4 4 0 0 4 4 2 2 Potassium channel Kv1.4 tandem inactivation domain DUF815 PF05673.13 PSC68384.1 - 0.012 14.8 0.0 0.022 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 PSC68384.1 - 0.032 13.6 0.2 0.11 11.8 0.0 1.9 2 0 0 2 2 2 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 PSC68384.1 - 0.032 14.1 0.0 0.068 13.1 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 PSC68384.1 - 0.11 12.6 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_5 PF07728.14 PSC68384.1 - 0.14 12.1 0.1 0.95 9.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Epiglycanin_C PF14654.6 PSC68384.1 - 0.26 11.3 3.4 0.18 11.9 0.4 2.2 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region Kelch_4 PF13418.6 PSC68385.1 - 3e-36 123.2 3.8 1.5e-06 28.1 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 PSC68385.1 - 8.5e-27 92.9 9.6 8.5e-05 22.7 0.2 6.7 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 PSC68385.1 - 2.3e-19 68.9 0.1 0.0012 18.7 0.0 6.5 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 PSC68385.1 - 1.3e-18 66.6 0.5 3.5e-05 23.9 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 PSC68385.1 - 7.4e-13 47.9 0.4 0.0024 17.4 0.0 4.3 4 0 0 4 4 4 3 Kelch motif Kelch_2 PF07646.15 PSC68385.1 - 2.4e-10 39.9 4.6 0.0029 17.5 0.0 5.1 5 0 0 5 5 5 3 Kelch motif RAG2 PF03089.14 PSC68385.1 - 0.017 14.1 0.0 3.3 6.6 0.0 2.5 3 0 0 3 3 3 0 Recombination activating protein 2 Transgly_assoc PF04226.13 PSC68385.1 - 0.028 14.7 1.0 0.069 13.4 1.0 1.6 1 0 0 1 1 1 0 Transglycosylase associated protein FAE1_CUT1_RppA PF08392.12 PSC68386.1 - 4.9e-132 439.6 0.0 6.4e-132 439.2 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein LsmAD PF06741.13 PSC68386.1 - 4.2e-21 75.3 0.6 7.6e-21 74.4 0.6 1.4 1 0 0 1 1 1 1 LsmAD domain SM-ATX PF14438.6 PSC68386.1 - 1.9e-15 56.8 0.0 3.5e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 Ataxin 2 SM domain Chal_sti_synt_C PF02797.15 PSC68386.1 - 4.2e-11 43.1 0.0 7.7e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.10 PSC68386.1 - 1.3e-10 41.3 0.0 3.1e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 PSC68386.1 - 0.0057 16.5 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III PAM2 PF07145.15 PSC68386.1 - 0.0089 15.7 4.2 0.01 15.5 2.5 2.1 1 1 0 1 1 1 1 Ataxin-2 C-terminal region Chal_sti_synt_N PF00195.19 PSC68386.1 - 0.024 14.1 0.1 0.051 13.0 0.1 1.5 1 0 0 1 1 1 0 Chalcone and stilbene synthases, N-terminal domain ATP-synt_J PF04911.12 PSC68387.1 - 0.0067 16.0 0.6 0.012 15.1 0.6 1.5 1 1 0 1 1 1 1 ATP synthase j chain Biopterin_H PF00351.21 PSC68388.1 - 4.9e-99 331.5 0.0 6.2e-99 331.2 0.0 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase Aldo_ket_red PF00248.21 PSC68389.1 - 1.6e-42 145.7 0.0 1.9e-42 145.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Elong-fact-P_C PF09285.11 PSC68390.1 - 2.5e-16 59.2 0.3 4.3e-16 58.4 0.3 1.4 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP PF01132.20 PSC68390.1 - 1.3e-15 57.1 0.0 2.8e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain EFP_N PF08207.12 PSC68390.1 - 1.5e-11 44.1 0.0 6.6e-11 42.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain ABC_membrane PF00664.23 PSC68391.1 - 9.1e-35 120.6 4.7 1.5e-34 119.9 4.7 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PSC68391.1 - 9.6e-28 97.4 0.0 1.5e-27 96.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PSC68391.1 - 1.1e-05 25.0 0.0 0.00012 21.6 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 PSC68391.1 - 0.0033 17.3 0.3 0.64 9.8 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 PSC68391.1 - 0.012 14.5 0.0 0.024 13.4 0.0 1.4 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_22 PF13401.6 PSC68391.1 - 0.022 15.0 0.2 0.25 11.6 0.2 2.2 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PSC68391.1 - 0.03 14.3 0.2 1.3 9.0 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RsgA_GTPase PF03193.16 PSC68391.1 - 0.064 13.2 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 PSC68391.1 - 0.086 12.6 0.1 0.18 11.6 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain 2OG-FeII_Oxy_3 PF13640.6 PSC68392.1 - 3.1e-09 37.6 0.0 1.4e-08 35.5 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 PSC68393.1 - 7.2e-10 39.6 0.0 3.8e-09 37.3 0.0 2.1 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Orai-1 PF07856.12 PSC68395.1 - 1.4e-34 119.3 1.0 1.4e-34 119.3 1.0 1.8 3 0 0 3 3 3 1 Mediator of CRAC channel activity DUF751 PF05421.11 PSC68395.1 - 7e-19 68.3 4.8 7e-19 68.3 4.8 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF751) C2 PF00168.30 PSC68395.1 - 5.5e-15 55.5 0.0 9.7e-15 54.7 0.0 1.4 1 0 0 1 1 1 1 C2 domain Jiraiya PF15038.6 PSC68395.1 - 0.026 14.0 0.5 0.026 14.0 0.5 3.2 3 1 0 3 3 3 0 Jiraiya DUF599 PF04654.12 PSC68395.1 - 0.47 9.8 8.2 0.17 11.2 4.8 2.0 1 1 1 2 2 2 0 Protein of unknown function, DUF599 TPH PF13868.6 PSC68396.1 - 1.6e-50 171.6 123.9 1.6e-50 171.6 123.9 2.2 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain RITA PF17066.5 PSC68396.1 - 0.0083 15.7 0.1 0.0083 15.7 0.1 2.7 2 1 0 2 2 2 1 RBPJ-interacting and tubulin associated protein Kinesin PF00225.23 PSC68398.1 - 5.2e-95 318.2 0.0 1.5e-94 316.6 0.0 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PSC68398.1 - 5.4e-13 49.1 0.0 1.7e-08 34.6 0.0 2.7 2 0 0 2 2 2 2 Microtubule binding Bestrophin PF01062.21 PSC68398.1 - 0.075 12.4 0.0 0.075 12.4 0.0 5.8 5 2 2 7 7 7 0 Bestrophin, RFP-TM, chloride channel Kinesin PF00225.23 PSC68399.1 - 5.2e-95 318.2 0.0 1.5e-94 316.6 0.0 1.8 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PSC68399.1 - 5.4e-13 49.1 0.0 1.7e-08 34.6 0.0 2.7 2 0 0 2 2 2 2 Microtubule binding Bestrophin PF01062.21 PSC68399.1 - 0.075 12.4 0.0 0.075 12.4 0.0 5.8 5 2 2 7 7 7 0 Bestrophin, RFP-TM, chloride channel DUF707 PF05212.12 PSC68400.1 - 0.0081 15.5 0.0 0.32 10.2 0.0 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF707) Mod_r PF07200.13 PSC68401.1 - 5.9e-25 88.1 1.4 5.9e-25 88.1 1.4 1.4 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein Exonuc_VII_S PF02609.16 PSC68401.1 - 0.0034 17.4 0.5 0.0034 17.4 0.5 1.9 2 0 0 2 2 2 1 Exonuclease VII small subunit UQ_con PF00179.26 PSC68401.1 - 0.0099 15.5 0.0 0.018 14.7 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF1707 PF08044.11 PSC68401.1 - 3 8.0 9.4 0.34 11.0 3.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) UQ_con PF00179.26 PSC68403.1 - 1.3e-25 89.7 0.0 1.5e-25 89.4 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PSC68403.1 - 0.00075 19.2 0.0 0.00099 18.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B UFC1 PF08694.11 PSC68403.1 - 0.18 11.4 0.0 0.25 11.0 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 TENA_THI-4 PF03070.16 PSC68404.1 - 8.6e-30 104.1 0.1 2.3e-29 102.7 0.0 1.6 2 0 0 2 2 2 1 TENA/THI-4/PQQC family SET PF00856.28 PSC68405.1 - 1.1e-12 48.7 0.0 5.4e-11 43.2 0.0 2.5 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 PSC68405.1 - 0.002 18.2 6.7 0.0025 17.9 4.1 2.6 2 0 0 2 2 2 1 MYND finger Sigma70_r2 PF04542.14 PSC68406.1 - 1e-19 70.1 1.9 7.4e-19 67.3 0.0 2.9 3 0 0 3 3 3 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 PSC68406.1 - 1.9e-08 33.7 2.0 2.4e-07 30.2 0.7 4.6 5 0 0 5 5 5 3 Sigma-70, region 4 Sigma70_r3 PF04539.16 PSC68406.1 - 0.0003 20.8 0.5 0.0043 17.1 0.1 2.5 2 0 0 2 2 2 1 Sigma-70 region 3 Sigma70_r1_2 PF00140.20 PSC68406.1 - 0.02 14.9 0.0 0.054 13.5 0.0 1.8 1 0 0 1 1 1 0 Sigma-70 factor, region 1.2 HSD3 PF15244.6 PSC68406.1 - 0.13 11.8 3.8 0.2 11.1 3.8 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 7, or HSD3 PBP_sp32 PF07222.12 PSC68406.1 - 0.13 11.7 5.4 0.26 10.7 5.4 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 PAXNEB PF05625.11 PSC68407.1 - 4.1e-36 124.9 0.0 1.4e-18 67.2 0.1 2.0 1 1 1 2 2 2 2 PAXNEB protein EspF PF04806.12 PSC68407.1 - 0.13 12.7 0.2 0.13 12.7 0.2 2.4 3 0 0 3 3 3 0 EspF protein repeat Herpes_capsid PF06112.11 PSC68407.1 - 1 9.4 6.4 0.078 13.1 1.4 1.7 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein RNase_H2-Ydr279 PF09468.10 PSC68408.1 - 6.5e-12 45.9 0.0 1.8e-11 44.5 0.0 1.7 1 1 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 PSC68408.1 - 5.9e-06 26.5 0.0 1.2e-05 25.4 0.0 1.5 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain TPP_enzyme_N PF02776.18 PSC68409.1 - 3.3e-52 176.6 0.0 9.8e-51 171.8 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 PSC68409.1 - 1.1e-43 148.2 0.1 2.1e-43 147.3 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 PSC68409.1 - 8.5e-43 145.8 0.1 7e-42 142.8 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Molybdopterin PF00384.22 PSC68409.1 - 0.022 13.7 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin oxidoreductase TPP_enzyme_N PF02776.18 PSC68410.1 - 3.3e-52 176.6 0.0 9.8e-51 171.8 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 PSC68410.1 - 1.1e-43 148.2 0.1 2.1e-43 147.3 0.1 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 PSC68410.1 - 8.5e-43 145.8 0.1 7e-42 142.8 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Molybdopterin PF00384.22 PSC68410.1 - 0.022 13.7 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin oxidoreductase DUF4864 PF16156.5 PSC68411.1 - 1.6e-08 35.1 0.0 5.1e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4864) DUF1664 PF07889.12 PSC68412.1 - 2.4e-29 101.9 0.9 1.4e-28 99.4 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) DUF3450 PF11932.8 PSC68412.1 - 0.017 14.5 0.8 0.097 12.0 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Apolipoprotein PF01442.18 PSC68412.1 - 0.026 14.4 4.4 0.19 11.6 1.9 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF1525 PF07511.11 PSC68412.1 - 0.04 14.1 0.1 0.44 10.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) STAT_alpha PF01017.20 PSC68412.1 - 0.11 12.4 0.1 1.4 8.8 0.0 2.1 2 0 0 2 2 2 0 STAT protein, all-alpha domain Rx_N PF18052.1 PSC68412.1 - 0.29 11.4 0.9 0.79 10.0 0.1 2.1 2 1 0 2 2 2 0 Rx N-terminal domain Nab1 PF04902.12 PSC68412.1 - 0.3 11.5 2.4 0.38 11.1 1.3 1.6 2 0 0 2 2 2 0 Conserved region in Nab1 SlyX PF04102.12 PSC68412.1 - 3.7 8.2 6.0 34 5.1 0.1 3.0 2 1 1 3 3 3 0 SlyX DUF1664 PF07889.12 PSC68413.1 - 3.2e-29 101.5 0.9 1.8e-28 99.1 0.2 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) DUF3450 PF11932.8 PSC68413.1 - 0.02 14.2 0.7 0.12 11.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Apolipoprotein PF01442.18 PSC68413.1 - 0.034 14.0 4.3 0.23 11.3 1.9 2.2 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF1525 PF07511.11 PSC68413.1 - 0.053 13.7 0.1 0.5 10.5 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) STAT_alpha PF01017.20 PSC68413.1 - 0.14 12.1 0.1 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 STAT protein, all-alpha domain Nab1 PF04902.12 PSC68413.1 - 0.46 10.9 2.7 0.45 10.9 1.3 1.6 2 0 0 2 2 2 0 Conserved region in Nab1 SlyX PF04102.12 PSC68413.1 - 4.6 7.9 5.9 40 4.9 0.1 3.0 2 1 1 3 3 3 0 SlyX UQ_con PF00179.26 PSC68416.1 - 6.4e-47 158.7 0.0 7.2e-47 158.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PSC68416.1 - 0.0012 18.6 0.0 0.0015 18.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B FAD_binding_6 PF00970.24 PSC68419.1 - 5.9e-31 106.7 0.0 9.4e-31 106.1 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 PSC68419.1 - 6e-29 100.9 0.0 8.6e-29 100.4 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 PSC68419.1 - 1.1e-05 25.6 0.0 0.00014 22.0 0.0 2.1 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_9 PF08021.11 PSC68419.1 - 0.14 12.4 0.0 0.23 11.7 0.0 1.4 1 0 0 1 1 1 0 Siderophore-interacting FAD-binding domain Glyco_hydro_18 PF00704.28 PSC68420.1 - 0.024 14.4 0.0 0.041 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 CAP_N PF01213.19 PSC68420.1 - 0.029 13.9 0.6 0.074 12.5 0.8 1.5 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal MTS PF05175.14 PSC68421.1 - 3.8e-08 33.1 0.0 4.8e-06 26.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_24 PF13578.6 PSC68421.1 - 2.2e-07 31.9 1.2 7.4e-06 26.9 0.1 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC68421.1 - 3.7e-06 27.6 0.0 9.2e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PSC68421.1 - 0.00046 19.7 0.7 0.00073 19.0 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 PSC68421.1 - 0.00055 20.5 0.5 0.00099 19.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC68421.1 - 0.00075 20.2 1.6 0.00076 20.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC68421.1 - 0.0029 17.5 0.2 0.0054 16.6 0.2 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC68421.1 - 0.0033 17.2 0.0 0.0054 16.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CheR PF01739.18 PSC68421.1 - 0.004 16.6 0.0 0.0056 16.2 0.0 1.2 1 0 0 1 1 1 1 CheR methyltransferase, SAM binding domain rRNA_methylase PF06962.12 PSC68421.1 - 0.01 15.8 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 Putative rRNA methylase Methyltransf_18 PF12847.7 PSC68421.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 PSC68421.1 - 0.027 13.7 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase UPF0020 PF01170.18 PSC68421.1 - 0.048 13.4 0.0 0.093 12.4 0.0 1.5 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Transglut_core PF01841.19 PSC68421.1 - 0.052 14.0 0.2 4.9 7.6 0.0 2.2 2 0 0 2 2 2 0 Transglutaminase-like superfamily PCMT PF01135.19 PSC68421.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 PSC68421.1 - 0.17 11.8 0.3 1.2 9.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain AviRa PF11599.8 PSC68421.1 - 0.2 11.1 0.1 0.2 11.1 0.1 2.1 2 0 0 2 2 2 0 RRNA methyltransferase AviRa Sugar_tr PF00083.24 PSC68422.1 - 3.8e-61 207.3 20.7 4.8e-61 207.0 20.7 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PSC68422.1 - 1.1e-19 70.7 20.3 1.1e-19 70.7 20.3 2.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Ephrin_rec_like PF07699.13 PSC68423.1 - 1.7e-39 133.3 136.6 9.4e-08 31.7 9.7 15.2 2 2 13 16 16 16 15 Putative ephrin-receptor like VSP PF03302.13 PSC68423.1 - 0.54 9.1 104.6 1.1 8.0 23.3 6.6 1 1 5 6 6 6 0 Giardia variant-specific surface protein TNFR_c6 PF00020.18 PSC68423.1 - 1.1 9.7 87.7 1.2 9.5 0.2 15.6 7 4 8 16 16 16 0 TNFR/NGFR cysteine-rich region Fasciclin PF02469.22 PSC68424.1 - 5.4e-09 36.3 0.1 7e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 Fasciclin domain RTX_C PF08339.10 PSC68424.1 - 0.11 12.5 0.2 0.24 11.4 0.2 1.5 1 1 1 2 2 2 0 RTX C-terminal domain YCII PF03795.14 PSC68425.1 - 3.4e-07 30.6 0.0 5.7e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 YCII-related domain DUF3873 PF12989.7 PSC68425.1 - 0.19 12.1 0.1 0.3 11.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) Methyltransf_11 PF08241.12 PSC68426.1 - 2.9e-11 43.9 0.0 6.9e-11 42.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC68426.1 - 2.5e-06 28.1 0.0 8.2e-06 26.4 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC68426.1 - 4.4e-06 26.6 0.0 6.4e-06 26.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC68426.1 - 7.7e-05 22.1 0.0 0.0001 21.7 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 PSC68426.1 - 0.00035 21.3 0.0 0.00071 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC68426.1 - 0.0004 20.3 0.0 0.00048 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 PSC68426.1 - 0.11 11.0 0.0 0.15 10.5 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase MetW PF07021.12 PSC68426.1 - 0.13 11.9 0.0 0.18 11.4 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW LSM PF01423.22 PSC68427.1 - 4.3e-20 71.2 0.3 5.6e-20 70.8 0.3 1.1 1 0 0 1 1 1 1 LSM domain Exonuc_VII_L PF02601.15 PSC68429.1 - 1.5 8.3 11.7 0.46 10.0 3.5 2.1 2 0 0 2 2 2 0 Exonuclease VII, large subunit rRNA_proc-arch PF13234.6 PSC68430.1 - 1.8e-64 218.3 0.0 6.8e-64 216.4 0.0 2.0 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 PSC68430.1 - 2.2e-44 151.0 0.3 5.7e-44 149.7 0.3 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 PSC68430.1 - 1.3e-17 64.2 0.0 3.6e-17 62.7 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC68430.1 - 3.2e-06 27.5 0.0 7.3e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain APG6_N PF17675.1 PSC68430.1 - 0.26 11.8 4.1 0.27 11.8 0.8 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region UFD1 PF03152.14 PSC68431.1 - 2.1e-30 105.5 0.0 2.9e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 UBX PF00789.20 PSC68431.1 - 2.7e-10 40.3 0.0 5.7e-10 39.3 0.0 1.5 1 0 0 1 1 1 1 UBX domain PGAP1 PF07819.13 PSC68432.1 - 0.00017 21.4 0.0 0.0015 18.3 0.0 2.1 1 1 0 1 1 1 1 PGAP1-like protein Lipase_2 PF01674.18 PSC68432.1 - 0.001 18.6 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 PSC68432.1 - 0.0017 18.1 0.0 0.015 14.9 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold DUF676 PF05057.14 PSC68432.1 - 0.01 15.4 0.0 0.015 14.8 0.0 1.2 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 PSC68432.1 - 0.015 14.5 0.0 0.027 13.7 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Palm_thioest PF02089.15 PSC68432.1 - 0.028 14.2 0.0 0.051 13.4 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase LCAT PF02450.15 PSC68432.1 - 0.062 12.5 0.0 0.087 12.0 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF4311 PF14188.6 PSC68432.1 - 0.097 12.4 0.1 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4311) DUF900 PF05990.12 PSC68432.1 - 0.25 10.8 0.0 0.4 10.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 PSC68432.1 - 1.3 9.6 18.8 9.1 6.8 18.5 2.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family PNP_UDP_1 PF01048.20 PSC68433.1 - 4.7e-38 130.8 0.7 7.2e-38 130.2 0.7 1.2 1 0 0 1 1 1 1 Phosphorylase superfamily FAD_binding_1 PF00667.20 PSC68435.1 - 5.4e-47 160.2 0.0 7.3e-47 159.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 PSC68435.1 - 1.5e-25 90.1 0.0 2.6e-25 89.3 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 PSC68435.1 - 3.1e-18 66.4 0.0 5.7e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 PSC68435.1 - 0.015 15.5 0.0 0.034 14.4 0.0 1.6 1 0 0 1 1 1 0 Flavodoxin domain TMEM18 PF14770.6 PSC68436.1 - 1.8e-38 131.1 3.2 2.5e-38 130.7 3.2 1.2 1 0 0 1 1 1 1 Transmembrane protein 18 NUDIX PF00293.28 PSC68436.1 - 5.8e-17 62.0 0.0 1e-16 61.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 PSC68436.1 - 0.016 15.2 0.1 0.052 13.5 0.0 1.8 2 0 0 2 2 2 0 NUDIX domain TadE PF07811.12 PSC68436.1 - 0.51 10.7 6.3 0.24 11.7 0.7 3.1 3 0 0 3 3 3 0 TadE-like protein HemY_N PF07219.13 PSC68436.1 - 1.1 9.5 4.2 0.31 11.3 0.6 1.9 1 1 1 2 2 2 0 HemY protein N-terminus TMEM18 PF14770.6 PSC68437.1 - 1.9e-38 131.1 3.2 2.6e-38 130.7 3.2 1.2 1 0 0 1 1 1 1 Transmembrane protein 18 NUDIX PF00293.28 PSC68437.1 - 2.3e-17 63.3 0.0 4.1e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 PSC68437.1 - 0.015 15.3 0.2 0.053 13.5 0.0 1.9 2 0 0 2 2 2 0 NUDIX domain HemY_N PF07219.13 PSC68437.1 - 0.2 11.8 0.1 0.2 11.8 0.1 1.9 2 1 0 2 2 2 0 HemY protein N-terminus TadE PF07811.12 PSC68437.1 - 0.53 10.6 6.3 0.25 11.7 0.7 3.1 3 0 0 3 3 3 0 TadE-like protein TAL_FSA PF00923.19 PSC68438.1 - 1.5e-88 296.9 0.0 1.7e-88 296.7 0.0 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase PAP2_C PF14360.6 PSC68439.1 - 1.3e-17 64.1 10.7 3e-17 62.9 10.7 1.7 1 0 0 1 1 1 1 PAP2 superfamily C-terminal Gal-3-0_sulfotr PF06990.11 PSC68439.1 - 0.00033 19.7 0.9 0.0007 18.6 0.9 1.4 1 0 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 PSC68439.1 - 0.00035 20.5 0.0 0.0026 17.7 0.0 2.3 1 1 0 1 1 1 1 Sulfotransferase family PAP2_3 PF14378.6 PSC68439.1 - 0.025 14.3 11.1 0.068 12.9 11.1 1.7 1 0 0 1 1 1 0 PAP2 superfamily DUF2569 PF10754.9 PSC68439.1 - 1.6 9.1 11.3 0.026 15.0 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2569) PAP2 PF01569.21 PSC68439.1 - 3 7.6 9.3 4.4 7.1 8.8 1.6 1 1 0 1 1 1 0 PAP2 superfamily Arm PF00514.23 PSC68440.1 - 1.4e-08 34.4 14.9 6e-05 22.9 0.3 6.0 6 1 1 7 7 7 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 PSC68440.1 - 0.075 13.4 30.6 0.044 14.2 5.0 5.1 2 1 4 6 6 6 0 HEAT repeats GATase_2 PF00310.21 PSC68440.1 - 0.19 10.4 0.1 0.27 9.9 0.1 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II zf_CCCH_4 PF18345.1 PSC68441.1 - 0.00017 21.5 2.3 0.00033 20.6 2.3 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 PSC68441.1 - 0.00023 20.9 2.4 0.00046 19.9 2.4 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-met PF12874.7 PSC68441.1 - 0.00078 19.8 0.5 0.56 10.7 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-CCCH PF00642.24 PSC68441.1 - 0.0061 16.4 2.0 0.014 15.3 2.0 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C2H2_4 PF13894.6 PSC68441.1 - 0.0066 17.2 10.2 0.018 15.8 0.3 2.5 2 0 0 2 2 2 1 C2H2-type zinc finger zf_ZIC PF18366.1 PSC68441.1 - 0.068 13.3 0.6 0.25 11.5 0.0 2.3 3 0 0 3 3 3 0 Zic proteins zinc finger domain zf-C2H2 PF00096.26 PSC68441.1 - 0.1 13.1 0.2 0.1 13.1 0.2 2.2 2 0 0 2 2 2 0 Zinc finger, C2H2 type DUF3824 PF12868.7 PSC68441.1 - 0.29 11.8 3.5 0.65 10.7 3.5 1.5 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Serglycin PF04360.12 PSC68441.1 - 0.48 10.4 2.5 1.3 9.0 2.5 1.7 1 0 0 1 1 1 0 Serglycin DUF1995 PF09353.10 PSC68442.1 - 4e-27 95.5 0.0 4.5e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) PNK3P PF08645.11 PSC68443.1 - 5.3e-43 146.5 0.0 1e-42 145.6 0.0 1.5 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase HHH_8 PF14716.6 PSC68443.1 - 5.8e-10 39.4 0.2 1.2e-09 38.4 0.2 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain HAD PF12710.7 PSC68443.1 - 0.077 13.4 0.0 0.19 12.1 0.0 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Herpes_capsid PF06112.11 PSC68444.1 - 0.00035 20.7 2.6 0.00035 20.7 2.6 1.9 2 0 0 2 2 2 1 Gammaherpesvirus capsid protein TFIIA PF03153.13 PSC68444.1 - 0.0021 18.2 11.1 0.0022 18.0 11.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 PSC68444.1 - 0.21 10.3 3.3 0.27 9.9 3.3 1.1 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 PSC68444.1 - 2.8 7.2 8.6 4.3 6.6 8.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Tubulin PF00091.25 PSC68445.1 - 1.6e-69 234.0 0.0 2.5e-69 233.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PSC68445.1 - 1.3e-41 141.7 0.0 2.4e-41 140.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 PSC68445.1 - 2.9e-05 24.3 0.0 6.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 PSC68445.1 - 0.04 13.1 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Tubulin like DnaJ PF00226.31 PSC68446.1 - 4.4e-15 55.5 0.2 8.6e-15 54.6 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 PSC68446.1 - 0.02 14.9 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin DnaJ PF00226.31 PSC68447.1 - 4.7e-15 55.5 0.2 9e-15 54.6 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain Thioredoxin PF00085.20 PSC68447.1 - 0.021 14.8 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin Fasciclin PF02469.22 PSC68448.1 - 1e-16 61.3 0.1 1.2e-16 61.1 0.1 1.1 1 0 0 1 1 1 1 Fasciclin domain Dzip-like_N PF13815.6 PSC68448.1 - 0.024 14.6 0.1 0.034 14.1 0.1 1.2 1 0 0 1 1 1 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Methyltransf_5 PF01795.19 PSC68448.1 - 0.11 12.0 0.1 0.18 11.3 0.1 1.3 1 1 0 1 1 1 0 MraW methylase family RTX_C PF08339.10 PSC68448.1 - 0.12 12.4 0.2 0.26 11.3 0.2 1.6 1 1 1 2 2 2 0 RTX C-terminal domain LCM PF04072.14 PSC68449.1 - 5.5e-10 39.5 0.0 1.8e-06 28.0 0.0 2.2 1 1 1 2 2 2 2 Leucine carboxyl methyltransferase Ssl1 PF04056.14 PSC68451.1 - 2.5e-67 226.4 0.0 3.4e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 Ssl1-like LCM PF04072.14 PSC68451.1 - 6.9e-33 114.2 0.0 4.1e-31 108.4 0.0 2.4 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase C1_4 PF07975.12 PSC68451.1 - 1.8e-14 53.7 5.7 1.8e-14 53.7 5.7 2.6 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 PSC68451.1 - 2.8e-08 34.4 0.0 6.1e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain IBR PF01485.21 PSC68451.1 - 0.0011 19.2 3.1 0.0011 19.2 3.1 2.4 2 0 0 2 2 2 1 IBR domain, a half RING-finger domain DZR PF12773.7 PSC68451.1 - 0.26 11.3 22.8 4.9 7.3 5.8 3.7 2 1 1 3 3 3 0 Double zinc ribbon Tubulin PF00091.25 PSC68452.1 - 1.6e-69 234.0 0.0 2.5e-69 233.4 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PSC68452.1 - 1.3e-41 141.7 0.0 2.4e-41 140.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 PSC68452.1 - 2.9e-05 24.3 0.0 6.3e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 PSC68452.1 - 0.04 13.1 0.0 0.061 12.5 0.0 1.3 1 0 0 1 1 1 0 Tubulin like Herpes_capsid PF06112.11 PSC68453.1 - 0.00051 20.1 2.6 0.00051 20.1 2.6 2.5 3 0 0 3 3 3 1 Gammaherpesvirus capsid protein TFIIA PF03153.13 PSC68453.1 - 0.0037 17.3 10.1 0.0046 17.0 10.1 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 PSC68453.1 - 0.36 9.6 2.8 0.46 9.2 2.8 1.1 1 0 0 1 1 1 0 Presenilin RLL PF10036.9 PSC68454.1 - 6.5e-57 193.3 0.0 8.6e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein RLL PF10036.9 PSC68455.1 - 6.5e-57 193.3 0.0 8.6e-57 192.9 0.0 1.1 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein SBP PF03110.14 PSC68456.1 - 7.3e-22 77.5 11.9 7.3e-22 77.5 11.9 2.1 2 0 0 2 2 2 1 SBP domain FAM176 PF14851.6 PSC68456.1 - 3.3 7.4 6.5 2.4 7.8 4.0 1.9 2 0 0 2 2 2 0 FAM176 family rve PF00665.26 PSC68457.1 - 1.4e-18 67.2 0.0 3.2e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Peptidase_C26 PF07722.13 PSC68457.1 - 1.9e-16 60.5 0.0 4.4e-16 59.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 PSC68457.1 - 3.8e-10 39.8 0.0 1e-09 38.5 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase class-I rve_3 PF13683.6 PSC68457.1 - 0.011 15.5 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain TMEM18 PF14770.6 PSC68459.1 - 1.6e-38 131.3 3.2 2.2e-38 130.9 3.2 1.2 1 0 0 1 1 1 1 Transmembrane protein 18 NUDIX PF00293.28 PSC68459.1 - 3.6e-17 62.6 0.0 6.1e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 PSC68459.1 - 0.011 15.7 0.2 0.038 14.0 0.1 1.9 2 0 0 2 2 2 0 NUDIX domain Bac_export_2 PF01312.19 PSC68459.1 - 0.13 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family TadE PF07811.12 PSC68459.1 - 0.41 11.0 6.3 0.22 11.8 0.7 3.2 3 0 0 3 3 3 0 TadE-like protein TMEM18 PF14770.6 PSC68460.1 - 1.6e-38 131.3 3.2 2.2e-38 130.8 3.2 1.2 1 0 0 1 1 1 1 Transmembrane protein 18 NUDIX PF00293.28 PSC68460.1 - 1.4e-17 63.9 0.0 2.5e-17 63.2 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 PSC68460.1 - 0.01 15.8 0.2 0.039 13.9 0.1 1.9 2 0 0 2 2 2 0 NUDIX domain Bac_export_2 PF01312.19 PSC68460.1 - 0.14 11.4 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family TadE PF07811.12 PSC68460.1 - 0.43 10.9 6.3 0.23 11.8 0.7 3.2 3 0 0 3 3 3 0 TadE-like protein Host_attach PF10116.9 PSC68461.1 - 0.082 13.5 2.2 1.3 9.6 0.7 2.4 2 1 0 2 2 2 0 Protein required for attachment to host cells SR-25 PF10500.9 PSC68461.1 - 0.52 9.9 6.1 0.76 9.3 6.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Amidase PF01425.21 PSC68462.1 - 2.3e-58 198.2 5.6 1.4e-57 195.7 5.6 1.9 1 1 0 1 1 1 1 Amidase Form_Nir_trans PF01226.17 PSC68462.1 - 3.5e-19 69.1 4.2 6.5e-19 68.2 4.2 1.4 1 0 0 1 1 1 1 Formate/nitrite transporter PLAC8 PF04749.17 PSC68463.1 - 4.3 8.4 6.3 53 4.9 0.3 3.2 2 1 0 2 2 2 0 PLAC8 family Abhydrolase_1 PF00561.20 PSC68464.1 - 2.3e-06 27.5 0.1 0.012 15.3 0.0 2.9 3 0 0 3 3 3 2 alpha/beta hydrolase fold PGAP1 PF07819.13 PSC68464.1 - 0.00013 21.8 0.0 0.0011 18.8 0.0 2.0 1 1 0 1 1 1 1 PGAP1-like protein Lipase_2 PF01674.18 PSC68464.1 - 0.00083 18.9 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_6 PF12697.7 PSC68464.1 - 0.0055 17.3 15.2 0.012 16.2 15.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 PSC68464.1 - 0.0083 15.7 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 PSC68464.1 - 0.0098 15.2 0.0 0.019 14.2 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 PSC68464.1 - 0.015 15.1 0.0 0.023 14.6 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase LCAT PF02450.15 PSC68464.1 - 0.049 12.8 0.0 0.067 12.3 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 PSC68464.1 - 0.22 11.0 0.0 0.32 10.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_1 PF00561.20 PSC68465.1 - 2.2e-06 27.5 0.1 0.012 15.3 0.0 2.9 3 0 0 3 3 3 2 alpha/beta hydrolase fold PGAP1 PF07819.13 PSC68465.1 - 0.00013 21.8 0.0 0.0011 18.8 0.0 2.0 1 1 0 1 1 1 1 PGAP1-like protein Lipase_2 PF01674.18 PSC68465.1 - 0.00082 18.9 0.0 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 2) Abhydrolase_6 PF12697.7 PSC68465.1 - 0.0054 17.3 15.2 0.012 16.3 15.2 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 PSC68465.1 - 0.0083 15.7 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 PSC68465.1 - 0.0097 15.2 0.0 0.019 14.2 0.0 1.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Palm_thioest PF02089.15 PSC68465.1 - 0.015 15.1 0.0 0.022 14.6 0.0 1.4 1 0 0 1 1 1 0 Palmitoyl protein thioesterase LCAT PF02450.15 PSC68465.1 - 0.049 12.8 0.0 0.067 12.4 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase DUF900 PF05990.12 PSC68465.1 - 0.22 11.0 0.0 0.32 10.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Pkinase PF00069.25 PSC68466.1 - 2.4e-57 194.3 0.0 3.6e-57 193.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC68466.1 - 6.4e-39 133.8 0.0 1e-38 133.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC68466.1 - 0.0034 16.8 0.0 0.0088 15.4 0.0 1.7 1 0 0 1 1 1 1 Kinase-like zf-C2H2_4 PF13894.6 PSC68466.1 - 1.3 10.1 5.8 13 6.9 2.1 3.1 2 0 0 2 2 2 0 C2H2-type zinc finger TFIIA PF03153.13 PSC68466.1 - 7.7 6.4 18.6 0.18 11.7 10.8 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MFS_1 PF07690.16 PSC68467.1 - 2.3e-22 79.4 44.9 2.8e-22 79.1 37.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 PSC68467.1 - 5.4e-20 71.2 3.0 2.8e-08 32.5 0.1 3.2 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 PSC68467.1 - 2e-08 33.6 14.9 9.1e-07 28.1 14.9 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter Sigma70_r1_2 PF00140.20 PSC68468.1 - 0.095 12.7 14.2 10 6.2 0.1 5.0 5 0 0 5 5 5 0 Sigma-70 factor, region 1.2 Ribosomal_S18 PF01084.20 PSC68468.1 - 0.24 11.7 7.3 21 5.4 0.1 4.7 5 0 0 5 5 5 0 Ribosomal protein S18 Ribosomal_S13_N PF08069.12 PSC68468.1 - 6 7.0 15.2 22 5.2 1.7 4.0 3 0 0 3 3 3 0 Ribosomal S13/S15 N-terminal domain SPC12 PF06645.13 PSC68469.1 - 2.6e-24 85.1 0.0 3.2e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) MerC PF03203.14 PSC68469.1 - 0.0005 20.5 0.0 0.0005 20.5 0.0 1.1 1 0 0 1 1 1 1 MerC mercury resistance protein DUF1929 PF09118.11 PSC68470.1 - 7.8e-51 170.3 0.1 3.4e-13 49.7 0.0 4.6 4 0 0 4 4 4 4 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.11 PSC68470.1 - 4.9e-33 114.3 0.0 1.2e-07 31.2 0.0 5.9 4 1 0 4 4 4 4 Glyoxal oxidase N-terminus Kelch_6 PF13964.6 PSC68470.1 - 8.8e-19 67.1 26.0 0.21 11.9 0.0 16.3 16 3 2 18 18 18 6 Kelch motif Kelch_1 PF01344.25 PSC68470.1 - 1.9e-10 40.2 6.8 8.7 6.0 0.1 11.4 12 0 0 12 12 12 2 Kelch motif Kelch_2 PF07646.15 PSC68470.1 - 3.9e-10 39.3 11.4 0.68 10.0 0.0 10.1 12 0 0 12 12 12 3 Kelch motif Kelch_4 PF13418.6 PSC68470.1 - 0.0054 16.7 18.8 11 6.1 0.1 10.6 11 1 1 12 12 12 1 Galactose oxidase, central domain Kelch_3 PF13415.6 PSC68470.1 - 0.064 13.6 7.4 3.1 8.2 0.0 6.0 6 0 0 6 6 6 0 Galactose oxidase, central domain DUF5122 PF17164.4 PSC68470.1 - 0.086 13.1 6.2 1.4e+02 2.9 0.0 6.7 7 0 0 7 7 7 0 Domain of unknown function (DUF5122) beta-propeller HIRAN PF08797.11 PSC68471.1 - 1.6e-05 24.7 0.0 2.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 HIRAN domain HIRAN PF08797.11 PSC68472.1 - 2.4e-07 30.6 0.0 3.9e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 HIRAN domain adh_short PF00106.25 PSC68474.1 - 7.1e-36 123.5 0.2 6.6e-29 100.8 0.5 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PSC68474.1 - 5.5e-22 78.5 0.3 5.9e-21 75.1 0.1 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC68474.1 - 1.2e-08 35.1 2.3 2.3e-08 34.2 2.3 1.5 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 PSC68474.1 - 0.00047 19.7 0.0 0.00088 18.8 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KDZ PF18758.1 PSC68475.1 - 2.7e-15 56.6 1.1 3.7e-15 56.2 1.1 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase PMSR PF01625.21 PSC68476.1 - 1.3e-05 25.4 1.4 0.00043 20.5 0.2 2.4 2 1 0 2 2 2 2 Peptide methionine sulfoxide reductase CcmD PF04995.14 PSC68477.1 - 0.076 13.1 1.2 0.11 12.5 1.2 1.3 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) NAPRTase PF04095.16 PSC68478.1 - 3.3e-34 118.6 0.0 4.7e-34 118.1 0.0 1.2 1 0 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF5598 PF18127.1 PSC68478.1 - 1.5e-13 51.0 0.0 2.5e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5598) kleA_kleC PF17383.2 PSC68478.1 - 0.33 11.3 0.9 3.9 7.9 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized KorC regulated protein A MFS_1 PF07690.16 PSC68479.1 - 3.6e-45 154.4 31.5 3.6e-45 154.4 31.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 PSC68479.1 - 0.017 13.5 6.6 3.4 5.8 0.0 3.1 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family DUF2407 PF10302.9 PSC68479.1 - 0.2 12.2 0.0 0.42 11.2 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain DUF4864 PF16156.5 PSC68480.1 - 1.7e-08 35.1 0.0 5.2e-08 33.5 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4864) Peptidase_S8 PF00082.22 PSC68481.1 - 2.7e-32 112.2 8.2 6.4e-32 111.0 8.2 1.6 1 1 0 1 1 1 1 Subtilase family CybS PF05328.12 PSC68485.1 - 1.9e-09 37.3 0.1 3.1e-09 36.6 0.1 1.3 1 1 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Glyco_transf_92 PF01697.27 PSC68486.1 - 1.5e-15 57.6 0.0 2.7e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PSC68486.1 - 1.3e-11 44.8 0.0 1.3e-11 44.8 0.0 3.6 3 1 1 4 4 4 1 Glycosyl transferase family 2 CCSAP PF15748.5 PSC68486.1 - 0.035 14.3 7.8 0.063 13.4 7.8 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated TFIIA PF03153.13 PSC68486.1 - 1.6 8.6 24.1 2.1 8.2 24.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1772 PF08592.11 PSC68487.1 - 2e-09 37.8 5.6 2e-09 37.8 5.6 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF1772) DUF1772 PF08592.11 PSC68488.1 - 2.3e-09 37.7 5.7 2.3e-09 37.7 5.7 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF1772) SSB PF00436.25 PSC68489.1 - 1.8e-18 66.5 0.0 2.8e-18 65.9 0.0 1.3 1 0 0 1 1 1 1 Single-strand binding protein family tRNA_anti-codon PF01336.25 PSC68489.1 - 0.086 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Prismane PF03063.20 PSC68490.1 - 8.3e-142 473.5 0.0 9.7e-142 473.2 0.0 1.0 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family LRR_8 PF13855.6 PSC68490.1 - 2.3e-06 27.3 0.8 0.0019 17.9 0.1 2.9 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PSC68490.1 - 0.0012 19.2 2.5 0.034 14.6 0.0 3.3 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) Sulfotransfer_3 PF13469.6 PSC68491.1 - 3.4e-07 30.9 1.4 3.9e-05 24.1 0.1 3.0 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PSC68491.1 - 7.3e-05 22.4 0.0 0.00019 21.0 0.0 1.6 1 1 0 1 1 1 1 Sulfotransferase domain NAD_kinase PF01513.21 PSC68491.1 - 0.099 11.8 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 ATP-NAD kinase Nop14 PF04147.12 PSC68491.1 - 0.65 8.1 6.4 0.88 7.7 6.4 1.1 1 0 0 1 1 1 0 Nop14-like family TEX19 PF15553.6 PSC68491.1 - 1.7 8.6 6.9 4 7.4 6.9 1.7 1 0 0 1 1 1 0 Testis-expressed protein 19 HMGL-like PF00682.19 PSC68492.1 - 1.8e-87 293.3 0.0 2.9e-87 292.6 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 PSC68492.1 - 1.2e-35 122.3 0.4 2.2e-35 121.5 0.4 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain HMGL-like PF00682.19 PSC68493.1 - 1.8e-87 293.3 0.0 2.9e-87 292.6 0.0 1.4 1 0 0 1 1 1 1 HMGL-like LeuA_dimer PF08502.10 PSC68493.1 - 1.2e-35 122.3 0.4 2.2e-35 121.5 0.4 1.5 1 0 0 1 1 1 1 LeuA allosteric (dimerisation) domain V-SNARE_C PF12352.8 PSC68494.1 - 1.2e-10 41.6 0.0 3.5e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus Snf7 PF03357.21 PSC68494.1 - 5.1e-07 29.5 11.0 5.1e-07 29.5 11.0 3.7 3 1 1 4 4 4 1 Snf7 zf-PARP PF00645.18 PSC68494.1 - 5.7e-06 27.1 0.0 5.7e-06 27.1 0.0 3.2 4 0 0 4 4 4 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region HeLo PF14479.6 PSC68494.1 - 0.1 12.4 0.0 0.1 12.4 0.0 3.3 4 0 0 4 4 4 0 Prion-inhibition and propagation V-SNARE_C PF12352.8 PSC68495.1 - 6.5e-11 42.4 0.0 2.1e-10 40.7 0.0 1.8 1 0 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus zf-PARP PF00645.18 PSC68495.1 - 3.5e-06 27.8 0.0 3.5e-06 27.8 0.0 2.6 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region BSP_II PF05432.11 PSC68495.1 - 0.3 10.7 44.4 0.56 9.8 44.4 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) SAPS PF04499.15 PSC68495.1 - 0.51 9.1 7.9 0.66 8.7 7.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 PSC68495.1 - 1.4 8.2 34.0 2.3 7.6 34.0 1.3 1 0 0 1 1 1 0 SDA1 CDC27 PF09507.10 PSC68495.1 - 7.8 5.8 31.8 15 4.9 31.8 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ras PF00071.22 PSC68496.1 - 6.4e-22 77.9 0.0 1.4e-19 70.2 0.0 2.4 2 1 0 2 2 2 2 Ras family Roc PF08477.13 PSC68496.1 - 2.2e-17 63.4 0.0 5e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SET PF00856.28 PSC68496.1 - 7.1e-10 39.5 0.0 5e-07 30.3 0.0 3.1 2 1 0 2 2 2 1 SET domain Dynamin_N PF00350.23 PSC68496.1 - 0.007 16.4 0.1 0.05 13.7 0.0 2.1 2 0 0 2 2 2 1 Dynamin family Arf PF00025.21 PSC68496.1 - 0.0073 15.8 0.0 0.64 9.4 0.0 2.2 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PSC68496.1 - 0.0085 15.7 0.0 0.55 9.7 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PSC68496.1 - 0.026 14.6 0.0 0.049 13.7 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase MCM PF00493.23 PSC68496.1 - 0.099 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain Septin PF00735.18 PSC68496.1 - 0.23 10.7 0.0 0.41 9.9 0.0 1.4 1 0 0 1 1 1 0 Septin Spt20 PF12090.8 PSC68496.1 - 6.6 6.3 11.7 9 5.8 5.3 2.0 2 0 0 2 2 2 0 Spt20 family Ras PF00071.22 PSC68497.1 - 2.6e-25 88.9 0.0 5.2e-24 84.7 0.0 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 PSC68497.1 - 2.1e-20 73.2 0.0 4e-20 72.2 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SET PF00856.28 PSC68497.1 - 4.1e-10 40.3 0.1 6.1e-07 30.0 0.0 3.1 2 1 0 3 3 3 1 SET domain Arf PF00025.21 PSC68497.1 - 0.0026 17.2 0.0 0.25 10.8 0.0 2.1 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PSC68497.1 - 0.0055 16.3 0.0 0.43 10.1 0.0 2.3 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 PSC68497.1 - 0.0059 16.7 0.1 0.046 13.8 0.0 2.1 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 PSC68497.1 - 0.016 15.2 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 PSC68497.1 - 0.061 13.6 0.0 0.28 11.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain MCM PF00493.23 PSC68497.1 - 0.094 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain Septin PF00735.18 PSC68497.1 - 0.2 10.9 0.0 0.37 10.0 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_28 PF13521.6 PSC68497.1 - 2 8.6 0.0 2 8.6 0.0 3.1 3 0 0 3 3 3 0 AAA domain Spt20 PF12090.8 PSC68497.1 - 5.7 6.5 11.7 8.3 5.9 5.3 2.0 2 0 0 2 2 2 0 Spt20 family CBS PF00571.28 PSC68498.1 - 1.9e-14 53.8 4.1 8.8e-10 38.9 1.4 3.5 3 1 0 3 3 3 2 CBS domain DnaJ PF00226.31 PSC68498.1 - 3e-14 52.9 1.4 4.8e-14 52.2 1.4 1.3 1 0 0 1 1 1 1 DnaJ domain Shisa PF13908.6 PSC68498.1 - 0.017 15.4 0.0 0.029 14.6 0.0 1.5 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator OAD_gamma PF04277.13 PSC68498.1 - 2.8 8.6 6.5 0.34 11.5 0.3 2.6 1 1 1 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Retinal PF15449.6 PSC68499.1 - 2.7 5.7 22.8 3.2 5.4 22.8 1.0 1 0 0 1 1 1 0 Retinal protein Pkinase PF00069.25 PSC68500.1 - 9.1e-48 162.9 0.0 2.7e-47 161.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC68500.1 - 6e-47 160.1 0.0 3.1e-46 157.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 PSC68500.1 - 2.6e-14 53.1 11.1 0.0018 18.6 0.6 4.9 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC68500.1 - 4.9e-08 32.6 11.5 0.0062 16.3 2.3 4.7 3 2 1 4 4 4 3 Leucine rich repeat LRR_1 PF00560.33 PSC68500.1 - 0.00013 22.0 3.9 14 6.7 0.1 6.8 7 0 0 7 7 7 1 Leucine Rich Repeat Kdo PF06293.14 PSC68500.1 - 0.02 14.2 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PSC68500.1 - 0.087 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 PSC68500.1 - 0.28 10.7 0.0 0.51 9.9 0.0 1.4 1 0 0 1 1 1 0 RIO1 family DUF1350 PF07082.11 PSC68501.1 - 3.2e-33 115.1 0.0 1.4e-22 80.2 0.0 2.8 2 1 0 2 2 2 2 Protein of unknown function (DUF1350) MIP PF00230.20 PSC68501.1 - 1.4e-06 28.2 10.9 6e-06 26.1 0.2 3.5 2 1 1 3 3 3 2 Major intrinsic protein Rhomboid PF01694.22 PSC68502.1 - 1e-23 84.0 12.6 1e-23 84.0 12.6 2.3 3 0 0 3 3 3 1 Rhomboid family DER1 PF04511.15 PSC68502.1 - 0.0014 18.6 0.7 0.31 11.0 0.0 2.1 2 0 0 2 2 2 2 Der1-like family ATPase_gene1 PF09527.10 PSC68502.1 - 0.56 10.4 5.8 0.15 12.2 1.1 2.5 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter PCMT PF01135.19 PSC68503.1 - 8.1e-64 215.2 0.0 9.8e-64 215.0 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 PSC68503.1 - 7e-06 25.9 0.0 1.2e-05 25.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain GCD14 PF08704.10 PSC68503.1 - 1e-05 25.4 0.0 0.00069 19.4 0.0 2.1 1 1 1 2 2 2 1 tRNA methyltransferase complex GCD14 subunit PrmA PF06325.13 PSC68503.1 - 2.3e-05 23.9 0.0 2.6e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.17 PSC68503.1 - 8.9e-05 21.8 0.0 0.00013 21.2 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_32 PF13679.6 PSC68503.1 - 0.00013 22.0 0.0 0.00023 21.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC68503.1 - 0.00019 22.1 0.0 0.0005 20.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC68503.1 - 0.00071 19.4 0.0 0.0012 18.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC68503.1 - 0.0012 19.5 0.1 0.0039 17.8 0.1 1.9 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PSC68503.1 - 0.002 17.7 0.0 0.0038 16.8 0.0 1.4 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.18 PSC68503.1 - 0.0066 15.8 0.0 0.0094 15.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family RrnaAD PF00398.20 PSC68503.1 - 0.024 13.7 0.0 0.034 13.2 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Fibrillarin PF01269.17 PSC68503.1 - 0.037 13.2 0.0 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Fibrillarin Met_10 PF02475.16 PSC68503.1 - 0.04 13.7 0.0 0.08 12.7 0.0 1.4 1 0 0 1 1 1 0 Met-10+ like-protein MetW PF07021.12 PSC68503.1 - 0.11 12.1 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_18 PF12847.7 PSC68503.1 - 0.12 12.3 0.0 0.17 11.8 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 PSC68503.1 - 0.14 11.5 0.0 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase AviRa PF11599.8 PSC68503.1 - 0.19 11.1 0.0 0.27 10.7 0.0 1.2 1 0 0 1 1 1 0 RRNA methyltransferase AviRa DUF2207 PF09972.9 PSC68504.1 - 4e-05 22.6 3.3 0.044 12.6 0.3 2.6 3 0 0 3 3 3 2 Predicted membrane protein (DUF2207) DUF1640 PF07798.11 PSC68505.1 - 1.1e-54 185.2 12.9 1.4e-54 184.8 12.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1640) RasGAP_C PF03836.15 PSC68505.1 - 0.36 11.0 6.7 0.29 11.3 5.0 1.7 1 1 0 1 1 1 0 RasGAP C-terminus COBRA1 PF06209.13 PSC68506.1 - 8e-48 163.5 11.0 3.2e-28 98.9 2.8 2.8 2 1 0 2 2 2 2 Cofactor of BRCA1 (COBRA1) GRP PF07172.11 PSC68506.1 - 0.004 17.8 3.3 0.0092 16.6 3.3 1.5 1 0 0 1 1 1 1 Glycine rich protein family DPBB_1 PF03330.18 PSC68507.1 - 9.6e-05 22.6 0.2 0.00024 21.3 0.2 1.6 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 PSC68507.1 - 0.00023 21.0 0.8 0.00038 20.3 0.1 1.8 2 0 0 2 2 1 1 Barwin family RR_TM4-6 PF06459.12 PSC68507.1 - 0.001 19.0 8.4 0.0012 18.7 8.4 1.1 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Coilin_N PF15862.5 PSC68507.1 - 0.0011 18.7 9.1 0.0015 18.3 9.1 1.2 1 0 0 1 1 1 1 Coilin N-terminus SprA-related PF12118.8 PSC68507.1 - 0.0022 17.2 10.2 0.0026 16.9 10.2 1.1 1 0 0 1 1 1 1 SprA-related family DDHD PF02862.17 PSC68507.1 - 0.0037 17.5 1.7 0.004 17.3 1.7 1.1 1 0 0 1 1 1 1 DDHD domain SpoIIP PF07454.11 PSC68507.1 - 0.0041 16.6 7.9 0.0049 16.4 7.9 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) PIP5K PF01504.18 PSC68507.1 - 0.017 14.4 1.0 0.018 14.3 1.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase DUF5308 PF17233.2 PSC68507.1 - 0.03 14.6 0.9 0.036 14.3 0.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5308) SAPS PF04499.15 PSC68507.1 - 0.043 12.6 4.9 0.05 12.4 4.9 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein SDA1 PF05285.12 PSC68507.1 - 0.051 13.0 17.7 0.065 12.7 17.7 1.1 1 0 0 1 1 1 0 SDA1 ASC PF00858.24 PSC68507.1 - 0.062 12.3 7.1 0.082 11.9 7.1 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel PTPRCAP PF15713.5 PSC68507.1 - 0.064 13.5 19.7 0.098 12.9 19.7 1.2 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DUF913 PF06025.12 PSC68507.1 - 0.071 12.1 4.9 0.083 11.9 4.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) NPR3 PF03666.13 PSC68507.1 - 0.11 11.3 10.5 0.13 11.0 10.5 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SID-1_RNA_chan PF13965.6 PSC68507.1 - 0.12 10.8 0.0 0.12 10.8 0.0 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Eapp_C PF10238.9 PSC68507.1 - 0.14 12.2 9.1 0.24 11.5 9.1 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein CPSF100_C PF13299.6 PSC68507.1 - 0.16 12.2 9.1 0.22 11.7 9.1 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Neur_chan_memb PF02932.16 PSC68507.1 - 0.16 12.0 1.9 0.18 11.9 1.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Roughex PF06020.11 PSC68507.1 - 0.16 11.0 9.4 0.22 10.6 9.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Dsh_C PF12316.8 PSC68507.1 - 0.25 11.7 3.6 0.36 11.2 3.6 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Nop14 PF04147.12 PSC68507.1 - 0.27 9.4 16.1 0.34 9.1 16.1 1.0 1 0 0 1 1 1 0 Nop14-like family RRN3 PF05327.11 PSC68507.1 - 0.36 9.3 7.4 0.39 9.2 7.4 1.0 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RNA_pol_Rpc4 PF05132.14 PSC68507.1 - 0.36 11.2 12.3 0.52 10.7 12.3 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 Zip PF02535.22 PSC68507.1 - 0.49 9.6 5.5 0.65 9.1 5.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter MCM_bind PF09739.9 PSC68507.1 - 0.49 8.8 7.8 0.58 8.5 7.8 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor SLC12 PF03522.15 PSC68507.1 - 0.51 9.3 7.7 0.63 9.0 7.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF2151 PF10221.9 PSC68507.1 - 0.6 8.6 7.1 0.72 8.4 7.1 1.0 1 0 0 1 1 1 0 Cell cycle and development regulator Hid1 PF12722.7 PSC68507.1 - 0.68 8.0 6.8 0.82 7.7 6.8 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 PSC68507.1 - 0.77 8.5 13.0 1 8.1 13.0 1.1 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 PSC68507.1 - 0.82 10.7 9.7 1.5 9.9 9.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) PPL5 PF18168.1 PSC68507.1 - 0.88 8.8 10.8 1.3 8.2 10.8 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Vfa1 PF08432.10 PSC68507.1 - 1.2 9.5 18.1 1.7 8.9 18.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Pox_Ag35 PF03286.14 PSC68507.1 - 1.5 8.6 16.7 2.2 8.0 16.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.14 PSC68507.1 - 1.6 7.0 15.7 2 6.6 15.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Paramyxo_ncap PF00973.19 PSC68507.1 - 2.9 6.7 7.4 3.7 6.4 7.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein TFIIF_alpha PF05793.12 PSC68507.1 - 3.3 6.2 24.3 4.5 5.7 24.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Rrn6 PF10214.9 PSC68507.1 - 3.5 6.0 10.6 4.4 5.7 10.6 1.0 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4820 PF16091.5 PSC68507.1 - 3.7 6.8 12.4 5.3 6.3 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) RP-C_C PF11800.8 PSC68507.1 - 4.5 7.3 8.8 6.2 6.9 8.8 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Ureide_permease PF07168.11 PSC68507.1 - 4.6 5.9 5.5 6.2 5.5 5.5 1.2 1 0 0 1 1 1 0 Ureide permease PPP4R2 PF09184.11 PSC68507.1 - 5.3 6.6 17.7 7.5 6.0 17.7 1.1 1 0 0 1 1 1 0 PPP4R2 NARP1 PF12569.8 PSC68507.1 - 5.3 5.8 21.4 7 5.4 21.4 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Sec62 PF03839.16 PSC68507.1 - 5.8 6.4 11.2 7.9 5.9 11.2 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 Cellulose_synt PF03552.14 PSC68507.1 - 6.8 5.0 4.9 8.9 4.7 4.9 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF1980 PF09323.10 PSC68507.1 - 7 6.5 6.2 11 5.9 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) PBP1_TM PF14812.6 PSC68507.1 - 8.1 6.9 14.9 15 6.0 14.9 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal MDM10 PF12519.8 PSC68507.1 - 9.1 5.0 8.4 12 4.6 8.4 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Serinc PF03348.15 PSC68507.1 - 9.7 5.0 7.3 14 4.5 7.3 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Fe_bilin_red PF05996.12 PSC68508.1 - 0.018 14.8 0.0 1.1 8.9 0.0 2.1 2 0 0 2 2 2 0 Ferredoxin-dependent bilin reductase CCT PF06203.14 PSC68510.1 - 1.6e-16 60.0 10.7 2.9e-16 59.3 10.7 1.4 1 0 0 1 1 1 1 CCT motif zf-B_box PF00643.24 PSC68510.1 - 0.0074 16.4 0.5 0.014 15.5 0.5 1.4 1 0 0 1 1 1 1 B-box zinc finger RINGv PF12906.7 PSC68511.1 - 7e-07 29.3 6.8 1.3e-06 28.4 6.8 1.5 1 0 0 1 1 1 1 RING-variant domain FUSC PF04632.12 PSC68511.1 - 0.00037 19.2 9.1 0.0005 18.8 9.1 1.1 1 0 0 1 1 1 1 Fusaric acid resistance protein family DUF1192 PF06698.11 PSC68511.1 - 0.0068 16.4 3.9 0.71 10.0 0.3 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1192) zf-RING_2 PF13639.6 PSC68511.1 - 0.02 15.2 6.3 0.07 13.5 3.0 2.2 2 0 0 2 2 2 0 Ring finger domain DivIC PF04977.15 PSC68511.1 - 0.032 14.0 2.8 0.032 14.0 2.8 2.7 2 1 1 3 3 3 0 Septum formation initiator DUF812 PF05667.11 PSC68511.1 - 0.042 12.7 4.6 0.049 12.5 4.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Atg14 PF10186.9 PSC68511.1 - 0.09 11.8 6.5 0.12 11.5 6.5 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Rootletin PF15035.6 PSC68511.1 - 0.11 12.6 12.7 0.2 11.6 12.7 1.4 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF948 PF06103.11 PSC68511.1 - 0.11 12.7 3.3 1.8 8.9 0.3 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) bZIP_1 PF00170.21 PSC68511.1 - 0.18 11.9 6.0 0.21 11.7 4.4 1.9 1 1 1 2 2 2 0 bZIP transcription factor Exonuc_VII_L PF02601.15 PSC68511.1 - 0.19 11.3 6.9 0.25 10.9 6.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit TPD52 PF04201.15 PSC68511.1 - 0.2 11.3 2.8 0.34 10.5 2.8 1.4 1 0 0 1 1 1 0 Tumour protein D52 family Ax_dynein_light PF10211.9 PSC68511.1 - 0.21 11.5 8.9 0.17 11.8 7.1 1.7 1 1 1 2 2 2 0 Axonemal dynein light chain ZapB PF06005.12 PSC68511.1 - 0.23 11.9 10.3 0.13 12.7 6.7 2.2 2 1 1 3 3 3 0 Cell division protein ZapB CortBP2 PF09727.9 PSC68511.1 - 0.27 11.1 13.7 0.51 10.2 13.8 1.4 1 1 0 1 1 1 0 Cortactin-binding protein-2 KASH_CCD PF14662.6 PSC68511.1 - 0.32 10.8 9.7 0.26 11.1 4.3 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH LPP PF04728.13 PSC68511.1 - 0.32 11.4 6.9 1.8 9.0 0.1 2.7 2 0 0 2 2 2 0 Lipoprotein leucine-zipper NRBF2 PF08961.10 PSC68511.1 - 0.32 10.6 8.0 0.49 10.0 8.0 1.2 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator TPR_MLP1_2 PF07926.12 PSC68511.1 - 0.34 11.0 15.5 0.52 10.4 15.5 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein V_ATPase_I PF01496.19 PSC68511.1 - 0.36 8.7 3.7 0.46 8.3 3.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family YabA PF06156.13 PSC68511.1 - 0.38 11.4 5.2 0.42 11.3 2.4 2.3 1 1 1 2 2 2 0 Initiation control protein YabA DUF1664 PF07889.12 PSC68511.1 - 0.42 10.6 3.9 3.3 7.7 0.6 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF1664) ATG16 PF08614.11 PSC68511.1 - 0.43 10.8 17.0 1.1 9.5 17.0 1.5 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Cytochrom_B562 PF07361.11 PSC68511.1 - 0.6 10.8 10.8 0.79 10.4 2.0 2.3 1 1 1 2 2 2 0 Cytochrome b562 ADIP PF11559.8 PSC68511.1 - 2.8 8.0 14.5 0.99 9.5 11.1 1.8 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding CCCAP PF15964.5 PSC68511.1 - 3.7 5.7 16.2 6.5 4.9 15.6 1.5 1 1 1 2 2 2 0 Centrosomal colon cancer autoantigen protein family CorA PF01544.18 PSC68511.1 - 5.2 6.3 5.1 7.1 5.8 5.1 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SlyX PF04102.12 PSC68511.1 - 5.3 7.7 9.2 1.1 9.9 2.9 2.7 2 1 0 2 2 2 0 SlyX PRKG1_interact PF15898.5 PSC68511.1 - 5.8 7.9 14.0 56 4.7 14.0 2.2 1 1 0 1 1 1 0 cGMP-dependent protein kinase interacting domain EMP24_GP25L PF01105.24 PSC68511.1 - 5.9 6.8 5.3 31 4.4 5.2 2.0 1 1 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF724 PF05266.14 PSC68511.1 - 7 6.4 8.1 5.2 6.8 6.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF724) CENP-H PF05837.12 PSC68511.1 - 7.3 7.1 11.9 0.55 10.7 4.2 2.3 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Methyltransf_25 PF13649.6 PSC68512.1 - 4.5e-05 24.1 0.1 0.0003 21.4 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC68512.1 - 0.0056 17.3 0.2 0.096 13.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 PSC68512.1 - 0.015 15.1 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 PSC68512.1 - 0.082 12.7 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Presenilin PF01080.17 PSC68512.1 - 0.087 11.6 0.1 0.14 10.9 0.1 1.3 1 0 0 1 1 1 0 Presenilin RAM PF15320.6 PSC68512.1 - 6.7 7.4 10.2 1.2 9.7 5.4 2.1 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein TPR_1 PF00515.28 PSC68513.1 - 1.8e-23 81.3 24.5 0.0015 18.2 0.0 9.0 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_2 PF07719.17 PSC68513.1 - 1.1e-20 72.0 35.5 0.00027 20.8 1.0 9.7 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 PSC68513.1 - 7.1e-16 57.0 16.2 0.012 15.7 0.1 9.1 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 PSC68513.1 - 1.4e-12 48.0 32.2 9.5e-07 29.4 5.1 11.0 10 2 3 14 14 10 5 Tetratricopeptide repeat TPR_11 PF13414.6 PSC68513.1 - 1e-11 44.3 5.9 0.00057 19.5 0.0 5.5 4 1 1 5 5 5 3 TPR repeat TPR_9 PF13371.6 PSC68513.1 - 7.1e-10 38.9 52.2 0.00011 22.2 0.9 8.2 3 2 6 9 9 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 PSC68513.1 - 2.9e-08 33.5 7.0 1.5 9.4 0.0 6.7 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 PSC68513.1 - 2.3e-06 27.8 54.1 0.0023 18.2 4.3 8.5 5 2 6 11 11 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 PSC68513.1 - 2.8e-05 24.5 15.2 0.00037 20.9 0.6 8.3 8 2 1 10 10 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PSC68513.1 - 0.00019 21.6 9.8 0.019 15.1 0.1 4.4 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 PSC68513.1 - 0.0014 19.3 0.2 0.0014 19.3 0.2 13.4 8 2 7 15 15 13 4 Tetratricopeptide repeat TipAS PF07739.13 PSC68513.1 - 0.082 13.5 0.0 1.1 9.8 0.0 2.8 2 0 0 2 2 2 0 TipAS antibiotic-recognition domain TPR_7 PF13176.6 PSC68513.1 - 0.4 10.8 33.1 1 9.6 0.1 8.6 11 0 0 11 11 8 0 Tetratricopeptide repeat SR-25 PF10500.9 PSC68513.1 - 8.4 5.9 8.0 18 4.8 8.0 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BNR PF02012.20 PSC68514.1 - 0.038 14.0 0.5 0.73 10.1 0.1 3.0 2 0 0 2 2 2 0 BNR/Asp-box repeat KIX_2 PF16987.5 PSC68515.1 - 9.3e-06 25.5 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 KIX domain KIX_2 PF16987.5 PSC68516.1 - 9.3e-06 25.5 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 KIX domain Sulfotransfer_3 PF13469.6 PSC68517.1 - 4.7e-09 37.0 10.3 6.7e-09 36.5 0.2 4.0 2 1 1 3 3 3 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PSC68517.1 - 0.00012 21.7 0.1 0.00012 21.7 0.1 1.9 2 1 0 2 2 2 1 Sulfotransferase domain DUF1943 PF09172.11 PSC68517.1 - 0.01 15.1 4.1 0.015 14.5 4.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1943) DDHD PF02862.17 PSC68517.1 - 0.018 15.2 2.0 0.024 14.8 2.0 1.3 1 0 0 1 1 1 0 DDHD domain TFIIA PF03153.13 PSC68517.1 - 0.22 11.5 28.7 0.32 11.0 28.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Serinc PF03348.15 PSC68517.1 - 0.6 9.0 2.0 0.99 8.3 2.0 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) RR_TM4-6 PF06459.12 PSC68517.1 - 0.82 9.4 10.8 1.2 8.9 10.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SRP-alpha_N PF04086.13 PSC68517.1 - 0.84 9.5 13.1 1.3 8.8 13.1 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ndc1_Nup PF09531.10 PSC68517.1 - 4.4 5.9 6.3 5.8 5.5 6.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SAPS PF04499.15 PSC68517.1 - 4.7 5.9 10.4 6.8 5.4 10.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pex14_N PF04695.13 PSC68517.1 - 5.4 7.7 18.7 11 6.7 18.7 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM60A PF15396.6 PSC68517.1 - 5.5 6.9 7.1 9.2 6.2 7.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A PAT1 PF09770.9 PSC68517.1 - 7.2 4.7 20.7 10 4.3 20.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lin-8 PF03353.15 PSC68517.1 - 9.4 5.7 17.0 14 5.1 17.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Histone PF00125.24 PSC68518.1 - 2.4e-32 112.1 0.0 3.2e-32 111.6 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 PSC68518.1 - 0.027 14.8 0.0 0.044 14.2 0.0 1.3 1 0 0 1 1 1 0 CENP-S protein TFIID-31kDa PF02291.15 PSC68518.1 - 0.041 14.0 0.0 0.06 13.4 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T_C PF15511.6 PSC68518.1 - 0.06 13.5 0.1 0.13 12.4 0.0 1.6 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T histone fold Exostosin PF03016.15 PSC68519.1 - 5e-95 318.2 0.0 8.1e-47 159.9 0.0 2.3 2 0 0 2 2 2 2 Exostosin family TPR_21 PF09976.9 PSC68519.1 - 0.013 15.2 0.0 5.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat-like domain Imm6 PF14434.6 PSC68519.1 - 0.015 15.2 0.1 6.2 6.8 0.0 2.2 2 0 0 2 2 2 0 Immunity protein Imm6 DUF3856 PF12968.7 PSC68519.1 - 0.019 15.0 0.0 10 6.2 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) EGF_Tenascin PF18720.1 PSC68519.1 - 0.25 11.4 46.4 0.18 11.9 2.5 5.3 6 0 0 6 6 6 0 Tenascin EGF domain EGF_2 PF07974.13 PSC68519.1 - 1.6 9.1 120.7 0.019 15.3 19.4 8.9 9 0 0 9 9 9 0 EGF-like domain Sugar_tr PF00083.24 PSC68521.1 - 6.9e-27 94.4 21.8 5e-26 91.6 21.7 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PSC68521.1 - 4.6e-20 71.8 26.3 4.6e-20 71.8 26.3 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily RRM_1 PF00076.22 PSC68521.1 - 2e-14 53.2 0.0 3.5e-14 52.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PSC68521.1 - 5.8e-05 22.7 0.0 0.0001 21.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PSC68521.1 - 0.16 12.0 0.1 0.37 10.8 0.1 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Sugar_tr PF00083.24 PSC68522.1 - 3.9e-27 95.2 24.9 2.6e-26 92.5 24.9 1.9 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PSC68522.1 - 8.7e-20 70.9 28.2 8.7e-20 70.9 28.2 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily RRM_1 PF00076.22 PSC68522.1 - 2.1e-14 53.1 0.0 3.8e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PSC68522.1 - 6.1e-05 22.6 0.0 0.00011 21.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) WAPL PF07814.13 PSC68524.1 - 2.8e-22 79.0 0.0 4.7e-22 78.3 0.0 1.3 1 0 0 1 1 1 1 Wings apart-like protein regulation of heterochromatin Cupin_8 PF13621.6 PSC68525.1 - 8.8e-44 150.1 0.0 1.4e-43 149.4 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain ABC_tran PF00005.27 PSC68525.1 - 2e-36 125.5 0.0 8.8e-18 65.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter RLI PF04068.15 PSC68525.1 - 4.5e-12 45.6 6.3 9.1e-12 44.6 6.3 1.6 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI SMC_N PF02463.19 PSC68525.1 - 1.1e-10 41.3 2.6 0.007 15.8 0.0 4.1 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 PSC68525.1 - 4.7e-10 39.8 3.2 0.044 13.6 1.0 4.5 4 1 1 5 5 4 3 AAA domain, putative AbiEii toxin, Type IV TA system Fer4 PF00037.27 PSC68525.1 - 2.5e-08 33.4 3.5 2.5e-08 33.4 3.5 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain AAA PF00004.29 PSC68525.1 - 3.1e-07 30.9 0.0 0.0059 17.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Sulfotransfer_2 PF03567.14 PSC68525.1 - 7.7e-07 29.3 0.0 1.5e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family Fer4_6 PF12837.7 PSC68525.1 - 2.1e-05 24.4 2.8 2.1e-05 24.4 2.8 2.5 2 0 0 2 2 2 1 4Fe-4S binding domain AAA_15 PF13175.6 PSC68525.1 - 3.6e-05 23.6 0.0 0.09 12.5 0.0 2.6 3 0 0 3 3 3 2 AAA ATPase domain AAA_29 PF13555.6 PSC68525.1 - 5.6e-05 22.8 0.1 0.22 11.3 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 PSC68525.1 - 6.4e-05 23.2 0.4 0.031 14.5 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PSC68525.1 - 7.4e-05 23.2 2.2 1.3 9.4 0.0 3.7 3 1 0 3 3 3 2 AAA ATPase domain AAA_23 PF13476.6 PSC68525.1 - 0.00019 22.0 0.1 0.13 12.7 0.2 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 PSC68525.1 - 0.00021 21.2 0.1 0.13 12.1 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Fer4_2 PF12797.7 PSC68525.1 - 0.00022 21.1 0.8 0.00022 21.1 0.8 2.4 2 0 0 2 2 1 1 4Fe-4S binding domain AAA_33 PF13671.6 PSC68525.1 - 0.00053 20.2 0.2 1.6 8.9 0.0 3.2 2 1 0 2 2 2 2 AAA domain Cupin_4 PF08007.12 PSC68525.1 - 0.00068 19.2 0.1 0.12 11.8 0.0 2.4 2 0 0 2 2 2 1 Cupin superfamily protein SRP54 PF00448.22 PSC68525.1 - 0.00097 18.8 1.1 0.14 11.8 0.0 2.4 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_10 PF13237.6 PSC68525.1 - 0.002 18.2 1.2 0.002 18.2 1.2 2.7 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_21 PF14697.6 PSC68525.1 - 0.0028 17.7 12.0 0.0061 16.7 12.0 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 PSC68525.1 - 0.005 17.4 1.2 0.005 17.4 1.2 2.6 1 1 2 3 3 3 1 4Fe-4S dicluster domain NACHT PF05729.12 PSC68525.1 - 0.0058 16.6 0.3 0.39 10.6 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_5 PF07728.14 PSC68525.1 - 0.0071 16.4 0.4 0.9 9.5 0.0 2.9 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 PSC68525.1 - 0.0078 16.6 0.0 4.8 7.6 0.0 2.6 2 0 0 2 2 2 0 RNA helicase Thymidylate_kin PF02223.17 PSC68525.1 - 0.01 15.5 0.0 2.4 7.8 0.0 2.9 3 0 0 3 3 3 0 Thymidylate kinase Rad17 PF03215.15 PSC68525.1 - 0.011 15.7 0.0 0.53 10.2 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain TsaE PF02367.17 PSC68525.1 - 0.014 15.4 0.1 0.28 11.2 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Fer4_9 PF13187.6 PSC68525.1 - 0.016 15.4 12.2 0.038 14.2 12.2 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain AAA_7 PF12775.7 PSC68525.1 - 0.026 14.0 0.0 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 PSC68525.1 - 0.036 13.8 3.6 0.35 10.5 0.0 2.6 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.6 PSC68525.1 - 0.046 14.0 0.0 7.3 6.9 0.0 2.8 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.12 PSC68525.1 - 0.05 12.9 0.0 4.8 6.4 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 PSC68525.1 - 0.058 13.9 0.0 14 6.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Fer4_16 PF13484.6 PSC68525.1 - 0.065 14.2 0.2 0.065 14.2 0.2 2.8 2 0 0 2 2 2 0 4Fe-4S double cluster binding domain NTPase_1 PF03266.15 PSC68525.1 - 0.097 12.6 2.3 12 5.8 0.0 3.2 3 0 0 3 3 3 0 NTPase AAA_30 PF13604.6 PSC68525.1 - 0.11 12.2 7.2 3.1 7.5 0.0 3.4 4 0 0 4 4 3 0 AAA domain AAA_19 PF13245.6 PSC68525.1 - 0.2 12.0 0.1 7.2 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 PSC68525.1 - 0.24 11.4 0.1 11 6.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_13 PF13166.6 PSC68525.1 - 0.38 9.3 1.1 2.6 6.6 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 PSC68525.1 - 0.79 10.0 6.3 3.8 7.7 0.0 2.8 3 0 0 3 3 2 0 AAA domain Fer4_4 PF12800.7 PSC68525.1 - 2 9.1 14.8 0.3 11.7 2.7 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_8 PF13183.6 PSC68525.1 - 3.5 8.2 9.3 1.2 9.6 1.7 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 PSC68525.1 - 4.3 8.1 6.3 2.1 9.2 1.1 3.1 2 0 0 2 2 2 0 4Fe-4S single cluster domain PKcGMP_CC PF16808.5 PSC68526.1 - 6.3 6.8 10.4 8.7 6.3 0.1 4.4 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SMP_LBD PF17047.5 PSC68527.1 - 1.2e-10 41.2 0.0 1.7e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain C2 PF00168.30 PSC68527.1 - 0.1 12.9 0.0 0.19 12.0 0.0 1.4 1 0 0 1 1 1 0 C2 domain SART-1 PF03343.13 PSC68528.1 - 1.8e-84 284.5 61.1 7.3e-67 226.3 57.6 2.0 1 1 1 2 2 2 2 SART-1 family Dak1 PF02733.17 PSC68530.1 - 2.1e-94 315.9 0.9 2.1e-94 315.9 0.9 1.6 2 0 0 2 2 2 1 Dak1 domain Dak2 PF02734.17 PSC68530.1 - 1.7e-35 122.5 21.3 1.7e-35 122.5 21.3 2.3 2 0 0 2 2 2 1 DAK2 domain Umbravirus_LDM PF04817.12 PSC68530.1 - 0.097 12.0 0.9 0.18 11.1 0.9 1.4 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family Tim17 PF02466.19 PSC68531.1 - 1.3e-07 32.0 4.3 1.3e-07 32.0 4.3 2.0 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family Frankia_peptide PF14407.6 PSC68531.1 - 0.096 12.7 0.8 0.21 11.6 0.2 1.9 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. CRAL_TRIO PF00650.20 PSC68532.1 - 4.8e-14 52.4 0.0 4.6e-13 49.2 0.0 2.1 2 0 0 2 2 2 1 CRAL/TRIO domain SHE3 PF17078.5 PSC68532.1 - 0.013 15.2 6.0 0.041 13.6 5.8 1.9 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 CRAL_TRIO_2 PF13716.6 PSC68532.1 - 0.023 14.8 0.0 0.04 14.1 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain bZIP_1 PF00170.21 PSC68532.1 - 1.8 8.7 11.4 12 6.1 0.4 3.6 1 1 2 3 3 3 0 bZIP transcription factor Vta1 PF04652.16 PSC68533.1 - 1.4e-32 112.6 0.1 1.9e-32 112.2 0.1 1.2 1 0 0 1 1 1 1 Vta1 like Vta1_C PF18097.1 PSC68533.1 - 2e-10 40.2 0.5 2e-10 40.2 0.5 1.7 2 0 0 2 2 2 1 Vta1 C-terminal domain DUF3110 PF11360.8 PSC68534.1 - 9.8e-07 28.9 0.0 1.6e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3110) G_path_suppress PF15991.5 PSC68534.1 - 0.1 12.7 0.2 0.16 12.1 0.2 1.2 1 0 0 1 1 1 0 G-protein pathway suppressor RVT_2 PF07727.14 PSC68535.1 - 2.1e-66 224.1 0.0 2.6e-66 223.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PSC68535.1 - 1.6e-23 83.2 0.0 2.3e-22 79.4 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 PSC68535.1 - 5e-10 39.1 0.0 9.3e-10 38.2 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 PSC68535.1 - 7.4e-06 25.7 0.0 7e-05 22.5 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain AAA_23 PF13476.6 PSC68536.1 - 5.7e-31 108.6 3.8 5.7e-31 108.6 3.8 6.8 2 2 2 5 5 1 1 AAA domain SMC_N PF02463.19 PSC68536.1 - 3.1e-14 52.9 0.0 2.8e-06 27.0 0.0 2.3 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 PSC68536.1 - 1.1e-09 38.6 0.0 0.0015 18.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PSC68536.1 - 6.6e-09 35.9 11.1 3.1e-05 23.9 1.1 3.3 2 1 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 PSC68536.1 - 9.3e-06 25.8 0.0 5.4e-05 23.4 0.0 2.5 1 0 0 1 1 1 1 Putative exonuclease SbcCD, C subunit Golgin_A5 PF09787.9 PSC68536.1 - 0.004 16.7 14.0 0.004 16.7 14.0 7.9 3 3 4 8 8 8 1 Golgin subfamily A member 5 AAA_29 PF13555.6 PSC68536.1 - 0.0078 15.9 0.0 0.018 14.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF3220 PF11516.8 PSC68536.1 - 0.053 13.7 1.0 3.7 7.8 0.1 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3120) AAA_22 PF13401.6 PSC68536.1 - 0.28 11.4 0.0 0.28 11.4 0.0 4.4 5 2 0 5 5 5 0 AAA domain AAA_13 PF13166.6 PSC68536.1 - 0.36 9.4 0.0 0.36 9.4 0.0 7.8 4 2 3 7 7 6 0 AAA domain ABC_tran PF00005.27 PSC68536.1 - 2 8.9 28.2 0.68 10.4 6.5 6.3 2 2 0 2 2 1 0 ABC transporter DUF3531 PF12049.8 PSC68537.1 - 1.1e-48 164.8 0.1 1.7e-48 164.2 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3531) T2SSM PF04612.12 PSC68537.1 - 0.56 10.3 11.9 0.1 12.7 6.3 2.3 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M SBP PF03110.14 PSC68538.1 - 9.9e-18 64.2 7.2 9.9e-18 64.2 7.2 2.1 2 0 0 2 2 1 1 SBP domain Adaptin_binding PF10199.9 PSC68538.1 - 0.00026 21.6 0.0 0.0016 19.0 0.0 2.2 1 1 1 2 2 2 1 Alpha and gamma adaptin binding protein p34 PAT1 PF09770.9 PSC68538.1 - 0.0044 15.4 18.8 0.0051 15.2 18.8 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Neur_chan_memb PF02932.16 PSC68538.1 - 0.25 11.4 2.8 0.37 10.8 2.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 PSC68538.1 - 0.3 11.1 43.3 0.45 10.4 43.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 PSC68538.1 - 0.49 10.8 7.3 0.83 10.0 7.3 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF1980 PF09323.10 PSC68538.1 - 0.5 10.2 4.2 0.84 9.5 4.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) RR_TM4-6 PF06459.12 PSC68538.1 - 1.2 8.9 7.8 1.9 8.3 7.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FNIP_N PF14636.6 PSC68538.1 - 4.5 8.2 12.5 0.94 10.4 8.6 1.8 2 0 0 2 2 2 0 Folliculin-interacting protein N-terminus GREB1 PF15782.5 PSC68538.1 - 4.6 4.2 10.4 6.8 3.7 10.4 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pex26 PF07163.12 PSC68538.1 - 4.8 6.4 14.1 13 5.0 14.1 1.7 1 1 0 1 1 1 0 Pex26 protein DUF2464 PF10240.9 PSC68538.1 - 4.9 6.6 7.9 9.8 5.7 7.9 1.4 1 0 0 1 1 1 0 Multivesicular body subunit 12 Sugar_tr PF00083.24 PSC68539.1 - 2e-24 86.3 20.5 6.7e-24 84.6 20.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter HAUS4 PF14735.6 PSC68540.1 - 4e-28 98.7 0.0 7.8e-28 97.8 0.0 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 4 zf-RING_2 PF13639.6 PSC68540.1 - 2.2e-13 50.3 3.2 4e-13 49.5 3.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PSC68540.1 - 5.4e-09 35.7 2.7 9.3e-09 35.0 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PSC68540.1 - 1.4e-07 31.1 0.7 2.7e-07 30.2 0.7 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 PSC68540.1 - 3.2e-07 30.5 5.7 9.2e-07 29.1 5.7 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PSC68540.1 - 1.8e-06 27.7 1.3 3.2e-06 26.9 1.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC68540.1 - 0.00011 22.1 1.2 0.00019 21.3 1.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PSC68540.1 - 0.00013 21.9 0.9 0.00026 20.9 0.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PSC68540.1 - 0.00045 20.0 1.7 0.00085 19.1 1.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PSC68540.1 - 0.0025 17.8 1.0 0.005 16.9 1.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 PSC68540.1 - 0.023 14.9 2.7 0.027 14.7 1.3 1.9 2 1 0 2 2 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 PSC68540.1 - 0.14 11.8 2.1 0.39 10.4 2.1 1.7 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 PSC68540.1 - 0.14 12.0 4.0 0.56 10.1 3.8 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 PHD PF00628.29 PSC68540.1 - 0.31 10.9 2.1 0.73 9.8 2.1 1.7 1 0 0 1 1 1 0 PHD-finger EPL1 PF10513.9 PSC68541.1 - 2.5e-11 44.2 3.0 6.6e-10 39.6 0.1 2.5 2 0 0 2 2 2 2 Enhancer of polycomb-like Spt20 PF12090.8 PSC68541.1 - 0.37 10.4 6.8 0.66 9.5 6.8 1.4 1 0 0 1 1 1 0 Spt20 family NST1 PF13945.6 PSC68541.1 - 7.4 6.6 6.7 20 5.2 6.7 1.7 1 0 0 1 1 1 0 Salt tolerance down-regulator CRAL_TRIO PF00650.20 PSC68542.1 - 6.4e-30 104.0 0.0 9e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain SBP PF03110.14 PSC68542.1 - 4.8e-18 65.2 3.5 4.8e-18 65.2 3.5 1.8 2 0 0 2 2 2 1 SBP domain Hydrolase_4 PF12146.8 PSC68542.1 - 1.8e-08 34.0 0.1 3.5e-05 23.2 0.0 2.7 1 1 1 2 2 2 2 Serine aminopeptidase, S33 CRAL_TRIO_2 PF13716.6 PSC68542.1 - 3.1e-05 24.2 0.0 5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Abhydrolase_1 PF00561.20 PSC68542.1 - 0.032 13.9 0.1 0.38 10.3 0.1 2.4 1 1 1 2 2 2 0 alpha/beta hydrolase fold Shikimate_DH PF01488.20 PSC68543.1 - 2.2e-42 144.4 0.0 4e-42 143.5 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase GlutR_N PF05201.15 PSC68543.1 - 2.8e-40 137.4 0.0 5.3e-40 136.5 0.0 1.5 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, N-terminal domain GlutR_dimer PF00745.20 PSC68543.1 - 1.9e-26 92.3 0.0 4.7e-26 91.1 0.0 1.7 1 0 0 1 1 1 1 Glutamyl-tRNAGlu reductase, dimerisation domain F420_oxidored PF03807.17 PSC68543.1 - 2.9e-06 27.8 0.4 4.7e-05 23.9 0.0 3.0 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 PSC68543.1 - 0.0037 17.5 0.1 0.02 15.2 0.0 2.3 3 0 0 3 3 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_2 PF03446.15 PSC68543.1 - 0.0037 17.4 0.0 0.0084 16.3 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase OCD_Mu_crystall PF02423.15 PSC68543.1 - 0.0047 15.9 0.0 0.0084 15.1 0.0 1.3 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family NAD_binding_7 PF13241.6 PSC68543.1 - 0.015 15.8 0.0 0.043 14.3 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding NAD_binding_10 PF13460.6 PSC68543.1 - 0.022 14.7 0.1 0.083 12.8 0.0 2.0 2 1 0 2 2 2 0 NAD(P)H-binding Glu_dehyd_C PF16912.5 PSC68543.1 - 0.039 13.4 0.1 0.061 12.8 0.1 1.3 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus ApbA PF02558.16 PSC68543.1 - 0.071 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.19 PSC68543.1 - 0.09 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PI_PP_I PF18363.1 PSC68545.1 - 0.037 14.2 4.0 21 5.4 0.0 5.8 4 2 2 6 6 6 0 Phosphoinositide phosphatase insertion domain Cir_N PF10197.9 PSC68546.1 - 6.4e-05 23.1 6.1 6.4e-05 23.1 6.1 5.3 6 0 0 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR SR-25 PF10500.9 PSC68546.1 - 0.0066 16.1 21.9 0.0066 16.1 21.9 2.2 2 1 0 2 2 2 1 Nuclear RNA-splicing-associated protein Glyco_trans_1_2 PF13524.6 PSC68546.1 - 0.01 16.2 0.4 0.01 16.2 0.4 2.5 2 0 0 2 2 2 0 Glycosyl transferases group 1 CagY_M PF07337.11 PSC68546.1 - 0.048 13.3 1.8 1.3 8.7 0.1 2.6 2 0 0 2 2 2 0 DC-EC Repeat Nucleo_P87 PF07267.11 PSC68546.1 - 1.9 7.2 7.7 2.6 6.8 7.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 F-box-like PF12937.7 PSC68547.1 - 8.8e-07 28.7 0.5 1.9e-06 27.7 0.5 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PSC68547.1 - 0.00069 19.4 0.4 0.0012 18.7 0.4 1.3 1 0 0 1 1 1 1 F-box domain RskA PF10099.9 PSC68548.1 - 0.00028 21.2 3.9 0.00035 20.9 3.9 1.1 1 0 0 1 1 1 1 Anti-sigma-K factor rskA CAP_N PF01213.19 PSC68548.1 - 0.0017 17.9 5.1 0.002 17.7 5.1 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 PSC68548.1 - 4.1 7.5 13.4 8.1 6.5 13.4 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Peptidase_M48 PF01435.18 PSC68549.1 - 1.4e-33 116.4 1.1 4.5e-33 114.7 0.2 2.2 2 1 0 2 2 2 1 Peptidase family M48 PPR_2 PF13041.6 PSC68549.1 - 5.4e-28 97.0 0.0 8.3e-09 35.5 0.0 5.2 4 2 2 6 6 6 4 PPR repeat family PPR PF01535.20 PSC68549.1 - 2.8e-27 93.0 1.2 7.5e-05 22.7 0.0 8.0 9 0 0 9 9 9 5 PPR repeat PPR_3 PF13812.6 PSC68549.1 - 4.6e-21 74.6 0.0 1.1e-06 28.6 0.0 4.4 3 1 0 4 4 4 3 Pentatricopeptide repeat domain PPR_1 PF12854.7 PSC68549.1 - 5.4e-21 74.0 0.0 2.9e-06 26.9 0.0 4.8 5 0 0 5 5 5 3 PPR repeat PPR_long PF17177.4 PSC68549.1 - 9.3e-12 44.8 0.1 0.00011 21.7 0.2 2.9 1 1 1 3 3 3 2 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 PSC68549.1 - 0.00011 22.7 21.8 0.051 14.4 0.7 6.8 6 2 1 7 7 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 PSC68549.1 - 0.00012 21.9 3.6 1.3 9.2 0.0 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 PSC68549.1 - 0.00075 19.7 8.9 0.0011 19.2 1.7 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_15 PF13429.6 PSC68549.1 - 0.018 14.2 1.3 0.03 13.5 1.3 1.2 1 0 0 1 1 1 0 Tetratricopeptide repeat Clathrin PF00637.20 PSC68549.1 - 0.051 13.5 0.0 2.8 7.8 0.0 2.5 2 1 0 2 2 2 0 Region in Clathrin and VPS TPR_1 PF00515.28 PSC68549.1 - 0.088 12.7 0.7 79 3.3 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 PSC68549.1 - 0.47 11.0 10.2 0.75 10.3 0.2 3.7 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 PSC68549.1 - 1.6 9.1 8.5 4.3 7.7 0.3 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 PSC68549.1 - 4.2 7.8 7.5 1.2 9.6 0.9 3.1 3 1 2 5 5 4 0 Bacterial transcriptional activator domain TPR_6 PF13174.6 PSC68549.1 - 8.9 7.2 8.7 89 4.0 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat zf-rbx1 PF12678.7 PSC68550.1 - 4.5e-07 30.1 3.0 4.5e-07 30.1 3.0 1.8 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 PSC68550.1 - 4.2e-06 27.0 8.4 7.3e-06 26.2 4.6 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 PSC68550.1 - 4.5e-05 23.2 2.3 4.5e-05 23.2 2.3 1.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PSC68550.1 - 0.00019 21.4 1.0 0.00053 20.0 1.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 PSC68550.1 - 0.00061 19.8 2.6 0.00061 19.8 2.6 2.0 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 PSC68550.1 - 0.00065 19.6 3.4 0.0019 18.1 3.4 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 PSC68550.1 - 0.0015 18.3 2.1 0.027 14.2 0.5 2.5 2 0 0 2 2 2 1 RING-like zinc finger FANCL_C PF11793.8 PSC68550.1 - 0.0028 17.8 1.6 0.0028 17.8 1.6 1.7 2 0 0 2 2 1 1 FANCL C-terminal domain zf-C3HC4_3 PF13920.6 PSC68550.1 - 0.046 13.6 7.3 0.025 14.4 4.6 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PSC68550.1 - 0.29 10.8 3.4 0.82 9.3 3.4 1.8 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_2 PF13923.6 PSC68550.1 - 0.29 11.0 11.7 0.031 14.1 6.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PSC68550.1 - 1.2 9.3 5.4 2.7 8.2 5.4 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PSC68550.1 - 2.2 8.2 10.4 0.15 12.0 4.5 2.1 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 WD40 PF00400.32 PSC68551.1 - 2.3e-26 91.5 21.4 8.1e-06 26.5 0.0 6.8 6 1 1 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC68551.1 - 0.00089 19.5 0.4 1.2 9.4 0.0 3.1 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 PSC68551.1 - 0.03 13.1 0.0 2.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Nup133 N terminal like Nup160 PF11715.8 PSC68551.1 - 0.066 11.8 1.4 14 4.2 0.0 3.8 3 1 1 4 4 4 0 Nucleoporin Nup120/160 HEAT PF02985.22 PSC68552.1 - 0.034 14.4 0.2 0.18 12.2 0.2 2.3 1 0 0 1 1 1 0 HEAT repeat Hamartin PF04388.12 PSC68552.1 - 0.37 9.4 15.0 0.95 8.0 15.0 1.6 1 0 0 1 1 1 0 Hamartin protein Ad_cyc_g-alpha PF08509.11 PSC68553.1 - 0.53 10.1 2.1 19 5.1 0.1 2.8 2 0 0 2 2 2 0 Adenylate cyclase G-alpha binding domain Ad_cyc_g-alpha PF08509.11 PSC68554.1 - 0.53 10.0 2.3 17 5.2 0.1 2.8 2 0 0 2 2 2 0 Adenylate cyclase G-alpha binding domain Ad_cyc_g-alpha PF08509.11 PSC68555.1 - 0.53 10.0 2.3 17 5.2 0.1 2.8 2 0 0 2 2 2 0 Adenylate cyclase G-alpha binding domain Mcm10 PF09332.11 PSC68556.1 - 1e-20 74.5 14.0 4.3e-19 69.1 5.7 2.4 2 0 0 2 2 2 2 Mcm10 replication factor zf-primase PF09329.11 PSC68556.1 - 1.2e-15 57.0 0.1 1.2e-15 57.0 0.1 1.9 2 0 0 2 2 2 1 Primase zinc finger MMR_HSR1 PF01926.23 PSC68556.1 - 0.47 10.5 9.5 1.9 8.6 2.4 3.2 2 1 0 2 2 2 0 50S ribosome-binding GTPase Snf7 PF03357.21 PSC68557.1 - 2e-08 34.0 11.0 2.5e-08 33.7 11.0 1.1 1 0 0 1 1 1 1 Snf7 PduV-EutP PF10662.9 PSC68557.1 - 0.097 12.4 1.2 0.15 11.8 0.1 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Ist1 PF03398.14 PSC68557.1 - 0.15 12.0 7.6 3.6 7.5 7.6 2.0 1 1 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway ABC_tran_CTD PF16326.5 PSC68557.1 - 1.9 8.8 7.5 0.65 10.3 0.5 3.2 2 1 2 4 4 4 0 ABC transporter C-terminal domain Lon_C PF05362.13 PSC68558.1 - 5.4e-68 228.6 0.0 9.6e-68 227.8 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain LON_substr_bdg PF02190.16 PSC68558.1 - 1.5e-25 90.3 0.0 3.2e-25 89.2 0.0 1.6 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA PF00004.29 PSC68558.1 - 2.6e-20 73.2 0.0 7.1e-20 71.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PSC68558.1 - 6.5e-07 29.4 0.0 1.8e-06 28.0 0.0 1.8 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_PrkA PF08298.11 PSC68558.1 - 5.8e-06 25.4 0.0 1.2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 PrkA AAA domain ChlI PF13541.6 PSC68558.1 - 4.7e-05 23.2 0.0 0.00011 22.1 0.0 1.6 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase RuvB_N PF05496.12 PSC68558.1 - 0.0001 22.1 0.0 0.00031 20.5 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PSC68558.1 - 0.0002 21.7 0.4 0.0078 16.5 0.0 3.3 2 2 1 3 3 2 1 AAA domain AAA_2 PF07724.14 PSC68558.1 - 0.00027 21.1 0.0 0.0018 18.4 0.0 2.4 3 0 0 3 3 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 PSC68558.1 - 0.00032 21.1 0.0 0.00032 21.1 0.0 3.9 4 1 1 5 5 4 1 AAA ATPase domain AAA_18 PF13238.6 PSC68558.1 - 0.0096 16.5 0.5 0.028 15.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_23 PF13476.6 PSC68558.1 - 0.011 16.2 3.1 2.2 8.7 0.0 2.5 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 PSC68558.1 - 0.032 14.6 0.0 0.083 13.3 0.0 1.7 1 0 0 1 1 1 0 RNA helicase IstB_IS21 PF01695.17 PSC68558.1 - 0.046 13.4 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Viral_helicase1 PF01443.18 PSC68558.1 - 0.048 13.4 0.0 0.093 12.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 PSC68558.1 - 0.056 13.5 0.0 0.14 12.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PSC68558.1 - 0.088 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 PSC68558.1 - 0.13 12.1 0.0 0.96 9.3 0.0 2.2 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 PSC68558.1 - 0.15 12.0 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase TsaE PF02367.17 PSC68558.1 - 0.16 12.0 0.0 0.5 10.4 0.0 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_15 PF13175.6 PSC68558.1 - 0.2 11.3 0.3 12 5.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain ABC_tran PF00005.27 PSC68558.1 - 0.26 11.8 0.9 0.67 10.5 0.1 2.1 2 0 0 2 2 2 0 ABC transporter SKI PF01202.22 PSC68558.1 - 0.43 10.7 0.0 0.43 10.7 0.0 2.2 3 0 0 3 3 1 0 Shikimate kinase MMS1_N PF10433.9 PSC68559.1 - 2.2e-104 349.8 0.0 3.5e-104 349.2 0.0 1.3 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 PSC68559.1 - 2e-75 254.1 0.0 3.5e-75 253.3 0.0 1.4 1 0 0 1 1 1 1 CPSF A subunit region HMG_box_2 PF09011.10 PSC68560.1 - 7.1e-06 26.5 3.8 7.1e-06 26.5 3.8 2.0 2 1 0 2 2 2 1 HMG-box domain YABBY PF04690.13 PSC68560.1 - 0.00088 19.9 0.6 0.00088 19.9 0.6 2.1 1 1 1 2 2 2 1 YABBY protein HMG_box PF00505.19 PSC68560.1 - 0.016 15.6 4.7 0.16 12.4 4.7 2.3 1 1 0 1 1 1 0 HMG (high mobility group) box NOA36 PF06524.12 PSC68560.1 - 0.069 12.5 2.9 0.093 12.0 2.9 1.2 1 0 0 1 1 1 0 NOA36 protein GP38 PF05268.11 PSC68560.1 - 0.12 12.0 3.8 0.15 11.7 0.5 2.0 2 0 0 2 2 2 0 Phage tail fibre adhesin Gp38 Serglycin PF04360.12 PSC68560.1 - 0.15 12.0 1.5 0.3 11.0 1.5 1.6 1 0 0 1 1 1 0 Serglycin AF-4 PF05110.13 PSC68560.1 - 0.8 7.7 19.4 0.36 8.9 17.7 1.4 1 1 0 1 1 1 0 AF-4 proto-oncoprotein NAD_binding_2 PF03446.15 PSC68561.1 - 3.1e-35 121.7 0.8 5.5e-35 120.9 0.8 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 PSC68561.1 - 7.5e-27 94.0 2.3 7.5e-27 94.0 2.3 1.8 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase adh_short PF00106.25 PSC68561.1 - 0.0093 15.4 0.1 0.093 12.2 0.1 2.3 2 1 0 2 2 2 1 short chain dehydrogenase ApbA PF02558.16 PSC68561.1 - 0.04 13.6 0.0 0.061 13.0 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RE_NgoBV PF09564.10 PSC68561.1 - 0.2 11.1 0.0 0.46 9.9 0.0 1.5 1 1 1 2 2 2 0 NgoBV restriction endonuclease Pkinase PF00069.25 PSC68562.1 - 8.2e-49 166.3 0.0 1.6e-48 165.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC68562.1 - 5.9e-48 163.4 0.0 1.6e-47 162.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 PSC68562.1 - 5.3e-14 52.1 0.9 0.001 19.4 0.0 5.6 4 1 3 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC68562.1 - 8.6e-14 51.1 0.1 0.0014 18.4 0.0 5.1 2 1 3 5 5 5 4 Leucine rich repeat LRRNT_2 PF08263.12 PSC68562.1 - 0.00026 21.2 4.6 0.0019 18.5 0.9 2.8 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 PSC68562.1 - 0.026 15.0 1.4 2.1e+02 3.1 0.0 5.3 6 0 0 6 6 6 0 Leucine Rich Repeat Erv26 PF04148.13 PSC68562.1 - 0.33 10.8 0.0 0.58 9.9 0.0 1.3 1 0 0 1 1 1 0 Transmembrane adaptor Erv26 GDP_Man_Dehyd PF16363.5 PSC68563.1 - 7.2e-43 147.2 0.0 1e-42 146.8 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PSC68563.1 - 2.4e-39 135.2 0.0 3.6e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 PSC68563.1 - 2.7e-12 46.4 0.0 4.1e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 PSC68563.1 - 1.1e-09 37.8 0.0 1.7e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 PSC68563.1 - 2.8e-09 36.5 0.1 2.1e-07 30.4 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein 3Beta_HSD PF01073.19 PSC68563.1 - 3.3e-08 32.9 0.0 1e-07 31.3 0.0 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding PF00501.28 PSC68564.1 - 2.3e-88 296.6 0.0 4.2e-88 295.8 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme TPP_enzyme_N PF02776.18 PSC68564.1 - 1.3e-46 158.3 1.7 1.3e-46 158.3 1.7 3.4 3 1 1 4 4 4 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 PSC68564.1 - 2.9e-27 95.0 1.6 4.8e-27 94.3 0.2 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 PSC68564.1 - 3.2e-27 95.2 0.1 1.2e-26 93.4 0.1 2.1 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain AMP-binding_C PF13193.6 PSC68564.1 - 3.2e-16 60.1 2.7 7.2e-16 58.9 0.6 2.9 4 0 0 4 4 4 1 AMP-binding enzyme C-terminal domain STI1 PF17830.1 PSC68565.1 - 0.15 12.0 0.0 0.41 10.6 0.0 1.7 1 0 0 1 1 1 0 STI1 domain DUF5333 PF17267.2 PSC68565.1 - 0.42 10.8 2.3 0.55 10.4 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5333) zf-4CXXC_R1 PF10497.9 PSC68566.1 - 1.4e-34 118.2 15.6 3e-34 117.2 15.6 1.6 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Fe-ADH PF00465.19 PSC68567.1 - 3.8e-110 368.1 0.1 6.4e-110 367.4 0.1 1.4 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Aldedh PF00171.22 PSC68567.1 - 4e-28 98.2 3.4 1.2e-25 89.9 3.4 2.1 2 0 0 2 2 2 2 Aldehyde dehydrogenase family Fe-ADH_2 PF13685.6 PSC68567.1 - 6.2e-18 65.4 0.2 1.4e-07 31.5 0.4 2.9 3 0 0 3 3 3 2 Iron-containing alcohol dehydrogenase Aldedh PF00171.22 PSC68568.1 - 1.3e-168 561.3 0.0 1.6e-168 561.1 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 PSC68568.1 - 0.00013 21.5 0.0 0.021 14.3 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1487) PGA_cap PF09587.10 PSC68570.1 - 1.2e-61 208.4 0.0 2.5e-61 207.4 0.0 1.5 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap Foie-gras_1 PF11817.8 PSC68570.1 - 6.8e-23 81.6 0.0 1.3e-22 80.7 0.0 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun-like PF12742.7 PSC68570.1 - 0.019 15.0 0.0 0.034 14.2 0.0 1.4 1 0 0 1 1 1 0 Gryzun, putative Golgi trafficking Gryzun PF07919.12 PSC68570.1 - 0.05 12.4 0.0 0.17 10.7 0.0 1.7 2 0 0 2 2 2 0 Gryzun, putative trafficking through Golgi DAGK_cat PF00781.24 PSC68570.1 - 0.079 12.6 0.1 0.26 10.9 0.1 1.9 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain DUF1077 PF06417.12 PSC68571.1 - 2.3e-27 95.4 0.6 2.6e-27 95.2 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) PP2C PF00481.21 PSC68572.1 - 5.1e-40 137.7 0.0 8.5e-40 137.0 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C Methyltransf_22 PF13383.6 PSC68572.1 - 1.2e-39 136.4 0.0 1.6e-39 136.0 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain DUF3181 PF11378.8 PSC68572.1 - 5e-16 58.8 0.0 1e-15 57.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3181) SpoIIE PF07228.12 PSC68572.1 - 1.5e-06 28.3 0.0 0.0014 18.6 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) Methyltransf_21 PF05050.12 PSC68572.1 - 0.0003 20.8 0.0 0.00058 19.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase FkbM domain Fasciclin PF02469.22 PSC68573.1 - 0.0013 19.0 0.0 0.0019 18.4 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Glyco_hydro_47 PF01532.20 PSC68574.1 - 9.6e-113 377.5 0.0 1.4e-112 376.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 PA PF02225.22 PSC68574.1 - 7.3e-12 45.1 0.6 3.2e-11 43.1 0.6 2.2 1 0 0 1 1 1 1 PA domain Aa_trans PF01490.18 PSC68575.1 - 5.1e-22 78.1 4.5 1.9e-21 76.3 5.2 1.5 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein Peptidase_M1 PF01433.20 PSC68575.1 - 4.7e-21 75.4 0.0 2.5e-20 73.0 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 PSC68575.1 - 7.6e-10 39.3 0.0 1.3e-09 38.5 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Trp_Tyr_perm PF03222.13 PSC68575.1 - 0.02 13.9 7.2 0.033 13.2 7.2 1.2 1 0 0 1 1 1 0 Tryptophan/tyrosine permease family rve PF00665.26 PSC68576.1 - 9.1e-19 67.8 0.0 2.1e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Phospholip_A2_1 PF00068.19 PSC68576.1 - 0.00027 21.4 4.2 0.00054 20.4 4.2 1.4 1 0 0 1 1 1 1 Phospholipase A2 rve_3 PF13683.6 PSC68576.1 - 0.0075 16.0 0.0 0.022 14.6 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Asp_protease PF09668.10 PSC68577.1 - 2.9e-54 182.1 0.0 4e-54 181.7 0.0 1.2 1 0 0 1 1 1 1 Aspartyl protease gag-asp_proteas PF13975.6 PSC68577.1 - 9.9e-18 64.5 0.0 1.7e-17 63.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease ubiquitin PF00240.23 PSC68577.1 - 3.2e-12 46.0 0.0 7e-12 44.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family UBA PF00627.31 PSC68577.1 - 8.8e-08 31.9 1.3 1.2e-07 31.5 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain Asp_protease_2 PF13650.6 PSC68577.1 - 2.5e-06 28.0 0.0 5.4e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Aspartyl protease RVP_2 PF08284.11 PSC68577.1 - 0.042 13.6 0.0 0.092 12.5 0.0 1.5 1 1 0 1 1 1 0 Retroviral aspartyl protease Rad60-SLD PF11976.8 PSC68577.1 - 0.044 13.6 0.0 0.077 12.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 PSC68577.1 - 0.084 12.8 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain UBA_4 PF14555.6 PSC68577.1 - 0.088 12.6 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 UBA-like domain HOIP-UBA PF16678.5 PSC68577.1 - 0.1 12.6 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 HOIP UBA domain pair Ribosomal_60s PF00428.19 PSC68577.1 - 3.4 8.3 15.7 3.7 8.2 0.7 3.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein NUDIX PF00293.28 PSC68578.1 - 1.9e-11 44.1 0.0 3.3e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Bcr-Abl_Oligo PF09036.10 PSC68579.1 - 1.4 9.0 11.3 1.3 9.1 0.1 4.4 4 0 0 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain Sec8_exocyst PF04048.14 PSC68579.1 - 5.8 6.8 14.7 1.4 8.8 0.5 4.6 3 1 1 4 4 4 0 Sec8 exocyst complex component specific domain Bcr-Abl_Oligo PF09036.10 PSC68580.1 - 1.4 9.0 11.3 1.3 9.1 0.1 4.4 4 0 0 4 4 4 0 Bcr-Abl oncoprotein oligomerisation domain Sec8_exocyst PF04048.14 PSC68580.1 - 5.8 6.8 14.7 1.4 8.8 0.5 4.6 3 1 1 4 4 4 0 Sec8 exocyst complex component specific domain LETM1 PF07766.13 PSC68581.1 - 1.7e-101 339.1 0.3 3.9e-101 337.9 0.3 1.6 1 0 0 1 1 1 1 LETM1-like protein EF-hand_6 PF13405.6 PSC68581.1 - 8.7e-05 22.2 0.1 0.0049 16.7 0.0 3.1 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 PSC68581.1 - 0.0007 19.0 0.0 0.0007 19.0 0.0 2.5 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 PSC68581.1 - 0.00072 20.0 0.8 0.004 17.6 0.1 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 PSC68581.1 - 0.0043 16.5 0.0 0.0043 16.5 0.0 2.9 4 0 0 4 4 4 1 EF hand SAP PF02037.27 PSC68581.1 - 0.0043 16.8 0.0 0.013 15.3 0.0 1.9 1 0 0 1 1 1 1 SAP domain Peptidase_S39 PF02122.15 PSC68582.1 - 0.14 11.7 0.6 18 4.8 0.0 2.6 1 1 1 2 2 2 0 Peptidase S39 Hamartin PF04388.12 PSC68582.1 - 2.7 6.6 12.8 4.8 5.7 12.8 1.3 1 0 0 1 1 1 0 Hamartin protein PetN PF03742.14 PSC68583.1 - 8.1e-13 48.0 6.3 8.1e-13 48.0 6.3 2.0 2 0 0 2 2 2 1 PetN 12TM_1 PF09847.9 PSC68583.1 - 0.054 12.6 0.0 0.063 12.4 0.0 1.0 1 0 0 1 1 1 0 Membrane protein of 12 TMs Rieske PF00355.26 PSC68584.1 - 1.3e-10 41.0 0.0 2.6e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 PSC68584.1 - 0.0014 18.7 0.0 0.0025 17.9 0.0 1.4 1 0 0 1 1 1 1 Pheophorbide a oxygenase NDK PF00334.19 PSC68585.1 - 5.8e-53 178.5 0.0 7.9e-53 178.1 0.0 1.2 1 0 0 1 1 1 1 Nucleoside diphosphate kinase X PF00739.19 PSC68585.1 - 0.093 12.9 0.6 0.12 12.5 0.6 1.2 1 0 0 1 1 1 0 Trans-activation protein X NYN PF01936.18 PSC68586.1 - 1e-08 35.7 0.0 1.6e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 NYN domain Thioredoxin PF00085.20 PSC68587.1 - 5.5e-12 45.6 0.0 8.2e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 PSC68587.1 - 0.0041 16.9 0.0 0.0064 16.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 PSC68587.1 - 0.0047 17.1 0.9 0.006 16.7 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_4 PF13462.6 PSC68587.1 - 0.024 14.8 0.2 0.39 10.9 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.6 PSC68587.1 - 0.042 14.3 0.5 0.43 11.1 0.5 2.2 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PSC68587.1 - 0.16 12.3 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin PF00085.20 PSC68588.1 - 5.5e-12 45.6 0.0 8e-12 45.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 PSC68588.1 - 0.0033 17.2 0.0 0.0051 16.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 PSC68588.1 - 0.0047 17.1 0.9 0.006 16.7 0.0 1.6 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_4 PF13462.6 PSC68588.1 - 0.024 14.8 0.2 0.39 10.9 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.6 PSC68588.1 - 0.041 14.3 0.5 0.42 11.1 0.5 2.2 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PSC68588.1 - 0.17 12.2 0.0 0.33 11.3 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like UPF1_Zn_bind PF09416.10 PSC68590.1 - 3.9e-60 202.2 0.0 6.5e-60 201.5 0.0 1.4 1 0 0 1 1 1 1 RNA helicase (UPF2 interacting domain) AAA_12 PF13087.6 PSC68590.1 - 7.2e-59 198.8 0.0 1.1e-58 198.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PSC68590.1 - 7.5e-50 170.1 1.2 1.1e-27 97.4 0.0 2.4 1 1 1 2 2 2 2 AAA domain DUF5599 PF18141.1 PSC68590.1 - 2.3e-24 85.4 0.0 4.9e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) PDDEXK_6 PF04720.12 PSC68590.1 - 8.6e-19 68.4 0.0 1.5e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 PDDEXK-like family of unknown function AAA_30 PF13604.6 PSC68590.1 - 1.6e-14 54.1 2.0 6.3e-14 52.1 1.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PSC68590.1 - 1.4e-12 48.2 0.4 4.1e-12 46.7 0.4 1.8 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 PSC68590.1 - 8.7e-06 25.8 0.0 1.6e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_RecD PF05127.14 PSC68590.1 - 0.00013 21.9 0.1 0.00027 20.8 0.1 1.6 1 0 0 1 1 1 1 Helicase DUF2075 PF09848.9 PSC68590.1 - 0.00041 19.7 0.9 0.0023 17.3 0.0 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) PIF1 PF05970.14 PSC68590.1 - 0.00064 19.0 0.0 0.57 9.3 0.0 2.2 2 0 0 2 2 2 2 PIF1-like helicase ATPase PF06745.13 PSC68590.1 - 0.0067 15.8 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_10 PF12846.7 PSC68590.1 - 0.01 14.8 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain DEAD PF00270.29 PSC68590.1 - 0.012 15.4 0.2 0.026 14.3 0.2 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase Ribosomal_S13_N PF08069.12 PSC68590.1 - 0.021 14.8 0.0 0.063 13.3 0.0 1.8 1 0 0 1 1 1 0 Ribosomal S13/S15 N-terminal domain PhoH PF02562.16 PSC68590.1 - 0.028 13.9 0.1 0.1 12.1 0.1 1.8 1 1 1 2 2 2 0 PhoH-like protein AAA_22 PF13401.6 PSC68590.1 - 0.032 14.5 0.0 0.13 12.5 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PSC68590.1 - 0.041 14.3 0.1 0.22 11.9 0.1 2.3 1 0 0 1 1 1 0 AAA ATPase domain Peptidase_S8 PF00082.22 PSC68591.1 - 1.2e-39 136.3 13.3 1.2e-39 136.3 13.3 2.0 2 0 0 2 2 2 1 Subtilase family SET PF00856.28 PSC68591.1 - 7.1e-13 49.3 0.0 3.1e-12 47.2 0.0 2.1 1 1 0 1 1 1 1 SET domain TPR_12 PF13424.6 PSC68591.1 - 0.0082 16.4 1.4 0.028 14.7 1.4 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat zf-MYND PF01753.18 PSC68591.1 - 0.0085 16.2 12.1 0.0085 16.2 12.1 2.5 2 0 0 2 2 2 1 MYND finger Ribosomal_L1 PF00687.21 PSC68592.1 - 5.1e-45 153.7 0.0 6.7e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family DUF4245 PF14030.6 PSC68592.1 - 0.0036 17.3 1.8 0.0061 16.6 1.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4245) DUF2730 PF10805.8 PSC68593.1 - 0.36 11.0 3.4 5 7.3 0.0 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2730) Amidohydro_1 PF01979.20 PSC68594.1 - 2e-10 40.5 0.0 3.2e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Dcc1 PF09724.9 PSC68596.1 - 1.1e-78 264.9 0.0 1.4e-78 264.6 0.0 1.2 1 0 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 DUF2012 PF09430.10 PSC68596.1 - 9.6e-13 48.3 0.0 1.9e-12 47.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) CarboxypepD_reg PF13620.6 PSC68596.1 - 0.0003 21.0 0.0 0.00072 19.8 0.0 1.7 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Pkinase PF00069.25 PSC68597.1 - 1.9e-19 70.1 0.0 4e-19 69.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC68597.1 - 4.9e-18 65.4 0.2 1.2e-17 64.0 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase Cu_amine_oxidN2 PF02727.16 PSC68597.1 - 0.23 11.7 1.3 0.64 10.3 0.0 2.4 2 0 0 2 2 2 0 Copper amine oxidase, N2 domain Transket_pyr PF02779.24 PSC68598.1 - 1.5e-44 151.8 0.0 2.5e-44 151.1 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 PSC68598.1 - 2.1e-18 66.4 0.1 6e-11 42.3 0.0 2.7 2 1 1 3 3 3 2 Transketolase, C-terminal domain VKOR PF07884.14 PSC68598.1 - 0.035 14.3 0.0 0.064 13.4 0.0 1.4 1 0 0 1 1 1 0 Vitamin K epoxide reductase family Nucleotid_trans PF03407.16 PSC68599.1 - 1.3e-23 84.1 0.0 1.9e-23 83.6 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 PSC68599.1 - 0.23 11.2 0.0 0.35 10.5 0.0 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Ank_2 PF12796.7 PSC68600.1 - 6.2e-17 62.0 4.6 7.4e-09 36.1 0.0 4.4 4 2 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC68600.1 - 2.9e-12 46.6 6.6 8e-06 26.0 0.1 4.8 2 1 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC68600.1 - 9.5e-12 44.0 6.9 0.095 13.3 0.0 8.2 8 0 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.6 PSC68600.1 - 1.6e-10 41.3 0.3 0.00028 21.4 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 PSC68600.1 - 2.2e-07 31.0 9.7 0.67 10.5 0.1 6.9 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.6 PSC68602.1 - 0.024 15.2 0.0 0.1 13.2 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Peptidase_C97 PF05903.14 PSC68604.1 - 6.5e-36 123.4 0.0 8.4e-36 123.1 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain SnoaL_2 PF12680.7 PSC68605.1 - 7e-15 55.5 0.3 1.2e-14 54.7 0.3 1.4 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 PSC68605.1 - 1.9e-05 24.5 0.1 3.8e-05 23.5 0.1 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase NTF2 PF02136.20 PSC68605.1 - 0.031 14.8 0.0 0.049 14.2 0.0 1.3 1 0 0 1 1 1 0 Nuclear transport factor 2 (NTF2) domain DUF2358 PF10184.9 PSC68605.1 - 0.11 12.8 0.0 0.18 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2358) Methyltransf_28 PF02636.17 PSC68606.1 - 4.5e-69 233.0 0.0 2.6e-67 227.2 0.0 2.2 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase BAT2_N PF07001.11 PSC68606.1 - 0.28 11.6 7.7 4.8 7.6 0.3 2.2 2 0 0 2 2 2 0 BAT2 N-terminus Spt20 PF12090.8 PSC68606.1 - 1.5 8.4 11.1 2.2 7.8 11.1 1.1 1 0 0 1 1 1 0 Spt20 family Aa_trans PF01490.18 PSC68607.1 - 2.5e-30 105.5 24.8 3.5e-30 105.0 24.8 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Peptidase_S8 PF00082.22 PSC68607.1 - 6.4e-24 84.7 11.3 1.8e-23 83.2 11.3 1.6 1 1 1 2 2 2 1 Subtilase family rve PF00665.26 PSC68607.1 - 2.5e-18 66.4 0.0 5.6e-18 65.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC68607.1 - 0.0079 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Pex24p PF06398.11 PSC68607.1 - 0.1 11.5 0.3 0.22 10.4 0.3 1.4 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin EF-1_beta_acid PF10587.9 PSC68608.1 - 0.0057 17.1 2.9 0.059 13.8 0.6 3.1 2 0 0 2 2 2 1 Eukaryotic elongation factor 1 beta central acidic region Thioredoxin PF00085.20 PSC68608.1 - 0.047 13.7 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin ABC2_membrane PF01061.24 PSC68609.1 - 1e-31 110.0 23.5 1.4e-31 109.6 23.5 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PSC68609.1 - 1.1e-27 97.2 0.5 6e-27 94.8 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 PSC68609.1 - 3.2e-08 33.8 0.0 0.0025 17.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 PSC68609.1 - 9e-07 28.3 11.9 1.2e-06 27.9 11.9 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 PSC68609.1 - 0.0034 17.3 0.3 0.007 16.3 0.1 1.6 1 1 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 PSC68609.1 - 0.0043 17.3 0.1 0.017 15.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain SMC_N PF02463.19 PSC68609.1 - 0.011 15.2 0.0 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 PSC68609.1 - 0.013 15.1 0.0 0.05 13.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 PSC68609.1 - 0.018 15.4 0.1 0.018 15.4 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 PSC68609.1 - 0.029 13.6 0.2 0.069 12.3 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain AAA_29 PF13555.6 PSC68609.1 - 0.042 13.6 0.2 0.042 13.6 0.2 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain Rad17 PF03215.15 PSC68609.1 - 0.082 12.8 0.0 0.34 10.8 0.0 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_24 PF13479.6 PSC68609.1 - 0.11 12.2 0.1 0.31 10.7 0.1 1.7 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 PSC68609.1 - 0.14 12.4 0.4 1.1 9.5 0.0 2.5 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit IstB_IS21 PF01695.17 PSC68609.1 - 0.2 11.4 0.1 2.2 8.0 0.0 2.5 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_18 PF13238.6 PSC68609.1 - 0.21 12.1 0.0 0.41 11.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Rhabdo_NV PF02484.15 PSC68610.1 - 0.031 14.4 0.0 0.5 10.5 0.0 2.0 2 0 0 2 2 2 0 Rhabdovirus Non-virion protein SAP30_Sin3_bdg PF13867.6 PSC68611.1 - 8.3e-12 45.3 0.2 1.9e-11 44.1 0.2 1.6 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 DUF2336 PF10098.9 PSC68611.1 - 0.00079 19.0 5.1 0.0011 18.5 5.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein conserved in bacteria (DUF2336) Fuseless PF15993.5 PSC68611.1 - 0.0012 18.1 0.0 0.0019 17.5 0.0 1.3 1 0 0 1 1 1 1 Fuseless ImcF-related_N PF14331.6 PSC68611.1 - 0.034 13.5 1.4 0.087 12.2 0.8 1.8 1 1 1 2 2 2 0 ImcF-related N-terminal domain ATF7IP_BD PF16788.5 PSC68611.1 - 0.13 12.4 0.3 0.13 12.4 0.3 1.5 2 0 0 2 2 2 0 ATF-interacting protein binding domain HSCB_C PF07743.13 PSC68611.1 - 0.24 11.9 4.1 0.94 10.0 4.1 2.0 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain POTRA_TamA_1 PF17243.2 PSC68611.1 - 0.41 10.8 2.3 0.54 10.4 0.8 2.0 2 1 0 2 2 2 0 POTRA domain TamA domain 1 PSK_trans_fac PF07704.11 PSC68611.1 - 0.65 10.8 5.9 1.2 10.0 3.5 2.5 2 1 0 2 2 2 0 Rv0623-like transcription factor PCNA_N PF00705.18 PSC68612.1 - 5.5e-59 197.4 3.5 1e-58 196.6 3.5 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 PSC68612.1 - 2.3e-53 179.8 0.1 4.8e-53 178.7 0.0 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 PSC68612.1 - 1.7e-07 30.6 0.6 8.5e-07 28.3 0.6 1.9 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 PSC68612.1 - 1e-06 28.4 0.3 1.1e-06 28.3 0.3 1.1 1 0 0 1 1 1 1 Rad9 Hus1 PF04005.12 PSC68612.1 - 0.0017 17.5 0.0 0.088 11.9 0.0 2.1 1 1 1 2 2 2 2 Hus1-like protein Regulator_TrmB PF11495.8 PSC68612.1 - 0.11 11.6 0.0 0.4 9.8 0.0 1.8 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB Fuseless PF15993.5 PSC68613.1 - 7.3e-10 38.5 0.5 9.2e-10 38.2 0.5 1.0 1 0 0 1 1 1 1 Fuseless Asp23 PF03780.13 PSC68613.1 - 0.083 13.3 4.0 0.17 12.3 4.0 1.6 1 1 0 1 1 1 0 Asp23 family, cell envelope-related function YjeJ PF15922.5 PSC68613.1 - 0.11 11.7 0.3 0.16 11.2 0.3 1.2 1 0 0 1 1 1 0 YjeJ-like Myc_target_1 PF15179.6 PSC68613.1 - 0.12 12.2 1.6 4.1 7.3 0.1 2.2 2 0 0 2 2 2 0 Myc target protein 1 EIIA-man PF03610.16 PSC68613.1 - 0.63 10.3 5.7 1.1 9.5 0.2 2.5 2 1 0 2 2 2 0 PTS system fructose IIA component CopD PF05425.13 PSC68613.1 - 2.5 8.5 9.2 0.25 11.8 3.5 2.0 2 1 0 2 2 2 0 Copper resistance protein D Cupin_2 PF07883.11 PSC68614.1 - 4.8e-15 55.0 0.2 4.8e-15 55.0 0.2 1.4 2 0 0 2 2 2 1 Cupin domain Cupin_3 PF05899.12 PSC68614.1 - 7e-06 25.6 0.4 1.2e-05 25.0 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF861) AraC_binding PF02311.19 PSC68614.1 - 0.00012 22.0 0.0 0.00015 21.7 0.0 1.2 1 0 0 1 1 1 1 AraC-like ligand binding domain EutQ PF06249.12 PSC68614.1 - 0.00058 19.6 0.0 0.00078 19.2 0.0 1.1 1 0 0 1 1 1 1 Ethanolamine utilisation protein EutQ MannoseP_isomer PF01050.18 PSC68614.1 - 0.001 18.9 0.0 0.0013 18.6 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate isomerase JmjC PF02373.22 PSC68614.1 - 0.0026 18.2 0.1 0.021 15.2 0.0 2.1 2 1 1 3 3 3 1 JmjC domain, hydroxylase CENP-C_C PF11699.8 PSC68614.1 - 0.0034 17.6 0.0 0.0048 17.1 0.0 1.2 1 0 0 1 1 1 1 Mif2/CENP-C like ARD PF03079.14 PSC68614.1 - 0.021 15.0 0.0 0.036 14.3 0.0 1.4 1 0 0 1 1 1 0 ARD/ARD' family DMSP_lyase PF16867.5 PSC68614.1 - 0.045 13.4 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Dimethlysulfonioproprionate lyase Cupin_1 PF00190.22 PSC68614.1 - 0.16 11.6 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Cupin COPI_C PF06957.11 PSC68617.1 - 6.5e-162 538.9 0.0 8.3e-162 538.5 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 PSC68617.1 - 1.3e-125 420.0 0.0 2.3e-125 419.2 0.0 1.4 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 PSC68617.1 - 7.6e-44 146.8 18.1 2.7e-08 34.3 0.1 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC68617.1 - 1.6e-09 37.9 0.9 0.0021 18.3 0.0 5.7 3 2 3 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_1 PF00515.28 PSC68617.1 - 0.0035 17.1 0.0 2.7 8.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 PSC68617.1 - 0.0098 15.9 0.0 32 5.0 0.1 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat BPL_LplA_LipB_2 PF16917.5 PSC68617.1 - 0.024 14.2 0.0 0.097 12.2 0.0 2.0 1 0 0 1 1 1 0 Biotin/lipoate A/B protein ligase family Fis1_TPR_C PF14853.6 PSC68617.1 - 0.033 14.3 0.0 0.55 10.3 0.0 2.5 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat Nup160 PF11715.8 PSC68617.1 - 0.25 9.9 7.3 3.8 6.0 0.0 3.5 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Mago-bind PF09282.10 PSC68618.1 - 6.4e-14 51.5 4.6 1.1e-13 50.7 4.6 1.4 1 0 0 1 1 1 1 Mago binding FAM199X PF15814.5 PSC68618.1 - 0.38 9.8 2.8 0.5 9.4 2.8 1.1 1 0 0 1 1 1 0 Protein family FAM199X Mago-bind PF09282.10 PSC68619.1 - 6.4e-14 51.5 4.6 1.1e-13 50.7 4.6 1.4 1 0 0 1 1 1 1 Mago binding FAM199X PF15814.5 PSC68619.1 - 0.38 9.8 2.8 0.5 9.4 2.8 1.1 1 0 0 1 1 1 0 Protein family FAM199X CBS PF00571.28 PSC68621.1 - 9.1e-51 170.1 1.3 3.6e-15 56.1 0.1 4.3 4 0 0 4 4 4 4 CBS domain YtxH PF12732.7 PSC68621.1 - 0.039 14.5 2.6 0.13 12.8 2.6 1.9 1 0 0 1 1 1 0 YtxH-like protein Apolipoprotein PF01442.18 PSC68621.1 - 0.1 12.5 1.6 0.18 11.6 1.6 1.4 1 0 0 1 1 1 0 Apolipoprotein A1/A4/E domain PRC PF05239.16 PSC68621.1 - 0.11 12.7 3.3 13 5.9 0.1 3.4 4 0 0 4 4 4 0 PRC-barrel domain sCache_3_2 PF17203.4 PSC68621.1 - 1.1 9.4 6.9 8.6 6.5 0.0 4.0 4 1 0 4 4 4 0 Single cache domain 3 rve PF00665.26 PSC68622.1 - 8.3e-19 67.9 0.0 1.8e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC68622.1 - 0.0066 16.2 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Alpha-amylase PF00128.24 PSC68623.1 - 1.4e-31 110.4 0.0 4.1e-31 108.8 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glycos_transf_1 PF00534.20 PSC68623.1 - 2.9e-08 33.4 0.0 5.9e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Gaa1 PF04114.14 PSC68624.1 - 2.8e-37 128.9 0.0 1.3e-36 126.7 0.0 2.0 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component Fasciclin PF02469.22 PSC68624.1 - 1e-06 29.0 0.0 1.8e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain MukF_M PF17192.4 PSC68625.1 - 0.0034 17.2 0.0 0.012 15.4 0.0 1.9 1 0 0 1 1 1 1 MukF middle domain DUF4770 PF15994.5 PSC68625.1 - 6 7.1 12.2 8.1 6.6 2.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) MMR_HSR1 PF01926.23 PSC68627.1 - 1.7e-19 70.0 0.0 3e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PWWP PF00855.17 PSC68627.1 - 1.7e-15 57.2 0.6 8.5e-15 54.9 0.4 2.3 2 0 0 2 2 2 1 PWWP domain FeoB_N PF02421.18 PSC68627.1 - 1.2e-08 34.6 0.0 1.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PSC68627.1 - 5e-05 23.3 0.0 0.0047 16.8 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 PSC68627.1 - 0.0013 18.8 0.2 0.017 15.2 0.3 2.3 1 1 1 2 2 2 1 Dynamin family ABC_tran PF00005.27 PSC68627.1 - 0.47 11.0 1.9 1.7 9.1 0.0 2.6 3 0 0 3 3 3 0 ABC transporter MMR_HSR1 PF01926.23 PSC68628.1 - 1.7e-19 70.0 0.0 3e-19 69.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase PWWP PF00855.17 PSC68628.1 - 1.7e-15 57.2 0.6 8.5e-15 54.9 0.4 2.3 2 0 0 2 2 2 1 PWWP domain FeoB_N PF02421.18 PSC68628.1 - 1.2e-08 34.6 0.0 1.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PSC68628.1 - 5e-05 23.3 0.0 0.0047 16.9 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 PSC68628.1 - 0.0013 18.9 0.2 0.017 15.2 0.3 2.3 1 1 1 2 2 2 1 Dynamin family ABC_tran PF00005.27 PSC68628.1 - 0.3 11.6 0.8 1.7 9.1 0.0 2.4 3 0 0 3 3 3 0 ABC transporter Hydrolase_4 PF12146.8 PSC68629.1 - 6.2e-54 182.8 0.0 9.5e-54 182.2 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 ABC2_membrane PF01061.24 PSC68629.1 - 2.4e-34 118.6 16.0 3.9e-34 117.9 16.0 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PSC68629.1 - 2.9e-08 34.3 0.0 3.4e-07 30.9 0.0 2.2 1 1 1 2 2 2 1 ABC transporter Abhydrolase_1 PF00561.20 PSC68629.1 - 0.0003 20.5 0.6 0.0024 17.6 0.5 2.2 2 0 0 2 2 2 1 alpha/beta hydrolase fold ABC2_membrane_3 PF12698.7 PSC68629.1 - 0.5 9.4 14.8 0.57 9.2 14.0 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Glutaredoxin PF00462.24 PSC68630.1 - 8.7e-37 125.2 0.0 2.1e-16 59.8 0.0 3.4 3 0 0 3 3 3 3 Glutaredoxin Thioredoxin PF00085.20 PSC68630.1 - 5e-17 61.8 0.0 1.2e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PSC68630.1 - 2.5e-05 24.7 0.1 0.0002 21.8 0.0 2.5 3 1 0 3 3 3 1 Thioredoxin-like domain HyaE PF07449.11 PSC68630.1 - 0.0014 18.6 0.1 0.012 15.6 0.0 2.5 3 0 0 3 3 3 1 Hydrogenase-1 expression protein HyaE Thioredoxin_7 PF13899.6 PSC68630.1 - 0.027 14.6 0.9 0.3 11.3 0.2 2.7 3 0 0 3 3 3 0 Thioredoxin-like DIM1 PF02966.16 PSC68630.1 - 0.094 12.5 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Mitosis protein DIM1 GST_N_3 PF13417.6 PSC68630.1 - 0.1 13.0 0.0 0.81 10.1 0.0 2.1 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain DOT1 PF08123.13 PSC68631.1 - 0.15 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 PDZ_3 PF17815.1 PSC68632.1 - 2e-10 40.7 2.1 1.4e-09 38.0 0.0 2.1 2 0 0 2 2 2 1 PDZ domain Tox-GHH PF15636.6 PSC68632.1 - 0.00056 19.8 5.0 1.7 8.7 0.0 2.5 2 0 0 2 2 2 2 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF2368 PF10166.9 PSC68632.1 - 0.63 9.7 9.2 0.96 9.1 9.2 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) FTZ PF03867.14 PSC68632.1 - 1.1 8.8 4.0 1.4 8.4 4.0 1.1 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region TFIIA PF03153.13 PSC68632.1 - 2.9 7.8 11.7 3.4 7.5 11.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BRF1 PF07741.13 PSC68632.1 - 9.8 6.6 8.6 13 6.1 8.6 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Amidase PF01425.21 PSC68633.1 - 5.1e-67 226.8 1.3 2e-55 188.6 3.1 2.0 2 0 0 2 2 2 2 Amidase DUF3611 PF12263.8 PSC68634.1 - 3.9e-49 166.9 11.8 5.2e-49 166.5 11.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) PBP_N PF17093.5 PSC68634.1 - 0.002 18.4 0.3 0.0037 17.5 0.3 1.5 1 0 0 1 1 1 1 Penicillin-binding protein N-terminus PPR_3 PF13812.6 PSC68635.1 - 7.6e-31 106.0 0.0 7e-12 45.2 0.0 6.7 7 1 1 8 8 8 4 Pentatricopeptide repeat domain PPR_2 PF13041.6 PSC68635.1 - 3.1e-29 100.9 0.0 1.6e-06 28.2 0.0 8.6 7 2 3 10 10 10 5 PPR repeat family PPR_long PF17177.4 PSC68635.1 - 3.1e-15 56.1 0.6 5.3e-05 22.7 0.0 3.6 3 0 0 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 PSC68635.1 - 5.6e-15 54.8 0.0 0.025 14.3 0.0 8.6 9 0 0 9 9 9 5 PPR repeat PPR PF01535.20 PSC68635.1 - 1.4e-14 53.2 1.8 0.0086 16.3 0.0 10.2 11 0 0 11 11 11 2 PPR repeat Lipase_GDSL_2 PF13472.6 PSC68635.1 - 6.8e-12 46.1 0.0 6.8e-12 46.1 0.0 3.9 4 0 0 4 4 4 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 PSC68635.1 - 5.6e-10 39.5 0.0 1.1e-09 38.6 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase ELYS PF13934.6 PSC68635.1 - 1.3 9.0 3.6 0.51 10.3 0.4 1.9 2 0 0 2 2 2 0 Nuclear pore complex assembly VDE PF07137.11 PSC68636.1 - 4.6e-36 124.5 0.0 9.2e-36 123.6 0.0 1.5 1 1 0 1 1 1 1 VDE lipocalin domain Lustrin_cystein PF14625.6 PSC68637.1 - 0.038 14.4 2.4 0.038 14.4 2.4 2.2 2 0 0 2 2 2 0 Lustrin, cysteine-rich repeated domain SnoaL_3 PF13474.6 PSC68639.1 - 6.5e-22 78.1 0.3 1.9e-21 76.6 0.0 1.7 2 0 0 2 2 2 1 SnoaL-like domain UVR PF02151.19 PSC68639.1 - 1e-08 34.6 1.7 1.7e-08 33.9 1.7 1.3 1 0 0 1 1 1 1 UvrB/uvrC motif DUF4440 PF14534.6 PSC68639.1 - 1.7e-07 31.6 1.1 1.5e-06 28.6 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4440) SnoaL_2 PF12680.7 PSC68639.1 - 1.9e-06 28.5 0.4 3.9e-06 27.4 0.0 1.6 2 0 0 2 2 2 1 SnoaL-like domain DUF4403 PF14356.6 PSC68639.1 - 0.021 13.5 0.1 4.5 5.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4403) CaMKII_AD PF08332.10 PSC68639.1 - 0.067 13.3 0.0 0.32 11.1 0.0 2.0 2 0 0 2 2 2 0 Calcium/calmodulin dependent protein kinase II association domain L27 PF02828.16 PSC68639.1 - 0.14 12.0 0.1 0.27 11.0 0.1 1.5 1 0 0 1 1 1 0 L27 domain FmiP_Thoc5 PF09766.9 PSC68643.1 - 5.3e-29 101.6 0.0 6.8e-29 101.3 0.0 1.1 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 AhpC-TSA PF00578.21 PSC68643.1 - 2.6e-08 33.8 0.0 2.1e-07 30.9 0.0 2.1 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PSC68643.1 - 8.3e-05 22.3 0.0 0.0002 21.1 0.0 1.7 1 1 0 1 1 1 1 Redoxin CC2-LZ PF16516.5 PSC68643.1 - 0.077 13.4 0.1 0.18 12.2 0.1 1.5 1 0 0 1 1 1 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Sdh5 PF03937.16 PSC68645.1 - 1.5e-18 66.5 0.3 2.2e-18 66.0 0.3 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase NPBW PF15180.6 PSC68645.1 - 0.088 12.7 0.3 0.16 11.8 0.3 1.4 1 0 0 1 1 1 0 Neuropeptides B and W PSII_Pbs27 PF13326.6 PSC68646.1 - 4.4e-20 72.4 1.2 6.7e-20 71.9 1.2 1.3 1 1 0 1 1 1 1 Photosystem II Pbs27 SURF6 PF04935.12 PSC68647.1 - 9.1e-26 90.9 70.0 9.1e-26 90.9 70.0 2.5 1 1 1 2 2 2 1 Surfeit locus protein 6 RRP14 PF15459.6 PSC68647.1 - 3.4e-15 56.4 0.7 3.4e-15 56.4 0.7 7.5 5 1 0 5 5 5 1 60S ribosome biogenesis protein Rrp14 AF-4 PF05110.13 PSC68647.1 - 0.13 10.4 37.3 0.16 10.0 37.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein rve PF00665.26 PSC68649.1 - 8.3e-19 67.9 0.0 1.8e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC68649.1 - 0.0065 16.2 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Amidohydro_1 PF01979.20 PSC68650.1 - 1.5e-41 142.9 0.0 2.4e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 PSC68650.1 - 3.9e-14 53.0 4.2 1.8e-06 27.7 0.6 2.7 3 0 0 3 3 3 2 Amidohydrolase family Glycos_transf_1 PF00534.20 PSC68650.1 - 0.0013 18.3 0.0 0.0031 17.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 SUIM_assoc PF16619.5 PSC68651.1 - 9.4 6.4 52.6 0.048 13.7 2.8 5.8 5 1 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 RVT_2 PF07727.14 PSC68653.1 - 1.2e-70 238.0 0.0 1.8e-70 237.3 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 PSC68653.1 - 6.7e-31 107.5 0.0 1.6e-27 96.5 0.0 3.2 2 1 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 PSC68653.1 - 4.4e-24 84.7 0.0 8.8e-24 83.7 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 PSC68653.1 - 4.5e-24 84.9 0.0 1.6e-23 83.1 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 PSC68653.1 - 3.9e-09 36.2 0.0 8.2e-09 35.2 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4219 PF13961.6 PSC68653.1 - 5.5e-05 22.7 0.0 0.00013 21.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) rve_3 PF13683.6 PSC68653.1 - 0.00017 21.3 0.0 0.00053 19.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain zf-C2H2_10 PF16588.5 PSC68653.1 - 0.18 11.5 2.0 0.41 10.4 2.0 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_5 PF14787.6 PSC68653.1 - 3.1 7.6 6.1 3.1 7.6 3.7 2.3 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger DUF4173 PF13777.6 PSC68654.1 - 0.32 10.4 4.6 0.14 11.6 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4173) TPR_1 PF00515.28 PSC68655.1 - 2e-09 36.9 12.7 0.00023 20.9 0.7 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PSC68655.1 - 5.9e-09 35.4 31.1 0.0002 21.2 1.5 4.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 PSC68655.1 - 0.0021 18.2 7.1 0.0084 16.3 0.1 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PSC68655.1 - 0.0074 16.3 5.2 0.16 12.1 0.2 2.8 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat CheX PF13690.6 PSC68655.1 - 0.059 13.5 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Chemotaxis phosphatase CheX TPR_6 PF13174.6 PSC68655.1 - 0.089 13.5 0.2 0.089 13.5 0.2 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 PSC68655.1 - 0.096 13.1 4.9 9.8 6.8 0.9 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 PSC68655.1 - 0.31 10.7 14.6 0.14 11.8 5.6 3.3 1 1 2 3 3 3 0 TPR repeat TPR_7 PF13176.6 PSC68655.1 - 0.59 10.3 11.3 1.4 9.2 0.6 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat NIR_SIR PF01077.22 PSC68656.1 - 3e-58 195.8 0.0 1.4e-48 164.4 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 PSC68656.1 - 3.8e-28 97.1 0.2 4.7e-15 55.2 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain NIR_SIR PF01077.22 PSC68657.1 - 3e-58 195.8 0.0 1.4e-48 164.4 0.0 2.3 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 PSC68657.1 - 3.8e-28 97.1 0.2 4.7e-15 55.2 0.0 2.5 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain UPF0004 PF00919.20 PSC68658.1 - 4.9e-28 97.1 0.0 9.7e-28 96.1 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 PSC68658.1 - 2.9e-26 92.8 0.0 6.3e-26 91.7 0.0 1.6 1 1 0 1 1 1 1 Radical SAM superfamily TRAM PF01938.20 PSC68658.1 - 6.5e-07 29.2 0.0 5.8e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 TRAM domain RVT_2 PF07727.14 PSC68659.1 - 1.2e-73 247.8 0.0 1.6e-73 247.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PSC68659.1 - 3.1e-24 85.4 0.0 1.1e-23 83.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Retrotran_gag_2 PF14223.6 PSC68659.1 - 4.1e-24 84.8 0.0 8e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 PSC68659.1 - 4.6e-09 36.0 0.0 1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4219 PF13961.6 PSC68659.1 - 4.3e-05 23.1 0.0 8.7e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) rve_3 PF13683.6 PSC68659.1 - 0.00012 21.7 0.0 0.00037 20.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Retrotran_gag_3 PF14244.6 PSC68659.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-C2H2_10 PF16588.5 PSC68659.1 - 0.15 11.9 2.0 0.28 10.9 2.0 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_3 PF13917.6 PSC68659.1 - 0.15 12.1 0.3 0.39 10.7 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle Crr6 PF08847.11 PSC68659.1 - 0.19 11.4 0.0 0.39 10.4 0.0 1.4 1 0 0 1 1 1 0 Chlororespiratory reduction 6 zf-CCHC_5 PF14787.6 PSC68659.1 - 0.31 10.8 2.5 0.89 9.3 2.5 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger NICE-1 PF15845.5 PSC68660.1 - 0.85 10.4 11.4 1.5 9.7 10.5 2.0 1 1 0 1 1 1 0 Cysteine-rich C-terminal 1 family PIP5K PF01504.18 PSC68666.1 - 1.4e-37 129.4 0.0 1e-28 100.4 0.0 3.0 2 1 1 3 3 3 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 PSC68666.1 - 2.8e-18 65.8 0.0 2.4e-13 49.6 0.0 2.6 2 1 0 2 2 2 2 TCP-1/cpn60 chaperonin family Cyt-b5 PF00173.28 PSC68667.1 - 8.9e-13 48.2 0.0 1.7e-12 47.3 0.0 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain SUIM_assoc PF16619.5 PSC68667.1 - 0.029 14.5 4.4 0.031 14.3 4.4 1.4 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 RAM PF15320.6 PSC68670.1 - 0.017 15.7 1.0 0.017 15.7 1.0 2.3 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein RAM PF15320.6 PSC68671.1 - 0.017 15.7 1.0 0.017 15.7 1.0 2.3 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein Rad10 PF03834.14 PSC68672.1 - 3e-44 149.7 0.0 4.5e-44 149.1 0.0 1.3 1 0 0 1 1 1 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_2 PF12826.7 PSC68672.1 - 2.5e-06 27.5 0.0 4.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.23 PSC68672.1 - 3.2e-06 26.7 0.0 6.7e-06 25.7 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 PSC68672.1 - 2.7e-05 24.7 0.0 5.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain TPR_1 PF00515.28 PSC68674.1 - 2.9e-24 83.8 17.9 4.4e-05 23.1 0.1 7.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 PSC68674.1 - 1.6e-18 66.1 9.5 3.3e-07 29.9 0.5 7.0 2 2 4 6 6 6 6 TPR repeat TPR_2 PF07719.17 PSC68674.1 - 3.8e-17 60.9 51.8 2.1e-05 24.3 0.5 12.0 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 PSC68674.1 - 6.8e-17 60.2 16.5 0.0039 17.3 0.3 10.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 PSC68674.1 - 2.3e-13 49.5 5.3 0.0015 18.8 0.1 6.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 PSC68674.1 - 4.4e-08 32.6 6.7 0.18 11.9 0.0 6.4 5 1 0 5 5 5 2 Tetratricopeptide repeat EF-hand_1 PF00036.32 PSC68674.1 - 0.11 12.1 0.0 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 PSC68674.1 - 0.11 12.4 0.0 0.52 10.4 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain TPR_1 PF00515.28 PSC68675.1 - 2.9e-24 83.8 17.9 4.4e-05 23.1 0.1 7.8 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 PSC68675.1 - 1.6e-18 66.1 9.5 3.3e-07 29.9 0.5 7.0 2 2 4 6 6 6 6 TPR repeat TPR_2 PF07719.17 PSC68675.1 - 3.8e-17 61.0 51.8 2.1e-05 24.3 0.5 12.0 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_8 PF13181.6 PSC68675.1 - 6.7e-17 60.2 16.5 0.0039 17.3 0.3 10.1 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 PSC68675.1 - 2.2e-13 49.5 5.3 0.0015 18.8 0.1 6.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.6 PSC68675.1 - 4.4e-08 32.6 6.7 0.18 11.9 0.0 6.4 5 1 0 5 5 5 2 Tetratricopeptide repeat EF-hand_1 PF00036.32 PSC68675.1 - 0.11 12.1 0.0 0.42 10.3 0.0 2.0 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 PSC68675.1 - 0.12 12.4 0.0 0.52 10.4 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain NHL PF01436.21 PSC68676.1 - 3.3e-29 99.4 0.0 3.4e-05 23.6 0.0 6.9 6 0 0 6 6 6 6 NHL repeat HAD_2 PF13419.6 PSC68676.1 - 1.8e-22 80.3 0.0 2.8e-22 79.7 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase rve PF00665.26 PSC68676.1 - 2.6e-18 66.3 0.0 6.9e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Hydrolase PF00702.26 PSC68676.1 - 9.3e-15 55.5 1.9 1.3e-13 51.7 1.9 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Thioredoxin_8 PF13905.6 PSC68676.1 - 8.7e-11 42.0 0.0 1.5e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like SGL PF08450.12 PSC68676.1 - 1.4e-07 31.4 0.0 0.18 11.3 0.0 3.4 2 1 0 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region Hydrolase_like PF13242.6 PSC68676.1 - 2.4e-07 30.7 0.0 8.1e-07 29.0 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like Redoxin PF08534.10 PSC68676.1 - 0.00065 19.4 0.0 0.0019 17.9 0.0 1.7 1 0 0 1 1 1 1 Redoxin Arylesterase PF01731.20 PSC68676.1 - 0.0027 17.9 0.0 5.3 7.3 0.0 2.8 2 0 0 2 2 2 2 Arylesterase SUIM_assoc PF16619.5 PSC68676.1 - 0.0077 16.3 0.1 0.016 15.2 0.1 1.5 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 ubiquitin PF00240.23 PSC68676.1 - 0.01 15.6 0.0 0.034 13.9 0.0 1.8 2 0 0 2 2 2 0 Ubiquitin family rve_3 PF13683.6 PSC68676.1 - 0.025 14.3 0.0 0.06 13.1 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Thioredoxin PF00085.20 PSC68676.1 - 0.1 12.6 3.1 0.28 11.2 0.1 2.9 4 0 0 4 4 3 0 Thioredoxin SR-25 PF10500.9 PSC68676.1 - 9.6 5.7 5.8 1.9 8.1 1.3 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein AICARFT_IMPCHas PF01808.18 PSC68677.1 - 3.6e-107 358.2 0.0 4.6e-107 357.9 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 PSC68677.1 - 1.3e-23 83.0 0.0 3.2e-23 81.7 0.0 1.7 1 0 0 1 1 1 1 MGS-like domain LapA_dom PF06305.11 PSC68678.1 - 2.9 7.8 6.0 0.54 10.1 1.4 2.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF2834 PF11196.8 PSC68679.1 - 0.6 10.5 5.0 0.18 12.2 0.3 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2834) MgtE PF01769.16 PSC68680.1 - 6e-26 91.3 7.8 1.6e-25 89.8 6.9 1.8 2 0 0 2 2 2 1 Divalent cation transporter Coilin_N PF15862.5 PSC68681.1 - 0.00021 21.1 1.9 0.00021 21.1 1.9 3.2 3 1 0 3 3 3 1 Coilin N-terminus DUF2052 PF09747.9 PSC68681.1 - 6 6.9 34.8 1.9 8.5 3.1 3.4 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) BSP_II PF05432.11 PSC68681.1 - 8 6.1 31.7 1 9.0 0.7 2.8 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) Pex14_N PF04695.13 PSC68682.1 - 0.61 10.7 5.6 1 10.0 5.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Furin-like_2 PF15913.5 PSC68682.1 - 1.8 8.7 34.1 4.7 7.4 17.2 2.9 1 1 1 2 2 2 0 Furin-like repeat, cysteine-rich CBM_14 PF01607.24 PSC68683.1 - 1.9e-17 63.1 20.4 6e-10 39.1 5.8 3.2 3 1 1 4 4 4 2 Chitin binding Peritrophin-A domain Glyco_hydro_18 PF00704.28 PSC68683.1 - 4.5e-17 62.7 0.0 6e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Somatostatin PF03002.15 PSC68683.1 - 0.22 11.5 5.3 6.8 6.7 0.6 2.7 2 0 0 2 2 2 0 Somatostatin/Cortistatin family LON_substr_bdg PF02190.16 PSC68684.1 - 1.3e-07 31.7 0.0 8.9e-05 22.5 0.0 2.5 2 0 0 2 2 2 2 ATP-dependent protease La (LON) substrate-binding domain Yippee-Mis18 PF03226.14 PSC68684.1 - 8.8e-07 29.1 0.0 1.5e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF4101 PF13355.6 PSC68685.1 - 3.7e-09 37.1 6.2 3.4e-05 24.3 0.1 2.6 2 1 1 3 3 3 2 Protein of unknown function (DUF4101) TFIIA PF03153.13 PSC68685.1 - 0.46 10.4 13.5 0.72 9.8 13.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EamA PF00892.20 PSC68685.1 - 1.3 9.2 40.0 1.1 9.4 0.1 5.7 4 2 1 5 5 5 0 EamA-like transporter family DUF4746 PF15928.5 PSC68685.1 - 2.2 7.6 4.5 3.5 7.0 4.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Calpain_inhib PF00748.19 PSC68685.1 - 6.5 7.3 11.4 16 6.0 11.4 1.5 1 0 0 1 1 1 0 Calpain inhibitor MMR1 PF08505.10 PSC68685.1 - 6.7 6.9 6.9 10 6.3 6.9 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein IER PF05760.12 PSC68685.1 - 7.1 6.8 13.1 13 6.0 13.1 1.3 1 0 0 1 1 1 0 Immediate early response protein (IER) Xan_ur_permease PF00860.20 PSC68687.1 - 4.2e-60 203.5 35.6 3e-38 131.5 17.1 2.3 1 1 1 2 2 2 2 Permease family Asp_protease_2 PF13650.6 PSC68687.1 - 4.9e-13 49.5 0.2 2.7e-09 37.5 0.2 2.9 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 PSC68687.1 - 3.3e-07 30.8 0.1 0.0022 18.5 0.0 3.3 4 0 0 4 4 4 2 gag-polyprotein putative aspartyl protease Xan_ur_permease PF00860.20 PSC68688.1 - 4.2e-60 203.5 35.6 3e-38 131.5 17.1 2.3 1 1 1 2 2 2 2 Permease family Asp_protease_2 PF13650.6 PSC68688.1 - 4.9e-13 49.5 0.2 2.7e-09 37.5 0.2 2.9 2 0 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 PSC68688.1 - 3.3e-07 30.8 0.1 0.0022 18.5 0.0 3.3 4 0 0 4 4 4 2 gag-polyprotein putative aspartyl protease Epimerase PF01370.21 PSC68689.1 - 2.6e-20 72.9 0.5 9.6e-20 71.1 0.5 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PSC68689.1 - 1.5e-16 60.2 0.0 2e-16 59.8 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 PSC68689.1 - 8.5e-15 55.1 2.3 1.3e-14 54.5 2.3 1.5 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 PSC68689.1 - 8e-13 48.1 0.1 1.9e-12 46.9 0.1 1.5 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 PSC68689.1 - 7.8e-11 41.9 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 PSC68689.1 - 1.2e-09 38.1 0.6 1.3e-08 34.7 0.4 2.1 1 1 1 2 2 2 1 NmrA-like family KR PF08659.10 PSC68689.1 - 3.5e-06 27.0 1.4 1.8e-05 24.8 1.4 2.0 1 1 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 PSC68689.1 - 0.00057 19.1 0.0 0.00087 18.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 PSC68689.1 - 0.00066 18.9 0.3 0.0014 17.8 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.25 PSC68689.1 - 0.011 15.3 2.1 0.14 11.6 2.1 2.3 1 1 0 1 1 1 0 short chain dehydrogenase PAN_1 PF00024.26 PSC68690.1 - 1.1e-51 172.7 97.0 0.00035 20.5 0.5 17.5 16 1 0 17 17 17 17 PAN domain Peptidase_S8 PF00082.22 PSC68690.1 - 1.2e-34 119.9 9.3 2.3e-34 119.1 9.3 1.4 1 0 0 1 1 1 1 Subtilase family PAN_4 PF14295.6 PSC68690.1 - 5.8e-16 58.1 151.1 6.5e-06 26.0 1.6 18.3 18 0 0 18 18 18 10 PAN domain T2SSppdC PF12528.8 PSC68690.1 - 0.026 15.3 0.0 13 6.7 0.0 3.2 3 0 0 3 3 3 0 Type II secretion prepilin peptidase dependent protein C DnaJ PF00226.31 PSC68691.1 - 2e-13 50.3 0.0 3.8e-13 49.3 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain UCR_UQCRX_QCR9 PF05365.12 PSC68691.1 - 0.027 14.4 0.0 0.066 13.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like GRP PF07172.11 PSC68691.1 - 1.2 9.9 14.0 2.5 8.8 8.4 2.3 2 0 0 2 2 2 0 Glycine rich protein family DJ-1_PfpI PF01965.24 PSC68692.1 - 6.6e-14 52.0 0.0 1.9e-13 50.6 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 PSC68692.1 - 6.7e-08 32.4 0.0 4.3e-07 29.8 0.0 2.0 1 1 0 1 1 1 1 ThiJ/PfpI family-like Copper-bind PF00127.20 PSC68694.1 - 6.7e-35 119.5 0.0 8.5e-35 119.2 0.0 1.1 1 0 0 1 1 1 1 Copper binding proteins, plastocyanin/azurin family Cupredoxin_1 PF13473.6 PSC68694.1 - 2.4e-09 37.2 0.0 5.3e-09 36.1 0.0 1.5 1 1 0 1 1 1 1 Cupredoxin-like domain adh_short_C2 PF13561.6 PSC68695.1 - 6.6e-56 189.5 5.5 9.7e-56 188.9 5.5 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PSC68695.1 - 4.5e-46 156.8 4.2 6.3e-46 156.3 4.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PSC68695.1 - 1.3e-10 41.5 3.4 2.1e-10 40.8 3.4 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PSC68695.1 - 0.0015 18.0 1.1 0.0034 16.9 1.1 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 PSC68695.1 - 0.0026 16.9 0.2 0.0043 16.2 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Peptidase_M91 PF14891.6 PSC68696.1 - 0.084 13.2 0.3 0.098 13.0 0.3 1.1 1 0 0 1 1 1 0 Effector protein L51_S25_CI-B8 PF05047.16 PSC68697.1 - 1.4e-10 40.9 0.0 2.5e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain R3H PF01424.22 PSC68698.1 - 4.2e-10 39.5 0.1 8.4e-10 38.5 0.1 1.5 1 0 0 1 1 1 1 R3H domain SUZ PF12752.7 PSC68698.1 - 4.3e-09 37.0 3.1 8.9e-09 36.0 0.0 3.2 2 1 0 2 2 2 1 SUZ domain PolyA_pol PF01743.20 PSC68699.1 - 1.4e-18 67.5 0.0 3e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 PSC68699.1 - 1.2e-12 47.4 0.0 2.1e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A SR-25 PF10500.9 PSC68699.1 - 0.042 13.4 18.4 0.82 9.2 15.7 2.8 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein RecO_C PF02565.15 PSC68699.1 - 0.054 13.3 0.0 0.23 11.3 0.0 2.1 1 0 0 1 1 1 0 Recombination protein O C terminal DUF4614 PF15391.6 PSC68699.1 - 2.5 8.1 7.8 5.5 7.0 7.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Myb_DNA-bind_7 PF15963.5 PSC68700.1 - 1.1e-25 89.3 0.1 1.1e-25 89.3 0.1 2.8 3 0 0 3 3 3 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 PSC68700.1 - 3.8e-07 30.2 0.0 8.3e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain SARAF PF06682.12 PSC68700.1 - 0.00062 19.5 4.3 0.00062 19.5 4.3 5.3 4 2 0 4 4 4 2 SOCE-associated regulatory factor of calcium homoeostasis Myb_DNA-bind_6 PF13921.6 PSC68700.1 - 0.0033 17.6 0.0 0.0068 16.6 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain V-SNARE_C PF12352.8 PSC68701.1 - 1.3e-06 28.6 11.8 0.00042 20.5 0.0 4.3 5 0 0 5 5 5 2 Snare region anchored in the vesicle membrane C-terminus Swi3 PF07962.12 PSC68701.1 - 0.026 14.5 0.0 11 6.2 0.0 2.5 2 0 0 2 2 2 0 Replication Fork Protection Component Swi3 PhaP_Bmeg PF09602.10 PSC68701.1 - 0.064 13.2 0.6 1.5 8.7 0.1 2.5 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) KORA PF16509.5 PSC68701.1 - 0.066 13.5 3.9 0.066 13.5 0.4 2.7 3 0 0 3 3 3 0 TrfB plasmid transcriptional repressor DUF5089 PF17002.5 PSC68701.1 - 0.16 11.8 10.9 1.1 9.1 0.6 3.3 4 0 0 4 4 4 0 Domain of unknown function (DUF5089) HAUS-augmin3 PF14932.6 PSC68701.1 - 0.49 9.9 6.3 0.15 11.6 0.4 2.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 V-SNARE_C PF12352.8 PSC68702.1 - 7.6e-08 32.5 7.3 0.00041 20.6 0.0 4.0 4 0 0 4 4 4 2 Snare region anchored in the vesicle membrane C-terminus Swi3 PF07962.12 PSC68702.1 - 0.025 14.6 0.0 10 6.2 0.0 2.4 2 0 0 2 2 2 0 Replication Fork Protection Component Swi3 KORA PF16509.5 PSC68702.1 - 0.049 13.9 3.9 0.064 13.5 0.4 2.9 3 0 0 3 3 3 0 TrfB plasmid transcriptional repressor DUF5089 PF17002.5 PSC68702.1 - 0.11 12.3 9.1 1 9.2 0.6 2.9 4 0 0 4 4 4 0 Domain of unknown function (DUF5089) Cyanate_lyase PF02560.14 PSC68704.1 - 7.6e-29 99.4 0.0 1.1e-28 98.8 0.0 1.3 1 0 0 1 1 1 1 Cyanate lyase C-terminal domain Methyltransf_8 PF05148.15 PSC68706.1 - 1.7e-66 224.2 0.0 3e-66 223.4 0.0 1.4 1 0 0 1 1 1 1 Hypothetical methyltransferase HATPase_c_3 PF13589.6 PSC68706.1 - 4.3e-12 46.0 0.0 8.7e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Methyltransf_11 PF08241.12 PSC68706.1 - 1.7e-05 25.4 0.0 9.8e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC68706.1 - 0.0026 18.4 0.1 0.049 14.3 0.1 3.0 1 1 0 1 1 1 1 Methyltransferase domain HATPase_c PF02518.26 PSC68706.1 - 0.003 18.0 0.0 0.0072 16.8 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SMC_hinge PF06470.13 PSC68706.1 - 0.035 14.4 0.0 0.24 11.7 0.0 2.4 1 1 0 1 1 1 0 SMC proteins Flexible Hinge Domain MTS PF05175.14 PSC68706.1 - 0.064 12.8 0.1 0.54 9.8 0.1 2.2 1 1 1 2 2 2 0 Methyltransferase small domain Flagellin_N PF00669.20 PSC68706.1 - 0.24 11.5 2.6 0.82 9.8 2.6 1.9 1 0 0 1 1 1 0 Bacterial flagellin N-terminal helical region MoaE PF02391.17 PSC68707.1 - 8.1e-39 132.4 0.2 2e-38 131.1 0.2 1.8 1 0 0 1 1 1 1 MoaE protein Aida_C2 PF14186.6 PSC68707.1 - 5.7e-36 123.3 0.0 1e-35 122.5 0.0 1.4 1 0 0 1 1 1 1 Cytoskeletal adhesion EF-hand_4 PF12763.7 PSC68707.1 - 0.11 12.5 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Cytoskeletal-regulatory complex EF hand TetR_C_35 PF18556.1 PSC68708.1 - 0.032 14.4 1.7 0.96 9.6 0.7 2.2 2 0 0 2 2 2 0 Bacterial Tetracyclin repressor, C-terminal domain ShK PF01549.24 PSC68709.1 - 6.7e-06 26.5 9.3 1.7e-05 25.2 9.3 1.8 1 0 0 1 1 1 1 ShK domain-like Raptor_N PF14538.6 PSC68711.1 - 9.6e-67 223.5 0.0 1.5e-66 222.9 0.0 1.3 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 PSC68711.1 - 3.2e-11 43.6 0.0 0.026 15.4 0.0 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat HEAT PF02985.22 PSC68711.1 - 3e-05 23.9 8.1 0.0084 16.3 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat ANAPC4_WD40 PF12894.7 PSC68711.1 - 0.0098 16.2 0.0 3.5 8.0 0.0 3.4 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain HEAT_2 PF13646.6 PSC68711.1 - 0.31 11.5 14.4 4.5 7.7 0.0 5.1 5 0 0 5 5 5 0 HEAT repeats HEAT_EZ PF13513.6 PSC68711.1 - 5.1 7.7 12.6 11 6.6 0.2 5.0 4 0 0 4 4 4 0 HEAT-like repeat SMC_N PF02463.19 PSC68712.1 - 3.3e-57 193.5 0.0 5e-57 192.9 0.0 1.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 PSC68712.1 - 3.1e-20 72.6 0.5 1e-19 71.0 0.0 2.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 PSC68712.1 - 1.7e-17 64.6 5.0 1.7e-17 64.6 5.0 6.0 3 2 2 5 5 3 1 AAA domain AAA_21 PF13304.6 PSC68712.1 - 9.5e-14 51.9 3.0 1.8e-07 31.3 0.0 3.4 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PSC68712.1 - 1.1e-06 28.6 5.6 1.1e-06 28.6 5.6 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 PSC68712.1 - 4e-06 26.5 0.0 8.1e-06 25.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 PSC68712.1 - 0.012 15.8 0.8 0.045 14.0 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit UPA_2 PF17809.1 PSC68712.1 - 0.13 12.1 4.5 8.9 6.2 0.0 4.2 3 1 1 4 4 4 0 UPA domain DUF2322 PF10084.9 PSC68712.1 - 0.28 11.3 4.5 2.2 8.4 0.1 3.5 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) ABC_tran PF00005.27 PSC68712.1 - 0.37 11.3 0.0 0.37 11.3 0.0 7.0 4 3 1 5 5 4 0 ABC transporter FlaC_arch PF05377.11 PSC68712.1 - 2.2 8.7 12.4 3 8.3 0.5 5.4 5 1 1 6 6 5 0 Flagella accessory protein C (FlaC) Retrotran_gag_2 PF14223.6 PSC68713.1 - 1.4e-25 89.6 0.0 1.8e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 PSC68713.1 - 0.16 11.7 0.0 0.25 11.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) Abhydrolase_2 PF02230.16 PSC68715.1 - 1.8e-45 155.4 0.0 2e-45 155.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 PSC68715.1 - 3.1e-09 36.6 0.5 7.2e-07 28.9 0.0 2.1 1 1 1 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 PSC68715.1 - 6.3e-09 35.7 0.0 8.1e-09 35.3 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 PSC68715.1 - 9.1e-08 32.0 0.0 1.3e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 PSC68715.1 - 4.3e-07 29.4 0.3 0.00059 19.2 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 PSC68715.1 - 8.5e-05 22.5 0.2 0.15 11.9 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 PSC68715.1 - 0.0024 17.7 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.11 PSC68715.1 - 0.0098 15.8 0.4 2.3 8.1 0.0 2.1 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.25 PSC68715.1 - 0.019 14.9 0.0 0.04 13.8 0.0 1.5 2 0 0 2 2 2 0 Lipase (class 3) Abhydrolase_6 PF12697.7 PSC68715.1 - 0.056 14.0 0.1 0.073 13.7 0.1 1.3 1 1 0 1 1 1 0 Alpha/beta hydrolase family AXE1 PF05448.12 PSC68715.1 - 0.13 10.9 0.5 3.5 6.2 0.1 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) Phage_min_tail PF05939.13 PSC68715.1 - 0.14 12.6 0.0 0.21 12.0 0.0 1.2 1 0 0 1 1 1 0 Phage minor tail protein Abhydrolase_2 PF02230.16 PSC68716.1 - 7.3e-56 189.4 0.0 8.6e-56 189.1 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 PSC68716.1 - 4.6e-09 36.1 0.4 1e-06 28.4 0.0 2.3 1 1 1 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 PSC68716.1 - 9.7e-09 35.1 0.0 1.4e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 PSC68716.1 - 1.1e-08 35.0 0.0 5.9e-08 32.6 0.0 1.9 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 PSC68716.1 - 1.3e-07 31.1 0.4 0.00083 18.7 0.0 2.9 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PSC68716.1 - 7.4e-05 23.4 0.7 0.00021 22.0 0.7 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 PSC68716.1 - 0.00016 21.6 0.2 0.22 11.3 0.1 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_5 PF12695.7 PSC68716.1 - 0.0033 17.2 0.0 0.0053 16.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PSC68716.1 - 0.015 15.0 1.7 8.5 5.9 0.4 3.0 2 1 1 3 3 3 0 alpha/beta hydrolase fold BAAT_C PF08840.11 PSC68716.1 - 0.017 15.0 0.3 3.3 7.6 0.0 2.1 1 1 1 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.25 PSC68716.1 - 0.027 14.3 0.0 0.056 13.3 0.0 1.4 2 0 0 2 2 2 0 Lipase (class 3) Phage_min_tail PF05939.13 PSC68716.1 - 0.2 12.1 0.0 0.31 11.4 0.0 1.2 1 0 0 1 1 1 0 Phage minor tail protein AXE1 PF05448.12 PSC68716.1 - 0.22 10.1 0.5 4.6 5.8 0.1 2.1 2 0 0 2 2 2 0 Acetyl xylan esterase (AXE1) LpqV PF17301.2 PSC68717.1 - 0.077 13.2 0.0 0.12 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative lipoprotein LpqV VPR PF00522.18 PSC68717.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.6 1 1 0 1 1 1 0 VPR/VPX protein DUF2722 PF10846.8 PSC68718.1 - 0.0049 15.9 8.6 0.0085 15.1 8.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) bZIP_1 PF00170.21 PSC68718.1 - 0.011 15.9 8.5 0.012 15.7 6.5 2.1 1 1 0 1 1 1 0 bZIP transcription factor Roughex PF06020.11 PSC68718.1 - 0.039 13.1 9.0 0.068 12.3 9.0 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 PSC68718.1 - 0.052 13.2 17.0 0.038 13.6 14.5 1.9 2 0 0 2 2 2 0 Spt20 family Velvet PF11754.8 PSC68718.1 - 0.15 12.0 6.0 0.31 10.9 6.0 1.6 1 0 0 1 1 1 0 Velvet factor CDK2AP PF09806.9 PSC68718.1 - 1.2 9.2 22.3 0.83 9.7 3.2 3.0 3 0 0 3 3 3 0 Cyclin-dependent kinase 2-associated protein DUF572 PF04502.13 PSC68718.1 - 1.6 8.3 8.0 2.6 7.6 8.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF572) Neur_chan_memb PF02932.16 PSC68718.1 - 2.1 8.4 7.6 10 6.1 6.2 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region V_ATPase_I PF01496.19 PSC68718.1 - 4.3 5.1 9.0 6.5 4.5 9.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ctr PF04145.15 PSC68719.1 - 3.6e-19 69.9 0.2 1.2e-18 68.2 0.0 1.9 2 0 0 2 2 2 1 Ctr copper transporter family rve PF00665.26 PSC68719.1 - 1.9e-18 66.7 0.0 4.5e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC68719.1 - 0.0061 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Ctr PF04145.15 PSC68720.1 - 3.6e-19 69.8 0.2 1.2e-18 68.2 0.0 1.9 2 0 0 2 2 2 1 Ctr copper transporter family rve PF00665.26 PSC68720.1 - 1.9e-18 66.8 0.0 4.5e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC68720.1 - 0.0061 16.3 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Acetyltransf_1 PF00583.25 PSC68721.1 - 2.9e-07 30.7 0.0 4.3e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PSC68721.1 - 0.00045 20.2 0.0 0.00066 19.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PSC68721.1 - 0.0057 17.1 0.0 0.0091 16.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 PSC68721.1 - 0.014 15.5 0.0 0.022 14.9 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sec1 PF00995.23 PSC68723.1 - 6.6e-103 345.9 0.0 8e-103 345.6 0.0 1.0 1 0 0 1 1 1 1 Sec1 family Lipase_GDSL_2 PF13472.6 PSC68724.1 - 5.7e-05 23.6 0.0 8.5e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family UCH PF00443.29 PSC68725.1 - 1.1e-33 116.8 0.0 2.2e-33 115.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PSC68725.1 - 2.2e-14 53.8 0.0 4e-13 49.7 0.0 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 PSC68725.1 - 0.0003 20.5 0.0 0.00058 19.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUSP PF06337.12 PSC68725.1 - 0.00089 19.8 0.0 3 8.5 0.0 4.2 4 1 0 4 4 4 1 DUSP domain UIM PF02809.20 PSC68725.1 - 0.4 10.7 5.8 1.7 8.7 5.8 2.2 1 0 0 1 1 1 0 Ubiquitin interaction motif zinc-ribbons_6 PF07191.12 PSC68725.1 - 0.57 10.2 3.8 13 5.9 0.9 2.9 2 1 0 2 2 2 0 zinc-ribbons Aquarius_N PF16399.5 PSC68726.1 - 1.6e-277 922.8 0.0 2.2e-277 922.4 0.0 1.1 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_11 PF13086.6 PSC68726.1 - 2.8e-26 92.9 0.0 1.1e-25 90.9 0.0 2.0 2 1 0 2 2 2 1 AAA domain AAA_12 PF13087.6 PSC68726.1 - 2.5e-25 89.3 0.0 3.9e-25 88.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain SAP PF02037.27 PSC68726.1 - 1.5e-09 37.4 0.2 3.5e-09 36.2 0.2 1.7 1 0 0 1 1 1 1 SAP domain AAA_19 PF13245.6 PSC68726.1 - 4.6e-09 36.8 0.0 1.8e-08 34.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 PSC68726.1 - 0.00049 19.9 0.1 0.0014 18.4 0.1 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain ResIII PF04851.15 PSC68726.1 - 0.0057 16.7 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UvrD-helicase PF00580.21 PSC68726.1 - 0.0063 16.1 0.0 0.0063 16.1 0.0 1.7 2 0 0 2 2 1 1 UvrD/REP helicase N-terminal domain AAA PF00004.29 PSC68726.1 - 0.023 15.1 0.0 0.064 13.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DEAD PF00270.29 PSC68726.1 - 0.031 14.0 0.0 0.062 13.1 0.0 1.5 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 PSC68726.1 - 0.053 13.8 0.1 0.31 11.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 PSC68726.1 - 0.069 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_5 PF07728.14 PSC68726.1 - 0.072 13.1 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PSC68726.1 - 0.093 13.1 9.5 0.27 11.6 0.0 3.9 3 0 0 3 3 3 0 AAA ATPase domain AAA_33 PF13671.6 PSC68726.1 - 0.1 12.8 0.0 2.3 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 PSC68726.1 - 0.12 12.1 0.3 5 6.8 0.0 3.0 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase FAD_binding_3 PF01494.19 PSC68727.1 - 3e-09 36.6 4.5 2.3e-08 33.7 1.9 2.8 2 1 0 2 2 2 1 FAD binding domain FAD_binding_3 PF01494.19 PSC68728.1 - 5.3e-09 35.8 5.2 3.9e-08 32.9 2.4 2.8 2 1 0 2 2 2 1 FAD binding domain AIRS_C PF02769.22 PSC68728.1 - 0.34 11.0 2.5 10 6.3 0.0 3.0 3 0 0 3 3 3 0 AIR synthase related protein, C-terminal domain UPF0029 PF01205.19 PSC68729.1 - 1.2e-26 93.1 0.0 2.4e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 U-box PF04564.15 PSC68729.1 - 4.5e-12 46.0 0.0 7.5e-12 45.3 0.0 1.4 1 0 0 1 1 1 1 U-box domain DUF1949 PF09186.11 PSC68729.1 - 4.2e-08 32.9 0.0 9.6e-08 31.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1949) zf-Nse PF11789.8 PSC68729.1 - 4e-06 26.6 0.0 8.3e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 PSC68729.1 - 0.0079 16.3 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 PSC68729.1 - 0.083 12.9 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger hnRNP_Q_AcD PF18360.1 PSC68730.1 - 4.8e-28 96.9 0.2 1.4e-14 53.8 0.0 2.1 2 0 0 2 2 2 2 Heterogeneous nuclear ribonucleoprotein Q acidic domain DUF3486 PF11985.8 PSC68730.1 - 0.0004 20.9 0.2 0.0012 19.3 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3486) hnRNP_Q_AcD PF18360.1 PSC68731.1 - 4.6e-28 97.0 0.2 1.4e-14 53.8 0.0 2.1 2 0 0 2 2 2 2 Heterogeneous nuclear ribonucleoprotein Q acidic domain DUF3486 PF11985.8 PSC68731.1 - 0.00039 20.9 0.2 0.0012 19.3 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3486) DUF1990 PF09348.10 PSC68732.1 - 2.1e-29 102.6 0.0 2.6e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1990) SBP PF03110.14 PSC68733.1 - 6e-26 90.6 9.6 1.4e-25 89.4 9.6 1.7 1 0 0 1 1 1 1 SBP domain Ank_3 PF13606.6 PSC68733.1 - 0.024 15.1 0.1 3.4 8.5 0.0 3.5 3 0 0 3 3 3 0 Ankyrin repeat Ank_2 PF12796.7 PSC68733.1 - 0.13 12.8 0.0 1.1 9.9 0.0 2.4 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) PIG-L PF02585.17 PSC68734.1 - 7.8e-19 68.6 0.0 1.2e-18 68.1 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase TP6A_N PF04406.14 PSC68735.1 - 3.4e-21 75.0 0.1 7.4e-21 73.9 0.1 1.6 1 0 0 1 1 1 1 Type IIB DNA topoisomerase A_thal_3526 PF09713.10 PSC68735.1 - 1.8e-17 63.3 0.0 4.3e-17 62.1 0.0 1.7 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) Ham1p_like PF01725.16 PSC68735.1 - 0.11 12.4 0.6 0.23 11.4 0.6 1.5 1 0 0 1 1 1 0 Ham1 family TRM13 PF05206.14 PSC68736.1 - 8.9e-61 205.7 0.0 2.5e-60 204.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 PSC68736.1 - 5.1e-08 32.5 7.0 5.1e-08 32.5 7.0 1.9 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein Methyltransf_32 PF13679.6 PSC68736.1 - 0.00043 20.3 0.4 0.00043 20.3 0.4 2.6 2 1 0 2 2 2 1 Methyltransferase domain zf-U11-48K PF05253.12 PSC68736.1 - 0.083 12.8 3.9 0.41 10.6 3.9 2.3 1 1 0 1 1 1 0 U11-48K-like CHHC zinc finger vATP-synt_AC39 PF01992.16 PSC68737.1 - 7e-108 361.1 0.1 7.8e-108 360.9 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit CbiX PF01903.17 PSC68737.1 - 0.17 12.3 0.4 0.99 9.8 0.1 2.1 2 0 0 2 2 2 0 CbiX Ephrin_rec_like PF07699.13 PSC68738.1 - 1e-10 41.2 63.1 1e-05 25.2 7.2 8.7 3 2 6 9 9 9 8 Putative ephrin-receptor like Ephrin_rec_like PF07699.13 PSC68739.1 - 1e-10 41.2 63.1 1e-05 25.2 7.2 8.7 3 2 6 9 9 9 8 Putative ephrin-receptor like Ephrin_rec_like PF07699.13 PSC68740.1 - 1e-10 41.2 63.1 1e-05 25.2 7.2 8.7 3 2 6 9 9 9 8 Putative ephrin-receptor like PEPCK_ATP PF01293.20 PSC68741.1 - 1e-107 360.7 0.0 1.4e-107 360.3 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_24 PF13479.6 PSC68741.1 - 0.029 14.1 0.0 0.19 11.4 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 PSC68741.1 - 0.12 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain UPRTase PF14681.6 PSC68742.1 - 3.3e-55 186.7 0.0 3.7e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 PSC68742.1 - 5.7e-05 22.7 0.1 8.5e-05 22.1 0.1 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain FAD-oxidase_C PF02913.19 PSC68743.1 - 5.4e-57 193.3 1.0 1.3e-56 192.1 0.1 2.2 2 1 0 2 2 2 1 FAD linked oxidases, C-terminal domain Amino_oxidase PF01593.24 PSC68743.1 - 2.1e-52 178.9 0.3 3.1e-52 178.4 0.3 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_4 PF01565.23 PSC68743.1 - 9.6e-35 119.3 1.4 3.9e-34 117.4 1.4 2.2 1 0 0 1 1 1 1 FAD binding domain ABC_tran PF00005.27 PSC68743.1 - 3.1e-24 86.0 0.0 7.2e-24 84.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter NAD_binding_8 PF13450.6 PSC68743.1 - 2.7e-10 40.3 0.9 1.2e-09 38.2 0.1 2.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PSC68743.1 - 8.7e-10 38.7 6.7 4e-08 33.2 6.7 3.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 PSC68743.1 - 2.1e-08 33.9 0.1 3.9e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PSC68743.1 - 1.6e-05 24.3 0.6 3.1e-05 23.3 0.6 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PSC68743.1 - 7e-05 22.2 0.2 0.00015 21.1 0.2 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 PSC68743.1 - 0.00023 20.6 0.7 0.00044 19.6 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 PSC68743.1 - 0.0017 17.1 0.2 0.003 16.3 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein zf-MYND PF01753.18 PSC68743.1 - 0.0019 18.2 2.9 0.0048 17.0 2.9 1.6 1 0 0 1 1 1 1 MYND finger AlaDh_PNT_C PF01262.21 PSC68743.1 - 0.011 15.0 0.6 0.024 13.9 0.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 PSC68743.1 - 0.013 14.6 0.9 0.026 13.6 0.9 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A AAA_29 PF13555.6 PSC68743.1 - 0.043 13.6 0.1 0.17 11.7 0.1 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 PSC68743.1 - 0.06 13.2 0.5 6.8 6.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Lycopene_cycl PF05834.12 PSC68743.1 - 0.07 12.2 0.2 0.15 11.1 0.2 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein AAA_16 PF13191.6 PSC68743.1 - 0.19 12.1 6.5 0.98 9.8 0.1 3.5 3 0 0 3 3 3 0 AAA ATPase domain Pyr_redox PF00070.27 PSC68743.1 - 0.24 12.0 1.6 0.8 10.3 0.3 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD-oxidase_C PF02913.19 PSC68744.1 - 4.9e-57 193.4 1.0 1.3e-56 192.1 0.1 2.3 2 1 0 2 2 2 1 FAD linked oxidases, C-terminal domain Amino_oxidase PF01593.24 PSC68744.1 - 2.1e-52 178.9 0.3 3e-52 178.4 0.3 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase FAD_binding_4 PF01565.23 PSC68744.1 - 9.4e-35 119.4 1.4 3.9e-34 117.4 1.4 2.2 1 0 0 1 1 1 1 FAD binding domain ABC_tran PF00005.27 PSC68744.1 - 3.1e-24 86.1 0.0 7.1e-24 84.9 0.0 1.7 1 0 0 1 1 1 1 ABC transporter NAD_binding_8 PF13450.6 PSC68744.1 - 2.6e-10 40.4 0.9 1.2e-09 38.3 0.1 2.8 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PSC68744.1 - 9.4e-10 38.6 6.7 4e-08 33.2 6.7 3.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 PSC68744.1 - 2.1e-08 34.0 0.1 3.9e-08 33.1 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PSC68744.1 - 1.6e-05 24.3 0.6 3.1e-05 23.4 0.6 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PSC68744.1 - 6.8e-05 22.2 0.2 0.00015 21.1 0.2 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.19 PSC68744.1 - 0.00022 20.6 0.7 0.00043 19.6 0.7 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 PSC68744.1 - 0.0017 17.1 0.2 0.003 16.3 0.2 1.4 1 0 0 1 1 1 1 HI0933-like protein zf-MYND PF01753.18 PSC68744.1 - 0.002 18.2 2.9 0.0047 17.0 2.9 1.6 1 0 0 1 1 1 1 MYND finger AlaDh_PNT_C PF01262.21 PSC68744.1 - 0.011 15.0 0.6 0.024 13.9 0.6 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 PSC68744.1 - 0.013 14.7 0.9 0.026 13.6 0.9 1.5 1 0 0 1 1 1 0 Glucose inhibited division protein A AAA_29 PF13555.6 PSC68744.1 - 0.042 13.6 0.1 0.17 11.7 0.1 2.0 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 PSC68744.1 - 0.058 13.2 0.5 6.7 6.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Lycopene_cycl PF05834.12 PSC68744.1 - 0.069 12.2 0.2 0.15 11.1 0.2 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein AAA_16 PF13191.6 PSC68744.1 - 0.18 12.2 6.5 0.97 9.8 0.1 3.5 3 0 0 3 3 3 0 AAA ATPase domain Pyr_redox PF00070.27 PSC68744.1 - 0.24 12.0 1.6 0.8 10.3 0.3 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SpoU_methylase PF00588.19 PSC68745.1 - 8.3e-25 87.6 0.1 3.6e-24 85.6 0.0 2.1 2 0 0 2 2 2 1 SpoU rRNA Methylase family EloA-BP1 PF15870.5 PSC68745.1 - 0.0057 16.9 0.2 0.013 15.8 0.2 1.5 1 0 0 1 1 1 1 ElonginA binding-protein 1 EloA-BP1 PF15870.5 PSC68746.1 - 1.5e-05 25.3 0.1 5.2e-05 23.6 0.0 1.8 2 0 0 2 2 2 1 ElonginA binding-protein 1 Ycf34 PF10718.9 PSC68746.1 - 0.042 14.6 0.1 0.12 13.1 0.1 1.7 1 0 0 1 1 1 0 Hypothetical chloroplast protein Ycf34 Jun PF03957.13 PSC68746.1 - 0.35 10.7 10.9 0.033 14.1 6.6 1.5 2 0 0 2 2 2 0 Jun-like transcription factor Pex14_N PF04695.13 PSC68746.1 - 0.38 11.4 7.3 0.62 10.7 4.2 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.25 PSC68747.1 - 1.7e-47 162.0 0.0 2.2e-47 161.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC68747.1 - 7.3e-16 58.2 0.0 1e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FTA2 PF13095.6 PSC68747.1 - 0.034 13.8 0.0 2.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 PSC68747.1 - 0.042 13.2 0.0 0.072 12.4 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Torus PF16131.5 PSC68748.1 - 7.1e-27 94.3 0.5 7.1e-27 94.3 0.5 2.2 2 0 0 2 2 2 1 Torus domain RRM_1 PF00076.22 PSC68748.1 - 0.00023 20.9 0.0 0.00055 19.7 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 PSC68748.1 - 0.00058 19.8 4.3 0.0011 19.0 4.3 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 PSC68748.1 - 0.0052 16.7 6.8 0.011 15.6 6.8 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) IU_nuc_hydro PF01156.19 PSC68749.1 - 9.5e-86 288.1 0.1 1.1e-85 287.9 0.1 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Mlh1_C PF16413.5 PSC68750.1 - 1.4e-64 218.1 0.0 2.2e-64 217.5 0.0 1.2 1 0 0 1 1 1 1 DNA mismatch repair protein Mlh1 C-terminus NAD_binding_10 PF13460.6 PSC68750.1 - 1.9e-31 109.4 0.3 4.1e-31 108.3 0.3 1.5 1 0 0 1 1 1 1 NAD(P)H-binding DNA_mis_repair PF01119.19 PSC68750.1 - 5.9e-17 61.5 0.0 6.7e-09 35.4 0.1 2.6 2 0 0 2 2 2 2 DNA mismatch repair protein, C-terminal domain Epimerase PF01370.21 PSC68750.1 - 3.9e-05 23.2 0.0 9.2e-05 22.0 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family AlaDh_PNT_C PF01262.21 PSC68750.1 - 0.0033 16.7 0.4 0.0063 15.8 0.4 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 3Beta_HSD PF01073.19 PSC68750.1 - 0.008 15.2 0.2 0.013 14.5 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 PSC68750.1 - 0.0096 15.5 0.1 0.019 14.5 0.1 1.4 1 0 0 1 1 1 1 NmrA-like family NAD_binding_7 PF13241.6 PSC68750.1 - 0.045 14.2 0.1 0.14 12.6 0.1 1.9 1 0 0 1 1 1 0 Putative NAD(P)-binding adh_short_C2 PF13561.6 PSC68750.1 - 0.056 13.0 0.4 0.13 11.8 0.4 1.7 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Ank_2 PF12796.7 PSC68751.1 - 1.3e-60 201.9 41.7 5.4e-10 39.7 0.2 7.7 3 2 7 10 10 10 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC68751.1 - 2.8e-54 180.8 12.8 7.9e-08 32.7 0.3 11.1 4 3 7 11 11 11 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC68751.1 - 1.8e-38 126.1 15.7 0.015 15.8 0.1 12.8 14 0 0 14 14 14 10 Ankyrin repeat Ank PF00023.30 PSC68751.1 - 3.1e-38 128.6 47.0 7.1e-05 23.1 1.0 13.0 13 0 0 13 13 13 11 Ankyrin repeat Ank_5 PF13857.6 PSC68751.1 - 3.2e-29 100.6 29.0 5.5e-06 26.6 0.2 11.1 9 2 3 12 12 12 10 Ankyrin repeats (many copies) DUF5010 PF16402.5 PSC68751.1 - 0.0013 17.6 0.4 1.2 7.9 0.0 3.3 4 0 0 4 4 4 2 Domain of unknown function (DUF5010) DNA_pol3_gamma3 PF12169.8 PSC68751.1 - 0.012 15.5 19.3 10 6.0 0.1 7.7 6 2 3 9 9 9 0 DNA polymerase III subunits gamma and tau domain III DKCLD PF08068.12 PSC68752.1 - 6e-33 112.7 0.8 1.1e-30 105.4 0.3 2.6 3 0 0 3 3 3 1 DKCLD (NUC011) domain TruB_N PF01509.18 PSC68752.1 - 1.1e-22 81.1 0.6 1.2e-19 71.2 0.6 3.5 1 1 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 PSC68752.1 - 1.5e-22 79.5 0.7 3.1e-22 78.5 0.7 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain PUA PF01472.20 PSC68752.1 - 4.7e-21 74.5 1.1 1.1e-20 73.4 1.1 1.7 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 PSC68752.1 - 0.0081 16.4 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain DUF3682 PF12446.8 PSC68752.1 - 0.27 11.7 14.0 0.46 11.0 14.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) RNA_polI_A34 PF08208.11 PSC68752.1 - 0.34 11.0 23.5 0.61 10.1 23.5 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Coilin_N PF15862.5 PSC68752.1 - 2.5 7.9 15.7 4.4 7.1 15.7 1.3 1 0 0 1 1 1 0 Coilin N-terminus RR_TM4-6 PF06459.12 PSC68752.1 - 4.2 7.1 13.0 5.6 6.7 13.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Med19 PF10278.9 PSC68752.1 - 4.4 7.2 15.8 6.8 6.6 15.8 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 Nuc_sug_transp PF04142.15 PSC68753.1 - 2.3e-73 247.1 13.1 1e-62 212.1 6.7 2.1 2 0 0 2 2 2 2 Nucleotide-sugar transporter EamA PF00892.20 PSC68753.1 - 0.0015 18.7 2.1 0.0015 18.7 2.1 3.8 4 1 0 4 4 4 1 EamA-like transporter family UAA PF08449.11 PSC68753.1 - 0.0081 15.4 7.5 0.021 14.0 7.5 1.7 1 1 0 1 1 1 1 UAA transporter family Phage_Coat_Gp8 PF05371.12 PSC68753.1 - 0.084 12.7 0.9 0.39 10.5 0.9 2.2 1 0 0 1 1 1 0 Phage major coat protein, Gp8 Phage_holin_2_1 PF04971.12 PSC68753.1 - 0.11 12.5 4.2 6.9 6.8 0.2 2.8 2 0 0 2 2 2 0 Bacteriophage P21 holin S TPT PF03151.16 PSC68753.1 - 1.4 8.2 9.2 0.19 11.0 1.6 2.3 1 1 1 2 2 2 0 Triose-phosphate Transporter family Oxysterol_BP PF01237.18 PSC68755.1 - 1.3e-113 379.7 0.0 2.9e-113 378.5 0.0 1.6 1 1 0 1 1 1 1 Oxysterol-binding protein PH PF00169.29 PSC68755.1 - 1.5e-06 28.7 0.0 7.9e-06 26.3 0.0 2.1 1 1 0 1 1 1 1 PH domain PH_11 PF15413.6 PSC68755.1 - 7.2e-06 26.4 0.0 4e-05 24.0 0.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 PSC68755.1 - 0.0013 19.0 0.2 0.15 12.4 0.1 2.4 2 0 0 2 2 2 1 Pleckstrin homology domain PHA_synth_III_E PF09712.10 PSC68755.1 - 0.046 12.8 0.2 0.078 12.1 0.2 1.2 1 0 0 1 1 1 0 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) FAM194 PF14977.6 PSC68755.1 - 0.098 12.0 0.1 0.16 11.2 0.1 1.3 1 0 0 1 1 1 0 FAM194 protein DUF1524 PF07510.11 PSC68756.1 - 2.3e-14 53.4 0.0 2.3e-14 53.4 0.0 2.1 2 1 0 2 2 1 1 Protein of unknown function (DUF1524) TFIIA PF03153.13 PSC68756.1 - 0.0019 18.3 23.9 0.0028 17.7 23.9 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 PSC68756.1 - 0.017 15.3 6.8 0.027 14.6 6.8 1.4 1 0 0 1 1 1 0 DDHD domain Isy1 PF06246.12 PSC68756.1 - 0.092 12.3 17.0 0.18 11.3 17.0 1.4 1 0 0 1 1 1 0 Isy1-like splicing family MMR1 PF08505.10 PSC68756.1 - 0.15 12.4 13.8 0.24 11.7 13.8 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Pex14_N PF04695.13 PSC68756.1 - 0.19 12.4 12.5 0.43 11.2 12.5 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Macoilin PF09726.9 PSC68756.1 - 0.37 9.3 22.4 0.47 8.9 22.4 1.1 1 0 0 1 1 1 0 Macoilin family EPL1 PF10513.9 PSC68756.1 - 0.52 10.7 9.6 1.1 9.6 9.6 1.5 1 0 0 1 1 1 0 Enhancer of polycomb-like Ndc1_Nup PF09531.10 PSC68756.1 - 1.1 7.9 7.2 1.5 7.4 7.2 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Hid1 PF12722.7 PSC68756.1 - 1.3 7.0 13.8 1.7 6.7 13.8 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Herpes_UL32 PF06070.11 PSC68756.1 - 2.2 5.9 9.9 3.1 5.4 9.9 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 PAT1 PF09770.9 PSC68756.1 - 2.2 6.4 22.4 2.9 6.0 22.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 V_ATPase_I PF01496.19 PSC68756.1 - 2.7 5.8 15.2 3.7 5.3 15.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2828 PF11443.8 PSC68756.1 - 2.9 5.9 11.5 4 5.4 11.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) EOS1 PF12326.8 PSC68756.1 - 2.9 7.8 4.9 5 7.0 4.9 1.4 1 0 0 1 1 1 0 N-glycosylation protein RR_TM4-6 PF06459.12 PSC68756.1 - 3.5 7.4 17.7 5.5 6.7 17.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Membralin PF09746.9 PSC68756.1 - 3.5 6.6 4.2 5 6.1 4.2 1.2 1 0 0 1 1 1 0 Tumour-associated protein NPR3 PF03666.13 PSC68756.1 - 3.6 6.3 11.9 5.5 5.7 11.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 eIF3_subunit PF08597.10 PSC68756.1 - 3.7 7.4 18.9 7.4 6.4 18.9 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit SOBP PF15279.6 PSC68756.1 - 4.5 7.8 10.3 7.7 7.0 10.3 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein eIF-3_zeta PF05091.12 PSC68756.1 - 5 6.0 15.8 7.3 5.4 15.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 PSC68756.1 - 6 5.5 17.9 8.3 5.1 17.9 1.2 1 0 0 1 1 1 0 Presenilin MDM10 PF12519.8 PSC68756.1 - 7 5.4 9.8 11 4.8 9.8 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 CDC45 PF02724.14 PSC68756.1 - 7.1 4.8 20.9 10 4.2 20.9 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF4746 PF15928.5 PSC68756.1 - 8.6 5.7 17.1 14 5.0 17.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Plasmodium_Vir PF05795.11 PSC68756.1 - 9.6 5.5 9.6 14 5.0 9.6 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Acyltransferase PF01553.21 PSC68757.1 - 2.6e-28 98.3 0.0 4.1e-28 97.7 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase UPF0016 PF01169.19 PSC68757.1 - 8.3e-21 74.1 21.5 6.3e-15 55.3 7.4 2.8 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 LysE PF01810.18 PSC68757.1 - 0.00032 20.2 2.9 0.0021 17.6 2.9 2.3 1 1 0 1 1 1 1 LysE type translocator Mntp PF02659.15 PSC68757.1 - 0.0032 17.2 2.4 0.036 13.8 1.2 2.9 2 1 0 2 2 2 1 Putative manganese efflux pump Got1 PF04178.12 PSC68759.1 - 1.1e-12 48.3 13.2 1.3e-12 48.1 13.2 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family FAT PF02259.23 PSC68760.1 - 7.6e-26 91.1 13.1 1.5e-25 90.2 13.1 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 PSC68760.1 - 7.4e-12 45.6 0.0 1.6e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 PSC68760.1 - 0.00011 22.0 0.3 0.00011 22.0 0.3 2.3 2 0 0 2 2 2 1 FATC domain TPR_14 PF13428.6 PSC68760.1 - 0.0043 17.8 0.0 0.086 13.7 0.0 3.5 1 0 0 1 1 1 1 Tetratricopeptide repeat Mito_carr PF00153.27 PSC68761.1 - 1.4e-63 210.9 0.2 5.9e-21 74.2 0.1 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein SLATT_1 PF18181.1 PSC68761.1 - 0.71 9.8 3.2 30 4.6 0.0 2.5 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 Methyltransf_PK PF05891.12 PSC68762.1 - 2.4e-74 249.6 0.0 2.7e-74 249.4 0.0 1.0 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 PSC68762.1 - 1.9e-12 47.7 0.0 1e-11 45.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC68762.1 - 4.2e-10 39.7 0.0 6.6e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC68762.1 - 8.9e-10 39.1 0.0 1.5e-09 38.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC68762.1 - 1.1e-08 35.7 0.0 2e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC68762.1 - 0.00014 21.6 0.0 0.0003 20.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 PSC68762.1 - 0.0045 16.3 0.0 0.0084 15.4 0.0 1.4 1 1 0 1 1 1 1 O-methyltransferase domain Bin3 PF06859.12 PSC68762.1 - 0.0063 17.1 0.0 0.013 16.1 0.0 1.6 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) PMT2_N PF17987.1 PSC68762.1 - 0.092 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Phosphoethanolamine N-methyltransferase 2 N-terminal CheR PF01739.18 PSC68762.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain HATPase_c_3 PF13589.6 PSC68763.1 - 2.4e-08 33.9 1.8 8.7e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PSC68763.1 - 5.3e-05 23.7 0.4 0.00017 22.1 0.0 2.0 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Presenilin PF01080.17 PSC68763.1 - 0.22 10.2 1.8 0.24 10.1 1.8 1.1 1 0 0 1 1 1 0 Presenilin Rrn6 PF10214.9 PSC68763.1 - 0.43 9.0 7.5 0.5 8.8 7.5 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF3824 PF12868.7 PSC68763.1 - 0.51 11.0 5.8 0.63 10.7 4.7 1.7 1 1 1 2 2 2 0 Domain of unknwon function (DUF3824) Spt20 PF12090.8 PSC68763.1 - 0.7 9.5 10.1 0.94 9.0 10.1 1.2 1 0 0 1 1 1 0 Spt20 family AIM3 PF17096.5 PSC68763.1 - 1.7 9.7 10.3 0.2 12.6 5.7 1.8 2 0 0 2 2 2 0 Altered inheritance of mitochondria protein 3 NARP1 PF12569.8 PSC68763.1 - 3.9 6.3 12.6 5.3 5.8 12.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 AP3D1 PF06375.11 PSC68763.1 - 5.6 7.2 17.8 10 6.4 17.8 1.4 1 1 0 1 1 1 0 AP-3 complex subunit delta-1 DUF1524 PF07510.11 PSC68764.1 - 2.4e-19 69.6 0.0 5.9e-19 68.3 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1524) DUF3754 PF12576.8 PSC68764.1 - 0.022 14.7 0.0 0.11 12.5 0.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3754) Nuc_sug_transp PF04142.15 PSC68766.1 - 5.1e-31 108.0 5.5 8.3e-30 104.0 5.5 1.9 1 1 0 1 1 1 1 Nucleotide-sugar transporter UAA PF08449.11 PSC68766.1 - 9.6e-05 21.7 0.2 0.00014 21.2 0.2 1.2 1 0 0 1 1 1 1 UAA transporter family Phage_holin_2_1 PF04971.12 PSC68766.1 - 0.01 15.8 4.6 1.5 8.8 0.3 2.6 2 0 0 2 2 2 0 Bacteriophage P21 holin S EamA PF00892.20 PSC68766.1 - 0.18 12.0 8.6 0.051 13.7 3.9 2.1 2 1 0 2 2 2 0 EamA-like transporter family DUF2062 PF09835.9 PSC68766.1 - 0.99 9.3 9.1 0.16 11.8 3.6 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2062) CytochromB561_N PF09786.9 PSC68767.1 - 3.2e-39 135.4 0.0 4.5e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome B561, N terminal TMP-TENI PF02581.17 PSC68768.1 - 1.1e-08 34.6 0.0 1.8e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase fn3 PF00041.21 PSC68768.1 - 0.0015 18.8 0.0 0.0028 18.0 0.0 1.5 1 0 0 1 1 1 1 Fibronectin type III domain RicinB_lectin_2 PF14200.6 PSC68768.1 - 0.039 14.7 0.3 0.19 12.5 0.1 2.2 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like TMP-TENI PF02581.17 PSC68769.1 - 1.5e-11 43.9 0.0 2.4e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Thiamine monophosphate synthase fn3 PF00041.21 PSC68769.1 - 0.0015 18.8 0.0 0.0028 18.0 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain RicinB_lectin_2 PF14200.6 PSC68769.1 - 0.039 14.7 0.3 0.19 12.5 0.1 2.3 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like LPMO_10 PF03067.15 PSC68770.1 - 0.00012 22.8 0.1 0.00031 21.4 0.1 1.6 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading OmdA PF13376.6 PSC68770.1 - 0.17 11.9 0.5 0.26 11.3 0.5 1.3 1 0 0 1 1 1 0 Bacteriocin-protection, YdeI or OmpD-Associated Ank_2 PF12796.7 PSC68771.1 - 2.1e-18 66.7 1.4 1.4e-09 38.4 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC68771.1 - 2e-16 60.1 0.2 0.00053 20.5 0.1 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC68771.1 - 3.3e-16 59.1 4.7 8.7e-09 35.5 0.3 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC68771.1 - 2.3e-10 39.8 7.5 0.085 13.5 0.1 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank PF00023.30 PSC68771.1 - 7.6e-08 32.5 12.9 0.056 13.9 0.0 4.9 5 0 0 5 5 5 3 Ankyrin repeat DBC1 PF14443.6 PSC68772.1 - 1.3e-31 109.2 0.0 3.3e-31 107.9 0.0 1.7 1 0 0 1 1 1 1 DBC1 DUF262 PF03235.14 PSC68772.1 - 2.9e-20 73.4 0.0 2.9e-20 73.4 0.0 2.8 4 0 0 4 4 4 1 Protein of unknown function DUF262 DUF1524 PF07510.11 PSC68772.1 - 8.6e-15 54.8 0.0 2.1e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) S1-like PF14444.6 PSC68772.1 - 5.3e-11 42.3 0.2 1.1e-10 41.2 0.2 1.6 1 0 0 1 1 1 1 S1-like G-patch PF01585.23 PSC68772.1 - 1.8e-10 40.5 0.3 4.6e-10 39.2 0.3 1.8 1 0 0 1 1 1 1 G-patch domain SAP PF02037.27 PSC68772.1 - 4.4e-06 26.3 0.6 2.3e-05 24.0 0.6 2.3 1 1 0 1 1 1 1 SAP domain G-patch_2 PF12656.7 PSC68772.1 - 0.016 15.3 1.0 0.11 12.6 0.2 2.7 2 0 0 2 2 2 0 G-patch domain Wbp11 PF09429.10 PSC68774.1 - 1.1e-14 54.6 12.3 1.6e-14 54.0 12.3 1.3 1 0 0 1 1 1 1 WW domain binding protein 11 TonB_2 PF13103.6 PSC68774.1 - 2.5 8.4 0.0 2.5 8.4 0.0 5.0 3 1 2 5 5 5 0 TonB C terminal MIR PF02815.19 PSC68775.1 - 4.1e-15 56.1 0.2 8.4e-14 51.8 0.3 2.4 1 1 1 2 2 2 2 MIR domain Beta_helix PF13229.6 PSC68776.1 - 1.5e-11 44.4 0.0 2.7e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Right handed beta helix region zf-MYND PF01753.18 PSC68776.1 - 8.9e-08 32.1 8.5 2.4e-07 30.7 8.0 2.1 1 1 1 2 2 2 1 MYND finger NosD PF05048.13 PSC68776.1 - 0.031 13.6 0.0 0.048 12.9 0.0 1.2 1 0 0 1 1 1 0 Periplasmic copper-binding protein (NosD) NDUF_C2 PF06374.11 PSC68777.1 - 0.044 13.9 0.0 0.06 13.5 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) ABC_membrane PF00664.23 PSC68778.1 - 0.0039 16.9 0.3 0.0047 16.6 0.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region MerC PF03203.14 PSC68778.1 - 0.023 15.1 2.3 0.023 15.1 2.3 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein Tryp_alpha_amyl PF00234.22 PSC68779.1 - 0.071 13.6 1.6 0.13 12.7 1.7 1.6 1 1 0 1 1 1 0 Protease inhibitor/seed storage/LTP family LTP_2 PF14368.6 PSC68779.1 - 0.11 12.7 5.4 0.23 11.6 5.4 1.7 1 1 0 1 1 1 0 Probable lipid transfer TB2_DP1_HVA22 PF03134.19 PSC68780.1 - 1.7e-25 88.7 1.4 1.7e-25 88.7 1.4 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family Pyr_redox_2 PF07992.14 PSC68781.1 - 1.9e-05 24.1 0.0 2e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PSC68781.1 - 0.00019 20.6 0.6 0.00022 20.4 0.6 1.0 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_2 PF07992.14 PSC68783.1 - 3e-21 75.9 0.0 5e-21 75.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIRS_C PF02769.22 PSC68783.1 - 6.9e-21 75.0 4.0 1.6e-20 73.8 4.0 1.6 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 PSC68783.1 - 4.1e-15 56.2 1.0 4.3e-14 52.9 1.0 2.8 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain Pyr_redox PF00070.27 PSC68783.1 - 0.00015 22.3 0.0 0.00043 20.8 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Myc_N PF01056.18 PSC68783.1 - 0.11 12.4 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Rav1p_C PF12234.8 PSC68785.1 - 8.8e-47 159.9 3.2 1.6e-37 129.3 5.6 2.1 2 0 0 2 2 2 2 RAVE protein 1 C terminal WD40 PF00400.32 PSC68785.1 - 0.086 13.7 17.3 21 6.2 0.1 8.3 8 1 0 8 8 8 0 WD domain, G-beta repeat Helicase_C PF00271.31 PSC68786.1 - 0.00018 21.8 0.1 0.00053 20.3 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OTU PF02338.19 PSC68786.1 - 0.0032 18.0 0.0 0.0078 16.7 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PSC68786.1 - 0.13 11.7 0.1 7.6 5.9 0.0 2.2 2 0 0 2 2 2 0 Peptidase C65 Otubain AUX_IAA PF02309.16 PSC68787.1 - 5.8 6.7 10.0 9.7 6.0 10.0 1.3 1 0 0 1 1 1 0 AUX/IAA family Borrelia_P83 PF05262.11 PSC68787.1 - 9 4.7 31.2 12 4.3 31.2 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein NIF PF03031.18 PSC68788.1 - 7.4e-07 29.1 0.0 0.00073 19.3 0.0 2.3 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Ribosomal_L29 PF00831.23 PSC68788.1 - 0.26 11.3 4.0 0.91 9.5 0.1 2.7 2 0 0 2 2 2 0 Ribosomal L29 protein HAD PF12710.7 PSC68788.1 - 0.48 10.8 2.8 0.28 11.6 0.3 1.9 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1336 PF07059.12 PSC68789.1 - 7e-62 209.5 0.0 1.4e-61 208.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) START PF01852.19 PSC68789.1 - 3.9e-14 52.6 0.1 9.3e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 START domain PH PF00169.29 PSC68789.1 - 0.00027 21.4 0.0 0.00052 20.5 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF2250 PF10007.9 PSC68789.1 - 0.12 12.6 1.0 0.36 11.0 0.4 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) TB2_DP1_HVA22 PF03134.19 PSC68790.1 - 2.5e-25 88.2 1.4 2.5e-25 88.2 1.4 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family TB2_DP1_HVA22 PF03134.19 PSC68791.1 - 1.7e-25 88.7 1.4 1.7e-25 88.7 1.4 1.6 2 0 0 2 2 2 1 TB2/DP1, HVA22 family GATA PF00320.27 PSC68792.1 - 3.8e-05 23.2 18.4 0.0051 16.4 5.0 3.2 3 0 0 3 3 3 2 GATA zinc finger Glycos_transf_4 PF00953.21 PSC68793.1 - 5.3e-37 127.2 12.6 5.3e-37 127.2 12.6 2.0 3 0 0 3 3 3 1 Glycosyl transferase family 4 RNA_pol_A_bac PF01000.26 PSC68794.1 - 1.4e-28 99.4 0.0 2.5e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 PSC68794.1 - 1e-21 76.1 0.0 1.3e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Baseplate PF16774.5 PSC68794.1 - 0.12 12.3 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Baseplate protein Kinesin PF00225.23 PSC68795.1 - 6.4e-111 370.5 0.0 1.2e-110 369.6 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PSC68795.1 - 2e-22 79.7 0.0 1.3e-20 73.9 0.0 2.4 1 1 0 1 1 1 1 Microtubule binding Bac_DnaA PF00308.18 PSC68795.1 - 0.0018 18.2 0.1 0.0018 18.2 0.1 1.8 2 0 0 2 2 2 1 Bacterial dnaA protein Use1 PF09753.9 PSC68795.1 - 0.0027 17.5 6.8 0.0027 17.5 6.8 2.6 2 1 1 3 3 3 1 Membrane fusion protein Use1 Kinesin_assoc PF16183.5 PSC68795.1 - 0.22 11.6 0.0 0.22 11.6 0.0 3.2 3 1 1 4 4 4 0 Kinesin-associated Jnk-SapK_ap_N PF09744.9 PSC68795.1 - 0.34 11.1 30.2 0.03 14.5 1.9 3.3 3 1 1 4 4 4 0 JNK_SAPK-associated protein-1 Fez1 PF06818.15 PSC68795.1 - 2.1 8.8 25.1 37 4.7 0.0 2.3 1 1 1 2 2 2 0 Fez1 rve PF00665.26 PSC68796.1 - 4e-19 68.9 0.0 8e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC68796.1 - 0.0054 16.5 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Hairy_orange PF07527.13 PSC68796.1 - 0.066 13.4 0.2 0.33 11.2 0.0 2.3 2 0 0 2 2 2 0 Hairy Orange Pex19 PF04614.12 PSC68797.1 - 1.1e-39 136.7 0.0 1.8e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Pex19 protein family EH_Signature PF15611.6 PSC68798.1 - 0.29 10.5 5.5 0.043 13.2 1.2 1.7 2 1 0 2 2 2 0 EH_Signature domain tRNA_Me_trans PF03054.16 PSC68799.1 - 2.5e-111 371.9 0.0 6.2e-111 370.6 0.0 1.6 1 1 0 1 1 1 1 tRNA methyl transferase Asn_synthase PF00733.21 PSC68799.1 - 0.0007 19.4 0.0 0.0012 18.6 0.0 1.4 1 0 0 1 1 1 1 Asparagine synthase NAD_synthase PF02540.17 PSC68799.1 - 0.08 12.1 0.0 6.4 5.8 0.0 2.3 2 0 0 2 2 2 0 NAD synthase QueC PF06508.13 PSC68799.1 - 0.14 11.7 0.0 0.3 10.5 0.0 1.5 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 PSC68799.1 - 0.14 11.9 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 PP-loop family Kinesin PF00225.23 PSC68800.1 - 1.8e-86 290.1 0.0 2.3e-86 289.7 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PSC68800.1 - 4.1e-14 52.8 0.0 6.8e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding UEV PF05743.13 PSC68801.1 - 3.2e-33 114.2 0.2 5.2e-33 113.5 0.2 1.3 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 PSC68801.1 - 4.2e-19 68.3 2.2 1.5e-18 66.5 0.2 2.3 2 0 0 2 2 2 1 Vps23 core domain Spc7 PF08317.11 PSC68801.1 - 0.17 10.8 4.3 0.38 9.6 4.3 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein Pex14_N PF04695.13 PSC68801.1 - 3.9 8.1 26.5 0.72 10.5 4.1 3.7 4 0 0 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FliD_N PF02465.18 PSC68801.1 - 5 7.9 10.0 3.1 8.6 2.2 2.8 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Mito_carr PF00153.27 PSC68802.1 - 8.6e-50 166.6 1.4 2.7e-18 65.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UPF0154 PF03672.13 PSC68802.1 - 0.029 14.4 1.5 0.33 11.0 0.3 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Focadhesin PF11229.8 PSC68802.1 - 0.2 9.9 0.0 0.25 9.5 0.0 1.1 1 0 0 1 1 1 0 Focadhesin Nepo_coat PF03391.15 PSC68803.1 - 0.017 14.6 0.4 0.028 13.9 0.4 1.2 1 0 0 1 1 1 0 Nepovirus coat protein, central domain DUF2162 PF09930.9 PSC68803.1 - 0.066 12.6 1.7 6.8 6.0 0.1 2.2 2 0 0 2 2 2 0 Predicted transporter (DUF2162) KR PF08659.10 PSC68804.1 - 9.7e-15 54.9 2.0 1.6e-14 54.2 2.0 1.4 1 0 0 1 1 1 1 KR domain ketoacyl-synt PF00109.26 PSC68804.1 - 3.7e-11 43.1 0.0 9.1e-11 41.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain PP-binding PF00550.25 PSC68804.1 - 1.6e-10 41.2 0.0 3.9e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site PS-DH PF14765.6 PSC68804.1 - 3.5e-08 33.0 0.2 6.9e-08 32.1 0.2 1.4 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 PSC68804.1 - 0.00069 20.0 0.0 0.0015 18.9 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Radical_SAM PF04055.21 PSC68805.1 - 2.2e-18 67.2 0.0 1.3e-17 64.7 0.0 2.1 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 PSC68805.1 - 0.0011 19.0 0.0 0.0025 17.9 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 PSC68805.1 - 0.0038 17.5 0.0 0.097 12.9 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain rve PF00665.26 PSC68806.1 - 2.5e-18 66.4 0.0 8.6e-18 64.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain PLDc_2 PF13091.6 PSC68806.1 - 1.3e-09 38.0 0.0 0.0016 18.3 0.0 3.0 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 PSC68806.1 - 9.7e-05 22.4 0.1 0.19 12.0 0.2 2.5 2 0 0 2 2 2 2 Phospholipase D Active site motif APG6_N PF17675.1 PSC68806.1 - 0.0055 17.2 5.7 0.0055 17.2 5.7 5.2 2 1 3 5 5 5 1 Apg6 coiled-coil region rve_3 PF13683.6 PSC68806.1 - 0.012 15.3 0.1 0.073 12.9 0.0 2.4 2 0 0 2 2 2 0 Integrase core domain CENP-F_leu_zip PF10473.9 PSC68806.1 - 0.018 15.1 26.1 0.33 11.0 6.5 2.9 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 BLOC1_2 PF10046.9 PSC68806.1 - 0.087 13.1 0.9 12 6.3 0.1 2.7 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SHE3 PF17078.5 PSC68806.1 - 2.4 7.8 8.2 0.15 11.8 0.2 2.4 1 1 0 2 2 2 0 SWI5-dependent HO expression protein 3 rve PF00665.26 PSC68807.1 - 0.015 15.5 0.0 0.05 13.8 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain rve PF00665.26 PSC68808.1 - 0.021 15.0 0.0 0.049 13.8 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain rve PF00665.26 PSC68809.1 - 0.0093 16.2 0.0 0.05 13.8 0.0 2.0 1 1 1 2 2 2 1 Integrase core domain ABC_membrane PF00664.23 PSC68810.1 - 8.8e-53 179.7 0.1 1.1e-52 179.4 0.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PSC68810.1 - 2.5e-35 122.0 0.0 3.9e-35 121.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 PSC68810.1 - 4e-05 24.1 0.1 7.9e-05 23.1 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 PSC68810.1 - 6.7e-05 22.4 0.0 0.069 12.6 0.0 2.3 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PSC68810.1 - 0.00023 20.9 0.0 0.00053 19.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 PSC68810.1 - 0.001 19.0 0.0 0.072 12.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system ABC_ATPase PF09818.9 PSC68810.1 - 0.0012 17.7 0.0 0.0066 15.3 0.0 1.9 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 PSC68810.1 - 0.0029 17.9 0.0 0.01 16.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 PSC68810.1 - 0.0085 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_30 PF13604.6 PSC68810.1 - 0.01 15.6 0.1 0.032 13.9 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 PSC68810.1 - 0.063 12.8 0.0 0.21 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PSC68810.1 - 0.068 13.2 0.1 0.19 11.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_15 PF13175.6 PSC68810.1 - 0.083 12.6 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_23 PF13476.6 PSC68810.1 - 0.089 13.3 0.0 0.13 12.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 PSC68810.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.5 1 1 0 1 1 1 0 DEAD/DEAH box helicase APS_kinase PF01583.20 PSC68810.1 - 0.14 12.0 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase DUF87 PF01935.17 PSC68810.1 - 0.16 12.0 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain Pyr_redox_dim PF02852.22 PSC68811.1 - 3.8e-32 110.8 0.1 5.4e-32 110.3 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox_2 PF07992.14 PSC68811.1 - 7.5e-16 58.2 0.1 1.2e-15 57.5 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Metallophos PF00149.28 PSC68812.1 - 1.3e-34 120.5 0.1 1.6e-34 120.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase AMP-binding PF00501.28 PSC68813.1 - 4.5e-93 312.1 0.0 6e-93 311.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme DUF1664 PF07889.12 PSC68816.1 - 3.4e-09 36.8 4.4 0.9 9.6 0.0 4.5 4 0 0 4 4 4 4 Protein of unknown function (DUF1664) DUF3482 PF11981.8 PSC68816.1 - 6.7e-09 35.5 9.8 0.32 10.4 0.2 4.4 4 0 0 4 4 4 4 Domain of unknown function (DUF3482) Baculo_PEP_C PF04513.12 PSC68816.1 - 1.1e-07 32.0 11.0 0.14 12.2 1.4 4.2 4 0 0 4 4 4 4 Baculovirus polyhedron envelope protein, PEP, C terminus FliD_C PF07195.12 PSC68816.1 - 3.3e-07 30.0 2.2 0.33 10.3 0.2 4.1 4 0 0 4 4 4 1 Flagellar hook-associated protein 2 C-terminus DUF2730 PF10805.8 PSC68816.1 - 1.1e-06 28.6 0.0 4.2 7.5 0.0 4.3 4 0 0 4 4 4 1 Protein of unknown function (DUF2730) DUF2203 PF09969.9 PSC68816.1 - 1.1e-06 29.3 1.3 4 8.2 0.0 4.4 4 0 0 4 4 4 2 Uncharacterized conserved protein (DUF2203) Phage_Mu_Gam PF07352.12 PSC68816.1 - 3.1e-06 27.2 2.6 0.24 11.3 0.2 4.1 4 0 0 4 4 4 1 Bacteriophage Mu Gam like protein Peptidase_S31 PF05578.12 PSC68816.1 - 1.5e-05 24.6 5.5 2.4 7.6 0.1 4.1 4 0 0 4 4 4 1 Pestivirus NS3 polyprotein peptidase S31 DUF16 PF01519.16 PSC68816.1 - 2.5e-05 24.7 3.6 4.6 7.8 0.3 4.3 4 0 0 4 4 4 0 Protein of unknown function DUF16 DUF1283 PF06932.11 PSC68816.1 - 3.1e-05 24.1 3.3 20 5.5 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF1283) NPV_P10 PF05531.12 PSC68816.1 - 0.00013 22.3 14.7 6.8 7.2 0.1 5.1 4 1 0 4 4 4 0 Nucleopolyhedrovirus P10 protein DUF4235 PF14019.6 PSC68816.1 - 0.00024 21.1 17.5 0.97 9.6 0.2 5.2 4 0 0 4 4 4 3 Protein of unknown function (DUF4235) TssO PF17561.2 PSC68816.1 - 0.0004 20.5 6.5 0.81 9.8 0.4 4.1 4 0 0 4 4 4 1 Type VI secretion system, TssO DUF1640 PF07798.11 PSC68816.1 - 0.00042 20.4 20.5 1.6 8.8 1.4 6.0 4 4 1 5 5 5 2 Protein of unknown function (DUF1640) Gp58 PF07902.11 PSC68816.1 - 0.00052 18.5 6.3 0.92 7.7 0.2 4.0 4 0 0 4 4 4 1 gp58-like protein Spectrin PF00435.21 PSC68816.1 - 0.00087 19.8 2.4 9 6.8 0.0 4.4 4 0 0 4 4 4 0 Spectrin repeat VPS38 PF17649.1 PSC68816.1 - 0.0015 17.5 12.0 1.9 7.2 0.5 4.0 4 0 0 4 4 4 2 Vacuolar protein sorting 38 Remorin_C PF03763.13 PSC68816.1 - 0.0019 18.0 5.2 15 5.5 1.3 4.5 4 1 0 4 4 4 0 Remorin, C-terminal region Apolipoprotein PF01442.18 PSC68816.1 - 0.002 18.1 12.7 0.19 11.6 0.3 4.1 4 0 0 4 4 4 1 Apolipoprotein A1/A4/E domain DUF3782 PF12644.7 PSC68816.1 - 0.002 18.2 1.7 60 3.9 0.0 4.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3782) Exonuc_VII_L PF02601.15 PSC68816.1 - 0.0066 16.1 9.0 6.6 6.2 0.4 4.0 4 0 0 4 4 4 0 Exonuclease VII, large subunit CCDC158 PF15921.5 PSC68816.1 - 0.0083 14.0 9.6 4.3 5.0 0.4 4.1 4 0 0 4 4 4 1 Coiled-coil domain-containing protein 158 CCDC-167 PF15188.6 PSC68816.1 - 0.011 16.0 1.9 44 4.5 0.1 4.3 4 0 0 4 4 4 0 Coiled-coil domain-containing protein 167 ABA_WDS PF02496.16 PSC68816.1 - 0.016 15.7 7.7 59 4.2 0.1 5.1 4 0 0 4 4 4 0 ABA/WDS induced protein HSBP1 PF06825.12 PSC68816.1 - 0.021 14.7 13.3 3.4 7.6 0.3 5.5 5 0 0 5 5 4 0 Heat shock factor binding protein 1 DUF4307 PF14155.6 PSC68816.1 - 0.034 14.0 10.4 11 5.9 0.2 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4307) P68HR PF08061.11 PSC68816.1 - 0.05 13.7 0.1 2.5e+02 1.9 0.0 4.3 4 0 0 4 4 4 0 P68HR (NUC004) repeat Tektin PF03148.14 PSC68816.1 - 0.053 12.3 16.8 0.43 9.3 0.3 4.2 4 0 0 4 4 4 0 Tektin family Fzo_mitofusin PF04799.13 PSC68816.1 - 0.077 12.5 8.7 2.3 7.8 0.2 4.0 4 0 0 4 4 4 0 fzo-like conserved region DUF2220 PF09983.9 PSC68816.1 - 0.12 11.7 0.8 53 3.1 0.0 3.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria C-term(DUF2220) Syntaxin PF00804.25 PSC68816.1 - 0.17 11.6 7.4 17 5.0 1.1 4.0 4 0 0 4 4 4 0 Syntaxin DUF3726 PF12525.8 PSC68816.1 - 0.45 10.7 2.7 12 6.1 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3726) IL6 PF00489.17 PSC68816.1 - 0.54 9.8 14.6 5 6.7 0.2 4.0 4 0 0 4 4 4 0 Interleukin-6/G-CSF/MGF family Phasin PF05597.11 PSC68816.1 - 0.65 10.0 6.2 11 6.0 0.3 4.1 4 0 0 4 4 4 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF3740 PF12548.8 PSC68816.1 - 1 9.8 11.0 76 3.7 0.1 4.3 4 0 0 4 4 4 0 Sulfatase protein CopD PF05425.13 PSC68816.1 - 1.3 9.5 22.7 15 6.1 0.9 4.5 4 0 0 4 4 4 0 Copper resistance protein D Fib_alpha PF08702.10 PSC68816.1 - 2 8.6 12.1 4.3 7.5 0.4 4.2 4 0 0 4 4 4 0 Fibrinogen alpha/beta chain family SlyX PF04102.12 PSC68816.1 - 2.6 8.7 18.7 23 5.7 0.4 5.3 4 3 0 4 4 4 0 SlyX PfUIS3 PF11567.8 PSC68816.1 - 2.8 8.4 7.8 14 6.1 0.6 3.7 4 0 0 4 4 4 0 Plasmodium falciparum UIS3 membrane protein RmuC PF02646.16 PSC68816.1 - 6.6 5.8 6.9 36 3.3 0.1 3.7 4 0 0 4 4 4 0 RmuC family Dak1_2 PF13684.6 PSC68816.1 - 7.9 5.5 11.7 27 3.7 0.2 3.9 4 0 0 4 4 4 0 Dihydroxyacetone kinase family TPR_1 PF00515.28 PSC68817.1 - 1.8e-14 52.8 9.6 7.6e-08 31.9 0.5 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PSC68817.1 - 8.4e-14 50.5 11.5 6.2e-07 29.0 0.7 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 PSC68817.1 - 1.2e-12 47.0 7.6 2.3e-06 27.4 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PSC68817.1 - 2.6e-11 43.0 12.2 4.3e-10 39.1 2.9 3.4 1 1 2 3 3 3 3 TPR repeat TPR_16 PF13432.6 PSC68817.1 - 7.2e-10 39.4 4.3 7.2e-10 39.4 4.3 4.5 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 PSC68817.1 - 1.2e-08 35.1 6.2 0.001 19.3 0.5 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 PSC68817.1 - 1.3e-07 31.1 2.5 0.00046 20.0 0.2 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 PSC68817.1 - 1.9e-06 27.8 5.5 0.0012 19.1 0.1 3.5 3 1 0 4 4 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 PSC68817.1 - 0.00036 21.0 2.8 0.00036 21.0 2.8 3.0 2 1 0 3 3 2 1 Tetratricopeptide repeat TPR_10 PF13374.6 PSC68817.1 - 0.00042 20.1 4.5 0.072 13.0 0.3 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 PSC68817.1 - 0.00088 19.9 19.0 0.0015 19.2 0.0 4.7 3 2 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 PSC68817.1 - 0.0051 17.4 8.7 0.67 10.7 0.3 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 PSC68817.1 - 0.0074 16.4 0.2 0.031 14.4 0.2 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat FAT PF02259.23 PSC68817.1 - 0.015 14.5 0.5 0.021 14.0 0.5 1.2 1 0 0 1 1 1 0 FAT domain SHNi-TPR PF10516.9 PSC68817.1 - 0.15 11.5 0.8 0.92 9.0 0.0 2.4 2 0 0 2 2 2 0 SHNi-TPR BTAD PF03704.17 PSC68817.1 - 6.5 7.2 15.2 0.19 12.2 0.8 3.2 2 2 1 3 3 3 0 Bacterial transcriptional activator domain TRAM_LAG1_CLN8 PF03798.16 PSC68818.1 - 3e-09 36.9 13.4 3e-09 36.9 13.4 1.6 2 0 0 2 2 2 1 TLC domain DUF2967 PF11179.8 PSC68818.1 - 0.002 16.3 3.2 0.0031 15.7 3.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2967) bZIP_1 PF00170.21 PSC68818.1 - 0.52 10.5 11.6 1.3 9.2 11.6 1.7 1 0 0 1 1 1 0 bZIP transcription factor DUF3676 PF12429.8 PSC68818.1 - 5.7 6.7 7.1 0.5 10.2 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3676) Chorismate_bind PF00425.18 PSC68819.1 - 9.7e-52 176.1 0.0 2.8e-47 161.5 0.0 2.3 2 0 0 2 2 2 2 chorismate binding enzyme TPP_enzyme_N PF02776.18 PSC68819.1 - 8.4e-36 123.2 0.5 4.8e-35 120.7 0.5 2.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain MR_MLE_C PF13378.6 PSC68819.1 - 4.6e-21 75.4 3.1 4.6e-21 75.4 3.1 3.9 4 0 0 4 4 4 1 Enolase C-terminal domain-like TPP_enzyme_M_2 PF16582.5 PSC68819.1 - 1.8e-15 57.2 2.2 5e-12 46.0 0.2 3.2 2 2 0 2 2 2 2 Middle domain of thiamine pyrophosphate Abhydrolase_1 PF00561.20 PSC68819.1 - 2.2e-14 53.7 0.0 1.1e-13 51.4 0.0 2.3 2 1 0 2 2 2 1 alpha/beta hydrolase fold Esterase PF00756.20 PSC68819.1 - 0.00063 19.5 0.6 0.0014 18.4 0.6 1.5 1 0 0 1 1 1 1 Putative esterase Peptidase_M55 PF04951.13 PSC68819.1 - 6.6 6.0 7.1 1 8.7 0.0 2.9 4 0 0 4 4 4 0 D-aminopeptidase TRM PF02005.16 PSC68820.1 - 9.8e-121 403.5 0.0 1.3e-120 403.1 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 PSC68820.1 - 0.027 14.2 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein TRM PF02005.16 PSC68821.1 - 1.1e-120 403.3 0.0 1.3e-120 403.0 0.0 1.0 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Met_10 PF02475.16 PSC68821.1 - 0.027 14.2 0.0 0.044 13.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Hydrolase_3 PF08282.12 PSC68822.1 - 1.4e-37 129.8 0.0 2e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase UPF0054 PF02130.17 PSC68822.1 - 4.8e-36 123.4 0.1 6.9e-36 122.9 0.1 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0054 S6PP PF05116.13 PSC68822.1 - 1.4e-09 37.9 0.1 1.5e-06 28.0 0.0 2.2 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 PSC68822.1 - 2.2e-05 24.9 2.5 0.18 12.1 0.1 3.4 2 1 1 3 3 3 3 haloacid dehalogenase-like hydrolase HAD PF12710.7 PSC68822.1 - 0.0018 18.7 3.1 4.3 7.7 0.0 3.6 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase DUF4350 PF14258.6 PSC68822.1 - 0.019 15.4 0.6 0.14 12.6 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) Hydrolase_6 PF13344.6 PSC68822.1 - 0.022 14.8 0.0 0.06 13.5 0.0 1.7 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Chorion_3 PF05387.11 PSC68822.1 - 0.99 9.0 5.3 2 8.0 5.3 1.4 1 0 0 1 1 1 0 Chorion family 3 TENA_THI-4 PF03070.16 PSC68823.1 - 3e-19 69.7 0.4 3.4e-19 69.5 0.4 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family DNAPolymera_Pol PF11590.8 PSC68823.1 - 0.09 12.7 1.0 0.18 11.7 1.0 1.5 1 0 0 1 1 1 0 DNA polymerase catalytic subunit Pol HA2 PF04408.23 PSC68824.1 - 3.6e-18 65.8 0.1 3.6e-18 65.8 0.1 3.7 3 1 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PSC68824.1 - 6.1e-16 58.5 0.0 1.2e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PSC68824.1 - 1.4e-08 35.0 0.0 3.2e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PSC68824.1 - 8.3e-07 28.9 0.0 1.6e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_19 PF13245.6 PSC68824.1 - 0.002 18.5 0.0 0.011 16.1 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PSC68824.1 - 0.0057 16.9 0.1 0.03 14.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain T2SSE PF00437.20 PSC68824.1 - 0.006 15.7 0.1 0.019 14.1 0.1 1.8 1 1 0 1 1 1 1 Type II/IV secretion system protein ATPase PF06745.13 PSC68824.1 - 0.2 11.0 1.4 0.28 10.5 0.0 1.9 2 0 0 2 2 2 0 KaiC DND1_DSRM PF14709.7 PSC68824.1 - 1.6 9.0 4.7 4.1 7.7 0.0 3.8 3 0 0 3 3 3 0 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_11 PF13086.6 PSC68824.1 - 3 7.6 0.0 3 7.6 0.0 3.6 3 2 0 3 3 3 0 AAA domain HHH_5 PF14520.6 PSC68825.1 - 0.094 13.3 4.6 12 6.6 0.0 4.1 3 0 0 3 3 3 0 Helix-hairpin-helix domain SurE PF01975.17 PSC68826.1 - 3e-47 160.9 0.1 4.2e-47 160.5 0.1 1.1 1 0 0 1 1 1 1 Survival protein SurE PI3_PI4_kinase PF00454.27 PSC68827.1 - 8.2e-21 74.9 0.0 1.1e-20 74.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase MDMPI_N PF11716.8 PSC68828.1 - 0.0066 17.1 5.0 0.0092 16.7 5.0 1.4 1 0 0 1 1 1 1 Mycothiol maleylpyruvate isomerase N-terminal domain Baculo_PEP_C PF04513.12 PSC68828.1 - 0.011 15.8 0.5 0.014 15.4 0.5 1.2 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.12 PSC68828.1 - 0.013 15.5 0.1 0.018 15.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HlyD_2 PF12700.7 PSC68828.1 - 0.052 12.3 0.1 0.06 12.1 0.1 1.0 1 0 0 1 1 1 0 HlyD family secretion protein DUF1640 PF07798.11 PSC68828.1 - 0.15 12.1 2.9 3 7.9 0.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) MINDY_DUB PF04424.13 PSC68829.1 - 3.1e-35 120.7 0.0 5.7e-35 119.9 0.0 1.5 1 0 0 1 1 1 1 MINDY deubiquitinase SH2 PF00017.24 PSC68829.1 - 0.0012 18.9 0.0 0.0024 17.9 0.0 1.5 1 0 0 1 1 1 1 SH2 domain CPSase_sm_chain PF00988.22 PSC68830.1 - 8.1e-50 167.9 0.0 1.3e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase small chain, CPSase domain peroxidase PF00141.23 PSC68830.1 - 2.7e-44 151.6 0.0 4.2e-44 150.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase GATase PF00117.28 PSC68830.1 - 5.1e-42 143.8 0.0 8.2e-42 143.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 PSC68830.1 - 0.00012 22.0 0.3 0.00072 19.4 0.3 2.2 1 1 0 1 1 1 1 Peptidase C26 DUF21 PF01595.20 PSC68831.1 - 3e-38 131.3 0.4 1.3e-37 129.2 0.1 2.1 2 0 0 2 2 2 1 Cyclin M transmembrane N-terminal domain SNARE_assoc PF09335.11 PSC68831.1 - 5.2e-18 65.7 3.8 6.4e-18 65.4 2.0 2.2 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF5437 PF17505.2 PSC68831.1 - 1.6 8.8 9.7 0.78 9.8 0.2 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5437) Abhydrolase_6 PF12697.7 PSC68832.1 - 1.9e-22 81.0 6.3 2.6e-22 80.5 6.3 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PSC68832.1 - 3.2e-20 72.4 0.0 5.6e-20 71.6 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PSC68832.1 - 4.7e-17 62.5 0.1 4.3e-15 56.1 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold UPF0227 PF05728.12 PSC68832.1 - 0.00041 20.3 0.0 0.066 13.2 0.2 2.9 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0227) Ndr PF03096.14 PSC68832.1 - 0.0014 17.4 0.0 0.015 14.0 0.0 2.0 1 1 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.7 PSC68832.1 - 0.0014 18.5 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 2 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 PSC68832.1 - 0.0064 16.4 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_4 PF08386.10 PSC68832.1 - 0.0068 16.5 0.0 0.012 15.7 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Thioesterase PF00975.20 PSC68832.1 - 0.045 13.9 0.0 0.18 11.9 0.0 1.9 1 1 0 1 1 1 0 Thioesterase domain FSH1 PF03959.13 PSC68832.1 - 0.095 12.3 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) PhoPQ_related PF10142.9 PSC68832.1 - 0.29 9.7 0.0 0.41 9.3 0.0 1.1 1 0 0 1 1 1 0 PhoPQ-activated pathogenicity-related protein WD40 PF00400.32 PSC68833.1 - 1.5e-06 28.8 0.0 0.19 12.6 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF4504 PF14953.6 PSC68834.1 - 7.2e-13 48.5 0.0 2.9e-05 23.6 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4504) L31 PF09784.9 PSC68835.1 - 0.11 13.0 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L31 Inhibitor_I9 PF05922.16 PSC68835.1 - 0.16 12.6 0.4 13 6.6 0.0 2.0 1 1 0 2 2 2 0 Peptidase inhibitor I9 UPF0225 PF17775.1 PSC68836.1 - 4.6e-28 97.9 0.0 6.7e-28 97.4 0.0 1.2 1 0 0 1 1 1 1 UPF0225 domain SEC-C PF02810.15 PSC68836.1 - 3.6e-05 23.6 5.6 3.6e-05 23.6 5.6 2.1 2 0 0 2 2 2 1 SEC-C motif DUF4510 PF14971.6 PSC68836.1 - 0.02 15.2 0.9 0.033 14.5 0.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) DUF543 PF04418.12 PSC68836.1 - 0.57 10.2 3.3 3.4 7.7 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) UPF0225 PF17775.1 PSC68837.1 - 3.8e-24 85.4 0.0 1.5e-23 83.5 0.0 1.8 1 1 0 1 1 1 1 UPF0225 domain SEC-C PF02810.15 PSC68837.1 - 3.9e-05 23.5 5.6 3.9e-05 23.5 5.6 2.2 2 0 0 2 2 2 1 SEC-C motif DUF4510 PF14971.6 PSC68837.1 - 0.027 14.8 1.0 0.042 14.2 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4510) DUF543 PF04418.12 PSC68837.1 - 0.67 10.0 3.3 3.7 7.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) SNF2_N PF00176.23 PSC68838.1 - 1.3e-58 198.5 0.0 2e-58 197.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC68838.1 - 9.6e-17 61.3 0.0 2.3e-16 60.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC68838.1 - 1.4e-05 25.1 0.0 2.5e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CPW_WPC PF09717.10 PSC68838.1 - 0.0031 18.5 0.2 5.7 8.0 0.1 2.4 2 0 0 2 2 2 2 Plasmodium falciparum domain of unknown function (CPW_WPC) Apolipoprotein PF01442.18 PSC68839.1 - 0.00043 20.2 0.6 0.00096 19.1 0.5 1.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF16 PF01519.16 PSC68839.1 - 0.0085 16.6 5.5 0.73 10.4 0.2 2.3 1 1 1 2 2 2 2 Protein of unknown function DUF16 Phage_Mu_Gam PF07352.12 PSC68839.1 - 0.033 14.1 4.7 0.59 10.0 0.2 2.1 1 1 1 2 2 2 0 Bacteriophage Mu Gam like protein Spectrin PF00435.21 PSC68839.1 - 0.067 13.7 0.6 0.15 12.6 0.5 1.6 1 1 0 1 1 1 0 Spectrin repeat LPD39 PF18858.1 PSC68839.1 - 0.092 12.8 5.2 0.2 11.7 5.1 1.6 1 1 0 1 1 1 0 Large polyvalent protein associated domain 39 Phasin PF05597.11 PSC68839.1 - 0.098 12.7 3.6 1.1 9.3 2.4 2.2 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) TssO PF17561.2 PSC68839.1 - 0.11 12.6 6.4 0.3 11.2 0.3 2.2 1 1 1 2 2 2 0 Type VI secretion system, TssO KxDL PF10241.9 PSC68839.1 - 0.11 12.7 1.0 3.9 7.8 0.2 2.5 1 1 2 3 3 3 0 Uncharacterized conserved protein DUF3450 PF11932.8 PSC68839.1 - 0.16 11.2 4.9 0.46 9.7 3.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) NPV_P10 PF05531.12 PSC68839.1 - 0.2 12.2 9.8 3.2 8.3 2.5 3.0 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 PSC68839.1 - 0.2 11.7 8.6 0.52 10.3 7.8 1.9 1 1 2 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Muted PF14942.6 PSC68839.1 - 0.2 12.0 3.6 0.35 11.2 3.5 1.5 1 1 0 1 1 1 0 Organelle biogenesis, Muted-like protein ABC_tran_CTD PF16326.5 PSC68839.1 - 0.2 11.9 0.2 4.3 7.7 0.0 2.7 1 1 3 4 4 4 0 ABC transporter C-terminal domain DUF1690 PF07956.11 PSC68839.1 - 0.24 11.8 2.4 0.4 11.1 2.4 1.4 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF1664 PF07889.12 PSC68839.1 - 0.29 11.2 4.5 11 6.1 3.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Fzo_mitofusin PF04799.13 PSC68839.1 - 0.35 10.4 0.8 2.1 7.9 0.2 1.9 1 1 1 2 2 2 0 fzo-like conserved region DUF1640 PF07798.11 PSC68839.1 - 0.47 10.5 9.1 8.4 6.4 8.3 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Taxilin PF09728.9 PSC68839.1 - 0.55 9.4 5.5 4.1 6.5 5.5 1.9 1 1 0 1 1 1 0 Myosin-like coiled-coil protein DUF948 PF06103.11 PSC68839.1 - 0.66 10.3 10.3 47 4.3 9.0 3.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Beta_helix_2 PF18835.1 PSC68839.1 - 0.93 9.3 5.1 11 5.9 0.4 2.4 1 1 1 2 2 2 0 Beta helix repeat of Inulin fructotransferase PIN_4 PF13638.6 PSC68839.1 - 1.8 8.9 9.6 15 5.9 9.6 2.1 1 1 0 1 1 1 0 PIN domain DUF4407 PF14362.6 PSC68839.1 - 1.8 7.9 12.5 1.6 8.0 11.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) UPRTase PF14681.6 PSC68841.1 - 1.3e-68 230.5 0.0 2.1e-68 229.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 PSC68841.1 - 3.8e-40 137.7 1.6 5.7e-40 137.2 1.6 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Pribosyltran PF00156.27 PSC68841.1 - 0.00037 20.0 0.0 0.001 18.6 0.0 1.6 1 1 1 2 2 2 1 Phosphoribosyl transferase domain Phasin_2 PF09361.10 PSC68841.1 - 0.025 14.8 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 Phasin protein AAA_18 PF13238.6 PSC68841.1 - 0.08 13.5 0.4 0.17 12.5 0.4 1.5 1 0 0 1 1 1 0 AAA domain PARG_cat PF05028.14 PSC68841.1 - 0.18 11.1 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Poly (ADP-ribose) glycohydrolase (PARG) PhoD PF09423.10 PSC68842.1 - 2.2e-15 56.5 0.0 1.2e-12 47.6 0.0 2.5 3 0 0 3 3 3 2 PhoD-like phosphatase TGBp3 PF02495.17 PSC68842.1 - 0.074 12.7 2.4 0.34 10.6 0.0 2.3 2 0 0 2 2 2 0 Triple gene block 3 Spc7 PF08317.11 PSC68843.1 - 0.0053 15.7 4.1 0.0053 15.7 4.1 3.6 1 1 2 4 4 4 3 Spc7 kinetochore protein Fib_alpha PF08702.10 PSC68843.1 - 0.013 15.7 4.7 4 7.6 0.1 3.6 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family DUF724 PF05266.14 PSC68843.1 - 0.018 14.9 3.9 0.018 14.9 3.9 4.1 1 1 3 4 4 4 0 Protein of unknown function (DUF724) PriC PF07445.12 PSC68843.1 - 0.053 13.4 46.6 0.17 11.8 2.5 4.3 1 1 2 4 4 4 0 Primosomal replication protein priC DUF2730 PF10805.8 PSC68843.1 - 0.085 13.0 6.6 0.16 12.1 0.3 4.0 4 2 0 4 4 4 0 Protein of unknown function (DUF2730) DUF1664 PF07889.12 PSC68843.1 - 0.16 12.0 15.8 0.53 10.3 0.3 5.1 2 1 1 5 5 5 0 Protein of unknown function (DUF1664) TBCA PF02970.16 PSC68843.1 - 0.19 12.1 26.7 0.039 14.3 3.2 5.4 3 2 2 5 5 5 0 Tubulin binding cofactor A Kinesin_assoc PF16183.5 PSC68843.1 - 0.37 10.9 12.3 0.033 14.3 5.6 2.6 1 1 1 3 3 3 0 Kinesin-associated DUF16 PF01519.16 PSC68843.1 - 3.5 8.2 15.6 6.2 7.4 0.9 4.7 3 1 1 4 4 4 0 Protein of unknown function DUF16 Na_H_Exchanger PF00999.21 PSC68844.1 - 2.6e-30 105.5 35.2 4.2e-30 104.8 35.2 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family cNMP_binding PF00027.29 PSC68844.1 - 0.099 12.7 0.0 0.68 10.0 0.0 2.3 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain SMG1 PF15785.5 PSC68845.1 - 1.3e-25 89.9 17.0 2.1e-23 82.6 1.5 3.2 3 0 0 3 3 3 3 Serine/threonine-protein kinase smg-1 PI3_PI4_kinase PF00454.27 PSC68845.1 - 5.9e-08 32.8 0.0 9.5e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 PSC68845.1 - 0.064 13.7 2.4 5.3 7.5 0.1 2.7 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain DUF3389 PF11869.8 PSC68845.1 - 0.37 11.0 2.7 1.1 9.5 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3389) WPP PF13943.6 PSC68845.1 - 6.1 7.3 8.3 0.14 12.5 0.1 2.6 2 0 0 2 2 2 0 WPP domain FAD_binding_4 PF01565.23 PSC68846.1 - 3.2e-19 69.0 5.9 5.7e-19 68.2 5.9 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 PSC68846.1 - 1.5e-07 31.4 0.2 3e-07 30.4 0.2 1.5 1 0 0 1 1 1 1 Berberine and berberine like Methyltransf_16 PF10294.9 PSC68847.1 - 5.5e-11 42.5 0.0 3.8e-08 33.3 0.0 2.3 2 0 0 2 2 2 2 Lysine methyltransferase Thi4 PF01946.17 PSC68848.1 - 7.9e-102 339.5 0.4 9.5e-102 339.2 0.4 1.1 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 PSC68848.1 - 1.9e-08 34.3 4.0 1e-07 31.9 1.1 2.2 1 1 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PSC68848.1 - 5.7e-08 32.9 0.5 1.6e-07 31.4 0.5 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 PSC68848.1 - 3.2e-07 29.8 3.8 4e-05 22.9 1.2 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 PSC68848.1 - 8.3e-06 25.2 0.4 2.2e-05 23.8 0.3 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 PSC68848.1 - 0.00074 18.9 0.1 0.0013 18.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 PSC68848.1 - 0.00077 18.3 0.6 0.0013 17.5 0.6 1.3 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 PSC68848.1 - 0.00084 18.7 0.4 0.0013 18.0 0.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 PSC68848.1 - 0.0012 18.3 0.1 0.26 10.6 0.0 2.2 2 0 0 2 2 2 2 GMC oxidoreductase FAD_oxidored PF12831.7 PSC68848.1 - 0.0013 18.2 0.4 0.0013 18.2 0.4 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 PSC68848.1 - 0.003 16.7 1.9 0.003 16.7 1.9 2.7 2 1 0 2 2 2 1 Lycopene cyclase protein NAD_binding_9 PF13454.6 PSC68848.1 - 0.0084 16.1 1.0 0.018 15.0 0.0 2.1 3 0 0 3 3 3 1 FAD-NAD(P)-binding GIDA PF01134.22 PSC68848.1 - 0.22 10.6 1.9 0.27 10.3 0.9 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A Josephin PF02099.17 PSC68849.1 - 1.4e-48 165.1 0.0 2.8e-48 164.1 0.0 1.5 2 0 0 2 2 2 1 Josephin UBX PF00789.20 PSC68849.1 - 0.00014 22.0 0.0 0.00026 21.1 0.0 1.3 1 0 0 1 1 1 1 UBX domain UIM PF02809.20 PSC68849.1 - 0.00062 19.5 12.9 0.028 14.3 4.6 3.4 3 0 0 3 3 3 2 Ubiquitin interaction motif Pex14_N PF04695.13 PSC68849.1 - 0.034 14.8 9.1 0.062 14.0 9.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PA28_alpha PF02251.18 PSC68849.1 - 0.066 13.3 0.0 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit TFIIA PF03153.13 PSC68849.1 - 0.072 13.1 12.9 0.094 12.7 12.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mito_fiss_reg PF05308.11 PSC68850.1 - 0.4 10.7 3.1 0.68 10.0 3.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator 2-oxoacid_dh PF00198.23 PSC68851.1 - 6.5e-80 267.9 0.0 8.7e-80 267.5 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 PSC68851.1 - 5.3e-40 135.1 0.9 2.7e-20 71.9 0.2 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.17 PSC68851.1 - 2.5e-12 46.9 0.8 8e-12 45.3 0.8 2.0 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 PSC68851.1 - 6e-09 35.6 0.0 0.002 17.9 0.0 2.8 2 0 0 2 2 2 2 Biotin-lipoyl like QRPTase_N PF02749.16 PSC68851.1 - 9.3e-05 22.4 0.0 0.42 10.7 0.0 2.6 2 0 0 2 2 2 2 Quinolinate phosphoribosyl transferase, N-terminal domain HlyD_3 PF13437.6 PSC68851.1 - 0.0007 20.3 0.6 2.8 8.7 0.0 3.8 2 1 1 3 3 3 1 HlyD family secretion protein PTS_EIIA_1 PF00358.20 PSC68851.1 - 0.034 13.9 0.0 4.9 6.9 0.0 2.4 2 0 0 2 2 2 0 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 ATP-synt_ab_Xtn PF16886.5 PSC68851.1 - 0.039 13.8 0.1 6.8 6.6 0.0 2.4 2 0 0 2 2 2 0 ATPsynthase alpha/beta subunit N-term extension DUF3421 PF11901.8 PSC68851.1 - 0.046 13.7 0.0 5.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3421) DUF1631 PF07793.11 PSC68851.1 - 2.4 6.5 11.3 0.066 11.6 4.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) Peptidase_S8 PF00082.22 PSC68852.1 - 2.5e-38 132.1 4.2 2.5e-38 132.1 4.2 2.0 2 0 0 2 2 2 1 Subtilase family Methyltransf_23 PF13489.6 PSC68852.1 - 1.7e-18 67.0 0.0 8.4e-18 64.7 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC68852.1 - 9.4e-08 32.6 0.0 6e-06 26.8 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC68852.1 - 1.5e-06 28.8 0.0 0.003 18.2 0.0 2.9 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 PSC68852.1 - 4.3e-05 23.0 0.0 0.0001 21.7 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 PSC68852.1 - 9.3e-05 23.1 0.0 0.15 12.9 0.0 2.6 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 PSC68852.1 - 0.00039 20.2 0.0 0.00084 19.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Amino_oxidase PF01593.24 PSC68853.1 - 4.8e-13 49.2 0.5 2.4e-12 46.9 0.2 2.1 2 1 1 3 3 3 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PSC68853.1 - 2.9e-09 37.0 1.1 5.1e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 PSC68853.1 - 1.2e-05 24.6 4.6 0.00067 18.8 2.3 2.3 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 PSC68853.1 - 1.4e-05 24.4 0.1 0.00016 21.0 0.2 2.1 2 0 0 2 2 2 1 Thi4 family DAO PF01266.24 PSC68853.1 - 3.4e-05 23.6 6.2 0.21 11.1 1.9 3.4 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PSC68853.1 - 4.5e-05 22.8 0.2 0.00043 19.6 0.1 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PSC68853.1 - 0.0002 20.6 1.3 0.00073 18.7 0.9 1.9 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 PSC68853.1 - 0.00032 20.0 0.4 0.0012 18.2 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 PSC68853.1 - 0.00035 19.4 1.7 0.00096 18.0 0.6 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 PSC68853.1 - 0.00043 19.8 0.9 0.00087 18.7 0.9 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase YjeF_N PF03853.15 PSC68853.1 - 0.006 16.5 0.3 0.011 15.7 0.3 1.4 1 0 0 1 1 1 1 YjeF-related protein N-terminus Pyr_redox PF00070.27 PSC68853.1 - 0.18 12.3 0.9 2.4 8.8 0.8 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 PSC68853.1 - 2.1 7.6 5.9 0.17 11.1 0.6 1.8 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Sulfate_transp PF00916.20 PSC68854.1 - 2.1e-16 59.7 21.0 3.4e-16 59.0 21.0 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 PSC68854.1 - 4.6e-06 26.2 0.0 9.8e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.29 PSC68854.1 - 9.6e-06 25.6 0.1 0.0042 17.1 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain MTS PF05175.14 PSC68856.1 - 6e-06 25.9 0.0 1.9e-05 24.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 PSC68856.1 - 6.5e-05 22.8 0.0 0.00019 21.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 PSC68856.1 - 0.00014 21.4 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PSC68856.1 - 0.00024 21.7 0.0 0.001 19.7 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC68856.1 - 0.00045 20.8 0.1 0.012 16.3 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain PrmC_N PF17827.1 PSC68856.1 - 0.0053 17.3 0.2 0.023 15.3 0.1 2.2 2 0 0 2 2 2 1 PrmC N-terminal domain Methyltransf_24 PF13578.6 PSC68856.1 - 0.042 14.9 0.0 0.17 12.9 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_15 PF09445.10 PSC68856.1 - 0.062 12.9 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_18 PF12847.7 PSC68856.1 - 0.18 11.7 0.0 0.28 11.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Ion_trans_2 PF07885.16 PSC68857.1 - 6e-12 45.4 8.1 1.6e-11 44.0 7.8 2.1 1 1 0 1 1 1 1 Ion channel Ion_trans PF00520.31 PSC68857.1 - 2.7e-10 39.9 7.5 4.1e-10 39.3 7.5 1.2 1 0 0 1 1 1 1 Ion transport protein IRK PF01007.20 PSC68857.1 - 0.1 12.4 0.5 0.22 11.3 0.5 1.5 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain NMN_transporter PF04973.12 PSC68857.1 - 0.97 9.4 6.0 1.2 9.1 0.1 2.5 2 1 0 2 2 2 0 Nicotinamide mononucleotide transporter CD20 PF04103.15 PSC68858.1 - 0.065 13.3 2.5 0.15 12.2 2.5 1.5 1 0 0 1 1 1 0 CD20-like family Virulence_fact PF13769.6 PSC68858.1 - 0.068 13.4 1.8 0.15 12.3 0.3 2.3 2 0 0 2 2 2 0 Virulence factor DUF2408 PF10303.9 PSC68858.1 - 0.69 10.5 7.8 1 9.9 0.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) PMT_2 PF13231.6 PSC68858.1 - 0.89 9.7 3.4 0.27 11.4 0.2 1.6 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase OmpH PF03938.14 PSC68858.1 - 2.8 8.3 20.1 8.4 6.7 7.6 2.5 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) NusB PF01029.18 PSC68858.1 - 3 8.1 6.6 0.54 10.5 2.8 1.8 2 0 0 2 2 2 0 NusB family CD20 PF04103.15 PSC68859.1 - 0.065 13.3 2.5 0.15 12.2 2.5 1.5 1 0 0 1 1 1 0 CD20-like family Virulence_fact PF13769.6 PSC68859.1 - 0.068 13.4 1.8 0.15 12.3 0.3 2.3 2 0 0 2 2 2 0 Virulence factor DUF2408 PF10303.9 PSC68859.1 - 0.69 10.5 7.3 1.1 9.8 0.5 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) PMT_2 PF13231.6 PSC68859.1 - 0.89 9.8 3.4 0.27 11.5 0.2 1.6 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase UPRTase PF14681.6 PSC68860.1 - 2.1e-55 187.4 0.0 7.3e-28 97.4 0.0 2.2 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase PRK PF00485.18 PSC68860.1 - 1e-45 155.9 0.0 1.5e-45 155.4 0.0 1.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 PSC68860.1 - 3.2e-06 27.7 0.0 5.5e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PSC68860.1 - 4.4e-05 22.8 0.0 8.2e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin CoaE PF01121.20 PSC68860.1 - 0.00019 21.2 0.2 0.024 14.3 0.0 2.2 2 0 0 2 2 2 1 Dephospho-CoA kinase T2SSE PF00437.20 PSC68860.1 - 0.0024 17.0 0.0 0.005 15.9 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_17 PF13207.6 PSC68860.1 - 0.0089 16.5 0.1 0.023 15.1 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PSC68860.1 - 0.036 14.2 0.0 0.076 13.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain Pribosyltran PF00156.27 PSC68860.1 - 0.041 13.4 0.0 0.11 12.0 0.0 1.7 2 0 0 2 2 2 0 Phosphoribosyl transferase domain Flu_C_NS1 PF03506.13 PSC68860.1 - 0.044 13.7 0.2 0.089 12.8 0.2 1.4 1 0 0 1 1 1 0 Influenza C non-structural protein (NS1) Cytidylate_kin PF02224.18 PSC68860.1 - 0.12 12.1 0.6 1 9.0 0.6 2.2 1 1 0 1 1 1 0 Cytidylate kinase Phasin_2 PF09361.10 PSC68860.1 - 0.16 12.2 0.0 0.41 10.9 0.0 1.6 1 0 0 1 1 1 0 Phasin protein Ribonucleas_3_3 PF14622.6 PSC68861.1 - 9e-16 58.2 0.0 1.8e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 PSC68861.1 - 1.8e-13 51.0 0.1 1.4e-12 48.2 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease III domain ADP_ribosyl_GH PF03747.14 PSC68861.1 - 1.9e-12 47.5 6.5 1.9e-12 47.5 6.5 3.5 3 1 0 3 3 3 1 ADP-ribosylglycohydrolase Ribonucleas_3_3 PF14622.6 PSC68862.1 - 9.2e-16 58.2 0.0 1.8e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 PSC68862.1 - 1.9e-13 51.0 0.1 1.4e-12 48.1 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease III domain ADP_ribosyl_GH PF03747.14 PSC68862.1 - 2e-12 47.5 6.5 2e-12 47.5 6.5 3.5 3 1 0 3 3 3 1 ADP-ribosylglycohydrolase Ribonucleas_3_3 PF14622.6 PSC68863.1 - 9.1e-16 58.2 0.0 1.8e-15 57.2 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 PSC68863.1 - 1.8e-13 51.0 0.1 1.4e-12 48.2 0.0 2.3 2 0 0 2 2 2 1 Ribonuclease III domain ADP_ribosyl_GH PF03747.14 PSC68863.1 - 1.9e-12 47.5 6.5 1.9e-12 47.5 6.5 3.5 3 1 0 3 3 3 1 ADP-ribosylglycohydrolase KDZ PF18758.1 PSC68864.1 - 5.7e-15 55.5 2.0 8.3e-15 55.0 2.0 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF2269 PF10027.9 PSC68864.1 - 0.0031 17.6 2.0 0.0065 16.5 1.4 1.8 1 1 1 2 2 2 1 Predicted integral membrane protein (DUF2269) PseudoU_synth_1 PF01416.20 PSC68865.1 - 1.9e-28 99.0 0.0 1.8e-19 70.2 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase Chs7 PF12271.8 PSC68865.1 - 0.097 12.0 0.8 0.15 11.4 0.7 1.3 1 1 0 1 1 1 0 Chitin synthase export chaperone Sclerostin PF05463.11 PSC68865.1 - 0.098 12.4 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Sclerostin (SOST) G3P_acyltransf PF02660.15 PSC68865.1 - 0.44 10.6 5.8 0.73 9.9 5.8 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase EamA PF00892.20 PSC68865.1 - 0.44 10.7 6.9 0.99 9.6 6.9 1.5 1 0 0 1 1 1 0 EamA-like transporter family TRAP_alpha PF03896.16 PSC68865.1 - 0.7 9.0 2.1 15 4.7 0.1 2.1 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit ADK PF00406.22 PSC68866.1 - 1.8e-11 44.4 0.1 7.9e-11 42.3 0.1 2.2 1 1 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 PSC68866.1 - 6.2e-05 23.4 0.0 0.00023 21.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PSC68866.1 - 0.026 15.1 0.0 0.063 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain NT-C2 PF10358.9 PSC68867.1 - 2.9e-06 27.1 0.0 4.6e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins PKcGMP_CC PF16808.5 PSC68867.1 - 0.047 13.5 0.2 0.095 12.6 0.2 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase SlyX PF04102.12 PSC68867.1 - 0.14 12.8 1.6 12 6.6 0.9 3.0 2 0 0 2 2 2 0 SlyX DUF1681 PF07933.14 PSC68868.1 - 3.5e-43 146.9 0.0 4.7e-43 146.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Ribosomal_60s PF00428.19 PSC68868.1 - 4.9 7.8 20.5 4.7 7.9 1.1 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein GHMP_kinases_N PF00288.26 PSC68869.1 - 3.3e-08 33.6 0.5 3.3e-08 33.6 0.5 2.5 2 1 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 PSC68869.1 - 1e-07 32.2 4.1 1.2e-07 32.0 2.7 1.8 2 0 0 2 2 2 1 GHMP kinases C terminal GlcNAc PF11397.8 PSC68870.1 - 1.9e-59 201.9 4.4 1.3e-47 163.0 0.0 3.1 2 1 1 3 3 3 2 Glycosyltransferase (GlcNAc) 2OG-FeII_Oxy_3 PF13640.6 PSC68870.1 - 6.2e-13 49.5 0.3 6.9e-12 46.1 0.3 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 PSC68870.1 - 6.8e-07 29.9 0.0 5.8e-05 23.7 0.0 2.5 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily PC-Esterase PF13839.6 PSC68870.1 - 7.3e-05 22.6 5.1 0.0018 18.1 0.0 3.1 3 0 0 3 3 3 1 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p DDHD PF02862.17 PSC68870.1 - 0.0011 19.2 3.7 0.0019 18.4 3.7 1.3 1 0 0 1 1 1 1 DDHD domain Velvet PF11754.8 PSC68870.1 - 0.0048 16.9 7.6 0.0095 15.9 7.6 1.4 1 0 0 1 1 1 1 Velvet factor Dynamin_N PF00350.23 PSC68870.1 - 0.012 15.7 1.1 0.022 14.8 1.1 1.3 1 0 0 1 1 1 0 Dynamin family EPL1 PF10513.9 PSC68870.1 - 0.014 15.8 8.7 0.023 15.1 8.7 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Band_3_cyto PF07565.13 PSC68870.1 - 0.017 15.0 6.9 0.027 14.3 6.9 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2828 PF11443.8 PSC68870.1 - 0.018 13.2 6.0 0.025 12.7 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DUF4175 PF13779.6 PSC68870.1 - 0.019 12.9 34.7 0.034 12.1 34.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Lin-8 PF03353.15 PSC68870.1 - 0.027 14.0 11.4 0.045 13.3 11.4 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist NARP1 PF12569.8 PSC68870.1 - 0.03 13.3 8.6 0.045 12.7 8.6 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Spt20 PF12090.8 PSC68870.1 - 0.041 13.5 43.6 0.086 12.4 43.6 1.5 1 0 0 1 1 1 0 Spt20 family DUF2126 PF09899.9 PSC68870.1 - 0.069 11.2 5.0 0.1 10.7 5.0 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) CPSF100_C PF13299.6 PSC68870.1 - 0.09 13.0 8.2 0.16 12.1 8.2 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Suf PF05843.14 PSC68870.1 - 0.091 12.7 14.5 0.18 11.8 14.5 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) 2OG-FeII_Oxy_5 PF13759.6 PSC68870.1 - 0.1 13.0 7.9 0.96 9.9 7.9 2.5 1 1 0 1 1 1 0 Putative 2OG-Fe(II) oxygenase Neur_chan_memb PF02932.16 PSC68870.1 - 0.12 12.5 5.9 0.26 11.3 5.9 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Endostatin PF06482.11 PSC68870.1 - 0.14 11.6 9.4 0.23 10.9 9.4 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin MAJIN PF15077.6 PSC68870.1 - 0.22 11.3 3.9 0.41 10.4 3.9 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein CNDH2_M PF16869.5 PSC68870.1 - 0.23 12.1 7.6 0.57 10.9 7.6 1.6 1 0 0 1 1 1 0 PF16858 SpoIIP PF07454.11 PSC68870.1 - 0.24 10.8 16.6 0.37 10.2 16.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) FmiP_Thoc5 PF09766.9 PSC68870.1 - 0.35 10.1 17.1 0.5 9.6 17.1 1.1 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 MID_MedPIWI PF18296.1 PSC68870.1 - 0.46 10.2 12.7 0.75 9.5 12.7 1.2 1 0 0 1 1 1 0 MID domain of medPIWI DUF3464 PF11947.8 PSC68870.1 - 0.85 9.4 13.1 1.7 8.4 13.1 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Otopetrin PF03189.13 PSC68870.1 - 0.86 8.4 2.4 1.2 7.9 2.4 1.1 1 0 0 1 1 1 0 Otopetrin Ndc1_Nup PF09531.10 PSC68870.1 - 0.91 8.1 9.0 1.3 7.6 9.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SID-1_RNA_chan PF13965.6 PSC68870.1 - 1.1 7.6 2.8 1.5 7.1 2.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Zip PF02535.22 PSC68870.1 - 1.1 8.4 3.9 1.7 7.8 3.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CENP-N PF05238.13 PSC68870.1 - 1.3 8.3 10.1 0.34 10.2 7.0 1.5 2 0 0 2 2 1 0 Kinetochore protein CHL4 like Presenilin PF01080.17 PSC68870.1 - 1.5 7.5 18.9 2.4 6.8 18.9 1.2 1 0 0 1 1 1 0 Presenilin VIR_N PF15912.5 PSC68870.1 - 1.6 8.3 7.6 0.16 11.5 2.0 2.0 2 0 0 2 2 2 0 Virilizer, N-terminal Rxt3 PF08642.10 PSC68870.1 - 1.8 9.3 5.4 3.8 8.3 5.4 1.5 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 BAF1_ABF1 PF04684.13 PSC68870.1 - 2.6 7.0 13.7 3.8 6.5 13.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor STAC2_u1 PF16664.5 PSC68870.1 - 2.7 8.4 9.5 5.9 7.4 9.5 1.5 1 0 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 Plasmodium_Vir PF05795.11 PSC68870.1 - 3.6 6.9 4.8 5.2 6.4 4.8 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein eIF-3_zeta PF05091.12 PSC68870.1 - 5.1 5.9 22.4 7.7 5.4 22.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FHIPEP PF00771.20 PSC68870.1 - 5.3 5.4 8.1 8 4.8 8.1 1.1 1 0 0 1 1 1 0 FHIPEP family PAT1 PF09770.9 PSC68870.1 - 7.2 4.7 29.4 11 4.2 29.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CobT PF06213.12 PSC68870.1 - 7.7 5.8 28.3 14 5.0 28.3 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SLC12 PF03522.15 PSC68870.1 - 7.9 5.4 14.6 12 4.8 14.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF913 PF06025.12 PSC68870.1 - 8.4 5.3 11.1 13 4.6 11.1 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF4746 PF15928.5 PSC68870.1 - 8.5 5.7 10.2 14 5.0 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) RR_TM4-6 PF06459.12 PSC68870.1 - 8.6 6.1 17.1 14 5.4 17.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PPL5 PF18168.1 PSC68870.1 - 9.1 5.5 10.9 15 4.7 10.9 1.2 1 0 0 1 1 1 0 Prim-pol family 5 FAM91_C PF14648.6 PSC68870.1 - 9.1 5.0 6.9 16 4.2 6.9 1.3 1 0 0 1 1 1 0 FAM91 C-terminus zf-RING_2 PF13639.6 PSC68871.1 - 2.4e-13 50.2 6.8 4e-13 49.4 6.1 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PSC68871.1 - 1.5e-08 34.3 4.4 4e-08 33.0 4.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PSC68871.1 - 3.3e-08 33.1 0.9 6.3e-08 32.2 0.9 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 PSC68871.1 - 5.7e-08 32.9 10.0 3.7e-07 30.3 10.0 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PSC68871.1 - 2.1e-07 30.7 2.7 4.2e-07 29.7 2.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC68871.1 - 4.1e-07 29.9 2.9 7.5e-07 29.0 2.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PSC68871.1 - 2.8e-06 27.3 0.3 7.2e-06 25.9 0.3 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PSC68871.1 - 4.2e-05 23.3 3.5 4.2e-05 23.3 3.5 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PSC68871.1 - 5.2e-05 23.0 3.6 0.00017 21.4 3.7 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PSC68871.1 - 8e-05 22.6 1.3 8e-05 22.6 1.3 2.0 3 0 0 3 3 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 PSC68871.1 - 0.00047 19.7 9.5 0.0012 18.4 9.5 1.8 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_1 PF14446.6 PSC68871.1 - 0.0092 15.9 3.9 0.15 12.0 1.3 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-C3H2C3 PF17122.5 PSC68871.1 - 0.017 15.2 2.1 0.054 13.5 2.1 1.9 1 1 0 1 1 1 0 Zinc-finger zf-RING_4 PF14570.6 PSC68871.1 - 0.021 14.6 5.3 0.069 13.0 4.9 2.1 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 PSC68871.1 - 0.045 13.9 8.0 9.4 6.5 8.2 3.1 2 1 0 2 2 2 0 FANCL C-terminal domain zf-P11 PF03854.14 PSC68871.1 - 0.22 11.2 4.7 0.6 9.8 4.8 1.8 1 1 0 1 1 1 0 P-11 zinc finger zf-UDP PF14569.6 PSC68871.1 - 0.24 11.5 1.4 0.8 9.9 0.4 2.1 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-RING-like PF08746.11 PSC68871.1 - 0.6 10.5 3.9 1.7 9.0 3.9 1.8 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 PSC68871.1 - 1.3 9.3 9.8 2.2 8.5 9.8 1.4 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 PSC68871.1 - 1.6 8.6 8.6 0.75 9.7 5.5 2.0 2 1 0 2 2 2 0 PHD-finger SBF_like PF13593.6 PSC68872.1 - 1.4e-44 152.7 27.4 1.7e-44 152.4 27.4 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 PSC68872.1 - 1.5e-11 44.3 9.8 1.5e-11 44.3 9.8 2.2 2 0 0 2 2 2 1 Sodium Bile acid symporter family FemAB_like PF04339.12 PSC68873.1 - 0.0002 20.6 0.0 0.00024 20.3 0.0 1.1 1 0 0 1 1 1 1 Peptidogalycan biosysnthesis/recognition Acetyltransf_6 PF13480.7 PSC68873.1 - 0.078 13.1 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain WW PF00397.26 PSC68874.1 - 2.4e-05 24.3 6.0 4.1e-05 23.6 6.0 1.4 1 0 0 1 1 1 1 WW domain Laminin_G_3 PF13385.6 PSC68875.1 - 1.9e-26 93.0 3.1 3.6e-08 33.7 0.6 6.8 4 2 0 4 4 4 4 Concanavalin A-like lectin/glucanases superfamily HhH-GPD PF00730.25 PSC68875.1 - 2.7e-11 43.9 0.0 4.6e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein fn2 PF00040.19 PSC68875.1 - 7.4e-05 22.9 10.2 2.4 8.5 0.0 5.4 5 0 0 5 5 5 3 Fibronectin type II domain Laminin_G_2 PF02210.24 PSC68875.1 - 0.00037 21.1 0.0 0.035 14.7 0.0 2.9 3 0 0 3 3 3 1 Laminin G domain Pentaxin PF00354.17 PSC68875.1 - 0.06 13.0 0.0 16 5.1 0.0 3.1 3 0 0 3 3 3 0 Pentaxin family Apolipoprotein PF01442.18 PSC68876.1 - 3.8e-05 23.7 6.5 0.0081 16.1 1.5 2.3 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain DUF3584 PF12128.8 PSC68876.1 - 6.5e-05 20.7 7.3 0.00094 16.8 1.5 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3584) Baculo_PEP_C PF04513.12 PSC68876.1 - 9.3e-05 22.5 9.7 0.065 13.3 4.7 2.4 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus Mitofilin PF09731.9 PSC68876.1 - 0.00017 20.6 0.8 0.051 12.4 0.1 2.1 2 0 0 2 2 2 2 Mitochondrial inner membrane protein Phasin PF05597.11 PSC68876.1 - 0.0012 18.8 6.3 0.019 14.9 1.4 3.0 2 1 1 3 3 3 1 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF4307 PF14155.6 PSC68876.1 - 0.002 18.0 3.2 0.11 12.4 0.3 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4307) Spectrin PF00435.21 PSC68876.1 - 0.0029 18.1 2.5 0.56 10.7 0.1 3.0 2 1 0 2 2 2 1 Spectrin repeat OmpH PF03938.14 PSC68876.1 - 0.0046 17.3 5.9 0.2 12.0 0.7 2.7 2 1 0 2 2 2 1 Outer membrane protein (OmpH-like) LPD39 PF18858.1 PSC68876.1 - 0.0047 17.0 6.5 0.057 13.5 1.4 2.4 2 0 0 2 2 2 1 Large polyvalent protein associated domain 39 Phage_Mu_Gam PF07352.12 PSC68876.1 - 0.0047 16.8 8.1 0.97 9.3 3.4 2.8 2 1 0 2 2 2 2 Bacteriophage Mu Gam like protein DUF5065 PF16723.5 PSC68876.1 - 0.0054 16.8 4.7 0.71 9.9 0.7 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF5065) Exonuc_VII_L PF02601.15 PSC68876.1 - 0.0085 15.7 2.2 0.88 9.1 0.3 2.1 2 0 0 2 2 2 1 Exonuclease VII, large subunit DUF1690 PF07956.11 PSC68876.1 - 0.0088 16.5 6.1 0.12 12.8 1.8 2.2 2 0 0 2 2 2 1 Protein of Unknown function (DUF1690) NPV_P10 PF05531.12 PSC68876.1 - 0.0099 16.3 17.0 0.3 11.6 1.0 3.3 2 1 2 4 4 4 2 Nucleopolyhedrovirus P10 protein DUF1664 PF07889.12 PSC68876.1 - 0.012 15.7 10.4 0.45 10.6 0.3 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Peptidase_S31 PF05578.12 PSC68876.1 - 0.013 15.0 0.2 2 7.8 0.0 2.3 2 0 0 2 2 2 0 Pestivirus NS3 polyprotein peptidase S31 ZapB PF06005.12 PSC68876.1 - 0.013 15.9 0.8 5 7.6 0.0 3.3 2 1 1 3 3 3 0 Cell division protein ZapB DUF16 PF01519.16 PSC68876.1 - 0.013 15.9 10.2 1.2 9.6 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function DUF16 DUF2203 PF09969.9 PSC68876.1 - 0.018 15.8 2.8 3.7 8.3 0.5 3.2 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) Allexi_40kDa PF05549.11 PSC68876.1 - 0.037 13.5 1.4 0.38 10.2 0.3 2.1 2 0 0 2 2 2 0 Allexivirus 40kDa protein HCV_env PF01539.17 PSC68876.1 - 0.047 13.4 0.1 4.1 7.0 0.0 2.1 2 0 0 2 2 2 0 Hepatitis C virus envelope glycoprotein E1 KxDL PF10241.9 PSC68876.1 - 0.05 13.9 1.6 7.3 6.9 0.1 2.9 2 1 0 2 2 2 0 Uncharacterized conserved protein CopD PF05425.13 PSC68876.1 - 0.052 13.9 12.7 0.68 10.4 2.7 2.5 2 0 0 2 2 2 0 Copper resistance protein D Transglut_core2 PF13369.6 PSC68876.1 - 0.081 12.5 0.3 15 5.1 0.0 2.4 2 0 0 2 2 2 0 Transglutaminase-like superfamily Fzo_mitofusin PF04799.13 PSC68876.1 - 0.096 12.2 3.1 1.5 8.4 0.3 2.4 2 1 0 2 2 2 0 fzo-like conserved region TssO PF17561.2 PSC68876.1 - 0.11 12.6 9.7 1.5 8.9 0.2 2.8 2 1 0 2 2 2 0 Type VI secretion system, TssO DUF1640 PF07798.11 PSC68876.1 - 0.14 12.2 15.5 3.1 7.8 7.1 3.7 2 2 1 3 3 3 0 Protein of unknown function (DUF1640) MtrG PF04210.13 PSC68876.1 - 0.15 12.0 3.8 17 5.3 0.1 3.8 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF4795 PF16043.5 PSC68876.1 - 0.17 11.5 7.8 0.5 9.9 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4795) PIN_8 PF18476.1 PSC68876.1 - 0.2 11.5 5.7 0.7 9.7 1.2 2.2 2 0 0 2 2 2 0 PIN like domain Prominin PF05478.11 PSC68876.1 - 0.36 8.7 2.2 0.9 7.4 0.8 1.9 2 0 0 2 2 2 0 Prominin REF PF05755.12 PSC68876.1 - 0.43 10.4 1.6 1.1 9.1 0.2 2.1 2 1 0 2 2 2 0 Rubber elongation factor protein (REF) BshC PF10079.9 PSC68876.1 - 0.43 9.3 6.5 2.7 6.6 1.2 2.2 2 0 0 2 2 2 0 Bacillithiol biosynthesis BshC LidA_Long_CC PF18641.1 PSC68876.1 - 0.85 9.7 7.7 0.61 10.1 0.9 2.7 2 1 1 3 3 3 0 LidA long coiled-coil domain Syntaxin PF00804.25 PSC68876.1 - 1.1 8.9 7.8 5.4 6.6 0.1 2.6 2 1 1 3 3 3 0 Syntaxin Taxilin PF09728.9 PSC68876.1 - 1.1 8.3 7.3 2 7.5 1.6 2.3 2 0 0 2 2 2 0 Myosin-like coiled-coil protein DUF3482 PF11981.8 PSC68876.1 - 1.3 8.3 11.0 1.4 8.2 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF3482) Muted PF14942.6 PSC68876.1 - 2.3 8.5 7.0 2.9 8.2 2.0 2.3 2 0 0 2 2 2 0 Organelle biogenesis, Muted-like protein Tektin PF03148.14 PSC68876.1 - 3.1 6.5 14.9 2.3 6.9 4.3 2.4 2 1 0 2 2 2 0 Tektin family Snapin_Pallidin PF14712.6 PSC68876.1 - 3.7 8.0 8.5 26 5.3 1.0 3.3 2 2 1 3 3 3 0 Snapin/Pallidin RskA PF10099.9 PSC68876.1 - 4.2 7.6 28.2 0.41 10.9 2.5 2.8 2 1 0 2 2 2 0 Anti-sigma-K factor rskA Fib_alpha PF08702.10 PSC68876.1 - 5.3 7.2 9.7 5.8 7.1 4.4 2.5 2 1 0 2 2 2 0 Fibrinogen alpha/beta chain family PdaC PF13739.6 PSC68876.1 - 5.5 8.0 7.8 12 6.9 2.4 2.4 2 0 0 2 2 2 0 Deacetylase PdaC HrpB2 PF09487.10 PSC68876.1 - 5.7 7.4 6.4 46 4.5 1.1 3.3 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB2) Beta_helix_2 PF18835.1 PSC68876.1 - 7 6.5 9.7 4.3 7.2 0.6 3.1 2 1 1 3 3 3 0 Beta helix repeat of Inulin fructotransferase APG5 PF04106.12 PSC68877.1 - 6.1e-42 143.8 0.0 8.4e-42 143.3 0.0 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 DUF1180 PF06679.12 PSC68877.1 - 6.4 7.2 12.4 12 6.2 12.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SMC_N PF02463.19 PSC68878.1 - 3e-66 223.0 0.3 1e-65 221.2 0.3 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 PSC68878.1 - 5.3e-25 88.0 0.0 2.4e-24 85.9 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 PSC68878.1 - 5.4e-20 72.7 1.0 5.4e-20 72.7 1.0 6.8 2 2 2 4 4 4 1 AAA domain AAA_21 PF13304.6 PSC68878.1 - 2.3e-19 70.3 0.0 1e-10 41.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PSC68878.1 - 2.5e-18 66.9 0.0 9.7e-11 42.0 0.0 2.9 2 1 0 2 2 2 2 AAA ATPase domain ATG16 PF08614.11 PSC68878.1 - 1.1e-05 25.7 4.6 1.1e-05 25.7 4.6 7.6 3 2 4 7 7 7 2 Autophagy protein 16 (ATG16) AAA_29 PF13555.6 PSC68878.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 PSC68878.1 - 6.6 7.2 22.7 0.89 10.1 0.4 5.8 3 3 1 4 4 4 0 ABC transporter Popeye PF04831.13 PSC68880.1 - 4e-08 33.5 2.2 1.4e-07 31.7 2.2 1.7 1 1 0 1 1 1 1 Popeye protein conserved region DUF910 PF06014.11 PSC68882.1 - 0.18 11.9 0.0 0.26 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF910) Popeye PF04831.13 PSC68883.1 - 9.2e-09 35.6 2.9 4e-08 33.5 2.9 1.8 1 1 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 PSC68883.1 - 0.081 13.0 0.0 0.24 11.5 0.0 1.9 2 0 0 2 2 2 0 Cyclic nucleotide-binding domain ThiF PF00899.21 PSC68884.1 - 6e-22 78.2 0.0 2.6e-21 76.1 0.0 1.8 1 1 0 1 1 1 1 ThiF family APG5 PF04106.12 PSC68885.1 - 3.7e-23 82.3 0.0 5.2e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Apg5 KDZ PF18758.1 PSC68887.1 - 1.7e-25 90.0 4.1 3.2e-25 89.1 4.1 1.4 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase CDT1 PF08839.11 PSC68888.1 - 4.1e-14 53.3 0.0 7e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 DNA replication factor CDT1 like CDT1_C PF16679.5 PSC68888.1 - 3.6e-10 40.1 0.2 3.6e-10 40.1 0.2 3.3 3 1 0 3 3 3 1 DNA replication factor Cdt1 C-terminal domain TFIIA PF03153.13 PSC68888.1 - 3.4 7.6 10.7 0.54 10.2 2.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit UCR_14kD PF02271.16 PSC68889.1 - 3.3e-24 84.7 3.3 3.7e-24 84.6 3.3 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit MutS_V PF00488.21 PSC68890.1 - 1.4e-58 198.1 0.0 2.5e-58 197.2 0.0 1.4 1 0 0 1 1 1 1 MutS domain V WD40 PF00400.32 PSC68890.1 - 9e-39 130.8 21.2 3.2e-09 37.2 0.1 6.8 7 0 0 7 7 6 6 WD domain, G-beta repeat MutS_III PF05192.18 PSC68890.1 - 2.4e-28 99.7 0.0 6.7e-28 98.2 0.0 1.8 2 1 0 2 2 2 1 MutS domain III ANAPC4_WD40 PF12894.7 PSC68890.1 - 8.5e-15 54.8 5.7 0.028 14.7 0.0 5.7 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain MutS_IV PF05190.18 PSC68890.1 - 4.3e-06 27.0 0.0 1.3e-05 25.4 0.0 1.8 2 0 0 2 2 2 1 MutS family domain IV Ge1_WD40 PF16529.5 PSC68890.1 - 6.9e-05 22.0 1.3 2.8 6.8 0.0 4.9 1 1 3 4 4 4 1 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PSC68890.1 - 0.0055 16.6 0.0 0.081 12.8 0.0 2.2 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A AAA_27 PF13514.6 PSC68890.1 - 0.009 15.6 0.0 0.033 13.8 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 PSC68890.1 - 0.07 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 PSC68890.1 - 0.085 13.4 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Se-cys_synth_N PF12390.8 PSC68890.1 - 0.092 13.0 0.2 0.092 13.0 0.2 3.0 3 0 0 3 3 2 0 Selenocysteine synthase N terminal Coatomer_WDAD PF04053.14 PSC68890.1 - 0.16 11.0 0.2 3.5 6.6 0.2 2.2 2 0 0 2 2 2 0 Coatomer WD associated region PD40 PF07676.12 PSC68890.1 - 0.19 11.7 0.1 11 6.0 0.0 2.5 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat PDDEXK_6 PF04720.12 PSC68891.1 - 3.7e-15 56.5 0.0 5.4e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 PDDEXK-like family of unknown function DUF5059 PF16502.5 PSC68891.1 - 0.015 14.1 0.4 0.021 13.6 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5059) BCAS2 PF05700.11 PSC68891.1 - 0.05 13.3 0.0 0.086 12.5 0.0 1.3 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 2 (BCAS2) Cyclin PF08613.11 PSC68892.1 - 2.6e-27 96.1 0.0 3.9e-27 95.6 0.0 1.3 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 PSC68892.1 - 0.0038 17.0 0.0 0.006 16.3 0.0 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain UPF1_Zn_bind PF09416.10 PSC68893.1 - 0.079 12.9 0.1 0.2 11.6 0.0 1.5 1 1 0 1 1 1 0 RNA helicase (UPF2 interacting domain) SPOUT_MTase PF02590.17 PSC68894.1 - 2.2e-45 154.4 0.0 2.7e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Predicted SPOUT methyltransferase ETF PF01012.21 PSC68894.1 - 0.0012 18.8 0.3 0.1 12.5 0.0 2.3 2 0 0 2 2 2 2 Electron transfer flavoprotein domain Peptidase_S31 PF05578.12 PSC68895.1 - 0.011 15.2 0.1 0.016 14.7 0.1 1.2 1 0 0 1 1 1 0 Pestivirus NS3 polyprotein peptidase S31 KxDL PF10241.9 PSC68895.1 - 0.013 15.8 0.3 0.28 11.5 0.1 2.2 1 1 1 2 2 2 0 Uncharacterized conserved protein DUF1690 PF07956.11 PSC68895.1 - 0.16 12.4 1.0 0.24 11.8 1.0 1.2 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF1640 PF07798.11 PSC68895.1 - 0.24 11.4 4.8 1 9.4 1.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) DUF1664 PF07889.12 PSC68895.1 - 0.25 11.4 1.4 0.92 9.6 1.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 PSC68895.1 - 0.71 9.2 6.9 0.96 8.7 6.9 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DnaJ PF00226.31 PSC68896.1 - 6.1e-11 42.3 1.4 6.1e-11 42.3 1.4 2.0 2 0 0 2 2 2 1 DnaJ domain NT-C2 PF10358.9 PSC68896.1 - 1.8e-09 37.5 0.0 2.7e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DIL PF01843.19 PSC68896.1 - 3.2e-05 24.2 0.0 0.00011 22.4 0.0 1.9 1 0 0 1 1 1 1 DIL domain MMS19_N PF14500.6 PSC68897.1 - 8.8e-76 254.9 0.0 2.4e-75 253.5 0.0 1.8 1 0 0 1 1 1 1 Dos2-interacting transcription regulator of RNA-Pol-II adh_short PF00106.25 PSC68897.1 - 1.2e-41 142.3 0.0 3.3e-41 140.9 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase Pkinase_Tyr PF07714.17 PSC68897.1 - 4.5e-35 121.2 0.0 8e-29 100.7 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PSC68897.1 - 7e-34 117.4 0.0 5.9e-27 94.7 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain MMS19_C PF12460.8 PSC68897.1 - 9e-24 84.4 0.0 3.6e-23 82.4 0.0 2.0 2 0 0 2 2 2 1 RNAPII transcription regulator C-terminal adh_short_C2 PF13561.6 PSC68897.1 - 2e-23 83.2 0.1 2e-23 83.2 0.1 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase Pkinase_fungal PF17667.1 PSC68897.1 - 1.1e-10 40.9 0.0 1.6e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase HEAT PF02985.22 PSC68897.1 - 0.0059 16.8 2.7 0.11 12.8 0.3 4.5 2 0 0 2 2 2 1 HEAT repeat Polysacc_synt_2 PF02719.15 PSC68897.1 - 0.011 14.9 0.0 0.018 14.2 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.21 PSC68897.1 - 0.13 11.7 0.1 0.36 10.3 0.1 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family CP12 PF02672.15 PSC68898.1 - 2.9e-17 63.2 5.6 5.4e-17 62.3 5.6 1.4 1 0 0 1 1 1 1 CP12 domain KH_1 PF00013.29 PSC68898.1 - 3.3e-17 62.1 0.7 7.5e-17 60.9 0.1 1.9 2 0 0 2 2 2 1 KH domain KH_4 PF13083.6 PSC68898.1 - 6.7e-06 25.9 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 PSC68898.1 - 0.00056 19.7 0.1 0.0014 18.4 0.1 1.7 1 0 0 1 1 1 1 KH domain MOEP19 PF16005.5 PSC68898.1 - 0.014 15.4 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 KH-like RNA-binding domain Trypsin PF00089.26 PSC68899.1 - 7.4e-41 140.4 0.0 1e-40 139.9 0.0 1.1 1 0 0 1 1 1 1 Trypsin AA_kinase PF00696.28 PSC68901.1 - 7.9e-23 81.3 7.6 1.1e-13 51.4 0.0 2.8 1 1 1 2 2 2 2 Amino acid kinase family PEMT PF04191.13 PSC68901.1 - 8.9e-12 45.3 2.2 1.9e-11 44.3 2.2 1.5 1 0 0 1 1 1 1 Phospholipid methyltransferase ICMT PF04140.14 PSC68901.1 - 0.036 14.5 1.0 0.2 12.1 0.1 2.2 1 1 1 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Trypsin PF00089.26 PSC68903.1 - 1.6e-18 67.4 0.0 1.9e-18 67.1 0.0 1.1 1 0 0 1 1 1 1 Trypsin AMP-binding PF00501.28 PSC68906.1 - 2e-76 257.3 0.0 4.9e-76 256.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme PNP_UDP_1 PF01048.20 PSC68906.1 - 1.3e-21 76.9 0.5 3.5e-21 75.5 0.0 2.0 2 0 0 2 2 2 1 Phosphorylase superfamily Abhydrolase_2 PF02230.16 PSC68906.1 - 2.2e-16 60.3 0.0 6.5e-16 58.8 0.0 1.7 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase AMP-binding_C PF13193.6 PSC68906.1 - 2.2e-15 57.4 0.1 8.5e-15 55.5 0.1 2.1 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain FSH1 PF03959.13 PSC68906.1 - 1.2e-05 25.1 0.0 1.9e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) TPR_1 PF00515.28 PSC68906.1 - 2.6e-05 23.8 11.6 0.0076 16.0 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat Hydrolase_4 PF12146.8 PSC68906.1 - 8.8e-05 21.9 5.4 0.11 11.8 0.1 3.6 2 1 1 3 3 3 2 Serine aminopeptidase, S33 TPR_2 PF07719.17 PSC68906.1 - 0.00052 19.9 18.5 0.056 13.6 1.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat Thioesterase PF00975.20 PSC68906.1 - 0.00068 19.8 1.2 0.0017 18.5 1.2 1.6 1 0 0 1 1 1 1 Thioesterase domain DLH PF01738.18 PSC68906.1 - 0.0007 19.2 0.0 0.0015 18.1 0.0 1.5 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 PSC68906.1 - 0.00093 19.1 0.4 0.00093 19.1 0.4 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 PSC68906.1 - 0.0025 17.5 0.0 0.0053 16.4 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Fis1_TPR_C PF14853.6 PSC68906.1 - 0.0037 17.3 0.7 0.034 14.2 0.1 2.4 1 1 1 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 PSC68906.1 - 0.0041 16.8 0.6 0.94 9.2 0.0 2.6 2 0 0 2 2 2 1 TPR repeat Esterase PF00756.20 PSC68906.1 - 0.0043 16.7 0.1 0.0082 15.8 0.1 1.4 1 0 0 1 1 1 1 Putative esterase Lipase PF00151.19 PSC68906.1 - 0.058 12.7 0.0 0.093 12.0 0.0 1.2 1 0 0 1 1 1 0 Lipase PGAP1 PF07819.13 PSC68906.1 - 0.058 13.1 0.0 0.097 12.4 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF3856 PF12968.7 PSC68906.1 - 0.24 11.4 3.0 2.3 8.3 3.0 2.3 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) RTA1 PF04479.13 PSC68907.1 - 2.8e-32 112.0 9.7 2.8e-32 112.0 9.7 1.6 1 1 1 2 2 2 1 RTA1 like protein DUF3392 PF11872.8 PSC68907.1 - 0.085 13.1 0.5 0.085 13.1 0.5 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3392) Ribosomal_L24e PF01246.20 PSC68908.1 - 4.3e-07 30.1 0.7 4.3e-07 30.1 0.7 1.8 2 0 0 2 2 2 1 Ribosomal protein L24e TetR_C_11 PF16859.5 PSC68908.1 - 0.14 12.5 2.2 0.19 12.1 2.2 1.3 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain Ebp2 PF05890.12 PSC68908.1 - 0.21 11.1 14.3 0.24 10.9 14.1 1.3 1 1 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 TSP_NTD PF17804.1 PSC68908.1 - 2.6 8.2 8.9 2.9 8.1 8.9 1.1 1 0 0 1 1 1 0 Tail specific protease N-terminal domain AAA_23 PF13476.6 PSC68908.1 - 8.6 6.8 8.6 11 6.5 8.6 1.1 1 0 0 1 1 1 0 AAA domain DUF1138 PF06592.13 PSC68909.1 - 2.2e-10 40.5 0.1 3.1e-10 40.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1138) DNA_topoisoIV PF00521.20 PSC68910.1 - 6.7e-133 443.7 0.0 2.2e-132 442.0 0.0 1.8 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 PSC68910.1 - 2.3e-50 170.2 2.0 2.3e-50 170.2 2.0 2.1 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 PSC68910.1 - 1.6e-22 79.8 0.0 4.1e-22 78.5 0.0 1.6 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 PSC68910.1 - 3.7e-11 43.5 0.0 7.8e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 PSC68910.1 - 5e-07 29.9 0.0 1.5e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 Toprim domain PfkB PF00294.24 PSC68911.1 - 1.7e-55 188.5 2.3 2.7e-55 187.8 2.3 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase AP_endonuc_2 PF01261.24 PSC68911.1 - 5.2e-18 65.3 0.6 1.4e-17 63.9 0.1 1.9 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel Phos_pyr_kin PF08543.12 PSC68911.1 - 0.00021 20.8 0.0 0.00042 19.8 0.0 1.4 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase VCX_VCY PF15231.6 PSC68911.1 - 8.2 7.1 7.3 19 5.9 7.3 1.6 1 0 0 1 1 1 0 Variable charge X/Y family PPR_2 PF13041.6 PSC68912.1 - 2e-67 223.2 0.0 2.6e-13 49.9 0.0 9.6 5 2 4 9 9 9 9 PPR repeat family PPR PF01535.20 PSC68912.1 - 8.6e-64 207.5 0.3 3e-07 30.2 0.0 11.3 12 0 0 12 12 12 8 PPR repeat PPR_1 PF12854.7 PSC68912.1 - 2.8e-51 170.9 0.0 2.4e-06 27.1 0.0 9.3 9 0 0 9 9 9 8 PPR repeat PPR_3 PF13812.6 PSC68912.1 - 3.2e-47 158.4 0.0 1.3e-11 44.4 0.0 8.2 3 2 4 8 8 8 8 Pentatricopeptide repeat domain PPR_long PF17177.4 PSC68912.1 - 2.8e-22 79.1 0.0 1.9e-11 43.7 0.0 4.4 2 1 2 4 4 4 4 Pentacotripeptide-repeat region of PRORP TPR_7 PF13176.6 PSC68912.1 - 8.9e-09 34.8 8.2 0.46 10.6 0.1 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 PSC68912.1 - 3.1e-05 23.6 0.7 13 5.8 0.1 6.0 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_2 PF07719.17 PSC68912.1 - 7e-05 22.6 7.0 9.7 6.6 0.2 7.3 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_14 PF13428.6 PSC68912.1 - 0.0002 21.9 39.8 2 9.5 0.0 10.6 9 3 2 11 11 10 3 Tetratricopeptide repeat TPR_6 PF13174.6 PSC68912.1 - 0.015 15.9 6.7 26 5.7 0.0 6.1 6 1 0 6 6 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 PSC68912.1 - 0.056 13.7 10.8 2.9 8.2 0.1 6.5 7 1 1 8 8 8 0 Tetratricopeptide repeat DUF2380 PF09533.10 PSC68912.1 - 4.9 6.7 16.8 8 6.0 0.1 5.8 4 2 2 6 6 5 0 Predicted lipoprotein of unknown function (DUF2380) Ank_2 PF12796.7 PSC68913.1 - 1e-18 67.7 0.0 5.4e-11 42.9 0.0 3.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC68913.1 - 4.2e-17 62.3 0.1 1.8e-10 41.2 0.1 4.2 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC68913.1 - 4.1e-16 58.8 0.7 1.3e-11 44.5 0.2 4.0 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Methyltransf_11 PF08241.12 PSC68913.1 - 3.5e-15 56.4 0.0 9.1e-13 48.7 0.0 2.5 1 1 0 1 1 1 1 Methyltransferase domain Ank PF00023.30 PSC68913.1 - 6e-15 54.9 1.0 3.8e-06 27.1 0.3 4.9 4 0 0 4 4 4 3 Ankyrin repeat Methyltransf_25 PF13649.6 PSC68913.1 - 3e-13 50.3 0.0 4.1e-06 27.4 0.0 2.5 1 1 1 2 2 2 2 Methyltransferase domain Ank_3 PF13606.6 PSC68913.1 - 3.8e-10 39.1 0.7 0.016 15.7 0.1 5.0 5 0 0 5 5 5 2 Ankyrin repeat Methyltransf_12 PF08242.12 PSC68913.1 - 8.4e-09 36.1 0.0 3.2e-08 34.2 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC68913.1 - 3.4e-08 33.5 0.0 5.7e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC68913.1 - 0.00011 22.0 0.0 0.0032 17.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 PSC68913.1 - 0.00049 19.4 0.0 0.14 11.4 0.0 2.2 1 1 1 2 2 2 2 O-methyltransferase domain MTS PF05175.14 PSC68913.1 - 0.00052 19.6 0.0 0.34 10.5 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase small domain Med6 PF04934.14 PSC68914.1 - 5.5e-30 103.9 0.0 7.5e-30 103.4 0.0 1.1 1 0 0 1 1 1 1 MED6 mediator sub complex component Prenyltransf PF01255.19 PSC68915.1 - 3.5e-70 236.0 0.4 7.9e-70 234.9 0.0 1.7 2 0 0 2 2 2 1 Putative undecaprenyl diphosphate synthase FAST_1 PF06743.15 PSC68916.1 - 4.7e-07 29.7 0.0 0.11 12.5 0.0 4.1 3 1 2 5 5 5 4 FAST kinase-like protein, subdomain 1 DUF4926 PF16277.5 PSC68916.1 - 0.035 13.5 0.0 0.09 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4926) XG_FTase PF03254.13 PSC68917.1 - 0.015 13.9 0.1 0.22 10.1 0.1 2.3 2 1 0 2 2 2 0 Xyloglucan fucosyltransferase GATase_2 PF00310.21 PSC68918.1 - 2.3e-179 596.5 0.0 3.2e-179 596.0 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 PSC68918.1 - 1.2e-152 508.4 0.7 2.3e-152 507.4 0.7 1.5 1 0 0 1 1 1 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 PSC68918.1 - 6.7e-107 357.1 0.0 4.3e-106 354.5 0.0 2.0 2 0 0 2 2 2 1 Glutamate synthase central domain GXGXG PF01493.19 PSC68918.1 - 8.7e-80 266.8 2.6 1.7e-79 265.9 2.6 1.4 1 0 0 1 1 1 1 GXGXG motif Pkinase PF00069.25 PSC68918.1 - 1.4e-60 204.9 0.0 2.1e-60 204.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain FAD-oxidase_C PF02913.19 PSC68918.1 - 2.6e-44 151.8 0.0 6e-44 150.5 0.0 1.6 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 PSC68918.1 - 6.1e-28 97.3 0.2 2e-27 95.6 0.2 2.0 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 PSC68918.1 - 2.4e-26 92.7 0.0 1.3e-25 90.3 0.1 2.2 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_20 PF14691.6 PSC68918.1 - 1e-24 86.4 5.5 1.3e-20 73.3 0.0 3.5 3 0 0 3 3 3 2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pkinase_Tyr PF07714.17 PSC68918.1 - 1.4e-23 83.5 0.0 2.3e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ADH_zinc_N PF00107.26 PSC68918.1 - 8.8e-12 45.1 0.5 5.1e-11 42.7 0.5 2.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase NAD_binding_8 PF13450.6 PSC68918.1 - 3.7e-09 36.7 0.1 2.4e-08 34.1 0.0 2.5 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Fer4_8 PF13183.6 PSC68918.1 - 6.9e-09 36.0 8.2 1e-08 35.5 2.2 3.3 3 0 0 3 3 3 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 PSC68918.1 - 1.1e-07 32.4 2.8 1.1e-07 32.4 2.8 3.3 3 0 0 3 3 3 1 4Fe-4S dicluster domain Pyr_redox PF00070.27 PSC68918.1 - 2.1e-07 31.4 1.8 2.8e-05 24.6 0.2 3.0 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PSC68918.1 - 1.1e-06 28.5 1.8 0.0019 17.8 0.4 2.7 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 PSC68918.1 - 1.3e-06 28.1 0.1 2.8e-06 27.0 0.1 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 PSC68918.1 - 1.6e-06 27.7 0.0 3e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 PSC68918.1 - 5.2e-06 25.4 0.5 1.2e-05 24.3 0.5 1.6 1 0 0 1 1 1 1 HI0933-like protein Fer4_17 PF13534.6 PSC68918.1 - 6.3e-06 26.6 3.7 6.3e-06 26.6 3.7 3.3 3 0 0 3 3 3 1 4Fe-4S dicluster domain ADH_zinc_N_2 PF13602.6 PSC68918.1 - 8e-06 26.9 0.0 4.2e-05 24.6 0.0 2.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAD_binding_2 PF00890.24 PSC68918.1 - 1.2e-05 24.6 0.6 7.1e-05 22.1 0.2 2.3 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 PSC68918.1 - 3.9e-05 23.1 1.5 0.0019 17.6 0.1 2.6 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_16 PF13484.6 PSC68918.1 - 0.00068 20.5 3.4 0.0023 18.8 3.4 2.0 1 0 0 1 1 1 1 4Fe-4S double cluster binding domain NAD_binding_7 PF13241.6 PSC68918.1 - 0.0011 19.4 0.6 0.34 11.4 0.1 2.6 2 0 0 2 2 2 1 Putative NAD(P)-binding ADH_N PF08240.12 PSC68918.1 - 0.0012 18.7 0.0 0.021 14.7 0.0 3.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain GIDA PF01134.22 PSC68918.1 - 0.0022 17.2 1.0 0.0022 17.2 1.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A FAD_binding_3 PF01494.19 PSC68918.1 - 0.0027 17.0 0.1 0.0051 16.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 PSC68918.1 - 0.0059 15.9 4.0 0.13 11.6 0.1 3.0 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain FMO-like PF00743.19 PSC68918.1 - 0.0097 14.4 0.1 0.11 10.9 0.0 2.4 3 0 0 3 3 3 1 Flavin-binding monooxygenase-like Thi4 PF01946.17 PSC68918.1 - 0.016 14.5 0.2 0.038 13.2 0.2 1.6 1 0 0 1 1 1 0 Thi4 family Fer4_10 PF13237.6 PSC68918.1 - 0.065 13.4 11.4 0.0086 16.2 3.1 3.4 3 1 0 3 3 3 0 4Fe-4S dicluster domain Lycopene_cycl PF05834.12 PSC68918.1 - 0.11 11.6 0.2 0.24 10.4 0.1 1.6 2 0 0 2 2 1 0 Lycopene cyclase protein MRF_C1 PF13887.6 PSC68918.1 - 0.11 11.6 0.0 0.33 10.2 0.0 1.8 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 F420_oxidored PF03807.17 PSC68918.1 - 0.11 13.0 0.0 3.4 8.3 0.1 2.9 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 PSC68918.1 - 0.19 11.1 0.1 2.4 7.5 0.1 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 PSC68918.1 - 0.28 11.3 2.3 6.3 6.8 0.2 2.5 2 0 0 2 2 2 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Fer4_4 PF12800.7 PSC68918.1 - 0.99 10.1 10.6 0.033 14.7 1.9 3.0 2 0 0 2 2 1 0 4Fe-4S binding domain Fer4 PF00037.27 PSC68918.1 - 2.5 8.1 16.3 0.079 12.8 2.2 3.2 3 0 0 3 3 2 0 4Fe-4S binding domain Ribosomal_L7Ae PF01248.26 PSC68919.1 - 1.5e-26 92.0 0.8 1.8e-26 91.7 0.8 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family LCM PF04072.14 PSC68920.1 - 2.6e-15 56.9 0.0 3.8e-15 56.3 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase RCC_reductase PF06405.11 PSC68920.1 - 0.00043 19.5 0.0 0.00089 18.5 0.0 1.5 1 0 0 1 1 1 1 Red chlorophyll catabolite reductase (RCC reductase) HTH_8 PF02954.19 PSC68920.1 - 0.27 11.1 1.8 10 6.0 0.0 2.9 3 0 0 3 3 3 0 Bacterial regulatory protein, Fis family PIN_4 PF13638.6 PSC68922.1 - 5.7e-14 52.5 0.0 1.9e-13 50.8 0.0 2.0 1 0 0 1 1 1 1 PIN domain Mito_carr PF00153.27 PSC68923.1 - 1.5e-56 188.3 1.9 5.7e-19 67.8 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Rieske PF00355.26 PSC68924.1 - 3.6e-15 55.7 0.8 7e-15 54.8 0.0 1.9 2 0 0 2 2 2 1 Rieske [2Fe-2S] domain PaO PF08417.12 PSC68924.1 - 8.3e-11 41.9 0.0 1.4e-10 41.2 0.0 1.3 1 0 0 1 1 1 1 Pheophorbide a oxygenase Aminotran_1_2 PF00155.21 PSC68925.1 - 2.4e-38 132.2 0.0 3e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II NADH_oxidored PF08040.11 PSC68925.1 - 0.14 11.9 0.0 13 5.5 0.0 2.5 2 0 0 2 2 2 0 MNLL subunit SET PF00856.28 PSC68926.1 - 6.1e-13 49.5 0.1 1.6e-11 44.9 0.0 3.0 2 1 0 2 2 2 1 SET domain preSET_CXC PF18264.1 PSC68926.1 - 1.5e-06 28.5 14.0 1.5e-06 28.5 14.0 3.3 3 1 0 3 3 3 1 CXC domain Myb_DNA-binding PF00249.31 PSC68926.1 - 0.0035 17.5 0.2 0.014 15.5 0.2 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain ETF PF01012.21 PSC68927.1 - 1.1e-43 149.3 8.0 1.1e-43 149.3 8.0 1.8 2 0 0 2 2 2 1 Electron transfer flavoprotein domain BTB PF00651.31 PSC68927.1 - 2.4e-06 27.7 0.0 4.4e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain IBR PF01485.21 PSC68928.1 - 1.7e-15 57.0 42.2 1.6e-11 44.3 3.2 5.0 3 1 2 5 5 5 2 IBR domain, a half RING-finger domain TFIIA PF03153.13 PSC68928.1 - 0.00057 20.0 20.8 0.00066 19.8 20.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-C3HC4 PF00097.25 PSC68928.1 - 0.0019 18.1 0.6 0.0019 18.1 0.6 3.8 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) C1_4 PF07975.12 PSC68928.1 - 0.026 14.7 1.9 0.026 14.7 1.9 4.4 4 1 0 4 4 3 0 TFIIH C1-like domain Suf PF05843.14 PSC68928.1 - 0.14 12.1 6.4 0.18 11.8 6.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 PSC68928.1 - 0.95 9.5 5.0 1.2 9.1 5.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Asparaginase_2 PF01112.18 PSC68928.1 - 0.99 8.4 7.7 1.5 7.7 7.7 1.2 1 0 0 1 1 1 0 Asparaginase Pex14_N PF04695.13 PSC68928.1 - 1.6 9.3 18.6 2.7 8.6 18.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF3_subunit PF08597.10 PSC68928.1 - 2.4 8.0 8.4 3.3 7.6 8.4 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit TERB2 PF15101.6 PSC68928.1 - 3.9 7.5 14.5 5.8 6.9 14.5 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Spt20 PF12090.8 PSC68928.1 - 5.5 6.5 31.0 9.2 5.8 31.0 1.4 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 PSC68928.1 - 5.8 5.6 12.0 7.7 5.2 12.0 1.1 1 0 0 1 1 1 0 Presenilin Ribosomal_60s PF00428.19 PSC68928.1 - 7.1 7.3 9.6 16 6.2 9.6 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein DNA_ligase_ZBD PF03119.16 PSC68928.1 - 8.1 6.6 21.0 0.42 10.7 0.6 3.7 3 1 0 3 3 3 0 NAD-dependent DNA ligase C4 zinc finger domain Activator_LAG-3 PF11498.8 PSC68928.1 - 8.5 5.2 38.5 17 4.2 38.5 1.5 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Hist_deacetyl PF00850.19 PSC68929.1 - 1.3e-84 284.3 0.1 1.8e-84 283.8 0.1 1.2 1 0 0 1 1 1 1 Histone deacetylase domain DUF3022 PF11226.8 PSC68929.1 - 2.2 8.8 4.8 12 6.4 2.3 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3022) RraA-like PF03737.15 PSC68930.1 - 5.1e-43 146.8 0.2 2.4e-42 144.6 0.2 2.0 2 0 0 2 2 2 1 Aldolase/RraA DUF3455 PF11937.8 PSC68930.1 - 1.1e-05 25.8 0.0 2e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3455) PAN_4 PF14295.6 PSC68930.1 - 0.00043 20.1 2.8 0.0012 18.7 2.8 1.7 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 PSC68930.1 - 0.039 13.9 0.2 0.082 12.9 0.2 1.5 1 0 0 1 1 1 0 PAN domain G-patch PF01585.23 PSC68931.1 - 4.9e-12 45.5 2.5 4.9e-12 45.5 2.5 2.1 2 0 0 2 2 2 1 G-patch domain DUF563 PF04577.14 PSC68931.1 - 3.1e-07 30.8 0.0 6.8e-07 29.6 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF563) RRM_1 PF00076.22 PSC68931.1 - 3.3e-05 23.6 0.1 8.9e-05 22.2 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Complex1_LYR PF05347.15 PSC68932.1 - 3.9e-05 23.6 1.4 6e-05 23.0 1.4 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF5631 PF18645.1 PSC68933.1 - 0.026 14.9 8.1 0.96 9.9 0.5 3.2 2 1 0 2 2 2 0 Family of unknown function (DUF5631) Filament PF00038.21 PSC68933.1 - 0.1 12.1 29.5 0.041 13.5 9.7 3.1 1 1 1 3 3 3 0 Intermediate filament protein Adaptin_binding PF10199.9 PSC68933.1 - 0.38 11.4 12.1 5.3 7.7 12.1 2.9 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 BRE1 PF08647.11 PSC68933.1 - 2.7 8.1 27.6 0.064 13.3 5.8 3.8 3 1 0 3 3 3 0 BRE1 E3 ubiquitin ligase LPMO_10 PF03067.15 PSC68933.1 - 4 8.0 11.9 8.7 6.9 1.1 2.7 1 1 0 2 2 2 0 Lytic polysaccharide mono-oxygenase, cellulose-degrading bZIP_1 PF00170.21 PSC68933.1 - 9.6 6.4 12.7 3.6 7.8 1.3 3.5 3 0 0 3 3 3 0 bZIP transcription factor LCM PF04072.14 PSC68934.1 - 3e-10 40.3 0.0 3e-10 40.3 0.0 3.4 3 2 0 3 3 1 1 Leucine carboxyl methyltransferase CDC45 PF02724.14 PSC68934.1 - 3.2e-09 35.7 0.5 4.1e-09 35.3 0.5 1.1 1 0 0 1 1 1 1 CDC45-like protein NAD_binding_8 PF13450.6 PSC68934.1 - 1.2e-08 35.1 0.2 3.6e-08 33.5 0.2 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PSC68934.1 - 6.7e-07 29.2 1.2 2.3e-06 27.4 0.4 2.0 1 1 1 2 2 2 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 PSC68934.1 - 1.2e-05 24.9 0.4 1.2e-05 24.9 0.4 2.2 2 0 0 2 2 1 1 FAD dependent oxidoreductase TFIIA PF03153.13 PSC68934.1 - 1.7e-05 25.1 48.9 3.7e-05 23.9 48.9 1.5 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Pyr_redox PF00070.27 PSC68934.1 - 2.9e-05 24.5 0.0 8.1e-05 23.1 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PSC68934.1 - 3.4e-05 23.2 0.9 6.7e-05 22.3 0.9 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DDHD PF02862.17 PSC68934.1 - 8.3e-05 22.9 8.6 0.00014 22.1 8.6 1.4 1 0 0 1 1 1 1 DDHD domain HI0933_like PF03486.14 PSC68934.1 - 0.00019 20.2 0.1 0.00019 20.2 0.1 2.1 2 0 0 2 2 1 1 HI0933-like protein FAD_binding_2 PF00890.24 PSC68934.1 - 0.00024 20.3 0.3 0.00024 20.3 0.3 2.2 2 0 0 2 2 1 1 FAD binding domain NPR3 PF03666.13 PSC68934.1 - 0.00031 19.7 14.9 0.00043 19.2 14.9 1.1 1 0 0 1 1 1 1 Nitrogen Permease regulator of amino acid transport activity 3 Zip PF02535.22 PSC68934.1 - 0.00068 18.9 2.8 0.00068 18.9 2.8 1.6 2 0 0 2 2 1 1 ZIP Zinc transporter Thi4 PF01946.17 PSC68934.1 - 0.001 18.3 0.3 0.0024 17.2 0.1 1.6 2 0 0 2 2 1 1 Thi4 family Methyltransf_32 PF13679.6 PSC68934.1 - 0.0019 18.2 14.5 0.36 10.8 13.3 3.4 3 0 0 3 3 3 1 Methyltransferase domain SLC12 PF03522.15 PSC68934.1 - 0.0019 17.3 20.0 0.0029 16.7 20.0 1.2 1 0 0 1 1 1 1 Solute carrier family 12 DUF1391 PF07151.12 PSC68934.1 - 0.0023 17.7 0.0 0.0044 16.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1391) Velvet PF11754.8 PSC68934.1 - 0.0073 16.3 16.5 0.013 15.5 16.5 1.4 1 0 0 1 1 1 1 Velvet factor GIDA PF01134.22 PSC68934.1 - 0.008 15.3 0.2 0.008 15.3 0.2 2.2 2 0 0 2 2 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 PSC68934.1 - 0.0096 15.2 0.0 0.0096 15.2 0.0 1.6 2 0 0 2 2 1 1 Flavin containing amine oxidoreductase SRP-alpha_N PF04086.13 PSC68934.1 - 0.015 15.2 21.3 0.023 14.6 21.3 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF913 PF06025.12 PSC68934.1 - 0.018 14.0 11.0 0.028 13.4 11.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ThiF PF00899.21 PSC68934.1 - 0.025 13.9 0.0 0.81 9.0 2.8 1.9 2 1 0 2 2 2 0 ThiF family DUF908 PF06012.12 PSC68934.1 - 0.027 13.9 14.7 0.041 13.3 14.7 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) ASC PF00858.24 PSC68934.1 - 0.035 13.1 12.2 0.049 12.6 12.2 1.1 1 0 0 1 1 1 0 Amiloride-sensitive sodium channel TCP PF03634.13 PSC68934.1 - 0.041 14.4 20.1 0.066 13.8 20.1 1.3 1 0 0 1 1 1 0 TCP family transcription factor SAPS PF04499.15 PSC68934.1 - 0.063 12.1 14.5 0.089 11.6 14.5 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pkinase_fungal PF17667.1 PSC68934.1 - 0.077 11.8 8.0 0.11 11.3 8.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Otopetrin PF03189.13 PSC68934.1 - 0.082 11.7 9.3 0.11 11.3 9.3 1.1 1 0 0 1 1 1 0 Otopetrin RR_TM4-6 PF06459.12 PSC68934.1 - 0.094 12.5 25.3 0.15 11.9 25.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 PSC68934.1 - 0.11 11.9 23.9 0.19 11.2 23.9 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CPSF100_C PF13299.6 PSC68934.1 - 0.12 12.6 15.1 0.29 11.3 15.1 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal NAD_binding_7 PF13241.6 PSC68934.1 - 0.13 12.8 0.0 0.3 11.6 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding Vac7 PF12751.7 PSC68934.1 - 0.13 11.7 8.3 0.19 11.1 8.3 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 eIF-3_zeta PF05091.12 PSC68934.1 - 0.15 11.0 37.0 0.21 10.5 37.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hamartin PF04388.12 PSC68934.1 - 0.15 10.7 18.5 0.22 10.1 18.5 1.2 1 0 0 1 1 1 0 Hamartin protein FAM60A PF15396.6 PSC68934.1 - 0.16 11.9 17.9 0.27 11.2 17.9 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Endostatin PF06482.11 PSC68934.1 - 0.17 11.3 21.7 0.26 10.7 21.7 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin GAGA_bind PF06217.12 PSC68934.1 - 0.19 12.0 16.8 0.3 11.3 16.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF2151 PF10221.9 PSC68934.1 - 0.24 10.0 10.9 0.33 9.5 10.9 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Pex14_N PF04695.13 PSC68934.1 - 0.25 12.0 40.9 0.066 13.9 37.1 2.0 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SID-1_RNA_chan PF13965.6 PSC68934.1 - 0.25 9.7 9.2 0.34 9.3 9.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 PSC68934.1 - 0.26 10.0 33.3 0.4 9.4 33.3 1.2 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 PSC68934.1 - 0.29 9.4 45.5 0.4 8.9 45.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAD_binding_3 PF01494.19 PSC68934.1 - 0.42 9.8 23.3 26 3.9 23.8 2.9 2 1 0 2 2 2 0 FAD binding domain Kei1 PF08552.11 PSC68934.1 - 0.44 10.4 14.1 0.94 9.3 14.1 1.5 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 PIP5K PF01504.18 PSC68934.1 - 0.79 8.9 17.4 1.2 8.2 17.4 1.3 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase CLN3 PF02487.17 PSC68934.1 - 0.79 8.7 18.0 1.2 8.1 18.0 1.1 1 0 0 1 1 1 0 CLN3 protein BORG_CEP PF14957.6 PSC68934.1 - 1.1 10.5 15.0 2.2 9.5 15.0 1.5 1 0 0 1 1 1 0 Cdc42 effector Tim54 PF11711.8 PSC68934.1 - 1.1 8.0 21.5 5.2 5.8 22.7 1.5 2 0 0 2 2 1 0 Inner membrane protein import complex subunit Tim54 AAA_11 PF13086.6 PSC68934.1 - 1.2 8.9 23.1 1.8 8.3 23.1 1.2 1 0 0 1 1 1 0 AAA domain DUF3807 PF12720.7 PSC68934.1 - 1.2 9.3 35.4 1.9 8.7 35.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Lin-8 PF03353.15 PSC68934.1 - 1.4 8.4 31.2 2.1 7.8 31.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ctr PF04145.15 PSC68934.1 - 1.4 9.5 14.4 3.5 8.3 14.4 1.7 1 0 0 1 1 1 0 Ctr copper transporter family Serinc PF03348.15 PSC68934.1 - 1.4 7.7 13.7 2.1 7.2 13.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4045 PF13254.6 PSC68934.1 - 1.5 8.4 24.1 1.9 8.1 21.8 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) DUF2201_N PF13203.6 PSC68934.1 - 1.6 8.2 18.3 3.3 7.2 18.3 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain SART-1 PF03343.13 PSC68934.1 - 1.9 6.9 30.5 2.6 6.5 30.5 1.1 1 0 0 1 1 1 0 SART-1 family NARP1 PF12569.8 PSC68934.1 - 2.5 6.9 24.8 3.6 6.4 24.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Neur_chan_memb PF02932.16 PSC68934.1 - 2.6 8.1 21.4 4.7 7.2 21.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2370 PF10176.9 PSC68934.1 - 2.8 7.5 13.8 4.9 6.7 13.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Exonuc_VII_L PF02601.15 PSC68934.1 - 2.9 7.4 24.4 4.4 6.8 24.4 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Peroxin-3 PF04882.12 PSC68934.1 - 3.1 6.7 26.5 4.6 6.1 26.5 1.2 1 0 0 1 1 1 0 Peroxin-3 Ndc1_Nup PF09531.10 PSC68934.1 - 3.2 6.3 20.1 4.6 5.8 20.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Peptidase_S15 PF02129.18 PSC68934.1 - 3.2 7.3 16.7 7.2 6.1 16.7 1.6 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) CCDC53 PF10152.9 PSC68934.1 - 4 7.8 30.1 0.79 10.1 25.7 2.0 2 0 0 2 2 1 0 Subunit CCDC53 of WASH complex BAF1_ABF1 PF04684.13 PSC68934.1 - 4.1 6.4 23.5 7 5.6 23.5 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor WTX PF09422.10 PSC68934.1 - 4.7 6.2 16.8 7.5 5.5 16.8 1.2 1 0 0 1 1 1 0 WTX protein Het-C PF07217.11 PSC68934.1 - 5.5 5.4 13.5 8.3 4.8 13.5 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C CCSAP PF15748.5 PSC68934.1 - 5.7 7.0 31.7 9.6 6.3 31.7 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated AF-4 PF05110.13 PSC68934.1 - 6 4.8 29.4 8.4 4.3 29.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein RP-C_C PF11800.8 PSC68934.1 - 6.3 6.8 23.4 0.25 11.4 16.9 1.8 2 0 0 2 2 1 0 Replication protein C C-terminal region GPCR_chapero_1 PF11904.8 PSC68934.1 - 7.5 5.9 16.3 11 5.3 16.3 1.1 1 0 0 1 1 1 0 GPCR-chaperone Membralin PF09746.9 PSC68934.1 - 7.8 5.4 16.9 11 4.9 16.9 1.1 1 0 0 1 1 1 0 Tumour-associated protein eIF3_subunit PF08597.10 PSC68934.1 - 7.8 6.3 26.4 12 5.7 26.4 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit 3HCDH_N PF02737.18 PSC68934.1 - 8.8 6.2 14.6 1.6 8.6 0.0 3.1 2 1 1 3 3 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF2828 PF11443.8 PSC68934.1 - 9.2 4.2 25.5 13 3.7 25.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Paf1 PF03985.13 PSC68934.1 - 9.5 5.1 32.0 14 4.5 32.0 1.1 1 0 0 1 1 1 0 Paf1 GREB1 PF15782.5 PSC68934.1 - 9.6 3.2 26.8 13 2.7 26.8 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer GNT-I PF03071.15 PSC68935.1 - 3.3e-113 378.7 1.9 6.6e-113 377.7 0.0 1.9 2 0 0 2 2 2 1 GNT-I family Glyco_tranf_2_3 PF13641.6 PSC68935.1 - 0.0019 18.2 0.0 0.0041 17.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_8 PF01501.20 PSC68935.1 - 0.0042 16.7 1.1 0.0048 16.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferase family 8 Glycos_transf_2 PF00535.26 PSC68935.1 - 0.012 15.5 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Spt20 PF12090.8 PSC68935.1 - 0.51 9.9 11.3 50 3.4 13.1 2.2 2 0 0 2 2 2 0 Spt20 family RVT_2 PF07727.14 PSC68936.1 - 9.5e-30 104.0 0.0 1.5e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) FAD_binding_3 PF01494.19 PSC68936.1 - 1.4e-08 34.4 0.3 3.1e-08 33.2 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain RVT_1 PF00078.27 PSC68936.1 - 4.7e-05 23.0 0.0 0.015 14.8 0.0 2.2 2 0 0 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) Aminotran_5 PF00266.19 PSC68937.1 - 1.4e-43 149.3 0.0 1.6e-43 149.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 PSC68937.1 - 0.015 13.9 0.0 0.02 13.5 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 PSC68937.1 - 0.19 11.0 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase PAS_9 PF13426.7 PSC68938.1 - 1.9e-28 98.7 0.0 3.8e-13 49.6 0.0 2.2 2 0 0 2 2 2 2 PAS domain PAS PF00989.25 PSC68938.1 - 1.1e-07 31.9 0.0 0.023 14.7 0.0 2.5 2 1 0 2 2 2 2 PAS fold PAS_3 PF08447.12 PSC68938.1 - 2e-06 28.0 0.0 0.0027 18.0 0.0 2.9 2 1 0 2 2 2 2 PAS fold PAS_4 PF08448.10 PSC68938.1 - 7.4e-06 26.2 0.0 0.11 12.7 0.0 2.6 2 0 0 2 2 2 2 PAS fold Aminotran_5 PF00266.19 PSC68939.1 - 1.1e-34 120.0 0.0 1.6e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V SRPRB PF09439.10 PSC68940.1 - 2.1e-30 105.5 0.0 3.8e-30 104.7 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 PSC68940.1 - 1.7e-09 37.4 0.0 9.1e-09 35.0 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PSC68940.1 - 1.6e-06 27.8 0.0 1.1e-05 25.0 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PSC68940.1 - 3.7e-05 23.8 0.0 6.2e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 PSC68940.1 - 0.002 18.6 0.1 0.012 16.1 0.1 2.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Roc PF08477.13 PSC68940.1 - 0.0038 17.4 0.0 0.0063 16.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 PSC68940.1 - 0.3 10.4 0.0 1.9 7.8 0.0 1.9 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Ldh_1_C PF02866.18 PSC68941.1 - 6.3e-35 120.6 0.0 9.4e-35 120.0 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 PSC68941.1 - 9.3e-34 116.5 0.0 1.3e-33 116.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain PRA-PH PF01503.17 PSC68941.1 - 0.16 12.4 0.0 0.35 11.4 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosyl-ATP pyrophosphohydrolase Sugar_tr PF00083.24 PSC68942.1 - 4.7e-32 111.4 17.6 6.4e-19 68.1 2.7 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter Histone PF00125.24 PSC68943.1 - 5.7e-16 59.1 0.0 1.2e-15 58.0 0.0 1.5 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 PSC68943.1 - 6.9e-12 44.9 0.8 1.3e-11 44.0 0.8 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A DUF3245 PF11595.8 PSC68943.1 - 0.00057 20.4 0.7 0.0024 18.4 0.7 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3245) CBFD_NFYB_HMF PF00808.23 PSC68943.1 - 0.021 15.1 0.0 0.039 14.2 0.0 1.5 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Acyl-CoA_dh_1 PF00441.24 PSC68944.1 - 8e-45 152.7 2.6 8e-45 152.7 2.6 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PSC68944.1 - 2.2e-30 105.6 0.3 1.2e-29 103.3 0.0 2.5 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 PSC68944.1 - 2.1e-24 85.6 0.0 5.7e-24 84.1 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain FAD_binding_3 PF01494.19 PSC68944.1 - 2.1e-18 66.7 0.1 9.2e-18 64.6 0.1 2.1 1 1 0 1 1 1 1 FAD binding domain Acyl-CoA_dh_2 PF08028.11 PSC68944.1 - 7.4e-17 61.9 1.6 7.4e-17 61.9 1.6 2.8 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Thi4 PF01946.17 PSC68944.1 - 4.5e-08 32.6 0.3 9e-08 31.6 0.3 1.4 1 0 0 1 1 1 1 Thi4 family IGPS PF00218.21 PSC68944.1 - 6.8e-06 25.4 0.0 2.5e-05 23.6 0.0 1.9 1 1 0 1 1 1 1 Indole-3-glycerol phosphate synthase NAD_binding_8 PF13450.6 PSC68944.1 - 9.6e-05 22.5 0.3 0.00069 19.8 0.2 2.7 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 PSC68944.1 - 0.00024 20.3 0.7 0.00071 18.7 0.5 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 PSC68944.1 - 0.00034 19.9 0.4 0.00069 18.9 0.4 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PSC68944.1 - 0.0017 17.2 0.7 0.0039 15.9 0.7 1.6 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 PSC68944.1 - 0.0017 17.5 1.1 0.0034 16.5 1.1 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 PSC68944.1 - 0.035 13.7 4.8 0.035 13.7 0.6 2.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 PSC68944.1 - 0.053 13.5 1.2 0.11 12.4 0.2 2.1 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_oxidored PF12831.7 PSC68944.1 - 0.074 12.4 2.3 0.12 11.6 2.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Trp_halogenase PF04820.14 PSC68944.1 - 0.2 10.5 0.3 0.48 9.2 0.2 1.7 2 0 0 2 2 2 0 Tryptophan halogenase CN_hydrolase PF00795.22 PSC68945.1 - 1.9e-62 211.0 0.0 2.2e-62 210.8 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Peptidase_C12 PF01088.21 PSC68946.1 - 6.4e-67 225.4 0.0 9.1e-67 224.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 PSC68946.1 - 3.6e-18 65.2 0.5 3.6e-18 65.2 0.5 2.2 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases APG6_N PF17675.1 PSC68946.1 - 0.38 11.3 5.1 0.69 10.4 5.1 1.5 1 1 0 1 1 1 0 Apg6 coiled-coil region Spt20 PF12090.8 PSC68947.1 - 1.1 8.8 5.4 2.2 7.8 5.4 1.4 1 0 0 1 1 1 0 Spt20 family PMSR PF01625.21 PSC68949.1 - 9.8e-60 201.2 4.1 2.5e-59 199.9 4.1 1.7 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase FKBP_C PF00254.28 PSC68949.1 - 1.9e-09 37.7 0.0 3.9e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase zf-RING_2 PF13639.6 PSC68950.1 - 0.99 9.8 13.5 0.23 11.8 5.4 2.5 2 0 0 2 2 2 0 Ring finger domain 2-Hacid_dh_C PF02826.19 PSC68951.1 - 3e-46 157.0 0.1 1.3e-45 154.9 0.1 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PSC68951.1 - 1.1e-13 50.9 0.0 1.5e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 PSC68951.1 - 0.05 13.8 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Glyco_transf_15 PF01793.16 PSC68952.1 - 4.5e-87 292.3 0.0 3.9e-86 289.2 0.0 1.9 1 1 0 1 1 1 1 Glycolipid 2-alpha-mannosyltransferase Rieske PF00355.26 PSC68953.1 - 1.6e-10 40.7 0.0 3.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 PSC68953.1 - 0.0018 18.4 0.0 0.0032 17.6 0.0 1.4 1 0 0 1 1 1 1 Pheophorbide a oxygenase KDZ PF18758.1 PSC68954.1 - 1.8e-14 53.9 2.4 1.1e-08 34.9 0.6 2.7 2 1 1 3 3 3 2 Kyakuja-Dileera-Zisupton transposase Sigma54_CBD PF04963.13 PSC68954.1 - 0.62 9.9 3.0 0.98 9.2 0.0 2.7 4 0 0 4 4 4 0 Sigma-54 factor, core binding domain TPR_12 PF13424.6 PSC68955.1 - 1.3e-05 25.3 12.6 8.1e-05 22.8 2.2 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PSC68955.1 - 0.00092 19.2 1.8 3.6 7.9 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 PSC68955.1 - 0.0041 17.2 0.1 0.057 13.7 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 PSC68955.1 - 0.021 14.7 0.0 1.9 8.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 PSC68955.1 - 0.068 13.2 1.9 0.45 10.7 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Nbs1_C PF08599.10 PSC68955.1 - 0.085 13.0 0.3 0.93 9.7 1.3 2.2 2 0 0 2 2 2 0 DNA damage repair protein Nbs1 DUF4079 PF13301.6 PSC68955.1 - 0.12 12.5 0.2 0.27 11.4 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4079) TPR_10 PF13374.6 PSC68955.1 - 0.15 12.0 9.7 2 8.4 0.5 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat T3SS_basalb_I PF17001.5 PSC68955.1 - 0.56 10.8 2.2 1.5 9.5 0.0 2.8 4 0 0 4 4 4 0 Type III secretion basal body protein I, YscI, HrpB, PscI rRNA_processing PF08524.11 PSC68956.1 - 2.4e-10 40.6 36.4 3.5e-10 40.1 14.5 2.1 1 1 1 2 2 2 2 rRNA processing Peptidase_C1 PF00112.23 PSC68956.1 - 0.99 9.4 4.4 0.53 10.3 1.1 2.0 2 1 0 2 2 2 0 Papain family cysteine protease YlmH_RBD PF17774.1 PSC68957.1 - 8.5e-10 38.8 0.0 1.5e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Putative RNA-binding domain in YlmH S4 PF01479.25 PSC68957.1 - 0.00011 21.8 0.1 0.00021 20.9 0.1 1.5 1 0 0 1 1 1 1 S4 domain DUF1062 PF06353.12 PSC68957.1 - 0.12 13.2 0.0 0.19 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1062) VSP PF03302.13 PSC68958.1 - 0.00034 19.6 94.4 0.003 16.5 30.5 4.3 1 1 3 4 4 4 3 Giardia variant-specific surface protein VSP PF03302.13 PSC68959.1 - 0.00038 19.4 94.3 0.0015 17.5 20.9 4.3 1 1 3 4 4 4 3 Giardia variant-specific surface protein Ubie_methyltran PF01209.18 PSC68960.1 - 2.3e-88 295.4 0.0 4.2e-88 294.6 0.0 1.4 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 PSC68960.1 - 3.8e-16 59.6 0.0 3e-14 53.5 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC68960.1 - 8.5e-16 58.4 0.0 2.3e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC68960.1 - 3.9e-08 34.0 0.0 3.7e-06 27.6 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC68960.1 - 5.5e-07 29.6 0.0 9.4e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC68960.1 - 2e-06 27.7 0.0 3e-05 23.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain VCX_VCY PF15231.6 PSC68960.1 - 7.4 7.3 10.0 0.66 10.7 5.3 1.6 2 0 0 2 2 2 0 Variable charge X/Y family ADH_N PF08240.12 PSC68961.1 - 2.3e-23 82.2 1.3 5e-23 81.1 1.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PSC68961.1 - 1.5e-19 70.2 0.1 2.8e-19 69.4 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PSC68961.1 - 0.0038 18.3 0.0 0.0073 17.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 PSC68961.1 - 0.012 15.0 1.2 0.022 14.0 1.0 1.6 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 PSC68961.1 - 0.054 12.9 0.1 0.088 12.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short_C2 PF13561.6 PSC68961.1 - 0.083 12.4 0.2 0.19 11.3 0.2 1.5 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase TrkA_N PF02254.18 PSC68961.1 - 0.099 12.9 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 PSC68961.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PEP-CTERM PF07589.11 PSC68961.1 - 0.12 12.5 0.1 0.37 10.9 0.1 1.9 1 0 0 1 1 1 0 PEP-CTERM motif FtsJ PF01728.19 PSC68961.1 - 0.17 12.0 0.0 0.64 10.1 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase RraA-like PF03737.15 PSC68962.1 - 4.7e-41 140.4 0.6 5.5e-41 140.2 0.6 1.0 1 0 0 1 1 1 1 Aldolase/RraA Ldh_1_N PF00056.23 PSC68963.1 - 3.4e-48 163.3 1.0 5.5e-48 162.6 1.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Ldh_1_C PF02866.18 PSC68963.1 - 7.5e-45 152.9 0.0 1.4e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Rad21_Rec8 PF04824.16 PSC68963.1 - 6e-09 35.1 0.0 1.5e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein Rad21_Rec8_N PF04825.13 PSC68963.1 - 4.5e-08 33.3 0.0 8.6e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein 3Beta_HSD PF01073.19 PSC68963.1 - 0.001 18.1 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family THF_DHG_CYH_C PF02882.19 PSC68963.1 - 0.03 13.6 0.2 0.085 12.2 0.2 1.7 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain HA2 PF04408.23 PSC68964.1 - 7e-24 84.2 0.1 1.3e-23 83.3 0.1 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PSC68964.1 - 2.7e-20 72.5 0.0 8e-20 71.0 0.0 1.8 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PSC68964.1 - 2.2e-12 47.3 0.0 4.6e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PSC68964.1 - 4e-09 36.5 0.1 8.9e-09 35.4 0.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PSC68964.1 - 6.1e-07 29.8 0.0 2.4e-06 27.9 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.6 PSC68964.1 - 1.4e-05 25.4 0.1 3.2e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 PSC68964.1 - 2.8e-05 24.2 0.3 0.0011 19.0 0.3 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 PSC68964.1 - 0.00011 22.0 0.2 0.0002 21.1 0.2 1.3 1 0 0 1 1 1 1 AAA domain Flavi_DEAD PF07652.14 PSC68964.1 - 0.00085 19.3 0.1 0.0018 18.3 0.1 1.5 1 0 0 1 1 1 1 Flavivirus DEAD domain IstB_IS21 PF01695.17 PSC68964.1 - 0.00093 19.0 0.1 0.25 11.1 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein SRP54 PF00448.22 PSC68964.1 - 0.0013 18.4 0.4 0.0036 17.0 0.4 1.8 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain ABC_tran PF00005.27 PSC68964.1 - 0.0038 17.7 0.1 0.038 14.5 0.0 2.2 2 0 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 PSC68964.1 - 0.012 15.9 0.1 0.042 14.2 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain T2SSE PF00437.20 PSC68964.1 - 0.013 14.6 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Helicase_RecD PF05127.14 PSC68964.1 - 0.016 15.1 0.1 0.061 13.2 0.1 2.0 2 0 0 2 2 2 0 Helicase AAA PF00004.29 PSC68964.1 - 0.022 15.2 0.4 0.2 12.1 0.4 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 PSC68964.1 - 0.033 13.7 0.0 0.066 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 PSC68964.1 - 0.049 13.1 0.1 0.24 10.8 0.1 2.1 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 PSC68964.1 - 0.053 12.8 0.0 0.082 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 PSC68964.1 - 0.071 13.0 0.1 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 NACHT domain TrwB_AAD_bind PF10412.9 PSC68964.1 - 0.089 11.7 0.1 0.15 10.9 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 PSC68964.1 - 0.11 12.2 0.0 0.19 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 PSC68964.1 - 0.13 12.2 0.0 0.31 11.1 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 PSC68964.1 - 0.15 12.1 0.1 2 8.4 0.1 2.4 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 PSC68964.1 - 0.17 11.2 0.0 0.32 10.3 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATPase PF06745.13 PSC68964.1 - 0.17 11.2 0.0 0.36 10.2 0.0 1.4 1 0 0 1 1 1 0 KaiC cobW PF02492.19 PSC68964.1 - 0.18 11.4 0.1 2.2 7.8 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain RCC_reductase PF06405.11 PSC68965.1 - 8.7e-05 21.8 0.0 0.00011 21.5 0.0 1.2 1 0 0 1 1 1 1 Red chlorophyll catabolite reductase (RCC reductase) DNA_ligase_aden PF01653.18 PSC68965.1 - 0.16 11.1 0.0 0.24 10.4 0.0 1.2 1 0 0 1 1 1 0 NAD-dependent DNA ligase adenylation domain OTU PF02338.19 PSC68966.1 - 1e-10 42.2 0.0 6.8e-10 39.5 0.0 2.4 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PSC68966.1 - 2.3e-05 24.0 0.4 0.0029 17.1 0.0 2.8 2 1 1 3 3 3 2 Peptidase C65 Otubain FlxA PF14282.6 PSC68966.1 - 0.0014 18.5 4.8 0.0014 18.5 4.8 5.4 4 2 1 5 5 5 2 FlxA-like protein DUF2205 PF10224.9 PSC68967.1 - 3.4 7.7 5.5 4.9 7.2 0.4 3.2 3 0 0 3 3 3 0 Short coiled-coil protein Lipase_3 PF01764.25 PSC68968.1 - 5.4e-16 58.7 0.0 3.4e-15 56.1 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.8 PSC68968.1 - 0.29 10.6 0.0 0.45 10.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) TPR_19 PF14559.6 PSC68969.1 - 5.1e-09 36.5 34.1 0.02 15.4 5.3 5.7 3 2 2 5 5 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 PSC68969.1 - 4.3e-06 27.3 11.0 4.3e-06 27.3 11.0 7.9 6 3 3 9 9 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 PSC68969.1 - 1.7e-05 24.9 14.6 0.0069 16.6 2.6 3.7 3 1 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 PSC68969.1 - 0.0015 19.2 7.2 0.0086 16.8 3.6 8.9 6 3 4 10 10 10 4 Tetratricopeptide repeat TPR_2 PF07719.17 PSC68969.1 - 3.3 8.1 31.1 2.7 8.3 1.0 6.6 6 0 0 6 6 6 0 Tetratricopeptide repeat Alpha-amylase PF00128.24 PSC68970.1 - 5.2e-29 101.9 0.0 1.6e-28 100.2 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glycos_transf_1 PF00534.20 PSC68970.1 - 3.9e-07 29.7 0.0 7.7e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 DEAD PF00270.29 PSC68971.1 - 1.1e-39 136.0 0.1 2.1e-39 135.1 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC68971.1 - 1.7e-27 95.9 0.1 4.1e-26 91.5 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Bactofilin PF04519.13 PSC68971.1 - 0.017 15.4 5.1 0.18 12.1 1.4 3.8 2 2 2 4 4 4 0 Polymer-forming cytoskeletal AAA_22 PF13401.6 PSC68971.1 - 0.018 15.3 0.0 0.058 13.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sulfotransfer_2 PF03567.14 PSC68972.1 - 0.0014 18.6 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family SOR_SNZ PF01680.17 PSC68973.1 - 5.9e-111 369.2 9.4 7.9e-111 368.8 9.4 1.2 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 PSC68973.1 - 4.6e-09 36.0 9.0 5.9e-07 29.1 0.4 2.5 2 1 0 2 2 2 2 Thiazole biosynthesis protein ThiG TetR_C_27 PF17935.1 PSC68973.1 - 0.00021 21.3 0.0 0.00061 19.8 0.0 1.7 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain Dus PF01207.17 PSC68973.1 - 0.00028 20.1 0.3 0.51 9.4 0.0 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) NanE PF04131.14 PSC68973.1 - 0.0011 18.2 0.9 0.17 11.1 0.0 2.5 2 1 0 2 2 2 2 Putative N-acetylmannosamine-6-phosphate epimerase IGPS PF00218.21 PSC68973.1 - 0.013 14.7 0.1 0.42 9.7 0.0 2.4 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase His_biosynth PF00977.21 PSC68973.1 - 0.02 14.3 1.0 0.61 9.5 0.1 2.9 2 1 0 2 2 2 0 Histidine biosynthesis protein OMPdecase PF00215.24 PSC68973.1 - 0.023 14.3 0.3 1.2 8.7 0.0 2.4 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family NMO PF03060.15 PSC68973.1 - 0.38 10.1 7.8 0.81 9.0 0.3 2.3 2 0 0 2 2 2 0 Nitronate monooxygenase Gpr1_Fun34_YaaH PF01184.19 PSC68974.1 - 4.7e-28 98.2 21.0 7.8e-28 97.5 21.0 1.3 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family DUF1722 PF08349.11 PSC68974.1 - 0.089 13.1 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) QCR10 PF09796.9 PSC68974.1 - 0.59 10.2 2.8 0.97 9.5 0.0 2.8 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) PaO PF08417.12 PSC68975.1 - 5.3e-12 45.7 0.0 1e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Pheophorbide a oxygenase Rieske PF00355.26 PSC68975.1 - 8.7e-09 35.2 1.4 4.8e-07 29.6 0.0 2.8 3 0 0 3 3 3 1 Rieske [2Fe-2S] domain DUF983 PF06170.12 PSC68975.1 - 0.1 13.0 6.7 0.29 11.6 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF983) MliC PF09864.9 PSC68975.1 - 0.16 11.9 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme SP_C-Propep PF08999.10 PSC68975.1 - 0.71 9.7 8.4 1.7 8.5 8.4 1.6 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide UPF0506 PF11703.8 PSC68976.1 - 7.5e-05 23.0 59.7 0.013 15.9 16.8 4.3 1 1 3 4 4 4 4 UPF0506 Conotoxin_I2 PF17557.2 PSC68976.1 - 0.00023 21.2 6.9 0.00023 21.2 6.9 6.0 3 2 2 5 5 5 4 I2-superfamily conotoxins Toxin_12 PF07740.12 PSC68976.1 - 0.1 13.3 7.4 0.1 13.3 7.4 5.9 3 1 1 5 5 5 0 Ion channel inhibitory toxin Dickkopf_N PF04706.12 PSC68976.1 - 1.6 9.3 59.3 0.37 11.3 18.6 4.6 3 2 1 4 4 4 0 Dickkopf N-terminal cysteine-rich region DUF676 PF05057.14 PSC68977.1 - 2.3e-27 95.9 0.0 9.6e-26 90.6 0.0 2.3 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 PSC68977.1 - 5.9e-05 22.8 0.8 5.9e-05 22.8 0.8 2.6 3 1 0 3 3 3 1 alpha/beta hydrolase fold PGAP1 PF07819.13 PSC68977.1 - 0.0016 18.2 0.0 0.0041 16.9 0.0 1.6 1 1 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 PSC68977.1 - 0.02 14.1 0.0 0.037 13.3 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Spt20 PF12090.8 PSC68977.1 - 2.3 7.7 21.7 1.3 8.6 4.6 2.1 2 0 0 2 2 2 0 Spt20 family MTHFR PF02219.17 PSC68978.1 - 4.9e-119 396.9 0.0 5.6e-119 396.7 0.0 1.0 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Radical_SAM PF04055.21 PSC68978.1 - 0.12 12.8 0.0 0.31 11.4 0.0 1.8 1 1 0 1 1 1 0 Radical SAM superfamily DUF1604 PF07713.13 PSC68979.1 - 1.5e-35 120.9 0.7 7.9e-35 118.5 0.7 2.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) Surp PF01805.20 PSC68979.1 - 3.8e-12 46.0 0.1 7.1e-12 45.1 0.1 1.5 1 0 0 1 1 1 1 Surp module G-patch PF01585.23 PSC68979.1 - 2.2e-06 27.4 0.0 9e-06 25.5 0.0 2.1 1 0 0 1 1 1 1 G-patch domain Vfa1 PF08432.10 PSC68979.1 - 3.1 8.1 10.8 14 6.0 10.8 2.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF1604 PF07713.13 PSC68980.1 - 1.3e-35 121.1 0.7 7.8e-35 118.6 0.7 2.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1604) Surp PF01805.20 PSC68980.1 - 3.8e-12 46.0 0.1 7e-12 45.2 0.1 1.5 1 0 0 1 1 1 1 Surp module G-patch PF01585.23 PSC68980.1 - 2.2e-06 27.5 0.0 8.9e-06 25.5 0.0 2.1 1 0 0 1 1 1 1 G-patch domain MLIP PF15274.6 PSC68980.1 - 0.022 14.7 0.2 0.047 13.6 0.2 1.6 1 0 0 1 1 1 0 Muscular LMNA-interacting protein DUF4680 PF15730.5 PSC68981.1 - 0.39 11.1 1.1 3 8.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4680) RCC_reductase PF06405.11 PSC68982.1 - 0.00021 20.6 0.0 0.00038 19.7 0.0 1.3 1 0 0 1 1 1 1 Red chlorophyll catabolite reductase (RCC reductase) DUF3948 PF13134.6 PSC68982.1 - 0.038 13.7 0.5 0.1 12.3 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3948) rve PF00665.26 PSC68983.1 - 8.3e-19 67.9 0.0 1.8e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC68983.1 - 0.0066 16.2 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain CBS PF00571.28 PSC68984.1 - 1.6e-22 79.7 1.2 2.5e-07 31.1 0.1 4.5 4 0 0 4 4 4 4 CBS domain Pkinase PF00069.25 PSC68985.1 - 6e-42 143.8 0.0 2.4e-21 76.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC68985.1 - 2e-11 43.7 0.0 5.9e-05 22.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase SPICE PF15678.5 PSC68985.1 - 0.0049 16.3 0.2 0.0049 16.3 0.2 1.9 2 0 0 2 2 2 1 Centriole duplication and mitotic chromosome congression APH PF01636.23 PSC68985.1 - 0.02 14.8 2.8 0.8 9.6 0.0 3.1 2 1 1 3 3 3 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PSC68985.1 - 4 6.1 7.9 0.17 10.7 0.1 2.5 2 2 0 2 2 2 0 Fungal protein kinase Ribosomal_S11 PF00411.19 PSC68986.1 - 6e-47 158.6 0.7 9e-47 158.0 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S11 CBM_25 PF03423.13 PSC68986.1 - 0.054 13.8 0.0 0.1 12.8 0.0 1.4 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) Nipped-B_C PF12830.7 PSC68988.1 - 5.2e-27 95.0 0.0 2.8e-24 86.1 0.0 2.6 2 0 0 2 2 2 2 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 PSC68988.1 - 6e-12 45.6 2.3 4e-07 30.2 1.0 2.8 2 0 0 2 2 2 2 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 PSC68988.1 - 8.9e-07 28.7 13.0 0.16 12.3 0.1 7.1 7 0 0 7 7 7 2 HEAT repeat Cnd3 PF12719.7 PSC68988.1 - 0.052 12.7 1.3 0.075 12.2 0.0 1.9 2 0 0 2 2 2 0 Nuclear condensing complex subunits, C-term domain Adaptin_N PF01602.20 PSC68988.1 - 0.084 11.4 0.0 0.92 8.0 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region Cnd1 PF12717.7 PSC68988.1 - 0.087 12.9 0.2 0.64 10.1 0.0 2.4 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 PSC68988.1 - 0.14 12.3 0.1 0.14 12.3 0.1 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 PSC68988.1 - 1.4 9.5 27.0 0.27 11.8 0.2 8.0 6 1 2 8 8 8 0 HEAT-like repeat CDC27 PF09507.10 PSC68988.1 - 2.2 7.5 9.6 4.7 6.5 9.6 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFIIA PF03153.13 PSC68989.1 - 0.089 12.8 8.9 0.092 12.7 8.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 PSC68989.1 - 0.9 9.5 3.6 1.2 9.1 3.6 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Phage_tail_APC PF16778.5 PSC68990.1 - 0.025 14.5 0.1 16 5.5 0.0 3.0 3 0 0 3 3 3 0 Phage tail assembly chaperone protein TP_methylase PF00590.20 PSC68991.1 - 2.5e-38 132.2 5.6 2.5e-38 132.2 5.6 3.9 5 1 0 5 5 5 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Rhodanese_C PF12368.8 PSC68991.1 - 3.9e-16 59.2 10.3 9e-16 58.0 10.3 1.7 1 0 0 1 1 1 1 Rhodanase C-terminal UPF0176_N PF17773.1 PSC68991.1 - 4.1e-12 46.3 0.0 1.3e-11 44.7 0.0 2.0 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain Rhodanese PF00581.20 PSC68991.1 - 6.1e-10 39.6 0.0 6.5e-09 36.3 0.0 2.5 2 0 0 2 2 2 1 Rhodanese-like domain DUF3455 PF11937.8 PSC68991.1 - 3.4e-07 30.8 0.1 1.3e-06 28.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3455) TPR_12 PF13424.6 PSC68991.1 - 8e-07 29.3 0.1 8e-07 29.3 0.1 4.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 PSC68991.1 - 1.4 9.2 7.4 11 6.4 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Cyd_oper_YbgE PF09600.10 PSC68992.1 - 0.37 11.2 4.2 0.14 12.6 1.1 1.9 2 0 0 2 2 2 0 Cyd operon protein YbgE (Cyd_oper_YbgE) PALP PF00291.25 PSC68993.1 - 4e-36 124.9 0.9 5.7e-36 124.4 0.9 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme PSI_PsaH PF03244.14 PSC68993.1 - 2.4e-34 117.8 0.1 5.2e-34 116.7 0.1 1.5 1 0 0 1 1 1 1 Photosystem I reaction centre subunit VI tRNA_m1G_MT PF01746.21 PSC68994.1 - 3e-30 105.4 0.1 5.7e-30 104.5 0.1 1.5 1 0 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase DUF3379 PF11859.8 PSC68994.1 - 0.04 13.3 0.0 0.04 13.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3379) Gly_transf_sug PF04488.15 PSC68995.1 - 3e-09 37.4 0.1 5.4e-09 36.6 0.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Adeno_VII PF03228.14 PSC68995.1 - 0.048 14.3 0.0 0.16 12.6 0.0 1.9 2 0 0 2 2 2 0 Adenoviral core protein VII Heliorhodopsin PF18761.1 PSC68996.1 - 8.3e-60 202.1 10.3 2.8e-33 115.2 0.1 2.0 2 0 0 2 2 2 2 Heliorhodopsin PAP2 PF01569.21 PSC68997.1 - 4.9e-16 58.7 7.3 1.5e-15 57.1 7.3 1.8 1 1 0 1 1 1 1 PAP2 superfamily DUF212 PF02681.14 PSC68997.1 - 0.0019 18.3 1.4 0.07 13.3 0.3 2.3 2 0 0 2 2 2 2 Divergent PAP2 family MARVEL PF01284.23 PSC68998.1 - 9.1e-06 25.8 12.6 1.4e-05 25.1 12.6 1.3 1 0 0 1 1 1 1 Membrane-associating domain DUF1467 PF07330.12 PSC68998.1 - 0.019 14.9 1.2 0.15 12.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1467) DUF2232 PF09991.9 PSC68998.1 - 0.061 12.5 3.1 0.44 9.7 0.1 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) ATP_bind_1 PF03029.17 PSC68999.1 - 2.7e-74 250.0 0.0 3.3e-74 249.7 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 PSC68999.1 - 6.9e-07 29.0 0.0 0.00026 20.6 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 PSC68999.1 - 4.3e-06 27.2 0.0 7.7e-05 23.1 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain MeaB PF03308.16 PSC68999.1 - 9.6e-05 21.5 0.2 0.11 11.4 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 PSC68999.1 - 0.00023 21.4 0.0 0.0013 19.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 PSC68999.1 - 0.00031 20.7 0.0 0.00055 19.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain MMR_HSR1 PF01926.23 PSC68999.1 - 0.00061 19.9 0.0 0.0045 17.0 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 PSC68999.1 - 0.00072 19.7 0.0 0.00072 19.7 0.0 1.8 2 0 0 2 2 1 1 AAA domain Arf PF00025.21 PSC68999.1 - 0.001 18.5 0.0 0.046 13.2 0.0 2.7 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_18 PF13238.6 PSC68999.1 - 0.0011 19.5 0.3 0.0037 17.8 0.0 2.0 3 0 0 3 3 1 1 AAA domain SRP54 PF00448.22 PSC68999.1 - 0.0013 18.4 0.0 0.0028 17.3 0.0 1.6 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain FeoB_N PF02421.18 PSC68999.1 - 0.0021 17.6 0.0 0.78 9.2 0.0 2.5 3 0 0 3 3 3 1 Ferrous iron transport protein B NB-ARC PF00931.22 PSC68999.1 - 0.0034 16.6 0.0 0.0061 15.8 0.0 1.3 1 0 0 1 1 1 1 NB-ARC domain cobW PF02492.19 PSC68999.1 - 0.0042 16.7 0.0 0.16 11.6 0.1 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.20 PSC68999.1 - 0.0047 16.1 0.0 0.091 11.9 0.0 2.2 2 0 0 2 2 2 1 G-protein alpha subunit RsgA_GTPase PF03193.16 PSC68999.1 - 0.0051 16.7 0.0 4.7 7.1 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase Zeta_toxin PF06414.12 PSC68999.1 - 0.0055 16.0 0.1 0.017 14.4 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.6 PSC68999.1 - 0.006 16.9 0.0 0.014 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PSC68999.1 - 0.0063 16.2 1.9 0.012 15.4 0.0 2.1 2 0 0 2 2 2 1 AAA domain FtsK_SpoIIIE PF01580.18 PSC68999.1 - 0.013 14.9 0.6 0.031 13.6 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family PduV-EutP PF10662.9 PSC68999.1 - 0.02 14.6 0.1 0.1 12.3 0.0 2.1 3 0 0 3 3 2 0 Ethanolamine utilisation - propanediol utilisation ATPase PF06745.13 PSC68999.1 - 0.025 13.9 0.0 0.059 12.7 0.0 1.6 2 0 0 2 2 2 0 KaiC AAA_24 PF13479.6 PSC68999.1 - 0.044 13.5 0.0 0.077 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.14 PSC68999.1 - 0.072 13.0 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SSE PF00437.20 PSC68999.1 - 0.079 12.0 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 PSC68999.1 - 0.084 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Viral_helicase1 PF01443.18 PSC68999.1 - 0.085 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase KTI12 PF08433.10 PSC68999.1 - 0.096 12.1 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Ras PF00071.22 PSC68999.1 - 0.1 12.2 0.0 11 5.6 0.0 2.3 1 1 1 2 2 2 0 Ras family PRK PF00485.18 PSC68999.1 - 0.11 12.2 0.0 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF87 PF01935.17 PSC68999.1 - 0.14 12.2 0.0 0.35 10.9 0.0 1.6 2 0 0 2 2 2 0 Helicase HerA, central domain TsaE PF02367.17 PSC68999.1 - 0.18 11.8 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_23 PF13476.6 PSC68999.1 - 0.19 12.2 0.0 1.7 9.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain Pox_A32 PF04665.12 PSC68999.1 - 0.19 11.1 0.0 0.36 10.3 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein AAA_28 PF13521.6 PSC68999.1 - 0.2 11.9 2.2 0.66 10.2 0.0 2.4 2 1 1 3 3 2 0 AAA domain Alpha-amylase_C PF02806.18 PSC69000.1 - 3.1e-24 85.3 0.6 7.5e-23 80.8 0.2 2.5 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 PSC69000.1 - 2.4e-12 47.0 0.3 5.2e-12 45.9 0.3 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 PSC69000.1 - 3.2e-12 46.7 2.2 5.5e-11 42.6 0.1 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 PSC69000.1 - 0.012 14.7 0.3 0.037 13.1 0.0 1.8 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain Alpha-amylase_C PF02806.18 PSC69001.1 - 3e-24 85.3 0.6 7.3e-23 80.9 0.2 2.5 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 PSC69001.1 - 2.3e-12 47.1 0.3 5.2e-12 46.0 0.3 1.6 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 PSC69001.1 - 3.2e-12 46.7 2.2 6.2e-11 42.5 0.2 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain hDGE_amylase PF14701.6 PSC69001.1 - 0.012 14.7 0.3 0.036 13.2 0.0 1.8 2 0 0 2 2 2 0 Glycogen debranching enzyme, glucanotransferase domain Nup192 PF11894.8 PSC69002.1 - 4.3e-79 266.2 0.0 4.3e-65 219.8 0.0 2.2 2 0 0 2 2 2 2 Nuclear pore complex scaffold, nucleoporins 186/192/205 DUF1804 PF08822.11 PSC69002.1 - 0.055 13.4 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) DcpS_C PF11969.8 PSC69003.1 - 5.6e-17 62.3 0.1 9.6e-17 61.5 0.1 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Methyltransf_24 PF13578.6 PSC69003.1 - 5.7e-13 49.8 0.0 1.6e-12 48.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain HIT PF01230.23 PSC69003.1 - 1.9e-05 25.3 3.0 6e-05 23.7 3.0 1.8 1 1 0 1 1 1 1 HIT domain EamA PF00892.20 PSC69004.1 - 6.7e-29 100.8 22.9 6.9e-17 61.9 13.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family CBM_20 PF00686.19 PSC69004.1 - 1.3e-10 41.1 0.1 2.3e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 Starch binding domain AMPK1_CBM PF16561.5 PSC69004.1 - 0.0023 18.1 0.0 0.0046 17.1 0.0 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase ABC_tran_2 PF16949.5 PSC69004.1 - 0.024 13.5 7.3 0.037 12.8 7.3 1.2 1 0 0 1 1 1 0 Putative ATP-binding cassette DUF3021 PF11457.8 PSC69004.1 - 1.2 9.5 7.6 3.3 8.1 7.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) PI3_PI4_kinase PF00454.27 PSC69006.1 - 3.8e-32 112.1 0.0 8.5e-30 104.4 0.0 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 PSC69006.1 - 0.0011 18.4 0.0 0.0023 17.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) E_raikovi_mat PF06360.11 PSC69006.1 - 0.72 10.3 4.0 21 5.6 0.1 2.7 2 0 0 2 2 2 0 Euplotes raikovi mating pheromone Methyltransf_11 PF08241.12 PSC69007.1 - 4.2e-18 65.8 0.0 1e-17 64.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC69007.1 - 7.2e-16 58.7 0.0 1.5e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC69007.1 - 1.2e-12 47.9 0.0 2e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC69007.1 - 2.2e-12 47.6 0.0 6e-12 46.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC69007.1 - 1e-08 35.2 0.0 1.5e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PSC69007.1 - 3.7e-06 26.6 0.0 5.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 PSC69007.1 - 7.1e-05 22.2 0.0 0.00014 21.2 0.0 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 PSC69007.1 - 0.0038 16.6 0.0 0.0054 16.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 PSC69007.1 - 0.0091 15.9 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 PSC69007.1 - 0.021 14.1 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase domain PrmA PF06325.13 PSC69007.1 - 0.033 13.6 0.0 0.05 13.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_PK PF05891.12 PSC69007.1 - 0.077 12.5 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_4 PF02390.17 PSC69007.1 - 0.093 12.2 0.0 0.41 10.1 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_8 PF05148.15 PSC69007.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 1 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_15 PF09445.10 PSC69007.1 - 0.13 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase NodS PF05401.11 PSC69007.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) EamA PF00892.20 PSC69008.1 - 1.8e-13 50.9 24.7 3.5e-08 33.7 10.8 2.9 3 0 0 3 3 3 2 EamA-like transporter family TMEM51 PF15345.6 PSC69008.1 - 0.0093 15.8 0.3 0.015 15.1 0.3 1.3 1 0 0 1 1 1 1 Transmembrane protein 51 DUF2722 PF10846.8 PSC69008.1 - 0.0098 14.9 1.0 0.012 14.6 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) SARAF PF06682.12 PSC69008.1 - 0.019 14.6 1.5 2.4 7.7 0.2 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4064 PF13273.6 PSC69008.1 - 0.079 13.2 3.1 0.21 11.9 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF4064) DUF4834 PF16118.5 PSC69008.1 - 0.11 13.4 0.7 0.2 12.6 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TFIIA PF03153.13 PSC69008.1 - 0.56 10.1 10.3 0.81 9.6 10.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Activator_LAG-3 PF11498.8 PSC69008.1 - 1.7 7.5 24.2 2.4 7.0 24.2 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF3458_C PF17432.2 PSC69009.1 - 1.8e-104 349.6 1.2 3.1e-104 348.8 1.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats FAM91_N PF14647.6 PSC69009.1 - 4.2e-84 282.5 0.0 6.1e-84 282.0 0.0 1.2 1 0 0 1 1 1 1 FAM91 N-terminus Peptidase_M1 PF01433.20 PSC69009.1 - 6.4e-48 163.2 0.0 9.4e-48 162.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain FAM91_C PF14648.6 PSC69009.1 - 1.2e-38 133.1 0.0 3.9e-34 118.2 0.0 2.1 2 0 0 2 2 2 2 FAM91 C-terminus DUF3458 PF11940.8 PSC69009.1 - 5.9e-28 97.2 0.0 1.5e-27 95.8 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 PSC69009.1 - 1.5e-11 44.8 0.0 2.4e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain EF-G-binding_N PF07299.11 PSC69009.1 - 0.078 13.5 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 Elongation factor G-binding protein, N-terminal Pex14_N PF04695.13 PSC69010.1 - 0.13 12.9 2.7 0.32 11.6 2.7 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SUR7 PF06687.12 PSC69010.1 - 0.24 11.0 4.7 0.34 10.5 4.7 1.2 1 0 0 1 1 1 0 SUR7/PalI family Rab5ip PF07019.12 PSC69010.1 - 1.8 9.2 5.0 1.9 9.1 2.9 2.1 2 1 0 2 2 2 0 Rab5-interacting protein (Rab5ip) Sec63 PF02889.16 PSC69011.1 - 1.4e-165 548.8 0.0 4.2e-89 298.1 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 PSC69011.1 - 1.3e-50 171.6 0.1 1.6e-25 89.9 0.1 2.7 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 PSC69011.1 - 1.2e-33 115.5 0.0 4.4e-33 113.8 0.0 2.0 1 0 0 1 1 1 1 N-terminal helicase PWI domain ResIII PF04851.15 PSC69011.1 - 1.5e-22 80.4 0.0 2.7e-12 47.0 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PSC69011.1 - 5.7e-14 52.4 0.0 6.7e-07 29.6 0.0 3.9 2 2 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 PSC69011.1 - 1.8e-06 28.2 0.2 0.16 12.2 0.0 3.5 2 2 0 2 2 2 2 AAA domain T2SSE PF00437.20 PSC69011.1 - 0.0045 16.1 0.0 1.4 7.9 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_11 PF13086.6 PSC69011.1 - 0.01 15.7 0.3 5.3 6.7 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 PSC69011.1 - 0.023 15.0 0.3 3.6 7.9 0.1 2.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 PSC69011.1 - 0.067 12.6 0.0 9.4 5.6 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein YL1 PF05764.13 PSC69011.1 - 0.11 12.6 5.6 0.23 11.6 5.6 1.4 1 0 0 1 1 1 0 YL1 nuclear protein DUF501 PF04417.12 PSC69011.1 - 0.24 11.2 1.5 0.7 9.7 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF501) DUF3611 PF12263.8 PSC69012.1 - 5.7e-40 137.1 11.3 7.1e-40 136.8 11.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) Phage_holin_2_3 PF16080.5 PSC69012.1 - 0.014 15.1 1.6 0.039 13.7 1.6 1.8 1 0 0 1 1 1 0 Bacteriophage holin family HP1 DUF3341 PF11821.8 PSC69012.1 - 0.045 13.4 4.9 0.097 12.3 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3341) DUF3611 PF12263.8 PSC69013.1 - 5.6e-40 137.1 11.3 7e-40 136.8 11.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3611) Phage_holin_2_3 PF16080.5 PSC69013.1 - 0.014 15.1 1.6 0.038 13.7 1.6 1.8 1 0 0 1 1 1 0 Bacteriophage holin family HP1 DUF3341 PF11821.8 PSC69013.1 - 0.044 13.4 4.9 0.096 12.3 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3341) Rdx PF10262.9 PSC69014.1 - 0.17 12.1 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Rdx family Sulfate_transp PF00916.20 PSC69015.1 - 2.5e-95 319.4 10.2 3.5e-95 319.0 10.2 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 PSC69015.1 - 1.8e-22 79.2 0.0 3.9e-22 78.1 0.0 1.6 2 0 0 2 2 2 1 STAS domain STAS_2 PF13466.6 PSC69015.1 - 0.00037 20.8 0.2 0.00086 19.6 0.2 1.6 1 0 0 1 1 1 1 STAS domain LSM PF01423.22 PSC69016.1 - 4.8e-19 67.8 0.2 5.4e-19 67.6 0.2 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 PSC69016.1 - 0.0016 18.6 0.0 0.0019 18.3 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Ala_racemase_N PF01168.20 PSC69017.1 - 1.7e-22 80.1 0.0 2e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain Lant_dehydr_N PF04738.13 PSC69017.1 - 0.055 11.5 0.3 0.067 11.3 0.3 1.1 1 0 0 1 1 1 0 Lantibiotic dehydratase, N terminus Fasciclin PF02469.22 PSC69018.1 - 8.1e-37 126.3 0.0 1.3e-22 80.4 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain Fasciclin PF02469.22 PSC69019.1 - 8.1e-37 126.3 0.0 1.3e-22 80.4 0.0 2.1 2 0 0 2 2 2 2 Fasciclin domain ATG16 PF08614.11 PSC69021.1 - 0.013 15.7 0.9 0.013 15.7 0.9 1.9 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Phage_GPO PF05929.11 PSC69021.1 - 0.038 13.6 0.2 0.062 12.9 0.2 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase CLZ PF16526.5 PSC69021.1 - 0.061 13.7 0.6 0.12 12.7 0.6 1.4 1 0 0 1 1 1 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spc7 PF08317.11 PSC69021.1 - 0.095 11.6 0.8 0.13 11.1 0.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 PSC69021.1 - 0.19 11.8 2.0 0.41 10.8 2.0 1.4 1 0 0 1 1 1 0 Tropomyosin like Lebercilin PF15619.6 PSC69021.1 - 0.25 11.0 1.4 0.38 10.4 1.4 1.2 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease TPR_MLP1_2 PF07926.12 PSC69021.1 - 0.43 10.6 7.6 0.82 9.7 7.6 1.4 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CEP63 PF17045.5 PSC69021.1 - 0.99 9.3 3.4 1.5 8.6 3.4 1.1 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa DUF3584 PF12128.8 PSC69021.1 - 1.2 6.6 5.1 1.6 6.2 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TMF_TATA_bd PF12325.8 PSC69021.1 - 1.2 9.4 4.6 2 8.7 4.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding SBP56 PF05694.11 PSC69022.1 - 3.8e-183 609.5 0.0 4.4e-183 609.3 0.0 1.0 1 0 0 1 1 1 1 56kDa selenium binding protein (SBP56) ECH_2 PF16113.5 PSC69023.1 - 3.5e-121 404.8 1.7 5.6e-121 404.1 0.0 2.3 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 PSC69023.1 - 7.6e-29 100.8 0.0 7.2e-28 97.6 0.0 2.6 2 0 0 2 2 2 1 Enoyl-CoA hydratase/isomerase FANCL_C PF11793.8 PSC69023.1 - 9.3e-06 25.7 5.3 2e-05 24.7 5.3 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 PSC69023.1 - 6.8e-05 23.1 8.5 0.00013 22.3 8.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-ANAPC11 PF12861.7 PSC69023.1 - 0.013 15.5 2.3 0.026 14.6 2.3 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 PSC69023.1 - 0.061 13.6 5.8 0.14 12.4 5.8 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain DUF3864 PF12980.7 PSC69023.1 - 0.092 13.1 0.0 10 6.5 0.0 2.6 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3864) zf-RING-like PF08746.11 PSC69023.1 - 0.11 12.9 7.4 0.21 11.9 7.4 1.5 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 PSC69023.1 - 0.17 11.8 5.1 0.42 10.6 5.1 1.7 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 PSC69023.1 - 0.4 10.6 6.5 0.11 12.4 1.8 2.3 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn-ribbon_8 PF09723.10 PSC69023.1 - 0.43 10.7 2.0 1.2 9.3 2.0 1.8 1 0 0 1 1 1 0 Zinc ribbon domain Zf_RING PF16744.5 PSC69023.1 - 0.57 10.3 3.0 1.6 8.9 3.0 1.8 1 0 0 1 1 1 0 KIAA1045 RING finger zf-C3HC4 PF00097.25 PSC69023.1 - 0.69 9.8 7.3 1.4 8.9 7.3 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Caudo_TAP PF02413.17 PSC69023.1 - 0.83 9.8 5.1 0.37 10.9 0.1 2.7 2 0 0 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK RINGv PF12906.7 PSC69023.1 - 0.86 9.8 6.7 2 8.6 6.7 1.7 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4_2 PF13923.6 PSC69023.1 - 1.7 8.6 7.3 3.6 7.5 7.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PSC69023.1 - 2.7 7.7 4.2 6 6.6 4.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4_3 PF13920.6 PSC69023.1 - 8.6 6.3 7.3 5.4 7.0 4.9 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF588 PF04535.12 PSC69024.1 - 0.0016 18.3 0.5 0.0016 18.3 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF588) zf-MYND PF01753.18 PSC69025.1 - 5.1e-06 26.5 18.7 5.1e-06 26.5 18.7 2.4 2 1 0 2 2 2 1 MYND finger SET PF00856.28 PSC69026.1 - 0.00035 21.0 0.0 0.00062 20.2 0.0 1.4 1 0 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 PSC69026.1 - 0.042 14.5 0.0 0.35 11.6 0.0 2.2 2 0 0 2 2 2 0 Rubisco LSMT substrate-binding Alpha-amyl_C2 PF07821.12 PSC69027.1 - 2e-19 69.5 0.2 5.1e-19 68.3 0.0 1.8 2 0 0 2 2 2 1 Alpha-amylase C-terminal beta-sheet domain Alpha-amylase PF00128.24 PSC69027.1 - 2.6e-16 60.1 0.0 4.1e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Alpha amylase, catalytic domain WD40 PF00400.32 PSC69028.1 - 1.3e-37 127.1 15.6 2.7e-07 31.2 0.5 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC69028.1 - 2.1e-15 56.8 2.5 0.0083 16.4 0.0 5.6 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PSC69028.1 - 9.6e-06 25.6 0.6 0.014 15.3 0.0 2.6 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PSC69028.1 - 0.15 10.9 0.4 50 2.7 0.0 3.3 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 PSC69028.1 - 0.17 11.2 0.0 12 5.1 0.0 2.1 2 0 0 2 2 2 0 WD40-like domain TGT PF01702.18 PSC69029.1 - 7.7e-100 334.4 0.0 6.1e-98 328.2 0.0 2.1 1 1 0 1 1 1 1 Queuine tRNA-ribosyltransferase Thioredoxin PF00085.20 PSC69029.1 - 8.6e-07 28.9 0.0 1.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin Mog1 PF04603.12 PSC69030.1 - 2.2e-35 122.0 0.0 2.6e-35 121.8 0.0 1.1 1 0 0 1 1 1 1 Ran-interacting Mog1 protein CDP-OH_P_transf PF01066.21 PSC69031.1 - 4.7e-10 40.1 0.6 4.7e-10 40.1 0.6 2.0 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Peptidase_C97 PF05903.14 PSC69031.1 - 0.15 11.8 0.0 0.27 11.1 0.0 1.4 1 0 0 1 1 1 0 PPPDE putative peptidase domain Hist_deacetyl PF00850.19 PSC69032.1 - 4.4e-80 269.4 0.0 5.4e-80 269.1 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain B12-binding PF02310.19 PSC69032.1 - 0.062 13.3 0.0 1.5 8.9 0.0 2.5 1 1 0 2 2 2 0 B12 binding domain FAD_binding_2 PF00890.24 PSC69033.1 - 2.9e-91 306.6 13.8 2.9e-91 306.6 13.8 1.9 2 0 0 2 2 2 1 FAD binding domain Succ_DH_flav_C PF02910.20 PSC69033.1 - 8.1e-15 55.0 0.0 1.6e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Ank PF00023.30 PSC69033.1 - 0.00012 22.3 3.3 0.0052 17.2 0.2 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 PSC69033.1 - 0.00035 20.8 1.0 0.011 16.1 0.2 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PSC69033.1 - 0.00045 20.7 0.2 0.019 15.5 0.1 3.1 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PSC69033.1 - 0.0054 17.1 0.2 0.26 12.0 0.0 3.7 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 PSC69033.1 - 0.0079 16.8 0.3 0.39 11.4 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Pyr_redox_2 PF07992.14 PSC69033.1 - 0.04 13.1 0.3 0.42 9.8 0.2 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FANC_SAP PF18081.1 PSC69033.1 - 1.3 9.3 5.4 1.7 8.8 2.2 3.1 2 0 0 2 2 2 0 Fanconi anemia-associated nuclease SAP domain Lycopene_cycl PF05834.12 PSC69034.1 - 1.8e-107 359.7 0.0 2.3e-107 359.3 0.0 1.1 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 PSC69034.1 - 8e-11 41.7 0.0 4e-06 26.3 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 PSC69034.1 - 4.6e-08 32.7 0.1 9.8e-08 31.6 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 PSC69034.1 - 5.3e-06 26.3 0.6 0.0013 18.3 0.3 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PSC69034.1 - 1e-05 24.8 0.6 1e-05 24.8 0.6 2.0 2 0 0 2 2 2 1 FAD binding domain NAD_binding_9 PF13454.6 PSC69034.1 - 1.4e-05 25.1 0.1 0.19 11.7 0.0 2.5 2 0 0 2 2 2 2 FAD-NAD(P)-binding HI0933_like PF03486.14 PSC69034.1 - 1.5e-05 23.9 0.3 0.00048 19.0 0.5 2.1 2 0 0 2 2 2 1 HI0933-like protein NAD_binding_8 PF13450.6 PSC69034.1 - 6e-05 23.2 0.9 0.00022 21.4 0.3 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 PSC69034.1 - 0.00013 21.3 0.0 0.00021 20.6 0.0 1.2 1 0 0 1 1 1 1 Thi4 family Trp_halogenase PF04820.14 PSC69034.1 - 0.00015 20.8 0.3 0.33 9.7 0.0 2.7 3 0 0 3 3 3 2 Tryptophan halogenase GIDA PF01134.22 PSC69034.1 - 0.0016 17.6 0.1 0.0027 16.9 0.1 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 PSC69034.1 - 0.0038 16.5 0.0 0.0056 16.0 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PSC69034.1 - 0.0085 16.6 0.1 0.024 15.2 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PSC69034.1 - 0.018 14.4 1.3 0.031 13.6 1.3 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase 3HCDH_N PF02737.18 PSC69034.1 - 0.031 14.2 0.1 0.059 13.2 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 PSC69034.1 - 0.13 12.2 0.1 0.22 11.5 0.1 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus OrfB_Zn_ribbon PF07282.11 PSC69034.1 - 0.16 11.9 0.1 1.5 8.8 0.0 2.2 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Hydrolase_like PF13242.6 PSC69035.1 - 2.1e-15 56.5 0.1 2.1e-15 56.5 0.1 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 PSC69035.1 - 2.3e-15 56.5 0.0 6.9e-15 55.0 0.0 1.9 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PSC69035.1 - 1.8e-11 44.8 1.5 3.7e-05 24.1 0.1 2.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PSC69035.1 - 3.5e-11 43.5 0.0 4.9e-07 30.0 0.0 2.1 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 PSC69035.1 - 0.00026 21.5 0.1 0.016 15.6 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cupin_8 PF13621.6 PSC69036.1 - 1.1e-25 90.8 0.0 7.1e-25 88.2 0.0 1.9 1 1 0 1 1 1 1 Cupin-like domain Pectate_lyase_3 PF12708.7 PSC69036.1 - 1.2e-18 67.8 0.1 5.8e-18 65.5 0.0 2.0 2 0 0 2 2 2 1 Pectate lyase superfamily protein Cupin_4 PF08007.12 PSC69036.1 - 2.5e-07 30.5 0.2 5.5e-07 29.4 0.2 1.5 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_1 PF00190.22 PSC69036.1 - 0.065 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Cupin End_N_terminal PF12218.8 PSC69036.1 - 0.18 11.6 0.7 0.42 10.3 0.7 1.6 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase TMEM247 PF15444.6 PSC69037.1 - 0.05 13.6 0.0 0.05 13.6 0.0 2.6 1 1 1 3 3 3 0 Transmembrane protein 247 Mito_carr PF00153.27 PSC69039.1 - 2.4e-48 162.0 2.2 2.2e-15 56.3 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein TrbI PF03743.14 PSC69039.1 - 2.5 7.9 8.0 0.43 10.4 2.4 2.2 1 1 0 2 2 2 0 Bacterial conjugation TrbI-like protein FBPase PF00316.20 PSC69040.1 - 5.2e-46 156.5 0.0 1.7e-45 154.9 0.0 1.9 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain RCR PF12273.8 PSC69040.1 - 0.11 13.2 5.1 0.32 11.7 5.1 1.7 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red PLAC9 PF15205.6 PSC69040.1 - 1.4 9.4 5.7 4.5 7.7 0.0 4.1 4 0 0 4 4 4 0 Placenta-specific protein 9 NIPSNAP PF07978.13 PSC69041.1 - 3.4e-31 107.5 0.0 1.7e-16 60.3 0.0 2.5 2 0 0 2 2 2 2 NIPSNAP FlgD_ig PF13860.6 PSC69041.1 - 0.00019 21.2 0.4 39 4.2 0.0 5.0 1 1 4 5 5 5 3 FlgD Ig-like domain Apolipoprotein PF01442.18 PSC69041.1 - 0.002 18.0 0.1 0.01 15.7 0.0 2.2 2 1 0 2 2 2 1 Apolipoprotein A1/A4/E domain FA_FANCE PF11510.8 PSC69042.1 - 1.9e-09 37.2 1.8 1.8e-08 34.1 1.8 2.3 1 1 0 1 1 1 1 Fanconi Anaemia group E protein FANCE TPR_1 PF00515.28 PSC69042.1 - 0.00028 20.6 0.7 0.42 10.5 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 PSC69042.1 - 0.00034 20.8 35.9 0.018 15.3 0.8 6.8 6 2 2 8 8 8 4 Tetratricopeptide repeat SPO22 PF08631.10 PSC69042.1 - 0.079 12.4 0.2 0.35 10.3 0.0 2.0 2 1 0 2 2 2 0 Meiosis protein SPO22/ZIP4 like TPR_10 PF13374.6 PSC69042.1 - 1.1 9.2 0.0 1.1 9.2 0.0 5.5 8 0 0 8 8 8 0 Tetratricopeptide repeat Acetyltransf_1 PF00583.25 PSC69043.1 - 1.7e-15 57.3 0.0 2.2e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PSC69043.1 - 3.2e-10 40.0 0.0 4.1e-10 39.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PSC69043.1 - 8.6e-10 38.9 0.0 1.2e-09 38.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC69043.1 - 1.9e-05 24.6 0.0 3.1e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 PSC69043.1 - 0.0022 17.7 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PSC69043.1 - 0.072 13.8 0.0 0.42 11.3 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Rtf2 PF04641.12 PSC69044.1 - 4.2e-51 173.8 0.0 5.7e-51 173.4 0.0 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger zf-Nse PF11789.8 PSC69044.1 - 0.072 12.9 0.0 12 5.8 0.0 2.2 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 PSC69044.1 - 0.09 12.9 0.0 0.19 11.9 0.0 1.6 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Bestrophin PF01062.21 PSC69045.1 - 1.1e-13 51.2 0.3 5.9e-07 29.2 0.0 2.1 2 0 0 2 2 2 2 Bestrophin, RFP-TM, chloride channel F-box-like PF12937.7 PSC69046.1 - 1.5e-09 37.5 0.1 3e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PSC69046.1 - 1.2e-05 25.0 0.0 3e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 F-box domain Flavi_capsid PF01003.19 PSC69046.1 - 0.0097 15.7 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 Flavivirus capsid protein C PFK PF00365.20 PSC69047.1 - 6.8e-58 196.2 0.1 9e-58 195.8 0.1 1.1 1 0 0 1 1 1 1 Phosphofructokinase DUF2160 PF09928.9 PSC69047.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 Predicted small integral membrane protein (DUF2160) ArsA_ATPase PF02374.15 PSC69048.1 - 3.1e-137 456.8 0.0 2.4e-70 237.2 0.0 2.1 2 0 0 2 2 2 2 Anion-transporting ATPase CbiA PF01656.23 PSC69048.1 - 1.7e-22 79.9 0.2 4.2e-10 39.8 0.0 2.5 2 0 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 PSC69048.1 - 1.7e-15 57.4 0.5 4e-07 30.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain ParA PF10609.9 PSC69048.1 - 4.5e-14 52.5 12.4 1.2e-05 24.9 0.7 5.0 5 1 0 5 5 5 3 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 PSC69048.1 - 1.2e-08 34.8 1.3 0.0012 18.5 0.1 2.6 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain Fer4_NifH PF00142.18 PSC69048.1 - 1.5e-07 31.1 0.1 0.0065 16.0 0.0 2.4 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family CBP_BcsQ PF06564.12 PSC69048.1 - 7.1e-07 28.9 3.6 0.018 14.5 0.1 2.7 3 0 0 3 3 3 2 Cellulose biosynthesis protein BcsQ AAA_16 PF13191.6 PSC69048.1 - 5.3e-06 26.9 0.2 0.0038 17.6 0.0 2.9 2 0 0 2 2 2 1 AAA ATPase domain PhoH PF02562.16 PSC69048.1 - 5.9e-06 25.9 0.3 0.0045 16.5 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein AAA_25 PF13481.6 PSC69048.1 - 1.9e-05 24.4 3.4 0.026 14.1 0.1 3.2 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 PSC69048.1 - 3e-05 23.8 0.3 0.039 13.7 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 PSC69048.1 - 3.3e-05 23.7 0.2 0.13 12.0 0.0 3.3 3 1 0 3 3 3 2 AAA domain MeaB PF03308.16 PSC69048.1 - 0.00017 20.7 1.1 0.12 11.3 0.1 2.3 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB CLP1_P PF16575.5 PSC69048.1 - 0.00037 20.3 0.1 0.91 9.3 0.0 2.8 2 0 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop ATP_bind_1 PF03029.17 PSC69048.1 - 0.00057 19.7 1.4 0.28 11.0 0.1 2.4 2 0 0 2 2 2 2 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 PSC69048.1 - 0.00075 19.4 0.2 0.036 14.0 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase NACHT PF05729.12 PSC69048.1 - 0.00084 19.3 2.1 0.064 13.2 0.1 2.6 2 0 0 2 2 2 1 NACHT domain ATPase PF06745.13 PSC69048.1 - 0.00096 18.6 0.4 0.096 12.0 0.0 2.8 3 0 0 3 3 3 1 KaiC ResIII PF04851.15 PSC69048.1 - 0.0026 17.8 0.0 2 8.4 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit NB-ARC PF00931.22 PSC69048.1 - 0.005 16.1 0.4 0.099 11.8 0.0 2.2 2 0 0 2 2 2 1 NB-ARC domain AAA_7 PF12775.7 PSC69048.1 - 0.0054 16.3 0.4 1.6 8.2 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region RNA_helicase PF00910.22 PSC69048.1 - 0.0067 16.8 0.1 1.6 9.1 0.0 2.4 2 0 0 2 2 2 1 RNA helicase Zeta_toxin PF06414.12 PSC69048.1 - 0.012 14.9 0.5 2 7.7 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin DnaB_C PF03796.15 PSC69048.1 - 0.016 14.6 0.2 0.47 9.7 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain Med9 PF07544.13 PSC69048.1 - 0.017 15.2 0.1 0.017 15.2 0.1 3.1 4 0 0 4 4 2 0 RNA polymerase II transcription mediator complex subunit 9 DUF3763 PF12592.8 PSC69048.1 - 0.019 15.0 0.0 0.076 13.1 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3763) LpxK PF02606.14 PSC69048.1 - 0.037 13.1 3.2 1.8 7.6 0.2 2.3 2 0 0 2 2 2 0 Tetraacyldisaccharide-1-P 4'-kinase PIF1 PF05970.14 PSC69048.1 - 0.062 12.5 1.3 8 5.5 0.0 3.0 3 0 0 3 3 3 0 PIF1-like helicase Roc PF08477.13 PSC69048.1 - 0.066 13.4 0.2 2.9 8.1 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 PSC69048.1 - 0.074 13.3 0.5 2.3 8.5 0.0 2.6 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 PSC69048.1 - 0.11 12.0 0.1 7.5 5.9 0.0 2.5 2 0 0 2 2 2 0 Chromatin associated protein KTI12 Thymidylate_kin PF02223.17 PSC69048.1 - 0.12 12.1 0.1 7.3 6.2 0.0 2.6 2 0 0 2 2 2 0 Thymidylate kinase APS_kinase PF01583.20 PSC69048.1 - 0.14 12.1 0.5 12 5.7 0.1 2.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA PF00004.29 PSC69048.1 - 0.14 12.5 1.8 3.4 8.1 0.1 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 PSC69048.1 - 0.15 12.6 1.9 2.7 8.5 0.0 3.0 3 0 0 3 3 2 0 AAA domain T2SSE PF00437.20 PSC69048.1 - 0.16 11.0 2.2 2.4 7.1 0.0 3.2 3 1 0 3 3 3 0 Type II/IV secretion system protein AAA_30 PF13604.6 PSC69048.1 - 0.21 11.3 8.3 2.7 7.7 0.3 3.2 4 0 0 4 4 3 0 AAA domain CTP_synth_N PF06418.14 PSC69048.1 - 0.75 9.0 2.1 21 4.3 0.1 2.7 3 0 0 3 3 3 0 CTP synthase N-terminus AAA_33 PF13671.6 PSC69048.1 - 1.6 8.9 4.1 12 6.0 0.1 2.9 3 0 0 3 3 3 0 AAA domain MipZ PF09140.11 PSC69048.1 - 1.7 7.9 3.6 18 4.5 0.4 2.6 2 0 0 2 2 2 0 ATPase MipZ Pro_isomerase PF00160.21 PSC69049.1 - 1.3e-44 152.2 0.0 1.5e-44 152.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD CSN8_PSD8_EIF3K PF10075.9 PSC69050.1 - 7.3e-25 87.6 1.6 2.1e-24 86.1 0.0 2.1 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family Radical_SAM PF04055.21 PSC69050.1 - 1.5e-12 48.3 0.0 4.4e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_14 PF13394.6 PSC69050.1 - 0.0019 18.3 0.0 0.0019 18.3 0.0 2.2 2 0 0 2 2 1 1 4Fe-4S single cluster domain DDHD PF02862.17 PSC69050.1 - 0.013 15.7 0.6 0.02 15.1 0.6 1.3 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 PSC69050.1 - 0.077 11.8 10.8 0.14 10.9 10.8 1.3 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 PSC69050.1 - 0.078 13.0 27.2 0.12 12.4 27.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit hDGE_amylase PF14701.6 PSC69050.1 - 0.17 10.9 4.6 0.32 10.0 4.6 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain SLC12 PF03522.15 PSC69050.1 - 0.25 10.3 14.9 0.43 9.5 14.9 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Spem1 PF15670.5 PSC69050.1 - 0.44 10.1 10.5 0.7 9.4 10.5 1.2 1 0 0 1 1 1 0 Spermatid maturation protein 1 PTPRCAP PF15713.5 PSC69050.1 - 0.46 10.8 15.7 1.1 9.5 15.7 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated NARP1 PF12569.8 PSC69050.1 - 0.94 8.3 11.0 1.3 7.8 11.0 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Ndc1_Nup PF09531.10 PSC69050.1 - 1.2 7.8 5.1 2 7.0 5.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM60A PF15396.6 PSC69050.1 - 1.2 9.0 5.6 1.9 8.4 5.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A FancD2 PF14631.6 PSC69050.1 - 1.3 6.4 5.5 1.7 5.9 5.5 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease RR_TM4-6 PF06459.12 PSC69050.1 - 1.5 8.6 11.6 2.3 8.0 11.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 PSC69050.1 - 1.5 8.8 4.8 2.7 8.0 4.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CobT PF06213.12 PSC69050.1 - 2.9 7.2 21.5 5.2 6.4 21.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF3464 PF11947.8 PSC69050.1 - 3 7.6 6.8 8.6 6.1 6.8 1.8 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 KAAG1 PF15354.6 PSC69050.1 - 3.2 8.3 6.9 13 6.4 0.0 3.7 3 0 0 3 3 3 0 Kidney-associated antigen 1 eIF-3_zeta PF05091.12 PSC69050.1 - 3.4 6.5 17.1 4.7 6.1 17.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PhoQ_Sensor PF08918.10 PSC69050.1 - 4.9 7.0 4.7 8.5 6.2 4.7 1.3 1 0 0 1 1 1 0 PhoQ Sensor DUF4407 PF14362.6 PSC69050.1 - 6.9 5.9 17.5 13 5.0 17.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MMR1 PF08505.10 PSC69050.1 - 9.1 6.5 14.2 14 5.9 14.2 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein KDZ PF18758.1 PSC69051.1 - 3.5e-15 56.2 1.9 4.8e-15 55.8 1.9 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF2269 PF10027.9 PSC69051.1 - 0.0032 17.5 2.5 0.0038 17.3 0.6 1.8 1 1 1 2 2 2 1 Predicted integral membrane protein (DUF2269) Proteasome PF00227.26 PSC69052.1 - 1.8e-49 167.8 0.0 2.1e-49 167.6 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Glyco_hydro_2_C PF02836.17 PSC69053.1 - 1.3e-96 323.3 0.0 1.7e-96 322.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, TIM barrel domain Bgal_small_N PF02929.17 PSC69053.1 - 2.8e-67 226.9 0.0 4.4e-67 226.2 0.0 1.3 1 0 0 1 1 1 1 Beta galactosidase small chain Glyco_hydro_2_N PF02837.18 PSC69053.1 - 9.6e-46 155.8 0.0 1.6e-45 155.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 2, sugar binding domain CAP PF00188.26 PSC69053.1 - 9e-15 55.6 4.6 2.3e-14 54.3 4.6 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF4981 PF16353.5 PSC69053.1 - 1.7e-09 38.0 0.0 7.9e-09 35.9 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function(DUF4981) Glyco_hydro_2 PF00703.21 PSC69053.1 - 0.016 15.9 0.0 0.055 14.1 0.0 2.0 1 1 0 1 1 1 0 Glycosyl hydrolases family 2 IF-2B PF01008.17 PSC69054.1 - 4.7e-73 245.8 0.0 6.3e-73 245.4 0.0 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family ImpA_N PF06812.12 PSC69054.1 - 0.1 12.7 0.6 9.8 6.3 0.0 2.3 1 1 1 2 2 2 0 ImpA, N-terminal, type VI secretion system Phage_lysozyme PF00959.19 PSC69054.1 - 0.11 13.0 0.0 0.39 11.2 0.0 1.9 2 0 0 2 2 2 0 Phage lysozyme SAM_2 PF07647.17 PSC69055.1 - 1.4e-06 28.3 0.0 1.9e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PSC69055.1 - 1.8e-06 28.3 0.0 2.4e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 PSC69055.1 - 0.0021 18.0 0.0 0.0035 17.3 0.0 1.2 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain SAM_Ste50p PF09235.10 PSC69055.1 - 0.12 12.7 0.0 0.16 12.3 0.0 1.2 1 0 0 1 1 1 0 Ste50p, sterile alpha motif HARE-HTH PF05066.13 PSC69056.1 - 6.5e-23 80.9 0.0 0.00056 20.2 0.0 5.8 5 0 0 5 5 5 5 HB1, ASXL, restriction endonuclease HTH domain WAC_Acf1_DNA_bd PF10537.9 PSC69056.1 - 2.1e-21 76.3 0.0 2.1e-21 76.3 0.0 3.0 2 0 0 2 2 2 1 ATP-utilising chromatin assembly and remodelling N-terminal WSD PF15613.6 PSC69056.1 - 4.8e-10 39.8 1.3 4.8e-10 39.8 1.3 5.3 4 3 0 4 4 4 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif DDT PF02791.17 PSC69056.1 - 0.0039 17.5 0.0 0.014 15.7 0.0 2.0 1 0 0 1 1 1 1 DDT domain WHIM1 PF15612.6 PSC69056.1 - 0.19 11.3 0.1 0.5 10.0 0.1 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 LepB_N PF18640.1 PSC69056.1 - 0.33 10.5 1.5 26 4.3 0.1 2.8 3 0 0 3 3 3 0 LepB N-terminal domain EPO_TPO PF00758.18 PSC69056.1 - 1 9.4 6.7 16 5.5 0.1 4.5 5 0 0 5 5 5 0 Erythropoietin/thrombopoietin Lipase_3 PF01764.25 PSC69057.1 - 5.4e-58 194.9 0.0 4.6e-28 97.9 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) zf-RING_2 PF13639.6 PSC69057.1 - 2.7e-06 27.6 8.2 1.2e-05 25.6 8.2 2.2 1 0 0 1 1 1 1 Ring finger domain DUF2974 PF11187.8 PSC69057.1 - 5.8e-06 26.0 0.0 0.45 10.0 0.0 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF2974) zf-C3HC4 PF00097.25 PSC69057.1 - 0.00027 20.7 4.6 0.00067 19.5 4.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Hydrolase_4 PF12146.8 PSC69057.1 - 0.015 14.5 0.0 3 7.1 0.0 2.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 zf-RING_11 PF17123.5 PSC69057.1 - 0.056 13.2 2.9 0.15 11.8 2.9 1.8 1 0 0 1 1 1 0 RING-like zinc finger Thioesterase PF00975.20 PSC69057.1 - 0.12 12.5 0.1 13 5.8 0.0 2.4 2 0 0 2 2 2 0 Thioesterase domain zf-C3HC4_2 PF13923.6 PSC69057.1 - 0.24 11.3 6.7 0.99 9.3 6.7 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC69057.1 - 0.49 10.4 10.0 0.093 12.7 5.1 2.3 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 PSC69057.1 - 3.4 7.6 12.5 0.2 11.6 6.8 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Lipase_3 PF01764.25 PSC69058.1 - 5.1e-58 195.0 0.0 4.5e-28 97.9 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) zf-RING_2 PF13639.6 PSC69058.1 - 2.6e-06 27.7 8.2 1.1e-05 25.6 8.2 2.2 1 0 0 1 1 1 1 Ring finger domain DUF2974 PF11187.8 PSC69058.1 - 5.4e-06 26.1 0.0 0.44 10.0 0.0 3.6 4 0 0 4 4 4 2 Protein of unknown function (DUF2974) zf-C3HC4 PF00097.25 PSC69058.1 - 0.00026 20.8 4.6 0.00066 19.5 4.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Hydrolase_4 PF12146.8 PSC69058.1 - 0.015 14.6 0.0 2.9 7.1 0.0 2.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 zf-RING_11 PF17123.5 PSC69058.1 - 0.055 13.2 2.9 0.15 11.8 2.9 1.8 1 0 0 1 1 1 0 RING-like zinc finger Thioesterase PF00975.20 PSC69058.1 - 0.12 12.4 0.1 13 5.8 0.0 2.4 2 0 0 2 2 2 0 Thioesterase domain zf-C3HC4_2 PF13923.6 PSC69058.1 - 0.23 11.4 6.6 0.94 9.4 6.6 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC69058.1 - 0.47 10.4 10.0 0.091 12.7 5.1 2.3 2 0 0 2 2 2 0 zinc-RING finger domain Prok-RING_4 PF14447.6 PSC69058.1 - 3.3 7.7 12.5 0.19 11.6 6.8 1.9 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Aminotran_1_2 PF00155.21 PSC69059.1 - 5.3e-89 298.9 0.0 6.8e-89 298.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1543 PF07566.12 PSC69059.1 - 0.0045 16.7 0.4 0.081 12.7 0.1 2.7 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1543) RNF220 PF15926.5 PSC69059.1 - 0.064 12.9 0.2 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 Aminotran_1_2 PF00155.21 PSC69060.1 - 6.1e-89 298.7 0.0 7.8e-89 298.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF1543 PF07566.12 PSC69060.1 - 0.0053 16.5 0.4 0.087 12.6 0.1 2.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1543) RNF220 PF15926.5 PSC69060.1 - 0.071 12.7 0.1 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 E3 ubiquitin-protein ligase RNF220 Glyoxalase PF00903.25 PSC69061.1 - 2.1e-08 34.4 0.0 3e-05 24.2 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 PSC69061.1 - 4e-06 27.1 0.0 0.0079 16.5 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 PSC69061.1 - 0.00078 19.6 0.1 0.0048 17.1 0.0 2.2 2 1 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal DUF1664 PF07889.12 PSC69062.1 - 0.22 11.6 0.1 0.22 11.6 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Rick_17kDa_Anti PF05433.15 PSC69062.1 - 4 7.4 7.9 3.9 7.4 1.2 2.3 2 0 0 2 2 2 0 Glycine zipper 2TM domain DHHC PF01529.20 PSC69063.1 - 1.2e-29 103.1 2.0 2.1e-29 102.3 2.0 1.4 1 0 0 1 1 1 1 DHHC palmitoyltransferase Amino_oxidase PF01593.24 PSC69064.1 - 2.6e-21 76.5 0.0 1.9e-19 70.3 0.0 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PSC69064.1 - 1.3e-11 44.6 0.3 3.5e-11 43.2 0.3 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 PSC69064.1 - 7.4e-07 28.7 0.2 2.9e-05 23.5 0.3 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PSC69064.1 - 9.1e-07 28.8 3.1 3.8e-06 26.7 3.1 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PSC69064.1 - 6.4e-06 25.5 2.5 0.01 14.9 0.3 2.3 2 0 0 2 2 2 2 FAD binding domain HI0933_like PF03486.14 PSC69064.1 - 0.00028 19.7 0.3 0.0089 14.8 0.2 2.1 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_3 PF01494.19 PSC69064.1 - 0.0029 16.9 0.3 0.044 13.0 0.1 2.6 3 0 0 3 3 3 1 FAD binding domain FAD_oxidored PF12831.7 PSC69064.1 - 0.003 17.0 0.4 0.0054 16.1 0.1 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.22 PSC69064.1 - 0.0069 15.5 0.2 0.0069 15.5 0.2 1.5 2 0 0 2 2 2 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 PSC69064.1 - 0.011 16.1 0.0 0.038 14.4 0.0 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding AlaDh_PNT_C PF01262.21 PSC69064.1 - 0.011 15.0 2.1 0.016 14.5 0.5 2.0 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 PSC69064.1 - 0.069 13.0 0.2 0.15 11.9 0.2 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pyr_redox PF00070.27 PSC69064.1 - 0.08 13.5 0.6 0.37 11.4 0.2 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 PSC69064.1 - 0.29 9.9 0.0 9.6 4.9 0.0 2.2 2 0 0 2 2 2 0 MCRA family MARVEL PF01284.23 PSC69065.1 - 0.0097 15.9 10.7 0.017 15.2 10.7 1.3 1 0 0 1 1 1 1 Membrane-associating domain HRG PF16954.5 PSC69065.1 - 0.046 14.1 2.5 0.046 14.1 2.5 2.0 3 0 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Maf1 PF09174.10 PSC69066.1 - 2.3e-55 187.4 0.1 4e-55 186.6 0.0 1.4 2 0 0 2 2 2 1 Maf1 regulator Pro_isomerase PF00160.21 PSC69067.1 - 1.2e-06 28.8 0.0 3.1e-06 27.6 0.0 1.6 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF2076 PF09849.9 PSC69067.1 - 1.8 8.6 10.5 3.4 7.6 10.5 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) UCH PF00443.29 PSC69068.1 - 2.1e-36 125.7 0.0 3.8e-36 124.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Bestrophin PF01062.21 PSC69068.1 - 4.6e-32 111.6 6.1 6.9e-32 111.0 6.1 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel UCH_1 PF13423.6 PSC69068.1 - 4.5e-13 49.5 0.0 5.1e-07 29.6 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.20 PSC69068.1 - 0.0001 22.0 18.9 0.0093 15.8 6.2 4.0 3 0 0 3 3 3 2 Ubiquitin interaction motif UCH PF00443.29 PSC69069.1 - 2.1e-36 125.7 0.0 3.8e-36 124.9 0.0 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Bestrophin PF01062.21 PSC69069.1 - 3.1e-32 112.2 6.4 4.6e-32 111.6 6.4 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel UCH_1 PF13423.6 PSC69069.1 - 4.5e-13 49.5 0.0 5.1e-07 29.6 0.0 3.2 3 0 0 3 3 3 3 Ubiquitin carboxyl-terminal hydrolase UIM PF02809.20 PSC69069.1 - 0.0001 22.0 18.9 0.0093 15.8 6.2 4.0 3 0 0 3 3 3 2 Ubiquitin interaction motif Fasciclin PF02469.22 PSC69070.1 - 1.4e-47 161.1 0.3 2.2e-25 89.3 0.0 2.2 2 0 0 2 2 2 2 Fasciclin domain Cpn60_TCP1 PF00118.24 PSC69071.1 - 3.7e-152 507.4 11.5 4.2e-152 507.2 11.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family zf-CCCH PF00642.24 PSC69072.1 - 1.3e-36 123.8 65.2 9.2e-10 38.2 2.8 6.8 7 0 0 7 7 7 6 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PSC69072.1 - 3.7e-23 80.8 56.0 4e-05 23.3 0.9 7.4 7 0 0 7 7 7 6 CCCH-type zinc finger VASt PF16016.5 PSC69072.1 - 2.6e-22 79.9 0.0 3.7e-22 79.4 0.0 1.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain zf_CCCH_4 PF18345.1 PSC69072.1 - 2.6e-19 68.6 70.8 2.7e-06 27.2 4.4 6.6 6 0 0 6 6 6 6 Zinc finger domain U-box PF04564.15 PSC69072.1 - 2.6e-18 66.0 0.0 5.7e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 U-box domain zf-Nse PF11789.8 PSC69072.1 - 1.2e-10 41.1 0.7 0.00028 20.6 0.0 2.5 2 0 0 2 2 2 2 Zinc-finger of the MIZ type in Nse subunit zf-CCCH_2 PF14608.6 PSC69072.1 - 5.9e-08 32.9 42.6 0.012 16.0 2.8 7.0 7 0 0 7 7 7 5 RNA-binding, Nab2-type zinc finger zf-NOSIP PF15906.5 PSC69072.1 - 2.6e-07 30.7 0.3 0.0043 17.1 0.1 2.5 2 0 0 2 2 2 2 Zinc-finger of nitric oxide synthase-interacting protein Torus PF16131.5 PSC69072.1 - 0.0013 19.4 43.1 0.018 15.7 1.2 6.4 4 2 2 6 6 6 4 Torus domain zf-CCCH_3 PF15663.5 PSC69072.1 - 0.0029 17.8 0.1 0.0029 17.8 0.1 4.4 4 0 0 4 4 4 2 Zinc-finger containing family HA2 PF04408.23 PSC69072.1 - 0.021 15.1 0.0 14 6.0 0.0 2.6 2 0 0 2 2 2 0 Helicase associated domain (HA2) PPR_2 PF13041.6 PSC69073.1 - 2.2e-31 107.8 0.0 6.8e-09 35.8 0.0 7.7 7 2 3 10 10 10 5 PPR repeat family DNA_methylase PF00145.17 PSC69073.1 - 3.9e-31 108.6 0.0 7.9e-31 107.6 0.0 1.5 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase PPR_3 PF13812.6 PSC69073.1 - 2.4e-24 85.2 0.0 1.7e-07 31.2 0.0 6.9 5 2 2 7 7 7 4 Pentatricopeptide repeat domain PPR_long PF17177.4 PSC69073.1 - 7.3e-17 61.4 1.2 8.9e-06 25.2 0.0 3.9 2 1 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 PSC69073.1 - 2.2e-12 46.3 0.0 0.0019 18.3 0.0 7.1 8 0 0 8 8 8 3 PPR repeat PPR_1 PF12854.7 PSC69073.1 - 1.3e-09 37.5 0.0 0.71 9.6 0.0 7.1 8 0 0 8 8 8 3 PPR repeat DOT1 PF08123.13 PSC69073.1 - 0.26 10.8 0.0 0.44 10.0 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 TRAP_beta PF05753.14 PSC69075.1 - 7.4e-23 80.9 0.0 9.2e-23 80.5 0.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) DUF11 PF01345.18 PSC69075.1 - 2.9e-06 27.5 0.0 5.2e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF11 DIM PF08194.12 PSC69075.1 - 0.082 13.1 0.3 0.18 12.0 0.3 1.6 1 0 0 1 1 1 0 DIM protein CARDB PF07705.11 PSC69075.1 - 0.085 13.1 0.0 0.18 12.1 0.0 1.7 1 1 0 1 1 1 0 CARDB PgaD PF13994.6 PSC69075.1 - 0.14 12.2 0.1 0.23 11.5 0.1 1.3 1 0 0 1 1 1 0 PgaD-like protein ABC_membrane PF00664.23 PSC69076.1 - 7.6e-54 183.2 2.2 1e-53 182.8 2.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PSC69076.1 - 6.1e-19 68.9 0.0 3.2e-18 66.6 0.0 2.1 1 1 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PSC69076.1 - 1.1e-05 25.0 0.0 0.00035 20.1 0.0 1.9 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 PSC69076.1 - 0.0034 17.7 0.0 0.015 15.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PSC69076.1 - 0.038 14.4 6.9 0.022 15.1 2.7 2.7 2 1 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 PSC69076.1 - 0.06 13.4 0.1 0.1 12.7 0.1 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain ABC_ATPase PF09818.9 PSC69076.1 - 0.074 11.8 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_29 PF13555.6 PSC69076.1 - 0.075 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 PSC69076.1 - 0.21 11.8 3.3 0.66 10.2 0.5 3.1 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Myb_DNA-binding PF00249.31 PSC69078.1 - 6e-09 35.9 0.0 1.3e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain ZZ PF00569.17 PSC69078.1 - 6.1e-08 32.4 6.2 1.1e-07 31.5 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 PSC69078.1 - 0.019 15.3 0.0 0.048 14.0 0.0 1.7 1 0 0 1 1 1 0 SWIRM domain Pectate_lyase_3 PF12708.7 PSC69079.1 - 8.9e-22 78.0 6.1 3.7e-20 72.7 0.4 2.7 2 1 1 3 3 3 3 Pectate lyase superfamily protein Beta_helix PF13229.6 PSC69079.1 - 0.015 15.1 2.6 0.046 13.6 2.6 1.5 1 1 0 1 1 1 0 Right handed beta helix region End_N_terminal PF12218.8 PSC69079.1 - 0.024 14.3 0.4 0.054 13.2 0.4 1.6 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase NosD PF05048.13 PSC69079.1 - 0.15 11.3 2.3 0.33 10.2 2.3 1.5 1 1 0 1 1 1 0 Periplasmic copper-binding protein (NosD) UAA PF08449.11 PSC69080.1 - 2.1e-55 188.1 3.6 3.9e-55 187.2 3.6 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 PSC69080.1 - 7.5e-05 22.9 29.7 0.00011 22.4 15.7 2.9 2 1 1 3 3 3 2 EamA-like transporter family TPT PF03151.16 PSC69080.1 - 0.00034 20.1 3.4 0.0013 18.2 0.4 2.2 2 0 0 2 2 2 1 Triose-phosphate Transporter family UAA PF08449.11 PSC69081.1 - 7.3e-54 183.0 2.1 1.4e-53 182.1 2.1 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 PSC69081.1 - 7e-06 26.3 25.4 0.00011 22.4 15.7 2.4 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 PSC69081.1 - 0.00029 20.3 3.1 0.0011 18.3 0.3 2.1 2 0 0 2 2 2 1 Triose-phosphate Transporter family DUF2070 PF09843.9 PSC69081.1 - 4.2 5.6 14.4 0.21 9.8 7.5 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) RhoGAP PF00620.27 PSC69082.1 - 3.9e-13 49.5 0.0 5.5e-13 49.0 0.0 1.2 1 0 0 1 1 1 1 RhoGAP domain Inositol_P PF00459.25 PSC69083.1 - 1.4e-71 241.2 0.0 1.6e-71 241.0 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family CobN-Mg_chel PF02514.16 PSC69084.1 - 0 1139.2 0.1 0 1129.8 0.0 2.3 3 0 0 3 3 3 1 CobN/Magnesium Chelatase DUF3479 PF11965.8 PSC69084.1 - 2.3e-47 161.1 0.1 2.3e-47 161.1 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3479) bZIP_1 PF00170.21 PSC69084.1 - 4.4e-12 45.9 5.2 4.4e-12 45.9 5.2 2.8 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.15 PSC69084.1 - 5.1e-09 36.1 6.1 2.7e-08 33.8 6.1 2.3 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 PSC69084.1 - 0.013 16.0 16.7 0.066 13.7 2.6 2.9 2 0 0 2 2 2 0 bZIP Maf transcription factor bZIP_1 PF00170.21 PSC69085.1 - 1e-12 47.9 5.2 1e-12 47.9 5.2 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 PSC69085.1 - 6.4e-09 35.8 6.1 6.4e-09 35.8 6.1 2.6 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 PSC69085.1 - 0.013 16.0 2.4 0.013 16.0 2.4 3.2 2 1 0 2 2 2 0 bZIP Maf transcription factor Shugoshin_N PF07558.11 PSC69085.1 - 0.084 12.8 0.5 0.18 11.7 0.5 1.5 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region HAUS6_N PF14661.6 PSC69085.1 - 0.36 10.4 11.2 2.3 7.7 0.4 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus SET PF00856.28 PSC69085.1 - 0.5 10.7 5.5 0.18 12.2 1.2 2.1 2 0 0 2 2 2 0 SET domain EPL1 PF10513.9 PSC69085.1 - 1.5 9.1 7.2 0.37 11.2 2.6 2.0 2 0 0 2 2 2 0 Enhancer of polycomb-like Pinin_SDK_memA PF04696.13 PSC69085.1 - 2.3 8.3 20.8 6.4 6.9 9.8 2.5 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region DDHD PF02862.17 PSC69085.1 - 3.4 7.8 9.9 0.19 11.8 2.9 2.1 2 0 0 2 2 2 0 DDHD domain DUF572 PF04502.13 PSC69085.1 - 6.9 6.2 11.5 4.9 6.7 2.5 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF572) Aldedh PF00171.22 PSC69086.1 - 4.2e-147 490.4 2.2 4.6e-84 282.5 0.0 3.2 2 1 1 3 3 3 3 Aldehyde dehydrogenase family ABC_tran PF00005.27 PSC69086.1 - 1.7e-14 54.5 0.0 8.2e-14 52.3 0.0 2.2 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 PSC69086.1 - 8.8e-10 38.9 0.0 0.00081 19.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TPT PF03151.16 PSC69086.1 - 2.2e-09 37.1 7.3 3.2e-09 36.6 7.3 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family AAA_25 PF13481.6 PSC69086.1 - 5e-05 23.0 0.4 0.0069 16.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 PSC69086.1 - 0.0031 17.2 0.1 0.014 15.1 0.1 2.1 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 PSC69086.1 - 0.045 14.2 0.1 0.076 13.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 PSC69086.1 - 0.083 12.3 0.2 8.9 5.7 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 PSC69086.1 - 0.13 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 PSC69086.1 - 0.15 12.4 0.1 0.53 10.7 0.1 1.9 1 0 0 1 1 1 0 AAA ATPase domain AAA_15 PF13175.6 PSC69086.1 - 0.2 11.3 0.0 0.3 10.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain NUDIX PF00293.28 PSC69087.1 - 2.3e-19 69.7 0.0 3.1e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain DNase-RNase PF02577.14 PSC69088.1 - 1e-16 60.8 0.0 1.6e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Bifunctional nuclease VHL PF01847.16 PSC69088.1 - 1.2e-11 44.4 0.1 1.9e-11 43.7 0.1 1.3 1 0 0 1 1 1 1 VHL beta domain UCH PF00443.29 PSC69089.1 - 3.4e-18 66.1 0.0 5.8e-18 65.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PSC69089.1 - 1.7e-05 24.6 0.1 0.00058 19.6 0.1 2.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TPR_6 PF13174.6 PSC69090.1 - 0.14 12.9 0.0 0.69 10.7 0.0 1.9 1 1 1 2 2 2 0 Tetratricopeptide repeat WD40 PF00400.32 PSC69091.1 - 1.1e-21 76.8 0.9 3.8e-05 24.4 0.0 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Katanin_con80 PF13925.6 PSC69091.1 - 6.4e-15 55.5 0.0 2.3e-14 53.8 0.0 1.8 2 0 0 2 2 2 1 con80 domain of Katanin ANAPC4_WD40 PF12894.7 PSC69091.1 - 1.9e-06 28.1 0.1 0.73 10.2 0.1 5.1 2 1 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PSC69091.1 - 0.014 14.1 0.0 7.8 5.0 0.0 2.8 2 1 1 3 3 3 0 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 PSC69091.1 - 0.088 11.5 0.0 4.6 5.9 0.0 2.5 1 1 1 2 2 2 0 Nup133 N terminal like Polysacc_deac_1 PF01522.21 PSC69092.1 - 4.5e-11 42.7 0.0 1.2e-10 41.4 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide deacetylase Glyco_hydro_14 PF01373.17 PSC69095.1 - 6.3e-97 325.1 0.0 8.5e-76 255.5 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 14 Glyco_hydro_35 PF01301.19 PSC69095.1 - 0.006 16.2 0.1 0.011 15.4 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Spt20 PF12090.8 PSC69095.1 - 3.1 7.3 10.9 5.4 6.5 10.9 1.3 1 0 0 1 1 1 0 Spt20 family Glyco_hydro_14 PF01373.17 PSC69096.1 - 3.6e-97 325.9 0.0 6.2e-76 255.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl hydrolase family 14 Glyco_hydro_35 PF01301.19 PSC69096.1 - 0.0048 16.6 0.1 0.0087 15.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 35 Spt20 PF12090.8 PSC69096.1 - 2.5 7.6 10.9 4.5 6.8 10.9 1.3 1 0 0 1 1 1 0 Spt20 family VTC PF09359.10 PSC69098.1 - 6.9e-48 163.4 0.0 9.9e-48 162.9 0.0 1.2 1 0 0 1 1 1 1 VTC domain DUF202 PF02656.15 PSC69098.1 - 7.4e-08 32.7 0.5 2.1e-07 31.3 0.5 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF202) FAD_binding_3 PF01494.19 PSC69099.1 - 8.8e-18 64.7 2.4 1.4e-16 60.7 2.4 2.2 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 PSC69099.1 - 1.9e-08 33.8 1.0 3.1e-08 33.1 1.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 PSC69099.1 - 6.5e-05 22.3 1.0 0.00017 20.9 1.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PSC69099.1 - 6.6e-05 23.1 1.4 6.6e-05 23.1 1.4 2.6 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 PSC69099.1 - 0.00016 20.9 3.7 0.00016 20.9 3.7 1.8 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 PSC69099.1 - 0.00028 19.7 3.6 0.00028 19.7 1.9 1.7 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 PSC69099.1 - 0.00041 19.7 1.1 0.00061 19.1 1.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PSC69099.1 - 0.00084 18.6 0.3 0.0015 17.8 0.3 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 PSC69099.1 - 0.0011 18.4 4.6 0.002 17.6 4.6 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO PF01266.24 PSC69099.1 - 0.0019 17.8 4.3 0.003 17.2 4.3 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 PSC69099.1 - 0.0035 16.5 3.3 0.0052 15.9 3.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Amino_oxidase PF01593.24 PSC69099.1 - 0.013 14.8 2.6 0.45 9.7 1.5 2.6 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 PSC69099.1 - 0.043 14.4 0.9 0.097 13.2 0.4 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 PSC69099.1 - 0.21 10.9 1.3 0.43 9.8 1.3 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Trp_halogenase PF04820.14 PSC69099.1 - 0.56 9.0 2.7 0.41 9.4 1.2 1.5 2 0 0 2 2 2 0 Tryptophan halogenase GTP_EFTU PF00009.27 PSC69100.1 - 4.8e-56 189.4 0.0 7.4e-56 188.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 PSC69100.1 - 1.4e-13 50.7 0.0 3.6e-13 49.4 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PSC69100.1 - 3.1e-11 43.5 0.0 1.3e-10 41.5 0.0 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 PSC69100.1 - 4.9e-10 39.4 0.0 9.9e-10 38.4 0.0 1.4 1 0 0 1 1 1 1 Elongation Factor G, domain II Pkinase PF00069.25 PSC69101.1 - 3.1e-22 79.2 0.0 8.6e-15 54.8 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC69101.1 - 2.1e-11 43.6 0.0 3.3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PSC69101.1 - 0.021 13.6 0.0 0.034 12.9 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 PSC69101.1 - 0.061 13.2 0.0 0.061 13.2 0.0 2.5 3 1 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 PSC69101.1 - 0.085 12.2 0.6 0.3 10.4 0.1 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PSC69101.1 - 0.21 11.2 0.0 0.37 10.3 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Arm PF00514.23 PSC69102.1 - 1.1e-18 66.6 9.7 2.5e-07 30.5 0.2 5.5 4 0 0 4 4 4 4 Armadillo/beta-catenin-like repeat UCH PF00443.29 PSC69102.1 - 1.8e-14 53.9 0.0 2.7e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase HEAT PF02985.22 PSC69102.1 - 0.0029 17.7 4.9 0.025 14.8 0.1 4.5 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.6 PSC69102.1 - 0.006 17.1 1.7 0.006 17.1 1.7 9.2 9 1 1 10 10 10 2 HEAT-like repeat C1_1 PF00130.22 PSC69102.1 - 0.086 12.7 0.5 0.23 11.4 0.5 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) UCH_1 PF13423.6 PSC69102.1 - 0.17 11.4 0.0 1.1 8.8 0.0 2.3 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase PHD_2 PF13831.6 PSC69102.1 - 0.62 9.7 2.4 2.4 7.8 2.4 2.0 1 0 0 1 1 1 0 PHD-finger ABC_tran PF00005.27 PSC69103.1 - 9.9e-22 77.9 0.0 2.2e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 PSC69103.1 - 4e-19 68.9 14.3 5.7e-19 68.4 14.3 1.2 1 0 0 1 1 1 1 ABC-2 type transporter AAA_21 PF13304.6 PSC69103.1 - 0.0019 18.1 0.5 0.45 10.3 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system zf-CCCH PF00642.24 PSC69103.1 - 0.0084 16.0 0.7 0.018 14.9 0.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AAA_25 PF13481.6 PSC69103.1 - 0.014 15.0 3.9 0.07 12.7 0.2 3.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 PSC69103.1 - 0.048 13.6 0.1 0.11 12.4 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase zf-CCCH_4 PF18044.1 PSC69103.1 - 0.063 13.1 2.1 0.12 12.2 2.1 1.5 1 0 0 1 1 1 0 CCCH-type zinc finger AAA_29 PF13555.6 PSC69103.1 - 0.082 12.7 0.7 0.24 11.2 0.7 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain zf-CCCH_2 PF14608.6 PSC69103.1 - 0.12 12.8 1.3 0.23 12.0 1.3 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 PSC69103.1 - 0.14 12.2 3.3 0.3 11.2 3.3 1.6 1 0 0 1 1 1 0 Zinc finger domain Ribosomal_S26e PF01283.19 PSC69104.1 - 5.8e-50 168.3 6.9 6.1e-50 168.2 6.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Polysacc_deac_1 PF01522.21 PSC69105.1 - 7.2e-20 71.1 0.0 7.9e-08 32.2 0.0 3.6 3 0 0 3 3 3 3 Polysaccharide deacetylase DUF2334 PF10096.9 PSC69105.1 - 0.019 14.6 0.0 1.5 8.4 0.0 2.9 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2334) DUF4381 PF14316.6 PSC69105.1 - 0.1 12.8 3.7 2.9 8.1 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) SNARE PF05739.19 PSC69106.1 - 5.5e-14 51.9 2.6 5.6e-14 51.9 0.8 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 PSC69106.1 - 0.0012 18.6 14.6 0.017 14.8 0.4 2.6 3 0 0 3 3 3 2 Syntaxin Orf78 PF06024.12 PSC69106.1 - 0.12 12.7 0.5 0.21 11.9 0.5 1.4 1 0 0 1 1 1 0 Orf78 (ac78) MCPsignal PF00015.21 PSC69106.1 - 0.22 11.4 4.0 0.12 12.2 0.5 2.2 2 1 1 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Synaptobrevin PF00957.21 PSC69106.1 - 5.7 6.8 8.9 0.99 9.2 4.1 2.1 2 0 0 2 2 2 0 Synaptobrevin AMP-binding PF00501.28 PSC69107.1 - 1.5e-95 320.3 0.0 2e-95 319.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PSC69107.1 - 0.0027 18.6 0.1 0.015 16.2 0.0 2.2 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain DivIC PF04977.15 PSC69110.1 - 0.02 14.7 0.9 0.02 14.7 0.9 1.9 2 0 0 2 2 2 0 Septum formation initiator DUF4140 PF13600.6 PSC69110.1 - 0.038 14.4 2.3 0.12 12.8 1.0 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HisKA_3 PF07730.13 PSC69110.1 - 0.055 14.0 6.1 1.8 9.2 0.0 3.0 3 0 0 3 3 3 0 Histidine kinase FadA PF09403.10 PSC69110.1 - 0.066 13.7 7.2 1.4 9.4 4.6 2.2 2 0 0 2 2 2 0 Adhesion protein FadA DUF3138 PF11336.8 PSC69110.1 - 0.098 11.3 3.0 0.16 10.6 3.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) bZIP_Maf PF03131.17 PSC69110.1 - 1.2 9.7 6.7 0.36 11.4 2.8 2.0 2 0 0 2 2 2 0 bZIP Maf transcription factor Spc7 PF08317.11 PSC69110.1 - 1.2 7.9 4.9 1.1 8.1 3.7 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein APG6_N PF17675.1 PSC69110.1 - 1.5 9.4 7.3 2.4 8.7 4.1 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF3311 PF11755.8 PSC69111.1 - 0.0049 16.8 2.1 0.0049 16.8 2.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3311) Myb_DNA-bind_6 PF13921.6 PSC69112.1 - 6.4e-08 32.7 0.6 1.4e-07 31.6 0.6 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 PSC69112.1 - 1.3e-06 28.4 0.4 3.1e-06 27.3 0.4 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 PSC69112.1 - 0.019 15.1 0.2 0.038 14.2 0.2 1.4 1 0 0 1 1 1 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_5 PF13873.6 PSC69112.1 - 0.055 13.6 3.2 0.096 12.8 0.6 2.4 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 PSC69112.1 - 0.19 12.2 0.9 0.43 11.0 0.9 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain PPDK_N PF01326.19 PSC69113.1 - 3.8e-27 95.4 0.0 3.1e-26 92.4 0.0 2.2 2 1 0 2 2 2 1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain CBM_20 PF00686.19 PSC69113.1 - 8.8e-22 76.8 0.0 1.8e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain His_Phos_1 PF00300.22 PSC69114.1 - 2e-43 148.4 0.0 4.4e-43 147.2 0.0 1.6 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Methyltransf_11 PF08241.12 PSC69114.1 - 1.1e-16 61.3 0.0 2.6e-16 60.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC69114.1 - 1e-14 55.0 0.0 3.3e-14 53.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC69114.1 - 1.2e-10 42.0 0.0 2.8e-10 40.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC69114.1 - 9.2e-09 35.0 0.0 1.4e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 PSC69114.1 - 2e-07 30.9 0.0 3.5e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC69114.1 - 5.6e-06 26.3 0.0 1.3e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_29 PF03141.16 PSC69114.1 - 0.058 11.9 0.0 0.09 11.3 0.0 1.2 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_5 PF01795.19 PSC69114.1 - 0.19 11.2 0.0 0.39 10.2 0.0 1.4 1 0 0 1 1 1 0 MraW methylase family Zn_Tnp_IS1 PF03811.13 PSC69114.1 - 2.8 7.7 6.2 25 4.7 0.2 3.4 3 0 0 3 3 3 0 InsA N-terminal domain Sec63 PF02889.16 PSC69116.1 - 2.1e-136 453.1 0.0 3.5e-80 268.9 0.0 2.2 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 PSC69116.1 - 1.6e-49 168.1 0.0 4.6e-27 94.9 0.2 2.8 2 0 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.15 PSC69116.1 - 1.3e-22 80.6 0.0 4.6e-10 39.8 0.0 2.5 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PSC69116.1 - 3.7e-15 56.2 0.0 4.1e-07 30.3 0.0 2.9 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_22 PF13401.6 PSC69116.1 - 1.3e-06 28.8 1.4 0.021 15.1 0.0 4.4 4 1 0 4 4 4 2 AAA domain TBSV_P22 PF03558.13 PSC69116.1 - 0.00049 19.6 0.0 0.00092 18.7 0.0 1.3 1 0 0 1 1 1 1 TBSV core protein P21/P22 AAA_19 PF13245.6 PSC69116.1 - 0.00055 20.3 0.4 0.71 10.2 0.5 2.7 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 PSC69116.1 - 0.0022 17.1 0.0 2 7.4 0.0 2.5 2 0 0 2 2 2 2 Type II/IV secretion system protein PhoH PF02562.16 PSC69116.1 - 0.0025 17.3 0.0 1.4 8.4 0.0 2.8 2 0 0 2 2 2 2 PhoH-like protein AAA_7 PF12775.7 PSC69116.1 - 0.0025 17.3 0.4 2.4 7.7 0.0 3.0 4 0 0 4 4 4 2 P-loop containing dynein motor region TniB PF05621.11 PSC69116.1 - 0.068 12.6 1.5 11 5.3 0.0 3.2 2 1 1 3 3 3 0 Bacterial TniB protein AAA_11 PF13086.6 PSC69116.1 - 0.14 11.9 0.0 23 4.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 PSC69116.1 - 0.18 11.5 0.4 1.3 8.7 0.0 2.7 4 0 0 4 4 4 0 IstB-like ATP binding protein PQQ_2 PF13360.6 PSC69117.1 - 1.3e-15 57.7 5.5 2.2e-12 47.1 2.1 2.8 2 1 0 2 2 2 2 PQQ-like domain Lactamase_B PF00753.27 PSC69117.1 - 2.4e-11 44.0 0.2 8.3e-11 42.3 0.1 2.1 3 1 0 3 3 3 1 Metallo-beta-lactamase superfamily PQQ PF01011.21 PSC69117.1 - 5.4e-10 38.7 9.1 0.022 14.7 0.0 5.6 6 0 0 6 6 6 4 PQQ enzyme repeat Lactamase_B_2 PF12706.7 PSC69117.1 - 1.2e-05 25.0 0.0 2.3e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 PSC69117.1 - 0.14 11.5 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain Sulfotransfer_3 PF13469.6 PSC69117.1 - 0.17 12.2 0.0 0.31 11.4 0.0 1.3 1 0 0 1 1 1 0 Sulfotransferase family TPT PF03151.16 PSC69118.1 - 1e-19 71.0 21.4 1.4e-19 70.6 21.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 PSC69118.1 - 3.8e-08 32.9 20.6 5.8e-08 32.3 20.6 1.2 1 0 0 1 1 1 1 UAA transporter family DUF4077 PF13295.6 PSC69118.1 - 6.2e-05 23.0 7.1 6.2e-05 23.0 7.1 2.2 1 1 2 3 3 3 1 Domain of unknown function (DUF4077) NDUF_B7 PF05676.13 PSC69119.1 - 2.4e-26 91.2 6.1 2.4e-26 91.2 6.1 1.6 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 PSC69119.1 - 0.012 15.6 2.7 0.012 15.6 2.7 1.7 1 1 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like REF PF05755.12 PSC69120.1 - 1.4e-06 28.3 3.0 3e-06 27.2 3.0 1.5 1 0 0 1 1 1 1 Rubber elongation factor protein (REF) BTB PF00651.31 PSC69120.1 - 0.017 15.4 0.0 0.13 12.5 0.0 2.2 1 1 0 1 1 1 0 BTB/POZ domain Aa_trans PF01490.18 PSC69121.1 - 8.4e-38 130.1 21.3 1.1e-37 129.8 21.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF2516 PF10724.9 PSC69121.1 - 0.026 14.8 3.3 0.026 14.8 3.3 3.1 4 1 0 4 4 4 0 Protein of unknown function (DUF2516) CDP-OH_P_transf PF01066.21 PSC69122.1 - 1.3e-12 48.3 1.0 1.6e-12 48.0 0.1 1.7 2 0 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Methyltransf_16 PF10294.9 PSC69124.1 - 4.7e-16 59.0 0.0 1.2e-11 44.7 0.0 2.3 2 1 0 2 2 2 2 Lysine methyltransferase PCMT PF01135.19 PSC69124.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SUIM_assoc PF16619.5 PSC69124.1 - 0.041 14.0 4.4 0.065 13.3 4.4 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 MTS PF05175.14 PSC69124.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 PSC69124.1 - 0.13 12.1 0.4 0.42 10.4 0.4 1.9 1 1 0 1 1 1 0 Methyltransferase domain UL42 PF17638.2 PSC69124.1 - 0.21 11.6 0.9 0.4 10.7 0.9 1.4 1 0 0 1 1 1 0 HCMV UL42 Methyltransf_16 PF10294.9 PSC69125.1 - 4.7e-16 59.0 0.0 1.2e-11 44.7 0.0 2.3 2 1 0 2 2 2 2 Lysine methyltransferase PCMT PF01135.19 PSC69125.1 - 0.011 15.5 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) SUIM_assoc PF16619.5 PSC69125.1 - 0.041 14.0 4.4 0.065 13.3 4.4 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 MTS PF05175.14 PSC69125.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.6 PSC69125.1 - 0.13 12.1 0.4 0.42 10.4 0.4 1.9 1 1 0 1 1 1 0 Methyltransferase domain UL42 PF17638.2 PSC69125.1 - 0.21 11.6 0.9 0.4 10.7 0.9 1.4 1 0 0 1 1 1 0 HCMV UL42 ORC_WH_C PF18137.1 PSC69126.1 - 4.9 7.2 11.3 0.063 13.3 2.4 2.3 3 0 0 3 3 3 0 Origin recognition complex winged helix C-terminal AhpC-TSA_2 PF13911.6 PSC69127.1 - 4e-19 68.8 0.0 1.8e-18 66.7 0.0 2.1 2 1 0 2 2 2 1 AhpC/TSA antioxidant enzyme DSPc PF00782.20 PSC69127.1 - 8.9e-06 25.6 0.0 1.4e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain NAD_binding_10 PF13460.6 PSC69127.1 - 0.071 13.0 2.3 0.16 11.8 2.3 1.6 1 0 0 1 1 1 0 NAD(P)H-binding AhpC-TSA PF00578.21 PSC69127.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 AhpC/TSA family DUF2726 PF10881.8 PSC69127.1 - 0.13 12.1 0.1 0.27 11.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) Cyt-b5 PF00173.28 PSC69128.1 - 1.7e-19 69.7 0.0 1.5e-10 41.1 0.0 2.3 2 0 0 2 2 2 2 Cytochrome b5-like Heme/Steroid binding domain DUF2722 PF10846.8 PSC69129.1 - 0.00019 20.5 7.3 0.00025 20.1 7.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF719 PF05334.13 PSC69129.1 - 0.037 14.2 1.2 0.068 13.4 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF719) Spt20 PF12090.8 PSC69129.1 - 0.094 12.3 21.0 0.16 11.5 21.0 1.3 1 0 0 1 1 1 0 Spt20 family CrgA PF06781.12 PSC69129.1 - 0.19 11.8 0.1 0.41 10.7 0.1 1.5 1 0 0 1 1 1 0 Cell division protein CrgA Presenilin PF01080.17 PSC69129.1 - 0.45 9.2 1.6 0.64 8.7 1.6 1.2 1 0 0 1 1 1 0 Presenilin Peptidase_C58 PF03543.14 PSC69129.1 - 0.5 10.0 9.6 0.15 11.8 5.3 2.0 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen Pex14_N PF04695.13 PSC69129.1 - 0.51 11.0 10.5 0.53 10.9 8.6 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Connexin PF00029.19 PSC69129.1 - 0.53 10.0 1.5 7.6 6.2 0.9 2.2 2 0 0 2 2 2 0 Connexin Suf PF05843.14 PSC69129.1 - 0.9 9.5 9.2 1.6 8.7 9.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4834 PF16118.5 PSC69129.1 - 1.3 10.1 8.3 2.7 9.0 8.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DivIC PF04977.15 PSC69129.1 - 4.2 7.2 12.1 8.6 6.2 12.1 1.5 1 0 0 1 1 1 0 Septum formation initiator TMEM51 PF15345.6 PSC69129.1 - 6.3 6.6 10.4 13 5.5 10.4 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Mpv17_PMP22 PF04117.12 PSC69130.1 - 6.9e-28 96.7 11.5 3.5e-16 59.2 2.3 3.1 3 0 0 3 3 3 2 Mpv17 / PMP22 family Mpv17_PMP22 PF04117.12 PSC69131.1 - 6.9e-28 96.7 11.5 3.5e-16 59.2 2.3 3.1 3 0 0 3 3 3 2 Mpv17 / PMP22 family SBP PF03110.14 PSC69132.1 - 7.2e-22 77.5 1.7 3.4e-21 75.3 1.7 1.9 1 1 0 1 1 1 1 SBP domain zf-NADH-PPase PF09297.11 PSC69132.1 - 0.0021 17.7 0.2 0.0021 17.7 0.2 1.9 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain CxC6 PF18721.1 PSC69132.1 - 7.1 7.0 9.0 30 5.0 8.8 2.3 1 1 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases SBP PF03110.14 PSC69133.1 - 3.1e-24 85.1 2.7 4.8e-24 84.5 2.7 1.2 1 0 0 1 1 1 1 SBP domain zf-NADH-PPase PF09297.11 PSC69133.1 - 0.0019 17.8 0.2 0.0019 17.8 0.2 1.9 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain CxC6 PF18721.1 PSC69133.1 - 0.12 12.6 8.4 0.36 11.1 8.4 1.9 1 1 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases CAP_N PF01213.19 PSC69133.1 - 3.7 7.0 3.9 4.9 6.5 3.9 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SBP PF03110.14 PSC69134.1 - 3.1e-24 85.1 2.7 4.8e-24 84.5 2.7 1.2 1 0 0 1 1 1 1 SBP domain zf-NADH-PPase PF09297.11 PSC69134.1 - 0.0019 17.8 0.2 0.0019 17.8 0.2 1.9 2 0 0 2 2 2 1 NADH pyrophosphatase zinc ribbon domain CxC6 PF18721.1 PSC69134.1 - 0.12 12.6 8.4 0.36 11.1 8.4 1.9 1 1 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases CAP_N PF01213.19 PSC69134.1 - 3.7 7.0 3.9 4.9 6.5 3.9 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal DSPc PF00782.20 PSC69135.1 - 1.6e-08 34.4 0.0 2.7e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PSC69135.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family adh_short PF00106.25 PSC69136.1 - 6.9e-28 97.4 0.0 1.1e-27 96.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Radical_SAM PF04055.21 PSC69136.1 - 1.1e-20 74.7 0.0 2.1e-20 73.8 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily adh_short_C2 PF13561.6 PSC69136.1 - 1.4e-18 67.3 0.0 2.3e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_deac_1 PF01522.21 PSC69136.1 - 2.2e-10 40.5 0.1 7.5e-10 38.8 0.0 1.9 2 0 0 2 2 2 1 Polysaccharide deacetylase KR PF08659.10 PSC69136.1 - 5e-07 29.8 1.0 1.6e-05 24.9 0.1 3.0 3 0 0 3 3 3 1 KR domain DUF1776 PF08643.10 PSC69136.1 - 0.0066 15.9 0.0 0.023 14.1 0.0 1.8 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) HemN_C PF06969.16 PSC69136.1 - 0.018 15.1 0.0 0.051 13.6 0.0 1.8 1 0 0 1 1 1 0 HemN C-terminal domain SBP PF03110.14 PSC69137.1 - 3.1e-21 75.4 12.6 5.5e-21 74.7 12.6 1.4 1 0 0 1 1 1 1 SBP domain DUF2052 PF09747.9 PSC69137.1 - 0.0099 16.0 15.4 0.015 15.4 15.4 1.3 1 0 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) TFIIF_alpha PF05793.12 PSC69137.1 - 0.026 13.1 10.5 0.037 12.6 10.5 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 PSC69137.1 - 0.31 9.2 13.7 0.41 8.8 13.7 1.0 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 PSC69137.1 - 0.49 8.6 16.2 0.65 8.2 16.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Lin-8 PF03353.15 PSC69137.1 - 1.1 8.8 8.7 1.5 8.4 8.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Paf1 PF03985.13 PSC69137.1 - 3.1 6.7 21.0 4.3 6.2 21.0 1.1 1 0 0 1 1 1 0 Paf1 DUF3807 PF12720.7 PSC69137.1 - 5.3 7.3 16.4 7.7 6.7 16.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF913 PF06025.12 PSC69137.1 - 5.5 5.9 4.7 7.3 5.4 4.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) FYDLN_acid PF09538.10 PSC69137.1 - 5.5 7.7 15.2 1.3 9.7 11.1 2.0 1 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Merozoite_SPAM PF07133.11 PSC69137.1 - 5.7 6.9 21.3 7.9 6.4 21.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Hid1 PF12722.7 PSC69137.1 - 8.7 4.3 8.4 11 4.1 8.4 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein WD40 PF00400.32 PSC69138.1 - 2e-20 72.7 9.4 8e-07 29.7 0.0 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC69138.1 - 5.3e-09 36.3 0.0 1 9.7 0.0 5.1 1 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PSC69138.1 - 0.13 11.2 0.0 5.1 6.0 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein RNase_P_Rpp14 PF01900.19 PSC69139.1 - 5.2e-25 87.7 0.0 1.1e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 Rpp14/Pop5 family SAS-6_N PF16531.5 PSC69139.1 - 1.2e-17 64.2 0.0 2.8e-17 63.1 0.0 1.7 1 0 0 1 1 1 1 Centriolar protein SAS N-terminal RRM_1 PF00076.22 PSC69139.1 - 1.4e-07 31.3 0.0 0.13 12.2 0.0 3.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1664 PF07889.12 PSC69139.1 - 0.008 16.2 8.1 0.39 10.8 0.4 3.7 2 1 1 4 4 4 2 Protein of unknown function (DUF1664) RRM_occluded PF16842.5 PSC69139.1 - 0.031 14.1 0.0 4.4 7.2 0.0 2.6 2 0 0 2 2 2 0 Occluded RNA-recognition motif Spc7 PF08317.11 PSC69139.1 - 0.69 8.7 43.1 0.074 11.9 11.0 3.6 1 1 2 3 3 3 0 Spc7 kinetochore protein FlaC_arch PF05377.11 PSC69139.1 - 0.79 10.2 3.8 16 6.0 0.3 3.7 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) FAD_binding_3 PF01494.19 PSC69140.1 - 3e-15 56.3 0.1 8e-15 54.9 0.1 1.6 1 1 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 PSC69140.1 - 1.1e-12 47.5 0.0 1.3e-05 24.2 0.0 3.0 3 0 0 3 3 3 3 Tryptophan halogenase DAO PF01266.24 PSC69140.1 - 7.6e-08 32.3 0.2 9.6e-05 22.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PSC69140.1 - 1.5e-06 28.3 0.1 5.4e-06 26.6 0.1 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 PSC69140.1 - 4.1e-06 26.2 0.8 2.5e-05 23.7 0.2 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PSC69140.1 - 7.5e-06 25.3 0.3 1.1e-05 24.7 0.3 1.3 1 1 0 1 1 1 1 Glucose inhibited division protein A Thi4 PF01946.17 PSC69140.1 - 1.2e-05 24.7 0.3 3.3e-05 23.2 0.3 1.7 1 1 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 PSC69140.1 - 4.3e-05 22.4 0.2 7.9e-05 21.5 0.0 1.4 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.24 PSC69140.1 - 0.00011 21.4 0.0 0.00019 20.6 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 PSC69140.1 - 0.0082 15.5 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase ApbA PF02558.16 PSC69140.1 - 0.012 15.2 0.1 0.027 14.1 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 PSC69140.1 - 0.075 13.6 0.0 0.18 12.4 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 PSC69140.1 - 0.11 11.5 0.9 19 4.2 1.3 2.9 2 1 0 2 2 2 0 Lycopene cyclase protein Pyr_redox_3 PF13738.6 PSC69140.1 - 0.2 10.9 0.1 0.33 10.2 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase PhoD PF09423.10 PSC69141.1 - 2.8e-69 233.8 1.1 5.1e-67 226.4 1.0 2.1 2 0 0 2 2 2 2 PhoD-like phosphatase RNase_PH PF01138.21 PSC69141.1 - 4.7e-32 111.3 0.0 9e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 PhoD_N PF16655.5 PSC69141.1 - 3.2e-24 85.3 0.3 7.5e-24 84.1 0.3 1.7 1 0 0 1 1 1 1 PhoD-like phosphatase, N-terminal domain RNase_PH_C PF03725.15 PSC69141.1 - 1.2e-08 34.8 0.0 2.4e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Pur_ac_phosph_N PF16656.5 PSC69141.1 - 0.0051 17.3 0.1 0.011 16.3 0.1 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Arm PF00514.23 PSC69142.1 - 4.4e-33 112.3 31.0 1.3e-07 31.4 1.4 6.3 6 0 0 6 6 6 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 PSC69142.1 - 1.3e-13 51.2 31.5 0.004 17.6 1.9 6.5 5 1 1 6 6 6 5 HEAT-like repeat HEAT PF02985.22 PSC69142.1 - 2.5e-10 39.7 23.4 0.0069 16.6 0.7 6.7 6 0 0 6 6 6 4 HEAT repeat HEAT_2 PF13646.6 PSC69142.1 - 2.1e-09 37.6 31.5 1.3e-05 25.5 9.8 4.0 2 2 1 3 3 3 3 HEAT repeats zf-MYND PF01753.18 PSC69142.1 - 1.8e-07 31.1 12.1 3.7e-07 30.1 12.1 1.5 1 0 0 1 1 1 1 MYND finger Arm_2 PF04826.13 PSC69142.1 - 0.0012 18.3 0.1 0.55 9.6 0.0 2.9 1 1 2 3 3 3 2 Armadillo-like DUF3361 PF11841.8 PSC69142.1 - 0.0091 15.9 0.0 0.077 12.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) DUF1467 PF07330.12 PSC69142.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1467) V-ATPase_H_C PF11698.8 PSC69142.1 - 0.14 12.3 0.0 5.8 7.1 0.0 2.8 2 1 2 4 4 4 0 V-ATPase subunit H DUF4704 PF15787.5 PSC69142.1 - 0.18 11.0 0.1 0.55 9.4 0.0 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4704) Meleagrin PF08189.11 PSC69142.1 - 0.25 11.0 2.6 0.57 9.9 2.6 1.5 1 0 0 1 1 1 0 Meleagrin/Cygnin family C5-epim_C PF06662.13 PSC69142.1 - 0.53 9.8 1.6 0.78 9.2 0.1 1.8 2 0 0 2 2 2 0 D-glucuronyl C5-epimerase C-terminus IFRD PF05004.13 PSC69142.1 - 1.9 7.5 11.0 0.6 9.2 2.5 2.5 1 1 1 2 2 2 0 Interferon-related developmental regulator (IFRD) Alkyl_sulf_dimr PF14863.6 PSC69142.1 - 5 7.6 8.7 17 5.9 0.1 3.1 1 1 0 3 3 3 0 Alkyl sulfatase dimerisation Methyltransf_4 PF02390.17 PSC69143.1 - 1.4e-31 109.3 0.0 3e-31 108.2 0.0 1.5 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_25 PF13649.6 PSC69143.1 - 9.5e-10 39.1 0.0 1.9e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC69143.1 - 2e-08 34.1 0.0 3.1e-08 33.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC69143.1 - 9.8e-06 25.5 0.0 3.9e-05 23.5 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC69143.1 - 3.6e-05 24.3 0.0 6.8e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC69143.1 - 8.5e-05 23.2 0.1 0.00046 20.9 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PSC69143.1 - 0.00031 20.3 0.0 0.00056 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.6 PSC69143.1 - 0.00037 20.5 0.0 0.00061 19.8 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Peptidase_S8 PF00082.22 PSC69144.1 - 1.5e-10 40.9 0.1 1.8e-10 40.6 0.1 1.3 1 0 0 1 1 1 1 Subtilase family CAP_N PF01213.19 PSC69144.1 - 2.7 7.4 6.6 6.6 6.1 6.6 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 PSC69144.1 - 4.7 7.2 4.4 8 6.5 4.4 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator PRIMA1 PF16101.5 PSC69144.1 - 7.3 6.7 8.8 15 5.7 8.8 1.4 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 PseudoU_synth_2 PF00849.22 PSC69145.1 - 5.3e-25 88.4 0.0 9e-13 48.6 0.0 2.7 2 1 0 2 2 2 2 RNA pseudouridylate synthase HA2 PF04408.23 PSC69146.1 - 7.1e-21 74.5 0.0 7.1e-21 74.5 0.0 3.4 5 0 0 5 5 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PSC69146.1 - 8.7e-15 54.9 0.0 1.7e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PSC69146.1 - 5.7e-12 46.0 0.0 1.3e-11 44.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PSC69146.1 - 1e-06 28.6 0.1 1.9e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PSC69146.1 - 1.6e-05 25.2 0.1 5.1e-05 23.6 0.0 1.8 2 0 0 2 2 1 1 AAA domain AAA_30 PF13604.6 PSC69146.1 - 0.0004 20.1 0.0 0.0011 18.7 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF2075 PF09848.9 PSC69146.1 - 0.0042 16.4 0.0 0.0081 15.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_24 PF13479.6 PSC69146.1 - 0.017 14.9 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PSC69146.1 - 0.021 14.4 0.1 0.039 13.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 PSC69146.1 - 0.022 13.8 0.0 0.044 12.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.6 PSC69146.1 - 0.027 14.8 0.1 0.061 13.7 0.1 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 PSC69146.1 - 0.047 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 PSC69146.1 - 0.052 13.7 5.4 0.15 12.2 0.3 3.7 3 1 0 3 3 3 0 AAA domain ATPase PF06745.13 PSC69146.1 - 0.064 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 KaiC Flavi_DEAD PF07652.14 PSC69146.1 - 0.087 12.8 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain SRP54 PF00448.22 PSC69146.1 - 0.094 12.3 0.0 0.21 11.2 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_14 PF13173.6 PSC69146.1 - 0.12 12.4 0.1 0.81 9.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PSC69146.1 - 0.16 12.5 0.0 0.55 10.7 0.0 1.9 1 0 0 1 1 1 0 ABC transporter cobW PF02492.19 PSC69146.1 - 0.18 11.4 0.6 1.6 8.3 0.1 2.4 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Pkinase_Tyr PF07714.17 PSC69147.1 - 2.2e-46 158.3 0.0 9e-40 136.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PSC69147.1 - 1.9e-38 132.3 0.0 1.4e-28 100.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain RNA_pol_3_Rpc31 PF11705.8 PSC69147.1 - 0.0052 17.1 0.9 0.012 15.9 0.9 1.6 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF2052 PF09747.9 PSC69147.1 - 0.62 10.2 9.1 0.23 11.6 0.8 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Radial_spoke PF04712.12 PSC69147.1 - 1.6 7.6 7.0 2.5 6.9 7.0 1.2 1 0 0 1 1 1 0 Radial spokehead-like protein DNA_pol_phi PF04931.13 PSC69147.1 - 2.2 6.2 7.8 3.3 5.7 7.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi BSP_II PF05432.11 PSC69147.1 - 2.9 7.5 11.3 7.6 6.1 6.0 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) NOA36 PF06524.12 PSC69147.1 - 4.1 6.7 7.9 8.7 5.6 7.9 1.4 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 PSC69147.1 - 7.4 7.0 13.9 16 5.9 13.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain TFIIIC_sub6 PF10419.9 PSC69148.1 - 5.3e-07 29.4 0.0 1e-06 28.5 0.0 1.4 1 1 0 1 1 1 1 TFIIIC subunit triple barrel domain SURF2 PF05477.11 PSC69149.1 - 4.6e-24 85.4 0.8 4.6e-24 85.4 0.8 2.9 1 1 2 3 3 3 1 Surfeit locus protein 2 (SURF2) DNA_pol_phi PF04931.13 PSC69149.1 - 0.16 10.0 7.6 0.28 9.2 7.6 1.3 1 0 0 1 1 1 0 DNA polymerase phi GREB1 PF15782.5 PSC69149.1 - 4.7 4.2 6.4 6 3.8 6.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Bromodomain PF00439.25 PSC69150.1 - 6.2e-16 58.3 0.0 1.2e-15 57.3 0.0 1.4 1 0 0 1 1 1 1 Bromodomain GBP_C PF02841.14 PSC69150.1 - 0.049 13.0 0.0 0.049 13.0 0.0 3.5 3 1 1 4 4 4 0 Guanylate-binding protein, C-terminal domain Spc7 PF08317.11 PSC69150.1 - 3.3 6.5 32.7 6.2 5.6 32.7 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein ERM PF00769.19 PSC69150.1 - 4.1 7.1 52.3 0.034 14.0 41.9 2.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family RNB PF00773.19 PSC69151.1 - 5.1e-80 269.2 0.0 6.8e-80 268.8 0.0 1.1 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 PSC69151.1 - 2.3e-15 56.3 0.0 4.1e-15 55.6 0.0 1.4 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 PSC69151.1 - 0.00034 20.3 0.0 0.00087 19.0 0.0 1.6 2 0 0 2 2 2 1 Rrp44-like cold shock domain cobW PF02492.19 PSC69152.1 - 2.2e-56 190.2 2.6 2.9e-56 189.9 2.6 1.1 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 PSC69152.1 - 2.4e-21 75.4 0.0 4.9e-21 74.5 0.0 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 PSC69152.1 - 6.6e-05 22.9 0.2 0.29 11.0 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 PSC69152.1 - 0.00058 20.3 0.4 0.0029 18.0 0.4 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PSC69152.1 - 0.001 19.4 0.1 0.003 17.8 0.0 1.8 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 PSC69152.1 - 0.0012 18.5 0.1 1.4 8.4 0.0 2.2 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain T2SSE PF00437.20 PSC69152.1 - 0.016 14.3 0.2 0.035 13.2 0.2 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein MobB PF03205.14 PSC69152.1 - 0.017 15.1 0.1 0.099 12.5 0.1 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.10 PSC69152.1 - 0.021 14.3 0.3 0.087 12.3 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit MeaB PF03308.16 PSC69152.1 - 0.023 13.7 0.8 0.19 10.7 0.1 2.5 2 1 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_33 PF13671.6 PSC69152.1 - 0.024 14.8 0.0 0.062 13.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 PSC69152.1 - 0.024 14.6 0.7 0.047 13.6 0.0 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_29 PF13555.6 PSC69152.1 - 0.029 14.1 0.1 0.21 11.4 0.1 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 PSC69152.1 - 0.034 14.2 2.0 0.44 10.6 2.0 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Viral_helicase1 PF01443.18 PSC69152.1 - 0.054 13.2 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_14 PF13173.6 PSC69152.1 - 0.065 13.3 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 PSC69152.1 - 0.082 12.8 0.3 0.2 11.5 0.3 1.7 1 0 0 1 1 1 0 NTPase AAA_23 PF13476.6 PSC69152.1 - 0.082 13.4 0.9 0.34 11.4 0.2 2.0 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PSC69152.1 - 0.094 13.0 0.5 0.66 10.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Arf PF00025.21 PSC69152.1 - 0.12 11.8 2.0 6.2 6.2 0.8 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family AAA_18 PF13238.6 PSC69152.1 - 0.13 12.8 0.4 0.5 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain Lactonase PF10282.9 PSC69153.1 - 6.7e-49 167.0 0.0 2.6e-48 165.0 0.0 1.7 1 1 0 1 1 1 1 Lactonase, 7-bladed beta-propeller Cyt-b5 PF00173.28 PSC69154.1 - 2.1e-16 59.8 0.1 5e-16 58.6 0.1 1.6 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Pre-PUA PF17832.1 PSC69155.1 - 1.8e-17 63.8 0.0 1.7e-16 60.6 0.0 2.5 3 0 0 3 3 3 1 Pre-PUA-like domain SUI1 PF01253.22 PSC69155.1 - 3.3e-15 56.4 0.0 7.8e-15 55.2 0.0 1.7 1 0 0 1 1 1 1 Translation initiation factor SUI1 ALIX_LYPXL_bnd PF13949.6 PSC69155.1 - 0.052 12.8 0.1 0.052 12.8 0.1 1.4 2 0 0 2 2 2 0 ALIX V-shaped domain binding to HIV RRP7 PF12923.7 PSC69155.1 - 0.37 10.9 1.4 0.89 9.7 1.4 1.5 1 0 0 1 1 1 0 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain DUF2358 PF10184.9 PSC69156.1 - 2.8e-05 24.4 0.0 4.6e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) eIF-3_zeta PF05091.12 PSC69157.1 - 8.8e-05 21.7 7.4 0.00011 21.3 7.4 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3402 PF11882.8 PSC69157.1 - 0.0012 18.0 4.9 0.0013 17.9 4.9 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3402) TFIIA PF03153.13 PSC69157.1 - 0.0039 17.2 20.2 0.0041 17.2 20.2 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 PSC69157.1 - 0.0098 14.7 3.5 0.0092 14.8 3.5 1.1 1 0 0 1 1 1 1 Presenilin Suf PF05843.14 PSC69157.1 - 0.011 15.7 9.2 0.017 15.2 9.2 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF913 PF06025.12 PSC69157.1 - 0.015 14.3 2.7 0.019 13.9 2.7 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) SpoIIP PF07454.11 PSC69157.1 - 0.018 14.5 5.0 0.022 14.2 5.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DDHD PF02862.17 PSC69157.1 - 0.019 15.2 2.7 0.02 15.1 2.7 1.1 1 0 0 1 1 1 0 DDHD domain ABC2_membrane_2 PF12679.7 PSC69157.1 - 0.033 13.5 1.6 0.041 13.2 1.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein RR_TM4-6 PF06459.12 PSC69157.1 - 0.037 13.9 3.4 0.043 13.6 3.4 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Lipin_mid PF16876.5 PSC69157.1 - 0.039 14.1 5.3 0.069 13.3 5.3 1.6 1 1 0 1 1 1 0 Lipin/Ned1/Smp2 multi-domain protein middle domain MCD PF05292.11 PSC69157.1 - 0.064 12.8 3.1 0.092 12.3 3.1 1.2 1 0 0 1 1 1 0 Malonyl-CoA decarboxylase C-terminal domain DUF1980 PF09323.10 PSC69157.1 - 0.091 12.7 1.2 0.11 12.4 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) CPSF100_C PF13299.6 PSC69157.1 - 0.098 12.8 5.9 0.14 12.4 5.9 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TrbI PF03743.14 PSC69157.1 - 0.12 12.2 9.1 0.18 11.7 9.1 1.1 1 0 0 1 1 1 0 Bacterial conjugation TrbI-like protein Peroxin-13_N PF04088.13 PSC69157.1 - 0.19 12.0 1.1 0.29 11.4 1.1 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Spt20 PF12090.8 PSC69157.1 - 0.2 11.3 27.1 0.31 10.6 27.1 1.3 1 0 0 1 1 1 0 Spt20 family Connexin PF00029.19 PSC69157.1 - 0.26 11.0 4.1 0.37 10.5 4.1 1.2 1 0 0 1 1 1 0 Connexin PAT1 PF09770.9 PSC69157.1 - 0.4 8.9 17.6 0.41 8.9 17.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ALMT PF11744.8 PSC69157.1 - 0.42 9.4 2.4 0.5 9.1 2.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Serinc PF03348.15 PSC69157.1 - 0.61 9.0 1.1 0.69 8.8 1.1 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) dsRBD2 PF17842.1 PSC69157.1 - 0.66 10.2 6.2 2.7 8.2 4.5 2.1 2 0 0 2 2 2 0 Double-stranded RNA binding domain 2 TERB2 PF15101.6 PSC69157.1 - 0.69 9.9 12.1 0.99 9.4 12.1 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 EIIBC-GUT_N PF03612.14 PSC69157.1 - 1.1 8.9 5.1 1.5 8.5 5.1 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus PepSY_TM PF03929.16 PSC69157.1 - 1.2 8.8 4.9 1.8 8.2 4.9 1.3 1 0 0 1 1 1 0 PepSY-associated TM region V_ATPase_I PF01496.19 PSC69157.1 - 1.2 6.9 7.7 1.6 6.6 7.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CLN3 PF02487.17 PSC69157.1 - 1.6 7.7 4.7 2 7.4 4.7 1.1 1 0 0 1 1 1 0 CLN3 protein VIT1 PF01988.19 PSC69157.1 - 1.8 8.4 4.6 3 7.7 4.6 1.3 1 0 0 1 1 1 0 VIT family SprA-related PF12118.8 PSC69157.1 - 2.4 7.2 21.7 3.3 6.8 21.7 1.1 1 0 0 1 1 1 0 SprA-related family DUF4834 PF16118.5 PSC69157.1 - 3.3 8.7 12.7 1.1 10.2 10.1 1.6 2 0 0 2 2 1 0 Domain of unknown function (DUF4834) UPF0560 PF10577.9 PSC69157.1 - 3.5 6.0 15.2 5 5.5 15.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3464 PF11947.8 PSC69157.1 - 6.6 6.5 9.5 9.9 5.9 9.5 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CTD_bind PF04818.13 PSC69158.1 - 2.3e-08 34.8 0.0 4.1e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II-binding domain. UPF0061 PF02696.14 PSC69159.1 - 2.6e-127 425.5 0.0 3.6e-127 425.0 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized ACR, YdiU/UPF0061 family FAD_binding_4 PF01565.23 PSC69159.1 - 1.7e-29 102.3 3.1 5.5e-29 100.7 2.8 2.1 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 PSC69159.1 - 0.0092 16.1 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 1 Berberine and berberine like RRM_1 PF00076.22 PSC69160.1 - 1.2e-18 66.7 0.0 1.3e-09 37.7 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RAI1 PF08652.11 PSC69161.1 - 0.093 12.9 1.2 0.31 11.2 1.2 1.9 1 0 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease Serglycin PF04360.12 PSC69161.1 - 3.8 7.4 7.2 8.3 6.4 7.2 1.5 1 0 0 1 1 1 0 Serglycin zf-MYND PF01753.18 PSC69162.1 - 5.5e-08 32.8 13.8 5.5e-08 32.8 13.8 2.7 3 0 0 3 3 3 1 MYND finger LRR_8 PF13855.6 PSC69162.1 - 0.0099 15.6 0.0 0.031 14.0 0.0 1.8 1 0 0 1 1 1 1 Leucine rich repeat DUF937 PF06078.11 PSC69162.1 - 0.46 11.1 11.3 1.8 9.2 9.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) zf-MYND PF01753.18 PSC69163.1 - 5.5e-08 32.8 13.8 5.5e-08 32.8 13.8 2.7 3 0 0 3 3 3 1 MYND finger LRR_8 PF13855.6 PSC69163.1 - 0.0099 15.6 0.0 0.031 14.0 0.0 1.8 1 0 0 1 1 1 1 Leucine rich repeat DUF937 PF06078.11 PSC69163.1 - 0.45 11.1 11.3 1.8 9.2 9.2 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF937) LRR_8 PF13855.6 PSC69164.1 - 2.1e-06 27.4 9.2 0.13 12.0 0.0 6.5 7 1 0 7 7 7 3 Leucine rich repeat LRR_4 PF12799.7 PSC69164.1 - 1.9e-05 24.9 8.4 0.087 13.3 0.3 6.2 6 1 2 8 8 8 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC69165.1 - 1.6e-07 30.9 7.4 0.13 12.0 0.0 6.4 7 1 0 7 7 7 4 Leucine rich repeat LRR_4 PF12799.7 PSC69165.1 - 1.2e-05 25.5 7.9 0.086 13.3 0.3 6.2 6 1 3 9 9 9 4 Leucine Rich repeats (2 copies) eIF-3_zeta PF05091.12 PSC69167.1 - 4.8e-136 454.8 0.0 9.3e-136 453.8 0.0 1.4 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) UCH PF00443.29 PSC69168.1 - 3.7e-07 29.9 0.0 8.2e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DOCK_N PF16172.5 PSC69168.1 - 1 8.2 5.8 2.7 6.8 5.8 1.6 1 0 0 1 1 1 0 DOCK N-terminus UCH PF00443.29 PSC69169.1 - 3.7e-07 29.9 0.0 8.1e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DOCK_N PF16172.5 PSC69169.1 - 0.99 8.3 5.8 2.7 6.8 5.8 1.7 1 0 0 1 1 1 0 DOCK N-terminus WD40 PF00400.32 PSC69170.1 - 1.6e-05 25.6 0.5 0.47 11.4 0.0 4.5 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC69170.1 - 0.0002 21.6 0.0 0.088 13.1 0.0 4.0 3 2 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain YABBY PF04690.13 PSC69170.1 - 0.15 12.6 0.1 0.15 12.6 0.1 3.2 3 0 0 3 3 3 0 YABBY protein CemA PF03040.14 PSC69171.1 - 2.4e-66 224.0 0.1 3e-66 223.7 0.1 1.1 1 0 0 1 1 1 1 CemA family TFIIA PF03153.13 PSC69171.1 - 0.00059 20.0 3.5 0.00093 19.3 3.5 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit NleF_casp_inhib PF16809.5 PSC69171.1 - 0.15 11.9 0.1 0.24 11.3 0.1 1.3 1 0 0 1 1 1 0 NleF caspase inhibitor Ribosomal_L32p PF01783.23 PSC69172.1 - 7.3e-06 26.2 2.6 1.1e-05 25.6 2.6 1.2 1 0 0 1 1 1 1 Ribosomal L32p protein family Carla_C4 PF01623.17 PSC69172.1 - 0.027 14.4 0.7 0.037 14.0 0.7 1.2 1 0 0 1 1 1 0 Carlavirus putative nucleic acid binding protein Evr1_Alr PF04777.13 PSC69172.1 - 0.034 14.6 0.3 0.046 14.2 0.3 1.2 1 0 0 1 1 1 0 Erv1 / Alr family MCM_OB PF17207.3 PSC69172.1 - 0.084 12.7 1.2 0.11 12.3 1.2 1.2 1 0 0 1 1 1 0 MCM OB domain Aminotran_4 PF01063.19 PSC69173.1 - 3.3e-19 69.7 0.0 4.3e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV PP2C PF00481.21 PSC69174.1 - 2.5e-18 66.6 0.0 7.4e-18 65.1 0.0 1.7 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 PSC69174.1 - 0.00088 19.0 1.6 0.0022 17.6 1.6 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SAP PF02037.27 PSC69175.1 - 2.7e-12 46.2 2.0 2.7e-11 42.9 2.2 2.5 2 0 0 2 2 2 1 SAP domain Tho1_MOS11_C PF18592.1 PSC69175.1 - 7.2e-05 22.5 18.1 0.003 17.3 1.8 4.4 3 1 1 4 4 4 3 Tho1/MOS11 C-terminal domain HeH PF12949.7 PSC69175.1 - 0.023 14.4 0.1 0.048 13.4 0.1 1.6 1 0 0 1 1 1 0 HeH/LEM domain MOFRL PF05161.13 PSC69175.1 - 0.19 11.9 0.2 0.19 11.9 0.2 2.7 2 1 1 3 3 3 0 MOFRL family Pkinase PF00069.25 PSC69176.1 - 1.5e-62 211.4 0.0 2e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC69176.1 - 2.9e-26 92.3 0.0 4.3e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PSC69176.1 - 0.0091 15.9 1.1 0.024 14.5 0.0 2.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Herpes_BLRF2 PF05812.12 PSC69176.1 - 0.059 13.5 0.5 0.13 12.4 0.5 1.6 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein UCH PF00443.29 PSC69177.1 - 1.5e-19 70.5 0.0 2.9e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PSC69177.1 - 0.001 18.8 0.0 0.015 14.9 0.0 2.7 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Ntox34 PF15606.6 PSC69177.1 - 0.13 12.4 1.1 25 5.1 0.1 3.0 2 0 0 2 2 2 0 Bacterial toxin 34 DUF3446 PF11928.8 PSC69177.1 - 9.6 6.6 11.2 6.6 7.1 6.8 3.1 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF3433 PF11915.8 PSC69178.1 - 0.098 13.1 2.0 0.11 12.9 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3433) DUF1997 PF09366.10 PSC69180.1 - 5.5e-40 137.0 0.0 7.9e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1997) U-box PF04564.15 PSC69180.1 - 9.1e-10 38.6 0.1 4.2e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 U-box domain zf-Nse PF11789.8 PSC69180.1 - 5.3e-05 23.0 0.0 0.0023 17.7 0.0 2.4 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-NOSIP PF15906.5 PSC69180.1 - 0.0013 18.8 0.0 0.0035 17.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein UCH PF00443.29 PSC69181.1 - 3.6e-18 66.0 0.0 8.6e-18 64.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PSC69181.1 - 3.1e-05 23.7 0.8 0.00065 19.4 0.8 3.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RR_TM4-6 PF06459.12 PSC69181.1 - 6.7 6.5 13.5 3.1 7.5 6.0 2.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TMEM65 PF10507.9 PSC69182.1 - 2.4e-33 114.3 3.2 2.4e-33 114.3 3.2 2.5 3 0 0 3 3 3 1 Transmembrane protein 65 KicB PF03882.14 PSC69182.1 - 0.056 13.6 0.6 0.1 12.8 0.1 1.6 2 0 0 2 2 2 0 MukF winged-helix domain Romo1 PF10247.9 PSC69182.1 - 0.47 10.8 7.6 0.42 11.0 0.3 3.0 2 1 0 2 2 2 0 Reactive mitochondrial oxygen species modulator 1 UCH PF00443.29 PSC69183.1 - 2.3e-19 69.9 0.4 5.2e-18 65.5 0.0 2.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PSC69183.1 - 0.0015 18.2 0.2 0.0015 18.2 0.2 3.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-CCCH_4 PF18044.1 PSC69183.1 - 0.17 11.7 2.7 0.42 10.5 2.7 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger Ndc1_Nup PF09531.10 PSC69185.1 - 0.12 11.0 4.2 0.26 9.9 4.2 1.6 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Trypsin PF00089.26 PSC69186.1 - 4.9e-15 56.0 1.1 6.6e-15 55.5 1.1 1.2 1 0 0 1 1 1 1 Trypsin Reprolysin_3 PF13582.6 PSC69187.1 - 0.0095 16.5 0.1 0.021 15.3 0.1 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Adap_comp_sub PF00928.21 PSC69188.1 - 4.4e-31 108.2 0.0 6e-31 107.8 0.0 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family ADH_zinc_N PF00107.26 PSC69189.1 - 1.5e-22 79.9 0.3 2.6e-22 79.2 0.3 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PSC69189.1 - 3e-14 54.2 0.0 8e-14 52.8 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PSC69189.1 - 4.9e-11 42.5 0.0 4.7e-10 39.3 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 PSC69189.1 - 0.016 14.7 0.4 0.024 14.1 0.4 1.2 1 0 0 1 1 1 0 short chain dehydrogenase 2-Hacid_dh_C PF02826.19 PSC69189.1 - 0.019 14.4 0.4 0.16 11.3 0.2 2.1 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain T3SS_ATPase_C PF18269.1 PSC69189.1 - 0.032 14.1 0.2 0.078 12.8 0.0 1.7 2 0 0 2 2 2 0 T3SS EscN ATPase C-terminal domain NAD_binding_10 PF13460.6 PSC69189.1 - 0.063 13.2 0.4 0.12 12.3 0.4 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Epimerase PF01370.21 PSC69189.1 - 0.15 11.5 0.1 0.25 10.8 0.1 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family OsmC PF02566.19 PSC69190.1 - 1.4e-16 60.8 0.0 2.1e-16 60.2 0.0 1.2 1 0 0 1 1 1 1 OsmC-like protein CDC45 PF02724.14 PSC69191.1 - 0.033 12.5 1.9 0.037 12.3 1.9 1.2 1 0 0 1 1 1 0 CDC45-like protein CDC45 PF02724.14 PSC69192.1 - 0.033 12.5 1.9 0.037 12.3 1.9 1.2 1 0 0 1 1 1 0 CDC45-like protein PDCD2_C PF04194.13 PSC69193.1 - 1.3e-43 149.1 0.0 3.8e-43 147.6 0.0 1.7 2 0 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain UPF0114 PF03350.16 PSC69194.1 - 0.2 11.8 0.4 1.2 9.4 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 Paf1 PF03985.13 PSC69195.1 - 2.7e-53 181.5 0.0 9.5e-53 179.7 0.0 1.7 1 1 0 1 1 1 1 Paf1 PAN_4 PF14295.6 PSC69196.1 - 0.063 13.2 15.8 0.055 13.4 12.0 2.7 2 1 0 2 2 2 0 PAN domain Mcl1_mid PF12341.8 PSC69197.1 - 1e-79 268.0 0.0 1.5e-79 267.4 0.0 1.3 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 PSC69197.1 - 6.2e-12 45.7 0.3 0.0027 18.0 0.0 5.0 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PSC69197.1 - 1.3e-08 35.3 3.0 0.27 12.2 0.1 6.5 6 1 0 6 6 6 2 WD domain, G-beta repeat Hira PF07569.11 PSC69197.1 - 0.17 11.6 0.2 38 3.9 0.0 3.2 2 1 1 3 3 3 0 TUP1-like enhancer of split Mcl1_mid PF12341.8 PSC69198.1 - 1e-79 268.0 0.0 1.5e-79 267.4 0.0 1.3 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 PSC69198.1 - 6.2e-12 45.7 0.3 0.0027 18.0 0.0 5.0 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PSC69198.1 - 1.3e-08 35.3 3.0 0.27 12.2 0.1 6.5 6 1 0 6 6 6 2 WD domain, G-beta repeat Hira PF07569.11 PSC69198.1 - 0.17 11.6 0.2 39 3.9 0.0 3.2 2 1 1 3 3 3 0 TUP1-like enhancer of split Rab5ip PF07019.12 PSC69199.1 - 2.8e-15 56.7 5.4 5.8e-15 55.6 5.4 1.5 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) GATase PF00117.28 PSC69199.1 - 1.3e-10 41.3 0.0 2.4e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 PSC69199.1 - 0.00023 21.0 0.3 0.00051 19.9 0.3 1.5 1 0 0 1 1 1 1 Peptidase C26 Proton_antipo_M PF00361.20 PSC69199.1 - 0.041 13.1 0.8 0.058 12.6 0.8 1.1 1 0 0 1 1 1 0 Proton-conducting membrane transporter GATase_3 PF07685.14 PSC69199.1 - 0.17 11.4 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Rab5ip PF07019.12 PSC69200.1 - 2.8e-15 56.7 5.4 5.8e-15 55.6 5.4 1.5 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) GATase PF00117.28 PSC69200.1 - 1.3e-10 41.3 0.0 2.4e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 PSC69200.1 - 0.00023 21.0 0.3 0.00051 19.9 0.3 1.5 1 0 0 1 1 1 1 Peptidase C26 Proton_antipo_M PF00361.20 PSC69200.1 - 0.041 13.1 0.8 0.058 12.6 0.8 1.1 1 0 0 1 1 1 0 Proton-conducting membrane transporter GATase_3 PF07685.14 PSC69200.1 - 0.17 11.4 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain CDC27 PF09507.10 PSC69201.1 - 2.4e-30 106.3 44.5 7.2e-28 98.1 44.5 2.4 1 1 0 1 1 1 1 DNA polymerase subunit Cdc27 Rib_5-P_isom_A PF06026.14 PSC69202.1 - 2e-22 79.6 0.0 2.6e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Rib_5-P_isom_A PF06026.14 PSC69203.1 - 1.2e-24 86.9 0.0 1.5e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Zip PF02535.22 PSC69204.1 - 8.5e-48 163.3 9.3 8.5e-48 163.3 9.3 1.7 2 0 0 2 2 2 1 ZIP Zinc transporter TRAPPC9-Trs120 PF08626.11 PSC69204.1 - 4.7e-35 120.4 0.0 1.8e-19 68.8 0.0 3.3 2 1 1 3 3 3 3 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit LSM PF01423.22 PSC69204.1 - 0.00029 20.5 0.0 0.0005 19.7 0.0 1.4 1 0 0 1 1 1 1 LSM domain DUF11 PF01345.18 PSC69204.1 - 0.18 12.1 0.5 5.7 7.3 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function DUF11 Lipase_3 PF01764.25 PSC69206.1 - 1.5e-31 109.2 0.0 3.6e-31 107.9 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) LMF1 PF06762.14 PSC69206.1 - 0.026 13.7 6.2 0.013 14.6 1.0 2.1 2 0 0 2 2 2 0 Lipase maturation factor DUF2974 PF11187.8 PSC69206.1 - 0.08 12.5 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) CHCH PF06747.13 PSC69207.1 - 4.5e-07 29.8 4.3 6.9e-07 29.2 4.3 1.3 1 0 0 1 1 1 1 CHCH domain DUF2076 PF09849.9 PSC69207.1 - 0.017 15.2 8.5 0.02 15.0 8.5 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Colipase-like PF15083.6 PSC69207.1 - 0.039 14.1 0.1 0.049 13.8 0.1 1.1 1 0 0 1 1 1 0 Colipase-like MTCP1 PF08991.10 PSC69207.1 - 0.04 14.1 0.3 0.061 13.6 0.3 1.2 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type CX9C PF16860.5 PSC69207.1 - 0.21 11.6 1.9 0.32 11.0 1.9 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, SDA1 PF05285.12 PSC69208.1 - 0.002 17.6 11.6 0.0028 17.1 11.6 1.1 1 0 0 1 1 1 1 SDA1 CDC45 PF02724.14 PSC69208.1 - 0.008 14.5 10.2 0.0096 14.3 10.2 1.1 1 0 0 1 1 1 1 CDC45-like protein GREB1 PF15782.5 PSC69208.1 - 0.19 8.8 0.1 0.25 8.4 0.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SRP-alpha_N PF04086.13 PSC69208.1 - 1.5 8.7 13.0 0.13 12.1 8.5 1.4 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal COPI_C PF06957.11 PSC69208.1 - 2.2 7.0 6.4 2.7 6.7 6.4 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Roughex PF06020.11 PSC69208.1 - 4.9 6.1 14.0 7.9 5.5 14.0 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Nop14 PF04147.12 PSC69208.1 - 6.9 4.7 16.8 9.3 4.3 16.8 1.1 1 0 0 1 1 1 0 Nop14-like family APC1_C PF18122.1 PSC69209.1 - 0.061 13.3 0.3 0.92 9.4 0.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain DUF1244 PF06844.11 PSC69209.1 - 0.28 11.3 1.0 0.55 10.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) APC1_C PF18122.1 PSC69210.1 - 0.079 12.9 0.3 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex sub unit 1 C-terminal domain DUF1244 PF06844.11 PSC69210.1 - 0.11 12.7 0.2 0.65 10.2 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1244) APC1_C PF18122.1 PSC69211.1 - 0.22 11.5 2.7 0.91 9.4 0.0 2.5 2 1 1 3 3 3 0 Anaphase-promoting complex sub unit 1 C-terminal domain DUF1244 PF06844.11 PSC69211.1 - 0.27 11.4 1.7 0.55 10.4 0.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1244) ASFV_J13L PF05568.11 PSC69211.1 - 4.3 7.0 6.0 9.9 5.9 6.0 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein FAD_binding_4 PF01565.23 PSC69212.1 - 2.2e-26 92.3 5.9 4.3e-26 91.3 5.9 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 PSC69212.1 - 3.2e-05 23.9 0.0 5.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like Peptidase_M41 PF01434.18 PSC69213.1 - 2.8e-65 219.7 0.0 4.5e-65 219.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 PSC69213.1 - 2.2e-44 151.1 0.0 3.9e-44 150.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) WD40 PF00400.32 PSC69213.1 - 2.8e-25 88.1 14.7 3.6e-05 24.5 0.1 8.0 8 0 0 8 8 7 5 WD domain, G-beta repeat NLE PF08154.12 PSC69213.1 - 9.1e-21 74.2 0.0 1.9e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain AAA_lid_3 PF17862.1 PSC69213.1 - 1.7e-16 59.7 0.2 1.2e-15 57.0 0.3 2.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 PSC69213.1 - 0.00037 20.5 0.1 0.0019 18.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 PSC69213.1 - 0.0037 16.5 0.1 0.0074 15.5 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain FtsH_ext PF06480.15 PSC69213.1 - 0.0048 17.2 0.0 0.031 14.6 0.0 2.1 2 0 0 2 2 2 1 FtsH Extracellular AAA_16 PF13191.6 PSC69213.1 - 0.0052 17.2 0.4 0.06 13.7 0.4 2.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_2 PF07724.14 PSC69213.1 - 0.0056 16.8 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 PSC69213.1 - 0.0082 15.9 0.0 0.023 14.4 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PSC69213.1 - 0.011 16.0 0.1 0.11 12.8 0.1 2.3 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 PSC69213.1 - 0.025 14.3 0.0 0.068 12.9 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 PSC69213.1 - 0.072 12.5 0.4 0.14 11.5 0.4 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 PSC69213.1 - 0.086 13.0 0.1 0.2 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PSC69213.1 - 0.09 13.0 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 PSC69213.1 - 0.23 11.5 0.0 0.77 9.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain Aldedh PF00171.22 PSC69214.1 - 7.3e-145 483.0 0.9 9.6e-145 482.6 0.9 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Glutaredoxin PF00462.24 PSC69214.1 - 1.9e-16 60.0 0.0 4.3e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin LuxC PF05893.14 PSC69214.1 - 1.9e-06 27.2 0.3 5.2e-06 25.8 0.3 1.6 1 1 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF1487 PF07368.11 PSC69214.1 - 0.0043 16.5 0.1 0.0085 15.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1487) GST_N_2 PF13409.6 PSC69214.1 - 0.17 12.2 0.0 0.42 11.0 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain ATP-synt_Eps PF04627.13 PSC69216.1 - 4.3e-17 61.8 0.2 5.1e-17 61.6 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Rep_fac_C PF08542.11 PSC69216.1 - 0.094 13.1 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Replication factor C C-terminal domain PP2C PF00481.21 PSC69217.1 - 3.3e-42 144.9 0.0 2.9e-41 141.8 0.0 2.0 1 1 1 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.12 PSC69217.1 - 5.3e-05 23.2 0.6 0.0013 18.7 0.0 2.8 4 0 0 4 4 4 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 PSC69217.1 - 0.025 14.2 9.0 0.43 10.2 9.0 3.1 1 1 0 1 1 1 0 Protein phosphatase 2C Glyco_transf_5 PF08323.11 PSC69218.1 - 8e-62 209.1 0.1 1.3e-61 208.4 0.1 1.4 1 0 0 1 1 1 1 Starch synthase catalytic domain SBF PF01758.16 PSC69218.1 - 1.2e-22 80.6 9.5 1.9e-22 79.9 9.5 1.2 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 PSC69218.1 - 1.2e-15 57.6 14.1 1.8e-15 57.1 14.1 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Glycos_transf_1 PF00534.20 PSC69218.1 - 8.5e-14 51.4 0.0 1.5e-13 50.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PSC69218.1 - 1.2e-12 48.5 0.0 3.2e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 PSC69218.1 - 0.0015 18.5 0.4 0.025 14.6 0.1 2.7 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Mem_trans PF03547.18 PSC69218.1 - 0.63 8.4 4.3 1.1 7.6 4.3 1.4 1 0 0 1 1 1 0 Membrane transport protein Methyltransf_21 PF05050.12 PSC69219.1 - 2.8e-05 24.2 0.0 7.7e-05 22.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_22 PF13383.6 PSC69219.1 - 0.0073 15.9 0.0 0.01 15.4 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Thioredoxin PF00085.20 PSC69220.1 - 8.4e-10 38.6 0.0 8.4e-10 38.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PSC69220.1 - 7e-06 26.5 0.0 7e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 PSC69220.1 - 0.00093 18.6 0.0 0.00099 18.5 0.0 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family HyaE PF07449.11 PSC69220.1 - 0.0037 17.2 0.0 0.004 17.1 0.0 1.1 1 0 0 1 1 1 1 Hydrogenase-1 expression protein HyaE Thioredoxin_8 PF13905.6 PSC69220.1 - 0.11 12.9 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_6 PF13848.6 PSC69220.1 - 0.16 11.9 0.0 0.18 11.7 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain BAR PF03114.18 PSC69221.1 - 3.3e-06 26.9 5.5 4.1e-06 26.6 3.1 2.1 2 0 0 2 2 2 1 BAR domain Biotin_lipoyl PF00364.22 PSC69222.1 - 1.2e-18 66.6 1.9 2.2e-18 65.8 1.9 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Ion_trans PF00520.31 PSC69222.1 - 3.5e-08 33.0 0.1 1.1e-07 31.4 0.1 1.6 1 1 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 PSC69222.1 - 1.7e-06 27.9 0.2 1.7e-06 27.9 0.2 1.9 2 0 0 2 2 2 1 Ion channel cNMP_binding PF00027.29 PSC69222.1 - 2.6e-05 24.2 0.0 9.3e-05 22.4 0.0 2.0 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain HlyD_3 PF13437.6 PSC69222.1 - 7.4e-05 23.4 3.8 0.017 15.8 0.8 2.7 1 1 1 2 2 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 PSC69222.1 - 0.0084 15.9 1.0 3.9 7.4 0.4 2.7 1 1 1 2 2 2 2 Biotin-lipoyl like Ank_2 PF12796.7 PSC69223.1 - 4.6e-18 65.6 8.0 7.4e-10 39.3 0.9 3.5 2 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC69223.1 - 1.1e-15 57.5 8.8 3.1e-08 33.7 0.5 3.6 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC69223.1 - 1.1e-13 51.4 5.0 0.00021 21.8 0.2 4.3 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC69223.1 - 1.1e-13 49.9 7.7 0.024 15.2 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 PSC69223.1 - 1.2e-10 41.3 16.7 0.0018 18.7 0.7 5.6 5 0 0 5 5 5 3 Ankyrin repeat PAN_4 PF14295.6 PSC69223.1 - 1e-05 25.3 5.3 1e-05 25.3 5.3 2.4 2 0 0 2 2 2 1 PAN domain tRNA_edit PF04073.15 PSC69223.1 - 1.8e-05 24.8 0.0 7.1e-05 22.9 0.0 2.0 2 1 0 2 2 2 1 Aminoacyl-tRNA editing domain Matrilin_ccoil PF10393.9 PSC69223.1 - 0.13 12.1 0.2 0.55 10.1 0.1 2.2 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin DNA_binding_1 PF01035.20 PSC69224.1 - 0.04 14.0 0.1 0.061 13.4 0.0 1.4 1 1 0 1 1 1 0 6-O-methylguanine DNA methyltransferase, DNA binding domain Hist_deacetyl PF00850.19 PSC69225.1 - 5.6e-69 232.9 0.0 7e-69 232.6 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain DUF3730 PF12530.8 PSC69226.1 - 1.1e-27 97.2 3.1 1.3e-27 96.9 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF3730) Bac_globin PF01152.21 PSC69226.1 - 0.0037 17.4 0.0 0.13 12.4 0.0 2.6 1 1 1 2 2 2 1 Bacterial-like globin Ribosomal_L11_N PF03946.14 PSC69227.1 - 1.8e-29 101.4 0.2 3.6e-29 100.4 0.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain DUF1499 PF07386.11 PSC69227.1 - 2.7e-29 102.1 0.0 6.5e-29 100.9 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1499) Ribosomal_L11 PF00298.19 PSC69227.1 - 2.3e-28 98.5 0.3 4.8e-28 97.5 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain PsbQ PF05757.11 PSC69227.1 - 0.058 13.1 0.7 0.12 12.1 0.7 1.4 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Trypsin PF00089.26 PSC69228.1 - 4.1e-24 85.6 1.4 5.9e-24 85.1 1.4 1.3 1 0 0 1 1 1 1 Trypsin NOG1_N PF17835.1 PSC69229.1 - 3.7e-53 179.8 0.0 8.9e-53 178.5 0.0 1.7 1 0 0 1 1 1 1 NOG1 N-terminal helical domain NOGCT PF08155.11 PSC69229.1 - 7.8e-27 93.0 1.7 2e-26 91.7 1.7 1.7 1 0 0 1 1 1 1 NOGCT (NUC087) domain NOG1 PF06858.14 PSC69229.1 - 4.3e-26 90.5 0.1 8.1e-26 89.6 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 PSC69229.1 - 2.3e-18 66.4 0.0 4.1e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PSC69229.1 - 1.5e-10 40.8 0.0 2.7e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 PSC69229.1 - 0.001 19.2 0.0 1.5 8.8 0.0 2.6 1 1 1 2 2 2 2 Dynamin family AIG1 PF04548.16 PSC69229.1 - 0.0094 15.3 0.0 0.019 14.3 0.0 1.5 1 0 0 1 1 1 1 AIG1 family Roc PF08477.13 PSC69229.1 - 0.01 16.0 0.0 0.095 12.9 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 PSC69229.1 - 0.05 13.5 0.0 0.79 9.6 0.0 2.4 2 1 0 2 2 2 0 RsgA GTPase CDC45 PF02724.14 PSC69229.1 - 1.1 7.4 7.4 1.7 6.8 7.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Thioredoxin PF00085.20 PSC69231.1 - 2.2e-24 85.4 0.0 3e-24 85.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PSC69231.1 - 1.6e-08 35.0 0.0 1.5e-07 31.8 0.0 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 PSC69231.1 - 0.00015 21.9 0.5 0.00027 21.1 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like Thioredoxin_8 PF13905.6 PSC69231.1 - 0.00046 20.5 0.0 0.0092 16.3 0.0 2.0 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 PSC69231.1 - 0.00065 19.2 0.0 0.00083 18.8 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 PSC69231.1 - 0.0028 17.6 0.0 0.0038 17.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Phosducin PF02114.16 PSC69231.1 - 0.017 14.1 0.0 0.022 13.7 0.0 1.1 1 0 0 1 1 1 0 Phosducin TraF PF13728.6 PSC69231.1 - 0.018 14.9 0.0 0.029 14.2 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_6 PF13848.6 PSC69231.1 - 0.042 13.8 0.0 0.049 13.5 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain HyaE PF07449.11 PSC69231.1 - 0.16 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Metallophos PF00149.28 PSC69232.1 - 4.5e-08 33.8 0.1 1.6e-07 32.1 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 PSC69232.1 - 0.22 10.8 0.1 0.37 10.1 0.1 1.3 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily Amino_oxidase PF01593.24 PSC69233.1 - 1.7e-19 70.5 0.0 2.8e-19 69.7 0.0 1.4 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PSC69233.1 - 6.8e-13 48.6 0.2 1.9e-12 47.2 0.2 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 PSC69233.1 - 4.3e-07 29.4 1.4 4e-06 26.2 0.5 2.2 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 PSC69233.1 - 3.2e-06 27.0 1.7 3.5e-05 23.6 0.8 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PSC69233.1 - 7.9e-06 25.3 0.0 0.00016 21.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PSC69233.1 - 1.9e-05 24.0 0.1 3.4e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 PSC69233.1 - 0.00014 21.4 0.1 0.00023 20.7 0.1 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GDI PF00996.18 PSC69233.1 - 0.0034 16.0 0.1 0.38 9.2 0.0 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor FAD_binding_3 PF01494.19 PSC69233.1 - 0.0065 15.8 0.2 0.01 15.1 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain GIDA PF01134.22 PSC69233.1 - 0.01 15.0 0.0 0.035 13.2 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A HI0933_like PF03486.14 PSC69233.1 - 0.02 13.6 1.5 0.034 12.9 1.5 1.4 1 0 0 1 1 1 0 HI0933-like protein MCRA PF06100.11 PSC69233.1 - 0.046 12.5 0.0 0.085 11.6 0.0 1.4 1 0 0 1 1 1 0 MCRA family Pyr_redox_3 PF13738.6 PSC69233.1 - 0.051 12.8 0.3 0.083 12.1 0.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 PSC69233.1 - 0.29 10.1 0.7 0.54 9.3 0.7 1.4 1 0 0 1 1 1 0 Lycopene cyclase protein Peptidase_M11 PF05548.11 PSC69234.1 - 6.7e-21 74.7 2.6 1.1e-20 74.0 2.6 1.2 1 0 0 1 1 1 1 Gametolysin peptidase M11 TolA_bind_tri PF16331.5 PSC69234.1 - 0.00023 21.2 7.6 0.00023 21.2 7.6 4.5 3 2 0 4 4 4 1 TolA binding protein trimerisation Reprolysin_4 PF13583.6 PSC69234.1 - 0.16 11.6 0.5 0.35 10.5 0.5 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like YabA PF06156.13 PSC69234.1 - 0.35 11.5 0.0 0.35 11.5 0.0 3.8 3 1 0 3 3 3 0 Initiation control protein YabA Reprolysin_5 PF13688.6 PSC69234.1 - 0.64 10.1 3.1 0.93 9.6 1.1 2.2 1 1 1 2 2 2 0 Metallo-peptidase family M12 Leu_zip PF15294.6 PSC69234.1 - 0.82 9.1 16.3 0.67 9.4 0.0 3.0 2 1 0 3 3 3 0 Leucine zipper Mei5 PF10376.9 PSC69234.1 - 2.3 8.0 5.5 2.6 7.9 0.0 2.4 2 0 0 2 2 2 0 Double-strand recombination repair protein Fez1 PF06818.15 PSC69234.1 - 3.7 7.9 35.7 11 6.5 18.1 2.7 1 1 1 2 2 2 0 Fez1 Macoilin PF09726.9 PSC69234.1 - 6.2 5.3 20.2 0.49 8.9 0.1 2.1 2 0 0 2 2 2 0 Macoilin family CENP-H PF05837.12 PSC69234.1 - 8 6.9 36.0 4.1 7.8 0.7 4.3 4 0 0 4 4 4 0 Centromere protein H (CENP-H) Q_salvage PF10343.9 PSC69235.1 - 1.2e-18 67.7 0.0 1.7e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family Sulfotransfer_3 PF13469.6 PSC69236.1 - 2.4e-35 122.9 1.0 1.8e-34 120.0 0.1 2.7 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PSC69236.1 - 6.9e-09 35.6 0.0 4.9e-08 32.8 0.0 2.0 1 1 0 1 1 1 1 Sulfotransferase domain TPR_12 PF13424.6 PSC69236.1 - 0.00014 22.1 1.1 0.00014 22.1 1.1 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 PSC69236.1 - 0.013 16.1 6.5 0.013 16.1 6.5 6.8 5 1 1 6 6 6 0 Tetratricopeptide repeat TPR_20 PF14561.6 PSC69236.1 - 0.045 14.1 11.6 0.57 10.6 1.7 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 PSC69236.1 - 0.12 12.6 7.6 16 5.9 0.2 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat PAS_4 PF08448.10 PSC69236.1 - 2.8 8.2 11.5 5.2 7.4 0.1 4.8 5 0 0 5 5 5 0 PAS fold TPR_10 PF13374.6 PSC69236.1 - 3.5 7.6 14.9 1.7 8.6 0.2 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat GTP_EFTU PF00009.27 PSC69237.1 - 9.3e-49 165.6 0.0 2.1e-48 164.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Peptidase_M11 PF05548.11 PSC69237.1 - 1e-15 57.7 6.3 1.5e-13 50.6 6.3 2.4 1 1 0 1 1 1 1 Gametolysin peptidase M11 RAP PF08373.10 PSC69237.1 - 1.6e-14 53.7 0.0 3.2e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 RAP domain DNA_pol_A_exo1 PF01612.20 PSC69237.1 - 7.9e-14 51.7 0.0 1.7e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 3'-5' exonuclease EFG_C PF00679.24 PSC69237.1 - 3.6e-13 49.3 0.0 1.3e-12 47.5 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G C-terminus AAA PF00004.29 PSC69237.1 - 3.5e-07 30.7 0.0 9.3e-07 29.3 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 PSC69237.1 - 3.6e-07 30.2 0.0 0.00011 22.3 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_30 PF13604.6 PSC69237.1 - 3.4e-05 23.7 3.3 4.1e-05 23.4 0.2 2.8 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 PSC69237.1 - 4.9e-05 23.8 0.0 0.0012 19.2 0.0 3.5 2 0 0 2 2 1 1 AAA ATPase domain AAA_19 PF13245.6 PSC69237.1 - 6.4e-05 23.3 0.1 0.0022 18.3 0.1 2.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 PSC69237.1 - 0.00016 21.7 0.0 0.00038 20.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 PSC69237.1 - 0.00022 20.7 0.0 0.00052 19.5 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI FAST_1 PF06743.15 PSC69237.1 - 0.00022 21.1 0.1 0.13 12.2 0.0 4.2 4 0 0 4 4 4 1 FAST kinase-like protein, subdomain 1 AAA_22 PF13401.6 PSC69237.1 - 0.00028 21.2 0.0 0.0077 16.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain MTES_1575 PF18741.1 PSC69237.1 - 0.00036 20.6 0.0 0.00095 19.3 0.0 1.7 1 0 0 1 1 1 1 REase_MTES_1575 AAA_18 PF13238.6 PSC69237.1 - 0.00065 20.2 0.0 0.0018 18.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 PSC69237.1 - 0.0027 16.8 0.5 0.0053 15.9 0.5 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.6 PSC69237.1 - 0.0033 17.4 0.0 0.0081 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 PSC69237.1 - 0.0039 17.1 0.8 0.79 9.6 0.8 2.6 1 1 0 1 1 1 1 NTPase AAA_28 PF13521.6 PSC69237.1 - 0.0041 17.4 0.4 0.021 15.0 0.0 2.6 2 0 0 2 2 1 1 AAA domain AAA_24 PF13479.6 PSC69237.1 - 0.0066 16.2 0.0 0.013 15.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain GTP_EFTU_D2 PF03144.25 PSC69237.1 - 0.0067 16.8 3.6 0.0071 16.7 1.7 2.1 2 0 0 2 2 1 1 Elongation factor Tu domain 2 AAA_33 PF13671.6 PSC69237.1 - 0.011 15.9 0.7 0.2 11.8 0.0 3.1 3 0 0 3 3 3 0 AAA domain Reprolysin_4 PF13583.6 PSC69237.1 - 0.018 14.7 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like NACHT PF05729.12 PSC69237.1 - 0.031 14.2 0.0 0.11 12.4 0.0 2.0 1 0 0 1 1 1 0 NACHT domain Viral_helicase1 PF01443.18 PSC69237.1 - 0.041 13.6 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TniB PF05621.11 PSC69237.1 - 0.095 12.1 0.0 0.34 10.3 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein Reprolysin_5 PF13688.6 PSC69237.1 - 0.1 12.8 0.2 0.26 11.4 0.2 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12 AAA_11 PF13086.6 PSC69237.1 - 0.11 12.3 0.2 6 6.6 0.1 2.3 1 1 1 2 2 2 0 AAA domain KdpD PF02702.17 PSC69237.1 - 0.12 11.9 0.1 0.25 10.8 0.1 1.5 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain MobB PF03205.14 PSC69237.1 - 0.15 12.0 0.0 28 4.6 0.0 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.6 PSC69237.1 - 0.15 12.5 0.0 0.34 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain HTH_20 PF12840.7 PSC69237.1 - 0.94 9.6 12.4 0.67 10.1 0.7 4.6 3 0 0 3 3 3 0 Helix-turn-helix domain COPI_C PF06957.11 PSC69239.1 - 1.1 7.9 8.0 1.8 7.2 8.0 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus FYDLN_acid PF09538.10 PSC69239.1 - 4.1 8.1 12.2 8.6 7.1 12.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DNA_pol_phi PF04931.13 PSC69239.1 - 5.5 5.0 7.6 7.4 4.5 7.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi COPI_C PF06957.11 PSC69240.1 - 1.1 7.9 8.0 1.8 7.2 8.0 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus FYDLN_acid PF09538.10 PSC69240.1 - 4.1 8.1 12.2 8.6 7.1 12.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) DNA_pol_phi PF04931.13 PSC69240.1 - 5.5 5.0 7.6 7.4 4.5 7.6 1.1 1 0 0 1 1 1 0 DNA polymerase phi IF3_C PF00707.22 PSC69241.1 - 3.2e-30 103.9 0.5 6.3e-30 103.0 0.5 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain IF3_N PF05198.16 PSC69241.1 - 7.3e-22 77.4 0.1 1.4e-21 76.5 0.1 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain TFIIA PF03153.13 PSC69241.1 - 2.8 7.9 19.4 0.3 11.1 15.2 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3824 PF12868.7 PSC69241.1 - 4 8.1 15.5 0.12 13.1 8.8 1.9 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Mcl1_mid PF12341.8 PSC69242.1 - 1e-79 268.0 0.0 1.5e-79 267.4 0.0 1.3 1 0 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region ANAPC4_WD40 PF12894.7 PSC69242.1 - 6.2e-12 45.7 0.3 0.0027 18.0 0.0 5.0 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PSC69242.1 - 1.3e-08 35.3 3.0 0.27 12.2 0.1 6.5 6 1 0 6 6 6 2 WD domain, G-beta repeat Hira PF07569.11 PSC69242.1 - 0.17 11.6 0.2 39 3.9 0.0 3.2 2 1 1 3 3 3 0 TUP1-like enhancer of split SAWADEE PF16719.5 PSC69243.1 - 4.7e-24 85.0 0.7 8.1e-24 84.2 0.0 1.8 2 0 0 2 2 2 1 SAWADEE domain zf-HC5HC2H PF13771.6 PSC69243.1 - 3.8e-08 33.5 6.8 3.8e-08 33.5 6.8 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 PSC69243.1 - 1.5e-06 28.3 4.8 1.5e-06 28.3 4.8 2.4 3 0 0 3 3 3 1 PHD-zinc-finger like domain Agenet PF05641.12 PSC69243.1 - 0.0067 16.9 0.1 0.34 11.4 0.0 2.6 2 0 0 2 2 2 1 Agenet domain zf-ANAPC11 PF12861.7 PSC69243.1 - 0.057 13.5 4.4 0.13 12.3 4.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 PSC69243.1 - 0.26 11.6 7.2 1.1 9.6 7.2 2.1 1 0 0 1 1 1 0 RING-H2 zinc finger domain Fer2 PF00111.27 PSC69244.1 - 1.4e-10 41.0 0.4 3.6e-10 39.7 0.4 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer2_3 PF13085.6 PSC69244.1 - 0.072 13.1 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain SNF2_N PF00176.23 PSC69245.1 - 1.5e-42 145.6 0.0 2.4e-42 144.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain SAWADEE PF16719.5 PSC69245.1 - 9.6e-25 87.2 0.0 3e-24 85.6 0.0 1.9 1 0 0 1 1 1 1 SAWADEE domain Helicase_C PF00271.31 PSC69245.1 - 6.7e-16 58.6 0.0 5.3e-13 49.3 0.0 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Chromo PF00385.24 PSC69245.1 - 3.5e-14 52.5 0.0 5.1e-09 35.9 0.0 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain zf-HC5HC2H PF13771.6 PSC69245.1 - 8.7e-09 35.5 6.9 8.7e-09 35.5 6.9 3.2 4 0 0 4 4 4 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 PSC69245.1 - 6.5e-07 29.5 5.3 6.5e-07 29.5 5.3 2.6 3 1 0 3 3 3 1 PHD-zinc-finger like domain HDA2-3 PF11496.8 PSC69245.1 - 0.0029 16.8 0.1 0.0061 15.8 0.1 1.4 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Agenet PF05641.12 PSC69245.1 - 0.06 13.8 0.2 1.3 9.6 0.0 2.8 2 0 0 2 2 2 0 Agenet domain FKBP_C PF00254.28 PSC69246.1 - 1.4e-35 121.5 0.0 1.7e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Aminotran_4 PF01063.19 PSC69247.1 - 3.8e-36 125.0 0.0 5.3e-36 124.6 0.0 1.2 1 0 0 1 1 1 1 Amino-transferase class IV Sulfotransfer_3 PF13469.6 PSC69247.1 - 0.00013 22.5 0.1 0.002 18.5 0.1 2.4 2 1 0 2 2 2 1 Sulfotransferase family rve PF00665.26 PSC69248.1 - 1.5e-17 63.9 0.1 3.3e-17 62.8 0.0 1.7 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 PSC69248.1 - 0.0019 17.9 0.0 0.0051 16.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain PAS_4 PF08448.10 PSC69248.1 - 0.0033 17.7 0.2 0.054 13.7 0.0 2.6 2 0 0 2 2 2 1 PAS fold MRP_L53 PF10780.9 PSC69249.1 - 1e-11 44.8 0.0 1.6e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 UPF0240 PF06784.11 PSC69249.1 - 0.0018 18.4 0.1 0.0026 17.8 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0240) Ammonium_transp PF00909.21 PSC69250.1 - 9.5e-95 317.6 26.2 1.5e-94 317.0 26.2 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family Cu_bind_like PF02298.17 PSC69250.1 - 0.0032 17.4 0.0 0.0058 16.6 0.0 1.3 1 0 0 1 1 1 1 Plastocyanin-like domain MT-A70 PF05063.14 PSC69251.1 - 4e-33 114.8 0.0 8.5e-23 81.1 0.0 2.3 2 0 0 2 2 2 2 MT-A70 K_channel_TID PF07941.11 PSC69251.1 - 0.0041 17.5 10.7 0.0041 17.5 10.7 7.2 6 2 1 7 7 7 1 Potassium channel Kv1.4 tandem inactivation domain SRP-alpha_N PF04086.13 PSC69251.1 - 1.4 8.8 6.8 3.3 7.6 6.8 1.6 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal CBM_20 PF00686.19 PSC69252.1 - 1.3e-13 50.6 0.0 2.7e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Starch binding domain zf-MYND PF01753.18 PSC69252.1 - 6.3e-05 23.0 19.3 0.00011 22.2 19.3 1.4 1 0 0 1 1 1 1 MYND finger CBM_20 PF00686.19 PSC69253.1 - 1.4e-13 50.5 0.0 2.8e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Starch binding domain zf-MYND PF01753.18 PSC69253.1 - 7e-05 22.8 19.3 0.00012 22.1 19.3 1.4 1 0 0 1 1 1 1 MYND finger ABC_tran PF00005.27 PSC69255.1 - 1.2e-53 181.2 7.2 3.2e-27 95.7 0.1 3.9 4 1 0 4 4 3 2 ABC transporter ABC_tran_Xtn PF12848.7 PSC69255.1 - 1.2e-24 86.1 23.9 1.1e-19 70.3 2.9 3.3 3 0 0 3 3 3 2 ABC transporter AAA_21 PF13304.6 PSC69255.1 - 2.6e-14 53.8 8.1 0.00039 20.3 0.1 4.4 2 2 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PSC69255.1 - 4.6e-09 36.0 0.8 0.23 10.9 0.0 4.3 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PSC69255.1 - 2.8e-07 30.2 1.2 0.0007 19.3 0.0 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 PSC69255.1 - 4e-07 30.4 2.2 0.0044 17.3 0.0 3.5 2 2 1 3 3 3 2 AAA domain AAA_16 PF13191.6 PSC69255.1 - 5.5e-07 30.1 0.3 0.01 16.2 0.0 3.2 3 0 0 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 PSC69255.1 - 1.2e-05 25.3 0.9 0.0078 16.1 0.0 2.8 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 PSC69255.1 - 1.5e-05 24.8 5.7 0.025 14.3 0.1 3.7 3 1 0 3 3 3 2 AAA domain AAA_5 PF07728.14 PSC69255.1 - 7.1e-05 22.8 0.3 0.016 15.2 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_23 PF13476.6 PSC69255.1 - 7.2e-05 23.4 20.8 0.017 15.6 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_15 PF13175.6 PSC69255.1 - 0.0001 22.2 7.1 0.1 12.3 4.6 3.4 2 1 0 2 2 2 2 AAA ATPase domain cobW PF02492.19 PSC69255.1 - 0.00013 21.6 1.8 0.97 9.0 0.0 3.8 4 1 0 4 4 4 2 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 PSC69255.1 - 0.00015 21.9 0.2 0.45 10.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain ATP-synt_ab PF00006.25 PSC69255.1 - 0.00017 21.3 0.1 0.05 13.2 0.0 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain MMR_HSR1 PF01926.23 PSC69255.1 - 0.00028 20.9 6.5 0.015 15.4 1.1 3.6 2 2 0 2 2 2 1 50S ribosome-binding GTPase AAA_14 PF13173.6 PSC69255.1 - 0.00034 20.7 0.9 2.7 8.0 0.1 3.8 3 1 0 3 3 3 2 AAA domain Dynamin_N PF00350.23 PSC69255.1 - 0.00054 20.1 4.0 0.54 10.3 0.0 3.4 3 0 0 3 3 3 1 Dynamin family NACHT PF05729.12 PSC69255.1 - 0.00097 19.1 0.1 0.65 9.9 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_18 PF13238.6 PSC69255.1 - 0.0011 19.5 2.1 0.22 12.1 0.0 3.3 3 1 0 3 3 2 1 AAA domain AAA_28 PF13521.6 PSC69255.1 - 0.0019 18.5 2.1 0.072 13.3 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 PSC69255.1 - 0.0035 17.8 1.2 5.2 7.5 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 PSC69255.1 - 0.0087 15.6 0.1 1.3 8.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Arf PF00025.21 PSC69255.1 - 0.009 15.5 0.1 2.3 7.6 0.0 2.9 2 0 0 2 2 2 1 ADP-ribosylation factor family Thymidylate_kin PF02223.17 PSC69255.1 - 0.014 15.1 10.7 0.19 11.4 0.0 3.8 4 0 0 4 4 3 0 Thymidylate kinase AAA_24 PF13479.6 PSC69255.1 - 0.015 15.0 6.7 0.38 10.4 0.0 3.7 3 1 0 3 3 3 0 AAA domain TsaE PF02367.17 PSC69255.1 - 0.016 15.2 0.0 7.7 6.5 0.0 2.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NTPase_1 PF03266.15 PSC69255.1 - 0.022 14.7 8.7 15 5.4 0.1 4.9 4 1 1 5 5 5 0 NTPase Zeta_toxin PF06414.12 PSC69255.1 - 0.035 13.4 4.3 1.8 7.8 0.1 2.8 3 0 0 3 3 2 0 Zeta toxin IstB_IS21 PF01695.17 PSC69255.1 - 0.045 13.5 0.1 1.1 8.9 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein Barttin PF15462.6 PSC69255.1 - 0.063 13.0 0.0 0.063 13.0 0.0 1.8 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) AAA_25 PF13481.6 PSC69255.1 - 0.073 12.6 0.7 2 7.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain MukB PF04310.12 PSC69255.1 - 0.089 12.6 2.6 0.79 9.5 0.0 3.0 3 0 0 3 3 3 0 MukB N-terminal DUF87 PF01935.17 PSC69255.1 - 0.17 11.9 5.2 2.5 8.1 0.0 3.9 4 0 0 4 4 4 0 Helicase HerA, central domain AAA_27 PF13514.6 PSC69255.1 - 0.2 11.2 5.7 0.41 10.2 0.0 3.1 3 0 0 3 3 2 0 AAA domain Roc PF08477.13 PSC69255.1 - 0.3 11.3 0.0 0.3 11.3 0.0 3.3 4 0 0 4 4 2 0 Ras of Complex, Roc, domain of DAPkinase MeaB PF03308.16 PSC69255.1 - 0.34 9.9 7.3 0.38 9.7 0.0 2.9 4 0 0 4 4 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 PSC69255.1 - 0.53 9.9 4.9 11 5.5 2.4 3.1 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.18 PSC69255.1 - 4.5 6.5 5.8 21 4.3 0.0 3.3 4 0 0 4 4 4 0 FtsK/SpoIIIE family IMPDH PF00478.25 PSC69256.1 - 1.1e-122 409.4 6.8 1.5e-122 409.0 6.8 1.2 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain Cyclin_N PF00134.23 PSC69256.1 - 2.2e-14 53.3 0.0 6.4e-11 42.1 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain NMO PF03060.15 PSC69256.1 - 3e-11 43.3 6.6 1.5e-08 34.5 3.1 2.4 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 PSC69256.1 - 2.4e-09 36.7 2.3 6.5e-09 35.3 2.3 1.7 1 0 0 1 1 1 1 FMN-dependent dehydrogenase CBS PF00571.28 PSC69256.1 - 1.4e-05 25.5 0.0 0.16 12.5 0.0 2.6 2 0 0 2 2 2 2 CBS domain His_biosynth PF00977.21 PSC69256.1 - 1.9e-05 24.3 0.9 4.1e-05 23.2 0.9 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 PSC69256.1 - 0.00021 20.7 0.8 0.00021 20.7 0.8 1.9 2 0 0 2 2 1 1 Thiazole biosynthesis protein ThiG Cyclin_C_2 PF16899.5 PSC69256.1 - 0.0042 17.5 0.0 0.01 16.2 0.0 1.6 1 0 0 1 1 1 1 Cyclin C-terminal domain Cyclin_C PF02984.19 PSC69256.1 - 0.0052 16.9 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain B12-binding PF02310.19 PSC69256.1 - 0.0068 16.4 0.1 0.024 14.7 0.1 2.0 1 0 0 1 1 1 1 B12 binding domain IGPS PF00218.21 PSC69256.1 - 0.15 11.2 0.0 3.1 6.9 0.0 2.2 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Mito_carr PF00153.27 PSC69257.1 - 9.2e-28 96.0 5.7 8.9e-14 51.2 0.0 3.8 3 1 0 3 3 3 3 Mitochondrial carrier protein TT_ORF2 PF02957.15 PSC69258.1 - 0.71 10.8 3.4 1.9 9.4 3.4 1.7 1 0 0 1 1 1 0 TT viral ORF2 TFIIA PF03153.13 PSC69258.1 - 5.1 7.0 11.0 7.3 6.5 11.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TT_ORF2 PF02957.15 PSC69259.1 - 0.73 10.8 3.4 2 9.4 3.4 1.7 1 0 0 1 1 1 0 TT viral ORF2 TFIIA PF03153.13 PSC69259.1 - 5.3 6.9 11.0 7.5 6.4 11.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TP_methylase PF00590.20 PSC69260.1 - 1e-45 156.3 2.8 1e-45 156.3 2.8 1.4 2 0 0 2 2 2 1 Tetrapyrrole (Corrin/Porphyrin) Methylases SUIM_assoc PF16619.5 PSC69260.1 - 0.12 12.5 5.8 0.24 11.5 5.8 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF2477 PF10631.9 PSC69260.1 - 0.26 12.0 2.1 0.49 11.0 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2477) Spt20 PF12090.8 PSC69260.1 - 5.2 6.6 5.8 7.5 6.1 5.8 1.1 1 0 0 1 1 1 0 Spt20 family SWIM PF04434.17 PSC69261.1 - 6 6.6 10.9 1.4 8.6 3.2 2.8 2 0 0 2 2 2 0 SWIM zinc finger zf-HC5HC2H PF13771.6 PSC69263.1 - 4.8e-12 46.0 5.1 1.1e-11 44.8 5.1 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 PSC69263.1 - 1.1e-08 35.2 4.4 2.6e-08 34.0 4.4 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain SAND PF01342.21 PSC69263.1 - 8.3e-07 28.6 0.0 1.5e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 SAND domain CWC25 PF12542.8 PSC69264.1 - 5.7e-12 46.4 0.1 5.7e-12 46.4 0.1 5.1 5 1 0 5 5 5 1 Pre-mRNA splicing factor Cir_N PF10197.9 PSC69264.1 - 1.8e-10 40.8 12.5 1.8e-10 40.8 12.5 6.4 6 0 0 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR Mito_carr PF00153.27 PSC69265.1 - 1.8e-58 194.5 2.8 6.3e-22 77.3 0.1 3.3 2 1 1 3 3 3 3 Mitochondrial carrier protein PMT_2 PF13231.6 PSC69265.1 - 0.072 13.3 0.0 1.7 8.8 0.0 2.4 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase IRK_C PF17655.1 PSC69266.1 - 2.9e-29 101.9 0.0 6.6e-29 100.7 0.0 1.5 2 0 0 2 2 2 1 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 PSC69266.1 - 4.3e-16 59.0 5.4 2.1e-15 56.8 5.4 1.9 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain Ion_trans_2 PF07885.16 PSC69266.1 - 1.1e-06 28.5 2.8 2.1e-06 27.6 2.8 1.5 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 PSC69266.1 - 0.028 13.6 2.7 0.039 13.2 2.7 1.1 1 0 0 1 1 1 0 Ion transport protein EF-hand_1 PF00036.32 PSC69267.1 - 2.7e-20 70.3 0.3 1.8e-05 23.9 0.1 4.0 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 PSC69267.1 - 2.1e-17 63.3 0.1 1.3e-10 41.6 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PSC69267.1 - 9.2e-16 56.4 0.3 0.00016 21.4 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 PSC69267.1 - 2.3e-15 56.1 0.9 2.9e-08 33.4 0.0 3.1 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 PSC69267.1 - 9.5e-14 50.2 4.9 0.00091 18.6 0.3 4.2 4 0 0 4 4 4 3 EF hand EF-hand_9 PF14658.6 PSC69267.1 - 6.2e-05 23.2 0.1 0.0016 18.7 0.0 2.6 2 1 0 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 PSC69267.1 - 0.0021 18.0 0.4 0.15 12.0 0.0 2.4 1 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand Ipi1_N PF12333.8 PSC69268.1 - 2.3e-15 57.0 0.1 2.5e-12 47.3 0.0 3.7 3 0 0 3 3 3 2 Rix1 complex component involved in 60S ribosome maturation TFIIA PF03153.13 PSC69268.1 - 2 8.3 3.9 3.4 7.6 3.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RCC1 PF00415.18 PSC69269.1 - 4.3e-24 84.9 19.2 3.7e-10 40.3 0.8 7.1 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PSC69269.1 - 6.8e-19 67.2 21.4 0.0018 18.0 0.1 7.2 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Sulfotransfer_3 PF13469.6 PSC69269.1 - 0.00011 22.7 0.1 0.00011 22.7 0.1 4.7 4 1 0 4 4 4 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PSC69269.1 - 0.00085 18.9 0.5 0.0015 18.1 0.0 1.7 2 0 0 2 2 2 1 Sulfotransferase domain zf-U1 PF06220.12 PSC69270.1 - 3.8e-20 71.4 6.4 4.9e-20 71.0 6.4 1.2 1 0 0 1 1 1 1 U1 zinc finger CLIP1_ZNF PF16641.5 PSC69270.1 - 0.034 14.0 1.8 0.052 13.4 1.8 1.3 1 0 0 1 1 1 0 CLIP1 zinc knuckle Methyltr_RsmB-F PF01189.17 PSC69271.1 - 2.6e-49 167.6 0.0 2.1e-34 118.9 0.0 2.3 2 0 0 2 2 2 2 16S rRNA methyltransferase RsmB/F NusB PF01029.18 PSC69271.1 - 1.5e-18 67.3 0.1 3.5e-18 66.1 0.0 1.7 2 0 0 2 2 2 1 NusB family FtsJ PF01728.19 PSC69271.1 - 8.7e-05 22.7 0.0 0.00015 21.9 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 PSC69271.1 - 0.001 19.7 0.1 0.0035 18.0 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC69271.1 - 0.022 14.6 0.0 0.86 9.4 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain Ilar_coat PF01787.16 PSC69271.1 - 0.11 12.3 0.0 0.31 10.8 0.0 1.8 1 0 0 1 1 1 0 Ilarvirus coat protein Methyltransf_15 PF09445.10 PSC69271.1 - 0.23 11.0 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase GATA PF00320.27 PSC69272.1 - 0.29 10.8 5.2 0.091 12.4 2.1 1.8 2 0 0 2 2 2 0 GATA zinc finger TFIIA PF03153.13 PSC69272.1 - 2.9 7.8 21.5 1.6 8.6 6.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Med31 PF05669.12 PSC69273.1 - 4.5e-34 116.3 7.5 5.4e-34 116.1 7.5 1.0 1 0 0 1 1 1 1 SOH1 Pkinase_Tyr PF07714.17 PSC69274.1 - 1.7e-47 161.9 0.0 2.3e-46 158.2 0.0 2.4 2 1 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 PSC69274.1 - 8.4e-39 133.5 0.0 3.2e-38 131.6 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain RCC1_2 PF13540.6 PSC69274.1 - 1.9e-18 65.7 48.3 0.00018 21.2 2.4 6.8 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 PSC69274.1 - 1.7e-11 44.6 23.5 4.4e-05 24.0 0.1 6.5 6 0 0 6 6 6 3 Regulator of chromosome condensation (RCC1) repeat APH PF01636.23 PSC69274.1 - 0.00058 19.9 0.2 0.0011 18.9 0.2 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF2755 PF10954.8 PSC69274.1 - 0.13 12.2 0.4 0.98 9.4 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) DUF4598 PF15370.6 PSC69275.1 - 1.1e-12 48.3 0.0 1.6e-12 47.9 0.0 1.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4598) DUF4598 PF15370.6 PSC69276.1 - 1.7e-09 38.2 0.0 5.2e-09 36.6 0.0 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF4598) PsbQ PF05757.11 PSC69277.1 - 5.9e-46 156.7 11.2 5.9e-46 156.7 11.2 2.0 2 0 0 2 2 2 1 Oxygen evolving enhancer protein 3 (PsbQ) Ribosomal_L4 PF00573.22 PSC69277.1 - 6.3e-40 136.9 0.4 6.3e-40 136.9 0.4 2.7 3 0 0 3 3 3 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 PSC69277.1 - 1.9e-28 98.3 0.5 1.9e-28 98.3 0.5 2.4 2 0 0 2 2 2 1 60S ribosomal protein L4 C-terminal domain PsbW PF07123.12 PSC69277.1 - 1.9 8.5 4.8 1.1 9.3 1.7 2.2 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) Glyco_transf_90 PF05686.12 PSC69278.1 - 2.5e-32 112.3 0.1 3.8e-32 111.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 90 SelK_SelG PF10961.8 PSC69278.1 - 1.5 9.5 6.0 3.2 8.4 6.0 1.5 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Aa_trans PF01490.18 PSC69279.1 - 4.3e-76 256.2 22.3 5.8e-76 255.8 22.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PAP_fibrillin PF04755.12 PSC69279.1 - 4.7e-13 49.5 0.0 7.7e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 PAP_fibrillin Cytomega_UL20A PF05984.12 PSC69279.1 - 0.25 11.7 0.9 18 5.7 0.0 2.7 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein Aa_trans PF01490.18 PSC69280.1 - 4.2e-76 256.3 22.3 5.7e-76 255.9 22.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PAP_fibrillin PF04755.12 PSC69280.1 - 4.7e-13 49.5 0.0 7.6e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 PAP_fibrillin Cytomega_UL20A PF05984.12 PSC69280.1 - 0.24 11.7 0.9 18 5.7 0.0 2.7 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein Aa_trans PF01490.18 PSC69281.1 - 4.2e-76 256.3 22.3 5.8e-76 255.8 22.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PAP_fibrillin PF04755.12 PSC69281.1 - 4.7e-13 49.5 0.0 7.8e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 PAP_fibrillin Cytomega_UL20A PF05984.12 PSC69281.1 - 0.26 11.6 0.9 18 5.7 0.0 2.6 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein Aa_trans PF01490.18 PSC69282.1 - 4.3e-76 256.2 22.3 5.8e-76 255.8 22.3 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PAP_fibrillin PF04755.12 PSC69282.1 - 4.7e-13 49.5 0.0 7.8e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 PAP_fibrillin Cytomega_UL20A PF05984.12 PSC69282.1 - 0.23 11.8 0.9 18 5.7 0.0 2.7 2 0 0 2 2 2 0 Cytomegalovirus UL20A protein Gon7 PF08738.10 PSC69283.1 - 2.3 8.3 6.2 21 5.2 1.6 3.3 2 1 1 3 3 3 0 Gon7 family LRR_8 PF13855.6 PSC69284.1 - 1.3e-06 28.0 8.5 0.0061 16.3 0.8 4.2 2 1 2 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 PSC69284.1 - 1.1e-05 25.6 6.6 0.033 14.6 0.4 3.8 4 1 0 5 5 5 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 PSC69284.1 - 6.5e-05 22.8 1.7 6.5e-05 22.8 1.7 2.4 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.33 PSC69284.1 - 0.0045 17.3 12.7 0.58 10.9 0.0 5.9 5 2 0 5 5 5 1 Leucine Rich Repeat LRR_6 PF13516.6 PSC69284.1 - 0.068 13.3 12.3 11 6.4 0.0 5.6 5 0 0 5 5 5 0 Leucine Rich repeat F-box-like PF12937.7 PSC69285.1 - 6.3e-05 22.8 1.7 6.3e-05 22.8 1.7 2.5 2 0 0 2 2 2 1 F-box-like LRR_8 PF13855.6 PSC69285.1 - 0.00017 21.3 6.3 0.005 16.6 0.5 4.4 3 1 1 4 4 4 1 Leucine rich repeat LRR_4 PF12799.7 PSC69285.1 - 0.0002 21.6 4.7 0.0071 16.7 1.2 3.8 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PSC69285.1 - 0.00045 20.4 7.3 0.57 10.9 0.0 5.2 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 PSC69285.1 - 0.17 12.0 9.6 11 6.4 0.0 4.8 4 0 0 4 4 4 0 Leucine Rich repeat Trypsin PF00089.26 PSC69286.1 - 7e-23 81.6 0.2 8.7e-23 81.3 0.2 1.2 1 0 0 1 1 1 1 Trypsin Conotoxin PF02950.17 PSC69286.1 - 3.6 8.7 8.9 0.59 11.2 5.0 1.7 2 0 0 2 2 2 0 Conotoxin Pre-PUA PF17832.1 PSC69287.1 - 3.2e-24 85.4 0.0 4.7e-24 84.9 0.0 1.2 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 PSC69287.1 - 4.8e-18 64.9 0.4 7.1e-18 64.3 0.4 1.3 1 0 0 1 1 1 1 PUA domain zf-MYND PF01753.18 PSC69288.1 - 4.6e-07 29.8 18.8 7.8e-07 29.1 18.8 1.4 1 0 0 1 1 1 1 MYND finger DUF1336 PF07059.12 PSC69289.1 - 2.6e-47 161.8 0.0 3.2e-47 161.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) efThoc1 PF11957.8 PSC69290.1 - 4.3e-76 256.6 0.0 4.9e-75 253.1 0.0 1.9 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor efThoc1 PF11957.8 PSC69291.1 - 4.6e-76 256.5 0.0 9.6e-75 252.1 0.0 2.0 1 1 0 1 1 1 1 THO complex subunit 1 transcription elongation factor Cys_rich_FGFR PF00839.17 PSC69293.1 - 8.2e-79 259.7 63.2 7.9e-10 38.8 1.0 12.3 12 0 0 12 12 12 12 Cysteine rich repeat L27_1 PF09058.10 PSC69295.1 - 0.083 12.9 31.0 93 3.1 0.1 12.4 14 0 0 14 14 14 0 L27_1 Cyt-b5 PF00173.28 PSC69297.1 - 2.9e-21 75.4 0.0 4.1e-21 74.9 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FH2 PF02181.23 PSC69298.1 - 8.1e-47 160.1 0.0 4.5e-43 147.8 0.0 3.0 3 0 0 3 3 3 2 Formin Homology 2 Domain MID_pPIWI_RE PF18157.1 PSC69298.1 - 0.11 12.8 1.8 0.79 10.0 0.0 3.1 3 0 0 3 3 3 0 MID domain of pPIWI_RE Phage_TAC_2 PF06894.11 PSC69299.1 - 0.12 12.2 0.1 0.19 11.5 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage lambda tail assembly chaperone, TAC, protein G Peptidase_A22B PF04258.13 PSC69300.1 - 1e-54 186.0 1.4 6.6e-37 127.6 0.1 2.1 2 0 0 2 2 2 2 Signal peptide peptidase DIOX_N PF14226.6 PSC69301.1 - 2.1e-28 99.4 0.0 3.7e-28 98.7 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 PSC69301.1 - 3.4e-15 56.4 0.0 6.2e-15 55.5 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RPN13_C PF16550.5 PSC69302.1 - 9.8e-19 67.6 1.8 2.7e-18 66.2 0.1 2.7 2 0 0 2 2 2 1 UCH-binding domain GATA PF00320.27 PSC69302.1 - 2.2e-05 24.0 4.1 5.9e-05 22.6 4.1 1.7 1 0 0 1 1 1 1 GATA zinc finger zf-ribbon_3 PF13248.6 PSC69302.1 - 0.041 13.3 4.6 0.55 9.7 0.0 3.1 3 0 0 3 3 3 0 zinc-ribbon domain DUF5567 PF17722.1 PSC69302.1 - 0.17 11.7 3.4 0.31 10.9 3.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5567) Prim_Zn_Ribbon PF08273.12 PSC69302.1 - 5.5 7.4 9.8 0.57 10.5 2.0 2.4 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase LAP1C PF05609.12 PSC69302.1 - 6 5.8 13.7 12 4.8 13.7 1.4 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) NnrU PF07298.11 PSC69303.1 - 9.6e-51 172.3 7.7 1.5e-50 171.7 7.7 1.2 1 0 0 1 1 1 1 NnrU protein PEMT PF04191.13 PSC69303.1 - 0.00059 20.2 1.2 0.0012 19.3 0.2 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF3999 PF13163.6 PSC69303.1 - 0.001 18.4 0.1 0.0015 17.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3999) Spc7_N PF15402.6 PSC69303.1 - 1 7.5 1.7 1.4 7.1 1.7 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 HEAT PF02985.22 PSC69304.1 - 0.0068 16.6 14.1 0.24 11.8 0.1 5.2 4 0 0 4 4 4 2 HEAT repeat CmcI PF04989.12 PSC69306.1 - 8.8e-42 143.1 0.0 1.6e-41 142.2 0.0 1.5 1 0 0 1 1 1 1 Cephalosporin hydroxylase Methyltransf_24 PF13578.6 PSC69306.1 - 0.00025 22.0 0.0 0.0016 19.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain MRP-S32 PF10210.9 PSC69306.1 - 0.11 13.0 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 PAN_4 PF14295.6 PSC69307.1 - 8.3e-06 25.6 1.0 8.3e-06 25.6 1.0 3.7 4 0 0 4 4 4 1 PAN domain Gal_Lectin PF02140.18 PSC69307.1 - 2.2e-05 24.8 0.0 0.00015 22.1 0.0 2.5 1 1 0 1 1 1 1 Galactose binding lectin domain Myb_DNA-binding PF00249.31 PSC69308.1 - 2.1e-07 31.0 0.1 4.9e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain PHD PF00628.29 PSC69308.1 - 2.7e-07 30.4 4.3 4.5e-07 29.7 4.3 1.4 1 0 0 1 1 1 1 PHD-finger Myb_DNA-bind_6 PF13921.6 PSC69308.1 - 8.6e-05 22.7 0.0 0.00023 21.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain XRN_N PF03159.18 PSC69308.1 - 0.024 14.1 1.0 0.06 12.8 1.0 1.6 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Prok-RING_1 PF14446.6 PSC69308.1 - 0.076 13.0 3.0 0.17 11.8 3.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Myb_DNA-binding PF00249.31 PSC69309.1 - 2.1e-07 31.0 0.1 4.9e-07 29.8 0.1 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain PHD PF00628.29 PSC69309.1 - 2.7e-07 30.4 4.3 4.5e-07 29.7 4.3 1.4 1 0 0 1 1 1 1 PHD-finger Myb_DNA-bind_6 PF13921.6 PSC69309.1 - 8.4e-05 22.7 0.0 0.00023 21.3 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain XRN_N PF03159.18 PSC69309.1 - 0.024 14.1 1.0 0.059 12.8 1.0 1.6 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus Prok-RING_1 PF14446.6 PSC69309.1 - 0.076 13.0 3.0 0.17 11.8 3.0 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 APG6_N PF17675.1 PSC69310.1 - 0.02 15.4 3.9 0.028 14.9 3.9 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region DinB PF05163.12 PSC69310.1 - 0.035 14.0 0.2 0.047 13.6 0.2 1.2 1 0 0 1 1 1 0 DinB family JAKMIP_CC3 PF16034.5 PSC69310.1 - 0.052 13.5 1.1 0.07 13.1 1.1 1.1 1 0 0 1 1 1 0 JAKMIP CC3 domain DUF5560 PF17715.1 PSC69310.1 - 0.077 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5560) TM2 PF05154.16 PSC69310.1 - 0.11 12.9 2.5 0.32 11.4 2.5 1.8 1 0 0 1 1 1 0 TM2 domain YscO PF07321.12 PSC69310.1 - 0.14 12.1 8.9 0.21 11.6 8.9 1.1 1 0 0 1 1 1 0 Type III secretion protein YscO VIT1 PF01988.19 PSC69310.1 - 0.25 11.2 4.3 0.41 10.5 0.4 2.0 1 1 1 2 2 2 0 VIT family Hemerythrin PF01814.23 PSC69312.1 - 6.6e-12 46.2 14.4 6.6e-12 46.2 14.4 3.1 3 0 0 3 3 3 1 Hemerythrin HHE cation binding domain Lipase_GDSL_2 PF13472.6 PSC69312.1 - 1.2e-10 42.1 0.6 9.1e-10 39.2 0.2 2.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Pex24p PF06398.11 PSC69312.1 - 4.5e-09 35.8 0.2 6.6e-09 35.2 0.2 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin VASt PF16016.5 PSC69312.1 - 2.5e-07 31.2 0.0 3.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain DUF5372 PF17342.2 PSC69312.1 - 0.094 13.1 0.0 0.3 11.5 0.0 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5372) Acetyltransf_1 PF00583.25 PSC69313.1 - 3.6e-09 36.9 0.1 4.6e-09 36.5 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PSC69313.1 - 9.4e-07 28.8 0.1 1.2e-06 28.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PSC69313.1 - 2e-05 24.9 0.1 3.4e-05 24.2 0.1 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PSC69313.1 - 0.0067 16.5 0.2 0.013 15.6 0.2 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC69313.1 - 0.008 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Pkinase PF00069.25 PSC69314.1 - 1.3e-54 185.4 0.0 2.2e-54 184.6 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC69314.1 - 2.2e-20 73.1 0.0 1.8e-19 70.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Peptidase_C1 PF00112.23 PSC69314.1 - 3.5e-18 66.5 0.0 6.4e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Papain family cysteine protease PA14 PF07691.12 PSC69314.1 - 3.7e-11 43.0 0.0 7.2e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Haspin_kinase PF12330.8 PSC69314.1 - 0.11 11.4 0.0 0.19 10.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 PSC69315.1 - 1.1e-54 185.5 0.0 2e-54 184.7 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC69315.1 - 1.9e-20 73.2 0.0 1.7e-19 70.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Peptidase_C1 PF00112.23 PSC69315.1 - 1.5e-13 51.4 0.6 2.8e-13 50.5 0.6 1.4 1 0 0 1 1 1 1 Papain family cysteine protease PA14 PF07691.12 PSC69315.1 - 3.5e-11 43.1 0.0 6.7e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Haspin_kinase PF12330.8 PSC69315.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain NUDIX PF00293.28 PSC69316.1 - 1.5e-22 80.0 0.0 2.3e-22 79.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 PSC69316.1 - 8.8e-20 70.7 0.0 1.6e-19 69.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain SAM_2 PF07647.17 PSC69317.1 - 1.3e-13 50.8 0.0 2.5e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PSC69317.1 - 2.4e-12 47.1 0.0 3.9e-12 46.4 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 PSC69317.1 - 0.025 14.5 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain Polyketide_cyc PF03364.20 PSC69318.1 - 9.1e-22 77.7 1.0 1.9e-21 76.6 1.0 1.6 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport LRR_8 PF13855.6 PSC69318.1 - 3.1e-10 39.6 20.7 1.3e-07 31.3 1.7 8.0 6 3 1 7 7 7 1 Leucine rich repeat LRR_4 PF12799.7 PSC69318.1 - 7e-09 35.8 15.1 0.002 18.5 0.2 7.1 6 1 1 7 7 7 2 Leucine Rich repeats (2 copies) Polyketide_cyc2 PF10604.9 PSC69318.1 - 0.00031 21.0 0.2 0.00057 20.2 0.2 1.4 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport F-box-like PF12937.7 PSC69318.1 - 0.00091 19.1 0.3 0.52 10.3 0.1 2.8 2 0 0 2 2 2 2 F-box-like F-box PF00646.33 PSC69318.1 - 0.0019 18.0 0.0 1.3 9.0 0.0 3.0 2 0 0 2 2 2 2 F-box domain LRR_1 PF00560.33 PSC69318.1 - 0.0032 17.8 17.5 2.8 8.8 0.1 7.6 6 2 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 PSC69318.1 - 0.072 13.2 23.8 0.62 10.3 0.2 8.0 8 0 0 8 8 8 0 Leucine Rich repeat Peptidase_M54 PF07998.11 PSC69319.1 - 3.7e-15 56.4 0.0 5.2e-15 56.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M54 Peptidase_M10 PF00413.24 PSC69319.1 - 0.002 18.0 0.0 0.0037 17.1 0.0 1.4 1 0 0 1 1 1 1 Matrixin TFIIA PF03153.13 PSC69319.1 - 0.03 14.3 34.9 0.31 11.0 16.9 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Peptidase_M43 PF05572.13 PSC69319.1 - 0.076 12.9 0.1 0.13 12.2 0.1 1.2 1 0 0 1 1 1 0 Pregnancy-associated plasma protein-A DUF3292 PF11696.8 PSC69319.1 - 0.081 11.3 0.0 0.081 11.3 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3292) Peptidase_M66 PF10462.9 PSC69319.1 - 0.13 11.1 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Peptidase M66 DLIC PF05783.11 PSC69319.1 - 2.3 6.9 5.6 6.8 5.4 5.6 1.8 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) Metallopep PF12044.8 PSC69319.1 - 7.6 5.0 9.1 0.062 11.9 0.7 1.6 2 0 0 2 2 2 0 Putative peptidase family Lectin_N PF03954.14 PSC69320.1 - 0.062 13.0 0.5 0.25 11.1 0.6 1.9 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain TMPIT PF07851.13 PSC69321.1 - 3.6e-51 174.4 0.1 5.1e-51 173.8 0.1 1.2 1 0 0 1 1 1 1 TMPIT-like protein TMPIT PF07851.13 PSC69322.1 - 3.6e-51 174.4 0.1 5e-51 173.9 0.1 1.2 1 0 0 1 1 1 1 TMPIT-like protein WD40 PF00400.32 PSC69324.1 - 1.9e-16 60.2 0.7 0.00077 20.2 0.0 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC69324.1 - 6e-06 26.5 0.0 0.13 12.6 0.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Lactonase PF10282.9 PSC69324.1 - 0.15 11.3 0.0 0.35 10.1 0.0 1.5 1 0 0 1 1 1 0 Lactonase, 7-bladed beta-propeller FHA PF00498.26 PSC69325.1 - 4.2e-17 62.3 0.0 5.5e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 PSC69325.1 - 1.5e-14 54.1 0.0 2.3e-14 53.4 0.0 1.3 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Retrotran_gag_2 PF14223.6 PSC69326.1 - 3.2e-25 88.4 0.0 4.4e-25 88.0 0.0 1.1 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 PSC69326.1 - 1.1e-05 24.9 0.0 2e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 PSC69326.1 - 0.03 14.1 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type zf-CCHC_3 PF13917.6 PSC69326.1 - 0.032 14.2 0.3 0.084 12.9 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 PSC69326.1 - 0.036 13.8 2.0 0.067 12.9 2.0 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_5 PF14787.6 PSC69326.1 - 0.084 12.6 2.5 0.21 11.3 2.5 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Chloroa_b-bind PF00504.21 PSC69327.1 - 7.1e-36 124.2 0.4 2.3e-35 122.5 0.1 1.9 2 0 0 2 2 2 1 Chlorophyll A-B binding protein LRR_8 PF13855.6 PSC69327.1 - 3.2e-06 26.8 0.0 3.6e-05 23.4 0.0 2.9 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 PSC69327.1 - 0.0044 17.4 0.3 0.19 12.2 0.0 3.9 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) FIST_C PF10442.9 PSC69328.1 - 1.4e-05 25.0 2.8 0.00023 21.1 0.3 2.5 2 0 0 2 2 2 2 FIST C domain Aldedh PF00171.22 PSC69329.1 - 1.4e-180 600.8 0.0 1.5e-180 600.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Ribosomal_L37e PF01907.19 PSC69330.1 - 4.6e-27 93.9 8.4 8.4e-27 93.1 8.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e HypA PF01155.19 PSC69330.1 - 0.024 14.7 0.2 0.03 14.3 0.2 1.2 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DZR PF12773.7 PSC69330.1 - 0.024 14.7 2.0 0.034 14.2 2.0 1.3 1 0 0 1 1 1 0 Double zinc ribbon Sec6 PF06046.13 PSC69331.1 - 6.8e-73 245.9 0.0 1.1e-72 245.3 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec6 AIP3 PF03915.13 PSC69331.1 - 0.055 12.6 0.5 0.087 11.9 0.5 1.3 1 0 0 1 1 1 0 Actin interacting protein 3 ADIP PF11559.8 PSC69331.1 - 0.18 11.9 3.7 0.39 10.8 3.7 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Vps53_N PF04100.12 PSC69331.1 - 0.3 10.0 2.2 0.47 9.4 1.3 1.7 2 0 0 2 2 2 0 Vps53-like, N-terminal BAG PF02179.16 PSC69331.1 - 0.52 10.8 2.0 1.8 9.1 0.2 2.9 4 0 0 4 4 4 0 BAG domain TipAS PF07739.13 PSC69331.1 - 0.53 10.8 3.5 15 6.2 0.1 3.5 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain KH_1 PF00013.29 PSC69332.1 - 1.1e-28 98.8 0.0 6.9e-09 35.4 0.0 3.4 3 0 0 3 3 3 3 KH domain LRR_8 PF13855.6 PSC69332.1 - 1.4e-06 27.9 0.0 2.6e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 PSC69332.1 - 1.9e-06 28.1 0.0 9.7e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) KH_2 PF07650.17 PSC69332.1 - 1.8e-05 24.5 0.0 0.68 9.8 0.0 3.2 3 0 0 3 3 3 2 KH domain LRR_1 PF00560.33 PSC69332.1 - 0.00026 21.1 0.0 0.88 10.4 0.0 3.2 3 0 0 3 3 3 2 Leucine Rich Repeat LRRNT_2 PF08263.12 PSC69332.1 - 0.01 16.1 0.4 0.01 16.1 0.4 1.7 2 0 0 2 2 1 0 Leucine rich repeat N-terminal domain KH_4 PF13083.6 PSC69332.1 - 0.034 14.0 0.0 2.7 7.9 0.0 3.1 3 0 0 3 3 3 0 KH domain DotD PF16816.5 PSC69332.1 - 0.053 13.5 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 DotD protein KH_5 PF13184.6 PSC69332.1 - 0.066 13.3 1.0 18 5.5 0.0 3.4 3 1 0 3 3 3 0 NusA-like KH domain DUF4407 PF14362.6 PSC69332.1 - 0.19 11.1 2.2 0.32 10.3 2.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Collectrin PF16959.5 PSC69332.1 - 0.19 11.5 0.1 0.34 10.7 0.1 1.4 1 0 0 1 1 1 0 Renal amino acid transporter LRR_6 PF13516.6 PSC69332.1 - 0.2 11.8 3.1 4 7.7 0.1 3.8 4 0 0 4 4 4 0 Leucine Rich repeat GIT1_C PF12205.8 PSC69332.1 - 0.2 11.8 0.1 0.66 10.1 0.0 1.8 2 0 0 2 2 2 0 G protein-coupled receptor kinase-interacting protein 1 C term FeoB_associated PF12669.7 PSC69332.1 - 0.22 11.9 1.8 0.62 10.5 1.8 1.7 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein SLC35F PF06027.12 PSC69334.1 - 3.3e-76 256.7 3.1 3.9e-76 256.4 3.1 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 PSC69334.1 - 3.5e-10 39.4 0.0 4.9e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 PSC69334.1 - 0.00015 21.9 12.2 0.00015 21.9 12.2 2.9 2 1 0 2 2 2 1 EamA-like transporter family Mg_trans_NIPA PF05653.14 PSC69334.1 - 0.0012 18.1 2.7 0.0021 17.2 2.7 1.4 1 0 0 1 1 1 1 Magnesium transporter NIPA Glyco_transf_92 PF01697.27 PSC69336.1 - 6e-20 72.0 0.0 9.3e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 PAP2 PF01569.21 PSC69336.1 - 1.1e-12 47.9 8.6 7.2e-11 42.0 0.3 3.2 3 0 0 3 3 3 2 PAP2 superfamily Glyco_tranf_2_4 PF13704.6 PSC69336.1 - 8.5e-12 45.4 0.0 1.9e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 S_locus_glycop PF00954.20 PSC69336.1 - 0.019 15.5 0.3 0.042 14.4 0.3 1.6 1 0 0 1 1 1 0 S-locus glycoprotein domain Pkinase PF00069.25 PSC69337.1 - 2.9e-14 53.1 0.0 2.4e-10 40.2 0.0 2.4 2 1 0 2 2 2 2 Protein kinase domain Pkinase_fungal PF17667.1 PSC69337.1 - 0.062 12.1 0.0 0.082 11.7 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 PSC69337.1 - 0.089 12.7 0.1 0.089 12.7 0.1 2.8 3 0 0 3 3 3 0 Phosphotransferase enzyme family NIF PF03031.18 PSC69338.1 - 5e-54 182.3 0.1 7e-54 181.8 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase NicO PF03824.16 PSC69338.1 - 1.1 8.6 2.7 1.8 7.8 2.7 1.3 1 0 0 1 1 1 0 High-affinity nickel-transport protein Peptidase_S8 PF00082.22 PSC69339.1 - 2.5e-28 99.2 8.3 7.4e-28 97.7 8.3 1.8 1 0 0 1 1 1 1 Subtilase family Inhibitor_I9 PF05922.16 PSC69339.1 - 0.18 12.5 0.0 0.52 11.0 0.0 1.9 1 1 0 1 1 1 0 Peptidase inhibitor I9 PPC PF04151.15 PSC69339.1 - 1.8 9.7 7.8 3.9 8.6 0.8 3.5 3 0 0 3 3 3 0 Bacterial pre-peptidase C-terminal domain Peptidase_M20 PF01546.28 PSC69340.1 - 8.4e-31 107.3 0.0 2e-30 106.1 0.0 1.6 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PSC69340.1 - 3.1e-09 36.7 0.0 6.9e-09 35.6 0.0 1.6 1 1 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 PSC69340.1 - 0.045 13.4 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 Peptidase family M28 F-box PF00646.33 PSC69341.1 - 0.0005 19.9 0.0 0.001 18.9 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PSC69341.1 - 0.0055 16.6 0.0 0.015 15.2 0.0 1.8 1 0 0 1 1 1 1 F-box-like His_Phos_1 PF00300.22 PSC69342.1 - 4.5e-14 52.6 1.5 1.3e-08 34.8 0.1 2.2 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) AAA PF00004.29 PSC69343.1 - 1.3e-41 142.1 0.0 2.8e-41 141.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TauD PF02668.16 PSC69343.1 - 8.8e-29 101.1 0.1 1.4e-28 100.4 0.1 1.3 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family AAA_lid_3 PF17862.1 PSC69343.1 - 3.1e-14 52.5 0.2 8.4e-14 51.1 0.2 1.8 1 0 0 1 1 1 1 AAA+ lid domain Prot_ATP_ID_OB PF16450.5 PSC69343.1 - 1.9e-05 24.5 0.5 4.7e-05 23.3 0.5 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_2 PF07724.14 PSC69343.1 - 3e-05 24.2 0.0 8.4e-05 22.7 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 PSC69343.1 - 0.00011 22.2 0.0 0.00032 20.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PSC69343.1 - 0.00014 22.3 3.7 0.00047 20.6 0.0 3.4 2 1 0 3 3 3 1 AAA ATPase domain RuvB_N PF05496.12 PSC69343.1 - 0.00061 19.6 0.0 0.0014 18.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PSC69343.1 - 0.0023 18.2 0.2 0.048 13.9 0.0 2.6 1 1 1 2 2 2 1 AAA domain IstB_IS21 PF01695.17 PSC69343.1 - 0.0091 15.7 0.0 0.028 14.2 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 PSC69343.1 - 0.01 16.0 0.0 0.028 14.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PSC69343.1 - 0.025 15.1 0.0 0.065 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 PSC69343.1 - 0.026 13.7 0.0 0.044 13.0 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 PSC69343.1 - 0.034 13.5 0.1 0.068 12.5 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 PSC69343.1 - 0.037 13.9 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 PSC69343.1 - 0.059 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 PSC69343.1 - 0.064 12.7 0.0 0.51 9.8 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 PSC69343.1 - 0.074 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 KaiC DUF2072 PF09845.9 PSC69343.1 - 0.086 13.1 0.3 0.2 11.9 0.3 1.5 1 0 0 1 1 1 0 Zn-ribbon containing protein TsaE PF02367.17 PSC69343.1 - 0.12 12.4 0.0 0.25 11.3 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 PSC69343.1 - 0.13 11.9 0.0 0.26 11.0 0.0 1.5 1 1 0 1 1 1 0 AAA domain RILP PF11461.8 PSC69343.1 - 0.14 12.4 0.7 0.36 11.1 0.7 1.6 1 0 0 1 1 1 0 Rab interacting lysosomal protein Sigma54_activat PF00158.26 PSC69343.1 - 0.17 11.6 0.0 0.46 10.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 PSC69343.1 - 0.19 10.8 0.0 0.3 10.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 PSC69343.1 - 0.2 11.2 0.0 0.37 10.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Peptidase_U32 PF01136.19 PSC69344.1 - 3.9e-84 281.5 0.0 7.5e-73 244.5 0.0 2.4 2 0 0 2 2 2 2 Peptidase family U32 DUF3656 PF12392.8 PSC69344.1 - 1.3e-08 35.4 0.0 2.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Collagenase DUF1002 PF06207.11 PSC69345.1 - 0.2 11.1 0.0 0.22 11.0 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) PAP_fibrillin PF04755.12 PSC69346.1 - 7.1e-13 48.9 0.0 5.6e-10 39.5 0.0 3.0 1 1 0 1 1 1 1 PAP_fibrillin DUF4245 PF14030.6 PSC69346.1 - 0.0022 18.0 0.2 0.003 17.6 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4245) Alpha-amylase_C PF02806.18 PSC69348.1 - 6e-20 71.5 0.0 1.4e-19 70.3 0.0 1.7 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 PSC69348.1 - 4e-14 52.9 0.0 5.2e-09 36.1 0.0 2.2 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 PSC69348.1 - 7.6e-12 45.4 0.0 2e-11 44.1 0.0 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Glyco_hydro_66 PF13199.6 PSC69348.1 - 0.0032 16.2 0.0 0.0049 15.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 66 hDGE_amylase PF14701.6 PSC69348.1 - 0.11 11.6 0.1 0.21 10.6 0.1 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain Chloroa_b-bind PF00504.21 PSC69349.1 - 5.1e-39 134.4 1.6 5.1e-39 134.4 1.6 2.2 2 0 0 2 2 2 1 Chlorophyll A-B binding protein RSN1_7TM PF02714.15 PSC69350.1 - 3.5e-77 259.4 38.4 4.6e-40 137.7 9.9 3.2 3 0 0 3 3 3 3 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 PSC69350.1 - 1.2e-32 112.8 1.5 4.6e-32 110.9 1.5 2.1 1 0 0 1 1 1 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 PSC69350.1 - 2.5e-10 40.8 0.1 4.1e-10 40.2 0.1 1.3 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter DUF5368 PF17336.2 PSC69350.1 - 0.0032 17.6 0.7 43 4.3 0.0 4.0 3 0 0 3 3 3 0 Family of unknown function (DUF5368) DivIC PF04977.15 PSC69350.1 - 0.42 10.4 1.1 1.1 9.1 1.1 1.6 1 0 0 1 1 1 0 Septum formation initiator rve PF00665.26 PSC69351.1 - 1.2e-18 67.5 0.0 3.2e-18 66.0 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain zf_CCCH_4 PF18345.1 PSC69351.1 - 0.00025 21.0 7.3 0.00047 20.1 7.3 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 PSC69351.1 - 0.00037 20.3 1.1 0.00078 19.3 1.1 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) rve_3 PF13683.6 PSC69351.1 - 0.011 15.5 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Methyltransf_23 PF13489.6 PSC69351.1 - 0.023 14.5 0.1 0.045 13.6 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 PSC69351.1 - 0.027 14.4 4.0 0.26 11.3 4.0 2.5 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 PSC69351.1 - 0.043 13.1 0.0 0.081 12.2 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family zf-CCCH_4 PF18044.1 PSC69351.1 - 0.55 10.1 8.4 1.4 8.9 5.3 2.3 2 0 0 2 2 2 0 CCCH-type zinc finger Torus PF16131.5 PSC69351.1 - 0.73 10.6 8.6 0.25 12.0 0.9 2.7 3 0 0 3 3 2 0 Torus domain zf-CCCH_2 PF14608.6 PSC69351.1 - 1.7 9.2 3.4 5.4 7.6 3.4 1.9 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger eIF-3_zeta PF05091.12 PSC69351.1 - 2.2 7.2 5.9 3.2 6.6 5.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Tox-HNH-HHH PF15637.6 PSC69352.1 - 0.071 13.3 0.0 4.7 7.4 0.0 2.2 2 0 0 2 2 2 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif Lipase_3 PF01764.25 PSC69353.1 - 1.5e-18 67.0 0.0 1e-17 64.3 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 3) Cytochrom_B561 PF03188.16 PSC69353.1 - 1.2e-11 44.9 5.8 2.2e-11 44.0 5.8 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 PSC69353.1 - 0.017 14.9 0.3 0.058 13.2 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) Lipase_3 PF01764.25 PSC69354.1 - 1.4e-18 67.1 0.0 9.8e-18 64.4 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 3) Cytochrom_B561 PF03188.16 PSC69354.1 - 1.2e-11 44.9 5.8 2.1e-11 44.1 5.8 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 PSC69354.1 - 0.017 14.9 0.3 0.056 13.2 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF2427) tRNA_int_end_N2 PF12928.7 PSC69355.1 - 8.5e-10 38.7 0.2 1.8e-09 37.7 0.2 1.6 1 0 0 1 1 1 1 tRNA-splicing endonuclease subunit sen54 N-term tRNA_int_endo_N PF02778.14 PSC69355.1 - 0.086 12.5 0.4 0.17 11.6 0.4 1.4 1 0 0 1 1 1 0 tRNA intron endonuclease, N-terminal domain TFIIA PF03153.13 PSC69355.1 - 0.23 11.4 5.8 0.31 11.0 5.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pyr_redox_2 PF07992.14 PSC69356.1 - 7.8e-42 143.5 0.1 9.3e-42 143.2 0.1 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PSC69356.1 - 7.9e-09 36.0 0.8 3.6e-08 33.8 0.2 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PSC69356.1 - 0.071 12.3 0.0 2.3 7.4 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase SH2_2 PF14633.6 PSC69358.1 - 2e-49 167.9 0.0 5e-49 166.6 0.0 1.7 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.6 PSC69358.1 - 1.4e-14 54.2 0.0 2.7e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif SPT6_acidic PF14632.6 PSC69358.1 - 6.2e-14 52.4 21.4 6.2e-14 52.4 21.4 5.4 5 2 2 7 7 7 1 Acidic N-terminal SPT6 YqgF PF14639.6 PSC69358.1 - 7.3e-10 38.8 0.0 2.4e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 Holliday-junction resolvase-like of SPT6 Tex_N PF09371.10 PSC69358.1 - 3.6e-06 26.8 3.7 0.0001 22.1 0.0 3.2 4 0 0 4 4 4 1 Tex-like protein N-terminal domain HHH_9 PF17674.1 PSC69358.1 - 6.5e-05 23.8 0.7 0.00036 21.4 0.0 2.8 2 0 0 2 2 2 1 HHH domain HTH_44 PF14641.6 PSC69358.1 - 9.5e-05 22.8 0.0 0.00036 20.9 0.0 1.9 1 1 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 SpoIIE PF07228.12 PSC69359.1 - 1.4e-10 41.4 1.2 2.4e-10 40.7 0.0 1.8 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 PSC69359.1 - 7.7e-07 29.0 0.1 0.043 13.4 0.0 2.2 1 1 0 2 2 2 2 Protein phosphatase 2C Med21 PF11221.8 PSC69359.1 - 1.4e-06 28.6 1.3 4.6e-06 26.9 1.3 1.8 1 1 0 1 1 1 1 Subunit 21 of Mediator complex Hydrolase_like PF13242.6 PSC69360.1 - 1.6e-15 56.9 0.3 3.8e-15 55.7 0.3 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase_6 PF13344.6 PSC69360.1 - 2.2e-15 56.6 0.0 3.1e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PSC69360.1 - 2.9e-06 27.5 0.0 0.0002 21.5 0.0 2.1 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PSC69360.1 - 5.1e-05 23.6 0.2 0.019 15.3 0.1 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase TRAM_LAG1_CLN8 PF03798.16 PSC69361.1 - 3.6e-27 95.4 9.0 4.3e-27 95.1 9.0 1.1 1 0 0 1 1 1 1 TLC domain LRR_8 PF13855.6 PSC69362.1 - 2.8e-29 100.6 8.1 0.0001 22.0 0.1 8.2 2 2 6 9 9 9 9 Leucine rich repeat LRR_4 PF12799.7 PSC69362.1 - 4.8e-19 68.1 0.3 0.031 14.7 0.1 8.7 7 2 2 10 10 10 6 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 PSC69362.1 - 3.3e-16 59.3 8.3 2.5e-07 30.9 0.0 3.8 3 1 1 4 4 4 2 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 PSC69362.1 - 2e-07 30.6 0.3 43 5.2 0.0 8.3 9 0 0 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 PSC69362.1 - 0.024 14.7 15.2 66 3.9 0.0 9.4 12 0 0 12 12 12 0 Leucine Rich repeat PBP PF01161.20 PSC69363.1 - 1e-14 55.0 0.0 1.9e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein DnaJ_CXXCXGXG PF00684.19 PSC69364.1 - 7.2e-05 23.1 12.7 0.00034 20.9 13.0 2.1 1 1 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 PSC69364.1 - 0.0083 16.1 2.2 0.0083 16.1 2.2 3.0 1 1 2 3 3 3 1 Tryptophan RNA-binding attenuator protein inhibitory protein TAT_signal PF10518.9 PSC69364.1 - 0.0099 15.7 9.5 0.0099 15.7 9.5 3.3 4 0 0 4 4 4 1 TAT (twin-arginine translocation) pathway signal sequence Pex14_N PF04695.13 PSC69364.1 - 0.12 13.1 5.4 0.23 12.1 5.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Prim_Zn_Ribbon PF08273.12 PSC69364.1 - 5.2 7.4 17.3 8.5 6.8 12.9 3.0 1 1 1 2 2 2 0 Zinc-binding domain of primase-helicase B56 PF01603.20 PSC69365.1 - 1.2e-13 50.9 0.1 1.9e-12 46.9 0.0 2.5 1 1 1 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) CBM_20 PF00686.19 PSC69365.1 - 4.8e-12 45.6 0.0 1e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain B56 PF01603.20 PSC69366.1 - 1.3e-13 50.8 0.1 1.9e-12 46.9 0.0 2.5 1 1 1 2 2 2 2 Protein phosphatase 2A regulatory B subunit (B56 family) CBM_20 PF00686.19 PSC69366.1 - 4.9e-12 45.6 0.0 1e-11 44.5 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain Aa_trans PF01490.18 PSC69367.1 - 3.3e-23 82.1 17.6 5.2e-23 81.4 17.6 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein TPH PF13868.6 PSC69368.1 - 1.3e-08 33.7 115.7 1.3e-08 33.7 115.7 2.2 1 1 1 2 2 2 1 Trichohyalin-plectin-homology domain E1-E2_ATPase PF00122.20 PSC69369.1 - 6.1e-50 169.2 0.2 1.3e-49 168.1 0.2 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 PSC69369.1 - 1.7e-31 110.2 8.4 1.4e-30 107.1 8.4 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 PSC69369.1 - 4e-26 91.2 0.0 1.3e-12 47.9 0.0 2.5 2 0 0 2 2 2 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 PSC69369.1 - 0.00082 19.2 0.3 0.0013 18.6 0.3 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PSC69369.1 - 0.00095 19.6 0.3 0.03 14.7 0.1 2.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ArgJ PF01960.18 PSC69371.1 - 8.8e-53 179.4 0.0 1.3e-52 178.8 0.0 1.1 1 0 0 1 1 1 1 ArgJ family Herpes_gE PF02480.16 PSC69371.1 - 0.6 8.8 0.0 0.6 8.8 0.0 2.0 3 0 0 3 3 3 0 Alphaherpesvirus glycoprotein E Mitofilin PF09731.9 PSC69371.1 - 0.99 8.2 22.1 1.7 7.4 22.1 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SRP-alpha_N PF04086.13 PSC69371.1 - 2.2 8.1 19.8 3 7.7 19.8 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal GAGA_bind PF06217.12 PSC69371.1 - 2.5 8.3 14.2 5 7.3 14.2 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family DnaJ PF00226.31 PSC69372.1 - 8.2e-22 77.1 0.8 1.5e-21 76.3 0.8 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 PSC69372.1 - 2e-11 44.2 0.0 4e-11 43.2 0.0 1.6 1 1 0 1 1 1 1 DnaJ C terminal domain CDV3 PF15359.6 PSC69372.1 - 0.14 12.7 1.5 0.27 11.7 1.5 1.4 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 GYD PF08734.11 PSC69372.1 - 0.88 9.6 3.8 2.1 8.3 0.0 3.4 4 0 0 4 4 4 0 GYD domain CBM_20 PF00686.19 PSC69373.1 - 1.4e-13 50.6 0.0 2.6e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Starch binding domain DUF2052 PF09747.9 PSC69373.1 - 6.6 6.8 14.6 0.73 9.9 4.2 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Smg8_Smg9 PF10220.9 PSC69374.1 - 1.3e-26 93.3 0.0 1.4e-16 60.1 0.0 3.1 3 0 0 3 3 3 3 Smg8_Smg9 rve PF00665.26 PSC69374.1 - 0.092 12.9 0.0 0.24 11.6 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain XPG_I PF00867.18 PSC69375.1 - 1.7e-14 53.9 0.1 6.4e-14 52.1 0.0 1.9 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 PSC69375.1 - 1.5e-08 35.0 0.0 3e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain GYF PF02213.16 PSC69375.1 - 0.0011 18.6 0.7 0.002 17.8 0.7 1.5 1 0 0 1 1 1 1 GYF domain XPG_I_2 PF12813.7 PSC69375.1 - 0.013 15.0 0.1 0.031 13.8 0.1 1.5 1 0 0 1 1 1 0 XPG domain containing ABC2_membrane PF01061.24 PSC69376.1 - 1.3e-75 253.4 65.0 1.9e-46 158.2 25.4 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 PSC69376.1 - 5.8e-39 133.8 0.0 6.9e-22 78.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 PSC69376.1 - 6.4e-10 39.3 0.0 0.016 15.0 0.0 3.4 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system PDR_assoc PF08370.11 PSC69376.1 - 1.2e-08 34.5 0.1 1.2e-08 34.5 0.1 3.5 3 0 0 3 3 2 1 Plant PDR ABC transporter associated AAA_16 PF13191.6 PSC69376.1 - 8e-08 32.9 0.3 0.0062 16.9 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 PSC69376.1 - 6.4e-07 29.7 0.5 0.00073 19.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 PSC69376.1 - 7.7e-07 28.9 0.2 0.035 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 PSC69376.1 - 2.2e-06 27.3 0.3 0.0034 17.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 PSC69376.1 - 4.3e-05 24.1 0.0 0.099 13.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain PDR_CDR PF06422.12 PSC69376.1 - 5e-05 23.1 0.2 5e-05 23.1 0.2 3.3 3 0 0 3 3 3 1 CDR ABC transporter AAA_30 PF13604.6 PSC69376.1 - 0.00011 22.0 0.3 0.18 11.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 PSC69376.1 - 0.00014 21.8 0.6 0.0088 16.0 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 PSC69376.1 - 0.00029 21.4 0.0 0.83 10.1 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 PSC69376.1 - 0.00065 20.0 0.1 0.6 10.3 0.1 2.5 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 PSC69376.1 - 0.0017 17.5 13.4 0.0017 17.5 13.4 3.1 3 1 0 3 3 3 1 ABC-2 family transporter protein SMC_N PF02463.19 PSC69376.1 - 0.0023 17.4 0.0 1.3 8.4 0.1 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain ABC_trans_N PF14510.6 PSC69376.1 - 0.0024 18.4 0.0 0.008 16.8 0.0 1.9 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA PF00004.29 PSC69376.1 - 0.0051 17.2 0.1 0.36 11.2 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 PSC69376.1 - 0.0056 16.8 0.1 3.4 7.8 0.1 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 PSC69376.1 - 0.0063 16.6 0.5 1.1 9.4 0.2 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 PSC69376.1 - 0.014 15.0 1.7 0.23 11.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 PSC69376.1 - 0.015 15.3 0.4 2.6 8.0 0.0 2.8 3 0 0 3 3 3 0 NACHT domain AAA_19 PF13245.6 PSC69376.1 - 0.018 15.4 0.1 0.073 13.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.15 PSC69376.1 - 0.037 13.9 0.0 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain NTPase_1 PF03266.15 PSC69376.1 - 0.05 13.5 2.1 3.6 7.5 0.0 3.1 3 0 0 3 3 3 0 NTPase Zeta_toxin PF06414.12 PSC69376.1 - 0.069 12.4 0.2 7.5 5.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 PSC69376.1 - 0.079 13.4 0.0 12 6.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_11 PF13086.6 PSC69376.1 - 0.1 12.4 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 PSC69376.1 - 0.2 11.7 0.2 20 5.2 0.5 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain ABC2_membrane PF01061.24 PSC69377.1 - 1e-75 253.8 64.6 1.9e-46 158.2 25.4 2.7 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 PSC69377.1 - 5.7e-39 133.8 0.0 6.9e-22 78.4 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 PSC69377.1 - 6.3e-10 39.3 0.0 0.016 15.0 0.0 3.4 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system PDR_assoc PF08370.11 PSC69377.1 - 1.2e-08 34.5 0.1 1.2e-08 34.5 0.1 3.5 3 0 0 3 3 2 1 Plant PDR ABC transporter associated AAA_16 PF13191.6 PSC69377.1 - 7.9e-08 32.9 0.3 0.0062 16.9 0.0 2.8 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 PSC69377.1 - 6.3e-07 29.7 0.5 0.00073 19.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 PSC69377.1 - 7.6e-07 28.9 0.2 0.035 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 PSC69377.1 - 2.2e-06 27.3 0.3 0.0034 17.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_18 PF13238.6 PSC69377.1 - 4.3e-05 24.1 0.0 0.098 13.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain PDR_CDR PF06422.12 PSC69377.1 - 5e-05 23.1 0.2 5e-05 23.1 0.2 3.3 3 0 0 3 3 3 1 CDR ABC transporter AAA_30 PF13604.6 PSC69377.1 - 0.00011 22.0 0.3 0.18 11.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 PSC69377.1 - 0.00014 21.8 0.6 0.0088 16.0 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 PSC69377.1 - 0.00029 21.4 0.0 0.83 10.1 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 PSC69377.1 - 0.00064 20.0 0.1 0.6 10.3 0.1 2.5 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 PSC69377.1 - 0.0016 17.6 13.3 0.0016 17.6 13.3 3.1 3 1 0 3 3 3 1 ABC-2 family transporter protein SMC_N PF02463.19 PSC69377.1 - 0.0023 17.4 0.0 1.3 8.4 0.1 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain ABC_trans_N PF14510.6 PSC69377.1 - 0.0024 18.4 0.0 0.0079 16.8 0.0 1.9 2 0 0 2 2 1 1 ABC-transporter N-terminal AAA PF00004.29 PSC69377.1 - 0.0051 17.2 0.1 0.36 11.3 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 PSC69377.1 - 0.0056 16.8 0.1 3.4 7.8 0.1 2.6 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 PSC69377.1 - 0.0063 16.6 0.5 1.1 9.4 0.2 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 PSC69377.1 - 0.014 15.0 1.7 0.22 11.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 PSC69377.1 - 0.015 15.3 0.4 2.6 8.0 0.0 2.8 3 0 0 3 3 3 0 NACHT domain AAA_19 PF13245.6 PSC69377.1 - 0.018 15.4 0.1 0.072 13.4 0.0 2.0 2 0 0 2 2 1 0 AAA domain Rad17 PF03215.15 PSC69377.1 - 0.037 14.0 0.0 11 5.9 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain NTPase_1 PF03266.15 PSC69377.1 - 0.05 13.5 2.1 3.6 7.5 0.0 3.1 3 0 0 3 3 3 0 NTPase Zeta_toxin PF06414.12 PSC69377.1 - 0.069 12.4 0.2 7.5 5.8 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin RNA_helicase PF00910.22 PSC69377.1 - 0.079 13.4 0.0 12 6.4 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_11 PF13086.6 PSC69377.1 - 0.1 12.4 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 PSC69377.1 - 0.2 11.7 0.2 20 5.2 0.5 2.5 2 0 0 2 2 2 0 Helicase HerA, central domain Ribophorin_II PF05817.14 PSC69378.1 - 7.2e-53 180.1 0.0 1e-52 179.6 0.0 1.2 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II FAM176 PF14851.6 PSC69378.1 - 0.031 14.0 0.0 0.055 13.1 0.0 1.3 1 0 0 1 1 1 0 FAM176 family EphA2_TM PF14575.6 PSC69378.1 - 0.04 14.8 0.1 0.087 13.7 0.1 1.6 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 PSC69378.1 - 0.049 13.5 0.7 0.093 12.6 0.7 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Amnionless PF14828.6 PSC69378.1 - 0.068 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Amnionless Miga PF10265.9 PSC69378.1 - 0.069 12.1 0.9 0.1 11.6 0.9 1.1 1 0 0 1 1 1 0 Mitoguardin Protocadherin PF08374.11 PSC69378.1 - 0.084 12.8 0.1 0.084 12.8 0.1 2.0 2 1 0 2 2 2 0 Protocadherin DUF4834 PF16118.5 PSC69378.1 - 0.14 13.2 0.1 0.25 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RVT_2 PF07727.14 PSC69379.1 - 1.1e-73 247.8 0.0 1.5e-73 247.4 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 PSC69379.1 - 2.3e-24 85.6 0.0 4.4e-24 84.7 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 PSC69379.1 - 1.1e-21 77.3 0.0 3.6e-21 75.6 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 PSC69379.1 - 2.9e-09 36.6 0.0 5.4e-09 35.8 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4219 PF13961.6 PSC69379.1 - 4.3e-05 23.1 0.0 8.7e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) rve_3 PF13683.6 PSC69379.1 - 0.0004 20.1 0.0 0.0016 18.2 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain Retrotran_gag_3 PF14244.6 PSC69379.1 - 0.11 12.3 0.0 0.29 11.0 0.0 1.7 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Asp_protease_2 PF13650.6 PSC69379.1 - 0.13 12.9 0.0 1.2 9.8 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease zf-CCHC_3 PF13917.6 PSC69379.1 - 0.14 12.2 0.3 0.38 10.7 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 PSC69379.1 - 0.15 11.8 2.0 0.28 10.9 2.0 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger Crr6 PF08847.11 PSC69379.1 - 0.2 11.3 0.0 0.39 10.4 0.0 1.3 1 0 0 1 1 1 0 Chlororespiratory reduction 6 zf-CCHC_5 PF14787.6 PSC69379.1 - 0.32 10.8 2.5 0.89 9.3 2.5 1.8 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger adh_short PF00106.25 PSC69382.1 - 9.1e-10 38.3 0.1 1.4e-09 37.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC69382.1 - 1.4e-06 28.1 0.6 6.1e-06 26.0 0.6 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 PSC69382.1 - 0.00088 18.8 0.2 0.0021 17.6 0.1 1.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 PSC69382.1 - 0.0021 18.0 0.4 0.003 17.5 0.4 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PSC69382.1 - 0.015 15.2 1.1 0.027 14.4 1.1 1.5 1 0 0 1 1 1 0 NAD(P)H-binding DUF4148 PF13663.6 PSC69382.1 - 0.071 13.3 2.4 0.17 12.1 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) RmlD_sub_bind PF04321.17 PSC69382.1 - 0.1 11.7 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.13 PSC69382.1 - 0.17 11.4 0.1 0.24 10.9 0.1 1.2 1 0 0 1 1 1 0 NmrA-like family 3HCDH_N PF02737.18 PSC69382.1 - 0.21 11.5 0.2 0.27 11.1 0.2 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain bZIP_1 PF00170.21 PSC69383.1 - 6.6e-07 29.3 13.4 1.4e-06 28.3 13.4 1.6 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PSC69383.1 - 6.4e-06 26.2 11.6 6.4e-06 26.2 11.6 2.6 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 PSC69383.1 - 0.038 14.5 9.7 0.12 12.9 9.5 1.9 1 1 0 1 1 1 0 bZIP Maf transcription factor ZapB PF06005.12 PSC69383.1 - 0.044 14.2 1.5 0.086 13.3 1.2 1.6 1 1 0 1 1 1 0 Cell division protein ZapB Mito_fiss_reg PF05308.11 PSC69383.1 - 0.25 11.4 8.5 0.022 14.9 3.5 1.7 2 0 0 2 2 2 0 Mitochondrial fission regulator ACC_epsilon PF13822.6 PSC69384.1 - 0.28 11.9 4.8 0.61 10.8 4.8 1.5 1 0 0 1 1 1 0 Acyl-CoA carboxylase epsilon subunit CBM_20 PF00686.19 PSC69385.1 - 8.6e-12 44.8 0.0 1.6e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Starch binding domain CBM_20 PF00686.19 PSC69386.1 - 8.6e-12 44.8 0.0 1.6e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Starch binding domain CBM_20 PF00686.19 PSC69387.1 - 8.8e-12 44.8 0.0 1.7e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Starch binding domain Methyltransf_31 PF13847.6 PSC69388.1 - 1.2e-18 67.4 0.0 1.9e-18 66.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC69388.1 - 4.4e-13 49.7 0.1 2e-12 47.6 0.2 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC69388.1 - 3.1e-12 47.1 0.0 1e-11 45.4 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC69388.1 - 5.7e-09 36.5 0.1 1.5e-08 35.1 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PSC69388.1 - 9.9e-09 35.0 0.0 1.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 PSC69388.1 - 1.1e-08 35.1 0.0 2.8e-08 33.8 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC69388.1 - 2.6e-06 27.0 0.0 4.6e-06 26.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 PSC69388.1 - 0.00012 21.6 0.0 0.00017 21.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.18 PSC69388.1 - 0.00028 20.3 0.0 0.00081 18.8 0.0 1.7 1 1 0 1 1 1 1 O-methyltransferase domain Methyltransf_18 PF12847.7 PSC69388.1 - 0.0043 17.0 0.0 0.0081 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 PSC69388.1 - 0.0043 16.5 0.0 0.0073 15.8 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase PCMT PF01135.19 PSC69388.1 - 0.038 13.7 0.0 0.064 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Dimerisation2 PF16864.5 PSC69388.1 - 0.063 13.3 0.0 0.21 11.6 0.0 1.9 1 0 0 1 1 1 0 Dimerisation domain F-box PF00646.33 PSC69388.1 - 0.079 12.9 0.0 0.23 11.4 0.0 1.8 2 0 0 2 2 2 0 F-box domain CMAS PF02353.20 PSC69388.1 - 0.17 11.1 0.0 0.28 10.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Proteasome PF00227.26 PSC69389.1 - 1.8e-60 203.7 0.1 4.1e-60 202.5 0.1 1.7 1 0 0 1 1 1 1 Proteasome subunit OB_NTP_bind PF07717.16 PSC69389.1 - 9.3e-20 70.8 0.0 1.8e-19 69.8 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 PSC69389.1 - 4.2e-18 65.6 0.1 4.2e-18 65.6 0.1 4.2 5 0 0 5 5 5 1 Helicase associated domain (HA2) Helicase_C PF00271.31 PSC69389.1 - 1.3e-13 51.3 0.0 4.2e-13 49.6 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PSC69389.1 - 1e-06 28.6 0.0 2.5e-06 27.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PSC69389.1 - 3.8e-05 24.0 0.2 0.00018 21.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PSC69389.1 - 0.00014 22.2 0.1 0.00014 22.2 0.1 2.6 3 0 0 3 3 3 1 AAA domain zf-SNAP50_C PF12251.8 PSC69390.1 - 2.2e-55 187.5 0.0 3.1e-55 187.0 0.0 1.2 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Ferrochelatase PF00762.19 PSC69391.1 - 2.7e-112 375.0 0.0 3.6e-112 374.6 0.0 1.2 1 0 0 1 1 1 1 Ferrochelatase Chloroa_b-bind PF00504.21 PSC69391.1 - 0.00019 22.0 0.0 0.00034 21.2 0.0 1.4 1 0 0 1 1 1 1 Chlorophyll A-B binding protein CbiX PF01903.17 PSC69391.1 - 0.13 12.6 0.0 6.1 7.2 0.0 2.5 2 0 0 2 2 2 0 CbiX Acyltransferase PF01553.21 PSC69392.1 - 7.6e-20 70.9 0.0 1.3e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase DCP2 PF05026.13 PSC69393.1 - 5.9e-26 90.6 0.6 2.5e-25 88.6 0.1 2.0 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.28 PSC69393.1 - 1.5e-14 54.2 0.0 3.5e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 NUDIX domain DUF3306 PF11748.8 PSC69393.1 - 3.4 8.6 6.5 3.2 8.7 4.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3306) ydhR PF08803.11 PSC69395.1 - 2.2e-41 139.7 0.0 2.5e-41 139.5 0.0 1.0 1 0 0 1 1 1 1 Putative mono-oxygenase ydhR WD40 PF00400.32 PSC69396.1 - 1e-11 45.2 1.0 0.0067 17.2 0.0 5.4 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC69396.1 - 3.2e-10 40.2 0.0 0.24 11.7 0.0 5.1 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PSC69396.1 - 3.3e-05 23.0 0.1 0.062 12.3 0.0 3.0 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 PSC69396.1 - 0.091 11.3 0.0 0.18 10.3 0.0 1.5 1 0 0 1 1 1 0 Cytochrome D1 heme domain TFIIE-A_C PF11521.8 PSC69396.1 - 2.4 8.5 5.2 19 5.6 0.7 2.9 3 0 0 3 3 3 0 C-terminal general transcription factor TFIIE alpha TraB PF01963.17 PSC69397.1 - 3.2e-06 27.2 0.0 3.9e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 TraB family WW PF00397.26 PSC69398.1 - 3.9e-05 23.6 0.7 6.2e-05 23.0 0.7 1.4 1 0 0 1 1 1 1 WW domain CAP_N PF01213.19 PSC69398.1 - 0.48 9.9 2.2 0.53 9.7 2.2 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal AAA_2 PF07724.14 PSC69399.1 - 1.3e-41 142.6 0.0 4.2e-41 140.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 PSC69399.1 - 3.1e-14 53.5 0.0 9e-14 52.0 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 PSC69399.1 - 3.6e-09 36.5 0.0 9.8e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein RuvB_N PF05496.12 PSC69399.1 - 4.4e-05 23.3 0.2 0.0011 18.7 0.0 2.6 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PSC69399.1 - 6.1e-05 23.0 0.0 0.00025 21.1 0.1 2.0 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 PSC69399.1 - 0.00025 20.8 0.5 0.0014 18.4 0.0 2.4 3 1 0 3 3 1 1 Sigma-54 interaction domain AAA_22 PF13401.6 PSC69399.1 - 0.00026 21.3 0.2 0.003 17.8 0.2 2.4 1 1 0 1 1 1 1 AAA domain MCM PF00493.23 PSC69399.1 - 0.00041 19.5 0.0 0.00097 18.3 0.0 1.6 1 0 0 1 1 1 1 MCM P-loop domain Mg_chelatase PF01078.21 PSC69399.1 - 0.00044 19.7 0.1 0.0064 15.9 0.0 2.6 3 0 0 3 3 3 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 PSC69399.1 - 0.0013 19.3 0.0 0.003 18.1 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 PSC69399.1 - 0.0024 18.3 0.0 0.013 15.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain IstB_IS21 PF01695.17 PSC69399.1 - 0.0049 16.6 0.0 0.013 15.2 0.0 1.6 2 0 0 2 2 1 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 PSC69399.1 - 0.0068 16.5 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain TsaE PF02367.17 PSC69399.1 - 0.02 14.9 0.1 0.076 13.0 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 PSC69399.1 - 0.022 14.3 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PhoH PF02562.16 PSC69399.1 - 0.024 14.1 0.0 0.13 11.7 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein AAA_18 PF13238.6 PSC69399.1 - 0.028 15.0 0.0 0.078 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PSC69399.1 - 0.042 14.1 0.1 0.28 11.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 PSC69399.1 - 0.043 12.9 0.0 0.13 11.3 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein RNA_helicase PF00910.22 PSC69399.1 - 0.051 14.0 0.0 0.094 13.1 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NACHT PF05729.12 PSC69399.1 - 0.06 13.3 0.0 0.14 12.1 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.6 PSC69399.1 - 0.061 13.3 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 PSC69399.1 - 0.079 12.7 0.2 3.1 7.5 0.0 2.8 2 1 0 3 3 3 0 DEAD/DEAH box helicase SMC_N PF02463.19 PSC69399.1 - 0.11 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 PSC69399.1 - 0.13 12.2 0.3 0.26 11.2 0.0 1.6 2 0 0 2 2 1 0 Rad17 P-loop domain AAA_24 PF13479.6 PSC69399.1 - 0.16 11.6 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 PSC69399.1 - 1.5 9.1 3.8 3.5 8.0 0.1 3.1 3 1 1 4 4 4 0 AAA domain ABC2_membrane PF01061.24 PSC69400.1 - 2e-53 180.9 51.6 2.5e-31 108.7 27.0 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 PSC69400.1 - 5.4e-28 98.2 0.8 3.5e-17 63.2 0.0 2.8 3 0 0 3 3 2 2 ABC transporter DnaJ PF00226.31 PSC69400.1 - 3.3e-12 46.3 0.0 6.3e-12 45.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain AAA_29 PF13555.6 PSC69400.1 - 8.7e-08 31.8 1.0 0.0043 16.8 0.4 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.6 PSC69400.1 - 2.5e-06 27.2 1.5 0.012 15.2 0.0 3.4 3 0 0 3 3 3 2 AAA domain RsgA_GTPase PF03193.16 PSC69400.1 - 3.3e-05 23.8 0.1 0.0054 16.6 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase ABC_trans_N PF14510.6 PSC69400.1 - 0.00017 22.1 0.0 0.00056 20.5 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter N-terminal AAA_22 PF13401.6 PSC69400.1 - 0.00036 20.8 0.5 0.32 11.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PSC69400.1 - 0.00045 20.6 5.2 0.39 11.1 0.0 3.3 3 0 0 3 3 3 2 AAA ATPase domain SMC_N PF02463.19 PSC69400.1 - 0.0015 18.0 0.1 14 5.0 0.0 4.1 5 0 0 5 5 5 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 PSC69400.1 - 0.0036 17.9 0.4 6.4 7.3 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 PSC69400.1 - 0.0068 16.3 0.1 1.1 9.0 0.1 2.4 2 0 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_5 PF07728.14 PSC69400.1 - 0.0075 16.3 1.8 0.079 13.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MMR_HSR1 PF01926.23 PSC69400.1 - 0.0095 16.0 0.2 0.86 9.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 PSC69400.1 - 0.015 15.7 0.0 7.2 7.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 PSC69400.1 - 0.018 15.3 6.1 1.4 9.1 0.0 3.2 3 0 0 3 3 3 0 AAA domain AAA PF00004.29 PSC69400.1 - 0.018 15.5 0.4 0.88 10.0 0.0 3.3 4 0 0 4 4 3 0 ATPase family associated with various cellular activities (AAA) Ploopntkinase3 PF18751.1 PSC69400.1 - 0.023 14.6 4.2 0.46 10.4 0.0 2.7 3 0 0 3 3 2 0 P-loop Nucleotide Kinase3 AAA_33 PF13671.6 PSC69400.1 - 0.062 13.5 5.7 0.6 10.3 0.0 3.8 4 0 0 4 4 4 0 AAA domain NACHT PF05729.12 PSC69400.1 - 0.082 12.8 2.0 4 7.3 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 PSC69400.1 - 0.2 12.1 0.3 1.2 9.6 0.3 2.1 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 PSC69400.1 - 0.23 11.0 0.1 3.8 7.0 0.0 2.6 3 0 0 3 3 3 0 P-loop containing dynein motor region FA_hydroxylase PF04116.13 PSC69401.1 - 1.2e-09 38.6 0.5 1.2e-09 38.6 0.5 1.5 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Symplekin_C PF12295.8 PSC69402.1 - 3.5e-46 157.6 0.0 8.8e-46 156.4 0.0 1.8 1 0 0 1 1 1 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 PSC69402.1 - 4.9e-13 49.3 0.0 9.7e-13 48.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3453) CBM_20 PF00686.19 PSC69402.1 - 6.8e-12 45.1 0.0 1.3e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Starch binding domain Baculo_PEP_C PF04513.12 PSC69402.1 - 2.1 8.4 3.5 0.75 9.8 0.2 1.9 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Type_III_YscX PF09474.10 PSC69402.1 - 3.2 8.1 7.1 0.77 10.1 1.1 3.0 3 0 0 3 3 3 0 Type III secretion system YscX (type_III_YscX) Pyr_redox_2 PF07992.14 PSC69403.1 - 3.6e-43 147.9 0.0 4.3e-43 147.6 0.0 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PSC69403.1 - 4.2e-09 36.8 0.8 3.9e-08 33.8 0.3 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PSC69403.1 - 0.035 13.4 0.1 1.9 7.7 0.1 2.1 1 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PSC69403.1 - 0.075 13.0 0.2 0.4 10.7 0.0 2.3 2 1 1 3 3 3 0 FAD-NAD(P)-binding Ribosomal_L37ae PF01780.19 PSC69403.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal L37ae protein family K_oxygenase PF13434.6 PSC69403.1 - 0.18 10.9 0.0 2.4 7.2 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Calmodulin_bind PF07887.11 PSC69404.1 - 1.6e-12 47.4 0.0 1.4e-11 44.3 0.0 2.1 1 1 0 1 1 1 1 Calmodulin binding protein-like PNISR PF15996.5 PSC69404.1 - 0.65 10.2 19.5 0.87 9.8 9.7 2.3 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR TFIIA PF03153.13 PSC69404.1 - 0.98 9.3 54.3 1 9.3 26.2 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SWI-SNF_Ssr4 PF08549.10 PSC69404.1 - 8.2 4.9 29.1 1.8 7.1 6.1 2.2 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) Neur_chan_memb PF02932.16 PSC69404.1 - 8.7 6.3 7.3 95 2.9 0.0 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Aminotran_4 PF01063.19 PSC69405.1 - 1.3e-35 123.3 0.0 1.6e-35 123.0 0.0 1.0 1 0 0 1 1 1 1 Amino-transferase class IV Lipase_3 PF01764.25 PSC69406.1 - 4.3e-14 52.6 0.0 8e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 PSC69406.1 - 0.0017 18.5 0.7 0.0028 17.8 0.7 1.3 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 PSC69406.1 - 0.0034 16.7 0.7 0.0073 15.6 0.3 1.7 2 0 0 2 2 2 1 Serine aminopeptidase, S33 YjbE PF11106.8 PSC69406.1 - 0.0039 17.4 13.3 0.0039 17.4 13.3 2.8 2 1 0 2 2 2 1 Exopolysaccharide production protein YjbE Abhydrolase_3 PF07859.13 PSC69406.1 - 0.015 15.2 2.1 0.033 14.0 2.1 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 PSC69406.1 - 0.021 14.5 0.0 0.032 14.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 PSC69406.1 - 0.039 13.6 0.0 0.1 12.2 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.8 PSC69406.1 - 0.21 11.1 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Glyco_hydro_38N PF01074.22 PSC69407.1 - 8.5e-86 287.9 0.5 1.2e-85 287.4 0.5 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 PSC69407.1 - 3.5e-31 108.9 0.0 8.7e-31 107.7 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 PSC69407.1 - 1.9e-21 76.0 1.3 2.1e-21 75.9 0.0 1.8 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 PSC69407.1 - 7.5e-09 35.6 0.0 1.5e-08 34.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain UQ_con PF00179.26 PSC69408.1 - 1.3e-47 161.0 0.0 1.5e-47 160.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PSC69408.1 - 0.00027 20.6 0.0 0.00037 20.2 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 PSC69408.1 - 0.00096 19.4 0.0 0.0012 19.1 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 PSC69408.1 - 0.03 14.2 0.0 0.043 13.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain adh_short_C2 PF13561.6 PSC69409.1 - 1.9e-51 174.9 3.7 1e-48 165.9 0.5 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PSC69409.1 - 2.9e-09 36.7 1.2 1.5e-07 31.1 0.1 2.1 2 0 0 2 2 2 2 short chain dehydrogenase Enoyl_reductase PF12241.8 PSC69409.1 - 0.052 12.9 0.6 1.5 8.1 0.0 2.1 1 1 0 2 2 2 0 Trans-2-enoyl-CoA reductase catalytic region DUF4530 PF15039.6 PSC69410.1 - 0.01 16.0 0.4 4 7.6 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4530) SIS_2 PF13580.6 PSC69410.1 - 0.046 13.7 0.2 0.077 13.0 0.2 1.3 1 0 0 1 1 1 0 SIS domain Pkinase PF00069.25 PSC69411.1 - 3.8e-50 170.7 0.0 6e-50 170.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain rve PF00665.26 PSC69411.1 - 1.2e-18 67.4 0.0 2.9e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Pkinase_Tyr PF07714.17 PSC69411.1 - 8.8e-16 58.0 0.0 1.3e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC69411.1 - 0.0004 19.8 0.0 0.001 18.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 PSC69411.1 - 0.00075 19.5 2.6 0.0015 18.5 0.0 2.5 2 1 0 2 2 2 1 Phosphotransferase enzyme family rve_3 PF13683.6 PSC69411.1 - 0.0033 17.2 0.0 0.0091 15.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Pkinase_fungal PF17667.1 PSC69411.1 - 0.063 12.0 0.0 0.18 10.5 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase ATG16 PF08614.11 PSC69412.1 - 0.00094 19.5 22.7 0.00094 19.5 22.7 5.8 1 1 4 5 5 5 2 Autophagy protein 16 (ATG16) Vac_Fusion PF02346.16 PSC69412.1 - 0.032 13.9 0.0 0.14 11.8 0.0 2.2 1 0 0 1 1 1 0 Chordopoxvirus multifunctional envelope protein A27 DUF1541 PF07563.11 PSC69412.1 - 0.22 11.4 0.9 0.69 9.8 0.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1541) Erp_C PF06780.11 PSC69412.1 - 4.1 7.4 6.2 1.9 8.5 1.0 3.0 2 2 1 3 3 3 0 Erp protein C-terminus Abhydrolase_6 PF12697.7 PSC69413.1 - 3.1e-11 44.3 11.5 1e-08 36.0 9.1 2.1 1 1 1 2 2 2 2 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PSC69413.1 - 5.3e-07 29.2 0.5 3e-06 26.7 0.4 2.0 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PSC69413.1 - 1.7e-05 24.6 0.1 0.11 12.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold RcbX PF02341.15 PSC69414.1 - 0.0029 17.8 0.1 1.7 8.9 0.0 2.4 2 0 0 2 2 2 2 RbcX protein 2-oxoacid_dh PF00198.23 PSC69415.1 - 7.5e-74 248.1 0.0 1.1e-73 247.6 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 PSC69415.1 - 1.4e-14 53.7 0.2 1.5e-13 50.4 0.0 2.5 3 0 0 3 3 3 1 Biotin-requiring enzyme E3_binding PF02817.17 PSC69415.1 - 1.2e-08 35.2 0.3 4e-08 33.5 0.3 2.0 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 PSC69415.1 - 2.8e-05 23.8 0.0 0.00069 19.4 0.0 2.9 3 0 0 3 3 3 1 Biotin-lipoyl like Croc_4 PF17691.1 PSC69415.1 - 0.6 10.1 3.9 0.6 10.1 1.0 2.5 3 0 0 3 3 3 0 Contingent replication of cDNA 4 ANAPC1 PF12859.7 PSC69416.1 - 1.8e-07 31.7 0.0 3.1e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 APC1_C PF18122.1 PSC69417.1 - 1.6e-25 90.0 0.0 3.8e-25 88.8 0.0 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex sub unit 1 C-terminal domain ANAPC1 PF12859.7 PSC69417.1 - 2.2e-06 28.3 0.0 5.1e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 PSC69417.1 - 0.062 13.8 23.5 0.82 10.2 0.2 6.2 6 0 0 6 6 6 0 Proteasome/cyclosome repeat APC1_C PF18122.1 PSC69418.1 - 1.3e-25 90.3 0.0 3.2e-25 89.0 0.0 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex sub unit 1 C-terminal domain PC_rep PF01851.22 PSC69418.1 - 0.014 15.8 22.6 0.72 10.4 0.2 6.3 6 0 0 6 6 6 0 Proteasome/cyclosome repeat APC1_C PF18122.1 PSC69419.1 - 1.2e-25 90.3 0.0 3.2e-25 89.0 0.0 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex sub unit 1 C-terminal domain PC_rep PF01851.22 PSC69419.1 - 0.032 14.7 23.5 0.72 10.4 0.2 6.3 6 0 0 6 6 6 0 Proteasome/cyclosome repeat APC1_C PF18122.1 PSC69420.1 - 1.3e-25 90.3 0.0 3.2e-25 89.0 0.0 1.7 2 0 0 2 2 2 1 Anaphase-promoting complex sub unit 1 C-terminal domain PC_rep PF01851.22 PSC69420.1 - 0.014 15.8 22.6 0.72 10.4 0.2 6.3 6 0 0 6 6 6 0 Proteasome/cyclosome repeat Fer4_14 PF13394.6 PSC69421.1 - 0.083 13.0 0.1 0.084 13.0 0.1 1.1 1 0 0 1 1 1 0 4Fe-4S single cluster domain La PF05383.17 PSC69422.1 - 2.3e-19 69.2 0.0 4.5e-19 68.3 0.0 1.5 1 0 0 1 1 1 1 La domain RRM_3 PF08777.11 PSC69422.1 - 1.4e-14 54.0 0.0 1.3e-13 50.9 0.0 2.3 2 0 0 2 2 2 1 RNA binding motif RRM_1 PF00076.22 PSC69422.1 - 4.7e-08 32.7 0.2 6.1e-06 26.0 0.0 2.8 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Histone PF00125.24 PSC69424.1 - 5.1e-14 52.8 1.0 2.6e-13 50.5 0.0 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC69424.1 - 5.6e-05 23.3 0.0 9.8e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone RP-C PF03428.13 PSC69424.1 - 0.047 13.3 0.1 3.3 7.3 0.0 2.0 1 1 1 2 2 2 0 Replication protein C N-terminal domain TFIID_20kDa PF03847.13 PSC69424.1 - 0.12 12.9 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A ArfGap PF01412.18 PSC69425.1 - 0.00065 19.7 0.0 0.00092 19.3 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PASTA PF03793.19 PSC69426.1 - 0.034 14.0 0.1 0.057 13.3 0.1 1.3 1 0 0 1 1 1 0 PASTA domain SUIM_assoc PF16619.5 PSC69426.1 - 1.9 8.6 10.6 0.19 11.8 4.6 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PNISR PF15996.5 PSC69427.1 - 1.6e-08 35.1 20.4 3e-07 30.9 2.6 5.0 3 1 2 5 5 5 2 Arginine/serine-rich protein PNISR VCBS PF13517.6 PSC69429.1 - 1.3e-23 83.4 14.4 1.4e-06 28.7 0.6 7.3 5 2 1 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 PSC69429.1 - 2.8e-09 36.9 38.7 0.028 14.6 0.1 8.6 7 0 0 7 7 6 6 FG-GAP repeat Cytochrom_B561 PF03188.16 PSC69429.1 - 2.1e-06 27.9 5.7 3.9e-06 27.1 5.7 1.4 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 PQQ PF01011.21 PSC69429.1 - 5.6e-06 26.0 0.1 0.4 10.7 0.0 5.0 5 0 0 5 5 5 1 PQQ enzyme repeat BBS2_Mid PF14783.6 PSC69429.1 - 0.00052 20.0 0.3 0.93 9.6 0.0 4.3 4 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region Itfg2 PF15907.5 PSC69429.1 - 0.0016 17.6 3.9 3.5 6.6 0.3 4.9 4 1 0 4 4 4 1 Integrin-alpha FG-GAP repeat-containing protein 2 TcdB_toxin_midN PF12256.8 PSC69429.1 - 0.018 14.4 5.3 46 3.3 0.0 5.1 3 1 2 5 5 5 0 Insecticide toxin TcdB middle/N-terminal region DUF2722 PF10846.8 PSC69429.1 - 0.022 13.8 3.8 0.031 13.2 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4079 PF13301.6 PSC69429.1 - 0.4 10.8 4.1 19 5.4 3.7 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) TFIIA PF03153.13 PSC69429.1 - 0.66 9.9 12.1 1.4 8.8 12.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4175 PF13779.6 PSC69429.1 - 7.9 4.2 19.8 17 3.1 19.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Acetyltransf_1 PF00583.25 PSC69431.1 - 2.1e-09 37.6 0.2 2.8e-09 37.2 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PSC69431.1 - 2.9e-09 37.2 0.2 4.2e-09 36.7 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PSC69431.1 - 2.1e-07 30.9 0.0 3.5e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PSC69431.1 - 0.00045 20.3 0.0 0.00083 19.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC69431.1 - 0.045 13.7 0.0 0.072 13.1 0.0 1.4 1 0 0 1 1 1 0 FR47-like protein Ly49 PF08391.10 PSC69432.1 - 0.035 14.5 0.0 0.054 13.9 0.0 1.2 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region stn_TNFRSF12A PF12191.8 PSC69432.1 - 0.038 14.2 1.1 0.038 14.2 1.1 2.2 2 1 1 3 3 3 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Prominin PF05478.11 PSC69432.1 - 0.33 8.9 0.1 0.43 8.5 0.1 1.1 1 0 0 1 1 1 0 Prominin DUF4381 PF14316.6 PSC69432.1 - 0.47 10.7 6.0 0.061 13.6 1.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Malic_M PF03949.15 PSC69433.1 - 1.1e-89 300.1 0.3 1.5e-89 299.7 0.3 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 PSC69433.1 - 5.4e-66 221.8 0.0 8e-66 221.3 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain PRiA4_ORF3 PF07929.11 PSC69434.1 - 3.1e-06 27.0 0.1 0.00054 19.7 0.0 2.1 2 0 0 2 2 2 2 Plasmid pRiA4b ORF-3-like protein ACBP PF00887.19 PSC69435.1 - 2.8e-30 104.3 1.8 4.5e-30 103.7 1.8 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Histone PF00125.24 PSC69436.1 - 2.5e-15 57.0 0.0 2.9e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC69436.1 - 4.7e-07 30.0 0.0 7e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PAN_4 PF14295.6 PSC69437.1 - 0.0092 15.9 5.6 0.66 9.9 2.5 2.5 2 0 0 2 2 2 2 PAN domain Yip1 PF04893.17 PSC69437.1 - 0.095 12.4 0.0 0.15 11.8 0.0 1.2 1 0 0 1 1 1 0 Yip1 domain DUF667 PF05018.13 PSC69438.1 - 1.5e-87 292.1 0.0 1.7e-87 291.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF667) CHCH PF06747.13 PSC69439.1 - 0.24 11.6 2.8 0.35 11.0 2.8 1.3 1 0 0 1 1 1 0 CHCH domain RTC PF01137.21 PSC69440.1 - 3.3e-55 186.7 0.0 4.3e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 PSC69440.1 - 2.9e-36 124.1 0.5 6.4e-36 123.0 0.5 1.6 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain NUDIX PF00293.28 PSC69440.1 - 7.6e-16 58.3 0.1 1.6e-15 57.3 0.1 1.5 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 PSC69440.1 - 5.2e-07 29.6 0.0 9.8e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Acyl-ACP_TE PF01643.17 PSC69441.1 - 3.6e-46 157.5 0.0 5e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Acyl-ACP thioesterase DUF1825 PF08855.10 PSC69441.1 - 7.5e-18 64.3 4.6 1.5e-17 63.3 4.6 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1825) 4HBT_2 PF13279.6 PSC69441.1 - 0.00068 20.1 0.1 0.032 14.7 0.1 2.5 2 0 0 2 2 2 1 Thioesterase-like superfamily STI1 PF17830.1 PSC69441.1 - 0.004 17.0 0.2 0.035 14.0 0.3 2.5 3 0 0 3 3 3 1 STI1 domain PrmA PF06325.13 PSC69443.1 - 8.8e-14 51.6 3.3 1.6e-10 40.9 1.2 2.3 2 0 0 2 2 2 2 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PSC69443.1 - 7e-10 39.5 5.0 1.7e-08 35.0 0.2 4.5 5 1 1 6 6 4 1 Methyltransferase domain MTS PF05175.14 PSC69443.1 - 8.2e-08 32.0 1.7 4.2e-06 26.4 0.5 2.5 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 PSC69443.1 - 4.3e-06 26.6 0.5 7.7e-05 22.5 0.1 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC69443.1 - 1.7e-05 25.4 0.4 0.0002 22.0 0.1 2.9 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC69443.1 - 1.9e-05 24.6 1.9 0.00011 22.1 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.7 PSC69443.1 - 0.00013 22.0 0.1 0.00025 21.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 PSC69443.1 - 0.00026 21.0 2.0 0.0055 16.7 0.1 3.3 4 0 0 4 4 3 1 Methyltransferase domain Cons_hypoth95 PF03602.15 PSC69443.1 - 0.00061 19.5 0.7 0.026 14.2 0.2 2.4 2 0 0 2 2 2 1 Conserved hypothetical protein 95 TPR_2 PF07719.17 PSC69443.1 - 0.00071 19.5 3.9 0.2 11.9 0.1 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat PRMT5_C PF17286.2 PSC69443.1 - 0.0009 19.2 0.0 0.0061 16.4 0.0 2.0 2 0 0 2 2 2 1 PRMT5 oligomerisation domain PCMT PF01135.19 PSC69443.1 - 0.0009 19.0 0.1 0.018 14.8 0.0 2.2 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 PSC69443.1 - 0.0017 19.1 0.2 0.017 15.8 0.0 2.9 3 0 0 3 3 1 1 Methyltransferase domain RrnaAD PF00398.20 PSC69443.1 - 0.0034 16.5 0.0 0.022 13.8 0.0 1.9 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase CMAS PF02353.20 PSC69443.1 - 0.0065 15.8 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_16 PF10294.9 PSC69443.1 - 0.014 15.1 0.0 0.86 9.3 0.0 2.2 2 0 0 2 2 2 0 Lysine methyltransferase TPR_1 PF00515.28 PSC69443.1 - 0.046 13.6 3.1 9.4 6.2 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Ubie_methyltran PF01209.18 PSC69443.1 - 0.047 13.0 0.0 0.087 12.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family GCD14 PF08704.10 PSC69443.1 - 0.055 13.1 0.1 0.16 11.7 0.0 1.6 1 1 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit DUF3856 PF12968.7 PSC69443.1 - 0.094 12.8 0.9 0.31 11.1 0.9 1.9 1 0 0 1 1 1 0 Domain of Unknown Function (DUF3856) TehB PF03848.14 PSC69443.1 - 0.15 11.5 0.0 4.7 6.6 0.0 2.3 2 0 0 2 2 2 0 Tellurite resistance protein TehB DUF3298 PF11738.8 PSC69443.1 - 0.18 12.9 0.3 0.44 11.6 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3298) TPR_8 PF13181.6 PSC69443.1 - 3.2 8.2 4.8 3.5 8.1 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat PGA_cap PF09587.10 PSC69444.1 - 7.2e-54 182.9 0.1 8.4e-54 182.7 0.1 1.0 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap PAC2 PF09754.9 PSC69444.1 - 0.083 12.9 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 PAC2 family PGA_cap PF09587.10 PSC69445.1 - 1.4e-63 214.8 0.0 1.7e-63 214.5 0.0 1.1 1 0 0 1 1 1 1 Bacterial capsule synthesis protein PGA_cap EB1 PF03271.17 PSC69446.1 - 6.3e-16 58.3 0.7 6.3e-16 58.3 0.7 1.9 2 0 0 2 2 2 1 EB1-like C-terminal motif CH PF00307.31 PSC69446.1 - 3.6e-08 33.5 0.0 2.4e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PSC69446.1 - 0.0061 16.4 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 CAMSAP CH domain TolA_bind_tri PF16331.5 PSC69446.1 - 0.0072 16.4 1.1 0.012 15.7 0.3 1.7 2 0 0 2 2 2 1 TolA binding protein trimerisation Umbravirus_LDM PF04817.12 PSC69446.1 - 0.048 13.0 1.0 0.072 12.4 1.0 1.2 1 0 0 1 1 1 0 Umbravirus long distance movement (LDM) family Cnn_1N PF07989.11 PSC69446.1 - 0.26 11.4 4.4 0.11 12.7 1.5 1.9 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 PALP PF00291.25 PSC69447.1 - 9e-65 219.0 1.6 9.9e-65 218.8 1.6 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 PSC69447.1 - 0.074 13.0 0.3 0.46 10.5 0.3 2.2 1 1 0 1 1 1 0 Zinc-binding dehydrogenase DUF5633 PF18656.1 PSC69448.1 - 2 8.4 4.6 0.64 10.0 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5633) Mlo PF03094.15 PSC69449.1 - 3.7e-55 187.2 0.0 2.7e-42 144.8 0.0 2.9 2 1 0 2 2 2 2 Mlo family Pkinase_Tyr PF07714.17 PSC69449.1 - 7.6e-53 179.4 0.0 2e-52 178.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Ribosomal_L18A PF01775.17 PSC69449.1 - 1.4e-52 176.9 0.7 2.2e-52 176.2 0.7 1.3 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Pkinase PF00069.25 PSC69449.1 - 4.9e-50 170.4 0.0 9.5e-50 169.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PSC69449.1 - 7.9e-12 45.2 8.1 0.04 14.3 0.0 5.0 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 PSC69449.1 - 5.2e-06 26.7 0.7 2.4e-05 24.5 0.7 2.3 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 PSC69449.1 - 0.00018 21.2 10.2 0.026 14.3 0.1 4.5 3 2 2 5 5 5 2 Leucine rich repeat LRR_1 PF00560.33 PSC69449.1 - 0.32 11.7 2.4 1.9e+02 3.3 0.0 5.3 7 0 0 7 7 7 0 Leucine Rich Repeat Beta-APP PF03494.13 PSC69449.1 - 0.4 10.6 5.6 1.4 8.8 5.6 1.9 1 0 0 1 1 1 0 Beta-amyloid peptide (beta-APP) Ion_trans_2 PF07885.16 PSC69450.1 - 7.2e-10 38.7 9.1 7.2e-10 38.7 9.1 2.7 2 1 0 2 2 2 1 Ion channel Ion_trans PF00520.31 PSC69450.1 - 7.9e-09 35.1 14.7 1.2e-08 34.5 14.7 1.2 1 0 0 1 1 1 1 Ion transport protein cNMP_binding PF00027.29 PSC69450.1 - 0.0023 18.0 0.0 2.9 8.0 0.0 3.4 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain IRK PF01007.20 PSC69450.1 - 0.11 12.3 2.6 0.26 11.1 2.6 1.6 1 0 0 1 1 1 0 Inward rectifier potassium channel transmembrane domain PP2C PF00481.21 PSC69451.1 - 1.9e-41 142.4 0.0 3.2e-41 141.7 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C SBP PF03110.14 PSC69451.1 - 7.8e-28 96.6 9.0 1.6e-27 95.6 9.0 1.6 1 0 0 1 1 1 1 SBP domain Ank_3 PF13606.6 PSC69451.1 - 0.043 14.4 0.1 3.8 8.4 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeat Spt20 PF12090.8 PSC69451.1 - 7.2 6.2 8.8 12 5.5 8.8 1.2 1 0 0 1 1 1 0 Spt20 family SAM_decarbox PF01536.16 PSC69452.1 - 4.5e-98 328.5 0.0 5.9e-98 328.2 0.0 1.1 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Orn_Arg_deC_N PF02784.16 PSC69452.1 - 9.4e-68 228.2 0.0 1.3e-67 227.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 PSC69452.1 - 1.1e-11 44.8 0.0 7.1e-11 42.2 0.0 2.2 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Dynein_attach_N PF15867.5 PSC69453.1 - 7.3e-09 35.5 0.0 1.2e-08 34.7 0.0 1.3 1 0 0 1 1 1 1 Dynein attachment factor N-terminus TraG_N PF07916.11 PSC69453.1 - 0.016 14.1 2.9 0.019 13.9 2.9 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Roughex PF06020.11 PSC69453.1 - 0.81 8.7 3.4 1.2 8.2 3.4 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Mito_carr PF00153.27 PSC69456.1 - 2.8e-55 184.2 1.7 9.3e-22 76.8 0.1 3.2 2 1 1 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 PSC69456.1 - 0.0015 17.8 0.6 0.56 9.3 0.0 3.2 3 0 0 3 3 3 2 Gammaproteobacterial serine protease Nop14 PF04147.12 PSC69457.1 - 4.9e-186 620.6 19.8 6.3e-81 272.9 28.2 3.1 2 1 1 3 3 3 3 Nop14-like family Nop14 PF04147.12 PSC69458.1 - 4.9e-186 620.6 19.8 6.3e-81 272.9 28.2 3.1 2 1 1 3 3 3 3 Nop14-like family Chloroa_b-bind PF00504.21 PSC69459.1 - 3.8e-08 34.0 5.1 9.8e-06 26.2 5.1 2.1 1 1 0 1 1 1 1 Chlorophyll A-B binding protein FAF PF11250.8 PSC69459.1 - 0.047 13.9 0.0 1.5 9.1 0.0 2.2 2 0 0 2 2 2 0 Fantastic Four meristem regulator Form_Nir_trans PF01226.17 PSC69461.1 - 4.4e-59 199.7 29.2 5.2e-59 199.4 29.2 1.0 1 0 0 1 1 1 1 Formate/nitrite transporter zf-CCCH PF00642.24 PSC69462.1 - 3e-12 46.1 13.6 4.4e-07 29.6 3.0 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 PSC69462.1 - 9.6e-07 28.5 0.1 3.5e-06 26.7 0.1 2.0 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 PSC69462.1 - 3.9e-05 23.5 14.2 0.011 15.7 2.3 2.5 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 PSC69462.1 - 0.00022 21.9 7.5 0.16 12.7 0.1 3.3 3 0 0 3 3 3 2 Torus domain Nup35_RRM_2 PF14605.6 PSC69462.1 - 0.027 14.5 0.2 0.069 13.2 0.2 1.7 1 1 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCCH_4 PF18044.1 PSC69462.1 - 0.11 12.4 12.5 0.45 10.4 3.5 2.4 2 0 0 2 2 2 0 CCCH-type zinc finger Form_Nir_trans PF01226.17 PSC69463.1 - 2.5e-51 174.3 29.8 3.7e-51 173.7 29.8 1.3 1 0 0 1 1 1 1 Formate/nitrite transporter Form_Nir_trans PF01226.17 PSC69464.1 - 3.3e-58 196.8 29.2 4.4e-58 196.4 29.2 1.2 1 0 0 1 1 1 1 Formate/nitrite transporter zf-CCCH PF00642.24 PSC69464.1 - 1.2e-11 44.2 13.6 9.3e-07 28.6 3.0 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.22 PSC69464.1 - 2.9e-06 27.0 0.1 8.3e-06 25.5 0.1 1.8 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 PSC69464.1 - 0.00014 21.8 14.2 0.023 14.7 2.3 2.6 2 0 0 2 2 2 2 Zinc finger domain Torus PF16131.5 PSC69464.1 - 0.0012 19.5 6.8 0.35 11.6 0.1 3.1 3 0 0 3 3 3 2 Torus domain Nup35_RRM_2 PF14605.6 PSC69464.1 - 0.068 13.2 0.2 0.15 12.1 0.2 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif zf-CCCH_4 PF18044.1 PSC69464.1 - 0.35 10.7 12.5 0.92 9.4 3.5 2.7 2 0 0 2 2 2 0 CCCH-type zinc finger LRR_4 PF12799.7 PSC69465.1 - 0.00015 22.1 6.7 1.2 9.6 0.0 5.6 3 2 3 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PSC69465.1 - 0.014 15.8 3.8 21 6.2 0.0 5.1 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_8 PF13855.6 PSC69465.1 - 0.26 11.1 13.3 0.26 11.1 0.6 5.0 5 1 1 6 6 6 0 Leucine rich repeat mRNA_cap_enzyme PF01331.19 PSC69466.1 - 2.4e-13 50.3 0.0 1.3e-05 25.1 0.0 3.2 3 0 0 3 3 3 3 mRNA capping enzyme, catalytic domain Rubis-subs-bind PF09273.11 PSC69466.1 - 7.7e-08 33.1 0.0 3e-07 31.2 0.0 2.0 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding AAA_18 PF13238.6 PSC69466.1 - 9.1e-06 26.2 0.0 2.1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain SET PF00856.28 PSC69466.1 - 0.00042 20.8 0.0 0.0032 17.9 0.0 2.5 2 0 0 2 2 2 1 SET domain AAA_17 PF13207.6 PSC69466.1 - 0.0006 20.3 0.0 0.0019 18.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PSC69466.1 - 0.0015 18.8 0.0 0.008 16.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain F-box-like PF12937.7 PSC69466.1 - 0.002 18.0 0.2 0.0057 16.5 0.0 1.9 2 0 0 2 2 1 1 F-box-like AAA_16 PF13191.6 PSC69466.1 - 0.0034 17.8 1.0 0.0034 17.8 1.0 3.7 5 1 0 5 5 5 1 AAA ATPase domain AAA PF00004.29 PSC69466.1 - 0.0069 16.8 0.0 0.015 15.8 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 PSC69466.1 - 0.0071 16.5 1.1 0.09 12.9 0.1 3.2 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.14 PSC69466.1 - 0.019 15.0 0.0 0.085 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 PSC69466.1 - 0.035 14.3 0.7 0.2 11.9 0.7 2.3 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.6 PSC69466.1 - 0.064 13.5 2.1 0.12 12.7 0.0 2.6 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 PSC69466.1 - 0.13 11.9 0.0 0.34 10.6 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Methyltransf_11 PF08241.12 PSC69467.1 - 5.7e-19 68.6 0.0 1.2e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC69467.1 - 1.1e-18 67.7 0.0 2.4e-18 66.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC69467.1 - 7.1e-12 45.9 0.0 1.4e-11 45.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC69467.1 - 1.3e-11 44.3 0.0 2.1e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 PSC69467.1 - 2e-10 40.6 0.0 3.9e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC69467.1 - 3.3e-09 36.8 0.0 6e-09 35.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 PSC69467.1 - 1.9e-05 24.1 0.0 3.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_24 PF13578.6 PSC69467.1 - 0.00022 22.2 0.0 0.00046 21.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PSC69467.1 - 0.001 18.7 0.0 0.004 16.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 PSC69467.1 - 0.033 14.0 0.0 0.051 13.4 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase PAP_fibrillin PF04755.12 PSC69468.1 - 5e-27 95.2 0.0 1e-26 94.1 0.0 1.5 1 0 0 1 1 1 1 PAP_fibrillin TraG_N PF07916.11 PSC69468.1 - 9.8 4.9 11.7 15 4.3 11.7 1.3 1 0 0 1 1 1 0 TraG-like protein, N-terminal region TOC159_MAD PF11886.8 PSC69469.1 - 1e-72 244.3 0.0 1.6e-72 243.6 0.0 1.3 1 0 0 1 1 1 1 Translocase of chloroplast 159/132, membrane anchor domain AIG1 PF04548.16 PSC69469.1 - 5.5e-14 52.0 0.0 8.6e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 PSC69469.1 - 3.4e-05 23.9 0.0 5.8e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 PSC69469.1 - 0.028 14.8 0.0 0.053 14.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PSC69469.1 - 0.13 12.6 2.1 0.94 9.8 0.7 2.7 2 1 0 2 2 2 0 AAA ATPase domain Galactosyl_T PF01762.21 PSC69470.1 - 2.3e-16 60.2 0.0 1.1e-12 48.2 0.0 2.4 2 1 0 2 2 2 2 Galactosyltransferase Serglycin PF04360.12 PSC69470.1 - 0.18 11.7 0.5 1.1 9.2 0.0 2.2 2 0 0 2 2 2 0 Serglycin DUF5308 PF17233.2 PSC69470.1 - 0.4 10.9 9.6 0.13 12.5 5.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5308) DUF5529 PF17669.1 PSC69470.1 - 0.96 9.5 0.0 0.96 9.5 0.0 3.5 4 0 0 4 4 4 0 Family of unknown function (DUF5529) Galactosyl_T PF01762.21 PSC69471.1 - 9.3e-15 55.0 0.0 4.4e-11 43.0 0.0 2.4 2 1 0 2 2 2 2 Galactosyltransferase Serglycin PF04360.12 PSC69471.1 - 0.19 11.7 0.5 1.1 9.1 0.0 2.2 2 0 0 2 2 2 0 Serglycin DUF5308 PF17233.2 PSC69471.1 - 0.43 10.8 9.6 0.14 12.4 5.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5308) RSN1_7TM PF02714.15 PSC69472.1 - 1.5e-42 145.8 10.6 3.2e-42 144.8 10.6 1.5 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 PSC69472.1 - 2.6e-31 108.5 0.9 2.6e-31 108.5 0.9 2.9 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 PSC69472.1 - 9e-05 22.8 0.0 0.0002 21.7 0.0 1.7 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter ketoacyl-synt PF00109.26 PSC69473.1 - 2.3e-143 476.2 33.4 1.2e-53 182.3 1.2 5.7 5 0 0 5 5 4 3 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 PSC69473.1 - 5.1e-96 319.8 49.0 8.7e-38 130.0 9.7 6.3 6 0 0 6 6 6 3 KR domain AMP-binding PF00501.28 PSC69473.1 - 4.6e-89 298.9 0.5 3.9e-88 295.9 0.0 2.7 2 0 0 2 2 2 1 AMP-binding enzyme Ketoacyl-synt_C PF02801.22 PSC69473.1 - 1e-84 280.4 14.0 1.7e-29 102.2 2.7 4.9 3 0 0 3 3 3 3 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 PSC69473.1 - 4.5e-64 212.7 13.4 2.1e-12 47.2 0.0 7.0 6 0 0 6 6 6 6 Phosphopantetheine attachment site PS-DH PF14765.6 PSC69473.1 - 2e-35 122.5 28.8 4.6e-13 49.1 4.3 5.9 3 2 0 3 3 3 3 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.6 PSC69473.1 - 3.3e-27 96.1 2.6 2.1e-13 51.5 0.2 3.5 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 PSC69473.1 - 3.5e-23 82.0 9.3 8.2e-13 48.5 1.0 3.3 2 0 0 2 2 2 2 Zinc-binding dehydrogenase AMP-binding_C PF13193.6 PSC69473.1 - 2.9e-18 66.6 0.1 1.9e-17 64.0 0.1 2.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain KAsynt_C_assoc PF16197.5 PSC69473.1 - 2.6e-08 34.3 0.1 0.24 11.9 0.0 3.6 3 0 0 3 3 3 3 Ketoacyl-synthetase C-terminal extension ADH_N PF08240.12 PSC69473.1 - 8.7e-07 28.8 2.0 0.013 15.4 0.4 2.7 2 0 0 2 2 2 2 Alcohol dehydrogenase GroES-like domain adh_short PF00106.25 PSC69473.1 - 0.00017 21.1 3.6 0.00017 21.1 3.6 5.9 6 0 0 6 6 6 2 short chain dehydrogenase DEK_C PF08766.11 PSC69473.1 - 0.035 14.0 0.0 28 4.7 0.0 3.3 3 0 0 3 3 3 0 DEK C terminal domain NUFIP1 PF10453.9 PSC69474.1 - 9e-07 28.7 1.1 9e-07 28.7 1.1 2.1 2 0 0 2 2 2 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) DNA_pol_phi PF04931.13 PSC69474.1 - 1.3 7.0 6.1 2 6.4 6.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi EF-hand_8 PF13833.6 PSC69475.1 - 1.6e-06 27.8 0.0 3.3e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 PSC69475.1 - 1.1e-05 25.7 1.3 2.3e-05 24.7 0.2 2.1 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 PSC69475.1 - 0.0019 17.6 0.1 0.0096 15.4 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 PSC69475.1 - 0.023 14.6 0.0 0.15 12.1 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain Apolipoprotein PF01442.18 PSC69475.1 - 0.029 14.2 2.0 2.7 7.8 0.0 2.7 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain EF-hand_5 PF13202.6 PSC69475.1 - 0.043 13.3 0.0 0.12 11.9 0.0 1.8 1 0 0 1 1 1 0 EF hand AIP3 PF03915.13 PSC69475.1 - 2.9 6.9 5.7 0.72 8.9 0.5 2.2 2 1 0 2 2 2 0 Actin interacting protein 3 ESSS PF10183.9 PSC69476.1 - 0.0069 16.6 0.0 0.0069 16.6 0.0 1.1 1 0 0 1 1 1 1 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) 5_3_exonuc_N PF02739.16 PSC69477.1 - 6.5e-07 29.4 0.0 1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 PSC69477.1 - 1.3e-05 25.7 0.0 2.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_2 PF12826.7 PSC69477.1 - 0.095 12.8 0.1 0.23 11.6 0.1 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif NAD_binding_10 PF13460.6 PSC69478.1 - 1.2e-13 51.4 0.3 2.1e-13 50.5 0.3 1.4 1 1 0 1 1 1 1 NAD(P)H-binding CnrY PF17524.2 PSC69478.1 - 9.7 6.5 7.7 1.1 9.5 2.1 2.2 2 1 0 2 2 2 0 Anti-sigma factor CnrY Sec1 PF00995.23 PSC69479.1 - 3e-114 383.3 0.0 3.4e-114 383.2 0.0 1.0 1 0 0 1 1 1 1 Sec1 family LRR_6 PF13516.6 PSC69480.1 - 3.6e-16 57.8 12.9 1.3 9.3 0.0 12.1 12 0 0 12 12 12 5 Leucine Rich repeat LRR_8 PF13855.6 PSC69480.1 - 3.3e-09 36.4 10.6 0.0023 17.7 0.1 6.6 7 0 0 7 7 7 3 Leucine rich repeat LRR_4 PF12799.7 PSC69480.1 - 3.7e-09 36.7 8.1 0.18 12.3 0.0 7.2 6 2 1 8 8 8 3 Leucine Rich repeats (2 copies) MFS_1 PF07690.16 PSC69480.1 - 3.5e-08 32.7 37.8 0.00013 21.0 29.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TIG_plexin PF17960.1 PSC69480.1 - 0.025 14.6 0.1 0.05 13.6 0.1 1.4 1 0 0 1 1 1 0 TIG domain LRR_1 PF00560.33 PSC69480.1 - 0.029 14.9 12.6 31 5.6 0.0 8.0 8 1 1 9 9 9 0 Leucine Rich Repeat RB_A PF01858.17 PSC69481.1 - 7.8e-46 156.4 0.0 2.7e-44 151.4 0.0 2.6 3 0 0 3 3 3 1 Retinoblastoma-associated protein A domain RB_B PF01857.20 PSC69481.1 - 1.2e-34 119.1 0.0 1.2e-34 119.1 0.0 1.7 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain DUF3452 PF11934.8 PSC69481.1 - 1.3e-08 34.5 0.1 3.3e-08 33.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF3452) TFIIA PF03153.13 PSC69481.1 - 1.5 8.7 24.3 0.021 14.8 5.8 3.0 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit DUF563 PF04577.14 PSC69482.1 - 1.7e-10 41.4 0.0 3.5e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) PCI PF01399.27 PSC69483.1 - 2.6e-15 56.8 0.2 3.5e-14 53.2 0.0 2.7 3 0 0 3 3 3 1 PCI domain CSN4_RPN5_eIF3a PF18420.1 PSC69483.1 - 0.013 15.7 0.2 0.028 14.6 0.2 1.6 1 0 0 1 1 1 0 CSN4/RPN5/eIF3a helix turn helix domain TPR_8 PF13181.6 PSC69483.1 - 0.034 14.4 1.3 15 6.1 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat Virulence_fact PF13769.6 PSC69483.1 - 4.4 7.6 6.0 1.8 8.8 0.5 3.0 3 0 0 3 3 3 0 Virulence factor Coprogen_oxidas PF01218.18 PSC69484.1 - 0.15 10.7 0.3 0.16 10.7 0.3 1.0 1 0 0 1 1 1 0 Coproporphyrinogen III oxidase NAD_binding_7 PF13241.6 PSC69484.1 - 0.29 11.6 3.1 4.8 7.7 0.2 2.1 1 1 1 2 2 2 0 Putative NAD(P)-binding WLM PF08325.10 PSC69486.1 - 7.8e-18 65.2 0.0 1.5e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 WLM domain DUF45 PF01863.17 PSC69486.1 - 0.0023 18.0 1.6 0.026 14.6 0.7 2.2 2 0 0 2 2 2 1 Protein of unknown function DUF45 SprT-like PF10263.9 PSC69486.1 - 0.016 15.1 0.0 0.032 14.1 0.0 1.5 1 0 0 1 1 1 0 SprT-like family Zincin_1 PF06262.11 PSC69486.1 - 0.11 12.5 0.1 0.34 11.0 0.1 1.7 1 0 0 1 1 1 0 Zincin-like metallopeptidase TFIIA PF03153.13 PSC69486.1 - 0.98 9.3 6.9 1 9.3 6.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HAD_2 PF13419.6 PSC69487.1 - 3.7e-17 63.0 0.0 2.6e-16 60.2 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PSC69487.1 - 2.1e-10 41.2 0.3 2.1e-10 41.2 0.3 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PSC69487.1 - 2.7e-08 33.7 0.0 2e-07 31.0 0.0 2.4 3 0 0 3 3 3 1 HAD-hyrolase-like HAD PF12710.7 PSC69487.1 - 0.00025 21.5 1.2 0.00075 20.0 1.2 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Ribosomal_60s PF00428.19 PSC69487.1 - 2.7 8.7 13.4 9.8 6.9 13.4 2.0 1 0 0 1 1 1 0 60s Acidic ribosomal protein SBP PF03110.14 PSC69488.1 - 1.1e-25 89.8 6.5 1.9e-25 89.0 6.5 1.4 1 0 0 1 1 1 1 SBP domain Pro_dh PF01619.18 PSC69490.1 - 5.4e-77 259.2 2.3 5e-76 256.1 2.3 2.0 1 1 0 1 1 1 1 Proline dehydrogenase EF-hand_1 PF00036.32 PSC69490.1 - 2.2e-07 29.9 0.0 7e-05 22.1 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 PSC69490.1 - 3.6e-07 30.5 0.3 8.2e-07 29.4 0.3 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PSC69490.1 - 1.6e-06 27.6 0.1 4.6e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.6 PSC69490.1 - 0.00018 21.3 0.0 0.0016 18.3 0.0 2.4 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 PSC69490.1 - 0.0045 16.4 0.0 0.0093 15.4 0.0 1.5 1 0 0 1 1 1 1 EF hand RNase_E_G PF10150.9 PSC69490.1 - 0.12 11.8 0.0 0.23 10.8 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease E/G family RVT_1 PF00078.27 PSC69491.1 - 5.4e-15 55.5 0.0 1e-14 54.6 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) EF-hand_8 PF13833.6 PSC69491.1 - 4.7e-06 26.3 0.0 1.2e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 PSC69491.1 - 1.5e-05 25.4 0.6 9.3e-05 22.8 0.2 2.5 3 0 0 3 3 3 1 EF-hand domain pair Exo_endo_phos PF03372.23 PSC69491.1 - 0.00016 21.3 0.2 0.00047 19.8 0.2 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family EF-hand_1 PF00036.32 PSC69491.1 - 0.0045 16.4 0.0 0.031 13.8 0.1 2.4 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 PSC69491.1 - 0.0067 16.3 0.0 0.47 10.5 0.0 3.0 2 0 0 2 2 2 1 EF-hand domain Apolipoprotein PF01442.18 PSC69491.1 - 0.07 13.0 8.3 0.34 10.8 0.1 3.5 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain EF-hand_5 PF13202.6 PSC69491.1 - 0.16 11.5 0.0 0.38 10.3 0.0 1.7 1 0 0 1 1 1 0 EF hand 4HBT PF03061.22 PSC69493.1 - 6.3e-16 58.5 5.3 0.00073 19.8 0.1 4.6 4 0 0 4 4 4 4 Thioesterase superfamily Adeno_VII PF03228.14 PSC69493.1 - 0.02 15.5 0.0 15 6.3 0.0 3.0 2 0 0 2 2 2 0 Adenoviral core protein VII MaoC_dehydratas PF01575.19 PSC69493.1 - 0.038 13.5 0.1 3.4 7.3 0.0 2.4 2 0 0 2 2 2 0 MaoC like domain DUF35_N PF12172.8 PSC69493.1 - 0.11 12.4 0.4 2 8.4 0.0 2.7 2 0 0 2 2 2 0 Rubredoxin-like zinc ribbon domain (DUF35_N) Hydrolase_3 PF08282.12 PSC69494.1 - 8.5e-39 133.8 0.0 1e-38 133.6 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 PSC69494.1 - 2.9e-12 46.7 0.0 4.1e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 PSC69494.1 - 0.00079 19.8 0.0 0.0013 19.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Trehalose_PPase PF02358.16 PSC69494.1 - 0.13 11.4 0.0 0.25 10.4 0.0 1.4 1 1 0 1 1 1 0 Trehalose-phosphatase Scramblase PF03803.15 PSC69495.1 - 8.9e-48 162.5 0.0 1.3e-47 162.0 0.0 1.2 1 0 0 1 1 1 1 Scramblase CTP_transf_like PF01467.26 PSC69495.1 - 0.00036 20.7 0.0 0.0012 19.0 0.0 2.0 1 1 0 1 1 1 1 Cytidylyltransferase-like SBP_bac_3 PF00497.20 PSC69495.1 - 0.13 11.6 0.1 1.2 8.5 0.0 2.4 3 0 0 3 3 3 0 Bacterial extracellular solute-binding proteins, family 3 LOR PF04525.12 PSC69495.1 - 0.16 11.5 0.0 1.4 8.4 0.0 2.1 2 0 0 2 2 2 0 LURP-one-related Ank_2 PF12796.7 PSC69496.1 - 6.7e-50 167.6 0.0 1.5e-11 44.7 0.0 4.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC69496.1 - 1.3e-35 121.3 0.1 2.2e-07 31.3 0.0 7.1 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank PF00023.30 PSC69496.1 - 4.4e-32 109.1 2.8 0.00017 21.8 0.0 8.0 7 1 1 8 8 8 7 Ankyrin repeat Ank_5 PF13857.6 PSC69496.1 - 1.2e-31 108.3 3.0 9.8e-07 28.9 0.0 5.4 2 2 3 6 6 6 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC69496.1 - 8.2e-29 96.5 0.2 0.0031 17.9 0.0 8.8 9 0 0 9 9 9 6 Ankyrin repeat DUF2384 PF09722.10 PSC69496.1 - 0.0016 18.4 0.7 0.39 10.8 0.0 3.2 3 0 0 3 3 3 1 Protein of unknown function (DUF2384) HEM4 PF02602.15 PSC69496.1 - 0.036 13.4 0.4 8.4 5.7 0.0 2.7 2 1 0 2 2 2 0 Uroporphyrinogen-III synthase HemD Mito_carr PF00153.27 PSC69497.1 - 4.5e-43 145.1 4.7 2.5e-15 56.2 0.0 4.0 3 2 0 3 3 3 3 Mitochondrial carrier protein Aminotran_1_2 PF00155.21 PSC69499.1 - 2.3e-42 145.5 0.0 1.6e-34 119.7 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 PSC69499.1 - 0.036 12.6 0.0 0.18 10.3 0.1 1.8 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 PSC69499.1 - 0.14 11.5 0.0 0.26 10.5 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_1_2 PF00155.21 PSC69500.1 - 2.3e-42 145.5 0.0 1.6e-34 119.7 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 PSC69500.1 - 0.036 12.6 0.0 0.18 10.3 0.1 1.8 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 PSC69500.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase AAA PF00004.29 PSC69501.1 - 1.3e-36 125.9 0.0 3.3e-35 121.4 0.0 2.9 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) zf-HC5HC2H PF13771.6 PSC69501.1 - 8.4e-13 48.4 10.8 2.1e-12 47.1 10.8 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 PSC69501.1 - 9.2e-11 41.9 4.7 2.4e-10 40.6 4.7 1.6 1 0 0 1 1 1 1 PHD-zinc-finger like domain AAA_lid_3 PF17862.1 PSC69501.1 - 1.7e-08 34.1 0.7 1.7e-08 34.1 0.7 3.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_22 PF13401.6 PSC69501.1 - 0.00096 19.4 0.1 0.12 12.6 0.1 2.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PSC69501.1 - 0.0044 17.4 0.2 0.0044 17.4 0.2 7.9 5 4 0 5 5 5 1 AAA ATPase domain AAA_5 PF07728.14 PSC69501.1 - 0.078 13.0 0.0 0.26 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 PSC69501.1 - 0.099 12.8 0.0 0.78 9.8 0.0 2.5 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 PSC69501.1 - 0.19 12.1 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 RNA helicase GTP_EFTU PF00009.27 PSC69502.1 - 2.6e-17 63.0 0.0 4.2e-17 62.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 PSC69502.1 - 2.3e-05 24.7 0.2 4.7e-05 23.7 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 ATP_bind_1 PF03029.17 PSC69502.1 - 0.46 10.2 1.2 21 4.8 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein PSS PF03034.15 PSC69503.1 - 5.2e-105 351.1 14.4 7.3e-105 350.6 14.4 1.2 1 0 0 1 1 1 1 Phosphatidyl serine synthase Pyridoxal_deC PF00282.19 PSC69503.1 - 3e-66 223.7 0.0 3.8e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain DUF5633 PF18656.1 PSC69505.1 - 2 8.4 4.6 0.64 10.0 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5633) DUF5054 PF16477.5 PSC69506.1 - 7.4e-32 111.3 0.0 4.9e-18 65.9 0.0 3.0 2 1 0 2 2 2 2 Domain of unknown function (DUF5054) Amino_oxidase PF01593.24 PSC69507.1 - 8.4e-75 252.8 0.5 2.9e-74 251.0 0.5 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PSC69507.1 - 7.4e-16 58.1 0.5 1.7e-15 57.0 0.5 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 PSC69507.1 - 4.8e-08 32.5 0.1 6.6e-08 32.1 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 PSC69507.1 - 1.9e-07 30.8 1.2 3.5e-07 29.9 1.2 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 PSC69507.1 - 6.3e-07 28.9 0.5 8.8e-05 21.9 0.6 3.1 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.14 PSC69507.1 - 6.9e-06 25.5 0.7 1.5e-05 24.4 0.4 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PSC69507.1 - 7e-06 25.9 1.7 7e-06 25.9 1.7 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 PSC69507.1 - 1.3e-05 24.6 0.1 2.1e-05 23.9 0.1 1.2 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 PSC69507.1 - 2.3e-05 23.3 0.4 4.1e-05 22.5 0.4 1.4 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox PF00070.27 PSC69507.1 - 2.8e-05 24.6 2.8 0.0014 19.1 0.7 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PSC69507.1 - 2.9e-05 23.5 1.7 0.00025 20.4 0.6 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 PSC69507.1 - 0.00057 19.0 2.6 0.00075 18.6 1.3 1.8 2 0 0 2 2 2 1 Lycopene cyclase protein GIDA PF01134.22 PSC69507.1 - 0.0006 19.0 0.7 0.00088 18.5 0.7 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 PSC69507.1 - 0.00086 18.7 0.2 0.0015 17.9 0.2 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain IlvN PF07991.12 PSC69507.1 - 0.063 12.8 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain NPL4 PF05021.15 PSC69507.1 - 0.19 11.1 0.0 0.27 10.5 0.0 1.1 1 0 0 1 1 1 0 NPL4 family Shikimate_DH PF01488.20 PSC69507.1 - 0.19 11.8 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF1188 PF06690.11 PSC69507.1 - 0.25 10.9 0.0 2.2 7.7 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1188) Abhydrolase_6 PF12697.7 PSC69507.1 - 5.3 7.6 8.4 0.94 10.0 3.8 1.9 1 1 0 2 2 2 0 Alpha/beta hydrolase family RVT_1 PF00078.27 PSC69508.1 - 1.1e-30 106.8 0.0 1.7e-30 106.2 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) NAD_binding_10 PF13460.6 PSC69508.1 - 9e-15 55.0 1.6 1.6e-14 54.2 1.6 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 PSC69508.1 - 0.00054 20.4 0.0 0.0013 19.2 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 PSC69508.1 - 0.0026 18.0 0.0 0.0051 17.1 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 PSC69508.1 - 0.065 12.8 0.5 0.1 12.1 0.5 1.3 1 0 0 1 1 1 0 NmrA-like family IGF2_C PF08365.11 PSC69508.1 - 0.41 10.7 1.9 4.2 7.5 0.5 2.9 3 0 0 3 3 3 0 Insulin-like growth factor II E-peptide Fe-ADH PF00465.19 PSC69509.1 - 2.8e-110 368.6 0.0 6.1e-110 367.5 0.0 1.6 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Aldedh PF00171.22 PSC69509.1 - 2.5e-24 85.6 8.4 7.2e-24 84.1 7.3 1.9 2 0 0 2 2 2 1 Aldehyde dehydrogenase family Fe-ADH_2 PF13685.6 PSC69509.1 - 4e-17 62.7 0.0 2.6e-08 33.9 0.2 2.6 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase DUF1657 PF07870.11 PSC69509.1 - 0.17 11.8 2.7 0.44 10.5 2.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) Mito_carr PF00153.27 PSC69510.1 - 2.8e-59 197.1 3.2 3.5e-20 71.7 0.0 4.4 4 0 0 4 4 4 4 Mitochondrial carrier protein TFIIA PF03153.13 PSC69512.1 - 0.33 10.9 16.3 0.077 13.0 6.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3408 PF11888.8 PSC69512.1 - 0.55 10.4 5.7 1.1 9.4 5.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) RR_TM4-6 PF06459.12 PSC69512.1 - 0.69 9.7 3.4 0.66 9.7 2.1 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 CCDC53 PF10152.9 PSC69512.1 - 1.7 9.0 7.8 9.1 6.7 4.2 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex PALP PF00291.25 PSC69513.1 - 8.6e-68 228.9 3.3 9.8e-68 228.7 3.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 PSC69513.1 - 0.084 12.9 2.8 0.16 12.0 1.3 2.2 1 1 1 2 2 2 0 Zinc-binding dehydrogenase Tmemb_14 PF03647.13 PSC69514.1 - 7e-22 78.0 9.8 8.6e-22 77.7 9.8 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C SLATT_1 PF18181.1 PSC69514.1 - 0.46 10.4 2.1 0.44 10.5 0.4 1.8 1 1 1 2 2 2 0 SMODS and SLOG-associating 2TM effector domain 1 EMC3_TMCO1 PF01956.16 PSC69515.1 - 2.3e-30 105.6 3.9 2.3e-30 105.6 3.9 2.4 1 1 1 2 2 2 1 Integral membrane protein EMC3/TMCO1-like DUF4199 PF13858.6 PSC69515.1 - 0.65 10.4 4.6 1.1 9.6 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) TFIIA PF03153.13 PSC69517.1 - 0.0034 17.5 12.8 0.004 17.2 12.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.12 PSC69517.1 - 0.0096 15.8 11.1 0.013 15.3 11.1 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 ECM1 PF05782.11 PSC69517.1 - 0.019 13.9 13.5 0.025 13.5 13.5 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) SAPS PF04499.15 PSC69517.1 - 0.053 12.3 1.9 0.053 12.3 1.9 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PAN_4 PF14295.6 PSC69517.1 - 0.057 13.3 6.5 0.17 11.8 6.5 1.8 1 1 0 1 1 1 0 PAN domain Spore_coat_CotO PF14153.6 PSC69517.1 - 0.063 13.2 14.2 0.11 12.5 14.2 1.5 1 0 0 1 1 1 0 Spore coat protein CotO Endostatin PF06482.11 PSC69517.1 - 0.57 9.6 6.1 0.82 9.1 6.1 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SLC12 PF03522.15 PSC69517.1 - 0.75 8.7 4.1 0.93 8.4 4.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 DUF2052 PF09747.9 PSC69517.1 - 0.88 9.7 14.8 1.3 9.1 14.8 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Presenilin PF01080.17 PSC69517.1 - 1.1 8.0 12.7 1.4 7.6 12.7 1.1 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 PSC69517.1 - 1.3 9.0 9.1 1.6 8.6 9.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PTPRCAP PF15713.5 PSC69517.1 - 1.6 9.0 16.4 3 8.1 16.4 1.5 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Tristanin_u2 PF16638.5 PSC69517.1 - 1.8 9.4 11.0 4 8.3 11.0 1.5 1 0 0 1 1 1 0 Unstructured region on methyltransferase between zinc-fingers Tim54 PF11711.8 PSC69517.1 - 2.2 7.0 10.7 3.5 6.3 10.7 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Plasmodium_Vir PF05795.11 PSC69517.1 - 2.4 7.5 6.6 3.2 7.1 6.6 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Neur_chan_memb PF02932.16 PSC69517.1 - 3.4 7.7 4.6 4.6 7.2 4.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 PSC69517.1 - 4.1 6.5 3.7 5.1 6.2 3.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Pox_Ag35 PF03286.14 PSC69517.1 - 4.2 7.1 12.2 7.2 6.3 12.2 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF5427 PF10310.9 PSC69517.1 - 4.5 6.1 17.3 6.4 5.6 17.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) PAT1 PF09770.9 PSC69517.1 - 6.1 5.0 15.8 7.8 4.6 15.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Lin-8 PF03353.15 PSC69517.1 - 6.7 6.2 15.5 9.8 5.6 15.5 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SpoIIP PF07454.11 PSC69517.1 - 6.7 6.1 11.4 13 5.2 10.8 1.7 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) TFIIA PF03153.13 PSC69518.1 - 0.00079 19.5 11.3 0.00095 19.3 11.3 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RskA PF10099.9 PSC69518.1 - 0.0016 18.8 8.2 0.0052 17.1 8.2 1.9 1 1 0 1 1 1 1 Anti-sigma-K factor rskA RR_TM4-6 PF06459.12 PSC69518.1 - 0.0033 17.3 7.7 0.0044 16.9 7.7 1.2 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 PepSY_TM PF03929.16 PSC69518.1 - 0.028 14.1 0.6 0.039 13.6 0.6 1.2 1 0 0 1 1 1 0 PepSY-associated TM region SAPS PF04499.15 PSC69518.1 - 0.031 13.1 0.7 0.032 13.0 0.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PAN_4 PF14295.6 PSC69518.1 - 0.058 13.3 6.6 0.18 11.8 6.6 1.8 1 1 0 1 1 1 0 PAN domain FAM176 PF14851.6 PSC69518.1 - 0.093 12.4 1.8 0.18 11.5 1.8 1.5 1 0 0 1 1 1 0 FAM176 family PTPRCAP PF15713.5 PSC69518.1 - 0.1 12.9 12.7 0.18 12.0 12.7 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DREPP PF05558.12 PSC69518.1 - 0.13 12.1 10.2 0.23 11.3 10.2 1.3 1 0 0 1 1 1 0 DREPP plasma membrane polypeptide ECM1 PF05782.11 PSC69518.1 - 0.15 11.0 14.7 0.2 10.5 14.7 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) SLC12 PF03522.15 PSC69518.1 - 0.15 11.1 2.5 0.19 10.7 2.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Endostatin PF06482.11 PSC69518.1 - 0.15 11.5 3.1 0.2 11.1 3.1 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin GAGA_bind PF06217.12 PSC69518.1 - 0.16 12.2 3.5 0.22 11.8 3.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family Suf PF05843.14 PSC69518.1 - 0.23 11.4 6.3 0.3 11.0 6.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 PSC69518.1 - 0.26 10.0 9.7 0.36 9.5 9.7 1.1 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 PSC69518.1 - 0.41 9.6 4.3 0.55 9.2 4.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Menin PF05053.13 PSC69518.1 - 0.51 8.6 3.3 0.62 8.4 3.3 1.0 1 0 0 1 1 1 0 Menin CLN3 PF02487.17 PSC69518.1 - 0.69 8.9 2.3 0.94 8.5 2.3 1.1 1 0 0 1 1 1 0 CLN3 protein SpoIIP PF07454.11 PSC69518.1 - 0.87 9.0 8.7 1.6 8.1 8.1 1.7 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) Plasmodium_Vir PF05795.11 PSC69518.1 - 0.92 8.9 3.7 1.2 8.5 3.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Neur_chan_memb PF02932.16 PSC69518.1 - 1.1 9.3 2.3 1.5 8.8 2.3 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TRAP_alpha PF03896.16 PSC69518.1 - 1.1 8.4 5.7 1.7 7.8 5.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CobT PF06213.12 PSC69518.1 - 1.3 8.4 18.0 1.9 7.8 18.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TMEM51 PF15345.6 PSC69518.1 - 1.3 8.8 12.7 6.3 6.6 12.7 1.9 1 1 0 1 1 1 0 Transmembrane protein 51 V_ATPase_I PF01496.19 PSC69518.1 - 1.6 6.6 6.4 2.1 6.2 6.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PA26 PF04636.13 PSC69518.1 - 2.1 7.2 4.5 2.8 6.8 4.5 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CPSF100_C PF13299.6 PSC69518.1 - 2.2 8.4 7.9 3.7 7.7 7.9 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Gastrin PF00918.17 PSC69518.1 - 4 8.4 5.3 12 6.9 5.3 1.9 1 1 0 1 1 1 0 Gastrin/cholecystokinin family ALMT PF11744.8 PSC69518.1 - 4.8 5.9 4.2 6.6 5.4 4.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PAT1 PF09770.9 PSC69518.1 - 9 4.4 15.5 12 4.1 15.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.7 PSC69518.1 - 9.4 4.2 12.0 13 3.8 12.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein KH_1 PF00013.29 PSC69519.1 - 2.8e-44 148.8 12.1 9.2e-15 54.2 0.3 3.3 3 0 0 3 3 3 3 KH domain KH_4 PF13083.6 PSC69519.1 - 9.3e-14 51.1 4.8 0.00015 21.5 0.1 3.4 3 0 0 3 3 3 3 KH domain MOEP19 PF16005.5 PSC69519.1 - 1.3e-12 47.5 0.0 0.0049 16.8 0.0 3.1 3 0 0 3 3 3 3 KH-like RNA-binding domain WW PF00397.26 PSC69519.1 - 9e-12 44.9 2.2 1.5e-11 44.2 2.2 1.4 1 0 0 1 1 1 1 WW domain KH_2 PF07650.17 PSC69519.1 - 4e-08 33.0 2.1 0.037 13.9 0.1 3.3 3 0 0 3 3 3 3 KH domain KH_5 PF13184.6 PSC69519.1 - 0.0056 16.7 3.2 13 6.0 0.0 3.4 3 0 0 3 3 3 1 NusA-like KH domain Glyco_hyd_101C PF17451.2 PSC69519.1 - 0.18 12.1 0.2 0.41 10.9 0.2 1.6 1 0 0 1 1 1 0 Glycosyl hydrolase 101 beta sandwich domain GILT PF03227.16 PSC69520.1 - 4.9e-22 78.2 0.0 6.7e-22 77.7 0.0 1.2 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Thioredoxin_4 PF13462.6 PSC69520.1 - 0.038 14.2 0.1 0.084 13.0 0.1 1.5 2 0 0 2 2 2 0 Thioredoxin SIR2 PF02146.17 PSC69521.1 - 1.9e-43 148.4 0.0 2.9e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 Sir2 family SAP130_C PF16014.5 PSC69522.1 - 0.19 10.8 2.2 0.25 10.4 2.2 1.2 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus PufQ PF05398.11 PSC69523.1 - 0.046 13.9 3.1 0.35 11.0 0.5 2.5 2 0 0 2 2 2 0 PufQ cytochrome subunit Ras PF00071.22 PSC69524.1 - 1.9e-46 157.6 0.0 2.8e-46 157.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PSC69524.1 - 2.4e-30 105.2 0.0 4.8e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PSC69524.1 - 2.3e-08 33.7 0.0 3.5e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Trypan_PARP PF05887.11 PSC69524.1 - 2.5e-06 27.5 20.1 2.5e-06 27.5 20.1 2.4 3 0 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) DUF4766 PF15973.5 PSC69524.1 - 0.0033 18.0 0.9 0.0033 18.0 0.9 3.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4766) Gtr1_RagA PF04670.12 PSC69524.1 - 0.0067 15.8 0.0 0.0098 15.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 PSC69524.1 - 0.013 15.4 0.0 3.5 7.5 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 PSC69524.1 - 0.042 13.9 0.0 0.073 13.2 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase NUDIX PF00293.28 PSC69526.1 - 6.9e-21 74.7 0.0 1.3e-20 73.8 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain FA_hydroxylase PF04116.13 PSC69526.1 - 4.5e-17 62.6 19.8 4.5e-17 62.6 19.8 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Abhydrolase_1 PF00561.20 PSC69527.1 - 1.9e-14 53.9 0.0 4e-14 52.9 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC69527.1 - 3.6e-09 36.3 0.0 2.1e-08 33.7 0.0 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Cutinase PF01083.22 PSC69527.1 - 0.045 13.7 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Cutinase Spc7 PF08317.11 PSC69528.1 - 0.00064 18.7 7.3 0.00064 18.7 7.3 5.5 1 1 4 5 5 5 1 Spc7 kinetochore protein TMF_DNA_bd PF12329.8 PSC69528.1 - 0.006 16.6 4.1 0.006 16.6 4.1 6.5 7 1 0 8 8 8 1 TATA element modulatory factor 1 DNA binding Amidinotransf PF02274.17 PSC69529.1 - 9.5e-49 166.3 0.1 2.9e-48 164.7 0.1 1.7 1 1 0 1 1 1 1 Amidinotransferase DUF829 PF05705.14 PSC69529.1 - 7.7e-28 98.0 0.0 1.6e-27 97.0 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) LGFP PF08310.11 PSC69529.1 - 6.2e-10 39.5 2.2 8e-05 23.1 0.2 3.7 3 0 0 3 3 3 2 LGFP repeat Peptidase_S9 PF00326.21 PSC69529.1 - 0.084 12.3 0.2 0.2 11.1 0.2 1.5 1 0 0 1 1 1 0 Prolyl oligopeptidase family Pkinase PF00069.25 PSC69530.1 - 1.1e-55 188.9 0.0 1.6e-55 188.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC69530.1 - 7.7e-35 120.4 0.0 1.2e-34 119.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RRM_1 PF00076.22 PSC69530.1 - 2.9e-15 55.8 0.0 5e-15 55.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) APH PF01636.23 PSC69530.1 - 4.6e-05 23.4 0.5 4.6e-05 23.4 0.5 3.3 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 PSC69530.1 - 0.0013 18.1 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PSC69530.1 - 0.0067 15.3 0.0 0.0095 14.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PSC69530.1 - 0.1 11.9 0.3 0.23 10.8 0.0 1.6 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PSC69530.1 - 0.26 10.2 0.0 0.37 9.7 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain Aminotran_3 PF00202.21 PSC69531.1 - 1.8e-52 178.4 0.1 9.7e-28 96.9 0.0 3.2 3 0 0 3 3 3 3 Aminotransferase class-III AAA_26 PF13500.6 PSC69531.1 - 2.2e-16 60.3 0.0 2.8e-09 37.1 0.0 2.3 1 1 0 2 2 2 2 AAA domain CbiA PF01656.23 PSC69531.1 - 0.0016 18.5 0.1 0.0026 17.8 0.1 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain NARP1 PF12569.8 PSC69532.1 - 6.5e-175 582.9 5.0 6.5e-175 582.9 5.0 3.2 3 0 0 3 3 3 1 NMDA receptor-regulated protein 1 Rad51 PF08423.11 PSC69532.1 - 4.2e-106 353.9 0.0 6.7e-106 353.2 0.0 1.3 1 0 0 1 1 1 1 Rad51 UCH PF00443.29 PSC69532.1 - 2.9e-39 135.1 0.0 5.2e-39 134.3 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PSC69532.1 - 1.7e-16 60.8 0.0 3.3e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RecA PF00154.21 PSC69532.1 - 1e-13 51.4 0.2 2.3e-13 50.2 0.1 1.6 2 0 0 2 2 2 1 recA bacterial DNA recombination protein TPR_7 PF13176.6 PSC69532.1 - 5.9e-07 29.1 15.4 0.0014 18.5 0.1 5.7 5 1 0 5 5 4 2 Tetratricopeptide repeat ATPase PF06745.13 PSC69532.1 - 2.7e-06 26.9 1.2 3.3e-06 26.6 0.0 1.7 2 0 0 2 2 1 1 KaiC TPR_2 PF07719.17 PSC69532.1 - 3.5e-06 26.7 46.9 0.00034 20.5 0.2 9.3 10 0 0 10 10 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 PSC69532.1 - 2.7e-05 23.8 10.3 0.001 18.7 0.0 4.0 3 0 0 3 3 3 1 TPR repeat TPR_14 PF13428.6 PSC69532.1 - 4.9e-05 23.8 0.5 0.0007 20.2 0.1 15.5 13 4 4 18 18 11 4 Tetratricopeptide repeat HHH_5 PF14520.6 PSC69532.1 - 0.00015 22.3 0.2 0.00048 20.7 0.2 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix domain TPR_17 PF13431.6 PSC69532.1 - 0.00028 21.0 9.4 0.0072 16.6 0.0 6.1 8 0 0 8 8 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 PSC69532.1 - 0.00035 20.3 0.4 0.00035 20.3 0.4 7.0 8 0 0 8 8 8 2 Tetratricopeptide repeat zf-MYND PF01753.18 PSC69532.1 - 0.00059 19.9 3.9 0.00059 19.9 3.9 2.6 2 0 0 2 2 2 1 MYND finger TPR_8 PF13181.6 PSC69532.1 - 0.0016 18.5 0.2 0.0016 18.5 0.2 7.7 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_19 PF14559.6 PSC69532.1 - 0.054 14.0 0.1 0.054 14.0 0.1 10.2 9 2 1 10 10 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PSC69532.1 - 0.22 11.6 6.3 2.7 8.1 0.2 3.9 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat MAM1 PF10434.9 PSC69532.1 - 0.94 9.0 4.6 2.8 7.5 4.6 1.8 1 0 0 1 1 1 0 Monopolin complex protein MAM1 Ank_4 PF13637.6 PSC69533.1 - 2e-23 82.4 1.2 1.5e-10 41.3 0.1 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PSC69533.1 - 1.1e-22 80.3 0.0 3.9e-14 53.0 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PSC69533.1 - 5e-20 69.5 0.1 3.7e-05 23.8 0.0 3.3 3 0 0 3 3 3 3 Ankyrin repeat Ank PF00023.30 PSC69533.1 - 4.9e-19 67.9 0.1 9e-06 25.9 0.0 3.2 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 PSC69533.1 - 6.7e-18 64.5 0.1 1e-06 28.9 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Response_reg PF00072.24 PSC69534.1 - 9.6e-26 90.2 1.3 2.4e-25 88.9 0.1 2.3 3 0 0 3 3 3 1 Response regulator receiver domain Myb_DNA-binding PF00249.31 PSC69534.1 - 8.8e-07 29.0 0.0 1.8e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Peptidase_M20 PF01546.28 PSC69535.1 - 2.9e-36 125.1 0.3 6e-36 124.1 0.3 1.5 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 PSC69535.1 - 5.2e-10 39.2 0.4 1.1e-08 35.0 0.0 2.6 3 0 0 3 3 3 1 Peptidase dimerisation domain TraV PF09676.10 PSC69535.1 - 0.15 13.1 1.2 0.28 12.2 1.2 1.5 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) PsbR PF04725.12 PSC69537.1 - 1.5e-43 147.1 2.3 1.8e-43 146.8 2.3 1.1 1 0 0 1 1 1 1 Photosystem II 10 kDa polypeptide PsbR BATS PF06968.13 PSC69538.1 - 8.7e-18 64.3 0.0 1.8e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 PSC69538.1 - 7.2e-14 52.5 0.0 1.1e-13 51.9 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Kelch_6 PF13964.6 PSC69538.1 - 7.7e-11 41.9 0.1 0.00048 20.3 0.0 5.4 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 PSC69538.1 - 2.7e-08 33.7 0.1 0.18 11.8 0.0 4.6 4 0 0 4 4 4 3 Galactose oxidase, central domain Kelch_1 PF01344.25 PSC69538.1 - 4e-08 32.7 0.0 0.046 13.3 0.0 4.2 4 0 0 4 4 4 3 Kelch motif Glyco_trans_4_5 PF16994.5 PSC69538.1 - 6.6e-08 32.4 0.0 1.5e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl-transferase family 4 Kelch_5 PF13854.6 PSC69538.1 - 0.0032 17.4 0.0 8.4 6.5 0.0 3.8 3 0 0 3 3 3 1 Kelch motif Fer4_12 PF13353.6 PSC69538.1 - 0.17 12.1 0.1 0.32 11.2 0.1 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Kelch_3 PF13415.6 PSC69538.1 - 0.36 11.2 12.6 43 4.6 0.0 6.5 6 1 0 6 6 6 0 Galactose oxidase, central domain Glucan_synthase PF02364.15 PSC69540.1 - 4.6e-172 574.2 7.1 6.1e-109 365.4 12.9 3.3 2 2 0 2 2 2 2 1,3-beta-glucan synthase component FKS1_dom1 PF14288.6 PSC69540.1 - 5.2e-07 30.0 0.0 3.7e-05 24.1 0.0 2.6 1 1 0 1 1 1 1 1,3-beta-glucan synthase subunit FKS1, domain-1 DUF3810 PF12725.7 PSC69540.1 - 2.8 7.2 5.7 17 4.7 5.7 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3810) SHMT PF00464.19 PSC69541.1 - 3.6e-188 625.2 0.0 4.2e-188 624.9 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Beta_elim_lyase PF01212.21 PSC69541.1 - 0.00014 21.3 0.0 0.00032 20.1 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_1_2 PF00155.21 PSC69541.1 - 0.006 15.8 0.0 0.019 14.1 0.0 1.9 1 1 0 1 1 1 1 Aminotransferase class I and II LDcluster4 PF18306.1 PSC69541.1 - 0.015 14.9 0.3 0.054 13.1 0.0 1.9 2 0 0 2 2 2 0 SLOG cluster4 family Mpv17_PMP22 PF04117.12 PSC69542.1 - 1.6e-15 57.0 0.4 1.2e-14 54.3 0.1 2.2 2 0 0 2 2 2 1 Mpv17 / PMP22 family UPF0182 PF03699.13 PSC69543.1 - 0.096 10.8 2.5 0.12 10.5 2.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) DUF5134 PF17197.4 PSC69543.1 - 1 9.3 12.2 1.7 8.5 12.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF5134) Hydantoinase_B PF02538.14 PSC69544.1 - 5.4e-215 714.7 2.1 7.4e-215 714.2 2.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 PSC69544.1 - 1.2e-100 336.6 1.4 1.2e-100 336.6 1.4 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 PSC69544.1 - 4.5e-54 182.9 0.0 2.8e-52 177.0 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region LRR_4 PF12799.7 PSC69544.1 - 2.3e-05 24.7 10.1 0.042 14.3 0.2 3.7 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC69544.1 - 0.0001 22.0 4.3 0.098 12.4 0.1 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 PSC69544.1 - 1.1 10.0 4.9 37 5.4 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat Hydantoinase_B PF02538.14 PSC69545.1 - 5.3e-215 714.7 2.1 7.4e-215 714.2 2.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 PSC69545.1 - 1.2e-100 336.6 1.4 1.2e-100 336.6 1.4 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 PSC69545.1 - 1.4e-48 164.9 0.0 9.8e-47 158.9 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region LRR_4 PF12799.7 PSC69545.1 - 1.9e-05 24.9 10.1 0.042 14.3 0.2 3.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 PSC69545.1 - 3.2e-05 24.1 1.3 3.2e-05 24.1 1.3 2.1 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 PSC69545.1 - 0.0001 22.0 4.3 0.098 12.4 0.1 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 PSC69545.1 - 1.1 10.1 4.9 37 5.4 0.0 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat Hydantoinase_B PF02538.14 PSC69546.1 - 5.5e-215 714.6 2.1 7.6e-215 714.2 2.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 PSC69546.1 - 1.2e-100 336.6 1.4 1.2e-100 336.6 1.4 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 PSC69546.1 - 4.6e-54 182.8 0.0 2.8e-52 177.0 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region LRR_4 PF12799.7 PSC69546.1 - 2.1e-05 24.8 10.1 0.043 14.3 0.2 3.8 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 PSC69546.1 - 3.2e-05 24.1 1.3 3.2e-05 24.1 1.3 2.1 3 0 0 3 3 3 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 PSC69546.1 - 0.00011 21.9 4.3 0.1 12.4 0.1 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 PSC69546.1 - 1.2 10.0 4.9 38 5.4 0.0 4.0 3 0 0 3 3 3 0 Leucine Rich Repeat Hydantoinase_B PF02538.14 PSC69547.1 - 5.5e-215 714.7 2.1 7.5e-215 714.2 2.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 PSC69547.1 - 1.2e-100 336.6 1.4 1.2e-100 336.6 1.4 1.8 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 PSC69547.1 - 4.6e-54 182.8 0.0 2.8e-52 177.0 0.0 2.4 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region LRRNT_2 PF08263.12 PSC69547.1 - 3.2e-05 24.1 1.3 3.2e-05 24.1 1.3 2.0 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 PSC69547.1 - 0.00024 21.4 6.5 0.046 14.2 0.2 3.8 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC69547.1 - 0.0011 18.7 3.1 0.1 12.4 0.1 2.5 2 0 0 2 2 2 2 Leucine rich repeat Pkinase PF00069.25 PSC69548.1 - 3.2e-61 207.0 0.0 4e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.32 PSC69548.1 - 2e-23 80.1 2.1 3.9e-05 22.9 0.0 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PSC69548.1 - 4.4e-23 81.5 1.6 2.6e-12 47.0 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PSC69548.1 - 3.1e-20 70.7 2.9 6.2e-05 22.3 0.0 4.6 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PSC69548.1 - 1.3e-19 68.3 4.7 2.9e-05 23.6 0.1 4.7 4 0 0 4 4 4 4 EF-hand domain Pkinase_Tyr PF07714.17 PSC69548.1 - 2.7e-19 69.5 0.0 8.7e-19 67.8 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase EF-hand_8 PF13833.6 PSC69548.1 - 5.3e-13 48.6 2.2 1.4e-05 24.8 0.1 4.4 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PSC69548.1 - 0.00014 22.1 0.3 0.16 12.3 0.0 2.4 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 PSC69548.1 - 0.0014 18.9 0.4 0.1 13.0 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain Kinase-like PF14531.6 PSC69548.1 - 0.0018 17.6 0.0 0.004 16.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like EF-hand_10 PF14788.6 PSC69548.1 - 0.026 14.4 0.2 3.8 7.5 0.0 2.6 2 0 0 2 2 2 0 EF hand EF-hand_4 PF12763.7 PSC69548.1 - 0.28 11.2 1.4 1.7 8.6 0.1 2.3 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Gp_dh_C PF02800.20 PSC69550.1 - 3.7e-57 192.3 0.0 5.4e-57 191.8 0.0 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 PSC69550.1 - 1.5e-24 86.2 0.0 3.7e-24 85.0 0.0 1.7 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Methyltransf_24 PF13578.6 PSC69551.1 - 0.00037 21.5 0.2 0.0013 19.7 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain zf-NOSIP PF15906.5 PSC69552.1 - 4.8e-11 42.7 0.0 1.3e-10 41.3 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein RINGv PF12906.7 PSC69552.1 - 1.1e-05 25.4 6.9 2.6e-05 24.3 6.9 1.7 1 0 0 1 1 1 1 RING-variant domain U-box PF04564.15 PSC69552.1 - 0.0013 18.9 0.0 0.019 15.2 0.0 2.3 2 0 0 2 2 2 1 U-box domain zf-RING_2 PF13639.6 PSC69552.1 - 0.55 10.6 5.6 1.5 9.2 5.6 1.8 1 0 0 1 1 1 0 Ring finger domain ATP-synt_C PF00137.21 PSC69554.1 - 2.5e-31 107.8 49.7 3e-20 72.3 16.2 3.5 4 0 0 4 4 4 2 ATP synthase subunit C PAP2_C PF14360.6 PSC69554.1 - 6e-21 74.8 7.1 6e-21 74.8 7.1 2.4 2 0 0 2 2 2 1 PAP2 superfamily C-terminal PAP2_3 PF14378.6 PSC69554.1 - 4.8e-05 23.1 11.9 4.8e-05 23.1 11.9 2.9 2 1 0 2 2 2 1 PAP2 superfamily PAP2 PF01569.21 PSC69554.1 - 0.00044 20.0 4.0 0.00044 20.0 4.0 3.8 3 1 1 4 4 4 1 PAP2 superfamily Pkinase PF00069.25 PSC69555.1 - 6.8e-37 127.3 0.0 2.9e-36 125.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC69555.1 - 1.5e-31 109.6 0.0 1e-30 106.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PSC69555.1 - 2.2e-05 24.1 2.4 1.6 8.6 1.1 5.2 6 0 0 6 6 6 2 Leucine rich repeat LRR_4 PF12799.7 PSC69555.1 - 0.0012 19.2 1.0 24 5.5 0.0 5.2 5 2 1 6 6 6 1 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 PSC69555.1 - 0.0052 17.1 0.4 0.012 15.9 0.4 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Glyco_transf_20 PF00982.21 PSC69557.1 - 5.3e-161 536.5 0.0 6.5e-161 536.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 PSC69557.1 - 1.2e-75 253.6 0.0 1.7e-75 253.2 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 PSC69557.1 - 0.0012 18.6 0.0 0.16 11.7 0.0 2.2 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Glyco_transf_4 PF13439.6 PSC69557.1 - 0.022 14.8 0.1 0.062 13.3 0.1 1.8 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 PSC69557.1 - 0.079 12.5 0.0 14 5.1 0.0 3.2 3 0 0 3 3 3 0 Glycosyl transferases group 1 PD40 PF07676.12 PSC69558.1 - 4.2e-36 122.2 12.0 7.7e-09 35.3 0.0 5.6 5 0 0 5 5 5 5 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 PSC69558.1 - 1.5e-05 23.9 0.5 0.72 8.5 0.0 4.3 3 1 0 4 4 4 3 Dipeptidyl peptidase IV (DPP IV) N-terminal region Ge1_WD40 PF16529.5 PSC69558.1 - 0.048 12.6 0.1 0.42 9.5 0.0 2.3 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 PSC69558.1 - 0.12 12.7 0.2 92 3.4 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain MSP PF01716.18 PSC69559.1 - 2.8e-58 197.0 0.0 3.6e-58 196.6 0.0 1.1 1 0 0 1 1 1 1 Manganese-stabilising protein / photosystem II polypeptide RRM_1 PF00076.22 PSC69560.1 - 3.9e-23 81.0 0.0 8.6e-23 80.0 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSD PF00313.22 PSC69560.1 - 0.01 15.7 0.1 0.019 14.8 0.1 1.4 1 0 0 1 1 1 0 'Cold-shock' DNA-binding domain Limkain-b1 PF11608.8 PSC69560.1 - 0.074 13.1 0.1 0.25 11.4 0.1 1.8 1 1 0 1 1 1 0 Limkain b1 HAD_2 PF13419.6 PSC69561.1 - 7.7e-24 84.7 0.0 9.1e-24 84.5 0.0 1.0 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PSC69561.1 - 4.7e-17 63.0 1.0 3.1e-15 57.0 1.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PSC69561.1 - 2.1e-05 25.0 0.7 6.9e-05 23.3 0.7 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PSC69561.1 - 0.029 14.4 0.1 0.16 12.1 0.0 2.2 3 0 0 3 3 3 0 HAD-hyrolase-like Hydrolase_3 PF08282.12 PSC69561.1 - 0.23 11.2 0.0 22 4.6 0.0 2.1 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase UbiA PF01040.18 PSC69563.1 - 9.3e-37 126.7 23.5 1.7e-36 125.8 23.5 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family GST_N_3 PF13417.6 PSC69564.1 - 7.7e-18 64.7 0.0 1.3e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PSC69564.1 - 1.5e-15 57.2 0.0 2.3e-15 56.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PSC69564.1 - 4.3e-09 36.3 0.1 8.3e-09 35.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PSC69564.1 - 2.8e-07 30.8 0.0 5e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 PSC69564.1 - 0.00037 21.1 0.0 0.00063 20.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PSC69564.1 - 0.0013 18.9 0.0 0.003 17.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PSC69564.1 - 0.051 13.8 0.0 0.089 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 PSC69564.1 - 0.14 12.4 0.0 0.59 10.4 0.0 1.9 2 0 0 2 2 2 0 Glutaredoxin UCR_UQCRX_QCR9 PF05365.12 PSC69565.1 - 1.3e-20 73.1 0.1 1.4e-20 73.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Alpha-amyl_C2 PF07821.12 PSC69565.1 - 0.11 12.7 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Alpha-amylase C-terminal beta-sheet domain zf-DNL PF05180.12 PSC69566.1 - 5.8e-12 45.4 0.0 8.5e-12 44.8 0.0 1.2 1 0 0 1 1 1 1 DNL zinc finger zf-Sec23_Sec24 PF04810.15 PSC69566.1 - 1.2 9.3 2.8 3.2 7.9 0.1 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger zf-RING_2 PF13639.6 PSC69567.1 - 2.1e-07 31.2 0.6 5e-07 30.0 0.6 1.7 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PSC69567.1 - 1.6e-06 28.3 2.3 3.5e-06 27.2 2.3 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PSC69567.1 - 3.7e-05 23.5 0.5 6.9e-05 22.6 0.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC69567.1 - 0.00055 19.8 0.9 0.0012 18.8 0.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 PSC69567.1 - 0.00091 18.9 2.4 0.0038 16.9 0.5 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-ANAPC11 PF12861.7 PSC69567.1 - 0.0014 18.6 1.7 0.003 17.6 1.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 PSC69567.1 - 0.011 15.5 4.1 0.011 15.5 4.1 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PSC69567.1 - 0.011 15.5 1.6 0.011 15.5 1.6 1.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 PSC69567.1 - 0.043 13.4 2.9 0.11 12.1 2.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 PSC69567.1 - 0.12 12.4 2.9 0.29 11.2 2.9 1.7 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.7 PSC69567.1 - 0.14 12.2 0.4 0.31 11.1 0.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_4 PF15227.6 PSC69567.1 - 0.61 10.3 3.7 1.2 9.3 3.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Rhomboid PF01694.22 PSC69569.1 - 5e-16 59.1 1.3 6.7e-16 58.6 0.4 1.7 2 0 0 2 2 2 1 Rhomboid family DUF829 PF05705.14 PSC69570.1 - 2.6e-30 106.1 0.0 3.9e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) PfkB PF00294.24 PSC69570.1 - 5.8e-13 48.8 0.3 1.1e-12 47.9 0.3 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Peptidase_S9 PF00326.21 PSC69570.1 - 0.1 12.1 0.3 0.96 8.9 0.1 2.3 2 1 0 2 2 2 0 Prolyl oligopeptidase family ATP-synt PF00231.19 PSC69571.1 - 5.1e-85 285.6 0.7 7.3e-85 285.1 0.7 1.2 1 0 0 1 1 1 1 ATP synthase Pkinase PF00069.25 PSC69573.1 - 1.4e-51 175.4 0.0 1.8e-51 175.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC69573.1 - 1.2e-17 64.1 0.0 1.7e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PSC69573.1 - 0.0028 17.0 0.0 0.0095 15.3 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PSC69573.1 - 0.0096 15.9 0.4 0.065 13.2 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family EF-hand_7 PF13499.6 PSC69573.1 - 0.03 14.8 0.0 0.68 10.4 0.0 2.7 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_8 PF13833.6 PSC69573.1 - 0.1 12.5 0.0 0.78 9.6 0.0 2.5 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_6 PF13405.6 PSC69573.1 - 0.12 12.3 0.0 17 5.6 0.0 3.7 4 0 0 4 4 4 0 EF-hand domain Kinase-like PF14531.6 PSC69573.1 - 0.22 10.8 0.2 1.9 7.7 0.1 2.4 2 1 0 2 2 2 0 Kinase-like ELFV_dehydrog PF00208.21 PSC69575.1 - 5e-80 268.7 2.8 6.2e-80 268.4 2.8 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 PSC69575.1 - 4.9e-49 165.5 0.0 2.1e-48 163.5 0.0 2.1 3 0 0 3 3 3 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 PSC69575.1 - 0.002 18.5 0.0 0.0039 17.6 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 PSC69575.1 - 0.053 13.6 0.3 0.11 12.5 0.3 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain ELFV_dehydrog PF00208.21 PSC69576.1 - 4.7e-80 268.8 2.8 5.7e-80 268.5 2.8 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 PSC69576.1 - 4.5e-49 165.6 0.0 2e-48 163.6 0.0 2.1 3 0 0 3 3 3 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 PSC69576.1 - 0.002 18.6 0.0 0.0037 17.7 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 PSC69576.1 - 0.052 13.6 0.3 0.11 12.6 0.3 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain CBFD_NFYB_HMF PF00808.23 PSC69577.1 - 1.8e-20 73.0 0.2 3.7e-20 72.0 0.2 1.6 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PSC69577.1 - 2.2e-14 53.9 0.1 2.2e-14 53.9 0.1 2.0 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIIA PF03153.13 PSC69577.1 - 0.018 15.1 14.2 0.028 14.4 14.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 PSC69577.1 - 0.05 12.5 6.7 0.064 12.2 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Med3 PF11593.8 PSC69577.1 - 0.071 12.3 17.6 0.099 11.8 17.6 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Pex14_N PF04695.13 PSC69577.1 - 0.09 13.4 9.8 0.15 12.7 9.8 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Dehydrin PF00257.19 PSC69577.1 - 0.21 12.1 2.5 0.35 11.4 2.5 1.3 1 0 0 1 1 1 0 Dehydrin CENP-X PF09415.10 PSC69577.1 - 0.64 10.4 3.5 1.6 9.1 0.1 2.3 2 0 0 2 2 2 0 CENP-S associating Centromere protein X FAM70 PF14967.6 PSC69577.1 - 2.4 7.5 5.2 3.1 7.2 5.2 1.2 1 0 0 1 1 1 0 FAM70 protein DUF3450 PF11932.8 PSC69577.1 - 4.5 6.5 18.0 8.1 5.7 18.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Spt20 PF12090.8 PSC69577.1 - 6.5 6.3 18.6 10 5.6 18.6 1.2 1 0 0 1 1 1 0 Spt20 family Med12 PF09497.10 PSC69578.1 - 0.00057 20.1 0.2 0.0017 18.6 0.2 1.9 1 1 0 1 1 1 1 Transcription mediator complex subunit Med12 EGF_2 PF07974.13 PSC69579.1 - 2.2 8.7 73.4 0.044 14.2 11.2 6.6 6 0 0 6 6 6 0 EGF-like domain DivIC PF04977.15 PSC69580.1 - 0.62 9.9 4.0 6.8 6.5 1.2 2.4 2 0 0 2 2 2 0 Septum formation initiator JIP_LZII PF16471.5 PSC69580.1 - 4 7.7 5.0 1.7 8.8 1.8 1.9 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II KH_8 PF17903.1 PSC69581.1 - 2.8e-32 110.7 0.0 4.8e-32 109.9 0.0 1.4 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 PSC69581.1 - 0.0011 18.8 0.0 0.0022 17.8 0.0 1.5 1 0 0 1 1 1 1 KH domain UDPGP PF01704.18 PSC69582.1 - 1.7e-39 135.7 0.0 2.2e-39 135.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 PSC69582.1 - 0.0039 17.6 0.5 0.019 15.3 0.2 2.5 1 1 0 2 2 2 1 MobA-like NTP transferase domain DUF4126 PF13548.6 PSC69582.1 - 0.0044 16.7 0.4 0.0078 15.9 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4126) Lactamase_B_5 PF14597.6 PSC69582.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily UDPGP PF01704.18 PSC69583.1 - 2.2e-39 135.3 0.0 3e-39 134.8 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase DUF4126 PF13548.6 PSC69583.1 - 0.005 16.6 0.4 0.0093 15.7 0.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4126) NTP_transf_3 PF12804.7 PSC69583.1 - 0.0052 17.1 0.6 0.022 15.1 0.6 2.4 1 1 0 1 1 1 1 MobA-like NTP transferase domain Lactamase_B_5 PF14597.6 PSC69583.1 - 0.13 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily GrpE PF01025.19 PSC69585.1 - 7.1e-41 139.6 0.9 8.3e-41 139.4 0.1 1.5 2 0 0 2 2 2 1 GrpE APG17 PF04108.12 PSC69585.1 - 0.0015 17.7 0.6 0.002 17.3 0.6 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 MPS2 PF17060.5 PSC69585.1 - 0.022 14.0 0.8 0.03 13.6 0.8 1.1 1 0 0 1 1 1 0 Monopolar spindle protein 2 CLZ PF16526.5 PSC69585.1 - 0.027 14.8 1.1 0.092 13.1 1.1 1.8 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RasGAP_C PF03836.15 PSC69585.1 - 0.053 13.7 0.4 7.6 6.7 0.0 2.2 2 0 0 2 2 2 0 RasGAP C-terminus TPR_MLP1_2 PF07926.12 PSC69585.1 - 0.06 13.4 3.3 0.1 12.6 3.3 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein CHZ PF09649.10 PSC69587.1 - 5.9e-08 32.0 2.1 2.5e-07 30.0 2.1 2.1 1 0 0 1 1 1 1 Histone chaperone domain CHZ DEK_C PF08766.11 PSC69587.1 - 0.033 14.1 0.2 0.1 12.5 0.1 1.9 2 0 0 2 2 2 0 DEK C terminal domain Serglycin PF04360.12 PSC69587.1 - 1.1 9.2 19.2 0.23 11.4 0.7 2.8 3 0 0 3 3 3 0 Serglycin VIT1 PF01988.19 PSC69588.1 - 5e-59 199.8 4.9 7.5e-59 199.2 4.9 1.3 1 0 0 1 1 1 1 VIT family Alpha-amylase PF00128.24 PSC69588.1 - 2.2e-20 73.5 0.1 4.4e-14 52.8 0.1 3.6 2 1 1 3 3 3 3 Alpha amylase, catalytic domain CBM_48 PF02922.18 PSC69588.1 - 7.5e-16 58.3 0.3 5.7e-15 55.4 0.0 2.6 2 1 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) GHL10 PF02638.15 PSC69588.1 - 0.17 10.9 0.0 0.29 10.2 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase-like 10 Pyr_redox_2 PF07992.14 PSC69589.1 - 2.2e-54 184.7 1.0 2.2e-54 184.7 1.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NIF PF03031.18 PSC69589.1 - 1.4e-39 135.4 0.2 2.2e-39 134.7 0.2 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Pyr_redox_dim PF02852.22 PSC69589.1 - 9.5e-28 96.7 0.5 5.2e-27 94.3 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 PSC69589.1 - 5.2e-16 59.0 2.3 1.1e-14 54.8 0.0 3.4 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase MatE PF01554.18 PSC69589.1 - 2.1e-08 34.0 22.8 0.0008 19.1 2.7 3.4 3 0 0 3 3 3 3 MatE FAD_binding_2 PF00890.24 PSC69589.1 - 0.00013 21.2 0.9 0.0012 18.1 0.3 3.2 3 0 0 3 3 2 2 FAD binding domain GIDA PF01134.22 PSC69589.1 - 0.00028 20.1 2.0 0.00028 20.1 2.0 2.4 3 0 0 3 3 2 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 PSC69589.1 - 0.0046 16.4 0.9 0.0046 16.4 0.9 2.4 2 0 0 2 2 1 1 FAD dependent oxidoreductase 3HCDH_N PF02737.18 PSC69589.1 - 0.0051 16.7 0.1 1.5 8.7 0.0 2.4 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K_oxygenase PF13434.6 PSC69589.1 - 0.023 13.9 0.0 0.057 12.6 0.0 1.6 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) 2-Hacid_dh_C PF02826.19 PSC69589.1 - 0.05 13.0 0.0 1 8.7 0.0 2.5 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 PSC69589.1 - 0.059 12.9 0.1 0.11 12.1 0.1 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DIM PF08194.12 PSC69589.1 - 0.18 12.0 1.9 1.5 9.1 1.9 2.8 1 0 0 1 1 1 0 DIM protein BHD_3 PF10405.9 PSC69590.1 - 7.3e-22 77.6 0.1 1.3e-21 76.8 0.1 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 PSC69590.1 - 2.6e-15 56.4 0.0 6.3e-15 55.1 0.0 1.6 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain BHD_2 PF10404.9 PSC69590.1 - 2.9e-09 37.7 0.1 2.9e-09 37.7 0.1 4.8 5 0 0 5 5 5 1 Rad4 beta-hairpin domain 2 BHD_1 PF10403.9 PSC69590.1 - 1.3e-08 34.5 0.0 2.2e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 1 RRP7 PF12923.7 PSC69590.1 - 0.0015 18.7 0.1 0.0015 18.7 0.1 2.4 3 0 0 3 3 3 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Transglut_core PF01841.19 PSC69590.1 - 0.027 14.9 3.4 0.17 12.3 0.9 3.0 2 0 0 2 2 2 0 Transglutaminase-like superfamily PrmA PF06325.13 PSC69590.1 - 0.84 9.0 4.4 0.6 9.4 1.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Peptidase_M3 PF01432.20 PSC69592.1 - 3.2e-18 66.3 0.0 8.5e-17 61.6 0.0 2.2 1 1 0 1 1 1 1 Peptidase family M3 Peptidase_M2 PF01401.18 PSC69592.1 - 4.2e-10 38.9 0.5 6.1e-10 38.4 0.5 1.1 1 0 0 1 1 1 1 Angiotensin-converting enzyme ADK PF00406.22 PSC69593.1 - 2.5e-35 121.8 0.0 6.2e-35 120.5 0.0 1.7 2 0 0 2 2 2 1 Adenylate kinase Glycos_transf_1 PF00534.20 PSC69593.1 - 2.8e-21 75.8 0.0 4.9e-21 75.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 AAA_17 PF13207.6 PSC69593.1 - 1.5e-15 57.8 0.0 3.3e-15 56.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain Glyco_trans_1_4 PF13692.6 PSC69593.1 - 5.4e-13 49.5 0.0 1.4e-12 48.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Sucrose_synth PF00862.19 PSC69593.1 - 1.1e-08 33.9 0.0 1.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Sucrose synthase Glyco_trans_1_2 PF13524.6 PSC69593.1 - 1.2e-05 25.5 0.0 3.6e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 S6PP PF05116.13 PSC69593.1 - 0.0016 18.0 0.0 0.098 12.2 0.0 2.9 3 0 0 3 3 3 1 Sucrose-6F-phosphate phosphohydrolase Glyco_transf_4 PF13439.6 PSC69593.1 - 0.0023 18.0 0.2 0.013 15.5 0.0 2.4 2 0 0 2 2 2 1 Glycosyltransferase Family 4 ADK_lid PF05191.14 PSC69593.1 - 0.014 15.4 0.0 0.033 14.2 0.0 1.7 1 0 0 1 1 1 0 Adenylate kinase, active site lid AAA_18 PF13238.6 PSC69593.1 - 0.096 13.2 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF1752 PF08550.10 PSC69593.1 - 0.11 12.4 0.1 0.28 11.1 0.1 1.7 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1752) AAA_33 PF13671.6 PSC69593.1 - 0.15 12.3 0.0 0.6 10.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Fructosamin_kin PF03881.14 PSC69594.1 - 7.5e-75 251.8 0.0 7.5e-75 251.8 0.0 2.2 3 0 0 3 3 3 1 Fructosamine kinase bZIP_1 PF00170.21 PSC69594.1 - 0.006 16.7 5.2 0.006 16.7 5.2 3.0 3 0 0 3 3 3 2 bZIP transcription factor Presenilin PF01080.17 PSC69594.1 - 0.31 9.8 13.5 0.6 8.8 13.5 1.4 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 PSC69594.1 - 1.9 6.5 15.4 3 5.9 15.4 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein TFIIA PF03153.13 PSC69594.1 - 5 7.0 38.4 0.046 13.7 25.9 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SWIM PF04434.17 PSC69595.1 - 0.0005 19.7 3.5 0.0013 18.4 3.5 1.7 1 0 0 1 1 1 1 SWIM zinc finger DUF913 PF06025.12 PSC69595.1 - 0.0022 17.1 7.2 0.0032 16.5 7.2 1.2 1 0 0 1 1 1 1 Domain of Unknown Function (DUF913) EIF4E-T PF10477.9 PSC69595.1 - 0.052 12.4 16.9 0.07 11.9 16.9 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Smg8_Smg9 PF10220.9 PSC69595.1 - 0.1 10.9 9.2 0.13 10.5 9.2 1.0 1 0 0 1 1 1 0 Smg8_Smg9 RPN2_C PF18004.1 PSC69595.1 - 0.12 12.3 16.2 0.23 11.4 16.2 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SpoIIP PF07454.11 PSC69595.1 - 0.18 11.3 16.9 0.37 10.2 16.9 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Tim54 PF11711.8 PSC69595.1 - 0.18 10.5 16.0 0.34 9.6 16.0 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Coilin_N PF15862.5 PSC69595.1 - 0.2 11.4 13.9 0.4 10.5 13.9 1.5 1 0 0 1 1 1 0 Coilin N-terminus EPL1 PF10513.9 PSC69595.1 - 0.2 12.0 13.4 0.36 11.2 13.4 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like eIF-3_zeta PF05091.12 PSC69595.1 - 0.22 10.5 16.0 0.3 10.0 16.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.13 PSC69595.1 - 0.29 11.1 45.0 0.42 10.5 45.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAPS PF04499.15 PSC69595.1 - 0.33 9.7 10.2 0.44 9.3 10.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NPR3 PF03666.13 PSC69595.1 - 0.4 9.4 13.0 0.56 8.9 13.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF4770 PF15994.5 PSC69595.1 - 0.51 10.6 13.9 1 9.6 13.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF4820 PF16091.5 PSC69595.1 - 0.55 9.5 11.3 0.85 8.9 11.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) GREB1 PF15782.5 PSC69595.1 - 0.58 7.2 10.2 0.75 6.9 10.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer PA26 PF04636.13 PSC69595.1 - 0.65 8.9 8.1 0.83 8.5 8.1 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Presenilin PF01080.17 PSC69595.1 - 0.66 8.7 19.5 1 8.0 19.5 1.2 1 0 0 1 1 1 0 Presenilin FAM176 PF14851.6 PSC69595.1 - 0.75 9.4 10.2 1.2 8.8 10.2 1.3 1 0 0 1 1 1 0 FAM176 family Endostatin PF06482.11 PSC69595.1 - 0.95 8.9 14.6 1.5 8.2 14.6 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF4746 PF15928.5 PSC69595.1 - 1.1 8.6 17.2 1.7 8.0 17.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TRAP_alpha PF03896.16 PSC69595.1 - 1.2 8.2 9.1 1.9 7.7 9.1 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2151 PF10221.9 PSC69595.1 - 1.3 7.5 6.5 1.8 7.1 6.5 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator ABC2_membrane_2 PF12679.7 PSC69595.1 - 1.7 7.9 3.2 2.5 7.3 3.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein SID-1_RNA_chan PF13965.6 PSC69595.1 - 1.7 7.0 5.3 2.1 6.7 5.3 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Plasmodium_Vir PF05795.11 PSC69595.1 - 1.7 8.0 8.3 2.5 7.4 8.3 1.2 1 0 0 1 1 1 0 Plasmodium vivax Vir protein FAM91_C PF14648.6 PSC69595.1 - 1.8 7.3 5.9 2.5 6.8 5.9 1.1 1 0 0 1 1 1 0 FAM91 C-terminus CPSF100_C PF13299.6 PSC69595.1 - 2.1 8.5 17.2 0.34 11.1 13.1 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal BORG_CEP PF14957.6 PSC69595.1 - 2.2 9.4 16.6 0.25 12.5 10.8 2.1 2 0 0 2 2 2 0 Cdc42 effector DUF2126 PF09899.9 PSC69595.1 - 2.4 6.1 10.5 3.2 5.7 10.5 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) MAJIN PF15077.6 PSC69595.1 - 2.5 7.8 9.5 4.8 6.9 9.5 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein DUF4471 PF14740.6 PSC69595.1 - 3.1 6.9 9.0 4.2 6.5 9.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4471) Hid1 PF12722.7 PSC69595.1 - 3.3 5.7 16.3 4.3 5.4 16.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RR_TM4-6 PF06459.12 PSC69595.1 - 3.3 7.4 21.9 0.34 10.7 17.6 1.4 2 0 0 2 2 1 0 Ryanodine Receptor TM 4-6 Spt20 PF12090.8 PSC69595.1 - 3.6 7.1 44.7 6.7 6.3 44.7 1.3 1 0 0 1 1 1 0 Spt20 family CobT PF06213.12 PSC69595.1 - 3.6 6.9 29.5 6.3 6.1 29.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SLC12 PF03522.15 PSC69595.1 - 3.7 6.5 14.3 5.2 6.0 14.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Rtf2 PF04641.12 PSC69595.1 - 3.9 6.8 13.9 7.2 5.9 13.9 1.4 1 0 0 1 1 1 0 Rtf2 RING-finger CTU2 PF10288.9 PSC69595.1 - 5.5 7.3 12.9 12 6.1 12.9 1.5 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Lin-8 PF03353.15 PSC69595.1 - 5.8 6.4 19.2 8.9 5.8 19.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Peptidase_S64 PF08192.11 PSC69595.1 - 6.2 5.2 12.8 8.5 4.7 12.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 NARP1 PF12569.8 PSC69595.1 - 7.1 5.4 20.5 9.8 4.9 20.5 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Eapp_C PF10238.9 PSC69595.1 - 7.4 6.6 16.9 17 5.5 16.9 1.5 1 0 0 1 1 1 0 E2F-associated phosphoprotein CLN3 PF02487.17 PSC69595.1 - 8 5.4 11.8 11 4.9 11.8 1.1 1 0 0 1 1 1 0 CLN3 protein Asp-B-Hydro_N PF05279.11 PSC69595.1 - 8.1 6.4 15.3 13 5.7 15.3 1.3 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Rrn6 PF10214.9 PSC69595.1 - 8.4 4.8 25.9 12 4.3 25.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor EOS1 PF12326.8 PSC69595.1 - 8.5 6.3 6.9 14 5.6 6.9 1.2 1 0 0 1 1 1 0 N-glycosylation protein PTPRCAP PF15713.5 PSC69595.1 - 8.8 6.6 21.8 28 5.0 21.8 1.8 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Ribosomal_S18 PF01084.20 PSC69597.1 - 0.0031 17.7 0.0 0.0044 17.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S18 GNT-I PF03071.15 PSC69598.1 - 1.8e-68 231.3 0.0 3e-68 230.6 0.0 1.2 1 0 0 1 1 1 1 GNT-I family Glyco_transf_18 PF15024.6 PSC69598.1 - 1.3e-08 33.9 4.6 1.8e-08 33.5 4.6 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 18 Glyco_tranf_2_3 PF13641.6 PSC69598.1 - 4.8e-05 23.3 0.0 0.00085 19.3 0.0 2.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 MGAT2 PF05060.14 PSC69598.1 - 0.0015 17.7 0.0 0.82 8.7 0.0 2.4 2 0 0 2 2 2 2 N-acetylglucosaminyltransferase II (MGAT2) Glycos_transf_2 PF00535.26 PSC69598.1 - 0.015 15.2 0.0 0.05 13.4 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 Methyltransf_11 PF08241.12 PSC69600.1 - 1e-12 48.5 0.0 2.2e-12 47.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC69600.1 - 1.4e-07 32.1 0.0 3.1e-07 31.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC69600.1 - 1.2e-05 25.2 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC69600.1 - 2e-05 25.2 0.0 3.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC69600.1 - 0.00015 21.6 0.0 0.00039 20.3 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain MetW PF07021.12 PSC69600.1 - 0.012 15.3 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Vmethyltransf PF01660.17 PSC69600.1 - 0.055 12.3 0.0 0.073 11.9 0.0 1.1 1 0 0 1 1 1 0 Viral methyltransferase Methyltransf_8 PF05148.15 PSC69600.1 - 0.19 11.5 0.0 0.28 11.0 0.0 1.2 1 0 0 1 1 1 0 Hypothetical methyltransferase Methyltransf_29 PF03141.16 PSC69600.1 - 0.25 9.9 0.0 0.33 9.4 0.0 1.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase YrhK PF14145.6 PSC69601.1 - 0.47 10.4 19.7 1.6 8.6 0.1 4.6 4 1 0 4 4 4 0 YrhK-like protein Pkinase PF00069.25 PSC69602.1 - 5.1e-46 157.2 0.0 4.8e-45 154.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC69602.1 - 3.5e-17 62.5 0.0 2.3e-13 50.0 0.0 2.4 3 0 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 PSC69602.1 - 0.00022 20.7 0.2 0.00043 19.7 0.2 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PSC69602.1 - 0.0019 17.5 0.1 0.0038 16.6 0.0 1.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 PSC69602.1 - 0.0035 17.3 1.8 0.0035 17.3 1.8 2.2 2 1 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 PSC69602.1 - 0.033 13.8 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 RIO1 family Seadorna_VP7 PF07387.11 PSC69602.1 - 0.33 10.0 0.0 0.5 9.4 0.0 1.3 1 1 0 1 1 1 0 Seadornavirus VP7 Pyr_redox_2 PF07992.14 PSC69603.1 - 1.1e-38 133.1 0.1 1.6e-38 132.6 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PSC69603.1 - 1.7e-11 44.5 0.2 5e-09 36.6 0.4 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PSC69603.1 - 2.1e-05 24.7 0.5 0.019 15.2 0.0 3.0 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 PSC69603.1 - 0.0001 22.3 0.3 0.95 9.4 0.0 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding Trp_halogenase PF04820.14 PSC69603.1 - 0.0018 17.2 0.3 0.033 13.1 0.5 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.12 PSC69603.1 - 0.0026 16.9 0.2 0.11 11.6 0.2 2.8 3 0 0 3 3 3 1 Lycopene cyclase protein HI0933_like PF03486.14 PSC69603.1 - 0.061 12.0 0.0 7.3 5.2 0.3 2.2 2 0 0 2 2 2 0 HI0933-like protein K_oxygenase PF13434.6 PSC69603.1 - 0.093 11.9 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.22 PSC69603.1 - 0.11 11.6 2.2 0.063 12.4 0.4 1.6 2 0 0 2 2 2 0 Glucose inhibited division protein A ABC_tran PF00005.27 PSC69604.1 - 9.1e-24 84.5 0.2 2.8e-23 83.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC2_membrane PF01061.24 PSC69604.1 - 6.6e-09 35.5 15.9 6.6e-09 35.5 15.9 1.9 3 0 0 3 3 3 1 ABC-2 type transporter AAA_21 PF13304.6 PSC69604.1 - 0.0011 18.9 0.2 0.97 9.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PSC69604.1 - 0.0039 16.9 0.3 0.009 15.7 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 PSC69604.1 - 0.023 14.6 0.1 0.044 13.7 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase Y_phosphatase3 PF13350.6 PSC69604.1 - 0.042 13.8 0.5 0.11 12.5 0.2 1.7 2 0 0 2 2 2 0 Tyrosine phosphatase family AAA_23 PF13476.6 PSC69604.1 - 0.052 14.0 0.0 0.09 13.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PSC69604.1 - 0.056 13.8 1.9 0.13 12.6 0.1 2.6 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 PSC69604.1 - 0.18 11.8 0.4 0.3 11.1 0.4 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain SMC_N PF02463.19 PSC69604.1 - 0.22 10.9 0.0 0.55 9.6 0.0 1.5 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Lys_export PF03956.13 PSC69604.1 - 1.4 8.5 10.5 4 6.9 8.7 2.2 1 1 1 2 2 2 0 Lysine exporter LysO Pkinase PF00069.25 PSC69605.1 - 2.7e-71 240.0 0.0 3.5e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC69605.1 - 2.1e-35 122.3 0.0 2.7e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC69605.1 - 2e-06 27.4 0.2 2e-05 24.1 0.1 2.2 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 PSC69605.1 - 5e-06 25.7 1.9 1.5e-05 24.1 1.9 1.7 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 PSC69605.1 - 7.5e-05 22.2 1.4 0.00013 21.4 1.4 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PSC69605.1 - 0.00035 19.5 0.5 0.0014 17.5 0.0 2.1 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 PSC69605.1 - 0.0022 18.0 0.2 0.15 11.9 0.0 2.6 2 1 1 3 3 3 1 Phosphotransferase enzyme family EF-G-binding_N PF07299.11 PSC69605.1 - 0.0063 17.0 0.2 0.62 10.6 0.4 2.6 2 0 0 2 2 2 1 Elongation factor G-binding protein, N-terminal FeoB_N PF02421.18 PSC69605.1 - 0.035 13.6 0.7 0.32 10.5 0.8 2.0 1 1 1 2 2 2 0 Ferrous iron transport protein B FTA2 PF13095.6 PSC69605.1 - 0.2 11.3 1.7 6.4 6.3 0.1 2.4 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DAGK_cat PF00781.24 PSC69606.1 - 4.4e-19 68.3 0.5 1.5e-18 66.7 0.1 2.1 2 0 0 2 2 2 1 Diacylglycerol kinase catalytic domain Pkinase PF00069.25 PSC69607.1 - 1.8e-60 204.6 0.0 8.2e-42 143.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC69607.1 - 1.6e-28 99.7 0.0 3.6e-22 78.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 PSC69607.1 - 0.00056 19.9 9.4 0.14 12.0 0.1 3.5 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kinase-like PF14531.6 PSC69607.1 - 0.0022 17.3 0.2 0.014 14.7 0.0 2.3 2 1 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 PSC69607.1 - 0.0064 15.6 0.0 0.013 14.6 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 Haspin_kinase PF12330.8 PSC69607.1 - 0.12 11.3 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain AD PF09793.9 PSC69608.1 - 4.6e-22 78.0 0.0 1.1e-21 76.8 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain PPR_long PF17177.4 PSC69608.1 - 7.1e-17 61.5 7.1 9.5e-06 25.1 0.1 5.1 3 1 2 5 5 5 4 Pentacotripeptide-repeat region of PRORP SAP PF02037.27 PSC69608.1 - 2.5e-06 27.1 1.7 5.7e-06 25.9 0.4 2.3 2 0 0 2 2 2 1 SAP domain PPR_2 PF13041.6 PSC69608.1 - 4e-05 23.7 0.0 0.081 13.1 0.0 3.9 3 1 1 4 4 4 1 PPR repeat family PPR PF01535.20 PSC69608.1 - 0.00017 21.6 0.0 13 6.3 0.0 5.1 5 0 0 5 5 5 2 PPR repeat PPR_3 PF13812.6 PSC69608.1 - 0.00055 20.0 0.0 0.033 14.3 0.0 2.9 2 1 1 3 3 3 1 Pentatricopeptide repeat domain Chloroa_b-bind PF00504.21 PSC69609.1 - 2.1e-49 168.2 0.0 3.5e-49 167.4 0.0 1.4 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DEAD_2 PF06733.15 PSC69609.1 - 2.5e-48 164.0 0.0 5.4e-48 162.9 0.0 1.6 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.6 PSC69609.1 - 1.4e-41 142.5 0.1 2.8e-41 141.5 0.1 1.5 1 0 0 1 1 1 1 Helicase C-terminal domain HBB PF06777.11 PSC69609.1 - 1.2e-32 113.1 0.0 2.5e-28 99.1 0.0 2.4 2 0 0 2 2 2 2 Helical and beta-bridge domain ResIII PF04851.15 PSC69609.1 - 4.1e-07 30.2 0.0 7.8e-05 22.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PSC69609.1 - 0.0065 16.3 0.2 0.17 11.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase SNF2_N PF00176.23 PSC69609.1 - 0.012 14.3 1.7 0.24 10.1 1.7 2.1 1 1 0 1 1 1 0 SNF2 family N-terminal domain PhosphMutase PF10143.9 PSC69609.1 - 0.031 14.1 0.1 6.3 6.6 0.0 2.4 2 0 0 2 2 2 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase AAA_19 PF13245.6 PSC69609.1 - 0.12 12.7 0.0 0.7 10.2 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 PSC69609.1 - 0.23 10.7 0.0 9.1 5.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) RasGAP_C PF03836.15 PSC69610.1 - 0.13 12.4 3.8 1.3 9.2 0.2 3.1 3 0 0 3 3 3 0 RasGAP C-terminus UPF0242 PF06785.11 PSC69610.1 - 0.9 9.6 24.8 0.31 11.1 3.3 4.5 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus MOZ_SAS PF01853.18 PSC69611.1 - 1.9e-82 275.3 0.2 2.8e-82 274.7 0.2 1.3 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 PSC69611.1 - 5.1e-20 70.8 2.1 1.2e-19 69.6 2.1 1.6 1 0 0 1 1 1 1 MYST family zinc finger domain rve PF00665.26 PSC69611.1 - 5.6e-18 65.3 0.0 1.1e-17 64.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Tudor-knot PF11717.8 PSC69611.1 - 9.8e-17 60.6 1.2 2.7e-16 59.2 1.2 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Cyt-b5 PF00173.28 PSC69611.1 - 2e-05 24.6 0.0 5.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Metallophos PF00149.28 PSC69611.1 - 0.0004 21.0 0.0 0.0027 18.2 0.0 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Acetyltransf_7 PF13508.7 PSC69611.1 - 0.018 15.5 0.0 0.05 14.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain rve_3 PF13683.6 PSC69611.1 - 0.038 13.8 0.0 0.092 12.5 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Chromo PF00385.24 PSC69611.1 - 0.047 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain Tfb2 PF03849.14 PSC69612.1 - 1.1e-79 268.0 0.0 1.4e-79 267.7 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 PSC69612.1 - 4.2e-18 65.5 0.0 7.3e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 PSC69612.1 - 0.00046 20.3 0.1 0.0009 19.4 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Tfb2 PF03849.14 PSC69613.1 - 4.8e-80 269.2 0.0 6.1e-80 268.9 0.0 1.1 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 PSC69613.1 - 4.2e-18 65.5 0.0 7.2e-18 64.8 0.0 1.4 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 PSC69613.1 - 0.00043 20.4 0.1 0.0009 19.4 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Mito_carr PF00153.27 PSC69614.1 - 1.6e-27 95.3 5.9 6.3e-17 61.3 0.0 4.2 3 1 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.22 PSC69615.1 - 1.1e-50 171.4 0.0 1.5e-50 171.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PSC69615.1 - 1.4e-30 105.9 0.0 2.3e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PSC69615.1 - 5.2e-11 42.3 0.0 7.7e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RNA_helicase PF00910.22 PSC69615.1 - 1.1e-05 25.7 0.0 3.1e-05 24.3 0.0 1.7 1 1 0 1 1 1 1 RNA helicase MMR_HSR1 PF01926.23 PSC69615.1 - 0.0002 21.4 0.0 0.00038 20.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Pox_A32 PF04665.12 PSC69615.1 - 0.021 14.3 0.0 0.04 13.4 0.0 1.4 1 0 0 1 1 1 0 Poxvirus A32 protein G-alpha PF00503.20 PSC69615.1 - 0.039 13.1 1.5 2.2 7.4 0.1 2.7 2 1 1 3 3 3 0 G-protein alpha subunit AAA_7 PF12775.7 PSC69615.1 - 0.049 13.1 0.0 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region RsgA_GTPase PF03193.16 PSC69615.1 - 0.051 13.5 0.0 7.1 6.5 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 PSC69615.1 - 0.055 13.2 0.1 0.093 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 PSC69615.1 - 0.059 13.4 0.0 0.17 11.9 0.0 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Gtr1_RagA PF04670.12 PSC69615.1 - 0.099 12.0 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_33 PF13671.6 PSC69615.1 - 0.12 12.5 0.1 0.24 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain ArgoMid PF16487.5 PSC69615.1 - 0.12 12.6 0.2 0.36 11.1 0.0 1.9 2 0 0 2 2 2 0 Mid domain of argonaute ATPase PF06745.13 PSC69615.1 - 0.13 11.6 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 KaiC ABC_tran PF00005.27 PSC69615.1 - 0.15 12.5 0.0 0.77 10.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter ATP_bind_1 PF03029.17 PSC69615.1 - 0.16 11.7 0.1 11 5.7 0.0 2.2 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 PSC69615.1 - 0.18 12.1 0.0 0.31 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RRF PF01765.19 PSC69617.1 - 2.8e-51 173.7 0.5 3.2e-51 173.5 0.5 1.0 1 0 0 1 1 1 1 Ribosome recycling factor IF-2B PF01008.17 PSC69617.1 - 0.028 13.7 0.8 0.041 13.1 0.8 1.2 1 0 0 1 1 1 0 Initiation factor 2 subunit family DUF1319 PF07028.11 PSC69617.1 - 0.043 14.0 0.2 0.069 13.4 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1319) Complex1_51K PF01512.17 PSC69617.1 - 0.06 13.2 0.9 0.096 12.6 0.9 1.2 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase 51 Kd subunit EF-hand_1 PF00036.32 PSC69619.1 - 5e-12 44.5 0.0 0.00016 20.9 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 PSC69619.1 - 2.2e-11 42.7 0.0 0.00014 21.2 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 PSC69619.1 - 2.4e-11 43.9 0.0 4.7e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PSC69619.1 - 2e-10 39.7 0.0 0.00015 21.4 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 PSC69619.1 - 2.1e-05 24.3 0.0 0.012 15.4 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair p25-alpha PF05517.12 PSC69619.1 - 0.0056 16.9 0.0 0.014 15.6 0.0 1.6 2 0 0 2 2 2 1 p25-alpha Misat_Tub_SegII PF10644.9 PSC69620.1 - 5e-30 104.2 0.0 7.4e-30 103.7 0.0 1.2 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 PSC69620.1 - 3.2e-19 69.3 0.0 2.6e-18 66.3 0.0 2.0 1 1 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 PSC69620.1 - 0.0057 16.9 0.0 0.93 9.6 0.0 2.5 2 0 0 2 2 2 2 Tubulin/FtsZ family, GTPase domain TP_methylase PF00590.20 PSC69621.1 - 2.8e-27 96.1 0.8 3.8e-27 95.6 0.8 1.2 1 0 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases PucR PF07905.11 PSC69621.1 - 0.031 14.5 0.1 0.069 13.4 0.1 1.5 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family ALG11_N PF15924.5 PSC69622.1 - 3.2e-75 252.8 0.0 4.3e-75 252.3 0.0 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 PSC69622.1 - 5.4e-19 68.4 0.0 1.1e-18 67.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PSC69622.1 - 1.8e-09 38.1 1.2 1.1e-08 35.6 0.2 2.6 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 PSC69622.1 - 0.067 13.2 1.6 0.18 11.8 1.6 1.8 1 1 0 1 1 1 0 Glycosyltransferase Family 4 RVT_2 PF07727.14 PSC69623.1 - 3.6e-73 246.2 0.0 4.6e-73 245.8 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Crr6 PF08847.11 PSC69623.1 - 0.064 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Chlororespiratory reduction 6 Amidase PF01425.21 PSC69624.1 - 1.1e-69 235.5 0.0 1.5e-69 235.1 0.0 1.1 1 0 0 1 1 1 1 Amidase DUF2325 PF10087.9 PSC69624.1 - 0.092 12.9 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2325) zf-met2 PF12907.7 PSC69625.1 - 2.9e-14 52.9 5.0 4.3e-14 52.4 5.0 1.3 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 PSC69625.1 - 5.4e-05 24.0 10.7 0.00011 23.0 10.7 1.5 1 0 0 1 1 1 1 4F5 protein family Dynamin_N PF00350.23 PSC69626.1 - 1.3e-15 57.9 0.5 1.9e-13 50.8 0.0 3.6 3 1 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 PSC69626.1 - 4.5e-05 23.5 0.0 0.00027 21.0 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase TFIIA PF03153.13 PSC69626.1 - 0.001 19.1 27.4 0.001 19.1 27.4 2.8 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit RsgA_GTPase PF03193.16 PSC69626.1 - 0.0098 15.8 0.0 0.048 13.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 PSC69626.1 - 0.027 15.0 0.0 0.027 15.0 0.0 2.7 3 0 0 3 3 3 0 ABC transporter IIGP PF05049.13 PSC69626.1 - 0.061 12.4 0.0 0.12 11.4 0.0 1.4 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_22 PF13401.6 PSC69626.1 - 0.83 9.9 4.6 2.6 8.3 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 PSC69626.1 - 1.1 9.6 0.0 1.1 9.6 0.0 5.4 4 2 1 5 5 5 0 AAA ATPase domain CT_A_B PF02626.15 PSC69627.1 - 4.8e-92 308.3 0.6 8e-92 307.6 0.1 1.7 2 0 0 2 2 2 1 Carboxyltransferase domain, subdomain A and B CPSase_L_D2 PF02786.17 PSC69627.1 - 1.8e-62 210.6 0.0 3.4e-62 209.7 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CT_C_D PF02682.16 PSC69627.1 - 8.8e-47 159.5 0.0 2.1e-46 158.2 0.0 1.7 2 0 0 2 2 2 1 Carboxyltransferase domain, subdomain C and D Biotin_carb_N PF00289.22 PSC69627.1 - 5.6e-39 133.1 0.0 1.3e-38 131.9 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 PSC69627.1 - 3.4e-31 107.6 0.0 9.9e-31 106.0 0.0 1.9 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 PSC69627.1 - 2.8e-14 52.7 2.1 2.8e-14 52.7 2.1 1.9 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 PSC69627.1 - 5.6e-10 39.1 0.0 1.4e-09 37.8 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 PSC69627.1 - 5.3e-09 35.8 3.7 0.00019 21.2 0.1 3.5 2 1 1 3 3 3 2 Biotin-lipoyl like HlyD_D23 PF16576.5 PSC69627.1 - 0.00011 21.6 1.2 0.26 10.5 0.0 2.7 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 PSC69627.1 - 0.00039 21.1 0.4 3.9 8.2 0.0 3.7 3 0 0 3 3 3 2 HlyD family secretion protein GCV_H PF01597.19 PSC69627.1 - 0.0053 16.6 0.3 0.011 15.6 0.3 1.5 1 0 0 1 1 1 1 Glycine cleavage H-protein ATP-grasp_3 PF02655.14 PSC69627.1 - 0.014 15.5 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ANAPC5 PF12862.7 PSC69628.1 - 2.3e-22 78.9 2.8 2.4e-22 78.8 0.1 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 5 TRAPPC9-Trs120 PF08626.11 PSC69628.1 - 0.0043 14.5 0.4 0.0061 14.0 0.4 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit TPR_12 PF13424.6 PSC69628.1 - 0.0085 16.4 8.5 0.0085 16.4 8.5 6.2 4 1 1 5 5 5 2 Tetratricopeptide repeat DUF4677 PF15726.5 PSC69628.1 - 0.018 15.2 0.3 0.047 13.9 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) TPR_8 PF13181.6 PSC69628.1 - 0.064 13.5 3.9 0.27 11.5 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 PSC69628.1 - 3.7 7.9 11.2 2.1 8.6 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat SSF PF00474.17 PSC69629.1 - 6.9e-22 77.9 35.0 9.9e-22 77.3 35.0 1.2 1 0 0 1 1 1 1 Sodium:solute symporter family Acetyltransf_1 PF00583.25 PSC69630.1 - 8.9e-13 48.5 0.1 1.4e-12 47.9 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PSC69630.1 - 5.4e-08 33.2 0.1 9.6e-08 32.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PSC69630.1 - 5.6e-08 32.8 0.1 1e-07 31.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC69630.1 - 7.2e-08 32.3 0.1 1.2e-07 31.5 0.1 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.6 PSC69630.1 - 0.00098 18.8 0.0 0.0018 17.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PSC69630.1 - 0.013 16.2 0.0 0.021 15.5 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain HTH_6 PF01418.17 PSC69630.1 - 0.02 14.8 0.3 0.044 13.8 0.0 1.6 2 0 0 2 2 2 0 Helix-turn-helix domain, rpiR family Ribosomal_60s PF00428.19 PSC69630.1 - 0.3 11.7 4.4 0.62 10.7 4.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein AMP-binding PF00501.28 PSC69631.1 - 0.013 14.1 0.1 1.1 7.7 0.0 2.2 2 0 0 2 2 2 0 AMP-binding enzyme Phage_tail_APC PF16778.5 PSC69631.1 - 0.044 13.6 0.0 15 5.5 0.0 2.6 2 0 0 2 2 2 0 Phage tail assembly chaperone protein AMP-binding PF00501.28 PSC69632.1 - 0.034 12.8 0.1 1.9 7.0 0.0 2.3 2 0 0 2 2 2 0 AMP-binding enzyme Phage_tail_APC PF16778.5 PSC69632.1 - 0.048 13.5 0.4 23 5.0 0.0 3.2 3 0 0 3 3 3 0 Phage tail assembly chaperone protein PPR_2 PF13041.6 PSC69633.1 - 1.6e-33 114.6 0.0 1.2e-10 41.4 0.0 8.3 5 3 3 8 8 8 7 PPR repeat family PPR_3 PF13812.6 PSC69633.1 - 2e-21 75.8 0.0 3.4e-07 30.2 0.0 6.6 6 1 1 7 7 7 4 Pentatricopeptide repeat domain PPR PF01535.20 PSC69633.1 - 7.8e-19 66.5 1.1 0.00034 20.7 0.0 8.7 10 0 0 10 10 10 3 PPR repeat PPR_long PF17177.4 PSC69633.1 - 1.3e-12 47.5 1.7 0.00034 20.0 0.2 4.8 3 1 3 6 6 6 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 PSC69633.1 - 3.7e-12 45.7 0.0 1.7 8.4 0.0 8.3 9 0 0 9 9 9 3 PPR repeat ELYS PF13934.6 PSC69633.1 - 0.0032 17.5 0.2 0.0088 16.0 0.2 1.7 1 1 0 1 1 1 1 Nuclear pore complex assembly Ufm1 PF03671.14 PSC69633.1 - 0.055 13.6 0.2 10 6.3 0.1 2.6 2 0 0 2 2 2 0 Ubiquitin fold modifier 1 protein ArgJ PF01960.18 PSC69634.1 - 2.4e-139 464.3 7.8 2.8e-139 464.1 7.8 1.0 1 0 0 1 1 1 1 ArgJ family HMMR_N PF15905.5 PSC69635.1 - 0.57 9.6 38.0 0.84 9.0 8.2 3.1 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Fez1 PF06818.15 PSC69635.1 - 1.6 9.2 49.9 1.4 9.4 5.6 3.2 1 1 2 3 3 3 0 Fez1 Podoplanin PF05808.11 PSC69635.1 - 2.4 8.2 4.4 2.1 8.4 1.6 2.3 1 1 1 2 2 2 0 Podoplanin RRM_1 PF00076.22 PSC69636.1 - 2.4e-15 56.1 0.0 3.5e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 PSC69636.1 - 1.1e-08 34.7 2.1 2.1e-08 33.9 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 PSC69636.1 - 0.018 14.9 0.3 0.029 14.2 0.3 1.4 1 0 0 1 1 1 0 Zinc knuckle RRM_7 PF16367.5 PSC69636.1 - 0.035 14.2 0.0 0.059 13.5 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif zf-CCHC_4 PF14392.6 PSC69636.1 - 0.11 12.3 0.5 0.16 11.7 0.5 1.2 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 PSC69636.1 - 0.29 11.0 2.9 0.53 10.2 2.9 1.4 1 0 0 1 1 1 0 Zinc knuckle RRM_1 PF00076.22 PSC69637.1 - 2.2e-15 56.2 0.0 3.2e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 PSC69637.1 - 1.1e-08 34.8 2.1 2e-08 34.0 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 PSC69637.1 - 0.017 14.9 0.3 0.027 14.3 0.3 1.3 1 0 0 1 1 1 0 Zinc knuckle RRM_7 PF16367.5 PSC69637.1 - 0.032 14.3 0.0 0.055 13.6 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif zf-CCHC_4 PF14392.6 PSC69637.1 - 0.1 12.4 0.5 0.15 11.8 0.5 1.2 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_6 PF15288.6 PSC69637.1 - 0.27 11.1 2.9 0.5 10.3 2.9 1.4 1 0 0 1 1 1 0 Zinc knuckle YabA PF06156.13 PSC69638.1 - 0.017 15.7 6.6 0.59 10.8 0.2 2.5 2 0 0 2 2 2 0 Initiation control protein YabA BLOC1_2 PF10046.9 PSC69638.1 - 0.053 13.8 3.7 0.14 12.5 3.7 1.6 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TEX13 PF15186.6 PSC69638.1 - 0.066 12.9 6.0 0.15 11.7 6.0 1.6 1 0 0 1 1 1 0 Testis-expressed sequence 13 protein family HAUS6_N PF14661.6 PSC69638.1 - 0.19 11.3 6.1 0.42 10.1 6.1 1.5 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus ArsC PF03960.15 PSC69638.1 - 0.26 11.3 0.6 2.9 8.0 0.3 2.6 2 1 0 2 2 2 0 ArsC family Plasmid_RAQPRD PF09686.10 PSC69638.1 - 0.33 11.2 9.4 0.078 13.2 5.4 2.2 2 0 0 2 2 2 0 Plasmid protein of unknown function (Plasmid_RAQPRD) FapA PF03961.13 PSC69638.1 - 0.33 9.5 0.3 0.54 8.8 0.3 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A CHD5 PF04420.14 PSC69638.1 - 0.38 10.6 6.5 0.88 9.4 6.5 1.5 1 0 0 1 1 1 0 CHD5-like protein KASH_CCD PF14662.6 PSC69638.1 - 0.42 10.4 11.8 2.4 7.9 5.9 2.3 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 PSC69638.1 - 0.67 9.3 13.3 0.079 12.3 7.4 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Exonuc_VII_L PF02601.15 PSC69638.1 - 1.1 8.7 7.6 2 7.9 7.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit APG6_N PF17675.1 PSC69638.1 - 1.6 9.3 18.0 1.6 9.2 9.6 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region Phage_GPO PF05929.11 PSC69638.1 - 2.1 7.9 8.3 2.2 7.8 7.4 1.4 1 1 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase ZapB PF06005.12 PSC69638.1 - 3.2 8.3 22.1 0.79 10.2 7.2 3.4 1 1 2 3 3 3 0 Cell division protein ZapB PRKG1_interact PF15898.5 PSC69638.1 - 4.9 8.1 12.5 2.2 9.3 7.0 2.5 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF3950 PF13132.6 PSC69639.1 - 0.24 11.2 2.6 0.45 10.3 2.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3950) TPR_MLP1_2 PF07926.12 PSC69640.1 - 7.3e-16 58.4 20.9 7.3e-16 58.4 20.9 19.0 8 4 10 20 20 20 5 TPR/MLP1/MLP2-like protein DGOK PF05035.12 PSC69641.1 - 0.042 12.7 0.4 0.46 9.3 0.0 2.0 2 0 0 2 2 2 0 2-keto-3-deoxy-galactonokinase SNF2_N PF00176.23 PSC69642.1 - 7.5e-61 205.8 0.9 1.3e-60 205.0 0.7 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC69642.1 - 8.3e-16 58.3 0.0 1.9e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC69642.1 - 3.3e-08 33.7 0.0 6e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PSC69642.1 - 2e-05 24.5 0.0 3.3e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Agenet PF05641.12 PSC69642.1 - 5.5e-05 23.5 0.5 0.0033 17.9 0.0 2.8 2 0 0 2 2 2 1 Agenet domain PHD PF00628.29 PSC69642.1 - 6.4e-05 22.8 16.1 7.5e-05 22.5 3.8 2.5 2 0 0 2 2 2 1 PHD-finger HDA2-3 PF11496.8 PSC69642.1 - 6.8e-05 22.2 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 PHD_4 PF16866.5 PSC69642.1 - 0.0038 17.3 2.4 0.015 15.4 2.4 2.1 1 1 0 1 1 1 1 PHD-finger TFIIA PF03153.13 PSC69642.1 - 0.1 12.6 6.6 0.18 11.8 6.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Metallothio_Pro PF02069.16 PSC69642.1 - 0.17 12.2 6.8 0.42 10.9 6.8 1.6 1 0 0 1 1 1 0 Prokaryotic metallothionein zf-AN1 PF01428.16 PSC69642.1 - 1.9 8.7 8.2 0.42 10.8 3.5 2.2 2 0 0 2 2 2 0 AN1-like Zinc finger Zf_RING PF16744.5 PSC69642.1 - 1.9 8.7 9.5 0.32 11.2 5.0 2.1 1 1 1 2 2 1 0 KIAA1045 RING finger Suf PF05843.14 PSC69643.1 - 0.82 9.6 10.1 1.4 8.9 10.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM27 PF15832.5 PSC69643.1 - 1 10.0 11.8 4.3 8.0 6.7 2.8 2 0 0 2 2 2 0 FAM27 D and E protein family Lin-8 PF03353.15 PSC69643.1 - 1.8 8.1 9.1 2.8 7.4 9.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 PSC69643.1 - 3.6 6.3 5.7 5.2 5.7 5.7 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 PSC69643.1 - 4.1 7.3 20.1 6.7 6.6 20.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PSK PF06404.12 PSC69643.1 - 6.2 7.9 10.9 38 5.4 6.1 3.3 3 0 0 3 3 3 0 Phytosulfokine precursor protein (PSK) Suf PF05843.14 PSC69644.1 - 0.75 9.7 10.1 1.3 9.0 10.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) FAM27 PF15832.5 PSC69644.1 - 0.95 10.0 11.8 3.9 8.1 6.8 2.6 2 0 0 2 2 2 0 FAM27 D and E protein family Lin-8 PF03353.15 PSC69644.1 - 1.6 8.2 9.1 2.5 7.6 9.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Presenilin PF01080.17 PSC69644.1 - 3.2 6.4 5.7 4.7 5.9 5.7 1.1 1 0 0 1 1 1 0 Presenilin PSK PF06404.12 PSC69644.1 - 3.5 8.7 10.4 35 5.5 6.1 3.4 3 0 0 3 3 3 0 Phytosulfokine precursor protein (PSK) TFIIA PF03153.13 PSC69644.1 - 3.7 7.4 20.1 6 6.7 20.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3959 PF13105.6 PSC69645.1 - 0.052 13.0 0.1 0.052 13.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3959) D5_N PF08706.11 PSC69645.1 - 0.087 13.1 1.3 0.2 11.9 1.3 1.6 1 0 0 1 1 1 0 D5 N terminal like PWI PF01480.17 PSC69646.1 - 1.7e-10 41.0 0.2 2.2e-09 37.5 0.1 2.2 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.22 PSC69646.1 - 6.7e-09 35.4 0.0 1.2e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ig_5 PF16681.5 PSC69646.1 - 0.045 14.2 0.1 0.087 13.2 0.1 1.4 1 0 0 1 1 1 0 Ig-like domain on T-cell surface glycoprotein CD3 epsilon chain Pkinase PF00069.25 PSC69648.1 - 4.8e-46 157.3 0.0 2.1e-32 112.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC69648.1 - 3.9e-19 69.0 0.0 7e-12 45.2 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase tRNA-synt_His PF13393.6 PSC69648.1 - 1.3e-13 50.9 0.2 4.8e-12 45.8 0.2 2.6 1 1 0 1 1 1 1 Histidyl-tRNA synthetase RWD PF05773.22 PSC69648.1 - 6.9e-10 39.2 0.0 1.1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain HGTP_anticodon2 PF12745.7 PSC69648.1 - 1e-09 38.3 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs HGTP_anticodon PF03129.20 PSC69648.1 - 4.7e-09 36.3 0.0 8.3e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain APH PF01636.23 PSC69648.1 - 0.00044 20.3 1.7 0.0023 17.9 0.0 3.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PSC69648.1 - 0.00055 19.3 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PSC69648.1 - 0.078 12.3 0.0 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 PSC69649.1 - 4.8e-46 157.3 0.0 2.1e-32 112.5 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC69649.1 - 3.9e-19 69.0 0.0 7e-12 45.2 0.0 3.1 2 1 0 2 2 2 2 Protein tyrosine kinase tRNA-synt_His PF13393.6 PSC69649.1 - 1.3e-13 50.9 0.2 4.8e-12 45.8 0.2 2.6 1 1 0 1 1 1 1 Histidyl-tRNA synthetase RWD PF05773.22 PSC69649.1 - 6.9e-10 39.2 0.0 1.1e-09 38.6 0.0 1.3 1 0 0 1 1 1 1 RWD domain HGTP_anticodon2 PF12745.7 PSC69649.1 - 1e-09 38.3 0.0 1.7e-09 37.6 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs HGTP_anticodon PF03129.20 PSC69649.1 - 4.7e-09 36.3 0.0 8.3e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon binding domain APH PF01636.23 PSC69649.1 - 0.00045 20.2 1.7 0.0023 17.9 0.0 3.0 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PSC69649.1 - 0.00055 19.3 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PSC69649.1 - 0.078 12.3 0.0 0.29 10.5 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family C5-epim_C PF06662.13 PSC69650.1 - 0.024 14.2 0.4 0.046 13.2 0.4 1.4 1 0 0 1 1 1 0 D-glucuronyl C5-epimerase C-terminus R3H-assoc PF13902.6 PSC69651.1 - 2.5e-12 47.3 0.8 3.7e-12 46.8 0.8 1.2 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.22 PSC69651.1 - 0.0002 21.3 0.0 0.0003 20.7 0.0 1.3 1 0 0 1 1 1 1 R3H domain ORC6 PF05460.13 PSC69652.1 - 2.7e-05 23.6 0.0 0.00016 21.1 0.0 2.0 1 1 1 2 2 2 1 Origin recognition complex subunit 6 (ORC6) zf-RING_2 PF13639.6 PSC69653.1 - 1.5e-12 47.7 8.4 2.4e-12 47.0 8.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PSC69653.1 - 2.8e-09 36.6 4.5 6.4e-09 35.4 4.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PSC69653.1 - 3e-07 30.2 7.5 5.5e-07 29.3 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PSC69653.1 - 9.7e-07 29.0 10.5 9.7e-07 29.0 10.5 2.1 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PSC69653.1 - 1.1e-06 28.3 6.5 1.9e-06 27.6 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC69653.1 - 1.4e-05 25.0 6.8 2.9e-05 24.0 6.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 PSC69653.1 - 4.8e-05 23.3 2.7 8.8e-05 22.5 2.7 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 PSC69653.1 - 0.00015 21.6 5.9 0.00024 20.9 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PSC69653.1 - 0.00022 20.8 4.4 0.0004 20.0 4.4 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_UBOX PF13445.6 PSC69653.1 - 0.00089 19.2 1.8 0.00089 19.2 1.8 2.5 3 0 0 3 3 2 1 RING-type zinc-finger DUF2076 PF09849.9 PSC69653.1 - 0.0021 18.1 2.8 0.0021 18.1 2.8 2.9 2 1 1 3 3 2 1 Uncharacterized protein conserved in bacteria (DUF2076) DUF853 PF05872.12 PSC69653.1 - 0.017 13.8 1.5 0.022 13.4 1.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Prok-RING_4 PF14447.6 PSC69653.1 - 0.02 14.7 6.9 0.047 13.5 7.0 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.7 PSC69653.1 - 0.024 14.7 5.8 0.062 13.4 5.8 1.7 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 PSC69653.1 - 0.061 13.5 0.6 0.061 13.5 0.6 1.9 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 PSC69653.1 - 0.099 12.5 1.3 0.17 11.7 1.3 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3H2C3 PF17122.5 PSC69653.1 - 0.53 10.4 3.6 1.3 9.1 3.6 1.7 1 1 0 1 1 1 0 Zinc-finger zf-RING_4 PF14570.6 PSC69653.1 - 1.3 8.9 7.9 2.6 7.9 7.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain FANCL_C PF11793.8 PSC69653.1 - 7 6.9 8.2 32 4.8 8.2 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain LBR_tudor PF09465.10 PSC69654.1 - 3e-12 46.1 5.4 7.6e-05 22.4 0.0 4.1 4 0 0 4 4 4 3 Lamin-B receptor of TUDOR domain TUDOR_5 PF18359.1 PSC69654.1 - 7.6e-08 31.9 3.0 0.0018 17.9 0.1 4.0 5 0 0 5 5 5 3 Histone methyltransferase Tudor domain 1 53-BP1_Tudor PF09038.10 PSC69654.1 - 5.3e-06 26.4 4.0 0.15 12.1 0.2 4.0 4 0 0 4 4 4 2 Tumour suppressor p53-binding protein-1 Tudor Agenet PF05641.12 PSC69654.1 - 1.6e-05 25.3 7.0 0.43 11.1 0.3 4.8 5 0 0 5 5 5 3 Agenet domain Ribosomal_L37 PF08561.10 PSC69655.1 - 2.5e-09 37.7 5.7 1.9e-07 31.6 0.9 2.1 1 1 1 2 2 2 2 Mitochondrial ribosomal protein L37 Pkinase_Tyr PF07714.17 PSC69656.1 - 4.4e-45 154.0 0.0 1.9e-37 129.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PSC69656.1 - 2.5e-40 138.5 0.0 1.6e-33 116.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 PSC69656.1 - 0.036 13.4 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PSC69656.1 - 0.06 13.3 0.0 0.06 13.3 0.0 1.9 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF4381 PF14316.6 PSC69656.1 - 0.1 12.8 5.5 0.25 11.6 5.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) SAP130_C PF16014.5 PSC69657.1 - 0.35 9.9 16.0 0.43 9.6 16.0 1.1 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus TFIIA PF03153.13 PSC69657.1 - 5.6 6.9 13.1 7.1 6.5 13.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Inj_translocase PF16928.5 PSC69657.1 - 9.3 5.6 10.0 0.4 10.1 3.4 1.8 2 0 0 2 2 2 0 DNA/protein translocase of phage P22 injectosome ABC1 PF03109.16 PSC69658.1 - 3.4e-26 91.7 0.0 9.4e-26 90.3 0.0 1.8 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 PSC69658.1 - 0.00056 19.9 3.9 0.00056 19.9 3.9 4.1 3 2 0 3 3 3 1 Phosphotransferase enzyme family Pkinase PF00069.25 PSC69658.1 - 0.044 13.1 0.0 2.5 7.4 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain Allexi_40kDa PF05549.11 PSC69658.1 - 0.065 12.7 0.0 0.1 12.1 0.0 1.2 1 0 0 1 1 1 0 Allexivirus 40kDa protein Chloroa_b-bind PF00504.21 PSC69659.1 - 1.1e-51 175.5 0.1 1.4e-51 175.3 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein ABC_membrane PF00664.23 PSC69661.1 - 2.7e-34 119.1 5.3 4.3e-34 118.4 5.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PSC69661.1 - 1.2e-29 103.5 0.0 1.2e-29 103.5 0.0 2.3 2 1 0 2 2 1 1 ABC transporter WD40 PF00400.32 PSC69661.1 - 8.9e-29 99.1 4.5 1.4e-05 25.7 0.0 7.1 8 0 0 8 8 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC69661.1 - 4e-10 39.9 0.0 9.3e-05 22.7 0.0 4.3 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Usp PF00582.26 PSC69661.1 - 9.7e-10 39.1 1.1 9.7e-10 39.1 1.1 5.0 4 2 1 5 5 3 1 Universal stress protein family LisH_TPL PF17814.1 PSC69661.1 - 2.4e-09 36.7 0.5 4.5e-09 35.8 0.5 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain SMC_N PF02463.19 PSC69661.1 - 2.8e-08 33.5 0.7 2.1e-06 27.4 0.1 2.6 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain Ge1_WD40 PF16529.5 PSC69661.1 - 2.2e-07 30.2 1.5 0.13 11.2 0.0 4.1 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PSC69661.1 - 0.021 13.5 0.1 0.1 11.3 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 AAA_25 PF13481.6 PSC69661.1 - 0.036 13.7 0.0 0.17 11.5 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PSC69661.1 - 0.048 13.4 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 PSC69661.1 - 0.072 13.4 0.0 0.072 13.4 0.0 4.3 4 1 0 4 4 4 0 AAA domain RsgA_GTPase PF03193.16 PSC69661.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ABC_membrane PF00664.23 PSC69662.1 - 2.7e-34 119.1 5.3 4.3e-34 118.4 5.3 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PSC69662.1 - 1.2e-29 103.5 0.0 1.2e-29 103.5 0.0 2.3 2 1 0 2 2 1 1 ABC transporter WD40 PF00400.32 PSC69662.1 - 9e-29 99.1 4.5 1.4e-05 25.7 0.0 7.1 8 0 0 8 8 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC69662.1 - 4e-10 39.8 0.0 9.3e-05 22.7 0.0 4.3 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Usp PF00582.26 PSC69662.1 - 9.7e-10 39.1 1.1 9.7e-10 39.1 1.1 5.0 4 2 1 5 5 3 1 Universal stress protein family LisH_TPL PF17814.1 PSC69662.1 - 2.4e-09 36.7 0.5 4.5e-09 35.8 0.5 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain SMC_N PF02463.19 PSC69662.1 - 2.9e-08 33.4 0.7 2.1e-06 27.4 0.1 2.6 1 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain Ge1_WD40 PF16529.5 PSC69662.1 - 2.2e-07 30.2 1.5 0.13 11.2 0.0 4.1 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PSC69662.1 - 0.021 13.5 0.1 0.1 11.2 0.0 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 AAA_25 PF13481.6 PSC69662.1 - 0.036 13.7 0.0 0.17 11.5 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PSC69662.1 - 0.048 13.4 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 PSC69662.1 - 0.072 13.4 0.0 0.072 13.4 0.0 4.3 4 1 0 4 4 4 0 AAA domain RsgA_GTPase PF03193.16 PSC69662.1 - 0.11 12.4 0.0 0.25 11.2 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase ACOX PF01756.19 PSC69663.1 - 1.2e-48 165.1 0.0 1.7e-47 161.3 0.0 2.3 2 1 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 PSC69663.1 - 2.2e-29 102.5 0.0 3.6e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 PSC69663.1 - 1e-11 44.8 0.0 2.2e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 PSC69663.1 - 0.0017 19.0 0.0 0.0052 17.4 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_1 PF00441.24 PSC69663.1 - 0.0061 16.8 0.2 0.0061 16.8 0.2 2.4 2 1 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain ABC2_membrane PF01061.24 PSC69664.1 - 1.4e-40 139.0 9.2 2.1e-40 138.4 9.2 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PSC69664.1 - 9.3e-22 78.0 0.0 6.9e-21 75.2 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 PSC69664.1 - 5.1e-06 26.5 0.0 0.046 13.5 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PSC69664.1 - 2.2e-05 24.9 0.9 6.5e-05 23.4 0.2 2.1 2 1 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 PSC69664.1 - 0.00047 19.4 9.8 0.00076 18.7 9.8 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 PSC69664.1 - 0.00087 19.2 0.1 0.022 14.7 0.3 2.3 2 0 0 2 2 2 1 RsgA GTPase ABC2_membrane_2 PF12679.7 PSC69664.1 - 0.0014 18.0 6.7 0.0031 16.8 6.9 1.6 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_22 PF13401.6 PSC69664.1 - 0.0038 17.5 0.0 0.0095 16.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 PSC69664.1 - 0.0089 15.1 0.3 0.016 14.3 0.3 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.6 PSC69664.1 - 0.024 15.1 0.2 0.039 14.4 0.2 1.2 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 PSC69664.1 - 0.025 14.6 0.1 0.042 13.9 0.1 1.3 1 0 0 1 1 1 0 Dynamin family AAA_25 PF13481.6 PSC69664.1 - 0.037 13.6 0.6 0.096 12.2 0.6 1.7 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 PSC69664.1 - 0.059 12.8 0.0 0.92 8.9 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PSC69664.1 - 0.074 12.8 0.8 0.2 11.4 0.1 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 PSC69664.1 - 0.084 13.0 0.1 0.16 12.1 0.1 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA PF00004.29 PSC69664.1 - 0.14 12.6 0.1 0.92 9.9 0.1 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 PSC69664.1 - 0.19 11.9 0.8 0.38 10.9 0.1 1.8 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 PSC69664.1 - 0.67 10.0 1.7 5.9 6.9 0.2 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 PSC69664.1 - 2.3 8.5 4.1 0.91 9.7 0.8 1.9 2 0 0 2 2 2 0 AAA domain Polyketide_cyc2 PF10604.9 PSC69666.1 - 0.00051 20.3 0.1 0.00096 19.4 0.1 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport TPM_phosphatase PF04536.14 PSC69667.1 - 2e-18 66.7 0.2 3.5e-18 66.0 0.2 1.4 1 0 0 1 1 1 1 TPM domain SPT_ssu-like PF11779.8 PSC69667.1 - 3.7e-05 23.3 5.5 7.4e-05 22.3 5.5 1.4 1 0 0 1 1 1 1 Small subunit of serine palmitoyltransferase-like HTH_20 PF12840.7 PSC69667.1 - 0.067 13.3 0.1 0.19 11.8 0.1 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3687 PF12459.8 PSC69667.1 - 0.14 11.7 1.3 1.6 8.3 0.6 2.2 2 0 0 2 2 2 0 D-Ala-teichoic acid biosynthesis protein PsbQ PF05757.11 PSC69667.1 - 2.4 7.8 12.1 0.041 13.6 2.1 2.3 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) Cytochrome_CBB3 PF13442.6 PSC69669.1 - 1.3e-08 35.0 2.7 3.5e-07 30.5 2.7 2.2 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 PSC69669.1 - 0.00051 19.8 0.0 0.1 12.3 0.0 2.1 2 0 0 2 2 2 2 Cytochrome c-550 domain Cytochrom_C PF00034.21 PSC69669.1 - 0.01 17.0 0.1 0.022 15.9 0.1 1.5 1 1 0 1 1 1 0 Cytochrome c IlvGEDA_leader PF08046.11 PSC69669.1 - 0.24 10.9 0.3 0.43 10.1 0.3 1.3 1 0 0 1 1 1 0 IlvGEDA operon leader peptide MatE PF01554.18 PSC69670.1 - 7.9e-11 41.9 31.8 4.7e-09 36.1 7.9 2.7 3 0 0 3 3 3 2 MatE Oxysterol_BP PF01237.18 PSC69671.1 - 5e-44 150.7 0.0 1.8e-36 125.8 0.0 2.1 2 0 0 2 2 2 2 Oxysterol-binding protein WD40 PF00400.32 PSC69674.1 - 3.4e-22 78.3 10.1 1.1e-08 35.6 0.1 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC69674.1 - 5.4e-06 26.6 0.0 0.0049 17.1 0.0 3.9 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain AMP-binding PF00501.28 PSC69675.1 - 6.1e-65 219.5 0.0 7.8e-34 117.0 0.0 2.7 2 1 1 3 3 3 2 AMP-binding enzyme Biopterin_H PF00351.21 PSC69676.1 - 6.2e-32 110.9 0.0 8.1e-32 110.6 0.0 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase TMEM70 PF06979.12 PSC69677.1 - 1.4e-18 67.6 0.0 2.4e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Assembly, mitochondrial proton-transport ATP synth complex INSIG PF07281.12 PSC69677.1 - 8.6e-11 41.9 6.6 3.6e-10 39.9 6.2 2.2 1 1 0 1 1 1 1 Insulin-induced protein (INSIG) DUF2722 PF10846.8 PSC69677.1 - 0.00017 20.7 0.4 0.00019 20.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) CrgA PF06781.12 PSC69677.1 - 0.0046 17.0 0.5 0.013 15.5 0.1 2.0 2 0 0 2 2 2 1 Cell division protein CrgA TFIIA PF03153.13 PSC69677.1 - 0.027 14.5 10.2 0.036 14.1 10.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rot1 PF10681.9 PSC69677.1 - 0.036 13.6 0.1 0.052 13.1 0.1 1.2 1 0 0 1 1 1 0 Chaperone for protein-folding within the ER, fungal Suf PF05843.14 PSC69677.1 - 0.039 13.9 1.3 0.049 13.6 1.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Orf78 PF06024.12 PSC69677.1 - 0.26 11.6 0.3 0.45 10.9 0.3 1.3 1 0 0 1 1 1 0 Orf78 (ac78) TctB PF07331.11 PSC69677.1 - 1.9 8.8 6.6 0.64 10.3 2.2 2.2 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family FAT PF02259.23 PSC69678.1 - 1.1e-77 261.6 0.0 2e-77 260.7 0.0 1.5 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 PSC69678.1 - 3.4e-75 253.1 0.0 5.3e-75 252.5 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FRB_dom PF08771.11 PSC69678.1 - 1.4e-42 144.1 2.6 4.7e-42 142.4 2.6 2.0 1 0 0 1 1 1 1 FKBP12-rapamycin binding domain DUF3385 PF11865.8 PSC69678.1 - 5.2e-40 137.0 0.0 6.3e-39 133.5 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) Pkinase PF00069.25 PSC69678.1 - 3.2e-13 49.7 0.0 9.2e-13 48.2 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain FATC PF02260.20 PSC69678.1 - 4e-13 48.9 0.8 1.5e-12 47.1 0.8 2.1 1 0 0 1 1 1 1 FATC domain Pkinase_Tyr PF07714.17 PSC69678.1 - 2e-12 47.0 0.0 1e-11 44.6 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase HEAT PF02985.22 PSC69678.1 - 2.3e-09 36.7 24.5 0.44 10.9 0.0 11.7 11 0 0 11 11 10 2 HEAT repeat HEAT_2 PF13646.6 PSC69678.1 - 3.2e-07 30.6 1.6 5.4e-05 23.5 1.2 11.9 12 1 1 13 13 13 2 HEAT repeats LRRNT_2 PF08263.12 PSC69678.1 - 2.5e-05 24.5 0.3 0.0001 22.5 0.3 2.2 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_8 PF13855.6 PSC69678.1 - 0.00012 21.8 0.9 0.0013 18.5 0.5 2.9 3 0 0 3 3 3 1 Leucine rich repeat Adaptin_N PF01602.20 PSC69678.1 - 0.00013 20.7 0.3 0.87 8.1 0.0 4.5 3 2 1 4 4 4 2 Adaptin N terminal region Cnd1 PF12717.7 PSC69678.1 - 0.00014 22.0 0.0 0.013 15.5 0.0 3.4 3 0 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 LRR_4 PF12799.7 PSC69678.1 - 0.0019 18.6 0.0 0.21 12.1 0.0 3.6 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) Pkinase_fungal PF17667.1 PSC69678.1 - 0.015 14.1 0.0 0.026 13.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Arm PF00514.23 PSC69678.1 - 0.017 15.2 12.0 2.9 8.1 0.1 6.5 8 0 0 8 8 6 0 Armadillo/beta-catenin-like repeat UME PF08064.13 PSC69678.1 - 0.032 14.1 0.3 3 7.8 0.0 4.3 3 1 1 4 4 3 0 UME (NUC010) domain RIX1 PF08167.12 PSC69678.1 - 0.1 12.4 4.6 5.8 6.6 0.0 5.1 6 0 0 6 6 5 0 rRNA processing/ribosome biogenesis Cohesin_HEAT PF12765.7 PSC69678.1 - 0.27 11.6 4.2 0.77 10.1 0.2 3.4 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion PPP4R2 PF09184.11 PSC69679.1 - 6.1e-18 65.4 0.0 1e-17 64.7 0.0 1.4 1 0 0 1 1 1 1 PPP4R2 AIRC PF00731.20 PSC69680.1 - 5.9e-65 217.4 4.9 1.6e-64 216.0 4.9 1.8 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 PSC69680.1 - 9.3e-55 184.8 0.0 1.7e-54 184.0 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain PurK_C PF17769.1 PSC69680.1 - 1.1e-18 66.7 0.1 2.2e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain Dala_Dala_lig_C PF07478.13 PSC69680.1 - 0.00036 20.1 0.0 0.0025 17.4 0.0 2.0 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus NAD_binding_2 PF03446.15 PSC69680.1 - 0.002 18.3 0.1 0.0056 16.9 0.1 1.8 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 PSC69680.1 - 0.02 14.3 0.2 0.044 13.1 0.0 1.6 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 3HCDH_N PF02737.18 PSC69680.1 - 0.075 12.9 1.1 0.19 11.6 0.4 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ATG16 PF08614.11 PSC69681.1 - 0.00016 21.9 30.0 0.00016 21.9 30.0 5.5 1 1 4 5 5 5 2 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 PSC69681.1 - 0.0022 18.0 14.4 0.0022 18.0 14.4 5.7 2 1 5 7 7 7 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 PSC69681.1 - 0.011 16.3 18.2 0.011 16.3 18.2 7.0 2 1 5 7 7 7 0 Apg6 coiled-coil region FlaC_arch PF05377.11 PSC69681.1 - 0.41 11.1 4.2 6.5 7.2 0.1 3.7 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Fib_alpha PF08702.10 PSC69681.1 - 0.96 9.6 12.3 0.23 11.6 1.3 4.0 3 2 1 4 4 4 0 Fibrinogen alpha/beta chain family Fez1 PF06818.15 PSC69681.1 - 1.1 9.7 71.1 2.8 8.3 7.9 4.7 1 1 3 4 4 4 0 Fez1 SHE3 PF17078.5 PSC69681.1 - 3.4 7.3 14.2 0.14 11.8 1.7 3.2 2 1 1 3 3 3 0 SWI5-dependent HO expression protein 3 JIP_LZII PF16471.5 PSC69681.1 - 4.6 7.5 9.0 19 5.5 2.7 3.8 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II Spc7 PF08317.11 PSC69681.1 - 5.7 5.7 75.7 0.056 12.3 8.1 5.4 1 1 4 6 6 6 0 Spc7 kinetochore protein NPV_P10 PF05531.12 PSC69681.1 - 6.1 7.4 6.3 39 4.8 0.1 4.0 2 2 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Peptidase_S9_N PF02897.15 PSC69683.1 - 6.2e-118 394.2 0.0 8.3e-118 393.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 PSC69683.1 - 1e-59 201.6 0.3 3.7e-59 199.7 0.0 2.1 3 0 0 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 PSC69683.1 - 0.014 14.7 0.2 0.038 13.3 0.2 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 TBCA PF02970.16 PSC69684.1 - 3.2e-23 81.8 2.2 3.9e-23 81.6 2.2 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor A Val_tRNA-synt_C PF10458.9 PSC69684.1 - 0.002 18.4 1.4 1.8 8.9 0.0 2.7 2 1 0 2 2 2 2 Valyl tRNA synthetase tRNA binding arm WXG100 PF06013.12 PSC69684.1 - 0.025 14.8 0.7 0.58 10.4 0.1 2.1 2 0 0 2 2 2 0 Proteins of 100 residues with WXG DUF4795 PF16043.5 PSC69684.1 - 0.035 13.7 1.3 0.044 13.4 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) T7SS_ESX_EspC PF10824.8 PSC69684.1 - 0.072 13.6 1.0 0.12 12.8 1.0 1.4 1 1 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm DUF948 PF06103.11 PSC69684.1 - 0.09 13.0 0.1 0.27 11.5 0.0 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Spc7 PF08317.11 PSC69684.1 - 0.19 10.6 4.0 0.2 10.5 0.5 1.6 1 1 0 1 1 1 0 Spc7 kinetochore protein Myelin_PLP PF01275.19 PSC69685.1 - 0.0014 18.6 5.0 0.0014 18.6 5.0 2.2 2 1 1 3 3 3 1 Myelin proteolipid protein (PLP or lipophilin) DUF1195 PF06708.11 PSC69685.1 - 0.51 10.1 1.7 0.96 9.2 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) Myelin_PLP PF01275.19 PSC69686.1 - 0.0019 18.1 5.5 0.0019 18.1 5.5 2.2 2 1 1 3 3 3 1 Myelin proteolipid protein (PLP or lipophilin) DUF1195 PF06708.11 PSC69686.1 - 0.44 10.3 1.8 0.83 9.4 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1195) adh_short_C2 PF13561.6 PSC69687.1 - 1.2e-62 211.6 1.7 1.4e-62 211.3 1.7 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PSC69687.1 - 4e-49 166.7 1.2 4.8e-49 166.5 1.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PSC69687.1 - 3.8e-11 43.2 0.4 5.5e-11 42.7 0.4 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PSC69687.1 - 0.002 17.6 0.1 0.013 15.0 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Glyco_trans_4_4 PF13579.6 PSC69687.1 - 0.041 14.3 0.4 0.38 11.2 0.1 2.1 2 0 0 2 2 2 0 Glycosyl transferase 4-like domain WD40 PF00400.32 PSC69688.1 - 2.9e-12 46.9 2.1 0.00028 21.6 0.1 4.1 4 0 0 4 4 4 3 WD domain, G-beta repeat HSP20 PF00011.21 PSC69688.1 - 0.014 15.5 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 Hsp20/alpha crystallin family ubiquitin PF00240.23 PSC69689.1 - 8e-07 28.7 0.2 2.1e-06 27.4 0.2 1.6 1 1 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 PSC69689.1 - 6.6e-06 26.5 0.1 3.5e-05 24.2 0.1 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 PSC69689.1 - 0.015 15.1 0.2 0.047 13.5 0.2 1.7 1 1 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Helicase_C PF00271.31 PSC69690.1 - 1.2e-18 67.5 0.0 1.8e-15 57.2 0.0 2.4 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 PSC69690.1 - 1.2e-17 64.2 0.0 2.3e-17 63.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 PSC69690.1 - 1.6e-09 38.3 0.0 1.6e-09 38.3 0.0 2.3 2 0 0 2 2 2 1 RecQ zinc-binding Med26 PF08711.11 PSC69690.1 - 7.7e-07 29.0 0.0 4.1e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 TFIIS helical bundle-like domain ResIII PF04851.15 PSC69690.1 - 0.00069 19.7 0.0 0.0013 18.8 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF2722 PF10846.8 PSC69690.1 - 0.026 13.5 2.7 0.041 12.8 2.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) ATP-synt_Z PF16594.5 PSC69690.1 - 0.099 12.1 0.6 0.51 9.9 0.0 2.4 2 0 0 2 2 2 0 Putative AtpZ or ATP-synthase-associated DUF4834 PF16118.5 PSC69690.1 - 0.98 10.4 3.0 2.4 9.2 3.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) ANAPC_CDC26 PF10471.9 PSC69690.1 - 1.9 9.4 14.2 0.49 11.2 8.6 2.5 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Spt20 PF12090.8 PSC69690.1 - 3.3 7.2 14.8 6.1 6.4 14.8 1.3 1 0 0 1 1 1 0 Spt20 family eIF-3_zeta PF05091.12 PSC69690.1 - 5.4 5.9 4.9 8.5 5.2 4.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) C2 PF00168.30 PSC69691.1 - 1.5e-06 28.5 0.0 1.9e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 C2 domain GST_N_4 PF17172.4 PSC69692.1 - 5.7e-10 39.8 0.1 6.8e-09 36.4 0.0 2.6 2 1 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 PSC69692.1 - 4.5e-07 29.6 0.0 1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PSC69692.1 - 0.0001 22.2 0.7 0.00041 20.3 0.1 2.4 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain HemY_N PF07219.13 PSC69692.1 - 0.22 11.7 8.4 0.16 12.2 4.6 2.9 2 0 0 2 2 2 0 HemY protein N-terminus TPR_2 PF07719.17 PSC69692.1 - 0.25 11.6 2.8 4.8 7.5 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat FbpA PF05833.11 PSC69693.1 - 3.1e-79 266.9 0.0 4e-79 266.5 0.0 1.1 1 0 0 1 1 1 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 PSC69693.1 - 4e-11 43.5 0.0 8e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-R_2 PF18297.1 PSC69693.1 - 1.5e-05 25.1 0.0 6.5e-05 23.1 0.0 2.0 2 0 0 2 2 2 1 NFACT protein RNA binding domain RPE65 PF03055.15 PSC69694.1 - 3.9e-98 329.7 0.0 4.7e-98 329.4 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein Transket_pyr PF02779.24 PSC69695.1 - 7.1e-45 152.8 0.1 1.1e-44 152.2 0.1 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 PSC69695.1 - 8.3e-43 145.2 0.1 2.2e-42 143.9 0.1 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain Glutaredoxin PF00462.24 PSC69695.1 - 0.024 14.8 0.0 0.48 10.7 0.0 2.5 2 0 0 2 2 2 0 Glutaredoxin PFOR_II PF17147.4 PSC69695.1 - 0.029 14.7 0.0 0.064 13.6 0.0 1.6 1 0 0 1 1 1 0 Pyruvate:ferredoxin oxidoreductase core domain II Pkinase_Tyr PF07714.17 PSC69696.1 - 1.3e-39 136.0 0.0 9.9e-39 133.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC69696.1 - 1.3e-28 100.2 0.0 1e-27 97.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PSC69696.1 - 7.3e-14 51.7 28.2 0.012 16.0 3.0 9.5 4 3 8 12 12 12 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC69696.1 - 5.5e-12 45.3 20.8 0.00027 20.6 0.9 7.8 4 3 4 8 8 8 5 Leucine rich repeat LRRNT_2 PF08263.12 PSC69696.1 - 4.7e-07 30.0 0.8 4.7e-07 30.0 0.8 2.4 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 PSC69696.1 - 2.9e-05 24.0 12.6 8.7 7.3 0.0 9.7 14 0 0 14 14 14 1 Leucine Rich Repeat GSAP-16 PF14959.6 PSC69696.1 - 0.081 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term Pkinase_Tyr PF07714.17 PSC69697.1 - 1.3e-39 136.0 0.0 9.9e-39 133.2 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC69697.1 - 1.2e-28 100.2 0.0 1e-27 97.2 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PSC69697.1 - 6.9e-14 51.7 28.1 0.013 16.0 3.1 9.5 4 3 8 12 12 12 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC69697.1 - 5.5e-12 45.3 20.8 0.00027 20.6 0.9 7.8 4 3 4 8 8 8 5 Leucine rich repeat LRRNT_2 PF08263.12 PSC69697.1 - 4.6e-07 30.0 0.8 4.6e-07 30.0 0.8 2.4 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 PSC69697.1 - 2.8e-05 24.1 12.6 8.7 7.3 0.0 9.7 14 0 0 14 14 14 1 Leucine Rich Repeat GSAP-16 PF14959.6 PSC69697.1 - 0.081 12.8 0.0 0.21 11.5 0.0 1.6 1 0 0 1 1 1 0 gamma-Secretase-activating protein C-term Ammonium_transp PF00909.21 PSC69698.1 - 1.4e-51 175.5 24.5 2.2e-51 174.8 24.5 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family FmdA_AmdA PF03069.15 PSC69699.1 - 1e-90 304.3 0.0 7.1e-47 160.0 0.0 2.0 1 1 1 2 2 2 2 Acetamidase/Formamidase family FmdA_AmdA PF03069.15 PSC69700.1 - 2.2e-89 299.9 0.0 3.9e-46 157.6 0.0 2.2 1 1 1 2 2 2 2 Acetamidase/Formamidase family Proteasome PF00227.26 PSC69700.1 - 1.9e-34 118.8 0.0 3.4e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit DnaJ PF00226.31 PSC69700.1 - 9e-05 22.5 0.1 0.0012 19.0 0.0 2.6 3 0 0 3 3 3 1 DnaJ domain AF-4 PF05110.13 PSC69700.1 - 0.037 12.1 3.0 0.052 11.6 3.0 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Proteasome PF00227.26 PSC69701.1 - 5.8e-35 120.5 0.0 1.1e-34 119.6 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit DnaJ PF00226.31 PSC69701.1 - 4.4e-05 23.5 0.0 0.00056 20.0 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain AF-4 PF05110.13 PSC69701.1 - 0.015 13.4 2.6 0.02 13.1 2.6 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Prp19 PF08606.11 PSC69701.1 - 4.4 7.4 6.7 2.5 8.1 2.4 2.5 3 0 0 3 3 3 0 Prp19/Pso4-like Cys_Met_Meta_PP PF01053.20 PSC69702.1 - 1.8e-129 431.6 0.0 2.3e-129 431.3 0.0 1.1 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme PP2C PF00481.21 PSC69702.1 - 7e-56 189.7 0.0 9.3e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PSC69702.1 - 0.00022 20.9 0.9 0.001 18.8 0.2 2.5 3 1 0 3 3 3 1 Protein phosphatase 2C Aminotran_5 PF00266.19 PSC69702.1 - 0.0051 15.8 0.0 0.0083 15.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V SelA PF03841.13 PSC69702.1 - 0.016 14.2 0.0 0.55 9.2 0.0 2.2 2 0 0 2 2 2 0 L-seryl-tRNA selenium transferase SpoIIE PF07228.12 PSC69702.1 - 0.029 14.3 0.3 0.16 11.9 0.2 2.1 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) Beta_elim_lyase PF01212.21 PSC69702.1 - 0.033 13.5 0.1 0.09 12.0 0.1 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 PSC69702.1 - 0.083 12.2 0.1 0.75 9.0 0.0 2.2 2 1 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family DUF2076 PF09849.9 PSC69702.1 - 0.09 12.8 0.1 0.15 12.1 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) MutS_V PF00488.21 PSC69703.1 - 5.8e-28 98.2 0.0 1e-21 77.9 0.0 2.3 2 0 0 2 2 2 2 MutS domain V Smr PF01713.21 PSC69703.1 - 2.8e-08 34.0 0.4 2.1e-07 31.2 0.4 2.7 1 0 0 1 1 1 1 Smr domain CENP-H PF05837.12 PSC69703.1 - 4.2 7.8 8.7 2.6 8.5 4.8 2.7 2 0 0 2 2 2 0 Centromere protein H (CENP-H) MutS_III PF05192.18 PSC69703.1 - 9 6.5 12.1 0.052 13.8 0.5 2.3 2 1 0 2 2 2 0 MutS domain III Bud13 PF09736.9 PSC69704.1 - 6.4e-41 140.1 2.9 6.4e-41 140.1 2.9 3.3 4 0 0 4 4 4 1 Pre-mRNA-splicing factor of RES complex Pkinase_Tyr PF07714.17 PSC69706.1 - 1e-44 152.8 0.0 5.8e-36 124.1 0.0 2.6 3 0 0 3 3 3 2 Protein tyrosine kinase Pkinase PF00069.25 PSC69706.1 - 1.6e-35 122.8 0.0 1.8e-34 119.3 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain Not1 PF04054.15 PSC69707.1 - 6.4e-126 420.2 0.0 9.5e-126 419.6 0.0 1.3 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 PSC69707.1 - 1.4e-78 263.3 2.1 1.4e-78 263.3 2.1 1.8 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 PSC69707.1 - 1.4e-61 207.0 0.0 1.1e-60 204.1 0.0 2.1 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 PSC69707.1 - 1.3e-51 174.4 3.8 3.1e-51 173.2 3.8 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 PSC69707.1 - 2.7e-34 118.4 0.0 5.2e-34 117.5 0.0 1.5 1 0 0 1 1 1 1 CCR4-NOT transcription complex subunit 1 HEAT repeat KDZ PF18758.1 PSC69708.1 - 4.9e-20 72.1 0.0 1e-19 71.0 0.0 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Hexokinase_2 PF03727.16 PSC69709.1 - 8.7e-59 198.9 0.0 1.4e-58 198.2 0.0 1.2 1 0 0 1 1 1 1 Hexokinase Hexokinase_1 PF00349.21 PSC69709.1 - 1.5e-48 165.4 0.0 2.2e-48 164.8 0.0 1.3 1 0 0 1 1 1 1 Hexokinase WW PF00397.26 PSC69709.1 - 0.036 14.1 3.7 0.073 13.2 3.7 1.5 1 0 0 1 1 1 0 WW domain RNA_pol_L_2 PF13656.6 PSC69710.1 - 1.1e-08 34.7 0.0 1.8e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain SDF PF00375.18 PSC69711.1 - 6e-101 338.3 28.2 7e-101 338.1 28.2 1.0 1 0 0 1 1 1 1 Sodium:dicarboxylate symporter family DUF4093 PF13331.6 PSC69712.1 - 1.3e-19 70.4 0.0 2.5e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4093) Toprim_4 PF13662.6 PSC69712.1 - 0.00043 20.7 0.0 0.00089 19.7 0.0 1.5 1 0 0 1 1 1 1 Toprim domain Toprim PF01751.22 PSC69712.1 - 0.00073 19.7 0.0 0.0016 18.6 0.0 1.5 1 1 0 1 1 1 1 Toprim domain Toprim_2 PF13155.6 PSC69712.1 - 0.0044 17.4 0.0 0.012 16.0 0.0 1.8 1 0 0 1 1 1 1 Toprim-like TFIIA PF03153.13 PSC69712.1 - 0.035 14.1 21.5 0.041 13.9 21.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Toprim_3 PF13362.6 PSC69712.1 - 0.05 14.0 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 Toprim domain Presenilin PF01080.17 PSC69712.1 - 0.78 8.4 3.3 0.86 8.3 3.3 1.2 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 PSC69712.1 - 5.2 5.2 18.8 6.2 5.0 18.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDP-OH_P_transf PF01066.21 PSC69713.1 - 4.6e-15 56.1 1.1 4.6e-15 56.1 1.1 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Secretin_N_2 PF07655.13 PSC69714.1 - 0.45 11.1 0.1 0.45 11.1 0.1 2.2 2 1 1 3 3 3 0 Secretin N-terminal domain Helicase_C PF00271.31 PSC69715.1 - 4.6e-14 52.7 0.0 1.6e-13 51.0 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 PSC69715.1 - 9.3e-14 51.6 0.0 1.8e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase zf-CCHC PF00098.23 PSC69715.1 - 5.9e-07 29.3 2.1 1.1e-06 28.4 2.1 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_5 PF14787.6 PSC69715.1 - 0.0038 16.9 2.1 0.0099 15.6 2.1 1.7 1 0 0 1 1 1 1 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 PSC69715.1 - 0.04 13.9 2.5 0.097 12.7 2.5 1.5 1 0 0 1 1 1 0 Zinc knuckle ResIII PF04851.15 PSC69715.1 - 0.086 12.8 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-CCHC_2 PF13696.6 PSC69715.1 - 0.19 11.6 2.3 0.35 10.7 2.3 1.4 1 0 0 1 1 1 0 Zinc knuckle SKN1 PF03935.15 PSC69716.1 - 1e-42 146.2 5.2 3.1e-32 111.6 0.6 2.2 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) PAN_4 PF14295.6 PSC69716.1 - 3.6e-06 26.8 1.1 3.6e-06 26.8 1.1 2.5 3 0 0 3 3 3 1 PAN domain Glyco_hydro_16 PF00722.21 PSC69716.1 - 2.1e-05 24.1 0.2 4.4e-05 23.0 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PAN_1 PF00024.26 PSC69716.1 - 6.3e-05 22.9 0.0 0.00014 21.7 0.0 1.5 1 0 0 1 1 1 1 PAN domain NDUF_B8 PF05821.11 PSC69716.1 - 0.063 13.1 0.2 0.093 12.6 0.2 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) AA_permease_2 PF13520.6 PSC69717.1 - 2.8e-21 75.9 30.9 3.2e-21 75.7 30.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 PSC69717.1 - 0.00011 21.0 22.5 0.00013 20.7 22.5 1.1 1 0 0 1 1 1 1 Amino acid permease G-patch_2 PF12656.7 PSC69717.1 - 0.0014 18.7 0.0 0.0028 17.7 0.0 1.4 1 0 0 1 1 1 1 G-patch domain Kinesin PF00225.23 PSC69718.1 - 1.6e-39 135.8 0.0 2.9e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain rve PF00665.26 PSC69718.1 - 2e-18 66.7 0.0 6.7e-18 65.0 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Microtub_bd PF16796.5 PSC69718.1 - 2.7e-07 30.7 0.0 5.6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding rve_3 PF13683.6 PSC69718.1 - 0.021 14.6 0.0 0.058 13.2 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain AAA_22 PF13401.6 PSC69718.1 - 0.09 13.1 1.1 20 5.4 0.0 3.3 2 1 1 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 PSC69718.1 - 0.16 12.0 0.4 29 4.8 0.0 3.1 3 0 0 3 3 3 0 50S ribosome-binding GTPase Herpes_UL14 PF03580.14 PSC69718.1 - 1.1 9.5 8.3 0.9 9.8 5.6 2.3 2 0 0 2 2 2 0 Herpesvirus UL14-like protein ProRS-C_1 PF09180.11 PSC69719.1 - 6.8e-10 39.0 0.0 1.3e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 PSC69719.1 - 2.4e-08 34.0 0.0 5.8e-08 32.8 0.0 1.6 2 0 0 2 2 2 1 Anticodon binding domain DUF2057 PF09829.9 PSC69719.1 - 0.0043 17.3 0.0 0.0043 17.3 0.0 3.4 2 1 0 3 3 3 1 Uncharacterized protein conserved in bacteria (DUF2057) Pkinase PF00069.25 PSC69721.1 - 2.5e-42 145.1 0.0 4.3e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC69721.1 - 9.2e-20 71.0 0.0 1.3e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1538 PF07556.11 PSC69722.1 - 8.6e-100 332.3 39.6 1.3e-53 181.5 16.5 3.4 2 1 0 2 2 2 2 Protein of unknown function (DUF1538) WD40 PF00400.32 PSC69723.1 - 3.9e-47 157.3 3.7 2.5e-09 37.6 0.2 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.11 PSC69723.1 - 5.2e-13 48.3 8.1 1.2e-12 47.1 8.1 1.7 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 PSC69723.1 - 8.6e-13 48.4 0.0 0.013 15.8 0.0 5.1 3 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PSC69723.1 - 8.1e-06 25.0 0.1 0.082 11.9 0.0 3.4 3 1 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 PSC69723.1 - 9.4e-05 21.9 0.0 0.0009 18.7 0.0 2.4 3 0 0 3 3 3 1 Neuroblastoma-amplified sequence, N terminal WD40_like PF17005.5 PSC69723.1 - 0.19 11.0 0.0 16 4.7 0.0 2.3 1 1 1 2 2 2 0 WD40-like domain DUF563 PF04577.14 PSC69724.1 - 2.4e-12 47.4 0.8 4e-12 46.7 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF563) DUF4235 PF14019.6 PSC69724.1 - 5.2 7.2 10.3 2.9 8.0 7.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) GTP_EFTU PF00009.27 PSC69725.1 - 1.6e-20 73.4 0.0 2.7e-20 72.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 PSC69725.1 - 4e-05 23.9 1.3 0.00031 21.1 0.2 2.6 3 0 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PSC69725.1 - 0.00039 20.5 0.2 0.0031 17.6 0.2 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Homeodomain PF00046.29 PSC69726.1 - 0.08 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Homeodomain Methyltr_RsmB-F PF01189.17 PSC69727.1 - 3.1e-70 235.9 0.0 5.6e-70 235.1 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 PSC69727.1 - 7.8e-08 32.7 0.0 2.9e-07 30.9 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 PSC69727.1 - 6.7e-06 26.0 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein FtsJ PF01728.19 PSC69727.1 - 0.00013 22.1 0.1 0.00029 21.0 0.1 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 PSC69727.1 - 0.0057 16.5 0.0 0.012 15.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ribosomal_S10 PF00338.22 PSC69728.1 - 1.3e-43 147.2 1.3 2.9e-27 94.7 0.1 2.4 2 1 0 2 2 2 2 Ribosomal protein S10p/S20e AA_permease_2 PF13520.6 PSC69729.1 - 6.5e-32 110.9 14.5 8e-32 110.6 14.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 PSC69729.1 - 6.1e-13 48.2 11.0 8.2e-13 47.8 11.0 1.1 1 0 0 1 1 1 1 Amino acid permease Neur_chan_memb PF02932.16 PSC69730.1 - 4.3e-10 40.0 0.3 1.3e-09 38.5 0.3 1.7 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Neur_chan_LBD PF02931.23 PSC69730.1 - 0.075 12.5 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel ligand binding domain PLAT PF01477.23 PSC69731.1 - 6e-14 52.6 0.0 9.6e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 PLAT/LH2 domain SpoIIE PF07228.12 PSC69731.1 - 7e-08 32.6 4.5 1.6e-07 31.5 0.4 2.8 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 PSC69731.1 - 1.7e-07 31.2 0.0 0.00081 19.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 PSC69731.1 - 0.0005 19.8 0.1 0.0083 15.8 0.1 2.6 1 1 0 1 1 1 1 Protein phosphatase 2C PLAT PF01477.23 PSC69732.1 - 4.6e-14 53.0 0.0 7.6e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 PLAT/LH2 domain SpoIIE PF07228.12 PSC69732.1 - 6e-08 32.8 4.4 1.5e-07 31.6 0.3 2.8 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 PSC69732.1 - 1.6e-07 31.2 0.0 0.00079 19.1 0.0 2.2 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.6 PSC69732.1 - 0.00047 19.9 0.1 0.008 15.8 0.1 2.6 1 1 0 1 1 1 1 Protein phosphatase 2C Gal-3-0_sulfotr PF06990.11 PSC69733.1 - 3e-08 32.9 0.4 9.3e-06 24.8 0.0 2.1 2 0 0 2 2 2 2 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.14 PSC69733.1 - 1.9e-05 24.7 0.0 6.1e-05 23.1 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase family AA_kinase PF00696.28 PSC69734.1 - 1.2e-08 34.9 0.7 6.8e-05 22.6 0.1 2.5 1 1 1 2 2 2 2 Amino acid kinase family Acetyltransf_7 PF13508.7 PSC69734.1 - 5.5e-06 26.7 0.1 1.4e-05 25.4 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PSC69734.1 - 5.9e-05 23.3 0.0 0.00016 21.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PSC69734.1 - 0.041 13.8 0.0 0.081 12.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PSC69734.1 - 0.067 13.3 0.0 0.28 11.3 0.0 2.1 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain Fasciclin PF02469.22 PSC69735.1 - 2.6e-20 73.0 0.0 3.5e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain TPT PF03151.16 PSC69736.1 - 8e-17 61.5 20.8 1.1e-16 61.1 20.8 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family FHA PF00498.26 PSC69736.1 - 0.0046 17.3 0.0 0.0083 16.5 0.0 1.4 1 0 0 1 1 1 1 FHA domain EamA PF00892.20 PSC69736.1 - 0.01 16.0 8.5 0.01 16.0 8.5 2.3 2 0 0 2 2 2 0 EamA-like transporter family RNA_pol_Rpc4 PF05132.14 PSC69736.1 - 1 9.8 12.3 4.2 7.8 1.7 2.5 2 0 0 2 2 2 0 RNA polymerase III RPC4 FPL PF09758.9 PSC69739.1 - 1.6e-58 196.9 0.0 2.4e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein RAI16-like PF10257.9 PSC69739.1 - 0.0007 18.6 0.0 0.012 14.5 0.0 2.6 2 1 0 2 2 2 1 Retinoic acid induced 16-like protein Spt20 PF12090.8 PSC69739.1 - 0.64 9.6 7.1 1.1 8.8 7.1 1.3 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 PSC69739.1 - 8.4 6.3 14.0 17 5.3 14.0 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SNF2_N PF00176.23 PSC69740.1 - 3.3e-49 167.5 0.0 5.6e-49 166.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC69740.1 - 2.7e-16 59.9 0.0 6.1e-16 58.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 PSC69740.1 - 0.02 14.1 0.0 0.046 12.9 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 PSC69740.1 - 0.051 13.6 0.0 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit Glyco_tran_28_C PF04101.16 PSC69741.1 - 3.5e-18 66.2 0.0 5.2e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain EXOSC1 PF10447.9 PSC69741.1 - 7.2e-15 55.5 2.8 1.9e-09 38.1 0.3 2.4 1 1 1 2 2 2 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 PSC69741.1 - 2.7e-09 36.7 0.1 8.7e-09 35.0 0.0 2.0 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.23 PSC69741.1 - 0.045 14.1 0.2 0.35 11.2 0.2 2.2 1 1 0 1 1 1 0 S1 RNA binding domain Glyco_trans_1_3 PF13528.6 PSC69741.1 - 0.12 11.6 0.1 0.3 10.3 0.0 1.6 2 0 0 2 2 2 0 Glycosyl transferase family 1 Smr PF01713.21 PSC69742.1 - 1.2e-06 28.8 1.9 2.4e-06 27.8 0.9 2.0 2 0 0 2 2 2 1 Smr domain DUF1771 PF08590.10 PSC69742.1 - 0.0094 16.3 14.3 0.022 15.1 14.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) TOM20_plant PF06552.12 PSC69743.1 - 2.3e-54 184.0 0.0 2.7e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_11 PF13414.6 PSC69743.1 - 3e-08 33.2 0.1 6e-05 22.7 0.1 3.4 2 1 1 3 3 3 1 TPR repeat TPR_1 PF00515.28 PSC69743.1 - 0.0027 17.4 1.4 4.2 7.3 0.0 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 PSC69743.1 - 0.009 16.1 12.0 0.51 10.6 0.0 4.8 3 2 2 5 5 5 2 Tetratricopeptide repeat T3SS_needle_E PF08988.10 PSC69743.1 - 0.014 15.5 0.5 0.032 14.4 0.5 1.6 1 0 0 1 1 1 0 Type III secretion system, cytoplasmic E component of needle TPR_12 PF13424.6 PSC69743.1 - 0.076 13.3 3.7 24 5.3 0.0 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 PSC69743.1 - 0.12 13.3 10.8 2.2 9.3 0.2 4.3 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 PSC69743.1 - 0.16 12.7 9.4 0.46 11.2 0.7 3.6 2 2 1 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 PSC69743.1 - 0.33 11.3 4.5 0.51 10.7 0.0 3.5 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.6 PSC69743.1 - 0.38 10.9 5.9 14 6.0 0.1 4.0 4 2 1 5 5 5 0 Tetratricopeptide repeat VWA PF00092.28 PSC69744.1 - 7.3e-18 65.4 0.2 1.3e-17 64.6 0.2 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PSC69744.1 - 2.1e-07 31.5 0.1 4.9e-07 30.4 0.1 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Laminin_G_3 PF13385.6 PSC69744.1 - 4.4e-07 30.2 5.6 2.1e-06 27.9 5.6 2.1 1 1 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Copine PF07002.16 PSC69744.1 - 4.6e-07 29.5 0.1 8.2e-07 28.7 0.1 1.3 1 0 0 1 1 1 1 Copine VWA_CoxE PF05762.14 PSC69744.1 - 0.0026 17.2 0.1 0.0055 16.1 0.1 1.4 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA_3 PF13768.6 PSC69744.1 - 0.0041 17.1 0.0 0.0092 15.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 PSC69744.1 - 0.017 15.3 0.1 0.027 14.6 0.1 1.2 1 0 0 1 1 1 0 vWA found in TerF C terminus ABC_membrane_2 PF06472.15 PSC69745.1 - 1.6e-121 404.9 0.2 3.2e-67 226.8 0.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.27 PSC69745.1 - 3e-32 112.0 0.0 6.4e-18 65.6 0.0 2.6 2 1 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 PSC69745.1 - 2.3e-09 37.5 0.6 0.0012 18.7 0.0 2.6 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PSC69745.1 - 1e-07 31.6 0.2 0.014 15.1 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.6 PSC69745.1 - 8.3e-07 29.7 0.1 0.029 14.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 PSC69745.1 - 9.3e-07 29.4 1.7 0.021 15.2 0.1 3.8 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 PSC69745.1 - 0.00013 22.2 0.2 0.085 13.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.21 PSC69745.1 - 0.00038 19.9 0.6 0.4 10.0 0.1 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI SMC_N PF02463.19 PSC69745.1 - 0.00039 19.9 0.2 1.1 8.7 0.0 3.0 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 PSC69745.1 - 0.0009 18.4 0.1 0.057 12.5 0.0 2.2 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_27 PF13514.6 PSC69745.1 - 0.0024 17.5 0.0 2.6 7.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 PSC69745.1 - 0.0058 16.2 0.0 4.6 6.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing dynein motor region TraG-D_C PF12696.7 PSC69745.1 - 0.0079 16.2 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 TraM recognition site of TraD and TraG NACHT PF05729.12 PSC69745.1 - 0.019 14.9 0.2 1.1 9.1 0.0 2.7 2 0 0 2 2 2 0 NACHT domain AAA_18 PF13238.6 PSC69745.1 - 0.025 15.1 1.0 5 7.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_30 PF13604.6 PSC69745.1 - 0.025 14.3 0.3 5.3 6.7 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 PSC69745.1 - 0.038 14.4 0.8 2.1 8.8 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PSC69745.1 - 0.16 12.0 0.6 6.1 6.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 PSC69745.1 - 0.2 11.6 0.8 17 5.3 0.1 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain Peptidase_M44 PF03410.13 PSC69745.1 - 0.31 9.6 0.0 0.45 9.0 0.0 1.1 1 0 0 1 1 1 0 Metallopeptidase from vaccinia pox DUF3584 PF12128.8 PSC69745.1 - 0.6 7.6 1.2 1.2 6.6 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) Ribosomal_L18p PF00861.22 PSC69746.1 - 1.3e-47 160.9 0.2 1.4e-47 160.8 0.2 1.0 1 0 0 1 1 1 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast LigB PF02900.18 PSC69746.1 - 0.026 13.6 0.0 0.03 13.4 0.0 1.0 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase NifU PF01106.17 PSC69746.1 - 0.05 13.8 0.0 0.088 13.0 0.0 1.4 1 0 0 1 1 1 0 NifU-like domain DNA_photolyase PF00875.18 PSC69746.1 - 0.15 12.0 0.0 0.3 11.1 0.0 1.5 1 1 1 2 2 2 0 DNA photolyase RAP PF08373.10 PSC69747.1 - 4e-15 55.6 0.0 6.4e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.15 PSC69747.1 - 3.5e-11 42.9 0.5 0.005 16.7 0.0 5.8 4 2 4 8 8 8 3 FAST kinase-like protein, subdomain 1 MTES_1575 PF18741.1 PSC69747.1 - 3.4e-07 30.3 0.4 9.4e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 REase_MTES_1575 SAP PF02037.27 PSC69747.1 - 6.7e-07 28.9 0.2 1.7e-06 27.7 0.2 1.6 1 0 0 1 1 1 1 SAP domain TFIIA PF03153.13 PSC69747.1 - 0.97 9.4 41.6 0.54 10.2 21.2 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Rhomboid PF01694.22 PSC69748.1 - 1.8e-18 67.0 12.1 3.1e-18 66.2 12.1 1.4 1 0 0 1 1 1 1 Rhomboid family DUF5378 PF17349.2 PSC69748.1 - 0.17 11.2 0.1 0.17 11.2 0.1 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5378) CPSF73-100_C PF11718.8 PSC69749.1 - 1.8e-31 109.4 0.0 3.1e-31 108.6 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term SIR2 PF02146.17 PSC69749.1 - 2.8e-28 99.0 0.1 2.2e-20 73.3 0.0 2.5 1 1 1 2 2 2 2 Sir2 family Lactamase_B PF00753.27 PSC69749.1 - 1.5e-10 41.4 2.8 1.5e-10 41.4 2.8 2.5 4 0 0 4 4 4 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 PSC69749.1 - 1.9e-10 40.5 0.0 3.3e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 PSC69749.1 - 1.3e-06 28.1 2.2 4.4e-06 26.3 2.2 1.9 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 PSC69749.1 - 0.0076 16.2 0.5 0.028 14.3 0.5 1.9 1 1 0 1 1 1 1 Beta-lactamase superfamily domain TPP_enzyme_M PF00205.22 PSC69749.1 - 0.062 13.0 0.1 9.2 6.0 0.0 2.8 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain CPSF73-100_C PF11718.8 PSC69750.1 - 1.3e-31 109.8 0.0 1.9e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 PSC69750.1 - 1.5e-28 99.3 0.0 3e-28 98.3 0.0 1.6 1 0 0 1 1 1 1 Beta-Casp domain RMMBL PF07521.12 PSC69750.1 - 1.3e-17 63.5 0.1 2.6e-17 62.5 0.1 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 PSC69750.1 - 7.7e-17 61.9 3.8 7.7e-17 61.9 3.8 2.4 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily Lactamase_B_6 PF16661.5 PSC69750.1 - 3e-15 56.2 0.0 2.8e-14 53.0 0.0 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 PSC69750.1 - 6.5e-08 32.3 3.0 5.1e-07 29.4 1.4 2.7 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 PSC69750.1 - 0.00014 21.8 0.1 0.00061 19.7 0.0 2.0 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 PSC69750.1 - 0.068 12.4 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative beta-lactamase-like family DUF4922 PF16269.5 PSC69751.1 - 0.0081 16.0 0.1 0.026 14.3 0.1 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF4922) Ribosomal_L1 PF00687.21 PSC69752.1 - 7.6e-47 159.7 3.5 9.3e-47 159.4 3.5 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family TetR PF13972.6 PSC69752.1 - 0.18 11.5 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial transcriptional repressor SKN1 PF03935.15 PSC69753.1 - 2.3e-07 29.6 0.0 3e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) PPR_2 PF13041.6 PSC69755.1 - 1.3e-80 265.4 18.0 9.6e-15 54.5 0.0 8.3 1 1 7 8 8 8 8 PPR repeat family PPR PF01535.20 PSC69755.1 - 3.3e-62 202.5 13.8 1.1e-09 37.9 0.1 9.5 9 0 0 9 9 9 8 PPR repeat PPR_3 PF13812.6 PSC69755.1 - 1.3e-58 195.0 1.2 1.3e-14 54.0 0.5 6.2 4 2 1 5 5 5 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 PSC69755.1 - 3.4e-54 180.2 0.0 2.1e-08 33.7 0.0 9.7 9 0 0 9 9 9 8 PPR repeat PPR_long PF17177.4 PSC69755.1 - 5.7e-27 94.5 1.8 6.7e-16 58.3 0.5 3.1 1 1 2 3 3 3 2 Pentacotripeptide-repeat region of PRORP Cyclin_C PF02984.19 PSC69755.1 - 5.6e-06 26.4 0.0 5.6e-06 26.4 0.0 2.1 2 0 0 2 2 1 1 Cyclin, C-terminal domain Clathrin PF00637.20 PSC69755.1 - 6.6e-06 26.0 0.0 0.0015 18.4 0.0 3.3 3 1 0 3 3 3 1 Region in Clathrin and VPS TPR_1 PF00515.28 PSC69755.1 - 2.2e-05 24.0 0.1 4.2 7.4 0.0 6.1 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 PSC69755.1 - 5.1e-05 23.7 9.3 9.2 7.4 0.1 7.4 5 2 2 7 7 6 1 Tetratricopeptide repeat Cyclin_N PF00134.23 PSC69755.1 - 9e-05 22.2 0.0 0.00023 20.9 0.0 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain PYRIN PF02758.16 PSC69755.1 - 0.015 15.4 0.4 29 4.9 0.0 3.9 4 0 0 4 4 4 0 PAAD/DAPIN/Pyrin domain TPR_7 PF13176.6 PSC69755.1 - 0.095 12.8 4.6 3.5 7.9 0.0 5.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 PSC69755.1 - 0.1 13.3 1.9 84 4.1 0.1 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 PSC69755.1 - 0.24 11.7 2.8 10 6.5 0.1 4.4 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 PSC69755.1 - 6.2 7.2 7.6 7.7 6.9 0.2 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat SIR2 PF02146.17 PSC69756.1 - 4.7e-06 26.6 0.0 7.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Sir2 family Chloroa_b-bind PF00504.21 PSC69757.1 - 3.2e-14 53.8 4.9 2.5e-11 44.4 1.1 2.2 1 1 1 2 2 2 2 Chlorophyll A-B binding protein RNase_T PF00929.24 PSC69757.1 - 7e-08 33.2 0.0 1.1e-07 32.6 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Cluap1 PF10234.9 PSC69758.1 - 4.5e-36 124.6 0.0 1.4e-18 67.2 0.0 2.1 2 0 0 2 2 2 2 Clusterin-associated protein-1 Peptidase_S26 PF10502.9 PSC69758.1 - 0.02 14.7 0.6 0.072 12.9 0.1 1.9 2 0 0 2 2 2 0 Signal peptidase, peptidase S26 CLZ PF16526.5 PSC69758.1 - 0.024 15.0 4.1 3.6 8.0 0.3 2.6 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels MscS_porin PF12795.7 PSC69758.1 - 0.07 12.7 0.2 0.07 12.7 0.2 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel porin domain FliJ PF02050.16 PSC69758.1 - 0.091 13.0 10.2 0.39 10.9 0.1 3.1 2 1 2 4 4 4 0 Flagellar FliJ protein CENP-Q PF13094.6 PSC69758.1 - 0.38 10.9 6.1 1.9 8.6 0.1 2.2 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Biotin_lipoyl PF00364.22 PSC69759.1 - 2.9e-23 81.5 0.4 4.8e-23 80.8 0.4 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 PSC69759.1 - 1.8e-09 37.2 0.0 0.00085 19.1 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like RnfC_N PF13375.6 PSC69759.1 - 8e-06 25.7 0.2 0.00064 19.6 0.1 2.7 1 1 2 3 3 3 1 RnfC Barrel sandwich hybrid domain PTS_EIIA_1 PF00358.20 PSC69759.1 - 0.00084 19.1 0.6 0.39 10.5 0.1 3.6 2 1 1 4 4 4 1 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 GCV_H PF01597.19 PSC69759.1 - 0.003 17.4 0.1 0.0076 16.1 0.1 1.6 1 0 0 1 1 1 1 Glycine cleavage H-protein QRPTase_N PF02749.16 PSC69759.1 - 0.0074 16.3 0.1 1.4 9.0 0.0 2.4 1 1 1 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Peptidase_M23 PF01551.22 PSC69759.1 - 0.015 15.5 0.6 2.2 8.5 0.0 3.3 1 1 1 3 3 3 0 Peptidase family M23 HlyD_D23 PF16576.5 PSC69759.1 - 0.016 14.5 0.1 0.98 8.6 0.0 2.3 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion NQRA PF05896.11 PSC69759.1 - 0.043 13.2 0.7 5.4 6.4 0.1 3.0 2 1 1 3 3 3 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) HlyD_2 PF12700.7 PSC69759.1 - 0.053 12.3 0.1 0.096 11.4 0.0 1.4 2 0 0 2 2 2 0 HlyD family secretion protein HlyD_3 PF13437.6 PSC69759.1 - 0.082 13.6 0.0 5 7.9 0.0 2.4 2 0 0 2 2 2 0 HlyD family secretion protein YqfD PF06898.11 PSC69759.1 - 0.13 11.1 0.5 2.1 7.1 0.3 2.1 1 1 1 2 2 2 0 Putative stage IV sporulation protein YqfD FAP PF07174.11 PSC69759.1 - 0.27 10.7 19.7 0.33 10.4 19.7 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) GBP PF02263.19 PSC69763.1 - 5.2e-31 107.9 0.0 1.1e-30 106.8 0.0 1.5 1 1 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 PSC69763.1 - 7.9e-08 32.1 0.0 1.1e-07 31.6 0.0 1.1 1 0 0 1 1 1 1 Guanylate-binding protein, C-terminal domain RHD3 PF05879.12 PSC69763.1 - 0.056 11.6 0.0 0.081 11.1 0.0 1.2 1 0 0 1 1 1 0 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 PSC69763.1 - 0.14 12.2 0.0 0.25 11.4 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF1713 PF08213.11 PSC69764.1 - 1e-05 25.3 19.7 1.6e-05 24.7 19.7 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Peptidase_C1 PF00112.23 PSC69765.1 - 5.9e-52 176.9 0.3 9.9e-52 176.2 0.3 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PSC69765.1 - 0.0062 17.0 0.0 0.021 15.2 0.0 1.9 2 1 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PSC69765.1 - 0.11 11.2 0.2 0.35 9.6 0.0 1.7 2 0 0 2 2 2 0 Peptidase C1-like family Ephrin_rec_like PF07699.13 PSC69766.1 - 3.1e-79 260.5 331.6 8e-08 31.9 8.8 36.2 15 8 19 36 36 36 27 Putative ephrin-receptor like NCD3G PF07562.14 PSC69766.1 - 7.1e-20 70.7 215.1 0.029 14.3 4.1 28.5 19 6 9 31 31 31 22 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 PSC69766.1 - 5.5e-08 33.1 217.0 0.058 13.8 0.6 33.2 26 9 6 32 32 32 20 TNFR/NGFR cysteine-rich region MRG PF05712.13 PSC69767.1 - 2.8e-35 121.4 0.0 3.9e-35 121.0 0.0 1.2 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 PSC69767.1 - 6.4e-07 29.2 1.5 1.2e-06 28.3 1.5 1.4 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Chromo PF00385.24 PSC69767.1 - 0.0029 17.5 0.6 0.006 16.5 0.6 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1325 PF07039.11 PSC69767.1 - 0.0076 16.3 0.1 0.014 15.5 0.1 1.4 1 0 0 1 1 1 1 SGF29 tudor-like domain DUF1451 PF07295.11 PSC69767.1 - 1 9.4 3.6 10 6.2 0.4 2.4 2 0 0 2 2 2 0 Zinc-ribbon containing domain SGT1 PF07093.11 PSC69768.1 - 1.1e-118 397.2 0.0 6.3e-94 315.5 0.0 3.1 3 0 0 3 3 3 3 SGT1 protein DNA_pol_phi PF04931.13 PSC69768.1 - 0.77 7.8 4.5 1.1 7.3 4.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 PSC69768.1 - 5.8 7.4 8.3 3.1 8.2 3.0 2.4 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TPR_12 PF13424.6 PSC69769.1 - 4e-09 36.6 0.3 4e-09 36.6 0.3 3.3 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 PSC69769.1 - 4.8e-09 36.6 1.5 2e-05 25.0 0.1 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 PSC69769.1 - 3.7e-08 32.9 0.7 0.005 16.6 0.2 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PSC69769.1 - 1.4e-07 31.1 1.3 0.05 13.7 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 PSC69769.1 - 5.7e-06 26.1 1.0 0.0016 18.5 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 PSC69769.1 - 0.00046 20.0 1.0 0.78 9.7 0.3 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 PSC69769.1 - 0.00052 19.8 9.4 0.0024 17.8 0.1 3.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 PSC69769.1 - 0.0079 16.8 2.8 1.2 9.9 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 PSC69769.1 - 0.023 14.4 0.0 9.6 6.0 0.3 2.7 3 0 0 3 3 3 0 TPR repeat SNAP PF14938.6 PSC69769.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_14 PF13428.6 PSC69769.1 - 1 10.4 0.0 1 10.4 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat DUF3682 PF12446.8 PSC69769.1 - 7.2 7.1 10.3 2.5 8.6 6.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) Ran_BP1 PF00638.18 PSC69770.1 - 1.5e-39 135.1 0.3 2.6e-39 134.3 0.3 1.4 1 0 0 1 1 1 1 RanBP1 domain Fasciclin PF02469.22 PSC69770.1 - 7.2e-11 42.4 0.0 0.00011 22.4 0.0 2.5 2 0 0 2 2 2 2 Fasciclin domain DUF599 PF04654.12 PSC69771.1 - 2.2e-35 122.0 7.0 2.9e-35 121.6 7.0 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF599 ArAE_2_N PF10337.9 PSC69771.1 - 2.4 7.1 5.9 0.28 10.2 2.0 1.5 1 1 1 2 2 2 0 Putative ER transporter, 6TM, N-terminal Y_phosphatase PF00102.27 PSC69772.1 - 3.3e-51 174.1 0.0 5.3e-50 170.2 0.0 2.6 1 1 0 1 1 1 1 Protein-tyrosine phosphatase ATG101 PF07855.12 PSC69772.1 - 1.2e-43 148.8 0.3 1.8e-43 148.2 0.3 1.3 1 0 0 1 1 1 1 Autophagy-related protein 101 Fasciclin PF02469.22 PSC69772.1 - 7.4e-13 48.8 0.0 2.3e-06 27.9 0.0 2.8 3 0 0 3 3 3 2 Fasciclin domain DSPc PF00782.20 PSC69772.1 - 0.0024 17.7 0.3 0.0044 16.8 0.3 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PSC69772.1 - 0.041 13.8 0.0 0.078 12.9 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Pex14_N PF04695.13 PSC69773.1 - 1e-23 84.7 2.7 1e-23 84.7 2.7 3.5 3 1 1 4 4 4 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5572 PF17733.1 PSC69773.1 - 5.4e-10 38.9 4.7 1.5e-09 37.6 4.7 1.8 1 0 0 1 1 1 1 Family of unknown function (DUF5572) Laminin_II PF06009.12 PSC69773.1 - 0.014 15.4 0.0 0.024 14.7 0.0 1.2 1 0 0 1 1 1 0 Laminin Domain II NAD_Gly3P_dh_C PF07479.14 PSC69774.1 - 6e-49 166.0 0.2 1.1e-48 165.2 0.2 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 PSC69774.1 - 1.5e-48 164.7 0.0 2.6e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 PSC69774.1 - 1.5e-06 28.7 0.0 4.7e-06 27.1 0.0 1.9 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 PSC69774.1 - 1.6e-05 25.1 0.0 3.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 PSC69774.1 - 0.00046 20.1 0.0 0.0015 18.4 0.0 1.9 1 1 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 PSC69774.1 - 0.00079 18.8 0.2 0.0017 17.7 0.0 1.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 PSC69774.1 - 0.0072 15.6 0.1 0.018 14.3 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 PSC69774.1 - 0.013 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Rossmann-like PF10727.9 PSC69774.1 - 0.015 15.1 0.2 0.066 13.1 0.2 2.1 1 1 0 1 1 1 0 Rossmann-like domain ApbA_C PF08546.11 PSC69774.1 - 0.036 14.3 0.0 0.37 11.0 0.0 2.3 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Pyr_redox PF00070.27 PSC69774.1 - 0.038 14.5 0.3 1.2 9.8 0.0 3.1 3 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.16 PSC69774.1 - 0.047 13.3 0.0 0.078 12.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA FAD_oxidored PF12831.7 PSC69774.1 - 0.056 12.8 0.8 0.11 11.8 0.2 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase GIDA PF01134.22 PSC69774.1 - 0.084 11.9 0.1 0.13 11.3 0.1 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A 2-Hacid_dh_C PF02826.19 PSC69774.1 - 0.11 11.9 0.0 0.22 10.8 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SNF2_N PF00176.23 PSC69775.1 - 7.6e-55 186.0 0.0 1.1e-54 185.4 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 PSC69776.1 - 1.1e-46 158.9 0.2 1.5e-46 158.4 0.2 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC69776.1 - 3.8e-32 110.9 0.0 2.1e-31 108.5 0.0 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 PSC69776.1 - 1.8e-05 24.1 0.0 2.9e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 PSC69776.1 - 0.00046 20.2 0.0 0.0011 19.0 0.0 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 PSC69776.1 - 0.0014 18.0 0.1 0.11 11.8 0.0 2.3 1 1 1 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit GRP PF07172.11 PSC69776.1 - 0.013 16.1 27.4 0.027 15.2 27.4 1.5 1 0 0 1 1 1 0 Glycine rich protein family OTU PF02338.19 PSC69777.1 - 4e-13 50.0 0.0 7.2e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease SBP56 PF05694.11 PSC69777.1 - 0.0002 20.3 0.0 0.00096 18.1 0.0 1.9 1 1 0 1 1 1 1 56kDa selenium binding protein (SBP56) Peptidase_C65 PF10275.9 PSC69777.1 - 0.074 12.5 0.0 12 5.3 0.0 2.2 2 0 0 2 2 2 0 Peptidase C65 Otubain EBP PF05241.12 PSC69778.1 - 5.2e-56 188.9 11.8 6.4e-56 188.6 11.8 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF4381 PF14316.6 PSC69778.1 - 0.35 11.1 0.1 0.35 11.1 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) Phage_holin_3_6 PF07332.11 PSC69778.1 - 1.1 9.4 3.7 19 5.3 2.3 2.3 2 1 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III SPT2 PF08243.11 PSC69779.1 - 2.5e-14 53.7 7.8 4.7e-14 52.8 7.8 1.4 1 0 0 1 1 1 1 SPT2 chromatin protein SecY PF00344.20 PSC69780.1 - 2.8e-92 309.3 3.4 3.4e-92 309.0 3.4 1.1 1 0 0 1 1 1 1 SecY translocase NifU PF01106.17 PSC69781.1 - 2.5e-38 130.0 1.1 2.4e-25 88.5 0.0 2.3 2 0 0 2 2 2 2 NifU-like domain FKBP26_C PF18046.1 PSC69781.1 - 0.11 12.6 0.0 11 6.2 0.0 2.6 3 0 0 3 3 3 0 FKBP26_C-terminal Pup PF05639.11 PSC69781.1 - 5.4 8.0 7.0 56 4.8 0.2 3.0 2 1 1 3 3 3 0 Pup-like protein Tom7 PF08038.12 PSC69782.1 - 4.1e-11 42.4 0.1 4.8e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 TOM7 family Peptidase_S24 PF00717.23 PSC69783.1 - 0.0002 21.3 0.0 0.00035 20.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like DUF3067 PF11267.8 PSC69784.1 - 7.9e-31 106.6 0.0 9.9e-31 106.2 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3067) Helicase_C_2 PF13307.6 PSC69785.1 - 6.5e-53 179.4 0.0 1.1e-52 178.6 0.0 1.4 1 0 0 1 1 1 1 Helicase C-terminal domain DEAD_2 PF06733.15 PSC69785.1 - 9.1e-46 155.7 0.8 1.3e-45 155.1 0.8 1.2 1 0 0 1 1 1 1 DEAD_2 DEAD PF00270.29 PSC69785.1 - 6.8e-06 26.0 0.0 0.00014 21.7 0.0 2.3 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 PSC69785.1 - 0.0011 18.9 0.1 0.067 13.2 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit HBB PF06777.11 PSC69785.1 - 0.04 13.6 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 Helical and beta-bridge domain Mg_chelatase PF01078.21 PSC69785.1 - 0.1 12.0 0.1 0.19 11.1 0.1 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI SNARE PF05739.19 PSC69786.1 - 2.7e-08 33.7 0.5 4.8e-08 32.9 0.5 1.4 1 0 0 1 1 1 1 SNARE domain Prominin PF05478.11 PSC69786.1 - 0.062 11.3 0.1 0.082 10.8 0.1 1.1 1 0 0 1 1 1 0 Prominin DUF3040 PF11239.8 PSC69786.1 - 1.1 9.6 7.5 0.11 12.8 0.7 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Lipase_3 PF01764.25 PSC69787.1 - 1.2e-19 70.6 0.0 2.4e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 PSC69787.1 - 0.0011 18.6 0.8 0.011 15.3 0.8 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Dus PF01207.17 PSC69788.1 - 1.6e-66 224.5 0.0 1.9e-66 224.3 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF2967 PF11179.8 PSC69788.1 - 2.6 6.0 4.3 3.3 5.7 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) E1-E2_ATPase PF00122.20 PSC69789.1 - 4.6e-40 137.1 2.2 9.3e-40 136.1 2.2 1.5 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 PSC69789.1 - 4.7e-38 131.6 1.6 1e-37 130.5 0.2 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 PSC69789.1 - 4.7e-09 36.6 0.2 9.5e-09 35.6 0.2 1.5 1 0 0 1 1 1 1 Heavy-metal-associated domain HAD PF12710.7 PSC69789.1 - 2.1e-05 25.0 0.2 7.2e-05 23.3 0.2 1.9 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 PSC69789.1 - 0.003 17.4 0.1 0.0054 16.5 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase zf-AN1 PF01428.16 PSC69790.1 - 5.9e-08 32.8 12.7 8.8e-08 32.2 12.7 1.3 1 0 0 1 1 1 1 AN1-like Zinc finger FAP PF07174.11 PSC69790.1 - 0.035 13.6 11.5 0.037 13.5 11.5 1.1 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) Herpes_UL32 PF06070.11 PSC69790.1 - 0.11 10.3 2.1 0.11 10.2 2.1 1.0 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 MIF4G PF02854.19 PSC69791.1 - 2.3e-36 125.4 0.7 3.4e-36 124.9 0.0 1.6 2 0 0 2 2 2 1 MIF4G domain DUF543 PF04418.12 PSC69791.1 - 2.9e-15 56.0 0.1 6.3e-15 54.9 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF543) MA3 PF02847.17 PSC69791.1 - 0.0002 21.3 0.0 0.00063 19.7 0.0 1.8 1 0 0 1 1 1 1 MA3 domain FAM76 PF16046.5 PSC69791.1 - 0.073 12.4 2.8 0.13 11.6 2.8 1.3 1 0 0 1 1 1 0 FAM76 protein Herpes_capsid PF06112.11 PSC69791.1 - 1.2 9.2 8.4 3.3 7.8 8.4 1.7 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PrmA PF06325.13 PSC69792.1 - 4.5e-11 42.7 0.0 6.7e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PSC69792.1 - 4.1e-10 40.2 0.0 1e-09 39.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC69792.1 - 3.9e-08 33.8 0.0 1.1e-07 32.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC69792.1 - 5.1e-08 32.8 0.0 7.6e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PSC69792.1 - 5.3e-06 26.1 0.0 8.8e-06 25.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 PSC69792.1 - 3.2e-05 23.9 0.1 5.2e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 PSC69792.1 - 6.3e-05 22.9 0.0 0.00011 22.1 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.6 PSC69792.1 - 0.00017 21.4 0.0 0.00028 20.8 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 PSC69792.1 - 0.0037 16.6 0.1 0.0081 15.5 0.1 1.6 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Met_10 PF02475.16 PSC69792.1 - 0.0051 16.6 0.1 0.008 15.9 0.1 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Ubie_methyltran PF01209.18 PSC69792.1 - 0.0099 15.2 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_9 PF08003.11 PSC69792.1 - 0.011 14.7 0.0 0.017 14.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.15 PSC69792.1 - 0.012 15.3 0.0 0.02 14.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PCMT PF01135.19 PSC69792.1 - 0.037 13.8 0.2 0.065 13.0 0.2 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DUF5372 PF17342.2 PSC69792.1 - 0.056 13.9 0.0 0.16 12.4 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5372) Methyltransf_16 PF10294.9 PSC69792.1 - 0.098 12.4 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Lysine methyltransferase GidB PF02527.15 PSC69792.1 - 0.15 11.4 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G PRMT5_C PF17286.2 PSC69792.1 - 0.17 11.7 0.0 0.25 11.2 0.0 1.2 1 0 0 1 1 1 0 PRMT5 oligomerisation domain TRF PF08558.10 PSC69792.1 - 0.19 11.3 0.0 4.5 6.8 0.0 2.1 1 1 1 2 2 2 0 Telomere repeat binding factor (TRF) HAD_2 PF13419.6 PSC69793.1 - 0.0001 22.5 0.0 0.00047 20.3 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PSC69793.1 - 0.00041 20.4 0.0 0.00096 19.2 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 PSC69793.1 - 0.012 15.9 0.0 0.62 10.3 0.0 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase CW_binding_2 PF04122.12 PSC69794.1 - 0.0079 16.8 0.2 0.0079 16.8 0.2 2.6 3 0 0 3 3 3 1 Putative cell wall binding repeat 2 WD40 PF00400.32 PSC69796.1 - 2.6e-05 24.9 0.1 0.25 12.3 0.0 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat WD40 PF00400.32 PSC69797.1 - 2.5e-40 135.7 21.7 1.2e-08 35.4 0.0 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC69797.1 - 5.7e-13 49.0 0.0 5.7e-06 26.5 0.0 4.9 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PSC69797.1 - 6.8e-06 25.3 0.0 0.004 16.2 0.0 3.0 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PSC69797.1 - 0.0003 19.6 0.0 0.3 9.7 0.0 3.2 3 1 0 3 3 3 2 Nucleoporin Nup120/160 eIF2A PF08662.11 PSC69797.1 - 0.001 19.0 0.0 0.0073 16.2 0.0 2.3 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Kelch_6 PF13964.6 PSC69797.1 - 0.014 15.7 0.1 0.17 12.2 0.0 2.9 2 0 0 2 2 2 0 Kelch motif Nbas_N PF15492.6 PSC69797.1 - 0.039 13.3 0.6 4 6.7 0.0 2.9 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PALB2_WD40 PF16756.5 PSC69797.1 - 0.2 10.6 1.1 0.53 9.2 0.7 2.0 2 0 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Neur_chan_LBD PF02931.23 PSC69798.1 - 3.2e-09 36.6 0.0 0.00017 21.2 0.0 2.1 2 0 0 2 2 2 2 Neurotransmitter-gated ion-channel ligand binding domain Neur_chan_memb PF02932.16 PSC69798.1 - 3.7e-07 30.5 0.0 6.7e-07 29.6 0.0 1.4 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Sporozoite_P67 PF05642.11 PSC69798.1 - 3.6 5.6 9.5 4.8 5.1 9.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SUR7 PF06687.12 PSC69798.1 - 4.1 7.0 7.1 5.1 6.7 4.8 2.1 2 0 0 2 2 2 0 SUR7/PalI family Rad4 PF03835.15 PSC69799.1 - 5.9e-15 55.2 0.4 3.5e-14 52.7 0.3 2.0 2 0 0 2 2 2 1 Rad4 transglutaminase-like domain Transglut_core PF01841.19 PSC69799.1 - 3.2e-13 50.1 8.2 1.9e-12 47.7 1.2 3.4 3 0 0 3 3 3 2 Transglutaminase-like superfamily Pentapeptide PF00805.22 PSC69801.1 - 3.9e-22 77.5 5.1 2.4e-09 36.7 0.4 3.2 1 1 1 3 3 3 3 Pentapeptide repeats (8 copies) Pentapeptide_3 PF13576.6 PSC69801.1 - 8.5e-11 41.8 0.0 3.9e-05 23.7 0.1 3.1 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) Pentapeptide_4 PF13599.6 PSC69801.1 - 5.9e-09 36.0 0.0 3.8e-06 27.0 0.0 2.2 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) PhoLip_ATPase_C PF16212.5 PSC69805.1 - 3.8e-64 216.8 17.8 3.8e-64 216.8 17.8 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 PSC69805.1 - 3.3e-18 65.2 0.1 3.3e-18 65.2 0.1 2.2 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Hydrolase PF00702.26 PSC69805.1 - 1.6e-10 41.7 2.1 6.3e-06 26.6 0.8 3.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PSC69805.1 - 3.2e-08 33.6 0.0 8.2e-07 29.0 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 PSC69805.1 - 7.3e-08 32.1 0.1 3.9e-07 29.8 0.0 2.4 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase_3 PF08282.12 PSC69805.1 - 0.0026 17.5 0.1 0.0049 16.6 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PSC69805.1 - 0.026 14.9 0.1 1.6 9.1 0.0 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase DUF1080 PF06439.11 PSC69805.1 - 0.03 14.4 0.1 0.24 11.5 0.0 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1080) Sec8_exocyst PF04048.14 PSC69806.1 - 0.12 12.3 2.8 0.066 13.1 0.9 1.5 1 1 0 1 1 1 0 Sec8 exocyst complex component specific domain TFIIA PF03153.13 PSC69806.1 - 3.2 7.7 16.9 3.8 7.4 16.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAS_4 PF08448.10 PSC69806.1 - 9 6.6 8.8 2.2 8.6 3.4 2.5 2 1 1 3 3 3 0 PAS fold NAD_kinase PF01513.21 PSC69807.1 - 1.1e-51 175.8 0.0 1.2e-50 172.4 0.0 2.0 1 1 0 1 1 1 1 ATP-NAD kinase DUF2924 PF11149.8 PSC69809.1 - 0.037 14.4 0.1 0.037 14.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) DUF2924 PF11149.8 PSC69810.1 - 0.037 14.4 0.1 0.037 14.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2924) Polyketide_cyc2 PF10604.9 PSC69811.1 - 0.031 14.5 0.6 0.031 14.5 0.6 2.2 3 1 0 3 3 3 0 Polyketide cyclase / dehydrase and lipid transport SUIM_assoc PF16619.5 PSC69811.1 - 0.035 14.2 4.4 0.07 13.2 4.4 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 COXG PF06240.13 PSC69811.1 - 0.041 13.6 0.0 0.079 12.7 0.0 1.4 1 0 0 1 1 1 0 Carbon monoxide dehydrogenase subunit G (CoxG) Spt20 PF12090.8 PSC69811.1 - 0.17 11.4 2.7 0.22 11.1 2.7 1.1 1 0 0 1 1 1 0 Spt20 family DUF1995 PF09353.10 PSC69812.1 - 8.7e-19 68.3 0.0 1e-18 68.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) mTERF PF02536.14 PSC69813.1 - 5.3e-08 32.2 0.0 2.6e-06 26.6 0.0 2.0 1 1 1 2 2 2 2 mTERF HisG PF01634.18 PSC69814.1 - 3.9e-35 121.2 0.0 5.7e-35 120.7 0.0 1.3 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 PSC69814.1 - 3e-18 65.7 0.0 6.5e-18 64.6 0.0 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain ABC2_membrane PF01061.24 PSC69816.1 - 1.7e-31 109.3 22.5 2.6e-31 108.7 22.5 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PSC69816.1 - 2.7e-23 83.0 0.0 3.8e-23 82.5 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 PSC69816.1 - 5.8e-05 23.5 0.1 0.00011 22.6 0.1 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_21 PF13304.6 PSC69816.1 - 0.00036 20.4 0.0 0.65 9.7 0.1 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 PSC69816.1 - 0.0044 16.7 0.1 0.012 15.3 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 PSC69816.1 - 0.0063 16.4 0.4 0.012 15.6 0.4 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 PSC69816.1 - 0.028 14.7 0.4 0.08 13.2 0.3 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PSC69816.1 - 0.029 14.6 0.3 0.056 13.7 0.3 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PSC69816.1 - 0.063 13.0 1.5 0.16 11.7 1.5 1.7 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 PSC69816.1 - 0.13 12.5 0.1 0.36 11.1 0.1 1.8 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit ABC2_membrane_3 PF12698.7 PSC69816.1 - 0.16 11.0 21.2 0.024 13.7 16.8 1.6 1 1 1 2 2 2 0 ABC-2 family transporter protein AAA_23 PF13476.6 PSC69816.1 - 0.31 11.5 0.1 0.52 10.8 0.1 1.2 1 0 0 1 1 1 0 AAA domain His_Phos_1 PF00300.22 PSC69817.1 - 2.8e-25 89.2 0.0 3.9e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Asparaginase PF00710.20 PSC69818.1 - 3.4e-58 196.4 0.0 4.8e-57 192.6 0.0 2.1 1 1 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 PSC69818.1 - 1.8e-19 70.1 0.0 3.2e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Tom7 PF08038.12 PSC69819.1 - 4.1e-11 42.4 0.1 4.8e-11 42.1 0.1 1.2 1 0 0 1 1 1 1 TOM7 family Ank_2 PF12796.7 PSC69820.1 - 3.5e-28 98.0 0.7 3.4e-12 46.8 0.1 4.1 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC69820.1 - 6.4e-22 77.6 4.0 2.4e-06 28.0 0.2 5.3 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC69820.1 - 1.1e-19 68.4 0.8 0.0019 18.5 0.0 6.6 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 PSC69820.1 - 4.3e-17 61.7 12.1 0.00073 19.9 0.1 6.1 6 0 0 6 6 6 4 Ankyrin repeat UPF0020 PF01170.18 PSC69820.1 - 3.5e-14 53.0 0.2 6e-13 48.9 0.2 2.3 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Ank_5 PF13857.6 PSC69820.1 - 4e-14 52.5 6.3 0.0013 19.0 0.3 5.0 2 2 2 4 4 4 4 Ankyrin repeats (many copies) N6_N4_Mtase PF01555.18 PSC69820.1 - 1.7e-05 24.7 0.0 5.6e-05 23.0 0.0 1.7 2 0 0 2 2 2 1 DNA methylase PrmA PF06325.13 PSC69820.1 - 0.0068 15.8 0.4 0.015 14.7 0.4 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Cons_hypoth95 PF03602.15 PSC69820.1 - 0.007 16.0 0.1 0.012 15.3 0.1 1.4 1 0 0 1 1 1 1 Conserved hypothetical protein 95 AviRa PF11599.8 PSC69820.1 - 0.014 14.8 0.0 4.7 6.6 0.0 2.3 2 0 0 2 2 2 0 RRNA methyltransferase AviRa JmjC PF02373.22 PSC69821.1 - 0.00012 22.5 0.0 0.00036 20.9 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cytochrom_CIII PF02085.16 PSC69821.1 - 0.21 12.0 4.7 1.5 9.2 0.2 2.3 2 0 0 2 2 2 0 Class III cytochrome C family JmjC PF02373.22 PSC69822.1 - 0.00012 22.5 0.0 0.00036 20.9 0.0 1.8 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cytochrom_CIII PF02085.16 PSC69822.1 - 0.21 12.0 4.7 1.5 9.2 0.2 2.3 2 0 0 2 2 2 0 Class III cytochrome C family RNA_pol_L_2 PF13656.6 PSC69823.1 - 3e-16 58.9 0.0 7.6e-16 57.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 PSC69823.1 - 5.6e-07 28.9 0.0 1.3e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Tweety PF04906.13 PSC69823.1 - 2.5e-05 23.1 1.5 0.096 11.3 0.0 2.5 2 0 0 2 2 2 2 Tweety DctQ PF04290.12 PSC69823.1 - 0.18 11.8 0.1 0.18 11.8 0.1 3.8 3 1 1 4 4 4 0 Tripartite ATP-independent periplasmic transporters, DctQ component DUF2207 PF09972.9 PSC69823.1 - 0.28 9.9 0.1 2.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Pex24p PF06398.11 PSC69823.1 - 0.41 9.6 2.5 0.68 8.9 2.5 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin EphA2_TM PF14575.6 PSC69823.1 - 2.5 9.0 0.0 2.5 9.0 0.0 2.9 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain Lar_restr_allev PF14354.6 PSC69824.1 - 0.0052 17.1 0.5 0.012 16.0 0.5 1.5 1 0 0 1 1 1 1 Restriction alleviation protein Lar zf-ribbon_3 PF13248.6 PSC69824.1 - 0.028 13.8 2.4 4.5 6.8 0.4 2.7 2 0 0 2 2 2 0 zinc-ribbon domain TerY_C PF15616.6 PSC69824.1 - 0.028 14.5 0.1 0.049 13.8 0.1 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain zf-DNA_Pol PF08996.10 PSC69824.1 - 0.057 13.2 0.2 0.15 11.8 0.1 1.6 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger Terminase_GpA PF05876.12 PSC69824.1 - 0.074 11.6 0.0 0.098 11.2 0.0 1.1 1 0 0 1 1 1 0 Phage terminase large subunit (GpA) zf-Sec23_Sec24 PF04810.15 PSC69824.1 - 0.14 12.3 2.6 3.5 7.8 0.0 3.2 3 0 0 3 3 3 0 Sec23/Sec24 zinc finger OrfB_Zn_ribbon PF07282.11 PSC69824.1 - 0.18 11.8 0.5 0.33 10.9 0.5 1.4 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.6 PSC69824.1 - 0.29 10.9 3.2 1.8 8.4 0.5 2.6 2 0 0 2 2 2 0 zinc-ribbon domain TFIIS_C PF01096.18 PSC69824.1 - 1.4 8.8 3.2 7.5 6.5 3.2 2.1 1 1 0 1 1 1 0 Transcription factor S-II (TFIIS) VWA_2 PF13519.6 PSC69825.1 - 4.7e-09 36.9 0.0 2.3e-08 34.7 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain RRM_1 PF00076.22 PSC69825.1 - 2e-05 24.3 0.0 4.4e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) VWA_CoxE PF05762.14 PSC69825.1 - 0.00035 20.0 0.0 0.00093 18.6 0.0 1.7 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein DUF913 PF06025.12 PSC69825.1 - 0.05 12.6 4.3 0.097 11.6 4.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Ndc1_Nup PF09531.10 PSC69825.1 - 0.19 10.4 7.5 0.28 9.8 7.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SRP-alpha_N PF04086.13 PSC69825.1 - 0.66 9.8 14.5 1.1 9.1 14.5 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Presenilin PF01080.17 PSC69825.1 - 5.7 5.6 15.5 8.7 5.0 15.5 1.1 1 0 0 1 1 1 0 Presenilin Borrelia_P83 PF05262.11 PSC69825.1 - 5.9 5.3 12.9 8.2 4.8 12.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein Amino_oxidase PF01593.24 PSC69826.1 - 6.2e-59 200.5 7.6 1.5e-56 192.6 4.6 3.1 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PSC69826.1 - 2.3e-06 27.7 0.6 7.7e-06 26.0 0.1 2.2 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain TFIIA PF03153.13 PSC69826.1 - 0.00028 21.0 24.8 0.00042 20.4 24.8 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 PSC69826.1 - 0.17 10.5 7.6 0.24 10.0 7.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Med15 PF09606.10 PSC69826.1 - 2.4 6.7 36.1 3.3 6.3 36.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.9 PSC69826.1 - 4.2 5.5 20.4 6.1 5.0 20.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SARAF PF06682.12 PSC69826.1 - 4.6 6.8 14.1 7.7 6.1 14.1 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SLC12 PF03522.15 PSC69826.1 - 7.7 5.4 6.4 13 4.7 6.4 1.3 1 0 0 1 1 1 0 Solute carrier family 12 PPR_2 PF13041.6 PSC69827.1 - 3.8e-60 199.9 0.0 2.7e-10 40.3 0.0 10.3 5 2 5 11 11 11 9 PPR repeat family PPR_3 PF13812.6 PSC69827.1 - 5.9e-52 173.6 0.0 2.9e-09 36.9 0.0 8.1 5 2 3 8 8 8 7 Pentatricopeptide repeat domain PPR_1 PF12854.7 PSC69827.1 - 1.9e-51 171.4 0.0 4.3e-05 23.1 0.0 12.7 14 0 0 14 14 14 9 PPR repeat DDRGK PF09756.9 PSC69827.1 - 1.4e-45 155.2 8.2 2.4e-45 154.5 8.2 1.3 1 0 0 1 1 1 1 DDRGK domain PPR PF01535.20 PSC69827.1 - 2.3e-42 140.3 0.0 0.00088 19.4 0.0 13.2 13 0 0 13 13 13 8 PPR repeat PPR_long PF17177.4 PSC69827.1 - 1.5e-16 60.4 8.1 1.5e-05 24.4 0.0 5.0 2 2 4 6 6 6 5 Pentacotripeptide-repeat region of PRORP MRP-S27 PF10037.9 PSC69827.1 - 0.0042 16.0 0.0 0.17 10.7 0.0 2.9 2 1 1 3 3 3 1 Mitochondrial 28S ribosomal protein S27 DUF2183 PF09949.9 PSC69827.1 - 0.0071 16.7 0.0 0.02 15.2 0.0 1.7 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2183) FeoC PF09012.10 PSC69827.1 - 0.019 15.0 0.0 1.2 9.2 0.0 2.5 2 0 0 2 2 2 0 FeoC like transcriptional regulator Spt5_N PF11942.8 PSC69827.1 - 0.56 11.2 19.4 1.8 9.6 19.4 1.9 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal EcoR124_C PF12008.8 PSC69827.1 - 0.68 9.5 1.8 1.2 8.8 1.8 1.2 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal DUF1929 PF09118.11 PSC69828.1 - 1.7e-07 31.5 0.0 1.8e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) bZIP_2 PF07716.15 PSC69829.1 - 1.6 8.9 10.0 4.3 7.5 10.0 1.7 1 0 0 1 1 1 0 Basic region leucine zipper FliJ PF02050.16 PSC69829.1 - 1.7 8.9 16.0 0.2 11.9 10.0 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein CS PF04969.16 PSC69830.1 - 2.4e-13 50.9 0.0 3.6e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 CS domain zf-MYND PF01753.18 PSC69830.1 - 3.9e-09 36.4 12.6 3.9e-09 36.4 12.6 2.4 2 0 0 2 2 2 1 MYND finger Chorion_S16 PF05836.12 PSC69830.1 - 0.021 15.0 0.7 0.049 13.9 0.7 1.6 1 0 0 1 1 1 0 Chorion protein S16 zf-HIT PF04438.16 PSC69830.1 - 0.022 14.6 4.5 0.052 13.4 4.5 1.6 1 0 0 1 1 1 0 HIT zinc finger zf-C6H2 PF15801.5 PSC69830.1 - 0.17 12.2 10.6 0.43 10.9 10.6 1.7 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding bVLRF1 PF18826.1 PSC69831.1 - 1.5e-50 170.9 0.5 2.9e-50 170.0 0.0 1.7 2 0 0 2 2 2 1 bacteroidetes VLRF1 release factor DUF1682 PF07946.14 PSC69831.1 - 0.24 10.6 7.1 0.35 10.0 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Draxin PF15550.6 PSC69831.1 - 0.4 10.5 3.9 0.78 9.6 3.9 1.4 1 0 0 1 1 1 0 Draxin DUF4776 PF16003.5 PSC69831.1 - 0.51 9.3 3.0 0.71 8.8 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) DUF3381 PF11861.8 PSC69831.1 - 1.1 9.0 10.2 1.8 8.4 10.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) Asp-B-Hydro_N PF05279.11 PSC69831.1 - 6 6.9 13.4 9.6 6.2 13.4 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region STIL_N PF15253.6 PSC69832.1 - 1.3e-21 77.0 0.3 2.1e-21 76.3 0.0 1.4 2 0 0 2 2 2 1 SCL-interrupting locus protein N-terminus UMP1 PF05348.11 PSC69832.1 - 1.8e-19 70.1 0.0 1.8e-19 70.1 0.0 2.4 3 0 0 3 3 3 1 Proteasome maturation factor UMP1 TFIIA PF03153.13 PSC69832.1 - 0.0019 18.3 14.6 0.0027 17.8 14.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 PSC69832.1 - 0.026 14.2 14.1 0.04 13.5 14.1 1.2 1 0 0 1 1 1 0 Spt20 family EIF4E-T PF10477.9 PSC69832.1 - 0.37 9.6 11.0 0.51 9.1 11.0 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Rrn6 PF10214.9 PSC69832.1 - 0.69 8.3 6.6 0.9 8.0 6.6 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor TonB_N PF16031.5 PSC69832.1 - 8 7.0 14.6 16 6.0 0.3 2.7 2 0 0 2 2 2 0 TonB polyproline region CDO_I PF05995.12 PSC69833.1 - 1.7e-25 89.3 0.1 2.3e-24 85.6 0.1 2.0 1 1 0 1 1 1 1 Cysteine dioxygenase type I BUD22 PF09073.10 PSC69834.1 - 1.1e-34 120.5 74.0 2.3e-20 73.4 62.0 4.2 2 1 0 2 2 2 2 BUD22 ABC2_membrane PF01061.24 PSC69835.1 - 1.8e-70 236.6 64.2 5.5e-43 146.8 30.1 3.5 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 PSC69835.1 - 1.1e-38 132.8 0.0 9.1e-20 71.6 0.0 3.0 2 1 0 2 2 2 2 ABC transporter MBOAT PF03062.19 PSC69835.1 - 7.5e-38 130.8 1.7 7.5e-38 130.8 1.7 2.1 2 0 0 2 2 1 1 MBOAT, membrane-bound O-acyltransferase family Ephrin_rec_like PF07699.13 PSC69835.1 - 3.8e-34 116.2 148.0 2.2e-06 27.3 11.3 18.7 9 4 9 18 18 18 12 Putative ephrin-receptor like NCD3G PF07562.14 PSC69835.1 - 1.3e-08 34.7 96.4 0.29 11.1 1.6 12.9 8 3 3 13 13 13 7 Nine Cysteines Domain of family 3 GPCR PDR_CDR PF06422.12 PSC69835.1 - 1.1e-07 31.6 0.9 0.0021 17.9 0.2 3.1 2 0 0 2 2 2 2 CDR ABC transporter AAA_16 PF13191.6 PSC69835.1 - 8.9e-07 29.4 2.0 0.0082 16.5 0.5 3.0 2 1 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 PSC69835.1 - 3.4e-06 27.1 0.0 1.3 8.8 0.0 3.8 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_25 PF13481.6 PSC69835.1 - 4.7e-06 26.3 0.1 0.0058 16.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 PSC69835.1 - 1.6e-05 24.5 0.5 0.19 11.1 0.1 3.4 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PSC69835.1 - 1.7e-05 24.5 2.8 0.043 13.6 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 PSC69835.1 - 8.7e-05 22.7 0.1 0.38 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 PSC69835.1 - 0.00049 19.3 56.5 0.0018 17.4 27.3 2.6 2 1 0 2 2 2 2 ABC-2 family transporter protein AAA_22 PF13401.6 PSC69835.1 - 0.00062 20.1 0.1 0.56 10.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain PDR_assoc PF08370.11 PSC69835.1 - 0.00075 19.2 2.9 0.033 13.9 0.1 2.9 2 0 0 2 2 2 1 Plant PDR ABC transporter associated RsgA_GTPase PF03193.16 PSC69835.1 - 0.0022 17.9 2.5 0.38 10.7 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 PSC69835.1 - 0.0071 16.9 0.5 0.17 12.3 0.1 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PSC69835.1 - 0.0093 15.7 0.2 4.9 6.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PSC69835.1 - 0.031 14.6 0.2 16 5.8 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 PSC69835.1 - 0.096 13.2 0.1 1.5 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 PSC69835.1 - 0.11 12.4 2.1 1.7 8.5 0.0 2.5 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 PSC69835.1 - 0.14 12.6 1.1 5.5 7.4 0.0 3.5 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 PSC69835.1 - 0.18 10.9 0.1 8.4 5.4 0.1 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_5 PF07728.14 PSC69835.1 - 0.41 10.6 1.1 0.57 10.2 0.1 1.8 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) cobW PF02492.19 PSC69835.1 - 1.3 8.6 4.1 11 5.6 0.6 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TNFR_c6 PF00020.18 PSC69835.1 - 1.5 9.3 103.8 0.26 11.7 3.2 15.5 10 3 3 13 13 11 0 TNFR/NGFR cysteine-rich region Ribosomal_L34e PF01199.18 PSC69836.1 - 4e-37 126.4 2.1 1.8e-36 124.3 2.1 2.3 1 0 0 1 1 1 1 Ribosomal protein L34e CRAL_TRIO_2 PF13716.6 PSC69836.1 - 6.3e-15 55.5 0.0 1.3e-14 54.5 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 PSC69836.1 - 0.0077 16.0 0.1 0.68 9.6 0.1 2.2 2 0 0 2 2 2 2 CRAL/TRIO domain PDDEXK_6 PF04720.12 PSC69837.1 - 2.8e-17 63.4 0.0 5.3e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 PDDEXK-like family of unknown function Hexapep PF00132.24 PSC69839.1 - 3.6e-11 42.3 5.5 9.9e-05 21.9 0.1 4.4 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) WD40 PF00400.32 PSC69839.1 - 2.3e-05 25.1 0.2 0.11 13.4 0.0 3.6 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC69839.1 - 0.00082 19.6 0.0 0.014 15.7 0.0 2.6 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Hexapep_2 PF14602.6 PSC69839.1 - 0.0016 18.2 7.3 0.016 15.0 0.1 3.8 2 2 2 4 4 4 2 Hexapeptide repeat of succinyl-transferase Aa_trans PF01490.18 PSC69840.1 - 3.4e-37 128.1 14.6 5.4e-37 127.5 14.6 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NmrA PF05368.13 PSC69840.1 - 2.5e-17 63.2 0.1 2.5e-17 63.2 0.1 3.4 3 0 0 3 3 3 1 NmrA-like family Epimerase PF01370.21 PSC69840.1 - 1.3e-11 44.4 0.0 4.1e-11 42.8 0.0 1.9 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PSC69840.1 - 3.2e-07 29.7 0.1 6.6e-07 28.6 0.1 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 PSC69840.1 - 0.00016 21.2 0.0 0.00016 21.2 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 PSC69840.1 - 0.0067 16.9 0.2 0.0067 16.9 0.2 3.2 4 0 0 4 4 4 1 Semialdehyde dehydrogenase, NAD binding domain Mur_ligase_C PF02875.21 PSC69840.1 - 1.3 9.3 5.2 0.66 10.3 1.0 2.7 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain Aa_trans PF01490.18 PSC69841.1 - 3.4e-37 128.1 14.6 5.4e-37 127.5 14.6 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein NmrA PF05368.13 PSC69841.1 - 2.5e-17 63.2 0.1 2.5e-17 63.2 0.1 3.4 3 0 0 3 3 3 1 NmrA-like family Epimerase PF01370.21 PSC69841.1 - 1.3e-11 44.4 0.0 4.1e-11 42.8 0.0 1.9 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PSC69841.1 - 3.2e-07 29.7 0.1 6.6e-07 28.6 0.1 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 PSC69841.1 - 0.00016 21.2 0.0 0.00016 21.2 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Semialdhyde_dh PF01118.24 PSC69841.1 - 0.0067 16.9 0.2 0.0067 16.9 0.2 3.2 4 0 0 4 4 4 1 Semialdehyde dehydrogenase, NAD binding domain Mur_ligase_C PF02875.21 PSC69841.1 - 1.4 9.3 5.2 0.66 10.3 1.0 2.7 2 0 0 2 2 2 0 Mur ligase family, glutamate ligase domain RCC1 PF00415.18 PSC69842.1 - 9.6e-76 250.3 21.4 5.1e-12 46.2 0.0 8.3 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PSC69842.1 - 7.6e-41 137.1 43.3 1.8e-08 34.0 0.3 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat F-box-like PF12937.7 PSC69842.1 - 0.015 15.2 0.0 0.037 13.9 0.0 1.6 1 0 0 1 1 1 0 F-box-like Elongin_A PF06881.11 PSC69842.1 - 0.087 13.4 0.0 0.15 12.6 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Kelch_2 PF07646.15 PSC69842.1 - 0.13 12.3 1.2 14 5.8 0.0 3.4 3 0 0 3 3 3 0 Kelch motif DAO PF01266.24 PSC69844.1 - 5.2e-26 92.1 6.6 8.5e-25 88.1 6.7 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase Rieske PF00355.26 PSC69844.1 - 2.7e-15 56.1 1.4 2.7e-15 56.1 1.4 2.7 3 0 0 3 3 3 1 Rieske [2Fe-2S] domain PHD PF00628.29 PSC69844.1 - 3.6e-07 30.0 10.8 4.2e-05 23.3 10.9 2.7 2 0 0 2 2 2 1 PHD-finger Thi4 PF01946.17 PSC69844.1 - 9.6e-05 21.7 0.1 0.0002 20.7 0.1 1.4 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.6 PSC69844.1 - 0.00014 22.0 0.7 0.00084 19.5 0.1 2.8 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 PSC69844.1 - 0.00016 20.9 0.6 0.00038 19.7 0.6 1.6 1 0 0 1 1 1 1 FAD binding domain Jas PF16135.5 PSC69844.1 - 0.00026 21.1 3.0 0.00037 20.6 0.0 2.9 3 0 0 3 3 3 1 TPL-binding domain in jasmonate signalling Pyr_redox_2 PF07992.14 PSC69844.1 - 0.00098 18.4 0.0 0.003 16.8 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase PHD_2 PF13831.6 PSC69844.1 - 0.011 15.2 3.5 0.039 13.5 3.5 2.0 1 0 0 1 1 1 0 PHD-finger GIDA PF01134.22 PSC69844.1 - 0.012 14.8 0.0 0.019 14.1 0.0 1.3 1 0 0 1 1 1 0 Glucose inhibited division protein A HI0933_like PF03486.14 PSC69844.1 - 0.024 13.4 0.1 0.051 12.3 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein Lycopene_cycl PF05834.12 PSC69844.1 - 0.085 11.9 0.1 0.16 11.0 0.1 1.5 1 0 0 1 1 1 0 Lycopene cyclase protein Acetyltransf_1 PF00583.25 PSC69844.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family WHAMM-JMY_N PF15920.5 PSC69844.1 - 0.22 11.4 1.5 0.45 10.4 0.6 2.0 1 1 1 2 2 2 0 N-terminal of Junction-mediating and WASP homolog-associated PEP_mutase PF13714.6 PSC69845.1 - 3.3e-44 151.1 0.4 3.3e-44 151.1 0.4 1.6 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 PSC69845.1 - 1.7e-11 43.4 0.1 2.4e-11 42.8 0.1 1.2 1 0 0 1 1 1 1 Isocitrate lyase family DUF2368 PF10166.9 PSC69847.1 - 0.12 12.0 1.5 0.31 10.7 1.5 1.6 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) TMEM43 PF07787.12 PSC69847.1 - 0.85 9.0 4.6 3.3 7.0 0.2 2.4 2 0 0 2 2 2 0 Transmembrane protein 43 DUF2956 PF11169.8 PSC69847.1 - 0.97 9.7 4.1 15 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) TMEM52 PF14979.6 PSC69847.1 - 1.7 8.6 6.3 13 5.7 0.8 2.7 2 0 0 2 2 2 0 Transmembrane 52 DUF2408 PF10303.9 PSC69848.1 - 7.6e-28 97.7 0.0 9.3e-09 36.0 0.0 3.2 1 1 2 3 3 3 3 Protein of unknown function (DUF2408) V-SNARE PF05008.15 PSC69848.1 - 0.003 17.9 1.0 0.063 13.7 0.0 3.1 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus DUF1664 PF07889.12 PSC69848.1 - 0.0032 17.5 2.4 6.7 6.8 0.1 3.8 4 0 0 4 4 4 2 Protein of unknown function (DUF1664) KxDL PF10241.9 PSC69848.1 - 0.014 15.7 1.2 3.5 8.0 0.0 3.6 4 0 0 4 4 4 0 Uncharacterized conserved protein DUF948 PF06103.11 PSC69848.1 - 0.072 13.4 0.5 13 6.1 0.1 3.5 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 PSC69848.1 - 0.11 12.6 3.3 1.9 8.5 0.2 3.3 4 0 0 4 4 4 0 Laminin Domain II BLOC1S3 PF15753.5 PSC69848.1 - 0.14 12.3 0.3 14 5.7 0.1 2.7 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF4763 PF15960.5 PSC69848.1 - 0.28 10.5 4.9 0.22 10.8 0.4 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4763) DUF2076 PF09849.9 PSC69850.1 - 0.098 12.7 3.8 0.22 11.5 3.8 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Adeno_E3_CR2 PF02439.15 PSC69850.1 - 0.16 11.8 1.2 0.28 11.0 1.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DAP10 PF07213.11 PSC69850.1 - 0.2 11.6 1.4 0.48 10.4 1.4 1.6 1 0 0 1 1 1 0 DAP10 membrane protein SOUL PF04832.12 PSC69851.1 - 1.1e-16 61.5 0.0 1.9e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 SOUL heme-binding protein PAT1 PF09770.9 PSC69852.1 - 0.0063 14.8 10.3 0.0081 14.5 10.3 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF1455 PF07306.11 PSC69852.1 - 9.1 6.3 11.6 0.31 11.0 3.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1455) F-box PF00646.33 PSC69855.1 - 9.8e-07 28.5 0.4 4.3e-06 26.5 0.2 2.2 2 0 0 2 2 2 1 F-box domain LRR_4 PF12799.7 PSC69855.1 - 1.8e-06 28.2 0.8 0.77 10.3 0.5 4.7 3 1 2 5 5 5 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PSC69855.1 - 0.0004 20.2 5.7 0.072 13.2 0.0 5.5 6 0 0 6 6 6 1 Leucine Rich repeat F-box-like PF12937.7 PSC69855.1 - 0.0042 16.9 0.1 0.0099 15.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 PSC69855.1 - 0.085 12.6 4.6 2.4 8.0 0.9 4.0 3 1 0 3 3 3 0 Leucine rich repeat SMC_Nse1 PF07574.13 PSC69856.1 - 2.9e-31 108.9 0.0 3.4e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Nse1 non-SMC component of SMC5-6 complex RskA PF10099.9 PSC69856.1 - 1.4 9.1 7.4 0.48 10.7 1.9 2.0 2 0 0 2 2 2 0 Anti-sigma-K factor rskA K_channel_TID PF07941.11 PSC69856.1 - 4.9 7.7 24.7 0.63 10.5 19.0 2.4 2 1 1 3 3 3 0 Potassium channel Kv1.4 tandem inactivation domain Amino_oxidase PF01593.24 PSC69857.1 - 5.8e-19 68.7 0.4 9.2e-18 64.8 0.4 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PSC69857.1 - 2e-13 50.4 0.6 2e-13 50.4 0.6 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PSC69857.1 - 1.5e-11 44.5 4.2 3.9e-05 23.4 0.3 2.5 2 1 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PSC69857.1 - 8.2e-10 38.3 7.5 0.00012 21.3 0.7 2.6 3 0 0 3 3 3 2 FAD binding domain FAD_oxidored PF12831.7 PSC69857.1 - 2.3e-05 23.9 1.4 0.0049 16.3 0.9 2.1 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 PSC69857.1 - 2.9e-05 23.5 0.1 6.3e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox PF00070.27 PSC69857.1 - 6.9e-05 23.3 1.3 0.022 15.3 0.2 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GMC_oxred_N PF00732.19 PSC69857.1 - 0.0002 20.9 0.0 0.00033 20.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase HI0933_like PF03486.14 PSC69857.1 - 0.0002 20.2 0.2 0.13 11.0 0.2 2.2 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.19 PSC69857.1 - 0.00031 20.1 0.4 0.00051 19.4 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 PSC69857.1 - 0.0024 17.2 0.9 0.0043 16.3 0.0 1.9 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase MCRA PF06100.11 PSC69857.1 - 0.011 14.5 0.3 0.018 13.9 0.3 1.3 1 0 0 1 1 1 0 MCRA family GDI PF00996.18 PSC69857.1 - 0.019 13.5 0.0 0.078 11.5 0.0 1.8 2 0 0 2 2 2 0 GDP dissociation inhibitor Trp_halogenase PF04820.14 PSC69857.1 - 0.024 13.5 0.1 0.13 11.1 0.1 1.9 2 0 0 2 2 2 0 Tryptophan halogenase UPF0227 PF05728.12 PSC69857.1 - 0.16 11.9 0.0 0.57 10.1 0.0 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0227) GIDA PF01134.22 PSC69857.1 - 0.27 10.2 2.5 0.35 9.9 1.2 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Trypan_PARP PF05887.11 PSC69858.1 - 0.054 13.5 6.7 0.11 12.5 6.7 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DEC-1_N PF04625.13 PSC69858.1 - 0.84 8.6 6.9 1.2 8.1 6.9 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region PI-PLC-C1 PF16670.5 PSC69859.1 - 2.3e-55 188.0 0.0 1.8e-39 135.7 0.0 3.2 2 2 0 2 2 2 2 Phosphoinositide phospholipase C, Ca2+-dependent rve PF00665.26 PSC69859.1 - 2e-18 66.7 0.0 4.1e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC69859.1 - 0.015 15.1 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain PI-PLC-X PF00388.19 PSC69859.1 - 0.12 11.9 0.0 0.62 9.6 0.0 1.9 2 0 0 2 2 2 0 Phosphatidylinositol-specific phospholipase C, X domain Peptidase_C26 PF07722.13 PSC69860.1 - 9.4e-16 58.2 0.0 3e-15 56.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 PSC69860.1 - 1e-07 31.9 0.0 1.9e-07 31.0 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I stn_TNFRSF12A PF12191.8 PSC69860.1 - 0.045 14.0 0.0 0.32 11.2 0.1 2.1 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain CobN-Mg_chel PF02514.16 PSC69860.1 - 0.23 9.1 0.0 0.34 8.6 0.0 1.1 1 0 0 1 1 1 0 CobN/Magnesium Chelatase SOG2 PF10428.9 PSC69861.1 - 8.4 5.5 9.1 10 5.2 9.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein SOG2 PF10428.9 PSC69862.1 - 8.7 5.4 9.1 11 5.1 9.1 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Frataxin_Cyay PF01491.16 PSC69863.1 - 0.052 13.6 0.0 0.19 11.8 0.0 1.8 1 1 0 1 1 1 0 Frataxin-like domain GSHPx PF00255.19 PSC69864.1 - 3.4e-38 129.5 0.0 6.2e-38 128.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 PSC69864.1 - 0.00042 20.2 0.0 0.0013 18.6 0.0 1.8 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 PSC69864.1 - 0.0012 18.5 0.0 0.0022 17.7 0.0 1.3 1 0 0 1 1 1 1 Redoxin DUF4044 PF13253.6 PSC69864.1 - 0.014 14.9 0.6 0.023 14.2 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) DUF4407 PF14362.6 PSC69864.1 - 0.35 10.2 11.9 0.53 9.6 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Methyltransf_10 PF05971.12 PSC69865.1 - 3.4e-63 213.8 0.4 9.2e-33 113.8 0.0 4.0 3 1 0 3 3 3 3 RNA methyltransferase MTS PF05175.14 PSC69865.1 - 1.1e-05 25.1 0.0 0.042 13.4 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase small domain Methyltransf_11 PF08241.12 PSC69865.1 - 0.0018 18.9 0.0 0.0074 16.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC69865.1 - 0.012 16.4 0.1 0.069 13.9 0.1 2.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 PSC69865.1 - 0.034 14.9 0.0 0.15 12.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 PSC69865.1 - 0.036 13.9 0.0 0.11 12.3 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain EPSP_synthase PF00275.20 PSC69867.1 - 1.3e-132 442.5 0.0 1.7e-132 442.0 0.0 1.2 1 0 0 1 1 1 1 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) Pkinase PF00069.25 PSC69867.1 - 6.1e-46 156.9 0.0 9e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC69867.1 - 5.5e-43 147.1 0.0 1.1e-42 146.1 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PSC69867.1 - 0.0022 17.4 0.3 0.0052 16.2 0.1 1.7 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family PH_12 PF16457.5 PSC69867.1 - 0.15 12.6 0.0 0.32 11.5 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain APH PF01636.23 PSC69867.1 - 7 6.5 14.6 0.3 11.0 0.1 4.4 3 1 1 4 4 4 0 Phosphotransferase enzyme family Amino_oxidase PF01593.24 PSC69868.1 - 3.5e-10 39.8 0.0 2.9e-09 36.7 0.0 2.0 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PSC69868.1 - 7.9e-08 32.4 0.0 1.7e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 PSC69868.1 - 0.003 16.7 0.1 0.0043 16.2 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 PSC69868.1 - 0.0075 15.6 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 PSC69868.1 - 0.0097 15.3 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 PSC69868.1 - 0.029 13.6 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PSC69868.1 - 0.071 12.3 0.0 0.17 11.1 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PSC69868.1 - 0.082 12.5 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase SNAP PF14938.6 PSC69869.1 - 9.5e-18 64.6 14.8 1.2e-17 64.3 14.8 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_8 PF13181.6 PSC69869.1 - 0.00088 19.3 7.6 0.037 14.2 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 PSC69869.1 - 0.00091 19.0 5.5 0.19 11.6 0.3 4.7 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 PSC69869.1 - 0.002 18.3 19.8 0.078 13.3 6.9 4.9 2 1 3 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 PSC69869.1 - 0.0059 16.6 18.8 0.17 12.1 1.3 5.7 4 2 2 6 6 6 1 Tetratricopeptide repeat TPR_7 PF13176.6 PSC69869.1 - 0.025 14.6 12.1 3 8.1 0.5 5.4 3 2 2 5 5 5 0 Tetratricopeptide repeat NSF PF02071.20 PSC69869.1 - 0.047 14.4 13.8 13 7.1 1.9 6.6 6 1 0 7 7 7 0 Aromatic-di-Alanine (AdAR) repeat NmrA PF05368.13 PSC69870.1 - 1.6e-39 135.8 0.0 2.4e-39 135.3 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 PSC69870.1 - 1.5e-20 73.8 0.1 2.4e-20 73.2 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding LRR_4 PF12799.7 PSC69870.1 - 1.1e-10 41.6 0.1 2.3e-05 24.6 0.0 3.9 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC69870.1 - 2.4e-06 27.2 5.1 0.00042 20.0 0.0 4.7 3 1 2 5 5 5 2 Leucine rich repeat 3Beta_HSD PF01073.19 PSC69870.1 - 0.0013 17.8 0.0 0.0017 17.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family LRR_1 PF00560.33 PSC69870.1 - 0.0019 18.5 2.1 28 5.8 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat Semialdhyde_dh PF01118.24 PSC69870.1 - 0.0022 18.4 0.4 0.0089 16.5 0.0 2.1 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain LRR_6 PF13516.6 PSC69870.1 - 0.03 14.3 1.7 2.2 8.6 0.0 4.2 4 0 0 4 4 4 0 Leucine Rich repeat F-box-like PF12937.7 PSC69870.1 - 3.9 7.4 6.3 1 9.3 0.7 2.7 3 0 0 3 3 3 0 F-box-like POR_N PF01855.19 PSC69871.1 - 1.2e-76 257.4 3.3 2.2e-76 256.6 3.3 1.4 1 0 0 1 1 1 1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg POR PF01558.18 PSC69871.1 - 1.9e-29 103.0 0.2 3.6e-29 102.1 0.2 1.5 1 0 0 1 1 1 1 Pyruvate ferredoxin/flavodoxin oxidoreductase PFOR_II PF17147.4 PSC69871.1 - 5.1e-14 52.4 0.1 1.7e-13 50.7 0.1 2.0 1 0 0 1 1 1 1 Pyruvate:ferredoxin oxidoreductase core domain II Acetyltransf_1 PF00583.25 PSC69871.1 - 5.1e-14 52.5 0.0 1e-13 51.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family EKR PF10371.9 PSC69871.1 - 5.9e-14 51.6 0.1 1.5e-13 50.3 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function Fer4_16 PF13484.6 PSC69871.1 - 1.9e-09 38.3 6.6 0.00071 20.5 0.3 2.6 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Acetyltransf_10 PF13673.7 PSC69871.1 - 6.8e-09 35.7 0.0 1.5e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain TPP_enzyme_C PF02775.21 PSC69871.1 - 1.5e-08 34.6 0.0 4.2e-08 33.1 0.0 1.8 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Fer4_7 PF12838.7 PSC69871.1 - 1.7e-08 34.9 7.3 4.1e-08 33.7 7.3 1.7 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4 PF00037.27 PSC69871.1 - 2.2e-08 33.6 19.8 1.5e-05 24.6 1.8 3.1 3 0 0 3 3 3 2 4Fe-4S binding domain Acetyltransf_7 PF13508.7 PSC69871.1 - 3.3e-08 33.8 0.0 7.5e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC69871.1 - 9.1e-08 32.0 0.0 3.8e-07 30.0 0.0 2.0 2 0 0 2 2 1 1 FR47-like protein Fer4_21 PF14697.6 PSC69871.1 - 1.5e-07 31.4 6.0 0.00079 19.5 0.4 2.5 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 PSC69871.1 - 2e-06 27.9 9.9 4.4e-05 23.6 10.0 2.4 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.7 PSC69871.1 - 2.2e-05 24.3 21.2 0.00021 21.2 4.0 2.7 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_10 PF13237.6 PSC69871.1 - 0.00014 21.9 10.9 0.00017 21.6 8.9 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Transketolase_C PF02780.20 PSC69871.1 - 0.00095 19.1 0.1 0.0034 17.3 0.1 1.9 1 0 0 1 1 1 1 Transketolase, C-terminal domain Fer4_17 PF13534.6 PSC69871.1 - 0.0014 19.1 9.5 0.0043 17.6 8.5 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 PSC69871.1 - 0.0015 18.5 21.9 0.0056 16.7 3.5 3.0 3 0 0 3 3 2 2 4Fe-4S binding domain Acetyltransf_9 PF13527.7 PSC69871.1 - 0.0074 16.4 0.0 0.016 15.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fer4_18 PF13746.6 PSC69871.1 - 0.056 13.6 8.2 0.19 11.9 6.4 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain Acetyltransf_13 PF13880.6 PSC69871.1 - 0.098 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase Fer4_8 PF13183.6 PSC69871.1 - 0.16 12.4 11.7 0.51 10.8 11.0 2.2 1 1 2 3 3 3 0 4Fe-4S dicluster domain DUF3043 PF11241.8 PSC69871.1 - 0.49 10.4 4.4 1.2 9.2 4.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Fer4_4 PF12800.7 PSC69871.1 - 0.95 10.1 10.0 0.46 11.1 1.8 2.7 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_3 PF12798.7 PSC69871.1 - 3.6 8.7 19.5 0.3 12.1 5.6 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain AhpC-TSA PF00578.21 PSC69873.1 - 8.8e-40 135.5 0.0 1.3e-39 134.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PSC69873.1 - 7.8e-18 64.6 0.0 1e-17 64.2 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 PSC69873.1 - 5.6e-11 42.1 0.1 1.2e-10 41.0 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 PSC69873.1 - 0.013 15.4 0.0 0.059 13.3 0.0 1.9 2 0 0 2 2 2 0 SCO1/SenC Acetyltransf_1 PF00583.25 PSC69874.1 - 1.2e-11 44.8 0.0 1.5e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PSC69874.1 - 1.7e-08 34.8 0.0 2.9e-08 34.0 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PSC69874.1 - 1.5e-07 31.4 0.0 1.8e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC69874.1 - 7.4e-05 22.6 0.0 0.00013 21.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 PSC69874.1 - 0.0016 18.5 0.0 0.0019 18.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 PSC69874.1 - 0.0019 17.9 0.0 0.0025 17.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 PSC69874.1 - 0.016 15.9 0.1 0.02 15.6 0.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PSC69874.1 - 0.042 14.0 0.2 0.085 13.0 0.1 1.6 1 1 0 1 1 1 0 GCN5-related N-acetyl-transferase Spc7 PF08317.11 PSC69875.1 - 0.0059 15.5 16.8 0.0059 15.5 16.8 7.4 2 1 6 8 8 8 5 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 PSC69875.1 - 0.01 15.8 2.1 0.01 15.8 2.1 7.8 2 1 4 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 PSC69875.1 - 0.012 15.8 21.2 0.012 15.8 21.2 6.9 2 1 4 6 6 6 0 Autophagy protein 16 (ATG16) Baculo_PEP_C PF04513.12 PSC69875.1 - 1.8 8.6 36.1 0.04 14.0 2.6 6.6 4 1 4 8 8 8 0 Baculovirus polyhedron envelope protein, PEP, C terminus Ribosomal_L5 PF00281.19 PSC69876.1 - 2.4e-21 75.8 0.0 5.1e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 PSC69876.1 - 2.9e-21 75.4 0.0 4.4e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus SANT_DAMP1_like PF16282.5 PSC69878.1 - 5.9e-08 32.8 1.3 0.0015 18.7 0.2 2.5 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 DUF3138 PF11336.8 PSC69878.1 - 3.1 6.3 6.4 4.7 5.7 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Arm PF00514.23 PSC69879.1 - 4.7e-67 220.2 59.1 1.4e-09 37.6 0.3 15.9 15 0 0 15 15 15 12 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 PSC69879.1 - 3.1e-10 40.3 95.0 0.0053 17.2 0.9 12.8 11 2 1 12 12 12 7 HEAT-like repeat Atx10homo_assoc PF09759.9 PSC69879.1 - 3.7e-08 33.3 3.0 0.23 11.5 0.1 6.3 4 2 2 8 8 8 2 Spinocerebellar ataxia type 10 protein domain Arm_2 PF04826.13 PSC69879.1 - 1.6e-05 24.5 0.2 0.21 11.0 0.0 3.6 2 2 1 3 3 3 2 Armadillo-like HEAT_2 PF13646.6 PSC69879.1 - 0.00025 21.4 4.5 0.00025 21.4 4.5 9.6 4 2 7 11 11 11 5 HEAT repeats KAP PF05804.12 PSC69879.1 - 0.0038 15.4 0.0 0.97 7.5 0.0 3.0 3 0 0 3 3 3 2 Kinesin-associated protein (KAP) BAF250_C PF12031.8 PSC69879.1 - 0.026 13.8 0.8 0.19 11.0 0.1 2.5 2 0 0 2 2 2 0 SWI/SNF-like complex subunit BAF250/Osa AP_endonuc_2 PF01261.24 PSC69879.1 - 0.2 11.0 4.3 2.5 7.5 0.3 3.0 2 1 1 3 3 3 0 Xylose isomerase-like TIM barrel Pkinase PF00069.25 PSC69880.1 - 3.6e-64 216.7 0.0 3.1e-35 121.8 0.0 4.3 2 2 1 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 PSC69880.1 - 4.6e-50 170.3 0.0 6.2e-29 101.1 0.0 3.8 2 2 1 3 3 3 3 Protein tyrosine kinase Tub PF01167.18 PSC69880.1 - 9.2e-37 127.1 0.0 2.6e-36 125.6 0.0 1.8 1 1 0 1 1 1 1 Tub family LRR_8 PF13855.6 PSC69880.1 - 4.1e-17 61.7 1.1 6.9e-06 25.7 0.0 6.4 5 2 1 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 PSC69880.1 - 1.3e-16 60.4 8.6 0.0029 18.0 0.0 7.8 6 2 3 9 9 9 6 Leucine Rich repeats (2 copies) Pro_CA PF00484.19 PSC69880.1 - 1.9e-11 44.5 0.1 4e-11 43.5 0.1 1.6 1 0 0 1 1 1 1 Carbonic anhydrase DUF4448 PF14610.6 PSC69880.1 - 0.005 16.7 0.0 0.38 10.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) LRR_1 PF00560.33 PSC69880.1 - 0.013 16.0 1.8 2e+02 3.2 0.0 6.6 5 1 0 5 5 5 0 Leucine Rich Repeat LRRNT_2 PF08263.12 PSC69880.1 - 0.043 14.1 2.2 9.5 6.6 0.6 3.3 2 0 0 2 2 2 0 Leucine rich repeat N-terminal domain Pkinase_fungal PF17667.1 PSC69880.1 - 0.061 12.1 0.4 0.14 10.9 0.1 1.6 2 0 0 2 2 2 0 Fungal protein kinase RIO1 PF01163.22 PSC69880.1 - 0.065 12.8 0.0 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 RIO1 family TFIIA PF03153.13 PSC69881.1 - 0.065 13.2 3.1 0.13 12.2 3.1 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FUSC PF04632.12 PSC69881.1 - 9.7 4.6 10.3 20 3.6 10.3 1.4 1 0 0 1 1 1 0 Fusaric acid resistance protein family Chromo PF00385.24 PSC69882.1 - 8.6e-05 22.4 0.1 0.00035 20.4 0.1 2.0 2 0 0 2 2 2 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 PSC69882.1 - 0.14 12.4 0.1 0.28 11.4 0.1 1.6 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 YchF-GTPase_C PF06071.13 PSC69883.1 - 2.1e-37 127.1 0.9 2.1e-37 127.1 0.9 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF933) RVT_1 PF00078.27 PSC69883.1 - 6.4e-22 78.2 0.0 1.3e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) MMR_HSR1 PF01926.23 PSC69883.1 - 1.7e-20 73.2 0.0 3.9e-20 72.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PSC69883.1 - 1.9e-06 27.5 0.0 3.1e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B ABC_tran PF00005.27 PSC69883.1 - 0.021 15.4 0.0 0.17 12.4 0.0 2.1 2 0 0 2 2 2 0 ABC transporter SLBP_RNA_bind PF15247.6 PSC69883.1 - 0.22 11.6 1.4 3.7 7.7 0.2 2.4 2 0 0 2 2 2 0 Histone RNA hairpin-binding protein RNA-binding domain DUF2040 PF09745.9 PSC69884.1 - 3.5e-32 111.0 16.5 3.5e-32 111.0 16.5 2.1 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) GDI PF00996.18 PSC69885.1 - 4e-219 727.5 0.0 5.2e-219 727.1 0.0 1.1 1 0 0 1 1 1 1 GDP dissociation inhibitor Nucleotid_trans PF03407.16 PSC69885.1 - 2.3e-06 27.7 3.1 8.9e-06 25.8 3.1 1.9 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase SH3_14 PF18343.1 PSC69885.1 - 0.078 13.1 0.0 0.67 10.1 0.0 2.2 2 0 0 2 2 2 0 Dda helicase SH3 domain UPF0060 PF02694.15 PSC69886.1 - 1.3e-30 105.7 11.5 1.5e-30 105.5 11.5 1.1 1 0 0 1 1 1 1 Uncharacterised BCR, YnfA/UPF0060 family zf-CCCH PF00642.24 PSC69887.1 - 2.1e-26 91.2 42.3 2.3e-07 30.5 0.7 7.5 7 0 0 7 7 7 7 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PSC69887.1 - 7.2e-06 25.9 41.1 0.012 15.7 2.4 7.8 7 1 0 7 7 7 4 Zinc finger domain Torus PF16131.5 PSC69887.1 - 0.00013 22.6 25.1 0.3 11.8 2.3 5.4 3 1 2 5 5 5 4 Torus domain zf-CCCH_4 PF18044.1 PSC69887.1 - 0.00019 21.1 25.1 0.012 15.3 0.2 6.0 7 0 0 7 7 7 3 CCCH-type zinc finger zf-CCCH_2 PF14608.6 PSC69887.1 - 2.8 8.6 32.2 1.1 9.9 0.2 6.6 7 0 0 7 7 7 0 RNA-binding, Nab2-type zinc finger WASH-7_C PF14746.6 PSC69887.1 - 4.3 7.0 4.0 8.3 6.1 4.0 1.4 1 0 0 1 1 1 0 WASH complex subunit 7, C-terminal DEAD PF00270.29 PSC69888.1 - 5.5e-12 45.8 0.0 9.4e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DNA_pol_A PF00476.20 PSC69888.1 - 8.9e-11 41.5 0.0 1e-06 28.1 0.0 2.2 2 0 0 2 2 2 2 DNA polymerase family A EAF PF09816.9 PSC69888.1 - 1.5e-10 41.3 0.0 2.8e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor Helicase_C PF00271.31 PSC69888.1 - 1.1e-09 38.6 0.0 1.7e-08 34.8 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain F-box-like PF12937.7 PSC69888.1 - 0.00068 19.5 0.1 0.0034 17.2 0.1 2.2 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 PSC69888.1 - 0.0047 16.7 0.0 0.026 14.3 0.0 2.3 2 0 0 2 2 2 1 Leucine rich repeat TetR_C_29 PF17938.1 PSC69888.1 - 0.026 14.6 0.0 0.064 13.3 0.0 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain LRR_4 PF12799.7 PSC69888.1 - 0.047 14.1 0.0 3.5 8.2 0.0 3.3 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Nop14 PF04147.12 PSC69888.1 - 4.4 5.4 7.4 6.5 4.8 7.4 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_B_thumb PF14791.6 PSC69890.1 - 3.4e-13 49.6 0.0 1.2e-12 47.8 0.0 2.0 1 1 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 PSC69890.1 - 4.2e-13 48.9 0.1 1e-12 47.7 0.1 1.7 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 PSC69890.1 - 7e-06 26.3 0.0 8.3e-05 22.9 0.0 2.5 2 1 0 2 2 2 1 Helix-hairpin-helix domain Pex14_N PF04695.13 PSC69890.1 - 0.016 15.9 10.1 0.016 15.9 10.1 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region eIF-3_zeta PF05091.12 PSC69890.1 - 0.036 13.0 3.0 0.05 12.6 3.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CPSF100_C PF13299.6 PSC69890.1 - 0.13 12.5 1.4 0.25 11.5 1.4 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TFIIA PF03153.13 PSC69890.1 - 0.14 12.2 21.9 0.22 11.5 21.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 PSC69890.1 - 0.62 10.5 10.3 0.89 10.0 7.6 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF737 PF05300.11 PSC69891.1 - 0.23 11.8 11.0 0.3 11.4 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Jnk-SapK_ap_N PF09744.9 PSC69891.1 - 0.64 10.2 7.6 0.98 9.6 7.6 1.2 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Atg14 PF10186.9 PSC69891.1 - 0.98 8.4 3.9 1.3 8.1 3.9 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Casc1_N PF15927.5 PSC69891.1 - 5.7 6.6 17.8 9.7 5.8 17.8 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Herpes_UL25 PF01499.16 PSC69891.1 - 7.6 4.9 9.9 10 4.5 9.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family ABC1 PF03109.16 PSC69892.1 - 1.1e-35 122.4 0.0 1.8e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 PSC69892.1 - 0.00023 20.6 0.0 0.055 12.8 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 PSC69892.1 - 0.0012 18.9 0.7 0.0012 18.9 0.7 3.4 2 2 0 2 2 2 1 Phosphotransferase enzyme family WaaY PF06176.11 PSC69892.1 - 0.19 11.3 0.0 0.29 10.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) TetR_C_33 PF13305.6 PSC69892.1 - 0.33 11.7 3.9 19 6.1 0.1 3.0 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Lipase_GDSL_2 PF13472.6 PSC69893.1 - 1.7e-24 87.2 0.9 3.2e-11 44.0 0.1 2.7 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Mpv17_PMP22 PF04117.12 PSC69893.1 - 1.8e-20 72.9 1.1 4.1e-20 71.8 1.1 1.7 1 0 0 1 1 1 1 Mpv17 / PMP22 family CE2_N PF17996.1 PSC69893.1 - 3.1e-14 52.9 0.0 2.9e-07 30.5 0.0 2.5 2 0 0 2 2 2 2 Carbohydrate esterase 2 N-terminal Lipase_GDSL PF00657.22 PSC69893.1 - 2.1e-05 24.6 0.0 0.0089 16.0 0.0 2.4 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase Big_7 PF17957.1 PSC69893.1 - 0.029 15.1 0.1 0.15 12.9 0.1 2.2 2 0 0 2 2 2 0 Bacterial Ig domain Amidinotransf PF02274.17 PSC69894.1 - 8.1e-09 35.0 0.0 8.9e-08 31.6 0.0 2.0 2 0 0 2 2 2 2 Amidinotransferase CBF PF03914.17 PSC69895.1 - 4.6e-33 114.6 0.2 1.9e-32 112.7 0.0 2.1 2 1 1 3 3 3 1 CBF/Mak21 family DUF3522 PF12036.8 PSC69896.1 - 5.8e-07 30.0 1.0 7.9e-07 29.5 1.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Kazal_2 PF07648.15 PSC69897.1 - 1.2e-11 44.5 89.4 0.001 19.2 2.5 11.6 11 0 0 11 11 11 8 Kazal-type serine protease inhibitor domain LRR_4 PF12799.7 PSC69897.1 - 5e-08 33.1 0.0 0.096 13.2 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC69897.1 - 2.2e-06 27.4 6.7 0.054 13.3 0.0 4.6 5 0 0 5 5 5 3 Leucine rich repeat Kazal_1 PF00050.21 PSC69897.1 - 0.00048 20.1 76.6 0.034 14.2 1.2 10.8 10 1 0 11 11 11 7 Kazal-type serine protease inhibitor domain LRR_9 PF14580.6 PSC69897.1 - 0.049 13.1 0.0 0.86 9.1 0.0 2.3 2 0 0 2 2 2 0 Leucine-rich repeat Sulfate_transp PF00916.20 PSC69898.1 - 6.4e-99 331.3 11.2 8.7e-99 330.8 11.2 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 PSC69898.1 - 4.6e-24 84.3 0.0 7.2e-24 83.7 0.0 1.3 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 PSC69898.1 - 8.9e-05 22.8 0.1 0.00028 21.1 0.1 1.8 1 0 0 1 1 1 1 STAS domain DNA_pol_B_thumb PF14791.6 PSC69899.1 - 9.5e-19 67.3 0.0 1.9e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 PSC69899.1 - 7e-06 25.8 0.0 1.5e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda HHH_8 PF14716.6 PSC69899.1 - 2.4e-05 24.6 0.0 0.00082 19.7 0.0 2.9 3 0 0 3 3 3 1 Helix-hairpin-helix domain HHH_5 PF14520.6 PSC69899.1 - 0.17 12.5 0.0 0.45 11.2 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix domain GATA PF00320.27 PSC69900.1 - 1.2e-18 66.4 19.5 1.2e-10 40.8 4.8 5.1 6 1 0 6 6 6 2 GATA zinc finger GATA PF00320.27 PSC69901.1 - 1.2e-18 66.4 19.5 1.2e-10 40.8 4.8 5.1 6 1 0 6 6 6 2 GATA zinc finger DNA_methylase PF00145.17 PSC69902.1 - 1.9e-27 96.5 2.3 3.2e-17 62.9 0.0 2.8 3 0 0 3 3 3 2 C-5 cytosine-specific DNA methylase BTB PF00651.31 PSC69902.1 - 1.6e-23 83.1 0.1 4.7e-23 81.5 0.0 1.8 1 1 1 2 2 2 1 BTB/POZ domain BAH PF01426.18 PSC69902.1 - 0.019 14.8 0.1 0.054 13.3 0.0 1.8 2 0 0 2 2 2 0 BAH domain DNA_methylase PF00145.17 PSC69903.1 - 1.9e-27 96.5 2.3 3.2e-17 62.9 0.0 2.8 3 0 0 3 3 3 2 C-5 cytosine-specific DNA methylase BTB PF00651.31 PSC69903.1 - 1.6e-23 83.0 0.1 4.7e-23 81.5 0.0 1.8 1 1 1 2 2 2 1 BTB/POZ domain BAH PF01426.18 PSC69903.1 - 0.019 14.8 0.1 0.054 13.3 0.0 1.8 2 0 0 2 2 2 0 BAH domain SNF2_N PF00176.23 PSC69904.1 - 4.2e-53 180.3 0.0 8e-53 179.4 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC69904.1 - 5.2e-19 68.6 0.0 9.5e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 PSC69904.1 - 1.9e-18 66.1 0.0 8.5e-11 41.6 0.0 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 PSC69904.1 - 2e-05 24.7 0.0 5.1e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PSC69904.1 - 0.022 14.5 0.0 0.057 13.2 0.0 1.7 1 1 0 1 1 1 0 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 PSC69904.1 - 0.063 12.9 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase SNF2_N PF00176.23 PSC69905.1 - 1e-53 182.3 0.0 2e-53 181.4 0.0 1.4 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC69905.1 - 5.2e-19 68.6 0.0 9.5e-19 67.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 PSC69905.1 - 1.8e-18 66.1 0.0 8.4e-11 41.6 0.0 2.7 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ResIII PF04851.15 PSC69905.1 - 3.5e-05 23.9 0.0 0.00011 22.3 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PSC69905.1 - 0.00089 19.1 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 PSC69905.1 - 0.065 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 SWI2/SNF2 ATPase GATA PF00320.27 PSC69906.1 - 4.3e-19 67.8 19.5 8.1e-11 41.3 4.8 5.0 5 1 0 5 5 5 2 GATA zinc finger DUF1230 PF06799.11 PSC69909.1 - 6e-54 182.1 0.0 1e-53 181.3 0.0 1.4 1 0 0 1 1 1 1 Conserved in the green lineage and diatoms 27 CN_hydrolase PF00795.22 PSC69909.1 - 4.1e-34 118.1 0.0 6.1e-34 117.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 PSC69909.1 - 2.1e-24 86.0 0.0 7.2e-24 84.2 0.0 1.7 1 1 0 1 1 1 1 NAD synthase Tim17 PF02466.19 PSC69910.1 - 5e-15 55.8 5.9 1e-14 54.8 5.9 1.5 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4642 PF15484.6 PSC69910.1 - 0.11 12.7 6.0 0.25 11.6 6.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) Collagen_mid PF15984.5 PSC69910.1 - 0.12 12.1 0.9 0.21 11.3 0.9 1.4 1 0 0 1 1 1 0 Bacterial collagen, middle region RPA43_OB PF17875.1 PSC69910.1 - 0.23 12.1 2.8 0.66 10.6 2.8 1.7 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I CPSF100_C PF13299.6 PSC69910.1 - 0.34 11.1 4.2 0.76 9.9 1.7 2.3 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal DNA_pol_phi PF04931.13 PSC69910.1 - 7.4 4.5 10.0 11 3.9 10.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Tim17 PF02466.19 PSC69911.1 - 5e-15 55.8 5.9 1e-14 54.9 5.9 1.5 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF4642 PF15484.6 PSC69911.1 - 0.11 12.7 6.0 0.25 11.6 6.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) Collagen_mid PF15984.5 PSC69911.1 - 0.12 12.1 0.9 0.21 11.3 0.9 1.4 1 0 0 1 1 1 0 Bacterial collagen, middle region RPA43_OB PF17875.1 PSC69911.1 - 0.23 12.1 2.8 0.65 10.6 2.8 1.7 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I CPSF100_C PF13299.6 PSC69911.1 - 0.34 11.1 4.2 0.75 10.0 1.7 2.3 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal DNA_pol_phi PF04931.13 PSC69911.1 - 7.3 4.6 10.0 11 3.9 10.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi Gly-zipper_YMGG PF13441.6 PSC69911.1 - 9.2 6.1 31.5 0.91 9.3 4.9 3.5 3 0 0 3 3 3 0 YMGG-like Gly-zipper DUF2275 PF10039.9 PSC69912.1 - 0.0019 18.3 2.6 0.12 12.4 0.1 2.2 1 1 0 2 2 2 2 Predicted integral membrane protein (DUF2275) CENP-O PF09496.10 PSC69913.1 - 0.25 11.3 2.4 0.34 10.9 2.4 1.1 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component ABC_tran PF00005.27 PSC69915.1 - 3e-22 79.6 0.0 4.6e-22 79.0 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PSC69915.1 - 5e-16 58.8 4.0 7.2e-16 58.2 4.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PSC69915.1 - 2.9e-09 37.2 0.0 7.5e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Tweety PF04906.13 PSC69915.1 - 0.088 11.5 0.1 0.16 10.6 0.1 1.3 1 0 0 1 1 1 0 Tweety Aldose_epim PF01263.20 PSC69916.1 - 5.9e-14 52.1 0.0 1.7e-12 47.3 0.0 2.6 2 1 0 2 2 2 2 Aldose 1-epimerase CwfJ_C_1 PF04677.15 PSC69918.1 - 1.5e-37 128.1 0.1 2.3e-37 127.6 0.1 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 MFS_1 PF07690.16 PSC69918.1 - 4.2e-21 75.2 26.9 4.2e-21 75.2 26.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily CwfJ_C_2 PF04676.14 PSC69918.1 - 5.4e-21 75.3 0.0 5.4e-21 75.3 0.0 2.1 2 0 0 2 2 2 1 Protein similar to CwfJ C-terminus 2 MFS_1_like PF12832.7 PSC69918.1 - 3.3 6.5 8.7 5.5 5.7 8.7 1.3 1 0 0 1 1 1 0 MFS_1 like family His_Phos_1 PF00300.22 PSC69919.1 - 6.6e-27 94.5 0.0 1.3e-26 93.5 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) eIF3_subunit PF08597.10 PSC69920.1 - 0.12 12.3 7.3 0.23 11.3 7.3 1.4 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit zf-CCCH PF00642.24 PSC69922.1 - 0.00023 21.0 0.1 0.00023 21.0 0.1 3.9 4 1 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PSC69922.1 - 0.0024 17.8 0.4 0.0024 17.8 0.4 3.7 5 0 0 5 5 5 1 Zinc finger domain HTH_Crp_2 PF13545.6 PSC69922.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain zf-CCCH_2 PF14608.6 PSC69922.1 - 1.1 9.8 14.9 1.3 9.6 0.2 3.7 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 PSC69922.1 - 6.3 6.7 8.5 0.51 10.2 0.2 3.1 3 0 0 3 3 3 0 CCCH-type zinc finger DUF1631 PF07793.11 PSC69922.1 - 7.1 4.9 6.9 15 3.9 6.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) WD40 PF00400.32 PSC69923.1 - 0.00021 22.0 3.4 0.0097 16.7 0.2 4.3 4 0 0 4 4 4 1 WD domain, G-beta repeat GATA PF00320.27 PSC69924.1 - 2.1e-07 30.4 2.1 3.1e-07 29.9 2.1 1.3 1 0 0 1 1 1 1 GATA zinc finger DZR PF12773.7 PSC69924.1 - 0.053 13.6 0.2 0.51 10.4 0.4 2.0 1 1 1 2 2 2 0 Double zinc ribbon Ran-binding PF05508.11 PSC69926.1 - 4.5e-22 78.4 0.0 1e-19 70.7 0.0 2.1 1 1 0 1 1 1 1 RanGTP-binding protein DNA_pol_A PF00476.20 PSC69927.1 - 3.9e-111 371.7 0.0 5.3e-111 371.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family A DEAD PF00270.29 PSC69927.1 - 8.5e-16 58.2 0.0 4.5e-15 55.8 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC69927.1 - 2.9e-08 34.0 0.0 2.1e-07 31.3 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 PSC69927.1 - 0.036 14.7 0.0 0.2 12.3 0.0 2.4 1 0 0 1 1 1 0 Helix-hairpin-helix domain Methyltransf_16 PF10294.9 PSC69928.1 - 8.3e-19 68.0 0.0 2.8e-15 56.5 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase VDE PF07137.11 PSC69929.1 - 6.3e-81 271.4 0.0 9.4e-81 270.8 0.0 1.2 1 0 0 1 1 1 1 VDE lipocalin domain Lipase_GDSL_2 PF13472.6 PSC69929.1 - 2.2e-11 44.5 0.7 1.2e-10 42.0 0.3 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family CE2_N PF17996.1 PSC69929.1 - 1e-09 38.3 0.0 2.2e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL PF00657.22 PSC69929.1 - 1.2e-06 28.6 0.6 0.00048 20.2 1.1 2.5 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase DUF1640 PF07798.11 PSC69929.1 - 0.14 12.2 0.6 0.24 11.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Peptidase_M24 PF00557.24 PSC69930.1 - 1.1e-45 156.0 0.1 2.3e-45 154.9 0.0 1.6 2 0 0 2 2 2 1 Metallopeptidase family M24 Creatinase_N_2 PF16189.5 PSC69930.1 - 2.8e-44 151.1 0.0 5.7e-43 146.8 0.0 2.5 2 1 0 2 2 2 1 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 PSC69930.1 - 1.5e-24 85.8 0.1 4.2e-24 84.4 0.1 1.8 1 0 0 1 1 1 1 C-terminal region of peptidase_M24 Creatinase_N PF01321.18 PSC69930.1 - 7.5e-20 71.9 0.0 6.3e-15 56.0 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain rve PF00665.26 PSC69931.1 - 6.3e-19 68.3 0.0 1.3e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC69931.1 - 0.0058 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Exostosin PF03016.15 PSC69932.1 - 4.1e-23 82.0 0.4 5.5e-23 81.6 0.4 1.1 1 0 0 1 1 1 1 Exostosin family EGF_2 PF07974.13 PSC69932.1 - 7.3e-06 26.3 29.2 0.00016 22.0 4.3 4.4 5 0 0 5 5 5 3 EGF-like domain EGF_Tenascin PF18720.1 PSC69932.1 - 2.5 8.2 25.6 0.76 9.9 2.6 3.6 3 0 0 3 3 3 0 Tenascin EGF domain Laminin_EGF PF00053.24 PSC69932.1 - 5.3 7.3 29.1 1.4 9.1 6.6 3.8 3 0 0 3 3 3 0 Laminin EGF domain CutC PF03932.14 PSC69933.1 - 4.9e-73 244.9 1.4 5.9e-73 244.7 1.4 1.1 1 0 0 1 1 1 1 CutC family RtcB PF01139.17 PSC69934.1 - 2.7e-91 306.8 1.7 1.3e-65 222.2 0.1 2.1 1 1 1 2 2 2 2 tRNA-splicing ligase RtcB Pro_CA PF00484.19 PSC69934.1 - 9.2e-18 65.0 0.2 8e-16 58.7 0.1 2.4 2 0 0 2 2 2 2 Carbonic anhydrase SURF1 PF02104.15 PSC69935.1 - 1.4e-37 129.6 0.1 1.9e-37 129.2 0.1 1.1 1 0 0 1 1 1 1 SURF1 family Rhodanese PF00581.20 PSC69936.1 - 4.2e-07 30.5 0.0 6.5e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 Rhodanese-like domain DUF3685 PF12452.8 PSC69937.1 - 8.5e-18 64.8 0.1 1.7e-17 63.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3685) DUF2722 PF10846.8 PSC69937.1 - 0.31 9.9 5.1 0.81 8.6 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) KCNQ2_u3 PF16642.5 PSC69937.1 - 1.4 10.0 9.9 3.8 8.5 0.7 2.6 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 PTS_IIA PF02255.16 PSC69938.1 - 1.1 9.4 4.8 11 6.2 0.3 3.0 3 1 1 4 4 4 0 PTS system, Lactose/Cellobiose specific IIA subunit MFS_1_like PF12832.7 PSC69940.1 - 2.1e-76 257.3 0.0 3.5e-76 256.5 0.0 1.3 1 1 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 PSC69940.1 - 1.1e-19 70.6 44.0 6.9e-16 58.1 24.8 2.3 1 1 2 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 PSC69940.1 - 7.6e-10 38.3 12.3 1.4e-08 34.1 0.7 2.1 2 0 0 2 2 2 2 Nucleoside H+ symporter LacY_symp PF01306.19 PSC69940.1 - 2e-06 26.9 6.5 0.00039 19.3 3.2 3.0 2 1 0 2 2 2 2 LacY proton/sugar symporter Hist_deacetyl PF00850.19 PSC69941.1 - 2.7e-78 263.6 0.4 5.2e-78 262.6 0.0 1.7 2 0 0 2 2 2 1 Histone deacetylase domain DUF4033 PF13225.6 PSC69941.1 - 1.2e-34 118.1 0.1 2.3e-34 117.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) rve PF00665.26 PSC69941.1 - 3e-18 66.1 0.0 6.1e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC69941.1 - 0.0036 17.0 0.0 0.0082 15.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain TPT PF03151.16 PSC69942.1 - 3.8e-19 69.1 16.2 4.6e-19 68.9 16.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family TPT PF03151.16 PSC69943.1 - 4.4e-19 68.9 16.2 5.3e-19 68.7 16.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Hemerythrin PF01814.23 PSC69944.1 - 0.1 13.2 2.1 0.15 12.7 2.1 1.3 1 0 0 1 1 1 0 Hemerythrin HHE cation binding domain Acetyltransf_7 PF13508.7 PSC69945.1 - 8.7e-08 32.5 0.0 1.3e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PSC69945.1 - 1.4e-07 31.7 0.0 1.9e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PSC69945.1 - 0.0013 18.7 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC69945.1 - 0.019 15.0 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_CG PF14542.6 PSC69945.1 - 0.12 12.5 0.8 0.66 10.1 0.0 2.0 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase UQ_con PF00179.26 PSC69946.1 - 8.8e-27 93.5 0.0 1.1e-26 93.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PQQ_3 PF13570.6 PSC69947.1 - 2.8e-06 27.6 1.2 0.03 14.8 0.0 4.3 4 0 0 4 4 4 2 PQQ-like domain WD40 PF00400.32 PSC69947.1 - 0.022 15.6 17.1 0.076 13.9 0.0 6.3 7 0 0 7 7 7 0 WD domain, G-beta repeat SET PF00856.28 PSC69948.1 - 1.1e-07 32.4 0.0 2.7e-05 24.6 0.0 3.2 3 1 0 3 3 3 1 SET domain Rubis-subs-bind PF09273.11 PSC69948.1 - 8.9e-05 23.2 5.9 0.00031 21.4 5.9 1.9 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding Hist_deacetyl PF00850.19 PSC69949.1 - 2.9e-79 266.8 0.0 4.2e-79 266.2 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain GATA PF00320.27 PSC69949.1 - 1.2e-20 72.8 19.5 2.3e-10 39.9 4.8 2.6 2 0 0 2 2 2 2 GATA zinc finger TF_Zn_Ribbon PF08271.12 PSC69949.1 - 0.04 13.4 9.8 0.069 12.7 3.5 2.6 2 0 0 2 2 2 0 TFIIB zinc-binding zf-C4pol PF14260.6 PSC69949.1 - 1.4 9.4 8.1 1.6 9.3 6.6 1.9 2 1 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DZR PF12773.7 PSC69949.1 - 2.5 8.2 12.3 26 4.9 12.6 2.5 1 1 1 2 2 2 0 Double zinc ribbon NMD3 PF04981.13 PSC69949.1 - 3.1 7.2 8.5 6 6.3 1.5 2.1 1 1 1 2 2 2 0 NMD3 family PhoD PF09423.10 PSC69950.1 - 0.00052 19.1 0.0 0.026 13.5 0.0 2.3 2 0 0 2 2 2 2 PhoD-like phosphatase NCOA_u2 PF16665.5 PSC69950.1 - 0.05 13.9 0.6 0.1 12.9 0.6 1.4 1 0 0 1 1 1 0 Unstructured region on nuclear receptor coactivator protein TMEM154 PF15102.6 PSC69950.1 - 0.096 12.6 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family Semialdhyde_dhC PF02774.18 PSC69951.1 - 4e-44 150.9 0.0 6.1e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain Semialdhyde_dh PF01118.24 PSC69951.1 - 2.6e-31 108.5 0.0 6.3e-31 107.3 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain START PF01852.19 PSC69951.1 - 0.00016 21.2 0.0 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 START domain Gp_dh_C PF02800.20 PSC69951.1 - 0.073 12.7 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain DUF647 PF04884.14 PSC69952.1 - 7.8e-64 215.6 1.8 1.8e-63 214.4 1.8 1.6 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis zf-MYND PF01753.18 PSC69952.1 - 0.0013 18.8 9.0 0.0013 18.8 9.0 2.6 2 0 0 2 2 2 1 MYND finger zf-CCCH_4 PF18044.1 PSC69952.1 - 1.8 8.5 13.7 2.6 8.0 2.6 3.3 2 2 0 2 2 2 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 PSC69952.1 - 9.4 6.9 11.8 17 6.1 3.4 2.5 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger ECH_1 PF00378.20 PSC69953.1 - 3.2e-41 141.3 0.2 4.9e-41 140.7 0.2 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PSC69953.1 - 6.7e-28 98.1 0.4 1.5e-27 97.0 0.4 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Phage_TAC_4 PF08748.11 PSC69953.1 - 0.009 16.3 0.1 0.025 14.9 0.1 1.7 2 0 0 2 2 2 1 Phage tail assembly chaperone TusA PF01206.17 PSC69953.1 - 0.19 11.6 0.0 3.4 7.6 0.0 2.3 2 0 0 2 2 2 0 Sulfurtransferase TusA Peptidase_S49 PF01343.18 PSC69953.1 - 0.75 9.7 3.0 2.9 7.8 0.1 2.7 2 1 1 3 3 3 0 Peptidase family S49 Na_H_Exchanger PF00999.21 PSC69954.1 - 5.6e-27 94.5 40.2 8.5e-27 93.9 40.2 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family cNMP_binding PF00027.29 PSC69954.1 - 0.063 13.4 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain DAP3 PF10236.9 PSC69955.1 - 1.4e-18 67.1 0.0 1.3e-16 60.7 0.0 2.9 2 1 0 2 2 2 1 Mitochondrial ribosomal death-associated protein 3 Glyco_hydro_88 PF07470.13 PSC69955.1 - 0.088 11.9 0.2 0.14 11.2 0.2 1.2 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 AAA_16 PF13191.6 PSC69955.1 - 0.3 11.5 3.4 0.32 11.4 0.1 2.2 2 0 0 2 2 2 0 AAA ATPase domain Wzy_C PF04932.15 PSC69956.1 - 0.043 13.5 0.0 0.056 13.1 0.0 1.2 1 0 0 1 1 1 0 O-Antigen ligase IlvC PF01450.19 PSC69958.1 - 2.5e-51 173.8 0.6 2.1e-31 109.1 0.0 3.2 2 1 1 3 3 3 3 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.12 PSC69958.1 - 1.3e-34 119.2 0.2 2.2e-34 118.4 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain IlvC PF01450.19 PSC69959.1 - 1.8e-43 148.3 0.5 9.6e-35 120.0 0.1 2.2 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.12 PSC69959.1 - 1.1e-34 119.3 0.2 2e-34 118.5 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Bac_rhamnosid PF05592.11 PSC69959.1 - 0.15 12.1 0.0 0.51 10.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain IlvC PF01450.19 PSC69960.1 - 2e-42 144.9 0.4 1.1e-33 116.6 0.1 2.2 2 0 0 2 2 2 2 Acetohydroxy acid isomeroreductase, catalytic domain IlvN PF07991.12 PSC69960.1 - 1.2e-34 119.3 0.2 2e-34 118.5 0.2 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Bac_rhamnosid PF05592.11 PSC69960.1 - 0.15 12.0 0.0 0.51 10.4 0.0 1.8 2 0 0 2 2 2 0 Bacterial alpha-L-rhamnosidase concanavalin-like domain LRR_4 PF12799.7 PSC69961.1 - 7.7e-19 67.5 14.2 0.00079 19.8 0.8 7.9 4 3 7 11 11 11 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC69961.1 - 1.6e-18 66.2 13.7 1.2e-08 34.6 0.2 5.5 5 2 1 6 6 6 4 Leucine rich repeat LRR_1 PF00560.33 PSC69961.1 - 1.7e-06 27.7 17.3 5.7 7.9 0.0 8.8 9 0 0 9 9 9 3 Leucine Rich Repeat F-box-like PF12937.7 PSC69961.1 - 0.0023 17.8 1.1 0.0048 16.8 0.1 2.1 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.6 PSC69961.1 - 0.05 13.7 19.3 6.9 7.0 0.1 6.8 8 0 0 8 8 8 0 Leucine Rich repeat Ribosomal_S6 PF01250.17 PSC69962.1 - 3.9e-16 59.1 0.0 6.9e-16 58.3 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S6 Beta-lactamase PF00144.24 PSC69963.1 - 0.014 14.7 0.6 0.02 14.1 0.6 1.3 1 0 0 1 1 1 0 Beta-lactamase Citrate_synt PF00285.21 PSC69965.1 - 1.2e-23 83.8 0.0 7.3e-21 74.6 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 PSC69965.1 - 1.3e-13 51.1 0.1 2.2e-13 50.3 0.1 1.4 1 0 0 1 1 1 1 CoA-ligase Succ_CoA_lig PF13607.6 PSC69965.1 - 3.1e-06 27.0 0.2 1.7e-05 24.6 0.1 2.1 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain UDG PF03167.19 PSC69966.1 - 2.5e-07 30.8 0.0 6.2e-07 29.5 0.0 1.6 2 0 0 2 2 2 1 Uracil DNA glycosylase superfamily tRNA_edit PF04073.15 PSC69967.1 - 1.5e-24 86.4 1.0 5.6e-24 84.6 0.1 2.2 2 0 0 2 2 2 1 Aminoacyl-tRNA editing domain ZapB PF06005.12 PSC69967.1 - 0.14 12.6 5.9 0.31 11.5 5.9 1.6 1 0 0 1 1 1 0 Cell division protein ZapB DUF3416 PF11896.8 PSC69967.1 - 4.4 7.6 6.4 1 9.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3416) rve PF00665.26 PSC69968.1 - 2.9e-18 66.2 0.0 5.8e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC69968.1 - 0.0073 16.1 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Nramp PF01566.18 PSC69969.1 - 7.5e-109 364.0 15.4 7.5e-109 364.0 15.4 1.5 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein ResIII PF04851.15 PSC69969.1 - 2.2e-25 89.6 0.0 3.8e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PSC69969.1 - 3.5e-14 53.1 0.0 2.6e-13 50.3 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 PSC69969.1 - 8.3e-10 38.7 0.0 1.3e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DEAD PF00270.29 PSC69969.1 - 9.8e-09 35.2 0.1 1.6e-08 34.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 PSC69969.1 - 0.0044 16.3 0.0 0.007 15.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Flavi_DEAD PF07652.14 PSC69969.1 - 0.013 15.5 0.1 0.032 14.2 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_11 PF13086.6 PSC69969.1 - 0.021 14.6 0.4 0.61 9.8 0.1 2.2 1 1 1 2 2 2 0 AAA domain TniB PF05621.11 PSC69969.1 - 0.14 11.6 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 PSC69969.1 - 0.19 12.0 0.1 0.66 10.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PSC69969.1 - 0.53 10.7 3.3 0.68 10.3 0.1 2.7 2 0 0 2 2 2 0 AAA ATPase domain Hemerythrin PF01814.23 PSC69970.1 - 3.6e-07 30.9 0.1 7.9e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain CtnDOT_TraJ PF07863.11 PSC69970.1 - 9.2 7.0 9.3 3.8 8.2 0.0 3.3 2 1 0 2 2 2 0 Homologues of TraJ from Bacteroides conjugative transposon DAGK_cat PF00781.24 PSC69971.1 - 1.1e-26 92.9 0.1 2.2e-26 91.9 0.1 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 PSC69971.1 - 0.13 11.4 0.0 0.25 10.5 0.0 1.4 1 0 0 1 1 1 0 ATP-NAD kinase FHA PF00498.26 PSC69972.1 - 4.3e-17 62.2 0.0 6.9e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 PSC69972.1 - 0.00044 20.5 0.0 0.0017 18.6 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain BTB PF00651.31 PSC69973.1 - 2.8e-08 34.0 0.0 1.2e-07 31.9 0.0 1.9 1 1 1 2 2 2 1 BTB/POZ domain Nucleoporin_FG PF13634.6 PSC69974.1 - 0.004 18.0 21.2 0.004 18.0 21.2 11.8 4 2 7 11 11 11 4 Nucleoporin FG repeat region Lectin_N PF03954.14 PSC69974.1 - 0.41 10.4 1.2 1 9.1 1.2 1.6 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Nucleoporin_FG PF13634.6 PSC69975.1 - 0.00011 23.0 53.0 0.00064 20.5 25.2 12.5 5 2 8 13 13 13 5 Nucleoporin FG repeat region Lectin_N PF03954.14 PSC69975.1 - 0.43 10.3 1.2 1.1 9.1 1.2 1.6 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain MTP18 PF10558.9 PSC69976.1 - 1.2e-11 44.9 1.8 1.9e-09 37.7 0.1 2.8 1 1 1 2 2 2 2 Mitochondrial 18 KDa protein (MTP18) ORC2 PF04084.14 PSC69977.1 - 4.6e-82 275.6 0.0 5.2e-82 275.4 0.0 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Ras PF00071.22 PSC69978.1 - 5.5e-58 195.1 0.2 7.8e-58 194.6 0.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PSC69978.1 - 2.7e-37 127.6 0.1 5.8e-37 126.6 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PSC69978.1 - 2.8e-14 53.0 0.2 3.7e-14 52.6 0.2 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PSC69978.1 - 1.5e-05 24.5 0.1 2.1e-05 24.0 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PSC69978.1 - 4.6e-05 23.5 0.0 8.2e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 PSC69978.1 - 8.1e-05 22.2 0.1 0.00027 20.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 PSC69978.1 - 9.1e-05 22.0 0.1 0.00014 21.3 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 PSC69978.1 - 0.00059 19.8 0.0 0.1 12.5 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase FeoB_N PF02421.18 PSC69978.1 - 0.0025 17.3 0.1 0.029 13.9 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_7 PF12775.7 PSC69978.1 - 0.042 13.4 0.1 0.077 12.5 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TIR_2 PF13676.6 PSC69978.1 - 0.052 14.2 0.1 0.12 13.0 0.1 1.6 1 0 0 1 1 1 0 TIR domain TniB PF05621.11 PSC69978.1 - 0.1 12.0 0.0 0.55 9.6 0.0 2.1 2 0 0 2 2 2 0 Bacterial TniB protein DEAD_2 PF06733.15 PSC69979.1 - 2.5e-46 157.5 0.0 4.9e-46 156.6 0.0 1.5 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 PSC69979.1 - 9.9e-46 156.0 0.0 8.3e-35 120.5 0.0 2.4 2 0 0 2 2 2 2 Helicase C-terminal domain ResIII PF04851.15 PSC69979.1 - 0.015 15.3 0.0 2 8.4 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit DEAD PF00270.29 PSC69979.1 - 0.12 12.1 2.8 0.43 10.3 2.8 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase tRNA-synt_2 PF00152.20 PSC69980.1 - 3e-79 266.3 0.0 3.9e-79 266.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 PSC69980.1 - 3.8e-14 52.4 0.0 1.2e-13 50.9 0.0 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 PSC69980.1 - 1.1e-06 28.3 0.0 0.0083 15.6 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Prp19 PF08606.11 PSC69980.1 - 0.6 10.1 3.1 1.2 9.2 3.1 1.4 1 0 0 1 1 1 0 Prp19/Pso4-like DUF1995 PF09353.10 PSC69981.1 - 6.7e-09 36.1 0.0 7.3e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) PHD PF00628.29 PSC69982.1 - 0.1 12.5 27.6 0.085 12.8 1.6 3.4 3 0 0 3 3 3 0 PHD-finger C1_1 PF00130.22 PSC69982.1 - 0.32 10.9 28.6 0.32 10.9 3.4 3.4 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SUIM_assoc PF16619.5 PSC69982.1 - 2.6 8.2 7.9 0.31 11.2 2.2 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PHD PF00628.29 PSC69983.1 - 0.099 12.6 27.6 0.085 12.8 1.6 3.4 3 0 0 3 3 3 0 PHD-finger C1_1 PF00130.22 PSC69983.1 - 0.32 10.9 28.6 0.32 10.9 3.4 3.4 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) SUIM_assoc PF16619.5 PSC69983.1 - 2.6 8.2 7.9 0.3 11.2 2.2 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HECT PF00632.25 PSC69984.1 - 1.3e-92 310.6 0.0 1.7e-92 310.2 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF913 PF06025.12 PSC69984.1 - 5.2e-74 249.4 0.0 4.3e-73 246.4 0.0 2.6 2 0 0 2 2 2 1 Domain of Unknown Function (DUF913) DUF908 PF06012.12 PSC69984.1 - 1.9e-33 116.4 0.2 2.4e-20 73.3 0.0 3.0 2 0 0 2 2 2 2 Domain of Unknown Function (DUF908) UBM PF14377.6 PSC69984.1 - 5e-16 57.5 42.6 6.9e-10 38.0 3.8 5.3 5 1 1 6 6 6 3 Ubiquitin binding region UBA PF00627.31 PSC69984.1 - 7.9e-12 44.8 0.2 3.3e-11 42.8 0.2 2.2 1 0 0 1 1 1 1 UBA/TS-N domain PMSR PF01625.21 PSC69985.1 - 4.5e-57 192.5 1.1 5.8e-57 192.2 1.1 1.1 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Iso_dh PF00180.20 PSC69987.1 - 8.7e-131 436.2 0.0 1e-130 436.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Gpr1_Fun34_YaaH PF01184.19 PSC69988.1 - 8.9e-38 130.0 13.3 1.3e-37 129.5 13.3 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family Mito_carr PF00153.27 PSC69989.1 - 9e-43 144.1 8.3 1.1e-21 76.6 0.1 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein ENT PF03735.14 PSC69990.1 - 0.0019 18.2 0.1 0.0036 17.3 0.1 1.3 1 0 0 1 1 1 1 ENT domain TFIIA PF03153.13 PSC69990.1 - 3 7.7 21.1 0.22 11.5 15.4 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit HA2 PF04408.23 PSC69991.1 - 3.8e-18 65.7 1.6 6.6e-18 65.0 0.0 2.2 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 PSC69991.1 - 8.6e-13 48.6 0.0 1.9e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 PSC69991.1 - 1.7e-08 34.7 0.0 3.5e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold AAA_19 PF13245.6 PSC69991.1 - 1.2e-05 25.7 0.0 0.0001 22.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 PSC69991.1 - 4.1e-05 23.4 0.0 8.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PSC69991.1 - 4.5e-05 23.8 0.4 0.0002 21.6 0.1 2.3 2 1 0 2 2 2 1 AAA domain SRP54 PF00448.22 PSC69991.1 - 0.013 15.1 0.9 0.072 12.7 0.2 2.5 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 PSC69991.1 - 0.055 14.0 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain Caf4 PF11615.8 PSC69991.1 - 0.085 12.8 0.0 0.24 11.4 0.0 1.7 1 0 0 1 1 1 0 CCR4-associated factor 4 AAA_7 PF12775.7 PSC69991.1 - 0.11 12.1 0.0 0.21 11.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 PSC69991.1 - 0.16 12.5 0.0 0.4 11.2 0.0 1.6 1 0 0 1 1 1 0 ABC transporter AAA PF00004.29 PSC69994.1 - 1.3e-40 138.9 0.0 2e-37 128.6 0.0 3.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FKBP_C PF00254.28 PSC69994.1 - 9.2e-30 102.8 0.1 5.4e-29 100.4 0.0 2.2 2 0 0 2 2 2 1 FKBP-type peptidyl-prolyl cis-trans isomerase NPL PF17800.1 PSC69994.1 - 8.5e-16 58.4 1.3 2.6e-15 56.9 0.0 2.5 2 0 0 2 2 1 1 Nucleoplasmin-like domain AAA_lid_3 PF17862.1 PSC69994.1 - 3.5e-07 29.9 0.5 1.2e-06 28.2 0.5 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 PSC69994.1 - 4.7e-05 23.7 0.1 0.0048 17.2 0.1 2.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 PSC69994.1 - 0.00036 20.3 0.0 0.00083 19.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 PSC69994.1 - 0.00061 19.9 0.0 0.0089 16.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 PSC69994.1 - 0.0012 18.8 0.2 0.0055 16.7 0.2 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) SDA1 PF05285.12 PSC69994.1 - 0.0014 18.2 28.2 0.0014 18.2 28.2 1.8 2 0 0 2 2 1 1 SDA1 SH3_12 PF18129.1 PSC69994.1 - 0.0017 18.4 0.0 0.0052 16.9 0.0 1.8 1 0 0 1 1 1 1 Xrn1 SH3-like domain Sigma54_activat PF00158.26 PSC69994.1 - 0.0028 17.4 0.0 0.011 15.5 0.0 1.9 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_33 PF13671.6 PSC69994.1 - 0.0037 17.4 0.2 0.024 14.8 0.0 2.7 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 PSC69994.1 - 0.0052 16.5 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 PSC69994.1 - 0.0055 16.2 0.1 0.024 14.1 0.1 1.9 1 1 0 1 1 1 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 PSC69994.1 - 0.0058 16.0 0.1 0.014 14.8 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 PSC69994.1 - 0.0093 15.2 0.0 0.017 14.4 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 PSC69994.1 - 0.013 16.0 0.0 0.056 14.0 0.0 2.1 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 PSC69994.1 - 0.015 15.4 0.0 0.06 13.4 0.0 1.9 1 1 1 2 2 2 0 AAA domain AAA_16 PF13191.6 PSC69994.1 - 0.033 14.6 0.2 0.033 14.6 0.2 5.5 6 2 0 6 6 5 0 AAA ATPase domain DUF815 PF05673.13 PSC69994.1 - 0.077 12.1 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 PSC69994.1 - 0.13 12.6 0.0 0.34 11.3 0.0 1.8 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 PSC69994.1 - 0.15 11.8 0.0 0.37 10.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain Lipase_GDSL_2 PF13472.6 PSC69995.1 - 1.3e-24 87.6 0.1 2.3e-12 47.6 0.0 2.9 3 0 0 3 3 3 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 PSC69995.1 - 0.0049 16.9 0.0 2.5 8.0 0.0 2.9 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase Apolipoprotein PF01442.18 PSC69996.1 - 0.022 14.6 25.5 0.34 10.8 13.0 2.1 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain HTH_54 PF18607.1 PSC69996.1 - 0.74 9.9 2.0 4.4 7.4 0.3 2.6 3 0 0 3 3 3 0 ParA helix turn helix domain Apolipoprotein PF01442.18 PSC69997.1 - 0.0032 17.4 11.0 0.0038 17.1 11.0 1.1 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF2884 PF11101.8 PSC69997.1 - 0.12 11.9 1.3 0.13 11.7 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) DUF883 PF05957.13 PSC69997.1 - 0.43 11.2 18.9 1.1 9.9 8.3 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF4407 PF14362.6 PSC69997.1 - 6.6 6.0 14.1 7.7 5.8 14.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF1115 PF06544.12 PSC69998.1 - 2.5e-06 27.7 0.0 3.7e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) LCIB_C_CA PF18599.1 PSC69999.1 - 3.1e-75 252.3 0.0 6.5e-75 251.2 0.0 1.6 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Bestrophin PF01062.21 PSC69999.1 - 8.5e-49 166.5 0.9 1.5e-48 165.7 0.1 1.7 2 0 0 2 2 2 1 Bestrophin, RFP-TM, chloride channel Peptidase_S8 PF00082.22 PSC70000.1 - 2.8e-34 118.7 12.7 4e-34 118.2 12.7 1.2 1 0 0 1 1 1 1 Subtilase family RNB PF00773.19 PSC70001.1 - 2.9e-101 339.1 0.0 3.5e-101 338.8 0.0 1.1 1 0 0 1 1 1 1 RNB domain OB_Dis3 PF17849.1 PSC70001.1 - 3.2e-21 75.1 0.0 6.1e-21 74.2 0.0 1.5 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 PSC70001.1 - 5e-05 23.1 0.0 8.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Rrp44-like cold shock domain Dis3l2_C_term PF17877.1 PSC70001.1 - 0.0069 16.7 0.0 0.013 15.8 0.0 1.4 1 0 0 1 1 1 1 DIS3-like exonuclease 2 C terminal CSD2 PF17876.1 PSC70001.1 - 0.016 15.4 0.0 0.65 10.2 0.0 2.8 2 0 0 2 2 2 0 Cold shock domain CBM_20 PF00686.19 PSC70002.1 - 8.3e-10 38.4 0.0 1.5e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Starch binding domain UPF0184 PF03670.13 PSC70002.1 - 0.21 12.0 1.0 0.39 11.1 0.3 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) TcpQ PF10671.9 PSC70002.1 - 0.3 11.2 2.3 0.36 11.0 0.1 2.3 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q DASH_Spc19 PF08287.11 PSC70002.1 - 1.6 8.6 7.2 0.095 12.6 1.0 1.9 2 0 0 2 2 2 0 Spc19 Pkinase PF00069.25 PSC70004.1 - 1.1e-68 231.4 0.0 1.5e-68 231.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EF-hand_1 PF00036.32 PSC70004.1 - 6.2e-30 100.5 5.5 2.4e-07 29.8 0.0 4.6 4 0 0 4 4 4 4 EF hand Pkinase_Tyr PF07714.17 PSC70004.1 - 5.2e-25 88.2 0.0 7.4e-25 87.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_6 PF13405.6 PSC70004.1 - 3.3e-24 82.7 2.7 1.5e-06 27.7 0.1 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 PSC70004.1 - 8.1e-23 80.7 2.5 4e-11 43.2 0.3 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PSC70004.1 - 3.2e-21 73.8 7.4 2.4e-06 26.8 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 PSC70004.1 - 7.2e-14 51.4 5.2 1.8e-06 27.7 0.1 4.5 2 2 2 4 4 4 3 EF-hand domain pair Kinase-like PF14531.6 PSC70004.1 - 1.9e-07 30.7 0.4 0.00025 20.5 0.2 2.9 2 1 0 2 2 2 2 Kinase-like EF-hand_4 PF12763.7 PSC70004.1 - 3.6e-06 26.9 0.1 0.0028 17.6 0.0 2.4 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand Kdo PF06293.14 PSC70004.1 - 4.3e-06 26.2 0.1 7.3e-06 25.5 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SPARC_Ca_bdg PF10591.9 PSC70004.1 - 0.0079 16.5 0.0 5.3 7.4 0.0 2.5 1 1 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region Pkinase_fungal PF17667.1 PSC70004.1 - 0.014 14.2 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 PSC70004.1 - 0.015 14.9 0.0 0.058 13.0 0.0 1.9 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 PSC70004.1 - 0.027 14.4 3.1 1.9 8.4 0.1 3.0 3 1 1 4 4 4 0 Phosphotransferase enzyme family Pilus_CpaD PF09476.10 PSC70004.1 - 0.061 13.0 0.3 0.18 11.5 0.0 1.9 3 0 0 3 3 3 0 Pilus biogenesis CpaD protein (pilus_cpaD) Caleosin PF05042.13 PSC70004.1 - 0.14 12.0 0.1 22 4.9 0.1 2.8 2 1 0 2 2 2 0 Caleosin related protein Topoisom_I_N PF02919.15 PSC70005.1 - 2.1e-90 301.9 3.7 5.6e-90 300.5 3.7 1.8 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.20 PSC70005.1 - 7.1e-89 297.0 4.8 1.2e-88 296.3 4.8 1.4 1 0 0 1 1 1 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.6 PSC70005.1 - 1.4e-31 108.2 0.2 3.7e-31 106.9 0.2 1.8 1 0 0 1 1 1 1 C-terminal topoisomerase domain DUF4201 PF13870.6 PSC70005.1 - 1.9e-26 92.9 2.3 1.9e-26 92.9 2.3 3.9 4 0 0 4 4 4 1 Domain of unknown function (DUF4201) TPT PF03151.16 PSC70006.1 - 8e-10 38.5 10.6 1.5e-07 31.0 7.0 2.0 1 1 1 2 2 2 2 Triose-phosphate Transporter family EamA PF00892.20 PSC70006.1 - 7.4e-05 22.9 15.4 0.00027 21.1 0.2 3.1 2 1 1 3 3 3 3 EamA-like transporter family YGGT PF02325.17 PSC70007.1 - 5.1e-16 58.8 5.1 9.5e-16 58.0 5.1 1.5 1 0 0 1 1 1 1 YGGT family Nucleoside_tran PF01733.18 PSC70008.1 - 5.8e-41 140.9 10.9 5.4e-26 91.7 6.4 2.1 2 0 0 2 2 2 2 Nucleoside transporter Met_gamma_lyase PF06838.11 PSC70010.1 - 1.6e-164 547.3 0.0 1.8e-164 547.1 0.0 1.0 1 0 0 1 1 1 1 Methionine gamma-lyase Cys_Met_Meta_PP PF01053.20 PSC70010.1 - 1.1e-07 30.8 0.0 2.8e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 PSC70010.1 - 0.00027 20.2 0.0 0.00059 19.1 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class I and II PDZ_6 PF17820.1 PSC70010.1 - 0.048 13.5 0.0 0.18 11.7 0.0 2.0 1 0 0 1 1 1 0 PDZ domain ALAD PF00490.21 PSC70010.1 - 0.15 11.2 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Delta-aminolevulinic acid dehydratase Nucleotid_trans PF03407.16 PSC70011.1 - 1.8e-24 86.9 0.0 2.9e-24 86.2 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase zf-CCCH PF00642.24 PSC70011.1 - 0.012 15.5 11.3 0.028 14.3 0.3 3.5 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 PSC70011.1 - 0.04 14.4 15.2 3.6 8.2 0.3 3.7 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 PSC70011.1 - 0.056 13.5 0.5 0.056 13.5 0.5 3.6 3 0 0 3 3 3 0 Zinc finger domain Glyco_transf_34 PF05637.12 PSC70011.1 - 0.19 11.5 0.0 0.55 9.9 0.0 1.6 1 1 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family Pkinase PF00069.25 PSC70012.1 - 1.4e-29 103.3 0.0 2.2e-29 102.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC70012.1 - 2.5e-23 82.7 0.0 4e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase rve PF00665.26 PSC70012.1 - 2.8e-17 63.0 0.0 6.1e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC70012.1 - 0.088 12.6 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain LRR_8 PF13855.6 PSC70012.1 - 0.32 10.8 6.3 0.1 12.4 0.9 2.9 4 0 0 4 4 4 0 Leucine rich repeat Peptidase_S26 PF10502.9 PSC70013.1 - 1.7e-14 53.8 0.0 2.7e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Signal peptidase, peptidase S26 Peptidase_S24 PF00717.23 PSC70013.1 - 3e-09 36.7 0.1 6e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase S24-like Ferritin PF00210.24 PSC70014.1 - 3.2e-29 101.7 1.9 4.2e-29 101.3 1.9 1.1 1 0 0 1 1 1 1 Ferritin-like domain CBM_14 PF01607.24 PSC70014.1 - 0.61 10.3 2.1 0.89 9.8 1.3 1.7 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain zf-MYND PF01753.18 PSC70015.1 - 8.6e-08 32.1 21.9 8.6e-08 32.1 21.9 1.6 2 0 0 2 2 2 1 MYND finger Glyco_transf_49 PF13896.6 PSC70016.1 - 7.6e-15 55.1 0.5 9.5e-15 54.8 0.5 1.1 1 0 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_transf_49 PF13896.6 PSC70017.1 - 1e-19 71.1 3.5 1.9e-14 53.8 0.5 3.1 2 1 0 2 2 2 2 Glycosyl-transferase for dystroglycan Transglut_core2 PF13369.6 PSC70018.1 - 5.7e-16 58.4 0.0 1e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Transglutaminase-like superfamily TPR_9 PF13371.6 PSC70018.1 - 0.0043 17.2 2.7 0.0043 17.2 2.7 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 PSC70018.1 - 0.042 14.2 0.4 0.042 14.2 0.4 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat Nterm_IS4 PF13006.7 PSC70018.1 - 0.042 14.0 0.0 0.097 12.9 0.0 1.5 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal DUF1889 PF08986.10 PSC70018.1 - 0.23 11.9 1.2 5.8 7.4 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1889) LRR_6 PF13516.6 PSC70019.1 - 1.8e-52 170.9 33.8 9.4e-07 28.4 0.3 13.8 13 0 0 13 13 13 12 Leucine Rich repeat LRR_1 PF00560.33 PSC70019.1 - 4.2e-10 38.7 0.0 11 7.0 0.0 8.6 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_4 PF12799.7 PSC70019.1 - 1.9e-09 37.7 10.1 0.0059 17.0 0.6 5.9 4 2 0 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC70019.1 - 2.6e-09 36.7 14.2 0.41 10.5 1.1 6.8 5 4 0 5 5 5 4 Leucine rich repeat SpoU_sub_bind PF08032.12 PSC70019.1 - 0.23 11.8 1.0 48 4.3 0.0 4.5 4 1 2 6 6 6 0 RNA 2'-O ribose methyltransferase substrate binding Methyltransf_31 PF13847.6 PSC70020.1 - 5.4e-26 91.2 0.0 9.2e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC70020.1 - 1.3e-17 64.2 0.1 2.4e-17 63.4 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC70020.1 - 8.8e-16 58.3 0.0 1.5e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC70020.1 - 3.6e-11 42.8 0.0 1.5e-10 40.8 0.0 1.7 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 PSC70020.1 - 1.2e-10 41.5 0.0 1.7e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC70020.1 - 4.8e-10 40.1 0.0 7.8e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 PSC70020.1 - 0.00052 19.9 0.0 0.00081 19.3 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase PCMT PF01135.19 PSC70020.1 - 0.00055 19.8 0.0 0.00086 19.1 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 PSC70020.1 - 0.0072 15.9 0.0 0.015 14.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain AT_hook PF02178.19 PSC70021.1 - 1.1 9.3 37.2 0.76 9.8 4.0 5.4 4 0 0 4 4 4 0 AT hook motif THOC7 PF05615.13 PSC70022.1 - 4.8e-21 75.4 8.4 4.8e-21 75.4 8.4 1.8 1 1 1 2 2 2 1 Tho complex subunit 7 DUF724 PF05266.14 PSC70022.1 - 0.0093 15.8 11.3 0.034 14.0 11.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF724) IFT57 PF10498.9 PSC70022.1 - 0.015 14.3 8.8 0.011 14.7 7.6 1.4 1 1 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4407 PF14362.6 PSC70022.1 - 0.028 13.8 20.5 0.072 12.4 20.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3584 PF12128.8 PSC70022.1 - 0.082 10.4 16.4 0.094 10.2 16.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Atg14 PF10186.9 PSC70022.1 - 0.39 9.7 8.5 0.53 9.3 8.5 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM76 PF16046.5 PSC70022.1 - 0.79 9.0 5.0 1 8.6 5.0 1.2 1 0 0 1 1 1 0 FAM76 protein Spc7 PF08317.11 PSC70022.1 - 1.6 7.5 18.2 3.9 6.3 17.7 1.7 1 1 0 1 1 1 0 Spc7 kinetochore protein TMPIT PF07851.13 PSC70022.1 - 2 7.6 6.0 2.5 7.3 6.0 1.3 1 0 0 1 1 1 0 TMPIT-like protein V_ATPase_I PF01496.19 PSC70022.1 - 2.6 5.8 9.0 3.2 5.6 9.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cnn_1N PF07989.11 PSC70022.1 - 4.1 7.6 8.1 1.2 9.3 2.5 2.6 1 1 0 2 2 2 0 Centrosomin N-terminal motif 1 THOC7 PF05615.13 PSC70023.1 - 6.9e-21 74.9 8.5 6.9e-21 74.9 8.5 1.6 1 1 1 2 2 2 1 Tho complex subunit 7 DUF724 PF05266.14 PSC70023.1 - 0.01 15.7 10.8 0.042 13.7 10.8 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) IFT57 PF10498.9 PSC70023.1 - 0.016 14.2 8.3 0.022 13.8 8.3 1.2 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 DUF4407 PF14362.6 PSC70023.1 - 0.18 11.1 20.5 0.49 9.7 20.4 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 PSC70023.1 - 0.3 10.1 7.4 0.4 9.7 7.4 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ERM PF00769.19 PSC70023.1 - 0.59 9.9 20.4 0.84 9.4 20.4 1.3 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF3584 PF12128.8 PSC70023.1 - 0.71 7.3 18.8 0.87 7.0 18.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) FAM76 PF16046.5 PSC70023.1 - 0.95 8.8 5.0 1.2 8.4 5.0 1.2 1 0 0 1 1 1 0 FAM76 protein Spc7 PF08317.11 PSC70023.1 - 2.9 6.7 18.0 7.7 5.3 17.9 1.5 1 1 1 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 PSC70023.1 - 2.9 5.7 8.6 3.8 5.3 8.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Cnn_1N PF07989.11 PSC70023.1 - 5.8 7.2 8.1 1.5 9.0 2.6 2.5 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 TMPIT PF07851.13 PSC70023.1 - 8.2 5.6 7.6 11 5.2 7.6 1.2 1 0 0 1 1 1 0 TMPIT-like protein HABP4_PAI-RBP1 PF04774.15 PSC70024.1 - 3.2e-07 31.2 5.1 2.6e-05 25.0 5.1 2.1 1 1 0 1 1 1 1 Hyaluronan / mRNA binding family DIOX_N PF14226.6 PSC70026.1 - 6.7e-32 110.7 0.0 9.9e-32 110.2 0.0 1.2 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 PSC70026.1 - 3.5e-22 78.8 0.0 6e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Helicase_C PF00271.31 PSC70027.1 - 0.016 15.5 0.1 0.022 15.1 0.1 1.2 1 0 0 1 1 1 0 Helicase conserved C-terminal domain Glyco_transf_49 PF13896.6 PSC70030.1 - 7.3e-43 147.2 1.5 2.5e-41 142.1 1.5 2.1 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 PSC70030.1 - 0.16 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 Polysacc_synt_4 PF04669.13 PSC70031.1 - 6.8e-23 81.2 0.0 1.7e-21 76.7 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis zf-NF-X1 PF01422.17 PSC70031.1 - 1.3 9.2 4.3 2.8 8.1 4.3 1.5 1 0 0 1 1 1 0 NF-X1 type zinc finger Polysacc_synt_4 PF04669.13 PSC70032.1 - 6.8e-23 81.2 0.0 1.7e-21 76.7 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis zf-NF-X1 PF01422.17 PSC70032.1 - 1.3 9.2 4.3 2.8 8.1 4.3 1.5 1 0 0 1 1 1 0 NF-X1 type zinc finger TraB PF01963.17 PSC70033.1 - 6.6e-20 72.1 0.2 1.5e-10 41.4 0.1 2.1 2 0 0 2 2 2 2 TraB family Senescence PF06911.12 PSC70034.1 - 3e-23 83.1 6.7 3e-23 83.1 6.7 4.4 2 1 2 4 4 4 1 Senescence-associated protein Glyco_transf_49 PF13896.6 PSC70035.1 - 1.4e-41 142.9 4.1 8.6e-41 140.4 0.2 2.7 2 1 0 2 2 2 1 Glycosyl-transferase for dystroglycan DUF2722 PF10846.8 PSC70035.1 - 0.0062 15.5 0.7 0.0075 15.3 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Glycos_transf_2 PF00535.26 PSC70035.1 - 0.19 11.5 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 Spt20 PF12090.8 PSC70035.1 - 0.47 10.0 10.3 0.73 9.4 10.3 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 PSC70035.1 - 0.66 10.1 12.5 1.6 8.8 12.5 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Glyco_transf_49 PF13896.6 PSC70036.1 - 1.2e-41 143.1 4.0 8e-41 140.5 0.1 2.7 2 1 0 2 2 2 1 Glycosyl-transferase for dystroglycan DUF2722 PF10846.8 PSC70036.1 - 0.0063 15.5 0.7 0.0075 15.3 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Glycos_transf_2 PF00535.26 PSC70036.1 - 0.18 11.6 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 Spt20 PF12090.8 PSC70036.1 - 0.47 10.0 10.3 0.73 9.4 10.3 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 PSC70036.1 - 0.66 10.1 12.5 1.6 8.8 12.5 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CoA_transf_3 PF02515.17 PSC70037.1 - 3.2e-109 365.4 0.1 4e-109 365.1 0.1 1.1 1 0 0 1 1 1 1 CoA-transferase family III HGTP_anticodon PF03129.20 PSC70038.1 - 7.3e-10 38.9 0.5 1.7e-09 37.7 0.1 1.9 2 0 0 2 2 2 1 Anticodon binding domain GTP-bdg_N PF13167.6 PSC70039.1 - 1.8e-31 108.7 0.0 4e-31 107.5 0.0 1.6 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 PSC70039.1 - 2.6e-28 98.4 7.8 5.8e-28 97.3 7.8 1.6 1 0 0 1 1 1 1 GTP-binding GTPase Middle Region MMR_HSR1 PF01926.23 PSC70039.1 - 6.9e-21 74.5 0.0 5.7e-20 71.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PSC70039.1 - 1.2e-05 25.4 0.1 0.00032 20.8 0.0 2.2 1 1 1 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 PSC70039.1 - 0.00081 19.3 0.0 0.027 14.4 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 PSC70039.1 - 0.0026 18.3 0.0 0.035 14.6 0.0 2.5 2 1 1 3 3 3 1 ABC transporter FeoB_N PF02421.18 PSC70039.1 - 0.0041 16.7 0.1 0.0083 15.7 0.1 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_Xtn PF16897.5 PSC70039.1 - 0.0075 16.3 0.0 0.015 15.3 0.0 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain AAA_16 PF13191.6 PSC70039.1 - 0.035 14.5 0.0 0.091 13.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Aa_trans PF01490.18 PSC70040.1 - 4.4e-33 114.6 21.5 6.6e-33 114.0 21.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Aa_trans PF01490.18 PSC70041.1 - 6.5e-32 110.7 20.4 9.7e-32 110.2 20.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SH3_3 PF08239.11 PSC70042.1 - 2.5e-05 24.5 0.0 7.1e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Bacterial SH3 domain Tmemb_161AB PF10268.9 PSC70042.1 - 0.00019 20.2 1.0 0.00019 20.2 1.0 2.3 1 1 1 2 2 2 1 Predicted transmembrane protein 161AB FBPase PF00316.20 PSC70046.1 - 1.4e-70 236.6 0.0 1.9e-70 236.2 0.0 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain CTP_transf_like PF01467.26 PSC70048.1 - 8.2e-30 103.9 0.0 1.4e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 Cytidylyltransferase-like PAP2 PF01569.21 PSC70048.1 - 2.6e-19 69.3 8.2 5.5e-19 68.3 7.2 2.0 2 0 0 2 2 2 1 PAP2 superfamily DUF563 PF04577.14 PSC70048.1 - 4.8e-08 33.4 0.0 2.1e-07 31.3 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF563) PAP2_3 PF14378.6 PSC70048.1 - 3.4e-07 30.1 9.3 6.3e-07 29.3 9.3 1.4 1 0 0 1 1 1 1 PAP2 superfamily DUF5639 PF18690.1 PSC70048.1 - 0.087 13.0 0.0 0.3 11.3 0.0 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5639) PAP2_C PF14360.6 PSC70048.1 - 0.15 12.6 0.2 0.31 11.6 0.2 1.4 1 0 0 1 1 1 0 PAP2 superfamily C-terminal RPN1_RPN2_N PF17781.1 PSC70049.1 - 1.3e-112 376.3 0.0 1.9e-112 375.7 0.0 1.2 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 PSC70049.1 - 3.4e-31 107.1 0.2 7.1e-31 106.0 0.2 1.6 1 0 0 1 1 1 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 PSC70049.1 - 6.1e-17 61.1 23.5 2.1e-06 27.8 0.1 9.0 11 0 0 11 11 11 3 Proteasome/cyclosome repeat HEAT_2 PF13646.6 PSC70049.1 - 1.8e-09 37.8 11.1 0.00036 20.8 0.0 5.2 4 3 1 5 5 5 2 HEAT repeats HEAT PF02985.22 PSC70049.1 - 0.23 11.8 2.8 4 8.0 0.0 4.4 7 0 0 7 7 7 0 HEAT repeat Senescence PF06911.12 PSC70050.1 - 0.035 14.4 0.6 0.49 10.7 0.5 2.2 1 1 0 1 1 1 0 Senescence-associated protein Ank_5 PF13857.6 PSC70051.1 - 2.5e-29 101.0 8.2 2.7e-09 37.1 0.0 5.7 2 2 4 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC70051.1 - 4.1e-29 100.6 10.0 1.4e-09 38.3 0.0 4.5 2 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 PSC70051.1 - 4.4e-29 100.9 3.5 1.6e-13 51.0 0.0 4.1 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PSC70051.1 - 4.4e-23 78.9 7.0 0.00013 22.1 0.0 7.6 7 0 0 7 7 7 5 Ankyrin repeat Ank PF00023.30 PSC70051.1 - 1.7e-19 69.3 15.0 0.00049 20.4 0.3 6.0 4 1 1 5 5 5 5 Ankyrin repeat zf-GRF PF06839.12 PSC70051.1 - 4.7e-12 45.8 0.4 4.7e-12 45.8 0.4 1.7 2 0 0 2 2 2 1 GRF zinc finger Exo_endo_phos PF03372.23 PSC70051.1 - 7.1e-11 42.1 0.1 2e-10 40.6 0.1 1.8 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Spt20 PF12090.8 PSC70051.1 - 0.24 11.0 4.0 0.4 10.3 4.0 1.2 1 0 0 1 1 1 0 Spt20 family DLIC PF05783.11 PSC70051.1 - 5 5.8 10.0 0.051 12.4 0.8 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Sulfotransfer_2 PF03567.14 PSC70052.1 - 1.7e-12 47.8 1.4 2.6e-12 47.2 1.4 1.2 1 0 0 1 1 1 1 Sulfotransferase family HrpJ PF07201.11 PSC70052.1 - 0.11 12.9 2.0 0.2 12.0 2.0 1.3 1 0 0 1 1 1 0 HrpJ-like domain Sulfotransfer_3 PF13469.6 PSC70052.1 - 0.13 12.6 0.0 0.44 10.9 0.0 1.9 2 1 0 2 2 2 0 Sulfotransferase family Ribosomal_60s PF00428.19 PSC70052.1 - 0.5 11.0 14.7 1.2 9.8 5.9 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Abhydrolase_9_N PF15420.6 PSC70052.1 - 1.7 8.6 7.9 0.043 13.8 1.2 1.7 3 0 0 3 3 3 0 Alpha/beta-hydrolase family N-terminus 5_3_exonuc_N PF02739.16 PSC70053.1 - 1.3e-43 148.7 0.0 1.7e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 PSC70053.1 - 2e-26 92.4 0.0 3.7e-26 91.5 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold HHH_5 PF14520.6 PSC70053.1 - 0.00061 20.4 0.2 0.002 18.7 0.0 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH_2 PF12826.7 PSC70053.1 - 0.13 12.4 0.0 0.35 11.0 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif HHH PF00633.23 PSC70053.1 - 0.15 12.0 0.5 0.55 10.2 0.1 2.2 2 0 0 2 2 2 0 Helix-hairpin-helix motif E1-N PF14463.6 PSC70053.1 - 0.23 11.3 3.7 0.59 9.9 3.7 1.6 1 0 0 1 1 1 0 E1 N-terminal domain DUF563 PF04577.14 PSC70054.1 - 1.7e-10 41.4 0.0 2e-10 41.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF563) LRR_4 PF12799.7 PSC70055.1 - 6.3e-09 36.0 0.2 0.43 11.1 0.0 7.2 7 1 1 8 8 8 2 Leucine Rich repeats (2 copies) F-box PF00646.33 PSC70055.1 - 0.00023 21.0 0.0 0.00067 19.5 0.0 1.8 1 0 0 1 1 1 1 F-box domain LRR_6 PF13516.6 PSC70055.1 - 0.001 18.9 33.2 0.45 10.7 0.1 9.5 12 0 0 12 12 12 4 Leucine Rich repeat LRR_1 PF00560.33 PSC70055.1 - 0.0022 18.3 6.8 27 5.8 0.0 6.8 9 0 0 9 9 9 1 Leucine Rich Repeat Herpes_capsid PF06112.11 PSC70055.1 - 1 9.4 12.0 0.087 12.9 3.9 2.5 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein PsbP PF01789.16 PSC70057.1 - 0.11 12.6 0.1 0.16 12.1 0.1 1.1 1 0 0 1 1 1 0 PsbP zf-RING_2 PF13639.6 PSC70058.1 - 9e-09 35.5 7.4 1.5e-08 34.8 7.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PSC70058.1 - 5e-05 23.1 2.9 0.0001 22.1 3.0 1.5 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PSC70058.1 - 9.7e-05 22.0 9.2 9.7e-05 22.0 9.2 1.6 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 PSC70058.1 - 0.00033 20.5 5.2 0.00055 19.8 5.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 PSC70058.1 - 0.00042 20.5 11.7 0.0013 18.9 10.9 2.2 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 PSC70058.1 - 0.0022 18.0 4.4 0.003 17.6 3.6 1.6 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 PSC70058.1 - 0.0045 17.0 3.5 0.0045 17.0 3.5 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PSC70058.1 - 0.015 15.1 3.1 0.015 15.1 3.1 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC70058.1 - 0.087 12.7 3.3 0.19 11.6 3.3 1.5 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.7 PSC70058.1 - 0.54 10.4 3.7 1.4 9.1 3.7 1.7 1 1 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 PSC70058.1 - 1.1 9.2 7.1 2.7 7.9 7.1 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 PSC70058.1 - 3.5 7.9 7.2 11 6.3 7.2 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain CPSase_L_D2 PF02786.17 PSC70059.1 - 7e-79 264.2 0.2 1.6e-78 263.0 0.1 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PYC_OADA PF02436.18 PSC70059.1 - 9.3e-67 224.6 0.0 1.6e-66 223.9 0.0 1.4 1 0 0 1 1 1 1 Conserved carboxylase domain Biotin_carb_C PF02785.19 PSC70059.1 - 8e-37 125.6 0.0 1.8e-36 124.5 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_carb_N PF00289.22 PSC70059.1 - 3.3e-36 124.2 0.0 7.1e-36 123.1 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain HMGL-like PF00682.19 PSC70059.1 - 3.8e-32 111.9 0.0 7.8e-32 110.9 0.0 1.6 1 0 0 1 1 1 1 HMGL-like Biotin_lipoyl PF00364.22 PSC70059.1 - 8.9e-15 54.3 1.4 2.1e-14 53.1 1.4 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 PSC70059.1 - 7.2e-09 35.4 0.0 1.4e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 PSC70059.1 - 6.1e-08 32.4 0.0 1.2e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 PSC70059.1 - 1.7e-05 24.6 0.2 0.02 14.7 0.0 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like ATP-grasp_3 PF02655.14 PSC70059.1 - 2.7e-05 24.3 0.0 5.7e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_Ter PF15632.6 PSC70059.1 - 0.0038 17.0 0.1 0.014 15.2 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon DUF3182 PF11379.8 PSC70059.1 - 0.0066 15.5 0.1 0.013 14.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3182) HlyD_D23 PF16576.5 PSC70059.1 - 0.029 13.6 0.2 4.5 6.4 0.1 2.3 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 PSC70059.1 - 0.06 12.9 0.0 0.46 10.1 0.0 2.3 2 0 0 2 2 2 0 ATP-grasp domain Aldolase_II PF00596.21 PSC70059.1 - 0.072 13.0 0.2 0.18 11.7 0.2 1.6 1 0 0 1 1 1 0 Class II Aldolase and Adducin N-terminal domain HlyD_3 PF13437.6 PSC70059.1 - 0.16 12.7 0.6 4 8.2 0.2 2.9 2 1 1 3 3 3 0 HlyD family secretion protein TRAPP PF04051.16 PSC70060.1 - 2.6e-39 134.2 0.1 3e-39 134.1 0.1 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component C_GCAxxG_C_C PF09719.10 PSC70060.1 - 0.019 15.3 1.1 0.7 10.2 0.2 2.2 1 1 0 2 2 2 0 Putative redox-active protein (C_GCAxxG_C_C) HrpB7 PF09486.10 PSC70061.1 - 0.01 16.2 2.8 0.01 16.2 2.8 2.1 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF3135 PF11333.8 PSC70061.1 - 0.049 13.9 3.0 0.1 12.8 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3135) GIT_CC PF16559.5 PSC70061.1 - 0.25 11.2 2.4 0.44 10.5 2.4 1.3 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor EF-hand_6 PF13405.6 PSC70062.1 - 1.8e-05 24.3 0.5 0.061 13.3 0.1 3.4 4 0 0 4 4 3 2 EF-hand domain EF-hand_5 PF13202.6 PSC70062.1 - 0.00063 19.1 8.1 0.19 11.3 0.3 3.5 4 0 0 4 4 3 2 EF hand EF-hand_1 PF00036.32 PSC70062.1 - 0.00065 19.1 0.2 1.6 8.5 0.1 3.2 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 PSC70062.1 - 0.00071 20.0 0.0 1.2 9.6 0.0 3.0 2 1 0 2 2 2 1 EF-hand domain pair Spc7 PF08317.11 PSC70062.1 - 0.0008 18.4 11.0 0.0008 18.4 11.0 2.0 1 1 1 2 2 2 1 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 PSC70062.1 - 0.013 15.6 4.2 0.013 15.6 4.2 2.7 1 1 0 2 2 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.12 PSC70062.1 - 0.025 14.6 0.1 0.048 13.7 0.1 1.4 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3450 PF11932.8 PSC70062.1 - 0.027 13.8 19.9 0.044 13.1 12.1 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) UvrD_C PF13361.6 PSC70062.1 - 0.047 13.1 0.0 0.062 12.7 0.0 1.2 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain EF-hand_8 PF13833.6 PSC70062.1 - 0.11 12.4 0.2 75 3.3 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain pair DUF812 PF05667.11 PSC70062.1 - 0.29 9.9 11.2 0.42 9.4 11.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SHE3 PF17078.5 PSC70062.1 - 0.33 10.6 1.4 0.64 9.7 0.2 1.7 1 1 0 1 1 1 0 SWI5-dependent HO expression protein 3 Gp-FAR-1 PF05823.12 PSC70062.1 - 0.36 11.2 6.1 0.14 12.5 0.8 2.3 1 1 1 2 2 2 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ADIP PF11559.8 PSC70062.1 - 0.73 9.9 14.2 0.086 12.9 3.9 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding EzrA PF06160.12 PSC70062.1 - 1 7.5 9.7 2.1 6.4 0.3 2.0 2 0 0 2 2 2 0 Septation ring formation regulator, EzrA FTA4 PF13093.6 PSC70062.1 - 1.1 9.1 5.1 1.7 8.5 4.4 1.5 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 BLOC1_2 PF10046.9 PSC70062.1 - 1.3 9.4 6.7 6.9 7.1 0.6 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Muted PF14942.6 PSC70062.1 - 2.3 8.6 5.9 5.1 7.4 5.9 1.5 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein Syntaxin-6_N PF09177.11 PSC70062.1 - 2.4 8.8 5.1 4.8 7.8 0.9 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal UPF0242 PF06785.11 PSC70062.1 - 2.6 8.1 9.0 4.1 7.5 9.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF5082 PF16888.5 PSC70062.1 - 3.4 8.0 7.4 7.4 6.9 1.2 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF5082) Seryl_tRNA_N PF02403.22 PSC70062.1 - 5.8 7.2 16.0 0.13 12.5 5.7 2.7 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Metalloenzyme PF01676.18 PSC70063.1 - 5e-81 271.7 0.0 6.1e-81 271.4 0.0 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 PSC70063.1 - 1.9e-32 112.5 0.3 9.8e-19 67.7 0.1 2.3 1 1 1 2 2 2 2 BPG-independent PGAM N-terminus (iPGM_N) Phosphodiest PF01663.22 PSC70063.1 - 0.0052 16.4 0.0 0.013 15.1 0.0 1.6 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase DUF3659 PF12396.8 PSC70063.1 - 0.076 12.9 0.5 0.24 11.3 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) PglZ PF08665.12 PSC70063.1 - 0.12 12.5 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 PglZ domain Gp_dh_C PF02800.20 PSC70064.1 - 3.9e-70 234.5 0.0 7.1e-70 233.7 0.0 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 PSC70064.1 - 2.5e-39 133.7 0.0 7e-39 132.3 0.0 1.8 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 PSC70064.1 - 0.0085 16.2 0.0 0.022 14.9 0.0 1.8 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 PSC70064.1 - 0.056 12.8 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_24 PF13578.6 PSC70066.1 - 3.4e-13 50.5 0.0 4.8e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.25 PSC70067.1 - 2.2e-23 82.7 0.0 2.5e-12 46.6 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PSC70067.1 - 3.7e-20 72.5 0.0 2.4e-10 40.4 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 PSC70067.1 - 5.6e-05 22.7 0.1 0.0075 15.8 0.0 2.4 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PSC70067.1 - 0.00011 22.1 5.6 0.23 11.3 0.1 3.9 4 0 0 4 4 4 2 NAD(P)H-binding KR PF08659.10 PSC70067.1 - 0.004 17.1 0.2 0.61 10.0 0.0 3.3 4 0 0 4 4 4 1 KR domain THF_DHG_CYH_C PF02882.19 PSC70067.1 - 0.0048 16.2 0.1 1.8 7.8 0.0 2.3 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 3HCDH_N PF02737.18 PSC70067.1 - 0.072 13.0 0.1 2.9 7.7 0.0 2.4 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NmrA PF05368.13 PSC70067.1 - 0.074 12.6 0.3 1.7 8.2 0.0 2.4 2 0 0 2 2 2 0 NmrA-like family GDP_Man_Dehyd PF16363.5 PSC70067.1 - 0.14 11.5 0.0 1.2 8.5 0.0 2.2 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Glyco_transf_92 PF01697.27 PSC70070.1 - 8.1e-08 32.2 0.0 0.0011 18.7 0.0 2.9 2 1 0 3 3 3 2 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PSC70070.1 - 1.3e-06 28.8 0.0 1.2e-05 25.7 0.0 2.3 1 1 0 1 1 1 1 Glycosyl transferase family 2 DUF1180 PF06679.12 PSC70070.1 - 0.19 12.1 1.7 0.35 11.3 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DNA_ligase_A_M PF01068.21 PSC70071.1 - 1.7e-40 138.9 0.0 5.1e-31 107.9 0.0 2.4 2 0 0 2 2 2 2 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 PSC70071.1 - 6.5e-35 121.0 0.0 1.4e-34 119.9 0.0 1.6 1 0 0 1 1 1 1 DNA ligase N terminus MIF PF01187.18 PSC70071.1 - 4.6e-27 94.6 0.0 9.4e-27 93.6 0.0 1.5 1 0 0 1 1 1 1 Macrophage migration inhibitory factor (MIF) DNA_ligase_A_C PF04679.15 PSC70071.1 - 3.2e-22 79.0 0.0 1.3e-21 77.1 0.0 2.1 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region DRMBL PF07522.14 PSC70071.1 - 1.9e-18 66.6 0.0 3.3e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 PSC70071.1 - 2e-11 43.8 0.1 2e-11 43.8 0.1 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain DUF4376 PF14301.6 PSC70071.1 - 0.0034 17.7 0.1 0.014 15.7 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4376) CBM_20 PF00686.19 PSC70071.1 - 0.0072 16.2 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Starch binding domain DUF2052 PF09747.9 PSC70071.1 - 0.01 16.0 0.8 0.024 14.7 0.8 1.6 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Lactamase_B PF00753.27 PSC70071.1 - 0.021 14.9 1.6 0.081 12.9 1.0 2.3 2 0 0 2 2 2 0 Metallo-beta-lactamase superfamily mRNA_cap_enzyme PF01331.19 PSC70071.1 - 0.037 13.9 0.0 0.83 9.4 0.0 2.5 2 0 0 2 2 2 0 mRNA capping enzyme, catalytic domain Tautomerase PF01361.21 PSC70071.1 - 0.045 13.7 0.2 7.6 6.5 0.0 3.6 4 0 0 4 4 4 0 Tautomerase enzyme RMMBL PF07521.12 PSC70071.1 - 0.096 12.6 0.0 0.28 11.2 0.0 1.8 1 0 0 1 1 1 0 Zn-dependent metallo-hydrolase RNA specificity domain HD PF01966.22 PSC70072.1 - 1.7e-16 60.5 0.5 8e-16 58.4 0.2 2.1 2 0 0 2 2 2 1 HD domain Pyridox_oxase_2 PF12766.7 PSC70073.1 - 2.4e-30 105.1 0.0 3.3e-30 104.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 PSC70073.1 - 1.1e-11 44.8 0.0 1.6e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 PSC70073.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like Pyridox_oxase_2 PF12766.7 PSC70074.1 - 2.7e-30 104.9 0.0 3.7e-30 104.5 0.0 1.2 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 PSC70074.1 - 1.1e-11 44.8 0.0 1.6e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 PSC70074.1 - 0.018 14.7 0.0 0.026 14.1 0.0 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like Mannosyl_trans3 PF11051.8 PSC70075.1 - 1.8e-24 86.6 0.0 1.1e-13 51.2 0.0 2.1 1 1 1 2 2 2 2 Mannosyltransferase putative 2OG-FeII_Oxy_2 PF13532.6 PSC70075.1 - 2.5e-07 31.1 0.0 4.5e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Acyltransferase PF01553.21 PSC70078.1 - 1.6e-08 34.2 0.0 5.3e-08 32.6 0.0 1.8 2 0 0 2 2 2 1 Acyltransferase MRP-S26 PF14943.6 PSC70078.1 - 2.8e-05 24.1 16.9 0.00026 20.9 4.1 2.2 1 1 1 2 2 2 2 Mitochondrial ribosome subunit S26 FAM216B PF15107.6 PSC70078.1 - 0.076 12.9 0.6 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 FAM216B protein family Glyco_transf_49 PF13896.6 PSC70079.1 - 7.3e-43 147.2 1.5 2.5e-41 142.1 1.5 2.1 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 PSC70079.1 - 0.16 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 MatE PF01554.18 PSC70081.1 - 5.4e-49 165.9 28.8 2e-29 102.3 8.4 2.5 2 0 0 2 2 2 2 MatE CAP_N PF01213.19 PSC70081.1 - 0.31 10.5 4.5 0.57 9.6 4.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 PSC70081.1 - 0.59 10.2 1.3 0.89 9.6 1.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Pkinase PF00069.25 PSC70082.1 - 4.2e-100 334.5 0.0 1.8e-50 171.7 0.0 2.6 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC70082.1 - 4.7e-98 327.6 0.0 2.9e-48 164.4 0.0 3.1 2 2 0 2 2 2 2 Protein tyrosine kinase LRR_4 PF12799.7 PSC70082.1 - 2.5e-23 81.7 9.2 0.023 15.1 0.0 8.8 6 2 2 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC70082.1 - 1.7e-21 75.7 15.6 0.002 17.8 0.0 8.7 7 1 1 8 8 8 6 Leucine rich repeat Kinase-like PF14531.6 PSC70082.1 - 5.7e-08 32.4 0.0 0.0062 15.9 0.0 2.2 2 0 0 2 2 2 2 Kinase-like LRR_1 PF00560.33 PSC70082.1 - 3.2e-07 30.0 8.7 16 6.5 0.2 10.2 11 0 0 11 11 11 1 Leucine Rich Repeat Kdo PF06293.14 PSC70082.1 - 8.9e-05 21.9 0.7 0.13 11.6 0.1 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_6 PF13516.6 PSC70082.1 - 0.0061 16.5 20.0 32 4.9 0.1 9.9 11 0 0 11 11 11 0 Leucine Rich repeat DUF4381 PF14316.6 PSC70082.1 - 0.0066 16.7 2.6 0.079 13.2 0.2 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4381) RIO1 PF01163.22 PSC70082.1 - 0.021 14.4 0.0 3.1 7.4 0.0 2.2 2 0 0 2 2 2 0 RIO1 family LRRNT_2 PF08263.12 PSC70082.1 - 0.098 13.0 9.9 2.4 8.6 0.6 3.7 3 0 0 3 3 2 0 Leucine rich repeat N-terminal domain EamA PF00892.20 PSC70083.1 - 0.0026 17.9 0.1 0.0043 17.2 0.1 1.3 1 0 0 1 1 1 1 EamA-like transporter family rve PF00665.26 PSC70085.1 - 9.6e-19 67.7 0.0 2.4e-18 66.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC70085.1 - 0.0088 15.8 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain AAA_25 PF13481.6 PSC70085.1 - 0.048 13.2 5.7 3.5 7.1 0.3 4.1 3 1 0 3 3 3 0 AAA domain PBP1_TM PF14812.6 PSC70085.1 - 0.05 14.0 3.4 3.5 8.0 1.4 3.3 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Alpha-amyl_C2 PF07821.12 PSC70086.1 - 9.1e-17 61.0 0.6 2.7e-16 59.5 0.1 2.0 2 0 0 2 2 2 1 Alpha-amylase C-terminal beta-sheet domain Alpha-amylase PF00128.24 PSC70086.1 - 1.5e-16 61.0 0.0 5.6e-15 55.7 0.0 2.8 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 PSC70086.1 - 0.001 17.4 0.0 0.0016 16.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 70 IFT57 PF10498.9 PSC70087.1 - 7.4e-05 21.9 3.5 7.4e-05 21.9 3.5 2.7 3 0 0 3 3 3 1 Intra-flagellar transport protein 57 DUF5320 PF17253.2 PSC70087.1 - 0.043 14.9 7.2 2 9.5 0.1 4.1 3 0 0 3 3 3 0 Family of unknown function (DUF5320) MYO10_CC PF16735.5 PSC70087.1 - 0.63 10.2 0.0 0.63 10.2 0.0 3.9 4 0 0 4 4 4 0 Unconventional myosin-X coiled coil domain Lebercilin PF15619.6 PSC70087.1 - 2.7 7.6 27.5 0.023 14.3 6.6 3.5 3 0 0 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease PKcGMP_CC PF16808.5 PSC70087.1 - 5 7.1 7.5 6.3 6.7 0.2 3.3 3 0 0 3 3 3 0 Coiled-coil N-terminus of cGMP-dependent protein kinase FAM76 PF16046.5 PSC70087.1 - 6.3 6.1 6.9 6.7 6.0 2.9 2.2 2 0 0 2 2 2 0 FAM76 protein DUF563 PF04577.14 PSC70088.1 - 5.5e-06 26.7 0.0 7e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Lin-8 PF03353.15 PSC70089.1 - 2.6 7.5 13.2 6.4 6.3 13.2 1.6 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIF_alpha PF05793.12 PSC70089.1 - 3 6.3 27.1 5.3 5.5 27.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DDHD PF02862.17 PSC70089.1 - 5.2 7.2 5.2 14 5.7 5.2 1.8 1 0 0 1 1 1 0 DDHD domain SAPS PF04499.15 PSC70089.1 - 9.3 4.9 14.0 15 4.2 14.0 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Lin-8 PF03353.15 PSC70090.1 - 2.7 7.5 13.2 6.3 6.3 13.2 1.6 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TFIIF_alpha PF05793.12 PSC70090.1 - 3 6.3 27.1 5.3 5.5 27.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DDHD PF02862.17 PSC70090.1 - 5.2 7.2 5.2 14 5.7 5.2 1.8 1 0 0 1 1 1 0 DDHD domain SAPS PF04499.15 PSC70090.1 - 7.5 5.2 13.7 12 4.5 13.7 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein NUDIX PF00293.28 PSC70091.1 - 0.034 14.2 0.2 0.27 11.3 0.2 2.4 1 1 0 1 1 1 0 NUDIX domain Metalloenzyme PF01676.18 PSC70092.1 - 5.1e-81 271.7 0.0 5.9e-81 271.5 0.0 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily iPGM_N PF06415.13 PSC70092.1 - 8.3e-58 195.4 0.0 1.3e-57 194.8 0.0 1.3 1 0 0 1 1 1 1 BPG-independent PGAM N-terminus (iPGM_N) DUF2868 PF11067.8 PSC70092.1 - 0.078 12.5 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) DUF1995 PF09353.10 PSC70093.1 - 6.7e-09 36.1 0.0 7.3e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) MlaE PF02405.16 PSC70094.1 - 1.8e-70 236.9 18.6 2.3e-70 236.6 18.6 1.1 1 0 0 1 1 1 1 Permease MlaE Fer4_5 PF12801.7 PSC70095.1 - 6.9e-12 45.1 29.0 1.5e-07 31.2 8.0 3.8 3 0 0 3 3 3 2 4Fe-4S binding domain Sigma54_activat PF00158.26 PSC70095.1 - 4.7e-07 29.7 0.0 9.9e-07 28.6 0.0 1.6 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 PSC70095.1 - 1.6e-05 25.0 0.0 4e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain Fer4 PF00037.27 PSC70095.1 - 0.0026 17.5 0.9 0.0092 15.8 0.9 2.0 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_16 PF13484.6 PSC70095.1 - 0.024 15.6 0.4 0.077 13.9 0.4 1.9 1 0 0 1 1 1 0 4Fe-4S double cluster binding domain Fer4_10 PF13237.6 PSC70095.1 - 0.028 14.5 0.3 0.1 12.7 0.3 1.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_6 PF12837.7 PSC70095.1 - 0.11 12.7 6.3 0.039 14.0 2.8 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.6 PSC70095.1 - 0.11 12.6 8.2 0.42 10.8 8.2 2.0 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 PSC70095.1 - 0.24 11.9 7.5 0.83 10.2 7.5 2.0 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 PSC70095.1 - 0.37 11.4 6.2 1.1 9.9 6.2 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 PSC70095.1 - 2 8.9 7.9 5.9 7.4 7.9 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_3 PF12798.7 PSC70095.1 - 4.2 8.5 8.7 3.6 8.7 4.9 2.8 2 0 0 2 2 2 0 4Fe-4S binding domain CBS PF00571.28 PSC70096.1 - 1e-11 45.1 0.2 5.2e-06 26.8 0.0 4.3 4 0 0 4 4 4 3 CBS domain HABP4_PAI-RBP1 PF04774.15 PSC70096.1 - 5.7e-09 36.8 3.0 5.7e-09 36.8 3.0 6.0 3 3 0 4 4 4 1 Hyaluronan / mRNA binding family BTK PF00779.19 PSC70097.1 - 0.0016 18.2 6.0 0.034 14.0 3.8 2.6 2 0 0 2 2 2 2 BTK motif CHORD PF04968.12 PSC70097.1 - 0.0095 16.6 10.7 0.026 15.2 1.0 2.7 1 1 1 2 2 2 2 CHORD LCIB_C_CA PF18599.1 PSC70098.1 - 2e-152 504.7 0.0 7.5e-75 251.0 0.0 2.8 3 0 0 3 3 3 2 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Resistin PF06954.11 PSC70098.1 - 0.01 16.4 4.4 3.5 8.3 0.4 2.9 2 0 0 2 2 2 0 Resistin Tugs PF17840.1 PSC70098.1 - 9.3 6.5 10.6 23 5.3 0.4 4.3 6 0 0 6 6 6 0 Tethering Ubl4a to BAGS domain rve PF00665.26 PSC70100.1 - 2.4e-17 63.2 0.0 5.2e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC70100.1 - 0.0029 17.4 0.0 0.0072 16.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain PAS_4 PF08448.10 PSC70100.1 - 0.0053 17.0 0.2 0.078 13.2 0.0 2.7 2 0 0 2 2 2 1 PAS fold rve PF00665.26 PSC70101.1 - 2.3e-17 63.3 0.0 5.2e-17 62.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC70101.1 - 0.0028 17.4 0.0 0.0072 16.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain PAS_4 PF08448.10 PSC70101.1 - 0.005 17.1 0.2 0.076 13.3 0.0 2.7 2 0 0 2 2 2 1 PAS fold RINGv PF12906.7 PSC70102.1 - 1.4e-07 31.5 6.3 2.6e-07 30.7 6.3 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 PSC70102.1 - 0.0042 17.4 6.6 0.0077 16.5 6.6 1.5 1 0 0 1 1 1 1 Ring finger domain NRBF2 PF08961.10 PSC70102.1 - 0.018 14.6 0.3 0.018 14.6 0.3 1.4 2 0 0 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator TSC22 PF01166.18 PSC70102.1 - 0.019 15.2 2.2 0.047 14.0 2.2 1.6 1 0 0 1 1 1 0 TSC-22/dip/bun family XdhC_C PF13478.6 PSC70102.1 - 0.023 15.2 0.6 0.045 14.3 0.6 1.5 1 1 0 1 1 1 0 XdhC Rossmann domain VIT1 PF01988.19 PSC70102.1 - 0.041 13.7 1.7 0.061 13.2 1.7 1.2 1 0 0 1 1 1 0 VIT family DUF874 PF05917.11 PSC70102.1 - 0.042 12.9 0.9 0.056 12.5 0.9 1.1 1 0 0 1 1 1 0 Helicobacter pylori protein of unknown function (DUF874) Zn_ribbon_17 PF17120.5 PSC70102.1 - 0.051 13.2 3.3 2.2 8.0 1.0 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 PSC70102.1 - 0.053 13.4 6.4 0.1 12.5 1.1 2.3 1 1 1 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 PSC70102.1 - 0.24 11.3 3.1 2.7 8.0 1.2 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Macoilin PF09726.9 PSC70102.1 - 1.6 7.2 7.8 2.1 6.8 7.8 1.1 1 0 0 1 1 1 0 Macoilin family ZapB PF06005.12 PSC70102.1 - 3 8.4 11.8 0.98 9.9 8.6 1.7 1 1 1 2 2 2 0 Cell division protein ZapB FANCL_C PF11793.8 PSC70102.1 - 4.1 7.7 7.6 1.8 8.8 2.8 2.5 1 1 1 2 2 2 0 FANCL C-terminal domain Syntaxin-18_N PF10496.9 PSC70103.1 - 8.2e-10 38.8 0.0 1.2e-08 35.1 0.0 2.7 3 0 0 3 3 3 1 SNARE-complex protein Syntaxin-18 N-terminus SNARE PF05739.19 PSC70103.1 - 4.9e-06 26.4 0.7 1.6e-05 24.8 0.1 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin-6_N PF09177.11 PSC70103.1 - 0.05 14.2 0.4 2 9.1 0.0 2.5 3 0 0 3 3 3 0 Syntaxin 6, N-terminal DUF2383 PF09537.10 PSC70103.1 - 0.06 13.7 1.6 3.8 7.9 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF2383) AAA_33 PF13671.6 PSC70104.1 - 4.3e-07 30.2 1.3 1.5e-06 28.4 0.0 2.4 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 PSC70104.1 - 2.6e-05 24.8 0.1 8.8e-05 23.1 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 PSC70104.1 - 0.00012 22.3 0.1 0.00012 22.3 0.1 2.4 3 0 0 3 3 2 1 AAA domain Zeta_toxin PF06414.12 PSC70104.1 - 0.00037 19.8 0.0 0.00082 18.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_16 PF13191.6 PSC70104.1 - 0.00058 20.3 0.1 0.00058 20.3 0.1 2.4 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PSC70104.1 - 0.0066 16.7 0.0 0.049 13.9 0.0 2.4 3 0 0 3 3 3 1 AAA domain PAC4 PF16093.5 PSC70104.1 - 0.0099 16.0 1.6 0.054 13.7 0.5 2.6 2 1 0 2 2 2 1 Proteasome assembly chaperone 4 AAA_5 PF07728.14 PSC70104.1 - 0.013 15.5 0.1 0.023 14.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA PF00004.29 PSC70104.1 - 0.013 15.9 0.0 0.023 15.1 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 PSC70104.1 - 0.022 14.6 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_29 PF13555.6 PSC70104.1 - 0.041 13.6 0.1 0.095 12.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RuvB_N PF05496.12 PSC70104.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain ABC_tran PF00005.27 PSC70104.1 - 0.063 13.8 0.0 0.15 12.6 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_25 PF13481.6 PSC70104.1 - 0.079 12.5 0.5 0.2 11.2 0.5 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 PSC70104.1 - 0.11 13.0 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase APS_kinase PF01583.20 PSC70104.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase TsaE PF02367.17 PSC70104.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 PSC70104.1 - 0.12 12.3 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain Cytidylate_kin PF02224.18 PSC70104.1 - 0.12 12.1 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Sigma54_activat PF00158.26 PSC70104.1 - 0.2 11.3 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain IMS PF00817.20 PSC70105.1 - 8.1e-71 236.9 0.0 1.3e-37 129.1 0.1 3.2 2 1 0 2 2 2 2 impB/mucB/samB family IMS_C PF11799.8 PSC70105.1 - 2.5e-14 54.0 0.0 1.1e-10 42.2 0.0 2.6 2 0 0 2 2 2 2 impB/mucB/samB family C-terminal domain IMS_HHH PF11798.8 PSC70105.1 - 0.0014 18.8 1.2 0.0025 18.1 0.0 2.1 2 0 0 2 2 2 1 IMS family HHH motif DUF1876 PF08962.11 PSC70105.1 - 0.0018 18.2 0.8 0.0095 15.9 0.8 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1876) EamA PF00892.20 PSC70106.1 - 5.6e-20 71.9 24.9 1.4e-11 44.7 7.9 2.5 2 0 0 2 2 2 2 EamA-like transporter family Herpes_UL95 PF03038.14 PSC70106.1 - 0.22 10.6 0.1 0.32 10.1 0.1 1.1 1 0 0 1 1 1 0 UL95 family MASE5 PF17178.4 PSC70106.1 - 2 8.2 7.4 0.71 9.7 3.9 1.9 2 0 0 2 2 2 0 Membrane-associated sensor Aha1_N PF09229.11 PSC70108.1 - 3.5e-37 127.7 0.0 5e-37 127.2 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 PSC70108.1 - 5.9e-18 65.3 0.0 1.2e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein TFIIS_M PF07500.14 PSC70109.1 - 2e-26 92.7 0.0 4.2e-26 91.6 0.0 1.6 1 1 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain SPOC PF07744.13 PSC70109.1 - 2.8e-10 40.3 0.0 1.1e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 SPOC domain SMN PF06003.12 PSC70109.1 - 0.0025 17.1 0.1 0.0079 15.5 0.1 1.8 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Ribosomal_60s PF00428.19 PSC70110.1 - 0.0003 21.3 12.3 0.00053 20.5 12.3 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein Pox_Ag35 PF03286.14 PSC70110.1 - 0.0094 15.8 3.2 0.011 15.5 3.2 1.1 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Vfa1 PF08432.10 PSC70110.1 - 0.33 11.3 2.5 0.41 10.9 2.5 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Spt5_N PF11942.8 PSC70110.1 - 0.77 10.8 15.0 1.1 10.2 15.0 1.2 1 0 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.14 PSC70110.1 - 0.85 7.8 8.8 0.97 7.7 8.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Nop53 PF07767.11 PSC70110.1 - 0.9 8.9 12.0 1.1 8.6 12.0 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DNA_pol_phi PF04931.13 PSC70110.1 - 1 7.3 10.8 1.1 7.3 10.8 1.0 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 PSC70110.1 - 1.3 8.7 8.6 1.6 8.4 8.6 1.2 1 0 0 1 1 1 0 FAM176 family COPI_C PF06957.11 PSC70110.1 - 2.1 7.0 6.0 2.3 6.9 6.0 1.1 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus Nop14 PF04147.12 PSC70110.1 - 2.2 6.4 10.2 2.4 6.2 10.2 1.0 1 0 0 1 1 1 0 Nop14-like family DUF3774 PF12609.8 PSC70110.1 - 2.3 9.3 7.0 39 5.4 7.0 2.1 1 1 0 1 1 1 0 Wound-induced protein NOA36 PF06524.12 PSC70110.1 - 2.5 7.4 8.6 3.5 6.9 8.6 1.2 1 0 0 1 1 1 0 NOA36 protein CENP-B_dimeris PF09026.10 PSC70110.1 - 3.4 8.1 9.0 4.8 7.6 9.0 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3381 PF11861.8 PSC70110.1 - 3.4 7.4 11.7 4.4 7.1 11.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF4637 PF15470.6 PSC70110.1 - 5.4 6.7 11.9 7.5 6.3 11.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Cytomega_UL84 PF06284.11 PSC70110.1 - 6.1 5.2 6.1 7.5 4.9 6.1 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein SLAC1 PF03595.17 PSC70111.1 - 7.8e-32 110.8 51.9 7.8e-32 110.8 51.9 2.3 2 1 0 2 2 2 1 Voltage-dependent anion channel Glutaredoxin PF00462.24 PSC70111.1 - 3.1e-31 107.4 0.1 7.1e-16 58.2 0.0 2.5 2 0 0 2 2 2 2 Glutaredoxin DUF4395 PF14340.6 PSC70111.1 - 2e-18 67.0 13.2 2e-18 67.0 13.2 4.2 3 1 0 4 4 4 1 Domain of unknown function (DUF4395) GST_N_3 PF13417.6 PSC70111.1 - 2.3e-10 40.7 0.0 9e-05 22.8 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PSC70111.1 - 2.5e-06 27.7 0.0 0.11 12.8 0.0 2.8 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain DUF3090 PF11290.8 PSC70111.1 - 0.04 13.7 0.4 11 5.7 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) Thioredoxin_2 PF13098.6 PSC70111.1 - 0.046 14.2 0.0 17 5.9 0.0 2.6 2 0 0 2 2 2 0 Thioredoxin-like domain DUF836 PF05768.14 PSC70111.1 - 0.13 12.7 0.0 5.2 7.6 0.0 2.4 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) Gpr1_Fun34_YaaH PF01184.19 PSC70112.1 - 5.6e-73 244.9 34.9 2.1e-36 125.5 13.6 2.2 2 0 0 2 2 2 2 GPR1/FUN34/yaaH family Rhodanese PF00581.20 PSC70112.1 - 1.1e-44 151.3 0.0 1.1e-13 51.6 0.0 3.5 3 0 0 3 3 3 3 Rhodanese-like domain Pro_isomerase PF00160.21 PSC70113.1 - 4.1e-15 56.4 0.0 8.4e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Pro_isomerase PF00160.21 PSC70114.1 - 4.1e-15 56.4 0.0 8.4e-15 55.4 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K_trans PF02705.16 PSC70115.1 - 6.6e-176 585.9 19.8 7.9e-176 585.7 19.8 1.1 1 0 0 1 1 1 1 K+ potassium transporter K_trans PF02705.16 PSC70116.1 - 2.3e-176 587.5 19.9 2.7e-176 587.2 19.9 1.1 1 0 0 1 1 1 1 K+ potassium transporter Aminoglyc_resit PF10706.9 PSC70118.1 - 0.079 12.7 0.2 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 Aminoglycoside-2''-adenylyltransferase FGGY_N PF00370.21 PSC70118.1 - 0.18 11.3 0.0 1.2 8.7 0.0 1.9 2 0 0 2 2 2 0 FGGY family of carbohydrate kinases, N-terminal domain DUF2258 PF10015.9 PSC70118.1 - 0.19 11.9 0.1 0.37 11.0 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2258) DUF2095 PF09868.9 PSC70120.1 - 0.027 14.5 0.1 0.027 14.4 0.1 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2095) G6PD_C PF02781.16 PSC70121.1 - 1.5e-113 378.8 0.0 1.9e-113 378.5 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 PSC70121.1 - 2.2e-51 175.0 0.0 3.4e-51 174.4 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Arm PF00514.23 PSC70122.1 - 0.0041 17.1 0.2 0.014 15.4 0.1 2.1 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat SAC3_GANP PF03399.16 PSC70123.1 - 5.2e-08 32.6 0.0 8.1e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 PSC70123.1 - 0.00028 20.9 0.0 0.00053 20.0 0.0 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Fer2 PF00111.27 PSC70124.1 - 5.9e-19 67.8 0.9 5.9e-19 67.8 0.9 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain RINGv PF12906.7 PSC70124.1 - 1.2e-12 47.7 10.4 3.1e-12 46.4 10.4 1.7 1 0 0 1 1 1 1 RING-variant domain Fer2_4 PF13510.6 PSC70124.1 - 0.36 10.9 2.8 0.69 10.0 0.0 2.6 2 1 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain FANCL_C PF11793.8 PSC70124.1 - 3 8.1 10.4 0.29 11.4 4.6 2.3 2 0 0 2 2 2 0 FANCL C-terminal domain Pmp3 PF01679.17 PSC70125.1 - 1.6e-18 66.6 6.5 4e-18 65.3 6.5 1.7 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TFIIA PF03153.13 PSC70127.1 - 0.5 10.3 15.7 0.63 10.0 15.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 PSC70127.1 - 0.63 9.6 11.8 0.95 9.0 11.8 1.2 1 0 0 1 1 1 0 Spt20 family T3SS_TC PF06511.11 PSC70127.1 - 1.4 8.2 9.0 1.9 7.8 9.0 1.1 1 0 0 1 1 1 0 Type III secretion systems tip complex components Suf PF05843.14 PSC70127.1 - 1.5 8.8 5.9 1.9 8.4 5.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Peptidase_S8 PF00082.22 PSC70128.1 - 6.8e-28 97.8 0.6 6.8e-28 97.8 0.6 2.1 2 0 0 2 2 2 1 Subtilase family MPP6 PF10175.9 PSC70128.1 - 4.6e-11 43.4 0.6 2.6e-10 40.9 0.3 2.3 1 1 0 1 1 1 1 M-phase phosphoprotein 6 APH PF01636.23 PSC70130.1 - 4e-44 151.3 0.1 4e-44 151.3 0.1 3.1 3 1 0 3 3 3 1 Phosphotransferase enzyme family Acyl-CoA_dh_1 PF00441.24 PSC70130.1 - 2.6e-33 115.3 3.3 5.2e-33 114.4 3.3 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 PSC70130.1 - 4.4e-16 58.9 0.0 7.6e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 PSC70130.1 - 1.9e-10 41.1 6.6 1.9e-10 41.1 6.6 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PSC70130.1 - 1.5e-07 32.0 3.5 3.8e-07 30.8 0.6 3.1 3 1 0 3 3 3 1 Acyl-CoA dehydrogenase, N-terminal domain PSI_8 PF00796.18 PSC70132.1 - 6.7 6.6 7.2 17 5.4 1.0 2.7 2 0 0 2 2 2 0 Photosystem I reaction centre subunit VIII DUF2344 PF10105.9 PSC70134.1 - 0.075 12.9 2.2 0.11 12.3 2.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) z-alpha PF02295.17 PSC70135.1 - 0.13 12.3 0.0 4.9 7.3 0.0 2.5 2 0 0 2 2 2 0 Adenosine deaminase z-alpha domain ECH_1 PF00378.20 PSC70136.1 - 4.3e-74 249.0 0.0 5.6e-74 248.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PSC70136.1 - 1.2e-18 67.7 0.0 2.9e-18 66.5 0.0 1.6 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 PSC70136.1 - 0.058 13.3 0.2 0.49 10.3 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 SDH_sah PF01972.16 PSC70136.1 - 0.086 11.8 0.1 0.12 11.3 0.1 1.1 1 0 0 1 1 1 0 Serine dehydrogenase proteinase MttA_Hcf106 PF02416.16 PSC70138.1 - 3.3e-18 64.7 0.2 6.4e-18 63.8 0.2 1.5 1 0 0 1 1 1 1 mttA/Hcf106 family RNase_T PF00929.24 PSC70139.1 - 5.7e-05 23.7 0.1 0.00027 21.5 0.1 1.9 1 1 0 1 1 1 1 Exonuclease EloA-BP1 PF15870.5 PSC70139.1 - 0.0013 19.0 0.0 0.0025 18.1 0.0 1.4 1 0 0 1 1 1 1 ElonginA binding-protein 1 Trypsin_2 PF13365.6 PSC70140.1 - 2.8e-07 31.5 0.6 5.4e-05 24.1 0.1 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain Trypsin PF00089.26 PSC70140.1 - 1.4e-05 25.0 0.6 5.4e-05 23.1 0.6 2.2 1 1 0 1 1 1 1 Trypsin Kazal_2 PF07648.15 PSC70140.1 - 0.005 16.9 3.1 0.011 15.9 3.1 1.5 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 PSC70140.1 - 0.26 11.3 1.5 0.51 10.4 1.5 1.4 1 0 0 1 1 1 0 Kazal-type serine protease inhibitor domain Rhodanese PF00581.20 PSC70141.1 - 2.9e-07 31.0 0.0 2.7e-06 27.9 0.0 2.4 2 1 0 2 2 2 1 Rhodanese-like domain Apolipoprotein PF01442.18 PSC70141.1 - 0.00039 20.3 0.0 0.00081 19.3 0.0 1.4 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain NIL PF09383.10 PSC70141.1 - 0.042 13.7 0.1 0.12 12.3 0.1 1.7 1 0 0 1 1 1 0 NIL domain AMP-binding PF00501.28 PSC70142.1 - 2.3e-66 224.2 0.0 3e-41 141.4 0.0 2.1 1 1 1 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 PSC70142.1 - 2.8e-05 25.0 0.1 6.8e-05 23.8 0.1 1.8 1 1 0 1 1 1 1 AMP-binding enzyme C-terminal domain TFIIA PF03153.13 PSC70143.1 - 2.6 7.9 9.0 3.2 7.7 9.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Kinesin PF00225.23 PSC70144.1 - 3.4e-116 387.8 0.0 4.8e-116 387.3 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PSC70144.1 - 2.9e-24 85.7 0.0 4.8e-21 75.2 0.0 2.3 2 0 0 2 2 2 2 Microtubule binding Peptidase_S8 PF00082.22 PSC70144.1 - 6.1e-22 78.2 0.1 6.1e-22 78.2 0.1 2.1 2 0 0 2 2 2 1 Subtilase family Bac_DnaA PF00308.18 PSC70144.1 - 0.012 15.5 0.0 0.028 14.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein Spc29 PF17082.5 PSC70144.1 - 0.12 12.2 2.1 0.26 11.1 2.1 1.6 1 0 0 1 1 1 0 Spindle Pole Component 29 SPX PF03105.19 PSC70144.1 - 7.3 6.4 14.3 1.2 9.0 0.5 2.3 2 0 0 2 2 2 0 SPX domain Aha1_N PF09229.11 PSC70145.1 - 1.8e-15 57.3 0.0 2.5e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal Tom5 PF10642.9 PSC70145.1 - 2.5 8.2 6.3 2 8.5 1.8 2.6 2 0 0 2 2 2 0 Mitochondrial import receptor subunit or translocase zf-MYND PF01753.18 PSC70146.1 - 2.5e-07 30.6 7.2 2.5e-07 30.6 7.2 1.8 2 0 0 2 2 2 1 MYND finger MFS_1 PF07690.16 PSC70149.1 - 0.31 9.9 27.0 0.098 11.6 14.4 2.0 1 1 1 2 2 2 0 Major Facilitator Superfamily MFS_1 PF07690.16 PSC70150.1 - 0.0046 15.9 53.6 0.0029 16.6 39.8 3.5 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_1 PF07690.16 PSC70151.1 - 0.31 9.9 39.5 0.083 11.8 25.7 2.7 1 1 1 2 2 2 0 Major Facilitator Superfamily Cupin_8 PF13621.6 PSC70152.1 - 3.5e-20 72.8 0.0 6.6e-20 71.9 0.0 1.4 1 1 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 PSC70152.1 - 1.8e-15 57.3 0.2 2e-14 54.0 0.2 2.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase MatE PF01554.18 PSC70154.1 - 1.6e-54 184.0 17.4 3e-29 101.7 1.1 2.1 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 PSC70154.1 - 0.0018 18.3 7.5 0.0018 18.3 7.5 4.0 3 2 0 3 3 3 2 Polysaccharide biosynthesis C-terminal domain Pentaxin PF00354.17 PSC70155.1 - 1e-43 149.3 0.3 2.5e-15 56.7 0.0 4.0 3 1 0 3 3 3 3 Pentaxin family Laminin_G_3 PF13385.6 PSC70155.1 - 2.9e-41 141.2 12.0 1.9e-15 57.3 0.1 5.9 3 2 0 3 3 3 3 Concanavalin A-like lectin/glucanases superfamily Laminin_G_2 PF02210.24 PSC70155.1 - 4.4e-09 37.0 0.1 0.15 12.6 0.0 3.3 3 0 0 3 3 3 3 Laminin G domain ATG16 PF08614.11 PSC70156.1 - 1.2e-05 25.6 16.4 1.2e-05 25.6 16.4 9.0 2 2 7 9 9 9 3 Autophagy protein 16 (ATG16) Fez1 PF06818.15 PSC70156.1 - 1.9e-05 25.2 94.6 0.0038 17.7 13.3 7.0 2 2 4 6 6 6 4 Fez1 Tropomyosin_1 PF12718.7 PSC70156.1 - 0.00017 21.7 36.5 0.00059 20.0 17.0 8.3 2 2 6 8 8 8 2 Tropomyosin like IFT57 PF10498.9 PSC70156.1 - 0.00056 19.0 36.5 0.025 13.5 1.4 6.4 3 2 0 6 6 6 5 Intra-flagellar transport protein 57 HMMR_N PF15905.5 PSC70156.1 - 0.00073 19.1 8.1 0.00073 19.1 8.1 5.9 1 1 4 6 6 5 1 Hyaluronan mediated motility receptor N-terminal Spc7 PF08317.11 PSC70156.1 - 0.0053 15.7 98.3 0.025 13.4 9.6 8.6 2 1 8 10 10 10 9 Spc7 kinetochore protein BORCS7 PF16088.5 PSC70156.1 - 0.034 14.4 0.6 0.034 14.4 0.6 4.1 4 1 0 4 4 4 0 BLOC-1-related complex sub-unit 7 HTH_35 PF13693.6 PSC70156.1 - 0.17 12.0 4.3 0.73 9.9 0.3 3.9 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding TMF_TATA_bd PF12325.8 PSC70156.1 - 0.27 11.5 81.3 1.3 9.3 0.5 9.8 4 3 3 9 9 9 0 TATA element modulatory factor 1 TATA binding ORF6C PF10552.9 PSC70156.1 - 0.51 10.4 6.1 0.51 10.4 0.2 3.8 4 0 0 4 4 4 0 ORF6C domain NPV_P10 PF05531.12 PSC70156.1 - 0.68 10.4 29.4 11 6.6 0.5 8.3 7 3 0 8 8 8 0 Nucleopolyhedrovirus P10 protein GAS PF13851.6 PSC70156.1 - 2.5 7.4 82.4 0.32 10.3 6.1 7.2 5 2 2 7 7 7 0 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 PSC70156.1 - 4.4 7.3 85.9 0.32 11.0 0.7 8.9 3 1 7 10 10 10 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Bcr-Abl_Oligo PF09036.10 PSC70156.1 - 5.9 7.0 8.0 5 7.2 0.1 4.7 4 1 1 5 5 5 0 Bcr-Abl oncoprotein oligomerisation domain DUF4201 PF13870.6 PSC70156.1 - 7.7 6.2 69.1 0.022 14.5 2.1 8.6 4 2 4 8 8 8 0 Domain of unknown function (DUF4201) F-box-like PF12937.7 PSC70157.1 - 0.00021 21.1 1.8 0.00021 21.1 1.8 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PSC70157.1 - 0.021 14.7 0.1 0.19 11.7 0.1 2.5 1 1 0 1 1 1 0 F-box domain AAA_22 PF13401.6 PSC70158.1 - 3.1e-08 34.0 0.0 5.3e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PSC70158.1 - 1.3e-07 32.2 1.4 0.0011 19.3 0.0 2.9 2 1 1 3 3 3 2 AAA ATPase domain AAA PF00004.29 PSC70158.1 - 2.3e-05 24.8 0.0 3.8e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 PSC70158.1 - 0.0025 18.3 0.0 0.0042 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PSC70158.1 - 0.0041 16.9 0.9 0.011 15.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 PSC70158.1 - 0.0043 16.7 0.0 0.41 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 PSC70158.1 - 0.0078 16.1 0.0 0.11 12.4 0.0 2.5 2 1 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 PSC70158.1 - 0.026 14.7 0.2 0.095 12.9 0.0 2.1 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 PSC70158.1 - 0.032 14.2 0.0 0.049 13.5 0.0 1.3 1 0 0 1 1 1 0 NTPase cobW PF02492.19 PSC70158.1 - 0.06 12.9 0.2 0.25 10.9 0.1 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_29 PF13555.6 PSC70158.1 - 0.074 12.8 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NB-ARC PF00931.22 PSC70158.1 - 0.088 12.0 0.0 0.13 11.4 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.6 PSC70158.1 - 0.12 12.6 0.1 0.32 11.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 PSC70158.1 - 0.15 11.7 0.1 0.24 11.1 0.1 1.2 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 PSC70158.1 - 0.16 11.8 0.0 0.49 10.3 0.0 1.6 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_5 PF07728.14 PSC70158.1 - 0.18 11.8 0.0 0.33 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 PSC70158.1 - 0.25 10.4 0.0 0.41 9.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DHQS PF01959.16 PSC70159.1 - 5.4e-101 338.0 0.0 4.3e-93 312.0 0.0 2.1 2 0 0 2 2 2 2 3-dehydroquinate synthase II Alfin PF12165.8 PSC70159.1 - 1.1e-57 193.2 0.0 1.7e-57 192.5 0.0 1.3 1 0 0 1 1 1 1 Alfin PrpF PF04303.13 PSC70159.1 - 0.0061 15.6 0.1 0.014 14.4 0.1 1.5 1 0 0 1 1 1 1 PrpF protein Pkinase PF00069.25 PSC70160.1 - 2.4e-49 168.1 0.0 3.1e-49 167.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC70160.1 - 1.4e-24 86.8 0.0 2e-24 86.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Hydrolase_like PF13242.6 PSC70160.1 - 1.1e-10 41.4 0.0 2.3e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 PSC70160.1 - 5.1e-07 30.0 0.0 7.6e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PSC70160.1 - 0.00018 21.9 0.0 0.00039 20.8 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Pkinase_fungal PF17667.1 PSC70160.1 - 0.0061 15.4 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RRN3 PF05327.11 PSC70161.1 - 1.1e-92 311.5 0.0 8.8e-91 305.1 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 PSC70161.1 - 0.0038 16.7 0.5 0.0063 16.0 0.5 1.3 1 0 0 1 1 1 1 SDA1 Sporozoite_P67 PF05642.11 PSC70161.1 - 1.7 6.6 19.5 1 7.3 16.3 1.9 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Nop14 PF04147.12 PSC70161.1 - 1.9 6.6 9.2 3 6.0 9.2 1.1 1 0 0 1 1 1 0 Nop14-like family SR-25 PF10500.9 PSC70161.1 - 7 6.2 16.7 12 5.4 16.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apt1 PF10351.9 PSC70161.1 - 8.3 5.1 7.5 13 4.5 7.5 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain LRR_4 PF12799.7 PSC70163.1 - 7.3e-10 39.0 0.0 0.083 13.4 0.0 5.4 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PSC70163.1 - 7.4e-07 28.7 18.3 0.031 14.3 0.4 8.8 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.33 PSC70163.1 - 7.6e-05 22.7 1.1 39 5.3 0.0 6.5 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.6 PSC70163.1 - 0.00015 21.4 0.2 11 5.9 0.0 5.3 6 1 0 6 6 6 2 Leucine rich repeat Pex14_N PF04695.13 PSC70163.1 - 1.3 9.6 9.7 2.2 8.9 9.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region 2OG-FeII_Oxy_3 PF13640.6 PSC70164.1 - 3.2e-08 34.4 0.0 6.6e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LPAM_1 PF08139.12 PSC70164.1 - 1.3 9.6 4.0 6.8 7.4 4.0 2.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site LRR_9 PF14580.6 PSC70165.1 - 5.9e-11 42.2 0.0 7.7e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 PSC70165.1 - 5.1e-09 36.3 10.0 0.00023 21.5 2.0 3.6 1 1 4 5 5 5 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC70165.1 - 3.6e-06 26.7 13.8 6.2e-05 22.7 9.8 2.7 2 0 0 2 2 2 2 Leucine rich repeat Cullin PF00888.22 PSC70166.1 - 2.1e-217 723.6 0.8 2.8e-217 723.2 0.8 1.1 1 0 0 1 1 1 1 Cullin family CLP_protease PF00574.23 PSC70166.1 - 8.1e-62 208.3 0.0 1.5e-61 207.5 0.0 1.4 1 0 0 1 1 1 1 Clp protease Cullin_Nedd8 PF10557.9 PSC70166.1 - 7.1e-27 93.2 0.2 1.8e-26 92.0 0.2 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain Sin_N PF04801.13 PSC70166.1 - 0.037 13.3 0.0 0.073 12.3 0.0 1.4 1 0 0 1 1 1 0 Sin-like protein conserved region TFIIF_beta PF02270.15 PSC70166.1 - 0.074 13.2 0.0 0.26 11.5 0.0 1.9 1 0 0 1 1 1 0 TFIIF, beta subunit HTH domain Asp_Arg_Hydrox PF05118.15 PSC70167.1 - 7.4e-35 120.1 0.1 1.2e-34 119.4 0.1 1.3 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase Acetyltransf_1 PF00583.25 PSC70167.1 - 2.7e-08 34.0 0.1 8.7e-08 32.4 0.1 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PSC70167.1 - 8.5e-07 29.3 0.0 1.7e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PSC70167.1 - 4.6e-05 23.4 0.0 0.0001 22.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC70167.1 - 0.00051 20.0 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Proteasom_PSMB PF10508.9 PSC70167.1 - 0.31 9.5 0.0 0.43 9.0 0.0 1.1 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit PRK PF00485.18 PSC70170.1 - 7.5e-77 257.5 0.0 3.3e-76 255.4 0.0 1.9 2 0 0 2 2 2 1 Phosphoribulokinase / Uridine kinase family DUF2722 PF10846.8 PSC70171.1 - 0.0039 16.2 0.4 0.0039 16.2 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Eapp_C PF10238.9 PSC70171.1 - 0.93 9.6 7.7 6.3 6.9 7.7 2.0 2 0 0 2 2 2 0 E2F-associated phosphoprotein TPR_MLP1_2 PF07926.12 PSC70173.1 - 0.0021 18.1 15.7 0.0021 18.1 15.7 8.4 4 3 4 8 8 8 1 TPR/MLP1/MLP2-like protein Exostosin PF03016.15 PSC70174.1 - 1.7e-37 129.2 0.0 4.2e-37 128.0 0.0 1.7 1 1 0 1 1 1 1 Exostosin family Metallophos PF00149.28 PSC70174.1 - 4.4e-09 37.1 0.0 1.4e-08 35.5 0.0 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Peptidase_C78 PF07910.13 PSC70175.1 - 1.4e-48 165.2 0.0 4e-33 114.7 0.0 2.4 2 1 0 2 2 2 2 Peptidase family C78 ZZ PF00569.17 PSC70175.1 - 9.8e-07 28.5 0.7 9.8e-07 28.5 0.7 1.8 2 0 0 2 2 1 1 Zinc finger, ZZ type zf-CCHC PF00098.23 PSC70175.1 - 0.00028 20.8 1.2 0.00028 20.8 1.2 1.9 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 PSC70175.1 - 0.0021 17.8 1.5 0.0061 16.4 1.5 1.8 1 0 0 1 1 1 1 Zinc knuckle eIF3g PF12353.8 PSC70175.1 - 0.012 16.0 0.0 0.024 15.0 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit G zf-CCHC_3 PF13917.6 PSC70175.1 - 0.012 15.6 0.1 0.03 14.3 0.1 1.7 1 0 0 1 1 1 0 Zinc knuckle zf_UBZ PF18439.1 PSC70175.1 - 0.029 14.0 0.3 0.029 14.0 0.3 2.4 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-ribbon_3 PF13248.6 PSC70175.1 - 0.085 12.3 5.3 1.9 8.0 0.2 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Anti-TRAP PF15777.5 PSC70175.1 - 0.27 11.2 0.0 0.27 11.2 0.0 3.1 3 0 0 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein TRAF6_Z2 PF18048.1 PSC70175.1 - 0.35 11.0 4.7 15 5.7 0.1 2.8 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 zf-CCHC_5 PF14787.6 PSC70175.1 - 5.7 6.7 8.5 0.18 11.5 1.5 2.1 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Peptidase_S8 PF00082.22 PSC70176.1 - 5.9e-40 137.4 6.6 5.9e-40 137.4 6.6 1.8 2 0 0 2 2 2 1 Subtilase family ABM PF03992.16 PSC70176.1 - 3.3e-07 30.3 0.0 8.5e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Ntox3 PF15536.6 PSC70176.1 - 0.057 13.4 0.1 0.14 12.2 0.1 1.6 1 0 0 1 1 1 0 Bacterial toxin 3 PAN_4 PF14295.6 PSC70176.1 - 0.075 13.0 2.8 1.2 9.1 0.6 2.3 2 0 0 2 2 2 0 PAN domain Prion_bPrPp PF11587.8 PSC70176.1 - 0.094 12.6 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Major prion protein bPrPp - N terminal N_Asn_amidohyd PF14736.6 PSC70177.1 - 2.2e-19 69.7 0.0 1e-18 67.5 0.0 2.0 1 1 0 1 1 1 1 Protein N-terminal asparagine amidohydrolase Spc7 PF08317.11 PSC70177.1 - 0.041 12.8 9.0 1.4 7.8 2.5 3.1 3 0 0 3 3 3 0 Spc7 kinetochore protein Bacillus_HBL PF05791.11 PSC70177.1 - 0.25 11.1 0.1 0.96 9.2 0.0 1.9 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) DUF4795 PF16043.5 PSC70177.1 - 0.3 10.6 1.6 2.1 7.9 0.0 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) Myosin_tail_1 PF01576.19 PSC70177.1 - 0.41 8.4 13.1 0.14 9.9 3.6 3.0 3 0 0 3 3 3 0 Myosin tail Med21 PF11221.8 PSC70177.1 - 1 9.6 6.1 0.72 10.1 1.2 3.1 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Baculo_PEP_C PF04513.12 PSC70177.1 - 1.3 9.1 2.6 19 5.3 0.2 3.5 3 1 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1090 PF06476.12 PSC70177.1 - 1.7 8.8 5.9 0.49 10.5 1.8 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF1090) Snapin_Pallidin PF14712.6 PSC70177.1 - 1.8 9.1 7.0 4.1 7.9 0.1 3.7 4 0 0 4 4 4 0 Snapin/Pallidin Bep_C_terminal PF17841.1 PSC70177.1 - 2.5 8.4 7.6 1 9.6 0.6 3.0 2 0 0 2 2 2 0 BID domain of Bartonella effector protein (Bep) DUF724 PF05266.14 PSC70177.1 - 3.5 7.4 5.4 0.76 9.6 0.7 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF724) ATG16 PF08614.11 PSC70177.1 - 4 7.6 28.7 0.37 11.0 7.8 4.5 4 0 0 4 4 4 0 Autophagy protein 16 (ATG16) DUF812 PF05667.11 PSC70177.1 - 5.1 5.9 5.5 2.5 6.9 1.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF812) ADIP PF11559.8 PSC70177.1 - 9 6.4 9.0 21 5.1 3.1 3.3 3 0 0 3 3 3 0 Afadin- and alpha -actinin-Binding AAA_13 PF13166.6 PSC70177.1 - 9.4 4.7 5.5 1.7 7.2 1.8 1.5 2 0 0 2 2 2 0 AAA domain TMF_TATA_bd PF12325.8 PSC70177.1 - 9.4 6.5 14.9 2 8.6 2.3 4.1 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding NYD-SP28 PF14772.6 PSC70178.1 - 1.8e-11 44.0 0.0 1.8e-11 44.0 0.0 4.1 3 1 1 4 4 4 1 Sperm tail NYD-SP28_assoc PF14775.6 PSC70178.1 - 2.6e-05 24.2 0.1 2.6e-05 24.2 0.1 3.5 4 0 0 4 4 4 1 Sperm tail C-terminal domain DUF5339 PF17274.2 PSC70178.1 - 0.56 11.1 4.1 38 5.2 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5339) Ribosomal_S8e PF01201.22 PSC70180.1 - 1e-44 152.1 4.6 1.5e-44 151.5 4.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S8e Red1 PF07964.11 PSC70180.1 - 2.3 6.4 8.8 2.7 6.1 8.8 1.0 1 0 0 1 1 1 0 Rec10 / Red1 SNF2_N PF00176.23 PSC70181.1 - 9.2e-63 212.1 0.8 1.4e-61 208.1 0.0 2.8 1 1 1 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC70181.1 - 7.5e-17 61.7 0.0 2.2e-16 60.2 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Prok-RING_4 PF14447.6 PSC70181.1 - 8e-06 25.6 6.1 1.6e-05 24.7 6.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 PSC70181.1 - 1.5e-05 24.8 4.5 3e-05 23.8 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PSC70181.1 - 2e-05 24.3 7.2 7.4e-05 22.5 7.2 2.0 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC70181.1 - 6.2e-05 22.8 4.8 0.00011 22.0 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC70181.1 - 0.00011 22.1 5.7 0.0002 21.3 5.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 PSC70181.1 - 0.00026 21.2 5.3 0.00048 20.4 5.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 PSC70181.1 - 0.0016 18.4 3.4 0.004 17.2 3.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PSC70181.1 - 0.022 14.9 5.5 0.045 13.9 5.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 PSC70181.1 - 0.057 13.3 0.4 0.17 11.7 0.4 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 PSC70181.1 - 0.27 11.6 4.1 0.82 10.0 4.1 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain bMG3 PF11974.8 PSC70181.1 - 0.38 10.8 3.5 6.1 6.9 2.2 3.4 2 1 0 2 2 2 0 Bacterial alpha-2-macroglobulin MG3 domain rve PF00665.26 PSC70182.1 - 5.3e-19 68.6 0.0 1.1e-18 67.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC70182.1 - 0.0048 16.7 0.0 0.013 15.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Chloroa_b-bind PF00504.21 PSC70183.1 - 8.2e-12 45.9 5.6 3.6e-06 27.6 0.2 2.2 1 1 1 2 2 2 2 Chlorophyll A-B binding protein fn3 PF00041.21 PSC70184.1 - 0.1 13.0 8.8 4.5 7.7 0.1 5.7 7 0 0 7 7 7 0 Fibronectin type III domain F1F0-ATPsyn_F PF10791.9 PSC70185.1 - 0.11 13.0 0.1 0.16 12.5 0.1 1.4 1 1 0 1 1 1 0 Mitochondrial F1-F0 ATP synthase subunit F of fungi Peptidase_S10 PF00450.22 PSC70186.1 - 8.5e-110 368.0 0.0 1.1e-109 367.6 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase RuvX PF03652.15 PSC70186.1 - 4.1e-24 85.5 0.1 6.6e-24 84.8 0.1 1.3 1 0 0 1 1 1 1 Holliday junction resolvase DUF726 PF05277.12 PSC70187.1 - 2.5e-70 237.1 11.6 2.9e-51 174.4 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF726) UCH PF00443.29 PSC70187.1 - 1.3e-69 234.5 0.0 4.2e-69 232.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PDDEXK_6 PF04720.12 PSC70187.1 - 1.9e-19 70.5 0.0 1.9e-19 70.5 0.0 2.8 3 0 0 3 3 2 1 PDDEXK-like family of unknown function DUSP PF06337.12 PSC70187.1 - 1.9e-14 54.0 0.0 1.9e-14 54.0 0.0 2.3 2 0 0 2 2 1 1 DUSP domain UCH_1 PF13423.6 PSC70187.1 - 1.5e-09 37.9 24.8 0.00067 19.3 17.5 4.2 3 2 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase TFIIA PF03153.13 PSC70187.1 - 3.9e-06 27.1 39.0 3.9e-06 27.1 39.0 3.1 3 0 0 3 3 3 2 Transcription factor IIA, alpha/beta subunit DUF4746 PF15928.5 PSC70187.1 - 0.53 9.7 10.9 1.1 8.6 10.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DDHD PF02862.17 PSC70187.1 - 1.3 9.2 18.5 0.2 11.8 10.0 2.5 2 0 0 2 2 2 0 DDHD domain SpoIIP PF07454.11 PSC70187.1 - 2.6 7.4 22.8 0.22 10.9 16.4 2.0 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) EPL1 PF10513.9 PSC70187.1 - 4.8 7.5 24.6 5.6 7.3 17.6 2.6 2 0 0 2 2 2 0 Enhancer of polycomb-like Otopetrin PF03189.13 PSC70187.1 - 4.9 5.9 5.1 7.6 5.2 5.1 1.2 1 0 0 1 1 1 0 Otopetrin AAA_23 PF13476.6 PSC70187.1 - 9.4 6.7 18.3 21 5.5 18.3 1.5 1 0 0 1 1 1 0 AAA domain Prefoldin_2 PF01920.20 PSC70188.1 - 1.1e-14 54.3 0.2 1.3e-14 54.0 0.2 1.1 1 0 0 1 1 1 1 Prefoldin subunit TMF_TATA_bd PF12325.8 PSC70188.1 - 0.00069 19.8 0.3 0.97 9.7 0.0 2.0 2 0 0 2 2 2 2 TATA element modulatory factor 1 TATA binding APG6_N PF17675.1 PSC70188.1 - 0.0017 18.9 6.0 0.0088 16.6 1.2 2.0 2 0 0 2 2 2 1 Apg6 coiled-coil region Prefoldin PF02996.17 PSC70188.1 - 0.014 15.3 0.2 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 Prefoldin subunit DUF4407 PF14362.6 PSC70188.1 - 0.084 12.2 3.4 0.087 12.2 3.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5595 PF18077.1 PSC70188.1 - 0.13 12.3 0.7 11 6.2 0.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) AAA_13 PF13166.6 PSC70188.1 - 0.19 10.3 2.2 4.8 5.7 0.7 2.0 1 1 1 2 2 2 0 AAA domain Spc7 PF08317.11 PSC70188.1 - 0.32 9.9 4.3 3.4 6.5 1.3 2.0 2 0 0 2 2 2 0 Spc7 kinetochore protein DivIC PF04977.15 PSC70188.1 - 2.4 8.0 6.1 4 7.3 3.6 2.0 2 0 0 2 2 2 0 Septum formation initiator TPR_2 PF07719.17 PSC70189.1 - 1e-05 25.2 11.3 0.0011 19.0 0.5 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 PSC70189.1 - 1.8e-05 24.3 6.6 0.0054 16.5 0.3 3.3 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 PSC70189.1 - 0.00041 20.3 1.5 0.0055 16.8 0.0 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PSC70189.1 - 0.0012 19.5 1.0 0.0012 19.5 1.0 4.3 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_15 PF13429.6 PSC70189.1 - 0.0066 15.7 3.0 0.013 14.8 3.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 PSC70189.1 - 0.013 15.1 6.4 0.39 10.4 0.1 3.4 1 1 2 3 3 3 0 TPR repeat TPR_16 PF13432.6 PSC70189.1 - 0.059 14.0 12.8 0.093 13.4 3.3 3.7 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 PSC70189.1 - 0.26 11.4 1.9 0.56 10.4 0.2 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 PSC70189.1 - 3.9 7.7 10.4 2.7 8.2 0.5 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat RabGAP-TBC PF00566.18 PSC70190.1 - 7.9e-25 87.8 0.0 7.9e-25 87.8 0.0 3.6 4 0 0 4 4 4 2 Rab-GTPase-TBC domain RRM_1 PF00076.22 PSC70190.1 - 5.3e-08 32.6 0.0 1.1e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Adaptin_binding PF10199.9 PSC70190.1 - 3 8.5 18.2 36 5.0 0.2 3.6 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 rve PF00665.26 PSC70191.1 - 7.5e-16 58.4 0.0 1.7e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DFRP_C PF16543.5 PSC70191.1 - 3.9e-15 56.1 7.0 3.9e-15 56.1 7.0 2.9 4 0 0 4 4 4 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 PSC70191.1 - 8.1e-08 32.9 4.5 0.00041 21.0 0.1 3.6 3 0 0 3 3 3 2 Torus domain zf-CCCH PF00642.24 PSC70191.1 - 0.0025 17.7 10.9 0.0035 17.2 3.3 2.8 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PSC70191.1 - 0.005 16.6 4.1 0.005 16.6 4.1 2.9 2 1 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_3 PF15663.5 PSC70191.1 - 0.21 11.8 1.1 3.2 8.0 0.1 2.4 2 0 0 2 2 2 0 Zinc-finger containing family JHY PF15261.6 PSC70191.1 - 0.67 10.7 7.1 0.044 14.5 1.3 2.0 2 0 0 2 2 2 0 Jhy protein zf_CCCH_4 PF18345.1 PSC70191.1 - 3.1 8.0 24.2 0.78 9.9 9.0 3.0 3 0 0 3 3 3 0 Zinc finger domain AP2 PF00847.20 PSC70192.1 - 1.2e-05 25.5 0.2 3.4e-05 24.0 0.2 1.8 1 0 0 1 1 1 1 AP2 domain TraB PF01963.17 PSC70192.1 - 0.0019 18.1 0.2 0.016 15.1 0.2 2.0 1 1 0 1 1 1 1 TraB family Glyco_trans_4_4 PF13579.6 PSC70193.1 - 2e-07 31.6 10.4 2e-07 31.6 10.4 2.9 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_transf_4 PF13439.6 PSC70193.1 - 0.00025 21.1 1.5 0.0008 19.5 1.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 PSC70193.1 - 0.021 14.4 0.0 0.053 13.1 0.0 1.7 1 0 0 1 1 1 0 Glycosyl transferases group 1 NADHdh_A3 PF14987.6 PSC70194.1 - 0.00057 20.1 0.1 0.00058 20.1 0.1 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 alpha subcomplex subunit 3 NADHdh_A3 PF14987.6 PSC70195.1 - 0.0036 17.6 0.0 0.0048 17.2 0.0 1.2 1 0 0 1 1 1 1 NADH dehydrogenase 1 alpha subcomplex subunit 3 zf-CCCH PF00642.24 PSC70196.1 - 1.5e-09 37.6 14.9 0.0011 18.8 1.8 3.4 3 0 0 3 3 3 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PSC70196.1 - 6.5e-08 32.4 19.5 2.6e-05 24.1 1.3 3.4 4 0 0 4 4 4 2 Zinc finger domain Torus PF16131.5 PSC70196.1 - 2.3e-06 28.3 10.4 2.9e-05 24.7 0.1 2.8 1 1 2 3 3 3 2 Torus domain zf-CCCH_4 PF18044.1 PSC70196.1 - 0.0037 17.0 0.4 0.0037 17.0 0.4 3.0 4 0 0 4 4 4 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 PSC70196.1 - 0.009 16.2 9.2 0.014 15.6 2.1 2.3 1 1 1 2 2 2 2 Zinc-finger containing family zf-C3H1 PF10650.9 PSC70196.1 - 0.18 11.6 6.2 3.1 7.6 0.3 3.1 3 0 0 3 3 3 0 Putative zinc-finger domain zf-CCCH_2 PF14608.6 PSC70196.1 - 0.78 10.3 17.6 4.6 7.9 2.8 3.4 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger DUF3523 PF12037.8 PSC70197.1 - 2.5e-82 276.3 29.1 3.7e-82 275.7 28.8 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF3523) AAA PF00004.29 PSC70197.1 - 2.7e-24 86.1 0.0 8e-24 84.6 0.0 1.9 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PSC70197.1 - 0.00011 22.0 0.0 0.00025 20.8 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 PSC70197.1 - 0.00029 20.3 0.1 0.0007 19.0 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 PSC70197.1 - 0.002 18.5 0.0 0.002 18.5 0.0 3.9 2 2 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 PSC70197.1 - 0.003 17.8 8.3 0.013 15.8 0.0 3.4 2 2 1 3 3 2 1 AAA domain AAA_33 PF13671.6 PSC70197.1 - 0.0055 16.9 0.0 0.0055 16.9 0.0 3.1 2 2 1 3 3 2 1 AAA domain AAA_5 PF07728.14 PSC70197.1 - 0.0058 16.6 0.1 0.04 13.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.6 PSC70197.1 - 0.021 15.2 0.2 0.021 15.2 0.2 3.3 2 1 1 3 3 3 0 AAA domain AAA_18 PF13238.6 PSC70197.1 - 0.026 15.1 0.0 0.026 15.1 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_7 PF12775.7 PSC70197.1 - 0.036 13.6 0.0 0.08 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 PSC70197.1 - 0.039 13.7 3.0 0.11 12.2 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 PSC70197.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 PSC70197.1 - 0.074 13.5 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.6 PSC70197.1 - 0.19 11.9 0.0 0.19 11.9 0.0 3.8 3 1 0 3 3 2 0 AAA domain CDK5_activator PF03261.15 PSC70197.1 - 0.67 9.4 6.6 0.97 8.9 6.6 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein AAA_11 PF13086.6 PSC70197.1 - 1.4 8.6 0.0 1.4 8.6 0.0 3.2 2 1 1 3 3 3 0 AAA domain FGGY_N PF00370.21 PSC70198.1 - 2.6e-56 190.9 0.0 2.5e-41 141.8 0.0 2.2 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 PSC70198.1 - 2.5e-25 89.4 0.0 4.4e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 PSC70198.1 - 0.02 14.4 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family Slu7 PF11708.8 PSC70199.1 - 2e-82 277.0 12.6 2e-82 277.0 12.6 2.4 2 1 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 PSC70199.1 - 0.19 11.5 0.5 1 9.2 0.7 2.0 2 0 0 2 2 2 0 Zinc knuckle DUF3128 PF11326.8 PSC70199.1 - 6 7.3 8.7 1.2 9.6 0.4 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3128) PK PF00224.21 PSC70200.1 - 3.6e-153 509.5 0.5 4.8e-153 509.1 0.5 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 PSC70200.1 - 8.5e-22 77.6 1.9 1.2e-21 77.1 0.5 2.0 2 1 1 3 3 3 1 Pyruvate kinase, alpha/beta domain Zip PF02535.22 PSC70200.1 - 4e-16 59.2 12.1 1.6e-14 53.9 9.0 2.9 1 1 1 2 2 2 2 ZIP Zinc transporter UBA PF00627.31 PSC70201.1 - 2.7e-12 46.3 0.2 5.7e-12 45.3 0.2 1.6 1 0 0 1 1 1 1 UBA/TS-N domain Rhomboid PF01694.22 PSC70201.1 - 0.0017 18.4 4.0 0.0031 17.5 4.0 1.4 1 0 0 1 1 1 1 Rhomboid family UBA_3 PF09288.10 PSC70201.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain Ribosomal_S2 PF00318.20 PSC70202.1 - 1.2e-27 96.6 0.3 2.9e-15 56.1 0.1 2.0 1 1 1 2 2 2 2 Ribosomal protein S2 40S_SA_C PF16122.5 PSC70202.1 - 5.1 8.5 13.7 12 7.3 13.7 1.7 1 1 0 1 1 1 0 40S ribosomal protein SA C-terminus Cwf_Cwc_15 PF04889.12 PSC70203.1 - 6.1e-68 229.2 18.0 9.6e-68 228.6 18.0 1.3 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 PSC70203.1 - 4.5 6.5 11.0 6 6.1 11.0 1.2 1 0 0 1 1 1 0 NOA36 protein Myb_DNA-binding PF00249.31 PSC70204.1 - 0.015 15.4 0.0 0.027 14.7 0.0 1.4 1 0 0 1 1 1 0 Myb-like DNA-binding domain p450 PF00067.22 PSC70205.1 - 6.1e-64 216.5 0.0 8.3e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 Cytochrome P450 Elongin_A PF06881.11 PSC70205.1 - 6.5e-07 29.8 0.0 6.5e-07 29.8 0.0 3.3 4 0 0 4 4 4 1 RNA polymerase II transcription factor SIII (Elongin) subunit A DctQ PF04290.12 PSC70205.1 - 0.33 10.9 2.3 0.72 9.8 2.3 1.5 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component Ank_4 PF13637.6 PSC70206.1 - 1.3e-15 57.5 0.3 1.8e-06 28.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PSC70206.1 - 1.6e-14 54.2 5.9 1.2e-11 45.0 1.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC70206.1 - 1.9e-10 40.8 0.9 0.00035 20.8 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 PSC70206.1 - 3.5e-10 39.9 4.1 2.8e-05 24.4 0.7 3.2 3 0 0 3 3 3 2 Ankyrin repeat zf-C3HC4_3 PF13920.6 PSC70206.1 - 4.3e-10 39.3 4.5 7.1e-10 38.6 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank_3 PF13606.6 PSC70206.1 - 5.2e-09 35.6 1.8 0.02 15.4 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat zf-RING_2 PF13639.6 PSC70206.1 - 0.071 13.5 5.4 0.13 12.6 5.4 1.5 1 0 0 1 1 1 0 Ring finger domain TetR_C_11 PF16859.5 PSC70206.1 - 0.31 11.3 3.5 4.2 7.7 0.0 3.3 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Prok-RING_4 PF14447.6 PSC70206.1 - 0.61 10.0 6.0 1.4 8.9 6.0 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Usp PF00582.26 PSC70208.1 - 6.1e-22 78.6 1.7 2.5e-21 76.7 1.7 1.8 1 1 0 1 1 1 1 Universal stress protein family tRNA_Me_trans PF03054.16 PSC70209.1 - 3e-94 315.7 0.0 4e-94 315.3 0.0 1.1 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 PSC70209.1 - 5.1e-06 25.8 0.0 1.4e-05 24.4 0.0 1.7 2 0 0 2 2 2 1 NAD synthase ThiI PF02568.14 PSC70209.1 - 0.00075 19.1 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) Pkr1 PF08636.10 PSC70209.1 - 0.002 18.2 2.7 0.0065 16.6 2.4 1.9 2 0 0 2 2 2 1 ER protein Pkr1 Asn_synthase PF00733.21 PSC70209.1 - 0.1 12.3 0.0 0.14 11.8 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase SdiA-regulated PF06977.11 PSC70209.1 - 0.19 10.9 0.0 14 4.8 0.0 2.6 3 0 0 3 3 3 0 SdiA-regulated PSRP-3_Ycf65 PF04839.13 PSC70211.1 - 3.3e-25 88.0 2.2 5.1e-25 87.4 2.2 1.3 1 0 0 1 1 1 1 Plastid and cyanobacterial ribosomal protein (PSRP-3 / Ycf65) CAS_CSE1 PF03378.15 PSC70211.1 - 0.12 10.9 0.1 0.14 10.6 0.1 1.1 1 0 0 1 1 1 0 CAS/CSE protein, C-terminus DUF1744 PF08490.12 PSC70212.1 - 6.6e-101 337.8 0.0 5.6e-100 334.7 0.0 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 PSC70212.1 - 3.1e-74 250.1 0.1 4.5e-74 249.6 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain TauD PF02668.16 PSC70212.1 - 9e-27 94.5 0.3 2.1e-26 93.3 0.3 1.6 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family DNA_pol_B PF00136.21 PSC70212.1 - 5.1e-17 61.7 0.0 2.3e-14 53.0 0.0 3.6 4 1 0 4 4 4 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 PSC70212.1 - 7.3e-06 25.8 0.1 1.7e-05 24.6 0.1 1.5 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 PSC70212.1 - 2.6e-05 24.3 0.0 8.5e-05 22.6 0.0 1.9 1 1 0 1 1 1 1 RNase_H superfamily Forkhead PF00250.18 PSC70213.1 - 0.00012 22.3 0.0 0.00025 21.2 0.0 1.5 1 0 0 1 1 1 1 Forkhead domain Ctr PF04145.15 PSC70213.1 - 0.19 12.3 3.2 0.18 12.4 0.4 2.2 2 0 0 2 2 2 0 Ctr copper transporter family BAF1_ABF1 PF04684.13 PSC70213.1 - 0.33 10.0 4.3 0.64 9.0 4.3 1.6 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4746 PF15928.5 PSC70213.1 - 4.3 6.7 9.0 1.2 8.6 0.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) TOM20_plant PF06552.12 PSC70214.1 - 2.6e-08 33.9 0.2 0.38 10.5 0.0 3.3 2 1 1 3 3 3 3 Plant specific mitochondrial import receptor subunit TOM20 TPR_11 PF13414.6 PSC70214.1 - 0.00096 18.8 4.2 0.96 9.2 0.0 3.7 3 1 1 4 4 4 2 TPR repeat DUF5076 PF16826.5 PSC70214.1 - 0.051 13.5 1.6 0.84 9.6 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF5076) Med3 PF11593.8 PSC70214.1 - 3.2 6.8 4.8 5 6.2 4.8 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NADH_B2 PF14813.6 PSC70215.1 - 4.2e-07 29.6 4.0 6.4e-07 29.1 4.0 1.3 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 Asn_synthase PF00733.21 PSC70217.1 - 7e-17 62.1 2.4 2.6e-07 30.6 1.2 3.4 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 PSC70217.1 - 6.7e-05 22.8 0.0 0.00016 21.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 PSC70217.1 - 0.011 15.9 0.0 0.011 15.9 0.0 2.9 4 0 0 4 4 4 0 Glutamine amidotransferase domain NAD_synthase PF02540.17 PSC70217.1 - 0.19 10.8 0.0 0.3 10.2 0.0 1.2 1 0 0 1 1 1 0 NAD synthase QueC PF06508.13 PSC70217.1 - 0.19 11.2 0.0 0.33 10.4 0.0 1.3 1 0 0 1 1 1 0 Queuosine biosynthesis protein QueC F-box PF00646.33 PSC70218.1 - 0.22 11.4 0.4 4 7.4 0.0 2.4 2 0 0 2 2 2 0 F-box domain DAGAT PF03982.13 PSC70219.1 - 4.5e-49 167.0 0.0 5.4e-49 166.7 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Acyltransferase PF01553.21 PSC70219.1 - 4.5e-05 23.1 0.0 9.5e-05 22.0 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase Furin-like_2 PF15913.5 PSC70220.1 - 0.016 15.3 18.8 0.016 15.3 18.8 6.1 1 1 1 5 5 5 0 Furin-like repeat, cysteine-rich VSP PF03302.13 PSC70220.1 - 0.038 12.8 90.0 0.13 11.1 22.6 5.0 1 1 4 5 5 5 0 Giardia variant-specific surface protein TPR_12 PF13424.6 PSC70221.1 - 8.8e-05 22.7 8.3 8.8e-05 22.7 8.3 4.1 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 PSC70221.1 - 0.013 15.1 2.1 0.41 10.4 0.6 2.8 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.28 PSC70221.1 - 0.72 9.8 5.3 6.9 6.7 0.4 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 PSC70221.1 - 6.2 7.2 20.0 1.7 9.0 2.4 5.0 3 2 0 4 4 4 0 Tetratricopeptide repeat ANAPC4_WD40 PF12894.7 PSC70222.1 - 6.4e-11 42.4 0.0 4 7.8 0.0 6.9 2 2 4 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PSC70222.1 - 7.1e-09 36.2 14.3 4.5 8.3 0.1 8.5 7 1 2 9 9 9 4 WD domain, G-beta repeat PD40 PF07676.12 PSC70222.1 - 3.4e-07 30.0 7.8 17 5.5 0.0 8.0 8 0 0 8 8 8 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 PSC70222.1 - 2.1e-05 24.5 0.0 3.5 7.4 0.0 4.2 2 2 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 PSC70222.1 - 0.00027 19.1 0.1 1.3 7.0 0.0 4.2 2 2 0 3 3 3 1 IKI3 family TruB_C PF09142.11 PSC70222.1 - 0.00092 18.9 2.3 30 4.5 0.1 5.6 5 1 1 6 6 6 0 tRNA Pseudouridine synthase II, C terminal DPPIV_N PF00930.21 PSC70222.1 - 0.0013 17.6 0.7 8.2 5.1 0.1 5.1 4 2 2 6 6 6 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region SGL PF08450.12 PSC70222.1 - 0.0038 16.9 0.0 0.46 10.0 0.0 3.1 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Nbas_N PF15492.6 PSC70222.1 - 0.013 14.9 1.8 2.5 7.3 0.0 3.9 2 1 3 5 5 5 0 Neuroblastoma-amplified sequence, N terminal Shadoo PF14999.6 PSC70222.1 - 0.19 11.8 4.5 0.44 10.7 4.5 1.5 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective Far-17a_AIG1 PF04750.14 PSC70223.1 - 0.044 13.1 8.2 0.078 12.3 8.2 1.3 1 0 0 1 1 1 0 FAR-17a/AIG1-like protein Herpes_UL25 PF01499.16 PSC70223.1 - 0.65 8.5 1.9 4.7 5.6 0.9 2.0 2 0 0 2 2 2 0 Herpesvirus UL25 family BatD PF13584.6 PSC70223.1 - 6 5.6 5.5 8.7 5.0 0.9 2.1 2 0 0 2 2 2 0 Oxygen tolerance GTP_EFTU PF00009.27 PSC70224.1 - 1.7e-35 122.3 0.4 4.9e-34 117.6 0.4 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 PSC70224.1 - 3.3e-27 94.7 0.0 7.8e-27 93.5 0.0 1.7 1 0 0 1 1 1 1 Translation-initiation factor 2 IF2_N PF04760.15 PSC70224.1 - 5.6e-12 45.3 0.0 2.9e-11 43.0 0.0 2.2 2 0 0 2 2 2 1 Translation initiation factor IF-2, N-terminal region MMR_HSR1 PF01926.23 PSC70224.1 - 4.6e-07 29.9 0.1 8.4e-07 29.1 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 PSC70224.1 - 1.7e-05 24.5 0.0 3e-05 23.7 0.0 1.3 1 0 0 1 1 1 1 Ras family FeoB_N PF02421.18 PSC70224.1 - 0.0003 20.3 0.0 0.00082 18.9 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PSC70224.1 - 0.00049 20.1 0.0 0.15 12.0 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU_D4 PF14578.6 PSC70224.1 - 0.00053 19.8 2.7 0.056 13.3 1.1 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MeaB PF03308.16 PSC70224.1 - 0.0016 17.5 0.1 0.0035 16.4 0.1 1.6 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Roc PF08477.13 PSC70224.1 - 0.0043 17.3 0.0 0.0076 16.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1_Xtn PF16897.5 PSC70224.1 - 0.0052 16.8 0.0 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 PSC70224.1 - 0.0064 16.0 0.0 0.03 13.8 0.0 2.1 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.25 PSC70224.1 - 0.012 16.0 5.8 2.5 8.5 0.0 3.5 3 1 0 3 3 3 0 Elongation factor Tu domain 2 Arf PF00025.21 PSC70224.1 - 0.042 13.3 0.0 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor family HSF_DNA-bind PF00447.17 PSC70225.1 - 6.3e-28 97.2 0.1 1e-27 96.5 0.1 1.4 1 0 0 1 1 1 1 HSF-type DNA-binding PsbP PF01789.16 PSC70225.1 - 1.4e-13 51.2 0.0 1.4e-12 48.0 0.0 2.1 2 0 0 2 2 2 1 PsbP APG6_N PF17675.1 PSC70225.1 - 0.034 14.7 2.6 0.063 13.8 2.6 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region TMF_DNA_bd PF12329.8 PSC70225.1 - 0.19 11.7 4.2 0.3 11.1 4.2 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Taxilin PF09728.9 PSC70225.1 - 0.29 10.3 6.1 0.46 9.6 6.1 1.2 1 0 0 1 1 1 0 Myosin-like coiled-coil protein DUF4763 PF15960.5 PSC70225.1 - 0.41 9.9 6.6 0.63 9.3 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) GSHPx PF00255.19 PSC70226.1 - 6.8e-39 131.8 0.0 8.8e-39 131.4 0.0 1.1 1 0 0 1 1 1 1 Glutathione peroxidase AhpC-TSA PF00578.21 PSC70226.1 - 7.2e-07 29.2 0.0 2.4e-06 27.5 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PSC70226.1 - 0.00026 20.7 0.0 0.0015 18.2 0.0 1.9 1 1 0 1 1 1 1 Redoxin DnaJ PF00226.31 PSC70227.1 - 2.8e-18 65.8 0.0 6.7e-18 64.6 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain ADH_zinc_N PF00107.26 PSC70227.1 - 1.2e-11 44.7 0.0 2.1e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PSC70227.1 - 8.4e-07 28.9 0.0 2.4e-06 27.4 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 PSC70227.1 - 7.2e-06 27.1 0.1 2e-05 25.7 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Dak2 PF02734.17 PSC70227.1 - 0.11 12.4 0.1 9.1 6.1 0.1 2.5 2 0 0 2 2 2 0 DAK2 domain Transferrin PF00405.17 PSC70228.1 - 1.6e-101 339.8 1.9 5.1e-50 170.5 1.0 2.1 2 0 0 2 2 2 2 Transferrin Phosphonate-bd PF12974.7 PSC70228.1 - 6.3e-20 71.8 0.2 4.7e-09 36.2 0.0 4.0 3 1 0 3 3 3 3 ABC transporter, phosphonate, periplasmic substrate-binding protein Usp PF00582.26 PSC70228.1 - 0.15 12.6 0.0 4.2 7.9 0.0 2.4 2 0 0 2 2 2 0 Universal stress protein family DUF4079 PF13301.6 PSC70229.1 - 1.4e-48 164.7 0.6 2.5e-48 163.8 0.6 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) MARVEL PF01284.23 PSC70229.1 - 0.0044 17.1 2.6 0.46 10.5 0.2 2.2 2 0 0 2 2 2 2 Membrane-associating domain DUF5389 PF17364.2 PSC70229.1 - 0.24 11.5 1.3 0.5 10.4 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5389) UPF0016 PF01169.19 PSC70230.1 - 3.9e-37 126.4 29.6 1.5e-21 76.5 7.0 2.9 3 0 0 3 3 3 2 Uncharacterized protein family UPF0016 LysE PF01810.18 PSC70230.1 - 0.01 15.3 8.5 0.022 14.2 5.8 2.6 1 1 2 3 3 3 0 LysE type translocator DUF4702 PF15774.5 PSC70230.1 - 0.091 11.7 0.6 0.12 11.3 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4702) E1-E2_ATPase PF00122.20 PSC70230.1 - 0.25 10.9 2.3 0.15 11.5 0.2 1.7 2 0 0 2 2 2 0 E1-E2 ATPase Na_H_Exchanger PF00999.21 PSC70232.1 - 8e-61 205.9 37.6 8e-61 205.9 37.6 1.5 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family zf-MYND PF01753.18 PSC70232.1 - 7.6e-06 25.9 12.3 7.6e-06 25.9 12.3 1.8 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 PSC70232.1 - 4.3 7.5 5.4 12 6.1 5.4 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Peptidase_S9 PF00326.21 PSC70233.1 - 5.5e-38 130.6 0.0 1e-37 129.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 PSC70233.1 - 6.7e-10 38.6 0.1 5.5e-07 29.1 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PSC70233.1 - 1.7e-09 37.7 0.5 9.9e-08 31.9 0.9 2.3 1 1 1 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 PSC70233.1 - 3.2e-07 29.6 0.0 4.6e-07 29.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family DLH PF01738.18 PSC70233.1 - 2.1e-05 24.2 0.0 0.00097 18.8 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family PD40 PF07676.12 PSC70233.1 - 0.00034 20.5 0.0 0.0013 18.6 0.0 2.0 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat Abhydrolase_3 PF07859.13 PSC70233.1 - 0.003 17.4 0.0 0.0072 16.2 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 PSC70233.1 - 0.035 13.7 0.0 0.093 12.4 0.0 1.8 1 0 0 1 1 1 0 Putative esterase Dodecin PF07311.12 PSC70233.1 - 0.39 11.0 1.4 4.8 7.5 0.1 2.4 2 0 0 2 2 2 0 Dodecin E1_dh PF00676.20 PSC70234.1 - 2.3e-62 210.6 0.3 3.6e-34 118.1 0.0 3.2 2 1 1 3 3 3 3 Dehydrogenase E1 component Rdx PF10262.9 PSC70235.1 - 0.0022 18.2 0.0 0.0029 17.8 0.0 1.3 1 0 0 1 1 1 1 Rdx family Aldo_ket_red PF00248.21 PSC70236.1 - 9.6e-50 169.4 0.0 1.5e-49 168.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FSH1 PF03959.13 PSC70236.1 - 4.3e-37 127.8 0.0 2e-36 125.6 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase (FSH1) Aldo_ket_red PF00248.21 PSC70237.1 - 9.2e-50 169.5 0.0 1.4e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family FSH1 PF03959.13 PSC70237.1 - 4e-37 128.0 0.0 2e-36 125.7 0.0 1.9 2 0 0 2 2 2 1 Serine hydrolase (FSH1) rve PF00665.26 PSC70238.1 - 9.4e-19 67.8 0.0 2.7e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC70238.1 - 0.01 15.6 0.0 0.027 14.2 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain OTU PF02338.19 PSC70239.1 - 4.7e-07 30.3 0.2 1.2e-06 29.1 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease OAD_gamma PF04277.13 PSC70239.1 - 0.008 16.8 3.1 0.91 10.2 0.4 2.9 3 0 0 3 3 3 2 Oxaloacetate decarboxylase, gamma chain Itfg2 PF15907.5 PSC70239.1 - 0.038 13.0 1.9 0.077 12.0 1.9 1.4 1 0 0 1 1 1 0 Integrin-alpha FG-GAP repeat-containing protein 2 Presenilin PF01080.17 PSC70239.1 - 2.3 6.9 4.2 3.5 6.3 4.2 1.2 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 PSC70239.1 - 3.8 8.5 8.9 7.6 7.6 8.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Fer2 PF00111.27 PSC70240.1 - 1.7e-10 40.7 3.7 2.4e-10 40.2 3.7 1.2 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Nop14 PF04147.12 PSC70241.1 - 0.21 9.8 14.5 0.29 9.3 14.5 1.1 1 0 0 1 1 1 0 Nop14-like family LAP1C PF05609.12 PSC70241.1 - 3.7 6.5 13.9 4.6 6.2 13.9 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 PSC70241.1 - 5.5 5.4 12.5 7.2 5.0 12.5 1.2 1 0 0 1 1 1 0 Macoilin family SDA1 PF05285.12 PSC70241.1 - 5.8 6.2 23.0 0.4 10.1 17.7 1.6 2 0 0 2 2 2 0 SDA1 PPP4R2 PF09184.11 PSC70241.1 - 7.1 6.1 13.4 12 5.3 13.4 1.3 1 0 0 1 1 1 0 PPP4R2 SAPS PF04499.15 PSC70241.1 - 8.4 5.0 6.3 9.1 4.9 6.3 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Pkinase_Tyr PF07714.17 PSC70242.1 - 1.3e-51 175.4 0.0 2.5e-51 174.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC70242.1 - 4.6e-42 144.2 0.0 6.2e-42 143.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LRRNT_2 PF08263.12 PSC70242.1 - 2.5e-11 43.7 2.6 5.5e-11 42.6 2.6 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain Kinase-like PF14531.6 PSC70242.1 - 0.0011 18.4 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PSC70242.1 - 0.065 12.2 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 PSC70242.1 - 0.066 13.1 1.1 0.19 11.7 1.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family LRR_4 PF12799.7 PSC70242.1 - 0.15 12.5 5.7 0.22 12.0 0.1 3.0 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC70242.1 - 1.1 9.1 2.3 0.88 9.4 0.2 1.9 2 0 0 2 2 2 0 Leucine rich repeat DUF4460 PF14687.6 PSC70243.1 - 1.4e-11 44.4 0.0 3.2e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4460) DUF4461 PF14688.6 PSC70243.1 - 1.3e-09 38.3 0.0 1.9e-06 27.9 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4461) BACK PF07707.15 PSC70244.1 - 5.9e-14 52.0 0.0 9.8e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 BTB And C-terminal Kelch eIF3_N PF09440.10 PSC70245.1 - 6.4e-48 162.6 0.8 2.9e-47 160.4 0.1 2.2 2 0 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 PSC70245.1 - 1e-14 54.9 0.2 3.4e-14 53.2 0.0 2.0 2 1 0 2 2 2 1 PCI domain EF_assoc_1 PF08355.12 PSC70245.1 - 0.067 12.8 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 EF hand associated DUF3493 PF11998.8 PSC70246.1 - 4.8e-22 77.9 0.3 1.2e-21 76.7 0.3 1.7 1 0 0 1 1 1 1 Low psii accumulation1 / Rep27 TPR_2 PF07719.17 PSC70246.1 - 0.004 17.2 3.6 0.27 11.4 0.7 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat PH_8 PF15409.6 PSC70246.1 - 0.0075 16.5 1.3 0.017 15.4 1.3 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain TPR_16 PF13432.6 PSC70246.1 - 0.0081 16.8 7.3 0.0081 16.8 7.3 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 PSC70246.1 - 0.014 15.3 0.7 0.13 12.3 0.2 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 PSC70246.1 - 0.019 15.6 3.4 2.1 9.2 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat Methyltransf_34 PF11312.8 PSC70246.1 - 0.04 13.2 0.7 0.09 12.0 0.2 1.8 2 0 0 2 2 2 0 Putative SAM-dependent methyltransferase TPR_14 PF13428.6 PSC70246.1 - 0.12 13.3 5.8 0.95 10.5 2.1 3.4 1 1 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 PSC70246.1 - 0.15 12.5 3.9 0.51 10.9 3.9 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 PSC70246.1 - 0.19 11.6 1.3 6 6.9 0.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 PSC70246.1 - 0.71 10.1 9.7 3.4 7.9 0.6 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 PSC70246.1 - 1.4 9.2 5.9 1 9.7 3.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat WSD PF15613.6 PSC70247.1 - 6.9e-10 39.3 0.0 2.4e-09 37.5 0.0 2.0 1 0 0 1 1 1 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif PHD PF00628.29 PSC70247.1 - 4.5e-08 32.8 7.3 7.6e-08 32.1 7.3 1.4 1 0 0 1 1 1 1 PHD-finger MBD PF01429.19 PSC70247.1 - 3.4e-07 29.9 0.1 1.1e-06 28.2 0.1 1.8 1 0 0 1 1 1 1 Methyl-CpG binding domain FYRC PF05965.14 PSC70247.1 - 0.0021 18.2 0.0 0.006 16.7 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus WHIM1 PF15612.6 PSC70247.1 - 0.032 13.8 0.1 0.087 12.4 0.1 1.7 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 FYRN PF05964.14 PSC70247.1 - 0.039 13.8 0.0 0.078 12.8 0.0 1.4 1 0 0 1 1 1 0 F/Y-rich N-terminus DUF4461 PF14688.6 PSC70247.1 - 0.087 12.6 0.1 0.25 11.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4461) DDT PF02791.17 PSC70247.1 - 0.13 12.6 0.0 0.37 11.1 0.0 1.8 1 0 0 1 1 1 0 DDT domain ADIP PF11559.8 PSC70247.1 - 0.47 10.5 8.0 2 8.5 5.8 2.5 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding C1_2 PF03107.16 PSC70247.1 - 4.3 7.7 6.3 0.81 10.1 1.7 2.1 3 0 0 3 3 3 0 C1 domain Spc7 PF08317.11 PSC70248.1 - 0.00021 20.3 3.8 0.00026 20.0 3.8 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Cluap1 PF10234.9 PSC70248.1 - 0.044 13.2 2.8 0.057 12.8 2.8 1.2 1 0 0 1 1 1 0 Clusterin-associated protein-1 Rab_bind PF16704.5 PSC70248.1 - 0.052 13.6 0.6 0.89 9.6 0.1 2.3 2 0 0 2 2 2 0 Rab binding domain ZYG-11_interact PF05884.12 PSC70248.1 - 0.066 12.6 1.8 0.08 12.3 1.8 1.0 1 0 0 1 1 1 0 Interactor of ZYG-11 Muted PF14942.6 PSC70248.1 - 0.27 11.6 3.3 0.36 11.2 3.3 1.1 1 0 0 1 1 1 0 Organelle biogenesis, Muted-like protein ZapB PF06005.12 PSC70248.1 - 0.37 11.3 4.7 6.8 7.2 4.6 2.2 1 1 0 1 1 1 0 Cell division protein ZapB HAUS-augmin3 PF14932.6 PSC70248.1 - 0.58 9.7 6.6 0.72 9.4 6.6 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Nnf1 PF03980.14 PSC70248.1 - 0.8 10.1 9.6 0.61 10.5 5.4 2.1 2 0 0 2 2 2 0 Nnf1 DUF4140 PF13600.6 PSC70248.1 - 1 9.9 10.3 2.2 8.8 0.2 2.5 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF4407 PF14362.6 PSC70248.1 - 1.1 8.6 13.7 0.3 10.4 9.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF1690 PF07956.11 PSC70248.1 - 4.5 7.7 8.5 6.8 7.1 6.2 1.9 1 1 1 2 2 2 0 Protein of Unknown function (DUF1690) Spectrin PF00435.21 PSC70248.1 - 5.3 7.6 10.3 4.1 7.9 6.0 2.0 1 1 1 2 2 2 0 Spectrin repeat DUF3584 PF12128.8 PSC70248.1 - 5.3 4.4 11.2 6.1 4.2 11.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) TRAPP PF04051.16 PSC70249.1 - 2.6e-43 147.2 0.0 2.9e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Sigma70_r2 PF04542.14 PSC70250.1 - 1.3e-19 69.7 0.2 6.2e-19 67.5 0.0 2.4 2 0 0 2 2 2 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 PSC70250.1 - 5.1e-17 61.1 1.3 1.5e-16 59.7 1.3 1.9 1 0 0 1 1 1 1 Sigma-70, region 4 Sigma70_r1_2 PF00140.20 PSC70250.1 - 9.2e-06 25.6 0.0 2.3e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Sigma-70 factor, region 1.2 Sigma70_r3 PF04539.16 PSC70250.1 - 2.7e-05 24.2 7.4 0.00025 21.1 0.0 3.9 4 0 0 4 4 4 1 Sigma-70 region 3 GOLGA2L5 PF15070.6 PSC70250.1 - 0.0014 17.4 4.1 0.0026 16.5 4.1 1.3 1 0 0 1 1 1 1 Putative golgin subfamily A member 2-like protein 5 DUF755 PF05501.11 PSC70250.1 - 0.0019 18.5 4.1 0.0047 17.2 4.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF755) Med2 PF11214.8 PSC70250.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Mediator complex subunit 2 Macoilin PF09726.9 PSC70250.1 - 0.34 9.4 5.6 0.52 8.8 5.6 1.2 1 0 0 1 1 1 0 Macoilin family Rrn6 PF10214.9 PSC70250.1 - 2.5 6.5 8.9 3.6 6.0 8.9 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SRP-alpha_N PF04086.13 PSC70250.1 - 3.9 7.3 12.4 6.5 6.6 12.4 1.3 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Cep57_CLD PF14073.6 PSC70251.1 - 0.014 15.4 6.4 0.025 14.6 6.4 1.3 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 DDE_Tnp_1_2 PF13586.6 PSC70251.1 - 0.072 13.5 5.3 0.13 12.6 3.2 2.5 2 0 0 2 2 2 0 Transposase DDE domain Lipase_3 PF01764.25 PSC70252.1 - 2.8e-15 56.4 0.0 4.5e-15 55.8 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.20 PSC70252.1 - 0.055 13.6 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Peptidase_S8 PF00082.22 PSC70253.1 - 3.5e-35 121.7 0.0 5.9e-35 121.0 0.0 1.3 1 0 0 1 1 1 1 Subtilase family Pyrid_oxidase_2 PF13883.6 PSC70253.1 - 2.9e-16 59.9 0.0 6.2e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 PSC70253.1 - 3.4e-08 33.6 0.0 9.8e-08 32.1 0.0 1.8 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RNase_PH PF01138.21 PSC70255.1 - 2.7e-36 125.0 0.2 3.7e-36 124.5 0.2 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PSC70255.1 - 0.0017 18.3 0.0 0.0033 17.4 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 UbiA PF01040.18 PSC70256.1 - 5.1e-37 127.5 24.3 6.3e-37 127.2 24.3 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family PRP38_assoc PF12871.7 PSC70257.1 - 6.5 7.4 12.9 0.2 12.3 5.4 2.1 2 1 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term RNase_HII PF01351.18 PSC70258.1 - 2.4e-36 125.5 0.0 3.4e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII DUF4772 PF15997.5 PSC70260.1 - 0.072 13.7 0.0 0.39 11.3 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4772) Pectate_lyase_3 PF12708.7 PSC70261.1 - 0.0029 17.5 0.0 1 9.2 0.0 2.3 2 0 0 2 2 2 2 Pectate lyase superfamily protein Rossmann-like PF10727.9 PSC70262.1 - 0.0062 16.4 0.0 0.0084 16.0 0.0 1.2 1 0 0 1 1 1 1 Rossmann-like domain RAP1 PF07218.11 PSC70262.1 - 0.87 7.8 1.3 1 7.6 1.3 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Glyco_hydro_99 PF16317.5 PSC70263.1 - 5.4e-108 361.2 0.0 3.3e-107 358.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 99 Glyco_hydro_71 PF03659.14 PSC70263.1 - 0.0028 16.6 0.0 0.0044 15.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 71 Glyco_tran_WbsX PF14307.6 PSC70263.1 - 0.0099 15.4 0.2 0.015 14.7 0.2 1.2 1 0 0 1 1 1 1 Glycosyltransferase WbsX DnaJ PF00226.31 PSC70264.1 - 4.6e-23 81.1 0.1 4.6e-23 81.1 0.1 2.0 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 PSC70264.1 - 4.6e-10 39.5 2.2 4.6e-10 39.5 2.2 2.4 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PSC70264.1 - 2.5e-08 34.0 8.1 1.2e-07 31.8 1.9 2.6 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 PSC70264.1 - 0.00049 20.7 7.4 0.016 16.0 1.2 2.5 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.7 PSC70264.1 - 0.00053 20.3 2.8 0.096 13.0 0.2 2.6 2 0 0 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2 PF00096.26 PSC70264.1 - 0.81 10.3 8.6 2.3 8.8 1.0 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type PMI_typeI PF01238.21 PSC70267.1 - 1e-77 261.9 0.0 1.2e-77 261.7 0.0 1.0 1 0 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 PSC70267.1 - 5.3e-05 22.9 0.0 0.41 10.4 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 PSC70267.1 - 0.00095 19.1 0.0 1.8 8.5 0.0 2.9 3 0 0 3 3 3 2 AraC-like ligand binding domain Cupin_6 PF12852.7 PSC70267.1 - 0.0045 16.7 6.1 0.032 14.0 0.2 3.0 2 1 1 3 3 3 1 Cupin Cupin_3 PF05899.12 PSC70267.1 - 0.16 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF861) Glyco_hydro_20 PF00728.22 PSC70268.1 - 5.2e-78 262.9 0.0 6.3e-78 262.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glyco_hydro_20b PF02838.15 PSC70268.1 - 7.1e-07 30.0 0.0 3.3e-06 27.9 0.0 2.1 2 0 0 2 2 2 1 Glycosyl hydrolase family 20, domain 2 Glycohydro_20b2 PF14845.6 PSC70268.1 - 0.0008 20.1 0.0 0.003 18.2 0.0 1.9 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Spindle_Spc25 PF08234.12 PSC70269.1 - 1.3e-16 60.5 0.0 2.7e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 Glyco_tranf_2_4 PF13704.6 PSC70269.1 - 0.00091 19.7 0.1 0.004 17.7 0.1 2.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Spc7 PF08317.11 PSC70269.1 - 0.019 13.9 3.2 0.028 13.3 3.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Herpes_UL25 PF01499.16 PSC70269.1 - 1.2 7.6 3.9 1.7 7.1 3.9 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family AAA_33 PF13671.6 PSC70270.1 - 2.1e-05 24.7 0.0 2.1e-05 24.7 0.0 2.6 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 PSC70270.1 - 0.0067 15.7 0.6 0.058 12.7 0.0 2.6 3 0 0 3 3 3 1 Zeta toxin AAA_16 PF13191.6 PSC70270.1 - 0.009 16.4 0.0 0.009 16.4 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain AAA_18 PF13238.6 PSC70270.1 - 0.011 16.3 0.8 0.038 14.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain YabA PF06156.13 PSC70270.1 - 0.037 14.7 1.0 0.037 14.7 1.0 2.9 3 0 0 3 3 3 0 Initiation control protein YabA Shugoshin_N PF07558.11 PSC70270.1 - 0.14 12.0 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Shugoshin N-terminal coiled-coil region AAA_22 PF13401.6 PSC70270.1 - 0.17 12.1 1.2 0.53 10.6 0.0 2.3 2 1 0 2 2 2 0 AAA domain PAT1 PF09770.9 PSC70270.1 - 0.38 9.0 24.9 0.33 9.2 0.0 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 RBR PF17208.3 PSC70271.1 - 0.28 11.9 0.2 0.28 11.9 0.2 2.2 2 0 0 2 2 2 0 RNA binding Region 3HCDH_N PF02737.18 PSC70272.1 - 8.8e-60 201.7 0.2 1.1e-59 201.3 0.2 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 PSC70272.1 - 9.2e-34 116.0 0.0 3.6e-33 114.0 0.0 2.0 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 PSC70272.1 - 5.7e-05 23.3 0.5 0.00013 22.2 0.5 1.6 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 PSC70272.1 - 0.0015 17.9 0.6 0.0099 15.3 0.2 2.0 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 PSC70272.1 - 0.0022 18.0 0.0 0.0042 17.1 0.0 1.4 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus F420_oxidored PF03807.17 PSC70272.1 - 0.0038 17.8 1.7 0.013 16.1 1.6 2.0 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent FAD_binding_2 PF00890.24 PSC70272.1 - 0.0083 15.2 0.7 0.0095 15.0 0.7 1.1 1 0 0 1 1 1 1 FAD binding domain XdhC_C PF13478.6 PSC70272.1 - 0.015 15.8 2.5 0.039 14.5 2.0 2.0 2 1 0 2 2 2 0 XdhC Rossmann domain Pyr_redox_2 PF07992.14 PSC70272.1 - 0.023 14.0 0.3 0.087 12.0 0.2 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PSC70272.1 - 0.03 13.9 0.2 0.035 13.7 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase DFP PF04127.15 PSC70272.1 - 0.055 13.3 0.7 0.098 12.5 0.7 1.3 1 0 0 1 1 1 0 DNA / pantothenate metabolism flavoprotein UDPG_MGDP_dh_N PF03721.14 PSC70272.1 - 0.062 12.9 0.2 0.14 11.7 0.2 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain MtrH PF02007.18 PSC70272.1 - 0.078 12.1 0.2 0.12 11.5 0.2 1.2 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase MtrH subunit Polysacc_synt_4 PF04669.13 PSC70273.1 - 3.4e-20 72.4 0.1 2.3e-18 66.4 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide biosynthesis GATA PF00320.27 PSC70274.1 - 6.5e-08 32.0 1.8 6.5e-08 32.0 1.8 1.8 2 0 0 2 2 2 1 GATA zinc finger zf-C3HC4 PF00097.25 PSC70275.1 - 0.037 13.9 7.9 0.27 11.2 8.5 1.9 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF2116 PF09889.9 PSC70275.1 - 0.037 14.0 0.6 0.037 14.0 0.6 3.0 3 1 1 4 4 4 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) SUIM_assoc PF16619.5 PSC70275.1 - 0.066 13.3 5.4 0.12 12.4 5.4 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Fer2_3 PF13085.6 PSC70275.1 - 0.071 13.1 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain Prok-RING_4 PF14447.6 PSC70275.1 - 0.54 10.2 10.2 0.9 9.4 10.2 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PSC70275.1 - 1.2 9.5 12.3 4.2 7.8 12.5 1.7 1 1 1 2 2 2 0 Ring finger domain zf-RING_5 PF14634.6 PSC70275.1 - 2.4 8.2 15.9 9.2 6.3 15.8 1.9 1 1 1 2 2 2 0 zinc-RING finger domain DUF1118 PF06549.12 PSC70276.1 - 2.6e-41 140.5 4.4 4.1e-41 139.9 4.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1118) PIG-H PF10181.9 PSC70277.1 - 4.7e-09 36.0 0.0 2e-08 34.0 0.0 1.9 2 0 0 2 2 2 1 GPI-GlcNAc transferase complex, PIG-H component Phage_holin_5_1 PF06946.11 PSC70277.1 - 0.48 10.8 4.8 0.93 9.9 4.8 1.4 1 0 0 1 1 1 0 Bacteriophage A118-like holin, Hol118 UPF0565 PF10561.9 PSC70278.1 - 0.0014 17.9 0.0 0.21 10.7 0.0 2.6 3 0 0 3 3 3 2 Uncharacterised protein family UPF0565 SUIM_assoc PF16619.5 PSC70278.1 - 4.6 7.4 10.3 8.2 6.6 2.1 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 UPF0565 PF10561.9 PSC70279.1 - 0.0015 17.8 0.0 0.22 10.7 0.0 2.6 3 0 0 3 3 3 2 Uncharacterised protein family UPF0565 SUIM_assoc PF16619.5 PSC70279.1 - 4.7 7.3 10.3 8.3 6.6 2.1 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HECT PF00632.25 PSC70280.1 - 4.5e-71 239.8 0.0 6.3e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 PSC70280.1 - 1.5 9.0 10.8 30 4.8 0.0 6.2 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat HECT PF00632.25 PSC70281.1 - 4.5e-71 239.8 0.0 6.3e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 PSC70281.1 - 1.5 9.0 10.8 30 4.8 0.0 6.2 8 0 0 8 8 8 0 Armadillo/beta-catenin-like repeat EamA PF00892.20 PSC70282.1 - 1.4e-20 73.9 16.8 1.3e-11 44.8 5.4 2.5 2 0 0 2 2 2 2 EamA-like transporter family Abhydrolase_1 PF00561.20 PSC70282.1 - 1.5e-12 47.7 0.2 2.6e-12 47.0 0.2 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC70282.1 - 2.2e-06 27.1 0.0 3.8e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 TPT PF03151.16 PSC70282.1 - 0.046 13.1 0.2 0.11 11.8 0.2 1.6 1 1 0 1 1 1 0 Triose-phosphate Transporter family Kinesin PF00225.23 PSC70283.1 - 7.1e-100 334.2 0.1 9.8e-100 333.7 0.1 1.2 1 0 0 1 1 1 1 Kinesin motor domain Peptidase_S8 PF00082.22 PSC70283.1 - 3.1e-44 151.4 1.3 1.5e-43 149.1 0.4 2.4 3 0 0 3 3 3 1 Subtilase family Microtub_bd PF16796.5 PSC70283.1 - 1.1e-24 87.1 0.0 2.7e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 Microtubule binding K-box PF01486.17 PSC70283.1 - 0.00029 21.0 2.7 0.00029 21.0 2.7 3.3 4 0 0 4 4 4 1 K-box region HTH_Crp_2 PF13545.6 PSC70283.1 - 0.063 13.3 1.5 1.8 8.6 0.5 2.9 1 1 1 2 2 2 0 Crp-like helix-turn-helix domain Macoilin PF09726.9 PSC70283.1 - 0.28 9.7 4.5 3.4 6.1 0.2 2.4 2 0 0 2 2 2 0 Macoilin family TMF_TATA_bd PF12325.8 PSC70283.1 - 0.59 10.4 8.0 0.07 13.4 0.5 3.1 2 2 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Fzo_mitofusin PF04799.13 PSC70283.1 - 2 8.0 4.1 1.3 8.6 1.2 2.0 2 0 0 2 2 2 0 fzo-like conserved region CCDC144C PF14915.6 PSC70283.1 - 2.7 7.0 15.6 0.14 11.2 2.9 3.1 3 0 0 3 3 3 0 CCDC144C protein coiled-coil region Fungal_TACC PF12709.7 PSC70283.1 - 6.7 7.2 7.4 5.4 7.5 0.4 3.5 3 1 1 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins Mur_ligase_M PF08245.12 PSC70284.1 - 2.5e-08 34.1 0.0 5e-06 26.6 0.0 2.8 1 1 0 1 1 1 1 Mur ligase middle domain DUF2722 PF10846.8 PSC70284.1 - 0.00084 18.4 12.3 0.0013 17.8 12.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 PSC70284.1 - 0.0063 16.6 18.4 0.0089 16.1 18.4 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit FTO_NTD PF12933.7 PSC70284.1 - 0.045 13.0 0.6 0.076 12.3 0.6 1.3 1 0 0 1 1 1 0 FTO catalytic domain Med15 PF09606.10 PSC70284.1 - 0.062 12.0 31.5 0.089 11.5 31.5 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CCDC53 PF10152.9 PSC70284.1 - 0.14 12.6 7.3 0.31 11.4 7.3 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex eIF-3_zeta PF05091.12 PSC70284.1 - 0.26 10.2 4.1 0.34 9.9 4.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF4407 PF14362.6 PSC70284.1 - 0.26 10.6 6.2 0.48 9.7 6.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Suf PF05843.14 PSC70284.1 - 0.37 10.7 10.1 0.57 10.1 10.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Kei1 PF08552.11 PSC70284.1 - 0.4 10.5 2.2 0.76 9.6 2.2 1.4 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Presenilin PF01080.17 PSC70284.1 - 0.54 9.0 3.3 0.31 9.7 1.7 1.4 2 0 0 2 2 2 0 Presenilin DUF2229 PF09989.9 PSC70284.1 - 0.59 9.7 2.9 0.98 9.0 0.0 2.1 2 0 0 2 2 2 0 CoA enzyme activase uncharacterised domain (DUF2229) UPF0560 PF10577.9 PSC70284.1 - 0.66 8.4 6.2 0.91 7.9 6.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Ndc1_Nup PF09531.10 PSC70284.1 - 2.4 6.7 8.5 3.3 6.3 8.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Radical_SAM_N PF08497.10 PSC70284.1 - 2.6 7.2 4.5 2.7 7.2 0.0 2.2 2 0 0 2 2 2 0 Radical SAM N-terminal DUF3464 PF11947.8 PSC70284.1 - 3.3 7.5 5.6 7 6.4 5.6 1.5 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Spt20 PF12090.8 PSC70284.1 - 7.2 6.2 31.3 0.41 10.2 26.0 1.5 2 0 0 2 2 2 0 Spt20 family DUF4834 PF16118.5 PSC70284.1 - 8.7 7.4 8.4 18 6.3 8.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Ank_4 PF13637.6 PSC70286.1 - 0.12 13.0 0.1 1.7 9.3 0.0 2.7 2 1 1 3 3 3 0 Ankyrin repeats (many copies) KfrA_N PF11740.8 PSC70286.1 - 2.2 9.0 15.1 3 8.5 2.3 3.4 3 1 0 3 3 3 0 Plasmid replication region DNA-binding N-term Complex1_LYR PF05347.15 PSC70288.1 - 2.4e-12 46.7 1.9 3.1e-12 46.4 1.9 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 PSC70288.1 - 0.0012 19.6 0.0 0.0014 19.3 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 PSC70288.1 - 0.11 13.2 2.5 4.2 8.0 0.1 2.1 1 1 1 2 2 2 0 Complex1_LYR-like AAL_decarboxy PF03306.13 PSC70289.1 - 8.4e-59 198.5 0.0 1.2e-58 198.0 0.0 1.2 1 0 0 1 1 1 1 Alpha-acetolactate decarboxylase DUF493 PF04359.14 PSC70289.1 - 2.6e-12 47.2 0.2 1.1e-11 45.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF493) HIG_1_N PF04588.13 PSC70290.1 - 7.6e-16 58.1 2.7 1.2e-15 57.4 2.7 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region RBFA PF02033.18 PSC70290.1 - 2.6e-07 31.0 0.2 6.5e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 Ribosome-binding factor A YL1 PF05764.13 PSC70290.1 - 0.018 15.1 2.0 0.026 14.7 2.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Ald_Xan_dh_C PF01315.22 PSC70290.1 - 0.34 11.3 2.8 16 5.9 0.1 2.3 2 0 0 2 2 2 0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain DUF883 PF05957.13 PSC70290.1 - 0.86 10.2 0.1 0.86 10.2 0.1 3.2 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF883) ARID PF01388.21 PSC70291.1 - 3.1e-12 47.0 0.0 6.1e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain PHD PF00628.29 PSC70291.1 - 8e-08 32.1 5.6 1.4e-07 31.3 5.6 1.4 1 0 0 1 1 1 1 PHD-finger PHD_Oberon PF07227.11 PSC70291.1 - 0.0024 17.8 2.9 0.0044 16.9 2.9 1.3 1 0 0 1 1 1 1 PHD - plant homeodomain finger protein Prok-RING_1 PF14446.6 PSC70291.1 - 0.6 10.1 6.9 0.06 13.3 2.3 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Zn_Tnp_IS91 PF14319.6 PSC70291.1 - 1.1 9.4 7.6 1.1e+02 3.0 7.6 2.3 1 1 0 1 1 1 0 Transposase zinc-binding domain C1_2 PF03107.16 PSC70291.1 - 2.5 8.5 6.1 2.1 8.7 2.0 2.3 2 0 0 2 2 2 0 C1 domain IBR PF01485.21 PSC70292.1 - 8.6e-22 77.1 52.7 1.6e-12 47.4 6.5 5.3 4 1 0 5 5 5 3 IBR domain, a half RING-finger domain RWD PF05773.22 PSC70292.1 - 5.7e-19 68.5 0.0 1.4e-18 67.2 0.0 1.7 1 1 0 1 1 1 1 RWD domain zinc_ribbon_2 PF13240.6 PSC70292.1 - 0.45 10.3 0.1 0.45 10.3 0.1 8.2 9 1 1 10 10 10 0 zinc-ribbon domain IF-2B PF01008.17 PSC70293.1 - 4.5e-72 242.6 0.0 6.9e-72 242.0 0.0 1.3 1 0 0 1 1 1 1 Initiation factor 2 subunit family DSPc PF00782.20 PSC70293.1 - 2.7e-32 111.4 0.0 5.1e-32 110.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain FHA PF00498.26 PSC70293.1 - 2.7e-15 56.5 0.0 5.6e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 PSC70293.1 - 1.5e-08 34.8 0.0 3.1e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Rhodanese PF00581.20 PSC70293.1 - 2.9e-06 27.8 0.3 0.00011 22.7 0.0 3.0 3 0 0 3 3 3 1 Rhodanese-like domain Y_phosphatase PF00102.27 PSC70293.1 - 0.0017 18.0 0.0 0.0029 17.2 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 PSC70293.1 - 0.038 14.3 0.1 0.14 12.4 0.0 2.0 2 0 0 2 2 2 0 Rit1 DUSP-like domain PRP38_assoc PF12871.7 PSC70293.1 - 0.34 11.5 41.1 0.92 10.2 41.1 1.7 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF4106 PF13388.6 PSC70293.1 - 4 6.6 8.3 9.4 5.4 8.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) RSRP PF17069.5 PSC70293.1 - 7.8 6.0 28.5 13 5.2 28.5 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 Lipase_3 PF01764.25 PSC70294.1 - 9.8e-16 57.9 0.0 2.6e-15 56.5 0.0 1.7 1 1 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 PSC70294.1 - 0.013 15.2 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Hydrolase_4 PF12146.8 PSC70294.1 - 1 8.6 7.9 0.12 11.6 0.3 2.5 1 1 1 2 2 2 0 Serine aminopeptidase, S33 TFIIA PF03153.13 PSC70294.1 - 6.7 6.6 11.6 14 5.5 11.7 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Bromodomain PF00439.25 PSC70295.1 - 1.8e-20 72.8 0.0 3.3e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 PSC70295.1 - 1.3e-07 31.6 0.0 2.6e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Neur_chan_memb PF02932.16 PSC70295.1 - 0.014 15.5 4.2 0.022 14.8 4.2 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CPSF100_C PF13299.6 PSC70295.1 - 0.022 14.9 10.2 0.06 13.5 10.2 1.7 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Velvet PF11754.8 PSC70295.1 - 0.12 12.3 10.1 0.24 11.3 10.1 1.5 1 0 0 1 1 1 0 Velvet factor Exonuc_VII_L PF02601.15 PSC70295.1 - 1.1 8.8 19.0 0.047 13.2 11.0 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit Folliculin PF11704.8 PSC70295.1 - 1.6 8.6 22.0 0.79 9.6 18.2 2.3 3 0 0 3 3 3 0 Vesicle coat protein involved in Golgi to plasma membrane transport AUX_IAA PF02309.16 PSC70295.1 - 2.1 8.1 7.7 4.4 7.1 7.7 1.5 1 0 0 1 1 1 0 AUX/IAA family FAM60A PF15396.6 PSC70295.1 - 2.8 7.9 13.6 5.8 6.8 13.6 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Med24_N PF11277.8 PSC70295.1 - 3.3 5.6 10.0 4.6 5.2 10.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal PAT1 PF09770.9 PSC70295.1 - 4.8 5.3 31.0 11 4.2 31.0 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF966 PF06136.13 PSC70295.1 - 6.7 6.3 12.4 14 5.3 12.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Presenilin PF01080.17 PSC70295.1 - 6.8 5.3 22.0 12 4.5 22.0 1.3 1 0 0 1 1 1 0 Presenilin FHIPEP PF00771.20 PSC70295.1 - 6.8 5.0 10.7 14 4.0 10.7 1.4 1 0 0 1 1 1 0 FHIPEP family Sec62 PF03839.16 PSC70295.1 - 7.8 5.9 13.1 13 5.2 13.1 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 SLC12 PF03522.15 PSC70295.1 - 8.8 5.2 16.1 15 4.5 16.1 1.3 1 0 0 1 1 1 0 Solute carrier family 12 SpoIIP PF07454.11 PSC70295.1 - 9.5 5.6 12.8 18 4.7 12.8 1.4 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Usp PF00582.26 PSC70296.1 - 1.8e-21 77.1 0.9 8.3e-21 75.0 0.9 1.8 1 1 0 1 1 1 1 Universal stress protein family zf-C3HC4 PF00097.25 PSC70297.1 - 6.2e-09 35.6 3.5 1e-08 34.9 3.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC70297.1 - 8.1e-09 35.2 3.2 1.4e-08 34.5 3.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PSC70297.1 - 3.8e-08 33.1 5.1 6e-08 32.4 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC70297.1 - 7.1e-06 26.3 6.6 1.2e-05 25.5 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PSC70297.1 - 8.8e-06 25.6 4.2 1.5e-05 24.9 4.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PSC70297.1 - 1.3e-05 25.3 6.7 2.1e-05 24.6 6.7 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 PSC70297.1 - 1.5e-05 24.9 6.3 3.2e-05 23.8 6.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PSC70297.1 - 0.00027 20.7 6.5 0.0005 19.9 6.5 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 PSC70297.1 - 0.0014 18.4 1.1 0.0033 17.2 1.1 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 PSC70297.1 - 0.0029 17.9 2.2 0.0067 16.7 2.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 PSC70297.1 - 0.0037 17.3 5.9 0.0066 16.6 5.9 1.4 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 PSC70297.1 - 0.011 15.8 0.7 0.02 14.9 0.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger U-box PF04564.15 PSC70297.1 - 0.042 14.0 0.0 0.074 13.2 0.0 1.4 1 0 0 1 1 1 0 U-box domain Actin PF00022.19 PSC70298.1 - 1.9e-78 263.9 0.0 1.1e-77 261.3 0.0 1.8 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 PSC70298.1 - 0.00027 19.9 0.0 0.072 11.9 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Dicer_dimer PF03368.14 PSC70298.1 - 0.13 12.4 0.1 0.23 11.6 0.1 1.4 1 0 0 1 1 1 0 Dicer dimerisation domain AI-2E_transport PF01594.16 PSC70299.1 - 2.5e-33 115.7 22.1 3.7e-33 115.1 22.1 1.3 1 0 0 1 1 1 1 AI-2E family transporter DnaJ PF00226.31 PSC70299.1 - 3.8e-06 26.9 0.0 6.8e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF4880 PF16220.5 PSC70299.1 - 0.00043 20.1 0.4 0.0043 16.9 0.4 2.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4880) FLILHELTA PF10306.9 PSC70299.1 - 0.11 12.9 0.1 2.3 8.7 0.0 2.8 3 0 0 3 3 3 0 Hypothetical protein FLILHELTA MCM PF00493.23 PSC70300.1 - 1.2e-80 269.8 0.0 1.8e-80 269.2 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 PSC70300.1 - 3.8e-26 91.3 1.6 6.1e-26 90.7 1.6 1.3 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 PSC70300.1 - 1.1e-21 77.0 2.2 2e-21 76.1 2.2 1.4 1 0 0 1 1 1 1 MCM OB domain AAA_5 PF07728.14 PSC70300.1 - 4.3e-09 36.5 0.0 7.2e-09 35.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 PSC70300.1 - 3.1e-08 33.2 0.2 6.1e-06 25.8 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 PSC70300.1 - 9.7e-06 25.5 0.0 2.7e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Nucleotid_trans PF03407.16 PSC70300.1 - 1.9e-05 24.7 0.0 4.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Sigma54_activat PF00158.26 PSC70300.1 - 0.0012 18.5 0.1 0.011 15.4 0.1 2.1 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA PF00004.29 PSC70300.1 - 0.0032 17.9 0.0 0.0083 16.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PSC70300.1 - 0.018 15.4 2.3 0.068 13.5 0.1 2.9 3 0 0 3 3 3 0 AAA ATPase domain RuvB_N PF05496.12 PSC70300.1 - 0.071 12.9 0.0 0.2 11.4 0.0 1.7 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 PSC70300.1 - 0.1 12.5 0.0 2.7 7.9 0.0 2.8 3 0 0 3 3 3 0 NACHT domain TFIIA PF03153.13 PSC70300.1 - 8.1 6.3 9.3 13 5.7 9.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0506 PF11703.8 PSC70301.1 - 0.00061 20.1 34.0 0.0039 17.5 15.3 3.0 1 1 0 2 2 2 2 UPF0506 Toxin_18 PF08087.11 PSC70301.1 - 0.0036 17.3 6.6 0.0036 17.3 6.6 3.5 3 1 0 3 3 3 1 Conotoxin O-superfamily Toxin_19 PF08088.12 PSC70301.1 - 0.0051 16.9 12.0 0.0051 16.9 12.0 3.4 3 1 0 3 3 3 1 Conotoxin I-superfamily Toxin_29 PF08116.11 PSC70301.1 - 0.011 15.8 8.6 0.011 15.8 8.6 3.7 3 1 0 3 3 3 0 PhTx neurotoxin family Toxin_27 PF08099.11 PSC70301.1 - 0.08 13.1 7.4 0.08 13.1 7.4 3.4 3 0 0 3 3 3 0 Scorpion calcine family Conotoxin_I2 PF17557.2 PSC70301.1 - 6.5 7.0 40.8 0.081 13.1 9.2 3.6 3 1 0 3 3 3 0 I2-superfamily conotoxins DAO PF01266.24 PSC70302.1 - 0.00033 20.4 1.9 0.24 10.9 0.2 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 PSC70302.1 - 0.013 16.1 0.1 0.03 14.9 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PSC70302.1 - 0.031 13.5 0.0 0.053 12.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase SHOCT PF09851.9 PSC70302.1 - 0.17 11.7 0.3 0.35 10.6 0.3 1.5 1 0 0 1 1 1 0 Short C-terminal domain HSP20 PF00011.21 PSC70304.1 - 9.8e-23 80.3 3.2 1.3e-22 79.9 3.2 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PSC70304.1 - 3e-07 29.9 0.5 5.9e-07 29.0 0.5 1.5 1 1 0 1 1 1 1 HSP20-like domain found in ArsA SHOCT PF09851.9 PSC70305.1 - 0.12 12.1 0.7 0.32 10.8 0.7 1.8 1 0 0 1 1 1 0 Short C-terminal domain ABA_GPCR PF12430.8 PSC70306.1 - 1.3e-27 96.7 6.3 1.3e-27 96.7 6.3 2.2 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 PSC70306.1 - 9.3e-20 70.5 0.1 3.8e-19 68.5 0.1 2.1 1 0 0 1 1 1 1 The Golgi pH Regulator (GPHR) Family N-terminal Hrs_helical PF12210.8 PSC70306.1 - 0.41 11.2 2.3 28 5.3 0.0 2.8 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate PALP PF00291.25 PSC70307.1 - 1.2e-66 225.1 2.5 1.5e-66 224.8 2.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 PSC70307.1 - 0.0029 17.6 0.6 0.32 11.0 0.2 2.7 2 1 0 2 2 2 2 Zinc-binding dehydrogenase TPT PF03151.16 PSC70308.1 - 3.6e-21 75.8 16.2 4.5e-21 75.5 16.2 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PSC70308.1 - 1.9e-07 31.4 35.1 0.00021 21.5 19.1 2.9 2 2 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 PSC70308.1 - 0.0068 15.6 0.7 0.0068 15.6 0.7 2.2 2 0 0 2 2 2 1 Nucleotide-sugar transporter PUNUT PF16913.5 PSC70308.1 - 0.045 13.0 17.8 0.049 12.8 6.3 2.2 2 0 0 2 2 2 0 Purine nucleobase transmembrane transport UAA PF08449.11 PSC70308.1 - 0.06 12.5 18.3 0.15 11.2 18.3 1.6 1 1 0 1 1 1 0 UAA transporter family JmjC PF02373.22 PSC70309.1 - 4.4e-38 130.2 0.0 8e-38 129.4 0.0 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase JmjN PF02375.17 PSC70309.1 - 2e-15 56.5 0.7 3.6e-15 55.6 0.7 1.5 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 PSC70309.1 - 4.4e-09 36.6 0.0 9.3e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 C5HC2 zinc finger Otopetrin PF03189.13 PSC70310.1 - 0.63 8.8 10.2 2.9 6.6 10.2 2.1 1 0 0 1 1 1 0 Otopetrin Zip PF02535.22 PSC70310.1 - 0.74 9.0 8.0 2.5 7.2 8.0 1.9 1 0 0 1 1 1 0 ZIP Zinc transporter SMN PF06003.12 PSC70310.1 - 5.7 6.1 17.7 0.035 13.4 8.5 2.0 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) CIA30 PF08547.12 PSC70312.1 - 3.9e-39 134.2 0.0 4.8e-39 134.0 0.0 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) SGBP_B_XBD PF18329.1 PSC70312.1 - 0.0083 16.1 0.0 0.015 15.2 0.0 1.4 1 0 0 1 1 1 1 Surface glycan-binding protein B xyloglucan binding domain CBM_11 PF03425.13 PSC70312.1 - 0.045 13.6 0.0 0.086 12.7 0.0 1.5 1 1 0 1 1 1 0 Carbohydrate binding domain (family 11) Ferritin PF00210.24 PSC70313.1 - 7.5e-23 81.0 0.7 9e-23 80.8 0.7 1.1 1 0 0 1 1 1 1 Ferritin-like domain Rubrerythrin PF02915.17 PSC70313.1 - 0.00053 20.4 0.1 0.002 18.6 0.1 1.9 1 1 1 2 2 2 1 Rubrerythrin CS PF04969.16 PSC70314.1 - 9.3e-17 61.8 0.0 1.7e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 CS domain zf-PARP PF00645.18 PSC70314.1 - 0.16 12.8 0.0 0.45 11.4 0.0 1.7 1 1 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region CS PF04969.16 PSC70315.1 - 9.3e-17 61.8 0.0 1.7e-16 61.0 0.0 1.4 1 0 0 1 1 1 1 CS domain zf-PARP PF00645.18 PSC70315.1 - 0.16 12.8 0.0 0.45 11.4 0.0 1.7 1 1 0 1 1 1 0 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region GMP_synt_C PF00958.22 PSC70316.1 - 5e-41 138.7 0.0 9.9e-41 137.7 0.0 1.5 1 0 0 1 1 1 1 GMP synthase C terminal domain GATase PF00117.28 PSC70316.1 - 2e-34 119.0 0.0 3e-34 118.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 PSC70316.1 - 5.2e-10 39.4 0.1 2.2e-09 37.4 0.1 2.0 2 1 0 2 2 2 1 Peptidase C26 NAD_synthase PF02540.17 PSC70316.1 - 1.8e-09 37.1 0.0 0.00045 19.4 0.0 3.0 3 0 0 3 3 3 2 NAD synthase tRNA_Me_trans PF03054.16 PSC70316.1 - 0.0012 17.7 0.1 0.0021 16.9 0.1 1.3 1 0 0 1 1 1 1 tRNA methyl transferase ThiI PF02568.14 PSC70316.1 - 0.0054 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Thiamine biosynthesis protein (ThiI) PAPS_reduct PF01507.19 PSC70316.1 - 0.031 14.3 0.0 0.056 13.5 0.0 1.4 1 0 0 1 1 1 0 Phosphoadenosine phosphosulfate reductase family QueC PF06508.13 PSC70316.1 - 0.065 12.7 0.0 0.63 9.5 0.0 2.1 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC Peptidase_S9_N PF02897.15 PSC70317.1 - 1.1e-95 320.9 0.0 1.4e-95 320.5 0.0 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 PSC70317.1 - 4.2e-67 225.7 0.0 6.9e-67 225.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 PSC70317.1 - 0.00059 19.2 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ank_2 PF12796.7 PSC70319.1 - 1.9e-16 60.4 1.1 3.1e-08 34.1 0.2 2.4 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC70319.1 - 7.2e-16 58.3 3.4 7.8e-08 32.7 0.0 4.0 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC70319.1 - 2.1e-12 46.1 5.6 0.0033 17.8 0.0 5.4 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 PSC70319.1 - 3.1e-10 40.1 4.0 1.6e-05 25.1 0.2 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PSC70319.1 - 2.2e-07 31.0 9.5 0.0046 17.3 0.1 4.8 4 0 0 4 4 4 2 Ankyrin repeat PhyH PF05721.13 PSC70320.1 - 2.1e-21 77.1 0.1 4.8e-21 76.0 0.1 1.7 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Methyltransf_25 PF13649.6 PSC70320.1 - 4.1e-11 43.4 0.0 1.2e-10 41.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC70320.1 - 8e-08 32.3 0.0 1.4e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC70320.1 - 2e-07 31.7 0.0 5.5e-07 30.2 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC70320.1 - 7.4e-07 29.7 0.0 2.3e-06 28.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC70320.1 - 0.0001 22.2 0.0 0.00016 21.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC70320.1 - 0.0025 17.2 0.0 0.0061 15.9 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 PSC70320.1 - 0.0059 16.7 0.0 0.015 15.4 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_32 PF13679.6 PSC70320.1 - 0.021 14.8 0.0 0.036 14.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 PSC70320.1 - 0.046 13.3 0.1 0.082 12.4 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_2 PF00891.18 PSC70320.1 - 0.13 11.5 0.0 0.22 10.8 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Pyridoxal_deC PF00282.19 PSC70321.1 - 3.2e-22 78.8 0.0 5.4e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain WD40 PF00400.32 PSC70321.1 - 1.4e-14 54.2 0.0 0.018 15.9 0.0 5.5 5 0 0 5 5 4 3 WD domain, G-beta repeat tRNA_U5-meth_tr PF05958.11 PSC70321.1 - 3.7e-12 45.9 0.1 5.5e-11 42.0 0.1 2.1 1 1 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 PSC70321.1 - 8.4e-08 32.1 0.0 1.9e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PSC70321.1 - 5.3e-07 29.3 0.0 1.2e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 PSC70321.1 - 3.5e-06 27.6 0.0 1.6e-05 25.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain TRAM PF01938.20 PSC70321.1 - 7.7e-06 25.8 0.0 1.7e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 TRAM domain Aminotran_5 PF00266.19 PSC70321.1 - 7.8e-06 25.1 0.0 1.5e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class-V ANAPC4_WD40 PF12894.7 PSC70321.1 - 8.7e-05 22.8 0.0 0.003 17.8 0.0 3.0 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_11 PF08241.12 PSC70321.1 - 0.0084 16.7 0.1 0.037 14.7 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Met_10 PF02475.16 PSC70321.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Cons_hypoth95 PF03602.15 PSC70321.1 - 0.012 15.2 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_4 PF02390.17 PSC70321.1 - 0.015 14.8 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DOT1 PF08123.13 PSC70321.1 - 0.017 14.6 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 PrmA PF06325.13 PSC70321.1 - 0.021 14.2 0.5 0.043 13.2 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_32 PF13679.6 PSC70321.1 - 0.28 11.2 7.3 2.6 8.0 0.0 3.6 3 0 0 3 3 3 0 Methyltransferase domain Rieske PF00355.26 PSC70322.1 - 1.2e-09 38.0 0.1 2e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 PSC70322.1 - 1.9e-06 27.7 0.0 3.3e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain FemAB_like PF04339.12 PSC70323.1 - 1.5e-130 435.7 0.0 5.6e-73 246.2 0.0 2.1 2 0 0 2 2 2 2 Peptidogalycan biosysnthesis/recognition PPR_2 PF13041.6 PSC70323.1 - 5.7e-16 58.4 0.0 4.3e-10 39.6 0.0 3.9 3 2 1 4 4 4 2 PPR repeat family PPR_3 PF13812.6 PSC70323.1 - 2e-13 50.2 0.0 0.00015 21.8 0.0 4.8 4 1 0 5 5 5 4 Pentatricopeptide repeat domain Acetyltransf_6 PF13480.7 PSC70323.1 - 1.3e-09 38.3 0.7 1.3e-09 38.3 0.7 3.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain PPR PF01535.20 PSC70323.1 - 3e-08 33.4 0.1 0.0017 18.5 0.0 5.6 5 0 0 5 5 5 1 PPR repeat PPR_1 PF12854.7 PSC70323.1 - 1e-07 31.5 0.1 4.2e-05 23.2 0.0 4.2 6 0 0 6 6 6 1 PPR repeat PPR_long PF17177.4 PSC70323.1 - 3.9e-07 29.7 0.1 4.2e-06 26.3 0.0 2.5 2 1 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP FemAB_like PF04339.12 PSC70324.1 - 1.5e-130 435.7 0.0 5.6e-73 246.2 0.0 2.1 2 0 0 2 2 2 2 Peptidogalycan biosysnthesis/recognition PPR_2 PF13041.6 PSC70324.1 - 5.7e-16 58.4 0.0 4.3e-10 39.6 0.0 3.9 3 2 1 4 4 4 2 PPR repeat family PPR_3 PF13812.6 PSC70324.1 - 1.9e-13 50.2 0.0 0.00015 21.8 0.0 4.8 4 1 0 5 5 5 4 Pentatricopeptide repeat domain Acetyltransf_6 PF13480.7 PSC70324.1 - 1.3e-09 38.3 0.7 1.3e-09 38.3 0.7 3.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain PPR PF01535.20 PSC70324.1 - 3e-08 33.4 0.1 0.0017 18.5 0.0 5.6 5 0 0 5 5 5 1 PPR repeat PPR_1 PF12854.7 PSC70324.1 - 1e-07 31.5 0.1 4.2e-05 23.2 0.0 4.2 6 0 0 6 6 6 1 PPR repeat PPR_long PF17177.4 PSC70324.1 - 3.9e-07 29.7 0.1 4.1e-06 26.3 0.0 2.5 2 1 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP FemAB_like PF04339.12 PSC70325.1 - 1.5e-130 435.7 0.0 5.6e-73 246.2 0.0 2.1 2 0 0 2 2 2 2 Peptidogalycan biosysnthesis/recognition PPR_2 PF13041.6 PSC70325.1 - 5.8e-16 58.4 0.0 4.3e-10 39.6 0.0 3.9 3 2 1 4 4 4 2 PPR repeat family PPR_3 PF13812.6 PSC70325.1 - 1.8e-13 50.3 0.0 0.00015 21.8 0.0 4.8 4 1 0 5 5 5 4 Pentatricopeptide repeat domain Acetyltransf_6 PF13480.7 PSC70325.1 - 1.3e-09 38.3 0.7 1.3e-09 38.3 0.7 3.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain PPR PF01535.20 PSC70325.1 - 2.9e-08 33.4 0.0 0.0017 18.5 0.0 5.6 5 0 0 5 5 5 1 PPR repeat PPR_1 PF12854.7 PSC70325.1 - 1.1e-07 31.5 0.1 4.2e-05 23.1 0.0 4.2 6 0 0 6 6 6 1 PPR repeat PPR_long PF17177.4 PSC70325.1 - 4e-07 29.6 0.2 4.4e-06 26.2 0.1 2.5 2 1 0 2 2 2 1 Pentacotripeptide-repeat region of PRORP TFIIA PF03153.13 PSC70326.1 - 5.4 6.9 11.5 7.7 6.4 11.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 PSC70328.1 - 4.5e-06 27.3 15.1 0.11 13.4 0.1 5.8 5 1 0 5 5 5 4 WD domain, G-beta repeat DEC1 PF15859.5 PSC70328.1 - 0.06 13.4 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Deleted in esophageal cancer 1 family PrmA PF06325.13 PSC70329.1 - 1.2e-09 38.0 0.0 1.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PSC70329.1 - 1.5e-09 38.5 0.0 5e-09 36.7 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 PSC70329.1 - 2.5e-07 30.4 0.0 1.2e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.12 PSC70329.1 - 1.5e-06 28.8 0.0 4.3e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC70329.1 - 6.7e-06 26.0 0.0 2.2e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 PSC70329.1 - 0.0002 20.8 0.0 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.16 PSC70329.1 - 0.00029 20.7 0.0 0.00048 20.0 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.12 PSC70329.1 - 0.00038 21.2 0.0 0.0024 18.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC70329.1 - 0.00053 19.8 0.0 0.0016 18.3 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 PSC70329.1 - 0.0017 18.3 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 PSC70329.1 - 0.0024 16.9 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Met_10 PF02475.16 PSC70329.1 - 0.0095 15.7 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_24 PF13578.6 PSC70329.1 - 0.012 16.6 0.3 0.06 14.4 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain GidB PF02527.15 PSC70329.1 - 0.027 13.8 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G TehB PF03848.14 PSC70329.1 - 0.031 13.7 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 PSC70329.1 - 0.05 13.6 0.6 0.13 12.2 0.0 2.0 3 0 0 3 3 3 0 Methyltransferase domain Cons_hypoth95 PF03602.15 PSC70329.1 - 0.072 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 PrmA PF06325.13 PSC70330.1 - 1.2e-09 38.0 0.0 1.9e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PSC70330.1 - 1.4e-09 38.5 0.0 5e-09 36.7 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.14 PSC70330.1 - 2.5e-07 30.4 0.0 1.3e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.12 PSC70330.1 - 1.5e-06 28.8 0.0 4.3e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC70330.1 - 6.4e-06 26.1 0.0 2.2e-05 24.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 PSC70330.1 - 0.0002 20.8 0.0 0.00032 20.1 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PRMT5 PF05185.16 PSC70330.1 - 0.0003 20.7 0.0 0.00048 20.0 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_12 PF08242.12 PSC70330.1 - 0.00036 21.2 0.0 0.0024 18.6 0.0 2.4 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC70330.1 - 0.00053 19.8 0.0 0.0016 18.3 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 PSC70330.1 - 0.0017 18.3 0.0 0.0029 17.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 PSC70330.1 - 0.0024 16.9 0.0 0.0037 16.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_24 PF13578.6 PSC70330.1 - 0.0079 17.2 0.4 0.06 14.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 PSC70330.1 - 0.0093 15.7 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein GidB PF02527.15 PSC70330.1 - 0.027 13.8 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G TehB PF03848.14 PSC70330.1 - 0.031 13.7 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 PSC70330.1 - 0.038 14.0 0.5 0.13 12.3 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain Cons_hypoth95 PF03602.15 PSC70330.1 - 0.073 12.7 0.1 0.13 11.8 0.1 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Peptidase_C1 PF00112.23 PSC70331.1 - 2.5e-58 197.8 0.2 3.7e-58 197.2 0.2 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Brix PF04427.18 PSC70331.1 - 1.5e-29 103.5 0.1 2.4e-29 102.8 0.1 1.3 1 0 0 1 1 1 1 Brix domain Inhibitor_I29 PF08246.12 PSC70331.1 - 1.1e-07 32.2 0.0 2.2e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Ribosomal_L25p PF01386.19 PSC70331.1 - 0.12 12.9 0.0 0.36 11.4 0.0 1.8 1 0 0 1 1 1 0 Ribosomal L25p family Aph-1 PF06105.12 PSC70332.1 - 7.4e-34 117.1 8.1 8.9e-34 116.9 8.1 1.0 1 0 0 1 1 1 1 Aph-1 protein Abhydrolase_9_N PF15420.6 PSC70332.1 - 0.02 14.9 14.4 0.033 14.2 2.5 2.4 1 1 0 2 2 2 0 Alpha/beta-hydrolase family N-terminus Pribosyltran PF00156.27 PSC70333.1 - 8.7e-25 87.1 0.1 1e-24 86.9 0.1 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 PSC70333.1 - 0.009 15.5 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyl_synth PF14572.6 PSC70333.1 - 0.24 11.4 0.4 0.39 10.7 0.1 1.4 2 0 0 2 2 2 0 Phosphoribosyl synthetase-associated domain Sec34 PF04136.15 PSC70334.1 - 2.2e-42 144.5 0.0 1e-41 142.3 0.0 2.1 2 0 0 2 2 2 1 Sec34-like family ALIX_LYPXL_bnd PF13949.6 PSC70334.1 - 0.028 13.7 0.1 0.06 12.6 0.1 1.5 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV CSN5_C PF18323.1 PSC70334.1 - 0.17 12.8 0.2 5.6 7.9 0.0 2.9 3 0 0 3 3 3 0 Cop9 signalosome subunit 5 C-terminal domain GRAM PF02893.20 PSC70335.1 - 0.00023 21.0 0.0 0.00035 20.4 0.0 1.2 1 0 0 1 1 1 1 GRAM domain tRNA-synt_1b PF00579.25 PSC70338.1 - 7.7e-64 215.8 0.0 9.7e-64 215.5 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) CENP-B_N PF04218.13 PSC70338.1 - 0.053 13.2 0.2 0.27 10.9 0.1 2.3 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain Torsin PF06309.11 PSC70339.1 - 4.7e-10 39.6 0.0 9.6e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Torsin AAA_16 PF13191.6 PSC70339.1 - 6.2e-06 26.7 0.9 0.00061 20.2 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 PSC70339.1 - 0.00016 22.0 0.0 0.0007 19.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 PSC70339.1 - 0.00037 20.9 0.0 0.00072 20.0 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 PSC70339.1 - 0.026 13.7 0.0 0.046 12.9 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain KAP_NTPase PF07693.14 PSC70339.1 - 0.041 13.1 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_5 PF07728.14 PSC70339.1 - 0.076 13.0 0.0 0.17 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 PSC70339.1 - 0.077 13.2 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain TPR_2 PF07719.17 PSC70340.1 - 4.8e-05 23.2 7.0 0.011 15.8 0.1 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 PSC70340.1 - 0.084 13.5 7.6 0.3 11.8 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Ank_2 PF12796.7 PSC70341.1 - 3.8e-22 78.7 0.1 8.5e-13 48.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC70341.1 - 3.8e-18 65.3 3.7 2.1e-07 31.1 0.3 3.6 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC70341.1 - 7.4e-14 51.9 1.2 7.4e-07 29.6 0.1 3.8 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC70341.1 - 1.5e-12 46.5 4.4 0.1 13.2 0.0 5.6 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 PSC70341.1 - 2.2e-10 40.5 13.9 0.0064 16.9 0.0 5.7 6 0 0 6 6 6 4 Ankyrin repeat Kelch_3 PF13415.6 PSC70341.1 - 1.2 9.5 3.2 6.6 7.2 0.1 2.8 3 0 0 3 3 3 0 Galactose oxidase, central domain MMR_HSR1 PF01926.23 PSC70342.1 - 2.2e-37 127.6 0.0 2.3e-17 63.1 0.0 2.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 PSC70342.1 - 9.1e-21 74.0 0.0 2e-20 72.9 0.0 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 PSC70342.1 - 9.9e-15 54.4 0.0 2.3e-06 27.2 0.0 2.8 2 1 0 2 2 2 2 Ferrous iron transport protein B AIG1 PF04548.16 PSC70342.1 - 3.7e-07 29.7 0.0 0.026 13.8 0.0 2.2 2 0 0 2 2 2 2 AIG1 family GTP_EFTU PF00009.27 PSC70342.1 - 8.1e-07 28.8 0.0 0.11 12.1 0.0 5.0 4 2 1 5 5 5 1 Elongation factor Tu GTP binding domain Roc PF08477.13 PSC70342.1 - 7.5e-06 26.2 0.0 0.017 15.3 0.0 3.1 3 2 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PSC70342.1 - 1.8e-05 24.3 0.0 0.0057 16.1 0.0 3.6 3 1 0 3 3 3 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 PSC70342.1 - 0.00037 20.4 0.0 2.3 8.1 0.0 3.4 4 0 0 4 4 4 2 RsgA GTPase Ras PF00071.22 PSC70342.1 - 0.0005 19.7 0.0 2 8.0 0.0 3.3 3 1 0 3 3 3 2 Ras family MeaB PF03308.16 PSC70342.1 - 0.0016 17.5 0.0 11 4.9 0.0 4.0 4 0 0 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 PSC70342.1 - 0.0018 18.8 0.0 0.43 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 PSC70342.1 - 0.006 16.0 0.0 3.3 7.1 0.0 2.6 2 1 0 2 2 2 2 Signal recognition particle receptor beta subunit Dynamin_N PF00350.23 PSC70342.1 - 0.0078 16.3 0.0 16 5.6 0.0 3.6 3 1 1 4 4 4 0 Dynamin family SPX PF03105.19 PSC70342.1 - 0.014 15.3 4.0 0.018 14.9 4.0 1.2 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 PSC70342.1 - 0.026 13.4 5.8 0.034 13.0 5.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain AAA_22 PF13401.6 PSC70342.1 - 0.026 14.8 0.0 3.6 7.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 PSC70342.1 - 0.033 14.7 0.0 4.2 7.9 0.0 2.6 2 0 0 2 2 2 0 ABC transporter RNA_helicase PF00910.22 PSC70342.1 - 0.18 12.2 0.0 25 5.3 0.0 2.4 2 0 0 2 2 2 0 RNA helicase Presenilin PF01080.17 PSC70342.1 - 0.22 10.3 0.9 0.32 9.7 0.9 1.1 1 0 0 1 1 1 0 Presenilin AAA_24 PF13479.6 PSC70342.1 - 0.22 11.2 0.0 25 4.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain Tmemb_cc2 PF10267.9 PSC70342.1 - 1.3 8.1 3.7 1.9 7.5 3.7 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Macoilin PF09726.9 PSC70342.1 - 1.3 7.4 9.8 1.9 6.9 9.8 1.1 1 0 0 1 1 1 0 Macoilin family zf-PARP PF00645.18 PSC70344.1 - 2.7e-21 76.2 0.0 4.5e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region FYRC PF05965.14 PSC70345.1 - 0.022 14.9 4.0 0.027 14.6 0.0 2.9 2 1 0 2 2 2 0 F/Y rich C-terminus HHH PF00633.23 PSC70345.1 - 0.043 13.7 0.0 0.12 12.3 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif DDHD PF02862.17 PSC70345.1 - 0.37 10.9 6.4 0.76 9.9 6.4 1.6 1 0 0 1 1 1 0 DDHD domain Borrelia_P83 PF05262.11 PSC70345.1 - 1.6 7.1 13.5 2.7 6.4 13.5 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein PAT1 PF09770.9 PSC70345.1 - 1.8 6.8 26.6 3 6.0 26.6 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SAPS PF04499.15 PSC70345.1 - 2.2 7.0 8.4 2.9 6.5 8.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Hid1 PF12722.7 PSC70345.1 - 2.2 6.3 13.4 3 5.9 13.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC45 PF02724.14 PSC70345.1 - 8.8 4.5 16.1 13 4.0 16.1 1.1 1 0 0 1 1 1 0 CDC45-like protein SQHop_cyclase_C PF13243.6 PSC70346.1 - 1.3e-57 195.3 0.9 4e-52 177.3 0.4 2.7 2 1 1 3 3 3 3 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 PSC70346.1 - 4.7e-46 157.2 1.0 6.6e-38 130.5 0.1 3.7 3 1 0 3 3 3 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 PSC70346.1 - 1.9e-33 113.9 16.4 3e-10 39.7 1.7 5.9 5 1 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Zip PF02535.22 PSC70346.1 - 1.2e-32 113.5 4.5 1.7e-32 112.9 4.5 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter SQHop_cyclase_C PF13243.6 PSC70347.1 - 1.3e-57 195.4 0.9 3.9e-52 177.3 0.4 2.7 2 1 1 3 3 3 3 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 PSC70347.1 - 5.1e-46 157.1 1.2 6.4e-38 130.5 0.1 3.8 3 1 0 3 3 3 3 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 PSC70347.1 - 1.6e-33 114.1 16.4 2.8e-10 39.7 1.7 5.9 5 1 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat Zip PF02535.22 PSC70347.1 - 7.2e-31 107.6 4.0 1.1e-30 107.0 4.0 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter TPR_16 PF13432.6 PSC70348.1 - 2.4e-07 31.3 18.4 2.4e-07 31.3 18.4 5.4 7 0 0 7 7 7 1 Tetratricopeptide repeat Methyltransf_25 PF13649.6 PSC70348.1 - 0.0043 17.7 0.2 0.036 14.8 0.2 2.7 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 PSC70348.1 - 0.0086 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 PSC70348.1 - 0.046 13.1 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 PSC70348.1 - 0.14 12.0 0.0 0.36 10.6 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_24 PF13578.6 PSC70348.1 - 0.2 12.7 1.0 0.84 10.7 0.0 2.7 3 0 0 3 3 3 0 Methyltransferase domain Herpes_UL52 PF03121.15 PSC70349.1 - 1.5e-12 47.3 0.0 3.6e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase GET2 PF08690.10 PSC70349.1 - 4.3 6.9 8.6 7.4 6.1 8.6 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Herpes_UL52 PF03121.15 PSC70350.1 - 1.5e-12 47.3 0.0 3.6e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Herpesviridae UL52/UL70 DNA primase GET2 PF08690.10 PSC70350.1 - 4.3 6.9 8.6 7.4 6.1 8.6 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Peptidase_A22B PF04258.13 PSC70351.1 - 2.5e-61 207.7 1.2 3.6e-61 207.2 1.2 1.1 1 0 0 1 1 1 1 Signal peptide peptidase PA PF02225.22 PSC70351.1 - 5.3e-07 29.6 1.5 5.3e-07 29.6 1.5 2.0 2 0 0 2 2 2 1 PA domain SPP PF06550.11 PSC70351.1 - 0.59 9.5 4.4 2.9 7.3 3.2 2.3 1 1 0 1 1 1 0 Signal-peptide peptidase, presenilin aspartyl protease SNF2_N PF00176.23 PSC70352.1 - 5.5e-21 74.7 0.5 3e-20 72.2 0.5 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC70352.1 - 1.3e-07 31.9 0.0 2.7e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LON_substr_bdg PF02190.16 PSC70352.1 - 6.2e-07 29.5 0.1 4.7e-06 26.6 0.0 2.5 3 0 0 3 3 3 1 ATP-dependent protease La (LON) substrate-binding domain Asp-B-Hydro_N PF05279.11 PSC70352.1 - 4.6 7.2 17.6 8 6.4 17.6 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CDC27 PF09507.10 PSC70352.1 - 5.4 6.3 21.9 9 5.6 21.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ndc1_Nup PF09531.10 PSC70352.1 - 7 5.2 17.0 13 4.3 17.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SNF2_N PF00176.23 PSC70353.1 - 5.5e-21 74.7 0.5 3e-20 72.2 0.5 1.9 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC70353.1 - 1.3e-07 31.9 0.0 2.7e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LON_substr_bdg PF02190.16 PSC70353.1 - 5e-06 26.5 0.1 3.7e-05 23.7 0.0 2.5 3 0 0 3 3 3 1 ATP-dependent protease La (LON) substrate-binding domain Asp-B-Hydro_N PF05279.11 PSC70353.1 - 4.7 7.2 17.6 8 6.4 17.6 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CDC27 PF09507.10 PSC70353.1 - 5.4 6.3 21.9 9 5.6 21.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ndc1_Nup PF09531.10 PSC70353.1 - 7 5.2 17.0 13 4.3 17.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SNF2_N PF00176.23 PSC70354.1 - 6e-21 74.6 0.6 3.5e-20 72.0 0.6 2.0 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC70354.1 - 1.3e-07 31.9 0.0 2.7e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain LON_substr_bdg PF02190.16 PSC70354.1 - 6.2e-07 29.5 0.1 4.7e-06 26.6 0.0 2.5 3 0 0 3 3 3 1 ATP-dependent protease La (LON) substrate-binding domain Asp-B-Hydro_N PF05279.11 PSC70354.1 - 4.7 7.2 17.6 8 6.4 17.6 1.4 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CDC27 PF09507.10 PSC70354.1 - 5.4 6.3 21.9 9 5.6 21.9 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ndc1_Nup PF09531.10 PSC70354.1 - 7 5.2 17.0 13 4.3 17.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ATP-synt_ab PF00006.25 PSC70355.1 - 2.2e-20 73.3 0.8 1.1e-19 70.9 0.4 2.2 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.27 PSC70355.1 - 1.1e-10 41.9 0.0 4.4e-10 40.0 0.0 1.9 2 0 0 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATPase PF06745.13 PSC70355.1 - 3.9e-05 23.1 0.1 0.00059 19.3 0.1 2.2 2 0 0 2 2 2 1 KaiC RNA12 PF10443.9 PSC70355.1 - 0.13 11.0 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 RNA12 protein DPBB_1 PF03330.18 PSC70356.1 - 1.5e-09 38.0 0.1 2.6e-09 37.2 0.1 1.4 1 0 0 1 1 1 1 Lytic transglycolase Aminotran_1_2 PF00155.21 PSC70357.1 - 8.5e-50 169.9 0.0 1e-49 169.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 PSC70357.1 - 7.3e-07 28.8 0.1 1.1e-06 28.3 0.1 1.1 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 PSC70357.1 - 0.004 16.5 0.0 0.0065 15.8 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 PSC70357.1 - 0.038 12.9 0.0 0.061 12.3 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V SHMT PF00464.19 PSC70357.1 - 0.12 11.0 0.0 0.28 9.7 0.0 1.6 1 1 0 1 1 1 0 Serine hydroxymethyltransferase fn3 PF00041.21 PSC70358.1 - 3.7e-15 56.1 0.0 2.7e-08 34.0 0.0 2.2 2 0 0 2 2 2 2 Fibronectin type III domain D5_N PF08706.11 PSC70359.1 - 0.067 13.5 0.6 0.095 13.0 0.6 1.2 1 0 0 1 1 1 0 D5 N terminal like PelG PF16933.5 PSC70359.1 - 0.24 10.2 1.2 0.32 9.8 1.2 1.1 1 0 0 1 1 1 0 Putative exopolysaccharide Exporter (EPS-E) Peptidase_M16_C PF05193.21 PSC70360.1 - 1.2e-25 90.6 0.0 5.2e-25 88.5 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 PSC70360.1 - 3.6e-06 27.0 0.0 5.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) VEFS-Box PF09733.9 PSC70361.1 - 5e-19 68.5 0.0 9.2e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 VEFS-Box of polycomb protein Transpos_assoc PF13963.6 PSC70361.1 - 0.53 10.6 2.4 0.38 11.1 0.3 1.7 2 0 0 2 2 2 0 Transposase-associated domain BTB_2 PF02214.22 PSC70362.1 - 2.3e-15 56.7 0.0 3.8e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain CENP-N PF05238.13 PSC70362.1 - 0.04 13.2 1.5 0.058 12.7 1.5 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like TFIIA PF03153.13 PSC70362.1 - 0.041 13.9 8.6 0.067 13.2 8.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 PSC70362.1 - 0.32 11.7 8.7 0.9 10.2 8.7 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 PSC70362.1 - 0.63 9.6 15.1 0.98 9.0 15.1 1.2 1 0 0 1 1 1 0 Spt20 family Bromodomain PF00439.25 PSC70363.1 - 3.3e-17 62.3 0.0 5.1e-17 61.7 0.0 1.3 1 1 0 1 1 1 1 Bromodomain FAD_binding_3 PF01494.19 PSC70364.1 - 7.1e-15 55.1 5.0 8.2e-08 31.9 1.5 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 PSC70364.1 - 1e-07 32.1 0.2 1e-07 32.1 0.2 3.4 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 PSC70364.1 - 2.3e-06 26.9 0.0 3.4e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 PSC70364.1 - 7.5e-05 22.1 0.1 0.00015 21.1 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PSC70364.1 - 0.00011 21.1 0.2 0.00016 20.5 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 PSC70364.1 - 0.0002 21.1 5.3 0.0017 18.0 0.1 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 PSC70364.1 - 0.002 17.4 0.6 0.0048 16.2 0.1 1.8 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 PSC70364.1 - 0.0027 16.6 0.2 0.24 10.2 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Glu_dehyd_C PF16912.5 PSC70364.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Pyr_redox PF00070.27 PSC70364.1 - 0.02 15.4 0.0 0.06 13.9 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 PSC70364.1 - 0.029 13.4 2.3 1.1 8.2 0.3 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 PSC70364.1 - 0.044 13.1 1.3 0.14 11.4 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 PSC70364.1 - 0.046 13.0 0.3 0.1 11.9 0.3 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 PSC70364.1 - 0.19 10.8 0.2 0.24 10.5 0.2 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 PSC70365.1 - 7.8e-15 55.0 5.1 8.3e-08 31.9 1.5 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 PSC70365.1 - 1e-07 32.1 0.2 1e-07 32.1 0.2 3.4 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 PSC70365.1 - 2.3e-06 26.9 0.0 3.4e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Squalene epoxidase Pyr_redox_2 PF07992.14 PSC70365.1 - 7e-05 22.2 0.1 0.00014 21.2 0.1 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PSC70365.1 - 0.00011 21.1 0.2 0.00016 20.5 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 PSC70365.1 - 0.0002 21.1 5.3 0.0018 18.0 0.1 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase Thi4 PF01946.17 PSC70365.1 - 0.0021 17.4 0.6 0.0048 16.2 0.1 1.8 2 0 0 2 2 2 1 Thi4 family Trp_halogenase PF04820.14 PSC70365.1 - 0.0028 16.6 0.2 0.24 10.2 0.0 2.2 2 0 0 2 2 2 1 Tryptophan halogenase Glu_dehyd_C PF16912.5 PSC70365.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Glucose dehydrogenase C-terminus Pyr_redox PF00070.27 PSC70365.1 - 0.02 15.4 0.0 0.061 13.9 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 PSC70365.1 - 0.029 13.4 2.3 1.1 8.2 0.3 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 PSC70365.1 - 0.044 13.1 1.3 0.15 11.4 0.1 2.1 2 0 0 2 2 2 0 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 PSC70365.1 - 0.046 13.0 0.3 0.1 11.9 0.3 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GIDA PF01134.22 PSC70365.1 - 0.19 10.7 0.1 0.28 10.2 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF1525 PF07511.11 PSC70366.1 - 0.022 14.9 5.7 0.022 14.9 5.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) TSC22 PF01166.18 PSC70366.1 - 0.46 10.8 5.9 0.83 10.0 5.9 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family TFIIA PF03153.13 PSC70366.1 - 1.2 9.0 13.1 1.7 8.5 13.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ribosomal_S5_C PF03719.15 PSC70367.1 - 1.8e-25 88.2 0.4 3.8e-25 87.1 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Ribosomal_S5 PF00333.20 PSC70367.1 - 4.9e-24 84.1 5.5 1.1e-23 83.0 5.5 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Pkinase PF00069.25 PSC70368.1 - 0.00047 19.6 0.0 0.0042 16.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC70368.1 - 0.0057 16.0 0.0 0.0096 15.2 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Abhydro_lipase PF04083.16 PSC70369.1 - 4.9e-20 70.9 0.0 1.5e-19 69.3 0.0 1.9 1 1 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 PSC70369.1 - 6.8e-18 65.2 0.1 9.5e-18 64.8 0.1 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC70369.1 - 5e-08 32.5 0.0 3.4e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Herpes_capsid PF06112.11 PSC70369.1 - 7.3 6.6 12.1 1.8e+02 2.1 15.1 1.8 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein MFS_1 PF07690.16 PSC70370.1 - 5.5e-52 176.8 44.4 1.7e-49 168.6 28.5 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-PARP PF00645.18 PSC70370.1 - 1.2e-18 67.8 0.0 1.2e-18 67.8 0.0 1.8 2 0 0 2 2 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region Sugar_tr PF00083.24 PSC70370.1 - 6.8e-08 31.8 7.3 6.8e-08 31.8 7.3 3.2 3 1 1 4 4 3 1 Sugar (and other) transporter SDA1 PF05285.12 PSC70370.1 - 0.002 17.6 17.9 0.0027 17.2 17.9 1.1 1 0 0 1 1 1 1 SDA1 CPSF100_C PF13299.6 PSC70370.1 - 0.0057 16.9 5.6 0.0095 16.1 5.6 1.4 1 0 0 1 1 1 1 Cleavage and polyadenylation factor 2 C-terminal Coilin_N PF15862.5 PSC70370.1 - 0.013 15.3 8.2 0.021 14.6 8.2 1.3 1 0 0 1 1 1 0 Coilin N-terminus BUD22 PF09073.10 PSC70370.1 - 0.013 14.8 25.2 0.019 14.3 25.2 1.1 1 0 0 1 1 1 0 BUD22 Mpp10 PF04006.12 PSC70370.1 - 0.023 13.2 19.9 0.035 12.5 19.9 1.2 1 0 0 1 1 1 0 Mpp10 protein DUF2052 PF09747.9 PSC70370.1 - 0.046 13.9 20.5 0.075 13.2 20.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CDC27 PF09507.10 PSC70370.1 - 0.08 12.3 17.5 0.12 11.8 17.5 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CDC45 PF02724.14 PSC70370.1 - 0.085 11.1 20.1 0.12 10.7 20.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 PSC70370.1 - 0.092 12.0 1.8 0.25 10.5 1.8 1.8 1 0 0 1 1 1 0 ZIP Zinc transporter RR_TM4-6 PF06459.12 PSC70370.1 - 0.5 10.1 17.0 0.81 9.5 17.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SpoIIP PF07454.11 PSC70370.1 - 0.76 9.2 10.0 1.1 8.7 10.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DDHD PF02862.17 PSC70370.1 - 1.1 9.4 2.8 1.6 8.9 2.8 1.2 1 0 0 1 1 1 0 DDHD domain Nop53 PF07767.11 PSC70370.1 - 1.3 8.3 21.6 2.1 7.6 21.6 1.3 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Presenilin PF01080.17 PSC70370.1 - 1.6 7.4 10.5 2.7 6.7 10.5 1.3 1 0 0 1 1 1 0 Presenilin CobT PF06213.12 PSC70370.1 - 1.9 7.8 24.5 3.3 7.0 24.5 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SLC12 PF03522.15 PSC70370.1 - 3 6.8 3.5 4 6.4 3.5 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Usp PF00582.26 PSC70370.1 - 3.4 8.2 8.7 8.3 6.9 8.7 1.6 1 0 0 1 1 1 0 Universal stress protein family Eapp_C PF10238.9 PSC70370.1 - 3.8 7.6 6.6 6.8 6.8 6.6 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein RNA_polI_A34 PF08208.11 PSC70370.1 - 4 7.5 25.0 6.9 6.7 25.0 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 DNA_pol_phi PF04931.13 PSC70370.1 - 4.9 5.1 29.1 6.7 4.7 29.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi Rtf2 PF04641.12 PSC70370.1 - 5 6.4 10.7 7.4 5.8 10.7 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger NPR3 PF03666.13 PSC70370.1 - 5.4 5.7 10.0 7.5 5.2 10.0 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 SAPS PF04499.15 PSC70370.1 - 6.2 5.5 10.1 8.7 5.0 10.1 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein XAP5 PF04921.14 PSC70370.1 - 6.9 6.4 13.2 11 5.8 13.2 1.2 1 0 0 1 1 1 0 XAP5, circadian clock regulator TRAP_alpha PF03896.16 PSC70370.1 - 7.6 5.6 12.7 13 4.9 12.7 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit PPL5 PF18168.1 PSC70370.1 - 9.2 5.5 9.3 14 4.9 9.3 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Tab2_like PF06485.11 PSC70371.1 - 1.9e-88 296.4 0.0 2.5e-88 296.1 0.0 1.1 1 0 0 1 1 1 1 RNA-binding protein Tab2/Atab2 RRM_1 PF00076.22 PSC70371.1 - 6.6e-08 32.3 0.0 1.8e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PSC70371.1 - 0.00021 21.1 0.0 0.00041 20.1 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif DUF4614 PF15391.6 PSC70371.1 - 0.013 15.5 1.4 0.013 15.5 1.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) Apt1 PF10351.9 PSC70371.1 - 0.026 13.4 1.2 0.043 12.7 1.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain WD40 PF00400.32 PSC70372.1 - 1.3e-31 108.1 23.9 6.8e-08 33.1 0.2 7.4 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC70372.1 - 6.4e-08 32.8 0.0 0.0082 16.4 0.0 4.9 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Bromodomain PF00439.25 PSC70372.1 - 1.8e-06 28.0 0.0 3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain Ge1_WD40 PF16529.5 PSC70372.1 - 0.00083 18.4 0.0 0.5 9.3 0.0 3.8 4 1 1 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Ribosomal_L3 PF00297.22 PSC70373.1 - 1.1e-175 584.0 16.1 3.3e-174 579.1 16.1 2.0 1 1 0 1 1 1 1 Ribosomal protein L3 Ribosomal_L3 PF00297.22 PSC70374.1 - 2.6e-179 596.0 12.6 2.9e-179 595.8 12.6 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 DUF1336 PF07059.12 PSC70375.1 - 1.4e-55 188.9 0.0 2e-55 188.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1336) START PF01852.19 PSC70375.1 - 1.5e-14 53.9 0.0 3.1e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 START domain TAT_signal PF10518.9 PSC70376.1 - 0.012 15.4 6.5 0.012 15.4 6.5 2.1 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence PsbQ PF05757.11 PSC70376.1 - 0.11 12.2 1.1 0.14 11.9 1.1 1.2 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Ammonium_transp PF00909.21 PSC70377.1 - 1.4e-79 267.7 32.2 7.2e-62 209.3 26.7 2.0 2 0 0 2 2 2 2 Ammonium Transporter Family Ammonium_transp PF00909.21 PSC70378.1 - 8.2e-72 242.1 29.4 1.9e-71 240.9 29.4 1.5 1 1 0 1 1 1 1 Ammonium Transporter Family Ribo_biogen_C PF04034.13 PSC70379.1 - 5.8e-49 165.0 0.0 8.7e-49 164.5 0.0 1.3 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 PSC70379.1 - 9.1e-11 41.4 0.6 1.5e-10 40.7 0.0 1.7 2 0 0 2 2 2 1 Possible Fer4-like domain in RNase L inhibitor, RLI RRM_1 PF00076.22 PSC70379.1 - 7e-08 32.2 0.0 1.3e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PsbW PF07123.12 PSC70379.1 - 9.1 6.3 6.2 12 5.9 4.7 1.9 2 0 0 2 2 2 0 Photosystem II reaction centre W protein (PsbW) ShK PF01549.24 PSC70380.1 - 0.033 14.7 7.0 0.033 14.7 7.0 3.8 4 0 0 4 4 4 0 ShK domain-like DUF155 PF02582.14 PSC70381.1 - 3.6e-22 79.3 0.2 5.6e-22 78.7 0.2 1.3 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Adenylsucc_synt PF00709.21 PSC70382.1 - 8.9e-173 575.0 0.0 1e-172 574.8 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Pkinase PF00069.25 PSC70383.1 - 1e-78 264.3 0.0 1.5e-78 263.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC70383.1 - 9.2e-42 143.1 0.0 1.5e-41 142.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 PSC70383.1 - 2.1e-13 49.8 0.0 4.7e-13 48.7 0.0 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 PSC70383.1 - 3.5e-08 33.1 0.0 5.1e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like AdenylateSensor PF16579.5 PSC70383.1 - 6.3e-05 23.4 0.1 0.0017 18.8 0.0 2.7 3 0 0 3 3 3 1 Adenylate sensor of SNF1-like protein kinase RIO1 PF01163.22 PSC70383.1 - 0.00024 20.8 1.9 0.00043 19.9 1.9 1.3 1 0 0 1 1 1 1 RIO1 family Haspin_kinase PF12330.8 PSC70383.1 - 0.054 12.4 0.2 0.081 11.9 0.2 1.3 1 0 0 1 1 1 0 Haspin like kinase domain YukC PF10140.9 PSC70383.1 - 0.076 11.8 0.2 0.17 10.7 0.2 1.5 1 1 1 2 2 2 0 WXG100 protein secretion system (Wss), protein YukC UBA_2 PF08587.11 PSC70383.1 - 0.1 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Pox_ser-thr_kin PF05445.11 PSC70383.1 - 0.11 11.5 1.0 1.1 8.2 0.1 2.0 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase Aldedh PF00171.22 PSC70384.1 - 4.4e-138 460.6 0.1 5e-138 460.5 0.1 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 PSC70384.1 - 0.025 13.6 0.0 0.036 13.1 0.0 1.1 1 0 0 1 1 1 0 Acyl-CoA reductase (LuxC) Epimerase PF01370.21 PSC70385.1 - 3.4e-07 30.0 0.0 6.2e-07 29.1 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PSC70385.1 - 0.0032 16.9 0.0 0.017 14.5 0.0 1.9 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase UDPG_MGDP_dh_N PF03721.14 PSC70385.1 - 0.0078 15.8 0.0 0.017 14.7 0.0 1.4 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 PSC70385.1 - 0.012 15.9 0.0 0.02 15.1 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.15 PSC70385.1 - 0.067 13.3 0.0 0.11 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase cpYpsA PF12694.7 PSC70385.1 - 0.15 11.8 0.6 0.49 10.2 0.3 1.9 2 0 0 2 2 2 0 Circularly permutated YpsA SLOG family PAC2 PF09754.9 PSC70386.1 - 0.059 13.4 0.0 0.079 12.9 0.0 1.2 1 0 0 1 1 1 0 PAC2 family FAD_binding_7 PF03441.14 PSC70387.1 - 1.7e-55 187.7 0.0 2.6e-55 187.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 PSC70387.1 - 6e-37 127.2 0.0 1.2e-36 126.2 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase rve PF00665.26 PSC70387.1 - 2.9e-18 66.2 0.0 6e-18 65.2 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain SH3_15 PF18346.1 PSC70387.1 - 0.0088 16.3 0.4 15 6.0 0.0 3.7 3 0 0 3 3 3 2 Mind bomb SH3 repeat domain rve_3 PF13683.6 PSC70387.1 - 0.021 14.6 0.0 0.052 13.3 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain V-ATPase_G PF03179.15 PSC70388.1 - 4.1e-28 98.0 12.2 4.5e-28 97.9 12.2 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit ApoLp-III PF07464.11 PSC70388.1 - 0.0023 18.0 5.7 0.0036 17.4 5.7 1.3 1 0 0 1 1 1 1 Apolipophorin-III precursor (apoLp-III) Gluconate_2-dh3 PF13618.6 PSC70388.1 - 0.062 13.5 2.4 0.075 13.3 2.4 1.1 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 vATP-synt_E PF01991.18 PSC70388.1 - 0.088 12.2 9.0 0.11 11.9 9.0 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit OmpH PF03938.14 PSC70388.1 - 0.16 12.3 9.5 0.18 12.1 9.5 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) HrpE PF06188.12 PSC70388.1 - 0.35 10.7 6.0 0.42 10.5 6.0 1.1 1 0 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E ATP-synt_B PF00430.18 PSC70388.1 - 1.8 8.7 17.4 5.4 7.1 16.5 1.9 1 1 0 1 1 1 0 ATP synthase B/B' CF(0) Methyltransf_16 PF10294.9 PSC70389.1 - 4.7e-28 98.1 0.0 2e-27 96.0 0.0 1.8 1 1 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 PSC70389.1 - 0.014 15.2 0.0 0.021 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain LSM PF01423.22 PSC70391.1 - 1.2e-20 72.9 0.0 1.4e-20 72.7 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 PSC70391.1 - 0.16 12.2 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 RimP C-terminal SH3 domain Peptidase_M1 PF01433.20 PSC70392.1 - 1.6e-47 161.9 0.0 2.4e-47 161.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 PSC70392.1 - 2.1e-36 124.4 0.0 3.6e-36 123.7 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 PSC70392.1 - 2.9e-19 70.0 0.0 5.2e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Pectate_lyase_3 PF12708.7 PSC70392.1 - 0.083 12.7 3.0 0.086 12.7 0.3 2.1 2 0 0 2 2 2 0 Pectate lyase superfamily protein LEA_2 PF03168.13 PSC70392.1 - 0.1 13.2 0.1 1.8 9.1 0.0 2.7 3 0 0 3 3 3 0 Late embryogenesis abundant protein Peptidase_M61 PF05299.12 PSC70392.1 - 4 7.9 4.9 11 6.5 2.1 2.7 2 1 0 2 2 2 0 M61 glycyl aminopeptidase Peptidase_M1 PF01433.20 PSC70393.1 - 2.4e-44 151.5 0.0 4.1e-44 150.8 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 PSC70393.1 - 2.2e-36 124.4 0.0 3.7e-36 123.6 0.0 1.4 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 PSC70393.1 - 3e-19 69.9 0.0 5.3e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Pectate_lyase_3 PF12708.7 PSC70393.1 - 0.087 12.7 3.0 0.088 12.6 0.3 2.1 2 0 0 2 2 2 0 Pectate lyase superfamily protein LEA_2 PF03168.13 PSC70393.1 - 0.11 13.1 0.0 1.8 9.1 0.0 2.7 3 0 0 3 3 3 0 Late embryogenesis abundant protein AhpC-TSA PF00578.21 PSC70394.1 - 4.7e-19 68.5 0.0 7.7e-19 67.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PSC70394.1 - 1.2e-16 60.8 0.0 1.6e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 PSC70394.1 - 0.0012 19.1 0.0 0.0022 18.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 PSC70394.1 - 0.0021 18.0 0.1 0.035 14.1 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin Palm_thioest PF02089.15 PSC70395.1 - 2.9e-70 236.9 0.0 3.5e-70 236.6 0.0 1.1 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DCAF15_WD40 PF14939.6 PSC70395.1 - 0.2 11.3 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat Myb_DNA-binding PF00249.31 PSC70396.1 - 8.6e-06 25.8 0.0 1.5e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain SUIM_assoc PF16619.5 PSC70396.1 - 1.5 9.0 6.5 1.6 8.9 1.9 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 PsbP PF01789.16 PSC70397.1 - 3.5e-42 144.2 1.6 4.2e-42 143.9 1.6 1.1 1 0 0 1 1 1 1 PsbP GTP_EFTU PF00009.27 PSC70398.1 - 4.7e-61 205.7 0.0 8e-61 205.0 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 PSC70398.1 - 1.7e-33 115.0 0.0 5.1e-33 113.4 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 PSC70398.1 - 8.6e-20 70.6 0.0 2.1e-19 69.3 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 PSC70398.1 - 4.7e-15 55.4 0.2 2.2e-14 53.3 0.0 2.1 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 PSC70398.1 - 6.9e-11 42.4 0.0 1.4e-10 41.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PSC70398.1 - 0.016 15.3 0.1 0.033 14.3 0.1 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Aminotran_5 PF00266.19 PSC70399.1 - 3e-58 197.6 0.4 3.6e-58 197.3 0.4 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 PSC70399.1 - 0.0043 16.4 0.4 0.0078 15.6 0.4 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 PSC70399.1 - 0.01 15.2 0.2 0.016 14.5 0.2 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase Aminotran_5 PF00266.19 PSC70400.1 - 3e-58 197.6 0.4 3.6e-58 197.3 0.4 1.1 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 PSC70400.1 - 0.0043 16.4 0.4 0.0078 15.6 0.4 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 PSC70400.1 - 0.01 15.2 0.2 0.016 14.5 0.2 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase ENTH PF01417.20 PSC70401.1 - 1.3e-34 118.9 0.0 2.2e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 PSC70401.1 - 2.3e-05 23.5 0.0 3e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 ANTH domain COMM_domain PF07258.14 PSC70401.1 - 0.18 12.0 0.3 0.34 11.0 0.0 1.6 2 0 0 2 2 2 0 COMM domain ENTH PF01417.20 PSC70402.1 - 1.3e-34 118.9 0.0 2.2e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 PSC70402.1 - 2.3e-05 23.5 0.0 3e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 ANTH domain COMM_domain PF07258.14 PSC70402.1 - 0.18 12.0 0.3 0.34 11.0 0.0 1.6 2 0 0 2 2 2 0 COMM domain ENTH PF01417.20 PSC70403.1 - 1.3e-34 118.9 0.0 2.2e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 PSC70403.1 - 2.3e-05 23.5 0.0 3e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 ANTH domain COMM_domain PF07258.14 PSC70403.1 - 0.18 12.0 0.3 0.34 11.0 0.0 1.6 2 0 0 2 2 2 0 COMM domain MCM_lid PF17855.1 PSC70404.1 - 9.4e-05 22.8 0.9 0.00019 21.8 0.9 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 PSC70404.1 - 0.0049 16.7 0.0 0.008 16.0 0.0 1.3 1 0 0 1 1 1 1 MCM OB domain HSP70 PF00012.20 PSC70405.1 - 1.7e-238 792.7 0.0 1.9e-238 792.6 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PSC70405.1 - 1.7e-14 53.4 0.0 5.9e-13 48.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein HSP70 PF00012.20 PSC70406.1 - 1.8e-238 792.6 0.0 2.1e-238 792.4 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PSC70406.1 - 1.8e-14 53.3 0.0 6.2e-13 48.3 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Forkhead_N PF08430.12 PSC70406.1 - 1.1 9.9 31.7 2.9 8.5 31.7 1.7 1 0 0 1 1 1 0 Forkhead N-terminal region FSH1 PF03959.13 PSC70407.1 - 4e-42 144.3 0.0 9.6e-29 100.6 0.0 2.2 2 0 0 2 2 2 2 Serine hydrolase (FSH1) Rhodanese_C PF12368.8 PSC70407.1 - 1.8e-10 41.0 6.8 1.8e-10 41.0 6.8 2.7 3 1 1 4 4 4 1 Rhodanase C-terminal UPF0176_N PF17773.1 PSC70407.1 - 1.5e-08 34.9 0.0 3.2e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 UPF0176 acylphosphatase like domain SLATT_1 PF18181.1 PSC70407.1 - 0.16 11.9 0.1 0.16 11.9 0.1 3.5 4 0 0 4 4 4 0 SMODS and SLOG-associating 2TM effector domain 1 rve PF00665.26 PSC70408.1 - 1.6e-17 63.8 0.0 3.5e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain GST_N PF02798.20 PSC70408.1 - 1.1e-07 32.0 0.0 2.8e-07 30.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain rve_3 PF13683.6 PSC70408.1 - 0.0091 15.8 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain GST_C_3 PF14497.6 PSC70408.1 - 0.015 15.5 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PSC70408.1 - 0.11 12.9 0.0 0.26 11.7 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 PSC70408.1 - 0.18 12.1 0.0 0.45 10.8 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PsbP PF01789.16 PSC70409.1 - 1e-10 42.0 0.0 2.2e-10 40.9 0.0 1.6 1 1 0 1 1 1 1 PsbP PsbQ PF05757.11 PSC70409.1 - 0.0037 17.0 5.5 0.0051 16.6 2.5 2.2 2 0 0 2 2 2 1 Oxygen evolving enhancer protein 3 (PsbQ) Rhodanese PF00581.20 PSC70410.1 - 2.4e-05 24.8 0.0 4.4e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Kelch_1 PF01344.25 PSC70411.1 - 7e-33 112.0 17.7 1.7e-11 43.5 0.0 7.7 7 1 0 7 7 7 5 Kelch motif Dev_Cell_Death PF10539.9 PSC70411.1 - 3e-32 111.2 0.0 5.2e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Development and cell death domain Kelch_6 PF13964.6 PSC70411.1 - 2.5e-23 81.5 8.6 1.6e-06 28.2 0.0 7.9 3 2 4 7 7 7 4 Kelch motif MMS1_N PF10433.9 PSC70411.1 - 1.5e-14 53.5 0.0 2.4e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Kelch_2 PF07646.15 PSC70411.1 - 4.4e-10 39.1 1.2 0.12 12.4 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 PSC70411.1 - 6.9e-06 25.9 6.3 0.0071 16.3 0.0 4.0 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 PSC70411.1 - 0.0013 18.7 11.2 0.58 10.2 0.8 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 PSC70411.1 - 0.0049 17.1 8.3 2.3 8.6 1.5 5.5 4 0 0 4 4 4 1 Galactose oxidase, central domain CPSF_A PF03178.15 PSC70411.1 - 0.017 14.5 0.0 2.4 7.4 0.0 2.4 2 0 0 2 2 2 0 CPSF A subunit region DUF4201 PF13870.6 PSC70411.1 - 0.47 10.2 5.5 0.78 9.4 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Ran-binding PF05508.11 PSC70411.1 - 1.2 8.0 3.0 1.9 7.4 3.0 1.2 1 0 0 1 1 1 0 RanGTP-binding protein Kelch_1 PF01344.25 PSC70412.1 - 3.9e-39 132.0 14.5 1.7e-11 43.5 0.0 7.3 7 0 0 7 7 7 6 Kelch motif Dev_Cell_Death PF10539.9 PSC70412.1 - 3e-32 111.2 0.0 5.2e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Development and cell death domain Kelch_6 PF13964.6 PSC70412.1 - 4.7e-29 99.7 5.0 1.6e-06 28.2 0.0 7.8 3 2 4 7 7 7 5 Kelch motif MMS1_N PF10433.9 PSC70412.1 - 1.5e-14 53.5 0.0 2.3e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Kelch_2 PF07646.15 PSC70412.1 - 2.2e-11 43.2 1.0 0.12 12.4 0.0 6.3 7 0 0 7 7 7 3 Kelch motif Kelch_5 PF13854.6 PSC70412.1 - 1.2e-06 28.3 4.4 0.0071 16.3 0.0 4.2 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 PSC70412.1 - 0.0011 18.9 11.2 0.58 10.2 0.8 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 PSC70412.1 - 0.0014 18.9 9.3 2.2 8.6 1.5 6.2 5 0 0 5 5 5 1 Galactose oxidase, central domain CPSF_A PF03178.15 PSC70412.1 - 0.016 14.5 0.0 2.4 7.4 0.0 2.4 2 0 0 2 2 2 0 CPSF A subunit region DUF4201 PF13870.6 PSC70412.1 - 0.47 10.2 5.5 0.78 9.5 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Ran-binding PF05508.11 PSC70412.1 - 1.2 8.0 3.0 1.9 7.4 3.0 1.2 1 0 0 1 1 1 0 RanGTP-binding protein Kelch_1 PF01344.25 PSC70413.1 - 7e-33 112.0 17.7 1.7e-11 43.5 0.0 7.7 7 1 0 7 7 7 5 Kelch motif Dev_Cell_Death PF10539.9 PSC70413.1 - 3e-32 111.2 0.0 5.2e-32 110.4 0.0 1.4 1 0 0 1 1 1 1 Development and cell death domain Kelch_6 PF13964.6 PSC70413.1 - 2.5e-23 81.5 8.6 1.6e-06 28.2 0.0 7.9 3 2 4 7 7 7 4 Kelch motif MMS1_N PF10433.9 PSC70413.1 - 1.5e-14 53.5 0.0 2.4e-10 39.7 0.0 2.2 2 0 0 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Kelch_2 PF07646.15 PSC70413.1 - 4.4e-10 39.1 1.2 0.12 12.4 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.6 PSC70413.1 - 6.9e-06 25.9 6.3 0.0071 16.3 0.0 4.0 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 PSC70413.1 - 0.0013 18.7 11.2 0.58 10.2 0.8 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 PSC70413.1 - 0.0048 17.2 8.3 2.3 8.6 1.5 5.5 4 0 0 4 4 4 1 Galactose oxidase, central domain CPSF_A PF03178.15 PSC70413.1 - 0.017 14.5 0.0 2.4 7.4 0.0 2.4 2 0 0 2 2 2 0 CPSF A subunit region DUF4201 PF13870.6 PSC70413.1 - 0.47 10.2 5.5 0.78 9.4 5.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Ran-binding PF05508.11 PSC70413.1 - 1.2 8.0 3.0 1.9 7.4 3.0 1.2 1 0 0 1 1 1 0 RanGTP-binding protein PhosphMutase PF10143.9 PSC70414.1 - 1.1e-51 175.2 0.0 2e-51 174.3 0.0 1.5 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 PSC70414.1 - 9.8e-26 90.6 0.0 1.3e-25 90.2 0.0 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 PSC70414.1 - 7e-05 22.6 0.0 0.00011 21.9 0.0 1.4 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Pex14_N PF04695.13 PSC70414.1 - 0.62 10.7 14.8 1.1 9.9 14.8 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 PSC70414.1 - 2 8.3 18.0 2.9 7.8 18.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 PSC70414.1 - 7 6.5 6.9 12 5.8 6.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) MatE PF01554.18 PSC70415.1 - 1.5e-41 141.8 18.1 7.4e-25 87.5 4.2 2.2 2 0 0 2 2 2 2 MatE 7TM-7TMR_HD PF07698.11 PSC70415.1 - 0.12 12.1 0.2 0.12 12.1 0.2 2.6 2 1 0 2 2 2 0 7TM receptor with intracellular HD hydrolase Pkinase PF00069.25 PSC70416.1 - 2.8e-72 243.3 0.0 3.5e-72 242.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC70416.1 - 5.3e-33 114.4 0.0 8.3e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_6 PF13516.6 PSC70416.1 - 8.8e-06 25.4 0.0 0.076 13.1 0.0 3.7 3 0 0 3 3 3 2 Leucine Rich repeat Kdo PF06293.14 PSC70416.1 - 5.7e-05 22.6 0.2 9.9e-05 21.8 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PSC70416.1 - 0.0092 15.0 0.1 0.014 14.4 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 PSC70416.1 - 0.043 13.1 0.0 0.43 9.8 0.0 2.1 1 1 1 2 2 2 0 Kinase-like FTA2 PF13095.6 PSC70416.1 - 0.23 11.1 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 PSC70416.1 - 0.58 10.0 0.0 0.58 10.0 0.0 3.7 4 1 1 5 5 5 0 Phosphotransferase enzyme family Pentapeptide PF00805.22 PSC70417.1 - 4.1e-17 61.5 3.2 5.4e-06 25.9 0.8 4.2 2 1 1 4 4 4 4 Pentapeptide repeats (8 copies) zf-MYND PF01753.18 PSC70417.1 - 7.1e-10 38.8 7.8 7.1e-10 38.8 7.8 2.3 2 0 0 2 2 2 1 MYND finger Pentapeptide_4 PF13599.6 PSC70417.1 - 1e-08 35.2 0.0 0.00029 20.9 0.0 2.3 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 PSC70417.1 - 6.5e-08 32.6 0.6 0.00054 20.1 1.2 3.0 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) zf-Mss51 PF13824.6 PSC70417.1 - 0.00083 19.4 0.8 0.0023 18.0 0.8 1.6 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-C6H2 PF15801.5 PSC70417.1 - 0.12 12.7 3.2 0.3 11.4 3.2 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding Pkinase_Tyr PF07714.17 PSC70418.1 - 4.1e-32 111.5 0.0 2e-31 109.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC70418.1 - 1.8e-30 106.2 0.0 9.6e-30 103.8 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain GAF PF01590.26 PSC70418.1 - 0.00013 22.6 0.0 0.00013 22.6 0.0 2.6 3 0 0 3 3 3 1 GAF domain Pkinase_fungal PF17667.1 PSC70418.1 - 0.0039 16.0 2.1 0.28 9.9 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase GAF_2 PF13185.6 PSC70418.1 - 0.035 14.4 0.1 0.18 12.1 0.0 2.2 2 0 0 2 2 2 0 GAF domain TFIIA PF03153.13 PSC70418.1 - 0.89 9.5 31.6 1.6 8.6 31.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 PSC70418.1 - 2.6 6.7 14.4 3.8 6.2 14.4 1.2 1 0 0 1 1 1 0 Presenilin PAT1 PF09770.9 PSC70418.1 - 3.9 5.6 24.2 5.4 5.2 24.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.13 PSC70418.1 - 5.3 6.8 13.7 37 4.0 12.8 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain MMR1 PF08505.10 PSC70418.1 - 6.9 6.9 18.6 11 6.2 18.6 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein GST_C_3 PF14497.6 PSC70419.1 - 1.2e-13 51.1 0.0 2.1e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PSC70419.1 - 2.5e-06 27.6 0.0 4e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PSC70419.1 - 0.00026 21.3 0.0 0.00058 20.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PSC70419.1 - 0.025 14.6 0.1 0.05 13.6 0.1 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tweety PF04906.13 PSC70420.1 - 0.01 14.6 5.7 0.019 13.7 5.7 1.4 1 0 0 1 1 1 1 Tweety TPR_1 PF00515.28 PSC70420.1 - 0.13 12.1 7.4 1.3 9.0 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 PSC70420.1 - 2.4 8.5 9.5 1.5 9.1 0.9 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 PSC70420.1 - 2.5 8.9 8.6 4.1 8.3 0.2 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Herpes_pp85 PF04637.12 PSC70420.1 - 3.8 5.8 5.8 6.1 5.1 5.8 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) Tweety PF04906.13 PSC70421.1 - 0.009 14.7 5.6 0.017 13.8 5.6 1.4 1 0 0 1 1 1 1 Tweety TPR_1 PF00515.28 PSC70421.1 - 0.11 12.4 7.4 1.2 9.0 0.3 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 PSC70421.1 - 2 8.8 9.5 1.5 9.2 0.9 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 PSC70421.1 - 2.4 9.0 8.9 3.8 8.3 0.2 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat Herpes_pp85 PF04637.12 PSC70421.1 - 3.5 5.9 5.8 5.8 5.2 5.8 1.2 1 0 0 1 1 1 0 Herpesvirus phosphoprotein 85 (HHV6-7 U14/HCMV UL25) YL1 PF05764.13 PSC70422.1 - 2.9e-29 102.9 12.8 2.9e-29 102.9 12.8 2.2 2 0 0 2 2 2 1 YL1 nuclear protein YL1_C PF08265.11 PSC70422.1 - 6.3e-15 54.6 0.6 9.6e-15 54.0 0.0 1.6 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain zf-HIT PF04438.16 PSC70422.1 - 0.25 11.3 0.0 0.39 10.6 0.0 1.2 1 0 0 1 1 1 0 HIT zinc finger AFG1_ATPase PF03969.16 PSC70423.1 - 6.3e-63 212.9 0.0 2.5e-27 95.7 0.0 4.5 5 0 0 5 5 5 4 AFG1-like ATPase AAA_16 PF13191.6 PSC70423.1 - 0.0034 17.8 6.2 0.0034 17.8 6.2 3.2 2 2 1 3 3 3 1 AAA ATPase domain ABC_tran PF00005.27 PSC70423.1 - 0.0078 16.7 0.0 0.03 14.8 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 PSC70423.1 - 0.15 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Glyco_hydro_31 PF01055.26 PSC70424.1 - 2.5e-145 485.0 0.0 3.1e-145 484.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 PSC70424.1 - 1.6e-17 63.7 0.0 2.8e-17 63.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Trefoil PF00088.18 PSC70424.1 - 1.3e-09 37.8 4.7 1.3e-09 37.8 4.7 1.8 2 0 0 2 2 2 1 Trefoil (P-type) domain Thioredox_DsbH PF03190.15 PSC70425.1 - 2.9e-37 128.1 0.5 1.2e-36 126.1 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 PSC70425.1 - 9.8e-10 38.5 0.0 9.8e-10 38.5 0.0 2.3 3 0 0 3 3 3 1 Thioredoxin-like U-box PF04564.15 PSC70425.1 - 7.2e-07 29.3 0.0 1.6e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 U-box domain BAG PF02179.16 PSC70425.1 - 0.077 13.4 1.3 0.19 12.2 0.6 2.1 2 0 0 2 2 2 0 BAG domain Glyco_hydro_88 PF07470.13 PSC70425.1 - 0.11 11.6 0.2 5.1 6.1 0.0 2.3 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 NYD-SP28 PF14772.6 PSC70425.1 - 0.11 12.5 2.2 0.16 12.0 0.3 2.3 2 0 0 2 2 2 0 Sperm tail UPF0184 PF03670.13 PSC70425.1 - 0.43 11.0 1.6 1.4 9.4 0.1 2.5 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) Thioredox_DsbH PF03190.15 PSC70426.1 - 2.8e-37 128.2 0.5 1.2e-36 126.1 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 PSC70426.1 - 9.7e-10 38.5 0.0 9.7e-10 38.5 0.0 2.3 3 0 0 3 3 3 1 Thioredoxin-like U-box PF04564.15 PSC70426.1 - 7.1e-07 29.3 0.0 1.6e-06 28.2 0.0 1.6 1 0 0 1 1 1 1 U-box domain BAG PF02179.16 PSC70426.1 - 0.077 13.4 1.3 0.18 12.2 0.6 2.0 2 0 0 2 2 2 0 BAG domain Glyco_hydro_88 PF07470.13 PSC70426.1 - 0.11 11.6 0.2 5 6.1 0.0 2.3 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 UPF0184 PF03670.13 PSC70426.1 - 0.42 11.0 1.6 1.4 9.4 0.1 2.5 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0184) CCDC66 PF15236.6 PSC70427.1 - 3.6e-11 43.1 22.8 3.6e-11 43.1 22.8 3.4 3 0 0 3 3 3 1 Coiled-coil domain-containing protein 66 dCMP_cyt_deam_1 PF00383.23 PSC70428.1 - 2.6e-22 78.6 0.4 2.6e-22 78.6 0.4 2.1 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 PSC70428.1 - 4.8e-09 36.1 0.0 7.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 MafB19-like deaminase TFIIF_alpha PF05793.12 PSC70430.1 - 8.3e-22 77.5 14.5 4.8e-10 38.6 14.3 2.1 1 1 1 2 2 2 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) XPC-binding PF09280.11 PSC70430.1 - 0.22 11.3 0.8 0.42 10.4 0.1 1.9 2 0 0 2 2 2 0 XPC-binding domain SPAN-X PF07458.12 PSC70430.1 - 0.72 10.3 4.8 3.2 8.2 0.1 2.8 3 0 0 3 3 3 0 Sperm protein associated with nucleus, mapped to X chromosome TFIIF_alpha PF05793.12 PSC70431.1 - 1.4e-21 76.7 15.4 2.7e-19 69.2 15.4 2.1 1 1 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) XPC-binding PF09280.11 PSC70431.1 - 0.21 11.4 0.8 0.41 10.4 0.1 1.9 2 0 0 2 2 2 0 XPC-binding domain SPAN-X PF07458.12 PSC70431.1 - 0.58 10.6 4.6 3.2 8.3 0.1 2.8 3 0 0 3 3 3 0 Sperm protein associated with nucleus, mapped to X chromosome zf-C2H2_2 PF12756.7 PSC70432.1 - 1.6e-18 66.9 0.0 8.5e-17 61.3 0.0 2.3 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) INTAP PF16617.5 PSC70432.1 - 0.041 14.2 1.5 0.076 13.4 1.5 1.5 1 0 0 1 1 1 0 Intersectin and clathrin adaptor AP2 binding region Peptidase_S28 PF05577.12 PSC70433.1 - 5.2e-65 219.9 0.0 7e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 PSC70433.1 - 3.8e-05 23.5 0.0 6.4e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC70433.1 - 0.00019 20.8 0.0 0.00035 19.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S37 PF05576.11 PSC70433.1 - 0.001 17.8 0.0 0.0017 17.1 0.0 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 DUF2920 PF11144.8 PSC70433.1 - 0.11 11.7 0.1 0.22 10.7 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2920) TPR_1 PF00515.28 PSC70434.1 - 1.1e-18 66.2 3.8 1.8e-06 27.5 0.5 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PSC70434.1 - 7.4e-15 53.8 7.7 7.8e-05 22.5 0.9 3.9 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 PSC70434.1 - 1.3e-08 34.4 0.3 0.038 14.2 0.1 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat RPAP3_C PF13877.6 PSC70434.1 - 1.5e-08 35.1 0.0 2.6e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Potential Monad-binding region of RPAP3 TPR_12 PF13424.6 PSC70434.1 - 2.8e-06 27.5 9.0 0.0054 17.0 5.8 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PSC70434.1 - 0.00048 20.1 2.6 1.8 8.7 0.1 3.7 2 1 1 3 3 3 2 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.6 PSC70434.1 - 0.00078 19.1 0.9 0.23 11.2 0.0 3.3 1 1 2 3 3 3 1 TPR repeat TPR_7 PF13176.6 PSC70434.1 - 0.00089 19.1 3.6 0.055 13.5 0.0 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 PSC70434.1 - 0.0046 17.1 21.9 0.008 16.3 5.7 4.2 2 1 2 4 4 4 3 Tetratricopeptide repeat TFIIA PF03153.13 PSC70434.1 - 0.0056 16.7 17.7 0.0056 16.7 17.7 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Lin-8 PF03353.15 PSC70434.1 - 0.0097 15.5 1.5 0.019 14.6 1.5 1.4 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist TPR_14 PF13428.6 PSC70434.1 - 0.024 15.4 0.1 0.024 15.4 0.1 6.2 4 2 3 7 7 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 PSC70434.1 - 0.025 14.5 9.2 3.5 7.6 1.2 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 PSC70434.1 - 0.13 12.7 3.2 24 5.6 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PCM1_C PF15717.5 PSC70434.1 - 1.2 7.7 5.7 1.9 7.1 5.7 1.2 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus Clat_adaptor_s PF01217.20 PSC70435.1 - 3.1e-52 176.3 2.4 4.3e-52 175.8 2.4 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AP2 PF00847.20 PSC70435.1 - 4e-06 27.0 0.1 1.6e-05 25.1 0.1 2.1 1 0 0 1 1 1 1 AP2 domain Rad51 PF08423.11 PSC70435.1 - 0.032 13.5 0.1 0.058 12.7 0.1 1.3 1 0 0 1 1 1 0 Rad51 Ribosomal_L2_C PF03947.18 PSC70436.1 - 3.9e-47 159.6 3.3 1e-46 158.2 3.3 1.7 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 PSC70436.1 - 1.6e-15 56.8 0.1 4.9e-15 55.3 0.1 1.8 2 0 0 2 2 2 1 Ribosomal Proteins L2, RNA binding domain Lipase_3 PF01764.25 PSC70436.1 - 1.2e-05 25.2 0.0 2.4e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 PSC70436.1 - 0.011 15.1 0.0 0.25 10.6 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Occludin_ELL PF07303.13 PSC70437.1 - 1.9e-06 28.5 0.4 3.4e-06 27.7 0.4 1.4 1 0 0 1 1 1 1 Occludin homology domain DUF3223 PF11523.8 PSC70438.1 - 3.5e-19 69.4 0.0 5.8e-19 68.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3223) Ins134_P3_kin PF05770.11 PSC70439.1 - 7.6e-30 103.9 0.0 7.7e-18 64.7 0.0 2.1 2 0 0 2 2 2 2 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain SHS2_Rpb7-N PF03876.17 PSC70440.1 - 8.7e-07 29.2 0.1 1.5e-06 28.5 0.1 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RPA43_OB PF17875.1 PSC70440.1 - 0.0017 19.0 0.0 0.029 15.0 0.0 4.4 2 2 1 3 3 3 2 RPA43 OB domain in RNA Pol I TFIIA PF03153.13 PSC70440.1 - 0.0099 15.9 28.7 0.011 15.7 28.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit PA26 PF04636.13 PSC70440.1 - 0.49 9.3 3.3 0.64 8.9 3.3 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Neur_chan_memb PF02932.16 PSC70440.1 - 1.8 8.6 9.4 2.3 8.2 9.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SOG2 PF10428.9 PSC70440.1 - 1.8 7.7 12.3 2.2 7.4 12.3 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein CDC45 PF02724.14 PSC70440.1 - 2.7 6.2 16.8 3.6 5.8 16.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Plasmodium_Vir PF05795.11 PSC70440.1 - 3.1 7.1 9.7 3.8 6.8 9.7 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein SAPS PF04499.15 PSC70440.1 - 3.9 6.2 8.9 4.5 5.9 8.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Borrelia_P83 PF05262.11 PSC70440.1 - 5.3 5.4 26.9 5.5 5.4 26.9 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein zf-C3HC4_3 PF13920.6 PSC70441.1 - 9.5e-07 28.6 11.4 1.4e-06 28.0 11.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC70441.1 - 2.7e-06 27.1 13.5 4.1e-06 26.6 13.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PSC70441.1 - 5e-06 26.6 12.4 8.6e-06 25.8 12.4 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 PSC70441.1 - 5.5e-05 23.1 6.2 5.5e-05 23.1 6.2 1.6 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.6 PSC70441.1 - 9.6e-05 22.6 13.2 0.00014 22.1 13.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PSC70441.1 - 0.00054 19.7 13.8 0.00084 19.1 13.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 PSC70441.1 - 0.014 15.2 4.7 0.035 14.0 4.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) GH3 PF03321.13 PSC70441.1 - 0.018 13.9 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 GH3 auxin-responsive promoter zf-RING_5 PF14634.6 PSC70441.1 - 0.052 13.5 13.1 0.12 12.3 13.2 1.6 1 1 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 PSC70441.1 - 0.16 11.8 13.5 0.27 11.2 13.5 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 PSC70441.1 - 0.28 11.0 9.7 0.65 9.8 9.7 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 PSC70441.1 - 2.9 8.1 9.6 4.6 7.4 9.6 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF16 PF01519.16 PSC70442.1 - 0.042 14.3 0.1 0.064 13.8 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF16 TALPID3 PF15324.6 PSC70442.1 - 0.12 10.0 0.1 0.16 9.6 0.1 1.1 1 0 0 1 1 1 0 Hedgehog signalling target 5_nucleotid PF05761.14 PSC70445.1 - 6.9e-158 526.3 0.0 8.9e-158 525.9 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.6 PSC70445.1 - 0.028 14.5 0.0 5.4 7.1 0.0 2.9 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase LRRNT_2 PF08263.12 PSC70445.1 - 0.1 12.9 0.2 0.26 11.6 0.2 1.7 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain RWP-RK PF02042.15 PSC70446.1 - 3.1e-16 59.1 0.0 5.7e-16 58.2 0.0 1.4 1 0 0 1 1 1 1 RWP-RK domain Rhodanese PF00581.20 PSC70446.1 - 5e-08 33.4 0.0 1.4e-07 32.0 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain DUF2722 PF10846.8 PSC70446.1 - 0.0008 18.5 5.8 0.0008 18.5 5.8 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) GAF_2 PF13185.6 PSC70446.1 - 0.013 15.8 0.1 0.079 13.3 0.0 2.4 2 0 0 2 2 2 0 GAF domain HTH_28 PF13518.6 PSC70446.1 - 0.015 15.4 0.0 0.061 13.5 0.0 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4050 PF13259.6 PSC70446.1 - 0.43 10.9 3.5 2.5 8.4 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4050) DUF4820 PF16091.5 PSC70446.1 - 0.44 9.9 7.4 2.1 7.7 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF1764 PF08576.10 PSC70446.1 - 1.3 10.0 9.0 2.9 8.8 0.4 2.3 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) CPSF100_C PF13299.6 PSC70446.1 - 2.1 8.5 11.4 2 8.6 1.1 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal FHIPEP PF00771.20 PSC70446.1 - 2.2 6.7 8.5 2.6 6.4 2.1 2.1 2 0 0 2 2 2 0 FHIPEP family CSRNP_N PF16019.5 PSC70446.1 - 3.2 7.6 10.2 4.7 7.1 2.2 2.2 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus Tim54 PF11711.8 PSC70446.1 - 3.8 6.2 9.1 6.8 5.4 0.3 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 DUF4834 PF16118.5 PSC70446.1 - 4 8.5 18.2 7.7 7.5 6.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TERB2 PF15101.6 PSC70446.1 - 6.5 6.8 20.2 5.6 7.0 6.4 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DnaJ_C PF01556.18 PSC70447.1 - 1e-40 139.2 0.0 1.4e-40 138.8 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PSC70447.1 - 7.7e-28 96.4 1.1 1.4e-27 95.6 1.1 1.5 1 0 0 1 1 1 1 DnaJ domain RPT PF13446.6 PSC70447.1 - 0.14 12.1 0.0 0.36 10.8 0.0 1.7 1 1 0 1 1 1 0 A repeated domain in UCH-protein HSP20 PF00011.21 PSC70448.1 - 1.9e-07 31.2 0.0 2.6e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family TFIID-18kDa PF02269.16 PSC70449.1 - 1.4e-22 79.5 0.2 5.3e-22 77.6 0.2 1.8 1 1 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit THOC2_N PF16134.5 PSC70449.1 - 1.8 7.1 4.4 2.4 6.7 4.4 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus TT_ORF1 PF02956.14 PSC70450.1 - 3.6 6.2 3.8 4.3 5.9 3.8 1.0 1 0 0 1 1 1 0 TT viral orf 1 TauE PF01925.19 PSC70451.1 - 2.7e-20 73.0 35.5 1.5e-12 47.7 4.6 4.7 5 1 0 5 5 5 3 Sulfite exporter TauE/SafE Bestrophin PF01062.21 PSC70451.1 - 2.8e-15 56.5 0.2 7.6e-15 55.1 0.2 1.7 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Ribonucleas_3_3 PF14622.6 PSC70451.1 - 7.4e-13 48.8 0.0 1.8e-12 47.5 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease-III-like CPBP PF02517.16 PSC70451.1 - 4.2e-10 39.9 3.4 7.2e-10 39.1 0.3 3.2 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease GYF PF02213.16 PSC70451.1 - 1.5e-07 31.0 0.1 0.00091 18.9 0.0 2.4 2 0 0 2 2 2 2 GYF domain Ribonuclease_3 PF00636.26 PSC70451.1 - 2e-06 28.4 0.0 7.2e-06 26.6 0.0 2.0 1 0 0 1 1 1 1 Ribonuclease III domain GYF_2 PF14237.6 PSC70451.1 - 2.6e-06 27.1 0.3 0.027 14.3 0.0 3.4 3 0 0 3 3 3 2 GYF domain 2 Tetraspanin PF00335.20 PSC70451.1 - 7.5e-05 22.6 0.0 7.5e-05 22.6 0.0 2.1 2 0 0 2 2 2 1 Tetraspanin family MIF4G PF02854.19 PSC70451.1 - 0.016 14.8 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 MIF4G domain PI3_PI4_kinase PF00454.27 PSC70453.1 - 1.9e-39 136.0 0.0 2.9e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3_PI4_kinase PF00454.27 PSC70454.1 - 1.9e-39 136.0 0.0 2.9e-39 135.4 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Phos_pyr_kin PF08543.12 PSC70455.1 - 6e-18 65.1 0.0 9.2e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 PSC70455.1 - 3e-10 39.9 0.0 8.6e-09 35.1 0.0 2.3 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Carb_kinase PF01256.17 PSC70455.1 - 0.018 14.6 0.5 0.099 12.1 0.0 2.2 2 0 0 2 2 2 0 Carbohydrate kinase HAD PF12710.7 PSC70455.1 - 0.11 12.9 0.2 0.59 10.5 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase AvrB_AvrC PF05394.11 PSC70456.1 - 0.069 12.3 0.1 0.074 12.2 0.1 1.0 1 0 0 1 1 1 0 Avirulence protein DASH_Duo1 PF08651.10 PSC70456.1 - 0.096 12.5 0.0 0.76 9.6 0.0 2.1 1 1 1 2 2 2 0 DASH complex subunit Duo1 LPP PF04728.13 PSC70456.1 - 0.099 13.1 1.9 0.81 10.1 0.5 2.3 2 0 0 2 2 2 0 Lipoprotein leucine-zipper Ribosomal_L23 PF00276.20 PSC70457.1 - 8.6e-17 61.3 0.1 1.9e-16 60.2 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L23 DUF4399 PF14347.6 PSC70457.1 - 0.076 13.4 0.1 0.19 12.1 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4399) Ydc2-catalyt PF09159.10 PSC70457.1 - 0.14 11.9 0.3 0.3 10.8 0.3 1.5 1 0 0 1 1 1 0 Mitochondrial resolvase Ydc2 / RNA splicing MRS1 zf-C3HC4_3 PF13920.6 PSC70458.1 - 6.6e-11 41.9 5.4 1.3e-10 41.0 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PSC70458.1 - 7.4e-05 22.5 8.2 0.00015 21.5 8.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PSC70458.1 - 0.00019 21.7 5.0 0.00044 20.5 5.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PSC70458.1 - 0.1 12.6 4.8 0.2 11.7 4.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PSC70458.1 - 0.12 12.3 6.5 0.28 11.0 6.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Gly-rich_Ago1 PF12764.7 PSC70458.1 - 0.16 12.8 3.9 0.41 11.5 3.9 1.6 1 0 0 1 1 1 0 Glycine-rich region of argonaut zf-RING_11 PF17123.5 PSC70458.1 - 0.61 9.9 2.6 1.7 8.4 2.6 1.8 1 0 0 1 1 1 0 RING-like zinc finger Peptidase_M48 PF01435.18 PSC70459.1 - 2.6e-44 151.3 0.0 4e-44 150.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M48_N PF16491.5 PSC70459.1 - 9.4e-44 149.5 0.0 1.4e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 CAAX prenyl protease N-terminal, five membrane helices Pkinase PF00069.25 PSC70459.1 - 3.7e-35 121.6 0.0 1.2e-34 119.9 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC70459.1 - 1e-29 103.7 0.0 3.3e-29 102.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PSC70459.1 - 3.7e-08 33.0 0.7 0.0058 16.4 0.4 3.4 2 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 PSC70459.1 - 6.2e-05 23.3 3.1 0.23 11.9 0.0 3.2 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) SprT-like PF10263.9 PSC70459.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 SprT-like family LRR_1 PF00560.33 PSC70459.1 - 0.19 12.4 1.9 34 5.5 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat Pkinase_fungal PF17667.1 PSC70459.1 - 0.2 10.4 0.0 0.29 9.9 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase DUF2268 PF10026.9 PSC70459.1 - 0.23 11.0 0.0 0.38 10.3 0.0 1.2 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) PAP2 PF01569.21 PSC70460.1 - 1.1e-09 38.1 5.3 1.1e-09 38.1 5.3 2.6 1 1 1 2 2 2 1 PAP2 superfamily DUF4064 PF13273.6 PSC70460.1 - 0.13 12.6 0.3 22 5.4 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Tom22 PF04281.13 PSC70460.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 HTH_1 PF00126.27 PSC70461.1 - 0.037 14.0 0.1 0.077 13.0 0.1 1.5 1 1 0 1 1 1 0 Bacterial regulatory helix-turn-helix protein, lysR family tRNA-synt_2d PF01409.20 PSC70462.1 - 1.8e-91 306.0 0.0 2.6e-91 305.4 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 PSC70462.1 - 5.6e-19 68.2 0.8 5.6e-19 68.2 0.8 2.4 3 0 0 3 3 3 1 PheRS DNA binding domain 3 PheRS_DBD1 PF18552.1 PSC70462.1 - 3.2e-11 42.8 0.2 6.7e-11 41.8 0.2 1.6 1 0 0 1 1 1 1 PheRS DNA binding domain 1 tRNA_synthFbeta PF17759.1 PSC70462.1 - 2.2e-08 33.8 0.0 4.7e-05 22.9 0.0 3.1 3 0 0 3 3 3 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 PSC70462.1 - 1.8e-05 24.0 1.3 0.0016 17.6 0.0 2.9 4 0 0 4 4 4 2 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 PSC70462.1 - 0.00026 21.0 0.0 0.00053 20.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD2 PF18554.1 PSC70462.1 - 0.00038 20.4 0.0 0.00098 19.1 0.0 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 2 OmpW PF03922.14 PSC70462.1 - 0.073 12.9 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 OmpW family ArfGap PF01412.18 PSC70463.1 - 6.4e-36 123.0 0.0 1.1e-35 122.2 0.0 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf ENTH PF01417.20 PSC70463.1 - 2.1e-27 95.7 0.0 3.2e-27 95.0 0.0 1.3 1 0 0 1 1 1 1 ENTH domain Cys_Met_Meta_PP PF01053.20 PSC70464.1 - 1e-85 287.6 0.0 1.8e-85 286.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme VPS13_C PF16909.5 PSC70464.1 - 1.3e-32 113.1 0.0 1e-31 110.1 0.0 2.2 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 PSC70464.1 - 4.7e-32 111.7 0.0 7.2e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 PSC70464.1 - 7.4e-26 91.1 0.0 4.4e-25 88.6 0.0 2.2 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 PSC70464.1 - 7.7e-23 80.8 0.0 1.4e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 Aminotran_1_2 PF00155.21 PSC70464.1 - 2.5e-06 26.9 0.0 6.3e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 PSC70464.1 - 0.00056 19.0 0.0 0.00098 18.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 PSC70464.1 - 0.011 15.0 0.0 0.027 13.7 0.0 1.6 1 0 0 1 1 1 0 Beta-eliminating lyase Cys_Met_Meta_PP PF01053.20 PSC70465.1 - 1e-85 287.6 0.0 1.8e-85 286.8 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme VPS13_C PF16909.5 PSC70465.1 - 1.3e-32 113.1 0.0 1e-31 110.1 0.0 2.2 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal VPS13 PF16908.5 PSC70465.1 - 4.7e-32 111.7 0.0 7.2e-32 111.1 0.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 PSC70465.1 - 7.4e-26 91.1 0.0 4.4e-25 88.6 0.0 2.2 3 0 0 3 3 3 1 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 PSC70465.1 - 7.7e-23 80.8 0.0 1.4e-22 79.9 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 Aminotran_1_2 PF00155.21 PSC70465.1 - 2.5e-06 26.9 0.0 6.3e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 PSC70465.1 - 0.00056 19.0 0.0 0.00098 18.2 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 PSC70465.1 - 0.011 15.0 0.0 0.027 13.7 0.0 1.6 1 0 0 1 1 1 0 Beta-eliminating lyase PFL-like PF02901.15 PSC70466.1 - 3.9e-187 623.8 0.0 4.9e-187 623.5 0.0 1.1 1 0 0 1 1 1 1 Pyruvate formate lyase-like Gly_radical PF01228.21 PSC70466.1 - 5.3e-41 139.4 0.0 1.2e-40 138.3 0.0 1.6 1 0 0 1 1 1 1 Glycine radical DUF3029 PF11230.8 PSC70466.1 - 0.00018 20.0 0.0 0.00062 18.3 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3029) PSI_PsaH PF03244.14 PSC70466.1 - 0.065 12.7 0.0 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 Photosystem I reaction centre subunit VI GTA_holin_3TM PF11351.8 PSC70467.1 - 0.05 14.2 0.1 0.076 13.6 0.1 1.2 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release PI3_PI4_kinase PF00454.27 PSC70468.1 - 1.5e-42 146.2 0.0 2.6e-42 145.4 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 PSC70468.1 - 1.9e-35 122.7 0.7 1.9e-35 122.7 0.7 1.6 2 0 0 2 2 2 1 FAT domain FATC PF02260.20 PSC70468.1 - 1.2e-12 47.3 0.7 3.6e-12 45.9 0.1 2.2 2 0 0 2 2 2 1 FATC domain TPR_2 PF07719.17 PSC70468.1 - 0.00026 20.8 0.3 0.18 12.0 0.1 3.7 2 0 0 2 2 2 1 Tetratricopeptide repeat UME PF08064.13 PSC70468.1 - 0.004 17.1 0.0 0.03 14.3 0.0 2.7 1 0 0 1 1 1 1 UME (NUC010) domain TPR_7 PF13176.6 PSC70468.1 - 0.0043 17.0 3.9 0.59 10.3 0.1 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat HEAT PF02985.22 PSC70468.1 - 0.021 15.0 8.3 5.6 7.5 0.0 5.6 5 0 0 5 5 5 0 HEAT repeat DUF3385 PF11865.8 PSC70468.1 - 0.054 13.4 0.0 0.23 11.3 0.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) MIT PF04212.18 PSC70468.1 - 0.11 12.6 0.1 0.49 10.5 0.1 2.2 1 0 0 1 1 1 0 MIT (microtubule interacting and transport) domain RINGv PF12906.7 PSC70469.1 - 3.8e-10 39.7 8.4 6.9e-10 38.9 8.4 1.5 1 0 0 1 1 1 1 RING-variant domain DUF2830 PF11125.8 PSC70469.1 - 0.17 11.9 0.0 0.35 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2830) zf-RING_2 PF13639.6 PSC70469.1 - 6.9 7.1 10.2 20 5.6 10.3 1.8 1 1 0 1 1 1 0 Ring finger domain OTU PF02338.19 PSC70470.1 - 2.1e-16 60.6 0.0 3.6e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease SEC-C PF02810.15 PSC70470.1 - 1.3e-05 24.9 9.5 1.3e-05 24.9 9.5 1.9 2 0 0 2 2 2 1 SEC-C motif DMA PF03474.14 PSC70470.1 - 0.00036 20.1 0.2 0.0006 19.4 0.2 1.3 1 0 0 1 1 1 1 DMRTA motif Peptidase_C65 PF10275.9 PSC70470.1 - 0.00042 19.8 0.3 0.41 10.0 0.2 2.3 2 0 0 2 2 2 2 Peptidase C65 Otubain UBA_4 PF14555.6 PSC70470.1 - 0.029 14.2 0.0 0.057 13.3 0.0 1.4 1 0 0 1 1 1 0 UBA-like domain CUE PF02845.16 PSC70470.1 - 0.042 13.6 0.0 0.074 12.8 0.0 1.4 1 0 0 1 1 1 0 CUE domain UBA PF00627.31 PSC70470.1 - 0.12 12.4 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 UBA/TS-N domain TFIIA PF03153.13 PSC70470.1 - 1.3 8.9 18.7 2 8.3 18.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRR_8 PF13855.6 PSC70472.1 - 1.2e-28 98.6 19.3 1.3e-07 31.2 1.1 6.3 4 2 2 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 PSC70472.1 - 6e-25 86.9 14.0 4.5e-05 23.7 0.0 8.4 3 1 5 9 9 9 9 Leucine Rich repeats (2 copies) UCH PF00443.29 PSC70472.1 - 6.7e-15 55.3 0.0 1.4e-14 54.2 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase LRR_1 PF00560.33 PSC70472.1 - 6.9 7.6 14.1 70 4.6 0.1 7.4 7 2 0 7 7 7 0 Leucine Rich Repeat PH PF00169.29 PSC70475.1 - 5e-11 43.1 0.1 7.9e-11 42.4 0.1 1.3 1 0 0 1 1 1 1 PH domain GED PF02212.18 PSC70475.1 - 6e-10 39.1 0.1 1.4e-09 37.9 0.1 1.6 1 0 0 1 1 1 1 Dynamin GTPase effector domain Dynamin_M PF01031.20 PSC70475.1 - 5.2e-08 32.4 0.0 1.2e-07 31.3 0.0 1.5 1 0 0 1 1 1 1 Dynamin central region PH_11 PF15413.6 PSC70475.1 - 0.00072 20.0 0.2 0.0015 19.0 0.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 PSC70475.1 - 0.033 14.5 0.0 0.12 12.6 0.0 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain TPR_1 PF00515.28 PSC70476.1 - 9.7e-09 34.7 0.1 0.0018 18.0 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PSC70476.1 - 9.8e-09 34.7 3.2 0.0023 17.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 PSC70476.1 - 4.1e-06 26.8 3.2 4.1e-06 26.8 3.2 2.8 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PSC70476.1 - 6.5e-05 23.4 12.8 0.0039 17.9 0.1 3.7 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PSC70476.1 - 0.00048 19.8 0.0 8.7 6.1 0.0 3.3 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 PSC70476.1 - 0.0068 16.5 0.0 1.1 9.7 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat ChAPs PF09295.10 PSC70476.1 - 0.016 14.2 0.1 0.019 14.0 0.1 1.1 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) TPR_16 PF13432.6 PSC70476.1 - 0.042 14.5 19.5 0.46 11.2 0.1 3.7 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 PSC70476.1 - 0.064 13.9 0.7 3.3 8.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 PSC70476.1 - 0.22 11.8 8.4 2.5 8.5 4.5 2.8 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 PSC70476.1 - 4.1 8.3 0.0 4.1 8.3 0.0 4.3 3 1 1 4 4 4 0 Tetratricopeptide repeat Toxin_18 PF08087.11 PSC70477.1 - 0.013 15.5 4.3 0.013 15.5 4.3 4.1 2 1 2 4 4 4 0 Conotoxin O-superfamily UPF0506 PF11703.8 PSC70477.1 - 0.31 11.4 39.5 0.66 10.4 12.0 3.1 1 1 2 3 3 3 0 UPF0506 Conotoxin_I2 PF17557.2 PSC70477.1 - 5.4 7.2 35.3 0.089 12.9 4.9 4.3 2 2 2 4 4 4 0 I2-superfamily conotoxins RRM_1 PF00076.22 PSC70478.1 - 4.5e-17 61.6 0.0 6.2e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PSC70478.1 - 0.0087 16.2 0.0 0.016 15.3 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif RRM_1 PF00076.22 PSC70479.1 - 5e-17 61.5 0.0 7e-17 61.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PSC70479.1 - 0.0095 16.0 0.0 0.017 15.2 0.0 1.4 1 1 0 1 1 1 1 RNA recognition motif Na_Ca_ex PF01699.24 PSC70482.1 - 2.9e-31 108.5 28.8 2e-17 63.6 7.5 2.4 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Ribosomal_S6e PF01092.19 PSC70483.1 - 4e-54 181.9 0.1 9.8e-54 180.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S6e rve PF00665.26 PSC70483.1 - 9.7e-32 109.7 0.0 3.5e-18 65.9 0.0 3.5 3 0 0 3 3 3 3 Integrase core domain Whib PF02467.16 PSC70483.1 - 0.0011 19.6 0.8 3.5 8.3 0.1 3.0 2 0 0 2 2 2 2 Transcription factor WhiB rve_3 PF13683.6 PSC70483.1 - 0.013 15.3 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain RTTN_N PF14726.6 PSC70483.1 - 0.015 16.1 0.2 15 6.4 0.0 2.8 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning Skp1 PF01466.19 PSC70483.1 - 0.026 14.6 0.2 17 5.6 0.0 4.1 4 0 0 4 4 4 0 Skp1 family, dimerisation domain CbtB PF09489.10 PSC70484.1 - 4.5 7.4 5.0 8 6.7 0.2 2.2 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtB) tRNA-synt_1b PF00579.25 PSC70485.1 - 1.7e-63 214.7 0.0 1.2e-62 211.9 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) S4 PF01479.25 PSC70485.1 - 1e-07 31.6 0.1 2.2e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 S4 domain TyrRSs_C PF16714.5 PSC70485.1 - 0.028 14.2 0.5 0.46 10.3 0.5 2.3 1 1 0 1 1 1 0 Tyrosyl-tRNA synthetase C-terminal domain Topo-VIb_trans PF09239.11 PSC70486.1 - 3.1e-54 183.1 0.0 8.6e-54 181.7 0.0 1.8 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer Ribosomal_S8e PF01201.22 PSC70486.1 - 1.5e-51 174.1 0.8 1.5e-51 174.1 0.8 2.8 3 0 0 3 3 3 1 Ribosomal protein S8e HATPase_c_3 PF13589.6 PSC70486.1 - 5.7e-09 35.9 0.7 1.9e-07 31.0 0.1 2.6 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PSC70486.1 - 5.2e-07 30.2 0.3 1.6e-05 25.4 0.3 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FbpA PF05833.11 PSC70486.1 - 0.002 16.9 1.2 0.0077 15.0 0.0 2.1 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) Topo-VIb_trans PF09239.11 PSC70487.1 - 3.1e-54 183.1 0.0 8.7e-54 181.6 0.0 1.8 1 0 0 1 1 1 1 Topoisomerase VI B subunit, transducer Ribosomal_S8e PF01201.22 PSC70487.1 - 1.6e-51 174.1 0.8 1.6e-51 174.1 0.8 2.8 2 0 0 2 2 2 1 Ribosomal protein S8e HATPase_c_3 PF13589.6 PSC70487.1 - 5.8e-09 35.9 0.7 1.9e-07 31.0 0.1 2.6 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PSC70487.1 - 5.2e-07 30.2 0.3 1.6e-05 25.4 0.3 2.5 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FbpA PF05833.11 PSC70487.1 - 0.002 16.9 1.2 0.0078 15.0 0.0 2.1 2 0 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) ADH_zinc_N_2 PF13602.6 PSC70488.1 - 3.6e-21 76.6 0.8 1.3e-20 74.8 0.8 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RRM_1 PF00076.22 PSC70488.1 - 7.9e-15 54.4 0.0 0.00033 20.4 0.0 4.5 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADH_zinc_N PF00107.26 PSC70488.1 - 3.9e-12 46.3 0.6 8.2e-12 45.2 0.6 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PSC70488.1 - 6e-06 26.1 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain LRR_8 PF13855.6 PSC70488.1 - 4.1e-05 23.3 3.1 4.1e-05 23.3 3.1 4.6 4 1 1 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 PSC70488.1 - 0.0082 16.5 3.3 0.0082 16.5 3.3 4.2 3 2 2 5 5 5 2 Leucine Rich repeats (2 copies) DUF2855 PF11017.8 PSC70488.1 - 0.026 14.3 0.1 0.041 13.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) EMP24_GP25L PF01105.24 PSC70489.1 - 1.3e-14 54.6 0.0 2.3e-14 53.8 0.0 1.4 1 1 0 1 1 1 1 emp24/gp25L/p24 family/GOLD DUF3040 PF11239.8 PSC70489.1 - 0.14 12.4 4.8 2.2 8.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) RWP-RK PF02042.15 PSC70490.1 - 3e-17 62.3 0.0 9.5e-17 60.7 0.0 1.9 2 0 0 2 2 2 1 RWP-RK domain Dpy-30 PF05186.13 PSC70491.1 - 2.5e-16 59.1 0.1 5.1e-16 58.1 0.1 1.5 1 0 0 1 1 1 1 Dpy-30 motif Metallophos_2 PF12850.7 PSC70491.1 - 5.9e-14 52.6 0.0 9.3e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Lipase_GDSL_2 PF13472.6 PSC70491.1 - 1.9e-07 31.6 0.1 4e-07 30.6 0.1 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family RIIa PF02197.17 PSC70491.1 - 0.07 12.8 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit Metallophos PF00149.28 PSC70491.1 - 0.13 12.7 0.2 3.2 8.2 0.1 2.3 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase WD40 PF00400.32 PSC70492.1 - 2e-15 56.9 10.1 0.033 15.1 0.0 10.0 11 0 0 11 11 11 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC70492.1 - 5.4e-13 49.1 0.0 0.085 13.2 0.0 6.2 4 2 0 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PSC70492.1 - 0.00046 19.3 1.0 0.84 8.5 0.0 4.9 6 0 0 6 6 6 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Amino_oxidase PF01593.24 PSC70494.1 - 6.5e-57 193.8 5.9 1.8e-34 119.8 0.3 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PSC70494.1 - 7.5e-10 38.9 0.2 2.7e-09 37.1 0.2 2.0 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 PSC70494.1 - 2.4e-05 23.7 0.2 4.7e-05 22.8 0.2 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PSC70494.1 - 0.0012 19.4 0.1 0.0025 18.3 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PSC70494.1 - 0.0025 17.1 0.1 0.0065 15.7 0.1 1.6 1 0 0 1 1 1 1 Thi4 family GIDA PF01134.22 PSC70494.1 - 0.0053 15.9 1.0 0.0094 15.1 1.0 1.4 1 0 0 1 1 1 1 Glucose inhibited division protein A HI0933_like PF03486.14 PSC70494.1 - 0.0059 15.4 0.5 0.0094 14.7 0.5 1.2 1 0 0 1 1 1 1 HI0933-like protein Pyr_redox_3 PF13738.6 PSC70494.1 - 0.039 13.2 0.7 0.058 12.6 0.7 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 PSC70494.1 - 0.084 11.9 3.2 0.12 11.4 0.8 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 PSC70494.1 - 0.39 10.0 2.8 0.94 8.7 2.8 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain CAF1 PF04857.20 PSC70495.1 - 2.5e-19 69.6 1.0 1.9e-09 37.2 0.0 2.7 1 1 1 2 2 2 2 CAF1 family ribonuclease UPF0051 PF01458.17 PSC70496.1 - 6.6e-62 209.0 0.1 8.7e-62 208.6 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) DNA_photolyase PF00875.18 PSC70497.1 - 2.6e-32 112.1 0.0 4.9e-32 111.2 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase PCRF PF03462.18 PSC70498.1 - 6e-69 231.8 2.8 1.2e-68 230.8 2.8 1.5 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 PSC70498.1 - 4.4e-36 123.3 0.7 1.1e-35 122.0 0.7 1.7 1 0 0 1 1 1 1 RF-1 domain Cyclin_N PF00134.23 PSC70498.1 - 1.9e-30 105.2 0.3 1.8e-28 98.8 0.0 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 PSC70498.1 - 2.8e-18 66.1 3.8 7.1e-18 64.8 3.8 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain Ribosomal_L3 PF00297.22 PSC70498.1 - 1.7e-17 63.4 4.0 5e-16 58.6 1.8 2.9 2 1 1 3 3 3 1 Ribosomal protein L3 Med9 PF07544.13 PSC70498.1 - 0.04 14.0 0.6 0.13 12.4 0.6 1.9 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 ABC_tran_CTD PF16326.5 PSC70498.1 - 0.14 12.4 0.1 0.14 12.4 0.1 3.2 2 1 1 3 3 3 0 ABC transporter C-terminal domain HalX PF08663.10 PSC70498.1 - 1.3 9.4 11.7 13 6.2 2.1 3.8 1 1 2 3 3 3 0 HalX domain Chloroa_b-bind PF00504.21 PSC70499.1 - 8.8e-45 153.1 0.0 1.1e-44 152.8 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Haspin_kinase PF12330.8 PSC70500.1 - 5.1e-48 163.9 0.0 7.1e-48 163.4 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase PF00069.25 PSC70500.1 - 0.11 11.8 0.0 2.8 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein kinase domain PEN-2 PF10251.9 PSC70501.1 - 5.1e-15 55.7 0.8 6.5e-15 55.3 0.8 1.1 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase RPAP2_Rtr1 PF04181.13 PSC70502.1 - 5.2e-10 39.5 0.0 1.2e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Rtr1/RPAP2 family PPI_Ypi1 PF07491.11 PSC70502.1 - 0.18 11.6 0.3 0.44 10.4 0.3 1.6 1 0 0 1 1 1 0 Protein phosphatase inhibitor RPAP2_Rtr1 PF04181.13 PSC70503.1 - 5.2e-10 39.5 0.0 1.2e-09 38.4 0.0 1.7 1 0 0 1 1 1 1 Rtr1/RPAP2 family PPI_Ypi1 PF07491.11 PSC70503.1 - 0.19 11.6 0.3 0.44 10.4 0.3 1.6 1 0 0 1 1 1 0 Protein phosphatase inhibitor Sortilin-Vps10 PF15902.5 PSC70504.1 - 0.074 11.8 0.1 0.87 8.3 0.0 2.2 2 1 0 2 2 2 0 Sortilin, neurotensin receptor 3, BNR PF02012.20 PSC70504.1 - 0.14 12.2 9.1 0.55 10.4 0.5 3.7 3 0 0 3 3 3 0 BNR/Asp-box repeat Mon2_C PF16206.5 PSC70505.1 - 1.2e-36 126.3 0.8 1e-30 106.6 0.0 4.5 4 1 0 4 4 4 3 C-terminal region of Mon2 protein DCB PF16213.5 PSC70505.1 - 2.8e-24 85.7 0.5 7.1e-24 84.4 0.5 1.7 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 PSC70505.1 - 3.1e-18 66.2 0.0 9.3e-18 64.6 0.0 1.9 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 PSC70505.1 - 2.2e-07 30.6 0.0 3.2e-06 26.9 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) HEAT PF02985.22 PSC70505.1 - 0.0018 18.3 3.5 0.0065 16.6 0.0 4.0 4 0 0 4 4 4 1 HEAT repeat SIL1 PF16782.5 PSC70505.1 - 0.28 10.4 0.0 0.5 9.5 0.0 1.3 1 0 0 1 1 1 0 Nucleotide exchange factor SIL1 TrbC PF04956.13 PSC70505.1 - 0.38 11.0 2.8 8 6.8 0.9 3.3 2 0 0 2 2 2 0 TrbC/VIRB2 family Utp11 PF03998.13 PSC70506.1 - 4.8e-72 242.8 12.5 5.5e-72 242.6 12.5 1.0 1 0 0 1 1 1 1 Utp11 protein SLATT_5 PF18160.1 PSC70506.1 - 0.03 13.7 0.1 0.058 12.7 0.1 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Pkinase PF00069.25 PSC70507.1 - 3.2e-51 174.2 0.0 4.8e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC70507.1 - 1.1e-50 172.4 0.0 1.6e-50 171.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Sulfotransfer_2 PF03567.14 PSC70507.1 - 1.6e-15 57.7 1.4 1.9e-08 34.5 0.0 3.8 3 1 1 4 4 4 3 Sulfotransferase family Ank_2 PF12796.7 PSC70507.1 - 1.7e-07 31.7 0.0 3.8e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC70507.1 - 1.8e-07 31.5 0.0 0.00019 22.0 0.0 2.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC70507.1 - 8.5e-06 26.0 0.0 0.00067 19.9 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PSC70507.1 - 0.00011 22.5 0.0 0.00035 20.9 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeat Ank_3 PF13606.6 PSC70507.1 - 0.00094 19.5 0.0 0.0054 17.1 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat APH PF01636.23 PSC70507.1 - 0.011 15.7 0.0 0.011 15.7 0.0 3.9 4 0 0 4 4 4 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PSC70507.1 - 0.083 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Methyltransf_24 PF13578.6 PSC70508.1 - 0.051 14.6 0.0 0.1 13.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain SRP_TPR_like PF17004.5 PSC70509.1 - 9.3e-14 51.4 0.0 5.7e-13 48.9 0.0 2.2 2 0 0 2 2 2 1 Putative TPR-like repeat SRP72 PF08492.12 PSC70509.1 - 3.6e-11 43.3 11.7 3.6e-11 43.3 11.7 2.2 2 1 1 3 3 2 1 SRP72 RNA-binding domain ANAPC3 PF12895.7 PSC70509.1 - 2.6e-05 24.4 12.1 0.31 11.3 1.1 4.5 2 1 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 PSC70509.1 - 0.00025 20.9 46.0 0.81 9.9 0.2 9.5 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 PSC70509.1 - 0.00065 20.3 5.5 0.0044 17.6 0.6 9.4 7 2 2 9 9 8 4 Tetratricopeptide repeat TPR_19 PF14559.6 PSC70509.1 - 0.0024 18.3 0.8 0.0024 18.3 0.8 7.9 4 3 5 9 9 9 4 Tetratricopeptide repeat TPR_9 PF13371.6 PSC70509.1 - 0.0032 17.6 0.3 0.0032 17.6 0.3 6.6 5 2 2 7 7 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 PSC70509.1 - 0.025 14.9 0.9 0.025 14.9 0.9 7.6 5 3 4 9 9 9 0 Tetratricopeptide repeat TPR_14 PF13428.6 PSC70509.1 - 0.054 14.3 69.6 0.17 12.8 0.2 10.9 5 4 6 11 11 11 0 Tetratricopeptide repeat TPR_11 PF13414.6 PSC70509.1 - 0.13 12.0 15.7 2.7 7.7 0.1 5.8 6 0 0 6 6 6 0 TPR repeat DUF2225 PF09986.9 PSC70509.1 - 0.24 11.1 0.5 2.1 8.0 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_17 PF13431.6 PSC70509.1 - 0.31 11.5 0.0 0.31 11.5 0.0 6.3 8 0 0 8 8 7 0 Tetratricopeptide repeat PPR_1 PF12854.7 PSC70509.1 - 1.8 8.4 4.7 4.4 7.1 0.2 3.7 3 0 0 3 3 3 0 PPR repeat PPR PF01535.20 PSC70509.1 - 1.9 8.9 6.4 64 4.1 0.1 5.2 5 0 0 5 5 5 0 PPR repeat TPR_1 PF00515.28 PSC70509.1 - 2.4 8.1 24.0 9.4 6.2 0.3 7.1 7 0 0 7 7 7 0 Tetratricopeptide repeat Porphobil_deam PF01379.20 PSC70510.1 - 3e-77 258.7 0.0 4.3e-77 258.2 0.0 1.2 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 PSC70510.1 - 4.6e-14 52.6 0.0 8.7e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain LysR_substrate PF03466.20 PSC70510.1 - 0.0065 15.9 0.8 0.23 10.8 0.0 2.9 3 0 0 3 3 3 1 LysR substrate binding domain SBP_bac_3 PF00497.20 PSC70510.1 - 0.0073 15.8 0.1 0.05 13.0 0.1 2.1 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 B3 PF02362.21 PSC70511.1 - 2.2e-07 30.6 0.0 4.9e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 B3 DNA binding domain SelP_N PF04592.14 PSC70511.1 - 7.1 6.0 6.3 12 5.3 6.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region B3 PF02362.21 PSC70512.1 - 2.2e-07 30.6 0.0 4.9e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 B3 DNA binding domain SelP_N PF04592.14 PSC70512.1 - 7.1 6.0 6.3 12 5.3 6.3 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region VWA_2 PF13519.6 PSC70513.1 - 3.7e-24 85.4 0.3 1.1e-23 83.9 0.1 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.14 PSC70513.1 - 1e-07 31.9 0.0 1.9e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Ssl1-like UIM PF02809.20 PSC70513.1 - 1.2e-07 31.1 19.8 0.016 15.1 5.3 3.8 3 0 0 3 3 3 3 Ubiquitin interaction motif Glyco_transf_52 PF07922.11 PSC70513.1 - 0.031 13.6 0.1 0.044 13.1 0.1 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 52 RAP80_UIM PF18282.1 PSC70513.1 - 2.5 8.0 12.8 0.55 10.1 1.8 3.3 3 0 0 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif YadA_anchor PF03895.15 PSC70514.1 - 0.031 14.4 3.9 0.088 12.9 4.3 1.6 2 0 0 2 2 2 0 YadA-like membrane anchor domain DUF4743 PF15916.5 PSC70515.1 - 1.4e-31 109.0 0.0 2.4e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4743) NUDIX PF00293.28 PSC70515.1 - 3.5e-06 27.1 0.0 6.1e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain RNase_H2_suC PF08615.11 PSC70516.1 - 5.8e-16 58.9 0.0 9.1e-16 58.3 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) LRR_8 PF13855.6 PSC70516.1 - 0.00062 19.5 1.4 0.12 12.2 0.0 3.9 4 1 0 5 5 5 1 Leucine rich repeat LRR_4 PF12799.7 PSC70516.1 - 0.011 16.2 0.0 0.2 12.2 0.0 3.1 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PSC70516.1 - 0.25 11.5 1.1 3.3 8.0 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich repeat RNase_H2_suC PF08615.11 PSC70517.1 - 6.2e-16 58.9 0.0 9.7e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) LRR_8 PF13855.6 PSC70517.1 - 0.001 18.8 1.8 0.12 12.1 0.0 3.8 4 1 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.7 PSC70517.1 - 0.013 15.9 0.0 0.21 12.1 0.0 3.0 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PSC70517.1 - 0.27 11.4 1.1 3.5 7.9 0.0 3.4 4 0 0 4 4 4 0 Leucine Rich repeat Glyco_transf_92 PF01697.27 PSC70518.1 - 4.5e-21 75.7 0.0 5.9e-21 75.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PSC70518.1 - 2.9e-12 46.9 0.1 5.2e-12 46.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Annexin_like PF18411.1 PSC70518.1 - 0.14 12.4 0.0 0.37 11.1 0.0 1.7 2 0 0 2 2 2 0 Annexin-like domain Glyco_transf_92 PF01697.27 PSC70519.1 - 3e-21 76.2 0.0 3.9e-21 75.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PSC70519.1 - 6.7e-12 45.8 0.1 1.2e-11 45.0 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Annexin_like PF18411.1 PSC70519.1 - 0.14 12.4 0.0 0.39 11.0 0.0 1.7 2 0 0 2 2 2 0 Annexin-like domain O-FucT PF10250.9 PSC70520.1 - 1.1e-07 31.9 0.0 1.1e-05 25.4 0.0 2.4 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Ribosomal_L1 PF00687.21 PSC70521.1 - 1e-51 175.6 0.0 1.3e-51 175.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Exostosin PF03016.15 PSC70522.1 - 1.4e-18 67.1 0.1 1.1e-16 60.9 0.0 2.1 2 0 0 2 2 2 2 Exostosin family ThiF PF00899.21 PSC70523.1 - 2.3e-71 240.0 0.0 3.4e-71 239.4 0.0 1.2 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 PSC70523.1 - 3.2e-19 69.3 0.0 5.7e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 PSC70523.1 - 4.5e-09 36.6 0.0 2.5e-07 30.9 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site Nucleotid_trans PF03407.16 PSC70523.1 - 4e-05 23.7 0.0 7.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase NAD_binding_7 PF13241.6 PSC70523.1 - 0.0087 16.5 0.1 0.022 15.2 0.1 1.7 1 0 0 1 1 1 1 Putative NAD(P)-binding UBA2_C PF16195.5 PSC70523.1 - 0.014 16.0 5.9 0.037 14.7 5.9 1.7 1 0 0 1 1 1 0 SUMO-activating enzyme subunit 2 C-terminus Mannosyl_trans3 PF11051.8 PSC70523.1 - 0.036 13.4 0.1 0.1 11.9 0.0 1.6 2 0 0 2 2 2 0 Mannosyltransferase putative Shikimate_DH PF01488.20 PSC70523.1 - 0.047 13.8 0.2 0.33 11.0 0.1 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF3597 PF12200.8 PSC70523.1 - 3.1 8.3 4.6 7.2 7.2 4.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3597) RNA_pol_Rpb2_6 PF00562.28 PSC70524.1 - 2e-126 422.2 1.7 4.8e-125 417.7 0.7 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 PSC70524.1 - 4.5e-65 219.0 0.0 6.9e-65 218.4 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 PSC70524.1 - 2.2e-52 177.4 0.0 5.3e-52 176.2 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 PSC70524.1 - 1.4e-33 115.2 0.5 6.8e-33 112.9 0.1 2.5 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 7 Maf PF02545.14 PSC70524.1 - 4.6e-30 104.7 0.0 8.3e-30 103.8 0.0 1.4 1 0 0 1 1 1 1 Maf-like protein RNA_pol_Rpb2_3 PF04565.16 PSC70524.1 - 1.4e-26 92.4 0.0 3.8e-26 91.0 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 PSC70524.1 - 1.9e-23 82.5 0.6 5.7e-23 81.0 0.6 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 PSC70524.1 - 6.3e-18 65.1 0.1 1.6e-17 63.8 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 OrfB_Zn_ribbon PF07282.11 PSC70524.1 - 0.21 11.5 1.2 0.54 10.2 1.2 1.6 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Glycolytic PF00274.19 PSC70525.1 - 9.8e-159 527.7 0.0 1.3e-158 527.3 0.0 1.1 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I RCC1 PF00415.18 PSC70525.1 - 3.6e-57 190.8 12.7 8.1e-10 39.2 0.1 7.4 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PSC70525.1 - 1.5e-30 104.3 22.8 1.3e-07 31.3 0.4 7.0 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Peptidase_C25_C PF03785.14 PSC70525.1 - 0.17 11.7 0.0 17 5.3 0.0 2.6 2 0 0 2 2 2 0 Peptidase family C25, C terminal ig-like domain ABC2_membrane PF01061.24 PSC70526.1 - 7.4e-12 45.1 22.3 2.3e-07 30.5 15.2 3.2 2 1 1 3 3 3 3 ABC-2 type transporter ABC_tran PF00005.27 PSC70526.1 - 1.5e-09 38.5 0.0 3e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 ABC transporter WD40 PF00400.32 PSC70526.1 - 0.4 11.6 1.9 5.3 8.1 0.0 3.4 4 0 0 4 4 4 0 WD domain, G-beta repeat Spt20 PF12090.8 PSC70526.1 - 3 7.4 7.2 4.6 6.8 7.2 1.1 1 0 0 1 1 1 0 Spt20 family O-FucT PF10250.9 PSC70527.1 - 2.8e-09 37.2 0.0 1.7e-08 34.5 0.0 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase GDP_Man_Dehyd PF16363.5 PSC70528.1 - 2.3e-153 510.5 0.0 2.6e-153 510.3 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PSC70528.1 - 1.1e-71 241.2 0.1 1.3e-71 240.9 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 PSC70528.1 - 0.00026 20.2 0.0 0.00041 19.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 PSC70528.1 - 0.028 13.6 0.0 0.04 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SAC3_GANP PF03399.16 PSC70529.1 - 3.7e-18 65.9 0.0 3.7e-18 65.9 0.0 2.6 2 1 0 2 2 2 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 PSC70529.1 - 0.0066 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family DUF4569 PF15133.6 PSC70529.1 - 1.7 8.3 10.3 49 3.5 9.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4569) eIF-3_zeta PF05091.12 PSC70529.1 - 6 5.7 17.2 9.9 5.0 17.2 1.4 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Hamartin PF04388.12 PSC70529.1 - 7.8 5.0 12.4 11 4.6 12.4 1.1 1 0 0 1 1 1 0 Hamartin protein Vac7 PF12751.7 PSC70529.1 - 7.9 5.8 12.7 12 5.2 12.7 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 CPP1-like PF11833.8 PSC70530.1 - 2.6e-09 37.0 4.4 8e-09 35.4 4.4 2.0 1 1 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DnaJ PF00226.31 PSC70530.1 - 0.00058 19.9 0.0 0.0012 19.0 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain CS PF04969.16 PSC70531.1 - 5.4e-14 53.0 0.0 9.2e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 CS domain PikAIV_N PF18605.1 PSC70531.1 - 2.3 7.9 4.8 23 4.7 0.6 2.5 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain Ldh_1_C PF02866.18 PSC70532.1 - 5.1e-47 159.9 0.0 8.3e-47 159.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 PSC70532.1 - 3.6e-46 156.7 0.1 5.9e-46 156.1 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 PSC70532.1 - 1.3e-05 24.4 0.0 2.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 PSC70532.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase Ldh_1_C PF02866.18 PSC70533.1 - 5.1e-47 159.9 0.0 8.3e-47 159.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 PSC70533.1 - 3.6e-46 156.7 0.1 5.9e-46 156.1 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 PSC70533.1 - 1.3e-05 24.4 0.0 2.2e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Glyco_hydro_4 PF02056.16 PSC70533.1 - 0.074 12.6 0.0 0.15 11.6 0.0 1.5 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase CPL PF08144.11 PSC70534.1 - 5.7e-09 36.5 0.0 1.1e-06 29.1 0.0 3.2 3 0 0 3 3 3 1 CPL (NUC119) domain Cytochrom_B_C PF00032.17 PSC70535.1 - 2.6e-18 66.2 0.0 1.3e+02 2.9 0.0 16.7 17 0 0 17 17 17 0 Cytochrome b(C-terminal)/b6/petD O-FucT PF10250.9 PSC70535.1 - 2.9e-10 40.4 0.0 1.9e-09 37.7 0.0 2.2 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase HA2 PF04408.23 PSC70535.1 - 1.9e-07 31.3 151.5 0.41 10.9 2.4 18.0 6 2 4 10 10 10 5 Helicase associated domain (HA2) DUF3040 PF11239.8 PSC70536.1 - 0.043 14.1 0.8 0.84 9.9 1.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3040) RskA PF10099.9 PSC70536.1 - 0.1 12.9 8.4 0.12 12.7 8.4 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DnaJ_CXXCXGXG PF00684.19 PSC70536.1 - 0.43 11.0 19.8 1.6 9.1 19.8 2.2 1 1 0 1 1 1 0 DnaJ central domain Anti-TRAP PF15777.5 PSC70536.1 - 4.3 7.4 15.6 6.9e+02 0.3 15.6 3.2 1 1 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein RRM_1 PF00076.22 PSC70537.1 - 5.1e-18 64.7 0.2 1.8e-17 62.9 0.2 1.9 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PSC70537.1 - 0.0013 18.8 0.0 0.0024 17.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif RRM_8 PF11835.8 PSC70537.1 - 0.2 11.9 0.0 2.5 8.4 0.0 2.2 1 1 0 1 1 1 0 RRM-like domain EIF4E-T PF10477.9 PSC70537.1 - 2.3 6.9 30.3 2.5 6.8 30.3 1.0 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E RR_TM4-6 PF06459.12 PSC70537.1 - 3 7.6 7.1 3.5 7.4 7.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Epimerase PF01370.21 PSC70538.1 - 4.7e-48 163.8 0.0 6e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PSC70538.1 - 1.9e-07 30.8 0.0 2.5e-06 27.1 0.0 2.2 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 PSC70538.1 - 0.012 14.8 0.0 0.016 14.3 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain O-FucT PF10250.9 PSC70539.1 - 4.6e-20 72.6 0.1 1.9e-15 57.4 0.1 2.7 2 1 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase DUF2169 PF09937.9 PSC70539.1 - 0.096 12.1 0.2 0.15 11.5 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2169) Acetyltransf_16 PF05301.11 PSC70539.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase, Mec-17 Epimerase PF01370.21 PSC70540.1 - 1.1e-68 231.4 0.0 1.4e-68 231.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PSC70540.1 - 1.2e-15 57.7 0.0 4e-15 56.0 0.0 1.8 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 PSC70540.1 - 5.9e-08 32.2 0.0 7.6e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Fer4_14 PF13394.6 PSC70540.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain Proteasome PF00227.26 PSC70541.1 - 5.6e-54 182.5 0.0 6.5e-54 182.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit ABC_membrane_2 PF06472.15 PSC70542.1 - 2.2e-48 165.0 4.8 4.1e-48 164.1 4.8 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 PSC70542.1 - 8.7e-17 61.9 0.0 1.9e-15 57.6 0.0 2.6 1 1 0 1 1 1 1 ABC transporter SbmA_BacA PF05992.12 PSC70542.1 - 1.8e-13 50.7 3.3 4.5e-13 49.3 3.3 1.6 1 1 0 1 1 1 1 SbmA/BacA-like family NACHT PF05729.12 PSC70542.1 - 0.0015 18.5 0.0 0.0035 17.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain AAA_30 PF13604.6 PSC70542.1 - 0.0035 17.1 1.5 0.026 14.2 0.3 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PSC70542.1 - 0.0036 17.7 0.1 0.0036 17.7 0.1 2.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 PSC70542.1 - 0.016 15.1 0.1 0.051 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PSC70542.1 - 0.016 14.7 0.1 3.1 7.2 0.0 2.6 3 0 0 3 3 3 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 PSC70542.1 - 0.022 14.7 0.1 0.042 13.8 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 PSC70542.1 - 0.025 14.9 0.6 0.15 12.4 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 PSC70542.1 - 0.03 14.8 0.1 0.18 12.2 0.2 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 PSC70542.1 - 0.076 12.8 2.7 0.084 12.6 0.5 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_membrane PF00664.23 PSC70542.1 - 0.24 11.0 4.8 0.58 9.7 4.8 1.6 1 1 0 1 1 1 0 ABC transporter transmembrane region Methyltransf_33 PF10017.9 PSC70543.1 - 3.2e-76 256.4 0.0 5.4e-76 255.7 0.0 1.3 1 0 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent CG-1 PF03859.16 PSC70543.1 - 5.1e-45 152.0 0.0 8.4e-45 151.3 0.0 1.3 1 0 0 1 1 1 1 CG-1 domain FGE-sulfatase PF03781.16 PSC70543.1 - 7.3e-18 65.1 0.0 5.2e-11 42.6 0.0 2.8 2 1 1 3 3 3 2 Sulfatase-modifying factor enzyme 1 DinB_2 PF12867.7 PSC70543.1 - 2.6e-06 28.0 1.5 1.5e-05 25.5 0.1 3.1 2 0 0 2 2 2 1 DinB superfamily Methyltransf_12 PF08242.12 PSC70543.1 - 0.017 15.8 0.0 0.051 14.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 PSC70543.1 - 0.032 14.9 0.0 0.12 13.0 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Med26 PF08711.11 PSC70544.1 - 8.6e-08 32.1 0.0 1.5e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-CCCH PF00642.24 PSC70544.1 - 0.002 18.0 2.8 0.0033 17.3 2.8 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PSC70544.1 - 0.014 15.1 5.6 0.026 14.3 5.6 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 PSC70544.1 - 0.034 14.6 5.6 0.069 13.6 5.6 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger EPL1 PF10513.9 PSC70544.1 - 0.8 10.1 7.3 0.15 12.5 1.9 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like Spt20 PF12090.8 PSC70544.1 - 0.96 9.0 31.6 0.061 12.9 24.4 2.2 2 0 0 2 2 2 0 Spt20 family eIF-3_zeta PF05091.12 PSC70544.1 - 1.4 7.9 9.0 2.3 7.1 9.0 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) zf_CCCH_4 PF18345.1 PSC70544.1 - 1.6 8.9 5.7 2.9 8.1 5.7 1.4 1 0 0 1 1 1 0 Zinc finger domain Orf78 PF06024.12 PSC70544.1 - 1.8 8.9 2.8 4 7.8 2.8 1.5 1 0 0 1 1 1 0 Orf78 (ac78) DUF4770 PF15994.5 PSC70544.1 - 3.4 7.9 9.7 9.3 6.5 9.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DUF775 PF05603.12 PSC70544.1 - 5.2 6.6 10.5 12 5.4 10.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF775) E1-E2_ATPase PF00122.20 PSC70545.1 - 9.7e-51 171.9 0.1 2.1e-50 170.8 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HMA PF00403.26 PSC70545.1 - 1.2e-41 140.9 0.2 1.9e-12 47.4 0.1 3.6 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase PF00702.26 PSC70545.1 - 3.3e-40 138.6 17.9 4.8e-31 108.7 10.1 2.9 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 PSC70545.1 - 1.2e-05 25.2 0.1 8.9e-05 22.3 0.1 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase zf-CCCH_3 PF15663.5 PSC70545.1 - 0.00048 20.3 3.2 0.00048 20.3 3.2 2.0 1 1 0 1 1 1 1 Zinc-finger containing family HAD PF12710.7 PSC70545.1 - 0.00056 20.4 0.1 0.0041 17.6 0.1 2.5 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase FeS_assembly_P PF01883.19 PSC70545.1 - 0.067 13.4 12.9 8.4 6.7 0.0 5.1 4 0 0 4 4 4 0 Iron-sulfur cluster assembly protein zf_CCCH_4 PF18345.1 PSC70545.1 - 1.1 9.4 20.9 0.18 11.9 3.5 4.2 4 0 0 4 4 4 0 Zinc finger domain Nab2p_Zf1 PF18260.1 PSC70545.1 - 6 6.9 15.2 20 5.2 0.6 2.8 2 0 0 2 2 2 0 Nuclear polyadenylated RNA-binding 2 protein CCCH zinc finger 1 Filamin PF00630.19 PSC70546.1 - 0.0067 17.2 0.0 0.012 16.4 0.0 1.3 1 0 0 1 1 1 1 Filamin/ABP280 repeat RAG1 PF12940.7 PSC70546.1 - 0.22 9.6 0.0 0.31 9.1 0.0 1.1 1 0 0 1 1 1 0 Recombination-activation protein 1 (RAG1), recombinase DUF1598 PF07643.11 PSC70547.1 - 3.2 8.0 5.8 4.7 7.5 1.3 3.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1598) DUF563 PF04577.14 PSC70548.1 - 5.1e-13 49.6 0.0 8.1e-13 49.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) DUF3323 PF11796.8 PSC70548.1 - 0.73 9.7 6.4 5 7.0 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function N-terminus (DUF3323) RRM_1 PF00076.22 PSC70549.1 - 5.2e-25 87.1 0.0 3.5e-08 33.2 0.0 5.5 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADH_zinc_N_2 PF13602.6 PSC70549.1 - 9.7e-25 88.2 1.3 8.3e-15 56.0 0.2 3.0 2 0 0 2 2 2 2 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 PSC70549.1 - 2.8e-14 53.2 7.4 1.5e-11 44.4 0.8 2.9 3 0 0 3 3 3 2 Zinc-binding dehydrogenase ADH_N PF08240.12 PSC70549.1 - 5.9e-08 32.6 3.3 0.006 16.5 0.2 2.8 2 1 0 2 2 2 2 Alcohol dehydrogenase GroES-like domain LRR_8 PF13855.6 PSC70549.1 - 5.6e-06 26.0 6.3 6.4e-05 22.6 3.2 3.6 2 1 1 3 3 3 2 Leucine rich repeat Rab_bind PF16704.5 PSC70549.1 - 0.0017 18.4 0.0 0.81 9.8 0.0 2.5 2 0 0 2 2 2 2 Rab binding domain LRR_4 PF12799.7 PSC70549.1 - 0.0045 17.4 8.7 0.013 15.9 3.3 3.4 2 2 1 3 3 3 2 Leucine Rich repeats (2 copies) DUF2855 PF11017.8 PSC70549.1 - 0.034 13.9 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) FdhD-NarQ PF02634.15 PSC70549.1 - 0.19 11.4 0.4 13 5.3 0.1 2.6 3 0 0 3 3 3 0 FdhD/NarQ family DUF4123 PF13503.6 PSC70549.1 - 5.7 7.4 7.9 53 4.2 0.0 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4123) rve PF00665.26 PSC70550.1 - 8.7e-19 67.9 0.0 2e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC70550.1 - 0.0082 15.9 0.0 0.02 14.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain MMR_HSR1 PF01926.23 PSC70550.1 - 0.043 13.9 0.5 9.3 6.4 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase GCV_T PF01571.21 PSC70551.1 - 5.1e-34 117.8 0.1 6.9e-34 117.4 0.1 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain SoxG PF04268.12 PSC70551.1 - 0.017 15.3 0.0 0.089 12.9 0.0 2.2 1 1 1 2 2 2 0 Sarcosine oxidase, gamma subunit family GCV_T_C PF08669.11 PSC70551.1 - 0.042 13.8 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain GCV_T PF01571.21 PSC70552.1 - 5.2e-34 117.8 0.1 7e-34 117.4 0.1 1.2 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain SoxG PF04268.12 PSC70552.1 - 0.016 15.3 0.0 0.09 12.9 0.0 2.2 1 1 1 2 2 2 0 Sarcosine oxidase, gamma subunit family GCV_T_C PF08669.11 PSC70552.1 - 0.042 13.8 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 Glycine cleavage T-protein C-terminal barrel domain Methyltransf_24 PF13578.6 PSC70553.1 - 6.6e-06 27.1 0.0 1.1e-05 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Toxin_38 PF14866.6 PSC70553.1 - 0.011 16.0 2.4 0.018 15.3 2.4 1.3 1 0 0 1 1 1 0 Potassium channel toxin Methyltransf_24 PF13578.6 PSC70554.1 - 6.6e-06 27.1 0.0 1.1e-05 26.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Toxin_38 PF14866.6 PSC70554.1 - 0.011 16.0 2.4 0.018 15.3 2.4 1.3 1 0 0 1 1 1 0 Potassium channel toxin AMMECR1 PF01871.17 PSC70555.1 - 9.1e-45 152.2 0.0 1.2e-44 151.9 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 DUF5437 PF17505.2 PSC70555.1 - 0.055 13.5 0.1 0.14 12.2 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5437) GATase_2 PF00310.21 PSC70556.1 - 1.3e-162 541.3 0.0 1.7e-162 540.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Glu_synthase PF01645.17 PSC70556.1 - 4.8e-154 512.9 0.7 4e-153 509.9 0.7 2.2 2 0 0 2 2 2 1 Conserved region in glutamate synthase Glu_syn_central PF04898.14 PSC70556.1 - 1e-104 350.0 0.0 4.2e-102 341.4 0.0 2.3 2 0 0 2 2 2 2 Glutamate synthase central domain GXGXG PF01493.19 PSC70556.1 - 4.6e-70 235.1 7.9 4.6e-70 235.1 7.9 1.9 2 0 0 2 2 2 1 GXGXG motif UDG PF03167.19 PSC70556.1 - 1.6e-23 83.4 0.0 2.9e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily FMN_dh PF01070.18 PSC70556.1 - 3.1e-05 23.2 4.5 8.9e-05 21.7 3.9 2.0 2 0 0 2 2 2 1 FMN-dependent dehydrogenase Methyltransf_24 PF13578.6 PSC70557.1 - 4.5e-06 27.6 0.1 6.8e-06 27.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Chloroa_b-bind PF00504.21 PSC70558.1 - 1.9e-52 178.1 0.0 2.4e-52 177.7 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Pkinase PF00069.25 PSC70559.1 - 2.3e-07 30.5 0.0 3.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain HEAT PF02985.22 PSC70559.1 - 3.3e-06 26.9 0.3 1.8 9.0 0.1 4.9 5 0 0 5 5 5 2 HEAT repeat Cnd1 PF12717.7 PSC70559.1 - 1.7e-05 24.9 0.1 0.00011 22.3 0.0 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 PSC70559.1 - 0.13 10.8 0.0 1.8 7.0 0.1 1.8 1 1 1 2 2 2 0 Adaptin N terminal region DUF3819 PF12842.7 PSC70559.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3819) Peptidase_M27 PF01742.17 PSC70559.1 - 0.35 10.0 0.0 0.56 9.2 0.0 1.2 1 0 0 1 1 1 0 Clostridial neurotoxin zinc protease STELLO PF03385.17 PSC70560.1 - 2.6e-08 33.1 0.0 3.4e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 STELLO glycosyltransferases O-FucT PF10250.9 PSC70561.1 - 2.2e-18 67.1 0.0 7.8e-18 65.3 0.0 1.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_8 PF01501.20 PSC70561.1 - 0.0011 18.6 0.7 0.39 10.2 0.1 2.3 2 0 0 2 2 2 2 Glycosyl transferase family 8 GDI PF00996.18 PSC70562.1 - 6.5e-38 130.4 0.0 4.6e-37 127.6 0.0 1.9 1 1 0 1 1 1 1 GDP dissociation inhibitor FAD_oxidored PF12831.7 PSC70562.1 - 0.0026 17.2 0.6 0.01 15.2 0.6 2.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Glyco_transf_22 PF03901.17 PSC70563.1 - 3.7e-78 263.6 1.7 4.3e-78 263.4 1.7 1.0 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family LptF_LptG PF03739.14 PSC70563.1 - 0.075 11.9 0.1 0.075 11.9 0.1 2.5 3 0 0 3 3 3 0 Lipopolysaccharide export system permease LptF/LptG Nucleotid_trans PF03407.16 PSC70564.1 - 5.8e-11 42.8 0.0 7.4e-11 42.4 0.0 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Pro_isomerase PF00160.21 PSC70565.1 - 1.9e-40 138.7 0.0 3.1e-40 138.0 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 PSC70565.1 - 3.9e-15 55.4 0.0 8.2e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Spt20 PF12090.8 PSC70565.1 - 0.5 9.9 6.0 0.78 9.3 0.0 2.2 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 PSC70565.1 - 0.64 9.9 7.0 0.9 9.5 7.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_tranf_2_4 PF13704.6 PSC70566.1 - 2.8e-07 31.0 0.0 1.5e-06 28.6 0.0 2.2 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 PSC70566.1 - 3e-07 30.4 0.0 1.2e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase family 92 Na_sulph_symp PF00939.19 PSC70567.1 - 2.6e-128 429.0 35.9 3.4e-128 428.7 35.9 1.1 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 PSC70567.1 - 7.3e-12 45.1 35.2 1.6e-11 44.0 35.2 1.6 1 0 0 1 1 1 1 Citrate transporter Sulfotransfer_2 PF03567.14 PSC70567.1 - 0.0058 16.6 0.0 0.035 14.0 0.0 2.1 2 1 0 2 2 2 1 Sulfotransferase family UPF0051 PF01458.17 PSC70568.1 - 8.7e-66 221.7 0.1 1.1e-65 221.3 0.1 1.1 1 0 0 1 1 1 1 Uncharacterized protein family (UPF0051) TLC PF03219.14 PSC70569.1 - 7.8e-194 645.0 14.4 9.6e-194 644.7 14.4 1.0 1 0 0 1 1 1 1 TLC ATP/ADP transporter SSURE PF11966.8 PSC70569.1 - 0.18 11.6 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Fibronectin-binding repeat Aminotran_5 PF00266.19 PSC70570.1 - 4.7e-89 298.9 0.0 5.6e-89 298.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 PSC70570.1 - 1.6e-07 30.9 0.0 2e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 PSC70570.1 - 1.7e-05 24.3 0.0 3e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Pyridoxal_deC PF00282.19 PSC70570.1 - 0.0014 17.4 0.0 0.0029 16.4 0.0 1.5 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.20 PSC70570.1 - 0.12 10.9 0.0 0.19 10.2 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF3294 PF07957.11 PSC70571.1 - 0.081 12.7 0.0 0.17 11.7 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3294) Vps51 PF08700.11 PSC70573.1 - 4.6e-12 45.8 0.0 9.9e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 Dor1 PF04124.12 PSC70573.1 - 0.27 9.9 0.0 0.45 9.2 0.0 1.3 1 0 0 1 1 1 0 Dor1-like family SlyX PF04102.12 PSC70573.1 - 0.48 11.1 3.2 8.5 7.1 0.1 3.6 2 1 1 3 3 3 0 SlyX MMR_HSR1 PF01926.23 PSC70574.1 - 5.4e-16 58.7 0.1 2.1e-13 50.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 PSC70574.1 - 1.2e-05 24.9 0.0 0.00013 21.5 0.0 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PSC70574.1 - 2.6e-05 24.2 0.0 0.27 11.1 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase cobW PF02492.19 PSC70574.1 - 0.003 17.1 0.5 0.037 13.6 0.0 2.5 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 PSC70574.1 - 0.0094 15.0 0.5 0.021 13.8 0.1 1.7 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AF-4 PF05110.13 PSC70574.1 - 0.048 11.8 1.7 0.068 11.3 1.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein AAA_18 PF13238.6 PSC70574.1 - 0.083 13.4 0.2 2.8 8.5 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 PSC70574.1 - 1.6 9.0 7.0 0.44 10.9 0.1 2.9 1 1 1 3 3 3 0 AAA ATPase domain Rpp20 PF12328.8 PSC70574.1 - 2.4 8.1 4.9 0.48 10.4 0.1 2.2 3 0 0 3 3 3 0 Rpp20 subunit of nuclear RNase MRP and P RWP-RK PF02042.15 PSC70576.1 - 1.5e-17 63.3 0.0 4.8e-17 61.7 0.0 1.9 1 0 0 1 1 1 1 RWP-RK domain TPR_1 PF00515.28 PSC70576.1 - 2.2e-07 30.4 4.3 0.033 14.0 0.2 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PSC70576.1 - 2.4e-06 27.2 9.2 0.013 15.5 0.7 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat DUF2722 PF10846.8 PSC70576.1 - 0.00064 18.8 14.3 0.00064 18.8 14.3 2.4 4 0 0 4 4 4 1 Protein of unknown function (DUF2722) TPR_11 PF13414.6 PSC70576.1 - 0.00071 19.2 3.6 0.00071 19.2 0.3 2.5 2 1 1 3 3 3 1 TPR repeat TPR_17 PF13431.6 PSC70576.1 - 0.0031 17.8 2.5 0.97 10.0 0.6 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 PSC70576.1 - 0.0066 16.6 14.0 0.047 13.8 1.0 3.0 1 1 1 2 2 2 2 Tetratricopeptide repeat MecA PF05389.12 PSC70576.1 - 0.0086 15.7 0.8 0.016 14.9 0.8 1.4 1 0 0 1 1 1 1 Negative regulator of genetic competence (MecA) DUF3846 PF12957.7 PSC70576.1 - 0.015 15.6 0.0 0.033 14.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3846) Peptidase_C58 PF03543.14 PSC70576.1 - 0.044 13.5 15.9 0.017 14.8 13.0 1.8 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen Presenilin PF01080.17 PSC70576.1 - 0.06 12.1 2.9 0.12 11.1 2.9 1.4 1 0 0 1 1 1 0 Presenilin DDHD PF02862.17 PSC70576.1 - 0.13 12.4 3.7 0.094 12.9 1.5 1.9 2 0 0 2 2 2 0 DDHD domain DUF4770 PF15994.5 PSC70576.1 - 0.37 11.0 8.5 1.2 9.3 8.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) GREB1 PF15782.5 PSC70576.1 - 0.47 7.5 4.5 0.64 7.1 4.5 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Band_3_cyto PF07565.13 PSC70576.1 - 0.5 10.1 5.2 0.3 10.8 2.1 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain eIF-3_zeta PF05091.12 PSC70576.1 - 1.1 8.1 10.2 2.1 7.2 10.2 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TERB2 PF15101.6 PSC70576.1 - 1.9 8.5 14.8 5.4 7.0 14.8 1.7 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CPSF100_C PF13299.6 PSC70576.1 - 2 8.6 7.3 0.72 10.0 4.1 2.0 2 0 0 2 2 1 0 Cleavage and polyadenylation factor 2 C-terminal EPL1 PF10513.9 PSC70576.1 - 2 8.8 7.8 0.39 11.1 3.8 1.8 2 0 0 2 2 1 0 Enhancer of polycomb-like Peroxin-13_N PF04088.13 PSC70576.1 - 2.1 8.6 5.3 5.8 7.2 5.3 1.7 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Neur_chan_memb PF02932.16 PSC70576.1 - 2.2 8.3 3.6 1.4 8.9 1.6 1.7 2 0 0 2 2 1 0 Neurotransmitter-gated ion-channel transmembrane region SpoIIP PF07454.11 PSC70576.1 - 3.3 7.1 8.5 6 6.2 8.5 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Het-C PF07217.11 PSC70576.1 - 7.6 4.9 7.8 14 4.1 7.4 1.5 2 0 0 2 2 2 0 Heterokaryon incompatibility protein Het-C DUF563 PF04577.14 PSC70577.1 - 8e-07 29.4 0.0 1.3e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF563) O-FucT PF10250.9 PSC70579.1 - 3.3e-07 30.3 0.0 1.3e-05 25.1 0.0 2.5 2 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase T2SSM PF04612.12 PSC70579.1 - 5.8 6.9 8.3 0.47 10.5 0.1 2.4 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M WD40 PF00400.32 PSC70580.1 - 9.9e-07 29.4 10.2 0.00022 21.9 0.2 5.0 5 0 0 5 5 5 3 WD domain, G-beta repeat WD40 PF00400.32 PSC70581.1 - 5.6e-59 194.7 26.3 3e-07 31.0 0.0 12.0 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.11 PSC70581.1 - 5.8e-41 139.7 0.0 9.3e-41 139.0 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain SRP14 PF02290.15 PSC70581.1 - 8.2e-24 83.8 0.2 1.6e-23 82.9 0.2 1.5 1 0 0 1 1 1 1 Signal recognition particle 14kD protein ANAPC4_WD40 PF12894.7 PSC70581.1 - 2e-16 60.1 0.6 0.05 13.9 0.0 8.3 4 3 4 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PSC70581.1 - 2.5e-06 26.4 10.7 0.36 9.4 0.0 7.3 5 3 3 9 9 9 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 PSC70581.1 - 0.0012 17.5 0.0 0.019 13.5 0.0 2.9 4 0 0 4 4 4 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 PSC70581.1 - 0.002 17.1 1.4 11 4.8 0.0 4.9 3 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 PSC70581.1 - 0.041 13.2 0.0 0.37 10.1 0.0 2.6 4 0 0 4 4 4 0 WD40-like domain DUF2981 PF11200.8 PSC70581.1 - 3.2 7.4 9.0 5.1 6.7 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) TFIIF_alpha PF05793.12 PSC70581.1 - 7.5 5.0 8.5 11 4.4 8.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) WD40 PF00400.32 PSC70582.1 - 4.9e-59 194.9 26.3 3e-07 31.0 0.0 12.0 12 0 0 12 12 12 10 WD domain, G-beta repeat Utp13 PF08625.11 PSC70582.1 - 5.7e-41 139.7 0.0 9.2e-41 139.1 0.0 1.3 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain SRP14 PF02290.15 PSC70582.1 - 8.1e-24 83.8 0.2 1.5e-23 82.9 0.2 1.5 1 0 0 1 1 1 1 Signal recognition particle 14kD protein ANAPC4_WD40 PF12894.7 PSC70582.1 - 1.8e-16 60.2 0.6 0.05 13.9 0.0 8.3 4 3 5 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PSC70582.1 - 2.3e-06 26.5 10.7 0.36 9.4 0.0 7.4 5 3 3 9 9 9 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 PSC70582.1 - 0.0011 17.6 0.0 0.019 13.5 0.0 2.9 4 0 0 4 4 4 1 Cytochrome D1 heme domain Ge1_WD40 PF16529.5 PSC70582.1 - 0.0019 17.2 1.4 12 4.7 0.0 4.9 3 2 2 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 PSC70582.1 - 0.04 13.2 0.0 0.37 10.1 0.0 2.6 4 0 0 4 4 4 0 WD40-like domain DUF2981 PF11200.8 PSC70582.1 - 3.2 7.4 9.0 5.1 6.8 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) TFIIF_alpha PF05793.12 PSC70582.1 - 7.3 5.0 8.5 11 4.4 8.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) UPF0113 PF03657.13 PSC70583.1 - 2.5e-24 85.3 0.0 4.1e-24 84.6 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain UPF0113_N PF17833.1 PSC70583.1 - 1.8e-14 54.0 0.1 2.8e-14 53.4 0.1 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain DUF3755 PF12579.8 PSC70584.1 - 2e-10 40.1 0.2 2e-10 40.1 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3755) Myb_DNA-binding PF00249.31 PSC70584.1 - 0.0021 18.2 0.0 0.0041 17.3 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3755 PF12579.8 PSC70585.1 - 2e-10 40.1 0.2 2e-10 40.1 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3755) Myb_DNA-binding PF00249.31 PSC70585.1 - 0.0021 18.2 0.0 0.0041 17.3 0.0 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Ribonucleas_3_3 PF14622.6 PSC70586.1 - 4.5e-16 59.2 0.0 6e-16 58.8 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 PSC70586.1 - 1.7e-11 44.7 0.0 3e-11 43.9 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease III domain KH_1 PF00013.29 PSC70587.1 - 8.3e-07 28.7 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 KH domain NAM-associated PF14303.6 PSC70587.1 - 1.8 9.3 3.1 3.8 8.2 3.1 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain KH_1 PF00013.29 PSC70588.1 - 8.3e-07 28.7 0.0 1.4e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 KH domain NAM-associated PF14303.6 PSC70588.1 - 1.8 9.3 3.1 3.8 8.2 3.1 1.5 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain zf-LSD1 PF06943.12 PSC70589.1 - 2.8e-29 100.6 33.2 3.8e-12 45.8 6.0 3.3 3 0 0 3 3 3 3 LSD1 zinc finger zinc_ribbon_4 PF13717.6 PSC70589.1 - 0.0029 17.5 15.1 0.94 9.4 0.1 4.8 5 0 0 5 5 5 3 zinc-ribbon domain Auto_anti-p27 PF06677.12 PSC70589.1 - 0.0052 16.9 0.6 0.0052 16.9 0.6 3.3 3 1 1 4 4 4 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-C3HC4_3 PF13920.6 PSC70589.1 - 0.009 15.8 2.3 0.009 15.8 2.3 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Mu-like_Com PF10122.9 PSC70589.1 - 0.011 15.1 7.6 2.6 7.6 0.2 3.3 3 0 0 3 3 3 0 Mu-like prophage protein Com RNA_POL_M_15KD PF02150.16 PSC70589.1 - 0.014 15.2 8.6 0.56 10.1 0.4 3.5 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit IBR PF01485.21 PSC70589.1 - 0.04 14.1 13.4 0.59 10.4 0.3 3.3 3 0 0 3 3 3 0 IBR domain, a half RING-finger domain TackOD1 PF18551.1 PSC70589.1 - 0.11 12.2 9.0 3 7.5 0.1 2.3 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 PriA_CRR PF18319.1 PSC70589.1 - 0.11 12.5 9.3 0.35 10.9 0.1 3.3 3 0 0 3 3 3 0 PriA DNA helicase Cys-rich region (CRR) domain C1_1 PF00130.22 PSC70589.1 - 0.47 10.4 14.2 1.9 8.4 0.5 3.2 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Ribosomal_S27e PF01667.17 PSC70589.1 - 1.2 8.9 22.9 4 7.2 0.2 4.2 3 1 1 4 4 4 0 Ribosomal protein S27 zinc_ribbon_6 PF14599.6 PSC70589.1 - 1.2 9.2 10.0 4.3 7.4 1.3 3.0 2 1 1 3 3 3 0 Zinc-ribbon Zn_Tnp_IS1595 PF12760.7 PSC70589.1 - 2.9 7.9 12.2 17 5.5 4.9 3.3 2 1 0 2 2 2 0 Transposase zinc-ribbon domain RecR PF02132.15 PSC70589.1 - 3 7.5 15.1 0.59 9.8 0.8 3.7 4 0 0 4 4 4 0 RecR protein zf-Sec23_Sec24 PF04810.15 PSC70589.1 - 3.4 7.8 18.4 8.3 6.6 0.4 4.6 4 1 0 4 4 4 0 Sec23/Sec24 zinc finger Ribosomal_L37e PF01907.19 PSC70589.1 - 7.7 6.8 10.8 0.53 10.5 2.1 2.9 2 1 1 3 3 3 0 Ribosomal protein L37e PSII_BNR PF14870.6 PSC70590.1 - 1.3e-124 415.4 0.1 1.6e-124 415.1 0.1 1.0 1 0 0 1 1 1 1 Photosynthesis system II assembly factor YCF48 Sortilin-Vps10 PF15902.5 PSC70590.1 - 6.3e-08 31.8 0.0 0.0012 17.7 0.0 3.5 2 1 1 3 3 3 3 Sortilin, neurotensin receptor 3, BNR PF02012.20 PSC70590.1 - 7.2e-08 31.3 6.1 0.3 11.2 0.0 4.9 4 0 0 4 4 4 3 BNR/Asp-box repeat GDP_Man_Dehyd PF16363.5 PSC70591.1 - 5.4e-68 229.8 0.0 6.3e-68 229.6 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PSC70591.1 - 7.8e-55 185.9 0.1 9.8e-55 185.6 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 PSC70591.1 - 8.9e-22 77.6 0.1 3.2e-20 72.4 0.1 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 PSC70591.1 - 1.5e-19 70.0 0.1 2.2e-19 69.5 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 PSC70591.1 - 1.2e-17 64.0 0.1 1.1e-16 60.9 0.1 2.0 1 1 0 1 1 1 1 Male sterility protein RmlD_sub_bind PF04321.17 PSC70591.1 - 2.5e-16 59.7 0.0 3.5e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 PSC70591.1 - 0.00058 19.8 0.0 0.00091 19.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding adh_short PF00106.25 PSC70591.1 - 0.003 17.0 0.4 1 8.8 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 PSC70591.1 - 0.05 13.9 0.0 0.088 13.1 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Pkinase_Tyr PF07714.17 PSC70592.1 - 7.7e-40 136.8 0.0 9.5e-35 120.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PSC70592.1 - 7.2e-35 120.6 0.0 1.1e-34 120.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GAF PF01590.26 PSC70592.1 - 2.2e-05 25.1 0.0 5.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 GAF domain Kdo PF06293.14 PSC70592.1 - 0.0045 16.4 0.0 0.0077 15.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PSC70592.1 - 0.0083 14.9 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PSC70592.1 - 0.039 13.9 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family PEPcase PF00311.17 PSC70593.1 - 1.3e-275 916.5 0.0 1.6e-275 916.2 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 PSC70593.1 - 0.00091 17.8 0.0 0.0018 16.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase FTA4 PF13093.6 PSC70593.1 - 0.016 15.1 1.0 0.034 14.0 1.0 1.6 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 CM_1 PF07736.11 PSC70593.1 - 0.044 14.2 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 Chorismate mutase type I DUF383 PF04063.14 PSC70594.1 - 3e-20 72.7 0.1 1.1e-19 70.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF383) GLTSCR1 PF15249.6 PSC70594.1 - 4.8e-07 30.1 15.6 3.4e-05 24.2 15.6 2.5 1 1 0 1 1 1 1 Conserved region of unknown function on GLTSCR protein CCDC84 PF14968.6 PSC70594.1 - 0.38 10.3 10.6 0.55 9.8 10.6 1.2 1 0 0 1 1 1 0 Coiled coil protein 84 SOBP PF15279.6 PSC70594.1 - 4.7 7.7 13.7 6.7 7.2 13.7 1.3 1 0 0 1 1 1 0 Sine oculis-binding protein TFIIA PF03153.13 PSC70594.1 - 7.8 6.4 44.7 11 5.8 44.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF572 PF04502.13 PSC70594.1 - 8.7 5.9 11.9 12 5.4 11.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Med26_C PF15693.5 PSC70594.1 - 9.1 6.4 12.8 17 5.5 12.8 1.4 1 0 0 1 1 1 0 Mediator complex subunit 26 C-terminal PH PF00169.29 PSC70595.1 - 1.9e-13 50.8 0.0 3.4e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 PH domain WW PF00397.26 PSC70595.1 - 6.1e-09 35.8 3.3 1.5e-08 34.6 3.3 1.7 1 0 0 1 1 1 1 WW domain PH_11 PF15413.6 PSC70595.1 - 0.0078 16.6 0.9 0.019 15.4 0.9 1.7 1 1 0 1 1 1 1 Pleckstrin homology domain Galactosyl_T PF01762.21 PSC70596.1 - 0.23 11.3 0.0 0.34 10.7 0.0 1.2 1 0 0 1 1 1 0 Galactosyltransferase Galactosyl_T PF01762.21 PSC70597.1 - 0.23 11.3 0.0 0.34 10.7 0.0 1.2 1 0 0 1 1 1 0 Galactosyltransferase Ribosomal_L35p PF01632.19 PSC70598.1 - 4e-09 36.8 2.5 8.8e-09 35.7 2.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L35 Lyase_1 PF00206.20 PSC70599.1 - 4.6e-99 331.7 0.0 6.8e-99 331.2 0.0 1.3 1 0 0 1 1 1 1 Lyase PAN_1 PF00024.26 PSC70599.1 - 9.5e-25 86.4 0.5 9.5e-05 22.3 0.0 5.4 5 0 0 5 5 5 5 PAN domain ASL_C2 PF14698.6 PSC70599.1 - 2e-23 82.9 0.1 6e-23 81.4 0.1 1.9 1 0 0 1 1 1 1 Argininosuccinate lyase C-terminal PAN_4 PF14295.6 PSC70599.1 - 8.1e-22 76.9 25.5 5.9e-05 22.9 1.1 5.6 5 0 0 5 5 5 5 PAN domain Nucleotid_trans PF03407.16 PSC70599.1 - 2.3e-10 40.8 0.0 4.3e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase O-FucT PF10250.9 PSC70599.1 - 8.1e-09 35.6 0.0 1.6e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase PAN_2 PF08276.11 PSC70599.1 - 0.0005 20.1 27.1 0.45 10.7 0.4 5.0 5 0 0 5 5 5 4 PAN-like domain AdoMetDC_leader PF08132.11 PSC70599.1 - 0.056 13.4 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 S-adenosyl-l-methionine decarboxylase leader peptide O-FucT PF10250.9 PSC70600.1 - 5.5e-10 39.5 0.1 2.8e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase Sulfotransfer_2 PF03567.14 PSC70601.1 - 0.12 12.3 0.0 0.26 11.2 0.0 1.5 1 1 0 1 1 1 0 Sulfotransferase family ATP-grasp PF02222.22 PSC70602.1 - 0.1 12.1 0.3 0.25 10.9 0.3 1.6 1 0 0 1 1 1 0 ATP-grasp domain KH_1 PF00013.29 PSC70603.1 - 1.4e-25 88.9 0.0 6e-12 45.2 0.0 2.6 3 0 0 3 3 3 2 KH domain KH_2 PF07650.17 PSC70603.1 - 0.00024 20.9 0.0 0.21 11.4 0.0 2.2 2 0 0 2 2 2 2 KH domain KH_4 PF13083.6 PSC70603.1 - 0.0092 15.8 0.0 6.9 6.6 0.0 2.5 2 0 0 2 2 2 2 KH domain PAC3 PF10178.9 PSC70604.1 - 1.1e-13 51.1 0.0 1.6e-13 50.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome assembly chaperone 3 Sulfotransfer_3 PF13469.6 PSC70605.1 - 0.002 18.5 0.3 0.0089 16.4 0.0 2.0 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PSC70605.1 - 0.0028 17.2 0.0 0.0048 16.4 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase domain TAL_FSA PF00923.19 PSC70606.1 - 3.4e-40 138.2 0.0 4.9e-40 137.7 0.0 1.2 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase DHQ_synthase PF01761.20 PSC70608.1 - 1.1e-106 355.9 0.0 1.4e-106 355.5 0.0 1.1 1 0 0 1 1 1 1 3-dehydroquinate synthase Fe-ADH_2 PF13685.6 PSC70608.1 - 1.5e-12 47.8 0.1 3.5e-11 43.3 0.1 2.1 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH PF00465.19 PSC70608.1 - 7e-09 35.0 0.6 1.1e-08 34.3 0.6 1.4 1 1 0 1 1 1 1 Iron-containing alcohol dehydrogenase Glyco_trans_4_4 PF13579.6 PSC70608.1 - 0.14 12.6 6.3 0.37 11.2 6.3 1.7 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Cpn60_TCP1 PF00118.24 PSC70609.1 - 2.2e-99 333.3 17.8 3.8e-99 332.5 17.8 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Bac_surface_Ag PF01103.23 PSC70609.1 - 1.3e-15 57.8 0.6 1.8e-15 57.2 0.6 1.2 1 0 0 1 1 1 1 Surface antigen POTRA PF07244.15 PSC70609.1 - 0.00018 22.0 0.0 0.65 10.6 0.0 3.8 3 0 0 3 3 3 1 Surface antigen variable number repeat POTRA_2 PF08479.11 PSC70609.1 - 0.035 13.9 0.0 0.21 11.4 0.0 2.4 1 0 0 1 1 1 0 POTRA domain, ShlB-type CENP-B_dimeris PF09026.10 PSC70609.1 - 0.32 11.4 11.4 0.7 10.3 11.4 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Roughex PF06020.11 PSC70609.1 - 0.61 9.1 2.6 1 8.4 2.6 1.2 1 0 0 1 1 1 0 Drosophila roughex protein NOA36 PF06524.12 PSC70609.1 - 4.3 6.6 7.5 6.7 5.9 7.5 1.2 1 0 0 1 1 1 0 NOA36 protein rve PF00665.26 PSC70610.1 - 1.3e-18 67.3 0.0 2.7e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain ADH_zinc_N_2 PF13602.6 PSC70610.1 - 1.9e-17 64.6 0.2 5e-17 63.2 0.2 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PSC70610.1 - 0.00063 19.6 1.9 0.0026 17.6 0.3 2.7 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain rve_3 PF13683.6 PSC70610.1 - 0.01 15.6 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Rab_bind PF16704.5 PSC70610.1 - 0.1 12.7 0.0 0.24 11.4 0.0 1.6 1 0 0 1 1 1 0 Rab binding domain Lactate_perm PF02652.14 PSC70611.1 - 1.6e-47 162.4 21.3 1.1e-25 90.4 0.3 2.0 2 0 0 2 2 2 2 L-lactate permease SPC22 PF04573.12 PSC70612.1 - 1.4e-35 122.3 0.0 1.7e-35 122.0 0.0 1.1 1 0 0 1 1 1 1 Signal peptidase subunit DUF4462 PF14692.6 PSC70612.1 - 4.2 6.9 5.3 9.7 5.8 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4462) FtsJ PF01728.19 PSC70613.1 - 6.3e-11 42.7 0.0 1.1e-10 41.9 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Sel1 PF08238.12 PSC70613.1 - 5.3e-05 23.7 0.8 0.00017 22.2 0.8 2.0 1 0 0 1 1 1 1 Sel1 repeat Methyltransf_23 PF13489.6 PSC70613.1 - 0.086 12.7 0.0 0.89 9.4 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain F_actin_bind PF08919.10 PSC70614.1 - 0.026 14.6 0.2 0.089 12.9 0.2 1.9 1 0 0 1 1 1 0 F-actin binding AAA_22 PF13401.6 PSC70614.1 - 0.043 14.1 1.7 0.094 13.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain TniB PF05621.11 PSC70614.1 - 0.044 13.2 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein AAA_29 PF13555.6 PSC70614.1 - 0.079 12.7 0.0 0.24 11.2 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain Phage_lysozyme PF00959.19 PSC70614.1 - 0.19 12.2 0.4 2.2 8.8 0.1 2.5 2 0 0 2 2 2 0 Phage lysozyme BAR_3 PF16746.5 PSC70614.1 - 0.42 10.3 3.6 0.86 9.3 3.6 1.4 1 0 0 1 1 1 0 BAR domain of APPL family Spc7 PF08317.11 PSC70614.1 - 1.3 7.9 10.5 2.4 6.9 10.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein RabGAP-TBC PF00566.18 PSC70615.1 - 5.6e-47 160.2 0.1 3.2e-46 157.7 0.0 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Sigma70_r2 PF04542.14 PSC70615.1 - 0.54 10.1 0.0 0.54 10.1 0.0 2.8 4 0 0 4 4 4 0 Sigma-70 region 2 PTCB-BRCT PF12738.7 PSC70616.1 - 4.7e-12 45.7 0.0 7.8e-12 45.0 0.0 1.4 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.26 PSC70616.1 - 0.00013 22.2 0.0 0.00025 21.4 0.0 1.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain Pkinase PF00069.25 PSC70617.1 - 3.1e-64 216.9 0.0 4.2e-64 216.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC70617.1 - 3.9e-19 68.9 0.0 6e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase O-FucT PF10250.9 PSC70617.1 - 5.9e-12 45.9 0.0 3.9e-11 43.2 0.0 2.1 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase APH PF01636.23 PSC70617.1 - 4.9e-08 33.2 0.0 4.2e-05 23.6 0.1 3.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PSC70617.1 - 0.013 14.3 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 PSC70617.1 - 0.015 14.6 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 PSC70617.1 - 0.041 13.5 0.1 0.077 12.6 0.1 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Costars PF14705.6 PSC70617.1 - 0.071 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Costars Pkinase PF00069.25 PSC70618.1 - 1.5e-48 165.5 0.0 7.4e-48 163.2 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain cNMP_binding PF00027.29 PSC70618.1 - 6.3e-40 135.2 0.6 4.6e-21 74.7 0.1 2.5 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Pkinase_Tyr PF07714.17 PSC70618.1 - 2.1e-16 60.0 0.0 1.6e-15 57.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PSC70618.1 - 0.0089 16.0 1.0 2.2 8.2 0.0 2.9 2 1 0 2 2 2 1 Phosphotransferase enzyme family Exostosin PF03016.15 PSC70619.1 - 1.3e-16 60.7 0.0 1.9e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Exostosin family Papo_T_antigen PF02380.15 PSC70619.1 - 0.0004 20.5 2.7 0.15 12.3 0.7 2.3 2 0 0 2 2 2 2 T-antigen specific domain Kelch_6 PF13964.6 PSC70620.1 - 2.1e-22 78.6 1.3 0.00011 22.3 0.0 5.4 3 1 2 5 5 5 3 Kelch motif Kelch_1 PF01344.25 PSC70620.1 - 1.4e-19 69.4 1.3 0.00012 21.5 0.0 5.5 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 PSC70620.1 - 2.3e-11 43.7 5.0 0.02 15.2 0.2 5.7 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.6 PSC70620.1 - 2.6e-10 40.1 3.3 0.6 10.2 0.0 6.1 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_2 PF07646.15 PSC70620.1 - 8e-10 38.3 0.2 0.24 11.4 0.0 5.1 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 PSC70620.1 - 2.8e-06 27.2 4.1 0.44 10.6 0.1 4.4 4 0 0 4 4 4 2 Kelch motif SAP PF02037.27 PSC70620.1 - 0.0017 18.1 0.1 0.003 17.3 0.1 1.5 1 0 0 1 1 1 1 SAP domain WGG PF10273.9 PSC70621.1 - 2e-22 79.6 0.2 3.4e-22 78.9 0.2 1.4 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 DUF1987 PF09345.10 PSC70621.1 - 0.07 12.8 0.2 0.13 12.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1987) Ribosomal_60s PF00428.19 PSC70621.1 - 0.1 13.2 9.9 0.23 12.1 9.9 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Shadoo PF14999.6 PSC70621.1 - 0.24 11.5 5.8 0.44 10.7 5.8 1.4 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective CENP-B_dimeris PF09026.10 PSC70621.1 - 0.62 10.5 12.0 1.2 9.6 12.0 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain DUF3591 PF12157.8 PSC70622.1 - 3.7e-72 243.4 0.0 5.8e-72 242.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 PSC70622.1 - 4e-10 39.6 0.0 9.4e-10 38.4 0.0 1.5 1 0 0 1 1 1 1 Bromodomain TBP-binding PF09247.11 PSC70622.1 - 1.8e-09 37.7 0.1 4.6e-09 36.4 0.1 1.6 1 0 0 1 1 1 1 TATA box-binding protein binding Epimerase_2 PF02350.19 PSC70622.1 - 0.048 12.5 0.5 0.076 11.9 0.5 1.2 1 0 0 1 1 1 0 UDP-N-acetylglucosamine 2-epimerase DUF2293 PF10056.9 PSC70622.1 - 0.54 10.5 2.7 39 4.6 0.1 3.8 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2293) ANAPC4_WD40 PF12894.7 PSC70623.1 - 8.2e-07 29.2 0.8 0.24 11.7 0.0 4.3 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PSC70623.1 - 0.00042 21.1 0.3 5.9 7.9 0.1 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF3223 PF11523.8 PSC70624.1 - 1.8e-05 25.5 0.0 3.9e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3223) CDK2AP PF09806.9 PSC70624.1 - 0.19 11.8 4.1 0.29 11.2 4.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein DUF4407 PF14362.6 PSC70624.1 - 7 5.9 7.7 9.5 5.5 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Sulfotransfer_2 PF03567.14 PSC70625.1 - 0.0084 16.0 0.1 0.023 14.6 0.1 1.7 1 1 0 1 1 1 1 Sulfotransferase family GDP_Man_Dehyd PF16363.5 PSC70626.1 - 1.9e-153 510.7 0.0 2.2e-153 510.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PSC70626.1 - 1.4e-71 240.8 0.1 1.7e-71 240.5 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 PSC70626.1 - 0.00027 20.1 0.0 0.00044 19.4 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 PSC70626.1 - 0.028 13.6 0.0 0.039 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein ATP-synt PF00231.19 PSC70627.1 - 1.7e-60 205.1 2.0 2.3e-60 204.7 2.0 1.1 1 0 0 1 1 1 1 ATP synthase TPR_1 PF00515.28 PSC70628.1 - 3.6e-29 99.4 21.9 7.6e-07 28.7 0.0 8.8 8 1 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 PSC70628.1 - 3e-27 92.5 24.7 6.9e-05 22.7 0.3 9.5 10 0 0 10 10 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 PSC70628.1 - 1.8e-25 87.0 14.7 7.2e-05 22.7 0.0 9.2 9 1 1 10 10 9 5 Tetratricopeptide repeat TPR_14 PF13428.6 PSC70628.1 - 3.3e-20 71.0 39.5 0.00012 22.6 0.0 10.3 8 3 3 11 11 10 5 Tetratricopeptide repeat ANAPC8 PF04049.13 PSC70628.1 - 5.8e-20 71.8 4.4 4.5e-12 46.2 0.1 2.9 3 0 0 3 3 2 2 Anaphase promoting complex subunit 8 / Cdc23 TPR_11 PF13414.6 PSC70628.1 - 4.8e-16 58.2 3.7 1.6e-06 27.7 0.2 5.5 4 1 1 5 5 5 3 TPR repeat TPR_7 PF13176.6 PSC70628.1 - 1.1e-15 56.3 23.0 0.0011 18.9 0.2 7.9 7 1 1 8 8 7 5 Tetratricopeptide repeat TPR_19 PF14559.6 PSC70628.1 - 1.3e-14 54.4 22.9 4.7e-06 27.0 0.5 7.5 6 3 2 8 8 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 PSC70628.1 - 4.5e-13 49.6 42.4 3.1e-07 30.9 1.2 8.5 7 1 2 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 PSC70628.1 - 5.8e-13 48.9 35.4 0.0006 20.1 4.9 7.9 4 1 2 7 7 6 5 Tetratricopeptide repeat TPR_17 PF13431.6 PSC70628.1 - 6.4e-10 38.7 6.5 0.16 12.4 0.0 7.9 6 1 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 PSC70628.1 - 4.6e-09 36.3 22.5 0.013 16.0 0.1 9.7 9 1 1 10 10 10 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PSC70628.1 - 1.1e-07 31.9 22.8 0.00071 19.8 0.5 7.3 4 2 4 8 8 8 2 Anaphase-promoting complex, cyclosome, subunit 3 ChAPs PF09295.10 PSC70628.1 - 5.2e-06 25.7 0.2 0.27 10.2 0.0 3.8 2 1 2 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) Fis1_TPR_C PF14853.6 PSC70628.1 - 3.3e-05 23.9 0.1 0.007 16.4 0.0 3.1 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.6 PSC70628.1 - 0.00024 20.9 39.6 0.38 10.7 0.2 8.8 10 0 0 10 10 10 4 Tetratricopeptide repeat NARP1 PF12569.8 PSC70628.1 - 0.00052 19.1 2.1 0.015 14.2 0.2 2.8 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_9 PF13371.6 PSC70628.1 - 0.011 15.8 0.3 0.011 15.8 0.3 5.9 6 2 0 7 7 6 0 Tetratricopeptide repeat Coatomer_E PF04733.14 PSC70628.1 - 0.044 13.2 1.6 0.092 12.1 0.1 2.0 2 0 0 2 2 2 0 Coatomer epsilon subunit SRP_TPR_like PF17004.5 PSC70628.1 - 0.063 13.3 1.0 0.18 11.9 0.0 2.2 3 0 0 3 3 3 0 Putative TPR-like repeat PPR PF01535.20 PSC70628.1 - 0.12 12.7 0.1 26 5.3 0.0 3.5 3 0 0 3 3 3 0 PPR repeat PGP_phosphatase PF09419.10 PSC70629.1 - 9.4e-38 129.5 0.0 1.2e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 PSC70629.1 - 9.5e-06 25.6 0.0 1.9e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 PSC70629.1 - 0.055 13.5 0.0 0.13 12.3 0.0 1.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PSC70629.1 - 0.16 12.2 0.0 1.3 9.3 0.0 2.1 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase NIF PF03031.18 PSC70630.1 - 4.4e-32 111.0 0.0 1.3e-31 109.5 0.0 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Put_Phosphatase PF06888.12 PSC70630.1 - 5.6e-31 107.7 0.0 1.1e-18 67.5 0.0 2.3 2 0 0 2 2 2 2 Putative Phosphatase SPX PF03105.19 PSC70630.1 - 1.4e-07 31.8 14.5 2.9e-05 24.2 0.1 4.0 2 1 2 4 4 4 2 SPX domain HAD PF12710.7 PSC70630.1 - 2.2e-07 31.4 5.1 0.00012 22.6 0.0 5.0 5 0 0 5 5 5 1 haloacid dehalogenase-like hydrolase zf-RING_UBOX PF13445.6 PSC70630.1 - 1.6e-05 24.8 2.5 1.7e-05 24.7 0.3 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PSC70630.1 - 1.7e-05 24.6 0.8 1.7e-05 24.6 0.8 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PSC70630.1 - 1.8e-05 24.8 1.0 1.8e-05 24.8 1.0 2.6 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 PSC70630.1 - 2.3e-05 24.2 0.8 2.3e-05 24.2 0.8 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC70630.1 - 8.5e-05 22.3 0.4 8.5e-05 22.3 0.4 2.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC70630.1 - 9.2e-05 22.7 1.0 9.2e-05 22.7 1.0 3.2 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 PSC70630.1 - 0.0017 18.2 0.4 0.0017 18.2 0.4 2.7 3 0 0 3 3 3 1 zinc-RING finger domain DUF1644 PF07800.12 PSC70630.1 - 0.0022 18.1 1.3 0.0045 17.1 1.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1644) Elf1 PF05129.13 PSC70630.1 - 0.2 11.7 0.9 1.9 8.6 0.4 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-RING_6 PF14835.6 PSC70630.1 - 0.3 11.0 3.0 0.57 10.1 0.3 2.7 3 0 0 3 3 3 0 zf-RING of BARD1-type protein TFIIA PF03153.13 PSC70630.1 - 1 9.2 6.4 1.8 8.4 6.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2703 PF10865.8 PSC70631.1 - 0.14 12.3 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2703) tRNA-synt_1 PF00133.22 PSC70632.1 - 2.1e-193 643.9 0.0 2.6e-193 643.6 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PSC70632.1 - 4.8e-30 104.5 0.0 8.5e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 PSC70632.1 - 4.4e-21 75.1 0.0 1.9e-12 46.7 0.0 3.3 3 0 0 3 3 3 3 tRNA synthetases class I (M) zf-FPG_IleRS PF06827.14 PSC70632.1 - 3e-09 36.6 2.2 5.6e-09 35.7 2.2 1.5 1 0 0 1 1 1 1 Zinc finger found in FPG and IleRS tRNA-synt_1_2 PF13603.6 PSC70632.1 - 0.00013 21.6 0.0 0.00024 20.7 0.0 1.3 1 0 0 1 1 1 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 PSC70632.1 - 0.0033 16.8 0.0 0.37 10.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain NPCBM_assoc PF10633.9 PSC70632.1 - 0.049 13.9 0.1 4.8 7.5 0.0 2.9 2 0 0 2 2 2 0 NPCBM-associated, NEW3 domain of alpha-galactosidase DctQ PF04290.12 PSC70633.1 - 0.05 13.5 0.2 0.087 12.7 0.2 1.3 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component NAD_Gly3P_dh_C PF07479.14 PSC70634.1 - 2.1e-46 157.7 1.4 3.9e-46 156.9 1.4 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 PSC70634.1 - 6.1e-44 149.8 0.0 1.2e-43 148.7 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 PSC70634.1 - 5e-09 36.0 0.0 8.7e-09 35.2 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 PSC70634.1 - 5.3e-06 26.9 0.3 4.1e-05 24.1 0.0 2.6 3 0 0 3 3 3 1 NADP oxidoreductase coenzyme F420-dependent Sacchrp_dh_NADP PF03435.18 PSC70634.1 - 0.0079 16.5 0.3 0.055 13.7 0.0 2.3 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 PSC70634.1 - 0.029 13.6 0.0 0.056 12.7 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PSC70634.1 - 0.032 13.8 0.0 0.14 11.7 0.0 1.9 2 1 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 PSC70634.1 - 0.066 13.7 0.0 0.36 11.3 0.0 2.2 1 1 0 1 1 1 0 Putative NAD(P)-binding CCB2_CCB4 PF11152.8 PSC70636.1 - 3.1e-43 147.4 0.7 4.9e-43 146.7 0.7 1.3 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B, CCB2/CCB4 Ribosomal_L21p PF00829.21 PSC70636.1 - 1.1e-30 105.9 0.0 1.7e-30 105.3 0.0 1.3 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein MMR_HSR1 PF01926.23 PSC70640.1 - 2e-50 169.6 0.0 2e-24 85.9 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.6 PSC70640.1 - 1.3e-28 99.1 0.0 2.4e-28 98.2 0.0 1.5 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.18 PSC70640.1 - 2.4e-22 79.1 0.0 2e-10 40.4 0.0 2.9 2 1 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.27 PSC70640.1 - 1e-15 57.8 0.1 3e-09 36.7 0.2 5.0 5 1 0 5 5 5 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 PSC70640.1 - 4.5e-12 45.7 0.0 3.6e-06 26.5 0.0 2.5 2 0 0 2 2 2 2 AIG1 family Complex1_LYR PF05347.15 PSC70640.1 - 1.6e-11 44.1 0.1 1.6e-11 44.1 0.1 2.0 2 0 0 2 2 2 1 Complex 1 protein (LYR family) RsgA_GTPase PF03193.16 PSC70640.1 - 2e-09 37.6 0.0 0.063 13.2 0.0 4.9 5 0 0 5 5 5 3 RsgA GTPase Dynamin_N PF00350.23 PSC70640.1 - 3.9e-09 36.8 1.3 0.004 17.2 0.5 4.6 3 2 2 5 5 5 2 Dynamin family Roc PF08477.13 PSC70640.1 - 2.6e-08 34.1 0.4 0.078 13.2 0.0 3.9 4 0 0 4 4 4 2 Ras of Complex, Roc, domain of DAPkinase ABC_tran PF00005.27 PSC70640.1 - 7.6e-05 23.3 0.1 0.48 10.9 0.0 3.3 3 0 0 3 3 3 2 ABC transporter Ras PF00071.22 PSC70640.1 - 0.00011 21.8 0.2 0.13 11.8 0.0 3.3 4 0 0 4 4 4 1 Ras family SRPRB PF09439.10 PSC70640.1 - 0.0019 17.6 0.5 0.82 9.1 0.1 3.2 4 0 0 4 4 4 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 PSC70640.1 - 0.0062 16.8 0.2 4.4 7.6 0.0 4.0 3 2 0 3 3 2 1 AAA domain Complex1_LYR_2 PF13233.6 PSC70640.1 - 0.0067 17.2 0.1 0.017 15.8 0.1 1.7 1 0 0 1 1 1 1 Complex1_LYR-like TniB PF05621.11 PSC70640.1 - 0.01 15.3 0.0 5.5 6.3 0.0 2.6 3 0 0 3 3 3 0 Bacterial TniB protein MMR_HSR1_Xtn PF16897.5 PSC70640.1 - 0.035 14.1 0.0 3.4 7.7 0.0 3.1 3 0 0 3 3 3 0 C-terminal region of MMR_HSR1 domain ATPase_2 PF01637.18 PSC70640.1 - 0.052 13.5 0.0 12 5.7 0.0 2.7 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea NOG1 PF06858.14 PSC70640.1 - 0.073 12.9 0.0 0.31 10.8 0.0 2.2 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) AAA_24 PF13479.6 PSC70640.1 - 0.1 12.3 0.0 8.2 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 PSC70640.1 - 0.13 12.6 15.1 0.92 9.9 0.1 4.2 4 2 0 4 4 2 0 AAA ATPase domain cobW PF02492.19 PSC70640.1 - 0.18 11.4 1.2 4 7.0 0.1 3.2 3 1 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain HWE_HK PF07536.14 PSC70640.1 - 0.21 12.3 3.1 0.22 12.3 0.5 2.4 2 0 0 2 2 2 0 HWE histidine kinase GCP_C_terminal PF04130.13 PSC70641.1 - 1e-56 192.7 0.0 1.4e-56 192.2 0.0 1.1 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 PSC70641.1 - 2.5e-51 175.1 0.0 4.4e-51 174.3 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component N-terminal MCM PF00493.23 PSC70642.1 - 1.6e-71 240.0 0.0 3.2e-71 239.0 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain Inositol_P PF00459.25 PSC70642.1 - 2.7e-48 164.8 1.0 2.7e-48 164.8 1.0 1.8 2 0 0 2 2 2 1 Inositol monophosphatase family ABC_tran PF00005.27 PSC70642.1 - 1.2e-18 67.9 0.0 5.6e-17 62.5 0.0 2.4 2 0 0 2 2 2 1 ABC transporter MCM_OB PF17207.3 PSC70642.1 - 1.7e-17 63.4 0.1 3.7e-17 62.3 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PSC70642.1 - 1.5e-16 60.6 0.4 1.5e-16 60.6 0.4 2.6 2 0 0 2 2 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 PSC70642.1 - 1.3e-07 31.2 0.7 0.00057 19.3 0.0 3.5 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PSC70642.1 - 2.3e-07 30.9 0.1 0.00012 22.1 0.0 4.0 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 PSC70642.1 - 3e-05 23.7 0.1 0.0097 15.6 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_3 PF07726.11 PSC70642.1 - 8.6e-05 22.4 0.0 0.00024 21.0 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 PSC70642.1 - 0.00015 22.2 0.3 0.0052 17.2 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 PSC70642.1 - 0.00033 21.2 0.2 0.19 12.3 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.6 PSC70642.1 - 0.00069 19.5 0.0 0.37 10.5 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PSC70642.1 - 0.001 18.5 0.7 0.89 9.0 0.2 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain NACHT PF05729.12 PSC70642.1 - 0.0032 17.4 1.0 2 8.3 0.1 3.5 3 0 0 3 3 3 1 NACHT domain Sigma54_activat PF00158.26 PSC70642.1 - 0.017 14.8 1.3 0.14 11.8 0.1 2.7 2 1 0 2 2 2 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 PSC70642.1 - 0.031 14.3 0.1 3 7.9 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_7 PF12775.7 PSC70642.1 - 0.043 13.3 0.5 0.3 10.6 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_10 PF12846.7 PSC70642.1 - 0.053 12.4 0.0 4.9 6.0 0.0 2.4 2 0 0 2 2 2 0 AAA-like domain RsgA_GTPase PF03193.16 PSC70642.1 - 0.055 13.4 0.8 0.14 12.1 0.2 1.9 2 0 0 2 2 2 0 RsgA GTPase TsaE PF02367.17 PSC70642.1 - 0.058 13.4 0.2 14 5.7 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 PSC70642.1 - 0.088 13.1 1.1 15 5.8 0.0 3.2 2 1 0 2 2 2 0 AAA domain FBPase PF00316.20 PSC70642.1 - 0.1 12.1 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain AAA_33 PF13671.6 PSC70642.1 - 0.3 11.2 7.2 1.7 8.8 0.0 3.4 3 0 0 3 3 2 0 AAA domain AAA_13 PF13166.6 PSC70642.1 - 0.31 9.6 0.0 0.49 9.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain Sulfotransfer_2 PF03567.14 PSC70644.1 - 0.0082 16.1 0.3 0.024 14.5 0.3 1.7 1 1 0 1 1 1 1 Sulfotransferase family Solute_trans_a PF03619.16 PSC70645.1 - 1.6e-85 286.9 9.9 1.9e-85 286.6 9.9 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha fn3 PF00041.21 PSC70646.1 - 0.0014 19.0 3.7 0.02 15.2 0.1 3.6 5 0 0 5 5 5 1 Fibronectin type III domain Glyco_transf_92 PF01697.27 PSC70646.1 - 0.052 13.2 0.0 0.084 12.5 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 92 Glyco_transf_92 PF01697.27 PSC70647.1 - 0.0011 18.7 0.0 0.0017 18.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Atg8 PF02991.16 PSC70648.1 - 3.7e-48 162.0 0.1 5.9e-48 161.4 0.1 1.3 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like DUF563 PF04577.14 PSC70648.1 - 2.9e-10 40.6 0.0 6.9e-09 36.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF563) APG12 PF04110.13 PSC70648.1 - 0.00071 19.9 0.0 0.0012 19.2 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Keratin_2_head PF16208.5 PSC70649.1 - 0.022 14.9 4.5 0.029 14.5 4.5 1.3 1 0 0 1 1 1 0 Keratin type II head DivIC PF04977.15 PSC70649.1 - 0.037 13.8 0.2 0.064 13.0 0.2 1.4 1 0 0 1 1 1 0 Septum formation initiator GAS PF13851.6 PSC70649.1 - 0.04 13.3 0.3 0.07 12.5 0.3 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DivIVA PF05103.13 PSC70649.1 - 0.16 12.0 2.7 0.26 11.4 2.7 1.3 1 0 0 1 1 1 0 DivIVA protein DUF5427 PF10310.9 PSC70649.1 - 0.32 9.9 10.6 0.012 14.6 4.2 1.6 2 0 0 2 2 2 0 Family of unknown function (DUF5427) DUF677 PF05055.12 PSC70649.1 - 0.45 9.4 4.0 0.46 9.3 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF677) Macoilin PF09726.9 PSC70649.1 - 1.4 7.3 4.5 2 6.9 4.5 1.1 1 0 0 1 1 1 0 Macoilin family Ufm1 PF03671.14 PSC70651.1 - 3e-43 145.8 0.1 3.8e-43 145.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein Activator_LAG-3 PF11498.8 PSC70652.1 - 5.2 5.9 25.9 7.7 5.4 25.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 eIF-3_zeta PF05091.12 PSC70652.1 - 7.9 5.3 8.2 11 4.8 8.2 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DnaJ PF00226.31 PSC70653.1 - 1.2e-10 41.4 0.0 3.3e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 DnaJ domain U79_P34 PF03064.16 PSC70653.1 - 5.4 6.3 12.1 9 5.6 12.1 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 AAA PF00004.29 PSC70654.1 - 3.7e-16 59.8 0.0 8.6e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PSC70654.1 - 0.00045 20.6 0.0 0.00045 20.6 0.0 4.0 3 1 0 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 PSC70654.1 - 0.001 18.8 0.1 0.0023 17.7 0.1 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 PSC70654.1 - 0.0028 17.0 1.4 0.0034 16.8 0.1 1.7 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 PSC70654.1 - 0.0036 17.6 0.2 0.032 14.5 0.0 2.6 3 0 0 3 3 3 1 AAA domain IQ PF00612.27 PSC70654.1 - 0.0038 16.9 2.1 0.0038 16.9 2.1 2.2 2 0 0 2 2 2 1 IQ calmodulin-binding motif IstB_IS21 PF01695.17 PSC70654.1 - 0.0098 15.6 0.1 0.02 14.6 0.1 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_5 PF07728.14 PSC70654.1 - 0.011 15.8 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NACHT PF05729.12 PSC70654.1 - 0.05 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 PSC70654.1 - 0.069 13.3 0.0 0.069 13.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain Sigma54_activat PF00158.26 PSC70654.1 - 0.098 12.3 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain RNA_helicase PF00910.22 PSC70654.1 - 0.1 13.0 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase Sigma54_activ_2 PF14532.6 PSC70654.1 - 0.14 12.3 0.0 0.31 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 PSC70654.1 - 0.19 10.8 0.0 0.31 10.1 0.0 1.2 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 GRP PF07172.11 PSC70654.1 - 3.1 8.6 25.7 5.5 7.8 16.8 3.1 2 0 0 2 2 2 0 Glycine rich protein family SBP_bac_11 PF13531.6 PSC70655.1 - 3.4e-34 118.6 0.1 3.4e-34 118.6 0.1 2.1 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_1 PF01547.25 PSC70655.1 - 4.8e-08 33.3 0.9 1e-07 32.3 0.0 1.9 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein SBP_bac_8 PF13416.6 PSC70655.1 - 1.5e-05 25.0 0.0 5.1e-05 23.2 0.0 1.8 2 0 0 2 2 2 1 Bacterial extracellular solute-binding protein PBP_like PF12727.7 PSC70655.1 - 0.00038 19.6 0.0 0.00079 18.6 0.0 1.5 1 0 0 1 1 1 1 PBP superfamily domain WD40 PF00400.32 PSC70656.1 - 6.4e-07 30.0 3.0 0.024 15.5 0.0 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC70656.1 - 6.9e-07 29.5 0.0 8.3e-05 22.8 0.0 2.7 2 1 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain p450 PF00067.22 PSC70657.1 - 2.4e-79 267.2 0.0 1.8e-78 264.4 0.0 1.9 1 1 0 1 1 1 1 Cytochrome P450 Archease PF01951.16 PSC70661.1 - 1.1e-45 155.2 0.0 1.5e-45 154.8 0.0 1.2 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) PEMT PF04191.13 PSC70662.1 - 2e-10 41.0 0.2 7.8e-10 39.1 0.2 2.0 1 0 0 1 1 1 1 Phospholipid methyltransferase DUF1295 PF06966.12 PSC70662.1 - 2e-07 30.8 0.3 3.5e-07 30.0 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 PSC70662.1 - 0.00024 20.0 0.0 0.0015 17.4 0.0 1.9 2 0 0 2 2 2 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 PSC70662.1 - 0.046 14.1 0.2 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family CBFD_NFYB_HMF PF00808.23 PSC70663.1 - 8.9e-06 25.9 0.1 1.3e-05 25.4 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Mito_carr PF00153.27 PSC70664.1 - 8.2e-57 189.1 10.3 8.3e-20 70.5 0.5 3.4 2 1 1 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 PSC70664.1 - 0.01 16.0 0.0 3.6 7.9 0.0 3.3 3 1 0 3 3 3 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase DUF2723 PF11028.8 PSC70664.1 - 0.095 12.6 1.4 0.21 11.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2723) Presenilin PF01080.17 PSC70664.1 - 0.21 10.3 0.3 0.31 9.8 0.3 1.2 1 0 0 1 1 1 0 Presenilin HGTP_anticodon2 PF12745.7 PSC70664.1 - 0.22 11.0 3.8 0.3 10.5 3.8 1.2 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs MFMR_assoc PF16596.5 PSC70664.1 - 0.31 11.5 7.7 17 5.9 0.1 2.7 2 0 0 2 2 2 0 Disordered region downstream of MFMR FTZ PF03867.14 PSC70664.1 - 0.91 9.0 7.1 1.4 8.4 7.1 1.2 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region VHL PF01847.16 PSC70665.1 - 1.2e-08 34.7 0.0 2.1e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 VHL beta domain Pterin_bind PF00809.22 PSC70666.1 - 3.5e-85 285.6 0.0 5.3e-85 285.0 0.0 1.3 1 0 0 1 1 1 1 Pterin binding enzyme HPPK PF01288.20 PSC70666.1 - 5.4e-34 117.1 0.0 9.8e-34 116.2 0.0 1.4 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) Sacchrp_dh_NADP PF03435.18 PSC70666.1 - 0.016 15.5 0.3 0.14 12.4 0.0 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ACT_7 PF13840.6 PSC70666.1 - 0.11 12.3 0.1 1.3 8.8 0.0 2.3 2 0 0 2 2 2 0 ACT domain Mito_carr PF00153.27 PSC70667.1 - 1.9e-72 239.3 12.2 1.9e-25 88.6 0.3 3.4 4 0 0 4 4 4 3 Mitochondrial carrier protein Serine_protease PF18405.1 PSC70667.1 - 0.043 13.0 2.9 1.4 8.0 0.0 3.0 3 1 0 3 3 3 0 Gammaproteobacterial serine protease OprB PF04966.12 PSC70668.1 - 0.037 13.4 2.9 0.033 13.6 1.5 1.8 2 1 0 2 2 2 0 Carbohydrate-selective porin, OprB family Transferase PF02458.15 PSC70669.1 - 1e-07 31.0 0.0 3.2e-06 26.1 0.0 2.0 2 0 0 2 2 2 2 Transferase family GA-like PF17573.2 PSC70669.1 - 0.27 11.2 1.0 0.44 10.5 1.0 1.3 1 0 0 1 1 1 0 GA-like domain UBA PF00627.31 PSC70670.1 - 5.5e-07 29.4 0.0 0.00019 21.2 0.0 2.4 2 0 0 2 2 2 2 UBA/TS-N domain UBA_4 PF14555.6 PSC70670.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain HOIP-UBA PF16678.5 PSC70670.1 - 0.014 15.5 0.0 0.022 14.8 0.0 1.3 1 0 0 1 1 1 0 HOIP UBA domain pair DnaJ PF00226.31 PSC70671.1 - 1.5e-17 63.5 0.0 2.7e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain Cut8 PF08559.10 PSC70672.1 - 3.6e-26 92.2 0.0 4.3e-26 92.0 0.0 1.0 1 0 0 1 1 1 1 Cut8, nuclear proteasome tether protein Kinesin PF00225.23 PSC70673.1 - 1.2e-103 346.6 0.0 2.1e-103 345.8 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PSC70673.1 - 1.4e-22 80.2 0.0 4.2e-22 78.7 0.0 1.8 1 0 0 1 1 1 1 Microtubule binding Maf PF02545.14 PSC70673.1 - 0.018 14.9 0.1 0.061 13.2 0.1 1.9 1 0 0 1 1 1 0 Maf-like protein DUF1664 PF07889.12 PSC70673.1 - 0.68 10.0 15.2 0.16 12.0 2.8 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 PSC70673.1 - 1.1 9.4 11.7 0.44 10.7 1.3 2.7 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Acyltransferase PF01553.21 PSC70674.1 - 1.2e-08 34.6 0.0 2.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase TFIIA PF03153.13 PSC70675.1 - 0.085 12.8 11.2 0.14 12.1 11.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 PSC70675.1 - 0.26 9.9 0.9 0.28 9.8 0.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Spt20 PF12090.8 PSC70675.1 - 7.7 6.1 16.9 11 5.5 16.9 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 PSC70676.1 - 0.26 11.2 11.6 0.43 10.5 11.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDO_I PF05995.12 PSC70678.1 - 2.3e-18 66.1 0.0 9.1e-17 60.9 0.0 2.4 2 0 0 2 2 2 1 Cysteine dioxygenase type I bZIP_2 PF07716.15 PSC70678.1 - 0.0027 17.8 8.8 0.0027 17.8 8.8 2.0 2 0 0 2 2 2 1 Basic region leucine zipper Ribosomal_60s PF00428.19 PSC70678.1 - 0.024 15.2 0.8 0.024 15.2 0.8 5.2 4 1 0 4 4 4 0 60s Acidic ribosomal protein PCO_ADO PF07847.12 PSC70678.1 - 0.16 11.4 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 PCO_ADO bZIP_1 PF00170.21 PSC70678.1 - 0.19 11.8 10.8 0.031 14.4 6.8 1.7 2 0 0 2 2 2 0 bZIP transcription factor DUF4611 PF15387.6 PSC70678.1 - 0.34 11.1 0.0 0.34 11.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) CDO_I PF05995.12 PSC70679.1 - 2.3e-18 66.1 0.0 9e-17 60.9 0.0 2.4 2 0 0 2 2 2 1 Cysteine dioxygenase type I bZIP_2 PF07716.15 PSC70679.1 - 0.0086 16.1 11.4 0.0086 16.1 11.4 2.0 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 PSC70679.1 - 0.012 15.7 6.9 0.012 15.7 6.9 1.7 2 0 0 2 2 2 0 bZIP transcription factor Ribosomal_60s PF00428.19 PSC70679.1 - 0.024 15.2 0.8 0.024 15.2 0.8 5.2 4 1 0 4 4 4 0 60s Acidic ribosomal protein PCO_ADO PF07847.12 PSC70679.1 - 0.16 11.4 0.0 0.34 10.3 0.0 1.4 1 0 0 1 1 1 0 PCO_ADO DUF4611 PF15387.6 PSC70679.1 - 0.34 11.1 0.0 0.34 11.1 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) Mitoc_mL59 PF18126.1 PSC70680.1 - 4.1e-09 36.8 3.5 1.4e-07 31.9 3.5 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein mL59 Carb_kinase PF01256.17 PSC70682.1 - 6.4e-51 173.2 0.0 1.9e-50 171.7 0.0 1.8 1 1 0 1 1 1 1 Carbohydrate kinase Phos_pyr_kin PF08543.12 PSC70682.1 - 0.0024 17.3 0.2 0.017 14.5 0.0 2.2 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase CCDC106 PF15794.5 PSC70682.1 - 0.14 11.9 7.0 0.022 14.5 1.5 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Rootletin PF15035.6 PSC70682.1 - 0.14 12.1 9.7 19 5.2 12.9 2.5 2 1 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion TPR_MLP1_2 PF07926.12 PSC70682.1 - 0.2 11.7 23.7 0.087 12.9 10.0 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein HsbA PF12296.8 PSC70682.1 - 0.3 11.5 7.6 0.3 11.5 2.1 2.4 1 1 1 2 2 2 0 Hydrophobic surface binding protein A DUF2353 PF09789.9 PSC70682.1 - 0.31 10.3 4.8 0.18 11.2 2.8 1.5 1 1 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Fez1 PF06818.15 PSC70682.1 - 0.65 10.4 14.6 0.45 10.9 9.1 1.7 1 1 1 2 2 2 0 Fez1 PRKG1_interact PF15898.5 PSC70682.1 - 1.2 10.0 10.3 0.36 11.8 6.2 2.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain UPF0242 PF06785.11 PSC70682.1 - 1.3 9.1 3.0 2.8 8.0 2.8 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus BST2 PF16716.5 PSC70682.1 - 1.5 9.5 10.7 1 10.0 0.4 3.2 2 2 1 3 3 3 0 Bone marrow stromal antigen 2 Jnk-SapK_ap_N PF09744.9 PSC70682.1 - 1.7 8.8 13.6 1 9.6 2.9 2.6 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 TMF_TATA_bd PF12325.8 PSC70682.1 - 1.8 8.8 9.8 0.73 10.1 4.8 2.4 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding ZapB PF06005.12 PSC70682.1 - 2.8 8.5 17.2 8.6 6.9 0.3 3.5 2 1 1 3 3 3 0 Cell division protein ZapB RmuC PF02646.16 PSC70682.1 - 6.4 5.8 9.1 0.72 8.9 0.4 2.5 1 1 0 2 2 2 0 RmuC family Cep57_MT_bd PF06657.13 PSC70682.1 - 8.9 6.8 7.5 1.3 9.5 0.3 2.9 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Phage_GP20 PF06810.11 PSC70682.1 - 9.2 6.1 7.7 11 5.8 3.9 2.2 1 1 1 2 2 2 0 Phage minor structural protein GP20 Hat1_N PF10394.9 PSC70683.1 - 1.3e-26 93.8 0.0 1.8e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 PSC70683.1 - 2.3e-05 24.6 0.0 7.4e-05 23.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PSC70683.1 - 0.00074 19.9 0.0 0.0047 17.3 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PSC70683.1 - 0.12 12.3 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF4291 PF14124.6 PSC70684.1 - 1.1e-42 145.9 0.0 2.2e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Barwin PF00967.17 PSC70684.1 - 0.002 18.0 4.6 0.58 10.0 0.4 2.9 2 1 1 3 3 3 2 Barwin family DPBB_1 PF03330.18 PSC70684.1 - 0.053 13.8 0.0 3.2 8.1 0.0 2.7 3 0 0 3 3 3 0 Lytic transglycolase DUF4291 PF14124.6 PSC70685.1 - 1.1e-42 145.9 0.0 2.2e-42 145.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Barwin PF00967.17 PSC70685.1 - 0.002 18.0 4.6 0.58 10.0 0.4 2.9 2 1 1 3 3 3 2 Barwin family DPBB_1 PF03330.18 PSC70685.1 - 0.053 13.8 0.0 3.2 8.1 0.0 2.7 3 0 0 3 3 3 0 Lytic transglycolase Kin17_mid PF10357.9 PSC70686.1 - 3.6e-47 159.4 1.8 6.9e-47 158.5 1.8 1.5 1 0 0 1 1 1 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 PSC70686.1 - 2e-19 69.4 0.8 2e-19 69.4 0.8 2.2 3 0 0 3 3 3 1 KN17 SH3-like C-terminal domain zf-met PF12874.7 PSC70686.1 - 0.00042 20.6 5.4 0.00091 19.5 5.4 1.6 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PSC70686.1 - 0.00068 19.8 5.3 0.00068 19.8 5.3 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding KOW PF00467.29 PSC70686.1 - 0.036 14.0 5.9 0.093 12.7 0.0 4.0 3 2 1 4 4 4 0 KOW motif NdhS PF11623.8 PSC70686.1 - 0.14 11.8 0.1 0.31 10.7 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H dehydrogenase subunit S zf-C2H2_2 PF12756.7 PSC70686.1 - 0.5 10.7 9.3 0.092 13.1 3.7 2.4 1 1 0 2 2 2 0 C2H2 type zinc-finger (2 copies) XRN_N PF03159.18 PSC70687.1 - 2.8e-35 121.9 0.0 4e-35 121.4 0.0 1.2 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus SARAF PF06682.12 PSC70687.1 - 0.076 12.6 1.0 0.18 11.4 0.1 2.0 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Ribophorin_I PF04597.14 PSC70688.1 - 1.3e-106 357.5 0.0 1.7e-106 357.1 0.0 1.1 1 0 0 1 1 1 1 Ribophorin I ThiF PF00899.21 PSC70689.1 - 6.5e-60 202.5 0.3 9.2e-60 202.0 0.3 1.1 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 PSC70689.1 - 2.1e-12 47.5 0.0 7.9e-11 42.4 0.0 3.0 2 1 0 2 2 2 1 Rhodanese-like domain Sacchrp_dh_NADP PF03435.18 PSC70689.1 - 0.0009 19.5 0.5 0.0031 17.8 0.5 1.8 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain FAD_binding_3 PF01494.19 PSC70689.1 - 0.0019 17.5 0.1 0.0052 16.1 0.1 1.6 2 0 0 2 2 2 1 FAD binding domain DUF3138 PF11336.8 PSC70689.1 - 0.0098 14.6 0.1 0.017 13.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3138) ApbA PF02558.16 PSC70689.1 - 0.027 14.1 0.2 0.045 13.4 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 PSC70689.1 - 0.067 12.8 0.0 0.099 12.2 0.0 1.2 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 PSC70689.1 - 0.069 13.0 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 PSC70689.1 - 0.15 12.1 0.1 0.32 11.0 0.1 1.6 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase F-box-like PF12937.7 PSC70690.1 - 5.4e-07 29.4 0.9 4.3e-06 26.5 0.3 2.7 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PSC70690.1 - 0.00021 21.0 1.7 0.0019 18.0 0.1 3.1 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.33 PSC70690.1 - 2.1 9.2 6.9 2.8 8.8 0.8 3.9 3 1 0 3 3 3 0 Leucine Rich Repeat DUF3419 PF11899.8 PSC70691.1 - 1.3e-103 347.2 0.0 2.1e-103 346.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3419) MutS_V PF00488.21 PSC70691.1 - 4.7e-66 222.4 0.0 7e-66 221.8 0.0 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 PSC70691.1 - 4.9e-30 105.2 0.0 9.2e-30 104.3 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 PSC70691.1 - 1.1e-26 93.3 0.0 2e-26 92.4 0.0 1.5 1 0 0 1 1 1 1 MutS domain I Methyltransf_23 PF13489.6 PSC70691.1 - 1.5e-09 37.9 0.0 1.4e-08 34.8 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC70691.1 - 2.1e-09 37.9 0.1 1.8e-07 31.8 0.0 3.5 4 0 0 4 4 2 1 Methyltransferase domain MutS_IV PF05190.18 PSC70691.1 - 8.2e-06 26.1 0.0 1.5e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 MutS family domain IV MutS_II PF05188.17 PSC70691.1 - 8.9e-06 26.0 0.0 2.9e-05 24.3 0.0 1.9 1 1 0 1 1 1 1 MutS domain II Methyltransf_11 PF08241.12 PSC70691.1 - 2.4e-05 24.9 0.0 0.00017 22.2 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC70691.1 - 2.7e-05 23.6 0.0 5.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 PSC70691.1 - 2.8e-05 24.0 0.0 0.00025 20.8 0.0 2.4 3 0 0 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 PSC70691.1 - 4.6e-05 24.1 0.0 0.00041 21.0 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC70691.1 - 0.00068 19.5 0.0 0.0018 18.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 PSC70691.1 - 0.16 11.5 0.0 0.32 10.5 0.0 1.4 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase P19Arf_N PF07392.12 PSC70691.1 - 4.8 7.7 5.8 5 7.6 1.9 3.1 2 0 0 2 2 2 0 Cyclin-dependent kinase inhibitor 2a p19Arf N-terminus AAA_16 PF13191.6 PSC70691.1 - 5.6 7.3 5.7 21 5.5 0.0 3.6 4 0 0 4 4 3 0 AAA ATPase domain Trypsin PF00089.26 PSC70692.1 - 6.1e-31 108.0 0.0 1.1e-30 107.2 0.0 1.4 1 1 0 1 1 1 1 Trypsin IPTL-CTERM PF18203.1 PSC70692.1 - 2.8 7.9 6.5 1.6 8.7 3.6 2.2 2 0 0 2 2 2 0 IPTL-CTERM motif Internalin_N PF12354.8 PSC70693.1 - 0.051 13.7 0.3 0.1 12.7 0.3 1.5 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal Rtf2 PF04641.12 PSC70694.1 - 6.8e-45 153.5 0.0 9.3e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 PSC70694.1 - 0.11 12.4 0.5 0.77 9.7 0.0 2.3 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-CCCH_6 PF18585.1 PSC70694.1 - 0.17 11.8 0.2 0.9 9.5 0.0 2.1 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 IHABP4_N PF16174.5 PSC70694.1 - 2.7 8.6 13.5 4.4 7.9 13.5 1.3 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal DUF218 PF02698.17 PSC70695.1 - 0.0071 16.4 0.0 0.016 15.2 0.0 1.6 2 0 0 2 2 2 1 DUF218 domain PFK PF00365.20 PSC70696.1 - 4.3e-63 213.3 0.2 5.8e-63 212.9 0.2 1.1 1 0 0 1 1 1 1 Phosphofructokinase Pkinase PF00069.25 PSC70697.1 - 2.8e-63 213.7 0.0 3.9e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC70697.1 - 2.8e-47 161.2 0.0 4.3e-47 160.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase YccF PF03733.13 PSC70697.1 - 5.3e-17 62.3 21.9 1.9e-13 50.9 3.6 2.4 2 0 0 2 2 2 2 Inner membrane component domain Pkinase_fungal PF17667.1 PSC70697.1 - 4.5e-08 32.3 0.0 8.1e-08 31.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PSC70697.1 - 0.00027 20.4 0.2 0.0044 16.4 0.0 2.2 2 0 0 2 2 2 1 Kinase-like SOGA PF11365.8 PSC70697.1 - 0.0065 17.6 0.6 0.023 15.8 0.6 1.9 1 0 0 1 1 1 1 Protein SOGA Leu_zip PF15294.6 PSC70697.1 - 0.011 15.3 0.7 0.021 14.4 0.7 1.4 1 0 0 1 1 1 0 Leucine zipper HAP1_N PF04849.13 PSC70697.1 - 0.017 14.3 1.3 0.03 13.5 1.3 1.3 1 0 0 1 1 1 0 HAP1 N-terminal conserved region Kdo PF06293.14 PSC70697.1 - 0.021 14.2 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PSC70697.1 - 0.028 14.0 0.0 0.073 12.7 0.0 1.7 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 CASP_C PF08172.12 PSC70697.1 - 0.048 13.0 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 CASP C terminal APH PF01636.23 PSC70697.1 - 0.06 13.3 0.0 0.06 13.3 0.0 4.1 4 1 1 5 5 5 0 Phosphotransferase enzyme family GAS PF13851.6 PSC70697.1 - 0.092 12.1 3.1 0.18 11.1 3.1 1.4 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Nnf1 PF03980.14 PSC70697.1 - 0.11 12.9 2.1 1.8 9.0 1.0 3.1 3 0 0 3 3 3 0 Nnf1 NUDE_C PF04880.13 PSC70697.1 - 0.16 12.4 2.7 0.39 11.2 0.1 2.4 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region Trypsin PF00089.26 PSC70699.1 - 4.9e-18 65.7 0.0 5.9e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PSC70699.1 - 0.16 12.8 0.0 0.25 12.2 0.0 1.2 1 0 0 1 1 1 0 Trypsin-like peptidase domain GFO_IDH_MocA PF01408.22 PSC70700.1 - 1.6e-23 83.8 0.1 2.6e-23 83.1 0.1 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold NAD_binding_3 PF03447.16 PSC70700.1 - 1.3e-05 25.8 0.0 2.8e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 PSC70700.1 - 0.094 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Peptidase_M43 PF05572.13 PSC70701.1 - 9.7e-15 54.8 0.0 1.7e-14 54.0 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A Reprolysin_5 PF13688.6 PSC70701.1 - 0.00018 21.7 0.6 0.00027 21.1 0.6 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 PSC70701.1 - 0.0023 18.4 0.0 0.0038 17.7 0.0 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 PSC70701.1 - 0.0037 16.9 0.4 0.0072 16.0 0.4 1.5 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 PSC70701.1 - 0.18 11.7 0.1 0.29 11.0 0.1 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M57 PF12388.8 PSC70701.1 - 1.1 8.8 2.9 1.4 8.5 1.8 1.7 1 1 1 2 2 2 0 Dual-action HEIGH metallo-peptidase PHD PF00628.29 PSC70702.1 - 3.2e-10 39.7 13.0 5.5e-10 39.0 13.0 1.4 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 PSC70702.1 - 0.52 10.2 4.7 1.1 9.2 4.7 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PHD_2 PF13831.6 PSC70702.1 - 1.6 8.3 7.2 3 7.5 7.2 1.4 1 0 0 1 1 1 0 PHD-finger Branch PF02485.21 PSC70704.1 - 2e-37 129.0 0.0 2e-37 129.0 0.0 2.1 3 0 0 3 3 2 1 Core-2/I-Branching enzyme Ribosomal_60s PF00428.19 PSC70704.1 - 0.018 15.6 16.4 0.018 15.6 16.4 6.1 3 2 2 5 5 2 0 60s Acidic ribosomal protein Draxin PF15550.6 PSC70704.1 - 0.19 11.5 15.3 0.35 10.7 15.3 1.3 1 0 0 1 1 1 0 Draxin Zip PF02535.22 PSC70704.1 - 0.23 10.7 4.8 0.37 9.9 4.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Apt1 PF10351.9 PSC70704.1 - 0.25 10.1 12.2 0.44 9.4 12.2 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain LRIF1 PF15741.5 PSC70704.1 - 0.39 9.2 14.4 0.55 8.7 14.4 1.1 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 DUF572 PF04502.13 PSC70704.1 - 0.43 10.2 21.9 0.22 11.1 17.6 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) FAM76 PF16046.5 PSC70704.1 - 1 8.6 18.1 1.7 7.9 18.1 1.2 1 0 0 1 1 1 0 FAM76 protein Macoilin PF09726.9 PSC70704.1 - 2 6.8 15.0 3.4 6.1 15.0 1.2 1 0 0 1 1 1 0 Macoilin family CAML PF14963.6 PSC70704.1 - 2.1 8.4 7.3 39 4.2 8.2 2.1 2 0 0 2 2 2 0 Calcium signal-modulating cyclophilin ligand Rrn6 PF10214.9 PSC70704.1 - 2.3 6.6 13.4 3.3 6.1 13.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DDHD PF02862.17 PSC70704.1 - 4.6 7.3 8.6 1 9.5 5.0 1.7 2 0 0 2 2 2 0 DDHD domain DUF755 PF05501.11 PSC70704.1 - 4.6 7.5 46.2 8.5 6.7 46.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF4551 PF15087.6 PSC70704.1 - 5.6 5.7 8.8 8.8 5.0 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Presenilin PF01080.17 PSC70704.1 - 6.1 5.5 12.7 13 4.4 12.7 1.5 1 0 0 1 1 1 0 Presenilin HemY_N PF07219.13 PSC70704.1 - 7.2 6.9 24.5 0.28 11.4 3.8 3.1 3 0 0 3 3 2 0 HemY protein N-terminus CPSF100_C PF13299.6 PSC70704.1 - 9.1 6.4 14.5 64 3.7 0.0 2.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Pkinase PF00069.25 PSC70705.1 - 6.9e-55 186.2 0.0 1e-54 185.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC70705.1 - 1e-32 113.4 0.0 1.5e-32 112.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC70705.1 - 3.9e-05 23.1 0.0 8.9e-05 21.9 0.0 1.5 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PSC70705.1 - 0.00061 18.7 0.1 0.0015 17.4 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 PSC70705.1 - 0.034 14.1 0.1 0.034 14.1 0.1 3.0 3 1 1 4 4 4 0 Phosphotransferase enzyme family Urm1 PF09138.11 PSC70706.1 - 6.5e-31 106.6 0.0 7.2e-31 106.4 0.0 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 PSC70706.1 - 2.2e-05 25.0 0.0 3.8e-05 24.2 0.0 1.4 1 1 0 1 1 1 1 ThiS family HNH_5 PF14279.6 PSC70708.1 - 8.4e-16 57.6 0.5 1.8e-15 56.5 0.5 1.6 2 0 0 2 2 2 1 HNH endonuclease HNH PF01844.23 PSC70708.1 - 1.7e-13 50.5 0.6 2.6e-13 49.9 0.6 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH_4 PF13395.6 PSC70708.1 - 1.4e-08 34.5 0.0 3.5e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 HNH endonuclease Glycos_transf_1 PF00534.20 PSC70709.1 - 1.4e-14 54.0 0.0 9.5e-14 51.3 0.0 2.0 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PSC70709.1 - 3.3e-12 47.0 0.0 6.6e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 PSC70709.1 - 1.2e-07 32.0 0.2 4.3e-07 30.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 PSC70709.1 - 0.0015 18.6 0.0 0.0045 17.0 0.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 PSC70709.1 - 0.0036 17.8 0.8 0.0036 17.8 0.8 3.3 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glycogen_syn PF05693.13 PSC70709.1 - 0.12 10.9 0.0 0.15 10.5 0.0 1.2 1 0 0 1 1 1 0 Glycogen synthase HSP70 PF00012.20 PSC70710.1 - 2.4e-261 868.2 12.2 3e-261 867.9 12.2 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PSC70710.1 - 1.1e-15 57.3 5.7 9.9e-15 54.2 0.1 2.7 3 0 0 3 3 3 2 MreB/Mbl protein FtsA PF14450.6 PSC70710.1 - 3.4e-06 27.4 0.8 0.0014 19.0 0.0 3.8 3 1 0 3 3 3 1 Cell division protein FtsA LysM PF01476.20 PSC70710.1 - 1.9e-05 24.6 0.0 5.5e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 LysM domain VSG_B PF13206.6 PSC70710.1 - 0.043 13.1 2.8 0.091 12.0 2.8 1.5 1 0 0 1 1 1 0 Trypanosomal VSG domain DUF4588 PF15251.6 PSC70710.1 - 0.073 12.8 2.3 0.3 10.8 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4588) StbA PF06406.11 PSC70710.1 - 0.095 11.9 1.8 0.25 10.5 0.0 2.5 3 0 0 3 3 3 0 StbA protein Com_YlbF PF06133.11 PSC70710.1 - 0.75 10.4 7.6 2 9.1 7.6 1.6 1 0 0 1 1 1 0 Control of competence regulator ComK, YlbF/YmcA DUF1090 PF06476.12 PSC70710.1 - 3 8.0 9.9 7.1 6.8 9.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) Hemerythrin PF01814.23 PSC70711.1 - 0.62 10.7 10.2 8 7.1 0.1 4.2 4 0 0 4 4 4 0 Hemerythrin HHE cation binding domain Chloroa_b-bind PF00504.21 PSC70712.1 - 1.5e-11 45.1 3.3 9.5e-06 26.2 0.4 2.2 1 1 1 2 2 2 2 Chlorophyll A-B binding protein Ras PF00071.22 PSC70713.1 - 8.7e-61 204.3 0.1 1e-60 204.0 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PSC70713.1 - 4.6e-35 120.4 0.0 6.7e-35 119.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PSC70713.1 - 1.5e-16 60.3 0.0 2e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PSC70713.1 - 3.8e-06 27.0 0.0 6.6e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PSC70713.1 - 0.00016 21.6 0.1 0.36 10.7 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 PSC70713.1 - 0.00036 20.0 0.0 0.00047 19.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 PSC70713.1 - 0.0096 15.5 0.1 0.53 9.8 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 PSC70713.1 - 0.016 15.6 0.1 0.036 14.5 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain GTP_EFTU PF00009.27 PSC70713.1 - 0.017 14.7 0.0 0.045 13.3 0.0 1.6 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 PSC70713.1 - 0.03 14.0 0.0 0.062 13.0 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PSC70713.1 - 0.049 13.6 0.1 0.7 9.9 0.0 2.3 2 1 0 2 2 2 0 AAA domain (dynein-related subfamily) TniB PF05621.11 PSC70713.1 - 0.065 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_22 PF13401.6 PSC70713.1 - 0.1 12.9 0.1 0.21 11.8 0.0 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 PSC70713.1 - 0.16 11.6 0.3 11 5.6 0.0 2.3 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain CitMHS PF03600.16 PSC70714.1 - 6e-63 212.8 0.0 6e-63 212.8 0.0 2.6 2 1 0 2 2 2 1 Citrate transporter Ank_2 PF12796.7 PSC70714.1 - 1.1e-42 144.5 1.7 6.9e-09 36.2 0.0 5.6 1 1 4 5 5 5 5 Ankyrin repeats (3 copies) TrkA_C PF02080.21 PSC70714.1 - 2.5e-41 139.3 1.2 5.8e-11 42.1 0.1 4.4 4 0 0 4 4 4 4 TrkA-C domain Ank_4 PF13637.6 PSC70714.1 - 2.4e-22 79.0 7.8 1.2e-05 25.7 0.1 6.5 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC70714.1 - 2.2e-19 69.2 14.7 0.00014 22.1 0.0 8.5 3 1 5 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC70714.1 - 3.5e-18 63.8 10.5 0.00068 19.9 0.0 10.4 10 0 0 10 10 10 3 Ankyrin repeat Ank PF00023.30 PSC70714.1 - 2.4e-12 46.7 27.7 4.8e-05 23.6 0.2 9.5 10 0 0 10 10 10 3 Ankyrin repeat GAF_2 PF13185.6 PSC70714.1 - 7.4e-09 36.0 0.6 4.2e-08 33.6 0.6 2.4 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 PSC70714.1 - 5.9e-05 23.7 0.2 5.9e-05 23.7 0.2 2.3 2 0 0 2 2 2 1 GAF domain LppA PF16708.5 PSC70714.1 - 0.0015 18.4 2.0 0.0021 18.0 0.3 2.1 2 0 0 2 2 2 1 Lipoprotein confined to pathogenic Mycobacterium RNA_pol_Rbc25 PF08292.12 PSC70715.1 - 1.9e-28 99.3 0.0 2.6e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 PSC70715.1 - 8.7e-16 58.1 0.1 2.1e-15 56.8 0.1 1.6 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.23 PSC70715.1 - 0.0036 17.6 0.0 0.0063 16.8 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain Lipase_GDSL_2 PF13472.6 PSC70716.1 - 8.5e-13 49.1 0.0 1e-12 48.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 PSC70716.1 - 0.0033 17.4 0.0 0.0052 16.8 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase tRNA-synt_2 PF00152.20 PSC70717.1 - 7.9e-74 248.5 0.0 7.9e-56 189.4 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 PSC70717.1 - 4.1e-17 61.9 0.1 8.3e-17 60.9 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 PSC70717.1 - 1.5e-06 27.9 0.2 0.0073 15.8 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) Ntox1 PF15500.6 PSC70717.1 - 0.042 14.2 2.1 8.2 6.8 0.4 2.6 2 0 0 2 2 2 0 Putative RNase-like toxin, toxin_1 tRNA_anti_2 PF13742.6 PSC70717.1 - 0.086 13.1 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Radical_SAM PF04055.21 PSC70718.1 - 1.2e-18 68.0 0.0 2e-18 67.3 0.0 1.3 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 PSC70718.1 - 6e-18 65.4 0.0 8.8e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 PSC70718.1 - 5.1e-10 39.5 0.0 1.1e-09 38.4 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain PIG-S PF10510.9 PSC70720.1 - 0.0007 18.6 1.6 0.0032 16.4 0.2 2.3 3 0 0 3 3 3 1 Phosphatidylinositol-glycan biosynthesis class S protein DUF3123 PF11321.8 PSC70720.1 - 0.25 12.0 5.4 0.84 10.3 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) GAF_2 PF13185.6 PSC70723.1 - 0.0075 16.6 0.2 0.02 15.2 0.2 1.8 1 0 0 1 1 1 1 GAF domain 4HBT PF03061.22 PSC70724.1 - 7e-32 109.6 4.9 1.3e-15 57.5 0.2 2.5 2 0 0 2 2 2 2 Thioesterase superfamily Peripla_BP_2 PF01497.18 PSC70725.1 - 8.7e-05 22.2 0.0 0.00036 20.2 0.0 1.8 1 1 0 1 1 1 1 Periplasmic binding protein PRA1 PF03208.19 PSC70728.1 - 3.8e-39 133.6 0.2 4.8e-39 133.3 0.2 1.1 1 0 0 1 1 1 1 PRA1 family protein BatA PF07584.11 PSC70728.1 - 0.036 14.4 0.7 0.11 12.9 0.7 1.8 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal Trp_oprn_chp PF09534.10 PSC70728.1 - 0.087 12.6 5.2 0.15 11.9 5.2 1.5 1 1 0 1 1 1 0 Tryptophan-associated transmembrane protein (Trp_oprn_chp) DUF3341 PF11821.8 PSC70728.1 - 0.52 9.9 3.2 1.1 8.8 3.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3341) CTD_bind PF04818.13 PSC70729.1 - 0.035 14.9 0.0 0.12 13.2 0.0 1.9 2 0 0 2 2 2 0 RNA polymerase II-binding domain. TFIIA PF03153.13 PSC70729.1 - 1.7 8.6 13.1 2.5 8.0 13.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GCFC PF07842.12 PSC70730.1 - 1.9e-10 40.9 0.0 2.3e-09 37.3 0.0 2.2 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein Pex19 PF04614.12 PSC70730.1 - 0.013 15.3 0.2 0.036 13.8 0.2 1.8 1 0 0 1 1 1 0 Pex19 protein family AzlC PF03591.14 PSC70730.1 - 1.3 9.4 4.7 2.5 8.5 4.7 1.4 1 0 0 1 1 1 0 AzlC protein Helicase_C_4 PF13871.6 PSC70731.1 - 4e-196 649.8 0.1 1.1e-100 336.8 0.0 2.4 2 0 0 2 2 2 2 C-terminal domain on Strawberry notch homologue AAA_34 PF13872.6 PSC70731.1 - 2.4e-168 558.6 0.0 6.3e-106 353.7 0.0 3.0 2 1 0 2 2 2 2 P-loop containing NTP hydrolase pore-1 Helicase_C PF00271.31 PSC70731.1 - 5.1e-05 23.6 0.4 0.58 10.5 0.1 2.8 2 0 0 2 2 2 2 Helicase conserved C-terminal domain PHD PF00628.29 PSC70731.1 - 8.9e-05 22.3 11.2 0.0002 21.2 11.2 1.6 1 0 0 1 1 1 1 PHD-finger Mo-co_dimer PF03404.16 PSC70731.1 - 0.0001 22.3 0.4 0.45 10.5 0.1 2.6 2 0 0 2 2 2 2 Mo-co oxidoreductase dimerisation domain PHD_2 PF13831.6 PSC70731.1 - 0.019 14.5 3.1 0.037 13.6 3.1 1.5 1 0 0 1 1 1 0 PHD-finger Zf_RING PF16744.5 PSC70731.1 - 0.46 10.6 6.5 1.2 9.4 6.5 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger Methyltransf_25 PF13649.6 PSC70732.1 - 9.2e-16 58.3 0.0 3e-15 56.7 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC70732.1 - 8.6e-14 52.0 0.0 1.8e-13 50.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC70732.1 - 5.9e-11 42.5 0.0 1.2e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Usp PF00582.26 PSC70732.1 - 5.8e-10 39.8 0.0 4.9e-08 33.6 0.0 3.0 2 1 0 2 2 2 1 Universal stress protein family Methyltransf_12 PF08242.12 PSC70732.1 - 9.9e-09 35.9 0.0 2.4e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC70732.1 - 5.8e-08 32.4 0.0 1.4e-07 31.1 0.0 1.5 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 PSC70732.1 - 7e-06 25.9 0.0 3.9e-05 23.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 PSC70732.1 - 0.0016 18.2 0.0 0.0032 17.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) MTS PF05175.14 PSC70732.1 - 0.051 13.1 0.0 0.12 11.9 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain PKcGMP_CC PF16808.5 PSC70732.1 - 0.052 13.4 1.0 0.098 12.5 1.0 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Ig_3 PF13927.6 PSC70732.1 - 0.13 12.9 0.0 3.6 8.3 0.0 2.5 2 0 0 2 2 2 0 Immunoglobulin domain peroxidase PF00141.23 PSC70734.1 - 1.5e-37 129.5 0.1 1.7e-36 126.0 0.1 1.9 1 1 0 1 1 1 1 Peroxidase Peptidase_S41 PF03572.18 PSC70735.1 - 5.4e-46 156.2 0.0 8.4e-46 155.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 PSC70735.1 - 3.8e-09 36.3 0.4 3.8e-09 36.3 0.4 2.5 3 0 0 3 3 3 1 PDZ domain PDZ PF00595.24 PSC70735.1 - 9e-05 22.7 0.0 0.00025 21.4 0.0 1.7 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PSC70735.1 - 0.0031 17.8 0.0 0.013 15.8 0.0 2.0 1 1 0 1 1 1 1 PDZ domain Lipase_3 PF01764.25 PSC70736.1 - 7.4e-24 84.2 0.0 5.1e-22 78.3 0.0 2.4 1 1 0 1 1 1 1 Lipase (class 3) C2 PF00168.30 PSC70736.1 - 3.3e-17 62.6 0.0 5.2e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 C2 domain Chorion_3 PF05387.11 PSC70736.1 - 0.64 9.6 10.0 2.2 7.8 10.0 1.9 1 0 0 1 1 1 0 Chorion family 3 Peptidase_S24 PF00717.23 PSC70737.1 - 2.7e-11 43.2 0.0 4.5e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like NTP_transferase PF00483.23 PSC70738.1 - 3.4e-74 249.6 0.0 4.4e-74 249.2 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 PSC70738.1 - 0.00062 20.2 0.0 0.0014 19.0 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain RRM_1 PF00076.22 PSC70739.1 - 9.8e-26 89.4 0.0 3.5e-12 46.0 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PSC70739.1 - 1.2e-07 31.4 0.0 0.0098 15.5 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PSC70739.1 - 0.0016 18.2 0.0 0.7 9.8 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 PSC70739.1 - 0.068 13.2 0.0 21 5.2 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.11 PSC70739.1 - 0.099 12.5 0.0 0.2 11.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) DUF4523 PF15023.6 PSC70739.1 - 0.14 12.0 0.0 0.37 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) RRM_1 PF00076.22 PSC70740.1 - 1e-25 89.3 0.0 3.5e-12 46.0 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PSC70740.1 - 1.2e-07 31.4 0.0 0.0099 15.5 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PSC70740.1 - 0.0016 18.2 0.0 0.71 9.8 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 PSC70740.1 - 0.069 13.2 0.0 21 5.2 0.0 2.9 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif DUF1866 PF08952.11 PSC70740.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1866) DUF4523 PF15023.6 PSC70740.1 - 0.14 12.0 0.0 0.37 10.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) UCH PF00443.29 PSC70741.1 - 2.4e-36 125.5 0.0 8.1e-36 123.8 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PSC70741.1 - 2.5e-07 30.6 0.0 3.5e-06 26.8 0.0 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 PSC70741.1 - 0.18 11.2 0.2 1.4 8.3 0.0 2.2 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase EamA PF00892.20 PSC70742.1 - 0.021 15.0 2.2 0.021 15.0 2.2 2.7 3 0 0 3 3 3 0 EamA-like transporter family Rab5ip PF07019.12 PSC70742.1 - 0.059 14.0 3.1 0.26 11.9 3.1 2.2 1 1 0 1 1 1 0 Rab5-interacting protein (Rab5ip) DUF2070 PF09843.9 PSC70742.1 - 0.18 10.0 3.0 0.33 9.2 3.0 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) SUIM_assoc PF16619.5 PSC70742.1 - 1.9 8.6 9.9 3.3 7.9 9.9 1.3 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CBM_20 PF00686.19 PSC70743.1 - 3.3e-18 65.4 0.0 1e-17 63.8 0.0 1.8 1 0 0 1 1 1 1 Starch binding domain Fer2 PF00111.27 PSC70743.1 - 2.1e-11 43.6 2.5 4.3e-11 42.6 0.9 2.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain ERM PF00769.19 PSC70743.1 - 0.00027 20.9 8.0 0.00027 20.9 8.0 7.2 4 2 1 5 5 5 2 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 PSC70743.1 - 0.3 11.1 68.4 0.14 12.2 3.0 7.9 5 2 1 7 7 7 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 FlaC_arch PF05377.11 PSC70743.1 - 0.4 11.1 12.7 0.25 11.7 0.2 5.0 5 1 0 5 5 5 0 Flagella accessory protein C (FlaC) DUF3818 PF12825.7 PSC70743.1 - 4.7 6.1 6.6 13 4.6 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function in PX-proteins (DUF3818) AAA PF00004.29 PSC70744.1 - 3e-54 183.0 0.0 1.9e-44 151.3 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PSC70744.1 - 2.5e-08 34.5 17.3 0.00033 21.1 0.2 5.0 4 1 1 5 5 5 2 AAA ATPase domain RuvB_N PF05496.12 PSC70744.1 - 1.4e-06 28.2 0.0 0.0009 19.0 0.0 2.8 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 PSC70744.1 - 1.4e-06 28.5 0.0 0.019 15.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 PSC70744.1 - 2.3e-06 27.6 0.1 0.02 14.9 0.1 3.0 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 PSC70744.1 - 1.2e-05 25.1 2.5 1.2e-05 25.1 2.5 3.2 2 1 0 2 2 2 1 AAA+ lid domain AAA_25 PF13481.6 PSC70744.1 - 4.3e-05 23.2 0.6 0.0051 16.4 0.0 3.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 PSC70744.1 - 9.4e-05 22.2 0.1 0.013 15.2 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_22 PF13401.6 PSC70744.1 - 0.00012 22.4 0.2 0.032 14.5 0.1 3.3 2 1 1 3 3 3 1 AAA domain ATPase PF06745.13 PSC70744.1 - 0.00028 20.3 0.0 0.0011 18.4 0.0 1.7 2 0 0 2 2 2 1 KaiC AAA_18 PF13238.6 PSC70744.1 - 0.00034 21.2 0.0 0.17 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 PSC70744.1 - 0.00037 19.8 0.2 0.031 13.5 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain Mg_chelatase PF01078.21 PSC70744.1 - 0.0004 19.8 0.2 0.053 12.9 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 PSC70744.1 - 0.00099 19.5 0.0 2.1 8.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 PSC70744.1 - 0.001 19.1 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 PSC70744.1 - 0.0032 17.8 0.0 0.092 13.1 0.0 2.2 2 0 0 2 2 2 1 RNA helicase AAA_11 PF13086.6 PSC70744.1 - 0.0041 16.9 0.2 1.9 8.2 0.0 2.6 3 0 0 3 3 3 1 AAA domain PhoH PF02562.16 PSC70744.1 - 0.012 15.1 3.2 0.23 10.9 0.0 3.0 3 0 0 3 3 3 0 PhoH-like protein Sigma54_activat PF00158.26 PSC70744.1 - 0.015 15.0 0.0 1.1 9.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.13 PSC70744.1 - 0.018 14.2 0.0 0.18 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Vps4_C PF09336.10 PSC70744.1 - 0.02 14.9 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_7 PF12775.7 PSC70744.1 - 0.025 14.1 0.0 0.22 11.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_29 PF13555.6 PSC70744.1 - 0.029 14.1 0.6 4.4 7.1 0.0 2.8 3 0 0 3 3 2 0 P-loop containing region of AAA domain NACHT PF05729.12 PSC70744.1 - 0.029 14.3 0.2 1.6 8.6 0.0 2.9 3 0 0 3 3 3 0 NACHT domain AAA_24 PF13479.6 PSC70744.1 - 0.031 14.0 0.0 0.37 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain Parvo_NS1 PF01057.17 PSC70744.1 - 0.068 12.3 0.0 0.15 11.2 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 NTPase_1 PF03266.15 PSC70744.1 - 0.071 13.0 0.0 5.3 6.9 0.0 2.3 2 0 0 2 2 2 0 NTPase Sigma54_activ_2 PF14532.6 PSC70744.1 - 0.074 13.2 0.0 3.2 7.9 0.0 2.9 2 1 1 3 3 3 0 Sigma-54 interaction domain AAA_19 PF13245.6 PSC70744.1 - 0.076 13.3 0.1 5.9 7.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PSC70744.1 - 0.084 13.1 3.2 0.6 10.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_2 PF07724.14 PSC70744.1 - 0.13 12.3 0.0 0.44 10.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_3 PF07726.11 PSC70744.1 - 0.14 12.0 0.0 1.1 9.1 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 PSC70744.1 - 0.24 11.3 0.0 27 4.6 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain DUF2075 PF09848.9 PSC70744.1 - 0.28 10.4 0.3 0.81 8.9 0.0 1.9 3 0 0 3 3 2 0 Uncharacterized conserved protein (DUF2075) AIG1 PF04548.16 PSC70745.1 - 2.3e-22 79.4 0.0 4.8e-22 78.3 0.0 1.6 1 0 0 1 1 1 1 AIG1 family Ank_4 PF13637.6 PSC70745.1 - 9.9e-18 64.3 0.2 1.7e-11 44.4 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC70745.1 - 1e-14 54.4 3.9 1.8e-08 34.5 0.1 4.3 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PSC70745.1 - 2.1e-13 50.7 0.2 6e-13 49.2 0.2 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 PSC70745.1 - 5.1e-13 48.8 0.4 4.2e-05 23.8 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 PSC70745.1 - 3.7e-11 42.2 0.1 0.00078 19.7 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat STI1 PF17830.1 PSC70745.1 - 2.5e-07 30.5 13.7 9.7e-06 25.4 0.1 3.3 1 1 1 2 2 2 2 STI1 domain MMR_HSR1 PF01926.23 PSC70745.1 - 7.1e-07 29.3 0.0 1.4e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 PSC70745.1 - 3.5e-05 24.3 0.7 0.0001 22.7 0.1 2.2 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 PSC70745.1 - 0.00062 19.7 0.0 0.0015 18.5 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Septin PF00735.18 PSC70745.1 - 0.013 14.8 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Septin DUF87 PF01935.17 PSC70745.1 - 0.043 13.9 0.9 0.16 12.0 0.1 2.2 2 0 0 2 2 2 0 Helicase HerA, central domain GerD PF17898.1 PSC70745.1 - 1.5 8.8 7.7 9.6 6.2 7.7 2.2 1 1 0 1 1 1 0 Spore germination GerD central core domain NMT PF01233.19 PSC70746.1 - 3.2e-79 264.4 0.0 4.4e-79 263.9 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 PSC70746.1 - 2e-71 239.8 0.0 2.9e-71 239.3 0.0 1.2 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.7 PSC70746.1 - 0.00026 21.1 0.0 0.00089 19.3 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PSC70746.1 - 0.0016 18.7 0.0 0.0034 17.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PSC70746.1 - 0.054 13.4 0.0 0.26 11.3 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glyoxalase PF00903.25 PSC70747.1 - 3e-10 40.4 0.0 4.3e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 PSC70747.1 - 2.3e-06 27.9 0.0 3.5e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 PSC70747.1 - 7.7e-05 23.4 0.0 0.00015 22.5 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 PSC70747.1 - 0.0002 21.5 0.0 0.00035 20.7 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain LSM PF01423.22 PSC70748.1 - 8.1e-16 57.5 0.0 1.3e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 PSC70748.1 - 0.0012 18.9 0.0 0.002 18.2 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain His_Phos_1 PF00300.22 PSC70749.1 - 4.1e-11 42.9 0.0 5.8e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) PHF5 PF03660.14 PSC70750.1 - 3.8e-49 165.2 12.4 5.1e-49 164.8 12.4 1.2 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 PSC70750.1 - 0.49 8.2 6.7 0.63 7.8 6.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Adenine_deam_C PF13382.6 PSC70751.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Adenine deaminase C-terminal domain Peptidase_S41 PF03572.18 PSC70752.1 - 2.1e-45 154.3 0.0 3.2e-45 153.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 PSC70752.1 - 1.1e-15 57.2 0.6 2.4e-15 56.1 0.6 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PSC70752.1 - 2.5e-09 37.3 0.1 5.5e-09 36.2 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 PSC70752.1 - 2.3e-08 34.3 0.2 4.8e-08 33.2 0.2 1.5 1 0 0 1 1 1 1 PDZ domain DUF952 PF06108.12 PSC70753.1 - 3.1e-17 62.3 0.1 8.2e-17 61.0 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF952) CxC5 PF18718.1 PSC70753.1 - 0.037 14.1 0.0 0.056 13.5 0.0 1.2 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases Glyco_hydro_1 PF00232.18 PSC70754.1 - 3e-61 207.2 0.4 1.1e-60 205.3 0.4 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 1 TPM_phosphatase PF04536.14 PSC70754.1 - 1.2e-20 73.9 0.0 3e-20 72.6 0.0 1.5 1 0 0 1 1 1 1 TPM domain MOLO1 PF17175.4 PSC70754.1 - 1.4e-16 60.7 0.0 2.5e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 Modulator of levamisole receptor-1 zf-RING_2 PF13639.6 PSC70754.1 - 2.3e-10 40.7 6.0 7.1e-08 32.7 3.9 2.8 2 0 0 2 2 2 2 Ring finger domain zf-C3HC4_3 PF13920.6 PSC70754.1 - 1.1e-07 31.5 1.7 1.1e-07 31.5 1.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC70754.1 - 2.6e-07 30.4 6.2 3e-07 30.2 1.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PSC70754.1 - 3.6e-07 30.4 1.3 3.6e-07 30.4 1.3 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 PSC70754.1 - 5.2e-07 29.4 4.0 5.2e-07 29.4 4.0 2.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC70754.1 - 1.6e-06 28.0 1.5 1.6e-06 28.0 1.5 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PSC70754.1 - 5.4e-06 26.3 11.0 0.00014 21.8 4.5 3.0 2 0 0 2 2 2 2 RING-type zinc-finger Prok-RING_4 PF14447.6 PSC70754.1 - 2.9e-05 23.8 1.9 2.9e-05 23.8 1.9 2.4 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Cellulase PF00150.18 PSC70754.1 - 8.4e-05 22.1 0.0 0.0016 17.9 0.0 2.2 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) zf-C3HC4_4 PF15227.6 PSC70754.1 - 0.00016 21.8 3.5 0.00016 21.8 3.5 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 PSC70754.1 - 0.0029 17.4 1.1 0.0085 15.9 1.1 1.7 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 PSC70754.1 - 0.011 15.8 0.3 0.035 14.1 0.3 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Glyco_hydro_10 PF00331.20 PSC70754.1 - 0.079 12.1 0.0 1.2 8.2 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 10 zf-RING_4 PF14570.6 PSC70754.1 - 0.49 10.2 7.5 0.075 12.8 2.4 2.1 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 PSC70754.1 - 1.1 9.0 3.9 0.31 10.7 0.4 2.0 2 0 0 2 2 1 0 P-11 zinc finger zf-RING_11 PF17123.5 PSC70754.1 - 4.3 7.2 7.7 5.2 6.9 0.3 2.9 3 0 0 3 3 3 0 RING-like zinc finger ABC1 PF03109.16 PSC70755.1 - 1.3e-31 109.2 0.0 2.8e-31 108.1 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 PSC70755.1 - 0.0026 17.2 0.0 0.17 11.3 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 PSC70755.1 - 0.0078 16.2 0.0 0.0078 16.2 0.0 4.2 3 2 0 3 3 3 1 Phosphotransferase enzyme family eIF-3_zeta PF05091.12 PSC70756.1 - 0.78 8.6 6.3 1.1 8.1 6.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RRM_1 PF00076.22 PSC70758.1 - 4e-06 26.5 0.0 0.00013 21.7 0.0 2.3 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GlutR_dimer PF00745.20 PSC70759.1 - 0.0049 17.3 3.7 1.4 9.4 0.5 2.5 2 1 0 2 2 2 2 Glutamyl-tRNAGlu reductase, dimerisation domain DUF4913 PF16259.5 PSC70759.1 - 0.045 13.8 0.1 0.1 12.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4913) Sigma54_CBD PF04963.13 PSC70759.1 - 0.047 13.5 0.1 0.088 12.7 0.1 1.4 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain Cep57_CLD_2 PF14197.6 PSC70759.1 - 0.096 12.8 0.1 0.096 12.8 0.1 2.6 4 0 0 4 4 4 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 PSC70759.1 - 3.9 8.0 7.3 0.45 11.0 1.3 2.4 3 0 0 3 3 3 0 Cell division protein ZapB SlyX PF04102.12 PSC70759.1 - 4.7 7.9 6.6 0.91 10.2 1.8 2.3 3 0 0 3 3 3 0 SlyX HMG_box_2 PF09011.10 PSC70760.1 - 4.3e-05 24.0 0.5 7.9e-05 23.2 0.5 1.4 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 PSC70760.1 - 0.00042 20.7 0.2 0.00082 19.7 0.2 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box Trypsin PF00089.26 PSC70761.1 - 1.8e-27 96.6 0.0 3.2e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PSC70761.1 - 0.00064 20.7 0.0 0.0026 18.7 0.0 2.0 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 PSC70762.1 - 1.6e-32 113.1 0.0 2.2e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Trypsin LRR_8 PF13855.6 PSC70762.1 - 4.7e-08 32.7 13.3 0.0068 16.1 0.7 6.6 6 1 0 6 6 6 3 Leucine rich repeat LRR_4 PF12799.7 PSC70762.1 - 1e-06 29.0 6.6 0.032 14.6 0.0 6.9 3 2 6 9 9 9 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 PSC70762.1 - 0.0012 18.7 0.0 0.0045 16.8 0.0 2.0 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.6 PSC70762.1 - 0.0054 16.7 19.0 5.1 7.4 0.2 8.8 11 0 0 11 11 11 3 Leucine Rich repeat Trypsin_2 PF13365.6 PSC70762.1 - 0.0084 17.0 0.0 0.026 15.4 0.0 1.9 1 1 0 1 1 1 1 Trypsin-like peptidase domain LRR_1 PF00560.33 PSC70762.1 - 3.5 8.6 11.2 1.7 9.5 0.5 5.7 7 1 0 7 7 7 0 Leucine Rich Repeat E1-E2_ATPase PF00122.20 PSC70763.1 - 1.1e-43 148.9 2.0 1.1e-43 148.9 2.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 PSC70763.1 - 5.8e-41 140.2 2.1 2.1e-19 69.9 0.0 3.2 3 1 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 PSC70763.1 - 2.6e-23 83.4 0.0 3.4e-18 66.7 0.1 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PSC70763.1 - 2.3e-16 59.6 0.0 4.5e-16 58.7 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 PSC70763.1 - 7.4e-15 54.4 0.0 2e-14 53.0 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PSC70763.1 - 2.6e-06 27.4 0.6 0.00031 20.6 0.4 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 PSC70763.1 - 0.013 15.9 0.2 0.043 14.2 0.3 1.8 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase MCD PF05292.11 PSC70764.1 - 3e-77 259.7 0.0 3e-77 259.7 0.0 4.2 2 2 1 3 3 3 1 Malonyl-CoA decarboxylase C-terminal domain DUF1664 PF07889.12 PSC70764.1 - 0.0014 18.7 0.5 0.0029 17.6 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Tweety PF04906.13 PSC70764.1 - 0.11 11.1 0.5 0.17 10.5 0.5 1.2 1 0 0 1 1 1 0 Tweety Prominin PF05478.11 PSC70764.1 - 0.16 9.9 0.3 0.24 9.3 0.3 1.1 1 0 0 1 1 1 0 Prominin MCD PF05292.11 PSC70765.1 - 3e-77 259.7 0.0 3e-77 259.7 0.0 4.2 2 2 1 3 3 3 1 Malonyl-CoA decarboxylase C-terminal domain DUF1664 PF07889.12 PSC70765.1 - 0.0014 18.7 0.5 0.003 17.6 0.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1664) Tweety PF04906.13 PSC70765.1 - 0.11 11.1 0.5 0.17 10.5 0.5 1.2 1 0 0 1 1 1 0 Tweety Prominin PF05478.11 PSC70765.1 - 0.16 9.9 0.3 0.24 9.3 0.3 1.1 1 0 0 1 1 1 0 Prominin Phosducin PF02114.16 PSC70766.1 - 8.9e-14 51.1 0.0 1.2e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 Phosducin Dermcidin PF15291.6 PSC70766.1 - 0.17 12.4 0.2 0.17 12.4 0.2 1.9 2 0 0 2 2 2 0 Dermcidin, antibiotic peptide Gpr1_Fun34_YaaH PF01184.19 PSC70767.1 - 1.2e-17 64.2 18.6 2.6e-17 63.1 18.6 1.5 1 1 0 1 1 1 1 GPR1/FUN34/yaaH family Sacchrp_dh_NADP PF03435.18 PSC70768.1 - 3.4e-15 56.5 0.0 6.8e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 PSC70768.1 - 0.0044 16.9 0.7 0.011 15.7 0.7 1.6 1 0 0 1 1 1 1 NAD(P)H-binding Dsh_C PF12316.8 PSC70768.1 - 0.1 13.0 0.1 0.21 12.0 0.1 1.5 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Ldh_1_N PF00056.23 PSC70768.1 - 0.31 11.1 0.6 0.52 10.4 0.0 1.6 2 0 0 2 2 2 0 lactate/malate dehydrogenase, NAD binding domain Ribosomal_60s PF00428.19 PSC70769.1 - 7.2 7.3 22.5 16 6.1 0.7 2.3 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ephrin_rec_like PF07699.13 PSC70770.1 - 4.9e-63 208.7 284.4 9.8e-08 31.6 4.7 31.5 14 9 18 32 32 32 25 Putative ephrin-receptor like DUF647 PF04884.14 PSC70770.1 - 1.9e-61 207.8 0.7 3.1e-61 207.1 0.7 1.3 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis tRNA-synt_His PF13393.6 PSC70770.1 - 1.9e-45 155.5 0.0 3.1e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase NCD3G PF07562.14 PSC70770.1 - 2.4e-08 33.8 198.2 0.0066 16.4 0.9 24.4 18 7 8 28 28 28 13 Nine Cysteines Domain of family 3 GPCR tRNA-synt_2b PF00587.25 PSC70770.1 - 5.8e-08 32.9 0.0 9.8e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 PSC70770.1 - 1.1e-05 25.4 0.0 2.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.20 PSC70770.1 - 0.22 10.9 0.0 0.42 10.1 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Ephrin_rec_like PF07699.13 PSC70771.1 - 6.3e-63 208.3 284.3 9.9e-08 31.6 4.7 31.5 14 9 17 31 31 31 25 Putative ephrin-receptor like DUF647 PF04884.14 PSC70771.1 - 1.9e-61 207.8 0.7 3.1e-61 207.1 0.7 1.3 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis tRNA-synt_His PF13393.6 PSC70771.1 - 2e-45 155.4 0.0 3.2e-45 154.8 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase NCD3G PF07562.14 PSC70771.1 - 1.7e-08 34.3 197.3 0.0055 16.6 0.7 24.4 18 7 6 27 27 27 13 Nine Cysteines Domain of family 3 GPCR tRNA-synt_2b PF00587.25 PSC70771.1 - 5.9e-08 32.9 0.0 1e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 PSC70771.1 - 1.2e-05 25.4 0.0 2.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2d PF01409.20 PSC70771.1 - 0.23 10.9 0.0 0.42 10.0 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Myb_DNA-binding PF00249.31 PSC70772.1 - 3.5e-12 46.3 1.3 5.7e-12 45.6 1.3 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PSC70772.1 - 0.0084 16.0 0.5 0.018 14.9 0.5 1.5 1 0 0 1 1 1 1 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 PSC70772.1 - 0.025 14.8 0.8 0.043 14.1 0.8 1.3 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 PSC70773.1 - 0.00026 21.1 0.0 0.00026 21.1 0.0 1.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Abhydrolase_5 PF12695.7 PSC70775.1 - 0.0059 16.4 0.0 0.33 10.7 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PSC70775.1 - 0.0065 15.8 0.3 0.64 9.2 0.6 2.9 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 PSC70775.1 - 0.035 14.2 1.2 0.036 14.2 0.2 1.6 2 0 0 2 2 2 0 Thioesterase domain Abhydrolase_6 PF12697.7 PSC70775.1 - 0.039 14.6 17.2 0.084 13.5 17.2 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF3089 PF11288.8 PSC70775.1 - 0.049 13.2 0.4 1.9 8.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3089) Lipase_3 PF01764.25 PSC70775.1 - 0.17 11.7 0.0 0.32 10.9 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 PSC70775.1 - 0.2 11.4 0.0 0.67 9.6 0.0 1.8 2 0 0 2 2 2 0 PGAP1-like protein PG_binding_1 PF01471.18 PSC70776.1 - 6.9e-17 61.4 0.0 4.4e-08 33.2 0.0 2.8 2 0 0 2 2 2 2 Putative peptidoglycan binding domain PG_binding_2 PF08823.11 PSC70776.1 - 0.018 15.3 0.1 4.2 7.7 0.0 3.0 3 0 0 3 3 3 0 Putative peptidoglycan binding domain SR-25 PF10500.9 PSC70776.1 - 7.4 6.1 7.7 13 5.3 7.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Actin PF00022.19 PSC70778.1 - 8.5e-82 274.9 0.0 1.3e-50 172.2 0.0 2.0 1 1 1 2 2 2 2 Actin FtsA PF14450.6 PSC70778.1 - 0.0019 18.6 0.0 0.0046 17.4 0.0 1.8 2 0 0 2 2 2 1 Cell division protein FtsA MreB_Mbl PF06723.13 PSC70778.1 - 0.0032 16.4 0.0 0.0091 14.9 0.0 1.7 2 1 0 2 2 2 1 MreB/Mbl protein BolA PF01722.18 PSC70779.1 - 6.6e-33 112.8 0.1 8.6e-33 112.4 0.1 1.2 1 0 0 1 1 1 1 BolA-like protein RINGv PF12906.7 PSC70780.1 - 2e-06 27.8 8.4 3.1e-06 27.2 8.4 1.3 1 0 0 1 1 1 1 RING-variant domain Zf_RING PF16744.5 PSC70780.1 - 0.059 13.5 2.0 0.13 12.4 2.0 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 PSC70780.1 - 0.19 11.4 5.0 0.28 10.8 3.0 2.0 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 PSC70780.1 - 1 9.7 8.3 2 8.8 8.3 1.5 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.29 PSC70780.1 - 1.1 9.2 5.5 2.2 8.3 5.5 1.5 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 PSC70781.1 - 1.8e-06 28.0 8.4 2.9e-06 27.3 8.4 1.3 1 0 0 1 1 1 1 RING-variant domain Zf_RING PF16744.5 PSC70781.1 - 0.054 13.6 2.0 0.12 12.5 2.0 1.6 1 0 0 1 1 1 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 PSC70781.1 - 0.16 11.6 4.9 1.1 9.0 5.1 2.0 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 PSC70781.1 - 0.94 9.9 8.3 1.8 8.9 8.3 1.5 1 0 0 1 1 1 0 Ring finger domain PHD PF00628.29 PSC70781.1 - 1 9.3 5.5 2 8.4 5.5 1.5 1 0 0 1 1 1 0 PHD-finger W2 PF02020.18 PSC70782.1 - 0.084 13.0 0.4 0.14 12.3 0.4 1.4 1 0 0 1 1 1 0 eIF4-gamma/eIF5/eIF2-epsilon mit_SMPDase PF14724.6 PSC70783.1 - 1.1e-09 36.9 0.0 0.0012 17.0 0.0 3.8 4 0 0 4 4 4 3 Mitochondrial-associated sphingomyelin phosphodiesterase Ribonuc_2-5A PF06479.12 PSC70783.1 - 0.17 12.1 0.0 0.32 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease 2-5A H2TH PF06831.14 PSC70784.1 - 1.6e-23 82.5 0.0 2.8e-23 81.7 0.0 1.3 1 0 0 1 1 1 1 Formamidopyrimidine-DNA glycosylase H2TH domain Fapy_DNA_glyco PF01149.24 PSC70784.1 - 5.6e-13 49.5 0.1 1.9e-12 47.9 0.0 1.9 2 0 0 2 2 2 1 Formamidopyrimidine-DNA glycosylase N-terminal domain FbpA PF05833.11 PSC70784.1 - 0.022 13.5 0.0 0.03 13.1 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) Radical_SAM PF04055.21 PSC70785.1 - 3.4e-12 47.1 0.0 6.5e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 PSC70785.1 - 0.001 19.2 1.2 0.0017 18.5 0.0 1.8 2 0 0 2 2 1 1 4Fe-4S single cluster domain CDC45 PF02724.14 PSC70785.1 - 0.11 10.7 2.1 0.16 10.2 2.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF3464 PF11947.8 PSC70785.1 - 0.19 11.4 1.2 0.31 10.8 1.2 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Myc_N PF01056.18 PSC70785.1 - 0.2 11.5 4.9 0.29 11.0 4.9 1.1 1 0 0 1 1 1 0 Myc amino-terminal region ORC6 PF05460.13 PSC70785.1 - 0.24 10.7 4.7 0.36 10.0 4.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ndc1_Nup PF09531.10 PSC70785.1 - 0.25 10.0 0.9 0.34 9.5 0.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 PSC70785.1 - 0.31 9.7 3.8 0.42 9.3 3.8 1.1 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 PSC70785.1 - 0.44 10.1 16.7 2.9 7.5 18.3 1.5 2 0 0 2 2 2 0 Spt20 family Pox_Ag35 PF03286.14 PSC70785.1 - 0.89 9.3 5.1 1.4 8.7 5.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF908 PF06012.12 PSC70785.1 - 1.1 8.5 3.3 2 7.8 3.3 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) CCDC53 PF10152.9 PSC70785.1 - 1.5 9.2 7.3 2.4 8.5 7.3 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Suf PF05843.14 PSC70785.1 - 2.5 8.0 6.9 3.6 7.5 6.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RR_TM4-6 PF06459.12 PSC70785.1 - 2.5 7.8 5.6 3.6 7.3 5.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 PSC70785.1 - 4.4 6.2 6.8 1.3 8.0 3.6 1.6 2 0 0 2 2 2 0 Solute carrier family 12 DUF4834 PF16118.5 PSC70785.1 - 6.8 7.7 7.8 12 6.9 7.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CobT PF06213.12 PSC70785.1 - 7.4 5.9 16.4 12 5.2 16.4 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT V_ATPase_I PF01496.19 PSC70785.1 - 8.6 4.1 6.7 11 3.8 6.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family cobW PF02492.19 PSC70787.1 - 6.1e-34 117.1 0.0 9.8e-34 116.5 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 PSC70787.1 - 0.0015 18.4 0.0 0.0038 17.1 0.0 1.8 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain Gly-rich_Ago1 PF12764.7 PSC70787.1 - 0.031 15.1 3.8 0.031 15.1 3.8 2.7 3 0 0 3 3 3 0 Glycine-rich region of argonaut AAA_16 PF13191.6 PSC70787.1 - 0.24 11.8 4.2 0.94 9.8 0.1 2.7 2 0 0 2 2 2 0 AAA ATPase domain Pkinase PF00069.25 PSC70788.1 - 3.2e-59 200.4 0.0 4.1e-59 200.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC70788.1 - 1e-40 139.7 0.0 1.4e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC70788.1 - 0.002 17.5 0.0 0.0041 16.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 PSC70788.1 - 0.0025 17.8 0.1 0.021 14.7 0.0 2.3 2 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 PSC70788.1 - 0.0096 15.3 0.0 0.017 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PSC70788.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SnoaL_2 PF12680.7 PSC70788.1 - 0.084 13.5 0.2 0.41 11.3 0.0 2.2 2 0 0 2 2 2 0 SnoaL-like domain Response_reg PF00072.24 PSC70789.1 - 3e-23 82.1 0.0 5.7e-23 81.2 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.26 PSC70789.1 - 4.1e-13 49.8 0.0 1.6e-09 38.3 0.0 2.4 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 PSC70789.1 - 2.9e-12 46.5 0.0 9.7e-12 44.8 0.0 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain CLLAC PF15675.5 PSC70789.1 - 2.1 8.0 5.2 7 6.3 5.2 1.9 1 0 0 1 1 1 0 CLLAC-motif containing domain Ribosomal_L7Ae PF01248.26 PSC70790.1 - 3e-24 84.6 1.5 5.2e-24 83.8 1.5 1.4 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.11 PSC70790.1 - 0.00049 20.2 0.1 0.00077 19.5 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit Pop3 SHR-BD PF06650.12 PSC70791.1 - 7e-24 84.6 0.0 4.4e-21 75.5 0.0 2.4 2 0 0 2 2 2 2 SHR-binding domain of vacuolar-sorting associated protein 13 C2 PF00168.30 PSC70791.1 - 9.7e-19 67.6 0.0 6.1e-10 39.3 0.0 2.4 2 0 0 2 2 2 2 C2 domain VPS13 PF16908.5 PSC70791.1 - 2.7e-06 27.4 0.0 5.8e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting-associated protein 13, N-terminal ATG_C PF09333.11 PSC70791.1 - 0.0014 18.9 2.4 0.0017 18.6 0.0 2.5 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain VPS13_C PF16909.5 PSC70791.1 - 0.0015 18.3 0.0 0.05 13.4 0.0 2.5 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal tRNA-synt_1g PF09334.11 PSC70792.1 - 1.5e-90 303.8 0.0 7.5e-56 189.6 0.0 2.1 1 1 1 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 PSC70792.1 - 4.7e-19 68.1 0.0 7.1e-11 41.1 0.0 3.9 1 1 2 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 PSC70792.1 - 1.7e-11 44.0 0.0 1.2e-05 24.8 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 PSC70792.1 - 1.3e-07 31.7 0.0 2.8e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA Rieske PF00355.26 PSC70793.1 - 2.8e-17 62.4 0.1 6e-17 61.4 0.1 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 PSC70793.1 - 3.4e-15 56.0 0.0 6.7e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 Pheophorbide a oxygenase Tim17 PF02466.19 PSC70793.1 - 1.4e-13 51.2 8.7 1.4e-13 51.2 8.7 2.0 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family ADIP PF11559.8 PSC70793.1 - 0.085 12.9 8.3 0.18 11.9 8.3 1.5 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding DUF3584 PF12128.8 PSC70793.1 - 0.55 7.7 14.6 0.75 7.2 14.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Mod_r PF07200.13 PSC70793.1 - 4.5 7.4 9.9 3.5 7.7 8.4 1.5 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Fer2_3 PF13085.6 PSC70794.1 - 1.2e-30 105.8 0.1 1.8e-30 105.1 0.1 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 PSC70794.1 - 1.9e-09 37.9 4.4 1.9e-09 37.9 4.4 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 PSC70794.1 - 3.2e-09 37.1 5.3 3.2e-09 37.1 5.3 2.4 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 PSC70794.1 - 1.9e-07 31.1 2.8 1.9e-07 31.1 2.8 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_7 PF12838.7 PSC70794.1 - 0.0001 22.8 5.0 0.0001 22.8 5.0 2.3 2 2 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 PSC70794.1 - 0.00095 19.1 3.2 0.0044 16.9 0.6 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_18 PF13746.6 PSC70794.1 - 0.083 13.1 5.2 0.53 10.5 0.1 2.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 PSC70794.1 - 0.41 10.9 14.6 0.19 11.9 8.8 2.8 2 1 0 2 2 2 0 4Fe-4S dicluster domain KDZ PF18758.1 PSC70795.1 - 4.4e-21 75.5 0.2 7.3e-21 74.8 0.2 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase adh_short PF00106.25 PSC70796.1 - 4.1e-32 111.2 2.4 2.3e-24 86.0 0.8 2.4 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PSC70796.1 - 1.1e-24 87.4 2.8 1.7e-18 67.1 1.6 2.7 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC70796.1 - 4.4e-11 43.0 0.8 4.4e-11 43.0 0.8 2.7 3 0 0 3 3 3 1 KR domain Polysacc_synt_2 PF02719.15 PSC70796.1 - 7.3e-05 22.0 0.0 0.00012 21.3 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 PSC70796.1 - 0.0058 16.1 1.0 0.03 13.8 1.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PSC70796.1 - 0.25 10.7 0.0 0.38 10.1 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Peptidase_S24 PF00717.23 PSC70797.1 - 1.9e-11 43.7 0.0 3.2e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Peptidase S24-like Bombesin PF02044.17 PSC70797.1 - 0.21 11.7 0.6 0.51 10.5 0.6 1.7 1 0 0 1 1 1 0 Bombesin-like peptide PDZ_1 PF12812.7 PSC70799.1 - 2.7e-28 97.8 0.0 8.4e-15 54.6 0.0 3.4 3 0 0 3 3 3 2 PDZ-like domain Trypsin_2 PF13365.6 PSC70799.1 - 3.2e-21 76.8 0.3 1.5e-19 71.4 0.1 2.9 2 0 0 2 2 2 1 Trypsin-like peptidase domain PDZ_2 PF13180.6 PSC70799.1 - 1.2e-18 67.2 0.0 4.2e-07 30.2 0.0 5.3 5 0 0 5 5 5 3 PDZ domain PDZ_6 PF17820.1 PSC70799.1 - 7.3e-17 61.0 1.5 0.00059 19.6 0.3 4.7 4 0 0 4 4 4 3 PDZ domain PDZ PF00595.24 PSC70799.1 - 1.2e-11 44.8 0.0 0.016 15.5 0.0 3.6 3 0 0 3 3 3 3 PDZ domain Peptidase_S46 PF10459.9 PSC70799.1 - 6.2e-05 21.9 3.1 0.00057 18.7 0.0 2.8 3 0 0 3 3 3 1 Peptidase S46 TFIIA PF03153.13 PSC70799.1 - 0.00074 19.6 7.4 0.0013 18.8 7.4 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Trypsin PF00089.26 PSC70799.1 - 0.0014 18.5 0.0 0.0044 16.8 0.0 1.7 1 1 0 1 1 1 1 Trypsin DUF2722 PF10846.8 PSC70799.1 - 0.0018 17.3 7.0 0.0025 16.8 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Tricorn_PDZ PF14685.6 PSC70799.1 - 0.0047 16.9 0.0 6.8 6.7 0.0 3.7 4 0 0 4 4 4 1 Tricorn protease PDZ domain Peptidase_S7 PF00949.21 PSC70799.1 - 0.0073 16.1 0.5 0.016 15.1 0.5 1.4 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease CDRT4 PF15213.6 PSC70799.1 - 0.18 12.4 1.4 0.35 11.5 1.4 1.4 1 0 0 1 1 1 0 CMT1A duplicated region transcript 4 protein Spt20 PF12090.8 PSC70799.1 - 0.19 11.3 17.1 0.31 10.6 17.1 1.2 1 0 0 1 1 1 0 Spt20 family HABP4_PAI-RBP1 PF04774.15 PSC70799.1 - 0.34 11.8 5.3 0.76 10.6 5.3 1.5 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family DUF31 PF01732.16 PSC70799.1 - 0.57 9.7 3.2 0.16 11.5 0.1 1.5 2 0 0 2 2 2 0 Putative peptidase (DUF31) Suf PF05843.14 PSC70799.1 - 0.99 9.3 4.3 1.7 8.5 4.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF4834 PF16118.5 PSC70799.1 - 1.3 10.1 3.3 2.5 9.1 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) STAG PF08514.11 PSC70800.1 - 3.2e-17 62.5 0.0 1e-16 60.8 0.0 1.9 1 0 0 1 1 1 1 STAG domain HEAT PF02985.22 PSC70800.1 - 8e-05 22.6 13.8 0.21 12.0 0.2 6.3 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.6 PSC70800.1 - 0.0005 20.4 28.6 0.0006 20.2 0.1 6.3 6 0 0 6 6 6 2 HEAT repeats Adaptin_N PF01602.20 PSC70800.1 - 0.0017 17.0 0.5 0.0033 16.1 0.0 1.6 2 0 0 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 PSC70800.1 - 0.011 15.7 0.0 0.27 11.3 0.0 2.6 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Topoisom_bac PF01131.20 PSC70801.1 - 8.9e-101 337.9 0.0 2.9e-67 227.5 0.0 2.5 2 0 0 2 2 2 2 DNA topoisomerase PRK PF00485.18 PSC70801.1 - 4.1e-23 82.2 0.4 3e-22 79.3 0.4 2.2 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Toprim PF01751.22 PSC70801.1 - 6.5e-20 71.3 0.0 1.6e-19 70.0 0.0 1.7 1 0 0 1 1 1 1 Toprim domain Toprim_C_rpt PF13368.6 PSC70801.1 - 2.9e-19 68.8 0.0 4.9e-08 32.8 0.0 3.2 2 0 0 2 2 2 2 Topoisomerase C-terminal repeat CYTH PF01928.21 PSC70801.1 - 4.3e-14 52.9 0.0 1.1e-13 51.5 0.0 1.7 1 0 0 1 1 1 1 CYTH domain HMG_box_2 PF09011.10 PSC70801.1 - 1.6e-13 51.0 3.7 1.5e-06 28.7 0.2 2.8 2 0 0 2 2 2 2 HMG-box domain HMG_box PF00505.19 PSC70801.1 - 3.1e-09 37.1 3.5 0.00025 21.4 0.6 2.9 2 0 0 2 2 2 2 HMG (high mobility group) box zf-C4_Topoisom PF01396.19 PSC70801.1 - 7.9e-09 35.2 3.6 9.1e-09 35.0 0.9 2.6 3 0 0 3 3 3 1 Topoisomerase DNA binding C4 zinc finger CTP_transf_like PF01467.26 PSC70801.1 - 0.00012 22.3 0.0 0.00039 20.6 0.0 2.0 1 0 0 1 1 1 1 Cytidylyltransferase-like AJAP1_PANP_C PF15298.6 PSC70801.1 - 0.13 12.4 0.7 0.88 9.7 0.0 2.3 2 0 0 2 2 2 0 AJAP1/PANP C-terminus NB-ARC PF00931.22 PSC70801.1 - 0.23 10.6 0.0 0.42 9.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Tropomodulin PF03250.14 PSC70801.1 - 0.49 10.4 2.5 0.49 10.4 0.7 1.9 2 0 0 2 2 2 0 Tropomodulin Cation_ATPase_C PF00689.21 PSC70802.1 - 4.4e-48 163.4 1.0 9e-48 162.4 1.0 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 PSC70802.1 - 5.6e-48 162.9 1.4 5.6e-48 162.9 1.4 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 PSC70802.1 - 9.3e-21 75.1 0.1 3.9e-16 60.0 0.0 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PSC70802.1 - 2.2e-19 68.9 1.9 5.2e-19 67.7 0.1 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 PSC70802.1 - 1.7e-17 63.3 0.0 3.3e-17 62.3 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) HAD PF12710.7 PSC70802.1 - 2.1e-06 28.2 0.1 6.1e-06 26.8 0.1 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 PSC70802.1 - 0.00016 21.5 1.9 0.0017 18.1 1.6 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase MoeA_N PF03453.17 PSC70802.1 - 0.0033 17.2 0.1 0.008 16.0 0.1 1.6 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) SpoVIF PF14069.6 PSC70803.1 - 0.23 11.3 0.0 0.39 10.5 0.0 1.3 1 0 0 1 1 1 0 Stage VI sporulation protein F bZIP_1 PF00170.21 PSC70804.1 - 0.00048 20.2 9.0 0.00048 20.2 9.0 1.7 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 PSC70804.1 - 0.0025 17.9 10.0 0.0025 17.9 10.0 1.7 2 0 0 2 2 2 1 Basic region leucine zipper CENP-F_leu_zip PF10473.9 PSC70804.1 - 0.072 13.1 6.7 0.15 12.1 6.7 1.4 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 CSTF_C PF14304.6 PSC70804.1 - 0.19 11.4 1.1 16 5.1 0.2 2.8 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal GAS PF13851.6 PSC70804.1 - 3.4 7.0 13.2 0.15 11.4 7.0 1.8 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Acyltransferase PF01553.21 PSC70805.1 - 5.5e-22 77.8 0.0 8.8e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase HAUS6_N PF14661.6 PSC70806.1 - 4.5e-11 42.8 0.0 8.9e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 6 N-terminus tRNA-synt_2d PF01409.20 PSC70806.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) S-AdoMet_synt_C PF02773.16 PSC70807.1 - 1.2e-61 206.7 0.1 2.3e-61 205.8 0.1 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 PSC70807.1 - 1.6e-47 160.7 0.0 3.5e-47 159.6 0.0 1.6 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 PSC70807.1 - 9.4e-43 144.9 0.3 2.6e-42 143.5 0.3 1.8 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain peroxidase PF00141.23 PSC70808.1 - 1.8e-49 168.5 0.0 2.8e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Peroxidase DUF1972 PF09314.11 PSC70808.1 - 0.071 12.7 0.2 0.11 12.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1972) ATP-sulfurylase PF01747.17 PSC70809.1 - 1.8e-69 233.4 0.0 3e-69 232.7 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 PSC70809.1 - 5.2e-39 133.5 0.0 7.4e-39 133.0 0.0 1.2 1 0 0 1 1 1 1 PUA-like domain DUF4772 PF15997.5 PSC70809.1 - 0.007 17.0 0.0 0.018 15.7 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4772) FMN_red PF03358.15 PSC70809.1 - 0.058 13.1 0.0 0.19 11.5 0.0 1.8 2 0 0 2 2 2 0 NADPH-dependent FMN reductase Polyketide_cyc PF03364.20 PSC70811.1 - 0.043 14.0 1.2 0.06 13.5 0.2 1.9 2 1 0 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport Complex1_LYR PF05347.15 PSC70812.1 - 3.3e-09 36.7 0.2 6.5e-09 35.7 0.2 1.5 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Rhomboid PF01694.22 PSC70813.1 - 2.3e-18 66.7 6.7 4.9e-18 65.6 6.7 1.6 1 0 0 1 1 1 1 Rhomboid family U-box PF04564.15 PSC70813.1 - 2.5e-18 66.0 0.0 5e-18 65.0 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.6 PSC70813.1 - 0.00035 20.5 0.1 0.0014 18.6 0.1 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PSC70813.1 - 0.0084 15.9 0.0 0.016 15.1 0.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC70813.1 - 0.086 13.2 0.0 0.18 12.2 0.0 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4_4 PF15227.6 PSC70813.1 - 0.11 12.7 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 PSC70813.1 - 0.18 12.1 0.0 0.43 10.9 0.0 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain SirB PF04247.12 PSC70813.1 - 0.4 10.8 6.7 0.57 10.3 2.3 2.2 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB DUF2070 PF09843.9 PSC70813.1 - 0.83 7.9 1.3 1.3 7.2 1.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Urb2 PF10441.9 PSC70814.1 - 6.9e-19 68.6 0.0 6.9e-19 68.6 0.0 2.9 5 0 0 5 5 5 1 Urb2/Npa2 family Polysacc_deac_1 PF01522.21 PSC70814.1 - 1.5e-11 44.3 0.0 3.4e-11 43.1 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide deacetylase SAM_Exu PF18609.1 PSC70814.1 - 0.046 13.8 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Exuperantia SAM-like domain NifQ PF04891.12 PSC70814.1 - 5.8 7.2 8.0 3.7 7.9 2.7 3.1 2 0 0 2 2 2 0 NifQ Prenyltransf PF01255.19 PSC70815.1 - 6.6e-72 241.7 0.0 8.6e-72 241.3 0.0 1.1 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Spt20 PF12090.8 PSC70815.1 - 1.9 8.0 5.2 50 3.4 6.0 2.0 2 0 0 2 2 2 0 Spt20 family TFIIA PF03153.13 PSC70815.1 - 4.8 7.1 13.0 7.1 6.5 13.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2761 PF10959.8 PSC70816.1 - 0.11 12.5 0.4 0.4 10.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2761) ACPS PF01648.20 PSC70818.1 - 5.7e-14 52.2 0.0 1.5e-13 50.9 0.0 1.7 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily AF-4 PF05110.13 PSC70818.1 - 0.38 8.8 6.2 0.46 8.5 6.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PAN_4 PF14295.6 PSC70819.1 - 3.4e-11 42.9 17.4 4.9e-07 29.6 3.2 3.6 3 0 0 3 3 3 2 PAN domain FH2 PF02181.23 PSC70820.1 - 2.7e-23 82.7 0.0 3.4e-23 82.4 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Abhydrolase_1 PF00561.20 PSC70821.1 - 5.7e-17 62.2 0.0 8.1e-14 51.9 0.0 2.1 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC70821.1 - 1.2e-15 57.4 0.0 8.1e-10 38.4 0.0 2.1 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 PSC70821.1 - 0.00024 20.6 0.0 0.0043 16.6 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF1749 PF08538.10 PSC70821.1 - 0.0032 16.6 0.0 0.17 10.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Abhydrolase_5 PF12695.7 PSC70821.1 - 0.014 15.1 0.0 1.8 8.3 0.0 2.4 3 0 0 3 3 3 0 Alpha/beta hydrolase family UvrA_DNA-bind PF17755.1 PSC70821.1 - 0.016 15.5 0.0 0.049 14.0 0.0 1.6 1 1 1 2 2 2 0 UvrA DNA-binding domain Alfin PF12165.8 PSC70821.1 - 0.018 14.7 0.0 0.67 9.6 0.0 2.2 2 0 0 2 2 2 0 Alfin DUF2974 PF11187.8 PSC70821.1 - 0.021 14.4 0.0 2.4 7.7 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) DUF915 PF06028.11 PSC70821.1 - 0.032 13.6 0.0 0.45 9.8 0.0 2.2 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) VirJ PF06057.11 PSC70821.1 - 0.11 12.3 0.0 2.3 8.1 0.0 2.2 2 0 0 2 2 2 0 Bacterial virulence protein (VirJ) Esterase PF00756.20 PSC70821.1 - 0.13 11.9 0.0 0.2 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative esterase YCII PF03795.14 PSC70823.1 - 1.5e-08 34.9 0.0 2e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 YCII-related domain Sugar_tr PF00083.24 PSC70824.1 - 1.5e-76 258.1 16.8 6.2e-46 157.2 2.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 PSC70824.1 - 2.1e-14 53.2 46.0 3.8e-12 45.8 15.9 2.2 2 0 0 2 2 2 2 Major Facilitator Superfamily Tli4_C PF18426.1 PSC70824.1 - 0.13 12.5 1.0 0.28 11.5 0.3 1.8 2 0 0 2 2 2 0 Tle cognate immunity protein 4 C-terminal domain DUF2070 PF09843.9 PSC70824.1 - 2.4 6.4 9.8 4.3 5.5 9.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Sugar_tr PF00083.24 PSC70825.1 - 6e-83 279.2 18.1 6.6e-46 157.1 2.0 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 PSC70825.1 - 1.4e-15 57.1 48.2 3.2e-12 46.0 15.6 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily OATP PF03137.20 PSC70825.1 - 0.12 10.7 0.9 10 4.2 1.0 2.4 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Tli4_C PF18426.1 PSC70825.1 - 0.14 12.5 1.0 0.29 11.4 0.3 1.8 2 0 0 2 2 2 0 Tle cognate immunity protein 4 C-terminal domain DUF2070 PF09843.9 PSC70825.1 - 7.4 4.7 12.3 13 3.9 12.3 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PQ-loop PF04193.14 PSC70826.1 - 1.9e-22 78.8 4.3 7.8e-11 41.6 2.5 2.6 2 0 0 2 2 2 2 PQ loop repeat DUF572 PF04502.13 PSC70827.1 - 2.6e-69 234.4 0.1 2.6e-69 234.4 0.1 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF572) Na_Ca_ex PF01699.24 PSC70827.1 - 2.3e-38 131.5 31.9 2.1e-21 76.5 9.2 3.3 3 0 0 3 3 3 2 Sodium/calcium exchanger protein 2OG-FeII_Oxy_3 PF13640.6 PSC70827.1 - 1.3e-17 64.4 0.0 4.4e-17 62.8 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 PSC70827.1 - 1.7e-08 35.0 0.0 4e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-CCCH_4 PF18044.1 PSC70827.1 - 0.055 13.3 8.4 0.012 15.4 3.5 2.5 2 0 0 2 2 2 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 PSC70827.1 - 4.5 7.9 21.9 3.3 8.3 3.7 3.8 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 PSC70827.1 - 5.7 7.0 15.1 3.4 7.7 4.1 3.6 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF572 PF04502.13 PSC70828.1 - 1.4e-69 235.3 0.1 2.3e-69 234.5 0.1 1.3 1 0 0 1 1 1 1 Family of unknown function (DUF572) Na_Ca_ex PF01699.24 PSC70828.1 - 1.8e-38 131.9 31.9 2e-21 76.6 9.2 3.3 3 0 0 3 3 3 2 Sodium/calcium exchanger protein 2OG-FeII_Oxy_3 PF13640.6 PSC70828.1 - 1.2e-17 64.6 0.0 4.1e-17 62.9 0.0 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 PSC70828.1 - 1.7e-08 35.0 0.0 3.8e-08 33.9 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf-CCCH_4 PF18044.1 PSC70828.1 - 0.047 13.5 8.4 0.011 15.5 3.5 2.6 2 0 0 2 2 2 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 PSC70828.1 - 3.5 8.2 21.9 3.1 8.4 3.7 3.8 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 PSC70828.1 - 4.5 7.3 15.1 3.2 7.8 4.1 3.7 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TMF_DNA_bd PF12329.8 PSC70829.1 - 4.5e-15 55.4 5.6 4.5e-15 55.4 5.6 7.9 3 3 4 8 8 8 1 TATA element modulatory factor 1 DNA binding TMF_TATA_bd PF12325.8 PSC70829.1 - 1.4e-13 51.0 9.2 1.4e-13 51.0 9.2 6.8 2 1 4 7 7 7 2 TATA element modulatory factor 1 TATA binding ATG16 PF08614.11 PSC70829.1 - 0.0073 16.6 2.9 0.0073 16.6 2.9 5.6 2 1 3 5 5 4 1 Autophagy protein 16 (ATG16) DUF737 PF05300.11 PSC70829.1 - 0.0098 16.3 1.3 0.0098 16.3 1.3 4.8 2 1 0 2 2 1 1 Protein of unknown function (DUF737) APG6_N PF17675.1 PSC70829.1 - 0.01 16.4 2.7 0.01 16.4 2.7 6.4 2 1 4 6 6 5 0 Apg6 coiled-coil region betaPIX_CC PF16523.5 PSC70829.1 - 0.014 15.2 14.0 0.094 12.6 2.3 4.1 2 1 1 3 3 3 0 betaPIX coiled coil TPR_MLP1_2 PF07926.12 PSC70829.1 - 0.02 14.9 5.4 0.02 14.9 5.4 6.6 3 1 4 7 7 7 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.12 PSC70829.1 - 1.2 9.7 14.1 8.3 7.0 0.1 5.9 5 3 2 7 7 6 0 Nucleopolyhedrovirus P10 protein FliD_C PF07195.12 PSC70829.1 - 5.9 6.2 14.7 5.7 6.3 0.3 4.4 3 1 1 4 4 4 0 Flagellar hook-associated protein 2 C-terminus Surfac_D-trimer PF09006.11 PSC70829.1 - 6 6.8 8.3 32 4.5 1.0 4.4 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation Spc7 PF08317.11 PSC70829.1 - 8.6 5.1 77.5 0.24 10.3 12.1 5.1 2 1 4 6 6 6 0 Spc7 kinetochore protein MBOAT_2 PF13813.6 PSC70830.1 - 2.6e-15 56.5 2.2 5.9e-15 55.3 1.7 1.9 1 1 0 1 1 1 1 Membrane bound O-acyl transferase family 6PF2K PF01591.18 PSC70832.1 - 3.3e-65 219.5 0.0 4.6e-65 219.0 0.0 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 PSC70832.1 - 2.1e-33 115.7 0.0 8.1e-33 113.8 0.0 2.0 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) PseudoU_synth_2 PF00849.22 PSC70832.1 - 1.4e-13 51.2 0.0 7.4e-13 48.9 0.0 2.0 1 1 0 1 1 1 1 RNA pseudouridylate synthase S4 PF01479.25 PSC70832.1 - 3.1e-11 42.8 0.6 6.9e-11 41.7 0.6 1.7 1 0 0 1 1 1 1 S4 domain AAA_33 PF13671.6 PSC70832.1 - 0.0084 16.3 0.0 0.029 14.5 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF2382 PF09557.10 PSC70832.1 - 0.18 12.1 2.6 1.4 9.2 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2382) F-box-like PF12937.7 PSC70833.1 - 1e-07 31.7 3.7 3.8e-07 29.9 1.0 2.5 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PSC70833.1 - 8.9e-06 25.5 2.1 8.9e-06 25.5 2.1 2.0 2 0 0 2 2 2 1 F-box domain TetR_C_6 PF13977.6 PSC70833.1 - 0.0091 16.2 0.2 0.0091 16.2 0.2 2.1 2 0 0 2 2 2 1 BetI-type transcriptional repressor, C-terminal LRR_8 PF13855.6 PSC70833.1 - 0.012 15.4 8.1 0.54 10.1 0.4 5.4 5 2 1 6 6 6 0 Leucine rich repeat LRR_4 PF12799.7 PSC70833.1 - 0.017 15.5 2.8 1.5e+02 3.0 0.0 6.3 4 3 3 7 7 7 0 Leucine Rich repeats (2 copies) adh_short_C2 PF13561.6 PSC70834.1 - 1.2e-51 175.6 5.5 2.1e-49 168.2 5.5 2.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PSC70834.1 - 1.6e-46 158.3 0.8 2.2e-46 157.8 0.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PSC70834.1 - 1.2e-12 48.1 4.3 6.3e-12 45.8 3.3 2.2 2 1 0 2 2 2 1 KR domain 3HCDH_N PF02737.18 PSC70834.1 - 0.009 15.9 0.1 0.015 15.2 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 PSC70834.1 - 0.02 15.0 0.2 0.037 14.1 0.2 1.3 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF1776 PF08643.10 PSC70834.1 - 0.031 13.6 0.0 0.042 13.2 0.0 1.1 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) Glyoxalase PF00903.25 PSC70835.1 - 2.9e-19 69.5 0.0 3.7e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 PSC70835.1 - 6.1e-08 32.9 0.0 0.00015 22.0 0.0 1.9 1 1 1 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 PSC70835.1 - 0.0001 23.0 0.0 0.0003 21.6 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.6 PSC70835.1 - 0.16 12.1 0.0 0.24 11.5 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain DUF3458_C PF17432.2 PSC70836.1 - 6.6e-64 216.3 11.4 4.9e-62 210.2 11.4 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3458_C) ARM repeats Peptidase_M1 PF01433.20 PSC70836.1 - 1.7e-35 122.6 0.0 2.7e-35 121.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M1 domain Trypsin PF00089.26 PSC70836.1 - 1.4e-32 113.3 0.0 2.4e-32 112.6 0.0 1.4 1 0 0 1 1 1 1 Trypsin DUF3458 PF11940.8 PSC70836.1 - 1.1e-23 83.5 0.0 3.7e-23 81.8 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3458) Ig-like fold Peptidase_M1_N PF17900.1 PSC70836.1 - 6.2e-09 36.3 0.0 9.7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain DUF316 PF03761.15 PSC70836.1 - 0.059 12.9 0.0 0.094 12.3 0.0 1.2 1 0 0 1 1 1 0 Chymotrypsin family Peptidase-S1 Peptidase_M16_C PF05193.21 PSC70837.1 - 4.6e-18 65.9 0.0 1.1e-17 64.6 0.0 1.7 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 PSC70837.1 - 1e-14 54.8 0.1 4e-07 30.1 0.0 2.4 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) Xan_ur_permease PF00860.20 PSC70838.1 - 6.5e-81 272.0 32.3 9.6e-81 271.4 32.3 1.2 1 0 0 1 1 1 1 Permease family ATP_bind_1 PF03029.17 PSC70838.1 - 8.8e-73 245.0 0.0 1.2e-72 244.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MeaB PF03308.16 PSC70838.1 - 0.00022 20.3 0.0 0.00038 19.5 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 PSC70838.1 - 0.02 15.0 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 PSC70838.1 - 0.067 12.9 0.0 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 PSC70838.1 - 0.088 13.1 0.0 0.16 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain LRRNT_2 PF08263.12 PSC70840.1 - 3.3e-09 36.9 0.2 6.1e-09 36.0 0.2 1.4 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain TFIID_30kDa PF03540.13 PSC70841.1 - 5.4e-19 67.9 0.0 3.1e-18 65.5 0.0 1.9 2 0 0 2 2 2 1 Transcription initiation factor TFIID 23-30kDa subunit Bromo_TP PF07524.13 PSC70841.1 - 0.041 13.9 0.0 5.3 7.1 0.0 2.6 1 1 2 3 3 3 0 Bromodomain associated Ish1 PF10281.9 PSC70841.1 - 0.15 12.3 0.2 0.46 10.8 0.0 1.9 2 1 0 2 2 2 0 Putative stress-responsive nuclear envelope protein PP2C PF00481.21 PSC70842.1 - 1e-57 195.8 0.2 1.5e-57 195.2 0.2 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 PSC70842.1 - 1.2e-06 28.2 0.4 0.0069 16.1 0.0 3.1 2 1 1 3 3 3 3 Leucine rich repeat LRRNT_2 PF08263.12 PSC70842.1 - 1.5e-06 28.4 2.0 4.5e-06 26.9 2.0 1.9 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain PP2C_2 PF13672.6 PSC70842.1 - 2e-06 27.6 0.7 6.5e-06 25.9 0.7 1.9 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.7 PSC70842.1 - 0.00034 21.0 0.1 0.49 10.9 0.0 3.4 2 1 1 3 3 3 1 Leucine Rich repeats (2 copies) SAC3_GANP PF03399.16 PSC70843.1 - 9.8e-16 58.0 0.1 4.9e-08 32.7 0.4 2.6 1 1 2 3 3 3 2 SAC3/GANP family Abi_C PF14355.6 PSC70843.1 - 0.012 15.7 0.0 4.1 7.6 0.1 2.7 2 0 0 2 2 2 0 Abortive infection C-terminus B3 PF02362.21 PSC70844.1 - 1.7e-06 27.8 0.0 3.1e-06 27.0 0.0 1.4 1 0 0 1 1 1 1 B3 DNA binding domain Pro_isomerase PF00160.21 PSC70845.1 - 1.4e-43 148.9 0.0 1.7e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DAGAT PF03982.13 PSC70847.1 - 1.7e-77 260.3 0.0 2.1e-77 259.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Oxidored_FMN PF00724.20 PSC70848.1 - 1.5e-85 287.5 0.0 1.8e-85 287.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Glyco_transf_92 PF01697.27 PSC70849.1 - 2e-19 70.3 0.0 3e-19 69.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PSC70849.1 - 6.6e-13 49.0 0.2 1.5e-12 47.8 0.2 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 MPC PF03650.13 PSC70850.1 - 4.7e-39 133.0 0.4 5.1e-39 132.8 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers Flavoprotein PF02441.19 PSC70851.1 - 4.6e-41 140.2 0.0 1.5e-40 138.5 0.0 1.8 2 0 0 2 2 2 1 Flavoprotein G8 PF10162.9 PSC70851.1 - 3.2e-16 59.5 0.0 5.5e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 G8 domain IBR PF01485.21 PSC70851.1 - 7.7e-15 54.9 16.5 3e-10 40.2 0.3 6.1 5 2 0 5 5 5 2 IBR domain, a half RING-finger domain Cmc1 PF08583.10 PSC70851.1 - 2.3e-11 43.5 2.1 2.3e-11 43.5 2.1 2.1 2 0 0 2 2 2 1 Cytochrome c oxidase biogenesis protein Cmc1 like zf-C3HC4_2 PF13923.6 PSC70851.1 - 0.0039 17.0 0.4 0.0039 17.0 0.4 5.5 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Ank PF00023.30 PSC70851.1 - 0.048 14.1 1.2 3.7 8.1 0.1 3.3 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 PSC70851.1 - 0.069 13.8 0.1 0.25 12.0 0.1 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) ShK PF01549.24 PSC70851.1 - 7.8 7.1 82.8 1.1 9.9 9.9 6.9 6 0 0 6 6 6 0 ShK domain-like PRORP PF16953.5 PSC70853.1 - 1.1e-46 159.4 0.0 1.8e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 Protein-only RNase P PPR_long PF17177.4 PSC70853.1 - 8.9e-40 136.3 0.1 5.7e-29 101.0 0.1 2.3 2 0 0 2 2 2 2 Pentacotripeptide-repeat region of PRORP RNase_Zc3h12a PF11977.8 PSC70853.1 - 7.2e-07 29.1 0.0 1.3e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain PPR_3 PF13812.6 PSC70853.1 - 0.0021 18.1 0.0 0.31 11.1 0.0 2.7 2 1 0 2 2 2 1 Pentatricopeptide repeat domain PPR PF01535.20 PSC70853.1 - 0.17 12.2 0.1 15 6.1 0.2 3.4 4 0 0 4 4 4 0 PPR repeat Radical_SAM PF04055.21 PSC70854.1 - 2.5e-15 57.3 0.0 4.2e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily LIAS_N PF16881.5 PSC70854.1 - 9.2e-08 32.5 0.0 1.6e-07 31.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Pkinase PF00069.25 PSC70855.1 - 5.1e-70 235.9 0.0 6.6e-70 235.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain ADK PF00406.22 PSC70855.1 - 8e-46 155.9 0.0 1.2e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 PSC70855.1 - 2.6e-35 121.8 0.0 4.2e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain Pkinase_Tyr PF07714.17 PSC70855.1 - 7.1e-28 97.6 0.0 3.3e-27 95.4 0.0 1.8 1 1 1 2 2 2 1 Protein tyrosine kinase AAA_18 PF13238.6 PSC70855.1 - 3.8e-08 33.9 0.0 7.4e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PSC70855.1 - 5e-06 26.7 0.0 1e-05 25.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 PSC70855.1 - 0.0017 18.0 0.2 0.11 12.2 0.1 2.2 2 0 0 2 2 2 1 Thymidylate kinase Kdo PF06293.14 PSC70855.1 - 0.0044 16.4 0.0 0.0071 15.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PSC70855.1 - 0.012 14.6 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 PSC70855.1 - 0.03 14.3 0.2 0.2 11.5 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.6 PSC70855.1 - 0.034 13.5 0.0 0.087 12.1 0.0 1.6 2 0 0 2 2 2 0 Kinase-like Zeta_toxin PF06414.12 PSC70855.1 - 0.054 12.8 0.0 0.16 11.2 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Ploopntkinase3 PF18751.1 PSC70855.1 - 0.07 13.0 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 PSC70855.1 - 0.071 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain F-box-like PF12937.7 PSC70856.1 - 2e-08 34.0 0.6 5.3e-08 32.6 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PSC70856.1 - 0.00025 20.9 0.1 0.00049 19.9 0.1 1.5 1 0 0 1 1 1 1 F-box domain PD40 PF07676.12 PSC70856.1 - 0.0013 18.6 0.1 0.81 9.7 0.0 3.0 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat CD36 PF01130.21 PSC70857.1 - 4.9e-32 111.1 0.0 3.6e-16 58.8 0.0 2.4 2 0 0 2 2 2 2 CD36 family Glycos_transf_1 PF00534.20 PSC70858.1 - 3.2e-20 72.4 0.0 5.2e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PSC70858.1 - 4.7e-19 69.2 0.0 2e-18 67.1 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 PSC70858.1 - 1.4e-08 35.0 0.1 5.9e-08 33.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycogen_syn PF05693.13 PSC70858.1 - 0.14 10.7 0.2 0.25 9.8 0.2 1.3 1 0 0 1 1 1 0 Glycogen synthase TFIIA PF03153.13 PSC70858.1 - 1.1 9.2 14.2 1.4 8.8 14.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ubiquitin PF00240.23 PSC70859.1 - 6.6e-07 29.0 0.0 8.6e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin family Glyoxalase PF00903.25 PSC70860.1 - 2.4e-07 31.0 0.1 8e-07 29.3 0.1 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 PSC70860.1 - 0.038 14.3 0.1 0.11 12.8 0.1 1.8 1 1 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 PSC70860.1 - 0.21 11.5 0.0 1.5 8.8 0.0 2.0 1 1 0 1 1 1 0 Glyoxalase-like domain YjeF_N PF03853.15 PSC70861.1 - 5.6e-35 120.8 0.0 8.7e-35 120.1 0.0 1.3 1 0 0 1 1 1 1 YjeF-related protein N-terminus Putative_PNPOx PF01243.20 PSC70861.1 - 5.3e-24 84.2 0.0 9.9e-24 83.4 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 PSC70861.1 - 3.4e-19 68.6 3.0 7.9e-19 67.5 3.0 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 PSC70861.1 - 9.3e-07 29.4 0.0 1.6e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Pyrid_ox_like PF16242.5 PSC70861.1 - 0.14 11.8 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase like SfsA PF03749.13 PSC70862.1 - 2.6e-28 98.6 0.0 1.9e-27 95.9 0.0 2.1 1 1 0 1 1 1 1 Sugar fermentation stimulation protein RE domain SfsA_N PF17746.1 PSC70862.1 - 2e-12 47.0 0.0 6e-12 45.6 0.0 1.9 2 0 0 2 2 2 1 SfsA N-terminal OB domain Abhydrolase_1 PF00561.20 PSC70862.1 - 9.2e-08 32.0 0.0 2.1e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC70862.1 - 0.00012 21.4 0.0 0.00025 20.4 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Pkinase_Tyr PF07714.17 PSC70863.1 - 2.4e-47 161.4 0.0 4.9e-47 160.4 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC70863.1 - 2.5e-41 141.8 0.0 3.4e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain CAAD PF14159.6 PSC70863.1 - 1e-19 70.2 0.0 2.1e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase LRR_8 PF13855.6 PSC70863.1 - 4.3e-09 36.0 3.4 1.9e-05 24.3 1.6 2.8 1 1 2 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 PSC70863.1 - 1.7e-07 31.4 3.0 0.03 14.7 2.3 3.5 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PSC70863.1 - 1.3e-05 25.1 3.5 3.9 8.4 0.0 5.1 5 0 0 5 5 5 1 Leucine Rich Repeat LRRNT_2 PF08263.12 PSC70863.1 - 0.00012 22.3 0.4 0.00012 22.3 0.4 2.3 2 0 0 2 2 2 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 PSC70863.1 - 0.12 12.4 0.3 1.1e+02 3.3 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich repeat APH PF01636.23 PSC70863.1 - 1.4 8.8 5.5 0.19 11.6 0.3 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pro_isomerase PF00160.21 PSC70864.1 - 0.00018 21.8 0.0 0.48 10.7 0.0 2.2 2 0 0 2 2 2 2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HNH_repeat PF18780.1 PSC70864.1 - 0.041 13.7 0.4 0.072 12.9 0.4 1.4 1 0 0 1 1 1 0 Homing endonuclease repeat CDK2AP PF09806.9 PSC70864.1 - 0.049 13.7 0.1 0.067 13.3 0.1 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein PAP_assoc PF03828.19 PSC70865.1 - 5.4e-12 45.7 0.0 1.9e-11 44.0 0.0 1.9 2 0 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 PSC70865.1 - 1.5e-08 34.8 0.0 3.3e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain NIF PF03031.18 PSC70865.1 - 0.00011 22.0 0.0 0.31 10.8 0.0 2.4 2 0 0 2 2 2 2 NLI interacting factor-like phosphatase Polbeta PF18765.1 PSC70865.1 - 0.041 14.0 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Acyl_transf_1 PF00698.21 PSC70866.1 - 3.6e-27 95.7 0.7 4.9e-27 95.3 0.7 1.1 1 0 0 1 1 1 1 Acyl transferase domain Ank PF00023.30 PSC70866.1 - 1.4e-08 34.8 0.1 0.00028 21.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank_2 PF12796.7 PSC70866.1 - 7.6e-08 32.8 0.0 1.8e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC70866.1 - 2e-07 31.2 0.0 5.3e-05 23.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC70866.1 - 2.4e-07 31.2 0.1 4.5e-06 27.1 0.1 2.4 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC70866.1 - 2.5e-05 24.3 0.2 0.21 12.2 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat rve PF00665.26 PSC70867.1 - 1.1e-28 99.8 0.0 5.2e-18 65.4 0.0 2.5 2 0 0 2 2 2 2 Integrase core domain Whib PF02467.16 PSC70867.1 - 0.00075 20.0 0.8 2.7 8.6 0.1 2.9 2 0 0 2 2 2 2 Transcription factor WhiB rve_3 PF13683.6 PSC70867.1 - 0.0097 15.7 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RTTN_N PF14726.6 PSC70867.1 - 0.18 12.6 0.2 12 6.8 0.0 2.8 2 0 0 2 2 2 0 Rotatin, an armadillo repeat protein, centriole functioning MCM PF00493.23 PSC70868.1 - 5.1e-92 307.0 0.0 8.8e-92 306.2 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PSC70868.1 - 1.7e-34 118.4 0.1 1.3e-32 112.3 0.0 2.5 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 PSC70868.1 - 3.8e-22 78.5 0.3 7.5e-22 77.6 0.3 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 PSC70868.1 - 1.5e-11 44.8 0.1 3.8e-11 43.5 0.0 1.8 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 PSC70868.1 - 1.8e-08 34.1 0.1 6.1e-06 25.8 0.0 2.3 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 PSC70868.1 - 0.00034 20.5 0.0 0.0008 19.3 0.0 1.6 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PSC70868.1 - 0.00037 20.5 0.0 0.0012 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 PSC70868.1 - 0.03 14.0 0.0 0.26 11.0 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 PSC70868.1 - 0.037 14.4 0.0 0.082 13.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Imm10 PF15588.6 PSC70868.1 - 0.33 11.1 2.3 4.5 7.4 0.3 2.5 2 0 0 2 2 2 0 Immunity protein 10 CBP_BcsO PF17037.5 PSC70869.1 - 0.22 11.7 5.5 0.26 11.4 5.5 1.2 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsO IPK PF03770.16 PSC70870.1 - 1e-41 143.0 0.0 1.3e-40 139.4 0.0 2.4 3 0 0 3 3 3 1 Inositol polyphosphate kinase Spt20 PF12090.8 PSC70870.1 - 0.22 11.1 11.8 0.39 10.3 11.8 1.3 1 0 0 1 1 1 0 Spt20 family DUF2828 PF11443.8 PSC70870.1 - 1.4 6.9 2.8 2 6.4 2.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) DRY_EERY PF09750.9 PSC70871.1 - 2e-19 70.2 0.0 2e-19 70.2 0.0 2.6 2 1 0 2 2 2 1 Alternative splicing regulator DRY_EERY PF09750.9 PSC70872.1 - 1.2e-19 70.9 0.0 1.2e-19 70.9 0.0 2.6 2 1 0 2 2 2 1 Alternative splicing regulator SET PF00856.28 PSC70873.1 - 2.8e-08 34.3 0.0 6.8e-08 33.1 0.0 1.7 1 1 0 1 1 1 1 SET domain ABC1 PF03109.16 PSC70875.1 - 2.8e-21 75.9 0.0 6.7e-13 48.9 0.1 2.3 2 0 0 2 2 2 2 ABC1 family DUF4224 PF13986.6 PSC70875.1 - 0.017 15.0 0.1 0.051 13.5 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4224) Pkinase PF00069.25 PSC70875.1 - 0.019 14.3 0.0 0.031 13.6 0.0 1.3 1 0 0 1 1 1 0 Protein kinase domain Spermine_synt_N PF17284.2 PSC70875.1 - 0.18 11.8 0.0 0.38 10.7 0.0 1.5 1 0 0 1 1 1 0 Spermidine synthase tetramerisation domain FBPase PF00316.20 PSC70876.1 - 6.9e-58 195.2 0.1 1e-57 194.7 0.1 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain C8 PF08742.11 PSC70876.1 - 0.029 14.8 0.8 0.071 13.5 0.4 1.8 2 0 0 2 2 2 0 C8 domain Nfu_N PF08712.11 PSC70877.1 - 3.1e-30 104.1 0.0 6.4e-30 103.1 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 PSC70877.1 - 1.2e-27 95.8 0.1 1.8e-27 95.3 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain YqfD PF06898.11 PSC70878.1 - 0.21 10.4 0.0 0.39 9.5 0.0 1.3 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD DTW PF03942.15 PSC70879.1 - 4.9e-14 52.5 0.0 7.2e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 DTW domain Pkinase PF00069.25 PSC70880.1 - 3.1e-61 207.1 0.0 3.6e-61 206.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC70880.1 - 3.1e-32 111.9 0.0 3.8e-32 111.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC70880.1 - 0.025 13.9 0.0 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 PSC70880.1 - 0.22 10.2 0.0 0.33 9.7 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase MARVEL PF01284.23 PSC70881.1 - 1.8e-17 63.7 21.5 2.1e-17 63.5 21.5 1.1 1 0 0 1 1 1 1 Membrane-associating domain WD40 PF00400.32 PSC70882.1 - 1.1e-22 79.9 4.8 3.2e-05 24.6 0.0 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC70882.1 - 7.9e-11 42.1 0.2 0.0028 17.9 0.0 4.5 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PSC70882.1 - 0.0011 18.0 0.6 0.27 10.1 0.0 2.5 2 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Gmad1 PF10647.9 PSC70882.1 - 0.0045 16.8 0.2 0.15 11.8 0.3 2.6 2 1 0 2 2 2 1 Lipoprotein LpqB beta-propeller domain Nup160 PF11715.8 PSC70882.1 - 0.02 13.5 2.1 0.031 12.9 0.1 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 S1 PF00575.23 PSC70883.1 - 4.2e-09 36.6 0.1 0.007 16.7 0.0 3.1 2 2 0 2 2 2 2 S1 RNA binding domain DUF2103 PF09876.9 PSC70883.1 - 2.9e-06 27.1 0.3 7.6e-06 25.8 0.3 1.7 1 0 0 1 1 1 1 Predicted metal-binding protein (DUF2103) OTU PF02338.19 PSC70884.1 - 1.3e-22 80.6 0.0 1e-21 77.7 0.0 2.2 1 1 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PSC70884.1 - 3.2e-05 23.5 0.0 0.0025 17.3 0.0 2.4 2 0 0 2 2 2 2 Peptidase C65 Otubain Peptidase_M48 PF01435.18 PSC70885.1 - 1.9 8.2 8.1 3.3 7.5 0.1 4.0 4 0 0 4 4 4 0 Peptidase family M48 TMA7 PF09072.10 PSC70886.1 - 5.7e-11 43.1 16.9 1.1e-10 42.1 16.9 1.5 1 0 0 1 1 1 1 Translation machinery associated TMA7 LRR_4 PF12799.7 PSC70886.1 - 1.5e-08 34.8 15.5 0.00041 20.7 1.6 6.1 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC70886.1 - 1.7e-08 34.1 18.8 0.1 12.3 0.0 6.3 6 1 0 6 6 6 4 Leucine rich repeat F-box-like PF12937.7 PSC70886.1 - 0.0029 17.5 0.9 0.0076 16.1 0.9 1.7 1 0 0 1 1 1 1 F-box-like FlaF PF07309.11 PSC70886.1 - 0.089 12.8 1.6 0.16 12.0 1.6 1.3 1 0 0 1 1 1 0 Flagellar protein FlaF CobT PF06213.12 PSC70886.1 - 0.14 11.5 6.8 0.24 10.8 6.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT LRR_1 PF00560.33 PSC70886.1 - 0.56 11.0 26.2 0.71 10.6 1.3 8.2 9 1 0 9 9 9 0 Leucine Rich Repeat mTERF PF02536.14 PSC70887.1 - 1.2e-17 63.8 0.0 1.6e-10 40.4 0.0 2.1 1 1 1 2 2 2 2 mTERF Sybindin PF04099.12 PSC70888.1 - 3.6e-21 75.6 0.1 3.9e-21 75.5 0.1 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 PSC70888.1 - 9.2e-07 29.1 0.0 1.1e-06 28.8 0.0 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region TPR_12 PF13424.6 PSC70889.1 - 0.0019 18.4 3.2 0.0037 17.5 3.2 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.6 PSC70889.1 - 0.0057 16.5 3.7 0.019 14.8 1.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 PSC70889.1 - 0.26 12.2 10.8 0.11 13.4 3.0 3.0 1 1 2 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 PSC70889.1 - 0.29 11.7 5.6 2.6 8.6 1.3 2.4 1 1 1 2 2 2 0 Tetratricopeptide repeat RPN7 PF10602.9 PSC70890.1 - 1.5e-51 174.6 0.0 2.4e-51 173.9 0.0 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 PSC70890.1 - 4.9e-12 46.3 0.0 1.2e-11 45.1 0.0 1.7 1 0 0 1 1 1 1 PCI domain HD PF01966.22 PSC70890.1 - 2.5e-07 30.9 0.1 9.2e-07 29.1 0.1 2.0 1 0 0 1 1 1 1 HD domain ubiquitin PF00240.23 PSC70890.1 - 0.00058 19.5 0.0 7.1 6.5 0.0 3.4 3 0 0 3 3 3 2 Ubiquitin family PRIMA1 PF16101.5 PSC70890.1 - 0.015 15.4 6.2 0.037 14.1 6.2 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 PDEase_I PF00233.19 PSC70890.1 - 0.17 11.6 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase TPR_12 PF13424.6 PSC70890.1 - 0.2 12.0 3.6 4.7 7.6 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Mito_fiss_reg PF05308.11 PSC70890.1 - 0.26 11.3 1.8 0.77 9.8 1.8 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF4461 PF14688.6 PSC70891.1 - 1.3e-27 97.4 0.0 1.6e-27 97.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4461) IMUP PF15761.5 PSC70891.1 - 0.47 11.2 18.7 1.5 9.5 9.8 2.4 2 0 0 2 2 2 0 Immortalisation up-regulated protein PPR_2 PF13041.6 PSC70892.1 - 1.4e-84 278.1 0.7 1.9e-09 37.6 0.0 16.4 7 5 11 18 18 18 14 PPR repeat family PPR PF01535.20 PSC70892.1 - 1.5e-54 178.5 16.2 6.9e-05 22.8 0.0 19.0 19 1 0 19 19 18 10 PPR repeat PPR_3 PF13812.6 PSC70892.1 - 3.6e-50 167.9 0.0 3.9e-07 30.1 0.0 11.2 8 3 3 12 12 12 10 Pentatricopeptide repeat domain PPR_long PF17177.4 PSC70892.1 - 4.6e-45 153.6 2.0 1.3e-13 50.8 0.0 6.0 3 1 3 6 6 6 6 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 PSC70892.1 - 3.6e-36 122.5 0.0 1.1e-05 25.0 0.0 15.9 17 0 0 17 17 17 8 PPR repeat Smr PF01713.21 PSC70892.1 - 1.2e-05 25.6 0.0 5.1e-05 23.6 0.0 2.2 1 0 0 1 1 1 1 Smr domain TPR_7 PF13176.6 PSC70892.1 - 0.0043 17.0 14.4 17 5.7 0.1 9.2 11 0 0 11 11 10 0 Tetratricopeptide repeat MRP-S27 PF10037.9 PSC70892.1 - 0.035 13.0 3.6 2 7.2 0.0 3.3 3 0 0 3 3 3 0 Mitochondrial 28S ribosomal protein S27 TPR_14 PF13428.6 PSC70892.1 - 0.51 11.3 59.5 18 6.5 0.0 16.4 11 6 8 19 19 16 0 Tetratricopeptide repeat TPR_2 PF07719.17 PSC70892.1 - 2.6 8.4 18.3 5.9 7.3 0.5 7.5 9 0 0 9 9 9 0 Tetratricopeptide repeat DUF4746 PF15928.5 PSC70892.1 - 9.9 5.5 7.3 1 8.7 2.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) PPR_2 PF13041.6 PSC70893.1 - 6.3e-85 279.2 0.4 1.9e-09 37.6 0.0 16.4 6 4 12 18 18 18 14 PPR repeat family PPR PF01535.20 PSC70893.1 - 9.8e-56 182.2 13.7 6.9e-05 22.8 0.0 18.7 19 1 0 19 19 18 10 PPR repeat PPR_3 PF13812.6 PSC70893.1 - 2.4e-50 168.5 0.0 4.6e-07 29.8 0.0 11.2 8 3 3 12 12 12 10 Pentatricopeptide repeat domain PPR_long PF17177.4 PSC70893.1 - 1.3e-44 152.1 2.4 1.4e-13 50.7 0.0 5.8 3 1 2 5 5 5 5 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 PSC70893.1 - 2.5e-36 123.0 0.0 1.1e-05 25.0 0.0 15.7 16 1 0 16 16 16 8 PPR repeat Smr PF01713.21 PSC70893.1 - 1.2e-05 25.6 0.0 5e-05 23.6 0.0 2.2 1 0 0 1 1 1 1 Smr domain TPR_7 PF13176.6 PSC70893.1 - 0.0038 17.2 14.4 17 5.7 0.1 9.3 11 0 0 11 11 10 0 Tetratricopeptide repeat MRP-S27 PF10037.9 PSC70893.1 - 0.032 13.1 3.6 2 7.2 0.0 3.4 3 0 0 3 3 3 0 Mitochondrial 28S ribosomal protein S27 TPR_14 PF13428.6 PSC70893.1 - 0.46 11.4 59.5 17 6.5 0.0 16.4 11 6 8 19 19 16 0 Tetratricopeptide repeat TPR_2 PF07719.17 PSC70893.1 - 2.4 8.5 18.3 5.9 7.3 0.5 7.6 9 0 0 9 9 9 0 Tetratricopeptide repeat DUF4746 PF15928.5 PSC70893.1 - 9.9 5.5 7.3 1 8.7 2.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Ras PF00071.22 PSC70894.1 - 1.1e-55 187.6 0.0 1.3e-55 187.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PSC70894.1 - 6.3e-33 113.6 0.0 9.4e-33 113.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PSC70894.1 - 1.2e-11 44.4 0.0 1.4e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PSC70894.1 - 4.8e-08 33.1 0.0 8.6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PSC70894.1 - 6.2e-06 25.7 0.0 7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PSC70894.1 - 3.9e-05 23.3 0.0 0.0013 18.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 PSC70894.1 - 0.00059 19.4 0.2 0.022 14.3 0.1 2.2 2 0 0 2 2 2 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 PSC70894.1 - 0.00096 19.1 0.1 0.0033 17.4 0.1 1.9 1 1 1 2 2 2 1 RsgA GTPase cobW PF02492.19 PSC70894.1 - 0.0012 18.4 0.0 0.002 17.8 0.0 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 PSC70894.1 - 0.0016 18.9 0.0 0.0027 18.1 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain NTPase_1 PF03266.15 PSC70894.1 - 0.0061 16.5 0.2 0.013 15.4 0.0 1.7 2 1 0 2 2 2 1 NTPase AAA_22 PF13401.6 PSC70894.1 - 0.01 16.1 0.0 0.026 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 PSC70894.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein Septin PF00735.18 PSC70894.1 - 0.013 14.7 0.1 0.023 14.0 0.1 1.4 1 0 0 1 1 1 0 Septin AAA_24 PF13479.6 PSC70894.1 - 0.017 14.8 0.0 0.032 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 PSC70894.1 - 0.019 14.4 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 PSC70894.1 - 0.021 14.6 0.1 0.11 12.2 0.1 2.0 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 PSC70894.1 - 0.041 13.8 0.1 0.073 13.0 0.0 1.4 2 0 0 2 2 1 0 ATPase domain predominantly from Archaea ATP_bind_1 PF03029.17 PSC70894.1 - 0.042 13.6 0.2 1.3 8.7 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NB-ARC PF00931.22 PSC70894.1 - 0.051 12.8 0.0 0.092 11.9 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain MCM PF00493.23 PSC70894.1 - 0.051 12.7 0.0 0.078 12.1 0.0 1.2 1 0 0 1 1 1 0 MCM P-loop domain AAA_5 PF07728.14 PSC70894.1 - 0.062 13.3 0.0 0.24 11.4 0.0 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DAP3 PF10236.9 PSC70894.1 - 0.071 12.3 0.1 0.098 11.8 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 NACHT PF05729.12 PSC70894.1 - 0.089 12.7 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 NACHT domain RuvB_N PF05496.12 PSC70894.1 - 0.094 12.5 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RNB PF00773.19 PSC70895.1 - 3e-100 335.7 0.0 4.2e-100 335.2 0.0 1.1 1 0 0 1 1 1 1 RNB domain GSHPx PF00255.19 PSC70895.1 - 2.9e-20 71.8 1.7 3e-18 65.4 0.7 2.8 2 1 0 2 2 2 1 Glutathione peroxidase OB_Dis3 PF17849.1 PSC70895.1 - 7.2e-20 70.8 0.0 1.3e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 PSC70895.1 - 3.5e-18 66.2 0.0 8.6e-18 64.9 0.0 1.7 1 0 0 1 1 1 1 PIN domain Rrp44_CSD1 PF17216.3 PSC70895.1 - 4.4e-11 42.7 0.0 8.1e-11 41.8 0.0 1.4 1 0 0 1 1 1 1 Rrp44-like cold shock domain Rrp44_S1 PF17215.3 PSC70895.1 - 1.5e-10 40.9 0.0 6.8e-10 38.8 0.0 2.0 1 1 0 1 1 1 1 S1 domain CSD2 PF17876.1 PSC70895.1 - 3.3e-05 24.0 0.5 0.026 14.7 0.0 3.3 4 0 0 4 4 4 2 Cold shock domain OB_RNB PF08206.11 PSC70895.1 - 0.0013 18.4 0.0 0.003 17.2 0.0 1.6 1 0 0 1 1 1 1 Ribonuclease B OB domain Ribosom_S12_S23 PF00164.25 PSC70896.1 - 2.8e-50 168.7 0.3 3.7e-50 168.3 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 IBN_N PF03810.19 PSC70898.1 - 5e-15 55.2 0.0 2.6e-14 52.9 0.0 2.3 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 PSC70898.1 - 0.0019 18.2 0.1 0.0076 16.3 0.1 2.1 1 0 0 1 1 1 1 Exportin 1-like protein Spidroin_N PF16763.5 PSC70898.1 - 0.18 11.8 0.0 0.48 10.4 0.0 1.7 1 0 0 1 1 1 0 Major ampullate spidroin 1, spider silk protein 1, N-term EII-GUT PF03608.13 PSC70899.1 - 0.18 11.7 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 PTS system enzyme II sorbitol-specific factor Mpv17_PMP22 PF04117.12 PSC70900.1 - 1.2e-20 73.5 0.3 2e-20 72.8 0.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family CBFD_NFYB_HMF PF00808.23 PSC70901.1 - 8.4e-08 32.4 5.5 1.9e-07 31.2 0.0 2.6 3 0 0 3 3 3 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PSC70901.1 - 9.3e-05 22.8 5.7 0.00027 21.3 0.0 2.1 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Baculo_PP31 PF05311.11 PSC70901.1 - 0.039 13.4 3.7 0.044 13.3 3.7 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Rtf2 PF04641.12 PSC70901.1 - 0.05 13.0 4.6 0.061 12.7 4.6 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Sec1 PF00995.23 PSC70901.1 - 0.11 11.7 0.8 0.13 11.5 0.8 1.1 1 0 0 1 1 1 0 Sec1 family Med3 PF11593.8 PSC70901.1 - 0.39 9.9 11.7 0.46 9.6 11.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal tRNA_lig_CPD PF08302.11 PSC70901.1 - 0.68 9.3 4.5 0.99 8.8 4.5 1.2 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain Coilin_N PF15862.5 PSC70901.1 - 0.75 9.6 6.8 1 9.2 6.8 1.2 1 0 0 1 1 1 0 Coilin N-terminus rve PF00665.26 PSC70902.1 - 8.4e-19 67.9 0.0 1.8e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC70902.1 - 0.0066 16.2 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain ATP-synt_F PF01990.17 PSC70903.1 - 4e-28 97.6 0.1 4.5e-28 97.4 0.1 1.0 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit MFS_1 PF07690.16 PSC70904.1 - 2e-07 30.3 38.0 6e-06 25.4 3.1 2.9 1 1 2 3 3 3 3 Major Facilitator Superfamily HpcH_HpaI PF03328.14 PSC70905.1 - 4.8e-29 101.1 0.0 1.2e-28 99.7 0.0 1.7 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family SBP PF03110.14 PSC70905.1 - 2.9e-20 72.4 2.8 2.9e-20 72.4 2.8 1.9 2 0 0 2 2 2 1 SBP domain Fes1 PF08609.10 PSC70905.1 - 0.37 11.7 7.5 1.2 10.0 0.1 2.9 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 GDPD PF03009.17 PSC70906.1 - 7.8e-11 42.2 0.0 1.1e-10 41.7 0.0 1.2 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family BCAS2 PF05700.11 PSC70907.1 - 5.8e-65 218.8 2.4 7.4e-65 218.5 2.4 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) DUF3584 PF12128.8 PSC70907.1 - 2.9e-05 21.9 0.0 4.4e-05 21.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF4407 PF14362.6 PSC70907.1 - 0.0082 15.5 4.3 0.011 15.1 4.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) MIS13 PF08202.11 PSC70907.1 - 0.058 12.7 0.1 0.087 12.1 0.1 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family SUIM_assoc PF16619.5 PSC70908.1 - 0.0077 16.3 0.1 0.039 14.0 0.1 2.2 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Disintegrin PF00200.23 PSC70909.1 - 0.0028 18.4 6.0 0.0028 18.4 6.0 3.9 4 1 0 4 4 4 2 Disintegrin SMP PF04927.12 PSC70909.1 - 0.01 16.3 2.2 0.01 16.3 2.2 4.4 4 0 0 4 4 4 0 Seed maturation protein MFS_1 PF07690.16 PSC70910.1 - 1.1e-15 57.4 39.0 1.6e-11 43.7 29.6 2.9 1 1 2 3 3 3 2 Major Facilitator Superfamily HRG PF16954.5 PSC70910.1 - 1.6 9.2 0.0 1.6 9.2 0.0 3.3 3 1 0 3 3 3 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene FSH1 PF03959.13 PSC70911.1 - 4e-35 121.4 0.0 5.9e-35 120.8 0.0 1.3 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Adaptin_binding PF10199.9 PSC70911.1 - 0.0099 16.5 0.0 0.011 16.3 0.0 1.3 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 TFIIA PF03153.13 PSC70911.1 - 0.012 15.6 3.0 0.014 15.4 3.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 PSC70911.1 - 0.013 14.4 0.3 0.015 14.3 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) THOC2_N PF16134.5 PSC70911.1 - 0.33 9.5 0.3 0.44 9.1 0.3 1.1 1 0 0 1 1 1 0 THO complex subunit 2 N-terminus Spt20 PF12090.8 PSC70911.1 - 5.4 6.6 12.9 7.6 6.1 12.9 1.1 1 0 0 1 1 1 0 Spt20 family TPR_2 PF07719.17 PSC70912.1 - 1.7e-09 37.1 24.2 0.026 14.6 1.1 6.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 PSC70912.1 - 2.3e-08 33.8 5.9 0.17 12.3 0.3 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 PSC70912.1 - 3.5e-07 29.8 19.8 0.22 11.4 0.2 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 PSC70912.1 - 5.7e-05 23.6 42.7 0.0011 19.5 2.6 6.7 4 2 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.6 PSC70912.1 - 9.7e-05 22.0 16.8 0.017 14.8 0.0 5.5 6 1 1 7 7 7 2 TPR repeat TPR_16 PF13432.6 PSC70912.1 - 0.00036 21.1 6.1 0.00036 21.1 6.1 6.9 6 2 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 PSC70912.1 - 0.00074 19.5 9.7 14 6.2 1.4 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat POTRA_TamA_1 PF17243.2 PSC70912.1 - 0.07 13.2 0.2 0.07 13.2 0.2 2.4 2 0 0 2 2 2 0 POTRA domain TamA domain 1 TPR_7 PF13176.6 PSC70912.1 - 6.5 7.0 8.9 2.1 8.5 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat PfkB PF00294.24 PSC70913.1 - 1.8e-30 106.3 20.5 1.2e-21 77.3 11.7 3.2 2 2 0 2 2 2 2 pfkB family carbohydrate kinase Ank_2 PF12796.7 PSC70914.1 - 6.8e-11 42.6 0.5 1.2e-10 41.9 0.3 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC70914.1 - 1.6e-09 37.8 1.3 7.9e-06 26.1 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC70914.1 - 3.5e-08 33.8 0.7 1.9e-07 31.5 0.4 2.1 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC70914.1 - 5e-08 32.6 0.5 0.022 15.3 0.1 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 PSC70914.1 - 6.1e-08 32.8 4.9 0.0034 17.8 0.3 2.6 2 0 0 2 2 2 2 Ankyrin repeat CRAL_TRIO PF00650.20 PSC70915.1 - 3.2e-26 91.9 0.0 4.5e-26 91.5 0.0 1.1 1 0 0 1 1 1 1 CRAL/TRIO domain Peptidase_C12 PF01088.21 PSC70916.1 - 4e-58 196.6 0.0 6.6e-58 195.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 LRR_8 PF13855.6 PSC70916.1 - 0.045 13.5 0.0 0.3 10.9 0.0 2.5 3 0 0 3 3 3 0 Leucine rich repeat zf-CCCH PF00642.24 PSC70916.1 - 0.34 10.9 1.9 23 5.0 0.1 2.5 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PSC70916.1 - 0.49 10.5 4.2 16 5.7 0.3 2.7 2 0 0 2 2 2 0 Zinc finger domain zf-CCCH_4 PF18044.1 PSC70916.1 - 0.61 10.0 3.0 21 5.0 0.2 2.5 2 0 0 2 2 2 0 CCCH-type zinc finger Ribosomal_L27 PF01016.19 PSC70917.1 - 0.25 11.4 0.0 26 5.0 0.0 2.1 2 0 0 2 2 2 0 Ribosomal L27 protein Metallothio_Euk PF12749.7 PSC70917.1 - 1.1 9.4 52.1 1.5 9.1 52.1 1.3 1 0 0 1 1 1 0 Eukaryotic metallothionein Metallothio_5 PF02067.15 PSC70917.1 - 3.5 7.8 62.9 4.9 7.3 27.5 3.1 1 1 1 2 2 2 0 Metallothionein family 5 LUC7 PF03194.15 PSC70918.1 - 1.6e-52 178.7 0.8 1.6e-52 178.7 0.8 1.8 2 0 0 2 2 2 1 LUC7 N_terminus Tropomyosin PF00261.20 PSC70919.1 - 7.4e-05 22.2 23.3 7.4e-05 22.2 23.3 7.4 2 2 5 7 7 7 5 Tropomyosin JIP_LZII PF16471.5 PSC70919.1 - 0.076 13.2 0.1 0.076 13.2 0.1 9.0 10 3 1 13 13 13 0 JNK-interacting protein leucine zipper II DUF4201 PF13870.6 PSC70920.1 - 1.6e-10 41.0 5.7 9.3e-10 38.5 1.5 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF4201) HALZ PF02183.18 PSC70920.1 - 1.2 9.5 3.6 12 6.2 0.7 3.2 3 0 0 3 3 3 0 Homeobox associated leucine zipper Lebercilin PF15619.6 PSC70920.1 - 4.2 7.0 12.9 0.94 9.1 8.7 2.0 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Pribosyltran_N PF13793.6 PSC70921.1 - 4.9e-47 158.7 0.0 1.2e-46 157.5 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 PSC70921.1 - 2.1e-24 86.6 0.4 7.3e-24 84.8 0.1 2.0 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 PSC70921.1 - 2.5e-17 62.8 0.5 4.8e-17 61.9 0.5 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 PSC70921.1 - 0.00047 19.7 0.1 0.0008 18.9 0.1 1.3 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 PSC70921.1 - 0.065 12.7 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase EF-hand_1 PF00036.32 PSC70922.1 - 6.4e-13 47.2 0.8 1.9e-05 23.9 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PSC70922.1 - 7e-11 41.2 0.6 0.00022 20.9 0.1 2.9 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 PSC70922.1 - 2.6e-10 40.6 0.1 6.4e-10 39.3 0.1 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 PSC70922.1 - 4.9e-10 38.5 0.6 5.8e-05 22.4 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PSC70922.1 - 7.5e-05 22.5 2.3 0.00047 20.0 0.3 2.4 2 1 1 3 3 3 2 EF-hand domain pair DUF4473 PF14747.6 PSC70922.1 - 0.13 12.8 0.0 2.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4473) MARVEL PF01284.23 PSC70923.1 - 3.8e-09 36.7 18.7 8.3e-09 35.6 18.7 1.6 1 0 0 1 1 1 1 Membrane-associating domain GTP_EFTU PF00009.27 PSC70924.1 - 8.5e-38 129.8 0.0 1.2e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 PSC70924.1 - 1.4e-24 86.5 0.0 2.8e-24 85.6 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 PSC70924.1 - 2.8e-07 30.8 0.2 7.1e-07 29.5 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PSC70924.1 - 0.00019 21.5 0.0 0.0049 16.9 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase eIF3_subunit PF08597.10 PSC70924.1 - 0.16 11.8 10.9 0.027 14.4 7.2 1.6 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit GTP_EFTU PF00009.27 PSC70925.1 - 9.2e-38 129.7 0.0 1.3e-37 129.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 PSC70925.1 - 1.5e-24 86.4 0.0 3e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 PSC70925.1 - 3e-07 30.7 0.2 7.4e-07 29.5 0.2 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PSC70925.1 - 0.0002 21.4 0.0 0.0052 16.9 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase eIF3_subunit PF08597.10 PSC70925.1 - 8.3 6.2 9.9 1.7 8.5 6.2 1.7 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit RRM_1 PF00076.22 PSC70926.1 - 1.2e-15 57.1 0.1 2e-15 56.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PSC70926.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif Spt20 PF12090.8 PSC70926.1 - 3.6 7.1 9.2 5.5 6.5 9.2 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 PSC70926.1 - 4 7.6 13.9 0.21 11.7 8.3 1.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Transket_pyr PF02779.24 PSC70927.1 - 5.5e-45 153.2 0.0 1.8e-44 151.5 0.0 1.9 2 0 0 2 2 2 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 PSC70927.1 - 1.5e-37 128.3 0.1 2.6e-37 127.5 0.1 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain PFOR_II PF17147.4 PSC70927.1 - 0.0018 18.5 0.1 0.005 17.1 0.0 1.8 1 1 1 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II DUF3558 PF12079.8 PSC70927.1 - 0.14 12.1 0.0 0.22 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) Hydrolase_4 PF12146.8 PSC70928.1 - 3.5e-60 203.2 0.0 4.1e-60 203.0 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PSC70928.1 - 1.2e-13 52.2 6.1 1.8e-13 51.6 6.1 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PSC70928.1 - 3.1e-09 36.9 0.1 2.3e-08 34.0 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 PSC70928.1 - 2.2e-05 24.7 0.5 4.3e-05 23.7 0.5 1.4 1 0 0 1 1 1 1 Thioesterase domain Peptidase_S9 PF00326.21 PSC70928.1 - 0.00014 21.4 0.0 0.0068 15.9 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family Esterase PF00756.20 PSC70928.1 - 0.014 15.1 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 0 Putative esterase Abhydrolase_5 PF12695.7 PSC70928.1 - 0.045 13.5 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family PGAP1 PF07819.13 PSC70928.1 - 0.11 12.2 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein NTF2 PF02136.20 PSC70930.1 - 1.3e-36 125.8 0.1 1.4e-36 125.7 0.1 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain eIF2A PF08662.11 PSC70931.1 - 4.1e-67 225.8 0.0 3.5e-66 222.8 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A WD40 PF00400.32 PSC70931.1 - 0.013 16.4 0.6 27 5.8 0.0 4.2 3 1 2 5 5 5 0 WD domain, G-beta repeat adh_short_C2 PF13561.6 PSC70932.1 - 4.6e-64 216.2 4.5 5.9e-64 215.8 4.5 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PSC70932.1 - 9e-58 195.0 6.0 1.1e-57 194.6 6.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PSC70932.1 - 2.2e-16 60.3 1.5 3.3e-16 59.7 1.5 1.3 1 0 0 1 1 1 1 KR domain TPR_1 PF00515.28 PSC70933.1 - 1.9e-16 59.1 23.1 1.2e-05 24.9 0.2 7.2 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_2 PF07719.17 PSC70933.1 - 5.7e-13 47.9 46.8 1.1e-05 25.1 1.1 9.3 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_16 PF13432.6 PSC70933.1 - 2e-09 38.0 23.7 2e-05 25.1 7.1 10.4 7 3 2 10 10 8 3 Tetratricopeptide repeat TPR_12 PF13424.6 PSC70933.1 - 2.4e-06 27.7 18.7 0.00017 21.8 3.7 8.1 6 3 4 10 10 9 4 Tetratricopeptide repeat TPR_11 PF13414.6 PSC70933.1 - 9.8e-06 25.2 17.2 6.1e-05 22.6 0.2 5.0 6 0 0 6 6 6 2 TPR repeat TPR_19 PF14559.6 PSC70933.1 - 4e-05 24.0 12.8 0.0015 19.0 5.4 6.4 6 1 1 7 7 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PSC70933.1 - 0.00018 21.6 19.7 0.00034 20.8 5.8 3.7 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 PSC70933.1 - 0.0034 17.5 1.9 0.0034 17.5 1.9 7.8 5 3 3 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 PSC70933.1 - 0.0073 16.4 19.1 12 6.4 0.1 7.6 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_3 PF07720.12 PSC70933.1 - 3.4 7.7 5.7 2.1 8.4 1.4 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 PSC70933.1 - 3.7 8.1 7.6 1.2e+02 3.4 0.4 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat MatE PF01554.18 PSC70934.1 - 1.5e-35 122.2 28.8 1.5e-22 80.0 11.8 2.4 2 0 0 2 2 2 2 MatE DUF789 PF05623.12 PSC70934.1 - 9.4e-31 107.6 0.0 9.1e-30 104.4 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF789) Polysacc_synt_C PF14667.6 PSC70934.1 - 5.6e-05 23.2 7.6 5.6e-05 23.2 7.6 2.9 3 0 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 PSC70935.1 - 1.5e-35 122.2 28.8 1.5e-22 80.0 11.8 2.4 2 0 0 2 2 2 2 MatE DUF789 PF05623.12 PSC70935.1 - 9.4e-31 107.6 0.0 8.9e-30 104.4 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF789) Polysacc_synt_C PF14667.6 PSC70935.1 - 5.6e-05 23.2 7.6 5.6e-05 23.2 7.6 2.9 3 0 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain Amino_oxidase PF01593.24 PSC70936.1 - 1.3e-95 321.3 3.0 3.7e-74 250.6 0.4 2.3 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PSC70936.1 - 5.2e-15 55.4 1.2 2.4e-14 53.3 1.2 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DEK_C PF08766.11 PSC70936.1 - 1.9e-09 37.3 1.0 4.4e-09 36.1 0.1 2.0 2 0 0 2 2 2 1 DEK C terminal domain Pyr_redox_2 PF07992.14 PSC70936.1 - 1.1e-08 34.7 1.1 9.3e-07 28.4 0.6 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PSC70936.1 - 2.1e-07 30.0 0.1 1.9e-06 26.9 0.2 2.2 2 0 0 2 2 2 1 HI0933-like protein DAO PF01266.24 PSC70936.1 - 2.2e-07 30.8 3.7 2.2e-07 30.8 3.7 3.9 4 0 0 4 4 4 1 FAD dependent oxidoreductase FAD_oxidored PF12831.7 PSC70936.1 - 5.9e-07 29.2 2.2 5.9e-07 29.2 2.2 3.5 4 0 0 4 4 3 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 PSC70936.1 - 7.3e-06 25.5 0.5 1.7e-05 24.2 0.5 1.6 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.27 PSC70936.1 - 2.4e-05 24.8 1.6 0.0003 21.3 0.4 3.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PSC70936.1 - 4.9e-05 22.7 0.1 9.2e-05 21.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 PSC70936.1 - 5.4e-05 22.6 3.4 9e-05 21.9 0.1 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PSC70936.1 - 8.4e-05 22.6 0.5 0.048 13.6 0.4 2.9 2 0 0 2 2 2 1 FAD-NAD(P)-binding AlaDh_PNT_C PF01262.21 PSC70936.1 - 0.00019 20.8 0.2 0.00019 20.8 0.2 2.6 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain SWIRM PF04433.17 PSC70936.1 - 0.00029 21.1 0.0 0.00083 19.7 0.0 1.8 1 0 0 1 1 1 1 SWIRM domain Lycopene_cycl PF05834.12 PSC70936.1 - 0.0017 17.5 7.1 0.0054 15.8 0.2 2.7 3 0 0 3 3 3 1 Lycopene cyclase protein GIDA PF01134.22 PSC70936.1 - 0.0019 17.4 0.9 0.0019 17.4 0.9 1.9 2 0 0 2 2 1 1 Glucose inhibited division protein A Glu_dehyd_C PF16912.5 PSC70936.1 - 0.006 16.1 0.0 0.013 15.0 0.0 1.5 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus Trp_halogenase PF04820.14 PSC70936.1 - 0.017 14.0 0.1 0.027 13.3 0.1 1.3 1 0 0 1 1 1 0 Tryptophan halogenase BH4 PF02180.17 PSC70936.1 - 0.025 14.4 0.0 4.3 7.2 0.0 2.5 2 0 0 2 2 2 0 Bcl-2 homology region 4 SRI PF08236.11 PSC70936.1 - 0.032 14.4 0.4 0.087 13.0 0.4 1.7 1 0 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain NAD_binding_7 PF13241.6 PSC70936.1 - 0.052 14.0 1.8 0.088 13.3 0.2 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding Thy1 PF02511.15 PSC70936.1 - 0.097 12.5 0.7 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 Thymidylate synthase complementing protein ApbA PF02558.16 PSC70936.1 - 0.17 11.6 0.4 0.51 10.0 0.2 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA VGLL4 PF15245.6 PSC70936.1 - 1.3 9.0 5.2 1.8 8.6 0.9 2.6 2 0 0 2 2 2 0 Transcription cofactor vestigial-like protein 4 PDDEXK_6 PF04720.12 PSC70936.1 - 4.2 7.3 6.9 25 4.7 4.0 2.8 2 0 0 2 2 2 0 PDDEXK-like family of unknown function Transcrip_reg PF01709.20 PSC70937.1 - 2.9e-69 233.1 0.1 3.4e-69 232.9 0.1 1.0 1 0 0 1 1 1 1 Transcriptional regulator CW_binding_2 PF04122.12 PSC70937.1 - 0.072 13.8 0.4 0.072 13.8 0.4 2.2 2 1 0 2 2 2 0 Putative cell wall binding repeat 2 SMP PF04927.12 PSC70939.1 - 0.029 14.8 2.5 0.029 14.8 2.5 3.1 4 0 0 4 4 4 0 Seed maturation protein DUF656 PF04920.12 PSC70939.1 - 0.095 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF656) HPTransfase PF10090.9 PSC70939.1 - 0.37 10.6 5.1 3.7 7.4 0.3 3.3 2 1 1 3 3 3 0 Histidine phosphotransferase C-terminal domain EF-hand_1 PF00036.32 PSC70940.1 - 4.7e-17 60.2 0.0 0.00014 21.1 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 PSC70940.1 - 5.5e-15 53.9 0.5 0.00044 20.0 0.1 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.6 PSC70940.1 - 4e-13 49.6 0.3 1.6e-06 28.5 0.0 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 PSC70940.1 - 5.4e-11 41.5 1.3 0.015 14.8 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 PSC70940.1 - 0.0025 17.6 3.8 1.1 9.2 0.1 3.3 1 1 2 3 3 3 2 EF-hand domain pair Asp-B-Hydro_N PF05279.11 PSC70940.1 - 0.0051 16.9 2.8 3.4 7.7 0.0 2.8 2 1 1 3 3 3 2 Aspartyl beta-hydroxylase N-terminal region AAA_assoc_2 PF16193.5 PSC70940.1 - 0.016 15.5 0.1 0.035 14.4 0.1 1.7 1 1 0 1 1 1 0 AAA C-terminal domain Dockerin_1 PF00404.18 PSC70940.1 - 0.026 14.7 1.9 0.55 10.5 0.5 2.6 1 1 2 3 3 3 0 Dockerin type I domain EF-hand_9 PF14658.6 PSC70940.1 - 0.072 13.4 0.0 18 5.7 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain Arf PF00025.21 PSC70941.1 - 9.4e-63 210.8 0.0 1.8e-62 209.9 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Vps39_2 PF10367.9 PSC70941.1 - 7.2e-18 65.0 0.3 9.5e-17 61.4 0.0 2.6 3 0 0 3 3 2 1 Vacuolar sorting protein 39 domain 2 Roc PF08477.13 PSC70941.1 - 6e-12 45.8 0.0 1.7e-11 44.3 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PSC70941.1 - 2.2e-10 40.3 0.0 6.3e-10 38.9 0.0 1.7 2 0 0 2 2 2 1 Ras family XRCC4 PF06632.12 PSC70941.1 - 8.7e-10 38.0 0.1 2e-09 36.8 0.1 1.5 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 G-alpha PF00503.20 PSC70941.1 - 1.2e-09 37.8 3.2 1.6e-08 34.1 0.0 2.5 2 1 1 3 3 3 1 G-protein alpha subunit SRPRB PF09439.10 PSC70941.1 - 8e-09 35.2 0.0 1.4e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 PSC70941.1 - 9.1e-09 35.0 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Clathrin PF00637.20 PSC70941.1 - 1.1e-08 35.1 0.0 4.5e-06 26.6 0.0 2.5 2 0 0 2 2 2 1 Region in Clathrin and VPS Vps39_1 PF10366.9 PSC70941.1 - 0.00024 21.3 0.0 0.013 15.8 0.0 2.7 3 0 0 3 3 2 1 Vacuolar sorting protein 39 domain 1 DUF2897 PF11446.8 PSC70941.1 - 0.032 14.1 0.1 0.032 14.1 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) MMR_HSR1 PF01926.23 PSC70941.1 - 0.042 13.9 0.0 0.1 12.7 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase Noggin PF05806.12 PSC70941.1 - 0.13 12.2 0.1 8.3 6.3 0.0 2.5 2 0 0 2 2 2 0 Noggin 6PF2K PF01591.18 PSC70941.1 - 0.16 11.3 0.1 0.28 10.5 0.1 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase zinc_ribbon_12 PF11331.8 PSC70941.1 - 0.18 11.7 0.2 0.46 10.3 0.2 1.7 1 0 0 1 1 1 0 Probable zinc-ribbon domain Spc7 PF08317.11 PSC70941.1 - 1.3 7.9 8.3 1.9 7.3 8.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DASH_Spc34 PF08657.10 PSC70941.1 - 8.5 6.1 6.2 13 5.5 6.2 1.2 1 0 0 1 1 1 0 DASH complex subunit Spc34 Suc_Fer-like PF06999.12 PSC70943.1 - 6.1e-27 94.8 0.0 9.1e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Sucrase/ferredoxin-like CRS1_YhbY PF01985.21 PSC70943.1 - 1e-11 44.8 0.1 1.8e-11 44.0 0.1 1.3 1 0 0 1 1 1 1 CRS1 / YhbY (CRM) domain Vac_ImportDeg PF09783.9 PSC70944.1 - 8.9e-38 129.6 0.0 1.3e-37 129.1 0.0 1.2 1 0 0 1 1 1 1 Vacuolar import and degradation protein R3H PF01424.22 PSC70944.1 - 4.2e-13 49.1 0.0 1.1e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 R3H domain zf-C3HC4_3 PF13920.6 PSC70944.1 - 0.00041 20.1 13.2 0.00041 20.1 13.2 3.9 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2 PF00096.26 PSC70944.1 - 0.00075 19.8 22.8 0.54 10.8 1.1 5.4 5 0 0 5 5 5 3 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 PSC70944.1 - 0.46 10.8 12.2 0.028 14.7 3.4 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 PSC70944.1 - 5.3 8.1 27.0 2.8 9.0 0.1 6.1 6 1 0 6 6 6 0 C2H2-type zinc finger PAN_4 PF14295.6 PSC70945.1 - 1.3e-07 31.4 5.1 3.4e-07 30.1 5.1 1.8 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 PSC70945.1 - 0.00079 19.3 1.5 0.0019 18.1 1.5 1.6 1 0 0 1 1 1 1 PAN domain Rhomboid PF01694.22 PSC70945.1 - 0.003 17.6 1.5 0.003 17.6 1.5 2.8 3 1 1 4 4 4 1 Rhomboid family Cpn10 PF00166.21 PSC70946.1 - 4.5e-52 174.1 6.1 8.4e-28 96.3 0.7 2.1 2 0 0 2 2 2 2 Chaperonin 10 Kd subunit LRR_8 PF13855.6 PSC70947.1 - 1.5e-32 111.1 22.5 1.8e-08 34.0 1.8 4.8 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 PSC70947.1 - 2.2e-32 110.5 0.3 1.8e-06 28.2 0.2 6.3 4 2 1 6 6 6 5 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PSC70947.1 - 6.1e-09 35.2 1.3 33 5.6 0.0 7.9 9 0 0 9 9 9 1 Leucine Rich Repeat LRR_6 PF13516.6 PSC70947.1 - 0.0053 16.7 4.9 69 3.9 0.1 6.5 8 0 0 8 8 8 0 Leucine Rich repeat Gar1 PF04410.14 PSC70948.1 - 9e-36 123.0 0.0 1.4e-35 122.3 0.0 1.2 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region FA_desaturase PF00487.24 PSC70948.1 - 3.3e-30 105.8 15.5 4.8e-30 105.2 15.5 1.2 1 0 0 1 1 1 1 Fatty acid desaturase Lipase_GDSL_2 PF13472.6 PSC70948.1 - 3.8e-19 69.8 0.0 8.2e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Cyt-b5 PF00173.28 PSC70948.1 - 4.1e-07 30.0 0.0 1e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Lipase_GDSL PF00657.22 PSC70948.1 - 0.00022 21.2 0.0 0.00043 20.3 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Methyltransf_16 PF10294.9 PSC70949.1 - 1.7e-10 40.9 0.0 5e-07 29.6 0.0 2.1 1 1 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 PSC70949.1 - 0.0061 16.4 0.0 0.0091 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 PSC70949.1 - 0.12 11.6 0.1 1.5 8.1 0.3 2.0 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G Voltage_CLC PF00654.20 PSC70951.1 - 4.6e-22 78.8 48.1 9e-21 74.5 47.1 2.1 2 0 0 2 2 2 2 Voltage gated chloride channel ELFV_dehydrog PF00208.21 PSC70952.1 - 1.9e-69 234.1 0.0 3.7e-69 233.1 0.0 1.4 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 PSC70952.1 - 7e-52 174.7 0.0 1.3e-51 173.8 0.0 1.5 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Trypsin PF00089.26 PSC70952.1 - 1.7e-35 122.8 0.1 2.9e-35 122.1 0.1 1.4 1 0 0 1 1 1 1 Trypsin TPP_enzyme_N PF02776.18 PSC70952.1 - 2.4e-31 108.7 1.1 7e-31 107.1 0.0 2.2 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 PSC70952.1 - 9.6e-17 61.0 0.0 2.3e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 PSC70952.1 - 1.5e-16 60.5 0.5 6.7e-16 58.4 0.1 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Furin-like_2 PF15913.5 PSC70952.1 - 0.0026 17.9 6.0 0.0026 17.9 6.0 4.9 2 1 2 4 4 4 3 Furin-like repeat, cysteine-rich Trypsin_2 PF13365.6 PSC70952.1 - 0.0045 17.9 0.0 0.019 15.9 0.0 2.1 1 0 0 1 1 1 1 Trypsin-like peptidase domain 2-Hacid_dh_C PF02826.19 PSC70952.1 - 0.0057 16.0 0.1 0.011 15.2 0.1 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AdoHcyase_NAD PF00670.21 PSC70952.1 - 0.077 13.1 0.0 0.23 11.5 0.0 1.8 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Myb_DNA-binding PF00249.31 PSC70953.1 - 2.1e-29 101.4 1.4 2.7e-14 53.1 0.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC70953.1 - 3e-22 78.6 0.2 1.4e-13 50.8 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain rve PF00665.26 PSC70953.1 - 4.3e-18 65.6 0.0 9.9e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain BK_channel_a PF03493.18 PSC70953.1 - 1.2e-15 57.5 0.0 2.6e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 PSC70953.1 - 2.6e-11 43.3 6.4 5.6e-11 42.2 6.4 1.5 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 PSC70953.1 - 8.6e-10 38.2 8.7 1.4e-09 37.5 8.7 1.3 1 0 0 1 1 1 1 Ion transport protein rve_3 PF13683.6 PSC70953.1 - 0.031 14.1 0.0 0.082 12.7 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain TrkA_C PF02080.21 PSC70953.1 - 0.064 13.1 0.0 0.52 10.2 0.0 2.4 2 0 0 2 2 2 0 TrkA-C domain Cwf_Cwc_15 PF04889.12 PSC70953.1 - 0.34 10.6 1.3 1.6 8.4 1.3 2.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PutA_N PF18083.1 PSC70953.1 - 0.46 10.5 2.3 1.5 8.8 2.3 1.9 1 0 0 1 1 1 0 Proline utilization A N-terminal domain AC_N PF16214.5 PSC70953.1 - 0.64 9.1 4.6 1.8 7.6 4.6 1.7 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region YL1 PF05764.13 PSC70953.1 - 4.2 7.4 13.7 2.5 8.1 2.5 3.2 3 0 0 3 3 3 0 YL1 nuclear protein Myb_DNA-binding PF00249.31 PSC70954.1 - 2.1e-29 101.4 1.4 2.7e-14 53.1 0.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC70954.1 - 3e-22 78.6 0.2 1.4e-13 50.8 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain rve PF00665.26 PSC70954.1 - 4.3e-18 65.6 0.0 9.9e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain BK_channel_a PF03493.18 PSC70954.1 - 1.2e-15 57.5 0.0 2.6e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 PSC70954.1 - 2.6e-11 43.3 6.4 5.6e-11 42.2 6.4 1.5 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 PSC70954.1 - 8.6e-10 38.3 8.7 1.4e-09 37.5 8.7 1.3 1 0 0 1 1 1 1 Ion transport protein rve_3 PF13683.6 PSC70954.1 - 0.031 14.1 0.0 0.082 12.7 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain TrkA_C PF02080.21 PSC70954.1 - 0.063 13.1 0.0 0.52 10.2 0.0 2.4 2 0 0 2 2 2 0 TrkA-C domain Cwf_Cwc_15 PF04889.12 PSC70954.1 - 0.34 10.6 1.3 1.6 8.4 1.3 2.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PutA_N PF18083.1 PSC70954.1 - 0.46 10.5 2.3 1.5 8.8 2.3 1.9 1 0 0 1 1 1 0 Proline utilization A N-terminal domain AC_N PF16214.5 PSC70954.1 - 0.64 9.1 4.6 1.8 7.6 4.6 1.7 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region YL1 PF05764.13 PSC70954.1 - 4.1 7.4 13.7 2.5 8.1 2.5 3.2 3 0 0 3 3 3 0 YL1 nuclear protein Myb_DNA-binding PF00249.31 PSC70955.1 - 2.1e-29 101.4 1.4 2.7e-14 53.1 0.1 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC70955.1 - 3e-22 78.6 0.2 1.4e-13 50.8 0.0 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain rve PF00665.26 PSC70955.1 - 4.3e-18 65.6 0.0 9.9e-18 64.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain BK_channel_a PF03493.18 PSC70955.1 - 1.2e-15 57.5 0.0 2.6e-15 56.4 0.0 1.6 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 PSC70955.1 - 2.6e-11 43.3 6.4 5.6e-11 42.2 6.4 1.5 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 PSC70955.1 - 8.6e-10 38.2 8.7 1.4e-09 37.5 8.7 1.3 1 0 0 1 1 1 1 Ion transport protein rve_3 PF13683.6 PSC70955.1 - 0.031 14.1 0.0 0.082 12.7 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain TrkA_C PF02080.21 PSC70955.1 - 0.064 13.1 0.0 0.52 10.2 0.0 2.4 2 0 0 2 2 2 0 TrkA-C domain Cwf_Cwc_15 PF04889.12 PSC70955.1 - 0.34 10.6 1.3 1.6 8.4 1.3 2.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein PutA_N PF18083.1 PSC70955.1 - 0.46 10.5 2.3 1.5 8.8 2.3 1.9 1 0 0 1 1 1 0 Proline utilization A N-terminal domain AC_N PF16214.5 PSC70955.1 - 0.64 9.1 4.6 1.8 7.6 4.6 1.7 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region YL1 PF05764.13 PSC70955.1 - 4.1 7.4 13.7 2.5 8.1 2.5 3.2 3 0 0 3 3 3 0 YL1 nuclear protein RRM_1 PF00076.22 PSC70956.1 - 4.3e-18 64.9 0.0 1.5e-08 34.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Acetyltransf_1 PF00583.25 PSC70956.1 - 9.4e-10 38.7 0.3 7.5e-09 35.8 0.3 2.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PSC70956.1 - 4.4e-09 36.6 0.0 9.1e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PSC70956.1 - 2.1e-05 24.5 0.1 0.00071 19.5 0.0 2.6 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC70956.1 - 0.00014 21.8 0.1 0.0014 18.6 0.1 2.3 1 1 0 1 1 1 1 FR47-like protein DUF4523 PF15023.6 PSC70956.1 - 0.00028 20.7 0.0 0.61 9.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4523) RRM_3 PF08777.11 PSC70956.1 - 0.0084 16.1 4.9 0.61 10.2 0.0 3.4 3 0 0 3 3 3 1 RNA binding motif RRM_occluded PF16842.5 PSC70956.1 - 0.086 12.7 0.0 13 5.8 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif Peptidase_M32 PF02074.15 PSC70957.1 - 2.2e-173 577.5 0.0 2.6e-173 577.3 0.0 1.0 1 0 0 1 1 1 1 Carboxypeptidase Taq (M32) metallopeptidase TetR_C_11 PF16859.5 PSC70957.1 - 0.42 10.9 7.6 2.7 8.3 2.7 2.7 2 1 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain PCIF1_WW PF12237.8 PSC70958.1 - 4.4e-53 179.4 0.0 7e-53 178.8 0.0 1.3 1 0 0 1 1 1 1 Phosphorylated CTD interacting factor 1 WW domain TPR_MLP1_2 PF07926.12 PSC70959.1 - 0.0095 16.0 19.7 0.0095 16.0 19.7 5.3 5 1 0 5 5 5 1 TPR/MLP1/MLP2-like protein GIT_CC PF16559.5 PSC70959.1 - 0.92 9.4 9.0 2 8.4 1.1 3.2 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor PsaN PF05479.11 PSC70960.1 - 0.32 11.2 2.6 9.7 6.4 2.6 2.1 1 1 0 1 1 1 0 Photosystem I reaction centre subunit N (PSAN or PSI-N) rve PF00665.26 PSC70961.1 - 1.9e-18 66.7 0.0 4.2e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain ubiquitin PF00240.23 PSC70961.1 - 0.0037 17.0 0.0 0.0074 16.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family rve_3 PF13683.6 PSC70961.1 - 0.015 15.0 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain rve PF00665.26 PSC70962.1 - 2e-18 66.7 0.0 4.3e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain ubiquitin PF00240.23 PSC70962.1 - 0.0037 17.0 0.0 0.0075 16.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family rve_3 PF13683.6 PSC70962.1 - 0.016 15.0 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Pex14_N PF04695.13 PSC70963.1 - 0.021 15.5 18.8 0.024 15.3 18.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 PSC70963.1 - 0.29 11.1 12.8 0.32 10.9 12.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Nop14 PF04147.12 PSC70963.1 - 0.62 8.2 20.7 0.7 8.0 20.7 1.0 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.11 PSC70963.1 - 0.7 9.2 23.5 0.82 9.0 23.5 1.0 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) FAM60A PF15396.6 PSC70963.1 - 0.94 9.4 7.2 1 9.3 7.2 1.2 1 0 0 1 1 1 0 Protein Family FAM60A TMEM214 PF10151.9 PSC70963.1 - 1.4 7.3 13.6 1.8 7.0 13.6 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator RR_TM4-6 PF06459.12 PSC70963.1 - 2.5 7.8 19.5 3 7.6 19.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF5349 PF17298.2 PSC70963.1 - 2.7 7.7 12.2 3.1 7.5 12.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Lin-8 PF03353.15 PSC70963.1 - 2.9 7.4 18.1 3.2 7.2 18.1 1.0 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Dsh_C PF12316.8 PSC70963.1 - 3 8.2 16.6 3.7 7.9 16.6 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal MMR1 PF08505.10 PSC70963.1 - 5.7 7.2 16.7 7.2 6.8 16.7 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Merozoite_SPAM PF07133.11 PSC70963.1 - 7.5 6.5 21.2 9.2 6.2 21.2 1.1 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) XAP5 PF04921.14 PSC70963.1 - 8 6.2 13.8 9.4 6.0 13.8 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator Neur_chan_memb PF02932.16 PSC70963.1 - 8.1 6.4 9.4 9.4 6.2 9.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FYRC PF05965.14 PSC70964.1 - 1.9e-08 34.3 0.1 7.5e-08 32.4 0.0 2.0 2 0 0 2 2 2 1 F/Y rich C-terminus PGA2 PF07543.12 PSC70964.1 - 0.6 10.1 16.5 0.072 13.1 2.5 2.3 2 0 0 2 2 2 0 Protein trafficking PGA2 RAM PF15320.6 PSC70964.1 - 0.84 10.3 21.7 0.58 10.8 11.0 2.4 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein FoP_duplication PF13865.6 PSC70964.1 - 1.6 9.3 21.4 0.66 10.6 9.8 2.3 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Spt20 PF12090.8 PSC70964.1 - 2.8 7.5 33.8 0.35 10.5 4.5 2.1 2 0 0 2 2 2 0 Spt20 family Prothymosin PF03247.14 PSC70964.1 - 8.5 6.9 20.7 1.6 9.3 6.7 2.2 2 0 0 2 2 2 0 Prothymosin/parathymosin family Prefoldin PF02996.17 PSC70966.1 - 1.5e-10 41.0 0.0 2e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Prefoldin subunit DUF2301 PF10063.9 PSC70967.1 - 9.6e-45 152.3 0.1 1.7e-44 151.5 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized integral membrane protein (DUF2301) SET PF00856.28 PSC70967.1 - 2.7e-11 44.1 0.0 6.2e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 SET domain AF-4 PF05110.13 PSC70967.1 - 0.41 8.7 2.4 0.56 8.2 2.4 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein HECT PF00632.25 PSC70968.1 - 7.6e-79 265.4 0.0 1e-78 265.0 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) adh_short PF00106.25 PSC70969.1 - 8.7e-43 146.1 1.9 4.4e-26 91.5 0.4 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PSC70969.1 - 6.3e-36 124.1 4.6 5.1e-20 72.0 0.7 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC70969.1 - 0.00026 20.9 1.6 0.00031 20.7 0.3 1.7 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 PSC70969.1 - 0.0011 18.5 0.0 0.005 16.3 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.18 PSC70969.1 - 0.0029 17.5 0.4 0.0047 16.8 0.4 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 PSC70969.1 - 0.084 13.6 0.1 0.17 12.6 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain AdoHcyase_NAD PF00670.21 PSC70969.1 - 0.18 11.9 6.2 0.059 13.4 2.2 2.1 3 0 0 3 3 3 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain UDPGP PF01704.18 PSC70970.1 - 2e-17 63.0 0.0 2.9e-17 62.4 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase adh_short PF00106.25 PSC70971.1 - 1e-40 139.3 0.0 1.7e-40 138.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC70971.1 - 2.2e-27 96.1 0.9 4e-27 95.3 0.9 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase MARVEL PF01284.23 PSC70971.1 - 2.3e-12 47.2 17.0 2.3e-12 47.2 17.0 2.1 2 0 0 2 2 2 1 Membrane-associating domain KR PF08659.10 PSC70971.1 - 1.8e-11 44.3 3.0 1.8e-11 44.3 3.0 1.8 2 0 0 2 2 2 1 KR domain Peptidase_S10 PF00450.22 PSC70972.1 - 2.6e-126 422.4 0.0 2.9e-126 422.3 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase PALP PF00291.25 PSC70973.1 - 1.9e-52 178.5 0.0 2.6e-52 178.1 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Peptidase_C1 PF00112.23 PSC70974.1 - 1.7e-39 136.2 0.0 5.3e-39 134.6 0.0 1.7 1 1 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PSC70974.1 - 0.00015 22.2 0.8 0.0004 20.8 0.8 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PSC70974.1 - 0.12 11.1 0.2 12 4.5 0.0 2.4 2 0 0 2 2 2 0 Peptidase C1-like family Peptidase_C1 PF00112.23 PSC70975.1 - 1.5e-39 136.4 0.0 5.1e-39 134.6 0.0 1.7 1 1 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PSC70975.1 - 0.00014 22.2 0.8 0.00038 20.8 0.8 1.7 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PSC70975.1 - 0.15 10.8 0.6 12 4.6 0.0 2.4 3 0 0 3 3 3 0 Peptidase C1-like family DUF812 PF05667.11 PSC70976.1 - 0.033 13.1 2.1 0.042 12.7 2.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DivIC PF04977.15 PSC70976.1 - 0.061 13.1 8.0 0.22 11.3 6.0 2.1 2 0 0 2 2 2 0 Septum formation initiator RmuC PF02646.16 PSC70976.1 - 0.068 12.3 1.5 0.1 11.7 1.5 1.2 1 0 0 1 1 1 0 RmuC family ACP_syn_III_C PF08541.10 PSC70976.1 - 0.16 12.1 1.6 2 8.6 0.1 2.6 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Macoilin PF09726.9 PSC70976.1 - 1.3 7.5 6.6 3 6.3 6.6 1.5 1 1 0 1 1 1 0 Macoilin family DUF4140 PF13600.6 PSC70976.1 - 3.4 8.2 7.6 0.63 10.5 2.3 2.4 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) HemX PF04375.14 PSC70976.1 - 6.2 6.0 11.3 9.2 5.4 5.6 2.2 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase AAA_12 PF13087.6 PSC70977.1 - 4e-62 209.4 0.0 5.7e-62 208.9 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PSC70977.1 - 3.9e-61 207.1 0.0 2.1e-30 106.4 0.1 2.6 1 1 1 2 2 2 2 AAA domain AAA_30 PF13604.6 PSC70977.1 - 3e-11 43.4 0.8 0.00028 20.6 0.1 2.8 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 PSC70977.1 - 3.8e-08 33.8 0.3 0.0074 16.6 0.2 2.5 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 PSC70977.1 - 2.2e-05 24.3 0.1 0.038 13.7 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 PSC70977.1 - 0.0081 16.6 0.1 0.054 13.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain DUF2075 PF09848.9 PSC70977.1 - 0.042 13.1 3.6 1.4 8.1 0.1 2.5 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) Helicase_RecD PF05127.14 PSC70977.1 - 0.055 13.3 0.1 1.1 9.1 0.0 3.0 3 1 0 3 3 3 0 Helicase UvrD-helicase PF00580.21 PSC70977.1 - 0.098 12.2 0.0 14 5.0 0.0 2.3 2 0 0 2 2 2 0 UvrD/REP helicase N-terminal domain UvrD_C_2 PF13538.6 PSC70977.1 - 0.11 12.3 0.0 0.36 10.7 0.0 2.0 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain Ribosomal_S15 PF00312.22 PSC70979.1 - 1.3e-28 99.0 0.6 2.1e-28 98.3 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 WD40 PF00400.32 PSC70979.1 - 1.1e-08 35.6 0.5 0.024 15.5 0.3 5.8 6 0 0 6 6 6 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC70979.1 - 0.0052 17.1 0.0 5.2 7.5 0.0 4.3 4 1 1 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 PSC70979.1 - 0.016 15.6 1.3 18 6.0 1.2 4.2 3 1 0 3 3 3 0 PQQ-like domain Ribosomal_S15 PF00312.22 PSC70981.1 - 2e-28 98.4 0.6 3.1e-28 97.8 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S15 WD40 PF00400.32 PSC70981.1 - 5.3e-08 33.4 0.5 0.033 15.1 0.3 5.8 6 0 0 6 6 6 1 WD domain, G-beta repeat PQQ_3 PF13570.6 PSC70981.1 - 0.054 14.0 1.5 24 5.6 1.1 4.1 3 1 0 3 3 3 0 PQQ-like domain TPR_1 PF00515.28 PSC70982.1 - 4.5e-13 48.4 5.8 0.0001 21.9 0.1 5.0 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 PSC70982.1 - 5.7e-11 41.7 11.2 0.056 13.6 0.1 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_12 PF13424.6 PSC70982.1 - 3.1e-07 30.6 23.0 0.0039 17.4 0.2 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_7 PF13176.6 PSC70982.1 - 1.9e-05 24.4 6.9 0.004 17.1 0.1 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 PSC70982.1 - 5.6e-05 22.9 21.2 0.51 10.3 0.2 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 PSC70982.1 - 0.0013 18.8 7.4 0.4 11.0 0.1 3.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TFIIA PF03153.13 PSC70982.1 - 3.2 7.7 14.7 6.6 6.6 14.7 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 PSC70982.1 - 6.1 6.4 12.1 16 5.0 12.1 1.7 1 0 0 1 1 1 0 Spt20 family EMG1 PF03587.14 PSC70983.1 - 1.3e-73 246.9 0.0 1.5e-73 246.7 0.0 1.0 1 0 0 1 1 1 1 EMG1/NEP1 methyltransferase Ephrin_rec_like PF07699.13 PSC70984.1 - 2.5e-35 120.0 56.1 1.4e-07 31.2 3.8 7.2 2 2 5 7 7 7 7 Putative ephrin-receptor like TNFR_c6 PF00020.18 PSC70984.1 - 0.00057 20.2 49.9 0.077 13.4 0.3 9.2 3 3 8 11 11 11 7 TNFR/NGFR cysteine-rich region VSP PF03302.13 PSC70984.1 - 0.023 13.6 35.2 0.017 14.0 4.7 3.7 1 1 2 3 3 3 0 Giardia variant-specific surface protein Nup214_FG PF18617.1 PSC70984.1 - 2.8 8.5 6.5 5.8 7.5 0.1 3.1 3 0 0 3 3 3 0 Nucleoporin Nup214 phenylalanine-glycine (FG) domain DUF2318 PF10080.9 PSC70984.1 - 5.9 7.1 29.9 0.21 11.7 1.3 5.3 2 2 4 6 6 6 0 Predicted membrane protein (DUF2318) SARS_X4 PF08779.10 PSC70984.1 - 7.7 6.8 8.9 12 6.2 2.0 3.9 3 1 0 3 3 3 0 SARS coronavirus X4 like adh_short PF00106.25 PSC70985.1 - 2.3e-44 151.2 0.0 2.8e-44 150.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC70985.1 - 8.2e-24 84.4 0.0 1e-23 84.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC70985.1 - 1.4e-13 51.2 0.0 2.4e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 KR domain Glyco_trans_4_4 PF13579.6 PSC70985.1 - 0.00017 22.1 1.8 0.00023 21.7 0.2 1.9 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain Pyr_redox PF00070.27 PSC70985.1 - 0.0045 17.5 0.0 0.0081 16.7 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase RmlD_sub_bind PF04321.17 PSC70985.1 - 0.035 13.2 0.0 0.057 12.5 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Glyco_transf_4 PF13439.6 PSC70985.1 - 0.049 13.6 0.0 0.18 11.8 0.0 1.9 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Epimerase PF01370.21 PSC70985.1 - 0.1 12.0 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF1206 PF06724.11 PSC70985.1 - 0.16 12.1 3.6 0.23 11.6 0.7 2.7 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1206) Med14 PF08638.11 PSC70986.1 - 5.4e-33 114.0 0.1 9e-33 113.3 0.1 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 GrpB PF04229.14 PSC70986.1 - 0.049 13.8 0.3 0.091 13.0 0.3 1.4 1 0 0 1 1 1 0 GrpB protein Med14 PF08638.11 PSC70987.1 - 5.4e-33 114.0 0.1 8.9e-33 113.3 0.1 1.3 1 0 0 1 1 1 1 Mediator complex subunit MED14 GrpB PF04229.14 PSC70987.1 - 0.049 13.8 0.3 0.09 13.0 0.3 1.4 1 0 0 1 1 1 0 GrpB protein Neurochondrin PF05536.11 PSC70988.1 - 3.1e-41 141.5 0.0 3.9e-29 101.5 0.0 3.6 2 1 0 2 2 2 2 Neurochondrin Oxidored_FMN PF00724.20 PSC70989.1 - 6.9e-71 239.3 0.0 1.7e-51 175.5 0.0 3.1 2 1 1 3 3 3 3 NADH:flavin oxidoreductase / NADH oxidase family Ribosomal_60s PF00428.19 PSC70989.1 - 2.3 8.9 14.7 7.3 7.3 14.7 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein Tic110 PF16940.5 PSC70989.1 - 5.9 5.3 7.3 8.2 4.8 7.3 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter GHMP_kinases_C PF08544.13 PSC70990.1 - 8.7e-11 42.0 3.8 8.7e-11 42.0 0.2 2.5 2 0 0 2 2 2 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 PSC70990.1 - 5.3e-09 36.2 4.6 5.3e-09 36.2 4.6 2.4 2 0 0 2 2 2 1 GHMP kinases N terminal domain DUF5061 PF16587.5 PSC70990.1 - 0.0053 16.8 0.1 0.0053 16.8 0.1 1.8 2 0 0 2 2 2 1 17 kDa common-antigen outer membrane protein CsrA PF02599.16 PSC70990.1 - 0.045 13.7 0.0 17 5.4 0.0 2.5 2 0 0 2 2 2 0 Global regulator protein family Hol_Tox PF16935.5 PSC70990.1 - 0.06 13.4 0.2 19 5.4 0.0 2.6 2 0 0 2 2 2 0 Putative Holin-like Toxin (Hol-Tox) DUF3042 PF11240.8 PSC70990.1 - 0.37 10.8 10.2 4.4 7.4 0.3 3.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) DIM PF08194.12 PSC70990.1 - 0.58 10.4 9.2 28 5.0 0.3 4.5 4 0 0 4 4 4 0 DIM protein zf-DNL PF05180.12 PSC70991.1 - 4.8e-27 93.7 0.0 6.6e-27 93.2 0.0 1.2 1 0 0 1 1 1 1 DNL zinc finger zinc_ribbon_4 PF13717.6 PSC70991.1 - 0.0018 18.1 0.4 1.8 8.5 0.0 2.4 2 0 0 2 2 2 2 zinc-ribbon domain CDK2AP PF09806.9 PSC70991.1 - 0.21 11.6 2.9 0.31 11.1 2.9 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein TFIIS_C PF01096.18 PSC70991.1 - 3.2 7.7 6.3 9.7 6.1 1.5 2.2 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS) Ephrin_rec_like PF07699.13 PSC70993.1 - 4.5e-35 119.2 57.2 1.7e-07 30.9 3.9 7.2 2 2 5 7 7 7 7 Putative ephrin-receptor like TNFR_c6 PF00020.18 PSC70993.1 - 0.00025 21.4 48.5 0.067 13.6 0.2 9.2 3 3 8 11 11 11 7 TNFR/NGFR cysteine-rich region VSP PF03302.13 PSC70993.1 - 0.03 13.2 34.8 0.35 9.7 14.9 3.6 2 2 0 2 2 2 0 Giardia variant-specific surface protein Nup214_FG PF18617.1 PSC70993.1 - 4.4 7.9 6.7 5.8 7.5 0.1 3.0 3 0 0 3 3 3 0 Nucleoporin Nup214 phenylalanine-glycine (FG) domain SARS_X4 PF08779.10 PSC70993.1 - 7.9 6.8 8.9 12 6.2 2.0 3.9 3 1 0 3 3 3 0 SARS coronavirus X4 like DUF2318 PF10080.9 PSC70993.1 - 9.8 6.4 30.4 0.19 11.8 1.1 5.3 2 2 4 6 6 6 0 Predicted membrane protein (DUF2318) SANT_DAMP1_like PF16282.5 PSC70994.1 - 5.9e-08 32.8 1.3 0.0015 18.7 0.2 2.5 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 DUF3138 PF11336.8 PSC70994.1 - 3.1 6.3 6.4 4.7 5.7 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) LBR_tudor PF09465.10 PSC70995.1 - 0.038 13.8 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Lamin-B receptor of TUDOR domain ADH_N PF08240.12 PSC70995.1 - 0.1 12.5 0.5 6.3 6.7 0.0 2.5 2 0 0 2 2 2 0 Alcohol dehydrogenase GroES-like domain AUX_IAA PF02309.16 PSC70995.1 - 3.3 7.5 5.4 0.91 9.3 2.0 1.7 2 0 0 2 2 2 0 AUX/IAA family zf-CXXC PF02008.20 PSC70995.1 - 5.2 7.2 12.0 7 6.8 1.9 2.6 2 0 0 2 2 2 0 CXXC zinc finger domain Protamine_like PF06382.11 PSC70995.1 - 6.4 7.0 6.3 6.1 7.0 0.4 2.5 2 0 0 2 2 2 0 Protamine and protamine like Pkinase_Tyr PF07714.17 PSC70996.1 - 7.1e-32 110.7 0.0 1.4e-20 73.7 0.0 3.0 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PSC70996.1 - 6.4e-29 101.1 0.0 8.1e-25 87.7 0.0 3.7 2 1 0 2 2 2 1 Protein kinase domain Nitrate_red_gam PF02665.14 PSC70996.1 - 0.019 14.5 0.2 0.03 13.9 0.2 1.2 1 0 0 1 1 1 0 Nitrate reductase gamma subunit Kdo PF06293.14 PSC70996.1 - 0.079 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gram_pos_anchor PF00746.21 PSC70996.1 - 6.8 6.7 8.0 31 4.6 8.0 2.2 1 1 0 1 1 1 0 LPXTG cell wall anchor motif BRCT PF00533.26 PSC70998.1 - 6.9e-10 39.2 0.0 1.8e-05 25.0 0.0 2.7 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain zf-C3HC4_2 PF13923.6 PSC70998.1 - 1.4e-06 28.0 20.2 1.4e-06 28.0 20.2 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC70998.1 - 2.2e-06 27.9 18.4 2.2e-06 27.9 18.4 2.7 3 0 0 3 3 3 1 Ring finger domain RcbX PF02341.15 PSC70998.1 - 4.4e-06 26.9 0.0 8.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 RbcX protein PTCB-BRCT PF12738.7 PSC70998.1 - 7.8e-06 25.7 7.1 0.00036 20.4 0.0 2.8 3 0 0 3 3 2 2 twin BRCT domain zf-C3HC4 PF00097.25 PSC70998.1 - 2.8e-05 23.9 20.2 2.8e-05 23.9 20.2 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Pkinase PF00069.25 PSC70998.1 - 3e-05 23.5 0.0 5.1e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain zf-RING_6 PF14835.6 PSC70998.1 - 3.4e-05 23.6 5.9 7.2e-05 22.6 5.9 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein BRCT_2 PF16589.5 PSC70998.1 - 4e-05 23.9 0.0 0.14 12.6 0.0 2.5 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain zf-C3HC4_3 PF13920.6 PSC70998.1 - 9.6e-05 22.2 17.0 9.6e-05 22.2 17.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC70998.1 - 0.00012 22.1 15.8 0.00054 19.9 15.9 2.1 1 1 0 1 1 1 1 RING-type zinc-finger Pkinase_Tyr PF07714.17 PSC70998.1 - 0.0012 18.2 0.0 0.002 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-RING_5 PF14634.6 PSC70998.1 - 0.0019 18.1 17.7 0.0019 18.1 17.7 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PSC70998.1 - 0.056 13.6 19.5 0.14 12.3 19.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING U-box PF04564.15 PSC70998.1 - 0.072 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 U-box domain zf-rbx1 PF12678.7 PSC70998.1 - 0.12 12.6 11.9 0.5 10.7 11.9 2.1 1 0 0 1 1 1 0 RING-H2 zinc finger domain RTT107_BRCT_5 PF16770.5 PSC70998.1 - 0.15 12.0 0.0 0.37 10.7 0.0 1.7 2 0 0 2 2 1 0 Regulator of Ty1 transposition protein 107 BRCT domain zf-Nse PF11789.8 PSC70998.1 - 0.15 11.9 13.9 0.3 11.0 13.9 1.4 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 PSC70998.1 - 0.35 10.7 12.1 0.25 11.1 8.2 2.6 2 0 0 2 2 2 0 RING-like zinc finger CTU2 PF10288.9 PSC70998.1 - 9.6 6.5 8.2 3.1 8.1 1.3 2.7 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 DAGAT PF03982.13 PSC71000.1 - 5.8e-61 206.0 0.0 6.8e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Bromodomain PF00439.25 PSC71001.1 - 2.3e-17 62.8 0.2 4.8e-17 61.8 0.1 1.6 2 0 0 2 2 2 1 Bromodomain Transferase PF02458.15 PSC71001.1 - 2e-10 39.9 0.0 0.00011 21.1 0.0 3.4 2 2 0 2 2 2 2 Transferase family Acetyltransf_1 PF00583.25 PSC71001.1 - 3.8e-08 33.6 0.0 8.6e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PSC71001.1 - 2.1e-06 27.7 0.0 3.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PSC71001.1 - 0.0095 16.4 0.1 0.022 15.2 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NADH_Oxid_Nqo15 PF11497.8 PSC71001.1 - 0.011 15.7 0.1 4.5 7.3 0.0 3.0 4 0 0 4 4 4 0 NADH-quinone oxidoreductase chain 15 Aldo_ket_red PF00248.21 PSC71002.1 - 9.2e-48 162.9 0.0 6.2e-45 153.6 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family PAN_4 PF14295.6 PSC71003.1 - 5e-08 32.7 0.7 5e-08 32.7 0.7 4.0 4 0 0 4 4 4 1 PAN domain Sec1 PF00995.23 PSC71004.1 - 5.4e-96 323.1 0.0 6.3e-96 322.9 0.0 1.0 1 0 0 1 1 1 1 Sec1 family DegS PF05384.11 PSC71004.1 - 0.099 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Sensor protein DegS Semialdhyde_dh PF01118.24 PSC71005.1 - 2.6e-30 105.3 0.0 4.8e-30 104.5 0.0 1.5 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Semialdhyde_dhC PF02774.18 PSC71005.1 - 1.2e-15 58.1 0.0 2.6e-15 57.0 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, dimerisation domain SPRY PF00622.28 PSC71005.1 - 8.4e-11 42.0 0.2 5e-08 33.1 0.0 2.5 2 0 0 2 2 2 2 SPRY domain NAD_binding_10 PF13460.6 PSC71005.1 - 0.0024 17.8 0.0 0.0045 16.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding TFIIA PF03153.13 PSC71005.1 - 0.0027 17.8 4.9 0.037 14.0 2.8 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit NmrA PF05368.13 PSC71005.1 - 0.0052 16.4 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family DapB_N PF01113.20 PSC71005.1 - 0.01 15.9 0.0 0.025 14.7 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus GFO_IDH_MocA PF01408.22 PSC71005.1 - 0.033 15.0 0.0 0.077 13.8 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Vps53_N PF04100.12 PSC71006.1 - 2.1e-101 339.6 0.1 3.1e-101 339.1 0.1 1.2 1 0 0 1 1 1 1 Vps53-like, N-terminal Vps54_N PF10475.9 PSC71006.1 - 3.3e-09 36.5 1.3 1.5e-08 34.3 0.8 1.9 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex Spc7 PF08317.11 PSC71006.1 - 0.003 16.5 0.9 0.0068 15.3 0.4 1.7 1 1 0 1 1 1 1 Spc7 kinetochore protein COG2 PF06148.11 PSC71006.1 - 0.0046 17.0 0.2 0.018 15.1 0.2 2.0 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 XhlA PF10779.9 PSC71006.1 - 0.0068 16.6 0.2 0.027 14.7 0.2 2.0 1 0 0 1 1 1 1 Haemolysin XhlA COG5 PF10392.9 PSC71006.1 - 0.029 14.5 0.1 0.14 12.3 0.1 2.2 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DOG1 PF14144.6 PSC71006.1 - 0.88 9.8 2.8 5.4 7.3 0.5 3.5 3 0 0 3 3 3 0 Seed dormancy control GrpE PF01025.19 PSC71006.1 - 1.8 8.2 5.3 0.28 10.9 0.4 2.1 3 0 0 3 3 3 0 GrpE RRM_1 PF00076.22 PSC71007.1 - 8.4e-22 76.8 0.0 1.4e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) eIF3g PF12353.8 PSC71007.1 - 1.3e-11 44.9 9.6 1.6e-11 44.7 9.0 1.4 1 1 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G RRM_occluded PF16842.5 PSC71007.1 - 0.005 16.7 0.0 0.012 15.4 0.0 1.7 1 0 0 1 1 1 1 Occluded RNA-recognition motif Peptidase_C25 PF01364.18 PSC71007.1 - 0.024 13.8 1.0 0.034 13.3 1.0 1.1 1 0 0 1 1 1 0 Peptidase family C25 Peptidase_M22 PF00814.25 PSC71008.1 - 4.7e-81 272.5 2.7 6.6e-46 157.2 0.0 2.2 1 1 0 2 2 2 2 Glycoprotease family Carbam_trans_N PF02543.15 PSC71008.1 - 5.2e-05 23.1 0.0 0.00011 22.0 0.0 1.5 1 0 0 1 1 1 1 Carbamoyltransferase N-terminus VARLMGL PF14383.6 PSC71008.1 - 0.022 14.3 2.5 0.042 13.4 1.3 2.0 2 0 0 2 2 2 0 DUF761-associated sequence motif Ribonucleas_3_3 PF14622.6 PSC71009.1 - 2.7e-23 82.5 0.0 5.2e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 PSC71009.1 - 6.3e-15 55.7 0.1 1.9e-14 54.2 0.0 1.9 2 0 0 2 2 2 1 Ribonuclease III domain dsrm PF00035.26 PSC71009.1 - 0.0048 17.6 0.0 0.012 16.3 0.0 1.7 1 0 0 1 1 1 1 Double-stranded RNA binding motif TFIIA PF03153.13 PSC71009.1 - 7.3 6.5 11.3 10 6.0 11.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PPR_2 PF13041.6 PSC71010.1 - 4.1e-14 52.5 0.0 0.08 13.2 0.0 4.7 4 0 0 4 4 4 4 PPR repeat family RAP PF08373.10 PSC71010.1 - 7.7e-11 41.9 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.15 PSC71010.1 - 1.5e-09 37.7 0.0 0.2 11.6 0.0 6.0 4 1 3 7 7 7 3 FAST kinase-like protein, subdomain 1 PPR PF01535.20 PSC71010.1 - 1e-07 31.7 0.0 0.024 14.8 0.0 4.3 3 0 0 3 3 3 2 PPR repeat PPR_long PF17177.4 PSC71010.1 - 9.2e-07 28.4 1.5 0.0073 15.7 2.0 2.5 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP Cyclin_C PF02984.19 PSC71010.1 - 8.4e-05 22.6 0.0 0.00025 21.1 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain MTES_1575 PF18741.1 PSC71010.1 - 0.00033 20.7 0.0 0.00073 19.7 0.0 1.5 1 0 0 1 1 1 1 REase_MTES_1575 PPR_1 PF12854.7 PSC71010.1 - 0.011 15.4 0.0 8.1 6.2 0.0 3.5 3 0 0 3 3 3 0 PPR repeat PPR_3 PF13812.6 PSC71010.1 - 0.019 15.0 0.0 21 5.3 0.0 4.0 4 0 0 4 4 4 0 Pentatricopeptide repeat domain PPR_2 PF13041.6 PSC71011.1 - 4.1e-14 52.5 0.0 0.08 13.1 0.0 4.7 4 0 0 4 4 4 4 PPR repeat family RAP PF08373.10 PSC71011.1 - 7.7e-11 41.9 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.15 PSC71011.1 - 1.5e-09 37.7 0.0 0.2 11.6 0.0 6.0 4 1 3 7 7 7 3 FAST kinase-like protein, subdomain 1 PPR PF01535.20 PSC71011.1 - 1e-07 31.7 0.0 0.024 14.8 0.0 4.3 3 0 0 3 3 3 2 PPR repeat PPR_long PF17177.4 PSC71011.1 - 9.3e-07 28.4 1.5 0.0073 15.7 2.0 2.5 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP Cyclin_C PF02984.19 PSC71011.1 - 8.5e-05 22.6 0.0 0.00025 21.1 0.0 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain MTES_1575 PF18741.1 PSC71011.1 - 0.00034 20.7 0.0 0.00073 19.7 0.0 1.5 1 0 0 1 1 1 1 REase_MTES_1575 PPR_1 PF12854.7 PSC71011.1 - 0.011 15.4 0.0 8.1 6.2 0.0 3.5 3 0 0 3 3 3 0 PPR repeat PPR_3 PF13812.6 PSC71011.1 - 0.019 15.0 0.0 21 5.3 0.0 4.0 4 0 0 4 4 4 0 Pentatricopeptide repeat domain DEAD PF00270.29 PSC71012.1 - 2.5e-13 50.1 0.0 6.8e-13 48.8 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase GYF PF02213.16 PSC71012.1 - 2.4e-11 43.1 0.0 4.5e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 GYF domain Helicase_C PF00271.31 PSC71012.1 - 1.8e-06 28.2 0.0 5.2e-06 26.8 0.0 1.7 1 1 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC71012.1 - 0.00028 21.0 0.0 0.00052 20.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF4748 PF15932.5 PSC71013.1 - 0.023 14.4 0.7 0.12 12.1 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4748) DUF4417 PF14386.6 PSC71013.1 - 0.1 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4417) DUF3754 PF12576.8 PSC71014.1 - 1.2e-14 54.5 0.0 1.7e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3754) F-box PF00646.33 PSC71014.1 - 0.005 16.7 0.0 0.015 15.1 0.0 1.8 1 0 0 1 1 1 1 F-box domain DUF2244 PF10003.9 PSC71014.1 - 0.094 12.4 0.7 0.21 11.3 0.7 1.5 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) NHL PF01436.21 PSC71014.1 - 0.23 11.6 0.5 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 NHL repeat Aminotran_5 PF00266.19 PSC71016.1 - 1.1e-90 304.3 0.0 2e-90 303.4 0.0 1.4 1 1 0 1 1 1 1 Aminotransferase class-V MtN3_slv PF03083.16 PSC71016.1 - 5.3e-30 103.3 9.6 1.8e-20 72.8 1.4 3.0 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange DegT_DnrJ_EryC1 PF01041.17 PSC71016.1 - 1.7e-07 30.9 0.2 3.1e-07 30.1 0.2 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 PSC71016.1 - 6.5e-07 28.2 0.0 1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 PSC71016.1 - 1.3e-05 24.6 0.1 2.3e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II NPA PF16469.5 PSC71016.1 - 0.031 14.8 0.0 0.056 14.0 0.0 1.4 1 0 0 1 1 1 0 Nematode polyprotein allergen ABA-1 Methyltransf_22 PF13383.6 PSC71017.1 - 9.3e-21 74.5 0.5 2.7e-20 73.0 0.5 1.6 1 1 0 1 1 1 1 Methyltransferase domain CENP-T_C PF15511.6 PSC71017.1 - 1.9e-07 31.1 0.0 3.1e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Methyltransf_21 PF05050.12 PSC71017.1 - 6e-07 29.6 0.0 1.2e-06 28.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase FkbM domain TAF PF02969.17 PSC71017.1 - 0.0012 19.0 0.1 0.0037 17.4 0.0 1.9 2 0 0 2 2 2 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 PSC71017.1 - 0.0014 19.0 0.0 0.0025 18.2 0.0 1.4 1 0 0 1 1 1 1 CENP-S protein Bromo_TP PF07524.13 PSC71017.1 - 0.0066 16.4 0.0 0.016 15.2 0.0 1.6 1 0 0 1 1 1 1 Bromodomain associated Histone PF00125.24 PSC71017.1 - 0.011 16.1 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC71017.1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.6 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PSC71017.1 - 0.17 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit AI-2E_transport PF01594.16 PSC71018.1 - 1.6e-07 30.8 10.2 1.6e-07 30.8 10.2 2.8 3 0 0 3 3 3 2 AI-2E family transporter CLTH PF10607.9 PSC71019.1 - 2.4e-35 121.6 0.2 3e-35 121.3 0.2 1.1 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 PSC71019.1 - 1.2e-08 34.6 0.1 4.1e-08 32.9 0.0 1.9 2 0 0 2 2 2 1 LisH TINF2_N PF14973.6 PSC71019.1 - 0.0085 16.5 0.5 0.022 15.1 0.1 1.9 2 1 0 2 2 2 1 TERF1-interacting nuclear factor 2 N-terminus TPR_14 PF13428.6 PSC71019.1 - 1.1 10.3 8.1 0.28 12.1 0.6 3.2 3 2 1 4 4 4 0 Tetratricopeptide repeat Sulf_transp PF04143.14 PSC71020.1 - 9.8e-07 28.6 14.9 9.8e-07 28.6 14.9 3.2 4 0 0 4 4 4 2 Sulphur transport WD40 PF00400.32 PSC71020.1 - 0.11 13.4 3.9 15 6.7 0.1 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat RIC3 PF15361.6 PSC71020.1 - 0.53 10.7 1.9 30 5.0 1.0 3.6 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Sulf_transp PF04143.14 PSC71021.1 - 9.8e-07 28.6 14.9 9.8e-07 28.6 14.9 3.2 4 0 0 4 4 4 2 Sulphur transport WD40 PF00400.32 PSC71021.1 - 0.11 13.4 3.9 14 6.7 0.1 3.0 2 0 0 2 2 2 0 WD domain, G-beta repeat RWD PF05773.22 PSC71022.1 - 1.9e-21 76.5 0.0 3.4e-21 75.7 0.0 1.4 1 0 0 1 1 1 1 RWD domain DFRP_C PF16543.5 PSC71022.1 - 9.5e-05 22.8 8.2 0.00041 20.8 8.1 2.2 1 1 0 1 1 1 1 DRG Family Regulatory Proteins, Tma46 LPD5 PF18799.1 PSC71022.1 - 0.0035 17.8 0.1 0.0081 16.6 0.1 1.6 1 0 0 1 1 1 1 Large polyvalent protein-associated domain 5 CNDH2_C PF16858.5 PSC71022.1 - 0.73 9.6 6.4 1.2 9.0 6.4 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Cwf_Cwc_15 PF04889.12 PSC71022.1 - 2 8.1 17.0 3.8 7.2 17.0 1.5 1 1 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Menin PF05053.13 PSC71023.1 - 2.3e-26 92.4 0.0 6.1e-21 74.5 0.0 3.4 2 2 1 3 3 3 2 Menin CCB2_CCB4 PF11152.8 PSC71023.1 - 0.11 11.7 1.9 0.24 10.7 1.6 1.6 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B, CCB2/CCB4 CCDC53 PF10152.9 PSC71023.1 - 0.37 11.2 3.6 0.88 10.0 3.6 1.6 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF5427 PF10310.9 PSC71023.1 - 1.1 8.2 7.9 1.7 7.5 7.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Spc7 PF08317.11 PSC71024.1 - 0.00017 20.6 7.2 0.00017 20.6 7.2 16.8 2 2 16 19 19 19 10 Spc7 kinetochore protein Filament PF00038.21 PSC71024.1 - 0.00051 19.7 28.3 0.00051 19.7 28.3 13.6 1 1 11 12 12 12 5 Intermediate filament protein DUF2205 PF10224.9 PSC71024.1 - 0.064 13.3 0.0 0.064 13.3 0.0 13.3 14 0 0 14 14 14 0 Short coiled-coil protein Motilin_ghrelin PF04644.12 PSC71024.1 - 0.068 13.0 0.1 0.34 10.8 0.1 2.3 1 0 0 1 1 1 0 Motilin/ghrelin DUF1492 PF07374.11 PSC71024.1 - 1.8 8.8 4.2 9.4 6.5 0.4 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1492) Filament PF00038.21 PSC71025.1 - 0.00012 21.8 46.6 0.00056 19.6 28.3 13.6 1 1 9 12 12 12 6 Intermediate filament protein Spc7 PF08317.11 PSC71025.1 - 0.00024 20.1 8.1 0.00024 20.1 8.1 16.5 1 1 12 16 16 16 10 Spc7 kinetochore protein DUF2205 PF10224.9 PSC71025.1 - 0.064 13.3 0.0 0.064 13.3 0.0 13.3 14 0 0 14 14 14 0 Short coiled-coil protein Motilin_ghrelin PF04644.12 PSC71025.1 - 0.068 13.0 0.1 0.34 10.8 0.1 2.3 1 0 0 1 1 1 0 Motilin/ghrelin DUF1492 PF07374.11 PSC71025.1 - 1.7 8.8 4.2 9.4 6.5 0.4 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1492) Cyto_heme_lyase PF01265.17 PSC71026.1 - 5.3e-58 196.9 6.8 3.8e-57 194.1 6.8 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase DUF488 PF04343.13 PSC71027.1 - 5.6e-28 98.0 1.3 1.9e-27 96.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF488 TFIIA PF03153.13 PSC71027.1 - 0.73 9.8 29.0 1 9.3 29.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 PSC71027.1 - 3.3 6.4 9.7 4.3 6.0 9.7 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 PSC71027.1 - 3.5 7.6 5.2 4.7 7.2 5.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SelP_N PF04592.14 PSC71027.1 - 5.6 6.3 18.4 11 5.3 18.4 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Aa_trans PF01490.18 PSC71028.1 - 7.8e-51 173.1 0.0 1.8e-50 171.8 0.0 1.5 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein LRR_8 PF13855.6 PSC71028.1 - 8.4e-08 31.9 0.8 0.00077 19.2 0.3 4.0 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 PSC71028.1 - 0.0025 18.2 6.4 0.0092 16.4 0.2 4.6 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) Glyco_transf_41 PF13844.6 PSC71029.1 - 1.9e-139 465.2 0.0 3e-71 240.3 0.0 2.1 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_1 PF00515.28 PSC71029.1 - 1.1e-51 170.6 36.3 2.3e-06 27.2 0.5 10.6 11 0 0 11 11 10 9 Tetratricopeptide repeat TPR_11 PF13414.6 PSC71029.1 - 6.5e-41 137.8 45.9 1.2e-09 37.7 0.5 10.5 8 4 4 12 12 11 8 TPR repeat TPR_2 PF07719.17 PSC71029.1 - 8.3e-41 134.8 42.3 4.7e-05 23.2 0.0 12.2 12 0 0 12 12 12 9 Tetratricopeptide repeat TPR_8 PF13181.6 PSC71029.1 - 5.4e-37 122.9 16.6 0.0015 18.6 0.0 9.8 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_16 PF13432.6 PSC71029.1 - 4.2e-28 97.7 70.5 1.5e-09 38.3 0.4 9.5 4 2 4 8 8 8 7 Tetratricopeptide repeat TPR_17 PF13431.6 PSC71029.1 - 7.6e-27 91.7 18.7 9.1e-05 22.6 0.1 10.1 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_12 PF13424.6 PSC71029.1 - 1.2e-24 86.4 50.9 4.3e-07 30.1 0.2 8.2 3 3 6 9 9 9 9 Tetratricopeptide repeat TPR_14 PF13428.6 PSC71029.1 - 2.1e-23 81.0 60.5 0.00054 20.5 0.5 11.2 4 2 8 12 12 11 8 Tetratricopeptide repeat TPR_7 PF13176.6 PSC71029.1 - 2.3e-23 80.5 33.6 0.0044 17.0 0.3 10.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_19 PF14559.6 PSC71029.1 - 6.6e-22 77.8 50.9 1.2e-05 25.7 5.9 7.6 5 2 2 7 7 7 6 Tetratricopeptide repeat TPR_6 PF13174.6 PSC71029.1 - 1.3e-12 47.5 29.4 1.7 9.5 0.2 9.9 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_10 PF13374.6 PSC71029.1 - 6.6e-12 44.9 62.9 0.00086 19.1 0.7 10.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_15 PF13429.6 PSC71029.1 - 2.6e-06 26.9 22.1 0.11 11.7 0.0 5.4 2 2 2 5 5 5 3 Tetratricopeptide repeat BTAD PF03704.17 PSC71029.1 - 7.4e-06 26.5 38.8 0.0026 18.2 2.3 5.3 1 1 4 5 5 5 3 Bacterial transcriptional activator domain TPR_9 PF13371.6 PSC71029.1 - 2.1e-05 24.6 47.2 0.074 13.2 1.2 7.0 4 2 4 8 8 7 6 Tetratricopeptide repeat EST1_DNA_bind PF10373.9 PSC71029.1 - 0.00079 19.0 1.3 0.0029 17.1 0.1 2.4 3 0 0 3 3 3 1 Est1 DNA/RNA binding domain Alkyl_sulf_dimr PF14863.6 PSC71029.1 - 0.0075 16.7 15.1 16 6.0 5.6 5.2 3 2 1 4 4 4 0 Alkyl sulfatase dimerisation DUF3856 PF12968.7 PSC71029.1 - 0.057 13.5 7.8 13 5.8 0.0 4.6 3 1 1 4 4 4 0 Domain of Unknown Function (DUF3856) DUF630 PF04783.12 PSC71029.1 - 0.077 13.2 5.9 20 5.5 0.0 4.0 3 0 0 3 3 3 0 Protein of unknown function (DUF630) NARP1 PF12569.8 PSC71029.1 - 0.14 11.0 3.6 17 4.1 0.4 3.8 2 2 2 5 5 5 0 NMDA receptor-regulated protein 1 Fis1_TPR_C PF14853.6 PSC71029.1 - 0.28 11.3 3.9 0.6 10.2 0.2 3.3 3 1 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat ANAPC3 PF12895.7 PSC71029.1 - 0.85 9.9 34.5 0.075 13.3 3.3 5.8 5 1 0 6 6 5 0 Anaphase-promoting complex, cyclosome, subunit 3 SpoIIE PF07228.12 PSC71030.1 - 4.1e-11 43.2 1.1 1.8e-10 41.1 1.1 2.2 1 1 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C_2 PF13672.6 PSC71030.1 - 9.1e-07 28.7 3.9 3.2e-06 26.9 3.9 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C PF00481.21 PSC71030.1 - 0.0017 18.1 0.0 2.2 7.9 0.0 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C VWA PF00092.28 PSC71031.1 - 9e-05 22.8 0.2 0.00064 20.0 0.0 2.1 1 1 1 2 2 2 1 von Willebrand factor type A domain HEAT_2 PF13646.6 PSC71031.1 - 0.0077 16.6 2.2 0.0077 16.6 2.2 7.2 4 2 3 7 7 7 1 HEAT repeats VWA_2 PF13519.6 PSC71031.1 - 0.015 15.9 1.3 2.7 8.7 1.3 3.4 1 1 0 1 1 1 0 von Willebrand factor type A domain Adaptin_N PF01602.20 PSC71031.1 - 0.029 12.9 3.6 0.05 12.2 0.1 2.6 2 1 0 2 2 2 0 Adaptin N terminal region SUIM_assoc PF16619.5 PSC71031.1 - 0.61 10.2 7.9 8.8 6.5 0.2 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HEAT PF02985.22 PSC71031.1 - 7.9 7.0 12.4 19 5.9 0.1 5.8 5 0 0 5 5 5 0 HEAT repeat Histone PF00125.24 PSC71032.1 - 2.9e-54 183.0 1.9 3.2e-54 182.8 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 PSC71032.1 - 0.00013 22.5 1.7 0.00016 22.2 1.7 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 PSC71032.1 - 0.00045 20.5 0.0 0.00069 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 PSC71032.1 - 0.00049 20.2 0.5 0.00074 19.6 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 PSC71032.1 - 0.0052 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PSC71032.1 - 0.016 15.3 0.1 0.031 14.3 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit RRM_1 PF00076.22 PSC71033.1 - 7.8e-09 35.2 0.0 0.00034 20.4 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PQQ_2 PF13360.6 PSC71034.1 - 0.01 15.4 0.1 3.4 7.2 0.0 3.0 3 1 1 4 4 4 0 PQQ-like domain ABC2_membrane PF01061.24 PSC71035.1 - 1.3e-43 148.9 13.0 1.8e-43 148.4 13.0 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PSC71035.1 - 8.4e-22 78.2 0.0 2.2e-21 76.8 0.0 1.7 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 PSC71035.1 - 3.8e-08 32.8 5.4 3.8e-08 32.8 5.4 1.5 1 1 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PSC71035.1 - 0.00018 21.4 0.0 0.53 10.0 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PSC71035.1 - 0.0018 18.7 0.5 0.0037 17.7 0.1 1.8 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 PSC71035.1 - 0.0019 18.1 0.1 0.0038 17.1 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 PSC71035.1 - 0.0026 18.0 0.0 0.0069 16.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.19 PSC71035.1 - 0.0072 15.8 0.0 0.71 9.3 0.0 2.2 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain Dynamin_N PF00350.23 PSC71035.1 - 0.027 14.5 0.1 0.052 13.6 0.1 1.4 1 0 0 1 1 1 0 Dynamin family AAA_23 PF13476.6 PSC71035.1 - 0.033 14.7 0.0 0.062 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 PSC71035.1 - 0.04 13.0 0.1 0.075 12.1 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 PSC71035.1 - 0.04 14.0 0.2 0.088 12.9 0.2 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC2_membrane_2 PF12679.7 PSC71035.1 - 0.05 12.9 11.6 0.88 8.8 11.6 2.2 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_29 PF13555.6 PSC71035.1 - 0.085 12.6 0.1 0.2 11.5 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 PSC71035.1 - 0.1 13.0 0.6 0.31 11.5 0.1 2.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Reprolysin_5 PF13688.6 PSC71035.1 - 0.14 12.3 0.0 0.22 11.6 0.0 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 AAA_25 PF13481.6 PSC71035.1 - 0.17 11.5 0.0 0.31 10.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PSC71035.1 - 0.51 10.6 1.5 0.75 10.0 0.2 1.9 2 0 0 2 2 2 0 AAA domain LapA_dom PF06305.11 PSC71035.1 - 0.53 10.1 3.6 0.55 10.1 0.5 2.6 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Wzz PF02706.15 PSC71035.1 - 1.2 9.5 2.7 11 6.5 0.0 2.9 3 0 0 3 3 2 0 Chain length determinant protein Pkinase PF00069.25 PSC71036.1 - 5.7e-46 157.0 0.0 1e-44 152.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC71036.1 - 4.9e-13 48.9 0.0 1.2e-12 47.7 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase DNA_pol3_delta2 PF13177.6 PSC71036.1 - 5.8e-10 39.2 0.0 1.2e-09 38.2 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.29 PSC71036.1 - 5.8e-07 30.0 0.0 1.8e-06 28.4 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PSC71036.1 - 0.00021 21.0 0.0 0.015 15.1 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PSC71036.1 - 0.00066 20.1 0.7 0.0093 16.4 0.0 2.8 2 2 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 PSC71036.1 - 0.0012 18.1 0.0 0.0029 16.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Rep_fac_C PF08542.11 PSC71036.1 - 0.0016 18.8 0.0 0.0038 17.6 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain DNA_pol3_delta PF06144.13 PSC71036.1 - 0.0072 16.1 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_5 PF07728.14 PSC71036.1 - 0.0088 16.0 0.1 0.028 14.4 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PSC71036.1 - 0.0096 16.2 0.0 0.057 13.7 0.0 2.3 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 PSC71036.1 - 0.015 15.2 0.0 0.026 14.5 0.0 1.5 1 1 0 1 1 1 0 Rad17 P-loop domain Sigma54_activ_2 PF14532.6 PSC71036.1 - 0.029 14.5 0.0 0.084 13.0 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 PSC71036.1 - 0.084 12.3 0.4 3 7.2 0.0 2.5 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 PSC71036.1 - 0.086 13.3 0.0 0.14 12.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 PSC71036.1 - 0.1 12.3 0.0 0.21 11.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain TB2_DP1_HVA22 PF03134.19 PSC71037.1 - 5.7e-17 61.4 4.1 9.7e-17 60.7 4.1 1.4 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Synaptobrevin PF00957.21 PSC71038.1 - 3.3e-29 100.5 0.1 4.5e-29 100.1 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 PSC71038.1 - 5.9e-18 64.7 0.0 8.8e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 PSC71039.1 - 1.4e-30 104.9 0.4 1.9e-30 104.5 0.4 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 PSC71039.1 - 5.1e-18 64.9 0.0 8.7e-18 64.1 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 PSC71040.1 - 3.3e-29 100.5 0.1 4.5e-29 100.1 0.1 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 PSC71040.1 - 5.9e-18 64.7 0.0 8.8e-18 64.1 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain GGACT PF06094.12 PSC71041.1 - 0.0087 16.7 0.0 0.012 16.2 0.0 1.3 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AIG2_2 PF13772.6 PSC71041.1 - 0.12 12.8 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 AIG2-like family MS_channel PF00924.18 PSC71042.1 - 4.7e-36 124.3 0.1 7.7e-36 123.6 0.1 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel MS_channel PF00924.18 PSC71043.1 - 4.7e-36 124.3 0.1 7.7e-36 123.6 0.1 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel JHD PF17811.1 PSC71044.1 - 0.00027 21.4 0.0 0.00089 19.8 0.0 1.8 2 0 0 2 2 2 1 Jumonji helical domain DUF1192 PF06698.11 PSC71044.1 - 0.0043 17.1 1.4 0.0043 17.1 1.4 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) Cupin_8 PF13621.6 PSC71044.1 - 0.15 11.7 0.0 0.94 9.1 0.0 2.0 1 1 0 1 1 1 0 Cupin-like domain JHD PF17811.1 PSC71045.1 - 0.00027 21.4 0.0 0.00089 19.8 0.0 1.8 2 0 0 2 2 2 1 Jumonji helical domain DUF1192 PF06698.11 PSC71045.1 - 0.0043 17.1 1.4 0.0043 17.1 1.4 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1192) Cupin_8 PF13621.6 PSC71045.1 - 0.15 11.7 0.0 0.94 9.1 0.0 2.0 1 1 0 1 1 1 0 Cupin-like domain Peptidase_M20 PF01546.28 PSC71046.1 - 5.1e-28 98.2 0.0 1.2e-27 97.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 WD40 PF00400.32 PSC71046.1 - 1.3e-15 57.5 10.9 0.017 16.0 0.1 8.0 7 0 0 7 7 7 4 WD domain, G-beta repeat GATase_6 PF13522.6 PSC71046.1 - 1.7e-12 47.7 0.0 4.9e-12 46.2 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase domain M20_dimer PF07687.14 PSC71046.1 - 9.2e-09 35.2 0.0 1.9e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Nup160 PF11715.8 PSC71046.1 - 0.071 11.8 0.1 11 4.5 0.0 3.5 4 0 0 4 4 4 0 Nucleoporin Nup120/160 Metallophos_2 PF12850.7 PSC71047.1 - 6.1e-20 72.0 0.3 1.2e-19 71.2 0.3 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain FATC PF02260.20 PSC71047.1 - 6.4e-12 45.1 0.1 1.1e-11 44.3 0.1 1.3 1 0 0 1 1 1 1 FATC domain Metallophos PF00149.28 PSC71047.1 - 0.017 15.6 4.7 0.24 11.9 0.1 2.3 1 1 1 2 2 2 0 Calcineurin-like phosphoesterase Cyclin_N PF00134.23 PSC71048.1 - 4e-12 46.0 0.3 9.4e-12 44.8 0.3 1.6 1 1 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 PSC71048.1 - 5.7e-11 42.6 0.0 1.6e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain Polysacc_deac_1 PF01522.21 PSC71048.1 - 9.5e-06 25.5 0.0 2e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Aconitase_C PF00694.19 PSC71049.1 - 5.7e-17 62.3 0.0 1e-16 61.5 0.0 1.5 1 1 0 1 1 1 1 Aconitase C-terminal domain Aconitase_2_N PF06434.13 PSC71049.1 - 0.0015 18.2 0.0 0.062 12.9 0.0 2.1 1 1 0 1 1 1 1 Aconitate hydratase 2 N-terminus MmgE_PrpD PF03972.14 PSC71049.1 - 0.061 11.9 1.8 0.096 11.2 0.1 1.8 2 0 0 2 2 2 0 MmgE/PrpD family Arm PF00514.23 PSC71050.1 - 2e-38 129.3 5.1 2e-07 30.8 0.0 8.7 8 1 0 8 8 8 6 Armadillo/beta-catenin-like repeat BTB PF00651.31 PSC71050.1 - 1.4e-22 80.0 0.2 3.6e-22 78.7 0.0 1.8 2 0 0 2 2 1 1 BTB/POZ domain HEAT_2 PF13646.6 PSC71050.1 - 1.7e-15 57.1 8.0 1.8e-05 25.0 0.1 5.6 4 1 5 9 9 8 6 HEAT repeats HEAT PF02985.22 PSC71050.1 - 4.3e-13 48.3 3.8 0.0052 16.9 0.0 7.2 6 1 0 6 6 6 3 HEAT repeat Atx10homo_assoc PF09759.9 PSC71050.1 - 1.3e-09 37.9 0.6 0.00045 20.2 0.0 5.1 4 2 2 6 6 5 3 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 PSC71050.1 - 1.6e-08 34.8 6.2 0.00013 22.4 0.2 5.7 4 1 2 6 6 6 2 HEAT-like repeat DUF3361 PF11841.8 PSC71050.1 - 7.6e-07 29.2 0.1 1.9 8.4 0.0 4.0 3 1 0 4 4 4 3 Domain of unknown function (DUF3361) DUF5578 PF17741.1 PSC71050.1 - 0.00026 20.5 0.1 0.014 14.8 0.0 2.9 2 1 1 3 3 3 1 Family of unknown function (DUF5578) Cnd1 PF12717.7 PSC71050.1 - 0.00035 20.7 0.8 0.019 15.0 0.0 3.3 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.13 PSC71050.1 - 0.00096 18.7 0.1 2.7 7.4 0.0 2.9 1 1 2 3 3 3 3 Armadillo-like Adaptin_N PF01602.20 PSC71050.1 - 0.0021 16.7 0.0 0.12 10.9 0.0 2.9 1 1 2 3 3 3 1 Adaptin N terminal region V-ATPase_H_N PF03224.14 PSC71050.1 - 0.013 14.9 0.1 0.13 11.5 0.1 2.5 1 1 0 1 1 1 0 V-ATPase subunit H V-ATPase_H_C PF11698.8 PSC71050.1 - 0.013 15.6 0.0 1.1 9.4 0.0 3.1 3 0 0 3 3 3 0 V-ATPase subunit H Skp1_POZ PF03931.15 PSC71050.1 - 0.02 15.0 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain Arm PF00514.23 PSC71051.1 - 1.8e-36 123.0 5.4 2e-07 30.8 0.0 8.7 8 1 0 8 8 8 6 Armadillo/beta-catenin-like repeat BTB PF00651.31 PSC71051.1 - 1.4e-22 80.0 0.2 3.6e-22 78.7 0.0 1.8 2 0 0 2 2 1 1 BTB/POZ domain HEAT_2 PF13646.6 PSC71051.1 - 6.3e-15 55.3 9.1 3.4e-05 24.1 0.1 5.6 4 1 5 9 9 8 6 HEAT repeats HEAT PF02985.22 PSC71051.1 - 2.1e-13 49.3 3.4 0.0033 17.5 0.0 7.1 6 1 0 6 6 6 3 HEAT repeat Atx10homo_assoc PF09759.9 PSC71051.1 - 3.8e-13 49.3 0.5 0.00046 20.2 0.0 5.2 4 2 2 6 6 5 4 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 PSC71051.1 - 7e-09 36.0 6.3 0.00012 22.5 0.2 5.7 4 1 2 6 6 6 2 HEAT-like repeat DUF3361 PF11841.8 PSC71051.1 - 7.9e-07 29.1 0.1 1.8 8.5 0.0 3.9 3 1 1 4 4 4 3 Domain of unknown function (DUF3361) DUF5578 PF17741.1 PSC71051.1 - 0.00028 20.4 0.1 0.015 14.7 0.0 2.9 2 1 1 3 3 3 1 Family of unknown function (DUF5578) Cnd1 PF12717.7 PSC71051.1 - 0.00035 20.6 0.6 0.023 14.8 0.0 3.3 3 1 0 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.13 PSC71051.1 - 0.0014 18.1 0.1 1.7 8.1 0.1 2.9 1 1 2 3 3 3 3 Armadillo-like Adaptin_N PF01602.20 PSC71051.1 - 0.0041 15.7 0.0 0.096 11.2 0.0 2.8 1 1 2 3 3 3 1 Adaptin N terminal region V-ATPase_H_C PF11698.8 PSC71051.1 - 0.018 15.2 0.0 1.1 9.4 0.0 3.0 3 0 0 3 3 3 0 V-ATPase subunit H Skp1_POZ PF03931.15 PSC71051.1 - 0.02 15.1 0.0 0.052 13.7 0.0 1.7 1 0 0 1 1 1 0 Skp1 family, tetramerisation domain zf-RING_2 PF13639.6 PSC71052.1 - 2.2e-07 31.1 6.9 5.3e-07 29.9 6.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PSC71052.1 - 4.6e-05 23.2 6.8 0.0001 22.1 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC71052.1 - 9.7e-05 22.3 6.5 0.00018 21.4 6.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 PSC71052.1 - 0.00037 20.2 5.2 0.00087 19.0 5.2 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PSC71052.1 - 0.00073 19.3 8.2 0.0017 18.1 8.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 PSC71052.1 - 0.042 13.5 7.2 0.056 13.1 4.6 2.5 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type zf-rbx1 PF12678.7 PSC71052.1 - 0.059 13.7 6.5 0.16 12.3 6.5 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 PSC71052.1 - 0.099 12.8 6.2 0.19 11.9 6.2 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 PSC71052.1 - 0.16 12.0 3.9 0.07 13.2 0.9 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 PSC71052.1 - 0.38 10.6 6.2 0.78 9.7 6.2 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MIF4G PF02854.19 PSC71053.1 - 2.8e-47 161.1 0.0 2.7e-28 99.1 0.0 3.2 3 0 0 3 3 3 3 MIF4G domain Upf2 PF04050.14 PSC71053.1 - 1.3e-15 58.3 0.0 3.2e-15 57.0 0.0 1.7 1 0 0 1 1 1 1 Up-frameshift suppressor 2 MatE PF01554.18 PSC71054.1 - 3.2e-40 137.4 31.9 4e-21 75.3 10.7 2.3 2 0 0 2 2 2 2 MatE MatE PF01554.18 PSC71055.1 - 2.5e-40 137.8 31.9 3.5e-21 75.5 10.7 2.3 2 0 0 2 2 2 2 MatE adh_short PF00106.25 PSC71056.1 - 5.7e-37 127.1 4.6 2.7e-20 72.6 0.3 3.2 3 0 0 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 PSC71056.1 - 2.1e-35 122.4 0.7 2.2e-17 63.4 1.2 2.6 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase ADH_zinc_N PF00107.26 PSC71056.1 - 6.4e-22 77.9 0.1 1.7e-21 76.6 0.1 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PSC71056.1 - 8.7e-19 68.9 0.1 2.4e-18 67.5 0.0 1.9 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PSC71056.1 - 7.3e-07 29.0 0.0 1.8e-06 27.8 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain KR PF08659.10 PSC71056.1 - 0.024 14.5 1.2 0.024 14.5 1.2 2.0 3 0 0 3 3 3 0 KR domain Sacchrp_dh_NADP PF03435.18 PSC71056.1 - 0.044 14.0 0.2 0.4 11.0 0.1 2.3 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Sacchrp_dh_NADP PF03435.18 PSC71057.1 - 2.3e-15 57.0 0.0 5.8e-15 55.7 0.0 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Phage_integrase PF00589.22 PSC71057.1 - 7.2e-05 22.6 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Phage integrase family NAD_binding_10 PF13460.6 PSC71057.1 - 0.00078 19.4 0.0 0.0022 17.9 0.0 1.8 2 0 0 2 2 2 1 NAD(P)H-binding Shikimate_DH PF01488.20 PSC71057.1 - 0.024 14.7 0.0 0.047 13.7 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NmrA PF05368.13 PSC71057.1 - 0.025 14.1 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family adh_short PF00106.25 PSC71057.1 - 0.089 12.2 0.0 0.17 11.3 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase TGT_C1 PF14809.6 PSC71057.1 - 0.12 12.7 0.1 0.5 10.7 0.0 2.0 2 0 0 2 2 2 0 C1 domain of tRNA-guanine transglycosylase dimerisation DUF3490 PF11995.8 PSC71057.1 - 0.18 11.6 0.1 0.37 10.6 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) Ank_2 PF12796.7 PSC71058.1 - 4.3e-12 46.5 8.7 8.7e-07 29.4 2.1 2.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC71058.1 - 1.9e-06 28.3 8.9 0.00049 20.6 1.1 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC71058.1 - 2.7e-06 27.5 5.0 0.022 15.1 0.8 3.3 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC71058.1 - 1.8e-05 24.7 10.3 0.031 14.8 0.1 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 PSC71058.1 - 0.00019 21.7 1.3 0.00019 21.7 1.3 4.0 4 1 0 4 4 4 1 Ankyrin repeat DNA_pol3_gamma3 PF12169.8 PSC71058.1 - 0.022 14.7 1.0 0.39 10.6 0.1 2.2 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III Ank_2 PF12796.7 PSC71059.1 - 4.3e-12 46.5 8.7 8.7e-07 29.4 2.1 2.4 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC71059.1 - 1.9e-06 28.3 8.9 0.00049 20.6 1.1 3.7 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC71059.1 - 2.7e-06 27.5 5.0 0.022 15.1 0.8 3.3 2 2 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC71059.1 - 1.8e-05 24.7 10.3 0.031 14.8 0.1 4.7 5 0 0 5 5 5 3 Ankyrin repeat Ank PF00023.30 PSC71059.1 - 0.00019 21.7 1.3 0.00019 21.7 1.3 4.0 4 1 0 4 4 4 1 Ankyrin repeat DNA_pol3_gamma3 PF12169.8 PSC71059.1 - 0.022 14.7 1.0 0.39 10.6 0.1 2.2 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III AAA_18 PF13238.6 PSC71060.1 - 3.8e-05 24.2 0.4 0.0034 17.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain CRR7 PF12095.8 PSC71060.1 - 2.1 8.8 3.6 12 6.4 0.1 3.5 3 1 0 3 3 3 0 Protein CHLORORESPIRATORY REDUCTION 7 AAA_18 PF13238.6 PSC71061.1 - 3.9e-05 24.2 0.4 0.0034 17.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain G10 PF01125.17 PSC71064.1 - 7.5e-51 171.7 1.7 9.5e-51 171.4 1.7 1.1 1 0 0 1 1 1 1 G10 protein ResIII PF04851.15 PSC71065.1 - 4e-17 62.7 0.0 6.5e-17 62.1 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PSC71065.1 - 4.3e-17 62.4 0.2 1.9e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC71065.1 - 5.7e-14 52.4 0.0 1.3e-13 51.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Peptidase_S74 PF13884.6 PSC71065.1 - 2.4e-05 24.6 0.0 6.4e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Chaperone of endosialidase PhoH PF02562.16 PSC71065.1 - 0.00049 19.6 0.1 0.0011 18.5 0.1 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA_22 PF13401.6 PSC71065.1 - 0.0043 17.3 0.5 0.96 9.7 0.1 3.1 1 1 1 2 2 2 1 AAA domain AAA_25 PF13481.6 PSC71065.1 - 0.0052 16.4 0.9 0.025 14.2 0.5 2.4 1 1 1 2 2 2 1 AAA domain RNA_GG_bind PF10258.9 PSC71065.1 - 0.0096 15.9 0.0 0.045 13.8 0.0 2.0 2 0 0 2 2 2 1 PHAX RNA-binding domain Piwi PF02171.17 PSC71066.1 - 2.1e-93 312.9 0.0 2.8e-93 312.5 0.0 1.2 1 0 0 1 1 1 1 Piwi domain Ribosomal_L21e PF01157.18 PSC71066.1 - 1.1e-41 140.7 4.8 2.8e-41 139.5 4.8 1.7 1 0 0 1 1 1 1 Ribosomal protein L21e PAZ PF02170.22 PSC71066.1 - 2.6e-20 72.6 0.0 4.6e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 PSC71066.1 - 2.3e-16 59.2 0.0 5e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 PSC71066.1 - 2.3e-15 57.4 0.0 4.9e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 PSC71066.1 - 3.2e-09 37.0 0.0 1e-08 35.4 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 PSC71066.1 - 4.5e-06 26.8 0.0 1.3e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute DUF4936 PF16290.5 PSC71066.1 - 7.7 7.3 6.0 20 5.9 1.4 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4936) Piwi PF02171.17 PSC71067.1 - 2.1e-93 312.9 0.0 2.8e-93 312.5 0.0 1.2 1 0 0 1 1 1 1 Piwi domain Ribosomal_L21e PF01157.18 PSC71067.1 - 1.1e-41 140.7 4.8 2.8e-41 139.5 4.8 1.7 1 0 0 1 1 1 1 Ribosomal protein L21e PAZ PF02170.22 PSC71067.1 - 2.6e-20 72.6 0.0 4.6e-20 71.8 0.0 1.3 1 0 0 1 1 1 1 PAZ domain ArgoL1 PF08699.10 PSC71067.1 - 2.3e-16 59.2 0.0 5e-16 58.1 0.0 1.6 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 PSC71067.1 - 2.3e-15 57.4 0.0 4.9e-15 56.3 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of argonaute ArgoL2 PF16488.5 PSC71067.1 - 3.2e-09 37.0 0.0 1e-08 35.4 0.0 2.0 1 0 0 1 1 1 1 Argonaute linker 2 domain ArgoMid PF16487.5 PSC71067.1 - 4.5e-06 26.8 0.0 1.3e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Mid domain of argonaute DUF4936 PF16290.5 PSC71067.1 - 7.7 7.3 6.0 20 5.9 1.4 3.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4936) Chloroa_b-bind PF00504.21 PSC71068.1 - 2.5e-40 138.7 0.3 3.2e-40 138.3 0.3 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein SprT-like PF10263.9 PSC71069.1 - 1.2e-23 83.1 0.0 3.4e-23 81.6 0.0 1.7 2 0 0 2 2 2 1 SprT-like family Radial_spoke PF04712.12 PSC71069.1 - 0.66 8.8 1.9 5.9 5.7 0.0 2.1 2 0 0 2 2 2 0 Radial spokehead-like protein DTHCT PF08070.11 PSC71069.1 - 2.1 9.1 5.5 2.3 9.0 1.4 2.5 2 0 0 2 2 2 0 DTHCT (NUC029) region Amidohydro_1 PF01979.20 PSC71070.1 - 9e-15 54.8 0.0 8.7e-08 31.9 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_3 PF07969.11 PSC71070.1 - 5.3e-14 52.6 0.9 6.2e-08 32.5 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Peptidase_M11 PF05548.11 PSC71071.1 - 8.5e-19 67.8 0.0 1.2e-18 67.3 0.0 1.1 1 0 0 1 1 1 1 Gametolysin peptidase M11 Peptidase_M66 PF10462.9 PSC71071.1 - 0.038 12.9 1.7 0.056 12.4 1.7 1.2 1 0 0 1 1 1 0 Peptidase M66 Hydrolase PF00702.26 PSC71072.1 - 0.00013 22.4 0.0 0.00026 21.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 PSC71072.1 - 0.0033 17.5 0.0 0.0086 16.2 0.0 1.9 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase HAD PF12710.7 PSC71072.1 - 0.0074 16.7 0.1 0.016 15.6 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase TFA2_Winged_2 PF18121.1 PSC71072.1 - 0.016 14.9 0.0 0.09 12.5 0.0 2.1 2 0 0 2 2 2 0 TFA2 Winged helix domain 2 PELOTA_1 PF15608.6 PSC71072.1 - 0.056 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 PELOTA RNA binding domain Bromodomain PF00439.25 PSC71073.1 - 6.7e-64 212.0 0.0 4.7e-20 71.4 0.0 4.3 4 0 0 4 4 4 4 Bromodomain PHD PF00628.29 PSC71073.1 - 3.9e-20 71.5 33.0 2.5e-08 33.7 6.3 3.9 3 0 0 3 3 3 3 PHD-finger DDT PF02791.17 PSC71073.1 - 1e-11 44.9 0.1 2.2e-11 43.9 0.1 1.6 1 0 0 1 1 1 1 DDT domain zf-HC5HC2H PF13771.6 PSC71073.1 - 0.052 13.8 26.1 0.09 13.0 4.0 3.7 3 0 0 3 3 3 0 PHD-like zinc-binding domain WHIM1 PF15612.6 PSC71073.1 - 0.16 11.6 0.0 0.32 10.6 0.0 1.5 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 zf-HC5HC2H_2 PF13832.6 PSC71073.1 - 1.3 9.3 20.8 0.27 11.4 1.0 3.6 3 0 0 3 3 3 0 PHD-zinc-finger like domain PHD_4 PF16866.5 PSC71073.1 - 3.5 7.8 32.7 1.9 8.7 7.4 4.2 3 1 0 3 3 3 0 PHD-finger TMF_TATA_bd PF12325.8 PSC71074.1 - 0.096 12.9 0.3 0.17 12.1 0.3 1.4 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding AAA_13 PF13166.6 PSC71074.1 - 0.1 11.2 0.1 0.14 10.8 0.1 1.1 1 0 0 1 1 1 0 AAA domain Med9 PF07544.13 PSC71074.1 - 0.14 12.3 0.3 0.29 11.3 0.3 1.5 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 ABC_tran_CTD PF16326.5 PSC71074.1 - 3.4 8.0 6.3 11 6.4 3.1 2.8 2 1 0 2 2 2 0 ABC transporter C-terminal domain SlyX PF04102.12 PSC71074.1 - 8.4 7.1 9.2 3.6 8.3 0.3 3.2 2 2 1 3 3 3 0 SlyX Pyridoxal_deC PF00282.19 PSC71075.1 - 5.1e-24 84.7 0.0 1e-23 83.7 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 PSC71075.1 - 0.024 13.6 0.0 0.04 12.9 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Glyco_hydro_130 PF04041.13 PSC71076.1 - 0.012 14.5 0.0 0.073 12.0 0.0 2.0 2 0 0 2 2 2 0 beta-1,4-mannooligosaccharide phosphorylase Fibrinogen_C PF00147.18 PSC71076.1 - 0.062 13.1 0.3 0.14 12.0 0.2 1.6 2 0 0 2 2 2 0 Fibrinogen beta and gamma chains, C-terminal globular domain Serinc PF03348.15 PSC71077.1 - 7.4e-73 245.9 18.7 7.5e-71 239.3 18.7 2.0 1 1 0 1 1 1 1 Serine incorporator (Serinc) EamA PF00892.20 PSC71079.1 - 8.7e-12 45.4 38.1 1.1e-06 28.8 10.3 3.2 3 0 0 3 3 3 3 EamA-like transporter family PUNUT PF16913.5 PSC71079.1 - 5.1e-05 22.7 3.1 8.7e-05 21.9 3.1 1.3 1 0 0 1 1 1 1 Purine nucleobase transmembrane transport SLC35F PF06027.12 PSC71079.1 - 6.1e-05 22.7 2.7 8.6e-05 22.2 1.8 1.6 2 0 0 2 2 2 1 Solute carrier family 35 TPT PF03151.16 PSC71079.1 - 0.00026 20.5 5.6 0.00042 19.7 4.8 1.5 1 1 0 1 1 1 1 Triose-phosphate Transporter family COX14 PF14880.6 PSC71079.1 - 0.77 9.7 4.2 21 5.0 2.8 3.0 2 1 0 2 2 2 0 Cytochrome oxidase c assembly FAD_binding_2 PF00890.24 PSC71080.1 - 2.3e-121 405.8 4.0 3.4e-121 405.2 4.0 1.3 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 PSC71080.1 - 1.5e-42 144.6 1.9 2.6e-42 143.8 1.9 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 PSC71080.1 - 0.0086 15.3 0.4 1.3 8.2 0.1 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 PSC71080.1 - 0.02 14.0 1.4 0.37 9.8 2.3 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 PSC71080.1 - 0.027 13.7 0.4 0.053 12.8 0.4 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 PSC71080.1 - 0.027 13.7 0.3 0.059 12.6 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PSC71081.1 - 2.3e-121 405.8 4.0 3.4e-121 405.2 4.0 1.3 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 PSC71081.1 - 1.5e-42 144.6 1.9 2.6e-42 143.8 1.9 1.3 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Thi4 PF01946.17 PSC71081.1 - 0.0085 15.3 0.4 1.3 8.2 0.1 2.5 2 0 0 2 2 2 2 Thi4 family GIDA PF01134.22 PSC71081.1 - 0.02 14.0 1.4 0.37 9.8 2.3 2.1 2 0 0 2 2 2 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 PSC71081.1 - 0.027 13.7 0.4 0.053 12.8 0.4 1.5 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_2 PF07992.14 PSC71081.1 - 0.027 13.7 0.3 0.059 12.6 0.3 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Serglycin PF04360.12 PSC71082.1 - 0.46 10.4 3.7 0.69 9.9 3.7 1.3 1 0 0 1 1 1 0 Serglycin Halo_GVPC PF05465.13 PSC71082.1 - 0.57 10.5 3.0 7.4 6.9 0.5 2.8 2 0 0 2 2 2 0 Halobacterial gas vesicle protein C (GVPC) repeat GHMP_kinases_C PF08544.13 PSC71082.1 - 2.3 8.6 8.5 5.1 7.5 6.9 2.5 1 1 1 2 2 2 0 GHMP kinases C terminal Ank_5 PF13857.6 PSC71083.1 - 1.4e-31 108.2 10.9 4.8e-11 42.7 0.6 5.4 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 PSC71083.1 - 1.3e-29 102.6 1.1 3e-10 40.6 0.1 3.9 3 1 0 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC71083.1 - 1.2e-26 92.7 0.7 6.9e-07 29.7 0.0 5.6 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 PSC71083.1 - 4.3e-21 74.3 14.8 7.2e-07 29.4 0.1 6.3 6 0 0 6 6 6 4 Ankyrin repeat Ank_3 PF13606.6 PSC71083.1 - 1.6e-20 71.0 3.3 4.1e-05 23.6 0.0 6.1 6 0 0 6 6 6 4 Ankyrin repeat GYF_2 PF14237.6 PSC71083.1 - 2.8e-09 36.6 2.0 1e-08 34.8 0.1 2.4 2 0 0 2 2 2 1 GYF domain 2 zf-RING_4 PF14570.6 PSC71084.1 - 3.8e-17 61.8 11.8 6.5e-17 61.1 11.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 PSC71084.1 - 8e-06 25.6 7.3 1.4e-05 24.8 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 PSC71084.1 - 5.4e-05 22.7 0.2 8.5e-05 22.0 0.2 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.6 PSC71084.1 - 0.00049 20.4 10.3 0.0008 19.7 10.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-UDP PF14569.6 PSC71084.1 - 0.00079 19.5 2.8 0.0015 18.6 2.8 1.3 1 0 0 1 1 1 1 Zinc-binding RING-finger Baculo_IE-1 PF05290.11 PSC71084.1 - 0.015 15.2 3.3 0.025 14.5 3.3 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 PSC71084.1 - 0.045 13.6 7.9 4.4 7.2 8.3 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 PSC71084.1 - 0.44 10.5 10.4 0.76 9.7 10.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC71084.1 - 0.67 10.0 8.7 1.1 9.2 8.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_5 PF17121.5 PSC71084.1 - 1.6 8.6 7.3 2.9 7.8 7.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.11 PSC71084.1 - 1.7 8.8 9.3 3.7 7.7 9.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_2 PF13923.6 PSC71084.1 - 2 8.3 10.1 3.6 7.5 10.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 PSC71085.1 - 2.7e-17 62.3 11.8 4.8e-17 61.5 11.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 PSC71085.1 - 5.5e-06 26.1 7.3 1e-05 25.3 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.12 PSC71085.1 - 4.7e-05 22.9 0.2 7e-05 22.3 0.2 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_2 PF13639.6 PSC71085.1 - 0.00035 20.8 10.3 0.00059 20.1 10.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-UDP PF14569.6 PSC71085.1 - 0.00056 20.0 2.8 0.0011 19.0 2.8 1.4 1 0 0 1 1 1 1 Zinc-binding RING-finger Baculo_IE-1 PF05290.11 PSC71085.1 - 0.018 15.0 3.8 0.029 14.3 3.8 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.6 PSC71085.1 - 0.024 14.5 7.8 0.22 11.4 3.3 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 PSC71085.1 - 0.31 10.9 10.4 0.56 10.1 10.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC71085.1 - 0.47 10.4 8.7 0.84 9.6 8.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PSC71085.1 - 0.94 9.4 9.6 1.8 8.5 9.6 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_5 PF17121.5 PSC71085.1 - 1.2 9.1 7.3 2.2 8.3 7.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.11 PSC71085.1 - 1.2 9.2 9.3 2.7 8.1 9.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) OrfB_Zn_ribbon PF07282.11 PSC71085.1 - 2.9 7.9 4.9 8.7 6.3 0.6 2.3 1 1 1 2 2 2 0 Putative transposase DNA-binding domain CK2S PF15011.6 PSC71086.1 - 0.015 15.2 0.0 0.02 14.8 0.0 1.2 1 0 0 1 1 1 0 Casein Kinase 2 substrate FAA_hydro_N_2 PF18288.1 PSC71086.1 - 0.15 12.5 8.7 3.6 8.1 0.4 2.8 3 0 0 3 3 3 0 Fumarylacetoacetase N-terminal domain 2 DHO_dh PF01180.21 PSC71087.1 - 9.2e-30 103.9 0.0 1.1e-29 103.6 0.0 1.1 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Dus PF01207.17 PSC71087.1 - 0.028 13.5 0.1 0.041 13.0 0.1 1.2 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Histone_H2A_C PF16211.5 PSC71088.1 - 6e-20 70.7 1.8 1.2e-19 69.7 1.8 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 PSC71088.1 - 1.8e-15 57.4 0.0 2.3e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC71088.1 - 1.5e-05 25.1 0.0 2.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Hemerythrin PF01814.23 PSC71089.1 - 1.6e-12 48.2 9.0 2.5e-12 47.5 9.0 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Macoilin PF09726.9 PSC71089.1 - 0.051 12.2 2.0 0.064 11.8 2.0 1.1 1 0 0 1 1 1 0 Macoilin family DUF2457 PF10446.9 PSC71089.1 - 0.62 9.2 11.0 1.1 8.3 11.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2457) Chloroa_b-bind PF00504.21 PSC71090.1 - 3e-45 154.6 0.1 4.4e-45 154.1 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein CENP-T_C PF15511.6 PSC71092.1 - 2e-08 34.3 0.1 2.5e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PSC71092.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 PSC71092.1 - 0.00022 21.3 0.1 0.00031 20.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 PSC71092.1 - 0.0011 18.9 0.1 0.0017 18.4 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 PSC71092.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PSC71092.1 - 0.0015 18.9 0.1 0.0017 18.8 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 PSC71092.1 - 0.033 14.3 0.0 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF167 PF02594.16 PSC71093.1 - 5.7e-19 68.0 0.0 1.9e-18 66.3 0.0 2.0 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 rve PF00665.26 PSC71093.1 - 6e-19 68.4 0.0 2.1e-18 66.7 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 PSC71093.1 - 0.0078 16.0 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain AAA_25 PF13481.6 PSC71093.1 - 0.039 13.5 2.7 3.1 7.3 0.3 3.4 2 1 0 2 2 2 0 AAA domain PP2C PF00481.21 PSC71094.1 - 4.6e-37 128.1 0.0 6e-37 127.7 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PSC71094.1 - 0.024 14.3 0.4 0.05 13.2 0.2 1.7 2 0 0 2 2 2 0 Protein phosphatase 2C CheY-binding PF09078.11 PSC71094.1 - 0.18 11.9 0.0 0.37 10.9 0.0 1.5 1 0 0 1 1 1 0 CheY binding p450 PF00067.22 PSC71095.1 - 9.9e-66 222.4 0.0 1.6e-65 221.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 PSC71095.1 - 3.5e-40 137.5 0.1 1.4e-39 135.5 0.6 1.8 2 0 0 2 2 2 1 short chain dehydrogenase PAP_fibrillin PF04755.12 PSC71095.1 - 1.3e-33 116.6 0.4 4.7e-32 111.6 0.4 2.2 1 1 0 1 1 1 1 PAP_fibrillin adh_short_C2 PF13561.6 PSC71095.1 - 2.2e-30 105.9 1.1 4.5e-30 104.9 1.1 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC71095.1 - 1e-08 35.3 0.1 2.1e-08 34.3 0.1 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PSC71095.1 - 0.001 18.6 0.1 0.0035 16.8 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family UPF0052 PF01933.18 PSC71096.1 - 3.3e-52 177.5 0.0 4.2e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family UPF0052 TPR_7 PF13176.6 PSC71097.1 - 9.6e-06 25.3 0.3 0.042 13.9 0.3 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 PSC71097.1 - 4.1e-05 23.9 5.3 0.00027 21.4 1.1 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 PSC71097.1 - 0.00035 20.5 5.4 0.014 15.4 1.6 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 PSC71097.1 - 0.00063 19.5 3.5 0.04 13.7 1.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 PSC71097.1 - 0.0026 18.2 3.0 0.0026 18.2 3.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 PSC71097.1 - 0.01 16.0 0.9 0.06 13.6 0.6 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 PSC71097.1 - 0.023 15.0 3.8 1.3 9.4 0.8 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 PSC71097.1 - 0.079 13.1 2.6 4.4 7.5 0.5 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 PSC71097.1 - 1.2 10.1 6.8 40 5.4 0.1 3.7 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_3 PF07720.12 PSC71097.1 - 2.3 8.3 4.6 0.48 10.5 0.3 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat RsfS PF02410.15 PSC71098.1 - 2.1e-22 79.4 0.0 5e-22 78.2 0.0 1.7 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation SAP PF02037.27 PSC71098.1 - 7.6e-05 22.4 2.5 0.00016 21.3 2.5 1.6 1 0 0 1 1 1 1 SAP domain Amidase PF01425.21 PSC71099.1 - 8e-21 74.5 9.9 1.7e-14 53.6 7.4 2.3 2 0 0 2 2 2 2 Amidase TPR_1 PF00515.28 PSC71099.1 - 9.9e-14 50.5 15.6 8.1e-05 22.3 4.5 3.8 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PSC71099.1 - 6.1e-11 41.6 25.6 0.00013 21.8 0.9 5.1 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 PSC71099.1 - 8.4e-08 31.8 7.7 5.1e-07 29.3 3.4 2.7 2 0 0 2 2 2 1 TPR repeat TPR_8 PF13181.6 PSC71099.1 - 3.5e-07 29.9 9.0 0.04 14.1 2.5 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 PSC71099.1 - 1.3e-05 25.8 7.3 1.3e-05 25.8 7.3 7.1 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 PSC71099.1 - 0.0028 17.8 17.6 0.14 12.4 2.7 4.7 2 1 2 4 4 4 2 Tetratricopeptide repeat DUF2937 PF11157.8 PSC71099.1 - 0.03 14.1 3.5 0.21 11.3 1.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2937) TPR_6 PF13174.6 PSC71099.1 - 0.047 14.3 12.4 0.28 11.9 0.2 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.6 PSC71099.1 - 0.056 13.7 16.4 0.059 13.7 4.2 3.7 2 1 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PSC71099.1 - 0.075 13.1 13.4 0.67 10.1 2.1 4.1 4 1 1 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 PSC71099.1 - 0.22 12.1 21.7 0.09 13.3 4.3 4.1 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF3975 PF13126.6 PSC71099.1 - 0.26 11.8 0.0 0.47 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3975) TPR_17 PF13431.6 PSC71099.1 - 0.92 10.0 6.7 0.23 11.9 1.3 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 PSC71099.1 - 1.7 8.6 20.4 0.14 12.1 2.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat REJ PF02010.15 PSC71100.1 - 4.4e-19 68.6 0.0 7.4e-17 61.3 0.0 2.2 1 1 1 2 2 2 2 REJ domain HhH-GPD PF00730.25 PSC71100.1 - 2.6e-16 60.0 0.0 9.1e-15 55.0 0.0 3.0 2 1 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein Ank_2 PF12796.7 PSC71100.1 - 1.8e-13 50.8 17.0 1.9e-08 34.8 3.7 3.5 3 0 0 3 3 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC71100.1 - 2.1e-10 40.6 12.1 1.3e-05 25.4 1.6 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC71100.1 - 6.1e-10 39.4 14.6 0.0016 19.0 0.2 4.7 3 1 2 5 5 5 4 Ankyrin repeats (many copies) U-box PF04564.15 PSC71100.1 - 1.7e-09 37.7 0.0 4.4e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 U-box domain Ank_3 PF13606.6 PSC71100.1 - 0.00096 19.4 4.9 0.49 11.1 0.1 4.8 4 0 0 4 4 4 1 Ankyrin repeat zf-Nse PF11789.8 PSC71100.1 - 0.0011 18.7 0.0 0.0033 17.2 0.0 1.8 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit SAP PF02037.27 PSC71100.1 - 0.015 15.0 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 SAP domain Ank PF00023.30 PSC71100.1 - 0.018 15.4 16.2 3 8.5 0.7 4.9 4 0 0 4 4 3 0 Ankyrin repeat Phytoreo_P8 PF07124.11 PSC71100.1 - 0.033 13.1 0.3 0.077 11.9 0.3 1.5 1 0 0 1 1 1 0 Phytoreovirus outer capsid protein P8 zf-NOSIP PF15906.5 PSC71100.1 - 0.053 13.6 0.0 0.16 12.1 0.0 1.8 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein His_Phos_1 PF00300.22 PSC71101.1 - 6.8e-31 107.5 0.0 9.7e-31 107.0 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) His_Phos_2 PF00328.22 PSC71101.1 - 9.7e-06 25.2 0.0 1.3e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) zf-HC5HC2H_2 PF13832.6 PSC71102.1 - 1.4e-17 63.9 0.1 1.4e-17 63.9 0.1 3.1 3 0 0 3 3 3 1 PHD-zinc-finger like domain PHD_2 PF13831.6 PSC71102.1 - 1.2e-11 43.9 3.8 1.2e-11 43.9 3.8 2.6 2 0 0 2 2 2 1 PHD-finger zf-HC5HC2H PF13771.6 PSC71102.1 - 6e-11 42.5 0.0 6e-11 42.5 0.0 3.4 4 0 0 4 4 4 1 PHD-like zinc-binding domain PHD PF00628.29 PSC71102.1 - 7.8e-11 41.7 19.4 1.9e-10 40.5 5.5 3.1 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.22 PSC71102.1 - 1.5e-05 24.8 0.1 1.5e-05 24.8 0.1 2.7 3 0 0 3 3 3 1 Phorbol esters/diacylglycerol binding domain (C1 domain) Ada3 PF10198.9 PSC71102.1 - 0.00039 20.6 0.6 0.00039 20.6 0.6 4.4 3 0 0 3 3 3 1 Histone acetyltransferases subunit 3 FYVE_2 PF02318.16 PSC71102.1 - 0.0019 18.4 0.3 0.0019 18.4 0.3 3.0 3 0 0 3 3 3 1 FYVE-type zinc finger C1_2 PF03107.16 PSC71102.1 - 0.01 16.2 5.4 0.22 11.9 0.7 2.6 2 0 0 2 2 2 0 C1 domain Prok-RING_1 PF14446.6 PSC71102.1 - 0.3 11.1 10.4 0.096 12.6 3.4 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 SNF2_N PF00176.23 PSC71103.1 - 5.7e-62 209.5 0.0 1.3e-61 208.3 0.0 1.5 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC71103.1 - 8.8e-19 67.9 0.0 1.8e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC71103.1 - 8.6e-07 29.1 0.0 3e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 PSC71103.1 - 0.00094 18.2 0.0 0.0022 17.0 0.0 1.5 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 ERCC3_RAD25_C PF16203.5 PSC71103.1 - 0.067 12.4 0.0 0.16 11.2 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase Histone_H2A_C PF16211.5 PSC71104.1 - 6e-20 70.7 1.8 1.2e-19 69.7 1.8 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 PSC71104.1 - 1.8e-15 57.4 0.0 2.3e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC71104.1 - 1.5e-05 25.1 0.0 2.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Glyco_hydro_47 PF01532.20 PSC71105.1 - 6.7e-128 427.4 0.0 7.9e-128 427.2 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Nucleotid_trans PF03407.16 PSC71106.1 - 6.2e-09 36.1 0.0 1e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Efg1 PF10153.9 PSC71107.1 - 1.3e-29 102.8 7.9 3.3e-29 101.6 7.9 1.7 1 0 0 1 1 1 1 rRNA-processing protein Efg1 DUF3769 PF12600.8 PSC71107.1 - 2.3e-06 26.8 0.0 0.0032 16.4 0.0 2.5 3 0 0 3 3 3 2 Protein of unknown function (DUF3769) SUV3_C PF12513.8 PSC71108.1 - 3.9e-13 49.1 0.0 1.1e-12 47.6 0.0 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 PSC71108.1 - 2.3e-09 37.0 0.3 5.2e-09 35.8 0.3 1.7 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 PSC71108.1 - 6.3e-09 36.2 0.0 1e-08 35.5 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RepA_C PF04796.12 PSC71108.1 - 0.11 12.6 0.0 0.19 11.8 0.0 1.3 1 0 0 1 1 1 0 Plasmid encoded RepA protein TFIIB PF00382.19 PSC71109.1 - 1.2e-17 63.7 0.6 3.8e-12 46.1 0.9 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 PSC71109.1 - 1.2e-15 56.7 0.8 1.2e-15 56.7 0.8 1.8 2 0 0 2 2 2 1 TFIIB zinc-binding Ribosomal_S27e PF01667.17 PSC71109.1 - 0.0067 16.1 0.4 0.016 14.9 0.4 1.6 1 0 0 1 1 1 1 Ribosomal protein S27 zf-RRN7 PF11781.8 PSC71109.1 - 0.016 14.8 1.7 0.016 14.8 1.7 2.6 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF4047 PF13256.6 PSC71109.1 - 0.032 14.4 0.0 0.065 13.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) DUF2318 PF10080.9 PSC71109.1 - 0.036 14.2 0.7 0.73 10.0 0.3 2.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2318) Prim_Zn_Ribbon PF08273.12 PSC71109.1 - 0.042 14.1 0.4 0.042 14.1 0.4 3.1 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase A2L_zn_ribbon PF08792.10 PSC71109.1 - 0.24 11.2 1.1 24 4.8 0.0 2.6 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-ribbon_3 PF13248.6 PSC71109.1 - 9.7 5.8 9.1 9.9 5.7 4.2 2.7 2 1 0 2 2 2 0 zinc-ribbon domain WD40 PF00400.32 PSC71110.1 - 1.6e-18 66.7 0.0 0.017 16.0 0.0 6.6 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC71110.1 - 1.8e-15 57.0 0.4 0.00042 20.6 0.0 5.8 1 1 5 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Arm PF00514.23 PSC71110.1 - 6.4e-11 41.9 11.8 0.085 12.9 0.7 4.6 4 0 0 4 4 4 4 Armadillo/beta-catenin-like repeat IKI3 PF04762.12 PSC71110.1 - 0.0016 16.5 0.0 0.031 12.3 0.0 2.2 1 1 1 2 2 2 2 IKI3 family HEAT PF02985.22 PSC71110.1 - 1.5 9.3 6.7 37 5.0 0.4 4.0 3 0 0 3 3 3 0 HEAT repeat PUL PF08324.11 PSC71110.1 - 4.1 6.5 7.6 0.49 9.6 0.1 2.4 1 1 1 3 3 3 0 PUL domain DUF92 PF01940.16 PSC71111.1 - 1e-66 224.7 13.6 1.3e-66 224.4 13.6 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 Ysc84 PF04366.12 PSC71112.1 - 1.1e-34 118.9 1.2 2.1e-34 118.0 1.2 1.4 1 0 0 1 1 1 1 Las17-binding protein actin regulator FYVE PF01363.21 PSC71112.1 - 3.4e-17 62.3 3.8 5.6e-17 61.6 3.8 1.3 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 PSC71112.1 - 0.18 12.0 3.6 0.28 11.4 3.6 1.2 1 0 0 1 1 1 0 FYVE-type zinc finger zf-CW PF07496.15 PSC71113.1 - 1.4e-12 47.4 7.5 2.3e-12 46.7 7.5 1.4 1 0 0 1 1 1 1 CW-type Zinc Finger HEPN_SAV_6107 PF18726.1 PSC71113.1 - 1.2 9.7 13.7 0.065 13.7 5.4 3.0 2 1 1 3 3 3 0 SAV_6107-like HEPN ABC1 PF03109.16 PSC71114.1 - 1.4e-26 93.0 0.0 2.2e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 ABC1 family DUF3700 PF12481.8 PSC71115.1 - 2.4e-12 46.8 0.0 7.6e-10 38.6 0.0 2.2 2 0 0 2 2 2 2 Aluminium induced protein GATase_7 PF13537.6 PSC71115.1 - 4.4e-11 42.8 0.0 2.6e-10 40.3 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 PSC71115.1 - 1.6e-05 25.1 0.0 5.2e-05 23.4 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain Peptidase_M11 PF05548.11 PSC71116.1 - 5.2e-70 236.1 10.7 8.4e-23 81.0 0.4 3.5 3 0 0 3 3 3 3 Gametolysin peptidase M11 Reprolysin_4 PF13583.6 PSC71116.1 - 9.6e-09 35.2 5.0 0.13 11.9 0.1 4.3 3 0 0 3 3 3 3 Metallo-peptidase family M12B Reprolysin-like Microcin PF03526.13 PSC71116.1 - 0.00011 21.9 7.1 2.7 7.9 0.2 3.7 3 0 0 3 3 3 3 Colicin E1 (microcin) immunity protein Reprolysin_5 PF13688.6 PSC71116.1 - 0.0003 21.0 5.4 4.5 7.4 0.2 3.7 3 0 0 3 3 3 3 Metallo-peptidase family M12 Cu-binding_MopE PF11617.8 PSC71116.1 - 0.00048 20.2 12.1 2.2 8.5 0.5 3.9 3 0 0 3 3 3 3 Putative metal-binding motif TH1 PF04858.13 PSC71116.1 - 0.00099 17.9 7.9 1.6 7.3 0.2 3.1 3 0 0 3 3 3 3 TH1 protein DUF2960 PF11173.8 PSC71116.1 - 0.008 16.6 3.2 31 5.1 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2960) BCMA-Tall_bind PF09257.10 PSC71116.1 - 0.013 15.6 10.6 4.2 7.5 0.4 3.6 3 0 0 3 3 3 0 BCMA, TALL-1 binding RAP80_UIM PF18282.1 PSC71116.1 - 0.023 14.5 1.4 49 3.8 0.0 3.3 3 0 0 3 3 3 0 RAP80 N-terminal ubiquitin interaction motif Peptidase_M66 PF10462.9 PSC71116.1 - 0.028 13.4 9.6 5 6.0 0.2 3.3 3 0 0 3 3 3 0 Peptidase M66 LCCL PF03815.19 PSC71116.1 - 0.048 13.8 0.1 6.9 6.9 0.1 2.7 2 0 0 2 2 2 0 LCCL domain Peptidase_M32 PF02074.15 PSC71116.1 - 0.44 9.3 1.0 73 1.9 0.0 2.9 3 0 0 3 3 3 0 Carboxypeptidase Taq (M32) metallopeptidase Pentapeptide_4 PF13599.6 PSC71116.1 - 0.55 10.4 12.3 18 5.6 0.5 3.4 3 0 0 3 3 3 0 Pentapeptide repeats (9 copies) Reprolysin_3 PF13582.6 PSC71116.1 - 0.67 10.5 12.1 25 5.4 0.5 4.2 3 3 0 3 3 3 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 PSC71116.1 - 0.89 8.1 3.9 41 2.6 0.1 3.0 3 0 0 3 3 3 0 Putative peptidase family Peptidase_M64 PF09471.10 PSC71116.1 - 1.8 8.0 4.3 58 3.1 0.1 3.0 3 0 0 3 3 3 0 IgA Peptidase M64 Calmodulin_bind PF07887.11 PSC71117.1 - 3.2e-18 66.1 0.0 3.8e-17 62.5 0.0 2.4 1 1 0 1 1 1 1 Calmodulin binding protein-like MCM PF00493.23 PSC71118.1 - 1.5e-102 341.4 0.0 4.1e-102 340.0 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 PSC71118.1 - 1.1e-24 86.7 0.0 2e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PSC71118.1 - 5.5e-22 78.0 4.6 8.2e-22 77.4 1.7 2.5 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 PSC71118.1 - 1.5e-09 38.4 0.1 3.6e-09 37.2 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain AAA_5 PF07728.14 PSC71118.1 - 5.4e-07 29.7 0.0 1.6e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 PSC71118.1 - 3.8e-06 26.4 0.2 0.00013 21.5 0.0 2.8 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 PSC71118.1 - 0.00016 21.6 0.1 0.00073 19.4 0.1 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PIG-S PF10510.9 PSC71118.1 - 0.026 13.3 0.0 0.045 12.6 0.0 1.4 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein AAA_lid_2 PF17863.1 PSC71118.1 - 0.03 14.2 0.2 0.11 12.3 0.2 2.1 1 0 0 1 1 1 0 AAA lid domain AAA_16 PF13191.6 PSC71118.1 - 0.23 11.8 2.7 2.7 8.3 0.0 3.3 3 1 0 4 4 4 0 AAA ATPase domain Mg_chelatase_C PF13335.6 PSC71118.1 - 1.1 9.9 4.6 0.7 10.6 0.8 2.8 3 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI C-terminal ANAPC_CDC26 PF10471.9 PSC71118.1 - 5.6 7.9 6.2 52 4.8 2.0 3.3 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 WD40 PF00400.32 PSC71119.1 - 1.2e-16 60.8 3.8 0.0025 18.6 0.0 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC71119.1 - 1.7e-06 28.2 0.0 0.75 10.1 0.0 4.1 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PSC71119.1 - 1.9e-05 24.1 0.0 4.8e-05 22.8 0.0 1.5 1 1 0 1 1 1 1 WD40-like domain eIF2A PF08662.11 PSC71119.1 - 0.00032 20.6 0.3 0.013 15.4 0.1 2.6 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 PSC71119.1 - 0.0075 15.0 0.4 0.22 10.1 0.1 2.2 1 1 1 2 2 2 2 Nucleoporin Nup120/160 NUP214 PF16755.5 PSC71119.1 - 0.044 13.0 0.0 0.086 12.1 0.0 1.5 1 1 0 1 1 1 0 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 B3 PF02362.21 PSC71120.1 - 3.1e-10 39.8 0.0 4.6e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 B3 DNA binding domain SUIM_assoc PF16619.5 PSC71120.1 - 0.031 14.3 0.2 0.065 13.3 0.2 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 APC_N_CC PF16689.5 PSC71120.1 - 0.083 13.0 0.1 0.16 12.0 0.1 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of APC, dimerisation domain TAL_FSA PF00923.19 PSC71121.1 - 1.4e-29 103.4 0.0 5.6e-24 85.0 0.0 2.1 1 1 1 2 2 2 2 Transaldolase/Fructose-6-phosphate aldolase Phage-MuB_C PF09077.11 PSC71121.1 - 0.048 13.5 1.1 0.092 12.6 0.3 1.9 2 0 0 2 2 2 0 Mu B transposition protein, C terminal Voltage_CLC PF00654.20 PSC71122.1 - 5.7e-72 242.9 25.5 5.7e-72 242.9 25.5 3.0 2 1 1 3 3 3 1 Voltage gated chloride channel CBS PF00571.28 PSC71122.1 - 3.3e-05 24.2 0.1 0.00077 19.9 0.0 2.6 3 0 0 3 3 3 1 CBS domain CDC45 PF02724.14 PSC71123.1 - 0.7 8.1 14.4 1.1 7.5 14.4 1.2 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.17 PSC71123.1 - 4.5 7.4 6.0 8 6.6 6.0 1.3 1 0 0 1 1 1 0 DDHD domain Glyco_transf_22 PF03901.17 PSC71124.1 - 9.9e-47 160.1 4.4 1.4e-46 159.6 4.4 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family ARID PF01388.21 PSC71124.1 - 6.2e-08 33.2 0.0 1.1e-07 32.4 0.0 1.4 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain LBR_tudor PF09465.10 PSC71124.1 - 0.0015 18.2 0.0 0.0039 17.0 0.0 1.6 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain ADH_N PF08240.12 PSC71125.1 - 3.1e-25 88.2 2.3 5.2e-25 87.4 2.3 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PSC71125.1 - 7e-24 84.3 0.0 1.2e-23 83.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 PSC71125.1 - 4.6e-07 29.5 0.0 6.6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus ADH_zinc_N_2 PF13602.6 PSC71125.1 - 6.3e-07 30.5 0.0 1.1e-06 29.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 PSC71125.1 - 0.017 14.4 3.5 0.03 13.6 3.5 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Methyltransf_25 PF13649.6 PSC71125.1 - 0.019 15.7 0.1 0.076 13.7 0.1 2.1 1 1 0 1 1 1 0 Methyltransferase domain ADH_N_assoc PF13823.6 PSC71125.1 - 0.083 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-associated Methyltransf_11 PF08241.12 PSC71125.1 - 0.11 13.2 0.1 0.99 10.1 0.1 2.3 1 1 0 1 1 1 0 Methyltransferase domain Orbi_VP6 PF01516.16 PSC71126.1 - 0.76 9.2 2.5 1.2 8.6 2.5 1.2 1 0 0 1 1 1 0 Orbivirus helicase VP6 TUSC2 PF15000.6 PSC71127.1 - 0.00066 19.9 0.2 0.0047 17.2 0.0 2.2 2 1 0 2 2 2 1 Tumour suppressor candidate 2 DUF3103 PF11301.8 PSC71127.1 - 0.079 11.7 0.1 0.14 11.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3103) Neurokinin_B PF03823.14 PSC71127.1 - 0.81 9.8 4.4 0.44 10.6 1.9 1.9 1 1 1 2 2 2 0 Neurokinin B PALP PF00291.25 PSC71128.1 - 1.8e-73 247.5 8.3 2.1e-73 247.3 8.3 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DFP PF04127.15 PSC71128.1 - 0.1 12.4 1.9 0.23 11.3 0.4 2.0 2 0 0 2 2 2 0 DNA / pantothenate metabolism flavoprotein PI3_PI4_kinase PF00454.27 PSC71129.1 - 1.7e-50 172.2 0.0 2.4e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 PSC71129.1 - 7.3e-11 41.7 0.1 1.8e-10 40.5 0.1 1.6 1 0 0 1 1 1 1 FATC domain TAN PF11640.8 PSC71129.1 - 6.5e-06 26.4 0.0 4.8e-05 23.5 0.0 2.4 2 0 0 2 2 2 1 Telomere-length maintenance and DNA damage repair FAT PF02259.23 PSC71129.1 - 2.5e-05 23.7 1.1 0.00015 21.1 1.1 2.2 1 1 0 1 1 1 1 FAT domain PCRF PF03462.18 PSC71130.1 - 0.08 12.8 2.1 0.14 12.0 2.1 1.3 1 0 0 1 1 1 0 PCRF domain DUF1959 PF09218.10 PSC71130.1 - 0.3 11.2 1.7 29 4.8 0.4 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF1959) Com_YlbF PF06133.11 PSC71130.1 - 0.35 11.5 5.4 0.22 12.1 3.7 1.5 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA LemA PF04011.12 PSC71130.1 - 1.3 8.8 5.4 3.2 7.6 5.4 1.8 1 1 0 1 1 1 0 LemA family L_biotic_typeA PF04604.13 PSC71130.1 - 2.3 8.2 0.0 2.3 8.2 0.0 2.8 3 0 0 3 3 3 0 Type-A lantibiotic CobN-Mg_chel PF02514.16 PSC71131.1 - 4.2e-298 991.7 0.0 5.7e-298 991.3 0.0 1.2 1 0 0 1 1 1 1 CobN/Magnesium Chelatase OMPdecase PF00215.24 PSC71131.1 - 2.3e-74 249.8 0.2 7.5e-74 248.1 0.1 1.9 2 0 0 2 2 2 1 Orotidine 5'-phosphate decarboxylase / HUMPS family DUF3479 PF11965.8 PSC71131.1 - 9.9e-51 172.0 0.0 3.3e-50 170.3 0.0 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3479) Pribosyltran PF00156.27 PSC71131.1 - 1.2e-08 34.6 0.0 2.6e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl transferase domain SlyX PF04102.12 PSC71131.1 - 0.024 15.2 0.1 0.17 12.5 0.1 2.5 2 0 0 2 2 2 0 SlyX TolA_bind_tri PF16331.5 PSC71131.1 - 0.1 12.7 0.3 0.56 10.3 0.3 2.3 1 0 0 1 1 1 0 TolA binding protein trimerisation T4SS PF07996.11 PSC71131.1 - 0.14 12.6 3.1 0.22 11.9 1.5 2.2 2 0 0 2 2 2 0 Type IV secretion system proteins DUF3138 PF11336.8 PSC71131.1 - 6.7 5.2 15.6 0.055 12.1 7.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Endosulfine PF04667.17 PSC71132.1 - 9.1e-11 41.7 0.1 1.2e-10 41.4 0.1 1.2 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region EF-hand_1 PF00036.32 PSC71133.1 - 1.5e-13 49.2 0.8 9.1e-06 24.9 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 PSC71133.1 - 1.2e-10 41.7 0.0 2.3e-10 40.7 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PSC71133.1 - 5.5e-10 38.4 0.1 3.1e-05 23.6 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PSC71133.1 - 8.8e-10 37.6 0.4 1e-05 24.8 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PSC71133.1 - 1.7e-07 31.0 0.1 0.0011 18.7 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair Nore1-SARAH PF16517.5 PSC71133.1 - 0.026 14.4 0.2 0.026 14.4 0.2 1.8 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain EF-hand_4 PF12763.7 PSC71133.1 - 0.18 11.7 0.2 5.5 7.0 0.1 2.2 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand RBM39linker PF15519.6 PSC71133.1 - 4.9 8.3 7.0 0.55 11.3 0.6 2.6 2 1 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein EF-hand_1 PF00036.32 PSC71134.1 - 1.4e-13 49.3 0.8 8.8e-06 24.9 0.1 2.4 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 PSC71134.1 - 4.3e-11 43.1 0.1 8.2e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PSC71134.1 - 5.4e-10 38.4 0.1 3e-05 23.6 0.1 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PSC71134.1 - 8.1e-10 37.7 0.4 9.7e-06 24.9 0.1 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PSC71134.1 - 1.9e-08 34.0 1.1 3.6e-07 29.9 0.2 2.5 1 1 1 2 2 2 2 EF-hand domain pair Nore1-SARAH PF16517.5 PSC71134.1 - 0.025 14.5 0.2 0.025 14.5 0.2 1.8 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain EF-hand_4 PF12763.7 PSC71134.1 - 0.13 12.3 0.3 3 7.8 0.1 2.2 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand RBM39linker PF15519.6 PSC71134.1 - 5.2 8.2 7.1 0.53 11.4 0.6 2.5 2 1 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein Histone PF00125.24 PSC71135.1 - 2.4e-53 180.0 3.1 2.7e-53 179.8 3.1 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.6 PSC71135.1 - 0.00013 22.2 0.0 0.00021 21.6 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 PSC71135.1 - 0.00018 22.1 2.1 0.00021 21.9 2.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 PSC71135.1 - 0.0002 21.4 0.7 0.00029 20.9 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 PSC71135.1 - 0.0027 18.0 0.1 0.0056 16.9 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PSC71135.1 - 0.012 15.6 0.2 0.028 14.5 0.0 1.6 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit DUF4840 PF16128.5 PSC71135.1 - 0.19 11.8 0.0 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4840) TPR_2 PF07719.17 PSC71136.1 - 3.1e-13 48.7 11.7 6.9e-05 22.7 1.8 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 PSC71136.1 - 9.5e-13 47.4 8.7 0.00033 20.3 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.6 PSC71136.1 - 7.6e-06 26.5 22.2 0.024 15.3 1.6 3.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 PSC71136.1 - 9e-06 25.3 6.7 0.0029 17.3 2.6 3.0 1 1 2 3 3 3 2 TPR repeat TPR_12 PF13424.6 PSC71136.1 - 2.3e-05 24.6 13.6 0.00064 20.0 3.6 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 PSC71136.1 - 2.6e-05 24.1 5.6 0.75 10.2 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 PSC71136.1 - 0.00075 19.7 7.9 0.0078 16.5 0.5 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PSC71136.1 - 0.0014 19.2 13.2 0.037 14.8 1.8 4.4 1 1 3 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 PSC71136.1 - 0.009 16.0 8.7 0.088 12.9 0.1 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 PSC71136.1 - 0.0095 16.4 2.4 0.0095 16.4 2.4 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 PSC71136.1 - 0.013 15.7 5.3 0.067 13.4 0.7 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TSSC4 PF15264.6 PSC71136.1 - 0.015 15.5 0.5 0.044 14.1 0.0 2.1 2 0 0 2 2 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 DUF3856 PF12968.7 PSC71136.1 - 0.051 13.6 5.6 0.25 11.4 3.1 3.0 2 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) MIT PF04212.18 PSC71136.1 - 0.15 12.1 5.2 0.31 11.2 0.3 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain DUF3018 PF11455.8 PSC71136.1 - 0.23 11.4 1.6 1.7 8.7 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3018) TPR_6 PF13174.6 PSC71136.1 - 0.33 11.7 7.6 4 8.3 0.7 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 PSC71136.1 - 0.46 10.9 5.5 39 4.7 5.5 2.6 1 1 0 1 1 1 0 Alkyl sulfatase dimerisation TPR_20 PF14561.6 PSC71136.1 - 0.97 9.8 7.9 0.23 11.8 1.2 3.1 2 1 2 4 4 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 PSC71136.1 - 2 8.4 12.5 6 6.9 0.6 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF72 PF01904.18 PSC71137.1 - 5.6e-48 163.9 0.1 7.6e-48 163.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF72 V-ATPase_C PF03223.15 PSC71138.1 - 1.4e-113 380.0 0.0 1.7e-113 379.8 0.0 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DUF641 PF04859.12 PSC71138.1 - 0.12 12.7 0.3 0.29 11.5 0.3 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) BACK PF07707.15 PSC71139.1 - 2.3e-05 24.4 0.0 5.4e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 BTB And C-terminal Kelch ATP-synt_C PF00137.21 PSC71139.1 - 0.28 11.5 1.7 0.6 10.5 1.7 1.4 1 0 0 1 1 1 0 ATP synthase subunit C Formyl_trans_N PF00551.19 PSC71140.1 - 9.3e-39 133.0 0.0 1.4e-38 132.4 0.0 1.2 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 PSC71140.1 - 2.1e-18 66.4 0.0 4.9e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Formyl transferase, C-terminal domain IMUP PF15761.5 PSC71140.1 - 0.11 13.1 14.7 2.5 8.8 0.6 2.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein Peptidase_C13 PF01650.18 PSC71141.1 - 1.8e-92 309.5 0.0 2.6e-92 309.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family RelB PF04221.12 PSC71141.1 - 0.085 12.8 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 RelB antitoxin Peptidase_C14 PF00656.22 PSC71141.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Caspase domain MBOAT PF03062.19 PSC71143.1 - 3.6e-29 102.2 20.9 6.5e-29 101.4 20.9 1.3 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family PH PF00169.29 PSC71143.1 - 1.4e-07 32.0 0.0 3e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 PH domain MBOAT_2 PF13813.6 PSC71143.1 - 0.008 16.4 5.3 0.008 16.4 5.3 2.0 1 1 1 2 2 2 1 Membrane bound O-acyl transferase family PH_11 PF15413.6 PSC71143.1 - 0.23 11.9 1.0 1.4 9.4 0.1 2.7 2 1 0 2 2 2 0 Pleckstrin homology domain SAM_1 PF00536.30 PSC71144.1 - 3e-12 46.8 0.0 8.5e-12 45.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PSC71144.1 - 6.1e-10 39.1 0.0 1.4e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) zf-C2H2_12 PF18658.1 PSC71144.1 - 0.85 9.2 3.4 18 5.0 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger C2H2-type Galactosyl_T PF01762.21 PSC71145.1 - 2.6e-28 99.2 0.0 3.5e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Glyco_tranf_2_4 PF13704.6 PSC71145.1 - 0.043 14.3 0.0 0.099 13.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 DUF1126 PF06565.12 PSC71146.1 - 1.2e-81 269.3 0.0 1.8e-26 92.0 0.0 3.2 3 0 0 3 3 3 3 DUF1126 PH-like domain GCV_H PF01597.19 PSC71146.1 - 1.1e-42 144.8 0.1 1.8e-42 144.1 0.1 1.3 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 PSC71146.1 - 0.11 12.4 0.1 0.25 11.2 0.1 1.6 1 0 0 1 1 1 0 Biotin-requiring enzyme zf-HC5HC2H_2 PF13832.6 PSC71147.1 - 1.8e-28 98.9 4.6 1.8e-28 98.9 4.6 2.8 3 0 0 3 3 3 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 PSC71147.1 - 1.7e-20 73.1 0.3 1.7e-20 73.1 0.3 3.4 3 1 1 4 4 4 1 PHD-like zinc-binding domain SAND PF01342.21 PSC71147.1 - 9.8e-20 70.1 2.9 4.5e-07 29.5 0.3 4.1 4 1 0 4 4 4 3 SAND domain SET PF00856.28 PSC71147.1 - 3.7e-12 46.9 3.3 1.7e-11 44.8 0.0 3.3 3 1 0 3 3 3 1 SET domain PHD_2 PF13831.6 PSC71147.1 - 8.6e-11 41.2 5.9 3e-10 39.5 1.1 2.8 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 PSC71147.1 - 2.8e-08 33.5 15.4 4.4e-07 29.7 8.8 3.5 4 0 0 4 4 4 2 PHD-finger HMG_box PF00505.19 PSC71147.1 - 1.5e-05 25.3 0.0 4.6e-05 23.7 0.0 1.9 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PSC71147.1 - 0.0013 19.3 0.1 0.0013 19.3 0.1 2.1 2 0 0 2 2 1 1 HMG-box domain C1_1 PF00130.22 PSC71147.1 - 0.0014 18.5 1.7 0.0014 18.5 1.7 3.0 3 0 0 3 3 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 PSC71147.1 - 0.0056 16.6 20.6 0.027 14.4 1.1 3.0 3 0 0 3 3 3 2 Prokaryotic RING finger family 1 HMG_box_5 PF14887.6 PSC71147.1 - 0.11 12.5 0.9 0.45 10.5 0.1 2.5 2 0 0 2 2 2 0 HMG (high mobility group) box 5 GSH_synth_ATP PF03917.17 PSC71148.1 - 7.6e-111 370.5 0.0 1.1e-110 369.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 PSC71148.1 - 1.5e-30 105.7 0.0 2.8e-30 104.8 0.0 1.5 1 0 0 1 1 1 1 Eukaryotic glutathione synthase Adaptin_N PF01602.20 PSC71149.1 - 1.2e-123 413.5 5.2 1.4e-123 413.2 5.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region COP-gamma_platf PF08752.10 PSC71149.1 - 1.8e-51 174.2 0.5 4e-51 173.1 0.2 1.8 2 0 0 2 2 2 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 PSC71149.1 - 7.1e-35 119.6 0.0 1.5e-34 118.6 0.0 1.6 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 PSC71149.1 - 2.4e-17 63.1 7.0 4.9e-08 33.2 0.1 6.4 4 2 2 6 6 6 3 HEAT repeats Cnd1 PF12717.7 PSC71149.1 - 8.1e-11 42.2 6.9 0.00017 21.6 0.5 4.1 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PSC71149.1 - 2.5e-06 27.3 5.9 8.3 7.0 0.0 7.1 7 0 0 7 7 7 2 HEAT repeat HEAT_PBS PF03130.16 PSC71149.1 - 0.00057 20.3 1.3 2.6 9.0 0.3 5.5 4 0 0 4 4 4 1 PBS lyase HEAT-like repeat Arm PF00514.23 PSC71149.1 - 0.014 15.4 0.0 2.6 8.2 0.0 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat AbiJ_NTD5 PF18865.1 PSC71149.1 - 0.14 12.0 0.3 0.34 10.7 0.1 1.8 2 0 0 2 2 2 0 AbiJ N-terminal domain 5 HEAT_EZ PF13513.6 PSC71149.1 - 0.34 11.5 11.1 0.64 10.6 0.2 4.8 5 0 0 5 5 4 0 HEAT-like repeat FANCI_S2 PF14676.6 PSC71149.1 - 2.1 8.6 6.4 0.56 10.5 0.1 3.2 4 0 0 4 4 4 0 FANCI solenoid 2 AA_permease_2 PF13520.6 PSC71150.1 - 6.1e-44 150.5 34.5 8.2e-44 150.1 34.5 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 PSC71150.1 - 7.8e-31 107.2 31.2 1.1e-30 106.6 31.2 1.2 1 0 0 1 1 1 1 Amino acid permease Spt5-NGN PF03439.13 PSC71150.1 - 1.8e-24 85.5 0.0 3.7e-24 84.4 0.0 1.6 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section AA_permease_C PF13906.6 PSC71150.1 - 8e-13 48.3 2.9 2.5e-12 46.7 2.9 1.9 1 0 0 1 1 1 1 C-terminus of AA_permease KOW PF00467.29 PSC71150.1 - 6.3e-11 41.8 34.4 0.0035 17.2 1.1 6.9 7 0 0 7 7 7 6 KOW motif Spt5_N PF11942.8 PSC71150.1 - 6.3e-11 43.1 10.3 6.3e-11 43.1 10.3 2.9 2 1 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal Spore_permease PF03845.13 PSC71150.1 - 0.0077 15.1 8.2 0.014 14.2 8.2 1.3 1 1 0 1 1 1 1 Spore germination protein SMC_hinge PF06470.13 PSC71150.1 - 0.0086 16.4 0.0 0.058 13.7 0.0 2.3 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain SET PF00856.28 PSC71151.1 - 2.1e-07 31.5 1.9 2.6e-06 27.9 0.0 3.4 4 1 0 4 4 4 1 SET domain Tyr-DNA_phospho PF06087.12 PSC71152.1 - 9.4e-75 252.1 0.0 1.1e-74 251.9 0.0 1.0 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase Chloroa_b-bind PF00504.21 PSC71153.1 - 4.8e-43 147.5 0.0 6.3e-43 147.1 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Snf7 PF03357.21 PSC71154.1 - 1.7e-28 99.4 18.7 1.7e-28 99.4 18.7 1.6 1 1 1 2 2 2 1 Snf7 Tox-SHH PF15652.6 PSC71154.1 - 0.086 13.8 6.5 0.3 12.0 0.8 2.9 2 1 1 3 3 3 0 HNH/Endo VII superfamily toxin with a SHH signature Peptidase_M32 PF02074.15 PSC71154.1 - 0.93 8.2 10.4 0.033 13.0 2.0 1.9 1 1 0 2 2 2 0 Carboxypeptidase Taq (M32) metallopeptidase FAA_hydrolase_N PF09298.11 PSC71154.1 - 3.3 7.9 5.7 1 9.6 0.8 2.4 1 1 2 3 3 3 0 Fumarylacetoacetase N-terminal Fe_hyd_lg_C PF02906.14 PSC71155.1 - 2.8e-84 282.6 0.0 2.3e-83 279.6 0.0 2.0 1 1 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 PSC71155.1 - 5.1e-24 84.1 0.1 9.4e-24 83.3 0.1 1.5 1 0 0 1 1 1 1 Iron hydrogenase small subunit NADH-G_4Fe-4S_3 PF10588.9 PSC71155.1 - 2.6e-13 49.3 0.2 2.6e-13 49.3 0.2 2.0 3 0 0 3 3 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer4 PF00037.27 PSC71155.1 - 2.3e-11 43.0 20.5 3.7e-07 29.7 3.6 3.6 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_8 PF13183.6 PSC71155.1 - 1.3e-08 35.1 7.3 1.3e-08 35.1 7.3 2.3 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 PSC71155.1 - 3.2e-08 33.5 21.0 2.5e-07 30.7 10.3 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_7 PF12838.7 PSC71155.1 - 4.5e-08 33.5 20.0 1.3e-07 32.1 10.5 3.3 3 1 1 4 4 3 2 4Fe-4S dicluster domain Fer4_21 PF14697.6 PSC71155.1 - 8.3e-08 32.3 7.5 8.3e-08 32.3 7.5 2.0 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_9 PF13187.6 PSC71155.1 - 1.2e-06 28.6 9.7 1.2e-06 28.6 9.7 3.1 2 1 2 4 4 4 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 PSC71155.1 - 6.2e-06 26.0 19.6 0.00032 20.6 3.1 3.6 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_6 PF12837.7 PSC71155.1 - 1.2e-05 25.1 13.5 7.3e-05 22.7 3.3 3.3 4 0 0 4 4 2 2 4Fe-4S binding domain Fer4_16 PF13484.6 PSC71155.1 - 3.3e-05 24.7 13.1 0.00013 22.8 2.1 3.3 3 0 0 3 3 3 1 4Fe-4S double cluster binding domain Fer4_17 PF13534.6 PSC71155.1 - 0.00032 21.2 9.6 0.00032 21.2 9.6 2.6 1 1 1 2 2 2 1 4Fe-4S dicluster domain Fer4_22 PF17179.4 PSC71155.1 - 0.002 19.0 11.4 0.028 15.3 0.4 2.9 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_4 PF12800.7 PSC71155.1 - 0.0052 17.2 23.3 0.0075 16.7 3.3 3.7 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_18 PF13746.6 PSC71155.1 - 0.19 11.9 14.4 0.59 10.3 2.4 2.9 2 1 1 3 3 3 0 4Fe-4S dicluster domain Fer4_15 PF13459.6 PSC71155.1 - 0.34 11.7 16.1 0.41 11.4 0.5 3.7 3 1 0 3 3 3 0 4Fe-4S single cluster domain Fer4_13 PF13370.6 PSC71155.1 - 0.72 10.4 15.6 1.3 9.6 3.5 3.0 3 0 0 3 3 2 0 4Fe-4S single cluster domain of Ferredoxin I HORMA PF02301.18 PSC71156.1 - 1.9e-51 174.7 0.0 2.6e-51 174.2 0.0 1.2 1 0 0 1 1 1 1 HORMA domain Glyco_hydro_9 PF00759.19 PSC71157.1 - 1.2e-75 255.6 5.7 1.8e-75 255.0 5.7 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_trans_2_3 PF13632.6 PSC71157.1 - 1e-16 61.4 0.4 1e-16 61.4 0.4 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 PSC71157.1 - 9e-14 51.9 0.0 3.4e-13 50.0 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 PSC71157.1 - 2.4e-10 40.5 0.0 4.3e-10 39.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Cellulose_synt PF03552.14 PSC71157.1 - 1.8e-07 30.1 4.3 1.1e-06 27.5 0.8 2.1 2 0 0 2 2 2 2 Cellulose synthase Glyco_transf_21 PF13506.6 PSC71157.1 - 0.012 15.1 0.0 0.054 13.0 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferase family 21 Histone PF00125.24 PSC71158.1 - 1e-15 58.3 0.0 1.2e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC71158.1 - 0.0077 16.5 0.1 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DnaJ PF00226.31 PSC71158.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain RP-C PF03428.13 PSC71158.1 - 0.06 13.0 0.4 3.4 7.3 0.0 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain TFIID_20kDa PF03847.13 PSC71158.1 - 0.2 12.2 0.0 0.33 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A DUF190 PF02641.15 PSC71159.1 - 0.091 13.1 0.0 0.13 12.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized ACR, COG1993 DNA_pol_A_exo1 PF01612.20 PSC71160.1 - 1.8e-14 53.8 0.0 3e-13 49.9 0.0 2.6 1 1 0 1 1 1 1 3'-5' exonuclease HTH_40 PF14493.6 PSC71160.1 - 3.9e-06 27.2 0.0 3.5e-05 24.2 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain Mlo PF03094.15 PSC71161.1 - 4.7e-64 216.5 3.6 4.3e-35 121.0 0.3 3.1 3 0 0 3 3 3 3 Mlo family Alpha-amyl_C2 PF07821.12 PSC71161.1 - 1.2e-20 73.5 0.9 2.2e-20 72.6 0.2 1.9 2 0 0 2 2 2 1 Alpha-amylase C-terminal beta-sheet domain Alpha-amylase PF00128.24 PSC71161.1 - 1.3e-16 61.2 0.0 5.6e-16 59.0 0.0 2.0 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 PSC71161.1 - 0.081 11.1 0.0 0.12 10.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 70 DoxX PF07681.12 PSC71161.1 - 2.3 8.9 7.5 0.19 12.4 1.2 2.4 2 0 0 2 2 2 0 DoxX Phage_lysis PF03245.13 PSC71161.1 - 2.4 8.3 6.6 1.5 8.9 3.2 2.2 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein Adeno_PIX PF03955.14 PSC71161.1 - 8.5 6.6 7.9 7.5 6.8 4.4 2.6 2 0 0 2 2 2 0 Adenovirus hexon-associated protein (IX) Hist_deacetyl PF00850.19 PSC71162.1 - 4.3e-45 154.5 0.0 5.6e-45 154.1 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain IQ PF00612.27 PSC71163.1 - 7.7e-11 40.8 6.2 5.8e-05 22.5 0.4 3.1 2 0 0 2 2 2 2 IQ calmodulin-binding motif Lebercilin PF15619.6 PSC71163.1 - 0.0064 16.2 19.4 0.0064 16.2 19.4 2.1 2 0 0 2 2 2 1 Ciliary protein causing Leber congenital amaurosis disease Leu_zip PF15294.6 PSC71163.1 - 0.85 9.1 10.6 1.7 8.1 10.6 1.4 1 0 0 1 1 1 0 Leucine zipper RNA_pol_Rpb5_N PF03871.14 PSC71163.1 - 6.9 7.3 7.0 2.2 8.9 3.0 2.2 2 1 0 2 2 2 0 RNA polymerase Rpb5, N-terminal domain Nucleotid_trans PF03407.16 PSC71164.1 - 3.7e-16 59.7 0.0 2e-08 34.5 0.0 2.3 2 0 0 2 2 2 2 Nucleotide-diphospho-sugar transferase Nucleotid_trans PF03407.16 PSC71165.1 - 6.8e-16 58.9 0.0 2.8e-08 34.0 0.0 2.3 2 0 0 2 2 2 2 Nucleotide-diphospho-sugar transferase AAA_2 PF07724.14 PSC71166.1 - 1.5e-60 204.2 0.8 1.5e-56 191.2 0.0 3.2 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 PSC71166.1 - 5e-33 113.1 0.9 5e-33 113.1 0.9 3.0 1 1 1 3 3 3 1 AAA lid domain AAA PF00004.29 PSC71166.1 - 5.7e-28 98.0 0.6 8.3e-15 55.4 0.0 3.5 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 PSC71166.1 - 5.3e-24 84.1 3.8 8e-24 83.5 1.7 2.6 2 0 0 2 2 1 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 PSC71166.1 - 1.9e-22 79.1 0.1 4.6e-11 42.7 0.0 2.9 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 PSC71166.1 - 7.1e-19 68.2 1.1 8.6e-13 48.5 0.0 3.9 4 1 0 4 4 3 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 PSC71166.1 - 2.8e-10 40.2 0.1 2e-06 27.6 0.0 2.8 2 1 0 2 2 2 2 Sigma-54 interaction domain AAA_16 PF13191.6 PSC71166.1 - 4e-10 40.3 9.4 0.00019 21.9 0.1 5.1 4 3 1 6 6 4 2 AAA ATPase domain AAA_22 PF13401.6 PSC71166.1 - 5.8e-10 39.6 4.1 0.0005 20.3 0.0 5.0 2 2 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 PSC71166.1 - 2.1e-07 30.8 0.0 0.032 14.0 0.0 3.0 2 0 0 2 2 2 2 IstB-like ATP binding protein TniB PF05621.11 PSC71166.1 - 7.3e-07 28.8 0.0 0.00034 20.1 0.0 3.6 2 1 0 2 2 2 1 Bacterial TniB protein AAA_18 PF13238.6 PSC71166.1 - 9.1e-06 26.2 0.0 0.14 12.7 0.0 3.3 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 PSC71166.1 - 1e-05 25.5 0.0 0.3 11.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 PSC71166.1 - 1.6e-05 24.4 0.3 1.1 8.6 0.0 3.5 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 PSC71166.1 - 2.8e-05 23.9 2.4 0.47 10.2 0.0 3.9 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 PSC71166.1 - 3.5e-05 23.6 0.0 0.11 12.2 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 PSC71166.1 - 5.5e-05 22.8 0.0 0.03 13.8 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 PSC71166.1 - 0.00011 21.6 0.0 0.034 13.4 0.0 2.8 2 0 0 2 2 2 1 Zeta toxin ResIII PF04851.15 PSC71166.1 - 0.00015 21.8 0.0 0.19 11.7 0.0 3.9 4 1 0 4 4 3 1 Type III restriction enzyme, res subunit RNA_helicase PF00910.22 PSC71166.1 - 0.00025 21.4 0.0 0.92 9.9 0.0 3.0 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.12 PSC71166.1 - 0.00026 20.9 0.0 0.24 11.3 0.1 3.4 2 1 0 2 2 2 1 NACHT domain AAA_33 PF13671.6 PSC71166.1 - 0.00033 20.9 0.0 0.69 10.1 0.0 3.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 PSC71166.1 - 0.00067 19.9 1.2 0.73 10.1 0.0 3.6 3 1 0 3 3 3 1 AAA domain Roc PF08477.13 PSC71166.1 - 0.00081 19.6 0.0 0.39 10.9 0.0 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 PSC71166.1 - 0.0016 18.3 0.1 1.9 8.4 0.0 3.5 4 0 0 4 4 3 1 RsgA GTPase TsaE PF02367.17 PSC71166.1 - 0.0018 18.3 0.0 1.6 8.8 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 PSC71166.1 - 0.0032 17.3 0.2 1.1 9.1 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 PSC71166.1 - 0.0089 15.8 0.0 0.87 9.4 0.0 3.0 3 0 0 3 3 3 1 DNA polymerase III, delta subunit Torsin PF06309.11 PSC71166.1 - 0.012 15.7 0.0 0.11 12.6 0.0 2.3 2 0 0 2 2 2 0 Torsin ATPase_2 PF01637.18 PSC71166.1 - 0.014 15.3 10.1 1.3 8.9 0.1 5.0 5 2 1 6 6 5 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 PSC71166.1 - 0.03 14.8 0.7 1.9 9.0 0.0 3.2 3 1 0 3 3 2 0 ABC transporter SRP54 PF00448.22 PSC71166.1 - 0.032 13.9 0.0 1.1 8.8 0.0 2.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_19 PF13245.6 PSC71166.1 - 0.033 14.5 0.3 1.5 9.2 0.0 3.1 2 2 0 2 2 2 0 AAA domain Ribosomal_L9_C PF03948.14 PSC71166.1 - 0.058 13.9 1.7 0.15 12.5 0.1 2.5 2 0 0 2 2 1 0 Ribosomal protein L9, C-terminal domain PBS_linker_poly PF00427.21 PSC71166.1 - 0.058 13.4 0.0 0.22 11.6 0.0 2.0 1 0 0 1 1 1 0 Phycobilisome Linker polypeptide AAA_25 PF13481.6 PSC71166.1 - 0.059 12.9 0.0 2.8 7.5 0.0 3.1 2 0 0 2 2 2 0 AAA domain YfcL PF08891.11 PSC71166.1 - 0.067 13.5 2.2 0.19 12.1 0.1 2.7 2 0 0 2 2 2 0 YfcL protein PduV-EutP PF10662.9 PSC71166.1 - 0.11 12.2 0.0 2 8.2 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PCI PF01399.27 PSC71166.1 - 0.16 12.5 1.0 2 9.0 0.2 2.9 2 1 0 2 2 2 0 PCI domain DUF4407 PF14362.6 PSC71166.1 - 0.29 10.4 9.1 0.88 8.9 9.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TolA_bind_tri PF16331.5 PSC71166.1 - 1.6 8.9 11.6 3.2 7.9 5.3 3.8 2 1 1 3 3 3 0 TolA binding protein trimerisation DUF1843 PF08898.10 PSC71166.1 - 2.6 8.6 9.4 2.8 8.5 0.0 5.0 6 0 0 6 6 3 0 Domain of unknown function (DUF1843) FAM76 PF16046.5 PSC71166.1 - 6.1 6.1 7.1 13 5.0 1.3 2.4 2 0 0 2 2 2 0 FAM76 protein FlxA PF14282.6 PSC71166.1 - 8.2 6.5 9.5 1.2 9.2 2.3 2.6 2 0 0 2 2 2 0 FlxA-like protein Histone_H2A_C PF16211.5 PSC71167.1 - 1.6e-20 72.5 2.1 3.3e-20 71.5 2.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 PSC71167.1 - 1.8e-15 57.4 0.0 2.3e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC71167.1 - 1.5e-05 25.1 0.0 2.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Peptidase_M11 PF05548.11 PSC71168.1 - 2.4e-16 59.8 0.3 3.7e-16 59.2 0.3 1.2 1 0 0 1 1 1 1 Gametolysin peptidase M11 Histone PF00125.24 PSC71168.1 - 3.3e-14 53.3 0.0 5.4e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Peptidase_M66 PF10462.9 PSC71168.1 - 0.049 12.6 1.7 0.079 11.9 1.7 1.2 1 0 0 1 1 1 0 Peptidase M66 CBFD_NFYB_HMF PF00808.23 PSC71168.1 - 0.085 13.2 1.2 0.2 11.9 0.1 2.0 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SelR PF01641.18 PSC71169.1 - 0.0016 18.5 2.5 0.12 12.4 0.0 3.1 3 0 0 3 3 3 1 SelR domain Yippee-Mis18 PF03226.14 PSC71169.1 - 0.0033 17.6 6.9 0.0068 16.6 0.0 3.0 2 1 1 3 3 3 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly FAM72 PF14976.6 PSC71169.1 - 0.0095 16.1 0.1 0.0095 16.1 0.1 2.2 3 0 0 3 3 3 1 FAM72 protein ADD_ATRX PF17981.1 PSC71169.1 - 1.6 8.7 5.6 3.4 7.6 0.1 3.1 3 0 0 3 3 3 0 Cysteine Rich ADD domain MTHFR_C PF12225.8 PSC71169.1 - 3.4 7.4 8.1 8.4 6.1 0.2 3.1 3 0 0 3 3 3 0 Methylene-tetrahydrofolate reductase C terminal Histone PF00125.24 PSC71170.1 - 2.9e-54 183.0 1.9 3.2e-54 182.8 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 PSC71170.1 - 0.00013 22.5 1.7 0.00016 22.2 1.7 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 PSC71170.1 - 0.00045 20.5 0.0 0.00069 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 PSC71170.1 - 0.00049 20.2 0.5 0.00074 19.6 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 PSC71170.1 - 0.0052 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PSC71170.1 - 0.016 15.3 0.1 0.031 14.3 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Pkinase PF00069.25 PSC71171.1 - 1.8e-46 158.6 0.0 2.7e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC71171.1 - 2.6e-17 63.0 0.0 4.2e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Sec8_exocyst PF04048.14 PSC71171.1 - 1.3e-13 51.0 0.0 2.6e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 PSC71171.1 - 3.9e-08 32.9 0.0 6.4e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Kinase-like PF14531.6 PSC71171.1 - 0.0013 18.1 0.0 0.0031 16.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 PSC71171.1 - 0.046 12.7 0.0 0.069 12.1 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Pkinase PF00069.25 PSC71172.1 - 1.7e-46 158.7 0.0 2.6e-46 158.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC71172.1 - 2.5e-17 63.0 0.0 4.1e-17 62.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Sec8_exocyst PF04048.14 PSC71172.1 - 1.3e-13 51.1 0.0 2.5e-13 50.1 0.0 1.4 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Vps54_N PF10475.9 PSC71172.1 - 3.8e-08 33.0 0.0 6.1e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex Kinase-like PF14531.6 PSC71172.1 - 0.0012 18.2 0.0 0.0029 16.9 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pox_ser-thr_kin PF05445.11 PSC71172.1 - 0.045 12.7 0.0 0.067 12.2 0.0 1.1 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase PPI_Ypi1 PF07491.11 PSC71173.1 - 9.3e-24 83.0 1.0 9.3e-24 83.0 1.0 1.7 2 0 0 2 2 2 1 Protein phosphatase inhibitor LCE PF14672.6 PSC71173.1 - 0.21 12.2 4.8 0.59 10.8 1.5 2.2 2 0 0 2 2 2 0 Late cornified envelope Mpv17_PMP22 PF04117.12 PSC71174.1 - 3e-20 72.2 1.6 3e-20 72.2 1.6 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family TMEM135_C_rich PF15982.5 PSC71174.1 - 3.8e-17 63.2 0.3 4.5e-07 30.5 0.0 3.3 3 0 0 3 3 3 2 N-terminal cysteine-rich region of Transmembrane protein 135 SUKH_6 PF14568.6 PSC71174.1 - 0.08 13.4 0.0 4 7.9 0.0 2.2 2 0 0 2 2 2 0 SMI1-KNR4 cell-wall Ubiquitin_2 PF14560.6 PSC71175.1 - 8.7e-27 93.4 0.0 1.3e-26 92.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 PSC71175.1 - 2e-23 82.2 3.1 3.2e-23 81.5 3.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain ubiquitin PF00240.23 PSC71175.1 - 0.015 15.1 0.0 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin family ACOX PF01756.19 PSC71176.1 - 6e-30 104.1 0.0 1.1e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 PSC71176.1 - 6.5e-17 61.5 0.0 1.1e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 PSC71176.1 - 7.7e-12 45.7 0.0 2e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.11 PSC71176.1 - 0.0016 18.8 0.1 0.006 16.9 0.1 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Esterase PF00756.20 PSC71177.1 - 1.8e-49 168.7 0.0 2.1e-49 168.5 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 PSC71177.1 - 1.8e-06 27.4 0.1 5.4e-06 25.9 0.1 1.7 1 1 1 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 PSC71177.1 - 1.1e-05 25.1 0.1 1.4e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.7 PSC71177.1 - 0.0013 19.4 0.7 0.0022 18.7 0.7 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 PSC71177.1 - 0.013 14.4 0.0 0.019 13.9 0.0 1.4 1 1 0 1 1 1 0 Chlorophyllase enzyme Esterase_phd PF10503.9 PSC71177.1 - 0.018 14.5 0.0 2.4 7.6 0.0 2.0 2 0 0 2 2 2 0 Esterase PHB depolymerase Abhydrolase_1 PF00561.20 PSC71177.1 - 0.02 14.6 0.0 0.031 13.9 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Chlorophyllase PF07224.11 PSC71177.1 - 0.14 11.2 0.0 0.22 10.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase zf-MYND PF01753.18 PSC71178.1 - 3.5e-08 33.4 13.6 3.5e-08 33.4 13.6 2.2 2 0 0 2 2 2 1 MYND finger MRP PF09387.10 PSC71178.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial RNA binding protein MRP Nodulin-like PF06813.13 PSC71179.1 - 8.1e-35 120.5 8.7 1.2e-34 119.9 8.7 1.3 1 0 0 1 1 1 1 Nodulin-like Nodulin-like PF06813.13 PSC71180.1 - 1.5e-36 126.1 9.3 2.3e-36 125.6 9.3 1.3 1 0 0 1 1 1 1 Nodulin-like MFS_1 PF07690.16 PSC71180.1 - 1.1e-12 47.5 47.1 5.7e-10 38.7 17.3 3.9 3 1 0 4 4 4 3 Major Facilitator Superfamily CN_hydrolase PF00795.22 PSC71181.1 - 2.4e-36 125.4 0.0 3.2e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase AAA_16 PF13191.6 PSC71182.1 - 7.4e-06 26.4 0.0 1.2e-05 25.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain MeaB PF03308.16 PSC71182.1 - 1.5e-05 24.2 0.0 2.1e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB PRK PF00485.18 PSC71182.1 - 0.00068 19.4 0.0 0.0011 18.8 0.0 1.4 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 PSC71182.1 - 0.0011 18.4 0.0 0.0016 17.8 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin Viral_helicase1 PF01443.18 PSC71182.1 - 0.0015 18.3 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ATP_bind_1 PF03029.17 PSC71182.1 - 0.0016 18.3 0.0 0.0021 17.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_18 PF13238.6 PSC71182.1 - 0.0025 18.4 0.0 0.0042 17.6 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PSC71182.1 - 0.0077 16.4 0.1 0.017 15.3 0.0 1.7 2 0 0 2 2 2 1 AAA domain NB-ARC PF00931.22 PSC71182.1 - 0.027 13.7 0.0 0.038 13.2 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 PSC71182.1 - 0.046 14.2 0.0 0.069 13.6 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 PSC71182.1 - 0.053 13.6 0.1 0.081 13.0 0.1 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 PSC71182.1 - 0.063 13.4 0.0 0.088 12.9 0.0 1.1 1 0 0 1 1 1 0 Helicase HerA, central domain NACHT PF05729.12 PSC71182.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DUF815 PF05673.13 PSC71182.1 - 0.095 11.8 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF815) NTPase_1 PF03266.15 PSC71182.1 - 0.1 12.5 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 NTPase Thymidylate_kin PF02223.17 PSC71182.1 - 0.11 12.2 0.0 0.53 9.9 0.0 1.9 2 0 0 2 2 2 0 Thymidylate kinase AAA_5 PF07728.14 PSC71182.1 - 0.12 12.3 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) cobW PF02492.19 PSC71182.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.2 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_17 PF13207.6 PSC71182.1 - 0.15 12.5 0.1 3.9 7.9 0.1 2.2 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 PSC71182.1 - 0.22 11.0 0.0 0.32 10.4 0.0 1.1 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Beach PF02138.18 PSC71183.1 - 2.4e-103 345.3 0.0 3.2e-103 344.9 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain FGGY_C PF02782.16 PSC71183.1 - 1.1e-13 51.4 1.1 2.4e-13 50.3 0.1 2.1 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain PH_BEACH PF14844.6 PSC71183.1 - 2.5e-06 27.5 0.0 2.7e-05 24.2 0.0 2.6 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH Arm PF00514.23 PSC71183.1 - 8.1e-05 22.5 10.3 0.082 13.0 0.3 4.9 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat FGGY_N PF00370.21 PSC71183.1 - 0.00042 20.0 0.0 0.001 18.7 0.0 1.6 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain GRAM PF02893.20 PSC71183.1 - 0.0005 19.9 0.0 0.018 14.9 0.0 2.3 2 0 0 2 2 2 1 GRAM domain Beach PF02138.18 PSC71184.1 - 7.1e-105 350.3 0.0 9.2e-105 350.0 0.0 1.1 1 0 0 1 1 1 1 Beige/BEACH domain Acyltransferase PF01553.21 PSC71184.1 - 1.6e-12 47.2 0.0 3.8e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase WD40 PF00400.32 PSC71184.1 - 0.001 19.9 0.7 4 8.5 0.0 4.3 3 0 0 3 3 3 1 WD domain, G-beta repeat PH_BEACH PF14844.6 PSC71184.1 - 0.058 13.5 0.0 17 5.6 0.0 3.5 3 1 0 3 3 3 0 PH domain associated with Beige/BEACH GRAM PF02893.20 PSC71184.1 - 0.1 12.5 0.0 0.79 9.6 0.0 2.1 2 0 0 2 2 2 0 GRAM domain Usp PF00582.26 PSC71185.1 - 0.0001 22.8 4.4 0.00048 20.7 4.4 2.0 1 1 0 1 1 1 1 Universal stress protein family Histone PF00125.24 PSC71186.1 - 6.3e-12 46.0 0.2 6.3e-12 46.0 0.2 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC71186.1 - 0.03 14.6 0.1 0.03 14.6 0.1 2.8 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PSC71187.1 - 6.3e-12 46.0 0.2 6.3e-12 46.0 0.2 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC71187.1 - 0.03 14.6 0.1 0.03 14.6 0.1 2.8 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF2470 PF10615.9 PSC71188.1 - 1e-09 38.9 0.0 1.8e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Pyrid_oxidase_2 PF13883.6 PSC71188.1 - 1e-08 35.4 0.0 1.6e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Putative_PNPOx PF01243.20 PSC71188.1 - 4.4e-08 33.2 0.0 8.7e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase RibD_C PF01872.17 PSC71189.1 - 2.5e-37 128.7 0.0 4.1e-37 128.0 0.0 1.4 1 0 0 1 1 1 1 RibD C-terminal domain DUF1768 PF08719.11 PSC71189.1 - 1.4e-21 77.4 0.0 1.8e-14 54.3 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF1768) Peptidase_M11 PF05548.11 PSC71189.1 - 6.8e-11 41.9 0.0 1.1e-10 41.2 0.0 1.2 1 0 0 1 1 1 1 Gametolysin peptidase M11 Peptidase_M66 PF10462.9 PSC71189.1 - 0.091 11.7 0.4 0.17 10.8 0.4 1.4 1 0 0 1 1 1 0 Peptidase M66 zf-MYND PF01753.18 PSC71190.1 - 4.9e-09 36.1 13.1 9.7e-09 35.2 13.1 1.5 1 0 0 1 1 1 1 MYND finger Lar_restr_allev PF14354.6 PSC71190.1 - 0.15 12.5 6.3 0.56 10.6 6.4 1.9 2 0 0 2 2 2 0 Restriction alleviation protein Lar Chloroa_b-bind PF00504.21 PSC71191.1 - 6.1e-05 23.6 0.0 7e-05 23.4 0.0 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein DLH PF01738.18 PSC71191.1 - 0.098 12.2 0.0 0.11 12.0 0.0 1.0 1 0 0 1 1 1 0 Dienelactone hydrolase family CAF1C_H4-bd PF12265.8 PSC71192.1 - 9.2e-28 96.3 0.6 3.8e-27 94.3 0.2 2.3 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 PSC71192.1 - 6.4e-24 83.8 10.1 8e-06 26.5 0.0 5.7 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.11 PSC71192.1 - 1.4e-05 25.1 0.4 0.00054 19.9 0.0 3.2 3 1 1 4 4 4 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 PSC71192.1 - 0.0012 19.1 1.5 0.25 11.7 0.1 4.0 2 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain RINGv PF12906.7 PSC71193.1 - 4.4e-10 39.5 6.4 6.7e-10 38.9 6.4 1.3 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 PSC71193.1 - 0.00026 21.3 4.8 0.0005 20.3 4.8 1.5 1 0 0 1 1 1 1 Ring finger domain MscS_TM PF12794.7 PSC71193.1 - 0.00043 19.2 0.1 0.00055 18.9 0.1 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 TMEM208_SND2 PF05620.11 PSC71193.1 - 0.043 13.6 0.1 0.059 13.1 0.1 1.1 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 zf-C3HC4 PF00097.25 PSC71193.1 - 0.36 10.7 3.0 2.8 7.9 3.0 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PITH PF06201.13 PSC71196.1 - 4.3e-33 114.7 0.0 6.3e-33 114.1 0.0 1.3 1 0 0 1 1 1 1 PITH domain MOSC_N PF03476.16 PSC71196.1 - 6.3e-32 110.0 0.0 1.4e-31 108.9 0.0 1.6 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 PSC71196.1 - 2.1e-27 95.7 0.0 6.8e-27 94.1 0.0 1.9 2 0 0 2 2 2 1 MOSC domain rve PF00665.26 PSC71196.1 - 1.6e-18 67.0 0.0 4e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC71196.1 - 0.014 15.1 0.0 0.037 13.8 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain TFIIF_beta PF02270.15 PSC71197.1 - 7.7e-19 67.6 0.5 1.4e-18 66.8 0.5 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 PSC71197.1 - 9.4e-09 36.1 0.1 1.9e-08 35.1 0.0 1.7 2 1 0 2 2 2 1 TFIIF, beta subunit N-terminus Tau95 PF09734.9 PSC71197.1 - 0.00069 20.4 0.1 0.0013 19.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Sin_N PF04801.13 PSC71197.1 - 0.015 14.6 0.3 0.024 13.9 0.3 1.3 1 0 0 1 1 1 0 Sin-like protein conserved region Malic_M PF03949.15 PSC71198.1 - 2.5e-86 289.1 0.1 3.6e-86 288.6 0.1 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 PSC71198.1 - 1.9e-63 213.5 0.0 2.8e-63 213.0 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain FA_desaturase PF00487.24 PSC71199.1 - 2.1e-36 126.1 15.8 3.7e-36 125.3 15.8 1.3 1 0 0 1 1 1 1 Fatty acid desaturase DUF3474 PF11960.8 PSC71199.1 - 8.9e-10 38.9 0.0 1.8e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3474) Sulfotransfer_3 PF13469.6 PSC71199.1 - 0.0034 17.8 0.4 2.1 8.7 0.2 2.8 1 1 1 2 2 2 2 Sulfotransferase family TruB_N PF01509.18 PSC71200.1 - 3.9e-48 163.6 0.0 9.6e-48 162.3 0.0 1.6 2 0 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 PSC71200.1 - 4.8e-08 33.0 0.2 1.2e-07 31.7 0.2 1.7 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain adh_short PF00106.25 PSC71201.1 - 8.9e-23 80.8 0.0 2.3e-17 63.1 0.0 2.2 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PSC71201.1 - 1.3e-12 47.8 0.0 6.1e-11 42.3 0.0 2.2 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC71201.1 - 0.003 17.5 0.1 0.0057 16.6 0.1 1.4 1 0 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 PSC71201.1 - 0.016 15.4 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 PSC71201.1 - 0.14 12.0 0.0 0.28 11.0 0.0 1.5 1 0 0 1 1 1 0 NAD(P)H-binding ApbA PF02558.16 PSC71201.1 - 0.15 11.7 0.1 0.28 10.8 0.1 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DnaJ PF00226.31 PSC71202.1 - 1.6e-10 40.9 0.0 3.4e-10 39.9 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 PSC71202.1 - 7.8e-10 38.1 33.9 0.0057 16.7 0.4 7.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_17 PF13431.6 PSC71202.1 - 1e-05 25.6 4.4 0.63 10.5 0.0 4.9 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 PSC71202.1 - 1.9e-05 24.3 5.8 0.044 13.6 0.1 5.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 PSC71202.1 - 0.021 15.6 7.5 0.021 15.6 7.5 10.1 7 5 4 11 11 11 0 Tetratricopeptide repeat TPR_16 PF13432.6 PSC71202.1 - 0.026 15.2 16.7 0.026 15.2 16.7 7.4 7 1 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.6 PSC71202.1 - 0.03 14.5 7.0 0.61 10.4 0.0 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_6 PF13174.6 PSC71202.1 - 0.039 14.6 0.2 0.039 14.6 0.2 6.6 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 PSC71202.1 - 0.12 12.6 38.3 0.29 11.3 5.3 5.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.6 PSC71202.1 - 1.1 8.9 0.0 1.1 8.9 0.0 4.7 5 0 0 5 5 5 0 TPR repeat TPR_19 PF14559.6 PSC71202.1 - 1.4 9.4 59.7 0.13 12.7 2.4 7.0 6 1 1 7 7 7 0 Tetratricopeptide repeat ER_lumen_recept PF00810.18 PSC71203.1 - 1.7e-53 181.4 9.1 2.9e-53 180.6 9.1 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 PSC71203.1 - 0.03 14.1 11.0 0.11 12.3 0.1 3.7 4 0 0 4 4 4 0 PQ loop repeat Ist1 PF03398.14 PSC71204.1 - 2e-38 131.9 0.2 2.7e-38 131.5 0.2 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Pkinase PF00069.25 PSC71205.1 - 3.2e-65 220.1 0.0 8.3e-42 143.4 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC71205.1 - 6.5e-29 101.0 0.0 5.7e-21 75.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PSC71205.1 - 0.0015 17.9 0.0 0.011 15.1 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 PSC71205.1 - 0.0029 17.6 0.0 0.0029 17.6 0.0 3.2 3 0 0 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PSC71205.1 - 0.0099 14.9 0.0 0.015 14.3 0.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 PSC71205.1 - 0.093 12.3 0.0 11 5.6 0.0 2.3 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RHH_1 PF01402.21 PSC71205.1 - 0.1 12.6 0.6 0.43 10.6 0.6 2.1 1 0 0 1 1 1 0 Ribbon-helix-helix protein, copG family Methyltransf_15 PF09445.10 PSC71206.1 - 2.6e-36 124.7 0.0 4.7e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase WW PF00397.26 PSC71206.1 - 1.6e-08 34.5 2.7 3.1e-08 33.6 2.7 1.5 1 0 0 1 1 1 1 WW domain Cons_hypoth95 PF03602.15 PSC71206.1 - 0.0091 15.7 0.0 0.0091 15.7 0.0 2.1 3 0 0 3 3 3 1 Conserved hypothetical protein 95 Met_10 PF02475.16 PSC71206.1 - 0.2 11.4 0.0 0.31 10.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein UCH PF00443.29 PSC71207.1 - 7.4e-31 107.6 0.0 1e-30 107.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 PSC71207.1 - 1.5e-12 47.6 1.3 2.7e-12 46.8 1.3 1.3 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 PSC71207.1 - 0.023 14.3 0.0 3.8 7.0 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase UPF0183 PF03676.14 PSC71208.1 - 2.6e-66 224.6 0.0 3.4e-58 197.8 0.0 2.8 3 0 0 3 3 3 2 Uncharacterised protein family (UPF0183) PPR_2 PF13041.6 PSC71209.1 - 1.4e-40 137.3 0.0 5.4e-10 39.3 0.0 7.8 6 2 2 8 8 8 7 PPR repeat family PPR PF01535.20 PSC71209.1 - 2e-27 93.5 3.0 0.0076 16.4 0.0 9.5 9 0 0 9 9 9 8 PPR repeat PPR_3 PF13812.6 PSC71209.1 - 2.1e-24 85.4 0.0 1.1e-10 41.4 0.0 4.4 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 PSC71209.1 - 3.1e-24 85.5 0.4 1.1e-10 41.2 0.1 3.2 2 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 PSC71209.1 - 8e-15 54.2 0.7 0.0022 17.7 0.1 6.4 6 0 0 6 6 6 4 PPR repeat Smr PF01713.21 PSC71209.1 - 0.00038 20.7 0.1 0.0011 19.2 0.1 1.8 1 0 0 1 1 1 1 Smr domain GMP_synt_C PF00958.22 PSC71209.1 - 0.012 15.7 0.0 0.97 9.5 0.0 2.9 2 1 1 3 3 3 0 GMP synthase C terminal domain TPR_2 PF07719.17 PSC71209.1 - 1.3 9.3 4.3 2.1 8.6 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Histone PF00125.24 PSC71210.1 - 1e-15 58.3 0.0 1.2e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC71210.1 - 0.0077 16.5 0.1 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DnaJ PF00226.31 PSC71210.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain RP-C PF03428.13 PSC71210.1 - 0.06 13.0 0.4 3.4 7.3 0.0 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain TFIID_20kDa PF03847.13 PSC71210.1 - 0.2 12.2 0.0 0.33 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A RsgA_GTPase PF03193.16 PSC71211.1 - 2.4e-46 157.7 0.0 9e-32 110.3 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 PSC71211.1 - 0.00037 20.5 0.0 0.24 11.5 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 PSC71211.1 - 0.0004 20.4 0.0 0.00073 19.5 0.0 1.3 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain ABC_tran PF00005.27 PSC71211.1 - 0.0012 19.4 0.8 0.0043 17.6 0.0 2.3 3 0 0 3 3 3 1 ABC transporter AAA_29 PF13555.6 PSC71211.1 - 0.0015 18.3 0.0 0.0035 17.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 PSC71211.1 - 0.0018 18.8 0.0 0.0036 17.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain IIGP PF05049.13 PSC71211.1 - 0.0096 15.0 0.3 0.018 14.1 0.1 1.4 2 0 0 2 2 2 1 Interferon-inducible GTPase (IIGP) Dynamin_N PF00350.23 PSC71211.1 - 0.023 14.8 0.1 1.9 8.5 0.1 2.5 2 0 0 2 2 2 0 Dynamin family SMC_N PF02463.19 PSC71211.1 - 0.03 13.8 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PSC71211.1 - 0.031 14.7 1.0 0.031 14.7 1.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain GTP_EFTU PF00009.27 PSC71211.1 - 0.042 13.4 0.0 0.27 10.8 0.0 2.2 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain AAA_21 PF13304.6 PSC71211.1 - 0.045 13.6 0.0 0.065 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system cobW PF02492.19 PSC71211.1 - 0.088 12.4 0.1 2.7 7.5 0.1 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SOCS PF12610.8 PSC71211.1 - 1.3 9.5 9.6 0.7 10.3 5.1 2.5 2 0 0 2 2 2 0 Suppressor of cytokine signalling CENP-T_C PF15511.6 PSC71213.1 - 2e-08 34.3 0.1 2.5e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PSC71213.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 PSC71213.1 - 0.00022 21.3 0.1 0.00031 20.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 PSC71213.1 - 0.0011 18.9 0.1 0.0017 18.4 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 PSC71213.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PSC71213.1 - 0.0015 18.9 0.1 0.0017 18.8 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 PSC71213.1 - 0.033 14.3 0.0 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit GST_N_3 PF13417.6 PSC71214.1 - 1.4e-17 63.9 0.0 3.1e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Peptidase_M43 PF05572.13 PSC71214.1 - 6.7e-16 58.6 0.0 1.2e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 Pregnancy-associated plasma protein-A GST_N_2 PF13409.6 PSC71214.1 - 1.4e-13 50.9 0.0 3.5e-13 49.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PSC71214.1 - 5.1e-11 42.8 0.1 1.3e-10 41.5 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_5 PF16865.5 PSC71214.1 - 6.2e-07 30.0 0.0 1.1e-06 29.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PSC71214.1 - 2.2e-06 27.6 0.1 7.7e-06 25.8 0.1 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Reprolysin_5 PF13688.6 PSC71214.1 - 0.012 15.7 0.4 0.022 14.9 0.4 1.4 1 0 0 1 1 1 0 Metallo-peptidase family M12 GST_C PF00043.25 PSC71214.1 - 0.016 15.4 0.0 0.032 14.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Reprolysin_4 PF13583.6 PSC71214.1 - 0.055 13.1 1.5 0.065 12.9 0.0 1.7 2 0 0 2 2 2 0 Metallo-peptidase family M12B Reprolysin-like Peptidase_M7 PF02031.16 PSC71214.1 - 0.084 13.0 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Streptomyces extracellular neutral proteinase (M7) family GST_C_3 PF14497.6 PSC71214.1 - 0.18 12.0 0.0 0.33 11.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain DNA_pol_E_B PF04042.16 PSC71215.1 - 2e-38 131.9 0.0 2.9e-38 131.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 PSC71215.1 - 8.2e-37 126.2 0.0 1.3e-36 125.6 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain Rad21_Rec8_N PF04825.13 PSC71215.1 - 4e-21 75.2 0.0 7.5e-21 74.4 0.0 1.3 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 PSC71215.1 - 7.4e-09 34.8 0.0 1.7e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Conserved region of Rad21 / Rec8 like protein 2OG-FeII_Oxy_3 PF13640.6 PSC71216.1 - 1.8e-18 67.2 0.0 2.9e-18 66.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 PSC71216.1 - 1e-09 38.8 0.0 1.8e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 PSC71216.1 - 4.2e-07 30.4 4.3 7.5e-07 29.6 3.4 1.9 2 0 0 2 2 2 1 ShK domain-like Tail_spike_N PF18668.1 PSC71216.1 - 0.031 14.1 0.0 0.067 13.1 0.0 1.5 1 0 0 1 1 1 0 Tail spike TSP1/Gp66 receptor binding N-terminal domain Pox_C4_C10 PF03336.13 PSC71216.1 - 0.12 11.5 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Poxvirus C4/C10 protein 2OG-FeII_Oxy_3 PF13640.6 PSC71217.1 - 1.7e-18 67.3 0.0 2.8e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 PSC71217.1 - 9.7e-10 38.8 0.0 1.7e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 PSC71217.1 - 1.1e-06 29.0 8.3 1.9e-06 28.3 7.4 1.9 2 0 0 2 2 2 1 ShK domain-like Tail_spike_N PF18668.1 PSC71217.1 - 0.029 14.2 0.0 0.064 13.1 0.0 1.5 1 0 0 1 1 1 0 Tail spike TSP1/Gp66 receptor binding N-terminal domain Pox_C4_C10 PF03336.13 PSC71217.1 - 0.11 11.5 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Poxvirus C4/C10 protein Steroid_dh PF02544.16 PSC71218.1 - 4.8e-29 101.3 0.0 8.2e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 PSC71218.1 - 0.00018 21.9 0.3 0.00054 20.3 0.3 1.8 1 0 0 1 1 1 1 Phospholipid methyltransferase adh_short PF00106.25 PSC71219.1 - 4.1e-51 173.2 0.2 5.2e-51 172.9 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC71219.1 - 4.9e-36 124.5 0.6 6e-36 124.2 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC71219.1 - 1.6e-13 51.0 0.7 2.1e-13 50.6 0.7 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PSC71219.1 - 0.00019 21.0 0.1 0.00049 19.6 0.1 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 PSC71219.1 - 0.0042 16.3 0.1 0.0071 15.5 0.1 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein ApbA PF02558.16 PSC71219.1 - 0.0056 16.3 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Herpes_UL56 PF04534.12 PSC71219.1 - 0.019 14.5 0.1 0.031 13.7 0.1 1.3 1 0 0 1 1 1 0 Herpesvirus UL56 protein MoCF_biosynth PF00994.24 PSC71220.1 - 2e-20 73.0 0.0 3.6e-20 72.1 0.0 1.4 1 1 0 1 1 1 1 Probable molybdopterin binding domain CorA PF01544.18 PSC71221.1 - 0.00011 21.6 0.7 0.00033 20.1 0.0 1.8 2 0 0 2 2 2 1 CorA-like Mg2+ transporter protein FbpA PF05833.11 PSC71221.1 - 0.043 12.6 0.2 1.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Fibronectin-binding protein A N-terminus (FbpA) PAS_12 PF18095.1 PSC71221.1 - 0.15 11.7 0.0 0.31 10.7 0.0 1.4 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain CbiG_C PF01890.16 PSC71221.1 - 0.19 12.3 1.1 1.7 9.3 0.1 2.4 2 0 0 2 2 2 0 Cobalamin synthesis G C-terminus Asp_Arg_Hydrox PF05118.15 PSC71222.1 - 0.013 15.3 0.1 0.43 10.4 0.0 2.5 2 0 0 2 2 2 0 Aspartyl/Asparaginyl beta-hydroxylase MRP-S31 PF15433.6 PSC71222.1 - 0.025 14.3 4.2 0.048 13.3 4.2 1.4 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 DUF4915 PF16261.5 PSC71222.1 - 0.057 12.6 0.0 0.17 11.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4915) Kinesin PF00225.23 PSC71223.1 - 1.2e-91 307.1 0.0 1.9e-91 306.5 0.0 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PSC71223.1 - 6.2e-22 78.1 0.0 1.1e-21 77.4 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding zf-MYND PF01753.18 PSC71223.1 - 1.1e-07 31.9 4.9 3.2e-07 30.3 4.9 1.8 1 0 0 1 1 1 1 MYND finger DUF2722 PF10846.8 PSC71224.1 - 0.052 12.5 15.4 0.076 11.9 15.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DDHD PF02862.17 PSC71224.1 - 0.11 12.6 2.4 0.18 12.0 2.4 1.3 1 0 0 1 1 1 0 DDHD domain Spt20 PF12090.8 PSC71224.1 - 0.15 11.7 22.8 0.23 11.0 22.8 1.2 1 0 0 1 1 1 0 Spt20 family OATP PF03137.20 PSC71224.1 - 0.22 9.7 0.4 0.32 9.2 0.4 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family SOG2 PF10428.9 PSC71224.1 - 0.24 10.6 7.6 0.36 10.0 7.6 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 PSC71224.1 - 0.52 9.0 5.6 0.73 8.5 5.6 1.1 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 PSC71224.1 - 0.85 7.7 3.6 1.1 7.3 3.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDC27 PF09507.10 PSC71224.1 - 1.2 8.5 12.0 2.2 7.6 12.0 1.4 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Suf PF05843.14 PSC71224.1 - 1.8 8.5 8.8 2.9 7.8 8.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ANAPC_CDC26 PF10471.9 PSC71224.1 - 1.8 9.5 22.4 3.9 8.4 22.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 DUF4834 PF16118.5 PSC71224.1 - 2.1 9.4 10.7 3.6 8.6 10.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) AIF_C PF14721.6 PSC71224.1 - 2.5 8.5 5.9 4.4 7.7 5.9 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term UPF0560 PF10577.9 PSC71224.1 - 4.1 5.8 11.3 5.9 5.3 11.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Roughex PF06020.11 PSC71224.1 - 4.5 6.3 11.5 6.8 5.7 11.5 1.2 1 0 0 1 1 1 0 Drosophila roughex protein PAT1 PF09770.9 PSC71224.1 - 5.4 5.2 13.7 7.3 4.7 13.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Tim54 PF11711.8 PSC71224.1 - 5.9 5.6 6.8 9.6 4.9 6.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Herpes_DNAp_acc PF04929.12 PSC71224.1 - 6 5.7 8.0 11 4.9 8.0 1.3 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DMRL_synthase PF00885.19 PSC71225.1 - 2.8e-52 176.3 4.3 1.2e-51 174.3 0.5 2.1 2 0 0 2 2 2 2 6,7-dimethyl-8-ribityllumazine synthase cNMP_binding PF00027.29 PSC71226.1 - 4.3e-78 257.5 2.6 1.2e-19 70.1 0.0 4.7 4 0 0 4 4 4 4 Cyclic nucleotide-binding domain Pkinase PF00069.25 PSC71226.1 - 2.1e-65 220.7 0.0 3.4e-65 220.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC71226.1 - 1.2e-30 106.6 0.0 2.8e-30 105.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase rve PF00665.26 PSC71226.1 - 2.7e-18 66.3 0.0 6.5e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Ephrin_rec_like PF07699.13 PSC71226.1 - 4e-05 23.3 22.8 0.00036 20.2 7.3 6.4 4 1 3 7 7 7 3 Putative ephrin-receptor like Kinase-like PF14531.6 PSC71226.1 - 0.0016 17.8 0.0 0.0026 17.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like rve_3 PF13683.6 PSC71226.1 - 0.026 14.3 0.1 0.059 13.1 0.1 1.5 1 0 0 1 1 1 0 Integrase core domain Cupin_2 PF07883.11 PSC71226.1 - 0.27 11.0 5.1 2.8 7.7 0.1 3.7 3 0 0 3 3 3 0 Cupin domain Histone_H2A_C PF16211.5 PSC71227.1 - 1.1e-20 73.1 1.3 2.1e-20 72.1 1.3 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 PSC71227.1 - 2.1e-15 57.2 0.0 2.6e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC71227.1 - 1.5e-05 25.2 0.0 2.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SNase PF00565.17 PSC71228.1 - 3.8e-40 136.7 0.8 3.7e-11 43.5 0.0 6.3 6 1 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.24 PSC71228.1 - 3.3e-18 65.9 0.0 8.6e-18 64.5 0.0 1.7 2 0 0 2 2 2 1 Tudor domain SNase PF00565.17 PSC71229.1 - 3.4e-40 136.9 0.6 3.7e-11 43.4 0.0 6.3 6 1 0 6 6 6 5 Staphylococcal nuclease homologue TUDOR PF00567.24 PSC71229.1 - 3.4e-18 65.8 0.0 8.8e-18 64.5 0.0 1.7 2 0 0 2 2 2 1 Tudor domain Mito_carr PF00153.27 PSC71230.1 - 8.5e-57 189.1 1.8 4.9e-21 74.4 0.0 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein PLAT PF01477.23 PSC71232.1 - 2.2e-87 289.4 0.0 3.4e-16 59.9 0.0 7.2 6 1 1 7 7 7 7 PLAT/LH2 domain ATS3 PF06232.11 PSC71232.1 - 6e-09 35.9 0.0 0.0029 17.5 0.0 4.1 4 0 0 4 4 4 2 Embryo-specific protein 3, (ATS3) PH PF00169.29 PSC71232.1 - 7.9e-06 26.3 0.0 0.25 11.9 0.0 2.8 3 0 0 3 3 3 2 PH domain Endothelin PF00322.17 PSC71232.1 - 0.13 11.9 2.3 0.72 9.5 0.3 2.6 2 0 0 2 2 2 0 Endothelin family AAA_13 PF13166.6 PSC71232.1 - 9.8 4.7 15.3 15 4.1 15.3 1.1 1 0 0 1 1 1 0 AAA domain ETF PF01012.21 PSC71234.1 - 2e-38 132.1 13.7 2e-38 132.1 13.7 1.6 2 0 0 2 2 2 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 PSC71234.1 - 2.1e-34 117.4 0.8 8.1e-34 115.5 0.8 2.1 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain DUF1279 PF06916.13 PSC71235.1 - 2.6e-21 76.0 0.0 4.2e-21 75.3 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1279) Bystin PF05291.11 PSC71236.1 - 7.3e-129 429.2 0.2 9.3e-129 428.9 0.2 1.1 1 0 0 1 1 1 1 Bystin MTHFR PF02219.17 PSC71237.1 - 0.0031 16.9 0.0 0.0046 16.3 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase PH PF00169.29 PSC71238.1 - 4.1e-21 75.5 0.1 5e-21 75.2 0.1 1.1 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PSC71238.1 - 8e-07 29.4 2.0 1.1e-05 25.8 2.0 2.1 1 1 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 PSC71238.1 - 0.00011 22.5 0.0 0.0002 21.7 0.0 1.4 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 PSC71238.1 - 0.00091 19.3 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_2 PF08458.10 PSC71238.1 - 0.039 14.3 0.0 0.055 13.8 0.0 1.2 1 0 0 1 1 1 0 Plant pleckstrin homology-like region PH_13 PF16652.5 PSC71238.1 - 0.064 13.1 0.0 0.087 12.6 0.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain Glucokinase PF02685.16 PSC71239.1 - 3.5e-86 289.1 0.0 4.3e-86 288.8 0.0 1.0 1 0 0 1 1 1 1 Glucokinase muHD PF10291.9 PSC71240.1 - 0.071 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Muniscin C-terminal mu homology domain LRR_8 PF13855.6 PSC71241.1 - 0.00035 20.3 4.1 0.048 13.4 0.3 4.1 3 2 2 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 PSC71241.1 - 0.002 18.5 1.2 0.47 10.9 0.1 3.8 3 1 1 4 4 4 1 Leucine Rich repeats (2 copies) RNA_pol_N PF01194.17 PSC71242.1 - 5.9e-32 109.8 1.0 6.8e-32 109.6 1.0 1.1 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Alg6_Alg8 PF03155.15 PSC71243.1 - 3.9e-120 402.1 0.0 4.8e-120 401.8 0.0 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family WD40 PF00400.32 PSC71246.1 - 1.2e-54 181.1 20.6 5.4e-08 33.4 0.1 11.3 11 0 0 11 11 11 10 WD domain, G-beta repeat Utp12 PF04003.12 PSC71246.1 - 2.1e-19 69.8 1.8 3.5e-19 69.1 1.8 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 PSC71246.1 - 3e-14 53.1 0.7 0.0092 16.3 0.0 7.5 5 3 4 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PSC71246.1 - 3.1e-07 29.4 1.1 0.25 10.0 0.0 4.9 4 1 1 5 5 5 2 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 PSC71246.1 - 1.1e-06 27.9 3.5 0.0028 16.7 0.9 4.6 4 1 1 5 5 5 2 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 PSC71246.1 - 7e-05 22.3 0.0 0.093 12.0 0.0 3.6 4 0 0 4 4 4 1 WD40-like domain Ge1_WD40 PF16529.5 PSC71246.1 - 0.00038 19.5 2.3 1.5 7.7 0.0 5.5 4 2 3 7 7 7 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 PSC71246.1 - 0.034 12.9 0.0 1.3 7.7 0.0 3.5 3 2 3 6 6 6 0 Nup133 N terminal like Utp21 PF04192.12 PSC71246.1 - 0.13 11.7 0.2 0.27 10.7 0.2 1.5 1 0 0 1 1 1 0 Utp21 specific WD40 associated putative domain BHD_2 PF10404.9 PSC71246.1 - 0.99 10.4 3.5 2.6 9.1 3.5 1.6 1 0 0 1 1 1 0 Rad4 beta-hairpin domain 2 Histidinol_dh PF00815.20 PSC71248.1 - 1.4e-159 531.5 0.1 1.6e-159 531.3 0.1 1.0 1 0 0 1 1 1 1 Histidinol dehydrogenase CorA PF01544.18 PSC71249.1 - 2.1e-08 33.9 1.3 3.7e-06 26.5 0.0 2.4 2 1 0 2 2 2 2 CorA-like Mg2+ transporter protein Ovate PF04844.13 PSC71249.1 - 0.00095 19.1 0.6 0.0028 17.6 0.6 1.7 1 0 0 1 1 1 1 Transcriptional repressor, ovate Atrophin-1 PF03154.15 PSC71249.1 - 0.0066 14.8 5.8 0.011 14.1 5.8 1.2 1 0 0 1 1 1 1 Atrophin-1 family FUSC PF04632.12 PSC71249.1 - 5.5 5.4 12.1 0.2 10.2 0.2 2.2 1 1 1 2 2 2 0 Fusaric acid resistance protein family SBP PF03110.14 PSC71250.1 - 2.7e-23 82.1 7.9 3.7e-23 81.6 7.9 1.2 1 0 0 1 1 1 1 SBP domain FMN_dh PF01070.18 PSC71251.1 - 1.3e-66 225.0 0.0 1.9e-66 224.5 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 PSC71251.1 - 3.6e-07 29.9 0.6 5.6e-07 29.3 0.6 1.2 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.14 PSC71251.1 - 1.3e-06 27.9 0.3 0.0064 15.8 0.7 2.2 1 1 1 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.25 PSC71251.1 - 3.2e-06 26.4 0.5 1.6e-05 24.1 0.3 1.9 1 1 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain PsbP PF01789.16 PSC71251.1 - 8.7e-06 25.9 0.0 0.056 13.6 0.0 2.1 2 0 0 2 2 2 2 PsbP Glu_synthase PF01645.17 PSC71251.1 - 4.4e-05 22.8 0.2 6.9e-05 22.1 0.2 1.3 1 0 0 1 1 1 1 Conserved region in glutamate synthase DHO_dh PF01180.21 PSC71251.1 - 0.00077 18.8 0.1 0.0013 18.1 0.1 1.4 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase Dus PF01207.17 PSC71251.1 - 0.016 14.4 0.0 0.13 11.3 0.0 1.9 1 1 1 2 2 2 0 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 PSC71251.1 - 0.023 14.1 0.0 0.049 13.1 0.0 1.4 1 1 0 1 1 1 0 Histidine biosynthesis protein G3P_antiterm PF04309.12 PSC71251.1 - 0.16 11.4 0.0 0.36 10.2 0.1 1.6 1 1 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator zf-PARP PF00645.18 PSC71252.1 - 1.2e-17 64.5 0.0 2.3e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-PARP PF00645.18 PSC71253.1 - 1e-17 64.7 0.0 1.9e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-PARP PF00645.18 PSC71254.1 - 1e-17 64.7 0.0 1.9e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-PARP PF00645.18 PSC71255.1 - 1e-17 64.7 0.0 1.9e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region CotH PF08757.11 PSC71256.1 - 9.3e-27 94.4 0.0 1.8e-26 93.5 0.0 1.5 1 1 0 1 1 1 1 CotH kinase protein NUMOD3 PF07460.11 PSC71256.1 - 4.9e-05 23.5 0.0 0.0084 16.3 0.0 2.8 2 0 0 2 2 2 2 NUMOD3 motif (2 copies) Drc1-Sld2 PF11719.8 PSC71256.1 - 0.013 15.1 0.0 0.013 15.1 0.0 2.1 3 0 0 3 3 3 0 DNA replication and checkpoint protein CotH PF08757.11 PSC71257.1 - 9.3e-27 94.4 0.0 1.8e-26 93.5 0.0 1.5 1 1 0 1 1 1 1 CotH kinase protein NUMOD3 PF07460.11 PSC71257.1 - 4.9e-05 23.5 0.0 0.0084 16.3 0.0 2.8 2 0 0 2 2 2 2 NUMOD3 motif (2 copies) Drc1-Sld2 PF11719.8 PSC71257.1 - 0.013 15.1 0.0 0.013 15.1 0.0 2.1 3 0 0 3 3 3 0 DNA replication and checkpoint protein PPR_2 PF13041.6 PSC71258.1 - 4.7e-21 74.7 0.0 7.9e-08 32.4 0.0 3.7 2 2 2 4 4 4 4 PPR repeat family PPR_3 PF13812.6 PSC71258.1 - 5.1e-15 55.3 0.0 1.6e-06 28.0 0.0 2.4 2 0 0 2 2 2 2 Pentatricopeptide repeat domain PPR PF01535.20 PSC71258.1 - 1.5e-10 40.6 1.7 0.00046 20.2 0.0 3.9 5 0 0 5 5 5 2 PPR repeat PPR_1 PF12854.7 PSC71258.1 - 3.5e-08 33.0 0.0 0.0029 17.3 0.0 4.6 5 0 0 5 5 5 2 PPR repeat PPR_long PF17177.4 PSC71258.1 - 1.9e-07 30.7 0.1 1.3e-06 28.0 0.1 1.9 1 1 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP Get5_C PF18514.1 PSC71258.1 - 0.08 12.7 0.2 10 5.9 0.0 3.0 3 0 0 3 3 3 0 Get5 C-terminal domain MRP-S27 PF10037.9 PSC71258.1 - 0.19 10.6 0.0 6.6 5.5 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 Sec23_trunk PF04811.15 PSC71259.1 - 2.8e-73 246.5 0.0 4.8e-73 245.7 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 PSC71259.1 - 4.8e-21 75.3 0.0 8e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 PSC71259.1 - 3.8e-20 71.6 0.0 6e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 PSC71259.1 - 8.2e-15 54.6 2.3 1.5e-14 53.8 2.3 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 PSC71259.1 - 0.00043 20.1 0.0 0.00083 19.2 0.0 1.4 1 0 0 1 1 1 1 Gelsolin repeat VWA_2 PF13519.6 PSC71259.1 - 0.049 14.3 0.2 0.62 10.7 0.0 2.5 3 0 0 3 3 3 0 von Willebrand factor type A domain WD40 PF00400.32 PSC71260.1 - 1.5e-18 66.8 11.2 1.6e-06 28.7 0.1 5.6 5 0 0 5 5 5 3 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 PSC71260.1 - 9.2e-17 61.1 0.1 6.2e-15 55.2 0.0 2.7 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 PSC71260.1 - 6.7e-06 26.3 0.1 0.011 16.1 0.3 3.5 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PSC71260.1 - 3.2 6.3 6.2 2.7 6.5 0.2 3.1 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Transglut_core3 PF13471.6 PSC71261.1 - 4.5e-05 23.3 1.1 0.00022 21.1 0.1 2.1 1 1 1 2 2 2 1 Transglutaminase-like superfamily Pkinase PF00069.25 PSC71262.1 - 3.5e-42 144.6 0.0 1.1e-41 142.9 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC71262.1 - 2.7e-39 135.0 0.0 1.8e-38 132.3 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PSC71262.1 - 0.044 13.7 3.5 1.6 8.6 0.1 2.8 2 1 0 3 3 3 0 Phosphotransferase enzyme family Kdo PF06293.14 PSC71262.1 - 0.096 12.0 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PSC71262.1 - 0.23 10.2 0.0 0.43 9.3 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase VSP PF03302.13 PSC71262.1 - 0.38 9.6 3.3 0.59 8.9 3.3 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein zf-MYND PF01753.18 PSC71263.1 - 2.9e-05 24.1 8.1 2.9e-05 24.1 8.1 1.9 2 0 0 2 2 2 1 MYND finger TFIIA PF03153.13 PSC71263.1 - 2.9 7.8 11.1 4.9 7.0 11.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit OGG_N PF07934.12 PSC71264.1 - 1.9e-22 79.6 0.0 2.5e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 PSC71264.1 - 3.1e-08 34.0 0.2 5e-07 30.2 0.1 2.2 2 1 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 PSC71264.1 - 0.00013 21.7 0.5 0.00055 19.7 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_2 PF12826.7 PSC71264.1 - 0.0098 16.0 0.1 1 9.5 0.0 2.4 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH_5 PF14520.6 PSC71264.1 - 0.013 16.1 0.1 0.32 11.6 0.0 2.4 2 0 0 2 2 2 0 Helix-hairpin-helix domain HHH_8 PF14716.6 PSC71264.1 - 0.065 13.6 0.0 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 Helix-hairpin-helix domain AAA_16 PF13191.6 PSC71265.1 - 1.9e-11 44.6 6.6 3.4e-06 27.6 0.4 3.8 3 1 0 3 3 3 2 AAA ATPase domain Guanylate_cyc PF00211.20 PSC71265.1 - 3.8e-10 39.7 0.0 9.4e-07 28.6 0.0 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AAA_22 PF13401.6 PSC71265.1 - 0.0055 17.0 0.1 2.2 8.6 0.0 3.4 2 1 0 2 2 2 1 AAA domain STAS PF01740.21 PSC71265.1 - 0.19 11.4 0.0 0.72 9.5 0.0 1.8 2 0 0 2 2 2 0 STAS domain DGF-1_C PF11040.8 PSC71267.1 - 0.057 13.4 0.2 0.057 13.4 0.2 3.2 2 2 3 5 5 5 0 Dispersed gene family protein 1 of Trypanosoma cruzi C-terminus MMACHC PF16690.5 PSC71268.1 - 1.4e-08 34.6 0.0 2.7e-07 30.5 0.0 2.6 2 1 0 2 2 2 1 Methylmalonic aciduria and homocystinuria type C family DUF4051 PF13260.6 PSC71268.1 - 0.55 10.0 4.2 21 5.0 4.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4051) DNA_pol_E_B PF04042.16 PSC71269.1 - 2.7e-27 95.5 0.0 3.5e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Pol_alpha_B_N PF08418.10 PSC71269.1 - 0.0043 17.1 0.0 0.0062 16.5 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal AAA_30 PF13604.6 PSC71270.1 - 3e-40 138.0 0.1 1.2e-39 136.0 0.0 2.1 2 0 0 2 2 1 1 AAA domain AAA_19 PF13245.6 PSC71270.1 - 2.3e-28 99.4 0.0 4.4e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain SH3_13 PF18335.1 PSC71270.1 - 6.5e-17 61.1 0.0 1.3e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 ATP-dependent RecD-like DNA helicase SH3 domain UvrD_C_2 PF13538.6 PSC71270.1 - 3.1e-16 58.9 0.9 6.4e-16 57.9 0.9 1.6 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain HHH_4 PF14490.6 PSC71270.1 - 4.6e-15 55.4 0.0 2.1e-14 53.3 0.0 2.2 2 0 0 2 2 1 1 Helix-hairpin-helix containing domain Viral_helicase1 PF01443.18 PSC71270.1 - 6.3e-08 32.6 2.4 0.0048 16.7 0.1 3.1 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase HHH_5 PF14520.6 PSC71270.1 - 6.7e-08 33.0 0.3 0.0049 17.4 0.1 3.4 2 0 0 2 2 2 2 Helix-hairpin-helix domain AAA_11 PF13086.6 PSC71270.1 - 1e-06 28.8 1.2 0.038 13.8 0.4 2.3 2 0 0 2 2 2 2 AAA domain HHH PF00633.23 PSC71270.1 - 7.1e-06 25.6 3.2 0.2 11.6 0.1 3.8 3 0 0 3 3 3 2 Helix-hairpin-helix motif Helicase_RecD PF05127.14 PSC71270.1 - 0.00032 20.6 0.0 0.00091 19.1 0.0 1.8 1 0 0 1 1 1 1 Helicase AAA_16 PF13191.6 PSC71270.1 - 0.004 17.6 3.5 0.0044 17.4 0.1 2.9 3 1 1 4 4 3 1 AAA ATPase domain NACHT PF05729.12 PSC71270.1 - 0.0045 16.9 0.9 0.01 15.8 0.3 1.9 2 0 0 2 2 2 1 NACHT domain AAA PF00004.29 PSC71270.1 - 0.0083 16.6 0.0 0.016 15.6 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 PSC71270.1 - 0.015 14.6 0.1 0.03 13.6 0.1 1.4 1 0 0 1 1 1 0 Zeta toxin UvrD_C PF13361.6 PSC71270.1 - 0.018 14.4 0.1 0.032 13.6 0.1 1.3 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain T2SSE PF00437.20 PSC71270.1 - 0.019 14.0 0.1 0.73 8.8 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DNA_pol_lambd_f PF10391.9 PSC71270.1 - 0.02 14.7 0.4 64 3.5 0.2 3.7 3 0 0 3 3 3 0 Fingers domain of DNA polymerase lambda MeaB PF03308.16 PSC71270.1 - 0.023 13.7 0.7 0.1 11.6 0.3 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Rad17 PF03215.15 PSC71270.1 - 0.026 14.4 0.0 0.047 13.6 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain HHH_2 PF12826.7 PSC71270.1 - 0.031 14.4 0.0 0.96 9.6 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix motif NTPase_1 PF03266.15 PSC71270.1 - 0.037 13.9 0.1 0.069 13.1 0.1 1.4 1 0 0 1 1 1 0 NTPase AAA_22 PF13401.6 PSC71270.1 - 0.042 14.1 0.4 0.15 12.4 0.4 1.9 1 1 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 PSC71270.1 - 0.062 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PIF1 PF05970.14 PSC71270.1 - 0.064 12.4 0.3 1.4 8.1 0.1 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_28 PF13521.6 PSC71270.1 - 0.08 13.2 4.7 0.11 12.7 0.2 2.6 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 PSC71270.1 - 0.14 12.3 0.0 0.46 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 PSC71270.1 - 0.14 11.6 0.1 0.25 10.7 0.1 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_5 PF07728.14 PSC71270.1 - 0.19 11.7 0.1 0.46 10.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) TsaE PF02367.17 PSC71270.1 - 0.22 11.5 0.1 0.45 10.5 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 PSC71270.1 - 0.26 11.8 1.6 0.78 10.2 0.2 2.1 1 1 1 2 2 2 0 ABC transporter AAA_17 PF13207.6 PSC71270.1 - 0.43 11.0 2.1 0.52 10.7 0.8 1.8 2 0 0 2 2 1 0 AAA domain DDOST_48kD PF03345.14 PSC71272.1 - 4.5e-108 361.8 0.0 5e-108 361.6 0.0 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta PC4 PF02229.16 PSC71273.1 - 8.5e-82 268.7 0.0 4.8e-21 74.2 0.0 4.2 4 0 0 4 4 4 4 Transcriptional Coactivator p15 (PC4) DEK_C PF08766.11 PSC71273.1 - 3.2e-05 23.8 0.0 0.00012 22.0 0.0 1.9 2 0 0 2 2 2 1 DEK C terminal domain Rieske_2 PF13806.6 PSC71274.1 - 1.3e-16 60.4 0.0 2e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 PSC71274.1 - 0.011 15.6 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 PSC71275.1 - 1.2e-16 60.5 0.0 2e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Rieske PF00355.26 PSC71275.1 - 0.011 15.6 0.0 0.019 14.9 0.0 1.4 1 0 0 1 1 1 0 Rieske [2Fe-2S] domain DHHA1 PF02272.19 PSC71276.1 - 0.017 15.6 0.0 0.017 15.6 0.0 1.6 2 0 0 2 2 2 0 DHHA1 domain DHH PF01368.20 PSC71276.1 - 0.03 14.6 0.0 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 DHH family GDC-P PF02347.16 PSC71277.1 - 3.1e-187 622.7 2.1 2e-178 593.7 0.1 2.8 3 0 0 3 3 3 2 Glycine cleavage system P-protein SNF2_N PF00176.23 PSC71277.1 - 1.7e-25 89.5 0.0 4.3e-25 88.2 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain FKBP_C PF00254.28 PSC71277.1 - 4.9e-11 42.8 0.0 1e-10 41.8 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Helicase_C PF00271.31 PSC71277.1 - 5.8e-10 39.5 0.0 1.8e-09 38.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain TPR_2 PF07719.17 PSC71277.1 - 3.9e-05 23.4 10.2 0.092 12.9 3.5 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 PSC71277.1 - 8.2e-05 22.3 6.3 0.4 10.6 1.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 PSC71277.1 - 0.00029 20.9 9.9 0.0015 18.6 9.9 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 PSC71277.1 - 0.00094 18.8 2.3 0.8 9.4 0.1 2.7 2 0 0 2 2 2 2 TPR repeat TPR_6 PF13174.6 PSC71277.1 - 0.012 16.2 6.2 5.1 8.0 0.0 4.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 PSC71277.1 - 0.039 14.5 16.2 0.015 15.8 9.8 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 PSC71277.1 - 0.26 11.6 3.5 3.5 8.1 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat CtaG_Cox11 PF04442.14 PSC71278.1 - 1.1e-62 210.6 0.1 1.5e-62 210.1 0.1 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 TilS PF09179.11 PSC71278.1 - 0.0068 16.9 7.6 0.014 15.9 7.6 1.5 1 0 0 1 1 1 1 TilS substrate binding domain Carboxyl_trans PF01039.22 PSC71279.1 - 3.3e-180 600.0 0.0 4.1e-180 599.7 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain Herpes_capsid PF06112.11 PSC71280.1 - 6 6.9 11.9 8.3 6.4 11.9 1.3 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Lipase_3 PF01764.25 PSC71281.1 - 7.8e-23 80.9 0.1 4e-07 30.0 0.0 3.4 3 0 0 3 3 3 3 Lipase (class 3) DUF2974 PF11187.8 PSC71281.1 - 0.033 13.8 0.0 1.7 8.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) TMEM144 PF07857.12 PSC71282.1 - 1.3e-10 40.7 3.6 3.1e-10 39.5 3.6 1.6 1 1 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 PSC71282.1 - 5.2e-06 26.0 14.1 0.0015 17.9 3.9 2.2 2 0 0 2 2 2 2 Sugar transport protein Histone PF00125.24 PSC71283.1 - 2.5e-15 57.0 0.1 3.2e-15 56.6 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC71283.1 - 0.0086 16.3 0.1 0.018 15.3 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DnaJ PF00226.31 PSC71283.1 - 0.067 13.3 0.0 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain Pentapeptide PF00805.22 PSC71284.1 - 7.6e-20 70.2 26.9 3.1e-08 33.1 0.5 3.3 1 1 3 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 PSC71284.1 - 1.1e-09 38.4 0.6 0.00093 19.3 0.5 2.2 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 PSC71284.1 - 1.9e-06 27.9 1.5 0.051 13.7 1.5 3.1 1 1 0 1 1 1 1 Pentapeptide repeats (9 copies) TPR_7 PF13176.6 PSC71285.1 - 0.0098 15.9 1.3 6.4 7.1 0.1 3.4 2 0 0 2 2 2 2 Tetratricopeptide repeat SPO22 PF08631.10 PSC71285.1 - 0.23 10.9 8.7 7.2 6.0 0.3 3.8 3 1 1 4 4 4 0 Meiosis protein SPO22/ZIP4 like SnoaL_2 PF12680.7 PSC71285.1 - 0.87 10.3 4.4 0.6 10.8 0.8 2.7 2 0 0 2 2 2 0 SnoaL-like domain Glyco_hydro_9 PF00759.19 PSC71286.1 - 2.1e-114 383.2 4.9 2.7e-114 382.8 4.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Sugar_tr PF00083.24 PSC71286.1 - 8.4e-57 193.0 21.3 4.5e-40 137.9 2.6 3.1 2 1 1 3 3 3 3 Sugar (and other) transporter ShK PF01549.24 PSC71286.1 - 0.0039 17.7 4.6 0.0094 16.5 4.6 1.6 1 0 0 1 1 1 1 ShK domain-like DEAD PF00270.29 PSC71287.1 - 6.7e-48 162.8 0.0 1.1e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC71287.1 - 3.1e-25 88.7 0.0 1.5e-24 86.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 PSC71287.1 - 1.4e-12 47.7 3.8 4.2e-12 46.1 3.8 1.9 1 0 0 1 1 1 1 DBP10CT (NUC160) domain ResIII PF04851.15 PSC71287.1 - 5.5e-06 26.5 0.0 1e-05 25.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 PSC71287.1 - 0.15 11.3 0.0 0.27 10.4 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase ubiquitin PF00240.23 PSC71288.1 - 0.008 15.9 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family rve PF00665.26 PSC71289.1 - 1.1e-18 67.6 0.0 3.6e-18 65.9 0.0 2.0 1 0 0 1 1 1 1 Integrase core domain HAUS5 PF14817.6 PSC71289.1 - 8.2e-12 44.7 25.0 1.3e-11 44.1 25.0 1.3 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 rve_3 PF13683.6 PSC71289.1 - 0.0073 16.1 0.0 0.034 13.9 0.0 2.2 1 0 0 1 1 1 1 Integrase core domain Glyco_tran_28_C PF04101.16 PSC71289.1 - 0.36 10.8 2.3 0.61 10.0 0.3 2.3 2 0 0 2 2 2 0 Glycosyltransferase family 28 C-terminal domain T2SSF PF00482.23 PSC71289.1 - 2.6 8.0 13.4 0.52 10.3 0.8 3.9 2 1 1 3 3 3 0 Type II secretion system (T2SS), protein F CBM_20 PF00686.19 PSC71290.1 - 1.5e-14 53.6 0.0 3.4e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Starch binding domain R3H PF01424.22 PSC71290.1 - 0.00083 19.3 0.0 0.0017 18.3 0.0 1.5 1 0 0 1 1 1 1 R3H domain Ank_5 PF13857.6 PSC71290.1 - 0.12 12.7 0.0 0.34 11.3 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Kinesin PF00225.23 PSC71291.1 - 8.4e-94 314.2 0.0 2e-93 312.9 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain SNF2_N PF00176.23 PSC71291.1 - 6.2e-74 248.8 0.0 9.8e-74 248.1 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain HIRAN PF08797.11 PSC71291.1 - 4.5e-16 58.6 0.0 9e-16 57.6 0.0 1.5 1 0 0 1 1 1 1 HIRAN domain Microtub_bd PF16796.5 PSC71291.1 - 4.2e-14 52.7 0.0 2.5e-13 50.2 0.0 2.3 2 1 0 2 2 2 1 Microtubule binding Helicase_C PF00271.31 PSC71291.1 - 1.2e-11 44.9 0.0 3.1e-11 43.6 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 PSC71291.1 - 4.1e-09 36.1 9.1 7.4e-09 35.3 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC71291.1 - 3.5e-08 33.2 7.8 5.6e-08 32.5 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC71291.1 - 9.6e-08 31.8 8.3 1.7e-07 31.0 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CENP-T_C PF15511.6 PSC71291.1 - 7.5e-07 29.2 0.0 2.8e-06 27.4 0.0 2.0 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold zf-RING_2 PF13639.6 PSC71291.1 - 2e-06 28.0 9.2 3.8e-06 27.1 9.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PSC71291.1 - 2.6e-06 27.3 5.5 4.8e-06 26.4 5.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PSC71291.1 - 3.8e-06 27.0 8.6 7.1e-06 26.1 8.6 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PSC71291.1 - 5.5e-06 26.1 7.6 1e-05 25.3 7.6 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PSC71291.1 - 8.4e-06 25.7 9.5 1.8e-05 24.7 9.5 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 PSC71291.1 - 0.00042 20.5 2.3 0.00094 19.4 2.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 PSC71291.1 - 0.0006 19.6 2.8 0.0014 18.5 2.8 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein DEAD PF00270.29 PSC71291.1 - 0.0023 17.7 0.0 0.21 11.3 0.0 2.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase zf-Nse PF11789.8 PSC71291.1 - 0.0039 17.0 4.1 0.0088 15.8 4.1 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit CENP-S PF15630.6 PSC71291.1 - 0.007 16.7 0.0 0.017 15.5 0.0 1.6 1 0 0 1 1 1 1 CENP-S protein TAF PF02969.17 PSC71291.1 - 0.0082 16.3 0.0 0.025 14.7 0.0 1.9 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) ResIII PF04851.15 PSC71291.1 - 0.027 14.5 0.8 21 5.1 0.0 3.9 4 0 0 4 4 3 0 Type III restriction enzyme, res subunit DUF5546 PF17700.1 PSC71291.1 - 0.034 14.5 0.0 0.08 13.3 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5546) zf-ANAPC11 PF12861.7 PSC71291.1 - 0.037 14.1 0.7 0.1 12.7 0.7 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Bromo_TP PF07524.13 PSC71291.1 - 0.038 14.0 0.1 0.096 12.7 0.1 1.6 1 0 0 1 1 1 0 Bromodomain associated CBFD_NFYB_HMF PF00808.23 PSC71291.1 - 0.16 12.3 0.0 0.16 12.3 0.0 2.4 3 0 0 3 3 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone zf-RING_10 PF16685.5 PSC71291.1 - 0.95 9.6 5.4 2.1 8.6 5.4 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 DEAD_2 PF06733.15 PSC71291.1 - 1.8 8.1 4.1 0.86 9.2 0.0 2.2 2 0 0 2 2 2 0 DEAD_2 zf-RING_4 PF14570.6 PSC71291.1 - 2.3 8.1 5.2 5 7.0 5.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 PSC71291.1 - 3.9 7.3 5.6 8.1 6.3 5.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger ABC_membrane PF00664.23 PSC71292.1 - 1.3e-56 192.2 10.6 1.3e-56 192.2 10.6 1.5 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 PSC71292.1 - 1.6e-32 112.9 0.0 3.4e-32 111.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PSC71292.1 - 1.4e-08 34.4 1.5 1.4e-06 27.9 0.1 2.2 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PSC71292.1 - 1.1e-05 25.8 1.7 4.7e-05 23.8 0.4 2.7 2 1 0 2 2 2 1 AAA ATPase domain ABC_ATPase PF09818.9 PSC71292.1 - 0.0018 17.2 0.7 0.0028 16.5 0.0 1.6 2 0 0 2 2 2 1 Predicted ATPase of the ABC class AAA_22 PF13401.6 PSC71292.1 - 0.0072 16.6 0.2 0.082 13.2 0.0 2.6 2 1 0 2 2 2 1 AAA domain Bunya_G2 PF03563.13 PSC71292.1 - 0.037 13.3 0.0 0.19 11.0 0.1 1.8 2 0 0 2 2 2 0 Bunyavirus glycoprotein G2 AAA PF00004.29 PSC71292.1 - 0.067 13.6 1.6 6.9 7.1 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 PSC71292.1 - 0.081 12.7 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain SbcCD_C PF13558.6 PSC71292.1 - 0.096 12.9 1.0 1.6 9.0 1.0 2.9 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit CPP1-like PF11833.8 PSC71292.1 - 0.55 9.9 7.3 0.052 13.2 1.6 2.2 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like CPSase_L_D2 PF02786.17 PSC71293.1 - 1.6e-80 269.6 0.1 2.7e-80 268.9 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 PSC71293.1 - 1.3e-42 144.8 0.1 2.9e-42 143.7 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 PSC71293.1 - 4e-40 136.3 0.0 9.4e-40 135.1 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 PSC71293.1 - 1.7e-15 56.6 0.5 3.8e-15 55.5 0.5 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 PSC71293.1 - 4.2e-09 36.2 0.0 8e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 PSC71293.1 - 9.6e-09 35.1 0.0 2.4e-08 33.8 0.0 1.6 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus PCC_BT PF18140.1 PSC71293.1 - 2.4e-07 31.1 0.0 6.3e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain ATP-grasp_3 PF02655.14 PSC71293.1 - 1e-05 25.6 0.0 0.00021 21.4 0.0 2.3 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.6 PSC71293.1 - 6.8e-05 22.6 1.9 0.00038 20.2 0.0 2.4 1 1 1 2 2 2 1 Biotin-lipoyl like HlyD_3 PF13437.6 PSC71293.1 - 0.0018 19.0 0.6 0.0065 17.2 0.1 2.1 1 1 1 2 2 2 1 HlyD family secretion protein RimK PF08443.11 PSC71293.1 - 0.02 14.5 0.0 0.053 13.1 0.0 1.6 1 1 0 1 1 1 0 RimK-like ATP-grasp domain HlyD_D23 PF16576.5 PSC71293.1 - 0.032 13.4 0.2 0.099 11.8 0.0 1.8 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion SnoaL_3 PF13474.6 PSC71293.1 - 0.18 12.1 0.0 0.43 10.8 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain GCV_H PF01597.19 PSC71293.1 - 0.19 11.6 0.2 0.62 10.0 0.1 1.8 2 0 0 2 2 2 0 Glycine cleavage H-protein DUF4605 PF15378.6 PSC71294.1 - 0.067 13.1 4.0 0.099 12.5 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4605) UvrD_C PF13361.6 PSC71295.1 - 3e-55 188.0 0.0 1.1e-29 104.0 0.0 2.3 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain UvrD-helicase PF00580.21 PSC71295.1 - 2.5e-39 135.7 0.0 4.8e-39 134.7 0.0 1.5 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain AAA_19 PF13245.6 PSC71295.1 - 5.7e-14 52.7 0.0 1.3e-13 51.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 PSC71295.1 - 6.5e-09 35.5 0.1 7.9e-08 32.0 0.1 2.4 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 PSC71295.1 - 0.00043 20.1 0.0 0.11 12.3 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase DDE_Tnp_IS240 PF13610.6 PSC71295.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 DDE domain DUF4448 PF14610.6 PSC71296.1 - 0.0023 17.8 0.0 0.003 17.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Tad PF13400.6 PSC71296.1 - 0.0036 17.6 4.7 0.0036 17.6 4.7 2.4 3 0 0 3 3 3 1 Putative Flp pilus-assembly TadE/G-like DUF3377 PF11857.8 PSC71296.1 - 0.004 17.0 0.1 0.0076 16.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) Insulin_TMD PF17870.1 PSC71296.1 - 0.0053 16.8 0.4 0.0098 15.9 0.4 1.4 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment DAG1 PF05454.11 PSC71296.1 - 0.03 13.7 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Dystroglycan (Dystrophin-associated glycoprotein 1) TMEM154 PF15102.6 PSC71296.1 - 0.035 14.0 0.0 0.051 13.5 0.0 1.2 1 0 0 1 1 1 0 TMEM154 protein family PAP_PilO PF06864.12 PSC71296.1 - 0.054 12.3 0.0 0.082 11.7 0.0 1.3 1 0 0 1 1 1 0 Pilin accessory protein (PilO) DUF4536 PF15055.6 PSC71296.1 - 0.088 13.1 1.0 0.23 11.7 1.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4536) DUF4519 PF15012.6 PSC71296.1 - 0.14 12.4 0.2 0.25 11.5 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Gram_pos_anchor PF00746.21 PSC71296.1 - 0.23 11.4 0.8 0.43 10.6 0.8 1.4 1 0 0 1 1 1 0 LPXTG cell wall anchor motif Filament PF00038.21 PSC71298.1 - 0.0025 17.5 7.4 0.0025 17.5 7.4 2.2 1 1 0 1 1 1 1 Intermediate filament protein DUF3782 PF12644.7 PSC71298.1 - 0.029 14.5 0.2 0.13 12.5 0.3 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3782) CMV_1a PF12467.8 PSC71298.1 - 0.46 10.8 5.9 0.23 11.8 0.4 2.7 2 1 1 3 3 3 0 Cucumber mosaic virus 1a protein family MPS2 PF17060.5 PSC71298.1 - 0.46 9.7 4.3 0.58 9.4 3.7 1.5 1 1 0 1 1 1 0 Monopolar spindle protein 2 CENP-F_leu_zip PF10473.9 PSC71298.1 - 0.85 9.6 14.0 0.97 9.5 5.3 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 PSC71298.1 - 0.97 8.2 21.8 0.026 13.4 7.8 2.8 2 1 0 3 3 3 0 Spc7 kinetochore protein Vps5 PF09325.10 PSC71298.1 - 8.9 5.8 11.9 13 5.3 0.7 2.8 2 1 0 2 2 2 0 Vps5 C terminal like Filament PF00038.21 PSC71299.1 - 0.0035 17.0 8.0 0.0035 17.0 8.0 2.3 1 1 0 1 1 1 1 Intermediate filament protein DUF3782 PF12644.7 PSC71299.1 - 0.05 13.8 1.5 0.12 12.5 0.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3782) MPS2 PF17060.5 PSC71299.1 - 0.47 9.7 4.4 0.61 9.3 3.8 1.5 1 1 0 1 1 1 0 Monopolar spindle protein 2 CENP-F_leu_zip PF10473.9 PSC71299.1 - 0.66 10.0 13.8 0.7 9.9 4.7 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Spc7 PF08317.11 PSC71299.1 - 0.66 8.8 22.7 0.026 13.4 7.9 3.0 2 1 0 3 3 3 0 Spc7 kinetochore protein Glyco_transf_5 PF08323.11 PSC71300.1 - 4.2e-69 232.9 0.0 6.4e-69 232.3 0.0 1.3 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 PSC71300.1 - 8.8e-19 67.7 0.0 1.8e-18 66.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PSC71300.1 - 7.8e-14 52.2 3.0 1.1e-13 51.8 0.3 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 SQS_PSY PF00494.19 PSC71301.1 - 1.4e-55 188.6 0.8 1.4e-55 188.6 0.8 1.4 2 0 0 2 2 2 1 Squalene/phytoene synthase Peptidase_M16 PF00675.20 PSC71302.1 - 1.4e-37 128.9 0.1 4.9e-37 127.2 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 PSC71302.1 - 9.1e-33 113.8 0.0 1.8e-32 112.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase M16 inactive domain EamA PF00892.20 PSC71303.1 - 0.00018 21.7 4.9 0.00018 21.7 4.9 3.3 3 1 1 4 4 4 1 EamA-like transporter family PUNUT PF16913.5 PSC71303.1 - 0.0046 16.2 0.0 0.015 14.5 0.0 1.8 2 0 0 2 2 2 1 Purine nucleobase transmembrane transport URO-D PF01208.17 PSC71303.1 - 0.16 11.1 0.1 0.24 10.5 0.1 1.2 1 0 0 1 1 1 0 Uroporphyrinogen decarboxylase (URO-D) CRT-like PF08627.10 PSC71303.1 - 0.26 10.2 0.3 2.2 7.2 0.3 2.0 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 PSC71303.1 - 0.26 10.7 3.1 0.34 10.4 1.0 2.0 2 1 0 2 2 2 0 Solute carrier family 35 TPT PF03151.16 PSC71303.1 - 0.43 9.9 2.6 0.32 10.3 0.5 1.7 2 0 0 2 2 2 0 Triose-phosphate Transporter family FAD_binding_1 PF00667.20 PSC71304.1 - 3.2e-56 190.4 0.0 4.6e-56 189.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 PSC71304.1 - 9.2e-32 110.2 0.4 9.2e-32 110.2 0.4 2.0 3 0 0 3 3 3 1 Flavodoxin NAD_binding_1 PF00175.21 PSC71304.1 - 2.5e-15 57.0 0.0 5.1e-15 56.0 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FeS_assembly_P PF01883.19 PSC71304.1 - 0.24 11.6 0.6 0.81 9.9 0.1 2.2 2 0 0 2 2 2 0 Iron-sulfur cluster assembly protein FAD_binding_1 PF00667.20 PSC71305.1 - 2.2e-56 190.9 0.0 4.6e-56 189.9 0.0 1.5 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.25 PSC71305.1 - 9.2e-32 110.2 0.4 9.2e-32 110.2 0.4 2.0 3 0 0 3 3 3 1 Flavodoxin NAD_binding_1 PF00175.21 PSC71305.1 - 5.2e-15 56.0 0.0 1e-14 55.1 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FeS_assembly_P PF01883.19 PSC71305.1 - 0.24 11.6 0.6 0.81 9.9 0.1 2.2 2 0 0 2 2 2 0 Iron-sulfur cluster assembly protein Bystin PF05291.11 PSC71306.1 - 3e-29 102.2 0.0 4.8e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Bystin Kelch_4 PF13418.6 PSC71306.1 - 3.7e-27 94.1 7.0 7.9e-08 32.2 0.0 4.8 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 PSC71306.1 - 5e-23 80.6 1.3 9e-06 25.8 0.0 5.7 4 1 1 5 5 5 4 Kelch motif Kelch_3 PF13415.6 PSC71306.1 - 4.1e-22 78.0 6.9 7.9e-08 32.4 0.3 5.1 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_1 PF01344.25 PSC71306.1 - 9.4e-22 76.3 0.2 2.6e-05 23.7 0.0 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 PSC71306.1 - 5.1e-20 71.0 0.2 0.0044 17.0 0.0 5.5 5 0 0 5 5 5 5 Kelch motif LRR_8 PF13855.6 PSC71306.1 - 1.8e-16 59.6 0.2 6.8e-08 32.2 0.0 3.5 3 0 0 3 3 3 3 Leucine rich repeat Kelch_2 PF07646.15 PSC71306.1 - 1.6e-14 53.2 3.3 0.0004 20.3 0.0 5.8 6 0 0 6 6 6 4 Kelch motif LRR_4 PF12799.7 PSC71306.1 - 1.4e-11 44.4 0.8 0.012 16.0 0.1 4.8 2 1 2 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PSC71306.1 - 0.0018 18.5 0.1 43 5.2 0.0 5.4 5 0 0 5 5 5 0 Leucine Rich Repeat Transglut_core PF01841.19 PSC71306.1 - 0.0064 16.9 0.0 0.031 14.7 0.0 2.2 1 0 0 1 1 1 1 Transglutaminase-like superfamily LRR_9 PF14580.6 PSC71306.1 - 0.069 12.7 0.0 0.24 10.9 0.0 1.8 1 1 1 2 2 2 0 Leucine-rich repeat LRR_6 PF13516.6 PSC71306.1 - 0.41 10.8 1.6 40 4.6 0.0 4.3 5 0 0 5 5 5 0 Leucine Rich repeat Glyco_hydro_43 PF04616.14 PSC71307.1 - 1.3e-09 37.8 0.2 1.7e-06 27.6 0.0 2.3 2 1 0 2 2 2 2 Glycosyl hydrolases family 43 DUF2052 PF09747.9 PSC71308.1 - 0.24 11.5 2.1 0.85 9.7 0.2 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Diphthami_syn_2 PF01902.17 PSC71309.1 - 8.4e-32 110.4 0.0 1.8e-31 109.4 0.0 1.5 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 PSC71309.1 - 5e-09 36.2 0.0 8.7e-05 22.5 0.0 2.8 2 1 0 2 2 2 2 Endoribonuclease L-PSP ECH_1 PF00378.20 PSC71310.1 - 1.4e-32 113.0 0.3 2.7e-23 82.6 1.1 2.0 2 0 0 2 2 2 2 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PSC71310.1 - 9.1e-22 78.0 0.3 2.2e-21 76.7 0.4 1.5 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase DDE_Tnp_Tn3 PF01526.17 PSC71310.1 - 0.23 10.2 0.2 0.32 9.7 0.2 1.1 1 0 0 1 1 1 0 Tn3 transposase DDE domain PhyH PF05721.13 PSC71311.1 - 5e-22 79.2 0.2 1.7e-18 67.7 0.3 2.2 1 1 1 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) ACT_4 PF13291.6 PSC71312.1 - 1.2e-05 25.8 0.0 0.13 12.9 0.0 3.5 4 0 0 4 4 4 2 ACT domain ACT PF01842.25 PSC71312.1 - 0.0012 18.5 0.0 5.4 6.9 0.0 3.7 4 0 0 4 4 4 2 ACT domain ACT_6 PF13740.6 PSC71312.1 - 0.0017 18.3 0.0 0.73 9.9 0.0 3.6 3 0 0 3 3 3 1 ACT domain Fer2 PF00111.27 PSC71313.1 - 5.3e-14 51.9 0.3 7.8e-14 51.4 0.3 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MCR PF18509.1 PSC71313.1 - 0.18 11.4 0.2 0.33 10.6 0.2 1.3 1 0 0 1 1 1 0 Magnetochrome domain Fer2 PF00111.27 PSC71314.1 - 2.8e-13 49.6 1.2 4.2e-13 49.0 1.2 1.3 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain MCR PF18509.1 PSC71314.1 - 0.19 11.3 0.2 0.35 10.5 0.2 1.3 1 0 0 1 1 1 0 Magnetochrome domain Inositol_P PF00459.25 PSC71315.1 - 8.2e-47 160.0 0.0 1.1e-46 159.6 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family DNA_pol_B PF00136.21 PSC71316.1 - 1.9e-149 498.3 0.0 2.6e-149 497.8 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 PSC71316.1 - 4.4e-78 262.8 0.0 6.1e-78 262.3 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 PSC71316.1 - 5.4e-19 68.4 5.7 1.1e-18 67.4 5.7 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta DNA_pol_B_2 PF03175.13 PSC71316.1 - 1.3e-05 24.3 0.0 2e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral DNA_pol_B_exo2 PF10108.9 PSC71316.1 - 0.006 16.3 0.0 0.011 15.5 0.0 1.4 1 0 0 1 1 1 1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 PSC71316.1 - 0.014 15.4 0.1 0.057 13.4 0.1 1.9 1 1 0 1 1 1 0 RNase_H superfamily PfkB PF00294.24 PSC71317.1 - 1.9e-36 125.9 3.5 4.5e-36 124.7 3.5 1.5 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Succ_CoA_lig PF13607.6 PSC71317.1 - 3.3 7.5 7.0 0.38 10.6 0.3 2.6 2 1 1 3 3 3 0 Succinyl-CoA ligase like flavodoxin domain Lipase_GDSL_2 PF13472.6 PSC71318.1 - 7.8e-08 32.9 0.1 3.1e-07 30.9 0.1 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.6 PSC71318.1 - 0.0055 16.9 0.0 3.4 7.8 0.0 2.2 2 0 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 PSC71318.1 - 0.018 15.0 0.0 0.087 12.8 0.0 2.0 1 1 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase Trypsin PF00089.26 PSC71320.1 - 2.5e-19 70.0 0.0 4e-19 69.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PSC71320.1 - 0.0011 19.8 0.4 0.063 14.2 0.0 2.4 1 1 1 2 2 2 1 Trypsin-like peptidase domain EamA PF00892.20 PSC71321.1 - 0.00011 22.4 35.9 0.048 13.8 17.9 3.7 2 1 2 4 4 4 3 EamA-like transporter family SSXT PF05030.12 PSC71322.1 - 2.4e-18 65.5 2.8 2.6e-18 65.4 2.8 1.0 1 0 0 1 1 1 1 SSXT protein (N-terminal region) MMR_HSR1 PF01926.23 PSC71323.1 - 6.2e-15 55.3 0.0 1.9e-14 53.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 PSC71323.1 - 0.00031 20.1 0.0 0.00049 19.5 0.0 1.3 1 0 0 1 1 1 1 AIG1 family FeoB_N PF02421.18 PSC71323.1 - 0.00032 20.3 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 PSC71323.1 - 0.0043 17.1 0.0 0.041 13.9 0.0 2.3 2 1 0 3 3 3 1 Dynamin family RsgA_GTPase PF03193.16 PSC71323.1 - 0.03 14.2 0.0 0.24 11.3 0.0 2.2 1 1 0 1 1 1 0 RsgA GTPase Xan_ur_permease PF00860.20 PSC71324.1 - 3.7e-58 197.1 35.8 1.3e-37 129.5 13.5 2.1 1 1 1 2 2 2 2 Permease family adh_short PF00106.25 PSC71324.1 - 1.5e-13 50.7 0.0 7.8e-13 48.3 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC71324.1 - 7.7e-09 35.4 0.0 3.5e-08 33.3 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase HTH_Tnp_1 PF01527.20 PSC71324.1 - 0.19 12.1 0.1 0.4 11.0 0.1 1.4 1 0 0 1 1 1 0 Transposase UPF0182 PF03699.13 PSC71324.1 - 0.79 7.8 2.4 1.4 7.0 2.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) Neur_chan_memb PF02932.16 PSC71325.1 - 7.1e-09 36.1 0.2 2.5e-08 34.3 0.2 1.8 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region DUF4134 PF13572.6 PSC71325.1 - 0.089 13.1 6.0 0.15 12.4 2.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4134) DUF2500 PF10694.9 PSC71325.1 - 0.11 13.0 0.1 0.41 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) DUF4131 PF13567.6 PSC71325.1 - 1.7 8.3 7.7 2.8 7.6 6.8 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) ATP-grasp_4 PF13535.6 PSC71326.1 - 1.2e-18 67.2 0.0 7.1e-17 61.5 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp domain ATPgrasp_N PF18130.1 PSC71326.1 - 1.6e-16 60.6 0.0 4.2e-16 59.3 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp N-terminal domain ATPgrasp_Ter PF15632.6 PSC71326.1 - 1.4e-09 37.8 0.5 1.9e-08 34.1 0.5 2.5 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 PSC71326.1 - 1.6e-08 34.8 0.0 2.6e-07 30.8 0.0 2.3 1 1 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 PSC71326.1 - 2.4e-06 27.2 0.0 0.029 13.9 0.0 2.3 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 PSC71326.1 - 4e-06 26.5 0.0 3.4e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 ATP-grasp domain LAL_C2 PF18603.1 PSC71326.1 - 2.7e-05 24.2 0.0 7.6e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 L-amino acid ligase C-terminal domain 2 RimK PF08443.11 PSC71326.1 - 0.0049 16.5 0.0 0.012 15.3 0.0 1.6 2 0 0 2 2 2 1 RimK-like ATP-grasp domain CPSase_L_D2 PF02786.17 PSC71326.1 - 0.0069 15.9 0.0 0.91 9.0 0.0 2.2 1 1 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain GARS_A PF01071.19 PSC71326.1 - 0.027 14.3 0.0 1.5 8.5 0.0 2.8 1 1 0 1 1 1 0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_5 PF13549.6 PSC71326.1 - 0.053 13.0 0.0 0.15 11.5 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain TFIIA PF03153.13 PSC71327.1 - 0.6 10.0 22.1 0.78 9.7 22.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit eIF3_subunit PF08597.10 PSC71327.1 - 2.1 8.2 8.5 2.5 7.9 8.5 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Presenilin PF01080.17 PSC71327.1 - 5.6 5.6 6.6 5.9 5.6 6.6 1.0 1 0 0 1 1 1 0 Presenilin Histone PF00125.24 PSC71329.1 - 2.9e-54 183.0 1.9 3.2e-54 182.8 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 PSC71329.1 - 0.00013 22.5 1.7 0.00016 22.2 1.7 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 PSC71329.1 - 0.00045 20.5 0.0 0.00069 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 PSC71329.1 - 0.00049 20.2 0.5 0.00074 19.6 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 PSC71329.1 - 0.0052 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PSC71329.1 - 0.016 15.3 0.1 0.031 14.3 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Branch PF02485.21 PSC71330.1 - 2.7e-46 158.1 0.0 4e-46 157.5 0.0 1.2 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Apt1 PF10351.9 PSC71330.1 - 0.083 11.7 3.9 0.11 11.3 3.9 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain BUD22 PF09073.10 PSC71330.1 - 0.83 8.9 6.6 1.5 8.0 6.6 1.3 1 0 0 1 1 1 0 BUD22 UvdE PF03851.14 PSC71331.1 - 5.8e-57 193.0 0.0 1.1e-56 192.1 0.0 1.4 1 0 0 1 1 1 1 UV-endonuclease UvdE DUF4517 PF15006.6 PSC71331.1 - 1.6e-09 38.1 0.2 5.5e-08 33.1 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4517) TFIIA PF03153.13 PSC71331.1 - 0.096 12.7 15.2 0.14 12.1 15.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 PSC71331.1 - 0.23 10.4 13.1 12 4.7 13.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) eIF-3_zeta PF05091.12 PSC71331.1 - 2.9 6.7 7.1 4 6.3 7.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 PSC71331.1 - 4.3 6.0 6.1 6 5.5 6.1 1.1 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 PSC71331.1 - 6.5 6.0 10.0 11 5.3 10.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PfkB PF00294.24 PSC71332.1 - 4.1e-39 134.7 5.2 8.7e-23 81.1 0.0 2.3 2 0 0 2 2 2 2 pfkB family carbohydrate kinase SNF2_N PF00176.23 PSC71333.1 - 2.5e-42 144.9 0.0 4.9e-42 143.9 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC71333.1 - 5.4e-16 58.9 0.0 5.2e-13 49.3 0.0 3.1 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Chromo PF00385.24 PSC71333.1 - 5e-14 51.9 0.0 6.7e-09 35.5 0.0 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain zf-HC5HC2H PF13771.6 PSC71333.1 - 8.6e-09 35.5 6.9 8.6e-09 35.5 6.9 3.3 4 0 0 4 4 4 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 PSC71333.1 - 9e-07 29.0 5.7 9e-07 29.0 5.7 2.6 3 1 0 3 3 3 1 PHD-zinc-finger like domain HDA2-3 PF11496.8 PSC71333.1 - 0.0025 17.0 0.1 0.0061 15.8 0.1 1.5 2 0 0 2 2 2 1 Class II histone deacetylase complex subunits 2 and 3 Shugoshin_C PF07557.11 PSC71333.1 - 0.34 10.8 6.7 3.1 7.7 1.1 2.9 2 0 0 2 2 2 0 Shugoshin C terminus DUF410 PF04190.13 PSC71334.1 - 3.9e-34 118.6 0.0 5.1e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF410) DUF4311 PF14188.6 PSC71337.1 - 0.088 12.6 0.2 0.088 12.6 0.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4311) PEPCK_ATP PF01293.20 PSC71338.1 - 5.4e-188 625.4 0.0 6.3e-188 625.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_25 PF13481.6 PSC71338.1 - 0.1 12.2 0.0 1.2 8.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 PSC71338.1 - 0.18 12.0 0.3 1.5 9.0 0.2 2.4 2 0 0 2 2 2 0 AAA domain SAP PF02037.27 PSC71339.1 - 0.088 12.6 0.2 0.47 10.3 0.0 2.4 2 0 0 2 2 2 0 SAP domain EF-hand_7 PF13499.6 PSC71340.1 - 2.3e-13 50.4 2.4 4.1e-07 30.4 0.0 3.5 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 PSC71340.1 - 4.4e-13 47.8 0.2 0.023 14.2 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_5 PF13202.6 PSC71340.1 - 1.2e-10 40.4 1.0 0.017 14.6 0.0 4.0 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 PSC71340.1 - 3.1e-10 39.2 2.9 0.045 13.7 0.0 4.9 5 0 0 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 PSC71340.1 - 3.5e-07 29.9 0.8 0.0096 15.8 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PSC71340.1 - 0.054 13.8 10.9 0.25 11.7 0.2 3.3 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 PSC71340.1 - 0.081 13.1 0.6 0.34 11.1 0.0 2.4 2 1 0 2 2 2 0 Dockerin type I domain AMP-binding PF00501.28 PSC71341.1 - 1.7e-93 313.5 0.0 3.3e-46 157.8 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme ACAS_N PF16177.5 PSC71341.1 - 8.1e-12 44.9 0.0 0.00015 21.6 0.0 2.5 2 0 0 2 2 2 2 Acetyl-coenzyme A synthetase N-terminus PG_binding_1 PF01471.18 PSC71341.1 - 6e-11 42.4 0.9 2.7e-10 40.3 0.9 2.2 1 0 0 1 1 1 1 Putative peptidoglycan binding domain AMP-binding_C PF13193.6 PSC71341.1 - 7.8e-10 39.6 1.7 0.0042 18.0 0.0 4.3 3 0 0 3 3 3 2 AMP-binding enzyme C-terminal domain DUF1967 PF09269.11 PSC71341.1 - 0.016 15.1 0.0 4.5 7.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1967) Prot_ATP_ID_OB PF16450.5 PSC71341.1 - 0.022 14.7 0.9 11 6.1 0.0 3.4 4 0 0 4 4 4 0 Proteasomal ATPase OB C-terminal domain DER1 PF04511.15 PSC71343.1 - 7.5e-28 97.8 5.5 9.8e-28 97.4 5.5 1.1 1 0 0 1 1 1 1 Der1-like family HI0933_like PF03486.14 PSC71344.1 - 4.4e-72 243.0 0.0 6.3e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 HI0933-like protein SEP PF08059.13 PSC71344.1 - 7.4e-20 71.3 0.0 2.1e-19 69.9 0.0 1.8 1 0 0 1 1 1 1 SEP domain RRM_1 PF00076.22 PSC71344.1 - 3.6e-15 55.5 0.0 6.3e-15 54.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UBA_4 PF14555.6 PSC71344.1 - 5.5e-15 54.9 0.1 9.6e-15 54.1 0.1 1.4 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 PSC71344.1 - 4.6e-14 52.4 0.0 8.9e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 UBX domain FAD_binding_2 PF00890.24 PSC71344.1 - 7.2e-11 41.8 1.0 2.9e-10 39.8 0.8 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 PSC71344.1 - 1.8e-07 30.7 0.6 3.8e-06 26.3 0.6 2.1 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PSC71344.1 - 5.6e-06 26.5 0.1 2.3e-05 24.6 0.1 2.2 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 PSC71344.1 - 1.8e-05 24.1 0.9 3.1e-05 23.4 0.9 1.2 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_oxidored PF12831.7 PSC71344.1 - 3.8e-05 23.2 3.7 6.2e-05 22.5 3.7 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 PSC71344.1 - 5.7e-05 22.5 1.1 9.3e-05 21.8 1.1 1.3 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 PSC71344.1 - 5.8e-05 22.4 0.7 0.00013 21.3 0.7 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.6 PSC71344.1 - 0.00079 18.8 0.1 0.046 13.0 0.6 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PSC71344.1 - 0.0037 16.4 2.8 0.0064 15.6 2.8 1.3 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.12 PSC71344.1 - 0.011 14.8 0.4 0.16 11.0 1.0 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 PSC71344.1 - 0.029 14.9 1.2 0.062 13.9 1.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PSC71344.1 - 0.049 13.6 0.3 0.17 11.8 0.3 1.9 1 1 0 1 1 1 0 FAD-NAD(P)-binding 3HCDH_N PF02737.18 PSC71344.1 - 0.17 11.7 1.8 0.28 11.1 1.8 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain PHM7_cyt PF14703.6 PSC71344.1 - 0.2 11.9 0.0 0.35 11.1 0.0 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter RRM_occluded PF16842.5 PSC71344.1 - 0.21 11.5 0.0 0.49 10.3 0.0 1.5 1 0 0 1 1 1 0 Occluded RNA-recognition motif DUF1388 PF07142.12 PSC71344.1 - 9.9 6.2 37.0 0.18 11.8 11.8 3.0 2 1 1 3 3 3 0 Repeat of unknown function (DUF1388) DNA_alkylation PF08713.11 PSC71345.1 - 8.8e-19 68.1 0.0 1.1e-18 67.8 0.0 1.1 1 0 0 1 1 1 1 DNA alkylation repair enzyme SAD_SRA PF02182.17 PSC71346.1 - 8.6e-32 110.0 0.0 2e-31 108.8 0.0 1.6 1 0 0 1 1 1 1 SAD/SRA domain SET PF00856.28 PSC71346.1 - 3e-16 60.3 0.2 1e-14 55.3 0.0 3.3 3 1 0 3 3 3 1 SET domain Pre-SET PF05033.16 PSC71346.1 - 7.8e-06 26.5 2.7 2.6e-05 24.8 0.1 2.8 2 1 0 2 2 2 1 Pre-SET motif F-box-like PF12937.7 PSC71347.1 - 1.6e-05 24.7 0.1 4.4e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 F-box-like DUF3082 PF11282.8 PSC71348.1 - 9.9e-22 77.0 1.1 2.7e-21 75.6 1.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3082) BLOC1S3 PF15753.5 PSC71348.1 - 0.18 11.9 1.2 1.5 9.0 0.1 2.1 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 DUF3149 PF11346.8 PSC71348.1 - 0.23 11.1 0.9 9.8 5.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3149) DAGAT PF03982.13 PSC71349.1 - 8.1e-60 202.2 0.0 1e-59 201.9 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase LRR_4 PF12799.7 PSC71349.1 - 1e-12 48.1 5.6 1.8e-05 25.0 1.1 3.5 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PSC71349.1 - 4.3e-07 29.6 0.0 7.7e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 PSC71349.1 - 1.2e-06 28.2 9.0 0.0086 15.8 1.6 3.5 1 1 1 3 3 3 3 Leucine rich repeat SLAC1 PF03595.17 PSC71350.1 - 1.5e-38 132.9 33.6 1.5e-38 132.9 33.6 1.8 2 0 0 2 2 2 1 Voltage-dependent anion channel DUF4395 PF14340.6 PSC71350.1 - 4.9e-19 69.0 8.4 4.9e-19 69.0 8.4 4.5 3 1 2 5 5 5 2 Domain of unknown function (DUF4395) Hemerythrin PF01814.23 PSC71350.1 - 1e-08 35.9 7.2 1.9e-08 35.0 7.2 1.4 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Glutaredoxin PF00462.24 PSC71350.1 - 2.5e-06 27.6 0.0 7.4e-06 26.1 0.0 1.9 1 0 0 1 1 1 1 Glutaredoxin Diphthami_syn_2 PF01902.17 PSC71351.1 - 2.1e-25 89.5 0.0 4.8e-25 88.3 0.0 1.4 1 1 0 1 1 1 1 Diphthamide synthase Ribonuc_L-PSP PF01042.21 PSC71351.1 - 1.6e-08 34.6 0.3 0.00014 21.9 0.0 3.5 3 0 0 3 3 3 2 Endoribonuclease L-PSP Sel1 PF08238.12 PSC71352.1 - 1.8e-18 66.5 35.5 0.00066 20.3 0.2 10.4 11 0 0 11 11 11 5 Sel1 repeat DUF2722 PF10846.8 PSC71352.1 - 1.2 8.0 32.5 0.12 11.3 21.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) EPL1 PF10513.9 PSC71352.1 - 2.1 8.7 15.3 3.7 7.9 10.8 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like Velvet PF11754.8 PSC71352.1 - 3.4 7.5 11.2 18 5.2 10.3 2.1 2 0 0 2 2 2 0 Velvet factor SLC12 PF03522.15 PSC71352.1 - 3.6 6.5 8.2 7.1 5.5 8.2 1.4 1 0 0 1 1 1 0 Solute carrier family 12 NPR3 PF03666.13 PSC71352.1 - 3.8 6.2 9.8 6 5.5 9.8 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Tim54 PF11711.8 PSC71352.1 - 4.3 6.0 13.3 0.63 8.8 9.2 1.6 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 MDM10 PF12519.8 PSC71352.1 - 5.1 5.8 5.2 8.7 5.1 5.2 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 ALMT PF11744.8 PSC71352.1 - 6.1 5.6 5.8 11 4.7 5.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Peptidase_C48 PF02902.19 PSC71353.1 - 2.1e-08 34.3 0.0 6.5e-06 26.1 0.0 2.8 2 1 0 2 2 2 2 Ulp1 protease family, C-terminal catalytic domain Acyl-CoA_dh_1 PF00441.24 PSC71354.1 - 5.1e-28 98.2 3.0 5.1e-28 98.2 3.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PSC71354.1 - 1.5e-21 77.2 0.8 4.6e-21 75.6 0.0 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 PSC71354.1 - 1.1e-20 73.7 0.0 2.2e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain bZIP_2 PF07716.15 PSC71354.1 - 0.012 15.7 10.2 0.016 15.2 2.0 3.2 2 0 0 2 2 2 0 Basic region leucine zipper DUF3584 PF12128.8 PSC71354.1 - 1 6.8 21.1 1.5 6.2 21.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) KASH_CCD PF14662.6 PSC71354.1 - 1.8 8.4 22.7 1.9 8.3 10.8 2.3 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH RCC1 PF00415.18 PSC71355.1 - 6.1e-45 151.6 22.7 4.8e-11 43.1 0.0 8.3 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PSC71355.1 - 1.5e-23 82.0 43.7 2.5e-06 27.1 1.6 8.1 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.6 PSC71355.1 - 2.3e-06 27.7 1.1 0.00037 20.7 0.1 3.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC71355.1 - 7.8e-06 26.3 0.0 2.1e-05 25.0 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PSC71355.1 - 9.6e-06 26.1 0.0 2.6e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 PSC71355.1 - 1.3e-05 25.4 0.9 0.097 13.2 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeat PAN_4 PF14295.6 PSC71355.1 - 2.6e-05 24.0 5.0 5.2e-05 23.1 5.0 1.5 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 PSC71355.1 - 7.1e-05 22.7 2.1 0.00014 21.8 2.1 1.4 1 0 0 1 1 1 1 PAN domain NifU_N PF01592.16 PSC71357.1 - 8.6e-54 181.1 0.1 1.8e-53 180.1 0.1 1.5 1 0 0 1 1 1 1 NifU-like N terminal domain RCC1 PF00415.18 PSC71357.1 - 5.9e-51 170.9 15.5 5.3e-13 49.4 0.3 7.5 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PSC71357.1 - 5.5e-17 61.1 29.6 2.3e-06 27.3 3.4 7.0 7 1 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat MccV PF17508.2 PSC71357.1 - 0.021 15.4 6.9 0.37 11.3 0.1 3.5 2 1 1 3 3 3 0 Microcin V bacteriocin Ank_4 PF13637.6 PSC71358.1 - 1.3e-23 83.0 3.3 5.5e-08 33.2 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PSC71358.1 - 1e-22 80.5 5.1 1.7e-16 60.6 1.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC71358.1 - 1.9e-15 56.7 5.2 4.2e-10 39.7 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PSC71358.1 - 3.8e-15 55.5 6.9 4.2e-07 30.1 0.1 4.1 4 1 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 PSC71358.1 - 2e-14 52.2 1.1 0.00013 22.1 0.1 4.3 4 1 1 5 5 5 2 Ankyrin repeat Methyltransf_31 PF13847.6 PSC71359.1 - 2.4e-25 89.1 0.0 4.9e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC71359.1 - 4.7e-15 56.1 0.0 1.4e-14 54.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC71359.1 - 1.6e-13 51.1 0.0 4.4e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC71359.1 - 5e-10 39.1 0.0 8.8e-10 38.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 PSC71359.1 - 6.5e-10 39.1 0.0 1.4e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain zf-MYND PF01753.18 PSC71359.1 - 2.1e-09 37.3 16.3 2.1e-09 37.3 16.3 3.1 2 0 0 2 2 2 1 MYND finger Methyltransf_12 PF08242.12 PSC71359.1 - 9.9e-08 32.6 0.0 2.3e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PSC71359.1 - 0.00064 19.5 0.0 0.0012 18.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 PSC71359.1 - 0.036 13.9 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase ORC6 PF05460.13 PSC71359.1 - 5.3 6.2 9.2 0.18 11.1 2.9 1.7 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) Methyltransf_31 PF13847.6 PSC71360.1 - 1.4e-17 63.9 0.0 3e-17 62.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC71360.1 - 5.4e-10 39.8 0.0 1.6e-09 38.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC71360.1 - 1.3e-09 38.6 0.0 3.7e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain zf-MYND PF01753.18 PSC71360.1 - 2e-09 37.3 16.3 2e-09 37.3 16.3 3.1 2 0 0 2 2 1 1 MYND finger Methyltransf_23 PF13489.6 PSC71360.1 - 3.2e-07 30.3 0.0 7.3e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC71360.1 - 7.4e-05 23.4 0.0 0.00018 22.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC71360.1 - 0.00093 18.6 0.0 0.0017 17.8 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.13 PSC71360.1 - 0.0095 15.4 0.0 0.016 14.6 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 PSC71360.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.15 PSC71360.1 - 0.036 13.9 0.0 0.064 13.1 0.0 1.3 1 0 0 1 1 1 0 Hypothetical methyltransferase ORC6 PF05460.13 PSC71360.1 - 5.2 6.2 9.2 0.17 11.1 2.9 1.7 2 0 0 2 2 2 0 Origin recognition complex subunit 6 (ORC6) RCC1 PF00415.18 PSC71361.1 - 1.2e-80 266.0 29.4 8.2e-14 52.0 0.0 8.2 7 1 1 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PSC71361.1 - 2.2e-41 138.8 48.2 2.6e-09 36.6 0.9 7.6 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat Sld5 PF05916.11 PSC71362.1 - 1.5e-16 60.8 0.0 1.9e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 GINS complex protein PCNA_N PF00705.18 PSC71363.1 - 2.8e-53 179.0 1.5 4.4e-53 178.3 1.5 1.3 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 PSC71363.1 - 2.1e-51 173.4 0.0 3.6e-51 172.7 0.0 1.4 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.16 PSC71363.1 - 7.7e-08 31.7 0.2 1.1e-05 24.7 0.2 2.0 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.13 PSC71363.1 - 0.028 13.9 0.0 0.1 12.0 0.0 1.9 1 1 0 1 1 1 0 Rad9 Ribosomal_L2_C PF03947.18 PSC71363.1 - 0.076 13.2 0.0 0.37 11.0 0.0 2.1 1 1 1 2 2 2 0 Ribosomal Proteins L2, C-terminal domain DUF4251 PF14059.6 PSC71363.1 - 0.092 12.7 0.0 0.24 11.3 0.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4251) Mre11_DNA_bind PF04152.14 PSC71365.1 - 3.3e-42 144.7 0.0 3.3e-42 144.7 0.0 2.5 3 0 0 3 3 3 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 PSC71365.1 - 3.9e-13 50.4 0.1 5.8e-13 49.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PSC71365.1 - 6.1e-05 23.3 0.0 0.0021 18.2 0.0 3.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Ndc1_Nup PF09531.10 PSC71365.1 - 1.3 7.6 9.8 2.1 6.9 9.8 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GATA PF00320.27 PSC71366.1 - 2.5e-12 46.2 3.5 5.2e-12 45.2 3.5 1.5 1 0 0 1 1 1 1 GATA zinc finger Hydrolase_6 PF13344.6 PSC71367.1 - 4.1e-32 110.3 0.0 6.9e-32 109.6 0.0 1.4 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PSC71367.1 - 2.8e-19 68.9 0.0 6.7e-19 67.7 0.0 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 PSC71367.1 - 7.4e-11 42.7 0.5 3.9e-10 40.4 0.5 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PSC71367.1 - 1.1e-08 35.4 0.2 9.5e-05 22.6 0.0 2.6 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 PSC71367.1 - 0.00042 20.0 0.0 0.012 15.3 0.0 2.2 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase Sof1 PF04158.14 PSC71368.1 - 2.8e-28 98.0 8.5 5e-28 97.2 8.5 1.4 1 0 0 1 1 1 1 Sof1-like domain WD40 PF00400.32 PSC71368.1 - 1.5e-25 88.9 6.2 2e-05 25.3 0.1 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat F-box-like PF12937.7 PSC71368.1 - 0.0021 17.9 0.0 0.0021 17.9 0.0 3.2 3 0 0 3 3 3 1 F-box-like ANAPC4_WD40 PF12894.7 PSC71368.1 - 0.0029 17.9 0.0 8.1 6.8 0.0 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Trypsin PF00089.26 PSC71369.1 - 6.3e-37 127.5 0.0 9.1e-37 127.0 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PSC71369.1 - 0.00013 22.9 0.0 0.00042 21.3 0.0 1.8 1 1 0 1 1 1 1 Trypsin-like peptidase domain rve PF00665.26 PSC71370.1 - 8.3e-19 67.9 0.0 1.8e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC71370.1 - 0.0066 16.2 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain RRM_1 PF00076.22 PSC71371.1 - 2.1e-47 158.8 0.0 1.5e-15 56.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PSC71371.1 - 4.8e-07 29.4 0.0 0.026 14.1 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PSC71371.1 - 6.1e-07 29.5 0.0 0.25 11.5 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif BRAP2 PF07576.12 PSC71371.1 - 0.0013 18.9 0.0 0.6 10.4 0.0 2.9 3 0 0 3 3 3 2 BRCA1-associated protein 2 Sugar_tr PF00083.24 PSC71372.1 - 5.7e-73 246.3 20.0 5.5e-71 239.8 15.9 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter rve PF00665.26 PSC71372.1 - 9.6e-19 67.7 0.0 2.1e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC71372.1 - 0.0084 15.9 0.0 0.022 14.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DUF983 PF06170.12 PSC71372.1 - 0.72 10.3 7.4 0.73 10.3 1.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF983) HMG_box PF00505.19 PSC71373.1 - 4.3e-22 78.3 0.6 9.1e-22 77.3 0.6 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box POB3_N PF17292.2 PSC71373.1 - 4e-21 75.2 0.1 3.3e-18 65.9 0.0 2.7 2 0 0 2 2 2 2 POB3-like N-terminal PH domain Rtt106 PF08512.12 PSC71373.1 - 1.2e-20 73.7 0.0 2.7e-20 72.6 0.0 1.6 2 0 0 2 2 2 1 Histone chaperone Rttp106-like SSrecog PF03531.14 PSC71373.1 - 4.6e-20 71.3 0.1 1.2e-19 69.9 0.0 1.8 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) HMG_box_2 PF09011.10 PSC71373.1 - 4.3e-17 62.5 1.0 9.2e-17 61.4 1.0 1.6 1 0 0 1 1 1 1 HMG-box domain YL1 PF05764.13 PSC71373.1 - 0.00047 20.3 16.4 0.00091 19.4 16.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein YABBY PF04690.13 PSC71373.1 - 0.027 15.0 1.7 0.05 14.2 1.7 1.4 1 0 0 1 1 1 0 YABBY protein Merozoite_SPAM PF07133.11 PSC71373.1 - 0.4 10.6 12.6 1 9.3 12.6 1.6 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.14 PSC71373.1 - 1 7.6 10.8 1.5 7.0 10.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Nop16 PF09420.10 PSC71374.1 - 1.3e-20 74.4 1.3 8.2e-14 52.1 0.1 2.0 1 1 1 2 2 2 2 Ribosome biogenesis protein Nop16 MR_MLE_C PF13378.6 PSC71374.1 - 0.01 15.4 0.8 0.012 15.2 0.8 1.3 1 0 0 1 1 1 0 Enolase C-terminal domain-like GGDEF_2 PF17853.1 PSC71375.1 - 0.04 14.2 0.6 0.04 14.2 0.6 2.0 2 1 0 2 2 2 0 GGDEF-like domain RRM_1 PF00076.22 PSC71376.1 - 5.9e-22 77.3 0.0 1.2e-09 37.8 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PSC71376.1 - 0.00088 19.2 0.0 0.66 10.0 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 PSC71376.1 - 0.0088 15.9 0.0 0.98 9.3 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif PHM7_cyt PF14703.6 PSC71376.1 - 0.1 12.8 0.1 26 5.0 0.0 3.2 2 2 2 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter Glyco_hydro_9 PF00759.19 PSC71377.1 - 4.9e-112 375.4 4.1 5.6e-112 375.2 4.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glutaredoxin PF00462.24 PSC71379.1 - 7.3e-20 70.9 0.0 1.2e-19 70.3 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin OB_NTP_bind PF07717.16 PSC71380.1 - 9e-18 64.4 0.0 1.6e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 PSC71380.1 - 8.5e-16 58.2 1.1 4.1e-15 56.0 0.0 2.5 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 PSC71380.1 - 1.4e-15 57.5 0.0 3.1e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.22 PSC71380.1 - 6.5e-09 36.1 0.0 3.2e-08 33.8 0.0 2.1 1 1 0 1 1 1 1 RWD domain DEAD PF00270.29 PSC71380.1 - 4.9e-05 23.2 0.0 0.0002 21.2 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase dsrm PF00035.26 PSC71380.1 - 0.0014 19.2 0.0 0.0042 17.8 0.0 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif zf-C2HC_2 PF13913.6 PSC71380.1 - 0.0021 17.9 2.1 0.11 12.4 0.5 2.5 2 0 0 2 2 2 1 zinc-finger of a C2HC-type zf-C2H2_4 PF13894.6 PSC71380.1 - 0.0042 17.8 2.0 0.0079 16.9 1.0 2.1 2 0 0 2 2 1 1 C2H2-type zinc finger DND1_DSRM PF14709.7 PSC71380.1 - 0.0053 17.0 0.1 0.0053 17.0 0.1 2.8 3 0 0 3 3 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 zf-C2H2 PF00096.26 PSC71380.1 - 0.0088 16.5 1.0 0.0088 16.5 1.0 2.0 2 0 0 2 2 1 1 Zinc finger, C2H2 type zf-Di19 PF05605.12 PSC71380.1 - 0.0093 16.2 0.3 0.022 15.0 0.3 1.6 1 0 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding ATPase PF06745.13 PSC71380.1 - 0.019 14.3 0.1 0.05 12.9 0.1 1.7 1 0 0 1 1 1 0 KaiC DUF4770 PF15994.5 PSC71380.1 - 0.021 15.1 0.6 0.037 14.3 0.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) AAA_22 PF13401.6 PSC71380.1 - 0.094 13.0 0.0 0.29 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 PSC71380.1 - 0.11 11.5 0.0 0.21 10.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_31 PF13614.6 PSC71382.1 - 1e-15 58.1 0.0 3.2e-15 56.5 0.0 1.8 1 1 0 1 1 1 1 AAA domain CbiA PF01656.23 PSC71382.1 - 1.6e-07 31.4 0.0 4.6e-07 29.9 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 PSC71382.1 - 0.088 12.3 0.2 0.29 10.6 0.0 1.8 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ ArsA_ATPase PF02374.15 PSC71382.1 - 0.2 10.8 0.0 0.57 9.3 0.0 1.7 1 1 0 1 1 1 0 Anion-transporting ATPase MRP-L28 PF09812.9 PSC71383.1 - 4.1e-05 23.8 0.3 5.2e-05 23.4 0.3 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L28 Glyco_tranf_2_3 PF13641.6 PSC71384.1 - 5.5e-26 91.9 0.1 7.7e-26 91.4 0.1 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 PSC71384.1 - 5.6e-19 68.8 3.6 5.6e-19 68.8 3.6 2.0 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glycos_transf_2 PF00535.26 PSC71384.1 - 2.1e-13 50.4 0.0 3.8e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 PSC71384.1 - 3.3e-09 36.4 0.0 6.7e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 EGF_CA PF07645.15 PSC71385.1 - 0.0023 18.1 9.5 0.0023 18.1 9.5 6.5 6 1 1 7 7 7 2 Calcium-binding EGF domain cEGF PF12662.7 PSC71385.1 - 0.0059 16.5 2.6 0.0059 16.5 2.6 6.6 6 0 0 6 6 6 2 Complement Clr-like EGF-like DUF455 PF04305.14 PSC71386.1 - 9.1e-79 264.5 0.3 1.2e-67 228.1 0.1 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF455) G-patch PF01585.23 PSC71387.1 - 1.8e-13 50.1 3.0 1.8e-13 50.1 3.0 2.2 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 PSC71387.1 - 8.4e-05 22.6 1.7 0.00019 21.5 0.8 2.2 2 0 0 2 2 2 1 G-patch domain BSP_II PF05432.11 PSC71387.1 - 1.1 8.9 10.9 0.15 11.7 1.3 2.5 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) HGTP_anticodon2 PF12745.7 PSC71387.1 - 1.2 8.6 10.5 0.69 9.4 2.2 2.3 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs AAA PF00004.29 PSC71389.1 - 2.9e-43 147.5 0.0 2.4e-39 134.8 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PSC71389.1 - 7.6e-11 41.6 0.2 7.5e-10 38.5 0.1 2.7 2 0 0 2 2 2 1 AAA+ lid domain Bystin PF05291.11 PSC71389.1 - 3.6e-09 36.3 0.0 1.3e-08 34.5 0.0 1.9 2 0 0 2 2 2 1 Bystin IstB_IS21 PF01695.17 PSC71389.1 - 1.2e-08 34.9 0.0 2e-06 27.7 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_16 PF13191.6 PSC71389.1 - 1.1e-06 29.1 0.0 1.1e-06 29.1 0.0 6.2 7 1 0 7 7 4 1 AAA ATPase domain Bromodomain PF00439.25 PSC71389.1 - 7.5e-06 25.9 0.0 1.6e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 Bromodomain AAA_2 PF07724.14 PSC71389.1 - 9e-06 25.9 0.0 2.3e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 PSC71389.1 - 0.0002 21.4 0.0 0.00091 19.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PSC71389.1 - 0.0031 17.8 0.8 0.21 11.8 0.3 3.6 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.6 PSC71389.1 - 0.0039 17.7 0.0 0.024 15.2 0.0 2.5 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 PSC71389.1 - 0.018 15.4 0.0 0.059 13.8 0.0 1.9 2 0 0 2 2 1 0 RNA helicase RuvB_N PF05496.12 PSC71389.1 - 0.018 14.8 0.1 0.19 11.5 0.0 2.5 2 1 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 PSC71389.1 - 0.033 13.4 0.0 0.059 12.6 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Mg_chelatase PF01078.21 PSC71389.1 - 0.057 12.8 0.2 0.14 11.5 0.0 1.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 PSC71389.1 - 0.062 13.5 0.0 0.062 13.5 0.0 4.8 5 0 0 5 5 4 0 AAA domain Sigma54_activ_2 PF14532.6 PSC71389.1 - 0.093 12.8 0.0 0.26 11.4 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 PSC71389.1 - 0.11 11.9 0.0 0.32 10.4 0.0 1.7 1 0 0 1 1 1 0 PhoH-like protein AAA_33 PF13671.6 PSC71389.1 - 0.17 12.0 0.0 0.17 12.0 0.0 4.6 7 0 0 7 7 2 0 AAA domain AAA_14 PF13173.6 PSC71389.1 - 0.18 11.8 0.0 0.37 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain DAP_epimerase PF01678.19 PSC71389.1 - 0.2 11.8 1.5 0.26 11.5 0.1 1.9 2 0 0 2 2 1 0 Diaminopimelate epimerase RRP7 PF12923.7 PSC71390.1 - 1.7e-17 63.7 0.6 1.7e-17 63.7 0.6 2.1 2 1 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain RRM_Rrp7 PF17799.1 PSC71390.1 - 0.00079 19.3 0.0 0.0015 18.4 0.0 1.4 1 0 0 1 1 1 1 Rrp7 RRM-like N-terminal domain Amidohydro_1 PF01979.20 PSC71391.1 - 1.3e-30 106.9 0.0 2.1e-30 106.2 0.0 1.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 PSC71391.1 - 3.1e-14 53.3 2.0 5.1e-08 32.8 0.0 3.4 2 1 1 4 4 4 2 Amidohydrolase family Brix PF04427.18 PSC71392.1 - 1.7e-30 106.5 0.6 2.7e-30 105.9 0.6 1.3 1 0 0 1 1 1 1 Brix domain PNP_UDP_1 PF01048.20 PSC71392.1 - 1.5e-26 93.1 1.6 1.5e-26 93.1 1.6 2.0 2 0 0 2 2 2 1 Phosphorylase superfamily CBM_20 PF00686.19 PSC71392.1 - 5.3e-12 45.5 0.0 1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain CENP-F_leu_zip PF10473.9 PSC71392.1 - 0.96 9.5 19.1 0.02 14.9 6.7 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Brix PF04427.18 PSC71393.1 - 1.7e-30 106.5 0.6 2.7e-30 105.9 0.6 1.3 1 0 0 1 1 1 1 Brix domain PNP_UDP_1 PF01048.20 PSC71393.1 - 1.5e-26 93.1 1.6 1.5e-26 93.1 1.6 2.0 2 0 0 2 2 2 1 Phosphorylase superfamily CBM_20 PF00686.19 PSC71393.1 - 5.3e-12 45.5 0.0 1e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain CENP-F_leu_zip PF10473.9 PSC71393.1 - 1.6 8.8 19.8 0.019 15.0 6.7 3.2 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 RimM PF01782.18 PSC71394.1 - 6.5e-18 64.7 0.0 1.1e-17 64.0 0.0 1.4 1 0 0 1 1 1 1 RimM N-terminal domain PRC PF05239.16 PSC71394.1 - 4.5e-11 42.7 0.0 2.5e-06 27.4 0.0 2.4 2 0 0 2 2 2 2 PRC-barrel domain GRP PF07172.11 PSC71394.1 - 0.0031 18.2 6.7 0.0053 17.4 6.7 1.3 1 0 0 1 1 1 1 Glycine rich protein family Ribosomal_60s PF00428.19 PSC71394.1 - 0.025 15.2 6.3 0.025 15.2 6.3 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Ndc1_Nup PF09531.10 PSC71395.1 - 0.12 11.0 0.0 0.15 10.8 0.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PRODH PF18327.1 PSC71395.1 - 0.16 12.2 3.4 0.39 11.0 0.9 2.4 2 0 0 2 2 2 0 Proline utilization A proline dehydrogenase N-terminal domain FeThRed_B PF02943.15 PSC71396.1 - 8.2e-42 141.5 3.1 1e-41 141.2 3.1 1.1 1 0 0 1 1 1 1 Ferredoxin thioredoxin reductase catalytic beta chain MMR_HSR1 PF01926.23 PSC71397.1 - 2.4e-09 37.3 0.0 1.7e-08 34.6 0.0 2.2 1 1 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PSC71397.1 - 1.4e-06 28.4 0.0 1.5e-05 25.1 0.0 2.2 2 0 0 2 2 2 1 Dynamin family RsgA_GTPase PF03193.16 PSC71397.1 - 0.00047 20.1 0.0 0.00088 19.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase FeoB_N PF02421.18 PSC71397.1 - 0.13 11.8 0.0 0.86 9.1 0.0 2.3 3 0 0 3 3 3 0 Ferrous iron transport protein B Pkinase PF00069.25 PSC71399.1 - 2e-44 151.9 0.0 5.6e-44 150.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC71399.1 - 2e-25 89.5 0.0 3.4e-25 88.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Glutaredoxin PF00462.24 PSC71399.1 - 5.7e-12 45.7 2.4 1.2e-11 44.7 2.4 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 PSC71399.1 - 6.6e-11 42.5 0.1 1.5e-10 41.3 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 PSC71399.1 - 2.2e-08 34.8 0.0 3.3e-07 31.0 0.0 2.4 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 PSC71399.1 - 2.4e-06 27.7 0.1 5.2e-06 26.7 0.1 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Pkinase_fungal PF17667.1 PSC71399.1 - 2.4e-06 26.6 0.1 3.9e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PSC71399.1 - 8.1e-06 25.4 0.0 0.0023 17.3 0.0 2.7 2 1 0 2 2 2 1 Kinase-like GST_N PF02798.20 PSC71399.1 - 0.0033 17.7 0.0 0.0062 16.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain APH PF01636.23 PSC71399.1 - 0.0046 16.9 10.0 0.21 11.5 0.2 3.7 2 2 1 3 3 2 2 Phosphotransferase enzyme family GST_C_2 PF13410.6 PSC71399.1 - 0.065 13.3 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Hydrolase PF00702.26 PSC71400.1 - 0.00011 22.6 0.0 0.00014 22.2 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PSC71400.1 - 0.00021 21.5 0.0 0.00027 21.1 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PSC71400.1 - 0.035 14.2 0.0 0.061 13.4 0.0 1.3 1 0 0 1 1 1 0 HAD-hyrolase-like ARGLU PF15346.6 PSC71401.1 - 7.8e-12 45.3 49.8 7.8e-12 45.3 49.8 1.6 1 1 1 2 2 2 1 Arginine and glutamate-rich 1 Caldesmon PF02029.15 PSC71401.1 - 0.72 8.5 45.0 1.3 7.7 45.0 1.4 1 0 0 1 1 1 0 Caldesmon TFIIA PF03153.13 PSC71401.1 - 9.6 6.1 17.5 11 5.8 17.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Dor1 PF04124.12 PSC71402.1 - 3.8e-92 308.6 0.0 4.5e-92 308.3 0.0 1.0 1 0 0 1 1 1 1 Dor1-like family Vps51 PF08700.11 PSC71402.1 - 3.4e-06 27.1 0.0 6.8e-06 26.1 0.0 1.5 1 0 0 1 1 1 1 Vps51/Vps67 Vps54_N PF10475.9 PSC71402.1 - 0.005 16.2 0.0 0.007 15.7 0.0 1.1 1 0 0 1 1 1 1 Vacuolar-sorting protein 54, of GARP complex PPR PF01535.20 PSC71402.1 - 0.17 12.2 0.0 0.4 11.0 0.0 1.6 1 0 0 1 1 1 0 PPR repeat ADIP PF11559.8 PSC71402.1 - 0.17 12.0 0.5 0.42 10.7 0.5 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding RPAP3_C PF13877.6 PSC71402.1 - 0.21 12.1 0.1 4.7 7.8 0.0 2.6 3 0 0 3 3 3 0 Potential Monad-binding region of RPAP3 PH PF00169.29 PSC71403.1 - 5.2e-09 36.6 0.0 7.9e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 PSC71403.1 - 3.2e-05 24.3 0.0 5.5e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain PH_8 PF15409.6 PSC71403.1 - 0.0022 18.2 0.0 0.0039 17.4 0.0 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain DUF4614 PF15391.6 PSC71403.1 - 5.9 6.8 5.7 0.79 9.7 1.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4614) EMC1_C PF07774.13 PSC71404.1 - 1.2e-54 185.3 0.0 1.9e-54 184.6 0.0 1.3 1 0 0 1 1 1 1 ER membrane protein complex subunit 1, C-terminal PQQ_2 PF13360.6 PSC71404.1 - 1.4e-11 44.5 20.4 5.6e-05 22.8 0.1 4.3 4 1 1 5 5 5 3 PQQ-like domain PQQ PF01011.21 PSC71404.1 - 0.0026 17.6 4.6 5.4 7.1 0.2 4.9 5 0 0 5 5 5 2 PQQ enzyme repeat PQQ_3 PF13570.6 PSC71404.1 - 7.3 7.2 19.5 19 5.9 1.3 6.4 6 0 0 6 6 6 0 PQQ-like domain Lactamase_B_2 PF12706.7 PSC71405.1 - 1.1e-11 44.6 0.0 6.4e-10 38.9 0.3 2.9 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 PSC71405.1 - 1.1e-11 44.2 0.0 2.8e-11 42.9 0.0 1.7 1 0 0 1 1 1 1 tRNase Z endonuclease V_ATPase_prox PF18274.1 PSC71405.1 - 0.035 14.1 0.9 0.066 13.2 0.1 1.9 2 0 0 2 2 2 0 Vacuolar ATPase Subunit I N-terminal proximal lobe Lactamase_B PF00753.27 PSC71405.1 - 0.14 12.2 3.6 0.61 10.1 0.6 2.8 3 0 0 3 3 3 0 Metallo-beta-lactamase superfamily KH_1 PF00013.29 PSC71406.1 - 1.7e-05 24.6 0.0 3.4e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 PSC71406.1 - 0.047 13.5 0.1 0.095 12.5 0.1 1.4 1 0 0 1 1 1 0 KH domain GRP PF07172.11 PSC71406.1 - 1 10.1 10.7 4.2 8.1 10.7 2.0 1 0 0 1 1 1 0 Glycine rich protein family RRM_1 PF00076.22 PSC71407.1 - 5.6e-23 80.6 0.0 1.6e-12 47.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TFIIA PF03153.13 PSC71407.1 - 0.0029 17.7 29.5 0.0044 17.1 29.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 PSC71407.1 - 0.021 15.0 0.8 0.036 14.2 0.8 1.3 1 0 0 1 1 1 0 DDHD domain V_ATPase_I PF01496.19 PSC71407.1 - 0.067 11.1 2.8 0.09 10.7 2.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nup35_RRM_2 PF14605.6 PSC71407.1 - 0.13 12.3 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Activator_LAG-3 PF11498.8 PSC71407.1 - 0.18 10.7 33.9 0.29 10.1 33.9 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF4407 PF14362.6 PSC71407.1 - 0.75 9.1 9.0 1.9 7.8 9.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Selenoprotein_S PF06936.11 PSC71407.1 - 1.7 8.4 20.8 4.8 6.9 20.8 1.8 1 0 0 1 1 1 0 Selenoprotein S (SelS) VIR_N PF15912.5 PSC71407.1 - 4.7 6.7 9.7 8.1 5.9 9.7 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal DUF2052 PF09747.9 PSC71407.1 - 6.5 6.8 18.8 8.4 6.5 15.6 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) EF-hand_7 PF13499.6 PSC71408.1 - 6.8e-06 26.5 0.0 0.00015 22.2 0.0 3.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PSC71408.1 - 1.5e-05 24.6 0.0 0.031 14.2 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 PSC71408.1 - 0.00038 19.8 0.0 0.0044 16.5 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 PSC71408.1 - 0.00079 18.8 0.1 0.0018 17.7 0.1 1.6 1 0 0 1 1 1 1 EF hand DUF2935 PF11155.8 PSC71408.1 - 0.011 16.1 0.0 0.65 10.3 0.0 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF2935) EF-hand_8 PF13833.6 PSC71408.1 - 0.016 15.1 0.0 0.069 13.0 0.0 2.1 1 0 0 1 1 1 0 EF-hand domain pair zf_C2H2_ZHX PF18387.1 PSC71408.1 - 1.6 8.4 4.3 1.1 9.0 0.4 2.4 2 0 0 2 2 2 0 Zinc-fingers and homeoboxes C2H2 finger domain PGM_PMM_I PF02878.16 PSC71409.1 - 1.4e-31 109.0 0.0 2.5e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 PSC71409.1 - 1.5e-29 102.5 0.0 3.7e-29 101.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 PSC71409.1 - 2.7e-12 47.2 0.0 5.5e-12 46.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 PSC71409.1 - 6.9e-07 29.3 0.0 1.7e-06 28.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DnaJ PF00226.31 PSC71410.1 - 4.6e-12 45.9 0.0 9.8e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain SAPS PF04499.15 PSC71410.1 - 1.2 7.9 5.8 1.8 7.2 5.8 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF4407 PF14362.6 PSC71410.1 - 2.9 7.2 30.7 0.98 8.7 11.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FAM101 PF15068.6 PSC71410.1 - 3.1 7.7 5.2 0.86 9.5 0.6 2.3 2 1 1 3 3 3 0 FAM101 family F-box-like PF12937.7 PSC71411.1 - 1.7e-05 24.6 0.9 3.5e-05 23.6 0.9 1.5 1 0 0 1 1 1 1 F-box-like PP2 PF14299.6 PSC71411.1 - 0.00053 20.0 0.0 0.0011 19.1 0.0 1.6 1 1 0 1 1 1 1 Phloem protein 2 F-box PF00646.33 PSC71411.1 - 0.097 12.6 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 F-box domain CbeA_antitoxin PF06154.11 PSC71411.1 - 0.12 13.0 0.0 0.24 12.0 0.0 1.4 1 0 0 1 1 1 0 CbeA_antitoxin, type IV, cytoskeleton bundling-enhancing factor A T5orf172 PF10544.9 PSC71412.1 - 3.8e-06 27.4 0.0 7.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 T5orf172 domain DUF3586 PF12131.8 PSC71412.1 - 0.08 13.2 1.1 0.16 12.2 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3586) DAHP_synth_2 PF01474.16 PSC71413.1 - 2.5e-193 642.5 0.0 2.9e-193 642.3 0.0 1.0 1 0 0 1 1 1 1 Class-II DAHP synthetase family TFIIA PF03153.13 PSC71414.1 - 0.042 13.9 40.4 0.072 13.1 40.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 PSC71414.1 - 0.14 12.3 0.0 0.14 12.3 0.0 5.0 2 1 2 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 PAT1 PF09770.9 PSC71414.1 - 3.1 6.0 26.5 4.3 5.5 26.5 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PIN_4 PF13638.6 PSC71415.1 - 1.6e-18 67.2 0.0 1.6e-18 67.2 0.0 3.2 4 0 0 4 4 4 1 PIN domain GYF PF02213.16 PSC71415.1 - 0.072 12.8 0.6 0.14 11.9 0.6 1.5 1 0 0 1 1 1 0 GYF domain HTH_28 PF13518.6 PSC71415.1 - 0.17 12.0 2.4 0.5 10.5 0.1 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain Cry1Ac_D5 PF17997.1 PSC71416.1 - 0.15 11.9 0.0 0.2 11.5 0.0 1.1 1 0 0 1 1 1 0 Insecticidal delta-endotoxin CryIA(c) domain 5 Yip1 PF04893.17 PSC71417.1 - 5.4e-10 39.3 11.8 8.9e-10 38.5 11.8 1.4 1 0 0 1 1 1 1 Yip1 domain Aminotran_4 PF01063.19 PSC71418.1 - 2.1e-12 47.4 0.0 2.4e-11 43.9 0.0 2.4 1 1 0 1 1 1 1 Amino-transferase class IV NAD_binding_8 PF13450.6 PSC71418.1 - 0.018 15.3 0.1 0.051 13.8 0.1 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Glyco_transf_22 PF03901.17 PSC71419.1 - 2.5e-54 185.1 0.0 3.5e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Ocnus PF05005.15 PSC71419.1 - 0.00011 22.3 0.0 0.0003 20.9 0.0 1.8 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) DUF1917 PF08939.10 PSC71420.1 - 5.1e-21 75.8 9.4 1.3e-11 45.0 0.2 2.9 1 1 2 3 3 3 2 Domain of unknown function (DUF1917) ZZ PF00569.17 PSC71420.1 - 1.2e-09 37.8 2.2 2.2e-09 37.0 2.2 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type TFIIA PF03153.13 PSC71420.1 - 0.083 12.9 13.6 0.12 12.3 13.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit C1_2 PF03107.16 PSC71420.1 - 0.21 11.9 4.0 0.39 11.1 4.0 1.4 1 0 0 1 1 1 0 C1 domain SNARE PF05739.19 PSC71421.1 - 7.1e-11 41.9 0.4 1.4e-10 41.0 0.4 1.5 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 PSC71421.1 - 1.6e-06 28.0 2.8 1.7e-06 27.9 0.7 2.1 2 1 0 2 2 2 1 Syntaxin Syntaxin_2 PF14523.6 PSC71421.1 - 1.7e-05 25.1 0.1 0.00053 20.3 0.0 2.4 2 1 0 2 2 2 1 Syntaxin-like protein Synaptobrevin PF00957.21 PSC71421.1 - 0.021 14.6 1.0 0.038 13.8 0.1 2.0 2 0 0 2 2 2 0 Synaptobrevin XhlA PF10779.9 PSC71421.1 - 0.096 12.9 1.6 0.5 10.6 1.6 2.2 1 1 0 1 1 1 0 Haemolysin XhlA Baculo_11_kDa PF06143.11 PSC71421.1 - 0.11 12.0 0.0 0.26 10.9 0.0 1.7 1 0 0 1 1 1 0 Baculovirus 11 kDa family GDWWSH PF15667.5 PSC71421.1 - 0.15 11.4 0.5 0.21 11.0 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function with motif GDWWSH Abhydro_lipase PF04083.16 PSC71422.1 - 9.9e-14 50.7 0.0 1.7e-13 49.9 0.0 1.4 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Lipase_3 PF01764.25 PSC71422.1 - 0.15 11.9 0.0 0.28 11.1 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Ank_4 PF13637.6 PSC71423.1 - 6.9e-32 109.4 8.1 9.8e-10 38.8 0.1 4.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 PSC71423.1 - 2.4e-30 104.9 9.9 2e-10 41.1 0.2 3.7 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC71423.1 - 2.1e-19 69.3 3.7 1.3e-06 28.5 0.1 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PSC71423.1 - 3.3e-19 68.4 12.2 0.00013 22.2 0.1 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 PSC71423.1 - 1.1e-15 56.1 3.3 0.013 15.9 0.0 5.8 6 0 0 6 6 6 4 Ankyrin repeat GIDE PF12483.8 PSC71423.1 - 7e-11 41.8 0.2 1.8e-09 37.2 0.2 2.2 1 1 0 1 1 1 1 E3 Ubiquitin ligase DUF747 PF05346.11 PSC71424.1 - 2.9e-65 220.8 0.0 4.2e-65 220.3 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic membrane protein family Pkinase PF00069.25 PSC71424.1 - 5.6e-45 153.8 0.0 8.2e-45 153.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC71424.1 - 6.7e-25 87.8 0.0 1e-24 87.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PSC71424.1 - 0.0023 17.3 0.0 0.0052 16.2 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PSC71424.1 - 0.56 10.1 12.6 0.023 14.6 0.5 3.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family MAPEG PF01124.18 PSC71425.1 - 1.9e-20 73.1 1.1 2.4e-20 72.7 1.1 1.1 1 0 0 1 1 1 1 MAPEG family Ofd1_CTDD PF10637.9 PSC71426.1 - 3.1e-63 213.5 0.0 5.1e-60 203.0 0.0 2.3 2 0 0 2 2 2 2 Oxoglutarate and iron-dependent oxygenase degradation C-term 2OG-FeII_Oxy_4 PF13661.6 PSC71426.1 - 2.6e-25 88.9 0.0 7.5e-25 87.4 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 PSC71426.1 - 8.9e-15 55.4 0.0 2.9e-14 53.7 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ATP12 PF07542.11 PSC71427.1 - 1.4e-29 102.7 0.1 2e-29 102.3 0.1 1.2 1 0 0 1 1 1 1 ATP12 chaperone protein WD40 PF00400.32 PSC71428.1 - 3.5e-24 84.6 11.6 0.0018 19.0 0.2 12.6 14 0 0 14 14 14 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC71428.1 - 4.8e-18 65.2 0.0 0.0019 18.4 0.0 8.7 8 2 1 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain DUF667 PF05018.13 PSC71428.1 - 1.3e-14 54.4 0.0 2.5e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF667) PQQ_2 PF13360.6 PSC71428.1 - 0.0042 16.7 12.8 2 8.0 0.3 5.5 3 2 0 4 4 4 3 PQQ-like domain Ge1_WD40 PF16529.5 PSC71428.1 - 0.035 13.1 0.0 2.3 7.1 0.0 3.4 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 PSC71428.1 - 0.05 12.9 0.0 1 8.6 0.0 3.1 3 0 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal KDZ PF18758.1 PSC71430.1 - 1.8e-25 89.9 0.5 4e-25 88.7 0.4 1.7 1 1 1 2 2 2 1 Kyakuja-Dileera-Zisupton transposase Sigma54_CBD PF04963.13 PSC71430.1 - 0.57 10.0 2.0 0.86 9.4 0.1 2.2 3 0 0 3 3 3 0 Sigma-54 factor, core binding domain Cnd3 PF12719.7 PSC71431.1 - 2.3e-32 112.4 0.0 2.1e-31 109.2 0.0 2.3 2 0 0 2 2 2 1 Nuclear condensing complex subunits, C-term domain TPR_1 PF00515.28 PSC71431.1 - 4.2e-13 48.5 3.6 5.4e-08 32.3 0.0 4.6 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 PSC71431.1 - 2.8e-12 45.8 11.4 2.3e-05 24.2 0.0 6.0 5 1 0 5 5 5 2 Tetratricopeptide repeat HEAT_2 PF13646.6 PSC71431.1 - 6.3e-09 36.1 17.9 9.9e-05 22.7 0.2 5.9 5 0 0 5 5 4 2 HEAT repeats TPR_11 PF13414.6 PSC71431.1 - 9.2e-08 31.7 0.2 0.036 13.8 0.0 4.0 2 1 1 3 3 3 2 TPR repeat HEAT PF02985.22 PSC71431.1 - 4e-07 29.7 15.7 0.21 11.9 0.1 7.3 7 0 0 7 7 7 3 HEAT repeat TPR_12 PF13424.6 PSC71431.1 - 4.3e-07 30.1 20.8 0.0001 22.5 0.2 6.7 4 2 2 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 PSC71431.1 - 1.3e-06 28.4 7.4 4.5e-05 23.5 0.8 5.0 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 PSC71431.1 - 3.1e-06 27.7 14.8 0.00013 22.6 1.9 7.3 6 1 1 7 7 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 PSC71431.1 - 6.1e-06 26.0 0.0 0.0005 20.1 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat Cnd1 PF12717.7 PSC71431.1 - 7.4e-06 26.1 0.1 0.017 15.2 0.0 3.4 2 1 2 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 PSC71431.1 - 1.7e-05 25.2 12.5 0.0075 16.8 0.0 6.5 5 0 0 5 5 5 2 HEAT-like repeat TPR_10 PF13374.6 PSC71431.1 - 0.00048 19.9 0.1 0.00048 19.9 0.1 5.2 5 1 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 PSC71431.1 - 0.0011 19.4 2.3 0.0011 19.4 2.3 4.6 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 PSC71431.1 - 0.01 16.2 2.0 1.7 9.2 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 PSC71431.1 - 0.014 15.4 0.0 0.014 15.4 0.0 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat Ran_BP1 PF00638.18 PSC71433.1 - 0.0054 17.0 0.0 0.0087 16.3 0.0 1.3 1 0 0 1 1 1 1 RanBP1 domain Sporozoite_P67 PF05642.11 PSC71433.1 - 1.1 7.2 11.5 1.4 6.9 11.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen NUDIX PF00293.28 PSC71434.1 - 1.9e-20 73.2 0.1 2.4e-20 72.9 0.1 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 PSC71434.1 - 4e-05 23.6 0.0 6.3e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Methyltransf_14 PF08484.11 PSC71435.1 - 0.015 15.1 0.5 1.3 8.8 0.1 2.1 2 0 0 2 2 2 0 C-methyltransferase C-terminal domain Kinesin PF00225.23 PSC71436.1 - 2.4e-103 345.6 0.0 4.7e-103 344.6 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PSC71436.1 - 2.6e-58 196.2 0.0 8.5e-57 191.3 0.0 2.4 2 0 0 2 2 2 1 Microtubule binding CALCOCO1 PF07888.11 PSC71436.1 - 0.0029 16.5 51.7 0.041 12.8 14.8 3.1 1 1 2 3 3 3 2 Calcium binding and coiled-coil domain (CALCOCO1) like ATG16 PF08614.11 PSC71436.1 - 0.0054 17.0 10.6 0.0054 17.0 10.6 4.3 2 1 1 4 4 4 2 Autophagy protein 16 (ATG16) XhlA PF10779.9 PSC71436.1 - 0.043 14.0 6.8 0.076 13.2 0.9 3.4 2 1 1 3 3 3 0 Haemolysin XhlA Fez1 PF06818.15 PSC71436.1 - 0.069 13.6 41.5 0.99 9.8 14.8 3.6 1 1 2 3 3 3 0 Fez1 CENP-F_leu_zip PF10473.9 PSC71436.1 - 0.13 12.2 44.6 0.28 11.2 8.2 3.7 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATPase_2 PF01637.18 PSC71436.1 - 0.18 11.7 1.2 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Cnn_1N PF07989.11 PSC71436.1 - 0.34 11.1 23.4 8 6.7 2.3 5.1 3 1 1 4 4 4 0 Centrosomin N-terminal motif 1 TMF_TATA_bd PF12325.8 PSC71436.1 - 0.39 10.9 36.5 1.1 9.5 3.4 5.0 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding DUF5082 PF16888.5 PSC71436.1 - 0.42 10.9 29.5 3.1 8.1 6.5 4.5 2 2 2 4 4 4 0 Domain of unknown function (DUF5082) COG5 PF10392.9 PSC71436.1 - 0.77 9.9 17.3 0.081 13.1 2.7 3.8 2 1 2 4 4 4 0 Golgi transport complex subunit 5 Laminin_II PF06009.12 PSC71436.1 - 1.3 9.1 26.6 0.21 11.6 2.6 4.2 1 1 2 4 4 4 0 Laminin Domain II DUF1664 PF07889.12 PSC71436.1 - 1.7 8.7 17.0 3.4 7.7 2.3 4.4 2 2 2 4 4 4 0 Protein of unknown function (DUF1664) MPS2 PF17060.5 PSC71436.1 - 2.6 7.2 14.6 0.26 10.5 4.2 2.5 2 1 0 2 2 2 0 Monopolar spindle protein 2 NPV_P10 PF05531.12 PSC71436.1 - 3.3 8.2 12.0 24 5.5 0.9 4.9 5 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein Spc7 PF08317.11 PSC71436.1 - 4.6 6.0 46.6 0.31 9.9 8.0 3.6 1 1 2 3 3 3 0 Spc7 kinetochore protein KASH_CCD PF14662.6 PSC71436.1 - 5.5 6.8 40.6 1.3 8.8 7.7 3.4 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 or KASH Golgin_A5 PF09787.9 PSC71436.1 - 6.4 6.2 41.3 1.3 8.4 12.2 3.2 1 1 1 3 3 3 0 Golgin subfamily A member 5 MAD PF05557.13 PSC71436.1 - 6.8 4.9 43.6 1.6 7.0 23.6 2.2 1 1 1 2 2 2 0 Mitotic checkpoint protein Surfac_D-trimer PF09006.11 PSC71436.1 - 7.7 6.5 10.5 12 5.9 1.0 4.8 4 1 1 5 5 5 0 Lung surfactant protein D coiled-coil trimerisation VWA_2 PF13519.6 PSC71437.1 - 1e-09 39.0 0.0 3.7e-09 37.2 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PSC71437.1 - 1.4e-08 34.4 0.0 3.1e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 VWA domain containing CoxE-like protein VWA PF00092.28 PSC71437.1 - 0.044 14.0 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain Thioredoxin_4 PF13462.6 PSC71437.1 - 2.3 8.3 5.2 5.2 7.2 5.2 1.5 1 0 0 1 1 1 0 Thioredoxin DUF3391 PF11871.8 PSC71437.1 - 5.1 7.6 8.0 14 6.2 8.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) SKIP_SNW PF02731.15 PSC71438.1 - 2.1e-69 232.3 0.0 2.1e-69 232.3 0.0 2.2 2 0 0 2 2 2 1 SKIP/SNW domain Cwf_Cwc_15 PF04889.12 PSC71438.1 - 0.71 9.6 18.1 1.4 8.6 18.1 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Metallophos PF00149.28 PSC71439.1 - 8.2e-35 121.2 0.0 1.6e-34 120.2 0.0 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase ABC_membrane PF00664.23 PSC71439.1 - 4.1e-31 108.6 6.7 5.5e-31 108.2 6.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PSC71439.1 - 2e-30 106.1 0.0 3.7e-30 105.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter Kelch_4 PF13418.6 PSC71439.1 - 3.6e-23 81.3 7.1 0.0016 18.4 0.1 7.2 6 1 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 PSC71439.1 - 2.7e-20 72.2 12.0 0.00035 20.8 0.0 8.0 7 1 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 PSC71439.1 - 1.9e-19 69.2 0.7 0.017 15.1 0.1 7.1 7 1 0 7 7 6 5 Kelch motif Kelch_1 PF01344.25 PSC71439.1 - 3.5e-15 55.3 0.0 0.0029 17.2 0.0 6.8 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 PSC71439.1 - 2.4e-12 46.3 0.1 0.05 13.6 0.0 6.0 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 PSC71439.1 - 6.4e-12 45.3 2.8 0.61 10.5 0.0 7.2 4 2 2 6 6 6 3 Kelch motif SMC_N PF02463.19 PSC71439.1 - 0.00036 20.1 0.0 0.0025 17.3 0.0 2.2 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain STPPase_N PF16891.5 PSC71439.1 - 0.0041 17.5 0.0 0.0089 16.5 0.0 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain AAA_25 PF13481.6 PSC71439.1 - 0.0057 16.3 0.9 0.031 13.9 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 PSC71439.1 - 0.008 15.9 0.1 0.026 14.2 0.1 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 PSC71439.1 - 0.012 16.0 0.2 0.065 13.6 0.2 2.3 1 1 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 PSC71439.1 - 0.17 11.8 0.1 0.35 10.7 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase HTH_20 PF12840.7 PSC71439.1 - 0.65 10.1 4.4 3.4 7.8 0.1 3.5 3 0 0 3 3 3 0 Helix-turn-helix domain Glyco_trans_1_4 PF13692.6 PSC71440.1 - 4e-13 49.9 0.0 9.2e-13 48.8 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 PSC71440.1 - 0.3 11.0 0.0 0.3 11.0 0.0 2.1 3 0 0 3 3 3 0 Glycosyltransferase Family 4 RCC1 PF00415.18 PSC71441.1 - 5.1e-11 43.0 21.7 5.2e-05 23.8 0.4 6.9 5 2 0 5 5 5 2 Regulator of chromosome condensation (RCC1) repeat TP6A_N PF04406.14 PSC71441.1 - 2.5e-10 40.2 0.0 4e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Type IIB DNA topoisomerase RCC1_2 PF13540.6 PSC71441.1 - 1.2e-09 37.7 26.5 0.00015 21.5 0.7 5.2 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat R3H PF01424.22 PSC71441.1 - 7e-09 35.6 0.0 1.4e-08 34.6 0.0 1.5 1 0 0 1 1 1 1 R3H domain IHABP4_N PF16174.5 PSC71441.1 - 6.3 7.4 8.3 15 6.2 8.3 1.5 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal Thioredoxin PF00085.20 PSC71442.1 - 2.6e-13 49.9 0.0 3.6e-13 49.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PSC71442.1 - 8.2e-07 29.5 0.0 1.5e-06 28.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PSC71442.1 - 3.1e-06 27.4 0.0 0.00051 20.3 0.0 2.1 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_7 PF13899.6 PSC71442.1 - 4.5e-05 23.6 0.0 8e-05 22.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 PSC71442.1 - 0.00072 19.5 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family YtxH PF12732.7 PSC71442.1 - 3.1 8.4 6.7 6.1 7.4 6.7 1.5 1 0 0 1 1 1 0 YtxH-like protein PAP_fibrillin PF04755.12 PSC71443.1 - 6.9e-52 176.3 0.0 9.4e-52 175.8 0.0 1.2 1 0 0 1 1 1 1 PAP_fibrillin TPR_2 PF07719.17 PSC71444.1 - 7.8e-08 31.9 9.1 6.9e-05 22.7 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 PSC71444.1 - 1.1e-07 31.3 2.8 1.3e-05 24.8 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 PSC71444.1 - 8e-06 25.9 0.8 8e-06 25.9 0.8 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 PSC71444.1 - 9.5e-05 22.2 2.9 0.94 9.7 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PSC71444.1 - 0.00016 21.3 0.8 0.013 15.2 0.0 2.6 2 0 0 2 2 2 1 TPR repeat DUF3150 PF11348.8 PSC71444.1 - 0.026 13.8 0.0 0.061 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3150) TPR_8 PF13181.6 PSC71444.1 - 0.027 14.7 0.4 0.11 12.7 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 PSC71444.1 - 0.06 13.4 0.1 2.4 8.3 0.0 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_12 PF13424.6 PSC71444.1 - 0.083 13.2 8.6 1.2 9.5 0.2 3.9 3 1 1 4 4 4 0 Tetratricopeptide repeat EF-hand_8 PF13833.6 PSC71444.1 - 0.2 11.5 2.1 7.2 6.5 0.0 3.0 3 0 0 3 3 3 0 EF-hand domain pair Glyco_transf_8 PF01501.20 PSC71445.1 - 2.6e-10 40.3 0.0 4.9e-10 39.4 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 PSC71445.1 - 0.013 14.9 0.0 0.022 14.1 0.0 1.5 1 1 0 1 1 1 0 Mannosyltransferase putative ADH_N PF08240.12 PSC71446.1 - 8.6e-26 90.0 0.6 8.6e-26 90.0 0.6 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Suc_Fer-like PF06999.12 PSC71446.1 - 3e-23 82.7 0.0 5.2e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like ADH_N_assoc PF13823.6 PSC71446.1 - 1.6e-05 24.7 0.1 5.5e-05 23.0 0.1 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-associated DSPc PF00782.20 PSC71447.1 - 2.5e-09 37.0 0.0 3.6e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PSC71447.1 - 0.0037 16.9 0.0 0.0046 16.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 PSC71447.1 - 0.036 14.2 0.0 0.06 13.5 0.0 1.3 1 0 0 1 1 1 0 Inositol hexakisphosphate PFK PF00365.20 PSC71449.1 - 2.3e-35 122.3 0.0 3.2e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Phosphofructokinase Cys_rich_FGFR PF00839.17 PSC71450.1 - 9.5e-97 317.1 77.1 7.4e-12 45.3 0.8 12.1 12 0 0 12 12 12 11 Cysteine rich repeat Zmiz1_N PF18028.1 PSC71450.1 - 0.008 16.5 3.8 0.57 10.5 0.3 4.4 4 0 0 4 4 4 1 Zmiz1 N-terminal tetratricopeptide repeat domain AhpC-TSA PF00578.21 PSC71451.1 - 4.6e-24 84.7 0.0 5.9e-24 84.3 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PSC71451.1 - 5.6e-19 68.3 0.0 7.3e-19 67.9 0.0 1.1 1 0 0 1 1 1 1 Redoxin NAD_binding_1 PF00175.21 PSC71452.1 - 2.9e-10 40.8 0.0 5.3e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 PSC71452.1 - 0.039 14.3 0.0 0.059 13.7 0.0 1.3 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain DM13 PF10517.9 PSC71453.1 - 5.7e-18 65.4 0.0 1.2e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 Electron transfer DM13 DOMON PF03351.17 PSC71453.1 - 5.8e-15 55.6 0.0 9.1e-15 55.0 0.0 1.3 1 0 0 1 1 1 1 DOMON domain zf-CHY PF05495.12 PSC71454.1 - 6.9e-14 52.1 8.0 6.9e-14 52.1 8.0 3.1 2 1 1 3 3 3 1 CHY zinc finger PSCyt3 PF07627.11 PSC71454.1 - 0.36 11.1 2.2 8.3 6.8 0.1 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) Cytochrome_C7 PF14522.6 PSC71454.1 - 0.49 10.4 15.8 0.16 12.0 3.4 3.2 2 1 1 3 3 3 0 Cytochrome c7 and related cytochrome c Paired_CXXCH_1 PF09699.10 PSC71454.1 - 1.1 9.0 9.5 2.4 8.0 0.0 4.0 4 0 0 4 4 4 0 Doubled CXXCH motif (Paired_CXXCH_1) Stc1 PF12898.7 PSC71454.1 - 6.1 7.5 11.8 1.3 9.6 2.2 3.2 2 1 0 2 2 2 0 Stc1 domain AAA PF00004.29 PSC71455.1 - 8e-97 320.8 0.0 6.8e-47 159.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PSC71455.1 - 6.4e-27 93.1 4.0 1.7e-13 50.2 1.2 2.8 2 0 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 PSC71455.1 - 7.4e-23 80.5 1.9 2.7e-22 78.7 1.5 2.2 2 0 0 2 2 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 PSC71455.1 - 1.5e-14 54.0 0.0 8.5e-06 25.6 0.0 3.0 3 1 0 3 3 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PSC71455.1 - 6.5e-13 49.4 0.2 0.00023 21.6 0.0 4.1 2 2 0 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 PSC71455.1 - 8.5e-13 48.8 0.0 3.1e-06 27.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) CDC48_2 PF02933.17 PSC71455.1 - 2.2e-12 46.6 0.0 4.9e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_33 PF13671.6 PSC71455.1 - 9.1e-11 42.1 0.0 4.6e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 PSC71455.1 - 3.3e-10 40.1 0.1 8.8e-05 22.5 0.0 3.2 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PSC71455.1 - 3.6e-10 40.2 0.3 0.014 15.6 0.1 4.7 3 2 1 4 4 3 2 AAA domain TIP49 PF06068.13 PSC71455.1 - 1.8e-08 34.0 0.0 0.0013 18.0 0.0 2.6 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 PSC71455.1 - 1.8e-08 34.5 0.0 0.0034 17.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 PSC71455.1 - 6.6e-08 33.2 0.0 0.014 15.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 PSC71455.1 - 3.7e-07 29.8 0.2 0.023 14.1 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 PSC71455.1 - 5e-07 30.1 0.0 0.0071 16.7 0.0 2.7 2 0 0 2 2 2 2 RNA helicase IstB_IS21 PF01695.17 PSC71455.1 - 1.5e-06 28.0 0.0 0.049 13.4 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Vps4_C PF09336.10 PSC71455.1 - 4.1e-06 26.7 0.3 0.00024 21.0 0.1 2.8 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain ATPase_2 PF01637.18 PSC71455.1 - 1.1e-05 25.5 1.8 0.25 11.2 0.0 3.7 4 1 0 4 4 2 2 ATPase domain predominantly from Archaea Viral_helicase1 PF01443.18 PSC71455.1 - 1.2e-05 25.2 0.0 0.0019 18.0 0.0 2.8 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase AAA_28 PF13521.6 PSC71455.1 - 1.7e-05 25.1 0.0 0.11 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.6 PSC71455.1 - 2.2e-05 24.9 0.0 0.23 11.9 0.0 2.9 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.17 PSC71455.1 - 2.8e-05 23.3 0.1 0.038 13.1 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 TsaE PF02367.17 PSC71455.1 - 2.9e-05 24.1 0.0 0.18 11.8 0.0 2.5 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 PSC71455.1 - 2.9e-05 23.5 0.3 2.8 7.2 0.0 3.4 3 0 0 3 3 3 1 KaiC ABC_tran PF00005.27 PSC71455.1 - 3.3e-05 24.4 0.1 0.077 13.5 0.0 3.0 2 1 0 2 2 2 1 ABC transporter Zeta_toxin PF06414.12 PSC71455.1 - 3.9e-05 23.0 0.0 0.14 11.4 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin AAA_7 PF12775.7 PSC71455.1 - 4.2e-05 23.1 0.0 0.18 11.3 0.0 2.8 2 1 0 2 2 2 2 P-loop containing dynein motor region NACHT PF05729.12 PSC71455.1 - 4.3e-05 23.5 0.2 0.34 10.8 0.0 3.6 3 1 1 4 4 4 1 NACHT domain Bac_DnaA PF00308.18 PSC71455.1 - 5.6e-05 23.1 0.0 0.3 10.9 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_24 PF13479.6 PSC71455.1 - 6e-05 22.8 0.0 0.11 12.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 PSC71455.1 - 7.5e-05 22.4 2.8 2.3 7.7 0.1 4.3 3 2 0 4 4 4 1 AAA domain Sigma54_activat PF00158.26 PSC71455.1 - 8.1e-05 22.4 0.0 0.63 9.7 0.0 3.0 2 1 0 2 2 2 2 Sigma-54 interaction domain UFD1 PF03152.14 PSC71455.1 - 0.00011 21.8 0.0 0.00018 21.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 NB-ARC PF00931.22 PSC71455.1 - 0.00019 20.7 0.0 0.28 10.4 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain DUF815 PF05673.13 PSC71455.1 - 0.00026 20.2 0.0 0.058 12.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NTPase_1 PF03266.15 PSC71455.1 - 0.00043 20.2 1.6 3.2 7.6 0.0 4.5 3 1 0 4 4 4 0 NTPase ResIII PF04851.15 PSC71455.1 - 0.0005 20.1 0.0 0.095 12.7 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Sigma54_activ_2 PF14532.6 PSC71455.1 - 0.00057 20.0 0.0 0.4 10.8 0.0 2.6 2 0 0 2 2 2 1 Sigma-54 interaction domain DUF2075 PF09848.9 PSC71455.1 - 0.0012 18.1 0.0 0.84 8.8 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_3 PF07726.11 PSC71455.1 - 0.0015 18.4 0.0 2 8.2 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.6 PSC71455.1 - 0.0021 18.2 0.0 0.97 9.5 0.0 2.4 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_19 PF13245.6 PSC71455.1 - 0.0056 17.0 0.6 7.7 6.8 0.1 3.2 3 1 1 4 4 2 0 AAA domain Rad17 PF03215.15 PSC71455.1 - 0.0068 16.4 0.0 1 9.2 0.0 2.6 2 1 0 2 2 2 1 Rad17 P-loop domain PhoH PF02562.16 PSC71455.1 - 0.011 15.3 2.3 2.1 7.7 0.0 2.8 3 0 0 3 3 2 0 PhoH-like protein SRPRB PF09439.10 PSC71455.1 - 0.022 14.2 1.8 27 4.1 0.1 4.2 4 1 0 4 4 4 0 Signal recognition particle receptor beta subunit AAA_11 PF13086.6 PSC71455.1 - 0.022 14.6 0.0 6.5 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 PSC71455.1 - 0.022 14.9 0.3 6.7 6.8 0.0 2.8 3 0 0 3 3 2 0 Shikimate kinase Cytidylate_kin PF02224.18 PSC71455.1 - 0.028 14.2 0.0 5.8 6.6 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase Zot PF05707.12 PSC71455.1 - 0.038 13.6 0.0 0.56 9.8 0.0 2.6 2 0 0 2 2 2 0 Zonular occludens toxin (Zot) KAP_NTPase PF07693.14 PSC71455.1 - 0.042 13.1 0.2 2 7.6 0.0 3.0 2 2 2 4 4 4 0 KAP family P-loop domain AAA_29 PF13555.6 PSC71455.1 - 0.071 12.9 0.0 6.4 6.6 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain PduV-EutP PF10662.9 PSC71455.1 - 0.073 12.8 0.0 3.3 7.4 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.6 PSC71455.1 - 0.079 12.7 0.4 13 5.5 0.1 2.6 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 PSC71455.1 - 0.1 11.6 0.0 15 4.5 0.0 2.8 3 0 0 3 3 3 0 Type II/IV secretion system protein TniB PF05621.11 PSC71455.1 - 0.16 11.4 0.0 21 4.4 0.0 3.3 3 0 0 3 3 3 0 Bacterial TniB protein DNTTIP1_dimer PF18192.1 PSC71455.1 - 0.16 12.3 0.1 2.6 8.4 0.0 3.0 3 0 0 3 3 2 0 DNTTIP1 dimerisation domain AAA_23 PF13476.6 PSC71455.1 - 0.17 12.4 1.6 25 5.3 0.0 2.9 3 0 0 3 3 2 0 AAA domain Raffinose_syn PF05691.12 PSC71456.1 - 1.3e-93 314.3 0.0 7.7e-52 176.1 0.1 5.8 3 1 3 6 6 6 6 Raffinose synthase or seed imbibition protein Sip1 BAR PF03114.18 PSC71457.1 - 9.2e-09 35.3 2.1 0.00021 21.0 0.4 3.2 3 0 0 3 3 3 2 BAR domain Ala_racemase_N PF01168.20 PSC71457.1 - 7.5e-05 22.5 5.9 0.033 13.8 0.3 3.6 3 1 1 4 4 4 2 Alanine racemase, N-terminal domain TMEM65 PF10507.9 PSC71457.1 - 0.0081 16.1 0.1 0.028 14.3 0.1 1.9 1 0 0 1 1 1 1 Transmembrane protein 65 APG6_N PF17675.1 PSC71457.1 - 3.6 8.1 17.8 18 5.9 0.1 4.0 4 0 0 4 4 4 0 Apg6 coiled-coil region Mac PF12464.8 PSC71458.1 - 7.6e-14 51.7 0.1 1.1e-13 51.2 0.1 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.24 PSC71458.1 - 4e-11 42.2 8.9 1.7e-08 33.9 2.5 2.7 3 0 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 PSC71458.1 - 9.1e-10 38.1 7.7 4.2e-08 32.8 2.9 2.8 3 0 0 3 3 3 2 Hexapeptide repeat of succinyl-transferase Sfi1 PF08457.10 PSC71459.1 - 0.0016 17.1 7.4 0.0016 17.1 7.4 15.1 2 2 13 15 15 15 11 Sfi1 spindle body protein TGT PF01702.18 PSC71460.1 - 1.2e-114 383.1 0.0 1.4e-114 382.9 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Pestivirus_E2 PF16329.5 PSC71460.1 - 0.029 13.2 0.0 0.043 12.7 0.0 1.1 1 0 0 1 1 1 0 Pestivirus envelope glycoprotein E2 zf-C2H2_12 PF18658.1 PSC71460.1 - 0.17 11.5 1.2 0.41 10.2 1.2 1.6 1 0 0 1 1 1 0 Zinc-finger C2H2-type IMS PF00817.20 PSC71461.1 - 5.7e-43 146.5 0.8 1.1e-42 145.6 0.0 2.0 2 0 0 2 2 2 1 impB/mucB/samB family IMS_C PF11799.8 PSC71461.1 - 5.5e-19 69.0 0.0 1.4e-18 67.7 0.0 1.7 1 0 0 1 1 1 1 impB/mucB/samB family C-terminal domain BRCT_2 PF16589.5 PSC71461.1 - 1.2e-07 32.0 0.0 2.5e-07 31.0 0.0 1.6 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 PSC71461.1 - 1.4e-06 28.2 0.0 3.6e-06 26.8 0.0 1.8 2 0 0 2 2 2 1 twin BRCT domain BRCT PF00533.26 PSC71461.1 - 1.2e-05 25.6 0.0 2.7e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain IMS_HHH PF11798.8 PSC71461.1 - 7.1e-05 22.9 0.0 0.00017 21.7 0.0 1.7 1 0 0 1 1 1 1 IMS family HHH motif LIG3_BRCT PF16759.5 PSC71461.1 - 0.00019 21.6 0.0 0.00043 20.5 0.0 1.6 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain UBM PF14377.6 PSC71461.1 - 0.0019 17.6 1.9 0.0019 17.6 1.9 5.7 5 0 0 5 5 5 2 Ubiquitin binding region ALIX_LYPXL_bnd PF13949.6 PSC71461.1 - 0.0031 16.8 2.4 0.0031 16.8 2.4 2.5 2 0 0 2 2 2 1 ALIX V-shaped domain binding to HIV HTH_15 PF12324.8 PSC71461.1 - 0.29 11.1 2.6 1.8 8.6 1.4 2.9 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase Aldedh PF00171.22 PSC71464.1 - 3.3e-05 22.6 7.2 5e-05 22.0 0.0 3.1 3 1 0 3 3 3 2 Aldehyde dehydrogenase family ubiquitin PF00240.23 PSC71466.1 - 3.3e-05 23.5 0.0 7.2e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family APG17 PF04108.12 PSC71466.1 - 0.00013 21.3 8.0 0.00045 19.4 0.3 2.8 2 1 1 3 3 3 2 Autophagy protein Apg17 DUF812 PF05667.11 PSC71466.1 - 0.0024 16.8 0.4 0.26 10.1 0.1 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF812) AAA_13 PF13166.6 PSC71466.1 - 0.039 12.6 3.4 1.2 7.7 0.3 2.1 2 0 0 2 2 2 0 AAA domain Fer4_20 PF14691.6 PSC71466.1 - 0.092 12.5 0.6 0.34 10.7 0.9 1.7 2 0 0 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster DUF1664 PF07889.12 PSC71466.1 - 0.38 10.8 2.7 2.9 8.0 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) CENP-K PF11802.8 PSC71466.1 - 0.43 10.1 3.9 0.77 9.3 0.4 2.3 1 1 1 2 2 2 0 Centromere-associated protein K TMF_TATA_bd PF12325.8 PSC71466.1 - 0.63 10.3 8.4 11 6.3 0.1 4.4 4 0 0 4 4 4 0 TATA element modulatory factor 1 TATA binding DHR10 PF18595.1 PSC71466.1 - 1.3 9.1 18.6 0.6 10.2 0.3 4.3 4 0 0 4 4 4 0 Designed helical repeat protein 10 domain Spc7 PF08317.11 PSC71466.1 - 1.3 7.9 9.9 1.1 8.1 0.6 3.2 2 1 1 3 3 3 0 Spc7 kinetochore protein Laminin_II PF06009.12 PSC71466.1 - 2.5 8.1 7.2 1.7 8.6 0.5 2.8 3 0 0 3 3 3 0 Laminin Domain II DUF4404 PF14357.6 PSC71466.1 - 3.8 8.2 7.1 16 6.2 2.3 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) F-box PF00646.33 PSC71467.1 - 0.097 12.6 0.7 4.3 7.3 0.0 2.6 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.7 PSC71467.1 - 0.66 10.5 4.4 1e+02 3.5 0.1 4.8 4 3 0 4 4 4 0 Leucine Rich repeats (2 copies) DnaJ PF00226.31 PSC71468.1 - 8e-19 67.5 0.1 2e-18 66.2 0.1 1.7 1 0 0 1 1 1 1 DnaJ domain CS PF04969.16 PSC71468.1 - 2.6e-05 25.1 0.0 0.5 11.4 0.0 2.6 2 1 0 2 2 2 2 CS domain zf-B_box PF00643.24 PSC71468.1 - 0.00037 20.6 2.9 0.00075 19.6 2.9 1.4 1 0 0 1 1 1 1 B-box zinc finger Glyco_transf_43 PF03360.16 PSC71468.1 - 0.13 12.0 0.0 5.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Glycosyltransferase family 43 BING4CT PF08149.11 PSC71469.1 - 1.3e-36 124.3 0.0 2.4e-34 117.0 0.0 3.0 3 0 0 3 3 3 1 BING4CT (NUC141) domain ANAPC4_WD40 PF12894.7 PSC71469.1 - 1.3e-07 31.8 0.0 0.18 12.1 0.0 4.4 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PSC71469.1 - 2.9e-07 31.1 3.5 7.1e-06 26.7 0.0 4.4 7 0 0 7 7 7 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 PSC71469.1 - 0.018 14.1 0.0 0.026 13.6 0.0 1.2 1 0 0 1 1 1 0 Coatomer WD associated region Cytochrom_D1 PF02239.16 PSC71469.1 - 0.018 13.6 0.0 0.96 7.9 0.0 2.4 1 1 0 2 2 2 0 Cytochrome D1 heme domain PQQ_2 PF13360.6 PSC71469.1 - 0.072 12.7 0.0 11 5.5 0.1 2.9 1 1 1 2 2 2 0 PQQ-like domain Cpn60_TCP1 PF00118.24 PSC71471.1 - 1.1e-150 502.6 4.2 1.2e-150 502.4 4.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family NdhS PF11623.8 PSC71471.1 - 0.015 15.0 0.2 0.037 13.7 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H dehydrogenase subunit S Phage_Mu_Gp45 PF06890.12 PSC71471.1 - 0.079 12.7 0.2 0.31 10.8 0.1 2.1 2 0 0 2 2 2 0 Bacteriophage Mu Gp45 protein Sulfotransfer_2 PF03567.14 PSC71472.1 - 0.00027 20.9 0.0 0.012 15.6 0.0 2.8 3 0 0 3 3 3 1 Sulfotransferase family WW PF00397.26 PSC71472.1 - 0.032 14.3 6.0 0.079 13.1 6.0 1.7 1 0 0 1 1 1 0 WW domain betaPIX_CC PF16523.5 PSC71472.1 - 0.15 11.9 1.8 0.32 10.9 1.8 1.5 1 0 0 1 1 1 0 betaPIX coiled coil CDC45 PF02724.14 PSC71473.1 - 1.4e-121 406.9 0.1 4.4e-92 309.4 0.0 2.9 1 1 1 2 2 2 2 CDC45-like protein FtsJ PF01728.19 PSC71474.1 - 8.3e-55 185.6 0.0 1.5e-54 184.8 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.12 PSC71474.1 - 5.7e-45 153.6 19.7 5.7e-45 153.6 19.7 3.3 3 0 0 3 3 3 1 Spb1 C-terminal domain DUF3381 PF11861.8 PSC71474.1 - 1.7e-38 132.1 4.8 1.7e-38 132.1 4.8 4.7 3 2 3 6 6 6 1 Domain of unknown function (DUF3381) KH_1 PF00013.29 PSC71475.1 - 0.00024 20.9 0.1 0.0019 18.0 0.1 2.0 2 0 0 2 2 2 1 KH domain KH_2 PF07650.17 PSC71475.1 - 0.095 12.5 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 KH domain DUF4345 PF14248.6 PSC71476.1 - 0.012 15.5 2.6 0.046 13.6 2.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4345) DUF4225 PF13988.6 PSC71476.1 - 0.024 14.2 0.0 0.037 13.6 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4225) Raffinose_syn PF05691.12 PSC71477.1 - 4.3e-169 563.8 0.0 8.3e-119 397.5 0.0 2.0 2 0 0 2 2 2 2 Raffinose synthase or seed imbibition protein Sip1 GTP1_OBG PF01018.22 PSC71478.1 - 1.3e-54 184.0 0.4 2.2e-54 183.3 0.4 1.4 1 0 0 1 1 1 1 GTP1/OBG DUF1967 PF09269.11 PSC71478.1 - 2.9e-21 75.2 0.2 1.1e-20 73.3 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1967) MMR_HSR1 PF01926.23 PSC71478.1 - 9.4e-21 74.0 0.0 1.5e-20 73.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PSC71478.1 - 4.3e-09 36.1 0.0 6.9e-09 35.4 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 PSC71478.1 - 0.0067 15.4 0.1 2.6 7.0 0.0 2.2 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB Arf PF00025.21 PSC71478.1 - 0.009 15.5 0.0 0.07 12.6 0.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 PSC71478.1 - 0.027 14.0 0.0 8.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 PSC71478.1 - 0.21 12.1 0.0 0.72 10.4 0.0 1.8 2 0 0 2 2 2 0 ABC transporter Polysacc_deac_1 PF01522.21 PSC71479.1 - 2.7e-09 37.0 0.0 5.3e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide deacetylase Peptidase_S8 PF00082.22 PSC71480.1 - 2.1e-29 102.7 16.4 2.1e-29 102.7 16.4 3.3 1 1 2 3 3 3 2 Subtilase family ETRAMP PF09716.10 PSC71480.1 - 0.69 10.0 7.1 5.2 7.2 1.1 2.7 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Utp14 PF04615.13 PSC71480.1 - 2.1 6.8 50.1 2.9 6.4 50.1 1.1 1 0 0 1 1 1 0 Utp14 protein SARAF PF06682.12 PSC71480.1 - 2.3 7.8 44.5 4.2 6.9 44.5 1.5 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SR-25 PF10500.9 PSC71480.1 - 7.3 6.1 58.6 1.1 8.8 34.0 2.3 1 1 1 2 2 2 0 Nuclear RNA-splicing-associated protein PRP1_N PF06424.12 PSC71481.1 - 8.7e-47 159.2 1.6 1.8e-46 158.2 1.6 1.5 1 0 0 1 1 1 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 PSC71481.1 - 8.2e-34 113.4 55.8 0.00025 21.6 2.2 15.1 4 3 11 15 15 15 13 Tetratricopeptide repeat TPR_19 PF14559.6 PSC71481.1 - 1.9e-26 92.4 15.8 1.1e-06 29.1 0.0 9.7 8 2 1 9 9 9 5 Tetratricopeptide repeat TPR_17 PF13431.6 PSC71481.1 - 1e-12 47.4 1.0 0.27 11.7 0.0 8.6 7 2 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 PSC71481.1 - 2.9e-07 31.0 41.8 0.0019 18.8 5.1 8.4 7 2 0 8 8 8 3 Tetratricopeptide repeat TPR_2 PF07719.17 PSC71481.1 - 1.2e-05 25.0 23.7 1.5 9.1 0.0 9.6 11 0 0 11 11 10 3 Tetratricopeptide repeat Suf PF05843.14 PSC71481.1 - 1.6e-05 25.1 0.0 0.095 12.7 0.0 4.6 5 0 0 5 5 5 1 Suppressor of forked protein (Suf) TPR_8 PF13181.6 PSC71481.1 - 5.6e-05 23.0 2.9 17 5.9 0.0 7.7 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 PSC71481.1 - 0.011 15.4 0.1 95 2.8 0.1 5.6 5 2 3 8 8 8 0 TPR repeat Retrotrans_gag PF03732.17 PSC71481.1 - 0.017 15.3 1.5 0.69 10.2 0.3 2.8 2 0 0 2 2 2 0 Retrotransposon gag protein SNAP PF14938.6 PSC71481.1 - 0.022 14.2 0.4 0.086 12.2 0.4 2.0 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_6 PF13174.6 PSC71481.1 - 0.025 15.2 20.7 7.7 7.4 0.1 9.8 11 1 0 11 11 11 0 Tetratricopeptide repeat NRDE-2 PF08424.10 PSC71481.1 - 0.068 12.3 17.0 0.088 11.9 0.0 5.1 6 1 1 7 7 7 0 NRDE-2, necessary for RNA interference CP12 PF02672.15 PSC71481.1 - 0.12 13.1 4.9 0.088 13.6 1.0 2.9 2 0 0 2 2 1 0 CP12 domain NARP1 PF12569.8 PSC71481.1 - 1.2 8.0 11.9 0.083 11.8 0.3 3.9 4 1 0 5 5 5 0 NMDA receptor-regulated protein 1 HAT PF02184.16 PSC71481.1 - 9.3 6.3 7.3 6.8 6.8 0.1 4.5 7 0 0 7 7 7 0 HAT (Half-A-TPR) repeat Peptidase_S8 PF00082.22 PSC71482.1 - 1.7e-39 135.8 0.2 2.8e-39 135.2 0.2 1.2 1 0 0 1 1 1 1 Subtilase family Patatin PF01734.22 PSC71483.1 - 8.1e-09 35.9 2.7 1.8e-07 31.6 2.7 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase cobW PF02492.19 PSC71484.1 - 7.2e-52 175.5 0.1 1.1e-51 174.9 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 PSC71484.1 - 7.8e-19 67.4 0.1 1.7e-18 66.3 0.1 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain SHOCT PF09851.9 PSC71484.1 - 6.2e-05 22.6 1.0 0.00041 20.0 0.0 2.4 2 0 0 2 2 2 1 Short C-terminal domain RsgA_GTPase PF03193.16 PSC71484.1 - 0.00035 20.5 0.0 0.34 10.8 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 PSC71484.1 - 0.0023 18.3 1.3 0.0053 17.2 0.1 2.4 2 1 0 2 2 2 1 AAA ATPase domain bPH_2 PF03703.14 PSC71484.1 - 0.0043 17.2 0.0 0.015 15.4 0.0 1.9 2 0 0 2 2 1 1 Bacterial PH domain AAA_29 PF13555.6 PSC71484.1 - 0.017 14.9 0.0 0.045 13.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 PSC71484.1 - 0.017 15.7 0.9 0.05 14.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain GTP_EFTU PF00009.27 PSC71484.1 - 0.029 13.9 0.4 0.28 10.7 0.4 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain TsaE PF02367.17 PSC71484.1 - 0.051 13.6 0.0 0.13 12.2 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE MMR_HSR1 PF01926.23 PSC71484.1 - 0.059 13.5 0.0 0.27 11.3 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.6 PSC71484.1 - 0.065 13.5 0.0 0.5 10.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 PSC71484.1 - 0.073 13.6 0.0 0.15 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.17 PSC71484.1 - 0.3 10.8 0.6 3.4 7.4 0.6 2.1 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein Ufd2P_core PF10408.9 PSC71485.1 - 6e-93 312.6 0.0 7.4e-93 312.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin elongating factor core RabGAP-TBC PF00566.18 PSC71485.1 - 3.3e-51 174.0 0.0 4.9e-51 173.4 0.0 1.3 1 0 0 1 1 1 1 Rab-GTPase-TBC domain UQ_con PF00179.26 PSC71485.1 - 6.6e-23 80.9 0.0 1.4e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 PSC71485.1 - 0.12 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 UEV domain Spt20 PF12090.8 PSC71486.1 - 1.8 8.1 8.1 2.4 7.7 8.1 1.3 1 0 0 1 1 1 0 Spt20 family DUF89 PF01937.19 PSC71487.1 - 6.9e-40 137.1 0.0 8.3e-40 136.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF89 MLTR_LBD PF17765.1 PSC71487.1 - 0.042 14.0 0.3 0.12 12.4 0.3 1.8 1 0 0 1 1 1 0 MmyB-like transcription regulator ligand binding domain Hemerythrin PF01814.23 PSC71488.1 - 1.8e-14 54.5 11.0 2.5e-11 44.3 6.0 2.0 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain Phg_2220_C PF09524.10 PSC71488.1 - 0.15 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Conserved phage C-terminus (Phg_2220_C) WD40 PF00400.32 PSC71489.1 - 9.8e-46 152.8 19.9 2.1e-11 44.2 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC71489.1 - 5.7e-17 61.8 0.0 7.2e-05 23.0 0.0 5.1 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PSC71489.1 - 1.6e-05 24.9 0.0 0.064 13.1 0.0 3.4 2 2 2 5 5 5 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 PSC71489.1 - 0.00061 18.6 1.5 0.3 9.7 0.1 3.5 2 2 1 3 3 3 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 PSC71489.1 - 0.0027 16.7 0.1 0.04 12.9 0.0 2.5 2 1 1 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 PSC71489.1 - 0.0098 15.3 0.0 3.6 6.8 0.0 2.7 2 1 1 3 3 3 2 WD40-like domain Frtz PF11768.8 PSC71489.1 - 0.031 12.6 0.0 2.5 6.3 0.0 2.7 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Coatomer_WDAD PF04053.14 PSC71489.1 - 0.053 12.6 0.0 0.24 10.4 0.0 1.9 2 1 0 2 2 2 0 Coatomer WD associated region Nbas_N PF15492.6 PSC71489.1 - 0.053 12.8 0.2 1.5 8.1 0.1 2.8 1 1 2 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Cytochrom_D1 PF02239.16 PSC71489.1 - 0.2 10.2 0.1 1.9 6.9 0.0 2.1 2 0 0 2 2 2 0 Cytochrome D1 heme domain PQQ_3 PF13570.6 PSC71489.1 - 5.7 7.6 0.0 5.7 7.6 0.0 5.4 7 0 0 7 7 6 0 PQQ-like domain Na_H_Exchanger PF00999.21 PSC71490.1 - 2.9e-66 223.8 35.1 4.7e-66 223.1 35.1 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 PSC71490.1 - 3.2e-21 75.8 0.1 7.3e-21 74.6 0.1 1.7 1 0 0 1 1 1 1 TrkA-N domain RTC_insert PF05189.13 PSC71490.1 - 0.0037 17.8 0.5 0.0037 17.8 0.5 2.1 2 0 0 2 2 2 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain YqfQ PF14181.6 PSC71490.1 - 2.3 8.4 6.6 6.9 6.8 6.6 1.8 1 0 0 1 1 1 0 YqfQ-like protein Cytochrom_B561 PF03188.16 PSC71491.1 - 3e-23 82.5 2.3 3e-23 82.5 2.3 1.9 2 1 1 3 3 3 1 Eukaryotic cytochrome b561 PhyH PF05721.13 PSC71492.1 - 1.5e-53 182.2 0.0 1.9e-53 181.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Cellulase PF00150.18 PSC71493.1 - 2e-12 47.2 0.0 5e-12 45.8 0.0 1.5 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 PSC71493.1 - 7e-05 22.3 0.1 0.00023 20.6 0.0 1.7 2 0 0 2 2 2 1 Beta-galactosidase Complex1_51K PF01512.17 PSC71494.1 - 1.6e-46 157.9 0.0 5e-46 156.3 0.0 1.9 2 0 0 2 2 2 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 PSC71494.1 - 3.8e-26 91.0 0.1 1.4e-25 89.2 0.0 2.1 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region Amino_oxidase PF01593.24 PSC71494.1 - 2.4e-08 33.7 0.0 6.4e-06 25.7 0.0 2.4 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase SLBB PF10531.9 PSC71494.1 - 1.5e-07 31.2 0.0 5.4e-07 29.4 0.0 2.1 1 0 0 1 1 1 1 SLBB domain TPR_2 PF07719.17 PSC71494.1 - 1.9e-07 30.6 10.1 0.0055 16.7 0.2 5.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 PSC71494.1 - 2.1e-05 24.3 9.5 0.11 12.8 0.1 5.0 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 PSC71494.1 - 2.7e-05 23.8 7.8 0.0044 16.8 0.2 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 PSC71494.1 - 5.3e-05 22.8 0.0 1 9.1 0.0 3.8 4 0 0 4 4 4 2 TPR repeat TPR_14 PF13428.6 PSC71494.1 - 0.0026 18.4 1.6 0.066 14.1 0.4 8.3 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_9 PF13371.6 PSC71494.1 - 0.23 11.6 12.6 0.035 14.3 2.5 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 PSC71494.1 - 0.99 10.2 7.7 1.6e+02 3.2 1.4 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat ELFV_dehydrog PF00208.21 PSC71495.1 - 9.2e-82 274.4 1.0 1.3e-81 273.9 1.0 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 PSC71495.1 - 2.3e-45 153.6 0.0 6.4e-45 152.2 0.0 1.8 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 PSC71495.1 - 0.014 15.8 0.0 0.052 14.0 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 PSC71495.1 - 0.044 13.9 0.1 0.11 12.6 0.1 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF1241 PF06840.11 PSC71495.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Ubiquitin_2 PF14560.6 PSC71495.1 - 0.17 12.3 0.0 0.43 11.1 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain ELFV_dehydrog PF00208.21 PSC71496.1 - 5.2e-79 265.4 1.1 7.3e-79 264.9 1.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 PSC71496.1 - 2.4e-45 153.6 0.0 6.5e-45 152.2 0.0 1.8 2 0 0 2 2 2 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain NAD_binding_7 PF13241.6 PSC71496.1 - 0.012 16.0 0.1 0.044 14.2 0.0 2.0 2 0 0 2 2 2 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.21 PSC71496.1 - 0.031 14.3 0.1 0.071 13.2 0.1 1.6 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DUF1241 PF06840.11 PSC71496.1 - 0.14 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1241) Ubiquitin_2 PF14560.6 PSC71496.1 - 0.16 12.4 0.0 0.44 11.0 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain WD40 PF00400.32 PSC71497.1 - 1.4e-20 73.3 18.3 1.6e-05 25.5 0.0 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC71497.1 - 6.9e-07 29.5 0.6 3.1 8.2 0.0 4.5 4 1 1 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain RPA_C PF08784.11 PSC71498.1 - 3.5e-16 59.8 1.1 7.9e-16 58.6 0.2 1.9 2 0 0 2 2 2 1 Replication protein A C terminal tRNA_anti-codon PF01336.25 PSC71498.1 - 5.2e-06 26.4 0.1 1e-05 25.4 0.1 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain RMI2 PF16100.5 PSC71498.1 - 0.00012 21.9 0.0 0.00018 21.3 0.0 1.3 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 CDC24_OB3 PF17244.2 PSC71498.1 - 0.042 13.6 0.0 0.063 13.0 0.0 1.2 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 TFA2_Winged_2 PF18121.1 PSC71498.1 - 0.17 11.6 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 Biopterin_H PF00351.21 PSC71499.1 - 4.3e-99 331.7 0.0 5.5e-99 331.3 0.0 1.0 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase HPP PF04982.13 PSC71500.1 - 5.9e-37 126.6 6.8 9.6e-37 125.9 6.8 1.3 1 0 0 1 1 1 1 HPP family UbiA PF01040.18 PSC71500.1 - 0.00045 19.6 0.0 0.00045 19.6 0.0 2.4 2 1 0 2 2 2 1 UbiA prenyltransferase family ArgJ PF01960.18 PSC71501.1 - 5.5e-130 433.5 8.6 4.3e-129 430.5 8.6 1.9 1 1 0 1 1 1 1 ArgJ family FTCD_N PF07837.12 PSC71502.1 - 7.6e-46 156.1 0.5 1.9e-45 154.8 0.5 1.7 1 1 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain B12D PF06522.11 PSC71502.1 - 0.01 15.6 0.0 0.03 14.1 0.0 1.8 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit FTCD PF02971.14 PSC71502.1 - 0.084 12.9 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Formiminotransferase domain OHCU_decarbox PF09349.10 PSC71502.1 - 0.17 12.4 1.5 0.31 11.5 1.5 1.4 1 0 0 1 1 1 0 OHCU decarboxylase CAP PF00188.26 PSC71503.1 - 3.9e-21 76.2 2.3 6.3e-21 75.5 2.3 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family SepSecS PF05889.13 PSC71504.1 - 2.1e-121 405.3 0.0 2.1e-109 365.8 0.0 2.0 2 0 0 2 2 2 2 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 PSC71504.1 - 0.00042 19.7 0.1 0.00056 19.3 0.1 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DUF4054 PF13262.6 PSC71504.1 - 8.9 6.4 9.7 13 5.8 1.9 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4054) RINT1_TIP1 PF04437.13 PSC71505.1 - 2.3e-28 99.4 0.0 5.9e-28 98.0 0.0 1.7 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Fez1 PF06818.15 PSC71505.1 - 0.0008 19.9 21.4 0.0008 19.9 21.4 8.6 2 1 4 7 7 7 1 Fez1 Spc29 PF17082.5 PSC71505.1 - 0.042 13.7 6.4 0.1 12.4 0.0 3.6 3 0 0 3 3 3 0 Spindle Pole Component 29 Metallophos PF00149.28 PSC71506.1 - 1.5e-08 35.4 0.0 3.2e-08 34.3 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Dus PF01207.17 PSC71507.1 - 1.5e-65 221.4 0.0 2e-65 220.9 0.0 1.1 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) PEP_mutase PF13714.6 PSC71507.1 - 0.067 12.6 1.3 0.74 9.2 1.3 2.2 1 1 1 2 2 2 0 Phosphoenolpyruvate phosphomutase DUF846 PF05832.12 PSC71508.1 - 1e-51 174.6 9.8 1.2e-51 174.4 9.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Sulfotransfer_3 PF13469.6 PSC71510.1 - 7.1e-15 56.0 0.2 5.6e-11 43.2 0.1 2.9 1 1 1 2 2 2 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 PSC71510.1 - 2e-10 40.6 0.0 2.2e-09 37.2 0.0 2.1 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 PSC71510.1 - 0.0035 17.2 0.0 0.0059 16.5 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain ABC2_membrane PF01061.24 PSC71511.1 - 2.6e-35 121.8 15.1 3.7e-35 121.3 15.1 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PSC71511.1 - 4.4e-13 49.9 0.1 2.1e-12 47.7 0.0 1.9 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 PSC71511.1 - 7.7e-07 28.5 15.0 1.2e-06 27.9 15.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_16 PF13191.6 PSC71511.1 - 0.01 16.3 0.6 0.01 16.3 0.6 2.7 2 1 0 2 2 2 0 AAA ATPase domain DUF572 PF04502.13 PSC71511.1 - 0.038 13.6 3.0 0.056 13.1 3.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) TAF4 PF05236.14 PSC71511.1 - 0.057 13.2 12.4 0.1 12.3 12.4 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family AAA_25 PF13481.6 PSC71511.1 - 4.8 6.7 15.5 0.2 11.2 1.2 3.4 3 0 0 3 3 3 0 AAA domain mTERF PF02536.14 PSC71512.1 - 2.8e-28 98.7 0.0 4.8e-20 71.7 0.0 2.8 1 1 1 2 2 2 2 mTERF DUF4287 PF14117.6 PSC71512.1 - 0.044 13.9 0.0 1.6 8.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4287) Pkinase PF00069.25 PSC71514.1 - 1.2e-17 64.2 0.0 2e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC71514.1 - 4.6e-10 39.2 0.0 7.2e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Thioredoxin PF00085.20 PSC71514.1 - 3.8e-09 36.5 0.0 7.1e-09 35.6 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Pkinase_fungal PF17667.1 PSC71514.1 - 3.9e-08 32.5 0.0 5.5e-08 32.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PSC71514.1 - 0.0071 16.3 0.0 0.019 14.9 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 PSC71514.1 - 0.026 13.9 0.0 0.044 13.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PSC71514.1 - 0.13 11.5 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like PilX PF13681.6 PSC71514.1 - 0.15 12.5 0.1 35 4.9 0.0 3.1 2 1 0 3 3 3 0 Type IV pilus assembly protein PilX C-term Sulfotransfer_1 PF00685.27 PSC71515.1 - 0.03 13.8 0.0 0.053 13.0 0.0 1.5 1 1 0 1 1 1 0 Sulfotransferase domain SRP68 PF16969.5 PSC71516.1 - 1.8e-142 476.2 4.0 2.1e-142 476.0 4.0 1.0 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 Proteasome PF00227.26 PSC71517.1 - 3.7e-42 144.0 0.0 4.1e-42 143.8 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF1754 PF08555.10 PSC71518.1 - 3.2e-05 24.6 2.4 3.2e-05 24.6 2.4 2.4 2 1 0 2 2 2 1 Eukaryotic family of unknown function (DUF1754) Ost4 PF10215.9 PSC71518.1 - 0.0004 20.2 0.1 0.00065 19.5 0.1 1.3 1 0 0 1 1 1 1 Oligosaccaryltransferase PMT2_N PF17987.1 PSC71518.1 - 0.19 11.9 0.0 0.25 11.6 0.0 1.2 1 0 0 1 1 1 0 Phosphoethanolamine N-methyltransferase 2 N-terminal Lyase_1 PF00206.20 PSC71519.1 - 4.8e-117 390.8 0.0 6.9e-117 390.3 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 PSC71519.1 - 1.9e-25 89.0 0.1 3.9e-25 88.0 0.1 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus DUF4288 PF14119.6 PSC71519.1 - 0.19 12.1 0.0 0.37 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) Lyase_1 PF00206.20 PSC71520.1 - 5.8e-117 390.5 0.0 8.2e-117 390.0 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 PSC71520.1 - 1.9e-25 89.0 0.1 4.3e-25 87.9 0.1 1.6 1 0 0 1 1 1 1 Fumarase C C-terminus DUF4288 PF14119.6 PSC71520.1 - 0.2 12.0 0.0 0.4 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4288) FeThRed_A PF02941.15 PSC71521.1 - 2.1e-18 66.2 0.4 2.7e-18 65.8 0.4 1.2 1 0 0 1 1 1 1 Ferredoxin thioredoxin reductase variable alpha chain PRMT5 PF05185.16 PSC71522.1 - 1.5e-69 233.3 0.0 2.2e-69 232.8 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 PSC71522.1 - 6.8e-68 228.6 0.0 1.1e-67 228.0 0.0 1.3 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 PSC71522.1 - 9.4e-54 182.0 0.1 1.3e-53 181.5 0.1 1.2 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 PSC71522.1 - 2.8e-05 24.7 0.0 0.00013 22.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC71522.1 - 0.0068 17.0 0.0 0.016 15.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 PSC71522.1 - 0.019 14.7 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein UPF0020 PF01170.18 PSC71522.1 - 0.13 11.9 0.0 0.22 11.2 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 Amino_oxidase PF01593.24 PSC71524.1 - 4.5e-07 29.5 0.1 6.9e-07 28.9 0.0 1.4 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Trp_halogenase PF04820.14 PSC71524.1 - 0.054 12.3 0.0 0.086 11.7 0.0 1.2 1 0 0 1 1 1 0 Tryptophan halogenase WD40 PF00400.32 PSC71525.1 - 2.6e-19 69.2 9.4 0.00013 22.6 0.2 7.5 7 0 0 7 7 7 4 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 PSC71525.1 - 3.4e-12 46.0 8.3 6.5e-12 45.1 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC71525.1 - 1.1e-09 38.0 8.2 2e-09 37.2 8.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC71525.1 - 1e-08 34.9 4.8 1.8e-08 34.1 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PSC71525.1 - 1.1e-08 35.1 5.3 6.2e-08 32.7 5.4 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 PSC71525.1 - 1.1e-08 34.9 5.5 2.4e-08 33.8 5.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger ANAPC4_WD40 PF12894.7 PSC71525.1 - 3.5e-08 33.6 0.0 0.56 10.5 0.0 4.6 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain zf-RING_2 PF13639.6 PSC71525.1 - 3.6e-08 33.6 6.7 6.7e-08 32.8 6.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PSC71525.1 - 1.4e-07 31.3 7.3 2.7e-07 30.4 7.3 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 PSC71525.1 - 0.00028 21.1 5.8 0.00064 20.0 5.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 PSC71525.1 - 0.0004 20.5 4.6 0.00085 19.4 4.6 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 Prok-RING_4 PF14447.6 PSC71525.1 - 0.002 17.9 5.2 0.0039 17.0 5.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 U-box PF04564.15 PSC71525.1 - 0.004 17.3 0.0 0.0093 16.1 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 PSC71525.1 - 0.0082 15.9 3.0 0.016 15.0 3.0 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 PSC71525.1 - 0.42 10.5 3.1 0.96 9.4 3.1 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 PSC71525.1 - 0.71 9.7 8.8 2.6 7.9 9.0 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 PSC71525.1 - 0.74 9.6 4.4 1.5 8.7 4.4 1.5 1 0 0 1 1 1 0 RING-like zinc finger DZR PF12773.7 PSC71525.1 - 8.2 6.5 7.6 24 5.1 7.6 1.8 1 0 0 1 1 1 0 Double zinc ribbon WD40 PF00400.32 PSC71527.1 - 1.1e-14 54.6 6.8 0.022 15.6 0.1 7.6 8 1 0 8 8 8 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC71527.1 - 6.5e-13 48.8 0.0 5.1e-05 23.5 0.0 5.7 4 2 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PSC71527.1 - 0.011 14.4 0.0 0.018 13.7 0.0 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Glycos_transf_1 PF00534.20 PSC71528.1 - 6e-31 107.3 0.0 1.1e-30 106.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PSC71528.1 - 5.2e-20 72.3 0.0 1.2e-19 71.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 PSC71528.1 - 2.2e-13 50.6 3.7 2.3e-13 50.5 2.3 1.9 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 PSC71528.1 - 1.1e-05 25.9 13.5 1.1e-05 25.9 13.5 4.2 2 1 1 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 PSC71528.1 - 0.00031 21.1 2.0 0.00063 20.1 0.0 2.5 2 1 1 3 3 3 1 Glycosyl transferases group 1 zf-C4H2 PF10146.9 PSC71528.1 - 0.089 13.1 1.2 0.16 12.3 1.2 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein TMF_TATA_bd PF12325.8 PSC71528.1 - 1.5 9.0 14.9 0.4 10.9 6.1 2.8 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding Fez1 PF06818.15 PSC71528.1 - 5.4 7.4 11.3 8.4 6.8 10.7 1.6 1 1 0 1 1 1 0 Fez1 AAA_13 PF13166.6 PSC71528.1 - 6.6 5.2 8.1 7.8 5.0 1.9 2.1 1 1 0 2 2 2 0 AAA domain zf_CCCH_4 PF18345.1 PSC71529.1 - 8.6e-08 32.0 2.9 1.6e-07 31.1 2.9 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 PSC71529.1 - 2e-06 27.6 0.7 3.9e-06 26.6 0.7 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 PSC71529.1 - 0.0002 21.7 1.6 0.00039 20.8 1.6 1.5 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger zf-CCCH_3 PF15663.5 PSC71529.1 - 0.0039 17.4 0.0 0.0039 17.4 0.0 2.7 3 0 0 3 3 3 1 Zinc-finger containing family zf-CCCH_4 PF18044.1 PSC71529.1 - 0.011 15.5 0.7 0.011 15.5 0.7 1.6 2 0 0 2 2 2 0 CCCH-type zinc finger tRNA_anti-codon PF01336.25 PSC71529.1 - 0.059 13.4 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain Med15 PF09606.10 PSC71529.1 - 0.32 9.6 53.1 0.025 13.3 20.2 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal MecA PF05389.12 PSC71529.1 - 3 7.4 8.8 9 5.9 4.2 2.4 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) DUF1980 PF09323.10 PSC71529.1 - 3.2 7.6 8.8 0.94 9.4 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) DUF3801 PF12687.7 PSC71529.1 - 3.3 7.8 16.5 0.95 9.5 4.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) eIF-3_zeta PF05091.12 PSC71529.1 - 7.8 5.4 23.9 1.7 7.5 2.3 2.2 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MatE PF01554.18 PSC71531.1 - 6.3e-58 195.0 25.0 2.9e-33 114.8 2.2 2.9 3 0 0 3 3 3 2 MatE PAC1 PF16094.5 PSC71532.1 - 0.11 11.6 0.0 0.25 10.5 0.0 1.5 2 0 0 2 2 2 0 Proteasome assembly chaperone 4 Exop_C PF18559.1 PSC71533.1 - 0.042 13.7 0.0 0.22 11.4 0.0 1.8 1 1 1 2 2 2 0 Galactose-binding domain-like GTP_EFTU PF00009.27 PSC71534.1 - 5.3e-28 97.9 0.0 8.1e-28 97.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PSC71534.1 - 1.1e-07 31.9 0.0 1.8e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 PSC71534.1 - 1.6e-06 28.4 0.0 1.1e-05 25.7 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RIBIOP_C PF04950.12 PSC71534.1 - 0.00019 21.0 0.1 0.00056 19.4 0.1 1.7 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal SRPRB PF09439.10 PSC71534.1 - 0.0015 18.0 0.1 0.0051 16.3 0.1 1.8 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit cobW PF02492.19 PSC71534.1 - 0.019 14.6 0.2 0.26 10.9 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain PFK PF00365.20 PSC71535.1 - 4.5e-38 131.2 0.3 1.4e-37 129.6 0.1 1.7 2 0 0 2 2 2 1 Phosphofructokinase YdjC PF04794.12 PSC71535.1 - 0.14 12.1 0.0 0.25 11.3 0.0 1.3 1 0 0 1 1 1 0 YdjC-like protein DUF4225 PF13988.6 PSC71535.1 - 0.21 11.1 1.4 15 5.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF4225) Rgp1 PF08737.10 PSC71536.1 - 7e-12 45.2 0.0 2.9e-05 23.4 0.0 3.1 3 0 0 3 3 3 3 Rgp1 Arrestin_N PF00339.29 PSC71536.1 - 0.088 12.9 0.1 1.9 8.6 0.0 2.2 2 0 0 2 2 2 0 Arrestin (or S-antigen), N-terminal domain RL10P_insert PF17777.1 PSC71537.1 - 9e-22 76.9 0.1 1.4e-21 76.3 0.1 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 PSC71537.1 - 2.2e-19 69.4 0.3 4.1e-19 68.6 0.1 1.5 2 0 0 2 2 2 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 PSC71537.1 - 2.8e-18 66.3 7.2 5.6e-18 65.3 7.2 1.5 1 0 0 1 1 1 1 60s Acidic ribosomal protein NadA PF02445.16 PSC71538.1 - 1.9e-31 109.4 1.5 8.7e-31 107.2 0.1 2.0 2 0 0 2 2 2 1 Quinolinate synthetase A protein SufE PF02657.15 PSC71538.1 - 1.2e-27 96.1 0.0 2.8e-27 95.0 0.0 1.7 1 0 0 1 1 1 1 Fe-S metabolism associated domain Exop_C PF18559.1 PSC71539.1 - 0.042 13.7 0.0 0.22 11.4 0.0 1.8 1 1 1 2 2 2 0 Galactose-binding domain-like Trypsin PF00089.26 PSC71540.1 - 7.6e-38 130.5 0.0 7.6e-38 130.5 0.0 1.8 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 PSC71540.1 - 1.5e-05 25.9 0.0 1.5e-05 25.9 0.0 3.9 4 1 0 4 4 4 1 Trypsin-like peptidase domain VSP PF03302.13 PSC71540.1 - 0.0022 16.9 17.1 0.0022 16.9 17.1 2.7 1 1 0 2 2 2 1 Giardia variant-specific surface protein EIF4E-T PF10477.9 PSC71540.1 - 0.052 12.4 19.2 0.073 11.9 19.2 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E TFIIA PF03153.13 PSC71540.1 - 0.24 11.4 51.8 0.026 14.5 44.7 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 PSC71540.1 - 2.3 6.4 32.9 3.6 5.7 32.9 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Trypsin PF00089.26 PSC71541.1 - 7.6e-38 130.5 0.0 7.6e-38 130.5 0.0 1.8 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 PSC71541.1 - 1.5e-05 25.9 0.0 1.5e-05 25.9 0.0 3.9 4 1 0 4 4 4 1 Trypsin-like peptidase domain VSP PF03302.13 PSC71541.1 - 0.0022 16.9 17.1 0.0022 16.9 17.1 2.7 1 1 0 2 2 2 1 Giardia variant-specific surface protein EIF4E-T PF10477.9 PSC71541.1 - 0.052 12.4 19.2 0.072 11.9 19.2 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E TFIIA PF03153.13 PSC71541.1 - 0.49 10.3 52.7 0.035 14.1 45.1 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 PSC71541.1 - 3.4 5.8 33.4 5.2 5.2 33.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Trypsin PF00089.26 PSC71542.1 - 7.3e-38 130.6 0.0 7.3e-38 130.6 0.0 1.8 2 0 0 2 2 2 1 Trypsin Trypsin_2 PF13365.6 PSC71542.1 - 1.5e-05 26.0 0.0 1.5e-05 26.0 0.0 3.9 4 1 0 4 4 4 1 Trypsin-like peptidase domain VSP PF03302.13 PSC71542.1 - 0.0019 17.1 16.9 0.0019 17.1 16.9 2.7 1 1 0 2 2 2 1 Giardia variant-specific surface protein TFIIA PF03153.13 PSC71542.1 - 0.042 13.9 46.2 0.075 13.0 46.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EIF4E-T PF10477.9 PSC71542.1 - 0.074 11.9 19.8 0.1 11.4 19.8 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E SOG2 PF10428.9 PSC71542.1 - 0.11 11.7 17.3 0.17 11.1 17.3 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein PAT1 PF09770.9 PSC71542.1 - 3.5 5.8 33.4 5.1 5.2 33.4 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ICMT PF04140.14 PSC71543.1 - 1.7e-24 86.1 0.0 3.4e-24 85.1 0.0 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 PSC71543.1 - 5.9e-09 36.3 0.2 9.6e-09 35.6 0.2 1.3 1 0 0 1 1 1 1 Phospholipid methyltransferase NnrU PF07298.11 PSC71543.1 - 0.006 16.1 6.5 0.011 15.3 6.5 1.6 1 1 0 1 1 1 1 NnrU protein DUF1295 PF06966.12 PSC71543.1 - 0.056 13.0 0.1 0.077 12.5 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) HrpB1_HrpK PF09613.10 PSC71543.1 - 0.12 12.0 0.1 0.23 11.1 0.1 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) MMR_HSR1 PF01926.23 PSC71545.1 - 1.1e-22 80.3 0.0 1.7e-22 79.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase KH_2 PF07650.17 PSC71545.1 - 2.7e-17 62.3 0.4 4.6e-17 61.6 0.4 1.4 1 0 0 1 1 1 1 KH domain FeoB_N PF02421.18 PSC71545.1 - 2e-12 46.9 0.0 3.3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 PSC71545.1 - 6.6e-09 36.0 0.1 0.00085 19.4 0.0 2.2 1 1 1 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 PSC71545.1 - 1.2e-07 31.8 0.1 0.0036 17.2 0.0 2.4 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PSC71545.1 - 2.8e-07 30.3 0.0 0.011 15.2 0.0 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 PSC71545.1 - 9.2e-05 22.7 0.0 0.00036 20.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 PSC71545.1 - 0.00077 19.1 0.1 0.25 10.9 0.0 2.4 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 PSC71545.1 - 0.0011 18.8 0.0 0.0042 16.8 0.0 2.0 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Arf PF00025.21 PSC71545.1 - 0.0021 17.6 0.1 0.54 9.7 0.0 2.2 2 0 0 2 2 2 2 ADP-ribosylation factor family AIG1 PF04548.16 PSC71545.1 - 0.008 15.5 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 AIG1 family ABC_tran PF00005.27 PSC71545.1 - 0.011 16.3 0.0 0.02 15.4 0.0 1.5 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 PSC71545.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_27 PF13514.6 PSC71545.1 - 0.034 13.7 0.0 0.058 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain MMR_HSR1_Xtn PF16897.5 PSC71545.1 - 0.056 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_18 PF13238.6 PSC71545.1 - 0.064 13.8 0.0 0.34 11.5 0.0 2.2 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 PSC71545.1 - 0.075 12.4 0.1 0.16 11.3 0.0 1.5 1 1 0 1 1 1 0 FtsK/SpoIIIE family TniB PF05621.11 PSC71545.1 - 0.11 11.9 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 PSC71545.1 - 0.12 12.8 1.5 0.66 10.3 0.1 2.4 1 1 1 2 2 2 0 AAA ATPase domain SRPRB PF09439.10 PSC71545.1 - 0.16 11.4 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_28 PF13521.6 PSC71545.1 - 0.17 12.2 0.8 0.37 11.0 0.0 2.1 2 1 0 2 2 2 0 AAA domain Peptidase_M41 PF01434.18 PSC71547.1 - 3e-67 226.2 2.1 4.6e-67 225.6 2.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 PSC71547.1 - 8.1e-44 149.3 0.0 2.2e-43 147.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PSC71547.1 - 7.3e-14 51.3 0.1 1.7e-13 50.2 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 PSC71547.1 - 2.4e-07 30.9 0.0 7.9e-07 29.1 0.0 2.0 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 PSC71547.1 - 5e-06 26.3 0.0 1.5e-05 24.8 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PSC71547.1 - 1.3e-05 25.7 0.8 0.0014 19.0 0.1 3.2 2 1 0 3 3 3 1 AAA ATPase domain TIP49 PF06068.13 PSC71547.1 - 0.00015 21.1 0.0 0.00027 20.3 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 PSC71547.1 - 0.0024 17.6 0.0 0.0062 16.3 0.0 1.7 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_33 PF13671.6 PSC71547.1 - 0.0026 17.9 0.0 0.0058 16.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 PSC71547.1 - 0.0029 17.0 0.4 0.007 15.8 0.4 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 PSC71547.1 - 0.0032 17.8 3.0 0.046 14.0 0.1 3.3 4 0 0 4 4 4 1 AAA domain AAA_7 PF12775.7 PSC71547.1 - 0.004 16.7 0.0 0.015 14.8 0.0 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_28 PF13521.6 PSC71547.1 - 0.008 16.4 1.2 0.055 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 PSC71547.1 - 0.015 15.2 0.1 0.076 12.9 0.1 2.2 2 0 0 2 2 2 0 NACHT domain AAA_2 PF07724.14 PSC71547.1 - 0.021 14.9 0.0 0.082 13.0 0.0 1.9 1 1 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_17 PF13207.6 PSC71547.1 - 0.025 15.0 0.0 0.081 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PSC71547.1 - 0.027 15.0 0.0 0.059 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 PSC71547.1 - 0.031 13.8 0.3 0.28 10.8 0.2 2.4 1 1 1 2 2 2 0 AAA domain TsaE PF02367.17 PSC71547.1 - 0.049 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ABC_tran PF00005.27 PSC71547.1 - 0.054 14.0 0.9 0.26 11.8 0.2 2.5 3 0 0 3 3 3 0 ABC transporter AAA_24 PF13479.6 PSC71547.1 - 0.083 12.6 0.0 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 PSC71547.1 - 0.097 11.9 0.2 0.21 10.8 0.2 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_14 PF13173.6 PSC71547.1 - 0.11 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATP-synt_C PF00137.21 PSC71547.1 - 0.11 12.9 6.2 3.3 8.1 6.5 3.1 3 0 0 3 3 3 0 ATP synthase subunit C Beta_protein PF14350.6 PSC71547.1 - 0.13 11.7 0.0 0.32 10.4 0.0 1.5 2 0 0 2 2 2 0 Beta protein BTB_2 PF02214.22 PSC71548.1 - 1.5e-10 41.2 0.0 2.9e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DUF3095 PF11294.8 PSC71548.1 - 0.0048 16.0 0.3 0.0062 15.6 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3095) CCDC53 PF10152.9 PSC71548.1 - 0.32 11.4 2.2 0.44 11.0 2.2 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex FUSC PF04632.12 PSC71548.1 - 1 7.8 6.3 1.2 7.6 6.3 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family MIF4G PF02854.19 PSC71549.1 - 2.1e-08 34.1 0.0 4.7e-08 32.9 0.0 1.5 2 0 0 2 2 2 1 MIF4G domain zf-C3HC4_3 PF13920.6 PSC71549.1 - 1.8e-07 30.9 7.3 3.1e-07 30.2 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1690 PF07956.11 PSC71549.1 - 0.32 11.4 6.0 0.85 10.0 6.0 1.8 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Prok-RING_4 PF14447.6 PSC71549.1 - 0.87 9.5 10.8 1.6 8.7 10.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 MIF4G PF02854.19 PSC71550.1 - 2.1e-08 34.1 0.0 4.7e-08 32.9 0.0 1.5 2 0 0 2 2 2 1 MIF4G domain zf-C3HC4_3 PF13920.6 PSC71550.1 - 1.8e-07 30.9 7.3 3.1e-07 30.2 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF1690 PF07956.11 PSC71550.1 - 0.32 11.4 6.0 0.85 10.0 6.0 1.8 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) Prok-RING_4 PF14447.6 PSC71550.1 - 0.87 9.5 10.8 1.6 8.7 10.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1289 PF06945.13 PSC71551.1 - 0.087 12.6 0.3 0.16 11.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1289) RcbX PF02341.15 PSC71552.1 - 7.5e-05 23.0 0.1 0.00049 20.3 0.1 2.0 1 1 0 1 1 1 1 RbcX protein PCI PF01399.27 PSC71553.1 - 1.5e-21 76.8 0.0 3.6e-21 75.6 0.0 1.7 1 0 0 1 1 1 1 PCI domain Rpn3_C PF08375.11 PSC71553.1 - 8.5e-21 74.2 0.2 1.8e-20 73.1 0.2 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal TPR_2 PF07719.17 PSC71553.1 - 0.0034 17.4 0.8 0.0034 17.4 0.8 3.5 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 PSC71553.1 - 0.018 15.6 0.8 0.17 12.6 0.8 2.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.28 PSC71553.1 - 1.2 9.0 3.8 0.39 10.6 0.4 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat P34-Arc PF04045.14 PSC71554.1 - 0.0003 20.6 0.0 0.0004 20.2 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc DUF3110 PF11360.8 PSC71555.1 - 9.7e-26 89.8 0.0 1.6e-25 89.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3110) CCDC53 PF10152.9 PSC71555.1 - 0.32 11.4 2.5 0.59 10.5 2.5 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Pex14_N PF04695.13 PSC71555.1 - 4.6 7.9 13.9 1.5 9.5 8.8 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DSBA PF01323.20 PSC71556.1 - 1.2e-28 100.2 0.0 1.4e-28 100.0 0.0 1.1 1 0 0 1 1 1 1 DSBA-like thioredoxin domain Thioredoxin_4 PF13462.6 PSC71556.1 - 3.9e-05 23.9 0.0 0.0026 17.9 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PSC71556.1 - 0.0013 19.2 0.0 0.018 15.5 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Spore_SspJ PF09575.10 PSC71556.1 - 0.054 13.9 0.0 8.3 6.9 0.0 2.6 2 0 0 2 2 2 0 Small spore protein J (Spore_SspJ) PPR_2 PF13041.6 PSC71557.1 - 8.1e-65 214.8 0.0 1.2e-12 47.8 0.0 12.5 5 5 8 13 13 13 10 PPR repeat family PPR PF01535.20 PSC71557.1 - 1.9e-49 162.5 1.4 2.5e-05 24.2 0.0 13.3 13 0 0 13 13 13 11 PPR repeat PPR_3 PF13812.6 PSC71557.1 - 2e-48 162.3 0.0 1.3e-12 47.6 0.0 9.1 4 3 6 10 10 10 6 Pentatricopeptide repeat domain CIA30 PF08547.12 PSC71557.1 - 2.8e-39 134.7 0.0 5.4e-39 133.8 0.0 1.5 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) PPR_1 PF12854.7 PSC71557.1 - 3.6e-36 122.5 0.0 3.7e-05 23.3 0.0 10.8 11 1 0 11 11 11 7 PPR repeat PPR_long PF17177.4 PSC71557.1 - 8.6e-30 103.7 0.0 1.1e-09 38.0 0.0 4.0 2 2 2 4 4 4 3 Pentacotripeptide-repeat region of PRORP NAD_binding_10 PF13460.6 PSC71557.1 - 6.1e-12 45.8 0.6 5e-09 36.3 0.0 5.0 6 0 0 6 6 6 2 NAD(P)H-binding NmrA PF05368.13 PSC71557.1 - 0.0021 17.6 1.1 0.0057 16.2 0.4 2.1 3 0 0 3 3 3 1 NmrA-like family Epimerase PF01370.21 PSC71557.1 - 0.013 15.0 0.1 0.031 13.8 0.1 1.6 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 PSC71557.1 - 0.05 13.7 0.2 0.14 12.2 0.2 1.8 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus CBM_11 PF03425.13 PSC71557.1 - 0.072 13.0 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Carbohydrate binding domain (family 11) ATP13 PF12921.7 PSC71557.1 - 0.15 12.0 0.0 13 5.6 0.0 3.8 4 1 1 5 5 5 0 Mitochondrial ATPase expression TPR_7 PF13176.6 PSC71557.1 - 0.65 10.2 5.2 58 4.1 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat RcbX PF02341.15 PSC71558.1 - 7.1e-05 23.0 0.1 0.00056 20.2 0.1 2.1 1 1 0 1 1 1 1 RbcX protein Fer4 PF00037.27 PSC71559.1 - 1.7e-14 53.0 16.0 1.9e-08 33.8 4.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 PSC71559.1 - 4.1e-13 49.7 10.6 6.6e-13 49.0 10.6 1.3 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 PSC71559.1 - 1.6e-10 41.8 5.3 0.0001 23.1 0.1 2.3 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 PSC71559.1 - 6.3e-09 35.8 32.1 6.7e-06 26.1 12.4 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_10 PF13237.6 PSC71559.1 - 7.8e-09 35.5 21.0 1.7e-06 28.0 12.6 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 PSC71559.1 - 2.3e-08 34.1 10.7 3.8e-08 33.4 10.7 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 PSC71559.1 - 4e-07 30.4 18.0 0.00033 21.0 11.1 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 PSC71559.1 - 4.2e-07 29.8 17.8 0.00043 20.2 5.4 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_2 PF12797.7 PSC71559.1 - 6.9e-07 29.0 11.7 0.003 17.6 2.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 PSC71559.1 - 4.1e-06 26.9 10.4 0.00033 20.9 1.9 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 PSC71559.1 - 0.0011 19.4 12.5 0.086 13.4 13.3 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 PSC71559.1 - 0.016 15.5 6.6 0.33 11.2 0.4 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain Fer4_13 PF13370.6 PSC71559.1 - 0.016 15.7 14.7 0.76 10.4 2.7 2.6 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 PSC71559.1 - 0.021 15.0 8.8 0.9 9.8 1.5 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain ETF_QO PF05187.13 PSC71559.1 - 0.049 13.8 5.8 0.2 11.8 0.6 2.2 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_3 PF12798.7 PSC71559.1 - 0.21 12.6 16.3 0.37 11.8 4.1 2.4 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_22 PF17179.4 PSC71559.1 - 0.52 11.2 12.0 3.1 8.7 2.2 2.2 1 1 1 2 2 2 0 4Fe-4S dicluster domain GARS_A PF01071.19 PSC71561.1 - 4.6e-78 261.5 0.0 6.5e-78 261.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 PSC71561.1 - 6.3e-35 119.8 0.0 1.3e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 PSC71561.1 - 2.8e-28 98.0 4.5 3.3e-28 97.8 0.2 3.0 3 1 0 3 3 3 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp PF02222.22 PSC71561.1 - 3.7e-06 26.6 0.0 6.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 PSC71561.1 - 7.5e-05 22.3 0.2 0.00014 21.4 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 PSC71561.1 - 0.00014 21.5 0.0 0.00028 20.6 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 PSC71561.1 - 0.00083 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.10 PSC71561.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 PSC71561.1 - 0.013 15.0 0.1 0.032 13.7 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain RWP-RK PF02042.15 PSC71561.1 - 0.022 14.7 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 RWP-RK domain ATP-grasp_3 PF02655.14 PSC71561.1 - 0.036 14.1 0.0 0.092 12.8 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 PSC71561.1 - 0.039 13.5 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus GARS_A PF01071.19 PSC71562.1 - 4.6e-78 261.5 0.0 6.5e-78 261.0 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.15 PSC71562.1 - 6.3e-35 119.8 0.0 1.3e-34 118.8 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 PSC71562.1 - 2.8e-28 98.0 4.5 3.3e-28 97.8 0.2 3.0 3 1 0 3 3 3 1 Phosphoribosylglycinamide synthetase, C domain ATP-grasp PF02222.22 PSC71562.1 - 3.7e-06 26.6 0.0 6.6e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 PSC71562.1 - 7.5e-05 22.3 0.2 0.00014 21.4 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 PSC71562.1 - 0.00014 21.5 0.0 0.00028 20.6 0.0 1.4 1 0 0 1 1 1 1 RimK-like ATP-grasp domain ATP-grasp_4 PF13535.6 PSC71562.1 - 0.00083 19.0 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_2 PF08442.10 PSC71562.1 - 0.0011 18.6 0.0 0.0019 17.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp_5 PF13549.6 PSC71562.1 - 0.013 15.0 0.1 0.032 13.7 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain RWP-RK PF02042.15 PSC71562.1 - 0.022 14.7 0.0 0.046 13.7 0.0 1.5 1 0 0 1 1 1 0 RWP-RK domain ATP-grasp_3 PF02655.14 PSC71562.1 - 0.036 14.1 0.0 0.092 12.8 0.0 1.7 2 0 0 2 2 2 0 ATP-grasp domain Dala_Dala_lig_C PF07478.13 PSC71562.1 - 0.039 13.5 0.0 0.061 12.8 0.0 1.3 1 0 0 1 1 1 0 D-ala D-ala ligase C-terminus LigB PF02900.18 PSC71563.1 - 4e-37 127.8 0.0 4.9e-37 127.5 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Pkinase_Tyr PF07714.17 PSC71564.1 - 2.1e-79 266.5 0.0 8.4e-25 87.5 0.0 4.5 4 1 0 4 4 4 4 Protein tyrosine kinase Pkinase PF00069.25 PSC71564.1 - 2.9e-75 253.0 0.0 2.1e-23 83.0 0.0 4.2 4 0 0 4 4 4 4 Protein kinase domain APH PF01636.23 PSC71564.1 - 1e-07 32.2 3.8 0.0037 17.2 0.3 3.1 2 1 0 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PSC71564.1 - 3.9e-05 22.6 0.0 0.23 10.2 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase Haspin_kinase PF12330.8 PSC71564.1 - 0.0048 15.9 0.1 1.2 8.0 0.0 2.1 2 0 0 2 2 2 2 Haspin like kinase domain DUF3142 PF11340.8 PSC71564.1 - 0.028 14.3 0.1 1.6 8.5 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3142) Kdo PF06293.14 PSC71564.1 - 0.043 13.2 1.9 0.53 9.6 0.0 3.0 4 0 0 4 4 4 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_S4e PF00900.20 PSC71565.1 - 2.1e-39 133.3 0.8 1.4e-36 124.2 0.1 2.3 2 0 0 2 2 2 2 Ribosomal family S4e 40S_S4_C PF16121.5 PSC71565.1 - 6.1e-23 80.2 0.0 1.2e-22 79.3 0.0 1.4 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 PSC71565.1 - 2.5e-21 75.5 7.8 5.8e-21 74.3 7.8 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.25 PSC71565.1 - 7.2e-07 28.8 0.0 1.6e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 PSC71565.1 - 0.00017 21.4 1.5 0.00017 21.4 1.5 2.5 3 0 0 3 3 3 1 KOW motif LON_substr_bdg PF02190.16 PSC71566.1 - 2.7e-10 40.5 0.0 4.2e-10 39.8 0.0 1.3 1 1 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Hydant_A_N PF05378.13 PSC71566.1 - 0.055 13.2 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region TauE PF01925.19 PSC71567.1 - 8.5e-26 91.0 64.7 1.4e-11 44.5 19.0 2.6 1 1 2 3 3 3 3 Sulfite exporter TauE/SafE SARAF PF06682.12 PSC71567.1 - 0.0026 17.5 0.5 0.032 13.9 0.5 2.1 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis CoA_binding_3 PF13727.6 PSC71567.1 - 0.0071 16.4 5.9 0.68 9.9 1.8 3.1 3 0 0 3 3 3 2 CoA-binding domain DUF1180 PF06679.12 PSC71567.1 - 0.94 9.9 10.7 0.17 12.3 1.7 3.2 3 1 1 4 4 4 0 Protein of unknown function (DUF1180) Pex14_N PF04695.13 PSC71567.1 - 2.6 8.7 10.1 1.7 9.3 4.1 2.8 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UQ_con PF00179.26 PSC71568.1 - 1.1e-19 70.5 0.0 1.6e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 PSC71568.1 - 0.0042 16.9 0.0 0.007 16.2 0.0 1.3 1 0 0 1 1 1 1 UEV domain TFIIA PF03153.13 PSC71568.1 - 0.13 12.3 21.2 0.23 11.4 6.0 2.4 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit CCT PF06203.14 PSC71569.1 - 4.9e-10 39.3 9.9 8e-10 38.6 9.9 1.3 1 0 0 1 1 1 1 CCT motif zf-B_box PF00643.24 PSC71569.1 - 2.5e-07 30.7 0.8 6.1e-07 29.5 0.8 1.7 1 0 0 1 1 1 1 B-box zinc finger RRM_1 PF00076.22 PSC71570.1 - 4.3e-13 48.9 0.0 9.6e-13 47.8 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lsm_interact PF05391.11 PSC71570.1 - 5.8e-05 22.4 0.8 0.00014 21.2 0.8 1.7 1 0 0 1 1 1 1 Lsm interaction motif TPR_14 PF13428.6 PSC71570.1 - 0.017 15.9 0.1 0.017 15.9 0.1 8.6 8 1 2 10 10 10 0 Tetratricopeptide repeat MOSP_C PF02722.15 PSC71570.1 - 0.12 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Major Outer Sheath Protein C-terminal domain Presenilin PF01080.17 PSC71570.1 - 0.2 10.4 11.8 0.34 9.6 11.8 1.3 1 0 0 1 1 1 0 Presenilin DUF572 PF04502.13 PSC71570.1 - 0.37 10.4 12.1 0.72 9.4 12.1 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) TFIIA PF03153.13 PSC71570.1 - 4.6 7.1 43.1 0.14 12.1 32.8 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 PSC71570.1 - 9.8 4.7 13.9 14 4.2 13.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Gln-synt_C PF00120.24 PSC71571.1 - 8.6e-15 54.6 0.0 1.3e-13 50.7 0.0 2.0 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.19 PSC71571.1 - 4.6e-10 39.1 0.0 1.1e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain SPA PF08616.10 PSC71572.1 - 0.0018 18.2 0.0 0.0033 17.4 0.0 1.3 1 0 0 1 1 1 1 Stabilization of polarity axis Ndr PF03096.14 PSC71573.1 - 1.8e-57 194.2 0.0 3e-57 193.5 0.0 1.3 1 0 0 1 1 1 1 Ndr family C2 PF00168.30 PSC71573.1 - 1.1e-21 77.0 0.0 9.4e-18 64.4 0.0 2.6 2 0 0 2 2 2 2 C2 domain Thioredoxin PF00085.20 PSC71573.1 - 8.7e-13 48.2 0.0 7.8e-06 25.8 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin HyaE PF07449.11 PSC71573.1 - 0.0056 16.6 0.1 0.42 10.6 0.1 2.6 2 0 0 2 2 2 1 Hydrogenase-1 expression protein HyaE TFIIA PF03153.13 PSC71573.1 - 0.012 15.6 4.7 0.024 14.7 4.7 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 PSC71573.1 - 0.024 13.6 3.1 0.035 13.0 3.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Hydrolase_4 PF12146.8 PSC71573.1 - 0.078 12.2 0.0 0.17 11.1 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioredoxin_2 PF13098.6 PSC71573.1 - 0.13 12.7 0.0 7.6 7.0 0.0 2.5 2 0 0 2 2 2 0 Thioredoxin-like domain BRF1 PF07741.13 PSC71573.1 - 3.5 8.0 8.0 14 6.1 1.5 2.6 2 0 0 2 2 2 0 Brf1-like TBP-binding domain Cys_Met_Meta_PP PF01053.20 PSC71575.1 - 3e-139 463.8 0.0 3.6e-139 463.6 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 PSC71575.1 - 6.3e-05 22.5 0.6 0.00011 21.7 0.6 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 PSC71575.1 - 6.3e-05 22.1 0.2 0.00012 21.2 0.2 1.4 1 0 0 1 1 1 1 Aminotransferase class-V GDC-P PF02347.16 PSC71575.1 - 0.00015 20.8 0.1 0.00028 19.9 0.1 1.4 1 0 0 1 1 1 1 Glycine cleavage system P-protein Aminotran_1_2 PF00155.21 PSC71575.1 - 0.00022 20.5 0.0 0.00037 19.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Met_gamma_lyase PF06838.11 PSC71575.1 - 0.067 11.7 0.0 0.12 10.8 0.0 1.4 1 0 0 1 1 1 0 Methionine gamma-lyase Cecropin PF00272.19 PSC71575.1 - 0.084 12.6 0.0 0.22 11.2 0.0 1.7 1 0 0 1 1 1 0 Cecropin family HECT PF00632.25 PSC71576.1 - 1e-87 294.5 0.0 1.9e-87 293.6 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 PSC71576.1 - 1.3e-70 233.8 19.5 8.8e-13 48.7 0.0 8.6 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat Peptidase_C1 PF00112.23 PSC71576.1 - 1.2e-55 189.0 11.0 1.8e-55 188.4 11.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease RCC1_2 PF13540.6 PSC71576.1 - 1.2e-38 130.2 39.8 4.5e-07 29.5 0.9 8.2 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Peptidase_C1_2 PF03051.15 PSC71576.1 - 7.1e-06 25.1 3.9 0.0031 16.3 0.8 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Inhibitor_I29 PF08246.12 PSC71576.1 - 6e-05 23.4 1.0 0.00011 22.6 1.0 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) UBA PF00627.31 PSC71576.1 - 0.0051 16.7 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain HECT PF00632.25 PSC71577.1 - 1e-87 294.5 0.0 1.9e-87 293.6 0.0 1.5 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 PSC71577.1 - 1.3e-70 233.8 19.5 8.7e-13 48.7 0.0 8.6 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat Peptidase_C1 PF00112.23 PSC71577.1 - 1.2e-55 189.0 11.0 1.8e-55 188.4 11.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease RCC1_2 PF13540.6 PSC71577.1 - 1.1e-38 130.2 39.8 4.5e-07 29.5 0.9 8.2 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Peptidase_C1_2 PF03051.15 PSC71577.1 - 7.1e-06 25.1 3.9 0.0031 16.3 0.8 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Inhibitor_I29 PF08246.12 PSC71577.1 - 6e-05 23.4 1.0 0.00011 22.6 1.0 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) UBA PF00627.31 PSC71577.1 - 0.0051 16.7 0.1 0.011 15.6 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UvrD-helicase PF00580.21 PSC71578.1 - 6.4e-32 111.3 8.9 3.7e-23 82.5 4.2 3.3 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 PSC71578.1 - 1.2e-22 80.8 0.0 1.3e-13 51.1 0.0 3.5 4 0 0 4 4 4 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 PSC71578.1 - 1.1e-14 55.0 0.0 1.1e-09 38.7 0.1 2.7 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 PSC71578.1 - 7.1e-08 32.2 0.1 0.00079 19.2 0.0 2.7 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 PSC71578.1 - 0.12 12.1 3.7 32 4.1 0.0 4.4 5 0 0 5 5 5 0 Viral (Superfamily 1) RNA helicase Vac7 PF12751.7 PSC71578.1 - 1.5 8.1 7.7 4.9 6.5 7.7 1.8 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 UvrD-helicase PF00580.21 PSC71579.1 - 6.4e-32 111.3 8.9 3.7e-23 82.5 4.2 3.3 3 0 0 3 3 3 2 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 PSC71579.1 - 8.8e-24 84.5 0.0 9.8e-15 54.8 0.0 3.5 4 0 0 4 4 4 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 PSC71579.1 - 1.1e-14 55.0 0.0 1.1e-09 38.7 0.1 2.7 2 0 0 2 2 2 2 AAA domain UvrD_C_2 PF13538.6 PSC71579.1 - 7e-08 32.2 0.1 0.00079 19.2 0.0 2.7 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 PSC71579.1 - 0.16 11.7 4.1 32 4.1 0.0 4.4 5 0 0 5 5 5 0 Viral (Superfamily 1) RNA helicase Vac7 PF12751.7 PSC71579.1 - 1.5 8.1 7.7 4.8 6.5 7.7 1.8 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Peptidase_M41 PF01434.18 PSC71580.1 - 4.2e-64 215.9 0.0 4.2e-64 215.9 0.0 2.2 2 0 0 2 2 2 1 Peptidase family M41 AAA PF00004.29 PSC71580.1 - 6.1e-41 139.9 0.0 1.6e-40 138.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sec20 PF03908.13 PSC71580.1 - 4.7e-14 52.1 0.1 2e-13 50.0 0.0 2.1 2 0 0 2 2 2 1 Sec20 AAA_lid_3 PF17862.1 PSC71580.1 - 3.1e-10 39.7 0.2 1.3e-09 37.7 0.2 2.1 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 PSC71580.1 - 0.00036 20.5 0.0 0.0011 18.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) FtsH_ext PF06480.15 PSC71580.1 - 0.00038 20.8 0.0 0.0034 17.7 0.0 2.3 1 1 0 1 1 1 1 FtsH Extracellular AAA_22 PF13401.6 PSC71580.1 - 0.0032 17.8 0.4 0.52 10.6 0.1 3.2 3 0 0 3 3 3 1 AAA domain TIP49 PF06068.13 PSC71580.1 - 0.0059 15.9 0.0 0.01 15.1 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 PSC71580.1 - 0.0069 16.1 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 PSC71580.1 - 0.059 13.5 0.1 0.18 11.9 0.0 1.8 2 0 0 2 2 1 0 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 PSC71580.1 - 0.091 12.9 0.0 0.091 12.9 0.0 2.6 3 0 0 3 3 3 0 AAA domain BAF1_ABF1 PF04684.13 PSC71580.1 - 6.6 5.7 7.5 13 4.7 7.5 1.4 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor EF-hand_1 PF00036.32 PSC71581.1 - 0.00025 20.3 0.0 0.00052 19.4 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 PSC71581.1 - 0.0006 19.2 0.0 0.0012 18.3 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 PSC71581.1 - 0.032 14.2 0.0 0.077 13.0 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 PSC71581.1 - 0.041 14.3 0.0 0.072 13.6 0.0 1.4 1 0 0 1 1 1 0 EF-hand domain pair SBP_bac_3 PF00497.20 PSC71582.1 - 9e-10 38.3 0.0 2e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 Bacterial extracellular solute-binding proteins, family 3 Pox_MCEL PF03291.16 PSC71583.1 - 8.2e-31 107.3 0.0 1.6e-30 106.4 0.0 1.4 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 PSC71583.1 - 1.8e-11 44.6 0.0 3.7e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC71583.1 - 1.9e-09 38.2 0.0 7.4e-09 36.3 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC71583.1 - 2.9e-08 33.7 0.0 5.1e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC71583.1 - 4.6e-08 33.6 0.0 9.6e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC71583.1 - 8.3e-07 29.0 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 PSC71583.1 - 0.14 11.4 0.0 0.26 10.5 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase MgtE PF01769.16 PSC71584.1 - 2e-19 70.2 6.6 2.9e-19 69.7 6.6 1.2 1 0 0 1 1 1 1 Divalent cation transporter Red1 PF07964.11 PSC71585.1 - 0.18 10.0 0.0 0.22 9.7 0.0 1.0 1 0 0 1 1 1 0 Rec10 / Red1 Peptidase_M16_C PF05193.21 PSC71586.1 - 8.4e-48 162.8 0.0 1.5e-23 83.8 0.0 2.7 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 PSC71586.1 - 3.5e-23 82.2 0.0 9.9e-20 71.0 0.0 2.4 2 0 0 2 2 2 2 Insulinase (Peptidase family M16) DUF1631 PF07793.11 PSC71586.1 - 0.74 8.2 5.3 1.4 7.2 5.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) zf-C3HC PF07967.13 PSC71587.1 - 3.1e-27 95.2 0.1 1.1e-26 93.4 0.0 1.9 2 0 0 2 2 2 1 C3HC zinc finger-like Lactamase_B PF00753.27 PSC71587.1 - 1.8e-15 57.5 0.5 4e-15 56.4 0.5 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PSC71587.1 - 5.6e-07 29.3 0.0 1.1e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Rsm1 PF08600.10 PSC71587.1 - 4.6e-06 26.7 0.0 0.41 10.8 0.0 3.8 3 1 0 3 3 3 2 Rsm1-like Lactamase_B_6 PF16661.5 PSC71587.1 - 0.0024 17.4 0.0 0.0043 16.5 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain zf-C3HC4 PF00097.25 PSC71588.1 - 6.8e-07 29.1 6.1 1.2e-06 28.2 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PSC71588.1 - 9.8e-06 25.3 7.6 1.8e-05 24.4 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 PSC71588.1 - 3.9e-05 23.4 1.5 7.9e-05 22.4 1.5 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 PSC71588.1 - 5.9e-05 22.8 4.5 0.00011 22.0 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) BRCT PF00533.26 PSC71588.1 - 0.00026 21.3 0.0 0.00057 20.2 0.0 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain zf-RING_2 PF13639.6 PSC71588.1 - 0.0011 19.3 6.7 0.002 18.4 6.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 PSC71588.1 - 0.0018 18.2 8.4 0.0046 16.9 8.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PSC71588.1 - 0.0066 16.6 8.5 0.013 15.6 8.5 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING BRCT_2 PF16589.5 PSC71588.1 - 0.0078 16.6 0.0 0.038 14.4 0.0 2.1 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain zf-RING_5 PF14634.6 PSC71588.1 - 0.0081 16.1 5.9 0.035 14.1 6.1 2.0 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PSC71588.1 - 0.041 13.8 6.7 0.23 11.3 6.9 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 RTT107_BRCT_5 PF16770.5 PSC71588.1 - 0.048 13.6 0.0 0.098 12.5 0.0 1.5 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain zf-MIZ PF02891.20 PSC71588.1 - 0.13 12.0 3.9 0.33 10.7 3.9 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-Nse PF11789.8 PSC71588.1 - 0.66 9.8 2.6 1.1 9.1 2.6 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit IBR PF01485.21 PSC71588.1 - 0.81 10.0 4.7 3.4 8.0 4.6 2.1 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_4 PF14570.6 PSC71588.1 - 1.1 9.1 5.9 2.5 8.0 5.9 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 PSC71588.1 - 1.1 9.6 4.2 4.6 7.6 4.2 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain ShK PF01549.24 PSC71589.1 - 0.31 11.6 19.4 0.2 12.2 4.3 3.0 2 1 1 3 3 3 0 ShK domain-like DUF1450 PF07293.11 PSC71589.1 - 9.5 6.1 8.4 6.4 6.7 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1450) Sad1_UNC PF07738.13 PSC71590.1 - 1.7e-16 60.4 0.0 3.1e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal Pkinase PF00069.25 PSC71591.1 - 2.4e-69 233.6 0.0 3.7e-69 233.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC71591.1 - 5.4e-36 124.2 0.0 8.6e-36 123.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase NAF PF03822.14 PSC71591.1 - 2.5e-14 53.2 0.1 3.3e-06 27.2 0.0 2.5 2 0 0 2 2 2 2 NAF domain WD40 PF00400.32 PSC71591.1 - 2.5e-14 53.4 0.1 6.9e-05 23.5 0.0 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC71591.1 - 1.3e-07 31.8 0.0 0.21 11.9 0.0 5.1 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Kinase-like PF14531.6 PSC71591.1 - 1.6e-07 31.0 0.0 3.4e-07 29.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like KA1 PF02149.19 PSC71591.1 - 0.0069 16.2 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 1 Kinase associated domain 1 Kdo PF06293.14 PSC71591.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Frtz PF11768.8 PSC71591.1 - 0.095 11.0 0.0 4.7 5.4 0.0 2.1 2 0 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz ABC1 PF03109.16 PSC71592.1 - 1.9e-31 108.7 0.0 3.2e-31 108.0 0.0 1.4 1 0 0 1 1 1 1 ABC1 family TFCD_C PF12612.8 PSC71593.1 - 3.2e-30 105.4 0.0 1.4e-29 103.3 0.0 2.2 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal WD40 PF00400.32 PSC71593.1 - 9e-20 70.6 18.4 0.0058 17.5 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat HEAT PF02985.22 PSC71593.1 - 7.5e-05 22.7 30.3 0.42 11.0 0.0 10.1 11 0 0 11 11 11 3 HEAT repeat ANAPC4_WD40 PF12894.7 PSC71593.1 - 0.047 14.0 0.0 1.2e+02 3.1 0.0 4.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PSC71593.1 - 0.063 12.2 0.0 4.4 6.2 0.0 2.8 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1918 PF08940.11 PSC71593.1 - 0.096 12.3 0.1 0.46 10.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1918) zf-C3HC4_3 PF13920.6 PSC71594.1 - 2.6e-08 33.6 14.5 2.6e-08 33.6 14.5 2.5 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC71594.1 - 0.00037 20.8 17.6 0.00037 20.8 17.6 2.1 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 PSC71594.1 - 0.0017 18.1 14.6 0.0017 18.1 14.6 2.8 3 0 0 3 3 3 1 Prokaryotic RING finger family 4 ATG16 PF08614.11 PSC71594.1 - 0.0075 16.5 13.3 0.0075 16.5 13.3 2.4 2 1 0 2 2 2 1 Autophagy protein 16 (ATG16) KELK PF15796.5 PSC71594.1 - 0.02 15.3 10.3 0.02 15.3 10.3 1.9 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase Seryl_tRNA_N PF02403.22 PSC71594.1 - 0.071 13.4 4.3 0.18 12.0 4.3 1.6 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain NumbF PF06311.12 PSC71594.1 - 3.6 8.2 8.7 0.14 12.8 2.0 2.1 2 1 0 2 2 2 0 NUMB domain RisS_PPD PF16524.5 PSC71594.1 - 3.7 7.8 5.2 2.1 8.6 0.3 2.6 2 1 1 3 3 3 0 Periplasmic domain of Sensor histidine kinase RisS zf-RING_5 PF14634.6 PSC71594.1 - 5.4 7.0 24.1 0.39 10.7 17.2 2.6 3 1 0 3 3 3 0 zinc-RING finger domain KLRAQ PF10205.9 PSC71594.1 - 9.7 6.5 13.1 0.3 11.3 6.8 1.7 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein La PF05383.17 PSC71595.1 - 1.5e-16 60.2 0.0 2.5e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 La domain HARE-HTH PF05066.13 PSC71595.1 - 1.1e-10 41.7 0.0 2.1e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain CPSase_L_D2 PF02786.17 PSC71596.1 - 8.5e-83 277.0 0.0 1.5e-82 276.2 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 PSC71596.1 - 3.9e-45 152.9 0.0 9.5e-45 151.7 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 PSC71596.1 - 6.2e-39 132.4 0.0 1.5e-38 131.2 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp PF02222.22 PSC71596.1 - 8.7e-08 31.9 0.0 2.1e-07 30.7 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 PSC71596.1 - 6.2e-05 22.6 0.0 0.00016 21.3 0.0 1.7 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus RimK PF08443.11 PSC71596.1 - 0.00048 19.8 0.0 0.0013 18.3 0.0 1.7 1 1 0 1 1 1 1 RimK-like ATP-grasp domain Oxidored_nitro PF00148.19 PSC71596.1 - 0.002 16.9 0.1 0.0032 16.3 0.1 1.2 1 0 0 1 1 1 1 Nitrogenase component 1 type Oxidoreductase ATPgrasp_Ter PF15632.6 PSC71596.1 - 0.024 14.4 0.0 0.054 13.2 0.0 1.6 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon DUF4505 PF14956.6 PSC71596.1 - 0.032 14.0 0.0 0.053 13.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) ATP-grasp_3 PF02655.14 PSC71596.1 - 0.15 12.1 0.0 0.52 10.4 0.0 1.9 1 1 0 1 1 1 0 ATP-grasp domain FA_desaturase PF00487.24 PSC71597.1 - 2.2e-16 60.5 25.5 3.6e-16 59.8 25.5 1.4 1 0 0 1 1 1 1 Fatty acid desaturase Cytochrome_CBB3 PF13442.6 PSC71599.1 - 1.3e-10 41.4 0.0 5.3e-10 39.5 0.0 2.1 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III LRR_9 PF14580.6 PSC71599.1 - 0.0002 20.9 0.0 0.00054 19.5 0.0 1.6 1 0 0 1 1 1 1 Leucine-rich repeat Cytochrom_C550 PF14495.6 PSC71599.1 - 0.023 14.4 0.0 0.063 13.0 0.0 1.7 1 0 0 1 1 1 0 Cytochrome c-550 domain Cytochrom_C PF00034.21 PSC71599.1 - 0.059 14.5 0.1 0.059 14.5 0.1 4.0 2 1 0 2 2 2 0 Cytochrome c LURAP PF14854.6 PSC71599.1 - 0.19 11.7 4.6 0.063 13.2 0.4 2.4 2 0 0 2 2 2 0 Leucine rich adaptor protein Jas PF16135.5 PSC71600.1 - 2.2e-20 72.6 0.6 6.2e-11 42.3 0.0 2.8 2 0 0 2 2 2 2 TPL-binding domain in jasmonate signalling PHD PF00628.29 PSC71600.1 - 6.5e-07 29.1 40.5 9.4e-06 25.4 14.2 3.2 3 0 0 3 3 3 2 PHD-finger FR47 PF08445.10 PSC71600.1 - 0.17 11.9 0.0 0.51 10.4 0.0 1.8 1 0 0 1 1 1 0 FR47-like protein Pox_MCEL PF03291.16 PSC71601.1 - 8.2e-31 107.3 0.0 1.6e-30 106.4 0.0 1.4 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_25 PF13649.6 PSC71601.1 - 1.8e-11 44.6 0.0 3.7e-11 43.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC71601.1 - 1.9e-09 38.2 0.0 7.4e-09 36.3 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC71601.1 - 2.9e-08 33.7 0.0 5.1e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC71601.1 - 4.6e-08 33.6 0.0 9.6e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC71601.1 - 8.3e-07 29.0 0.0 1.7e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 PSC71601.1 - 0.14 11.4 0.0 0.26 10.5 0.0 1.5 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase ADH_zinc_N_2 PF13602.6 PSC71602.1 - 8.1e-28 98.1 0.1 1.6e-27 97.2 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 PSC71602.1 - 5.4e-13 49.1 0.5 1.1e-12 48.0 0.1 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PSC71602.1 - 4e-06 26.7 0.0 0.00024 20.9 0.0 3.0 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.12 PSC71602.1 - 0.022 15.4 0.1 0.048 14.3 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain TrkA_N PF02254.18 PSC71602.1 - 0.027 14.7 0.1 0.13 12.5 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain YAcAr PF10686.9 PSC71602.1 - 0.076 13.0 0.3 0.25 11.3 0.3 1.9 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family Glyco_hydro_4C PF11975.8 PSC71602.1 - 0.15 12.1 0.0 0.28 11.2 0.0 1.3 1 1 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain ADH_N_2 PF16884.5 PSC71602.1 - 0.15 11.9 0.1 0.51 10.2 0.1 1.8 1 1 0 1 1 1 0 N-terminal domain of oxidoreductase DUF819 PF05684.12 PSC71603.1 - 1.1e-57 195.8 27.5 1.6e-57 195.3 27.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF819) CAP PF00188.26 PSC71604.1 - 2.4e-22 80.1 4.2 2.4e-22 80.1 4.2 2.3 2 0 0 2 2 2 1 Cysteine-rich secretory protein family SAP PF02037.27 PSC71604.1 - 6.6e-07 28.9 0.1 6.6e-07 28.9 0.1 1.7 2 0 0 2 2 2 1 SAP domain DDA1 PF10172.9 PSC71604.1 - 0.0027 17.9 0.0 0.0052 17.0 0.0 1.5 1 0 0 1 1 1 1 Det1 complexing ubiquitin ligase Snf7 PF03357.21 PSC71605.1 - 3.4e-35 121.2 15.1 3.4e-35 121.2 15.1 1.6 2 0 0 2 2 2 1 Snf7 WBS_methylT PF12589.8 PSC71605.1 - 6.8e-17 62.0 4.7 6.8e-17 62.0 4.7 2.4 2 1 1 3 3 3 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 PSC71605.1 - 1.1e-10 42.0 0.1 3.9e-10 40.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC71605.1 - 1.8e-09 38.2 0.1 1.8e-08 35.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC71605.1 - 3e-05 24.7 0.3 0.00014 22.5 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC71605.1 - 0.00068 19.5 0.0 0.0032 17.3 0.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC71605.1 - 0.0029 17.4 0.3 0.015 15.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain RPW8 PF05659.11 PSC71605.1 - 0.87 9.3 9.1 0.21 11.2 4.2 2.1 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Tweety PF04906.13 PSC71605.1 - 4.6 5.8 4.7 6.6 5.3 4.7 1.3 1 0 0 1 1 1 0 Tweety YccV-like PF08755.11 PSC71606.1 - 5.2e-23 81.4 0.0 8.8e-23 80.7 0.0 1.4 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like TCR PF03638.15 PSC71607.1 - 2.9e-24 85.1 47.3 4.9e-12 45.9 17.8 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain PP-binding PF00550.25 PSC71607.1 - 6.7e-13 48.8 1.1 1.5e-12 47.7 1.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 PSC71607.1 - 1.4e-05 25.3 0.9 2.4e-05 24.5 0.9 1.4 1 0 0 1 1 1 1 Acyl-carrier Ank_2 PF12796.7 PSC71608.1 - 1e-22 80.5 0.0 1.1e-07 32.3 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC71608.1 - 1.4e-20 73.4 3.6 3.4e-06 27.5 0.1 6.3 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC71608.1 - 5.8e-15 55.2 8.8 0.0051 17.1 0.3 6.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC71608.1 - 3.8e-12 45.2 5.4 0.0023 18.3 0.0 7.6 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 PSC71608.1 - 9e-09 35.4 7.4 0.0042 17.5 0.0 6.6 6 0 0 6 6 6 2 Ankyrin repeat AAA_19 PF13245.6 PSC71608.1 - 0.043 14.2 0.0 0.26 11.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PSC71608.1 - 0.077 13.3 0.0 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Ank_2 PF12796.7 PSC71609.1 - 1e-22 80.5 0.0 1.1e-07 32.3 0.0 4.8 3 1 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC71609.1 - 1.4e-20 73.4 3.6 3.4e-06 27.5 0.1 6.3 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC71609.1 - 5.8e-15 55.2 8.8 0.0051 17.1 0.3 6.3 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC71609.1 - 3.8e-12 45.3 5.4 0.0023 18.3 0.0 7.6 8 0 0 8 8 8 3 Ankyrin repeat Ank PF00023.30 PSC71609.1 - 9e-09 35.4 7.4 0.0042 17.5 0.0 6.6 6 0 0 6 6 6 2 Ankyrin repeat AAA_19 PF13245.6 PSC71609.1 - 0.042 14.2 0.0 0.26 11.6 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PSC71609.1 - 0.077 13.3 0.0 1.3 9.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain Pkinase PF00069.25 PSC71610.1 - 4.5e-67 226.2 0.0 5.4e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC71610.1 - 5.6e-27 94.6 0.0 7.5e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC71610.1 - 7.7e-06 25.4 0.0 0.00072 19.0 0.0 2.1 1 1 1 2 2 2 2 Kinase-like DUF4438 PF14505.6 PSC71610.1 - 0.021 13.8 0.2 0.032 13.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4438) Kdo PF06293.14 PSC71610.1 - 0.044 13.1 0.2 0.11 11.8 0.2 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PSC71610.1 - 0.045 13.7 0.0 0.045 13.7 0.0 1.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family RIO1 PF01163.22 PSC71610.1 - 0.051 13.2 0.0 0.078 12.6 0.0 1.2 1 0 0 1 1 1 0 RIO1 family ANAPC_CDC26 PF10471.9 PSC71610.1 - 4.8 8.1 12.2 11 6.9 12.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 Cupin_2 PF07883.11 PSC71611.1 - 4.7e-13 48.7 3.9 1.5e-11 43.9 0.6 2.5 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 PSC71611.1 - 2.3e-10 40.5 7.5 7.3e-10 38.9 0.1 3.3 4 0 0 4 4 4 2 AraC-like ligand binding domain Cupin_1 PF00190.22 PSC71611.1 - 5.7e-06 26.0 0.1 1.3e-05 24.9 0.1 1.5 1 0 0 1 1 1 1 Cupin Cupin_3 PF05899.12 PSC71611.1 - 0.00096 18.8 0.9 0.0019 17.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF861) ERM PF00769.19 PSC71612.1 - 0.18 11.6 19.1 0.01 15.6 14.1 1.4 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF966 PF06136.13 PSC71612.1 - 0.33 10.6 6.1 0.45 10.2 6.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) SGS PF05002.15 PSC71613.1 - 6.5e-25 87.1 5.3 1.2e-24 86.2 5.3 1.5 1 0 0 1 1 1 1 SGS domain CS PF04969.16 PSC71613.1 - 7e-13 49.4 0.0 1.1e-12 48.8 0.0 1.3 1 0 0 1 1 1 1 CS domain TPR_1 PF00515.28 PSC71613.1 - 1.5e-08 34.1 11.6 0.00086 19.0 0.7 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PSC71613.1 - 0.00013 21.8 16.7 0.00079 19.4 1.5 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PSC71613.1 - 0.00016 21.3 1.2 0.016 14.9 0.4 2.7 2 0 0 2 2 2 1 TPR repeat TPR_9 PF13371.6 PSC71613.1 - 0.0025 17.9 1.2 0.0025 17.9 1.2 3.0 2 1 1 3 3 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PSC71613.1 - 0.006 16.6 1.9 0.5 10.5 0.6 2.5 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 PSC71613.1 - 0.011 16.3 6.9 0.011 16.3 6.9 4.1 3 2 1 4 4 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 PSC71613.1 - 0.036 14.4 0.3 0.11 12.9 0.3 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat MIT PF04212.18 PSC71613.1 - 0.55 10.3 6.7 1.9 8.6 6.7 2.0 1 1 0 1 1 1 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 PSC71613.1 - 0.66 10.2 6.4 1.1 9.5 6.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 Alkyl_sulf_dimr PF14863.6 PSC71613.1 - 0.76 10.2 6.1 0.34 11.4 3.2 1.9 2 0 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_7 PF13176.6 PSC71613.1 - 1.7 8.9 4.8 5 7.4 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 PSC71613.1 - 2.4 8.6 9.0 4.6 7.7 0.2 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.6 PSC71613.1 - 6.4 7.9 25.8 0.47 11.4 0.5 4.1 2 1 2 4 4 3 0 Tetratricopeptide repeat GDP_Man_Dehyd PF16363.5 PSC71614.1 - 4.4e-62 210.4 0.0 5.1e-62 210.2 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PSC71614.1 - 2.8e-50 171.0 0.0 3.7e-50 170.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PSC71614.1 - 3.9e-16 58.9 0.0 1.2e-15 57.3 0.0 1.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 PSC71614.1 - 1.5e-14 53.8 0.0 7.6e-14 51.5 0.0 1.9 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 PSC71614.1 - 6.8e-09 35.2 0.0 1e-08 34.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 PSC71614.1 - 1.2e-07 31.4 0.0 3.6e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase NAD_binding_10 PF13460.6 PSC71614.1 - 1.4e-07 31.6 0.0 2.5e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 PSC71614.1 - 3.6e-07 29.6 0.0 7.4e-07 28.6 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein KR PF08659.10 PSC71614.1 - 9.3e-07 28.9 0.0 1.5e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.6 PSC71614.1 - 0.00012 21.8 0.0 0.0002 21.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase NmrA PF05368.13 PSC71614.1 - 0.0077 15.8 0.0 0.021 14.4 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family 3HCDH_N PF02737.18 PSC71614.1 - 0.022 14.7 0.1 0.069 13.0 0.0 1.9 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 PSC71614.1 - 0.025 14.8 0.0 0.051 13.8 0.0 1.5 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain ubiquitin PF00240.23 PSC71615.1 - 9.5e-97 316.8 9.1 4.1e-34 116.2 0.4 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 PSC71615.1 - 2.8e-49 164.8 12.0 3.6e-16 58.7 0.5 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PSC71615.1 - 1.1e-18 67.5 3.5 0.00022 21.6 0.1 4.4 3 3 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 PSC71615.1 - 3.2e-13 49.4 0.8 0.0034 17.3 0.0 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 PSC71615.1 - 1.6e-09 37.9 2.3 0.085 13.0 0.0 4.1 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 PSC71615.1 - 3e-09 37.1 2.5 0.03 14.7 0.1 3.1 1 1 2 3 3 3 3 Ubiquitin-like domain DUF2407 PF10302.9 PSC71615.1 - 4.1e-09 36.9 0.2 0.13 12.8 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 PSC71615.1 - 1.8e-05 24.7 15.5 7.4 6.7 0.2 5.9 6 0 0 6 6 6 3 Ubiquitin-like domain DUF3861 PF12977.7 PSC71615.1 - 0.00038 20.6 0.6 5.4 7.2 0.0 3.2 3 0 0 3 3 3 2 Domain of Unknown Function with PDB structure (DUF3861) Methyltrans_RNA PF04452.14 PSC71615.1 - 0.00051 19.5 0.5 0.48 9.7 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase Sde2_N_Ubi PF13019.6 PSC71615.1 - 0.00066 19.5 0.0 1.4 8.7 0.0 2.5 1 1 1 2 2 2 2 Silencing defective 2 N-terminal ubiquitin domain UN_NPL4 PF11543.8 PSC71615.1 - 0.00074 19.9 0.3 1.7 9.2 0.0 3.3 3 0 0 3 3 3 1 Nuclear pore localisation protein NPL4 Raf1_HTH PF18579.1 PSC71615.1 - 0.017 14.8 0.1 22 4.8 0.0 3.2 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain DUF2870 PF11069.8 PSC71615.1 - 0.018 15.4 0.1 33 4.9 0.0 3.5 3 2 0 3 3 3 0 Protein of unknown function (DUF2870) ACT_5 PF13710.6 PSC71615.1 - 0.049 13.5 1.6 9.6 6.1 0.0 2.7 3 0 0 3 3 3 0 ACT domain Big_7 PF17957.1 PSC71615.1 - 0.091 13.5 0.0 29 5.5 0.0 2.4 2 0 0 2 2 2 0 Bacterial Ig domain UDP-g_GGTase PF06427.11 PSC71615.1 - 0.095 12.8 1.2 2.9 8.1 0.0 2.9 3 0 0 3 3 3 0 UDP-glucose:Glycoprotein Glucosyltransferase ProRS-C_2 PF09181.10 PSC71615.1 - 0.1 12.7 1.8 37 4.5 0.1 3.1 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal Plexin_cytopl PF08337.12 PSC71615.1 - 0.18 10.5 4.9 11 4.6 0.3 3.4 2 1 0 3 3 3 0 Plexin cytoplasmic RasGAP domain Tash_PEST PF07708.11 PSC71615.1 - 0.4 10.9 9.6 4.5 7.6 1.4 2.5 2 0 0 2 2 2 0 Tash protein PEST motif Phage_sheath_1N PF17481.2 PSC71615.1 - 0.54 10.8 3.5 72 3.9 3.5 3.0 1 1 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain DHC_N1 PF08385.12 PSC71616.1 - 3.3e-117 392.5 0.0 4.3e-117 392.1 0.0 1.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 FolB PF02152.18 PSC71617.1 - 1.1e-31 109.6 0.1 1.2e-31 109.5 0.1 1.0 1 0 0 1 1 1 1 Dihydroneopterin aldolase CKS PF01111.19 PSC71618.1 - 2.1e-30 104.8 3.9 1.8e-29 101.8 3.9 1.9 1 1 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit IF-2B PF01008.17 PSC71619.1 - 2e-71 240.5 0.1 2.6e-71 240.1 0.1 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family APH PF01636.23 PSC71619.1 - 6.7e-20 72.0 2.1 6.7e-20 72.0 2.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family APH_6_hur PF04655.14 PSC71619.1 - 1.4e-05 24.6 0.0 5.4e-05 22.7 0.0 2.0 1 0 0 1 1 1 1 Aminoglycoside/hydroxyurea antibiotic resistance kinase Fructosamin_kin PF03881.14 PSC71619.1 - 0.0079 15.4 0.0 0.015 14.5 0.0 1.4 1 0 0 1 1 1 1 Fructosamine kinase Choline_kinase PF01633.20 PSC71619.1 - 0.04 13.5 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase EcKinase PF02958.20 PSC71619.1 - 0.088 12.1 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Ecdysteroid kinase Ribosomal_L19 PF01245.20 PSC71620.1 - 7.5e-31 106.3 0.1 1e-30 105.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L19 malic PF00390.19 PSC71621.1 - 6.5e-54 182.5 0.0 1e-53 181.9 0.0 1.3 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain Malic_M PF03949.15 PSC71621.1 - 6.3e-48 163.3 0.0 8.4e-48 162.9 0.0 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain Acetyltransf_2 PF00797.17 PSC71622.1 - 2.3e-45 155.2 1.5 1e-24 87.7 0.0 3.0 1 1 2 3 3 3 3 N-acetyltransferase Transglut_core PF01841.19 PSC71622.1 - 0.13 12.8 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Transglutaminase-like superfamily Erv26 PF04148.13 PSC71623.1 - 1.2e-33 116.7 1.3 5e-33 114.7 1.3 1.8 1 1 0 1 1 1 1 Transmembrane adaptor Erv26 DEAD PF00270.29 PSC71624.1 - 1.4e-43 148.7 0.0 3.2e-43 147.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC71624.1 - 5.8e-30 103.9 0.0 1.7e-29 102.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC71624.1 - 2.7e-05 24.2 0.0 0.00037 20.6 0.0 2.5 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit zf-CCHC PF00098.23 PSC71624.1 - 0.00038 20.4 2.2 0.00072 19.5 2.2 1.5 1 0 0 1 1 1 1 Zinc knuckle SecA_DEAD PF07517.14 PSC71624.1 - 0.025 13.9 1.7 0.11 11.8 1.7 1.9 1 1 0 1 1 1 0 SecA DEAD-like domain DNA_Packaging PF11053.8 PSC71624.1 - 0.057 13.3 0.3 0.26 11.1 0.1 2.1 2 0 0 2 2 2 0 Terminase DNA packaging enzyme UTP25 PF06862.12 PSC71624.1 - 0.12 11.1 0.0 0.35 9.6 0.0 1.7 2 0 0 2 2 2 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Methyltransf_25 PF13649.6 PSC71625.1 - 0.00069 20.3 0.0 0.64 10.8 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 PSC71625.1 - 0.0022 17.8 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC71625.1 - 0.01 15.6 0.0 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 PSC71625.1 - 0.048 14.3 0.2 3.1 8.5 0.2 2.4 1 1 0 1 1 1 0 Methyltransferase domain Cgr1 PF03879.14 PSC71626.1 - 4e-09 36.8 20.1 4e-09 36.8 20.1 2.0 2 0 0 2 2 2 1 Cgr1 family HNOBA PF07701.14 PSC71626.1 - 9.6 5.6 6.6 0.93 8.9 1.9 1.6 2 0 0 2 2 2 0 Heme NO binding associated RRM_1 PF00076.22 PSC71627.1 - 1.3e-30 105.0 0.8 3e-15 55.8 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PSC71627.1 - 4.2e-12 46.0 0.3 0.00017 21.6 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif TFIIA PF03153.13 PSC71627.1 - 3.8 7.4 28.9 8.1 6.3 28.9 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ABC1 PF03109.16 PSC71628.1 - 2e-26 92.5 0.1 3.8e-26 91.6 0.1 1.4 1 0 0 1 1 1 1 ABC1 family PABP PF00658.18 PSC71628.1 - 1.3e-24 86.2 0.2 2.8e-24 85.1 0.2 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RIO1 PF01163.22 PSC71628.1 - 0.038 13.6 0.0 0.07 12.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 PSC71628.1 - 0.24 10.9 0.0 0.45 10.1 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase CdiI_3 PF18616.1 PSC71628.1 - 0.52 10.2 2.0 22 5.0 0.1 2.9 3 0 0 3 3 3 0 CDI immunity proteins ABC1 PF03109.16 PSC71629.1 - 2.1e-26 92.4 0.1 3.8e-26 91.6 0.1 1.4 1 0 0 1 1 1 1 ABC1 family PABP PF00658.18 PSC71629.1 - 1.3e-24 86.2 0.2 2.8e-24 85.1 0.2 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RIO1 PF01163.22 PSC71629.1 - 0.038 13.6 0.0 0.071 12.7 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 PSC71629.1 - 0.1 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase CdiI_3 PF18616.1 PSC71629.1 - 0.52 10.2 2.0 22 5.0 0.1 2.9 3 0 0 3 3 3 0 CDI immunity proteins Ribosomal_L10 PF00466.20 PSC71630.1 - 1e-21 76.9 0.1 1.7e-21 76.2 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L10 P22_Cro PF14549.6 PSC71630.1 - 0.16 11.9 0.8 0.6 10.0 0.3 2.2 2 0 0 2 2 2 0 DNA-binding transcriptional regulator Cro Prefoldin PF02996.17 PSC71631.1 - 1.4e-22 79.8 0.4 2.7e-22 78.9 0.4 1.5 1 0 0 1 1 1 1 Prefoldin subunit RWP-RK PF02042.15 PSC71631.1 - 4.9e-16 58.4 0.0 1.2e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 RWP-RK domain HTH_17 PF12728.7 PSC71631.1 - 0.00089 19.4 0.0 0.0025 18.0 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain Prefoldin_2 PF01920.20 PSC71631.1 - 0.04 13.9 1.2 0.41 10.6 0.1 2.2 2 0 0 2 2 2 0 Prefoldin subunit Sulfotransfer_1 PF00685.27 PSC71632.1 - 8.6e-25 87.7 0.0 1.9e-24 86.6 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 PSC71632.1 - 2e-08 34.9 0.0 2e-05 25.1 0.0 2.3 1 1 1 2 2 2 2 Sulfotransferase family Amino_oxidase PF01593.24 PSC71633.1 - 1.8e-70 238.5 0.0 2.1e-70 238.3 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PSC71633.1 - 1.9e-14 53.6 0.1 4.6e-14 52.4 0.0 1.7 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 PSC71633.1 - 1.9e-05 23.7 0.0 0.0023 16.8 0.0 2.1 2 0 0 2 2 2 2 MCRA family Pyr_redox_2 PF07992.14 PSC71633.1 - 0.0002 20.7 0.1 0.0089 15.3 0.2 2.6 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PSC71633.1 - 0.00022 20.9 0.0 0.018 14.7 0.0 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 PSC71633.1 - 0.00077 20.0 0.2 0.11 13.0 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 PSC71633.1 - 0.0055 16.0 0.2 0.013 14.8 0.2 1.6 2 0 0 2 2 2 1 FAD binding domain FAD_binding_2 PF00890.24 PSC71633.1 - 0.0064 15.6 0.8 0.0099 15.0 0.8 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 PSC71633.1 - 0.0073 15.6 0.1 0.013 14.8 0.1 1.3 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 PSC71633.1 - 0.0082 15.5 0.0 0.014 14.8 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 PSC71633.1 - 0.076 11.8 0.1 4.9 5.9 0.0 2.2 2 0 0 2 2 2 0 Tryptophan halogenase HI0933_like PF03486.14 PSC71633.1 - 0.17 10.5 0.3 0.58 8.8 0.5 1.7 2 0 0 2 2 2 0 HI0933-like protein DUF3128 PF11326.8 PSC71634.1 - 7.9e-17 61.4 7.5 1.2e-16 60.9 7.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) CreA PF05981.12 PSC71635.1 - 1.2e-26 93.3 0.1 2e-26 92.5 0.1 1.3 1 0 0 1 1 1 1 CreA protein DUF4225 PF13988.6 PSC71635.1 - 0.16 11.6 0.1 0.29 10.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4225) Myb_DNA-binding PF00249.31 PSC71636.1 - 4.1e-31 106.9 7.6 4.1e-15 55.7 1.4 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC71636.1 - 1.4e-23 82.8 3.3 8.5e-18 64.4 1.0 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PSC71636.1 - 0.0014 18.5 2.5 0.033 14.1 0.0 2.9 2 1 1 3 3 3 1 Myb DNA-binding like Roughex PF06020.11 PSC71636.1 - 0.043 12.9 5.4 0.077 12.1 5.4 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Spt20 PF12090.8 PSC71636.1 - 0.11 12.1 16.6 0.17 11.5 16.6 1.2 1 0 0 1 1 1 0 Spt20 family MoaE PF02391.17 PSC71636.1 - 0.13 12.6 0.2 0.54 10.6 0.0 2.1 2 0 0 2 2 2 0 MoaE protein DUF5349 PF17298.2 PSC71636.1 - 3.2 7.4 8.0 5.7 6.6 8.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5349) Suf PF05843.14 PSC71636.1 - 3.6 7.5 8.3 5.4 6.9 8.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PBP1_TM PF14812.6 PSC71636.1 - 3.8 8.0 6.4 1.6 9.2 2.6 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2722 PF10846.8 PSC71636.1 - 7.2 5.4 19.6 0.0081 15.2 7.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) WD40 PF00400.32 PSC71637.1 - 2.5e-20 72.4 11.2 1.7e-06 28.6 0.4 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 PSC71637.1 - 7.2e-17 61.4 0.0 2.6e-16 59.6 0.0 2.0 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 PSC71637.1 - 0.00054 20.2 0.1 0.012 15.9 0.1 2.9 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Sgf11 PF08209.11 PSC71638.1 - 2e-17 62.4 1.0 2.8e-17 62.0 1.0 1.2 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) zf-C2HC_2 PF13913.6 PSC71638.1 - 7.7e-05 22.5 0.9 0.00016 21.5 0.9 1.5 1 0 0 1 1 1 1 zinc-finger of a C2HC-type PRMT5 PF05185.16 PSC71639.1 - 7.3e-66 221.3 0.0 1.1e-65 220.7 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_C PF17286.2 PSC71639.1 - 7.1e-54 182.4 0.1 1e-53 181.8 0.1 1.3 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Methyltransf_25 PF13649.6 PSC71639.1 - 3.9e-05 24.3 0.0 0.0001 22.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC71639.1 - 0.004 17.8 0.0 0.013 16.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 PSC71639.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein UPF0020 PF01170.18 PSC71639.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 LRR_8 PF13855.6 PSC71640.1 - 0.0026 17.5 0.1 0.047 13.4 0.0 2.3 1 1 1 2 2 2 2 Leucine rich repeat EF-hand_8 PF13833.6 PSC71641.1 - 1.5e-10 40.8 0.4 0.0027 17.5 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 PSC71641.1 - 3.6e-10 38.9 0.0 0.23 11.5 0.0 4.4 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 PSC71641.1 - 1.1e-09 37.1 0.6 0.024 14.2 0.0 3.6 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 PSC71641.1 - 2.8e-08 34.1 0.0 0.00044 20.7 0.0 2.6 1 1 1 2 2 2 2 EF-hand domain pair Acetyltransf_1 PF00583.25 PSC71641.1 - 0.00046 20.4 0.0 0.00087 19.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family EF-hand_5 PF13202.6 PSC71641.1 - 0.0056 16.1 0.8 13 5.4 0.0 3.4 3 0 0 3 3 3 1 EF hand Acetyltransf_10 PF13673.7 PSC71641.1 - 0.011 15.7 0.0 0.026 14.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SBP_bac_3 PF00497.20 PSC71642.1 - 1.4e-15 57.4 0.0 9.6e-14 51.3 0.0 2.2 1 1 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 PSC71642.1 - 0.0053 16.6 0.0 0.014 15.3 0.0 1.5 1 1 0 1 1 1 1 Ligand-gated ion channel Xan_ur_permease PF00860.20 PSC71643.1 - 3.3e-28 98.5 23.5 1.3e-15 57.0 6.7 2.6 2 1 0 2 2 2 2 Permease family FHA PF00498.26 PSC71643.1 - 8.7e-07 29.2 0.0 1.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 FHA domain Sulfate_transp PF00916.20 PSC71643.1 - 0.034 12.9 17.8 0.019 13.8 2.6 2.3 2 0 0 2 2 2 0 Sulfate permease family Wzy_C PF04932.15 PSC71643.1 - 0.62 9.7 4.7 3.5 7.3 1.8 2.7 2 0 0 2 2 2 0 O-Antigen ligase MFS_MOT1 PF16983.5 PSC71643.1 - 1.7 9.1 19.1 0.64 10.4 5.4 3.5 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily Cu2_monoox_C PF03712.15 PSC71645.1 - 3.1e-23 82.0 0.0 5.1e-23 81.3 0.0 1.3 1 0 0 1 1 1 1 Copper type II ascorbate-dependent monooxygenase, C-terminal domain Cu2_monooxygen PF01082.20 PSC71645.1 - 1.1e-16 61.2 0.1 5e-16 59.1 0.0 2.1 2 0 0 2 2 2 1 Copper type II ascorbate-dependent monooxygenase, N-terminal domain NHL PF01436.21 PSC71645.1 - 6.9e-06 25.8 2.6 0.00031 20.6 0.1 2.9 2 0 0 2 2 2 1 NHL repeat TFIIA PF03153.13 PSC71645.1 - 7 6.5 24.2 10 6.0 24.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LTV PF04180.14 PSC71646.1 - 3.6e-22 79.7 0.0 1.1e-08 35.3 2.0 3.9 2 2 0 2 2 2 2 Low temperature viability protein WW PF00397.26 PSC71646.1 - 0.0009 19.3 0.9 0.0017 18.4 0.9 1.5 1 0 0 1 1 1 1 WW domain LTV PF04180.14 PSC71647.1 - 3.2e-22 79.8 0.0 8.5e-09 35.6 1.7 3.9 2 2 0 2 2 2 2 Low temperature viability protein WW PF00397.26 PSC71647.1 - 0.12 12.5 1.0 0.23 11.6 1.0 1.5 1 0 0 1 1 1 0 WW domain 60KD_IMP PF02096.20 PSC71648.1 - 3.2e-30 105.2 0.4 4.2e-30 104.8 0.4 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein TipAS PF07739.13 PSC71648.1 - 0.0015 19.1 0.4 0.021 15.4 0.1 2.4 2 0 0 2 2 2 1 TipAS antibiotic-recognition domain Wzy_C_2 PF11846.8 PSC71648.1 - 0.11 12.4 1.9 3.3 7.6 0.1 2.5 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Vma12 PF11712.8 PSC71648.1 - 0.12 12.5 0.0 0.28 11.3 0.0 1.5 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4307 PF14155.6 PSC71649.1 - 3.6e-05 23.5 0.4 4.9e-05 23.1 0.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4307) Herpes_capsid PF06112.11 PSC71649.1 - 3.1 7.8 12.1 3.3 7.8 12.1 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PepSY_2 PF13670.6 PSC71649.1 - 8.4 6.5 6.6 1.6 8.8 1.6 2.1 2 1 0 2 2 2 0 Peptidase propeptide and YPEB domain Bcl-2_BAD PF10514.9 PSC71650.1 - 0.02 15.4 5.1 0.033 14.7 5.1 1.3 1 0 0 1 1 1 0 Pro-apoptotic Bcl-2 protein, BAD DUF4677 PF15726.5 PSC71650.1 - 0.055 13.6 0.2 0.081 13.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) CBFD_NFYB_HMF PF00808.23 PSC71651.1 - 1.3e-09 38.2 0.0 2.4e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PSC71651.1 - 1.6e-06 28.5 3.1 4.6e-06 27.0 0.0 2.4 3 0 0 3 3 3 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 PSC71651.1 - 0.013 15.5 0.0 0.023 14.7 0.0 1.4 1 0 0 1 1 1 0 Bromodomain associated DCX PF03607.17 PSC71651.1 - 0.11 12.6 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Doublecortin TFIIA PF03153.13 PSC71651.1 - 0.25 11.3 15.5 0.3 11.0 15.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Folliculin PF11704.8 PSC71651.1 - 0.89 9.4 6.4 1.3 8.9 0.3 2.1 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Presenilin PF01080.17 PSC71651.1 - 2.9 6.6 6.6 3.2 6.4 6.6 1.2 1 0 0 1 1 1 0 Presenilin Suf PF05843.14 PSC71651.1 - 3.2 7.6 7.8 3.9 7.4 7.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RRM_1 PF00076.22 PSC71652.1 - 2.1e-41 139.6 0.0 5e-14 51.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 PSC71652.1 - 1.1e-40 139.7 0.0 1.9e-27 96.3 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC71652.1 - 5e-40 137.4 0.0 1.2e-27 96.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase RRM_7 PF16367.5 PSC71652.1 - 9e-12 45.0 0.1 0.00024 21.2 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif Nup35_RRM_2 PF14605.6 PSC71652.1 - 1.7e-09 37.5 0.3 0.0026 17.7 0.0 3.4 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif APH PF01636.23 PSC71652.1 - 0.0037 17.2 0.0 0.011 15.6 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family PHM7_cyt PF14703.6 PSC71652.1 - 0.0066 16.7 0.2 4.1 7.6 0.1 3.6 4 1 0 4 4 4 1 Cytosolic domain of 10TM putative phosphate transporter Pkinase_fungal PF17667.1 PSC71652.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RRM_1 PF00076.22 PSC71653.1 - 2.1e-41 139.6 0.0 5e-14 51.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pkinase PF00069.25 PSC71653.1 - 1.1e-40 139.6 0.0 1.9e-27 96.3 0.0 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC71653.1 - 5e-40 137.4 0.0 1.2e-27 96.9 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase RRM_7 PF16367.5 PSC71653.1 - 9.5e-12 44.9 0.1 0.00024 21.1 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif Nup35_RRM_2 PF14605.6 PSC71653.1 - 1.7e-09 37.5 0.3 0.0026 17.7 0.0 3.4 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif APH PF01636.23 PSC71653.1 - 0.0037 17.2 0.0 0.011 15.6 0.0 1.9 1 0 0 1 1 1 1 Phosphotransferase enzyme family PHM7_cyt PF14703.6 PSC71653.1 - 0.0069 16.6 0.3 4.1 7.6 0.1 3.6 4 1 0 4 4 4 1 Cytosolic domain of 10TM putative phosphate transporter Pkinase_fungal PF17667.1 PSC71653.1 - 0.15 10.8 0.0 0.22 10.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Ribosomal_S13_N PF08069.12 PSC71654.1 - 1.3e-29 102.0 0.4 2.8e-29 101.0 0.4 1.6 1 0 0 1 1 1 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 PSC71654.1 - 1.8e-13 50.5 0.8 3e-13 49.8 0.8 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 HSP70 PF00012.20 PSC71655.1 - 2.4e-114 382.7 20.6 3.9e-97 325.9 0.0 3.7 3 1 0 3 3 2 2 Hsp70 protein MreB_Mbl PF06723.13 PSC71655.1 - 5.7e-16 58.3 0.8 7.1e-13 48.1 0.0 3.3 3 0 0 3 3 3 1 MreB/Mbl protein TFIIB PF00382.19 PSC71655.1 - 5.9e-08 32.7 1.4 2.4e-07 30.7 0.1 2.6 3 0 0 3 3 2 1 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 PSC71655.1 - 9.7e-05 21.8 0.4 0.00017 21.0 0.4 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding FGGY_C PF02782.16 PSC71655.1 - 0.0099 15.6 0.6 0.061 13.1 0.6 2.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain CobT PF06213.12 PSC71655.1 - 0.035 13.5 25.8 0.12 11.7 25.8 2.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF913 PF06025.12 PSC71655.1 - 0.055 12.4 4.6 0.083 11.8 4.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) HTH_8 PF02954.19 PSC71655.1 - 0.065 13.0 1.3 3.8 7.4 0.0 2.7 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family StbA PF06406.11 PSC71655.1 - 0.069 12.4 0.1 0.24 10.6 0.0 1.8 2 0 0 2 2 2 0 StbA protein FtsA PF14450.6 PSC71655.1 - 0.1 13.0 0.2 63 4.1 0.0 3.6 2 1 0 2 2 2 0 Cell division protein FtsA Rrn6 PF10214.9 PSC71655.1 - 0.12 10.9 11.9 0.14 10.6 11.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Myc_N PF01056.18 PSC71655.1 - 0.18 11.6 7.2 0.36 10.7 7.2 1.4 1 0 0 1 1 1 0 Myc amino-terminal region CPSF100_C PF13299.6 PSC71655.1 - 0.42 10.8 12.9 0.39 10.9 10.1 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal PA26 PF04636.13 PSC71655.1 - 0.84 8.5 7.9 1.2 8.0 7.9 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Serinc PF03348.15 PSC71655.1 - 0.98 8.3 5.7 1.5 7.7 5.7 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) SID-1_RNA_chan PF13965.6 PSC71655.1 - 1.4 7.2 2.2 2.1 6.7 2.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF4820 PF16091.5 PSC71655.1 - 1.6 8.0 13.0 3.8 6.8 13.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DDHD PF02862.17 PSC71655.1 - 2.3 8.3 10.6 4.5 7.4 10.6 1.5 1 0 0 1 1 1 0 DDHD domain DUF2151 PF10221.9 PSC71655.1 - 3 6.3 9.8 3.9 5.9 9.8 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator TCP PF03634.13 PSC71655.1 - 7.4 7.1 23.1 2.4 8.7 19.9 1.8 2 0 0 2 2 1 0 TCP family transcription factor SUV3_C PF12513.8 PSC71656.1 - 1.8e-13 50.2 0.2 4e-13 49.1 0.2 1.6 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal Suv3_C_1 PF18147.1 PSC71656.1 - 2.6e-12 46.4 0.0 7e-12 45.0 0.0 1.8 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 PSC71656.1 - 4.9e-10 39.7 0.0 9.9e-10 38.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Paramyx_P_V_C PF03210.13 PSC71656.1 - 0.15 11.8 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Paramyxovirus P/V phosphoprotein C-terminal Ribosomal_L37ae PF01780.19 PSC71657.1 - 3.4e-39 132.8 7.8 7.7e-39 131.7 7.8 1.6 1 0 0 1 1 1 1 Ribosomal L37ae protein family Pkinase_Tyr PF07714.17 PSC71657.1 - 3.1e-36 125.0 0.0 2.4e-18 66.4 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PSC71657.1 - 7.6e-33 114.0 0.0 3.1e-18 66.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 PSC71657.1 - 0.059 13.3 0.3 0.5 10.3 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PSC71657.1 - 0.28 9.9 0.0 0.41 9.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase PAT1 PF09770.9 PSC71658.1 - 0.44 8.8 27.3 0.6 8.3 27.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 PSC71658.1 - 1.1 9.1 38.6 1.7 8.6 38.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SOG2 PF10428.9 PSC71658.1 - 2.3 7.3 8.4 3.9 6.6 8.4 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein IER PF05760.12 PSC71658.1 - 2.5 8.3 13.0 4.8 7.4 13.0 1.4 1 0 0 1 1 1 0 Immediate early response protein (IER) EPL1 PF10513.9 PSC71658.1 - 3 8.2 4.9 4.8 7.5 4.9 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Presenilin PF01080.17 PSC71658.1 - 7.3 5.2 7.9 11 4.7 7.9 1.1 1 0 0 1 1 1 0 Presenilin Pkinase_Tyr PF07714.17 PSC71659.1 - 1.6e-18 67.0 0.0 9e-16 57.9 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase LRR_8 PF13855.6 PSC71659.1 - 2.7e-18 65.5 4.6 2.7e-06 27.1 0.4 4.7 3 1 0 4 4 4 4 Leucine rich repeat Pkinase PF00069.25 PSC71659.1 - 4.1e-17 62.4 0.0 9.1e-17 61.3 0.0 1.5 1 1 1 2 2 2 1 Protein kinase domain LRR_4 PF12799.7 PSC71659.1 - 3.9e-14 52.5 3.5 0.0062 16.9 0.1 5.5 3 1 5 8 8 8 6 Leucine Rich repeats (2 copies) Kdo PF06293.14 PSC71659.1 - 0.0003 20.2 0.1 0.00057 19.3 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_9 PF14580.6 PSC71659.1 - 0.0042 16.6 0.7 0.7 9.4 0.1 2.7 1 1 2 3 3 3 1 Leucine-rich repeat LRR_1 PF00560.33 PSC71659.1 - 0.028 14.9 3.6 57 4.8 0.2 5.1 5 1 0 5 5 5 0 Leucine Rich Repeat PAT1 PF09770.9 PSC71662.1 - 1 7.6 4.0 1.5 7.0 4.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 cwf21 PF08312.12 PSC71663.1 - 4.5e-11 42.7 9.3 4.5e-11 42.7 9.3 2.5 2 0 0 2 2 2 1 cwf21 domain DUF4776 PF16003.5 PSC71663.1 - 2.5 7.0 20.8 3.2 6.7 20.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) GAGA_bind PF06217.12 PSC71663.1 - 4.6 7.4 20.7 6.9 6.9 20.7 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family PIGA PF08288.12 PSC71664.1 - 4.7e-41 139.3 0.7 9e-41 138.4 0.7 1.5 1 0 0 1 1 1 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 PSC71664.1 - 7.2e-31 107.5 2.7 1.3e-30 106.7 2.7 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 PSC71664.1 - 1.2e-24 87.3 1.1 1.4e-22 80.5 0.5 2.5 2 1 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 PSC71664.1 - 2.1e-23 82.7 0.0 6.7e-23 81.1 0.0 1.7 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 PSC71664.1 - 4.1e-15 56.6 2.0 4.1e-15 56.6 2.0 2.7 2 1 0 2 2 2 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 PSC71664.1 - 2.5e-05 24.3 0.1 4.6e-05 23.5 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 PSC71664.1 - 8.6e-05 22.9 0.0 8.6e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 TT_ORF2 PF02957.15 PSC71664.1 - 0.021 15.7 0.5 0.036 15.0 0.5 1.3 1 0 0 1 1 1 0 TT viral ORF2 Glyco_transf_5 PF08323.11 PSC71664.1 - 0.046 13.4 0.1 0.099 12.3 0.1 1.6 1 1 0 1 1 1 0 Starch synthase catalytic domain Ribosomal_S13 PF00416.22 PSC71665.1 - 9e-55 184.5 1.4 1e-54 184.3 1.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 PP28 PF10252.9 PSC71665.1 - 0.054 14.0 1.8 0.082 13.4 0.9 1.7 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 HUN PF08729.10 PSC71666.1 - 2e-10 40.5 1.1 4.1e-10 39.5 1.1 1.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Ribosomal_L14 PF00238.19 PSC71667.1 - 1.1e-34 119.2 0.1 1.3e-34 118.9 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Phospholip_B PF04916.13 PSC71668.1 - 2.4e-136 455.4 0.0 1.3e-113 380.4 0.0 2.1 2 0 0 2 2 2 2 Phospholipase B Chloroa_b-bind PF00504.21 PSC71668.1 - 1.7e-46 158.7 0.0 3.8e-46 157.6 0.0 1.7 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Alpha-amylase PF00128.24 PSC71668.1 - 2.9e-10 40.2 0.0 1.5e-06 28.0 0.0 2.6 1 1 1 2 2 2 2 Alpha amylase, catalytic domain Alpha-amylase_C PF02806.18 PSC71668.1 - 8.2e-05 23.0 0.1 0.00025 21.4 0.1 1.9 1 0 0 1 1 1 1 Alpha amylase, C-terminal all-beta domain CBM_48 PF02922.18 PSC71668.1 - 0.00016 22.0 0.0 0.078 13.3 0.0 2.7 2 0 0 2 2 2 2 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Rad51 PF08423.11 PSC71669.1 - 2.4e-43 148.3 0.0 3e-43 147.9 0.0 1.1 1 0 0 1 1 1 1 Rad51 AAA_25 PF13481.6 PSC71669.1 - 8.6e-14 51.6 0.1 1.4e-13 50.9 0.1 1.3 1 0 0 1 1 1 1 AAA domain ATPase PF06745.13 PSC71669.1 - 1.1e-09 38.0 0.0 6.6e-08 32.2 0.0 2.3 2 1 0 2 2 2 1 KaiC RecA PF00154.21 PSC71669.1 - 4.2e-07 29.7 0.0 4.6e-05 23.0 0.0 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein DnaB_C PF03796.15 PSC71669.1 - 6.1e-05 22.5 0.0 0.0034 16.7 0.0 2.3 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.6 PSC71669.1 - 0.0025 18.1 0.1 0.029 14.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_24 PF13479.6 PSC71669.1 - 0.0046 16.7 0.0 0.0074 16.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 PSC71669.1 - 0.021 14.6 1.1 0.16 11.7 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein PhoH PF02562.16 PSC71669.1 - 0.023 14.2 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein NMT1_3 PF16868.5 PSC71669.1 - 0.16 11.4 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family PrmA PF06325.13 PSC71671.1 - 4.2e-15 55.9 0.0 5.9e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 PSC71671.1 - 3.9e-12 46.0 0.0 5.9e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.18 PSC71671.1 - 1.1e-10 41.5 0.2 5.4e-10 39.3 0.2 1.9 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.6 PSC71671.1 - 1.8e-10 41.4 0.0 3.3e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC71671.1 - 4.3e-09 36.3 0.0 5.3e-09 36.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 PSC71671.1 - 8.3e-09 35.3 0.0 1.1e-08 34.9 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 PSC71671.1 - 2.7e-06 27.1 0.0 3.7e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.12 PSC71671.1 - 1.3e-05 25.7 0.2 2.8e-05 24.7 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 PSC71671.1 - 0.00028 20.9 0.1 0.00036 20.5 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 PSC71671.1 - 0.00068 19.7 0.1 0.0011 19.0 0.1 1.6 1 1 0 1 1 1 1 Methyltransferase domain AviRa PF11599.8 PSC71671.1 - 0.0015 18.0 0.7 0.075 12.5 0.1 2.7 1 1 2 3 3 3 1 RRNA methyltransferase AviRa Ubie_methyltran PF01209.18 PSC71671.1 - 0.0019 17.6 0.0 0.0025 17.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 PSC71671.1 - 0.0079 16.0 0.0 0.01 15.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC71671.1 - 0.0098 16.6 0.0 0.023 15.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 PSC71671.1 - 0.012 15.3 0.0 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein CMAS PF02353.20 PSC71671.1 - 0.039 13.2 0.0 0.045 13.0 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase N6_Mtase PF02384.16 PSC71671.1 - 0.1 11.8 0.0 0.25 10.6 0.0 1.6 1 1 0 1 1 1 0 N-6 DNA Methylase DUF2949 PF11165.8 PSC71671.1 - 0.11 12.9 0.3 65 4.0 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2949) DOT1 PF08123.13 PSC71671.1 - 0.13 11.8 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Histone methylation protein DOT1 FmrO PF07091.11 PSC71671.1 - 0.5 9.9 2.3 0.68 9.4 0.2 1.9 1 1 1 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) G-patch PF01585.23 PSC71672.1 - 2.6e-12 46.4 0.1 6.1e-12 45.2 0.1 1.7 1 0 0 1 1 1 1 G-patch domain DUF2722 PF10846.8 PSC71672.1 - 0.0084 15.1 1.3 0.011 14.7 1.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 PSC71672.1 - 0.037 13.6 6.7 0.057 13.0 6.7 1.3 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 PSC71672.1 - 0.59 10.1 14.7 0.78 9.7 14.7 1.3 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ATP-synt_D PF01813.17 PSC71673.1 - 3.6e-72 242.3 1.0 4.8e-72 241.9 1.0 1.2 1 0 0 1 1 1 1 ATP synthase subunit D Hemerythrin PF01814.23 PSC71674.1 - 3.6e-29 102.0 40.5 8.4e-13 49.1 4.9 5.8 3 2 0 3 3 3 3 Hemerythrin HHE cation binding domain zinc_ribbon_6 PF14599.6 PSC71674.1 - 3.9e-21 74.8 0.1 3.9e-21 74.8 0.1 2.8 3 0 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.12 PSC71674.1 - 4.5e-18 65.5 21.2 4.5e-18 65.5 21.2 3.9 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 PSC71674.1 - 3e-08 33.8 6.6 3e-08 33.8 6.6 4.3 2 1 2 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.6 PSC71674.1 - 0.00037 20.3 7.9 0.00037 20.3 7.9 3.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC71674.1 - 0.002 18.0 7.7 0.002 18.0 7.7 4.8 4 2 1 5 5 5 1 zinc-RING finger domain Acid_PPase PF12689.7 PSC71675.1 - 3.9e-52 176.5 0.0 4.4e-52 176.3 0.0 1.0 1 0 0 1 1 1 1 Acid Phosphatase zf-MYND PF01753.18 PSC71676.1 - 9.2e-07 28.9 9.4 9.2e-07 28.9 9.4 1.9 2 0 0 2 2 2 1 MYND finger Brix PF04427.18 PSC71677.1 - 2.1e-40 138.9 0.0 2.8e-40 138.5 0.0 1.1 1 0 0 1 1 1 1 Brix domain Metallophos PF00149.28 PSC71678.1 - 2.1e-19 70.8 0.9 3.4e-19 70.1 0.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PSC71678.1 - 3.6e-05 24.0 0.0 0.00048 20.4 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ArfGap PF01412.18 PSC71679.1 - 8.7e-31 106.4 0.0 3.8e-30 104.4 0.0 2.1 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 PSC71679.1 - 1.6e-27 96.8 0.6 2.3e-27 96.2 0.6 1.3 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 PSC71679.1 - 1.2e-18 67.5 0.0 2e-18 66.8 0.0 1.4 1 0 0 1 1 1 1 PH domain Ank_2 PF12796.7 PSC71679.1 - 5.8e-08 33.2 0.0 1.3e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) BAR PF03114.18 PSC71679.1 - 1.1e-07 31.7 0.1 1.1e-07 31.7 0.1 1.5 2 0 0 2 2 2 1 BAR domain Ank PF00023.30 PSC71679.1 - 3.3e-07 30.5 0.2 0.012 16.0 0.1 3.0 2 0 0 2 2 2 2 Ankyrin repeat PH_8 PF15409.6 PSC71679.1 - 1.8e-05 24.9 0.0 4e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Ank_5 PF13857.6 PSC71679.1 - 1.9e-05 24.9 0.3 0.011 16.0 0.0 2.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC71679.1 - 2.7e-05 24.2 0.2 0.62 10.8 0.0 3.0 3 0 0 3 3 2 2 Ankyrin repeat PH_11 PF15413.6 PSC71679.1 - 0.0024 18.3 1.6 0.012 16.0 1.6 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain Ank_4 PF13637.6 PSC71679.1 - 0.015 15.8 0.0 0.036 14.7 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (many copies) CLZ PF16526.5 PSC71679.1 - 0.074 13.4 0.3 4.2 7.8 0.0 2.9 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels NIR_SIR PF01077.22 PSC71680.1 - 5.1e-50 169.1 0.0 1.2e-35 122.4 0.0 2.2 2 0 0 2 2 2 2 Nitrite and sulphite reductase 4Fe-4S domain NIR_SIR_ferr PF03460.17 PSC71680.1 - 1.5e-36 124.1 0.0 1.8e-17 63.0 0.0 2.6 2 0 0 2 2 2 2 Nitrite/Sulfite reductase ferredoxin-like half domain DUF202 PF02656.15 PSC71681.1 - 1.7e-12 47.6 4.6 6.3e-12 45.8 2.2 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF5391 PF17369.2 PSC71681.1 - 0.023 14.7 1.9 0.034 14.2 1.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5391) GDA1_CD39 PF01150.17 PSC71682.1 - 6.8e-59 199.6 0.0 2.7e-41 141.6 0.0 2.0 2 0 0 2 2 2 2 GDA1/CD39 (nucleoside phosphatase) family PGM_PMM_I PF02878.16 PSC71684.1 - 5.2e-24 84.5 0.0 1.3e-23 83.3 0.0 1.7 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 PSC71684.1 - 2.6e-21 76.2 0.2 1.3e-20 73.9 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 PSC71684.1 - 2.8e-12 46.9 0.0 5.5e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III Mem_trans PF03547.18 PSC71685.1 - 0.32 9.4 23.4 0.26 9.6 0.1 3.8 2 1 0 2 2 2 0 Membrane transport protein rve PF00665.26 PSC71686.1 - 8e-19 68.0 0.2 2.5e-18 66.4 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 PSC71686.1 - 0.0089 15.8 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain zf-DNL PF05180.12 PSC71687.1 - 1.6e-11 44.0 0.1 2.7e-11 43.2 0.1 1.3 1 0 0 1 1 1 1 DNL zinc finger RRM_1 PF00076.22 PSC71688.1 - 6.2e-13 48.4 0.0 1.1e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PSC71688.1 - 0.00035 20.5 0.0 0.00058 19.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 PSC71688.1 - 0.026 14.6 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif RRM_1 PF00076.22 PSC71689.1 - 6e-13 48.4 0.0 1.1e-12 47.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PSC71689.1 - 0.00035 20.5 0.0 0.00059 19.8 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 PSC71689.1 - 0.027 14.6 0.0 0.048 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif Voltage_CLC PF00654.20 PSC71690.1 - 4.7e-81 272.8 20.2 4.7e-81 272.8 20.2 2.0 2 0 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 PSC71690.1 - 2.4e-06 27.9 0.7 0.049 14.1 0.0 3.1 3 0 0 3 3 3 2 CBS domain CENP-Q PF13094.6 PSC71690.1 - 0.024 14.9 6.0 0.047 13.9 6.0 1.4 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DNA_pol_A_exo1 PF01612.20 PSC71691.1 - 8e-15 55.0 0.0 1.3e-14 54.3 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease zf-C2H2 PF00096.26 PSC71691.1 - 0.013 15.9 4.5 0.013 15.9 4.5 3.0 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-met PF12874.7 PSC71691.1 - 0.044 14.2 2.2 0.044 14.2 2.2 2.0 2 0 0 2 2 2 0 Zinc-finger of C2H2 type Methyltransf_13 PF08421.11 PSC71691.1 - 0.15 12.4 1.0 9.9 6.5 0.3 3.0 2 0 0 2 2 2 0 Putative zinc binding domain LRR_4 PF12799.7 PSC71692.1 - 2.1e-39 132.9 6.3 1.1e-08 35.2 0.0 7.8 6 2 1 8 8 8 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC71692.1 - 4.5e-27 93.6 32.6 4.6e-09 35.9 0.2 5.6 2 1 6 8 8 8 8 Leucine rich repeat LRR_9 PF14580.6 PSC71692.1 - 1.5e-22 79.9 0.3 2.9e-08 33.4 0.0 3.8 1 1 3 4 4 4 4 Leucine-rich repeat LRR_6 PF13516.6 PSC71692.1 - 3.8e-10 39.0 13.5 2.9 8.2 0.1 9.9 9 1 1 10 10 10 5 Leucine Rich repeat LRR_1 PF00560.33 PSC71692.1 - 4.2e-05 23.5 18.3 22 6.1 0.0 9.7 9 2 1 10 10 10 1 Leucine Rich Repeat TBCC PF07986.12 PSC71693.1 - 1.5e-33 115.1 0.1 1.9e-33 114.7 0.1 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor C Clathrin_lg_ch PF01086.17 PSC71693.1 - 3.8e-13 50.0 0.0 5.3e-13 49.5 0.0 1.2 1 0 0 1 1 1 1 Clathrin light chain Aa_trans PF01490.18 PSC71694.1 - 1e-34 120.0 6.5 4e-19 68.6 1.2 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein DUF4064 PF13273.6 PSC71694.1 - 0.0062 16.8 0.3 0.29 11.4 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF4064) CLASP_N PF12348.8 PSC71695.1 - 3.5e-35 121.6 0.0 2.3e-28 99.3 0.0 3.6 3 1 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 PSC71695.1 - 2.4e-05 24.2 25.5 0.0095 16.1 0.1 7.5 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 PSC71695.1 - 0.00043 20.6 1.0 0.00043 20.6 1.0 7.2 6 1 0 6 6 6 3 HEAT repeats HEAT_EZ PF13513.6 PSC71695.1 - 0.012 16.1 0.8 0.012 16.1 0.8 9.5 9 2 1 10 10 10 0 HEAT-like repeat MMS19_C PF12460.8 PSC71695.1 - 0.2 10.7 1.6 15 4.5 0.0 3.2 5 0 0 5 5 5 0 RNAPII transcription regulator C-terminal CLASP_N PF12348.8 PSC71696.1 - 3.5e-35 121.6 0.0 2.3e-28 99.3 0.0 3.6 3 1 0 3 3 3 2 CLASP N terminal HEAT PF02985.22 PSC71696.1 - 2.4e-05 24.2 25.5 0.0095 16.1 0.1 7.5 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 PSC71696.1 - 0.00043 20.6 1.0 0.00043 20.6 1.0 7.2 6 1 0 6 6 6 3 HEAT repeats HEAT_EZ PF13513.6 PSC71696.1 - 0.012 16.1 0.8 0.012 16.1 0.8 9.5 9 2 1 10 10 10 0 HEAT-like repeat MMS19_C PF12460.8 PSC71696.1 - 0.2 10.7 1.6 15 4.5 0.0 3.2 5 0 0 5 5 5 0 RNAPII transcription regulator C-terminal SapB_1 PF05184.15 PSC71700.1 - 1.1e-22 79.6 5.3 1.3e-07 31.5 0.2 3.6 3 0 0 3 3 3 3 Saposin-like type B, region 1 SapB_2 PF03489.17 PSC71700.1 - 1.2e-12 47.7 14.5 5.5e-08 32.8 0.6 5.3 6 0 0 6 6 6 3 Saposin-like type B, region 2 YtxH PF12732.7 PSC71700.1 - 0.069 13.7 0.0 13 6.4 0.0 2.6 2 0 0 2 2 2 0 YtxH-like protein Thioredoxin_3 PF13192.6 PSC71700.1 - 0.11 12.6 4.9 21 5.3 0.1 3.5 3 0 0 3 3 3 0 Thioredoxin domain DZR PF12773.7 PSC71700.1 - 0.21 11.7 6.4 1.5 8.9 0.2 3.6 3 1 0 3 3 3 0 Double zinc ribbon Aminotran_1_2 PF00155.21 PSC71701.1 - 1.6e-44 152.6 0.0 2.9e-44 151.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Pkinase_Tyr PF07714.17 PSC71701.1 - 1.6e-31 109.6 0.0 1.7e-30 106.2 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC71701.1 - 1.8e-24 86.5 0.0 4.7e-23 81.9 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Kinesin PF00225.23 PSC71702.1 - 2.2e-96 322.7 0.0 2.9e-96 322.3 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PSC71702.1 - 1.3e-42 145.2 0.0 2e-42 144.7 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding Peptidase_S8 PF00082.22 PSC71702.1 - 1e-37 130.0 5.2 1e-37 130.0 5.2 1.9 2 0 0 2 2 2 1 Subtilase family CENP-F_leu_zip PF10473.9 PSC71702.1 - 1.6e-05 25.0 6.9 1.6e-05 25.0 6.9 3.0 3 0 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 PSC71702.1 - 0.01 16.5 4.4 38 5.0 0.1 4.6 5 0 0 5 5 5 0 Initiation control protein YabA Macoilin PF09726.9 PSC71702.1 - 0.35 9.4 12.0 0.59 8.6 12.0 1.3 1 0 0 1 1 1 0 Macoilin family CC2-LZ PF16516.5 PSC71702.1 - 0.58 10.6 9.6 1.2 9.6 6.8 2.6 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator SPATA1_C PF15743.5 PSC71702.1 - 4.3 7.4 8.2 6.7 6.8 2.8 2.4 1 1 1 2 2 2 0 Spermatogenesis-associated C-terminus Kinesin PF00225.23 PSC71703.1 - 1.4e-96 323.3 0.0 1.8e-96 323.0 0.0 1.1 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PSC71703.1 - 1.6e-42 145.0 0.0 2.4e-42 144.4 0.0 1.3 1 0 0 1 1 1 1 Microtubule binding Peptidase_S8 PF00082.22 PSC71703.1 - 1e-37 130.0 5.2 1e-37 130.0 5.2 1.9 2 0 0 2 2 2 1 Subtilase family CENP-F_leu_zip PF10473.9 PSC71703.1 - 1.6e-05 25.0 6.9 1.6e-05 25.0 6.9 3.0 3 0 0 3 3 3 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 PSC71703.1 - 0.0096 16.5 4.3 38 5.0 0.1 4.6 5 0 0 5 5 5 0 Initiation control protein YabA Macoilin PF09726.9 PSC71703.1 - 0.29 9.7 11.7 0.48 8.9 11.7 1.3 1 0 0 1 1 1 0 Macoilin family CC2-LZ PF16516.5 PSC71703.1 - 0.58 10.6 9.6 1.2 9.6 6.8 2.6 1 1 1 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator SPATA1_C PF15743.5 PSC71703.1 - 4.3 7.4 8.2 6.7 6.8 2.8 2.4 1 1 1 2 2 2 0 Spermatogenesis-associated C-terminus Ecm29 PF13001.7 PSC71704.1 - 3.1e-110 369.2 0.0 6e-110 368.3 0.0 1.5 1 0 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.22 PSC71704.1 - 3.9e-07 29.8 27.3 0.87 10.0 0.0 11.4 11 0 0 11 11 11 3 HEAT repeat MMS19_C PF12460.8 PSC71704.1 - 0.0041 16.3 0.0 8.1 5.4 0.0 3.6 3 0 0 3 3 3 2 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 PSC71704.1 - 0.0079 16.8 0.0 1.5 9.4 0.0 3.6 3 1 1 4 4 4 2 Vacuolar 14 Fab1-binding region Arm PF00514.23 PSC71704.1 - 0.059 13.4 9.0 0.083 13.0 0.0 4.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 PSC71704.1 - 0.06 13.7 46.0 0.87 10.0 0.4 9.2 7 3 3 10 10 10 0 HEAT repeats HEAT_EZ PF13513.6 PSC71704.1 - 0.82 10.2 0.0 0.82 10.2 0.0 15.3 15 3 1 16 16 16 0 HEAT-like repeat UPF0561 PF10573.9 PSC71705.1 - 4e-05 23.7 1.5 4e-05 23.7 1.5 3.7 3 1 1 4 4 4 1 Uncharacterised protein family UPF0561 Spt5_N PF11942.8 PSC71705.1 - 0.0012 19.8 2.0 0.0012 19.8 2.0 5.9 7 0 0 7 7 7 1 Spt5 transcription elongation factor, acidic N-terminal Gln-synt_C PF00120.24 PSC71706.1 - 1.9e-85 286.9 0.0 6.1e-85 285.2 0.0 1.7 1 1 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 PSC71706.1 - 5e-10 39.2 0.0 9.6e-10 38.3 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain Gln-synt_N PF03951.19 PSC71706.1 - 0.0086 15.8 0.0 0.053 13.2 0.0 2.0 1 1 0 1 1 1 1 Glutamine synthetase, beta-Grasp domain SBP PF03110.14 PSC71707.1 - 4.2e-27 94.3 4.0 4.2e-27 94.3 4.0 2.3 2 0 0 2 2 2 1 SBP domain Glyco_hydro_32N PF00251.20 PSC71708.1 - 4.8e-57 193.9 0.0 8.6e-44 150.3 0.0 3.0 2 1 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 PSC71708.1 - 7.4e-10 39.0 0.0 1.3e-08 35.0 0.0 2.2 2 0 0 2 2 2 1 Glycosyl hydrolases family 32 C terminal Adaptin_binding PF10199.9 PSC71708.1 - 0.16 12.5 7.0 0.25 11.9 3.4 2.3 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 ORC_WH_C PF18137.1 PSC71708.1 - 6.1 6.9 8.1 3.7 7.6 2.1 2.4 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal SBP PF03110.14 PSC71709.1 - 2.9e-26 91.6 7.0 4.9e-26 90.9 7.0 1.4 1 0 0 1 1 1 1 SBP domain Ion_trans PF00520.31 PSC71711.1 - 1.3e-169 561.7 79.8 2.1e-43 148.3 8.4 5.1 4 1 1 5 5 5 5 Ion transport protein RRM_1 PF00076.22 PSC71711.1 - 1.7e-33 114.3 0.0 1.8e-13 50.1 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PKD_channel PF08016.12 PSC71711.1 - 2.4e-09 36.4 47.8 1.9e-06 26.9 3.1 6.3 5 2 2 7 7 7 4 Polycystin cation channel RRM_5 PF13893.6 PSC71711.1 - 1.9e-06 27.5 0.0 0.58 9.7 0.0 3.5 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GPHH PF16905.5 PSC71711.1 - 3.2e-06 26.8 0.0 9.5e-06 25.3 0.0 1.9 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Ion_trans PF00520.31 PSC71712.1 - 1.4e-169 561.5 80.1 2.1e-43 148.3 8.4 5.1 4 1 1 5 5 5 5 Ion transport protein RRM_1 PF00076.22 PSC71712.1 - 1.7e-33 114.3 0.0 1.8e-13 50.1 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PKD_channel PF08016.12 PSC71712.1 - 1.9e-09 36.7 47.4 1.9e-06 26.9 3.1 6.3 5 2 2 7 7 7 4 Polycystin cation channel RRM_5 PF13893.6 PSC71712.1 - 1.9e-06 27.5 0.0 0.58 9.8 0.0 3.5 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GPHH PF16905.5 PSC71712.1 - 3.2e-06 26.8 0.0 9.5e-06 25.3 0.0 1.9 1 0 0 1 1 1 1 Voltage-dependent L-type calcium channel, IQ-associated Ysc84 PF04366.12 PSC71713.1 - 6.2e-10 38.9 0.0 8e-09 35.3 0.0 2.5 3 0 0 3 3 3 1 Las17-binding protein actin regulator NAR2 PF16974.5 PSC71714.1 - 7.5e-19 67.8 0.0 9.6e-19 67.4 0.0 1.1 1 0 0 1 1 1 1 High-affinity nitrate transporter accessory GPI-anchored PF10342.9 PSC71714.1 - 0.00068 20.3 0.7 0.0074 17.0 0.0 2.4 3 0 0 3 3 3 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family He_PIG PF05345.12 PSC71714.1 - 0.038 14.2 0.3 0.038 14.2 0.3 2.0 2 0 0 2 2 2 0 Putative Ig domain Aldedh PF00171.22 PSC71715.1 - 1.5e-43 149.0 0.0 1.9e-43 148.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family COX6B PF02297.17 PSC71716.1 - 4.9e-11 42.7 1.0 1.1e-10 41.6 1.0 1.5 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.13 PSC71716.1 - 0.0079 16.3 0.1 0.017 15.2 0.1 1.6 1 0 0 1 1 1 1 CHCH domain Ser_hydrolase PF06821.13 PSC71716.1 - 0.36 10.7 4.0 0.33 10.8 1.0 2.0 2 0 0 2 2 2 0 Serine hydrolase PQ-loop PF04193.14 PSC71717.1 - 6.8e-34 115.5 8.6 1e-18 66.9 3.8 2.4 2 0 0 2 2 2 2 PQ loop repeat Thioredoxin PF00085.20 PSC71718.1 - 8.9e-06 25.6 0.0 1.2e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 PSC71718.1 - 0.00067 19.6 0.0 0.0017 18.3 0.0 1.7 1 1 0 1 1 1 1 AhpC/TSA family OST3_OST6 PF04756.13 PSC71718.1 - 0.0011 18.4 0.0 0.0012 18.3 0.0 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 PSC71718.1 - 0.0017 18.8 0.0 0.0031 17.9 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain DUF2847 PF11009.8 PSC71718.1 - 0.044 13.7 0.0 0.086 12.8 0.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2847) Med9 PF07544.13 PSC71718.1 - 0.079 13.1 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 Thioredoxin_8 PF13905.6 PSC71718.1 - 0.13 12.6 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like RAI1 PF08652.11 PSC71719.1 - 3.5e-12 46.3 0.0 6.3e-12 45.5 0.0 1.4 1 0 0 1 1 1 1 RAI1 like PD-(D/E)XK nuclease YabA PF06156.13 PSC71719.1 - 0.36 11.5 5.3 1.9 9.2 2.6 2.5 2 0 0 2 2 2 0 Initiation control protein YabA BST2 PF16716.5 PSC71719.1 - 0.39 11.3 15.0 4.6 7.9 0.5 2.6 2 0 0 2 2 2 0 Bone marrow stromal antigen 2 BLOC1_2 PF10046.9 PSC71719.1 - 0.42 11.0 1.5 0.88 9.9 1.5 1.5 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 bZIP_1 PF00170.21 PSC71719.1 - 1.6 8.9 12.9 4.9 7.3 3.4 3.3 3 0 0 3 3 3 0 bZIP transcription factor GAS PF13851.6 PSC71719.1 - 3.3 7.0 8.0 0.52 9.6 3.6 1.7 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding CREPT PF16566.5 PSC71719.1 - 3.6 7.8 6.5 5.1 7.3 3.3 2.3 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour ATG16 PF08614.11 PSC71719.1 - 5.3 7.2 21.0 0.46 10.7 9.9 3.0 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) ZapB PF06005.12 PSC71719.1 - 7.9 7.0 18.0 0.092 13.2 3.5 3.0 3 1 0 3 3 3 0 Cell division protein ZapB UPF0242 PF06785.11 PSC71719.1 - 9.1 6.3 7.2 0.39 10.8 1.1 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus MFS_1 PF07690.16 PSC71720.1 - 3.6e-36 124.8 102.9 3.9e-19 68.8 38.1 3.9 2 2 2 4 4 4 3 Major Facilitator Superfamily DUF2534 PF10749.9 PSC71720.1 - 0.018 15.2 2.3 0.84 9.8 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2534) BolA PF01722.18 PSC71721.1 - 5.2e-16 58.7 0.1 6e-16 58.5 0.1 1.1 1 0 0 1 1 1 1 BolA-like protein 3HCDH PF00725.22 PSC71721.1 - 0.039 14.5 0.0 0.048 14.3 0.0 1.2 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain Aldo_ket_red PF00248.21 PSC71722.1 - 7.2e-50 169.8 0.0 2.8e-48 164.6 0.0 2.1 1 1 0 1 1 1 1 Aldo/keto reductase family CRM1_C PF08767.11 PSC71723.1 - 5.7e-114 380.6 4.8 1.1e-113 379.6 1.8 2.6 2 0 0 2 2 2 1 CRM1 C terminal Xpo1 PF08389.12 PSC71723.1 - 5e-39 133.7 4.9 2.1e-38 131.7 1.4 3.4 3 0 0 3 3 3 1 Exportin 1-like protein Exostosin PF03016.15 PSC71723.1 - 1.2e-33 116.7 0.0 2.1e-33 115.9 0.0 1.4 1 0 0 1 1 1 1 Exostosin family CRM1_repeat_2 PF18784.1 PSC71723.1 - 2.1e-31 107.4 2.5 5.2e-31 106.1 2.3 1.8 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 PSC71723.1 - 2.2e-24 85.3 0.1 6.2e-24 83.9 0.1 1.8 1 0 0 1 1 1 1 CRM1 / Exportin repeat 3 RWP-RK PF02042.15 PSC71723.1 - 2e-20 72.5 0.2 4.9e-20 71.3 0.2 1.7 1 0 0 1 1 1 1 RWP-RK domain CRM1_repeat PF18777.1 PSC71723.1 - 4.1e-17 61.4 0.3 8.8e-17 60.3 0.3 1.6 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 PSC71723.1 - 2.5e-11 43.3 0.0 6.5e-11 42.0 0.0 1.8 1 0 0 1 1 1 1 Importin-beta N-terminal domain HTH_28 PF13518.6 PSC71723.1 - 0.072 13.2 0.0 0.23 11.6 0.0 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain DUF3385 PF11865.8 PSC71723.1 - 0.089 12.7 1.1 1.8 8.5 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3385) Aldo_ket_red PF00248.21 PSC71724.1 - 1.8e-34 119.3 0.0 2.2e-34 119.0 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family SNF2_N PF00176.23 PSC71725.1 - 1.3e-63 214.9 0.0 1.9e-63 214.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-CW PF07496.15 PSC71725.1 - 4.2e-10 39.5 8.0 1.2e-09 38.0 8.0 1.8 1 0 0 1 1 1 1 CW-type Zinc Finger Helicase_C PF00271.31 PSC71725.1 - 3.7e-07 30.5 0.0 7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain F-box-like PF12937.7 PSC71725.1 - 0.00031 20.6 0.1 0.00071 19.4 0.1 1.6 1 0 0 1 1 1 1 F-box-like zf-C3HC4_3 PF13920.6 PSC71725.1 - 0.00064 19.5 6.1 0.0016 18.2 6.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) F-box PF00646.33 PSC71725.1 - 0.0051 16.7 0.0 0.011 15.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain Prok-RING_4 PF14447.6 PSC71725.1 - 0.047 13.6 7.8 0.11 12.4 7.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PSC71725.1 - 0.088 12.7 9.5 0.23 11.3 9.5 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC71725.1 - 0.4 10.7 8.4 1 9.4 8.4 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4 PF00097.25 PSC71725.1 - 0.94 9.4 13.2 0.15 12.0 8.8 2.0 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Metallophos PF00149.28 PSC71726.1 - 3e-07 31.2 0.0 0.00021 21.9 0.1 2.1 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Metallophos PF00149.28 PSC71727.1 - 4.1e-07 30.7 0.7 4.8e-06 27.2 0.7 2.1 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase ADP_ribosyl_GH PF03747.14 PSC71728.1 - 1.9e-31 109.9 5.0 2.7e-31 109.4 5.0 1.2 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase tRNA-synt_1g PF09334.11 PSC71729.1 - 5.7e-154 512.6 0.0 7.1e-154 512.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.20 PSC71729.1 - 7.4e-29 99.7 0.0 1.3e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain Anticodon_1 PF08264.13 PSC71729.1 - 5.7e-06 26.4 0.0 1.1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1 PF00133.22 PSC71729.1 - 1e-05 24.1 0.6 0.0018 16.6 0.0 2.7 2 1 0 3 3 3 2 tRNA synthetases class I (I, L, M and V) GST_C_2 PF13410.6 PSC71729.1 - 1.4e-05 25.0 0.5 1.4e-05 25.0 0.5 3.0 4 0 0 4 4 4 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PSC71729.1 - 0.0014 18.8 0.1 0.0044 17.2 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PSC71729.1 - 0.0052 16.9 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain tRNA-synt_1e PF01406.19 PSC71729.1 - 0.089 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain Cyt-b5 PF00173.28 PSC71730.1 - 3.1e-08 33.6 0.2 5.6e-08 32.8 0.2 1.5 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Sugar-bind PF04198.13 PSC71730.1 - 0.021 13.9 0.0 0.037 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative sugar-binding domain Cyt-b5 PF00173.28 PSC71731.1 - 3.8e-08 33.4 0.2 6.5e-08 32.6 0.2 1.4 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Sugar-bind PF04198.13 PSC71731.1 - 0.029 13.5 0.0 0.042 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative sugar-binding domain GCS2 PF04107.13 PSC71732.1 - 1.3e-86 290.5 0.0 2.3e-86 289.7 0.0 1.4 1 0 0 1 1 1 1 Glutamate-cysteine ligase family 2(GCS2) DEAD PF00270.29 PSC71732.1 - 3.6e-47 160.4 0.0 6.2e-47 159.6 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC71732.1 - 3.1e-30 104.8 0.0 8.4e-30 103.4 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain GUCT PF08152.12 PSC71732.1 - 1.4e-14 54.1 0.0 3.4e-14 52.9 0.0 1.7 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.15 PSC71732.1 - 0.00047 20.2 0.0 0.00081 19.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 PSC71732.1 - 0.0023 17.3 0.0 0.0043 16.4 0.0 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ERCC3_RAD25_C PF16203.5 PSC71732.1 - 0.014 14.6 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase S10_plectin PF03501.15 PSC71733.1 - 1.2e-43 147.0 0.1 1.5e-43 146.8 0.1 1.0 1 0 0 1 1 1 1 Plectin/S10 domain Mon1 PF03164.14 PSC71734.1 - 8.4e-79 265.5 0.0 1e-78 265.2 0.0 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 DUF4503 PF14951.6 PSC71734.1 - 0.067 11.6 0.0 0.1 11.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4503) Robl_LC7 PF03259.17 PSC71734.1 - 1.8 8.4 4.6 12 5.8 0.0 3.0 2 0 0 2 2 2 0 Roadblock/LC7 domain TRPM_tetra PF16519.5 PSC71735.1 - 0.0083 16.2 0.0 0.02 15.0 0.0 1.6 1 0 0 1 1 1 1 Tetramerisation domain of TRPM GCN5L1 PF06320.13 PSC71735.1 - 0.24 11.6 0.1 0.48 10.6 0.1 1.4 1 0 0 1 1 1 0 GCN5-like protein 1 (GCN5L1) TNFR_16_TM PF18422.1 PSC71735.1 - 0.46 10.5 2.5 3.1 7.8 2.5 2.1 1 1 0 1 1 1 0 Tumor necrosis factor receptor member 16 trans-membrane domain Laminin_II PF06009.12 PSC71735.1 - 0.46 10.5 1.4 13 5.8 0.2 2.2 1 1 1 2 2 2 0 Laminin Domain II SIMPL PF04402.14 PSC71736.1 - 6.3e-42 144.3 8.2 7.2e-42 144.1 8.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF541) VTC PF09359.10 PSC71737.1 - 2.6e-69 233.7 0.0 3.5e-69 233.3 0.0 1.2 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 PSC71737.1 - 6.3e-19 69.2 11.2 7.7e-09 35.9 0.9 3.5 3 1 1 4 4 4 3 SPX domain DUF202 PF02656.15 PSC71737.1 - 1.8e-11 44.3 0.6 1.8e-11 44.3 0.6 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) CCDC154 PF15450.6 PSC71737.1 - 0.057 12.0 1.1 0.059 11.9 0.1 1.4 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 154 Yip1 PF04893.17 PSC71737.1 - 0.24 11.1 3.8 0.43 10.3 3.8 1.3 1 0 0 1 1 1 0 Yip1 domain 2-Hacid_dh_C PF02826.19 PSC71738.1 - 3.3e-41 140.6 0.0 6e-41 139.8 0.0 1.4 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 PSC71738.1 - 1.1e-08 35.4 0.0 1.9e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh PF00389.30 PSC71738.1 - 0.0042 16.8 0.0 0.017 14.8 0.0 1.9 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ApbA PF02558.16 PSC71738.1 - 0.04 13.5 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA F420_oxidored PF03807.17 PSC71738.1 - 0.059 14.0 0.0 0.15 12.7 0.0 1.8 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent AbfB PF05270.13 PSC71738.1 - 0.076 13.0 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha-L-arabinofuranosidase B (ABFB) domain 3HCDH_N PF02737.18 PSC71738.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pkinase PF00069.25 PSC71739.1 - 1.3e-57 195.2 0.0 1.8e-57 194.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC71739.1 - 2.9e-30 105.4 0.0 4.3e-30 104.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC71739.1 - 0.00011 21.6 0.0 0.00022 20.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PSC71739.1 - 0.025 13.5 0.0 0.042 12.8 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain TolA_bind_tri PF16331.5 PSC71739.1 - 0.57 10.3 9.3 0.16 12.1 4.6 2.5 2 0 0 2 2 2 0 TolA binding protein trimerisation Nsp1_C PF05064.13 PSC71739.1 - 0.95 9.3 3.1 0.77 9.6 0.7 2.0 2 0 0 2 2 2 0 Nsp1-like C-terminal region MCC-bdg_PDZ PF10506.9 PSC71739.1 - 1 9.4 5.3 0.66 10.0 1.8 2.5 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome Spc24 PF08286.11 PSC71739.1 - 1.8 8.8 3.2 5 7.4 0.8 2.7 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 EamA PF00892.20 PSC71740.1 - 3.4e-05 24.0 23.9 0.017 15.3 7.4 3.3 3 0 0 3 3 3 2 EamA-like transporter family Ank_2 PF12796.7 PSC71741.1 - 1.3e-10 41.7 0.2 3.7e-05 24.2 0.0 3.6 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC71741.1 - 6.9e-08 32.6 0.3 2e-05 24.8 0.1 3.7 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.30 PSC71741.1 - 8.6e-08 32.3 5.7 0.00039 20.8 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 PSC71741.1 - 4.8e-06 27.0 3.5 1.5e-05 25.5 0.0 3.5 4 1 1 5 5 5 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC71741.1 - 0.0003 21.0 3.3 0.15 12.7 0.0 5.1 5 1 0 5 5 5 1 Ankyrin repeat Peptidase_C1 PF00112.23 PSC71743.1 - 1.2e-38 133.4 0.0 2e-38 132.6 0.0 1.4 1 0 0 1 1 1 1 Papain family cysteine protease FKBP_C PF00254.28 PSC71743.1 - 1.9e-11 44.1 0.0 3.5e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Inhibitor_I29 PF08246.12 PSC71743.1 - 0.0023 18.3 0.0 0.0038 17.6 0.0 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) AAA_12 PF13087.6 PSC71744.1 - 1.4e-51 175.0 0.0 3.8e-51 173.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 PSC71744.1 - 4.5e-50 170.9 3.0 4.5e-50 170.9 3.0 1.5 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PSC71744.1 - 2.3e-10 41.0 2.4 1.7e-09 38.1 2.4 2.3 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 PSC71744.1 - 0.0001 22.0 0.4 0.001 18.9 0.0 2.8 3 0 0 3 3 3 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 PSC71744.1 - 0.0004 20.2 0.2 2.5 7.8 0.0 3.6 4 0 0 4 4 4 1 Viral (Superfamily 1) RNA helicase UvrD-helicase PF00580.21 PSC71744.1 - 0.001 18.6 2.8 0.0024 17.4 2.7 1.6 1 1 1 2 2 2 1 UvrD/REP helicase N-terminal domain AAA_22 PF13401.6 PSC71744.1 - 0.0045 17.3 0.5 0.039 14.2 0.0 2.8 3 1 0 3 3 3 1 AAA domain DEAD PF00270.29 PSC71744.1 - 0.0053 16.5 0.3 0.1 12.4 0.3 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 PSC71744.1 - 0.077 13.0 0.0 0.19 11.7 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PPV_E1_N PF00524.18 PSC71744.1 - 0.13 12.7 0.3 12 6.4 0.0 2.3 2 0 0 2 2 2 0 E1 Protein, N terminal domain TFIIA PF03153.13 PSC71744.1 - 0.61 10.0 11.1 1 9.2 11.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PriC PF07445.12 PSC71744.1 - 1.6 8.6 11.5 3.2 7.6 11.5 1.4 1 0 0 1 1 1 0 Primosomal replication protein priC PsaN PF05479.11 PSC71745.1 - 1.5e-35 122.2 5.2 2e-35 121.9 5.2 1.1 1 0 0 1 1 1 1 Photosystem I reaction centre subunit N (PSAN or PSI-N) DUF3357 PF11837.8 PSC71745.1 - 0.35 11.4 3.6 1.2 9.6 3.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) RskA PF10099.9 PSC71745.1 - 0.38 11.0 8.7 0.47 10.7 8.7 1.1 1 0 0 1 1 1 0 Anti-sigma-K factor rskA CTP_transf_1 PF01148.20 PSC71747.1 - 0.0034 17.2 1.8 0.0034 17.2 1.8 2.0 2 0 0 2 2 2 1 Cytidylyltransferase family SET PF00856.28 PSC71748.1 - 0.12 12.8 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 SET domain Pkinase PF00069.25 PSC71749.1 - 2.7e-66 223.7 0.0 3.4e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC71749.1 - 6.6e-32 110.8 0.0 9.2e-32 110.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PSC71749.1 - 0.00012 21.5 0.1 0.0002 20.8 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PSC71749.1 - 0.00013 21.4 0.0 0.063 12.6 0.0 2.3 1 1 1 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 PSC71749.1 - 0.002 17.1 0.1 0.0037 16.3 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain FTA2 PF13095.6 PSC71749.1 - 0.1 12.2 0.2 0.24 11.0 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Exo_endo_phos PF03372.23 PSC71750.1 - 0.00052 19.6 0.9 0.0011 18.5 0.7 1.6 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Totivirus_coat PF05518.11 PSC71750.1 - 0.36 8.8 7.3 0.65 8.0 7.3 1.4 1 0 0 1 1 1 0 Totivirus coat protein HSP70 PF00012.20 PSC71751.1 - 0.0014 16.9 0.0 0.0018 16.5 0.0 1.0 1 0 0 1 1 1 1 Hsp70 protein DUF5308 PF17233.2 PSC71752.1 - 0.0045 17.2 0.4 0.0065 16.7 0.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5308) GATA-N PF05349.12 PSC71752.1 - 0.0073 16.6 0.4 0.011 16.1 0.4 1.4 1 0 0 1 1 1 1 GATA-type transcription activator, N-terminal ECSIT PF06239.11 PSC71752.1 - 0.26 10.4 2.6 0.37 9.9 2.6 1.1 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway PHD PF00628.29 PSC71754.1 - 1.8e-06 27.7 6.9 4e-06 26.6 6.9 1.6 1 0 0 1 1 1 1 PHD-finger DDHD PF02862.17 PSC71754.1 - 0.17 12.0 6.7 0.71 10.0 2.6 2.3 2 0 0 2 2 2 0 DDHD domain Rtf2 PF04641.12 PSC71754.1 - 0.3 10.4 10.2 6 6.1 0.1 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger Neur_chan_memb PF02932.16 PSC71754.1 - 6.1 6.8 10.4 44 4.0 7.2 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region 2-Hacid_dh_C PF02826.19 PSC71755.1 - 1.5e-51 174.3 0.0 2e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PSC71755.1 - 3.5e-32 110.9 0.0 4.1e-32 110.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 PSC71755.1 - 0.004 17.3 0.0 0.026 14.7 0.0 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase RNase_P_p30 PF01876.16 PSC71756.1 - 1.5e-51 175.0 0.0 2.2e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 RNase P subunit p30 PAS PF00989.25 PSC71757.1 - 6.6e-18 64.8 0.1 1.9e-08 34.3 0.0 4.7 4 0 0 4 4 4 4 PAS fold PAS_9 PF13426.7 PSC71757.1 - 5.8e-16 58.6 0.0 2.7e-07 30.8 0.0 4.2 4 0 0 4 4 4 3 PAS domain PAS_8 PF13188.7 PSC71757.1 - 1.8e-07 31.0 0.1 0.011 15.7 0.0 3.6 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 PSC71757.1 - 2.1e-05 24.8 0.1 0.3 11.4 0.0 4.2 4 0 0 4 4 4 2 PAS fold PAS_3 PF08447.12 PSC71757.1 - 0.00045 20.5 0.0 5.6 7.3 0.0 4.2 4 0 0 4 4 4 1 PAS fold T2SSM PF04612.12 PSC71757.1 - 0.012 15.7 5.3 0.071 13.2 5.3 2.4 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M PHD PF00628.29 PSC71758.1 - 3.7e-09 36.3 8.2 3.7e-09 36.3 8.2 4.4 4 1 0 4 4 4 1 PHD-finger PHD_2 PF13831.6 PSC71758.1 - 0.00068 19.1 2.7 0.00068 19.1 2.7 3.9 3 0 0 3 3 3 1 PHD-finger Agenet PF05641.12 PSC71758.1 - 0.0039 17.6 5.5 9.7 6.8 0.1 5.0 5 0 0 5 5 5 1 Agenet domain LBR_tudor PF09465.10 PSC71758.1 - 0.012 15.4 3.9 0.17 11.7 0.3 3.1 4 0 0 4 4 4 0 Lamin-B receptor of TUDOR domain TUDOR_5 PF18359.1 PSC71758.1 - 0.062 13.0 0.6 7.4 6.4 0.0 3.3 3 0 0 3 3 3 0 Histone methyltransferase Tudor domain 1 DUF4537 PF15057.6 PSC71758.1 - 0.16 12.0 0.5 5.1 7.1 0.1 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4537) COQ7 PF03232.13 PSC71759.1 - 1.5e-18 67.2 0.1 2.4e-18 66.5 0.1 1.4 1 1 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 PAD_porph PF04371.15 PSC71760.1 - 4.2e-96 322.0 0.0 6.2e-96 321.4 0.0 1.3 1 0 0 1 1 1 1 Porphyromonas-type peptidyl-arginine deiminase EMP24_GP25L PF01105.24 PSC71761.1 - 4e-44 150.7 0.2 4.5e-44 150.6 0.2 1.0 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD PAP_PilO PF06864.12 PSC71761.1 - 0.00035 19.5 0.4 0.0005 19.0 0.4 1.1 1 0 0 1 1 1 1 Pilin accessory protein (PilO) SdrD_B PF17210.3 PSC71761.1 - 0.034 14.4 0.0 0.051 13.8 0.0 1.3 1 0 0 1 1 1 0 SdrD B-like domain V-SNARE PF05008.15 PSC71761.1 - 0.037 14.4 0.3 0.06 13.7 0.3 1.3 1 0 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus CarboxypepD_reg PF13620.6 PSC71761.1 - 0.11 12.8 0.0 0.17 12.1 0.0 1.3 1 0 0 1 1 1 0 Carboxypeptidase regulatory-like domain DUF3551 PF12071.8 PSC71761.1 - 0.17 11.9 2.1 0.28 11.3 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3551) ThrE PF06738.12 PSC71761.1 - 0.18 11.2 0.1 0.29 10.5 0.1 1.3 1 0 0 1 1 1 0 Putative threonine/serine exporter Chloroa_b-bind PF00504.21 PSC71762.1 - 1.8e-36 126.1 0.0 3.5e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Cation_efflux PF01545.21 PSC71762.1 - 1.2e-11 44.7 12.7 1.4e-10 41.3 12.7 2.1 1 1 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 PSC71762.1 - 4.2e-09 36.4 0.0 9.2e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter LRR_8 PF13855.6 PSC71763.1 - 0.00055 19.6 0.0 0.97 9.2 0.0 3.6 2 1 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 PSC71763.1 - 0.00075 19.8 0.0 5.7 7.5 0.0 3.4 2 1 0 3 3 3 2 Leucine Rich repeats (2 copies) rve PF00665.26 PSC71764.1 - 1.3e-18 67.3 0.0 2.8e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC71764.1 - 0.012 15.4 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain MFS_MOT1 PF16983.5 PSC71765.1 - 1.6e-59 199.1 24.7 2.5e-33 114.8 6.4 5.0 5 0 0 5 5 5 2 Molybdate transporter of MFS superfamily Aldo_ket_red PF00248.21 PSC71765.1 - 6.4e-14 51.8 0.0 8.3e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Sulfate_transp PF00916.20 PSC71765.1 - 0.00019 20.3 9.3 0.00027 19.8 0.6 2.4 2 0 0 2 2 2 2 Sulfate permease family MFS_MOT1 PF16983.5 PSC71766.1 - 1.6e-59 199.2 24.7 2.5e-33 114.8 6.4 4.9 5 0 0 5 5 5 2 Molybdate transporter of MFS superfamily Aldo_ket_red PF00248.21 PSC71766.1 - 6.3e-14 51.9 0.0 8.2e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family Sulfate_transp PF00916.20 PSC71766.1 - 0.00019 20.3 9.3 0.00027 19.8 0.6 2.4 2 0 0 2 2 2 2 Sulfate permease family Voltage_CLC PF00654.20 PSC71767.1 - 6.4e-58 196.7 35.9 6.4e-58 196.7 35.9 2.4 2 1 0 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 PSC71767.1 - 9.8e-08 32.3 0.0 0.00075 19.9 0.0 2.4 2 0 0 2 2 2 2 CBS domain Fe-S_biosyn PF01521.20 PSC71768.1 - 3e-20 72.5 0.0 5.2e-20 71.7 0.0 1.4 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF1345 PF07077.11 PSC71768.1 - 0.63 9.7 8.0 0.24 11.1 4.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1345) DUF1995 PF09353.10 PSC71769.1 - 3e-31 109.0 0.0 3e-31 109.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1995) DnaJ_CXXCXGXG PF00684.19 PSC71769.1 - 0.8 10.1 5.8 1.9 8.9 1.1 2.5 2 0 0 2 2 2 0 DnaJ central domain Rieske PF00355.26 PSC71770.1 - 1.6e-33 114.5 3.6 6.3e-16 58.1 0.3 2.5 2 0 0 2 2 2 2 Rieske [2Fe-2S] domain FAD_binding_3 PF01494.19 PSC71770.1 - 3e-17 62.9 0.2 4.3e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain FHA PF00498.26 PSC71770.1 - 6.1e-12 45.7 0.0 1.3e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 FHA domain Rieske_2 PF13806.6 PSC71770.1 - 9.1e-10 38.4 0.0 0.0023 17.8 0.0 2.6 2 0 0 2 2 2 2 Rieske-like [2Fe-2S] domain Yop-YscD_cpl PF16697.5 PSC71770.1 - 8.8e-07 29.2 0.0 1.9e-06 28.1 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain NAD_binding_8 PF13450.6 PSC71770.1 - 0.00039 20.6 0.6 0.0019 18.4 0.6 2.3 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PSC71770.1 - 0.0013 18.4 1.4 0.0096 15.5 1.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PSC71770.1 - 0.017 14.4 1.3 0.12 11.6 0.6 2.5 2 1 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase HYLS1_C PF15311.6 PSC71770.1 - 0.044 14.5 1.0 5.4 7.8 0.1 2.5 2 0 0 2 2 2 0 Hydrolethalus syndrome protein 1 C-terminus Tape_meas_lam_C PF09718.10 PSC71770.1 - 0.053 13.6 0.0 23 5.2 0.0 2.9 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Phycobilisome PF00502.19 PSC71770.1 - 0.13 12.2 0.0 10 6.0 0.0 2.5 2 0 0 2 2 2 0 Phycobilisome protein Pyr_redox PF00070.27 PSC71770.1 - 0.34 11.5 1.1 0.86 10.2 1.1 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase UBA_4 PF14555.6 PSC71771.1 - 0.034 14.0 0.4 11 5.9 0.0 2.9 2 0 0 2 2 2 0 UBA-like domain DUF3357 PF11837.8 PSC71771.1 - 8.9 6.8 10.9 2.1 8.8 0.2 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF3357) PA14 PF07691.12 PSC71772.1 - 1.1e-18 67.4 0.0 1.8e-08 34.3 0.0 2.3 2 0 0 2 2 2 2 PA14 domain GLEYA PF10528.9 PSC71772.1 - 1.2e-05 25.7 2.6 0.0048 17.3 0.2 3.1 3 0 0 3 3 3 2 GLEYA domain RRM_1 PF00076.22 PSC71773.1 - 1e-19 70.1 0.0 1.9e-19 69.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PSC71773.1 - 0.002 17.7 0.0 0.0028 17.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PSC71773.1 - 0.0025 17.6 0.0 0.0051 16.6 0.0 1.5 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 PSC71773.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.5 1 1 0 1 1 1 0 RNA recognition motif OB_RNB PF08206.11 PSC71773.1 - 0.12 12.1 0.2 0.31 10.8 0.0 1.8 2 0 0 2 2 2 0 Ribonuclease B OB domain PP2C PF00481.21 PSC71774.1 - 6.9e-55 186.5 0.4 4e-51 174.1 0.4 2.3 2 0 0 2 2 2 2 Protein phosphatase 2C Acyl-CoA_dh_1 PF00441.24 PSC71774.1 - 6e-24 85.0 2.1 6e-24 85.0 2.1 3.0 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 PSC71774.1 - 1.2e-20 74.0 0.8 4.2e-20 72.3 0.0 2.4 2 0 0 2 2 2 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 PSC71774.1 - 1.3e-11 44.5 0.2 5.6e-11 42.5 0.0 2.2 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain SpoIIE PF07228.12 PSC71774.1 - 0.041 13.8 4.1 0.84 9.5 0.1 3.1 3 0 0 3 3 3 0 Stage II sporulation protein E (SpoIIE) TFIIA PF03153.13 PSC71774.1 - 2.2 8.2 22.5 0.098 12.6 5.7 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PSCyt3 PF07627.11 PSC71775.1 - 0.39 11.0 8.1 14 6.0 0.4 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1588) ABC_tran PF00005.27 PSC71777.1 - 6.7e-36 123.8 0.0 1.1e-35 123.1 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 PSC71777.1 - 9.5e-36 123.8 2.2 1.4e-35 123.3 2.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 PSC71777.1 - 3.3e-08 33.2 0.2 1.1e-06 28.2 0.2 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PSC71777.1 - 0.00012 22.5 0.1 0.00044 20.7 0.1 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 PSC71777.1 - 0.0058 16.3 1.3 0.021 14.5 0.3 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 PSC71777.1 - 0.011 15.6 0.0 0.028 14.2 0.0 1.6 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 PSC71777.1 - 0.011 16.0 0.0 0.051 13.9 0.0 2.0 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 PSC71777.1 - 0.015 15.4 0.0 0.03 14.4 0.0 1.4 1 0 0 1 1 1 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 PSC71777.1 - 0.026 14.6 0.0 0.087 12.9 0.0 1.9 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_5 PF07728.14 PSC71777.1 - 0.031 14.3 0.1 0.59 10.1 0.1 2.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF815 PF05673.13 PSC71777.1 - 0.048 12.8 0.0 0.082 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.18 PSC71777.1 - 0.075 12.4 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_23 PF13476.6 PSC71777.1 - 0.11 13.0 0.1 0.22 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain DUF1659 PF07872.11 PSC71777.1 - 0.11 12.2 0.7 2.5 7.8 0.4 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1659) RsgA_GTPase PF03193.16 PSC71777.1 - 0.14 12.0 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase DUF3561 PF12084.8 PSC71777.1 - 0.21 11.6 2.8 0.89 9.6 2.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3561) AAA_30 PF13604.6 PSC71777.1 - 0.41 10.4 4.7 0.31 10.7 0.2 2.6 2 1 0 2 2 2 0 AAA domain Pkinase_Tyr PF07714.17 PSC71778.1 - 2e-50 171.5 0.0 5.5e-50 170.1 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC71778.1 - 1.6e-46 158.8 0.0 3.5e-46 157.7 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain PAN_4 PF14295.6 PSC71778.1 - 4.7e-12 45.6 20.8 0.00054 19.8 2.6 4.5 4 0 0 4 4 4 4 PAN domain Kinase-like PF14531.6 PSC71778.1 - 0.0061 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like MHYT PF03707.16 PSC71778.1 - 1.7 8.9 9.9 12 6.1 2.4 3.0 2 0 0 2 2 2 0 Bacterial signalling protein N terminal repeat TFIIA PF03153.13 PSC71778.1 - 2 8.3 18.2 1 9.3 3.7 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SKG6 PF08693.10 PSC71778.1 - 3.1 7.3 9.1 11 5.5 9.1 2.0 1 0 0 1 1 1 0 Transmembrane alpha-helix domain AWPM-19 PF05512.11 PSC71778.1 - 3.5 7.8 5.9 0.24 11.6 0.2 1.9 2 0 0 2 2 2 0 AWPM-19-like family SAP PF02037.27 PSC71779.1 - 1.7e-08 34.0 1.9 3.2e-05 23.5 0.0 2.4 2 0 0 2 2 2 2 SAP domain SAP PF02037.27 PSC71780.1 - 1.7e-08 34.0 1.9 3.2e-05 23.6 0.0 2.4 2 0 0 2 2 2 2 SAP domain MFS_1_like PF12832.7 PSC71781.1 - 4.1e-41 141.1 3.4 9.2e-31 107.1 1.3 2.2 2 0 0 2 2 2 2 MFS_1 like family MFS_1 PF07690.16 PSC71781.1 - 9.3e-12 44.5 39.6 6.4e-07 28.6 19.8 3.1 2 0 0 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 PSC71781.1 - 8.1e-05 21.8 0.5 8.1e-05 21.8 0.5 1.9 2 0 0 2 2 2 1 Nucleoside H+ symporter Nup160 PF11715.8 PSC71781.1 - 0.0009 18.0 0.0 0.011 14.4 0.0 2.2 1 1 0 1 1 1 1 Nucleoporin Nup120/160 Sugar_tr PF00083.24 PSC71781.1 - 0.14 11.0 6.6 1.1 8.0 6.5 2.1 1 1 0 1 1 1 0 Sugar (and other) transporter ABC_membrane PF00664.23 PSC71782.1 - 1.9e-51 175.3 14.4 2.1e-29 103.0 4.6 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PSC71782.1 - 4.4e-45 153.6 0.0 1.3e-22 80.7 0.0 2.4 2 0 0 2 2 2 2 ABC transporter MMR_HSR1 PF01926.23 PSC71782.1 - 1.4e-05 25.2 0.3 0.085 12.9 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 PSC71782.1 - 2.6e-05 24.7 1.4 0.23 11.8 0.1 2.9 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 PSC71782.1 - 4.2e-05 23.1 0.5 1.2 8.6 0.0 4.0 3 1 0 4 4 4 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PSC71782.1 - 0.0001 21.9 2.2 0.12 12.2 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 PSC71782.1 - 0.00013 21.9 0.1 0.04 13.8 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 PSC71782.1 - 0.00072 20.1 0.0 0.12 12.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 PSC71782.1 - 0.00089 19.1 2.1 4.6 7.0 0.3 3.8 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 PSC71782.1 - 0.0015 18.8 0.3 0.64 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 PSC71782.1 - 0.0019 18.3 1.0 0.055 13.5 0.1 2.3 2 0 0 2 2 2 1 Dynamin family DUF87 PF01935.17 PSC71782.1 - 0.0024 18.0 3.2 0.12 12.4 0.3 2.2 2 0 0 2 2 2 1 Helicase HerA, central domain AAA_7 PF12775.7 PSC71782.1 - 0.053 13.0 0.2 3.4 7.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region TrwB_AAD_bind PF10412.9 PSC71782.1 - 0.13 11.1 0.1 3.7 6.4 0.0 2.1 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain FHIPEP PF00771.20 PSC71782.1 - 0.14 10.6 0.1 0.27 9.7 0.1 1.4 1 0 0 1 1 1 0 FHIPEP family Zeta_toxin PF06414.12 PSC71782.1 - 0.16 11.2 0.6 0.87 8.8 0.1 2.1 2 0 0 2 2 2 0 Zeta toxin T2SSE PF00437.20 PSC71782.1 - 0.16 11.0 0.0 16 4.4 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein Fez1 PF06818.15 PSC71783.1 - 0.0019 18.7 0.3 0.0019 18.7 0.3 12.5 6 4 5 11 11 11 6 Fez1 ZapB PF06005.12 PSC71783.1 - 0.0082 16.6 2.1 0.0082 16.6 2.1 22.2 15 5 3 20 20 20 5 Cell division protein ZapB Aa_trans PF01490.18 PSC71785.1 - 1.4e-29 103.0 11.7 1.7e-29 102.8 11.7 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Peptidase_S8 PF00082.22 PSC71786.1 - 2.5e-37 128.7 6.3 4.9e-37 127.8 6.3 1.4 1 0 0 1 1 1 1 Subtilase family Sacchrp_dh_NADP PF03435.18 PSC71786.1 - 0.12 12.6 0.1 0.23 11.7 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain C2 PF00168.30 PSC71787.1 - 6.9e-08 32.7 0.0 9.3e-06 25.9 0.0 2.4 2 0 0 2 2 2 2 C2 domain TMF_TATA_bd PF12325.8 PSC71788.1 - 6.7e-13 48.9 11.6 6.7e-13 48.9 11.6 7.0 2 1 5 7 7 7 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 PSC71788.1 - 1.9e-10 40.6 4.3 1.9e-10 40.6 4.3 8.5 5 3 3 8 8 8 1 TATA element modulatory factor 1 DNA binding DUF4763 PF15960.5 PSC71788.1 - 0.0019 17.6 2.6 0.0019 17.6 2.6 5.8 3 2 2 5 5 5 3 Domain of unknown function (DUF4763) CCDC144C PF14915.6 PSC71788.1 - 0.0091 15.1 0.8 0.0091 15.1 0.8 5.5 2 2 2 5 5 5 1 CCDC144C protein coiled-coil region GH-E PF14410.6 PSC71789.1 - 0.00069 20.0 1.8 13 6.3 0.0 3.3 1 1 2 3 3 3 3 HNH/ENDO VII superfamily nuclease with conserved GHE residues PPTA PF01239.22 PSC71789.1 - 0.5 10.2 6.9 44 4.0 0.2 3.7 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat Flg_bb_rod PF00460.20 PSC71789.1 - 6.7 6.8 15.3 14 5.8 2.0 3.5 3 0 0 3 3 3 0 Flagella basal body rod protein Nramp PF01566.18 PSC71790.1 - 2.1e-94 316.5 8.9 2.1e-94 316.5 8.9 2.1 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein Peptidase_S10 PF00450.22 PSC71790.1 - 1e-73 249.2 0.0 2e-72 244.9 0.0 2.7 1 1 0 1 1 1 1 Serine carboxypeptidase COX6B PF02297.17 PSC71790.1 - 8.2e-08 32.4 7.3 1.7e-07 31.4 7.3 1.5 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb Peptidase_C1 PF00112.23 PSC71791.1 - 5.5e-40 137.8 0.0 1.1e-39 136.8 0.0 1.5 1 0 0 1 1 1 1 Papain family cysteine protease bZIP_2 PF07716.15 PSC71791.1 - 0.0011 19.0 5.6 0.0018 18.3 5.6 1.3 1 0 0 1 1 1 1 Basic region leucine zipper Inhibitor_I29 PF08246.12 PSC71791.1 - 0.002 18.5 0.0 0.0038 17.6 0.0 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) bZIP_1 PF00170.21 PSC71791.1 - 0.007 16.4 5.2 0.012 15.7 5.2 1.3 1 0 0 1 1 1 1 bZIP transcription factor Glyoxalase PF00903.25 PSC71792.1 - 5.6e-08 33.0 0.1 2.8e-07 30.8 0.1 2.0 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 PSC71792.1 - 1.4e-06 29.1 1.8 3.6e-06 27.7 0.0 2.2 2 1 0 2 2 2 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 PSC71792.1 - 2e-05 24.8 0.0 0.036 14.3 0.0 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 PSC71792.1 - 0.014 15.3 0.0 0.039 13.9 0.0 1.6 2 0 0 2 2 2 0 Glyoxalase-like domain Ldh_1_C PF02866.18 PSC71793.1 - 1.4e-32 112.9 0.0 2.4e-32 112.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 PSC71793.1 - 3.5e-32 111.4 0.5 5e-32 110.9 0.5 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Glyco_hydro_3_C PF01915.22 PSC71793.1 - 0.0021 18.1 0.0 0.0031 17.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain 3Beta_HSD PF01073.19 PSC71793.1 - 0.015 14.3 0.0 0.022 13.7 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family EF-hand_1 PF00036.32 PSC71794.1 - 1.5e-13 49.3 0.0 5e-07 28.8 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PSC71794.1 - 1.4e-11 43.4 0.1 2.6e-05 23.8 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 PSC71794.1 - 8.8e-09 35.7 0.0 1.5e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 PSC71794.1 - 1.1e-08 34.7 0.0 2.3e-05 24.1 0.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PSC71794.1 - 5.9e-07 28.7 0.0 0.0025 17.3 0.0 2.4 2 0 0 2 2 2 2 EF hand EF-hand_4 PF12763.7 PSC71794.1 - 0.00014 21.8 0.0 0.34 10.9 0.0 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_10 PF14788.6 PSC71794.1 - 0.046 13.6 0.0 2.9 7.8 0.0 2.3 2 0 0 2 2 2 0 EF hand EF-hand_9 PF14658.6 PSC71794.1 - 0.074 13.4 0.1 0.54 10.6 0.1 2.0 1 1 0 1 1 1 0 EF-hand domain SPARC_Ca_bdg PF10591.9 PSC71794.1 - 0.12 12.8 0.0 9.5 6.6 0.0 2.1 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region zf-UBR PF02207.20 PSC71795.1 - 7.1e-20 70.9 10.2 7.1e-20 70.9 10.2 2.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zf-RING_5 PF14634.6 PSC71795.1 - 0.018 15.0 0.6 0.018 15.0 0.6 2.8 3 0 0 3 3 3 0 zinc-RING finger domain zf-UBR PF02207.20 PSC71796.1 - 7.1e-20 70.9 10.2 7.1e-20 70.9 10.2 2.0 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zf-RING_5 PF14634.6 PSC71796.1 - 0.018 15.0 0.6 0.018 15.0 0.6 2.8 3 0 0 3 3 3 0 zinc-RING finger domain Glyco_transf_90 PF05686.12 PSC71797.1 - 4.9e-34 117.9 0.0 6.1e-34 117.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 Keratin_2_head PF16208.5 PSC71797.1 - 7 6.8 20.4 12 6.1 20.4 1.3 1 0 0 1 1 1 0 Keratin type II head MOSC_N PF03476.16 PSC71798.1 - 1e-21 77.0 0.0 1e-20 73.8 0.0 2.3 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 PSC71798.1 - 1.4e-21 76.9 0.0 3.1e-13 49.4 0.0 2.9 2 1 1 3 3 3 2 Aminotransferase class-V MOSC PF03473.17 PSC71798.1 - 1.2e-17 64.1 0.0 2.6e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 PSC71799.1 - 1e-21 77.0 0.0 1e-20 73.8 0.0 2.3 1 1 0 1 1 1 1 MOSC N-terminal beta barrel domain Aminotran_5 PF00266.19 PSC71799.1 - 1.4e-21 76.9 0.0 3.1e-13 49.4 0.0 2.9 2 1 1 3 3 3 2 Aminotransferase class-V MOSC PF03473.17 PSC71799.1 - 1.2e-17 64.1 0.0 2.6e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 MOSC domain FYRC PF05965.14 PSC71800.1 - 6.6e-18 64.7 0.0 1.6e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus FYRN PF05964.14 PSC71800.1 - 2.1e-05 24.3 0.0 3.5e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 F/Y-rich N-terminus U-box PF04564.15 PSC71800.1 - 0.0013 18.8 0.0 0.0026 17.9 0.0 1.4 1 0 0 1 1 1 1 U-box domain stn_TNFRSF12A PF12191.8 PSC71800.1 - 1.5 9.0 7.5 0.076 13.2 0.5 2.5 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain LysM PF01476.20 PSC71801.1 - 1.1e-13 51.0 0.0 1.3e-13 50.8 0.0 1.1 1 0 0 1 1 1 1 LysM domain DAP_epimerase PF01678.19 PSC71802.1 - 4.2e-60 201.3 0.0 4.6e-32 110.7 0.0 2.2 2 0 0 2 2 2 2 Diaminopimelate epimerase Glyco_transf_49 PF13896.6 PSC71803.1 - 4.3e-23 82.2 0.2 3.1e-15 56.4 0.0 2.3 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan RskA PF10099.9 PSC71803.1 - 0.0073 16.6 5.4 0.0073 16.6 5.4 4.7 4 2 0 4 4 4 1 Anti-sigma-K factor rskA ANAPC5 PF12862.7 PSC71803.1 - 0.076 13.1 0.3 0.18 11.9 0.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 5 DUF3357 PF11837.8 PSC71803.1 - 6.4 7.3 8.2 1.5 9.3 0.3 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3357) Vps51 PF08700.11 PSC71806.1 - 2.5e-21 75.5 0.0 5.6e-21 74.4 0.0 1.6 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.6 PSC71806.1 - 1.6e-12 47.7 0.0 2.5e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Exocyst complex component Sec5 Dor1 PF04124.12 PSC71806.1 - 5.6e-08 31.9 0.1 1e-07 31.0 0.1 1.3 1 0 0 1 1 1 1 Dor1-like family COG2 PF06148.11 PSC71806.1 - 2.4e-06 27.7 0.1 6.2e-06 26.3 0.1 1.7 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 PSC71806.1 - 0.16 12.1 0.0 0.57 10.4 0.0 2.0 1 0 0 1 1 1 0 Golgi transport complex subunit 5 Zw10 PF06248.13 PSC71806.1 - 0.16 10.5 0.0 0.25 9.9 0.0 1.1 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 EamA PF00892.20 PSC71807.1 - 6.4e-22 78.2 20.6 1.2e-12 48.1 9.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family Peptidase_S8 PF00082.22 PSC71808.1 - 9.7e-25 87.4 13.4 9.7e-25 87.4 13.4 2.3 2 1 1 3 3 3 1 Subtilase family DUF3391 PF11871.8 PSC71810.1 - 1.2 9.7 4.2 1.9 9.0 4.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) HLH PF00010.26 PSC71812.1 - 3.6e-05 23.6 0.0 7.4e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Leu_zip PF15294.6 PSC71812.1 - 0.81 9.2 5.0 0.9 9.0 1.2 2.2 2 0 0 2 2 2 0 Leucine zipper Fez1 PF06818.15 PSC71812.1 - 5.2 7.5 15.4 0.18 12.2 0.7 2.3 2 0 0 2 2 2 0 Fez1 Ribonuclease_T2 PF00445.18 PSC71813.1 - 6.6e-30 104.7 0.0 1.2e-29 103.9 0.0 1.4 1 1 0 1 1 1 1 Ribonuclease T2 family zf-Nse PF11789.8 PSC71813.1 - 0.014 15.2 1.6 0.03 14.1 1.6 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.25 PSC71813.1 - 0.21 11.5 5.1 0.17 11.7 1.3 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC71813.1 - 4 7.8 7.9 0.38 11.1 2.6 2.2 2 0 0 2 2 2 0 Ring finger domain bZIP_1 PF00170.21 PSC71814.1 - 0.022 14.9 1.3 0.022 14.9 1.3 9.5 12 1 1 13 13 13 0 bZIP transcription factor Oxidored_molyb PF00174.19 PSC71816.1 - 2.1e-58 196.7 0.0 3.4e-58 196.0 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 PSC71816.1 - 1.2e-44 151.6 0.2 2.1e-44 150.9 0.2 1.4 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain FAD_binding_6 PF00970.24 PSC71816.1 - 2.8e-36 123.8 0.0 7.2e-36 122.5 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 PSC71816.1 - 1.1e-30 106.4 0.0 2.3e-30 105.4 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Cyt-b5 PF00173.28 PSC71816.1 - 7.3e-24 83.7 0.0 1.4e-23 82.8 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_6 PF08030.12 PSC71816.1 - 0.014 15.5 0.0 0.035 14.2 0.0 1.7 1 0 0 1 1 1 0 Ferric reductase NAD binding domain DFP PF04127.15 PSC71817.1 - 3.7e-14 53.0 0.0 7.6e-09 35.7 0.0 2.6 1 1 1 2 2 2 2 DNA / pantothenate metabolism flavoprotein Peptidase_M1 PF01433.20 PSC71817.1 - 0.0018 17.9 0.0 0.0056 16.3 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 PSC71817.1 - 0.015 15.5 0.0 0.038 14.2 0.0 1.5 2 0 0 2 2 2 0 Peptidase M1 N-terminal domain MOSC_N PF03476.16 PSC71817.1 - 0.13 12.2 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 MOSC N-terminal beta barrel domain DUF1338 PF07063.13 PSC71818.1 - 3.6e-68 230.1 0.0 2.8e-67 227.2 0.0 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF1338) E1-E2_ATPase PF00122.20 PSC71819.1 - 2.5e-50 170.5 1.5 2.5e-50 170.5 1.5 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 PSC71819.1 - 4.4e-47 160.2 1.0 8.4e-47 159.2 1.0 1.5 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 PSC71819.1 - 1.7e-22 80.7 9.9 3e-20 73.4 6.1 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PSC71819.1 - 7.2e-21 74.1 0.0 1.3e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 PSC71819.1 - 2.3e-18 65.6 0.0 5.3e-18 64.5 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PSC71819.1 - 2.7e-07 30.6 1.2 3.4e-05 23.7 0.8 2.2 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 PSC71819.1 - 0.004 17.6 0.2 0.04 14.3 0.1 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase T2SSM PF04612.12 PSC71821.1 - 0.0068 16.5 0.1 0.0077 16.3 0.1 1.1 1 0 0 1 1 1 1 Type II secretion system (T2SS), protein M Alpha-amylase PF00128.24 PSC71822.1 - 1.8e-28 100.1 0.0 5.4e-28 98.5 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glycos_transf_1 PF00534.20 PSC71822.1 - 7.7e-09 35.3 0.0 1.8e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 IFT46_B_C PF12317.8 PSC71823.1 - 4.9e-50 170.2 0.0 6.1e-50 169.9 0.0 1.0 1 0 0 1 1 1 1 Intraflagellar transport complex B protein 46 C terminal Amino_oxidase PF01593.24 PSC71824.1 - 1.7e-62 212.2 0.2 4.1e-61 207.7 0.2 2.1 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PSC71824.1 - 1.3e-12 47.7 0.1 7.3e-12 45.3 0.1 2.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain B3 PF02362.21 PSC71824.1 - 1.6e-07 31.1 0.0 2.9e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 B3 DNA binding domain Pyr_redox PF00070.27 PSC71824.1 - 1.1e-06 29.1 0.4 2.4e-06 28.0 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 PSC71824.1 - 1.7e-06 27.5 2.2 3.5e-06 26.5 2.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 PSC71824.1 - 5.5e-06 25.8 0.1 1.2e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PSC71824.1 - 0.00063 18.5 0.9 0.00098 17.9 0.9 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 PSC71824.1 - 0.0019 17.4 0.3 0.0028 16.8 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 PSC71824.1 - 0.14 11.4 0.3 0.24 10.6 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PSC71824.1 - 0.14 11.4 0.7 0.28 10.4 0.7 1.4 1 0 0 1 1 1 0 Thi4 family Amino_oxidase PF01593.24 PSC71825.1 - 1.1e-62 212.9 0.1 4.3e-62 210.9 0.1 1.9 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PSC71825.1 - 1.3e-12 47.7 0.1 7.3e-12 45.3 0.1 2.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain B3 PF02362.21 PSC71825.1 - 1.6e-07 31.1 0.0 2.9e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 B3 DNA binding domain Pyr_redox PF00070.27 PSC71825.1 - 1.1e-06 29.1 0.4 2.4e-06 28.0 0.4 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 PSC71825.1 - 1.7e-06 27.5 2.2 3.5e-06 26.5 2.2 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 PSC71825.1 - 5.5e-06 25.8 0.1 1.2e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PSC71825.1 - 0.00064 18.5 0.9 0.00098 17.9 0.9 1.2 1 0 0 1 1 1 1 HI0933-like protein GIDA PF01134.22 PSC71825.1 - 0.0019 17.4 0.3 0.0028 16.8 0.3 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 PSC71825.1 - 0.14 11.4 0.3 0.24 10.6 0.3 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PSC71825.1 - 0.14 11.4 0.7 0.28 10.4 0.7 1.4 1 0 0 1 1 1 0 Thi4 family GDPD PF03009.17 PSC71826.1 - 7.4e-52 176.6 0.0 1.5e-51 175.6 0.0 1.6 1 0 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family Peptidase_C1 PF00112.23 PSC71826.1 - 5.1e-37 128.1 0.0 1e-36 127.1 0.0 1.5 1 0 0 1 1 1 1 Papain family cysteine protease GN3L_Grn1 PF08701.11 PSC71826.1 - 1.7e-18 66.5 19.8 5.5e-18 64.8 19.8 1.9 1 0 0 1 1 1 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 PSC71826.1 - 2.8e-16 59.6 0.1 1e-14 54.5 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PSC71826.1 - 2.6e-10 40.0 0.0 3.8e-08 33.0 0.1 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PSC71826.1 - 5.1e-05 23.2 0.2 0.075 12.9 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 PSC71826.1 - 0.0063 16.6 2.3 0.0066 16.5 0.0 2.2 2 0 0 2 2 2 1 Dynamin family GTP_EFTU PF00009.27 PSC71826.1 - 0.01 15.4 0.2 0.09 12.3 0.1 2.4 2 1 0 3 3 3 0 Elongation factor Tu GTP binding domain AIG1 PF04548.16 PSC71826.1 - 0.078 12.3 0.0 0.21 10.9 0.0 1.7 1 0 0 1 1 1 0 AIG1 family Inhibitor_I29 PF08246.12 PSC71826.1 - 0.12 12.8 0.0 0.37 11.3 0.0 1.8 1 0 0 1 1 1 0 Cathepsin propeptide inhibitor domain (I29) Arf PF00025.21 PSC71826.1 - 0.29 10.6 0.4 1.6 8.2 0.1 2.1 2 0 0 2 2 2 0 ADP-ribosylation factor family Methyltransf_16 PF10294.9 PSC71827.1 - 3.3e-20 72.5 0.0 3.1e-11 43.3 0.0 2.1 2 0 0 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 PSC71827.1 - 9.3e-07 28.8 0.5 1.8e-06 27.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PSC71827.1 - 0.00018 21.1 0.0 0.00028 20.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 PSC71827.1 - 0.0094 16.6 0.0 0.076 13.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC71827.1 - 0.044 14.5 0.0 3.3 8.5 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain TehB PF03848.14 PSC71827.1 - 0.064 12.7 0.0 0.099 12.0 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_11 PF08241.12 PSC71827.1 - 0.072 13.7 0.0 1.1 10.0 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 PSC71827.1 - 0.15 11.8 0.0 0.64 9.8 0.1 1.9 2 0 0 2 2 2 0 Methyltransferase domain Bax1-I PF01027.20 PSC71828.1 - 0.42 10.4 1.3 0.74 9.6 1.3 1.3 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 REV PF00424.18 PSC71829.1 - 0.029 14.4 0.7 0.059 13.4 0.7 1.5 1 0 0 1 1 1 0 REV protein (anti-repression trans-activator protein) Fez1 PF06818.15 PSC71830.1 - 0.00029 21.4 0.4 0.00047 20.7 0.4 1.2 1 0 0 1 1 1 1 Fez1 DUF4201 PF13870.6 PSC71830.1 - 0.015 15.0 2.5 0.022 14.5 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) DUF641 PF04859.12 PSC71830.1 - 0.042 14.2 1.7 0.069 13.5 1.7 1.3 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) End3 PF12761.7 PSC71830.1 - 0.063 13.4 0.5 0.063 13.4 0.5 1.8 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 APG6_N PF17675.1 PSC71830.1 - 0.12 12.9 6.3 0.17 12.4 6.3 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region TMF_TATA_bd PF12325.8 PSC71830.1 - 0.16 12.2 4.2 0.25 11.6 4.2 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding Cep57_MT_bd PF06657.13 PSC71830.1 - 0.55 10.7 4.2 0.89 10.0 3.5 1.7 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 TSNAXIP1_N PF15739.5 PSC71830.1 - 0.55 10.6 2.6 0.89 9.9 2.6 1.3 1 0 0 1 1 1 0 Translin-associated factor X-interacting N-terminus Spc7 PF08317.11 PSC71830.1 - 0.79 8.5 5.6 1.1 8.1 5.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIC PF04977.15 PSC71830.1 - 1.6 8.6 3.8 3.3 7.5 3.5 1.6 1 1 0 1 1 1 0 Septum formation initiator YukD PF08817.10 PSC71831.1 - 0.066 13.9 0.0 0.15 12.8 0.0 1.6 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Peptidase_S8 PF00082.22 PSC71832.1 - 1.2e-34 119.9 6.2 1.7e-34 119.4 6.2 1.2 1 0 0 1 1 1 1 Subtilase family E2F_TDP PF02319.20 PSC71833.1 - 1.1e-24 86.2 0.0 1.1e-11 44.7 0.0 2.5 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain HATPase_c PF02518.26 PSC71833.1 - 4.5e-23 81.9 0.0 5.3e-22 78.5 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PSC71833.1 - 1.2e-20 73.8 1.9 1.5e-18 67.0 0.0 3.9 4 0 0 4 4 3 1 Response regulator receiver domain PAS_9 PF13426.7 PSC71833.1 - 1.6e-17 63.6 0.0 3.5e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 PAS domain HisKA PF00512.25 PSC71833.1 - 5.3e-15 55.2 0.4 1.8e-14 53.5 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 PSC71833.1 - 9e-06 25.9 0.1 5.4e-05 23.4 0.0 2.6 2 0 0 2 2 1 1 PAS fold PAS_8 PF13188.7 PSC71833.1 - 0.0021 18.0 0.0 0.0072 16.3 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 PSC71833.1 - 0.0046 17.0 0.0 0.065 13.2 0.0 2.6 1 1 0 1 1 1 1 PAS fold PAS_3 PF08447.12 PSC71833.1 - 0.0055 17.0 0.0 0.031 14.5 0.0 2.4 2 1 0 2 2 2 1 PAS fold DUF4611 PF15387.6 PSC71833.1 - 0.011 15.9 9.5 1.7 9.0 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF2052 PF09747.9 PSC71833.1 - 0.039 14.1 13.6 0.49 10.5 4.4 3.3 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) HATPase_c_3 PF13589.6 PSC71833.1 - 0.14 11.9 0.0 0.3 10.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAT1 PF09770.9 PSC71833.1 - 1.7 6.8 7.6 2.7 6.1 7.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM176 PF14851.6 PSC71833.1 - 2.4 7.8 8.5 1.7 8.3 2.5 2.5 2 0 0 2 2 2 0 FAM176 family CDC45 PF02724.14 PSC71833.1 - 2.8 6.1 7.2 0.61 8.3 2.6 2.0 2 0 0 2 2 2 0 CDC45-like protein BSP_II PF05432.11 PSC71833.1 - 6.3 6.4 16.0 2 8.1 5.0 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) E2F_TDP PF02319.20 PSC71834.1 - 1.1e-24 86.2 0.0 1.1e-11 44.7 0.0 2.5 2 0 0 2 2 2 2 E2F/DP family winged-helix DNA-binding domain HATPase_c PF02518.26 PSC71834.1 - 4.5e-23 81.9 0.0 5.3e-22 78.5 0.0 2.3 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PSC71834.1 - 1.2e-20 73.8 1.9 1.5e-18 67.0 0.0 3.9 4 0 0 4 4 3 1 Response regulator receiver domain PAS_9 PF13426.7 PSC71834.1 - 1.6e-17 63.7 0.0 3.5e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 PAS domain HisKA PF00512.25 PSC71834.1 - 5.4e-15 55.2 0.4 1.8e-14 53.5 0.0 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 PSC71834.1 - 9.1e-06 25.9 0.1 5.4e-05 23.4 0.0 2.6 2 0 0 2 2 1 1 PAS fold PAS_8 PF13188.7 PSC71834.1 - 0.0022 18.0 0.0 0.0072 16.3 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 PSC71834.1 - 0.0046 17.0 0.0 0.065 13.2 0.0 2.6 1 1 0 1 1 1 1 PAS fold PAS_3 PF08447.12 PSC71834.1 - 0.0055 17.0 0.0 0.031 14.5 0.0 2.4 2 1 0 2 2 2 1 PAS fold DUF4611 PF15387.6 PSC71834.1 - 0.011 15.9 9.5 1.7 9.0 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF2052 PF09747.9 PSC71834.1 - 0.041 14.0 13.6 0.49 10.5 4.4 3.3 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) HATPase_c_3 PF13589.6 PSC71834.1 - 0.14 12.0 0.0 0.29 10.9 0.0 1.4 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAT1 PF09770.9 PSC71834.1 - 1.4 7.1 7.0 2.2 6.4 7.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM176 PF14851.6 PSC71834.1 - 2.4 7.8 8.5 1.7 8.3 2.5 2.5 2 0 0 2 2 2 0 FAM176 family CDC45 PF02724.14 PSC71834.1 - 2.8 6.1 7.2 0.61 8.3 2.6 1.9 2 0 0 2 2 2 0 CDC45-like protein BSP_II PF05432.11 PSC71834.1 - 6.3 6.4 16.0 2 8.1 5.0 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF2722 PF10846.8 PSC71835.1 - 1.2 8.0 10.7 2.7 6.8 10.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) FTZ PF03867.14 PSC71835.1 - 7.2 6.1 6.9 16 4.9 6.9 1.5 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region FUSC_2 PF13515.6 PSC71836.1 - 5.5e-06 26.5 10.9 5.5e-06 26.5 10.9 4.8 4 1 0 4 4 4 2 Fusaric acid resistance protein-like SCAMP PF04144.13 PSC71837.1 - 0.078 13.3 0.8 0.15 12.3 0.8 1.5 1 0 0 1 1 1 0 SCAMP family Abhydrolase_2 PF02230.16 PSC71839.1 - 1.2e-44 152.7 0.0 1.3e-44 152.6 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase DLH PF01738.18 PSC71839.1 - 3.9e-09 36.4 0.0 4.9e-09 36.1 0.0 1.1 1 0 0 1 1 1 1 Dienelactone hydrolase family FSH1 PF03959.13 PSC71839.1 - 4.7e-08 32.9 0.0 1.3e-07 31.5 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 PSC71839.1 - 3.2e-07 31.2 9.8 5.5e-07 30.4 9.8 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PSC71839.1 - 4.2e-06 26.2 0.1 0.015 14.6 0.0 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 PSC71839.1 - 5.2e-06 26.1 0.1 0.002 17.6 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 PSC71839.1 - 0.00018 21.4 0.0 0.00024 20.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 PSC71839.1 - 0.00034 20.5 0.2 0.0094 15.8 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 PSC71839.1 - 0.017 14.8 0.1 0.11 12.1 0.1 2.2 1 1 1 2 2 2 0 alpha/beta hydrolase fold Cutinase PF01083.22 PSC71839.1 - 0.018 15.0 0.0 0.024 14.6 0.0 1.2 1 0 0 1 1 1 0 Cutinase Esterase_phd PF10503.9 PSC71839.1 - 0.034 13.6 0.4 0.59 9.6 0.2 2.0 1 1 1 2 2 2 0 Esterase PHB depolymerase DUF2974 PF11187.8 PSC71839.1 - 0.081 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) AXE1 PF05448.12 PSC71839.1 - 0.095 11.4 0.1 0.13 10.9 0.1 1.2 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Lipase_3 PF01764.25 PSC71839.1 - 0.19 11.6 0.0 0.29 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipase (class 3) ABC_membrane PF00664.23 PSC71840.1 - 3.8e-36 125.1 2.0 4.8e-36 124.8 2.0 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 PSC71840.1 - 1.5e-31 109.8 0.0 2.8e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 PSC71840.1 - 3.7e-05 24.2 0.2 3.7e-05 24.2 0.2 1.9 2 0 0 2 2 1 1 AAA ATPase domain SMC_N PF02463.19 PSC71840.1 - 0.00013 21.5 0.1 0.0055 16.2 0.1 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 PSC71840.1 - 0.00068 19.9 0.0 0.0065 16.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 PSC71840.1 - 0.0038 16.9 0.2 0.0088 15.8 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_24 PF13479.6 PSC71840.1 - 0.0069 16.1 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PSC71840.1 - 0.025 15.1 0.0 0.12 13.0 0.0 2.0 2 1 0 2 2 2 0 AAA domain DUF815 PF05673.13 PSC71840.1 - 0.057 12.6 0.0 0.097 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 PSC71840.1 - 0.12 11.6 0.1 0.52 9.5 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_21 PF13304.6 PSC71840.1 - 0.14 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 PSC71840.1 - 0.14 12.2 0.0 0.3 11.2 0.0 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain AAA PF00004.29 PSC71840.1 - 0.15 12.5 0.0 2 8.9 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 PSC71840.1 - 0.16 11.9 0.1 0.43 10.5 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 PSC71841.1 - 1.5e-71 239.0 0.0 5.5e-40 136.8 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PALP PF00291.25 PSC71841.1 - 3.8e-34 118.5 0.0 3.8e-34 118.5 0.0 2.7 2 1 0 3 3 2 1 Pyridoxal-phosphate dependent enzyme AAA_16 PF13191.6 PSC71841.1 - 1.1e-11 45.4 0.5 0.00033 21.1 0.0 4.2 2 2 1 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 PSC71841.1 - 6.8e-10 38.9 0.0 0.00058 19.6 0.0 2.8 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PSC71841.1 - 1.6e-09 37.9 0.0 2e-05 24.6 0.0 3.2 3 1 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 PSC71841.1 - 4.6e-09 35.9 1.7 1.6e-08 34.2 1.7 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_33 PF13671.6 PSC71841.1 - 2.7e-07 30.8 0.0 0.0072 16.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 PSC71841.1 - 8.9e-07 29.3 0.0 0.05 13.9 0.0 3.6 2 2 2 4 4 4 2 AAA domain TIP49 PF06068.13 PSC71841.1 - 9.6e-06 25.0 0.1 0.036 13.3 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_2 PF07724.14 PSC71841.1 - 1.5e-05 25.2 0.0 0.065 13.4 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 PSC71841.1 - 2.1e-05 24.0 0.6 0.027 13.9 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 PSC71841.1 - 4.3e-05 23.3 0.0 0.079 12.7 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_28 PF13521.6 PSC71841.1 - 6.4e-05 23.3 0.0 0.027 14.7 0.0 2.9 3 0 0 3 3 2 1 AAA domain TsaE PF02367.17 PSC71841.1 - 0.0012 18.8 0.0 0.64 10.0 0.0 2.3 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 PSC71841.1 - 0.0022 17.9 0.1 0.8 9.6 0.0 2.9 3 0 0 3 3 3 1 NACHT domain RNA_helicase PF00910.22 PSC71841.1 - 0.0039 17.6 0.0 1.9 8.9 0.0 2.4 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.6 PSC71841.1 - 0.0045 16.6 2.4 0.26 10.9 0.3 3.2 2 2 1 3 3 3 1 AAA domain AAA_14 PF13173.6 PSC71841.1 - 0.013 15.5 0.0 2 8.5 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 PSC71841.1 - 0.014 15.3 0.0 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 PSC71841.1 - 0.015 15.0 0.7 0.88 9.2 1.6 2.8 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 PSC71841.1 - 0.017 14.9 0.0 5.7 6.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 PSC71841.1 - 0.018 14.5 0.3 0.46 9.9 0.3 2.2 2 0 0 2 2 2 0 PhoH-like protein AAA_24 PF13479.6 PSC71841.1 - 0.02 14.6 0.0 0.05 13.3 0.0 1.6 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.6 PSC71841.1 - 0.023 15.2 0.0 0.54 10.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 PSC71841.1 - 0.045 13.3 0.0 2 7.9 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 PSC71841.1 - 0.057 13.1 0.0 2.6 7.7 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain ATPase PF06745.13 PSC71841.1 - 0.059 12.7 0.0 2.7 7.3 0.0 2.2 2 0 0 2 2 2 0 KaiC SUIM_assoc PF16619.5 PSC71841.1 - 0.8 9.8 6.0 1.8 8.7 6.0 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 MoeA_N PF03453.17 PSC71843.1 - 6.1e-37 126.8 3.0 1.2e-36 125.9 3.0 1.5 1 0 0 1 1 1 1 MoeA N-terminal region (domain I and II) MoCF_biosynth PF00994.24 PSC71843.1 - 3.9e-25 88.2 0.0 6.7e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Probable molybdopterin binding domain MoeA_C PF03454.15 PSC71843.1 - 1.9e-14 53.6 0.3 8e-14 51.6 0.0 2.3 2 0 0 2 2 2 1 MoeA C-terminal region (domain IV) Peptidase_C1 PF00112.23 PSC71844.1 - 1.6e-39 136.3 0.0 2.3e-39 135.8 0.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PSC71844.1 - 0.00097 19.5 0.0 0.0016 18.8 0.0 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Pkinase_Tyr PF07714.17 PSC71845.1 - 5.1e-49 166.9 0.0 8.7e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC71845.1 - 8.9e-48 162.9 0.0 1.4e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 PSC71845.1 - 0.0009 19.2 8.6 0.001 19.0 0.1 3.1 2 1 1 3 3 3 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PSC71845.1 - 0.013 14.5 0.0 0.021 13.8 0.0 1.2 1 0 0 1 1 1 0 Haspin like kinase domain TFIIA PF03153.13 PSC71845.1 - 0.021 14.9 8.2 0.031 14.3 8.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CBM_3 PF00942.18 PSC71845.1 - 0.028 14.8 0.0 0.051 14.0 0.0 1.4 1 0 0 1 1 1 0 Cellulose binding domain CBM_2 PF00553.19 PSC71845.1 - 0.031 14.6 0.1 0.093 13.1 0.1 1.8 1 0 0 1 1 1 0 Cellulose binding domain Gram_pos_anchor PF00746.21 PSC71845.1 - 0.27 11.2 3.0 1.3 9.1 3.0 2.3 1 0 0 1 1 1 0 LPXTG cell wall anchor motif DAP10 PF07213.11 PSC71845.1 - 0.8 9.7 4.5 0.2 11.7 0.1 2.3 2 0 0 2 2 2 0 DAP10 membrane protein cobW PF02492.19 PSC71846.1 - 2.2e-59 200.0 0.2 3e-59 199.6 0.2 1.2 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 PSC71846.1 - 1.5e-18 66.5 0.0 3.2e-18 65.5 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.14 PSC71846.1 - 0.00044 20.2 0.1 0.0022 17.9 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B RsgA_GTPase PF03193.16 PSC71846.1 - 0.00075 19.4 0.0 0.27 11.1 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 PSC71846.1 - 0.0013 19.2 1.7 0.0036 17.7 0.0 2.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 PSC71846.1 - 0.0014 18.9 0.0 0.003 17.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain T2SSE PF00437.20 PSC71846.1 - 0.0015 17.7 0.2 0.0034 16.5 0.0 1.6 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_18 PF13238.6 PSC71846.1 - 0.0096 16.5 0.0 0.25 11.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain MeaB PF03308.16 PSC71846.1 - 0.012 14.6 0.3 0.39 9.6 0.0 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 PSC71846.1 - 0.014 15.0 0.1 2.2 7.8 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.6 PSC71846.1 - 0.015 15.4 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 PSC71846.1 - 0.019 14.9 0.0 0.033 14.1 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 PSC71846.1 - 0.026 14.8 0.6 0.083 13.1 0.0 2.2 3 0 0 3 3 2 0 AAA domain AAA_33 PF13671.6 PSC71846.1 - 0.031 14.4 1.5 0.043 14.0 0.2 2.2 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.6 PSC71846.1 - 0.044 14.3 0.1 0.078 13.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PSC71846.1 - 0.057 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_24 PF13479.6 PSC71846.1 - 0.059 13.1 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 PSC71846.1 - 0.1 12.6 0.0 0.34 10.9 0.0 1.8 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRPRB PF09439.10 PSC71846.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 PSC71846.1 - 0.12 12.9 0.1 0.41 11.2 0.1 1.7 1 1 0 1 1 1 0 ABC transporter MMR_HSR1 PF01926.23 PSC71846.1 - 0.15 12.1 0.5 0.61 10.2 0.4 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase dNK PF01712.19 PSC71846.1 - 0.19 11.5 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Deoxynucleoside kinase Zip PF02535.22 PSC71846.1 - 3.6 6.7 14.7 5.6 6.1 14.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Glyco_transf_49 PF13896.6 PSC71847.1 - 1.3e-33 116.8 2.9 4.1e-32 111.8 2.9 2.5 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Ank_2 PF12796.7 PSC71847.1 - 1.8e-11 44.4 0.8 0.0075 16.8 0.1 5.6 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC71847.1 - 6.9e-07 29.7 0.9 0.37 11.4 0.0 5.5 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC71847.1 - 7.5e-06 25.9 0.3 3.2 8.6 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 PSC71847.1 - 0.00063 20.0 0.0 1.9 8.9 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 PSC71847.1 - 0.063 13.8 6.2 12 6.5 0.0 5.5 6 0 0 6 6 6 0 Ankyrin repeat Glyco_transf_49 PF13896.6 PSC71848.1 - 1.3e-33 116.8 2.9 4.1e-32 111.8 2.9 2.5 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Ank_2 PF12796.7 PSC71848.1 - 1.8e-11 44.5 0.8 0.0074 16.8 0.1 5.6 4 1 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC71848.1 - 6.9e-07 29.7 0.9 0.37 11.4 0.0 5.5 3 1 3 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC71848.1 - 7.5e-06 25.9 0.3 3.2 8.6 0.0 5.6 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.6 PSC71848.1 - 0.00062 20.0 0.0 1.9 8.9 0.0 4.6 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Ank PF00023.30 PSC71848.1 - 0.063 13.8 6.2 12 6.5 0.0 5.5 6 0 0 6 6 6 0 Ankyrin repeat YobH PF13996.6 PSC71850.1 - 0.07 13.2 0.3 0.18 11.9 0.3 1.7 1 0 0 1 1 1 0 YobH-like protein GCP_C_terminal PF04130.13 PSC71851.1 - 5.3e-32 111.5 0.0 5.4e-29 101.6 0.0 3.2 3 0 0 3 3 3 2 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 PSC71851.1 - 5.5e-09 36.1 0.0 5.9e-08 32.7 0.0 2.4 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal CSTF1_dimer PF16699.5 PSC71851.1 - 0.14 11.9 4.1 14 5.5 0.0 3.8 3 0 0 3 3 3 0 Cleavage stimulation factor subunit 1, dimerisation domain IPP-2 PF04979.14 PSC71852.1 - 5.6e-18 66.0 14.9 1.6e-16 61.2 14.9 2.1 1 1 0 1 1 1 1 Protein phosphatase inhibitor 2 (IPP-2) Hemerythrin PF01814.23 PSC71852.1 - 0.18 12.4 6.1 0.065 13.9 3.0 1.9 2 1 0 2 2 2 0 Hemerythrin HHE cation binding domain PGA2 PF07543.12 PSC71852.1 - 7.3 6.6 11.1 0.11 12.5 2.4 2.2 2 1 0 2 2 2 0 Protein trafficking PGA2 FAM176 PF14851.6 PSC71852.1 - 8.8 6.0 7.4 0.37 10.4 1.1 1.9 2 1 0 2 2 2 0 FAM176 family SMC_N PF02463.19 PSC71853.1 - 1.3e-21 77.1 0.0 2.1e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 PSC71853.1 - 1e-16 62.0 12.2 1e-16 62.0 12.2 4.6 2 2 0 2 2 1 1 AAA domain AAA_21 PF13304.6 PSC71853.1 - 5.1e-07 29.8 0.0 0.016 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PSC71853.1 - 2.1e-05 24.5 0.0 0.00012 21.9 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 PSC71853.1 - 6.7e-05 22.6 0.0 0.00014 21.5 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain CREPT PF16566.5 PSC71853.1 - 0.0061 16.7 1.8 0.0061 16.7 1.8 5.1 4 1 0 4 4 3 2 Cell-cycle alteration and expression-elevated protein in tumour AAA_16 PF13191.6 PSC71853.1 - 0.11 12.9 0.0 0.11 12.9 0.0 4.7 3 2 0 3 3 1 0 AAA ATPase domain AAA_27 PF13514.6 PSC71853.1 - 0.2 11.2 0.0 0.2 11.2 0.0 4.7 5 1 0 5 5 5 0 AAA domain RSS_P20 PF11757.8 PSC71853.1 - 0.97 9.9 6.2 3.3 8.2 0.2 3.9 2 1 1 3 3 3 0 Suppressor of RNA silencing P21-like N-terminal domain DUF2730 PF10805.8 PSC71853.1 - 2.9 8.0 21.3 0.16 12.1 0.2 5.5 5 1 1 6 6 6 0 Protein of unknown function (DUF2730) DASH_Dad3 PF08656.10 PSC71853.1 - 6.3 7.0 8.4 0.44 10.7 0.6 3.1 3 0 0 3 3 3 0 DASH complex subunit Dad3 L71 PF02448.15 PSC71853.1 - 7.4 7.1 9.7 0.54 10.7 2.9 2.6 3 0 0 3 3 3 0 L71 family HydF_tetramer PF18133.1 PSC71854.1 - 2.1e-37 127.5 0.1 9.4e-37 125.4 0.0 2.1 2 0 0 2 2 2 1 Hydrogen maturase F tetramerization domain Radical_SAM PF04055.21 PSC71854.1 - 1.3e-17 64.7 0.0 2.5e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily MMR_HSR1 PF01926.23 PSC71854.1 - 5e-17 62.0 0.0 1.1e-16 60.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PSC71854.1 - 7.6e-06 25.5 0.2 3.6e-05 23.3 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B HydF_dimer PF18128.1 PSC71854.1 - 0.00033 20.7 0.0 0.067 13.3 0.0 2.7 1 1 0 1 1 1 1 Hydrogen maturase F dimerization domain Dynamin_N PF00350.23 PSC71854.1 - 0.00046 20.3 0.1 0.001 19.2 0.1 1.5 1 1 0 1 1 1 1 Dynamin family CMD PF02627.20 PSC71854.1 - 0.046 13.8 2.0 0.19 11.8 0.0 3.1 3 0 0 3 3 3 0 Carboxymuconolactone decarboxylase family Ras PF00071.22 PSC71854.1 - 0.17 11.5 0.0 0.31 10.6 0.0 1.3 1 0 0 1 1 1 0 Ras family GTP_EFTU PF00009.27 PSC71854.1 - 0.44 10.1 1.0 2.6 7.5 1.0 2.0 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain B-block_TFIIIC PF04182.12 PSC71855.1 - 8.3e-12 45.1 0.0 1.7e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 B-block binding subunit of TFIIIC HTH_27 PF13463.6 PSC71855.1 - 0.059 13.9 0.0 0.22 12.1 0.0 2.0 1 0 0 1 1 1 0 Winged helix DNA-binding domain Lipase_3 PF01764.25 PSC71856.1 - 0.0055 16.6 0.1 0.0055 16.6 0.1 1.6 2 0 0 2 2 2 1 Lipase (class 3) adh_short PF00106.25 PSC71857.1 - 3.1e-22 79.0 1.8 4.5e-10 39.3 0.5 3.2 2 1 1 3 3 3 3 short chain dehydrogenase adh_short_C2 PF13561.6 PSC71857.1 - 2.1e-09 37.3 6.6 0.0003 20.4 0.1 3.7 2 1 1 3 3 3 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC71857.1 - 4.2e-05 23.5 0.8 7.9e-05 22.6 0.5 1.5 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 PSC71857.1 - 0.021 14.3 0.4 1.6 8.2 0.1 2.2 1 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family p25-alpha PF05517.12 PSC71858.1 - 1.5e-49 168.2 0.0 4.2e-27 95.2 0.0 2.4 2 0 0 2 2 2 2 p25-alpha EF-hand_6 PF13405.6 PSC71858.1 - 3.4e-07 29.6 0.1 0.00014 21.5 0.0 3.6 4 0 0 4 4 4 1 EF-hand domain EF-hand_1 PF00036.32 PSC71858.1 - 5.7e-07 28.6 0.0 7.4e-05 22.0 0.0 3.5 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 PSC71858.1 - 0.00041 20.8 0.0 0.0023 18.4 0.0 2.2 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 PSC71858.1 - 0.0013 18.1 0.0 0.034 13.7 0.0 2.5 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 PSC71858.1 - 0.2 11.5 0.3 6 6.8 0.0 3.2 4 1 0 4 4 4 0 EF-hand domain pair RuBisCO_large_N PF02788.16 PSC71858.1 - 0.24 11.6 4.2 0.48 10.6 4.2 1.4 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain FAM117 PF15388.6 PSC71859.1 - 0.018 14.5 0.0 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein Family FAM117 ALF PF03752.13 PSC71859.1 - 0.022 14.7 1.2 2.8 8.0 0.3 2.6 2 0 0 2 2 2 0 Short repeats of unknown function Tn7_Tnp_TnsA_C PF08721.11 PSC71859.1 - 0.074 13.7 0.2 0.1 13.2 0.2 1.3 1 1 0 1 1 1 0 TnsA endonuclease C terminal LRR_8 PF13855.6 PSC71860.1 - 0.71 9.7 9.8 0.25 11.1 0.4 3.9 4 1 1 5 5 5 0 Leucine rich repeat Ank_2 PF12796.7 PSC71861.1 - 0.00012 22.6 0.0 0.00027 21.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PSC71861.1 - 0.0014 18.9 0.0 2.3 9.1 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.6 PSC71861.1 - 0.0015 19.0 0.0 0.1 13.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 PSC71861.1 - 0.0043 17.4 0.0 1.8 9.1 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 PSC71861.1 - 0.0057 16.9 0.0 0.014 15.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Asp-B-Hydro_N PF05279.11 PSC71861.1 - 5.6 7.0 15.7 8.1 6.4 15.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Macoilin PF09726.9 PSC71861.1 - 6.8 5.1 20.8 13 4.2 20.8 1.5 1 1 0 1 1 1 0 Macoilin family DIE2_ALG10 PF04922.12 PSC71862.1 - 1.4e-110 370.3 0.0 1.6e-110 370.1 0.0 1.0 1 0 0 1 1 1 1 DIE2/ALG10 family TK PF00265.18 PSC71863.1 - 4.8e-51 173.1 0.0 5.9e-51 172.8 0.0 1.1 1 0 0 1 1 1 1 Thymidine kinase PsbQ PF05757.11 PSC71863.1 - 0.87 9.3 6.1 1.8 8.2 6.1 1.5 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) TFIIA PF03153.13 PSC71863.1 - 1 9.3 5.1 1.4 8.8 5.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DEAD PF00270.29 PSC71864.1 - 1.3e-50 171.6 0.0 1.8e-50 171.1 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC71864.1 - 2.8e-34 117.8 0.0 9.7e-32 109.6 0.0 2.2 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 PSC71864.1 - 0.0055 16.7 0.0 0.0084 16.1 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 PSC71864.1 - 0.07 12.3 0.0 0.24 10.6 0.0 1.7 2 0 0 2 2 2 0 ERCC3/RAD25/XPB C-terminal helicase Ribosomal_L17 PF01196.19 PSC71865.1 - 1.8e-29 102.5 0.0 3e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L17 CPBP PF02517.16 PSC71865.1 - 7.8e-15 55.0 2.9 9.9e-15 54.7 1.5 1.8 2 0 0 2 2 2 1 CPBP intramembrane metalloprotease FAP PF07174.11 PSC71865.1 - 2.6 7.4 22.5 6.1 6.2 22.5 1.5 1 1 0 1 1 1 0 Fibronectin-attachment protein (FAP) TFIIA PF03153.13 PSC71865.1 - 5.1 7.0 10.0 6.9 6.6 10.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CTP_transf_like PF01467.26 PSC71866.1 - 8.8e-39 133.0 0.0 6e-22 78.4 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 PSC71866.1 - 4.4e-05 23.4 0.3 0.25 11.2 0.2 3.0 3 0 0 3 3 3 2 FAD synthetase EnY2 PF10163.9 PSC71867.1 - 7.8e-17 61.4 0.1 7.8e-17 61.4 0.1 1.7 2 0 0 2 2 2 1 Transcription factor e(y)2 B3 PF02362.21 PSC71867.1 - 1.7e-06 27.8 0.0 3e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 B3 DNA binding domain DUF1980 PF09323.10 PSC71867.1 - 0.14 12.1 4.6 0.24 11.3 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) FHIPEP PF00771.20 PSC71867.1 - 1.1 7.6 3.7 56 2.0 0.0 2.1 2 0 0 2 2 2 0 FHIPEP family PAT1 PF09770.9 PSC71867.1 - 3.4 5.8 29.8 5.1 5.2 29.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF179 PF02622.15 PSC71868.1 - 2.9e-27 95.6 0.0 5.6e-27 94.7 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 SMP PF04927.12 PSC71868.1 - 0.047 14.2 1.3 0.047 14.2 1.3 2.3 3 0 0 3 3 3 0 Seed maturation protein Baculo_PEP_C PF04513.12 PSC71869.1 - 0.00027 21.0 0.4 0.00038 20.5 0.4 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3606 PF12244.8 PSC71869.1 - 0.022 14.7 0.8 0.12 12.3 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3606) Flp_Fap PF04964.14 PSC71869.1 - 0.044 13.6 0.3 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Flp/Fap pilin component SIS PF01380.22 PSC71870.1 - 2.6e-20 72.6 0.0 3.9e-20 72.0 0.0 1.3 1 0 0 1 1 1 1 SIS domain CBS PF00571.28 PSC71870.1 - 1.8e-14 53.9 2.1 1.2e-06 28.8 0.0 2.6 3 0 0 3 3 3 2 CBS domain SIS_2 PF13580.6 PSC71870.1 - 2.7e-05 24.2 0.0 0.0061 16.6 0.0 2.5 1 1 1 2 2 2 2 SIS domain BPL_N PF09825.9 PSC71871.1 - 1.4e-56 192.2 2.9 2.1e-56 191.6 2.9 1.1 1 0 0 1 1 1 1 Biotin-protein ligase, N terminal PAP2 PF01569.21 PSC71871.1 - 2.8e-07 30.4 13.9 5.8e-07 29.4 10.2 2.9 2 1 0 2 2 2 1 PAP2 superfamily Sporozoite_P67 PF05642.11 PSC71871.1 - 4.4 5.3 7.9 6.1 4.8 7.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen CBM_20 PF00686.19 PSC71872.1 - 2e-15 56.4 0.0 4.1e-15 55.5 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain Bcl-2_BAD PF10514.9 PSC71872.1 - 0.023 15.2 1.6 0.023 15.2 1.6 1.5 2 0 0 2 2 2 0 Pro-apoptotic Bcl-2 protein, BAD Metallophos PF00149.28 PSC71873.1 - 5.2e-09 36.9 1.1 6.9e-09 36.5 1.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PSC71873.1 - 0.0091 16.2 0.3 0.025 14.8 0.0 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Aminotran_5 PF00266.19 PSC71875.1 - 2.1e-20 73.0 0.0 2.5e-20 72.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 PSC71875.1 - 0.015 13.9 0.0 0.019 13.5 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DegT_DnrJ_EryC1 PF01041.17 PSC71875.1 - 0.023 14.0 0.1 0.032 13.6 0.1 1.1 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Beta_elim_lyase PF01212.21 PSC71875.1 - 0.04 13.2 0.0 0.049 12.9 0.0 1.1 1 0 0 1 1 1 0 Beta-eliminating lyase polyprenyl_synt PF00348.17 PSC71876.1 - 1.2e-69 234.2 0.0 1.6e-69 233.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase COPIIcoated_ERV PF07970.12 PSC71879.1 - 1.1e-85 287.0 0.3 1.5e-85 286.6 0.3 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 PSC71879.1 - 3.8e-28 97.7 0.0 8.1e-28 96.6 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Molybdopterin PF00384.22 PSC71880.1 - 6.5e-62 209.9 0.0 3.7e-61 207.4 0.0 2.0 1 1 0 1 1 1 1 Molybdopterin oxidoreductase SKI PF01202.22 PSC71880.1 - 3.3e-41 141.0 0.0 9.3e-41 139.6 0.0 1.8 2 0 0 2 2 1 1 Shikimate kinase Fer2_4 PF13510.6 PSC71880.1 - 5.1e-21 74.5 0.1 1.3e-20 73.2 0.1 1.8 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 PSC71880.1 - 5.7e-16 57.8 0.1 1.2e-15 56.7 0.1 1.6 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region NADH_dhqG_C PF09326.11 PSC71880.1 - 1.5e-09 38.4 0.0 4.7e-09 36.8 0.0 2.0 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit G, C-terminal Fer2 PF00111.27 PSC71880.1 - 6.9e-09 35.5 0.2 6.9e-09 35.5 0.2 1.9 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain AAA_33 PF13671.6 PSC71880.1 - 8e-06 26.1 2.1 5.2e-05 23.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 PSC71880.1 - 1.5e-05 25.6 0.0 3.8e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 PSC71880.1 - 0.00014 22.1 0.2 0.00087 19.5 0.0 2.3 2 0 0 2 2 2 1 Cytidylate kinase-like family Cytidylate_kin PF02224.18 PSC71880.1 - 0.0033 17.2 0.3 0.012 15.4 0.0 2.0 2 0 0 2 2 2 1 Cytidylate kinase RsgA_GTPase PF03193.16 PSC71880.1 - 0.011 15.6 0.0 0.046 13.6 0.0 1.9 2 0 0 2 2 2 0 RsgA GTPase XdhC_C PF13478.6 PSC71880.1 - 0.014 15.9 2.0 0.13 12.8 0.2 3.1 3 0 0 3 3 3 0 XdhC Rossmann domain AAA_16 PF13191.6 PSC71880.1 - 0.02 15.3 0.0 0.088 13.2 0.0 2.3 1 0 0 1 1 1 0 AAA ATPase domain CoaE PF01121.20 PSC71880.1 - 0.11 12.1 0.0 0.27 10.9 0.0 1.5 1 0 0 1 1 1 0 Dephospho-CoA kinase AAA_17 PF13207.6 PSC71880.1 - 0.14 12.6 0.0 0.37 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain Rieske_2 PF13806.6 PSC71881.1 - 3.9e-17 62.1 0.0 6.1e-17 61.5 0.0 1.3 1 0 0 1 1 1 1 Rieske-like [2Fe-2S] domain Polysacc_deac_1 PF01522.21 PSC71882.1 - 8.5e-09 35.4 0.0 1.6e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Trypan_PARP PF05887.11 PSC71882.1 - 0.024 14.6 17.1 0.045 13.7 17.1 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF3119 PF11317.8 PSC71883.1 - 1.8e-44 151.1 0.2 2.2e-44 150.8 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3119) DUF4520 PF15016.6 PSC71883.1 - 0.086 12.9 0.1 0.14 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4520) Vps16_N PF04841.13 PSC71884.1 - 1.1e-52 179.2 0.0 1.7e-52 178.6 0.0 1.2 1 0 0 1 1 1 1 Vps16, N-terminal region Vps16_C PF04840.12 PSC71884.1 - 8.8e-37 126.8 0.0 1.5e-19 70.2 0.0 2.1 2 0 0 2 2 2 2 Vps16, C-terminal region TPR_7 PF13176.6 PSC71884.1 - 2.2 8.5 4.6 32 4.9 0.8 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RPE65 PF03055.15 PSC71885.1 - 1.5e-82 278.3 0.0 1.7e-82 278.1 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein YgbB PF02542.16 PSC71886.1 - 2.4e-64 216.3 0.0 2.9e-64 216.0 0.0 1.1 1 0 0 1 1 1 1 YgbB family Rhodanese PF00581.20 PSC71887.1 - 4.8e-12 46.3 0.0 5.6e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Rhodanese-like domain Vps16_N PF04841.13 PSC71888.1 - 0.0009 18.1 0.0 0.0013 17.6 0.0 1.3 1 1 0 1 1 1 1 Vps16, N-terminal region Flavin_Reduct PF01613.18 PSC71889.1 - 1.3e-21 77.3 0.1 1.8e-21 76.8 0.1 1.2 1 0 0 1 1 1 1 Flavin reductase like domain AMP-binding PF00501.28 PSC71890.1 - 1.1e-77 261.4 0.0 1.4e-77 261.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PSC71890.1 - 7.6e-20 71.7 0.0 1.8e-19 70.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RRM_1 PF00076.22 PSC71891.1 - 6.9e-12 45.0 0.0 4.7e-07 29.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SPOC PF07744.13 PSC71891.1 - 8.7e-12 45.2 0.0 1.7e-11 44.2 0.0 1.4 1 0 0 1 1 1 1 SPOC domain API5 PF05918.11 PSC71891.1 - 0.0026 16.6 0.0 0.0026 16.6 0.0 2.5 3 0 0 3 3 3 2 Apoptosis inhibitory protein 5 (API5) CcmD PF04995.14 PSC71892.1 - 0.00063 19.8 0.2 0.00091 19.3 0.2 1.2 1 0 0 1 1 1 1 Heme exporter protein D (CcmD) RskA PF10099.9 PSC71892.1 - 0.011 16.1 1.3 0.011 16.0 1.3 1.0 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Sensor PF13796.6 PSC71892.1 - 0.014 15.4 0.3 0.014 15.4 0.3 1.0 1 0 0 1 1 1 0 Putative sensor OSTbeta PF15048.6 PSC71892.1 - 0.037 14.2 0.0 0.044 13.9 0.0 1.1 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein EphA2_TM PF14575.6 PSC71892.1 - 0.1 13.5 0.0 0.11 13.4 0.0 1.1 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain VSP PF03302.13 PSC71892.1 - 0.55 9.0 5.6 0.66 8.8 5.6 1.1 1 0 0 1 1 1 0 Giardia variant-specific surface protein CYYR1 PF10873.8 PSC71892.1 - 4.7 7.7 5.4 2.5 8.5 4.1 1.3 1 1 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 DUF2613 PF11021.8 PSC71892.1 - 9.5 6.4 10.1 15 5.8 9.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2613) DEC-1_N PF04625.13 PSC71893.1 - 1.4 7.9 9.3 2 7.4 9.3 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Nucleotid_trans PF03407.16 PSC71894.1 - 1.2e-34 120.2 0.4 3e-34 118.9 0.4 1.5 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase HemS PF05171.12 PSC71894.1 - 0.14 12.1 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Haemin-degrading HemS.ChuX domain ChuX_HutX PF06228.13 PSC71894.1 - 0.18 11.5 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Haem utilisation ChuX/HutX SecE PF00584.20 PSC71896.1 - 6.7e-13 48.3 0.2 7.5e-13 48.2 0.2 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex NHR2 PF08788.11 PSC71896.1 - 0.023 14.5 0.0 0.028 14.2 0.0 1.1 1 0 0 1 1 1 0 NHR2 domain like GLE1 PF07817.13 PSC71897.1 - 1.7e-51 174.8 0.2 1.7e-51 174.8 0.2 1.8 2 0 0 2 2 2 1 GLE1-like protein DUF966 PF06136.13 PSC71897.1 - 2.7 7.7 12.3 3.9 7.1 12.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF966) V_ATPase_I PF01496.19 PSC71897.1 - 4.5 5.1 9.4 5.7 4.7 9.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family LRR_8 PF13855.6 PSC71898.1 - 1.1e-08 34.7 0.0 5e-06 26.2 0.0 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 PSC71898.1 - 0.00014 21.9 0.0 10 7.1 0.0 4.1 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_4 PF12799.7 PSC71898.1 - 0.0003 21.1 0.0 0.12 12.8 0.0 2.5 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) Glug PF07581.12 PSC71898.1 - 0.35 11.4 4.5 11 6.7 0.0 3.3 3 0 0 3 3 3 0 The GLUG motif Fe-S_biosyn PF01521.20 PSC71899.1 - 6.7e-22 77.8 0.0 8.2e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Thioredoxin_4 PF13462.6 PSC71900.1 - 0.63 10.2 3.3 1.7 8.8 3.3 1.7 1 0 0 1 1 1 0 Thioredoxin SMC_N PF02463.19 PSC71901.1 - 8.3e-21 74.4 0.0 1.1e-20 74.0 0.0 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 PSC71901.1 - 3.2e-09 37.6 11.9 3.2e-09 37.6 11.9 3.6 2 2 0 2 2 2 1 AAA domain AAA_29 PF13555.6 PSC71901.1 - 3.6e-05 23.4 0.1 8e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 PSC71901.1 - 0.0043 16.9 0.2 0.0085 15.9 0.2 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PSC71901.1 - 0.006 16.3 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 PSC71901.1 - 0.056 14.0 1.3 0.87 10.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 PSC71901.1 - 0.49 10.9 0.0 0.49 10.9 0.0 3.9 4 2 0 4 4 4 0 ABC transporter DUF948 PF06103.11 PSC71901.1 - 8.1 6.8 17.5 3.4 8.0 0.1 4.3 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) Autophagy_act_C PF03987.15 PSC71902.1 - 4.1e-14 52.9 0.0 7.2e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain CNDH2_M PF16869.5 PSC71902.1 - 0.016 15.9 0.1 0.035 14.8 0.0 1.6 2 0 0 2 2 2 0 PF16858 DinB_2 PF12867.7 PSC71902.1 - 6.6 7.3 8.9 28 5.2 8.9 2.2 1 1 0 1 1 1 0 DinB superfamily Lipase_3 PF01764.25 PSC71903.1 - 0.00074 19.4 0.0 0.0014 18.5 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Presenilin PF01080.17 PSC71903.1 - 0.085 11.6 2.9 0.12 11.1 2.9 1.2 1 0 0 1 1 1 0 Presenilin VIT1 PF01988.19 PSC71903.1 - 0.13 12.1 2.8 0.23 11.3 2.8 1.4 1 0 0 1 1 1 0 VIT family Atrophin-1 PF03154.15 PSC71903.1 - 2.3 6.4 21.6 3.5 5.8 21.6 1.2 1 0 0 1 1 1 0 Atrophin-1 family DUF4407 PF14362.6 PSC71903.1 - 2.4 7.4 13.5 3.6 6.8 13.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 PSC71903.1 - 3.6 7.5 9.0 4.8 7.1 9.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RRM_1 PF00076.22 PSC71904.1 - 1.6e-29 101.5 0.4 2.8e-15 55.9 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PSC71904.1 - 6.8e-05 22.8 1.5 0.15 12.1 0.1 2.2 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 PSC71904.1 - 9.8e-05 22.3 0.6 0.015 15.3 0.1 2.3 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif DbpA PF03880.15 PSC71904.1 - 0.00021 21.2 0.4 0.0045 16.9 0.2 2.2 2 0 0 2 2 2 1 DbpA RNA binding domain RRM_5 PF13893.6 PSC71904.1 - 0.002 17.7 0.0 0.65 9.6 0.0 2.1 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 PSC71904.1 - 0.0094 16.0 0.0 0.14 12.2 0.0 2.1 2 0 0 2 2 2 1 RNA binding domain RRM_7 PF16367.5 PSC71904.1 - 0.047 13.8 0.0 7.4 6.8 0.0 2.5 2 0 0 2 2 2 0 RNA recognition motif Limkain-b1 PF11608.8 PSC71904.1 - 0.083 13.0 1.3 0.28 11.3 0.1 2.1 2 0 0 2 2 2 0 Limkain b1 PHM7_cyt PF14703.6 PSC71904.1 - 0.17 12.1 0.1 19 5.5 0.0 2.2 2 0 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter GHMP_kinases_C PF08544.13 PSC71904.1 - 1.8 9.0 0.0 1.8 9.0 0.0 2.9 3 0 0 3 3 3 0 GHMP kinases C terminal Ribosomal_S30AE PF02482.19 PSC71905.1 - 3.5e-23 82.2 1.4 6.3e-23 81.4 1.4 1.4 1 0 0 1 1 1 1 Sigma 54 modulation protein / S30EA ribosomal protein Ribosom_S30AE_C PF16321.5 PSC71905.1 - 1.7e-17 62.8 0.1 3.9e-17 61.7 0.1 1.6 1 0 0 1 1 1 1 Sigma 54 modulation/S30EA ribosomal protein C terminus tRNA_int_endo PF01974.17 PSC71906.1 - 1.7e-17 63.3 0.0 2.9e-17 62.5 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo PF01974.17 PSC71907.1 - 1.5e-17 63.4 0.0 2.7e-17 62.6 0.0 1.3 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain bZIP_1 PF00170.21 PSC71908.1 - 0.007 16.4 6.9 0.016 15.3 6.9 1.6 1 0 0 1 1 1 1 bZIP transcription factor CASP_C PF08172.12 PSC71908.1 - 0.0078 15.6 0.4 0.012 15.0 0.4 1.2 1 0 0 1 1 1 1 CASP C terminal SNAPc19 PF15497.6 PSC71908.1 - 0.076 13.5 2.0 0.16 12.4 2.0 1.5 1 0 0 1 1 1 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 DUF4665 PF15679.5 PSC71908.1 - 0.18 12.5 2.0 0.31 11.7 2.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) Cnn_1N PF07989.11 PSC71908.1 - 0.28 11.4 3.8 0.58 10.3 3.8 1.5 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 YabA PF06156.13 PSC71908.1 - 0.39 11.4 2.6 0.82 10.3 2.6 1.4 1 0 0 1 1 1 0 Initiation control protein YabA FlaC_arch PF05377.11 PSC71908.1 - 1.1 9.7 3.4 2.1 8.8 3.4 1.4 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) CENP-H PF05837.12 PSC71908.1 - 1.2 9.6 11.5 0.22 12.0 6.9 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) bZIP_2 PF07716.15 PSC71908.1 - 1.3 9.2 6.9 5.1 7.2 6.9 2.0 1 1 0 1 1 1 0 Basic region leucine zipper HSCB_C PF07743.13 PSC71908.1 - 8.3 7.0 10.2 9.8 6.8 0.1 3.7 3 1 0 3 3 3 0 HSCB C-terminal oligomerisation domain Methyltransf_11 PF08241.12 PSC71909.1 - 0.00068 20.2 0.1 0.0013 19.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC71909.1 - 0.0015 18.4 0.0 0.0025 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC71909.1 - 0.0093 16.7 0.0 0.019 15.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC71909.1 - 0.1 13.3 0.1 0.19 12.5 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain RPE65 PF03055.15 PSC71910.1 - 1.4e-77 261.8 0.0 2.4e-77 261.1 0.0 1.2 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein DUF563 PF04577.14 PSC71910.1 - 0.023 14.8 0.0 0.051 13.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF563) Peptidase_M48 PF01435.18 PSC71911.1 - 2e-19 70.1 0.2 1.7e-17 63.9 0.2 2.1 1 1 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 PSC71911.1 - 0.01 15.1 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 1 BlaR1 peptidase M56 WD40 PF00400.32 PSC71912.1 - 3.4e-15 56.2 11.4 0.00016 22.4 0.1 6.8 7 0 0 7 7 7 3 WD domain, G-beta repeat Response_reg PF00072.24 PSC71912.1 - 9.6e-06 25.7 0.0 2.1e-05 24.7 0.0 1.6 1 0 0 1 1 1 1 Response regulator receiver domain Pkinase PF00069.25 PSC71912.1 - 2.6e-05 23.7 0.0 4.1e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40_like PF17005.5 PSC71912.1 - 0.053 12.8 0.0 0.14 11.4 0.0 1.6 2 0 0 2 2 2 0 WD40-like domain HVSL PF09749.9 PSC71913.1 - 2.7e-40 138.3 0.0 4.5e-40 137.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised conserved protein 2OG-FeII_Oxy_3 PF13640.6 PSC71913.1 - 4.2e-06 27.6 0.1 1.1e-05 26.2 0.1 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 PSC71913.1 - 0.00013 22.6 0.1 0.00024 21.7 0.1 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2_5_RNA_ligase2 PF13563.6 PSC71913.1 - 0.0021 18.0 0.2 0.11 12.4 0.1 2.9 3 0 0 3 3 3 1 2'-5' RNA ligase superfamily ABC_tran PF00005.27 PSC71914.1 - 6.6e-19 68.8 0.0 1.3e-18 67.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane_2 PF06472.15 PSC71914.1 - 2.4e-16 59.9 0.5 3.6e-16 59.4 0.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 SbmA_BacA PF05992.12 PSC71914.1 - 1.9e-05 24.3 0.0 2.7e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 SbmA/BacA-like family AAA_30 PF13604.6 PSC71914.1 - 8.2e-05 22.4 0.1 0.054 13.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 PSC71914.1 - 0.0024 18.3 1.8 0.0024 18.3 1.8 2.3 2 1 0 2 2 2 1 AAA ATPase domain NINJA_B PF16136.5 PSC71914.1 - 0.016 15.6 1.1 0.045 14.1 1.1 1.8 1 0 0 1 1 1 0 Putative nuclear localisation signal ABC_membrane PF00664.23 PSC71914.1 - 0.019 14.6 0.1 0.027 14.1 0.1 1.1 1 0 0 1 1 1 0 ABC transporter transmembrane region SMC_N PF02463.19 PSC71914.1 - 0.023 14.1 0.1 1.8 7.9 0.0 2.4 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 PSC71914.1 - 0.047 14.0 0.1 0.17 12.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 PSC71914.1 - 0.076 12.7 0.1 0.62 9.7 0.0 2.2 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_29 PF13555.6 PSC71914.1 - 0.078 12.7 0.1 0.24 11.2 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_21 PF13304.6 PSC71914.1 - 0.11 12.2 0.1 0.48 10.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 PSC71914.1 - 0.13 12.1 0.2 0.25 11.2 0.2 1.3 1 0 0 1 1 1 0 RsgA GTPase NACHT PF05729.12 PSC71914.1 - 0.21 11.5 0.1 0.34 10.8 0.1 1.3 1 0 0 1 1 1 0 NACHT domain AAA PF00004.29 PSC71914.1 - 0.22 12.0 0.0 0.64 10.5 0.1 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 PSC71914.1 - 0.24 11.9 0.2 0.52 10.8 0.1 1.5 2 0 0 2 2 1 0 AAA domain AF-4 PF05110.13 PSC71914.1 - 0.49 8.4 4.3 0.66 8.0 4.3 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein SR-25 PF10500.9 PSC71914.1 - 0.63 9.6 6.4 0.98 9.0 6.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein IMUP PF15761.5 PSC71914.1 - 4.3 8.1 14.2 12 6.6 14.2 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein Curlin_rpt PF07012.12 PSC71915.1 - 5.1 7.2 21.4 0.14 12.2 6.5 3.0 2 1 1 3 3 3 0 Curlin associated repeat Fasciclin PF02469.22 PSC71916.1 - 5e-19 68.8 0.1 7.8e-18 64.9 0.1 2.1 1 1 0 1 1 1 1 Fasciclin domain Na_Ca_ex PF01699.24 PSC71917.1 - 5.6e-37 127.0 42.0 1.7e-19 70.3 19.4 2.2 2 0 0 2 2 2 2 Sodium/calcium exchanger protein RPE65 PF03055.15 PSC71918.1 - 3.7e-86 290.2 0.0 5.2e-86 289.7 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein rve PF00665.26 PSC71918.1 - 4.6e-17 62.3 0.3 1.6e-16 60.6 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 PSC71918.1 - 0.0097 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain RPE65 PF03055.15 PSC71919.1 - 3.7e-86 290.1 0.0 5.3e-86 289.6 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein rve PF00665.26 PSC71919.1 - 4.7e-17 62.3 0.3 1.6e-16 60.5 0.0 2.1 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 PSC71919.1 - 0.0095 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain BATS PF06968.13 PSC71920.1 - 4e-25 87.8 0.0 1.1e-24 86.3 0.0 1.8 1 0 0 1 1 1 1 Biotin and Thiamin Synthesis associated domain Radical_SAM PF04055.21 PSC71920.1 - 4.7e-07 30.3 0.0 1.8e-06 28.5 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Fer4_12 PF13353.6 PSC71920.1 - 0.041 14.2 0.0 0.077 13.3 0.0 1.4 1 0 0 1 1 1 0 4Fe-4S single cluster domain Sigma70_r4_2 PF08281.12 PSC71920.1 - 0.1 12.3 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 Sigma-70, region 4 UQ_con PF00179.26 PSC71921.1 - 6.3e-54 181.4 0.0 7e-54 181.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 PSC71921.1 - 0.00039 20.7 0.0 0.00055 20.2 0.0 1.4 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 PSC71921.1 - 0.00063 19.5 0.0 0.00068 19.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 PSC71921.1 - 0.02 14.7 0.1 0.032 14.1 0.1 1.3 1 0 0 1 1 1 0 UEV domain AAA_12 PF13087.6 PSC71922.1 - 7.9e-51 172.5 0.0 1.2e-50 172.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain Dna2 PF08696.11 PSC71922.1 - 6.9e-47 159.9 0.0 9.6e-47 159.4 0.0 1.2 1 0 0 1 1 1 1 DNA replication factor Dna2 AAA_11 PF13086.6 PSC71922.1 - 1.4e-29 103.7 0.0 2.1e-14 53.9 0.0 2.8 3 0 0 3 3 3 2 AAA domain AAA_30 PF13604.6 PSC71922.1 - 6.1e-12 45.7 0.1 6.1e-12 45.7 0.1 3.2 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.6 PSC71922.1 - 5.1e-10 39.8 0.0 2.9e-09 37.4 0.0 2.3 3 0 0 3 3 2 1 AAA domain Viral_helicase1 PF01443.18 PSC71922.1 - 9.4e-08 32.1 0.0 0.1 12.3 0.0 3.3 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase Cas_Cas4 PF01930.17 PSC71922.1 - 2.8e-05 24.3 0.0 6.3e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF83 UvrD-helicase PF00580.21 PSC71922.1 - 0.00027 20.6 0.0 0.00046 19.8 0.0 1.3 1 0 0 1 1 1 1 UvrD/REP helicase N-terminal domain SRP54 PF00448.22 PSC71922.1 - 0.0007 19.3 0.0 0.0027 17.3 0.1 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain UvrD_C_2 PF13538.6 PSC71922.1 - 0.0031 17.3 0.0 0.0074 16.1 0.0 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Helicase_RecD PF05127.14 PSC71922.1 - 0.016 15.0 0.0 0.041 13.7 0.0 1.7 1 0 0 1 1 1 0 Helicase NTPase_1 PF03266.15 PSC71922.1 - 0.017 15.1 0.1 3.8 7.4 0.2 2.3 2 0 0 2 2 2 0 NTPase CbiA PF01656.23 PSC71922.1 - 0.034 14.2 0.0 0.077 13.0 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_22 PF13401.6 PSC71922.1 - 0.051 13.8 0.4 2.4 8.4 0.0 3.6 4 0 0 4 4 4 0 AAA domain AAA_16 PF13191.6 PSC71922.1 - 0.063 13.7 1.7 0.27 11.6 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain FtsK_SpoIIIE PF01580.18 PSC71922.1 - 0.085 12.2 0.0 0.24 10.7 0.0 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family IstB_IS21 PF01695.17 PSC71922.1 - 0.11 12.2 0.0 0.27 10.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 PSC71922.1 - 0.18 11.0 0.0 0.75 9.0 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) cobW PF02492.19 PSC71922.1 - 0.2 11.2 0.0 0.35 10.4 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF3638 PF12340.8 PSC71922.1 - 0.21 10.9 0.2 0.42 9.9 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3638) eIF2A PF08662.11 PSC71923.1 - 5e-47 160.3 0.1 1.8e-44 151.9 0.0 3.1 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.22 PSC71923.1 - 5.2e-10 39.0 0.0 1.2e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ANAPC4_WD40 PF12894.7 PSC71923.1 - 6.2e-06 26.4 0.0 0.11 12.8 0.0 4.3 2 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PSC71923.1 - 0.0087 16.9 0.1 0.48 11.4 0.1 3.7 4 0 0 4 4 4 1 WD domain, G-beta repeat DapB_C PF05173.14 PSC71924.1 - 9.1e-21 74.1 0.1 1.3e-20 73.6 0.1 1.2 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, C-terminus DapB_N PF01113.20 PSC71924.1 - 8.1e-13 48.6 0.0 1.7e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Alfin PF12165.8 PSC71925.1 - 8.1e-61 203.3 0.0 1.1e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Alfin PHD PF00628.29 PSC71925.1 - 3.7e-09 36.3 9.4 1.5e-08 34.3 7.1 2.4 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 PSC71925.1 - 0.0023 17.4 4.9 0.86 9.2 1.4 2.7 2 0 0 2 2 2 2 PHD-finger zf-C2H2_jaz PF12171.8 PSC71925.1 - 0.25 11.7 2.3 10 6.5 0.1 3.1 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding GAGA PF09237.11 PSC71925.1 - 0.34 10.7 1.8 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 GAGA factor Prok-RING_1 PF14446.6 PSC71925.1 - 4.4 7.3 8.6 0.61 10.1 2.1 2.6 2 1 1 3 3 3 0 Prokaryotic RING finger family 1 zf-C2H2_4 PF13894.6 PSC71925.1 - 8.7 7.5 10.7 30 5.8 0.2 3.4 3 0 0 3 3 3 0 C2H2-type zinc finger Gpr1_Fun34_YaaH PF01184.19 PSC71926.1 - 1.5e-14 54.1 19.7 6.9e-11 42.1 13.6 2.3 1 1 1 2 2 2 2 GPR1/FUN34/yaaH family QCR10 PF09796.9 PSC71926.1 - 2.1 8.4 0.0 2.1 8.4 0.0 3.3 5 0 0 5 5 5 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Ank_2 PF12796.7 PSC71927.1 - 5.2e-17 62.2 0.1 1.8e-08 34.8 0.0 3.3 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC71927.1 - 2.4e-15 56.4 0.8 4.1e-08 33.3 0.1 3.1 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ion_trans PF00520.31 PSC71927.1 - 6.1e-12 45.3 4.9 9e-12 44.7 4.9 1.3 1 0 0 1 1 1 1 Ion transport protein Ank_4 PF13637.6 PSC71927.1 - 9.1e-10 38.9 0.3 1.4e-05 25.6 0.1 3.9 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC71927.1 - 1.3e-09 37.4 0.1 0.21 12.2 0.0 5.3 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 PSC71927.1 - 1.9e-09 37.5 0.1 0.0058 17.0 0.0 3.4 2 0 0 2 2 2 2 Ankyrin repeat cNMP_binding PF00027.29 PSC71927.1 - 5.4e-07 29.6 0.0 0.011 15.8 0.0 2.6 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain EamA PF00892.20 PSC71928.1 - 0.0024 18.1 2.3 0.0024 18.1 2.3 1.6 1 1 0 1 1 1 1 EamA-like transporter family MFS_3 PF05977.13 PSC71928.1 - 0.047 12.1 2.1 0.059 11.8 2.1 1.0 1 0 0 1 1 1 0 Transmembrane secretion effector Pkinase PF00069.25 PSC71930.1 - 9.1e-22 77.7 0.0 1.4e-21 77.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC71930.1 - 2.3e-17 63.1 0.0 5.4e-17 61.9 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Rhomboid PF01694.22 PSC71931.1 - 3.8e-22 78.9 10.4 6.5e-22 78.2 10.4 1.3 1 0 0 1 1 1 1 Rhomboid family Metallophos PF00149.28 PSC71931.1 - 1.3e-18 68.3 0.5 2.2e-18 67.5 0.5 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 PSC71931.1 - 2e-16 60.6 0.2 7.1e-16 58.8 0.0 2.0 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 PSC71931.1 - 2.2e-13 50.6 0.4 4.9e-12 46.2 0.0 3.1 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain DUF1751 PF08551.10 PSC71931.1 - 0.13 12.9 0.0 0.23 12.0 0.0 1.4 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) SVIP PF15811.5 PSC71931.1 - 0.6 10.6 16.6 0.025 15.0 8.6 2.2 2 0 0 2 2 2 0 Small VCP/p97-interacting protein Sec61_beta PF03911.16 PSC71932.1 - 7.1e-14 51.6 1.2 9.2e-14 51.2 1.2 1.2 1 0 0 1 1 1 1 Sec61beta family Pro_isomerase PF00160.21 PSC71934.1 - 1.9e-33 116.0 0.0 2.5e-33 115.6 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Fer4_9 PF13187.6 PSC71934.1 - 0.18 12.0 3.9 1.1 9.5 3.9 2.2 1 1 0 1 1 1 0 4Fe-4S dicluster domain Pkinase PF00069.25 PSC71935.1 - 2e-64 217.5 0.0 2.6e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC71935.1 - 9e-34 116.9 0.0 1.4e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC71935.1 - 7.7e-07 28.7 0.0 1.1e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PSC71935.1 - 0.00035 19.5 0.0 0.00076 18.4 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Seadorna_VP7 PF07387.11 PSC71935.1 - 0.065 12.3 0.5 0.11 11.6 0.1 1.4 2 0 0 2 2 2 0 Seadornavirus VP7 Rtt106 PF08512.12 PSC71936.1 - 5e-20 71.7 0.0 9.1e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Histone chaperone Rttp106-like CDC27 PF09507.10 PSC71936.1 - 2.2 7.6 20.3 3.2 7.1 20.3 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PPL5 PF18168.1 PSC71936.1 - 3.3 6.9 9.0 4.8 6.4 9.0 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Tub_N PF16322.5 PSC71936.1 - 4.2 7.7 23.5 6.4 7.1 23.5 1.2 1 0 0 1 1 1 0 Tubby N-terminal BUD22 PF09073.10 PSC71936.1 - 6.4 6.0 33.9 8.6 5.6 33.9 1.1 1 0 0 1 1 1 0 BUD22 F-box-like PF12937.7 PSC71937.1 - 3.5e-06 26.8 0.5 1.9e-05 24.4 0.5 2.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PSC71937.1 - 6.8e-05 22.6 0.0 0.00014 21.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain AP_endonuc_2 PF01261.24 PSC71938.1 - 0.041 13.3 0.1 0.043 13.2 0.1 1.1 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Complex1_51K PF01512.17 PSC71939.1 - 3.4e-47 160.1 0.0 5.1e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 PSC71939.1 - 4.3e-29 100.4 0.0 8.2e-29 99.5 0.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 PSC71939.1 - 2.7e-07 30.3 0.0 6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 SLBB domain rve PF00665.26 PSC71940.1 - 6.9e-19 68.2 0.0 1.5e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC71940.1 - 0.0063 16.3 0.0 0.016 14.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain DEAD PF00270.29 PSC71941.1 - 2.2e-40 138.3 0.0 3.1e-40 137.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC71941.1 - 3.2e-26 91.8 0.0 1.2e-24 86.7 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC71941.1 - 3.3e-07 30.5 0.0 4.8e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 PSC71941.1 - 0.022 13.5 0.0 0.032 13.0 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain Myb_DNA-binding PF00249.31 PSC71942.1 - 1.7e-06 28.1 0.0 2.5e-06 27.6 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain TEA PF01285.18 PSC71942.1 - 0.078 13.1 0.0 17 5.6 0.0 2.3 1 1 1 2 2 2 0 TEA/ATTS domain CGI-121 PF08617.10 PSC71943.1 - 1.3e-27 97.0 0.0 1.4e-27 96.8 0.0 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 ETF_alpha PF00766.19 PSC71943.1 - 0.098 12.7 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Electron transfer flavoprotein FAD-binding domain DUF4346 PF14251.6 PSC71945.1 - 2.7e-47 159.6 0.0 3.5e-47 159.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4346) Mito_carr PF00153.27 PSC71946.1 - 1.3e-63 210.9 13.1 4.7e-23 80.9 0.0 4.1 4 0 0 4 4 3 3 Mitochondrial carrier protein ABC_tran PF00005.27 PSC71946.1 - 3.9e-32 111.6 0.0 2.3e-31 109.1 0.0 2.1 2 0 0 2 2 2 1 ABC transporter ABC_membrane PF00664.23 PSC71946.1 - 7.2e-20 71.8 2.6 1.2e-19 71.1 2.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_16 PF13191.6 PSC71946.1 - 0.0002 21.8 0.2 0.00099 19.5 0.2 2.3 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 PSC71946.1 - 0.00021 20.8 0.0 0.051 13.0 0.0 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 PSC71946.1 - 0.00026 21.3 0.0 0.0018 18.6 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.6 PSC71946.1 - 0.0011 18.6 0.0 0.0028 17.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 PSC71946.1 - 0.0033 17.3 0.0 0.0053 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_33 PF13671.6 PSC71946.1 - 0.01 16.0 0.1 0.15 12.2 0.0 2.8 3 0 0 3 3 2 0 AAA domain AAA_18 PF13238.6 PSC71946.1 - 0.011 16.2 0.0 0.024 15.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 PSC71946.1 - 0.022 15.0 1.4 14 6.0 0.1 4.0 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 PSC71946.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase MMR_HSR1 PF01926.23 PSC71946.1 - 0.059 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase DUF87 PF01935.17 PSC71946.1 - 0.067 13.3 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain NTPase_1 PF03266.15 PSC71946.1 - 0.11 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 NTPase Cytidylate_kin PF02224.18 PSC71946.1 - 0.12 12.0 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_23 PF13476.6 PSC71946.1 - 0.13 12.7 0.0 0.23 11.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 PSC71946.1 - 0.15 12.0 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.15 PSC71946.1 - 0.16 11.9 0.0 0.27 11.1 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_24 PF13479.6 PSC71946.1 - 0.16 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 PSC71946.1 - 0.21 11.2 0.0 0.34 10.5 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SARAF PF06682.12 PSC71946.1 - 0.94 9.1 3.8 12 5.4 0.0 2.6 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Abhydrolase_1 PF00561.20 PSC71947.1 - 6.3e-12 45.7 0.3 7.5e-10 38.9 0.2 2.5 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 PSC71947.1 - 2.5e-06 27.5 0.0 9.2e-06 25.7 0.0 2.0 1 0 0 1 1 1 1 TAP-like protein Hydrolase_4 PF12146.8 PSC71947.1 - 0.00011 21.5 0.4 0.00051 19.4 0.0 2.2 2 1 0 2 2 2 1 Serine aminopeptidase, S33 CCDC53 PF10152.9 PSC71947.1 - 0.098 13.1 25.8 0.043 14.2 7.2 3.2 1 1 2 3 3 3 0 Subunit CCDC53 of WASH complex Peptidase_C69 PF03577.15 PSC71948.1 - 1.8e-81 274.1 0.0 2.3e-81 273.8 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C69 MttA_Hcf106 PF02416.16 PSC71949.1 - 1.7e-18 65.7 0.6 1.7e-18 65.7 0.6 1.8 2 0 0 2 2 2 1 mttA/Hcf106 family Yip1 PF04893.17 PSC71949.1 - 9.2e-08 32.0 26.4 9.2e-08 32.0 26.4 2.2 1 1 1 2 2 2 1 Yip1 domain DUF2070 PF09843.9 PSC71949.1 - 1.5 7.0 12.0 2.3 6.4 12.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) Ribosomal_L22 PF00237.19 PSC71950.1 - 2.5e-21 75.8 0.1 5.2e-21 74.8 0.1 1.5 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e KDZ PF18758.1 PSC71951.1 - 6.9e-25 88.0 3.8 1.1e-24 87.3 3.8 1.3 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Sedlin_N PF04628.13 PSC71952.1 - 1.6e-22 80.0 0.0 2e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 PSC71952.1 - 0.00037 20.5 0.0 0.00042 20.2 0.0 1.1 1 0 0 1 1 1 1 Sybindin-like family YchF-GTPase_C PF06071.13 PSC71953.1 - 1e-38 131.4 0.1 8.3e-37 125.2 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 PSC71953.1 - 4.3e-23 81.6 0.2 1.5e-22 79.8 0.0 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PSC71953.1 - 1.8e-07 30.8 0.0 7.7e-07 28.8 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B MMR_HSR1_C PF08438.10 PSC71953.1 - 0.033 14.8 0.8 0.056 14.0 0.1 1.7 2 0 0 2 2 2 0 GTPase of unknown function C-terminal AAA_18 PF13238.6 PSC71953.1 - 0.051 14.1 0.1 5.4 7.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 PSC71953.1 - 0.052 14.1 0.1 0.18 12.3 0.0 1.9 2 0 0 2 2 2 0 ABC transporter MutS_V PF00488.21 PSC71954.1 - 3.5e-79 265.2 0.1 5.5e-79 264.6 0.1 1.3 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 PSC71954.1 - 3.9e-27 95.7 0.8 8.3e-27 94.7 0.8 1.5 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 PSC71954.1 - 8.4e-09 35.7 0.4 8.4e-09 35.7 0.4 1.7 2 0 0 2 2 2 1 MutS family domain IV AAA_30 PF13604.6 PSC71954.1 - 0.074 12.8 1.2 0.28 10.9 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PSC71954.1 - 0.097 12.9 1.1 0.47 10.7 0.0 2.5 2 1 1 3 3 3 0 AAA domain AAA_23 PF13476.6 PSC71954.1 - 0.51 10.8 3.4 1.6 9.2 0.0 2.6 2 1 0 2 2 2 0 AAA domain TIP49 PF06068.13 PSC71955.1 - 1.2e-157 524.7 1.2 1.7e-157 524.1 1.2 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain Peptidase_C69 PF03577.15 PSC71955.1 - 1.5e-75 254.6 0.0 2.5e-75 253.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family C69 TIP49_C PF17856.1 PSC71955.1 - 4.6e-25 87.5 1.6 1e-24 86.4 1.1 1.9 2 0 0 2 2 1 1 TIP49 AAA-lid domain AAA PF00004.29 PSC71955.1 - 1.6e-09 38.3 1.2 5.2e-07 30.1 0.2 2.9 2 1 1 3 3 3 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PSC71955.1 - 1e-05 25.3 2.6 0.002 17.9 0.1 2.7 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 PSC71955.1 - 1.1e-05 24.9 0.6 2e-05 24.1 0.6 1.3 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_5 PF07728.14 PSC71955.1 - 5.5e-05 23.2 0.2 0.0055 16.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PSC71955.1 - 5.8e-05 23.4 0.1 0.41 10.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.6 PSC71955.1 - 0.0002 21.7 3.1 0.0015 18.9 3.1 2.2 1 1 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 PSC71955.1 - 0.00023 20.6 1.7 0.0038 16.6 0.7 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 PSC71955.1 - 0.00037 20.9 0.7 0.00037 20.9 0.7 2.3 2 1 0 2 2 2 1 AAA ATPase domain Sigma54_activat PF00158.26 PSC71955.1 - 0.0011 18.7 0.3 0.45 10.2 0.2 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 PSC71955.1 - 0.0052 16.1 0.5 0.012 14.9 0.5 1.5 1 0 0 1 1 1 1 Zeta toxin NACHT PF05729.12 PSC71955.1 - 0.0089 16.0 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 NACHT domain CBFD_NFYB_HMF PF00808.23 PSC71955.1 - 0.02 15.1 0.7 0.02 15.1 0.7 2.0 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone AAA_25 PF13481.6 PSC71955.1 - 0.023 14.3 0.2 0.058 13.0 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 PSC71955.1 - 0.029 14.8 0.9 0.13 12.7 0.8 2.1 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 PSC71955.1 - 0.032 13.8 0.7 0.065 12.8 0.1 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 PSC71955.1 - 0.033 14.2 0.3 0.078 13.0 0.3 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 PSC71955.1 - 0.043 13.2 0.4 0.092 12.1 0.4 1.6 1 0 0 1 1 1 0 KaiC AAA_28 PF13521.6 PSC71955.1 - 0.14 12.4 0.9 0.73 10.1 0.2 2.3 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 PSC71955.1 - 0.14 11.3 0.0 0.24 10.6 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.6 PSC71955.1 - 0.16 12.5 0.1 0.55 10.8 0.1 1.9 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 PSC71955.1 - 0.16 11.6 3.7 0.73 9.5 1.7 2.4 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 PSC71957.1 - 1.1e-51 174.7 0.0 1.2e-51 174.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PSC71957.1 - 1.1e-34 119.2 0.0 1.6e-34 118.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PSC71957.1 - 5.3e-15 55.3 0.0 5.8e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PSC71957.1 - 6.5e-07 28.9 0.0 8.3e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 PSC71957.1 - 4.6e-05 22.9 0.0 6.7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 PSC71957.1 - 9.2e-05 22.1 0.0 0.0012 18.4 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 PSC71957.1 - 0.00077 19.5 0.0 0.001 19.1 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 PSC71957.1 - 0.00093 18.8 0.0 0.33 10.5 0.0 2.1 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 PSC71957.1 - 0.0011 19.0 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 PSC71957.1 - 0.0021 17.8 0.0 0.054 13.2 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 PSC71957.1 - 0.0022 17.9 0.1 1 9.2 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase NACHT PF05729.12 PSC71957.1 - 0.0022 17.9 0.1 0.018 15.0 0.0 2.2 2 1 0 2 2 2 1 NACHT domain AAA_16 PF13191.6 PSC71957.1 - 0.006 17.0 0.3 0.011 16.1 0.3 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 PSC71957.1 - 0.022 14.8 0.0 0.033 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PSC71957.1 - 0.023 15.0 0.1 0.078 13.2 0.1 1.9 1 1 0 2 2 2 0 AAA domain TniB PF05621.11 PSC71957.1 - 0.06 12.8 0.0 0.097 12.1 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ABC_tran PF00005.27 PSC71957.1 - 0.066 13.7 0.0 0.12 12.9 0.0 1.5 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.20 PSC71957.1 - 0.068 12.3 0.3 0.29 10.2 0.2 1.6 1 1 1 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 PSC71957.1 - 0.1 12.1 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region ATP_bind_1 PF03029.17 PSC71957.1 - 0.13 12.0 0.0 5.7 6.6 0.1 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein HA2 PF04408.23 PSC71958.1 - 1.9e-18 66.7 0.0 4.5e-18 65.5 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PSC71958.1 - 3.1e-11 43.5 0.0 6.2e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PSC71958.1 - 4.7e-11 43.0 0.0 9e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PSC71958.1 - 3e-07 30.4 0.1 5.5e-07 29.5 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 PSC71958.1 - 6e-06 26.6 0.1 1.7e-05 25.1 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PSC71958.1 - 0.00033 21.0 0.1 0.00083 19.7 0.1 1.6 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PSC71958.1 - 0.0052 16.5 0.1 0.0052 16.5 0.1 2.2 2 0 0 2 2 1 1 AAA domain Helicase_RecD PF05127.14 PSC71958.1 - 0.0086 15.9 0.0 0.018 14.9 0.0 1.5 1 0 0 1 1 1 1 Helicase cobW PF02492.19 PSC71958.1 - 0.0099 15.5 0.4 0.9 9.1 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain T2SSE PF00437.20 PSC71958.1 - 0.011 14.8 0.1 0.041 13.0 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.27 PSC71958.1 - 0.029 14.9 0.5 0.68 10.4 0.2 2.8 2 1 0 2 2 2 0 ABC transporter Flavi_DEAD PF07652.14 PSC71958.1 - 0.034 14.1 0.0 0.061 13.3 0.0 1.4 1 0 0 1 1 1 0 Flavivirus DEAD domain AAA_23 PF13476.6 PSC71958.1 - 0.061 13.8 0.1 0.14 12.7 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 PSC71958.1 - 0.065 13.4 0.1 0.18 12.0 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 PSC71958.1 - 0.096 12.4 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PSC71958.1 - 0.1 13.0 3.9 0.18 12.2 1.0 2.8 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 PSC71958.1 - 0.16 12.4 0.0 0.44 11.0 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TrwB_AAD_bind PF10412.9 PSC71958.1 - 0.19 10.6 0.1 0.33 9.8 0.1 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DnaJ PF00226.31 PSC71959.1 - 6.3e-15 55.1 0.1 4.6e-10 39.5 0.0 2.4 2 0 0 2 2 2 2 DnaJ domain TPR_1 PF00515.28 PSC71959.1 - 3.6e-11 42.4 15.5 0.00014 21.6 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 PSC71959.1 - 3.4e-07 29.9 29.9 0.014 15.4 0.1 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 PSC71959.1 - 1.2e-06 28.1 5.4 1.2 9.4 0.2 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 PSC71959.1 - 8.8e-05 22.9 19.1 0.25 11.9 2.5 6.0 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 PSC71959.1 - 0.00012 22.2 33.2 0.2 12.0 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 PSC71959.1 - 0.0026 18.0 1.1 0.34 11.4 0.1 3.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 PSC71959.1 - 0.016 14.9 10.3 0.04 13.6 0.1 3.8 3 1 0 3 3 3 0 TPR repeat MIT PF04212.18 PSC71959.1 - 0.029 14.4 0.9 4.8 7.3 0.0 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 PSC71959.1 - 0.23 11.8 8.2 27 5.3 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat NYD-SP12_N PF15015.6 PSC71959.1 - 0.25 9.7 0.5 0.41 9.0 0.5 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal TPR_9 PF13371.6 PSC71959.1 - 1.5 9.0 14.9 0.12 12.5 3.5 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 PSC71959.1 - 4.1 8.1 54.8 0.54 10.9 5.4 7.8 6 2 2 8 8 6 0 Tetratricopeptide repeat DnaJ PF00226.31 PSC71960.1 - 6.2e-15 55.1 0.1 4.6e-10 39.5 0.0 2.4 2 0 0 2 2 2 2 DnaJ domain TPR_1 PF00515.28 PSC71960.1 - 3.6e-11 42.4 15.5 0.00014 21.6 0.0 7.1 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_2 PF07719.17 PSC71960.1 - 3.4e-07 29.9 29.9 0.014 15.4 0.1 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 PSC71960.1 - 1.2e-06 28.1 5.4 1.2 9.4 0.2 6.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 PSC71960.1 - 0.0001 22.8 19.3 0.26 11.8 2.6 6.0 3 3 3 6 6 6 3 Tetratricopeptide repeat TPR_12 PF13424.6 PSC71960.1 - 0.00012 22.3 33.2 0.19 12.0 0.1 6.1 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_17 PF13431.6 PSC71960.1 - 0.0025 18.1 1.1 0.34 11.4 0.1 3.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 PSC71960.1 - 0.016 14.9 10.3 0.04 13.6 0.1 3.8 3 1 0 3 3 3 0 TPR repeat MIT PF04212.18 PSC71960.1 - 0.029 14.5 0.9 4.8 7.3 0.0 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 PSC71960.1 - 0.23 11.8 8.2 27 5.3 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat NYD-SP12_N PF15015.6 PSC71960.1 - 0.25 9.7 0.5 0.41 9.0 0.5 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal TPR_9 PF13371.6 PSC71960.1 - 1.5 9.0 14.9 0.12 12.5 3.5 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 PSC71960.1 - 4.1 8.1 54.8 0.54 11.0 5.4 7.8 6 2 2 8 8 6 0 Tetratricopeptide repeat IU_nuc_hydro PF01156.19 PSC71961.1 - 5.1e-75 252.9 0.7 5.9e-75 252.7 0.7 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase SRP54 PF00448.22 PSC71962.1 - 1.2e-76 256.7 0.2 1.9e-76 256.1 0.2 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 PSC71962.1 - 5.6e-28 97.5 3.8 5.6e-28 97.5 3.8 2.4 2 0 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.19 PSC71962.1 - 2.4e-20 72.5 1.9 7.6e-20 70.9 1.9 2.0 1 0 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_33 PF13671.6 PSC71962.1 - 2.8e-06 27.5 0.1 1.8e-05 24.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PSC71962.1 - 1.4e-05 24.9 0.0 3.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PSC71962.1 - 0.00045 20.6 0.0 0.001 19.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.6 PSC71962.1 - 0.00099 19.5 0.0 0.0036 17.7 0.0 2.0 1 0 0 1 1 1 1 AAA domain cobW PF02492.19 PSC71962.1 - 0.001 18.7 0.2 0.0054 16.3 0.2 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 PSC71962.1 - 0.01 15.3 0.2 1.7 8.1 0.0 2.4 1 1 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 PSC71962.1 - 0.011 16.0 0.1 0.043 14.1 0.1 2.0 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 PSC71962.1 - 0.012 15.0 0.1 0.032 13.6 0.0 1.8 2 0 0 2 2 2 0 KaiC MMR_HSR1 PF01926.23 PSC71962.1 - 0.012 15.7 0.2 0.14 12.2 0.2 2.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase DUF373 PF04123.13 PSC71962.1 - 0.033 13.6 0.2 0.054 12.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2209 PF09974.9 PSC71962.1 - 0.041 14.2 0.2 0.09 13.1 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2209) ResIII PF04851.15 PSC71962.1 - 0.081 12.9 0.6 0.3 11.1 0.6 1.9 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CLP1_P PF16575.5 PSC71962.1 - 0.088 12.6 0.1 0.55 10.0 0.0 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop Zeta_toxin PF06414.12 PSC71962.1 - 0.11 11.8 0.0 0.19 11.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA PF00004.29 PSC71962.1 - 0.12 12.8 1.1 1.8 9.0 0.3 3.1 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.23 PSC71962.1 - 0.14 12.2 0.0 0.57 10.2 0.0 2.0 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ACCA PF03255.14 PSC71963.1 - 1.5e-56 190.3 0.0 2.8e-56 189.4 0.0 1.5 1 0 0 1 1 1 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit GTP1_OBG PF01018.22 PSC71963.1 - 2.5e-32 111.6 20.3 3.6e-21 75.4 11.1 3.0 3 0 0 3 3 3 2 GTP1/OBG MMR_HSR1 PF01926.23 PSC71963.1 - 2.3e-24 85.7 0.0 4.7e-22 78.2 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Carboxyl_trans PF01039.22 PSC71963.1 - 2.3e-12 46.3 0.0 3.8e-12 45.6 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain FeoB_N PF02421.18 PSC71963.1 - 1.2e-06 28.1 0.0 1.1e-05 25.0 0.0 2.3 3 0 0 3 3 3 1 Ferrous iron transport protein B Arf PF00025.21 PSC71963.1 - 0.0064 16.0 0.0 0.061 12.8 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family DUF1351 PF07083.11 PSC71963.1 - 0.0088 15.8 0.3 0.014 15.1 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1351) Dynamin_N PF00350.23 PSC71963.1 - 0.11 12.6 0.0 40 4.2 0.0 3.2 2 1 1 3 3 3 0 Dynamin family ABC_tran PF00005.27 PSC71963.1 - 0.12 12.8 0.0 0.31 11.6 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 PSC71963.1 - 0.15 12.6 0.0 0.33 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain Glyco_transf_92 PF01697.27 PSC71964.1 - 1.6e-16 60.7 0.0 2.5e-16 60.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PSC71964.1 - 3.3e-12 46.8 0.0 8.7e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 MLANA PF14991.6 PSC71964.1 - 0.0024 18.1 0.0 0.0055 17.0 0.0 1.6 1 0 0 1 1 1 1 Protein melan-A Herpes_gE PF02480.16 PSC71964.1 - 0.066 12.0 0.1 0.13 11.0 0.1 1.5 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E TMEM51 PF15345.6 PSC71964.1 - 0.12 12.1 0.1 0.24 11.2 0.1 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 BatD PF13584.6 PSC71964.1 - 0.19 10.5 0.3 0.27 10.0 0.3 1.1 1 0 0 1 1 1 0 Oxygen tolerance DUF4381 PF14316.6 PSC71964.1 - 1.1 9.5 11.9 0.036 14.3 4.1 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DNA_gyraseB PF00204.25 PSC71965.1 - 1.8e-53 180.6 0.0 2.7e-53 180.0 0.0 1.3 1 0 0 1 1 1 1 DNA gyrase B DNA_gyraseB_C PF00986.21 PSC71965.1 - 1.1e-26 92.7 0.3 2.8e-26 91.5 0.1 1.8 2 0 0 2 2 2 1 DNA gyrase B subunit, carboxyl terminus HATPase_c PF02518.26 PSC71965.1 - 5.6e-20 71.9 0.1 1.1e-19 71.0 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 PSC71965.1 - 1.5e-14 54.0 0.0 3.9e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 Toprim domain HATPase_c_3 PF13589.6 PSC71965.1 - 0.041 13.7 0.0 0.093 12.6 0.0 1.6 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PT PF04886.12 PSC71966.1 - 0.047 13.2 21.4 0.88 9.2 0.8 4.2 4 0 0 4 4 4 0 PT repeat TraW_N PF12477.8 PSC71966.1 - 0.1 12.6 19.3 0.62 10.1 0.7 4.0 3 0 0 3 3 3 0 Sex factor F TraW protein N terminal B3 PF02362.21 PSC71967.1 - 1.2e-13 50.8 0.0 1.9e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 B3 DNA binding domain Macoilin PF09726.9 PSC71967.1 - 0.2 10.2 4.8 0.23 10.0 4.8 1.1 1 0 0 1 1 1 0 Macoilin family Activator_LAG-3 PF11498.8 PSC71967.1 - 0.27 10.2 26.6 0.45 9.4 26.6 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Hid1 PF12722.7 PSC71967.1 - 0.96 7.5 5.4 1.1 7.3 5.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ripply PF14998.6 PSC71967.1 - 1.2 9.8 0.0 1.2 9.8 0.0 2.9 2 1 0 2 2 2 0 Transcription Regulator Glyco_hydro_79C PF16862.5 PSC71967.1 - 1.3 9.9 4.2 11 7.0 0.0 2.4 2 0 0 2 2 2 0 Glycosyl hydrolase family 79 C-terminal beta domain DUF702 PF05142.12 PSC71967.1 - 2 8.8 8.0 56 4.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF702) NARP1 PF12569.8 PSC71967.1 - 7.9 5.3 12.6 12 4.7 12.6 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 rve PF00665.26 PSC71968.1 - 1.1e-18 67.5 0.0 2.5e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain CBFB_NFYA PF02045.15 PSC71968.1 - 4.4e-07 30.4 4.1 4.4e-07 30.4 4.1 2.7 3 0 0 3 3 3 1 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B rve_3 PF13683.6 PSC71968.1 - 0.0076 16.0 0.0 0.025 14.4 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain DUF4551 PF15087.6 PSC71968.1 - 4.9 5.9 9.2 9.3 4.9 9.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) HMG_box PF00505.19 PSC71969.1 - 7.8e-25 87.1 2.1 7.8e-25 87.1 2.1 1.7 2 0 0 2 2 2 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PSC71969.1 - 2.5e-16 60.0 2.1 2.5e-16 60.0 2.1 1.5 2 0 0 2 2 2 1 HMG-box domain HMG_box_5 PF14887.6 PSC71969.1 - 0.0011 18.8 2.6 0.0011 18.8 2.6 2.2 1 1 1 2 2 2 1 HMG (high mobility group) box 5 Gpr1_Fun34_YaaH PF01184.19 PSC71970.1 - 1.5e-14 54.1 19.7 6.9e-11 42.1 13.6 2.3 1 1 1 2 2 2 2 GPR1/FUN34/yaaH family QCR10 PF09796.9 PSC71970.1 - 2.1 8.4 0.0 2.1 8.4 0.0 3.3 5 0 0 5 5 5 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) C2 PF00168.30 PSC71971.1 - 1.8e-12 47.4 0.0 2.9e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 C2 domain MMM1 PF10296.9 PSC71971.1 - 0.047 12.7 0.0 0.076 12.0 0.0 1.2 1 0 0 1 1 1 0 Maintenance of mitochondrial morphology protein 1 Apc15p PF05841.11 PSC71971.1 - 0.17 12.7 0.9 1.6 9.6 0.1 2.5 2 0 0 2 2 2 0 Apc15p protein Pro_isomerase PF00160.21 PSC71972.1 - 2.3e-54 184.0 0.0 2.5e-54 183.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF3830 PF12903.7 PSC71972.1 - 0.04 13.6 0.0 0.089 12.5 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3830) SelP_C PF04593.14 PSC71973.1 - 0.038 14.0 0.3 0.077 13.0 0.3 1.4 1 0 0 1 1 1 0 Selenoprotein P, C terminal region HC2 PF07382.11 PSC71973.1 - 1.6 8.8 13.8 3 7.9 13.8 1.4 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Baculo_PEP_C PF04513.12 PSC71975.1 - 0.00027 21.0 0.4 0.00038 20.5 0.4 1.2 1 0 0 1 1 1 1 Baculovirus polyhedron envelope protein, PEP, C terminus DUF3606 PF12244.8 PSC71975.1 - 0.022 14.7 0.8 0.12 12.3 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3606) Flp_Fap PF04964.14 PSC71975.1 - 0.044 13.6 0.3 0.12 12.3 0.0 1.8 2 0 0 2 2 2 0 Flp/Fap pilin component LSM PF01423.22 PSC71977.1 - 1.5e-11 43.8 0.2 4.6e-11 42.2 0.2 1.8 1 1 0 1 1 1 1 LSM domain Golgin_A5 PF09787.9 PSC71978.1 - 9.4e-17 61.4 34.5 1.5e-16 60.7 3.1 3.9 1 1 2 3 3 3 3 Golgin subfamily A member 5 GAS PF13851.6 PSC71978.1 - 1.1 8.6 39.7 0.3 10.4 19.9 2.5 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Jnk-SapK_ap_N PF09744.9 PSC71978.1 - 1.2 9.4 42.4 0.44 10.8 15.6 3.8 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 IFT57 PF10498.9 PSC71978.1 - 1.5 7.7 14.5 1.5 7.7 4.6 2.5 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 DUF1664 PF07889.12 PSC71978.1 - 3.9 7.5 11.3 0.26 11.3 0.7 3.7 1 1 3 5 5 5 0 Protein of unknown function (DUF1664) Surfac_D-trimer PF09006.11 PSC71978.1 - 4.2 7.3 9.4 1.6 8.6 0.4 4.2 4 1 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation Leu_zip PF15294.6 PSC71978.1 - 5.3 6.5 34.1 0.42 10.1 3.4 3.1 1 1 2 3 3 3 0 Leucine zipper Pox_A_type_inc PF04508.12 PSC71978.1 - 6.5 6.8 7.8 20 5.2 0.0 4.7 4 0 0 4 4 4 0 Viral A-type inclusion protein repeat Fez1 PF06818.15 PSC71978.1 - 9.8 6.6 41.7 25 5.2 20.1 3.1 1 1 2 3 3 3 0 Fez1 Aldo_ket_red PF00248.21 PSC71979.1 - 2.7e-50 171.2 0.0 3.8e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family LEP503 PF15221.6 PSC71979.1 - 0.06 13.7 0.1 0.15 12.4 0.1 1.6 1 0 0 1 1 1 0 Lens epithelial cell protein LEP503 SBP PF03110.14 PSC71981.1 - 1.7e-22 79.5 4.6 3.8e-22 78.4 4.6 1.6 1 0 0 1 1 1 1 SBP domain MFS_1 PF07690.16 PSC71982.1 - 2.4e-16 59.6 35.1 4.9e-16 58.6 35.1 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily SPX PF03105.19 PSC71982.1 - 2.7e-12 47.3 4.9 1.1e-05 25.6 0.0 3.5 3 1 1 4 4 4 3 SPX domain OATP PF03137.20 PSC71982.1 - 0.00037 18.9 2.6 0.011 14.1 0.3 2.3 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family Spore_III_AB PF09548.10 PSC71982.1 - 0.035 14.2 0.1 0.14 12.2 0.1 2.0 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) CPBP PF02517.16 PSC71982.1 - 8.6 6.8 9.3 0.35 11.3 0.5 3.2 2 2 1 3 3 3 0 CPBP intramembrane metalloprotease Ank_2 PF12796.7 PSC71983.1 - 1e-24 86.9 1.2 5.9e-09 36.4 0.1 4.1 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PSC71983.1 - 4.6e-19 66.5 5.3 0.004 17.5 0.0 6.2 6 0 0 6 6 5 5 Ankyrin repeat Ank_4 PF13637.6 PSC71983.1 - 8.6e-19 67.7 1.5 2.2e-07 31.3 0.5 4.4 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC71983.1 - 1.4e-18 66.7 6.0 0.00087 19.6 0.0 5.7 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 PSC71983.1 - 4.6e-18 64.8 10.9 0.00032 21.0 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat zf-C3HC4_3 PF13920.6 PSC71983.1 - 2.1e-09 37.1 6.0 5.7e-09 35.7 6.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC71983.1 - 3.8e-06 26.7 7.5 9.6e-06 25.4 7.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC71983.1 - 0.0001 22.6 7.6 0.0001 22.6 7.6 1.8 2 0 0 2 2 1 1 Ring finger domain Prok-RING_4 PF14447.6 PSC71983.1 - 0.00018 21.3 7.0 0.00018 21.3 7.0 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PSC71983.1 - 0.0024 17.8 7.9 0.0024 17.8 7.9 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PSC71983.1 - 0.0038 17.0 8.8 0.0038 17.0 8.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Baculo_IE-1 PF05290.11 PSC71983.1 - 0.1 12.5 0.7 0.18 11.8 0.7 1.3 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_10 PF16685.5 PSC71983.1 - 0.6 10.3 5.8 1.7 8.9 5.8 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 PSC71983.1 - 0.61 10.2 2.3 0.57 10.3 0.6 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 PSC71983.1 - 0.62 10.4 3.2 1.7 9.0 3.2 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 PSC71983.1 - 0.69 10.0 4.8 1.8 8.7 4.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.6 PSC71983.1 - 0.85 9.5 6.9 1.8 8.4 6.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 PSC71983.1 - 1.1 9.4 7.2 0.49 10.6 4.2 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING ABC_membrane_2 PF06472.15 PSC71984.1 - 1e-41 143.2 0.1 1.2e-41 142.9 0.1 1.0 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 SbmA_BacA PF05992.12 PSC71984.1 - 1.1e-12 48.0 1.7 1.4e-11 44.4 1.7 2.0 1 1 0 1 1 1 1 SbmA/BacA-like family ABC_membrane PF00664.23 PSC71984.1 - 0.00015 21.5 0.3 0.00018 21.2 0.3 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region TssO PF17561.2 PSC71984.1 - 0.038 14.1 0.0 0.059 13.5 0.0 1.3 1 0 0 1 1 1 0 Type VI secretion system, TssO HlyIII PF03006.20 PSC71985.1 - 2.1e-33 116.0 7.5 2.3e-33 115.8 7.5 1.0 1 0 0 1 1 1 1 Haemolysin-III related Thioredoxin PF00085.20 PSC71986.1 - 3.8e-22 78.2 0.3 5.1e-22 77.8 0.3 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PSC71986.1 - 1.3e-05 25.6 0.2 4.2e-05 23.9 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PSC71986.1 - 6.8e-05 23.1 0.0 0.00022 21.5 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 PSC71986.1 - 0.005 16.7 0.1 0.007 16.3 0.1 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 PSC71986.1 - 0.022 14.5 0.1 0.043 13.6 0.1 1.5 2 0 0 2 2 2 0 Thioredoxin ADH_N PF08240.12 PSC71987.1 - 1.7e-05 24.6 5.1 2.3 8.1 0.4 4.6 1 1 4 5 5 5 5 Alcohol dehydrogenase GroES-like domain AhpC-TSA_2 PF13911.6 PSC71988.1 - 7.4e-16 58.3 0.0 8.8e-16 58.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme LRR_8 PF13855.6 PSC71989.1 - 1.1e-08 34.7 0.0 5e-06 26.2 0.0 2.5 1 1 1 2 2 2 2 Leucine rich repeat LRR_1 PF00560.33 PSC71989.1 - 0.00014 21.9 0.0 10 7.1 0.0 4.1 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_4 PF12799.7 PSC71989.1 - 0.0003 21.1 0.0 0.12 12.8 0.0 2.5 1 1 0 2 2 2 2 Leucine Rich repeats (2 copies) Glug PF07581.12 PSC71989.1 - 0.35 11.4 4.5 11 6.7 0.0 3.3 3 0 0 3 3 3 0 The GLUG motif PALP PF00291.25 PSC71990.1 - 6.3e-78 262.2 3.5 8.8e-78 261.7 3.5 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Thr_dehydrat_C PF00585.18 PSC71990.1 - 2.2e-14 53.0 0.0 2.1e-09 37.0 0.0 2.3 2 0 0 2 2 2 2 C-terminal regulatory domain of Threonine dehydratase CSD PF00313.22 PSC71991.1 - 1e-23 83.0 10.4 1.9e-09 37.2 0.0 6.2 6 0 0 6 6 6 5 'Cold-shock' DNA-binding domain CusF_Ec PF11604.8 PSC71991.1 - 0.1 12.6 0.6 6.3 6.9 0.0 3.6 4 1 1 5 5 5 0 Copper binding periplasmic protein CusF Mad3_BUB1_I PF08311.12 PSC71993.1 - 4.8e-37 126.7 0.0 8.1e-37 126.0 0.0 1.4 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 PSC71993.1 - 2.3e-12 46.9 0.0 4.3e-10 39.4 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 PSC71993.1 - 0.0062 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PSC71993.1 - 0.0073 16.3 0.1 0.0073 16.3 0.1 4.7 7 0 0 7 7 7 1 Phosphotransferase enzyme family Mad3_BUB1_I_2 PF17014.5 PSC71993.1 - 0.04 14.0 0.0 0.07 13.3 0.0 1.3 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Pentapeptide_2 PF01469.18 PSC71994.1 - 7.6e-09 35.3 19.8 7.6e-09 35.3 19.8 2.0 1 1 1 2 2 2 2 Pentapeptide repeats (8 copies) PAN_2 PF08276.11 PSC71994.1 - 0.015 15.4 1.2 0.052 13.7 0.2 2.5 2 0 0 2 2 2 0 PAN-like domain PP2C PF00481.21 PSC71995.1 - 1.1e-45 156.3 0.1 2.3e-28 99.5 0.0 3.1 2 1 1 3 3 3 3 Protein phosphatase 2C Ribosomal_S5 PF00333.20 PSC71995.1 - 1.8e-28 98.3 2.3 5.4e-28 96.8 2.3 1.9 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 PSC71995.1 - 4.4e-24 83.7 0.0 8.2e-24 82.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain BAT2_N PF07001.11 PSC71995.1 - 5.2 7.5 18.1 0.31 11.5 2.2 2.7 3 0 0 3 3 3 0 BAT2 N-terminus COPIIcoated_ERV PF07970.12 PSC71996.1 - 7.1e-39 133.9 0.0 1.2e-38 133.2 0.0 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 PSC71996.1 - 1.9e-21 76.2 0.1 3.1e-21 75.5 0.1 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Ribosomal_S16 PF00886.19 PSC71997.1 - 2.6e-20 72.2 0.1 5.9e-20 71.1 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S16 SF-assemblin PF06705.11 PSC71997.1 - 0.21 10.9 5.8 0.32 10.3 5.8 1.2 1 0 0 1 1 1 0 SF-assemblin/beta giardin Golgin_A5 PF09787.9 PSC71997.1 - 1 8.8 7.3 1.6 8.1 7.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DNase_II PF03265.15 PSC71998.1 - 1.2e-35 123.3 0.0 1.9e-35 122.7 0.0 1.2 1 0 0 1 1 1 1 Deoxyribonuclease II Mad3_BUB1_I PF08311.12 PSC72001.1 - 5.5e-37 126.5 0.0 9.1e-37 125.8 0.0 1.3 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Pkinase PF00069.25 PSC72001.1 - 2.8e-12 46.6 0.0 4.9e-10 39.2 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Kdo PF06293.14 PSC72001.1 - 0.0071 15.7 0.0 0.013 14.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PSC72001.1 - 0.0082 16.1 0.1 0.0082 16.1 0.1 4.4 6 0 0 6 6 6 1 Phosphotransferase enzyme family Mad3_BUB1_I_2 PF17014.5 PSC72001.1 - 0.045 13.9 0.0 0.074 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Lipase_GDSL_2 PF13472.6 PSC72002.1 - 4.9e-15 56.4 0.1 1.1e-14 55.3 0.1 1.6 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 PSC72002.1 - 0.00014 22.0 0.0 0.00019 21.5 0.0 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Cyclin_N PF00134.23 PSC72002.1 - 0.0047 16.7 0.4 0.031 14.0 0.0 2.3 2 1 0 2 2 2 1 Cyclin, N-terminal domain CBM53 PF16760.5 PSC72003.1 - 9.2e-44 147.9 0.0 9.2e-15 55.0 0.0 3.6 3 0 0 3 3 3 3 Starch/carbohydrate-binding module (family 53) Glyco_transf_5 PF08323.11 PSC72003.1 - 1.7e-39 136.0 2.0 2.5e-37 128.9 2.0 2.5 1 1 0 1 1 1 1 Starch synthase catalytic domain Glyco_transf_4 PF13439.6 PSC72003.1 - 1.7e-11 44.4 0.3 9.3e-11 42.0 0.3 2.3 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 PSC72003.1 - 3.4e-09 37.3 2.3 1e-08 35.8 0.0 3.2 3 1 1 4 4 4 1 Glycosyl transferase 4-like domain DUF4763 PF15960.5 PSC72003.1 - 0.023 14.0 4.3 0.044 13.1 4.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) Glyco_trans_4_2 PF13477.6 PSC72003.1 - 0.023 14.7 0.1 3.9 7.5 0.0 2.4 2 0 0 2 2 2 0 Glycosyl transferase 4-like Glycos_transf_1 PF00534.20 PSC72003.1 - 0.03 13.9 0.0 0.24 10.9 0.0 2.2 1 1 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PSC72003.1 - 0.048 14.1 0.0 0.15 12.5 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferases group 1 IZUMO PF15005.6 PSC72003.1 - 0.86 10.1 2.2 2.2 8.8 2.2 1.6 1 0 0 1 1 1 0 Izumo sperm-egg fusion, Ig domain-associated FapA PF03961.13 PSC72003.1 - 1.9 7.0 5.1 3.9 6.0 5.1 1.4 1 0 0 1 1 1 0 Flagellar Assembly Protein A Jnk-SapK_ap_N PF09744.9 PSC72003.1 - 2.5 8.3 15.0 0.066 13.4 5.2 2.4 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 polyprenyl_synt PF00348.17 PSC72004.1 - 2e-59 200.7 0.1 2.4e-59 200.5 0.1 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase TPPII_N PF12583.8 PSC72005.1 - 4.4 7.9 11.7 8.5 7.0 11.7 1.4 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal TIC20 PF16166.5 PSC72006.1 - 2.4e-35 122.0 1.0 3e-35 121.6 1.0 1.1 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like F-box-like PF12937.7 PSC72007.1 - 0.15 12.0 0.8 8 6.4 0.0 2.6 2 0 0 2 2 2 0 F-box-like 5-FTHF_cyc-lig PF01812.20 PSC72008.1 - 3.2e-34 118.4 0.0 4.6e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family zf-RING_2 PF13639.6 PSC72011.1 - 5.7e-11 42.6 2.8 9.1e-11 41.9 2.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PSC72011.1 - 1.8e-09 37.2 1.1 4.4e-09 35.9 1.1 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 PSC72011.1 - 1.7e-07 31.0 1.1 2.6e-07 30.4 1.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC72011.1 - 8.8e-06 25.6 2.4 1.6e-05 24.8 1.1 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 PSC72011.1 - 1.1e-05 25.7 2.4 2.2e-05 24.6 2.4 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 PSC72011.1 - 4.1e-05 23.3 4.3 0.00013 21.7 4.4 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC72011.1 - 0.00011 22.0 0.8 0.00018 21.4 0.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PSC72011.1 - 0.0034 17.2 0.9 0.0056 16.5 0.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PSC72011.1 - 0.0066 16.5 0.6 0.015 15.4 0.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 PSC72011.1 - 0.023 14.3 0.7 0.038 13.6 0.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 PSC72011.1 - 0.055 13.4 1.3 0.083 12.8 1.3 1.3 1 0 0 1 1 1 0 PHD-finger Prok-RING_1 PF14446.6 PSC72011.1 - 0.064 13.2 2.1 0.47 10.4 0.8 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Armet PF10208.9 PSC72011.1 - 0.099 12.6 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding Prok-RING_4 PF14447.6 PSC72011.1 - 0.14 12.1 2.4 0.25 11.2 2.4 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.7 PSC72011.1 - 0.23 11.6 1.0 0.77 9.9 0.9 1.9 1 1 1 2 2 2 0 RING-variant domain zf-C3HC4_4 PF15227.6 PSC72011.1 - 0.24 11.6 3.4 1.2 9.4 3.6 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.8 PSC72011.1 - 0.29 11.3 3.4 0.79 9.9 3.4 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Acyltransferase PF01553.21 PSC72012.1 - 1.1e-17 63.9 0.0 2e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase SR-25 PF10500.9 PSC72012.1 - 2.1 7.9 7.1 3.4 7.2 7.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Apolipoprotein PF01442.18 PSC72012.1 - 3.2 7.6 11.8 2.1 8.2 1.3 2.7 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Barwin PF00967.17 PSC72013.1 - 0.00023 21.0 0.5 0.00034 20.4 0.5 1.4 1 0 0 1 1 1 1 Barwin family SR-25 PF10500.9 PSC72013.1 - 0.0051 16.4 2.9 0.0066 16.1 2.9 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DPBB_1 PF03330.18 PSC72013.1 - 0.047 14.0 0.1 0.1 12.9 0.1 1.5 1 1 0 1 1 1 0 Lytic transglycolase Hist_deacetyl PF00850.19 PSC72014.1 - 1.5e-55 188.8 0.0 6.5e-38 130.9 0.0 2.6 2 0 0 2 2 2 2 Histone deacetylase domain Ank_2 PF12796.7 PSC72014.1 - 3e-23 82.2 1.5 2.7e-08 34.3 0.4 4.1 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC72014.1 - 4.6e-17 61.9 11.1 0.00018 21.7 1.2 5.7 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC72014.1 - 7.4e-17 61.5 5.9 1.4e-05 25.6 0.1 4.5 2 2 0 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC72014.1 - 1.4e-15 55.8 8.1 0.0058 17.1 0.0 6.8 6 0 0 6 6 6 5 Ankyrin repeat Ank PF00023.30 PSC72014.1 - 3.2e-12 46.3 16.7 0.088 13.3 0.4 6.6 6 0 0 6 6 6 5 Ankyrin repeat CSTF_C PF14304.6 PSC72014.1 - 0.19 11.4 1.9 12 5.6 0.0 2.4 2 0 0 2 2 2 0 Transcription termination and cleavage factor C-terminal Xpo1 PF08389.12 PSC72015.1 - 2.5e-32 112.0 0.0 3.6e-31 108.3 0.0 2.7 2 0 0 2 2 2 1 Exportin 1-like protein HEAT PF02985.22 PSC72015.1 - 0.0041 17.3 8.0 6.6 7.3 0.1 6.6 7 0 0 7 7 7 2 HEAT repeat zf-MYND PF01753.18 PSC72017.1 - 3.9e-06 26.8 17.5 7e-06 26.0 17.5 1.4 1 0 0 1 1 1 1 MYND finger RRM_1 PF00076.22 PSC72017.1 - 0.00016 21.4 0.0 0.00034 20.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-HC5HC2H_2 PF13832.6 PSC72018.1 - 2.6e-20 72.6 8.6 2.6e-20 72.6 8.6 2.4 2 0 0 2 2 2 1 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 PSC72018.1 - 1.3e-15 57.5 4.2 1.3e-15 57.5 4.2 2.7 2 0 0 2 2 2 1 PHD-like zinc-binding domain SET PF00856.28 PSC72018.1 - 2e-15 57.6 0.1 2e-15 57.6 0.1 3.7 3 1 0 3 3 3 1 SET domain FYRC PF05965.14 PSC72018.1 - 9.9e-11 41.7 0.0 2.7e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 F/Y rich C-terminus PHD_2 PF13831.6 PSC72018.1 - 7.6e-10 38.2 2.8 7.6e-10 38.2 2.8 2.6 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 PSC72018.1 - 1.3e-07 31.4 8.2 1.3e-07 31.4 8.2 3.5 3 0 0 3 3 3 1 PHD-finger FYRN PF05964.14 PSC72018.1 - 2.6e-07 30.4 0.0 5.6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 F/Y-rich N-terminus PWWP PF00855.17 PSC72018.1 - 2.7e-06 27.7 0.0 7.5e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 PWWP domain LBR_tudor PF09465.10 PSC72018.1 - 0.0043 16.8 0.1 0.0082 15.9 0.1 1.3 1 0 0 1 1 1 1 Lamin-B receptor of TUDOR domain S6PP PF05116.13 PSC72019.1 - 1.1e-72 244.5 0.0 1.4e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 PSC72019.1 - 4.3e-13 49.6 0.0 2.1e-10 40.8 0.0 2.4 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase S6PP_C PF08472.10 PSC72019.1 - 0.047 13.5 0.0 8.1 6.3 0.0 2.5 2 0 0 2 2 2 0 Sucrose-6-phosphate phosphohydrolase C-terminal PikAIV_N PF18605.1 PSC72019.1 - 0.094 12.3 0.1 0.094 12.3 0.1 1.8 2 0 0 2 2 2 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DUF563 PF04577.14 PSC72020.1 - 1.4e-06 28.6 0.0 3.9e-06 27.2 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF563) bZIP_1 PF00170.21 PSC72020.1 - 0.00015 21.8 12.2 0.00041 20.4 6.4 2.6 1 1 1 2 2 2 2 bZIP transcription factor bZIP_2 PF07716.15 PSC72020.1 - 0.00059 19.9 9.0 0.0012 18.9 8.4 1.9 1 1 0 1 1 1 1 Basic region leucine zipper Skp1 PF01466.19 PSC72021.1 - 1.1e-28 99.1 1.4 2.8e-28 97.8 1.4 1.8 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Gar1 PF04410.14 PSC72021.1 - 3.8e-25 88.5 0.0 1.7e-24 86.3 0.0 2.1 2 0 0 2 2 2 1 Gar1/Naf1 RNA binding region Skp1_POZ PF03931.15 PSC72021.1 - 7.1e-23 80.5 0.5 7.1e-23 80.5 0.5 2.3 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain XPC-binding PF09280.11 PSC72022.1 - 0.026 14.2 0.4 8.9 6.1 0.0 3.7 3 0 0 3 3 3 0 XPC-binding domain HEAT PF02985.22 PSC72022.1 - 6.4 7.3 13.6 0.36 11.2 1.1 3.9 3 0 0 3 3 3 0 HEAT repeat DAO PF01266.24 PSC72023.1 - 5.3e-51 174.3 0.2 7.5e-51 173.8 0.2 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase DAO_C PF16901.5 PSC72023.1 - 6.2e-37 126.3 0.0 1.1e-36 125.5 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of alpha-glycerophosphate oxidase FAD_binding_2 PF00890.24 PSC72023.1 - 4.9e-12 45.6 3.4 3.8e-05 23.0 1.2 2.2 2 0 0 2 2 2 2 FAD binding domain FAD_oxidored PF12831.7 PSC72023.1 - 1.2e-08 34.8 0.1 9.1e-07 28.6 0.1 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 PSC72023.1 - 9.6e-08 31.6 0.3 0.0059 15.9 0.1 2.7 2 1 0 3 3 3 2 FAD binding domain Pyr_redox_2 PF07992.14 PSC72023.1 - 7.3e-05 22.1 0.3 0.0003 20.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PSC72023.1 - 0.00021 20.5 0.5 0.0018 17.4 0.2 2.0 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 PSC72023.1 - 0.00054 18.8 0.3 0.00081 18.2 0.3 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_8 PF13450.6 PSC72023.1 - 0.00071 19.8 0.4 0.0025 18.0 0.3 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 PSC72023.1 - 0.002 18.7 0.3 0.028 15.0 0.1 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PSC72023.1 - 0.019 14.2 0.1 0.037 13.2 0.1 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_3 PF13738.6 PSC72023.1 - 0.03 13.6 0.1 0.051 12.8 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 PSC72023.1 - 0.2 11.5 0.1 0.35 10.7 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Cytochrom_C1 PF02167.15 PSC72024.1 - 1.1e-95 319.6 0.0 1.3e-95 319.3 0.0 1.1 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 PSC72024.1 - 0.0041 17.4 0.0 0.0092 16.3 0.0 1.7 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 PSC72024.1 - 0.013 16.6 3.4 0.12 13.6 1.0 2.9 2 1 0 2 2 2 0 Cytochrome c Pkinase PF00069.25 PSC72025.1 - 2.5e-53 181.1 0.0 3.4e-53 180.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC72025.1 - 7.5e-39 133.6 0.0 1e-38 133.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC72025.1 - 0.00088 18.7 0.0 0.0039 16.5 0.0 2.0 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 PSC72025.1 - 0.019 14.3 0.0 0.035 13.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PSC72025.1 - 0.28 9.9 0.0 0.43 9.3 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase TFIIA PF03153.13 PSC72026.1 - 1.1 9.2 15.1 0.15 12.1 6.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4430 PF14478.6 PSC72027.1 - 0.1 13.2 0.0 0.19 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4430) Pkinase_Tyr PF07714.17 PSC72028.1 - 7.8e-53 179.4 0.0 2.4e-52 177.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC72028.1 - 6.2e-50 170.0 0.0 1.3e-49 169.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.7 PSC72028.1 - 2.5e-19 69.1 9.8 5.5e-06 26.6 0.0 5.3 3 1 1 5 5 5 5 Leucine Rich repeats (2 copies) His_Phos_1 PF00300.22 PSC72028.1 - 3.3e-10 40.0 0.4 3.3e-10 40.0 0.4 2.5 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) LRR_8 PF13855.6 PSC72028.1 - 3.2e-06 26.8 16.6 0.00061 19.5 0.1 5.3 2 2 4 6 6 6 2 Leucine rich repeat MRP-L46 PF11788.8 PSC72028.1 - 1.4e-05 25.8 0.1 1.4e-05 25.8 0.1 3.9 3 1 1 4 4 4 1 39S mitochondrial ribosomal protein L46 LRRNT_2 PF08263.12 PSC72028.1 - 0.074 13.4 0.2 0.24 11.7 0.2 1.9 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain SKG6 PF08693.10 PSC72028.1 - 0.15 11.5 3.6 0.38 10.2 3.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EphA2_TM PF14575.6 PSC72028.1 - 2.8 8.9 0.0 2.8 8.9 0.0 3.0 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain LRR_1 PF00560.33 PSC72028.1 - 4.3 8.3 10.8 44 5.2 0.0 6.0 6 1 0 6 6 6 0 Leucine Rich Repeat DUF829 PF05705.14 PSC72029.1 - 7.2e-43 147.2 2.8 1.3e-26 94.0 1.3 2.1 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF829) DUF218 PF02698.17 PSC72030.1 - 4.1e-16 59.2 0.2 5.9e-14 52.2 0.0 2.3 1 1 1 2 2 2 2 DUF218 domain DUF218 PF02698.17 PSC72031.1 - 4.8e-15 55.8 0.1 3.3e-14 53.0 0.0 2.0 1 1 0 2 2 2 1 DUF218 domain rve PF00665.26 PSC72032.1 - 9.5e-19 67.8 0.0 2e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC72032.1 - 0.0077 16.0 0.0 0.021 14.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain EF-hand_1 PF00036.32 PSC72033.1 - 5.2e-24 82.0 4.4 4.6e-05 22.7 0.4 4.6 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PSC72033.1 - 3.7e-20 72.1 1.7 4.2e-12 46.3 0.4 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 PSC72033.1 - 6.2e-20 69.7 4.6 3.1e-05 23.3 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PSC72033.1 - 1.9e-18 64.8 6.1 0.0013 18.5 0.0 4.6 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 PSC72033.1 - 8.5e-13 47.9 2.7 2.8e-07 30.3 0.2 3.5 2 1 1 3 3 3 2 EF-hand domain pair Thioredoxin PF00085.20 PSC72033.1 - 5.4e-10 39.2 0.0 1.1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin EF-hand_9 PF14658.6 PSC72033.1 - 0.0019 18.4 0.6 4.3 7.7 0.0 3.0 3 0 0 3 3 3 2 EF-hand domain Thioredoxin_2 PF13098.6 PSC72033.1 - 0.0021 18.5 0.0 0.0063 16.9 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain TFIIA PF03153.13 PSC72033.1 - 0.0039 17.2 11.7 0.0058 16.7 11.7 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit EF-hand_4 PF12763.7 PSC72033.1 - 0.021 14.7 1.9 0.67 9.9 0.0 2.9 2 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand BAF1_ABF1 PF04684.13 PSC72033.1 - 0.023 13.7 2.5 0.032 13.3 2.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Presenilin PF01080.17 PSC72033.1 - 0.031 13.1 1.2 0.043 12.6 1.2 1.1 1 0 0 1 1 1 0 Presenilin HyaE PF07449.11 PSC72033.1 - 0.043 13.8 0.0 0.16 11.9 0.0 2.0 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE DDHD PF02862.17 PSC72033.1 - 0.043 14.0 0.5 0.065 13.4 0.5 1.3 1 0 0 1 1 1 0 DDHD domain Thioredoxin_8 PF13905.6 PSC72033.1 - 0.049 13.9 0.1 0.11 12.8 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin_7 PF13899.6 PSC72033.1 - 0.056 13.6 0.0 0.2 11.9 0.0 2.0 1 0 0 1 1 1 0 Thioredoxin-like FlgI PF02119.16 PSC72033.1 - 0.073 12.0 1.6 0.13 11.2 1.6 1.3 1 0 0 1 1 1 0 Flagellar P-ring protein Ndc1_Nup PF09531.10 PSC72033.1 - 0.091 11.4 0.2 0.1 11.3 0.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CPSF100_C PF13299.6 PSC72033.1 - 0.87 9.8 6.9 0.42 10.8 3.1 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal V_ATPase_I PF01496.19 PSC72033.1 - 1 7.2 3.4 1.4 6.7 3.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3464 PF11947.8 PSC72033.1 - 1.3 8.7 5.9 2.6 7.8 5.9 1.4 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF853 PF05872.12 PSC72033.1 - 4.2 5.8 12.8 3.7 6.0 0.0 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF853) UPF0560 PF10577.9 PSC72033.1 - 7.5 4.9 10.2 11 4.4 10.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4834 PF16118.5 PSC72033.1 - 8.1 7.5 10.7 18 6.4 10.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DNase_II PF03265.15 PSC72034.1 - 1.5e-34 119.8 0.0 2.3e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Deoxyribonuclease II CBM_20 PF00686.19 PSC72034.1 - 3.2e-20 71.8 0.0 6.7e-20 70.8 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain WD40 PF00400.32 PSC72035.1 - 3.2e-22 78.4 14.5 0.0013 19.5 0.1 6.5 6 1 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC72035.1 - 1.1e-08 35.2 4.7 0.013 15.8 0.0 4.5 2 2 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PPDFL PF15060.6 PSC72035.1 - 0.037 14.5 0.0 0.097 13.2 0.0 1.7 1 0 0 1 1 1 0 Differentiation and proliferation regulator Epimerase PF01370.21 PSC72036.1 - 1.3e-09 37.9 0.0 5.4e-06 26.1 0.0 2.4 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PSC72036.1 - 1.3e-07 31.7 0.0 3.5e-07 30.3 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 PSC72036.1 - 0.00073 19.0 0.0 0.05 13.0 0.0 2.1 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NmrA PF05368.13 PSC72036.1 - 0.00095 18.8 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family FAD_binding_7 PF03441.14 PSC72037.1 - 5.7e-49 166.3 0.1 5.7e-49 166.3 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase FAD_binding_4 PF01565.23 PSC72037.1 - 1.1e-10 41.4 1.0 1.1e-10 41.4 1.0 3.5 2 1 0 2 2 2 1 FAD binding domain ALO PF04030.14 PSC72037.1 - 3e-08 33.8 0.0 5.1e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase DNA_photolyase PF00875.18 PSC72037.1 - 1.8e-05 24.8 0.0 4.5e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 DNA photolyase DUF2722 PF10846.8 PSC72037.1 - 0.022 13.7 8.4 0.069 12.1 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) RPA43_OB PF17875.1 PSC72037.1 - 0.72 10.5 3.6 0.7 10.5 0.5 2.4 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I CCDC53 PF10152.9 PSC72037.1 - 1.2 9.5 4.5 3.4 8.1 0.3 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Kei1 PF08552.11 PSC72037.1 - 1.6 8.6 2.8 1.7 8.5 0.1 2.2 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Pex26 PF07163.12 PSC72037.1 - 4.3 6.5 5.8 8.7 5.6 0.0 2.2 2 0 0 2 2 2 0 Pex26 protein FAD_binding_7 PF03441.14 PSC72038.1 - 5.6e-49 166.4 0.1 5.6e-49 166.4 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain of DNA photolyase FAD_binding_4 PF01565.23 PSC72038.1 - 1.1e-10 41.4 1.0 1.1e-10 41.4 1.0 3.4 2 1 0 2 2 2 1 FAD binding domain ALO PF04030.14 PSC72038.1 - 2.9e-08 33.8 0.0 5e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase DNA_photolyase PF00875.18 PSC72038.1 - 1.8e-05 24.8 0.0 4.4e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 DNA photolyase DUF2722 PF10846.8 PSC72038.1 - 0.022 13.7 8.4 0.067 12.1 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) RPA43_OB PF17875.1 PSC72038.1 - 0.7 10.5 3.6 0.69 10.6 0.5 2.4 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I CCDC53 PF10152.9 PSC72038.1 - 1.1 9.6 4.5 3.3 8.1 0.3 2.5 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Kei1 PF08552.11 PSC72038.1 - 1.8 8.4 3.0 1.6 8.5 0.1 2.2 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 Pex26 PF07163.12 PSC72038.1 - 4.1 6.6 5.8 8.5 5.6 0.0 2.2 2 0 0 2 2 2 0 Pex26 protein Tubulin PF00091.25 PSC72040.1 - 2.6e-63 213.8 0.0 5.1e-63 212.9 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PSC72040.1 - 3.2e-41 140.4 0.1 5.4e-41 139.7 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain PP2C PF00481.21 PSC72040.1 - 1.3e-31 110.2 0.0 4.5e-30 105.1 0.0 2.4 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C_2 PF13672.6 PSC72040.1 - 5.3e-06 26.2 0.3 2.2e-05 24.2 0.3 2.0 1 1 0 1 1 1 1 Protein phosphatase 2C Tubulin_3 PF14881.6 PSC72040.1 - 0.0077 15.9 0.0 0.018 14.8 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Misat_Tub_SegII PF10644.9 PSC72040.1 - 0.0093 16.3 0.0 0.32 11.3 0.0 2.6 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 PSC72040.1 - 0.011 14.9 0.1 0.031 13.5 0.0 1.7 2 0 0 2 2 2 0 Tubulin like SpoIIE PF07228.12 PSC72040.1 - 0.02 14.8 0.3 1.1 9.2 0.0 2.4 2 0 0 2 2 2 0 Stage II sporulation protein E (SpoIIE) DUF2781 PF10914.8 PSC72041.1 - 6.2e-19 68.9 7.2 6.8e-19 68.7 7.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2781) PAP2 PF01569.21 PSC72042.1 - 9.7e-26 90.1 2.3 9.7e-26 90.1 2.3 1.7 2 1 0 2 2 2 1 PAP2 superfamily Arm PF00514.23 PSC72043.1 - 4.3e-29 99.6 26.8 8e-07 28.9 0.0 8.9 9 1 1 10 10 10 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 PSC72043.1 - 2e-06 28.1 26.6 0.0037 17.7 0.3 7.2 5 2 2 7 7 7 2 HEAT-like repeat HEAT_2 PF13646.6 PSC72043.1 - 0.00029 21.2 0.0 0.023 15.1 0.0 6.0 3 2 3 6 6 6 2 HEAT repeats Arm_3 PF16186.5 PSC72043.1 - 0.0019 17.7 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 Atypical Arm repeat HEAT PF02985.22 PSC72043.1 - 7.5 7.1 11.2 1.9 9.0 0.0 4.5 5 0 0 5 5 5 0 HEAT repeat Apolipoprotein PF01442.18 PSC72044.1 - 2.4e-08 34.1 4.1 0.0029 17.5 0.3 2.3 2 0 0 2 2 2 2 Apolipoprotein A1/A4/E domain Baculo_PEP_C PF04513.12 PSC72044.1 - 2.9e-08 33.9 17.8 0.00085 19.4 5.0 2.7 2 0 0 2 2 2 2 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1640 PF07798.11 PSC72044.1 - 8e-06 26.0 1.2 0.15 12.1 0.1 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1640) Flagellin_IN PF07196.13 PSC72044.1 - 2.5e-05 24.4 27.3 0.43 10.8 2.1 4.6 2 2 2 4 4 4 4 Flagellin hook IN motif DUF3606 PF12244.8 PSC72044.1 - 3.3e-05 23.7 8.0 0.91 9.5 0.1 5.1 4 2 2 6 6 6 2 Protein of unknown function (DUF3606) KxDL PF10241.9 PSC72044.1 - 4.5e-05 23.6 2.9 0.38 11.1 0.2 3.2 2 2 0 2 2 2 2 Uncharacterized conserved protein ApoLp-III PF07464.11 PSC72044.1 - 0.00016 21.8 4.0 0.31 11.1 0.3 2.5 2 0 0 2 2 2 2 Apolipophorin-III precursor (apoLp-III) OmpH PF03938.14 PSC72044.1 - 0.0008 19.8 0.6 1.7 9.0 0.1 2.2 2 0 0 2 2 2 2 Outer membrane protein (OmpH-like) Peptidase_M75 PF09375.10 PSC72044.1 - 0.0017 17.9 6.4 0.37 10.2 0.7 2.5 2 0 0 2 2 2 2 Imelysin Flg_hook PF02120.16 PSC72044.1 - 0.0065 16.3 8.6 2 8.3 0.5 3.7 2 2 2 4 4 4 4 Flagellar hook-length control protein FliK PalH PF08733.10 PSC72044.1 - 0.0076 15.3 1.2 2.5 7.0 0.1 2.1 2 0 0 2 2 2 2 PalH/RIM21 Itfg2 PF15907.5 PSC72044.1 - 0.017 14.2 0.0 33 3.4 0.0 3.1 3 0 0 3 3 3 0 Integrin-alpha FG-GAP repeat-containing protein 2 DUF948 PF06103.11 PSC72044.1 - 0.018 15.3 18.3 0.9 9.8 3.6 4.1 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) TolA_bind_tri PF16331.5 PSC72044.1 - 0.063 13.4 0.1 37 4.5 0.0 3.5 2 2 0 2 2 2 0 TolA binding protein trimerisation Ribosomal_S5 PF00333.20 PSC72044.1 - 0.085 12.9 4.5 41 4.2 0.1 3.7 3 0 0 3 3 3 0 Ribosomal protein S5, N-terminal domain MAJIN PF15077.6 PSC72044.1 - 0.097 12.4 0.0 1.1e+02 2.5 0.0 3.4 3 0 0 3 3 3 0 Membrane-anchored junction protein HTH_Mga PF08280.11 PSC72044.1 - 0.1 12.6 0.3 28 4.8 0.0 2.7 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) HTH domain ADIP PF11559.8 PSC72044.1 - 0.13 12.4 2.2 16 5.6 0.1 2.8 3 0 0 3 3 2 0 Afadin- and alpha -actinin-Binding OAF PF14941.6 PSC72044.1 - 0.14 11.6 1.4 12 5.2 0.1 2.2 2 0 0 2 2 2 0 Transcriptional regulator, Out at first Borrelia_REV PF03978.13 PSC72044.1 - 0.14 12.1 3.7 8.3 6.3 0.3 2.3 2 0 0 2 2 2 0 Borrelia burgdorferi REV protein Mannosyl_trans2 PF04188.13 PSC72044.1 - 0.15 11.4 1.9 10 5.3 0.1 2.1 2 0 0 2 2 2 0 Mannosyltransferase (PIG-V) DUF1043 PF06295.12 PSC72044.1 - 0.19 11.8 3.1 12 5.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1043) DUF3584 PF12128.8 PSC72044.1 - 0.23 8.9 0.2 10 3.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) FAM76 PF16046.5 PSC72044.1 - 0.36 10.1 2.4 13 5.1 0.2 2.1 2 0 0 2 2 2 0 FAM76 protein Neur_chan_LBD PF02931.23 PSC72044.1 - 0.38 10.2 0.4 1.1e+02 2.1 0.0 3.0 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel ligand binding domain NPV_P10 PF05531.12 PSC72044.1 - 0.52 10.8 4.4 90 3.6 0.1 4.2 2 2 0 4 4 4 0 Nucleopolyhedrovirus P10 protein Sec16_N PF12935.7 PSC72044.1 - 0.79 9.9 1.6 35 4.5 0.1 2.2 2 0 0 2 2 2 0 Vesicle coat trafficking protein Sec16 N-terminus DUF3672 PF12421.8 PSC72044.1 - 4.8 7.1 5.3 34 4.3 0.5 2.5 2 0 0 2 2 2 0 Fibronectin type III protein Mu-like_Pro PF10123.9 PSC72044.1 - 8.3 5.9 9.0 15 5.0 1.3 2.2 2 0 0 2 2 2 0 Mu-like prophage I protein Cu-oxidase_3 PF07732.15 PSC72045.1 - 1.4e-27 96.1 0.7 4.1e-13 49.4 0.2 4.7 4 0 0 4 4 4 4 Multicopper oxidase Cu-oxidase_2 PF07731.14 PSC72045.1 - 7.8e-21 74.3 17.2 5.5e-12 45.6 7.4 5.8 4 1 0 4 4 4 3 Multicopper oxidase Cu-oxidase PF00394.22 PSC72045.1 - 0.00035 20.7 0.0 0.17 12.0 0.0 3.3 3 0 0 3 3 3 1 Multicopper oxidase Copper-bind PF00127.20 PSC72045.1 - 0.0075 16.7 5.5 6.5 7.3 0.1 4.8 5 0 0 5 5 5 1 Copper binding proteins, plastocyanin/azurin family PKD PF00801.20 PSC72045.1 - 0.042 13.7 7.4 0.13 12.1 0.7 3.1 3 0 0 3 3 3 0 PKD domain F-box-like PF12937.7 PSC72046.1 - 1.5e-08 34.4 1.3 3.1e-08 33.4 1.3 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.7 PSC72046.1 - 3.9e-08 33.5 8.9 0.0024 18.2 0.2 5.1 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC72046.1 - 3.5e-05 23.5 17.1 0.0079 15.9 0.3 5.4 6 1 1 7 7 7 2 Leucine rich repeat Lipocalin_2 PF08212.12 PSC72046.1 - 0.0041 17.0 0.0 0.0083 16.1 0.0 1.5 1 0 0 1 1 1 1 Lipocalin-like domain F-box PF00646.33 PSC72046.1 - 0.022 14.6 0.2 0.063 13.2 0.2 1.8 1 0 0 1 1 1 0 F-box domain LRR_1 PF00560.33 PSC72046.1 - 0.035 14.6 5.3 49 5.1 0.1 5.6 5 0 0 5 5 5 0 Leucine Rich Repeat GST_N_2 PF13409.6 PSC72047.1 - 3.1e-16 59.4 0.0 7.6e-16 58.2 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PSC72047.1 - 1.9e-13 50.2 0.1 5.8e-13 48.7 0.1 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PSC72047.1 - 1.1e-08 35.2 0.1 1.9e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 PSC72047.1 - 0.00027 21.3 0.0 0.081 13.4 0.0 2.5 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 PSC72047.1 - 0.00037 20.7 0.0 0.00072 19.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 PSC72047.1 - 0.0041 16.9 0.0 0.0077 16.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain INT_SG_DDX_CT_C PF15300.6 PSC72047.1 - 0.031 14.1 0.0 0.74 9.7 0.0 2.2 2 0 0 2 2 2 0 INTS6/SAGE1/DDX26B/CT45 C-terminus K_trans PF02705.16 PSC72048.1 - 5e-176 586.4 20.1 5.9e-176 586.1 20.1 1.1 1 0 0 1 1 1 1 K+ potassium transporter GYF_2 PF14237.6 PSC72049.1 - 1.5e-09 37.5 0.0 5.7e-09 35.7 0.0 2.0 1 0 0 1 1 1 1 GYF domain 2 DnaJ PF00226.31 PSC72049.1 - 2.2e-06 27.7 0.0 4.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain GYF_2 PF14237.6 PSC72050.1 - 1.5e-09 37.5 0.0 5.7e-09 35.7 0.0 2.0 1 0 0 1 1 1 1 GYF domain 2 DnaJ PF00226.31 PSC72050.1 - 2.2e-06 27.7 0.0 4.3e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain PFU PF09070.11 PSC72051.1 - 0.02 15.2 0.0 0.038 14.3 0.0 1.4 1 0 0 1 1 1 0 PFU (PLAA family ubiquitin binding) Gpr1_Fun34_YaaH PF01184.19 PSC72052.1 - 1.5e-14 54.1 19.7 6.9e-11 42.1 13.6 2.3 1 1 1 2 2 2 2 GPR1/FUN34/yaaH family QCR10 PF09796.9 PSC72052.1 - 2.1 8.4 0.0 2.1 8.4 0.0 3.3 5 0 0 5 5 5 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) LRR_8 PF13855.6 PSC72053.1 - 2.7e-11 43.0 1.0 0.00025 20.7 0.0 2.9 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 PSC72053.1 - 2.8e-07 30.7 0.8 0.0006 20.2 0.0 2.9 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 PSC72053.1 - 9.1e-05 22.7 0.2 0.00017 21.8 0.2 1.5 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 PSC72053.1 - 0.00089 19.5 0.1 86 4.3 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat Podoplanin PF05808.11 PSC72053.1 - 0.1 12.7 0.6 0.29 11.2 0.6 1.9 1 1 0 1 1 1 0 Podoplanin VSP PF03302.13 PSC72053.1 - 0.13 11.1 0.2 0.27 10.1 0.2 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein LRR_6 PF13516.6 PSC72053.1 - 2.3 8.5 5.3 41 4.6 0.1 3.9 4 0 0 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.6 PSC72054.1 - 2.8e-11 43.0 1.0 0.00025 20.7 0.0 2.9 2 1 1 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 PSC72054.1 - 2.8e-07 30.7 0.8 0.0006 20.2 0.0 2.9 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRRNT_2 PF08263.12 PSC72054.1 - 9.1e-05 22.7 0.2 0.00017 21.8 0.2 1.5 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_1 PF00560.33 PSC72054.1 - 0.00089 19.5 0.1 86 4.3 0.0 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat Podoplanin PF05808.11 PSC72054.1 - 0.098 12.8 0.6 0.29 11.2 0.6 1.9 1 1 0 1 1 1 0 Podoplanin VSP PF03302.13 PSC72054.1 - 0.13 11.1 0.2 0.27 10.1 0.2 1.4 1 0 0 1 1 1 0 Giardia variant-specific surface protein LRR_6 PF13516.6 PSC72054.1 - 2.3 8.5 5.3 41 4.6 0.1 3.9 4 0 0 4 4 4 0 Leucine Rich repeat Polysacc_deac_1 PF01522.21 PSC72055.1 - 2.9e-08 33.6 0.0 5.3e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Sulfotransfer_2 PF03567.14 PSC72056.1 - 0.00016 21.7 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family Polyketide_cyc PF03364.20 PSC72057.1 - 6.6e-14 52.2 0.3 1.3e-13 51.2 0.3 1.5 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 PSC72057.1 - 2.4e-09 37.6 0.2 3.7e-09 37.0 0.2 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport SATase_N PF06426.14 PSC72058.1 - 0.077 13.4 0.0 0.1 13.0 0.0 1.1 1 0 0 1 1 1 0 Serine acetyltransferase, N-terminal DIL PF01843.19 PSC72058.1 - 0.12 12.7 0.1 0.13 12.6 0.1 1.1 1 0 0 1 1 1 0 DIL domain DUF2232 PF09991.9 PSC72058.1 - 0.13 11.5 0.1 0.14 11.3 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) PGM_PMM_I PF02878.16 PSC72059.1 - 5e-40 136.4 0.0 1e-39 135.4 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I Methyltr_RsmB-F PF01189.17 PSC72059.1 - 4e-27 95.2 0.0 9.2e-27 94.0 0.0 1.6 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F WD40 PF00400.32 PSC72059.1 - 1.9e-24 85.4 13.8 0.00023 21.9 0.2 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat PGM_PMM_II PF02879.16 PSC72059.1 - 4.4e-20 72.2 0.0 1.5e-19 70.5 0.0 2.0 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 PSC72059.1 - 3.7e-13 49.7 0.1 7.8e-13 48.6 0.1 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III ANAPC4_WD40 PF12894.7 PSC72059.1 - 3.3e-10 40.1 0.1 0.1 12.9 0.0 5.9 4 2 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PSC72059.1 - 0.0032 16.5 0.1 0.6 9.0 0.0 2.6 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 PSC72059.1 - 0.01 15.8 1.5 2.7 8.0 0.1 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat FtsJ PF01728.19 PSC72059.1 - 0.17 12.0 0.0 0.46 10.6 0.0 1.7 2 0 0 2 2 2 0 FtsJ-like methyltransferase IKI3 PF04762.12 PSC72059.1 - 0.19 9.7 0.1 11 3.9 0.0 2.1 2 0 0 2 2 2 0 IKI3 family CENP-T_C PF15511.6 PSC72060.1 - 2e-08 34.3 0.1 2.5e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PSC72060.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 PSC72060.1 - 0.00022 21.3 0.1 0.00031 20.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 PSC72060.1 - 0.0011 18.9 0.1 0.0017 18.4 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 PSC72060.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PSC72060.1 - 0.0015 18.9 0.1 0.0017 18.8 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 PSC72060.1 - 0.033 14.3 0.0 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Transketolase_N PF00456.21 PSC72061.1 - 3.9e-150 499.4 0.2 5.4e-150 499.0 0.2 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 PSC72061.1 - 7.5e-40 136.5 0.0 1.2e-39 135.8 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 PSC72061.1 - 1.5e-12 47.5 0.0 4.1e-12 46.1 0.0 1.7 1 0 0 1 1 1 1 Transketolase, C-terminal domain E1_dh PF00676.20 PSC72061.1 - 0.016 14.1 0.0 0.026 13.5 0.0 1.2 1 0 0 1 1 1 0 Dehydrogenase E1 component DXP_synthase_N PF13292.6 PSC72061.1 - 0.028 13.6 0.1 0.06 12.5 0.0 1.7 2 0 0 2 2 2 0 1-deoxy-D-xylulose-5-phosphate synthase DUF498 PF04430.14 PSC72061.1 - 0.071 13.2 0.0 0.3 11.2 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF498/DUF598) PAP_fibrillin PF04755.12 PSC72062.1 - 3.6e-22 79.3 0.0 5.6e-20 72.1 0.0 2.0 1 1 0 1 1 1 1 PAP_fibrillin tRNA_int_endo PF01974.17 PSC72063.1 - 5.8e-24 84.0 0.0 1.2e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Lactamase_B_2 PF12706.7 PSC72063.1 - 3.5e-13 49.5 0.1 7.8e-13 48.4 0.1 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RMMBL PF07521.12 PSC72063.1 - 7.3e-12 45.1 0.2 5.9e-10 38.9 0.0 2.9 3 0 0 3 3 3 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 PSC72063.1 - 3.2e-09 37.1 0.1 1.1e-08 35.3 0.1 2.0 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_3 PF13483.6 PSC72063.1 - 0.0011 18.9 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain TilS PF09179.11 PSC72063.1 - 1.1 9.8 5.7 3.5 8.2 0.8 3.5 3 0 0 3 3 3 0 TilS substrate binding domain GRAM PF02893.20 PSC72064.1 - 0.064 13.1 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 GRAM domain NIF PF03031.18 PSC72065.1 - 1.6e-19 70.2 0.1 2.3e-19 69.7 0.1 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase COX17 PF05051.13 PSC72066.1 - 4.7e-21 74.9 5.1 5.9e-21 74.6 5.1 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) Tyr-DNA_phospho PF06087.12 PSC72067.1 - 1.1e-42 146.5 0.0 8.5e-28 97.4 0.0 2.1 1 1 1 2 2 2 2 Tyrosyl-DNA phosphodiesterase DUF1917 PF08939.10 PSC72067.1 - 2e-13 50.9 0.0 3e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) PLDc_2 PF13091.6 PSC72067.1 - 0.055 13.4 0.0 1.9 8.4 0.0 2.2 2 0 0 2 2 2 0 PLD-like domain Suf PF05843.14 PSC72068.1 - 0.0033 17.4 3.8 0.0045 17.0 3.8 1.1 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) DUF2722 PF10846.8 PSC72068.1 - 0.0058 15.6 4.5 0.0058 15.6 4.5 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 PSC72068.1 - 0.013 15.6 11.2 0.014 15.4 11.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 PSC72068.1 - 0.016 14.8 10.8 0.02 14.5 10.8 1.1 1 0 0 1 1 1 0 Spt20 family DUF2681 PF10883.8 PSC72068.1 - 0.33 11.4 10.8 0.7 10.3 10.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) TERB2 PF15101.6 PSC72068.1 - 0.37 10.8 3.8 0.56 10.2 3.8 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 ABC_membrane_2 PF06472.15 PSC72069.1 - 6.2e-62 209.4 0.3 8.4e-62 209.0 0.3 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 PSC72069.1 - 8e-18 65.3 0.0 1.6e-17 64.3 0.0 1.6 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 PSC72069.1 - 0.011 15.2 0.0 0.24 10.8 0.0 2.3 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 PSC72069.1 - 0.014 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 PSC72069.1 - 0.023 14.4 0.0 0.11 12.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 PSC72069.1 - 0.041 13.6 0.0 0.092 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 PSC72069.1 - 0.093 13.2 0.2 0.19 12.2 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 PSC72069.1 - 0.093 13.1 1.4 0.22 11.9 0.0 2.4 2 2 0 2 2 2 0 AAA ATPase domain Choline_transpo PF04515.12 PSC72070.1 - 8.4e-58 196.1 21.2 8.4e-58 196.1 21.2 1.8 3 0 0 3 3 3 1 Plasma-membrane choline transporter MPDZ_u10 PF16667.5 PSC72070.1 - 0.1 13.5 0.6 0.21 12.5 0.6 1.5 1 0 0 1 1 1 0 Unstructured region 10 on multiple PDZ protein Histone_H2A_C PF16211.5 PSC72071.1 - 1.5e-20 72.6 2.1 3.3e-20 71.5 2.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 PSC72071.1 - 3.7e-15 56.5 0.0 4.6e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC72071.1 - 1e-05 25.7 0.0 1.6e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3506 PF12014.8 PSC72072.1 - 2.9e-05 24.1 0.1 0.00024 21.1 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) DUF3506 PF12014.8 PSC72073.1 - 2.9e-05 24.1 0.1 0.00024 21.1 0.1 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) Barwin PF00967.17 PSC72074.1 - 2.9e-30 104.5 0.4 7.5e-30 103.2 0.4 1.7 1 0 0 1 1 1 1 Barwin family GAGA_bind PF06217.12 PSC72074.1 - 1 9.6 12.3 1.4 9.1 12.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family TFIIA PF03153.13 PSC72074.1 - 6.8 6.6 25.3 9.3 6.1 25.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FF PF01846.19 PSC72075.1 - 6.4e-35 119.1 5.9 6.2e-10 39.1 0.0 5.6 5 0 0 5 5 5 4 FF domain WW PF00397.26 PSC72075.1 - 1.5e-10 40.9 14.2 1.7e-07 31.2 0.5 3.1 3 0 0 3 3 3 2 WW domain Glyco_hyd_101C PF17451.2 PSC72075.1 - 2.7e-05 24.4 2.6 0.094 13.0 0.2 2.5 2 0 0 2 2 2 2 Glycosyl hydrolase 101 beta sandwich domain DUF4355 PF14265.6 PSC72075.1 - 0.002 18.4 4.7 0.0078 16.4 4.7 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4355) PCMT PF01135.19 PSC72076.1 - 4.4e-34 118.1 0.0 8.5e-34 117.1 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) BTB PF00651.31 PSC72076.1 - 7.9e-10 38.9 0.0 2e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain DOT1 PF08123.13 PSC72076.1 - 0.0045 16.5 0.0 0.008 15.7 0.0 1.3 1 0 0 1 1 1 1 Histone methylation protein DOT1 BACK PF07707.15 PSC72076.1 - 0.0064 16.6 0.1 0.2 11.8 0.1 2.6 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF4061 PF13270.6 PSC72076.1 - 0.042 14.2 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) Ubie_methyltran PF01209.18 PSC72076.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family PrmA PF06325.13 PSC72076.1 - 0.15 11.5 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) TPR_2 PF07719.17 PSC72077.1 - 0.00067 19.6 8.1 0.29 11.3 0.3 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_9 PF13371.6 PSC72077.1 - 0.018 15.2 19.6 0.091 12.9 4.9 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat HflK_N PF12221.8 PSC72077.1 - 0.12 12.4 1.4 0.13 12.3 0.1 1.7 2 0 0 2 2 2 0 Bacterial membrane protein N terminal TPR_1 PF00515.28 PSC72077.1 - 0.34 10.8 6.3 2.4 8.1 1.4 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 PSC72077.1 - 1.2 9.6 7.1 2.6 8.5 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Gly_transf_sug PF04488.15 PSC72078.1 - 5e-22 78.4 0.0 9.6e-22 77.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif TcdA_TcdB PF12919.7 PSC72078.1 - 0.37 10.0 2.9 0.67 9.2 0.2 2.0 2 0 0 2 2 2 0 TcdA/TcdB catalytic glycosyltransferase domain Polysacc_synt_4 PF04669.13 PSC72079.1 - 1.3e-23 83.5 0.0 2e-22 79.7 0.0 2.1 1 1 0 1 1 1 1 Polysaccharide biosynthesis Histone_H2A_C PF16211.5 PSC72080.1 - 1.6e-20 72.5 2.1 3.3e-20 71.5 2.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 PSC72080.1 - 1.8e-15 57.4 0.0 2.3e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC72080.1 - 1.5e-05 25.1 0.0 2.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SET PF00856.28 PSC72082.1 - 2.2e-19 70.5 0.0 2.2e-19 70.5 0.0 3.7 5 0 0 5 5 5 1 SET domain AWS PF17907.1 PSC72082.1 - 3.7e-11 42.9 5.4 8.1e-11 41.8 5.4 1.6 1 0 0 1 1 1 1 AWS domain PWWP PF00855.17 PSC72082.1 - 6.9e-11 42.4 0.0 6.9e-11 42.4 0.0 2.5 2 0 0 2 2 2 1 PWWP domain GATA PF00320.27 PSC72082.1 - 3.8e-09 36.0 4.7 7.3e-09 35.1 4.7 1.5 1 0 0 1 1 1 1 GATA zinc finger B3 PF02362.21 PSC72082.1 - 5.3e-06 26.2 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 B3 DNA binding domain Tudor_2 PF18104.1 PSC72082.1 - 0.0014 18.3 0.2 0.0027 17.4 0.2 1.4 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain Tudor_3 PF18115.1 PSC72082.1 - 0.0067 16.2 0.8 0.02 14.8 0.8 1.7 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain SET PF00856.28 PSC72083.1 - 2.2e-19 70.5 0.0 2.2e-19 70.5 0.0 3.7 5 0 0 5 5 5 1 SET domain AWS PF17907.1 PSC72083.1 - 3.7e-11 42.9 5.4 8.1e-11 41.8 5.4 1.6 1 0 0 1 1 1 1 AWS domain PWWP PF00855.17 PSC72083.1 - 6.9e-11 42.4 0.0 6.9e-11 42.4 0.0 2.5 2 0 0 2 2 2 1 PWWP domain GATA PF00320.27 PSC72083.1 - 3.8e-09 36.0 4.7 7.3e-09 35.1 4.7 1.5 1 0 0 1 1 1 1 GATA zinc finger B3 PF02362.21 PSC72083.1 - 7.3e-07 29.0 0.0 1.4e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 B3 DNA binding domain Tudor_2 PF18104.1 PSC72083.1 - 0.0014 18.3 0.2 0.0027 17.4 0.2 1.4 1 0 0 1 1 1 1 Jumonji domain-containing protein 2A Tudor domain Tudor_3 PF18115.1 PSC72083.1 - 0.0067 16.2 0.8 0.02 14.8 0.8 1.7 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF563 PF04577.14 PSC72084.1 - 2.4e-22 80.1 0.6 5.1e-22 79.0 0.6 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF563) DUF5473 PF17567.2 PSC72084.1 - 0.11 12.8 1.6 0.28 11.5 1.6 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5473) tRNA-synt_1c PF00749.21 PSC72085.1 - 1.1e-104 349.8 0.0 1.5e-104 349.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain TPR_1 PF00515.28 PSC72085.1 - 2.5e-80 261.3 49.0 5.4e-07 29.2 0.0 15.4 15 0 0 15 15 15 14 Tetratricopeptide repeat TPR_2 PF07719.17 PSC72085.1 - 5.3e-71 229.1 74.6 5.5e-06 26.1 0.0 15.9 16 0 0 16 16 15 15 Tetratricopeptide repeat TPR_11 PF13414.6 PSC72085.1 - 1.8e-66 219.5 55.8 2.6e-07 30.2 0.5 15.6 4 3 11 15 15 15 14 TPR repeat TPR_8 PF13181.6 PSC72085.1 - 2e-48 158.6 33.5 0.0035 17.4 0.0 15.8 15 0 0 15 15 15 11 Tetratricopeptide repeat TPR_17 PF13431.6 PSC72085.1 - 5.5e-42 139.2 39.7 2.3e-05 24.5 0.1 15.0 15 0 0 15 15 15 9 Tetratricopeptide repeat TPR_9 PF13371.6 PSC72085.1 - 4.2e-41 138.9 69.8 2.7e-06 27.4 0.2 13.2 4 3 8 13 13 13 12 Tetratricopeptide repeat TPR_16 PF13432.6 PSC72085.1 - 9e-38 128.7 121.0 8.2e-09 36.0 2.2 11.8 6 2 7 14 14 13 11 Tetratricopeptide repeat TPR_12 PF13424.6 PSC72085.1 - 1.5e-24 86.1 76.1 1.2e-07 31.9 2.1 10.9 6 3 5 11 11 11 8 Tetratricopeptide repeat TPR_14 PF13428.6 PSC72085.1 - 5.9e-20 70.2 90.9 0.00089 19.9 1.9 17.4 4 2 15 19 19 17 7 Tetratricopeptide repeat TPR_7 PF13176.6 PSC72085.1 - 1.2e-19 68.8 38.8 0.019 15.0 0.0 13.3 14 0 0 14 14 14 5 Tetratricopeptide repeat TPR_19 PF14559.6 PSC72085.1 - 8e-18 64.7 65.3 0.00049 20.6 5.1 10.8 7 5 5 12 12 11 7 Tetratricopeptide repeat TPR_6 PF13174.6 PSC72085.1 - 4.4e-14 52.1 51.3 0.089 13.5 0.1 14.5 15 0 0 15 15 15 4 Tetratricopeptide repeat ANAPC3 PF12895.7 PSC72085.1 - 1.7e-08 34.6 29.7 0.00017 21.7 0.2 7.1 5 3 3 8 8 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 PSC72085.1 - 4.3e-07 29.6 61.6 0.49 10.3 0.0 12.7 13 0 0 13 13 13 5 Tetratricopeptide repeat BTAD PF03704.17 PSC72085.1 - 1.4e-05 25.5 44.8 8.5e-05 23.0 5.3 7.9 3 1 5 8 8 8 2 Bacterial transcriptional activator domain SHNi-TPR PF10516.9 PSC72085.1 - 6.7e-05 22.3 28.6 0.86 9.1 0.0 10.2 12 0 0 12 12 12 2 SHNi-TPR Fis1_TPR_C PF14853.6 PSC72085.1 - 0.0023 17.9 18.3 2.8 8.1 0.0 7.9 6 3 2 9 9 7 2 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.6 PSC72085.1 - 0.0037 16.5 28.6 0.023 13.9 4.0 6.7 3 2 2 6 6 6 2 Tetratricopeptide repeat NARP1 PF12569.8 PSC72085.1 - 0.0047 15.9 8.6 0.84 8.5 0.1 4.6 3 2 2 5 5 5 2 NMDA receptor-regulated protein 1 DUF3856 PF12968.7 PSC72085.1 - 0.0058 16.7 22.3 2.1 8.4 0.0 7.2 5 3 3 8 8 8 2 Domain of Unknown Function (DUF3856) Coatomer_E PF04733.14 PSC72085.1 - 0.013 15.0 0.9 6.9 6.0 0.1 3.1 2 1 0 3 3 3 0 Coatomer epsilon subunit TPR_5 PF12688.7 PSC72085.1 - 0.091 13.0 26.4 0.12 12.7 1.6 6.6 4 2 2 7 7 6 0 Tetratrico peptide repeat TPR_4 PF07721.14 PSC72085.1 - 0.12 13.1 0.0 0.12 13.1 0.0 14.5 15 0 0 15 15 13 0 Tetratricopeptide repeat SMG1 PF15785.5 PSC72085.1 - 0.59 8.4 3.3 2.5 6.4 0.7 2.5 2 1 0 2 2 2 0 Serine/threonine-protein kinase smg-1 DUF627 PF04781.12 PSC72085.1 - 0.63 10.1 3.0 1.6 8.8 0.1 3.3 4 0 0 4 4 2 0 Protein of unknown function (DUF627) VPS28 PF03997.12 PSC72086.1 - 5.8e-61 205.5 0.0 6.9e-61 205.2 0.0 1.0 1 0 0 1 1 1 1 VPS28 protein Se-cys_synth_N PF12390.8 PSC72086.1 - 0.17 12.1 0.0 0.59 10.4 0.0 2.0 1 0 0 1 1 1 0 Selenocysteine synthase N terminal SOUL PF04832.12 PSC72087.1 - 7.5e-37 127.1 0.1 8.8e-37 126.9 0.1 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein DUF2135 PF09906.9 PSC72087.1 - 0.093 13.1 0.1 0.23 11.8 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2135) RRM_1 PF00076.22 PSC72088.1 - 2.7e-32 110.4 0.0 1.1e-16 60.4 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PSC72088.1 - 1.2e-06 28.6 0.0 0.0052 16.9 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif Transformer PF06495.11 PSC72088.1 - 0.025 14.7 18.9 0.043 13.9 18.9 1.4 1 0 0 1 1 1 0 Fruit fly transformer protein RRM_occluded PF16842.5 PSC72088.1 - 0.031 14.1 0.0 0.57 10.1 0.0 2.8 3 0 0 3 3 3 0 Occluded RNA-recognition motif CDC45 PF02724.14 PSC72088.1 - 2.5 6.3 5.3 3.2 5.9 5.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Rrn6 PF10214.9 PSC72088.1 - 5.2 5.4 11.8 7.1 5.0 11.8 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Cation_ATPase_C PF00689.21 PSC72089.1 - 7.6e-45 152.9 0.3 7.6e-45 152.9 0.3 2.2 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 PSC72089.1 - 5.3e-39 133.6 0.6 5.3e-39 133.6 0.6 2.9 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 PSC72089.1 - 4.3e-17 62.0 0.0 9.1e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 PSC72089.1 - 5.7e-17 62.7 2.8 2.3e-16 60.7 2.8 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PSC72089.1 - 1.9e-11 43.5 0.0 4.6e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PSC72089.1 - 1.9e-05 24.6 1.4 0.00022 21.1 0.7 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pyr_redox_2 PF07992.14 PSC72090.1 - 0.00019 20.8 0.1 0.52 9.5 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PSC72090.1 - 0.0002 21.5 0.6 0.0002 21.5 0.6 3.2 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Trp_halogenase PF04820.14 PSC72090.1 - 0.00059 18.8 0.4 0.0026 16.7 0.0 2.0 2 0 0 2 2 2 1 Tryptophan halogenase IBN_N PF03810.19 PSC72090.1 - 0.0015 18.4 0.1 0.0047 16.8 0.0 1.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain Importin_rep_3 PF18806.1 PSC72090.1 - 0.11 12.6 0.0 0.34 11.0 0.0 1.8 1 0 0 1 1 1 0 Importin 13 repeat Lycopene_cycl PF05834.12 PSC72090.1 - 0.13 11.3 2.5 0.45 9.5 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 PSC72090.1 - 0.29 10.2 1.2 5.2 6.1 0.0 2.4 2 0 0 2 2 2 0 Glucose inhibited division protein A PRKCSH PF07915.13 PSC72091.1 - 1.3e-13 51.7 4.8 2.7e-13 50.7 4.8 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 PSC72091.1 - 3.9e-07 29.9 0.1 6.5e-07 29.2 0.1 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 PSC72092.1 - 1.3e-13 51.8 4.8 2.7e-13 50.7 4.8 1.6 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein PRKCSH_1 PF13015.6 PSC72092.1 - 3.5e-07 30.0 0.1 5.8e-07 29.3 0.1 1.3 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Raf1_N PF18578.1 PSC72093.1 - 3.3e-30 104.7 1.2 6e-30 103.9 1.2 1.5 1 0 0 1 1 1 1 Rubisco accumulation factor 1 alpha helical domain RuBisCo_chap_C PF18087.1 PSC72093.1 - 1.2e-21 76.8 0.1 1.8e-21 76.2 0.1 1.3 1 0 0 1 1 1 1 Rubisco Assembly chaperone C-terminal domain Raf1_HTH PF18579.1 PSC72093.1 - 3.1e-20 71.6 0.3 5.3e-20 70.9 0.3 1.4 1 0 0 1 1 1 1 Rubisco accumulation factor 1 helix turn helix domain Hira PF07569.11 PSC72094.1 - 5.1e-40 137.6 0.0 1.6e-39 136.0 0.0 1.8 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 PSC72094.1 - 6.4e-28 96.4 24.4 1.8e-06 28.6 2.0 7.8 8 1 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC72094.1 - 6.5e-18 64.8 0.0 6.4e-05 23.2 0.0 6.4 4 2 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PSC72094.1 - 0.00047 19.2 2.5 0.89 8.4 0.0 4.1 4 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PSC72094.1 - 0.0045 16.9 0.3 2 8.2 0.0 3.2 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 PSC72094.1 - 0.01 15.8 5.5 7.8 6.6 0.1 4.6 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat TFIIIC_delta PF12657.7 PSC72094.1 - 0.19 11.6 0.7 6.2 6.7 0.0 2.6 2 1 0 2 2 2 0 Transcription factor IIIC subunit delta N-term EF-hand_7 PF13499.6 PSC72095.1 - 2.5e-14 53.5 0.1 4.1e-11 43.2 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PSC72095.1 - 5.1e-09 35.9 0.1 1.8e-08 34.1 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain pair Rhodanese PF00581.20 PSC72095.1 - 2.2e-08 34.6 0.0 8.5e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain EF-hand_1 PF00036.32 PSC72095.1 - 5.6e-08 31.8 0.0 0.019 14.5 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 PSC72095.1 - 9.8e-05 22.0 0.0 0.017 15.0 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 PSC72095.1 - 0.087 12.4 0.1 0.31 10.6 0.0 2.0 3 0 0 3 3 3 0 EF hand EF-hand_7 PF13499.6 PSC72096.1 - 2.5e-14 53.5 0.1 4.1e-11 43.2 0.1 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PSC72096.1 - 5.1e-09 35.9 0.1 1.8e-08 34.1 0.1 2.0 1 1 1 2 2 2 1 EF-hand domain pair Rhodanese PF00581.20 PSC72096.1 - 2.2e-08 34.6 0.0 8.5e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 Rhodanese-like domain EF-hand_1 PF00036.32 PSC72096.1 - 5.6e-08 31.8 0.0 0.019 14.5 0.0 2.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 PSC72096.1 - 9.8e-05 22.0 0.0 0.017 15.0 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 PSC72096.1 - 0.087 12.4 0.1 0.31 10.6 0.0 2.0 3 0 0 3 3 3 0 EF hand AAA PF00004.29 PSC72097.1 - 3.4e-49 166.7 0.0 5.5e-39 133.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) PEX-1N PF09262.11 PSC72097.1 - 7.8e-24 83.9 0.3 1.8e-23 82.7 0.2 1.7 2 0 0 2 2 1 1 Peroxisome biogenesis factor 1, N-terminal AAA_16 PF13191.6 PSC72097.1 - 1.8e-09 38.2 16.1 7.3e-05 23.2 0.4 4.9 4 2 1 5 5 3 2 AAA ATPase domain AAA_lid_3 PF17862.1 PSC72097.1 - 5.8e-09 35.6 12.1 5.2e-07 29.4 0.1 4.1 4 0 0 4 4 4 2 AAA+ lid domain NACHT PF05729.12 PSC72097.1 - 3.3e-08 33.6 0.0 0.0014 18.6 0.0 3.5 2 1 1 3 3 3 1 NACHT domain IstB_IS21 PF01695.17 PSC72097.1 - 5.9e-08 32.7 0.0 0.0087 15.8 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_5 PF07728.14 PSC72097.1 - 1.8e-06 28.0 0.0 0.012 15.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 PSC72097.1 - 6.3e-06 26.4 0.0 0.028 14.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 PSC72097.1 - 6.8e-06 26.4 2.7 0.018 15.3 0.2 3.5 2 2 1 3 3 3 2 AAA domain AAA_29 PF13555.6 PSC72097.1 - 2.1e-05 24.2 0.0 0.0085 15.8 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain T2SSE PF00437.20 PSC72097.1 - 0.00013 21.1 0.0 0.0079 15.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 PSC72097.1 - 0.00016 21.3 4.9 1.4 8.4 0.1 3.7 2 1 0 3 3 3 2 AAA domain AAA_7 PF12775.7 PSC72097.1 - 0.00075 19.1 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_28 PF13521.6 PSC72097.1 - 0.0008 19.7 0.0 0.34 11.2 0.0 2.8 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 PSC72097.1 - 0.0011 18.2 0.2 0.96 8.7 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin Bac_DnaA PF00308.18 PSC72097.1 - 0.0019 18.1 0.0 0.21 11.4 0.0 2.3 2 0 0 2 2 2 1 Bacterial dnaA protein RuvB_N PF05496.12 PSC72097.1 - 0.0021 17.8 0.6 0.017 14.9 0.0 2.6 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 PSC72097.1 - 0.0024 18.2 0.0 1.7 9.0 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_23 PF13476.6 PSC72097.1 - 0.0028 18.2 0.0 0.16 12.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain UFD1 PF03152.14 PSC72097.1 - 0.0066 16.0 0.0 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 TsaE PF02367.17 PSC72097.1 - 0.0073 16.3 0.0 0.092 12.8 0.0 2.1 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase_2 PF01637.18 PSC72097.1 - 0.012 15.6 0.0 5.2 6.9 0.0 2.2 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_19 PF13245.6 PSC72097.1 - 0.014 15.7 1.1 1 9.7 0.2 2.5 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 PSC72097.1 - 0.02 14.8 0.0 1.9 8.3 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain Mg_chelatase PF01078.21 PSC72097.1 - 0.024 14.0 0.2 3.4 7.0 0.0 2.3 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 PSC72097.1 - 0.032 14.8 1.2 4.4 7.8 0.1 3.1 3 1 0 3 3 3 0 ABC transporter AAA_18 PF13238.6 PSC72097.1 - 0.033 14.7 0.1 7.6 7.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 PSC72097.1 - 0.036 13.2 0.0 6 5.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) TniB PF05621.11 PSC72097.1 - 0.071 12.5 0.0 11 5.4 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_11 PF13086.6 PSC72097.1 - 0.083 12.7 0.0 0.48 10.2 0.0 2.0 2 0 0 2 2 2 0 AAA domain AFG1_ATPase PF03969.16 PSC72097.1 - 0.12 11.2 0.0 2.6 6.8 0.0 2.1 2 0 0 2 2 2 0 AFG1-like ATPase AAA_24 PF13479.6 PSC72097.1 - 0.16 11.7 0.1 1.6 8.4 0.1 2.1 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 PSC72097.1 - 0.22 10.9 1.0 16 4.9 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein Histone_H2A_C PF16211.5 PSC72098.1 - 1.6e-20 72.5 2.1 3.3e-20 71.5 2.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 PSC72098.1 - 1.4e-15 57.9 0.0 1.7e-15 57.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC72098.1 - 1.5e-05 25.2 0.0 2.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SAM_2 PF07647.17 PSC72099.1 - 1.9e-06 27.9 0.0 8.8e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PSC72099.1 - 2.7e-05 24.5 0.0 5.6e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DEC-1_N PF04625.13 PSC72099.1 - 3.8e-05 22.9 14.4 6.6e-05 22.1 14.4 1.5 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region SAM_PNT PF02198.16 PSC72099.1 - 0.00039 20.3 0.0 0.00074 19.4 0.0 1.5 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Spc7 PF08317.11 PSC72099.1 - 0.14 11.0 13.4 0.08 11.8 3.7 2.3 1 1 0 2 2 2 0 Spc7 kinetochore protein AAA_13 PF13166.6 PSC72099.1 - 0.18 10.4 2.4 5.4 5.5 2.2 2.2 2 0 0 2 2 2 0 AAA domain YkyA PF10368.9 PSC72099.1 - 0.45 10.2 3.6 6.2 6.5 0.6 2.2 2 0 0 2 2 2 0 Putative cell-wall binding lipoprotein E2R135 PF11570.8 PSC72099.1 - 1 9.7 6.6 25 5.2 6.5 2.6 1 1 0 1 1 1 0 Coiled-coil receptor-binding R-domain of colicin E2 ABC_tran_CTD PF16326.5 PSC72099.1 - 2.2 8.6 15.8 0.2 12.0 6.0 3.1 2 1 0 2 2 2 0 ABC transporter C-terminal domain GAS PF13851.6 PSC72099.1 - 2.3 7.5 7.3 8.2 5.7 7.0 2.1 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding DUF5082 PF16888.5 PSC72099.1 - 3.4 7.9 9.6 0.68 10.2 0.2 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) Filament PF00038.21 PSC72099.1 - 7.7 6.0 7.9 1.1 8.8 2.2 2.2 2 1 1 3 3 3 0 Intermediate filament protein ATG16 PF08614.11 PSC72099.1 - 8.2 6.6 21.4 3.7e+02 1.2 19.9 3.0 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) EphA2_TM PF14575.6 PSC72100.1 - 2.9 8.8 0.0 2.9 8.8 0.0 3.4 2 1 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TFIIA PF03153.13 PSC72100.1 - 8.3 6.3 37.2 8.1 6.3 31.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit adh_short_C2 PF13561.6 PSC72101.1 - 1.5e-44 152.3 0.3 1.6e-44 152.2 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PSC72101.1 - 1e-26 93.6 0.1 1.2e-26 93.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Presenilin PF01080.17 PSC72102.1 - 0.024 13.4 4.3 0.034 12.9 4.3 1.2 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 PSC72102.1 - 0.046 14.4 23.5 0.12 13.0 6.5 3.3 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RLL PF10036.9 PSC72102.1 - 0.09 12.6 10.3 0.34 10.7 10.3 2.0 1 1 0 1 1 1 0 RNA transcription, translation and transport factor protein DUF2722 PF10846.8 PSC72102.1 - 0.16 10.9 19.7 0.094 11.6 11.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Fmp27_SW PF10305.9 PSC72102.1 - 0.37 11.5 3.9 12 6.7 1.9 2.5 2 0 0 2 2 2 0 RNA pol II promoter Fmp27 protein domain Roughex PF06020.11 PSC72102.1 - 0.74 8.9 11.4 0.16 11.1 1.3 2.3 2 0 0 2 2 2 0 Drosophila roughex protein CPSF100_C PF13299.6 PSC72102.1 - 1.7 8.8 7.2 1.2 9.3 1.7 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal EPL1 PF10513.9 PSC72102.1 - 5.2 7.4 11.3 31 4.9 6.6 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like MFMR_assoc PF16596.5 PSC72102.1 - 8.5 6.8 12.3 0.99 9.9 3.1 2.5 2 0 0 2 2 2 0 Disordered region downstream of MFMR PHD_3 PF13922.6 PSC72102.1 - 9.5 6.7 11.8 6.8 7.2 0.3 3.0 2 0 0 2 2 2 0 PHD domain of transcriptional enhancer, Asx Pro_isomerase PF00160.21 PSC72104.1 - 5.6e-47 159.9 0.0 7.7e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TAT_signal PF10518.9 PSC72104.1 - 0.0081 16.0 5.5 0.019 14.8 5.5 1.6 1 0 0 1 1 1 1 TAT (twin-arginine translocation) pathway signal sequence DUF1525 PF07511.11 PSC72104.1 - 0.058 13.5 3.2 0.63 10.2 3.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1525) Thioredoxin_3 PF13192.6 PSC72104.1 - 0.22 11.6 0.0 0.41 10.7 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain RNA_pol_Rpb5_C PF01191.19 PSC72105.1 - 8.3e-32 108.9 0.0 1.9e-31 107.7 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 PSC72105.1 - 4.1e-17 62.5 0.1 3.4e-16 59.6 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain TPR_14 PF13428.6 PSC72105.1 - 9.1e-13 47.9 24.6 1.3 10.0 0.0 11.2 10 3 2 12 12 10 4 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PSC72105.1 - 1.7e-10 40.9 5.0 0.6 10.1 0.0 6.8 7 1 0 7 7 7 3 Mad3/BUB1 homology region 1 Suf PF05843.14 PSC72105.1 - 4.1e-10 40.1 6.5 0.074 13.0 0.0 5.7 5 1 0 5 5 5 3 Suppressor of forked protein (Suf) TPR_15 PF13429.6 PSC72105.1 - 6.5e-10 38.7 1.5 3.2e-05 23.3 0.1 4.3 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 PSC72105.1 - 3.2e-08 33.1 10.0 2.6 8.4 0.0 8.5 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_12 PF13424.6 PSC72105.1 - 5.4e-08 33.0 0.2 0.071 13.4 0.0 5.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 PSC72105.1 - 7.7e-06 25.7 0.3 18 5.9 0.0 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat NRDE-2 PF08424.10 PSC72105.1 - 0.00018 20.7 6.0 5.8 5.9 0.1 5.7 4 2 1 6 6 6 2 NRDE-2, necessary for RNA interference Mrr_cat PF04471.12 PSC72105.1 - 0.0074 16.3 0.0 0.044 13.8 0.0 2.3 2 0 0 2 2 2 1 Restriction endonuclease CKAP2_C PF15297.6 PSC72105.1 - 0.0094 15.1 0.0 0.42 9.7 0.0 2.2 2 0 0 2 2 2 1 Cytoskeleton-associated protein 2 C-terminus SNAP PF14938.6 PSC72105.1 - 0.012 15.0 0.3 2.9 7.3 0.0 3.4 4 0 0 4 4 4 0 Soluble NSF attachment protein, SNAP PPR PF01535.20 PSC72105.1 - 0.012 15.8 0.1 3 8.3 0.0 4.5 4 0 0 4 4 3 0 PPR repeat TPR_6 PF13174.6 PSC72105.1 - 0.022 15.4 10.1 17 6.3 0.1 6.8 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 PSC72105.1 - 0.13 12.4 2.7 2.1 8.6 0.0 4.3 5 0 0 5 5 4 0 Tetratricopeptide repeat DegS PF05384.11 PSC72105.1 - 0.19 11.2 0.7 13 5.3 0.0 2.4 2 0 0 2 2 2 0 Sensor protein DegS XPG_I PF00867.18 PSC72106.1 - 8.4e-25 87.0 0.0 7.6e-24 83.9 0.0 2.6 2 0 0 2 2 2 1 XPG I-region XPG_N PF00752.17 PSC72106.1 - 2.3e-12 47.2 0.0 5.2e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain Histone PF00125.24 PSC72107.1 - 1e-15 58.3 0.0 1.2e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC72107.1 - 0.0077 16.5 0.1 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DnaJ PF00226.31 PSC72107.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain RP-C PF03428.13 PSC72107.1 - 0.06 13.0 0.4 3.4 7.3 0.0 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain TFIID_20kDa PF03847.13 PSC72107.1 - 0.2 12.2 0.0 0.33 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Ubie_methyltran PF01209.18 PSC72109.1 - 8.6e-57 192.1 0.0 1.1e-56 191.8 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 PSC72109.1 - 2.7e-23 82.5 0.0 5.5e-23 81.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC72109.1 - 1.5e-20 73.6 0.0 2.6e-20 72.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC72109.1 - 1.5e-18 67.0 0.0 2.2e-18 66.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC72109.1 - 8.3e-14 52.1 0.0 1.9e-13 51.0 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC72109.1 - 3.3e-10 40.1 0.0 5.5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PSC72109.1 - 7.5e-05 22.6 0.0 0.00011 22.0 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 PSC72109.1 - 0.00097 19.1 0.0 0.0018 18.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PSC72109.1 - 0.014 14.9 0.0 0.022 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.15 PSC72109.1 - 0.064 13.1 0.0 0.2 11.5 0.0 1.7 1 1 1 2 2 2 0 Hypothetical methyltransferase GCD14 PF08704.10 PSC72109.1 - 0.19 11.4 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Methyltransf_4 PF02390.17 PSC72109.1 - 0.21 11.0 0.0 0.43 10.0 0.0 1.5 2 0 0 2 2 2 0 Putative methyltransferase DUF1712 PF08217.11 PSC72110.1 - 4.9e-11 41.8 0.0 4.2e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 Fungal domain of unknown function (DUF1712) PWI PF01480.17 PSC72111.1 - 2.4e-28 98.2 0.1 5.4e-28 97.1 0.1 1.5 1 0 0 1 1 1 1 PWI domain RRF PF01765.19 PSC72111.1 - 6.3 6.7 11.2 19 5.2 11.2 1.8 1 0 0 1 1 1 0 Ribosome recycling factor Pkinase PF00069.25 PSC72112.1 - 3.1e-18 66.1 0.0 1e-17 64.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Polyketide_cyc2 PF10604.9 PSC72112.1 - 6.5e-16 58.9 0.0 4.2e-15 56.3 0.0 2.5 2 0 0 2 2 2 1 Polyketide cyclase / dehydrase and lipid transport WD40 PF00400.32 PSC72112.1 - 7.9e-13 48.7 5.8 0.0012 19.6 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat HEAT PF02985.22 PSC72112.1 - 0.0066 16.6 6.2 0.16 12.3 0.1 4.0 3 0 0 3 3 3 2 HEAT repeat DNA_processg_A PF02481.15 PSC72112.1 - 0.021 14.1 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 DNA recombination-mediator protein A TUG-UBL1 PF11470.8 PSC72114.1 - 1.4e-09 38.0 0.1 3.4e-08 33.6 0.0 2.4 2 1 0 2 2 2 1 TUG ubiquitin-like domain RBD PF02196.15 PSC72114.1 - 0.051 13.6 0.1 8.9 6.5 0.0 2.3 2 0 0 2 2 2 0 Raf-like Ras-binding domain TFIIA PF03153.13 PSC72114.1 - 0.087 12.8 4.7 0.11 12.5 4.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YukD PF08817.10 PSC72114.1 - 0.84 10.4 3.5 7 7.4 0.1 3.1 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD Zip PF02535.22 PSC72115.1 - 1.6e-53 182.0 13.2 1.6e-53 182.0 13.2 2.0 2 0 0 2 2 2 1 ZIP Zinc transporter DUF5504 PF17608.2 PSC72115.1 - 0.056 13.6 0.3 0.15 12.1 0.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5504) Spore_coat_CotO PF14153.6 PSC72115.1 - 8.2 6.3 6.2 14 5.6 6.2 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Cript PF10235.9 PSC72116.1 - 8e-24 84.0 16.6 4.6e-23 81.6 12.1 2.6 2 0 0 2 2 2 2 Microtubule-associated protein CRIPT zinc_ribbon_15 PF17032.5 PSC72116.1 - 0.035 14.9 5.4 0.035 14.9 5.4 3.4 3 1 0 3 3 3 0 zinc-ribbon family LRR_9 PF14580.6 PSC72117.1 - 1.6e-61 206.8 0.3 2.7e-61 206.1 0.3 1.2 1 0 0 1 1 1 1 Leucine-rich repeat AAA PF00004.29 PSC72117.1 - 3.5e-37 127.8 0.0 6.3e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PSC72117.1 - 3.1e-09 36.5 0.1 8.8e-09 35.0 0.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain LRR_4 PF12799.7 PSC72117.1 - 3.4e-09 36.8 6.3 0.00023 21.5 0.5 3.0 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC72117.1 - 7.1e-07 28.9 11.0 3.4e-05 23.5 4.0 2.6 1 1 1 2 2 2 2 Leucine rich repeat AAA_2 PF07724.14 PSC72117.1 - 0.00012 22.2 0.0 0.00026 21.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 PSC72117.1 - 0.00021 21.6 0.1 0.012 15.8 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 PSC72117.1 - 0.002 18.3 0.0 0.0047 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 PSC72117.1 - 0.0022 18.0 0.0 0.0063 16.5 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 PSC72117.1 - 0.0095 16.5 0.0 0.033 14.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 PSC72117.1 - 0.025 14.8 0.0 0.099 12.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 PSC72117.1 - 0.028 13.6 0.0 0.064 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RuvB_N PF05496.12 PSC72117.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PSC72117.1 - 0.16 12.4 0.1 0.16 12.4 0.1 3.3 3 1 1 4 4 4 0 AAA ATPase domain DUF1084 PF06454.11 PSC72118.1 - 2e-117 391.4 0.3 2e-117 391.4 0.3 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1084) FAD_binding_2 PF00890.24 PSC72118.1 - 7.8e-88 295.3 12.2 1.1e-87 294.9 12.2 1.2 1 0 0 1 1 1 1 FAD binding domain Aa_trans PF01490.18 PSC72118.1 - 5.7e-29 101.0 20.2 1e-28 100.2 20.2 1.3 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DAO PF01266.24 PSC72118.1 - 1.1e-12 48.2 2.5 1e-07 31.9 0.8 2.4 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_oxidored PF12831.7 PSC72118.1 - 2.2e-09 37.2 3.0 4.5e-09 36.2 3.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PSC72118.1 - 3.6e-06 26.4 2.7 0.0022 17.3 2.8 2.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PSC72118.1 - 4.7e-06 26.7 0.1 2.6e-05 24.4 0.1 2.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 PSC72118.1 - 0.00059 20.3 0.9 1.7 9.3 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PSC72118.1 - 0.0058 15.8 4.8 0.028 13.5 1.3 2.5 3 0 0 3 3 3 1 Glucose inhibited division protein A Glyoxalase PF00903.25 PSC72118.1 - 0.015 15.5 0.0 0.032 14.4 0.0 1.6 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily GMC_oxred_N PF00732.19 PSC72118.1 - 0.025 14.0 0.4 0.075 12.4 0.0 1.8 2 0 0 2 2 2 0 GMC oxidoreductase HI0933_like PF03486.14 PSC72118.1 - 0.032 13.0 5.6 0.76 8.4 0.9 3.1 3 0 0 3 3 3 0 HI0933-like protein Glyoxalase_6 PF18029.1 PSC72118.1 - 0.063 14.1 1.8 0.15 12.9 0.0 2.6 3 0 0 3 3 2 0 Glyoxalase-like domain Thi4 PF01946.17 PSC72118.1 - 0.96 8.6 4.6 1.7 7.9 0.4 2.7 3 0 0 3 3 3 0 Thi4 family HSP20 PF00011.21 PSC72119.1 - 1.2e-24 86.3 1.2 3.2e-24 85.0 0.6 2.0 2 0 0 2 2 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 PSC72119.1 - 3.1e-07 29.9 1.2 1e-06 28.2 0.5 2.2 1 1 1 2 2 2 1 HSP20-like domain found in ArsA SecD_SecF PF02355.16 PSC72120.1 - 1.9e-25 89.3 25.4 8.9e-15 54.6 2.7 3.2 2 1 1 3 3 3 3 Protein export membrane protein ACR_tran PF00873.19 PSC72120.1 - 6.6e-05 20.8 5.8 0.00012 19.9 5.8 1.4 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family RETICULATA-like PF11891.8 PSC72121.1 - 1.2e-58 197.8 0.0 2.2e-58 197.0 0.0 1.4 1 0 0 1 1 1 1 Protein RETICULATA-related BRO1 PF03097.18 PSC72121.1 - 3.7e-27 95.1 0.0 5.8e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 BRO1-like domain Yae1_N PF09811.9 PSC72121.1 - 3.9e-10 39.3 5.2 8e-10 38.3 5.2 1.6 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Polysacc_synt_C PF14667.6 PSC72121.1 - 3.5 7.7 10.3 0.038 14.1 0.7 2.5 3 0 0 3 3 3 0 Polysaccharide biosynthesis C-terminal domain Histone PF00125.24 PSC72122.1 - 2.9e-54 183.0 1.9 3.2e-54 182.8 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 PSC72122.1 - 0.00013 22.5 1.7 0.00016 22.2 1.7 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 PSC72122.1 - 0.00045 20.5 0.0 0.00069 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 PSC72122.1 - 0.00049 20.2 0.5 0.00074 19.6 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 PSC72122.1 - 0.0052 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PSC72122.1 - 0.016 15.3 0.1 0.031 14.3 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit PRP21_like_P PF12230.8 PSC72123.1 - 3.4e-44 151.3 7.1 1.1e-43 149.6 7.1 1.7 1 1 0 1 1 1 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 PSC72123.1 - 8.9e-39 131.3 2.0 1.8e-19 69.4 0.5 2.4 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 PSC72123.1 - 0.00028 20.6 0.1 0.00059 19.5 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 PSC72123.1 - 0.018 15.5 0.0 0.044 14.2 0.0 1.6 1 0 0 1 1 1 0 Ubiquitin-like domain Whirly PF08536.11 PSC72124.1 - 1e-35 122.5 0.0 1.3e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 Whirly transcription factor U3_assoc_6 PF08640.11 PSC72125.1 - 2.6e-23 81.9 1.0 5.3e-23 80.9 1.0 1.5 1 0 0 1 1 1 1 U3 small nucleolar RNA-associated protein 6 CHCH PF06747.13 PSC72126.1 - 1.1e-07 31.8 13.7 2.9e-07 30.4 6.3 2.4 2 1 0 2 2 2 2 CHCH domain CX9C PF16860.5 PSC72126.1 - 2.5e-06 27.4 11.3 5.5e-05 23.1 4.3 2.2 2 0 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Pet191_N PF10203.9 PSC72126.1 - 0.002 18.4 13.3 0.026 14.8 0.9 3.1 1 1 2 3 3 3 3 Cytochrome c oxidase assembly protein PET191 COX6B PF02297.17 PSC72126.1 - 0.0091 16.2 15.5 0.019 15.2 7.4 2.2 1 1 1 2 2 2 2 Cytochrome oxidase c subunit VIb COX17 PF05051.13 PSC72126.1 - 0.02 15.2 1.0 0.02 15.2 1.0 2.5 2 1 0 2 2 2 0 Cytochrome C oxidase copper chaperone (COX17) Cmc1 PF08583.10 PSC72126.1 - 0.032 14.2 3.8 0.032 14.2 3.8 2.4 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like NDUF_B7 PF05676.13 PSC72126.1 - 1.1 9.0 10.5 4.5 7.1 0.5 2.2 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) zf-RING_2 PF13639.6 PSC72127.1 - 3.2e-12 46.6 7.2 6.1e-12 45.7 7.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PSC72127.1 - 4.2e-08 33.4 5.9 8.3e-08 32.4 5.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 PSC72127.1 - 9.6e-08 31.6 3.3 1.9e-07 30.7 3.3 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PSC72127.1 - 1.4e-07 31.2 7.1 3.9e-07 29.8 7.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC72127.1 - 7.1e-07 29.1 5.9 1.4e-06 28.1 5.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PSC72127.1 - 3.1e-06 27.1 3.1 6.7e-06 26.0 3.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PSC72127.1 - 3.9e-06 26.6 6.5 6.9e-06 25.8 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC72127.1 - 2e-05 24.4 4.6 4e-05 23.4 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PSC72127.1 - 0.00013 21.7 6.5 0.00026 20.8 6.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PSC72127.1 - 0.0019 18.2 2.3 0.0037 17.3 2.3 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 PSC72127.1 - 0.0026 17.9 3.3 0.0053 16.9 3.3 1.5 1 0 0 1 1 1 1 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 PSC72127.1 - 0.0074 15.9 6.6 0.017 14.8 6.6 1.5 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 PSC72127.1 - 0.015 15.1 3.7 0.029 14.1 3.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 PSC72127.1 - 0.36 11.0 7.2 0.75 10.0 7.2 1.5 1 0 0 1 1 1 0 RING-variant domain zf-C3H2C3 PF17122.5 PSC72127.1 - 0.82 9.8 6.4 44 4.2 6.1 2.8 2 0 0 2 2 2 0 Zinc-finger NAD_binding_10 PF13460.6 PSC72129.1 - 1.2e-08 35.1 4.5 1.2e-08 35.1 4.5 2.6 2 1 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 PSC72129.1 - 0.019 14.5 0.5 0.033 13.7 0.5 1.4 1 0 0 1 1 1 0 NmrA-like family Lipase_3 PF01764.25 PSC72130.1 - 5.1e-08 32.9 0.0 1.1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Ribonuc_2-5A PF06479.12 PSC72130.1 - 0.13 12.5 0.1 0.42 10.8 0.2 1.8 2 0 0 2 2 2 0 Ribonuclease 2-5A Tropomyosin_1 PF12718.7 PSC72130.1 - 3 8.0 22.5 3.2 7.9 13.3 3.0 1 1 1 2 2 2 0 Tropomyosin like HSP70 PF00012.20 PSC72131.1 - 3e-153 511.2 0.7 1e-152 509.4 0.0 2.1 2 1 0 2 2 2 1 Hsp70 protein TPR_2 PF07719.17 PSC72131.1 - 1.1e-11 44.0 20.1 1.4e-08 34.2 1.0 4.9 5 0 0 5 5 5 3 Tetratricopeptide repeat Glycos_transf_1 PF00534.20 PSC72131.1 - 1.8e-11 43.9 0.0 3.9e-11 42.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PSC72131.1 - 1.7e-10 41.4 0.0 3.8e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 TPR_1 PF00515.28 PSC72131.1 - 1.9e-10 40.1 15.5 6.1e-09 35.3 0.4 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat MreB_Mbl PF06723.13 PSC72131.1 - 8.7e-07 28.1 0.0 2.1e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 MreB/Mbl protein TPR_8 PF13181.6 PSC72131.1 - 2.4e-06 27.3 9.2 3.4e-05 23.7 0.2 4.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.6 PSC72131.1 - 7.4e-05 22.8 1.6 0.0004 20.5 1.2 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 PSC72131.1 - 0.00052 19.6 5.8 0.00064 19.4 0.5 3.3 3 0 0 3 3 3 1 TPR repeat Glyco_trans_1_2 PF13524.6 PSC72131.1 - 0.00056 20.3 2.7 0.0011 19.3 0.0 3.0 3 0 0 3 3 2 1 Glycosyl transferases group 1 TPR_17 PF13431.6 PSC72131.1 - 0.0015 18.7 0.5 16 6.2 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 PSC72131.1 - 0.0017 19.0 0.4 0.0017 19.0 0.4 5.2 5 0 0 5 5 3 1 Tetratricopeptide repeat TPR_3 PF07720.12 PSC72131.1 - 0.0018 18.2 1.7 0.016 15.2 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 PSC72131.1 - 0.0032 17.7 10.0 0.044 14.1 0.2 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PSC72131.1 - 0.018 15.1 1.3 0.061 13.4 0.3 2.4 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 PSC72131.1 - 0.052 14.2 17.0 0.057 14.1 0.5 4.4 4 0 0 4 4 2 0 Tetratricopeptide repeat Apolipoprotein PF01442.18 PSC72131.1 - 0.84 9.5 22.4 0.8 9.6 2.4 3.6 3 0 0 3 3 3 0 Apolipoprotein A1/A4/E domain TPR_6 PF13174.6 PSC72131.1 - 0.84 10.4 10.8 0.087 13.5 0.4 4.1 4 0 0 4 4 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 PSC72131.1 - 2.9 7.9 13.5 0.27 11.2 1.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Fea1 PF07692.11 PSC72132.1 - 4e-08 32.7 0.5 1e-07 31.3 0.5 1.7 1 1 0 1 1 1 1 Low iron-inducible periplasmic protein Kazal_2 PF07648.15 PSC72132.1 - 0.00029 20.9 4.7 0.00054 20.0 4.7 1.4 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Kazal_1 PF00050.21 PSC72132.1 - 0.0071 16.3 6.9 0.014 15.4 6.9 1.6 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Rft-1 PF04506.13 PSC72133.1 - 6e-98 328.8 0.0 8.7e-98 328.3 0.0 1.2 1 0 0 1 1 1 1 Rft protein Polysacc_synt_3 PF13440.6 PSC72133.1 - 0.00027 20.2 0.2 0.085 12.1 0.0 2.4 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Polysacc_synt PF01943.17 PSC72133.1 - 1.8 7.8 8.7 0.96 8.8 0.4 3.6 4 0 0 4 4 4 0 Polysaccharide biosynthesis protein Histone PF00125.24 PSC72134.1 - 9.9e-16 58.3 0.1 1.3e-15 57.9 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC72134.1 - 0.0077 16.5 0.1 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DnaJ PF00226.31 PSC72134.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain RP-C PF03428.13 PSC72134.1 - 0.06 13.0 0.4 3.4 7.3 0.0 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain TFIID_20kDa PF03847.13 PSC72134.1 - 0.2 12.2 0.0 0.33 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Prefoldin_2 PF01920.20 PSC72135.1 - 7.5e-21 74.1 3.3 8.4e-21 73.9 3.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit OmpH PF03938.14 PSC72135.1 - 0.024 15.0 2.8 0.05 13.9 0.0 2.0 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Q_salvage PF10343.9 PSC72135.1 - 0.12 11.9 0.2 0.15 11.6 0.2 1.1 1 0 0 1 1 1 0 Potential Queuosine, Q, salvage protein family FTHFS PF01268.19 PSC72136.1 - 8.5e-252 836.3 0.3 1.1e-251 835.9 0.3 1.1 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase Histone PF00125.24 PSC72136.1 - 1e-50 171.5 1.0 1.9e-50 170.6 1.0 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Gpr1_Fun34_YaaH PF01184.19 PSC72136.1 - 3.8e-30 105.0 14.9 7.4e-30 104.1 14.9 1.4 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family CENP-S PF15630.6 PSC72136.1 - 0.0084 16.5 0.0 0.018 15.4 0.0 1.5 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 PSC72136.1 - 0.011 15.9 0.0 0.024 14.8 0.0 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold CbiA PF01656.23 PSC72136.1 - 0.057 13.5 0.3 0.17 12.0 0.3 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain CBFD_NFYB_HMF PF00808.23 PSC72136.1 - 0.11 12.8 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ion_trans_N PF08412.10 PSC72136.1 - 0.16 11.6 0.0 0.44 10.2 0.0 1.7 1 0 0 1 1 1 0 Ion transport protein N-terminal PAF PF15715.5 PSC72136.1 - 0.18 12.4 0.9 0.36 11.4 0.9 1.4 1 0 0 1 1 1 0 PCNA-associated factor histone like domain Keratin_assoc PF09775.9 PSC72136.1 - 0.84 9.3 7.7 2.5 7.7 7.7 1.7 1 0 0 1 1 1 0 Keratinocyte-associated protein 2 DUF572 PF04502.13 PSC72137.1 - 5.3e-56 190.6 0.0 5.3e-56 190.6 0.0 3.5 1 1 0 3 3 3 1 Family of unknown function (DUF572) Vps5 PF09325.10 PSC72138.1 - 6.6e-25 88.0 0.4 9.8e-25 87.5 0.4 1.3 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 PSC72138.1 - 1.1e-24 86.5 0.0 2.7e-24 85.3 0.0 1.6 1 0 0 1 1 1 1 PX domain BAR PF03114.18 PSC72138.1 - 1.3e-05 24.9 0.8 0.00024 20.8 0.5 2.4 1 1 0 1 1 1 1 BAR domain TerB_N PF13208.6 PSC72138.1 - 0.057 13.1 0.2 0.15 11.7 0.1 1.8 2 0 0 2 2 2 0 TerB N-terminal domain Filament PF00038.21 PSC72138.1 - 1.3 8.5 6.0 0.32 10.5 1.6 1.8 2 0 0 2 2 2 0 Intermediate filament protein Bclt PF15318.6 PSC72138.1 - 2.5 7.9 6.8 1.1 9.1 4.0 1.7 2 0 0 2 2 2 0 Putative Bcl-2 like protein of testis WD40 PF00400.32 PSC72139.1 - 3.8e-24 84.5 8.2 6.7e-07 29.9 0.0 6.0 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC72139.1 - 0.00016 21.9 0.0 1.5 9.1 0.0 4.4 3 1 2 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PSC72139.1 - 0.00027 20.0 1.0 2.8 6.8 0.1 3.6 2 1 2 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 PSC72139.1 - 0.03 14.3 0.0 15 5.7 0.0 3.4 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat Lactonase PF10282.9 PSC72139.1 - 0.22 10.8 0.0 1.7 7.8 0.0 2.0 1 1 1 2 2 2 0 Lactonase, 7-bladed beta-propeller PQQ_3 PF13570.6 PSC72139.1 - 0.46 11.0 11.4 20 5.9 0.6 4.8 4 1 1 5 5 5 0 PQQ-like domain PGM_PMM_I PF02878.16 PSC72140.1 - 1.7e-18 66.7 1.0 2.6e-08 33.7 0.0 3.2 3 1 1 4 4 4 2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_IV PF00408.20 PSC72140.1 - 2.4e-11 43.6 0.2 6.7e-11 42.2 0.2 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain PGM_PMM_III PF02880.16 PSC72140.1 - 0.00038 20.6 0.0 0.0011 19.1 0.0 1.9 1 1 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 PSC72140.1 - 0.0096 16.5 0.0 0.045 14.4 0.0 2.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II DUF3197 PF11432.8 PSC72140.1 - 0.12 12.3 0.1 0.39 10.6 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3197) Lipase_3 PF01764.25 PSC72141.1 - 1.4e-27 96.3 0.0 2.8e-27 95.3 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.7 PSC72141.1 - 0.0074 16.9 2.1 0.0074 16.9 2.1 3.2 2 1 1 3 3 3 1 Alpha/beta hydrolase family DUF2974 PF11187.8 PSC72141.1 - 0.031 13.8 0.0 0.049 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 PSC72141.1 - 0.063 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_8 PF06259.12 PSC72141.1 - 0.086 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase L6_membrane PF05805.12 PSC72141.1 - 7.4 6.1 8.6 0.26 10.8 1.3 2.4 3 1 1 4 4 4 0 L6 membrane protein ABC2_membrane PF01061.24 PSC72142.1 - 2.2e-29 102.4 25.6 3e-29 101.9 25.6 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PSC72142.1 - 3.6e-23 82.6 0.0 5.9e-23 81.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 PSC72142.1 - 0.0001 22.3 0.1 0.00017 21.6 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 PSC72142.1 - 0.00036 20.4 0.0 0.17 11.6 0.0 2.3 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PSC72142.1 - 0.00038 20.9 0.0 0.00074 19.9 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 PSC72142.1 - 0.00064 19.7 0.0 0.0016 18.4 0.0 1.6 2 0 0 2 2 2 1 Rad17 P-loop domain NTPase_1 PF03266.15 PSC72142.1 - 0.00075 19.5 0.0 0.18 11.7 0.0 2.2 2 0 0 2 2 2 1 NTPase AAA_22 PF13401.6 PSC72142.1 - 0.00077 19.8 0.0 0.0014 18.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 PSC72142.1 - 0.0012 18.4 0.2 0.0032 17.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.6 PSC72142.1 - 0.0014 18.3 0.1 0.0028 17.4 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain NACHT PF05729.12 PSC72142.1 - 0.0035 17.3 0.0 0.0069 16.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain AAA_18 PF13238.6 PSC72142.1 - 0.005 17.4 0.0 0.12 12.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 PSC72142.1 - 0.013 15.8 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 PSC72142.1 - 0.02 15.3 0.0 0.15 12.5 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 PSC72142.1 - 0.027 15.0 0.1 0.042 14.4 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PSC72142.1 - 0.035 14.4 0.0 0.072 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PSC72142.1 - 0.037 14.0 0.0 0.09 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 PSC72142.1 - 0.045 13.7 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_14 PF13173.6 PSC72142.1 - 0.051 13.6 0.0 0.11 12.5 0.0 1.6 2 0 0 2 2 1 0 AAA domain MobB PF03205.14 PSC72142.1 - 0.078 12.9 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_24 PF13479.6 PSC72142.1 - 0.086 12.6 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 PSC72142.1 - 0.088 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PSC72142.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 PSC72142.1 - 0.14 12.5 0.0 0.28 11.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 PSC72142.1 - 0.21 11.7 0.0 0.43 10.7 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.7 PSC72142.1 - 1 8.4 21.4 0.43 9.6 15.7 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein PhoLip_ATPase_C PF16212.5 PSC72142.1 - 1.9 8.2 19.7 0.23 11.2 4.9 2.1 1 1 1 2 2 2 0 Phospholipid-translocating P-type ATPase C-terminal UPF0182 PF03699.13 PSC72142.1 - 2.1 6.4 10.1 3.1 5.8 10.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) CENP-T_C PF15511.6 PSC72143.1 - 2e-08 34.3 0.1 2.5e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PSC72143.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 PSC72143.1 - 0.00022 21.3 0.1 0.00031 20.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 PSC72143.1 - 0.0011 18.9 0.1 0.0017 18.4 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 PSC72143.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PSC72143.1 - 0.0015 18.9 0.1 0.0017 18.8 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 PSC72143.1 - 0.033 14.3 0.0 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Pkinase_Tyr PF07714.17 PSC72144.1 - 8.2e-56 189.2 0.0 7.9e-55 185.9 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC72144.1 - 1.2e-42 146.1 0.0 1.9e-42 145.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PSC72144.1 - 4.5e-08 32.7 3.2 8e-08 31.9 3.2 1.4 1 0 0 1 1 1 1 Leucine rich repeat LRRNT_2 PF08263.12 PSC72144.1 - 1.7e-07 31.4 0.4 4e-07 30.2 0.4 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 PSC72144.1 - 9.1e-05 22.8 13.7 0.00035 20.9 1.8 2.4 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) F5_F8_type_C PF00754.25 PSC72144.1 - 9.9e-05 22.5 0.0 0.47 10.6 0.0 2.5 2 0 0 2 2 2 2 F5/8 type C domain LRR_1 PF00560.33 PSC72144.1 - 0.00021 21.4 1.4 0.33 11.6 0.1 3.7 3 0 0 3 3 3 1 Leucine Rich Repeat Haspin_kinase PF12330.8 PSC72144.1 - 0.00078 18.5 0.0 0.0028 16.7 0.0 1.7 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 PSC72144.1 - 0.002 18.1 0.0 0.0059 16.6 0.0 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PSC72144.1 - 0.15 11.3 0.0 0.26 10.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like SHMT PF00464.19 PSC72145.1 - 9.5e-191 633.6 0.0 1.3e-190 633.2 0.0 1.2 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Helicase_C PF00271.31 PSC72145.1 - 2e-16 60.3 0.0 7.9e-16 58.4 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 PSC72145.1 - 2.1e-15 56.9 0.3 1.8e-14 53.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase RNase_T PF00929.24 PSC72145.1 - 5.7e-11 43.2 0.0 1.6e-10 41.8 0.0 1.8 2 0 0 2 2 2 1 Exonuclease ResIII PF04851.15 PSC72145.1 - 1.9e-09 37.8 0.0 4.2e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Rogdi_lz PF10259.9 PSC72145.1 - 0.038 13.4 0.1 3.1 7.2 0.0 2.2 2 0 0 2 2 2 0 Rogdi leucine zipper containing protein MAGI_u5 PF16666.5 PSC72145.1 - 0.097 12.8 7.1 0.24 11.6 7.1 1.6 1 0 0 1 1 1 0 Unstructured region on MAGI ERCC3_RAD25_C PF16203.5 PSC72145.1 - 0.15 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase TsaE PF02367.17 PSC72145.1 - 0.17 11.9 0.0 0.48 10.4 0.0 1.7 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE mRNA_cap_enzyme PF01331.19 PSC72146.1 - 2.5e-54 184.1 0.0 3.5e-54 183.6 0.0 1.2 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 PSC72146.1 - 3.4e-18 66.3 0.0 7.8e-18 65.1 0.0 1.6 1 1 0 1 1 1 1 mRNA capping enzyme, C-terminal domain DSPc PF00782.20 PSC72146.1 - 1e-07 31.8 0.0 2.5e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain DNA_ligase_A_M PF01068.21 PSC72146.1 - 0.00027 20.6 0.0 0.027 14.1 0.0 2.7 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Y_phosphatase3 PF13350.6 PSC72146.1 - 0.04 13.9 0.0 0.084 12.8 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family CtsR_C PF17727.1 PSC72146.1 - 0.19 11.9 0.4 7.9 6.7 0.0 2.5 2 1 1 3 3 3 0 CtsR C-terminal dimerization domain Lipase_3 PF01764.25 PSC72147.1 - 1.1e-25 90.1 0.0 2.2e-24 85.9 0.0 2.3 2 0 0 2 2 2 1 Lipase (class 3) C2 PF00168.30 PSC72147.1 - 1.5e-17 63.8 0.0 2.5e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 C2 domain DUF4315 PF14193.6 PSC72147.1 - 0.011 15.7 1.7 0.023 14.7 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) Hydrolase_4 PF12146.8 PSC72147.1 - 0.062 12.5 0.1 0.2 10.9 0.1 1.9 1 1 0 1 1 1 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 PSC72147.1 - 0.094 12.3 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) KDZ PF18758.1 PSC72148.1 - 1.4e-11 44.5 0.1 2e-11 43.9 0.1 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF2269 PF10027.9 PSC72148.1 - 0.002 18.2 2.2 0.0036 17.4 0.7 2.0 2 0 0 2 2 2 1 Predicted integral membrane protein (DUF2269) WD40 PF00400.32 PSC72149.1 - 2.4e-43 145.2 7.0 3e-07 31.0 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC72149.1 - 2.3e-13 50.2 0.1 2e-07 31.2 0.0 4.1 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PSC72149.1 - 6.2e-07 29.5 0.0 0.00084 19.3 0.0 3.1 2 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 PSC72149.1 - 5.7e-05 22.2 0.0 0.042 12.8 0.0 3.3 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nbas_N PF15492.6 PSC72149.1 - 0.048 13.0 0.0 0.66 9.3 0.0 2.5 2 1 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.8 PSC72149.1 - 0.059 12.0 0.4 1.6 7.3 0.1 2.7 2 1 1 3 3 3 0 Nucleoporin Nup120/160 PD40 PF07676.12 PSC72149.1 - 0.26 11.3 2.0 63 3.7 0.3 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat ABC2_membrane PF01061.24 PSC72150.1 - 1.8e-30 105.9 30.2 2.8e-30 105.3 30.2 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PSC72150.1 - 2.2e-23 83.3 0.0 3.5e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 PSC72150.1 - 3.6e-05 23.7 0.1 6.6e-05 22.9 0.1 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 PSC72150.1 - 0.00035 20.9 0.0 0.00087 19.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_21 PF13304.6 PSC72150.1 - 0.00043 20.2 0.0 0.11 12.3 0.0 2.2 1 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PSC72150.1 - 0.00047 20.6 0.0 0.001 19.4 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 PSC72150.1 - 0.00086 18.9 0.0 0.0064 16.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.6 PSC72150.1 - 0.0011 18.7 0.1 0.0021 17.7 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain Rad17 PF03215.15 PSC72150.1 - 0.0018 18.2 0.0 0.0032 17.4 0.0 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain NACHT PF05729.12 PSC72150.1 - 0.0025 17.7 0.0 0.0055 16.6 0.0 1.6 1 0 0 1 1 1 1 NACHT domain RNA_helicase PF00910.22 PSC72150.1 - 0.0086 16.4 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase ATPase_2 PF01637.18 PSC72150.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_23 PF13476.6 PSC72150.1 - 0.022 15.3 0.0 0.034 14.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 PSC72150.1 - 0.023 14.1 0.1 0.58 9.6 0.0 2.4 3 0 0 3 3 2 0 RecF/RecN/SMC N terminal domain NTPase_1 PF03266.15 PSC72150.1 - 0.023 14.6 0.0 0.47 10.4 0.0 2.3 2 0 0 2 2 2 0 NTPase MobB PF03205.14 PSC72150.1 - 0.024 14.5 0.0 0.04 13.8 0.0 1.3 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.6 PSC72150.1 - 0.038 14.2 0.1 0.077 13.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 PSC72150.1 - 0.053 13.2 0.0 0.099 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 PSC72150.1 - 0.059 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 PSC72150.1 - 0.06 13.8 0.0 0.15 12.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) T2SSE PF00437.20 PSC72150.1 - 0.067 12.2 0.0 0.11 11.5 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein MMR_HSR1 PF01926.23 PSC72150.1 - 0.083 13.0 0.1 0.34 11.0 0.0 2.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase AAA_18 PF13238.6 PSC72150.1 - 0.11 13.1 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 PSC72150.1 - 0.12 12.5 0.0 0.23 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 PSC72150.1 - 0.15 11.8 0.1 0.27 10.9 0.1 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family NB-ARC PF00931.22 PSC72150.1 - 0.15 11.2 0.1 0.25 10.5 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain C1ORF64 PF15547.6 PSC72150.1 - 0.16 12.4 0.1 0.29 11.6 0.1 1.4 1 0 0 1 1 1 0 Steroid receptor-associated and regulated protein Mg_chelatase PF01078.21 PSC72150.1 - 0.18 11.2 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PSC72150.1 - 0.18 11.8 0.0 0.47 10.5 0.0 1.7 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) SbcCD_C PF13558.6 PSC72150.1 - 0.2 11.9 0.6 0.96 9.7 0.0 2.6 4 0 0 4 4 1 0 Putative exonuclease SbcCD, C subunit ABC2_membrane_3 PF12698.7 PSC72150.1 - 2.9 6.9 27.8 11 5.0 27.8 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein tRNA-synt_2b PF00587.25 PSC72151.1 - 4.1e-18 66.0 0.0 6.6e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 PSC72151.1 - 6.9e-14 51.8 0.1 1.9e-13 50.4 0.0 1.8 2 0 0 2 2 2 1 Anticodon binding domain ProRS-C_1 PF09180.11 PSC72151.1 - 1.6e-12 47.4 0.1 3.7e-12 46.3 0.1 1.6 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal CbiA PF01656.23 PSC72152.1 - 0.039 14.0 0.2 0.076 13.1 0.2 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain LRV PF01816.17 PSC72152.1 - 0.12 12.8 5.2 4.2 8.0 0.0 3.7 3 0 0 3 3 3 0 Leucine rich repeat variant Glyoxalase PF00903.25 PSC72153.1 - 5.4e-08 33.1 0.0 1.3e-07 31.9 0.0 1.7 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 PSC72153.1 - 0.00011 22.1 0.0 0.00021 21.2 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_6 PF18029.1 PSC72153.1 - 0.00084 20.1 0.0 0.0015 19.3 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.6 PSC72153.1 - 0.0057 16.9 0.0 0.011 16.0 0.0 1.4 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 PSC72153.1 - 0.085 13.0 0.0 5.6 7.0 0.0 2.2 2 0 0 2 2 2 0 Glyoxalase-like domain Histone PF00125.24 PSC72154.1 - 1e-15 58.3 0.0 1.2e-15 58.0 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC72154.1 - 0.0077 16.5 0.1 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DnaJ PF00226.31 PSC72154.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain RP-C PF03428.13 PSC72154.1 - 0.06 13.0 0.4 3.4 7.3 0.0 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain TFIID_20kDa PF03847.13 PSC72154.1 - 0.2 12.2 0.0 0.33 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A NAD_binding_1 PF00175.21 PSC72155.1 - 4.7e-25 88.3 0.0 6.8e-25 87.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 PSC72155.1 - 1.1e-18 67.4 0.0 2e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 PSC72155.1 - 0.012 15.7 0.0 0.14 12.3 0.0 2.1 1 1 1 2 2 2 0 Ferric reductase NAD binding domain LRR_4 PF12799.7 PSC72156.1 - 5.2e-06 26.7 8.6 0.53 10.8 0.3 6.3 4 2 3 7 7 7 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PSC72156.1 - 0.00031 20.9 9.7 2.3 9.1 0.1 6.2 7 0 0 7 7 7 2 Leucine Rich Repeat LRR_8 PF13855.6 PSC72156.1 - 0.023 14.5 19.7 7.3 6.4 0.1 7.4 7 2 1 8 8 8 0 Leucine rich repeat SMC_N PF02463.19 PSC72157.1 - 8e-78 260.8 0.0 1.1e-77 260.3 0.0 1.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 PSC72157.1 - 2.8e-25 88.9 0.1 6.9e-25 87.6 0.1 1.7 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 PSC72157.1 - 3.8e-11 43.4 0.1 6.6e-05 22.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 PSC72157.1 - 6.6e-09 36.0 3.6 6.6e-09 36.0 3.6 3.0 2 1 0 2 2 2 1 AAA ATPase domain Spc7 PF08317.11 PSC72157.1 - 2.6e-06 26.6 8.8 2.6e-06 26.6 8.8 7.2 3 2 4 7 7 7 4 Spc7 kinetochore protein AAA_29 PF13555.6 PSC72157.1 - 3.8e-06 26.5 0.0 8.7e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Filament PF00038.21 PSC72157.1 - 0.0003 20.5 16.9 0.0003 20.5 16.9 5.9 2 2 2 4 4 4 1 Intermediate filament protein ABC_tran PF00005.27 PSC72157.1 - 0.23 12.0 0.0 0.23 12.0 0.0 5.5 4 2 0 4 4 4 0 ABC transporter FlaC_arch PF05377.11 PSC72157.1 - 0.56 10.6 25.5 18 5.8 0.0 8.6 8 2 3 11 11 11 0 Flagella accessory protein C (FlaC) Fez1 PF06818.15 PSC72157.1 - 2 8.8 87.1 0.19 12.2 19.0 6.1 2 2 3 5 5 5 0 Fez1 Kelch_6 PF13964.6 PSC72160.1 - 8.1e-15 54.5 11.3 8.1e-06 25.9 0.0 6.0 4 2 3 7 7 7 4 Kelch motif Glyco_trans_4_5 PF16994.5 PSC72160.1 - 1.6e-09 37.6 0.2 2.6e-09 36.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl-transferase family 4 Glycos_transf_1 PF00534.20 PSC72160.1 - 6.2e-09 35.6 0.0 5.9e-08 32.4 0.0 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PSC72160.1 - 2.3e-08 34.6 0.1 5.8e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Kelch_1 PF01344.25 PSC72160.1 - 1.6e-07 30.8 0.7 0.031 13.8 0.0 4.5 4 0 0 4 4 4 2 Kelch motif Kelch_4 PF13418.6 PSC72160.1 - 5.6e-07 29.5 1.9 0.53 10.3 0.1 4.9 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_2 PF07646.15 PSC72160.1 - 0.034 14.1 9.4 2 8.5 0.1 4.8 5 0 0 5 5 5 0 Kelch motif Kelch_5 PF13854.6 PSC72160.1 - 0.081 12.9 0.8 30 4.7 0.0 4.0 5 0 0 5 5 5 0 Kelch motif Kelch_3 PF13415.6 PSC72160.1 - 3.2 8.2 21.2 2.5 8.5 0.2 6.0 7 0 0 7 7 7 0 Galactose oxidase, central domain Ribul_P_3_epim PF00834.19 PSC72161.1 - 1.2e-54 184.7 0.0 1.9e-54 184.1 0.0 1.3 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family FGGY_N PF00370.21 PSC72161.1 - 7.8e-40 137.0 0.0 1.1e-39 136.5 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 PSC72161.1 - 3.5e-39 134.6 0.4 7.7e-39 133.5 0.4 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain TMP-TENI PF02581.17 PSC72161.1 - 0.11 11.9 0.1 0.33 10.2 0.1 1.9 1 0 0 1 1 1 0 Thiamine monophosphate synthase XPG_I PF00867.18 PSC72162.1 - 2.2e-22 79.2 0.0 5.6e-22 77.9 0.0 1.8 1 0 0 1 1 1 1 XPG I-region XPG_I_2 PF12813.7 PSC72162.1 - 2.3e-08 33.8 0.0 5.4e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 XPG domain containing XPG_N PF00752.17 PSC72162.1 - 9.5e-05 22.8 0.0 0.00024 21.5 0.0 1.7 1 0 0 1 1 1 1 XPG N-terminal domain TPR_2 PF07719.17 PSC72162.1 - 0.014 15.4 0.1 0.042 14.0 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 PSC72162.1 - 0.081 13.8 0.4 0.081 13.8 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 PSC72162.1 - 0.15 12.3 0.0 0.41 11.0 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_S10 PF00338.22 PSC72163.1 - 7e-35 119.2 0.1 9.7e-35 118.7 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e zf_CCCH_4 PF18345.1 PSC72164.1 - 2.8e-12 46.3 10.7 5.1e-06 26.4 1.1 2.2 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_3 PF15663.5 PSC72164.1 - 9.9e-12 45.1 1.1 1.9e-05 24.8 0.0 2.3 2 0 0 2 2 2 2 Zinc-finger containing family zf-CCCH PF00642.24 PSC72164.1 - 1.4e-07 31.3 8.8 8.5e-06 25.5 1.5 2.2 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 PSC72164.1 - 5.5e-05 23.5 9.4 0.029 14.9 1.2 2.3 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH_4 PF18044.1 PSC72164.1 - 9.6e-05 22.1 11.1 0.0072 16.1 2.5 2.2 2 0 0 2 2 2 2 CCCH-type zinc finger Torus PF16131.5 PSC72164.1 - 0.00015 22.4 12.4 0.022 15.4 0.9 3.0 2 1 1 3 3 3 2 Torus domain Lipase_GDSL_2 PF13472.6 PSC72165.1 - 7.4e-09 36.2 1.7 1.4e-08 35.3 0.5 2.1 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_3 PF14606.6 PSC72165.1 - 0.15 12.1 0.0 0.38 10.9 0.0 1.6 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family RRM_1 PF00076.22 PSC72166.1 - 7.8e-58 192.2 0.2 1.2e-17 63.4 0.1 6.3 5 1 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PSC72166.1 - 0.00024 21.1 0.1 0.12 12.5 0.0 3.5 3 0 0 3 3 3 1 RNA recognition motif RRM_occluded PF16842.5 PSC72166.1 - 0.011 15.6 0.0 0.037 13.9 0.0 2.0 1 0 0 1 1 1 0 Occluded RNA-recognition motif DNA_pol_phi PF04931.13 PSC72166.1 - 0.82 7.7 16.8 1.6 6.8 16.8 1.4 1 0 0 1 1 1 0 DNA polymerase phi C2 PF00168.30 PSC72167.1 - 6.1e-14 52.2 0.0 7.5e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 C2 domain Histone_H2A_C PF16211.5 PSC72168.1 - 1.6e-20 72.5 2.1 3.3e-20 71.5 2.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 PSC72168.1 - 1.8e-15 57.4 0.0 2.3e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC72168.1 - 1.5e-05 25.1 0.0 2.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone YidD PF01809.18 PSC72169.1 - 1.9e-24 85.3 0.3 2.5e-24 84.9 0.3 1.2 1 0 0 1 1 1 1 Putative membrane protein insertion efficiency factor Cytochrom_B561 PF03188.16 PSC72170.1 - 5.1e-36 123.8 2.6 5.1e-36 123.8 2.6 1.4 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 Ni_hydr_CYTB PF01292.20 PSC72170.1 - 1.1 8.8 14.2 1.7 8.2 9.8 3.1 1 1 1 2 2 2 0 Prokaryotic cytochrome b561 DUF5323 PF17257.2 PSC72171.1 - 9e-08 31.9 6.2 9.9e-08 31.7 6.2 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5323) NmrA PF05368.13 PSC72172.1 - 2.6e-27 95.9 0.0 3.5e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 PSC72172.1 - 9.3e-25 87.6 0.0 1.5e-24 86.9 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 PSC72172.1 - 5.2e-13 49.0 0.0 8e-09 35.3 0.0 3.0 2 1 1 3 3 3 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PSC72172.1 - 1.1e-05 24.7 0.0 1.9e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 PSC72172.1 - 0.0015 17.7 0.0 0.0095 15.1 0.0 2.0 2 0 0 2 2 2 1 RmlD substrate binding domain adh_short PF00106.25 PSC72172.1 - 0.0018 17.8 0.0 0.0029 17.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 PSC72172.1 - 0.025 14.0 0.0 0.34 10.2 0.0 2.5 2 1 1 3 3 3 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 PSC72172.1 - 0.028 14.7 0.0 0.092 13.0 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain DapB_N PF01113.20 PSC72172.1 - 0.13 12.4 0.0 0.31 11.2 0.0 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 PSC72172.1 - 0.16 11.1 0.0 0.7 9.0 0.0 2.0 2 0 0 2 2 2 0 Male sterility protein Seipin PF06775.14 PSC72173.1 - 4.5e-14 53.0 0.0 6.2e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DUF1778 PF08681.11 PSC72174.1 - 0.04 13.8 4.9 0.043 13.7 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1778) DUF3918 PF13056.6 PSC72174.1 - 7.1 6.3 5.5 19 5.0 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3918) adh_short PF00106.25 PSC72175.1 - 9.1e-27 93.8 0.0 3.1e-19 69.2 0.1 2.4 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PSC72175.1 - 1.4e-20 73.8 0.1 4.3e-12 46.1 0.1 2.5 2 1 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC72175.1 - 9.6e-07 28.9 0.1 1.7e-06 28.1 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PSC72175.1 - 0.0026 17.3 0.1 0.0054 16.2 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PSC72175.1 - 0.0046 16.0 0.0 0.006 15.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 PSC72175.1 - 0.0054 17.0 0.1 0.024 14.9 0.0 1.9 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 PSC72175.1 - 0.0085 16.0 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 PSC72175.1 - 0.01 15.2 0.0 0.058 12.8 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Rbsn PF11464.8 PSC72175.1 - 0.21 11.3 0.3 0.37 10.6 0.3 1.3 1 0 0 1 1 1 0 Rabenosyn Rab binding domain Histone PF00125.24 PSC72176.1 - 2.9e-54 183.0 1.9 3.2e-54 182.8 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 PSC72176.1 - 0.00013 22.5 1.7 0.00016 22.2 1.7 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 PSC72176.1 - 0.00045 20.5 0.0 0.00069 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 PSC72176.1 - 0.00049 20.2 0.5 0.00074 19.6 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 PSC72176.1 - 0.0052 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PSC72176.1 - 0.016 15.3 0.1 0.031 14.3 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit SWIRM-assoc_2 PF16496.5 PSC72177.1 - 4.6e-47 160.8 0.0 7.3e-47 160.2 0.0 1.2 1 0 0 1 1 1 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 PSC72177.1 - 2.9e-21 75.6 0.2 6.5e-21 74.5 0.2 1.6 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 PSC72177.1 - 2.5e-16 59.4 6.2 7.2e-16 57.9 6.2 1.8 1 0 0 1 1 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 PSC72177.1 - 4.4e-13 49.2 3.7 1.5e-12 47.5 0.0 2.8 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC72177.1 - 2.3e-08 34.1 0.4 1.6e-07 31.5 0.0 2.4 3 0 0 3 3 3 1 Myb-like DNA-binding domain ZZ PF00569.17 PSC72177.1 - 0.00082 19.1 2.5 0.0016 18.2 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type GrpB PF04229.14 PSC72177.1 - 0.047 13.9 0.2 0.12 12.6 0.2 1.6 1 0 0 1 1 1 0 GrpB protein BRCT PF00533.26 PSC72177.1 - 0.052 13.9 0.0 0.15 12.4 0.0 1.7 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain Cu_amine_oxid PF01179.20 PSC72178.1 - 6e-149 496.4 0.0 7.5e-149 496.1 0.0 1.1 1 0 0 1 1 1 1 Copper amine oxidase, enzyme domain rve PF00665.26 PSC72178.1 - 1.6e-18 67.0 0.0 3.1e-18 66.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain Cu_amine_oxidN3 PF02728.16 PSC72178.1 - 4.9e-08 33.3 0.0 9.6e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Copper amine oxidase, N3 domain rve_3 PF13683.6 PSC72178.1 - 0.01 15.6 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Adenylsucc_synt PF00709.21 PSC72179.1 - 0.0026 16.8 0.0 0.084 11.8 0.0 2.0 1 1 1 2 2 2 2 Adenylosuccinate synthetase Adaptin_N PF01602.20 PSC72180.1 - 9.3e-81 272.0 0.0 1.2e-80 271.6 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_EZ PF13513.6 PSC72180.1 - 5e-09 36.5 1.1 0.047 14.2 0.0 6.1 4 0 0 4 4 4 3 HEAT-like repeat HEAT_2 PF13646.6 PSC72180.1 - 0.0018 18.6 20.0 0.59 10.6 0.1 5.5 3 2 1 4 4 4 3 HEAT repeats Cnd1 PF12717.7 PSC72180.1 - 0.01 15.9 0.2 0.71 9.9 0.0 3.3 4 0 0 4 4 4 0 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PSC72180.1 - 0.019 15.2 11.2 14 6.3 0.0 6.8 6 1 1 7 7 7 0 HEAT repeat PDZ_3 PF17815.1 PSC72182.1 - 6.7e-33 113.6 0.0 1e-32 113.0 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Evr1_Alr PF04777.13 PSC72182.1 - 4.8e-21 75.1 0.1 9.7e-20 70.9 0.3 2.4 2 0 0 2 2 2 1 Erv1 / Alr family Thioredoxin PF00085.20 PSC72182.1 - 1.1e-18 67.1 0.0 2.2e-18 66.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin Trypsin_2 PF13365.6 PSC72182.1 - 5.1e-17 63.2 3.0 5.6e-17 63.0 0.2 2.4 1 1 1 2 2 2 1 Trypsin-like peptidase domain OST3_OST6 PF04756.13 PSC72182.1 - 3e-05 23.5 0.0 4.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Trypsin PF00089.26 PSC72182.1 - 8.2e-05 22.5 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 PSC72182.1 - 0.00034 20.9 0.0 0.0018 18.5 0.0 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 PSC72182.1 - 0.00071 19.4 0.1 0.0033 17.2 0.0 2.2 2 0 0 2 2 2 1 PDZ domain Thioredoxin_2 PF13098.6 PSC72182.1 - 0.0015 18.9 0.0 0.0039 17.6 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 PSC72182.1 - 0.0018 18.2 0.0 0.0045 16.9 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family Peptidase_S46 PF10459.9 PSC72182.1 - 0.0018 17.0 0.1 0.0028 16.4 0.1 1.1 1 0 0 1 1 1 1 Peptidase S46 Thioredoxin_8 PF13905.6 PSC72182.1 - 0.0025 18.1 0.0 0.0099 16.2 0.1 1.9 1 1 1 2 2 2 1 Thioredoxin-like Peptidase_S7 PF00949.21 PSC72182.1 - 0.0037 17.1 0.0 0.0077 16.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase S7, Flavivirus NS3 serine protease TraF PF13728.6 PSC72182.1 - 0.04 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 F plasmid transfer operon protein SUIM_assoc PF16619.5 PSC72182.1 - 0.04 14.0 0.3 0.096 12.8 0.3 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Peptidase_S29 PF02907.15 PSC72182.1 - 0.086 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Hepatitis C virus NS3 protease Thioredoxin_4 PF13462.6 PSC72182.1 - 0.11 12.7 0.1 0.38 10.9 0.1 1.9 1 0 0 1 1 1 0 Thioredoxin Redoxin PF08534.10 PSC72182.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Redoxin TamB PF04357.13 PSC72183.1 - 9.9e-25 87.6 0.0 1e-17 64.5 0.0 4.7 4 1 0 4 4 4 3 TamB, inner membrane protein subunit of TAM complex AsmA_2 PF13502.6 PSC72183.1 - 0.00023 20.7 4.1 1.2 8.6 0.0 6.1 5 1 1 6 6 6 2 AsmA-like C-terminal region DUF3971 PF13116.6 PSC72183.1 - 0.0037 16.9 0.0 0.14 11.7 0.0 3.1 3 0 0 3 3 3 1 Protein of unknown function AA_kinase PF00696.28 PSC72184.1 - 4.8e-45 154.0 0.0 7e-45 153.5 0.0 1.3 1 0 0 1 1 1 1 Amino acid kinase family ACT PF01842.25 PSC72184.1 - 2.7e-09 36.7 0.3 0.00043 20.0 0.2 2.7 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 PSC72184.1 - 1.1e-06 28.3 0.8 0.0027 17.5 0.0 2.4 2 0 0 2 2 2 2 ACT domain ACT_5 PF13710.6 PSC72184.1 - 0.051 13.4 1.6 0.56 10.1 0.2 2.7 2 0 0 2 2 2 0 ACT domain AP_endonuc_2 PF01261.24 PSC72188.1 - 0.08 12.4 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel Acyltransferase PF01553.21 PSC72189.1 - 6.9e-06 25.7 0.0 1.1e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase SUIM_assoc PF16619.5 PSC72190.1 - 0.022 14.8 2.6 0.046 13.8 2.6 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Pox_F17 PF04767.12 PSC72190.1 - 0.33 11.5 1.3 0.82 10.2 0.1 2.1 1 1 1 2 2 2 0 DNA-binding 11 kDa phosphoprotein MMR_HSR1 PF01926.23 PSC72191.1 - 3.3e-19 69.0 0.0 5e-19 68.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 PSC72191.1 - 4.8e-07 29.4 0.0 1.5e-06 27.9 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PSC72191.1 - 2e-05 24.5 0.0 0.0065 16.4 0.2 2.2 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 PSC72191.1 - 3.5e-05 23.9 0.7 0.00061 19.9 0.4 2.1 1 1 1 2 2 2 1 Dynamin family AIG1 PF04548.16 PSC72191.1 - 0.0017 17.7 0.0 0.0026 17.1 0.0 1.2 1 0 0 1 1 1 1 AIG1 family MeaB PF03308.16 PSC72191.1 - 0.01 14.8 0.1 0.063 12.3 0.1 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB GTP_EFTU PF00009.27 PSC72191.1 - 0.012 15.2 0.0 0.72 9.4 0.0 2.5 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain KH_2 PF07650.17 PSC72191.1 - 0.066 13.0 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 KH domain Cyt_b-c1_8 PF10890.8 PSC72192.1 - 1.6e-27 95.7 0.2 3e-27 94.8 0.2 1.5 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 ThiF PF00899.21 PSC72192.1 - 4.4e-21 75.3 0.1 6.5e-21 74.8 0.1 1.2 1 0 0 1 1 1 1 ThiF family UcrQ PF02939.16 PSC72192.1 - 0.00018 21.4 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 UcrQ family DUF3593 PF12159.8 PSC72193.1 - 1.7e-36 124.1 0.4 2.1e-36 123.8 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3593) SRP19 PF01922.17 PSC72194.1 - 1.2e-30 106.2 0.0 1.9e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 SRP19 protein K_channel_TID PF07941.11 PSC72194.1 - 0.74 10.3 7.9 1.4 9.5 7.9 1.6 1 1 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Glyco_hydro_14 PF01373.17 PSC72195.1 - 3.8e-105 352.1 0.0 1.1e-74 251.8 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 14 TPP_enzyme_N PF02776.18 PSC72195.1 - 0.09 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain AhpC-TSA_2 PF13911.6 PSC72197.1 - 8.4e-10 38.8 0.0 9.4e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Ifi-6-16 PF06140.13 PSC72197.1 - 0.067 13.1 0.2 0.21 11.5 0.0 1.9 2 0 0 2 2 2 0 Interferon-induced 6-16 family DNA_pol_A PF00476.20 PSC72198.1 - 5.2e-72 243.0 0.0 1.2e-70 238.5 0.0 2.6 2 1 0 2 2 2 1 DNA polymerase family A Kinesin PF00225.23 PSC72198.1 - 1.5e-37 129.3 0.0 3.7e-24 85.3 0.0 2.2 2 0 0 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 PSC72198.1 - 2e-18 66.8 0.0 1.1e-17 64.4 0.0 2.2 3 0 0 3 3 3 1 Microtubule binding DNA_pol_A_exo1 PF01612.20 PSC72198.1 - 2.1e-07 30.8 0.0 1.4e-06 28.1 0.0 2.4 1 1 0 1 1 1 1 3'-5' exonuclease zf-CCCH PF00642.24 PSC72199.1 - 6.6e-10 38.6 3.0 6.6e-10 38.6 3.0 1.7 2 0 0 2 2 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 PSC72199.1 - 1.8e-07 30.9 6.3 3.6e-07 29.9 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC72199.1 - 2.6e-07 30.5 9.9 4.4e-07 29.7 9.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 PSC72199.1 - 1.5e-05 25.2 8.9 3.1e-05 24.2 8.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf_CCCH_4 PF18345.1 PSC72199.1 - 1.9e-05 24.6 5.1 1.9e-05 24.6 5.1 1.8 2 0 0 2 2 1 1 Zinc finger domain zf-RING_10 PF16685.5 PSC72199.1 - 4.4e-05 23.5 4.2 4.4e-05 23.5 4.2 1.7 2 0 0 2 2 2 1 zinc RING finger of MSL2 zf-C3HC4 PF00097.25 PSC72199.1 - 0.00011 22.0 9.2 0.00022 21.0 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PSC72199.1 - 0.00038 20.2 9.2 0.00075 19.3 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC72199.1 - 0.0015 18.5 7.4 0.0031 17.5 7.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PSC72199.1 - 0.0059 16.4 7.3 0.011 15.6 7.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-P11 PF03854.14 PSC72199.1 - 0.033 13.9 3.7 0.057 13.1 3.7 1.3 1 0 0 1 1 1 0 P-11 zinc finger zf-C3HC4_4 PF15227.6 PSC72199.1 - 0.16 12.1 8.8 0.89 9.8 8.7 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-CCCH_4 PF18044.1 PSC72199.1 - 1.1 9.1 14.1 0.044 13.6 3.1 2.4 2 0 0 2 2 2 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 PSC72199.1 - 1.8 9.2 6.7 0.14 12.7 1.8 1.8 2 0 0 2 2 1 0 RNA-binding, Nab2-type zinc finger ISN1 PF06437.11 PSC72200.1 - 9e-94 314.7 0.0 1.2e-93 314.3 0.0 1.1 1 0 0 1 1 1 1 IMP-specific 5'-nucleotidase Hydrolase_3 PF08282.12 PSC72200.1 - 0.0011 18.7 0.0 0.79 9.4 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PSC72200.1 - 0.16 12.2 0.1 4.3 7.6 0.1 2.4 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ribosomal_L33 PF00471.20 PSC72201.1 - 3.7e-20 72.1 1.9 5.2e-20 71.6 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L33 Josephin PF02099.17 PSC72202.1 - 2e-17 63.8 0.1 7.5e-09 35.9 0.0 2.1 2 0 0 2 2 2 2 Josephin Histone PF00125.24 PSC72203.1 - 2.9e-54 183.0 1.9 3.2e-54 182.8 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 PSC72203.1 - 0.00013 22.5 1.7 0.00016 22.2 1.7 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 PSC72203.1 - 0.00045 20.5 0.0 0.00069 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 PSC72203.1 - 0.00049 20.2 0.5 0.00074 19.6 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 PSC72203.1 - 0.0052 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PSC72203.1 - 0.016 15.3 0.1 0.031 14.3 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit LMBR1 PF04791.16 PSC72204.1 - 3.4e-83 280.3 3.3 4.3e-83 280.0 3.3 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein RCC1 PF00415.18 PSC72205.1 - 2e-96 316.5 30.9 1.2e-15 57.9 0.3 8.1 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PSC72205.1 - 2.7e-46 154.5 42.4 1e-10 41.1 2.0 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat AAA PF00004.29 PSC72206.1 - 7.9e-94 311.1 0.0 7.4e-47 159.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Nucleolin_bd PF16725.5 PSC72206.1 - 1.3e-16 60.0 0.0 2.6e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Nucleolin binding domain AAA_lid_3 PF17862.1 PSC72206.1 - 1.4e-16 60.0 13.5 4.3e-09 36.0 0.3 3.5 4 0 0 4 4 3 2 AAA+ lid domain RuvB_N PF05496.12 PSC72206.1 - 1.7e-13 50.6 0.0 6.9e-07 29.2 0.0 3.0 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 PSC72206.1 - 4.8e-13 49.6 0.0 1.3e-05 25.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 PSC72206.1 - 1.8e-10 41.5 7.6 0.00023 21.6 0.1 5.1 3 2 1 4 4 3 2 AAA ATPase domain AAA_33 PF13671.6 PSC72206.1 - 1.9e-09 37.8 1.4 0.00024 21.3 0.0 3.1 4 0 0 4 4 2 2 AAA domain TIP49 PF06068.13 PSC72206.1 - 2.3e-09 36.9 0.0 8.2e-06 25.2 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_5 PF07728.14 PSC72206.1 - 3.9e-09 36.6 0.1 0.0025 17.8 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PSC72206.1 - 1.8e-08 34.8 2.9 0.11 12.8 0.0 4.9 3 2 2 5 5 4 2 AAA domain AAA_28 PF13521.6 PSC72206.1 - 1.6e-06 28.5 0.1 0.0045 17.2 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 PSC72206.1 - 2.1e-06 28.3 0.0 0.067 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 PSC72206.1 - 8.5e-06 25.8 0.0 0.14 12.1 0.0 2.2 2 0 0 2 2 2 2 Rad17 P-loop domain RNA_helicase PF00910.22 PSC72206.1 - 9.5e-06 26.0 0.0 0.067 13.6 0.0 2.7 3 0 0 3 3 2 2 RNA helicase AAA_14 PF13173.6 PSC72206.1 - 1e-05 25.6 0.0 0.13 12.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 PSC72206.1 - 1.2e-05 25.1 0.0 0.1 12.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Cytidylate_kin2 PF13189.6 PSC72206.1 - 1.3e-05 25.5 0.3 0.076 13.1 0.0 3.1 3 0 0 3 3 3 2 Cytidylate kinase-like family Mg_chelatase PF01078.21 PSC72206.1 - 3e-05 23.5 3.4 0.23 10.8 0.1 3.7 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 PSC72206.1 - 3e-05 23.4 0.1 0.16 11.2 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_3 PF07726.11 PSC72206.1 - 3.3e-05 23.7 0.0 0.011 15.6 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 PSC72206.1 - 3.8e-05 23.6 0.0 0.12 12.4 0.0 2.7 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain TsaE PF02367.17 PSC72206.1 - 5.8e-05 23.1 0.0 0.14 12.1 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_17 PF13207.6 PSC72206.1 - 0.00014 22.3 0.0 0.5 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 PSC72206.1 - 0.00019 21.4 0.1 0.07 13.0 0.0 3.7 4 0 0 4 4 3 1 NACHT domain ABC_tran PF00005.27 PSC72206.1 - 0.00022 21.7 0.0 0.61 10.6 0.0 3.0 3 0 0 3 3 2 1 ABC transporter Viral_helicase1 PF01443.18 PSC72206.1 - 0.00034 20.4 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 PSC72206.1 - 0.00036 20.2 7.1 2.6 7.6 0.3 4.4 2 2 1 4 4 4 1 AAA domain ATPase_2 PF01637.18 PSC72206.1 - 0.00065 19.7 0.0 0.23 11.3 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 PSC72206.1 - 0.0012 18.4 0.0 1.7 8.1 0.0 2.8 2 1 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 PSC72206.1 - 0.0022 18.1 0.1 1.9 8.6 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain ATPase PF06745.13 PSC72206.1 - 0.0028 17.1 0.3 3.9 6.8 0.0 3.2 2 1 1 3 3 3 1 KaiC DUF815 PF05673.13 PSC72206.1 - 0.003 16.8 0.0 2.7 7.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NB-ARC PF00931.22 PSC72206.1 - 0.0032 16.7 0.0 0.3 10.2 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Sigma54_activat PF00158.26 PSC72206.1 - 0.0032 17.2 0.0 3.6 7.2 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain PhoH PF02562.16 PSC72206.1 - 0.0095 15.4 0.6 1.8 8.0 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_24 PF13479.6 PSC72206.1 - 0.022 14.5 0.0 5.2 6.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 PSC72206.1 - 0.028 14.5 0.0 8.7 6.4 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase Parvo_NS1 PF01057.17 PSC72206.1 - 0.04 13.0 0.9 0.49 9.4 0.0 2.4 3 0 0 3 3 2 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 PSC72206.1 - 0.045 14.1 1.7 7.7 6.8 0.1 2.7 2 1 0 2 2 2 0 AAA domain CPT PF07931.12 PSC72206.1 - 0.09 12.6 0.0 0.63 9.9 0.0 2.4 3 0 0 3 3 2 0 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.15 PSC72206.1 - 0.19 11.6 0.0 4.6 7.1 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_11 PF13086.6 PSC72206.1 - 0.21 11.3 4.1 3 7.6 0.0 3.0 4 0 0 4 4 3 0 AAA domain Hydin_ADK PF17213.3 PSC72206.1 - 0.41 10.9 0.0 0.41 10.9 0.0 4.1 5 0 0 5 5 4 0 Hydin Adenylate kinase-like domain ESR1_C PF12743.7 PSC72206.1 - 1.4 8.8 0.0 1.4 8.8 0.0 4.2 4 0 0 4 4 4 0 Oestrogen-type nuclear receptor final C-terminal Serglycin PF04360.12 PSC72206.1 - 2.7 7.9 5.3 14 5.6 2.9 2.7 2 0 0 2 2 2 0 Serglycin AAA PF00004.29 PSC72207.1 - 7.9e-94 311.1 0.0 7.4e-47 159.1 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Nucleolin_bd PF16725.5 PSC72207.1 - 1.3e-16 60.0 0.0 2.6e-16 59.0 0.0 1.4 1 0 0 1 1 1 1 Nucleolin binding domain AAA_lid_3 PF17862.1 PSC72207.1 - 1.4e-16 60.0 13.5 4.3e-09 36.0 0.3 3.5 4 0 0 4 4 3 2 AAA+ lid domain RuvB_N PF05496.12 PSC72207.1 - 1.8e-13 50.6 0.0 6.8e-07 29.2 0.0 3.0 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 PSC72207.1 - 4.6e-13 49.6 0.0 1.3e-05 25.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_33 PF13671.6 PSC72207.1 - 8.8e-10 38.9 0.1 0.00024 21.3 0.0 3.0 3 0 0 3 3 2 2 AAA domain TIP49 PF06068.13 PSC72207.1 - 2.3e-09 36.9 0.0 8.2e-06 25.2 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_16 PF13191.6 PSC72207.1 - 2.5e-09 37.8 12.3 0.00023 21.6 0.1 5.4 4 2 1 5 5 4 2 AAA ATPase domain AAA_5 PF07728.14 PSC72207.1 - 3.9e-09 36.6 0.1 0.0025 17.8 0.0 3.8 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PSC72207.1 - 1.8e-08 34.8 2.9 0.11 12.8 0.0 4.9 3 2 2 5 5 4 2 AAA domain AAA_18 PF13238.6 PSC72207.1 - 2.1e-06 28.3 0.0 0.067 13.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 PSC72207.1 - 7.1e-06 26.3 2.3 0.0045 17.2 0.0 3.2 4 0 0 4 4 2 1 AAA domain Rad17 PF03215.15 PSC72207.1 - 8.3e-06 25.8 0.0 0.14 12.1 0.0 2.3 2 0 0 2 2 2 2 Rad17 P-loop domain RNA_helicase PF00910.22 PSC72207.1 - 9.8e-06 25.9 0.0 0.067 13.6 0.0 2.7 3 0 0 3 3 2 2 RNA helicase AAA_14 PF13173.6 PSC72207.1 - 1e-05 25.6 0.0 0.13 12.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.17 PSC72207.1 - 1.2e-05 25.1 0.0 0.1 12.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein Cytidylate_kin2 PF13189.6 PSC72207.1 - 2.2e-05 24.7 0.0 0.076 13.1 0.0 2.7 2 0 0 2 2 2 2 Cytidylate kinase-like family Zeta_toxin PF06414.12 PSC72207.1 - 2.9e-05 23.4 0.1 0.16 11.2 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin AAA_3 PF07726.11 PSC72207.1 - 3.3e-05 23.8 0.0 0.011 15.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 PSC72207.1 - 3.8e-05 23.6 0.0 0.12 12.4 0.0 2.7 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain TsaE PF02367.17 PSC72207.1 - 5.8e-05 23.1 0.0 0.14 12.1 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 PSC72207.1 - 9.9e-05 21.8 4.1 0.23 10.8 0.1 3.5 4 0 0 4 4 3 2 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 PSC72207.1 - 0.00014 22.3 0.0 0.5 10.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 PSC72207.1 - 0.00019 21.4 0.1 0.07 13.0 0.0 3.7 4 0 0 4 4 3 1 NACHT domain ABC_tran PF00005.27 PSC72207.1 - 0.00023 21.7 0.0 0.61 10.6 0.0 2.9 3 0 0 3 3 2 1 ABC transporter Viral_helicase1 PF01443.18 PSC72207.1 - 0.00034 20.4 0.0 0.14 11.9 0.0 2.2 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 PSC72207.1 - 0.00035 20.2 7.1 2.6 7.6 0.3 4.4 2 2 1 4 4 4 1 AAA domain ATPase_2 PF01637.18 PSC72207.1 - 0.00064 19.7 0.0 0.23 11.3 0.0 2.5 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 PSC72207.1 - 0.0012 18.4 0.0 1.7 8.2 0.0 2.8 2 1 0 2 2 2 1 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 PSC72207.1 - 0.0022 18.1 0.1 1.9 8.6 0.0 3.0 3 0 0 3 3 3 1 Sigma-54 interaction domain ATPase PF06745.13 PSC72207.1 - 0.0028 17.0 0.3 3.9 6.8 0.0 3.2 2 1 1 3 3 3 1 KaiC DUF815 PF05673.13 PSC72207.1 - 0.003 16.8 0.0 2.7 7.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NB-ARC PF00931.22 PSC72207.1 - 0.0031 16.7 0.0 0.3 10.2 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Sigma54_activat PF00158.26 PSC72207.1 - 0.0032 17.2 0.0 3.6 7.2 0.0 3.0 2 1 0 2 2 2 1 Sigma-54 interaction domain PhoH PF02562.16 PSC72207.1 - 0.0093 15.4 0.6 1.8 8.0 0.1 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_11 PF13086.6 PSC72207.1 - 0.016 15.1 0.1 3 7.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 PSC72207.1 - 0.022 14.5 0.0 5.2 6.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain SKI PF01202.22 PSC72207.1 - 0.028 14.5 0.0 8.7 6.4 0.0 2.7 2 0 0 2 2 2 0 Shikimate kinase Parvo_NS1 PF01057.17 PSC72207.1 - 0.036 13.2 0.7 0.49 9.4 0.0 2.4 3 0 0 3 3 2 0 Parvovirus non-structural protein NS1 AAA_19 PF13245.6 PSC72207.1 - 0.045 14.1 1.7 7.7 6.8 0.1 2.7 2 1 0 2 2 2 0 AAA domain CPT PF07931.12 PSC72207.1 - 0.09 12.6 0.0 0.63 9.9 0.0 2.4 3 0 0 3 3 2 0 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.15 PSC72207.1 - 0.19 11.6 0.0 4.5 7.1 0.0 2.4 2 0 0 2 2 2 0 NTPase Hydin_ADK PF17213.3 PSC72207.1 - 0.41 10.9 0.0 0.41 10.9 0.0 4.1 5 0 0 5 5 4 0 Hydin Adenylate kinase-like domain ESR1_C PF12743.7 PSC72207.1 - 1.4 8.8 0.0 1.4 8.8 0.0 4.2 4 0 0 4 4 4 0 Oestrogen-type nuclear receptor final C-terminal Pro_isomerase PF00160.21 PSC72208.1 - 2.3e-36 125.5 0.0 3e-36 125.1 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AP2 PF00847.20 PSC72208.1 - 0.055 13.7 0.2 0.15 12.3 0.0 1.8 2 0 0 2 2 2 0 AP2 domain Histone PF00125.24 PSC72209.1 - 8.6e-16 58.5 0.0 1.1e-15 58.2 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC72209.1 - 0.0078 16.5 0.1 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DnaJ PF00226.31 PSC72209.1 - 0.052 13.7 0.0 0.11 12.7 0.0 1.6 1 1 0 1 1 1 0 DnaJ domain RP-C PF03428.13 PSC72209.1 - 0.076 12.7 0.4 4.1 7.0 0.0 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain Histone_H2A_C PF16211.5 PSC72210.1 - 1.6e-20 72.5 2.1 3.3e-20 71.5 2.1 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 PSC72210.1 - 1.8e-15 57.4 0.0 2.3e-15 57.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC72210.1 - 1.5e-05 25.1 0.0 2.4e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase_Tyr PF07714.17 PSC72211.1 - 9.5e-50 169.3 0.0 1.2e-49 168.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC72211.1 - 1.2e-46 159.2 0.0 1.7e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Ctf8 PF09696.10 PSC72211.1 - 4e-10 40.2 1.1 4.1e-08 33.7 0.0 3.4 2 2 0 2 2 2 1 Ctf8 APH PF01636.23 PSC72211.1 - 0.00072 19.5 0.0 0.00072 19.5 0.0 3.5 3 1 1 4 4 3 1 Phosphotransferase enzyme family TRAF_BIRC3_bd PF16673.5 PSC72211.1 - 0.0028 17.4 0.2 0.0063 16.3 0.2 1.6 1 0 0 1 1 1 1 TNF receptor-associated factor BIRC3 binding domain Pkinase_fungal PF17667.1 PSC72211.1 - 0.013 14.3 0.0 0.023 13.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase YukC PF10140.9 PSC72211.1 - 0.013 14.3 0.0 0.02 13.7 0.0 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC Herpes_UL6 PF01763.16 PSC72211.1 - 0.023 13.2 0.1 0.033 12.7 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Haspin_kinase PF12330.8 PSC72211.1 - 0.029 13.3 0.0 0.042 12.8 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Kdo PF06293.14 PSC72211.1 - 0.073 12.4 0.0 0.22 10.9 0.0 1.7 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ZapB PF06005.12 PSC72211.1 - 0.52 10.8 3.6 0.5 10.8 0.8 2.3 1 1 0 1 1 1 0 Cell division protein ZapB DUF4407 PF14362.6 PSC72211.1 - 3 7.1 11.9 4.6 6.5 11.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ctr PF04145.15 PSC72212.1 - 0.77 10.4 3.1 25 5.4 1.1 2.5 1 1 1 2 2 2 0 Ctr copper transporter family TMP_2 PF06791.13 PSC72212.1 - 1.2 8.7 6.8 0.74 9.5 4.2 1.8 1 1 0 1 1 1 0 Prophage tail length tape measure protein Ribosomal_L3 PF00297.22 PSC72213.1 - 1.4e-19 70.4 2.7 2.6e-17 62.9 2.7 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 LIAS_N PF16881.5 PSC72214.1 - 1.7e-15 57.4 0.0 4.1e-15 56.1 0.0 1.7 1 0 0 1 1 1 1 N-terminal domain of lipoyl synthase of Radical_SAM family Radical_SAM PF04055.21 PSC72214.1 - 1.9e-14 54.4 0.0 5e-14 53.0 0.0 1.7 1 1 1 2 2 2 1 Radical SAM superfamily NIL PF09383.10 PSC72214.1 - 0.0095 15.8 0.0 0.024 14.5 0.0 1.6 1 0 0 1 1 1 1 NIL domain Trans_reg_C PF00486.28 PSC72214.1 - 0.17 12.0 0.0 0.36 11.0 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulatory protein, C terminal Glyco_hydro_3_C PF01915.22 PSC72215.1 - 1.8e-44 152.2 0.0 2.5e-44 151.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 PSC72215.1 - 2.7e-41 142.0 0.0 4.6e-41 141.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain LRR_8 PF13855.6 PSC72216.1 - 4e-09 36.1 8.5 1.3e-05 24.9 1.7 2.3 1 1 2 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 PSC72216.1 - 2.1e-08 34.3 1.8 0.0006 20.2 0.1 3.2 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PSC72216.1 - 2.9e-06 26.9 0.0 4e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 Leucine-rich repeat LRR_6 PF13516.6 PSC72216.1 - 0.0058 16.6 1.9 31 5.0 0.0 4.4 5 0 0 5 5 5 1 Leucine Rich repeat SAPS PF04499.15 PSC72216.1 - 0.25 10.1 13.2 0.34 9.6 13.2 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein XRN_M PF17846.1 PSC72218.1 - 2.4e-146 488.2 0.5 1.7e-108 363.4 0.0 2.6 3 0 0 3 3 3 2 Xrn1 helical domain XRN_N PF03159.18 PSC72218.1 - 8.9e-102 339.6 0.7 1.4e-101 338.9 0.0 1.7 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus 2OG-FeII_Oxy_2 PF13532.6 PSC72219.1 - 8.5e-19 68.5 0.0 3.7e-17 63.2 0.0 2.9 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Methyltransf_25 PF13649.6 PSC72219.1 - 9e-12 45.6 0.3 2.2e-11 44.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC72219.1 - 1.2e-11 45.1 0.0 2.8e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC72219.1 - 3.8e-07 30.8 0.0 1.1e-06 29.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC72219.1 - 7.5e-06 25.9 0.1 2.3e-05 24.3 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC72219.1 - 1e-05 25.4 0.0 1.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CCDC53 PF10152.9 PSC72219.1 - 0.016 15.6 6.8 0.14 12.5 1.5 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Methyltransf_9 PF08003.11 PSC72219.1 - 0.036 13.0 0.0 0.082 11.8 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 PSC72219.1 - 0.09 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family TFIIA PF03153.13 PSC72219.1 - 1.5 8.8 15.4 3.8 7.4 7.9 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DHBP_synthase PF00926.19 PSC72220.1 - 6e-84 280.4 0.1 9.3e-84 279.7 0.1 1.3 1 0 0 1 1 1 1 3,4-dihydroxy-2-butanone 4-phosphate synthase GTP_cyclohydro2 PF00925.20 PSC72220.1 - 1.6e-52 177.4 0.0 3.4e-52 176.3 0.0 1.5 2 0 0 2 2 2 1 GTP cyclohydrolase II Macoilin PF09726.9 PSC72220.1 - 0.17 10.4 0.2 0.21 10.1 0.2 1.1 1 0 0 1 1 1 0 Macoilin family Histone PF00125.24 PSC72221.1 - 2.9e-14 53.6 0.0 4.6e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 PSC72221.1 - 7.4e-13 48.0 0.4 1.5e-12 47.0 0.4 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 PSC72221.1 - 0.00019 21.7 0.0 0.00036 20.8 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Phosphodiest PF01663.22 PSC72222.1 - 1.2e-08 35.0 1.7 1e-07 31.9 0.3 2.0 1 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 PSC72222.1 - 0.0083 15.5 0.0 0.31 10.4 0.0 2.4 2 0 0 2 2 2 2 Sulfatase MID_MedPIWI PF18296.1 PSC72225.1 - 3e-07 30.5 4.6 2.2e-05 24.4 4.6 3.5 1 1 0 1 1 1 1 MID domain of medPIWI NAC PF01849.18 PSC72226.1 - 3e-24 84.8 0.9 3e-24 84.8 0.9 2.0 3 0 0 3 3 3 1 NAC domain GST_C_4 PF14834.6 PSC72226.1 - 0.09 13.2 0.2 0.16 12.3 0.2 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain PBP1_TM PF14812.6 PSC72226.1 - 2.2 8.7 6.6 2.1 8.8 4.7 1.8 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pes-10 PF07149.11 PSC72226.1 - 5.1 6.1 6.2 11 5.0 0.3 2.2 2 0 0 2 2 2 0 Pes-10 PGA2 PF07543.12 PSC72226.1 - 7.1 6.6 7.9 2.2 8.2 2.5 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 Reticulon PF02453.17 PSC72227.1 - 2e-38 131.8 0.0 2.4e-38 131.5 0.0 1.1 1 0 0 1 1 1 1 Reticulon Herpes_UL49_5 PF05702.11 PSC72227.1 - 0.12 12.5 0.3 0.28 11.3 0.3 1.5 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Memo PF01875.17 PSC72228.1 - 2.1e-79 266.5 0.0 2.4e-79 266.3 0.0 1.0 1 0 0 1 1 1 1 Memo-like protein Radical_SAM PF04055.21 PSC72230.1 - 3.4e-22 79.6 0.0 1.4e-12 48.3 0.0 2.4 2 0 0 2 2 2 2 Radical SAM superfamily Trypsin PF00089.26 PSC72230.1 - 4.3e-19 69.2 0.2 1.6e-18 67.3 0.0 2.2 2 0 0 2 2 2 1 Trypsin Cyclin_N PF00134.23 PSC72230.1 - 1.1e-11 44.6 0.0 1.1e-11 44.6 0.0 2.3 2 0 0 2 2 1 1 Cyclin, N-terminal domain Presenilin PF01080.17 PSC72230.1 - 0.022 13.5 11.8 0.036 12.8 11.8 1.2 1 0 0 1 1 1 0 Presenilin MDM10 PF12519.8 PSC72230.1 - 0.42 9.4 2.7 0.67 8.8 2.7 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Gti1_Pac2 PF09729.9 PSC72230.1 - 0.64 10.1 5.8 1.3 9.1 5.8 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family CCSAP PF15748.5 PSC72230.1 - 0.95 9.6 14.0 0.59 10.3 5.6 2.4 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated DUF2828 PF11443.8 PSC72230.1 - 2 6.4 5.7 3.2 5.7 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CobT PF06213.12 PSC72230.1 - 3.3 7.0 22.7 0.09 12.2 12.2 2.2 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT SLC12 PF03522.15 PSC72230.1 - 3.9 6.4 7.8 6.2 5.7 7.8 1.2 1 0 0 1 1 1 0 Solute carrier family 12 SpoIIP PF07454.11 PSC72230.1 - 4 6.8 12.3 0.42 10.0 7.3 1.7 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) CPSF100_C PF13299.6 PSC72230.1 - 4.8 7.3 10.2 4.6 7.4 5.6 2.7 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal DUF5427 PF10310.9 PSC72230.1 - 5.1 5.9 15.7 0.13 11.2 8.3 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5427) DUF2722 PF10846.8 PSC72230.1 - 8.5 5.2 38.8 2.8 6.8 28.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) PAP_assoc PF03828.19 PSC72231.1 - 1.2e-17 63.9 0.0 2.6e-17 62.8 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 PSC72231.1 - 0.0014 18.9 0.0 0.0026 18.0 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyltransferase domain LMWPc PF01451.21 PSC72231.1 - 0.035 14.5 0.0 0.12 12.7 0.0 1.9 1 0 0 1 1 1 0 Low molecular weight phosphotyrosine protein phosphatase TRAM_LAG1_CLN8 PF03798.16 PSC72232.1 - 3.2e-07 30.3 4.6 4.2e-07 29.9 4.6 1.1 1 0 0 1 1 1 1 TLC domain Exostosin PF03016.15 PSC72233.1 - 2e-29 102.8 5.4 5e-29 101.5 0.0 3.1 2 1 0 2 2 2 1 Exostosin family TFIIA PF03153.13 PSC72233.1 - 0.0022 18.1 50.4 0.1 12.6 11.4 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit SpoIIP PF07454.11 PSC72233.1 - 0.0029 17.1 3.9 0.0029 17.1 3.9 1.9 2 0 0 2 2 2 1 Stage II sporulation protein P (SpoIIP) EPL1 PF10513.9 PSC72233.1 - 0.0044 17.4 4.1 0.0044 17.4 4.1 2.3 2 0 0 2 2 2 1 Enhancer of polycomb-like Connexin PF00029.19 PSC72233.1 - 0.0056 16.5 1.9 0.0056 16.5 1.9 1.5 2 0 0 2 2 2 1 Connexin Striatin PF08232.12 PSC72233.1 - 0.13 12.9 17.3 0.32 11.6 6.6 2.4 2 0 0 2 2 2 0 Striatin family EGF_2 PF07974.13 PSC72233.1 - 0.14 12.5 6.0 0.52 10.7 6.0 2.1 1 0 0 1 1 1 0 EGF-like domain 60KD_IMP PF02096.20 PSC72233.1 - 0.18 11.7 7.3 0.37 10.7 7.3 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein OATP PF03137.20 PSC72233.1 - 0.34 9.1 2.2 0.51 8.6 2.2 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family EMC3_TMCO1 PF01956.16 PSC72233.1 - 0.34 10.6 4.3 0.67 9.7 4.3 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF2722 PF10846.8 PSC72233.1 - 0.62 8.9 35.6 0.017 14.1 23.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) EGF_alliinase PF04863.13 PSC72233.1 - 0.69 10.4 6.5 2.1 8.8 6.5 1.9 1 0 0 1 1 1 0 Alliinase EGF-like domain DUF4770 PF15994.5 PSC72233.1 - 1 9.6 17.2 0.037 14.3 9.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) DUF4045 PF13254.6 PSC72233.1 - 1.3 8.6 21.5 0.62 9.7 5.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Suf PF05843.14 PSC72233.1 - 1.4 8.9 22.8 0.067 13.2 9.0 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) CLN3 PF02487.17 PSC72233.1 - 1.5 7.8 6.3 2.7 6.9 6.3 1.3 1 0 0 1 1 1 0 CLN3 protein CDC45 PF02724.14 PSC72233.1 - 1.7 6.8 12.4 0.13 10.6 5.5 1.9 2 0 0 2 2 2 0 CDC45-like protein Pex14_N PF04695.13 PSC72233.1 - 1.9 9.1 37.2 0.27 11.9 17.5 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ALMT PF11744.8 PSC72233.1 - 2 7.2 8.1 4 6.1 8.1 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3408 PF11888.8 PSC72233.1 - 2.5 8.2 21.5 0.093 12.9 10.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF3801 PF12687.7 PSC72233.1 - 3 7.9 17.9 0.38 10.8 5.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) Rxt3 PF08642.10 PSC72233.1 - 8.5 7.2 9.5 0.4 11.5 2.9 2.0 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Exostosin PF03016.15 PSC72234.1 - 2e-29 102.8 5.4 5e-29 101.5 0.0 3.1 2 1 0 2 2 2 1 Exostosin family SpoIIP PF07454.11 PSC72234.1 - 0.0029 17.1 3.9 0.0029 17.1 3.9 1.8 2 0 0 2 2 2 1 Stage II sporulation protein P (SpoIIP) EPL1 PF10513.9 PSC72234.1 - 0.0044 17.4 4.1 0.0044 17.4 4.1 2.2 2 0 0 2 2 2 1 Enhancer of polycomb-like TFIIA PF03153.13 PSC72234.1 - 0.0045 17.0 50.4 0.2 11.6 11.3 2.1 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Connexin PF00029.19 PSC72234.1 - 0.0056 16.5 1.9 0.0056 16.5 1.9 1.5 2 0 0 2 2 2 1 Connexin Striatin PF08232.12 PSC72234.1 - 0.13 12.9 17.3 0.32 11.6 6.6 2.4 2 0 0 2 2 2 0 Striatin family EGF_2 PF07974.13 PSC72234.1 - 0.14 12.5 6.0 0.52 10.7 6.0 2.1 1 0 0 1 1 1 0 EGF-like domain 60KD_IMP PF02096.20 PSC72234.1 - 0.18 11.7 7.3 0.37 10.7 7.3 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein OATP PF03137.20 PSC72234.1 - 0.34 9.2 2.2 0.51 8.6 2.2 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family EMC3_TMCO1 PF01956.16 PSC72234.1 - 0.34 10.6 4.3 0.67 9.7 4.3 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF2722 PF10846.8 PSC72234.1 - 0.62 8.9 35.6 0.017 14.1 23.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) EGF_alliinase PF04863.13 PSC72234.1 - 0.69 10.4 6.5 2.1 8.8 6.5 1.9 1 0 0 1 1 1 0 Alliinase EGF-like domain Suf PF05843.14 PSC72234.1 - 0.74 9.7 21.9 0.066 13.2 9.0 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4770 PF15994.5 PSC72234.1 - 0.79 9.9 16.7 0.037 14.3 9.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) CDC45 PF02724.14 PSC72234.1 - 1.3 7.2 11.9 0.13 10.6 5.5 1.9 2 0 0 2 2 2 0 CDC45-like protein CLN3 PF02487.17 PSC72234.1 - 1.5 7.8 6.3 2.7 6.9 6.3 1.3 1 0 0 1 1 1 0 CLN3 protein ALMT PF11744.8 PSC72234.1 - 2 7.2 8.1 4 6.1 8.1 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Pex14_N PF04695.13 PSC72234.1 - 2 9.1 37.2 0.27 11.9 17.5 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3801 PF12687.7 PSC72234.1 - 2.6 8.1 17.5 0.38 10.8 5.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) DUF3408 PF11888.8 PSC72234.1 - 2.9 8.0 21.6 0.093 12.9 10.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) TERB2 PF15101.6 PSC72234.1 - 7.5 6.6 25.1 0.68 10.0 17.6 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Rxt3 PF08642.10 PSC72234.1 - 8.5 7.2 9.5 0.4 11.5 2.9 2.0 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 CCSAP PF15748.5 PSC72234.1 - 9.6 6.3 26.8 0.077 13.2 7.7 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated SpoU_methylase PF00588.19 PSC72235.1 - 6e-22 78.3 0.0 1.1e-09 38.7 0.0 2.2 2 0 0 2 2 2 2 SpoU rRNA Methylase family Methyltrn_RNA_4 PF09936.9 PSC72235.1 - 0.016 15.1 0.0 0.04 13.8 0.0 1.6 2 0 0 2 2 2 0 SAM-dependent RNA methyltransferase UDPG_MGDP_dh_C PF03720.15 PSC72235.1 - 0.028 14.8 0.0 0.078 13.4 0.0 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain RNA_pol_Rpb1_5 PF04998.17 PSC72236.1 - 8.5e-105 350.0 0.0 1.4e-104 349.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 PSC72236.1 - 1.9e-101 339.5 0.0 4.2e-101 338.4 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 PSC72236.1 - 4e-69 232.1 0.7 2e-68 229.8 0.0 2.2 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 PSC72236.1 - 1.4e-55 188.1 0.0 2.6e-55 187.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_7 PF04990.12 PSC72236.1 - 6.4e-50 168.6 1.6 1.3e-49 167.6 1.6 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_3 PF04983.18 PSC72236.1 - 1.4e-46 158.3 0.0 3e-46 157.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 PSC72236.1 - 1.3e-39 134.4 1.5 3.7e-39 133.0 1.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 PSC72236.1 - 3.7e-35 118.4 275.9 0.0019 18.4 11.9 16.7 5 2 9 21 21 21 18 RNA polymerase Rpb1 C-terminal repeat TACC_C PF05010.14 PSC72236.1 - 0.19 11.5 1.6 0.35 10.6 1.6 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Adaptin_binding PF10199.9 PSC72238.1 - 7.4e-16 58.8 0.4 1.2e-15 58.1 0.4 1.3 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 Dus PF01207.17 PSC72239.1 - 1.9e-54 184.8 0.0 1.9e-48 165.2 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) SNARE PF05739.19 PSC72240.1 - 0.0014 18.5 0.9 0.0038 17.2 0.9 1.8 1 0 0 1 1 1 1 SNARE domain Syntaxin-6_N PF09177.11 PSC72240.1 - 0.014 16.0 1.5 0.014 16.0 1.5 2.8 2 2 0 2 2 2 0 Syntaxin 6, N-terminal EMP24_GP25L PF01105.24 PSC72240.1 - 0.24 11.3 2.6 0.33 10.9 0.1 2.1 2 0 0 2 2 2 0 emp24/gp25L/p24 family/GOLD RecG_N PF17190.4 PSC72240.1 - 0.58 10.9 3.5 5.1 7.9 0.8 2.6 2 1 0 2 2 2 0 RecG N-terminal helical domain TMPIT PF07851.13 PSC72240.1 - 1 8.6 4.7 1.1 8.5 0.1 2.1 2 0 0 2 2 2 0 TMPIT-like protein XhlA PF10779.9 PSC72240.1 - 2.1 8.6 7.7 3 8.1 1.9 2.9 2 1 1 3 3 3 0 Haemolysin XhlA DUF16 PF01519.16 PSC72240.1 - 2.6 8.6 8.2 0.26 11.8 0.8 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF16 Nup54 PF13874.6 PSC72240.1 - 3.7 7.7 9.3 0.21 11.7 0.7 2.3 2 1 0 2 2 2 0 Nucleoporin complex subunit 54 MCPsignal PF00015.21 PSC72240.1 - 4 7.2 6.3 18 5.1 0.8 2.6 2 2 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain SKA2 PF16740.5 PSC72240.1 - 5 6.9 9.4 1 9.2 1.9 2.6 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Orai-1 PF07856.12 PSC72241.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Mediator of CRAC channel activity JAB PF01398.21 PSC72242.1 - 1.8e-10 40.8 0.0 3.5e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease eIF2_C PF09173.11 PSC72243.1 - 2.1e-36 124.0 0.9 4.9e-36 122.8 0.2 2.0 2 0 0 2 2 2 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 PSC72243.1 - 1.2e-24 86.9 0.6 1e-23 83.9 0.6 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 PSC72243.1 - 1.8e-10 41.0 2.2 2.6e-10 40.5 0.8 2.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 PSC72243.1 - 0.00026 20.9 0.3 0.0032 17.4 0.0 2.1 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 PSC72243.1 - 0.0097 16.0 0.0 0.019 15.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 PSC72243.1 - 0.14 12.2 0.2 0.62 10.1 0.1 1.9 1 1 0 2 2 2 0 Dynamin family DA1-like PF12315.8 PSC72244.1 - 3.9e-50 170.1 0.1 3.6e-48 163.7 0.1 2.4 1 1 0 1 1 1 1 Protein DA1 LIM PF00412.22 PSC72244.1 - 5.7e-09 36.1 4.2 5.2e-08 33.0 0.0 3.1 1 1 1 3 3 3 2 LIM domain Cupin_8 PF13621.6 PSC72245.1 - 4.7e-13 49.4 0.0 8.5e-13 48.6 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain Castor_Poll_mid PF06241.12 PSC72245.1 - 3.1e-10 40.0 0.0 2.1e-08 34.1 0.0 3.1 2 0 0 2 2 2 1 Castor and Pollux, part of voltage-gated ion channel SUIM_assoc PF16619.5 PSC72245.1 - 0.04 14.0 3.1 0.098 12.7 3.1 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TOBE_3 PF12857.7 PSC72245.1 - 0.044 13.7 0.1 0.23 11.4 0.1 2.3 1 0 0 1 1 1 0 TOBE-like domain TrkA_N PF02254.18 PSC72245.1 - 0.17 12.1 0.0 2.3 8.5 0.0 2.4 2 0 0 2 2 2 0 TrkA-N domain Kelch_4 PF13418.6 PSC72246.1 - 1e-26 92.6 6.1 1.2e-07 31.6 0.0 6.2 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 PSC72246.1 - 5.5e-23 80.5 0.2 0.0043 17.0 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 PSC72246.1 - 2.5e-13 49.8 0.1 0.00088 19.5 0.0 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_3 PF13415.6 PSC72246.1 - 1.5e-12 47.4 15.5 0.00085 19.5 0.0 7.7 8 1 0 8 8 8 3 Galactose oxidase, central domain Kelch_2 PF07646.15 PSC72246.1 - 3.6e-11 42.6 2.8 0.066 13.2 0.1 5.5 6 0 0 6 6 6 3 Kelch motif Kelch_1 PF01344.25 PSC72246.1 - 3e-06 26.7 6.5 0.099 12.2 0.1 5.6 6 0 0 6 6 6 3 Kelch motif CCDC53 PF10152.9 PSC72246.1 - 0.29 11.6 2.6 0.22 11.9 0.7 1.7 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DUF2076 PF09849.9 PSC72246.1 - 1.5 8.8 13.6 0.26 11.3 8.5 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) SCO1-SenC PF02630.14 PSC72247.1 - 2.1e-48 163.6 0.0 3e-48 163.1 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC AhpC-TSA PF00578.21 PSC72247.1 - 1.2e-06 28.5 0.0 2.1e-06 27.6 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 PSC72247.1 - 0.00038 20.7 0.0 0.00062 20.1 0.0 1.5 1 1 0 1 1 1 1 Thioredoxin-like Ribosomal_S24e PF01282.19 PSC72248.1 - 3.2e-37 126.3 0.0 4.9e-37 125.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S24e T3SSipB PF16535.5 PSC72249.1 - 4.6e-05 24.0 18.8 0.00024 21.6 8.4 2.3 2 0 0 2 2 2 2 Type III cell invasion protein SipB IFT57 PF10498.9 PSC72249.1 - 0.087 11.8 0.3 0.19 10.6 0.1 1.6 2 0 0 2 2 2 0 Intra-flagellar transport protein 57 Syntaxin PF00804.25 PSC72249.1 - 0.14 11.8 1.6 0.76 9.4 0.2 2.1 2 0 0 2 2 2 0 Syntaxin IMD PF08397.11 PSC72249.1 - 0.22 10.9 1.7 5.8 6.2 0.1 2.2 2 0 0 2 2 2 0 IRSp53/MIM homology domain Nup54 PF13874.6 PSC72249.1 - 0.29 11.2 5.0 0.072 13.2 1.3 1.9 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Tropomyosin PF00261.20 PSC72249.1 - 0.33 10.3 6.0 0.12 11.8 2.1 2.0 2 0 0 2 2 2 0 Tropomyosin APG6_N PF17675.1 PSC72249.1 - 1 9.9 5.5 13 6.3 0.1 2.6 2 1 1 3 3 3 0 Apg6 coiled-coil region CENP-H PF05837.12 PSC72249.1 - 1.6 9.2 7.0 0.67 10.4 2.5 2.5 2 2 0 2 2 2 0 Centromere protein H (CENP-H) CRISPR_Cse1 PF09481.10 PSC72249.1 - 5.4 6.0 10.1 0.55 9.3 2.3 2.0 2 0 0 2 2 2 0 CRISPR-associated protein Cse1 (CRISPR_cse1) CLZ PF16526.5 PSC72249.1 - 9.8 6.6 6.6 1.6 9.2 0.3 2.7 4 0 0 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels RF-1 PF00472.20 PSC72250.1 - 1.4e-22 79.8 6.2 2.1e-22 79.2 6.2 1.2 1 0 0 1 1 1 1 RF-1 domain zf-ZPR1 PF03367.13 PSC72250.1 - 0.07 13.0 1.3 0.1 12.4 1.3 1.3 1 1 0 1 1 1 0 ZPR1 zinc-finger domain TraF_2 PF13729.6 PSC72250.1 - 0.098 12.0 1.4 0.24 10.7 0.7 1.8 1 1 1 2 2 2 0 F plasmid transfer operon, TraF, protein FapA PF03961.13 PSC72250.1 - 0.25 9.9 4.7 0.31 9.6 4.7 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Sec7 PF01369.20 PSC72251.1 - 2.6e-74 248.9 0.1 4.7e-74 248.0 0.1 1.4 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 PSC72251.1 - 7.4e-41 139.7 0.1 3.8e-40 137.4 0.0 2.3 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 PSC72251.1 - 2.7e-32 110.5 0.9 3.5e-31 106.9 0.1 3.5 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) DCB PF16213.5 PSC72251.1 - 8.7e-26 90.7 0.1 1.1e-23 83.9 0.0 3.4 3 0 0 3 3 3 1 Dimerisation and cyclophilin-binding domain of Mon2 Mon2_C PF16206.5 PSC72251.1 - 2.6e-08 32.5 0.0 5.7e-08 31.4 0.0 1.5 2 0 0 2 2 2 1 C-terminal region of Mon2 protein HEAT PF02985.22 PSC72251.1 - 0.011 15.9 1.6 11 6.6 0.0 5.2 5 0 0 5 5 5 0 HEAT repeat Ank_2 PF12796.7 PSC72252.1 - 3.4e-22 78.8 1.1 6.7e-12 45.8 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC72252.1 - 3e-15 56.4 2.2 1.1e-08 35.5 0.2 3.1 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC72252.1 - 1.2e-11 44.6 9.3 0.00047 20.4 0.4 5.0 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 PSC72252.1 - 5.3e-09 36.1 12.8 6e-05 23.3 0.7 4.4 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 PSC72252.1 - 1.3e-06 28.3 4.1 0.14 12.8 0.1 4.6 5 0 0 5 5 5 2 Ankyrin repeat Ser_hydrolase PF06821.13 PSC72252.1 - 0.01 15.7 1.1 0.018 14.9 1.1 1.4 1 0 0 1 1 1 0 Serine hydrolase CAS_CSE1 PF03378.15 PSC72253.1 - 1.4e-131 439.1 0.0 2.4e-131 438.3 0.0 1.4 1 0 0 1 1 1 1 CAS/CSE protein, C-terminus Cse1 PF08506.10 PSC72253.1 - 1.5e-115 386.0 0.0 2.4e-115 385.3 0.0 1.3 1 0 0 1 1 1 1 Cse1 IBN_N PF03810.19 PSC72253.1 - 2e-09 37.2 0.0 2.5e-08 33.7 0.0 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 PSC72253.1 - 0.00034 20.7 0.3 0.0088 16.1 0.0 3.2 3 1 0 3 3 3 1 Exportin 1-like protein MMS19_N PF14500.6 PSC72253.1 - 0.042 13.4 0.2 0.62 9.6 0.0 2.9 3 0 0 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II XPC-binding PF09280.11 PSC72253.1 - 1.9 8.3 0.0 1.9 8.3 0.0 3.5 4 0 0 4 4 4 0 XPC-binding domain Isy1 PF06246.12 PSC72254.1 - 2.1e-90 302.7 1.5 2.6e-90 302.5 1.5 1.1 1 0 0 1 1 1 1 Isy1-like splicing family DUF4837 PF16125.5 PSC72254.1 - 0.14 11.1 0.0 1.1 8.2 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4837) Proteasome PF00227.26 PSC72255.1 - 2.4e-57 193.5 0.5 3e-57 193.2 0.5 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 PSC72255.1 - 3.1e-14 52.3 0.1 6.6e-14 51.3 0.1 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ERG4_ERG24 PF01222.17 PSC72256.1 - 3.8e-138 460.9 3.3 4.7e-138 460.6 3.3 1.2 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 PSC72256.1 - 0.00046 19.8 0.1 0.00083 18.9 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DAGAT PF03982.13 PSC72257.1 - 4.5e-25 88.2 0.0 6.6e-25 87.6 0.0 1.2 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Proteasom_PSMB PF10508.9 PSC72258.1 - 9.3e-13 47.5 0.0 1.1e-07 30.7 0.0 2.2 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit HEAT_2 PF13646.6 PSC72258.1 - 0.0067 16.8 35.3 0.15 12.4 5.8 5.9 3 2 3 6 6 6 4 HEAT repeats Arm PF00514.23 PSC72258.1 - 0.07 13.2 2.8 18 5.5 0.1 3.8 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 PSC72258.1 - 2.4 8.6 21.4 18 5.9 0.2 7.6 8 0 0 8 8 8 0 HEAT repeat HAD_2 PF13419.6 PSC72259.1 - 9.9e-06 25.8 0.0 1.3e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PSC72259.1 - 0.00018 21.5 0.0 0.0003 20.8 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.26 PSC72259.1 - 0.038 14.3 0.0 0.046 14.0 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase G6PD_C PF02781.16 PSC72260.1 - 1.3e-115 385.6 0.0 1.7e-115 385.2 0.0 1.1 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 PSC72260.1 - 1.9e-56 191.5 0.0 3e-56 190.8 0.0 1.3 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Spt20 PF12090.8 PSC72261.1 - 0.0013 18.4 32.1 0.0018 17.9 32.1 1.1 1 0 0 1 1 1 1 Spt20 family DDHD PF02862.17 PSC72261.1 - 0.0085 16.3 2.6 0.014 15.6 2.6 1.3 1 0 0 1 1 1 1 DDHD domain TFIIA PF03153.13 PSC72261.1 - 0.13 12.2 36.2 0.23 11.4 36.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 PSC72261.1 - 0.22 10.4 28.8 0.34 9.8 28.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Plasmodium_Vir PF05795.11 PSC72261.1 - 1 8.7 6.2 1.5 8.2 6.2 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein Peptidase_C58 PF03543.14 PSC72261.1 - 1.7 8.3 15.5 2.7 7.6 15.5 1.2 1 0 0 1 1 1 0 Yersinia/Haemophilus virulence surface antigen EPL1 PF10513.9 PSC72261.1 - 2.5 8.5 12.7 4 7.8 12.7 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like FliP PF00813.20 PSC72261.1 - 3 7.7 4.8 4.6 7.1 4.8 1.2 1 0 0 1 1 1 0 FliP family AUX_IAA PF02309.16 PSC72261.1 - 3.8 7.3 8.5 5.7 6.7 8.5 1.2 1 0 0 1 1 1 0 AUX/IAA family Suf PF05843.14 PSC72261.1 - 3.8 7.4 17.3 6.2 6.7 17.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TERB2 PF15101.6 PSC72261.1 - 4.8 7.2 15.2 7.4 6.6 15.2 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 eIF-3_zeta PF05091.12 PSC72261.1 - 5.1 6.0 17.4 7 5.5 17.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Tim54 PF11711.8 PSC72261.1 - 5.6 5.7 12.5 8.2 5.1 12.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CPSF100_C PF13299.6 PSC72261.1 - 5.6 7.1 10.9 10 6.3 10.9 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal GREB1 PF15782.5 PSC72261.1 - 6.6 3.7 11.4 8.7 3.3 11.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF3408 PF11888.8 PSC72261.1 - 6.8 6.8 11.2 13 6.0 11.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) Presenilin PF01080.17 PSC72261.1 - 7.8 5.1 18.0 11 4.6 18.0 1.1 1 0 0 1 1 1 0 Presenilin NPR3 PF03666.13 PSC72261.1 - 7.8 5.2 11.4 11 4.7 11.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM60A PF15396.6 PSC72261.1 - 8.2 6.4 7.1 12 5.8 7.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A DUF4746 PF15928.5 PSC72261.1 - 8.6 5.7 8.9 13 5.1 8.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) U-box PF04564.15 PSC72262.1 - 2.9e-11 43.4 0.0 4.5e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 U-box domain Cellulase PF00150.18 PSC72263.1 - 2.1e-13 50.3 0.1 4.4e-13 49.3 0.1 1.5 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) EGF_CA PF07645.15 PSC72263.1 - 1.3e-07 31.7 6.9 1.3e-07 31.7 6.9 3.0 3 0 0 3 3 3 1 Calcium-binding EGF domain EGF_3 PF12947.7 PSC72263.1 - 2e-05 24.7 4.5 2e-05 24.7 4.5 2.0 2 0 0 2 2 2 1 EGF domain PAN_1 PF00024.26 PSC72263.1 - 0.01 15.8 1.7 0.023 14.7 1.7 1.5 1 0 0 1 1 1 0 PAN domain EGF PF00008.27 PSC72263.1 - 2 8.8 8.5 0.53 10.6 4.7 2.1 2 0 0 2 2 2 0 EGF-like domain Adaptin_N PF01602.20 PSC72264.1 - 4.2e-95 319.3 14.6 5.7e-95 318.8 14.6 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Coatamer_beta_C PF07718.12 PSC72264.1 - 2.1e-56 189.7 0.1 4.5e-56 188.6 0.1 1.6 1 0 0 1 1 1 1 Coatomer beta C-terminal region Coatomer_b_Cpla PF14806.6 PSC72264.1 - 5.1e-56 188.1 0.0 1.2e-55 186.9 0.0 1.7 1 0 0 1 1 1 1 Coatomer beta subunit appendage platform HEAT_2 PF13646.6 PSC72264.1 - 2.4e-08 34.3 16.6 2.8e-06 27.6 0.0 6.0 4 1 3 7 7 7 2 HEAT repeats Cnd1 PF12717.7 PSC72264.1 - 6.6e-08 32.8 10.2 3.2e-06 27.3 0.3 4.5 2 1 1 3 3 3 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PSC72264.1 - 0.00011 22.1 12.9 0.024 14.8 0.0 7.4 7 1 2 9 9 8 1 HEAT repeat Cohesin_HEAT PF12765.7 PSC72264.1 - 0.027 14.8 0.4 0.093 13.1 0.0 2.1 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Alpha_adaptinC2 PF02883.20 PSC72264.1 - 0.056 13.8 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 Adaptin C-terminal domain DNA_alkylation PF08713.11 PSC72264.1 - 0.071 12.8 0.0 1 9.1 0.1 2.5 1 1 1 2 2 2 0 DNA alkylation repair enzyme Phage_TAC_12 PF12363.8 PSC72264.1 - 0.095 13.1 1.0 1.2 9.6 0.1 2.6 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC HEAT_EZ PF13513.6 PSC72264.1 - 0.34 11.5 0.0 0.34 11.5 0.0 4.3 4 1 1 5 5 3 0 HEAT-like repeat Histone PF00125.24 PSC72265.1 - 2.9e-54 183.0 1.9 3.2e-54 182.8 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 PSC72265.1 - 0.00013 22.5 1.7 0.00016 22.2 1.7 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 PSC72265.1 - 0.00045 20.5 0.0 0.00069 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 PSC72265.1 - 0.00049 20.2 0.5 0.00074 19.6 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 PSC72265.1 - 0.0052 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PSC72265.1 - 0.016 15.3 0.1 0.031 14.3 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit FH2 PF02181.23 PSC72266.1 - 2.5e-41 142.1 0.0 4.8e-41 141.1 0.0 1.4 1 0 0 1 1 1 1 Formin Homology 2 Domain PH PF00169.29 PSC72266.1 - 3.9e-08 33.7 0.0 6.2e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 PH domain Drf_GBD PF06371.13 PSC72266.1 - 0.014 15.0 0.0 0.022 14.3 0.0 1.2 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain PH_6 PF15406.6 PSC72266.1 - 0.14 12.5 0.0 0.14 12.5 0.0 2.5 3 0 0 3 3 3 0 Pleckstrin homology domain Fis1_TPR_C PF14853.6 PSC72268.1 - 0.078 13.1 1.6 0.099 12.7 0.1 2.0 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 PSC72268.1 - 1.4 9.2 8.7 11 6.4 0.2 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_L44 PF00935.19 PSC72269.1 - 1.8e-36 124.4 11.4 2.8e-36 123.8 11.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L44 Ribosomal_L33 PF00471.20 PSC72269.1 - 3.5 8.2 12.6 3 8.3 2.0 2.6 2 0 0 2 2 2 0 Ribosomal protein L33 Cu_amine_oxid PF01179.20 PSC72271.1 - 5e-82 276.0 0.3 1.8e-44 152.3 0.4 2.1 1 1 1 2 2 2 2 Copper amine oxidase, enzyme domain Cu_amine_oxidN2 PF02727.16 PSC72271.1 - 4.6e-08 33.2 0.0 9.4e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Copper amine oxidase, N2 domain DUF1965 PF09248.10 PSC72271.1 - 2.9e-05 23.7 0.0 7.3e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1965) GATA PF00320.27 PSC72272.1 - 7.4e-09 35.1 11.5 1.4e-08 34.2 11.5 1.5 1 0 0 1 1 1 1 GATA zinc finger CBFD_NFYB_HMF PF00808.23 PSC72273.1 - 2.4e-27 95.0 0.0 4.2e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 PSC72273.1 - 0.00059 19.8 0.1 0.0012 18.8 0.0 1.5 2 0 0 2 2 2 1 Bromodomain associated Histone PF00125.24 PSC72273.1 - 0.00062 20.1 0.3 0.001 19.4 0.0 1.5 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 PSC72273.1 - 0.00098 19.2 0.0 0.0012 19.0 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Vps8 PF12816.7 PSC72273.1 - 0.052 13.0 0.0 0.17 11.4 0.0 1.7 1 1 1 2 2 2 0 Golgi CORVET complex core vacuolar protein 8 CENP-X PF09415.10 PSC72273.1 - 0.073 13.4 0.9 1.9 8.9 0.0 2.3 2 0 0 2 2 2 0 CENP-S associating Centromere protein X DUF4106 PF13388.6 PSC72274.1 - 0.54 9.4 3.2 0.66 9.1 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Cyclin_N2 PF16500.5 PSC72274.1 - 1.3 9.7 6.7 0.32 11.7 3.5 1.6 2 0 0 2 2 2 0 N-terminal region of cyclin_N DUF4106 PF13388.6 PSC72275.1 - 0.54 9.4 3.2 0.66 9.2 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Cyclin_N2 PF16500.5 PSC72275.1 - 1.4 9.7 6.7 0.32 11.7 3.5 1.6 2 0 0 2 2 2 0 N-terminal region of cyclin_N CENP-T_C PF15511.6 PSC72277.1 - 2e-08 34.3 0.1 2.5e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PSC72277.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 PSC72277.1 - 0.00022 21.3 0.1 0.00031 20.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 PSC72277.1 - 0.0011 18.9 0.1 0.0017 18.4 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 PSC72277.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PSC72277.1 - 0.0015 18.9 0.1 0.0017 18.8 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 PSC72277.1 - 0.033 14.3 0.0 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit PI3_PI4_kinase PF00454.27 PSC72278.1 - 8.4e-30 104.4 0.0 1.7e-19 70.7 0.0 2.2 1 1 1 2 2 2 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 PSC72278.1 - 3.4e-11 42.9 0.0 1.3e-10 40.9 0.0 1.8 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CENP-T_C PF15511.6 PSC72279.1 - 2e-08 34.3 0.1 2.5e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PSC72279.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 PSC72279.1 - 0.00022 21.3 0.1 0.00031 20.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 PSC72279.1 - 0.0011 18.9 0.1 0.0017 18.4 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 PSC72279.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PSC72279.1 - 0.0015 18.9 0.1 0.0017 18.8 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 PSC72279.1 - 0.033 14.3 0.0 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Arf PF00025.21 PSC72280.1 - 2.4e-58 196.5 0.0 2.9e-58 196.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 PSC72280.1 - 1.9e-14 53.9 0.0 2.5e-14 53.5 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PSC72280.1 - 1e-13 51.2 0.0 1.1e-13 51.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 PSC72280.1 - 6.8e-09 35.4 0.0 8.4e-09 35.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 PSC72280.1 - 2.9e-06 26.7 0.0 0.0011 18.2 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 PSC72280.1 - 1e-05 25.6 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PSC72280.1 - 0.00056 19.3 0.0 0.00066 19.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 PSC72280.1 - 0.011 15.3 0.1 0.019 14.5 0.1 1.6 1 1 0 1 1 1 0 Ferrous iron transport protein B 6PF2K PF01591.18 PSC72280.1 - 0.11 11.8 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 6-phosphofructo-2-kinase ZT_dimer PF16916.5 PSC72281.1 - 1.9e-11 43.9 1.1 1.9e-11 43.9 1.1 1.5 2 0 0 2 2 2 1 Dimerisation domain of Zinc Transporter Cation_efflux PF01545.21 PSC72281.1 - 1.1e-05 25.2 1.0 1.4e-05 24.9 1.0 1.1 1 0 0 1 1 1 1 Cation efflux family Rab5ip PF07019.12 PSC72284.1 - 1.3e-08 35.3 2.9 1.6e-08 35.0 2.9 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) WD40 PF00400.32 PSC72285.1 - 3.1e-25 88.0 10.7 2.7e-07 31.2 0.2 7.2 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC72285.1 - 4.2e-11 43.0 0.0 0.00088 19.5 0.0 4.9 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PSC72285.1 - 0.26 10.2 0.0 21 4.0 0.0 2.5 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 PSC72285.1 - 0.32 11.0 1.2 8.3 6.5 0.4 3.2 3 1 0 3 3 3 0 WD40-like Beta Propeller Repeat Asn_synthase PF00733.21 PSC72286.1 - 1.9e-84 284.4 0.3 5.4e-52 177.6 0.1 2.2 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 PSC72286.1 - 5.4e-28 97.4 0.0 9.1e-28 96.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 PSC72286.1 - 3.2e-20 72.7 0.0 5.4e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain zf-HC5HC2H_2 PF13832.6 PSC72286.1 - 1.8e-16 60.3 13.6 6e-15 55.4 6.8 3.1 2 1 0 2 2 2 2 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 PSC72286.1 - 3.1e-16 59.4 2.2 3.1e-16 59.4 2.2 3.1 2 1 1 3 3 2 2 PHD-like zinc-binding domain DUF3700 PF12481.8 PSC72286.1 - 1.8e-10 40.7 0.0 3.3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein PHD_2 PF13831.6 PSC72286.1 - 2e-09 36.9 4.4 2e-09 36.9 4.4 2.5 3 0 0 3 3 3 1 PHD-finger PHD PF00628.29 PSC72286.1 - 2.9e-07 30.3 4.2 2.9e-07 30.3 4.2 3.1 3 0 0 3 3 3 2 PHD-finger NAD_synthase PF02540.17 PSC72286.1 - 0.098 11.8 0.0 0.24 10.5 0.0 1.6 2 0 0 2 2 2 0 NAD synthase tRNA_Me_trans PF03054.16 PSC72286.1 - 0.2 10.4 0.0 0.32 9.7 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase zf-UDP PF14569.6 PSC72286.1 - 0.25 11.5 6.5 0.73 10.0 6.5 1.8 1 0 0 1 1 1 0 Zinc-binding RING-finger Ribosomal_S9 PF00380.19 PSC72287.1 - 1.3e-31 109.6 0.3 1.5e-31 109.4 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Xpo1 PF08389.12 PSC72289.1 - 4.2e-12 46.4 0.0 5.2e-11 42.8 0.0 2.7 3 0 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 PSC72289.1 - 4.9e-08 32.8 0.2 1.2e-07 31.6 0.2 1.7 1 0 0 1 1 1 1 Importin-beta N-terminal domain Importin_rep PF18773.1 PSC72289.1 - 0.00022 20.9 0.0 0.00051 19.7 0.0 1.6 1 0 0 1 1 1 1 Importin 13 repeat Importin_rep_3 PF18806.1 PSC72289.1 - 0.032 14.3 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 Importin 13 repeat Mobilization_B PF17511.2 PSC72289.1 - 3.9 7.9 7.9 1.5 9.1 0.5 2.9 2 0 0 2 2 2 0 Mobilization protein B MPLKIP PF15502.6 PSC72290.1 - 2.1e-10 40.6 0.4 1.1e-09 38.4 0.0 2.4 2 1 0 2 2 2 1 M-phase-specific PLK1-interacting protein Vps55 PF04133.14 PSC72291.1 - 4.6e-18 65.3 0.5 5e-18 65.2 0.5 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 Yippee-Mis18 PF03226.14 PSC72292.1 - 1.3e-17 63.9 0.7 1.4e-17 63.8 0.7 1.0 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly ATP-synt_ab PF00006.25 PSC72293.1 - 4.2e-68 229.2 0.0 6.1e-68 228.6 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 PSC72293.1 - 7.8e-12 45.5 2.1 1.4e-11 44.8 2.1 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Peptidase_M50 PF02163.22 PSC72294.1 - 0.0077 15.5 0.5 0.02 14.1 0.0 1.9 2 0 0 2 2 2 1 Peptidase family M50 AAA_2 PF07724.14 PSC72295.1 - 3.6e-54 183.4 0.0 5.6e-52 176.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 PSC72295.1 - 1.4e-27 95.7 0.6 3.2e-27 94.5 0.6 1.6 1 0 0 1 1 1 1 AAA lid domain AAA PF00004.29 PSC72295.1 - 3.2e-20 72.9 0.0 5.5e-10 39.8 0.0 2.8 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Clp_N PF02861.20 PSC72295.1 - 1.2e-19 70.2 0.4 2.1e-08 34.2 0.0 2.8 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component ClpB_D2-small PF10431.9 PSC72295.1 - 4.1e-19 68.4 0.5 9.7e-19 67.2 0.5 1.7 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 PSC72295.1 - 1.3e-18 67.4 0.0 4.8e-12 46.1 0.0 3.0 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PSC72295.1 - 3.2e-09 37.4 4.1 0.00025 21.5 0.5 4.5 2 1 1 3 3 3 2 AAA ATPase domain Sigma54_activat PF00158.26 PSC72295.1 - 4.3e-07 29.8 0.0 0.00013 21.7 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_22 PF13401.6 PSC72295.1 - 5.9e-07 29.8 1.8 0.038 14.2 0.2 4.3 2 2 0 2 2 2 2 AAA domain AAA_18 PF13238.6 PSC72295.1 - 1.4e-05 25.6 0.2 0.17 12.4 0.0 3.3 3 0 0 3 3 2 2 AAA domain IstB_IS21 PF01695.17 PSC72295.1 - 3.6e-05 23.6 0.0 0.057 13.1 0.0 3.1 3 0 0 3 3 3 1 IstB-like ATP binding protein RuvB_N PF05496.12 PSC72295.1 - 4.9e-05 23.1 0.3 1.5 8.5 0.0 4.0 4 0 0 4 4 4 2 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 PSC72295.1 - 7.8e-05 22.6 0.1 0.034 14.1 0.0 2.8 2 0 0 2 2 2 1 NACHT domain Zeta_toxin PF06414.12 PSC72295.1 - 8.6e-05 21.9 0.1 0.015 14.6 0.0 2.7 2 0 0 2 2 2 1 Zeta toxin TniB PF05621.11 PSC72295.1 - 8.8e-05 22.0 0.0 0.53 9.7 0.0 3.6 3 0 0 3 3 3 1 Bacterial TniB protein RNA_helicase PF00910.22 PSC72295.1 - 9.9e-05 22.7 0.5 0.94 9.9 0.0 3.3 4 0 0 4 4 3 2 RNA helicase AAA_3 PF07726.11 PSC72295.1 - 0.00016 21.5 0.0 0.46 10.3 0.0 3.5 4 0 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 PSC72295.1 - 0.00032 20.7 0.0 0.98 9.4 0.0 2.9 3 0 0 3 3 3 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 PSC72295.1 - 0.00053 20.2 2.9 1.7 8.8 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_7 PF12775.7 PSC72295.1 - 0.00065 19.3 0.0 0.28 10.7 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 PSC72295.1 - 0.0012 18.2 0.3 5.6 6.3 0.0 3.3 2 1 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 PSC72295.1 - 0.0013 18.8 0.0 0.22 11.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain Roc PF08477.13 PSC72295.1 - 0.0037 17.5 0.0 2 8.7 0.0 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase NTPase_1 PF03266.15 PSC72295.1 - 0.0066 16.4 0.1 1.9 8.4 0.0 3.0 3 0 0 3 3 3 1 NTPase AAA_28 PF13521.6 PSC72295.1 - 0.0069 16.6 0.1 1.2 9.4 0.0 3.2 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 PSC72295.1 - 0.0076 15.8 0.0 0.9 9.1 0.0 2.9 2 0 0 2 2 2 1 AAA domain DNA_pol3_delta2 PF13177.6 PSC72295.1 - 0.0091 15.8 0.0 7.3 6.3 0.0 3.2 3 0 0 3 3 3 0 DNA polymerase III, delta subunit RsgA_GTPase PF03193.16 PSC72295.1 - 0.019 14.9 0.0 3 7.7 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_24 PF13479.6 PSC72295.1 - 0.036 13.8 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 PSC72295.1 - 0.055 14.0 0.0 3 8.3 0.0 2.5 2 0 0 2 2 2 0 ABC transporter ATPase_2 PF01637.18 PSC72295.1 - 0.063 13.2 0.1 34 4.2 0.1 3.5 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea ResIII PF04851.15 PSC72295.1 - 0.065 13.2 0.0 2 8.4 0.0 2.9 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit UVR PF02151.19 PSC72295.1 - 0.13 12.0 2.1 0.44 10.3 2.1 2.0 1 0 0 1 1 1 0 UvrB/uvrC motif NIF PF03031.18 PSC72296.1 - 1.2e-22 80.4 0.0 1.8e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 PSC72296.1 - 0.00039 20.7 0.0 0.0011 19.3 0.1 1.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 PSC72296.1 - 0.0024 17.8 0.1 0.0046 16.9 0.1 1.4 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 PSC72296.1 - 0.022 15.1 0.5 0.044 14.1 0.5 1.4 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain zf-HIT PF04438.16 PSC72297.1 - 1.1e-10 41.1 12.1 1.8e-10 40.5 12.1 1.3 1 0 0 1 1 1 1 HIT zinc finger SHQ1 PF04925.15 PSC72297.1 - 0.00011 21.8 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 SHQ1 protein YL1_C PF08265.11 PSC72297.1 - 0.01 15.6 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain zf-MYND PF01753.18 PSC72297.1 - 0.54 10.4 15.6 1.1 9.3 15.6 1.6 1 0 0 1 1 1 0 MYND finger zf-HIT PF04438.16 PSC72298.1 - 1.2e-10 41.1 12.1 1.8e-10 40.5 12.1 1.3 1 0 0 1 1 1 1 HIT zinc finger SHQ1 PF04925.15 PSC72298.1 - 0.00011 21.8 0.0 0.00018 21.2 0.0 1.2 1 0 0 1 1 1 1 SHQ1 protein YL1_C PF08265.11 PSC72298.1 - 0.01 15.6 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain zf-MYND PF01753.18 PSC72298.1 - 0.55 10.4 15.6 1.2 9.3 15.6 1.5 1 0 0 1 1 1 0 MYND finger NGP1NT PF08153.12 PSC72299.1 - 6.9e-47 158.9 0.2 1.1e-46 158.2 0.2 1.4 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 PSC72299.1 - 3.2e-16 59.4 0.1 1.9e-13 50.5 0.0 2.4 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 PSC72299.1 - 6.4e-07 29.0 0.1 1.1e-05 25.1 0.1 2.1 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 PSC72299.1 - 0.00023 21.1 0.0 0.00045 20.2 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 PSC72299.1 - 0.0068 16.5 0.4 0.92 9.5 0.1 2.9 2 1 1 3 3 3 1 Dynamin family Arf PF00025.21 PSC72299.1 - 0.011 15.2 0.1 5.5 6.4 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family Roc PF08477.13 PSC72299.1 - 0.098 12.9 0.0 18 5.5 0.0 2.5 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 PSC72299.1 - 0.12 11.9 0.0 3.6 7.1 0.0 2.6 1 1 0 3 3 3 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 PSC72299.1 - 0.25 11.7 1.0 1.1 9.6 0.0 2.5 3 0 0 3 3 3 0 AAA ATPase domain Hydrolase_6 PF13344.6 PSC72300.1 - 2.6e-24 85.2 0.0 7.8e-24 83.7 0.0 1.8 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase PAC4 PF16093.5 PSC72300.1 - 1.3e-16 60.5 0.2 4e-16 59.0 0.0 2.0 2 0 0 2 2 2 1 Proteasome assembly chaperone 4 Hydrolase_like PF13242.6 PSC72300.1 - 2.1e-08 34.1 0.0 3.8e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like PGP_phosphatase PF09419.10 PSC72300.1 - 0.005 16.5 0.0 0.09 12.4 0.0 2.4 2 0 0 2 2 2 1 Mitochondrial PGP phosphatase Hydrolase PF00702.26 PSC72300.1 - 0.017 15.4 0.0 1.7 8.9 0.0 2.6 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase OSCP PF00213.18 PSC72301.1 - 9.2e-44 149.6 0.6 2.6e-43 148.1 0.0 2.0 2 1 0 2 2 2 1 ATP synthase delta (OSCP) subunit DUF842 PF05811.13 PSC72301.1 - 1.2e-33 115.6 18.8 2e-33 114.9 18.8 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF842) DUF790 PF05626.11 PSC72301.1 - 0.021 13.6 0.1 0.032 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF790) Apolipoprotein PF01442.18 PSC72301.1 - 0.66 9.8 11.6 0.46 10.3 6.4 3.1 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain DUF4355 PF14265.6 PSC72301.1 - 1.1 9.5 4.3 0.44 10.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4355) MatE PF01554.18 PSC72302.1 - 5e-25 88.0 27.1 9.6e-16 57.8 6.5 2.8 2 1 1 3 3 3 2 MatE DnaJ PF00226.31 PSC72303.1 - 1.4e-23 82.7 0.1 3.1e-23 81.7 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain NCD1 PF04904.13 PSC72303.1 - 0.057 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) SAM_2 PF07647.17 PSC72305.1 - 5.2e-06 26.5 0.0 1.1e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PSC72305.1 - 0.00011 22.6 0.0 0.00021 21.7 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF1990 PF09348.10 PSC72305.1 - 0.25 11.4 3.3 0.15 12.1 0.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1990) DUF5082 PF16888.5 PSC72305.1 - 0.73 10.1 5.2 3.3 8.0 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5082) TFIIA PF03153.13 PSC72305.1 - 3 7.7 10.7 3.6 7.5 10.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ATG16 PF08614.11 PSC72305.1 - 3.1 8.0 15.7 8.7 6.5 15.0 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) FadA PF09403.10 PSC72305.1 - 6.4 7.3 10.1 2.4 8.7 2.4 2.3 2 0 0 2 2 2 0 Adhesion protein FadA ABC_tran_CTD PF16326.5 PSC72305.1 - 7.8 6.8 10.4 10 6.5 1.1 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain CDC14 PF08045.11 PSC72307.1 - 0.062 12.4 0.0 1.4 8.0 0.0 2.0 2 0 0 2 2 2 0 Cell division control protein 14, SIN component SAM_2 PF07647.17 PSC72308.1 - 5.2e-07 29.7 0.0 6.3e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PSC72308.1 - 1.1e-05 25.8 0.0 1.3e-05 25.5 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF2839 PF10999.8 PSC72309.1 - 0.00015 22.1 0.1 0.00031 21.0 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2839) AIP3 PF03915.13 PSC72309.1 - 0.13 11.3 0.8 0.16 11.1 0.8 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 CENP-T_C PF15511.6 PSC72310.1 - 2e-08 34.3 0.1 2.5e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PSC72310.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 PSC72310.1 - 0.00022 21.3 0.1 0.00031 20.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 PSC72310.1 - 0.0011 18.9 0.1 0.0017 18.4 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 PSC72310.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PSC72310.1 - 0.0015 18.9 0.1 0.0017 18.8 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 PSC72310.1 - 0.033 14.3 0.0 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit DUF1917 PF08939.10 PSC72311.1 - 1.1e-07 32.0 0.0 1.8e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1917) SUI1 PF01253.22 PSC72312.1 - 1e-18 67.6 0.4 1.6e-18 67.0 0.4 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 TctA PF01970.16 PSC72312.1 - 0.17 10.6 0.4 0.2 10.3 0.4 1.0 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family MULE PF10551.9 PSC72313.1 - 4.7e-10 39.7 0.0 9.8e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 MULE transposase domain Ribosomal_S21 PF01165.20 PSC72314.1 - 6.7e-13 48.1 2.9 1.4e-12 47.2 2.9 1.6 1 0 0 1 1 1 1 Ribosomal protein S21 Histone PF00125.24 PSC72315.1 - 9.9e-16 58.3 0.1 1.3e-15 57.9 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC72315.1 - 0.0077 16.5 0.1 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DnaJ PF00226.31 PSC72315.1 - 0.06 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain RP-C PF03428.13 PSC72315.1 - 0.06 13.0 0.4 3.4 7.3 0.0 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain TFIID_20kDa PF03847.13 PSC72315.1 - 0.2 12.2 0.0 0.33 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Histone PF00125.24 PSC72316.1 - 1e-15 58.3 0.0 1.3e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC72316.1 - 0.008 16.4 0.1 0.016 15.5 0.1 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DnaJ PF00226.31 PSC72316.1 - 0.058 13.5 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 DnaJ domain RP-C PF03428.13 PSC72316.1 - 0.072 12.7 0.4 3.8 7.1 0.0 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain TFIID_20kDa PF03847.13 PSC72316.1 - 0.2 12.2 0.0 0.33 11.5 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A DNA_pol_B PF00136.21 PSC72317.1 - 1e-87 294.8 0.0 1.4e-87 294.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 PSC72317.1 - 1.4e-13 50.7 0.0 3.8e-06 26.3 0.0 2.4 2 0 0 2 2 2 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 PSC72317.1 - 6.5e-11 42.5 0.5 6.5e-11 42.5 0.5 2.3 2 0 0 2 2 2 1 C4-type zinc-finger of DNA polymerase delta Coa1 PF08695.10 PSC72318.1 - 0.00012 21.7 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 Cytochrome oxidase complex assembly protein 1 TIM21 PF08294.11 PSC72318.1 - 0.17 11.8 0.0 0.45 10.4 0.0 1.6 1 0 0 1 1 1 0 TIM21 COG4 PF08318.12 PSC72319.1 - 3e-55 187.6 0.0 4.9e-55 186.9 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.13 PSC72319.1 - 0.00023 20.2 0.0 0.00041 19.4 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Sec10 PF07393.11 PSC72319.1 - 0.012 14.0 0.0 0.12 10.8 0.1 2.1 2 0 0 2 2 2 0 Exocyst complex component Sec10 Nsp1_C PF05064.13 PSC72319.1 - 0.042 13.6 0.5 0.16 11.8 0.5 2.0 1 0 0 1 1 1 0 Nsp1-like C-terminal region Pox_F11 PF04943.12 PSC72319.1 - 0.044 12.9 0.1 0.088 11.9 0.1 1.4 1 0 0 1 1 1 0 Poxvirus F11 protein Vps53_N PF04100.12 PSC72319.1 - 0.08 11.9 0.6 0.17 10.9 0.6 1.5 1 0 0 1 1 1 0 Vps53-like, N-terminal Cluap1 PF10234.9 PSC72319.1 - 0.11 11.9 0.8 0.23 10.9 0.8 1.5 1 0 0 1 1 1 0 Clusterin-associated protein-1 Sec6 PF06046.13 PSC72319.1 - 0.13 10.6 0.0 0.23 9.8 0.0 1.5 1 0 0 1 1 1 0 Exocyst complex component Sec6 HSCB_C PF07743.13 PSC72319.1 - 0.52 10.8 7.0 10 6.7 1.0 4.2 4 1 0 4 4 4 0 HSCB C-terminal oligomerisation domain COG4 PF08318.12 PSC72320.1 - 6.3e-55 186.6 0.0 1e-54 185.9 0.0 1.3 1 0 0 1 1 1 1 COG4 transport protein RINT1_TIP1 PF04437.13 PSC72320.1 - 0.00022 20.3 0.0 0.00041 19.4 0.0 1.3 1 0 0 1 1 1 1 RINT-1 / TIP-1 family Sec10 PF07393.11 PSC72320.1 - 0.0063 15.0 0.0 0.11 10.8 0.1 2.2 2 0 0 2 2 2 1 Exocyst complex component Sec10 Nsp1_C PF05064.13 PSC72320.1 - 0.04 13.7 0.5 0.16 11.8 0.5 2.0 1 0 0 1 1 1 0 Nsp1-like C-terminal region Pox_F11 PF04943.12 PSC72320.1 - 0.044 12.9 0.1 0.088 11.9 0.1 1.4 1 0 0 1 1 1 0 Poxvirus F11 protein Vps53_N PF04100.12 PSC72320.1 - 0.079 11.9 0.6 0.17 10.9 0.6 1.5 1 0 0 1 1 1 0 Vps53-like, N-terminal Cluap1 PF10234.9 PSC72320.1 - 0.11 11.9 0.8 0.23 10.9 0.8 1.5 1 0 0 1 1 1 0 Clusterin-associated protein-1 Sec6 PF06046.13 PSC72320.1 - 0.14 10.5 0.0 0.23 9.8 0.0 1.4 1 0 0 1 1 1 0 Exocyst complex component Sec6 HSCB_C PF07743.13 PSC72320.1 - 0.6 10.6 7.6 10 6.7 1.0 4.2 4 1 0 4 4 4 0 HSCB C-terminal oligomerisation domain Methyltransf_31 PF13847.6 PSC72321.1 - 3.4e-19 69.1 0.0 6e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC72321.1 - 3.2e-17 62.9 0.0 7.7e-17 61.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC72321.1 - 4e-17 62.7 0.0 1e-16 61.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC72321.1 - 1.6e-16 60.4 0.0 2.6e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 PSC72321.1 - 4.5e-09 37.0 0.0 8.8e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Cation_efflux PF01545.21 PSC72321.1 - 5.4e-06 26.3 4.2 7.6e-06 25.8 4.2 1.2 1 0 0 1 1 1 1 Cation efflux family DUF938 PF06080.12 PSC72321.1 - 0.0027 17.5 0.0 0.0047 16.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_23 PF13489.6 PSC72321.1 - 0.0041 17.0 0.0 0.0073 16.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltr_RsmB-F PF01189.17 PSC72321.1 - 0.0048 16.6 0.0 0.008 15.8 0.0 1.3 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F PCMT PF01135.19 PSC72321.1 - 0.008 15.9 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 PSC72321.1 - 0.025 14.2 0.0 0.064 12.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_8 PF05148.15 PSC72321.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 Hypothetical methyltransferase DUF2358 PF10184.9 PSC72322.1 - 3.7e-27 94.8 0.0 4.6e-27 94.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 PSC72322.1 - 7.7e-05 23.3 0.0 0.00011 22.8 0.0 1.3 1 0 0 1 1 1 1 SnoaL-like domain MMU163 PF17119.5 PSC72322.1 - 0.035 13.3 0.0 4.4 6.4 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis TPR_1 PF00515.28 PSC72323.1 - 5.4e-46 152.6 12.5 2.4e-08 33.5 0.0 9.6 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_8 PF13181.6 PSC72323.1 - 2.2e-28 96.1 6.8 0.00036 20.5 0.0 8.1 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_2 PF07719.17 PSC72323.1 - 6.5e-28 94.6 48.7 4.7e-05 23.2 0.2 11.5 12 0 0 12 12 10 6 Tetratricopeptide repeat TPR_11 PF13414.6 PSC72323.1 - 1.3e-27 95.2 2.2 3.1e-08 33.2 0.0 7.6 4 2 4 8 8 8 5 TPR repeat ANAPC3 PF12895.7 PSC72323.1 - 3.3e-24 84.9 25.5 1.9e-14 53.6 5.6 5.5 3 1 2 5 5 5 4 Anaphase-promoting complex, cyclosome, subunit 3 Surp PF01805.20 PSC72323.1 - 2e-19 69.3 0.2 5.6e-19 67.9 0.2 1.8 1 0 0 1 1 1 1 Surp module TPR_12 PF13424.6 PSC72323.1 - 2.8e-15 56.3 42.3 0.00058 20.1 0.2 8.6 7 2 2 9 9 8 6 Tetratricopeptide repeat TPR_17 PF13431.6 PSC72323.1 - 2.3e-14 52.6 10.3 0.0003 21.0 0.1 8.5 8 0 0 8 8 8 1 Tetratricopeptide repeat RRM_1 PF00076.22 PSC72323.1 - 1.6e-12 47.1 0.0 3.4e-12 46.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TPR_7 PF13176.6 PSC72323.1 - 1.9e-11 43.1 5.7 0.057 13.5 0.2 7.2 5 1 1 6 6 6 3 Tetratricopeptide repeat TPR_16 PF13432.6 PSC72323.1 - 4.5e-10 40.0 9.7 8.8e-06 26.3 0.0 12.4 12 2 1 14 14 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 PSC72323.1 - 7.6e-10 39.2 38.8 0.00028 21.4 0.5 9.4 5 2 6 11 11 9 4 Tetratricopeptide repeat cwf21 PF08312.12 PSC72323.1 - 8.6e-10 38.6 1.4 9.7e-08 32.0 4.4 2.7 2 1 0 2 2 2 1 cwf21 domain TPR_14 PF13428.6 PSC72323.1 - 3.4e-07 30.5 62.4 0.078 13.8 0.0 13.3 7 2 7 14 14 10 7 Tetratricopeptide repeat TPR_10 PF13374.6 PSC72323.1 - 3.7e-06 26.6 12.1 1.2 9.1 0.2 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 PSC72323.1 - 9.4e-06 25.7 28.1 0.011 15.8 0.0 7.0 4 1 4 8 8 7 2 Tetratricopeptide repeat RRM_7 PF16367.5 PSC72323.1 - 0.00057 19.9 0.0 0.0013 18.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif TPR_15 PF13429.6 PSC72323.1 - 0.00067 18.9 23.4 0.037 13.3 0.2 5.1 3 1 2 5 5 4 3 Tetratricopeptide repeat CTD_bind PF04818.13 PSC72323.1 - 0.003 18.3 0.0 0.0071 17.1 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. TPR_20 PF14561.6 PSC72323.1 - 0.0051 17.1 1.0 0.0051 17.1 1.0 4.3 4 0 0 4 4 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 PSC72323.1 - 0.008 16.8 37.4 0.012 16.2 0.0 10.3 13 0 0 13 13 8 2 Tetratricopeptide repeat Phage_B PF02304.15 PSC72323.1 - 0.031 14.6 0.2 0.13 12.7 0.2 2.0 1 0 0 1 1 1 0 Scaffold protein B Fis1_TPR_C PF14853.6 PSC72323.1 - 0.031 14.3 1.4 30 4.8 0.1 4.0 4 0 0 4 4 3 0 Fis1 C-terminal tetratricopeptide repeat TFIIA PF03153.13 PSC72323.1 - 2.9 7.8 6.0 5.9 6.8 6.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PfkB PF00294.24 PSC72324.1 - 7.3e-12 45.2 0.7 1.1e-11 44.5 0.7 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase ABC_tran PF00005.27 PSC72325.1 - 1.4e-48 164.9 0.0 2.5e-24 86.3 0.0 3.4 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 PSC72325.1 - 9.7e-16 58.4 0.1 0.00073 19.4 0.0 4.2 3 1 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PSC72325.1 - 3.3e-14 52.8 0.2 0.00031 20.2 0.0 4.2 2 2 0 3 3 3 3 RecF/RecN/SMC N terminal domain HEAT PF02985.22 PSC72325.1 - 7.1e-11 41.4 3.7 0.087 13.1 0.0 5.1 4 0 0 4 4 4 3 HEAT repeat HEAT_2 PF13646.6 PSC72325.1 - 2.5e-09 37.4 2.0 0.0001 22.6 1.9 3.7 2 1 2 4 4 4 3 HEAT repeats 4HB PF17947.1 PSC72325.1 - 3.5e-09 36.6 0.1 1e-08 35.1 0.1 1.8 1 0 0 1 1 1 1 Four helical bundle domain AAA_29 PF13555.6 PSC72325.1 - 4.2e-08 32.8 0.3 0.0041 16.8 0.0 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain HEAT_EZ PF13513.6 PSC72325.1 - 6.6e-08 32.9 7.4 0.00037 20.9 0.0 4.9 5 0 0 5 5 3 2 HEAT-like repeat AAA_23 PF13476.6 PSC72325.1 - 1.1e-07 32.6 3.8 0.00081 19.9 0.0 3.1 3 1 1 4 4 4 2 AAA domain AAA_18 PF13238.6 PSC72325.1 - 1.7e-07 31.8 0.4 0.0077 16.8 0.1 3.4 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.6 PSC72325.1 - 3.8e-06 27.2 0.0 0.21 11.9 0.0 3.6 4 0 0 4 4 3 2 AAA domain AAA_16 PF13191.6 PSC72325.1 - 4e-06 27.3 0.0 0.071 13.5 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 PSC72325.1 - 4.6e-06 26.5 2.6 0.89 9.2 0.0 4.3 3 2 0 3 3 3 2 AAA domain AAA_28 PF13521.6 PSC72325.1 - 6.7e-06 26.4 0.0 0.52 10.5 0.0 3.4 3 0 0 3 3 3 2 AAA domain MeaB PF03308.16 PSC72325.1 - 8.4e-06 24.9 0.1 0.019 14.0 0.0 2.6 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 PSC72325.1 - 9.4e-06 25.6 0.0 0.031 14.2 0.0 2.6 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 PSC72325.1 - 1.3e-05 25.3 0.0 0.04 14.0 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.29 PSC72325.1 - 2.8e-05 24.6 0.0 0.45 10.9 0.0 3.4 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Vac14_Fab1_bd PF12755.7 PSC72325.1 - 3.3e-05 24.4 0.0 0.27 11.8 0.0 3.6 2 1 1 3 3 3 1 Vacuolar 14 Fab1-binding region RNA_helicase PF00910.22 PSC72325.1 - 7.3e-05 23.1 0.0 0.65 10.4 0.0 2.8 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.6 PSC72325.1 - 7.6e-05 22.9 0.0 0.52 10.5 0.0 2.8 2 0 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 PSC72325.1 - 0.00017 21.8 0.0 0.11 12.8 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_27 PF13514.6 PSC72325.1 - 0.00068 19.3 0.0 0.38 10.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.6 PSC72325.1 - 0.00077 19.3 0.0 0.23 11.1 0.0 2.8 3 0 0 3 3 2 1 AAA ATPase domain AAA_13 PF13166.6 PSC72325.1 - 0.0011 17.7 0.3 0.14 10.8 0.0 2.6 3 0 0 3 3 2 1 AAA domain NACHT PF05729.12 PSC72325.1 - 0.0016 18.4 0.0 0.54 10.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 PSC72325.1 - 0.0016 18.2 0.0 0.89 9.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain CLP1_P PF16575.5 PSC72325.1 - 0.0017 18.2 0.1 0.21 11.3 0.0 2.7 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Adaptin_N PF01602.20 PSC72325.1 - 0.0019 16.9 0.0 0.0041 15.8 0.0 1.5 1 1 0 1 1 1 1 Adaptin N terminal region ATPase_2 PF01637.18 PSC72325.1 - 0.0022 17.9 0.1 1.9 8.4 0.0 2.8 2 1 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_7 PF12775.7 PSC72325.1 - 0.0029 17.1 0.0 2.9 7.4 0.0 2.3 2 0 0 2 2 2 2 P-loop containing dynein motor region CLASP_N PF12348.8 PSC72325.1 - 0.0031 17.1 0.4 0.12 11.9 0.1 2.3 2 0 0 2 2 2 1 CLASP N terminal Cytidylate_kin PF02224.18 PSC72325.1 - 0.004 16.9 0.0 3.2 7.4 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase Chromo PF00385.24 PSC72325.1 - 0.0042 17.0 0.1 0.012 15.5 0.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Proteasom_PSMB PF10508.9 PSC72325.1 - 0.0045 15.6 0.0 0.0089 14.6 0.0 1.4 1 0 0 1 1 1 1 Proteasome non-ATPase 26S subunit DUF815 PF05673.13 PSC72325.1 - 0.0045 16.2 0.0 1.8 7.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 PSC72325.1 - 0.0079 16.2 0.0 3.2 7.8 0.0 2.9 2 1 0 2 2 2 1 AAA domain Adeno_IVa2 PF02456.15 PSC72325.1 - 0.011 14.6 0.0 3.7 6.2 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein Cnd1 PF12717.7 PSC72325.1 - 0.015 15.3 0.3 3.3 7.7 0.0 2.9 1 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 DUF87 PF01935.17 PSC72325.1 - 0.016 15.3 7.3 0.16 12.0 0.0 3.6 4 0 0 4 4 3 0 Helicase HerA, central domain cobW PF02492.19 PSC72325.1 - 0.017 14.7 0.8 4.5 6.8 0.0 3.0 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain Tti2 PF10521.9 PSC72325.1 - 0.019 14.5 0.0 5.3 6.5 0.0 2.4 2 0 0 2 2 2 0 Tti2 family ATP_bind_1 PF03029.17 PSC72325.1 - 0.025 14.3 0.3 10 5.8 0.0 2.9 3 0 0 3 3 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 PSC72325.1 - 0.032 14.1 0.1 8.4 6.3 0.1 2.8 2 0 0 2 2 2 0 NTPase AAA_5 PF07728.14 PSC72325.1 - 0.033 14.2 0.4 21 5.1 0.0 3.7 4 1 0 4 4 3 0 AAA domain (dynein-related subfamily) Rad17 PF03215.15 PSC72325.1 - 0.035 14.0 0.0 6.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain Zeta_toxin PF06414.12 PSC72325.1 - 0.072 12.4 0.6 6.3 6.0 0.0 3.1 3 0 0 3 3 3 0 Zeta toxin Cohesin_HEAT PF12765.7 PSC72325.1 - 0.096 13.0 2.3 3 8.2 0.1 2.8 2 0 0 2 2 2 0 HEAT repeat associated with sister chromatid cohesion Dynamin_N PF00350.23 PSC72325.1 - 0.12 12.5 0.0 4.2 7.4 0.0 2.8 2 0 0 2 2 2 0 Dynamin family TsaE PF02367.17 PSC72325.1 - 0.12 12.4 0.1 19 5.3 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF5499 PF17603.2 PSC72325.1 - 0.12 13.0 1.3 0.36 11.5 1.3 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5499) Roc PF08477.13 PSC72325.1 - 0.13 12.5 0.1 16 5.7 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Ank_2 PF12796.7 PSC72326.1 - 4.4e-42 142.6 0.9 6.4e-09 36.3 0.2 9.6 4 4 5 9 9 9 9 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC72326.1 - 3.8e-34 116.6 12.0 9.4e-05 22.9 0.2 12.9 10 5 4 14 14 14 11 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC72326.1 - 2.4e-28 97.8 28.5 3.3e-07 30.5 0.1 12.5 9 3 5 14 14 14 9 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC72326.1 - 3.5e-23 79.2 21.5 0.0031 17.9 0.0 14.7 18 0 0 18 18 18 6 Ankyrin repeat Ank PF00023.30 PSC72326.1 - 1.9e-17 62.8 41.4 0.014 15.8 0.2 14.7 16 0 0 16 16 16 7 Ankyrin repeat DUF3700 PF12481.8 PSC72327.1 - 2.6e-23 82.6 0.1 1.4e-18 67.2 0.1 2.2 2 0 0 2 2 2 2 Aluminium induced protein GATase_7 PF13537.6 PSC72327.1 - 1.3e-11 44.5 0.0 2.9e-11 43.3 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 PSC72327.1 - 1.3e-06 28.7 0.0 2.3e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain SH3_19 PF18597.1 PSC72327.1 - 0.12 12.3 0.1 10 6.0 0.0 2.4 2 0 0 2 2 2 0 Myosin X N-terminal SH3 domain Spc24 PF08286.11 PSC72328.1 - 2.2e-08 34.3 0.1 4.4e-08 33.3 0.0 1.5 2 0 0 2 2 1 1 Spc24 subunit of Ndc80 Spc7 PF08317.11 PSC72328.1 - 0.00025 20.0 3.0 0.00032 19.7 3.0 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein Tropomyosin_1 PF12718.7 PSC72328.1 - 0.00088 19.4 0.7 0.00088 19.4 0.7 1.9 2 0 0 2 2 2 1 Tropomyosin like HAUS5 PF14817.6 PSC72328.1 - 0.0015 17.4 2.8 0.0016 17.3 2.8 1.2 1 0 0 1 1 1 1 HAUS augmin-like complex subunit 5 DUF1664 PF07889.12 PSC72328.1 - 0.0042 17.1 1.8 0.033 14.2 0.5 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) Tropomyosin PF00261.20 PSC72328.1 - 0.0049 16.3 5.5 0.011 15.1 1.2 2.0 2 0 0 2 2 2 1 Tropomyosin Taxilin PF09728.9 PSC72328.1 - 0.0065 15.7 2.9 0.0088 15.3 2.9 1.2 1 0 0 1 1 1 1 Myosin-like coiled-coil protein TMF_TATA_bd PF12325.8 PSC72328.1 - 0.0069 16.6 1.6 0.26 11.5 0.3 2.1 2 0 0 2 2 2 1 TATA element modulatory factor 1 TATA binding Sec34 PF04136.15 PSC72328.1 - 0.0081 16.1 0.1 0.014 15.3 0.1 1.3 1 0 0 1 1 1 1 Sec34-like family BLOC1_2 PF10046.9 PSC72328.1 - 0.0081 16.4 3.3 0.0088 16.3 1.6 1.8 1 1 1 2 2 2 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 PSC72328.1 - 0.012 16.1 3.0 0.017 15.6 1.5 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein SlyX PF04102.12 PSC72328.1 - 0.023 15.3 11.0 0.34 11.5 6.5 2.3 2 0 0 2 2 2 0 SlyX UPF0242 PF06785.11 PSC72328.1 - 0.028 14.5 0.5 0.038 14.1 0.5 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DivIC PF04977.15 PSC72328.1 - 0.03 14.1 4.7 0.03 14.1 4.7 2.2 2 0 0 2 2 2 0 Septum formation initiator DUF4763 PF15960.5 PSC72328.1 - 0.034 13.5 0.9 0.043 13.1 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4763) DUF4988 PF16378.5 PSC72328.1 - 0.036 13.8 0.1 0.072 12.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function CM_2 PF01817.21 PSC72328.1 - 0.043 14.2 4.6 0.2 12.0 1.2 2.3 2 0 0 2 2 2 0 Chorismate mutase type II DUF4407 PF14362.6 PSC72328.1 - 0.044 13.2 12.2 0.057 12.8 12.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2730 PF10805.8 PSC72328.1 - 0.046 13.8 0.3 5.7 7.1 0.1 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2730) DUF3450 PF11932.8 PSC72328.1 - 0.054 12.8 13.2 0.042 13.1 8.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Filament PF00038.21 PSC72328.1 - 0.055 13.0 4.7 0.073 12.6 4.7 1.2 1 0 0 1 1 1 0 Intermediate filament protein KxDL PF10241.9 PSC72328.1 - 0.058 13.7 1.6 8.8 6.7 1.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein DUF4795 PF16043.5 PSC72328.1 - 0.059 13.0 3.2 0.22 11.1 1.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) AAA_13 PF13166.6 PSC72328.1 - 0.059 12.0 2.4 0.076 11.7 2.4 1.2 1 0 0 1 1 1 0 AAA domain DUF948 PF06103.11 PSC72328.1 - 0.06 13.6 6.3 0.36 11.1 2.3 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Laminin_II PF06009.12 PSC72328.1 - 0.081 12.9 5.8 0.081 12.9 3.5 1.6 1 1 1 2 2 2 0 Laminin Domain II Spore_Cse60 PF10957.8 PSC72328.1 - 0.15 12.1 1.9 3.7 7.6 0.3 2.2 2 0 0 2 2 2 0 Sporulation protein Cse60 AIP3 PF03915.13 PSC72328.1 - 0.15 11.1 2.6 0.18 10.8 2.6 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 GIT_CC PF16559.5 PSC72328.1 - 0.17 11.8 4.4 0.34 10.8 4.4 1.5 1 0 0 1 1 1 0 GIT coiled-coil Rho guanine nucleotide exchange factor FlaC_arch PF05377.11 PSC72328.1 - 0.17 12.3 0.1 1.8 9.0 0.0 2.4 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) Atg14 PF10186.9 PSC72328.1 - 0.19 10.8 1.3 0.23 10.5 1.3 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Hydantoinase_B PF02538.14 PSC72328.1 - 0.26 9.7 3.9 0.21 10.0 2.5 1.4 1 1 0 1 1 1 0 Hydantoinase B/oxoprolinase Pex19 PF04614.12 PSC72328.1 - 0.27 11.0 3.3 0.37 10.5 3.3 1.2 1 0 0 1 1 1 0 Pex19 protein family CLZ PF16526.5 PSC72328.1 - 0.27 11.6 4.2 0.44 11.0 0.5 2.2 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels COG2 PF06148.11 PSC72328.1 - 0.38 10.8 4.1 0.93 9.6 0.5 2.2 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Prefoldin_2 PF01920.20 PSC72328.1 - 0.45 10.5 7.2 1.3 9.0 2.6 2.2 2 0 0 2 2 2 0 Prefoldin subunit Prefoldin PF02996.17 PSC72328.1 - 0.47 10.4 6.5 0.59 10.1 3.3 2.0 2 0 0 2 2 2 0 Prefoldin subunit DUF4358 PF14270.6 PSC72328.1 - 0.87 9.9 3.5 1.4 9.2 1.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4358) APG6_N PF17675.1 PSC72328.1 - 0.93 10.0 9.7 3.6 8.1 9.8 1.7 1 1 1 2 2 2 0 Apg6 coiled-coil region ZapA PF05164.13 PSC72328.1 - 0.95 9.9 8.5 1.9 9.0 8.3 1.6 1 1 0 1 1 1 0 Cell division protein ZapA Ax_dynein_light PF10211.9 PSC72328.1 - 0.96 9.4 6.7 0.27 11.1 2.1 1.9 1 1 1 2 2 2 0 Axonemal dynein light chain DUF4404 PF14357.6 PSC72328.1 - 1.2 9.9 6.1 0.66 10.7 2.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) DUF4140 PF13600.6 PSC72328.1 - 1.2 9.6 14.0 0.16 12.4 5.4 2.3 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) PspA_IM30 PF04012.12 PSC72328.1 - 1.5 8.4 21.2 3.3 7.2 18.1 2.0 1 1 1 2 2 2 0 PspA/IM30 family Spectrin PF00435.21 PSC72328.1 - 1.5 9.4 9.0 3 8.4 4.5 2.4 1 1 1 2 2 2 0 Spectrin repeat DUF3138 PF11336.8 PSC72328.1 - 1.7 7.1 14.6 2.7 6.5 14.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) FlgN PF05130.12 PSC72328.1 - 1.8 9.1 10.2 20 5.7 10.2 2.0 1 1 0 1 1 1 0 FlgN protein HAUS-augmin3 PF14932.6 PSC72328.1 - 4 7.0 9.0 10 5.6 8.0 1.8 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 TRAF_BIRC3_bd PF16673.5 PSC72328.1 - 6.5 6.6 9.4 4.3 7.2 3.0 2.8 2 1 1 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain F-box-like PF12937.7 PSC72329.1 - 1.4e-08 34.5 0.1 3.7e-08 33.1 0.1 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 PSC72329.1 - 8.5e-06 25.4 4.2 0.00033 20.4 0.1 3.9 4 1 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.7 PSC72329.1 - 0.00012 22.3 0.7 0.022 15.2 0.0 4.6 6 1 1 7 7 7 1 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PSC72329.1 - 0.15 11.5 0.0 0.33 10.4 0.0 1.5 1 0 0 1 1 1 0 Leucine-rich repeat WRKY PF03106.15 PSC72330.1 - 3.1e-49 165.0 11.0 4.2e-26 91.0 3.7 2.5 2 0 0 2 2 2 2 WRKY DNA -binding domain FAR1 PF03101.15 PSC72330.1 - 0.13 13.0 0.5 14 6.5 0.0 2.6 2 0 0 2 2 2 0 FAR1 DNA-binding domain HAD_2 PF13419.6 PSC72331.1 - 5e-09 36.5 0.1 1.1e-06 28.9 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 PSC72331.1 - 5.2e-08 33.5 0.3 9.6e-08 32.6 0.3 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PSC72331.1 - 8.2e-08 32.2 0.2 4.1e-07 30.0 0.1 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like Hydrolase PF00702.26 PSC72331.1 - 1.4e-06 28.7 0.4 4.2e-06 27.2 0.4 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Peptidase_M55 PF04951.13 PSC72331.1 - 0.035 13.5 0.1 0.17 11.2 0.0 2.0 2 0 0 2 2 2 0 D-aminopeptidase NIF PF03031.18 PSC72332.1 - 2.6e-08 33.8 0.0 4.1e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BTB PF00651.31 PSC72332.1 - 1.4e-06 28.4 0.0 3.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain AAA_33 PF13671.6 PSC72332.1 - 0.00076 19.7 1.0 0.098 12.8 0.2 3.0 3 1 0 3 3 3 1 AAA domain AAA_18 PF13238.6 PSC72332.1 - 0.026 15.1 0.0 0.19 12.3 0.0 2.1 1 1 1 2 2 2 0 AAA domain CBFD_NFYB_HMF PF00808.23 PSC72333.1 - 2e-13 50.4 0.3 3.2e-13 49.7 0.3 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone UPF0560 PF10577.9 PSC72333.1 - 0.26 9.8 8.8 0.36 9.3 8.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Pap_E4 PF02711.14 PSC72333.1 - 2.8 9.0 7.5 0.63 11.0 0.6 2.5 3 0 0 3 3 3 0 E4 protein FmiP_Thoc5 PF09766.9 PSC72333.1 - 2.9 7.1 7.6 1.6 8.0 5.7 1.5 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 Presenilin PF01080.17 PSC72333.1 - 3.1 6.4 7.2 4.5 5.9 7.2 1.2 1 0 0 1 1 1 0 Presenilin Coilin_N PF15862.5 PSC72333.1 - 5.8 6.7 10.2 8.1 6.3 7.5 2.0 2 0 0 2 2 2 0 Coilin N-terminus LSM PF01423.22 PSC72334.1 - 1.3e-12 47.2 0.0 2.2e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 LSM domain Spt20 PF12090.8 PSC72334.1 - 0.26 10.9 24.1 0.36 10.4 24.1 1.2 1 0 0 1 1 1 0 Spt20 family Pex14_N PF04695.13 PSC72334.1 - 0.62 10.7 18.9 1.2 9.8 18.9 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 PSC72334.1 - 0.81 9.6 28.1 1.1 9.2 28.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 PSC72334.1 - 1.1 10.2 5.0 2.4 9.2 5.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Suf PF05843.14 PSC72334.1 - 2.6 7.9 7.9 6.3 6.7 8.4 1.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) UPF0560 PF10577.9 PSC72334.1 - 6.4 5.1 14.9 8.5 4.7 14.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Histone PF00125.24 PSC72335.1 - 2.9e-54 183.0 1.9 3.2e-54 182.8 1.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 PSC72335.1 - 0.00013 22.5 1.7 0.00016 22.2 1.7 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 PSC72335.1 - 0.00045 20.5 0.0 0.00069 20.0 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein CENP-T_C PF15511.6 PSC72335.1 - 0.00049 20.2 0.5 0.00074 19.6 0.1 1.6 2 0 0 2 2 2 1 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 PSC72335.1 - 0.0052 17.1 0.0 0.01 16.1 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PSC72335.1 - 0.016 15.3 0.1 0.031 14.3 0.0 1.5 2 0 0 2 2 2 0 Transcription initiation factor IID, 31kD subunit Cullin_binding PF03556.15 PSC72336.1 - 1.4e-34 119.1 1.5 3e-34 118.0 1.5 1.6 1 0 0 1 1 1 1 Cullin binding UBA_4 PF14555.6 PSC72336.1 - 2.8e-11 43.1 0.0 5.3e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Lipase_3 PF01764.25 PSC72336.1 - 3.5e-10 39.9 0.0 3.3e-08 33.5 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) TAP_C PF03943.13 PSC72336.1 - 0.11 12.2 0.0 0.25 11.0 0.0 1.6 1 0 0 1 1 1 0 TAP C-terminal domain DNA_pol_A PF00476.20 PSC72337.1 - 1e-85 288.1 0.0 1.7e-85 287.4 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase family A TTL PF03133.15 PSC72338.1 - 1.8e-23 83.1 0.0 2.3e-22 79.5 0.0 2.0 1 1 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 PSC72338.1 - 0.006 15.9 0.0 0.013 14.8 0.0 1.5 1 0 0 1 1 1 1 YheC/D like ATP-grasp HTH_32 PF13565.6 PSC72338.1 - 0.25 12.0 1.5 1.8 9.2 0.0 3.1 3 0 0 3 3 3 0 Homeodomain-like domain URO-D PF01208.17 PSC72339.1 - 4.4e-110 368.1 0.0 5.1e-110 367.9 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) DUF5641 PF18701.1 PSC72339.1 - 0.075 13.2 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5641) AMP-binding PF00501.28 PSC72339.1 - 0.092 11.3 0.0 0.14 10.7 0.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme Glucosamine_iso PF01182.20 PSC72340.1 - 4.2e-42 144.5 0.0 5.7e-42 144.1 0.0 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase HCV_NS5a_C PF12941.7 PSC72341.1 - 0.044 13.6 0.6 0.064 13.1 0.6 1.2 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region SR-25 PF10500.9 PSC72341.1 - 0.31 10.6 7.0 0.43 10.1 7.0 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NDUFA12 PF05071.16 PSC72342.1 - 8.4e-12 45.8 0.1 9.9e-12 45.5 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 NDUFA12 PF05071.16 PSC72343.1 - 8.4e-12 45.8 0.1 9.9e-12 45.5 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 ACC_epsilon PF13822.6 PSC72344.1 - 9.5 7.0 17.4 2.9 8.6 3.2 2.7 3 0 0 3 3 3 0 Acyl-CoA carboxylase epsilon subunit ETF_QO PF05187.13 PSC72345.1 - 5.9e-45 151.7 0.0 9.6e-45 151.0 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S NAD_binding_8 PF13450.6 PSC72345.1 - 9.6e-06 25.8 1.1 2.2e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 PSC72345.1 - 2.5e-05 23.6 0.0 0.00014 21.2 0.0 2.1 3 0 0 3 3 3 1 Thi4 family FAD_binding_2 PF00890.24 PSC72345.1 - 2.5e-05 23.5 1.1 0.00016 20.9 0.5 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 PSC72345.1 - 4.9e-05 23.1 0.4 0.014 15.0 0.2 2.3 1 1 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 PSC72345.1 - 0.00072 18.4 0.2 0.001 17.9 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 PSC72345.1 - 0.00085 18.5 0.2 0.0015 17.6 0.2 1.4 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_2 PF07992.14 PSC72345.1 - 0.0012 18.1 0.0 0.0018 17.5 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PSC72345.1 - 0.0021 17.4 0.3 0.003 16.9 0.3 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PSC72345.1 - 0.0069 16.4 0.0 0.013 15.4 0.0 1.5 1 0 0 1 1 1 1 FAD-NAD(P)-binding Fer4_7 PF12838.7 PSC72345.1 - 0.0092 16.6 0.9 0.021 15.4 0.9 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain FAD_binding_3 PF01494.19 PSC72345.1 - 0.069 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox PF00070.27 PSC72345.1 - 0.11 13.1 0.0 14 6.3 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PSC72345.1 - 0.19 11.0 0.1 0.29 10.4 0.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase EIF_2_alpha PF07541.12 PSC72346.1 - 2.2e-36 124.5 0.0 5e-36 123.3 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit PsbW PF07123.12 PSC72346.1 - 1.4e-20 73.6 0.0 3.8e-20 72.3 0.0 1.7 1 0 0 1 1 1 1 Photosystem II reaction centre W protein (PsbW) S1 PF00575.23 PSC72346.1 - 4.1e-13 49.5 0.2 9.4e-13 48.3 0.2 1.7 1 0 0 1 1 1 1 S1 RNA binding domain DUF4233 PF14017.6 PSC72346.1 - 0.013 15.9 0.0 0.027 14.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) CENP-T_C PF15511.6 PSC72347.1 - 2e-08 34.3 0.1 2.5e-08 34.0 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PSC72347.1 - 0.00015 22.1 0.1 0.0002 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein TAF PF02969.17 PSC72347.1 - 0.00022 21.3 0.1 0.00031 20.8 0.1 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) Bromo_TP PF07524.13 PSC72347.1 - 0.0011 18.9 0.1 0.0017 18.4 0.1 1.2 1 0 0 1 1 1 1 Bromodomain associated CBFD_NFYB_HMF PF00808.23 PSC72347.1 - 0.0013 19.0 0.0 0.0022 18.3 0.0 1.5 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PSC72347.1 - 0.0015 18.9 0.1 0.0017 18.8 0.1 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TFIID-31kDa PF02291.15 PSC72347.1 - 0.033 14.3 0.0 0.037 14.1 0.0 1.1 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit HSP70 PF00012.20 PSC72348.1 - 0 1092.9 13.6 2.3e-257 855.0 2.8 4.8 4 1 0 4 4 4 3 Hsp70 protein MreB_Mbl PF06723.13 PSC72348.1 - 9.6e-26 90.4 3.9 5e-13 48.6 0.0 4.3 5 0 0 5 5 5 2 MreB/Mbl protein FGGY_C PF02782.16 PSC72348.1 - 4e-10 39.8 0.1 0.00016 21.5 0.2 2.7 2 0 0 2 2 2 2 FGGY family of carbohydrate kinases, C-terminal domain StbA PF06406.11 PSC72348.1 - 0.0008 18.7 0.2 0.52 9.5 0.1 2.5 2 0 0 2 2 2 2 StbA protein DDR PF08841.10 PSC72348.1 - 0.083 11.9 6.0 2.7 6.9 0.1 3.2 3 0 0 3 3 3 0 Diol dehydratase reactivase ATPase-like domain Asp_protease_2 PF13650.6 PSC72349.1 - 3e-16 59.8 0.0 1.6e-10 41.5 0.0 2.9 2 1 0 2 2 2 2 Aspartyl protease gag-asp_proteas PF13975.6 PSC72349.1 - 3.6e-10 40.3 0.0 6.7e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Bromodomain PF00439.25 PSC72350.1 - 6.2e-20 71.1 0.1 1.4e-19 70.0 0.1 1.6 1 0 0 1 1 1 1 Bromodomain peroxidase PF00141.23 PSC72350.1 - 4.2e-19 69.2 0.0 9.6e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 Peroxidase PEHE PF15275.6 PSC72350.1 - 6.8e-06 26.7 0.1 6.8e-06 26.7 0.1 3.3 2 1 0 2 2 2 1 PEHE domain Pkinase PF00069.25 PSC72353.1 - 1.7e-73 247.2 0.0 2e-73 247.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC72353.1 - 4.4e-44 150.7 0.0 5.5e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC72353.1 - 1.1e-05 24.9 0.0 0.0001 21.7 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.11 PSC72353.1 - 0.12 11.4 0.0 0.19 10.7 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 FTA2 PF13095.6 PSC72353.1 - 0.13 11.9 0.1 4.9 6.7 0.0 2.1 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Fe_hyd_lg_C PF02906.14 PSC72354.1 - 2.8e-59 200.7 0.0 6.2e-51 173.4 0.0 2.1 2 0 0 2 2 2 2 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 PSC72354.1 - 3.4e-05 23.8 0.0 5.6e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 Iron hydrogenase small subunit Arf PF00025.21 PSC72355.1 - 2.2e-67 225.9 0.0 2.5e-67 225.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 PSC72355.1 - 2e-12 46.9 0.0 2.6e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 PSC72355.1 - 3e-12 46.8 0.0 3.9e-12 46.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 PSC72355.1 - 1.3e-10 41.0 0.3 1.6e-05 24.3 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 PSC72355.1 - 4.3e-10 39.4 0.0 5.2e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 PSC72355.1 - 7.6e-09 35.7 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PSC72355.1 - 2e-08 33.9 0.0 2.4e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 PSC72355.1 - 0.008 15.7 0.1 0.019 14.5 0.0 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 PSC72355.1 - 0.0083 15.7 0.0 0.1 12.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain TniB PF05621.11 PSC72355.1 - 0.047 13.1 0.0 0.081 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein PPK2 PF03976.14 PSC72355.1 - 0.054 13.0 0.1 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) HCO3_cotransp PF00955.21 PSC72356.1 - 1.8e-67 228.3 0.5 1.2e-26 93.6 0.0 3.1 2 1 1 3 3 3 3 HCO3- transporter family DnaJ PF00226.31 PSC72356.1 - 2.7e-19 69.0 0.3 5e-19 68.2 0.3 1.5 1 0 0 1 1 1 1 DnaJ domain RRM_1 PF00076.22 PSC72356.1 - 0.00096 18.9 0.0 0.0027 17.5 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FlgN PF05130.12 PSC72356.1 - 0.11 13.1 10.3 0.27 11.7 10.3 1.7 1 0 0 1 1 1 0 FlgN protein SecA_DEAD PF07517.14 PSC72357.1 - 8.4e-126 419.1 0.4 2.2e-125 417.7 0.1 1.7 2 0 0 2 2 2 1 SecA DEAD-like domain SecA_SW PF07516.13 PSC72357.1 - 3.4e-53 180.7 0.7 1e-52 179.1 0.7 1.9 1 0 0 1 1 1 1 SecA Wing and Scaffold domain SecA_PP_bind PF01043.20 PSC72357.1 - 4.3e-38 130.4 0.2 1.8e-36 125.2 0.1 2.7 2 0 0 2 2 2 1 SecA preprotein cross-linking domain DEAD PF00270.29 PSC72357.1 - 1.8e-06 27.8 0.0 5.1e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC72357.1 - 0.025 14.9 0.3 0.18 12.1 0.0 2.5 3 0 0 3 3 3 0 Helicase conserved C-terminal domain DNase-RNase PF02577.14 PSC72358.1 - 1.8e-36 124.6 0.0 3e-36 123.9 0.0 1.3 1 0 0 1 1 1 1 Bifunctional nuclease UVR PF02151.19 PSC72358.1 - 3.7e-09 36.0 7.7 2e-05 24.2 0.4 2.5 2 0 0 2 2 2 2 UvrB/uvrC motif Pkinase PF00069.25 PSC72358.1 - 0.00044 19.7 0.0 0.00073 19.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC72358.1 - 0.023 14.0 0.0 0.042 13.1 0.0 1.4 1 0 0 1 1 1 0 Protein tyrosine kinase DUF3168 PF11367.8 PSC72358.1 - 0.31 11.2 2.3 0.4 10.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3168) Glyco_hydro_1 PF00232.18 PSC72359.1 - 5.5e-93 311.9 0.0 6.1e-93 311.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 1 LETM1 PF07766.13 PSC72360.1 - 4e-16 59.2 0.0 9.4e-16 58.0 0.0 1.5 1 0 0 1 1 1 1 LETM1-like protein Enkurin PF13864.6 PSC72360.1 - 0.022 15.2 1.4 0.022 15.2 1.4 3.1 4 0 0 4 4 4 0 Calmodulin-binding PKHD_C PF18331.1 PSC72360.1 - 0.15 12.1 0.2 2.7 8.2 0.0 2.8 2 0 0 2 2 2 0 PKHD-type hydroxylase C-terminal domain Rhomboid PF01694.22 PSC72361.1 - 2e-24 86.3 11.8 2e-24 86.3 11.8 2.2 2 0 0 2 2 2 1 Rhomboid family Peptidase_M48 PF01435.18 PSC72361.1 - 3.3e-16 59.6 0.0 1e-15 58.1 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M48 AIG2_2 PF13772.6 PSC72361.1 - 0.00032 21.0 0.0 0.00061 20.1 0.0 1.5 1 0 0 1 1 1 1 AIG2-like family Steroid_dh PF02544.16 PSC72362.1 - 1.1e-27 96.9 1.9 2.1e-27 96.0 1.9 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase DUF1295 PF06966.12 PSC72362.1 - 0.079 12.5 1.4 0.16 11.5 1.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1295) ubiquitin PF00240.23 PSC72362.1 - 0.2 11.4 0.0 0.66 9.8 0.0 1.8 1 1 0 1 1 1 0 Ubiquitin family PEMT PF04191.13 PSC72362.1 - 0.57 10.6 9.1 2.4 8.6 0.2 2.6 3 0 0 3 3 3 0 Phospholipid methyltransferase PHO4 PF01384.20 PSC72363.1 - 1.1e-68 231.8 12.6 2.7e-50 171.3 3.3 2.2 2 0 0 2 2 2 2 Phosphate transporter family SurA_N_3 PF13624.6 PSC72363.1 - 0.38 10.5 2.7 7.9 6.2 0.1 2.5 2 0 0 2 2 2 0 SurA N-terminal domain Rubis-subs-bind PF09273.11 PSC72364.1 - 4.7e-18 66.1 0.1 9.7e-18 65.1 0.0 1.6 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.28 PSC72364.1 - 1.1e-09 38.9 0.0 2.1e-09 38.0 0.0 1.5 1 0 0 1 1 1 1 SET domain DUF4719 PF15843.5 PSC72364.1 - 0.29 11.2 2.7 0.58 10.2 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4719) DUF2749 PF10907.8 PSC72364.1 - 2.8 8.2 4.9 1.6 9.0 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2749) G-patch PF01585.23 PSC72365.1 - 6.8e-11 41.9 5.7 6.8e-11 41.9 5.7 2.3 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 PSC72365.1 - 6e-05 23.0 3.3 6e-05 23.0 3.3 2.7 3 0 0 3 3 3 1 G-patch domain OAD_gamma PF04277.13 PSC72365.1 - 1.3 9.6 0.0 1.3 9.6 0.0 4.2 3 1 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain RRM_1 PF00076.22 PSC72366.1 - 1.2e-25 89.1 0.2 2e-13 49.9 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PSC72366.1 - 4.8e-08 33.0 0.0 0.0012 18.9 0.0 2.7 2 1 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 PSC72366.1 - 0.0056 16.5 0.0 0.54 10.1 0.0 2.9 3 0 0 3 3 3 1 Occluded RNA-recognition motif OB_RNB PF08206.11 PSC72366.1 - 0.079 12.7 0.0 4.5 7.0 0.0 2.4 2 0 0 2 2 2 0 Ribonuclease B OB domain TrbH PF07283.11 PSC72366.1 - 0.14 12.3 0.0 0.35 11.1 0.0 1.6 2 0 0 2 2 2 0 Conjugal transfer protein TrbH Spo7_2_N PF15407.6 PSC72366.1 - 0.18 11.4 0.0 0.56 9.9 0.0 1.7 2 0 0 2 2 2 0 Sporulation protein family 7 LRR_8 PF13855.6 PSC72367.1 - 9.8e-11 41.3 2.6 0.041 13.7 0.0 6.0 6 1 1 7 7 7 4 Leucine rich repeat LRR_4 PF12799.7 PSC72367.1 - 1.8e-07 31.3 0.9 0.15 12.6 0.1 6.4 6 2 0 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PSC72367.1 - 3.7 8.5 10.5 12 6.9 0.2 5.7 6 0 0 6 6 6 0 Leucine Rich Repeat p25-alpha PF05517.12 PSC72369.1 - 1.7e-30 106.3 0.0 8.1e-15 55.3 0.0 3.0 2 0 0 2 2 2 2 p25-alpha Sod_Fe_C PF02777.18 PSC72370.1 - 6.4e-36 122.6 0.0 1e-35 122.0 0.0 1.3 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 PSC72370.1 - 3.2e-32 110.8 0.1 5.5e-32 110.1 0.1 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain Myb_DNA-binding PF00249.31 PSC72371.1 - 8.6e-10 38.7 4.9 0.00015 21.9 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC72371.1 - 5.8e-07 29.7 0.9 0.00079 19.6 0.6 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Prismane PF03063.20 PSC72373.1 - 1.8e-147 492.1 0.0 2.1e-147 491.9 0.0 1.0 1 0 0 1 1 1 1 Prismane/CO dehydrogenase family SBP PF03110.14 PSC72375.1 - 1.2e-22 80.0 8.1 2.5e-22 78.9 8.1 1.5 1 0 0 1 1 1 1 SBP domain SBP PF03110.14 PSC72376.1 - 1.2e-22 80.0 8.1 2.5e-22 78.9 8.1 1.5 1 0 0 1 1 1 1 SBP domain Thioredoxin PF00085.20 PSC72377.1 - 8.6e-15 54.6 0.0 4.2e-14 52.4 0.0 2.0 2 0 0 2 2 2 1 Thioredoxin DUF629 PF04780.12 PSC72377.1 - 1.7e-06 26.8 0.0 4.7e-06 25.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF629) zf_CCCH_4 PF18345.1 PSC72377.1 - 8.5e-05 22.5 4.3 0.00016 21.6 4.3 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 PSC72377.1 - 0.0029 17.4 4.2 0.0029 17.4 4.2 1.8 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH PF00642.24 PSC72377.1 - 0.026 14.4 0.9 0.052 13.5 0.9 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) AP3D1 PF06375.11 PSC72377.1 - 0.043 14.1 1.4 0.1 12.8 1.4 1.5 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 zf-Di19 PF05605.12 PSC72377.1 - 0.18 12.1 2.2 0.38 11.1 2.2 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding TPP_enzyme_N PF02776.18 PSC72378.1 - 3.7e-28 98.3 1.2 3.7e-28 98.3 1.2 2.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 PSC72378.1 - 2.2e-24 86.0 5.8 3.6e-23 82.0 0.0 3.2 4 1 0 4 4 4 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain p25-alpha PF05517.12 PSC72379.1 - 4.7e-33 114.6 0.0 3.4e-16 59.8 0.0 2.2 2 0 0 2 2 2 2 p25-alpha CAF1A PF12253.8 PSC72380.1 - 7.7e-11 42.0 3.4 7.7e-11 42.0 3.4 2.5 2 1 0 2 2 2 1 Chromatin assembly factor 1 subunit A Homeodomain PF00046.29 PSC72380.1 - 2.1e-09 37.1 0.1 5.5e-09 35.7 0.1 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 PSC72380.1 - 0.00014 21.7 0.0 0.00063 19.6 0.0 2.1 2 0 0 2 2 2 1 Homeobox KN domain Macoilin PF09726.9 PSC72380.1 - 1 7.8 17.2 1.7 7.1 17.2 1.3 1 0 0 1 1 1 0 Macoilin family tRNA_synt_2f PF02092.17 PSC72381.1 - 7e-169 563.2 0.0 8.6e-169 562.9 0.0 1.1 1 0 0 1 1 1 1 Glycyl-tRNA synthetase beta subunit tRNA-synt_2e PF02091.15 PSC72381.1 - 9.3e-128 425.3 0.0 1.3e-127 424.8 0.0 1.2 1 0 0 1 1 1 1 Glycyl-tRNA synthetase alpha subunit DALR_1 PF05746.15 PSC72381.1 - 0.0056 16.8 0.0 0.019 15.2 0.0 1.9 1 0 0 1 1 1 1 DALR anticodon binding domain Sugar_tr PF00083.24 PSC72382.1 - 5.3e-56 190.4 2.9 1.1e-54 186.1 0.4 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter RRM_1 PF00076.22 PSC72382.1 - 6.6e-14 51.5 0.0 1.3e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 PSC72382.1 - 7.9e-11 41.5 20.1 1.5e-10 40.6 19.0 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily RL PF17797.1 PSC72382.1 - 0.048 13.6 0.2 0.1 12.6 0.2 1.5 1 0 0 1 1 1 0 RL domain Arf PF00025.21 PSC72383.1 - 4.6e-74 247.6 0.0 7e-74 247.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 PSC72383.1 - 7.3e-13 48.8 0.0 1.3e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PSC72383.1 - 1.3e-10 41.1 0.0 2.1e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 PSC72383.1 - 2e-09 37.2 0.0 3.1e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 PSC72383.1 - 8.4e-09 35.0 0.0 1.7e-06 27.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 PSC72383.1 - 1.8e-07 30.8 0.0 2.5e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Myb_DNA-bind_4 PF13837.6 PSC72383.1 - 0.00034 20.9 0.3 0.00092 19.5 0.3 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MMR_HSR1 PF01926.23 PSC72383.1 - 0.00041 20.4 0.0 0.00091 19.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Myb_DNA-binding PF00249.31 PSC72383.1 - 0.0084 16.3 1.0 0.27 11.5 0.2 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC72383.1 - 0.037 14.3 0.0 0.091 13.0 0.0 1.8 1 1 0 1 1 1 0 Myb-like DNA-binding domain Arf PF00025.21 PSC72384.1 - 4.7e-74 247.6 0.0 7.1e-74 247.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 PSC72384.1 - 7.3e-13 48.8 0.0 1.4e-12 47.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 PSC72384.1 - 1.3e-10 41.1 0.0 2.1e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 PSC72384.1 - 2e-09 37.2 0.0 3.1e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 PSC72384.1 - 8.6e-09 35.0 0.0 1.7e-06 27.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 PSC72384.1 - 1.8e-07 30.8 0.0 2.6e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Myb_DNA-bind_4 PF13837.6 PSC72384.1 - 0.00034 20.9 0.3 0.00093 19.5 0.3 1.7 1 0 0 1 1 1 1 Myb/SANT-like DNA-binding domain MMR_HSR1 PF01926.23 PSC72384.1 - 0.00042 20.4 0.0 0.00092 19.3 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Myb_DNA-binding PF00249.31 PSC72384.1 - 0.0086 16.2 1.0 0.27 11.5 0.2 2.7 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC72384.1 - 0.037 14.3 0.0 0.092 13.0 0.0 1.8 1 1 0 1 1 1 0 Myb-like DNA-binding domain DUF563 PF04577.14 PSC72385.1 - 1.7e-83 279.9 8.8 1.3e-17 64.6 0.0 5.5 5 0 0 5 5 5 5 Protein of unknown function (DUF563) SnoaL PF07366.12 PSC72385.1 - 1.4e-11 44.2 0.3 3.1e-11 43.1 0.3 1.6 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase Chlorophyllase2 PF12740.7 PSC72385.1 - 7e-05 21.9 2.7 0.024 13.6 0.3 3.1 3 0 0 3 3 3 2 Chlorophyllase enzyme DDHD PF02862.17 PSC72385.1 - 0.083 13.0 0.2 0.17 12.0 0.2 1.4 1 0 0 1 1 1 0 DDHD domain MMU163 PF17119.5 PSC72385.1 - 0.14 11.3 0.0 0.14 11.3 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis Tim54 PF11711.8 PSC72385.1 - 0.18 10.6 4.3 0.29 9.9 4.3 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 eIF-3_zeta PF05091.12 PSC72385.1 - 0.62 9.0 4.7 1.1 8.2 4.7 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Pex14_N PF04695.13 PSC72385.1 - 0.91 10.2 14.9 2.7 8.6 8.5 3.1 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SpoIIP PF07454.11 PSC72385.1 - 2.8 7.3 8.7 4.8 6.5 8.7 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) CPSF100_C PF13299.6 PSC72385.1 - 2.8 8.1 8.5 5.5 7.1 8.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal HgmA PF04209.13 PSC72387.1 - 4.3e-208 691.2 0.1 5.8e-208 690.8 0.1 1.2 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase RINGv PF12906.7 PSC72387.1 - 2.6e-11 43.5 9.2 5.8e-11 42.3 9.2 1.7 1 0 0 1 1 1 1 RING-variant domain CUE PF02845.16 PSC72387.1 - 1.4e-07 31.1 0.0 3.6e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 CUE domain zf-MYND PF01753.18 PSC72387.1 - 1.9e-06 27.8 10.0 6.7e-06 26.1 10.0 2.0 1 0 0 1 1 1 1 MYND finger SUIM_assoc PF16619.5 PSC72387.1 - 0.0067 16.5 5.5 0.46 10.6 1.2 2.6 2 0 0 2 2 2 2 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 PSC72387.1 - 3.5 7.5 9.7 0.85 9.5 2.9 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 PSC72388.1 - 0.0029 17.8 0.9 0.0041 17.3 0.9 1.4 1 0 0 1 1 1 1 DDHD domain eIF-3c_N PF05470.12 PSC72388.1 - 0.027 12.8 1.3 0.033 12.5 1.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Het-C PF07217.11 PSC72388.1 - 0.098 11.2 5.4 0.14 10.7 5.4 1.2 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C UPF0560 PF10577.9 PSC72388.1 - 0.42 9.1 12.3 0.6 8.5 12.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 V_ATPase_I PF01496.19 PSC72388.1 - 0.65 7.8 6.0 0.76 7.6 6.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 PSC72388.1 - 1.9 7.1 6.1 2.6 6.7 6.1 1.2 1 0 0 1 1 1 0 Presenilin F-protein PF00469.20 PSC72388.1 - 3.8 7.1 9.4 6.6 6.3 9.4 1.3 1 0 0 1 1 1 0 Negative factor, (F-Protein) or Nef FmiP_Thoc5 PF09766.9 PSC72388.1 - 4.4 6.5 16.1 0.7 9.1 1.4 2.1 2 0 0 2 2 2 0 Fms-interacting protein/Thoc5 DUF4834 PF16118.5 PSC72388.1 - 5.1 8.1 6.5 12 6.9 6.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 PSC72388.1 - 5.2 5.9 18.1 0.074 12.0 10.9 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Phage_GPO PF05929.11 PSC72388.1 - 8.8 5.9 18.2 2.7 7.5 12.8 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase adh_short_C2 PF13561.6 PSC72389.1 - 3.6e-45 154.3 7.6 6.6e-43 146.9 7.6 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PSC72389.1 - 4.6e-37 127.4 7.5 3.8e-36 124.4 7.5 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PSC72389.1 - 5.6e-08 32.9 0.9 1.1e-05 25.5 0.9 2.2 1 1 0 1 1 1 1 KR domain HisG_C PF08029.11 PSC72389.1 - 0.00019 21.5 0.1 0.00049 20.2 0.1 1.7 1 0 0 1 1 1 1 HisG, C-terminal domain DUF440 PF04269.12 PSC72389.1 - 0.13 12.5 0.2 0.23 11.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF440 Ribul_P_3_epim PF00834.19 PSC72390.1 - 4.8e-87 290.5 0.1 5.7e-87 290.2 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family NanE PF04131.14 PSC72390.1 - 0.0072 15.5 0.2 0.024 13.8 0.2 1.8 1 1 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase OMPdecase PF00215.24 PSC72390.1 - 0.084 12.5 0.1 0.16 11.5 0.1 1.7 1 1 0 1 1 1 0 Orotidine 5'-phosphate decarboxylase / HUMPS family IMPDH PF00478.25 PSC72390.1 - 0.088 11.8 0.8 27 3.6 0.1 2.9 3 0 0 3 3 3 0 IMP dehydrogenase / GMP reductase domain Sp38 PF07354.12 PSC72390.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.3 1 0 0 1 1 1 0 Zona-pellucida-binding protein (Sp38) NMT1 PF09084.11 PSC72392.1 - 4e-43 147.9 0.0 7.5e-43 147.0 0.0 1.4 1 0 0 1 1 1 1 NMT1/THI5 like WD40 PF00400.32 PSC72392.1 - 4.4e-12 46.3 6.3 0.035 15.0 0.1 6.0 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC72392.1 - 7.6e-07 29.4 0.0 0.0079 16.5 0.1 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PSC72392.1 - 0.00085 18.1 0.3 0.029 13.0 0.1 2.3 2 0 0 2 2 2 1 Nucleoporin Nup120/160 2-ph_phosp PF04029.14 PSC72392.1 - 0.041 13.0 0.2 0.088 12.0 0.2 1.4 1 0 0 1 1 1 0 2-phosphosulpholactate phosphatase IspD PF01128.19 PSC72393.1 - 3.3e-57 193.8 0.0 4.6e-57 193.3 0.0 1.2 1 0 0 1 1 1 1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 2OG-FeII_Oxy_3 PF13640.6 PSC72393.1 - 1.4e-13 51.5 0.0 2.8e-13 50.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily NTP_transf_3 PF12804.7 PSC72393.1 - 5.5e-10 39.8 0.4 5.5e-10 39.8 0.4 1.8 2 0 0 2 2 2 1 MobA-like NTP transferase domain CP12 PF02672.15 PSC72393.1 - 0.0017 19.1 0.3 0.0041 17.9 0.3 1.6 1 0 0 1 1 1 1 CP12 domain ShK PF01549.24 PSC72393.1 - 0.22 12.1 8.1 1.4 9.6 8.1 2.3 1 1 0 1 1 1 0 ShK domain-like Glyco_hydro_85 PF03644.13 PSC72394.1 - 7.1e-81 271.9 0.0 9e-81 271.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 Methyltransf_21 PF05050.12 PSC72395.1 - 2.6e-10 40.6 0.0 3.6e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain DUF3197 PF11432.8 PSC72395.1 - 0.083 12.8 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3197) Shadoo PF14999.6 PSC72395.1 - 0.6 10.2 5.1 72 3.5 5.1 2.4 1 1 0 1 1 1 0 Shadow of prion protein, neuroprotective Pkinase_Tyr PF07714.17 PSC72396.1 - 4.8e-54 183.4 0.0 6.9e-54 182.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC72396.1 - 5.4e-48 163.7 0.0 8.8e-48 163.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TatD_DNase PF01026.21 PSC72396.1 - 8.3e-45 153.1 0.0 1.5e-44 152.3 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase PB1 PF00564.24 PSC72396.1 - 5.7e-07 29.4 0.0 2.4e-06 27.4 0.0 2.0 2 0 0 2 2 2 1 PB1 domain Kinase-like PF14531.6 PSC72396.1 - 0.00026 20.4 0.0 0.00046 19.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PSC72396.1 - 0.0027 16.5 0.0 0.0046 15.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase POTRA_3 PF17287.2 PSC72396.1 - 0.024 14.1 0.0 0.067 12.7 0.0 1.7 1 0 0 1 1 1 0 POTRA domain MS_channel PF00924.18 PSC72397.1 - 7.3e-20 71.4 1.6 7.3e-20 71.4 1.6 1.5 2 0 0 2 2 2 1 Mechanosensitive ion channel Rhodanese PF00581.20 PSC72398.1 - 5.7e-07 30.0 0.0 1.2e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain FdhE PF04216.12 PSC72398.1 - 0.062 13.2 1.0 8.8 6.1 1.7 2.4 2 0 0 2 2 2 0 Protein involved in formate dehydrogenase formation DUF760 PF05542.11 PSC72399.1 - 3.7e-21 75.3 3.8 1.5e-20 73.3 0.6 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF760) WD40 PF00400.32 PSC72399.1 - 1.1e-06 29.3 5.7 0.14 13.1 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat FlxA PF14282.6 PSC72399.1 - 8.1 6.5 11.3 0.39 10.7 1.9 2.3 2 0 0 2 2 2 0 FlxA-like protein LNP1 PF15419.6 PSC72399.1 - 8.1 6.6 6.1 0.75 10.0 1.3 1.7 2 0 0 2 2 2 0 Leukemia NUP98 fusion partner 1 Methyltransf_3 PF01596.17 PSC72400.1 - 2.3e-11 43.3 0.0 4e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 PSC72400.1 - 1.5e-07 32.4 0.1 1.1e-06 29.6 0.0 2.6 2 1 1 3 3 3 1 Methyltransferase domain SAM_2 PF07647.17 PSC72400.1 - 5.4e-06 26.4 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PSC72400.1 - 0.00043 20.7 0.0 0.00074 19.9 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) fn3 PF00041.21 PSC72400.1 - 0.0026 18.1 0.0 0.0059 16.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III domain EF-hand_6 PF13405.6 PSC72400.1 - 0.038 13.9 0.1 0.72 9.9 0.0 2.4 2 0 0 2 2 2 0 EF-hand domain EF-hand_5 PF13202.6 PSC72400.1 - 0.081 12.5 0.3 0.25 10.9 0.2 1.9 2 0 0 2 2 2 0 EF hand PCMT PF01135.19 PSC72400.1 - 0.088 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Spore_coat_CotO PF14153.6 PSC72401.1 - 3.5 7.5 9.8 0.65 9.9 0.6 2.3 2 0 0 2 2 2 0 Spore coat protein CotO Glyco_hydro_46 PF01374.18 PSC72402.1 - 1.1e-44 152.6 0.0 1.4e-44 152.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Chitin_bind_1 PF00187.19 PSC72402.1 - 1e-07 32.3 16.3 1e-07 32.3 16.3 1.7 2 0 0 2 2 2 1 Chitin recognition protein Rhodanese PF00581.20 PSC72404.1 - 5.7e-11 42.9 0.0 1e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 Rhodanese-like domain zinc_ribbon_2 PF13240.6 PSC72405.1 - 0.1 12.4 0.2 0.17 11.7 0.2 1.3 1 0 0 1 1 1 0 zinc-ribbon domain PPR_2 PF13041.6 PSC72407.1 - 3.1e-11 43.3 0.0 0.11 12.7 0.0 6.2 6 0 0 6 6 6 3 PPR repeat family PPR_3 PF13812.6 PSC72407.1 - 1.1e-10 41.4 0.0 0.055 13.6 0.0 4.6 3 1 2 5 5 5 3 Pentatricopeptide repeat domain PPR_long PF17177.4 PSC72407.1 - 7.6e-08 32.0 2.0 0.012 15.0 0.0 4.1 2 1 2 4 4 4 2 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 PSC72407.1 - 0.0001 22.3 0.0 3 8.3 0.0 5.0 5 0 0 5 5 5 1 PPR repeat Presenilin PF01080.17 PSC72407.1 - 3 6.5 5.0 1.7 7.3 0.2 2.1 2 0 0 2 2 2 0 Presenilin TFIIA PF03153.13 PSC72407.1 - 4.7 7.1 34.7 0.017 15.1 8.4 2.9 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Suf PF05843.14 PSC72407.1 - 6.2 6.7 12.8 8.7 6.2 5.0 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TatD_DNase PF01026.21 PSC72408.1 - 7.9e-47 159.8 0.0 2.5e-46 158.1 0.0 1.7 1 1 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.14 PSC72408.1 - 0.022 14.5 2.5 0.16 11.7 2.5 2.2 1 1 0 1 1 1 0 Amidohydrolase DUF3570 PF12094.8 PSC72408.1 - 0.25 10.1 0.0 0.33 9.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3570) zf-RanBP PF00641.18 PSC72409.1 - 4.4e-47 157.0 109.7 3.7e-08 32.6 6.2 9.3 9 0 0 9 9 9 9 Zn-finger in Ran binding protein and others TackOD1 PF18551.1 PSC72409.1 - 0.065 12.9 51.9 0.88 9.2 0.4 8.6 9 0 0 9 9 9 0 Thaumarchaeal output domain 1 zinc_ribbon_10 PF10058.9 PSC72409.1 - 0.15 11.8 27.1 19 5.1 0.0 9.1 10 0 0 10 10 10 0 Predicted integral membrane zinc-ribbon metal-binding protein Pkinase_Tyr PF07714.17 PSC72410.1 - 3.3e-60 203.5 0.0 4.1e-60 203.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC72410.1 - 1.6e-50 172.0 0.0 2e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 PSC72410.1 - 8.7e-06 25.8 0.2 3.6e-05 23.8 0.2 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PSC72410.1 - 1.2e-05 24.8 0.0 0.0032 16.8 0.0 2.1 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 PSC72410.1 - 0.00087 18.2 0.0 0.0012 17.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase CBM_2 PF00553.19 PSC72410.1 - 0.0089 16.3 1.3 0.15 12.4 0.0 2.3 2 0 0 2 2 2 1 Cellulose binding domain Haspin_kinase PF12330.8 PSC72410.1 - 0.11 11.4 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain GCFC PF07842.12 PSC72411.1 - 1.9e-76 257.3 1.9 4.1e-76 256.2 1.9 1.6 1 0 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 PSC72411.1 - 3.2e-18 66.0 4.0 3.2e-18 66.0 4.0 3.3 4 0 0 4 4 4 1 Tuftelin interacting protein N terminal G-patch PF01585.23 PSC72411.1 - 8.1e-14 51.2 6.2 8.1e-14 51.2 6.2 2.6 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 PSC72411.1 - 2.7e-06 27.4 5.3 2.7e-06 27.4 5.3 2.6 2 0 0 2 2 2 1 G-patch domain Myb_DNA-binding PF00249.31 PSC72411.1 - 7.3e-05 22.9 3.8 0.00011 22.4 0.8 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC72411.1 - 0.00032 20.9 0.1 0.0025 18.0 0.1 2.5 1 1 1 2 2 2 1 Myb-like DNA-binding domain RLL PF10036.9 PSC72411.1 - 0.0057 16.5 3.8 0.0057 16.5 3.8 2.3 3 0 0 3 3 3 1 RNA transcription, translation and transport factor protein Forkhead PF00250.18 PSC72411.1 - 0.027 14.7 0.0 0.084 13.1 0.0 1.9 1 1 0 1 1 1 0 Forkhead domain Glt_symporter PF03616.14 PSC72411.1 - 0.08 11.6 1.4 0.16 10.6 1.4 1.4 1 0 0 1 1 1 0 Sodium/glutamate symporter DDHD PF02862.17 PSC72411.1 - 1.4 9.1 6.9 1.7 8.7 1.4 2.8 3 0 0 3 3 3 0 DDHD domain CYTH PF01928.21 PSC72412.1 - 7.7e-22 78.1 0.1 9.3e-22 77.8 0.1 1.1 1 0 0 1 1 1 1 CYTH domain DUF4027 PF13219.6 PSC72412.1 - 0.099 12.5 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4027) DUF2344 PF10105.9 PSC72413.1 - 7.6e-30 104.0 0.0 1.7e-29 102.9 0.0 1.6 1 1 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2344) Radical_SAM PF04055.21 PSC72413.1 - 5.6e-14 52.9 0.0 1e-13 52.0 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily PDEase_I PF00233.19 PSC72414.1 - 2.1e-73 247.0 0.0 2.8e-73 246.6 0.0 1.1 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase HD PF01966.22 PSC72414.1 - 0.028 14.6 0.1 0.071 13.3 0.1 1.7 1 0 0 1 1 1 0 HD domain AbiEi_4 PF13338.6 PSC72414.1 - 0.14 12.3 0.2 0.14 12.3 0.2 3.1 3 0 0 3 3 3 0 Transcriptional regulator, AbiEi antitoxin OTCace PF00185.24 PSC72415.1 - 5.4e-53 179.3 0.1 7.9e-53 178.7 0.1 1.2 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain OTCace_N PF02729.21 PSC72415.1 - 2e-46 157.6 0.0 3e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain DUF1517 PF07466.11 PSC72416.1 - 1.8e-62 210.7 0.0 2.2e-62 210.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) DUF1517 PF07466.11 PSC72417.1 - 2.2e-62 210.4 0.0 2.8e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1517) G_glu_transpept PF01019.21 PSC72418.1 - 1.3e-12 47.3 4.8 3.3e-07 29.4 4.7 2.1 1 1 1 2 2 2 2 Gamma-glutamyltranspeptidase Ribonuclease_3 PF00636.26 PSC72418.1 - 2.6e-12 47.3 0.0 4.2e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease III domain UL17 PF17640.2 PSC72418.1 - 0.12 12.4 1.9 0.18 11.8 0.1 2.1 3 0 0 3 3 3 0 Uncharacterized UL17 Ribosomal_S20p PF01649.18 PSC72419.1 - 4e-21 75.4 8.1 6.2e-21 74.8 8.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S20 Haem_degrading PF03928.14 PSC72419.1 - 4.4 7.4 6.8 4 7.5 1.1 2.1 1 1 1 2 2 2 0 Haem-degrading Usp PF00582.26 PSC72420.1 - 1.3e-23 84.0 0.3 4.7e-23 82.3 0.3 1.7 1 1 0 1 1 1 1 Universal stress protein family DUF732 PF05305.14 PSC72420.1 - 0.089 13.2 0.1 0.15 12.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF732) PLU-1 PF08429.11 PSC72421.1 - 1.1e-68 231.9 6.1 1.1e-26 93.9 3.9 5.6 3 3 2 5 5 5 5 PLU-1-like protein JmjC PF02373.22 PSC72421.1 - 1.2e-39 135.2 0.5 2.6e-39 134.2 0.5 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase PHD PF00628.29 PSC72421.1 - 1.2e-19 69.9 57.4 8.5e-10 38.4 7.0 4.6 4 1 0 4 4 4 3 PHD-finger ARID PF01388.21 PSC72421.1 - 8.2e-15 55.3 0.0 2.4e-14 53.8 0.0 1.9 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain zf-C5HC2 PF02928.16 PSC72421.1 - 5e-11 42.8 18.1 5e-11 42.8 18.1 2.2 2 0 0 2 2 2 1 C5HC2 zinc finger JmjN PF02375.17 PSC72421.1 - 9.7e-11 41.5 0.0 2e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 jmjN domain GAGA PF09237.11 PSC72421.1 - 3.5 7.5 6.7 3.2 7.6 0.3 3.5 3 0 0 3 3 3 0 GAGA factor DUF2680 PF10925.8 PSC72423.1 - 0.64 10.1 4.3 17 5.5 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) MbeD_MobD PF04899.12 PSC72423.1 - 2.5 8.3 8.2 7.3 6.8 1.9 3.0 2 1 0 2 2 2 0 MbeD/MobD like DUF2680 PF10925.8 PSC72424.1 - 0.52 10.4 4.3 16 5.6 0.0 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2680) MbeD_MobD PF04899.12 PSC72424.1 - 1.6 8.9 7.8 6.7 6.9 2.0 3.0 2 1 0 2 2 2 0 MbeD/MobD like Usp PF00582.26 PSC72425.1 - 2.1e-42 144.9 13.9 2.4e-21 76.7 3.4 3.0 2 2 0 2 2 2 2 Universal stress protein family GARS_N PF02844.15 PSC72425.1 - 0.035 14.9 0.0 0.49 11.2 0.0 2.4 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, N domain Couple_hipA PF13657.6 PSC72425.1 - 0.047 14.3 0.0 10 6.8 0.0 2.4 2 0 0 2 2 2 0 HipA N-terminal domain Exo_endo_phos PF03372.23 PSC72426.1 - 1e-13 51.4 0.9 1.3e-13 51.1 0.0 1.6 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DDHD PF02862.17 PSC72426.1 - 0.045 13.9 0.6 4.6 7.3 0.0 2.2 2 0 0 2 2 2 0 DDHD domain IF-2B PF01008.17 PSC72427.1 - 9.2e-61 205.5 0.0 2.4e-60 204.2 0.0 1.6 1 1 0 1 1 1 1 Initiation factor 2 subunit family AIRC PF00731.20 PSC72428.1 - 1.3e-11 44.2 5.2 2.9e-11 43.2 5.2 1.6 1 0 0 1 1 1 1 AIR carboxylase FliG_M PF14841.6 PSC72428.1 - 0.043 14.0 0.2 0.36 11.1 0.2 2.4 2 0 0 2 2 2 0 FliG middle domain DUF1045 PF06299.12 PSC72428.1 - 0.078 13.0 0.2 0.16 11.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1045) FAD_binding_3 PF01494.19 PSC72429.1 - 6.5e-82 275.6 0.0 8.3e-82 275.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 PSC72429.1 - 0.0013 18.1 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PSC72429.1 - 0.0019 18.4 0.2 0.0019 18.4 0.2 3.4 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 PSC72429.1 - 0.0022 17.1 2.0 0.047 12.8 0.0 3.2 3 1 0 3 3 3 1 FAD binding domain DAO PF01266.24 PSC72429.1 - 0.016 14.8 0.0 0.016 14.8 0.0 3.0 3 1 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.17 PSC72429.1 - 0.039 13.2 0.7 0.084 12.1 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 PSC72429.1 - 0.059 12.6 0.2 0.13 11.5 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PSC72429.1 - 0.13 11.0 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 PSC72429.1 - 0.21 10.6 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 PSC72430.1 - 6.6e-82 275.6 0.0 8.3e-82 275.2 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.6 PSC72430.1 - 0.0013 18.1 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 PSC72430.1 - 0.0013 17.9 1.3 0.047 12.8 0.0 3.2 3 0 0 3 3 3 1 FAD binding domain NAD_binding_8 PF13450.6 PSC72430.1 - 0.0019 18.4 0.2 0.0019 18.4 0.2 3.3 4 0 0 4 4 4 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PSC72430.1 - 0.016 14.8 0.0 0.016 14.8 0.0 3.0 3 1 0 3 3 3 0 FAD dependent oxidoreductase Thi4 PF01946.17 PSC72430.1 - 0.039 13.2 0.7 0.084 12.1 0.1 1.8 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 PSC72430.1 - 0.059 12.6 0.2 0.13 11.5 0.2 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PSC72430.1 - 0.13 11.0 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein GIDA PF01134.22 PSC72430.1 - 0.21 10.6 0.0 0.32 10.0 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A PDZ_3 PF17815.1 PSC72431.1 - 1.2e-44 151.7 0.0 1.8e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 PSC72431.1 - 1.2e-22 81.5 0.3 1.2e-22 81.5 0.3 2.5 3 0 0 3 3 3 1 Trypsin-like peptidase domain Trypsin PF00089.26 PSC72431.1 - 6.5e-14 52.3 0.0 1.2e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 PSC72431.1 - 5.6e-08 33.0 0.0 7.9e-07 29.3 0.0 2.6 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 PSC72431.1 - 0.00022 20.0 0.3 0.00044 19.1 0.3 1.4 1 0 0 1 1 1 1 Peptidase S46 PDZ_6 PF17820.1 PSC72431.1 - 0.00048 19.9 0.1 0.15 11.9 0.1 2.8 2 0 0 2 2 2 2 PDZ domain PDZ_3 PF17815.1 PSC72432.1 - 1.2e-44 151.7 0.0 1.8e-44 151.1 0.0 1.3 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 PSC72432.1 - 1.2e-22 81.5 0.3 1.2e-22 81.5 0.3 2.5 3 0 0 3 3 3 1 Trypsin-like peptidase domain Trypsin PF00089.26 PSC72432.1 - 6.5e-14 52.3 0.0 1.2e-13 51.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 PSC72432.1 - 5.6e-08 33.0 0.0 7.9e-07 29.3 0.0 2.6 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 PSC72432.1 - 0.00024 19.9 0.3 0.00044 19.1 0.3 1.3 1 0 0 1 1 1 1 Peptidase S46 PDZ_6 PF17820.1 PSC72432.1 - 0.00048 19.9 0.1 0.15 11.9 0.1 2.8 2 0 0 2 2 2 2 PDZ domain Glyco_hydro_46 PF01374.18 PSC72433.1 - 1.6e-49 168.4 0.0 1.9e-49 168.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 46 Chitin_bind_1 PF00187.19 PSC72433.1 - 9.4e-08 32.4 16.3 9.4e-08 32.4 16.3 1.7 2 0 0 2 2 2 1 Chitin recognition protein BSD PF03909.17 PSC72434.1 - 5.9e-15 55.0 0.4 7.2e-11 41.9 0.6 2.5 2 0 0 2 2 2 2 BSD domain PH_TFIIH PF08567.11 PSC72434.1 - 0.02 15.2 0.0 0.044 14.1 0.0 1.6 1 0 0 1 1 1 0 TFIIH p62 subunit, N-terminal domain Trp_syntA PF00290.20 PSC72435.1 - 1.4e-91 306.0 0.1 1.7e-91 305.7 0.1 1.1 1 0 0 1 1 1 1 Tryptophan synthase alpha chain His_biosynth PF00977.21 PSC72435.1 - 0.00033 20.2 0.1 0.00064 19.2 0.1 1.5 1 0 0 1 1 1 1 Histidine biosynthesis protein Pterin_bind PF00809.22 PSC72435.1 - 0.00081 19.1 0.0 0.0028 17.4 0.0 1.9 1 1 0 1 1 1 1 Pterin binding enzyme Ribul_P_3_epim PF00834.19 PSC72435.1 - 0.00098 18.6 0.1 0.0032 16.9 0.1 1.9 2 0 0 2 2 2 1 Ribulose-phosphate 3 epimerase family Peripla_BP_1 PF00532.21 PSC72435.1 - 0.0031 17.0 0.1 3.6 6.9 0.1 3.1 3 0 0 3 3 3 1 Periplasmic binding proteins and sugar binding domain of LacI family PEP_mutase PF13714.6 PSC72435.1 - 0.0048 16.4 0.2 0.73 9.2 0.0 2.7 2 1 1 3 3 3 1 Phosphoenolpyruvate phosphomutase PcrB PF01884.17 PSC72435.1 - 0.0059 16.1 0.2 0.099 12.1 0.1 2.3 2 0 0 2 2 2 1 PcrB family NanE PF04131.14 PSC72435.1 - 0.0088 15.3 0.4 0.025 13.8 0.1 1.9 2 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase ALF PF03752.13 PSC72435.1 - 0.043 13.8 1.2 0.22 11.5 1.2 2.3 1 0 0 1 1 1 0 Short repeats of unknown function TMP-TENI PF02581.17 PSC72435.1 - 0.067 12.5 0.1 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 Thiamine monophosphate synthase Spore_YtrH PF14034.6 PSC72435.1 - 0.083 13.1 0.2 0.84 9.8 0.1 2.4 1 1 1 2 2 2 0 Sporulation protein YtrH PA PF02225.22 PSC72435.1 - 0.088 12.8 0.1 16 5.6 0.0 2.8 1 1 1 2 2 2 0 PA domain DUF1652 PF07865.11 PSC72435.1 - 0.13 12.1 0.3 7.7 6.4 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1652) rve PF00665.26 PSC72436.1 - 1.2e-18 67.4 0.0 2.6e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC72436.1 - 0.0092 15.7 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain MCM_lid PF17855.1 PSC72438.1 - 0.034 14.6 1.1 0.073 13.5 1.1 1.5 1 0 0 1 1 1 0 MCM AAA-lid domain Myb_CC_LHEQLE PF14379.6 PSC72439.1 - 2.3e-15 56.0 10.7 8.3e-15 54.2 10.7 2.0 1 0 0 1 1 1 1 MYB-CC type transfactor, LHEQLE motif Myb_DNA-binding PF00249.31 PSC72439.1 - 8.8e-08 32.2 0.0 1.6e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain K_channel_TID PF07941.11 PSC72439.1 - 0.017 15.5 1.9 0.017 15.5 1.9 8.9 8 4 1 9 9 9 0 Potassium channel Kv1.4 tandem inactivation domain DUF3464 PF11947.8 PSC72439.1 - 0.42 10.4 4.8 1 9.1 4.8 1.6 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CPSF100_C PF13299.6 PSC72439.1 - 0.92 9.7 5.0 5.9 7.0 2.5 2.4 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal TFIIA PF03153.13 PSC72439.1 - 0.93 9.4 47.9 3.5 7.5 38.2 2.5 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 PSC72439.1 - 4 7.0 27.4 0.55 9.8 22.8 1.9 2 0 0 2 2 2 0 Spt20 family Popeye PF04831.13 PSC72441.1 - 3.7e-06 27.1 0.0 4.9e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 Popeye protein conserved region cNMP_binding PF00027.29 PSC72441.1 - 0.00012 22.0 0.0 0.00023 21.2 0.0 1.4 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Caudo_TAP PF02413.17 PSC72442.1 - 0.036 14.2 0.5 0.074 13.2 0.5 1.5 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK CCDC85 PF10226.9 PSC72442.1 - 0.13 11.9 0.1 0.25 11.0 0.1 1.4 1 0 0 1 1 1 0 CCDC85 family Pkinase_Tyr PF07714.17 PSC72443.1 - 1.7e-43 148.8 0.0 2.4e-43 148.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC72443.1 - 1.4e-37 129.5 0.0 2.2e-37 128.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GAF PF01590.26 PSC72443.1 - 5.6e-05 23.8 0.2 0.00029 21.5 0.1 2.2 2 0 0 2 2 2 1 GAF domain Pkinase_fungal PF17667.1 PSC72443.1 - 0.11 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Nudix_hydro PF18290.1 PSC72444.1 - 2.5e-28 97.9 0.0 4.3e-28 97.1 0.0 1.4 1 0 0 1 1 1 1 Nudix hydrolase domain NUDIX PF00293.28 PSC72444.1 - 2.2e-22 79.5 0.9 4.1e-22 78.6 0.9 1.4 1 0 0 1 1 1 1 NUDIX domain Mut7-C PF01927.16 PSC72445.1 - 1e-28 100.3 0.0 1.7e-28 99.5 0.0 1.3 1 0 0 1 1 1 1 Mut7-C RNAse domain DNA_pol_A_exo1 PF01612.20 PSC72445.1 - 2.2e-10 40.5 0.0 3.8e-10 39.7 0.0 1.4 1 0 0 1 1 1 1 3'-5' exonuclease DUF5615 PF18480.1 PSC72445.1 - 0.076 12.8 0.0 0.17 11.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) Phage_30_3 PF08010.11 PSC72445.1 - 0.18 11.6 0.1 0.18 11.6 0.1 1.8 2 0 0 2 2 2 0 Bacteriophage protein GP30.3 Med15 PF09606.10 PSC72445.1 - 4.7 5.8 19.7 7.9 5.0 19.7 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Big_3_4 PF13754.6 PSC72446.1 - 0.038 13.7 0.0 0.083 12.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function Big_3_4 PF13754.6 PSC72447.1 - 0.037 13.8 0.0 0.08 12.7 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function Glycolytic PF00274.19 PSC72448.1 - 6.3e-141 469.1 0.0 1.1e-140 468.3 0.0 1.3 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I SBP PF03110.14 PSC72448.1 - 5.2e-24 84.3 2.2 9.6e-24 83.5 2.2 1.4 1 0 0 1 1 1 1 SBP domain Sugar_tr PF00083.24 PSC72448.1 - 6.6e-19 68.1 22.9 1.3e-18 67.2 22.9 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter Pyr_redox_2 PF07992.14 PSC72448.1 - 2.4e-10 40.1 0.2 6.5e-05 22.3 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PSC72448.1 - 1.4e-09 38.0 0.8 0.00015 21.4 0.4 2.6 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 PSC72448.1 - 3.6e-09 35.8 0.1 1.4e-05 24.0 0.2 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_3 PF01494.19 PSC72448.1 - 8e-09 35.2 0.3 2.2e-06 27.2 0.4 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 PSC72448.1 - 1.2e-06 27.9 0.6 1.2e-06 27.9 0.6 3.9 5 0 0 5 5 5 2 FAD binding domain MFS_1 PF07690.16 PSC72448.1 - 5.1e-06 25.7 36.4 5.1e-06 25.7 36.4 2.7 1 1 1 2 2 2 1 Major Facilitator Superfamily GIDA PF01134.22 PSC72448.1 - 9.1e-06 25.0 1.2 0.00051 19.2 0.1 3.0 3 0 0 3 3 3 1 Glucose inhibited division protein A FAD_oxidored PF12831.7 PSC72448.1 - 1.2e-05 24.9 0.5 0.00021 20.8 0.5 2.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 PSC72448.1 - 2.1e-05 24.7 0.1 0.00056 20.1 0.1 3.5 3 0 0 3 3 2 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 PSC72448.1 - 0.0003 21.3 0.2 0.54 10.9 0.2 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PSC72448.1 - 0.00091 18.6 0.1 0.002 17.4 0.1 1.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PSC72448.1 - 0.002 18.2 1.0 0.22 11.5 0.0 2.7 2 0 0 2 2 2 1 FAD-NAD(P)-binding Thi4 PF01946.17 PSC72448.1 - 0.0039 16.5 0.1 0.0085 15.4 0.1 1.5 1 0 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 PSC72448.1 - 0.0043 16.2 1.7 0.0081 15.3 0.3 2.0 2 0 0 2 2 2 1 Lycopene cyclase protein AlaDh_PNT_C PF01262.21 PSC72448.1 - 0.02 14.2 1.0 0.043 13.1 1.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ApbA PF02558.16 PSC72448.1 - 0.028 14.1 0.1 0.056 13.1 0.1 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Amino_oxidase PF01593.24 PSC72448.1 - 0.035 13.4 0.2 7.5 5.7 0.0 2.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase Myb_DNA-binding PF00249.31 PSC72449.1 - 8.3e-32 109.1 1.8 3.2e-15 56.1 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC72449.1 - 8.8e-26 89.9 0.1 8.6e-16 57.9 0.0 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 PSC72449.1 - 0.061 13.4 0.0 3.2 7.8 0.0 2.2 2 0 0 2 2 2 0 SLIDE Myb_DNA-bind_7 PF15963.5 PSC72449.1 - 0.21 11.5 0.0 1.5 8.8 0.0 2.0 1 1 0 2 2 2 0 Myb DNA-binding like Myb_DNA-binding PF00249.31 PSC72450.1 - 8.5e-32 109.1 1.8 3.2e-15 56.0 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC72450.1 - 9e-26 89.9 0.1 8.7e-16 57.9 0.0 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain SLIDE PF09111.10 PSC72450.1 - 0.062 13.3 0.0 3.2 7.8 0.0 2.2 2 0 0 2 2 2 0 SLIDE Myb_DNA-bind_7 PF15963.5 PSC72450.1 - 0.21 11.5 0.1 1.5 8.7 0.0 2.0 1 1 0 2 2 2 0 Myb DNA-binding like Pyr_redox_2 PF07992.14 PSC72451.1 - 1.2e-50 172.4 0.1 1.4e-50 172.2 0.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PSC72451.1 - 4.4e-23 82.0 0.0 3.1e-19 69.4 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PSC72451.1 - 2.1e-19 69.9 0.3 3.7e-18 65.8 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PSC72451.1 - 5.1e-07 29.1 0.7 0.021 13.9 0.4 4.0 4 0 0 4 4 4 2 Glucose inhibited division protein A HI0933_like PF03486.14 PSC72451.1 - 7.6e-07 28.2 2.1 0.047 12.4 0.3 4.1 3 1 1 4 4 4 2 HI0933-like protein FAD_binding_3 PF01494.19 PSC72451.1 - 3.8e-06 26.4 0.4 0.051 12.8 0.1 2.2 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.17 PSC72451.1 - 2e-05 24.0 0.3 0.0018 17.6 0.1 2.6 2 1 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 PSC72451.1 - 5.4e-05 23.3 0.2 0.22 11.8 0.1 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 PSC72451.1 - 6.7e-05 22.1 3.3 0.041 13.0 0.5 4.0 3 1 0 4 4 4 1 FAD binding domain FAD_oxidored PF12831.7 PSC72451.1 - 0.00018 21.0 0.2 0.00052 19.5 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 PSC72451.1 - 0.00091 19.6 0.1 0.047 14.1 0.0 2.5 2 1 0 2 2 2 1 Putative NAD(P)-binding DAO PF01266.24 PSC72451.1 - 0.0044 16.7 0.3 1.6 8.2 0.4 3.1 3 0 0 3 3 3 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 PSC72451.1 - 0.0047 16.2 0.8 0.56 9.5 0.1 2.3 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain F420_oxidored PF03807.17 PSC72451.1 - 0.012 16.1 0.2 0.28 11.8 0.0 2.5 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent K_oxygenase PF13434.6 PSC72451.1 - 0.016 14.4 0.0 0.052 12.7 0.0 1.8 2 1 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Shikimate_DH PF01488.20 PSC72451.1 - 0.051 13.6 0.0 2.6 8.1 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase Sin_N PF04801.13 PSC72452.1 - 2.7e-50 171.8 0.0 4.8e-50 171.0 0.0 1.4 1 0 0 1 1 1 1 Sin-like protein conserved region Cu-oxidase PF00394.22 PSC72452.1 - 2.5e-25 89.5 0.0 1.7e-24 86.8 0.0 2.2 2 0 0 2 2 2 1 Multicopper oxidase Cu-oxidase_2 PF07731.14 PSC72452.1 - 2e-21 76.2 0.2 1.6e-20 73.3 0.2 2.3 2 0 0 2 2 2 1 Multicopper oxidase Glyco_transf_90 PF05686.12 PSC72452.1 - 8.5e-14 51.3 0.0 4.1e-08 32.6 0.0 2.6 2 1 0 2 2 2 2 Glycosyl transferase family 90 Cu-oxidase_3 PF07732.15 PSC72452.1 - 1.9e-07 31.1 0.1 5.6e-06 26.4 0.1 2.4 2 0 0 2 2 2 1 Multicopper oxidase SR-25 PF10500.9 PSC72453.1 - 0.012 15.2 15.7 0.017 14.7 15.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RNA_polI_A34 PF08208.11 PSC72453.1 - 0.83 9.7 35.6 5.4 7.1 35.6 2.5 1 1 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Neur_chan_memb PF02932.16 PSC72453.1 - 5.1 7.1 4.4 6.4 6.8 4.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2722 PF10846.8 PSC72454.1 - 0.0035 16.4 4.9 0.0035 16.4 4.9 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) FAA_hydro_N_2 PF18288.1 PSC72454.1 - 0.061 13.8 0.8 0.061 13.8 0.8 3.6 4 1 0 4 4 4 0 Fumarylacetoacetase N-terminal domain 2 Put_DNA-bind_N PF06971.13 PSC72454.1 - 0.1 12.6 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus DUF4778 PF16008.5 PSC72454.1 - 8.5 6.3 8.6 0.97 9.4 0.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4778) Glyco_hydro_9 PF00759.19 PSC72455.1 - 2.8e-98 330.1 9.9 3.3e-98 329.8 9.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 MATH PF00917.26 PSC72457.1 - 6.7e-23 81.0 0.0 1.1e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 MATH domain GST_C_3 PF14497.6 PSC72458.1 - 1.6e-15 57.1 0.0 3.1e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PSC72458.1 - 7.6e-10 38.9 0.1 4.2e-09 36.5 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PSC72458.1 - 1.9e-07 31.3 0.0 1e-06 29.0 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain ATG16 PF08614.11 PSC72458.1 - 0.013 15.7 5.9 0.013 15.7 5.9 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GST_N_3 PF13417.6 PSC72458.1 - 0.16 12.4 0.0 0.58 10.6 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF4509 PF14970.6 PSC72458.1 - 0.39 10.6 3.9 0.64 9.9 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) Tropomyosin_1 PF12718.7 PSC72458.1 - 1.1 9.4 16.1 0.35 11.0 10.6 2.2 1 1 2 3 3 3 0 Tropomyosin like Tup_N PF08581.10 PSC72458.1 - 1.2 9.5 6.7 0.35 11.2 3.4 1.9 2 0 0 2 2 2 0 Tup N-terminal Macoilin PF09726.9 PSC72458.1 - 5.7 5.4 11.9 9.2 4.7 11.9 1.2 1 0 0 1 1 1 0 Macoilin family YabA PF06156.13 PSC72458.1 - 7.6 7.2 6.7 2 9.1 1.4 2.5 2 1 1 3 3 3 0 Initiation control protein YabA DUF3584 PF12128.8 PSC72458.1 - 8.6 3.7 28.2 12 3.3 28.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Leu_zip PF15294.6 PSC72458.1 - 9.8 5.6 11.3 10 5.6 7.6 1.9 1 1 1 2 2 2 0 Leucine zipper GST_C_3 PF14497.6 PSC72459.1 - 1.6e-15 57.1 0.0 3.1e-15 56.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PSC72459.1 - 7.6e-10 38.9 0.1 4.2e-09 36.5 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 PSC72459.1 - 1.9e-07 31.3 0.0 1e-06 29.0 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain ATG16 PF08614.11 PSC72459.1 - 0.013 15.7 5.9 0.013 15.7 5.9 2.4 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) GST_N_3 PF13417.6 PSC72459.1 - 0.16 12.4 0.0 0.58 10.6 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF4509 PF14970.6 PSC72459.1 - 0.39 10.6 3.9 0.64 9.9 3.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) Tropomyosin_1 PF12718.7 PSC72459.1 - 1.1 9.4 16.1 0.35 11.0 10.6 2.2 1 1 2 3 3 3 0 Tropomyosin like Tup_N PF08581.10 PSC72459.1 - 1.2 9.5 6.7 0.35 11.2 3.4 1.9 2 0 0 2 2 2 0 Tup N-terminal Macoilin PF09726.9 PSC72459.1 - 5.7 5.4 11.9 9.2 4.7 11.9 1.2 1 0 0 1 1 1 0 Macoilin family YabA PF06156.13 PSC72459.1 - 7.6 7.2 6.7 2 9.1 1.4 2.5 2 1 1 3 3 3 0 Initiation control protein YabA DUF3584 PF12128.8 PSC72459.1 - 8.6 3.7 28.2 12 3.3 28.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Leu_zip PF15294.6 PSC72459.1 - 9.8 5.6 11.3 10 5.6 7.6 1.9 1 1 1 2 2 2 0 Leucine zipper Acetate_kinase PF00871.17 PSC72460.1 - 5.5e-135 450.0 0.0 7.6e-135 449.6 0.0 1.2 1 0 0 1 1 1 1 Acetokinase family Citrate_synt PF00285.21 PSC72460.1 - 1e-105 353.8 0.0 5.4e-105 351.4 0.0 1.9 2 0 0 2 2 2 1 Citrate synthase, C-terminal domain Pkinase PF00069.25 PSC72461.1 - 3.1e-65 220.2 0.0 5.7e-65 219.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain EF-hand_6 PF13405.6 PSC72461.1 - 1.5e-28 96.3 6.9 4.7e-05 23.0 0.1 7.5 8 0 0 8 8 7 4 EF-hand domain EF-hand_7 PF13499.6 PSC72461.1 - 1.1e-27 96.3 3.7 2.9e-10 40.5 0.0 5.5 5 1 0 5 5 5 4 EF-hand domain pair Pkinase_Tyr PF07714.17 PSC72461.1 - 2.3e-26 92.7 0.0 3.6e-26 92.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_1 PF00036.32 PSC72461.1 - 1.6e-25 86.7 2.0 0.00019 20.7 0.1 7.7 8 0 0 8 8 8 5 EF hand EF-hand_8 PF13833.6 PSC72461.1 - 2.2e-21 75.5 7.4 7.9e-05 22.4 0.0 7.1 4 2 3 7 7 7 4 EF-hand domain pair EF-hand_5 PF13202.6 PSC72461.1 - 3.8e-12 45.1 6.9 0.037 13.5 0.2 6.0 7 0 0 7 7 7 3 EF hand EF-hand_9 PF14658.6 PSC72461.1 - 1e-11 45.0 0.3 0.00087 19.6 0.0 4.7 4 1 1 5 5 5 2 EF-hand domain EF-hand_14 PF17959.1 PSC72461.1 - 8.4e-05 22.8 0.4 11 6.4 0.0 4.6 5 0 0 5 5 4 0 EF-hand domain Kinase-like PF14531.6 PSC72461.1 - 0.00058 19.3 0.2 0.003 16.9 0.2 2.0 1 1 0 1 1 1 1 Kinase-like Caleosin PF05042.13 PSC72461.1 - 0.001 19.0 0.1 1.1 9.2 0.0 3.7 4 0 0 4 4 4 1 Caleosin related protein Sterol_MT_C PF08498.10 PSC72461.1 - 0.047 14.0 0.0 2.3 8.6 0.1 3.1 3 0 0 3 3 3 0 Sterol methyltransferase C-terminal Kdo PF06293.14 PSC72461.1 - 0.062 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family GPHH PF16905.5 PSC72461.1 - 0.16 11.8 0.0 8.2 6.3 0.0 3.0 3 0 0 3 3 3 0 Voltage-dependent L-type calcium channel, IQ-associated Toprim_2 PF13155.6 PSC72461.1 - 0.18 12.2 4.0 51 4.4 0.0 3.9 3 1 1 4 4 4 0 Toprim-like p25-alpha PF05517.12 PSC72461.1 - 0.24 11.6 0.0 6.6 6.9 0.0 2.7 3 0 0 3 3 3 0 p25-alpha DUF3349 PF11829.8 PSC72461.1 - 0.52 11.1 3.9 96 3.9 0.0 4.1 2 1 1 4 4 4 0 Protein of unknown function (DUF3349) DSBA PF01323.20 PSC72461.1 - 2.3 8.0 9.6 0.077 12.8 0.9 2.4 2 1 0 3 3 3 0 DSBA-like thioredoxin domain tRNA-synt_1 PF00133.22 PSC72462.1 - 1.7e-207 690.5 0.0 9.4e-207 688.0 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PSC72462.1 - 1.9e-36 125.3 1.2 2.4e-36 125.0 0.0 1.8 2 0 0 2 2 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 PSC72462.1 - 1.9e-14 53.2 0.2 2.5e-07 29.8 0.0 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 PSC72462.1 - 3.5e-09 36.5 0.0 1.4e-07 31.2 0.0 2.3 1 1 1 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.9 PSC72462.1 - 5.9e-05 23.3 4.1 5.9e-05 23.3 4.1 2.4 2 0 0 2 2 1 1 Valyl tRNA synthetase tRNA binding arm GST_C_2 PF13410.6 PSC72462.1 - 7.9e-05 22.6 3.8 0.00035 20.5 3.8 2.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain HEAT_2 PF13646.6 PSC72462.1 - 0.00031 21.1 8.7 0.00031 21.1 8.7 6.0 5 0 0 5 5 5 2 HEAT repeats tRNA-synt_1e PF01406.19 PSC72462.1 - 0.00043 19.7 0.0 0.31 10.3 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Vac14_Fab1_bd PF12755.7 PSC72462.1 - 0.0041 17.7 0.0 8.3 7.1 0.0 4.0 4 0 0 4 4 3 1 Vacuolar 14 Fab1-binding region GST_N PF02798.20 PSC72462.1 - 0.056 13.8 0.0 0.37 11.2 0.0 2.5 2 1 0 2 2 1 0 Glutathione S-transferase, N-terminal domain HEAT PF02985.22 PSC72462.1 - 0.1 12.9 29.1 0.26 11.6 0.2 8.1 9 0 0 9 9 9 0 HEAT repeat DUF4632 PF15451.6 PSC72462.1 - 4.9 7.3 8.4 0.79 9.8 0.1 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4632) MGDG_synth PF06925.11 PSC72463.1 - 3.5e-36 124.9 0.0 5.1e-36 124.3 0.0 1.2 1 0 0 1 1 1 1 Monogalactosyldiacylglycerol (MGDG) synthase Glyco_tran_28_C PF04101.16 PSC72463.1 - 1.6e-11 44.5 0.0 1.6e-11 44.5 0.0 2.2 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain Acetyltransf_1 PF00583.25 PSC72463.1 - 1.9e-08 34.6 0.5 3.9e-08 33.5 0.5 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PSC72463.1 - 9.5e-06 25.6 0.0 2.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PSC72463.1 - 1.8e-05 25.1 0.3 3.8e-05 24.0 0.3 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_trans_1_4 PF13692.6 PSC72463.1 - 2.3e-05 24.8 0.1 7.6e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Acetyltransf_CG PF14542.6 PSC72463.1 - 0.16 12.1 0.8 0.34 11.1 0.0 1.9 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Glyco_transf_4 PF13439.6 PSC72463.1 - 0.66 10.0 3.4 0.98 9.4 1.1 2.5 2 1 0 2 2 2 0 Glycosyltransferase Family 4 TFIIA PF03153.13 PSC72463.1 - 6.3 6.7 18.8 0.93 9.4 12.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 PSC72463.1 - 9 5.1 6.4 16 4.3 6.4 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ribosomal_L28 PF00830.19 PSC72464.1 - 8e-19 67.6 4.3 1.8e-18 66.4 4.3 1.7 1 0 0 1 1 1 1 Ribosomal L28 family RRM_1 PF00076.22 PSC72464.1 - 1.4e-18 66.5 0.0 2.8e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MPS2 PF17060.5 PSC72464.1 - 0.021 14.1 1.2 0.033 13.5 1.2 1.2 1 0 0 1 1 1 0 Monopolar spindle protein 2 DUF4407 PF14362.6 PSC72464.1 - 0.073 12.4 7.8 2.7 7.3 10.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) Atg14 PF10186.9 PSC72464.1 - 0.36 9.9 3.2 0.64 9.0 3.2 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADIP PF11559.8 PSC72464.1 - 0.4 10.8 4.4 0.58 10.2 3.6 1.6 1 1 0 1 1 1 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.8 PSC72464.1 - 0.4 10.7 2.9 0.94 9.5 2.9 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding FAM76 PF16046.5 PSC72464.1 - 2.1 7.6 6.1 0.38 10.1 0.4 2.0 2 0 0 2 2 2 0 FAM76 protein Spc7 PF08317.11 PSC72464.1 - 2.5 6.9 5.3 5.1 5.9 5.1 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein Telomere_Sde2_2 PF13297.6 PSC72465.1 - 2.3e-23 81.6 0.7 5.1e-23 80.5 0.7 1.6 1 0 0 1 1 1 1 Telomere stability C-terminal Sde2_N_Ubi PF13019.6 PSC72465.1 - 3.9e-22 78.8 2.6 8e-22 77.8 2.6 1.6 1 0 0 1 1 1 1 Silencing defective 2 N-terminal ubiquitin domain ubiquitin PF00240.23 PSC72465.1 - 3.9e-19 68.2 0.0 8e-19 67.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PSC72465.1 - 2e-08 33.9 0.0 4.1e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DNApol_Exo PF18136.1 PSC72465.1 - 0.014 14.6 0.9 0.032 13.4 0.9 1.5 1 0 0 1 1 1 0 DNA mitochondrial polymerase exonuclease domain FemAB PF02388.16 PSC72465.1 - 0.12 11.2 5.3 0.19 10.6 5.3 1.2 1 0 0 1 1 1 0 FemAB family Pex14_N PF04695.13 PSC72465.1 - 3.6 8.2 15.4 27 5.4 0.2 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region tRNA-synt_1c PF00749.21 PSC72466.1 - 6.9e-111 370.1 0.1 1.2e-110 369.3 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain Cyclin_N PF00134.23 PSC72466.1 - 3.5e-47 159.3 1.3 3.5e-47 159.3 1.3 2.4 4 0 0 4 4 4 1 Cyclin, N-terminal domain tRNA_synt_1c_R1 PF04558.15 PSC72466.1 - 7.1e-46 156.2 0.1 1.6e-45 155.0 0.1 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA-synt_1c_C PF03950.18 PSC72466.1 - 5.8e-39 133.7 0.0 2.7e-38 131.6 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain Cyclin_C PF02984.19 PSC72466.1 - 5e-26 91.1 1.7 9.7e-26 90.2 1.7 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain tRNA_synt_1c_R2 PF04557.15 PSC72466.1 - 1.2e-13 51.7 0.9 3.5e-13 50.3 0.9 1.8 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 TauD PF02668.16 PSC72467.1 - 4.7e-30 105.3 0.0 6.3e-30 104.9 0.0 1.1 1 0 0 1 1 1 1 Taurine catabolism dioxygenase TauD, TfdA family Cu-oxidase_2 PF07731.14 PSC72468.1 - 1.4e-39 134.9 3.8 8.6e-36 122.7 0.7 3.5 3 0 0 3 3 3 3 Multicopper oxidase Cu-oxidase PF00394.22 PSC72468.1 - 7.2e-27 94.5 0.0 1.3e-25 90.3 0.0 2.6 3 0 0 3 3 3 1 Multicopper oxidase Cu-oxidase_3 PF07732.15 PSC72468.1 - 1.2e-12 47.9 10.7 5.5e-11 42.5 0.7 4.3 4 0 0 4 4 4 2 Multicopper oxidase Exo_endo_phos PF03372.23 PSC72469.1 - 4.9e-11 42.6 0.4 6.7e-11 42.2 0.4 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Aa_trans PF01490.18 PSC72470.1 - 5.8e-26 91.1 9.9 7.6e-26 90.8 9.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein FoP_duplication PF13865.6 PSC72470.1 - 1.2e-15 57.8 19.7 1.2e-15 57.8 19.7 2.3 1 1 1 2 2 2 1 C-terminal duplication domain of Friend of PRMT1 SpoIIIAC PF06686.11 PSC72470.1 - 3.7 7.8 6.3 17 5.7 0.1 3.1 3 0 0 3 3 3 0 Stage III sporulation protein AC/AD protein family Ribosomal_60s PF00428.19 PSC72470.1 - 4.8 7.8 16.5 10 6.8 16.5 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein PPR_2 PF13041.6 PSC72471.1 - 1.5e-44 149.9 2.4 2e-08 34.3 0.0 10.7 5 3 6 11 11 11 8 PPR repeat family PPR PF01535.20 PSC72471.1 - 1.7e-39 131.3 6.1 3.3e-05 23.8 0.0 10.0 10 0 0 10 10 10 9 PPR repeat PPR_3 PF13812.6 PSC72471.1 - 1.6e-37 127.4 0.0 2e-05 24.6 0.0 7.9 5 3 3 8 8 8 7 Pentatricopeptide repeat domain PPR_long PF17177.4 PSC72471.1 - 3.6e-33 114.7 8.8 5.4e-12 45.5 0.1 5.9 2 1 3 6 6 6 4 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 PSC72471.1 - 2.5e-28 97.5 3.7 0.00015 21.4 0.0 8.9 9 0 0 9 9 9 7 PPR repeat BTAD PF03704.17 PSC72471.1 - 0.029 14.8 19.1 0.13 12.7 4.9 5.5 3 1 2 5 5 5 0 Bacterial transcriptional activator domain Sugar_tr PF00083.24 PSC72472.1 - 8.5e-31 107.3 0.1 1.7e-28 99.7 0.0 2.6 2 1 0 3 3 3 2 Sugar (and other) transporter RRM_1 PF00076.22 PSC72472.1 - 6.7e-15 54.7 0.0 1.2e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MFS_1 PF07690.16 PSC72472.1 - 7.5e-05 21.8 5.1 7.5e-05 21.8 5.1 2.4 2 1 1 3 3 3 1 Major Facilitator Superfamily RL PF17797.1 PSC72472.1 - 0.032 14.2 0.2 0.065 13.2 0.2 1.5 1 0 0 1 1 1 0 RL domain RRM_7 PF16367.5 PSC72472.1 - 0.035 14.2 0.0 0.069 13.3 0.0 1.5 1 0 0 1 1 1 0 RNA recognition motif Myb_DNA-bind_6 PF13921.6 PSC72473.1 - 3.6e-11 43.2 1.5 7e-05 23.0 0.0 2.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 PSC72473.1 - 6.5e-08 32.7 6.9 0.0028 17.8 0.2 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 PSC72473.1 - 0.088 13.2 5.0 1.9 8.9 0.2 3.4 3 0 0 3 3 3 0 Myb/SANT-like DNA-binding domain POTRA_2 PF08479.11 PSC72474.1 - 0.16 11.8 0.0 0.42 10.5 0.0 1.7 1 0 0 1 1 1 0 POTRA domain, ShlB-type Rubis-subs-bind PF09273.11 PSC72475.1 - 1.4e-08 35.5 2.8 0.00013 22.7 0.1 2.5 2 0 0 2 2 2 2 Rubisco LSMT substrate-binding SET PF00856.28 PSC72475.1 - 1.5e-07 31.9 0.0 4e-07 30.6 0.0 1.7 1 1 0 1 1 1 1 SET domain PsbP PF01789.16 PSC72476.1 - 1.2e-32 113.2 0.5 2e-32 112.5 0.5 1.3 1 0 0 1 1 1 1 PsbP Rhodanese PF00581.20 PSC72476.1 - 9e-05 23.0 0.0 0.00017 22.1 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Sigma70_r1_2 PF00140.20 PSC72476.1 - 0.026 14.6 12.0 3.5 7.7 0.1 4.2 4 0 0 4 4 4 0 Sigma-70 factor, region 1.2 PsbP PF01789.16 PSC72477.1 - 1.2e-32 113.2 0.5 2e-32 112.5 0.5 1.3 1 0 0 1 1 1 1 PsbP Rhodanese PF00581.20 PSC72477.1 - 9.1e-05 22.9 0.0 0.00017 22.0 0.0 1.5 1 0 0 1 1 1 1 Rhodanese-like domain Sigma70_r1_2 PF00140.20 PSC72477.1 - 0.026 14.5 12.0 3.5 7.7 0.1 4.2 4 0 0 4 4 4 0 Sigma-70 factor, region 1.2 DUF1802 PF08819.11 PSC72478.1 - 5.1e-41 140.4 0.0 1.7e-40 138.7 0.0 1.9 2 1 0 2 2 2 1 Domain of unknown function (DUF1802) TrmO PF01980.16 PSC72478.1 - 3.9e-40 136.8 0.0 8e-40 135.8 0.0 1.6 1 0 0 1 1 1 1 tRNA-methyltransferase O Bax1-I PF01027.20 PSC72482.1 - 7.3e-29 101.1 17.5 8.6e-29 100.8 17.5 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF5480 PF17576.2 PSC72482.1 - 3.6 7.6 4.8 1.4 8.9 0.1 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5480) PTH2 PF01981.16 PSC72483.1 - 2.1e-42 144.1 0.1 2.6e-42 143.8 0.1 1.1 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 ABC_tran PF00005.27 PSC72484.1 - 8.8e-48 162.3 4.8 2.4e-22 79.9 0.0 4.3 4 0 0 4 4 4 2 ABC transporter AAA_21 PF13304.6 PSC72484.1 - 1.6e-18 67.5 8.6 0.00011 22.1 0.1 4.8 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PSC72484.1 - 3.4e-11 43.0 1.9 0.041 13.3 0.0 4.6 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PSC72484.1 - 1.1e-07 31.5 0.4 0.0035 17.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 PSC72484.1 - 6.2e-07 29.5 0.0 0.0023 18.0 0.0 3.4 3 0 0 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PSC72484.1 - 7.1e-07 29.3 0.1 0.0021 18.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 PSC72484.1 - 3.3e-06 27.4 2.5 0.049 13.9 0.0 3.3 4 0 0 4 4 2 2 AAA domain NACHT PF05729.12 PSC72484.1 - 4e-06 26.8 0.0 0.017 15.1 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.6 PSC72484.1 - 5.8e-06 26.1 0.5 0.0024 17.6 0.0 3.3 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 PSC72484.1 - 1.6e-05 25.4 2.2 0.2 12.0 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.22 PSC72484.1 - 2.5e-05 24.6 0.0 0.031 14.6 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 PSC72484.1 - 2.7e-05 24.7 0.4 2 9.0 0.0 4.1 3 0 0 3 3 3 1 AAA domain AAA PF00004.29 PSC72484.1 - 6.9e-05 23.3 0.0 1.4 9.3 0.0 3.6 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 PSC72484.1 - 9.9e-05 22.9 0.0 0.0023 18.5 0.0 5.4 6 0 0 6 6 4 2 AAA domain ABC_tran_Xtn PF12848.7 PSC72484.1 - 0.00021 21.3 8.9 0.00021 21.3 8.9 4.8 5 0 0 5 5 3 2 ABC transporter AAA_22 PF13401.6 PSC72484.1 - 0.00035 20.8 0.0 0.45 10.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 PSC72484.1 - 0.00069 19.2 3.3 0.054 13.1 0.2 3.9 3 2 0 3 3 2 1 AAA domain Mg_chelatase PF01078.21 PSC72484.1 - 0.00083 18.8 0.4 8.1 5.8 0.0 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 PSC72484.1 - 0.00094 19.0 0.0 0.63 9.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 PSC72484.1 - 0.0011 19.1 1.5 1.3 9.2 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 PSC72484.1 - 0.0042 17.1 0.0 4.2 7.4 0.0 3.2 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 PSC72484.1 - 0.005 16.8 0.0 1.2 9.0 0.0 2.8 3 0 0 3 3 2 1 Rad17 P-loop domain cobW PF02492.19 PSC72484.1 - 0.01 15.4 0.1 5.7 6.5 0.0 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 PSC72484.1 - 0.014 15.4 0.2 6.8 6.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 PSC72484.1 - 0.02 14.1 0.0 7.3 5.7 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 PSC72484.1 - 0.029 13.9 0.4 3.3 7.2 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 PSC72484.1 - 0.079 12.6 0.0 4 7.0 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain RuvB_N PF05496.12 PSC72484.1 - 0.1 12.4 1.8 30 4.3 0.1 3.5 2 1 1 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_15 PF13175.6 PSC72484.1 - 0.12 12.0 20.4 0.59 9.8 0.2 4.8 5 0 0 5 5 5 0 AAA ATPase domain AAA_27 PF13514.6 PSC72484.1 - 0.27 10.8 4.5 2.2 7.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain MukB PF04310.12 PSC72484.1 - 0.33 10.7 2.3 18 5.1 0.1 3.1 3 0 0 3 3 3 0 MukB N-terminal Dynamin_N PF00350.23 PSC72484.1 - 0.37 10.8 0.0 0.37 10.8 0.0 4.9 6 0 0 6 6 5 0 Dynamin family Adeno_IVa2 PF02456.15 PSC72484.1 - 0.55 9.0 1.6 16 4.2 0.0 2.9 3 0 0 3 3 3 0 Adenovirus IVa2 protein SbcCD_C PF13558.6 PSC72484.1 - 0.7 10.2 3.4 4.4 7.6 0.2 3.8 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Cytidylate_kin PF02224.18 PSC72484.1 - 0.75 9.5 7.5 1.3 8.7 0.0 3.1 3 0 0 3 3 2 0 Cytidylate kinase ABC_tran PF00005.27 PSC72485.1 - 8.5e-48 162.3 4.8 2.4e-22 79.9 0.0 4.3 4 0 0 4 4 4 2 ABC transporter AAA_21 PF13304.6 PSC72485.1 - 1.7e-18 67.4 9.4 0.00011 22.1 0.1 4.9 4 1 1 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PSC72485.1 - 3.4e-11 43.0 1.9 0.041 13.3 0.0 4.6 3 1 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PSC72485.1 - 1.1e-07 31.5 0.4 0.0035 17.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 PSC72485.1 - 3.1e-07 30.5 0.0 0.0023 18.0 0.0 3.6 3 0 0 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PSC72485.1 - 7e-07 29.3 0.1 0.0021 18.0 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_28 PF13521.6 PSC72485.1 - 3.3e-06 27.5 2.5 0.049 13.9 0.0 3.3 4 0 0 4 4 2 2 AAA domain NACHT PF05729.12 PSC72485.1 - 4e-06 26.8 0.0 0.017 15.1 0.0 2.4 2 0 0 2 2 2 2 NACHT domain AAA_30 PF13604.6 PSC72485.1 - 5.8e-06 26.2 0.5 0.0024 17.6 0.0 3.4 3 1 0 3 3 3 1 AAA domain AAA_16 PF13191.6 PSC72485.1 - 1.5e-05 25.4 2.2 0.2 12.0 0.0 3.1 3 0 0 3 3 3 2 AAA ATPase domain RNA_helicase PF00910.22 PSC72485.1 - 2.5e-05 24.6 0.0 0.031 14.6 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 PSC72485.1 - 6.9e-05 23.3 0.0 1.4 9.3 0.0 3.6 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 PSC72485.1 - 9.9e-05 22.9 0.0 0.0023 18.5 0.0 5.4 6 0 0 6 6 4 2 AAA domain ABC_tran_Xtn PF12848.7 PSC72485.1 - 0.00021 21.3 8.9 0.00021 21.3 8.9 4.9 5 0 0 5 5 3 2 ABC transporter AAA_22 PF13401.6 PSC72485.1 - 0.00035 20.9 0.0 0.45 10.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 PSC72485.1 - 0.00069 19.2 3.3 0.054 13.1 0.2 3.9 3 2 0 3 3 2 1 AAA domain Mg_chelatase PF01078.21 PSC72485.1 - 0.00083 18.8 0.4 8.1 5.8 0.0 3.3 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 PSC72485.1 - 0.00089 19.0 0.0 0.63 9.7 0.0 3.5 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 PSC72485.1 - 0.0011 19.1 1.5 1.3 9.2 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_14 PF13173.6 PSC72485.1 - 0.0042 17.1 0.0 4.2 7.4 0.0 3.2 3 0 0 3 3 2 1 AAA domain Rad17 PF03215.15 PSC72485.1 - 0.0049 16.8 0.0 1.2 9.0 0.0 2.8 3 0 0 3 3 2 1 Rad17 P-loop domain cobW PF02492.19 PSC72485.1 - 0.01 15.4 0.1 5.7 6.5 0.0 2.6 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 PSC72485.1 - 0.013 15.5 0.2 6.7 6.7 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 PSC72485.1 - 0.018 15.6 9.7 2 9.0 0.0 4.2 4 0 0 4 4 3 0 AAA domain NB-ARC PF00931.22 PSC72485.1 - 0.02 14.1 0.0 7.3 5.7 0.0 2.5 2 0 0 2 2 2 0 NB-ARC domain AAA_7 PF12775.7 PSC72485.1 - 0.028 13.9 0.4 3.3 7.2 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region ATP-synt_ab PF00006.25 PSC72485.1 - 0.079 12.6 0.0 4 7.0 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_15 PF13175.6 PSC72485.1 - 0.087 12.5 21.4 0.59 9.8 0.2 4.8 5 0 0 5 5 5 0 AAA ATPase domain RuvB_N PF05496.12 PSC72485.1 - 0.1 12.4 1.8 30 4.3 0.1 3.5 2 1 1 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain Dynamin_N PF00350.23 PSC72485.1 - 0.21 11.7 15.7 0.37 10.8 0.0 4.9 6 0 0 6 6 5 0 Dynamin family AAA_27 PF13514.6 PSC72485.1 - 0.25 10.9 4.5 2.2 7.8 0.0 3.2 3 0 0 3 3 3 0 AAA domain MukB PF04310.12 PSC72485.1 - 0.33 10.7 2.3 18 5.1 0.1 3.1 3 0 0 3 3 3 0 MukB N-terminal Adeno_IVa2 PF02456.15 PSC72485.1 - 0.54 9.0 1.6 16 4.2 0.0 2.9 3 0 0 3 3 3 0 Adenovirus IVa2 protein SbcCD_C PF13558.6 PSC72485.1 - 0.73 10.1 3.4 4.4 7.6 0.2 3.8 3 2 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Cytidylate_kin PF02224.18 PSC72485.1 - 0.75 9.5 7.5 1.3 8.7 0.0 3.1 3 0 0 3 3 2 0 Cytidylate kinase NUC153 PF08159.12 PSC72487.1 - 2.5e-13 49.6 0.4 4.9e-13 48.6 0.4 1.5 1 0 0 1 1 1 1 NUC153 domain ANAPC4_WD40 PF12894.7 PSC72487.1 - 0.011 16.0 0.0 0.064 13.6 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Herpeto_peptide PF14409.6 PSC72487.1 - 0.14 12.4 0.1 0.33 11.2 0.1 1.6 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Herpetosiphon NUMOD3 PF07460.11 PSC72488.1 - 2.8e-06 27.5 0.2 0.00035 20.7 0.0 2.6 2 0 0 2 2 2 2 NUMOD3 motif (2 copies) Adeno_E3B PF03376.14 PSC72488.1 - 0.0047 17.1 0.0 0.0083 16.3 0.0 1.4 1 0 0 1 1 1 1 Adenovirus E3B protein TctC PF03401.14 PSC72488.1 - 0.034 13.2 0.6 0.08 12.0 0.6 1.6 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter family receptor CI-B14_5a PF07347.12 PSC72489.1 - 5.2e-05 23.0 0.7 7.8e-05 22.5 0.7 1.3 1 0 0 1 1 1 1 NADH:ubiquinone oxidoreductase subunit B14.5a (Complex I-B14.5a) Aminotran_1_2 PF00155.21 PSC72490.1 - 5.6e-86 289.0 0.0 6.3e-86 288.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Ribosomal_S17e PF00833.18 PSC72492.1 - 9.8e-63 209.5 1.7 1.1e-62 209.3 1.7 1.0 1 0 0 1 1 1 1 Ribosomal S17 EamA PF00892.20 PSC72493.1 - 9.7e-45 152.1 22.6 9.2e-23 80.9 6.3 2.4 2 0 0 2 2 2 2 EamA-like transporter family rRNA_methylase PF06962.12 PSC72493.1 - 1.5e-35 122.2 0.0 2.6e-35 121.4 0.0 1.4 1 0 0 1 1 1 1 Putative rRNA methylase LRR_8 PF13855.6 PSC72493.1 - 0.0008 19.1 6.5 0.084 12.6 0.3 4.0 2 1 1 3 3 3 2 Leucine rich repeat Methyltransf_25 PF13649.6 PSC72493.1 - 0.0011 19.6 1.1 0.0019 18.9 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC72493.1 - 0.0015 18.3 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain F-box PF00646.33 PSC72493.1 - 0.016 15.1 0.2 0.072 13.0 0.2 2.3 1 0 0 1 1 1 0 F-box domain Ubie_methyltran PF01209.18 PSC72493.1 - 0.13 11.6 0.0 0.43 9.9 0.0 1.7 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family Ribosomal_S5 PF00333.20 PSC72494.1 - 1.4e-22 79.4 0.2 2.9e-22 78.4 0.2 1.6 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 PSC72494.1 - 7.5e-18 63.8 0.0 1.4e-17 62.9 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain FAM176 PF14851.6 PSC72494.1 - 7.6 6.2 6.2 1.7 8.3 0.2 2.1 2 0 0 2 2 2 0 FAM176 family Ubiq_cyt_C_chap PF03981.12 PSC72498.1 - 5e-27 94.7 0.3 5e-27 94.7 0.3 1.6 2 0 0 2 2 2 1 Ubiquinol-cytochrome C chaperone Pyr_redox PF00070.27 PSC72498.1 - 0.1 13.2 0.0 0.2 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Actin PF00022.19 PSC72499.1 - 1.2e-54 185.6 0.0 3.1e-54 184.1 0.0 1.6 1 1 0 1 1 1 1 Actin TsaE PF02367.17 PSC72501.1 - 2.5e-10 40.4 0.0 4.8e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Acetyltransf_1 PF00583.25 PSC72501.1 - 1.2e-08 35.2 0.5 2.8e-08 34.0 0.5 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PSC72501.1 - 6.5e-06 26.1 0.0 1.5e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PSC72501.1 - 1.3e-05 25.6 0.3 2.7e-05 24.5 0.3 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain NACHT PF05729.12 PSC72501.1 - 0.087 12.7 0.1 0.32 10.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain Acetyltransf_CG PF14542.6 PSC72501.1 - 0.1 12.8 0.8 0.25 11.5 0.0 2.0 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase TFIIA PF03153.13 PSC72501.1 - 2.3 8.1 16.9 0.39 10.7 10.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Methyltransf_16 PF10294.9 PSC72502.1 - 1.5e-21 76.9 0.0 2.1e-21 76.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase PrmA PF06325.13 PSC72502.1 - 8.7e-05 22.0 0.0 0.00014 21.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 PSC72502.1 - 0.0015 18.4 0.0 0.0029 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PSC72502.1 - 0.019 14.5 0.0 0.042 13.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_11 PF08241.12 PSC72502.1 - 0.025 15.2 0.1 0.12 13.0 0.0 2.3 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_12 PF08242.12 PSC72502.1 - 0.053 14.3 0.0 0.13 13.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Eapp_C PF10238.9 PSC72503.1 - 3.2e-43 147.3 6.2 1.1e-42 145.7 5.9 1.9 2 1 0 2 2 2 1 E2F-associated phosphoprotein DUF2722 PF10846.8 PSC72503.1 - 0.3 10.0 10.9 0.42 9.5 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Pex14_N PF04695.13 PSC72503.1 - 0.4 11.3 8.5 0.62 10.7 8.5 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Cauli_VI PF01693.16 PSC72504.1 - 2.3e-12 47.0 0.4 5.7e-12 45.7 0.4 1.7 1 0 0 1 1 1 1 Caulimovirus viroplasmin Glyco_transf_4 PF13439.6 PSC72504.1 - 1.4e-09 38.2 1.4 3.4e-09 36.9 1.4 1.6 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 PSC72504.1 - 5.1e-07 30.2 0.0 1.2e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DnaJ PF00226.31 PSC72504.1 - 0.0016 18.5 0.1 0.0039 17.3 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Glycos_transf_1 PF00534.20 PSC72504.1 - 0.0048 16.5 0.0 0.0092 15.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 PSC72504.1 - 0.32 11.4 3.2 0.84 10.1 0.0 3.0 2 0 0 2 2 2 0 Glycosyl transferases group 1 SPRY PF00622.28 PSC72505.1 - 2.2e-21 76.2 0.1 3.2e-21 75.7 0.1 1.2 1 0 0 1 1 1 1 SPRY domain CLTH PF10607.9 PSC72505.1 - 1.7e-20 73.4 0.0 2.4e-20 73.0 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 PSC72505.1 - 0.15 12.1 0.0 0.32 11.0 0.0 1.6 1 0 0 1 1 1 0 LisH Pkinase_Tyr PF07714.17 PSC72506.1 - 3e-42 144.7 0.0 4.2e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC72506.1 - 7.4e-36 123.9 0.0 1.1e-35 123.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain AOX PF01786.17 PSC72506.1 - 2.5e-23 82.8 0.9 5e-23 81.8 0.9 1.5 1 0 0 1 1 1 1 Alternative oxidase Pkinase_fungal PF17667.1 PSC72506.1 - 0.0054 15.6 0.0 0.0086 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PSC72506.1 - 0.019 14.9 1.6 0.044 13.7 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_60s PF00428.19 PSC72506.1 - 0.067 13.8 5.1 0.26 11.9 5.1 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Pkinase_Tyr PF07714.17 PSC72507.1 - 3e-42 144.7 0.0 4.2e-42 144.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC72507.1 - 7.4e-36 123.9 0.0 1.1e-35 123.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain AOX PF01786.17 PSC72507.1 - 2.5e-23 82.8 0.9 5e-23 81.8 0.9 1.5 1 0 0 1 1 1 1 Alternative oxidase Pkinase_fungal PF17667.1 PSC72507.1 - 0.0054 15.6 0.0 0.0086 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PSC72507.1 - 0.019 14.9 1.6 0.044 13.7 0.0 2.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_60s PF00428.19 PSC72507.1 - 0.067 13.8 5.1 0.26 11.9 5.1 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Exostosin PF03016.15 PSC72508.1 - 1.3e-33 116.5 0.2 1.9e-33 115.9 0.2 1.3 1 0 0 1 1 1 1 Exostosin family Nup192 PF11894.8 PSC72508.1 - 7.2e-16 56.6 0.0 1.6e-06 25.7 0.0 4.2 4 0 0 4 4 4 4 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup188 PF10487.9 PSC72508.1 - 3.2e-09 35.3 0.0 3.1e-05 22.2 0.0 2.8 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 Exostosin PF03016.15 PSC72509.1 - 1.3e-33 116.5 0.2 1.9e-33 115.9 0.2 1.3 1 0 0 1 1 1 1 Exostosin family Nup192 PF11894.8 PSC72509.1 - 7.2e-16 56.6 0.0 1.6e-06 25.7 0.0 4.2 4 0 0 4 4 4 4 Nuclear pore complex scaffold, nucleoporins 186/192/205 Nup188 PF10487.9 PSC72509.1 - 3.2e-09 35.3 0.0 3e-05 22.2 0.0 2.8 2 1 0 2 2 2 2 Nucleoporin subcomplex protein binding to Pom34 Peptidase_S49 PF01343.18 PSC72510.1 - 2.3e-26 92.6 0.0 5.2e-26 91.4 0.0 1.5 2 0 0 2 2 2 1 Peptidase family S49 CLP_protease PF00574.23 PSC72510.1 - 0.00079 19.4 0.2 0.0027 17.6 0.2 1.8 2 0 0 2 2 2 1 Clp protease SAD_SRA PF02182.17 PSC72511.1 - 9.9e-51 171.5 0.1 2.3e-50 170.3 0.1 1.6 1 0 0 1 1 1 1 SAD/SRA domain zf-C3HC4 PF00097.25 PSC72511.1 - 1.1e-13 50.7 23.8 4.6e-07 29.6 13.4 2.8 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC72511.1 - 4.7e-13 48.9 17.2 2.2e-07 30.7 0.3 2.7 2 0 0 2 2 2 2 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PSC72511.1 - 1.8e-10 40.5 30.5 1.8e-06 27.7 13.8 3.0 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PSC72511.1 - 3.8e-10 39.7 22.8 4.9e-05 23.4 12.4 2.7 2 0 0 2 2 2 2 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 PSC72511.1 - 6.5e-09 35.5 27.7 7e-07 29.0 10.6 3.3 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC72511.1 - 5.4e-08 32.7 24.1 0.0011 18.9 2.3 2.8 2 1 0 2 2 2 2 zinc-RING finger domain zf-RING_2 PF13639.6 PSC72511.1 - 6.9e-08 32.7 26.0 5e-05 23.5 11.9 2.9 2 1 0 2 2 2 2 Ring finger domain Prok-RING_4 PF14447.6 PSC72511.1 - 5.8e-05 22.9 28.9 0.0026 17.6 11.2 3.2 3 0 0 3 3 3 2 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 PSC72511.1 - 0.00093 19.0 8.8 0.092 12.6 2.9 2.4 2 0 0 2 2 2 2 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 PSC72511.1 - 0.0013 18.5 9.9 0.0013 18.5 9.9 4.0 4 1 0 4 4 4 1 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 PSC72511.1 - 0.0019 18.3 21.1 0.013 15.6 6.3 3.4 4 0 0 4 4 4 2 zinc RING finger of MSL2 DUF501 PF04417.12 PSC72511.1 - 0.12 12.1 1.4 0.22 11.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF501) DNA_pol_phi PF04931.13 PSC72511.1 - 0.58 8.2 10.8 0.96 7.5 10.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi zf-rbx1 PF12678.7 PSC72511.1 - 2.4 8.5 21.6 0.17 12.2 8.2 3.3 3 0 0 3 3 3 0 RING-H2 zinc finger domain eIF-1a PF01176.19 PSC72512.1 - 6.3e-23 80.4 0.2 9.6e-23 79.8 0.2 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DUF2358 PF10184.9 PSC72513.1 - 4.2e-15 56.0 0.0 6e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) DUF4101 PF13355.6 PSC72514.1 - 1.4e-23 83.6 0.4 2.4e-23 82.8 0.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4101) HHA PF05321.11 PSC72514.1 - 0.17 12.2 0.0 0.52 10.7 0.0 1.8 1 0 0 1 1 1 0 Haemolysin expression modulating protein Prp18 PF02840.15 PSC72516.1 - 8.8e-53 178.2 0.1 1.8e-52 177.2 0.1 1.6 1 0 0 1 1 1 1 Prp18 domain Acyl-CoA_dh_M PF02770.19 PSC72516.1 - 1.8e-16 60.1 0.0 3.7e-16 59.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.19 PSC72516.1 - 5.2e-11 42.4 0.0 9.6e-11 41.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase PRP4 PF08799.11 PSC72516.1 - 2.4e-10 39.8 1.4 2.4e-10 39.8 1.4 2.4 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like Acyl-CoA_dh_1 PF00441.24 PSC72516.1 - 0.0013 19.0 0.8 0.0039 17.4 0.1 2.3 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain DUF382 PF04037.13 PSC72516.1 - 0.31 11.2 0.8 1.2 9.3 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF382) UQ_con PF00179.26 PSC72517.1 - 1.5e-51 173.7 0.0 1.7e-51 173.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 PSC72517.1 - 0.0082 16.4 0.0 0.013 15.8 0.0 1.4 1 1 0 1 1 1 1 RWD domain DUF3425 PF11905.8 PSC72517.1 - 0.084 12.8 0.0 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3425) SHIPPO-rpt PF07004.12 PSC72518.1 - 1.8e-05 25.5 37.4 0.0009 20.0 0.2 7.4 7 1 0 7 7 7 4 Sperm-tail PG-rich repeat AAA PF00004.29 PSC72521.1 - 9.4e-42 142.6 0.0 3.7e-41 140.7 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PSC72521.1 - 1.5e-09 37.5 0.1 7.7e-09 35.2 0.1 2.2 2 0 0 2 2 2 1 AAA+ lid domain AAA_2 PF07724.14 PSC72521.1 - 6.3e-06 26.4 0.0 1.4e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 PSC72521.1 - 9.8e-06 25.6 0.1 4e-05 23.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PSC72521.1 - 4.1e-05 24.0 0.1 0.00044 20.7 0.1 2.2 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PSC72521.1 - 7.8e-05 23.0 0.1 0.0062 16.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 PSC72521.1 - 0.00052 19.2 0.0 0.0011 18.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RuvB_N PF05496.12 PSC72521.1 - 0.00079 19.2 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 PSC72521.1 - 0.0011 19.5 0.0 0.0079 16.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 PSC72521.1 - 0.0025 18.1 0.0 0.0041 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PSC72521.1 - 0.0027 17.9 0.0 0.0059 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 PSC72521.1 - 0.0048 17.3 0.0 0.014 15.8 0.0 1.8 2 0 0 2 2 1 1 RNA helicase AAA_24 PF13479.6 PSC72521.1 - 0.0057 16.4 0.1 0.098 12.4 0.0 2.6 2 1 0 2 2 2 1 AAA domain TIP49 PF06068.13 PSC72521.1 - 0.0082 15.4 0.0 0.024 13.9 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain ATPase_2 PF01637.18 PSC72521.1 - 0.0094 15.9 0.0 0.61 10.0 0.0 2.4 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea Mg_chelatase PF01078.21 PSC72521.1 - 0.012 15.0 0.0 0.029 13.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 PSC72521.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_7 PF12775.7 PSC72521.1 - 0.019 14.5 0.0 0.055 13.0 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 PSC72521.1 - 0.039 13.8 0.0 0.086 12.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ATPase PF06745.13 PSC72521.1 - 0.046 13.0 0.1 0.42 9.9 0.0 2.5 3 0 0 3 3 3 0 KaiC Zea_mays_MuDR PF05928.11 PSC72521.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 Zea mays MURB-like protein (MuDR) AAA_14 PF13173.6 PSC72521.1 - 0.059 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Histone PF00125.24 PSC72521.1 - 0.073 13.4 0.1 0.25 11.7 0.1 1.9 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Sigma54_activat PF00158.26 PSC72521.1 - 0.082 12.6 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain Parvo_NS1 PF01057.17 PSC72521.1 - 0.12 11.5 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 PSC72521.1 - 0.14 11.7 0.1 0.59 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain E1-E2_ATPase PF00122.20 PSC72522.1 - 1.6e-20 73.4 0.0 6.8e-19 68.1 0.0 2.4 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 PSC72522.1 - 1.3e-13 51.8 0.1 7.5e-07 29.6 0.0 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PSC72522.1 - 0.0003 20.8 0.0 0.00069 19.6 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Forkhead PF00250.18 PSC72522.1 - 0.027 14.7 0.0 0.071 13.4 0.0 1.7 1 0 0 1 1 1 0 Forkhead domain TFIIA PF03153.13 PSC72522.1 - 2.3 8.1 15.8 3.5 7.5 15.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PALP PF00291.25 PSC72523.1 - 6.2e-66 222.8 1.1 7.8e-66 222.5 1.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_zinc_N PF00107.26 PSC72523.1 - 0.15 12.1 0.4 0.34 10.9 0.4 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase AA_kinase PF00696.28 PSC72524.1 - 9.6e-33 113.8 0.3 1.1e-32 113.5 0.3 1.1 1 0 0 1 1 1 1 Amino acid kinase family Amdase PF17645.1 PSC72524.1 - 0.023 14.3 0.3 0.035 13.7 0.3 1.3 1 0 0 1 1 1 0 Arylmalonate decarboxylase Nucleotid_trans PF03407.16 PSC72525.1 - 8.5e-08 32.4 0.0 1.3e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Nucleotid_trans PF03407.16 PSC72526.1 - 1.1e-07 32.1 0.0 1.7e-07 31.4 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Noelin-1 PF12308.8 PSC72528.1 - 0.39 10.7 2.8 1.1 9.3 0.3 2.4 2 0 0 2 2 2 0 Neurogenesis glycoprotein SelP_N PF04592.14 PSC72528.1 - 0.94 8.8 10.1 2 7.7 10.1 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Secretin_N PF03958.17 PSC72528.1 - 6.3 7.3 11.1 3.7 8.0 0.8 3.6 3 0 0 3 3 3 0 Bacterial type II/III secretion system short domain GSHPx PF00255.19 PSC72529.1 - 4.1e-36 122.8 0.0 9.3e-36 121.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione peroxidase DSHCT PF08148.12 PSC72529.1 - 3.3e-30 104.9 0.4 3.3e-30 104.9 0.4 2.8 3 0 0 3 3 3 1 DSHCT (NUC185) domain DEAD PF00270.29 PSC72529.1 - 4.7e-21 75.3 0.0 8.4e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 PSC72529.1 - 2.8e-10 40.5 0.0 1.3e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PSC72529.1 - 0.00095 19.5 1.3 0.0019 18.5 0.0 2.2 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 PSC72529.1 - 0.0013 18.5 1.5 0.019 14.7 0.2 2.8 1 1 1 2 2 2 1 IstB-like ATP binding protein AhpC-TSA PF00578.21 PSC72529.1 - 0.0035 17.3 0.0 0.0083 16.0 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family AAA_25 PF13481.6 PSC72529.1 - 0.0045 16.6 0.1 0.14 11.8 0.1 2.7 2 0 0 2 2 2 1 AAA domain Helicase_C PF00271.31 PSC72529.1 - 0.0073 16.6 0.0 0.031 14.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PhoH PF02562.16 PSC72529.1 - 0.0077 15.7 0.1 0.015 14.8 0.1 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_19 PF13245.6 PSC72529.1 - 0.0088 16.4 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain DDHD PF02862.17 PSC72529.1 - 0.034 14.3 2.0 0.13 12.4 1.9 1.9 2 0 0 2 2 2 0 DDHD domain DUF4746 PF15928.5 PSC72529.1 - 0.11 11.9 0.5 0.2 11.0 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFIIA PF03153.13 PSC72529.1 - 0.13 12.2 16.8 0.22 11.5 16.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 PSC72529.1 - 0.15 11.7 15.6 0.24 11.0 15.6 1.2 1 0 0 1 1 1 0 Spt20 family V_ATPase_I PF01496.19 PSC72529.1 - 0.78 7.6 3.3 1.2 7.0 3.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Suf PF05843.14 PSC72529.1 - 2.9 7.8 7.1 1.1 9.2 4.1 1.8 2 0 0 2 2 1 0 Suppressor of forked protein (Suf) DUF4820 PF16091.5 PSC72529.1 - 4.6 6.5 7.5 9 5.6 7.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Presenilin PF01080.17 PSC72529.1 - 4.9 5.8 7.5 7.5 5.2 7.5 1.1 1 0 0 1 1 1 0 Presenilin GSHPx PF00255.19 PSC72530.1 - 4.1e-36 122.8 0.0 9.3e-36 121.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione peroxidase DSHCT PF08148.12 PSC72530.1 - 3.3e-30 104.9 0.4 3.3e-30 104.9 0.4 2.8 3 0 0 3 3 3 1 DSHCT (NUC185) domain DEAD PF00270.29 PSC72530.1 - 4.7e-21 75.3 0.0 8.4e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 PSC72530.1 - 2.8e-10 40.4 0.0 1.3e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PSC72530.1 - 0.00095 19.5 1.3 0.0019 18.5 0.0 2.2 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 PSC72530.1 - 0.0013 18.5 1.5 0.019 14.7 0.2 2.8 1 1 1 2 2 2 1 IstB-like ATP binding protein AhpC-TSA PF00578.21 PSC72530.1 - 0.0035 17.2 0.0 0.0083 16.0 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family AAA_25 PF13481.6 PSC72530.1 - 0.0045 16.6 0.1 0.14 11.8 0.1 2.7 2 0 0 2 2 2 1 AAA domain Helicase_C PF00271.31 PSC72530.1 - 0.0073 16.6 0.0 0.031 14.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PhoH PF02562.16 PSC72530.1 - 0.0077 15.7 0.1 0.015 14.8 0.1 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_19 PF13245.6 PSC72530.1 - 0.0088 16.4 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain DDHD PF02862.17 PSC72530.1 - 0.028 14.6 1.6 0.13 12.4 1.9 1.9 2 0 0 2 2 2 0 DDHD domain DUF4746 PF15928.5 PSC72530.1 - 0.11 11.9 0.5 0.2 11.0 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFIIA PF03153.13 PSC72530.1 - 0.13 12.2 16.8 0.22 11.5 16.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 PSC72530.1 - 0.15 11.7 15.6 0.24 11.0 15.6 1.2 1 0 0 1 1 1 0 Spt20 family V_ATPase_I PF01496.19 PSC72530.1 - 0.79 7.6 3.3 1.2 7.0 3.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Suf PF05843.14 PSC72530.1 - 2.9 7.8 7.1 1.1 9.2 4.1 1.8 2 0 0 2 2 1 0 Suppressor of forked protein (Suf) DUF4820 PF16091.5 PSC72530.1 - 4.7 6.5 7.5 9 5.6 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Presenilin PF01080.17 PSC72530.1 - 4.9 5.8 7.5 7.5 5.2 7.5 1.1 1 0 0 1 1 1 0 Presenilin GSHPx PF00255.19 PSC72531.1 - 4.2e-36 122.8 0.0 9.4e-36 121.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione peroxidase DSHCT PF08148.12 PSC72531.1 - 3.4e-30 104.9 0.4 3.4e-30 104.9 0.4 2.8 3 0 0 3 3 3 1 DSHCT (NUC185) domain DEAD PF00270.29 PSC72531.1 - 4.8e-21 75.3 0.0 8.5e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 PSC72531.1 - 2.9e-10 40.4 0.0 1.3e-09 38.3 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PSC72531.1 - 0.00093 19.5 1.3 0.0019 18.4 0.0 2.1 2 0 0 2 2 1 1 AAA domain IstB_IS21 PF01695.17 PSC72531.1 - 0.0013 18.5 1.5 0.019 14.7 0.2 2.8 1 1 1 2 2 2 1 IstB-like ATP binding protein AhpC-TSA PF00578.21 PSC72531.1 - 0.0036 17.2 0.0 0.0084 16.0 0.0 1.6 1 0 0 1 1 1 1 AhpC/TSA family AAA_25 PF13481.6 PSC72531.1 - 0.0046 16.5 0.1 0.14 11.7 0.1 2.7 2 0 0 2 2 2 1 AAA domain Helicase_C PF00271.31 PSC72531.1 - 0.0074 16.6 0.0 0.032 14.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain PhoH PF02562.16 PSC72531.1 - 0.0078 15.7 0.1 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 PhoH-like protein AAA_19 PF13245.6 PSC72531.1 - 0.009 16.4 0.0 0.022 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain DDHD PF02862.17 PSC72531.1 - 0.027 14.6 1.5 0.14 12.3 1.9 1.9 2 0 0 2 2 2 0 DDHD domain DUF4746 PF15928.5 PSC72531.1 - 0.11 11.9 0.5 0.21 11.0 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) TFIIA PF03153.13 PSC72531.1 - 0.13 12.2 16.8 0.23 11.4 16.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 PSC72531.1 - 0.15 11.7 15.6 0.24 11.0 15.6 1.2 1 0 0 1 1 1 0 Spt20 family V_ATPase_I PF01496.19 PSC72531.1 - 0.8 7.6 3.3 1.2 6.9 3.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Suf PF05843.14 PSC72531.1 - 2.9 7.8 7.1 1.1 9.2 4.1 1.7 2 0 0 2 2 1 0 Suppressor of forked protein (Suf) DUF4820 PF16091.5 PSC72531.1 - 4.8 6.5 7.5 9.1 5.6 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Presenilin PF01080.17 PSC72531.1 - 4.9 5.8 7.5 7.6 5.2 7.5 1.1 1 0 0 1 1 1 0 Presenilin Hexapep PF00132.24 PSC72532.1 - 3.3e-10 39.3 0.1 0.037 13.8 0.0 4.2 4 0 0 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 PSC72532.1 - 0.00093 18.9 0.3 0.054 13.3 0.3 2.7 1 1 1 2 2 2 2 Hexapeptide repeat of succinyl-transferase ELFV_dehydrog PF00208.21 PSC72533.1 - 1e-64 218.6 0.0 1.4e-64 218.1 0.0 1.1 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.18 PSC72533.1 - 1.2e-52 177.2 0.0 2e-52 176.5 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain AdoHcyase_NAD PF00670.21 PSC72533.1 - 0.0021 18.2 0.3 0.009 16.1 0.3 1.9 2 0 0 2 2 2 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 PSC72533.1 - 0.017 14.4 0.3 0.032 13.6 0.3 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain SLC12 PF03522.15 PSC72535.1 - 6.9 5.6 8.9 7.8 5.4 8.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 PSC72535.1 - 8.5 5.0 10.6 9.6 4.8 10.6 1.1 1 0 0 1 1 1 0 Presenilin PRiA4_ORF3 PF07929.11 PSC72536.1 - 1e-27 96.9 0.0 2e-27 96.0 0.0 1.4 1 0 0 1 1 1 1 Plasmid pRiA4b ORF-3-like protein zf-CCHC_3 PF13917.6 PSC72536.1 - 5.7e-18 64.6 4.2 2.3e-17 62.7 4.2 2.2 1 0 0 1 1 1 1 Zinc knuckle zf-MYND PF01753.18 PSC72536.1 - 3.9e-10 39.6 7.4 3.9e-10 39.6 7.4 4.8 6 0 0 6 6 6 1 MYND finger zf-C3HC4_3 PF13920.6 PSC72536.1 - 1.9e-05 24.4 5.4 1.9e-05 24.4 5.4 4.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RanBP PF00641.18 PSC72536.1 - 0.00087 18.6 2.4 0.00087 18.6 2.4 3.4 3 0 0 3 3 3 1 Zn-finger in Ran binding protein and others zf-CCHC PF00098.23 PSC72536.1 - 0.3 11.3 12.2 0.46 10.7 1.1 4.0 3 0 0 3 3 3 0 Zinc knuckle SUIM_assoc PF16619.5 PSC72536.1 - 0.41 10.7 25.1 0.57 10.3 2.3 4.5 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 zf-C2H2_6 PF13912.6 PSC72536.1 - 3.2 7.9 13.8 2 8.5 1.8 4.0 4 0 0 4 4 4 0 C2H2-type zinc finger Macoilin PF09726.9 PSC72536.1 - 4 5.9 23.6 8.6 4.8 23.6 1.5 1 0 0 1 1 1 0 Macoilin family Anti-TRAP PF15777.5 PSC72536.1 - 9.8 6.2 7.4 24 5.0 6.0 2.5 2 0 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein RNase_PH PF01138.21 PSC72537.1 - 1.9e-27 96.4 0.0 1.7e-15 57.7 0.0 2.8 3 0 0 3 3 3 2 3' exoribonuclease family, domain 1 S1 PF00575.23 PSC72537.1 - 7e-19 68.0 0.6 1.8e-11 44.2 0.1 3.6 4 0 0 4 4 4 2 S1 RNA binding domain RNase_PH_C PF03725.15 PSC72537.1 - 6.4e-17 61.3 1.0 1.1e-09 38.1 0.0 2.5 2 0 0 2 2 2 2 3' exoribonuclease family, domain 2 KH_1 PF00013.29 PSC72537.1 - 1.7e-12 47.0 0.4 8.6e-12 44.7 0.4 2.2 2 0 0 2 2 2 1 KH domain PNPase PF03726.14 PSC72537.1 - 1.2e-08 35.3 0.3 0.00016 22.1 0.0 2.5 2 0 0 2 2 2 2 Polyribonucleotide nucleotidyltransferase, RNA binding domain RcpC PF16976.5 PSC72537.1 - 1.2 9.2 5.7 2.1 8.4 0.1 2.9 3 0 0 3 3 3 0 Flp pilus assembly protein RcpC/CpaB CLP_protease PF00574.23 PSC72538.1 - 3e-47 160.9 0.0 3.9e-47 160.5 0.0 1.1 1 0 0 1 1 1 1 Clp protease ECH_1 PF00378.20 PSC72538.1 - 0.055 12.8 0.0 0.081 12.2 0.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DCX PF03607.17 PSC72539.1 - 8.3e-05 22.6 0.0 0.00076 19.5 0.0 2.4 3 0 0 3 3 3 1 Doublecortin ENOD93 PF03386.14 PSC72539.1 - 3 7.8 6.2 5.4 7.0 5.5 1.9 1 1 1 2 2 2 0 Early nodulin 93 ENOD93 protein GIDA PF01134.22 PSC72540.1 - 1.1e-124 416.5 0.0 1.9e-62 211.6 0.0 3.1 2 1 1 3 3 3 2 Glucose inhibited division protein A GIDA_assoc PF13932.6 PSC72540.1 - 3.8e-57 193.9 0.0 6.3e-57 193.2 0.0 1.4 1 0 0 1 1 1 1 GidA associated domain VPS13 PF16908.5 PSC72540.1 - 2.9e-54 184.4 0.0 1.3e-53 182.3 0.0 2.0 2 0 0 2 2 2 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 PSC72540.1 - 1.7e-30 105.5 0.0 3.3e-30 104.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of Chorein or VPS13 Vps62 PF06101.11 PSC72540.1 - 3.3e-29 101.6 0.1 5.2e-09 34.9 0.0 5.2 3 3 3 6 6 6 5 Vacuolar protein sorting-associated protein 62 VPS13_mid_rpt PF16910.5 PSC72540.1 - 2.2e-27 96.0 0.0 7.7e-26 91.0 0.0 3.0 3 0 0 3 3 3 1 Repeating coiled region of VPS13 VPS13_C PF16909.5 PSC72540.1 - 6.4e-08 32.6 0.9 0.0017 18.1 0.0 2.4 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 PSC72540.1 - 2.5e-06 27.7 1.1 9.2e-06 25.9 0.0 2.6 2 0 0 2 2 1 1 Autophagy-related protein C terminal domain Pex24p PF06398.11 PSC72540.1 - 2.7e-06 26.6 0.0 4e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin FAD_oxidored PF12831.7 PSC72540.1 - 3.5e-06 26.7 3.0 3.5e-06 26.7 3.0 1.9 2 0 0 2 2 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 PSC72540.1 - 0.0051 16.1 1.1 0.01 15.1 1.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase PH PF00169.29 PSC72540.1 - 0.069 13.7 0.0 0.17 12.4 0.0 1.6 1 0 0 1 1 1 0 PH domain AlaDh_PNT_C PF01262.21 PSC72540.1 - 0.072 12.4 3.0 0.19 11.0 3.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox PF00070.27 PSC72540.1 - 0.17 12.5 0.4 0.39 11.3 0.4 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PSC72540.1 - 0.21 10.8 0.0 0.4 9.9 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Apt1 PF10351.9 PSC72540.1 - 0.24 10.2 0.0 2.6 6.8 0.0 2.0 2 0 0 2 2 2 0 Golgi-body localisation protein domain AMPK1_CBM PF16561.5 PSC72542.1 - 1.6e-11 44.2 0.0 3.2e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase DSPc PF00782.20 PSC72542.1 - 1.5e-10 41.0 0.0 2.3e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Mig-14 PF07395.11 PSC72542.1 - 0.22 10.9 0.0 0.34 10.2 0.0 1.2 1 0 0 1 1 1 0 Mig-14 Pkinase PF00069.25 PSC72543.1 - 5.5e-24 84.9 0.0 5.7e-16 58.7 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain CAP PF00188.26 PSC72543.1 - 1.4e-19 71.2 0.2 3.1e-19 70.1 0.2 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Pkinase_Tyr PF07714.17 PSC72543.1 - 9.3e-08 31.7 0.0 0.00019 20.8 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase ShK PF01549.24 PSC72543.1 - 0.04 14.5 12.4 0.11 13.1 12.4 1.8 1 1 0 1 1 1 0 ShK domain-like BRO1 PF03097.18 PSC72544.1 - 3.7e-90 302.5 7.5 3.7e-90 302.5 7.5 1.7 2 0 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 PSC72544.1 - 2.9e-60 204.1 0.0 2.9e-60 204.1 0.0 2.6 3 1 0 3 3 3 1 ALIX V-shaped domain binding to HIV DUF2483 PF10656.9 PSC72544.1 - 0.15 12.2 0.0 0.31 11.3 0.0 1.4 1 0 0 1 1 1 0 Hypothetical protein of unknown function (DUF2483) Aldo_ket_red PF00248.21 PSC72545.1 - 6.4e-55 186.4 0.0 1.1e-54 185.7 0.0 1.3 1 1 0 1 1 1 1 Aldo/keto reductase family HEAT PF02985.22 PSC72545.1 - 0.32 11.4 3.5 1.6 9.2 0.1 3.1 2 0 0 2 2 2 0 HEAT repeat LRR_8 PF13855.6 PSC72546.1 - 5.9e-12 45.2 5.7 0.0028 17.4 0.1 4.4 4 0 0 4 4 4 3 Leucine rich repeat Chloroa_b-bind PF00504.21 PSC72546.1 - 4.8e-09 36.9 5.8 0.00055 20.5 1.0 2.6 1 1 1 2 2 2 2 Chlorophyll A-B binding protein F-box-like PF12937.7 PSC72546.1 - 1.3e-07 31.4 11.8 0.0012 18.7 1.7 3.8 4 0 0 4 4 4 2 F-box-like LRR_4 PF12799.7 PSC72546.1 - 0.0001 22.6 6.1 0.35 11.4 0.0 4.9 6 0 0 6 6 6 2 Leucine Rich repeats (2 copies) F-box PF00646.33 PSC72546.1 - 0.00075 19.3 0.9 0.0089 15.9 0.5 2.7 2 0 0 2 2 2 1 F-box domain LRR_9 PF14580.6 PSC72546.1 - 0.25 10.8 0.0 2.7 7.5 0.0 2.4 2 1 1 3 3 3 0 Leucine-rich repeat Conotoxin_I2 PF17557.2 PSC72546.1 - 4.1 7.6 17.5 6 7.1 3.9 2.6 2 0 0 2 2 2 0 I2-superfamily conotoxins SAD_SRA PF02182.17 PSC72547.1 - 3e-39 134.2 0.0 3e-39 134.2 0.0 2.4 2 0 0 2 2 2 1 SAD/SRA domain SET PF00856.28 PSC72547.1 - 3.2e-14 53.7 9.6 2.1e-13 51.0 0.0 3.7 2 2 0 2 2 2 1 SET domain Ndc1_Nup PF09531.10 PSC72547.1 - 0.043 12.5 18.5 0.061 12.0 18.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pre-SET PF05033.16 PSC72547.1 - 0.59 10.8 0.0 0.59 10.8 0.0 3.6 5 0 0 5 5 5 0 Pre-SET motif SpoIIP PF07454.11 PSC72547.1 - 1.5 8.2 9.8 2.8 7.3 9.8 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SOG2 PF10428.9 PSC72547.1 - 1.5 7.9 14.8 2.1 7.5 14.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Presenilin PF01080.17 PSC72547.1 - 2.4 6.8 19.2 4.1 6.1 19.2 1.4 1 0 0 1 1 1 0 Presenilin DUF4569 PF15133.6 PSC72547.1 - 8.3 6.0 13.0 17 5.0 13.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4569) Macoilin PF09726.9 PSC72547.1 - 9.7 4.6 12.5 15 4.0 12.5 1.3 1 0 0 1 1 1 0 Macoilin family Nop53 PF07767.11 PSC72548.1 - 0.049 13.0 24.3 0.14 11.6 24.3 1.8 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Herpes_UL92 PF03048.14 PSC72549.1 - 0.013 15.3 0.6 0.016 15.0 0.6 1.1 1 0 0 1 1 1 0 UL92 family DHHC PF01529.20 PSC72550.1 - 1.1e-31 109.8 2.9 1.1e-31 109.8 2.9 2.1 3 0 0 3 3 3 1 DHHC palmitoyltransferase DUF2244 PF10003.9 PSC72550.1 - 0.43 10.2 0.1 0.43 10.2 0.1 3.2 4 0 0 4 4 4 0 Integral membrane protein (DUF2244) SRCR PF00530.18 PSC72551.1 - 2.7e-65 217.1 10.8 1.8e-18 66.9 0.2 5.2 5 0 0 5 5 5 5 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PSC72551.1 - 4.4e-07 30.3 6.9 0.016 15.7 0.0 5.1 5 1 0 5 5 5 2 Scavenger receptor cysteine-rich domain LRR_4 PF12799.7 PSC72551.1 - 2.3e-05 24.6 0.4 0.36 11.3 0.1 2.8 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC72551.1 - 0.00025 20.7 0.2 0.068 12.9 0.1 2.8 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 PSC72551.1 - 0.0071 16.3 0.7 32 4.9 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 PSC72551.1 - 0.086 13.4 0.4 35 5.5 0.0 3.9 3 0 0 3 3 3 0 Leucine Rich Repeat ECH_1 PF00378.20 PSC72554.1 - 7.5e-48 163.0 0.7 1.3e-47 162.2 0.8 1.4 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PSC72554.1 - 4e-28 98.9 0.2 4.9e-28 98.6 0.2 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase HMGL-like PF00682.19 PSC72556.1 - 1.3e-83 280.6 0.2 1.3e-83 280.6 0.2 1.5 2 0 0 2 2 2 1 HMGL-like LeuA_dimer PF08502.10 PSC72556.1 - 9.3e-33 113.0 0.0 2.8e-32 111.4 0.0 1.8 1 1 0 1 1 1 1 LeuA allosteric (dimerisation) domain Lactamase_B PF00753.27 PSC72557.1 - 0.054 13.5 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily zf-MYND PF01753.18 PSC72557.1 - 0.065 13.3 1.5 0.13 12.4 1.5 1.5 1 0 0 1 1 1 0 MYND finger BPD_transp_2 PF02653.16 PSC72557.1 - 0.071 12.3 3.9 0.16 11.1 3.9 1.6 1 1 0 1 1 1 0 Branched-chain amino acid transport system / permease component UQ_con PF00179.26 PSC72558.1 - 1.5e-27 96.0 0.0 1.8e-26 92.4 0.0 2.4 3 0 0 3 3 3 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PSC72558.1 - 0.002 17.9 0.1 3.1 7.5 0.0 3.0 3 0 0 3 3 3 2 Prokaryotic E2 family B UEV PF05743.13 PSC72558.1 - 0.0082 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 PSC72558.1 - 0.04 14.2 0.0 0.091 13.1 0.0 1.5 1 0 0 1 1 1 0 RWD domain CCDC53 PF10152.9 PSC72558.1 - 5.8 7.3 6.3 13 6.1 6.3 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex UQ_con PF00179.26 PSC72559.1 - 1.5e-27 96.0 0.0 1.8e-26 92.4 0.0 2.4 3 0 0 3 3 3 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PSC72559.1 - 0.002 17.9 0.1 3.1 7.5 0.0 3.0 3 0 0 3 3 3 2 Prokaryotic E2 family B UEV PF05743.13 PSC72559.1 - 0.0083 16.0 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 PSC72559.1 - 0.041 14.2 0.0 0.091 13.1 0.0 1.5 1 0 0 1 1 1 0 RWD domain CCDC53 PF10152.9 PSC72559.1 - 5.8 7.3 6.3 13 6.1 6.3 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DENN PF02141.21 PSC72560.1 - 5.9e-19 68.7 0.3 3e-15 56.6 0.3 2.8 2 1 0 2 2 2 2 DENN (AEX-3) domain dDENN PF03455.19 PSC72560.1 - 2.2e-05 24.4 0.4 5e-05 23.2 0.4 1.6 1 0 0 1 1 1 1 dDENN domain uDENN PF03456.18 PSC72560.1 - 0.034 14.9 0.1 0.034 14.9 0.1 2.1 2 0 0 2 2 2 0 uDENN domain zf-RING_2 PF13639.6 PSC72561.1 - 4.7e-12 46.0 3.5 7.3e-12 45.4 3.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PSC72561.1 - 1.6e-09 37.4 2.0 2.7e-09 36.6 2.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PSC72561.1 - 3.4e-08 33.2 3.4 5.4e-08 32.6 3.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC72561.1 - 1e-07 31.7 2.5 1.7e-07 31.0 2.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PSC72561.1 - 3.7e-06 27.1 2.1 8e-06 26.1 2.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PSC72561.1 - 1.1e-05 25.3 2.1 1.7e-05 24.7 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PSC72561.1 - 1.4e-05 24.9 1.3 2.1e-05 24.3 1.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PSC72561.1 - 0.00011 22.2 0.8 0.00019 21.4 0.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 PSC72561.1 - 0.00034 20.6 3.8 0.00065 19.7 3.8 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 PSC72561.1 - 0.0074 16.1 2.2 0.014 15.2 2.2 1.3 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 PSC72561.1 - 0.028 14.0 2.1 0.028 14.0 2.1 1.7 2 0 0 2 2 1 0 Zinc-ribbon, C4HC2 type PHD PF00628.29 PSC72561.1 - 0.03 14.2 2.3 0.048 13.6 2.3 1.3 1 0 0 1 1 1 0 PHD-finger zf-C3HC4_4 PF15227.6 PSC72561.1 - 0.15 12.3 3.4 0.26 11.5 3.4 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.11 PSC72561.1 - 0.24 11.5 2.0 0.51 10.5 2.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) RINGv PF12906.7 PSC72561.1 - 0.24 11.5 3.7 0.48 10.6 3.7 1.5 1 0 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.6 PSC72561.1 - 0.77 9.7 3.3 0.61 10.1 0.4 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-RING-like PF08746.11 PSC72561.1 - 0.81 10.0 3.0 1.5 9.2 3.0 1.5 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 PSC72561.1 - 1.5 9.1 6.4 8.9 6.6 6.4 2.1 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3H2C3 PF17122.5 PSC72561.1 - 1.5 8.9 6.4 6.6 6.9 6.4 2.0 1 1 0 1 1 1 0 Zinc-finger SF3b1 PF08920.10 PSC72562.1 - 4.5e-39 133.6 5.7 4.5e-39 133.6 5.7 3.9 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT PF02985.22 PSC72562.1 - 1.4e-10 40.5 6.8 1.6 9.2 0.0 9.5 10 0 0 10 10 10 2 HEAT repeat HEAT_EZ PF13513.6 PSC72562.1 - 5.7e-09 36.3 0.7 0.053 14.0 0.0 7.7 7 1 1 8 8 8 1 HEAT-like repeat HEAT_2 PF13646.6 PSC72562.1 - 4e-08 33.5 5.5 0.69 10.3 0.0 7.2 4 3 5 9 9 8 3 HEAT repeats Cnd1 PF12717.7 PSC72562.1 - 4e-05 23.7 8.0 1.6 8.8 0.0 6.0 7 0 0 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 PSC72562.1 - 0.0025 16.5 0.3 0.18 10.3 0.0 2.3 2 0 0 2 2 2 2 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 PSC72562.1 - 0.0034 18.0 0.3 6.5 7.4 0.0 4.7 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region NUC173 PF08161.12 PSC72562.1 - 0.012 15.3 0.4 14 5.3 0.0 4.0 5 0 0 5 5 5 0 NUC173 domain UME PF08064.13 PSC72562.1 - 0.018 15.0 0.2 3.4 7.6 0.0 3.8 4 0 0 4 4 4 0 UME (NUC010) domain Ecm29 PF13001.7 PSC72562.1 - 0.074 11.7 0.0 0.22 10.1 0.0 1.9 1 1 1 2 2 2 0 Proteasome stabiliser Dopey_N PF04118.14 PSC72562.1 - 0.17 11.0 0.8 8 5.5 0.0 3.4 3 1 1 4 4 4 0 Dopey, N-terminal TAF6_C PF07571.13 PSC72562.1 - 0.18 12.2 0.0 1.1 9.6 0.0 2.5 2 0 0 2 2 2 0 TAF6 C-terminal HEAT repeat domain FKBP_C PF00254.28 PSC72563.1 - 2.4e-14 53.4 0.0 4e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF3767 PF12597.8 PSC72563.1 - 0.05 13.4 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3767) PsbQ PF05757.11 PSC72563.1 - 0.068 12.9 3.8 0.11 12.2 3.8 1.4 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) ENOD93 PF03386.14 PSC72563.1 - 0.087 12.7 2.7 0.31 10.9 2.7 1.8 1 1 0 1 1 1 0 Early nodulin 93 ENOD93 protein VKOR PF07884.14 PSC72564.1 - 7.5e-22 77.8 9.3 1.3e-21 77.1 9.3 1.4 1 0 0 1 1 1 1 Vitamin K epoxide reductase family DSBA PF01323.20 PSC72564.1 - 0.034 13.9 0.0 0.034 13.9 0.0 1.9 2 1 0 2 2 2 0 DSBA-like thioredoxin domain Thioredoxin_2 PF13098.6 PSC72564.1 - 0.053 14.0 0.0 0.085 13.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like domain Rib_5-P_isom_A PF06026.14 PSC72565.1 - 5.1e-59 198.8 0.2 8.1e-59 198.1 0.2 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Ribosomal_L36e PF01158.18 PSC72565.1 - 2.9e-36 123.6 9.2 6.1e-36 122.6 9.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L36e DUF563 PF04577.14 PSC72565.1 - 2.8e-14 53.8 0.0 9.2e-14 52.1 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF563) DeoRC PF00455.22 PSC72565.1 - 0.053 13.5 1.7 0.06 13.3 0.0 2.0 3 0 0 3 3 3 0 DeoR C terminal sensor domain Rib_5-P_isom_A PF06026.14 PSC72566.1 - 5.1e-59 198.8 0.2 8.1e-59 198.1 0.2 1.3 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Ribosomal_L36e PF01158.18 PSC72566.1 - 2.9e-36 123.6 9.2 6.1e-36 122.6 9.2 1.5 1 0 0 1 1 1 1 Ribosomal protein L36e DUF563 PF04577.14 PSC72566.1 - 2.8e-14 53.8 0.0 9.2e-14 52.1 0.0 1.9 2 1 0 2 2 2 1 Protein of unknown function (DUF563) DeoRC PF00455.22 PSC72566.1 - 0.053 13.5 1.7 0.06 13.3 0.0 2.0 3 0 0 3 3 3 0 DeoR C terminal sensor domain CAP_N PF01213.19 PSC72567.1 - 0.57 9.6 9.3 0.86 9.0 9.3 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.11 PSC72567.1 - 0.89 9.6 4.1 1.4 9.0 4.1 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Dak2 PF02734.17 PSC72568.1 - 2.4 8.0 10.3 2.8 7.8 6.7 2.4 2 1 0 2 2 2 0 DAK2 domain Polysacc_deac_1 PF01522.21 PSC72569.1 - 3.7e-07 30.1 0.0 6.3e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase 2OG-FeII_Oxy_3 PF13640.6 PSC72570.1 - 5.8e-19 68.8 0.2 3.1e-18 66.4 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 PSC72570.1 - 1e-05 25.9 10.0 6.7e-05 23.3 10.0 2.3 1 1 0 1 1 1 1 ShK domain-like 2OG-FeII_Oxy PF03171.20 PSC72570.1 - 0.00022 21.7 0.0 0.00039 20.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 PSC72570.1 - 0.032 13.4 0.0 0.046 12.8 0.0 1.1 1 0 0 1 1 1 0 Poxvirus C4/C10 protein HNH PF01844.23 PSC72570.1 - 0.033 14.4 0.7 7.1 6.9 0.1 3.2 3 0 0 3 3 3 0 HNH endonuclease 2OG-FeII_Oxy_3 PF13640.6 PSC72571.1 - 5.3e-19 68.9 0.2 2.9e-18 66.5 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 PSC72571.1 - 9.9e-06 26.0 10.1 6.7e-05 23.3 10.1 2.3 1 1 0 1 1 1 1 ShK domain-like 2OG-FeII_Oxy PF03171.20 PSC72571.1 - 0.0002 21.8 0.0 0.00036 21.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily HNH PF01844.23 PSC72571.1 - 0.029 14.5 0.7 6.8 6.9 0.1 3.2 3 0 0 3 3 3 0 HNH endonuclease Pox_C4_C10 PF03336.13 PSC72571.1 - 0.03 13.4 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Poxvirus C4/C10 protein RPE65 PF03055.15 PSC72572.1 - 3.3e-110 369.4 0.0 4e-110 369.2 0.0 1.1 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein AMP-binding PF00501.28 PSC72573.1 - 2.5e-52 177.9 0.0 3.9e-44 150.9 0.0 2.5 2 0 0 2 2 2 2 AMP-binding enzyme SBF_like PF13593.6 PSC72573.1 - 8e-44 150.2 29.3 1.3e-43 149.5 29.3 1.4 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 PSC72573.1 - 7e-10 38.9 13.2 1.4e-09 37.9 13.2 1.5 1 0 0 1 1 1 1 Sodium Bile acid symporter family PQQ PF01011.21 PSC72573.1 - 3e-08 33.2 0.1 0.0025 17.6 0.0 4.5 4 0 0 4 4 4 2 PQQ enzyme repeat AMP-binding_C PF13193.6 PSC72573.1 - 3e-07 31.3 0.0 3e-07 31.3 0.0 3.3 3 0 0 3 3 3 1 AMP-binding enzyme C-terminal domain PQQ_2 PF13360.6 PSC72573.1 - 9.7e-06 25.3 12.9 0.00064 19.4 4.5 4.0 3 1 1 4 4 4 2 PQQ-like domain PQQ_3 PF13570.6 PSC72573.1 - 0.00052 20.4 15.2 0.17 12.4 1.5 6.8 7 0 0 7 7 7 2 PQQ-like domain SCAMP PF04144.13 PSC72574.1 - 8e-47 159.8 11.4 1e-46 159.4 11.4 1.1 1 0 0 1 1 1 1 SCAMP family AP2 PF00847.20 PSC72574.1 - 1.5e-06 28.3 0.1 3.9e-06 27.0 0.1 1.7 1 0 0 1 1 1 1 AP2 domain PK PF00224.21 PSC72575.1 - 6.3e-110 367.3 0.2 7.9e-110 367.0 0.2 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 PSC72575.1 - 7.5e-18 64.9 0.0 1.8e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 PSC72575.1 - 0.00087 18.5 0.1 0.0026 16.9 0.1 1.8 1 1 1 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family LysM PF01476.20 PSC72576.1 - 2.3e-06 27.6 0.0 4.6e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 LysM domain Esterase_phd PF10503.9 PSC72576.1 - 0.00034 20.2 1.5 0.01 15.3 0.2 3.1 2 1 0 2 2 2 1 Esterase PHB depolymerase DNA_pol_viral_C PF00336.18 PSC72576.1 - 0.096 12.1 0.0 3.5 7.0 0.0 2.2 2 0 0 2 2 2 0 DNA polymerase (viral) C-terminal domain SPC12 PF06645.13 PSC72576.1 - 0.18 11.9 0.2 1 9.5 0.0 2.3 2 0 0 2 2 2 0 Microsomal signal peptidase 12 kDa subunit (SPC12) DUF4131 PF13567.6 PSC72576.1 - 1.6 8.4 3.9 6.5 6.4 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) CcmD PF04995.14 PSC72576.1 - 2.6 8.2 7.0 2.9 8.1 1.5 2.8 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Pkinase_Tyr PF07714.17 PSC72577.1 - 7e-49 166.4 0.0 1.7e-48 165.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC72577.1 - 1.4e-43 149.2 0.0 2.9e-43 148.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain PAN_4 PF14295.6 PSC72577.1 - 8.3e-12 44.8 17.8 4.3e-07 29.7 5.6 2.7 2 0 0 2 2 2 2 PAN domain LysM PF01476.20 PSC72577.1 - 4.9e-09 36.1 0.0 1.3e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 LysM domain Polysacc_deac_1 PF01522.21 PSC72577.1 - 6.9e-07 29.2 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Phage_holin_2_4 PF16082.5 PSC72577.1 - 0.13 12.0 2.4 0.61 9.9 2.4 2.1 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like stn_TNFRSF12A PF12191.8 PSC72577.1 - 0.71 10.1 4.6 1.7 8.9 0.4 2.7 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain MANEC PF07502.14 PSC72577.1 - 1.2 9.5 7.0 6.4 7.1 1.5 2.5 2 0 0 2 2 2 0 MANEC domain SUIM_assoc PF16619.5 PSC72577.1 - 1.2 9.2 11.6 2.9 8.0 11.6 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 PepSY_TM PF03929.16 PSC72577.1 - 2.3 7.8 6.3 0.47 10.1 0.1 2.5 3 0 0 3 3 3 0 PepSY-associated TM region Pkinase_Tyr PF07714.17 PSC72578.1 - 7e-49 166.4 0.0 1.7e-48 165.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC72578.1 - 1.4e-43 149.2 0.0 2.9e-43 148.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain PAN_4 PF14295.6 PSC72578.1 - 8.2e-12 44.8 17.8 4.3e-07 29.7 5.6 2.8 2 0 0 2 2 2 2 PAN domain LysM PF01476.20 PSC72578.1 - 4.9e-09 36.1 0.0 1.3e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 LysM domain Polysacc_deac_1 PF01522.21 PSC72578.1 - 7e-07 29.2 0.0 1.4e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase Phage_holin_2_4 PF16082.5 PSC72578.1 - 0.13 12.0 2.4 0.61 9.9 2.4 2.1 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like stn_TNFRSF12A PF12191.8 PSC72578.1 - 0.71 10.1 4.6 1.7 8.9 0.4 2.7 2 0 0 2 2 2 0 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain MANEC PF07502.14 PSC72578.1 - 1.2 9.5 7.0 6.4 7.1 1.5 2.5 2 0 0 2 2 2 0 MANEC domain SUIM_assoc PF16619.5 PSC72578.1 - 1.2 9.2 11.6 2.9 8.0 11.6 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 PepSY_TM PF03929.16 PSC72578.1 - 2.6 7.6 6.5 0.47 10.1 0.1 2.5 3 0 0 3 3 3 0 PepSY-associated TM region Lipase_3 PF01764.25 PSC72579.1 - 6.5e-14 52.0 0.0 1.2e-13 51.2 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) YjbE PF11106.8 PSC72579.1 - 0.0013 18.9 11.4 0.0013 18.9 11.4 3.4 3 0 0 3 3 3 1 Exopolysaccharide production protein YjbE Thioesterase PF00975.20 PSC72579.1 - 0.0021 18.2 0.7 0.0039 17.4 0.7 1.4 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 PSC72579.1 - 0.0056 16.0 1.4 0.01 15.2 0.3 1.8 2 0 0 2 2 2 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 PSC72579.1 - 0.027 14.2 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 PSC72579.1 - 0.058 13.0 0.0 0.16 11.5 0.1 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.8 PSC72579.1 - 0.28 10.7 0.0 0.5 9.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) SBP PF03110.14 PSC72580.1 - 2.7e-23 82.1 7.6 2.7e-23 82.1 7.6 2.0 2 0 0 2 2 2 1 SBP domain Hydin_ADK PF17213.3 PSC72580.1 - 0.26 11.5 11.9 0.55 10.5 11.9 1.5 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Rtf2 PF04641.12 PSC72580.1 - 2.5 7.4 10.0 3.9 6.7 10.0 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger Presenilin PF01080.17 PSC72580.1 - 3.1 6.5 9.9 4.3 6.0 9.9 1.2 1 0 0 1 1 1 0 Presenilin DUF4551 PF15087.6 PSC72580.1 - 7.7 5.2 10.6 9.8 4.9 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUF98 PF01947.16 PSC72581.1 - 2.1e-54 183.6 0.0 7.7e-54 181.7 0.0 1.7 2 0 0 2 2 2 1 p-hydroxybenzoic acid synthase AAA_5 PF07728.14 PSC72582.1 - 9.7e-22 77.5 0.0 2.3e-21 76.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_8 PF17868.1 PSC72582.1 - 9.2e-21 73.5 0.1 1.7e-20 72.7 0.1 1.5 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase PF01078.21 PSC72582.1 - 0.0053 16.2 0.0 0.013 14.9 0.0 1.6 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 PSC72582.1 - 0.0059 16.5 0.0 0.0099 15.7 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PSC72582.1 - 1.5 9.2 8.4 0.26 11.7 1.0 3.1 2 1 0 2 2 2 0 AAA ATPase domain IRK_C PF17655.1 PSC72583.1 - 4.2e-45 153.5 0.0 6.7e-32 110.5 0.0 2.2 2 0 0 2 2 2 2 Inward rectifier potassium channel C-terminal domain IRK PF01007.20 PSC72583.1 - 2.5e-11 43.6 10.9 2.5e-10 40.3 10.9 2.0 1 1 0 1 1 1 1 Inward rectifier potassium channel transmembrane domain DUF4164 PF13747.6 PSC72583.1 - 0.071 13.4 0.5 0.16 12.3 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) PhnG PF06754.12 PSC72583.1 - 1.4 8.9 10.2 3.3 7.6 10.2 1.5 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG Suf PF05843.14 PSC72583.1 - 1.7 8.5 10.5 2.7 7.9 10.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 PSC72583.1 - 4.3 7.2 19.8 6.5 6.6 19.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 PSC72583.1 - 5.3 6.6 10.4 9.8 5.7 10.4 1.3 1 0 0 1 1 1 0 Spt20 family Ion_trans_2 PF07885.16 PSC72583.1 - 8.2 6.5 9.6 15 5.6 9.6 1.4 1 0 0 1 1 1 0 Ion channel Nucleotid_trans PF03407.16 PSC72584.1 - 8.2e-12 45.6 0.0 1.2e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Sigma70_r2 PF04542.14 PSC72585.1 - 2.5e-05 23.9 0.2 0.00013 21.7 0.1 2.3 1 1 0 1 1 1 1 Sigma-70 region 2 Sigma70_r4 PF04545.16 PSC72585.1 - 0.0061 16.1 0.8 0.0061 16.1 0.8 1.8 2 0 0 2 2 2 1 Sigma-70, region 4 SBP PF03110.14 PSC72586.1 - 1.2e-24 86.4 9.0 1.2e-24 86.4 9.0 2.9 2 0 0 2 2 2 1 SBP domain Draxin PF15550.6 PSC72586.1 - 0.13 12.1 29.0 0.015 15.2 16.4 2.4 2 0 0 2 2 2 0 Draxin SID-1_RNA_chan PF13965.6 PSC72586.1 - 1.7 7.0 10.1 3 6.1 10.1 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RIFIN PF02009.16 PSC72586.1 - 4.3 7.1 27.4 1.9 8.3 16.1 2.4 2 0 0 2 2 2 0 Rifin DUF4471 PF14740.6 PSC72586.1 - 6.8 5.8 18.5 0.23 10.6 11.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4471) RR_TM4-6 PF06459.12 PSC72586.1 - 8.6 6.1 41.8 0.46 10.3 25.2 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 NRDE-2 PF08424.10 PSC72589.1 - 2.1e-56 191.4 3.1 1.7e-55 188.4 0.1 3.5 4 1 0 4 4 4 1 NRDE-2, necessary for RNA interference DUF4614 PF15391.6 PSC72589.1 - 0.0011 19.0 0.6 0.0011 19.0 0.6 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4614) Acyl_transf_3 PF01757.22 PSC72591.1 - 9.9e-16 57.7 26.3 1.5e-15 57.1 26.3 1.2 1 0 0 1 1 1 1 Acyltransferase family Caerin_1 PF07440.12 PSC72591.1 - 0.1 12.7 1.6 0.29 11.3 1.6 1.8 1 0 0 1 1 1 0 Caerin 1 protein Pkinase PF00069.25 PSC72592.1 - 0.00012 21.5 0.0 0.0002 20.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC72592.1 - 0.054 12.8 0.0 0.08 12.2 0.0 1.2 1 0 0 1 1 1 0 Protein tyrosine kinase Na_H_Exchanger PF00999.21 PSC72593.1 - 2.6e-56 191.0 48.5 4.5e-56 190.3 48.5 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Na_H_Exchanger PF00999.21 PSC72594.1 - 2.8e-56 191.0 48.5 4.8e-56 190.2 48.5 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Cdh1_DBD_1 PF18196.1 PSC72595.1 - 0.12 12.7 3.3 0.13 12.6 3.3 1.2 1 0 0 1 1 1 0 Chromodomain helicase DNA-binding domain 1 DUF4175 PF13779.6 PSC72595.1 - 0.15 9.9 14.8 0.16 9.9 14.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Coilin_N PF15862.5 PSC72595.1 - 0.28 11.0 5.0 0.36 10.6 5.0 1.1 1 0 0 1 1 1 0 Coilin N-terminus CN_hydrolase PF00795.22 PSC72596.1 - 2.8e-19 69.5 0.0 2.4e-14 53.3 0.1 2.7 1 1 1 2 2 2 2 Carbon-nitrogen hydrolase TPR_MLP1_2 PF07926.12 PSC72596.1 - 0.0028 17.7 30.5 0.0028 17.7 30.5 8.2 4 1 5 9 9 9 3 TPR/MLP1/MLP2-like protein Spc7 PF08317.11 PSC72596.1 - 6.2 5.6 95.7 0.17 10.7 11.2 5.7 2 1 4 6 6 6 0 Spc7 kinetochore protein PTA_PTB PF01515.19 PSC72597.1 - 1.9e-115 385.6 1.9 1.9e-115 385.6 1.9 1.5 2 0 0 2 2 2 1 Phosphate acetyl/butaryl transferase AAA_26 PF13500.6 PSC72597.1 - 7e-16 58.6 0.0 1.3e-15 57.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain DRTGG PF07085.12 PSC72597.1 - 1e-05 25.3 0.0 4e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 DRTGG domain CbiA PF01656.23 PSC72597.1 - 0.062 13.4 0.0 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain TRAPPC10 PF12584.8 PSC72598.1 - 6.8e-06 25.9 0.0 1.4e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 PSC72598.1 - 0.025 14.2 1.2 0.061 12.9 1.2 1.6 1 0 0 1 1 1 0 Foie gras liver health family 1 Trs65 PF12735.7 PSC72598.1 - 0.26 10.7 0.0 0.66 9.3 0.0 1.6 1 0 0 1 1 1 0 TRAPP trafficking subunit Trs65 SNAP PF14938.6 PSC72598.1 - 0.99 8.8 4.9 0.16 11.3 1.1 1.6 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP SUIM_assoc PF16619.5 PSC72598.1 - 2.6 8.2 8.1 11 6.1 8.1 2.1 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DEAD PF00270.29 PSC72599.1 - 5.2e-41 140.3 0.0 7.6e-41 139.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase MIP PF00230.20 PSC72599.1 - 6.2e-27 94.8 9.5 2.2e-13 50.5 2.1 2.2 2 0 0 2 2 2 2 Major intrinsic protein Helicase_C PF00271.31 PSC72599.1 - 1.2e-26 93.2 0.0 3.7e-26 91.6 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC72599.1 - 5.3e-05 23.3 0.0 8.4e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DUF3493 PF11998.8 PSC72600.1 - 6.4e-20 71.1 0.4 1.5e-19 70.0 0.4 1.6 1 0 0 1 1 1 1 Low psii accumulation1 / Rep27 MauJ PF17419.2 PSC72600.1 - 0.073 12.5 0.9 0.13 11.7 0.9 1.4 1 0 0 1 1 1 0 Methylamine utilization protein MauJ MFS_1 PF07690.16 PSC72601.1 - 2.2e-26 92.7 36.1 2.1e-19 69.6 8.0 2.9 3 1 0 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PSC72601.1 - 0.00037 19.5 6.6 0.025 13.5 0.1 2.8 2 1 1 3 3 3 3 Sugar (and other) transporter OATP PF03137.20 PSC72601.1 - 0.0028 16.0 0.1 0.068 11.4 0.1 2.1 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family TRI12 PF06609.13 PSC72601.1 - 0.0032 16.0 0.7 0.005 15.3 0.7 1.2 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) NCA2 PF08637.10 PSC72602.1 - 3.4e-45 154.4 0.0 6.3e-45 153.6 0.0 1.4 1 0 0 1 1 1 1 ATP synthase regulation protein NCA2 Auxin_BP PF02041.16 PSC72602.1 - 1.5e-20 73.5 0.0 2.7e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Auxin binding protein zf-C3HC4 PF00097.25 PSC72602.1 - 1.2e-05 25.1 1.0 2.2e-05 24.3 1.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Cupin_2 PF07883.11 PSC72602.1 - 1.9e-05 24.3 0.0 3.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Cupin domain zf-RING_2 PF13639.6 PSC72602.1 - 2.3e-05 24.6 3.3 2.3e-05 24.6 3.3 1.9 2 0 0 2 2 1 1 Ring finger domain AraC_binding PF02311.19 PSC72602.1 - 0.0024 17.8 0.0 0.0074 16.2 0.0 1.8 1 0 0 1 1 1 1 AraC-like ligand binding domain ARD PF03079.14 PSC72602.1 - 0.0027 17.9 0.0 0.005 17.0 0.0 1.4 1 0 0 1 1 1 1 ARD/ARD' family zf-RING_11 PF17123.5 PSC72602.1 - 0.0059 16.3 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PSC72602.1 - 0.022 14.6 0.7 0.022 14.6 0.7 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GPI PF06560.11 PSC72602.1 - 0.039 13.2 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 Glucose-6-phosphate isomerase (GPI) Cupin_1 PF00190.22 PSC72602.1 - 0.04 13.5 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Cupin PPR_2 PF13041.6 PSC72603.1 - 2.9e-60 200.3 0.0 1.4e-09 38.0 0.0 14.1 9 3 5 14 14 14 10 PPR repeat family PPR_3 PF13812.6 PSC72603.1 - 5.9e-45 151.2 0.0 7.2e-09 35.6 0.0 9.4 8 1 2 10 10 10 7 Pentatricopeptide repeat domain PPR PF01535.20 PSC72603.1 - 3.2e-39 130.5 12.0 0.0051 17.0 0.0 16.5 15 2 0 15 15 15 12 PPR repeat PPR_1 PF12854.7 PSC72603.1 - 1.9e-31 107.4 11.7 0.00038 20.1 0.0 15.0 14 2 0 14 14 14 8 PPR repeat PPR_long PF17177.4 PSC72603.1 - 5e-27 94.7 4.8 5.3e-09 35.8 0.0 6.5 3 2 2 6 6 6 4 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 PSC72603.1 - 0.00022 21.6 20.5 0.35 11.4 0.0 7.3 6 1 1 7 7 7 2 Tetratricopeptide repeat ATP13 PF12921.7 PSC72603.1 - 0.022 14.6 0.0 0.92 9.4 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial ATPase expression Sel1 PF08238.12 PSC72603.1 - 0.024 15.3 0.0 0.14 12.9 0.0 2.4 1 0 0 1 1 1 0 Sel1 repeat PPR_2 PF13041.6 PSC72604.1 - 5e-61 202.7 0.0 1.4e-09 38.0 0.0 14.4 8 4 7 15 15 15 11 PPR repeat family PPR_3 PF13812.6 PSC72604.1 - 3.3e-45 152.0 0.0 7.3e-09 35.6 0.0 9.4 8 1 2 10 10 10 8 Pentatricopeptide repeat domain PPR PF01535.20 PSC72604.1 - 2.6e-43 143.3 11.8 0.0052 16.9 0.0 16.5 15 2 0 15 15 15 12 PPR repeat PPR_1 PF12854.7 PSC72604.1 - 2.6e-34 116.6 11.7 0.00038 20.1 0.0 15.0 14 2 0 14 14 14 9 PPR repeat PPR_long PF17177.4 PSC72604.1 - 3.2e-29 101.8 4.3 5.4e-09 35.7 0.0 6.8 3 2 2 6 6 6 4 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 PSC72604.1 - 2.1e-05 24.9 22.9 0.35 11.4 0.0 7.6 6 1 1 7 7 7 2 Tetratricopeptide repeat Sel1 PF08238.12 PSC72604.1 - 0.023 15.4 0.0 0.14 12.9 0.0 2.5 1 0 0 1 1 1 0 Sel1 repeat ATP13 PF12921.7 PSC72604.1 - 0.023 14.5 0.0 0.94 9.4 0.0 3.0 3 0 0 3 3 3 0 Mitochondrial ATPase expression SPOR PF05036.13 PSC72604.1 - 0.12 12.7 2.4 5.9 7.3 0.2 4.2 4 0 0 4 4 4 0 Sporulation related domain Sec10 PF07393.11 PSC72605.1 - 4.9e-81 273.2 0.0 4.1e-41 141.2 0.0 3.0 1 1 1 2 2 2 2 Exocyst complex component Sec10 UDPG_MGDP_dh_N PF03721.14 PSC72605.1 - 0.23 11.0 0.0 1.9 8.0 0.0 2.1 1 1 1 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF2057 PF09829.9 PSC72605.1 - 3 8.0 12.5 3.2 7.9 4.6 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) TFIIA PF03153.13 PSC72605.1 - 3 7.7 5.8 6.1 6.7 5.8 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ldh_1_C PF02866.18 PSC72606.1 - 5.1e-44 150.1 0.0 7.9e-44 149.5 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 PSC72606.1 - 4.3e-42 143.6 0.0 6.1e-42 143.0 0.0 1.2 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain 3Beta_HSD PF01073.19 PSC72606.1 - 0.00099 18.2 0.0 0.0014 17.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Semialdhyde_dh PF01118.24 PSC72606.1 - 0.17 12.3 0.4 0.72 10.3 0.1 2.0 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DUF3551 PF12071.8 PSC72606.1 - 0.28 11.3 2.1 0.58 10.3 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3551) Ribosomal_L7Ae PF01248.26 PSC72607.1 - 1.5e-22 79.1 2.1 8.9e-22 76.7 0.4 2.1 2 0 0 2 2 2 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF4710 PF15828.5 PSC72607.1 - 0.026 14.6 1.1 0.026 14.6 1.1 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4710) Glyco_hydro_9 PF00759.19 PSC72607.1 - 0.031 13.7 2.3 0.039 13.4 2.3 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 9 SR-25 PF10500.9 PSC72607.1 - 0.067 12.8 5.6 0.094 12.3 5.6 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DNA_pol_A_exo1 PF01612.20 PSC72608.1 - 3.8e-17 62.6 0.0 8.5e-17 61.4 0.0 1.5 1 1 0 1 1 1 1 3'-5' exonuclease AAA PF00004.29 PSC72608.1 - 1.6e-07 31.8 0.0 3.5e-07 30.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PSC72608.1 - 1.1e-06 28.7 0.0 1.2e-05 25.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 PSC72608.1 - 3.1e-06 27.1 0.2 3.1e-06 27.1 0.2 2.7 3 0 0 3 3 2 1 AAA domain Mg_chelatase PF01078.21 PSC72608.1 - 2.1e-05 24.0 0.1 4.2e-05 23.0 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 PSC72608.1 - 2.6e-05 24.6 0.3 0.00054 20.4 0.0 3.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_19 PF13245.6 PSC72608.1 - 0.00023 21.5 0.1 0.0011 19.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 PSC72608.1 - 0.00033 20.6 1.2 0.24 11.3 0.1 2.5 1 1 1 2 2 2 2 NTPase T2SSE PF00437.20 PSC72608.1 - 0.0011 18.1 0.4 0.002 17.2 0.4 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_18 PF13238.6 PSC72608.1 - 0.0012 19.4 0.0 0.0024 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 PSC72608.1 - 0.0018 18.3 0.0 0.0032 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 PSC72608.1 - 0.0026 18.0 0.0 0.0072 16.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PSC72608.1 - 0.0031 17.8 0.0 0.0085 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 PSC72608.1 - 0.0043 16.8 0.0 0.0066 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 PSC72608.1 - 0.0056 16.6 0.0 0.049 13.6 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.6 PSC72608.1 - 0.0099 16.3 0.0 0.14 12.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 PSC72608.1 - 0.015 15.1 0.0 0.026 14.3 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase SRP54 PF00448.22 PSC72608.1 - 0.015 14.9 0.0 0.061 12.9 0.0 1.9 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain KdpD PF02702.17 PSC72608.1 - 0.015 14.7 0.1 0.028 13.9 0.1 1.3 1 0 0 1 1 1 0 Osmosensitive K+ channel His kinase sensor domain TniB PF05621.11 PSC72608.1 - 0.039 13.4 0.0 0.11 11.8 0.0 1.8 1 1 0 1 1 1 0 Bacterial TniB protein AAA_11 PF13086.6 PSC72608.1 - 0.042 13.6 0.2 5.2 6.8 0.1 2.3 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 PSC72608.1 - 0.06 13.5 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 AAA domain CbiA PF01656.23 PSC72608.1 - 0.14 12.2 0.0 0.37 10.8 0.0 1.7 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 PSC72608.1 - 0.2 11.4 0.0 0.36 10.6 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein BRCT PF00533.26 PSC72609.1 - 3.6e-05 24.1 0.0 5.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PSC72609.1 - 7.4e-05 23.1 0.0 0.00018 21.8 0.0 1.7 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BAH PF01426.18 PSC72609.1 - 0.0011 18.8 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 BAH domain RTT107_BRCT_5 PF16770.5 PSC72609.1 - 0.075 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 PSC72610.1 - 3.6e-05 24.1 0.0 5.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PSC72610.1 - 7.4e-05 23.1 0.0 0.00018 21.8 0.0 1.7 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain BAH PF01426.18 PSC72610.1 - 0.0011 18.8 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 BAH domain RTT107_BRCT_5 PF16770.5 PSC72610.1 - 0.074 12.9 0.0 0.17 11.7 0.0 1.6 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Complex1_LYR PF05347.15 PSC72611.1 - 9.3e-13 48.0 0.2 1.3e-12 47.5 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 PSC72611.1 - 0.027 15.2 0.4 0.032 15.0 0.4 1.2 1 0 0 1 1 1 0 Complex1_LYR-like MT-A70 PF05063.14 PSC72612.1 - 4.4e-37 127.6 0.0 6.6e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 MT-A70 AKAP7_NLS PF10469.9 PSC72612.1 - 1.2e-23 84.1 0.0 4.7e-21 75.6 0.0 2.4 2 0 0 2 2 2 2 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 PSC72612.1 - 3.3e-08 33.6 0.1 7.8e-08 32.4 0.1 1.7 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 PSC72612.1 - 9.1e-05 22.6 1.3 0.09 13.0 0.1 3.4 3 0 0 3 3 3 2 LigT like Phosphoesterase HD_3 PF13023.6 PSC72613.1 - 0.0029 17.6 2.3 0.0049 16.8 2.3 1.3 1 0 0 1 1 1 1 HD domain DUF812 PF05667.11 PSC72613.1 - 0.11 11.3 5.6 0.21 10.4 5.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF3614 PF12267.8 PSC72613.1 - 1.2 9.6 6.6 0.46 11.0 3.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3614) APG6 PF04111.12 PSC72614.1 - 5.5e-48 163.3 0.0 7.6e-48 162.8 0.0 1.2 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 PSC72614.1 - 1e-16 61.7 12.0 1.4e-16 61.3 12.0 1.2 1 0 0 1 1 1 1 Apg6 coiled-coil region DUF4407 PF14362.6 PSC72614.1 - 0.00026 20.4 2.3 0.00039 19.9 2.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) FapA PF03961.13 PSC72614.1 - 0.035 12.7 0.2 0.047 12.3 0.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A Lebercilin PF15619.6 PSC72614.1 - 0.11 12.1 7.2 0.06 13.0 4.8 1.6 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease PilJ PF13675.6 PSC72614.1 - 0.16 12.0 5.1 0.09 12.8 2.1 2.1 2 0 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term OmpH PF03938.14 PSC72614.1 - 0.47 10.8 3.7 0.73 10.2 3.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Uso1_p115_C PF04871.13 PSC72614.1 - 0.56 10.6 7.6 0.87 10.0 7.6 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Spc7 PF08317.11 PSC72614.1 - 0.68 8.8 5.8 1 8.2 5.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4719 PF15843.5 PSC72614.1 - 0.69 10.0 6.4 1.7 8.7 6.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) HAUS-augmin3 PF14932.6 PSC72614.1 - 1.3 8.6 7.7 1.1 8.8 6.3 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 CENP-Q PF13094.6 PSC72614.1 - 1.4 9.1 8.2 2.2 8.4 8.2 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF4140 PF13600.6 PSC72614.1 - 1.5 9.3 11.4 0.93 10.0 1.5 3.1 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF4226 PF10774.9 PSC72614.1 - 1.6 9.0 7.1 2.2 8.6 4.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4226) FPP PF05911.11 PSC72614.1 - 1.7 6.7 6.4 2.4 6.2 6.4 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil HR1 PF02185.16 PSC72614.1 - 2.7 8.2 6.2 10 6.4 0.3 2.4 2 0 0 2 2 2 0 Hr1 repeat Mito_carr PF00153.27 PSC72619.1 - 3.6e-40 135.8 1.9 7.1e-15 54.7 0.5 3.3 3 0 0 3 3 3 3 Mitochondrial carrier protein JHY PF15261.6 PSC72620.1 - 9.7e-06 26.3 0.3 9.7e-06 26.3 0.3 1.6 2 0 0 2 2 2 1 Jhy protein HHH_5 PF14520.6 PSC72622.1 - 0.0025 18.4 0.2 0.0052 17.4 0.2 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain Cdd1 PF11731.8 PSC72622.1 - 0.018 15.3 0.0 0.029 14.6 0.0 1.3 1 0 0 1 1 1 0 Pathogenicity locus DNA_pol_lambd_f PF10391.9 PSC72622.1 - 0.076 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Fingers domain of DNA polymerase lambda Totivirus_coat PF05518.11 PSC72622.1 - 3.6 5.5 7.9 5 5.0 7.9 1.2 1 0 0 1 1 1 0 Totivirus coat protein DEAD PF00270.29 PSC72623.1 - 2e-46 158.0 0.0 3.9e-46 157.0 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC72623.1 - 5.2e-33 113.7 0.0 4.6e-32 110.7 0.0 2.1 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC72623.1 - 0.005 16.9 0.0 0.0081 16.2 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 PSC72623.1 - 0.21 11.9 0.0 28 5.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNase_T PF00929.24 PSC72624.1 - 5.4e-28 98.6 0.0 6.1e-28 98.4 0.0 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 PSC72624.1 - 7.7e-07 29.2 0.0 1e-06 28.8 0.0 1.0 1 0 0 1 1 1 1 3' exoribonuclease, RNase T-like Lactamase_B PF00753.27 PSC72625.1 - 0.0005 20.1 1.1 0.0015 18.5 1.1 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Kelch_4 PF13418.6 PSC72626.1 - 2e-42 143.0 1.2 6.8e-08 32.4 0.0 7.4 2 1 4 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 PSC72626.1 - 2.7e-34 116.3 2.4 1.4e-08 34.7 0.0 7.2 5 1 1 6 6 6 5 Kelch motif Kelch_3 PF13415.6 PSC72626.1 - 1.4e-29 101.7 6.8 1.7e-05 25.0 0.2 8.6 8 1 0 8 8 8 5 Galactose oxidase, central domain Kelch_5 PF13854.6 PSC72626.1 - 4.6e-26 90.3 0.0 0.00016 21.5 0.0 6.9 6 1 0 6 6 6 6 Kelch motif Kelch_1 PF01344.25 PSC72626.1 - 2.5e-17 62.2 1.7 1.4e-05 24.6 0.0 6.9 6 1 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 PSC72626.1 - 2.2e-15 55.9 6.9 7.4e-05 22.6 0.1 6.1 6 1 0 6 6 6 3 Kelch motif IQ PF00612.27 PSC72626.1 - 5.8e-05 22.5 1.2 0.00012 21.6 1.2 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif FYTT PF07078.11 PSC72627.1 - 0.023 14.1 0.2 0.032 13.6 0.2 1.2 1 0 0 1 1 1 0 Forty-two-three protein DUF2807 PF10988.8 PSC72628.1 - 2.2e-06 27.6 0.5 4.7e-06 26.5 0.0 1.8 1 1 1 2 2 2 1 Putative auto-transporter adhesin, head GIN domain Carcinustatin PF08261.12 PSC72628.1 - 0.55 11.0 3.1 56 5.0 0.7 3.5 2 0 0 2 2 2 0 Carcinustatin peptide U3_snoRNA_assoc PF08297.11 PSC72629.1 - 0.14 12.9 0.1 0.14 12.9 0.1 4.2 3 1 0 3 3 3 0 U3 snoRNA associated DNA_pol_phi PF04931.13 PSC72629.1 - 0.8 7.7 10.7 1.4 7.0 10.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi EMP70 PF02990.16 PSC72630.1 - 2e-175 584.4 8.1 2.5e-175 584.1 8.1 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 TMEM190 PF15431.6 PSC72630.1 - 0.36 11.0 2.6 1.1 9.4 2.6 1.9 1 0 0 1 1 1 0 Transmembrane protein 190 Frag1 PF10277.9 PSC72630.1 - 2.3 7.7 33.1 9.1e+02 -0.8 33.1 2.8 1 1 0 1 1 1 0 Frag1/DRAM/Sfk1 family ARTD15_N PF18084.1 PSC72631.1 - 4.7e-15 55.6 0.8 2e-14 53.6 0.2 2.5 2 0 0 2 2 2 1 ARTD15 N-terminal domain PARP PF00644.20 PSC72631.1 - 1.6e-12 47.4 0.0 2.8e-12 46.7 0.0 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain LRR_4 PF12799.7 PSC72631.1 - 4.1e-07 30.2 6.2 0.0056 17.1 0.0 5.5 4 1 2 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC72631.1 - 1.5e-06 27.9 9.7 2.6e-06 27.1 0.1 3.8 4 0 0 4 4 4 2 Leucine rich repeat F-box PF00646.33 PSC72631.1 - 1.7e-05 24.6 0.2 4.6e-05 23.2 0.2 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PSC72631.1 - 0.00013 21.8 1.1 0.00013 21.8 1.1 2.0 2 0 0 2 2 2 1 F-box-like LRR_1 PF00560.33 PSC72631.1 - 0.0013 19.0 2.7 4.8 8.1 0.0 5.1 5 0 0 5 5 5 1 Leucine Rich Repeat Lactamase_B_2 PF12706.7 PSC72632.1 - 7.5e-08 32.1 0.1 1.3e-07 31.4 0.1 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PSC72632.1 - 1.6e-06 28.3 0.8 1.6e-06 28.3 0.8 2.1 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily HEPN_Apea PF18739.1 PSC72633.1 - 0.058 13.8 0.2 0.078 13.4 0.2 1.3 1 1 0 1 1 1 0 Apea-like HEPN Metallophos PF00149.28 PSC72636.1 - 8.2e-22 78.7 0.0 1.4e-21 77.9 0.0 1.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Pkinase_Tyr PF07714.17 PSC72637.1 - 4.8e-49 167.0 0.0 6.3e-40 137.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PSC72637.1 - 7.3e-44 150.1 0.0 1.3e-35 123.1 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain APH PF01636.23 PSC72637.1 - 0.041 13.8 0.1 0.041 13.8 0.1 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family Nitrate_red_gam PF02665.14 PSC72637.1 - 0.098 12.2 0.1 0.29 10.7 0.1 1.7 2 0 0 2 2 2 0 Nitrate reductase gamma subunit RRM_1 PF00076.22 PSC72638.1 - 3.5e-11 42.8 0.0 1.4e-05 24.8 0.1 4.1 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LysM PF01476.20 PSC72639.1 - 6.6e-10 38.9 0.1 1e-09 38.3 0.1 1.3 1 0 0 1 1 1 1 LysM domain THUMP PF02926.17 PSC72640.1 - 8.4e-11 42.2 0.0 1.8e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 THUMP domain SelK_SelG PF10961.8 PSC72640.1 - 1.1 10.0 0.1 1.1 10.0 0.1 2.5 2 0 0 2 2 2 0 Selenoprotein SelK_SelG COQ9 PF08511.11 PSC72641.1 - 1.1e-28 98.8 0.4 1.9e-28 98.0 0.4 1.4 1 0 0 1 1 1 1 COQ9 Pectate_lyase_3 PF12708.7 PSC72641.1 - 4.6e-09 36.4 0.1 7.9e-09 35.7 0.1 1.3 1 0 0 1 1 1 1 Pectate lyase superfamily protein Pectinesterase PF01095.19 PSC72641.1 - 0.076 11.7 0.0 0.12 11.0 0.0 1.2 1 0 0 1 1 1 0 Pectinesterase Arf PF00025.21 PSC72642.1 - 8.5e-63 210.9 0.0 2.3e-62 209.5 0.0 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Uricase PF01014.18 PSC72642.1 - 1.7e-44 151.3 1.0 3e-24 85.8 1.0 2.3 2 0 0 2 2 2 2 Uricase PhyH PF05721.13 PSC72642.1 - 2.8e-17 63.7 0.0 6.9e-17 62.4 0.0 1.7 1 1 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) G-alpha PF00503.20 PSC72642.1 - 7e-09 35.3 0.1 9.7e-06 25.0 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Roc PF08477.13 PSC72642.1 - 2.6e-08 34.1 0.0 6e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 PSC72642.1 - 9.3e-08 31.7 0.0 2e-07 30.6 0.0 1.5 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Ras PF00071.22 PSC72642.1 - 3.2e-07 30.1 0.0 5.1e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 PSC72642.1 - 1.3e-06 28.4 0.0 2.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PSC72642.1 - 0.01 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 PSC72642.1 - 0.014 15.1 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Nop52 PF05997.12 PSC72643.1 - 1.3e-54 185.3 0.0 2.1e-54 184.6 0.0 1.3 1 0 0 1 1 1 1 Nucleolar protein,Nop52 zf-RING_UBOX PF13445.6 PSC72643.1 - 0.00039 20.4 0.4 0.00077 19.4 0.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PSC72643.1 - 0.018 15.2 0.3 0.032 14.4 0.3 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 PSC72643.1 - 0.041 13.7 0.3 0.079 12.8 0.3 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC72643.1 - 0.067 13.1 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC72643.1 - 0.13 12.1 0.2 0.23 11.4 0.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.13 PSC72643.1 - 0.78 9.7 17.5 0.062 13.3 12.9 1.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pneumo_att_G PF05539.11 PSC72643.1 - 2.8 7.5 6.4 5.5 6.5 6.4 1.4 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G VSP PF03302.13 PSC72644.1 - 3 6.6 143.6 0.24 10.2 25.8 5.3 1 1 4 5 5 5 0 Giardia variant-specific surface protein Bap31 PF05529.12 PSC72645.1 - 2.3e-10 40.4 1.1 2.8e-10 40.2 1.1 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region TMEM237 PF15383.6 PSC72645.1 - 0.025 13.7 1.3 0.036 13.2 1.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 237 Bap31 PF05529.12 PSC72646.1 - 2.3e-10 40.4 1.1 2.8e-10 40.2 1.1 1.1 1 0 0 1 1 1 1 Bap31/Bap29 transmembrane region TMEM237 PF15383.6 PSC72646.1 - 0.025 13.7 1.3 0.036 13.2 1.3 1.1 1 0 0 1 1 1 0 Transmembrane protein 237 Abhydrolase_6 PF12697.7 PSC72647.1 - 1.3e-14 55.4 0.3 1.3e-14 55.4 0.3 1.3 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PSC72647.1 - 9e-11 41.9 0.1 1.4e-09 38.0 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC72647.1 - 1.6e-10 40.7 0.0 2.2e-10 40.2 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 ABC2_membrane PF01061.24 PSC72648.1 - 4.1e-35 121.1 0.2 5.4e-35 120.7 0.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PSC72648.1 - 6.3e-23 81.8 0.0 1.1e-22 81.0 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PSC72648.1 - 1.4e-06 27.7 0.3 2e-06 27.2 0.3 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PSC72648.1 - 4.5e-05 23.4 0.0 0.021 14.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PSC72648.1 - 0.00044 20.7 0.0 0.00092 19.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 PSC72648.1 - 0.00057 19.4 0.0 0.3 10.5 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PSC72648.1 - 0.0018 18.0 0.5 0.0042 16.8 0.5 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 PSC72648.1 - 0.0026 18.3 0.2 0.0044 17.6 0.2 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 PSC72648.1 - 0.0036 17.2 0.0 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 PSC72648.1 - 0.0075 15.9 0.1 0.015 14.9 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PSC72648.1 - 0.016 15.4 0.0 0.049 13.9 0.0 1.7 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 PSC72648.1 - 0.02 15.1 0.4 0.045 14.0 0.1 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 PSC72648.1 - 0.026 14.7 0.0 0.05 13.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PSC72648.1 - 0.049 14.2 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 PSC72648.1 - 0.085 12.6 0.1 0.085 12.6 0.1 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 PSC72648.1 - 0.1 12.5 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 PSC72648.1 - 0.12 11.9 0.1 0.2 11.2 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 PSC72648.1 - 0.18 12.2 0.0 0.34 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_ATPase PF09818.9 PSC72648.1 - 0.24 10.2 0.2 0.37 9.5 0.2 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_24 PF13479.6 PSC72648.1 - 0.26 11.0 0.1 0.55 9.9 0.1 1.4 1 0 0 1 1 1 0 AAA domain ABC2_membrane PF01061.24 PSC72649.1 - 3.9e-35 121.2 0.2 5.2e-35 120.8 0.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PSC72649.1 - 2.2e-24 86.5 0.0 3.6e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PSC72649.1 - 1.3e-06 27.8 0.3 2e-06 27.2 0.3 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PSC72649.1 - 3.4e-05 23.8 0.2 0.018 14.9 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PSC72649.1 - 0.00013 22.4 0.0 0.00028 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 PSC72649.1 - 0.00041 19.9 0.0 0.0039 16.6 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PSC72649.1 - 0.0015 18.2 0.3 0.0035 17.1 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 PSC72649.1 - 0.002 18.7 0.0 0.0041 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 PSC72649.1 - 0.0024 18.4 0.1 0.0039 17.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 PSC72649.1 - 0.0043 17.0 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 PSC72649.1 - 0.0067 16.0 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PSC72649.1 - 0.017 15.4 0.1 0.05 13.9 0.1 1.7 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 PSC72649.1 - 0.028 14.6 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PSC72649.1 - 0.032 14.5 1.2 0.045 14.0 0.2 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 PSC72649.1 - 0.06 13.1 0.1 0.06 13.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 PSC72649.1 - 0.1 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 PSC72649.1 - 0.12 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 PSC72649.1 - 0.12 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 PSC72649.1 - 0.18 11.7 0.3 0.52 10.2 0.0 1.9 3 0 0 3 3 2 0 NTPase ABC_ATPase PF09818.9 PSC72649.1 - 0.23 10.2 0.2 0.37 9.5 0.2 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Rad17 PF03215.15 PSC72649.1 - 0.25 11.3 0.0 0.4 10.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain ABC2_membrane PF01061.24 PSC72650.1 - 3.9e-35 121.2 0.2 5.2e-35 120.8 0.2 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PSC72650.1 - 2.2e-24 86.5 0.0 3.6e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PSC72650.1 - 1.3e-06 27.8 0.3 2e-06 27.2 0.3 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PSC72650.1 - 3.4e-05 23.8 0.2 0.018 14.9 0.1 2.2 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PSC72650.1 - 0.00013 22.4 0.0 0.00028 21.3 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.19 PSC72650.1 - 0.00041 19.9 0.0 0.0039 16.6 0.0 2.1 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PSC72650.1 - 0.0015 18.2 0.3 0.0035 17.1 0.3 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_18 PF13238.6 PSC72650.1 - 0.002 18.7 0.0 0.0041 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 PSC72650.1 - 0.0024 18.4 0.1 0.0039 17.7 0.1 1.2 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 PSC72650.1 - 0.0043 17.0 0.0 0.0084 16.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 PSC72650.1 - 0.0067 16.0 0.1 0.013 15.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PSC72650.1 - 0.017 15.4 0.1 0.05 13.9 0.1 1.7 2 0 0 2 2 1 0 AAA domain AAA_33 PF13671.6 PSC72650.1 - 0.028 14.6 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PSC72650.1 - 0.032 14.5 1.2 0.045 14.0 0.2 1.7 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 PSC72650.1 - 0.06 13.1 0.1 0.06 13.1 0.1 1.9 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 PSC72650.1 - 0.1 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 PSC72650.1 - 0.12 12.0 0.1 0.19 11.3 0.1 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 PSC72650.1 - 0.12 12.8 0.0 0.22 11.9 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 PSC72650.1 - 0.18 11.7 0.3 0.52 10.2 0.0 1.9 3 0 0 3 3 2 0 NTPase ABC_ATPase PF09818.9 PSC72650.1 - 0.23 10.2 0.2 0.37 9.5 0.2 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class Rad17 PF03215.15 PSC72650.1 - 0.25 11.3 0.0 0.4 10.6 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain Tocopherol_cycl PF14249.6 PSC72651.1 - 3.6e-136 453.7 0.8 4.6e-136 453.4 0.8 1.1 1 0 0 1 1 1 1 Tocopherol cyclase Ank_2 PF12796.7 PSC72651.1 - 1.2e-13 51.5 4.0 1.2e-08 35.4 0.9 2.5 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC72651.1 - 6.6e-13 48.6 11.0 2.3e-07 30.9 0.5 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC72651.1 - 1e-10 41.9 7.1 3.4e-05 24.3 0.5 3.8 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 PSC72651.1 - 5.4e-10 39.3 13.1 0.0014 18.9 0.2 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 PSC72651.1 - 2.7e-08 33.4 9.1 0.24 12.1 0.1 5.6 5 0 0 5 5 5 3 Ankyrin repeat Chloroa_b-bind PF00504.21 PSC72652.1 - 1.1e-43 149.6 0.1 1.4e-43 149.2 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein fn3 PF00041.21 PSC72653.1 - 0.00017 21.9 2.6 0.0044 17.3 0.1 3.5 3 1 0 3 3 3 1 Fibronectin type III domain AAA_12 PF13087.6 PSC72654.1 - 1.9e-41 141.9 0.0 2.9e-41 141.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PSC72654.1 - 3.8e-28 99.0 5.5 1.5e-24 87.2 0.0 3.3 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 PSC72654.1 - 1.4e-10 41.3 0.0 0.018 14.8 0.0 3.4 3 0 0 3 3 3 3 Viral (Superfamily 1) RNA helicase PLAC8 PF04749.17 PSC72654.1 - 1.1e-09 39.2 0.7 4.7e-09 37.2 0.7 2.2 1 0 0 1 1 1 1 PLAC8 family AAA_19 PF13245.6 PSC72654.1 - 1.8e-05 25.1 0.0 0.00012 22.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PSC72654.1 - 2.3e-05 24.9 0.5 2.3e-05 24.9 0.5 3.9 4 0 0 4 4 4 1 AAA ATPase domain UvrD_C_2 PF13538.6 PSC72654.1 - 0.00012 21.9 0.4 0.00044 20.0 0.1 2.2 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_29 PF13555.6 PSC72654.1 - 0.043 13.6 0.0 0.099 12.4 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.23 PSC72654.1 - 0.044 13.8 0.1 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Dynamin family CCDC53 PF10152.9 PSC72654.1 - 0.083 13.3 5.2 5.1 7.5 2.3 3.4 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex AAA_22 PF13401.6 PSC72654.1 - 0.092 13.0 0.0 0.26 11.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain cobW PF02492.19 PSC72654.1 - 0.2 11.2 0.0 0.41 10.2 0.0 1.5 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Presenilin PF01080.17 PSC72654.1 - 0.26 10.0 1.6 0.41 9.4 1.6 1.2 1 0 0 1 1 1 0 Presenilin ARS2 PF04959.13 PSC72654.1 - 0.3 11.5 0.0 0.3 11.5 0.0 3.4 4 0 0 4 4 2 0 Arsenite-resistance protein 2 AAA_23 PF13476.6 PSC72654.1 - 0.31 11.5 4.6 1.6 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain PBP_N PF17093.5 PSC72654.1 - 3.4 7.9 14.1 0.022 15.0 4.1 2.5 2 0 0 2 2 1 0 Penicillin-binding protein N-terminus Peptidase_S9 PF00326.21 PSC72655.1 - 3.3e-60 203.2 0.0 5.9e-60 202.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 PSC72655.1 - 1.1e-46 159.5 0.0 6.7e-34 117.4 0.0 3.1 3 0 0 3 3 3 3 Prolyl oligopeptidase, N-terminal beta-propeller domain IMS PF00817.20 PSC72655.1 - 1e-24 87.2 0.1 2e-24 86.3 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family Hydrolase_4 PF12146.8 PSC72655.1 - 4.9e-05 22.7 0.0 0.0001 21.7 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 PSC72655.1 - 0.002 17.8 3.9 0.0025 17.5 0.0 2.9 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 PSC72655.1 - 0.015 14.9 0.0 0.015 14.9 0.0 1.8 2 0 0 2 2 2 0 Putative esterase Peptidase_S9 PF00326.21 PSC72656.1 - 3.2e-60 203.2 0.0 5.8e-60 202.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 PSC72656.1 - 1.1e-46 159.5 0.0 6.7e-34 117.4 0.0 3.1 3 0 0 3 3 3 3 Prolyl oligopeptidase, N-terminal beta-propeller domain IMS PF00817.20 PSC72656.1 - 1e-24 87.2 0.1 2e-24 86.3 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family Hydrolase_4 PF12146.8 PSC72656.1 - 4.8e-05 22.7 0.0 0.0001 21.7 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 PSC72656.1 - 0.0021 17.7 4.0 0.0025 17.5 0.0 2.9 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 PSC72656.1 - 0.015 14.9 0.0 0.015 14.9 0.0 1.8 2 0 0 2 2 2 0 Putative esterase Peptidase_S9 PF00326.21 PSC72657.1 - 3.2e-60 203.2 0.0 5.8e-60 202.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 PSC72657.1 - 4.9e-51 173.8 0.0 2.7e-40 138.5 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase, N-terminal beta-propeller domain IMS PF00817.20 PSC72657.1 - 1e-24 87.2 0.1 2e-24 86.3 0.1 1.5 1 0 0 1 1 1 1 impB/mucB/samB family Hydrolase_4 PF12146.8 PSC72657.1 - 4.8e-05 22.7 0.0 0.0001 21.7 0.0 1.5 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 PSC72657.1 - 0.002 17.8 4.0 0.0024 17.5 0.0 3.0 3 0 0 3 3 3 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 PSC72657.1 - 0.015 15.0 0.0 0.015 15.0 0.0 1.8 2 0 0 2 2 2 0 Putative esterase zf-C3HC4_3 PF13920.6 PSC72658.1 - 4e-09 36.2 1.7 4e-09 36.2 1.7 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PSC72658.1 - 2e-05 24.4 2.5 4.4e-05 23.3 2.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-P11 PF03854.14 PSC72658.1 - 0.00013 21.5 3.4 0.00013 21.5 3.4 1.9 2 0 0 2 2 2 1 P-11 zinc finger zf-RING_2 PF13639.6 PSC72658.1 - 0.00069 19.9 2.3 0.00069 19.9 2.3 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 PSC72658.1 - 0.0025 17.7 1.3 0.0057 16.5 1.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 PSC72658.1 - 0.027 14.3 1.0 0.045 13.5 1.0 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 PSC72658.1 - 0.054 13.5 1.3 0.11 12.5 1.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain RecR PF02132.15 PSC72658.1 - 0.23 11.0 5.8 0.055 13.0 1.4 2.2 3 0 0 3 3 3 0 RecR protein Umbravirus_LDM PF04817.12 PSC72658.1 - 0.25 10.7 0.8 6.5 6.0 0.0 2.3 2 0 0 2 2 2 0 Umbravirus long distance movement (LDM) family IBN_N PF03810.19 PSC72659.1 - 0.00063 19.6 0.1 0.0035 17.2 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain IBN_N PF03810.19 PSC72660.1 - 0.00062 19.6 0.1 0.0035 17.2 0.0 2.5 2 0 0 2 2 2 1 Importin-beta N-terminal domain TPMT PF05724.11 PSC72662.1 - 3e-27 95.7 0.0 3.6e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Methyltransf_25 PF13649.6 PSC72662.1 - 1.3e-06 29.0 0.0 2e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC72662.1 - 8.5e-05 23.1 0.0 0.00013 22.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC72662.1 - 0.14 12.0 0.0 0.2 11.4 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain nlz1 PF12402.8 PSC72662.1 - 0.17 12.4 2.0 0.18 12.3 0.3 1.9 2 0 0 2 2 2 0 NocA-like zinc-finger protein 1 AA_permease_2 PF13520.6 PSC72663.1 - 4e-55 187.4 49.5 4.8e-55 187.1 49.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 PSC72663.1 - 7.1e-18 64.4 40.8 1.1e-17 63.9 40.8 1.1 1 0 0 1 1 1 1 Amino acid permease TMEM72 PF16054.5 PSC72663.1 - 0.68 9.6 7.4 0.92 9.2 0.3 2.4 2 0 0 2 2 2 0 Transmembrane protein family 72 Fun_ATP-synt_8 PF05933.13 PSC72663.1 - 3.5 7.9 7.6 0.49 10.6 0.2 3.1 3 0 0 3 3 3 0 Fungal ATP synthase protein 8 (A6L) NARG2_C PF10505.9 PSC72664.1 - 3.4e-10 39.8 0.0 0.00035 20.1 0.0 2.4 2 0 0 2 2 2 2 NMDA receptor-regulated gene protein 2 C-terminus Ndc1_Nup PF09531.10 PSC72664.1 - 2.4 6.8 23.4 0.33 9.6 5.0 2.2 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Glyco_transf_8 PF01501.20 PSC72665.1 - 3.3e-19 69.4 0.0 4.5e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 PSC72665.1 - 0.02 14.3 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Nucleotid_trans PF03407.16 PSC72665.1 - 0.029 14.3 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Glyco_transf_8 PF01501.20 PSC72666.1 - 3.3e-19 69.4 0.0 4.5e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 PSC72666.1 - 0.02 14.3 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Mannosyltransferase putative Nucleotid_trans PF03407.16 PSC72666.1 - 0.029 14.3 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Cyt-b5 PF00173.28 PSC72667.1 - 9.5e-23 80.1 0.0 1.3e-22 79.8 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain HMG_box_5 PF14887.6 PSC72668.1 - 0.015 15.3 0.4 0.015 15.3 0.4 2.1 2 0 0 2 2 2 0 HMG (high mobility group) box 5 DUF919 PF06034.11 PSC72668.1 - 0.14 12.0 0.2 0.32 10.9 0.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Phage_GP20 PF06810.11 PSC72668.1 - 0.16 11.8 3.6 0.37 10.6 0.6 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 HMG_box_5 PF14887.6 PSC72669.1 - 0.012 15.5 0.4 0.012 15.5 0.4 2.1 2 0 0 2 2 2 0 HMG (high mobility group) box 5 DUF919 PF06034.11 PSC72669.1 - 0.13 12.1 0.2 0.3 11.0 0.2 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) Phage_GP20 PF06810.11 PSC72669.1 - 0.14 11.9 3.4 0.37 10.6 0.6 2.4 2 0 0 2 2 2 0 Phage minor structural protein GP20 SelR PF01641.18 PSC72670.1 - 1.2e-49 167.4 0.1 1.4e-49 167.2 0.1 1.0 1 0 0 1 1 1 1 SelR domain Ribosomal_L37e PF01907.19 PSC72670.1 - 0.01 16.0 3.1 0.34 11.1 0.2 2.5 2 0 0 2 2 2 1 Ribosomal protein L37e zf-Mss51 PF13824.6 PSC72670.1 - 0.011 15.8 1.8 0.61 10.2 0.1 2.9 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_10 PF10058.9 PSC72670.1 - 0.048 13.4 0.1 0.81 9.5 0.0 2.2 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein DZR PF12773.7 PSC72670.1 - 0.1 12.6 2.3 0.86 9.7 2.4 2.2 1 1 0 1 1 1 0 Double zinc ribbon Yippee-Mis18 PF03226.14 PSC72670.1 - 0.11 12.8 0.8 0.55 10.5 0.8 2.0 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-ribbon_3 PF13248.6 PSC72670.1 - 10 5.7 9.5 2.7 7.5 0.2 3.2 4 0 0 4 4 4 0 zinc-ribbon domain 4HBT PF03061.22 PSC72671.1 - 8.1e-15 54.9 0.1 1.3e-14 54.2 0.1 1.4 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_2 PF13279.6 PSC72671.1 - 8.2e-11 42.5 0.0 9.2e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily NAD_binding_9 PF13454.6 PSC72671.1 - 0.11 12.5 1.0 0.12 12.4 0.2 1.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding PEX11 PF05648.14 PSC72672.1 - 1.7e-37 129.0 0.0 2e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) TcA_TcB_BD PF18276.1 PSC72672.1 - 0.085 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Tc toxin complex TcA C-terminal TcB-binding domain Epimerase PF01370.21 PSC72673.1 - 1.3e-08 34.6 0.0 6.9e-07 29.0 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 PSC72673.1 - 9.6e-07 28.6 0.0 1.2e-06 28.3 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 PSC72673.1 - 0.0003 20.7 0.0 0.00046 20.1 0.0 1.4 1 1 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 PSC72673.1 - 0.0013 17.9 0.0 0.014 14.5 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain PP-binding PF00550.25 PSC72674.1 - 4.4e-12 46.2 0.2 5.4e-11 42.7 0.1 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 PSC72674.1 - 0.0017 18.5 0.0 0.0033 17.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-carrier HEAT_PBS PF03130.16 PSC72674.1 - 0.75 10.6 5.8 2.6 9.0 0.0 4.3 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat DAO PF01266.24 PSC72675.1 - 9.5e-56 189.9 9.8 1.2e-55 189.6 9.8 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 PSC72675.1 - 1.6e-06 27.6 1.2 0.0014 18.0 0.4 2.3 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 PSC72675.1 - 4.4e-06 26.1 4.1 0.0014 17.8 0.4 2.6 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 PSC72675.1 - 0.00019 20.7 0.8 0.056 12.7 0.3 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PSC72675.1 - 0.00069 19.8 0.2 0.0016 18.6 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.27 PSC72675.1 - 0.048 14.2 0.2 0.12 13.0 0.2 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Aconitase PF00330.20 PSC72676.1 - 9.8e-153 509.4 0.0 1.2e-152 509.1 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 PSC72676.1 - 7.3e-46 155.7 0.0 1.6e-45 154.7 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain Aldo_ket_red PF00248.21 PSC72677.1 - 4.5e-22 78.6 0.0 1.3e-21 77.1 0.0 1.7 2 0 0 2 2 2 1 Aldo/keto reductase family Semialdhyde_dh PF01118.24 PSC72677.1 - 0.13 12.7 1.0 0.28 11.6 0.1 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Aa_trans PF01490.18 PSC72678.1 - 5.2e-58 196.7 9.2 4.4e-35 121.2 5.5 2.2 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Ank_4 PF13637.6 PSC72679.1 - 8.6e-20 70.8 4.8 6e-09 36.3 0.2 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_2 PF12796.7 PSC72679.1 - 2.3e-19 69.7 1.5 3.2e-11 43.6 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PSC72679.1 - 3.8e-15 54.5 2.1 0.038 14.5 0.0 5.5 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.6 PSC72679.1 - 2.3e-12 46.9 6.2 2e-10 40.7 0.2 3.5 2 2 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 PSC72679.1 - 2.9e-08 33.8 8.9 0.00017 21.9 0.1 4.1 5 0 0 5 5 5 2 Ankyrin repeat PCI PF01399.27 PSC72680.1 - 3.5e-21 75.7 0.7 2.5e-20 72.9 0.0 2.6 2 1 0 2 2 2 1 PCI domain GCP_N_terminal PF17681.1 PSC72680.1 - 0.00073 19.2 1.4 0.41 10.2 1.3 2.2 2 0 0 2 2 2 2 Gamma tubulin complex component N-terminal TPR_7 PF13176.6 PSC72680.1 - 0.0013 18.6 1.1 7.2 6.9 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_20 PF14561.6 PSC72680.1 - 0.0079 16.5 2.6 0.011 16.1 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 PSC72680.1 - 0.069 14.0 6.3 0.44 11.5 0.1 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.6 PSC72680.1 - 0.09 13.0 1.2 1.8 9.0 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 PSC72680.1 - 0.19 12.4 3.3 10 7.0 0.2 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat dsDNA_bind PF01984.20 PSC72680.1 - 0.4 11.0 0.0 0.4 11.0 0.0 2.3 3 0 0 3 3 3 0 Double-stranded DNA-binding domain LMBR1 PF04791.16 PSC72681.1 - 1.9e-63 215.2 24.6 5.6e-38 131.1 12.8 2.1 1 1 1 2 2 2 2 LMBR1-like membrane protein Kelch_6 PF13964.6 PSC72682.1 - 3.1e-14 52.7 0.3 0.00019 21.6 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 PSC72682.1 - 2.1e-10 40.4 1.1 1.6e-07 31.2 0.0 3.9 4 1 0 4 4 4 1 Galactose oxidase, central domain Kelch_2 PF07646.15 PSC72682.1 - 4.3e-09 36.0 1.3 0.22 11.6 0.0 4.1 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 PSC72682.1 - 1e-08 35.2 3.6 3.2e-06 27.3 0.0 5.1 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.6 PSC72682.1 - 1e-07 31.7 0.1 3.5e-06 26.9 0.0 2.9 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.25 PSC72682.1 - 3.1e-05 23.5 2.3 0.13 11.9 0.1 4.1 3 0 0 3 3 3 2 Kelch motif fn3 PF00041.21 PSC72682.1 - 0.00032 21.0 0.0 0.00064 20.0 0.0 1.4 1 0 0 1 1 1 1 Fibronectin type III domain Spc7 PF08317.11 PSC72682.1 - 5.7 5.7 9.2 5.7 5.7 8.2 1.4 1 1 0 1 1 1 0 Spc7 kinetochore protein ACBP PF00887.19 PSC72683.1 - 2.7e-22 78.8 0.1 4.7e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_4 PF13637.6 PSC72683.1 - 1.7e-14 54.0 3.9 2.4e-10 40.7 0.8 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC72683.1 - 1.7e-13 50.5 7.7 3.8e-08 33.5 1.9 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 PSC72683.1 - 4.2e-13 49.7 0.5 8.5e-13 48.7 0.5 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PSC72683.1 - 5.8e-12 44.7 0.2 0.00011 22.3 0.1 3.5 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 PSC72683.1 - 2.7e-10 40.2 4.7 2.6e-06 27.6 0.7 3.2 3 0 0 3 3 3 2 Ankyrin repeat Nucleoporin_FG PF13634.6 PSC72685.1 - 3.1e-05 24.7 67.0 0.00069 20.4 17.9 4.1 3 1 1 4 4 4 3 Nucleoporin FG repeat region CTD PF12815.7 PSC72685.1 - 8.8e-05 23.0 3.4 8.8e-05 23.0 3.4 3.7 4 2 0 4 4 4 1 Spt5 C-terminal nonapeptide repeat binding Spt4 Med11 PF10280.9 PSC72685.1 - 0.68 10.4 3.5 0.53 10.7 0.2 2.2 2 0 0 2 2 2 0 Mediator complex protein TraB PF01963.17 PSC72687.1 - 7.5e-07 29.3 0.1 0.0025 17.8 0.0 3.3 3 0 0 3 3 3 3 TraB family RTTN_N PF14726.6 PSC72688.1 - 2.1e-06 28.5 0.8 8.4e-05 23.3 0.0 3.7 4 0 0 4 4 4 1 Rotatin, an armadillo repeat protein, centriole functioning AAA PF00004.29 PSC72689.1 - 4.4e-11 43.3 0.0 9.4e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PSC72689.1 - 0.00016 21.4 0.0 0.00032 20.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DNA_pol3_delta PF06144.13 PSC72689.1 - 0.00046 20.0 0.0 0.0007 19.4 0.0 1.2 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_25 PF13481.6 PSC72689.1 - 0.00095 18.8 0.2 0.026 14.1 0.1 2.8 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.6 PSC72689.1 - 0.002 18.2 0.0 0.0033 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 PSC72689.1 - 0.0025 17.8 0.0 0.025 14.5 0.0 2.2 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_24 PF13479.6 PSC72689.1 - 0.016 15.0 0.0 0.025 14.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PSC72689.1 - 0.018 15.4 0.0 0.15 12.5 0.0 2.7 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 PSC72689.1 - 0.035 14.6 0.0 0.072 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 PSC72689.1 - 0.037 14.0 0.0 0.075 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PSC72689.1 - 0.051 13.9 0.9 1.1 9.5 0.1 2.7 2 1 0 3 3 2 0 AAA domain AAA_33 PF13671.6 PSC72689.1 - 0.096 12.8 0.0 0.29 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 PSC72689.1 - 0.1 11.9 0.0 0.26 10.6 0.0 1.6 2 0 0 2 2 2 0 KaiC T2SSE PF00437.20 PSC72689.1 - 0.15 11.1 0.0 0.27 10.3 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein FXMRP1_C_core PF12235.8 PSC72689.1 - 0.26 11.9 8.9 4.4 8.0 3.3 3.3 3 0 0 3 3 3 0 Fragile X-related 1 protein core C terminal NTPase_1 PF03266.15 PSC72689.1 - 0.26 11.2 0.1 0.69 9.8 0.0 1.6 1 1 1 2 2 2 0 NTPase zf-C3HC4_3 PF13920.6 PSC72690.1 - 5.4e-07 29.4 15.4 1.1e-06 28.4 15.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC72690.1 - 0.021 15.1 18.3 0.021 15.1 18.3 1.9 2 0 0 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.6 PSC72690.1 - 1.7 8.6 15.9 3.3 7.6 15.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 TFIIA PF03153.13 PSC72691.1 - 1.7 8.6 11.2 2.2 8.2 11.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 PSC72691.1 - 3.1 7.3 8.0 4.2 6.9 8.0 1.1 1 0 0 1 1 1 0 Spt20 family Pkinase PF00069.25 PSC72692.1 - 3.6e-56 190.4 0.0 4.4e-56 190.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC72692.1 - 4.5e-28 98.2 0.0 5.4e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC72692.1 - 8.1e-06 25.3 0.0 1.5e-05 24.4 0.0 1.4 1 1 0 1 1 1 1 Kinase-like APH PF01636.23 PSC72692.1 - 0.0029 17.6 0.2 2.4 8.0 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family TFIIS_C PF01096.18 PSC72694.1 - 1.1e-14 54.0 1.9 1.6e-14 53.5 1.9 1.2 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 PSC72694.1 - 0.0019 18.0 5.7 0.0069 16.2 0.3 3.0 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zf-TFIIB PF13453.6 PSC72694.1 - 0.11 11.8 1.4 0.25 10.7 1.4 1.7 1 0 0 1 1 1 0 Transcription factor zinc-finger Baculo_LEF5_C PF11792.8 PSC72694.1 - 0.18 11.5 0.2 0.18 11.5 0.2 1.6 2 0 0 2 2 2 0 Baculoviridae late expression factor 5 C-terminal domain Zn-ribbon_8 PF09723.10 PSC72694.1 - 0.88 9.7 6.4 1.5 9.0 0.1 2.5 2 0 0 2 2 2 0 Zinc ribbon domain zf-H2C2_2 PF13465.6 PSC72694.1 - 1.2 9.7 4.7 0.69 10.5 0.5 2.2 2 0 0 2 2 2 0 Zinc-finger double domain Ank_2 PF12796.7 PSC72695.1 - 5.8e-20 71.7 0.5 5.8e-11 42.8 0.2 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC72695.1 - 2.6e-17 62.6 2.7 5.6e-08 32.9 0.4 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC72695.1 - 4.6e-14 52.6 4.1 3.3e-06 27.5 0.4 3.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.30 PSC72695.1 - 2e-13 50.1 8.2 2e-05 24.8 0.0 3.4 2 1 1 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 PSC72695.1 - 1.5e-11 43.5 3.1 0.00042 20.6 0.0 4.6 5 0 0 5 5 5 2 Ankyrin repeat RRP36 PF06102.12 PSC72696.1 - 5.5e-43 146.8 20.7 7.3e-43 146.4 20.7 1.2 1 0 0 1 1 1 1 rRNA biogenesis protein RRP36 AAA PF00004.29 PSC72697.1 - 2.6e-17 63.5 0.0 4.3e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 PSC72697.1 - 9.4e-17 61.3 0.0 1.4e-10 41.2 0.0 2.2 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rep_fac_C PF08542.11 PSC72697.1 - 2e-14 53.8 0.0 7.5e-14 51.9 0.0 2.0 2 0 0 2 2 2 1 Replication factor C C-terminal domain AAA_22 PF13401.6 PSC72697.1 - 9.6e-07 29.2 0.0 0.003 17.9 0.0 2.4 1 1 1 2 2 2 2 AAA domain Rad17 PF03215.15 PSC72697.1 - 3.6e-06 27.0 0.0 7.3e-06 26.0 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 PSC72697.1 - 1.3e-05 25.0 0.0 3.4e-05 23.7 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PSC72697.1 - 1.5e-05 25.4 0.1 0.00063 20.2 0.0 2.6 2 1 1 3 3 3 1 AAA ATPase domain Mg_chelatase PF01078.21 PSC72697.1 - 0.00015 21.3 0.0 0.0063 15.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_assoc_2 PF16193.5 PSC72697.1 - 0.0003 21.1 0.0 0.0008 19.7 0.0 1.8 1 0 0 1 1 1 1 AAA C-terminal domain AAA_11 PF13086.6 PSC72697.1 - 0.00095 19.0 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 PSC72697.1 - 0.0015 18.6 0.0 0.0026 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 PSC72697.1 - 0.0015 18.5 0.0 0.0051 16.8 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.6 PSC72697.1 - 0.002 17.9 0.0 0.0043 16.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PSC72697.1 - 0.0025 17.5 0.0 0.0063 16.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain DNA_pol3_delta PF06144.13 PSC72697.1 - 0.006 16.4 0.0 0.018 14.8 0.0 1.7 2 0 0 2 2 2 1 DNA polymerase III, delta subunit AAA_25 PF13481.6 PSC72697.1 - 0.019 14.6 0.1 0.18 11.3 0.0 2.2 1 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 PSC72697.1 - 0.021 14.8 0.0 0.16 11.9 0.0 2.3 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 PSC72697.1 - 0.022 15.1 0.1 0.31 11.4 0.0 2.4 2 1 0 3 3 3 0 AAA domain PhoH PF02562.16 PSC72697.1 - 0.051 13.0 0.0 0.79 9.1 0.0 2.1 2 0 0 2 2 2 0 PhoH-like protein ADK PF00406.22 PSC72697.1 - 0.053 13.6 0.2 4 7.5 0.0 2.9 2 1 1 3 3 3 0 Adenylate kinase AAA_7 PF12775.7 PSC72697.1 - 0.061 12.8 0.0 0.097 12.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_33 PF13671.6 PSC72697.1 - 0.091 12.9 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 PSC72697.1 - 0.098 11.7 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Sigma54_activat PF00158.26 PSC72697.1 - 0.1 12.3 0.0 0.69 9.6 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain TIP49 PF06068.13 PSC72697.1 - 0.1 11.8 0.0 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain DEAD PF00270.29 PSC72697.1 - 0.13 12.0 0.0 7.7 6.2 0.0 2.2 2 0 0 2 2 2 0 DEAD/DEAH box helicase DUF2075 PF09848.9 PSC72697.1 - 0.14 11.4 0.0 0.93 8.7 0.0 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF815 PF05673.13 PSC72697.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RNA_helicase PF00910.22 PSC72697.1 - 0.2 12.0 0.0 0.44 11.0 0.0 1.6 1 0 0 1 1 1 0 RNA helicase MOZ_SAS PF01853.18 PSC72698.1 - 5.4e-83 277.0 0.0 8.9e-83 276.3 0.0 1.4 1 0 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 PSC72698.1 - 6.8e-22 76.8 1.8 6.8e-22 76.8 1.8 2.0 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 PSC72698.1 - 2.7e-17 62.4 0.4 6.1e-17 61.2 0.4 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 PSC72698.1 - 0.001 19.5 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PSC72698.1 - 0.083 13.1 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family ANAPC8 PF04049.13 PSC72698.1 - 0.14 12.2 0.1 0.6 10.2 0.0 2.0 2 0 0 2 2 2 0 Anaphase promoting complex subunit 8 / Cdc23 GRIP PF01465.20 PSC72699.1 - 1.1e-09 38.0 0.0 2.6e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 GRIP domain CCDC144C PF14915.6 PSC72699.1 - 0.0007 18.8 25.8 0.0007 18.8 25.8 9.3 3 2 3 8 8 8 1 CCDC144C protein coiled-coil region GAS PF13851.6 PSC72699.1 - 0.0058 16.0 15.2 0.0058 16.0 15.2 13.4 4 3 7 13 13 13 3 Growth-arrest specific micro-tubule binding CENP-F_leu_zip PF10473.9 PSC72699.1 - 0.0074 16.3 15.4 0.0074 16.3 15.4 14.7 6 3 10 16 16 16 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WD40_alt PF14077.6 PSC72699.1 - 0.076 12.9 1.6 5.3 7.0 0.0 4.7 4 0 0 4 4 4 0 Alternative WD40 repeat motif Shugoshin_N PF07558.11 PSC72699.1 - 0.75 9.7 4.8 19 5.2 0.0 4.3 4 0 0 4 4 4 0 Shugoshin N-terminal coiled-coil region MFS_1 PF07690.16 PSC72700.1 - 5.5e-47 160.4 37.6 5.5e-47 160.4 37.6 1.5 1 1 1 2 2 2 1 Major Facilitator Superfamily BT1 PF03092.16 PSC72700.1 - 0.18 10.0 16.6 0.15 10.3 4.5 2.6 2 1 1 3 3 3 0 BT1 family tRNA_U5-meth_tr PF05958.11 PSC72701.1 - 3.6e-141 470.3 0.0 4.2e-141 470.1 0.0 1.0 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_25 PF13649.6 PSC72701.1 - 1.3e-06 29.0 0.1 2.6e-05 24.8 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_15 PF09445.10 PSC72701.1 - 0.00053 19.6 0.0 0.00088 18.9 0.0 1.4 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase DREV PF05219.12 PSC72701.1 - 0.00067 18.8 0.0 0.0012 18.0 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_31 PF13847.6 PSC72701.1 - 0.00071 19.4 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC72701.1 - 0.00091 19.9 0.0 0.0036 18.0 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC72701.1 - 0.0011 19.6 0.1 0.005 17.5 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PSC72701.1 - 0.0033 17.0 0.0 0.0068 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ribosomal_60s PF00428.19 PSC72701.1 - 0.013 16.1 5.9 0.013 16.1 5.9 3.0 3 0 0 3 3 2 0 60s Acidic ribosomal protein RrnaAD PF00398.20 PSC72701.1 - 0.041 13.0 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltrans_SAM PF10672.9 PSC72701.1 - 0.055 12.6 0.0 0.081 12.1 0.0 1.2 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase Methyltransf_4 PF02390.17 PSC72701.1 - 0.073 12.5 0.0 0.14 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PrmA PF06325.13 PSC72701.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 PSC72701.1 - 0.12 11.9 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 Nodulation protein S (NodS) VPS9 PF02204.18 PSC72702.1 - 1.4e-18 67.0 0.0 2.4e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 PSC72702.1 - 6.2e-12 45.7 0.0 1.1e-11 44.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5601) HsbA PF12296.8 PSC72703.1 - 0.004 17.6 4.0 0.0061 17.0 1.1 2.6 3 0 0 3 3 3 1 Hydrophobic surface binding protein A Spc7 PF08317.11 PSC72703.1 - 0.15 10.9 20.9 0.055 12.3 17.8 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 PSC72703.1 - 0.18 11.8 18.4 0.63 10.1 14.8 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 V_ATPase_I PF01496.19 PSC72703.1 - 0.7 7.7 2.3 0.84 7.5 2.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family THOC7 PF05615.13 PSC72703.1 - 1.1 9.6 19.5 2.8 8.2 19.5 1.7 1 1 0 1 1 1 0 Tho complex subunit 7 ATG16 PF08614.11 PSC72703.1 - 1.7 8.8 31.0 0.29 11.3 25.4 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HAUS-augmin3 PF14932.6 PSC72703.1 - 1.8 8.1 17.2 3.9 7.0 16.8 1.6 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 3 Fez1 PF06818.15 PSC72703.1 - 2.8 8.3 20.3 2.9 8.3 17.1 1.9 1 1 1 2 2 2 0 Fez1 Macoilin PF09726.9 PSC72703.1 - 3.8 5.9 12.8 4.6 5.7 12.8 1.1 1 0 0 1 1 1 0 Macoilin family JUPITER PF17054.5 PSC72704.1 - 8.6e-05 22.2 0.4 0.23 10.9 0.0 2.2 2 0 0 2 2 2 2 Microtubule-Associated protein Jupiter SAP PF02037.27 PSC72704.1 - 0.00068 19.3 0.0 0.001 18.8 0.0 1.2 1 0 0 1 1 1 1 SAP domain NDK PF00334.19 PSC72705.1 - 3.5e-52 176.0 0.0 5.8e-52 175.3 0.0 1.4 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF4201 PF13870.6 PSC72705.1 - 0.021 14.5 0.8 0.036 13.8 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Spc7 PF08317.11 PSC72705.1 - 0.21 10.4 2.8 0.3 9.9 2.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Spt20 PF12090.8 PSC72706.1 - 0.34 10.5 6.4 0.51 9.9 6.4 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 PSC72706.1 - 1.6 8.6 9.3 2.5 8.0 9.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rrn6 PF10214.9 PSC72706.1 - 6 5.2 8.4 8.2 4.8 8.4 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF3535 PF12054.8 PSC72707.1 - 2.1e-61 208.5 2.4 2.1e-61 208.5 2.4 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 PSC72707.1 - 5.3e-57 193.1 0.0 8.8e-57 192.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC72707.1 - 2.8e-12 46.9 0.0 6e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HEAT PF02985.22 PSC72707.1 - 9.9e-05 22.3 40.3 6.2 7.4 0.2 10.6 10 0 0 10 10 10 6 HEAT repeat IFRD PF05004.13 PSC72707.1 - 6.5 5.8 9.9 8.5 5.4 0.1 4.2 4 0 0 4 4 4 0 Interferon-related developmental regulator (IFRD) AAA PF00004.29 PSC72708.1 - 3.7e-73 244.2 0.0 6.1e-40 136.7 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PSC72708.1 - 8.3e-13 47.9 9.7 2.9e-09 36.6 0.3 3.3 3 0 0 3 3 2 2 AAA+ lid domain AAA_22 PF13401.6 PSC72708.1 - 9.8e-10 38.8 1.0 0.011 16.0 0.0 4.2 3 1 1 4 4 4 2 AAA domain AAA_5 PF07728.14 PSC72708.1 - 3e-09 37.0 0.0 0.0052 16.8 0.1 3.3 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 PSC72708.1 - 1.6e-08 34.5 0.0 0.0084 15.9 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain NACHT PF05729.12 PSC72708.1 - 2e-08 34.3 0.3 0.039 13.9 0.0 4.3 3 1 1 4 4 4 2 NACHT domain AAA_33 PF13671.6 PSC72708.1 - 3.5e-08 33.7 1.8 8.6e-05 22.7 0.1 3.1 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 PSC72708.1 - 3.6e-08 34.0 22.9 3.1e-06 27.7 1.6 5.3 4 2 1 5 5 5 2 AAA ATPase domain IstB_IS21 PF01695.17 PSC72708.1 - 3.4e-07 30.2 0.2 0.0015 18.3 0.1 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 PSC72708.1 - 1e-06 29.3 0.0 0.01 16.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.6 PSC72708.1 - 1.1e-06 29.0 0.6 0.0045 17.2 0.2 3.8 2 1 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 PSC72708.1 - 3.2e-06 26.7 4.4 0.024 14.0 0.3 3.2 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 PSC72708.1 - 3.4e-05 24.2 0.0 0.44 11.0 0.0 2.4 2 0 0 2 2 2 2 RNA helicase Viral_helicase1 PF01443.18 PSC72708.1 - 3.7e-05 23.6 0.0 0.06 13.1 0.0 2.3 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.6 PSC72708.1 - 7.7e-05 22.3 5.4 0.24 10.9 0.0 3.9 3 1 0 3 3 3 2 AAA domain TsaE PF02367.17 PSC72708.1 - 0.00011 22.2 0.0 0.16 12.0 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_24 PF13479.6 PSC72708.1 - 0.00012 21.9 0.0 0.41 10.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.6 PSC72708.1 - 0.0003 21.2 0.0 0.2 12.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 PSC72708.1 - 0.0003 20.6 0.0 0.041 13.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 PSC72708.1 - 0.00058 19.2 0.0 0.093 11.9 0.0 2.2 2 0 0 2 2 2 1 TIP49 P-loop domain ATPase PF06745.13 PSC72708.1 - 0.00065 19.1 0.0 0.81 9.0 0.0 2.3 2 0 0 2 2 2 2 KaiC AAA_2 PF07724.14 PSC72708.1 - 0.00096 19.3 0.0 0.81 9.8 0.0 3.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) Zeta_toxin PF06414.12 PSC72708.1 - 0.0019 17.5 0.1 0.22 10.8 0.0 2.6 2 0 0 2 2 2 1 Zeta toxin ABC_tran PF00005.27 PSC72708.1 - 0.0037 17.8 0.2 1.9 9.0 0.0 2.9 2 1 0 2 2 2 1 ABC transporter PhoH PF02562.16 PSC72708.1 - 0.0047 16.4 1.5 0.91 8.9 0.0 2.3 2 0 0 2 2 2 1 PhoH-like protein AAA_14 PF13173.6 PSC72708.1 - 0.0057 16.7 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.11 PSC72708.1 - 0.0078 16.1 0.0 4.9 7.0 0.0 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 PSC72708.1 - 0.024 13.8 0.0 5.9 6.0 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 PSC72708.1 - 0.027 14.4 0.0 2.5 8.0 0.0 2.4 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 PSC72708.1 - 0.027 13.6 0.1 5 6.1 0.1 2.2 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Sigma54_activat PF00158.26 PSC72708.1 - 0.03 14.0 0.0 6 6.5 0.0 3.0 3 0 0 3 3 3 0 Sigma-54 interaction domain AAA_19 PF13245.6 PSC72708.1 - 0.032 14.6 0.2 6.6 7.1 0.1 2.7 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 PSC72708.1 - 0.035 13.3 0.0 4.1 6.5 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 PSC72708.1 - 0.043 13.3 0.0 6.1 6.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region Sigma54_activ_2 PF14532.6 PSC72708.1 - 0.052 13.7 0.0 4.2 7.5 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain NTPase_1 PF03266.15 PSC72708.1 - 0.074 13.0 0.0 22 4.9 0.0 3.1 3 0 0 3 3 3 0 NTPase Bac_DnaA PF00308.18 PSC72708.1 - 0.1 12.4 0.0 3.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein Rad17 PF03215.15 PSC72708.1 - 0.11 12.4 0.0 4.1 7.3 0.0 2.2 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_29 PF13555.6 PSC72708.1 - 0.13 12.0 0.0 8.5 6.2 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain cobW PF02492.19 PSC72708.1 - 0.17 11.4 0.1 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain HTH_55 PF18622.1 PSC72708.1 - 1.3 9.4 2.6 9.6 6.6 0.1 2.7 2 0 0 2 2 2 0 RctB helix turn helix domain Form_Nir_trans PF01226.17 PSC72709.1 - 1e-64 218.1 23.5 1.5e-64 217.6 23.5 1.2 1 0 0 1 1 1 1 Formate/nitrite transporter UAA PF08449.11 PSC72710.1 - 1.7e-59 201.5 4.3 2.2e-59 201.1 4.3 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 PSC72710.1 - 0.00012 22.2 10.2 0.026 14.7 4.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family Nup54 PF13874.6 PSC72710.1 - 0.45 10.6 4.3 2.9 8.0 3.4 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Ribosomal_L30_N PF08079.12 PSC72710.1 - 2.8 8.3 8.4 0.74 10.1 1.8 2.4 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain UAA PF08449.11 PSC72711.1 - 1.6e-59 201.6 4.3 2.1e-59 201.2 4.3 1.1 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 PSC72711.1 - 0.00012 22.3 10.2 0.025 14.8 4.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family PAN_1 PF00024.26 PSC72711.1 - 0.15 12.1 0.7 5.2 7.1 0.1 2.4 2 0 0 2 2 2 0 PAN domain Nup54 PF13874.6 PSC72711.1 - 0.43 10.7 4.3 2.9 8.0 3.4 2.2 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 Ribosomal_L30_N PF08079.12 PSC72711.1 - 2.6 8.3 8.4 0.72 10.1 1.8 2.4 2 0 0 2 2 2 0 Ribosomal L30 N-terminal domain P5CR_dimer PF14748.6 PSC72712.1 - 1.5e-37 127.9 1.3 1.5e-37 127.9 1.3 2.8 3 0 0 3 3 3 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 PSC72712.1 - 1.3e-18 67.4 1.0 2.8e-18 66.3 0.2 2.1 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent AP2 PF00847.20 PSC72712.1 - 2.4e-16 59.7 13.7 1.3e-08 34.9 2.1 2.8 3 0 0 3 3 3 2 AP2 domain NAD_binding_2 PF03446.15 PSC72712.1 - 4.5e-06 26.9 0.1 1.1e-05 25.6 0.1 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PDH PF02153.17 PSC72712.1 - 0.00087 18.4 1.0 0.0013 17.8 0.2 1.6 2 0 0 2 2 2 1 Prephenate dehydrogenase ApbA PF02558.16 PSC72712.1 - 0.0011 18.6 0.2 0.0047 16.6 0.0 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 PSC72712.1 - 0.0019 18.2 0.9 0.0063 16.5 0.9 1.9 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 PSC72712.1 - 0.0037 17.3 0.0 0.007 16.4 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase OCD_Mu_crystall PF02423.15 PSC72712.1 - 0.059 12.3 0.3 0.11 11.5 0.3 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family 2-Hacid_dh_C PF02826.19 PSC72712.1 - 0.14 11.5 0.1 0.27 10.6 0.1 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rit1_C PF17184.4 PSC72713.1 - 5.8e-74 249.0 0.0 6.7e-60 202.8 0.0 2.3 2 1 0 2 2 2 2 Rit1 N-terminal domain UPF0029 PF01205.19 PSC72714.1 - 5.6e-34 116.6 0.0 8.2e-34 116.1 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized protein family UPF0029 RWD PF05773.22 PSC72714.1 - 2.2e-10 40.8 0.0 4.4e-10 39.9 0.0 1.5 1 1 0 1 1 1 1 RWD domain Nrap PF03813.14 PSC72715.1 - 1.2e-33 116.3 0.0 5.9e-28 97.8 0.0 2.2 2 0 0 2 2 2 2 Nrap protein domain 1 Nrap_D3 PF17404.2 PSC72715.1 - 1.9e-33 115.8 0.0 5.4e-33 114.3 0.0 1.7 2 0 0 2 2 2 1 Nrap protein domain 3 Nrap_D4 PF17405.2 PSC72715.1 - 2.9e-29 102.0 1.1 6.3e-29 100.9 0.0 2.0 2 0 0 2 2 2 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D2 PF17403.2 PSC72715.1 - 7.5e-26 90.7 0.0 2.8e-24 85.6 0.1 2.3 2 0 0 2 2 2 1 Nrap protein PAP/OAS-like domain Nrap_D5 PF17406.2 PSC72715.1 - 8.8e-25 87.3 0.0 9.6e-21 74.2 0.0 2.7 1 1 1 2 2 2 2 Nrap protein PAP/OAS1-like domain 5 Nrap_D6 PF17407.2 PSC72715.1 - 5.5e-12 46.1 0.0 1.1e-11 45.1 0.0 1.5 1 0 0 1 1 1 1 Nrap protein domain 6 Mito_fiss_reg PF05308.11 PSC72715.1 - 0.19 11.8 2.1 15 5.6 4.0 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator Chloroa_b-bind PF00504.21 PSC72716.1 - 1.8e-39 135.9 0.0 2.8e-39 135.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein RRM_1 PF00076.22 PSC72717.1 - 3.7e-37 126.0 0.0 7.3e-18 64.2 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 PSC72717.1 - 0.00024 20.7 0.1 0.42 10.3 0.0 2.3 2 0 0 2 2 2 2 Ribonuclease B OB domain RRM_7 PF16367.5 PSC72717.1 - 0.00034 20.7 0.0 0.0011 19.1 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif RRM_5 PF13893.6 PSC72717.1 - 0.026 14.1 0.0 0.076 12.6 0.0 1.7 1 1 1 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.8 PSC72717.1 - 0.13 12.3 0.1 1 9.5 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 WD40 PF00400.32 PSC72719.1 - 6.5e-14 52.1 3.0 6.5e-05 23.6 0.0 6.0 5 1 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC72719.1 - 4.1e-07 30.2 0.1 0.14 12.5 0.0 4.4 5 1 0 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 PSC72719.1 - 0.0039 16.8 0.3 0.0086 15.7 0.3 1.6 1 0 0 1 1 1 1 LisH-like dimerisation domain PQQ_3 PF13570.6 PSC72719.1 - 0.0057 17.1 3.4 16 6.1 0.2 4.9 4 0 0 4 4 4 1 PQQ-like domain Methyltransf_11 PF08241.12 PSC72721.1 - 1.8e-18 67.0 0.0 3.6e-18 66.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC72721.1 - 5.1e-18 65.6 0.0 1.2e-17 64.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC72721.1 - 3.5e-14 52.7 0.0 9.8e-14 51.2 0.0 1.6 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 PSC72721.1 - 6e-13 48.9 0.0 9.3e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC72721.1 - 4.4e-10 40.2 0.0 1.1e-09 38.9 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC72721.1 - 8.9e-05 22.4 0.0 0.0002 21.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.18 PSC72721.1 - 0.0001 21.7 0.0 0.00046 19.6 0.0 1.8 1 1 0 1 1 1 1 O-methyltransferase domain GidB PF02527.15 PSC72721.1 - 0.0068 15.8 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.14 PSC72721.1 - 0.017 14.6 0.0 0.029 13.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF2054 PF10218.9 PSC72722.1 - 3.4e-28 98.4 18.8 3.4e-28 98.4 18.8 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2054) zf-MYND PF01753.18 PSC72722.1 - 6.9e-06 26.0 4.4 6.9e-06 26.0 4.4 4.0 3 1 0 3 3 3 1 MYND finger Glyco_transf_18 PF15024.6 PSC72722.1 - 1.3e-05 24.0 2.1 2.1e-05 23.4 2.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 18 S6PP PF05116.13 PSC72722.1 - 0.00013 21.6 1.0 0.0034 16.9 0.0 3.0 3 1 0 3 3 3 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 PSC72722.1 - 0.0068 16.2 0.0 0.77 9.4 0.0 2.8 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase HEAT PF02985.22 PSC72723.1 - 0.0059 16.8 0.0 0.0059 16.8 0.0 5.2 5 0 0 5 5 5 1 HEAT repeat HEAT_EZ PF13513.6 PSC72723.1 - 0.081 13.5 0.1 0.081 13.5 0.1 6.2 6 1 1 7 7 7 0 HEAT-like repeat HEAT_2 PF13646.6 PSC72723.1 - 0.087 13.2 27.6 0.12 12.8 8.1 5.4 5 2 0 5 5 5 0 HEAT repeats SOG2 PF10428.9 PSC72723.1 - 0.74 9.0 6.8 1.2 8.3 6.8 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein Glyco_transf_90 PF05686.12 PSC72724.1 - 1.3e-37 129.7 0.0 2.9e-37 128.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 90 2OG-FeII_Oxy_3 PF13640.6 PSC72724.1 - 1.3e-08 35.6 0.0 5.6e-08 33.6 0.0 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 PSC72724.1 - 0.0049 16.0 0.0 0.0088 15.2 0.0 1.3 1 0 0 1 1 1 1 Poxvirus C4/C10 protein CarbopepD_reg_2 PF13715.6 PSC72724.1 - 0.18 11.8 0.0 0.39 10.8 0.0 1.5 1 0 0 1 1 1 0 CarboxypepD_reg-like domain LMWPc PF01451.21 PSC72725.1 - 1.4e-29 103.3 0.0 1.3e-27 96.9 0.0 2.8 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF563 PF04577.14 PSC72728.1 - 1.1e-09 38.7 0.0 2.6e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF563) RRM_1 PF00076.22 PSC72729.1 - 1.8e-10 40.5 0.0 8.7e-09 35.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Elf4 PF07011.11 PSC72730.1 - 1.5e-19 69.7 0.1 1.5e-19 69.7 0.1 1.6 2 0 0 2 2 2 1 Early Flowering 4 domain TRAM_LAG1_CLN8 PF03798.16 PSC72730.1 - 2.6e-12 46.9 6.5 3.6e-12 46.4 6.5 1.2 1 0 0 1 1 1 1 TLC domain Patched PF02460.18 PSC72731.1 - 6.7e-74 249.4 0.1 3.6e-43 147.8 0.0 2.1 2 0 0 2 2 2 2 Patched family NPC1_N PF16414.5 PSC72731.1 - 8.5e-66 222.0 1.5 1.4e-65 221.3 1.5 1.3 1 0 0 1 1 1 1 Niemann-Pick C1 N terminus Sterol-sensing PF12349.8 PSC72731.1 - 2.4e-53 180.1 10.4 2.1e-50 170.5 0.5 2.5 2 0 0 2 2 2 2 Sterol-sensing domain of SREBP cleavage-activation Folate_rec PF03024.14 PSC72731.1 - 1.7e-05 24.8 0.7 4e-05 23.6 0.7 1.6 1 0 0 1 1 1 1 Folate receptor family MMPL PF03176.15 PSC72731.1 - 0.00017 20.7 39.4 0.00063 18.8 10.3 2.9 3 1 0 3 3 3 2 MMPL family ORC5_C PF14630.6 PSC72732.1 - 8.3e-51 173.2 0.0 1e-50 172.9 0.0 1.1 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 5 C-terminus AAA_16 PF13191.6 PSC72732.1 - 1.3e-12 48.4 1.6 2.4e-12 47.6 0.2 2.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 PSC72732.1 - 2.4e-07 31.1 0.0 5.8e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_6 PF12774.7 PSC72732.1 - 0.0012 17.9 0.0 0.0022 17.0 0.0 1.3 1 0 0 1 1 1 1 Hydrolytic ATP binding site of dynein motor region AAA PF00004.29 PSC72732.1 - 0.0012 19.3 0.0 0.0053 17.2 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 PSC72732.1 - 0.0081 16.3 0.0 0.024 14.8 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PSC72732.1 - 0.028 14.2 0.0 0.081 12.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 PSC72732.1 - 0.05 13.6 0.0 0.099 12.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE TniB PF05621.11 PSC72732.1 - 0.069 12.6 0.0 0.18 11.2 0.0 1.7 1 0 0 1 1 1 0 Bacterial TniB protein ATPase_2 PF01637.18 PSC72732.1 - 0.083 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Sigma54_activat PF00158.26 PSC72732.1 - 0.096 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 PSC72732.1 - 0.12 12.3 0.0 0.37 10.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PSII_Pbs27 PF13326.6 PSC72733.1 - 1.1e-26 93.8 0.8 1.4e-26 93.5 0.8 1.2 1 0 0 1 1 1 1 Photosystem II Pbs27 SseC PF04888.12 PSC72733.1 - 0.011 15.4 0.6 0.016 14.9 0.6 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family FAD-SLDH PF12318.8 PSC72733.1 - 0.87 9.6 4.8 2.9 7.9 2.1 2.5 1 1 1 2 2 2 0 Membrane bound FAD containing D-sorbitol dehydrogenase GGACT PF06094.12 PSC72734.1 - 8.9e-21 74.7 0.0 1.2e-20 74.3 0.0 1.2 1 0 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like Helicase_C PF00271.31 PSC72735.1 - 0.0024 18.2 0.1 0.0057 17.0 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-ribbon_3 PF13248.6 PSC72736.1 - 0.34 10.4 2.0 2.6 7.6 0.2 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 PSC72736.1 - 1.6 8.5 4.7 5.5 6.8 0.1 2.8 3 0 0 3 3 3 0 Rubredoxin metal binding domain ABC2_membrane PF01061.24 PSC72737.1 - 1e-34 119.8 22.3 1e-34 119.8 22.3 2.0 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 PSC72737.1 - 2.4e-24 86.4 0.0 4.1e-24 85.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PSC72737.1 - 2.5e-07 30.1 20.7 4.3e-07 29.4 20.7 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_25 PF13481.6 PSC72737.1 - 0.0015 18.1 0.2 0.019 14.5 0.1 2.3 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PSC72737.1 - 0.018 15.4 1.9 0.021 15.2 0.1 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_21 PF13304.6 PSC72737.1 - 0.21 11.4 0.0 3.1 7.5 0.0 2.0 1 1 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Rad17 PF03215.15 PSC72737.1 - 0.24 11.3 0.1 0.46 10.4 0.1 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain zf-RING_4 PF14570.6 PSC72738.1 - 7.3e-19 67.3 13.6 1.3e-18 66.5 13.6 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_1 PF00076.22 PSC72738.1 - 7.8e-06 25.6 0.0 3.1e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.6 PSC72738.1 - 0.00081 19.2 10.7 0.0015 18.4 10.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC72738.1 - 0.027 14.8 12.4 0.052 13.9 12.4 1.5 1 0 0 1 1 1 0 Ring finger domain Baculo_IE-1 PF05290.11 PSC72738.1 - 0.41 10.6 5.2 0.82 9.6 5.2 1.5 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4 PF00097.25 PSC72738.1 - 2.3 8.1 12.7 4.4 7.3 12.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-UDP PF14569.6 PSC72738.1 - 2.6 8.2 4.8 4.5 7.5 4.8 1.3 1 0 0 1 1 1 0 Zinc-binding RING-finger Mito_carr PF00153.27 PSC72740.1 - 1.6e-58 194.6 2.7 1.2e-18 66.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein FTR PF01913.18 PSC72740.1 - 0.51 10.3 0.1 0.51 10.3 0.1 2.1 2 0 0 2 2 2 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase MCM PF00493.23 PSC72741.1 - 6.9e-98 326.2 0.0 1.1e-97 325.5 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PSC72741.1 - 5.5e-33 113.5 1.0 1.1e-32 112.5 1.0 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PSC72741.1 - 6.4e-26 90.6 0.4 1.6e-25 89.4 0.4 1.7 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 PSC72741.1 - 2.2e-09 37.9 0.0 6e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 PSC72741.1 - 2.1e-05 24.0 0.0 7.4e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 PSC72741.1 - 0.00055 19.8 0.0 0.0014 18.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PSC72741.1 - 0.00073 19.6 0.0 0.002 18.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 PSC72741.1 - 0.075 12.7 0.0 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Methyltransf_11 PF08241.12 PSC72742.1 - 4.8e-18 65.6 0.2 1.2e-17 64.3 0.1 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC72742.1 - 4.1e-15 56.0 0.0 6.3e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC72742.1 - 8e-15 55.3 0.3 1.7e-14 54.3 0.3 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC72742.1 - 8.3e-13 48.4 0.0 1.1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC72742.1 - 1.6e-12 48.0 0.1 2.7e-12 47.3 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 PSC72742.1 - 1.5e-08 34.3 0.0 2e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 PSC72742.1 - 0.00025 20.5 0.3 0.00035 20.1 0.3 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 PSC72742.1 - 0.00032 20.4 0.0 0.00046 19.9 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 PSC72742.1 - 0.00077 19.5 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PSC72742.1 - 0.00079 19.0 0.1 0.0014 18.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 PSC72742.1 - 0.0019 17.5 0.0 0.0027 17.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TPMT PF05724.11 PSC72742.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_9 PF08003.11 PSC72742.1 - 0.011 14.7 0.0 0.014 14.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) MetW PF07021.12 PSC72742.1 - 0.028 14.0 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW PCMT PF01135.19 PSC72742.1 - 0.078 12.7 0.2 0.12 12.1 0.2 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 PSC72742.1 - 0.078 12.4 0.0 0.1 12.0 0.0 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 PSC72742.1 - 0.21 11.5 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF3292 PF11696.8 PSC72743.1 - 0.02 13.3 4.1 0.043 12.2 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) CUE PF02845.16 PSC72743.1 - 0.02 14.6 0.0 40 4.0 0.0 4.6 4 0 0 4 4 4 0 CUE domain FAD_binding_1 PF00667.20 PSC72744.1 - 4.9e-39 134.2 0.0 6.7e-39 133.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 PSC72744.1 - 1.4e-28 99.9 0.0 5.4e-28 98.0 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 PSC72744.1 - 4e-12 46.7 0.0 6.9e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Pkinase_Tyr PF07714.17 PSC72745.1 - 1.8e-49 168.4 0.0 2.2e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC72745.1 - 3.7e-39 134.7 0.0 4.9e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 PSC72745.1 - 0.0022 16.9 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 PSC72746.1 - 1.8e-49 168.4 0.0 2.2e-49 168.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC72746.1 - 3.7e-39 134.7 0.0 4.9e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 PSC72746.1 - 0.0022 16.9 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Sod_Fe_C PF02777.18 PSC72747.1 - 3.4e-35 120.3 0.0 5.7e-35 119.6 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Ribosomal_S17 PF00366.20 PSC72747.1 - 6.1e-28 96.7 2.9 1e-27 96.0 2.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 Sod_Fe_N PF00081.22 PSC72747.1 - 6.7e-22 77.8 0.0 1.4e-21 76.8 0.0 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain AA_kinase PF00696.28 PSC72748.1 - 1e-22 81.0 0.0 1.4e-22 80.4 0.0 1.1 1 0 0 1 1 1 1 Amino acid kinase family BES1_N PF05687.13 PSC72748.1 - 0.1 13.0 0.0 0.17 12.2 0.0 1.3 1 0 0 1 1 1 0 BES1/BZR1 plant transcription factor, N-terminal SMP PF04927.12 PSC72749.1 - 1.5e-05 25.3 8.8 2.2e-05 24.8 8.8 1.2 1 0 0 1 1 1 1 Seed maturation protein Ifi-6-16 PF06140.13 PSC72749.1 - 0.022 14.6 7.9 0.025 14.5 7.9 1.1 1 0 0 1 1 1 0 Interferon-induced 6-16 family DUF615 PF04751.14 PSC72750.1 - 3.5e-27 95.3 11.1 5.5e-27 94.6 10.7 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF615) ABC2_membrane PF01061.24 PSC72751.1 - 3.7e-33 114.7 19.6 3.7e-33 114.7 19.6 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 PSC72751.1 - 7.1e-14 52.5 0.5 5.7e-13 49.6 0.0 2.3 2 1 0 2 2 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PSC72751.1 - 0.0032 16.6 21.1 0.0046 16.1 21.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PSC72751.1 - 0.012 15.5 0.0 1.4 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PSC72751.1 - 0.024 15.0 0.4 0.056 13.8 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 PSC72751.1 - 0.026 14.3 0.1 0.069 12.9 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 PSC72751.1 - 0.043 13.4 0.1 0.087 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PSC72751.1 - 0.14 12.4 0.2 0.29 11.4 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 PSC72751.1 - 0.15 12.6 0.1 0.31 11.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 PSC72751.1 - 0.17 12.3 0.3 7.1 7.1 0.4 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 PSC72751.1 - 0.26 11.2 0.1 0.47 10.3 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase ABC2_membrane PF01061.24 PSC72752.1 - 3.6e-33 114.8 19.6 3.6e-33 114.8 19.6 1.8 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 PSC72752.1 - 5.9e-14 52.7 0.3 5.5e-13 49.6 0.0 2.3 2 1 0 2 2 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PSC72752.1 - 0.003 16.7 21.1 0.0044 16.2 21.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PSC72752.1 - 0.012 15.5 0.0 1.3 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 PSC72752.1 - 0.015 15.7 0.2 0.054 13.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 PSC72752.1 - 0.025 14.3 0.1 0.068 12.9 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 PSC72752.1 - 0.042 13.4 0.1 0.085 12.4 0.1 1.4 1 0 0 1 1 1 0 AAA domain TetR_C_20 PF17925.1 PSC72752.1 - 0.049 14.0 0.3 0.16 12.3 0.1 1.9 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain AAA_22 PF13401.6 PSC72752.1 - 0.14 12.4 0.2 0.31 11.3 0.2 1.6 1 1 0 1 1 1 0 AAA domain AAA_23 PF13476.6 PSC72752.1 - 0.14 12.6 0.1 0.3 11.5 0.0 1.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 PSC72752.1 - 0.16 12.4 0.3 6.9 7.1 0.4 2.4 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 PSC72752.1 - 0.25 11.2 0.1 0.46 10.4 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase SCP2 PF02036.17 PSC72753.1 - 2.4e-24 85.7 0.4 2.9e-24 85.5 0.4 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 PSC72753.1 - 1.1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 PSC72753.1 - 0.018 15.4 0.0 0.021 15.2 0.0 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain SCP2 PF02036.17 PSC72754.1 - 2.4e-24 85.7 0.4 2.9e-24 85.5 0.4 1.1 1 0 0 1 1 1 1 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 PSC72754.1 - 1.1e-05 25.7 0.0 1.4e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal SCP2_2 PF13530.6 PSC72754.1 - 0.018 15.4 0.0 0.021 15.2 0.0 1.2 1 0 0 1 1 1 0 Sterol carrier protein domain PAP_PilO PF06864.12 PSC72755.1 - 0.048 12.5 1.0 0.055 12.3 1.0 1.0 1 0 0 1 1 1 0 Pilin accessory protein (PilO) DUF3181 PF11378.8 PSC72755.1 - 0.058 13.7 0.4 0.071 13.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) UDPGP PF01704.18 PSC72756.1 - 1.4e-05 24.0 0.0 0.00021 20.1 0.0 2.0 2 0 0 2 2 2 2 UTP--glucose-1-phosphate uridylyltransferase GatB_N PF02934.15 PSC72757.1 - 6.4e-111 370.1 0.0 8.8e-111 369.7 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 PSC72757.1 - 3.6e-45 153.5 0.0 5.5e-45 152.9 0.0 1.3 1 0 0 1 1 1 1 GatB domain Nse4_C PF08743.10 PSC72758.1 - 4.7e-23 81.2 0.1 4.7e-23 81.2 0.1 4.6 2 1 0 2 2 2 1 Nse4 C-terminal Ribosomal_L27 PF01016.19 PSC72759.1 - 7.2e-35 118.9 0.4 1.1e-34 118.3 0.4 1.3 1 0 0 1 1 1 1 Ribosomal L27 protein PIN_4 PF13638.6 PSC72760.1 - 0.00039 20.7 0.0 0.00076 19.8 0.0 1.5 1 0 0 1 1 1 1 PIN domain LRR_6 PF13516.6 PSC72760.1 - 0.002 18.1 0.0 1.8 8.8 0.0 2.8 2 0 0 2 2 2 2 Leucine Rich repeat Chloroa_b-bind PF00504.21 PSC72761.1 - 4.6e-49 167.0 0.0 9.3e-49 166.0 0.0 1.5 1 0 0 1 1 1 1 Chlorophyll A-B binding protein GST_N_2 PF13409.6 PSC72761.1 - 1.5e-10 41.3 0.0 3e-10 40.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PSC72761.1 - 2.4e-10 40.3 1.7 1e-09 38.3 0.1 2.8 3 1 0 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PSC72761.1 - 5.9e-06 26.4 0.0 1.3e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PSC72761.1 - 0.0031 17.7 0.0 0.0061 16.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ABC_membrane PF00664.23 PSC72762.1 - 3.5e-120 400.8 30.7 2.1e-63 214.5 12.4 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PSC72762.1 - 9.2e-71 236.7 0.0 1.6e-34 119.3 0.0 2.5 2 0 0 2 2 2 2 ABC transporter Pkinase PF00069.25 PSC72762.1 - 5.7e-48 163.6 0.0 9.4e-48 162.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC72762.1 - 8e-20 71.2 0.0 1.3e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SMC_N PF02463.19 PSC72762.1 - 1.8e-16 60.3 0.0 1.8e-05 24.3 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PSC72762.1 - 6.4e-08 33.2 1.8 0.0015 19.0 0.0 3.4 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.6 PSC72762.1 - 9.5e-08 31.7 0.7 0.015 15.0 0.1 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 PSC72762.1 - 6.3e-07 28.5 1.3 0.0094 14.8 0.2 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 PSC72762.1 - 7.9e-07 28.6 0.5 0.0052 16.1 0.0 3.2 4 0 0 4 4 3 2 Zeta toxin RsgA_GTPase PF03193.16 PSC72762.1 - 1.6e-05 24.9 0.0 0.08 12.8 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_30 PF13604.6 PSC72762.1 - 8.3e-05 22.4 3.7 0.11 12.2 0.3 3.4 2 2 0 2 2 2 2 AAA domain AAA PF00004.29 PSC72762.1 - 0.00042 20.8 0.8 3.7 8.0 0.0 3.7 3 1 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 PSC72762.1 - 0.00047 19.7 0.0 0.99 8.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_22 PF13401.6 PSC72762.1 - 0.00097 19.4 3.1 1.1 9.5 0.1 3.5 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 PSC72762.1 - 0.00099 19.3 3.3 1.8 8.8 0.2 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit DUF815 PF05673.13 PSC72762.1 - 0.0015 17.8 0.0 0.11 11.6 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) G-alpha PF00503.20 PSC72762.1 - 0.0016 17.7 0.0 1 8.4 0.0 2.4 2 0 0 2 2 2 2 G-protein alpha subunit AAA_15 PF13175.6 PSC72762.1 - 0.0017 18.2 0.0 2.1 8.0 0.0 2.8 3 0 0 3 3 3 1 AAA ATPase domain APS_kinase PF01583.20 PSC72762.1 - 0.002 18.0 0.1 1.7 8.5 0.0 2.7 2 0 0 2 2 2 1 Adenylylsulphate kinase DUF3987 PF13148.6 PSC72762.1 - 0.0023 17.0 0.0 0.11 11.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3987) AAA_25 PF13481.6 PSC72762.1 - 0.0049 16.5 0.4 4.3 6.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_23 PF13476.6 PSC72762.1 - 0.0051 17.3 1.8 2.3 8.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.14 PSC72762.1 - 0.0056 16.7 1.0 7.1 6.6 0.0 3.6 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 PSC72762.1 - 0.0074 16.1 0.0 5.6 6.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF87 PF01935.17 PSC72762.1 - 0.0084 16.2 1.0 4.1 7.4 0.2 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain Kdo PF06293.14 PSC72762.1 - 0.039 13.3 0.0 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_33 PF13671.6 PSC72762.1 - 0.041 14.0 0.0 8.4 6.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 PSC72762.1 - 0.042 13.8 0.2 14 5.6 0.0 2.7 2 0 0 2 2 2 0 NACHT domain MMR_HSR1 PF01926.23 PSC72762.1 - 0.042 13.9 0.1 15 5.7 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase Mg_chelatase PF01078.21 PSC72762.1 - 0.045 13.1 0.0 8.8 5.6 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_18 PF13238.6 PSC72762.1 - 0.062 13.8 0.1 34 5.0 0.0 3.4 3 0 0 3 3 3 0 AAA domain SRP54 PF00448.22 PSC72762.1 - 0.082 12.5 0.0 3.3 7.3 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Sigma54_activat PF00158.26 PSC72762.1 - 0.12 12.1 0.0 22 4.7 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain KAP_NTPase PF07693.14 PSC72762.1 - 0.14 11.4 0.0 15 4.7 0.0 2.5 2 0 0 2 2 2 0 KAP family P-loop domain PRK PF00485.18 PSC72762.1 - 0.16 11.7 0.1 25 4.5 0.0 2.6 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF4234 PF14018.6 PSC72762.1 - 0.18 12.0 1.5 3 8.0 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) AAA_24 PF13479.6 PSC72762.1 - 0.19 11.4 0.4 24 4.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF4191 PF13829.6 PSC72762.1 - 9.3 5.5 8.9 1.3 8.4 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4191) CCT PF06203.14 PSC72763.1 - 1.4e-10 41.1 6.4 2.4e-10 40.3 6.4 1.4 1 0 0 1 1 1 1 CCT motif Response_reg PF00072.24 PSC72763.1 - 1e-06 28.9 0.0 2.3e-06 27.7 0.0 1.5 1 0 0 1 1 1 1 Response regulator receiver domain SelP_N PF04592.14 PSC72763.1 - 0.74 9.2 4.1 3.2 7.1 4.1 2.1 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Tim17 PF02466.19 PSC72764.1 - 2e-30 105.4 12.5 2.8e-30 105.0 12.5 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Lar_N PF09861.9 PSC72764.1 - 0.0031 16.7 0.0 0.0042 16.3 0.0 1.2 1 0 0 1 1 1 1 Lactate racemase N-terminal domain Longin PF13774.6 PSC72765.1 - 2.2e-25 88.5 0.1 3.3e-25 87.9 0.1 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 PSC72765.1 - 1.1e-16 60.4 0.3 1.1e-16 60.4 0.3 1.6 2 0 0 2 2 2 1 Synaptobrevin DUF2924 PF11149.8 PSC72765.1 - 0.02 15.3 0.1 0.032 14.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) RNA_ligase PF09414.10 PSC72765.1 - 0.079 13.3 0.0 0.098 13.0 0.0 1.2 1 0 0 1 1 1 0 RNA ligase IMUP PF15761.5 PSC72766.1 - 0.07 13.8 0.4 0.07 13.8 0.4 1.8 2 0 0 2 2 2 0 Immortalisation up-regulated protein Chorion_3 PF05387.11 PSC72766.1 - 2.1 7.9 8.1 1.6 8.3 0.3 2.3 2 0 0 2 2 2 0 Chorion family 3 Rep_fac-A_3 PF08661.11 PSC72767.1 - 6.2e-18 65.1 0.0 8e-18 64.7 0.0 1.0 1 0 0 1 1 1 1 Replication factor A protein 3 SNARE_assoc PF09335.11 PSC72768.1 - 3.2e-20 72.8 2.7 8e-20 71.5 2.7 1.7 1 0 0 1 1 1 1 SNARE associated Golgi protein Usp PF00582.26 PSC72768.1 - 9.3e-17 61.9 0.2 3.8e-16 59.9 0.2 2.0 1 1 0 1 1 1 1 Universal stress protein family PAN_4 PF14295.6 PSC72769.1 - 0.0012 18.7 2.6 0.0012 18.7 2.6 2.3 2 0 0 2 2 2 1 PAN domain PAN_1 PF00024.26 PSC72769.1 - 0.05 13.6 1.7 0.089 12.8 0.3 2.0 2 0 0 2 2 2 0 PAN domain PAN_3 PF08277.12 PSC72769.1 - 9.6 6.1 9.8 0.53 10.1 3.6 2.1 3 0 0 3 3 3 0 PAN-like domain RabGAP-TBC PF00566.18 PSC72771.1 - 1.3e-45 155.7 0.0 2.3e-45 154.9 0.0 1.4 1 0 0 1 1 1 1 Rab-GTPase-TBC domain GST_C_6 PF17171.4 PSC72771.1 - 0.056 13.3 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain MAD PF05557.13 PSC72771.1 - 0.14 10.5 3.2 0.22 9.9 3.2 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein AAA_13 PF13166.6 PSC72771.1 - 0.17 10.5 1.3 0.25 10.0 1.3 1.1 1 0 0 1 1 1 0 AAA domain Spc7 PF08317.11 PSC72771.1 - 0.19 10.6 6.6 0.31 9.9 6.6 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein SUIM_assoc PF16619.5 PSC72771.1 - 6.5 6.9 9.7 27 4.9 0.6 3.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 UPF0004 PF00919.20 PSC72772.1 - 3.9e-17 62.1 0.0 9.1e-17 60.9 0.0 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 Radical_SAM PF04055.21 PSC72772.1 - 7.4e-15 55.7 0.0 1.7e-14 54.5 0.0 1.7 1 0 0 1 1 1 1 Radical SAM superfamily BCNT PF07572.12 PSC72773.1 - 2.1e-23 82.2 5.1 3.9e-23 81.3 5.1 1.5 1 0 0 1 1 1 1 Bucentaur or craniofacial development CN_hydrolase PF00795.22 PSC72774.1 - 4.4e-53 180.3 0.0 5.3e-53 180.0 0.0 1.1 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase QRPTase_C PF01729.19 PSC72776.1 - 1.4e-53 181.1 1.5 1.8e-53 180.8 1.5 1.2 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 PSC72776.1 - 2.6e-28 97.9 0.1 5.4e-28 96.9 0.1 1.6 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, N-terminal domain Adap_comp_sub PF00928.21 PSC72777.1 - 1.2e-47 162.5 0.0 1.6e-47 162.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family muHD PF10291.9 PSC72777.1 - 6.3e-05 22.5 0.0 0.00093 18.7 0.0 2.0 2 0 0 2 2 2 1 Muniscin C-terminal mu homology domain Clat_adaptor_s PF01217.20 PSC72777.1 - 0.011 15.7 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 0 Clathrin adaptor complex small chain Ribosomal_L4 PF00573.22 PSC72778.1 - 1e-55 188.4 0.0 1.3e-55 188.0 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family GTP_EFTU PF00009.27 PSC72779.1 - 1.2e-59 201.1 0.1 1.6e-59 200.7 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 PSC72779.1 - 4.5e-30 104.2 0.0 1.2e-29 102.9 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 PSC72779.1 - 1.5e-18 66.9 5.9 3.5e-18 65.8 5.9 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PSC72779.1 - 1.9e-05 24.7 0.0 3.6e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase cobW PF02492.19 PSC72779.1 - 0.0093 15.6 0.1 0.04 13.5 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.9 PSC72779.1 - 0.012 15.3 0.1 3.5 7.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 PSC72779.1 - 0.021 14.7 0.1 0.096 12.6 0.0 2.0 1 1 1 2 2 2 0 RsgA GTPase AAA_2 PF07724.14 PSC72780.1 - 2.2e-55 187.4 0.5 2.4e-52 177.5 0.0 3.5 3 0 0 3 3 3 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 PSC72780.1 - 1.5e-34 118.1 1.3 1.5e-34 118.1 1.3 3.2 3 0 0 3 3 3 1 AAA lid domain AAA PF00004.29 PSC72780.1 - 1.6e-26 93.3 1.5 1e-13 51.9 0.0 3.5 4 0 0 4 4 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 PSC72780.1 - 1.1e-21 76.6 1.0 7.1e-21 74.1 0.1 3.0 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 PSC72780.1 - 2.1e-18 66.7 1.0 4.8e-13 49.3 0.0 4.0 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) Clp_N PF02861.20 PSC72780.1 - 8.2e-13 48.3 7.6 1.2e-06 28.6 0.9 4.1 4 0 0 4 4 2 2 Clp amino terminal domain, pathogenicity island component AAA_16 PF13191.6 PSC72780.1 - 3e-11 44.0 13.2 2.6e-06 27.9 0.1 5.7 5 2 0 7 7 6 2 AAA ATPase domain AAA_22 PF13401.6 PSC72780.1 - 3.5e-10 40.3 3.2 0.00061 20.1 0.0 5.1 3 2 1 4 4 4 2 AAA domain Sigma54_activat PF00158.26 PSC72780.1 - 3.5e-09 36.6 0.2 5.9e-06 26.1 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_23 PF13476.6 PSC72780.1 - 3.5e-08 34.2 5.5 0.063 13.8 0.0 3.7 3 0 0 3 3 3 2 AAA domain IstB_IS21 PF01695.17 PSC72780.1 - 1.3e-07 31.6 0.7 0.013 15.3 0.0 3.0 3 0 0 3 3 2 2 IstB-like ATP binding protein AAA_7 PF12775.7 PSC72780.1 - 5.9e-07 29.2 0.0 0.0024 17.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_14 PF13173.6 PSC72780.1 - 7.9e-07 29.2 0.1 0.043 13.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain ATPase_2 PF01637.18 PSC72780.1 - 1.8e-06 28.1 0.2 0.2 11.5 0.1 4.1 3 1 1 4 4 4 1 ATPase domain predominantly from Archaea TniB PF05621.11 PSC72780.1 - 3.2e-06 26.7 3.3 0.0053 16.2 0.1 4.1 3 1 0 3 3 3 1 Bacterial TniB protein Mg_chelatase PF01078.21 PSC72780.1 - 1e-05 25.1 0.6 0.02 14.3 0.2 3.6 2 2 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 PSC72780.1 - 5.9e-05 22.9 0.0 0.17 11.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 PSC72780.1 - 7.3e-05 23.3 5.2 0.025 15.1 0.1 4.0 3 2 0 3 3 2 1 AAA domain RNA_helicase PF00910.22 PSC72780.1 - 9.6e-05 22.7 0.4 0.4 11.1 0.0 3.2 3 0 0 3 3 3 1 RNA helicase Roc PF08477.13 PSC72780.1 - 0.00011 22.4 0.0 0.72 10.1 0.0 2.7 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 PSC72780.1 - 0.00032 20.7 0.0 0.81 9.6 0.0 3.3 2 1 1 3 3 3 1 RsgA GTPase NACHT PF05729.12 PSC72780.1 - 0.00037 20.5 0.0 0.2 11.6 0.0 2.8 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 PSC72780.1 - 0.0004 20.2 0.1 2 8.1 0.1 3.5 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.6 PSC72780.1 - 0.00069 19.8 0.2 0.55 10.4 0.0 3.5 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 PSC72780.1 - 0.00088 19.8 1.1 0.24 11.9 0.0 3.2 3 0 0 3 3 2 1 ABC transporter DUF815 PF05673.13 PSC72780.1 - 0.00091 18.5 0.0 0.71 9.0 0.0 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) TsaE PF02367.17 PSC72780.1 - 0.0011 18.9 0.2 2.1 8.4 0.1 3.2 3 0 0 3 3 3 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 PSC72780.1 - 0.0013 19.0 4.7 1.7 8.9 0.0 4.3 5 1 0 5 5 4 2 AAA domain TIP49 PF06068.13 PSC72780.1 - 0.0016 17.7 1.9 2.8 7.1 0.0 3.3 2 1 0 3 3 3 2 TIP49 P-loop domain AAA_25 PF13481.6 PSC72780.1 - 0.0025 17.4 5.6 0.26 10.8 0.2 3.7 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.11 PSC72780.1 - 0.0028 17.5 0.9 2.1 8.2 0.1 3.8 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 PSC72780.1 - 0.0031 17.2 0.0 1.2 8.9 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain ResIII PF04851.15 PSC72780.1 - 0.0033 17.4 0.1 0.54 10.2 0.0 3.7 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit RuvB_N PF05496.12 PSC72780.1 - 0.0047 16.7 4.5 1.6 8.5 0.0 4.5 4 1 0 4 4 3 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 PSC72780.1 - 0.0062 15.8 0.2 0.59 9.4 0.0 3.1 3 0 0 3 3 3 1 Zeta toxin DNA_pol3_delta2 PF13177.6 PSC72780.1 - 0.0075 16.1 0.0 0.17 11.7 0.0 2.7 1 1 0 1 1 1 1 DNA polymerase III, delta subunit NTPase_1 PF03266.15 PSC72780.1 - 0.011 15.7 0.8 2.9 7.8 0.1 3.5 4 0 0 4 4 2 0 NTPase AAA_19 PF13245.6 PSC72780.1 - 0.023 15.1 1.9 1.7 8.9 0.2 3.4 4 1 0 4 4 2 0 AAA domain CorA PF01544.18 PSC72780.1 - 0.024 14.0 5.6 0.05 12.9 5.6 1.6 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein SRP54 PF00448.22 PSC72780.1 - 0.029 14.0 0.3 2 8.0 0.0 3.1 3 0 0 3 3 2 0 SRP54-type protein, GTPase domain PhoH PF02562.16 PSC72780.1 - 0.033 13.6 0.0 1.7 8.1 0.0 3.1 3 0 0 3 3 2 0 PhoH-like protein DnaB_C PF03796.15 PSC72780.1 - 0.043 13.2 0.0 2.2 7.5 0.0 2.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain MMR_HSR1 PF01926.23 PSC72780.1 - 0.13 12.4 0.2 16 5.6 0.0 3.3 3 1 0 3 3 2 0 50S ribosome-binding GTPase DUF3500 PF12006.8 PSC72780.1 - 0.23 10.9 0.7 0.59 9.6 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3500) ATPase PF06745.13 PSC72780.1 - 0.42 9.9 4.1 2.4 7.4 1.0 3.4 4 0 0 4 4 3 0 KaiC DUF1525 PF07511.11 PSC72780.1 - 0.89 9.7 7.2 0.21 11.7 0.4 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1525) FAM76 PF16046.5 PSC72780.1 - 1.7 7.9 4.9 4.1 6.7 4.9 1.6 1 0 0 1 1 1 0 FAM76 protein DUF87 PF01935.17 PSC72780.1 - 2.1 8.4 7.3 10 6.1 0.0 3.3 3 0 0 3 3 3 0 Helicase HerA, central domain Sas10_Utp3 PF04000.15 PSC72780.1 - 2.9 8.6 6.1 0.74 10.5 0.6 2.9 3 0 0 3 3 2 0 Sas10/Utp3/C1D family Med9 PF07544.13 PSC72780.1 - 4.2 7.5 12.8 0.29 11.3 6.1 2.5 2 1 0 2 2 1 0 RNA polymerase II transcription mediator complex subunit 9 Adap_comp_sub PF00928.21 PSC72781.1 - 1.1e-87 293.8 0.0 4.2e-87 291.9 0.0 1.9 2 0 0 2 2 2 1 Adaptor complexes medium subunit family SPT16 PF08644.11 PSC72781.1 - 1.2e-48 165.1 0.2 6.4e-48 162.8 0.0 2.2 2 0 0 2 2 2 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 PSC72781.1 - 6.1e-38 130.2 0.0 2.5e-37 128.1 0.0 2.1 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 PSC72781.1 - 1.3e-28 100.1 0.1 2.2e-28 99.4 0.1 1.4 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 PSC72781.1 - 7.7e-13 48.7 0.1 1.9e-12 47.4 0.1 1.7 1 0 0 1 1 1 1 Histone chaperone Rttp106-like PEMT PF04191.13 PSC72781.1 - 1.5e-10 41.4 0.0 3.9e-10 40.1 0.0 1.7 1 0 0 1 1 1 1 Phospholipid methyltransferase Clat_adaptor_s PF01217.20 PSC72781.1 - 1.7e-08 34.5 0.1 4.2e-08 33.2 0.1 1.6 1 0 0 1 1 1 1 Clathrin adaptor complex small chain ICMT PF04140.14 PSC72781.1 - 0.0016 18.8 0.0 0.0034 17.8 0.0 1.6 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family AP_endonuc_2 PF01261.24 PSC72781.1 - 0.013 15.0 0.2 2.8 7.3 0.1 2.6 2 0 0 2 2 2 0 Xylose isomerase-like TIM barrel NTS_2 PF15448.6 PSC72781.1 - 0.059 13.8 0.2 0.059 13.8 0.2 2.2 2 0 0 2 2 2 0 N-terminal segments of P. falciparum erythrocyte membrane protein DUF1295 PF06966.12 PSC72781.1 - 0.09 12.3 0.0 0.16 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1295) Rad60-SLD PF11976.8 PSC72782.1 - 1.2e-22 79.5 0.0 1.5e-22 79.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 PSC72782.1 - 1.3e-11 44.1 0.0 1.6e-11 43.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Cobl PF09469.10 PSC72782.1 - 0.0052 17.0 0.0 0.0061 16.8 0.0 1.1 1 0 0 1 1 1 1 Cordon-bleu ubiquitin-like domain DUF5010_C PF18099.1 PSC72782.1 - 0.027 14.6 0.0 0.048 13.8 0.0 1.4 1 1 0 1 1 1 0 DUF5010 C-terminal domain RabGAP-TBC PF00566.18 PSC72783.1 - 9.8e-23 80.9 0.0 1.3e-22 80.6 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Xpo1 PF08389.12 PSC72785.1 - 0.0016 18.6 0.0 0.023 14.8 0.0 2.4 2 0 0 2 2 2 1 Exportin 1-like protein zf-MYND PF01753.18 PSC72786.1 - 2.3e-07 30.8 10.2 3.8e-07 30.1 10.2 1.4 1 0 0 1 1 1 1 MYND finger XRCC4 PF06632.12 PSC72786.1 - 1.6 7.5 3.6 2.2 7.1 3.6 1.1 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF4345 PF14248.6 PSC72787.1 - 0.034 14.0 2.3 0.17 11.8 2.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4345) Barttin PF15462.6 PSC72788.1 - 0.1 12.3 0.0 0.11 12.2 0.0 1.0 1 0 0 1 1 1 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) PQ-loop PF04193.14 PSC72789.1 - 1.2e-35 121.1 3.9 7e-19 67.4 0.0 2.4 2 0 0 2 2 2 2 PQ loop repeat SelP_N PF04592.14 PSC72789.1 - 0.35 10.2 2.6 0.5 9.7 2.6 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region MtN3_slv PF03083.16 PSC72789.1 - 0.36 10.9 3.8 4.7 7.3 0.2 2.3 2 0 0 2 2 2 0 Sugar efflux transporter for intercellular exchange DUF2076 PF09849.9 PSC72789.1 - 1.8 8.5 10.6 2.7 8.0 10.6 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) RRM_1 PF00076.22 PSC72790.1 - 4.5e-39 132.1 0.1 1.4e-14 53.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 PSC72790.1 - 6.1e-17 62.5 3.5 1e-16 61.8 0.1 2.6 2 0 0 2 2 2 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 PSC72790.1 - 2.6e-05 24.0 0.0 0.021 14.6 0.0 3.2 3 0 0 3 3 3 1 Occluded RNA-recognition motif Spt5-NGN PF03439.13 PSC72790.1 - 0.0082 16.0 0.1 0.02 14.8 0.0 1.8 2 0 0 2 2 2 1 Early transcription elongation factor of RNA pol II, NGN section RSRP PF17069.5 PSC72790.1 - 0.11 12.0 33.0 0.19 11.3 33.0 1.3 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 RL PF17797.1 PSC72790.1 - 0.14 12.1 0.0 0.3 11.0 0.0 1.5 1 0 0 1 1 1 0 RL domain Apt1 PF10351.9 PSC72790.1 - 0.26 10.1 3.6 0.32 9.8 3.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Pkinase_Tyr PF07714.17 PSC72792.1 - 4.2e-43 147.5 0.0 1.1e-42 146.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC72792.1 - 1.1e-41 143.0 0.0 2.3e-41 141.9 0.0 1.4 1 1 0 1 1 1 1 Protein kinase domain PAN_4 PF14295.6 PSC72792.1 - 1.5e-05 24.8 8.4 0.00093 19.1 6.1 2.6 2 0 0 2 2 2 2 PAN domain PAN_1 PF00024.26 PSC72792.1 - 0.0002 21.2 0.9 0.0033 17.4 1.4 2.3 2 0 0 2 2 2 1 PAN domain Pkinase_fungal PF17667.1 PSC72792.1 - 0.0016 17.3 0.0 0.0024 16.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Ribosomal_L22 PF00237.19 PSC72793.1 - 1.9e-39 134.1 0.1 2.8e-39 133.5 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e DUF1609 PF07753.11 PSC72793.1 - 0.043 13.3 1.0 0.72 9.3 1.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1609) VEG PF06257.11 PSC72793.1 - 0.91 9.6 2.7 1.1 9.4 0.2 2.2 2 1 1 3 3 3 0 Biofilm formation stimulator VEG DUF4336 PF14234.6 PSC72794.1 - 3.2e-98 328.9 1.1 1.6e-95 320.0 1.1 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4336) Barwin PF00967.17 PSC72794.1 - 2.2e-26 92.1 0.4 5.6e-26 90.7 0.4 1.7 1 0 0 1 1 1 1 Barwin family ESP PF16590.5 PSC72794.1 - 0.25 11.6 0.4 0.59 10.4 0.4 1.5 1 0 0 1 1 1 0 Exocrine gland-secreting peptide BSP_II PF05432.11 PSC72794.1 - 4.7 6.8 16.9 8.3 6.0 16.9 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) HhH-GPD PF00730.25 PSC72795.1 - 0.00033 21.1 0.0 0.00061 20.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HhH-GPD PF00730.25 PSC72796.1 - 0.00033 21.1 0.0 0.00061 20.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein PhetRS_B1 PF18262.1 PSC72797.1 - 6.3 7.1 7.9 16 5.8 2.4 2.7 1 1 1 2 2 2 0 Phe-tRNA synthetase beta subunit B1 domain Ank_2 PF12796.7 PSC72798.1 - 1.3e-15 57.7 2.1 1.6e-10 41.4 0.4 2.3 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC72798.1 - 1.1e-11 44.7 7.0 0.0015 18.8 0.4 3.8 2 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC72798.1 - 1.5e-10 41.4 4.2 7.7e-05 23.2 0.5 3.6 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PSC72798.1 - 3.4e-08 33.6 11.3 0.0021 18.4 0.4 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 PSC72798.1 - 3.5e-06 26.9 7.7 0.15 12.7 0.1 5.7 5 1 0 5 5 5 1 Ankyrin repeat Transp_cyt_pur PF02133.15 PSC72799.1 - 9.8e-81 271.8 36.1 1.3e-80 271.4 36.1 1.1 1 0 0 1 1 1 1 Permease for cytosine/purines, uracil, thiamine, allantoin LRR_8 PF13855.6 PSC72799.1 - 1.5e-11 43.9 1.7 0.00096 18.9 0.0 4.0 2 1 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 PSC72799.1 - 3.7e-09 36.7 3.0 0.0032 17.8 0.0 5.3 4 1 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PSC72799.1 - 1.4e-05 24.9 1.9 1.2 9.9 0.0 5.6 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_9 PF14580.6 PSC72799.1 - 0.00011 21.7 0.0 0.00044 19.8 0.0 1.8 1 1 1 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 PSC72799.1 - 0.01 15.8 1.0 11 6.3 0.1 4.5 3 0 0 3 3 3 0 Leucine Rich repeat DUF444 PF04285.12 PSC72800.1 - 0.011 14.8 0.0 0.014 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF444) SNF2_N PF00176.23 PSC72801.1 - 3e-76 256.4 0.4 6.8e-76 255.3 0.4 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 PSC72801.1 - 1.3e-47 160.6 3.7 1.3e-47 160.6 3.7 2.6 3 0 0 3 3 3 1 SLIDE Helicase_C PF00271.31 PSC72801.1 - 1.4e-20 73.7 0.0 4.1e-19 69.0 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC72801.1 - 7.3e-12 45.6 0.7 3.6e-11 43.4 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit HAND PF09110.11 PSC72801.1 - 5.3e-09 36.8 4.7 5.3e-09 36.8 4.7 3.1 3 0 0 3 3 1 1 HAND DEAD PF00270.29 PSC72801.1 - 3.1e-07 30.3 0.0 1.7e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Myb_DNA-binding PF00249.31 PSC72801.1 - 1.9e-05 24.7 4.8 0.042 14.0 0.1 3.8 3 0 0 3 3 3 2 Myb-like DNA-binding domain DBINO PF13892.6 PSC72801.1 - 8.5e-05 22.9 5.5 8.5e-05 22.9 5.5 3.5 3 0 0 3 3 3 1 DNA-binding domain SWI2_SNF2 PF18766.1 PSC72801.1 - 0.00047 19.9 0.0 0.0012 18.5 0.0 1.7 1 0 0 1 1 1 1 SWI2/SNF2 ATPase DUF1086 PF06461.11 PSC72801.1 - 0.0036 17.2 0.1 0.013 15.4 0.1 1.9 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) HDA2-3 PF11496.8 PSC72801.1 - 0.013 14.7 0.0 0.039 13.1 0.0 1.8 1 1 0 1 1 1 0 Class II histone deacetylase complex subunits 2 and 3 AAA_14 PF13173.6 PSC72801.1 - 0.067 13.2 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain Sec39 PF08314.11 PSC72802.1 - 8.8e-15 54.2 0.0 2.9e-05 22.7 0.0 3.3 2 1 1 3 3 3 3 Secretory pathway protein Sec39 dsDNA_bind PF01984.20 PSC72802.1 - 0.092 13.0 3.7 0.11 12.8 0.3 3.0 2 0 0 2 2 2 0 Double-stranded DNA-binding domain EcKinase PF02958.20 PSC72803.1 - 1.8e-16 60.4 0.0 1.2e-08 34.6 0.0 2.1 2 0 0 2 2 2 2 Ecdysteroid kinase APH PF01636.23 PSC72803.1 - 1.3e-05 25.2 2.2 3.4e-05 23.9 2.2 1.7 1 0 0 1 1 1 1 Phosphotransferase enzyme family NUDIX PF00293.28 PSC72803.1 - 2.8e-05 24.2 0.0 5.3e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Rep_fac_C PF08542.11 PSC72804.1 - 1.2e-24 86.5 0.0 4e-24 84.8 0.0 1.9 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 PSC72804.1 - 3.1e-14 53.5 0.0 4.7e-14 52.9 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 PSC72804.1 - 2.2e-12 47.0 0.0 3.2e-10 40.0 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase III, delta subunit AAA_14 PF13173.6 PSC72804.1 - 2.5e-06 27.6 0.0 3.6e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PSC72804.1 - 3.7e-06 27.4 0.0 0.00082 19.8 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PSC72804.1 - 5.6e-06 26.7 0.1 0.024 14.9 0.0 2.5 1 1 1 2 2 2 2 AAA domain Rad17 PF03215.15 PSC72804.1 - 2.5e-05 24.3 0.0 5e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Rad17 P-loop domain Mg_chelatase PF01078.21 PSC72804.1 - 3.9e-05 23.1 0.0 0.00071 19.0 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 PSC72804.1 - 7e-05 22.7 0.0 0.00018 21.3 0.0 1.7 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 PSC72804.1 - 0.00017 21.5 0.0 0.00024 21.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 PSC72804.1 - 0.00026 20.8 0.0 0.00045 20.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 PSC72804.1 - 0.0006 19.6 0.0 0.0015 18.3 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_19 PF13245.6 PSC72804.1 - 0.0007 19.9 0.2 0.0063 16.9 0.2 2.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 PSC72804.1 - 0.0012 18.8 0.0 0.0026 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_25 PF13481.6 PSC72804.1 - 0.0021 17.7 0.0 0.0098 15.5 0.0 2.0 2 1 1 3 3 3 1 AAA domain TniB PF05621.11 PSC72804.1 - 0.0027 17.1 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 2 Bacterial TniB protein AAA_30 PF13604.6 PSC72804.1 - 0.0078 15.9 0.1 0.039 13.7 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PSC72804.1 - 0.0081 16.7 0.0 0.014 15.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 PSC72804.1 - 0.0099 15.7 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_assoc_2 PF16193.5 PSC72804.1 - 0.01 16.2 0.0 0.029 14.7 0.0 1.8 2 0 0 2 2 1 0 AAA C-terminal domain RNA_helicase PF00910.22 PSC72804.1 - 0.012 16.0 0.0 0.052 13.9 0.0 2.1 1 1 0 1 1 1 0 RNA helicase NTPase_1 PF03266.15 PSC72804.1 - 0.014 15.3 0.3 0.21 11.5 0.1 2.3 1 1 1 2 2 2 0 NTPase DEAD PF00270.29 PSC72804.1 - 0.018 14.8 0.2 1.2 8.9 0.0 2.6 1 1 2 3 3 3 0 DEAD/DEAH box helicase AAA_28 PF13521.6 PSC72804.1 - 0.024 14.9 0.0 0.04 14.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 PSC72804.1 - 0.025 13.7 0.0 0.051 12.6 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein DNA_pol3_delta PF06144.13 PSC72804.1 - 0.032 14.0 0.1 0.048 13.4 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit ABC_tran PF00005.27 PSC72804.1 - 0.042 14.4 0.0 0.1 13.1 0.0 1.5 1 1 0 1 1 1 0 ABC transporter MeaB PF03308.16 PSC72804.1 - 0.05 12.6 0.0 0.12 11.4 0.0 1.5 1 1 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_7 PF12775.7 PSC72804.1 - 0.074 12.6 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region IstB_IS21 PF01695.17 PSC72804.1 - 0.08 12.7 0.0 0.16 11.7 0.0 1.5 1 1 0 1 1 1 0 IstB-like ATP binding protein DUF2075 PF09848.9 PSC72804.1 - 0.19 11.0 0.1 2.1 7.5 0.1 2.1 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) RVT_1 PF00078.27 PSC72806.1 - 6.4e-33 114.1 0.0 1e-32 113.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 PSC72806.1 - 2.6e-05 23.9 0.2 0.00058 19.4 0.1 2.6 2 1 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family DS PF01916.17 PSC72807.1 - 1.3e-127 425.0 0.0 1.6e-127 424.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase UPF0014 PF03649.13 PSC72808.1 - 2e-74 250.0 21.0 2.9e-74 249.5 21.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0014) ABC_tran PF00005.27 PSC72808.1 - 8.2e-22 78.2 0.0 1.6e-21 77.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 PSC72808.1 - 0.00034 21.1 0.1 0.00034 21.1 0.1 3.9 3 1 0 3 3 3 1 AAA ATPase domain AAA_21 PF13304.6 PSC72808.1 - 0.00062 19.7 0.0 0.48 10.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 PSC72808.1 - 0.0037 17.5 0.1 0.016 15.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 PSC72808.1 - 0.02 14.8 0.1 0.041 13.8 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase SR-25 PF10500.9 PSC72808.1 - 0.037 13.6 20.7 0.059 13.0 20.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DNA_topoisoIV PF00521.20 PSC72808.1 - 0.11 11.4 0.0 0.17 10.8 0.0 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A DUF755 PF05501.11 PSC72808.1 - 3.5 7.9 18.8 8.8 6.6 18.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) AP3D1 PF06375.11 PSC72808.1 - 5.8 7.1 11.2 10 6.3 11.2 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 HGTP_anticodon PF03129.20 PSC72809.1 - 6.6e-19 67.9 0.0 1.6e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 PSC72809.1 - 5.2e-12 46.1 0.0 5e-11 42.9 0.0 2.2 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) WHEP-TRS PF00458.20 PSC72809.1 - 2.6e-07 30.7 1.5 8e-07 29.1 1.5 1.8 1 0 0 1 1 1 1 WHEP-TRS domain DUF932 PF06067.11 PSC72809.1 - 0.13 12.0 0.1 0.4 10.4 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF932) C2 PF00168.30 PSC72810.1 - 6.6e-31 106.7 0.0 1.9e-23 82.7 0.0 2.4 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 PSC72810.1 - 8.7e-07 28.6 0.0 0.011 15.2 0.0 2.3 2 0 0 2 2 2 2 Synaptotagmin-like mitochondrial-lipid-binding domain DUF4381 PF14316.6 PSC72810.1 - 0.048 13.9 2.3 0.13 12.4 2.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4381) TPX2_importin PF12214.8 PSC72811.1 - 1.8e-26 93.3 23.4 4.5e-19 69.2 0.1 4.8 4 1 1 5 5 5 4 Cell cycle regulated microtubule associated protein TPX2 PF06886.11 PSC72811.1 - 4.7e-10 39.6 7.3 4.7e-10 39.6 7.3 6.5 7 1 0 7 7 7 1 Targeting protein for Xklp2 (TPX2) ubiquitin PF00240.23 PSC72812.1 - 3.4e-08 33.1 0.0 6.4e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family TPR_19 PF14559.6 PSC72812.1 - 2.3e-06 28.0 22.3 0.019 15.5 5.9 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 PSC72812.1 - 7.6e-06 26.5 7.9 0.0011 19.6 0.2 4.8 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 PSC72812.1 - 0.00014 22.0 3.1 0.2 12.1 0.0 3.3 3 0 0 3 3 2 2 Tetratricopeptide repeat Metal_resist PF13801.6 PSC72812.1 - 0.00037 20.7 5.3 0.00037 20.7 5.3 4.2 2 1 2 4 4 4 1 Heavy-metal resistance TPR_2 PF07719.17 PSC72812.1 - 0.0015 18.5 4.3 3.9 7.8 0.2 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 PSC72812.1 - 0.0019 18.8 18.7 0.19 12.6 1.5 6.1 2 1 4 6 6 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 PSC72812.1 - 0.0076 16.4 3.9 0.72 10.1 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 PSC72812.1 - 0.02 14.5 1.0 0.23 11.2 0.0 2.5 2 0 0 2 2 2 0 TPR repeat Rad60-SLD PF11976.8 PSC72812.1 - 0.033 14.0 0.0 0.064 13.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like TPR_12 PF13424.6 PSC72812.1 - 0.14 12.4 13.1 1.4 9.3 0.7 4.8 3 2 2 5 5 4 0 Tetratricopeptide repeat TPR_20 PF14561.6 PSC72812.1 - 0.16 12.4 10.9 5.4 7.4 1.3 3.8 3 1 1 4 4 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 PSC72812.1 - 0.24 12.1 6.3 0.85 10.4 0.0 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat BTAD PF03704.17 PSC72812.1 - 4.7 7.6 12.0 0.61 10.5 2.4 3.5 3 2 0 3 3 3 0 Bacterial transcriptional activator domain PSI_PsaF PF02507.15 PSC72813.1 - 1.2e-75 253.1 0.6 1.5e-75 252.8 0.0 1.4 2 0 0 2 2 2 1 Photosystem I reaction centre subunit III DUF4179 PF13786.6 PSC72813.1 - 0.11 12.9 0.5 0.22 12.0 0.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) SLBB PF10531.9 PSC72814.1 - 0.15 11.9 3.3 2.6 8.0 0.1 3.0 3 0 0 3 3 3 0 SLBB domain SLBB PF10531.9 PSC72815.1 - 0.16 11.9 3.3 2.6 8.0 0.1 3.0 3 0 0 3 3 3 0 SLBB domain Cpn10 PF00166.21 PSC72816.1 - 1.8e-16 59.9 0.1 2.4e-16 59.5 0.1 1.2 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF3558 PF12079.8 PSC72816.1 - 0.014 15.4 0.1 0.018 15.1 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3558) DXP_reductoisom PF02670.16 PSC72817.1 - 4.3e-46 156.8 0.1 8.4e-46 155.9 0.1 1.5 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase DXP_redisom_C PF08436.12 PSC72817.1 - 1.1e-39 134.4 0.0 2.4e-39 133.4 0.0 1.6 1 0 0 1 1 1 1 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal domain DXPR_C PF13288.6 PSC72817.1 - 1.9e-39 134.5 0.0 3.3e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 DXP reductoisomerase C-terminal domain NAD_binding_3 PF03447.16 PSC72817.1 - 0.16 12.6 0.5 4.1 8.1 0.0 2.8 2 1 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Med27 PF11571.8 PSC72818.1 - 8.8e-07 29.2 0.0 1.7e-06 28.3 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 27 FlgN PF05130.12 PSC72818.1 - 0.028 14.9 1.2 0.09 13.3 1.2 1.8 2 0 0 2 2 2 0 FlgN protein BCAS3 PF12490.8 PSC72818.1 - 0.18 11.3 1.9 0.31 10.5 1.9 1.2 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 FliN_N PF16973.5 PSC72818.1 - 0.53 10.2 5.8 21 5.0 0.8 3.6 3 0 0 3 3 3 0 Flagellar motor switch protein FliN N-terminal PDDEXK_6 PF04720.12 PSC72819.1 - 5.8e-19 68.9 0.2 2e-18 67.2 0.2 1.8 1 1 0 1 1 1 1 PDDEXK-like family of unknown function Rootletin PF15035.6 PSC72820.1 - 0.016 15.2 11.1 0.45 10.5 1.4 2.6 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Spc7 PF08317.11 PSC72820.1 - 0.22 10.4 15.7 0.035 13.0 11.1 2.0 1 1 0 1 1 1 0 Spc7 kinetochore protein PRKG1_interact PF15898.5 PSC72820.1 - 0.58 11.1 11.2 2 9.3 5.1 3.5 2 1 2 4 4 4 0 cGMP-dependent protein kinase interacting domain YabA PF06156.13 PSC72820.1 - 1.5 9.5 3.2 23 5.7 0.3 3.1 1 1 2 3 3 3 0 Initiation control protein YabA DUF812 PF05667.11 PSC72820.1 - 1.7 7.4 8.5 2.6 6.8 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Leu_zip PF15294.6 PSC72820.1 - 1.8 8.0 7.5 2.8 7.4 2.6 2.3 1 1 3 4 4 4 0 Leucine zipper Atg14 PF10186.9 PSC72820.1 - 1.9 7.5 10.7 2.5 7.1 9.8 1.6 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MAD PF05557.13 PSC72820.1 - 2 6.7 12.6 0.15 10.4 7.7 1.6 2 0 0 2 2 2 0 Mitotic checkpoint protein Fez1 PF06818.15 PSC72820.1 - 4.5 7.7 15.9 4.2 7.8 7.8 2.3 1 1 1 2 2 2 0 Fez1 SRP9-21 PF05486.12 PSC72821.1 - 3.9e-11 43.2 8.6 4.2e-11 43.1 0.3 2.9 2 1 0 2 2 2 1 Signal recognition particle 9 kDa protein (SRP9) Use1 PF09753.9 PSC72822.1 - 3.5e-18 66.2 0.0 2e-15 57.2 0.0 2.0 2 0 0 2 2 2 2 Membrane fusion protein Use1 Totivirus_coat PF05518.11 PSC72822.1 - 0.095 10.7 3.8 0.14 10.2 3.8 1.2 1 0 0 1 1 1 0 Totivirus coat protein 2OG-FeII_Oxy_3 PF13640.6 PSC72823.1 - 5.6e-18 65.6 0.0 9.2e-18 64.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 PSC72823.1 - 0.0084 16.6 11.4 0.065 13.8 11.4 2.4 1 1 0 1 1 1 1 ShK domain-like PhyH PF05721.13 PSC72823.1 - 0.082 13.2 0.0 0.14 12.4 0.0 1.4 1 0 0 1 1 1 0 Phytanoyl-CoA dioxygenase (PhyH) SOUL PF04832.12 PSC72824.1 - 5.3e-39 134.1 0.0 6.2e-37 127.3 0.0 2.0 1 1 0 1 1 1 1 SOUL heme-binding protein Alpha-L-AF_C PF06964.12 PSC72825.1 - 2.7e-26 92.7 0.0 8e-26 91.2 0.0 1.8 1 1 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain LRR_8 PF13855.6 PSC72825.1 - 6.2e-12 45.1 3.4 4.6e-07 29.5 0.1 4.3 3 1 3 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 PSC72825.1 - 1.1e-08 35.2 1.5 0.018 15.5 0.0 4.4 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PSC72825.1 - 0.00012 22.1 4.2 6.4 7.7 0.0 5.3 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_9 PF14580.6 PSC72825.1 - 0.0038 16.8 0.0 0.018 14.6 0.0 2.0 2 1 1 3 3 3 1 Leucine-rich repeat LRR_6 PF13516.6 PSC72825.1 - 2 8.6 8.8 20 5.6 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich repeat Alpha-L-AF_C PF06964.12 PSC72826.1 - 3e-26 92.5 0.0 8.8e-26 91.0 0.0 1.7 1 1 0 1 1 1 1 Alpha-L-arabinofuranosidase C-terminal domain LRR_8 PF13855.6 PSC72826.1 - 3.4e-11 42.7 3.5 4.9e-07 29.4 0.1 4.2 3 1 3 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 PSC72826.1 - 1.4e-08 34.8 1.5 0.019 15.4 0.0 4.4 5 1 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PSC72826.1 - 0.00026 21.1 4.9 6.9 7.6 0.0 5.3 5 0 0 5 5 5 2 Leucine Rich Repeat LRR_9 PF14580.6 PSC72826.1 - 0.0042 16.6 0.0 0.019 14.5 0.0 2.0 1 1 1 2 2 2 1 Leucine-rich repeat LRR_6 PF13516.6 PSC72826.1 - 2.7 8.3 8.8 21 5.5 0.1 4.9 5 0 0 5 5 5 0 Leucine Rich repeat Patatin PF01734.22 PSC72827.1 - 1.1e-23 84.5 0.2 3.6e-23 82.8 0.2 1.9 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3336 PF11815.8 PSC72827.1 - 5.3e-09 35.9 0.0 0.0024 17.6 0.0 2.6 2 1 0 2 2 2 2 Domain of unknown function (DUF3336) TFIIA PF03153.13 PSC72827.1 - 0.72 9.8 23.5 1.1 9.2 23.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CMD PF02627.20 PSC72828.1 - 0.0048 16.9 0.4 0.23 11.5 0.1 2.4 2 0 0 2 2 2 2 Carboxymuconolactone decarboxylase family Peptidase_C1 PF00112.23 PSC72829.1 - 1.5e-77 260.6 0.1 2.2e-77 260.1 0.1 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Granulin PF00396.18 PSC72829.1 - 2.8e-11 43.6 23.6 2.8e-11 43.6 23.6 2.5 1 1 1 2 2 2 1 Granulin Inhibitor_I29 PF08246.12 PSC72829.1 - 3.3e-09 37.0 1.3 4.8e-09 36.5 1.3 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PSC72829.1 - 0.0055 15.5 1.2 0.36 9.5 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family DEC-1_N PF04625.13 PSC72829.1 - 1.3 8.0 5.8 2.4 7.1 5.8 1.3 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region NMD3 PF04981.13 PSC72831.1 - 1.1e-79 267.4 6.8 1.5e-79 266.9 6.8 1.2 1 0 0 1 1 1 1 NMD3 family CBM_48 PF02922.18 PSC72831.1 - 0.00035 20.9 0.0 0.0033 17.7 0.0 2.3 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) DZR PF12773.7 PSC72831.1 - 0.29 11.2 8.2 6.1 7.0 0.2 2.8 1 1 1 2 2 2 0 Double zinc ribbon DUF212 PF02681.14 PSC72832.1 - 3.2e-48 163.1 0.7 3.8e-48 162.8 0.7 1.0 1 0 0 1 1 1 1 Divergent PAP2 family PAP2 PF01569.21 PSC72832.1 - 0.013 15.3 9.3 0.16 11.8 1.4 2.6 2 1 1 3 3 3 0 PAP2 superfamily Gly-zipper_YMGG PF13441.6 PSC72832.1 - 1.2 8.9 6.7 0.52 10.1 0.2 2.6 3 0 0 3 3 3 0 YMGG-like Gly-zipper PhoR PF11808.8 PSC72832.1 - 8.5 6.9 7.2 35 4.9 0.3 3.0 3 0 0 3 3 3 0 Phosphate regulon sensor protein PhoR Gly-zipper_Omp PF13488.6 PSC72832.1 - 9.7 6.3 9.7 1.4 9.0 0.5 2.6 3 0 0 3 3 3 0 Glycine zipper DUF4200 PF13863.6 PSC72833.1 - 9.4e-32 109.9 19.5 9.4e-32 109.9 19.5 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4200) Pescadillo_N PF06732.11 PSC72835.1 - 3.4e-110 367.9 0.0 5.5e-110 367.2 0.0 1.2 1 0 0 1 1 1 1 Pescadillo N-terminus Epimerase PF01370.21 PSC72835.1 - 6.4e-44 150.2 0.0 9.4e-44 149.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PSC72835.1 - 1.9e-25 90.0 0.0 2.2e-24 86.5 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 PSC72835.1 - 3e-09 37.0 0.0 6.4e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 PSC72835.1 - 2.3e-08 33.4 0.0 3.6e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family BRCT_2 PF16589.5 PSC72835.1 - 1.3e-05 25.5 0.0 0.00075 19.9 0.0 2.7 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain Polysacc_synt_2 PF02719.15 PSC72835.1 - 0.00056 19.1 0.0 0.019 14.1 0.1 2.5 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 PSC72835.1 - 0.0035 16.6 0.0 0.11 11.6 0.0 2.3 2 0 0 2 2 2 1 Male sterility protein NmrA PF05368.13 PSC72835.1 - 0.026 14.1 0.0 0.065 12.8 0.0 1.6 1 1 0 1 1 1 0 NmrA-like family JAB PF01398.21 PSC72837.1 - 7.1e-18 64.7 0.0 1.1e-17 64.1 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 PSC72837.1 - 0.00027 20.7 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain PBP PF01161.20 PSC72838.1 - 1.6e-17 64.0 0.0 2.2e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PBP PF01161.20 PSC72839.1 - 9.3e-18 64.8 0.0 1.1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein ribosomal_L24 PF17136.4 PSC72840.1 - 6.1e-18 65.0 0.0 1.3e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 PSC72840.1 - 1.7e-06 27.8 1.3 1.7e-06 27.8 1.3 2.3 2 0 0 2 2 2 1 KOW motif eIF3g PF12353.8 PSC72840.1 - 0.004 17.5 0.0 0.0074 16.7 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit G Serinc PF03348.15 PSC72841.1 - 3.4e-86 289.9 0.7 4.8e-86 289.3 0.7 1.2 1 0 0 1 1 1 1 Serine incorporator (Serinc) Ank_2 PF12796.7 PSC72841.1 - 1.1e-15 58.0 6.9 7.3e-10 39.3 1.6 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC72841.1 - 5.1e-14 52.4 9.1 4.4e-08 33.5 0.9 4.0 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC72841.1 - 2e-13 50.3 14.3 1.3e-07 31.8 0.7 4.7 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC72841.1 - 1.3e-07 31.3 14.1 0.44 11.3 0.1 6.3 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 PSC72841.1 - 7.4e-06 26.2 25.6 0.0023 18.3 1.2 5.8 6 0 0 6 6 6 3 Ankyrin repeat Ras PF00071.22 PSC72842.1 - 1.9e-60 203.1 0.0 2.8e-60 202.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PSC72842.1 - 3e-31 108.1 0.0 4.7e-31 107.5 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMS1_N PF10433.9 PSC72842.1 - 3.9e-17 62.1 0.0 8.4e-17 61.0 0.0 1.4 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Arf PF00025.21 PSC72842.1 - 9e-11 41.5 0.0 1.5e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 PSC72842.1 - 0.00098 19.2 0.0 0.002 18.2 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PSC72842.1 - 0.033 13.6 0.0 0.048 13.0 0.0 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 PSC72842.1 - 0.039 13.5 0.1 0.089 12.3 0.0 1.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PSC72842.1 - 0.19 11.6 0.0 4 7.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase DAP3 PF10236.9 PSC72842.1 - 0.22 10.7 0.0 0.36 10.0 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 TFIIA PF03153.13 PSC72842.1 - 0.51 10.3 4.4 0.95 9.4 4.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PrmA PF06325.13 PSC72845.1 - 2.6e-10 40.2 0.5 1.6e-09 37.6 0.4 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PSC72845.1 - 2.9e-10 40.7 0.1 7.6e-09 36.2 0.1 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC72845.1 - 2.5e-08 33.9 0.0 5.9e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC72845.1 - 3.1e-07 30.3 0.0 8.2e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC72845.1 - 4.2e-07 30.5 0.0 1.2e-05 25.9 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PSC72845.1 - 5.4e-06 26.1 0.1 9.9e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 PSC72845.1 - 2.8e-05 23.6 0.0 4.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 PSC72845.1 - 5e-05 23.1 0.0 8.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 PSC72845.1 - 0.001 19.8 0.0 0.0059 17.3 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 PSC72845.1 - 0.0026 16.7 0.0 0.0039 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.15 PSC72845.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 PSC72845.1 - 0.015 15.3 0.0 0.044 13.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 PSC72845.1 - 0.037 13.3 0.0 0.061 12.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 PSC72845.1 - 0.052 13.3 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_32 PF13679.6 PSC72845.1 - 0.055 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 PSC72846.1 - 2.6e-10 40.2 0.5 1.6e-09 37.6 0.4 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PSC72846.1 - 3e-10 40.7 0.1 7.6e-09 36.2 0.1 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC72846.1 - 2.5e-08 33.9 0.0 5.9e-08 32.7 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC72846.1 - 3.1e-07 30.3 0.0 8.2e-07 28.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC72846.1 - 4.2e-07 30.5 0.0 1.2e-05 25.9 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 PSC72846.1 - 5.4e-06 26.1 0.1 9.9e-06 25.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.20 PSC72846.1 - 2.8e-05 23.6 0.0 4.5e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 PSC72846.1 - 5.1e-05 23.1 0.0 8.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_12 PF08242.12 PSC72846.1 - 0.001 19.8 0.0 0.0059 17.3 0.1 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.11 PSC72846.1 - 0.0026 16.7 0.0 0.0039 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.15 PSC72846.1 - 0.013 15.1 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 PSC72846.1 - 0.015 15.3 0.0 0.044 13.7 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 PSC72846.1 - 0.037 13.4 0.0 0.062 12.6 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 PSC72846.1 - 0.053 13.3 0.0 0.097 12.4 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_32 PF13679.6 PSC72846.1 - 0.055 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Pkinase PF00069.25 PSC72848.1 - 2.1e-56 191.2 0.0 2.6e-56 190.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC72848.1 - 4.3e-27 95.0 0.0 6.3e-27 94.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PSC72848.1 - 0.00082 18.2 0.0 0.0012 17.7 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF4349 PF14257.6 PSC72848.1 - 0.0043 16.5 1.2 0.0082 15.6 1.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4349) Haspin_kinase PF12330.8 PSC72848.1 - 0.0063 15.5 0.0 0.0091 15.0 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Latarcin PF10279.9 PSC72848.1 - 0.027 14.9 0.1 0.086 13.3 0.0 1.8 1 1 0 1 1 1 0 Latarcin precursor APH PF01636.23 PSC72848.1 - 0.17 11.8 3.8 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S30 PF04758.14 PSC72849.1 - 2.3e-30 104.6 9.9 2.5e-30 104.4 9.9 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 THF_DHG_CYH_C PF02882.19 PSC72850.1 - 2e-53 180.0 0.7 6.2e-19 67.9 0.0 3.1 3 0 0 3 3 3 3 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 PSC72850.1 - 9.6e-33 112.9 0.0 1.4e-32 112.4 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain eIF-4B PF06273.11 PSC72851.1 - 2e-30 106.3 97.4 4.3e-16 59.1 32.5 4.8 1 1 2 3 3 3 3 Plant specific eukaryotic initiation factor 4B DUF4407 PF14362.6 PSC72851.1 - 0.21 10.9 8.5 0.35 10.2 8.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GvpG PF05120.12 PSC72851.1 - 2.2 8.3 6.8 2.8 8.0 2.3 2.3 2 0 0 2 2 2 0 Gas vesicle protein G Acyl_transf_3 PF01757.22 PSC72852.1 - 8.8e-19 67.7 26.4 1.1e-18 67.4 26.4 1.1 1 0 0 1 1 1 1 Acyltransferase family DUF2499 PF10693.9 PSC72858.1 - 5.1e-27 94.0 1.3 5.6e-27 93.8 1.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2499) DUF3311 PF11755.8 PSC72858.1 - 0.21 11.6 4.9 0.72 9.8 0.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3311) Acetyltransf_1 PF00583.25 PSC72859.1 - 4.3e-13 49.5 0.0 4.9e-13 49.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PSC72859.1 - 3.4e-07 30.6 0.0 4.7e-07 30.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PSC72859.1 - 2.3e-06 27.6 0.0 2.4e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3443 PF11925.8 PSC72859.1 - 0.01 14.7 0.1 0.011 14.6 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3443) Acetyltransf_9 PF13527.7 PSC72859.1 - 0.018 15.1 0.0 0.021 14.9 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PSC72859.1 - 0.047 13.8 0.0 0.065 13.4 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase RRM_1 PF00076.22 PSC72860.1 - 5.9e-23 80.5 0.0 9.8e-23 79.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.6 PSC72860.1 - 2.5e-12 47.1 0.3 2.5e-12 47.1 0.3 2.4 3 0 0 3 3 3 1 Hinge domain of cleavage stimulation factor subunit 2 CSTF_C PF14304.6 PSC72860.1 - 5.4e-11 41.9 11.2 2.7e-10 39.7 11.2 2.3 1 0 0 1 1 1 1 Transcription termination and cleavage factor C-terminal partial_CstF PF15861.5 PSC72860.1 - 0.012 15.4 1.4 0.028 14.2 1.4 1.5 1 0 0 1 1 1 0 Partial cleavage stimulation factor domain CbiX PF01903.17 PSC72861.1 - 4.7e-17 62.3 0.0 1.4e-09 38.2 0.0 2.5 2 0 0 2 2 2 2 CbiX MatE PF01554.18 PSC72861.1 - 7.6e-12 45.2 18.4 1e-08 35.0 9.5 3.9 3 1 1 4 4 4 2 MatE Polysacc_synt_C PF14667.6 PSC72861.1 - 5.9e-09 36.1 4.3 5.9e-09 36.1 4.3 3.7 2 2 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain fn3 PF00041.21 PSC72863.1 - 1.9e-86 284.5 0.0 1.2e-09 38.4 0.0 11.1 10 1 0 10 10 10 10 Fibronectin type III domain Pur_ac_phosph_N PF16656.5 PSC72863.1 - 3.6e-29 101.2 0.0 0.0073 16.9 0.0 9.8 10 0 0 10 10 10 7 Purple acid Phosphatase, N-terminal domain SusE PF14292.6 PSC72863.1 - 2.9e-09 37.1 1.1 0.66 10.2 0.0 6.8 8 1 1 9 9 9 3 SusE outer membrane protein PhoD_N PF16655.5 PSC72863.1 - 1.7e-05 25.3 0.5 10 6.7 0.0 6.8 8 1 0 8 8 8 1 PhoD-like phosphatase, N-terminal domain DUF2369 PF10179.9 PSC72863.1 - 0.00053 20.3 0.0 0.77 10.2 0.0 5.1 6 0 0 6 6 6 1 Uncharacterised conserved protein (DUF2369) Interfer-bind PF09294.10 PSC72863.1 - 0.0011 19.3 0.0 21 5.5 0.0 4.6 5 0 0 5 5 5 0 Interferon-alpha/beta receptor, fibronectin type III fn3_4 PF16794.5 PSC72863.1 - 0.028 14.3 0.0 1.4e+02 2.5 0.0 5.5 8 1 0 8 8 8 0 Fibronectin-III type domain CAP PF00188.26 PSC72863.1 - 0.067 14.0 0.1 0.23 12.3 0.1 1.9 1 0 0 1 1 1 0 Cysteine-rich secretory protein family Tissue_fac PF01108.17 PSC72863.1 - 0.21 11.5 1.1 94 2.9 0.0 4.8 6 0 0 6 6 6 0 Tissue factor Pyr_redox_2 PF07992.14 PSC72864.1 - 3.4e-45 154.5 0.0 8.5e-41 140.1 0.0 2.1 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PSC72864.1 - 5.6e-11 42.9 0.1 6.8e-09 36.2 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PSC72864.1 - 0.012 15.2 1.5 0.9 9.1 0.0 3.3 2 1 1 3 3 3 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.12 PSC72864.1 - 0.033 13.3 0.0 13 4.6 0.0 3.1 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 PSC72864.1 - 0.054 13.7 0.0 15 5.9 0.0 2.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 PSC72864.1 - 0.11 12.9 0.0 3.5 8.1 0.0 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding VASt PF16016.5 PSC72865.1 - 3e-34 118.7 0.0 8.8e-34 117.1 0.0 1.8 1 1 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 PSC72865.1 - 3.5e-17 62.3 0.0 6.4e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 GRAM domain NPV_P10 PF05531.12 PSC72865.1 - 0.075 13.5 0.4 0.16 12.4 0.4 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF2570 PF10828.8 PSC72865.1 - 0.92 9.4 3.8 0.98 9.3 0.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) SlyX PF04102.12 PSC72865.1 - 3.1 8.5 7.1 2.6 8.7 1.1 3.3 2 0 0 2 2 2 0 SlyX PHD PF00628.29 PSC72866.1 - 8.9e-08 31.9 6.8 2.2e-07 30.7 6.8 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 PSC72866.1 - 2.2e-06 27.1 1.4 4.4e-06 26.1 1.4 1.5 1 0 0 1 1 1 1 PHD-finger Jas PF16135.5 PSC72866.1 - 0.0088 16.2 2.7 0.032 14.4 2.7 2.0 1 0 0 1 1 1 1 TPL-binding domain in jasmonate signalling Zf_RING PF16744.5 PSC72866.1 - 0.11 12.7 3.7 0.46 10.6 3.7 2.2 1 0 0 1 1 1 0 KIAA1045 RING finger PHD PF00628.29 PSC72867.1 - 8.8e-08 31.9 6.8 2.2e-07 30.7 6.8 1.7 1 0 0 1 1 1 1 PHD-finger PHD_2 PF13831.6 PSC72867.1 - 2.2e-06 27.1 1.4 4.4e-06 26.1 1.4 1.5 1 0 0 1 1 1 1 PHD-finger Jas PF16135.5 PSC72867.1 - 0.0087 16.2 2.7 0.032 14.4 2.7 2.0 1 0 0 1 1 1 1 TPL-binding domain in jasmonate signalling Zf_RING PF16744.5 PSC72867.1 - 0.11 12.7 3.7 0.46 10.6 3.7 2.2 1 0 0 1 1 1 0 KIAA1045 RING finger PI3K_P85_iSH2 PF16454.5 PSC72868.1 - 9.3e-05 22.1 6.3 0.013 15.1 2.5 3.9 4 0 0 4 4 4 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain CCDC158 PF15921.5 PSC72868.1 - 0.0017 16.3 5.7 0.0017 16.3 5.7 2.1 2 1 0 2 2 2 1 Coiled-coil domain-containing protein 158 Csm1_N PF18504.1 PSC72868.1 - 0.01 16.2 30.7 0.39 11.1 1.9 7.3 4 2 3 8 8 8 0 Csm1 N-terminal domain SOGA PF11365.8 PSC72868.1 - 0.01 16.9 27.8 1.1 10.4 4.7 5.6 5 2 1 6 6 6 0 Protein SOGA APG6_N PF17675.1 PSC72868.1 - 0.43 11.1 50.8 3.5 8.2 10.9 6.3 4 2 2 6 6 6 0 Apg6 coiled-coil region zf-C4H2 PF10146.9 PSC72868.1 - 1.7 8.9 14.3 1.7 8.9 3.7 3.3 3 1 0 3 3 3 0 Zinc finger-containing protein Fez1 PF06818.15 PSC72868.1 - 1.8 8.9 37.0 7 7.0 0.8 4.6 3 1 1 4 4 4 0 Fez1 DUF4201 PF13870.6 PSC72868.1 - 3.4 7.4 29.3 0.94 9.2 6.8 5.6 4 2 1 5 5 5 0 Domain of unknown function (DUF4201) MnmE_helical PF12631.7 PSC72869.1 - 3.3e-37 128.7 0.8 8.8e-37 127.3 0.1 2.1 2 0 0 2 2 2 1 MnmE helical domain TrmE_N PF10396.9 PSC72869.1 - 5.7e-37 126.6 0.1 1.4e-36 125.3 0.1 1.8 1 0 0 1 1 1 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 PSC72869.1 - 7.2e-23 80.8 0.0 2.1e-22 79.4 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase KDZ PF18758.1 PSC72869.1 - 2.1e-19 70.0 0.0 4.2e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase FeoB_N PF02421.18 PSC72869.1 - 5e-09 35.9 0.5 3.5e-08 33.1 0.0 2.6 4 0 0 4 4 4 1 Ferrous iron transport protein B GTP_EFTU PF00009.27 PSC72869.1 - 7.7e-05 22.3 0.0 0.056 13.0 0.0 2.5 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PSC72869.1 - 0.00058 19.8 0.0 0.4 10.6 0.1 2.6 2 0 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 PSC72869.1 - 0.002 18.2 0.1 0.14 12.2 0.1 2.6 2 0 0 2 2 2 1 Dynamin family ABC_tran PF00005.27 PSC72869.1 - 0.046 14.2 0.1 0.17 12.4 0.1 1.9 1 0 0 1 1 1 0 ABC transporter AIG1 PF04548.16 PSC72869.1 - 0.084 12.2 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 AIG1 family cobW PF02492.19 PSC72869.1 - 0.086 12.4 0.0 0.51 9.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SUIM_assoc PF16619.5 PSC72869.1 - 0.8 9.8 19.6 0.37 10.9 0.8 4.0 4 0 0 4 4 3 0 Unstructured region C-term to UIM in Ataxin3 BTB PF00651.31 PSC72870.1 - 7.9e-07 29.3 0.0 1.3e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 BTB/POZ domain DEAD PF00270.29 PSC72871.1 - 1.1e-13 51.4 0.0 1.9e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sec63 PF02889.16 PSC72871.1 - 4.9e-09 35.7 0.0 7.3e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain Helicase_C PF00271.31 PSC72871.1 - 2.4e-05 24.6 0.0 8.8e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PSC72872.1 - 1e-13 51.4 0.0 2.1e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Sec63 PF02889.16 PSC72872.1 - 5e-09 35.7 0.0 7.4e-09 35.1 0.0 1.2 1 0 0 1 1 1 1 Sec63 Brl domain Helicase_C PF00271.31 PSC72872.1 - 2.5e-05 24.6 0.0 9e-05 22.8 0.0 2.1 1 1 0 1 1 1 1 Helicase conserved C-terminal domain DUF565 PF04483.12 PSC72873.1 - 5.4e-14 52.5 0.5 8.9e-14 51.8 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF565) DNA_methylase PF00145.17 PSC72874.1 - 1.8e-42 145.9 0.0 2.4e-41 142.2 0.0 2.1 1 1 0 1 1 1 1 C-5 cytosine-specific DNA methylase DUF563 PF04577.14 PSC72874.1 - 1.9e-13 51.0 0.0 4e-13 50.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Elf1 PF05129.13 PSC72874.1 - 0.53 10.4 3.2 1.2 9.2 3.2 1.5 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like Plus-3 PF03126.18 PSC72875.1 - 0.0052 17.3 0.0 0.024 15.2 0.0 1.9 1 1 0 1 1 1 1 Plus-3 domain TRAPPC-Trs85 PF12739.7 PSC72876.1 - 4.5e-68 230.1 0.0 3.3e-66 223.9 0.0 2.1 1 1 0 1 1 1 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TRAPPC9-Trs120 PF08626.11 PSC72876.1 - 9.6e-05 20.0 0.0 0.00014 19.4 0.0 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit WD40 PF00400.32 PSC72877.1 - 1.3e-15 57.5 1.9 7.9e-08 32.9 0.1 4.1 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC72877.1 - 3.5e-08 33.6 0.2 0.0011 19.2 0.0 4.1 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 PSC72877.1 - 0.016 14.8 0.7 0.42 10.2 0.6 2.7 1 1 0 1 1 1 0 PQQ-like domain IKI3 PF04762.12 PSC72877.1 - 0.19 9.7 0.0 2.3 6.1 0.0 2.0 2 0 0 2 2 2 0 IKI3 family CDC45 PF02724.14 PSC72879.1 - 0.45 8.7 2.5 0.63 8.3 2.5 1.1 1 0 0 1 1 1 0 CDC45-like protein TBCC PF07986.12 PSC72880.1 - 3.6e-26 91.3 0.0 6.1e-26 90.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 PSC72880.1 - 0.0024 17.5 0.3 0.0039 16.8 0.3 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TFIIA PF03153.13 PSC72880.1 - 1.3 9.0 16.6 2.5 8.0 16.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Calc_CGRP_IAPP PF00214.19 PSC72880.1 - 9.5 6.6 7.1 10 6.5 0.1 2.7 3 0 0 3 3 3 0 Calcitonin / CGRP / IAPP family Amidohydro_3 PF07969.11 PSC72883.1 - 2.4e-34 119.7 4.7 6.3e-27 95.2 0.1 2.6 3 0 0 3 3 3 2 Amidohydrolase family Amidohydro_1 PF01979.20 PSC72883.1 - 4.9e-09 36.0 0.0 8.4e-09 35.2 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family LRR_4 PF12799.7 PSC72883.1 - 2.7e-06 27.6 0.4 0.0021 18.4 0.0 3.6 2 2 3 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC72883.1 - 2.1e-05 24.2 3.6 0.00046 19.9 0.0 3.9 4 1 0 4 4 4 1 Leucine rich repeat Glyco_trans_2_3 PF13632.6 PSC72883.1 - 0.00034 20.6 0.1 0.00098 19.1 0.1 1.8 2 0 0 2 2 2 1 Glycosyl transferase family group 2 LRR_1 PF00560.33 PSC72883.1 - 0.0016 18.7 0.1 5.6 7.9 0.0 3.5 2 0 0 2 2 2 2 Leucine Rich Repeat LRR_6 PF13516.6 PSC72883.1 - 0.064 13.3 0.3 7.5 6.9 0.0 3.2 3 0 0 3 3 3 0 Leucine Rich repeat AAA PF00004.29 PSC72884.1 - 2.4e-54 183.3 0.0 1.8e-38 132.0 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PSC72884.1 - 2.9e-12 46.2 0.2 7.4e-12 44.9 0.2 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 PSC72884.1 - 2.9e-10 40.8 0.0 0.00078 19.9 0.0 3.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 PSC72884.1 - 1.1e-09 38.6 0.6 0.00063 20.0 0.1 4.2 2 2 1 3 3 3 1 AAA domain AAA_2 PF07724.14 PSC72884.1 - 1e-07 32.3 0.0 0.00025 21.2 0.0 2.9 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 PSC72884.1 - 1.1e-07 31.5 0.0 0.0065 15.7 0.0 2.2 2 0 0 2 2 2 2 TIP49 P-loop domain RuvB_N PF05496.12 PSC72884.1 - 1.3e-07 31.5 0.3 0.028 14.2 0.0 3.2 3 1 1 4 4 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PSC72884.1 - 3.7e-07 30.2 1.4 0.0005 20.1 0.1 3.1 3 1 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 PSC72884.1 - 1.5e-06 28.1 0.1 0.0029 17.4 0.0 2.5 2 0 0 2 2 2 2 AAA domain CDC48_N PF02359.18 PSC72884.1 - 1.8e-06 28.0 0.3 1.8e-05 24.8 0.3 2.6 1 1 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain Sigma54_activat PF00158.26 PSC72884.1 - 3.4e-06 26.9 0.1 0.029 14.1 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain ATPase PF06745.13 PSC72884.1 - 6.1e-06 25.7 0.1 0.0014 18.0 0.0 2.5 2 0 0 2 2 2 1 KaiC PhoH PF02562.16 PSC72884.1 - 9.1e-06 25.3 0.1 0.015 14.7 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein IstB_IS21 PF01695.17 PSC72884.1 - 9.6e-06 25.4 0.1 0.24 11.1 0.0 2.8 3 0 0 3 3 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.21 PSC72884.1 - 2.4e-05 23.8 0.1 0.01 15.2 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 PSC72884.1 - 4.3e-05 23.9 0.0 0.062 13.7 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_30 PF13604.6 PSC72884.1 - 5.9e-05 22.9 0.0 0.27 10.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_7 PF12775.7 PSC72884.1 - 6.4e-05 22.5 0.1 0.036 13.6 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_18 PF13238.6 PSC72884.1 - 7.5e-05 23.3 0.0 0.029 14.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain CDC48_2 PF02933.17 PSC72884.1 - 0.0001 22.0 0.1 0.0017 18.1 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 DUF2075 PF09848.9 PSC72884.1 - 0.0001 21.6 0.1 0.13 11.5 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) AAA_33 PF13671.6 PSC72884.1 - 0.00012 22.2 0.0 0.19 11.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 PSC72884.1 - 0.00017 21.6 0.0 0.32 11.0 0.0 2.3 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 PSC72884.1 - 0.00022 21.3 0.0 0.17 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 PSC72884.1 - 0.00022 21.2 2.7 0.16 11.9 0.0 3.5 4 0 0 4 4 4 1 NACHT domain Parvo_NS1 PF01057.17 PSC72884.1 - 0.00042 19.5 0.0 0.37 9.8 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 PSC72884.1 - 0.0015 18.4 0.0 0.18 11.7 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 PSC72884.1 - 0.0015 17.7 0.0 1.9 7.6 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_11 PF13086.6 PSC72884.1 - 0.0037 17.1 0.1 0.7 9.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.6 PSC72884.1 - 0.0037 17.6 0.2 1.1 9.5 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_28 PF13521.6 PSC72884.1 - 0.0047 17.2 0.0 1.3 9.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 PSC72884.1 - 0.0092 15.9 0.5 19 5.1 0.0 3.8 2 2 2 4 4 4 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 PSC72884.1 - 0.01 16.3 0.0 0.52 10.8 0.0 2.5 2 0 0 2 2 2 0 ABC transporter AAA_25 PF13481.6 PSC72884.1 - 0.016 14.8 4.2 1.9 8.0 0.0 3.3 3 1 0 4 4 3 0 AAA domain ResIII PF04851.15 PSC72884.1 - 0.018 15.1 0.0 8.5 6.3 0.0 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit TniB PF05621.11 PSC72884.1 - 0.022 14.2 0.1 12 5.2 0.0 3.5 2 2 1 3 3 3 0 Bacterial TniB protein Cytidylate_kin PF02224.18 PSC72884.1 - 0.073 12.8 0.1 4.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase T2SSE PF00437.20 PSC72884.1 - 0.1 11.6 0.0 7.7 5.5 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Cupin_4 PF08007.12 PSC72885.1 - 8.8e-49 166.7 0.1 1.2e-48 166.2 0.1 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 PSC72885.1 - 8.5e-07 28.9 0.1 2e-05 24.4 0.1 2.4 1 1 0 1 1 1 1 Cupin-like domain AraC_binding PF02311.19 PSC72885.1 - 0.044 13.7 0.1 0.4 10.6 0.0 2.4 2 0 0 2 2 2 0 AraC-like ligand binding domain BUD22 PF09073.10 PSC72885.1 - 0.047 13.0 6.7 0.087 12.2 6.7 1.4 1 0 0 1 1 1 0 BUD22 Cupin_2 PF07883.11 PSC72885.1 - 0.11 12.2 0.0 0.39 10.4 0.0 1.9 2 0 0 2 2 2 0 Cupin domain Ribosomal_60s PF00428.19 PSC72885.1 - 0.19 12.3 22.1 2.2 8.9 15.1 3.8 3 0 0 3 3 3 0 60s Acidic ribosomal protein Nop14 PF04147.12 PSC72885.1 - 0.95 7.6 9.4 1.3 7.1 9.4 1.1 1 0 0 1 1 1 0 Nop14-like family K_channel_TID PF07941.11 PSC72885.1 - 1.5 9.3 8.2 0.55 10.7 1.3 2.6 2 0 0 2 2 2 0 Potassium channel Kv1.4 tandem inactivation domain DWNN PF08783.11 PSC72886.1 - 1.4e-16 60.5 0.0 2.1e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 PSC72886.1 - 0.00016 21.4 1.4 0.00024 20.8 1.4 1.3 1 0 0 1 1 1 1 Zinc knuckle SNF2_N PF00176.23 PSC72887.1 - 1.7e-95 319.8 0.9 4.4e-95 318.4 0.9 1.7 1 1 0 1 1 1 1 SNF2 family N-terminal domain PHD PF00628.29 PSC72887.1 - 7.9e-07 28.9 4.1 7.9e-07 28.9 4.1 3.3 4 0 0 4 4 4 1 PHD-finger zf-C3HC4_3 PF13920.6 PSC72887.1 - 0.0041 16.9 13.7 0.0041 16.9 13.7 3.3 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) PHD_2 PF13831.6 PSC72887.1 - 0.0054 16.3 0.8 0.0054 16.3 0.8 2.6 3 0 0 3 3 3 1 PHD-finger TPR_1 PF00515.28 PSC72887.1 - 0.029 14.2 0.7 0.1 12.5 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 PSC72887.1 - 0.064 13.4 1.9 0.25 11.5 0.4 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat SecD-TM1 PF13721.6 PSC72887.1 - 0.17 12.4 0.0 0.53 10.8 0.0 1.8 1 0 0 1 1 1 0 SecD export protein N-terminal TM region zf-C3HC4 PF00097.25 PSC72887.1 - 0.31 11.0 13.8 1 9.3 13.8 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_10 PF13374.6 PSC72887.1 - 2.7 8.0 12.6 0.064 13.2 0.4 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat UPF0547 PF10571.9 PSC72887.1 - 6.3 7.0 12.2 7.9 6.7 3.5 2.9 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 ATP_bind_3 PF01171.20 PSC72888.1 - 2.8e-37 128.2 0.0 5e-37 127.4 0.0 1.4 1 0 0 1 1 1 1 PP-loop family Glyco_transf_49 PF13896.6 PSC72888.1 - 1.1e-19 71.1 0.0 5.2e-15 55.6 0.0 3.1 3 1 0 3 3 3 2 Glycosyl-transferase for dystroglycan EF-hand_7 PF13499.6 PSC72888.1 - 5.2e-13 49.2 0.0 1.7e-07 31.6 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PSC72888.1 - 2.4e-09 36.4 0.0 0.00025 20.7 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 PSC72888.1 - 1e-08 34.1 0.1 0.00025 20.3 0.1 3.3 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 PSC72888.1 - 0.00025 20.4 0.2 0.095 12.2 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 PSC72888.1 - 0.049 13.5 2.2 0.36 10.7 0.4 2.6 3 0 0 3 3 3 0 EF-hand domain pair Dockerin_1 PF00404.18 PSC72888.1 - 0.15 12.2 0.0 0.35 11.1 0.0 1.5 1 0 0 1 1 1 0 Dockerin type I domain CitF PF04223.12 PSC72888.1 - 0.19 10.6 0.0 0.38 9.6 0.0 1.4 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) DUF1749 PF08538.10 PSC72892.1 - 3.5e-58 197.1 0.0 4.3e-58 196.8 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) Hydrolase_4 PF12146.8 PSC72892.1 - 4.7e-08 32.6 0.0 1.8e-05 24.1 0.0 2.1 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PSC72892.1 - 1.1e-07 32.7 2.2 1.5e-07 32.3 2.2 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PSC72892.1 - 0.021 14.5 0.0 0.034 13.8 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold DUF4347 PF14252.6 PSC72892.1 - 0.072 12.9 0.2 0.12 12.2 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4347) Ser_hydrolase PF06821.13 PSC72892.1 - 0.088 12.7 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Serine hydrolase DUF900 PF05990.12 PSC72892.1 - 0.16 11.5 0.0 0.23 10.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Psb28 PF03912.14 PSC72893.1 - 1e-41 141.5 0.1 1.7e-41 140.8 0.1 1.3 1 0 0 1 1 1 1 Psb28 protein Lipase_GDSL_2 PF13472.6 PSC72893.1 - 5.6e-06 26.9 0.3 2.2e-05 24.9 0.0 2.2 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Psb28 PF03912.14 PSC72894.1 - 1e-41 141.5 0.1 1.7e-41 140.8 0.1 1.3 1 0 0 1 1 1 1 Psb28 protein Lipase_GDSL_2 PF13472.6 PSC72894.1 - 5.5e-06 26.9 0.3 2.2e-05 24.9 0.0 2.2 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Pollen_allerg_1 PF01357.21 PSC72895.1 - 2.1e-12 46.9 0.0 4e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Pollen allergen Fasciclin PF02469.22 PSC72895.1 - 1.9e-07 31.3 0.0 2.8e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain DPBB_1 PF03330.18 PSC72895.1 - 0.0019 18.5 0.1 0.0039 17.4 0.1 1.5 1 0 0 1 1 1 1 Lytic transglycolase Fer4_21 PF14697.6 PSC72895.1 - 0.16 12.2 4.7 0.29 11.3 4.7 1.3 1 0 0 1 1 1 0 4Fe-4S dicluster domain Ank_4 PF13637.6 PSC72896.1 - 0.034 14.7 0.1 0.096 13.3 0.1 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC72896.1 - 0.04 14.5 0.1 0.13 12.9 0.1 1.9 1 0 0 1 1 1 0 Ankyrin repeat Ank_4 PF13637.6 PSC72897.1 - 0.035 14.7 0.1 0.099 13.3 0.1 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC72897.1 - 0.042 14.4 0.1 0.13 12.9 0.1 1.9 1 0 0 1 1 1 0 Ankyrin repeat TPT PF03151.16 PSC72898.1 - 9.9e-112 373.0 16.0 1.2e-111 372.7 16.0 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PSC72898.1 - 4.3e-12 46.4 22.7 4.5e-07 30.1 11.2 2.3 2 0 0 2 2 2 2 EamA-like transporter family Bromodomain PF00439.25 PSC72898.1 - 0.0018 18.3 0.0 0.0036 17.4 0.0 1.4 1 0 0 1 1 1 1 Bromodomain UAA PF08449.11 PSC72898.1 - 0.03 13.5 10.1 0.046 12.9 9.9 1.4 1 1 0 1 1 1 0 UAA transporter family Hid1 PF12722.7 PSC72898.1 - 7 4.6 6.2 12 3.9 6.2 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Presenilin PF01080.17 PSC72898.1 - 10 4.8 9.4 1.4 7.6 5.2 1.8 2 0 0 2 2 2 0 Presenilin SAP PF02037.27 PSC72899.1 - 2.7e-05 23.8 0.3 5e-05 22.9 0.3 1.5 1 0 0 1 1 1 1 SAP domain HTH_40 PF14493.6 PSC72900.1 - 1.6e-10 41.3 0.0 3e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain SSB PF00436.25 PSC72900.1 - 8.3e-09 35.4 0.0 1.3e-08 34.8 0.0 1.3 1 0 0 1 1 1 1 Single-strand binding protein family RHH_4 PF13467.6 PSC72900.1 - 0.023 14.6 0.1 0.057 13.3 0.1 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix domain DUF525 PF04379.14 PSC72902.1 - 1.5e-31 108.4 0.0 2.3e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 ApaG domain UVR PF02151.19 PSC72902.1 - 6.2e-11 41.7 16.1 6.2e-07 29.0 6.0 2.3 2 0 0 2 2 2 2 UvrB/uvrC motif MG2 PF01835.19 PSC72902.1 - 0.1 13.0 0.1 3.7 8.1 0.0 2.6 2 1 0 2 2 2 0 MG2 domain PK PF00224.21 PSC72903.1 - 2.2e-68 230.7 0.1 1.8e-67 227.7 0.1 1.9 2 0 0 2 2 2 1 Pyruvate kinase, barrel domain GATA PF00320.27 PSC72903.1 - 2.5e-24 84.6 15.1 1.3e-12 47.1 3.5 2.6 2 0 0 2 2 2 2 GATA zinc finger PK_C PF02887.16 PSC72903.1 - 3.8e-22 78.7 0.0 8e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 PSC72903.1 - 9.9e-05 21.6 0.5 0.00018 20.7 0.5 1.4 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family Auto_anti-p27 PF06677.12 PSC72903.1 - 0.0032 17.6 7.9 0.34 11.1 0.8 2.4 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DZR PF12773.7 PSC72903.1 - 0.0099 15.9 6.1 0.072 13.1 0.3 2.7 2 1 0 2 2 2 1 Double zinc ribbon TF_Zn_Ribbon PF08271.12 PSC72903.1 - 0.021 14.3 8.6 0.27 10.8 1.0 2.5 2 0 0 2 2 2 0 TFIIB zinc-binding OrfB_Zn_ribbon PF07282.11 PSC72903.1 - 0.12 12.3 7.8 3.5 7.6 1.2 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain ZF-HD_dimer PF04770.12 PSC72903.1 - 0.26 11.7 3.1 15 6.0 1.1 2.6 2 0 0 2 2 2 0 ZF-HD protein dimerisation region Zn-ribbon_8 PF09723.10 PSC72903.1 - 0.31 11.2 5.5 2.7 8.2 0.4 2.8 2 0 0 2 2 2 0 Zinc ribbon domain zinc_ribbon_2 PF13240.6 PSC72903.1 - 0.32 10.8 7.9 0.4 10.5 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain NMD3 PF04981.13 PSC72903.1 - 0.49 9.8 1.0 7.5 5.9 0.1 2.3 2 0 0 2 2 2 0 NMD3 family eIF-5_eIF-2B PF01873.17 PSC72903.1 - 0.5 10.3 6.6 1.6 8.6 0.8 2.3 2 0 0 2 2 2 0 Domain found in IF2B/IF5 Zn_ribbon_SprT PF17283.2 PSC72903.1 - 2 8.4 3.5 31 4.6 0.7 2.8 2 0 0 2 2 2 0 SprT-like zinc ribbon domain zf-ribbon_3 PF13248.6 PSC72903.1 - 2.6 7.6 10.7 2.4 7.7 0.2 4.1 4 0 0 4 4 4 0 zinc-ribbon domain EMC3_TMCO1 PF01956.16 PSC72904.1 - 3.4e-16 59.4 0.0 4.2e-16 59.1 0.0 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like EamA PF00892.20 PSC72905.1 - 1.3e-09 38.3 12.6 1.2e-07 32.0 0.4 2.5 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.15 PSC72905.1 - 8.5e-06 25.2 0.1 1.3e-05 24.5 0.1 1.2 1 0 0 1 1 1 1 Nucleotide-sugar transporter CRT-like PF08627.10 PSC72905.1 - 8.4e-05 21.7 0.3 0.0079 15.2 0.0 2.4 2 1 0 2 2 2 2 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 PSC72905.1 - 0.00079 19.0 2.6 0.74 9.3 2.0 3.0 2 1 0 2 2 2 2 Solute carrier family 35 TMEM234 PF10639.9 PSC72905.1 - 0.018 15.1 0.0 0.044 13.8 0.0 1.7 1 0 0 1 1 1 0 Putative transmembrane family 234 DUF805 PF05656.14 PSC72905.1 - 0.052 14.0 8.2 0.21 12.0 1.7 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF805) Got1 PF04178.12 PSC72906.1 - 2.7e-26 92.2 17.5 4.4e-26 91.5 17.5 1.4 1 0 0 1 1 1 1 Got1/Sft2-like family Barwin PF00967.17 PSC72907.1 - 6e-27 93.8 1.1 1.3e-26 92.7 1.1 1.6 1 0 0 1 1 1 1 Barwin family DUF4778 PF16008.5 PSC72907.1 - 0.11 12.6 5.0 0.11 12.5 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) ESP PF16590.5 PSC72907.1 - 0.11 12.8 0.3 0.11 12.8 0.3 1.7 2 0 0 2 2 2 0 Exocrine gland-secreting peptide BSP_II PF05432.11 PSC72907.1 - 0.37 10.5 16.2 0.51 10.0 16.2 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) TFIIA PF03153.13 PSC72907.1 - 0.5 10.3 23.7 0.62 10.0 23.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rad51 PF08423.11 PSC72908.1 - 2.1e-36 125.5 0.0 2.9e-19 69.4 0.0 3.2 2 1 0 2 2 2 2 Rad51 CBS PF00571.28 PSC72908.1 - 1.1e-19 70.6 0.3 2.1e-09 37.7 0.0 3.8 4 0 0 4 4 4 3 CBS domain ATPase PF06745.13 PSC72908.1 - 7.5e-05 22.2 0.0 0.00017 21.0 0.0 1.6 1 0 0 1 1 1 1 KaiC RecA PF00154.21 PSC72908.1 - 0.00011 21.8 0.2 0.0014 18.2 0.1 2.2 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 PSC72908.1 - 0.00052 19.6 1.3 0.0017 18.0 0.1 2.5 2 1 0 2 2 2 1 AAA domain PAXNEB PF05625.11 PSC72908.1 - 0.0013 18.0 0.0 0.0026 17.0 0.0 1.4 1 0 0 1 1 1 1 PAXNEB protein Pex14_N PF04695.13 PSC72908.1 - 0.013 16.1 12.2 0.026 15.2 12.2 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DnaB_C PF03796.15 PSC72908.1 - 0.087 12.1 0.1 6.2 6.1 0.0 2.2 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain TFIIA PF03153.13 PSC72908.1 - 1.3 8.9 16.9 2 8.3 16.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LRR_6 PF13516.6 PSC72909.1 - 5.8e-18 63.4 18.8 0.0011 18.8 0.0 11.0 12 0 0 12 12 12 5 Leucine Rich repeat LRR_1 PF00560.33 PSC72909.1 - 1.4e-08 34.1 0.0 46 5.1 0.0 8.4 10 0 0 10 10 10 0 Leucine Rich Repeat LRR_4 PF12799.7 PSC72909.1 - 1.2e-06 28.7 4.4 0.11 13.0 0.0 6.7 8 2 1 9 9 9 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC72909.1 - 0.0011 18.7 7.7 17 5.2 0.0 6.7 7 1 0 7 7 7 2 Leucine rich repeat SMP PF04927.12 PSC72910.1 - 7.1e-05 23.2 6.6 7.1e-05 23.2 6.6 3.6 3 0 0 3 3 3 1 Seed maturation protein Ifi-6-16 PF06140.13 PSC72910.1 - 0.00027 20.8 1.1 0.00027 20.8 1.1 2.7 2 1 1 3 3 3 1 Interferon-induced 6-16 family PDZ_6 PF17820.1 PSC72910.1 - 0.067 13.1 0.6 0.17 11.8 0.2 2.0 2 0 0 2 2 2 0 PDZ domain TIC20 PF16166.5 PSC72911.1 - 9e-17 61.4 9.7 1.1e-16 61.2 9.7 1.1 1 0 0 1 1 1 1 Chloroplast import apparatus Tic20-like Pullulanase_N2 PF17967.1 PSC72911.1 - 0.065 14.1 0.1 0.088 13.7 0.1 1.2 1 0 0 1 1 1 0 Pullulanase N2 domain 2-oxoacid_dh PF00198.23 PSC72912.1 - 6.8e-81 271.1 0.0 8.4e-81 270.8 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 PSC72912.1 - 1.2e-13 50.6 5.3 2.2e-13 49.9 5.3 1.4 1 0 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 PSC72912.1 - 0.0014 18.4 8.0 0.042 13.7 0.7 2.5 1 1 1 2 2 2 2 Biotin-lipoyl like HlyD_D23 PF16576.5 PSC72912.1 - 0.068 12.4 0.3 0.11 11.6 0.3 1.3 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion MSA-2c PF12238.8 PSC72912.1 - 0.47 10.4 8.0 0.76 9.7 8.0 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Sulfatase PF00884.23 PSC72913.1 - 7.7e-47 160.2 0.0 1.1e-46 159.7 0.0 1.2 1 0 0 1 1 1 1 Sulfatase Suf PF05843.14 PSC72913.1 - 3e-16 60.3 5.7 2e-10 41.2 0.0 3.7 3 1 1 4 4 4 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 PSC72913.1 - 9.3e-07 29.2 14.2 0.017 15.9 0.1 6.0 3 1 3 6 6 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 PSC72913.1 - 1.7e-06 28.5 0.3 0.081 13.5 0.0 3.5 3 1 0 3 3 3 2 Tetratricopeptide repeat DUF4976 PF16347.5 PSC72913.1 - 0.00013 22.2 1.0 0.00034 20.8 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4976) TPR_15 PF13429.6 PSC72913.1 - 0.0003 20.1 3.2 0.26 10.5 0.2 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.6 PSC72913.1 - 0.0012 19.3 4.3 0.7 10.7 0.0 4.9 6 0 0 6 6 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 PSC72913.1 - 0.0079 16.5 2.2 1.2 9.5 0.0 4.2 3 2 1 4 4 4 1 Tetratricopeptide repeat Imm49 PF15575.6 PSC72913.1 - 0.02 14.7 1.9 4.7 6.9 0.1 2.9 3 0 0 3 3 3 0 Immunity protein 49 NRDE-2 PF08424.10 PSC72913.1 - 0.024 13.8 0.1 2 7.4 0.0 3.1 1 1 1 3 3 3 0 NRDE-2, necessary for RNA interference TPR_4 PF07721.14 PSC72913.1 - 0.03 14.9 5.3 4.3 8.2 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat PknG_TPR PF16918.5 PSC72913.1 - 0.043 12.6 0.0 0.083 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein kinase G tetratricopeptide repeat TPR_10 PF13374.6 PSC72913.1 - 0.044 13.7 0.3 0.94 9.4 0.0 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 PSC72913.1 - 0.05 14.0 0.0 0.92 10.0 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 PSC72913.1 - 0.14 12.4 0.7 7.4 7.0 0.1 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat Phosphodiest PF01663.22 PSC72913.1 - 0.2 11.2 0.6 1.3 8.5 0.6 2.1 1 1 0 1 1 1 0 Type I phosphodiesterase / nucleotide pyrophosphatase PsbQ PF05757.11 PSC72913.1 - 2.1 8.1 4.5 3.7 7.3 4.1 1.6 2 0 0 2 2 2 0 Oxygen evolving enhancer protein 3 (PsbQ) AA_kinase PF00696.28 PSC72914.1 - 4.5e-39 134.5 0.1 8.5e-39 133.6 0.1 1.5 1 0 0 1 1 1 1 Amino acid kinase family PUA PF01472.20 PSC72914.1 - 2.8e-13 49.6 0.0 6.4e-13 48.5 0.0 1.6 1 0 0 1 1 1 1 PUA domain Spt20 PF12090.8 PSC72914.1 - 0.069 12.8 7.6 0.1 12.2 7.6 1.2 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 PSC72914.1 - 0.07 13.2 9.0 0.21 11.7 9.0 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 PUA_3 PF17785.1 PSC72914.1 - 0.076 12.8 0.0 0.18 11.6 0.0 1.7 1 0 0 1 1 1 0 PUA-like domain TFIIA PF03153.13 PSC72914.1 - 0.47 10.4 15.4 0.66 9.9 15.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MTBP_C PF14920.6 PSC72914.1 - 0.64 9.7 6.5 1.1 8.9 6.5 1.3 1 0 0 1 1 1 0 MDM2-binding DEAD PF00270.29 PSC72915.1 - 4e-19 69.1 0.1 6e-19 68.5 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase rve PF00665.26 PSC72915.1 - 8e-19 68.0 0.0 2.1e-18 66.6 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC72915.1 - 0.0055 16.5 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain CHCH PF06747.13 PSC72916.1 - 0.002 18.2 0.8 0.0044 17.1 0.8 1.6 1 1 0 1 1 1 1 CHCH domain GCK PF07802.11 PSC72916.1 - 0.0067 16.8 1.5 0.0083 16.5 0.8 1.5 1 1 0 1 1 1 1 GCK domain DUF3067 PF11267.8 PSC72917.1 - 2e-28 98.8 0.0 5e-28 97.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3067) HTH_33 PF13592.6 PSC72917.1 - 0.1 12.2 0.0 0.24 11.1 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn helix CYSTM PF12734.7 PSC72918.1 - 5.1e-09 36.3 12.8 5.1e-09 36.3 12.8 5.1 3 1 1 4 4 4 1 Cysteine-rich TM module stress tolerance DHC_N1 PF08385.12 PSC72919.1 - 1.5e-103 347.4 0.0 4.6e-103 345.8 0.0 1.7 2 0 0 2 2 2 1 Dynein heavy chain, N-terminal region 1 DUF1451 PF07295.11 PSC72919.1 - 0.024 14.7 0.6 2.2 8.3 0.0 2.9 2 0 0 2 2 2 0 Zinc-ribbon containing domain DUF1949 PF09186.11 PSC72919.1 - 0.071 13.0 0.2 0.37 10.7 0.2 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1949) HlyD_D4 PF16572.5 PSC72919.1 - 0.62 10.0 3.3 8.2 6.4 0.2 3.7 4 0 0 4 4 4 0 Long alpha hairpin domain of cation efflux system protein, CusB NAD_binding_8 PF13450.6 PSC72920.1 - 9e-14 51.5 0.3 9e-14 51.5 0.3 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 PSC72920.1 - 4.3e-08 32.9 1.2 3.9e-06 26.4 0.1 2.7 2 1 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_2 PF00890.24 PSC72920.1 - 1.6e-05 24.2 0.5 3.5e-05 23.1 0.5 1.6 1 0 0 1 1 1 1 FAD binding domain FAD_binding_3 PF01494.19 PSC72920.1 - 0.00044 19.6 1.3 0.0037 16.6 1.4 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 PSC72920.1 - 0.00094 18.5 0.1 0.0015 17.8 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PSC72920.1 - 0.0026 16.5 0.2 0.0039 16.0 0.2 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 PSC72920.1 - 0.015 15.3 0.4 0.081 12.9 0.3 2.0 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 PSC72920.1 - 0.023 15.2 0.7 0.045 14.3 0.7 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PSC72920.1 - 0.029 13.7 1.5 0.045 13.1 1.5 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Thi4 PF01946.17 PSC72920.1 - 0.034 13.4 0.2 0.058 12.6 0.2 1.3 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 PSC72920.1 - 0.038 13.1 1.1 0.058 12.5 1.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 PSC72920.1 - 0.33 10.2 0.3 0.45 9.7 0.3 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Roughex PF06020.11 PSC72920.1 - 3.7 6.6 5.0 5.2 6.1 5.0 1.1 1 0 0 1 1 1 0 Drosophila roughex protein PAP_fibrillin PF04755.12 PSC72922.1 - 8.6e-42 143.3 0.0 1.3e-14 54.7 0.0 4.2 3 1 0 3 3 3 3 PAP_fibrillin Exostosin PF03016.15 PSC72923.1 - 7.7e-49 166.5 0.0 1e-48 166.1 0.0 1.2 1 0 0 1 1 1 1 Exostosin family EGF_2 PF07974.13 PSC72923.1 - 0.0018 18.6 13.8 0.0018 18.6 13.8 3.3 3 0 0 3 3 3 1 EGF-like domain I-EGF_1 PF18372.1 PSC72923.1 - 2.5 8.3 9.1 6.3 7.0 9.1 1.7 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 TENA_THI-4 PF03070.16 PSC72924.1 - 1.3e-26 93.7 0.0 2.1e-26 93.1 0.0 1.2 1 0 0 1 1 1 1 TENA/THI-4/PQQC family 2OG-FeII_Oxy_3 PF13640.6 PSC72924.1 - 1.3e-11 45.2 0.0 3.9e-11 43.7 0.0 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 PSC72924.1 - 0.035 14.6 0.0 0.076 13.5 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily ubiquitin PF00240.23 PSC72925.1 - 1.3e-11 44.0 0.1 1.6e-11 43.8 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PSC72925.1 - 5.2e-08 32.6 0.1 6.6e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Flg_hook PF02120.16 PSC72925.1 - 0.019 14.8 0.1 0.21 11.5 0.1 2.0 2 0 0 2 2 2 0 Flagellar hook-length control protein FliK TmoB PF06234.12 PSC72925.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.6 1 1 0 1 1 1 0 Toluene-4-monooxygenase system protein B (TmoB) UN_NPL4 PF11543.8 PSC72925.1 - 0.18 12.3 0.0 0.22 12.0 0.0 1.2 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Sua5_yciO_yrdC PF01300.18 PSC72926.1 - 1e-31 109.8 0.0 2.1e-31 108.8 0.0 1.5 1 0 0 1 1 1 1 Telomere recombination RRM_1 PF00076.22 PSC72926.1 - 2.5e-09 36.8 0.0 3.6e-06 26.7 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vir_act_alpha_C PF10400.9 PSC72926.1 - 0.038 14.7 1.8 0.82 10.4 0.8 3.3 4 0 0 4 4 4 0 Virulence activator alpha C-term Apolipoprotein PF01442.18 PSC72926.1 - 0.066 13.1 10.8 0.048 13.5 8.9 1.7 2 0 0 2 2 2 0 Apolipoprotein A1/A4/E domain TetR_C_24 PF17932.1 PSC72926.1 - 0.29 11.4 2.1 0.68 10.2 2.1 1.6 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain REF PF05755.12 PSC72926.1 - 5 6.9 9.5 25 4.6 9.5 2.0 1 1 0 1 1 1 0 Rubber elongation factor protein (REF) adh_short PF00106.25 PSC72928.1 - 3.5e-28 98.4 0.0 3.8e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC72928.1 - 1.9e-21 76.7 0.0 2.5e-21 76.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC72928.1 - 1.2e-09 38.3 0.2 1.6e-09 37.9 0.2 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PSC72928.1 - 6.9e-07 29.3 0.7 1.1e-06 28.6 0.7 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 PSC72928.1 - 0.00015 21.3 0.0 0.00021 20.8 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 PSC72928.1 - 0.013 14.7 0.1 0.023 13.8 0.1 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 PSC72928.1 - 0.072 12.5 0.0 0.095 12.1 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 PSC72929.1 - 2e-16 60.0 0.2 3.8e-11 42.8 0.1 2.0 1 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PSC72929.1 - 2.5e-12 46.9 0.2 4.8e-07 29.6 0.1 2.0 1 1 1 2 2 2 2 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.6 PSC72929.1 - 1.4e-07 31.6 0.5 1.7e-07 31.4 0.5 1.2 1 0 0 1 1 1 1 NAD(P)H-binding KR PF08659.10 PSC72929.1 - 2.8e-07 30.6 0.1 3.9e-07 30.1 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PSC72929.1 - 0.00032 20.3 0.1 0.00049 19.6 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 PSC72929.1 - 0.013 14.6 0.2 0.021 14.0 0.2 1.5 1 1 0 1 1 1 0 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 PSC72929.1 - 0.031 13.7 0.0 0.04 13.3 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase eIF-4B PF06273.11 PSC72930.1 - 1.7e-05 24.1 0.8 1.7e-05 24.1 0.8 5.0 1 1 3 4 4 4 1 Plant specific eukaryotic initiation factor 4B Phage_connect_1 PF05135.13 PSC72930.1 - 0.043 14.3 0.1 0.076 13.5 0.1 1.4 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein HHH_9 PF17674.1 PSC72930.1 - 1.8 9.5 4.5 1.4 9.9 2.4 1.9 1 1 1 2 2 2 0 HHH domain eIF-4B PF06273.11 PSC72931.1 - 1.6e-05 24.2 0.7 1.6e-05 24.2 0.7 5.0 1 1 4 5 5 5 1 Plant specific eukaryotic initiation factor 4B Phage_connect_1 PF05135.13 PSC72931.1 - 0.043 14.3 0.1 0.075 13.5 0.1 1.4 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein HHH_9 PF17674.1 PSC72931.1 - 1.8 9.5 4.4 1.4 9.9 2.3 1.9 1 1 1 2 2 2 0 HHH domain AhpC-TSA_2 PF13911.6 PSC72932.1 - 0.00064 19.8 0.0 0.00083 19.5 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme URO-D PF01208.17 PSC72936.1 - 3.7e-107 358.5 0.0 4.5e-107 358.2 0.0 1.1 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) AAA_12 PF13087.6 PSC72936.1 - 0.035 13.7 0.1 0.06 13.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain Bacillus_HBL PF05791.11 PSC72936.1 - 0.065 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) ADIP PF11559.8 PSC72936.1 - 0.072 13.2 0.9 0.096 12.8 0.0 1.6 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 PSC72936.1 - 0.13 11.6 10.8 0.2 11.0 10.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PHM7_cyt PF14703.6 PSC72936.1 - 0.24 11.6 0.5 0.41 10.8 0.5 1.3 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DivIC PF04977.15 PSC72936.1 - 7 6.5 11.2 1.8 8.4 0.2 3.0 2 1 1 3 3 3 0 Septum formation initiator GCIP PF13324.6 PSC72937.1 - 1.9e-32 112.9 0.0 3.6e-32 112.0 0.0 1.4 2 0 0 2 2 2 1 Grap2 and cyclin-D-interacting MTCP1 PF08991.10 PSC72937.1 - 0.0041 17.3 0.5 0.0041 17.3 0.5 1.9 2 0 0 2 2 2 1 Mature-T-Cell Proliferation I type CHCH PF06747.13 PSC72937.1 - 0.015 15.4 1.2 0.031 14.4 1.2 1.5 1 0 0 1 1 1 0 CHCH domain Phage_TAC_7 PF10109.9 PSC72937.1 - 0.04 14.0 0.1 0.6 10.3 0.0 2.7 2 0 0 2 2 2 0 Phage tail assembly chaperone proteins, E, or 41 or 14 CDK2AP PF09806.9 PSC72937.1 - 4.1 7.4 7.4 0.32 11.0 1.8 2.0 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein TRIC PF05197.13 PSC72938.1 - 4.8e-09 36.1 0.0 6.9e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 TRIC channel Phage_holin_3_3 PF16083.5 PSC72938.1 - 0.001 19.1 0.6 0.004 17.2 0.6 2.0 1 0 0 1 1 1 1 LydA holin phage, holin superfamily III UPF0126 PF03458.13 PSC72938.1 - 0.0039 17.0 2.0 0.0039 17.0 2.0 2.8 3 0 0 3 3 3 1 UPF0126 domain TRIC PF05197.13 PSC72939.1 - 4.8e-09 36.1 0.0 6.9e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 TRIC channel Phage_holin_3_3 PF16083.5 PSC72939.1 - 0.001 19.1 0.6 0.004 17.2 0.6 2.0 1 0 0 1 1 1 1 LydA holin phage, holin superfamily III UPF0126 PF03458.13 PSC72939.1 - 0.0039 17.0 2.0 0.0039 17.0 2.0 2.8 3 0 0 3 3 3 1 UPF0126 domain ParcG PF10274.9 PSC72940.1 - 7.9e-57 192.3 0.0 9.1e-57 192.1 0.0 1.0 1 0 0 1 1 1 1 Parkin co-regulated protein PP2C PF00481.21 PSC72941.1 - 1.8e-28 99.9 0.0 5.3e-28 98.4 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PSC72941.1 - 4.1e-06 26.6 1.9 4.1e-06 26.6 1.9 2.4 3 0 0 3 3 3 1 Protein phosphatase 2C AP3D1 PF06375.11 PSC72941.1 - 0.1 12.8 3.3 0.26 11.5 3.3 1.6 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 RNA_polI_A34 PF08208.11 PSC72941.1 - 5.9 6.9 14.6 2 8.4 11.0 2.1 2 0 0 2 2 2 0 DNA-directed RNA polymerase I subunit RPA34.5 RVT_1 PF00078.27 PSC72942.1 - 9.1e-18 64.6 0.0 1.3e-17 64.1 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) CDP-OH_P_transf PF01066.21 PSC72942.1 - 0.14 13.0 0.0 0.3 11.9 0.0 1.6 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase RecR PF02132.15 PSC72942.1 - 0.3 10.7 3.8 0.78 9.4 3.8 1.7 1 0 0 1 1 1 0 RecR protein Pkinase PF00069.25 PSC72943.1 - 1.9e-58 197.9 0.0 2.9e-58 197.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain EF-hand_7 PF13499.6 PSC72943.1 - 5.7e-24 84.4 4.8 7.8e-12 45.5 0.4 3.2 2 1 1 3 3 3 3 EF-hand domain pair Pkinase_Tyr PF07714.17 PSC72943.1 - 3.5e-21 75.6 0.0 5.2e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_5 PF13202.6 PSC72943.1 - 4.5e-21 73.3 0.9 1.2e-06 27.7 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_1 PF00036.32 PSC72943.1 - 1.3e-20 71.3 0.8 4.9e-07 28.9 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PSC72943.1 - 6.9e-18 63.0 0.5 0.0041 16.9 0.0 4.8 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 PSC72943.1 - 4e-17 61.8 4.4 4.5e-06 26.4 0.4 4.1 3 1 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PSC72943.1 - 2.5e-06 27.8 0.6 0.041 14.2 0.5 2.7 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Kdo PF06293.14 PSC72943.1 - 0.021 14.2 0.0 0.049 13.0 0.0 1.7 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PSC72943.1 - 0.022 14.1 0.3 0.86 8.9 0.2 2.8 2 1 0 2 2 2 0 Kinase-like Dockerin_1 PF00404.18 PSC72943.1 - 0.043 14.0 1.5 3 8.1 0.0 3.5 2 1 1 3 3 3 0 Dockerin type I domain rve PF00665.26 PSC72944.1 - 1.4e-18 67.2 0.0 3.2e-18 66.1 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain PAS_4 PF08448.10 PSC72944.1 - 0.00024 21.3 0.0 0.0012 19.1 0.0 2.2 1 0 0 1 1 1 1 PAS fold rve_3 PF13683.6 PSC72944.1 - 0.012 15.4 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain GAF_2 PF13185.6 PSC72944.1 - 0.014 15.7 2.7 0.023 15.0 0.0 2.9 3 1 1 4 4 4 0 GAF domain IBN_N PF03810.19 PSC72945.1 - 4.3e-11 42.6 0.0 1.9e-10 40.5 0.0 2.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.22 PSC72945.1 - 1.5e-05 24.8 8.2 0.22 11.9 0.0 6.8 7 0 0 7 7 7 2 HEAT repeat Xpo1 PF08389.12 PSC72945.1 - 0.0013 18.8 0.7 0.032 14.3 0.0 3.2 3 1 0 3 3 3 1 Exportin 1-like protein RIH_assoc PF08454.11 PSC72945.1 - 0.059 13.2 0.0 0.43 10.5 0.0 2.5 2 0 0 2 2 2 0 RyR and IP3R Homology associated CLASP_N PF12348.8 PSC72945.1 - 0.1 12.2 0.1 0.98 8.9 0.0 2.5 3 0 0 3 3 3 0 CLASP N terminal Adaptin_N PF01602.20 PSC72945.1 - 0.12 10.9 0.0 4.7 5.6 0.0 2.2 2 0 0 2 2 2 0 Adaptin N terminal region Cnd1 PF12717.7 PSC72945.1 - 0.17 11.9 0.0 0.55 10.3 0.0 1.9 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 HTH_15 PF12324.8 PSC72945.1 - 0.3 11.1 1.9 2.6 8.1 0.1 3.4 2 0 0 2 2 2 0 Helix-turn-helix domain of alkylmercury lyase MFS_1_like PF12832.7 PSC72947.1 - 2.1e-48 165.1 0.2 3.5e-45 154.5 0.0 3.1 2 2 0 2 2 2 1 MFS_1 like family MFS_1 PF07690.16 PSC72947.1 - 1.5e-08 34.0 9.1 1.5e-08 34.0 9.1 4.7 2 1 1 3 3 3 3 Major Facilitator Superfamily Nuc_H_symport PF03825.16 PSC72947.1 - 3.2e-08 33.0 5.6 0.001 18.1 0.3 3.2 2 1 0 2 2 2 2 Nucleoside H+ symporter LacY_symp PF01306.19 PSC72947.1 - 0.00033 19.6 0.4 0.00033 19.6 0.4 1.9 2 0 0 2 2 2 1 LacY proton/sugar symporter Fer2_3 PF13085.6 PSC72948.1 - 1.8e-13 50.5 0.2 4.7e-13 49.1 0.2 1.7 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain zf-MYND PF01753.18 PSC72948.1 - 4.4e-12 45.9 13.5 1.2e-11 44.5 13.5 1.8 1 0 0 1 1 1 1 MYND finger Ank_4 PF13637.6 PSC72948.1 - 2.4e-11 43.9 0.0 3.3e-06 27.5 0.0 3.4 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PSC72948.1 - 1.6e-08 35.0 0.0 4.2e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC72948.1 - 1.1e-06 28.8 2.5 0.00046 20.4 0.0 3.9 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 PSC72948.1 - 1.2e-06 28.7 0.1 0.00043 20.6 0.0 3.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 PSC72948.1 - 4.4e-05 23.5 0.1 0.013 16.0 0.0 3.6 3 0 0 3 3 2 1 Ankyrin repeat Fer2 PF00111.27 PSC72948.1 - 0.012 15.5 4.7 0.012 15.5 4.7 2.5 3 0 0 3 3 3 0 2Fe-2S iron-sulfur cluster binding domain zf-C6H2 PF15801.5 PSC72948.1 - 0.029 14.7 5.6 0.09 13.1 5.6 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding DUF3515 PF12028.8 PSC72948.1 - 0.074 12.8 1.5 0.18 11.5 1.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3515) TPR_8 PF13181.6 PSC72948.1 - 0.16 12.2 1.2 11 6.6 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 PSC72948.1 - 0.36 11.2 16.0 2.3 8.6 5.7 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat PolC_DP2 PF03833.13 PSC72948.1 - 1 7.1 2.9 1.6 6.5 2.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 TPR_1 PF00515.28 PSC72948.1 - 1.9 8.4 5.3 8.2 6.4 1.7 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Tweety PF04906.13 PSC72949.1 - 0.17 10.5 1.4 0.26 9.9 1.4 1.1 1 0 0 1 1 1 0 Tweety SecG PF03840.14 PSC72949.1 - 0.8 9.8 0.1 0.8 9.8 0.1 3.1 3 1 0 3 3 3 0 Preprotein translocase SecG subunit Tcp11 PF05794.13 PSC72950.1 - 5.3e-25 88.4 0.0 6.6e-20 71.6 0.0 2.1 2 0 0 2 2 2 2 T-complex protein 11 Aa_trans PF01490.18 PSC72952.1 - 9.6e-55 185.9 7.2 1.8e-31 109.2 3.0 2.0 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein COX14 PF14880.6 PSC72952.1 - 0.38 10.6 0.0 0.38 10.6 0.0 3.0 3 0 0 3 3 3 0 Cytochrome oxidase c assembly RVT_1 PF00078.27 PSC72954.1 - 1e-05 25.1 0.0 0.064 12.8 0.0 2.3 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) AvrPtoB_bdg PF16847.5 PSC72954.1 - 0.18 12.3 1.3 0.91 10.0 0.1 2.6 2 1 1 3 3 3 0 Avirulence AvrPtoB, BAK1-binding domain tRNA-synt_2b PF00587.25 PSC72955.1 - 8.9e-37 126.8 0.0 1.3e-36 126.2 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 PSC72955.1 - 4.9e-26 91.1 4.0 8.8e-26 90.3 4.0 1.4 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain Cep57_CLD_2 PF14197.6 PSC72955.1 - 0.0012 18.9 0.3 0.0028 17.7 0.3 1.6 1 0 0 1 1 1 1 Centrosome localisation domain of PPC89 Phage_GP20 PF06810.11 PSC72955.1 - 0.0074 16.1 4.5 0.015 15.1 4.5 1.4 1 0 0 1 1 1 1 Phage minor structural protein GP20 CEP209_CC5 PF16574.5 PSC72955.1 - 0.05 13.8 3.1 0.11 12.7 2.2 1.9 2 0 0 2 2 2 0 Coiled-coil region of centrosome protein CE290 Vps52 PF04129.12 PSC72955.1 - 0.09 11.5 0.2 0.12 11.1 0.2 1.1 1 0 0 1 1 1 0 Vps52 / Sac2 family DUF4315 PF14193.6 PSC72955.1 - 0.21 11.6 6.7 0.45 10.6 6.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4315) DUF1365 PF07103.11 PSC72956.1 - 2.7e-43 148.4 0.0 1.2e-41 142.9 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF1365) Nitroreductase PF00881.24 PSC72957.1 - 6.8e-19 68.5 0.0 8.4e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family Nitroreductase PF00881.24 PSC72958.1 - 2.3e-18 66.8 0.0 3.1e-18 66.4 0.0 1.1 1 0 0 1 1 1 1 Nitroreductase family ATP-sulfurylase PF01747.17 PSC72959.1 - 1.3e-67 227.4 0.0 2.1e-67 226.7 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 PSC72959.1 - 2.5e-44 150.7 0.0 3.7e-43 147.0 0.0 2.1 2 0 0 2 2 2 1 PUA-like domain ATP-sulfurylase PF01747.17 PSC72960.1 - 1.3e-67 227.4 0.0 2.1e-67 226.7 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase PUA_2 PF14306.6 PSC72960.1 - 2.5e-44 150.8 0.0 3.7e-43 147.0 0.0 2.1 2 0 0 2 2 2 1 PUA-like domain DUF1499 PF07386.11 PSC72961.1 - 8.8e-05 23.0 0.1 0.35 11.4 0.0 2.8 3 0 0 3 3 3 2 Protein of unknown function (DUF1499) PsbQ PF05757.11 PSC72961.1 - 0.099 12.4 2.4 0.2 11.4 2.4 1.5 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Mpv17_PMP22 PF04117.12 PSC72962.1 - 7.4e-20 70.9 0.7 7.4e-20 70.9 0.7 1.5 2 0 0 2 2 2 1 Mpv17 / PMP22 family PetG PF02529.15 PSC72962.1 - 0.19 11.6 2.9 0.82 9.6 0.0 2.5 2 0 0 2 2 2 0 Cytochrome B6-F complex subunit 5 GNAT_acetyltr_2 PF13718.6 PSC72964.1 - 1.8e-90 302.3 0.0 2.6e-90 301.8 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 PSC72964.1 - 1.1e-61 207.8 0.0 6.4e-61 205.3 0.0 2.1 2 0 0 2 2 2 1 Helicase tRNA_bind_2 PF13725.6 PSC72964.1 - 1.3e-56 191.9 0.0 2e-56 191.4 0.0 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain DUF1726 PF08351.11 PSC72964.1 - 3e-31 107.2 0.1 6.1e-31 106.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) EamA PF00892.20 PSC72964.1 - 4.4e-06 26.9 28.3 0.00032 20.9 5.7 3.4 3 0 0 3 3 3 3 EamA-like transporter family AAA_22 PF13401.6 PSC72964.1 - 0.00048 20.4 0.6 0.012 15.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PSC72964.1 - 0.0095 15.7 0.9 0.084 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain GNAT_acetyltr_2 PF13718.6 PSC72965.1 - 1.8e-90 302.3 0.0 2.6e-90 301.8 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.14 PSC72965.1 - 1.1e-61 207.8 0.0 6.4e-61 205.3 0.0 2.1 2 0 0 2 2 2 1 Helicase tRNA_bind_2 PF13725.6 PSC72965.1 - 1.3e-56 191.9 0.0 2e-56 191.4 0.0 1.3 1 0 0 1 1 1 1 Possible tRNA binding domain DUF1726 PF08351.11 PSC72965.1 - 3e-31 107.2 0.1 6.1e-31 106.2 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1726) EamA PF00892.20 PSC72965.1 - 4.4e-06 26.9 28.3 0.00032 20.9 5.7 3.4 3 0 0 3 3 3 3 EamA-like transporter family AAA_22 PF13401.6 PSC72965.1 - 0.00048 20.4 0.6 0.012 15.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 PSC72965.1 - 0.0095 15.7 0.9 0.084 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain Ank_2 PF12796.7 PSC72966.1 - 0.013 16.1 0.5 19 5.9 0.0 3.6 2 2 1 3 3 3 0 Ankyrin repeats (3 copies) PAP1 PF08601.10 PSC72966.1 - 0.56 9.9 2.3 0.87 9.2 2.3 1.2 1 0 0 1 1 1 0 Transcription factor PAP1 Ank_5 PF13857.6 PSC72966.1 - 0.75 10.2 3.4 42 4.6 0.1 3.5 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Acetate_kinase PF00871.17 PSC72967.1 - 6.7e-102 341.1 0.0 8.3e-102 340.8 0.0 1.0 1 0 0 1 1 1 1 Acetokinase family DNA_repr_REX1B PF14966.6 PSC72968.1 - 1.3e-25 89.9 1.9 7.6e-25 87.4 0.4 2.2 2 0 0 2 2 2 1 DNA repair REX1-B Tfb5 PF06331.12 PSC72968.1 - 8.9e-11 41.6 0.0 2.1e-10 40.4 0.0 1.6 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 Phycobilisome PF00502.19 PSC72968.1 - 0.059 13.3 0.1 0.059 13.3 0.1 2.1 3 0 0 3 3 3 0 Phycobilisome protein TAFII28 PF04719.14 PSC72969.1 - 1.2e-20 73.4 0.0 5.8e-20 71.2 0.0 2.0 1 1 1 2 2 2 1 hTAFII28-like protein conserved region NPL4 PF05021.15 PSC72970.1 - 1.9e-22 80.0 0.0 1.4e-11 44.3 0.0 3.2 2 1 0 2 2 2 2 NPL4 family UN_NPL4 PF11543.8 PSC72970.1 - 3e-10 40.4 0.0 1.1e-08 35.4 0.0 3.1 2 1 0 2 2 2 1 Nuclear pore localisation protein NPL4 Lebercilin PF15619.6 PSC72971.1 - 0.0042 16.8 13.0 0.008 15.9 13.0 1.4 1 1 0 1 1 1 1 Ciliary protein causing Leber congenital amaurosis disease DUF4200 PF13863.6 PSC72971.1 - 0.011 16.1 10.4 0.016 15.6 10.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) HMMR_N PF15905.5 PSC72971.1 - 0.025 14.1 8.5 0.034 13.6 8.5 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal BicD PF09730.9 PSC72971.1 - 0.034 12.6 7.7 0.042 12.3 7.7 1.1 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D Golgin_A5 PF09787.9 PSC72971.1 - 0.037 13.5 14.9 0.046 13.2 14.9 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 5 Spc7 PF08317.11 PSC72971.1 - 0.084 11.7 11.6 0.11 11.4 11.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Tweety PF04906.13 PSC72971.1 - 0.1 11.2 2.5 0.13 10.9 2.5 1.1 1 0 0 1 1 1 0 Tweety DUF3450 PF11932.8 PSC72971.1 - 0.12 11.7 14.5 0.21 10.8 14.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) SPICE PF15678.5 PSC72971.1 - 0.13 11.5 9.6 0.23 10.8 9.6 1.4 1 0 0 1 1 1 0 Centriole duplication and mitotic chromosome congression Troponin PF00992.20 PSC72971.1 - 0.23 11.8 8.0 0.35 11.2 8.0 1.3 1 0 0 1 1 1 0 Troponin ERM PF00769.19 PSC72971.1 - 0.32 10.8 13.9 0.51 10.1 13.9 1.4 1 0 0 1 1 1 0 Ezrin/radixin/moesin family HAP1_N PF04849.13 PSC72971.1 - 0.34 10.1 11.9 0.44 9.7 11.9 1.2 1 0 0 1 1 1 0 HAP1 N-terminal conserved region IFT57 PF10498.9 PSC72971.1 - 0.41 9.6 7.8 0.52 9.2 7.8 1.1 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 V_ATPase_I PF01496.19 PSC72971.1 - 0.53 8.1 1.8 0.64 7.9 1.8 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family MnmE_helical PF12631.7 PSC72971.1 - 0.53 10.4 5.7 0.89 9.7 5.7 1.3 1 0 0 1 1 1 0 MnmE helical domain SlyX PF04102.12 PSC72971.1 - 0.59 10.8 21.5 5.7 7.6 0.5 3.4 1 1 2 3 3 3 0 SlyX FH2 PF02181.23 PSC72971.1 - 0.67 9.0 4.5 0.89 8.6 4.5 1.1 1 0 0 1 1 1 0 Formin Homology 2 Domain DUF1664 PF07889.12 PSC72971.1 - 0.71 9.9 4.2 1.4 8.9 4.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FapA PF03961.13 PSC72971.1 - 0.72 8.4 3.0 0.9 8.1 3.0 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 PSC72971.1 - 0.95 8.6 6.5 1.2 8.3 6.5 1.1 1 0 0 1 1 1 0 TMPIT-like protein Jnk-SapK_ap_N PF09744.9 PSC72971.1 - 1.2 9.3 13.9 1.8 8.7 13.9 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 CENP-H PF05837.12 PSC72971.1 - 2.2 8.7 10.6 4 7.9 10.6 1.5 1 0 0 1 1 1 0 Centromere protein H (CENP-H) Pinin_SDK_memA PF04696.13 PSC72971.1 - 2.6 8.1 15.2 4 7.5 15.2 1.2 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region DUF4061 PF13270.6 PSC72971.1 - 2.7 8.4 8.3 4.6 7.6 8.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4061) FAP206 PF12018.8 PSC72971.1 - 2.8 7.4 7.7 3.6 7.0 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function TraT PF05818.12 PSC72971.1 - 3 7.5 6.2 0.13 12.0 0.4 1.6 2 0 0 2 2 2 0 Enterobacterial TraT complement resistance protein DUF4407 PF14362.6 PSC72971.1 - 3 7.1 10.7 3.6 6.8 10.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) GBP_C PF02841.14 PSC72971.1 - 3.3 7.0 13.0 4.2 6.7 13.0 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain Filament PF00038.21 PSC72971.1 - 4.3 6.8 15.0 15 5.0 14.5 1.6 1 1 0 1 1 1 0 Intermediate filament protein ADIP PF11559.8 PSC72971.1 - 4.6 7.3 16.6 6.4 6.8 16.6 1.2 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding ATG16 PF08614.11 PSC72971.1 - 4.7 7.4 19.3 0.98 9.6 15.3 1.9 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) MCU PF04678.13 PSC72971.1 - 5.6 7.0 7.1 8.9 6.4 7.1 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter Spc24 PF08286.11 PSC72971.1 - 10 6.5 6.7 20 5.5 6.7 1.6 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 CKS PF01111.19 PSC72972.1 - 8e-35 118.9 0.9 9.7e-35 118.7 0.9 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit Methuselah_N PF06652.12 PSC72972.1 - 0.17 11.8 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Methuselah N-terminus 2OG-FeII_Oxy_3 PF13640.6 PSC72973.1 - 3.5e-17 63.1 0.0 5.7e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 PSC72973.1 - 5.3e-06 26.9 0.0 1.5e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 PSC72973.1 - 0.00022 21.7 6.6 0.00084 19.8 6.6 2.1 1 1 0 1 1 1 1 ShK domain-like GST_N_3 PF13417.6 PSC72974.1 - 4.6e-14 52.6 0.1 1.4e-13 51.0 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PSC72974.1 - 3e-12 46.7 0.0 6.8e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PSC72974.1 - 3.3e-07 30.6 0.0 7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PSC72974.1 - 1e-06 28.6 0.0 3.5e-06 27.0 0.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 PSC72974.1 - 0.00012 22.6 0.0 0.00024 21.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 PSC72974.1 - 0.00083 19.5 0.1 0.0016 18.6 0.1 1.5 1 0 0 1 1 1 1 Glutaredoxin GST_C PF00043.25 PSC72974.1 - 0.0012 19.0 0.0 0.0028 17.9 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 PSC72974.1 - 0.0014 19.3 0.0 0.0044 17.7 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain zf-HIT PF04438.16 PSC72977.1 - 9e-08 31.9 8.0 1.3e-07 31.4 8.0 1.2 1 0 0 1 1 1 1 HIT zinc finger Prok-RING_4 PF14447.6 PSC72977.1 - 0.2 11.6 7.8 0.36 10.7 7.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PolC_DP2 PF03833.13 PSC72977.1 - 2.1 6.1 3.4 3 5.6 3.4 1.2 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF2076 PF09849.9 PSC72978.1 - 8.6 6.3 7.5 0.3 11.1 0.8 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF1826 PF08856.11 PSC72979.1 - 2.7e-39 135.2 0.0 3.4e-39 134.9 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1826) zf-Tim10_DDP PF02953.15 PSC72981.1 - 1.7e-15 56.4 4.6 1.7e-15 56.4 4.6 1.7 2 0 0 2 2 2 1 Tim10/DDP family zinc finger Acetyltransf_10 PF13673.7 PSC72981.1 - 1.1e-11 44.8 0.0 2.6e-11 43.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PSC72981.1 - 1.2e-10 41.7 0.0 2.7e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PSC72981.1 - 5e-09 36.5 0.0 1.4e-08 35.1 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC72981.1 - 4.9e-05 23.2 0.0 0.00024 21.0 0.0 2.1 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.7 PSC72981.1 - 0.00056 20.0 0.0 0.0014 18.7 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SAE2 PF08573.10 PSC72981.1 - 0.17 13.0 0.4 0.36 12.0 0.4 1.5 1 0 0 1 1 1 0 DNA repair protein endonuclease SAE2/CtIP C-terminus LRR_8 PF13855.6 PSC72981.1 - 0.33 10.7 2.7 3.8 7.3 0.1 3.3 2 1 1 3 3 3 0 Leucine rich repeat DPBB_1 PF03330.18 PSC72982.1 - 8.4e-05 22.8 0.1 0.00017 21.8 0.1 1.5 1 0 0 1 1 1 1 Lytic transglycolase Peptidase_C78 PF07910.13 PSC72983.1 - 6.4e-46 156.5 0.0 8.3e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C78 ATC_hydrolase PF14196.6 PSC72984.1 - 4.7e-05 24.2 0.0 4.9e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 L-2-amino-thiazoline-4-carboxylic acid hydrolase Acyl-CoA_dh_1 PF00441.24 PSC72985.1 - 6.5e-47 159.5 1.1 2e-46 157.9 1.1 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 PSC72985.1 - 6e-30 104.2 0.1 1.4e-29 103.0 0.1 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 PSC72985.1 - 4.7e-26 90.8 0.0 8.9e-26 89.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 PSC72985.1 - 1.3e-21 77.3 0.6 1.3e-21 77.3 0.6 2.7 3 0 0 3 3 3 1 Acyl-CoA dehydrogenase, C-terminal domain Fasciclin PF02469.22 PSC72986.1 - 5.8e-14 52.4 0.1 1.1e-13 51.6 0.1 1.4 1 0 0 1 1 1 1 Fasciclin domain RVT_1 PF00078.27 PSC72986.1 - 0.19 11.2 0.0 0.3 10.6 0.0 1.3 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) GLTP PF08718.11 PSC72987.1 - 6.6e-28 97.9 0.0 1.4e-27 96.8 0.0 1.5 2 0 0 2 2 2 1 Glycolipid transfer protein (GLTP) Peptidase_C50 PF03568.17 PSC72988.1 - 2.5e-85 287.0 0.0 5.1e-69 233.3 0.0 2.2 2 0 0 2 2 2 2 Peptidase family C50 2OG-FeII_Oxy_3 PF13640.6 PSC72989.1 - 2.4e-20 73.2 0.0 4.5e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 PSC72989.1 - 1e-09 38.8 0.0 2e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily FPN1 PF06963.12 PSC72990.1 - 9.7e-99 330.9 17.8 1.1e-98 330.6 17.8 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) E1-E2_ATPase PF00122.20 PSC72991.1 - 3.1e-36 124.6 0.1 3.1e-36 124.6 0.1 3.2 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 PSC72991.1 - 5.4e-19 69.3 17.0 5.4e-19 69.3 17.0 3.8 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 PSC72991.1 - 0.011 15.5 1.1 0.022 14.5 1.1 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase VirE PF05272.11 PSC72991.1 - 0.14 11.8 0.0 0.28 10.9 0.0 1.4 1 0 0 1 1 1 0 Virulence-associated protein E Metallophos PF00149.28 PSC72992.1 - 4.6e-10 40.3 0.0 6.5e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase IBN_N PF03810.19 PSC72993.1 - 1.5e-13 50.4 0.0 2.6e-11 43.3 0.0 3.0 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 PSC72993.1 - 4.5e-08 32.3 0.0 2.3e-05 23.4 0.0 2.3 2 0 0 2 2 2 2 Cse1 HEAT_2 PF13646.6 PSC72993.1 - 4.4e-05 23.8 5.8 0.00069 20.0 0.6 4.3 3 1 0 3 3 3 1 HEAT repeats Xpo1 PF08389.12 PSC72993.1 - 8.4e-05 22.7 1.1 0.00067 19.7 0.0 2.8 3 0 0 3 3 3 1 Exportin 1-like protein HEAT PF02985.22 PSC72993.1 - 0.0022 18.1 3.2 5.3 7.6 0.1 5.1 4 0 0 4 4 4 2 HEAT repeat SDA1 PF05285.12 PSC72993.1 - 0.04 13.3 6.4 0.063 12.7 6.4 1.2 1 0 0 1 1 1 0 SDA1 HEAT_EZ PF13513.6 PSC72993.1 - 0.7 10.5 0.0 0.7 10.5 0.0 6.8 8 2 1 9 9 9 0 HEAT-like repeat BUD22 PF09073.10 PSC72993.1 - 1.4 8.2 13.5 2.2 7.5 13.5 1.2 1 0 0 1 1 1 0 BUD22 DNA_ligase_A_M PF01068.21 PSC72994.1 - 3.1e-59 200.1 0.0 4.9e-59 199.4 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 PSC72994.1 - 2.9e-45 154.7 0.0 6.7e-45 153.5 0.0 1.7 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 PSC72994.1 - 3.2e-21 75.8 0.0 7.8e-21 74.5 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 PSC72994.1 - 5.2e-06 26.9 0.0 8.7e-06 26.1 0.0 1.4 1 0 0 1 1 1 1 RNA ligase mRNA_cap_enzyme PF01331.19 PSC72994.1 - 0.088 12.6 0.0 0.74 9.6 0.0 2.1 1 1 0 1 1 1 0 mRNA capping enzyme, catalytic domain Pkinase PF00069.25 PSC72995.1 - 4.8e-37 127.7 0.0 9.4e-36 123.5 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC72995.1 - 1.6e-15 57.1 0.0 4.2e-15 55.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase BTB PF00651.31 PSC72995.1 - 5.7e-10 39.4 0.0 3.7e-08 33.6 0.0 2.4 2 0 0 2 2 2 1 BTB/POZ domain Kinase-like PF14531.6 PSC72995.1 - 5.5e-06 25.9 0.0 1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PSC72995.1 - 0.00016 21.1 0.1 0.00036 20.0 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Rho_Binding PF08912.11 PSC72995.1 - 3.4 8.6 5.1 8.6 7.3 5.1 1.7 1 0 0 1 1 1 0 Rho Binding Mo25 PF08569.11 PSC72997.1 - 1.8e-117 392.4 3.6 2.2e-117 392.1 3.6 1.0 1 0 0 1 1 1 1 Mo25-like XPC-binding PF09280.11 PSC72997.1 - 0.071 12.9 0.3 0.29 10.9 0.3 2.1 1 0 0 1 1 1 0 XPC-binding domain KOW PF00467.29 PSC72998.1 - 0.065 13.2 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 KOW motif NusG PF02357.19 PSC72998.1 - 0.11 13.0 0.1 0.2 12.2 0.1 1.3 1 0 0 1 1 1 0 Transcription termination factor nusG E1-E2_ATPase PF00122.20 PSC72999.1 - 1.2e-43 148.8 0.5 3.9e-43 147.1 0.3 2.1 2 0 0 2 2 2 1 E1-E2 ATPase RecX PF02631.16 PSC72999.1 - 2.5e-22 79.6 4.5 2.8e-22 79.4 2.4 2.3 1 1 1 2 2 2 1 RecX family Hydrolase PF00702.26 PSC72999.1 - 3.7e-17 63.3 0.1 2.1e-16 60.9 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PSC72999.1 - 7.7e-12 44.7 0.0 2.7e-11 43.0 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Ysc84 PF04366.12 PSC72999.1 - 1.3e-08 34.6 0.0 3.3e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Las17-binding protein actin regulator Hydrolase_3 PF08282.12 PSC72999.1 - 0.0006 19.6 0.8 0.0036 17.1 0.8 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CPP1-like PF11833.8 PSC72999.1 - 0.0068 16.1 1.6 0.024 14.3 1.6 1.9 1 0 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF3377 PF11857.8 PSC72999.1 - 0.027 14.4 0.1 4.4 7.3 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) Pex14_N PF04695.13 PSC72999.1 - 0.033 14.9 6.3 1.4 9.5 0.2 2.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Bap31_Bap29_C PF18035.1 PSC72999.1 - 0.06 13.4 0.6 0.23 11.5 0.6 2.1 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain BLOC1_2 PF10046.9 PSC72999.1 - 1.9 8.8 6.6 0.49 10.7 0.2 3.3 4 0 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliD_N PF02465.18 PSC72999.1 - 5 7.9 12.6 1.9 9.2 5.7 3.6 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus E1-E2_ATPase PF00122.20 PSC73000.1 - 1.2e-43 148.8 0.5 3.9e-43 147.1 0.3 2.1 2 0 0 2 2 2 1 E1-E2 ATPase RecX PF02631.16 PSC73000.1 - 2e-22 79.9 4.3 2.5e-22 79.6 2.4 2.3 1 1 0 1 1 1 1 RecX family Hydrolase PF00702.26 PSC73000.1 - 3.6e-17 63.3 0.1 2.1e-16 60.9 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PSC73000.1 - 7.7e-12 44.7 0.0 2.7e-11 43.0 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Ysc84 PF04366.12 PSC73000.1 - 1.3e-08 34.6 0.0 3.3e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Las17-binding protein actin regulator Hydrolase_3 PF08282.12 PSC73000.1 - 0.0006 19.6 0.8 0.0036 17.1 0.8 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CPP1-like PF11833.8 PSC73000.1 - 0.0068 16.1 1.6 0.024 14.3 1.6 1.9 1 0 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF3377 PF11857.8 PSC73000.1 - 0.027 14.4 0.1 4.3 7.3 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) Pex14_N PF04695.13 PSC73000.1 - 0.033 14.9 6.3 1.4 9.6 0.2 2.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Bap31_Bap29_C PF18035.1 PSC73000.1 - 0.06 13.4 0.6 0.23 11.5 0.6 2.1 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain BLOC1_2 PF10046.9 PSC73000.1 - 1.9 8.8 6.6 0.49 10.7 0.2 3.3 4 0 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliD_N PF02465.18 PSC73000.1 - 5 7.9 12.6 1.9 9.2 5.7 3.6 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus E1-E2_ATPase PF00122.20 PSC73001.1 - 1.2e-43 148.8 0.5 3.9e-43 147.1 0.3 2.1 2 0 0 2 2 2 1 E1-E2 ATPase RecX PF02631.16 PSC73001.1 - 2e-22 79.9 4.3 2.5e-22 79.6 2.4 2.3 1 1 0 1 1 1 1 RecX family Hydrolase PF00702.26 PSC73001.1 - 3.6e-17 63.3 0.1 2.1e-16 60.9 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PSC73001.1 - 7.7e-12 44.7 0.0 2.7e-11 43.0 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Ysc84 PF04366.12 PSC73001.1 - 1.3e-08 34.6 0.0 3.3e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Las17-binding protein actin regulator Hydrolase_3 PF08282.12 PSC73001.1 - 0.0006 19.6 0.8 0.0036 17.1 0.8 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CPP1-like PF11833.8 PSC73001.1 - 0.0068 16.1 1.6 0.024 14.3 1.6 1.9 1 0 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF3377 PF11857.8 PSC73001.1 - 0.027 14.4 0.1 4.3 7.3 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) Pex14_N PF04695.13 PSC73001.1 - 0.033 14.9 6.3 1.4 9.6 0.2 2.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Bap31_Bap29_C PF18035.1 PSC73001.1 - 0.06 13.4 0.6 0.23 11.5 0.6 2.1 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain BLOC1_2 PF10046.9 PSC73001.1 - 1.9 8.8 6.6 0.49 10.7 0.2 3.3 4 0 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliD_N PF02465.18 PSC73001.1 - 5 7.9 12.6 1.9 9.2 5.7 3.6 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus E1-E2_ATPase PF00122.20 PSC73002.1 - 1.2e-43 148.8 0.5 3.9e-43 147.1 0.3 2.1 2 0 0 2 2 2 1 E1-E2 ATPase RecX PF02631.16 PSC73002.1 - 2e-22 79.9 4.3 2.5e-22 79.6 2.4 2.3 1 1 0 1 1 1 1 RecX family Hydrolase PF00702.26 PSC73002.1 - 3.6e-17 63.3 0.1 2.1e-16 60.9 0.1 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PSC73002.1 - 7.7e-12 44.7 0.0 2.7e-11 43.0 0.0 2.0 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Ysc84 PF04366.12 PSC73002.1 - 1.3e-08 34.6 0.0 3.3e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Las17-binding protein actin regulator Hydrolase_3 PF08282.12 PSC73002.1 - 0.0006 19.6 0.8 0.0036 17.1 0.8 2.1 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase CPP1-like PF11833.8 PSC73002.1 - 0.0068 16.1 1.6 0.024 14.3 1.6 1.9 1 0 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like DUF3377 PF11857.8 PSC73002.1 - 0.027 14.4 0.1 4.3 7.3 0.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3377) Pex14_N PF04695.13 PSC73002.1 - 0.033 14.9 6.3 1.4 9.6 0.2 2.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Bap31_Bap29_C PF18035.1 PSC73002.1 - 0.06 13.4 0.6 0.23 11.5 0.6 2.1 1 0 0 1 1 1 0 Bap31/Bap29 cytoplasmic coiled-coil domain BLOC1_2 PF10046.9 PSC73002.1 - 1.9 8.8 6.6 0.49 10.7 0.2 3.3 4 0 0 4 4 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FliD_N PF02465.18 PSC73002.1 - 5 7.9 12.6 1.9 9.2 5.7 3.6 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DHHC PF01529.20 PSC73003.1 - 1.2e-37 129.0 9.8 1.2e-37 129.0 9.8 1.9 2 0 0 2 2 2 1 DHHC palmitoyltransferase TRP PF06011.12 PSC73003.1 - 1.8 7.2 6.9 1.6 7.4 0.2 2.1 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel tRNA-synt_His PF13393.6 PSC73004.1 - 2.9e-47 161.5 0.0 2.9e-47 161.5 0.0 3.8 3 1 0 3 3 3 1 Histidyl-tRNA synthetase Lyase_aromatic PF00221.19 PSC73004.1 - 1.3e-31 109.8 35.7 1.6e-30 106.2 35.7 2.1 1 1 0 1 1 1 1 Aromatic amino acid lyase adh_short PF00106.25 PSC73004.1 - 5.3e-28 97.8 0.8 6.4e-27 94.3 0.0 2.8 2 1 0 2 2 2 1 short chain dehydrogenase HGTP_anticodon PF03129.20 PSC73004.1 - 9.1e-14 51.4 0.0 3e-13 49.7 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 PSC73004.1 - 1e-05 25.2 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs GDP_Man_Dehyd PF16363.5 PSC73004.1 - 0.00087 18.8 0.0 0.0018 17.7 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PSC73004.1 - 0.0093 15.4 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family tRNA-synt_2b PF00587.25 PSC73004.1 - 0.021 14.8 0.0 0.055 13.4 0.0 1.6 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) DinB_2 PF12867.7 PSC73005.1 - 0.00086 19.8 0.0 0.0023 18.5 0.0 1.9 1 1 0 1 1 1 1 DinB superfamily HD PF01966.22 PSC73005.1 - 0.0074 16.5 1.3 0.023 14.9 1.3 1.9 1 1 0 1 1 1 1 HD domain TPT PF03151.16 PSC73006.1 - 2.1e-87 293.1 18.6 3.2e-87 292.6 18.6 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family Orn_Arg_deC_N PF02784.16 PSC73006.1 - 2.2e-51 174.6 0.0 3.7e-51 173.9 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 PSC73006.1 - 4.5e-24 84.5 0.0 1e-23 83.4 0.0 1.7 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain EamA PF00892.20 PSC73006.1 - 4.5e-07 30.1 26.1 3.2e-05 24.1 10.2 2.4 2 0 0 2 2 2 2 EamA-like transporter family Ala_racemase_N PF01168.20 PSC73006.1 - 1.1e-06 28.5 0.0 4.3e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 Alanine racemase, N-terminal domain UAA PF08449.11 PSC73006.1 - 0.13 11.4 8.0 0.27 10.4 8.0 1.5 1 0 0 1 1 1 0 UAA transporter family DUF1182 PF06681.13 PSC73006.1 - 0.25 10.9 4.8 0.17 11.5 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1182) RhlB PF12300.8 PSC73007.1 - 0.48 10.5 5.4 0.063 13.4 1.2 1.6 2 0 0 2 2 2 0 ATP-dependent RNA helicase RhlB FAST_1 PF06743.15 PSC73008.1 - 4e-06 26.7 3.1 1 9.4 0.0 5.1 4 1 1 5 5 5 3 FAST kinase-like protein, subdomain 1 CSN7a_helixI PF18392.1 PSC73008.1 - 0.058 13.3 0.1 0.14 12.1 0.1 1.6 1 0 0 1 1 1 0 COP9 signalosome complex subunit 7a helix I domain BTB PF00651.31 PSC73010.1 - 1e-07 32.1 0.0 1.8e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 BTB/POZ domain DEAD PF00270.29 PSC73011.1 - 1.1e-45 155.5 0.0 1.9e-45 154.8 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC73011.1 - 2.5e-22 79.3 0.0 9e-22 77.5 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 PSC73011.1 - 3.1e-15 56.1 0.1 6.7e-15 55.1 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 PSC73011.1 - 3.8e-06 27.0 0.0 8.3e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SUIM_assoc PF16619.5 PSC73011.1 - 0.049 13.7 5.9 2.6 8.2 0.2 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Lysine_decarbox PF03641.14 PSC73011.1 - 0.055 13.6 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 Possible lysine decarboxylase TPR_19 PF14559.6 PSC73012.1 - 5.2e-13 49.3 39.9 8.5e-08 32.6 0.1 7.5 6 1 2 8 8 8 4 Tetratricopeptide repeat TPR_16 PF13432.6 PSC73012.1 - 7.6e-08 32.9 15.4 4.2e-05 24.1 7.8 8.2 6 2 3 9 9 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 PSC73012.1 - 1.7e-05 24.9 18.0 0.18 12.1 3.8 4.4 3 1 1 4 4 4 4 Anaphase-promoting complex, cyclosome, subunit 3 INCA1 PF15142.6 PSC73012.1 - 0.0076 16.3 0.1 0.015 15.3 0.1 1.4 1 0 0 1 1 1 1 INCA1 TPR_8 PF13181.6 PSC73012.1 - 0.026 14.7 10.2 0.97 9.8 0.5 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 PSC73012.1 - 0.027 15.2 0.2 0.027 15.2 0.2 9.6 5 2 7 12 12 11 0 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 PSC73012.1 - 0.038 13.6 0.9 4.5 6.9 0.0 3.7 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) MEDS PF14417.6 PSC73012.1 - 0.04 13.7 0.7 0.3 10.9 0.3 2.4 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain TPR_7 PF13176.6 PSC73012.1 - 0.055 13.5 16.5 0.17 11.9 1.6 6.0 8 1 0 8 8 6 0 Tetratricopeptide repeat DUF4810 PF16068.5 PSC73012.1 - 0.21 12.1 0.7 18 5.9 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4810) TPR_9 PF13371.6 PSC73012.1 - 3.1 8.0 30.4 0.17 12.1 0.9 6.7 5 2 2 7 7 7 0 Tetratricopeptide repeat TPR_11 PF13414.6 PSC73012.1 - 4.7 7.0 11.6 40 4.0 0.0 5.4 6 1 1 7 7 7 0 TPR repeat Nucleotid_trans PF03407.16 PSC73013.1 - 1.7e-53 181.7 0.0 6.6e-27 94.9 0.0 2.3 2 0 0 2 2 2 2 Nucleotide-diphospho-sugar transferase Fer2_3 PF13085.6 PSC73013.1 - 1.1e-14 54.3 0.2 2.3e-14 53.3 0.2 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain ACBP PF00887.19 PSC73013.1 - 1.1e-12 47.9 0.6 3.1e-12 46.5 0.6 1.7 1 0 0 1 1 1 1 Acyl CoA binding protein Glyco_transf_34 PF05637.12 PSC73013.1 - 3.8e-05 23.5 0.0 0.25 11.0 0.0 2.4 2 0 0 2 2 2 2 galactosyl transferase GMA12/MNN10 family Fer4_8 PF13183.6 PSC73013.1 - 0.00011 22.6 4.4 0.00029 21.2 4.4 1.8 1 0 0 1 1 1 1 4Fe-4S dicluster domain O-FucT PF10250.9 PSC73013.1 - 0.00077 19.3 0.1 1.2 8.8 0.0 2.3 2 0 0 2 2 2 2 GDP-fucose protein O-fucosyltransferase Fer4_10 PF13237.6 PSC73013.1 - 0.0012 18.9 3.7 0.003 17.6 3.7 1.7 1 1 0 1 1 1 1 4Fe-4S dicluster domain Fer4_17 PF13534.6 PSC73013.1 - 0.013 16.0 3.8 0.032 14.8 3.8 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer2 PF00111.27 PSC73013.1 - 0.042 13.8 1.1 0.1 12.6 1.1 1.6 1 0 0 1 1 1 0 2Fe-2S iron-sulfur cluster binding domain DUF3357 PF11837.8 PSC73013.1 - 0.14 12.7 1.7 2.4 8.7 0.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) ANAPC_CDC26 PF10471.9 PSC73013.1 - 2.1 9.3 8.5 7.3 7.5 4.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 DUF3886 PF13025.6 PSC73013.1 - 8.9 6.6 9.0 0.17 12.1 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) WD40 PF00400.32 PSC73014.1 - 3.9e-08 33.8 18.9 4.2e-06 27.4 0.0 7.0 7 1 0 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC73014.1 - 0.05 13.9 0.0 0.75 10.1 0.0 2.8 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DUF2722 PF10846.8 PSC73014.1 - 0.31 9.9 9.2 4.6 6.1 7.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Pex14_N PF04695.13 PSC73014.1 - 2.8 8.6 11.8 0.91 10.2 4.3 3.0 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EPL1 PF10513.9 PSC73014.1 - 5.3 7.4 6.2 0.93 9.9 0.7 2.0 2 0 0 2 2 2 0 Enhancer of polycomb-like Iso_dh PF00180.20 PSC73015.1 - 1.4e-105 353.3 0.0 1.7e-105 353.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase SNF2_N PF00176.23 PSC73016.1 - 2.3e-63 214.1 0.1 4e-63 213.3 0.1 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC73016.1 - 2.6e-20 72.8 0.1 8.3e-20 71.2 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 PSC73016.1 - 2.7e-19 68.8 0.2 1.2e-10 41.1 0.0 2.9 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Cytochrom_C PF00034.21 PSC73016.1 - 3.2e-10 41.0 0.0 3.2e-10 41.0 0.0 3.8 4 0 0 4 4 1 1 Cytochrome c DUF4208 PF13907.6 PSC73016.1 - 4.1e-10 39.9 4.2 2.7e-09 37.3 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4208) ResIII PF04851.15 PSC73016.1 - 8.6e-08 32.4 0.0 2.3e-07 31.0 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 PSC73016.1 - 2e-07 30.5 0.0 5.1e-07 29.2 0.0 1.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 Cytochrome_CBB3 PF13442.6 PSC73016.1 - 9.8e-06 25.8 3.0 1.7e-05 25.0 0.6 2.9 2 1 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III SDA1 PF05285.12 PSC73016.1 - 0.049 13.1 11.3 0.14 11.5 11.3 1.7 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 PSC73016.1 - 0.056 11.7 13.7 0.096 10.9 13.7 1.3 1 0 0 1 1 1 0 Nop14-like family Cytochrom_C550 PF14495.6 PSC73016.1 - 0.077 12.7 0.1 0.26 11.0 0.1 1.8 2 0 0 2 2 2 0 Cytochrome c-550 domain BUD22 PF09073.10 PSC73016.1 - 0.11 11.8 8.9 0.27 10.5 8.9 1.6 1 0 0 1 1 1 0 BUD22 SWI2_SNF2 PF18766.1 PSC73016.1 - 0.14 11.8 0.0 0.4 10.3 0.0 1.7 1 0 0 1 1 1 0 SWI2/SNF2 ATPase TFIIF_alpha PF05793.12 PSC73016.1 - 0.14 10.7 13.8 0.35 9.4 13.8 1.6 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pkinase_Tyr PF07714.17 PSC73017.1 - 1.2e-63 214.8 0.0 2e-63 214.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC73017.1 - 5.2e-56 189.9 0.0 8e-56 189.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain EDR1 PF14381.6 PSC73017.1 - 1.6e-43 148.8 0.0 2.4e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Ethylene-responsive protein kinase Le-CTR1 Haspin_kinase PF12330.8 PSC73017.1 - 0.00084 18.4 0.0 0.0036 16.3 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Spt20 PF12090.8 PSC73017.1 - 4.1 7.0 9.8 7 6.2 9.8 1.3 1 0 0 1 1 1 0 Spt20 family Plug_translocon PF10559.9 PSC73019.1 - 0.07 13.0 0.2 0.17 11.7 0.2 1.7 1 0 0 1 1 1 0 Plug domain of Sec61p UNC119_bdg PF15435.6 PSC73020.1 - 0.0072 15.9 0.2 0.011 15.2 0.2 1.3 1 0 0 1 1 1 1 UNC119-binding protein C5orf30 homologue Dynamin_M PF01031.20 PSC73021.1 - 2.7e-84 282.8 0.0 3.9e-84 282.2 0.0 1.2 1 0 0 1 1 1 1 Dynamin central region RTC PF01137.21 PSC73021.1 - 6.1e-67 225.1 0.4 5.3e-34 117.4 0.2 2.3 2 0 0 2 2 2 2 RNA 3'-terminal phosphate cyclase Dynamin_N PF00350.23 PSC73021.1 - 1.2e-54 184.9 0.0 1.7e-54 184.4 0.0 1.3 1 0 0 1 1 1 1 Dynamin family PCO_ADO PF07847.12 PSC73021.1 - 1.5e-51 174.8 0.0 2.4e-51 174.1 0.0 1.2 1 0 0 1 1 1 1 PCO_ADO GED PF02212.18 PSC73021.1 - 2.9e-27 94.6 0.6 5e-27 93.9 0.6 1.4 1 0 0 1 1 1 1 Dynamin GTPase effector domain RTC_insert PF05189.13 PSC73021.1 - 4e-18 65.8 0.3 1.3e-17 64.2 0.3 2.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain MMR_HSR1 PF01926.23 PSC73021.1 - 8e-05 22.7 0.0 0.00016 21.7 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 PSC73021.1 - 0.018 15.5 0.9 4.9 7.5 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain TIP41 PF04176.13 PSC73022.1 - 4.9e-55 185.7 0.0 6.1e-55 185.3 0.0 1.1 1 0 0 1 1 1 1 TIP41-like family MlrC_C PF07171.12 PSC73022.1 - 0.0088 16.2 0.1 0.02 15.0 0.1 1.6 1 0 0 1 1 1 1 MlrC C-terminus DUF4242 PF14026.6 PSC73022.1 - 0.053 13.7 0.3 0.96 9.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4242) SNARE_assoc PF09335.11 PSC73023.1 - 1.2e-21 77.4 6.7 1.2e-21 77.4 6.7 2.1 2 1 1 3 3 3 1 SNARE associated Golgi protein TPR_21 PF09976.9 PSC73023.1 - 0.013 15.2 1.0 0.035 13.8 1.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain CP12 PF02672.15 PSC73023.1 - 0.098 13.4 3.3 0.26 12.1 3.3 1.7 1 0 0 1 1 1 0 CP12 domain Ribosomal_60s PF00428.19 PSC73024.1 - 0.25 12.0 6.2 0.16 12.5 3.3 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein ATG16 PF08614.11 PSC73025.1 - 0.00091 19.5 1.4 0.00091 19.5 1.4 17.2 6 2 11 18 18 18 7 Autophagy protein 16 (ATG16) Glyco_hydro_77 PF02446.17 PSC73026.1 - 2.1e-140 468.7 0.0 2.7e-140 468.4 0.0 1.0 1 0 0 1 1 1 1 4-alpha-glucanotransferase UQ_con PF00179.26 PSC73027.1 - 2.9e-37 127.4 0.0 6.8e-37 126.2 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PX PF00787.24 PSC73027.1 - 4.2e-11 42.8 0.0 9.5e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 PX domain US30 PF17624.2 PSC73027.1 - 0.46 9.5 5.1 1.7 7.6 5.1 2.0 1 0 0 1 1 1 0 Family of unknown function UQ_con PF00179.26 PSC73028.1 - 2.9e-37 127.4 0.0 6.9e-37 126.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PX PF00787.24 PSC73028.1 - 4.3e-11 42.8 0.0 9.7e-11 41.7 0.0 1.6 1 0 0 1 1 1 1 PX domain US30 PF17624.2 PSC73028.1 - 0.47 9.5 5.1 1.7 7.6 5.1 1.9 1 0 0 1 1 1 0 Family of unknown function tRNA-synt_2 PF00152.20 PSC73030.1 - 6.8e-80 268.5 0.0 1.3e-65 221.5 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 PSC73030.1 - 5.7e-07 29.4 0.1 1.2e-06 28.3 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain WHEP-TRS PF00458.20 PSC73030.1 - 0.00049 20.2 9.1 0.0012 18.9 9.1 1.7 1 0 0 1 1 1 1 WHEP-TRS domain End3 PF12761.7 PSC73030.1 - 0.01 16.0 3.9 1.3 9.2 0.2 2.2 2 0 0 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 tRNA-synt_2d PF01409.20 PSC73030.1 - 0.011 15.2 0.0 0.081 12.4 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Spc7 PF08317.11 PSC73030.1 - 0.13 11.1 5.9 1.3 7.9 0.9 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein Mod_r PF07200.13 PSC73030.1 - 0.25 11.5 3.3 1.8 8.7 0.3 2.3 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Csm1_N PF18504.1 PSC73030.1 - 3.6 8.0 8.6 12 6.3 0.9 3.4 3 0 0 3 3 3 0 Csm1 N-terminal domain VOMI PF03762.17 PSC73031.1 - 6.6e-26 91.5 0.1 1.3e-25 90.5 0.1 1.5 1 0 0 1 1 1 1 Vitelline membrane outer layer protein I (VOMI) Oxidored_molyb PF00174.19 PSC73032.1 - 8e-62 207.9 0.0 1.3e-61 207.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 PSC73032.1 - 2.5e-35 121.5 0.1 5.2e-35 120.5 0.1 1.6 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain Cyt-b5 PF00173.28 PSC73032.1 - 9e-15 54.6 0.1 1.5e-14 53.9 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Big_7 PF17957.1 PSC73032.1 - 0.0044 17.8 0.0 0.0098 16.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial Ig domain BNR PF02012.20 PSC73032.1 - 0.09 12.8 0.2 0.27 11.4 0.2 1.9 1 0 0 1 1 1 0 BNR/Asp-box repeat SLT_L PF14718.6 PSC73034.1 - 0.0021 18.1 4.0 0.0021 18.1 4.0 2.9 3 0 0 3 3 3 1 Soluble lytic murein transglycosylase L domain EamA PF00892.20 PSC73035.1 - 4.4e-12 46.3 22.3 2.3e-07 31.1 10.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family MitoNEET_N PF10660.9 PSC73035.1 - 0.094 12.8 0.2 0.79 9.8 0.0 2.6 3 0 0 3 3 3 0 Iron-containing outer mitochondrial membrane protein N-terminus Ribosomal_L6e PF01159.19 PSC73036.1 - 9.2e-36 122.8 1.3 1.2e-35 122.4 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L6e Ribosomal_L6e_N PF03868.15 PSC73036.1 - 4.2 7.7 7.2 0.24 11.7 0.9 2.1 2 0 0 2 2 2 0 Ribosomal protein L6, N-terminal domain F-box-like PF12937.7 PSC73037.1 - 8.9e-05 22.3 0.4 0.00025 20.9 0.4 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PSC73037.1 - 0.031 14.1 0.0 0.097 12.6 0.0 1.8 1 1 0 1 1 1 0 F-box domain rve PF00665.26 PSC73039.1 - 8.3e-19 67.9 0.0 1.8e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC73039.1 - 0.0066 16.2 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain AKAP95 PF04988.12 PSC73040.1 - 0.00078 19.7 0.4 0.0013 19.0 0.4 1.2 1 0 0 1 1 1 1 A-kinase anchoring protein 95 (AKAP95) NPR3 PF03666.13 PSC73040.1 - 0.26 10.0 2.6 0.34 9.7 2.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 PSC73040.1 - 1.6 7.4 7.8 2.6 6.7 7.8 1.2 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 PSC73040.1 - 1.6 9.4 10.0 4 8.1 10.0 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Med15 PF09606.10 PSC73040.1 - 2.3 6.8 31.1 0.061 12.0 24.0 1.7 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Thiolase_N PF00108.23 PSC73041.1 - 6.9e-15 55.1 0.0 2.2e-14 53.4 0.0 1.9 1 0 0 1 1 1 1 Thiolase, N-terminal domain DUF4763 PF15960.5 PSC73041.1 - 0.0072 15.7 0.0 0.019 14.3 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4763) Leu_zip PF15294.6 PSC73041.1 - 0.017 14.6 5.5 3.6 7.0 4.1 2.5 2 0 0 2 2 2 0 Leucine zipper SKA1 PF07160.12 PSC73041.1 - 0.064 13.1 4.1 0.27 11.0 1.6 2.2 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 Phage_tail_APC PF16778.5 PSC73041.1 - 0.08 12.8 0.3 0.08 12.8 0.3 3.1 4 0 0 4 4 4 0 Phage tail assembly chaperone protein PolyA_pol_RNAbd PF12627.7 PSC73041.1 - 0.4 10.5 2.1 1.3 8.8 2.1 1.8 1 0 0 1 1 1 0 Probable RNA and SrmB- binding site of polymerase A Atg14 PF10186.9 PSC73041.1 - 0.85 8.6 8.3 0.17 11.0 2.7 2.0 2 0 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 YabA PF06156.13 PSC73041.1 - 1 10.0 4.1 19 6.0 0.0 2.7 2 0 0 2 2 2 0 Initiation control protein YabA ATP_sub_h PF10775.9 PSC73041.1 - 2.4 8.2 5.0 0.49 10.4 0.9 2.0 2 0 0 2 2 2 0 ATP synthase complex subunit h Fez1 PF06818.15 PSC73041.1 - 2.6 8.5 13.6 16 5.8 10.9 2.3 2 0 0 2 2 2 0 Fez1 SpoU_methylase PF00588.19 PSC73042.1 - 7.1e-33 113.8 1.2 9.5e-33 113.3 0.0 1.9 2 0 0 2 2 2 1 SpoU rRNA Methylase family Thioredoxin PF00085.20 PSC73042.1 - 1e-19 70.4 0.0 1.9e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin NHL PF01436.21 PSC73042.1 - 9.8e-14 50.6 0.1 0.018 15.0 0.0 5.0 5 0 0 5 5 5 4 NHL repeat Thioredoxin_7 PF13899.6 PSC73042.1 - 2.1e-06 27.8 0.0 9.1e-06 25.8 0.0 2.1 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 PSC73042.1 - 2.9e-06 27.7 0.0 7.1e-06 26.4 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.21 PSC73042.1 - 0.00013 21.9 0.0 0.00084 19.3 0.0 2.2 2 0 0 2 2 2 1 AhpC/TSA family Phytase-like PF13449.6 PSC73042.1 - 0.0023 18.0 0.0 3 7.7 0.0 3.1 2 1 0 2 2 2 2 Esterase-like activity of phytase SGL PF08450.12 PSC73042.1 - 0.0049 16.5 0.0 1.7 8.2 0.0 3.1 2 1 0 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region Redoxin PF08534.10 PSC73042.1 - 0.026 14.2 0.0 0.19 11.4 0.0 2.4 2 0 0 2 2 2 0 Redoxin Thioredox_DsbH PF03190.15 PSC73042.1 - 0.15 12.0 0.0 0.29 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF255 Thioredoxin_8 PF13905.6 PSC73042.1 - 0.19 12.1 0.0 0.6 10.5 0.0 1.9 1 0 0 1 1 1 0 Thioredoxin-like TraF PF13728.6 PSC73042.1 - 0.59 9.9 0.0 0.59 9.9 0.0 3.0 4 0 0 4 4 4 0 F plasmid transfer operon protein PQQ_3 PF13570.6 PSC73042.1 - 2.4 8.7 4.6 1.8 9.2 0.2 3.2 4 0 0 4 4 2 0 PQQ-like domain F-box PF00646.33 PSC73043.1 - 0.00017 21.4 0.1 0.00051 19.8 0.0 1.8 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 PSC73043.1 - 0.00027 20.8 0.1 0.00058 19.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like Transferase PF02458.15 PSC73043.1 - 0.06 12.0 0.0 0.079 11.6 0.0 1.1 1 0 0 1 1 1 0 Transferase family ADH_zinc_N_2 PF13602.6 PSC73044.1 - 9.5e-24 85.0 0.3 5.6e-23 82.4 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 PSC73044.1 - 1.5e-15 57.3 0.3 1.5e-15 57.3 0.3 2.3 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PSC73044.1 - 9.5e-06 25.5 0.0 2.9e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain MATH PF00917.26 PSC73044.1 - 7.2e-05 22.9 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 MATH domain BTB PF00651.31 PSC73044.1 - 0.00011 22.3 0.0 0.00023 21.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Rhodanese PF00581.20 PSC73044.1 - 0.0008 19.9 0.0 0.0021 18.6 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain YAcAr PF10686.9 PSC73044.1 - 0.014 15.3 0.2 0.052 13.5 0.2 2.0 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family ADH_zinc_N_2 PF13602.6 PSC73045.1 - 9.5e-24 85.0 0.3 5.6e-23 82.4 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 PSC73045.1 - 1.5e-15 57.3 0.3 1.5e-15 57.3 0.3 2.3 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PSC73045.1 - 9.5e-06 25.5 0.0 2.9e-05 23.9 0.0 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain MATH PF00917.26 PSC73045.1 - 7.2e-05 22.9 0.0 0.00012 22.2 0.0 1.3 1 0 0 1 1 1 1 MATH domain BTB PF00651.31 PSC73045.1 - 0.00011 22.3 0.0 0.00023 21.4 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Rhodanese PF00581.20 PSC73045.1 - 0.0008 19.9 0.0 0.0021 18.6 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain YAcAr PF10686.9 PSC73045.1 - 0.014 15.3 0.2 0.052 13.5 0.2 2.0 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family CHRD PF07452.12 PSC73046.1 - 2e-38 131.9 4.1 1.2e-18 68.2 0.1 2.7 3 0 0 3 3 3 2 CHRD domain PIF1 PF05970.14 PSC73047.1 - 1.9e-20 73.4 0.0 6.4e-10 38.7 0.0 3.2 3 1 0 3 3 3 2 PIF1-like helicase AAA_30 PF13604.6 PSC73047.1 - 5.9e-08 32.7 18.1 0.00021 21.1 0.0 4.1 3 1 1 4 4 4 3 AAA domain AAA_19 PF13245.6 PSC73047.1 - 0.00039 20.8 0.0 0.007 16.7 0.0 2.6 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 PSC73047.1 - 0.0012 18.6 0.3 0.0012 18.6 0.3 2.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain Herpes_Helicase PF02689.14 PSC73047.1 - 0.015 13.3 0.0 0.042 11.8 0.0 1.6 2 0 0 2 2 2 0 Helicase Viral_helicase1 PF01443.18 PSC73047.1 - 0.23 11.2 0.0 3.7 7.2 0.0 2.1 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 PSC73047.1 - 0.24 11.2 3.8 0.3 10.9 0.4 2.6 3 0 0 3 3 3 0 AAA domain Ank_2 PF12796.7 PSC73048.1 - 5.8e-12 46.0 0.1 1.2e-11 45.0 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC73048.1 - 4.7e-10 39.5 0.6 5.1e-06 26.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC73048.1 - 7.5e-10 39.2 0.4 3.2e-06 27.6 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC73048.1 - 1.1e-09 37.7 0.2 0.00049 20.3 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 PSC73048.1 - 2.9e-06 27.5 4.5 0.021 15.2 0.3 3.3 3 0 0 3 3 3 2 Ankyrin repeat DMAP_binding PF06464.11 PSC73048.1 - 5.5 7.9 15.3 0.057 14.2 2.5 2.4 2 0 0 2 2 2 0 DMAP1-binding Domain Ank_2 PF12796.7 PSC73049.1 - 5.7e-12 46.1 0.1 1.2e-11 45.0 0.1 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC73049.1 - 4.7e-10 39.5 0.6 5.1e-06 26.7 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC73049.1 - 7.3e-10 39.2 0.4 3.2e-06 27.6 0.1 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC73049.1 - 1.1e-09 37.7 0.2 0.00049 20.3 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 PSC73049.1 - 2.9e-06 27.5 4.5 0.021 15.2 0.3 3.3 3 0 0 3 3 3 2 Ankyrin repeat DMAP_binding PF06464.11 PSC73049.1 - 5.5 7.8 15.3 0.057 14.2 2.5 2.4 2 0 0 2 2 2 0 DMAP1-binding Domain 2_5_RNA_ligase2 PF13563.6 PSC73052.1 - 0.015 15.2 2.7 0.077 12.9 2.7 2.3 1 1 0 1 1 1 0 2'-5' RNA ligase superfamily PIF1 PF05970.14 PSC73053.1 - 3.1e-54 184.5 0.0 1.9e-40 139.2 0.0 2.9 1 1 1 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 PSC73053.1 - 5.3e-19 68.7 0.0 1.3e-18 67.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PSC73053.1 - 1.3e-07 32.1 1.3 6.6e-07 29.8 0.0 2.6 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.6 PSC73053.1 - 0.00015 22.2 0.5 0.00046 20.6 0.1 2.0 2 0 0 2 2 2 1 AAA ATPase domain Herpes_Helicase PF02689.14 PSC73053.1 - 0.00042 18.4 0.1 0.014 13.4 0.0 2.0 2 0 0 2 2 2 1 Helicase AAA_22 PF13401.6 PSC73053.1 - 0.00057 20.2 0.1 0.002 18.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 PSC73053.1 - 0.0021 18.0 0.0 0.0038 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_7 PF12775.7 PSC73053.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Viral_helicase1 PF01443.18 PSC73053.1 - 0.022 14.5 0.0 2.2 8.0 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Mg_chelatase PF01078.21 PSC73053.1 - 0.024 14.0 0.0 0.044 13.2 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI UvrD_C_2 PF13538.6 PSC73053.1 - 0.024 14.4 0.0 0.06 13.2 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain T2SSE PF00437.20 PSC73053.1 - 0.056 12.5 0.0 0.1 11.7 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 PSC73053.1 - 0.1 12.1 0.0 0.31 10.5 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein DUF2075 PF09848.9 PSC73053.1 - 0.11 11.7 0.1 1.1 8.4 0.1 2.3 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2075) Macin PF14865.6 PSC73053.1 - 0.24 11.9 0.8 0.52 10.9 0.8 1.5 1 0 0 1 1 1 0 Macin LRR_4 PF12799.7 PSC73054.1 - 1.2e-18 66.9 0.8 2.8e-05 24.4 0.1 4.6 4 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC73054.1 - 7e-13 48.1 5.2 8.6e-07 28.6 0.0 3.9 2 2 1 3 3 3 3 Leucine rich repeat LRR_9 PF14580.6 PSC73054.1 - 2.7e-11 43.3 0.0 3.8e-08 33.0 0.0 2.1 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 PSC73054.1 - 0.00021 21.4 6.1 13 6.8 0.2 5.6 6 0 0 6 6 6 1 Leucine Rich Repeat LRR_6 PF13516.6 PSC73054.1 - 0.9 9.8 7.2 12 6.3 0.1 4.0 4 0 0 4 4 4 0 Leucine Rich repeat Ank_3 PF13606.6 PSC73055.1 - 0.076 13.6 0.9 6.7 7.6 0.0 3.8 3 0 0 3 3 3 0 Ankyrin repeat Ank_3 PF13606.6 PSC73056.1 - 0.076 13.6 0.9 6.8 7.6 0.0 3.8 3 0 0 3 3 3 0 Ankyrin repeat DnaJ PF00226.31 PSC73057.1 - 0.00014 21.9 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 PSC73057.1 - 0.0015 18.5 0.0 0.0019 18.2 0.0 1.1 1 0 0 1 1 1 1 Pam16 DUF773 PF05600.12 PSC73058.1 - 1.9e-115 386.5 0.0 2.2e-115 386.3 0.0 1.0 1 0 0 1 1 1 1 CDK5 regulatory subunit-associated protein 3 ADIP PF11559.8 PSC73058.1 - 0.29 11.2 1.9 2.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding PfkB PF00294.24 PSC73059.1 - 3.5e-71 240.0 0.0 4e-71 239.8 0.0 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 PSC73059.1 - 0.0068 15.8 0.0 0.047 13.1 0.0 2.0 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase Branch PF02485.21 PSC73060.1 - 1.2e-32 113.4 0.0 9.6e-32 110.4 0.0 2.1 2 0 0 2 2 2 1 Core-2/I-Branching enzyme DUF2722 PF10846.8 PSC73060.1 - 2.5e-05 23.4 13.2 3.8e-05 22.8 13.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Pex14_N PF04695.13 PSC73060.1 - 0.00083 20.0 12.4 0.0018 19.0 12.4 1.6 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SpoIIP PF07454.11 PSC73060.1 - 0.0017 17.8 7.3 0.0025 17.3 7.3 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) DDHD PF02862.17 PSC73060.1 - 0.003 17.7 0.9 0.0041 17.3 0.9 1.2 1 0 0 1 1 1 1 DDHD domain TFIIA PF03153.13 PSC73060.1 - 0.09 12.8 27.6 0.14 12.1 27.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 PSC73060.1 - 0.095 12.0 9.1 0.15 11.3 9.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) EFTUD2 PF16004.5 PSC73060.1 - 0.1 13.2 9.7 1.5 9.4 10.4 2.0 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus Med15 PF09606.10 PSC73060.1 - 0.18 10.4 24.2 0.26 9.9 24.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Neur_chan_memb PF02932.16 PSC73060.1 - 0.2 11.7 4.2 0.3 11.1 4.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3306 PF11748.8 PSC73060.1 - 0.33 11.8 11.1 0.85 10.5 11.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Ndc1_Nup PF09531.10 PSC73060.1 - 0.33 9.6 4.3 0.44 9.2 4.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Suf PF05843.14 PSC73060.1 - 0.46 10.4 12.1 0.7 9.8 12.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 PSC73060.1 - 0.49 10.0 36.6 0.72 9.4 36.6 1.2 1 0 0 1 1 1 0 Spt20 family eIF3_subunit PF08597.10 PSC73060.1 - 0.63 9.9 11.4 1 9.2 11.4 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit EPL1 PF10513.9 PSC73060.1 - 0.68 10.3 10.2 1.1 9.6 10.2 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Presenilin PF01080.17 PSC73060.1 - 0.83 8.3 12.9 1.2 7.9 12.9 1.1 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 PSC73060.1 - 0.84 8.4 7.7 1.2 7.8 7.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2828 PF11443.8 PSC73060.1 - 0.87 7.6 7.9 1.2 7.1 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) CCDC53 PF10152.9 PSC73060.1 - 1.2 9.6 11.4 2.1 8.8 11.4 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex RR_TM4-6 PF06459.12 PSC73060.1 - 1.2 8.9 9.9 1.8 8.3 9.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 PSC73060.1 - 1.9 7.4 16.0 2.6 6.9 16.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3371 PF11851.8 PSC73060.1 - 2.2 9.4 14.0 5.3 8.2 14.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) CPSF100_C PF13299.6 PSC73060.1 - 2.3 8.4 9.5 3.6 7.7 9.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CobT PF06213.12 PSC73060.1 - 3.2 7.1 19.8 5.2 6.4 19.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PAT1 PF09770.9 PSC73060.1 - 3.2 5.9 18.0 4.6 5.4 18.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PPL5 PF18168.1 PSC73060.1 - 4.1 6.6 7.3 5.9 6.1 7.3 1.1 1 0 0 1 1 1 0 Prim-pol family 5 NPR3 PF03666.13 PSC73060.1 - 4.5 5.9 10.7 6.5 5.4 10.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GREB1 PF15782.5 PSC73060.1 - 5.1 4.1 9.2 6.7 3.7 9.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Gti1_Pac2 PF09729.9 PSC73060.1 - 5.2 7.1 9.2 8.4 6.4 9.2 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family SprA-related PF12118.8 PSC73060.1 - 6.3 5.8 24.8 9.5 5.3 24.8 1.2 1 0 0 1 1 1 0 SprA-related family Band_3_cyto PF07565.13 PSC73060.1 - 6.3 6.5 10.3 9.5 5.9 10.3 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TERB2 PF15101.6 PSC73060.1 - 6.5 6.7 17.7 10 6.1 17.7 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SLC12 PF03522.15 PSC73060.1 - 7.2 5.5 10.6 10 5.0 10.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 PSC73060.1 - 7.5 4.5 12.5 10 4.1 12.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GTA_holin_3TM PF11351.8 PSC73060.1 - 7.7 7.1 7.5 9.9 6.7 5.7 2.2 2 0 0 2 2 1 0 Holin of 3TMs, for gene-transfer release NARP1 PF12569.8 PSC73060.1 - 8.9 5.1 11.8 13 4.6 11.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DUF913 PF06025.12 PSC73060.1 - 9.8 5.0 8.1 15 4.5 8.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Branch PF02485.21 PSC73061.1 - 1.1e-32 113.5 0.0 9.4e-32 110.5 0.0 2.1 2 0 0 2 2 2 1 Core-2/I-Branching enzyme Pex14_N PF04695.13 PSC73061.1 - 0.00083 20.0 12.4 0.0018 19.0 12.4 1.6 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region SpoIIP PF07454.11 PSC73061.1 - 0.0017 17.9 7.3 0.0025 17.3 7.3 1.1 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) DDHD PF02862.17 PSC73061.1 - 0.0029 17.8 0.9 0.004 17.3 0.9 1.2 1 0 0 1 1 1 1 DDHD domain TFIIA PF03153.13 PSC73061.1 - 0.09 12.8 27.6 0.14 12.2 27.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EFTUD2 PF16004.5 PSC73061.1 - 0.098 13.2 9.7 1.5 9.4 10.4 2.0 2 0 0 2 2 2 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus DUF4407 PF14362.6 PSC73061.1 - 0.11 11.9 9.1 0.15 11.4 9.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Med15 PF09606.10 PSC73061.1 - 0.18 10.5 24.2 0.25 10.0 24.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Neur_chan_memb PF02932.16 PSC73061.1 - 0.2 11.7 4.2 0.3 11.1 4.2 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.10 PSC73061.1 - 0.23 10.1 3.8 0.3 9.7 3.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3306 PF11748.8 PSC73061.1 - 0.32 11.9 11.1 0.84 10.5 11.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Suf PF05843.14 PSC73061.1 - 0.45 10.4 12.1 0.7 9.8 12.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Spt20 PF12090.8 PSC73061.1 - 0.48 10.0 36.6 0.71 9.4 36.6 1.2 1 0 0 1 1 1 0 Spt20 family EPL1 PF10513.9 PSC73061.1 - 0.67 10.3 10.2 1.1 9.7 10.2 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF2722 PF10846.8 PSC73061.1 - 0.82 8.5 28.0 1.3 7.9 28.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 PSC73061.1 - 0.82 8.4 12.9 1.2 7.9 12.9 1.1 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 PSC73061.1 - 0.83 8.4 7.7 1.2 7.8 7.7 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF2828 PF11443.8 PSC73061.1 - 0.86 7.6 7.9 1.2 7.2 7.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) eIF3_subunit PF08597.10 PSC73061.1 - 1 9.2 12.1 1.6 8.6 12.1 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit CCDC53 PF10152.9 PSC73061.1 - 1.2 9.6 11.4 2.1 8.8 11.4 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex RR_TM4-6 PF06459.12 PSC73061.1 - 1.2 8.9 9.9 1.8 8.4 9.9 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 PSC73061.1 - 1.8 7.4 16.0 2.6 6.9 16.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF3371 PF11851.8 PSC73061.1 - 2.2 9.4 14.0 5.2 8.2 14.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) CPSF100_C PF13299.6 PSC73061.1 - 2.3 8.4 9.5 3.6 7.7 9.5 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CobT PF06213.12 PSC73061.1 - 3.1 7.1 19.8 5.1 6.4 19.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PAT1 PF09770.9 PSC73061.1 - 3.2 5.9 18.0 4.5 5.4 18.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PPL5 PF18168.1 PSC73061.1 - 4 6.6 7.3 5.8 6.1 7.3 1.1 1 0 0 1 1 1 0 Prim-pol family 5 NPR3 PF03666.13 PSC73061.1 - 4.5 6.0 10.7 6.4 5.5 10.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 GREB1 PF15782.5 PSC73061.1 - 5 4.1 9.2 6.6 3.7 9.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Gti1_Pac2 PF09729.9 PSC73061.1 - 5.2 7.1 9.2 8.3 6.5 9.2 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family SprA-related PF12118.8 PSC73061.1 - 6.2 5.8 24.8 9.3 5.3 24.8 1.2 1 0 0 1 1 1 0 SprA-related family TERB2 PF15101.6 PSC73061.1 - 6.5 6.8 17.7 10 6.1 17.7 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SLC12 PF03522.15 PSC73061.1 - 7.2 5.5 10.6 10 5.0 10.6 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 PSC73061.1 - 7.5 4.5 12.5 10 4.1 12.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GTA_holin_3TM PF11351.8 PSC73061.1 - 7.6 7.1 7.5 9.8 6.7 5.7 2.2 2 0 0 2 2 1 0 Holin of 3TMs, for gene-transfer release NARP1 PF12569.8 PSC73061.1 - 8.8 5.1 11.8 13 4.6 11.8 1.1 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Band_3_cyto PF07565.13 PSC73061.1 - 9 6.0 10.8 13 5.4 10.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF913 PF06025.12 PSC73061.1 - 9.7 5.0 8.1 14 4.5 8.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Kelch_4 PF13418.6 PSC73062.1 - 7.2e-16 57.9 7.6 6.6e-05 22.8 0.1 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 PSC73062.1 - 2e-15 56.3 1.2 0.02 14.9 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 PSC73062.1 - 1.8e-14 53.4 0.9 6e-08 32.7 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 PSC73062.1 - 1.6e-13 50.0 0.3 9.2e-09 34.8 0.2 4.6 4 0 0 4 4 4 2 Kelch motif Collagen PF01391.18 PSC73062.1 - 1.8e-12 46.8 129.7 2.7e-07 30.3 36.8 8.2 4 2 3 7 7 7 4 Collagen triple helix repeat (20 copies) Kelch_2 PF07646.15 PSC73062.1 - 3.2e-12 45.9 0.4 9.4e-05 22.2 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 PSC73062.1 - 1e-07 32.0 1.0 0.00018 21.7 0.2 6.6 8 0 0 8 8 8 2 Galactose oxidase, central domain F-box-like PF12937.7 PSC73062.1 - 0.0023 17.8 0.7 0.0023 17.8 0.7 1.6 2 0 0 2 2 2 1 F-box-like Kelch_4 PF13418.6 PSC73063.1 - 7.2e-16 57.9 7.6 6.6e-05 22.8 0.1 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 PSC73063.1 - 2.1e-15 56.3 1.2 0.02 14.9 0.0 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_6 PF13964.6 PSC73063.1 - 1.8e-14 53.4 0.9 6e-08 32.7 0.0 4.7 5 0 0 5 5 5 2 Kelch motif Kelch_1 PF01344.25 PSC73063.1 - 1.6e-13 50.0 0.3 9.2e-09 34.8 0.2 4.6 4 0 0 4 4 4 2 Kelch motif Collagen PF01391.18 PSC73063.1 - 1.8e-12 46.8 129.7 2.7e-07 30.3 36.8 8.2 4 2 3 7 7 7 4 Collagen triple helix repeat (20 copies) Kelch_2 PF07646.15 PSC73063.1 - 3.2e-12 45.9 0.4 9.4e-05 22.2 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 PSC73063.1 - 1e-07 32.0 1.0 0.00018 21.7 0.2 6.6 8 0 0 8 8 8 2 Galactose oxidase, central domain F-box-like PF12937.7 PSC73063.1 - 0.0023 17.8 0.7 0.0023 17.8 0.7 1.6 2 0 0 2 2 2 1 F-box-like PrgH PF09480.10 PSC73064.1 - 0.2 11.0 4.9 0.38 10.0 4.9 1.4 1 0 0 1 1 1 0 Type III secretion system protein PrgH-EprH (PrgH) NopRA1 PF16201.5 PSC73065.1 - 7.1e-44 149.8 1.7 3.1e-43 147.7 0.0 2.7 3 0 0 3 3 3 1 Nucleolar pre-ribosomal-associated protein 1 Npa1 PF11707.8 PSC73065.1 - 6.4e-27 94.8 0.0 1.1e-26 94.0 0.0 1.3 1 0 0 1 1 1 1 Ribosome 60S biogenesis N-terminal zf-MYND PF01753.18 PSC73066.1 - 2.3e-12 46.8 13.5 3.8e-12 46.1 13.5 1.3 1 0 0 1 1 1 1 MYND finger zf-C6H2 PF15801.5 PSC73066.1 - 0.021 15.2 7.5 0.045 14.0 7.5 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding PolC_DP2 PF03833.13 PSC73066.1 - 0.17 9.7 2.0 0.23 9.3 2.0 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 ALG3 PF05208.13 PSC73067.1 - 1.2e-129 432.9 0.1 1.4e-129 432.6 0.1 1.1 1 0 0 1 1 1 1 ALG3 protein DUF4575 PF15143.6 PSC73067.1 - 0.025 14.8 0.7 0.025 14.8 0.7 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4575) FA_desaturase PF00487.24 PSC73069.1 - 2.3e-30 106.3 12.5 2.3e-30 106.3 12.5 2.8 3 0 0 3 3 3 1 Fatty acid desaturase NuA4 PF09340.10 PSC73070.1 - 8.8e-12 44.7 0.6 1.1e-11 44.5 0.6 1.1 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 NuA4 PF09340.10 PSC73071.1 - 9.9e-14 51.0 0.6 1.2e-13 50.7 0.6 1.1 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 MFS_1 PF07690.16 PSC73072.1 - 3.4e-27 95.3 43.1 3.4e-27 95.3 43.1 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily OATP PF03137.20 PSC73072.1 - 1.2e-21 76.6 15.1 1.9e-09 36.4 0.7 3.8 2 2 2 4 4 4 3 Organic Anion Transporter Polypeptide (OATP) family Sugar_tr PF00083.24 PSC73072.1 - 2.6e-07 29.9 23.5 8.3e-07 28.2 23.5 1.8 1 1 0 1 1 1 1 Sugar (and other) transporter UBD PF16455.5 PSC73074.1 - 1.3e-19 70.3 0.0 3.1e-19 69.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-binding domain Amidohydro_2 PF04909.14 PSC73074.1 - 0.013 15.3 2.7 0.14 11.9 0.4 2.9 3 0 0 3 3 3 0 Amidohydrolase 2OG-FeII_Oxy_3 PF13640.6 PSC73074.1 - 0.03 15.2 0.0 0.066 14.1 0.0 1.6 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily UBA PF00627.31 PSC73075.1 - 5.5e-24 83.7 7.1 2e-13 49.9 1.9 2.6 2 0 0 2 2 2 2 UBA/TS-N domain XPC-binding PF09280.11 PSC73075.1 - 1.5e-21 75.8 8.4 3.2e-21 74.8 8.4 1.6 1 0 0 1 1 1 1 XPC-binding domain ubiquitin PF00240.23 PSC73075.1 - 1e-15 57.2 0.1 1.6e-15 56.6 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD_2 PF13881.6 PSC73075.1 - 1.3e-06 28.4 0.0 2.2e-06 27.7 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 PSC73075.1 - 0.00089 19.6 0.1 0.0017 18.7 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD PF11976.8 PSC73075.1 - 0.0025 17.6 0.2 0.0038 17.0 0.2 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBX PF00789.20 PSC73075.1 - 0.092 13.0 0.0 0.16 12.2 0.0 1.3 1 0 0 1 1 1 0 UBX domain UBA_3 PF09288.10 PSC73075.1 - 0.1 12.5 0.1 4.8 7.1 0.1 2.3 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF2407 PF10302.9 PSC73075.1 - 0.22 12.1 0.0 0.43 11.2 0.0 1.4 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain CCDC53 PF10152.9 PSC73075.1 - 0.71 10.3 5.3 3.6 8.0 3.0 2.2 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex FAP PF07174.11 PSC73075.1 - 6.1 6.2 32.3 0.49 9.8 21.2 2.1 2 0 0 2 2 2 0 Fibronectin-attachment protein (FAP) PseudoU_synth_1 PF01416.20 PSC73076.1 - 4.9e-09 36.6 0.0 2.2e-07 31.3 0.0 3.2 3 1 0 3 3 3 1 tRNA pseudouridine synthase GRP PF07172.11 PSC73076.1 - 6 7.6 20.0 11 6.8 20.0 1.3 1 0 0 1 1 1 0 Glycine rich protein family Hydrolase_4 PF12146.8 PSC73077.1 - 1.6e-06 27.5 0.0 0.0095 15.2 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PSC73077.1 - 0.00025 20.8 0.0 0.0007 19.3 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Palm_thioest PF02089.15 PSC73077.1 - 0.012 15.4 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 Palmitoyl protein thioesterase Glucodextran_B PF09136.10 PSC73077.1 - 0.13 12.6 2.4 0.17 12.3 0.4 2.1 2 0 0 2 2 2 0 Glucodextranase, domain B PGAP1 PF07819.13 PSC73077.1 - 0.15 11.7 0.0 0.67 9.6 0.0 2.0 1 1 0 1 1 1 0 PGAP1-like protein mTERF PF02536.14 PSC73079.1 - 4e-06 26.0 0.0 7.1e-06 25.2 0.0 1.3 1 0 0 1 1 1 1 mTERF FH2 PF02181.23 PSC73080.1 - 1.6e-43 149.3 0.0 2.2e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain FH2 PF02181.23 PSC73081.1 - 1.6e-43 149.3 0.0 2.2e-43 148.8 0.0 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain DUF4033 PF13225.6 PSC73082.1 - 5.3e-38 128.9 0.6 7.9e-38 128.3 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) Aldose_epim PF01263.20 PSC73084.1 - 1.1e-48 166.1 0.0 1.3e-48 165.8 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase CP12 PF02672.15 PSC73084.1 - 4e-06 27.5 0.1 8.8e-06 26.4 0.1 1.5 1 0 0 1 1 1 1 CP12 domain GDE_N_bis PF14742.6 PSC73084.1 - 0.01 15.4 0.0 0.035 13.7 0.0 1.8 1 1 0 1 1 1 0 N-terminal domain of (some) glycogen debranching enzymes Glyco_hydro_36N PF16875.5 PSC73084.1 - 0.081 12.5 0.1 0.47 10.0 0.1 2.0 1 1 0 1 1 1 0 Glycosyl hydrolase family 36 N-terminal domain TNV_CP PF03898.13 PSC73084.1 - 0.16 11.2 0.1 5.9 6.1 0.0 2.2 1 1 1 2 2 2 0 Satellite tobacco necrosis virus coat protein Aminotran_3 PF00202.21 PSC73085.1 - 1.6e-88 297.1 0.2 3.4e-88 296.0 0.2 1.5 1 0 0 1 1 1 1 Aminotransferase class-III Cnd1 PF12717.7 PSC73085.1 - 1.5e-48 164.9 0.3 5.4e-46 156.6 0.0 2.7 3 0 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 PSC73085.1 - 3.8e-26 91.9 0.0 1.3e-25 90.2 0.0 2.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT PF02985.22 PSC73085.1 - 7.6e-05 22.6 4.0 13 6.4 0.0 6.1 6 0 0 6 6 6 2 HEAT repeat Adaptin_N PF01602.20 PSC73085.1 - 9e-05 21.2 0.9 0.00023 19.9 0.0 2.1 3 1 0 3 3 3 1 Adaptin N terminal region FANCI_S1 PF14675.6 PSC73085.1 - 0.0075 15.9 0.1 0.017 14.7 0.1 1.5 1 0 0 1 1 1 1 FANCI solenoid 1 HEAT_EZ PF13513.6 PSC73085.1 - 0.032 14.7 13.8 2 9.0 0.0 5.6 5 0 0 5 5 5 0 HEAT-like repeat DUF3427 PF11907.8 PSC73085.1 - 0.078 12.2 0.3 0.14 11.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3427) rve PF00665.26 PSC73086.1 - 1.2e-18 67.4 0.0 2.5e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC73086.1 - 0.01 15.6 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain TFIIA_gamma_C PF02751.14 PSC73087.1 - 2.4e-16 59.6 0.1 3.9e-16 58.9 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 PSC73087.1 - 6.9e-16 58.0 0.1 1.1e-15 57.4 0.1 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Polysacc_deac_1 PF01522.21 PSC73088.1 - 9.3e-09 35.2 0.0 1.7e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Band_7 PF01145.25 PSC73089.1 - 3.9e-23 82.4 2.5 5.6e-23 81.9 2.5 1.3 1 0 0 1 1 1 1 SPFH domain / Band 7 family Porin_3 PF01459.22 PSC73090.1 - 3.4e-30 105.4 10.1 4.2e-30 105.1 10.1 1.1 1 0 0 1 1 1 1 Eukaryotic porin Ank_2 PF12796.7 PSC73091.1 - 5.8e-52 174.2 0.2 5e-14 52.6 0.4 5.1 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC73091.1 - 8.4e-37 125.1 13.6 3.9e-13 49.6 0.4 6.5 4 2 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC73091.1 - 5.4e-32 106.2 15.0 6.5e-05 23.0 0.0 9.2 9 0 0 9 9 9 6 Ankyrin repeat Ank PF00023.30 PSC73091.1 - 1e-30 104.8 31.4 9.1e-05 22.7 0.1 9.2 9 0 0 9 9 9 7 Ankyrin repeat Ank_5 PF13857.6 PSC73091.1 - 1.4e-29 101.8 22.8 2.3e-08 34.1 0.4 7.2 3 2 3 7 7 7 5 Ankyrin repeats (many copies) LRR_4 PF12799.7 PSC73092.1 - 6.6e-12 45.4 6.8 0.00024 21.4 0.3 6.4 6 2 2 8 8 8 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC73092.1 - 1.4e-09 37.5 15.1 0.001 18.8 1.9 6.6 6 1 2 8 8 8 4 Leucine rich repeat LRR_1 PF00560.33 PSC73092.1 - 0.003 17.9 6.9 36 5.5 0.4 6.2 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.6 PSC73092.1 - 0.06 13.4 3.4 60 4.1 0.0 4.4 4 0 0 4 4 4 0 Leucine Rich repeat LRR_4 PF12799.7 PSC73093.1 - 3.8e-12 46.2 8.5 0.00025 21.3 0.3 7.2 6 3 3 9 9 9 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC73093.1 - 8.9e-12 44.6 13.5 0.0028 17.4 2.2 6.7 5 1 2 8 8 8 4 Leucine rich repeat LRR_1 PF00560.33 PSC73093.1 - 0.0003 20.9 5.0 36 5.4 0.4 6.7 8 0 0 8 8 8 1 Leucine Rich Repeat LRR_6 PF13516.6 PSC73093.1 - 0.023 14.7 2.5 61 4.1 0.0 4.7 5 0 0 5 5 5 0 Leucine Rich repeat ProRS-C_1 PF09180.11 PSC73094.1 - 1.5e-29 102.0 0.9 2e-28 98.4 0.5 2.6 2 0 0 2 2 2 1 Prolyl-tRNA synthetase, C-terminal tRNA-synt_2b PF00587.25 PSC73094.1 - 9.9e-18 64.7 0.0 1.6e-17 64.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 PSC73094.1 - 2.7e-17 62.7 0.0 5.8e-17 61.6 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain zf-MYND PF01753.18 PSC73095.1 - 8.1e-08 32.2 11.6 8.1e-08 32.2 11.6 2.0 2 0 0 2 2 2 1 MYND finger TPR_9 PF13371.6 PSC73095.1 - 0.0031 17.6 4.7 0.0031 17.6 4.7 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat Rhodanese_C PF12368.8 PSC73095.1 - 8.7 6.8 9.7 0.99 9.8 5.2 1.7 2 0 0 2 2 2 0 Rhodanase C-terminal HEAT_2 PF13646.6 PSC73096.1 - 2.2e-39 133.7 20.0 1e-14 54.7 0.1 4.2 2 2 3 5 5 5 5 HEAT repeats HEAT_PBS PF03130.16 PSC73096.1 - 8.2e-24 81.8 13.3 8.6e-06 26.0 0.0 7.1 7 0 0 7 7 7 5 PBS lyase HEAT-like repeat HEAT PF02985.22 PSC73096.1 - 2.2e-10 39.8 4.5 0.14 12.5 0.0 6.6 7 0 0 7 7 7 4 HEAT repeat Cnd1 PF12717.7 PSC73096.1 - 0.0017 18.4 0.1 3 7.8 0.0 4.1 2 2 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 PSC73096.1 - 0.009 16.5 15.2 5.2 7.7 0.2 6.7 6 2 2 8 8 8 3 HEAT-like repeat Arm PF00514.23 PSC73096.1 - 0.012 15.7 0.6 2.8 8.1 0.0 3.1 2 1 1 3 3 3 0 Armadillo/beta-catenin-like repeat DUF2838 PF10998.8 PSC73097.1 - 3.9e-33 114.0 4.4 3.9e-33 114.0 4.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF2838) DUF4211 PF13926.6 PSC73098.1 - 1.7e-11 44.4 0.0 1.7e-11 44.4 0.0 2.8 4 0 0 4 4 4 1 Domain of unknown function (DUF4211) Mpp10 PF04006.12 PSC73098.1 - 9.2 4.6 35.4 0.31 9.4 4.4 3.3 3 0 0 3 3 3 0 Mpp10 protein ABC1 PF03109.16 PSC73099.1 - 7.5e-27 93.9 0.0 9.5e-25 87.1 0.0 2.5 1 1 0 1 1 1 1 ABC1 family WXG100 PF06013.12 PSC73099.1 - 0.14 12.4 6.5 0.13 12.5 3.8 2.3 3 0 0 3 3 3 0 Proteins of 100 residues with WXG SSF PF00474.17 PSC73100.1 - 2.5e-08 33.2 16.9 2.5e-08 33.2 16.9 2.1 3 1 0 3 3 3 1 Sodium:solute symporter family SSF PF00474.17 PSC73101.1 - 2.5e-08 33.2 16.9 2.5e-08 33.2 16.9 2.1 3 1 0 3 3 3 1 Sodium:solute symporter family TBCC PF07986.12 PSC73102.1 - 1.6e-33 115.0 0.0 2.4e-33 114.4 0.0 1.2 1 0 0 1 1 1 1 Tubulin binding cofactor C TBCC_N PF16752.5 PSC73102.1 - 1.5e-18 67.3 0.0 2.2e-18 66.8 0.0 1.3 1 0 0 1 1 1 1 Tubulin-specific chaperone C N-terminal domain RecA PF00154.21 PSC73103.1 - 3.1e-117 390.7 1.5 3.9e-117 390.4 1.5 1.1 1 0 0 1 1 1 1 recA bacterial DNA recombination protein Rad51 PF08423.11 PSC73103.1 - 2.1e-11 43.6 0.0 5.1e-11 42.3 0.0 1.5 1 1 0 1 1 1 1 Rad51 ATPase PF06745.13 PSC73103.1 - 3e-06 26.8 0.1 2e-05 24.0 0.0 2.2 1 1 1 2 2 2 1 KaiC AAA_25 PF13481.6 PSC73103.1 - 0.00059 19.5 0.4 0.002 17.8 0.4 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PSC73103.1 - 0.00088 19.7 2.1 0.00097 19.6 0.1 2.0 3 0 0 3 3 3 1 AAA ATPase domain AAA_24 PF13479.6 PSC73103.1 - 0.003 17.3 0.0 0.005 16.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 PSC73103.1 - 0.0067 16.4 0.0 0.016 15.1 0.0 1.6 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 PSC73103.1 - 0.026 15.0 0.0 0.11 13.0 0.0 2.2 1 1 0 1 1 1 0 ABC transporter MobB PF03205.14 PSC73103.1 - 0.083 12.8 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_35 PF14516.6 PSC73103.1 - 0.091 11.6 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain DUF3235 PF11574.8 PSC73103.1 - 6.1 7.8 9.5 1.7 9.5 6.0 1.9 2 0 0 2 2 1 0 Protein of unknown function (DUF3235) Methyltransf_FA PF12248.8 PSC73104.1 - 2.2e-11 44.0 0.0 3.7e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Farnesoic acid 0-methyl transferase BACK PF07707.15 PSC73104.1 - 2.7e-08 33.9 0.0 6.6e-08 32.6 0.0 1.7 1 1 0 1 1 1 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 PSC73104.1 - 4.3e-06 26.9 0.0 3.5e-05 23.9 0.0 2.1 1 1 1 2 2 2 1 F5/8 type C domain COX16 PF14138.6 PSC73105.1 - 1e-19 70.8 0.0 1.1e-19 70.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 ATPgrasp_YheCD PF14398.6 PSC73105.1 - 0.012 14.9 0.0 0.014 14.7 0.0 1.0 1 0 0 1 1 1 0 YheC/D like ATP-grasp DUF952 PF06108.12 PSC73106.1 - 0.037 14.0 0.0 0.039 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF952) CobW_C PF07683.14 PSC73106.1 - 0.11 12.4 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Cobalamin synthesis protein cobW C-terminal domain Thiolase_N PF00108.23 PSC73107.1 - 1.6e-62 211.2 0.9 2.9e-62 210.4 0.9 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 PSC73107.1 - 2.4e-40 137.0 1.5 1.1e-36 125.1 0.1 2.7 1 1 1 2 2 2 2 Thiolase, C-terminal domain RRM_1 PF00076.22 PSC73107.1 - 2.4e-12 46.5 0.0 8e-05 22.4 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_11 PF17123.5 PSC73107.1 - 3.9e-07 29.7 1.3 3.9e-07 29.7 1.3 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_2 PF13639.6 PSC73107.1 - 1.1e-06 28.8 12.7 2.2e-06 27.9 12.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PSC73107.1 - 1.4e-05 25.3 7.8 3.1e-05 24.2 7.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 PSC73107.1 - 0.003 17.6 1.5 0.0072 16.3 1.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RRM_5 PF13893.6 PSC73107.1 - 0.012 15.2 0.0 0.043 13.4 0.0 1.8 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_5 PF14634.6 PSC73107.1 - 0.19 11.7 10.9 0.35 10.9 10.9 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PSC73107.1 - 0.4 10.6 11.5 0.78 9.6 11.5 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC73107.1 - 1.6 8.7 11.4 3.3 7.6 11.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_1 PF14446.6 PSC73107.1 - 1.6 8.7 9.1 4.6 7.3 8.9 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 PSC73107.1 - 3.6 7.3 8.3 8.2 6.1 8.3 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 PSC73107.1 - 4.9 7.1 12.2 8.9 6.3 12.2 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC73107.1 - 8.1 6.6 12.6 3.6 7.7 9.9 1.8 2 0 0 2 2 1 0 RING-type zinc-finger Ank_2 PF12796.7 PSC73108.1 - 5.2e-62 206.4 2.3 3.4e-16 59.6 0.0 6.2 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC73108.1 - 6.9e-47 157.2 6.4 6.3e-08 33.0 0.0 9.9 4 1 7 11 11 11 9 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC73108.1 - 2.6e-45 151.9 21.2 1.2e-09 38.2 0.0 10.7 4 3 8 12 12 12 10 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC73108.1 - 8.1e-36 118.0 15.4 0.00087 19.6 0.0 13.0 13 1 0 13 13 13 10 Ankyrin repeat Ank PF00023.30 PSC73108.1 - 1.9e-32 110.3 45.0 1.1e-05 25.7 0.0 14.1 13 2 1 14 14 14 10 Ankyrin repeat Ser_hydrolase PF06821.13 PSC73108.1 - 1.3 8.9 3.9 4.7 7.0 0.1 3.3 2 2 1 3 3 3 0 Serine hydrolase Cmc1 PF08583.10 PSC73109.1 - 0.00024 21.1 0.0 0.00028 20.9 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF2730 PF10805.8 PSC73109.1 - 0.19 11.8 0.0 0.21 11.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) Pyrid_oxidase_2 PF13883.6 PSC73110.1 - 5.1e-46 156.7 0.0 6.1e-46 156.5 0.0 1.0 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase Erythro_esteras PF05139.14 PSC73112.1 - 9e-100 334.8 0.1 1e-99 334.6 0.1 1.0 1 0 0 1 1 1 1 Erythromycin esterase Myb_DNA-binding PF00249.31 PSC73113.1 - 4.9e-05 23.4 0.0 0.00013 22.1 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain HSA PF07529.13 PSC73113.1 - 6e-05 23.3 0.0 6e-05 23.3 0.0 3.5 3 0 0 3 3 3 1 HSA Myb_DNA-bind_6 PF13921.6 PSC73113.1 - 0.00036 20.7 0.0 0.00098 19.3 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain TTRAP PF14203.6 PSC73113.1 - 0.16 12.0 1.6 0.3 11.1 1.6 1.5 1 0 0 1 1 1 0 Putative tranposon-transfer assisting protein Spermine_synth PF01564.17 PSC73114.1 - 2.9e-61 206.2 0.0 4.4e-61 205.6 0.0 1.3 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 PSC73114.1 - 4.4e-20 71.3 0.0 1.2e-19 69.9 0.0 1.8 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 PSC73114.1 - 0.0001 22.9 0.0 0.00021 21.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 PSC73114.1 - 0.013 16.5 0.0 0.033 15.2 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 PSC73114.1 - 0.031 14.9 0.0 0.078 13.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 PSC73114.1 - 0.098 13.4 0.0 0.37 11.6 0.0 2.0 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_4 PF02390.17 PSC73114.1 - 0.17 11.3 0.0 0.43 10.0 0.0 1.6 2 0 0 2 2 2 0 Putative methyltransferase Pkinase_Tyr PF07714.17 PSC73115.1 - 1.2e-45 155.9 0.0 1.5e-45 155.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC73115.1 - 3.7e-38 131.4 0.0 5.5e-38 130.8 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain zf-RING_2 PF13639.6 PSC73115.1 - 0.0065 16.8 0.5 0.0065 16.8 0.5 2.9 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 PSC73115.1 - 0.0084 16.1 0.2 0.029 14.4 0.2 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PSC73115.1 - 0.023 14.6 1.0 0.19 11.6 0.7 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RWD PF05773.22 PSC73115.1 - 0.044 14.1 0.0 0.084 13.2 0.0 1.5 1 0 0 1 1 1 0 RWD domain zf-rbx1 PF12678.7 PSC73115.1 - 0.058 13.7 1.4 0.2 11.9 1.4 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain GAF_3 PF13492.6 PSC73115.1 - 0.076 13.4 0.0 0.27 11.6 0.0 2.0 1 0 0 1 1 1 0 GAF domain Zn_ribbon_17 PF17120.5 PSC73115.1 - 0.091 12.4 1.5 0.38 10.4 1.5 2.1 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 PSC73115.1 - 0.13 12.2 1.2 0.33 10.9 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PEP-utilizers_C PF02896.18 PSC73116.1 - 2.1e-87 293.0 0.0 3e-87 292.4 0.0 1.2 1 0 0 1 1 1 1 PEP-utilising enzyme, TIM barrel domain PPDK_N PF01326.19 PSC73116.1 - 7.6e-53 179.9 0.0 1.1e-31 110.3 0.0 3.1 1 1 2 3 3 3 3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain PEP-utilizers PF00391.23 PSC73116.1 - 3.8e-27 93.8 0.1 1e-26 92.5 0.1 1.8 1 0 0 1 1 1 1 PEP-utilising enzyme, mobile domain CDP-OH_P_transf PF01066.21 PSC73117.1 - 0.044 14.5 0.2 0.061 14.1 0.2 1.3 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase RecR PF02132.15 PSC73117.1 - 0.19 11.3 6.7 0.3 10.7 6.7 1.5 1 1 0 1 1 1 0 RecR protein NAD_binding_8 PF13450.6 PSC73118.1 - 8.3e-11 42.0 0.9 8.3e-11 42.0 0.9 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.24 PSC73118.1 - 4.2e-05 23.0 1.9 4.2e-05 23.0 1.9 1.8 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase DAO PF01266.24 PSC73118.1 - 0.00074 19.2 5.7 0.0016 18.1 5.7 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 PSC73118.1 - 0.0009 18.6 0.6 0.0009 18.6 0.6 1.7 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 PSC73118.1 - 0.00091 18.5 2.8 0.0014 17.9 1.6 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PSC73118.1 - 0.0044 17.5 1.5 0.0099 16.4 1.5 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PSC73118.1 - 0.025 13.3 2.1 0.043 12.5 2.1 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_3 PF01494.19 PSC73118.1 - 0.13 11.5 4.1 0.23 10.7 4.1 1.3 1 0 0 1 1 1 0 FAD binding domain FMO-like PF00743.19 PSC73118.1 - 0.24 9.7 0.1 0.33 9.3 0.1 1.1 1 0 0 1 1 1 0 Flavin-binding monooxygenase-like GIDA PF01134.22 PSC73118.1 - 9.1 5.2 8.9 0.34 9.9 3.1 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A PfkB PF00294.24 PSC73119.1 - 1.7e-32 113.0 0.3 2.3e-32 112.5 0.3 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase MutS_V PF00488.21 PSC73121.1 - 1.5e-41 142.5 0.0 1.4e-37 129.6 0.0 2.4 2 0 0 2 2 2 2 MutS domain V MutS_I PF01624.20 PSC73121.1 - 7.8e-07 29.3 0.1 0.00066 19.9 0.0 2.5 1 1 1 2 2 2 2 MutS domain I AAA_29 PF13555.6 PSC73121.1 - 0.00093 18.9 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 PSC73121.1 - 0.006 17.1 0.0 0.011 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 PSC73121.1 - 0.048 13.2 0.0 0.15 11.6 0.0 1.8 1 0 0 1 1 1 0 AAA domain GIY-YIG PF01541.24 PSC73121.1 - 0.06 13.6 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 GIY-YIG catalytic domain Cornichon PF03311.14 PSC73122.1 - 9.2e-39 132.5 0.2 1.1e-38 132.2 0.2 1.1 1 0 0 1 1 1 1 Cornichon protein Mak10 PF04112.13 PSC73123.1 - 7.6e-27 93.9 0.0 7.2e-21 74.4 0.0 2.3 1 1 1 2 2 2 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase TSP_1 PF00090.19 PSC73123.1 - 4.6e-12 45.9 29.3 0.001 19.2 4.1 4.1 3 0 0 3 3 3 3 Thrombospondin type 1 domain CCDC53 PF10152.9 PSC73123.1 - 7.3 7.0 8.0 0.34 11.3 0.2 2.7 3 0 0 3 3 3 0 Subunit CCDC53 of WASH complex KDZ PF18758.1 PSC73125.1 - 1.5e-16 60.7 0.3 2.6e-16 59.9 0.3 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase AAA_lid_2 PF17863.1 PSC73125.1 - 7.3e-15 54.6 0.0 2.9e-14 52.7 0.0 2.1 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase PF01078.21 PSC73125.1 - 8.3e-08 31.9 0.1 3e-05 23.5 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 PSC73125.1 - 0.0011 19.4 0.7 0.04 14.3 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain MCM PF00493.23 PSC73125.1 - 0.0024 17.0 0.1 0.05 12.7 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain AAA_5 PF07728.14 PSC73125.1 - 0.005 16.8 0.0 0.77 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF2269 PF10027.9 PSC73125.1 - 0.007 16.4 0.4 0.018 15.1 0.4 1.7 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) Sigma54_activat PF00158.26 PSC73125.1 - 0.0088 15.8 0.0 4.4 7.0 0.0 2.3 2 0 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.13 PSC73125.1 - 0.16 11.1 0.0 0.38 9.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DotA PF11388.8 PSC73125.1 - 0.17 12.1 0.0 7.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Phagosome trafficking protein DotA Lpp-LpqN PF10738.9 PSC73127.1 - 0.13 11.7 0.4 0.18 11.3 0.4 1.2 1 0 0 1 1 1 0 Probable lipoprotein LpqN SPATA3 PF15662.5 PSC73127.1 - 0.38 11.4 6.8 1.6 9.3 6.8 1.8 1 1 0 1 1 1 0 Spermatogenesis-associated protein 3 family LRR_4 PF12799.7 PSC73128.1 - 0.00081 19.7 10.5 10 6.7 0.0 7.1 6 2 2 8 8 8 3 Leucine Rich repeats (2 copies) E1_dh PF00676.20 PSC73129.1 - 6.3e-69 232.2 0.0 9.1e-69 231.7 0.0 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component Transket_pyr PF02779.24 PSC73129.1 - 2.3e-68 229.4 0.0 4.1e-68 228.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 PSC73129.1 - 4.7e-47 159.5 0.0 9.5e-47 158.5 0.0 1.5 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 PSC73129.1 - 2.8e-14 52.4 0.4 2.8e-14 52.4 0.4 2.3 3 0 0 3 3 3 1 2-oxoglutarate dehydrogenase N-terminus F-box PF00646.33 PSC73130.1 - 8.2e-06 25.6 0.2 3.4e-05 23.6 0.2 2.1 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 PSC73130.1 - 0.0058 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 F-box F-box-like PF12937.7 PSC73130.1 - 0.012 15.5 0.4 0.04 13.8 0.4 2.0 1 0 0 1 1 1 0 F-box-like SBP PF03110.14 PSC73131.1 - 4.7e-25 87.7 6.5 8.3e-25 86.9 6.5 1.4 1 0 0 1 1 1 1 SBP domain E1-E2_ATPase PF00122.20 PSC73132.1 - 9.4e-50 168.6 0.3 9.4e-50 168.6 0.3 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 PSC73132.1 - 9.4e-43 146.9 11.9 4.1e-42 144.9 11.9 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 PSC73132.1 - 1.2e-34 118.5 0.1 3.8e-16 59.3 0.0 3.4 3 0 0 3 3 3 3 Heavy-metal-associated domain HAD PF12710.7 PSC73132.1 - 5.8e-06 26.8 0.3 0.00041 20.8 0.1 3.3 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 PSC73132.1 - 8.4e-05 22.4 0.2 0.00016 21.5 0.2 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF3606 PF12244.8 PSC73132.1 - 0.06 13.3 0.5 0.2 11.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3606) FeS_assembly_P PF01883.19 PSC73132.1 - 0.068 13.4 4.4 1.8 8.8 0.2 3.7 3 0 0 3 3 3 0 Iron-sulfur cluster assembly protein Pkinase PF00069.25 PSC73133.1 - 4.9e-55 186.7 0.0 6.4e-55 186.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73133.1 - 2.5e-35 122.0 0.0 3.3e-35 121.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PSC73133.1 - 0.00064 18.6 0.0 0.0011 17.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PSC73133.1 - 0.071 12.5 0.1 0.15 11.4 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PSC73133.1 - 0.083 12.2 0.0 3.8 6.7 0.0 2.2 2 0 0 2 2 2 0 Kinase-like NUDE_C PF04880.13 PSC73133.1 - 3.6 8.0 6.8 7.5 7.0 6.8 1.5 1 0 0 1 1 1 0 NUDE protein, C-terminal conserved region Ins134_P3_kin PF05770.11 PSC73135.1 - 3.6e-35 121.3 0.0 6.8e-18 64.9 0.0 3.2 3 0 0 3 3 3 3 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 PSC73135.1 - 6.4e-15 55.3 0.1 1.2e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain Gly_rich PF12810.7 PSC73135.1 - 1.3 8.8 5.1 0.99 9.3 0.2 2.2 2 0 0 2 2 2 0 Glycine rich protein GTP_EFTU PF00009.27 PSC73136.1 - 6.1e-53 179.2 0.1 9.2e-53 178.7 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 PSC73136.1 - 6.6e-48 161.3 0.9 1.2e-47 160.4 0.9 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 PSC73136.1 - 8e-23 80.3 0.1 1.8e-22 79.1 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PSC73136.1 - 5.5e-08 33.1 0.2 1.1e-07 32.1 0.2 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PSC73136.1 - 2.3e-05 24.4 0.1 0.00011 22.3 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase Ras PF00071.22 PSC73136.1 - 0.00011 21.8 0.0 0.00022 20.9 0.0 1.5 1 0 0 1 1 1 1 Ras family EFG_II PF14492.6 PSC73136.1 - 0.00019 21.4 0.0 0.001 19.1 0.0 2.2 1 1 0 1 1 1 1 Elongation Factor G, domain II RF3_C PF16658.5 PSC73136.1 - 0.0025 17.6 0.0 0.0058 16.4 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain PduV-EutP PF10662.9 PSC73136.1 - 0.0078 16.0 0.0 0.022 14.5 0.0 1.7 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 PSC73136.1 - 0.018 15.1 0.0 0.042 13.9 0.0 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain SRPRB PF09439.10 PSC73136.1 - 0.049 13.1 0.0 0.13 11.6 0.0 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit NSP2-B_epitope PF14757.6 PSC73136.1 - 1.2 8.8 3.2 2 8.1 2.0 1.9 2 0 0 2 2 2 0 Immunogenic region of nsp2 protein of arterivirus polyprotein DUF3429 PF11911.8 PSC73137.1 - 5.6e-34 117.5 13.1 5.6e-34 117.5 13.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3429) Dicer_N PF17895.1 PSC73137.1 - 0.048 13.5 0.7 1 9.2 0.2 2.3 2 0 0 2 2 2 0 Giardia Dicer N-terminal domain RAB3GAP2_N PF14655.6 PSC73138.1 - 2.2e-44 152.4 0.0 1.5e-42 146.3 0.0 2.8 1 1 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus MATH PF00917.26 PSC73138.1 - 1.6e-07 31.5 0.0 2.2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 MATH domain BTB PF00651.31 PSC73138.1 - 0.0017 18.6 0.0 0.0032 17.7 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain ANAPC4_WD40 PF12894.7 PSC73138.1 - 0.11 12.9 0.0 4.6 7.6 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_L20 PF00453.18 PSC73139.1 - 3e-40 136.6 3.9 3.5e-40 136.4 3.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L20 YwhD PF08741.10 PSC73139.1 - 0.075 12.7 0.1 0.089 12.5 0.1 1.2 1 0 0 1 1 1 0 YwhD family ERCC3_RAD25_C PF16203.5 PSC73140.1 - 5.9e-107 356.5 0.0 8.8e-107 355.9 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 PSC73140.1 - 3.2e-35 121.0 0.0 6e-35 120.2 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC73140.1 - 2.1e-13 50.6 0.0 3.4e-13 49.9 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PSC73140.1 - 2.2e-09 37.7 0.1 4.6e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 PSC73140.1 - 9e-07 27.9 0.0 1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain EAP30 PF04157.16 PSC73141.1 - 6.6e-38 130.3 0.0 8.9e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 EAP30/Vps36 family UBA PF00627.31 PSC73141.1 - 0.00035 20.4 0.0 0.00072 19.4 0.0 1.6 1 0 0 1 1 1 1 UBA/TS-N domain EII-Sor PF03609.14 PSC73141.1 - 2.4 7.5 9.3 11 5.3 7.4 2.3 2 0 0 2 2 2 0 PTS system sorbose-specific iic component Filamin PF00630.19 PSC73142.1 - 3.4e-16 59.9 0.0 5.9e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Filamin/ABP280 repeat RRM_1 PF00076.22 PSC73142.1 - 8.9e-10 38.3 0.0 2.1e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Invasin_D3 PF09134.10 PSC73142.1 - 0.0089 16.3 0.0 0.028 14.7 0.0 1.8 1 0 0 1 1 1 1 Invasin, domain 3 YtkA PF13115.6 PSC73142.1 - 0.045 14.3 0.0 0.1 13.2 0.0 1.6 1 0 0 1 1 1 0 YtkA-like RRM_7 PF16367.5 PSC73142.1 - 0.082 13.0 0.0 0.22 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif Filamin PF00630.19 PSC73143.1 - 3.1e-16 60.1 0.0 5.6e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 Filamin/ABP280 repeat RRM_1 PF00076.22 PSC73143.1 - 8.2e-10 38.4 0.0 2e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Invasin_D3 PF09134.10 PSC73143.1 - 0.0081 16.4 0.0 0.027 14.8 0.0 1.8 1 0 0 1 1 1 1 Invasin, domain 3 YtkA PF13115.6 PSC73143.1 - 0.043 14.4 0.0 0.1 13.2 0.0 1.6 1 0 0 1 1 1 0 YtkA-like RRM_7 PF16367.5 PSC73143.1 - 0.078 13.1 0.0 0.21 11.7 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif FHA PF00498.26 PSC73144.1 - 2e-09 37.7 0.0 3.3e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 FHA domain BRX_N PF13713.6 PSC73148.1 - 0.086 12.6 8.3 84 3.1 0.0 6.6 7 0 0 7 7 7 0 Transcription factor BRX N-terminal domain U5_2-snRNA_bdg PF10597.9 PSC73148.1 - 0.13 12.4 1.8 2.8e+02 1.6 0.0 5.1 6 0 0 6 6 6 0 U5-snRNA binding site 2 of PrP8 TFIIA PF03153.13 PSC73149.1 - 0.31 11.0 33.1 0.15 12.1 15.6 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 PSC73149.1 - 8.9 5.1 12.2 27 3.5 10.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) AdoHcyase PF05221.17 PSC73150.1 - 1e-143 478.0 0.0 1.2e-143 477.8 0.0 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 PSC73150.1 - 2e-80 268.6 0.5 3e-80 268.0 0.5 1.3 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 PSC73150.1 - 1e-08 34.8 0.2 1.8e-08 33.9 0.2 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 PSC73150.1 - 0.00027 20.5 0.5 0.00064 19.3 0.5 1.6 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Shikimate_DH PF01488.20 PSC73150.1 - 0.0052 16.9 0.2 0.013 15.5 0.2 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 PSC73150.1 - 0.029 14.8 0.1 0.092 13.2 0.1 1.8 1 0 0 1 1 1 0 Putative NAD(P)-binding THF_DHG_CYH_C PF02882.19 PSC73150.1 - 0.032 13.6 1.2 0.1 11.9 1.2 1.8 1 1 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain TrkA_N PF02254.18 PSC73150.1 - 0.085 13.1 0.7 1.3 9.3 0.7 2.4 1 1 0 1 1 1 0 TrkA-N domain Glyco_hydro_127 PF07944.12 PSC73151.1 - 4.4e-89 299.3 2.6 5.1e-70 236.4 2.0 3.3 3 0 0 3 3 3 3 Beta-L-arabinofuranosidase, GH127 Mito_carr PF00153.27 PSC73151.1 - 1.1e-46 156.6 0.1 7.2e-17 61.1 0.0 3.6 3 0 0 3 3 3 3 Mitochondrial carrier protein Aldedh PF00171.22 PSC73152.1 - 2.4e-135 451.6 0.3 2.4e-135 451.6 0.3 4.9 3 2 2 5 5 5 1 Aldehyde dehydrogenase family Golgin_A5 PF09787.9 PSC73152.1 - 0.0037 16.8 16.1 0.0037 16.8 16.1 4.9 4 1 1 5 5 5 1 Golgin subfamily A member 5 Pox_A_type_inc PF04508.12 PSC73152.1 - 1 9.4 5.6 1.8 8.5 0.2 3.1 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat FlaC_arch PF05377.11 PSC73152.1 - 5.4 7.5 4.4 10 6.6 1.7 2.9 2 1 1 3 3 3 0 Flagella accessory protein C (FlaC) WD40 PF00400.32 PSC73154.1 - 1.5e-08 35.1 3.3 0.093 13.6 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat zf-PARP PF00645.18 PSC73154.1 - 0.00057 20.7 0.1 0.015 16.1 0.2 2.5 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region ANAPC4_WD40 PF12894.7 PSC73154.1 - 0.0024 18.1 0.1 3.9 7.8 0.0 4.4 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain RRM_1 PF00076.22 PSC73154.1 - 0.008 16.0 0.0 0.076 12.8 0.0 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TRAM_LAG1_CLN8 PF03798.16 PSC73155.1 - 9.3e-12 45.1 12.2 1.3e-11 44.7 12.2 1.2 1 0 0 1 1 1 1 TLC domain DUF2722 PF10846.8 PSC73155.1 - 0.00011 21.3 3.7 0.00016 20.8 3.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) SARAF PF06682.12 PSC73155.1 - 0.00057 19.6 6.0 0.0011 18.7 6.0 1.5 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis TFIIA PF03153.13 PSC73155.1 - 0.037 14.0 33.2 0.055 13.5 33.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 PSC73155.1 - 0.059 13.0 22.8 0.12 12.0 22.8 1.4 1 0 0 1 1 1 0 Spt20 family Methyltransf_34 PF11312.8 PSC73155.1 - 0.061 12.6 2.2 0.1 11.8 2.2 1.3 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase eIF-3_zeta PF05091.12 PSC73155.1 - 4.2 6.2 8.9 5.9 5.8 8.9 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) CNDH2_M PF16869.5 PSC73155.1 - 5.6 7.7 7.1 2 9.1 3.2 2.2 2 1 1 3 3 3 0 PF16858 Lin-8 PF03353.15 PSC73155.1 - 6.5 6.2 9.7 9.6 5.7 9.7 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist SMAP PF15477.6 PSC73156.1 - 1.3e-08 35.7 4.1 1.5e-05 25.8 0.0 2.8 3 0 0 3 3 3 2 Small acidic protein family DAGAT PF03982.13 PSC73157.1 - 2.5e-40 138.3 0.0 3.4e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Abhydrolase_1 PF00561.20 PSC73157.1 - 0.019 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC73157.1 - 0.047 13.0 0.1 0.34 10.1 0.1 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DAGAT PF03982.13 PSC73158.1 - 2.5e-40 138.3 0.0 3.4e-40 137.8 0.0 1.1 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Abhydrolase_1 PF00561.20 PSC73158.1 - 0.02 14.6 0.0 0.033 13.8 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC73158.1 - 0.046 13.0 0.1 0.34 10.2 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Y_phosphatase3 PF13350.6 PSC73159.1 - 2.3e-35 122.7 0.1 8.9e-30 104.4 0.0 2.0 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 PSC73159.1 - 5.3e-05 22.8 0.0 8.6e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 PSC73159.1 - 0.00048 19.8 0.0 0.00078 19.1 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Glyco_transf_49 PF13896.6 PSC73160.1 - 8.5e-41 140.4 0.1 2.4e-39 135.6 0.1 2.0 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan DUF3597 PF12200.8 PSC73161.1 - 6.4 7.3 6.2 22 5.6 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3597) PS_Dcarbxylase PF02666.15 PSC73162.1 - 9.9e-57 191.7 0.0 1.4e-56 191.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase EF-hand_5 PF13202.6 PSC73162.1 - 1.3e-08 34.0 0.1 6.6e-06 25.4 0.0 2.7 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 PSC73162.1 - 8.5e-08 31.2 0.0 0.00032 20.0 0.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PSC73162.1 - 1.8e-07 30.5 0.0 0.0011 18.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 PSC73162.1 - 3.6e-06 27.3 0.0 6.6e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 PSC73162.1 - 0.014 15.2 0.0 0.041 13.7 0.0 1.8 1 1 1 2 2 2 0 EF-hand domain pair TerB PF05099.13 PSC73162.1 - 0.099 12.6 0.6 0.23 11.4 0.1 1.8 2 0 0 2 2 2 0 Tellurite resistance protein TerB CxxCxxCC PF03692.15 PSC73163.1 - 6.7e-06 26.7 0.0 1.5e-05 25.5 0.0 1.5 1 0 0 1 1 1 1 Putative zinc- or iron-chelating domain Xan_ur_permease PF00860.20 PSC73164.1 - 1.3e-56 192.0 29.1 3.4e-56 190.6 29.1 1.7 1 1 0 1 1 1 1 Permease family Lipase_GDSL_2 PF13472.6 PSC73165.1 - 2.7e-10 40.9 0.1 2.7e-08 34.4 0.0 3.3 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_2 PF13472.6 PSC73166.1 - 2.8e-10 40.9 0.1 2.8e-08 34.4 0.0 3.3 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL_2 PF13472.6 PSC73167.1 - 2.9e-10 40.8 0.1 2.8e-08 34.4 0.0 3.3 2 1 0 2 2 2 2 GDSL-like Lipase/Acylhydrolase family MBOAT_2 PF13813.6 PSC73168.1 - 2.7e-07 30.8 7.2 5.5e-07 29.8 4.0 2.7 2 1 0 2 2 2 1 Membrane bound O-acyl transferase family DUF4224 PF13986.6 PSC73168.1 - 0.019 14.9 0.0 2.8 7.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4224) MBOAT PF03062.19 PSC73168.1 - 0.047 13.0 1.4 0.76 9.1 1.6 2.2 2 0 0 2 2 2 0 MBOAT, membrane-bound O-acyltransferase family ADP_ribosyl_GH PF03747.14 PSC73170.1 - 5.9e-24 85.3 10.6 7.7e-24 84.9 10.6 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Inositol_P PF00459.25 PSC73171.1 - 2.3e-49 168.4 0.1 3e-49 168.0 0.1 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family SlyX PF04102.12 PSC73172.1 - 1.5 9.5 8.4 6.5 7.5 0.4 3.5 4 0 0 4 4 4 0 SlyX dsrm PF00035.26 PSC73173.1 - 0.04 14.6 0.1 0.068 13.9 0.1 1.4 1 1 0 1 1 1 0 Double-stranded RNA binding motif ETC_C1_NDUFA4 PF04800.12 PSC73174.1 - 7.8e-31 106.2 0.4 9.6e-31 105.9 0.4 1.1 1 0 0 1 1 1 1 ETC complex I subunit conserved region GDP_Man_Dehyd PF16363.5 PSC73175.1 - 4.9e-59 200.4 0.0 8.4e-59 199.6 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PSC73175.1 - 4.2e-48 163.9 0.0 5.8e-48 163.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PSC73175.1 - 1.3e-09 37.5 0.0 1.9e-09 36.9 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 PSC73175.1 - 6.1e-09 35.4 0.0 8.7e-06 25.1 0.0 2.4 1 1 1 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 PSC73175.1 - 4.1e-08 32.7 0.0 9e-08 31.6 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 PSC73175.1 - 3.2e-06 26.5 0.0 0.0012 18.0 0.0 2.6 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein KR PF08659.10 PSC73175.1 - 0.07 13.0 0.1 0.5 10.2 0.0 2.3 3 0 0 3 3 3 0 KR domain Cys_Met_Meta_PP PF01053.20 PSC73175.1 - 0.11 11.0 0.0 10 4.5 0.0 2.1 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme zinc_ribbon_6 PF14599.6 PSC73176.1 - 1e-22 79.9 0.0 1e-22 79.9 0.0 3.6 4 1 0 4 4 4 1 Zinc-ribbon zf-CHY PF05495.12 PSC73176.1 - 3.1e-16 59.6 15.9 3.1e-16 59.6 15.9 3.8 2 1 1 3 3 3 1 CHY zinc finger zf-RING_2 PF13639.6 PSC73176.1 - 3.6e-06 27.2 9.3 3.6e-06 27.2 9.3 4.9 3 1 2 5 5 5 1 Ring finger domain zf-RING_UBOX PF13445.6 PSC73176.1 - 3.7e-06 26.8 4.2 3.7e-06 26.8 4.2 3.6 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_5 PF14634.6 PSC73176.1 - 4.8e-06 26.4 7.7 4.8e-06 26.4 7.7 5.6 2 1 2 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PSC73176.1 - 1.6e-05 24.7 6.8 1.6e-05 24.7 6.8 4.4 4 2 2 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC73176.1 - 0.00033 20.5 8.4 0.00033 20.5 8.4 4.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PSC73176.1 - 0.0011 19.1 9.1 0.0011 19.1 9.1 4.7 5 1 0 5 5 5 1 zinc finger of C3HC4-type, RING DNA_pol_phi PF04931.13 PSC73176.1 - 0.17 10.0 14.4 0.27 9.3 14.4 1.3 1 0 0 1 1 1 0 DNA polymerase phi Nop14 PF04147.12 PSC73176.1 - 2.9 6.0 13.8 4.8 5.3 13.8 1.2 1 0 0 1 1 1 0 Nop14-like family SNF2_N PF00176.23 PSC73177.1 - 1.8e-51 174.9 0.0 2.7e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Trypsin PF00089.26 PSC73177.1 - 5e-43 147.5 0.0 1.4e-29 103.5 0.0 2.5 2 0 0 2 2 2 2 Trypsin Helicase_C PF00271.31 PSC73177.1 - 2.3e-11 44.0 0.0 4.5e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC73177.1 - 3.8e-08 33.5 0.0 6.3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Big_5 PF13205.6 PSC73177.1 - 0.0016 19.1 0.2 0.0042 17.8 0.2 1.7 1 0 0 1 1 1 1 Bacterial Ig-like domain TRP PF06011.12 PSC73177.1 - 0.0038 16.0 14.0 0.015 14.0 1.6 2.5 3 0 0 3 3 3 2 Transient receptor potential (TRP) ion channel DUF2439 PF10382.9 PSC73177.1 - 0.0049 17.2 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) DNA_pol_phi PF04931.13 PSC73177.1 - 0.67 8.0 16.1 1 7.4 16.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 PSC73177.1 - 0.84 9.3 1.8 2.1 8.0 1.8 1.6 1 0 0 1 1 1 0 FAM176 family SNF2_N PF00176.23 PSC73178.1 - 1.8e-51 174.9 0.0 2.8e-51 174.3 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Trypsin PF00089.26 PSC73178.1 - 5.2e-43 147.4 0.0 1.4e-29 103.5 0.0 2.5 2 0 0 2 2 2 2 Trypsin Helicase_C PF00271.31 PSC73178.1 - 2.4e-11 44.0 0.0 4.5e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC73178.1 - 3.9e-08 33.5 0.0 6.4e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Big_5 PF13205.6 PSC73178.1 - 0.0016 19.1 0.2 0.0043 17.7 0.2 1.7 1 0 0 1 1 1 1 Bacterial Ig-like domain TRP PF06011.12 PSC73178.1 - 0.004 16.0 14.0 0.015 14.0 1.6 2.5 3 0 0 3 3 3 2 Transient receptor potential (TRP) ion channel DUF2439 PF10382.9 PSC73178.1 - 0.005 17.1 0.0 0.01 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2439) DNA_pol_phi PF04931.13 PSC73178.1 - 0.68 8.0 16.1 1 7.4 16.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi FAM176 PF14851.6 PSC73178.1 - 0.85 9.3 1.8 2.2 8.0 1.8 1.6 1 0 0 1 1 1 0 FAM176 family HAD_2 PF13419.6 PSC73179.1 - 2.6e-10 40.7 0.0 3.5e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Flu_NS1 PF00600.19 PSC73179.1 - 0.12 11.9 0.1 3.7 7.1 0.0 2.2 2 0 0 2 2 2 0 Influenza non-structural protein (NS1) Helicase_C_3 PF13625.6 PSC73179.1 - 0.15 12.2 0.0 16 5.7 0.0 2.4 1 1 1 2 2 2 0 Helicase conserved C-terminal domain SoPB_HTH PF18090.1 PSC73179.1 - 0.15 12.2 0.0 6.5 7.0 0.0 2.3 1 1 1 2 2 2 0 Centromere-binding protein HTH domain FGE-sulfatase PF03781.16 PSC73180.1 - 5.5e-26 91.7 0.2 1.1e-25 90.7 0.2 1.5 1 1 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Ncstrn_small PF18266.1 PSC73180.1 - 2.2e-20 73.4 0.0 3.4e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 Nicastrin small lobe Nicastrin PF05450.15 PSC73180.1 - 8.3e-20 71.2 0.0 1.5e-19 70.4 0.0 1.4 1 0 0 1 1 1 1 Nicastrin DinB_2 PF12867.7 PSC73180.1 - 2.6e-07 31.2 1.5 4.6e-07 30.4 0.1 2.3 2 0 0 2 2 1 1 DinB superfamily Methyltransf_23 PF13489.6 PSC73180.1 - 6e-07 29.4 0.0 1.2e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC73180.1 - 0.0015 19.2 0.0 0.1 13.3 0.0 3.0 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC73180.1 - 0.0055 17.4 0.0 0.015 16.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain LRR_8 PF13855.6 PSC73180.1 - 0.0086 15.8 4.6 4.5 7.1 0.1 4.4 4 1 0 4 4 4 2 Leucine rich repeat F-box-like PF12937.7 PSC73180.1 - 0.011 15.7 2.8 2.5 8.1 0.2 3.6 3 0 0 3 3 3 0 F-box-like Peptidase_M28 PF04389.17 PSC73180.1 - 0.018 14.7 1.0 0.042 13.5 1.0 1.5 1 0 0 1 1 1 0 Peptidase family M28 Methyltransf_11 PF08241.12 PSC73180.1 - 0.02 15.6 0.0 0.078 13.6 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain F-box PF00646.33 PSC73180.1 - 0.029 14.3 0.0 0.22 11.4 0.0 2.4 2 0 0 2 2 2 0 F-box domain Methyltransf_31 PF13847.6 PSC73180.1 - 0.038 13.8 0.0 0.5 10.2 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain Lustrin_cystein PF14625.6 PSC73180.1 - 0.11 12.8 1.8 0.31 11.4 1.8 1.8 1 0 0 1 1 1 0 Lustrin, cysteine-rich repeated domain C2 PF00168.30 PSC73181.1 - 6.7e-21 74.5 0.0 4.8e-15 55.7 0.0 2.3 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 PSC73181.1 - 3.7e-09 36.3 0.2 1.3e-06 28.0 0.1 2.4 2 0 0 2 2 2 2 Synaptotagmin-like mitochondrial-lipid-binding domain ACPS PF01648.20 PSC73182.1 - 5.3e-12 45.9 0.1 1.9e-11 44.1 0.0 2.0 3 0 0 3 3 3 1 4'-phosphopantetheinyl transferase superfamily ASF1_hist_chap PF04729.13 PSC73183.1 - 5.9e-70 234.1 0.2 6.7e-70 234.0 0.2 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone UPF0154 PF03672.13 PSC73183.1 - 0.18 11.9 0.0 0.36 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0154) Pax7 PF12360.8 PSC73185.1 - 0.12 12.6 0.0 0.19 11.9 0.0 1.3 1 0 0 1 1 1 0 Paired box protein 7 Skp1_POZ PF03931.15 PSC73186.1 - 7.9e-08 32.4 0.0 1.1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.31 PSC73186.1 - 0.095 12.9 0.2 0.2 11.9 0.2 1.6 2 1 0 2 2 2 0 BTB/POZ domain MutS_V PF00488.21 PSC73187.1 - 6.6e-41 140.4 0.0 5.4e-37 127.7 0.0 2.4 2 0 0 2 2 2 2 MutS domain V MutS_I PF01624.20 PSC73187.1 - 1e-13 51.5 0.0 2.1e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain I AAA_29 PF13555.6 PSC73187.1 - 0.0011 18.7 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_23 PF13476.6 PSC73187.1 - 0.0065 17.0 0.0 0.012 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_27 PF13514.6 PSC73187.1 - 0.061 12.9 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF4586 PF15239.6 PSC73188.1 - 4.4e-05 23.8 0.9 7e-05 23.1 0.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4586) Ribosomal_60s PF00428.19 PSC73188.1 - 1.2 9.8 16.5 0.83 10.3 10.3 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein Fasciclin PF02469.22 PSC73189.1 - 5.5e-13 49.3 0.0 9e-13 48.6 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain Pollen_allerg_1 PF01357.21 PSC73189.1 - 7.6e-13 48.3 0.0 1.6e-12 47.3 0.0 1.5 1 0 0 1 1 1 1 Pollen allergen zf-C3HC4_3 PF13920.6 PSC73191.1 - 1.5e-10 40.8 13.1 1.5e-10 40.8 13.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Ank_2 PF12796.7 PSC73191.1 - 2.2e-10 41.0 0.1 2.5e-08 34.4 0.2 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC73191.1 - 1.5e-08 35.0 0.3 0.00046 20.7 0.0 3.3 2 1 2 4 4 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC73191.1 - 4.6e-08 33.2 0.2 0.00027 21.2 0.0 3.8 2 1 3 5 5 5 2 Ankyrin repeats (many copies) Prok-RING_4 PF14447.6 PSC73191.1 - 3.3e-06 26.8 12.0 6.2e-06 26.0 12.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Ank PF00023.30 PSC73191.1 - 0.00014 22.1 6.0 0.61 10.6 0.1 4.3 4 0 0 4 4 4 2 Ankyrin repeat zf-RING_2 PF13639.6 PSC73191.1 - 0.00018 21.8 14.1 0.00037 20.8 14.1 1.6 1 0 0 1 1 1 1 Ring finger domain Ank_3 PF13606.6 PSC73191.1 - 0.0035 17.7 0.0 1.1 10.1 0.0 3.2 2 0 0 2 2 2 1 Ankyrin repeat Roughex PF06020.11 PSC73191.1 - 0.1 11.7 12.4 0.33 10.0 12.4 1.8 1 0 0 1 1 1 0 Drosophila roughex protein zf-RING_5 PF14634.6 PSC73191.1 - 0.15 12.0 12.2 0.39 10.7 12.2 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PSC73191.1 - 1.2 9.0 14.9 2.5 8.0 14.9 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Utp14 PF04615.13 PSC73191.1 - 2.9 6.3 25.5 4.2 5.8 25.5 1.2 1 0 0 1 1 1 0 Utp14 protein Zip PF02535.22 PSC73191.1 - 6.5 5.9 5.8 9.9 5.3 5.8 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter DUF572 PF04502.13 PSC73191.1 - 6.5 6.3 13.2 11 5.5 13.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) SAPS PF04499.15 PSC73191.1 - 7.8 5.2 8.9 13 4.5 8.9 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Ribosomal_L35Ae PF01247.18 PSC73192.1 - 5.1e-43 145.2 0.8 5.8e-43 145.0 0.8 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae PsbP PF01789.16 PSC73193.1 - 7.6e-15 55.4 0.0 1.4e-14 54.5 0.0 1.4 1 1 0 1 1 1 1 PsbP PK PF00224.21 PSC73194.1 - 1.4e-69 234.7 0.0 2e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 PSC73194.1 - 1.3e-18 67.3 1.2 4.7e-18 65.5 0.7 2.1 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain GHMP_kinases_N PF00288.26 PSC73195.1 - 1.7e-12 47.4 0.0 6.7e-12 45.5 0.0 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain DNA_pol_delta_4 PF04081.13 PSC73196.1 - 4.8e-18 65.7 0.0 7.9e-18 65.1 0.0 1.4 1 1 0 1 1 1 1 DNA polymerase delta, subunit 4 DUF1176 PF06674.11 PSC73196.1 - 0.065 12.7 0.4 0.08 12.4 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1176) tRNA-synt_His PF13393.6 PSC73197.1 - 2.9e-47 161.5 0.0 2.9e-47 161.5 0.0 3.8 3 1 0 3 3 3 1 Histidyl-tRNA synthetase Lyase_aromatic PF00221.19 PSC73197.1 - 1.3e-31 109.8 35.7 1.6e-30 106.2 35.7 2.1 1 1 0 1 1 1 1 Aromatic amino acid lyase adh_short PF00106.25 PSC73197.1 - 5.3e-28 97.8 0.8 6.4e-27 94.3 0.0 2.8 2 1 0 2 2 2 1 short chain dehydrogenase HGTP_anticodon PF03129.20 PSC73197.1 - 9.1e-14 51.4 0.0 3e-13 49.7 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 PSC73197.1 - 1e-05 25.2 0.0 1.8e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Anticodon binding domain of tRNAs GDP_Man_Dehyd PF16363.5 PSC73197.1 - 0.00087 18.8 0.0 0.0018 17.7 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 PSC73197.1 - 0.0093 15.4 0.0 0.017 14.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family tRNA-synt_2b PF00587.25 PSC73197.1 - 0.021 14.8 0.0 0.055 13.4 0.0 1.6 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) Peptidase_M50 PF02163.22 PSC73198.1 - 1.3e-56 191.6 0.1 1.7e-56 191.3 0.1 1.1 1 0 0 1 1 1 1 Peptidase family M50 PDZ_6 PF17820.1 PSC73198.1 - 0.0011 18.8 0.4 0.0011 18.8 0.4 2.1 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 PSC73198.1 - 0.0082 16.4 0.1 0.019 15.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain MFS_1 PF07690.16 PSC73199.1 - 0.0094 14.9 0.0 0.01 14.8 0.0 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Ni_hydr_CYTB PF01292.20 PSC73199.1 - 0.036 13.6 0.1 0.036 13.6 0.1 1.0 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 OppC_N PF12911.7 PSC73199.1 - 0.11 12.4 0.6 0.13 12.2 0.6 1.2 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C RVT_1 PF00078.27 PSC73200.1 - 1.3e-15 57.5 0.0 2e-15 56.9 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_lid_2 PF17863.1 PSC73200.1 - 3.9e-15 55.4 0.0 1.7e-14 53.4 0.0 2.2 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase PF01078.21 PSC73200.1 - 0.0005 19.5 0.1 0.0024 17.3 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Flot PF15975.5 PSC73200.1 - 2 8.6 8.4 13 6.0 8.3 2.2 2 0 0 2 2 2 0 Flotillin AAA_lid_2 PF17863.1 PSC73201.1 - 3.2e-15 55.7 0.0 1.5e-14 53.5 0.0 2.2 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase PF01078.21 PSC73201.1 - 0.00031 20.2 0.1 0.0023 17.4 0.0 2.4 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI RVT_1 PF00078.27 PSC73202.1 - 1.3e-15 57.5 0.0 2.1e-15 56.8 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) AAA_lid_2 PF17863.1 PSC73202.1 - 4e-15 55.4 0.0 1.8e-14 53.4 0.0 2.2 1 0 0 1 1 1 1 AAA lid domain Mg_chelatase PF01078.21 PSC73202.1 - 0.00046 19.6 0.1 0.0027 17.1 0.0 2.2 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI Flot PF15975.5 PSC73202.1 - 2.2 8.5 8.5 13 6.0 8.3 2.2 2 0 0 2 2 2 0 Flotillin GLTP PF08718.11 PSC73205.1 - 4.1e-37 127.7 0.0 6.6e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 Glycolipid transfer protein (GLTP) PUB PF09409.10 PSC73205.1 - 1.7e-10 40.7 0.0 3.1e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 PUB domain TFIIA PF03153.13 PSC73205.1 - 1.3 8.9 10.3 0.71 9.8 2.8 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ZZ PF00569.17 PSC73205.1 - 1.7 8.5 8.8 0.19 11.6 3.3 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type WD40 PF00400.32 PSC73206.1 - 2.4e-12 47.1 6.6 0.0029 18.4 0.0 6.5 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC73206.1 - 1.7e-05 25.0 0.0 0.4 11.0 0.0 4.7 4 2 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain tify PF06200.14 PSC73206.1 - 0.029 13.7 0.4 4.2 6.8 0.1 2.5 2 0 0 2 2 2 0 tify domain DUF1918 PF08940.11 PSC73206.1 - 0.1 12.2 0.6 30 4.3 0.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF1918) Isochorismatase PF00857.20 PSC73207.1 - 1.2e-32 113.5 0.0 1.5e-32 113.1 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Glyco_trans_4_2 PF13477.6 PSC73207.1 - 0.0086 16.1 0.0 0.014 15.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_transf_4 PF13439.6 PSC73207.1 - 0.042 13.9 0.3 2.2 8.2 0.1 2.4 2 1 0 2 2 2 0 Glycosyltransferase Family 4 Pyr_redox_2 PF07992.14 PSC73208.1 - 7.3e-54 183.0 2.0 1e-53 182.5 2.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PSC73208.1 - 1.5e-17 63.9 2.7 1.8e-14 54.1 0.0 3.3 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PSC73208.1 - 5.7e-07 29.1 0.2 0.00024 20.5 0.0 2.3 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase UDPG_MGDP_dh_N PF03721.14 PSC73208.1 - 0.0023 17.5 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_8 PF13450.6 PSC73208.1 - 0.011 16.0 0.3 0.21 11.8 0.0 2.7 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 PSC73208.1 - 0.069 13.6 0.4 0.33 11.4 0.1 2.2 2 0 0 2 2 2 0 Putative NAD(P)-binding 3HCDH_N PF02737.18 PSC73208.1 - 0.11 12.4 0.2 0.28 11.0 0.1 1.7 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Trp_halogenase PF04820.14 PSC73208.1 - 0.29 9.9 2.3 2.2 7.0 0.0 2.7 3 0 0 3 3 3 0 Tryptophan halogenase Mito_carr PF00153.27 PSC73209.1 - 1.6e-54 181.8 2.7 1.5e-18 66.5 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1279 PF06916.13 PSC73210.1 - 2.9e-22 79.0 0.4 4.5e-22 78.4 0.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) USP7_ICP0_bdg PF12436.8 PSC73213.1 - 4.7e-57 193.1 0.0 1.6e-56 191.4 0.0 1.9 2 0 0 2 2 2 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.29 PSC73213.1 - 7.3e-45 153.5 0.0 1.2e-44 152.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 PSC73213.1 - 2.6e-36 125.3 0.0 7.2e-35 120.6 0.0 2.9 3 0 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.6 PSC73213.1 - 2.6e-14 53.5 0.0 5.8e-13 49.1 0.0 2.7 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.26 PSC73213.1 - 4e-13 49.5 0.0 1.3e-12 47.8 0.0 1.9 2 0 0 2 2 2 1 MATH domain ubiquitin PF00240.23 PSC73213.1 - 0.0061 16.3 0.0 2.8 7.8 0.0 3.1 3 0 0 3 3 3 1 Ubiquitin family YukD PF08817.10 PSC73213.1 - 0.066 13.9 0.2 13 6.5 0.0 3.5 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD DUF5321 PF17254.2 PSC73213.1 - 0.083 12.3 2.9 1.1 8.7 1.9 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5321) Ino80_Iec3 PF14612.6 PSC73214.1 - 0.014 16.0 3.8 0.027 15.2 3.8 1.3 1 0 0 1 1 1 0 IEC3 subunit of the Ino80 complex, chromatin re-modelling MMR_HSR1_Xtn PF16897.5 PSC73215.1 - 2e-37 127.4 0.1 3.6e-37 126.6 0.1 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 PSC73215.1 - 2.8e-23 81.7 0.0 5.5e-23 80.8 0.0 1.5 1 0 0 1 1 1 1 TGS domain TPT PF03151.16 PSC73215.1 - 7.4e-19 68.2 14.1 1.1e-18 67.7 14.1 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family MMR_HSR1 PF01926.23 PSC73215.1 - 1.1e-17 64.1 0.0 2.3e-17 63.1 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EamA PF00892.20 PSC73215.1 - 2.5e-16 60.1 18.8 3.1e-10 40.4 7.8 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 PSC73215.1 - 2.1e-08 33.7 15.4 3.1e-08 33.2 15.4 1.2 1 0 0 1 1 1 1 UAA transporter family FeoB_N PF02421.18 PSC73215.1 - 5.5e-08 32.5 0.0 1.4e-07 31.2 0.0 1.7 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 PSC73215.1 - 0.0057 15.7 0.2 0.011 14.7 0.2 1.4 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 PSC73215.1 - 0.066 13.3 0.1 2.2 8.3 0.0 2.3 2 0 0 2 2 2 0 Dynamin family AF2331-like PF14556.6 PSC73215.1 - 0.082 13.5 0.0 0.22 12.1 0.0 1.7 1 0 0 1 1 1 0 AF2331-like UQ_con PF00179.26 PSC73216.1 - 1.9e-49 166.9 0.0 2.8e-49 166.4 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme SAND PF01342.21 PSC73216.1 - 1.4e-06 27.9 0.0 2.9e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 SAND domain DUF1860 PF08949.10 PSC73216.1 - 0.2 11.4 1.4 0.38 10.5 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1860) DEAD PF00270.29 PSC73217.1 - 4.9e-28 98.1 0.0 1.3e-27 96.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Lipase_3 PF01764.25 PSC73217.1 - 3.1e-25 88.7 0.0 5.6e-25 87.9 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Helicase_C PF00271.31 PSC73217.1 - 2.2e-18 66.6 0.0 5.4e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.6 PSC73217.1 - 0.0023 17.3 0.0 0.0049 16.3 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit GSHPx PF00255.19 PSC73217.1 - 0.019 14.6 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 Glutathione peroxidase DUF2974 PF11187.8 PSC73217.1 - 0.02 14.5 0.1 0.72 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) ResIII PF04851.15 PSC73217.1 - 0.047 13.7 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SART-1 PF03343.13 PSC73217.1 - 7.6 5.0 5.0 12 4.3 5.0 1.2 1 0 0 1 1 1 0 SART-1 family DEAD PF00270.29 PSC73218.1 - 5.2e-28 98.0 0.0 1.3e-27 96.7 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Lipase_3 PF01764.25 PSC73218.1 - 3.2e-25 88.6 0.0 6e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Helicase_C PF00271.31 PSC73218.1 - 2.2e-18 66.6 0.0 5.5e-18 65.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain CMS1 PF14617.6 PSC73218.1 - 0.0024 17.3 0.0 0.0049 16.2 0.0 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit GSHPx PF00255.19 PSC73218.1 - 0.019 14.5 0.0 1.6 8.3 0.0 2.4 2 0 0 2 2 2 0 Glutathione peroxidase DUF2974 PF11187.8 PSC73218.1 - 0.019 14.5 0.1 0.71 9.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2974) ResIII PF04851.15 PSC73218.1 - 0.047 13.7 0.0 0.091 12.8 0.0 1.3 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit SART-1 PF03343.13 PSC73218.1 - 7.7 4.9 5.0 12 4.3 5.0 1.2 1 0 0 1 1 1 0 SART-1 family Glyco_hydro_18 PF00704.28 PSC73219.1 - 2.2e-10 40.8 0.0 3e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Myb_DNA-binding PF00249.31 PSC73220.1 - 1.2e-12 47.8 0.0 2e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC73220.1 - 5.3e-05 23.4 0.1 8.2e-05 22.8 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain SLIDE PF09111.10 PSC73220.1 - 0.024 14.6 0.0 0.048 13.7 0.0 1.5 1 1 0 1 1 1 0 SLIDE TPR_2 PF07719.17 PSC73221.1 - 1.5e-29 99.7 45.5 0.0016 18.4 0.6 15.8 16 0 0 16 16 15 6 Tetratricopeptide repeat TPR_19 PF14559.6 PSC73221.1 - 1.4e-27 96.0 59.7 2.1e-07 31.3 0.3 12.5 9 4 3 13 13 13 8 Tetratricopeptide repeat TPR_1 PF00515.28 PSC73221.1 - 4.6e-24 83.2 34.7 0.0001 21.9 0.0 11.3 12 0 0 12 12 11 5 Tetratricopeptide repeat TPR_12 PF13424.6 PSC73221.1 - 1.9e-23 82.6 48.0 0.0012 19.1 0.1 11.8 9 3 3 13 13 13 9 Tetratricopeptide repeat TPR_8 PF13181.6 PSC73221.1 - 1.8e-21 74.5 24.5 0.032 14.4 0.0 13.4 15 0 0 15 15 13 6 Tetratricopeptide repeat TPR_11 PF13414.6 PSC73221.1 - 1.8e-20 72.3 16.0 0.0017 18.0 0.1 10.9 11 0 0 11 11 11 4 TPR repeat TPR_14 PF13428.6 PSC73221.1 - 3.9e-17 61.5 81.6 0.0011 19.6 0.3 17.6 15 5 6 21 21 16 5 Tetratricopeptide repeat TPR_16 PF13432.6 PSC73221.1 - 1.5e-16 60.8 70.8 2.3e-07 31.4 0.1 12.0 10 3 2 12 12 10 5 Tetratricopeptide repeat TPR_7 PF13176.6 PSC73221.1 - 6.7e-13 47.7 32.7 0.087 12.9 0.1 12.9 13 0 0 13 13 13 3 Tetratricopeptide repeat TPR_6 PF13174.6 PSC73221.1 - 2.4e-09 37.2 47.2 0.011 16.4 0.1 13.5 16 0 0 16 16 14 4 Tetratricopeptide repeat ANAPC3 PF12895.7 PSC73221.1 - 1.5e-08 34.7 22.9 0.00071 19.8 0.8 6.5 6 1 0 7 7 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 PSC73221.1 - 3.5e-08 33.3 24.3 2.3 8.8 0.1 11.3 12 0 0 12 12 10 3 Tetratricopeptide repeat YfiO PF13525.6 PSC73221.1 - 5e-05 23.1 0.9 0.14 11.9 0.0 3.6 4 0 0 4 4 4 2 Outer membrane lipoprotein TPR_10 PF13374.6 PSC73221.1 - 6.3e-05 22.7 41.5 0.056 13.3 0.4 11.0 13 0 0 13 13 11 3 Tetratricopeptide repeat PknG_TPR PF16918.5 PSC73221.1 - 0.0016 17.2 0.5 0.0016 17.2 0.5 5.4 4 2 2 6 6 6 2 Protein kinase G tetratricopeptide repeat CPL PF08144.11 PSC73221.1 - 0.011 16.0 3.4 0.068 13.5 0.0 2.9 2 0 0 2 2 2 0 CPL (NUC119) domain SHNi-TPR PF10516.9 PSC73221.1 - 0.03 13.8 1.5 2.9 7.4 0.1 3.8 3 0 0 3 3 3 0 SHNi-TPR DUF1844 PF08899.11 PSC73221.1 - 0.059 13.7 3.0 2.7 8.3 0.5 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF1844) TPR_4 PF07721.14 PSC73221.1 - 0.1 13.3 34.2 1.7 9.5 0.1 9.3 9 0 0 9 9 6 0 Tetratricopeptide repeat RR_TM4-6 PF06459.12 PSC73221.1 - 4.4 7.1 12.3 15 5.3 11.3 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 O-FucT PF10250.9 PSC73222.1 - 1.1e-13 51.6 0.0 1.5e-12 47.9 0.0 2.4 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_8 PF01501.20 PSC73222.1 - 0.062 12.8 1.1 3.1 7.3 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferase family 8 CMS1 PF14617.6 PSC73222.1 - 0.53 9.6 1.9 0.78 9.0 1.9 1.2 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Spore_coat_CotO PF14153.6 PSC73223.1 - 0.34 10.8 4.1 0.47 10.4 4.1 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Glyco_tranf_2_4 PF13704.6 PSC73224.1 - 6.8e-06 26.5 0.0 1.5e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 SRCR_2 PF15494.6 PSC73224.1 - 0.12 12.9 0.0 0.28 11.7 0.0 1.5 1 0 0 1 1 1 0 Scavenger receptor cysteine-rich domain Ion_trans PF00520.31 PSC73225.1 - 2.3e-14 53.2 14.8 2.9e-14 52.9 14.8 1.1 1 0 0 1 1 1 1 Ion transport protein PKD_channel PF08016.12 PSC73225.1 - 3.7e-05 22.6 19.8 7.4e-05 21.6 12.3 2.1 1 1 1 2 2 2 2 Polycystin cation channel HSBP1 PF06825.12 PSC73225.1 - 0.033 14.0 0.0 0.34 10.8 0.0 2.2 2 0 0 2 2 2 0 Heat shock factor binding protein 1 ABC_tran_CTD PF16326.5 PSC73225.1 - 0.11 12.8 1.0 5.1 7.4 0.2 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain Tetraspanin PF00335.20 PSC73225.1 - 1.2 8.8 6.6 3.6 7.2 6.7 1.8 1 1 0 1 1 1 0 Tetraspanin family DHHC PF01529.20 PSC73225.1 - 3.1 7.9 13.0 1.6 8.8 4.6 2.4 1 1 1 2 2 2 0 DHHC palmitoyltransferase Gal_Lectin PF02140.18 PSC73226.1 - 6.7e-13 48.9 0.3 0.00013 22.3 0.0 3.8 3 1 1 4 4 4 2 Galactose binding lectin domain Pkinase PF00069.25 PSC73227.1 - 3.1e-49 167.7 0.0 8.7e-49 166.3 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73227.1 - 8.6e-48 162.9 0.1 3.7e-47 160.8 0.1 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PAN_1 PF00024.26 PSC73227.1 - 2.5e-07 30.6 1.6 2.5e-07 30.6 1.6 2.1 2 0 0 2 2 2 1 PAN domain Pkinase_fungal PF17667.1 PSC73227.1 - 2.6e-05 23.2 0.0 3.7e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase PAN_4 PF14295.6 PSC73227.1 - 0.00025 20.9 3.1 0.00025 20.9 3.1 3.2 3 0 0 3 3 3 1 PAN domain APH PF01636.23 PSC73227.1 - 0.026 14.5 0.1 1.7 8.5 0.1 2.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Glyco_transf_92 PF01697.27 PSC73229.1 - 6.7e-16 58.7 0.0 1.6e-15 57.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PSC73229.1 - 9e-09 35.7 0.1 3.6e-08 33.8 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferase family 2 GST_N_3 PF13417.6 PSC73230.1 - 9e-11 42.0 0.0 1.8e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PSC73230.1 - 7.3e-09 35.8 0.0 1.2e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PSC73230.1 - 7.7e-07 29.4 0.0 1.4e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PSC73230.1 - 1.4e-06 28.2 0.3 3.2e-06 27.1 0.3 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PSC73230.1 - 8.5e-05 22.7 0.0 0.00015 21.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 PSC73230.1 - 0.0002 21.9 0.0 0.00033 21.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PSC73230.1 - 0.0027 17.9 0.0 0.004 17.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain KH_1 PF00013.29 PSC73232.1 - 4.1e-56 186.7 0.0 1.7e-12 47.0 0.0 5.6 5 1 0 5 5 5 5 KH domain KH_2 PF07650.17 PSC73232.1 - 5.4e-18 64.6 0.5 0.0069 16.2 0.0 5.2 5 0 0 5 5 5 5 KH domain KH_4 PF13083.6 PSC73232.1 - 1.1e-05 25.2 3.9 1.4 8.9 0.1 5.7 6 0 0 6 6 6 2 KH domain KH_5 PF13184.6 PSC73232.1 - 6.8e-05 22.9 3.4 2 8.6 0.0 5.1 5 0 0 5 5 5 1 NusA-like KH domain Pkinase PF00069.25 PSC73233.1 - 2.7e-48 164.6 0.0 4.3e-45 154.1 0.0 2.2 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73233.1 - 5.5e-19 68.5 0.0 1.1e-18 67.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PSC73233.1 - 5.5e-05 22.6 0.0 9.4e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PSC73233.1 - 0.00097 18.0 0.0 0.0098 14.7 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 PSC73233.1 - 0.095 12.6 0.2 0.095 12.6 0.2 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 PSC73234.1 - 5.8e-48 163.5 0.0 7.6e-48 163.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73234.1 - 2.6e-19 69.5 0.0 4.1e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PSC73234.1 - 5.3e-05 22.7 0.0 8.8e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PSC73234.1 - 0.00092 18.1 0.0 0.0092 14.8 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 PSC73234.1 - 0.09 12.7 0.2 0.09 12.7 0.2 2.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family Pkinase PF00069.25 PSC73235.1 - 9.3e-61 205.5 0.0 1.3e-60 205.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73235.1 - 1.2e-20 73.9 0.0 2.3e-20 73.0 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase EF-hand_1 PF00036.32 PSC73235.1 - 1.1e-05 24.7 0.0 7e-05 22.1 0.0 2.4 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.6 PSC73235.1 - 1.7e-05 24.3 0.0 0.00052 19.7 0.0 3.1 4 0 0 4 4 4 1 EF-hand domain Pkinase_fungal PF17667.1 PSC73235.1 - 5.5e-05 22.1 0.0 8.9e-05 21.4 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase EF-hand_7 PF13499.6 PSC73235.1 - 7.9e-05 23.0 0.0 0.032 14.7 0.0 2.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 PSC73235.1 - 0.00013 21.3 0.5 0.00092 18.6 0.1 2.4 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 PSC73235.1 - 0.00066 19.5 0.1 0.89 9.4 0.0 2.7 2 0 0 2 2 2 2 EF-hand domain pair APH PF01636.23 PSC73235.1 - 0.0011 18.9 0.5 0.1 12.5 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 PSC73235.1 - 0.0011 18.3 0.1 0.0033 16.8 0.1 1.8 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Frankia_peptide PF14407.6 PSC73235.1 - 0.019 14.9 0.4 0.067 13.2 0.1 2.0 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. FTA2 PF13095.6 PSC73235.1 - 0.025 14.2 0.0 0.15 11.7 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 RuvA_C PF07499.13 PSC73235.1 - 0.72 10.4 3.1 32 5.1 0.1 3.2 3 0 0 3 3 3 0 RuvA, C-terminal domain HAT PF02184.16 PSC73236.1 - 4.3e-21 74.6 91.4 1.8e-10 40.6 0.2 16.1 16 2 0 16 16 16 6 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 PSC73236.1 - 3.4e-18 64.8 48.4 0.038 14.8 0.1 13.2 4 4 9 13 13 13 8 Tetratricopeptide repeat TPR_19 PF14559.6 PSC73236.1 - 5.1e-18 65.4 3.8 0.0012 19.3 0.3 7.2 6 1 0 7 7 7 4 Tetratricopeptide repeat Suf PF05843.14 PSC73236.1 - 4.4e-17 63.0 9.4 4e-05 23.8 0.2 6.4 2 2 3 6 6 6 4 Suppressor of forked protein (Suf) TPR_16 PF13432.6 PSC73236.1 - 7.2e-11 42.6 31.6 0.15 12.7 0.8 9.6 9 1 1 10 10 9 4 Tetratricopeptide repeat TPR_8 PF13181.6 PSC73236.1 - 1.7e-09 37.1 4.6 1.4 9.3 0.1 8.7 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_2 PF07719.17 PSC73236.1 - 1.3e-08 34.3 22.8 0.19 11.9 0.0 11.1 13 0 0 13 13 13 3 Tetratricopeptide repeat TPR_17 PF13431.6 PSC73236.1 - 7.9e-08 32.2 0.7 0.034 14.5 0.0 6.3 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 PSC73236.1 - 5.9e-05 23.4 28.6 19 6.2 0.1 11.0 12 1 0 12 12 11 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PSC73236.1 - 6.5e-05 22.9 20.7 0.33 11.0 1.1 6.8 4 3 1 6 6 6 3 Mad3/BUB1 homology region 1 NRDE-2 PF08424.10 PSC73236.1 - 0.0037 16.5 21.3 6.4 5.8 0.0 6.8 2 2 3 5 5 5 3 NRDE-2, necessary for RNA interference TPR_11 PF13414.6 PSC73236.1 - 0.52 10.0 7.1 52 3.6 0.0 5.5 8 0 0 8 8 8 0 TPR repeat TPR_1 PF00515.28 PSC73236.1 - 1.5 8.8 7.4 65 3.6 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat Glyco_tranf_2_4 PF13704.6 PSC73237.1 - 1.9e-08 34.7 0.2 1.2e-07 32.1 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferase family 2 Zn_Tnp_IS1595 PF12760.7 PSC73237.1 - 1.3 9.1 4.6 0.3 11.1 0.6 2.1 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Septin PF00735.18 PSC73238.1 - 2.4e-28 99.2 0.0 8.2e-20 71.2 0.0 2.2 1 1 1 2 2 2 2 Septin Chlorosome_CsmC PF11098.8 PSC73238.1 - 0.0094 15.9 1.4 0.0094 15.9 1.4 1.6 2 0 0 2 2 2 1 Chlorosome envelope protein C YtxH PF12732.7 PSC73238.1 - 0.1 13.1 4.9 0.35 11.4 4.9 1.8 1 0 0 1 1 1 0 YtxH-like protein Mannosyl_trans3 PF11051.8 PSC73239.1 - 1.3e-17 64.1 0.0 7.1e-08 32.1 0.0 2.2 2 0 0 2 2 2 2 Mannosyltransferase putative Lipase_GDSL_2 PF13472.6 PSC73239.1 - 0.0049 17.3 0.3 0.024 15.0 0.1 2.4 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family ANAPC10 PF03256.16 PSC73240.1 - 3.5e-68 228.9 0.0 4.1e-68 228.7 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) F5_F8_type_C PF00754.25 PSC73240.1 - 0.0009 19.4 0.0 0.0013 18.8 0.0 1.3 1 0 0 1 1 1 1 F5/8 type C domain PITH PF06201.13 PSC73240.1 - 0.0048 17.1 0.0 0.0065 16.7 0.0 1.2 1 0 0 1 1 1 1 PITH domain Pkinase PF00069.25 PSC73241.1 - 8.6e-41 140.0 0.0 1.7e-40 139.0 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73241.1 - 5.3e-15 55.4 0.0 8.1e-15 54.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PSC73241.1 - 0.0026 17.1 0.0 0.0048 16.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PSC73241.1 - 0.029 14.3 0.0 0.029 14.3 0.0 3.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 PSC73241.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Baculo_PP31 PF05311.11 PSC73241.1 - 1.2 8.6 2.9 2.1 7.8 2.9 1.2 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) Presenilin PF01080.17 PSC73241.1 - 7 5.3 7.2 11 4.7 7.2 1.3 1 0 0 1 1 1 0 Presenilin CLP_protease PF00574.23 PSC73242.1 - 1.7e-43 148.6 0.0 3e-43 147.8 0.0 1.3 1 0 0 1 1 1 1 Clp protease EF_TS PF00889.19 PSC73243.1 - 3.7e-61 206.4 26.9 2e-30 106.0 7.7 5.4 2 2 0 2 2 2 2 Elongation factor TS S1 PF00575.23 PSC73243.1 - 5.6e-23 81.1 6.1 6.1e-15 55.3 0.7 2.6 2 0 0 2 2 2 2 S1 RNA binding domain UBA PF00627.31 PSC73243.1 - 0.00053 19.8 0.2 0.38 10.7 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain S1_2 PF13509.6 PSC73243.1 - 0.0038 17.2 0.0 3.9 7.6 0.0 3.1 2 0 0 2 2 2 2 S1 domain DPM3 PF08285.11 PSC73243.1 - 0.046 13.9 0.2 0.046 13.9 0.2 3.3 4 0 0 4 4 4 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF692 PF05114.13 PSC73243.1 - 0.067 12.4 0.0 0.14 11.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF692) Kinase-PolyVal PF18762.1 PSC73243.1 - 0.17 11.8 0.1 22 4.9 0.0 2.3 2 0 0 2 2 2 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins DUF416 PF04222.12 PSC73243.1 - 0.22 11.0 6.9 3.3 7.1 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF416) SLS PF14611.6 PSC73243.1 - 0.23 11.3 1.6 12 5.6 0.2 2.3 2 0 0 2 2 2 0 Mitochondrial inner-membrane-bound regulator CsrA PF02599.16 PSC73243.1 - 0.5 10.4 3.5 0.84 9.6 0.1 3.0 3 0 0 3 3 3 0 Global regulator protein family Glyco_tranf_2_4 PF13704.6 PSC73244.1 - 8.3e-10 39.1 0.1 7.9e-08 32.7 0.0 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 2 YEATS PF03366.16 PSC73245.1 - 1.8e-28 98.4 0.2 3.5e-28 97.4 0.2 1.5 1 0 0 1 1 1 1 YEATS family Emaravirus_P4 PF16505.5 PSC73245.1 - 0.075 12.1 0.0 0.1 11.6 0.0 1.1 1 0 0 1 1 1 0 P4 movement protein of Emaravirus, and the 30K superfamily MscS_TM PF12794.7 PSC73246.1 - 0.11 11.4 0.0 0.19 10.5 0.0 1.4 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 JmjC PF02373.22 PSC73248.1 - 2.9e-15 56.7 2.7 7.4e-15 55.4 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 PSC73248.1 - 3.3e-15 56.5 0.0 8.3e-15 55.2 0.0 1.7 2 0 0 2 2 2 1 Cupin-like domain F-box_4 PF15966.5 PSC73248.1 - 0.0044 16.9 2.8 0.073 13.0 0.1 2.5 2 0 0 2 2 2 1 F-box Spem1 PF15670.5 PSC73248.1 - 0.011 15.3 7.4 0.023 14.3 7.4 1.4 1 0 0 1 1 1 0 Spermatid maturation protein 1 F-box-like PF12937.7 PSC73248.1 - 0.015 15.2 2.4 0.056 13.3 2.4 2.1 1 0 0 1 1 1 0 F-box-like F-box PF00646.33 PSC73248.1 - 0.028 14.3 0.9 0.061 13.2 0.9 1.5 1 0 0 1 1 1 0 F-box domain SelP_N PF04592.14 PSC73248.1 - 0.046 13.1 25.1 0.094 12.1 25.1 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Zip PF02535.22 PSC73248.1 - 0.17 11.0 10.3 0.39 9.9 10.3 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter zf-MYND PF01753.18 PSC73249.1 - 2.4e-10 40.3 11.9 2.4e-10 40.3 11.9 2.2 2 0 0 2 2 2 1 MYND finger PBP_N PF17093.5 PSC73249.1 - 0.032 14.5 5.0 0.51 10.6 0.0 2.5 2 1 0 2 2 2 0 Penicillin-binding protein N-terminus SAP PF02037.27 PSC73249.1 - 0.067 13.0 0.0 0.19 11.5 0.0 1.8 1 0 0 1 1 1 0 SAP domain HeH PF12949.7 PSC73249.1 - 0.091 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 HeH/LEM domain HhH-GPD PF00730.25 PSC73250.1 - 2.4e-22 79.5 0.0 4.9e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 PSC73250.1 - 1.7e-14 53.8 0.0 1.6e-13 50.6 0.0 2.4 1 1 0 1 1 1 1 NUDIX domain HHH PF00633.23 PSC73250.1 - 0.0036 17.1 0.0 0.012 15.5 0.0 2.0 1 0 0 1 1 1 1 Helix-hairpin-helix motif MSC PF09402.10 PSC73250.1 - 0.0098 15.4 0.5 0.015 14.8 0.5 1.2 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain S-AdoMet_synt_C PF02773.16 PSC73250.1 - 1.5 8.8 4.2 10 6.1 0.0 2.6 2 0 0 2 2 2 0 S-adenosylmethionine synthetase, C-terminal domain RETICULATA-like PF11891.8 PSC73251.1 - 1.2e-59 201.2 0.0 2e-59 200.4 0.0 1.4 1 0 0 1 1 1 1 Protein RETICULATA-related Pkinase PF00069.25 PSC73251.1 - 1.5e-29 103.2 0.0 2.5e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73251.1 - 7.2e-29 100.9 0.0 1.1e-28 100.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PSC73251.1 - 7.8e-06 24.9 0.0 1.2e-05 24.3 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase GAF_2 PF13185.6 PSC73251.1 - 0.0049 17.2 4.0 0.017 15.4 0.0 3.5 3 0 0 3 3 3 1 GAF domain PAS_4 PF08448.10 PSC73251.1 - 0.011 16.0 0.3 0.042 14.1 0.0 2.1 2 0 0 2 2 1 0 PAS fold PAS_8 PF13188.7 PSC73251.1 - 0.023 14.7 0.0 0.065 13.3 0.0 1.8 1 0 0 1 1 1 0 PAS domain GAF_3 PF13492.6 PSC73251.1 - 0.026 14.9 4.1 0.046 14.1 0.0 2.6 2 0 0 2 2 2 0 GAF domain PAS_9 PF13426.7 PSC73251.1 - 0.028 14.6 0.0 0.056 13.7 0.0 1.4 1 0 0 1 1 1 0 PAS domain Kdo PF06293.14 PSC73251.1 - 0.032 13.6 0.0 0.059 12.7 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAS PF00989.25 PSC73251.1 - 0.17 11.9 0.0 0.4 10.7 0.0 1.6 1 0 0 1 1 1 0 PAS fold RIO1 PF01163.22 PSC73251.1 - 0.22 11.1 0.0 0.39 10.3 0.0 1.3 1 0 0 1 1 1 0 RIO1 family ERM PF00769.19 PSC73251.1 - 1.7 8.4 12.2 2.9 7.6 12.2 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family SAPS PF04499.15 PSC73252.1 - 3.2e-41 141.6 0.0 2.6e-27 95.8 0.0 2.8 2 1 1 3 3 3 2 SIT4 phosphatase-associated protein AAA PF00004.29 PSC73253.1 - 4.7e-13 49.7 0.0 8.8e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PSC73253.1 - 4.5e-11 43.4 0.1 6e-10 39.8 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain BAH PF01426.18 PSC73253.1 - 1e-10 41.5 0.0 4.7e-10 39.4 0.0 2.1 1 1 0 1 1 1 1 BAH domain AAA_22 PF13401.6 PSC73253.1 - 3e-09 37.3 0.0 6.3e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain PHD PF00628.29 PSC73253.1 - 4.2e-09 36.2 6.3 1.1e-08 34.9 6.3 1.8 1 0 0 1 1 1 1 PHD-finger AAA_lid_10 PF17872.1 PSC73253.1 - 2.5e-08 33.9 0.0 5.4e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 AAA lid domain AAA_19 PF13245.6 PSC73253.1 - 0.0065 16.8 0.1 0.028 14.8 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PSC73253.1 - 0.033 14.0 0.1 0.083 12.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain PIF1 PF05970.14 PSC73253.1 - 0.052 12.7 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 PIF1-like helicase DUF2075 PF09848.9 PSC73253.1 - 0.076 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) GvpD PF07088.11 PSC73253.1 - 0.082 11.5 0.0 0.11 11.1 0.0 1.1 1 0 0 1 1 1 0 GvpD gas vesicle protein TIP49 PF06068.13 PSC73253.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain ATPase_2 PF01637.18 PSC73253.1 - 0.13 12.1 0.0 1.3 8.8 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea DUF3388 PF11868.8 PSC73253.1 - 0.17 11.2 0.0 0.33 10.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3388) PHD_2 PF13831.6 PSC73253.1 - 7.1 6.3 7.8 7.8 6.1 0.5 2.3 1 1 1 2 2 2 0 PHD-finger TPR_2 PF07719.17 PSC73254.1 - 0.0016 18.4 0.2 0.0016 18.4 0.2 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat Myb_DNA-binding PF00249.31 PSC73255.1 - 1.5e-46 156.3 11.4 3.1e-17 62.5 0.3 3.4 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC73255.1 - 1.7e-37 127.4 6.5 8.8e-17 61.1 0.4 3.4 1 1 2 3 3 3 3 Myb-like DNA-binding domain DIOX_N PF14226.6 PSC73255.1 - 4.9e-22 78.9 0.0 1.1e-21 77.7 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 PSC73255.1 - 2.1e-21 76.3 0.0 3.9e-21 75.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily SLIDE PF09111.10 PSC73255.1 - 2.1e-06 27.8 0.2 0.16 12.0 0.0 3.5 1 1 2 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 PSC73255.1 - 0.0012 19.0 1.8 1.1 9.5 0.2 3.2 1 1 2 3 3 3 1 SANT/Myb-like domain of DAMP1 Rap1_C PF11626.8 PSC73255.1 - 0.019 15.0 4.3 4.2 7.5 3.2 3.3 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Spt20 PF12090.8 PSC73255.1 - 1.2 8.7 15.1 2.2 7.8 15.1 1.3 1 0 0 1 1 1 0 Spt20 family Myb_DNA-bind_7 PF15963.5 PSC73255.1 - 2.4 8.1 10.8 2.8 7.9 0.5 3.6 2 1 2 4 4 4 0 Myb DNA-binding like zf-rbx1 PF12678.7 PSC73256.1 - 3.6e-22 78.4 2.9 5.7e-22 77.8 2.9 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 PSC73256.1 - 3.7e-15 55.7 5.4 5.5e-15 55.2 5.4 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 PSC73256.1 - 4.6e-10 39.2 3.8 2.2e-08 33.8 1.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC73256.1 - 5.9e-10 39.3 8.4 3.4e-09 36.9 7.2 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PSC73256.1 - 9.2e-09 35.0 0.2 2.1e-08 33.9 0.2 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC73256.1 - 2.3e-07 30.7 0.3 5.5e-07 29.5 0.1 1.8 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PSC73256.1 - 4.7e-06 26.4 3.8 1.1e-05 25.2 0.7 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 PSC73256.1 - 1.9e-05 24.4 3.1 0.00017 21.4 0.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC73256.1 - 2.1e-05 24.4 2.9 5.9e-05 22.9 3.0 1.7 1 1 1 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 PSC73256.1 - 0.00025 20.6 1.6 0.00025 20.6 1.6 2.2 2 1 1 3 3 3 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 PSC73256.1 - 0.00049 19.8 5.5 0.0009 18.9 0.3 2.8 2 1 1 3 3 3 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 PSC73256.1 - 0.0025 17.9 5.1 0.0039 17.3 1.0 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 PSC73256.1 - 0.0037 17.1 0.2 0.007 16.2 0.2 1.5 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 PSC73256.1 - 0.0062 16.3 2.5 0.0072 16.1 0.1 2.0 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 PSC73256.1 - 0.013 15.8 1.6 0.013 15.8 1.6 1.8 2 0 0 2 2 2 0 RING-like domain RINGv PF12906.7 PSC73256.1 - 0.047 13.8 2.1 0.047 13.8 2.1 2.2 2 0 0 2 2 2 0 RING-variant domain DUF2318 PF10080.9 PSC73256.1 - 0.059 13.5 0.4 9.9 6.3 0.0 2.5 2 1 0 2 2 2 0 Predicted membrane protein (DUF2318) zinc_ribbon_16 PF17034.5 PSC73256.1 - 0.1 12.8 3.0 0.16 12.2 2.9 1.6 1 1 0 1 1 1 0 Zinc-ribbon like family Rtf2 PF04641.12 PSC73256.1 - 0.12 11.7 0.0 0.12 11.7 0.0 1.9 2 1 0 2 2 2 0 Rtf2 RING-finger FANCL_C PF11793.8 PSC73256.1 - 0.18 12.0 5.4 0.24 11.6 3.2 2.2 1 1 1 2 2 2 0 FANCL C-terminal domain DiS_P_DiS PF06750.13 PSC73256.1 - 0.21 11.7 2.0 11 6.2 0.1 2.1 2 0 0 2 2 2 0 Bacterial Peptidase A24 N-terminal domain Baculo_RING PF05883.11 PSC73256.1 - 0.55 10.2 2.6 3.7 7.6 2.6 2.0 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-C3H2C3 PF17122.5 PSC73256.1 - 0.55 10.3 6.0 0.28 11.3 2.3 2.2 2 1 0 2 2 2 0 Zinc-finger Myosin_head PF00063.21 PSC73257.1 - 7.3e-228 758.1 0.0 1.1e-227 757.6 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 PSC73257.1 - 0.0014 18.2 26.8 0.0056 16.4 2.5 5.0 4 0 0 4 4 4 3 IQ calmodulin-binding motif AAA_22 PF13401.6 PSC73257.1 - 0.012 15.9 0.6 0.43 10.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain Spc7 PF08317.11 PSC73257.1 - 0.15 10.9 0.2 0.31 9.9 0.2 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein AAA_19 PF13245.6 PSC73257.1 - 0.15 12.3 0.3 0.5 10.7 0.3 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PSC73257.1 - 0.23 11.8 0.0 0.23 11.8 0.0 4.4 4 1 0 4 4 4 0 AAA ATPase domain DUF4106 PF13388.6 PSC73258.1 - 0.14 11.4 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) DUF4666 PF15697.5 PSC73258.1 - 7.5 7.3 6.4 38 5.0 0.1 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4666) Gpr1_Fun34_YaaH PF01184.19 PSC73259.1 - 3.4e-21 75.8 16.1 4.2e-21 75.5 16.1 1.1 1 0 0 1 1 1 1 GPR1/FUN34/yaaH family EMC3_TMCO1 PF01956.16 PSC73259.1 - 0.74 9.5 3.3 1.1 8.9 3.3 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like PEPcase PF00311.17 PSC73260.1 - 5e-273 907.9 0.1 1.9e-211 704.3 0.0 2.1 2 0 0 2 2 2 2 Phosphoenolpyruvate carboxylase Methyltransf_4 PF02390.17 PSC73260.1 - 0.013 15.0 0.0 0.028 13.9 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_25 PF13649.6 PSC73260.1 - 0.1 13.3 0.0 0.84 10.4 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain PEPcase_2 PF14010.6 PSC73260.1 - 0.14 10.6 0.0 3.6 6.0 0.0 2.3 2 0 0 2 2 2 0 Phosphoenolpyruvate carboxylase Thiolase_N PF00108.23 PSC73261.1 - 1.8e-86 289.7 0.9 3.3e-86 288.8 0.9 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 PSC73261.1 - 1.5e-42 144.1 0.1 1.5e-42 144.1 0.1 2.0 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 PSC73261.1 - 0.0002 21.1 1.9 0.00055 19.6 0.7 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 PSC73261.1 - 4 7.4 8.9 14 5.6 0.2 3.5 3 0 0 3 3 3 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GHMP_kinases_N PF00288.26 PSC73262.1 - 8e-11 42.0 4.6 8e-11 42.0 4.6 2.9 4 0 0 4 4 4 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 PSC73262.1 - 8.3e-07 29.3 0.3 8.3e-07 29.3 0.3 2.4 2 0 0 2 2 2 1 GHMP kinases C terminal UQ_con PF00179.26 PSC73263.1 - 2.2e-19 69.5 0.0 4.4e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TFIIA PF03153.13 PSC73263.1 - 0.011 15.8 10.8 0.012 15.7 10.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 PSC73263.1 - 0.023 15.1 2.7 0.032 14.6 2.7 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex RWD PF05773.22 PSC73263.1 - 0.043 14.1 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 RWD domain DUF1180 PF06679.12 PSC73263.1 - 0.12 12.8 5.6 0.16 12.4 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SRP-alpha_N PF04086.13 PSC73263.1 - 0.14 12.1 3.6 0.17 11.7 3.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal NPR1_interact PF15699.5 PSC73263.1 - 0.43 11.2 2.3 0.71 10.5 2.3 1.3 1 0 0 1 1 1 0 NPR1 interacting SARAF PF06682.12 PSC73263.1 - 0.45 10.1 6.0 0.56 9.8 6.0 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Suf PF05843.14 PSC73263.1 - 1.8 8.4 5.5 2.4 8.1 5.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PepSY_TM PF03929.16 PSC73263.1 - 2.3 7.8 6.9 4.3 6.9 6.9 1.5 1 1 0 1 1 1 0 PepSY-associated TM region Pex14_N PF04695.13 PSC73263.1 - 2.3 8.9 17.6 6.1 7.5 17.8 1.6 1 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4366 PF14283.6 PSC73263.1 - 4.4 7.4 5.0 6.9 6.7 5.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) UQ_con PF00179.26 PSC73264.1 - 2.2e-19 69.5 0.0 4.4e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme TFIIA PF03153.13 PSC73264.1 - 0.011 15.8 10.8 0.012 15.7 10.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 PSC73264.1 - 0.023 15.1 2.7 0.032 14.6 2.7 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex RWD PF05773.22 PSC73264.1 - 0.043 14.1 0.0 0.13 12.5 0.0 1.8 2 0 0 2 2 2 0 RWD domain DUF1180 PF06679.12 PSC73264.1 - 0.12 12.8 5.6 0.16 12.4 5.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SRP-alpha_N PF04086.13 PSC73264.1 - 0.14 12.1 3.6 0.17 11.7 3.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal NPR1_interact PF15699.5 PSC73264.1 - 0.43 11.2 2.3 0.71 10.5 2.3 1.3 1 0 0 1 1 1 0 NPR1 interacting SARAF PF06682.12 PSC73264.1 - 0.45 10.1 6.0 0.56 9.8 6.0 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Suf PF05843.14 PSC73264.1 - 1.8 8.4 5.5 2.4 8.1 5.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PepSY_TM PF03929.16 PSC73264.1 - 2.3 7.8 6.9 4.3 6.9 6.9 1.5 1 1 0 1 1 1 0 PepSY-associated TM region Pex14_N PF04695.13 PSC73264.1 - 2.3 8.9 17.6 6.1 7.5 17.8 1.6 1 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4366 PF14283.6 PSC73264.1 - 4.4 7.4 5.0 6.9 6.7 5.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) FA_hydroxylase PF04116.13 PSC73265.1 - 6.4e-15 55.7 6.5 6.4e-15 55.7 6.5 1.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Anth_synt_I_N PF04715.13 PSC73265.1 - 0.026 14.8 0.0 0.042 14.1 0.0 1.4 1 0 0 1 1 1 0 Anthranilate synthase component I, N terminal region zf-RanBP PF00641.18 PSC73267.1 - 0.00016 20.9 0.3 0.00028 20.1 0.3 1.4 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others AP2 PF00847.20 PSC73267.1 - 0.097 12.9 0.0 0.097 12.9 0.0 1.9 2 0 0 2 2 2 0 AP2 domain Met_10 PF02475.16 PSC73269.1 - 1.9e-65 220.4 0.0 2.5e-65 220.0 0.0 1.1 1 0 0 1 1 1 1 Met-10+ like-protein CCDC53 PF10152.9 PSC73269.1 - 0.032 14.7 0.2 0.067 13.6 0.1 1.7 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Methyltransf_23 PF13489.6 PSC73269.1 - 0.065 13.1 0.1 0.17 11.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Suf PF05843.14 PSC73269.1 - 0.083 12.9 2.8 0.14 12.1 2.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CCD48 PF15799.5 PSC73270.1 - 0.65 8.2 3.3 0.87 7.8 3.3 1.0 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 Glycos_transf_3 PF00591.21 PSC73271.1 - 7.8e-87 291.0 5.8 1.1e-86 290.6 5.8 1.2 1 0 0 1 1 1 1 Glycosyl transferase family, a/b domain Glycos_trans_3N PF02885.17 PSC73271.1 - 3.2e-14 52.5 2.3 6.7e-14 51.5 2.3 1.6 1 0 0 1 1 1 1 Glycosyl transferase family, helical bundle domain ELYS PF13934.6 PSC73272.1 - 2.9e-11 43.8 3.1 3.6e-11 43.5 0.0 2.5 3 0 0 3 3 3 1 Nuclear pore complex assembly DUF3449 PF11931.8 PSC73273.1 - 2.1e-71 239.5 0.2 4.4e-71 238.5 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3449) Telomere_Sde2_2 PF13297.6 PSC73273.1 - 5.3e-26 90.1 3.0 1.3e-25 88.8 3.0 1.7 1 0 0 1 1 1 1 Telomere stability C-terminal SF3A3 PF16837.5 PSC73273.1 - 3.3e-23 82.0 0.1 7.2e-23 80.9 0.1 1.6 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 PSC73273.1 - 1.2e-11 44.2 0.4 1.2e-11 44.2 0.4 2.1 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain TerB_C PF15615.6 PSC73273.1 - 0.011 16.0 0.5 0.011 16.0 0.5 2.3 2 0 0 2 2 2 0 TerB-C domain PRP9_N PF16958.5 PSC73273.1 - 3.7 7.5 6.8 0.46 10.5 0.4 2.3 2 1 1 3 3 3 0 Pre-mRNA-splicing factor PRP9 N-terminus Phosphorylase PF00343.20 PSC73274.1 - 7.5e-297 986.4 1.3 1.4e-294 979.0 1.3 2.0 1 1 0 1 1 1 1 Carbohydrate phosphorylase MtN3_slv PF03083.16 PSC73275.1 - 8.7e-29 99.4 6.8 7.8e-16 57.9 2.4 2.7 3 0 0 3 3 3 2 Sugar efflux transporter for intercellular exchange NARP1 PF12569.8 PSC73275.1 - 2.5 6.9 17.8 4.5 6.1 17.8 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 PSC73276.1 - 1.6e-27 93.3 28.1 8e-05 22.5 0.1 11.1 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_7 PF13176.6 PSC73276.1 - 7.6e-21 72.6 20.9 0.01 15.8 0.0 9.7 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.6 PSC73276.1 - 2.1e-19 68.0 2.9 0.0075 16.4 0.0 9.8 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_1 PF00515.28 PSC73276.1 - 2.3e-19 68.3 12.1 1.9e-05 24.3 0.1 8.1 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 PSC73276.1 - 1.2e-17 63.9 59.8 7.1e-07 29.4 0.2 9.8 6 2 3 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 PSC73276.1 - 2.6e-17 63.2 100.0 9.7e-08 32.5 2.4 10.7 7 4 3 10 10 9 6 Tetratricopeptide repeat TPR_19 PF14559.6 PSC73276.1 - 1.1e-15 57.9 52.9 7.3e-06 26.4 1.5 8.8 5 3 7 12 12 11 7 Tetratricopeptide repeat TPR_11 PF13414.6 PSC73276.1 - 3.4e-13 49.0 5.2 6.2e-06 25.8 0.7 5.9 5 1 1 6 6 6 4 TPR repeat TPR_6 PF13174.6 PSC73276.1 - 4.1e-11 42.8 39.1 0.011 16.4 0.1 10.8 12 0 0 12 12 10 4 Tetratricopeptide repeat TPR_14 PF13428.6 PSC73276.1 - 1.8e-09 37.6 80.9 0.0014 19.3 1.6 12.2 5 2 9 14 14 10 6 Tetratricopeptide repeat TPR_17 PF13431.6 PSC73276.1 - 2.2e-06 27.6 18.6 0.19 12.2 0.1 7.8 8 0 0 8 8 8 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PSC73276.1 - 3.1e-06 27.3 14.7 0.063 13.5 2.5 6.0 2 2 3 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 DUF3808 PF10300.9 PSC73276.1 - 0.00051 18.9 0.2 0.003 16.4 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_9 PF13371.6 PSC73276.1 - 0.00077 19.6 3.9 0.00077 19.6 3.9 6.8 6 2 2 8 8 7 4 Tetratricopeptide repeat MIT PF04212.18 PSC73276.1 - 0.001 19.1 2.4 1.6 8.8 0.1 4.7 4 0 0 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 PSC73276.1 - 0.0029 17.4 37.6 0.17 11.8 0.3 9.3 8 1 1 9 9 9 3 Tetratricopeptide repeat Coatomer_E PF04733.14 PSC73276.1 - 0.004 16.6 0.0 1.9 7.8 0.0 3.0 3 0 0 3 3 3 1 Coatomer epsilon subunit RPN7 PF10602.9 PSC73276.1 - 0.059 13.1 3.2 0.7 9.6 0.1 3.6 4 1 0 4 4 4 0 26S proteasome subunit RPN7 NARP1 PF12569.8 PSC73276.1 - 0.15 11.0 0.2 19 4.0 0.0 3.7 3 1 1 4 4 4 0 NMDA receptor-regulated protein 1 TPR_21 PF09976.9 PSC73276.1 - 0.26 11.0 20.8 0.096 12.4 7.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat-like domain SIKE PF05769.11 PSC73277.1 - 0.016 15.1 0.1 0.016 15.1 0.1 1.4 2 0 0 2 2 2 0 SIKE family rve PF00665.26 PSC73278.1 - 2e-18 66.7 0.0 4.5e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Glyco_transf_8 PF01501.20 PSC73278.1 - 1.3e-10 41.3 0.0 0.00098 18.8 0.0 3.1 2 1 0 2 2 2 2 Glycosyl transferase family 8 Methyltransf_12 PF08242.12 PSC73278.1 - 4.5e-06 27.3 0.0 5.5e-05 23.8 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC73278.1 - 0.00014 22.5 0.0 0.0025 18.5 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain rve_3 PF13683.6 PSC73278.1 - 0.016 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Methyltransf_33 PF10017.9 PSC73278.1 - 0.021 14.0 0.0 0.097 11.8 0.0 1.9 2 0 0 2 2 2 0 Histidine-specific methyltransferase, SAM-dependent Methyltransf_31 PF13847.6 PSC73278.1 - 0.031 14.1 0.0 0.092 12.5 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Cytochrome_P460 PF16694.5 PSC73278.1 - 0.098 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Cytochrome P460 TFIIA PF03153.13 PSC73279.1 - 0.64 9.9 17.1 0.83 9.6 17.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MCM PF00493.23 PSC73280.1 - 6.1e-101 336.2 0.0 9.9e-101 335.5 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PSC73280.1 - 1.5e-35 121.7 0.0 3.1e-35 120.8 0.0 1.5 1 0 0 1 1 1 1 MCM OB domain DUF4042 PF13251.6 PSC73280.1 - 2.6e-29 102.2 0.1 1.5e-28 99.7 0.1 2.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4042) MCM_lid PF17855.1 PSC73280.1 - 2e-25 89.0 0.3 6.1e-25 87.5 0.3 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain MCM2_N PF12619.8 PSC73280.1 - 5.9e-14 52.6 16.8 5.9e-14 52.6 16.8 2.2 3 0 0 3 3 2 1 Mini-chromosome maintenance protein 2 MCM_N PF14551.6 PSC73280.1 - 4.6e-13 49.6 0.9 1.1e-12 48.4 0.1 2.1 2 0 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.21 PSC73280.1 - 5.4e-09 35.7 0.0 2.4e-07 30.3 0.0 2.6 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 PSC73280.1 - 5.9e-07 29.6 0.0 1.1e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 PSC73280.1 - 0.00099 18.8 0.1 0.0028 17.4 0.1 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_3 PF07726.11 PSC73280.1 - 0.0043 16.9 0.1 0.025 14.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) HEAT PF02985.22 PSC73280.1 - 0.01 16.1 34.2 0.094 13.0 0.0 8.3 8 0 0 8 8 8 2 HEAT repeat CDV3 PF15359.6 PSC73280.1 - 0.35 11.4 1.8 1.4 9.4 1.8 2.0 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 GST_N_3 PF13417.6 PSC73281.1 - 9e-11 42.0 0.0 1.8e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 PSC73281.1 - 7.3e-09 35.8 0.0 1.2e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PSC73281.1 - 7.7e-07 29.4 0.0 1.4e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 PSC73281.1 - 1.4e-06 28.2 0.3 3.2e-06 27.1 0.3 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PSC73281.1 - 8.5e-05 22.7 0.0 0.00015 21.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_5 PF16865.5 PSC73281.1 - 0.0002 21.9 0.0 0.00033 21.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 PSC73281.1 - 0.0027 17.9 0.0 0.004 17.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Pkinase PF00069.25 PSC73282.1 - 5.6e-74 248.8 0.0 8.8e-74 248.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73282.1 - 4.7e-45 153.9 0.0 7.3e-45 153.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Arm PF00514.23 PSC73282.1 - 1.6e-12 47.0 7.7 4.5e-06 26.5 0.0 6.5 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 PSC73282.1 - 2.6e-12 46.9 2.5 3.1e-07 30.7 0.8 6.3 4 2 2 6 6 5 2 HEAT repeats HEAT PF02985.22 PSC73282.1 - 1.1e-07 31.5 15.2 0.0071 16.5 0.0 5.7 5 0 0 5 5 4 3 HEAT repeat HEAT_EZ PF13513.6 PSC73282.1 - 4.2e-07 30.3 3.0 8.7e-06 26.1 0.2 8.2 8 0 0 8 8 5 3 HEAT-like repeat Kinase-like PF14531.6 PSC73282.1 - 1.4e-06 27.8 0.1 3.8e-06 26.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PSC73282.1 - 0.0002 20.2 2.8 0.00038 19.4 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 PSC73282.1 - 0.00039 19.5 0.0 0.00091 18.3 0.0 1.6 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PSC73282.1 - 0.0074 16.2 0.0 0.0074 16.2 0.0 5.5 5 2 0 5 5 3 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 PSC73282.1 - 0.057 12.9 0.0 0.057 12.9 0.0 1.8 2 0 0 2 2 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 PSC73282.1 - 0.1 11.9 0.1 0.22 10.8 0.1 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 PSC73282.1 - 0.11 11.6 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 RIO1 PF01163.22 PSC73282.1 - 0.14 11.7 0.0 0.26 10.8 0.0 1.3 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 PSC73282.1 - 0.39 10.3 7.0 0.45 10.1 0.0 3.0 2 1 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 FTR1 PF03239.14 PSC73283.1 - 5.5e-45 153.9 16.3 5.5e-45 153.9 16.3 2.2 3 0 0 3 3 3 1 Iron permease FTR1 family MS_channel PF00924.18 PSC73283.1 - 5.4e-15 55.5 0.1 1.4e-14 54.1 0.1 1.7 1 0 0 1 1 1 1 Mechanosensitive ion channel Presenilin PF01080.17 PSC73283.1 - 0.0087 14.9 0.6 0.0087 14.9 0.6 3.4 4 0 0 4 4 4 1 Presenilin DUF3961 PF13106.6 PSC73283.1 - 0.14 11.8 2.8 0.35 10.5 2.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3961) Endostatin PF06482.11 PSC73283.1 - 1.7 8.1 6.0 2.6 7.4 6.0 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF3506 PF12014.8 PSC73284.1 - 2.2e-12 47.2 0.8 1.3e-09 38.1 0.8 3.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) ODR4-like PF14778.6 PSC73285.1 - 1.4e-42 146.0 0.0 1.8e-42 145.6 0.0 1.1 1 0 0 1 1 1 1 Olfactory receptor 4-like DUF826 PF05696.11 PSC73285.1 - 0.33 11.1 3.1 15 5.8 0.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF826) GST_C_2 PF13410.6 PSC73285.1 - 0.7 10.0 5.3 3.1 7.9 1.5 2.5 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain PTH2 PF01981.16 PSC73286.1 - 8.4e-09 35.7 0.9 1.5e-08 34.9 0.2 1.8 2 1 0 2 2 2 1 Peptidyl-tRNA hydrolase PTH2 O-FucT PF10250.9 PSC73287.1 - 2.1e-16 60.6 0.3 3.8e-14 53.1 0.3 2.8 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase DUF2675 PF11247.8 PSC73287.1 - 0.11 12.6 0.0 0.21 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2675) XAP5 PF04921.14 PSC73288.1 - 4.7e-74 249.4 0.1 4.7e-74 249.4 0.1 2.1 1 1 1 2 2 2 1 XAP5, circadian clock regulator GBP_C PF02841.14 PSC73288.1 - 8 5.8 18.6 15 4.9 18.6 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain DUF4647 PF15504.6 PSC73288.1 - 9.1 5.3 10.2 13 4.7 10.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) Methyltransf_11 PF08241.12 PSC73289.1 - 3.5e-11 43.6 0.0 7.8e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC73289.1 - 8.2e-06 26.4 0.0 1.9e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC73289.1 - 2.9e-05 23.9 0.0 4.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC73289.1 - 0.00025 20.9 0.0 0.0004 20.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC73289.1 - 0.0005 20.8 0.0 0.0011 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Zn-ribbon_8 PF09723.10 PSC73289.1 - 0.0047 17.0 0.9 0.89 9.7 0.1 2.6 2 0 0 2 2 2 1 Zinc ribbon domain DZR PF12773.7 PSC73289.1 - 0.034 14.2 0.6 0.07 13.2 0.6 1.4 1 0 0 1 1 1 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 PSC73289.1 - 0.73 9.9 3.3 32 4.6 4.1 2.3 1 1 1 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.6 PSC73289.1 - 1 8.9 3.1 5.6 6.5 0.4 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 PSC73289.1 - 2.7 7.8 4.6 2.3 8.1 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-C3HC4_2 PF13923.6 PSC73290.1 - 8.7e-08 31.9 13.3 1.5e-07 31.1 13.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC73290.1 - 2.4e-07 30.5 10.7 4.1e-07 29.7 10.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC73290.1 - 1.9e-05 24.4 13.8 3.3e-05 23.7 13.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC73290.1 - 1.9e-05 24.5 12.8 3.4e-05 23.7 12.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PSC73290.1 - 7.8e-05 22.5 9.3 0.00013 21.7 9.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PSC73290.1 - 0.0021 18.3 12.9 0.0035 17.7 12.9 1.4 1 0 0 1 1 1 1 Ring finger domain DHR10 PF18595.1 PSC73290.1 - 0.013 15.5 13.0 0.013 15.5 13.0 9.6 4 2 4 9 9 7 0 Designed helical repeat protein 10 domain zf-RING_UBOX PF13445.6 PSC73290.1 - 0.018 15.1 9.5 0.031 14.3 9.5 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 PSC73290.1 - 0.02 15.2 12.1 0.042 14.1 12.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain PKcGMP_CC PF16808.5 PSC73290.1 - 0.033 14.0 0.4 0.033 14.0 0.4 6.1 8 0 0 8 8 7 0 Coiled-coil N-terminus of cGMP-dependent protein kinase zf-RING_4 PF14570.6 PSC73290.1 - 0.18 11.6 7.4 0.35 10.7 7.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 PSC73290.1 - 0.2 11.8 5.8 0.36 10.9 5.8 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.11 PSC73290.1 - 0.24 11.5 3.4 0.68 10.1 3.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.6 PSC73290.1 - 0.79 9.9 9.7 1.2 9.4 8.0 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_5 PF17121.5 PSC73290.1 - 2.2 8.2 7.5 3 7.8 6.4 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 PSC73290.1 - 7.7 6.6 9.3 18 5.5 9.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-C3HC4_2 PF13923.6 PSC73291.1 - 8.7e-08 31.9 13.3 1.5e-07 31.1 13.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC73291.1 - 2.4e-07 30.5 10.7 4.1e-07 29.7 10.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC73291.1 - 1.9e-05 24.4 13.8 3.3e-05 23.7 13.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC73291.1 - 1.9e-05 24.5 12.8 3.4e-05 23.7 12.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PSC73291.1 - 7.8e-05 22.5 9.3 0.00013 21.7 9.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PSC73291.1 - 0.0021 18.3 12.9 0.0035 17.7 12.9 1.4 1 0 0 1 1 1 1 Ring finger domain DHR10 PF18595.1 PSC73291.1 - 0.013 15.5 13.0 0.013 15.5 13.0 9.6 4 2 4 9 9 7 0 Designed helical repeat protein 10 domain zf-RING_UBOX PF13445.6 PSC73291.1 - 0.018 15.1 9.5 0.031 14.3 9.5 1.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.7 PSC73291.1 - 0.02 15.2 12.1 0.042 14.1 12.1 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain PKcGMP_CC PF16808.5 PSC73291.1 - 0.033 14.0 0.4 0.033 14.0 0.4 6.1 8 0 0 8 8 7 0 Coiled-coil N-terminus of cGMP-dependent protein kinase zf-RING_4 PF14570.6 PSC73291.1 - 0.18 11.6 7.4 0.35 10.7 7.4 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 PSC73291.1 - 0.2 11.8 5.8 0.36 10.9 5.8 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.11 PSC73291.1 - 0.24 11.5 3.4 0.68 10.1 3.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.6 PSC73291.1 - 0.79 9.9 9.7 1.2 9.4 8.0 2.0 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-C3HC4_5 PF17121.5 PSC73291.1 - 2.2 8.2 7.5 3 7.8 6.4 1.8 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 PSC73291.1 - 7.7 6.6 9.3 18 5.5 9.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon CHDCT2 PF08074.11 PSC73292.1 - 6.9 6.8 10.4 0.95 9.6 1.0 2.8 3 0 0 3 3 3 0 CHDCT2 (NUC038) domain SET PF00856.28 PSC73293.1 - 2.4e-10 41.0 0.0 4.6e-09 36.9 0.0 2.7 2 2 0 2 2 2 1 SET domain Mannosyl_trans3 PF11051.8 PSC73294.1 - 6.5e-24 84.7 0.0 9.7e-13 48.1 0.0 2.2 1 1 1 2 2 2 2 Mannosyltransferase putative eIF3_subunit PF08597.10 PSC73295.1 - 3.4e-31 109.0 10.2 6.6e-31 108.1 10.2 1.4 1 1 0 1 1 1 1 Translation initiation factor eIF3 subunit ILVD_EDD PF00920.21 PSC73296.1 - 2e-214 713.0 0.1 2.3e-214 712.8 0.1 1.0 1 0 0 1 1 1 1 Dehydratase family Pep3_Vps18 PF05131.14 PSC73297.1 - 4.3e-26 91.5 0.0 7.6e-26 90.7 0.0 1.4 1 0 0 1 1 1 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 PSC73297.1 - 6.2e-06 26.2 0.0 0.074 12.9 0.0 2.6 2 0 0 2 2 2 2 Region in Clathrin and VPS Vps39_2 PF10367.9 PSC73297.1 - 0.037 14.5 0.0 0.089 13.2 0.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 ELYS PF13934.6 PSC73297.1 - 0.11 12.4 1.0 1.1 9.2 0.1 2.7 2 1 0 2 2 2 0 Nuclear pore complex assembly Sec8_exocyst PF04048.14 PSC73297.1 - 0.21 11.5 0.1 0.51 10.2 0.1 1.6 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain MscS_porin PF12795.7 PSC73297.1 - 2.2 7.8 6.5 1.7 8.1 0.1 2.7 3 0 0 3 3 3 0 Mechanosensitive ion channel porin domain 4HBT_3 PF13622.6 PSC73297.1 - 2.9 8.1 6.1 4.2 7.6 0.5 2.7 3 0 0 3 3 3 0 Thioesterase-like superfamily Ribosomal_S17 PF00366.20 PSC73298.1 - 2.3e-24 85.3 3.3 4.2e-24 84.4 3.3 1.5 1 0 0 1 1 1 1 Ribosomal protein S17 zf-MYND PF01753.18 PSC73298.1 - 6.4e-06 26.2 8.7 6.4e-06 26.2 8.7 2.6 2 1 0 2 2 2 1 MYND finger Pox_A_type_inc PF04508.12 PSC73298.1 - 0.045 13.6 0.1 0.14 12.1 0.1 1.8 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat DUF4094 PF13334.6 PSC73298.1 - 1.9 9.0 7.8 0.074 13.5 0.6 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4094) Tic22 PF04278.12 PSC73299.1 - 2.6e-54 184.2 0.5 2e-46 158.4 0.1 2.1 2 0 0 2 2 2 2 Tic22-like family Pex14_N PF04695.13 PSC73299.1 - 0.00046 20.9 1.4 0.00097 19.8 1.4 1.5 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Inhibitor_I69 PF13734.6 PSC73299.1 - 0.0022 18.4 0.0 0.0022 18.4 0.0 2.9 3 1 0 3 3 3 1 Spi protease inhibitor Golgin_A5 PF09787.9 PSC73299.1 - 0.13 11.7 6.5 0.17 11.3 5.3 1.7 2 0 0 2 2 2 0 Golgin subfamily A member 5 Lipase_GDSL_2 PF13472.6 PSC73299.1 - 0.18 12.2 6.1 2.3 8.6 2.2 3.2 1 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family DUF2203 PF09969.9 PSC73299.1 - 0.74 10.5 7.4 15 6.3 3.8 2.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) SF3b10 PF07189.11 PSC73300.1 - 1.3e-33 114.9 0.0 1.5e-33 114.7 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) zf-4CXXC_R1 PF10497.9 PSC73301.1 - 7.3e-37 125.6 10.2 1.4e-36 124.7 10.2 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 O-FucT PF10250.9 PSC73302.1 - 1e-11 45.2 0.1 4.4e-10 39.8 0.0 2.9 2 1 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase Glyco_transf_8 PF01501.20 PSC73302.1 - 0.21 11.1 3.0 3.2 7.2 1.7 2.6 2 0 0 2 2 2 0 Glycosyl transferase family 8 DNA_pol_B PF00136.21 PSC73303.1 - 2e-121 405.9 0.0 6e-121 404.3 0.0 1.7 1 1 0 1 1 1 1 DNA polymerase family B GCP_C_terminal PF04130.13 PSC73303.1 - 9.8e-38 130.3 0.0 1.7e-37 129.6 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 PSC73303.1 - 1.1e-32 113.9 0.0 5e-32 111.8 0.0 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal zf-DNA_Pol PF08996.10 PSC73303.1 - 3.1e-29 102.0 0.0 5.7e-29 101.2 0.0 1.5 1 0 0 1 1 1 1 DNA Polymerase alpha zinc finger DNA_pol_B_exo1 PF03104.19 PSC73303.1 - 1.3e-27 96.9 0.0 2.7e-27 95.8 0.0 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_alpha_N PF12254.8 PSC73303.1 - 7.8e-18 64.3 3.7 1.8e-17 63.2 3.7 1.6 1 0 0 1 1 1 1 DNA polymerase alpha subunit p180 N terminal DNA_pol_B_2 PF03175.13 PSC73303.1 - 0.049 12.5 0.0 0.1 11.4 0.0 1.4 1 0 0 1 1 1 0 DNA polymerase type B, organellar and viral DUF1744 PF08490.12 PSC73303.1 - 0.19 10.3 0.0 0.28 9.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1744) Mannosyl_trans3 PF11051.8 PSC73304.1 - 8.3e-21 74.6 0.0 4.5e-18 65.6 0.0 2.2 2 0 0 2 2 2 2 Mannosyltransferase putative U-box PF04564.15 PSC73305.1 - 1.3e-12 47.7 0.0 2.9e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 PSC73305.1 - 3.9e-06 26.6 0.0 7.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 PSC73305.1 - 0.0031 17.5 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 PSC73305.1 - 0.016 15.3 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Nas2_N PF18265.1 PSC73305.1 - 0.17 11.9 0.0 0.84 9.6 0.0 1.9 2 0 0 2 2 2 0 Nas2 N_terminal domain U-box PF04564.15 PSC73306.1 - 1.3e-12 47.7 0.0 2.9e-12 46.6 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 PSC73306.1 - 3.9e-06 26.6 0.0 7.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 PSC73306.1 - 0.0031 17.5 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-NOSIP PF15906.5 PSC73306.1 - 0.016 15.3 0.0 0.029 14.5 0.0 1.4 1 0 0 1 1 1 0 Zinc-finger of nitric oxide synthase-interacting protein Nas2_N PF18265.1 PSC73306.1 - 0.17 11.9 0.0 0.84 9.6 0.0 1.9 2 0 0 2 2 2 0 Nas2 N_terminal domain Pkinase PF00069.25 PSC73307.1 - 7.4e-26 91.1 0.0 9.7e-26 90.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73307.1 - 1.9e-14 53.5 0.0 2.8e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PSC73307.1 - 1.6e-09 37.1 0.1 2.2e-09 36.6 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF1674 PF07896.12 PSC73307.1 - 1.5e-08 35.0 9.9 7e-08 32.8 9.9 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) APH PF01636.23 PSC73307.1 - 0.00018 21.5 0.4 0.0012 18.9 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family SBDS_C PF09377.10 PSC73308.1 - 2e-30 105.2 0.0 3.8e-30 104.3 0.0 1.4 1 0 0 1 1 1 1 SBDS protein C-terminal domain SBDS PF01172.18 PSC73308.1 - 2.4e-30 104.4 0.4 3.6e-30 103.9 0.4 1.3 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein MBD PF01429.19 PSC73308.1 - 0.0016 18.1 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 Methyl-CpG binding domain UCH PF00443.29 PSC73309.1 - 3.4e-54 184.0 0.4 5.5e-54 183.4 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_S13 PF00416.22 PSC73309.1 - 6e-28 97.8 1.8 6e-28 97.8 1.8 2.5 2 1 0 2 2 2 1 Ribosomal protein S13/S18 UCH_1 PF13423.6 PSC73309.1 - 3.2e-19 69.7 0.0 1.1e-18 68.0 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase LRRNT_2 PF08263.12 PSC73309.1 - 0.018 15.3 0.3 0.044 14.1 0.3 1.6 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain FbpA PF05833.11 PSC73309.1 - 0.34 9.6 0.0 0.34 9.6 0.0 2.6 3 0 0 3 3 3 0 Fibronectin-binding protein A N-terminus (FbpA) YabA PF06156.13 PSC73309.1 - 4.3 8.0 8.7 16 6.2 8.7 2.0 1 0 0 1 1 1 0 Initiation control protein YabA UCH PF00443.29 PSC73310.1 - 3.4e-54 184.0 0.4 5.5e-54 183.4 0.0 1.6 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Ribosomal_S13 PF00416.22 PSC73310.1 - 6e-28 97.8 1.8 6e-28 97.8 1.8 2.5 2 1 0 2 2 2 1 Ribosomal protein S13/S18 UCH_1 PF13423.6 PSC73310.1 - 3.2e-19 69.7 0.0 1.1e-18 68.0 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase LRRNT_2 PF08263.12 PSC73310.1 - 0.018 15.3 0.3 0.044 14.1 0.3 1.6 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain FbpA PF05833.11 PSC73310.1 - 0.34 9.6 0.0 0.34 9.6 0.0 2.6 3 0 0 3 3 3 0 Fibronectin-binding protein A N-terminus (FbpA) YabA PF06156.13 PSC73310.1 - 4.3 8.0 8.7 16 6.2 8.7 2.0 1 0 0 1 1 1 0 Initiation control protein YabA TPT PF03151.16 PSC73311.1 - 4.2e-11 42.7 12.4 5.3e-11 42.4 12.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PSC73311.1 - 1.6e-07 31.6 25.7 0.00021 21.4 9.7 2.4 2 1 0 2 2 2 2 EamA-like transporter family DUF2070 PF09843.9 PSC73311.1 - 6.4 4.9 17.2 0.018 13.3 6.4 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2070) Glyco_transf_5 PF08323.11 PSC73312.1 - 6.5e-19 68.6 0.0 2.2e-10 40.7 0.0 3.0 2 1 0 2 2 2 2 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 PSC73312.1 - 1.7e-07 30.9 0.0 0.0036 16.9 0.0 2.3 2 0 0 2 2 2 2 Glycosyl transferases group 1 FixQ PF05545.11 PSC73313.1 - 0.0023 17.9 1.2 0.0039 17.1 1.2 1.4 1 0 0 1 1 1 1 Cbb3-type cytochrome oxidase component FixQ SWIM PF04434.17 PSC73313.1 - 0.008 15.8 0.6 0.016 14.9 0.6 1.5 1 0 0 1 1 1 1 SWIM zinc finger BatD PF13584.6 PSC73313.1 - 0.019 13.8 0.1 0.026 13.3 0.1 1.1 1 0 0 1 1 1 0 Oxygen tolerance PepSY_TM PF03929.16 PSC73313.1 - 0.064 12.9 5.9 0.049 13.3 4.1 1.5 1 1 0 2 2 2 0 PepSY-associated TM region HLH PF00010.26 PSC73314.1 - 1.6e-08 34.4 0.6 3.4e-08 33.3 0.6 1.6 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Tom22 PF04281.13 PSC73314.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 S-methyl_trans PF02574.16 PSC73315.1 - 3.1e-154 512.5 1.8 6.2e-76 255.7 0.1 2.6 2 0 0 2 2 2 2 Homocysteine S-methyltransferase Met_synt_B12 PF02965.17 PSC73315.1 - 1.5e-115 385.3 0.2 3.8e-115 384.1 0.0 1.8 3 0 0 3 3 3 1 Vitamin B12 dependent methionine synthase, activation domain Pterin_bind PF00809.22 PSC73315.1 - 4.1e-109 364.0 0.7 4.7e-53 180.4 0.0 3.4 3 0 0 3 3 3 2 Pterin binding enzyme B12-binding_2 PF02607.17 PSC73315.1 - 3.4e-23 81.9 2.1 5.9e-22 77.9 0.0 3.9 3 0 0 3 3 3 1 B12 binding domain B12-binding PF02310.19 PSC73315.1 - 4.7e-17 62.1 3.6 1.9e-16 60.2 0.3 3.6 4 0 0 4 4 4 1 B12 binding domain RNase_J_C PF17770.1 PSC73315.1 - 0.0019 19.2 0.0 19 6.4 0.0 4.1 3 0 0 3 3 3 0 Ribonuclease J C-terminal domain YqaH PF17448.2 PSC73315.1 - 0.0025 18.1 0.5 5.6 7.3 0.1 3.1 2 0 0 2 2 2 2 Uncharacterized YqaH-like OKR_DC_1_C PF03711.15 PSC73315.1 - 0.013 15.8 0.0 11 6.3 0.0 2.7 2 0 0 2 2 2 0 Orn/Lys/Arg decarboxylase, C-terminal domain FtsK_SpoIIIE PF01580.18 PSC73315.1 - 0.067 12.5 0.0 3 7.1 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF1589 PF07628.11 PSC73315.1 - 0.088 12.9 0.0 24 5.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1589) Aminotran_1_2 PF00155.21 PSC73315.1 - 0.11 11.6 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class I and II Polo_box_3 PF18544.1 PSC73315.1 - 0.14 12.8 0.6 50 4.6 0.0 3.2 3 0 0 3 3 3 0 Polo box domain DUF2709 PF10915.8 PSC73315.1 - 0.16 11.2 0.0 22 4.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2709) TPR_6 PF13174.6 PSC73315.1 - 1 10.2 7.7 29 5.6 0.3 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat YgbA_NO PF11756.8 PSC73315.1 - 2 8.8 4.5 69 3.9 0.1 3.7 4 0 0 4 4 4 0 Nitrous oxide-stimulated promoter OrfB_IS605 PF01385.19 PSC73316.1 - 0.7 10.1 5.1 2.6 8.3 0.2 3.2 2 1 1 3 3 3 0 Probable transposase ApoLp-III PF07464.11 PSC73316.1 - 1.1 9.4 10.2 0.14 12.3 3.4 2.9 2 1 0 3 3 3 0 Apolipophorin-III precursor (apoLp-III) ThiF PF00899.21 PSC73317.1 - 6e-50 169.9 0.1 9.9e-50 169.2 0.1 1.3 1 0 0 1 1 1 1 ThiF family ApoL PF05461.11 PSC73317.1 - 0.0019 17.6 1.1 0.0043 16.4 1.1 1.5 1 0 0 1 1 1 1 Apolipoprotein L 2-Hacid_dh_C PF02826.19 PSC73317.1 - 0.002 17.5 0.0 0.0044 16.4 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 PSC73317.1 - 0.053 13.8 0.0 16 5.7 0.0 3.2 3 0 0 3 3 3 0 TrkA-N domain HsbA PF12296.8 PSC73317.1 - 0.08 13.4 1.8 0.24 11.8 1.2 2.1 2 0 0 2 2 2 0 Hydrophobic surface binding protein A NAD_binding_7 PF13241.6 PSC73317.1 - 0.097 13.1 0.0 0.33 11.4 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding HALZ PF02183.18 PSC73317.1 - 0.25 11.6 1.4 1.2 9.4 1.4 2.2 1 0 0 1 1 1 0 Homeobox associated leucine zipper GIT_CC PF16559.5 PSC73317.1 - 0.87 9.5 5.2 0.35 10.8 0.9 2.4 1 1 1 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor Cpn60_TCP1 PF00118.24 PSC73318.1 - 2.3e-168 560.9 1.8 2.8e-168 560.5 1.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family tRNA-synt_2b PF00587.25 PSC73319.1 - 1.6e-37 129.2 0.0 2.9e-37 128.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 PSC73319.1 - 1.6e-22 79.4 4.7 8.2e-21 74.0 1.6 2.5 2 0 0 2 2 2 2 Anticodon binding domain TGS PF02824.21 PSC73319.1 - 2.2e-12 46.8 0.0 5.3e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.14 PSC73319.1 - 2e-06 27.8 0.0 4e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Leu_Phe_trans PF03588.14 PSC73319.1 - 0.058 12.9 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Leucyl/phenylalanyl-tRNA protein transferase DUF3692 PF12469.8 PSC73319.1 - 0.066 13.4 0.0 0.36 11.0 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein CRAL_TRIO PF00650.20 PSC73320.1 - 5.4e-22 78.2 0.0 1.4e-21 76.9 0.0 1.7 1 0 0 1 1 1 1 CRAL/TRIO domain RWP-RK PF02042.15 PSC73320.1 - 7.5e-17 61.0 0.0 1.7e-16 59.9 0.0 1.7 1 0 0 1 1 1 1 RWP-RK domain CRAL_TRIO_2 PF13716.6 PSC73320.1 - 0.16 12.1 0.0 0.64 10.2 0.0 1.9 1 1 0 1 1 1 0 Divergent CRAL/TRIO domain CDC14 PF08045.11 PSC73321.1 - 0.0026 16.9 0.0 0.0038 16.4 0.0 1.1 1 0 0 1 1 1 1 Cell division control protein 14, SIN component Arm PF00514.23 PSC73321.1 - 0.026 14.6 1.9 2.9 8.0 1.1 2.7 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat CBM_20 PF00686.19 PSC73322.1 - 6.3e-23 80.5 0.1 1e-22 79.8 0.1 1.3 1 0 0 1 1 1 1 Starch binding domain CBM53 PF16760.5 PSC73322.1 - 0.12 13.0 0.1 0.25 12.0 0.1 1.5 1 0 0 1 1 1 0 Starch/carbohydrate-binding module (family 53) AMPK1_CBM PF16561.5 PSC73322.1 - 0.13 12.4 0.0 0.24 11.6 0.0 1.3 1 0 0 1 1 1 0 Glycogen recognition site of AMP-activated protein kinase Phosphorylase PF00343.20 PSC73324.1 - 0 1039.5 0.0 0 1038.9 0.0 1.3 1 0 0 1 1 1 1 Carbohydrate phosphorylase Porin_3 PF01459.22 PSC73324.1 - 4.9e-64 216.4 0.0 8e-64 215.7 0.0 1.3 1 0 0 1 1 1 1 Eukaryotic porin ACT PF01842.25 PSC73324.1 - 0.00011 21.9 0.0 0.00026 20.7 0.0 1.6 1 0 0 1 1 1 1 ACT domain MDM10 PF12519.8 PSC73324.1 - 0.0011 18.0 0.1 0.0017 17.3 0.1 1.2 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 Tegument_dsDNA PF12818.7 PSC73325.1 - 0.047 12.8 0.2 0.067 12.3 0.2 1.2 1 0 0 1 1 1 0 dsDNA viral tegument protein Tegument_dsDNA PF12818.7 PSC73326.1 - 0.051 12.7 0.2 0.076 12.1 0.2 1.2 1 0 0 1 1 1 0 dsDNA viral tegument protein Aldose_epim PF01263.20 PSC73327.1 - 1.8e-46 158.8 0.0 2.1e-46 158.6 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase Fcf2 PF08698.11 PSC73328.1 - 3e-35 120.5 0.1 6.5e-35 119.4 0.1 1.6 1 0 0 1 1 1 1 Fcf2 pre-rRNA processing WD40 PF00400.32 PSC73329.1 - 1e-09 38.9 0.3 0.00098 19.9 0.3 3.2 2 0 0 2 2 2 2 WD domain, G-beta repeat Ge1_WD40 PF16529.5 PSC73329.1 - 6.9e-07 28.5 0.0 0.0042 16.1 0.0 3.2 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein ANAPC4_WD40 PF12894.7 PSC73329.1 - 0.07 13.4 0.0 0.39 11.0 0.0 2.4 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain CPDase PF07823.11 PSC73329.1 - 0.19 11.4 0.3 0.79 9.4 0.0 1.9 2 0 0 2 2 2 0 Cyclic phosphodiesterase-like protein Band_7 PF01145.25 PSC73330.1 - 7.3e-31 107.5 1.0 1.9e-30 106.2 1.0 1.7 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_C PF16200.5 PSC73330.1 - 5.4e-26 90.4 0.4 1.4e-25 89.1 0.4 1.8 1 0 0 1 1 1 1 C-terminal region of band_7 rve PF00665.26 PSC73330.1 - 9.6e-19 67.7 0.0 3.3e-18 66.0 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 PSC73330.1 - 0.011 15.5 0.0 0.032 14.0 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain tRNA_synthFbeta PF17759.1 PSC73331.1 - 4.3e-44 150.5 0.0 6.8e-44 149.9 0.0 1.3 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 PSC73331.1 - 5.9e-34 116.2 0.1 1.4e-33 115.0 0.1 1.7 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 PSC73331.1 - 3.8e-26 91.8 0.0 5.8e-26 91.2 0.0 1.3 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 PSC73331.1 - 5.2e-18 65.1 0.0 5.7e-16 58.6 0.0 2.6 2 0 0 2 2 2 1 tRNA synthetase B5 domain BAH PF01426.18 PSC73332.1 - 5.8e-09 35.9 0.0 8.7e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 BAH domain PHD PF00628.29 PSC73332.1 - 0.001 18.9 3.2 0.0015 18.4 2.2 1.8 2 0 0 2 2 2 1 PHD-finger TFIIA PF03153.13 PSC73332.1 - 0.089 12.8 16.7 0.11 12.5 16.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 PSC73332.1 - 0.63 8.7 27.0 0.8 8.3 27.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal EIF4E-T PF10477.9 PSC73332.1 - 1.6 7.5 10.2 1.9 7.2 10.2 1.1 1 0 0 1 1 1 0 Nucleocytoplasmic shuttling protein for mRNA cap-binding EIF4E Spt20 PF12090.8 PSC73332.1 - 4.6 6.8 18.0 6.8 6.2 18.0 1.2 1 0 0 1 1 1 0 Spt20 family HORMA PF02301.18 PSC73333.1 - 1.9e-23 83.2 0.0 4.1e-23 82.1 0.0 1.5 1 1 0 1 1 1 1 HORMA domain ATG101 PF07855.12 PSC73333.1 - 0.0023 18.0 0.0 0.015 15.3 0.0 2.0 1 1 0 1 1 1 1 Autophagy-related protein 101 bacHORMA_2 PF18173.1 PSC73333.1 - 0.0026 17.6 0.1 0.0058 16.5 0.0 1.6 2 0 0 2 2 2 1 Bacterial HORMA domain 2 Neur_chan_LBD PF02931.23 PSC73333.1 - 0.035 13.6 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel ligand binding domain DUF4147 PF13660.6 PSC73333.1 - 0.13 11.8 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4147) Aldolase_II PF00596.21 PSC73334.1 - 2.5e-40 138.4 0.0 4.6e-40 137.5 0.0 1.4 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Hydrolase PF00702.26 PSC73334.1 - 2.3e-05 24.8 0.3 4.1e-05 24.0 0.3 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase M16C_assoc PF08367.11 PSC73335.1 - 2.7e-71 239.6 0.0 4.1e-71 239.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 PSC73335.1 - 3.4e-26 92.4 0.0 8.8e-22 78.0 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 PSC73335.1 - 8.4e-06 25.8 0.0 2.4e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Methyltransf_21 PF05050.12 PSC73335.1 - 2.1e-05 24.6 0.0 5.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase FkbM domain Methyltransf_22 PF13383.6 PSC73335.1 - 0.00053 19.6 0.2 0.0018 17.9 0.2 1.8 2 0 0 2 2 2 1 Methyltransferase domain Cpn10 PF00166.21 PSC73336.1 - 1.5e-44 150.0 0.0 7.6e-21 74.0 0.0 4.4 4 0 0 4 4 4 4 Chaperonin 10 Kd subunit FPN1 PF06963.12 PSC73336.1 - 1.5e-38 132.5 3.3 2.1e-16 59.5 0.2 3.2 3 0 0 3 3 3 3 Ferroportin1 (FPN1) Hydrolase_6 PF13344.6 PSC73336.1 - 2.8e-22 78.7 0.0 5.9e-22 77.7 0.0 1.6 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Cu-oxidase_2 PF07731.14 PSC73336.1 - 2.9e-11 43.3 0.1 5.8e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 Multicopper oxidase Hydrolase_like PF13242.6 PSC73336.1 - 2.2e-09 37.2 0.1 6.6e-09 35.7 0.1 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like LRR_8 PF13855.6 PSC73336.1 - 7.4e-08 32.0 1.0 0.0011 18.7 0.3 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PSC73336.1 - 3.7e-06 27.2 3.8 0.00025 21.4 0.9 3.5 2 1 0 3 3 2 1 Leucine Rich repeats (2 copies) Toxin_GhoT_OrtT PF10753.9 PSC73336.1 - 5.9e-06 26.4 0.9 4.9 7.5 0.0 3.7 4 0 0 4 4 3 3 Toxin GhoT_OrtT Cu-oxidase_3 PF07732.15 PSC73336.1 - 0.0001 22.3 0.1 0.75 9.8 0.0 2.5 2 0 0 2 2 2 2 Multicopper oxidase F-box-like PF12937.7 PSC73336.1 - 0.001 18.9 0.8 0.0041 17.0 0.8 2.2 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.33 PSC73336.1 - 0.079 13.6 2.2 1.9 9.3 0.3 3.9 4 0 0 4 4 4 0 Leucine Rich Repeat Cu-oxidase PF00394.22 PSC73336.1 - 0.12 12.5 0.0 0.32 11.1 0.0 1.7 1 0 0 1 1 1 0 Multicopper oxidase LRR_6 PF13516.6 PSC73336.1 - 0.18 11.9 1.3 4 7.8 0.4 3.4 4 0 0 4 4 3 0 Leucine Rich repeat MMR_HSR1 PF01926.23 PSC73338.1 - 0.16 12.0 0.0 0.28 11.3 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase zf-RING_2 PF13639.6 PSC73339.1 - 2.2e-13 50.3 6.8 3.2e-13 49.8 6.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 PSC73339.1 - 2.1e-11 43.3 1.0 3.8e-11 42.5 1.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 PSC73339.1 - 1.9e-09 37.2 5.2 2.8e-09 36.7 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PA PF02225.22 PSC73339.1 - 2.3e-09 37.2 0.0 7.3e-09 35.5 0.0 1.9 1 0 0 1 1 1 1 PA domain zf-C3HC4 PF00097.25 PSC73339.1 - 4.3e-09 36.1 3.8 6.2e-09 35.6 3.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC73339.1 - 4.2e-07 29.8 3.5 6.1e-07 29.3 3.5 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PSC73339.1 - 7.6e-07 29.1 1.7 4.5e-06 26.6 1.9 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 PSC73339.1 - 4.1e-06 27.0 8.3 1.4e-05 25.3 8.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 PSC73339.1 - 9.9e-05 22.1 5.1 0.00015 21.5 5.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PSC73339.1 - 0.0017 18.2 6.0 0.0027 17.5 6.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 PSC73339.1 - 0.0029 17.2 5.3 0.0053 16.4 5.3 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type HPP PF04982.13 PSC73339.1 - 0.01 16.0 0.5 0.037 14.2 0.5 2.0 1 0 0 1 1 1 0 HPP family zf-RING_4 PF14570.6 PSC73339.1 - 0.016 15.0 5.0 0.026 14.3 5.0 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 PSC73339.1 - 0.038 14.0 5.0 0.097 12.7 5.0 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zinc_ribbon_16 PF17034.5 PSC73339.1 - 0.27 11.5 2.6 0.62 10.3 2.6 1.5 1 0 0 1 1 1 0 Zinc-ribbon like family zf-RING-like PF08746.11 PSC73339.1 - 0.28 11.5 5.1 0.48 10.8 5.1 1.4 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 PSC73339.1 - 0.5 10.5 5.0 1.2 9.3 5.0 1.7 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.29 PSC73339.1 - 0.79 9.7 5.2 1.4 8.9 5.2 1.4 1 0 0 1 1 1 0 PHD-finger FANCL_C PF11793.8 PSC73339.1 - 2.3 8.4 5.3 6.1 7.1 5.3 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain SBP PF03110.14 PSC73340.1 - 3.2e-28 97.8 13.8 5.6e-28 97.1 13.8 1.4 1 0 0 1 1 1 1 SBP domain Ank_2 PF12796.7 PSC73340.1 - 0.0026 18.3 0.5 0.079 13.6 0.1 2.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC73340.1 - 0.018 15.6 0.2 0.17 12.5 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC73340.1 - 0.03 14.7 5.1 4.9 7.6 0.1 3.5 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC73340.1 - 0.056 14.0 1.0 40 5.2 0.2 3.7 3 0 0 3 3 3 0 Ankyrin repeat Fer4_5 PF12801.7 PSC73341.1 - 9.1e-08 31.9 6.1 9.1e-08 31.9 6.1 2.7 3 0 0 3 3 3 1 4Fe-4S binding domain Fer4_6 PF12837.7 PSC73341.1 - 0.0048 16.9 2.4 0.0048 16.9 2.4 2.3 2 0 0 2 2 2 1 4Fe-4S binding domain Fer4 PF00037.27 PSC73341.1 - 0.026 14.3 1.1 0.026 14.3 1.1 2.1 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.6 PSC73341.1 - 0.039 14.1 0.4 0.039 14.1 0.4 2.1 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 PSC73341.1 - 0.96 10.1 6.3 0.38 11.4 2.7 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 PSC73341.1 - 3.3 8.3 13.1 0.15 12.6 7.1 1.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain Wtap PF17098.5 PSC73342.1 - 8.3e-24 84.3 9.4 1.3e-23 83.6 9.4 1.3 1 0 0 1 1 1 1 WTAP/Mum2p family 2OG-FeII_Oxy_3 PF13640.6 PSC73342.1 - 1.1e-14 55.1 0.0 2.6e-14 53.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 PSC73342.1 - 0.036 14.3 0.3 0.38 11.0 0.0 2.4 2 1 0 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) HIP1_clath_bdg PF16515.5 PSC73342.1 - 0.047 14.3 0.2 0.047 14.3 0.2 3.4 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 AIP3 PF03915.13 PSC73342.1 - 0.43 9.6 2.5 0.6 9.1 2.5 1.1 1 0 0 1 1 1 0 Actin interacting protein 3 SKA2 PF16740.5 PSC73342.1 - 0.71 9.7 7.4 0.13 12.0 2.2 2.2 2 1 0 2 2 2 0 Spindle and kinetochore-associated protein 2 GAS PF13851.6 PSC73342.1 - 0.74 9.1 7.3 0.5 9.7 3.4 2.1 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 PSC73342.1 - 3.5 6.4 11.0 6.3 5.6 7.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein ATG16 PF08614.11 PSC73342.1 - 3.6 7.8 23.2 5.1 7.3 6.9 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Cep57_CLD_2 PF14197.6 PSC73342.1 - 4.3 7.5 12.4 1.4 9.1 6.6 3.0 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 CENP-F_leu_zip PF10473.9 PSC73342.1 - 9.2 6.3 9.2 0.79 9.7 2.6 2.5 3 0 0 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4763 PF15960.5 PSC73343.1 - 0.01 15.2 1.7 0.01 15.2 1.7 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4763) C2-C2_1 PF11618.8 PSC73343.1 - 0.052 13.6 0.1 0.19 11.8 0.0 2.0 2 1 0 2 2 2 0 First C2 domain of RPGR-interacting protein 1 UPF0242 PF06785.11 PSC73343.1 - 0.18 11.9 18.5 0.46 10.6 0.5 4.1 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus ATG16 PF08614.11 PSC73343.1 - 1.2 9.3 37.7 1 9.6 0.5 4.7 4 1 0 4 4 4 0 Autophagy protein 16 (ATG16) RPN2_C PF18004.1 PSC73344.1 - 6.8e-41 139.8 1.3 6.8e-41 139.8 1.3 1.8 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 PSC73344.1 - 5.2e-32 108.7 26.5 1.7e-06 28.2 0.0 8.0 8 0 0 8 8 8 6 Proteasome/cyclosome repeat HEAT_2 PF13646.6 PSC73344.1 - 6.5e-18 64.9 7.7 2.7e-12 46.9 0.0 5.0 5 1 2 7 7 7 4 HEAT repeats HEAT_EZ PF13513.6 PSC73344.1 - 1.7e-05 25.2 2.0 0.0099 16.4 0.1 4.0 2 1 1 3 3 3 2 HEAT-like repeat HEAT PF02985.22 PSC73344.1 - 0.048 13.9 0.3 5 7.7 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat Clathrin_H_link PF13838.6 PSC73344.1 - 0.12 12.3 0.0 0.4 10.6 0.0 1.8 1 0 0 1 1 1 0 Clathrin-H-link TPR_2 PF07719.17 PSC73346.1 - 1.1e-33 112.6 22.0 0.00015 21.6 0.1 10.0 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_1 PF00515.28 PSC73346.1 - 4.8e-31 105.3 5.9 1.1e-06 28.1 0.0 8.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 PSC73346.1 - 1.8e-24 83.8 0.0 0.00014 21.8 0.0 7.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_11 PF13414.6 PSC73346.1 - 2.4e-20 71.9 3.7 1.8e-07 30.7 0.0 6.8 4 3 3 7 7 7 4 TPR repeat TPR_7 PF13176.6 PSC73346.1 - 3.3e-19 67.4 2.6 1.5e-05 24.7 0.0 6.5 6 0 0 6 6 5 3 Tetratricopeptide repeat ANAPC3 PF12895.7 PSC73346.1 - 1.4e-17 63.7 21.2 3.4e-16 59.2 2.6 5.9 4 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 Peptidase_M11 PF05548.11 PSC73346.1 - 2.9e-16 59.5 2.7 4.8e-16 58.8 2.7 1.2 1 0 0 1 1 1 1 Gametolysin peptidase M11 TPR_14 PF13428.6 PSC73346.1 - 1.4e-15 56.6 33.5 0.045 14.6 0.2 10.9 6 3 5 11 11 11 6 Tetratricopeptide repeat TPR_12 PF13424.6 PSC73346.1 - 8.9e-14 51.5 25.9 8.2e-08 32.4 0.3 7.3 6 1 0 7 7 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 PSC73346.1 - 6.3e-12 46.0 26.7 2.1e-05 25.1 0.0 6.2 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 PSC73346.1 - 2.4e-11 43.2 1.8 0.32 11.5 0.0 7.1 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 PSC73346.1 - 2e-09 37.8 9.0 0.8 10.3 0.1 6.8 3 1 2 7 7 7 3 Tetratricopeptide repeat TPR_10 PF13374.6 PSC73346.1 - 6.6e-09 35.4 11.2 0.04 13.8 0.1 6.7 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_9 PF13371.6 PSC73346.1 - 3.6e-05 23.8 13.6 0.02 15.0 0.1 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_3 PF07720.12 PSC73346.1 - 0.0018 18.2 4.0 0.0077 16.2 0.2 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.6 PSC73346.1 - 0.0037 17.8 7.5 20 6.1 0.0 6.6 6 0 0 6 6 5 0 Tetratricopeptide repeat ANAPC8 PF04049.13 PSC73346.1 - 0.038 14.0 6.5 0.18 11.8 2.3 3.4 2 1 0 2 2 1 0 Anaphase promoting complex subunit 8 / Cdc23 Sel1 PF08238.12 PSC73346.1 - 0.15 12.8 7.9 5.1 7.9 0.0 4.9 4 0 0 4 4 3 0 Sel1 repeat Spt20 PF12090.8 PSC73346.1 - 1.4 8.5 7.1 2.1 7.9 7.1 1.2 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 PSC73346.1 - 3.4 7.6 8.3 5.3 6.9 8.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4810 PF16068.5 PSC73346.1 - 9.6 6.8 7.0 16 6.1 0.0 3.7 5 0 0 5 5 3 0 Domain of unknown function (DUF4810) Med10 PF09748.9 PSC73347.1 - 4.6e-14 52.4 0.2 7.1e-14 51.8 0.2 1.2 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex TPT PF03151.16 PSC73348.1 - 3.3e-18 66.1 13.3 4.3e-18 65.7 13.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family PRA1 PF03208.19 PSC73348.1 - 5.5e-11 42.3 0.0 5.5e-11 42.3 0.0 4.2 2 1 2 4 4 4 1 PRA1 family protein EamA PF00892.20 PSC73348.1 - 3e-10 40.4 25.5 1.8e-07 31.4 7.4 3.1 3 0 0 3 3 3 2 EamA-like transporter family UAA PF08449.11 PSC73348.1 - 2.6e-06 26.9 9.0 7.6e-05 22.1 9.0 2.3 1 1 0 1 1 1 1 UAA transporter family LCM PF04072.14 PSC73349.1 - 1.6e-26 93.4 0.1 7.6e-25 87.9 0.1 2.4 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Neisseria_TspB PF05616.13 PSC73349.1 - 0.14 10.6 1.7 0.19 10.2 1.7 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein CCDC53 PF10152.9 PSC73349.1 - 6.3 7.2 5.4 12 6.3 5.4 1.4 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex GAF_2 PF13185.6 PSC73350.1 - 7.6e-09 36.0 0.0 1.9e-08 34.7 0.0 1.7 1 0 0 1 1 1 1 GAF domain GAF PF01590.26 PSC73350.1 - 7.1e-05 23.5 0.0 0.00015 22.4 0.0 1.5 1 0 0 1 1 1 1 GAF domain GAF_3 PF13492.6 PSC73350.1 - 0.0036 17.6 0.0 0.0087 16.4 0.0 1.6 1 0 0 1 1 1 1 GAF domain ThiF PF00899.21 PSC73352.1 - 1.2e-67 227.9 0.0 1.6e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 PSC73352.1 - 1.4e-20 73.2 0.0 2.2e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain UAE_UbL PF14732.6 PSC73352.1 - 0.012 16.2 0.0 0.024 15.2 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 PSC73352.1 - 0.1 12.7 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase E1_UFD PF09358.10 PSC73352.1 - 0.14 12.9 0.0 0.91 10.3 0.0 2.1 2 0 0 2 2 2 0 Ubiquitin fold domain Tic110 PF16940.5 PSC73353.1 - 2.5e-201 670.1 22.9 5.9e-198 659.0 12.9 3.4 2 1 0 3 3 3 3 Chloroplast envelope transporter DUF4746 PF15928.5 PSC73353.1 - 0.78 9.1 10.6 1.5 8.2 10.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SRP-alpha_N PF04086.13 PSC73353.1 - 2.2 8.2 16.8 5.1 6.9 16.8 1.5 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RCC1 PF00415.18 PSC73354.1 - 8.6e-64 212.0 18.3 6.5e-13 49.1 0.1 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PSC73354.1 - 1.8e-32 110.4 42.4 1.2e-08 34.5 0.3 8.7 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat Herpes_capsid PF06112.11 PSC73354.1 - 0.26 11.3 16.8 0.67 10.0 16.8 1.6 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Complex1_LYR PF05347.15 PSC73355.1 - 2.9e-12 46.4 0.2 3.4e-12 46.2 0.2 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 PSC73355.1 - 0.00016 22.2 0.1 0.00017 22.1 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 PSC73355.1 - 0.0027 18.4 0.0 0.0031 18.2 0.0 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Trypsin_2 PF13365.6 PSC73356.1 - 5.3e-34 118.3 1.3 1e-33 117.3 1.3 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 PSC73356.1 - 5.3e-16 59.1 0.1 8.6e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 PSC73356.1 - 1.4e-14 54.2 0.1 2.6e-14 53.3 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PSC73356.1 - 0.00022 21.0 1.9 0.016 15.1 0.2 3.1 2 1 0 2 2 2 1 PDZ domain PDZ PF00595.24 PSC73356.1 - 0.014 15.7 0.9 0.43 11.0 0.9 2.6 1 1 0 1 1 1 0 PDZ domain Peptidase_S29 PF02907.15 PSC73356.1 - 0.023 14.4 0.3 0.051 13.3 0.1 1.7 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease Tricorn_PDZ PF14685.6 PSC73356.1 - 0.067 13.2 0.0 0.16 11.9 0.0 1.7 1 0 0 1 1 1 0 Tricorn protease PDZ domain SMP PF04927.12 PSC73356.1 - 0.072 13.6 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 Seed maturation protein Trypsin_2 PF13365.6 PSC73357.1 - 5.3e-34 118.3 1.3 1e-33 117.3 1.3 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 PSC73357.1 - 5.4e-16 59.1 0.1 8.7e-16 58.4 0.1 1.3 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 PSC73357.1 - 1.6e-14 53.9 0.1 3e-14 53.1 0.1 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PSC73357.1 - 0.00022 21.0 1.9 0.016 15.1 0.2 3.1 2 1 0 2 2 2 1 PDZ domain Peptidase_S29 PF02907.15 PSC73357.1 - 0.024 14.4 0.3 0.051 13.3 0.1 1.7 2 0 0 2 2 2 0 Hepatitis C virus NS3 protease Tricorn_PDZ PF14685.6 PSC73357.1 - 0.059 13.3 0.0 0.16 12.0 0.0 1.8 1 0 0 1 1 1 0 Tricorn protease PDZ domain PDZ PF00595.24 PSC73357.1 - 0.07 13.5 0.6 0.81 10.1 0.6 2.5 1 1 0 1 1 1 0 PDZ domain SMP PF04927.12 PSC73357.1 - 0.072 13.6 0.0 0.24 11.9 0.0 1.8 1 0 0 1 1 1 0 Seed maturation protein LRR_8 PF13855.6 PSC73358.1 - 3.8e-05 23.4 7.4 0.062 13.1 0.2 4.5 4 1 2 6 6 6 3 Leucine rich repeat LRR_1 PF00560.33 PSC73358.1 - 0.00032 20.8 0.3 3.1 8.7 0.1 4.7 4 1 0 4 4 4 1 Leucine Rich Repeat LRR_4 PF12799.7 PSC73358.1 - 0.0028 18.0 0.9 4.2 7.9 0.4 4.1 4 0 0 4 4 4 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PSC73358.1 - 0.055 13.5 0.9 1e+02 3.4 0.0 4.0 3 0 0 3 3 3 0 Leucine Rich repeat Pinin_SDK_memA PF04696.13 PSC73359.1 - 2.3e-19 69.7 5.6 2.3e-19 69.7 5.6 3.2 2 1 1 3 3 3 1 pinin/SDK/memA/ protein conserved region Na_H_Exchanger PF00999.21 PSC73360.1 - 3.5e-52 177.5 46.6 3.5e-52 177.5 46.6 1.5 2 0 0 2 2 2 1 Sodium/hydrogen exchanger family TrkA_N PF02254.18 PSC73360.1 - 4.2e-17 62.5 0.0 4.2e-17 62.5 0.0 2.9 3 0 0 3 3 3 1 TrkA-N domain FAM76 PF16046.5 PSC73360.1 - 0.017 14.5 3.1 0.03 13.7 3.1 1.3 1 0 0 1 1 1 0 FAM76 protein Glyco_transf_8 PF01501.20 PSC73361.1 - 0.00032 20.4 0.0 0.00078 19.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 8 UPF0172 PF03665.13 PSC73363.1 - 4.3e-45 154.1 0.0 4.9e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) UPF0172 PF03665.13 PSC73364.1 - 4.3e-45 154.1 0.0 4.9e-45 153.9 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) Pkinase PF00069.25 PSC73365.1 - 5.5e-38 130.8 0.0 7.2e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73365.1 - 1.6e-20 73.5 0.0 2.1e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PSC73365.1 - 0.0066 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PSC73365.1 - 0.16 11.6 0.0 9.9 5.7 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Pkinase PF00069.25 PSC73366.1 - 5.6e-38 130.8 0.0 7.4e-38 130.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73366.1 - 1.6e-20 73.5 0.0 2.2e-20 73.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PSC73366.1 - 0.0067 15.8 0.0 0.011 15.2 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PSC73366.1 - 0.16 11.6 0.0 10 5.7 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ank_2 PF12796.7 PSC73367.1 - 1.5e-23 83.2 0.1 4.3e-16 59.3 0.0 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC73367.1 - 2e-21 76.1 1.7 1.9e-07 31.5 0.0 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PSC73367.1 - 3.9e-17 61.8 4.9 0.00049 20.4 0.0 4.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 PSC73367.1 - 5.6e-17 61.6 0.4 4.5e-06 26.8 0.0 3.9 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC73367.1 - 4.5e-13 48.1 0.1 0.072 13.7 0.0 5.4 5 0 0 5 5 5 4 Ankyrin repeat Peptidase_S8 PF00082.22 PSC73368.1 - 1.6e-34 119.5 12.5 1.6e-34 119.5 12.5 1.8 2 0 0 2 2 2 1 Subtilase family RNase_T PF00929.24 PSC73368.1 - 0.002 18.7 0.0 0.22 12.1 0.0 2.2 2 0 0 2 2 2 2 Exonuclease VSP PF03302.13 PSC73368.1 - 2.9 6.7 76.3 0.47 9.2 23.5 3.4 1 1 2 3 3 3 0 Giardia variant-specific surface protein Sulfotransfer_2 PF03567.14 PSC73369.1 - 7.4e-05 22.8 0.1 0.00012 22.0 0.1 1.4 1 0 0 1 1 1 1 Sulfotransferase family DUF2681 PF10883.8 PSC73369.1 - 0.058 13.8 2.3 0.079 13.4 0.7 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Elong-fact-P_C PF09285.11 PSC73370.1 - 7.1e-28 96.1 0.2 1.7e-27 95.0 0.2 1.7 1 0 0 1 1 1 1 Elongation factor P, C-terminal EFP_N PF08207.12 PSC73370.1 - 4.1e-27 94.0 0.6 8.6e-27 92.9 0.1 1.8 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain EFP PF01132.20 PSC73370.1 - 1e-17 63.9 1.6 1.7e-17 63.2 1.6 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) OB domain Cyto_heme_lyase PF01265.17 PSC73371.1 - 1.1e-42 146.6 5.0 1e-41 143.5 5.0 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase IQ PF00612.27 PSC73372.1 - 8.9e-42 137.0 163.7 2.9e-05 23.5 0.5 19.7 18 1 1 19 19 19 18 IQ calmodulin-binding motif CH PF00307.31 PSC73372.1 - 5.9e-13 48.9 0.0 0.0058 16.8 0.0 4.6 5 0 0 5 5 5 3 Calponin homology (CH) domain CAMSAP_CH PF11971.8 PSC73372.1 - 0.009 15.8 0.2 2 8.3 0.0 3.2 4 0 0 4 4 4 1 CAMSAP CH domain Metallophos PF00149.28 PSC73373.1 - 9.7e-18 65.4 1.2 7.3e-08 33.2 0.5 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 PSC73373.1 - 1.5e-10 41.5 0.0 3.3e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 PSC73373.1 - 2e-08 35.0 2.5 5.5e-08 33.6 0.1 3.0 4 0 0 4 4 4 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 PSC73373.1 - 0.0013 19.0 0.1 2.2 8.4 0.1 2.3 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain RskA PF10099.9 PSC73373.1 - 0.64 10.3 15.4 0.041 14.2 4.7 2.5 2 0 0 2 2 2 0 Anti-sigma-K factor rskA Med3 PF11593.8 PSC73373.1 - 2.2 7.4 4.6 3.8 6.6 4.6 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF5619 PF18505.1 PSC73373.1 - 4.2 7.4 5.8 1.9 8.5 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5619) DNA_pol_B PF00136.21 PSC73374.1 - 1.6e-71 241.4 0.0 3.2e-71 240.4 0.0 1.5 1 1 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 PSC73374.1 - 6.3e-10 38.7 0.0 0.00017 20.9 0.0 2.6 3 0 0 3 3 3 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 PSC73374.1 - 4.7e-06 27.0 0.8 8.6e-06 26.1 0.8 1.5 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Adaptin_N PF01602.20 PSC73375.1 - 8.7e-91 305.0 0.0 1.1e-90 304.7 0.0 1.0 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 PSC73375.1 - 5e-07 30.0 0.0 8e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Adaptin C-terminal domain Alpha_adaptin_C PF02296.16 PSC73375.1 - 7.5e-06 26.1 0.0 1.5e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Alpha adaptin AP2, C-terminal domain Cnd1 PF12717.7 PSC73375.1 - 2.8e-05 24.2 0.1 0.0046 17.0 0.0 2.2 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PSC73375.1 - 0.96 9.9 3.8 25 5.5 0.1 3.8 3 0 0 3 3 3 0 HEAT repeat rve PF00665.26 PSC73376.1 - 2e-18 66.7 0.0 4.3e-18 65.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC73376.1 - 0.014 15.2 0.0 0.039 13.7 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Peptidase_M16_M PF16187.5 PSC73378.1 - 3.5e-69 233.2 0.0 6.3e-69 232.4 0.0 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 PSC73378.1 - 3.6e-32 111.4 0.1 1.5e-31 109.4 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 PSC73378.1 - 7.2e-26 91.3 0.0 9.6e-12 45.3 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain mTERF PF02536.14 PSC73379.1 - 2.9e-45 154.5 0.0 3.6e-24 85.3 0.0 2.1 1 1 1 2 2 2 2 mTERF TrbM PF07424.11 PSC73379.1 - 0.084 12.8 0.0 0.33 10.9 0.0 1.9 1 1 1 2 2 2 0 TrbM Methyltransf_11 PF08241.12 PSC73382.1 - 5.5e-23 81.4 0.0 8.8e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC73382.1 - 3.9e-22 78.8 0.0 6.3e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC73382.1 - 3.2e-20 72.5 0.0 5.1e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC73382.1 - 5e-19 68.7 0.0 7.6e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC73382.1 - 1.9e-17 63.8 0.0 4.9e-17 62.5 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC73382.1 - 4.1e-14 52.5 0.0 7.2e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 PSC73382.1 - 1.4e-12 47.5 0.0 2.1e-12 46.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_29 PF03141.16 PSC73382.1 - 2.2e-08 33.1 0.0 2.9e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_4 PF02390.17 PSC73382.1 - 3.4e-07 29.9 0.0 3.5e-05 23.3 0.0 2.2 2 0 0 2 2 2 1 Putative methyltransferase TehB PF03848.14 PSC73382.1 - 2e-06 27.3 0.0 3.2e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MetW PF07021.12 PSC73382.1 - 0.00019 21.1 0.0 0.0003 20.4 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW MTS PF05175.14 PSC73382.1 - 0.00067 19.2 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 PSC73382.1 - 0.0007 19.2 0.0 0.0011 18.5 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase DREV PF05219.12 PSC73382.1 - 0.0015 17.7 0.0 0.0023 17.1 0.0 1.2 1 0 0 1 1 1 1 DREV methyltransferase PCMT PF01135.19 PSC73382.1 - 0.0025 17.6 0.0 0.0033 17.2 0.0 1.1 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 PSC73382.1 - 0.0081 16.3 0.0 0.1 12.7 0.0 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase NodS PF05401.11 PSC73382.1 - 0.01 15.4 0.0 0.015 14.9 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 PSC73382.1 - 0.017 15.1 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_20 PF12147.8 PSC73382.1 - 0.056 12.6 0.0 0.085 12.0 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_8 PF05148.15 PSC73382.1 - 0.078 12.8 0.0 0.16 11.8 0.0 1.5 2 0 0 2 2 2 0 Hypothetical methyltransferase NAS PF03059.16 PSC73382.1 - 0.081 12.2 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Nicotianamine synthase protein Methyltransf_24 PF13578.6 PSC73382.1 - 0.14 13.2 0.0 0.28 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Proteasome PF00227.26 PSC73383.1 - 2.7e-25 88.9 0.8 3.5e-24 85.4 0.4 2.3 1 1 0 1 1 1 1 Proteasome subunit Peptidase_M3 PF01432.20 PSC73384.1 - 2.1e-128 429.5 0.0 2.8e-128 429.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 AAA_2 PF07724.14 PSC73384.1 - 3.1e-56 190.2 0.1 2.4e-54 184.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) Clp_N PF02861.20 PSC73384.1 - 3.4e-36 123.2 8.3 1.2e-17 63.7 0.1 4.2 4 0 0 4 4 3 2 Clp amino terminal domain, pathogenicity island component MCU PF04678.13 PSC73384.1 - 6.5e-34 117.6 0.5 8.2e-33 114.0 0.0 2.9 2 0 0 2 2 2 1 Mitochondrial calcium uniporter AAA_lid_9 PF17871.1 PSC73384.1 - 1.3e-32 111.8 2.2 1.3e-32 111.8 2.2 2.3 2 0 0 2 2 1 1 AAA lid domain ClpB_D2-small PF10431.9 PSC73384.1 - 1.1e-24 86.2 0.4 3.4e-24 84.7 0.4 1.9 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 PSC73384.1 - 1.2e-21 77.5 0.0 8.3e-13 48.9 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PSC73384.1 - 2.1e-16 60.2 0.0 2e-10 40.8 0.0 2.7 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PSC73384.1 - 2.1e-10 41.2 1.8 1.1e-05 25.8 0.0 4.6 3 0 0 3 3 2 2 AAA ATPase domain Sigma54_activat PF00158.26 PSC73384.1 - 4.6e-07 29.7 0.1 0.00018 21.3 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain UVR PF02151.19 PSC73384.1 - 1.9e-06 27.4 4.6 1.9e-06 27.4 4.6 2.6 2 0 0 2 2 2 1 UvrB/uvrC motif TniB PF05621.11 PSC73384.1 - 2.6e-05 23.7 0.1 0.0011 18.4 0.0 3.1 3 1 0 3 3 3 1 Bacterial TniB protein AAA_22 PF13401.6 PSC73384.1 - 7e-05 23.1 3.0 0.13 12.6 0.4 4.3 2 2 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 PSC73384.1 - 9.9e-05 22.1 0.0 0.1 12.3 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.6 PSC73384.1 - 0.00033 21.2 0.2 0.64 10.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 PSC73384.1 - 0.00055 20.0 0.0 1.4 8.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 PSC73384.1 - 0.00064 19.7 0.0 0.052 13.5 0.0 3.0 3 0 0 3 3 3 1 NACHT domain RNA_helicase PF00910.22 PSC73384.1 - 0.0011 19.3 0.0 2.1 8.8 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_25 PF13481.6 PSC73384.1 - 0.0018 17.9 0.1 0.033 13.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 PSC73384.1 - 0.0021 17.4 0.0 0.45 9.8 0.0 3.3 3 0 0 3 3 3 1 Zeta toxin RsgA_GTPase PF03193.16 PSC73384.1 - 0.0045 16.9 0.1 2.6 7.9 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_33 PF13671.6 PSC73384.1 - 0.0078 16.4 0.0 8.3 6.6 0.0 3.2 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 PSC73384.1 - 0.014 15.1 0.0 7.5 6.2 0.0 2.6 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 PSC73384.1 - 0.015 14.7 0.2 6.7 6.0 0.0 3.2 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase_2 PF01637.18 PSC73384.1 - 0.016 15.1 0.8 4.3 7.2 0.1 3.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea DnaJ_CXXCXGXG PF00684.19 PSC73384.1 - 0.022 15.1 7.1 0.051 13.9 7.1 1.6 1 0 0 1 1 1 0 DnaJ central domain AAA_7 PF12775.7 PSC73384.1 - 0.054 13.0 0.0 13 5.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region TsaE PF02367.17 PSC73384.1 - 0.063 13.3 0.0 3.2 7.8 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SUIM_assoc PF16619.5 PSC73384.1 - 0.094 12.8 14.2 0.16 12.0 5.4 2.9 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 AAA_3 PF07726.11 PSC73384.1 - 0.096 12.5 0.0 3.8 7.4 0.0 2.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 PSC73384.1 - 0.12 12.4 0.1 11 5.9 0.0 3.0 2 1 0 3 3 3 0 Type III restriction enzyme, res subunit UPF0167 PF03691.14 PSC73384.1 - 0.16 11.7 1.9 0.42 10.4 1.9 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0167) Peptidase_M50B PF13398.6 PSC73384.1 - 0.17 11.5 0.1 0.31 10.7 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like DNA_pol3_delta2 PF13177.6 PSC73384.1 - 0.17 11.6 0.0 6 6.6 0.0 2.4 2 0 0 2 2 2 0 DNA polymerase III, delta subunit RuvB_N PF05496.12 PSC73384.1 - 0.2 11.4 3.1 18 5.1 0.0 3.8 3 1 0 3 3 3 0 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 PSC73384.1 - 0.4 10.9 3.5 29 4.9 0.1 3.9 3 0 0 3 3 2 0 AAA domain Anti-TRAP PF15777.5 PSC73384.1 - 1.9 8.5 5.1 5.1 7.1 5.1 1.7 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Abhydrolase_1 PF00561.20 PSC73386.1 - 1.3e-19 70.8 0.0 2.7e-13 50.1 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PSC73386.1 - 4.5e-16 60.1 7.8 4.5e-16 60.1 7.8 3.0 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PSC73386.1 - 6.9e-10 38.6 0.0 0.00084 18.7 0.0 2.4 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 PSC73386.1 - 0.00061 19.9 0.0 0.0036 17.4 0.0 2.2 2 0 0 2 2 2 1 TAP-like protein DLH PF01738.18 PSC73386.1 - 0.001 18.7 0.0 0.0016 18.0 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 PSC73386.1 - 0.0046 16.5 0.0 0.0072 15.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Ndr PF03096.14 PSC73386.1 - 0.0097 14.6 0.0 0.015 14.0 0.0 1.2 1 0 0 1 1 1 1 Ndr family FSH1 PF03959.13 PSC73386.1 - 0.043 13.5 0.0 0.13 11.9 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) ABC_membrane_2 PF06472.15 PSC73387.1 - 2.6e-44 151.7 0.1 9.4e-29 100.6 0.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.27 PSC73387.1 - 3.1e-19 69.9 0.0 6.9e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 ABC transporter MMADHC PF10229.9 PSC73387.1 - 2.2e-11 44.0 0.0 4e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein AAA_29 PF13555.6 PSC73387.1 - 5.7e-05 22.8 0.1 0.0016 18.1 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain Rad17 PF03215.15 PSC73387.1 - 0.00011 22.2 0.1 0.00021 21.3 0.1 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_23 PF13476.6 PSC73387.1 - 0.00012 22.6 2.1 0.00029 21.4 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 PSC73387.1 - 0.0026 17.6 0.3 0.0046 16.8 0.1 1.5 2 0 0 2 2 1 1 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PSC73387.1 - 0.011 15.2 0.0 0.099 12.1 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 PSC73387.1 - 0.016 15.1 0.1 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 PSC73387.1 - 0.065 13.5 0.0 0.27 11.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain TFIIA PF03153.13 PSC73387.1 - 0.082 12.9 4.3 0.15 12.0 4.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FtsK_SpoIIIE PF01580.18 PSC73387.1 - 0.1 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.6 PSC73387.1 - 0.11 12.9 0.1 0.11 12.9 0.1 4.0 3 1 1 4 4 4 0 AAA ATPase domain DUF815 PF05673.13 PSC73387.1 - 0.13 11.4 0.1 0.33 10.1 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA PF00004.29 PSC73387.1 - 0.13 12.7 0.3 0.28 11.6 0.3 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Adeno_IVa2 PF02456.15 PSC73387.1 - 0.32 9.7 0.1 0.53 9.0 0.1 1.2 1 0 0 1 1 1 0 Adenovirus IVa2 protein AAA_15 PF13175.6 PSC73387.1 - 0.32 10.6 0.0 0.45 10.2 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 PSC73387.1 - 0.36 11.4 0.7 2.1 8.9 0.2 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 PSC73387.1 - 7.5 6.7 7.2 1.3 9.2 0.1 3.0 3 0 0 3 3 3 0 AAA domain Peptidase_M22 PF00814.25 PSC73388.1 - 1.4e-87 293.9 0.0 1.4e-87 293.9 0.0 2.0 2 0 0 2 2 2 1 Glycoprotease family Ccdc124 PF06244.12 PSC73388.1 - 2.4e-24 86.3 37.1 6.4e-21 75.3 37.1 2.4 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 Carbam_trans_N PF02543.15 PSC73388.1 - 0.0059 16.3 0.0 0.26 10.9 0.0 2.4 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus ATP-synt_J PF04911.12 PSC73388.1 - 0.072 12.7 1.3 0.086 12.4 0.1 1.8 2 0 0 2 2 2 0 ATP synthase j chain Peptidase_M22 PF00814.25 PSC73389.1 - 3.6e-83 279.4 4.6 5.9e-83 278.7 0.0 2.7 2 1 0 2 2 2 1 Glycoprotease family Ccdc124 PF06244.12 PSC73389.1 - 2e-24 86.6 36.7 5.2e-21 75.5 36.7 2.4 1 1 0 1 1 1 1 Coiled-coil domain-containing protein 124 /Oxs1 Carbam_trans_N PF02543.15 PSC73389.1 - 0.0064 16.2 0.0 0.27 10.9 0.0 2.4 2 0 0 2 2 2 1 Carbamoyltransferase N-terminus ATP-synt_J PF04911.12 PSC73389.1 - 0.075 12.6 1.3 0.089 12.4 0.1 1.8 2 0 0 2 2 2 0 ATP synthase j chain Ribosomal_L28 PF00830.19 PSC73390.1 - 1.1e-16 60.8 0.1 2e-16 59.9 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L28 family BRF1 PF07741.13 PSC73390.1 - 0.003 17.9 0.1 0.0052 17.1 0.1 1.4 1 0 0 1 1 1 1 Brf1-like TBP-binding domain TERB2 PF15101.6 PSC73390.1 - 0.042 13.9 0.4 0.054 13.5 0.4 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Terminase_4 PF05119.12 PSC73390.1 - 0.053 14.0 1.8 0.093 13.2 1.7 1.6 1 1 0 1 1 1 0 Phage terminase, small subunit RGP PF03214.13 PSC73391.1 - 2.5e-161 536.6 0.1 7.9e-117 390.2 0.0 2.1 2 0 0 2 2 2 2 Reversibly glycosylated polypeptide Actin PF00022.19 PSC73391.1 - 3.3e-95 319.1 0.0 9e-95 317.7 0.0 1.6 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 PSC73391.1 - 0.0057 15.5 0.1 0.14 10.9 0.0 2.1 2 0 0 2 2 2 1 MreB/Mbl protein 3HCDH_N PF02737.18 PSC73392.1 - 1.9e-58 197.3 0.2 3.6e-58 196.4 0.2 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ECH_1 PF00378.20 PSC73392.1 - 3.7e-46 157.5 0.1 6.4e-46 156.7 0.1 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase 3HCDH PF00725.22 PSC73392.1 - 3.7e-30 104.4 0.1 4e-24 85.1 0.0 2.7 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain ECH_2 PF16113.5 PSC73392.1 - 5.2e-28 98.5 0.0 1.1e-27 97.4 0.0 1.5 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase F5_F8_type_C PF00754.25 PSC73392.1 - 0.00054 20.1 4.3 0.0057 16.8 0.1 2.7 3 0 0 3 3 3 1 F5/8 type C domain CLP_protease PF00574.23 PSC73393.1 - 3.3e-80 268.3 0.0 4e-80 268.0 0.0 1.1 1 0 0 1 1 1 1 Clp protease O-FucT PF10250.9 PSC73394.1 - 1.6e-12 47.8 0.0 3e-11 43.6 0.0 2.2 1 1 0 1 1 1 1 GDP-fucose protein O-fucosyltransferase ARID PF01388.21 PSC73395.1 - 1.8e-12 47.8 0.0 4.6e-12 46.4 0.0 1.7 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain Acetyltransf_1 PF00583.25 PSC73395.1 - 2.5e-12 47.1 0.0 5.1e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PSC73395.1 - 8.8e-12 45.1 0.0 1.8e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PSC73395.1 - 4.2e-11 43.1 0.0 8.6e-11 42.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC73395.1 - 2.9e-09 36.8 0.0 1.1e-08 34.9 0.0 1.9 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 PSC73395.1 - 5.4e-06 26.5 0.0 1.4e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DDT PF02791.17 PSC73395.1 - 0.003 17.8 0.2 0.008 16.5 0.0 1.8 2 0 0 2 2 2 1 DDT domain WHIM1 PF15612.6 PSC73395.1 - 0.032 13.8 0.0 0.11 12.1 0.0 1.9 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 GNAT_acetyltran PF12746.7 PSC73395.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase Tmemb_14 PF03647.13 PSC73398.1 - 7.8e-07 29.7 6.8 1e-06 29.4 6.8 1.2 1 0 0 1 1 1 1 Transmembrane proteins 14C AAA PF00004.29 PSC73399.1 - 1e-11 45.4 0.0 1.6e-11 44.7 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Phage_F PF02305.17 PSC73399.1 - 0.067 11.9 0.0 0.1 11.4 0.0 1.2 1 0 0 1 1 1 0 Capsid protein (F protein) RRS1 PF04939.12 PSC73400.1 - 1.5e-52 177.7 0.4 1.5e-52 177.7 0.4 1.8 2 1 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) CK1gamma_C PF12605.8 PSC73400.1 - 9.3 7.5 8.6 5.6 8.2 0.4 3.0 2 1 0 2 2 2 0 Casein kinase 1 gamma C terminal Trehalase PF01204.18 PSC73401.1 - 2.1e-138 462.3 0.0 2.8e-138 462.0 0.0 1.1 1 0 0 1 1 1 1 Trehalase 2OG-FeII_Oxy_3 PF13640.6 PSC73401.1 - 1e-15 58.4 0.0 1.8e-15 57.6 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 PSC73401.1 - 8.5e-08 32.6 7.3 2.3e-07 31.3 7.3 1.8 1 0 0 1 1 1 1 ShK domain-like 2OG-FeII_Oxy PF03171.20 PSC73401.1 - 5.3e-05 23.7 0.0 0.0001 22.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Glyco_hydro_63 PF03200.16 PSC73401.1 - 0.00074 18.4 0.0 0.0028 16.5 0.0 1.8 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Bac_rhamnosid6H PF17389.2 PSC73401.1 - 0.037 13.3 0.0 0.091 12.0 0.0 1.6 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF4148 PF13663.6 PSC73401.1 - 0.67 10.2 5.8 36 4.6 0.0 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) PsbP PF01789.16 PSC73402.1 - 7.1e-23 81.5 0.0 7.9e-23 81.3 0.0 1.1 1 0 0 1 1 1 1 PsbP UDPGP PF01704.18 PSC73403.1 - 2.6e-122 408.4 0.0 3.1e-122 408.2 0.0 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase AA_kinase PF00696.28 PSC73404.1 - 5.3e-15 55.7 2.2 2.4e-14 53.5 2.2 1.9 1 1 0 1 1 1 1 Amino acid kinase family Acetyltransf_1 PF00583.25 PSC73404.1 - 5.2e-08 33.1 0.0 1e-07 32.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PSC73404.1 - 3.4e-07 30.6 0.0 1e-06 29.1 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PSC73404.1 - 0.00041 20.3 0.0 0.00088 19.2 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain SF3A2 PF16835.5 PSC73405.1 - 2.8e-35 120.6 0.1 4.4e-35 119.9 0.1 1.3 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 PSC73405.1 - 2.2e-06 27.9 0.6 3.6e-06 27.2 0.6 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 PSC73405.1 - 0.00065 19.6 0.1 0.0011 19.0 0.1 1.3 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Pkinase PF00069.25 PSC73406.1 - 5.2e-44 150.6 0.0 1e-43 149.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73406.1 - 9.2e-44 149.7 0.0 3.4e-43 147.8 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_4 PF12799.7 PSC73406.1 - 2.5e-24 84.9 4.5 0.013 15.9 0.0 8.3 5 1 6 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC73406.1 - 8e-17 60.8 15.1 0.00012 21.7 0.2 8.0 4 3 3 8 8 8 8 Leucine rich repeat LRR_1 PF00560.33 PSC73406.1 - 2.5e-07 30.3 10.2 10 7.1 0.0 10.4 12 0 0 12 12 12 1 Leucine Rich Repeat LRR_2 PF07723.13 PSC73406.1 - 0.15 12.8 1.6 51 4.8 0.0 4.2 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.6 PSC73406.1 - 0.55 10.4 11.4 13 6.2 0.1 6.7 8 0 0 8 8 8 0 Leucine Rich repeat p450 PF00067.22 PSC73407.1 - 3.9e-66 223.7 0.0 8.7e-66 222.5 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Lactamase_B PF00753.27 PSC73407.1 - 3.8e-19 69.5 6.7 1.1e-17 64.7 3.1 2.7 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily His_Phos_1 PF00300.22 PSC73407.1 - 1.4e-12 47.7 2.0 4.2e-11 42.9 0.3 2.9 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) Lactamase_B_2 PF12706.7 PSC73407.1 - 1.4e-09 37.7 0.4 4.3e-09 36.2 0.4 1.8 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 PSC73407.1 - 0.0022 17.4 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Ribosomal_60s PF00428.19 PSC73407.1 - 0.01 16.4 11.5 0.01 16.4 11.5 4.9 4 0 0 4 4 4 0 60s Acidic ribosomal protein p450 PF00067.22 PSC73408.1 - 3.8e-66 223.7 0.0 8.6e-66 222.6 0.0 1.4 1 1 0 1 1 1 1 Cytochrome P450 Lactamase_B PF00753.27 PSC73408.1 - 4.6e-15 56.2 8.7 1.6e-13 51.1 5.0 2.8 2 1 0 2 2 2 2 Metallo-beta-lactamase superfamily His_Phos_1 PF00300.22 PSC73408.1 - 1.7e-12 47.5 2.3 4.2e-11 42.9 0.3 2.9 3 0 0 3 3 3 1 Histidine phosphatase superfamily (branch 1) Lactamase_B_2 PF12706.7 PSC73408.1 - 4.4e-08 32.9 0.3 1.3e-07 31.3 0.3 1.8 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_6 PF16661.5 PSC73408.1 - 0.0024 17.3 0.0 0.0039 16.6 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Ribosomal_60s PF00428.19 PSC73408.1 - 0.01 16.4 11.5 0.01 16.4 11.5 4.9 4 0 0 4 4 4 0 60s Acidic ribosomal protein HTH_9 PF08221.11 PSC73409.1 - 6.3e-12 45.4 0.1 2.6e-09 37.0 0.1 3.4 3 0 0 3 3 3 1 RNA polymerase III subunit RPC82 helix-turn-helix domain TFIIE_alpha PF02002.17 PSC73409.1 - 1.4e-07 31.3 0.0 0.015 15.2 0.0 2.7 2 0 0 2 2 2 2 TFIIE alpha subunit RNA_pol_Rpc82 PF05645.13 PSC73409.1 - 2.1e-06 27.7 0.0 3.6e-05 23.7 0.0 2.3 1 1 1 2 2 2 1 RNA polymerase III subunit RPC82 DprA_WH PF17782.1 PSC73409.1 - 0.0056 16.8 0.9 0.027 14.6 0.1 2.6 2 0 0 2 2 2 1 DprA winged helix domain Adeno_terminal PF02459.15 PSC73409.1 - 0.12 10.8 0.5 0.23 9.8 0.5 1.4 1 0 0 1 1 1 0 Adenoviral DNA terminal protein HTH_IclR PF09339.10 PSC73409.1 - 0.17 11.7 1.4 0.72 9.7 0.0 2.8 3 0 0 3 3 3 0 IclR helix-turn-helix domain ASFV_J13L PF05568.11 PSC73409.1 - 5.3 6.8 5.8 9.5 5.9 5.8 1.3 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF1772 PF08592.11 PSC73410.1 - 0.0015 18.9 1.7 0.0019 18.5 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) UbiA PF01040.18 PSC73410.1 - 0.015 14.6 7.0 0.019 14.3 7.0 1.1 1 0 0 1 1 1 0 UbiA prenyltransferase family TMEM208_SND2 PF05620.11 PSC73410.1 - 0.023 14.5 1.1 0.023 14.5 1.1 1.6 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 UL73_N PF12522.8 PSC73410.1 - 0.08 12.7 3.4 0.21 11.4 3.4 1.7 1 0 0 1 1 1 0 Cytomegalovirus glycoprotein N terminal HCV_NS4a PF01006.20 PSC73410.1 - 0.47 10.2 3.6 1 9.2 3.3 1.6 1 1 0 1 1 1 0 Hepatitis C virus non-structural protein NS4a Rrn6 PF10214.9 PSC73410.1 - 1.2 7.6 5.4 1.7 7.0 5.4 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Pex14_N PF04695.13 PSC73410.1 - 9.4 6.9 14.8 0.14 12.8 6.4 1.9 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DnaJ_C PF01556.18 PSC73411.1 - 4e-37 127.6 0.0 5.6e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PSC73411.1 - 9.7e-28 96.1 1.2 1.7e-27 95.3 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 PSC73412.1 - 3.9e-37 127.6 0.0 5.8e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PSC73412.1 - 9.9e-28 96.1 1.2 1.7e-27 95.3 1.2 1.4 1 0 0 1 1 1 1 DnaJ domain LSM PF01423.22 PSC73413.1 - 2.2e-15 56.1 0.1 4.2e-15 55.2 0.1 1.4 1 0 0 1 1 1 1 LSM domain FlaC_arch PF05377.11 PSC73413.1 - 0.23 11.9 3.3 21 5.6 0.0 5.9 6 0 0 6 6 6 0 Flagella accessory protein C (FlaC) Pox_A_type_inc PF04508.12 PSC73413.1 - 4.6 7.3 7.6 11 6.1 0.1 4.3 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat IMUP PF15761.5 PSC73414.1 - 0.12 13.1 5.3 0.13 12.9 5.3 1.2 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF1180 PF06679.12 PSC73414.1 - 2.6 8.4 4.8 3 8.2 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) B3 PF02362.21 PSC73415.1 - 0.00047 20.0 0.0 0.00097 19.0 0.0 1.5 1 0 0 1 1 1 1 B3 DNA binding domain Chromo PF00385.24 PSC73415.1 - 0.00084 19.2 0.0 0.0018 18.1 0.0 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain LRR_4 PF12799.7 PSC73417.1 - 9.4e-13 48.1 0.0 0.0063 16.9 0.0 5.8 6 0 0 6 6 6 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC73417.1 - 1.6e-08 34.2 9.3 0.005 16.6 0.6 5.7 7 0 0 7 7 7 2 Leucine rich repeat LRR_1 PF00560.33 PSC73417.1 - 1.8e-06 27.7 5.7 4.5 8.2 0.1 6.7 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 PSC73417.1 - 0.00016 21.5 3.8 12 6.2 0.1 6.2 7 0 0 7 7 7 2 Leucine Rich repeat F-box-like PF12937.7 PSC73417.1 - 0.0056 16.5 0.7 0.05 13.5 0.2 2.6 2 0 0 2 2 2 1 F-box-like DUF2849 PF11011.8 PSC73418.1 - 0.033 14.8 1.9 0.033 14.8 1.9 2.9 2 1 2 4 4 4 0 Protein of unknown function (DUF2849) Peptidase_C1 PF00112.23 PSC73419.1 - 2.5e-19 70.2 1.3 6.8e-16 59.0 0.1 3.0 2 1 1 3 3 3 2 Papain family cysteine protease PAN_4 PF14295.6 PSC73419.1 - 1.2e-11 44.3 7.7 1.1e-06 28.5 2.5 4.7 5 0 0 5 5 5 2 PAN domain Gal_Lectin PF02140.18 PSC73419.1 - 2.1e-11 44.1 0.1 0.00045 20.6 0.0 3.4 2 1 0 2 2 2 2 Galactose binding lectin domain PAN_1 PF00024.26 PSC73419.1 - 6.1e-05 22.9 8.8 0.00069 19.5 0.2 3.2 3 0 0 3 3 3 2 PAN domain Peptidase_C1 PF00112.23 PSC73420.1 - 5.7e-18 65.8 1.9 1.1e-14 55.1 0.2 3.0 2 1 1 3 3 3 2 Papain family cysteine protease PAN_4 PF14295.6 PSC73420.1 - 1.2e-11 44.3 7.7 1.1e-06 28.5 2.4 4.7 5 0 0 5 5 5 2 PAN domain Gal_Lectin PF02140.18 PSC73420.1 - 2.1e-11 44.1 0.1 0.00045 20.6 0.0 3.4 2 1 0 2 2 2 2 Galactose binding lectin domain PAN_1 PF00024.26 PSC73420.1 - 6e-05 22.9 8.8 0.00069 19.5 0.2 3.2 3 0 0 3 3 3 2 PAN domain Ribosomal_S28e PF01200.18 PSC73421.1 - 2.6e-32 110.6 1.6 2.9e-32 110.5 1.6 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Ring_hydroxyl_A PF00848.19 PSC73422.1 - 5.3e-34 118.1 0.0 1.6e-33 116.5 0.0 1.8 2 0 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 PSC73422.1 - 9.9e-15 54.3 0.0 1.8e-14 53.5 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Thioredoxin PF00085.20 PSC73422.1 - 6.7e-05 22.8 0.0 0.00012 22.1 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Ring_hydroxyl_A PF00848.19 PSC73423.1 - 8.5e-30 104.3 0.0 3e-29 102.5 0.0 1.9 2 0 0 2 2 2 1 Ring hydroxylating alpha subunit (catalytic domain) Rieske PF00355.26 PSC73423.1 - 9.1e-15 54.4 0.0 1.6e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Thioredoxin PF00085.20 PSC73423.1 - 6.2e-05 22.9 0.0 0.00011 22.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin SRP54 PF00448.22 PSC73424.1 - 1.9e-72 243.0 0.0 3.4e-72 242.2 0.0 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP54_N PF02881.19 PSC73424.1 - 1.1e-09 38.4 0.1 2.6e-09 37.1 0.0 1.7 1 1 0 1 1 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 PSC73424.1 - 7.1e-05 22.6 0.3 0.00015 21.6 0.3 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 PSC73424.1 - 0.0002 20.7 0.0 0.00033 20.0 0.0 1.3 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.6 PSC73424.1 - 0.00034 21.0 0.1 0.0033 17.8 0.0 2.4 2 1 1 3 3 3 1 AAA domain CbiA PF01656.23 PSC73424.1 - 0.001 19.1 0.0 0.003 17.6 0.0 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_28 PF13521.6 PSC73424.1 - 0.0011 19.2 0.0 0.0019 18.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PSC73424.1 - 0.0015 18.8 0.1 0.0045 17.3 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PSC73424.1 - 0.0021 18.5 0.1 0.0049 17.3 0.1 1.7 1 0 0 1 1 1 1 AAA ATPase domain NACHT PF05729.12 PSC73424.1 - 0.0057 16.6 2.6 0.54 10.2 2.6 2.4 1 1 0 1 1 1 1 NACHT domain DUF853 PF05872.12 PSC73424.1 - 0.011 14.3 0.7 0.023 13.3 0.2 1.7 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) AAA_33 PF13671.6 PSC73424.1 - 0.012 15.8 0.0 0.021 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 PSC73424.1 - 0.015 15.7 0.0 0.028 14.8 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 PSC73424.1 - 0.019 14.8 0.1 0.041 13.8 0.1 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase PG_isomerase_N PF18353.1 PSC73424.1 - 0.021 15.2 2.2 0.035 14.5 0.5 2.1 2 1 0 2 2 2 0 Phosphoglucose isomerase N-terminal domain VirC1 PF07015.11 PSC73424.1 - 0.027 13.8 0.1 0.054 12.8 0.1 1.4 1 0 0 1 1 1 0 VirC1 protein AAA_19 PF13245.6 PSC73424.1 - 0.07 13.5 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 PSC73424.1 - 0.13 12.8 0.2 0.35 11.4 0.1 1.7 1 1 1 2 2 2 0 ABC transporter DUF2075 PF09848.9 PSC73424.1 - 0.15 11.3 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MobB PF03205.14 PSC73424.1 - 0.18 11.7 0.5 0.41 10.5 0.5 1.7 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Thymidylate_kin PF02223.17 PSC73424.1 - 0.19 11.4 0.4 0.47 10.1 0.3 1.8 2 1 0 2 2 2 0 Thymidylate kinase Thiolase_N PF00108.23 PSC73425.1 - 4.7e-72 242.5 0.0 7.5e-72 241.8 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 PSC73425.1 - 3.6e-46 155.8 0.3 3.6e-46 155.8 0.3 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 PSC73425.1 - 0.0025 17.4 6.9 0.0047 16.5 1.2 3.6 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 PSC73425.1 - 0.0059 16.7 0.0 0.015 15.5 0.0 1.7 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal UCR_Fe-S_N PF10399.9 PSC73426.1 - 3.2 7.2 10.9 0.14 11.5 1.8 3.5 3 1 0 3 3 3 0 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal PDEase_I PF00233.19 PSC73427.1 - 4.7e-81 272.0 0.1 6.8e-81 271.5 0.1 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Ion_trans PF00520.31 PSC73427.1 - 0.017 14.3 4.2 0.014 14.6 1.3 2.0 2 0 0 2 2 2 0 Ion transport protein Per1 PF04080.13 PSC73427.1 - 0.047 13.5 0.4 0.099 12.4 0.4 1.5 1 0 0 1 1 1 0 Per1-like family RNA_pol_Rpb2_6 PF00562.28 PSC73428.1 - 2.9e-121 405.2 0.0 4.1e-121 404.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 PSC73428.1 - 2.1e-51 174.3 0.0 2.9e-51 173.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_4 PF04566.13 PSC73428.1 - 3.5e-23 81.7 1.0 3.5e-23 81.7 1.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.14 PSC73428.1 - 7.8e-22 77.8 0.1 1.2e-20 73.9 0.1 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 PSC73428.1 - 1.3e-20 73.3 0.0 2.9e-20 72.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 PSC73428.1 - 1.5e-20 73.4 0.4 3.8e-20 72.1 0.4 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_5 PF04567.17 PSC73428.1 - 3.7e-08 33.8 0.1 1.5e-07 31.9 0.1 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 cwf18 PF08315.12 PSC73428.1 - 0.049 14.3 0.1 0.092 13.4 0.1 1.4 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor Skp1 PF01466.19 PSC73429.1 - 3.6e-10 39.8 0.0 1.8e-09 37.6 0.0 2.3 1 0 0 1 1 1 1 Skp1 family, dimerisation domain Aa_trans PF01490.18 PSC73430.1 - 2.5e-07 29.8 3.0 4.6e-07 28.9 0.0 2.0 2 0 0 2 2 2 1 Transmembrane amino acid transporter protein SLC3A2_N PF16028.5 PSC73430.1 - 0.015 14.9 0.2 0.37 10.4 0.2 2.5 2 0 0 2 2 2 0 Solute carrier family 3 member 2 N-terminus COX14 PF14880.6 PSC73430.1 - 0.092 12.6 4.3 0.097 12.5 0.3 2.6 3 0 0 3 3 3 0 Cytochrome oxidase c assembly DUF2207 PF09972.9 PSC73430.1 - 0.32 9.7 1.4 2.3 6.9 0.5 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Gcd10p PF04189.13 PSC73431.1 - 1.9e-51 175.0 1.7 2.9e-51 174.4 0.0 1.9 2 0 0 2 2 1 1 Gcd10p family ABC_tran PF00005.27 PSC73431.1 - 1.7e-42 145.2 7.6 2e-21 76.9 0.0 3.4 3 0 0 3 3 2 2 ABC transporter ABC_tran_Xtn PF12848.7 PSC73431.1 - 4.4e-21 74.7 8.0 4.4e-21 74.7 8.0 3.4 3 0 0 3 3 1 1 ABC transporter rve PF00665.26 PSC73431.1 - 1.9e-18 66.7 0.0 5.7e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain AAA_21 PF13304.6 PSC73431.1 - 2e-15 57.4 4.0 0.00027 20.9 0.0 4.4 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PSC73431.1 - 3.6e-07 29.9 0.0 0.85 9.0 0.0 4.2 4 0 0 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PSC73431.1 - 9.1e-06 25.3 0.0 0.027 14.2 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 PSC73431.1 - 4.8e-05 23.2 0.0 0.43 10.2 0.0 3.7 4 0 0 4 4 4 1 AAA ATPase domain AAA_22 PF13401.6 PSC73431.1 - 0.00011 22.5 0.0 0.091 13.0 0.0 3.1 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 PSC73431.1 - 0.00024 21.1 0.0 0.17 11.8 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 PSC73431.1 - 0.00028 21.2 7.0 0.011 16.0 0.0 3.2 3 0 0 3 3 2 2 AAA domain MMR_HSR1 PF01926.23 PSC73431.1 - 0.0018 18.4 0.0 0.075 13.1 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_18 PF13238.6 PSC73431.1 - 0.015 15.9 0.6 7.5 7.1 0.0 3.7 5 0 0 5 5 3 0 AAA domain rve_3 PF13683.6 PSC73431.1 - 0.015 15.0 0.0 0.05 13.4 0.0 1.9 1 0 0 1 1 1 0 Integrase core domain AAA_14 PF13173.6 PSC73431.1 - 0.015 15.3 0.0 7.1 6.7 0.0 3.4 4 0 0 4 4 3 0 AAA domain AAA_23 PF13476.6 PSC73431.1 - 0.019 15.5 0.0 0.019 15.5 0.0 4.4 4 1 0 4 4 3 0 AAA domain AAA PF00004.29 PSC73431.1 - 0.022 15.2 0.0 7.3 7.0 0.0 3.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 PSC73431.1 - 0.022 14.5 0.0 1.8 8.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 PSC73431.1 - 0.031 14.7 0.0 11 6.5 0.0 2.6 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 PSC73431.1 - 0.078 12.9 1.4 6.5 6.6 0.1 2.9 3 0 0 3 3 2 0 NACHT domain Presenilin PF01080.17 PSC73431.1 - 0.1 11.3 3.6 0.16 10.7 3.6 1.3 1 0 0 1 1 1 0 Presenilin AAA_33 PF13671.6 PSC73431.1 - 0.13 12.5 4.8 1.8 8.7 0.0 3.5 4 0 0 4 4 3 0 AAA domain Rad17 PF03215.15 PSC73431.1 - 0.16 11.9 0.0 16 5.3 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_16 PF13191.6 PSC73431.1 - 0.79 10.1 0.0 0.79 10.1 0.0 4.4 6 0 0 6 6 4 0 AAA ATPase domain AAA_27 PF13514.6 PSC73431.1 - 0.96 9.0 0.0 0.96 9.0 0.0 3.8 3 1 0 4 4 3 0 AAA domain Methyltransf_22 PF13383.6 PSC73432.1 - 1.3e-20 74.0 0.0 2.7e-20 73.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_21 PF05050.12 PSC73432.1 - 7.2e-08 32.6 0.0 1e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase FkbM domain MscS_porin PF12795.7 PSC73433.1 - 0.0094 15.5 1.1 0.016 14.8 1.1 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain PsbP PF01789.16 PSC73435.1 - 3.4e-14 53.3 0.0 5.4e-14 52.6 0.0 1.3 1 0 0 1 1 1 1 PsbP S1 PF00575.23 PSC73436.1 - 0.001 19.4 0.0 0.0016 18.7 0.0 1.3 1 0 0 1 1 1 1 S1 RNA binding domain Amidohydro_1 PF01979.20 PSC73437.1 - 3.9e-54 184.2 0.0 6.2e-54 183.6 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 PSC73437.1 - 2.5e-15 56.9 0.5 4.4e-10 39.6 0.1 2.5 2 0 0 2 2 2 2 Amidohydrolase family FAD_binding_3 PF01494.19 PSC73437.1 - 3.5e-13 49.5 0.0 1.4e-06 27.9 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain DAGK_acc PF00609.19 PSC73438.1 - 2.9e-35 122.0 0.0 8.6e-35 120.4 0.0 1.8 2 0 0 2 2 2 1 Diacylglycerol kinase accessory domain PAP2 PF01569.21 PSC73438.1 - 1.4e-22 79.9 1.6 1.4e-22 79.9 1.6 2.0 1 1 1 2 2 2 1 PAP2 superfamily DAGK_cat PF00781.24 PSC73438.1 - 8.5e-20 70.7 0.0 1.9e-19 69.5 0.0 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain FAD_syn PF06574.12 PSC73439.1 - 6.4e-15 55.4 0.0 5.3e-09 36.2 0.0 2.4 2 0 0 2 2 2 2 FAD synthetase CTP_transf_like PF01467.26 PSC73439.1 - 0.032 14.4 0.0 0.18 12.0 0.0 2.0 2 0 0 2 2 2 0 Cytidylyltransferase-like HGTP_anticodon2 PF12745.7 PSC73439.1 - 1.3 8.5 3.1 1.8 8.0 3.1 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DnaJ_C PF01556.18 PSC73440.1 - 2.5e-34 118.5 0.0 3.6e-34 118.0 0.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PSC73440.1 - 8.8e-25 86.6 3.9 1.4e-24 86.0 3.9 1.3 1 0 0 1 1 1 1 DnaJ domain Sdh_cyt PF01127.22 PSC73440.1 - 6e-12 45.7 0.1 9.2e-12 45.1 0.1 1.3 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit RRM_1 PF00076.22 PSC73442.1 - 2e-27 94.8 0.0 6.4e-17 61.1 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PSC73442.1 - 0.00094 19.3 0.0 0.0019 18.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 PSC73442.1 - 0.001 18.7 0.0 0.0015 18.1 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PSC73442.1 - 0.0094 16.0 0.0 2.7 8.1 0.0 2.2 2 0 0 2 2 2 2 RNA binding motif GRP PF07172.11 PSC73442.1 - 0.013 16.2 43.7 0.013 16.2 43.7 2.2 2 0 0 2 2 2 0 Glycine rich protein family RRM_occluded PF16842.5 PSC73442.1 - 0.057 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Occluded RNA-recognition motif PAP2 PF01569.21 PSC73444.1 - 8.3e-18 64.5 0.5 8.3e-18 64.5 0.5 4.1 1 1 3 4 4 4 2 PAP2 superfamily DUF4719 PF15843.5 PSC73444.1 - 0.34 11.0 2.0 0.7 10.0 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) ANTH PF07651.16 PSC73445.1 - 1e-50 172.3 0.0 4.2e-50 170.3 0.0 1.8 1 1 0 1 1 1 1 ANTH domain ENTH PF01417.20 PSC73445.1 - 0.0019 18.2 0.1 0.0031 17.5 0.1 1.2 1 0 0 1 1 1 1 ENTH domain RRM_1 PF00076.22 PSC73447.1 - 3.8e-12 45.8 0.0 6.4e-12 45.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CutA1 PF03091.15 PSC73448.1 - 3.3e-34 116.7 0.0 5.2e-34 116.1 0.0 1.3 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein Sulfotransfer_2 PF03567.14 PSC73449.1 - 2.3e-09 37.5 0.0 4e-09 36.8 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Syja_N PF02383.18 PSC73450.1 - 1.4e-63 215.1 0.0 1.8e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain AA_kinase PF00696.28 PSC73451.1 - 1.7e-46 158.7 5.4 2.5e-46 158.3 5.4 1.2 1 0 0 1 1 1 1 Amino acid kinase family DUF5542 PF17696.1 PSC73453.1 - 0.26 11.5 0.2 0.32 11.1 0.2 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5542) Ank_2 PF12796.7 PSC73454.1 - 3.5e-24 85.2 0.1 1.3e-05 25.7 0.0 6.2 3 1 3 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC73454.1 - 1.7e-21 76.3 6.0 0.00072 20.1 0.0 8.1 6 1 3 9 9 9 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC73454.1 - 2.3e-16 59.6 7.6 1.3e-06 28.5 0.0 7.1 4 2 3 7 7 7 3 Ankyrin repeats (many copies) Ank PF00023.30 PSC73454.1 - 9.1e-15 54.4 18.1 0.0058 17.0 0.0 8.5 7 1 0 7 7 7 5 Ankyrin repeat Ank_3 PF13606.6 PSC73454.1 - 8.6e-13 47.2 7.4 0.71 10.6 0.0 9.0 10 0 0 10 10 10 5 Ankyrin repeat zf-CCCH PF00642.24 PSC73454.1 - 8.1e-07 28.8 1.5 8.1e-07 28.8 1.5 3.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PSC73454.1 - 4.2e-05 23.4 1.0 4.2e-05 23.4 1.0 3.9 3 0 0 3 3 3 1 Zinc finger domain Saccharop_dh_N PF04455.12 PSC73454.1 - 0.31 11.5 0.9 0.66 10.4 0.5 1.7 2 0 0 2 2 2 0 LOR/SDH bifunctional enzyme conserved region zf-CCCH_4 PF18044.1 PSC73454.1 - 1.2 9.0 7.5 0.31 10.9 1.9 3.2 2 0 0 2 2 2 0 CCCH-type zinc finger Mito_carr PF00153.27 PSC73455.1 - 2.6e-42 142.6 4.1 2.6e-16 59.3 0.1 3.9 3 0 0 3 3 3 3 Mitochondrial carrier protein Aldose_epim PF01263.20 PSC73455.1 - 7.6e-39 133.8 0.0 3.7e-37 128.2 0.0 2.1 2 0 0 2 2 2 2 Aldose 1-epimerase TFIIA PF03153.13 PSC73456.1 - 0.029 14.4 9.3 0.034 14.2 9.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 PSC73456.1 - 0.091 12.4 7.5 0.11 12.0 7.5 1.2 1 0 0 1 1 1 0 Spt20 family Suf PF05843.14 PSC73456.1 - 0.18 11.8 3.9 0.2 11.6 3.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) F-box-like PF12937.7 PSC73457.1 - 0.00024 20.9 0.3 0.00053 19.8 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PSC73457.1 - 0.0041 17.0 0.4 0.0077 16.1 0.4 1.4 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.11 PSC73457.1 - 0.059 13.9 0.0 0.096 13.2 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A CoaE PF01121.20 PSC73458.1 - 3e-40 137.8 0.0 3.5e-40 137.6 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase Glyoxalase_4 PF13669.6 PSC73460.1 - 3.8e-12 46.4 0.0 5.9e-12 45.8 0.0 1.3 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 PSC73460.1 - 0.0095 16.1 0.0 0.016 15.3 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain zf-CW PF07496.15 PSC73461.1 - 9.6e-10 38.3 3.0 3.6e-09 36.5 3.0 2.1 1 0 0 1 1 1 1 CW-type Zinc Finger PWWP PF00855.17 PSC73461.1 - 6.5e-05 23.3 0.0 0.00015 22.1 0.0 1.6 1 0 0 1 1 1 1 PWWP domain zf-HC5HC2H_2 PF13832.6 PSC73461.1 - 0.00083 19.5 0.6 0.0019 18.3 0.6 1.5 1 0 0 1 1 1 1 PHD-zinc-finger like domain PHD PF00628.29 PSC73461.1 - 0.0099 15.8 16.2 0.037 13.9 9.4 2.7 2 0 0 2 2 2 2 PHD-finger Glu-tRNAGln PF02686.15 PSC73462.1 - 1.8e-14 53.8 0.3 5.2e-14 52.3 0.1 1.8 2 0 0 2 2 2 1 Glu-tRNAGln amidotransferase C subunit EspA PF03433.13 PSC73462.1 - 0.22 11.3 0.0 0.29 10.9 0.0 1.1 1 0 0 1 1 1 0 EspA-like secreted protein Peptidase_M24 PF00557.24 PSC73465.1 - 1.3e-53 181.9 0.4 1.7e-53 181.5 0.4 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 PSC73465.1 - 5e-15 55.5 6.7 1.1e-14 54.5 6.7 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 PSC73465.1 - 0.00012 22.1 5.4 0.00036 20.6 5.4 1.9 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 PSC73465.1 - 0.00015 21.5 3.2 0.00038 20.3 3.2 1.7 1 0 0 1 1 1 1 HIT zinc finger Crust_neurohorm PF01147.17 PSC73465.1 - 0.046 13.6 0.6 0.094 12.6 0.6 1.4 1 0 0 1 1 1 0 Crustacean CHH/MIH/GIH neurohormone family GATase_5 PF13507.6 PSC73466.1 - 3.1e-106 354.2 0.0 4.4e-106 353.7 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 PSC73466.1 - 6.5e-36 123.8 8.3 1.2e-19 71.0 0.1 2.4 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 PSC73466.1 - 2.9e-19 69.2 0.0 5.8e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 PSC73466.1 - 4.8e-11 43.0 0.1 1.1e-10 41.9 0.1 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 PSC73466.1 - 0.0035 18.0 3.4 0.0055 17.3 0.0 2.8 3 0 0 3 3 3 1 AIR synthase related protein, N-terminal domain NOT2_3_5 PF04153.18 PSC73467.1 - 1.1e-31 109.7 0.7 1.4e-31 109.2 0.7 1.2 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family ACT_3 PF10000.9 PSC73468.1 - 0.1 12.5 0.6 0.25 11.3 0.1 1.8 2 0 0 2 2 2 0 ACT domain DUF755 PF05501.11 PSC73468.1 - 0.3 11.3 22.0 0.67 10.2 22.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF755) GREB1 PF15782.5 PSC73468.1 - 9 3.3 8.2 12 2.8 8.2 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Lysine_decarbox PF03641.14 PSC73469.1 - 3.5e-38 130.7 0.1 1.6e-37 128.6 0.1 2.0 2 0 0 2 2 2 1 Possible lysine decarboxylase MS_channel PF00924.18 PSC73469.1 - 2.9e-13 49.9 0.7 5.1e-13 49.1 0.7 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel LDcluster4 PF18306.1 PSC73469.1 - 9.2e-11 41.6 1.8 9.2e-11 41.6 1.8 1.6 2 0 0 2 2 2 1 SLOG cluster4 family TPR_12 PF13424.6 PSC73470.1 - 2e-06 28.0 4.1 2e-06 28.0 4.1 4.9 4 1 0 5 5 5 1 Tetratricopeptide repeat SATase_N PF06426.14 PSC73471.1 - 2.7e-39 133.7 0.6 4.7e-39 133.0 0.6 1.4 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 PSC73471.1 - 3.9e-10 39.0 3.4 2.5e-06 27.0 0.1 2.3 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 PSC73471.1 - 3.6e-07 29.8 4.2 6.4e-05 22.6 0.5 2.3 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase Bactofilin PF04519.13 PSC73471.1 - 0.04 14.2 1.1 0.072 13.4 1.1 1.4 1 0 0 1 1 1 0 Polymer-forming cytoskeletal adh_short PF00106.25 PSC73472.1 - 1.1e-25 90.3 0.3 1.4e-24 86.7 0.3 2.2 1 1 0 1 1 1 1 short chain dehydrogenase rve PF00665.26 PSC73472.1 - 1.4e-18 67.3 0.0 3.2e-18 66.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain adh_short_C2 PF13561.6 PSC73472.1 - 5.9e-13 48.9 0.3 1.7e-12 47.4 0.3 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC73472.1 - 4e-10 39.9 1.4 9.7e-10 38.6 1.4 1.6 1 0 0 1 1 1 1 KR domain rve_3 PF13683.6 PSC73472.1 - 0.0094 15.7 0.0 0.031 14.1 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain Epimerase PF01370.21 PSC73472.1 - 0.11 12.0 0.2 0.41 10.0 0.2 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family zf-C3HC4 PF00097.25 PSC73474.1 - 2.5e-07 30.5 2.4 2.5e-07 30.5 2.4 2.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC73474.1 - 1.2e-06 28.7 4.2 1.2e-06 28.7 4.2 3.2 3 0 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 PSC73474.1 - 1.8e-06 27.8 2.3 1.8e-06 27.8 2.3 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 PSC73474.1 - 4.6e-05 23.6 2.7 4.6e-05 23.6 2.7 2.7 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 PSC73474.1 - 0.00078 19.5 1.1 0.00078 19.5 1.1 2.8 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 PSC73474.1 - 0.0011 18.9 0.5 0.0011 18.9 0.5 2.3 2 0 0 2 2 2 1 RING-type zinc-finger zf-CCCH PF00642.24 PSC73474.1 - 0.0017 18.2 0.8 0.0017 18.2 0.8 2.5 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_3 PF13920.6 PSC73474.1 - 0.0048 16.7 2.7 0.0048 16.7 2.7 2.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PSC73474.1 - 0.96 9.4 10.2 0.32 10.9 3.5 2.9 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 Cys_rich_CPXG PF14255.6 PSC73474.1 - 1.1 9.2 8.3 1.7 8.6 0.4 2.8 3 0 0 3 3 3 0 Cysteine-rich CPXCG zf-ANAPC11 PF12861.7 PSC73474.1 - 3.8 7.6 17.9 0.11 12.6 3.9 3.0 1 1 2 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger Torus PF16131.5 PSC73474.1 - 6.3 7.6 10.8 4.1 8.1 0.1 2.8 3 0 0 3 3 2 0 Torus domain CRCB PF02537.15 PSC73475.1 - 6e-29 100.2 18.4 6.5e-18 64.8 6.9 2.6 2 0 0 2 2 2 2 CrcB-like protein, Camphor Resistance (CrcB) Pro_CA PF00484.19 PSC73476.1 - 3.2e-47 160.7 0.0 5.3e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase SMC_N PF02463.19 PSC73477.1 - 2e-41 141.8 0.0 2.8e-41 141.4 0.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain PseudoU_synth_2 PF00849.22 PSC73477.1 - 3.3e-24 85.8 0.4 1.3e-22 80.6 0.0 2.8 3 0 0 3 3 3 1 RNA pseudouridylate synthase AAA_21 PF13304.6 PSC73477.1 - 3.7e-12 46.7 0.0 1.5e-06 28.2 0.0 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 PSC73477.1 - 1.7e-06 28.7 0.0 1.7e-06 28.7 0.0 4.3 2 2 2 4 4 4 1 AAA domain S4 PF01479.25 PSC73477.1 - 0.00063 19.4 0.0 0.014 15.1 0.0 2.7 2 0 0 2 2 2 1 S4 domain YkyA PF10368.9 PSC73477.1 - 0.0016 18.2 11.8 0.0016 18.2 11.8 3.5 5 0 0 5 5 5 1 Putative cell-wall binding lipoprotein AAA_15 PF13175.6 PSC73477.1 - 0.051 13.3 0.1 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 PSC73477.1 - 0.13 12.7 0.1 0.52 10.7 0.1 2.1 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 PSC73477.1 - 4.6 7.8 14.8 0.89 10.1 0.0 4.2 5 0 0 5 5 5 0 ABC transporter V-SNARE_C PF12352.8 PSC73478.1 - 5.1e-15 55.5 0.2 5.1e-15 55.5 0.2 2.2 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 PSC73478.1 - 0.00016 21.5 0.4 0.00061 19.7 0.0 2.1 2 1 0 2 2 2 1 Sec20 BssS PF13991.6 PSC73478.1 - 0.067 13.3 0.2 0.19 11.8 0.2 1.7 1 0 0 1 1 1 0 BssS protein family TMA7 PF09072.10 PSC73478.1 - 0.12 13.2 0.4 0.33 11.8 0.4 1.7 1 0 0 1 1 1 0 Translation machinery associated TMA7 CoA_binding_2 PF13380.6 PSC73479.1 - 1.3e-09 38.6 0.0 1.4e-09 38.5 0.0 1.0 1 0 0 1 1 1 1 CoA binding domain FAD_binding_4 PF01565.23 PSC73479.1 - 0.072 12.8 0.0 0.072 12.8 0.0 1.1 1 0 0 1 1 1 0 FAD binding domain Nup35_RRM PF05172.13 PSC73480.1 - 3.9e-15 55.6 0.0 1.2e-14 54.1 0.0 1.7 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 PSC73480.1 - 0.0002 21.3 0.0 0.00029 20.8 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DNA_primase_S PF01896.19 PSC73481.1 - 6.9e-53 179.3 0.1 8.9e-53 178.9 0.1 1.1 1 0 0 1 1 1 1 DNA primase small subunit DUF2710 PF10921.8 PSC73481.1 - 0.011 16.2 0.1 0.026 14.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2710) DUF469 PF04320.14 PSC73481.1 - 0.041 14.8 0.1 0.98 10.3 0.0 2.8 2 1 0 3 3 3 0 Protein with unknown function (DUF469) BP28CT PF08146.12 PSC73482.1 - 5.6e-35 120.5 0.0 1.7e-34 119.0 0.0 1.9 2 0 0 2 2 2 1 BP28CT (NUC211) domain U3snoRNP10 PF12397.8 PSC73482.1 - 7.8e-20 71.4 0.2 7.8e-20 71.4 0.2 4.6 4 0 0 4 4 4 1 U3 small nucleolar RNA-associated protein 10 KNOX1 PF03790.13 PSC73482.1 - 0.11 12.2 0.7 0.76 9.5 0.7 2.5 1 0 0 1 1 1 0 KNOX1 domain MOFRL PF05161.13 PSC73482.1 - 0.29 11.4 3.3 87 3.4 3.2 3.7 2 0 0 2 2 2 0 MOFRL family Popeye PF04831.13 PSC73483.1 - 0.93 9.7 5.6 12 6.1 0.0 2.3 2 1 0 2 2 2 0 Popeye protein conserved region Sec23_trunk PF04811.15 PSC73484.1 - 6.1e-10 39.1 0.0 0.0015 18.2 0.0 3.4 3 0 0 3 3 3 3 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 PSC73484.1 - 7.3e-09 35.5 2.4 1.2e-08 34.9 2.4 1.3 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.15 PSC73484.1 - 9.2e-08 31.8 0.0 1.9e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain VWA_3 PF13768.6 PSC73484.1 - 0.00017 21.5 0.0 0.027 14.4 0.0 2.8 2 0 0 2 2 2 1 von Willebrand factor type A domain Sec23_BS PF08033.12 PSC73484.1 - 0.0071 17.1 0.0 0.041 14.6 0.0 2.0 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Cu-oxidase_4 PF02578.15 PSC73485.1 - 0.053 13.1 0.0 0.068 12.8 0.0 1.1 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase Arch_flagellin PF01917.16 PSC73486.1 - 0.22 11.7 0.2 0.3 11.2 0.2 1.1 1 0 0 1 1 1 0 Archaebacterial flagellin Tubulin PF00091.25 PSC73487.1 - 1.1e-67 228.1 0.0 1.7e-67 227.5 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PSC73487.1 - 1.2e-41 141.9 0.1 1.7e-41 141.3 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 PSC73487.1 - 0.0004 20.7 0.0 0.0011 19.3 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 PSC73487.1 - 0.0033 16.7 0.1 0.011 14.9 0.0 1.8 2 0 0 2 2 2 1 Tubulin like Tubulin_3 PF14881.6 PSC73487.1 - 0.0035 17.1 0.0 0.0063 16.2 0.0 1.4 1 0 0 1 1 1 1 Tubulin domain Clathrin PF00637.20 PSC73488.1 - 2.1e-194 637.2 32.5 9.4e-32 109.9 1.0 8.0 8 0 0 8 8 8 7 Region in Clathrin and VPS Clathrin_H_link PF13838.6 PSC73488.1 - 1.4e-30 105.0 2.3 1.8e-29 101.4 0.1 3.9 4 0 0 4 4 4 1 Clathrin-H-link Clathrin_propel PF01394.20 PSC73488.1 - 1.5e-25 88.2 0.0 5.4e-07 29.6 0.0 6.5 6 0 0 6 6 6 4 Clathrin propeller repeat Coatomer_WDAD PF04053.14 PSC73488.1 - 3.6e-08 32.9 1.0 0.0031 16.6 0.0 3.1 3 0 0 3 3 3 2 Coatomer WD associated region Clathrin-link PF09268.10 PSC73488.1 - 3.5e-07 29.5 0.0 9.5e-07 28.1 0.0 1.8 1 0 0 1 1 1 1 Clathrin, heavy-chain linker Vps8 PF12816.7 PSC73488.1 - 1.9e-05 24.3 0.7 0.038 13.5 0.1 3.8 3 0 0 3 3 3 2 Golgi CORVET complex core vacuolar protein 8 TPR_1 PF00515.28 PSC73488.1 - 0.0061 16.3 0.6 13 5.8 0.0 5.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PSC73488.1 - 0.061 14.2 29.4 13 6.9 0.1 11.3 9 3 4 13 13 13 0 Tetratricopeptide repeat TPR_7 PF13176.6 PSC73488.1 - 4 7.7 11.9 13 6.1 0.0 5.7 6 1 0 6 6 6 0 Tetratricopeptide repeat TPR_4 PF07721.14 PSC73488.1 - 6 7.8 7.7 3.4 8.6 0.3 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat WD40 PF00400.32 PSC73489.1 - 5.1e-07 30.3 3.7 0.00081 20.2 0.1 4.0 5 0 0 5 5 5 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 PSC73489.1 - 0.026 14.6 0.0 0.52 10.4 0.0 2.2 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, middle region NifQ PF04891.12 PSC73490.1 - 0.086 13.2 0.1 0.26 11.6 0.1 1.7 1 0 0 1 1 1 0 NifQ RelB_transactiv PF16181.5 PSC73490.1 - 0.16 12.2 5.1 0.37 11.0 2.6 2.4 2 0 0 2 2 2 0 RelB transactivation domain Sorting_nexin PF03700.13 PSC73491.1 - 0.32 11.5 3.6 0.29 11.7 1.8 1.8 2 1 0 2 2 2 0 Sorting nexin, N-terminal domain PSI_PsaE PF02427.17 PSC73492.1 - 2e-32 110.6 0.9 2.6e-32 110.3 0.9 1.1 1 0 0 1 1 1 1 Photosystem I reaction centre subunit IV / PsaE STAS PF01740.21 PSC73493.1 - 2.2e-21 75.7 0.0 2.6e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 PSC73493.1 - 8.3e-08 32.5 3.3 1.6e-07 31.5 3.3 1.5 1 0 0 1 1 1 1 STAS domain Glyco_transf_92 PF01697.27 PSC73494.1 - 1.9e-05 24.4 0.0 2.8e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 PDZ PF00595.24 PSC73495.1 - 0.0002 21.6 0.0 0.00033 20.9 0.0 1.3 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PSC73495.1 - 0.037 13.9 0.0 0.085 12.7 0.0 1.6 1 0 0 1 1 1 0 PDZ domain KDZ PF18758.1 PSC73496.1 - 1.7e-09 37.7 0.9 1.1e-06 28.5 0.0 2.4 1 1 1 2 2 2 2 Kyakuja-Dileera-Zisupton transposase SpoU_methylase PF00588.19 PSC73497.1 - 1.3e-22 80.5 0.0 3.6e-22 79.1 0.0 1.7 1 1 0 1 1 1 1 SpoU rRNA Methylase family AP_endonuc_2 PF01261.24 PSC73497.1 - 0.11 11.9 0.2 0.16 11.4 0.2 1.2 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel NFACT-R_1 PF05670.13 PSC73498.1 - 2.2e-39 134.5 0.0 3.8e-39 133.7 0.0 1.4 1 0 0 1 1 1 1 NFACT protein RNA binding domain Auts2 PF15336.6 PSC73498.1 - 0.02 15.0 0.7 0.027 14.6 0.7 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein RVT_1 PF00078.27 PSC73499.1 - 4e-82 275.0 0.0 3e-27 95.6 0.0 5.0 3 2 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) Ribosomal_L2_C PF03947.18 PSC73499.1 - 4.9e-50 169.0 4.1 7e-50 168.4 2.9 2.0 2 0 0 2 2 2 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 PSC73499.1 - 1e-21 76.6 0.1 2.3e-21 75.5 0.1 1.6 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain LamB_YcsF PF03746.16 PSC73499.1 - 0.00011 21.9 4.1 4.2 7.0 0.1 3.6 3 0 0 3 3 3 3 LamB/YcsF family DUF2857 PF11198.8 PSC73499.1 - 0.0013 18.6 3.6 12 5.7 0.1 3.8 3 0 0 3 3 3 3 Protein of unknown function (DUF2857) BLM10_N PF16547.5 PSC73499.1 - 0.42 10.9 2.4 1.6e+02 2.7 0.1 3.5 3 0 0 3 3 3 0 Proteasome-substrate-size regulator, N-terminal CDKN3 PF05706.12 PSC73500.1 - 4.3e-06 26.5 0.0 8.3e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Sulfotransfer_2 PF03567.14 PSC73500.1 - 0.00081 19.4 0.7 0.014 15.3 0.1 2.6 3 0 0 3 3 3 1 Sulfotransferase family DSPc PF00782.20 PSC73500.1 - 0.0082 16.0 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 PSC73500.1 - 0.17 11.8 0.0 0.55 10.2 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family CDKN3 PF05706.12 PSC73501.1 - 4.4e-06 26.5 0.0 8.5e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Sulfotransfer_2 PF03567.14 PSC73501.1 - 0.00095 19.1 0.7 0.014 15.3 0.1 2.5 3 0 0 3 3 3 1 Sulfotransferase family DSPc PF00782.20 PSC73501.1 - 0.016 15.0 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Rieske PF00355.26 PSC73502.1 - 4.4e-12 45.8 0.1 1.2e-11 44.3 0.1 1.7 1 1 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 PSC73502.1 - 1.3e-10 41.6 0.5 3.7e-10 40.1 0.4 1.9 1 1 1 2 2 2 1 Ubiquinol cytochrome reductase transmembrane region Snf7 PF03357.21 PSC73503.1 - 1.8e-29 102.5 21.3 3.7e-29 101.5 21.3 1.6 1 1 0 1 1 1 1 Snf7 Sin3a_C PF16879.5 PSC73503.1 - 0.037 13.7 1.8 0.042 13.6 0.6 1.7 1 1 1 2 2 2 0 C-terminal domain of Sin3a protein vWA-TerF-like PF10138.9 PSC73503.1 - 0.12 12.5 0.2 0.17 12.0 0.2 1.3 1 0 0 1 1 1 0 vWA found in TerF C terminus GvpK PF05121.12 PSC73503.1 - 9.2 6.4 14.8 0.21 11.6 3.7 3.0 3 0 0 3 3 3 0 Gas vesicle protein K Telomerase_RBD PF12009.8 PSC73504.1 - 2.7e-36 124.6 0.0 4.7e-36 123.9 0.0 1.4 1 0 0 1 1 1 1 Telomerase ribonucleoprotein complex - RNA binding domain RVT_1 PF00078.27 PSC73504.1 - 4.8e-05 23.0 0.0 0.57 9.7 0.0 3.3 3 0 0 3 3 3 3 Reverse transcriptase (RNA-dependent DNA polymerase) AstE_AspA PF04952.14 PSC73505.1 - 0.029 13.5 0.5 0.041 13.0 0.5 1.2 1 0 0 1 1 1 0 Succinylglutamate desuccinylase / Aspartoacylase family DUF3525 PF12039.8 PSC73506.1 - 0.08 11.7 0.0 0.11 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3525) TFA2_Winged_2 PF18121.1 PSC73507.1 - 7.8e-08 31.9 0.0 1.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 TFA2 Winged helix domain 2 DUF3886 PF13025.6 PSC73507.1 - 0.61 10.3 7.1 1.2 9.4 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3886) Nup54 PF13874.6 PSC73508.1 - 4.9e-27 94.7 0.6 7.7e-27 94.1 0.6 1.3 1 0 0 1 1 1 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 PSC73508.1 - 2.7e-05 24.9 34.4 5e-05 24.1 19.2 2.8 1 1 1 2 2 2 2 Nucleoporin FG repeat region Ntox1 PF15500.6 PSC73508.1 - 0.029 14.7 0.3 0.058 13.7 0.3 1.4 1 0 0 1 1 1 0 Putative RNase-like toxin, toxin_1 FPN1 PF06963.12 PSC73509.1 - 1.3e-93 313.9 13.0 6e-76 255.8 7.9 2.1 2 0 0 2 2 2 2 Ferroportin1 (FPN1) Cpn10 PF00166.21 PSC73509.1 - 1.4e-42 143.6 0.2 2.7e-21 75.4 0.0 3.3 3 0 0 3 3 3 3 Chaperonin 10 Kd subunit Toxin_GhoT_OrtT PF10753.9 PSC73509.1 - 0.00036 20.7 0.1 2 8.7 0.0 2.8 2 0 0 2 2 2 2 Toxin GhoT_OrtT DUF3331 PF11811.8 PSC73509.1 - 0.12 12.2 0.4 31 4.5 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3331) Flavi_NS4A PF01350.17 PSC73509.1 - 0.26 11.2 0.1 0.26 11.2 0.1 2.8 3 0 0 3 3 3 0 Flavivirus non-structural protein NS4A Kinocilin PF15033.6 PSC73509.1 - 9.3 5.9 11.7 16 5.2 1.9 2.8 2 0 0 2 2 2 0 Kinocilin protein PFK PF00365.20 PSC73510.1 - 5e-58 196.7 0.6 6.1e-58 196.4 0.6 1.1 1 0 0 1 1 1 1 Phosphofructokinase MoCF_biosynth PF00994.24 PSC73510.1 - 0.09 12.4 0.1 0.25 11.0 0.0 1.7 1 1 1 2 2 2 0 Probable molybdopterin binding domain Caldesmon PF02029.15 PSC73511.1 - 1.6 7.4 55.5 2.7 6.7 55.5 1.4 1 0 0 1 1 1 0 Caldesmon Abhydrolase_6 PF12697.7 PSC73512.1 - 1.5e-13 51.9 9.5 1.5e-13 51.9 9.5 1.6 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PSC73512.1 - 2e-13 50.6 0.0 8e-09 35.5 0.1 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC73512.1 - 3.3e-09 36.4 0.2 1.5e-07 30.9 0.2 2.2 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 PSC73512.1 - 0.00042 19.9 0.0 0.00078 19.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 PSC73512.1 - 0.004 16.7 0.0 0.0077 15.8 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family LIP PF03583.14 PSC73512.1 - 0.0099 15.2 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Secretory lipase Abhydrolase_4 PF08386.10 PSC73512.1 - 0.066 13.3 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.13 PSC73512.1 - 0.13 11.9 0.0 0.19 11.3 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_2 PF02230.16 PSC73512.1 - 0.16 11.8 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase Rieske PF00355.26 PSC73513.1 - 3.8e-18 65.2 0.0 8.1e-18 64.2 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain DUF5437 PF17505.2 PSC73514.1 - 0.33 11.0 3.3 0.58 10.2 1.7 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5437) PAN_4 PF14295.6 PSC73515.1 - 3.6e-05 23.6 2.3 3.6e-05 23.6 2.3 2.6 2 0 0 2 2 2 1 PAN domain PAN_1 PF00024.26 PSC73515.1 - 0.00035 20.5 0.3 0.00035 20.5 0.3 1.8 2 0 0 2 2 2 1 PAN domain Arm PF00514.23 PSC73516.1 - 3e-11 43.0 36.5 0.12 12.4 0.7 8.4 9 0 0 9 9 9 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 PSC73516.1 - 1.7e-05 25.2 49.2 3.5e-05 24.2 1.5 8.4 5 1 2 7 7 7 4 HEAT-like repeat HEAT PF02985.22 PSC73516.1 - 3.8e-05 23.6 15.8 0.026 14.7 0.0 7.6 7 0 0 7 7 7 1 HEAT repeat RICTOR_V PF14668.6 PSC73516.1 - 0.034 14.4 0.2 19 5.6 0.0 3.0 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 Cnd1 PF12717.7 PSC73516.1 - 0.073 13.1 0.0 8.3 6.4 0.1 3.2 3 0 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 TFIIA PF03153.13 PSC73517.1 - 1.4e-44 153.8 19.1 4.6e-31 109.2 16.5 3.0 2 1 1 3 3 3 2 Transcription factor IIA, alpha/beta subunit DUF2967 PF11179.8 PSC73517.1 - 0.032 12.3 6.6 0.091 10.8 6.6 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Clr2 PF10383.9 PSC73517.1 - 0.068 13.9 0.8 0.18 12.6 0.8 1.8 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 EPL1 PF10513.9 PSC73517.1 - 4.3 7.7 7.0 4.4 7.7 4.1 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like FTZ PF03867.14 PSC73517.1 - 5.8 6.4 10.8 10 5.6 10.8 1.3 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region RRM_2 PF04059.12 PSC73518.1 - 1e-44 150.7 0.1 1.5e-44 150.1 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 PSC73518.1 - 2.7e-21 75.2 0.0 1.4e-10 40.9 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PSC73518.1 - 0.00022 20.8 0.0 1 8.9 0.0 2.8 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ADH_zinc_N PF00107.26 PSC73519.1 - 7.4e-18 64.8 0.3 1.6e-17 63.7 0.3 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PSC73519.1 - 7.7e-12 46.4 0.1 2.6e-11 44.7 0.1 2.0 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PSC73519.1 - 3.9e-06 26.7 0.0 1.8e-05 24.6 0.0 2.0 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ERO1 PF04137.15 PSC73520.1 - 4.4e-113 378.1 0.0 5.2e-113 377.8 0.0 1.0 1 0 0 1 1 1 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) PDT PF00800.18 PSC73521.1 - 1.6e-55 187.8 0.8 4.7e-55 186.2 0.0 2.1 2 0 0 2 2 2 1 Prephenate dehydratase PsbP PF01789.16 PSC73521.1 - 5.8e-32 111.0 0.0 1.1e-31 110.1 0.0 1.4 1 0 0 1 1 1 1 PsbP PWWP PF00855.17 PSC73521.1 - 5e-16 58.9 1.5 1.1e-15 57.8 1.5 1.5 1 0 0 1 1 1 1 PWWP domain ACT PF01842.25 PSC73521.1 - 0.0012 18.6 0.0 0.0025 17.6 0.0 1.5 1 0 0 1 1 1 1 ACT domain Abhydrolase_1 PF00561.20 PSC73522.1 - 4.2e-15 56.1 0.2 7e-15 55.4 0.2 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC73522.1 - 1.2e-11 44.4 0.3 2.3e-11 43.4 0.3 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PSC73522.1 - 1.3e-06 29.1 48.4 1.4e-05 25.8 21.5 2.6 2 1 1 3 3 3 2 Alpha/beta hydrolase family Methyltransf_12 PF08242.12 PSC73524.1 - 3.3e-06 27.8 0.0 6.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC73524.1 - 0.00017 22.2 0.0 0.00033 21.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC73524.1 - 0.0048 16.8 0.0 0.0068 16.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_33 PF10017.9 PSC73524.1 - 0.0048 16.1 0.0 0.01 15.0 0.0 1.5 1 1 0 1 1 1 1 Histidine-specific methyltransferase, SAM-dependent Methyltransf_31 PF13847.6 PSC73524.1 - 0.0062 16.3 0.0 0.0092 15.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Cytochrome_P460 PF16694.5 PSC73524.1 - 0.02 15.2 0.0 0.029 14.7 0.0 1.3 1 0 0 1 1 1 0 Cytochrome P460 Sulfotransfer_2 PF03567.14 PSC73525.1 - 0.0012 18.8 0.3 0.0021 18.0 0.3 1.4 1 0 0 1 1 1 1 Sulfotransferase family GntR PF00392.21 PSC73525.1 - 0.055 13.1 0.1 1.8 8.3 0.0 2.8 2 0 0 2 2 2 0 Bacterial regulatory proteins, gntR family DUF3082 PF11282.8 PSC73526.1 - 1.2e-23 83.1 3.9 1.2e-23 83.1 3.9 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF3082) Glyco_transf_6 PF03414.13 PSC73526.1 - 0.23 10.2 0.0 0.31 9.8 0.0 1.1 1 0 0 1 1 1 0 Glycosyltransferase family 6 O-FucT PF10250.9 PSC73527.1 - 4.7e-09 36.4 0.0 1.5e-08 34.8 0.0 1.8 2 0 0 2 2 2 1 GDP-fucose protein O-fucosyltransferase VTC PF09359.10 PSC73528.1 - 4.6e-70 236.2 0.0 7.2e-70 235.5 0.0 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 PSC73528.1 - 2.2e-20 74.0 13.6 5.2e-10 39.8 0.8 3.3 2 1 1 3 3 3 3 SPX domain DUF202 PF02656.15 PSC73528.1 - 6.6e-13 48.9 2.5 6.6e-13 48.9 2.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) CCDC154 PF15450.6 PSC73528.1 - 0.087 11.4 2.6 0.15 10.6 2.6 1.2 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 154 DUF1700 PF08006.11 PSC73528.1 - 0.87 9.1 3.6 5.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) VTC PF09359.10 PSC73529.1 - 4.1e-70 236.3 0.0 6.5e-70 235.7 0.0 1.3 1 0 0 1 1 1 1 VTC domain SPX PF03105.19 PSC73529.1 - 2.1e-20 74.0 13.6 5.2e-10 39.8 0.8 3.3 2 1 1 3 3 3 3 SPX domain DUF202 PF02656.15 PSC73529.1 - 6.6e-13 48.9 2.5 6.6e-13 48.9 2.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DEAD PF00270.29 PSC73530.1 - 4.3e-16 59.2 0.0 4.3e-16 59.2 0.0 1.9 2 0 0 2 2 1 1 DEAD/DEAH box helicase RQC PF09382.10 PSC73530.1 - 7.9e-16 57.9 0.0 2.3e-15 56.4 0.0 1.7 2 0 0 2 2 2 1 RQC domain RecQ_Zn_bind PF16124.5 PSC73530.1 - 8.4e-15 55.3 7.8 8.4e-15 55.3 7.8 3.0 2 0 0 2 2 1 1 RecQ zinc-binding Helicase_C PF00271.31 PSC73530.1 - 2.1e-13 50.6 0.0 6.2e-13 49.1 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC73530.1 - 0.0059 16.6 0.5 0.027 14.5 0.0 2.2 2 1 0 2 2 1 1 Type III restriction enzyme, res subunit SpoIIP PF07454.11 PSC73530.1 - 1.2 8.6 9.9 2 7.8 9.9 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 PSC73530.1 - 2 7.1 12.5 3.4 6.3 12.5 1.3 1 0 0 1 1 1 0 Presenilin Band_3_cyto PF07565.13 PSC73530.1 - 3 7.6 8.2 9.8 5.9 8.2 1.9 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4407 PF14362.6 PSC73530.1 - 3.2 7.0 14.1 5.8 6.2 9.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PBP1_TM PF14812.6 PSC73530.1 - 6.7 7.2 13.2 26 5.3 0.0 3.7 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal eIF3_subunit PF08597.10 PSC73530.1 - 7.4 6.4 12.5 0.42 10.5 6.3 2.1 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit PCI PF01399.27 PSC73531.1 - 1.1e-07 32.3 0.0 2.1e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 PCI domain Branch PF02485.21 PSC73532.1 - 8.6e-37 127.0 0.1 1.3e-36 126.3 0.1 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme DUF3337 PF11816.8 PSC73533.1 - 8.4e-25 87.6 0.0 1.6e-24 86.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3337) WD40 PF00400.32 PSC73533.1 - 1.8e-24 85.5 12.6 1.2e-07 32.2 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC73533.1 - 1.4e-06 28.5 0.3 0.025 14.8 0.0 4.6 1 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PSC73533.1 - 0.0015 18.0 0.0 0.0025 17.2 0.0 1.3 1 0 0 1 1 1 1 WD40-like domain Nucleoporin_N PF08801.11 PSC73533.1 - 0.047 12.4 0.0 0.93 8.2 0.0 2.7 2 1 1 3 3 3 0 Nup133 N terminal like Nup160 PF11715.8 PSC73533.1 - 0.13 10.9 0.5 1.3 7.5 0.1 2.6 2 1 0 3 3 3 0 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 PSC73533.1 - 0.13 11.1 0.1 0.25 10.2 0.1 1.4 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain Activator_LAG-3 PF11498.8 PSC73534.1 - 0.038 13.0 34.5 0.059 12.3 34.5 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TFIIA PF03153.13 PSC73534.1 - 0.19 11.7 17.2 0.31 11.0 17.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YjbH PF06082.11 PSC73534.1 - 0.72 8.6 3.8 1 8.1 3.8 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH SARAF PF06682.12 PSC73534.1 - 2 8.0 7.5 0.19 11.3 1.2 2.2 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Asp PF00026.23 PSC73535.1 - 2e-115 385.5 0.0 2.8e-115 385.1 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 PSC73535.1 - 2.6e-13 50.6 0.0 7.8e-12 45.8 0.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal SapB_1 PF05184.15 PSC73535.1 - 3.2e-10 39.8 0.5 6.6e-10 38.8 0.5 1.6 1 0 0 1 1 1 1 Saposin-like type B, region 1 SapB_2 PF03489.17 PSC73535.1 - 1e-09 38.3 3.7 1e-09 38.3 3.7 2.4 3 0 0 3 3 3 1 Saposin-like type B, region 2 Asp_protease_2 PF13650.6 PSC73535.1 - 0.0036 17.9 0.0 4 8.2 0.0 3.4 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 PSC73535.1 - 0.0092 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Glyco_transf_25 PF01755.17 PSC73536.1 - 3.9e-15 56.2 0.0 1.5e-13 51.1 0.0 2.1 1 1 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) PROCN PF08083.11 PSC73537.1 - 1.6e-234 778.1 8.0 2.4e-234 777.4 8.0 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 PSC73537.1 - 8.9e-127 421.4 0.4 1.4e-126 420.7 0.4 1.3 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 PSC73537.1 - 4.8e-89 296.4 2.5 3.1e-88 293.7 2.1 2.5 2 0 0 2 2 2 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 PSC73537.1 - 2e-82 274.6 3.6 2e-82 274.6 3.6 1.9 2 0 0 2 2 2 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 PSC73537.1 - 6.4e-73 243.1 0.0 1.3e-72 242.2 0.0 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 PSC73537.1 - 7.7e-51 171.2 0.0 1.9e-50 169.9 0.0 1.7 1 0 0 1 1 1 1 PROCT (NUC072) domain RRM_4 PF10598.9 PSC73537.1 - 1e-45 154.0 0.2 2.9e-45 152.5 0.2 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 PSC73537.1 - 1.3e-06 28.4 0.0 3.2e-06 27.1 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PUB PF09409.10 PSC73538.1 - 3.7e-12 46.0 0.0 5.6e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 PUB domain Tombus_P33 PF08500.10 PSC73538.1 - 0.03 14.3 2.5 0.049 13.6 2.5 1.2 1 0 0 1 1 1 0 Tombusvirus p33 RBD PF02196.15 PSC73538.1 - 0.058 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 Raf-like Ras-binding domain POT1 PF02765.17 PSC73539.1 - 8.1e-20 71.1 0.0 1.4e-19 70.3 0.0 1.4 1 0 0 1 1 1 1 Telomeric single stranded DNA binding POT1/CDC13 DUF202 PF02656.15 PSC73539.1 - 8.1e-11 42.2 1.9 8.1e-11 42.2 1.9 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF202) POT1PC PF16686.5 PSC73539.1 - 3.3e-06 27.1 0.0 0.00042 20.2 0.0 3.0 3 0 0 3 3 3 1 ssDNA-binding domain of telomere protection protein HMG_box_2 PF09011.10 PSC73540.1 - 7.5e-05 23.2 0.7 0.00012 22.6 0.7 1.3 1 0 0 1 1 1 1 HMG-box domain HMG_box PF00505.19 PSC73540.1 - 0.00063 20.1 0.2 0.0011 19.3 0.2 1.4 1 0 0 1 1 1 1 HMG (high mobility group) box SBF_like PF13593.6 PSC73541.1 - 6.8e-38 130.7 16.7 6.8e-38 130.7 16.7 1.7 2 0 0 2 2 2 1 SBF-like CPA transporter family (DUF4137) Ion_trans_2 PF07885.16 PSC73541.1 - 5.4e-12 45.5 0.2 5.4e-12 45.5 0.2 2.9 3 1 1 4 4 4 1 Ion channel Ion_trans PF00520.31 PSC73541.1 - 4.8e-10 39.1 4.6 4.8e-10 39.1 4.6 2.1 3 0 0 3 3 3 1 Ion transport protein SBF PF01758.16 PSC73541.1 - 3.3e-09 36.7 3.6 3.3e-09 36.7 3.6 3.0 3 1 1 4 4 4 1 Sodium Bile acid symporter family cNMP_binding PF00027.29 PSC73541.1 - 6.4e-09 35.8 0.0 1.4e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Mem_trans PF03547.18 PSC73541.1 - 0.5 8.7 7.6 0.072 11.5 0.6 2.3 2 0 0 2 2 2 0 Membrane transport protein RRM_1 PF00076.22 PSC73542.1 - 2e-28 98.0 0.0 1.2e-10 41.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PSC73542.1 - 1.7e-09 37.7 0.0 8.1e-05 22.6 0.0 3.4 4 0 0 4 4 4 2 RNA binding motif RRM_5 PF13893.6 PSC73542.1 - 0.00026 20.6 0.0 0.81 9.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 PSC73543.1 - 2e-28 98.0 0.0 1.2e-10 41.0 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PSC73543.1 - 1.6e-09 37.7 0.0 8e-05 22.6 0.0 3.4 4 0 0 4 4 4 2 RNA binding motif RRM_5 PF13893.6 PSC73543.1 - 0.00026 20.6 0.0 0.81 9.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Glyco_hydro_63 PF03200.16 PSC73544.1 - 8e-183 608.7 0.0 1e-182 608.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 PSC73544.1 - 9.7e-39 133.8 0.5 1.4e-33 116.9 0.4 3.1 3 0 0 3 3 3 2 Glycosyl hydrolase family 63 N-terminal domain zf-HC5HC2H PF13771.6 PSC73544.1 - 1.1e-10 41.6 1.1 2.3e-10 40.6 1.1 1.6 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 PSC73544.1 - 1.5e-05 25.1 4.2 2.6e-05 24.3 4.2 1.4 1 0 0 1 1 1 1 PHD-zinc-finger like domain GDE_C PF06202.14 PSC73544.1 - 0.0013 17.7 0.2 0.0022 17.0 0.2 1.2 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase B3 PF02362.21 PSC73544.1 - 0.094 12.6 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 B3 DNA binding domain DUF4505 PF14956.6 PSC73544.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4505) PBP1_TM PF14812.6 PSC73544.1 - 3.8 7.9 5.3 12 6.3 5.3 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF512 PF04459.12 PSC73545.1 - 0.11 11.7 0.2 0.42 9.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF512) Pkinase PF00069.25 PSC73546.1 - 2.9e-41 141.6 0.0 1.1e-40 139.7 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73546.1 - 3.9e-37 128.0 0.0 1.6e-36 125.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase PAN_4 PF14295.6 PSC73546.1 - 1.7e-07 31.0 23.6 0.002 18.0 3.0 4.3 5 0 0 5 5 5 3 PAN domain PAN_1 PF00024.26 PSC73546.1 - 4.3e-06 26.6 12.1 0.0001 22.2 1.2 3.1 3 0 0 3 3 3 2 PAN domain RCR PF12273.8 PSC73546.1 - 0.049 14.3 0.1 0.13 13.0 0.1 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Kinase-like PF14531.6 PSC73546.1 - 0.085 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 PSC73546.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase GTP_EFTU PF00009.27 PSC73547.1 - 2.2e-31 108.9 0.4 1.5e-30 106.2 0.0 2.7 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 PSC73547.1 - 2.2e-21 75.9 0.0 5.1e-21 74.8 0.0 1.6 1 0 0 1 1 1 1 Translation-initiation factor 2 tRNA_bind PF01588.20 PSC73547.1 - 4.3e-19 68.4 0.5 1.3e-18 66.9 0.5 1.9 1 0 0 1 1 1 1 Putative tRNA binding domain GTP_EFTU_D2 PF03144.25 PSC73547.1 - 4e-14 52.8 2.3 3.2e-09 37.0 0.3 4.1 3 0 0 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 PSC73547.1 - 2e-12 46.8 0.0 5.6e-12 45.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 PSC73547.1 - 7.4e-06 26.0 0.1 8.7e-05 22.6 0.0 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase Roc PF08477.13 PSC73547.1 - 0.01 16.0 0.0 0.021 15.0 0.0 1.5 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Dala_Dala_lig_N PF01820.21 PSC73547.1 - 0.14 12.6 3.5 15 6.1 0.1 4.0 4 0 0 4 4 4 0 D-ala D-ala ligase N-terminus bHLH-MYC_N PF14215.6 PSC73547.1 - 1.1 9.5 0.0 1.1 9.5 0.0 3.8 3 2 0 3 3 3 0 bHLH-MYC and R2R3-MYB transcription factors N-terminal TFIIA PF03153.13 PSC73548.1 - 0.0024 18.0 22.7 0.0026 17.8 22.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Tim54 PF11711.8 PSC73548.1 - 0.027 13.2 7.1 0.036 12.8 7.1 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PAT1 PF09770.9 PSC73548.1 - 0.19 10.0 20.6 0.23 9.7 20.6 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Connexin PF00029.19 PSC73548.1 - 0.22 11.3 0.3 0.34 10.6 0.3 1.3 1 0 0 1 1 1 0 Connexin Neur_chan_memb PF02932.16 PSC73548.1 - 0.29 11.2 3.2 0.34 10.9 3.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Spt20 PF12090.8 PSC73548.1 - 0.33 10.5 29.3 0.48 10.0 29.3 1.2 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 PSC73548.1 - 0.8 8.4 9.8 0.96 8.1 9.8 1.1 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 PSC73548.1 - 0.86 9.0 6.8 1.1 8.7 6.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Lin-8 PF03353.15 PSC73548.1 - 1 8.8 10.0 1.2 8.6 10.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CPSF100_C PF13299.6 PSC73548.1 - 4.5 7.4 7.6 7 6.8 7.6 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SpoIIP PF07454.11 PSC73548.1 - 4.6 6.6 8.6 5.9 6.3 8.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) GREB1 PF15782.5 PSC73548.1 - 7 3.6 8.1 7.8 3.5 8.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SRP-alpha_N PF04086.13 PSC73548.1 - 7.4 6.4 11.3 10 5.9 11.3 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF760 PF05542.11 PSC73550.1 - 5.7e-37 125.9 2.6 1.5e-18 66.9 0.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF760) Mu-like_Pro PF10123.9 PSC73550.1 - 0.068 12.7 0.1 0.14 11.7 0.1 1.6 1 0 0 1 1 1 0 Mu-like prophage I protein AAA_34 PF13872.6 PSC73551.1 - 1.9e-116 388.2 0.0 2.8e-116 387.7 0.0 1.3 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 PSC73551.1 - 9.3e-109 363.3 0.0 1.5e-108 362.6 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain on Strawberry notch homologue UBA PF00627.31 PSC73551.1 - 9.4e-09 35.0 0.1 2.3e-08 33.8 0.1 1.7 1 0 0 1 1 1 1 UBA/TS-N domain RRM_1 PF00076.22 PSC73552.1 - 1.3e-17 63.4 0.0 4.4e-09 36.0 0.0 2.8 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GYF_2 PF14237.6 PSC73552.1 - 2.1e-09 37.1 0.8 4.2e-09 36.1 0.8 1.6 1 0 0 1 1 1 1 GYF domain 2 GYF PF02213.16 PSC73552.1 - 2.5e-06 27.0 0.5 5.1e-06 26.1 0.5 1.6 1 0 0 1 1 1 1 GYF domain RRM_7 PF16367.5 PSC73552.1 - 5.8e-05 23.1 0.0 0.00011 22.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif THDPS_N_2 PF14805.6 PSC73552.1 - 0.23 11.7 1.7 2.4 8.4 0.4 2.7 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal Thymidylate_kin PF02223.17 PSC73553.1 - 9.9e-44 149.2 0.0 1.2e-43 149.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase GP3 PF03076.14 PSC73553.1 - 0.15 12.1 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Equine arteritis virus GP3 Bestrophin PF01062.21 PSC73554.1 - 2.2e-27 96.2 4.2 3.3e-27 95.6 4.2 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel MSA-2c PF12238.8 PSC73555.1 - 2.4 8.1 7.8 3.6 7.5 7.8 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c RSN1_7TM PF02714.15 PSC73556.1 - 2.3e-43 148.5 21.6 2.1e-38 132.2 7.4 2.2 1 1 1 2 2 2 2 Calcium-dependent channel, 7TM region, putative phosphate NatB_MDM20 PF09797.9 PSC73556.1 - 1.3e-31 109.9 0.0 2e-31 109.3 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit PHM7_cyt PF14703.6 PSC73556.1 - 6.5e-15 55.8 0.3 2e-14 54.2 0.0 2.0 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_TM PF13967.6 PSC73556.1 - 6.8e-07 29.2 1.2 0.00058 19.6 0.0 3.3 3 0 0 3 3 3 2 Late exocytosis, associated with Golgi transport TPR_19 PF14559.6 PSC73556.1 - 0.0017 18.9 0.5 0.0017 18.9 0.5 8.2 9 0 0 9 9 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 PSC73556.1 - 0.0041 17.8 5.0 0.0041 17.8 5.0 14.9 14 3 2 16 16 10 2 Tetratricopeptide repeat FeS_assembly_P PF01883.19 PSC73556.1 - 0.0063 16.7 0.0 0.0063 16.7 0.0 2.9 2 0 0 2 2 1 1 Iron-sulfur cluster assembly protein TPR_1 PF00515.28 PSC73556.1 - 0.041 13.7 0.6 0.21 11.5 0.6 2.4 1 0 0 1 1 1 0 Tetratricopeptide repeat MliC PF09864.9 PSC73556.1 - 0.046 13.7 0.3 0.17 11.9 0.3 2.0 1 0 0 1 1 1 0 Membrane-bound lysozyme-inhibitor of c-type lysozyme TPR_2 PF07719.17 PSC73556.1 - 0.22 11.8 15.0 0.027 14.6 1.9 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 PSC73556.1 - 1.2 9.3 3.8 2.8 8.2 0.3 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Fea1 PF07692.11 PSC73557.1 - 2.1e-24 86.3 17.5 3.2e-24 85.7 17.5 1.3 1 0 0 1 1 1 1 Low iron-inducible periplasmic protein CoA_binding PF02629.19 PSC73557.1 - 0.95 10.2 5.5 0.26 12.0 1.0 2.5 2 0 0 2 2 2 0 CoA binding domain Reticulon PF02453.17 PSC73558.1 - 0.0026 17.7 0.0 0.0026 17.7 0.0 2.7 4 0 0 4 4 4 1 Reticulon Maff2 PF12750.7 PSC73558.1 - 0.034 14.0 0.7 0.034 14.0 0.7 2.4 3 1 0 3 3 3 0 Maff2 family DUF1295 PF06966.12 PSC73559.1 - 5.5e-50 170.1 6.3 7.1e-50 169.7 6.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ERG4_ERG24 PF01222.17 PSC73559.1 - 0.047 12.5 3.2 0.099 11.4 0.7 2.0 2 0 0 2 2 2 0 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 PSC73559.1 - 0.18 12.2 2.5 1 9.8 0.0 2.7 2 1 0 2 2 2 0 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Ndc1_Nup PF09531.10 PSC73560.1 - 3.2 6.3 3.5 3.8 6.1 3.5 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MoCF_biosynth PF00994.24 PSC73562.1 - 1.9e-29 102.2 0.0 2.5e-29 101.8 0.0 1.1 1 0 0 1 1 1 1 Probable molybdopterin binding domain Prismane PF03063.20 PSC73563.1 - 3.4e-126 421.9 0.0 5.3e-125 418.0 0.0 2.0 1 1 0 1 1 1 1 Prismane/CO dehydrogenase family Smg4_UPF3 PF03467.15 PSC73563.1 - 2.3e-41 141.7 3.0 2.5e-41 141.6 0.0 2.3 2 0 0 2 2 2 1 Smg-4/UPF3 family RNF220 PF15926.5 PSC73563.1 - 0.0069 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 TFIIA PF03153.13 PSC73563.1 - 8.4 6.3 22.1 2 8.3 13.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Prismane PF03063.20 PSC73564.1 - 3.4e-126 421.9 0.0 5.3e-125 418.0 0.0 2.0 1 1 0 1 1 1 1 Prismane/CO dehydrogenase family Smg4_UPF3 PF03467.15 PSC73564.1 - 2.3e-41 141.7 3.0 2.5e-41 141.6 0.0 2.3 2 0 0 2 2 2 1 Smg-4/UPF3 family RNF220 PF15926.5 PSC73564.1 - 0.0069 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 TFIIA PF03153.13 PSC73564.1 - 8.4 6.3 22.1 2 8.3 13.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Prismane PF03063.20 PSC73565.1 - 3.4e-126 421.9 0.0 5.3e-125 418.0 0.0 2.0 1 1 0 1 1 1 1 Prismane/CO dehydrogenase family Smg4_UPF3 PF03467.15 PSC73565.1 - 2.3e-41 141.7 3.0 2.5e-41 141.6 0.0 2.3 2 0 0 2 2 2 1 Smg-4/UPF3 family RNF220 PF15926.5 PSC73565.1 - 0.0069 16.0 0.0 0.016 14.9 0.0 1.5 1 0 0 1 1 1 1 E3 ubiquitin-protein ligase RNF220 TFIIA PF03153.13 PSC73565.1 - 8.4 6.3 22.1 2 8.3 13.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FGGY_N PF00370.21 PSC73566.1 - 2.5e-71 240.1 0.0 3.3e-71 239.7 0.0 1.2 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 PSC73566.1 - 2.8e-61 206.7 5.7 3.9e-61 206.2 4.2 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain 2_5_RNA_ligase2 PF13563.6 PSC73568.1 - 0.0029 17.5 0.1 0.0059 16.5 0.1 1.6 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily DUF2623 PF11115.8 PSC73569.1 - 0.14 12.2 0.0 0.54 10.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2623) HIT PF01230.23 PSC73570.1 - 3.5e-25 88.6 0.0 5.1e-25 88.1 0.0 1.2 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 PSC73570.1 - 0.00034 21.0 0.0 0.00052 20.5 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding CDC73_C PF05179.14 PSC73571.1 - 1.3e-43 148.4 0.0 2.2e-43 147.7 0.0 1.3 1 0 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family, C-terminal CDC73_N PF16050.5 PSC73571.1 - 8e-25 87.8 1.0 1.5e-20 73.7 0.0 2.5 2 1 1 3 3 3 2 Paf1 complex subunit CDC73 N-terminal Pyr_redox_2 PF07992.14 PSC73572.1 - 8.2e-62 209.1 1.4 1.3e-61 208.4 1.4 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DUF789 PF05623.12 PSC73572.1 - 1e-56 192.8 0.0 2.9e-50 171.6 0.0 2.4 2 1 0 2 2 2 2 Protein of unknown function (DUF789) Pyr_redox_dim PF02852.22 PSC73572.1 - 2e-32 111.7 0.1 4.9e-32 110.5 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 PSC73572.1 - 5.8e-21 74.9 2.4 1.4e-20 73.6 0.0 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PSC73572.1 - 4.8e-10 39.2 0.3 1.1e-09 38.1 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PSC73572.1 - 4.9e-05 22.6 0.0 0.0023 17.1 0.0 2.3 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 PSC73572.1 - 0.012 14.9 0.7 0.027 13.7 0.2 1.7 2 0 0 2 2 2 0 Thi4 family 2-Hacid_dh_C PF02826.19 PSC73572.1 - 0.37 10.1 1.8 0.91 8.9 0.0 2.3 3 0 0 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.25 PSC73573.1 - 8.8e-43 146.6 0.0 1.3e-42 146.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Histone_H2A_C PF16211.5 PSC73573.1 - 9.2e-19 66.9 2.4 1.9e-18 65.9 2.4 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 PSC73573.1 - 3.1e-14 53.4 0.0 5.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Pkinase_Tyr PF07714.17 PSC73573.1 - 1.4e-11 44.2 0.0 2.7e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase CBFD_NFYB_HMF PF00808.23 PSC73573.1 - 0.00022 21.4 0.0 0.00041 20.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone APH PF01636.23 PSC73573.1 - 0.002 18.1 9.4 0.053 13.4 0.0 3.6 4 2 1 5 5 5 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PSC73573.1 - 0.041 12.7 0.0 0.078 11.7 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase ACT_4 PF13291.6 PSC73573.1 - 0.22 12.1 0.1 13 6.4 0.0 2.3 2 0 0 2 2 2 0 ACT domain Pkinase PF00069.25 PSC73574.1 - 8.9e-43 146.5 0.0 1.2e-42 146.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Histone_H2A_C PF16211.5 PSC73574.1 - 9.1e-19 66.9 2.4 1.8e-18 65.9 2.4 1.6 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 PSC73574.1 - 3.1e-14 53.5 0.0 5.2e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Pkinase_Tyr PF07714.17 PSC73574.1 - 1.5e-11 44.1 0.0 2.7e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase CBFD_NFYB_HMF PF00808.23 PSC73574.1 - 0.00022 21.5 0.0 0.0004 20.6 0.0 1.5 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone APH PF01636.23 PSC73574.1 - 0.0017 18.3 9.3 0.051 13.5 0.0 3.6 4 2 1 5 5 5 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PSC73574.1 - 0.04 12.7 0.0 0.077 11.8 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase PsiB PF06290.11 PSC73574.1 - 0.073 12.5 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 Plasmid SOS inhibition protein (PsiB) ACT_4 PF13291.6 PSC73574.1 - 0.22 12.2 0.1 13 6.4 0.0 2.3 2 0 0 2 2 2 0 ACT domain Tmemb_14 PF03647.13 PSC73575.1 - 3e-18 66.3 11.7 4.7e-18 65.7 11.7 1.2 1 0 0 1 1 1 1 Transmembrane proteins 14C Col_cuticle_N PF01484.17 PSC73575.1 - 4.4 7.4 4.1 4.6 7.4 0.3 2.2 2 0 0 2 2 2 0 Nematode cuticle collagen N-terminal domain Cupin_8 PF13621.6 PSC73576.1 - 2e-63 214.5 0.0 5.1e-63 213.2 0.0 1.7 1 0 0 1 1 1 1 Cupin-like domain cobW PF02492.19 PSC73576.1 - 5.8e-58 195.4 2.8 9.6e-58 194.7 2.8 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 PSC73576.1 - 2.2e-20 72.4 0.0 5.8e-20 71.0 0.0 1.8 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain HLH PF00010.26 PSC73576.1 - 2.4e-10 40.2 0.0 8.3e-10 38.5 0.0 2.0 2 0 0 2 2 2 1 Helix-loop-helix DNA-binding domain ACT PF01842.25 PSC73576.1 - 2.6e-06 27.1 0.1 1.1e-05 25.1 0.1 2.1 1 0 0 1 1 1 1 ACT domain RsgA_GTPase PF03193.16 PSC73576.1 - 0.0022 17.9 0.8 1.5 8.7 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase ACT_4 PF13291.6 PSC73576.1 - 0.051 14.2 0.0 0.2 12.2 0.0 2.0 2 0 0 2 2 2 0 ACT domain MMR_HSR1 PF01926.23 PSC73576.1 - 0.21 11.7 0.5 0.9 9.6 0.5 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase MeaB PF03308.16 PSC73576.1 - 0.27 10.2 1.6 0.75 8.7 0.1 2.3 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB LPMO_10 PF03067.15 PSC73577.1 - 4.2e-11 43.9 0.1 5.4e-11 43.5 0.1 1.2 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading CBM_14 PF01607.24 PSC73577.1 - 1.6e-08 34.6 3.8 1.6e-08 34.6 3.8 2.0 2 1 0 2 2 2 1 Chitin binding Peritrophin-A domain YGGT PF02325.17 PSC73578.1 - 1.2e-14 54.5 3.2 2.3e-14 53.5 3.2 1.5 1 0 0 1 1 1 1 YGGT family bZIP_1 PF00170.21 PSC73578.1 - 4.2e-05 23.5 14.4 0.00011 22.3 14.4 1.7 1 0 0 1 1 1 1 bZIP transcription factor NRBF2 PF08961.10 PSC73578.1 - 0.074 12.6 2.8 0.15 11.7 2.8 1.5 1 0 0 1 1 1 0 Nuclear receptor-binding factor 2, autophagy regulator NDT80_PhoG PF05224.12 PSC73578.1 - 0.3 11.3 3.5 0.51 10.5 3.5 1.2 1 0 0 1 1 1 0 NDT80 / PhoG like DNA-binding family DUF1640 PF07798.11 PSC73578.1 - 1.2 9.1 10.9 11 6.0 10.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) DUF4719 PF15843.5 PSC73579.1 - 0.59 10.2 3.1 0.78 9.8 2.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4719) TFIIA PF03153.13 PSC73579.1 - 1.7 8.6 9.2 2.1 8.3 9.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit K_trans PF02705.16 PSC73584.1 - 2.3e-184 613.9 18.7 2.8e-184 613.6 18.7 1.1 1 0 0 1 1 1 1 K+ potassium transporter RsfS PF02410.15 PSC73585.1 - 4.1e-20 72.1 0.0 6.5e-20 71.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation Dehydrin PF00257.19 PSC73585.1 - 0.033 14.7 1.3 0.059 13.9 1.3 1.4 1 0 0 1 1 1 0 Dehydrin PreAtp-grasp PF18604.1 PSC73585.1 - 0.094 12.4 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Pre ATP-grasp domain DinB_2 PF12867.7 PSC73585.1 - 0.11 13.0 0.4 0.24 11.9 0.4 1.8 1 1 0 1 1 1 0 DinB superfamily PGA2 PF07543.12 PSC73585.1 - 0.41 10.6 2.5 6.1 6.8 2.0 2.2 2 0 0 2 2 2 0 Protein trafficking PGA2 SBP PF03110.14 PSC73586.1 - 1.3e-25 89.5 5.9 2.2e-25 88.8 5.9 1.3 1 0 0 1 1 1 1 SBP domain TFIIA PF03153.13 PSC73586.1 - 5.4 6.9 8.2 11 5.9 8.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SBP PF03110.14 PSC73587.1 - 1.3e-25 89.5 5.9 2.2e-25 88.8 5.9 1.3 1 0 0 1 1 1 1 SBP domain TFIIA PF03153.13 PSC73587.1 - 5.4 6.9 8.2 11 5.9 8.2 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_hydro_31 PF01055.26 PSC73588.1 - 6.4e-121 404.6 0.1 9.2e-121 404.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 IF3_N PF05198.16 PSC73588.1 - 2.1e-18 66.4 0.1 6.6e-18 64.8 0.1 1.9 1 0 0 1 1 1 1 Translation initiation factor IF-3, N-terminal domain NtCtMGAM_N PF16863.5 PSC73588.1 - 6.2e-13 49.0 0.0 1.1e-12 48.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase IF3_C PF00707.22 PSC73588.1 - 6.7e-11 42.0 0.0 1.2e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain Gal_mutarotas_2 PF13802.6 PSC73588.1 - 1.5e-09 38.0 0.6 3.2e-09 37.0 0.6 1.6 1 0 0 1 1 1 1 Galactose mutarotase-like CHCH PF06747.13 PSC73588.1 - 0.00067 19.7 6.2 0.0012 18.9 6.2 1.4 1 0 0 1 1 1 1 CHCH domain NDUF_B7 PF05676.13 PSC73588.1 - 0.18 11.6 4.5 0.38 10.5 4.5 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Trefoil PF00088.18 PSC73588.1 - 0.22 11.4 2.2 0.31 11.0 0.2 2.3 2 0 0 2 2 2 0 Trefoil (P-type) domain COX6B PF02297.17 PSC73588.1 - 0.83 9.9 8.3 1.7 8.9 8.3 1.5 1 0 0 1 1 1 0 Cytochrome oxidase c subunit VIb Methyltransf_4 PF02390.17 PSC73589.1 - 9.1e-49 165.2 0.1 3.5e-48 163.3 0.0 2.1 2 0 0 2 2 2 1 Putative methyltransferase WD40 PF00400.32 PSC73589.1 - 9e-12 45.3 2.5 0.026 15.4 0.0 6.5 7 0 0 7 7 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC73589.1 - 6.3e-08 32.8 0.1 1.7 9.0 0.0 6.4 5 2 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_25 PF13649.6 PSC73589.1 - 2.9e-05 24.7 0.0 0.00022 21.8 0.0 2.7 1 0 0 1 1 1 1 Methyltransferase domain FAM76 PF16046.5 PSC73589.1 - 0.0016 17.9 5.7 0.0016 17.9 5.7 4.1 2 2 1 3 3 2 1 FAM76 protein Methyltransf_11 PF08241.12 PSC73589.1 - 0.0016 19.1 0.0 0.01 16.5 0.0 2.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PSC73589.1 - 0.0056 16.2 0.0 0.02 14.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 PSC73589.1 - 0.11 11.6 0.0 0.19 10.8 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 PSC73589.1 - 0.12 12.4 0.0 0.12 12.4 0.0 3.6 3 2 0 3 3 2 0 Methyltransferase domain MPS2 PF17060.5 PSC73589.1 - 0.17 11.2 7.5 0.029 13.7 0.4 2.8 2 1 0 2 2 2 0 Monopolar spindle protein 2 CMAS PF02353.20 PSC73589.1 - 0.18 11.1 1.8 0.19 11.0 0.0 1.8 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase Methyltransf_31 PF13847.6 PSC73589.1 - 0.23 11.2 0.0 0.23 11.2 0.0 2.3 2 0 0 2 2 1 0 Methyltransferase domain SAGA-Tad1 PF12767.7 PSC73589.1 - 0.57 9.9 8.8 1.9 8.2 8.8 1.9 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Methyltransf_12 PF08242.12 PSC73589.1 - 0.7 10.7 0.0 0.7 10.7 0.0 2.7 2 0 0 2 2 1 0 Methyltransferase domain Rep_fac-A_C PF08646.10 PSC73590.1 - 1.6e-42 144.7 0.0 2.3e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 PSC73590.1 - 3.7e-26 90.9 0.1 1.6e-24 85.7 0.0 2.4 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 PSC73590.1 - 1.5e-25 89.1 0.2 2.5e-25 88.4 0.2 1.4 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 PSC73590.1 - 1.6e-12 47.2 0.5 3.9e-09 36.4 0.1 3.4 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.14 PSC73590.1 - 0.00042 20.5 0.0 0.0026 18.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF223 DUF5521 PF17659.1 PSC73590.1 - 0.1 10.5 0.0 2 6.2 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5521) BRCA-2_OB1 PF09103.10 PSC73590.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Rep_fac-A_C PF08646.10 PSC73591.1 - 1.6e-42 144.7 0.0 2.3e-42 144.2 0.0 1.3 1 0 0 1 1 1 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 PSC73591.1 - 3.7e-26 90.9 0.1 1.6e-24 85.7 0.0 2.4 2 0 0 2 2 2 1 Replication protein A OB domain Rep-A_N PF04057.12 PSC73591.1 - 1.5e-25 89.1 0.2 2.5e-25 88.4 0.2 1.4 1 0 0 1 1 1 1 Replication factor-A protein 1, N-terminal domain tRNA_anti-codon PF01336.25 PSC73591.1 - 1.6e-12 47.2 0.5 3.9e-09 36.4 0.1 3.4 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain DUF223 PF02721.14 PSC73591.1 - 0.00042 20.5 0.0 0.0026 18.0 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function DUF223 DUF5521 PF17659.1 PSC73591.1 - 0.1 10.5 0.0 2 6.2 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5521) BRCA-2_OB1 PF09103.10 PSC73591.1 - 0.11 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 Ank_3 PF13606.6 PSC73592.1 - 0.076 13.6 0.2 20 6.2 0.1 3.2 3 0 0 3 3 3 0 Ankyrin repeat ERGIC_N PF13850.6 PSC73593.1 - 2.7e-26 91.7 0.0 5.8e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) COPIIcoated_ERV PF07970.12 PSC73593.1 - 9.6e-25 87.7 0.0 1.8e-24 86.8 0.0 1.4 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter Thioredoxin PF00085.20 PSC73593.1 - 4.3e-19 68.4 0.0 9e-19 67.4 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 PSC73593.1 - 6.8e-05 22.4 0.0 0.00081 18.8 0.0 2.2 2 0 0 2 2 2 1 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 PSC73593.1 - 0.0052 17.2 0.0 0.0099 16.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Pkinase PF00069.25 PSC73594.1 - 2.2e-43 148.5 0.0 3.8e-43 147.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73594.1 - 1.9e-15 56.9 0.0 3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase LMWPc PF01451.21 PSC73594.1 - 4.7e-06 27.1 0.0 1e-05 25.9 0.0 1.6 1 0 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase Macoilin PF09726.9 PSC73594.1 - 0.86 8.1 4.7 1.6 7.2 4.7 1.3 1 0 0 1 1 1 0 Macoilin family TFIIA PF03153.13 PSC73594.1 - 5.8 6.8 20.6 0.66 9.9 9.4 3.2 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Pepdidase_M14_N PF18027.1 PSC73595.1 - 4.2e-36 123.6 0.2 6.5e-36 123.0 0.2 1.3 1 0 0 1 1 1 1 Cytosolic carboxypeptidase N-terminal domain Peptidase_M14 PF00246.24 PSC73595.1 - 9.1e-18 65.1 0.0 2.5e-17 63.6 0.0 1.7 1 0 0 1 1 1 1 Zinc carboxypeptidase Rad60-SLD PF11976.8 PSC73595.1 - 0.00074 19.3 0.0 0.0015 18.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ATP_transf PF09830.9 PSC73596.1 - 8.7e-16 57.8 0.0 1.8e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase HIT PF01230.23 PSC73596.1 - 0.15 12.8 0.1 0.73 10.6 0.1 2.1 1 1 0 1 1 1 0 HIT domain DUF4931 PF16285.5 PSC73596.1 - 0.23 10.7 0.0 0.58 9.4 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4931) Tape_meas_lam_C PF09718.10 PSC73597.1 - 0.27 11.4 3.6 0.38 10.9 1.3 2.2 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ISG65-75 PF11727.8 PSC73597.1 - 7.1 5.8 13.0 0.35 10.0 5.5 2.1 2 1 0 2 2 2 0 Invariant surface glycoprotein Ank_2 PF12796.7 PSC73598.1 - 5.1e-34 116.7 2.9 2.6e-12 47.1 0.1 4.1 3 2 1 4 4 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC73598.1 - 7.8e-32 109.2 0.2 5.2e-08 33.3 0.0 6.5 3 3 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC73598.1 - 5.2e-31 106.3 6.7 1.6e-11 44.2 0.0 5.6 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC73598.1 - 1.3e-26 89.7 6.6 0.00065 20.0 0.0 7.9 8 0 0 8 8 8 6 Ankyrin repeat Ank PF00023.30 PSC73598.1 - 1.1e-22 79.4 15.2 6.4e-06 26.4 0.0 7.0 7 0 0 7 7 7 5 Ankyrin repeat TPR_1 PF00515.28 PSC73598.1 - 3.1e-13 48.9 0.5 0.00032 20.4 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 PSC73598.1 - 3.5e-11 42.3 6.6 0.0007 19.5 0.7 4.1 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 PSC73598.1 - 3.6e-06 27.5 8.9 0.0021 18.7 0.1 5.4 5 2 1 6 6 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 PSC73598.1 - 0.00034 20.2 2.9 1.4 8.7 0.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_17 PF13431.6 PSC73598.1 - 0.0046 17.3 0.1 0.042 14.2 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PSC73598.1 - 0.0062 16.7 1.4 0.013 15.8 0.6 2.0 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 PSC73598.1 - 0.082 13.4 0.0 0.082 13.4 0.0 4.7 3 2 0 4 4 4 0 Tetratricopeptide repeat Ser_hydrolase PF06821.13 PSC73598.1 - 0.097 12.5 1.0 0.96 9.3 0.1 2.5 2 0 0 2 2 2 0 Serine hydrolase TPR_7 PF13176.6 PSC73598.1 - 0.12 12.4 1.5 7.5 6.8 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_9 PF13371.6 PSC73598.1 - 8.3 6.7 10.0 0.29 11.3 2.0 2.8 3 0 0 3 3 2 0 Tetratricopeptide repeat Ribosomal_L36 PF00444.18 PSC73599.1 - 2e-21 75.9 9.0 2.4e-21 75.7 9.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L36 TMA7 PF09072.10 PSC73599.1 - 0.67 10.8 3.4 0.73 10.7 2.0 1.6 1 1 1 2 2 2 0 Translation machinery associated TMA7 NTPase_I-T PF01931.18 PSC73600.1 - 2.5e-39 134.7 0.0 6.2e-39 133.4 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function DUF84 NUDIX PF00293.28 PSC73601.1 - 6.1e-12 45.7 0.1 1.1e-11 44.9 0.1 1.4 1 0 0 1 1 1 1 NUDIX domain BCAS3 PF12490.8 PSC73601.1 - 3.3e-10 39.9 0.0 3.2e-09 36.7 0.0 2.3 1 1 0 1 1 1 1 Breast carcinoma amplified sequence 3 WD40 PF00400.32 PSC73601.1 - 7.3e-05 23.5 0.6 0.68 10.9 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat TauE PF01925.19 PSC73602.1 - 2.8e-37 128.6 39.1 1.2e-18 67.6 14.1 2.2 2 0 0 2 2 2 2 Sulfite exporter TauE/SafE AAA_12 PF13087.6 PSC73604.1 - 3e-35 121.7 0.0 3.8e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PSC73604.1 - 1.8e-06 27.9 0.2 3.2e-06 27.1 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PSC73604.1 - 0.0003 20.6 0.0 0.00076 19.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 PSC73604.1 - 0.003 17.3 0.1 2.4 7.8 0.0 2.2 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 PSC73604.1 - 0.0064 16.3 0.2 0.026 14.3 0.2 2.1 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain Kinesin PF00225.23 PSC73606.1 - 1.4e-93 313.5 0.0 3.2e-93 312.3 0.0 1.6 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PSC73606.1 - 1.7e-21 76.7 0.0 3.4e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Ribonuclease_3 PF00636.26 PSC73606.1 - 0.027 15.1 0.0 0.1 13.3 0.0 2.0 1 0 0 1 1 1 0 Ribonuclease III domain Gag_p12 PF01141.18 PSC73606.1 - 0.84 10.0 8.5 0.25 11.7 4.5 2.3 2 0 0 2 2 2 0 Gag polyprotein, inner coat protein p12 DAO PF01266.24 PSC73607.1 - 2.3e-39 136.0 7.8 4.4e-39 135.1 7.8 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase Abhydrolase_6 PF12697.7 PSC73607.1 - 1.1e-10 42.5 17.9 1.1e-10 42.5 17.9 2.9 2 2 1 3 3 3 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 PSC73607.1 - 0.00087 19.2 0.0 0.0028 17.5 0.0 1.8 2 0 0 2 2 2 1 Serine hydrolase Hydrolase_4 PF12146.8 PSC73607.1 - 0.0012 18.1 0.0 0.017 14.4 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 PSC73607.1 - 0.0045 17.1 0.0 0.0087 16.2 0.0 1.4 1 0 0 1 1 1 1 Thioesterase domain FAD_binding_2 PF00890.24 PSC73607.1 - 0.0053 15.9 0.7 0.0053 15.9 0.7 1.6 2 0 0 2 2 1 1 FAD binding domain Abhydrolase_1 PF00561.20 PSC73607.1 - 0.022 14.4 0.0 0.048 13.3 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Thi4 PF01946.17 PSC73607.1 - 0.07 12.4 0.5 0.14 11.4 0.5 1.4 1 0 0 1 1 1 0 Thi4 family Abhydrolase_5 PF12695.7 PSC73607.1 - 0.13 12.1 0.0 9.6 5.9 0.0 2.4 3 0 0 3 3 3 0 Alpha/beta hydrolase family Pyr_redox_2 PF07992.14 PSC73607.1 - 0.14 11.3 0.3 0.26 10.5 0.3 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase LIDHydrolase PF10230.9 PSC73607.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Ald_Xan_dh_C2 PF02738.18 PSC73608.1 - 4.1e-132 441.4 0.4 5.8e-132 440.9 0.4 1.2 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase Ald_Xan_dh_C PF01315.22 PSC73608.1 - 3.5e-25 88.5 0.0 8e-25 87.3 0.0 1.6 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain FAD_binding_5 PF00941.21 PSC73608.1 - 4.4e-20 72.1 0.0 1.7e-18 66.9 0.0 2.7 1 1 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Fer2_2 PF01799.20 PSC73608.1 - 2.5e-19 69.1 2.5 2.5e-19 69.1 2.5 2.4 2 1 1 3 3 3 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 PSC73608.1 - 1.5e-06 28.3 4.3 1.5e-06 28.3 4.3 2.6 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 PSC73608.1 - 0.00016 21.5 0.5 0.00057 19.8 0.5 2.0 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 PSC73608.1 - 0.032 14.0 1.3 0.1 12.4 1.3 1.8 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Aldo_ket_red PF00248.21 PSC73609.1 - 1.1e-67 228.3 0.0 1.6e-67 227.8 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2232 PF09991.9 PSC73610.1 - 1.8e-13 50.4 17.2 2.5e-12 46.6 17.2 2.0 1 1 0 1 1 1 1 Predicted membrane protein (DUF2232) Per1 PF04080.13 PSC73611.1 - 3.2e-71 240.1 1.8 8.2e-71 238.7 1.8 1.6 1 1 0 1 1 1 1 Per1-like family RMI2 PF16100.5 PSC73611.1 - 1.2e-08 34.8 0.0 2.3e-08 33.9 0.0 1.4 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 tRNA_anti-codon PF01336.25 PSC73611.1 - 0.0065 16.4 0.0 0.018 15.0 0.0 1.7 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain Coprogen_oxidas PF01218.18 PSC73612.1 - 3.4e-121 403.5 0.8 3.9e-121 403.3 0.8 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase ketoacyl-synt PF00109.26 PSC73613.1 - 3.3e-265 875.4 77.7 3e-49 167.9 4.9 7.6 6 0 0 6 6 6 6 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 PSC73613.1 - 4.1e-168 554.7 74.2 5.1e-37 127.5 10.9 6.9 6 0 0 6 6 6 6 KR domain Ketoacyl-synt_C PF02801.22 PSC73613.1 - 1.8e-153 502.1 48.7 3e-27 95.0 1.3 8.3 7 0 0 7 7 7 6 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 PSC73613.1 - 3.5e-145 472.6 16.7 5.7e-14 52.2 0.0 11.7 11 0 0 11 11 11 11 Phosphopantetheine attachment site PS-DH PF14765.6 PSC73613.1 - 3.2e-45 154.6 44.5 1.4e-14 54.0 9.2 9.4 6 3 2 8 8 8 7 Polyketide synthase dehydratase Nucleoporin2 PF04096.14 PSC73613.1 - 2.3e-19 70.0 0.0 3.4e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase KAsynt_C_assoc PF16197.5 PSC73613.1 - 5.4e-19 68.7 5.5 0.15 12.5 0.0 7.3 7 0 0 7 7 7 6 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 PSC73613.1 - 4.2e-05 23.0 35.9 0.16 11.3 0.8 7.1 7 0 0 7 7 7 6 Thiolase, N-terminal domain adh_short PF00106.25 PSC73613.1 - 0.0025 17.3 0.5 0.0025 17.3 0.5 6.4 8 0 0 8 8 8 4 short chain dehydrogenase DEK_C PF08766.11 PSC73613.1 - 0.097 12.6 0.0 2.6e+02 1.6 0.0 5.7 8 0 0 8 8 8 0 DEK C terminal domain dNK PF01712.19 PSC73614.1 - 6.1e-51 173.2 0.0 1e-50 172.5 0.0 1.3 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 PSC73614.1 - 0.00036 21.1 0.0 0.0098 16.4 0.0 2.7 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 PSC73614.1 - 0.001 19.6 0.0 0.0031 18.0 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_33 PF13671.6 PSC73614.1 - 0.0031 17.7 0.0 0.085 13.0 0.0 2.7 1 1 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 PSC73614.1 - 0.017 15.2 0.0 0.05 13.7 0.0 1.8 2 0 0 2 2 2 0 Dynamin family AAA_17 PF13207.6 PSC73614.1 - 0.063 13.7 0.2 0.23 11.9 0.1 2.1 2 0 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 PSC73614.1 - 0.067 12.9 0.0 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 Thymidylate kinase SR-25 PF10500.9 PSC73614.1 - 0.19 11.3 3.6 0.45 10.1 3.6 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Ank_2 PF12796.7 PSC73616.1 - 7e-25 87.4 0.8 9.8e-08 32.5 0.1 5.4 5 0 0 5 5 5 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC73616.1 - 1.4e-13 51.1 0.1 0.0054 17.3 0.1 5.7 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC73616.1 - 3.1e-13 48.6 13.9 0.29 11.8 0.1 9.3 10 0 0 10 10 10 4 Ankyrin repeat Ank_5 PF13857.6 PSC73616.1 - 1.1e-11 44.7 12.4 0.0013 19.0 0.5 7.0 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 PSC73616.1 - 2.6e-11 43.4 17.0 0.024 15.1 0.2 7.7 8 0 0 8 8 8 4 Ankyrin repeat Ank_2 PF12796.7 PSC73617.1 - 1.4e-25 89.7 1.4 9.7e-08 32.5 0.1 5.5 5 0 0 5 5 5 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PSC73617.1 - 3.8e-14 51.4 12.8 0.29 11.8 0.1 9.6 10 0 0 10 10 10 4 Ankyrin repeat Ank_4 PF13637.6 PSC73617.1 - 1.2e-13 51.3 0.1 0.0054 17.3 0.1 5.8 5 1 2 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC73617.1 - 7e-12 45.3 13.2 0.0013 19.0 0.5 7.3 6 2 2 8 8 8 4 Ankyrin repeats (many copies) Ank PF00023.30 PSC73617.1 - 2.5e-11 43.5 17.0 0.024 15.1 0.2 7.7 8 0 0 8 8 8 4 Ankyrin repeat Ank_2 PF12796.7 PSC73620.1 - 1.1e-09 38.8 0.0 3.5e-09 37.1 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 PSC73620.1 - 1.3e-08 34.9 0.4 0.0016 18.8 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 PSC73620.1 - 2e-06 28.0 0.2 0.00075 19.8 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC73620.1 - 5.9e-06 26.2 0.4 0.19 12.4 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 PSC73620.1 - 6.7e-06 26.6 0.0 0.0029 18.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeats (many copies) DAO PF01266.24 PSC73621.1 - 1.5e-61 208.9 9.4 2e-61 208.6 9.4 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PSC73621.1 - 0.00015 21.0 8.5 0.00029 20.0 8.5 1.5 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 PSC73621.1 - 0.00016 21.0 0.9 0.00031 20.1 0.2 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PSC73621.1 - 0.00038 20.6 1.5 0.00038 20.6 1.5 2.2 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain AlaDh_PNT_C PF01262.21 PSC73621.1 - 0.04 13.2 0.1 0.063 12.6 0.1 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Thi4 PF01946.17 PSC73621.1 - 0.045 13.0 0.8 0.11 11.8 0.8 1.5 1 0 0 1 1 1 0 Thi4 family ThiF PF00899.21 PSC73621.1 - 0.11 11.8 0.3 0.3 10.4 0.2 1.7 2 0 0 2 2 2 0 ThiF family Lycopene_cycl PF05834.12 PSC73621.1 - 0.11 11.5 5.0 0.55 9.2 2.1 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein Pyr_redox PF00070.27 PSC73621.1 - 0.12 12.9 2.4 0.23 12.0 2.4 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 PSC73621.1 - 0.19 11.6 1.6 0.31 10.9 1.6 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_oxidored PF12831.7 PSC73621.1 - 0.26 10.6 3.0 0.54 9.5 3.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 PSC73621.1 - 0.43 9.2 7.0 0.049 12.3 2.5 1.6 2 0 0 2 2 2 0 HI0933-like protein Pyr_redox_3 PF13738.6 PSC73621.1 - 0.65 9.2 1.8 0.9 8.7 1.8 1.1 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 PSC73621.1 - 0.8 8.9 7.7 0.039 13.2 2.1 1.6 2 0 0 2 2 2 0 FAD binding domain PEP-CTERM PF07589.11 PSC73621.1 - 2.6 8.3 6.7 89 3.4 0.3 4.3 3 0 0 3 3 3 0 PEP-CTERM motif Cupredoxin_1 PF13473.6 PSC73622.1 - 0.028 14.5 0.0 0.17 12.0 0.0 2.1 2 0 0 2 2 2 0 Cupredoxin-like domain DUF2524 PF10732.9 PSC73623.1 - 0.17 12.2 0.6 1.1 9.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2524) DinB_2 PF12867.7 PSC73623.1 - 0.48 10.9 5.9 0.38 11.3 0.9 2.8 1 1 0 2 2 2 0 DinB superfamily DUF5132 PF17195.4 PSC73623.1 - 6 7.1 9.1 2.5 8.3 5.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF5132) MT-A70 PF05063.14 PSC73624.1 - 7.2e-06 26.0 0.0 1.1e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 MT-A70 Spt20 PF12090.8 PSC73624.1 - 0.36 10.4 5.1 0.54 9.8 5.1 1.2 1 0 0 1 1 1 0 Spt20 family DUF2465 PF10239.9 PSC73625.1 - 8e-34 117.3 0.0 1.1e-33 116.9 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) JmjC PF02373.22 PSC73626.1 - 1.1e-34 119.3 0.1 2.3e-34 118.3 0.1 1.6 1 0 0 1 1 1 1 JmjC domain, hydroxylase SDA1 PF05285.12 PSC73626.1 - 0.06 12.8 8.7 0.1 12.0 8.7 1.3 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 PSC73626.1 - 0.23 9.7 9.1 0.34 9.2 9.1 1.1 1 0 0 1 1 1 0 CDC45-like protein TFIIF_alpha PF05793.12 PSC73626.1 - 0.27 9.8 14.2 0.39 9.2 14.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Mpp10 PF04006.12 PSC73626.1 - 1.9 6.9 13.2 2.6 6.4 13.2 1.1 1 0 0 1 1 1 0 Mpp10 protein DUF2052 PF09747.9 PSC73626.1 - 2.1 8.4 13.4 3.4 7.7 13.4 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Nop14 PF04147.12 PSC73626.1 - 3.7 5.6 11.4 5 5.2 11.4 1.1 1 0 0 1 1 1 0 Nop14-like family Nha1_C PF08619.10 PSC73626.1 - 4 6.5 26.6 6.2 5.9 26.6 1.2 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Apt1 PF10351.9 PSC73626.1 - 4.8 5.9 6.0 6.5 5.5 6.0 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain DNA_pol_phi PF04931.13 PSC73626.1 - 5.6 4.9 12.3 8 4.4 12.3 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF4477 PF14780.6 PSC73627.1 - 3.1e-05 23.7 0.1 4.4e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4477) rve PF00665.26 PSC73629.1 - 5.9e-19 68.4 0.0 1.3e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC73629.1 - 0.0011 18.6 0.0 0.003 17.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Vps35 PF03635.17 PSC73631.1 - 8.7e-235 781.6 0.0 1.2e-227 758.0 0.0 2.0 2 0 0 2 2 2 2 Vacuolar protein sorting-associated protein 35 Rhodanese PF00581.20 PSC73631.1 - 2.8e-08 34.2 0.0 5.7e-08 33.2 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_2 PF00891.18 PSC73632.1 - 3.2e-13 49.5 0.1 1.4e-10 40.9 0.0 3.1 1 1 1 2 2 2 2 O-methyltransferase domain Pyr_redox_2 PF07992.14 PSC73632.1 - 3.9e-10 39.4 0.0 9.1e-09 35.0 0.0 2.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase SET PF00856.28 PSC73632.1 - 9.5e-09 35.9 0.0 3.6e-08 34.0 0.0 2.1 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 PSC73632.1 - 5.5e-07 30.3 0.0 3.1e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding NAD_binding_8 PF13450.6 PSC73632.1 - 0.0053 17.0 0.0 0.018 15.3 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.6 PSC73632.1 - 0.071 13.1 0.0 0.23 11.4 0.0 2.0 1 1 0 1 1 1 0 FAD-NAD(P)-binding HEAT PF02985.22 PSC73633.1 - 8.2e-13 47.4 13.4 0.0062 16.7 0.7 7.4 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.6 PSC73633.1 - 7.1e-06 26.4 18.7 9.7e-06 26.0 1.5 6.2 6 1 0 6 6 6 1 HEAT-like repeat HEAT_2 PF13646.6 PSC73633.1 - 1.5e-05 25.3 5.0 0.0028 18.0 0.1 5.0 5 2 1 6 6 6 1 HEAT repeats Vac14_Fab1_bd PF12755.7 PSC73633.1 - 0.0001 22.8 0.0 0.27 11.9 0.0 4.0 4 1 1 5 5 5 1 Vacuolar 14 Fab1-binding region DNA_alkylation PF08713.11 PSC73633.1 - 0.00097 18.9 1.6 0.0082 15.9 0.2 2.9 3 1 0 3 3 3 1 DNA alkylation repair enzyme IFRD PF05004.13 PSC73633.1 - 0.0034 16.5 0.3 1.6 7.8 0.0 2.3 2 0 0 2 2 2 2 Interferon-related developmental regulator (IFRD) UME PF08064.13 PSC73633.1 - 0.012 15.5 0.0 0.087 12.8 0.0 2.4 2 0 0 2 2 2 0 UME (NUC010) domain TrwC PF08751.11 PSC73633.1 - 0.033 13.7 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 TrwC relaxase Ribosomal_S21 PF01165.20 PSC73634.1 - 1.2e-21 76.1 1.3 1.9e-21 75.5 1.3 1.3 1 0 0 1 1 1 1 Ribosomal protein S21 AAA_2 PF07724.14 PSC73636.1 - 5.6e-44 150.3 0.0 2.1e-36 125.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 PSC73636.1 - 6.9e-14 52.4 0.4 4.1e-06 27.3 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 PSC73636.1 - 1.5e-07 31.3 1.9 2.4e-06 27.5 0.1 2.6 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 PSC73636.1 - 5.6e-07 29.6 0.1 6.1e-05 23.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PSC73636.1 - 3.3e-05 24.3 0.1 0.004 17.6 0.0 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PSC73636.1 - 0.00013 22.2 0.0 0.0014 18.9 0.0 2.6 3 0 0 3 3 3 1 AAA domain MCM PF00493.23 PSC73636.1 - 0.00015 21.0 0.0 0.007 15.5 0.0 2.3 2 0 0 2 2 2 1 MCM P-loop domain Zeta_toxin PF06414.12 PSC73636.1 - 0.0003 20.1 0.0 0.00057 19.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin Mg_chelatase PF01078.21 PSC73636.1 - 0.00092 18.6 0.0 0.0027 17.1 0.0 1.7 2 0 0 2 2 1 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 PSC73636.1 - 0.0019 17.9 0.0 0.12 12.2 0.0 2.5 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 PSC73636.1 - 0.0051 17.0 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PSC73636.1 - 0.0084 16.7 0.0 0.023 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.25 PSC73636.1 - 0.012 15.3 0.1 0.03 14.0 0.0 1.7 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.26 PSC73636.1 - 0.012 15.3 0.0 0.18 11.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 PSC73636.1 - 0.012 15.9 0.0 0.043 14.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_14 PF13173.6 PSC73636.1 - 0.016 15.3 0.1 2.9 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain T2SSE PF00437.20 PSC73636.1 - 0.021 13.9 0.0 0.6 9.1 0.0 2.3 1 1 1 2 2 2 0 Type II/IV secretion system protein TniB PF05621.11 PSC73636.1 - 0.04 13.3 0.1 0.13 11.6 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein TIP49 PF06068.13 PSC73636.1 - 0.04 13.1 0.0 0.078 12.2 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain Rad17 PF03215.15 PSC73636.1 - 0.057 13.3 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain TMEM223 PF14640.6 PSC73636.1 - 0.068 13.3 0.0 0.13 12.4 0.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 223 DUF2120 PF09893.9 PSC73636.1 - 0.088 12.9 0.7 5.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) ABC_tran PF00005.27 PSC73636.1 - 0.11 13.1 0.0 0.28 11.7 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_7 PF12775.7 PSC73636.1 - 0.11 11.9 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 PSC73636.1 - 0.15 11.8 0.0 0.43 10.3 0.0 1.8 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Torsin PF06309.11 PSC73636.1 - 0.21 11.7 0.0 0.45 10.6 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_8 PF12780.7 PSC73636.1 - 0.23 10.8 0.0 0.43 9.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region D4 Adap_comp_sub PF00928.21 PSC73641.1 - 1.9e-79 266.8 0.0 2.3e-79 266.5 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 PSC73641.1 - 4.9e-06 26.5 0.0 8.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain muHD PF10291.9 PSC73641.1 - 0.00016 21.2 0.2 0.00027 20.5 0.2 1.3 1 0 0 1 1 1 1 Muniscin C-terminal mu homology domain DUF4903 PF16246.5 PSC73641.1 - 0.058 13.0 0.1 0.1 12.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4903) Arm PF00514.23 PSC73643.1 - 6.4e-95 308.7 13.5 3.2e-13 49.2 0.0 8.5 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 PSC73643.1 - 2e-24 85.7 1.3 1.7e-07 31.6 0.0 5.7 4 1 0 4 4 4 3 HEAT-like repeat Arm_3 PF16186.5 PSC73643.1 - 3.5e-22 77.7 1.3 7.9e-22 76.6 1.3 1.6 1 0 0 1 1 1 1 Atypical Arm repeat IBB PF01749.20 PSC73643.1 - 1.7e-21 76.4 2.1 7.2e-21 74.4 1.7 2.1 2 0 0 2 2 2 1 Importin beta binding domain HEAT_2 PF13646.6 PSC73643.1 - 5.7e-19 68.3 1.9 4.9e-06 26.8 0.0 5.5 3 2 2 5 5 5 4 HEAT repeats HEAT PF02985.22 PSC73643.1 - 8.5e-13 47.4 5.1 5.2e-05 23.2 0.0 7.4 8 0 0 8 8 8 1 HEAT repeat Arm_2 PF04826.13 PSC73643.1 - 1e-09 38.3 0.0 0.0083 15.6 0.1 4.1 1 1 2 4 4 4 4 Armadillo-like V-ATPase_H_C PF11698.8 PSC73643.1 - 1.8e-06 28.0 0.0 0.94 9.6 0.0 4.7 4 2 0 4 4 4 1 V-ATPase subunit H NopRA1 PF16201.5 PSC73643.1 - 2.3e-06 27.4 0.0 2.7 7.5 0.0 4.4 3 2 0 3 3 3 2 Nucleolar pre-ribosomal-associated protein 1 RICTOR_V PF14668.6 PSC73643.1 - 8.3e-05 22.8 0.2 1.2 9.5 0.0 4.8 4 2 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 PSC73643.1 - 0.00027 21.3 2.1 0.46 11.3 0.1 5.2 5 0 0 5 5 5 1 PBS lyase HEAT-like repeat Cnd1 PF12717.7 PSC73643.1 - 0.00067 19.7 0.0 2.7 8.0 0.0 3.6 1 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Atx10homo_assoc PF09759.9 PSC73643.1 - 0.005 16.8 0.0 5.2 7.2 0.1 2.8 2 0 0 2 2 2 2 Spinocerebellar ataxia type 10 protein domain Aconitase_B_N PF11791.8 PSC73643.1 - 0.077 13.1 0.4 0.65 10.1 0.0 2.7 3 0 0 3 3 3 0 Aconitate B N-terminal domain SEN1_N PF12726.7 PSC73643.1 - 0.13 10.5 0.1 9.9 4.2 0.0 2.9 3 0 0 3 3 3 0 SEN1 N terminal Mo25 PF08569.11 PSC73643.1 - 0.2 11.0 0.0 1.1 8.5 0.0 2.1 2 1 0 3 3 3 0 Mo25-like DUF1351 PF07083.11 PSC73644.1 - 0.1 12.4 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1351) DUF3053 PF11254.8 PSC73644.1 - 0.18 11.4 1.5 0.96 9.0 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3053) Baculo_PEP_C PF04513.12 PSC73644.1 - 0.22 11.5 0.3 0.62 10.1 0.1 1.7 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus GTP_cyclohydroI PF01227.22 PSC73645.1 - 5.4e-76 254.0 0.0 1.5e-35 122.3 0.0 3.3 3 0 0 3 3 3 3 GTP cyclohydrolase I DUF2057 PF09829.9 PSC73645.1 - 0.93 9.6 9.5 0.88 9.7 0.5 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) Roughex PF06020.11 PSC73645.1 - 3.1 6.8 5.7 5.3 6.0 5.7 1.3 1 0 0 1 1 1 0 Drosophila roughex protein RRM_1 PF00076.22 PSC73646.1 - 1.4e-13 50.4 0.0 2.4e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PSC73646.1 - 0.00088 19.2 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 PSC73646.1 - 0.054 13.6 0.0 0.093 12.9 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif zf-like PF04071.12 PSC73646.1 - 0.23 11.4 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 Cysteine-rich small domain Asparaginase_2 PF01112.18 PSC73647.1 - 6e-47 160.2 9.9 1.1e-46 159.3 9.9 1.4 1 1 0 1 1 1 1 Asparaginase SR-25 PF10500.9 PSC73647.1 - 0.41 10.2 3.8 0.58 9.7 3.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cadherin_tail PF15974.5 PSC73647.1 - 0.91 9.9 6.4 6.4 7.1 0.1 2.3 1 1 1 2 2 2 0 Cadherin C-terminal cytoplasmic tail, catenin-binding region MOFRL PF05161.13 PSC73647.1 - 9.2 6.5 10.0 1.4 9.1 0.1 3.3 4 0 0 4 4 4 0 MOFRL family URO-D PF01208.17 PSC73649.1 - 1.8e-109 366.1 0.2 2e-109 365.9 0.2 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Pyr_redox_2 PF07992.14 PSC73650.1 - 9.3e-29 100.6 0.2 2.1e-15 56.8 0.2 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PSC73650.1 - 6.4e-09 36.2 2.0 0.00083 19.9 0.1 2.7 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PSC73650.1 - 0.00023 21.2 0.8 0.57 10.2 0.1 3.7 3 0 0 3 3 3 2 FAD-NAD(P)-binding DAO PF01266.24 PSC73650.1 - 0.00037 20.2 2.2 0.0011 18.6 2.2 2.0 1 1 0 1 1 1 1 FAD dependent oxidoreductase Rubredoxin_C PF18267.1 PSC73650.1 - 0.0055 16.6 0.0 0.01 15.7 0.0 1.4 1 0 0 1 1 1 1 Rubredoxin NAD+ reductase C-terminal domain SUIM_assoc PF16619.5 PSC73650.1 - 0.012 15.7 1.3 0.012 15.7 1.3 2.8 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 Glyco_transf_29 PF00777.18 PSC73650.1 - 0.053 12.9 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) HI0933_like PF03486.14 PSC73650.1 - 0.062 12.0 0.2 0.17 10.5 0.2 1.7 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 PSC73650.1 - 0.7 8.9 5.2 0.083 11.9 0.6 1.8 2 0 0 2 2 2 0 Lycopene cyclase protein DUF4666 PF15697.5 PSC73650.1 - 0.73 10.5 4.5 1.4 9.6 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4666) Med15 PF09606.10 PSC73650.1 - 6.5 5.3 33.5 0.14 10.9 2.7 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal MSP PF01716.18 PSC73651.1 - 7.8e-43 146.4 0.5 1.5e-40 138.9 0.5 2.1 1 1 0 1 1 1 1 Manganese-stabilising protein / photosystem II polypeptide MSP PF01716.18 PSC73652.1 - 2e-43 148.3 0.9 4.4e-37 127.6 0.4 2.2 2 0 0 2 2 2 2 Manganese-stabilising protein / photosystem II polypeptide TFIIA PF03153.13 PSC73652.1 - 0.74 9.8 9.2 1 9.3 9.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SARAF PF06682.12 PSC73652.1 - 3 7.4 5.0 4.6 6.8 5.0 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis Pex14_N PF04695.13 PSC73652.1 - 3.3 8.4 13.8 7.4 7.2 1.1 2.5 2 1 1 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region SET PF00856.28 PSC73654.1 - 2e-10 41.3 0.0 2e-10 41.3 0.0 7.1 2 2 0 2 2 2 1 SET domain Pre-SET PF05033.16 PSC73654.1 - 0.00012 22.7 3.1 0.00012 22.7 3.1 2.0 2 0 0 2 2 2 1 Pre-SET motif mTERF PF02536.14 PSC73655.1 - 2.2e-23 82.7 0.0 3.2e-22 78.9 0.0 2.1 1 1 0 1 1 1 1 mTERF Ribosomal_L28e PF01778.17 PSC73656.1 - 8.4e-23 81.3 2.0 1.1e-22 80.9 2.0 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family FAST_1 PF06743.15 PSC73657.1 - 1.9e-13 50.1 1.6 3.1 7.8 0.0 9.4 11 0 0 11 11 11 5 FAST kinase-like protein, subdomain 1 DUF3449 PF11931.8 PSC73657.1 - 0.079 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) LIM_bind PF01803.16 PSC73657.1 - 5.3 6.5 4.9 13 5.3 4.9 1.5 1 0 0 1 1 1 0 LIM-domain binding protein Pex14_N PF04695.13 PSC73657.1 - 8.1 7.1 15.8 9.3 6.9 4.4 3.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAST_1 PF06743.15 PSC73658.1 - 1.9e-13 50.1 1.6 3.1 7.8 0.0 9.4 11 0 0 11 11 11 5 FAST kinase-like protein, subdomain 1 DUF3449 PF11931.8 PSC73658.1 - 0.079 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) LIM_bind PF01803.16 PSC73658.1 - 5.3 6.5 4.9 13 5.3 4.9 1.5 1 0 0 1 1 1 0 LIM-domain binding protein Pex14_N PF04695.13 PSC73658.1 - 8.1 7.1 15.8 9.3 6.9 4.4 3.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAST_1 PF06743.15 PSC73659.1 - 3.8e-13 49.2 1.8 3.1 7.8 0.0 9.2 11 0 0 11 11 11 5 FAST kinase-like protein, subdomain 1 DUF3449 PF11931.8 PSC73659.1 - 0.079 12.8 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3449) LIM_bind PF01803.16 PSC73659.1 - 5.3 6.5 4.9 13 5.3 4.9 1.5 1 0 0 1 1 1 0 LIM-domain binding protein Pex14_N PF04695.13 PSC73659.1 - 8 7.1 15.8 9.2 6.9 4.4 3.6 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ferric_reduct PF01794.19 PSC73660.1 - 9e-12 45.2 13.9 3e-11 43.5 13.9 1.9 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 PSC73660.1 - 3.1e-08 33.7 0.0 5.5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 FAD-binding domain NAD_binding_6 PF08030.12 PSC73660.1 - 1.4e-06 28.5 0.0 7.1e-06 26.2 0.0 1.9 1 1 0 1 1 1 1 Ferric reductase NAD binding domain NAD_binding_1 PF00175.21 PSC73660.1 - 0.017 15.7 0.1 0.053 14.2 0.0 1.8 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain DSPn PF14671.6 PSC73661.1 - 5.9e-40 137.0 0.0 4e-38 131.0 0.0 2.3 2 0 0 2 2 2 1 Dual specificity protein phosphatase, N-terminal half DSPc PF00782.20 PSC73661.1 - 3.4e-13 49.6 0.0 5.8e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 PSC73661.1 - 3.7e-06 27.1 0.0 6.8e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 PSC73661.1 - 4.6e-05 23.1 0.0 7.4e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 PSC73661.1 - 0.03 14.3 0.0 0.057 13.4 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Unstab_antitox PF09720.10 PSC73662.1 - 0.0094 16.0 1.2 0.29 11.2 0.7 2.9 2 0 0 2 2 2 1 Putative addiction module component Unstab_antitox PF09720.10 PSC73663.1 - 0.0094 16.0 1.2 0.29 11.2 0.7 2.9 2 0 0 2 2 2 1 Putative addiction module component DNase_II PF03265.15 PSC73664.1 - 4.6e-18 65.6 0.0 6.9e-17 61.7 0.0 2.0 1 1 0 1 1 1 1 Deoxyribonuclease II ATP1G1_PLM_MAT8 PF02038.16 PSC73664.1 - 0.16 11.4 0.1 0.32 10.4 0.1 1.5 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family GIY-YIG PF01541.24 PSC73665.1 - 1.3e-11 44.6 0.0 2.2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 GIY-YIG catalytic domain Pkinase PF00069.25 PSC73666.1 - 2e-56 191.3 0.0 2.6e-56 190.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73666.1 - 1.5e-28 99.8 0.0 3.6e-28 98.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Mad3_BUB1_I PF08311.12 PSC73666.1 - 8.6e-08 32.2 0.0 1.8e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 APH PF01636.23 PSC73666.1 - 0.0016 18.4 0.1 0.004 17.1 0.1 5.0 3 2 1 4 4 4 2 Phosphotransferase enzyme family RIO1 PF01163.22 PSC73666.1 - 0.0021 17.7 0.0 0.0043 16.7 0.0 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 PSC73666.1 - 0.0076 15.6 0.1 0.015 14.7 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PSC73666.1 - 0.024 14.2 0.0 0.25 10.9 0.0 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 PSC73666.1 - 0.045 13.1 0.0 0.08 12.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 PSC73666.1 - 0.049 12.4 0.0 0.086 11.6 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase PGI PF00342.19 PSC73667.1 - 4.7e-198 658.7 0.0 1.2e-197 657.4 0.0 1.6 2 0 0 2 2 2 1 Phosphoglucose isomerase zf-MYND PF01753.18 PSC73667.1 - 0.0028 17.7 3.8 0.0065 16.5 3.8 1.6 1 0 0 1 1 1 1 MYND finger Enkurin PF13864.6 PSC73668.1 - 2.3e-24 85.7 6.3 4.2e-24 84.8 6.3 1.4 1 0 0 1 1 1 1 Calmodulin-binding DUF3287 PF11690.8 PSC73668.1 - 0.33 10.7 2.0 15 5.3 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) Ribosomal_L13 PF00572.18 PSC73669.1 - 1.6e-10 41.3 0.0 2e-08 34.5 0.0 2.4 1 1 0 1 1 1 1 Ribosomal protein L13 Aminotran_3 PF00202.21 PSC73670.1 - 1.3e-67 228.3 0.0 1.6e-67 227.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Fe_hyd_lg_C PF02906.14 PSC73671.1 - 2e-86 289.6 0.5 7.6e-66 222.2 0.1 2.5 2 0 0 2 2 2 2 Iron only hydrogenase large subunit, C-terminal domain CLTH PF10607.9 PSC73671.1 - 1.6e-23 83.2 0.0 3.3e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Fe_hyd_SSU PF02256.17 PSC73671.1 - 2.1e-22 78.9 0.1 3.9e-22 78.1 0.1 1.5 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer2_4 PF13510.6 PSC73671.1 - 1.9e-17 63.0 0.2 7.1e-17 61.2 0.2 2.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 PSC73671.1 - 5.9e-11 41.7 0.1 5.9e-11 41.7 0.1 2.6 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer4 PF00037.27 PSC73671.1 - 1.3e-10 40.6 18.6 3.4e-07 29.8 3.0 3.7 3 0 0 3 3 3 2 4Fe-4S binding domain PAP_assoc PF03828.19 PSC73671.1 - 1.3e-09 38.1 0.0 2.9e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase Acetyltransf_1 PF00583.25 PSC73671.1 - 1.2e-08 35.2 0.0 2.5e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Fer4_7 PF12838.7 PSC73671.1 - 1.1e-07 32.3 9.1 1.1e-07 32.3 9.1 3.3 3 0 0 3 3 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 PSC73671.1 - 1.6e-07 31.7 5.2 1.6e-07 31.7 5.2 2.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Acetyltransf_10 PF13673.7 PSC73671.1 - 1.8e-07 31.2 0.0 5.3e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fer4_9 PF13187.6 PSC73671.1 - 3.6e-07 30.2 8.4 3.6e-07 30.2 8.4 3.2 2 1 2 4 4 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 PSC73671.1 - 2.7e-06 28.2 6.0 0.00031 21.6 0.6 3.4 3 0 0 3 3 2 1 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 PSC73671.1 - 3.1e-06 27.2 8.8 3.1e-06 27.2 8.8 2.2 2 0 0 2 2 1 1 4Fe-4S dicluster domain zf-RING_UBOX PF13445.6 PSC73671.1 - 5.7e-06 26.2 1.8 1.3e-05 25.1 1.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Fer4_17 PF13534.6 PSC73671.1 - 1.2e-05 25.7 8.0 1.2e-05 25.7 8.0 2.7 3 0 0 3 3 1 1 4Fe-4S dicluster domain Acetyltransf_7 PF13508.7 PSC73671.1 - 1.5e-05 25.3 0.0 3.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fer4_10 PF13237.6 PSC73671.1 - 7.2e-05 22.8 4.7 0.00057 19.9 0.3 4.1 4 0 0 4 4 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 PSC73671.1 - 0.00017 21.5 3.3 0.00017 21.5 3.3 3.6 4 0 0 4 4 2 2 4Fe-4S binding domain FR47 PF08445.10 PSC73671.1 - 0.00047 20.1 0.0 0.0023 17.9 0.0 2.2 1 0 0 1 1 1 1 FR47-like protein Fer4_22 PF17179.4 PSC73671.1 - 0.0012 19.6 9.5 0.1 13.5 0.6 3.3 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 PSC73671.1 - 0.0023 17.9 2.7 0.0023 17.9 2.7 4.3 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_13 PF13370.6 PSC73671.1 - 0.0081 16.7 11.3 0.39 11.3 1.0 3.4 1 1 1 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I NTP_transf_2 PF01909.23 PSC73671.1 - 0.009 16.3 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Acetyltransf_CG PF14542.6 PSC73671.1 - 0.046 13.9 0.0 0.22 11.7 0.0 2.2 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 PSC73671.1 - 0.053 13.2 0.2 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Fer4_18 PF13746.6 PSC73671.1 - 0.38 11.0 11.8 0.45 10.7 1.9 2.9 1 1 2 3 3 3 0 4Fe-4S dicluster domain zf-RING_2 PF13639.6 PSC73671.1 - 0.96 9.8 6.4 0.2 12.0 1.5 2.5 2 0 0 2 2 2 0 Ring finger domain Fer4_4 PF12800.7 PSC73671.1 - 9.7 7.0 24.8 0.12 12.9 4.7 3.5 3 0 0 3 3 2 0 4Fe-4S binding domain Fe_hyd_lg_C PF02906.14 PSC73672.1 - 2e-86 289.6 0.5 7.6e-66 222.2 0.1 2.5 2 0 0 2 2 2 2 Iron only hydrogenase large subunit, C-terminal domain CLTH PF10607.9 PSC73672.1 - 1.6e-23 83.2 0.0 3.3e-23 82.2 0.0 1.6 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Fe_hyd_SSU PF02256.17 PSC73672.1 - 2.1e-22 78.9 0.1 3.9e-22 78.1 0.1 1.5 1 0 0 1 1 1 1 Iron hydrogenase small subunit Fer2_4 PF13510.6 PSC73672.1 - 1.9e-17 63.0 0.2 7.1e-17 61.2 0.2 2.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NADH-G_4Fe-4S_3 PF10588.9 PSC73672.1 - 5.9e-11 41.7 0.1 5.9e-11 41.7 0.1 2.6 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region Fer4 PF00037.27 PSC73672.1 - 1.3e-10 40.6 18.6 3.4e-07 29.8 3.0 3.7 3 0 0 3 3 3 2 4Fe-4S binding domain PAP_assoc PF03828.19 PSC73672.1 - 1.3e-09 38.1 0.0 2.9e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Cid1 family poly A polymerase Acetyltransf_1 PF00583.25 PSC73672.1 - 1.2e-08 35.2 0.0 2.5e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Fer4_7 PF12838.7 PSC73672.1 - 1.1e-07 32.3 9.1 1.1e-07 32.3 9.1 3.3 3 0 0 3 3 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 PSC73672.1 - 1.6e-07 31.7 5.2 1.6e-07 31.7 5.2 2.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Acetyltransf_10 PF13673.7 PSC73672.1 - 1.8e-07 31.2 0.0 5.3e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fer4_9 PF13187.6 PSC73672.1 - 3.6e-07 30.2 8.4 3.6e-07 30.2 8.4 3.2 2 1 2 4 4 2 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 PSC73672.1 - 2.7e-06 28.2 6.0 0.00031 21.6 0.6 3.4 3 0 0 3 3 2 1 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 PSC73672.1 - 3.1e-06 27.2 8.8 3.1e-06 27.2 8.8 2.2 2 0 0 2 2 1 1 4Fe-4S dicluster domain zf-RING_UBOX PF13445.6 PSC73672.1 - 5.7e-06 26.2 1.8 1.3e-05 25.1 1.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Fer4_17 PF13534.6 PSC73672.1 - 1.2e-05 25.7 8.0 1.2e-05 25.7 8.0 2.7 3 0 0 3 3 1 1 4Fe-4S dicluster domain Acetyltransf_7 PF13508.7 PSC73672.1 - 1.5e-05 25.3 0.0 3.4e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Fer4_10 PF13237.6 PSC73672.1 - 7.2e-05 22.8 4.7 0.00057 19.9 0.3 4.1 4 0 0 4 4 3 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 PSC73672.1 - 0.00017 21.5 3.3 0.00017 21.5 3.3 3.6 4 0 0 4 4 2 2 4Fe-4S binding domain FR47 PF08445.10 PSC73672.1 - 0.00047 20.1 0.0 0.0023 17.9 0.0 2.2 1 0 0 1 1 1 1 FR47-like protein Fer4_22 PF17179.4 PSC73672.1 - 0.0012 19.6 9.5 0.1 13.5 0.6 3.3 3 0 0 3 3 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.7 PSC73672.1 - 0.0023 17.9 2.7 0.0023 17.9 2.7 4.3 4 0 0 4 4 3 2 4Fe-4S binding domain Fer4_13 PF13370.6 PSC73672.1 - 0.0081 16.7 11.3 0.39 11.3 1.0 3.4 1 1 1 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I NTP_transf_2 PF01909.23 PSC73672.1 - 0.009 16.3 0.0 0.021 15.1 0.0 1.7 1 0 0 1 1 1 1 Nucleotidyltransferase domain Acetyltransf_CG PF14542.6 PSC73672.1 - 0.046 13.9 0.0 0.22 11.7 0.0 2.2 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 PSC73672.1 - 0.053 13.2 0.2 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Fer4_18 PF13746.6 PSC73672.1 - 0.38 11.0 11.8 0.45 10.7 1.9 2.9 1 1 2 3 3 3 0 4Fe-4S dicluster domain zf-RING_2 PF13639.6 PSC73672.1 - 0.96 9.8 6.4 0.2 12.1 1.5 2.5 2 0 0 2 2 2 0 Ring finger domain Fer4_4 PF12800.7 PSC73672.1 - 9.7 7.0 24.8 0.12 12.9 4.7 3.5 3 0 0 3 3 2 0 4Fe-4S binding domain Glyco_transf_90 PF05686.12 PSC73673.1 - 8.8e-31 107.2 0.1 2.9e-30 105.5 0.1 1.7 2 0 0 2 2 2 1 Glycosyl transferase family 90 WD40 PF00400.32 PSC73673.1 - 3.8e-28 97.2 6.6 7.5e-05 23.4 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ATG16 PF08614.11 PSC73673.1 - 5.1e-16 59.5 36.8 5.1e-16 59.5 36.8 1.5 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) ANAPC4_WD40 PF12894.7 PSC73673.1 - 5.6e-08 33.0 0.0 0.026 14.8 0.0 4.9 1 1 5 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Nbas_N PF15492.6 PSC73673.1 - 0.012 15.0 0.0 0.041 13.2 0.0 1.9 2 0 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Ge1_WD40 PF16529.5 PSC73673.1 - 0.014 14.4 1.4 0.087 11.8 0.0 2.7 3 1 1 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF2935 PF11155.8 PSC73673.1 - 0.032 14.6 3.9 3 8.2 3.8 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Ribonuc_2-5A PF06479.12 PSC73673.1 - 0.1 12.8 0.5 0.56 10.4 0.4 2.2 2 0 0 2 2 2 0 Ribonuclease 2-5A LMBR1 PF04791.16 PSC73673.1 - 8.3 5.2 7.6 12 4.7 7.6 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Spt4 PF06093.13 PSC73674.1 - 2.2e-30 104.6 1.4 2.7e-30 104.3 1.4 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger HIPIP PF01355.17 PSC73674.1 - 0.54 10.6 3.5 0.27 11.6 1.5 1.5 1 1 0 1 1 1 0 High potential iron-sulfur protein Mit_KHE1 PF10173.9 PSC73675.1 - 3.1e-31 108.9 0.8 6.3e-31 107.9 0.8 1.5 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Ribosomal_S8 PF00410.19 PSC73675.1 - 2e-20 73.1 0.0 3.5e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S8 POTRA_3 PF17287.2 PSC73675.1 - 0.28 10.7 0.8 0.66 9.5 0.8 1.6 1 0 0 1 1 1 0 POTRA domain Mit_KHE1 PF10173.9 PSC73676.1 - 3.1e-31 108.9 0.8 6.3e-31 107.9 0.8 1.5 1 0 0 1 1 1 1 Mitochondrial K+-H+ exchange-related Ribosomal_S8 PF00410.19 PSC73676.1 - 2e-20 73.1 0.0 3.5e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S8 POTRA_3 PF17287.2 PSC73676.1 - 0.28 10.7 0.8 0.66 9.5 0.8 1.6 1 0 0 1 1 1 0 POTRA domain WD40 PF00400.32 PSC73677.1 - 1.7e-23 82.4 17.7 4e-08 33.8 1.4 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC73677.1 - 1.2e-08 35.1 0.1 0.065 13.5 0.1 4.7 4 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF2722 PF10846.8 PSC73677.1 - 1.2 8.0 9.9 1.8 7.4 9.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 PSC73677.1 - 7 6.2 18.1 12 5.4 18.1 1.3 1 0 0 1 1 1 0 Spt20 family Sugar_tr PF00083.24 PSC73678.1 - 4.2e-32 111.6 13.2 4.3e-26 91.8 6.9 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 PSC73678.1 - 2.6e-23 82.5 45.4 3.8e-14 52.4 29.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 PSC73678.1 - 8 4.9 12.7 0.23 10.0 3.9 2.5 2 1 0 2 2 2 0 MFS/sugar transport protein MoaC PF01967.21 PSC73679.1 - 4e-50 169.4 4.1 5.5e-50 169.0 4.1 1.2 1 0 0 1 1 1 1 MoaC family DUF2722 PF10846.8 PSC73679.1 - 4.6e-05 22.6 2.1 5.7e-05 22.3 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 PSC73679.1 - 0.0011 18.6 10.4 0.0015 18.2 10.4 1.2 1 0 0 1 1 1 1 Spt20 family TFIIA PF03153.13 PSC73679.1 - 0.0027 17.8 7.9 0.0034 17.4 7.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Mlh1_C PF16413.5 PSC73679.1 - 0.66 9.3 3.2 1.5 8.2 1.9 1.8 2 0 0 2 2 2 0 DNA mismatch repair protein Mlh1 C-terminus RAB3GAP2_N PF14655.6 PSC73679.1 - 0.91 8.7 3.4 1.3 8.3 3.4 1.1 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Suf PF05843.14 PSC73679.1 - 4.6 7.2 7.0 6.8 6.6 7.0 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) LRR_8 PF13855.6 PSC73680.1 - 1.7e-05 24.5 18.6 0.027 14.3 1.1 6.8 6 1 0 7 7 7 3 Leucine rich repeat F-box-like PF12937.7 PSC73680.1 - 0.0001 22.1 0.2 0.00028 20.7 0.2 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PSC73680.1 - 0.003 17.4 0.0 0.012 15.5 0.0 2.1 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.7 PSC73680.1 - 0.0035 17.7 18.6 0.0051 17.2 1.0 6.9 8 2 2 10 10 10 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PSC73680.1 - 0.77 9.2 5.1 2.3 7.7 0.6 3.4 3 1 0 4 4 4 0 Leucine-rich repeat Ank_2 PF12796.7 PSC73681.1 - 1.1e-24 86.8 3.9 1.7e-14 54.1 0.0 2.6 1 1 2 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC73681.1 - 1.3e-19 70.3 4.5 1.3e-06 28.8 0.1 4.3 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC73681.1 - 6.1e-19 67.8 6.4 1.1e-09 38.4 0.6 3.1 2 2 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC73681.1 - 3e-14 51.7 12.0 0.01 16.3 0.0 5.9 6 0 0 6 6 6 4 Ankyrin repeat Ank PF00023.30 PSC73681.1 - 1.4e-12 47.4 24.6 4.4e-05 23.7 0.4 5.6 6 1 0 6 6 6 3 Ankyrin repeat ABC2_membrane_3 PF12698.7 PSC73682.1 - 1.4e-21 77.0 26.4 1.1e-20 74.1 25.4 2.0 2 0 0 2 2 2 1 ABC-2 family transporter protein ABC_tran PF00005.27 PSC73682.1 - 5.3e-21 75.6 0.0 8.3e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 PSC73682.1 - 2.1e-09 37.6 0.1 2.8e-05 24.1 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 PSC73682.1 - 1.6e-05 24.4 29.7 0.00052 19.5 22.8 2.4 2 0 0 2 2 2 2 ABC-2 type transporter AAA_23 PF13476.6 PSC73682.1 - 0.00024 21.7 0.2 0.00044 20.8 0.2 1.3 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 PSC73682.1 - 0.024 14.4 0.0 0.07 12.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC2_membrane_2 PF12679.7 PSC73682.1 - 8.4 5.6 26.3 1.9 7.7 22.4 2.0 2 1 0 2 2 2 0 ABC-2 family transporter protein RRM_1 PF00076.22 PSC73683.1 - 4.2e-13 48.9 0.0 7.2e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 PSC73683.1 - 5.9e-07 30.2 0.0 5.9e-07 30.2 0.0 1.8 2 0 0 2 2 2 1 Torus domain zf_CCCH_4 PF18345.1 PSC73683.1 - 4.6e-06 26.5 2.4 9.8e-06 25.5 2.4 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 PSC73683.1 - 0.00062 19.6 2.3 0.00062 19.6 2.3 2.4 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 PSC73683.1 - 0.0047 17.1 0.1 0.0096 16.1 0.1 1.5 1 0 0 1 1 1 1 Zinc-finger containing family RRM_7 PF16367.5 PSC73683.1 - 0.011 15.8 0.0 0.028 14.6 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif RRM_3 PF08777.11 PSC73683.1 - 0.017 15.1 0.0 0.017 15.1 0.0 1.9 2 0 0 2 2 2 0 RNA binding motif zf-CCCH_4 PF18044.1 PSC73683.1 - 0.018 14.8 2.7 0.045 13.6 2.7 1.7 1 0 0 1 1 1 0 CCCH-type zinc finger zf-CCCH_2 PF14608.6 PSC73683.1 - 0.065 13.7 2.1 0.12 12.9 2.1 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger DUF2838 PF10998.8 PSC73684.1 - 1.1e-35 122.2 7.6 1.1e-35 122.2 7.6 2.7 2 1 1 3 3 3 1 Protein of unknown function (DUF2838) AAR2 PF05282.11 PSC73685.1 - 3.1e-86 289.9 0.0 3.6e-86 289.7 0.0 1.0 1 0 0 1 1 1 1 AAR2 protein Xpo1 PF08389.12 PSC73686.1 - 1.4e-16 60.9 0.0 3.7e-16 59.5 0.0 1.8 1 0 0 1 1 1 1 Exportin 1-like protein Suf PF05843.14 PSC73688.1 - 3.4e-49 168.4 11.9 1.3e-46 159.9 0.0 4.1 3 1 0 3 3 3 2 Suppressor of forked protein (Suf) NRDE-2 PF08424.10 PSC73688.1 - 1.4e-05 24.4 0.2 0.25 10.4 0.3 5.1 3 2 1 4 4 4 1 NRDE-2, necessary for RNA interference DUF2457 PF10446.9 PSC73688.1 - 0.59 9.2 22.8 0.028 13.6 11.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) TFIIA PF03153.13 PSC73688.1 - 1.6 8.6 14.9 3 7.8 14.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FlgM PF04316.13 PSC73688.1 - 5.2 7.5 7.6 0.58 10.6 0.1 3.4 2 1 0 2 2 2 0 Anti-sigma-28 factor, FlgM WAC_Acf1_DNA_bd PF10537.9 PSC73690.1 - 1.9e-25 89.3 0.1 4.6e-25 88.1 0.1 1.7 1 0 0 1 1 1 1 ATP-utilising chromatin assembly and remodelling N-terminal PHD PF00628.29 PSC73690.1 - 2.8e-11 43.1 20.2 8.3e-10 38.4 5.8 2.7 2 0 0 2 2 2 2 PHD-finger Methyltransf_16 PF10294.9 PSC73690.1 - 3.1e-10 40.0 0.0 3.8e-08 33.2 0.1 2.4 2 0 0 2 2 2 1 Lysine methyltransferase WSD PF15613.6 PSC73690.1 - 1.6e-09 38.1 2.9 4.5e-09 36.7 0.4 2.8 2 1 0 2 2 2 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif EamA PF00892.20 PSC73690.1 - 5.2e-09 36.4 27.9 9.5e-05 22.6 15.7 2.3 2 0 0 2 2 2 2 EamA-like transporter family PHD_2 PF13831.6 PSC73690.1 - 6.4e-06 25.6 13.4 1.3e-05 24.6 0.6 3.1 3 0 0 3 3 3 2 PHD-finger zf-PHD-like PF15446.6 PSC73690.1 - 0.0013 18.4 1.2 0.0013 18.4 1.2 2.7 2 1 0 2 2 2 1 PHD/FYVE-zinc-finger like domain Arm PF00514.23 PSC73690.1 - 0.1 12.7 0.0 0.35 11.0 0.0 2.0 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat zf-HC5HC2H PF13771.6 PSC73690.1 - 0.58 10.4 9.4 2.9 8.2 3.8 2.5 2 0 0 2 2 2 0 PHD-like zinc-binding domain F-box-like PF12937.7 PSC73691.1 - 0.067 13.1 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 F-box-like DUF4179 PF13786.6 PSC73692.1 - 0.5 10.9 1.9 9.2 6.8 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) Defensin_propep PF00879.18 PSC73692.1 - 1.9 8.8 10.6 4.8 7.5 2.2 2.4 2 0 0 2 2 2 0 Defensin propeptide TPT PF03151.16 PSC73693.1 - 8.7e-25 87.6 19.4 1.1e-24 87.3 19.4 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 PSC73693.1 - 4.7e-07 29.3 21.6 2.8e-06 26.7 21.5 2.7 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.20 PSC73693.1 - 0.009 16.2 35.1 0.065 13.4 17.5 2.1 2 0 0 2 2 2 2 EamA-like transporter family Thy1 PF02511.15 PSC73694.1 - 0.083 12.7 0.0 1.1 9.0 0.0 2.1 2 0 0 2 2 2 0 Thymidylate synthase complementing protein CD36 PF01130.21 PSC73695.1 - 2.7e-61 207.5 0.0 3.6e-61 207.1 0.0 1.0 1 0 0 1 1 1 1 CD36 family Glyco_hydro_20 PF00728.22 PSC73696.1 - 1.3e-85 287.9 0.5 1.8e-69 234.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 PSC73696.1 - 7.6e-15 55.8 0.0 2.1e-14 54.3 0.0 1.8 2 1 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 PSC73696.1 - 0.013 16.3 0.6 0.055 14.3 0.0 2.4 2 1 0 2 2 2 0 Glycosyl hydrolase family 20, domain 2 PGA2 PF07543.12 PSC73696.1 - 2.6 8.0 5.4 2.6 8.0 0.5 2.4 2 0 0 2 2 2 0 Protein trafficking PGA2 Ferritin_2 PF13668.6 PSC73697.1 - 1.4e-07 31.8 0.0 2.4e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 Ferritin-like domain Caleosin PF05042.13 PSC73699.1 - 1.1e-67 227.3 0.2 1.6e-67 226.7 0.2 1.2 1 0 0 1 1 1 1 Caleosin related protein Pur_ac_phosph_N PF16656.5 PSC73699.1 - 2.1e-19 69.8 0.0 5.8e-19 68.5 0.0 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 PSC73699.1 - 7.9e-15 55.9 0.4 1.8e-14 54.7 0.1 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase fn3_PAP PF17808.1 PSC73699.1 - 8.7e-14 51.7 0.0 1.2e-12 48.0 0.0 2.3 1 1 0 1 1 1 1 Fn3-like domain from Purple Acid Phosphatase Metallophos_C PF14008.6 PSC73699.1 - 4.6e-05 24.2 0.2 0.00012 22.9 0.2 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C EF-hand_6 PF13405.6 PSC73699.1 - 0.0072 16.2 0.6 0.071 13.1 0.1 2.4 2 0 0 2 2 2 1 EF-hand domain UPF0014 PF03649.13 PSC73699.1 - 0.16 11.3 0.6 0.27 10.5 0.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0014) EF-hand_1 PF00036.32 PSC73699.1 - 0.3 10.7 0.7 2.9 7.6 0.1 2.3 2 0 0 2 2 2 0 EF hand Pan3_PK PF18101.1 PSC73700.1 - 1.1e-48 164.7 0.0 1.5e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 PSC73700.1 - 0.0024 17.3 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PAM2 PF07145.15 PSC73700.1 - 1.5 8.7 17.4 8.5 6.3 0.1 5.8 5 1 0 5 5 5 0 Ataxin-2 C-terminal region rve PF00665.26 PSC73701.1 - 1.7e-18 67.0 0.0 3.7e-18 65.8 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Aldedh PF00171.22 PSC73701.1 - 7.3e-13 47.8 0.0 1.2e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Aldehyde dehydrogenase family rve_3 PF13683.6 PSC73701.1 - 0.013 15.3 0.0 0.035 13.9 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain PAS_9 PF13426.7 PSC73702.1 - 5.4e-50 168.0 0.0 4.4e-24 84.7 0.0 4.3 4 0 0 4 4 4 3 PAS domain PAS_4 PF08448.10 PSC73702.1 - 1.7e-30 105.5 5.3 1.4e-09 38.2 0.2 5.0 4 1 0 4 4 4 3 PAS fold PAS PF00989.25 PSC73702.1 - 1.8e-29 102.0 0.0 9.8e-10 38.4 0.0 4.4 4 0 0 4 4 4 3 PAS fold HATPase_c PF02518.26 PSC73702.1 - 1.2e-27 96.6 0.0 3.3e-27 95.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 PSC73702.1 - 2e-19 69.8 0.1 4.5e-19 68.7 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 PSC73702.1 - 9.2e-18 64.1 0.3 3.1e-17 62.4 0.2 2.1 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 PSC73702.1 - 3.1e-16 59.4 0.0 3.6e-07 30.4 0.0 2.8 2 0 0 2 2 2 2 PAS fold PAS_8 PF13188.7 PSC73702.1 - 4.2e-16 58.5 0.0 0.00029 20.8 0.0 4.6 4 0 0 4 4 4 3 PAS domain PAS_7 PF12860.7 PSC73702.1 - 0.044 14.0 0.0 24 5.1 0.0 3.9 4 0 0 4 4 4 0 PAS fold ADH_zinc_N_2 PF13602.6 PSC73703.1 - 7e-29 101.6 0.1 1.3e-28 100.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 PSC73703.1 - 7.9e-17 61.5 0.6 1.3e-16 60.7 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PSC73704.1 - 7e-29 101.6 0.1 1.3e-28 100.7 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 PSC73704.1 - 7.9e-17 61.5 0.6 1.3e-16 60.7 0.6 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase BCDHK_Adom3 PF10436.9 PSC73705.1 - 1.4e-59 200.6 0.0 1.8e-59 200.2 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 PSC73705.1 - 8.3e-14 52.0 0.0 1.7e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PSC73705.1 - 0.0011 18.9 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase BCDHK_Adom3 PF10436.9 PSC73706.1 - 4.4e-59 198.9 0.0 6.1e-59 198.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase HATPase_c PF02518.26 PSC73706.1 - 8.6e-14 52.0 0.0 1.7e-13 51.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PSC73706.1 - 0.0011 18.8 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ATP-synt_G PF04718.15 PSC73707.1 - 1.9e-13 51.1 0.0 2.5e-13 50.7 0.0 1.4 1 1 0 1 1 1 1 Mitochondrial ATP synthase g subunit DUF2462 PF09495.10 PSC73708.1 - 2.5e-08 34.5 12.5 2.5e-08 34.5 12.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2462) Tom37 PF10568.9 PSC73709.1 - 3e-29 101.9 0.0 7.3e-29 100.6 0.0 1.7 2 0 0 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_4 PF17172.4 PSC73709.1 - 4.6e-17 62.6 0.0 2e-16 60.5 0.0 2.1 2 1 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 PSC73709.1 - 1.9e-09 37.1 0.0 3.7e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PSC73709.1 - 4.6e-08 33.0 1.7 9.4e-08 32.0 0.3 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Cystatin PF00031.21 PSC73710.1 - 0.0095 16.2 0.1 2.6 8.4 0.0 3.2 3 0 0 3 3 3 1 Cystatin domain Cystatin PF00031.21 PSC73711.1 - 0.0058 16.9 0.1 2.2 8.6 0.0 3.3 3 0 0 3 3 3 1 Cystatin domain ARS2 PF04959.13 PSC73712.1 - 2.1e-12 47.9 0.6 2.1e-12 47.9 0.6 2.7 2 1 0 3 3 3 1 Arsenite-resistance protein 2 DUF3546 PF12066.8 PSC73712.1 - 9.2e-06 25.8 0.0 9.2e-06 25.8 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3546) SBP PF03110.14 PSC73713.1 - 6.8e-25 87.2 2.1 1.6e-24 86.0 2.1 1.7 1 0 0 1 1 1 1 SBP domain cNMP_binding PF00027.29 PSC73713.1 - 8.7e-11 41.7 0.0 1.7e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 PSC73713.1 - 0.00053 19.3 1.0 0.00084 18.6 1.0 1.2 1 0 0 1 1 1 1 Ion transport protein SUIM_assoc PF16619.5 PSC73713.1 - 0.0061 16.6 0.7 0.0061 16.6 0.7 3.5 3 0 0 3 3 3 2 Unstructured region C-term to UIM in Ataxin3 Trimer_CC PF08954.11 PSC73713.1 - 0.072 12.7 1.0 0.33 10.6 1.0 2.1 1 0 0 1 1 1 0 Trimerisation motif GCD14 PF08704.10 PSC73714.1 - 1.7e-90 303.0 0.0 3.2e-89 298.8 0.0 2.0 1 1 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.6 PSC73714.1 - 6e-11 42.4 0.0 9.5e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC73714.1 - 2.6e-07 31.3 0.3 6.6e-07 29.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 PSC73714.1 - 7.4e-06 25.9 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 PSC73714.1 - 4.3e-05 24.1 0.0 0.00014 22.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 PSC73714.1 - 0.00055 20.9 0.0 0.0015 19.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.20 PSC73714.1 - 0.011 14.9 0.0 0.016 14.3 0.0 1.1 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 PSC73714.1 - 0.02 15.6 0.0 0.059 14.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain Striatin PF08232.12 PSC73714.1 - 0.037 14.6 2.3 0.058 14.0 2.3 1.2 1 0 0 1 1 1 0 Striatin family Methyltransf_23 PF13489.6 PSC73714.1 - 0.045 13.6 0.4 0.11 12.4 0.4 1.9 1 1 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 PSC73714.1 - 0.081 12.2 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltr_RsmB-F PF01189.17 PSC73714.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.5 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F RPE65 PF03055.15 PSC73715.1 - 7.2e-108 361.7 0.0 8.3e-108 361.5 0.0 1.0 1 0 0 1 1 1 1 Retinal pigment epithelial membrane protein HSP70 PF00012.20 PSC73716.1 - 3.3e-269 894.2 9.3 3.8e-269 894.0 9.3 1.0 1 0 0 1 1 1 1 Hsp70 protein CHRD PF07452.12 PSC73716.1 - 1.2e-19 71.4 0.9 6.3e-19 69.1 0.4 2.4 2 0 0 2 2 2 1 CHRD domain MreB_Mbl PF06723.13 PSC73716.1 - 1.5e-14 53.6 0.2 8.1e-12 44.6 0.0 2.7 2 1 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 PSC73716.1 - 9.3e-05 22.8 0.9 0.49 10.8 0.0 3.8 3 2 0 3 3 3 2 Cell division protein FtsA FGGY_C PF02782.16 PSC73716.1 - 0.00048 19.9 0.0 0.0014 18.4 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain DUF4363 PF14276.6 PSC73716.1 - 0.31 11.2 3.2 0.69 10.1 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4363) Bin3 PF06859.12 PSC73717.1 - 7.6e-28 97.3 0.0 1.6e-27 96.2 0.0 1.6 1 0 0 1 1 1 1 Bicoid-interacting protein 3 (Bin3) Methyltransf_25 PF13649.6 PSC73717.1 - 1.9e-07 31.7 0.0 0.0021 18.7 0.1 3.8 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_12 PF08242.12 PSC73717.1 - 3.9e-07 30.8 1.9 3.2e-06 27.8 0.0 3.5 5 1 0 5 5 5 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC73717.1 - 9.2e-07 28.8 0.0 9.2e-07 28.8 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC73717.1 - 6.4e-06 26.7 0.0 0.0001 22.9 0.1 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC73717.1 - 0.00017 21.4 0.0 0.023 14.5 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 PSC73717.1 - 0.0096 15.9 0.0 0.021 14.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain RRM_1 PF00076.22 PSC73718.1 - 4e-11 42.6 0.0 8e-06 25.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PGAP1 PF07819.13 PSC73719.1 - 4.3e-23 82.2 0.0 2.7e-22 79.6 0.0 2.0 1 1 0 1 1 1 1 PGAP1-like protein bZIP_1 PF00170.21 PSC73719.1 - 2.8e-06 27.3 8.4 4.7e-06 26.6 8.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor DUF676 PF05057.14 PSC73719.1 - 0.00032 20.3 0.0 0.008 15.7 0.0 2.1 2 0 0 2 2 2 1 Putative serine esterase (DUF676) bZIP_2 PF07716.15 PSC73719.1 - 0.00035 20.6 10.5 0.00093 19.2 10.5 1.7 1 1 0 1 1 1 1 Basic region leucine zipper Palm_thioest PF02089.15 PSC73719.1 - 0.2 11.4 0.0 0.32 10.8 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase E2F_CC-MB PF16421.5 PSC73721.1 - 3.9e-17 62.4 0.0 5.6e-17 61.9 0.0 1.2 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 PSC73721.1 - 2.5e-14 53.1 0.0 5.4e-14 52.0 0.0 1.5 2 0 0 2 2 2 1 E2F/DP family winged-helix DNA-binding domain DUF2244 PF10003.9 PSC73721.1 - 0.028 14.1 0.1 0.044 13.5 0.1 1.2 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) adh_short PF00106.25 PSC73722.1 - 7.2e-32 110.4 0.2 9.3e-32 110.1 0.2 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC73722.1 - 8.4e-24 84.4 1.1 1.3e-23 83.8 1.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC73722.1 - 0.0039 17.1 0.2 0.0062 16.5 0.2 1.5 1 1 0 1 1 1 1 KR domain Glyco_tran_WecB PF03808.13 PSC73722.1 - 0.0051 16.8 0.0 0.013 15.5 0.0 1.6 1 1 0 1 1 1 1 Glycosyl transferase WecB/TagA/CpsF family Chloroa_b-bind PF00504.21 PSC73724.1 - 3.5e-46 157.7 0.1 5e-46 157.2 0.1 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein MutS_V PF00488.21 PSC73725.1 - 1.3e-59 201.4 0.8 1.3e-49 168.8 0.0 2.3 2 0 0 2 2 2 2 MutS domain V MutS_III PF05192.18 PSC73725.1 - 1.8e-33 116.4 0.0 3.4e-33 115.5 0.0 1.5 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.20 PSC73725.1 - 3.7e-23 81.9 0.0 6.6e-23 81.1 0.0 1.4 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 PSC73725.1 - 1.1e-05 25.8 0.0 3.2e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 PSC73725.1 - 0.0008 19.7 0.0 0.0014 18.9 0.0 1.4 1 0 0 1 1 1 1 MutS family domain IV Caleosin PF05042.13 PSC73726.1 - 3e-70 235.6 0.5 4.6e-69 231.7 0.5 2.0 1 1 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 PSC73726.1 - 0.00083 19.1 1.1 0.0065 16.3 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 PSC73726.1 - 0.001 18.4 1.4 0.012 15.1 0.2 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 PSC73726.1 - 0.042 14.3 0.1 0.15 12.5 0.1 1.9 1 1 0 1 1 1 0 EF-hand domain pair Caleosin PF05042.13 PSC73727.1 - 3.2e-73 245.2 0.1 4e-73 244.9 0.1 1.1 1 0 0 1 1 1 1 Caleosin related protein EF-hand_6 PF13405.6 PSC73727.1 - 0.00073 19.3 1.1 0.0061 16.4 0.2 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 PSC73727.1 - 0.0009 18.6 1.4 0.011 15.2 0.2 2.3 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 PSC73727.1 - 0.037 14.5 0.1 0.14 12.7 0.1 1.9 1 1 0 1 1 1 0 EF-hand domain pair Pkinase PF00069.25 PSC73728.1 - 6.5e-48 163.4 0.0 8.7e-48 163.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73728.1 - 1.1e-18 67.4 0.0 2.1e-18 66.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase mTERF PF02536.14 PSC73728.1 - 3.8e-06 26.1 0.0 0.00032 19.7 0.0 2.3 2 1 0 2 2 2 2 mTERF Pkinase_fungal PF17667.1 PSC73728.1 - 0.087 11.6 0.0 0.72 8.6 0.0 2.0 2 0 0 2 2 2 0 Fungal protein kinase zf-C3HC4_3 PF13920.6 PSC73729.1 - 2.1e-12 46.7 9.4 4.7e-12 45.6 9.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC73729.1 - 0.00043 20.6 11.8 0.00081 19.7 11.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PSC73729.1 - 0.00044 20.1 12.8 0.00076 19.3 12.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PSC73729.1 - 0.0015 18.3 10.9 0.003 17.4 10.9 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Aldo_ket_red PF00248.21 PSC73729.1 - 0.088 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 Aldo/keto reductase family zf-RING_4 PF14570.6 PSC73729.1 - 0.15 11.9 8.2 0.27 11.1 8.2 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 PSC73729.1 - 6.1 6.9 8.5 14 5.7 8.5 1.7 1 0 0 1 1 1 0 zinc-RING finger domain AAA_25 PF13481.6 PSC73730.1 - 3.7e-14 52.8 0.1 6.3e-07 29.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain Lon_C PF05362.13 PSC73730.1 - 8.1e-10 38.6 1.0 1.2e-09 38.0 0.1 1.6 2 0 0 2 2 2 1 Lon protease (S16) C-terminal proteolytic domain Rubredoxin_2 PF18073.1 PSC73730.1 - 1e-09 37.9 7.8 2e-09 37.0 7.8 1.5 1 0 0 1 1 1 1 Rubredoxin metal binding domain ATPase PF06745.13 PSC73730.1 - 1.8e-09 37.3 1.1 0.00012 21.5 0.1 3.1 2 1 0 2 2 2 2 KaiC ChlI PF13541.6 PSC73730.1 - 7.8e-09 35.4 0.1 2e-08 34.1 0.0 1.6 2 0 0 2 2 2 1 Subunit ChlI of Mg-chelatase DnaB_C PF03796.15 PSC73730.1 - 0.0011 18.4 0.2 0.15 11.4 0.0 2.5 3 0 0 3 3 3 1 DnaB-like helicase C terminal domain AAA_16 PF13191.6 PSC73730.1 - 0.0019 18.6 1.1 0.0038 17.6 1.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain Rad51 PF08423.11 PSC73730.1 - 0.003 16.9 0.2 0.078 12.2 0.0 2.3 2 0 0 2 2 2 1 Rad51 AAA_22 PF13401.6 PSC73730.1 - 0.0058 16.9 0.2 0.081 13.2 0.1 2.4 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 PSC73730.1 - 0.028 14.3 0.0 0.088 12.7 0.0 1.8 1 0 0 1 1 1 0 NTPase NACHT PF05729.12 PSC73730.1 - 0.05 13.5 0.0 0.087 12.7 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 PSC73730.1 - 0.059 13.4 0.1 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA PF00004.29 PSC73730.1 - 0.069 13.6 0.0 0.31 11.5 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 PSC73730.1 - 0.11 13.0 0.1 0.35 11.4 0.1 1.9 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 PSC73730.1 - 0.18 11.6 0.2 0.48 10.2 0.2 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 PSC73730.1 - 0.28 11.1 0.7 0.53 10.2 0.7 1.4 1 0 0 1 1 1 0 RsgA GTPase ATP11 PF06644.11 PSC73731.1 - 1.6e-32 113.4 0.1 2e-32 113.1 0.1 1.1 1 0 0 1 1 1 1 ATP11 protein Pox_A28 PF04584.14 PSC73731.1 - 0.062 13.5 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Poxvirus A28 family Peptidase_C14 PF00656.22 PSC73732.1 - 7.1e-49 167.0 0.0 9.1e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain LCIB_C_CA PF18599.1 PSC73732.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Peptidase_C14 PF00656.22 PSC73733.1 - 7.3e-49 167.0 0.0 9.3e-49 166.6 0.0 1.1 1 0 0 1 1 1 1 Caspase domain LCIB_C_CA PF18599.1 PSC73733.1 - 0.11 11.7 0.0 0.22 10.8 0.0 1.4 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Haem_degrading PF03928.14 PSC73734.1 - 0.055 13.5 0.5 0.14 12.2 0.5 1.7 1 0 0 1 1 1 0 Haem-degrading BTB PF00651.31 PSC73734.1 - 0.13 12.5 0.2 0.26 11.5 0.2 1.4 1 0 0 1 1 1 0 BTB/POZ domain Rhomboid PF01694.22 PSC73735.1 - 3.4e-34 118.0 3.5 5.1e-34 117.4 3.5 1.3 1 0 0 1 1 1 1 Rhomboid family CoaE PF01121.20 PSC73736.1 - 1.9e-15 57.0 0.0 2.5e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Dephospho-CoA kinase SlyX PF04102.12 PSC73736.1 - 0.091 13.4 0.1 0.18 12.5 0.1 1.4 1 0 0 1 1 1 0 SlyX DUF5324 PF17258.2 PSC73736.1 - 0.22 11.2 8.2 0.37 10.4 8.2 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5324) Aminotran_1_2 PF00155.21 PSC73737.1 - 1.5e-38 132.9 0.0 2.4e-38 132.3 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 PSC73737.1 - 3.2e-06 26.3 0.0 0.00022 20.2 0.0 2.1 2 0 0 2 2 2 2 Allinase LCIB_C_CA PF18599.1 PSC73738.1 - 1.2e-74 250.4 0.0 1.9e-74 249.7 0.0 1.3 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Pkinase_Tyr PF07714.17 PSC73738.1 - 1.7e-39 135.7 0.0 4.3e-39 134.4 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC73738.1 - 1.5e-38 132.7 0.0 2.7e-38 131.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain PAN_4 PF14295.6 PSC73738.1 - 2e-08 34.0 14.5 0.0049 16.8 1.5 3.6 3 0 0 3 3 3 3 PAN domain LCIB_C_CA PF18599.1 PSC73739.1 - 1.2e-74 250.3 0.0 1.9e-74 249.7 0.0 1.3 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Pkinase PF00069.25 PSC73739.1 - 6.5e-45 153.5 0.0 1.2e-44 152.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73739.1 - 1.1e-43 149.4 0.0 2.7e-43 148.1 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase PAN_4 PF14295.6 PSC73739.1 - 2e-08 34.0 14.5 0.0049 16.7 1.5 3.6 3 0 0 3 3 3 3 PAN domain Kdo PF06293.14 PSC73739.1 - 0.013 14.8 0.1 0.025 13.9 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1499 PF07386.11 PSC73740.1 - 0.062 13.8 0.0 0.081 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1499) TMEM234 PF10639.9 PSC73741.1 - 1.1e-15 57.7 0.0 2e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Putative transmembrane family 234 FAD_binding_4 PF01565.23 PSC73742.1 - 3.8e-12 46.1 0.1 8e-11 41.8 0.0 2.5 2 0 0 2 2 2 1 FAD binding domain ALO PF04030.14 PSC73742.1 - 6.1e-12 45.9 0.1 2.2e-10 40.8 0.0 2.1 2 0 0 2 2 2 2 D-arabinono-1,4-lactone oxidase Apolipoprotein PF01442.18 PSC73743.1 - 5.8e-12 45.9 30.8 6.9e-06 26.1 12.7 2.1 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 PSC73743.1 - 1e-09 38.9 48.9 0.00061 20.3 5.0 5.9 2 2 4 6 6 6 6 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 PSC73743.1 - 2.9e-08 34.1 45.5 0.48 11.0 2.8 6.3 2 2 2 4 4 4 3 YtxH-like protein ApoLp-III PF07464.11 PSC73743.1 - 1.4e-05 25.2 20.1 0.011 15.9 7.0 3.1 1 1 2 3 3 3 3 Apolipophorin-III precursor (apoLp-III) CdvA PF18822.1 PSC73743.1 - 0.0049 16.7 6.0 20 5.0 0.1 4.2 2 2 1 4 4 4 0 CdvA-like coiled-coil domain Tape_meas_lam_C PF09718.10 PSC73743.1 - 0.19 11.9 19.1 2.1 8.5 1.0 5.0 3 2 2 5 5 5 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ApoO PF09769.9 PSC73743.1 - 0.31 11.0 6.4 19 5.2 0.1 3.9 2 2 2 4 4 4 0 Apolipoprotein O HisKA_3 PF07730.13 PSC73743.1 - 0.63 10.6 18.7 21 5.7 0.1 6.1 2 2 2 4 4 4 0 Histidine kinase FH2 PF02181.23 PSC73743.1 - 1 8.4 5.4 8.7 5.4 0.2 2.8 2 1 1 3 3 3 0 Formin Homology 2 Domain FTR_C PF02741.15 PSC73743.1 - 1.1 9.3 7.5 0.19 11.7 0.3 2.7 3 0 0 3 3 3 0 FTR, proximal lobe REF PF05755.12 PSC73743.1 - 1.2 8.9 28.0 0.096 12.5 3.0 4.1 1 1 2 4 4 4 0 Rubber elongation factor protein (REF) Apo-CIII PF05778.12 PSC73743.1 - 2.6 7.8 13.7 5 6.8 0.2 4.6 4 1 1 5 5 5 0 Apolipoprotein CIII (Apo-CIII) DUF948 PF06103.11 PSC73743.1 - 3.3 8.0 17.6 6.2 7.2 0.7 4.2 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) Chlorosome_CsmC PF11098.8 PSC73743.1 - 4.3 7.3 36.4 0.14 12.2 6.0 4.8 1 1 5 6 6 6 0 Chlorosome envelope protein C DUF725 PF05267.12 PSC73743.1 - 4.7 7.2 6.1 17 5.4 0.1 3.3 2 2 1 3 3 3 0 Protein of unknown function (DUF725) Sortilin-Vps10 PF15902.5 PSC73744.1 - 4e-63 213.8 0.0 5.7e-63 213.2 0.0 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 PSC73744.1 - 2.5e-19 70.2 1.7 4.6e-19 69.4 1.7 1.3 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal GRP PF07172.11 PSC73744.1 - 0.039 14.6 11.9 0.15 12.8 11.9 2.0 1 0 0 1 1 1 0 Glycine rich protein family BNR_6 PF15899.5 PSC73744.1 - 0.047 13.8 0.1 8.9 6.7 0.0 3.4 4 0 0 4 4 4 0 BNR-Asp box repeat BNR PF02012.20 PSC73744.1 - 0.11 12.5 4.5 10 6.6 0.0 4.7 5 0 0 5 5 5 0 BNR/Asp-box repeat NIF PF03031.18 PSC73745.1 - 1.9e-05 24.4 0.0 3.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Atg14 PF10186.9 PSC73745.1 - 0.00097 18.3 4.5 0.0011 18.2 0.0 2.4 3 0 0 3 3 3 1 Vacuolar sorting 38 and autophagy-related subunit 14 Suf PF05843.14 PSC73745.1 - 9.3 6.1 11.3 15 5.4 11.3 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Catalase PF00199.19 PSC73747.1 - 3e-174 579.6 0.0 3.4e-174 579.4 0.0 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 PSC73747.1 - 1.1e-14 54.3 0.0 3.9e-14 52.6 0.0 1.9 2 0 0 2 2 2 1 Catalase-related immune-responsive Glyco_hydro_77 PF02446.17 PSC73748.1 - 7.6e-151 503.1 0.1 1e-150 502.7 0.1 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 PSC73748.1 - 1e-26 92.6 0.0 6.6e-12 45.2 0.0 2.5 2 0 0 2 2 2 2 Starch binding domain Methyltransf_11 PF08241.12 PSC73749.1 - 4.3e-07 30.5 3.1 6.1e-07 30.0 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC73749.1 - 3.8e-05 24.3 0.0 3.8e-05 24.3 0.0 3.5 5 0 0 5 5 2 1 Methyltransferase domain TFIIA PF03153.13 PSC73749.1 - 0.0024 17.9 23.0 0.0024 17.9 23.0 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Methyltransf_12 PF08242.12 PSC73749.1 - 0.0068 17.1 3.7 0.044 14.5 0.0 3.2 2 1 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC73749.1 - 0.008 16.0 0.1 0.4 10.5 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Neur_chan_memb PF02932.16 PSC73749.1 - 0.039 14.0 2.0 0.076 13.1 2.0 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.17 PSC73749.1 - 0.05 13.8 2.3 0.09 12.9 2.3 1.4 1 0 0 1 1 1 0 DDHD domain SpoIIP PF07454.11 PSC73749.1 - 0.11 11.9 6.2 0.17 11.3 6.2 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Eapp_C PF10238.9 PSC73749.1 - 0.13 12.3 6.4 0.26 11.4 6.4 1.4 1 0 0 1 1 1 0 E2F-associated phosphoprotein MMR1 PF08505.10 PSC73749.1 - 0.14 12.5 7.0 0.21 11.8 7.0 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Presenilin PF01080.17 PSC73749.1 - 0.26 10.0 6.6 0.38 9.5 6.6 1.1 1 0 0 1 1 1 0 Presenilin FAM150 PF15129.6 PSC73749.1 - 0.43 10.7 4.0 1 9.5 4.0 1.6 1 0 0 1 1 1 0 FAM150 family PAT1 PF09770.9 PSC73749.1 - 0.96 7.6 17.7 0.017 13.4 11.1 1.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 PSC73749.1 - 1.5 8.6 7.1 2.3 8.0 7.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Rpp20 PF12328.8 PSC73749.1 - 1.8 8.5 7.2 4.3 7.3 7.2 1.6 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Plasmodium_Vir PF05795.11 PSC73749.1 - 2 7.8 2.9 3.3 7.0 2.9 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein EPL1 PF10513.9 PSC73749.1 - 2.3 8.6 7.4 4.1 7.8 7.4 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like MCU PF04678.13 PSC73749.1 - 2.4 8.2 5.5 4.8 7.2 5.5 1.4 1 0 0 1 1 1 0 Mitochondrial calcium uniporter DUF3408 PF11888.8 PSC73749.1 - 2.5 8.2 8.6 4.4 7.4 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) DUF775 PF05603.12 PSC73749.1 - 4 6.9 9.3 8.2 5.9 9.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF775) Connexin PF00029.19 PSC73749.1 - 4.6 6.9 4.7 7.1 6.3 4.7 1.2 1 0 0 1 1 1 0 Connexin Spt20 PF12090.8 PSC73749.1 - 5.4 6.6 30.7 9.7 5.7 30.7 1.3 1 0 0 1 1 1 0 Spt20 family Sec62 PF03839.16 PSC73749.1 - 5.5 6.4 5.0 8.2 5.9 5.0 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Hid1 PF12722.7 PSC73749.1 - 8.2 4.4 6.1 11 4.0 6.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ndc1_Nup PF09531.10 PSC73749.1 - 8.3 5.0 5.7 12 4.4 5.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Exonuc_VII_L PF02601.15 PSC73751.1 - 0.0011 18.6 5.9 0.0018 17.9 5.9 1.3 1 0 0 1 1 1 1 Exonuclease VII, large subunit DDHD PF02862.17 PSC73751.1 - 1 9.5 3.6 1.9 8.6 3.6 1.4 1 0 0 1 1 1 0 DDHD domain Phage_GPO PF05929.11 PSC73751.1 - 1.8 8.1 10.3 2.9 7.4 10.3 1.2 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Folliculin PF11704.8 PSC73751.1 - 2.2 8.1 7.9 4.3 7.2 7.9 1.4 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF3552 PF12072.8 PSC73751.1 - 3.4 7.0 20.3 6.1 6.2 20.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3552) FapA PF03961.13 PSC73751.1 - 4.3 5.8 5.4 6.1 5.3 5.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A HemX PF04375.14 PSC73751.1 - 4.6 6.4 31.5 7.7 5.7 30.9 1.6 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4407 PF14362.6 PSC73751.1 - 8 5.7 15.8 17 4.6 15.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Trypsin PF00089.26 PSC73752.1 - 3.6e-35 121.8 0.0 6e-35 121.1 0.0 1.4 1 1 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PSC73752.1 - 2.5e-06 28.4 0.1 3.6e-05 24.7 0.0 2.4 1 1 1 2 2 2 1 Trypsin-like peptidase domain TIP49 PF06068.13 PSC73753.1 - 1e-169 564.3 0.0 2e-169 563.4 0.0 1.4 2 0 0 2 2 2 1 TIP49 P-loop domain TIP49_C PF17856.1 PSC73753.1 - 1.3e-20 73.3 0.0 3.4e-20 71.9 0.0 1.8 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 PSC73753.1 - 9.7e-11 42.2 0.1 1e-06 29.2 0.1 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PSC73753.1 - 1.5e-10 41.0 0.1 3.9e-07 29.9 0.0 2.4 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PSC73753.1 - 3e-06 27.5 0.2 0.042 14.1 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 PSC73753.1 - 9.2e-06 26.1 0.1 0.0013 19.1 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 PSC73753.1 - 0.0004 20.4 0.1 0.073 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 PSC73753.1 - 0.00089 19.6 0.5 0.43 10.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.6 PSC73753.1 - 0.0015 18.8 0.0 0.0034 17.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PSC73753.1 - 0.0034 17.6 0.0 0.13 12.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 PSC73753.1 - 0.0047 16.5 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 PSC73753.1 - 0.0077 15.6 0.2 0.31 10.4 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 PSC73753.1 - 0.0087 15.8 0.1 4.9 6.8 0.0 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.12 PSC73753.1 - 0.018 14.9 0.1 0.033 14.1 0.1 1.4 1 0 0 1 1 1 0 NACHT domain DnaB_C PF03796.15 PSC73753.1 - 0.019 14.3 0.1 0.061 12.6 0.0 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain TsaE PF02367.17 PSC73753.1 - 0.021 14.8 0.0 0.041 13.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 PSC73753.1 - 0.048 13.7 0.0 7.4 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 PSC73753.1 - 0.053 12.8 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_32 PF13654.6 PSC73753.1 - 0.057 12.2 0.0 5 5.8 0.0 2.4 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 PSC73753.1 - 0.057 13.4 0.0 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_18 PF13238.6 PSC73753.1 - 0.094 13.3 0.0 0.24 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain GvpD PF07088.11 PSC73753.1 - 0.1 11.2 0.0 0.44 9.1 0.0 1.8 2 0 0 2 2 2 0 GvpD gas vesicle protein Zeta_toxin PF06414.12 PSC73753.1 - 0.12 11.6 0.2 0.25 10.6 0.2 1.4 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 PSC73753.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Snf7 PF03357.21 PSC73754.1 - 2.8e-27 95.4 3.2 3.9e-27 95.0 3.2 1.1 1 0 0 1 1 1 1 Snf7 DUF3375 PF11855.8 PSC73754.1 - 0.00059 18.9 5.8 0.00073 18.6 5.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3375) PAS_10 PF13596.6 PSC73754.1 - 0.027 15.1 0.7 0.19 12.4 0.3 2.1 1 1 1 2 2 2 0 PAS domain ATP-synt_D PF01813.17 PSC73754.1 - 0.028 14.2 0.9 0.04 13.8 0.9 1.3 1 0 0 1 1 1 0 ATP synthase subunit D YlqD PF11068.8 PSC73754.1 - 0.093 13.1 4.8 0.096 13.1 1.5 2.1 1 1 1 2 2 2 0 YlqD protein Spc24 PF08286.11 PSC73754.1 - 0.16 12.2 1.0 1.6 9.0 0.4 2.4 2 1 1 3 3 3 0 Spc24 subunit of Ndc80 DUF647 PF04884.14 PSC73754.1 - 0.17 11.5 2.1 0.24 11.0 1.8 1.4 1 1 0 1 1 1 0 Vitamin B6 photo-protection and homoeostasis DUF4407 PF14362.6 PSC73754.1 - 0.43 9.9 9.2 0.72 9.2 9.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) APG6_N PF17675.1 PSC73754.1 - 2.3 8.7 5.0 0.83 10.2 0.2 2.3 2 1 0 2 2 2 0 Apg6 coiled-coil region RRM_1 PF00076.22 PSC73755.1 - 1.2e-27 95.5 0.1 2.1e-12 46.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PSC73755.1 - 6.3e-09 35.5 0.0 8.6e-05 22.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PSC73755.1 - 2.8e-07 30.3 0.0 0.0026 17.6 0.0 2.4 2 1 0 2 2 2 2 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 PSC73755.1 - 0.13 12.3 0.1 1.1 9.4 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif AAA_11 PF13086.6 PSC73756.1 - 0.0083 15.9 26.7 0.0083 15.9 26.7 2.2 2 0 0 2 2 2 1 AAA domain SID-1_RNA_chan PF13965.6 PSC73756.1 - 1.6 7.0 15.1 4.1 5.7 15.1 1.6 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Glyco_transf_41 PF13844.6 PSC73756.1 - 1.9 6.8 19.0 3.6 5.9 19.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 41 Exonuc_VII_L PF02601.15 PSC73756.1 - 2.8 7.4 43.5 0.17 11.4 32.8 2.4 2 0 0 2 2 2 0 Exonuclease VII, large subunit HABP4_PAI-RBP1 PF04774.15 PSC73759.1 - 4.2e-15 56.6 14.5 4.2e-15 56.6 14.5 2.4 2 1 0 2 2 2 1 Hyaluronan / mRNA binding family YscO-like PF16789.5 PSC73759.1 - 0.42 10.6 10.2 0.63 10.1 10.2 1.3 1 0 0 1 1 1 0 YscO-like protein Cullin_binding PF03556.15 PSC73760.1 - 1e-23 84.1 0.0 1.3e-23 83.7 0.0 1.1 1 0 0 1 1 1 1 Cullin binding SDA1 PF05285.12 PSC73761.1 - 0.88 8.9 8.4 0.055 12.9 3.5 1.4 2 0 0 2 2 2 0 SDA1 Mito_carr PF00153.27 PSC73762.1 - 3.3e-71 235.3 1.2 1.9e-23 82.2 0.0 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein 5-FTHF_cyc-lig PF01812.20 PSC73762.1 - 6.3e-33 114.2 0.0 8.8e-33 113.7 0.0 1.2 1 0 0 1 1 1 1 5-formyltetrahydrofolate cyclo-ligase family DUF1990 PF09348.10 PSC73763.1 - 3.7e-37 127.7 3.6 4.4e-36 124.3 3.6 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF1990) DUF2505 PF10698.9 PSC73764.1 - 0.00098 19.3 0.0 0.003 17.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2505) F5_F8_type_C PF00754.25 PSC73765.1 - 1.6e-06 28.2 1.7 4e-06 27.0 1.7 1.6 1 1 0 1 1 1 1 F5/8 type C domain CAP_N PF01213.19 PSC73765.1 - 2 7.8 7.7 0.41 10.1 4.0 1.7 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal PIF1 PF05970.14 PSC73766.1 - 3.7e-39 134.9 0.0 5.9e-24 84.9 0.0 2.9 2 1 0 2 2 2 2 PIF1-like helicase AAA_30 PF13604.6 PSC73766.1 - 7.8e-17 61.6 0.0 7.7e-16 58.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain zf-CCHC PF00098.23 PSC73766.1 - 8e-14 51.0 19.4 9.6e-07 28.6 0.8 4.1 3 1 0 3 3 3 3 Zinc knuckle AAA_19 PF13245.6 PSC73766.1 - 7.6e-09 36.1 0.0 2.3e-06 28.0 0.0 2.4 1 1 0 1 1 1 1 AAA domain zf-CCHC_2 PF13696.6 PSC73766.1 - 2.2e-07 30.5 16.8 0.0085 15.9 1.3 3.8 3 0 0 3 3 3 3 Zinc knuckle zf-CCHC_3 PF13917.6 PSC73766.1 - 1.3e-06 28.2 7.5 0.0058 16.6 0.0 3.7 3 0 0 3 3 3 2 Zinc knuckle AAA_16 PF13191.6 PSC73766.1 - 1.5e-06 28.7 0.2 3.8e-06 27.4 0.2 1.6 1 0 0 1 1 1 1 AAA ATPase domain zf-CCHC_5 PF14787.6 PSC73766.1 - 1.1e-05 25.0 20.4 0.035 13.8 2.4 4.0 3 0 0 3 3 3 3 GAG-polyprotein viral zinc-finger AAA_22 PF13401.6 PSC73766.1 - 4.1e-05 23.9 0.2 0.0009 19.5 0.2 2.3 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 PSC73766.1 - 0.00089 19.0 0.0 0.0018 18.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Viral_helicase1 PF01443.18 PSC73766.1 - 0.00096 19.0 0.0 0.042 13.6 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase DUF2075 PF09848.9 PSC73766.1 - 0.002 17.4 0.0 0.0046 16.2 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.12 PSC73766.1 - 0.0039 17.1 0.0 0.0078 16.1 0.0 1.5 1 0 0 1 1 1 1 NACHT domain PhoH PF02562.16 PSC73766.1 - 0.0047 16.4 0.0 0.0085 15.6 0.0 1.3 1 0 0 1 1 1 1 PhoH-like protein AAA_7 PF12775.7 PSC73766.1 - 0.005 16.4 0.0 0.0084 15.6 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region RsgA_GTPase PF03193.16 PSC73766.1 - 0.0079 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 RsgA GTPase AAA_11 PF13086.6 PSC73766.1 - 0.029 14.2 0.1 4.4 7.0 0.0 2.5 1 1 1 2 2 2 0 AAA domain T2SSE PF00437.20 PSC73766.1 - 0.04 13.0 0.0 0.067 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein eIF3g PF12353.8 PSC73766.1 - 0.055 13.9 10.7 1.3 9.4 0.2 3.5 3 0 0 3 3 3 0 Eukaryotic translation initiation factor 3 subunit G UvrD_C_2 PF13538.6 PSC73766.1 - 0.064 13.1 0.0 0.16 11.8 0.0 1.7 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain AAA_25 PF13481.6 PSC73766.1 - 0.068 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Herpes_Helicase PF02689.14 PSC73766.1 - 0.073 11.0 0.0 0.13 10.2 0.0 1.3 1 0 0 1 1 1 0 Helicase AAA_5 PF07728.14 PSC73766.1 - 0.076 13.0 0.0 0.18 11.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Bac_DnaA PF00308.18 PSC73766.1 - 0.087 12.7 0.0 0.14 12.0 0.0 1.2 1 0 0 1 1 1 0 Bacterial dnaA protein RNA_helicase PF00910.22 PSC73766.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 RNA helicase NDUFA12 PF05071.16 PSC73767.1 - 9.7e-17 61.6 8.0 1.8e-16 60.7 8.0 1.4 1 1 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 2-oxogl_dehyd_N PF16078.5 PSC73767.1 - 0.011 15.4 0.4 0.034 13.8 0.4 1.8 1 0 0 1 1 1 0 2-oxoglutarate dehydrogenase N-terminus Pkinase PF00069.25 PSC73768.1 - 1.3e-38 132.9 0.0 3.5e-38 131.5 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73768.1 - 3.1e-35 121.7 0.0 1.9e-34 119.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase PAN_4 PF14295.6 PSC73768.1 - 0.00024 20.9 10.5 0.0088 15.9 1.3 3.2 3 0 0 3 3 3 2 PAN domain PAN_1 PF00024.26 PSC73768.1 - 0.0086 16.0 0.5 0.044 13.7 0.1 2.2 2 0 0 2 2 2 1 PAN domain DNA_photolyase PF00875.18 PSC73769.1 - 8.3e-41 139.7 0.0 1.3e-40 139.0 0.0 1.3 1 0 0 1 1 1 1 DNA photolyase CIAPIN1 PF05093.13 PSC73770.1 - 1.5e-17 63.9 14.1 8.7e-15 55.1 2.6 2.3 1 1 1 2 2 2 2 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 PSC73770.1 - 0.024 14.9 0.0 0.047 13.9 0.0 1.5 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus Methyltransf_23 PF13489.6 PSC73770.1 - 0.065 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Spc7 PF08317.11 PSC73771.1 - 0.021 13.7 28.2 0.09 11.6 8.0 3.1 2 1 1 3 3 3 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 PSC73771.1 - 0.38 10.8 22.1 0.95 9.5 3.8 4.2 2 1 2 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF3829 PF12889.7 PSC73771.1 - 2.6 7.5 13.2 2 7.8 8.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3829) DUF812 PF05667.11 PSC73771.1 - 3.2 6.5 21.6 23 3.7 21.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF812) Hamartin PF04388.12 PSC73771.1 - 9 4.8 8.7 2.9 6.5 5.6 1.5 1 1 0 1 1 1 0 Hamartin protein LRR_1 PF00560.33 PSC73772.1 - 0.096 13.3 5.6 23 6.1 0.1 4.6 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 PSC73772.1 - 0.2 12.1 3.3 19 5.8 1.1 4.3 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PSC73772.1 - 0.71 10.1 1.8 14 6.0 0.3 3.1 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 PSC73773.1 - 0.096 13.3 5.6 23 6.1 0.1 4.6 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 PSC73773.1 - 0.2 12.1 3.3 19 5.8 1.1 4.3 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PSC73773.1 - 0.71 10.1 1.8 14 6.0 0.3 3.1 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 PSC73774.1 - 0.095 13.3 5.6 23 6.1 0.1 4.6 5 0 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 PSC73774.1 - 0.15 12.5 2.9 18 5.9 1.0 4.3 4 1 0 4 4 4 0 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PSC73774.1 - 0.71 10.1 1.8 14 6.0 0.3 3.1 3 0 0 3 3 3 0 Leucine Rich repeat FabA PF07977.13 PSC73775.1 - 5.3e-32 110.3 0.1 7.2e-32 109.9 0.1 1.2 1 0 0 1 1 1 1 FabA-like domain MaoC_dehydratas PF01575.19 PSC73775.1 - 0.012 15.1 0.1 0.022 14.3 0.1 1.4 1 0 0 1 1 1 0 MaoC like domain MaoC_dehydrat_N PF13452.6 PSC73775.1 - 0.15 12.2 0.0 0.63 10.2 0.0 1.9 1 1 1 2 2 2 0 N-terminal half of MaoC dehydratase Fe-S_biosyn PF01521.20 PSC73776.1 - 1.7e-15 57.2 0.0 2.1e-15 56.8 0.0 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Phage_Gp17 PF17549.2 PSC73776.1 - 0.15 12.1 0.0 0.2 11.7 0.0 1.1 1 0 0 1 1 1 0 Gene Product 17 EspB PF05802.11 PSC73777.1 - 0.19 11.7 2.9 0.9 9.5 1.5 1.9 1 1 0 1 1 1 0 Enterobacterial EspB protein Apolipoprotein PF01442.18 PSC73778.1 - 0.0048 16.8 6.8 0.057 13.3 1.2 3.7 2 2 1 3 3 3 2 Apolipoprotein A1/A4/E domain Herpes_capsid PF06112.11 PSC73778.1 - 1.5 8.9 6.7 5.2 7.1 6.7 1.9 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein VSP PF03302.13 PSC73778.1 - 1.5 7.6 77.4 0.043 12.7 17.6 4.4 1 1 2 4 4 4 0 Giardia variant-specific surface protein SRF-TF PF00319.18 PSC73779.1 - 1.3e-12 46.9 0.0 2e-12 46.4 0.0 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) RRM_1 PF00076.22 PSC73781.1 - 4.6e-28 96.8 0.0 1.5e-14 53.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apt1 PF10351.9 PSC73781.1 - 0.49 9.2 11.0 0.016 14.1 4.0 1.9 2 0 0 2 2 2 0 Golgi-body localisation protein domain CDP-OH_P_transf PF01066.21 PSC73784.1 - 0.015 16.0 0.3 0.021 15.6 0.3 1.3 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase MA3 PF02847.17 PSC73785.1 - 5.7e-26 90.7 0.4 1.2e-25 89.7 0.4 1.6 1 0 0 1 1 1 1 MA3 domain MIF4G PF02854.19 PSC73785.1 - 3.3e-16 59.6 0.1 1.9e-15 57.1 0.0 2.3 3 0 0 3 3 3 1 MIF4G domain Apt1 PF10351.9 PSC73785.1 - 0.032 13.1 17.5 0.043 12.7 10.2 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain TraG_N PF07916.11 PSC73785.1 - 0.06 12.2 0.1 0.099 11.5 0.1 1.3 1 0 0 1 1 1 0 TraG-like protein, N-terminal region SSP160 PF06933.11 PSC73785.1 - 0.28 9.3 20.6 0.39 8.9 20.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DNA_pol_phi PF04931.13 PSC73785.1 - 0.28 9.2 26.8 0.54 8.3 6.8 2.6 3 0 0 3 3 3 0 DNA polymerase phi SpoIIIAH PF12685.7 PSC73785.1 - 0.41 10.5 17.0 1 9.1 7.2 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein DUF913 PF06025.12 PSC73785.1 - 0.84 8.5 10.6 2.5 7.0 3.5 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) BSP_II PF05432.11 PSC73785.1 - 0.91 9.2 32.3 0.026 14.2 9.3 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) SAPS PF04499.15 PSC73785.1 - 1.1 8.0 8.4 1.7 7.3 0.4 2.3 2 0 0 2 2 2 0 SIT4 phosphatase-associated protein MID_MedPIWI PF18296.1 PSC73785.1 - 1.8 8.3 7.7 0.2 11.4 0.8 2.2 2 0 0 2 2 2 0 MID domain of medPIWI Zip PF02535.22 PSC73785.1 - 2.3 7.4 8.8 4.8 6.3 0.3 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter Proteasome PF00227.26 PSC73786.1 - 1.4e-43 148.6 0.3 1.6e-43 148.4 0.3 1.0 1 0 0 1 1 1 1 Proteasome subunit PDDEXK_6 PF04720.12 PSC73787.1 - 9e-22 78.1 0.0 1.3e-21 77.6 0.0 1.2 1 0 0 1 1 1 1 PDDEXK-like family of unknown function INCENP_ARK-bind PF03941.15 PSC73788.1 - 2e-16 59.7 0.2 2e-16 59.7 0.2 2.0 2 0 0 2 2 2 1 Inner centromere protein, ARK binding region Macoilin PF09726.9 PSC73788.1 - 0.13 10.9 43.8 0.0053 15.4 29.9 2.8 2 0 0 2 2 2 0 Macoilin family HEM4 PF02602.15 PSC73789.1 - 4.1e-41 140.9 0.7 4.1e-41 140.9 0.7 1.7 2 0 0 2 2 2 1 Uroporphyrinogen-III synthase HemD DUF810 PF05664.11 PSC73790.1 - 2.5e-66 224.7 0.0 1.1e-65 222.6 0.0 2.1 1 1 1 2 2 2 1 Plant family of unknown function (DUF810) MIIP PF15734.5 PSC73790.1 - 0.21 11.0 0.3 24 4.2 0.0 2.9 3 0 0 3 3 3 0 Migration and invasion-inhibitory Isochorismatase PF00857.20 PSC73791.1 - 5.8e-26 91.7 0.1 1.2e-25 90.6 0.1 1.6 1 0 0 1 1 1 1 Isochorismatase family rve PF00665.26 PSC73791.1 - 1.5e-20 73.5 0.0 4.3e-18 65.6 0.0 2.5 2 0 0 2 2 2 2 Integrase core domain Pkinase PF00069.25 PSC73791.1 - 2.8e-14 53.1 0.0 5.6e-14 52.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73791.1 - 2.6e-10 40.0 0.0 4.4e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-MYND PF01753.18 PSC73791.1 - 2.3e-06 27.6 10.9 8.1e-06 25.8 10.9 2.0 1 0 0 1 1 1 1 MYND finger rve_3 PF13683.6 PSC73791.1 - 0.014 15.1 0.0 0.039 13.7 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain DUF1840 PF08895.11 PSC73791.1 - 0.056 13.8 3.8 0.22 11.9 3.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF3783 PF12646.7 PSC73792.1 - 1.1e-12 47.7 0.0 1.7e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3783) Ribosomal_60s PF00428.19 PSC73792.1 - 3 8.5 8.3 12 6.6 5.9 2.4 2 1 0 2 2 2 0 60s Acidic ribosomal protein HA PF03457.14 PSC73793.1 - 5.8e-25 87.4 7.4 2.2e-12 47.1 0.8 3.4 3 0 0 3 3 3 2 Helicase associated domain SAD_SRA PF02182.17 PSC73794.1 - 2.5e-16 59.7 0.0 2.5e-16 59.7 0.0 2.4 2 0 0 2 2 1 1 SAD/SRA domain EamA PF00892.20 PSC73794.1 - 2.8e-13 50.2 32.4 5.5e-07 29.8 9.1 2.4 2 0 0 2 2 2 2 EamA-like transporter family TFIIA PF03153.13 PSC73794.1 - 0.017 15.2 32.9 0.029 14.4 32.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CCDC53 PF10152.9 PSC73794.1 - 0.1 13.0 10.5 0.23 11.8 10.5 1.5 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF4770 PF15994.5 PSC73794.1 - 0.11 12.8 10.6 0.21 11.8 10.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) DDHD PF02862.17 PSC73794.1 - 0.11 12.7 6.1 0.18 11.9 6.1 1.2 1 0 0 1 1 1 0 DDHD domain AAA_23 PF13476.6 PSC73794.1 - 0.12 12.9 8.0 0.17 12.4 8.0 1.2 1 0 0 1 1 1 0 AAA domain Neur_chan_memb PF02932.16 PSC73794.1 - 0.17 11.9 4.5 0.31 11.1 4.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Med15 PF09606.10 PSC73794.1 - 0.2 10.3 28.9 0.36 9.5 28.9 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal eIF-3_zeta PF05091.12 PSC73794.1 - 0.21 10.5 14.9 0.29 10.1 14.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PAT1 PF09770.9 PSC73794.1 - 0.25 9.6 22.0 0.37 9.0 22.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 SpoIIP PF07454.11 PSC73794.1 - 0.28 10.6 10.3 0.42 10.0 10.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) DUF2126 PF09899.9 PSC73794.1 - 0.29 9.2 5.4 0.42 8.6 5.4 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) MDM31_MDM32 PF08118.11 PSC73794.1 - 0.31 9.7 3.1 0.45 9.1 3.1 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins EOS1 PF12326.8 PSC73794.1 - 0.41 10.6 1.4 0.77 9.7 1.4 1.4 1 0 0 1 1 1 0 N-glycosylation protein SprA-related PF12118.8 PSC73794.1 - 0.49 9.5 24.0 0.85 8.7 24.0 1.3 1 0 0 1 1 1 0 SprA-related family Suf PF05843.14 PSC73794.1 - 0.51 10.3 15.4 0.78 9.7 15.4 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF778 PF05608.12 PSC73794.1 - 0.53 10.6 5.3 0.98 9.8 5.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF778) DUF2203 PF09969.9 PSC73794.1 - 0.54 11.0 6.3 1.2 9.8 6.3 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) RR_TM4-6 PF06459.12 PSC73794.1 - 0.69 9.7 8.7 1.1 9.0 8.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM60A PF15396.6 PSC73794.1 - 1.1 9.2 5.8 1.8 8.5 5.8 1.2 1 0 0 1 1 1 0 Protein Family FAM60A GvpL_GvpF PF06386.11 PSC73794.1 - 1.1 9.1 11.6 3 7.7 11.6 1.6 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF CPSF100_C PF13299.6 PSC73794.1 - 1.8 8.7 9.2 3.5 7.8 9.2 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal HNOBA PF07701.14 PSC73794.1 - 2 7.8 10.6 3.3 7.1 10.6 1.2 1 0 0 1 1 1 0 Heme NO binding associated EPL1 PF10513.9 PSC73794.1 - 2.5 8.4 11.8 4.8 7.6 11.8 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like CobT PF06213.12 PSC73794.1 - 2.7 7.3 19.2 5.6 6.3 19.2 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT V_ATPase_I PF01496.19 PSC73794.1 - 3.2 5.6 10.1 4.6 5.0 10.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EIIBC-GUT_N PF03612.14 PSC73794.1 - 3.3 7.4 12.0 5.6 6.7 12.0 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus GREB1 PF15782.5 PSC73794.1 - 3.5 4.6 9.1 4.6 4.2 9.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Connexin PF00029.19 PSC73794.1 - 3.8 7.2 7.3 6.4 6.5 7.3 1.2 1 0 0 1 1 1 0 Connexin BORG_CEP PF14957.6 PSC73794.1 - 4.4 8.5 8.9 9.9 7.4 8.9 1.5 1 0 0 1 1 1 0 Cdc42 effector ALMT PF11744.8 PSC73794.1 - 5.2 5.8 6.3 8.8 5.0 6.3 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter FAM176 PF14851.6 PSC73794.1 - 5.3 6.7 8.2 11 5.6 8.2 1.5 1 0 0 1 1 1 0 FAM176 family DUF3408 PF11888.8 PSC73794.1 - 5.5 7.1 15.0 10 6.3 15.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) SLC12 PF03522.15 PSC73794.1 - 5.6 5.9 10.2 9.8 5.1 10.2 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Pex14_N PF04695.13 PSC73794.1 - 5.6 7.6 26.7 0.59 10.8 21.8 1.8 2 0 0 2 2 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tim54 PF11711.8 PSC73794.1 - 8.1 5.1 11.4 12 4.5 11.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Baculo_PP31 PF05311.11 PSC73794.1 - 8.5 5.8 9.5 13 5.2 9.5 1.1 1 0 0 1 1 1 0 Baculovirus 33KDa late protein (PP31) HemX PF04375.14 PSC73794.1 - 9.8 5.3 29.7 5.6 6.2 27.4 1.6 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase SNF2_N PF00176.23 PSC73795.1 - 1.2e-59 201.9 0.0 2.3e-59 200.9 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-C3HC4_2 PF13923.6 PSC73795.1 - 8.6e-10 38.3 9.9 1.5e-09 37.5 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC73795.1 - 9.9e-09 35.4 10.4 1.9e-08 34.5 10.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PSC73795.1 - 6.1e-08 32.4 9.4 1e-07 31.7 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC73795.1 - 1.1e-06 28.4 7.1 1.9e-06 27.6 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC73795.1 - 7.8e-05 22.6 9.0 0.00014 21.7 9.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PSC73795.1 - 0.00014 21.8 5.9 0.00014 21.8 5.9 2.1 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PSC73795.1 - 0.00022 21.0 9.6 0.007 16.2 9.7 2.4 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PSC73795.1 - 0.0013 18.9 9.4 0.0029 17.7 9.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Spt20 PF12090.8 PSC73795.1 - 0.002 17.8 2.0 0.002 17.8 2.0 3.2 2 1 1 3 3 1 1 Spt20 family Helicase_C PF00271.31 PSC73795.1 - 0.007 16.7 0.0 0.013 15.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-rbx1 PF12678.7 PSC73795.1 - 0.045 14.0 5.9 0.13 12.6 5.9 1.8 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 PSC73795.1 - 0.046 13.5 5.6 0.1 12.4 5.6 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RCR PF12273.8 PSC73795.1 - 1.5 9.5 17.8 3.5 8.3 9.4 2.6 2 0 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red zf-RING_6 PF14835.6 PSC73795.1 - 1.6 8.7 4.1 7.5 6.5 4.5 1.8 2 0 0 2 2 2 0 zf-RING of BARD1-type protein PAT1 PF09770.9 PSC73795.1 - 2.5 6.3 26.2 3.5 5.8 17.9 2.1 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 zf-RING_11 PF17123.5 PSC73795.1 - 4 7.3 7.3 9.7 6.0 7.3 1.7 1 0 0 1 1 1 0 RING-like zinc finger SET PF00856.28 PSC73796.1 - 9e-14 52.2 0.0 5.6e-13 49.6 0.0 2.3 2 1 0 2 2 2 1 SET domain TPR_1 PF00515.28 PSC73796.1 - 1.1e-11 44.0 14.3 4.1e-07 29.5 0.1 4.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 PSC73796.1 - 1.9e-11 43.1 15.5 6.2e-07 29.0 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 PSC73796.1 - 6.8e-11 41.7 0.5 3.3e-09 36.3 0.0 2.9 1 1 1 2 2 2 1 TPR repeat TPR_9 PF13371.6 PSC73796.1 - 1.6e-10 40.9 6.9 1.5e-07 31.5 1.3 3.3 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.6 PSC73796.1 - 3.8e-08 33.2 6.4 5.8e-06 26.3 0.3 3.6 3 1 0 3 3 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PSC73796.1 - 3.4e-05 24.0 2.0 3.4e-05 24.0 2.0 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 PSC73796.1 - 5.3e-05 23.6 16.4 0.00023 21.6 0.1 3.7 2 1 2 4 4 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 PSC73796.1 - 0.0006 20.4 0.2 0.0006 20.4 0.2 6.1 6 2 1 7 7 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 PSC73796.1 - 0.0011 19.2 3.3 0.0011 19.2 3.3 3.4 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 PSC73796.1 - 0.0034 17.3 6.6 0.027 14.5 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 PSC73796.1 - 0.015 15.7 1.4 0.077 13.4 0.0 2.5 1 1 0 2 2 2 0 Alkyl sulfatase dimerisation TPR_8 PF13181.6 PSC73796.1 - 0.16 12.3 3.8 2.7 8.4 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PSC73796.1 - 0.26 11.4 3.0 9.8 6.3 0.0 3.3 3 1 1 4 4 4 0 Fis1 C-terminal tetratricopeptide repeat Sec1 PF00995.23 PSC73797.1 - 0.00013 21.4 0.0 0.025 13.8 0.0 2.1 2 0 0 2 2 2 2 Sec1 family Treacle PF03546.14 PSC73797.1 - 6 5.6 14.7 7.7 5.2 9.6 2.2 2 0 0 2 2 2 0 Treacher Collins syndrome protein Treacle F-box-like PF12937.7 PSC73798.1 - 1.5e-09 37.6 0.3 3.8e-09 36.3 0.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PSC73798.1 - 0.00017 21.4 0.1 0.00017 21.4 0.1 2.8 3 0 0 3 3 3 1 F-box domain Pkinase PF00069.25 PSC73799.1 - 1.5e-43 149.1 0.0 3e-18 66.1 0.0 3.0 3 0 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73799.1 - 2.2e-13 50.1 0.0 1.4e-05 24.5 0.0 2.9 2 1 1 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 PSC73799.1 - 0.03 13.6 0.0 0.78 9.0 0.0 2.4 3 0 0 3 3 3 0 Kinase-like FTA2 PF13095.6 PSC73799.1 - 0.087 12.4 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 p450 PF00067.22 PSC73800.1 - 8.5e-65 219.3 0.0 8e-45 153.4 0.0 2.2 2 0 0 2 2 2 2 Cytochrome P450 CRAL_TRIO PF00650.20 PSC73800.1 - 3.4e-23 82.1 0.0 5.7e-23 81.4 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PSC73800.1 - 0.085 13.0 0.0 0.16 12.1 0.0 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PSC73800.1 - 0.13 12.5 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 CRAL/TRIO, N-terminal domain MORN PF02493.20 PSC73801.1 - 0.0049 16.7 7.2 0.078 12.9 0.1 3.1 3 0 0 3 3 3 2 MORN repeat KCNQ2_u3 PF16642.5 PSC73801.1 - 0.18 12.8 7.5 0.16 13.0 6.0 1.7 1 1 0 1 1 1 0 Unstructured region on Potassium channel subunit alpha KvLQT2 Rox3 PF08633.10 PSC73801.1 - 5.2 7.3 7.7 14 5.9 7.7 1.9 1 1 0 1 1 1 0 Rox3 mediator complex subunit COG7 PF10191.9 PSC73802.1 - 1.2e-92 311.5 0.0 7.8e-60 203.0 0.0 2.8 2 1 0 2 2 2 2 Golgi complex component 7 (COG7) TPT PF03151.16 PSC73804.1 - 4.5e-14 52.5 11.7 5.7e-14 52.1 11.7 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 PSC73804.1 - 0.00063 19.0 8.4 0.00086 18.6 8.4 1.2 1 0 0 1 1 1 1 UAA transporter family Peptidase_U4 PF03419.13 PSC73805.1 - 0.34 10.2 8.0 0.6 9.3 7.9 1.5 1 1 0 1 1 1 0 Sporulation factor SpoIIGA DUF3318 PF11780.8 PSC73805.1 - 1.5 8.8 9.4 0.67 9.9 1.8 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3318) K_oxygenase PF13434.6 PSC73806.1 - 2.3e-13 50.0 0.0 7.6e-12 45.0 0.0 2.1 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.14 PSC73806.1 - 2.9e-11 43.2 0.0 1.4e-09 37.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PSC73806.1 - 6.2e-11 42.1 0.0 1e-10 41.4 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PSC73806.1 - 5.7e-08 32.9 1.8 5.9e-07 29.6 0.0 3.3 3 0 0 3 3 3 1 FAD-NAD(P)-binding Pyr_redox PF00070.27 PSC73806.1 - 0.06 13.9 0.6 1.6 9.3 0.0 2.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TSC22 PF01166.18 PSC73806.1 - 0.27 11.6 4.0 0.42 11.0 2.2 2.1 2 0 0 2 2 2 0 TSC-22/dip/bun family Leu_zip PF15294.6 PSC73806.1 - 2 7.9 9.4 1.5 8.3 8.0 1.4 1 1 0 1 1 1 0 Leucine zipper ALMS_motif PF15309.6 PSC73806.1 - 2 8.9 6.8 4.7 7.7 6.8 1.6 1 0 0 1 1 1 0 ALMS motif NAD_binding_8 PF13450.6 PSC73806.1 - 3.3 8.0 0.0 3.3 8.0 0.0 3.9 5 0 0 5 5 5 0 NAD(P)-binding Rossmann-like domain CorA PF01544.18 PSC73806.1 - 6.3 6.0 5.9 10 5.4 5.9 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein ALS_ss_C PF10369.9 PSC73807.1 - 4.1e-53 177.5 4.1 1.8e-25 88.9 0.1 3.3 4 0 0 4 4 4 2 Small subunit of acetolactate synthase ACT PF01842.25 PSC73807.1 - 1.4e-25 88.7 3.6 2.5e-14 52.7 0.0 3.0 2 1 0 2 2 2 2 ACT domain ACT_5 PF13710.6 PSC73807.1 - 2.2e-23 81.8 0.1 5.2e-13 48.6 0.0 2.9 3 0 0 3 3 3 2 ACT domain ACT_4 PF13291.6 PSC73807.1 - 3.4e-10 40.4 3.4 0.00089 19.8 0.3 3.2 3 1 0 3 3 3 2 ACT domain HTH_34 PF13601.6 PSC73807.1 - 0.00069 19.7 0.3 0.018 15.2 0.1 2.4 2 0 0 2 2 2 1 Winged helix DNA-binding domain ACT_6 PF13740.6 PSC73807.1 - 0.036 14.0 2.0 7.6 6.6 0.1 3.3 4 0 0 4 4 4 0 ACT domain NikR_C PF08753.11 PSC73807.1 - 0.05 13.8 0.0 0.27 11.4 0.0 2.2 2 0 0 2 2 2 0 NikR C terminal nickel binding domain Fea1 PF07692.11 PSC73808.1 - 8.1e-17 61.3 9.2 2.4e-11 43.3 3.2 2.3 2 0 0 2 2 2 2 Low iron-inducible periplasmic protein NAPRTase PF04095.16 PSC73808.1 - 0.078 12.6 0.1 0.12 11.9 0.1 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family Adeno_PV PF03910.13 PSC73808.1 - 0.12 11.0 2.6 0.19 10.4 2.6 1.3 1 0 0 1 1 1 0 Adenovirus minor core protein PV SNF2_N PF00176.23 PSC73809.1 - 3.7e-21 75.2 0.0 1e-20 73.8 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-CW PF07496.15 PSC73809.1 - 6.3e-14 51.7 9.1 1.2e-13 50.9 9.1 1.5 1 0 0 1 1 1 1 CW-type Zinc Finger Chromo PF00385.24 PSC73809.1 - 3.6e-11 42.8 0.0 0.0003 20.7 0.0 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PWWP PF00855.17 PSC73809.1 - 4.8e-08 33.3 1.0 2.5e-06 27.8 0.3 3.5 4 0 0 4 4 4 1 PWWP domain Helicase_C PF00271.31 PSC73809.1 - 1.3e-05 25.5 0.0 2.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain EAR PF07897.11 PSC73809.1 - 0.25 11.0 0.6 0.73 9.5 0.6 1.8 1 0 0 1 1 1 0 Ethylene-responsive binding factor-associated repression SNF2_N PF00176.23 PSC73810.1 - 3.7e-21 75.2 0.0 1e-20 73.8 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain zf-CW PF07496.15 PSC73810.1 - 6.3e-14 51.7 9.1 1.2e-13 50.9 9.1 1.5 1 0 0 1 1 1 1 CW-type Zinc Finger Chromo PF00385.24 PSC73810.1 - 3.6e-11 42.8 0.0 0.0003 20.7 0.0 2.6 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain PWWP PF00855.17 PSC73810.1 - 4.8e-08 33.3 1.0 2.5e-06 27.8 0.3 3.5 4 0 0 4 4 4 1 PWWP domain Helicase_C PF00271.31 PSC73810.1 - 1.3e-05 25.5 0.0 2.6e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain EAR PF07897.11 PSC73810.1 - 0.25 11.0 0.6 0.73 9.5 0.6 1.8 1 0 0 1 1 1 0 Ethylene-responsive binding factor-associated repression zf-RING_2 PF13639.6 PSC73811.1 - 4.6e-06 26.8 16.8 8.4e-06 26.0 16.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PSC73811.1 - 0.0017 18.2 14.7 0.0031 17.3 14.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PSC73811.1 - 0.023 15.0 11.2 0.044 14.1 11.2 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 PSC73811.1 - 0.14 12.1 15.1 0.24 11.2 15.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PSC73811.1 - 0.32 11.2 14.7 0.61 10.3 14.7 1.5 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 PSC73811.1 - 2.7 7.8 13.5 5.2 6.9 13.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4470 PF14737.6 PSC73812.1 - 8.5e-11 41.9 0.0 2.1e-10 40.6 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4470) zf-MYND PF01753.18 PSC73812.1 - 2.5e-08 33.9 6.7 7e-08 32.4 6.7 1.8 1 0 0 1 1 1 1 MYND finger MULE PF10551.9 PSC73813.1 - 1.4e-15 57.5 0.0 9.6e-15 54.8 0.0 2.4 2 0 0 2 2 2 1 MULE transposase domain SWIM PF04434.17 PSC73813.1 - 4.2e-06 26.3 0.4 1.1e-05 25.0 0.4 1.7 1 0 0 1 1 1 1 SWIM zinc finger PurA PF04845.13 PSC73813.1 - 0.18 11.1 0.1 0.34 10.2 0.1 1.3 1 0 0 1 1 1 0 PurA ssDNA and RNA-binding protein AAA_12 PF13087.6 PSC73814.1 - 2.6e-55 187.2 0.0 6.5e-55 185.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PSC73814.1 - 7.8e-49 166.8 0.0 7.8e-49 166.8 0.0 3.5 3 1 0 3 3 3 1 AAA domain AAA_19 PF13245.6 PSC73814.1 - 3e-06 27.6 4.6 1.4e-05 25.5 1.3 3.2 2 1 0 2 2 2 1 AAA domain SEN1_N PF12726.7 PSC73814.1 - 0.00025 19.4 0.0 0.00045 18.6 0.0 1.4 1 0 0 1 1 1 1 SEN1 N terminal UvrD_C_2 PF13538.6 PSC73814.1 - 0.0018 18.1 0.2 0.0045 16.8 0.2 1.7 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Viral_helicase1 PF01443.18 PSC73814.1 - 0.0037 17.0 0.2 8.6 6.0 0.0 3.4 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.6 PSC73814.1 - 1.1 9.5 4.5 2.3 8.5 0.0 3.9 4 1 0 4 4 4 0 AAA domain EPL1 PF10513.9 PSC73814.1 - 1.4 9.3 7.1 0.31 11.4 2.6 2.2 2 0 0 2 2 2 0 Enhancer of polycomb-like rve PF00665.26 PSC73817.1 - 1.2e-18 67.4 0.0 4.5e-18 65.6 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain zf-C3HC4_3 PF13920.6 PSC73817.1 - 2.4e-10 40.1 8.8 4.5e-10 39.2 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC73817.1 - 0.00017 21.4 6.5 0.00034 20.4 6.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PSC73817.1 - 0.0003 20.6 11.5 0.0007 19.4 11.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PSC73817.1 - 0.0054 17.0 11.1 0.014 15.7 11.1 1.8 1 0 0 1 1 1 1 Ring finger domain rve_3 PF13683.6 PSC73817.1 - 0.017 14.9 0.0 0.041 13.6 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain zf-P11 PF03854.14 PSC73817.1 - 0.13 12.0 7.0 0.31 10.7 7.0 1.6 1 0 0 1 1 1 0 P-11 zinc finger EF-hand_6 PF13405.6 PSC73818.1 - 5.3e-06 25.9 0.0 1.2e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain EF-hand_1 PF00036.32 PSC73818.1 - 5.8e-06 25.5 0.0 2.6e-05 23.5 0.0 2.0 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 PSC73818.1 - 0.0002 21.7 0.0 0.00038 20.9 0.0 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 PSC73818.1 - 0.0015 17.9 0.0 0.004 16.6 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_8 PF13833.6 PSC73818.1 - 0.17 11.8 0.0 0.38 10.6 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair SelK_SelG PF10961.8 PSC73818.1 - 1 10.0 5.2 25 5.6 1.5 2.6 2 0 0 2 2 2 0 Selenoprotein SelK_SelG TPR_1 PF00515.28 PSC73819.1 - 4.1e-09 35.9 8.7 0.0023 17.7 2.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat Beta_helix PF13229.6 PSC73819.1 - 6.4e-09 35.9 0.0 1.2e-08 35.0 0.0 1.3 1 0 0 1 1 1 1 Right handed beta helix region TPR_2 PF07719.17 PSC73819.1 - 9e-09 34.8 14.4 0.013 15.6 3.8 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 PSC73819.1 - 0.00013 21.9 1.8 2.8 8.4 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PSC73819.1 - 0.00017 22.2 14.0 0.0092 16.7 0.6 3.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 PSC73819.1 - 0.00031 20.5 7.5 0.15 12.2 0.2 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 PSC73819.1 - 0.0038 17.5 15.8 0.03 14.6 0.9 3.2 3 1 0 3 3 3 2 Tetratricopeptide repeat NosD PF05048.13 PSC73819.1 - 0.0075 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Periplasmic copper-binding protein (NosD) TPR_10 PF13374.6 PSC73819.1 - 0.11 12.4 13.1 0.61 10.0 0.5 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 PSC73819.1 - 0.21 11.3 2.8 5 6.9 0.1 2.8 3 0 0 3 3 3 0 TPR repeat TPR_19 PF14559.6 PSC73819.1 - 0.4 11.2 7.3 2.3 8.8 1.9 2.8 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 PSC73819.1 - 0.45 11.2 19.0 1.2 9.9 4.7 3.3 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 PSC73819.1 - 0.75 10.3 5.3 4.3 7.9 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat BTAD PF03704.17 PSC73819.1 - 1.1 9.7 9.5 4.3 7.8 9.5 2.0 1 1 0 1 1 1 0 Bacterial transcriptional activator domain RL10P_insert PF17777.1 PSC73820.1 - 3.3e-20 71.8 0.0 5.3e-20 71.2 0.0 1.3 1 0 0 1 1 1 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 PSC73820.1 - 1.8e-16 60.1 0.0 2.7e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L10 GlcNAc_2-epim PF07221.11 PSC73821.1 - 9.2e-07 28.4 1.7 1.3e-06 27.9 1.7 1.1 1 0 0 1 1 1 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) TspO_MBR PF03073.15 PSC73822.1 - 2.7e-37 127.8 11.1 5.9e-37 126.7 11.1 1.5 1 0 0 1 1 1 1 TspO/MBR family Fip1 PF05182.13 PSC73822.1 - 2.8e-16 58.7 0.0 4.6e-16 58.0 0.0 1.3 1 0 0 1 1 1 1 Fip1 motif DUF1421 PF07223.11 PSC73822.1 - 0.013 15.3 1.4 0.29 11.0 0.0 3.0 2 1 1 3 3 3 0 UBA-like domain (DUF1421) Unstab_antitox PF09720.10 PSC73823.1 - 9.7 6.3 9.3 3.2 7.9 1.8 3.3 4 0 0 4 4 4 0 Putative addiction module component LTXXQ PF07813.12 PSC73824.1 - 0.019 15.7 0.2 0.019 15.7 0.2 3.3 4 0 0 4 4 4 0 LTXXQ motif family protein REGB_T4 PF10715.9 PSC73824.1 - 0.053 13.7 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 T4-page Endoribonuclease RegB DUF2423 PF10338.9 PSC73826.1 - 2.9e-07 30.6 1.4 2.9e-07 30.6 1.4 3.1 3 0 0 3 3 3 1 Protein of unknown function (DUF2423) MitMem_reg PF13012.6 PSC73827.1 - 8.2e-23 81.0 0.1 1.2e-22 80.4 0.1 1.2 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 PSC73827.1 - 1.7e-22 79.6 0.0 2.8e-22 78.9 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease RMI1_N PF08585.12 PSC73828.1 - 1.1e-37 129.9 0.0 3.2e-24 85.9 0.0 3.0 2 1 1 3 3 3 2 RecQ mediated genome instability protein RMI1_C PF16099.5 PSC73828.1 - 5.2e-09 36.1 0.0 8.5e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 Recq-mediated genome instability protein 1, C-terminal OB-fold Nop PF01798.18 PSC73830.1 - 4.2e-73 245.6 0.0 6.4e-73 245.0 0.0 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 PSC73830.1 - 1.2e-39 135.9 2.6 2.7e-39 134.8 2.6 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain CorA PF01544.18 PSC73830.1 - 1.5e-05 24.4 1.9 0.00022 20.7 0.0 2.9 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein TLE_N PF03920.15 PSC73830.1 - 0.018 15.1 0.1 0.053 13.6 0.1 1.7 1 0 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain DUF812 PF05667.11 PSC73830.1 - 0.14 11.0 0.4 0.24 10.2 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF812) HalX PF08663.10 PSC73830.1 - 5.7 7.3 8.1 2.3 8.6 1.7 3.5 2 1 1 3 3 3 0 HalX domain WW PF00397.26 PSC73831.1 - 3.4e-09 36.6 0.3 3.4e-09 36.6 0.3 2.1 3 0 0 3 3 3 1 WW domain zf-CCHC PF00098.23 PSC73831.1 - 6.3e-05 22.9 1.9 0.00011 22.2 1.9 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 PSC73831.1 - 0.014 15.1 0.8 0.025 14.3 0.8 1.3 1 0 0 1 1 1 0 Zinc knuckle AfaD PF05775.12 PSC73831.1 - 0.06 13.8 0.0 0.091 13.2 0.0 1.4 1 0 0 1 1 1 0 Enterobacteria AfaD invasin protein MTS PF05175.14 PSC73832.1 - 0.064 12.8 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Mpp10 PF04006.12 PSC73832.1 - 3.9 5.8 6.3 5.3 5.4 6.3 1.0 1 0 0 1 1 1 0 Mpp10 protein FA_hydroxylase PF04116.13 PSC73833.1 - 6e-10 39.6 14.9 4.7e-08 33.5 13.1 2.5 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily FA_hydroxylase PF04116.13 PSC73834.1 - 1.7e-12 47.8 12.0 1.7e-12 47.8 12.0 1.5 1 1 1 2 2 2 1 Fatty acid hydroxylase superfamily MFS_1 PF07690.16 PSC73835.1 - 3.2e-31 108.5 61.5 5.3e-24 84.8 17.7 3.5 3 0 0 3 3 3 2 Major Facilitator Superfamily MFS_1 PF07690.16 PSC73836.1 - 3.2e-31 108.5 61.5 5.3e-24 84.8 17.7 3.5 3 0 0 3 3 3 2 Major Facilitator Superfamily DUF4750 PF15938.5 PSC73838.1 - 0.0015 18.1 0.1 0.002 17.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4750) DEAD PF00270.29 PSC73839.1 - 9.6e-40 136.2 0.0 2.1e-39 135.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC73839.1 - 1.2e-30 106.1 0.0 3.8e-29 101.3 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC73839.1 - 4.7e-07 30.0 0.0 7.8e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 PSC73839.1 - 0.013 14.9 0.2 0.043 13.2 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.6 PSC73839.1 - 0.021 15.1 0.0 0.21 11.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 PSC73839.1 - 0.062 13.6 0.1 0.3 11.4 0.1 2.2 1 1 0 1 1 1 0 AAA domain tRNA-synt_1b PF00579.25 PSC73839.1 - 0.09 12.1 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) FUSC-like PF12805.7 PSC73839.1 - 0.1 11.6 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS Flavi_DEAD PF07652.14 PSC73839.1 - 0.18 11.7 0.0 0.45 10.5 0.0 1.7 1 1 0 1 1 1 0 Flavivirus DEAD domain UBA PF00627.31 PSC73840.1 - 0.034 14.0 2.7 0.062 13.2 0.1 2.8 3 0 0 3 3 3 0 UBA/TS-N domain OFCC1 PF15680.5 PSC73840.1 - 0.32 11.6 4.0 0.78 10.3 4.0 1.6 1 0 0 1 1 1 0 Orofacial cleft 1 candidate gene 1 protein zf-RING_2 PF13639.6 PSC73840.1 - 4.2 7.8 6.8 2.2 8.7 0.2 2.9 3 0 0 3 3 3 0 Ring finger domain BCDHK_Adom3 PF10436.9 PSC73841.1 - 1.8e-41 141.7 0.1 2.7e-41 141.1 0.1 1.3 1 0 0 1 1 1 1 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase NuA4 PF09340.10 PSC73841.1 - 2.6e-16 59.2 0.1 4.7e-16 58.4 0.1 1.4 1 0 0 1 1 1 1 Histone acetyltransferase subunit NuA4 HATPase_c PF02518.26 PSC73841.1 - 1.5e-07 31.9 0.0 7.5e-05 23.2 0.0 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PSC73841.1 - 0.043 13.6 0.0 0.08 12.8 0.0 1.3 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase XhlA PF10779.9 PSC73841.1 - 0.11 12.7 0.0 0.26 11.5 0.0 1.5 1 0 0 1 1 1 0 Haemolysin XhlA DUF3450 PF11932.8 PSC73841.1 - 0.26 10.5 2.3 0.53 9.5 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) MRP-S28 PF10213.9 PSC73842.1 - 3.9e-13 49.9 1.3 7.8e-13 49.0 0.3 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein DUF4106 PF13388.6 PSC73842.1 - 0.00095 18.5 12.4 0.0015 17.9 12.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4106) RF-1 PF00472.20 PSC73842.1 - 0.0082 16.1 4.6 0.013 15.4 4.6 1.3 1 0 0 1 1 1 1 RF-1 domain TFIIA PF03153.13 PSC73842.1 - 0.015 15.3 13.0 0.019 15.0 13.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF1266 PF06889.11 PSC73842.1 - 0.031 14.3 6.8 0.031 14.3 6.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1266) DUF5327 PF17261.2 PSC73842.1 - 0.084 13.6 12.5 0.24 12.2 12.5 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5327) TERB2 PF15101.6 PSC73842.1 - 0.18 11.9 5.1 0.29 11.2 5.1 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Suf PF05843.14 PSC73842.1 - 0.84 9.6 6.7 1.2 9.1 6.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF547 PF04784.14 PSC73843.1 - 1.4e-34 118.7 0.0 3.4e-34 117.5 0.0 1.6 2 0 0 2 2 2 1 Protein of unknown function, DUF547 DUF4079 PF13301.6 PSC73843.1 - 1.4e-22 80.4 3.0 2.8e-22 79.4 3.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4079) Glutaredoxin PF00462.24 PSC73843.1 - 2.1e-14 53.5 0.0 4.3e-14 52.5 0.0 1.6 1 0 0 1 1 1 1 Glutaredoxin DUF4405 PF14358.6 PSC73843.1 - 0.039 14.5 4.6 1.8 9.2 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4405) Cytochrom_B561 PF03188.16 PSC73843.1 - 0.1 12.7 2.5 0.21 11.7 2.5 1.4 1 0 0 1 1 1 0 Eukaryotic cytochrome b561 Ni_hydr_CYTB PF01292.20 PSC73843.1 - 4.6 6.8 7.0 53 3.3 7.0 2.3 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 ArfGap PF01412.18 PSC73844.1 - 1.3e-34 118.8 0.0 2.9e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BAR_3_WASP_bdg PF10456.9 PSC73845.1 - 0.064 12.7 0.0 0.08 12.4 0.0 1.3 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein MSP1_C PF07462.11 PSC73845.1 - 7.5 5.1 6.3 9.5 4.8 6.3 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus ABC_tran PF00005.27 PSC73846.1 - 1.3e-25 90.5 0.0 2.1e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PSC73846.1 - 2e-16 60.1 21.0 2e-16 60.1 21.0 2.2 2 1 0 2 2 2 1 ABC-2 family transporter protein HAD_2 PF13419.6 PSC73846.1 - 9.2e-16 58.4 0.0 3.8e-14 53.2 0.0 2.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PSC73846.1 - 4.4e-12 46.7 0.0 5.3e-09 36.7 0.0 3.2 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PSC73846.1 - 8.8e-10 38.5 0.0 1.9e-09 37.5 0.0 1.6 1 0 0 1 1 1 1 HAD-hyrolase-like AAA_21 PF13304.6 PSC73846.1 - 1.7e-09 37.9 0.0 2.2e-05 24.4 0.0 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system Methyltransf_11 PF08241.12 PSC73846.1 - 0.0006 20.4 0.4 2 9.1 0.1 2.8 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_31 PF13847.6 PSC73846.1 - 0.0033 17.2 0.0 0.16 11.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain HAD PF12710.7 PSC73846.1 - 0.0069 16.8 0.1 0.08 13.3 0.1 2.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Methyltransf_25 PF13649.6 PSC73846.1 - 0.019 15.7 0.5 2.1 9.1 0.1 3.4 3 0 0 3 3 3 0 Methyltransferase domain SMC_N PF02463.19 PSC73846.1 - 0.033 13.6 0.0 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 PSC73846.1 - 0.12 12.1 0.0 7.7 6.1 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 PSC73846.1 - 0.13 12.0 0.1 0.36 10.6 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Methyltransf_23 PF13489.6 PSC73846.1 - 0.14 12.0 0.0 7.1 6.4 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Zeta_toxin PF06414.12 PSC73846.1 - 0.16 11.3 0.0 0.27 10.5 0.0 1.2 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.6 PSC73846.1 - 0.21 12.1 0.3 0.38 11.2 0.3 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 PSC73846.1 - 0.32 10.2 7.8 0.85 8.8 7.8 1.7 1 0 0 1 1 1 0 ABC-2 family transporter protein DnaJ-X PF14308.6 PSC73847.1 - 2.7e-37 128.3 1.7 3.9e-37 127.8 1.7 1.2 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 PSC73847.1 - 4.9e-24 84.2 0.3 9.8e-24 83.3 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain TENA_THI-4 PF03070.16 PSC73847.1 - 1.3e-21 77.4 0.6 1.3e-21 77.4 0.6 1.6 2 0 0 2 2 2 1 TENA/THI-4/PQQC family DUF1192 PF06698.11 PSC73847.1 - 0.058 13.5 0.0 0.42 10.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) DnaJ-X PF14308.6 PSC73848.1 - 2.7e-37 128.3 1.7 3.9e-37 127.8 1.7 1.2 1 0 0 1 1 1 1 X-domain of DnaJ-containing DnaJ PF00226.31 PSC73848.1 - 4.9e-24 84.2 0.3 9.8e-24 83.3 0.3 1.6 1 0 0 1 1 1 1 DnaJ domain TENA_THI-4 PF03070.16 PSC73848.1 - 1.3e-21 77.4 0.6 1.3e-21 77.4 0.6 1.6 2 0 0 2 2 2 1 TENA/THI-4/PQQC family DUF1192 PF06698.11 PSC73848.1 - 0.058 13.5 0.0 0.42 10.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Metallophos PF00149.28 PSC73849.1 - 6.3e-15 56.2 0.0 9.4e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 PSC73849.1 - 2.9e-14 53.7 0.5 7.5e-08 33.1 0.0 3.8 3 0 0 3 3 3 2 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 PSC73849.1 - 1.3e-13 51.4 0.0 4.6e-13 49.6 0.0 2.0 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 PSC73849.1 - 0.0037 17.5 0.0 0.4 10.9 0.0 3.0 3 0 0 3 3 3 1 Calcineurin-like phosphoesterase superfamily domain Ysc84 PF04366.12 PSC73850.1 - 8e-06 25.6 0.0 1.7e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Las17-binding protein actin regulator Ysc84 PF04366.12 PSC73851.1 - 1.2e-05 25.0 0.0 2.4e-05 24.1 0.0 1.7 1 1 0 1 1 1 1 Las17-binding protein actin regulator zf-C3HC4_3 PF13920.6 PSC73852.1 - 2.7e-11 43.1 18.6 2.7e-11 43.1 18.6 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PSC73852.1 - 2.6e-05 24.0 15.9 2.6e-05 24.0 15.9 3.5 3 1 1 4 4 4 1 Prokaryotic RING finger family 4 EGF_2 PF07974.13 PSC73852.1 - 6.3e-05 23.3 10.6 6.3e-05 23.3 10.6 3.5 4 0 0 4 4 4 1 EGF-like domain HIT PF01230.23 PSC73853.1 - 7.7e-10 39.4 0.0 1.1e-09 38.9 0.0 1.2 1 0 0 1 1 1 1 HIT domain Metal_resist PF13801.6 PSC73853.1 - 0.051 13.8 2.7 0.73 10.0 0.0 2.7 3 0 0 3 3 3 0 Heavy-metal resistance TAF4 PF05236.14 PSC73854.1 - 1.1e-16 61.4 24.4 1.1e-16 61.4 24.4 4.4 1 1 0 2 2 2 1 Transcription initiation factor TFIID component TAF4 family Galactosyl_T PF01762.21 PSC73855.1 - 1.1e-25 90.6 0.0 5.7e-23 81.8 0.0 2.2 1 1 0 1 1 1 1 Galactosyltransferase ABC_tran_Xtn PF12848.7 PSC73855.1 - 0.13 12.3 3.8 0.37 10.8 3.8 1.8 1 0 0 1 1 1 0 ABC transporter TMF_TATA_bd PF12325.8 PSC73855.1 - 1.2 9.4 12.9 2 8.7 2.5 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 PSC73855.1 - 4.2 6.1 9.1 7.6 5.3 9.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Galactosyl_T PF01762.21 PSC73856.1 - 1.1e-25 90.6 0.0 5.7e-23 81.8 0.0 2.2 1 1 0 1 1 1 1 Galactosyltransferase ABC_tran_Xtn PF12848.7 PSC73856.1 - 0.13 12.3 3.8 0.37 10.8 3.8 1.8 1 0 0 1 1 1 0 ABC transporter TMF_TATA_bd PF12325.8 PSC73856.1 - 1.2 9.4 12.9 2 8.7 2.5 2.5 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spc7 PF08317.11 PSC73856.1 - 4.2 6.1 9.1 7.6 5.3 9.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein Ribosomal_TL5_C PF14693.6 PSC73857.1 - 1.1e-15 57.7 0.0 1.6e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein TL5, C-terminal domain Ribosomal_L25p PF01386.19 PSC73857.1 - 3.1e-09 37.2 0.0 5.1e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal L25p family AP2 PF00847.20 PSC73860.1 - 7.4e-14 51.7 1.9 1.9e-13 50.4 1.9 1.8 1 0 0 1 1 1 1 AP2 domain CotH PF08757.11 PSC73861.1 - 2.2e-30 106.3 0.0 1e-29 104.1 0.0 1.8 1 1 0 1 1 1 1 CotH kinase protein LTD PF00932.19 PSC73861.1 - 1.3e-19 70.6 0.0 5.4e-13 49.3 0.0 2.6 2 0 0 2 2 2 2 Lamin Tail Domain UvrD-helicase PF00580.21 PSC73862.1 - 1.3e-37 130.0 0.0 3e-37 128.8 0.0 1.6 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 PSC73862.1 - 8e-27 94.5 0.0 7.3e-17 61.8 0.0 2.2 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 PSC73862.1 - 1.2e-23 84.0 0.0 7.4e-23 81.5 0.0 2.2 1 1 0 1 1 1 1 AAA domain UvrD_C_2 PF13538.6 PSC73862.1 - 7.3e-09 35.3 0.3 0.00088 19.1 0.6 2.7 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_30 PF13604.6 PSC73862.1 - 3.4e-08 33.4 2.6 2.5e-05 24.1 0.7 3.0 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 PSC73862.1 - 0.00051 19.8 0.5 3 7.5 0.0 3.9 4 0 0 4 4 4 2 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 PSC73862.1 - 0.013 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 PSC73862.1 - 0.13 12.6 0.1 0.96 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_12 PF13087.6 PSC73862.1 - 0.16 11.6 0.0 1.4 8.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 PSC73862.1 - 0.69 9.5 12.8 0.046 13.3 2.9 3.1 3 0 0 3 3 3 0 AAA domain Kelch_1 PF01344.25 PSC73864.1 - 1.1e-70 233.0 7.5 6e-11 41.8 0.0 10.6 10 0 0 10 10 10 10 Kelch motif Kelch_6 PF13964.6 PSC73864.1 - 8.6e-55 181.4 7.1 8e-06 26.0 0.1 10.6 4 4 6 10 10 10 10 Kelch motif Kelch_2 PF07646.15 PSC73864.1 - 9.7e-21 72.9 9.5 0.13 12.3 0.0 10.3 10 0 0 10 10 10 6 Kelch motif Kelch_4 PF13418.6 PSC73864.1 - 1.8e-16 59.8 8.8 0.0091 16.0 0.0 10.3 10 0 0 10 10 10 4 Galactose oxidase, central domain Kelch_3 PF13415.6 PSC73864.1 - 9.5e-06 25.8 23.6 0.002 18.3 0.1 9.7 10 0 0 10 10 10 1 Galactose oxidase, central domain Kelch_5 PF13854.6 PSC73864.1 - 0.0003 20.7 24.9 0.096 12.7 0.1 7.8 9 0 0 9 9 9 2 Kelch motif Lectin_N PF03954.14 PSC73864.1 - 0.015 15.0 2.5 5.5 6.8 0.0 2.9 2 2 2 4 4 4 0 Hepatic lectin, N-terminal domain MbeD_MobD PF04899.12 PSC73864.1 - 0.1 12.7 6.5 4.9 7.3 0.7 2.9 2 0 0 2 2 2 0 MbeD/MobD like HAUS-augmin3 PF14932.6 PSC73864.1 - 0.1 12.2 0.9 13 5.2 0.1 2.2 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 Fer2_BFD PF04324.15 PSC73864.1 - 0.15 12.4 0.0 39 4.7 0.0 2.5 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain Peptidase_M76 PF09768.9 PSC73865.1 - 1.1e-44 152.2 5.4 6.3e-42 143.2 3.0 2.1 1 1 1 2 2 2 2 Peptidase M76 family MORN PF02493.20 PSC73865.1 - 2.9e-07 30.0 9.2 0.0012 18.6 0.8 3.1 2 1 0 2 2 2 2 MORN repeat Peptidase_M91 PF14891.6 PSC73865.1 - 0.016 15.5 0.0 0.024 15.0 0.0 1.2 1 0 0 1 1 1 0 Effector protein Mem_trans PF03547.18 PSC73865.1 - 0.034 12.6 0.8 4.7 5.5 1.5 2.1 2 0 0 2 2 2 0 Membrane transport protein LRV PF01816.17 PSC73865.1 - 0.05 14.0 0.9 0.34 11.4 0.9 2.6 1 0 0 1 1 1 0 Leucine rich repeat variant Usp PF00582.26 PSC73866.1 - 1e-19 71.5 22.5 1.6e-13 51.4 0.9 4.9 4 1 0 4 4 4 2 Universal stress protein family DNA_ligase_A_N PF04675.14 PSC73866.1 - 1.5e-13 51.4 0.0 3.1e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_M PF01068.21 PSC73866.1 - 7.8e-11 42.0 0.0 4.5e-06 26.4 0.0 2.9 3 0 0 3 3 3 2 ATP dependent DNA ligase domain PTCB-BRCT PF12738.7 PSC73866.1 - 0.035 14.1 0.1 0.31 11.0 0.0 2.5 3 0 0 3 3 3 0 twin BRCT domain LRR_4 PF12799.7 PSC73866.1 - 0.15 12.5 0.1 6.7 7.3 0.0 3.3 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) CDK2AP PF09806.9 PSC73866.1 - 4.5 7.3 11.3 0.097 12.7 2.6 2.3 2 0 0 2 2 2 0 Cyclin-dependent kinase 2-associated protein DER1 PF04511.15 PSC73867.1 - 6e-57 192.7 8.1 8.8e-57 192.1 8.1 1.2 1 0 0 1 1 1 1 Der1-like family HMGL-like PF00682.19 PSC73867.1 - 1.4e-54 185.4 0.1 2.9e-54 184.4 0.1 1.5 1 0 0 1 1 1 1 HMGL-like PFK PF00365.20 PSC73867.1 - 5.8e-44 150.5 0.3 9.2e-43 146.6 0.3 2.1 1 1 0 1 1 1 1 Phosphofructokinase MoCF_biosynth PF00994.24 PSC73867.1 - 0.032 13.9 0.4 0.4 10.3 0.0 2.7 2 1 0 2 2 2 0 Probable molybdopterin binding domain DER1 PF04511.15 PSC73868.1 - 6.1e-57 192.6 8.1 8.9e-57 192.1 8.1 1.2 1 0 0 1 1 1 1 Der1-like family HMGL-like PF00682.19 PSC73868.1 - 1.5e-54 185.4 0.1 2.9e-54 184.4 0.1 1.5 1 0 0 1 1 1 1 HMGL-like PFK PF00365.20 PSC73868.1 - 1.1e-46 159.4 0.2 1.8e-45 155.5 0.2 2.1 1 1 0 1 1 1 1 Phosphofructokinase MoCF_biosynth PF00994.24 PSC73868.1 - 0.029 14.0 0.5 0.34 10.6 0.0 2.7 2 1 0 2 2 2 0 Probable molybdopterin binding domain Ribosomal_L4 PF00573.22 PSC73869.1 - 8e-51 172.5 0.1 1e-50 172.1 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family CAP PF00188.26 PSC73870.1 - 1.7e-20 74.1 3.5 1.7e-20 74.1 3.5 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family DUF4478 PF14793.6 PSC73871.1 - 0.07 13.0 0.7 0.07 13.0 0.7 1.8 2 0 0 2 2 2 0 Pyrimidine/purine nucleotide 5'-monophosphate nucleosidases TFIIA PF03153.13 PSC73871.1 - 5.1 7.0 24.6 6.7 6.6 24.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HSCB_C PF07743.13 PSC73872.1 - 1.6e-15 57.3 0.4 1.6e-15 57.3 0.4 2.7 3 0 0 3 3 3 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 PSC73872.1 - 2.7e-05 24.2 0.6 2.7e-05 24.2 0.6 1.9 2 0 0 2 2 2 1 DnaJ domain HscB_4_cys PF18256.1 PSC73872.1 - 0.00061 19.6 3.5 0.0022 17.8 3.5 2.0 1 0 0 1 1 1 1 Co-chaperone HscB tetracysteine metal binding motif zf-ribbon_3 PF13248.6 PSC73872.1 - 0.0075 15.6 0.3 0.016 14.6 0.3 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 PSC73872.1 - 0.009 16.0 2.6 0.017 15.1 2.6 1.4 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 PSC73872.1 - 0.024 15.4 1.3 0.042 14.6 1.3 1.4 1 0 0 1 1 1 0 zinc-ribbon family HypA PF01155.19 PSC73872.1 - 0.035 14.1 0.2 0.078 13.0 0.2 1.6 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RskA PF10099.9 PSC73872.1 - 0.11 12.7 10.6 0.2 11.9 10.6 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA PLATZ PF04640.14 PSC73872.1 - 0.13 12.9 1.0 0.27 11.9 1.0 1.5 1 0 0 1 1 1 0 PLATZ transcription factor zinc_ribbon_2 PF13240.6 PSC73872.1 - 0.21 11.3 0.6 0.35 10.6 0.6 1.4 1 0 0 1 1 1 0 zinc-ribbon domain CTP_transf_like PF01467.26 PSC73874.1 - 4.5e-23 82.0 0.0 8.2e-23 81.2 0.0 1.4 1 1 0 1 1 1 1 Cytidylyltransferase-like Polyketide_cyc PF03364.20 PSC73877.1 - 3.6e-11 43.4 0.0 2.5e-10 40.7 0.0 2.0 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 PSC73877.1 - 0.00026 21.3 0.1 1.4 9.2 0.0 2.8 2 2 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport ABC_tran PF00005.27 PSC73878.1 - 4.3e-49 166.6 0.0 2.6e-24 86.3 0.0 2.4 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 PSC73878.1 - 4.3e-33 114.9 13.6 7.8e-18 64.7 0.0 2.1 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 PSC73878.1 - 7.9e-23 81.7 0.1 2.9e-08 33.9 0.0 4.3 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system DUF4162 PF13732.6 PSC73878.1 - 0.0015 19.2 0.0 1.3 9.8 0.0 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4162) SRP54 PF00448.22 PSC73878.1 - 0.0053 16.4 1.4 1 9.0 0.3 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_23 PF13476.6 PSC73878.1 - 0.0079 16.7 4.8 0.3 11.5 0.2 2.2 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 PSC73878.1 - 0.0089 15.8 2.3 0.052 13.3 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain MukB PF04310.12 PSC73878.1 - 0.093 12.5 5.9 0.45 10.3 2.5 2.3 2 0 0 2 2 2 0 MukB N-terminal ABC2_membrane PF01061.24 PSC73878.1 - 0.3 10.5 24.6 0.089 12.2 10.9 2.4 2 0 0 2 2 2 0 ABC-2 type transporter AAA_16 PF13191.6 PSC73878.1 - 0.45 10.9 5.1 27 5.1 0.2 3.8 3 0 0 3 3 3 0 AAA ATPase domain Abhydrolase_1 PF00561.20 PSC73879.1 - 2.9e-22 79.5 0.1 7.6e-17 61.8 0.1 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC73879.1 - 8e-15 54.8 0.0 1.3e-13 50.8 0.0 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PSC73879.1 - 1.3e-11 45.6 12.6 1.3e-11 45.6 12.6 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 PSC73879.1 - 1.4e-05 24.9 0.0 2.2e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_3 PF07859.13 PSC73879.1 - 7.3e-05 22.7 0.0 0.0016 18.3 0.0 2.4 2 0 0 2 2 2 1 alpha/beta hydrolase fold Ndr PF03096.14 PSC73879.1 - 0.0015 17.3 0.0 0.0028 16.4 0.0 1.3 1 0 0 1 1 1 1 Ndr family LIDHydrolase PF10230.9 PSC73879.1 - 0.0017 18.0 0.0 0.0048 16.5 0.0 1.6 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Peptidase_S9 PF00326.21 PSC73879.1 - 0.0031 17.0 0.0 0.018 14.5 0.0 2.0 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.7 PSC73879.1 - 0.028 14.2 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Thioesterase PF00975.20 PSC73879.1 - 0.054 13.6 0.4 1.2 9.2 0.2 2.3 2 0 0 2 2 2 0 Thioesterase domain PGAP1 PF07819.13 PSC73879.1 - 0.096 12.4 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein Redoxin PF08534.10 PSC73880.1 - 2.4e-36 124.6 0.0 2.7e-36 124.5 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 PSC73880.1 - 7e-11 42.1 0.0 8.4e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family MIP PF00230.20 PSC73881.1 - 2.7e-31 109.0 12.5 2.2e-30 106.0 12.5 2.3 1 1 0 1 1 1 1 Major intrinsic protein DUF1664 PF07889.12 PSC73881.1 - 0.086 12.9 0.7 0.19 11.8 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) FlaC_arch PF05377.11 PSC73881.1 - 0.7 10.3 2.6 0.75 10.2 0.5 2.0 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) ABC_tran PF00005.27 PSC73882.1 - 5.4e-21 75.5 0.0 1.1e-20 74.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter PPDK_N PF01326.19 PSC73882.1 - 1.1e-18 67.6 0.0 2.5e-12 46.7 0.0 4.0 2 2 1 4 4 4 3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain ABC2_membrane_3 PF12698.7 PSC73882.1 - 9.1e-16 57.9 14.9 1.3e-15 57.4 14.9 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PSC73882.1 - 1.1e-11 45.1 0.0 8.4e-08 32.4 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 PSC73882.1 - 0.0025 17.2 17.2 0.0049 16.3 17.2 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_2 PF12679.7 PSC73882.1 - 0.03 13.6 8.3 0.07 12.4 8.3 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_23 PF13476.6 PSC73882.1 - 0.098 13.1 0.6 0.21 12.0 0.2 1.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 PSC73882.1 - 0.23 11.4 0.1 0.44 10.4 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase IFRD_C PF04836.12 PSC73882.1 - 0.54 10.9 2.1 22 5.7 0.3 2.6 2 0 0 2 2 2 0 Interferon-related protein conserved region SUIM_assoc PF16619.5 PSC73882.1 - 0.72 10.0 14.6 1.6 8.9 1.1 3.5 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 DUF975 PF06161.11 PSC73882.1 - 0.88 9.3 6.0 1.4 8.6 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF975) DUF2569 PF10754.9 PSC73882.1 - 4 7.9 9.1 9.2 6.7 9.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) ABC_tran PF00005.27 PSC73883.1 - 5.5e-21 75.5 0.0 1.1e-20 74.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter PPDK_N PF01326.19 PSC73883.1 - 1.2e-18 67.5 0.0 2.5e-12 46.7 0.0 4.0 2 2 1 4 4 4 3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain ABC2_membrane_3 PF12698.7 PSC73883.1 - 9.2e-16 57.9 14.9 1.3e-15 57.4 14.9 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PSC73883.1 - 1.2e-11 45.0 0.0 8.5e-08 32.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 PSC73883.1 - 0.0026 17.2 17.2 0.005 16.3 17.2 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_2 PF12679.7 PSC73883.1 - 0.031 13.6 8.3 0.071 12.4 8.3 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_23 PF13476.6 PSC73883.1 - 0.1 13.1 0.6 0.22 12.0 0.2 1.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 PSC73883.1 - 0.23 11.4 0.1 0.45 10.4 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase IFRD_C PF04836.12 PSC73883.1 - 0.55 10.9 2.1 22 5.7 0.3 2.6 2 0 0 2 2 2 0 Interferon-related protein conserved region SUIM_assoc PF16619.5 PSC73883.1 - 0.75 9.9 14.6 1.6 8.9 1.1 3.5 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 DUF975 PF06161.11 PSC73883.1 - 0.89 9.3 6.0 1.4 8.6 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF975) DUF2569 PF10754.9 PSC73883.1 - 4 7.9 9.1 9.3 6.7 9.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) ABC_tran PF00005.27 PSC73884.1 - 5.7e-21 75.5 0.0 1.1e-20 74.5 0.0 1.4 1 0 0 1 1 1 1 ABC transporter PPDK_N PF01326.19 PSC73884.1 - 1.3e-18 67.4 0.0 2.6e-12 46.7 0.0 4.0 2 2 2 4 4 4 3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain ABC2_membrane_3 PF12698.7 PSC73884.1 - 9.5e-16 57.8 14.9 1.3e-15 57.3 14.9 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PSC73884.1 - 1.2e-11 45.0 0.0 8.7e-08 32.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane PF01061.24 PSC73884.1 - 0.0027 17.2 17.2 0.0051 16.3 17.2 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC2_membrane_2 PF12679.7 PSC73884.1 - 0.032 13.5 8.3 0.073 12.3 8.3 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_23 PF13476.6 PSC73884.1 - 0.1 13.1 0.6 0.22 12.0 0.2 1.7 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 PSC73884.1 - 0.24 11.3 0.1 0.46 10.4 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase IFRD_C PF04836.12 PSC73884.1 - 0.58 10.8 2.1 23 5.7 0.3 2.6 2 0 0 2 2 2 0 Interferon-related protein conserved region SUIM_assoc PF16619.5 PSC73884.1 - 0.81 9.8 14.6 1.6 8.8 1.1 3.5 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 DUF975 PF06161.11 PSC73884.1 - 0.92 9.3 6.0 1.5 8.6 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF975) DUF2569 PF10754.9 PSC73884.1 - 4.2 7.8 9.1 9.6 6.6 9.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2569) tRNA-synt_1c PF00749.21 PSC73885.1 - 3.1e-95 318.7 0.0 4e-95 318.3 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 PSC73885.1 - 6.4e-35 120.6 0.0 1e-34 119.9 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.6 PSC73885.1 - 0.0002 21.5 0.0 0.00065 19.9 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 PSC73885.1 - 0.00028 20.9 1.0 0.00087 19.3 1.0 1.9 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 PSC73885.1 - 0.0032 17.7 0.0 0.011 15.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 PSC73885.1 - 0.028 14.2 0.0 0.071 12.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain CDC45 PF02724.14 PSC73886.1 - 2.7 6.2 6.1 3.8 5.7 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 PSC73886.1 - 3.7 5.5 11.4 4.4 5.3 11.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi Paf1 PF03985.13 PSC73886.1 - 6.6 5.6 12.1 10 5.0 12.1 1.2 1 0 0 1 1 1 0 Paf1 Nop14 PF04147.12 PSC73886.1 - 9.6 4.3 12.0 13 3.8 12.0 1.1 1 0 0 1 1 1 0 Nop14-like family ALO PF04030.14 PSC73887.1 - 5.8e-12 46.0 0.0 1e-11 45.1 0.0 1.3 1 0 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 PSC73887.1 - 2.6e-10 40.2 0.0 8.6e-10 38.5 0.0 1.9 2 0 0 2 2 2 1 FAD binding domain DUF2389 PF09493.10 PSC73888.1 - 8.2e-08 32.8 1.2 8.2e-08 32.8 1.2 1.7 2 0 0 2 2 2 1 Tryptophan-rich protein (DUF2389) DUF2389 PF09493.10 PSC73889.1 - 8.2e-08 32.8 1.2 8.2e-08 32.8 1.2 1.7 2 0 0 2 2 2 1 Tryptophan-rich protein (DUF2389) TFIID_20kDa PF03847.13 PSC73890.1 - 6.8e-14 52.1 0.0 1.6e-13 50.9 0.0 1.6 2 0 0 2 2 2 1 Transcription initiation factor TFIID subunit A FAST_1 PF06743.15 PSC73891.1 - 8.7e-28 96.1 0.6 0.00017 21.5 0.0 10.8 10 4 3 13 13 13 8 FAST kinase-like protein, subdomain 1 DUF4050 PF13259.6 PSC73891.1 - 4.1 7.7 7.3 9.8 6.5 7.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) DUF647 PF04884.14 PSC73892.1 - 8.1e-72 241.7 0.0 1.1e-71 241.3 0.0 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis WD40 PF00400.32 PSC73893.1 - 8.7e-42 140.3 27.6 2.3e-06 28.2 0.4 12.2 13 0 0 13 13 13 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC73893.1 - 1.4e-16 60.5 0.5 0.015 15.6 0.0 7.4 8 1 1 9 9 9 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PSC73893.1 - 9.2e-08 31.4 0.3 0.034 13.1 0.0 3.7 4 0 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein IKI3 PF04762.12 PSC73893.1 - 0.13 10.3 0.0 0.25 9.3 0.0 1.4 1 0 0 1 1 1 0 IKI3 family Nup160 PF11715.8 PSC73893.1 - 0.65 8.6 1.2 12 4.5 0.1 2.1 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Pkinase PF00069.25 PSC73894.1 - 3.7e-71 239.6 0.0 5e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Glyco_hydro_9 PF00759.19 PSC73894.1 - 1e-67 229.4 5.4 1e-67 229.4 5.4 1.9 2 0 0 2 2 2 1 Glycosyl hydrolase family 9 Pkinase_Tyr PF07714.17 PSC73894.1 - 1.5e-38 132.6 0.0 2.1e-38 132.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC73894.1 - 3.4e-09 36.4 0.0 3.2e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 Kinase-like Pkinase_C PF00433.24 PSC73894.1 - 6.3e-06 26.8 0.0 1.7e-05 25.4 0.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Kazal_1 PF00050.21 PSC73894.1 - 7e-06 26.0 3.1 3e-05 23.9 3.1 2.1 1 0 0 1 1 1 1 Kazal-type serine protease inhibitor domain Pkinase_fungal PF17667.1 PSC73894.1 - 8.6e-06 24.8 0.0 1.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kazal_2 PF07648.15 PSC73894.1 - 0.0008 19.5 8.0 0.00096 19.2 6.2 2.0 2 0 0 2 2 2 1 Kazal-type serine protease inhibitor domain Kdo PF06293.14 PSC73894.1 - 0.001 18.5 0.0 0.0018 17.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PSC73894.1 - 0.002 17.2 0.1 0.0031 16.5 0.1 1.2 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PSC73894.1 - 0.002 18.1 0.0 0.0046 16.9 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_Tyr PF07714.17 PSC73895.1 - 3.4e-49 167.5 0.0 2e-48 164.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC73895.1 - 1.5e-39 136.0 0.0 3.1e-39 134.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 PSC73895.1 - 0.018 15.0 0.0 0.018 15.0 0.0 3.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF2383 PF09537.10 PSC73895.1 - 0.04 14.3 0.6 0.099 13.0 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Haspin_kinase PF12330.8 PSC73895.1 - 0.11 11.4 0.0 0.28 10.1 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 PSC73895.1 - 0.18 11.1 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like WD40 PF00400.32 PSC73895.1 - 0.31 12.0 1.2 13 6.9 0.3 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat HBM PF16591.5 PSC73895.1 - 1.1 8.6 6.9 0.13 11.7 2.1 1.8 2 0 0 2 2 2 0 Helical bimodular sensor domain CHASE3 PF05227.13 PSC73895.1 - 6.3 6.7 7.7 0.36 10.7 1.2 2.1 2 0 0 2 2 2 0 CHASE3 domain Pkinase_Tyr PF07714.17 PSC73896.1 - 3.4e-49 167.5 0.0 2e-48 164.9 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC73896.1 - 1.5e-39 136.0 0.0 3.1e-39 134.9 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 PSC73896.1 - 0.018 15.0 0.0 0.018 15.0 0.0 3.3 3 0 0 3 3 3 0 Phosphotransferase enzyme family DUF2383 PF09537.10 PSC73896.1 - 0.04 14.3 0.6 0.099 13.0 0.2 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2383) Haspin_kinase PF12330.8 PSC73896.1 - 0.11 11.4 0.0 0.28 10.1 0.0 1.5 2 0 0 2 2 2 0 Haspin like kinase domain Kinase-like PF14531.6 PSC73896.1 - 0.18 11.1 0.0 0.34 10.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like WD40 PF00400.32 PSC73896.1 - 0.3 12.0 1.2 13 6.9 0.3 3.9 3 0 0 3 3 3 0 WD domain, G-beta repeat HBM PF16591.5 PSC73896.1 - 1.1 8.6 6.9 0.13 11.7 2.1 1.8 2 0 0 2 2 2 0 Helical bimodular sensor domain CHASE3 PF05227.13 PSC73896.1 - 6.2 6.7 7.7 0.36 10.7 1.2 2.1 2 0 0 2 2 2 0 CHASE3 domain Apolipoprotein PF01442.18 PSC73897.1 - 3.6e-07 30.3 76.4 7e-05 22.8 25.2 5.0 3 1 1 4 4 4 3 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 PSC73897.1 - 4.1 7.5 21.4 11 6.1 1.6 5.1 3 2 0 4 4 4 0 Apolipophorin-III precursor (apoLp-III) SAP PF02037.27 PSC73898.1 - 0.029 14.1 0.0 0.039 13.7 0.0 1.3 1 0 0 1 1 1 0 SAP domain Dickkopf_N PF04706.12 PSC73899.1 - 0.17 12.4 12.0 0.42 11.1 12.0 1.7 1 0 0 1 1 1 0 Dickkopf N-terminal cysteine-rich region UPF0506 PF11703.8 PSC73899.1 - 2.4 8.6 15.0 2.5 8.6 4.6 2.3 1 1 1 2 2 2 0 UPF0506 PMSR PF01625.21 PSC73900.1 - 7e-51 172.4 0.2 1.1e-50 171.8 0.2 1.2 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase Ribonuclease_T2 PF00445.18 PSC73900.1 - 1.6e-08 35.0 0.0 2.6e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family HA PF03457.14 PSC73901.1 - 1.1e-32 112.2 30.8 4.6e-16 58.9 0.1 6.9 7 0 0 7 7 7 5 Helicase associated domain HA PF03457.14 PSC73902.1 - 8.4e-33 112.5 30.8 4.5e-16 58.9 0.1 6.9 7 0 0 7 7 7 5 Helicase associated domain HA PF03457.14 PSC73903.1 - 8.5e-33 112.5 30.8 4.5e-16 58.9 0.1 6.9 7 0 0 7 7 7 5 Helicase associated domain UPF0220 PF05255.11 PSC73905.1 - 5e-18 65.2 2.4 2.9e-17 62.7 2.4 1.8 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF2339 PF10101.9 PSC73905.1 - 0.0069 15.0 3.2 0.01 14.5 3.2 1.2 1 1 0 1 1 1 1 Predicted membrane protein (DUF2339) Peptidase_S8 PF00082.22 PSC73906.1 - 1.7e-17 63.7 6.2 1.8e-12 47.2 0.5 3.3 1 1 1 2 2 2 2 Subtilase family FKBP_C PF00254.28 PSC73907.1 - 1.8e-10 41.0 0.0 3e-10 40.3 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Lipase_3 PF01764.25 PSC73908.1 - 2.5e-51 173.3 0.0 4.7e-25 88.1 0.0 2.5 2 0 0 2 2 2 2 Lipase (class 3) EamA PF00892.20 PSC73908.1 - 5.6e-11 42.8 45.8 2.5e-10 40.7 13.0 4.1 3 0 0 3 3 3 2 EamA-like transporter family DUF2974 PF11187.8 PSC73908.1 - 7.6e-06 25.6 2.0 1.4 8.4 0.0 4.1 4 0 0 4 4 4 2 Protein of unknown function (DUF2974) PGAP1 PF07819.13 PSC73908.1 - 0.0038 17.0 0.0 3.4 7.3 0.0 2.3 2 0 0 2 2 2 2 PGAP1-like protein Hydrolase_4 PF12146.8 PSC73908.1 - 0.011 15.0 0.1 4.7 6.4 0.0 2.5 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_5 PF12695.7 PSC73908.1 - 0.1 12.3 0.1 20 4.9 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family Aldo_ket_red PF00248.21 PSC73909.1 - 2.5e-61 207.5 0.0 2.8e-61 207.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF2399 PF09664.10 PSC73909.1 - 0.022 14.6 0.1 0.086 12.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function C-terminus (DUF2399) HAD_2 PF13419.6 PSC73910.1 - 8.2e-19 68.4 0.0 1.2e-18 67.8 0.0 1.3 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PSC73910.1 - 9e-14 52.3 0.0 2e-13 51.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PSC73910.1 - 2.2e-08 34.0 0.0 5.7e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 PSC73910.1 - 0.00033 21.1 0.1 0.00054 20.4 0.1 1.5 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 PSC73910.1 - 0.009 16.1 0.0 0.024 14.7 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase RNase_T PF00929.24 PSC73911.1 - 5.7e-22 79.0 0.0 7.5e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Exonuclease zf-GRF PF06839.12 PSC73911.1 - 1.8e-08 34.3 2.9 2.9e-08 33.7 2.9 1.3 1 0 0 1 1 1 1 GRF zinc finger Arginosuc_synth PF00764.19 PSC73912.1 - 3.7e-155 517.0 0.0 4.3e-155 516.8 0.0 1.0 1 0 0 1 1 1 1 Arginosuccinate synthase QueC PF06508.13 PSC73912.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.2 1 0 0 1 1 1 1 Queuosine biosynthesis protein QueC Asn_synthase PF00733.21 PSC73912.1 - 0.0024 17.6 0.0 0.0036 17.0 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase TPR_12 PF13424.6 PSC73913.1 - 3e-07 30.6 0.1 0.00016 21.9 0.1 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.6 PSC73913.1 - 0.002 17.9 1.0 0.33 10.9 0.0 4.1 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 PSC73913.1 - 0.017 15.2 0.0 4.3 7.7 0.0 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat PTPA PF03095.15 PSC73914.1 - 1.3e-120 402.4 0.0 1.6e-120 402.2 0.0 1.0 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein CASP_C PF08172.12 PSC73915.1 - 3.9e-54 183.7 18.5 5e-52 176.8 0.0 4.8 2 1 3 5 5 5 1 CASP C terminal PNTB PF02233.16 PSC73915.1 - 0.024 13.6 0.8 0.039 12.9 0.1 1.6 2 0 0 2 2 2 0 NAD(P) transhydrogenase beta subunit DUF2935 PF11155.8 PSC73915.1 - 0.23 11.8 3.4 4.9 7.5 0.0 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Bacillus_HBL PF05791.11 PSC73915.1 - 1.6 8.5 0.0 1.6 8.5 0.0 3.6 3 1 1 4 4 4 0 Bacillus haemolytic enterotoxin (HBL) DUF4407 PF14362.6 PSC73915.1 - 1.7 7.9 55.8 4.9 6.4 2.6 4.4 2 2 1 3 3 3 0 Domain of unknown function (DUF4407) Herpes_UL6 PF01763.16 PSC73915.1 - 2.6 6.4 8.2 7.2 5.0 8.2 1.8 1 0 0 1 1 1 0 Herpesvirus UL6 like Med30 PF11315.8 PSC73915.1 - 4 7.6 17.8 1.5 9.0 6.2 3.1 2 1 1 3 3 3 0 Mediator complex subunit 30 TRP PF06011.12 PSC73916.1 - 0.28 9.9 0.9 0.39 9.4 0.9 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel PIN_6 PF17146.4 PSC73917.1 - 1.5e-24 86.3 0.2 2.6e-24 85.5 0.2 1.4 1 0 0 1 1 1 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 PSC73917.1 - 5.9e-23 80.8 0.1 1e-22 80.1 0.1 1.4 1 0 0 1 1 1 1 Nin one binding (NOB1) Zn-ribbon like zf-NADH-PPase PF09297.11 PSC73917.1 - 1.3 8.8 5.0 0.86 9.3 0.1 2.9 3 0 0 3 3 3 0 NADH pyrophosphatase zinc ribbon domain SDA1 PF05285.12 PSC73917.1 - 2.8 7.3 16.0 1.6 8.1 13.1 1.8 2 0 0 2 2 2 0 SDA1 Pectate_lyase_3 PF12708.7 PSC73918.1 - 6.5e-21 75.2 1.6 1.8e-20 73.7 0.1 2.3 2 1 0 2 2 2 1 Pectate lyase superfamily protein End_N_terminal PF12218.8 PSC73918.1 - 0.024 14.3 0.1 0.055 13.2 0.1 1.6 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase DUF2537 PF10801.8 PSC73918.1 - 0.67 10.2 8.0 1.2 9.4 0.7 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2537) Pkinase PF00069.25 PSC73919.1 - 6.5e-43 147.0 0.0 5.1e-31 108.0 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73919.1 - 3.8e-34 118.2 0.0 6.4e-25 87.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase HAD_2 PF13419.6 PSC73919.1 - 1.2e-18 67.8 0.0 1.9e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase DSPc PF00782.20 PSC73919.1 - 9.4e-13 48.1 0.0 1.5e-11 44.2 0.0 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Hydrolase PF00702.26 PSC73919.1 - 9.8e-13 48.9 1.6 5.6e-12 46.4 0.1 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Pkinase_fungal PF17667.1 PSC73919.1 - 1e-06 27.8 0.2 1.7e-06 27.1 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Hydrolase_like PF13242.6 PSC73919.1 - 1.3e-05 25.1 0.2 5.6e-05 23.1 0.1 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like ABC1 PF03109.16 PSC73919.1 - 0.0036 17.5 0.0 0.0081 16.3 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Init_tRNA_PT PF04179.12 PSC73919.1 - 0.16 12.3 0.2 0.54 10.6 0.0 1.9 2 0 0 2 2 2 0 Rit1 DUSP-like domain Med15 PF09606.10 PSC73919.1 - 1.1 7.9 9.8 1.9 7.1 9.8 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_M16_M PF16187.5 PSC73920.1 - 9.7e-83 277.7 0.1 1.4e-82 277.1 0.1 1.3 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 NUDIX_2 PF13869.6 PSC73920.1 - 8.9e-72 240.6 0.0 1.4e-71 240.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotide hydrolase Peptidase_M16 PF00675.20 PSC73920.1 - 3.7e-35 121.1 0.0 7.4e-35 120.1 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 PSC73920.1 - 5.5e-27 95.0 0.0 1.3e-17 64.5 0.0 2.5 2 0 0 2 2 2 2 Peptidase M16 inactive domain Ribosomal_L12 PF00542.19 PSC73920.1 - 1.2e-24 86.4 7.5 1.2e-24 86.4 7.5 2.7 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 PSC73920.1 - 2.1e-08 33.7 2.5 2.1e-08 33.7 2.5 8.1 6 2 1 7 7 7 1 Ribosomal protein L7/L12 dimerisation domain NUDIX PF00293.28 PSC73920.1 - 0.08 13.0 2.0 0.17 11.9 0.0 2.7 2 0 0 2 2 2 0 NUDIX domain TFIIA PF03153.13 PSC73920.1 - 1.3 9.0 18.3 0.17 11.9 13.9 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Histone PF00125.24 PSC73921.1 - 3.3e-16 59.8 0.3 4.4e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RP-C PF03428.13 PSC73921.1 - 0.017 14.8 0.7 1.3 8.7 0.0 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain DnaJ PF00226.31 PSC73921.1 - 0.017 15.2 0.0 0.044 13.9 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain CBFD_NFYB_HMF PF00808.23 PSC73921.1 - 0.023 14.9 0.1 0.023 14.9 0.1 1.7 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Pkinase_Tyr PF07714.17 PSC73922.1 - 5.6e-47 160.2 0.0 7.9e-47 159.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC73922.1 - 3.8e-39 134.6 0.0 5e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PSC73922.1 - 2.2e-09 36.9 0.8 6.3e-06 25.9 0.0 2.7 2 1 1 3 3 3 2 Leucine rich repeat LRR_4 PF12799.7 PSC73922.1 - 4.1e-06 27.0 0.0 0.016 15.6 0.0 2.5 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) FTA2 PF13095.6 PSC73922.1 - 0.0042 16.7 0.0 0.046 13.3 0.0 2.0 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Kinase-like PF14531.6 PSC73922.1 - 0.0074 15.6 0.0 0.012 14.9 0.0 1.2 1 0 0 1 1 1 1 Kinase-like LRR_6 PF13516.6 PSC73922.1 - 0.024 14.7 0.9 51 4.3 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat APH PF01636.23 PSC73922.1 - 0.043 13.7 1.1 0.37 10.7 0.0 2.4 2 0 0 2 2 2 0 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PSC73922.1 - 0.052 12.5 0.0 0.091 11.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain LRR_1 PF00560.33 PSC73922.1 - 0.07 13.7 0.0 1.2e+02 3.9 0.0 3.7 3 0 0 3 3 3 0 Leucine Rich Repeat LRRNT_2 PF08263.12 PSC73922.1 - 0.075 13.4 0.2 0.23 11.8 0.2 1.8 1 0 0 1 1 1 0 Leucine rich repeat N-terminal domain Ndufs5 PF10200.9 PSC73923.1 - 0.006 16.8 1.2 0.0081 16.4 1.2 1.3 1 1 0 1 1 1 1 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa Pet191_N PF10203.9 PSC73923.1 - 0.012 15.8 0.8 0.016 15.5 0.8 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 GCK PF07802.11 PSC73923.1 - 0.015 15.7 0.2 0.02 15.3 0.2 1.2 1 0 0 1 1 1 0 GCK domain UPF0203 PF05254.12 PSC73923.1 - 0.054 13.7 3.0 0.73 10.1 3.2 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) COX6B PF02297.17 PSC73923.1 - 0.35 11.1 4.7 0.47 10.7 3.0 1.7 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb PseudoU_synth_2 PF00849.22 PSC73924.1 - 6.2e-27 94.6 0.1 2e-26 93.0 0.0 1.9 2 0 0 2 2 2 1 RNA pseudouridylate synthase Epimerase PF01370.21 PSC73924.1 - 8.1e-09 35.3 0.0 0.0025 17.3 0.0 2.4 1 1 1 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PSC73924.1 - 0.0007 19.1 0.4 0.0042 16.5 0.0 2.2 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Phostensin_N PF13916.6 PSC73924.1 - 5.5 7.4 14.6 0.14 12.5 7.5 2.2 2 0 0 2 2 2 0 PP1-regulatory protein, Phostensin N-terminal Redoxin PF08534.10 PSC73925.1 - 8.1e-29 100.2 0.0 9.6e-29 100.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 PSC73925.1 - 5.1e-14 52.3 0.0 6.1e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family SBP_bac_3 PF00497.20 PSC73926.1 - 5.4e-21 75.0 0.0 1e-20 74.2 0.0 1.4 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 PSC73926.1 - 2.4e-17 63.2 0.0 6.9e-17 61.7 0.0 1.8 1 1 1 2 2 2 1 Ligand-gated ion channel Tmemb_cc2 PF10267.9 PSC73926.1 - 1.6 7.8 5.3 14 4.7 0.0 2.1 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein IATP PF04568.12 PSC73926.1 - 9.8 6.7 5.9 4.5 7.8 3.1 1.8 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP zf-C3HC4_3 PF13920.6 PSC73927.1 - 2.3e-08 33.8 4.9 2.3e-08 33.8 4.9 4.6 5 0 0 5 5 5 2 Zinc finger, C3HC4 type (RING finger) F-box PF00646.33 PSC73927.1 - 2.6e-08 33.5 0.2 6.9e-07 29.0 0.0 2.7 2 0 0 2 2 2 1 F-box domain zf-C3HC4_2 PF13923.6 PSC73927.1 - 6.6e-08 32.3 8.9 6.6e-08 32.3 8.9 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) F-box-like PF12937.7 PSC73927.1 - 4.8e-07 29.6 1.7 4.8e-07 29.6 1.7 2.9 3 0 0 3 3 3 1 F-box-like zf-RING_UBOX PF13445.6 PSC73927.1 - 5.1e-07 29.6 17.1 0.00055 19.9 3.4 3.7 2 1 1 3 3 3 2 RING-type zinc-finger zf-C3HC4 PF00097.25 PSC73927.1 - 3.9e-06 26.6 21.6 3.3e-05 23.7 6.6 3.6 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) ZZ PF00569.17 PSC73927.1 - 4.6e-06 26.3 1.8 4.6e-06 26.3 1.8 2.6 3 0 0 3 3 3 1 Zinc finger, ZZ type zf-RING_5 PF14634.6 PSC73927.1 - 5.3e-05 23.1 26.0 0.00068 19.5 5.7 4.3 4 1 0 4 4 4 2 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PSC73927.1 - 7.1e-05 22.9 24.3 0.0011 19.1 1.4 3.4 3 0 0 3 3 3 2 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 PSC73927.1 - 9.5e-05 22.7 8.6 9.5e-05 22.7 8.6 3.9 3 1 0 3 3 2 1 Ring finger domain Prok-RING_4 PF14447.6 PSC73927.1 - 0.00091 19.0 7.1 0.00091 19.0 7.1 3.9 4 0 0 4 4 3 2 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 PSC73927.1 - 0.0018 18.1 2.5 0.0018 18.1 2.5 2.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 PSC73927.1 - 0.0027 17.4 7.5 0.0027 17.4 7.5 4.0 4 0 0 4 4 4 1 RING/Ubox like zinc-binding domain zf-H2C2_2 PF13465.6 PSC73927.1 - 0.48 11.0 3.3 89 3.8 0.0 4.1 4 0 0 4 4 4 0 Zinc-finger double domain Presenilin PF01080.17 PSC73927.1 - 0.86 8.3 4.4 1.3 7.7 4.4 1.2 1 0 0 1 1 1 0 Presenilin zf-RING_10 PF16685.5 PSC73927.1 - 3.5 7.8 20.3 1.9 8.7 3.4 3.0 2 0 0 2 2 2 0 zinc RING finger of MSL2 Pro_isomerase PF00160.21 PSC73928.1 - 7.4e-46 156.3 0.2 8.7e-46 156.1 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD HEAT PF02985.22 PSC73929.1 - 0.038 14.3 19.7 0.15 12.4 1.0 6.5 5 0 0 5 5 5 0 HEAT repeat Arm PF00514.23 PSC73929.1 - 0.039 14.0 1.9 0.46 10.6 0.1 4.1 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat UTP25 PF06862.12 PSC73930.1 - 1.3e-147 492.5 0.0 1.5e-147 492.2 0.0 1.0 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF1639 PF07797.14 PSC73931.1 - 0.033 14.2 0.2 0.059 13.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1639) Peptidase_S24 PF00717.23 PSC73932.1 - 6.5e-08 32.4 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Peptidase S24-like Peptidase_S26 PF10502.9 PSC73932.1 - 2.1e-06 27.6 0.1 0.00018 21.3 0.0 2.7 2 1 1 3 3 3 2 Signal peptidase, peptidase S26 EamA PF00892.20 PSC73933.1 - 2.9e-18 66.4 58.5 3.9e-08 33.5 9.5 4.0 4 0 0 4 4 4 4 EamA-like transporter family EamA PF00892.20 PSC73934.1 - 1e-14 54.9 56.3 4e-08 33.5 9.5 4.7 4 1 0 4 4 4 4 EamA-like transporter family Hexapep PF00132.24 PSC73935.1 - 1.3e-12 46.9 11.1 0.00014 21.4 0.2 4.3 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 PSC73935.1 - 0.028 14.2 11.0 0.08 12.7 1.2 4.1 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase RVT_2 PF07727.14 PSC73936.1 - 2.6e-72 243.4 0.0 3.3e-72 243.0 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Crr6 PF08847.11 PSC73936.1 - 0.053 13.2 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 Chlororespiratory reduction 6 DAP_B PF07930.12 PSC73936.1 - 0.15 12.1 0.0 0.3 11.0 0.0 1.4 1 0 0 1 1 1 0 D-aminopeptidase, domain B Fasciclin PF02469.22 PSC73937.1 - 1.6e-10 41.3 0.0 4.9e-10 39.7 0.0 1.7 1 1 0 1 1 1 1 Fasciclin domain PAN_4 PF14295.6 PSC73937.1 - 5.8e-06 26.1 5.9 5.8e-06 26.1 5.9 2.4 2 0 0 2 2 2 1 PAN domain TPR_1 PF00515.28 PSC73938.1 - 1.2e-21 75.6 5.0 2e-05 24.2 0.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 PSC73938.1 - 1.4e-20 71.6 9.8 7.5e-05 22.6 0.2 5.8 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 PSC73938.1 - 2.3e-20 72.0 6.7 3e-05 23.6 0.1 6.6 6 0 0 6 6 6 5 TPR repeat TPR_17 PF13431.6 PSC73938.1 - 7.1e-16 57.4 11.7 0.0033 17.7 0.1 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 PSC73938.1 - 1.2e-15 57.9 34.1 7.5e-07 29.7 1.7 7.9 6 1 3 9 9 8 5 Tetratricopeptide repeat TPR_8 PF13181.6 PSC73938.1 - 1.3e-13 50.0 2.6 0.11 12.8 0.2 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_14 PF13428.6 PSC73938.1 - 4.2e-10 39.6 42.9 0.0041 17.8 0.7 9.4 6 2 4 10 10 8 5 Tetratricopeptide repeat TPR_7 PF13176.6 PSC73938.1 - 7.2e-07 28.8 7.0 0.14 12.2 0.1 5.2 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 PSC73938.1 - 4.5e-06 26.9 19.9 0.0008 19.7 1.1 4.8 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_9 PF13371.6 PSC73938.1 - 0.00035 20.7 4.9 0.0038 17.3 0.2 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 PSC73938.1 - 0.00039 20.2 12.7 0.83 9.6 0.2 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_20 PF14561.6 PSC73938.1 - 0.00086 19.6 12.8 0.38 11.1 1.1 4.8 3 2 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 PSC73938.1 - 0.0017 18.8 0.8 0.0017 18.8 0.8 5.9 5 1 1 6 6 4 3 Tetratricopeptide repeat TPR_6 PF13174.6 PSC73938.1 - 0.0019 18.7 1.8 26 5.7 0.1 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat LIDHydrolase PF10230.9 PSC73939.1 - 2e-26 93.1 0.0 2.3e-25 89.6 0.0 2.0 1 1 0 1 1 1 1 Lipid-droplet associated hydrolase DUF393 PF04134.12 PSC73939.1 - 4.8e-23 82.6 1.3 1.3e-22 81.3 0.2 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF393 Hydrolase_4 PF12146.8 PSC73939.1 - 0.0038 16.5 0.2 0.0067 15.7 0.2 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PSC73939.1 - 0.13 12.9 23.4 1.2 9.7 23.3 2.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF900 PF05990.12 PSC73939.1 - 0.15 11.6 0.2 0.45 10.0 0.0 1.8 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) APC_basic PF05956.11 PSC73939.1 - 0.5 9.8 5.8 0.75 9.2 5.8 1.2 1 0 0 1 1 1 0 APC basic domain ATG13 PF10033.9 PSC73940.1 - 3.1e-25 89.3 0.0 8.5e-17 61.6 0.0 2.3 1 1 1 2 2 2 2 Autophagy-related protein 13 Mg_trans_NIPA PF05653.14 PSC73940.1 - 6.2e-25 87.9 18.1 2.7e-24 85.8 18.1 1.8 1 1 0 1 1 1 1 Magnesium transporter NIPA DUF3810 PF12725.7 PSC73940.1 - 0.074 12.4 4.0 0.08 12.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3810) EamA PF00892.20 PSC73940.1 - 2.1 8.5 20.8 0.56 10.4 2.9 2.5 2 0 0 2 2 2 0 EamA-like transporter family NAD_binding_5 PF07994.12 PSC73941.1 - 8.7e-139 462.4 0.0 1e-138 462.2 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 PSC73941.1 - 5.2e-47 158.6 0.1 8.6e-47 157.9 0.1 1.4 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase ubiquitin PF00240.23 PSC73942.1 - 1.9e-15 56.4 0.0 3.9e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PSC73942.1 - 0.00016 21.4 0.0 0.00047 19.9 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PSC73942.1 - 0.00052 20.4 0.0 0.0015 18.9 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 PSC73942.1 - 0.0057 16.6 0.0 0.01 15.7 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 PSC73942.1 - 0.0058 17.0 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain DUF3682 PF12446.8 PSC73942.1 - 0.64 10.5 13.3 0.06 13.8 7.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) ubiquitin PF00240.23 PSC73943.1 - 1.8e-15 56.4 0.0 3.7e-15 55.4 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 PSC73943.1 - 0.00016 21.5 0.0 0.00046 20.0 0.0 1.8 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 PSC73943.1 - 0.0005 20.5 0.0 0.0014 19.0 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 PSC73943.1 - 0.0055 16.6 0.0 0.01 15.8 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 PSC73943.1 - 0.0056 17.0 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain DUF3682 PF12446.8 PSC73943.1 - 0.45 11.0 11.7 0.058 13.9 7.7 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3682) Cyclin_N PF00134.23 PSC73944.1 - 0.036 13.8 0.3 0.055 13.2 0.0 1.5 2 0 0 2 2 2 0 Cyclin, N-terminal domain ANAPC4_WD40 PF12894.7 PSC73945.1 - 9.7e-10 38.6 0.0 0.0057 16.9 0.0 4.5 3 2 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PSC73945.1 - 1e-08 35.6 0.1 0.15 13.0 0.1 6.2 7 0 0 7 7 7 2 WD domain, G-beta repeat Sucrose_synth PF00862.19 PSC73946.1 - 1.6e-229 762.8 0.0 2.1e-229 762.4 0.0 1.1 1 0 0 1 1 1 1 Sucrose synthase Glycos_transf_1 PF00534.20 PSC73946.1 - 3.2e-31 108.2 0.0 7e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PSC73946.1 - 1.4e-08 35.2 0.0 3.4e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 PSC73946.1 - 1.7e-05 25.1 0.0 4.7e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Sas10 PF09368.10 PSC73947.1 - 2.6e-26 91.9 5.4 7.4e-26 90.4 5.4 1.9 1 0 0 1 1 1 1 Sas10 C-terminal domain Sas10_Utp3 PF04000.15 PSC73947.1 - 4e-18 65.8 0.0 1.3e-17 64.2 0.0 2.0 1 0 0 1 1 1 1 Sas10/Utp3/C1D family DUF1724 PF08350.10 PSC73948.1 - 0.049 13.8 0.0 0.082 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1724) RNA_pol_Rpb1_5 PF04998.17 PSC73949.1 - 4.7e-89 298.3 0.0 9.1e-89 297.4 0.0 1.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 PSC73949.1 - 2.6e-82 276.7 0.0 3.7e-82 276.1 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 PSC73949.1 - 2e-72 242.8 0.0 3.8e-72 241.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 PSC73949.1 - 7.2e-33 113.7 0.0 1.4e-32 112.8 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 PSC73949.1 - 2.2e-29 101.6 0.0 4.7e-29 100.5 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 zf-tcix PF14952.6 PSC73949.1 - 0.047 13.3 2.4 0.13 11.9 2.4 1.7 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Rpr2 PF04032.16 PSC73949.1 - 3.5 8.0 6.5 3.3 8.1 2.1 2.5 2 0 0 2 2 2 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain MMR_HSR1 PF01926.23 PSC73950.1 - 1.5e-18 66.9 0.0 7.7e-18 64.6 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP-bdg_N PF13167.6 PSC73950.1 - 2.5e-17 63.3 0.0 7.7e-17 61.8 0.0 1.9 1 0 0 1 1 1 1 GTP-binding GTPase N-terminal GTP-bdg_M PF16360.5 PSC73950.1 - 8.4e-17 61.5 15.8 5.4e-16 58.9 15.8 2.4 1 1 0 1 1 1 1 GTP-binding GTPase Middle Region Dynamin_N PF00350.23 PSC73950.1 - 0.0017 18.4 0.1 0.0097 16.0 0.1 2.1 2 0 0 2 2 2 1 Dynamin family FeoB_N PF02421.18 PSC73950.1 - 0.068 12.7 0.4 0.29 10.7 0.2 2.2 2 1 0 2 2 2 0 Ferrous iron transport protein B ABC_tran PF00005.27 PSC73950.1 - 0.08 13.5 0.0 0.25 11.9 0.0 1.9 2 0 0 2 2 2 0 ABC transporter AAA_21 PF13304.6 PSC73950.1 - 0.1 12.4 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 PSC73950.1 - 0.11 13.0 0.1 0.22 12.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain SUIM_assoc PF16619.5 PSC73950.1 - 0.64 10.1 5.7 1.5 9.0 5.7 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 OmdA PF13376.6 PSC73951.1 - 2.1e-20 72.5 0.1 4.5e-20 71.4 0.1 1.6 1 0 0 1 1 1 1 Bacteriocin-protection, YdeI or OmpD-Associated Lyase_1 PF00206.20 PSC73952.1 - 4.3e-63 213.6 0.0 6.8e-63 212.9 0.0 1.3 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 PSC73952.1 - 5.2e-49 165.1 0.0 1.9e-48 163.3 0.0 2.0 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminal Ion_trans PF00520.31 PSC73953.1 - 1.5e-18 67.0 28.7 3.8e-10 39.4 12.6 2.3 2 0 0 2 2 2 2 Ion transport protein PKD_channel PF08016.12 PSC73953.1 - 9.7e-06 24.5 24.1 0.00031 19.6 7.2 3.6 2 1 1 3 3 3 3 Polycystin cation channel ATPase_gene1 PF09527.10 PSC73953.1 - 0.27 11.4 5.6 9.3 6.5 0.2 3.4 2 0 0 2 2 2 0 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter DSS1_SEM1 PF05160.13 PSC73955.1 - 9.6e-19 67.2 17.0 1.2e-18 67.0 17.0 1.1 1 0 0 1 1 1 1 DSS1/SEM1 family DUF2947 PF11163.8 PSC73955.1 - 0.013 15.4 5.6 0.014 15.3 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2947) AAA_6 PF12774.7 PSC73956.1 - 1.1e-148 494.6 0.0 6.1e-147 488.8 0.0 2.8 3 0 0 3 3 3 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 PSC73956.1 - 7.1e-145 483.8 0.0 2.7e-144 481.9 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 PSC73956.1 - 1.1e-118 396.8 0.9 1.1e-118 396.8 0.9 2.6 3 0 0 3 3 3 1 Dynein heavy chain, N-terminal region 2 AAA_8 PF12780.7 PSC73956.1 - 1.3e-90 303.2 0.0 9.1e-90 300.5 0.0 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 PSC73956.1 - 1.6e-86 290.3 0.0 6.4e-86 288.3 0.0 2.1 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_9 PF12781.7 PSC73956.1 - 1.3e-84 282.7 0.4 2.6e-84 281.7 0.4 1.5 1 0 0 1 1 1 1 ATP-binding dynein motor region AAA_7 PF12775.7 PSC73956.1 - 1.9e-61 206.8 0.0 9.6e-56 188.1 0.0 4.9 5 0 0 5 5 5 2 P-loop containing dynein motor region MT PF12777.7 PSC73956.1 - 6.4e-50 170.1 10.8 1.4e-49 169.0 10.8 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 PSC73956.1 - 2.3e-48 164.1 0.0 4.8e-48 163.1 0.0 1.6 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain Dynein_heavy PF03028.15 PSC73956.1 - 6.6e-38 129.5 0.0 1.1e-36 125.5 0.0 3.0 3 0 0 3 3 2 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 PSC73956.1 - 4.9e-21 75.1 0.0 2.7e-20 72.7 0.0 2.5 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 PSC73956.1 - 1.9e-19 70.0 0.0 7e-07 29.3 0.0 6.2 5 1 0 5 5 5 3 AAA domain (dynein-related subfamily) AAA_lid_1 PF17857.1 PSC73956.1 - 7.3e-16 58.2 0.0 2.1e-09 37.5 0.0 2.8 2 0 0 2 2 2 2 AAA+ lid domain AAA PF00004.29 PSC73956.1 - 3.3e-07 30.8 0.2 1 9.8 0.0 4.9 4 0 0 4 4 4 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PSC73956.1 - 4.8e-06 27.0 19.1 0.67 10.3 0.0 8.5 8 0 0 8 8 7 3 AAA ATPase domain AAA_19 PF13245.6 PSC73956.1 - 0.00046 20.5 11.6 0.59 10.5 0.1 5.4 5 0 0 5 5 5 2 AAA domain AAA_22 PF13401.6 PSC73956.1 - 0.0023 18.2 5.1 31 4.8 0.1 6.0 5 0 0 5 5 5 0 AAA domain AAA_29 PF13555.6 PSC73956.1 - 0.0041 16.8 3.1 0.011 15.4 0.0 2.8 3 0 0 3 3 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 PSC73956.1 - 0.019 15.5 0.4 13 6.4 0.0 4.0 3 0 0 3 3 3 0 AAA domain DUF697 PF05128.12 PSC73956.1 - 0.081 12.6 0.0 0.081 12.6 0.0 2.3 2 0 0 2 2 1 0 Domain of unknown function (DUF697) IIGP PF05049.13 PSC73956.1 - 0.1 11.6 0.0 0.4 9.7 0.0 2.0 2 0 0 2 2 2 0 Interferon-inducible GTPase (IIGP) AAA_33 PF13671.6 PSC73956.1 - 0.12 12.5 1.8 26 5.0 0.0 4.6 4 0 0 4 4 3 0 AAA domain Filament PF00038.21 PSC73956.1 - 0.42 10.2 22.2 0.027 14.1 2.2 3.8 3 0 0 3 3 3 0 Intermediate filament protein Spc7 PF08317.11 PSC73956.1 - 6.4 5.6 20.5 4.1 6.2 2.4 3.9 3 0 0 3 3 3 0 Spc7 kinetochore protein BAT2_N PF07001.11 PSC73958.1 - 2.8e-08 34.5 4.9 2.8e-08 34.5 4.9 5.5 5 2 1 6 6 6 1 BAT2 N-terminus HrpA_pilin PF09589.10 PSC73958.1 - 0.19 12.5 3.0 0.37 11.5 1.7 2.2 2 0 0 2 2 2 0 HrpA pilus formation protein SIS PF01380.22 PSC73959.1 - 1.6e-54 183.2 0.5 3e-31 108.0 0.2 2.3 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 PSC73959.1 - 1.6e-15 57.5 0.0 3.3e-15 56.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 PSC73959.1 - 1.1e-11 44.8 0.0 2.8e-11 43.4 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 PSC73959.1 - 0.00027 19.9 0.0 0.00059 18.8 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferases class-II SIS_2 PF13580.6 PSC73959.1 - 0.016 15.2 0.0 0.39 10.7 0.0 2.6 2 1 0 2 2 2 0 SIS domain DUF2529 PF10740.9 PSC73959.1 - 0.025 14.2 0.8 1.1 8.8 0.0 3.1 3 1 0 4 4 4 0 Domain of unknown function (DUF2529) DicB PF05358.11 PSC73959.1 - 0.059 13.5 0.1 0.16 12.1 0.1 1.7 1 0 0 1 1 1 0 DicB protein Lactamase_B_6 PF16661.5 PSC73960.1 - 7.7e-57 191.8 0.0 1.3e-56 191.1 0.0 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 PSC73960.1 - 1.7e-23 83.0 0.0 5.5e-23 81.4 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain CPSF100_C PF13299.6 PSC73960.1 - 4.6e-20 72.5 0.8 7e-18 65.4 0.0 3.1 2 1 1 3 3 3 1 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.12 PSC73960.1 - 1.2e-12 47.5 0.0 3.7e-12 46.0 0.0 1.9 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 PSC73960.1 - 6.5e-12 45.9 0.0 1.7e-11 44.5 0.0 1.7 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PSC73960.1 - 3.1e-10 39.9 0.0 8.4e-10 38.5 0.0 1.7 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Acetyltransf_13 PF13880.6 PSC73961.1 - 1.1e-24 86.1 0.0 1.9e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 PSC73961.1 - 9.1e-16 57.4 0.4 1.6e-15 56.7 0.4 1.4 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO TFIIA PF03153.13 PSC73961.1 - 0.0029 17.7 23.8 0.0029 17.7 23.8 2.1 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Endostatin PF06482.11 PSC73961.1 - 0.0086 15.6 0.5 0.0086 15.6 0.5 1.5 2 0 0 2 2 2 1 Collagenase NC10 and Endostatin Acetyltransf_7 PF13508.7 PSC73961.1 - 0.018 15.4 0.0 0.071 13.5 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Glypican PF01153.19 PSC73961.1 - 0.52 9.1 4.7 0.81 8.4 4.7 1.2 1 0 0 1 1 1 0 Glypican Neur_chan_memb PF02932.16 PSC73961.1 - 0.66 10.0 2.3 1.1 9.2 2.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Eapp_C PF10238.9 PSC73961.1 - 4.4 7.4 12.1 8.5 6.4 0.1 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Presenilin PF01080.17 PSC73961.1 - 4.9 5.8 12.5 9.7 4.8 12.5 1.4 1 0 0 1 1 1 0 Presenilin DUF3402 PF11882.8 PSC73961.1 - 8.4 5.4 8.8 13 4.7 8.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3402) Glutaredoxin PF00462.24 PSC73962.1 - 5.6e-19 68.1 0.0 2.2e-18 66.2 0.1 2.1 2 0 0 2 2 2 1 Glutaredoxin DUF775 PF05603.12 PSC73962.1 - 4.7e-18 65.5 0.0 2.5e-16 59.8 0.0 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF775) LIAS_N PF16881.5 PSC73962.1 - 0.0034 17.8 0.0 0.12 12.9 0.0 3.0 2 1 1 3 3 3 1 N-terminal domain of lipoyl synthase of Radical_SAM family GST_N_3 PF13417.6 PSC73962.1 - 0.014 15.8 0.0 0.07 13.5 0.0 2.1 1 1 1 2 2 2 0 Glutathione S-transferase, N-terminal domain XPA_C PF05181.12 PSC73962.1 - 0.019 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 XPA protein C-terminus Glutaredoxin PF00462.24 PSC73963.1 - 5.4e-19 68.2 0.0 2.1e-18 66.3 0.1 2.1 2 0 0 2 2 2 1 Glutaredoxin DUF775 PF05603.12 PSC73963.1 - 8.6e-13 48.3 0.0 5.6e-07 29.3 0.0 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF775) LIAS_N PF16881.5 PSC73963.1 - 0.0033 17.8 0.0 0.11 12.9 0.0 3.0 2 1 1 3 3 3 1 N-terminal domain of lipoyl synthase of Radical_SAM family GST_N_3 PF13417.6 PSC73963.1 - 0.013 15.8 0.0 0.065 13.6 0.0 2.1 1 1 1 2 2 2 0 Glutathione S-transferase, N-terminal domain XPA_C PF05181.12 PSC73963.1 - 0.019 14.9 0.0 0.037 14.0 0.0 1.4 1 0 0 1 1 1 0 XPA protein C-terminus Peptidase_M50 PF02163.22 PSC73964.1 - 5.9e-07 29.0 8.2 0.0053 16.0 0.2 2.9 1 1 1 2 2 2 2 Peptidase family M50 Peptidase_M50B PF13398.6 PSC73964.1 - 0.00043 20.0 5.8 0.00043 20.0 5.8 2.3 3 0 0 3 3 3 1 Peptidase M50B-like DUF3267 PF11667.8 PSC73964.1 - 0.003 17.8 2.3 0.011 16.1 2.3 2.0 1 1 0 1 1 1 1 Putative zincin peptidase PNPase_C PF12111.8 PSC73964.1 - 0.009 15.4 1.0 0.009 15.4 1.0 1.9 2 0 0 2 2 2 1 Polyribonucleotide phosphorylase C terminal DUF2892 PF11127.8 PSC73964.1 - 0.046 13.8 1.7 0.046 13.8 1.7 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF2892) Mito_fiss_reg PF05308.11 PSC73967.1 - 3.5 7.6 7.0 5.1 7.1 7.0 1.4 1 0 0 1 1 1 0 Mitochondrial fission regulator PTR2 PF00854.21 PSC73968.1 - 5.6e-102 341.5 0.9 5.6e-102 341.5 0.9 1.3 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 PSC73968.1 - 2.4e-10 39.9 26.6 4.9e-09 35.6 20.0 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily bZIP_1 PF00170.21 PSC73969.1 - 1.4e-06 28.3 10.1 2.2e-06 27.7 10.0 1.5 1 1 0 1 1 1 1 bZIP transcription factor DUF641 PF04859.12 PSC73969.1 - 0.046 14.1 1.0 0.069 13.5 1.0 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) bZIP_Maf PF03131.17 PSC73969.1 - 0.066 13.7 8.6 0.12 12.9 8.6 1.4 1 1 0 1 1 1 0 bZIP Maf transcription factor bZIP_2 PF07716.15 PSC73969.1 - 0.23 11.5 16.3 0.3 11.2 12.7 2.1 1 1 1 2 2 2 0 Basic region leucine zipper Radical_SAM PF04055.21 PSC73970.1 - 2.2e-13 50.9 0.0 4.4e-13 50.0 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily B12-binding PF02310.19 PSC73970.1 - 0.0014 18.7 0.0 0.017 15.2 0.0 2.4 2 0 0 2 2 2 1 B12 binding domain RRM_1 PF00076.22 PSC73971.1 - 3.1e-20 71.8 0.0 6.3e-12 45.1 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PSC73971.1 - 5.1e-07 29.7 0.0 0.0026 17.9 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 PSC73971.1 - 0.075 12.9 0.0 1.5 8.7 0.0 2.4 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF966 PF06136.13 PSC73971.1 - 0.7 9.6 16.1 1.4 8.6 16.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Macoilin PF09726.9 PSC73971.1 - 2.6 6.5 14.3 3.8 5.9 14.3 1.2 1 0 0 1 1 1 0 Macoilin family Ion_trans PF00520.31 PSC73972.1 - 6.8e-10 38.6 2.8 9.9e-10 38.1 2.8 1.1 1 0 0 1 1 1 1 Ion transport protein DUF4491 PF14898.6 PSC73972.1 - 10 6.7 7.2 26 5.3 3.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4491) Lipase_GDSL_2 PF13472.6 PSC73973.1 - 1.2e-10 42.1 0.0 1.5e-10 41.8 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 PSC73973.1 - 0.0013 18.7 0.0 0.0018 18.3 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase OSK PF17182.4 PSC73973.1 - 0.19 10.9 0.0 0.23 10.7 0.0 1.1 1 0 0 1 1 1 0 OSK domain RSN1_7TM PF02714.15 PSC73974.1 - 7.2e-66 222.3 24.0 1.2e-65 221.5 24.0 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 PSC73974.1 - 1.5e-32 112.5 16.4 2.3e-27 95.7 0.1 4.1 4 1 2 6 6 6 2 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 PSC73974.1 - 1.6e-16 61.1 0.1 3.3e-16 60.0 0.0 1.5 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter RSN1_7TM PF02714.15 PSC73975.1 - 7e-66 222.3 24.0 1.2e-65 221.5 24.0 1.4 1 0 0 1 1 1 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 PSC73975.1 - 1.5e-32 112.5 3.2 2.3e-27 95.7 0.1 4.1 4 1 2 6 6 6 2 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 PSC73975.1 - 1.5e-16 61.1 0.1 3.3e-16 60.0 0.0 1.5 2 0 0 2 2 2 1 Cytosolic domain of 10TM putative phosphate transporter Rotamase_3 PF13616.6 PSC73976.1 - 2.9e-16 60.0 0.0 5.1e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase PF00639.21 PSC73976.1 - 2.9e-15 57.0 0.0 5e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rhodanese PF00581.20 PSC73976.1 - 8.8e-08 32.6 0.0 5.7e-07 30.0 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain C2 PF00168.30 PSC73977.1 - 5.4e-20 71.6 0.0 1.1e-12 48.1 0.0 2.5 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 PSC73977.1 - 2.8e-07 30.2 0.0 4.9e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain CTNNBL PF08216.11 PSC73978.1 - 2.3e-31 108.1 0.6 6.4e-31 106.6 0.1 2.0 2 0 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear E3_UbLigase_R4 PF13764.6 PSC73978.1 - 0.00015 20.1 4.2 0.028 12.6 0.1 2.3 1 1 1 2 2 2 2 E3 ubiquitin-protein ligase UBR4 V-ATPase_H_N PF03224.14 PSC73978.1 - 0.0025 17.2 4.4 0.005 16.2 0.4 2.6 1 1 1 2 2 2 1 V-ATPase subunit H Arm PF00514.23 PSC73978.1 - 0.0031 17.5 2.4 0.22 11.6 0.2 3.9 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 PSC73978.1 - 0.054 13.5 4.0 0.19 11.8 2.4 2.3 1 1 1 2 2 2 0 non-SMC mitotic condensation complex subunit 1 DUF3361 PF11841.8 PSC73978.1 - 0.055 13.4 4.0 0.84 9.6 0.2 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3361) LemA PF04011.12 PSC73978.1 - 0.078 12.8 2.2 0.13 12.1 0.4 2.2 2 0 0 2 2 2 0 LemA family PrmC_N PF17827.1 PSC73978.1 - 0.27 11.8 8.8 0.15 12.6 1.6 3.4 3 0 0 3 3 3 0 PrmC N-terminal domain SET PF00856.28 PSC73979.1 - 6.8e-20 72.1 1.0 5.9e-19 69.1 0.0 2.9 2 1 0 2 2 2 1 SET domain AWS PF17907.1 PSC73979.1 - 3.5e-15 55.8 3.5 7.2e-15 54.7 3.5 1.6 1 0 0 1 1 1 1 AWS domain zf-CW PF07496.15 PSC73979.1 - 1.2e-13 50.9 4.5 2.3e-13 49.9 4.5 1.5 1 0 0 1 1 1 1 CW-type Zinc Finger BSP_II PF05432.11 PSC73979.1 - 1.4 8.6 5.9 2.4 7.8 5.9 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FAD_binding_4 PF01565.23 PSC73980.1 - 2.8e-27 95.2 3.0 6.2e-27 94.0 3.0 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 PSC73980.1 - 1.7e-07 31.3 0.0 3.5e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Berberine and berberine like TFIIA PF03153.13 PSC73980.1 - 0.0038 17.3 5.0 0.0059 16.7 5.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4834 PF16118.5 PSC73980.1 - 0.041 14.8 0.3 0.075 14.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) SUIM_assoc PF16619.5 PSC73980.1 - 0.051 13.7 11.0 0.16 12.0 11.0 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 PSC73980.1 - 0.16 11.5 14.4 0.25 10.9 14.4 1.1 1 0 0 1 1 1 0 Spt20 family RAB3GAP2_N PF14655.6 PSC73980.1 - 0.46 9.7 2.6 0.78 8.9 2.6 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF2722 PF10846.8 PSC73980.1 - 0.96 8.3 10.9 1.4 7.8 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.8 PSC73980.1 - 1.4 7.8 19.9 2.2 7.2 19.9 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF3309 PF11752.8 PSC73981.1 - 0.42 10.7 0.9 0.65 10.1 0.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) Glyco_transf_20 PF00982.21 PSC73982.1 - 4e-180 599.6 0.0 4.8e-180 599.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 PSC73982.1 - 7.2e-40 136.6 0.0 2.5e-39 134.8 0.0 1.7 2 0 0 2 2 2 1 Trehalose-phosphatase Glyco_trans_1_2 PF13524.6 PSC73982.1 - 0.0018 18.6 0.1 0.0051 17.2 0.1 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.20 PSC73982.1 - 0.0051 16.4 0.0 0.067 12.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PSC73982.1 - 0.018 15.4 0.0 0.064 13.7 0.0 2.0 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 PSC73982.1 - 0.074 12.7 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Starch synthase catalytic domain RskA PF10099.9 PSC73982.1 - 0.84 9.9 21.6 2.5 8.4 5.1 2.5 2 0 0 2 2 2 0 Anti-sigma-K factor rskA DUF1180 PF06679.12 PSC73982.1 - 1.7 9.0 4.3 3.8 7.9 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) LMBR1 PF04791.16 PSC73983.1 - 1.3e-68 232.1 0.0 1.9e-68 231.6 0.0 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein BSP_II PF05432.11 PSC73983.1 - 0.13 11.9 6.4 0.19 11.4 6.4 1.1 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Pex14_N PF04695.13 PSC73983.1 - 0.52 11.0 9.7 1.2 9.8 9.7 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4551 PF15087.6 PSC73983.1 - 0.58 8.9 5.3 0.83 8.4 5.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CPSF100_C PF13299.6 PSC73983.1 - 0.93 9.6 4.2 1.7 8.8 4.2 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Coilin_N PF15862.5 PSC73983.1 - 5.3 6.8 5.4 8.3 6.2 5.4 1.2 1 0 0 1 1 1 0 Coilin N-terminus GTP_EFTU PF00009.27 PSC73984.1 - 7e-41 139.9 0.0 1.3e-40 139.1 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 PSC73984.1 - 1.4e-35 122.5 10.2 2.8e-35 121.5 10.2 1.5 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_C PF00679.24 PSC73984.1 - 2.9e-23 81.7 0.0 8.8e-23 80.2 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_IV PF03764.18 PSC73984.1 - 3.3e-23 81.8 0.0 8.8e-23 80.4 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV GTP_EFTU_D2 PF03144.25 PSC73984.1 - 1.6e-12 47.6 0.0 4.9e-12 46.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 PSC73984.1 - 2.4e-05 24.3 0.0 5.1e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 PSC73984.1 - 0.015 15.4 0.0 0.031 14.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Hydrolase_4 PF12146.8 PSC73985.1 - 6.1e-15 55.1 0.3 1.8e-11 43.8 0.1 2.1 1 1 0 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PSC73985.1 - 2.2e-12 47.2 0.1 6.9e-11 42.3 0.1 2.0 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PSC73985.1 - 2.4e-12 47.9 8.6 4.3e-12 47.1 8.6 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 PSC73985.1 - 1.7e-07 30.9 0.0 6.4e-07 29.1 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family UPF0227 PF05728.12 PSC73985.1 - 5.3e-07 29.8 0.1 7.7e-07 29.2 0.1 1.5 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0227) Esterase PF00756.20 PSC73985.1 - 1.7e-06 27.9 0.1 2.2e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Putative esterase Ser_hydrolase PF06821.13 PSC73985.1 - 3e-06 27.2 0.1 5.9e-06 26.3 0.1 1.5 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_2 PF02230.16 PSC73985.1 - 5.8e-05 23.0 0.0 0.054 13.3 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.13 PSC73985.1 - 0.0018 18.1 0.1 0.003 17.4 0.1 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2920 PF11144.8 PSC73985.1 - 0.0061 15.8 0.0 0.044 12.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2920) Methyltransf_19 PF04672.12 PSC73985.1 - 0.027 14.0 0.1 0.07 12.6 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl methyltransferase DLH PF01738.18 PSC73985.1 - 0.06 12.9 0.0 0.65 9.5 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family Spt20 PF12090.8 PSC73986.1 - 3.1 7.4 4.9 5.1 6.6 4.9 1.2 1 0 0 1 1 1 0 Spt20 family Spt20 PF12090.8 PSC73987.1 - 3.1 7.4 4.9 5.1 6.6 4.9 1.2 1 0 0 1 1 1 0 Spt20 family UDPG_MGDP_dh_N PF03721.14 PSC73988.1 - 4.9e-65 218.6 0.4 9.3e-65 217.7 0.4 1.4 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 PSC73988.1 - 1.1e-34 119.0 0.0 3.4e-34 117.4 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 PSC73988.1 - 3.3e-32 110.5 0.1 7.5e-32 109.4 0.1 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 PSC73988.1 - 0.00076 19.7 0.0 0.0082 16.3 0.1 2.5 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 PSC73988.1 - 0.0054 17.0 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 PSC73988.1 - 0.0079 16.1 0.4 0.061 13.2 0.0 2.5 3 0 0 3 3 3 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ApbA PF02558.16 PSC73988.1 - 0.018 14.7 0.0 0.06 13.0 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.22 PSC73988.1 - 0.041 14.7 0.5 0.19 12.6 0.1 2.2 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Ldh_1_N PF00056.23 PSC73988.1 - 0.058 13.5 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Pkinase PF00069.25 PSC73989.1 - 1.2e-73 247.7 0.0 1.5e-73 247.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC73989.1 - 6.1e-34 117.5 0.0 8.2e-34 117.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC73989.1 - 1.9e-08 34.0 0.0 3.1e-05 23.5 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.14 PSC73989.1 - 4.1e-08 32.8 0.0 6.2e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PSC73989.1 - 0.00012 21.2 0.0 0.00016 20.7 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 PSC73989.1 - 0.00012 21.7 0.1 0.00021 20.9 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 PSC73989.1 - 0.00023 20.1 0.0 0.00034 19.5 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase DUF4861 PF16153.5 PSC73989.1 - 0.085 11.8 0.1 0.13 11.2 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4861) Phytochelatin PF05023.14 PSC73990.1 - 3.2e-87 291.2 0.0 5.1e-87 290.5 0.0 1.3 1 0 0 1 1 1 1 Phytochelatin synthase Phytochelatin_C PF09328.10 PSC73990.1 - 3.7e-05 23.2 0.4 0.15 11.4 0.1 2.9 3 1 0 3 3 3 2 Domain of unknown function (DUF1984) Peptidase_C39_2 PF13529.6 PSC73990.1 - 0.0061 17.1 0.0 0.17 12.5 0.0 2.4 2 0 0 2 2 2 1 Peptidase_C39 like family CTU2 PF10288.9 PSC73990.1 - 0.014 15.7 6.4 0.014 15.7 6.4 2.5 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 TFIIA PF03153.13 PSC73990.1 - 0.025 14.6 47.9 0.14 12.1 16.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DCA16 PF15349.6 PSC73990.1 - 0.063 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 DDB1- and CUL4-associated factor 16 DDHD PF02862.17 PSC73990.1 - 0.74 9.9 9.9 3.3 7.8 4.1 2.3 2 0 0 2 2 2 0 DDHD domain DUF3408 PF11888.8 PSC73990.1 - 1.8 8.7 24.9 2.1 8.5 10.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) DUF3807 PF12720.7 PSC73990.1 - 2.3 8.5 23.0 1.6 8.9 3.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Glyco_hydro_47 PF01532.20 PSC73991.1 - 9.8e-153 509.3 0.2 1.3e-152 508.9 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Furin-like PF00757.20 PSC73993.1 - 2 8.3 13.6 0.11 12.3 5.4 2.5 2 0 0 2 2 2 0 Furin-like cysteine rich region C2-C2_1 PF11618.8 PSC73994.1 - 0.043 13.9 0.1 0.062 13.4 0.1 1.2 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 tRNA_bind PF01588.20 PSC73995.1 - 0.0082 16.2 0.0 1.5 8.9 0.0 3.3 3 0 0 3 3 3 1 Putative tRNA binding domain XPA_C PF05181.12 PSC73995.1 - 0.011 15.7 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 XPA protein C-terminus BEX PF04538.12 PSC73995.1 - 5.5 7.6 10.9 1.1 9.9 3.9 3.2 3 0 0 3 3 3 0 Brain expressed X-linked like family Acyltransferase PF01553.21 PSC73996.1 - 2.7e-15 56.2 0.0 7.1e-15 54.8 0.0 1.8 1 0 0 1 1 1 1 Acyltransferase Heme_oxygenase PF01126.20 PSC73997.1 - 1e-38 133.2 0.1 1.2e-38 133.0 0.1 1.0 1 0 0 1 1 1 1 Heme oxygenase Ammonium_transp PF00909.21 PSC73998.1 - 1.4e-108 363.1 27.9 1.4e-108 363.1 27.9 1.8 2 0 0 2 2 2 1 Ammonium Transporter Family DUF3754 PF12576.8 PSC73998.1 - 1.3e-21 77.0 0.1 4.2e-21 75.3 0.1 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3754) SIS PF01380.22 PSC73999.1 - 2.4e-48 163.3 1.4 4e-28 97.9 0.2 2.6 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 PSC73999.1 - 2.3e-15 57.0 0.0 5.8e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pkinase PF00069.25 PSC73999.1 - 7.4e-14 51.7 0.0 1.2e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain GATase_7 PF13537.6 PSC73999.1 - 1.2e-11 44.6 0.0 2.5e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.6 PSC73999.1 - 0.00024 20.1 0.0 0.00047 19.2 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Pkinase_Tyr PF07714.17 PSC73999.1 - 0.00068 19.0 0.0 0.0014 18.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase SIS_2 PF13580.6 PSC73999.1 - 0.0019 18.2 0.1 0.17 11.9 0.0 3.3 2 1 1 3 3 3 1 SIS domain DUF2529 PF10740.9 PSC73999.1 - 0.11 12.1 0.0 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF2529) DEAD PF00270.29 PSC74000.1 - 1.7e-47 161.5 0.0 4e-47 160.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC74000.1 - 7.4e-30 103.6 0.0 2.6e-28 98.6 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain UTP25 PF06862.12 PSC74000.1 - 0.00036 19.4 0.0 0.024 13.4 0.0 2.3 2 1 0 2 2 2 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 ERCC3_RAD25_C PF16203.5 PSC74000.1 - 0.0013 18.0 0.0 0.0022 17.3 0.0 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 PSC74000.1 - 0.0016 18.5 0.0 0.0054 16.7 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Wbp11 PF09429.10 PSC74000.1 - 0.0065 16.9 1.8 0.0065 16.9 1.8 2.4 2 0 0 2 2 2 1 WW domain binding protein 11 CMS1 PF14617.6 PSC74000.1 - 0.023 14.0 0.0 0.063 12.6 0.0 1.8 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit DUF3138 PF11336.8 PSC74000.1 - 7.8 5.0 7.5 12 4.4 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Cpn60_TCP1 PF00118.24 PSC74001.1 - 5.9e-90 302.2 14.4 8.5e-90 301.7 14.4 1.2 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DNA_pol_A_exo1 PF01612.20 PSC74001.1 - 1e-15 57.9 0.0 2.5e-15 56.6 0.0 1.6 1 0 0 1 1 1 1 3'-5' exonuclease EF-hand_6 PF13405.6 PSC74001.1 - 3.3e-06 26.6 1.5 0.001 18.8 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 PSC74001.1 - 7.3e-06 25.2 0.0 1.8e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 EF hand EF-hand_1 PF00036.32 PSC74001.1 - 9.5e-06 24.8 0.1 0.00041 19.7 0.0 2.5 2 0 0 2 2 2 1 EF hand F-box-like PF12937.7 PSC74001.1 - 2.8e-05 23.9 0.1 6.7e-05 22.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like EF-hand_8 PF13833.6 PSC74001.1 - 0.00028 20.7 0.0 0.0013 18.6 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_7 PF13499.6 PSC74001.1 - 0.00028 21.3 0.4 0.00064 20.1 0.4 1.6 1 0 0 1 1 1 1 EF-hand domain pair F-box PF00646.33 PSC74001.1 - 0.018 14.9 0.0 0.044 13.7 0.0 1.7 1 0 0 1 1 1 0 F-box domain LRR_8 PF13855.6 PSC74001.1 - 0.098 12.4 0.0 0.56 10.0 0.0 2.5 1 0 0 1 1 1 0 Leucine rich repeat Exo_endo_phos PF03372.23 PSC74002.1 - 9.8e-14 51.4 6.9 1e-12 48.1 6.9 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DNA_topoisoIV PF00521.20 PSC74003.1 - 5.8e-140 466.9 0.0 7.3e-140 466.6 0.0 1.1 1 0 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseA_C PF03989.13 PSC74003.1 - 5.4e-57 189.1 8.4 7.9e-11 41.3 0.0 6.5 6 0 0 6 6 6 6 DNA gyrase C-terminal domain, beta-propeller Hydrolase PF00702.26 PSC74005.1 - 3.9e-17 63.3 10.6 3.7e-12 47.0 1.2 2.9 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 PSC74005.1 - 0.016 15.0 0.4 0.024 14.4 0.4 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Lipase_3 PF01764.25 PSC74006.1 - 6.4e-07 29.3 0.0 5.4e-05 23.1 0.0 2.3 2 0 0 2 2 2 2 Lipase (class 3) Thioesterase PF00975.20 PSC74006.1 - 8.3e-05 22.8 0.1 0.00015 21.9 0.1 1.4 1 0 0 1 1 1 1 Thioesterase domain DUF2974 PF11187.8 PSC74006.1 - 0.17 11.4 0.1 0.27 10.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) MACPF PF01823.19 PSC74007.1 - 1.7e-13 51.2 0.8 2.5e-13 50.6 0.1 1.6 2 0 0 2 2 2 1 MAC/Perforin domain CDH PF02611.15 PSC74007.1 - 0.00036 20.2 0.0 0.00093 18.9 0.0 1.6 1 1 1 2 2 2 1 CDP-diacylglycerol pyrophosphatase OTT_1508_deam PF14441.6 PSC74007.1 - 2.1 8.4 5.4 37 4.4 0.1 2.5 2 0 0 2 2 2 0 OTT_1508-like deaminase Methyltrn_RNA_3 PF02598.17 PSC74008.1 - 5.3e-92 308.4 0.0 6.1e-92 308.2 0.0 1.0 1 0 0 1 1 1 1 Putative RNA methyltransferase SpoU_methylase PF00588.19 PSC74008.1 - 0.016 15.4 0.0 0.099 12.8 0.0 2.1 2 0 0 2 2 2 0 SpoU rRNA Methylase family Hist_deacetyl PF00850.19 PSC74011.1 - 2.7e-45 155.2 0.0 4.2e-45 154.6 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain EF-hand_1 PF00036.32 PSC74012.1 - 1.5e-06 27.3 0.0 1.5e-05 24.2 0.0 2.3 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 PSC74012.1 - 2.8e-06 26.6 0.0 7.6e-06 25.2 0.0 1.8 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 PSC74012.1 - 2e-05 24.1 0.1 9.9e-05 22.0 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 PSC74012.1 - 7.1e-05 23.2 0.0 0.00023 21.5 0.0 1.8 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_8 PF13833.6 PSC74012.1 - 0.00079 19.2 0.0 0.0019 18.0 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain pair ABATE PF07336.11 PSC74012.1 - 0.012 16.3 5.9 0.023 15.4 5.9 1.4 1 0 0 1 1 1 0 Putative stress-induced transcription regulator Nucleotid_trans PF03407.16 PSC74013.1 - 1.4e-21 77.5 0.0 6.4e-21 75.3 0.0 1.9 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DNA_photolyase PF00875.18 PSC74013.1 - 3.7e-09 36.8 0.7 1.7e-08 34.6 0.2 2.5 2 0 0 2 2 2 1 DNA photolyase XPA_C PF05181.12 PSC74013.1 - 2.7e-08 33.7 0.0 5.2e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 XPA protein C-terminus FAD_binding_7 PF03441.14 PSC74013.1 - 3.6e-05 23.3 0.2 7.8e-05 22.2 0.2 1.6 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase Tyr-DNA_phospho PF06087.12 PSC74013.1 - 0.05 12.5 0.1 0.084 11.8 0.1 1.3 1 0 0 1 1 1 0 Tyrosyl-DNA phosphodiesterase CDC45 PF02724.14 PSC74013.1 - 2.2 6.4 5.6 3.4 5.8 5.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Paf1 PF03985.13 PSC74013.1 - 7.2 5.5 18.4 12 4.8 18.4 1.2 1 0 0 1 1 1 0 Paf1 GDA1_CD39 PF01150.17 PSC74014.1 - 5.8e-57 193.2 0.0 8.2e-57 192.7 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ribonuclease_T2 PF00445.18 PSC74014.1 - 4.3e-15 56.4 0.0 1.2e-14 55.0 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease T2 family Trypan_PARP PF05887.11 PSC74015.1 - 0.55 10.2 15.8 0.12 12.4 7.9 2.2 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) GDA1_CD39 PF01150.17 PSC74016.1 - 6.3e-87 292.0 0.0 8.9e-87 291.5 0.0 1.1 1 0 0 1 1 1 1 GDA1/CD39 (nucleoside phosphatase) family Ribonuclease_T2 PF00445.18 PSC74016.1 - 5.3e-15 56.1 0.0 8.6e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease T2 family DUF1505 PF07403.11 PSC74016.1 - 0.57 10.4 2.6 1.3 9.2 0.2 2.7 3 1 0 3 3 3 0 Protein of unknown function (DUF1505) Aminotran_1_2 PF00155.21 PSC74017.1 - 6.6e-56 190.0 0.0 7.9e-56 189.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Alliinase_C PF04864.13 PSC74017.1 - 0.0019 17.1 0.0 0.0032 16.4 0.0 1.3 1 0 0 1 1 1 1 Allinase Cys_Met_Meta_PP PF01053.20 PSC74017.1 - 0.005 15.4 0.0 0.042 12.4 0.0 1.9 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme L51_S25_CI-B8 PF05047.16 PSC74017.1 - 0.18 11.8 0.0 2 8.4 0.0 2.2 2 0 0 2 2 2 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Peptidase_C1 PF00112.23 PSC74018.1 - 2.4e-51 174.9 0.0 3.7e-51 174.3 0.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PSC74018.1 - 2.1e-12 47.3 1.4 3.1e-12 46.7 1.4 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PSC74018.1 - 0.00041 19.2 0.4 0.067 12.0 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Cohesin_load PF10345.9 PSC74019.1 - 0.00046 18.8 0.0 0.82 8.0 0.0 2.6 3 0 0 3 3 3 2 Cohesin loading factor YfdX PF10938.8 PSC74019.1 - 0.21 11.5 0.0 0.21 11.5 0.0 4.7 6 1 0 6 6 6 0 YfdX protein TPR_12 PF13424.6 PSC74019.1 - 1.8 8.9 36.4 0.72 10.2 2.1 7.3 6 3 1 8 8 8 0 Tetratricopeptide repeat TPR_10 PF13374.6 PSC74019.1 - 3 7.8 9.1 16 5.6 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat Polysacc_deac_1 PF01522.21 PSC74020.1 - 3.4e-12 46.3 0.1 6.3e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase zf-4CXXC_R1 PF10497.9 PSC74023.1 - 2.4e-32 111.1 16.2 4.6e-32 110.2 16.2 1.5 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 DUF4242 PF14026.6 PSC74023.1 - 9.3e-22 77.0 0.0 3.3e-21 75.2 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4242) MATH PF00917.26 PSC74023.1 - 2.7e-06 27.5 0.0 4.5e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 MATH domain BTB PF00651.31 PSC74023.1 - 0.06 13.6 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain ORF_12_N PF18042.1 PSC74023.1 - 0.064 13.7 0.2 0.61 10.5 0.0 2.8 3 0 0 3 3 3 0 ORF 12 gene product N-terminal Methyltransf_11 PF08241.12 PSC74024.1 - 2.3e-07 31.4 0.0 1.7e-06 28.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC74024.1 - 5e-06 27.1 0.0 1.9e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC74024.1 - 0.00019 22.1 0.0 0.00062 20.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC74024.1 - 0.027 14.3 0.0 0.066 13.0 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MetW PF07021.12 PSC74024.1 - 0.06 12.9 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Ubie_methyltran PF01209.18 PSC74024.1 - 0.26 10.6 0.2 3.4 7.0 0.0 2.2 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family rve PF00665.26 PSC74026.1 - 1.1e-18 67.5 0.0 2.2e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC74026.1 - 0.0088 15.8 0.0 0.025 14.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Ycf54 PF10674.9 PSC74027.1 - 1.8e-17 63.4 0.1 2.8e-17 62.8 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2488) UCH PF00443.29 PSC74028.1 - 9e-40 136.8 0.0 1.6e-39 136.0 0.0 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 PSC74028.1 - 3.6e-19 68.3 0.1 8.6e-19 67.1 0.1 1.7 1 0 0 1 1 1 1 Variant UBP zinc finger UBA PF00627.31 PSC74028.1 - 1.7e-17 63.0 0.0 1.1e-08 34.8 0.0 2.6 2 0 0 2 2 2 2 UBA/TS-N domain UCH_1 PF13423.6 PSC74028.1 - 3.3e-14 53.2 0.0 1.1e-08 35.1 0.0 2.7 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 PSC74028.1 - 7.9e-09 35.7 0.0 2.9e-08 33.9 0.0 1.9 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein 2-Hacid_dh_C PF02826.19 PSC74029.1 - 8.2e-37 126.3 0.6 1.3e-26 93.0 0.0 2.6 3 0 0 3 3 3 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PSC74029.1 - 2.6e-18 66.0 0.0 3.2e-18 65.7 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_7 PF13241.6 PSC74029.1 - 0.0087 16.5 0.0 0.016 15.6 0.0 1.4 1 0 0 1 1 1 1 Putative NAD(P)-binding Pyr_redox_2 PF07992.14 PSC74029.1 - 0.042 13.1 0.0 0.26 10.5 0.0 2.0 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase MFS_1 PF07690.16 PSC74030.1 - 4e-15 55.6 58.3 2.3e-12 46.5 44.1 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Lipoprotein_2 PF00921.17 PSC74030.1 - 9.8 5.6 8.4 15 5.0 8.4 1.1 1 0 0 1 1 1 0 Borrelia lipoprotein MFS_1 PF07690.16 PSC74031.1 - 4.3e-15 55.5 58.5 4.6e-12 45.5 44.8 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Lipoprotein_2 PF00921.17 PSC74031.1 - 9.8 5.6 8.4 15 5.1 8.4 1.1 1 0 0 1 1 1 0 Borrelia lipoprotein DHHC PF01529.20 PSC74032.1 - 3e-23 82.4 9.8 8.9e-23 80.9 9.8 1.8 1 0 0 1 1 1 1 DHHC palmitoyltransferase TAFII55_N PF04658.13 PSC74032.1 - 3.6e-14 52.8 0.0 7e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 TAFII55 protein conserved region DHHC PF01529.20 PSC74033.1 - 3.3e-23 82.3 9.8 9.5e-23 80.8 9.8 1.8 1 0 0 1 1 1 1 DHHC palmitoyltransferase TAFII55_N PF04658.13 PSC74033.1 - 3.9e-14 52.7 0.0 7.5e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 TAFII55 protein conserved region DUF3783 PF12646.7 PSC74033.1 - 0.068 13.1 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3783) Mcm10 PF09332.11 PSC74034.1 - 1.2 8.5 26.0 3 7.2 7.7 2.3 2 0 0 2 2 2 0 Mcm10 replication factor SAPS PF04499.15 PSC74034.1 - 7.5 5.2 7.8 13 4.4 7.8 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Prenyltrans PF00432.21 PSC74035.1 - 8.5e-61 201.4 27.7 2.9e-13 49.3 2.2 6.2 6 0 0 6 6 6 6 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_N PF13249.6 PSC74035.1 - 2e-05 23.8 0.0 0.016 14.3 0.0 3.4 2 2 1 3 3 3 1 Squalene-hopene cyclase N-terminal domain Coilin_N PF15862.5 PSC74035.1 - 0.039 13.8 1.1 0.06 13.2 1.1 1.4 1 0 0 1 1 1 0 Coilin N-terminus bZIP_Maf PF03131.17 PSC74035.1 - 0.15 12.6 18.2 0.23 12.0 18.2 1.2 1 0 0 1 1 1 0 bZIP Maf transcription factor CCDC53 PF10152.9 PSC74035.1 - 2.5 8.5 9.5 3.5 8.0 9.5 1.2 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Roughex PF06020.11 PSC74035.1 - 9 5.3 7.8 12 4.9 7.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Ribonuc_red_sm PF00268.21 PSC74036.1 - 8.2e-119 396.2 0.5 9.6e-119 396.0 0.5 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain NMT PF01233.19 PSC74036.1 - 0.078 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain bZIP_1 PF00170.21 PSC74037.1 - 0.0014 18.6 15.0 0.0047 17.0 13.7 2.2 2 0 0 2 2 2 1 bZIP transcription factor DUF5476 PF17570.2 PSC74037.1 - 0.04 14.3 0.0 0.1 13.0 0.0 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5476) bZIP_2 PF07716.15 PSC74037.1 - 0.074 13.2 19.0 0.32 11.1 19.0 2.1 1 1 0 1 1 1 0 Basic region leucine zipper Death PF00531.22 PSC74037.1 - 0.1 12.8 2.2 14 5.9 0.1 2.9 3 0 0 3 3 3 0 Death domain bZIP_Maf PF03131.17 PSC74037.1 - 9.4 6.8 18.1 0.47 11.0 10.0 2.7 3 1 0 3 3 3 0 bZIP Maf transcription factor PRKG1_interact PF15898.5 PSC74037.1 - 9.9 7.1 13.5 6.5 7.7 8.5 2.5 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain EamA PF00892.20 PSC74038.1 - 4.3e-05 23.7 24.9 0.073 13.2 0.6 3.5 3 0 0 3 3 3 3 EamA-like transporter family DDHD PF02862.17 PSC74038.1 - 0.59 10.3 4.1 0.45 10.6 1.5 2.1 2 0 0 2 2 2 0 DDHD domain RR_TM4-6 PF06459.12 PSC74038.1 - 5.7 6.7 7.8 8.7 6.1 7.8 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 PSC74038.1 - 5.9 3.9 7.1 7.8 3.5 7.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer TFIIA PF03153.13 PSC74038.1 - 6.3 6.7 27.6 10 6.0 27.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_M14 PF00246.24 PSC74040.1 - 1.4e-60 205.6 0.0 1.8e-60 205.2 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 PSC74040.1 - 3.7e-09 36.7 0.1 7.5e-09 35.7 0.1 1.5 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain AstE_AspA PF04952.14 PSC74040.1 - 1.9e-07 30.4 0.0 3.3e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family CarbopepD_reg_2 PF13715.6 PSC74040.1 - 0.0021 18.0 0.0 0.0039 17.2 0.0 1.3 1 0 0 1 1 1 1 CarboxypepD_reg-like domain PEGA PF08308.11 PSC74040.1 - 0.0047 16.8 0.0 0.0085 16.0 0.0 1.3 1 0 0 1 1 1 1 PEGA domain DUF2817 PF10994.8 PSC74040.1 - 0.0089 15.5 0.0 0.015 14.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) MlaD PF02470.20 PSC74041.1 - 1e-12 48.1 0.2 4e-12 46.2 0.0 2.0 2 0 0 2 2 2 1 MlaD protein DUF1664 PF07889.12 PSC74041.1 - 0.098 12.7 2.1 1 9.4 2.1 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) H-kinase_dim PF02895.14 PSC74041.1 - 0.18 12.2 2.1 0.29 11.6 0.5 2.2 2 0 0 2 2 2 0 Signal transducing histidine kinase, homodimeric domain Dscam_C PF12355.8 PSC74041.1 - 0.97 10.4 3.3 1 10.4 0.5 2.0 2 0 0 2 2 2 0 Down syndrome cell adhesion molecule C terminal CAP_N PF01213.19 PSC74041.1 - 1.1 8.7 6.3 0.12 11.8 1.3 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal DUF3138 PF11336.8 PSC74041.1 - 1.3 7.6 2.7 3.1 6.3 1.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) DnaJ PF00226.31 PSC74042.1 - 0.067 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 DnaJ domain Acetyltransf_1 PF00583.25 PSC74043.1 - 1.2e-09 38.4 0.0 1.5e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PSC74043.1 - 6.7e-08 32.5 0.0 9.1e-08 32.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PSC74043.1 - 2.6e-06 27.8 0.0 3.4e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC74043.1 - 9.2e-05 22.3 0.0 0.00014 21.8 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein DUF1330 PF07045.11 PSC74043.1 - 0.069 13.5 0.2 0.096 13.0 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1330) adh_short PF00106.25 PSC74044.1 - 1.2e-28 99.9 0.0 3.4e-28 98.4 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC74044.1 - 6.5e-16 58.6 0.0 1.7e-15 57.2 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC74044.1 - 7.5e-09 35.7 0.0 1.3e-08 34.9 0.0 1.4 1 0 0 1 1 1 1 KR domain RmlD_sub_bind PF04321.17 PSC74044.1 - 0.016 14.4 0.1 0.029 13.5 0.1 1.5 1 0 0 1 1 1 0 RmlD substrate binding domain Shikimate_DH PF01488.20 PSC74044.1 - 0.047 13.8 0.0 0.077 13.1 0.0 1.2 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.6 PSC74044.1 - 0.94 9.3 5.4 0.14 12.1 1.2 2.0 2 1 0 2 2 2 0 NAD(P)H-binding E1_dh PF00676.20 PSC74045.1 - 2.1e-75 253.5 0.0 2.8e-75 253.1 0.0 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component Glyco_hydro_18 PF00704.28 PSC74045.1 - 6.6e-73 246.2 0.2 9e-73 245.7 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 CBM_14 PF01607.24 PSC74045.1 - 1.5e-10 41.1 1.5 1.5e-10 41.1 1.5 2.4 2 0 0 2 2 2 1 Chitin binding Peritrophin-A domain TPP_enzyme_C PF02775.21 PSC74045.1 - 3.9e-07 30.0 0.2 8.6e-07 28.9 0.2 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain Chitin_bind_1 PF00187.19 PSC74045.1 - 0.0051 17.3 41.0 0.2 12.2 15.5 3.0 2 0 0 2 2 2 2 Chitin recognition protein DXP_synthase_N PF13292.6 PSC74045.1 - 0.0093 15.2 0.0 0.016 14.5 0.0 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Sugar_tr PF00083.24 PSC74046.1 - 9.9e-101 337.8 12.3 5.8e-99 332.0 7.2 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter adh_short_C2 PF13561.6 PSC74046.1 - 1.1e-47 162.5 0.6 2e-47 161.7 0.6 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PSC74046.1 - 2.8e-41 141.1 0.1 4.8e-41 140.4 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase MFS_1 PF07690.16 PSC74046.1 - 8.8e-24 84.1 18.8 8.8e-24 84.1 18.8 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily KR PF08659.10 PSC74046.1 - 3.6e-09 36.8 0.1 3.6e-09 36.8 0.1 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 PSC74046.1 - 0.16 11.4 0.2 0.29 10.6 0.2 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 PSC74046.1 - 0.16 11.1 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sugar_tr PF00083.24 PSC74047.1 - 1.5e-115 386.7 16.0 2e-115 386.3 16.0 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter adh_short_C2 PF13561.6 PSC74047.1 - 9.5e-47 159.5 0.9 1.8e-46 158.6 0.9 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PSC74047.1 - 1.5e-40 138.7 0.1 2.7e-40 137.9 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase MFS_1 PF07690.16 PSC74047.1 - 1.8e-23 83.1 20.1 1.8e-23 83.1 20.1 2.5 1 1 1 2 2 2 1 Major Facilitator Superfamily KR PF08659.10 PSC74047.1 - 3.9e-09 36.7 0.1 3.9e-09 36.7 0.1 1.8 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 PSC74047.1 - 0.095 12.2 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 PSC74047.1 - 0.17 11.0 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Sugar_tr PF00083.24 PSC74048.1 - 9.9e-101 337.8 12.3 5.8e-99 332.0 7.2 2.2 1 1 1 2 2 2 2 Sugar (and other) transporter adh_short_C2 PF13561.6 PSC74048.1 - 8.8e-47 159.6 0.9 1.7e-46 158.7 0.9 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PSC74048.1 - 1.4e-40 138.8 0.1 2.5e-40 138.0 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase MFS_1 PF07690.16 PSC74048.1 - 8.8e-24 84.1 18.8 8.8e-24 84.1 18.8 1.8 2 1 0 2 2 2 1 Major Facilitator Superfamily KR PF08659.10 PSC74048.1 - 3.7e-09 36.7 0.1 3.7e-09 36.7 0.1 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 PSC74048.1 - 0.088 12.3 0.1 0.15 11.5 0.1 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 PSC74048.1 - 0.16 11.1 0.0 0.23 10.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Pkinase PF00069.25 PSC74049.1 - 2e-58 197.8 0.0 3.1e-58 197.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74049.1 - 5.9e-23 81.5 0.0 9.5e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PSC74049.1 - 7.5e-06 25.0 0.0 0.00011 21.1 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase EF-hand_8 PF13833.6 PSC74049.1 - 4.9e-05 23.1 0.0 0.0011 18.8 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.6 PSC74049.1 - 0.005 17.3 0.1 0.032 14.7 0.0 2.4 3 0 0 3 3 3 1 EF-hand domain pair DUF2722 PF10846.8 PSC74049.1 - 0.012 14.6 8.0 0.016 14.2 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) APH PF01636.23 PSC74049.1 - 0.017 15.0 0.1 0.017 15.0 0.1 3.2 3 1 0 3 3 2 0 Phosphotransferase enzyme family Spt20 PF12090.8 PSC74049.1 - 0.024 14.3 13.8 0.039 13.6 13.8 1.3 1 0 0 1 1 1 0 Spt20 family TFIIA PF03153.13 PSC74049.1 - 0.031 14.3 16.7 0.049 13.6 16.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Seryl_tRNA_N PF02403.22 PSC74049.1 - 0.27 11.5 3.9 0.6 10.4 3.9 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Suf PF05843.14 PSC74049.1 - 0.45 10.4 5.6 0.83 9.6 5.6 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.13 PSC74049.1 - 0.51 11.0 14.1 2.5 8.8 14.2 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Roughex PF06020.11 PSC74049.1 - 2.1 7.3 5.2 3.3 6.7 5.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DHHC PF01529.20 PSC74050.1 - 2.6e-34 118.2 0.7 6.8e-34 116.9 0.7 1.5 1 1 0 1 1 1 1 DHHC palmitoyltransferase Ribosomal_L40e PF01020.17 PSC74050.1 - 0.027 14.4 7.7 0.052 13.4 7.7 1.4 1 0 0 1 1 1 0 Ribosomal L40e family DUF2427 PF10348.9 PSC74050.1 - 0.043 13.6 1.1 0.058 13.2 0.1 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) DUF3090 PF11290.8 PSC74050.1 - 0.18 11.6 1.5 9.9 5.9 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3090) Peptidase_M50 PF02163.22 PSC74051.1 - 0.00013 21.4 0.6 0.035 13.4 0.2 2.5 2 0 0 2 2 2 2 Peptidase family M50 DUF1690 PF07956.11 PSC74051.1 - 0.074 13.5 0.2 0.15 12.5 0.2 1.5 1 0 0 1 1 1 0 Protein of Unknown function (DUF1690) DUF1631 PF07793.11 PSC74051.1 - 0.45 8.9 4.0 0.66 8.3 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Tim17 PF02466.19 PSC74053.1 - 1.9e-17 63.6 9.4 3.8e-17 62.7 9.4 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family eRF1_1 PF03463.15 PSC74054.1 - 2.5e-46 156.9 0.0 3.6e-46 156.4 0.0 1.2 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_3 PF03465.15 PSC74054.1 - 9.7e-24 84.0 0.0 2.2e-23 82.9 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_2 PF03464.15 PSC74054.1 - 2.5e-21 76.4 0.0 4.5e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 mTERF PF02536.14 PSC74055.1 - 0.0083 15.1 0.0 0.011 14.6 0.0 1.2 1 0 0 1 1 1 1 mTERF Carb_anhydrase PF00194.21 PSC74056.1 - 2.2e-23 83.1 0.0 2.5e-16 60.0 0.0 2.0 2 0 0 2 2 2 2 Eukaryotic-type carbonic anhydrase ABC_tran PF00005.27 PSC74057.1 - 7.9e-44 149.5 0.0 2.2e-23 83.3 0.0 2.9 2 0 0 2 2 2 2 ABC transporter ABC_tran_Xtn PF12848.7 PSC74057.1 - 2.8e-20 72.1 12.8 4.4e-20 71.5 2.0 3.3 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 PSC74057.1 - 4.1e-14 53.1 2.9 0.013 15.4 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PSC74057.1 - 2.7e-08 33.5 0.2 0.09 12.2 0.0 4.4 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PSC74057.1 - 5.6e-08 33.3 0.2 0.0028 18.1 0.1 2.6 2 0 0 2 2 2 2 AAA ATPase domain AAA_30 PF13604.6 PSC74057.1 - 8.3e-06 25.7 0.0 0.24 11.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain NACHT PF05729.12 PSC74057.1 - 1.6e-05 24.9 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 2 NACHT domain AAA_29 PF13555.6 PSC74057.1 - 3.3e-05 23.5 0.5 0.048 13.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 PSC74057.1 - 9.7e-05 22.7 0.1 0.68 10.2 0.0 3.1 2 1 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 PSC74057.1 - 0.00018 21.5 0.0 0.14 12.0 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_28 PF13521.6 PSC74057.1 - 0.00021 21.6 4.4 0.029 14.6 0.0 3.0 4 0 0 4 4 2 2 AAA domain MMR_HSR1 PF01926.23 PSC74057.1 - 0.00038 20.5 0.0 0.8 9.8 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.29 PSC74057.1 - 0.00049 20.5 0.0 0.74 10.2 0.0 2.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 PSC74057.1 - 0.00092 19.0 2.9 0.95 9.1 0.0 3.0 4 0 0 4 4 2 2 AAA domain RNA_helicase PF00910.22 PSC74057.1 - 0.0022 18.4 0.0 2.4 8.6 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_13 PF13166.6 PSC74057.1 - 0.0026 16.5 1.3 0.1 11.2 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 PSC74057.1 - 0.006 16.8 1.0 3 8.0 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_15 PF13175.6 PSC74057.1 - 0.0066 16.2 6.7 0.16 11.7 0.3 3.0 4 0 0 4 4 3 2 AAA ATPase domain AAA_23 PF13476.6 PSC74057.1 - 0.0066 17.0 14.8 0.032 14.7 0.2 3.4 4 0 0 4 4 3 2 AAA domain AAA_5 PF07728.14 PSC74057.1 - 0.0099 15.9 0.1 3.7 7.6 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 PSC74057.1 - 0.01 15.0 0.0 3.5 6.7 0.0 2.3 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 PSC74057.1 - 0.011 15.6 0.2 1.5 8.7 0.0 2.8 2 0 0 2 2 2 0 NTPase cobW PF02492.19 PSC74057.1 - 0.012 15.2 0.1 1.3 8.6 0.0 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.6 PSC74057.1 - 0.015 15.3 0.0 11 6.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 PSC74057.1 - 0.018 15.6 1.0 1.7 9.2 0.0 3.4 4 0 0 4 4 3 0 AAA domain DUF87 PF01935.17 PSC74057.1 - 0.018 15.1 0.7 1.3 9.1 0.0 2.6 3 0 0 3 3 2 0 Helicase HerA, central domain AAA_25 PF13481.6 PSC74057.1 - 0.036 13.6 0.0 11 5.5 0.0 3.0 2 0 0 2 2 2 0 AAA domain LpxK PF02606.14 PSC74057.1 - 0.054 12.6 0.1 0.14 11.2 0.1 1.7 1 0 0 1 1 1 0 Tetraacyldisaccharide-1-P 4'-kinase IstB_IS21 PF01695.17 PSC74057.1 - 0.076 12.7 0.1 14 5.3 0.0 2.9 2 0 0 2 2 2 0 IstB-like ATP binding protein Roc PF08477.13 PSC74057.1 - 0.12 12.5 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase SRP54 PF00448.22 PSC74057.1 - 0.14 11.7 1.6 5.4 6.6 0.0 2.8 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 PSC74057.1 - 0.17 11.4 0.0 16 4.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region DAP3 PF10236.9 PSC74057.1 - 1.9 7.6 4.2 6.9 5.7 0.0 2.8 4 0 0 4 4 3 0 Mitochondrial ribosomal death-associated protein 3 DUF3584 PF12128.8 PSC74057.1 - 3.7 4.9 9.1 5.8 4.3 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF3584) Ank_2 PF12796.7 PSC74058.1 - 4.6e-15 56.0 1.6 3.7e-13 49.9 0.9 3.7 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC74058.1 - 2.5e-10 40.7 5.9 1.7e-05 25.3 0.3 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC74058.1 - 5.1e-09 35.6 3.3 0.68 10.7 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 PSC74058.1 - 1.7e-07 31.4 16.3 0.85 10.2 0.1 5.9 5 1 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 PSC74058.1 - 2.5e-06 27.6 11.0 0.00088 19.5 0.2 4.2 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Herpes_DNAp_acc PF04929.12 PSC74058.1 - 2.3 7.1 5.8 4.2 6.2 5.8 1.4 1 0 0 1 1 1 0 Herpes DNA replication accessory factor TFIIA PF03153.13 PSC74059.1 - 0.00039 20.5 21.0 0.00039 20.5 21.0 1.4 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 PSC74059.1 - 0.012 15.2 27.3 0.018 14.6 27.3 1.2 1 0 0 1 1 1 0 Spt20 family DDHD PF02862.17 PSC74059.1 - 0.04 14.1 0.3 0.054 13.7 0.3 1.2 1 0 0 1 1 1 0 DDHD domain DUF2722 PF10846.8 PSC74059.1 - 0.06 12.3 23.0 0.086 11.8 23.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CDC45 PF02724.14 PSC74059.1 - 0.082 11.2 0.8 0.11 10.8 0.8 1.1 1 0 0 1 1 1 0 CDC45-like protein TERB2 PF15101.6 PSC74059.1 - 0.38 10.8 10.7 0.55 10.2 10.7 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Suf PF05843.14 PSC74059.1 - 0.45 10.4 12.1 0.68 9.9 12.1 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) SpoIIP PF07454.11 PSC74059.1 - 0.55 9.6 6.6 0.77 9.2 6.6 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 PSC74059.1 - 0.62 8.8 7.5 1 8.1 7.5 1.2 1 0 0 1 1 1 0 Presenilin Rxt3 PF08642.10 PSC74059.1 - 0.72 10.6 2.9 1.2 9.9 2.9 1.3 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 Band_3_cyto PF07565.13 PSC74059.1 - 1.3 8.8 4.2 1.9 8.3 4.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Neur_chan_memb PF02932.16 PSC74059.1 - 1.7 8.7 2.9 2.5 8.1 2.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 PSC74059.1 - 2.7 7.8 6.1 3.9 7.2 6.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 eIF-3_zeta PF05091.12 PSC74059.1 - 3.1 6.7 13.1 4.3 6.2 13.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ndc1_Nup PF09531.10 PSC74059.1 - 5.3 5.6 6.8 9.9 4.7 6.8 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup UPF0560 PF10577.9 PSC74059.1 - 7.2 5.0 14.1 9.9 4.5 14.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 SRRM_C PF15230.6 PSC74059.1 - 7.2 7.3 8.3 16 6.2 8.3 1.5 1 0 0 1 1 1 0 Serine/arginine repetitive matrix protein C-terminus DUF908 PF06012.12 PSC74059.1 - 8.1 5.8 10.4 13 5.0 10.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Dus PF01207.17 PSC74060.1 - 2.4e-50 171.4 0.0 3.9e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 PSC74060.1 - 8.1e-07 28.7 9.5 6.7e-05 22.6 1.6 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger PEP_mutase PF13714.6 PSC74060.1 - 5e-06 26.2 0.0 1.4e-05 24.7 0.0 1.7 2 0 0 2 2 2 1 Phosphoenolpyruvate phosphomutase zf-CCCH PF00642.24 PSC74060.1 - 0.0001 22.1 0.5 0.0001 22.1 0.5 3.3 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PSC74060.1 - 0.00015 21.7 1.9 0.00015 21.7 1.9 3.0 3 0 0 3 3 3 1 Zinc finger domain Torus PF16131.5 PSC74060.1 - 0.00095 19.8 0.6 0.00095 19.8 0.6 3.1 2 1 1 3 3 3 1 Torus domain zf-CCHH PF10283.9 PSC74060.1 - 3.7 7.6 8.2 13 5.9 0.7 2.6 2 0 0 2 2 2 0 PBZ domain Hint PF01079.20 PSC74061.1 - 4.1e-19 69.0 0.0 6.6e-19 68.3 0.0 1.2 1 0 0 1 1 1 1 Hint module zf-RING_2 PF13639.6 PSC74062.1 - 7.3e-11 42.2 7.4 1.1e-10 41.7 7.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PSC74062.1 - 1.2e-07 31.4 7.5 2e-07 30.7 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PSC74062.1 - 4.5e-06 26.9 7.4 9.9e-06 25.8 7.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 PSC74062.1 - 3.4e-05 23.6 4.3 5.4e-05 23.0 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC74062.1 - 4.3e-05 23.4 6.5 7.1e-05 22.7 6.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 PSC74062.1 - 0.00012 21.7 2.8 0.00021 21.0 2.8 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 PSC74062.1 - 0.00017 21.4 6.4 0.00026 20.8 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PSC74062.1 - 0.0016 18.3 4.4 0.0026 17.6 4.4 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 PSC74062.1 - 0.0033 17.2 3.8 0.0056 16.4 3.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 PSC74062.1 - 0.0048 16.9 5.0 0.0097 15.9 5.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Rtf2 PF04641.12 PSC74062.1 - 0.0064 15.9 0.8 0.0064 15.9 0.8 2.8 2 1 0 2 2 1 1 Rtf2 RING-finger zf-ANAPC11 PF12861.7 PSC74062.1 - 0.015 15.4 2.8 0.028 14.4 2.8 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.11 PSC74062.1 - 0.34 11.2 6.9 0.62 10.4 6.9 1.4 1 0 0 1 1 1 0 RING-like domain Lin-8 PF03353.15 PSC74062.1 - 0.41 10.2 9.3 0.92 9.0 7.8 1.9 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist PHD PF00628.29 PSC74062.1 - 1 9.3 7.8 1.8 8.5 7.8 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_10 PF16685.5 PSC74062.1 - 1.2 9.3 4.1 2 8.6 4.1 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 PSC74062.1 - 1.4 8.6 6.3 2.5 7.8 6.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3H2C3 PF17122.5 PSC74062.1 - 2.6 8.2 4.7 4.5 7.4 4.7 1.4 1 0 0 1 1 1 0 Zinc-finger HAD_2 PF13419.6 PSC74063.1 - 4.5e-22 79.0 0.0 5.3e-22 78.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PSC74063.1 - 7.3e-14 52.6 0.1 2.2e-13 51.0 0.1 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PSC74063.1 - 0.00089 19.7 0.1 0.0016 18.8 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 PSC74063.1 - 0.0013 18.8 0.0 0.14 12.3 0.0 2.6 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PSC74063.1 - 0.0015 18.6 0.0 0.0027 17.7 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Peptidase_C1 PF00112.23 PSC74064.1 - 1.1e-55 189.1 3.2 1.1e-55 189.1 3.2 1.8 2 0 0 2 2 2 1 Papain family cysteine protease AAA PF00004.29 PSC74064.1 - 7e-40 136.5 0.0 2.5e-39 134.7 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Inhibitor_I29 PF08246.12 PSC74064.1 - 1.6e-10 41.2 0.0 3e-10 40.4 0.0 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) AAA_lid_3 PF17862.1 PSC74064.1 - 1.2e-09 37.8 0.2 5.1e-09 35.8 0.2 2.1 1 0 0 1 1 1 1 AAA+ lid domain Peptidase_M41 PF01434.18 PSC74064.1 - 0.00016 21.5 0.0 0.83 9.5 0.0 3.4 4 0 0 4 4 4 2 Peptidase family M41 AAA_5 PF07728.14 PSC74064.1 - 0.00018 21.5 0.1 0.00087 19.3 0.1 2.2 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 PSC74064.1 - 0.00018 21.3 0.0 0.00086 19.1 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Peptidase_C1_2 PF03051.15 PSC74064.1 - 0.00081 18.3 0.1 0.0016 17.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase C1-like family AAA_2 PF07724.14 PSC74064.1 - 0.00084 19.5 0.0 0.00084 19.5 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 PSC74064.1 - 0.0045 16.2 0.0 0.0077 15.5 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 PSC74064.1 - 0.011 15.4 0.0 0.023 14.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 PSC74064.1 - 0.018 14.4 0.1 0.038 13.4 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 PSC74064.1 - 0.053 13.9 0.2 0.053 13.9 0.2 4.2 3 2 0 3 3 2 0 AAA ATPase domain AAA_17 PF13207.6 PSC74064.1 - 0.064 13.7 0.0 0.064 13.7 0.0 3.3 4 0 0 4 4 3 0 AAA domain AAA_22 PF13401.6 PSC74064.1 - 0.068 13.4 0.2 1.3 9.3 0.0 2.7 2 1 0 3 3 3 0 AAA domain AAA_28 PF13521.6 PSC74064.1 - 0.29 11.4 0.0 0.29 11.4 0.0 3.3 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 PSC74064.1 - 0.29 11.3 0.0 0.29 11.3 0.0 2.5 3 0 0 3 3 1 0 AAA domain Presenilin PF01080.17 PSC74064.1 - 4 6.1 5.5 6.6 5.4 5.5 1.3 1 0 0 1 1 1 0 Presenilin DUF2681 PF10883.8 PSC74064.1 - 4.7 7.7 12.3 6.1 7.3 10.1 2.4 2 0 0 2 2 1 0 Protein of unknown function (DUF2681) Pannexin_like PF12534.8 PSC74064.1 - 6.4 5.8 4.7 12 4.9 4.7 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 AAA PF00004.29 PSC74065.1 - 3.8e-12 46.8 0.0 6e-12 46.1 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Acetyltransf_1 PF00583.25 PSC74066.1 - 1.7e-07 31.5 0.0 3.6e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF2256 PF10013.9 PSC74066.1 - 8.1e-07 29.1 0.7 2.3e-06 27.6 0.7 1.8 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2256) Acetyltransf_10 PF13673.7 PSC74066.1 - 2e-06 27.7 0.0 6.9e-06 26.0 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC74066.1 - 5.5e-05 23.1 0.0 0.00013 21.9 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 PSC74066.1 - 7.2e-05 23.1 0.0 0.00017 22.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PSC74066.1 - 0.00011 22.3 0.1 0.0005 20.1 0.0 2.1 3 0 0 3 3 3 1 Acetyltransferase (GNAT) domain Glyoxalase_6 PF18029.1 PSC74066.1 - 0.00085 20.1 1.1 0.031 15.1 0.0 3.2 2 1 0 2 2 2 1 Glyoxalase-like domain Aa_trans PF01490.18 PSC74067.1 - 5.9e-73 245.9 25.4 6.8e-73 245.7 25.4 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 PSC74067.1 - 4e-05 22.8 11.7 4e-05 22.8 11.7 2.0 2 1 0 2 2 2 1 Tryptophan/tyrosine permease family Colicin PF01024.19 PSC74067.1 - 6.2 6.7 6.3 0.4 10.5 0.1 2.2 3 0 0 3 3 3 0 Colicin pore forming domain Acatn PF13000.7 PSC74068.1 - 2.2e-128 429.2 6.3 1.7e-92 310.7 6.9 3.9 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 Abhydrolase_1 PF00561.20 PSC74069.1 - 6.1e-08 32.6 0.2 2.3e-07 30.7 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC74069.1 - 1.2e-06 28.0 0.1 6.9e-06 25.5 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 PSC74069.1 - 0.01 15.3 0.0 0.074 12.5 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family Peptidase_S28 PF05577.12 PSC74069.1 - 0.018 13.8 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 Serine carboxypeptidase S28 LIDHydrolase PF10230.9 PSC74069.1 - 0.12 11.9 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Lipase_3 PF01764.25 PSC74069.1 - 0.15 11.9 0.0 0.36 10.7 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Pkinase PF00069.25 PSC74070.1 - 4.9e-17 62.2 0.0 8.1e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74070.1 - 1.9e-09 37.2 0.0 4.7e-09 35.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PSC74071.1 - 2.6e-10 39.9 3.5 8.3e-09 35.1 0.0 4.3 5 1 1 6 6 6 1 Leucine rich repeat LRR_4 PF12799.7 PSC74071.1 - 1.1e-08 35.2 0.1 0.00035 20.9 0.0 4.9 5 1 1 6 6 6 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PSC74071.1 - 0.0064 16.9 2.0 67 4.6 0.0 5.3 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 PSC74071.1 - 0.043 13.9 9.9 8.4 6.7 0.0 5.3 5 0 0 5 5 5 0 Leucine Rich repeat AATF-Che1 PF13339.6 PSC74072.1 - 1.4e-22 80.9 0.0 2.4e-21 76.9 0.0 2.5 2 0 0 2 2 2 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 PSC74072.1 - 4.8e-19 68.7 0.1 1.5e-18 67.0 0.0 2.0 2 0 0 2 2 2 1 Apoptosis-antagonizing transcription factor, C-terminal DUF4350 PF14258.6 PSC74072.1 - 0.057 13.8 1.1 5.7 7.4 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4350) DUF2259 PF10016.9 PSC74072.1 - 0.084 12.8 0.2 0.084 12.8 0.2 2.1 2 0 0 2 2 2 0 Predicted secreted protein (DUF2259) ADIP PF11559.8 PSC74072.1 - 6.6 6.8 7.1 6 6.9 0.3 2.4 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding ThrE PF06738.12 PSC74074.1 - 0.051 12.9 0.0 0.077 12.3 0.0 1.2 1 0 0 1 1 1 0 Putative threonine/serine exporter DUF4140 PF13600.6 PSC74074.1 - 5.8 7.4 6.0 18 5.8 4.6 2.2 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) ALMT PF11744.8 PSC74075.1 - 1.8e-10 40.3 1.5 2.6e-10 39.7 1.5 1.1 1 0 0 1 1 1 1 Aluminium activated malate transporter FUSC_2 PF13515.6 PSC74075.1 - 3.8e-08 33.5 7.5 7.2e-08 32.6 7.5 1.4 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.12 PSC74075.1 - 2.6e-07 29.6 8.8 2.6e-07 29.6 8.8 3.4 3 1 0 3 3 3 1 Fusaric acid resistance protein family zf-C3HC4_2 PF13923.6 PSC74076.1 - 6.4e-08 32.3 10.9 1.9e-07 30.8 11.1 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC74076.1 - 1.2e-07 31.4 8.6 2e-07 30.8 8.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC74076.1 - 1.4e-07 31.4 5.8 1.4e-07 31.4 5.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 PSC74076.1 - 3.8e-07 30.3 12.8 5.6e-07 29.8 12.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PSC74076.1 - 4.3e-07 29.7 10.5 6.6e-07 29.1 10.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC74076.1 - 6.8e-06 26.0 9.7 1e-05 25.4 9.7 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PSC74076.1 - 0.0001 22.4 13.0 0.00016 21.7 13.0 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 PSC74076.1 - 0.00031 20.5 8.3 0.0005 19.9 8.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PSC74076.1 - 0.0027 17.7 3.6 0.0041 17.1 3.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 PSC74076.1 - 0.018 15.3 8.4 0.034 14.4 8.4 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain Baculo_IE-1 PF05290.11 PSC74076.1 - 0.022 14.7 4.9 0.032 14.2 4.9 1.2 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_10 PF16685.5 PSC74076.1 - 0.063 13.4 7.7 0.12 12.6 7.7 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 U-box PF04564.15 PSC74076.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 U-box domain TFIIA PF03153.13 PSC74077.1 - 4.4 7.2 9.5 6.9 6.5 9.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0047 PF01894.17 PSC74078.1 - 2.6e-23 82.3 0.0 2.9e-23 82.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0047 UPF0047 PF01894.17 PSC74079.1 - 5e-27 94.3 0.0 3.6e-26 91.6 0.0 1.9 1 1 0 1 1 1 1 Uncharacterised protein family UPF0047 Ribosomal_S21e PF01249.18 PSC74080.1 - 3.1e-37 126.5 0.0 3.5e-37 126.3 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Pkinase PF00069.25 PSC74081.1 - 3.6e-67 226.5 0.0 6.7e-67 225.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74081.1 - 3.5e-32 111.7 0.0 6e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Barwin PF00967.17 PSC74081.1 - 1.5e-27 95.8 1.9 5.2e-27 94.0 1.9 1.9 1 0 0 1 1 1 1 Barwin family EF-hand_5 PF13202.6 PSC74081.1 - 6.1e-16 57.1 0.8 0.00054 19.3 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 PSC74081.1 - 7.6e-14 51.9 0.0 2.5e-07 31.0 0.0 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PSC74081.1 - 3.6e-13 48.0 0.0 0.0073 15.8 0.0 3.8 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 PSC74081.1 - 2.3e-10 40.2 0.0 2.1e-06 27.5 0.0 3.4 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 PSC74081.1 - 1e-09 37.5 0.1 0.091 12.7 0.0 3.9 4 0 0 4 4 3 3 EF-hand domain Kinase-like PF14531.6 PSC74081.1 - 0.0016 17.8 7.7 0.0017 17.7 0.0 3.2 3 1 0 3 3 2 1 Kinase-like TFIIA PF03153.13 PSC74081.1 - 0.025 14.6 15.9 0.041 13.9 15.9 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SPARC_Ca_bdg PF10591.9 PSC74081.1 - 0.29 11.5 2.1 1.1 9.5 0.0 2.8 2 2 0 2 2 1 0 Secreted protein acidic and rich in cysteine Ca binding region DDHD PF02862.17 PSC74081.1 - 0.92 9.6 3.2 2 8.5 3.2 1.6 1 0 0 1 1 1 0 DDHD domain Complex1_LYR_2 PF13233.6 PSC74081.1 - 1.6 9.5 7.3 21 5.9 0.0 2.7 2 0 0 2 2 2 0 Complex1_LYR-like XRN_M PF17846.1 PSC74081.1 - 5.6 5.8 10.7 8.1 5.3 10.7 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Asp-B-Hydro_N PF05279.11 PSC74081.1 - 8.2 6.4 25.3 4.9 7.1 23.4 1.5 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region Sugar_tr PF00083.24 PSC74082.1 - 2e-94 317.0 11.9 2.4e-94 316.7 11.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PSC74082.1 - 3.2e-26 92.1 40.0 3.2e-26 92.1 40.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily BTB PF00651.31 PSC74082.1 - 0.0035 17.6 0.0 0.008 16.4 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain Enolase_C PF00113.22 PSC74083.1 - 7.4e-146 485.0 0.2 9.9e-146 484.6 0.2 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 PSC74083.1 - 9.1e-57 190.9 0.3 2.1e-56 189.7 0.3 1.7 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 PSC74083.1 - 2.3e-08 33.9 0.2 1.5e-07 31.2 0.0 2.3 2 0 0 2 2 2 1 Enolase C-terminal domain-like MAAL_C PF07476.11 PSC74083.1 - 1.9e-06 27.3 0.1 3.6e-06 26.3 0.1 1.4 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus PS-DH PF14765.6 PSC74084.1 - 5.2e-06 25.9 0.1 5.4e-06 25.9 0.1 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase DUF4080 PF13311.6 PSC74084.1 - 0.096 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) Kinesin PF00225.23 PSC74086.1 - 5e-95 318.2 0.3 7e-95 317.7 0.0 1.4 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PSC74086.1 - 3.1e-21 75.9 0.4 5.4e-21 75.1 0.0 1.6 2 0 0 2 2 2 1 Microtubule binding TFIIA PF03153.13 PSC74086.1 - 1.5 8.7 15.5 3.4 7.6 15.5 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SBP PF03110.14 PSC74087.1 - 9.6e-27 93.1 13.3 2.3e-26 91.9 13.3 1.7 1 0 0 1 1 1 1 SBP domain Helicase_RecD PF05127.14 PSC74087.1 - 0.19 11.5 1.3 0.39 10.5 1.3 1.5 1 0 0 1 1 1 0 Helicase FAM199X PF15814.5 PSC74087.1 - 0.6 9.1 7.4 1.4 7.9 7.4 1.5 1 0 0 1 1 1 0 Protein family FAM199X Endostatin PF06482.11 PSC74087.1 - 3.6 7.0 16.1 4.5 6.6 5.4 2.4 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Pkinase PF00069.25 PSC74088.1 - 2.8e-70 236.7 0.0 3.3e-70 236.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74088.1 - 1.8e-31 109.4 0.0 2.3e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PSC74088.1 - 8.4e-06 25.3 0.1 1.3e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PSC74088.1 - 1.3e-05 24.6 0.0 8.3e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 PSC74088.1 - 1.9e-05 23.7 0.0 3.3e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 PSC74088.1 - 0.00013 21.1 0.0 0.00021 20.3 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 PSC74088.1 - 0.0091 15.9 0.8 0.67 9.8 0.4 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.22 PSC74088.1 - 0.16 11.6 0.1 0.24 11.0 0.1 1.2 1 0 0 1 1 1 0 RIO1 family dUTPase PF00692.19 PSC74089.1 - 8.5e-44 148.4 0.0 1e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 dUTPase DCD PF06559.11 PSC74089.1 - 0.021 13.6 0.0 0.026 13.3 0.0 1.1 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) DUF5429 PF17494.2 PSC74089.1 - 0.22 11.6 0.8 16 5.6 0.1 2.8 3 1 0 3 3 3 0 Family of unknown function (DUF5429) 60KD_IMP PF02096.20 PSC74090.1 - 2.6e-47 160.8 0.0 3.4e-47 160.4 0.0 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein NAD_binding_10 PF13460.6 PSC74091.1 - 4.1e-34 118.1 0.0 4.1e-34 118.1 0.0 4.1 3 1 1 4 4 4 1 NAD(P)H-binding NmrA PF05368.13 PSC74091.1 - 7e-11 42.1 0.0 7e-11 42.1 0.0 2.3 3 0 0 3 3 3 1 NmrA-like family Epimerase PF01370.21 PSC74091.1 - 5.4e-05 22.8 1.8 0.00015 21.3 0.1 2.5 3 0 0 3 3 3 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PSC74091.1 - 0.00022 20.3 1.1 0.0012 18.0 0.0 2.1 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 PSC74091.1 - 0.0016 17.7 6.1 0.0075 15.5 0.1 3.3 3 0 0 3 3 3 1 Male sterility protein DapB_N PF01113.20 PSC74091.1 - 0.091 12.9 0.0 0.47 10.6 0.0 2.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Methyltrans_SAM PF10672.9 PSC74091.1 - 0.2 10.8 0.1 0.48 9.5 0.1 1.6 1 0 0 1 1 1 0 S-adenosylmethionine-dependent methyltransferase Methyltransf_25 PF13649.6 PSC74092.1 - 9.2e-12 45.5 0.1 2.8e-11 44.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC74092.1 - 6.5e-10 39.5 0.0 1.3e-09 38.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC74092.1 - 6.6e-10 39.6 0.0 1.1e-09 38.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC74092.1 - 5e-08 32.9 0.0 6.4e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC74092.1 - 7.6e-08 32.4 0.0 1.2e-07 31.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PSC74092.1 - 0.006 16.1 0.0 0.012 15.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_33 PF10017.9 PSC74092.1 - 0.0097 15.1 0.0 0.028 13.6 0.0 1.8 2 1 0 2 2 2 1 Histidine-specific methyltransferase, SAM-dependent NNMT_PNMT_TEMT PF01234.17 PSC74092.1 - 0.1 11.7 0.0 0.31 10.2 0.0 1.7 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family Pox_MCEL PF03291.16 PSC74092.1 - 0.16 11.1 0.1 0.22 10.6 0.1 1.2 1 0 0 1 1 1 0 mRNA capping enzyme RRM_1 PF00076.22 PSC74093.1 - 3.3e-11 42.8 0.0 1.9e-05 24.4 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Agenet PF05641.12 PSC74093.1 - 2.2e-07 31.2 1.4 1.1e-05 25.8 0.2 2.7 2 0 0 2 2 2 1 Agenet domain AF-4 PF05110.13 PSC74093.1 - 0.0019 16.4 29.4 0.0028 15.9 29.4 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein RRM_7 PF16367.5 PSC74093.1 - 0.086 13.0 0.0 0.28 11.3 0.0 2.0 1 0 0 1 1 1 0 RNA recognition motif DEAD PF00270.29 PSC74094.1 - 2.8e-46 157.5 0.0 4.2e-45 153.7 0.0 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC74094.1 - 4.1e-30 104.4 0.0 9e-30 103.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC74094.1 - 2e-05 24.6 0.0 0.00025 21.1 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Rhodanese PF00581.20 PSC74094.1 - 0.1 13.1 0.0 0.25 11.9 0.0 1.7 1 0 0 1 1 1 0 Rhodanese-like domain PP2C PF00481.21 PSC74095.1 - 7.1e-75 252.0 0.1 1.2e-60 205.4 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C PP2C PF00481.21 PSC74096.1 - 7.1e-75 252.0 0.1 1.2e-60 205.4 0.0 2.1 2 0 0 2 2 2 2 Protein phosphatase 2C RNase_HII PF01351.18 PSC74097.1 - 7.3e-49 166.3 0.0 9.4e-49 165.9 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease HII Sec7 PF01369.20 PSC74098.1 - 7.6e-52 175.6 0.0 1.1e-51 175.1 0.0 1.2 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 PSC74098.1 - 7.5e-24 84.4 0.0 2.3e-23 82.9 0.0 1.8 2 0 0 2 2 2 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DCB PF16213.5 PSC74098.1 - 2.6e-14 53.3 0.0 5.6e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Dimerisation and cyclophilin-binding domain of Mon2 DUF1981 PF09324.10 PSC74098.1 - 1.2e-13 50.8 0.0 4e-13 49.0 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1981) HEAT PF02985.22 PSC74098.1 - 5.5 7.5 16.1 37 5.0 0.2 6.7 5 0 0 5 5 5 0 HEAT repeat CmcI PF04989.12 PSC74099.1 - 5.9e-47 160.0 0.0 9.7e-47 159.3 0.0 1.3 1 0 0 1 1 1 1 Cephalosporin hydroxylase Glycos_transf_1 PF00534.20 PSC74099.1 - 1.4e-32 112.6 0.0 2.6e-32 111.7 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PSC74099.1 - 4.5e-31 108.1 0.2 1e-29 103.6 0.2 2.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 PSC74099.1 - 5.8e-25 88.3 0.2 1.7e-23 83.5 0.1 2.5 2 0 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 PSC74099.1 - 2e-16 60.8 1.1 2e-16 60.8 1.1 3.6 3 1 0 3 3 3 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 PSC74099.1 - 1.1e-09 38.6 0.0 4.2e-09 36.7 0.0 2.0 1 0 0 1 1 1 1 Glycosyl transferases group 1 Methyltransf_24 PF13578.6 PSC74099.1 - 1.6e-08 35.5 0.0 6.1e-08 33.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Glyco_trans_4_2 PF13477.6 PSC74099.1 - 2.9e-06 27.4 0.0 4.5e-05 23.5 0.0 2.6 2 1 0 2 2 2 1 Glycosyl transferase 4-like Piezo_RRas_bdg PF12166.8 PSC74100.1 - 0.17 11.1 0.6 0.29 10.4 0.6 1.3 1 0 0 1 1 1 0 Piezo non-specific cation channel, R-Ras-binding domain Mcm10 PF09332.11 PSC74100.1 - 0.86 9.0 5.1 1.5 8.2 5.1 1.3 1 0 0 1 1 1 0 Mcm10 replication factor Herpes_BLRF2 PF05812.12 PSC74101.1 - 0.0012 19.0 1.8 0.071 13.3 0.3 2.4 2 0 0 2 2 2 1 Herpesvirus BLRF2 protein Nnf1 PF03980.14 PSC74101.1 - 0.0096 16.3 9.5 0.0096 16.3 9.5 2.4 2 1 1 3 3 3 1 Nnf1 Syntaxin PF00804.25 PSC74101.1 - 0.087 12.5 4.2 0.16 11.6 4.2 1.3 1 0 0 1 1 1 0 Syntaxin JIP_LZII PF16471.5 PSC74101.1 - 0.1 12.8 5.4 3.9 7.7 0.2 2.4 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II TSC22 PF01166.18 PSC74101.1 - 0.23 11.8 1.2 6.2 7.2 0.2 2.8 2 0 0 2 2 2 0 TSC-22/dip/bun family TMF_DNA_bd PF12329.8 PSC74101.1 - 3.4 7.7 8.5 1.2 9.2 3.5 2.4 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding Pex14_N PF04695.13 PSC74101.1 - 3.5 8.3 17.4 0.18 12.4 9.1 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HALZ PF02183.18 PSC74101.1 - 4.9 7.5 11.4 2.8 8.2 0.3 3.5 4 0 0 4 4 4 0 Homeobox associated leucine zipper bZIP_1 PF00170.21 PSC74101.1 - 6.9 6.9 11.3 10 6.3 3.5 3.2 2 1 1 3 3 3 0 bZIP transcription factor DUF2163 PF09931.9 PSC74101.1 - 8.6 6.5 7.0 21 5.3 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2163) CbiX PF01903.17 PSC74102.1 - 4.6e-28 97.7 0.2 8.1e-28 96.9 0.2 1.4 1 0 0 1 1 1 1 CbiX CbiK PF06180.11 PSC74102.1 - 0.0022 17.4 0.0 0.003 16.9 0.0 1.1 1 0 0 1 1 1 1 Cobalt chelatase (CbiK) Pkinase PF00069.25 PSC74103.1 - 3.4e-67 226.6 0.0 4.4e-67 226.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74103.1 - 5e-40 137.4 0.0 7.5e-40 136.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 PSC74103.1 - 3.2e-05 22.9 0.0 6e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 PSC74103.1 - 0.00019 20.9 0.0 0.03 13.7 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 PSC74103.1 - 0.2 11.0 0.0 0.36 10.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-C2H2_10 PF16588.5 PSC74104.1 - 0.18 11.5 1.5 0.18 11.5 1.5 2.4 2 0 0 2 2 2 0 C2H2 zinc-finger Peptidase_C48 PF02902.19 PSC74105.1 - 1.4e-35 123.2 0.2 2e-35 122.6 0.2 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MazE_antitoxin PF04014.18 PSC74105.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin BAF1_ABF1 PF04684.13 PSC74105.1 - 2.3 7.2 6.9 3.2 6.7 6.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Cwf_Cwc_15 PF04889.12 PSC74105.1 - 4.4 7.0 13.6 11 5.6 13.6 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Peptidase_C48 PF02902.19 PSC74106.1 - 1.3e-35 123.2 0.2 2e-35 122.6 0.2 1.2 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain MazE_antitoxin PF04014.18 PSC74106.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Antidote-toxin recognition MazE, bacterial antitoxin Cwf_Cwc_15 PF04889.12 PSC74106.1 - 4.8 6.8 13.8 12 5.5 13.8 1.6 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BAF1_ABF1 PF04684.13 PSC74106.1 - 5.2 6.0 8.2 7.5 5.5 8.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Rad9 PF04139.13 PSC74107.1 - 1.5e-48 165.5 0.0 1.8e-48 165.2 0.0 1.1 1 0 0 1 1 1 1 Rad9 Draxin PF15550.6 PSC74107.1 - 0.076 12.9 2.6 0.11 12.3 2.6 1.2 1 0 0 1 1 1 0 Draxin Lin-8 PF03353.15 PSC74107.1 - 0.63 9.6 5.2 0.9 9.0 5.2 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.9 PSC74107.1 - 5.4 5.1 11.7 7.4 4.7 11.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Chorismate_synt PF01264.21 PSC74108.1 - 2.8e-138 460.1 1.2 3.2e-138 459.9 1.2 1.0 1 0 0 1 1 1 1 Chorismate synthase Tub PF01167.18 PSC74109.1 - 2.3e-78 263.3 0.0 3e-78 262.9 0.0 1.1 1 0 0 1 1 1 1 Tub family DUF3527 PF12043.8 PSC74109.1 - 0.13 11.9 0.0 0.5 9.9 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3527) RicinB_lectin_2 PF14200.6 PSC74111.1 - 0.00061 20.5 0.7 0.054 14.2 0.1 2.8 1 1 3 4 4 4 2 Ricin-type beta-trefoil lectin domain-like Ceramidse_alk_C PF17048.5 PSC74111.1 - 0.0022 17.9 0.2 0.011 15.6 0.1 2.0 2 1 0 2 2 2 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal NAR2 PF16974.5 PSC74111.1 - 0.046 13.1 1.3 0.17 11.3 0.2 2.1 2 0 0 2 2 2 0 High-affinity nitrate transporter accessory YcgR PF07317.12 PSC74111.1 - 0.17 11.8 0.0 1.3 9.0 0.0 2.2 2 1 0 2 2 2 0 Flagellar regulator YcgR Syntaxin PF00804.25 PSC74112.1 - 2.6e-69 232.9 12.2 3.8e-69 232.4 12.2 1.2 1 0 0 1 1 1 1 Syntaxin ADK PF00406.22 PSC74112.1 - 1.5e-24 86.8 1.8 2.2e-24 86.3 0.0 2.1 2 1 0 2 2 2 1 Adenylate kinase SNARE PF05739.19 PSC74112.1 - 3.6e-15 55.7 0.8 9.6e-15 54.3 0.8 1.8 1 0 0 1 1 1 1 SNARE domain AAA_17 PF13207.6 PSC74112.1 - 1.4e-11 45.0 6.8 3.9e-10 40.3 0.0 3.4 2 1 1 3 3 3 1 AAA domain Nnf1 PF03980.14 PSC74112.1 - 0.00054 20.3 0.5 0.00054 20.3 0.5 2.4 3 0 0 3 3 3 1 Nnf1 MSP1_C PF07462.11 PSC74112.1 - 0.0061 15.3 0.4 0.08 11.6 0.0 2.2 1 1 1 2 2 2 1 Merozoite surface protein 1 (MSP1) C-terminus SRP54 PF00448.22 PSC74112.1 - 0.026 14.2 0.0 0.052 13.2 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Syntaxin_2 PF14523.6 PSC74112.1 - 0.029 14.7 0.5 0.029 14.7 0.5 2.0 2 0 0 2 2 2 0 Syntaxin-like protein ADK_lid PF05191.14 PSC74112.1 - 0.042 13.8 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 Adenylate kinase, active site lid AAA_16 PF13191.6 PSC74112.1 - 0.15 12.5 0.8 0.52 10.7 0.0 2.3 2 2 0 2 2 2 0 AAA ATPase domain DUF632 PF04782.12 PSC74112.1 - 0.41 9.9 6.2 0.72 9.1 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF632) Mto2_bdg PF12808.7 PSC74112.1 - 2.4 8.5 6.5 25 5.3 2.2 3.1 2 0 0 2 2 2 0 Micro-tubular organiser Mto1 C-term Mto2-binding region OmpH PF03938.14 PSC74112.1 - 5.8 7.2 9.6 59 4.0 9.6 2.6 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) Pterin_4a PF01329.19 PSC74113.1 - 4.1e-10 39.7 0.0 4.6e-10 39.5 0.0 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase CCB2_CCB4 PF11152.8 PSC74114.1 - 4.6e-59 199.0 0.3 5.8e-59 198.7 0.3 1.1 1 0 0 1 1 1 1 Cofactor assembly of complex C subunit B, CCB2/CCB4 GAF_2 PF13185.6 PSC74114.1 - 0.00022 21.5 0.8 0.00085 19.6 0.2 2.1 2 1 0 2 2 2 1 GAF domain Mitofilin PF09731.9 PSC74115.1 - 1.6e-35 123.1 29.9 1.6e-35 123.1 29.9 3.2 3 0 0 3 3 3 1 Mitochondrial inner membrane protein PHTB1_C PF14728.6 PSC74115.1 - 3 6.8 7.3 4.7 6.2 7.3 1.2 1 0 0 1 1 1 0 PTHB1 C-terminus Chloroa_b-bind PF00504.21 PSC74116.1 - 5.6e-09 36.7 0.1 4.9e-06 27.2 0.0 2.0 1 1 1 2 2 2 2 Chlorophyll A-B binding protein Alba PF01918.21 PSC74117.1 - 6.1e-11 42.0 0.0 9.8e-11 41.3 0.0 1.2 1 0 0 1 1 1 1 Alba XRN_M PF17846.1 PSC74117.1 - 0.31 10.0 5.4 0.37 9.7 5.4 1.2 1 0 0 1 1 1 0 Xrn1 helical domain PPP4R2 PF09184.11 PSC74117.1 - 0.5 9.9 5.8 0.57 9.7 5.8 1.1 1 0 0 1 1 1 0 PPP4R2 Presenilin PF01080.17 PSC74117.1 - 4 6.1 9.1 4.8 5.8 9.1 1.1 1 0 0 1 1 1 0 Presenilin DUF4746 PF15928.5 PSC74117.1 - 6.7 6.0 14.5 8.1 5.8 14.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Asp-B-Hydro_N PF05279.11 PSC74117.1 - 7 6.6 20.2 8.4 6.4 20.2 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Hid1 PF12722.7 PSC74117.1 - 7.2 4.6 5.1 8.1 4.4 5.1 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Borrelia_P83 PF05262.11 PSC74117.1 - 7.7 4.9 21.0 8.1 4.8 21.0 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein SAPS PF04499.15 PSC74117.1 - 9.6 4.9 7.4 11 4.6 7.4 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein Nucleotid_trans PF03407.16 PSC74118.1 - 0.017 15.1 0.0 0.045 13.7 0.0 1.6 1 1 0 1 1 1 0 Nucleotide-diphospho-sugar transferase Pkinase PF00069.25 PSC74119.1 - 8.3e-65 218.8 0.0 9.5e-65 218.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74119.1 - 1.5e-25 90.0 0.0 3.5e-25 88.8 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PSC74119.1 - 0.00022 21.2 0.1 0.035 14.0 0.2 2.4 2 0 0 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 PSC74119.1 - 0.0021 17.4 0.0 0.0032 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PSC74119.1 - 0.13 11.8 0.1 0.64 9.6 0.0 1.8 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 AMP-binding PF00501.28 PSC74120.1 - 4.5e-72 243.0 0.1 5.2e-72 242.7 0.1 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PSC74120.1 - 1.3e-19 70.9 0.1 3.5e-19 69.5 0.1 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain T2SS-T3SS_pil_N PF13629.6 PSC74120.1 - 0.068 12.9 0.1 0.14 11.9 0.1 1.5 1 0 0 1 1 1 0 Pilus formation protein N terminal region RNase_PH PF01138.21 PSC74121.1 - 1.6e-12 48.1 0.3 3.8e-12 46.8 0.3 1.6 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 Pkinase PF00069.25 PSC74122.1 - 3.2e-64 216.9 0.0 5.2e-64 216.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74122.1 - 1.8e-28 99.6 0.0 1e-26 93.8 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PSC74122.1 - 0.11 11.8 0.4 0.69 9.2 0.1 2.0 1 1 1 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PSC74122.1 - 0.57 10.1 0.0 0.57 10.1 0.0 3.1 2 2 1 3 3 3 0 Phosphotransferase enzyme family RuBisCO_small PF00101.20 PSC74123.1 - 1.1e-77 256.1 0.0 4.1e-39 132.5 0.0 2.5 2 0 0 2 2 2 2 Ribulose bisphosphate carboxylase, small chain Thioredoxin PF00085.20 PSC74123.1 - 6e-33 112.9 0.0 4.2e-15 55.6 0.0 2.4 2 0 0 2 2 2 2 Thioredoxin Nup88 PF10168.9 PSC74123.1 - 3.4e-18 64.9 0.0 1e-10 40.1 0.0 3.1 3 0 0 3 3 3 3 Nuclear pore component Thioredoxin_8 PF13905.6 PSC74123.1 - 1.1e-07 32.0 0.0 0.0033 17.7 0.0 3.4 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 PSC74123.1 - 3.7e-07 30.6 0.1 0.21 12.0 0.0 4.0 2 2 0 2 2 2 2 Thioredoxin-like domain Phosducin PF02114.16 PSC74123.1 - 0.00013 21.0 0.0 0.00021 20.3 0.0 1.2 1 0 0 1 1 1 1 Phosducin AhpC-TSA PF00578.21 PSC74123.1 - 0.00048 20.0 0.0 1.1 9.2 0.0 2.6 2 0 0 2 2 2 2 AhpC/TSA family OST3_OST6 PF04756.13 PSC74123.1 - 0.0037 16.7 0.0 0.86 8.9 0.0 2.2 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 PSC74123.1 - 0.0082 15.9 0.0 0.7 9.7 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin Spc7 PF08317.11 PSC74123.1 - 0.021 13.7 8.5 0.11 11.3 0.2 2.1 2 0 0 2 2 2 0 Spc7 kinetochore protein ANAPC4_WD40 PF12894.7 PSC74123.1 - 0.022 15.0 0.0 0.19 12.0 0.0 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain DUF1857 PF08982.11 PSC74123.1 - 0.052 13.4 0.0 20 5.0 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1857) Thioredoxin_7 PF13899.6 PSC74123.1 - 0.13 12.5 0.0 11 6.3 0.0 2.7 2 0 0 2 2 2 0 Thioredoxin-like BRE1 PF08647.11 PSC74123.1 - 2 8.6 7.1 0.7 10.0 0.3 2.8 3 0 0 3 3 3 0 BRE1 E3 ubiquitin ligase Pkinase PF00069.25 PSC74124.1 - 3.1e-65 220.2 0.0 3.8e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74124.1 - 1.5e-24 86.7 0.0 1.9e-24 86.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC74124.1 - 5.4e-07 29.2 0.0 0.00015 21.2 0.0 2.2 1 1 1 2 2 2 2 Kinase-like Choline_kinase PF01633.20 PSC74124.1 - 0.0046 16.6 0.2 0.007 16.0 0.2 1.2 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 PSC74124.1 - 0.01 15.2 0.3 0.016 14.6 0.3 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PSC74124.1 - 0.019 14.6 0.0 0.033 13.8 0.0 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 PSC74124.1 - 0.035 14.0 0.1 0.11 12.4 0.1 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family tRNA-synt_1b PF00579.25 PSC74125.1 - 1.1e-15 57.8 0.0 4.4e-15 55.8 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Peptidase_C1 PF00112.23 PSC74126.1 - 3.9e-74 249.4 0.0 8.7e-50 169.8 0.0 2.2 1 1 1 2 2 2 2 Papain family cysteine protease Inhibitor_I29 PF08246.12 PSC74126.1 - 8.2e-12 45.4 1.4 1.2e-11 44.8 1.4 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PSC74126.1 - 1e-06 27.8 1.5 0.1 11.4 0.0 3.1 3 0 0 3 3 3 3 Peptidase C1-like family FAD_binding_3 PF01494.19 PSC74126.1 - 3.3e-05 23.3 1.6 0.014 14.6 0.1 3.1 3 0 0 3 3 3 1 FAD binding domain Trp_halogenase PF04820.14 PSC74126.1 - 0.00073 18.5 2.0 0.29 9.9 0.0 3.0 3 0 0 3 3 3 2 Tryptophan halogenase Pyr_redox_2 PF07992.14 PSC74126.1 - 0.011 15.0 0.5 0.12 11.6 0.5 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PSC74126.1 - 0.019 13.7 0.1 0.083 11.6 0.1 1.8 2 0 0 2 2 2 0 HI0933-like protein MCM_bind PF09739.9 PSC74127.1 - 1.6e-121 406.6 0.0 1.9e-121 406.4 0.0 1.0 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor MCM_bind PF09739.9 PSC74128.1 - 1e-120 404.0 0.0 1.2e-120 403.7 0.0 1.0 1 0 0 1 1 1 1 Mini-chromosome maintenance replisome factor BRCT_2 PF16589.5 PSC74129.1 - 1.1e-12 48.1 0.0 0.0012 19.2 0.0 4.2 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 PSC74129.1 - 5.1e-06 26.8 0.0 0.0014 19.0 0.0 3.4 4 0 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 PSC74129.1 - 2e-05 24.4 0.0 0.0018 18.1 0.0 2.3 2 0 0 2 2 2 2 Regulator of Ty1 transposition protein 107 BRCT domain BRCT_2 PF16589.5 PSC74130.1 - 1.7e-11 44.4 0.0 0.018 15.5 0.0 4.2 4 0 0 4 4 4 3 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 PSC74130.1 - 2e-05 24.4 0.0 0.0018 18.1 0.0 2.3 2 0 0 2 2 2 2 Regulator of Ty1 transposition protein 107 BRCT domain BRCT PF00533.26 PSC74130.1 - 3.6e-05 24.0 0.0 0.0014 19.0 0.0 3.0 4 0 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain NAD_kinase PF01513.21 PSC74131.1 - 3.9e-50 170.7 0.0 1.2e-49 169.1 0.0 1.8 1 1 0 1 1 1 1 ATP-NAD kinase FeS_assembly_P PF01883.19 PSC74131.1 - 1.7e-12 47.3 0.0 3.8e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein Pex14_N PF04695.13 PSC74131.1 - 0.029 15.0 4.8 0.051 14.2 4.8 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 PSC74131.1 - 0.031 14.3 11.4 0.046 13.7 11.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DLIC PF05783.11 PSC74131.1 - 0.035 12.9 4.0 0.051 12.4 4.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DAGK_cat PF00781.24 PSC74131.1 - 0.043 13.4 1.5 0.064 12.9 0.0 2.0 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain V4R PF02830.18 PSC74131.1 - 0.08 13.0 0.0 0.32 11.0 0.0 2.0 2 0 0 2 2 2 0 V4R domain DUF2722 PF10846.8 PSC74131.1 - 0.16 10.9 10.1 0.22 10.4 10.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 PSC74131.1 - 3.1 7.3 20.7 4.9 6.7 20.7 1.2 1 0 0 1 1 1 0 Spt20 family FA_hydroxylase PF04116.13 PSC74132.1 - 1.3e-25 90.3 12.3 3.3e-25 89.0 9.9 2.6 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily PAP_fibrillin PF04755.12 PSC74132.1 - 5e-11 42.9 0.0 5.1e-05 23.3 0.0 2.2 2 0 0 2 2 2 2 PAP_fibrillin DUF179 PF02622.15 PSC74133.1 - 4.9e-19 68.9 0.0 1.5e-18 67.3 0.0 1.8 1 1 0 1 1 1 1 Uncharacterized ACR, COG1678 RINGv PF12906.7 PSC74133.1 - 3.7e-08 33.4 9.8 6.2e-08 32.7 9.8 1.4 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.6 PSC74133.1 - 0.49 10.8 7.3 0.93 9.9 7.3 1.5 1 0 0 1 1 1 0 Ring finger domain WD40 PF00400.32 PSC74135.1 - 2.6e-23 81.9 2.2 0.00011 22.9 0.0 5.9 5 1 0 5 5 5 5 WD domain, G-beta repeat Nup160 PF11715.8 PSC74135.1 - 3.5e-05 22.6 0.0 0.0025 16.5 0.0 2.7 2 1 0 3 3 3 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 PSC74135.1 - 0.014 15.7 0.1 2.7 8.3 0.0 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain TFIIA PF03153.13 PSC74135.1 - 1.1 9.1 26.2 1.8 8.5 26.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2486 PF10667.9 PSC74135.1 - 4.3 7.5 33.6 7 6.8 33.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2486) Roughex PF06020.11 PSC74135.1 - 5 6.1 12.8 8 5.5 12.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DEC-1_N PF04625.13 PSC74137.1 - 0.3 10.1 4.7 0.34 9.9 4.7 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region DEC-1_N PF04625.13 PSC74138.1 - 0.3 10.1 4.7 0.34 9.9 4.7 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region HlyIII PF03006.20 PSC74139.1 - 9.7e-06 25.5 9.4 5.4e-05 23.0 9.4 1.9 1 1 0 1 1 1 1 Haemolysin-III related Mago_nashi PF02792.14 PSC74140.1 - 5.8e-74 246.9 0.1 9.7e-74 246.2 0.1 1.4 1 0 0 1 1 1 1 Mago nashi protein PAT1 PF09770.9 PSC74140.1 - 0.72 8.1 13.7 1.2 7.3 13.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Roughex PF06020.11 PSC74140.1 - 1.7 7.7 12.5 3.2 6.7 12.5 1.4 1 0 0 1 1 1 0 Drosophila roughex protein CDC45 PF02724.14 PSC74140.1 - 7 4.8 5.6 14 3.9 5.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Aa_trans PF01490.18 PSC74141.1 - 1.4e-30 106.4 4.4 2.2e-30 105.7 4.4 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein SUIM_assoc PF16619.5 PSC74141.1 - 0.0046 17.0 0.5 0.01 15.9 0.5 1.6 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 SMC_N PF02463.19 PSC74142.1 - 2.2e-68 230.0 0.4 2.9e-68 229.6 0.4 1.1 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 PSC74142.1 - 2.2e-21 76.3 0.1 2.2e-21 76.3 0.1 2.8 3 0 0 3 3 3 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.6 PSC74142.1 - 6.6e-11 42.6 0.1 0.00035 20.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 PSC74142.1 - 1.1e-07 32.6 22.6 1.1e-07 32.6 22.6 5.9 2 2 0 3 3 3 1 AAA domain AAA_15 PF13175.6 PSC74142.1 - 4.7e-07 29.9 0.1 4.7e-07 29.9 0.1 3.8 2 2 0 3 3 3 1 AAA ATPase domain ABC_tran PF00005.27 PSC74142.1 - 3e-05 24.5 9.7 0.0029 18.1 0.0 4.3 4 2 0 4 4 4 2 ABC transporter AAA_29 PF13555.6 PSC74142.1 - 0.0002 21.0 0.0 0.00051 19.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain HMMR_N PF15905.5 PSC74142.1 - 0.0011 18.6 8.1 0.0011 18.6 8.1 5.0 3 2 1 4 4 4 1 Hyaluronan mediated motility receptor N-terminal NPV_P10 PF05531.12 PSC74142.1 - 0.17 12.4 16.1 0.064 13.7 1.0 5.5 4 2 0 5 5 5 0 Nucleopolyhedrovirus P10 protein Tup_N PF08581.10 PSC74142.1 - 0.17 12.2 2.7 0.48 10.8 0.2 3.2 2 0 0 2 2 2 0 Tup N-terminal DEAD PF00270.29 PSC74143.1 - 2.4e-36 125.2 0.1 5.7e-36 123.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC74143.1 - 1.3e-28 99.6 0.2 2.3e-26 92.3 0.1 2.5 2 1 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.15 PSC74143.1 - 5.6e-07 29.7 0.0 1.2e-06 28.6 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit MoaE PF02391.17 PSC74143.1 - 0.14 12.4 0.1 0.48 10.7 0.1 1.9 1 0 0 1 1 1 0 MoaE protein Bac_surface_Ag PF01103.23 PSC74144.1 - 4.2e-30 105.3 0.0 5.6e-30 105.0 0.0 1.0 1 0 0 1 1 1 1 Surface antigen RIBIOP_C PF04950.12 PSC74145.1 - 3e-104 348.6 0.0 5.6e-104 347.7 0.0 1.4 1 0 0 1 1 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 PSC74145.1 - 5.5e-16 58.4 0.0 1.1e-15 57.5 0.0 1.5 1 0 0 1 1 1 1 AARP2CN (NUC121) domain PHD PF00628.29 PSC74145.1 - 4.8e-08 32.8 23.1 9.3e-05 22.2 0.3 3.6 3 0 0 3 3 3 3 PHD-finger zf-HC5HC2H PF13771.6 PSC74145.1 - 0.37 11.1 24.2 0.34 11.2 6.4 3.4 2 1 1 3 3 3 0 PHD-like zinc-binding domain SHNi-TPR PF10516.9 PSC74146.1 - 5.5e-06 25.7 0.4 1.5e-05 24.4 0.4 1.8 1 0 0 1 1 1 1 SHNi-TPR TPR_2 PF07719.17 PSC74146.1 - 0.002 18.1 5.4 1.3 9.3 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 PSC74146.1 - 0.0087 16.3 3.8 0.32 11.3 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Sec34 PF04136.15 PSC74146.1 - 0.017 15.0 0.4 0.36 10.7 0.0 2.2 2 0 0 2 2 2 0 Sec34-like family TBCC_N PF16752.5 PSC74146.1 - 0.027 14.9 3.6 3.6 8.1 0.9 2.5 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain zf-CpG_bind_C PF12269.8 PSC74146.1 - 0.23 11.2 0.8 0.67 9.7 0.7 1.7 2 0 0 2 2 2 0 CpG binding protein zinc finger C terminal domain TPR_14 PF13428.6 PSC74146.1 - 1 10.3 11.0 2.4 9.2 0.0 4.5 3 1 0 3 3 3 0 Tetratricopeptide repeat DUF4200 PF13863.6 PSC74146.1 - 1.4 9.3 7.7 0.56 10.6 3.4 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4200) NAD_binding_1 PF00175.21 PSC74147.1 - 0.014 16.1 0.0 0.061 14.0 0.0 2.2 2 1 0 2 2 2 0 Oxidoreductase NAD-binding domain DEAD PF00270.29 PSC74148.1 - 2.9e-49 167.2 0.0 4.8e-49 166.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC74148.1 - 1.4e-26 93.0 0.0 4.6e-26 91.3 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain rve PF00665.26 PSC74148.1 - 1.2e-18 67.4 0.0 4e-18 65.7 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain ResIII PF04851.15 PSC74148.1 - 0.00013 22.0 0.0 0.00024 21.1 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit rve_3 PF13683.6 PSC74148.1 - 0.0075 16.0 0.0 0.022 14.5 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Peroxin-22 PF12827.7 PSC74149.1 - 0.083 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis protein family DUF2892 PF11127.8 PSC74149.1 - 1.1 9.3 5.0 0.21 11.7 0.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2892) Ribosomal_60s PF00428.19 PSC74149.1 - 8 7.1 15.7 0.73 10.5 4.1 2.5 2 0 0 2 2 2 0 60s Acidic ribosomal protein Peptidase_C1 PF00112.23 PSC74150.1 - 8.8e-52 176.3 0.0 1.4e-51 175.7 0.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PSC74150.1 - 9.9e-13 48.3 1.4 1.4e-12 47.8 1.4 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PSC74150.1 - 3e-05 23.0 0.2 0.0024 16.7 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Cation_efflux PF01545.21 PSC74152.1 - 7.6e-29 100.9 2.6 1e-28 100.4 2.6 1.1 1 0 0 1 1 1 1 Cation efflux family S6PP PF05116.13 PSC74153.1 - 0.00018 21.1 0.0 0.0014 18.2 0.0 2.2 3 0 0 3 3 3 1 Sucrose-6F-phosphate phosphohydrolase Hydrolase_3 PF08282.12 PSC74153.1 - 0.02 14.7 0.0 0.13 12.0 0.0 2.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase zf-C3HC4_3 PF13920.6 PSC74154.1 - 4.5e-11 42.4 9.6 7.7e-11 41.7 9.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC74154.1 - 0.00019 21.3 10.7 0.00031 20.6 10.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC74154.1 - 0.00023 21.5 10.5 0.00037 20.8 10.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PSC74154.1 - 0.00037 20.3 12.5 0.00062 19.6 12.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PSC74154.1 - 0.15 12.0 10.0 0.26 11.2 10.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PSC74154.1 - 0.15 12.1 6.6 0.29 11.2 6.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger DUF1610 PF07754.11 PSC74154.1 - 0.19 11.7 0.9 0.65 10.0 0.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) zf-RING_5 PF14634.6 PSC74154.1 - 0.19 11.7 10.7 0.35 10.9 10.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PSC74154.1 - 1.2 9.3 9.7 2.1 8.6 9.7 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 PSC74154.1 - 2.7 7.8 11.5 1 9.2 8.6 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 PSC74154.1 - 4.2 7.3 5.7 7.8 6.4 5.7 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.6 PSC74155.1 - 4.5e-11 42.4 9.6 7.7e-11 41.7 9.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC74155.1 - 0.00019 21.3 10.7 0.00031 20.6 10.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC74155.1 - 0.00023 21.5 10.5 0.00037 20.8 10.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PSC74155.1 - 0.00037 20.3 12.5 0.00062 19.6 12.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PSC74155.1 - 0.15 12.0 10.0 0.26 11.2 10.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PSC74155.1 - 0.15 12.1 6.6 0.29 11.2 6.6 1.5 1 0 0 1 1 1 0 RING-type zinc-finger DUF1610 PF07754.11 PSC74155.1 - 0.19 11.7 0.9 0.65 10.0 0.9 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1610) zf-RING_5 PF14634.6 PSC74155.1 - 0.19 11.7 10.7 0.35 10.9 10.7 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PSC74155.1 - 1.2 9.3 9.7 2.1 8.6 9.7 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 PSC74155.1 - 2.7 7.8 11.5 1 9.2 8.6 1.7 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 PSC74155.1 - 4.2 7.3 5.7 7.8 6.4 5.7 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein LON_substr_bdg PF02190.16 PSC74156.1 - 6.5e-19 68.6 0.0 9.5e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 PSC74156.1 - 7.2e-11 41.7 12.1 1.3e-10 40.9 12.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC74156.1 - 4.7e-09 36.0 7.6 7.7e-09 35.3 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC74156.1 - 2.3e-07 31.0 10.3 4.1e-07 30.2 10.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PSC74156.1 - 2.6e-06 27.2 11.0 4.5e-06 26.4 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC74156.1 - 5e-06 26.4 9.1 8.8e-06 25.6 9.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PSC74156.1 - 5.4e-06 26.3 10.0 9.4e-06 25.5 10.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PSC74156.1 - 9.8e-06 25.3 8.4 1.8e-05 24.5 8.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 PSC74156.1 - 5.8e-05 23.1 5.3 0.00012 22.2 5.3 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 PSC74156.1 - 6.7e-05 23.0 10.2 0.00012 22.1 10.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 PSC74156.1 - 0.00039 20.2 6.8 0.00078 19.2 6.8 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 PSC74156.1 - 0.012 15.9 5.1 0.024 14.9 5.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain TPR_1 PF00515.28 PSC74156.1 - 0.037 13.8 0.2 0.12 12.2 0.2 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat zf-RING_6 PF14835.6 PSC74156.1 - 0.067 13.1 3.4 0.13 12.2 3.4 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1272 PF06906.11 PSC74156.1 - 0.43 10.7 5.7 1 9.5 5.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-UDP PF14569.6 PSC74156.1 - 1.6 8.9 4.5 1.1 9.5 2.1 1.9 2 0 0 2 2 2 0 Zinc-binding RING-finger LON_substr_bdg PF02190.16 PSC74157.1 - 6.6e-19 68.6 0.0 9.5e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain zf-C3HC4_2 PF13923.6 PSC74157.1 - 7.2e-11 41.7 12.1 1.3e-10 40.9 12.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC74157.1 - 4.7e-09 36.0 7.6 7.7e-09 35.3 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC74157.1 - 2.3e-07 31.0 10.3 4.1e-07 30.2 10.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PSC74157.1 - 2.6e-06 27.2 11.0 4.5e-06 26.4 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC74157.1 - 5e-06 26.4 9.1 8.8e-06 25.7 9.1 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PSC74157.1 - 5.4e-06 26.3 10.0 9.3e-06 25.5 10.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PSC74157.1 - 9.8e-06 25.3 8.4 1.8e-05 24.5 8.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 PSC74157.1 - 5.9e-05 23.1 5.3 0.00012 22.2 5.3 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 PSC74157.1 - 6.7e-05 23.0 10.2 0.00012 22.1 10.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 PSC74157.1 - 0.00039 20.2 6.8 0.00077 19.2 6.8 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain TPR_1 PF00515.28 PSC74157.1 - 0.0068 16.2 0.7 0.12 12.2 0.2 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-rbx1 PF12678.7 PSC74157.1 - 0.012 15.9 5.1 0.024 14.9 5.1 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 PSC74157.1 - 0.067 13.1 3.4 0.13 12.2 3.4 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TPR_2 PF07719.17 PSC74157.1 - 0.094 12.9 8.3 0.57 10.4 0.7 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1272 PF06906.11 PSC74157.1 - 0.43 10.7 5.7 1 9.5 5.7 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-UDP PF14569.6 PSC74157.1 - 1.6 8.9 4.5 1.1 9.5 2.1 1.9 2 0 0 2 2 2 0 Zinc-binding RING-finger Chloroa_b-bind PF00504.21 PSC74158.1 - 7.3e-48 163.1 0.0 1.1e-47 162.5 0.0 1.3 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Ank_4 PF13637.6 PSC74159.1 - 1.5e-09 38.2 0.2 9.5e-08 32.4 0.1 2.7 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC74159.1 - 4.8e-09 35.7 0.1 0.0064 16.9 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 PSC74159.1 - 1.8e-07 31.6 0.0 4.5e-07 30.4 0.0 1.7 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 PSC74159.1 - 2.4e-07 30.9 0.1 0.03 14.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 PSC74159.1 - 5.1e-05 23.5 0.0 0.00055 20.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Peptidase_M11 PF05548.11 PSC74160.1 - 4.5e-25 88.4 0.3 9.1e-25 87.5 0.3 1.4 1 0 0 1 1 1 1 Gametolysin peptidase M11 zf-C2H2_4 PF13894.6 PSC74160.1 - 2.8e-09 37.0 8.9 0.013 16.3 0.1 4.4 4 0 0 4 4 4 3 C2H2-type zinc finger zf-C2H2 PF00096.26 PSC74160.1 - 1.8e-07 31.3 6.4 0.24 11.9 0.0 4.2 4 0 0 4 4 4 3 Zinc finger, C2H2 type zf-C2H2_6 PF13912.6 PSC74160.1 - 8.3e-05 22.5 0.8 0.03 14.3 0.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_11 PF16622.5 PSC74160.1 - 0.0083 15.9 0.0 3.8 7.4 0.1 2.9 2 0 0 2 2 2 2 zinc-finger C2H2-type Reprolysin_4 PF13583.6 PSC74160.1 - 0.0097 15.6 0.4 0.035 13.8 0.2 2.0 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Peptidase_M66 PF10462.9 PSC74160.1 - 0.2 10.6 0.6 0.33 9.9 0.6 1.2 1 0 0 1 1 1 0 Peptidase M66 MACPF PF01823.19 PSC74162.1 - 8.6e-10 39.1 0.1 1.7e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 MAC/Perforin domain Gal_Lectin PF02140.18 PSC74162.1 - 0.00012 22.4 0.5 0.0017 18.8 0.0 2.8 2 1 0 2 2 2 1 Galactose binding lectin domain Nucleotid_trans PF03407.16 PSC74163.1 - 4.4e-11 43.2 0.0 6.9e-11 42.5 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase MORN PF02493.20 PSC74163.1 - 1.3e-09 37.4 4.7 0.015 15.1 0.3 3.9 3 0 0 3 3 3 3 MORN repeat Ribosomal_60s PF00428.19 PSC74163.1 - 0.45 11.1 2.2 1.1 9.9 2.2 1.6 1 0 0 1 1 1 0 60s Acidic ribosomal protein TPT PF03151.16 PSC74164.1 - 8.3e-17 61.5 17.8 1.2e-16 60.9 17.8 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PSC74164.1 - 3.2e-14 53.2 21.9 5.1e-09 36.4 6.5 3.0 2 1 1 3 3 3 2 EamA-like transporter family Pectate_lyase_3 PF12708.7 PSC74164.1 - 2e-10 40.9 2.8 1.2e-09 38.4 0.3 2.6 2 1 1 3 3 3 1 Pectate lyase superfamily protein Gal_Lectin PF02140.18 PSC74164.1 - 1.7e-08 34.8 0.1 4e-08 33.6 0.1 1.7 1 0 0 1 1 1 1 Galactose binding lectin domain UAA PF08449.11 PSC74164.1 - 3.8e-06 26.3 20.5 6.3e-06 25.6 18.7 2.1 1 1 1 2 2 2 1 UAA transporter family Beta_helix PF13229.6 PSC74164.1 - 0.0019 18.0 2.2 0.0036 17.2 2.2 1.3 1 0 0 1 1 1 1 Right handed beta helix region End_N_terminal PF12218.8 PSC74164.1 - 0.013 15.2 0.2 0.029 14.1 0.2 1.6 1 0 0 1 1 1 0 N terminal extension of bacteriophage endosialidase Chitin_bind_1 PF00187.19 PSC74164.1 - 0.018 15.5 17.0 0.018 15.5 14.8 2.1 2 0 0 2 2 2 0 Chitin recognition protein AAA_5 PF07728.14 PSC74164.1 - 0.046 13.7 0.6 0.079 13.0 0.6 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ephrin_rec_like PF07699.13 PSC74165.1 - 0.00013 21.6 5.2 0.00013 21.6 5.2 3.1 1 1 2 3 3 3 2 Putative ephrin-receptor like Cadherin-like PF12733.7 PSC74165.1 - 0.0033 17.9 0.0 0.014 15.9 0.0 2.1 1 1 0 1 1 1 1 Cadherin-like beta sandwich domain Pkinase_Tyr PF07714.17 PSC74167.1 - 2.6e-42 144.9 0.0 4.8e-42 144.0 0.0 1.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC74167.1 - 2e-33 115.9 0.0 2.8e-33 115.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 PSC74167.1 - 0.00025 21.0 1.0 0.00025 21.0 1.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PSC74167.1 - 0.0069 15.4 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_Tyr PF07714.17 PSC74168.1 - 7.2e-39 133.6 0.0 4.1e-38 131.1 0.0 2.4 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC74168.1 - 3.2e-29 102.1 0.0 9e-29 100.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.23 PSC74168.1 - 0.0058 16.6 0.8 0.011 15.6 0.1 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PSC74168.1 - 0.016 14.2 0.0 0.069 12.1 0.0 1.8 2 0 0 2 2 2 0 Haspin like kinase domain zf-RING_2 PF13639.6 PSC74169.1 - 4.8e-08 33.2 6.5 4.8e-08 33.2 6.5 1.7 2 0 0 2 2 1 1 Ring finger domain zf-RING_4 PF14570.6 PSC74169.1 - 1.3e-05 24.8 4.8 2.4e-05 24.0 4.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 PSC74169.1 - 0.00019 21.4 2.4 0.00036 20.5 2.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PSC74169.1 - 0.00061 19.7 4.9 0.00061 19.7 4.9 1.7 2 0 0 2 2 1 1 zinc-RING finger domain RINGv PF12906.7 PSC74169.1 - 0.0015 18.6 9.1 0.0027 17.8 9.1 1.4 1 0 0 1 1 1 1 RING-variant domain Prok-RING_1 PF14446.6 PSC74169.1 - 0.0017 18.2 6.7 0.0018 18.1 1.9 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 SWIM PF04434.17 PSC74169.1 - 0.0018 17.9 2.4 0.0038 16.8 2.4 1.6 1 0 0 1 1 1 1 SWIM zinc finger zf-rbx1 PF12678.7 PSC74169.1 - 0.0023 18.2 4.6 0.005 17.1 4.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PSC74169.1 - 0.0038 17.1 5.7 0.0038 17.1 5.7 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PSC74169.1 - 0.0082 16.2 2.4 0.0082 16.2 2.4 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 PSC74169.1 - 0.016 15.3 3.9 0.016 15.3 3.9 2.0 2 0 0 2 2 2 0 FANCL C-terminal domain PHD PF00628.29 PSC74169.1 - 0.019 14.9 7.1 0.019 14.9 7.1 1.6 2 0 0 2 2 1 0 PHD-finger zf-C3HC4_2 PF13923.6 PSC74169.1 - 0.089 12.6 6.3 0.28 11.1 6.3 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RskA PF10099.9 PSC74169.1 - 0.23 11.7 14.9 0.086 13.1 6.3 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA zf-UDP PF14569.6 PSC74169.1 - 0.24 11.5 2.7 0.25 11.5 0.9 1.8 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-Di19 PF05605.12 PSC74169.1 - 0.91 9.9 4.5 2.8 8.3 0.7 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_3 PF13920.6 PSC74169.1 - 6.6 6.7 12.6 0.036 13.9 3.6 1.9 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) Tmpp129 PF10272.9 PSC74169.1 - 9.9 5.3 6.9 14 4.9 6.9 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor zf-RING_2 PF13639.6 PSC74170.1 - 4.8e-08 33.2 6.5 4.8e-08 33.2 6.5 1.8 2 0 0 2 2 2 1 Ring finger domain zf-RING_4 PF14570.6 PSC74170.1 - 1.3e-05 24.9 4.8 2.4e-05 24.0 4.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 PSC74170.1 - 0.00019 21.4 2.4 0.00036 20.5 2.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 PSC74170.1 - 0.00061 19.7 4.9 0.00061 19.7 4.9 1.7 2 0 0 2 2 1 1 zinc-RING finger domain RINGv PF12906.7 PSC74170.1 - 0.0015 18.6 9.1 0.0026 17.8 9.1 1.4 1 0 0 1 1 1 1 RING-variant domain Prok-RING_1 PF14446.6 PSC74170.1 - 0.0017 18.3 6.7 0.0018 18.2 1.9 2.3 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 zf-rbx1 PF12678.7 PSC74170.1 - 0.0023 18.2 4.6 0.0049 17.1 4.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PSC74170.1 - 0.0037 17.1 5.7 0.0037 17.1 5.7 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) SWIM PF04434.17 PSC74170.1 - 0.0051 16.4 1.4 0.011 15.4 1.4 1.6 1 0 0 1 1 1 1 SWIM zinc finger zf-ANAPC11 PF12861.7 PSC74170.1 - 0.0081 16.2 2.4 0.0081 16.2 2.4 1.8 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 PSC74170.1 - 0.016 15.4 3.9 0.016 15.4 3.9 1.7 2 0 0 2 2 1 0 FANCL C-terminal domain PHD PF00628.29 PSC74170.1 - 0.019 14.9 7.1 0.019 14.9 7.1 1.6 2 0 0 2 2 1 0 PHD-finger zf-C3HC4_2 PF13923.6 PSC74170.1 - 0.088 12.7 6.3 0.27 11.1 6.3 1.9 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RskA PF10099.9 PSC74170.1 - 0.23 11.7 14.8 0.09 13.1 6.2 2.3 2 0 0 2 2 2 0 Anti-sigma-K factor rskA zf-UDP PF14569.6 PSC74170.1 - 0.25 11.5 2.7 0.24 11.5 0.9 1.8 2 0 0 2 2 2 0 Zinc-binding RING-finger zf-Di19 PF05605.12 PSC74170.1 - 0.9 9.9 4.5 2.8 8.3 0.7 2.4 1 1 1 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_3 PF13920.6 PSC74170.1 - 6.6 6.7 12.6 0.035 14.0 3.6 1.8 2 0 0 2 2 1 0 Zinc finger, C3HC4 type (RING finger) Tmpp129 PF10272.9 PSC74170.1 - 9.9 5.4 6.9 14 4.9 6.9 1.1 1 0 0 1 1 1 0 Putative transmembrane protein precursor RRM_1 PF00076.22 PSC74171.1 - 7.6e-34 115.4 0.0 2e-11 43.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PSC74171.1 - 0.0017 18.4 0.0 1.4 9.1 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 PSC74171.1 - 0.24 11.5 0.0 0.24 11.5 0.0 3.3 4 0 0 4 4 4 0 RNA binding motif RRM_1 PF00076.22 PSC74172.1 - 2.9e-36 123.1 0.0 3e-13 49.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PSC74172.1 - 0.0038 17.3 0.0 1.4 9.1 0.0 3.2 3 0 0 3 3 3 1 RNA recognition motif RRM_3 PF08777.11 PSC74172.1 - 0.24 11.5 0.0 0.24 11.5 0.0 3.6 4 0 0 4 4 4 0 RNA binding motif DBC1 PF14443.6 PSC74173.1 - 2.8e-29 101.6 0.0 6.3e-29 100.5 0.0 1.6 1 0 0 1 1 1 1 DBC1 SAP PF02037.27 PSC74173.1 - 0.0003 20.5 0.0 0.00056 19.6 0.0 1.5 1 0 0 1 1 1 1 SAP domain BUD22 PF09073.10 PSC74173.1 - 1.3 8.2 42.0 0.31 10.3 16.4 2.7 2 0 0 2 2 2 0 BUD22 DBC1 PF14443.6 PSC74174.1 - 2.8e-29 101.6 0.0 6.3e-29 100.5 0.0 1.6 1 0 0 1 1 1 1 DBC1 SAP PF02037.27 PSC74174.1 - 0.0003 20.5 0.0 0.00056 19.6 0.0 1.5 1 0 0 1 1 1 1 SAP domain BUD22 PF09073.10 PSC74174.1 - 1.3 8.3 42.0 0.31 10.3 16.4 2.7 2 0 0 2 2 2 0 BUD22 PIG-L PF02585.17 PSC74175.1 - 6.2e-18 65.7 0.1 1.2e-17 64.8 0.1 1.5 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glucosamine_iso PF01182.20 PSC74175.1 - 2e-11 44.2 0.0 4.8e-11 43.0 0.0 1.6 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Gly_kinase PF02595.15 PSC74175.1 - 6.9 5.6 6.8 0.68 8.9 0.0 2.4 3 0 0 3 3 3 0 Glycerate kinase family PIG-L PF02585.17 PSC74176.1 - 6.4e-18 65.7 0.1 1.2e-17 64.7 0.1 1.5 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glucosamine_iso PF01182.20 PSC74176.1 - 5.7e-10 39.5 0.0 1.3e-09 38.2 0.0 1.6 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Gly_kinase PF02595.15 PSC74176.1 - 7 5.5 6.8 0.69 8.8 0.0 2.4 3 0 0 3 3 3 0 Glycerate kinase family Collagen PF01391.18 PSC74177.1 - 2.6e-10 39.9 19.0 4.3e-10 39.2 19.0 1.3 1 0 0 1 1 1 1 Collagen triple helix repeat (20 copies) CAF1 PF04857.20 PSC74178.1 - 3.3e-56 190.8 0.0 4.1e-56 190.5 0.0 1.1 1 0 0 1 1 1 1 CAF1 family ribonuclease SNF2_N PF00176.23 PSC74179.1 - 2e-58 197.8 0.2 2e-58 197.8 0.2 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC74179.1 - 1.6e-15 57.4 0.0 5.9e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 PSC74179.1 - 1.1e-13 50.9 0.5 2.5e-09 36.9 0.0 3.3 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DUF1086 PF06461.11 PSC74179.1 - 5.2e-10 39.3 0.0 1.3e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) PHD PF00628.29 PSC74179.1 - 3.1e-07 30.2 1.1 5.8e-07 29.3 1.1 1.5 1 0 0 1 1 1 1 PHD-finger DnaJ PF00226.31 PSC74179.1 - 2.6e-06 27.5 0.1 5.9e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Zf_RING PF16744.5 PSC74179.1 - 0.0065 16.6 0.5 0.016 15.3 0.5 1.6 1 0 0 1 1 1 1 KIAA1045 RING finger CHDCT2 PF08074.11 PSC74179.1 - 0.03 14.5 0.0 0.03 14.5 0.0 4.1 4 1 0 4 4 4 0 CHDCT2 (NUC038) domain zf-rbx1 PF12678.7 PSC74179.1 - 0.72 10.2 2.3 1.7 9.0 2.3 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain SNF2_N PF00176.23 PSC74180.1 - 2e-58 197.8 0.2 2e-58 197.8 0.2 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC74180.1 - 1.7e-15 57.4 0.0 5.9e-15 55.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 PSC74180.1 - 1.1e-13 50.9 0.5 2.5e-09 36.9 0.0 3.3 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DUF1086 PF06461.11 PSC74180.1 - 1.4e-10 41.1 0.0 3.5e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1086) PHD PF00628.29 PSC74180.1 - 3.1e-07 30.2 1.1 5.8e-07 29.3 1.1 1.5 1 0 0 1 1 1 1 PHD-finger DnaJ PF00226.31 PSC74180.1 - 2.6e-06 27.5 0.1 5.9e-06 26.3 0.1 1.6 1 0 0 1 1 1 1 DnaJ domain Zf_RING PF16744.5 PSC74180.1 - 0.0065 16.5 0.5 0.016 15.3 0.5 1.6 1 0 0 1 1 1 1 KIAA1045 RING finger CHDCT2 PF08074.11 PSC74180.1 - 0.03 14.5 0.0 0.03 14.5 0.0 4.1 4 1 0 4 4 4 0 CHDCT2 (NUC038) domain zf-rbx1 PF12678.7 PSC74180.1 - 0.72 10.2 2.3 1.7 9.0 2.3 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger domain Abhydrolase_1 PF00561.20 PSC74181.1 - 1.1e-18 67.8 0.0 6.5e-17 62.0 0.0 3.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC74181.1 - 2.3e-15 56.5 4.6 8.7e-08 31.7 0.1 3.5 3 0 0 3 3 3 3 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PSC74181.1 - 8.1e-11 42.9 25.3 3.2e-07 31.2 13.8 6.2 3 3 0 4 4 2 2 Alpha/beta hydrolase family Ser_hydrolase PF06821.13 PSC74181.1 - 9.2e-06 25.6 0.3 0.001 19.0 0.2 2.7 2 0 0 2 2 2 1 Serine hydrolase Abhydrolase_4 PF08386.10 PSC74181.1 - 0.00073 19.6 0.0 0.0019 18.2 0.0 1.7 1 0 0 1 1 1 1 TAP-like protein FSH1 PF03959.13 PSC74181.1 - 0.001 18.8 0.7 0.039 13.6 0.0 2.5 2 1 0 2 2 2 1 Serine hydrolase (FSH1) START PF01852.19 PSC74181.1 - 0.0012 18.2 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 START domain Abhydrolase_9 PF10081.9 PSC74181.1 - 0.034 13.2 0.1 0.06 12.4 0.1 1.3 1 0 0 1 1 1 0 Alpha/beta-hydrolase family Abhydrolase_5 PF12695.7 PSC74181.1 - 0.048 13.4 0.0 1.6 8.5 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 PSC74181.1 - 0.084 12.3 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 PSC74181.1 - 0.17 11.7 0.2 16 5.2 0.0 2.9 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase TFIIA PF03153.13 PSC74181.1 - 6.2 6.7 7.1 10 6.0 7.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit UPF0160 PF03690.13 PSC74182.1 - 7.4e-133 443.1 0.0 1e-132 442.6 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) MutS_V PF00488.21 PSC74182.1 - 4.6e-25 88.8 0.0 7.9e-25 88.0 0.0 1.3 1 0 0 1 1 1 1 MutS domain V AAA_23 PF13476.6 PSC74182.1 - 0.1 13.1 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain Atg14 PF10186.9 PSC74183.1 - 3.3e-07 29.7 2.0 1.4e-06 27.6 2.1 1.7 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 VPS38 PF17649.1 PSC74183.1 - 0.00089 18.2 0.0 0.0012 17.8 0.0 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting 38 MFS18 PF17352.2 PSC74183.1 - 0.006 16.9 0.1 0.006 16.9 0.1 2.7 4 0 0 4 4 4 1 Male Flower Specific protein 18 SNAP PF14938.6 PSC74185.1 - 2.3e-102 342.2 20.0 2.6e-102 342.0 20.0 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 PSC74185.1 - 1e-06 28.9 13.9 0.027 14.7 0.4 4.5 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 PSC74185.1 - 8.5e-06 25.5 5.4 2 8.7 0.1 5.2 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 PSC74185.1 - 7.8e-05 22.6 10.4 0.082 13.2 0.2 5.5 3 1 3 6 6 6 2 Tetratricopeptide repeat Ala_racemase_N PF01168.20 PSC74185.1 - 0.00012 21.9 2.7 0.00023 20.9 2.7 1.4 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain TPR_1 PF00515.28 PSC74185.1 - 0.00056 19.6 6.1 1.5 8.8 0.3 4.7 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 PSC74185.1 - 0.00074 19.4 12.1 1.9 8.8 0.8 5.7 5 0 0 5 5 5 2 Tetratricopeptide repeat Sel1 PF08238.12 PSC74185.1 - 0.0028 18.3 3.1 4.5 8.1 0.1 3.7 3 0 0 3 3 3 1 Sel1 repeat TPR_6 PF13174.6 PSC74185.1 - 0.0071 16.9 15.9 12 6.8 0.1 6.1 6 1 1 7 7 6 0 Tetratricopeptide repeat MIT PF04212.18 PSC74185.1 - 0.0092 16.0 12.8 0.49 10.5 2.1 3.9 3 2 1 4 4 4 2 MIT (microtubule interacting and transport) domain NSF PF02071.20 PSC74185.1 - 0.057 14.1 19.4 3.9 8.7 0.0 6.5 5 1 1 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_16 PF13432.6 PSC74185.1 - 0.06 14.0 17.4 1.1 9.9 2.2 4.5 3 3 1 4 4 4 0 Tetratricopeptide repeat DHR-2 PF06920.13 PSC74185.1 - 0.17 10.5 2.9 3.9 6.0 0.2 2.2 1 1 1 2 2 2 0 Dock homology region 2 CdiI_2 PF18593.1 PSC74185.1 - 0.48 11.1 2.7 11 6.8 0.1 3.0 2 2 1 3 3 3 0 CdiI immunity protein LPD5 PF18799.1 PSC74185.1 - 0.73 10.2 4.0 0.37 11.2 1.2 1.9 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 5 Mad3_BUB1_I PF08311.12 PSC74185.1 - 0.73 9.8 3.6 15 5.6 0.3 2.6 2 1 0 2 2 2 0 Mad3/BUB1 homology region 1 ANAPC3 PF12895.7 PSC74185.1 - 0.85 9.9 6.5 0.84 9.9 0.3 2.8 1 1 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 HHH_8 PF14716.6 PSC74185.1 - 0.97 9.8 7.5 2 8.8 0.2 3.2 3 0 0 3 3 3 0 Helix-hairpin-helix domain Spatacsin_C PF14649.6 PSC74185.1 - 3.7 6.6 11.2 6.9e+02 -0.9 11.2 2.3 1 1 0 1 1 1 0 Spatacsin C-terminus TPR_11 PF13414.6 PSC74185.1 - 4 7.2 8.6 5 6.9 1.4 4.2 5 1 0 5 5 5 0 TPR repeat Trp_Tyr_perm PF03222.13 PSC74187.1 - 3.9e-44 151.3 24.4 9.8e-32 110.5 12.6 3.0 2 1 0 2 2 2 2 Tryptophan/tyrosine permease family Aa_trans PF01490.18 PSC74187.1 - 0.59 8.8 8.6 0.15 10.8 5.1 1.8 2 0 0 2 2 2 0 Transmembrane amino acid transporter protein fn3 PF00041.21 PSC74188.1 - 0.0016 18.8 0.2 22 5.5 0.1 4.2 4 1 0 4 4 4 3 Fibronectin type III domain AAA PF00004.29 PSC74189.1 - 7.3e-42 142.9 0.0 1.2e-41 142.3 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PSC74189.1 - 1e-10 41.2 1.1 3e-10 39.7 1.1 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 PSC74189.1 - 4.4e-07 30.4 0.3 0.0006 20.2 0.2 3.0 1 1 1 2 2 2 2 AAA ATPase domain FtsH_ext PF06480.15 PSC74189.1 - 5.9e-05 23.4 1.6 0.00045 20.5 0.1 2.9 2 1 0 2 2 2 1 FtsH Extracellular TIP49 PF06068.13 PSC74189.1 - 0.00015 21.1 0.1 0.00023 20.5 0.1 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 PSC74189.1 - 0.00052 19.8 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PSC74189.1 - 0.00062 19.8 0.0 0.0021 18.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PSC74189.1 - 0.0026 18.0 0.1 0.12 12.7 0.1 2.4 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.6 PSC74189.1 - 0.008 16.4 0.0 0.016 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 PSC74189.1 - 0.014 15.5 0.0 0.026 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) TsaE PF02367.17 PSC74189.1 - 0.016 15.2 0.0 0.027 14.5 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 PSC74189.1 - 0.018 15.2 0.0 0.033 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 PSC74189.1 - 0.022 14.5 0.0 0.04 13.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 PSC74189.1 - 0.026 13.9 0.1 0.052 12.9 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 PSC74189.1 - 0.033 13.9 0.0 0.063 13.0 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_25 PF13481.6 PSC74189.1 - 0.045 13.3 0.6 2 8.0 0.3 2.4 1 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 PSC74189.1 - 0.12 12.9 0.0 0.21 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PSC74189.1 - 0.3 10.6 0.0 0.86 9.1 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Pantoate_ligase PF02569.15 PSC74190.1 - 4.3e-95 317.9 0.0 4.9e-95 317.7 0.0 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase LAP1C PF05609.12 PSC74191.1 - 0.013 14.6 4.3 0.015 14.4 4.3 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DNA_pol_A PF00476.20 PSC74192.1 - 8.2e-102 341.1 0.0 1.1e-101 340.6 0.0 1.1 1 0 0 1 1 1 1 DNA polymerase family A CP12 PF02672.15 PSC74193.1 - 5.3 7.9 8.3 0.62 10.9 3.6 1.9 2 0 0 2 2 2 0 CP12 domain Ribosomal_60s PF00428.19 PSC74194.1 - 2.2e-26 92.2 10.5 2.6e-26 92.0 10.5 1.0 1 0 0 1 1 1 1 60s Acidic ribosomal protein YqfQ PF14181.6 PSC74194.1 - 0.052 13.7 0.3 0.067 13.4 0.3 1.2 1 0 0 1 1 1 0 YqfQ-like protein EzrA PF06160.12 PSC74195.1 - 0.00019 19.8 13.9 0.00019 19.8 13.9 1.9 3 0 0 3 3 3 1 Septation ring formation regulator, EzrA ERM PF00769.19 PSC74195.1 - 0.001 18.9 25.8 0.001 18.9 25.8 4.1 3 1 1 4 4 4 1 Ezrin/radixin/moesin family ATG16 PF08614.11 PSC74195.1 - 0.039 14.2 54.9 0.41 10.9 13.0 4.1 2 1 2 4 4 4 0 Autophagy protein 16 (ATG16) THOC7 PF05615.13 PSC74195.1 - 0.1 12.8 46.2 0.08 13.2 2.9 4.4 4 1 0 4 4 4 0 Tho complex subunit 7 PRKG1_interact PF15898.5 PSC74196.1 - 0.019 15.8 7.6 0.019 15.8 7.6 2.4 1 1 2 3 3 3 0 cGMP-dependent protein kinase interacting domain ABC_tran_CTD PF16326.5 PSC74196.1 - 0.024 14.9 3.5 0.024 14.9 3.5 3.5 1 1 2 3 3 3 0 ABC transporter C-terminal domain DUF812 PF05667.11 PSC74196.1 - 0.081 11.8 10.5 0.11 11.4 10.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) DUF16 PF01519.16 PSC74196.1 - 0.091 13.3 0.5 0.19 12.2 0.3 1.6 1 1 0 1 1 1 0 Protein of unknown function DUF16 FlxA PF14282.6 PSC74196.1 - 0.26 11.3 12.3 0.06 13.4 3.4 2.4 1 1 1 2 2 2 0 FlxA-like protein Uso1_p115_C PF04871.13 PSC74196.1 - 0.47 10.8 26.9 0.042 14.2 8.8 2.4 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF1664 PF07889.12 PSC74196.1 - 0.67 10.0 2.3 6.5 6.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Tropomyosin_1 PF12718.7 PSC74196.1 - 0.94 9.6 18.4 2.7 8.2 11.9 2.5 1 1 1 2 2 2 0 Tropomyosin like DUF2205 PF10224.9 PSC74196.1 - 0.96 9.5 6.1 0.4 10.7 1.2 2.6 2 1 0 2 2 2 0 Short coiled-coil protein ATG16 PF08614.11 PSC74196.1 - 2.2 8.4 32.7 2.6 8.2 14.2 2.6 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) DUF3450 PF11932.8 PSC74196.1 - 2.7 7.2 26.3 0.9 8.8 8.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) GAS PF13851.6 PSC74196.1 - 3.5 6.9 18.2 6.9 6.0 0.3 2.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Lzipper-MIP1 PF14389.6 PSC74196.1 - 3.8 7.9 11.6 1 9.7 3.7 3.2 2 2 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Jnk-SapK_ap_N PF09744.9 PSC74196.1 - 4.8 7.4 22.3 6.6 6.9 15.3 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 SMP_2 PF10144.9 PSC74196.1 - 4.9 6.8 9.9 1.1 9.0 4.8 2.0 2 0 0 2 2 2 0 Bacterial virulence factor haemolysin V_ATPase_I PF01496.19 PSC74196.1 - 5.5 4.8 5.9 7.5 4.3 5.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UPF0242 PF06785.11 PSC74196.1 - 8.2 6.5 11.1 10 6.1 6.5 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF4200 PF13863.6 PSC74196.1 - 8.8 6.8 19.4 1.8 9.0 6.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) AAA_13 PF13166.6 PSC74196.1 - 9.1 4.8 15.8 30 3.1 15.8 1.6 1 1 0 1 1 1 0 AAA domain TMF_TATA_bd PF12325.8 PSC74196.1 - 9.3 6.5 15.8 4.8 7.4 1.4 3.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 TATA binding ADP_ribosyl_GH PF03747.14 PSC74197.1 - 4.4e-49 167.8 0.8 5.3e-49 167.5 0.8 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase COesterase PF00135.28 PSC74197.1 - 0.22 10.3 0.0 0.3 9.9 0.0 1.1 1 0 0 1 1 1 0 Carboxylesterase family Gly-zipper_YMGG PF13441.6 PSC74197.1 - 2.4 8.0 14.2 1.6 8.5 1.5 3.0 3 0 0 3 3 3 0 YMGG-like Gly-zipper Usp PF00582.26 PSC74198.1 - 1.4e-19 71.0 0.1 2.2e-19 70.4 0.1 1.2 1 0 0 1 1 1 1 Universal stress protein family Gly_kinase PF02595.15 PSC74198.1 - 0.0081 15.2 0.9 0.011 14.8 0.1 1.5 1 1 1 2 2 2 1 Glycerate kinase family Tir_receptor_N PF07490.11 PSC74198.1 - 0.0099 15.7 0.1 0.013 15.4 0.1 1.2 1 0 0 1 1 1 1 Translocated intimin receptor (Tir) N-terminus baeRF_family10 PF18854.1 PSC74198.1 - 0.017 15.4 0.1 0.025 14.8 0.1 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 10 TfuA PF07812.12 PSC74198.1 - 0.095 12.4 0.7 0.2 11.4 0.7 1.5 1 0 0 1 1 1 0 TfuA-like protein rve PF00665.26 PSC74199.1 - 1.9e-18 66.7 0.0 4e-18 65.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Sulfotransfer_2 PF03567.14 PSC74199.1 - 0.00012 22.1 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family rve_3 PF13683.6 PSC74199.1 - 0.0091 15.8 0.1 0.037 13.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain rve PF00665.26 PSC74200.1 - 1.9e-18 66.8 0.0 3.9e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Sulfotransfer_2 PF03567.14 PSC74200.1 - 0.00013 21.9 0.0 0.00022 21.2 0.0 1.3 1 0 0 1 1 1 1 Sulfotransferase family rve_3 PF13683.6 PSC74200.1 - 0.0086 15.8 0.1 0.036 13.9 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain NADH-u_ox-rdase PF10785.9 PSC74201.1 - 6.8e-20 71.6 1.1 1.9e-19 70.1 0.1 2.4 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit LRR_6 PF13516.6 PSC74201.1 - 5.8e-06 25.9 0.8 0.0011 18.8 0.1 3.2 3 0 0 3 3 3 1 Leucine Rich repeat LRR_4 PF12799.7 PSC74201.1 - 0.024 15.0 0.4 0.061 13.8 0.4 1.7 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PSC74201.1 - 0.2 12.3 0.1 5.2 8.0 0.1 3.0 3 0 0 3 3 3 0 Leucine Rich Repeat SlyX PF04102.12 PSC74201.1 - 0.26 11.9 0.0 0.26 11.9 0.0 18.6 15 6 3 19 19 19 0 SlyX Fib_alpha PF08702.10 PSC74201.1 - 5.1 7.3 16.0 18 5.5 0.0 7.0 6 1 1 7 7 7 0 Fibrinogen alpha/beta chain family SpoVS PF04232.12 PSC74202.1 - 9e-35 118.3 0.0 1.4e-18 66.4 0.0 2.1 2 0 0 2 2 2 2 Stage V sporulation protein S (SpoVS) Beta_helix PF13229.6 PSC74203.1 - 3.2e-09 36.8 8.8 0.0015 18.4 0.4 3.4 3 1 0 3 3 3 2 Right handed beta helix region SUIM_assoc PF16619.5 PSC74203.1 - 0.22 11.6 5.9 0.087 12.9 2.6 2.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Chlam_PMP PF02415.17 PSC74203.1 - 6.3 7.5 41.7 7.7 7.2 0.1 10.3 10 0 0 10 10 10 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Spt20 PF12090.8 PSC74203.1 - 6.5 6.3 6.8 9.9 5.7 6.8 1.2 1 0 0 1 1 1 0 Spt20 family Lipase_3 PF01764.25 PSC74204.1 - 2e-22 79.6 0.0 4.8e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 PSC74204.1 - 0.022 14.8 0.9 0.064 13.3 0.0 2.2 2 0 0 2 2 2 0 Lipase 3 N-terminal region Lipase_3 PF01764.25 PSC74205.1 - 1.2e-22 80.3 0.0 2.9e-22 79.1 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Lipase3_N PF03893.16 PSC74205.1 - 0.021 14.9 0.8 0.064 13.3 0.0 2.2 2 0 0 2 2 2 0 Lipase 3 N-terminal region Abhydrolase_3 PF07859.13 PSC74205.1 - 0.03 14.2 0.0 0.063 13.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC74205.1 - 0.075 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Polysacc_deac_1 PF01522.21 PSC74206.1 - 1.5e-12 47.5 0.1 2.6e-12 46.7 0.1 1.4 1 0 0 1 1 1 1 Polysaccharide deacetylase Stig1 PF04885.13 PSC74207.1 - 3.8e-16 59.8 80.8 2.2e-06 28.2 17.6 4.4 2 2 2 4 4 4 4 Stigma-specific protein, Stig1 Cyclin_N PF00134.23 PSC74209.1 - 9.7e-08 31.8 1.2 3.7e-07 29.9 0.1 2.2 2 1 1 3 3 3 1 Cyclin, N-terminal domain Med4 PF10018.9 PSC74209.1 - 0.0002 21.1 0.9 0.00038 20.2 0.9 1.5 1 1 0 1 1 1 1 Vitamin-D-receptor interacting Mediator subunit 4 Cyclin_C PF02984.19 PSC74209.1 - 0.027 14.5 1.8 2.8 8.1 0.2 2.4 2 0 0 2 2 2 0 Cyclin, C-terminal domain Peptidase_C12 PF01088.21 PSC74209.1 - 0.069 12.9 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase, family 1 FoP_duplication PF13865.6 PSC74209.1 - 3.4 8.3 12.1 8.4 7.0 12.1 1.6 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Proteasome PF00227.26 PSC74210.1 - 4.3e-30 104.6 0.0 5.2e-30 104.4 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Myb_DNA-binding PF00249.31 PSC74212.1 - 1e-06 28.8 0.3 1.9e-06 28.0 0.3 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC74212.1 - 0.0049 17.1 0.0 0.0083 16.4 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain SGL PF08450.12 PSC74213.1 - 6.3e-64 215.9 0.0 7.3e-64 215.7 0.0 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region WW PF00397.26 PSC74213.1 - 0.021 14.9 0.0 0.6 10.2 0.0 2.6 2 0 0 2 2 2 0 WW domain Arylesterase PF01731.20 PSC74213.1 - 0.19 11.9 0.0 0.86 9.9 0.0 2.1 3 0 0 3 3 3 0 Arylesterase Lipase_GDSL_2 PF13472.6 PSC74214.1 - 0.053 13.9 0.5 0.26 11.7 0.1 2.5 2 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase family Lactamase_B_2 PF12706.7 PSC74215.1 - 6.6e-35 120.5 0.0 1.3e-34 119.5 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 PSC74215.1 - 2.2e-10 40.7 0.0 3.1e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 PSC74215.1 - 0.00077 19.5 0.1 0.0051 16.8 0.0 2.2 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily UCH PF00443.29 PSC74216.1 - 1.1e-40 139.8 0.0 1.8e-40 139.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PSC74216.1 - 1.2e-19 71.1 0.0 3e-19 69.8 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 PSC74217.1 - 1.1e-40 139.8 0.0 1.8e-40 139.1 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PSC74217.1 - 1.2e-19 71.1 0.0 3e-19 69.8 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Chitin_synth_1 PF01644.17 PSC74218.1 - 1.6e-41 142.0 0.0 3.7e-41 140.8 0.0 1.6 2 0 0 2 2 2 1 Chitin synthase Chitin_synth_2 PF03142.15 PSC74218.1 - 8.6e-21 74.1 7.1 3.8e-18 65.4 0.2 2.9 2 1 1 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.11 PSC74218.1 - 2.7e-11 43.2 0.0 5.4e-11 42.3 0.0 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 PSC74218.1 - 2.8e-10 40.5 5.4 9.4e-10 38.7 5.4 1.9 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 PSC74218.1 - 4.5e-06 26.7 0.0 1.2e-05 25.4 0.0 1.7 1 1 1 2 2 2 1 Glycosyltransferase like family 2 DUF2231 PF09990.9 PSC74218.1 - 5.8 7.4 12.7 3.8 8.0 1.7 3.6 3 0 0 3 3 3 0 Predicted membrane protein (DUF2231) DUF872 PF05915.12 PSC74219.1 - 4.7e-12 46.1 0.9 7e-12 45.5 0.9 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF872) Mito_carr PF00153.27 PSC74220.1 - 1.5e-65 217.1 14.4 1.8e-22 79.0 0.0 3.4 4 0 0 4 4 4 3 Mitochondrial carrier protein Phage_GPD PF05954.11 PSC74220.1 - 0.06 12.6 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) Serine_protease PF18405.1 PSC74220.1 - 0.19 10.8 5.2 0.92 8.6 0.3 3.2 2 1 1 4 4 4 0 Gammaproteobacterial serine protease SMK-1 PF04802.15 PSC74221.1 - 6.3e-64 215.3 0.2 1.3e-63 214.4 0.2 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Fez1 PF06818.15 PSC74221.1 - 0.046 14.2 0.2 0.046 14.2 0.2 5.3 1 1 3 4 4 4 0 Fez1 EF-hand_9 PF14658.6 PSC74221.1 - 0.15 12.5 0.3 0.5 10.7 0.0 2.0 2 0 0 2 2 2 0 EF-hand domain SAM_KSR1 PF13543.6 PSC74221.1 - 0.55 10.4 3.8 2.4 8.3 0.1 3.5 3 0 0 3 3 3 0 SAM like domain present in kinase suppressor RAS 1 CENP-F_leu_zip PF10473.9 PSC74221.1 - 2.2 8.3 21.3 14 5.6 1.1 5.9 5 1 1 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 PSC74221.1 - 5 7.2 8.3 12 6.0 0.3 3.9 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus SMK-1 PF04802.15 PSC74222.1 - 6.3e-64 215.3 0.2 1.3e-63 214.4 0.2 1.5 1 0 0 1 1 1 1 Component of IIS longevity pathway SMK-1 Fez1 PF06818.15 PSC74222.1 - 0.04 14.4 0.2 0.04 14.4 0.2 5.3 1 1 4 5 5 5 0 Fez1 EF-hand_9 PF14658.6 PSC74222.1 - 0.13 12.6 0.0 0.5 10.7 0.0 2.0 1 0 0 1 1 1 0 EF-hand domain SAM_KSR1 PF13543.6 PSC74222.1 - 0.55 10.4 3.8 2.4 8.3 0.1 3.5 3 0 0 3 3 3 0 SAM like domain present in kinase suppressor RAS 1 CENP-F_leu_zip PF10473.9 PSC74222.1 - 2.2 8.3 21.3 14 5.6 1.1 5.9 5 1 1 6 6 6 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 UPF0242 PF06785.11 PSC74222.1 - 5 7.2 8.3 12 6.0 0.3 3.9 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus Peptidase_C1 PF00112.23 PSC74223.1 - 8.3e-46 156.8 1.0 1.7e-45 155.8 1.0 1.5 1 0 0 1 1 1 1 Papain family cysteine protease ShK PF01549.24 PSC74223.1 - 7.7e-31 106.3 100.2 1.6e-07 31.8 10.7 7.6 7 1 0 7 7 7 6 ShK domain-like Neur_chan_memb PF02932.16 PSC74223.1 - 7e-09 36.1 0.0 1.1e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Inhibitor_I29 PF08246.12 PSC74223.1 - 3.3e-06 27.4 2.3 6.2e-06 26.6 2.3 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) zf-CCCH PF00642.24 PSC74223.1 - 0.15 12.0 9.2 17 5.5 0.0 5.3 6 0 0 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) 7TM_GPCR_Srz PF10325.9 PSC74223.1 - 0.17 11.2 5.0 0.28 10.5 5.0 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srz Peptidase_C1 PF00112.23 PSC74224.1 - 8.4e-46 156.8 1.0 1.7e-45 155.8 1.0 1.5 1 0 0 1 1 1 1 Papain family cysteine protease ShK PF01549.24 PSC74224.1 - 1.9e-33 114.7 91.6 1.6e-07 31.7 10.7 7.6 6 1 0 6 6 6 6 ShK domain-like Neur_chan_memb PF02932.16 PSC74224.1 - 3e-08 34.0 0.0 4.9e-08 33.3 0.0 1.4 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Inhibitor_I29 PF08246.12 PSC74224.1 - 3.4e-06 27.4 2.3 6.3e-06 26.5 2.3 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) zf-CCCH PF00642.24 PSC74224.1 - 0.16 11.9 9.2 17 5.4 0.0 5.3 6 0 0 6 6 6 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) YfhO PF09586.10 PSC74224.1 - 0.24 9.6 0.9 0.4 8.9 0.9 1.2 1 0 0 1 1 1 0 Bacterial membrane protein YfhO DNA_pol_phi PF04931.13 PSC74225.1 - 2.9e-110 369.6 0.7 2.4e-57 194.6 0.8 3.2 3 1 0 3 3 3 2 DNA polymerase phi SDA1 PF05285.12 PSC74225.1 - 0.0024 17.4 6.3 0.0024 17.4 6.3 3.2 3 0 0 3 3 3 1 SDA1 Ribosomal_L21p PF00829.21 PSC74226.1 - 1.2e-33 115.3 0.1 1.8e-33 114.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Fasciclin PF02469.22 PSC74226.1 - 2e-12 47.4 0.0 3.1e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain Rgp1 PF08737.10 PSC74227.1 - 0.33 10.1 0.9 0.4 9.8 0.9 1.0 1 0 0 1 1 1 0 Rgp1 FTA4 PF13093.6 PSC74227.1 - 1.7 8.5 8.1 3.3 7.6 8.1 1.5 1 1 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF2161 PF09929.9 PSC74227.1 - 2.7 8.1 5.2 1.1 9.4 2.9 1.6 2 0 0 2 2 2 0 Putative PD-(D/E)XK phosphodiesterase (DUF2161) TFIIA PF03153.13 PSC74227.1 - 3 7.8 8.1 3.4 7.6 8.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ank_5 PF13857.6 PSC74228.1 - 3.5e-05 24.0 0.0 0.0001 22.5 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 PSC74228.1 - 0.00021 21.8 0.0 0.00058 20.4 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC74228.1 - 0.00052 20.5 0.0 0.0012 19.4 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) R3H PF01424.22 PSC74228.1 - 0.0018 18.2 0.0 0.0033 17.4 0.0 1.4 1 0 0 1 1 1 1 R3H domain Ank PF00023.30 PSC74228.1 - 0.026 14.9 0.0 0.18 12.3 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat Ank_3 PF13606.6 PSC74228.1 - 0.062 13.9 0.0 0.65 10.7 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeat RR_TM4-6 PF06459.12 PSC74228.1 - 1.9 8.3 11.0 3.1 7.6 11.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Arf PF00025.21 PSC74229.1 - 8.7e-82 272.8 0.1 1e-81 272.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 PSC74229.1 - 6.4e-14 52.2 0.0 9.1e-14 51.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 PSC74229.1 - 3.9e-13 49.2 0.0 5e-13 48.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 PSC74229.1 - 4.7e-13 49.1 0.0 5.3e-13 48.9 0.0 1.0 1 0 0 1 1 1 1 Ras family G-alpha PF00503.20 PSC74229.1 - 2.6e-12 46.6 1.3 2.4e-08 33.5 0.4 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 PSC74229.1 - 2.2e-10 40.3 0.0 2.7e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PSC74229.1 - 1.9e-05 24.7 0.0 2.8e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 PSC74229.1 - 0.0039 16.5 0.4 0.0098 15.2 0.1 1.7 2 0 0 2 2 2 1 6-phosphofructo-2-kinase UBX PF00789.20 PSC74230.1 - 5.4e-15 55.4 0.0 9.1e-15 54.6 0.0 1.4 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 PSC74230.1 - 5.6e-06 26.1 0.0 1.1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain HIP1_clath_bdg PF16515.5 PSC74230.1 - 0.011 16.3 3.2 0.011 16.3 3.2 1.8 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Macoilin PF09726.9 PSC74230.1 - 5.9 5.3 8.7 8.4 4.8 8.7 1.1 1 0 0 1 1 1 0 Macoilin family SAP18 PF06487.12 PSC74231.1 - 7.4e-37 126.6 0.0 1.1e-36 126.1 0.0 1.3 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Neisseria_TspB PF05616.13 PSC74232.1 - 5.4 5.4 7.6 7.9 4.8 7.6 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein FAM76 PF16046.5 PSC74232.1 - 6.3 6.0 27.7 14 4.9 22.7 2.3 2 0 0 2 2 2 0 FAM76 protein Membralin PF09746.9 PSC74232.1 - 7.1 5.6 11.9 14 4.6 11.9 1.4 1 0 0 1 1 1 0 Tumour-associated protein S1 PF00575.23 PSC74233.1 - 0.00053 20.3 0.0 0.0061 16.9 0.0 2.2 2 0 0 2 2 2 1 S1 RNA binding domain bZIP_1 PF00170.21 PSC74235.1 - 0.00016 21.7 7.5 0.00051 20.1 7.5 1.8 1 0 0 1 1 1 1 bZIP transcription factor GP57 PF17594.2 PSC74235.1 - 0.35 10.6 1.8 0.55 10.0 0.2 2.1 2 0 0 2 2 2 0 Phage Tail fiber assembly helper gene product 57 MMR1 PF08505.10 PSC74235.1 - 4.3 7.6 6.5 12 6.1 2.9 2.6 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Peptidase_A22B PF04258.13 PSC74236.1 - 1.2e-81 274.4 1.7 2.1e-81 273.6 1.7 1.4 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 PSC74236.1 - 7.7e-07 28.9 7.5 1e-06 28.5 5.2 2.2 2 1 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease Presenilin PF01080.17 PSC74236.1 - 0.67 8.7 5.6 0.097 11.4 1.0 1.9 2 0 0 2 2 2 0 Presenilin Peptidase_A22B PF04258.13 PSC74237.1 - 3.6e-82 276.1 1.1 5.4e-82 275.5 1.1 1.2 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 PSC74237.1 - 6.9e-07 29.0 5.2 6.9e-07 29.0 5.2 2.3 2 2 0 2 2 2 1 Signal-peptide peptidase, presenilin aspartyl protease Presenilin PF01080.17 PSC74237.1 - 0.023 13.4 1.3 0.032 13.0 0.0 1.9 2 0 0 2 2 2 0 Presenilin Reticulon PF02453.17 PSC74237.1 - 0.095 12.7 1.4 7.2 6.6 0.7 2.7 3 0 0 3 3 3 0 Reticulon Bestrophin PF01062.21 PSC74238.1 - 6e-42 144.0 0.0 1.2e-41 143.0 0.0 1.4 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Abhydrolase_6 PF12697.7 PSC74238.1 - 2.6e-17 64.1 32.3 2.6e-17 64.1 32.3 4.4 3 2 1 4 4 4 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PSC74238.1 - 1.5e-11 44.4 0.0 6e-11 42.5 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC74238.1 - 1.7e-05 24.2 0.6 0.00027 20.3 0.1 2.5 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 PSC74238.1 - 0.0016 18.6 0.0 0.0042 17.2 0.0 1.6 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 PSC74238.1 - 0.0033 17.1 2.0 0.07 12.8 0.0 2.9 3 0 0 3 3 3 1 Putative esterase SUIM_assoc PF16619.5 PSC74238.1 - 0.007 16.4 3.1 0.02 14.9 3.1 1.8 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 Ser_hydrolase PF06821.13 PSC74238.1 - 0.013 15.4 1.6 0.024 14.5 0.1 2.2 2 0 0 2 2 2 0 Serine hydrolase DUF2722 PF10846.8 PSC74238.1 - 0.021 13.8 0.2 0.028 13.4 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Lipase_3 PF01764.25 PSC74238.1 - 0.023 14.6 0.5 0.049 13.5 0.5 1.5 1 0 0 1 1 1 0 Lipase (class 3) PGAP1 PF07819.13 PSC74238.1 - 0.038 13.7 0.2 0.079 12.7 0.2 1.4 1 0 0 1 1 1 0 PGAP1-like protein Arf PF00025.21 PSC74239.1 - 6.1e-47 159.3 0.0 7.3e-47 159.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 PSC74239.1 - 1.5e-19 70.2 0.0 1.7e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PSC74239.1 - 4.8e-17 62.3 0.0 7.6e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 PSC74239.1 - 2.1e-11 43.6 0.0 2.4e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 PSC74239.1 - 1.6e-08 34.6 0.0 2.3e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PSC74239.1 - 1.9e-08 34.0 0.0 2.1e-08 33.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 PSC74239.1 - 1.6e-06 27.5 0.2 1.7e-05 24.2 0.0 2.1 1 1 1 2 2 2 1 G-protein alpha subunit FeoB_N PF02421.18 PSC74239.1 - 0.02 14.4 0.6 0.038 13.5 0.6 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B ATP_bind_1 PF03029.17 PSC74239.1 - 0.063 13.0 0.0 0.22 11.3 0.0 1.7 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Dynamin_N PF00350.23 PSC74239.1 - 0.077 13.0 0.1 0.99 9.4 0.1 2.1 1 1 1 2 2 2 0 Dynamin family RsgA_GTPase PF03193.16 PSC74239.1 - 0.081 12.8 0.0 8.4 6.3 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase Xpo1 PF08389.12 PSC74240.1 - 0.062 13.4 0.0 0.15 12.1 0.0 1.7 1 0 0 1 1 1 0 Exportin 1-like protein Mito_carr PF00153.27 PSC74242.1 - 8.2e-60 198.8 0.6 6.7e-20 70.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 PSC74243.1 - 8.2e-60 198.8 0.6 6.7e-20 70.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Mito_carr PF00153.27 PSC74244.1 - 8.2e-60 198.8 0.6 6.7e-20 70.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein NUC173 PF08161.12 PSC74246.1 - 1.7e-50 171.5 0.0 1.7e-47 161.8 0.0 3.1 3 0 0 3 3 3 2 NUC173 domain HEAT PF02985.22 PSC74246.1 - 0.017 15.3 7.2 0.82 10.1 0.2 5.7 5 0 0 5 5 5 0 HEAT repeat Gcn1_N PF12074.8 PSC74246.1 - 0.02 14.2 0.3 0.057 12.7 0.3 1.7 1 0 0 1 1 1 0 Generalcontrol nonderepressible 1 (Gcn1) N-terminal DUF3730 PF12530.8 PSC74246.1 - 0.043 13.4 1.4 0.15 11.6 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3730) SBP PF03110.14 PSC74248.1 - 9.1e-31 106.0 5.7 1.6e-30 105.2 5.7 1.4 1 0 0 1 1 1 1 SBP domain PRIMA1 PF16101.5 PSC74248.1 - 0.34 10.9 5.4 1.1 9.4 5.4 1.9 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 PSC74248.1 - 0.45 10.5 3.5 0.77 9.8 3.5 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Mpv17_PMP22 PF04117.12 PSC74249.1 - 1.7e-24 85.8 2.8 2.8e-24 85.1 2.8 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family Methyltransf_23 PF13489.6 PSC74250.1 - 5e-07 29.7 0.0 1.9e-06 27.8 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 PSC74250.1 - 1.7e-06 27.9 0.0 0.063 13.0 0.0 2.7 2 1 0 2 2 2 2 Lysine methyltransferase Methyltransf_12 PF08242.12 PSC74250.1 - 2.7e-05 24.8 1.6 6.1e-05 23.7 0.0 2.4 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC74250.1 - 0.011 15.6 0.1 0.58 9.9 0.0 2.5 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_25 PF13649.6 PSC74250.1 - 0.68 10.7 5.1 0.91 10.3 0.0 3.1 3 1 0 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.12 PSC74250.1 - 2 9.1 6.3 0.42 11.3 0.2 3.0 3 1 0 3 3 3 0 Methyltransferase domain FUSC_2 PF13515.6 PSC74251.1 - 5.4e-10 39.5 8.6 5.4e-10 39.5 8.6 4.5 4 2 0 4 4 4 1 Fusaric acid resistance protein-like DUF645 PF04875.12 PSC74251.1 - 0.038 14.0 1.6 0.92 9.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function, DUF645 ArAE_1 PF06081.11 PSC74251.1 - 0.2 11.8 0.1 0.2 11.8 0.1 2.7 3 0 0 3 3 3 0 Aromatic acid exporter family member 1 ALMT PF11744.8 PSC74251.1 - 1.6 7.5 2.9 3.2 6.5 2.9 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter LPMO_10 PF03067.15 PSC74252.1 - 8.3e-24 85.3 2.8 1.1e-23 85.0 2.8 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading DEAD PF00270.29 PSC74253.1 - 1.1e-16 61.1 0.0 2.2e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC74253.1 - 3.2e-13 50.0 0.0 8.3e-13 48.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RQC PF09382.10 PSC74253.1 - 8.9e-13 48.0 0.0 1.8e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 PSC74253.1 - 3.7e-11 42.8 0.0 8.5e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 HRDC domain HTH_40 PF14493.6 PSC74253.1 - 3.7e-07 30.5 0.0 9.2e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain RecQ_Zn_bind PF16124.5 PSC74253.1 - 7.5e-06 26.6 0.0 1.9e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 RecQ zinc-binding ResIII PF04851.15 PSC74253.1 - 0.0056 16.7 0.0 0.011 15.7 0.0 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Peptidase_S8 PF00082.22 PSC74254.1 - 1.5e-36 126.2 10.3 1.5e-36 126.2 10.3 1.9 1 1 1 2 2 2 1 Subtilase family PAN_4 PF14295.6 PSC74254.1 - 0.016 15.1 1.3 2.1 8.3 0.7 2.6 2 0 0 2 2 2 0 PAN domain SBP PF03110.14 PSC74255.1 - 1.3e-37 128.0 23.7 9.2e-21 73.9 6.3 3.9 3 0 0 3 3 3 2 SBP domain Branch PF02485.21 PSC74255.1 - 3.8e-22 79.0 0.0 8.3e-22 77.9 0.0 1.6 1 0 0 1 1 1 1 Core-2/I-Branching enzyme Exonuc_VII_L PF02601.15 PSC74255.1 - 0.0017 18.0 20.7 0.0017 18.0 20.7 3.3 3 0 0 3 3 3 1 Exonuclease VII, large subunit Nudix_N_2 PF14803.6 PSC74255.1 - 2.8 8.0 5.5 6.1 6.9 1.1 2.8 2 0 0 2 2 2 0 Nudix N-terminal DUF572 PF04502.13 PSC74255.1 - 3.7 7.1 58.6 1.1 8.8 47.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) BSD PF03909.17 PSC74256.1 - 1.2e-05 25.2 0.3 5.1e-05 23.2 0.2 2.0 2 0 0 2 2 2 1 BSD domain Lipase_3 PF01764.25 PSC74257.1 - 1.9e-09 37.5 0.0 5.7e-06 26.2 0.0 2.4 2 0 0 2 2 2 2 Lipase (class 3) MMR_HSR1 PF01926.23 PSC74258.1 - 1.7e-06 28.1 0.0 6.2e-06 26.3 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PSC74258.1 - 0.00062 19.7 0.0 0.0022 17.9 0.0 1.8 1 1 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 PSC74258.1 - 0.019 15.4 0.6 0.67 10.3 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain DUF844 PF05815.11 PSC74258.1 - 0.038 13.2 0.3 0.057 12.6 0.3 1.2 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF844) Ras PF00071.22 PSC74258.1 - 0.22 11.1 0.0 5.2 6.6 0.0 2.2 2 0 0 2 2 2 0 Ras family Roc PF08477.13 PSC74258.1 - 0.26 11.5 0.0 27 5.0 0.0 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase WD40 PF00400.32 PSC74259.1 - 2.4e-45 151.6 7.0 6.3e-07 30.0 0.0 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC74259.1 - 3e-10 40.3 0.0 0.044 14.1 0.0 5.2 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PSC74259.1 - 8.6e-06 25.3 0.0 0.00063 19.2 0.0 2.6 2 1 0 3 3 3 1 WD40-like domain Kelch_6 PF13964.6 PSC74259.1 - 0.01 16.1 0.8 0.65 10.4 0.0 3.8 4 1 1 5 5 5 0 Kelch motif VID27 PF08553.10 PSC74259.1 - 0.012 14.6 0.0 0.033 13.2 0.0 1.6 2 0 0 2 2 2 0 VID27 C-terminal WD40-like domain Ge1_WD40 PF16529.5 PSC74259.1 - 0.054 12.5 0.4 33 3.3 0.0 4.0 3 2 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PSC74259.1 - 0.062 11.9 0.1 0.83 8.2 0.0 2.6 1 1 1 2 2 2 0 Nucleoporin Nup120/160 PQQ PF01011.21 PSC74259.1 - 0.13 12.2 0.7 2.2 8.4 0.0 3.1 4 0 0 4 4 4 0 PQQ enzyme repeat tRNA-synt_2 PF00152.20 PSC74260.1 - 3e-78 263.1 0.0 3.8e-78 262.7 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 PSC74260.1 - 1.2e-11 44.5 0.0 2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 PSC74260.1 - 0.00038 20.0 0.2 0.33 10.4 0.0 2.6 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) Isochorismatase PF00857.20 PSC74262.1 - 1e-27 97.4 0.0 1.2e-27 97.2 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family NTF2 PF02136.20 PSC74263.1 - 0.0036 17.8 0.0 0.0056 17.2 0.0 1.5 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF4440 PF14534.6 PSC74263.1 - 0.018 15.4 0.0 0.018 15.4 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4440) WD40 PF00400.32 PSC74264.1 - 4.3e-13 49.5 7.6 0.007 17.2 0.6 6.0 6 1 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC74264.1 - 0.0058 16.9 0.0 11 6.4 0.0 3.6 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PSC74264.1 - 0.26 9.9 0.0 2.1 6.9 0.0 1.9 2 0 0 2 2 2 0 Nucleoporin Nup120/160 Hint PF01079.20 PSC74266.1 - 3.2e-16 59.5 0.0 4.5e-10 39.4 0.0 2.3 2 0 0 2 2 2 2 Hint module MACPF PF01823.19 PSC74266.1 - 2.4e-11 44.1 0.3 3.6e-11 43.6 0.3 1.2 1 0 0 1 1 1 1 MAC/Perforin domain Laminin_EGF PF00053.24 PSC74266.1 - 9.8 6.4 9.8 0.86 9.8 4.4 2.0 2 0 0 2 2 2 0 Laminin EGF domain Chalcone_2 PF16035.5 PSC74267.1 - 1.7e-12 47.6 0.0 8.4e-06 25.7 0.0 2.1 2 0 0 2 2 2 2 Chalcone isomerase like Chalcone_3 PF16036.5 PSC74267.1 - 1.2e-08 35.3 0.0 1.7e-07 31.5 0.0 2.1 1 1 0 1 1 1 1 Chalcone isomerase-like Chalcone PF02431.15 PSC74267.1 - 3.8e-07 29.7 0.0 5.1e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Chalcone-flavanone isomerase MFS_1 PF07690.16 PSC74268.1 - 1.4e-22 80.1 23.2 2.3e-22 79.4 23.2 1.2 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 PSC74268.1 - 0.15 10.9 9.4 0.026 13.4 0.9 2.7 2 1 0 3 3 3 0 Sugar (and other) transporter Zip PF02535.22 PSC74270.1 - 5.3e-49 167.2 9.4 7.9e-49 166.7 9.4 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4381 PF14316.6 PSC74270.1 - 0.076 13.2 0.2 0.076 13.2 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4381) DLIC PF05783.11 PSC74270.1 - 0.34 9.7 0.2 0.74 8.6 0.2 1.5 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) BSD PF03909.17 PSC74272.1 - 1.2e-11 44.4 0.3 2.1e-11 43.7 0.3 1.4 1 0 0 1 1 1 1 BSD domain SRP-alpha_N PF04086.13 PSC74272.1 - 1.8 8.4 10.8 0.17 11.7 6.1 1.7 2 0 0 2 2 2 0 Signal recognition particle, alpha subunit, N-terminal SOG2 PF10428.9 PSC74272.1 - 5.1 6.2 12.8 7.2 5.7 12.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Utp14 PF04615.13 PSC74272.1 - 7.5 5.0 16.2 0.14 10.7 6.6 2.0 2 0 0 2 2 2 0 Utp14 protein Ferric_reduct PF01794.19 PSC74273.1 - 9.6e-10 38.7 10.7 9.6e-10 38.7 10.7 2.6 3 0 0 3 3 3 1 Ferric reductase like transmembrane component NAD_binding_6 PF08030.12 PSC74273.1 - 0.00012 22.3 0.0 0.00037 20.6 0.0 1.7 1 1 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 PSC74273.1 - 0.17 12.0 0.0 0.48 10.5 0.0 1.7 2 0 0 2 2 2 0 FAD-binding domain Vps54 PF07928.12 PSC74274.1 - 5.9e-43 146.5 0.0 1.2e-42 145.5 0.0 1.6 1 0 0 1 1 1 1 Vps54-like protein Vps54_N PF10475.9 PSC74274.1 - 3.3e-07 29.9 0.0 8.9e-07 28.5 0.0 1.7 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG5 PF10392.9 PSC74274.1 - 0.0019 18.4 0.2 0.0045 17.2 0.2 1.6 1 0 0 1 1 1 1 Golgi transport complex subunit 5 Zw10 PF06248.13 PSC74274.1 - 0.013 14.1 0.0 0.022 13.3 0.0 1.2 1 0 0 1 1 1 0 Centromere/kinetochore Zw10 SPX PF03105.19 PSC74275.1 - 2.9e-20 73.5 7.7 2.7e-09 37.4 3.4 3.8 3 1 0 3 3 3 2 SPX domain UQ_con PF00179.26 PSC74276.1 - 6.5e-44 149.0 0.0 7.6e-44 148.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 PSC74276.1 - 0.0046 16.8 0.0 0.0082 16.0 0.0 1.4 1 1 0 1 1 1 1 UEV domain RWD PF05773.22 PSC74276.1 - 0.018 15.3 0.0 0.021 15.1 0.0 1.2 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 PSC74276.1 - 0.027 14.2 0.0 0.034 13.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B MFS_MOT1 PF16983.5 PSC74277.1 - 0.38 11.2 9.2 0.58 10.6 1.2 2.4 2 0 0 2 2 2 0 Molybdate transporter of MFS superfamily DUF4328 PF14219.6 PSC74277.1 - 0.8 9.2 11.0 0.29 10.7 2.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) DUF2165 PF09933.9 PSC74277.1 - 4.3 7.4 8.2 2.3 8.3 2.2 2.1 2 0 0 2 2 2 0 Predicted small integral membrane protein (DUF2165) DciA PF05258.12 PSC74278.1 - 0.091 13.2 0.3 0.4 11.1 0.1 2.1 2 0 0 2 2 2 0 Dna[CI] antecedent, DciA Fasciclin PF02469.22 PSC74279.1 - 3.8e-32 111.2 0.0 3e-15 56.6 0.0 5.6 6 1 0 6 6 6 3 Fasciclin domain FMO-like PF00743.19 PSC74279.1 - 1.6e-25 89.5 0.0 2.3e-14 52.7 0.0 3.2 3 0 0 3 3 3 3 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 PSC74279.1 - 1.5e-09 37.6 0.0 7.6e-09 35.2 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 PSC74279.1 - 9.4e-05 21.8 0.0 0.00022 20.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Sec5 PF15469.6 PSC74280.1 - 1.1e-26 93.9 0.0 1.5e-26 93.3 0.0 1.2 1 0 0 1 1 1 1 Exocyst complex component Sec5 Vps51 PF08700.11 PSC74280.1 - 7.7e-05 22.7 0.0 0.0002 21.4 0.0 1.7 1 0 0 1 1 1 1 Vps51/Vps67 ApoO PF09769.9 PSC74280.1 - 0.034 14.1 0.1 0.58 10.1 0.0 2.5 2 0 0 2 2 2 0 Apolipoprotein O FtsJ PF01728.19 PSC74281.1 - 9.3e-41 139.9 0.0 1.1e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 PSC74281.1 - 3.6e-05 24.4 0.1 0.00016 22.3 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC74281.1 - 0.00012 21.9 0.0 0.00068 19.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.6 PSC74281.1 - 0.0018 19.3 0.0 0.0036 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC74281.1 - 0.0025 18.4 0.6 0.045 14.4 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC74281.1 - 0.0062 16.4 0.0 0.013 15.4 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC74281.1 - 0.024 15.4 0.2 0.13 13.0 0.0 2.4 3 1 0 3 3 3 0 Methyltransferase domain TFIIA PF03153.13 PSC74282.1 - 0.64 10.0 11.5 0.87 9.5 11.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 PSC74282.1 - 1.4 8.5 8.4 2.4 7.7 8.4 1.3 1 0 0 1 1 1 0 Spt20 family Pkinase PF00069.25 PSC74284.1 - 3e-73 246.4 0.0 3.8e-73 246.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74284.1 - 2.5e-33 115.4 0.0 3.6e-33 114.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC74284.1 - 5.5e-06 25.9 0.1 0.00026 20.4 0.0 2.1 1 1 0 2 2 2 2 Kinase-like Haspin_kinase PF12330.8 PSC74284.1 - 0.01 14.8 0.0 0.03 13.3 0.0 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Aa_trans PF01490.18 PSC74285.1 - 1.1e-47 162.7 20.5 1.5e-47 162.3 20.5 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 PSC74285.1 - 7.2e-05 22.0 10.5 7.2e-05 22.0 10.5 2.4 1 1 3 4 4 4 1 Tryptophan/tyrosine permease family SET PF00856.28 PSC74286.1 - 2.5e-10 41.0 0.0 5.4e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 SET domain DUF1356 PF07092.12 PSC74286.1 - 2.1e-08 33.8 0.0 3e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1356) Rubis-subs-bind PF09273.11 PSC74286.1 - 0.00031 21.4 0.1 0.00069 20.3 0.1 1.6 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding zf-RING_2 PF13639.6 PSC74287.1 - 3e-12 46.7 10.7 3e-12 46.7 10.7 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PSC74287.1 - 2.2e-08 33.8 10.8 2.2e-08 33.8 10.8 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zinc_ribbon_9 PF14369.6 PSC74287.1 - 2.9e-08 33.8 2.6 2.9e-08 33.8 2.6 2.7 2 0 0 2 2 2 1 zinc-ribbon zf-RING_11 PF17123.5 PSC74287.1 - 2.1e-07 30.6 6.0 4.9e-07 29.4 6.0 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 PSC74287.1 - 6.8e-07 29.0 12.3 6e-05 22.8 6.1 2.3 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) SET PF00856.28 PSC74287.1 - 1.3e-06 28.9 0.0 8.4e-06 26.3 0.0 2.1 2 0 0 2 2 2 1 SET domain zf-rbx1 PF12678.7 PSC74287.1 - 2.5e-06 27.7 7.3 2.5e-06 27.7 7.3 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_1 PF14446.6 PSC74287.1 - 2.2e-05 24.3 16.0 0.00051 19.9 4.6 3.4 3 0 0 3 3 3 2 Prokaryotic RING finger family 1 zf-RING_5 PF14634.6 PSC74287.1 - 4.3e-05 23.4 18.5 0.00046 20.1 9.0 2.4 2 0 0 2 2 2 2 zinc-RING finger domain zf-C3HC4 PF00097.25 PSC74287.1 - 0.00047 20.0 9.4 0.00047 20.0 9.4 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rubis-subs-bind PF09273.11 PSC74287.1 - 0.0025 18.5 0.1 0.0053 17.4 0.1 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding zf-ANAPC11 PF12861.7 PSC74287.1 - 0.012 15.7 2.7 0.028 14.5 2.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.14 PSC74287.1 - 0.1 12.5 8.3 0.2 11.5 0.2 3.4 3 1 1 4 4 4 0 Rad50 zinc hook motif zinc_ribbon_16 PF17034.5 PSC74287.1 - 0.16 12.2 1.2 0.42 10.8 1.2 1.6 1 0 0 1 1 1 0 Zinc-ribbon like family zinc_ribbon_12 PF11331.8 PSC74287.1 - 0.21 11.4 0.9 0.83 9.5 0.9 2.1 1 0 0 1 1 1 0 Probable zinc-ribbon domain zf-TFIIB PF13453.6 PSC74287.1 - 0.32 10.4 3.3 6.9 6.1 0.1 3.3 3 0 0 3 3 3 0 Transcription factor zinc-finger DZR PF12773.7 PSC74287.1 - 0.36 10.9 13.5 0.044 13.8 1.1 3.0 3 0 0 3 3 3 0 Double zinc ribbon RINGv PF12906.7 PSC74287.1 - 0.37 11.0 9.2 0.7 10.1 9.2 1.5 1 0 0 1 1 1 0 RING-variant domain UPF0547 PF10571.9 PSC74287.1 - 0.55 10.4 8.4 2.4 8.3 1.7 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 Prok-RING_4 PF14447.6 PSC74287.1 - 1.9 8.4 16.5 0.22 11.4 9.0 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 PSC74287.1 - 2.9 8.0 19.8 0.02 14.9 10.8 2.1 2 0 0 2 2 1 0 RING-type zinc-finger HypA PF01155.19 PSC74287.1 - 7.5 6.6 9.6 0.33 11.0 0.4 2.4 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA RNA_pol_L_2 PF13656.6 PSC74288.1 - 1.7e-23 82.2 0.0 2e-23 81.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 PSC74288.1 - 2.5e-06 26.8 0.0 4.3e-06 26.1 0.0 1.4 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain CDP-OH_P_transf PF01066.21 PSC74290.1 - 1.5e-10 41.7 0.5 3.6e-10 40.5 0.5 1.7 1 0 0 1 1 1 1 CDP-alcohol phosphatidyltransferase TPD PF14811.6 PSC74291.1 - 5.5e-48 162.3 0.0 9.3e-48 161.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function TPD sequence-motif AOX PF01786.17 PSC74291.1 - 8.9e-33 113.7 0.3 1.7e-32 112.8 0.3 1.4 1 0 0 1 1 1 1 Alternative oxidase ADH_zinc_N PF00107.26 PSC74291.1 - 1.6e-22 79.8 0.5 3.5e-22 78.8 0.5 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PSC74291.1 - 1.5e-15 58.4 0.0 6.8e-15 56.3 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PSC74291.1 - 4.6e-07 29.7 0.1 2.8e-06 27.2 0.0 2.2 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 PSC74291.1 - 0.05 13.5 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase DUF1636 PF07845.11 PSC74292.1 - 0.017 15.5 0.2 0.075 13.5 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1636) IHO1 PF15771.5 PSC74292.1 - 0.1 11.4 3.4 0.15 10.8 3.4 1.1 1 0 0 1 1 1 0 Interactor of HORMAD1 protein 1 AF-4 PF05110.13 PSC74292.1 - 1.2 7.1 9.4 1.5 6.8 9.4 1.2 1 0 0 1 1 1 0 AF-4 proto-oncoprotein IMUP PF15761.5 PSC74292.1 - 2.2 9.0 12.8 0.21 12.3 7.4 2.1 2 0 0 2 2 2 0 Immortalisation up-regulated protein DUF755 PF05501.11 PSC74292.1 - 5.4 7.3 10.0 9.2 6.6 10.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Pyr_redox_2 PF07992.14 PSC74293.1 - 6.1e-34 117.6 3.4 1e-33 116.9 3.4 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PSC74293.1 - 2.5e-11 44.0 1.4 5.6e-07 30.0 0.5 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PSC74293.1 - 6.3e-06 26.3 2.1 0.32 11.0 0.0 4.1 4 0 0 4 4 4 2 FAD-NAD(P)-binding DAO PF01266.24 PSC74293.1 - 1e-05 25.3 6.9 0.0062 16.2 0.0 3.2 2 1 1 3 3 3 2 FAD dependent oxidoreductase GIDA PF01134.22 PSC74293.1 - 1.7e-05 24.1 6.8 0.29 10.2 0.0 4.1 4 0 0 4 4 4 3 Glucose inhibited division protein A NAD_binding_7 PF13241.6 PSC74293.1 - 2.6e-05 24.6 0.9 0.26 11.7 0.7 2.5 2 1 0 2 2 2 2 Putative NAD(P)-binding K_oxygenase PF13434.6 PSC74293.1 - 5.5e-05 22.5 1.7 0.0017 17.6 0.0 2.8 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) AlaDh_PNT_C PF01262.21 PSC74293.1 - 0.00025 20.4 4.1 0.087 12.1 0.0 2.7 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_8 PF13450.6 PSC74293.1 - 0.00042 20.5 0.0 0.00042 20.5 0.0 4.4 5 0 0 5 5 4 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 PSC74293.1 - 0.00054 19.1 1.8 0.29 10.2 0.8 2.5 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_3 PF13738.6 PSC74293.1 - 0.00056 19.3 0.0 0.026 13.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 PSC74293.1 - 0.00067 18.6 3.7 0.37 9.6 0.0 3.2 3 0 0 3 3 3 2 Tryptophan halogenase Thi4 PF01946.17 PSC74293.1 - 0.017 14.4 3.5 2.3 7.4 0.1 2.4 2 0 0 2 2 2 0 Thi4 family TrkA_N PF02254.18 PSC74293.1 - 0.021 15.1 0.1 3.4 8.0 0.2 2.5 2 0 0 2 2 2 0 TrkA-N domain HI0933_like PF03486.14 PSC74293.1 - 0.022 13.5 4.5 0.14 10.8 0.0 3.0 4 0 0 4 4 4 0 HI0933-like protein FAD_binding_3 PF01494.19 PSC74293.1 - 0.028 13.7 2.2 0.23 10.7 0.0 2.3 2 0 0 2 2 2 0 FAD binding domain DUF1188 PF06690.11 PSC74293.1 - 0.054 13.0 0.0 0.09 12.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1188) FAD_oxidored PF12831.7 PSC74293.1 - 0.35 10.2 0.0 0.35 10.2 0.0 4.2 5 0 0 5 5 3 0 FAD dependent oxidoreductase TPR_1 PF00515.28 PSC74294.1 - 4.7e-12 45.2 3.2 6.1e-07 29.0 0.2 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.17 PSC74294.1 - 3.4e-09 36.1 13.1 3.4e-05 23.6 0.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PSC74294.1 - 4.4e-08 32.7 4.6 3e-07 30.0 1.0 2.5 1 1 1 2 2 2 1 TPR repeat TPR_9 PF13371.6 PSC74294.1 - 2.8e-06 27.4 5.2 2.8e-06 27.4 5.2 3.6 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 PSC74294.1 - 4.5e-05 23.3 0.3 0.042 14.1 0.0 2.8 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 PSC74294.1 - 6.4e-05 23.1 6.0 0.0051 17.1 0.3 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 PSC74294.1 - 0.00057 19.7 1.5 0.07 13.2 0.1 3.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 PSC74294.1 - 0.014 16.2 1.1 0.014 16.2 1.1 5.1 3 2 2 5 5 5 0 Tetratricopeptide repeat RIFIN PF02009.16 PSC74294.1 - 0.015 15.2 1.2 0.015 15.2 1.2 1.5 2 0 0 2 2 2 0 Rifin TPR_10 PF13374.6 PSC74294.1 - 0.1 12.5 10.1 2.6 8.0 0.1 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TFIIA PF03153.13 PSC74294.1 - 0.64 9.9 26.6 0.84 9.6 26.6 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fis1_TPR_C PF14853.6 PSC74294.1 - 0.79 9.8 6.7 6.9 6.8 0.1 2.7 3 0 0 3 3 2 0 Fis1 C-terminal tetratricopeptide repeat DUF1509 PF07420.11 PSC74294.1 - 6.3 5.7 16.1 10 5.0 16.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) WD40 PF00400.32 PSC74295.1 - 2.8e-12 46.9 4.8 0.054 14.4 0.0 6.4 6 0 0 6 6 6 3 WD domain, G-beta repeat Nup160 PF11715.8 PSC74295.1 - 0.064 11.9 0.0 0.18 10.4 0.0 1.6 2 0 0 2 2 2 0 Nucleoporin Nup120/160 CRT10 PF08728.10 PSC74295.1 - 0.084 11.0 0.0 0.14 10.3 0.0 1.3 1 0 0 1 1 1 0 CRT10 MeaB PF03308.16 PSC74296.1 - 9.7e-86 287.1 2.3 1.4e-85 286.5 0.5 1.8 2 0 0 2 2 2 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Nucleotid_trans PF03407.16 PSC74296.1 - 1.2e-11 45.0 0.0 1.9e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase cobW PF02492.19 PSC74296.1 - 2.8e-05 23.8 0.1 0.0001 21.9 0.1 1.8 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain RsgA_GTPase PF03193.16 PSC74296.1 - 0.00092 19.2 0.0 0.52 10.2 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 PSC74296.1 - 0.032 14.0 0.0 0.095 12.5 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein MnmE_helical PF12631.7 PSC74296.1 - 0.065 13.4 0.0 0.089 12.9 0.0 1.3 1 0 0 1 1 1 0 MnmE helical domain AAA_16 PF13191.6 PSC74296.1 - 0.15 12.4 1.1 0.61 10.4 0.1 2.4 2 0 0 2 2 2 0 AAA ATPase domain MMR_HSR1 PF01926.23 PSC74296.1 - 0.17 12.0 0.1 0.31 11.1 0.1 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 PSC74296.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain DnaJ_CXXCXGXG PF00684.19 PSC74297.1 - 3.1e-05 24.3 16.8 0.0036 17.6 17.1 2.7 1 1 0 1 1 1 1 DnaJ central domain DUF1356 PF07092.12 PSC74297.1 - 0.016 14.5 3.3 0.1 11.9 0.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1356) FYVE PF01363.21 PSC74297.1 - 0.021 15.0 4.2 1.3 9.2 0.2 2.2 2 0 0 2 2 2 0 FYVE zinc finger Anti-TRAP PF15777.5 PSC74297.1 - 0.14 12.2 15.8 2.7 8.0 3.9 3.7 2 2 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein DUF5351 PF17302.2 PSC74297.1 - 0.24 11.6 17.4 6.6 7.0 1.7 4.6 4 1 1 5 5 5 0 Family of unknown function (DUF5351) Prim_Zn_Ribbon PF08273.12 PSC74297.1 - 5.8 7.3 13.0 9.3 6.6 1.7 2.3 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF4196 PF13846.6 PSC74298.1 - 0.29 11.3 5.0 23 5.2 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4196) WD40 PF00400.32 PSC74299.1 - 8.2e-38 127.7 11.6 9.3e-11 42.1 0.2 8.0 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC74299.1 - 4.7e-10 39.6 1.1 0.0072 16.6 0.0 5.3 1 1 6 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PSC74299.1 - 3.5e-06 26.2 0.2 0.9 8.4 0.0 4.2 2 2 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein VID27 PF08553.10 PSC74299.1 - 0.00052 19.2 0.0 0.0014 17.7 0.0 1.6 1 1 1 2 2 2 1 VID27 C-terminal WD40-like domain Nucleoporin_N PF08801.11 PSC74299.1 - 0.00077 18.3 0.0 0.15 10.7 0.0 3.4 2 2 1 3 3 3 1 Nup133 N terminal like Nup160 PF11715.8 PSC74299.1 - 0.0011 17.7 6.9 0.24 10.0 0.2 4.3 2 2 1 4 4 4 1 Nucleoporin Nup120/160 PALB2_WD40 PF16756.5 PSC74299.1 - 0.02 13.8 0.5 0.092 11.7 0.3 2.2 1 1 1 2 2 2 0 Partner and localizer of BRCA2 WD40 domain Cytochrom_D1 PF02239.16 PSC74299.1 - 0.023 13.2 0.0 0.48 8.9 0.0 2.5 2 1 0 3 3 3 0 Cytochrome D1 heme domain Frtz PF11768.8 PSC74299.1 - 0.061 11.6 0.0 0.098 11.0 0.0 1.3 1 0 0 1 1 1 0 WD repeat-containing and planar cell polarity effector protein Fritz S-l_SbsC_C PF18316.1 PSC74299.1 - 0.12 12.9 0.2 19 5.8 0.1 3.2 3 0 0 3 3 3 0 S-layer protein SbsC C-terminal domain Hira PF07569.11 PSC74299.1 - 0.22 11.2 0.8 18 5.0 0.1 3.3 2 1 2 4 4 4 0 TUP1-like enhancer of split ABC_tran PF00005.27 PSC74300.1 - 3.8e-24 85.8 0.0 1.1e-23 84.2 0.0 1.8 1 1 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 PSC74300.1 - 1e-09 38.6 0.0 8e-05 22.6 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PSC74300.1 - 2.8e-05 23.7 0.0 0.17 11.3 0.0 2.3 1 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PSC74300.1 - 0.0022 17.7 0.0 0.0045 16.7 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 PSC74300.1 - 0.0075 15.9 1.3 0.028 14.0 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PSC74300.1 - 0.0098 16.2 0.0 0.039 14.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 PSC74300.1 - 0.014 15.6 0.1 0.18 12.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 PSC74300.1 - 0.015 14.9 0.1 0.033 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 PSC74300.1 - 0.069 13.6 0.0 0.54 10.7 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 PSC74300.1 - 0.071 13.0 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_15 PF13175.6 PSC74300.1 - 0.11 12.1 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 PSC74300.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.2 1 0 0 1 1 1 0 RsgA GTPase AAA_23 PF13476.6 PSC74300.1 - 0.18 12.3 0.0 0.27 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PSC74300.1 - 0.19 12.1 9.6 0.013 15.8 2.9 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_5 PF07728.14 PSC74300.1 - 0.2 11.7 0.1 0.48 10.4 0.0 1.6 2 0 0 2 2 1 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 PSC74300.1 - 0.22 10.9 2.3 1.6 8.1 0.1 2.6 3 0 0 3 3 3 0 Magnesium chelatase, subunit ChlI NifU PF01106.17 PSC74301.1 - 7.9e-26 90.0 0.7 8.4e-22 77.1 0.1 3.0 2 1 0 2 2 2 2 NifU-like domain GIY-YIG PF01541.24 PSC74301.1 - 0.091 13.1 0.0 0.19 12.0 0.0 1.5 1 0 0 1 1 1 0 GIY-YIG catalytic domain Peptidase_S9 PF00326.21 PSC74302.1 - 6e-27 94.5 0.1 9.9e-27 93.8 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 PSC74302.1 - 2.8e-06 27.0 0.0 4.8e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_6 PF12697.7 PSC74302.1 - 9.5e-05 23.1 1.2 9.5e-05 23.1 1.2 4.0 2 2 2 4 4 3 1 Alpha/beta hydrolase family Peptidase_S15 PF02129.18 PSC74302.1 - 0.00018 21.2 0.1 0.56 9.8 0.0 2.4 1 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Hydrolase_4 PF12146.8 PSC74302.1 - 0.0005 19.4 0.2 0.58 9.4 0.1 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_3 PF07859.13 PSC74302.1 - 0.001 19.0 0.2 0.0033 17.3 0.1 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold PD40 PF07676.12 PSC74302.1 - 0.033 14.1 0.2 1.4 9.0 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat FSH1 PF03959.13 PSC74302.1 - 0.035 13.8 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Esterase PF00756.20 PSC74302.1 - 0.042 13.5 0.1 0.14 11.8 0.1 1.8 1 1 0 1 1 1 0 Putative esterase Abhydrolase_1 PF00561.20 PSC74302.1 - 0.12 12.0 0.2 7.6 6.1 0.1 2.4 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 PSC74302.1 - 0.16 11.8 0.0 0.53 10.1 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase RCC1 PF00415.18 PSC74303.1 - 3.9e-42 142.6 35.0 7.2e-12 45.7 0.8 8.1 6 2 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat BRX PF08381.11 PSC74303.1 - 3.5e-13 48.7 0.1 6.6e-13 47.8 0.1 1.4 1 0 0 1 1 1 1 Transcription factor regulating root and shoot growth via Pin3 RCC1_2 PF13540.6 PSC74303.1 - 4.2e-11 42.3 38.7 2e-05 24.2 0.0 9.1 11 0 0 11 11 11 3 Regulator of chromosome condensation (RCC1) repeat PH_12 PF16457.5 PSC74303.1 - 0.047 14.2 0.0 0.1 13.1 0.0 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain Mcp5_PH PF12814.7 PSC74303.1 - 0.21 11.7 0.0 0.37 10.9 0.0 1.3 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology HAUS-augmin3 PF14932.6 PSC74303.1 - 0.29 10.7 8.1 4 6.9 3.5 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 PKcGMP_CC PF16808.5 PSC74303.1 - 2 8.3 4.0 3.8 7.5 4.0 1.4 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Spc7 PF08317.11 PSC74303.1 - 4.1 6.2 5.3 25 3.6 1.6 2.3 2 0 0 2 2 2 0 Spc7 kinetochore protein HARE-HTH PF05066.13 PSC74304.1 - 1.9e-15 57.0 0.5 4.3e-15 55.9 0.0 2.0 2 0 0 2 2 2 1 HB1, ASXL, restriction endonuclease HTH domain Homeodomain PF00046.29 PSC74304.1 - 4.3e-10 39.3 0.3 4.3e-10 39.3 0.3 2.0 2 0 0 2 2 2 1 Homeodomain DDT PF02791.17 PSC74304.1 - 4.2e-09 36.6 0.2 4.2e-09 36.6 0.2 2.1 3 0 0 3 3 3 1 DDT domain WSD PF15613.6 PSC74304.1 - 2.3e-07 31.2 0.0 2.3e-07 31.2 0.0 4.2 3 2 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 PSC74304.1 - 1.2e-05 24.7 0.1 3.3e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Homeobox_KN PF05920.11 PSC74304.1 - 0.00026 20.8 0.1 0.00082 19.2 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain HARE-HTH PF05066.13 PSC74305.1 - 1.9e-15 57.0 0.5 4.3e-15 55.8 0.0 2.0 2 0 0 2 2 2 1 HB1, ASXL, restriction endonuclease HTH domain Homeodomain PF00046.29 PSC74305.1 - 4.3e-10 39.3 0.3 4.3e-10 39.3 0.3 2.0 2 0 0 2 2 2 1 Homeodomain DDT PF02791.17 PSC74305.1 - 4.3e-09 36.6 0.2 4.3e-09 36.6 0.2 2.1 3 0 0 3 3 3 1 DDT domain WSD PF15613.6 PSC74305.1 - 2.4e-07 31.2 0.0 2.4e-07 31.2 0.0 4.2 3 2 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 PSC74305.1 - 1.3e-05 24.6 0.1 3.3e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Homeobox_KN PF05920.11 PSC74305.1 - 0.00026 20.8 0.1 0.00082 19.2 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain HARE-HTH PF05066.13 PSC74306.1 - 1.9e-15 57.0 0.5 4.3e-15 55.8 0.0 2.0 2 0 0 2 2 2 1 HB1, ASXL, restriction endonuclease HTH domain Homeodomain PF00046.29 PSC74306.1 - 4.3e-10 39.3 2.2 4.4e-10 39.3 0.3 2.1 2 0 0 2 2 2 1 Homeodomain DDT PF02791.17 PSC74306.1 - 4.3e-09 36.6 0.2 4.3e-09 36.6 0.2 2.2 3 0 0 3 3 3 1 DDT domain WSD PF15613.6 PSC74306.1 - 2.4e-07 31.2 0.0 2.4e-07 31.2 0.0 4.5 3 2 0 3 3 3 1 Williams-Beuren syndrome DDT (WSD), D-TOX E motif WHIM1 PF15612.6 PSC74306.1 - 1.2e-05 24.8 0.1 3.3e-05 23.3 0.1 1.9 1 0 0 1 1 1 1 WSTF, HB1, Itc1p, MBD9 motif 1 Homeobox_KN PF05920.11 PSC74306.1 - 0.00027 20.8 0.1 0.00083 19.2 0.1 1.9 1 0 0 1 1 1 1 Homeobox KN domain Agenet PF05641.12 PSC74307.1 - 0.013 16.0 0.0 0.023 15.2 0.0 1.4 1 0 0 1 1 1 0 Agenet domain UPF0560 PF10577.9 PSC74307.1 - 4.2 5.8 7.5 6.4 5.1 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 Spt20 PF12090.8 PSC74307.1 - 5.2 6.6 13.8 1.2 8.6 5.5 2.2 2 0 0 2 2 2 0 Spt20 family DAGK_acc PF00609.19 PSC74308.1 - 1.7e-50 171.5 0.0 2.9e-50 170.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.24 PSC74308.1 - 4.5e-19 68.3 0.0 9.8e-19 67.2 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.22 PSC74308.1 - 1.8e-10 40.5 3.5 0.00025 20.8 0.5 2.5 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_9 PF13901.6 PSC74308.1 - 0.16 11.9 8.7 1.4 8.8 2.5 2.5 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon PHD_4 PF16866.5 PSC74308.1 - 0.17 12.0 10.4 0.57 10.3 0.9 2.6 2 0 0 2 2 2 0 PHD-finger PHD PF00628.29 PSC74308.1 - 7.7 6.5 14.4 6.1 6.8 3.4 2.9 1 1 0 2 2 2 0 PHD-finger DNA_primase_lrg PF04104.14 PSC74309.1 - 6.8e-55 186.3 0.0 8.6e-55 186.0 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit MAM33 PF02330.16 PSC74310.1 - 1.4e-33 116.7 1.0 5.3e-33 114.7 0.0 2.4 3 0 0 3 3 3 1 Mitochondrial glycoprotein RNase_H PF00075.24 PSC74310.1 - 0.019 15.1 3.7 3.5 7.8 0.3 2.5 2 0 0 2 2 2 0 RNase H DUF5320 PF17253.2 PSC74310.1 - 0.029 15.4 1.2 14 6.8 0.1 2.8 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF16 PF01519.16 PSC74310.1 - 0.069 13.6 1.7 13 6.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF16 DUF4357 PF14267.6 PSC74310.1 - 0.087 12.8 0.4 28 4.8 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4357) Chibby PF14645.6 PSC74310.1 - 0.14 12.6 0.0 36 4.8 0.0 2.6 2 0 0 2 2 2 0 Chibby family Calici_MSP PF05752.11 PSC74310.1 - 0.17 11.7 2.4 14 5.5 0.2 2.8 2 2 0 2 2 2 0 Calicivirus minor structural protein DUF5427 PF10310.9 PSC74310.1 - 0.22 10.4 11.5 1.5 7.7 3.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5427) Mod_r PF07200.13 PSC74310.1 - 0.32 11.1 8.5 3.9 7.6 1.0 2.4 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein ScsC_N PF18312.1 PSC74310.1 - 1.2 9.0 9.5 10 6.1 1.4 3.2 2 0 0 2 2 2 0 Copper resistance protein ScsC N-terminal domain DUF3509 PF12021.8 PSC74310.1 - 5.5 6.8 6.4 95 2.9 0.3 3.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3509) DUF883 PF05957.13 PSC74311.1 - 0.019 15.6 3.4 0.019 15.6 3.4 3.2 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) BNR PF02012.20 PSC74311.1 - 9.9 6.6 10.8 1.8 8.9 0.6 3.9 3 0 0 3 3 3 0 BNR/Asp-box repeat NAD_binding_10 PF13460.6 PSC74312.1 - 2.2e-42 145.0 0.8 2.6e-42 144.8 0.8 1.0 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 PSC74312.1 - 9.3e-18 64.6 0.4 3e-17 63.0 0.4 1.8 1 1 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 PSC74312.1 - 1.9e-07 30.8 0.1 3e-07 30.2 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PSC74312.1 - 6.5e-07 28.6 0.2 8.6e-07 28.2 0.2 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.18 PSC74312.1 - 0.0012 19.1 0.3 0.0012 19.1 0.3 1.7 2 0 0 2 2 2 1 TrkA-N domain adh_short PF00106.25 PSC74312.1 - 0.0023 17.4 1.0 0.0023 17.4 1.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase TPR_12 PF13424.6 PSC74313.1 - 0.00078 19.7 4.8 0.00078 19.7 4.8 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat NCBP3 PF10309.9 PSC74313.1 - 0.00083 19.2 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Nuclear cap-binding protein subunit 3 TPR_2 PF07719.17 PSC74313.1 - 0.032 14.3 1.0 0.094 12.9 1.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_14 PF13428.6 PSC74313.1 - 0.048 14.5 3.1 0.048 14.5 3.1 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 PSC74313.1 - 0.058 13.3 0.4 0.058 13.3 0.4 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat SOUL PF04832.12 PSC74314.1 - 2e-30 106.2 0.9 2.4e-30 105.9 0.9 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein LRR_8 PF13855.6 PSC74315.1 - 3.4e-24 84.4 4.6 9.1e-16 57.4 1.4 3.4 1 1 2 3 3 3 3 Leucine rich repeat Helicase_C PF00271.31 PSC74315.1 - 8.5e-21 74.4 0.0 2.5e-20 72.9 0.0 1.8 2 0 0 2 2 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC74315.1 - 4.5e-18 65.8 0.0 1.8e-17 63.9 0.0 2.1 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PSC74315.1 - 7.3e-18 64.9 0.0 2.1e-17 63.5 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase LRR_4 PF12799.7 PSC74315.1 - 1.3e-15 57.3 0.9 7.8e-05 23.0 0.2 3.4 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 PSC74315.1 - 3e-08 33.4 0.0 0.0057 16.2 0.0 3.2 1 1 2 3 3 3 3 Leucine-rich repeat PHD PF00628.29 PSC74315.1 - 4.9e-07 29.5 7.3 1.1e-06 28.4 7.3 1.6 1 0 0 1 1 1 1 PHD-finger LRR_1 PF00560.33 PSC74315.1 - 0.0074 16.7 5.1 46 5.1 0.1 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat zf-HC5HC2H_2 PF13832.6 PSC74315.1 - 0.12 12.6 0.8 0.38 10.9 0.8 1.9 1 0 0 1 1 1 0 PHD-zinc-finger like domain C1_2 PF03107.16 PSC74315.1 - 1.3 9.4 4.0 3.1 8.2 4.0 1.6 1 0 0 1 1 1 0 C1 domain PHD_2 PF13831.6 PSC74315.1 - 1.9 8.1 4.2 3.8 7.1 4.2 1.5 1 0 0 1 1 1 0 PHD-finger KH_6 PF15985.5 PSC74316.1 - 1.3e-12 47.8 0.0 2.9e-12 46.7 0.0 1.6 2 0 0 2 2 2 1 KH domain Rrp40_N PF18311.1 PSC74316.1 - 0.00078 19.3 0.2 0.0014 18.5 0.2 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain MU2_FHA PF18221.1 PSC74316.1 - 0.059 13.4 0.0 0.16 12.0 0.0 1.8 1 1 0 1 1 1 0 Mutator 2 Fork head associated domain WD40 PF00400.32 PSC74317.1 - 2.1e-11 44.2 0.2 0.0003 21.5 0.2 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC74317.1 - 2.5e-08 34.1 0.0 0.08 13.3 0.0 4.6 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DUF2415 PF10313.9 PSC74317.1 - 0.052 13.5 0.0 0.11 12.4 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein domain (DUF2415) FHA PF00498.26 PSC74318.1 - 2.4e-16 59.8 0.0 4e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 FHA domain zf-CCHC PF00098.23 PSC74318.1 - 3.3e-15 55.4 15.2 3.2e-09 36.5 3.2 2.4 2 0 0 2 2 2 2 Zinc knuckle Yop-YscD_cpl PF16697.5 PSC74318.1 - 0.0018 18.6 0.0 0.036 14.4 0.0 2.2 1 1 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-CCHC_5 PF14787.6 PSC74318.1 - 0.0078 15.9 10.1 0.13 12.0 1.7 2.5 2 0 0 2 2 2 2 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 PSC74318.1 - 0.079 12.9 0.2 0.079 12.9 0.2 3.0 2 1 1 3 3 3 0 Zinc knuckle zf-CCHC_4 PF14392.6 PSC74318.1 - 0.36 10.6 4.7 2.1 8.1 0.3 2.3 2 0 0 2 2 2 0 Zinc knuckle potato_inhibit PF00280.18 PSC74319.1 - 1.1e-16 61.2 0.0 1.5e-16 60.8 0.0 1.2 1 0 0 1 1 1 1 Potato inhibitor I family Inhibitor_I78 PF11720.8 PSC74319.1 - 0.0061 16.6 0.0 0.0087 16.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase inhibitor I78 family DUF4048 PF13257.6 PSC74319.1 - 0.042 13.7 0.1 0.048 13.5 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4048) PASTA PF03793.19 PSC74319.1 - 0.075 12.9 0.0 0.13 12.2 0.0 1.4 1 0 0 1 1 1 0 PASTA domain SNF2_N PF00176.23 PSC74320.1 - 4.9e-52 176.8 0.0 9.6e-52 175.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC74320.1 - 5.4e-19 68.6 0.0 1e-18 67.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 PSC74320.1 - 4.1e-06 26.2 0.0 8.5e-06 25.2 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 PSC74320.1 - 2.9e-05 24.1 0.0 0.0001 22.4 0.0 1.9 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 PSC74320.1 - 0.04 13.6 0.0 0.16 11.6 0.0 1.9 2 0 0 2 2 2 0 SWI2/SNF2 ATPase Nop14 PF04147.12 PSC74321.1 - 0.0016 16.7 2.5 0.0016 16.7 2.5 1.8 2 0 0 2 2 2 1 Nop14-like family Se-cys_synth_N PF12390.8 PSC74321.1 - 1.8 8.8 0.0 1.8 8.8 0.0 5.3 4 1 0 4 4 4 0 Selenocysteine synthase N terminal CDC45 PF02724.14 PSC74321.1 - 1.8 6.7 7.1 0.06 11.6 0.8 1.6 2 0 0 2 2 2 0 CDC45-like protein DUF4746 PF15928.5 PSC74321.1 - 2.6 7.4 4.6 5.5 6.3 4.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF1749 PF08538.10 PSC74322.1 - 7e-41 140.3 0.0 1.1e-40 139.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) SNF2_N PF00176.23 PSC74322.1 - 1.2e-20 73.6 0.0 2.2e-20 72.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-GRF PF06839.12 PSC74322.1 - 1.5e-12 47.4 6.8 2.8e-12 46.5 6.8 1.5 1 0 0 1 1 1 1 GRF zinc finger Helicase_C PF00271.31 PSC74322.1 - 8.3e-09 35.8 0.0 2.2e-08 34.4 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Hydrolase_4 PF12146.8 PSC74322.1 - 0.00069 18.9 0.1 0.0031 16.8 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EutB PF06751.11 PSC74322.1 - 0.18 10.6 0.0 0.3 9.9 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) DUF1749 PF08538.10 PSC74323.1 - 6.8e-41 140.3 0.0 1.1e-40 139.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) SNF2_N PF00176.23 PSC74323.1 - 1.2e-20 73.6 0.0 2.1e-20 72.8 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-GRF PF06839.12 PSC74323.1 - 1.5e-12 47.4 6.8 2.8e-12 46.5 6.8 1.5 1 0 0 1 1 1 1 GRF zinc finger Helicase_C PF00271.31 PSC74323.1 - 4.5e-09 36.6 0.0 9.3e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Hydrolase_4 PF12146.8 PSC74323.1 - 0.00069 19.0 0.1 0.0031 16.8 0.1 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 EutB PF06751.11 PSC74323.1 - 0.18 10.6 0.0 0.29 9.9 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine ammonia lyase large subunit (EutB) MT PF12777.7 PSC74324.1 - 0.082 11.9 0.3 0.25 10.3 0.8 1.4 2 0 0 2 2 2 0 Microtubule-binding stalk of dynein motor MT PF12777.7 PSC74325.1 - 0.082 11.9 0.3 0.25 10.3 0.8 1.4 2 0 0 2 2 2 0 Microtubule-binding stalk of dynein motor Calpain_inhib PF00748.19 PSC74326.1 - 1.3 9.5 5.4 1.7 9.2 0.0 2.4 2 0 0 2 2 2 0 Calpain inhibitor DUF4407 PF14362.6 PSC74326.1 - 1.9 7.8 10.8 3.1 7.1 5.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) T2SSM PF04612.12 PSC74326.1 - 8.2 6.5 25.8 2.5 8.2 0.1 4.3 4 0 0 4 4 4 0 Type II secretion system (T2SS), protein M Trehalose_PPase PF02358.16 PSC74327.1 - 1e-57 195.0 0.0 1.4e-57 194.5 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase HAD PF12710.7 PSC74327.1 - 0.14 12.5 0.0 0.98 9.8 0.0 2.3 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase TFIIA PF03153.13 PSC74327.1 - 0.16 11.9 16.4 0.38 10.7 6.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TraV PF09676.10 PSC74327.1 - 1.4 9.9 6.0 0.86 10.6 0.7 2.5 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) SARAF PF06682.12 PSC74327.1 - 2.8 7.5 10.3 0.64 9.6 0.4 2.1 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis ANAPC_CDC26 PF10471.9 PSC74327.1 - 4.1 8.3 20.2 9.4 7.2 5.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Amidinotransf PF02274.17 PSC74328.1 - 2.9e-51 174.6 0.0 4.5e-51 173.9 0.0 1.3 1 0 0 1 1 1 1 Amidinotransferase Uso1_p115_head PF04869.14 PSC74328.1 - 4.2e-11 42.5 0.0 1.3e-10 40.9 0.0 1.9 1 1 0 1 1 1 1 Uso1 / p115 like vesicle tethering protein, head region Uso1_p115_C PF04871.13 PSC74328.1 - 1.7e-09 38.1 6.1 1.7e-09 38.1 6.1 2.7 1 1 1 2 2 2 1 Uso1 / p115 like vesicle tethering protein, C terminal region HALZ PF02183.18 PSC74328.1 - 0.024 14.9 6.3 0.18 12.0 0.4 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Arm_vescicular PF18770.1 PSC74328.1 - 0.029 14.3 0.0 0.093 12.7 0.0 1.9 1 0 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor DUF4407 PF14362.6 PSC74328.1 - 0.048 13.0 32.7 0.37 10.1 11.8 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 PSC74328.1 - 0.077 13.4 7.7 0.24 11.8 7.7 1.8 1 0 0 1 1 1 0 Fez1 RasGAP_C PF03836.15 PSC74328.1 - 0.097 12.8 0.3 0.62 10.2 0.0 2.2 2 0 0 2 2 2 0 RasGAP C-terminus CENP-F_leu_zip PF10473.9 PSC74328.1 - 0.2 11.7 5.0 0.92 9.5 0.4 2.7 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GIT_CC PF16559.5 PSC74328.1 - 0.24 11.3 4.9 1.9 8.4 1.6 2.6 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor CALCOCO1 PF07888.11 PSC74328.1 - 0.44 9.4 14.0 0.11 11.4 4.6 2.3 2 0 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Spc7 PF08317.11 PSC74328.1 - 1.4 7.8 9.7 3.1 6.6 9.7 1.5 1 0 0 1 1 1 0 Spc7 kinetochore protein TolA_bind_tri PF16331.5 PSC74328.1 - 2.4 8.3 15.1 2.9 8.0 1.2 3.1 3 0 0 3 3 3 0 TolA binding protein trimerisation TraB PF01963.17 PSC74329.1 - 1.3e-20 74.4 0.2 4.6e-20 72.6 0.2 1.7 1 1 0 1 1 1 1 TraB family HrpB1_HrpK PF09613.10 PSC74329.1 - 0.11 12.2 0.0 0.28 10.8 0.0 1.7 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB1_HrpK) Thioredoxin PF00085.20 PSC74330.1 - 4.3e-30 103.8 0.0 5e-30 103.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 PSC74330.1 - 6.7e-05 23.1 0.0 0.00012 22.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 PSC74330.1 - 0.00012 22.5 0.0 0.0002 21.8 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 PSC74330.1 - 0.0016 17.8 0.0 0.0017 17.7 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 PSC74330.1 - 0.0068 16.3 0.0 0.0088 16.0 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PSC74330.1 - 0.016 14.9 0.0 0.019 14.7 0.0 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.6 PSC74330.1 - 0.028 14.6 0.0 0.041 14.1 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like SNF2_N PF00176.23 PSC74331.1 - 1e-70 238.2 0.9 1.5e-70 237.6 0.9 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC74331.1 - 7.5e-17 61.7 0.0 1.6e-16 60.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HSA PF07529.13 PSC74331.1 - 5.4e-10 39.4 5.1 5.4e-10 39.4 5.1 3.9 3 0 0 3 3 3 1 HSA ResIII PF04851.15 PSC74331.1 - 3.1e-08 33.8 0.0 7e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PSC74331.1 - 4e-06 26.7 0.0 1.1e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DBINO PF13892.6 PSC74331.1 - 0.0051 17.2 10.5 0.0051 17.2 10.5 4.0 3 1 0 3 3 3 1 DNA-binding domain FAM199X PF15814.5 PSC74332.1 - 0.016 14.3 1.4 0.027 13.6 1.4 1.3 1 0 0 1 1 1 0 Protein family FAM199X DNA_primase_lrg PF04104.14 PSC74333.1 - 9e-75 251.5 0.0 1.1e-74 251.2 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DUF4149 PF13664.6 PSC74334.1 - 4.9e-28 97.4 4.2 4.9e-28 97.4 4.2 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4149) DUF1772 PF08592.11 PSC74334.1 - 0.53 10.6 15.4 16 5.8 15.4 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1772) UPF0242 PF06785.11 PSC74335.1 - 0.0045 17.1 0.6 0.0086 16.2 0.6 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus TMF_DNA_bd PF12329.8 PSC74335.1 - 0.011 15.7 0.7 0.028 14.4 0.4 1.8 1 1 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Fez1 PF06818.15 PSC74335.1 - 0.025 15.0 1.0 0.041 14.3 1.0 1.3 1 0 0 1 1 1 0 Fez1 Spc7 PF08317.11 PSC74335.1 - 0.18 10.6 3.4 0.33 9.8 2.4 1.8 2 0 0 2 2 2 0 Spc7 kinetochore protein DUF2570 PF10828.8 PSC74335.1 - 0.78 9.6 3.5 1.6 8.6 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) ATG16 PF08614.11 PSC74335.1 - 0.89 9.7 11.9 0.055 13.7 6.5 1.7 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) NPV_P10 PF05531.12 PSC74337.1 - 0.00073 19.9 3.2 0.0011 19.4 3.2 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus P10 protein LPP PF04728.13 PSC74337.1 - 0.0063 16.9 0.9 0.0091 16.4 0.9 1.3 1 0 0 1 1 1 1 Lipoprotein leucine-zipper DUF1664 PF07889.12 PSC74337.1 - 0.011 15.8 2.4 0.015 15.3 2.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HlyE PF06109.13 PSC74337.1 - 0.022 14.1 0.3 0.029 13.7 0.3 1.1 1 0 0 1 1 1 0 Haemolysin E (HlyE) GrpE PF01025.19 PSC74337.1 - 0.033 13.9 0.1 0.04 13.6 0.1 1.1 1 0 0 1 1 1 0 GrpE Laminin_II PF06009.12 PSC74337.1 - 0.035 14.1 1.2 0.051 13.6 1.2 1.2 1 0 0 1 1 1 0 Laminin Domain II SKA1 PF07160.12 PSC74337.1 - 0.041 13.7 0.4 0.052 13.4 0.4 1.1 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 EzrA PF06160.12 PSC74337.1 - 0.043 12.0 1.2 0.054 11.7 1.2 1.0 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA XhlA PF10779.9 PSC74337.1 - 0.093 12.9 7.6 0.18 12.0 7.6 1.6 1 1 0 1 1 1 0 Haemolysin XhlA Type2_restr_D3 PF16902.5 PSC74337.1 - 0.14 12.1 5.5 0.37 10.7 2.6 2.6 1 1 1 2 2 2 0 Type-2 restriction enzyme D3 domain COG2 PF06148.11 PSC74337.1 - 0.15 12.2 0.3 0.19 11.8 0.3 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 KxDL PF10241.9 PSC74337.1 - 0.18 12.1 0.5 0.25 11.7 0.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein DASH_Duo1 PF08651.10 PSC74337.1 - 0.21 11.4 2.2 0.41 10.5 1.3 1.7 1 1 1 2 2 2 0 DASH complex subunit Duo1 Pkinase PF00069.25 PSC74338.1 - 2.1e-43 148.6 0.2 1.1e-42 146.2 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain EamA PF00892.20 PSC74338.1 - 5e-19 68.8 22.6 4.1e-10 40.0 3.9 2.6 2 0 0 2 2 2 2 EamA-like transporter family Pkinase_Tyr PF07714.17 PSC74338.1 - 1.3e-16 60.7 1.3 1.5e-16 60.4 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.23 PSC74338.1 - 0.02 14.8 0.0 0.02 14.8 0.0 6.2 3 1 1 4 4 4 0 Phosphotransferase enzyme family Choline_kinase PF01633.20 PSC74338.1 - 0.44 10.1 0.0 0.44 10.1 0.0 1.9 2 0 0 2 2 2 0 Choline/ethanolamine kinase DUF3395 PF11875.8 PSC74339.1 - 1.8e-26 92.9 4.2 1.8e-26 92.9 4.2 4.5 5 1 0 5 5 5 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 PSC74339.1 - 1.4e-22 79.5 0.7 2.7e-22 78.7 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain PilM PF07419.12 PSC74339.1 - 0.32 11.2 0.0 0.32 11.2 0.0 3.2 4 0 0 4 4 4 0 PilM DUF3395 PF11875.8 PSC74340.1 - 1.6e-26 93.0 4.0 1.6e-26 93.0 4.0 4.5 5 1 0 5 5 5 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 PSC74340.1 - 1.4e-22 79.5 0.7 2.7e-22 78.7 0.7 1.5 1 0 0 1 1 1 1 DnaJ domain PilM PF07419.12 PSC74340.1 - 0.32 11.2 0.0 0.32 11.2 0.0 3.2 4 0 0 4 4 4 0 PilM CCT PF06203.14 PSC74341.1 - 1.1e-13 51.0 11.4 1.8e-13 50.3 11.4 1.3 1 0 0 1 1 1 1 CCT motif RabGAP-TBC PF00566.18 PSC74343.1 - 1.1e-48 165.7 0.0 1.5e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Peptidase_C1 PF00112.23 PSC74345.1 - 3.6e-52 177.6 0.0 5.7e-52 177.0 0.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 PSC74345.1 - 3.4e-13 49.8 1.1 5.1e-13 49.3 1.1 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 PSC74345.1 - 0.00018 20.4 0.2 0.0093 14.8 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Tfb4 PF03850.14 PSC74346.1 - 1.5e-71 241.1 0.0 3.2e-71 240.1 0.0 1.5 1 1 0 1 1 1 1 Transcription factor Tfb4 Sulfotransfer_3 PF13469.6 PSC74347.1 - 1.1e-33 117.4 0.0 2.3e-33 116.4 0.0 1.5 1 1 0 1 1 1 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PSC74347.1 - 1.7e-06 27.7 0.0 5.7e-06 26.0 0.0 1.8 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_4 PF17784.1 PSC74347.1 - 0.022 14.6 0.0 0.42 10.4 0.0 2.2 2 0 0 2 2 2 0 Sulfotransferase domain FA_hydroxylase PF04116.13 PSC74348.1 - 1.1e-18 67.8 22.0 1.1e-18 67.8 22.0 1.9 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily CH_2 PF06294.11 PSC74349.1 - 2.6e-31 107.6 0.7 4.5e-31 106.8 0.0 1.7 2 0 0 2 2 2 1 CH-like domain in sperm protein CAMSAP_CH PF11971.8 PSC74349.1 - 4.5e-14 52.1 0.0 7.2e-14 51.4 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain CH PF00307.31 PSC74349.1 - 0.00033 20.8 0.2 0.00096 19.3 0.0 1.7 2 0 0 2 2 2 1 Calponin homology (CH) domain DUF641 PF04859.12 PSC74349.1 - 0.0067 16.8 5.3 0.01 16.1 3.7 1.9 2 0 0 2 2 2 1 Plant protein of unknown function (DUF641) mit_SMPDase PF14724.6 PSC74349.1 - 0.053 11.5 0.1 0.074 11.0 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial-associated sphingomyelin phosphodiesterase TPR_1 PF00515.28 PSC74350.1 - 4.3e-50 165.6 21.4 6.1e-09 35.3 0.1 9.8 10 0 0 10 10 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 PSC74350.1 - 4.6e-47 154.4 28.9 3.1e-06 26.9 0.1 10.7 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.6 PSC74350.1 - 1.6e-45 152.5 29.8 1.2e-07 31.2 0.0 9.7 3 2 6 9 9 9 8 TPR repeat Glyco_transf_41 PF13844.6 PSC74350.1 - 4e-41 141.0 0.0 7.3e-20 70.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_8 PF13181.6 PSC74350.1 - 6.5e-38 125.8 4.7 4.2e-06 26.5 0.0 9.3 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_17 PF13431.6 PSC74350.1 - 1.1e-32 110.1 18.7 2.2e-05 24.5 0.1 10.1 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 PSC74350.1 - 2.7e-30 104.7 72.5 9.4e-09 35.8 0.2 8.3 5 1 1 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 PSC74350.1 - 1e-28 97.2 24.2 1.5e-06 27.8 0.0 10.0 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_12 PF13424.6 PSC74350.1 - 2.5e-28 98.2 44.0 1.4e-07 31.7 1.2 7.2 4 3 3 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.6 PSC74350.1 - 1.8e-23 81.2 48.0 0.0023 18.6 0.8 11.5 3 3 7 10 10 10 7 Tetratricopeptide repeat TPR_19 PF14559.6 PSC74350.1 - 1.6e-20 73.4 42.3 2.5e-06 27.9 0.0 7.4 3 3 4 8 8 8 7 Tetratricopeptide repeat TPR_9 PF13371.6 PSC74350.1 - 2.3e-19 69.3 42.4 7.9e-07 29.1 0.7 7.0 4 1 3 7 7 7 6 Tetratricopeptide repeat TPR_6 PF13174.6 PSC74350.1 - 9.7e-15 54.1 18.9 0.072 13.8 0.0 9.6 10 0 0 10 10 9 4 Tetratricopeptide repeat TPR_10 PF13374.6 PSC74350.1 - 1.3e-14 53.5 48.5 2.2e-05 24.2 1.2 9.6 8 1 1 9 9 9 5 Tetratricopeptide repeat NARP1 PF12569.8 PSC74350.1 - 3.8e-06 26.1 0.2 0.25 10.2 0.0 3.4 3 0 0 3 3 3 2 NMDA receptor-regulated protein 1 EST1_DNA_bind PF10373.9 PSC74350.1 - 0.0001 21.9 12.2 0.00061 19.3 0.3 3.2 3 1 0 3 3 3 2 Est1 DNA/RNA binding domain ANAPC3 PF12895.7 PSC74350.1 - 0.00025 21.2 18.4 0.023 14.9 2.2 5.0 4 1 1 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 PSC74350.1 - 0.00051 19.4 15.4 0.035 13.3 1.3 5.4 2 2 1 5 5 5 2 Tetratricopeptide repeat Coatomer_E PF04733.14 PSC74350.1 - 0.0011 18.4 1.6 0.043 13.2 0.1 3.2 3 1 2 5 5 4 1 Coatomer epsilon subunit Fis1_TPR_C PF14853.6 PSC74350.1 - 0.0037 17.3 4.5 0.44 10.7 0.1 4.4 4 1 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 PSC74350.1 - 0.0053 17.2 35.2 0.025 15.0 3.6 5.5 2 1 2 5 5 5 2 Bacterial transcriptional activator domain TPR_4 PF07721.14 PSC74350.1 - 0.0099 16.4 50.2 0.14 12.8 0.3 10.3 9 0 0 9 9 7 2 Tetratricopeptide repeat FAT PF02259.23 PSC74350.1 - 0.018 14.3 0.1 4.1 6.5 0.0 2.6 1 1 0 2 2 2 0 FAT domain Wzy_C_2 PF11846.8 PSC74350.1 - 0.025 14.5 12.4 0.056 13.4 1.0 4.2 2 1 2 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal HrpB1_HrpK PF09613.10 PSC74350.1 - 0.072 12.7 3.3 5.1 6.8 0.2 3.0 2 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB1_HrpK) TPR_20 PF14561.6 PSC74350.1 - 0.21 11.9 27.9 0.51 10.7 0.5 7.2 6 1 0 7 7 7 0 Tetratricopeptide repeat RPN7 PF10602.9 PSC74350.1 - 0.44 10.2 2.5 7.2 6.3 0.1 3.8 2 2 2 5 5 5 0 26S proteasome subunit RPN7 ChAPs PF09295.10 PSC74350.1 - 0.8 8.6 2.0 31 3.4 0.0 3.4 5 0 0 5 5 5 0 ChAPs (Chs5p-Arf1p-binding proteins) C2 PF00168.30 PSC74351.1 - 2.8e-32 111.1 0.0 9.7e-16 57.9 0.1 2.5 2 0 0 2 2 2 2 C2 domain SMP_LBD PF17047.5 PSC74351.1 - 4.6e-16 58.8 0.0 6.8e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 Synaptotagmin-like mitochondrial-lipid-binding domain OCRE PF17780.1 PSC74352.1 - 9.4e-13 48.0 0.4 9.4e-13 48.0 0.4 1.7 2 0 0 2 2 2 1 OCRE domain SAP PF02037.27 PSC74352.1 - 0.00055 19.6 0.0 0.001 18.7 0.0 1.5 1 0 0 1 1 1 1 SAP domain Ish1 PF10281.9 PSC74352.1 - 0.028 14.7 0.0 0.074 13.4 0.0 1.7 1 0 0 1 1 1 0 Putative stress-responsive nuclear envelope protein Pes-10 PF07149.11 PSC74352.1 - 9.2 5.2 10.0 18 4.2 10.0 1.4 1 0 0 1 1 1 0 Pes-10 FKBP_C PF00254.28 PSC74353.1 - 4.6e-08 33.3 0.0 1.6e-07 31.6 0.0 1.9 1 1 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase adh_short_C2 PF13561.6 PSC74354.1 - 4.1e-51 173.8 6.6 1.5e-50 171.9 6.6 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PSC74354.1 - 6.1e-42 143.3 4.4 1.5e-41 142.0 4.4 1.6 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PSC74354.1 - 1.6e-05 24.9 0.6 1.6e-05 24.9 0.6 1.6 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 PSC74354.1 - 0.0063 16.0 0.2 0.035 13.6 0.2 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Adeno_E4_ORF3 PF06931.11 PSC74354.1 - 0.13 12.5 0.1 18 5.6 0.0 2.3 1 1 1 2 2 2 0 Mastadenovirus E4 ORF3 protein Methyltransf_11 PF08241.12 PSC74355.1 - 2.5e-35 121.0 1.0 1.3e-18 67.4 0.0 3.8 4 0 0 4 4 4 2 Methyltransferase domain Methyltransf_25 PF13649.6 PSC74355.1 - 3e-33 114.4 0.9 2.9e-18 66.4 0.0 3.3 4 0 0 4 4 4 2 Methyltransferase domain Methyltransf_31 PF13847.6 PSC74355.1 - 8.5e-28 97.1 0.0 6.1e-20 71.6 0.0 2.5 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_12 PF08242.12 PSC74355.1 - 1.5e-22 80.2 0.2 4.2e-14 53.1 0.0 3.1 3 0 0 3 3 3 2 Methyltransferase domain Methyltransf_23 PF13489.6 PSC74355.1 - 6.6e-22 78.1 0.0 3.5e-17 62.7 0.0 2.2 2 0 0 2 2 2 2 Methyltransferase domain Ubie_methyltran PF01209.18 PSC74355.1 - 4.5e-14 52.4 0.0 8.3e-09 35.1 0.0 3.0 2 1 1 3 3 3 2 ubiE/COQ5 methyltransferase family CMAS PF02353.20 PSC74355.1 - 1.1e-12 47.9 0.0 2.4e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.11 PSC74355.1 - 3.3e-06 26.9 0.0 0.024 14.3 0.0 2.4 2 0 0 2 2 2 2 Nodulation protein S (NodS) UPF0020 PF01170.18 PSC74355.1 - 3.7e-05 23.5 0.0 0.0011 18.6 0.0 2.3 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 PCMT PF01135.19 PSC74355.1 - 8.5e-05 22.4 0.0 0.0039 17.0 0.0 2.6 3 0 0 3 3 3 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CheR PF01739.18 PSC74355.1 - 0.00017 21.1 0.0 0.026 14.0 0.0 3.2 3 1 1 4 4 4 1 CheR methyltransferase, SAM binding domain TehB PF03848.14 PSC74355.1 - 0.00033 20.1 0.0 0.32 10.4 0.0 2.3 2 0 0 2 2 2 2 Tellurite resistance protein TehB Methyltransf_32 PF13679.6 PSC74355.1 - 0.00053 20.0 0.0 0.26 11.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain RrnaAD PF00398.20 PSC74355.1 - 0.0012 18.0 0.0 0.015 14.4 0.0 2.1 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase MetW PF07021.12 PSC74355.1 - 0.0024 17.5 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_15 PF09445.10 PSC74355.1 - 0.0078 15.8 0.1 0.045 13.3 0.0 2.2 2 1 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_PK PF05891.12 PSC74355.1 - 0.024 14.2 0.0 0.063 12.8 0.0 1.7 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Bin3 PF06859.12 PSC74355.1 - 0.048 14.3 0.0 1.8 9.3 0.0 2.8 3 0 0 3 3 3 0 Bicoid-interacting protein 3 (Bin3) Methyltransf_28 PF02636.17 PSC74355.1 - 0.088 12.4 0.2 0.79 9.3 0.0 2.3 2 1 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase PrmA PF06325.13 PSC74355.1 - 0.097 12.1 0.0 1 8.7 0.0 2.2 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) zf-CCCH_6 PF18585.1 PSC74355.1 - 0.37 10.7 1.0 0.66 9.9 0.1 1.8 2 0 0 2 2 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 ABC1 PF03109.16 PSC74356.1 - 9.9e-29 99.9 0.0 1.9e-28 99.0 0.0 1.5 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 PSC74356.1 - 2.3e-06 27.7 2.3 2.5e-06 27.6 0.1 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase PF00069.25 PSC74356.1 - 0.036 13.4 0.0 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74357.1 - 2.2e-24 86.2 0.0 5.7e-22 78.2 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PSC74357.1 - 6.9e-23 81.3 0.0 5.2e-21 75.2 0.0 2.1 1 1 1 2 2 2 1 Protein kinase domain DUF1997 PF09366.10 PSC74357.1 - 8.1e-10 39.0 0.0 8.3e-05 22.8 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1997) GAF_2 PF13185.6 PSC74357.1 - 3.4e-06 27.4 0.4 3.4e-06 27.4 0.4 2.5 2 0 0 2 2 2 1 GAF domain GAF PF01590.26 PSC74357.1 - 9.9e-06 26.2 1.0 2.2e-05 25.1 0.3 2.0 2 0 0 2 2 2 1 GAF domain GAF_3 PF13492.6 PSC74357.1 - 8.4e-05 22.9 0.3 8.4e-05 22.9 0.3 2.1 2 0 0 2 2 2 1 GAF domain Pkinase_fungal PF17667.1 PSC74357.1 - 0.0014 17.5 0.0 0.0021 16.9 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 PSC74357.1 - 0.0059 16.0 0.1 0.046 13.1 0.0 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PSC74357.1 - 0.059 12.7 0.0 0.096 12.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Period_C PF12114.8 PSC74357.1 - 1.4 8.4 3.0 2.6 7.6 3.0 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region RWP-RK PF02042.15 PSC74358.1 - 2.3e-16 59.5 0.0 5.4e-16 58.3 0.0 1.6 1 0 0 1 1 1 1 RWP-RK domain Tetraspanin PF00335.20 PSC74358.1 - 3.2e-05 23.7 4.3 0.00012 21.9 4.3 1.8 1 1 0 1 1 1 1 Tetraspanin family MttA_Hcf106 PF02416.16 PSC74359.1 - 0.00036 19.8 1.1 0.00036 19.8 1.1 1.9 2 0 0 2 2 2 1 mttA/Hcf106 family Spt20 PF12090.8 PSC74359.1 - 9.1 5.8 13.8 12 5.5 13.8 1.2 1 0 0 1 1 1 0 Spt20 family WD40 PF00400.32 PSC74360.1 - 2.2e-07 31.4 6.6 0.025 15.5 0.1 4.7 6 0 0 6 6 6 2 WD domain, G-beta repeat WD40 PF00400.32 PSC74361.1 - 1.1e-06 29.3 8.3 0.028 15.3 0.1 4.8 6 0 0 6 6 6 2 WD domain, G-beta repeat TPR_16 PF13432.6 PSC74362.1 - 2e-36 124.4 88.0 1.6e-08 35.1 1.5 8.9 6 1 4 10 10 10 8 Tetratricopeptide repeat TPR_2 PF07719.17 PSC74362.1 - 2.5e-34 114.6 45.8 0.0026 17.7 0.1 14.1 15 0 0 15 15 14 10 Tetratricopeptide repeat TPR_14 PF13428.6 PSC74362.1 - 1.9e-32 109.1 89.9 1.7e-05 25.3 0.3 15.0 2 2 12 15 15 15 9 Tetratricopeptide repeat TPR_19 PF14559.6 PSC74362.1 - 4.1e-27 94.5 43.0 3e-07 30.8 0.0 9.7 5 3 6 11 11 11 8 Tetratricopeptide repeat TPR_8 PF13181.6 PSC74362.1 - 3.8e-24 82.8 3.4 0.013 15.7 0.0 11.8 13 0 0 13 13 12 3 Tetratricopeptide repeat TPR_12 PF13424.6 PSC74362.1 - 2.3e-21 75.8 54.6 0.00034 20.8 2.2 10.3 5 5 5 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.6 PSC74362.1 - 2.6e-21 75.0 7.6 0.0013 18.3 0.0 9.3 5 3 5 10 10 10 4 TPR repeat TPR_17 PF13431.6 PSC74362.1 - 2e-20 71.6 14.1 0.0056 17.0 0.3 10.2 11 1 0 11 11 11 4 Tetratricopeptide repeat TPR_1 PF00515.28 PSC74362.1 - 2.7e-20 71.3 10.6 0.36 10.7 0.3 10.7 11 0 0 11 11 10 5 Tetratricopeptide repeat TPR_15 PF13429.6 PSC74362.1 - 1e-12 47.8 35.4 4e-06 26.3 5.9 6.4 1 1 5 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 PSC74362.1 - 5.1e-09 36.1 50.5 7.1e-06 26.1 0.8 7.8 4 3 4 9 9 9 5 Tetratricopeptide repeat TPR_7 PF13176.6 PSC74362.1 - 4.8e-07 29.4 32.0 0.069 13.2 0.1 11.5 13 1 0 13 13 11 2 Tetratricopeptide repeat TPR_10 PF13374.6 PSC74362.1 - 1.3e-06 28.1 60.1 0.082 12.8 0.1 11.9 14 0 0 14 14 13 4 Tetratricopeptide repeat ANAPC3 PF12895.7 PSC74362.1 - 2.8e-06 27.5 10.7 0.021 15.1 0.3 4.5 4 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 Mad3_BUB1_I PF08311.12 PSC74362.1 - 8.5e-05 22.5 5.8 16 5.5 0.0 7.0 8 0 0 8 8 7 0 Mad3/BUB1 homology region 1 Suf PF05843.14 PSC74362.1 - 0.0011 19.0 0.0 4.5 7.2 0.0 3.6 4 1 0 4 4 4 2 Suppressor of forked protein (Suf) HrpB1_HrpK PF09613.10 PSC74362.1 - 0.0011 18.6 9.3 0.058 13.0 0.0 4.5 3 2 1 4 4 4 2 Bacterial type III secretion protein (HrpB1_HrpK) TPR_6 PF13174.6 PSC74362.1 - 0.0018 18.8 35.2 0.34 11.7 0.2 11.7 13 1 1 14 14 13 1 Tetratricopeptide repeat TPR_4 PF07721.14 PSC74362.1 - 0.018 15.6 100.0 0.033 14.8 0.1 13.1 14 0 0 14 14 11 0 Tetratricopeptide repeat DUF4810 PF16068.5 PSC74362.1 - 0.019 15.5 0.8 93 3.7 0.0 5.2 6 2 1 7 7 4 0 Domain of unknown function (DUF4810) DUF3808 PF10300.9 PSC74362.1 - 0.086 11.6 0.1 1.9 7.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3808) TPR_3 PF07720.12 PSC74362.1 - 0.099 12.7 2.1 39 4.4 0.1 4.5 6 0 0 6 6 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 PSC74362.1 - 0.28 11.5 23.9 0.22 11.9 0.2 6.8 4 3 2 7 7 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PSC74362.1 - 0.48 10.5 4.5 56 3.9 0.0 4.7 5 0 0 5 5 5 0 Fis1 C-terminal tetratricopeptide repeat Cytochrom_C_2 PF01322.20 PSC74362.1 - 3 8.8 6.0 0.79 10.6 0.4 2.8 3 0 0 3 3 2 0 Cytochrome C' BTAD PF03704.17 PSC74362.1 - 7.2 7.0 50.6 0.89 10.0 0.3 6.1 3 2 3 6 6 6 0 Bacterial transcriptional activator domain MIT PF04212.18 PSC74362.1 - 8.9 6.5 11.8 24 5.1 0.0 5.7 7 0 0 7 7 6 0 MIT (microtubule interacting and transport) domain TerC PF03741.16 PSC74363.1 - 5.4e-44 150.0 7.3 9.3e-44 149.3 7.3 1.4 1 0 0 1 1 1 1 Integral membrane protein TerC family PARP_reg PF02877.14 PSC74363.1 - 0.069 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase, regulatory domain XPG_I PF00867.18 PSC74364.1 - 8.6e-29 99.7 0.1 1.7e-28 98.8 0.1 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 PSC74364.1 - 5e-25 87.9 0.0 9.8e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 XPG N-terminal domain Polysacc_deac_1 PF01522.21 PSC74364.1 - 4.9e-09 36.1 0.0 1e-08 35.1 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide deacetylase 5_3_exonuc PF01367.20 PSC74364.1 - 5.2e-06 27.0 0.0 1.1e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold LysM PF01476.20 PSC74364.1 - 0.08 13.0 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 LysM domain Telomere_reg-2 PF10193.9 PSC74365.1 - 0.083 13.3 0.8 0.13 12.7 0.8 1.3 1 0 0 1 1 1 0 Telomere length regulation protein Med26 PF08711.11 PSC74366.1 - 7.9e-13 48.2 0.0 1.8e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain Urease_gamma PF00547.18 PSC74366.1 - 0.1 13.0 0.5 0.83 10.0 0.4 2.3 1 1 1 2 2 2 0 Urease, gamma subunit ribosomal_L24 PF17136.4 PSC74367.1 - 1.9e-21 76.2 1.0 4.4e-21 75.0 1.0 1.6 2 0 0 2 2 2 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 PSC74367.1 - 4.6e-05 23.2 1.6 4.6e-05 23.2 1.6 2.4 3 0 0 3 3 3 1 KOW motif Glyco_transf_21 PF13506.6 PSC74368.1 - 4.9e-11 42.4 0.0 8.2e-11 41.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glycos_transf_2 PF00535.26 PSC74368.1 - 1.1e-05 25.3 0.0 2e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PSC74368.1 - 4.1e-05 23.6 0.0 7.3e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Bestrophin PF01062.21 PSC74369.1 - 2e-44 152.1 0.1 2.8e-44 151.7 0.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel S1 PF00575.23 PSC74370.1 - 3.8e-19 68.8 0.4 1.1e-11 44.9 0.5 3.3 3 0 0 3 3 3 2 S1 RNA binding domain AAA PF00004.29 PSC74371.1 - 5.6e-44 149.8 0.0 1.2e-43 148.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 PSC74371.1 - 2.8e-38 131.7 0.0 5.3e-38 130.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 PSC74371.1 - 5.7e-08 32.4 1.3 1.6e-07 31.0 0.0 2.4 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 PSC74371.1 - 4e-05 23.6 0.0 0.00015 21.7 0.0 2.1 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PSC74371.1 - 0.00017 22.0 0.4 0.016 15.6 0.2 2.8 2 1 0 3 3 2 1 AAA ATPase domain IstB_IS21 PF01695.17 PSC74371.1 - 0.0002 21.1 0.2 0.0026 17.5 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.13 PSC74371.1 - 0.0005 19.4 1.3 0.00059 19.2 0.0 1.7 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 PSC74371.1 - 0.00066 19.5 0.0 0.0031 17.3 0.0 2.2 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain Mg_chelatase PF01078.21 PSC74371.1 - 0.0021 17.5 1.5 0.016 14.6 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_22 PF13401.6 PSC74371.1 - 0.0027 18.0 0.0 0.12 12.6 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_28 PF13521.6 PSC74371.1 - 0.0047 17.2 0.3 0.026 14.8 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.6 PSC74371.1 - 0.011 16.2 0.0 0.023 15.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 PSC74371.1 - 0.018 15.2 0.0 0.074 13.2 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_2 PF07724.14 PSC74371.1 - 0.021 15.0 0.0 0.043 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 PSC74371.1 - 0.047 14.2 0.0 0.12 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 PSC74371.1 - 0.05 13.3 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 PSC74371.1 - 0.065 13.4 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF815 PF05673.13 PSC74371.1 - 0.068 12.3 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 PSC74371.1 - 0.1 12.1 0.2 0.37 10.3 0.0 2.0 3 0 0 3 3 3 0 P-loop containing dynein motor region ABC_tran PF00005.27 PSC74371.1 - 0.11 13.0 0.9 0.25 11.9 0.1 2.0 2 0 0 2 2 1 0 ABC transporter PhoH PF02562.16 PSC74371.1 - 0.18 11.2 0.7 0.73 9.2 0.5 2.0 2 0 0 2 2 2 0 PhoH-like protein MFAP1 PF06991.11 PSC74372.1 - 3.3e-48 164.4 19.9 3.3e-48 164.4 19.9 3.2 1 1 1 2 2 2 1 Microfibril-associated/Pre-mRNA processing SAP PF02037.27 PSC74372.1 - 0.074 12.8 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 SAP domain MWFE PF15879.5 PSC74373.1 - 7.5e-11 42.0 0.0 9.1e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit DUF498 PF04430.14 PSC74374.1 - 9.3e-28 96.5 0.0 1.5e-27 95.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) KDZ PF18758.1 PSC74374.1 - 1.1e-12 48.1 2.4 1.4e-12 47.7 2.4 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF2269 PF10027.9 PSC74374.1 - 0.0049 16.9 0.7 0.0049 16.9 0.7 2.1 2 1 1 3 3 3 1 Predicted integral membrane protein (DUF2269) AAA_12 PF13087.6 PSC74375.1 - 5.5e-31 107.8 0.0 1e-30 106.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PSC74375.1 - 1e-18 68.1 0.0 6.6e-09 35.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain AAA_30 PF13604.6 PSC74375.1 - 4e-11 43.0 0.0 1.2e-10 41.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PSC74375.1 - 0.004 17.5 0.0 0.0098 16.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PSC74375.1 - 0.041 14.1 0.0 0.13 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA domain ResIII PF04851.15 PSC74375.1 - 0.094 12.7 0.0 0.25 11.4 0.0 1.6 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.16 PSC74375.1 - 0.16 11.4 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein PfkB PF00294.24 PSC74376.1 - 1.4e-60 205.2 5.9 1.6e-60 205.0 5.9 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 PSC74376.1 - 2.1e-09 37.2 0.2 3.6e-09 36.4 0.2 1.5 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase Carb_kinase PF01256.17 PSC74376.1 - 0.00029 20.4 0.5 0.00042 19.9 0.5 1.2 1 0 0 1 1 1 1 Carbohydrate kinase Ammonium_transp PF00909.21 PSC74377.1 - 1.6e-107 359.7 19.4 2e-107 359.4 19.4 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Ca_hom_mod PF14798.6 PSC74377.1 - 0.19 10.8 2.2 3.8 6.5 0.4 2.2 2 0 0 2 2 2 0 Calcium homeostasis modulator PilN PF05137.13 PSC74378.1 - 0.35 11.0 2.6 0.36 11.0 0.4 2.3 2 1 0 2 2 2 0 Fimbrial assembly protein (PilN) Nnf1 PF03980.14 PSC74379.1 - 2.2e-14 53.8 1.1 3.9e-14 52.9 1.1 1.4 1 0 0 1 1 1 1 Nnf1 ABC_tran_CTD PF16326.5 PSC74379.1 - 0.014 15.6 0.5 0.014 15.6 0.5 2.1 2 1 0 2 2 2 0 ABC transporter C-terminal domain Jnk-SapK_ap_N PF09744.9 PSC74379.1 - 0.016 15.4 0.5 0.033 14.4 0.1 1.6 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Spc7 PF08317.11 PSC74379.1 - 0.073 11.9 0.3 0.12 11.3 0.3 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein Pyr_redox_2 PF07992.14 PSC74380.1 - 1.1e-61 208.6 1.1 1.5e-61 208.2 1.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 PSC74380.1 - 1.1e-39 135.1 0.1 1.9e-39 134.3 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 PSC74380.1 - 1.9e-21 76.4 0.0 7.1e-21 74.6 0.0 2.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PSC74380.1 - 3.5e-09 36.4 0.0 6.4e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 PSC74380.1 - 3.5e-06 26.3 0.7 0.0016 17.6 0.1 2.3 2 0 0 2 2 2 2 Glucose inhibited division protein A K_oxygenase PF13434.6 PSC74380.1 - 3.2e-05 23.3 0.2 0.17 11.0 0.1 2.2 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) UDPG_MGDP_dh_N PF03721.14 PSC74380.1 - 0.0015 18.1 0.1 0.0051 16.4 0.0 1.9 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 PSC74380.1 - 0.006 16.5 0.2 0.019 14.9 0.0 1.9 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 PSC74380.1 - 0.0086 15.4 2.9 1.7 7.8 0.1 2.3 1 1 1 2 2 2 2 FAD binding domain HI0933_like PF03486.14 PSC74380.1 - 0.014 14.1 2.9 0.96 8.1 0.0 3.1 2 1 1 3 3 3 0 HI0933-like protein AlaDh_PNT_C PF01262.21 PSC74380.1 - 0.022 14.1 3.5 0.064 12.5 0.0 3.0 3 1 1 4 4 4 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.24 PSC74380.1 - 0.055 13.1 7.5 1.9 8.0 0.0 3.1 3 0 0 3 3 3 0 FAD dependent oxidoreductase His_Phos_1 PF00300.22 PSC74382.1 - 3.7e-08 33.3 1.2 6.9e-08 32.4 1.2 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Glyco_trans_4_3 PF12000.8 PSC74382.1 - 0.017 14.8 0.4 0.034 13.8 0.3 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 4 group PCI PF01399.27 PSC74383.1 - 8.5e-09 35.9 0.0 1.5e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 PCI domain eIF3m_C_helix PF18005.1 PSC74383.1 - 1.8e-05 24.3 0.5 3.3e-05 23.5 0.5 1.4 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix UPF0016 PF01169.19 PSC74384.1 - 1.6e-39 134.1 19.5 1.2e-21 76.8 6.7 5.8 6 1 0 7 7 5 2 Uncharacterized protein family UPF0016 ABC2_membrane PF01061.24 PSC74384.1 - 2.5e-33 115.3 16.0 2.5e-33 115.3 16.0 2.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 PSC74384.1 - 7.6e-24 84.8 0.0 1.2e-23 84.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PSC74384.1 - 5.8e-07 28.9 12.9 1.4e-06 27.7 12.9 1.7 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PSC74384.1 - 1.8e-06 28.0 0.0 0.046 13.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 PSC74384.1 - 0.00018 21.4 0.0 0.00039 20.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 PSC74384.1 - 0.00044 19.9 0.1 0.0011 18.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mntp PF02659.15 PSC74384.1 - 0.00074 19.3 0.1 0.00074 19.3 0.1 3.1 3 1 1 4 4 4 1 Putative manganese efflux pump AAA_25 PF13481.6 PSC74384.1 - 0.0082 15.7 0.0 0.026 14.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PSC74384.1 - 0.017 15.7 0.0 0.036 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PSC74384.1 - 0.023 15.1 0.5 0.19 12.1 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 PSC74384.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 PSC74384.1 - 0.16 11.4 0.0 5.2 6.5 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain UPF0016 PF01169.19 PSC74385.1 - 1.6e-39 134.1 19.5 1.2e-21 76.8 6.7 5.8 6 1 0 7 7 5 2 Uncharacterized protein family UPF0016 ABC2_membrane PF01061.24 PSC74385.1 - 2.5e-33 115.3 16.0 2.5e-33 115.3 16.0 2.4 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 PSC74385.1 - 7.6e-24 84.8 0.0 1.2e-23 84.2 0.0 1.3 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PSC74385.1 - 5.7e-07 29.0 12.9 1.4e-06 27.7 12.9 1.7 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 PSC74385.1 - 1.8e-06 28.0 0.0 0.046 13.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 PSC74385.1 - 0.00018 21.4 0.0 0.00039 20.4 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 PSC74385.1 - 0.00044 19.9 0.1 0.0011 18.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Mntp PF02659.15 PSC74385.1 - 0.00076 19.3 0.1 0.00076 19.3 0.1 3.1 3 1 1 4 4 4 1 Putative manganese efflux pump AAA_25 PF13481.6 PSC74385.1 - 0.0077 15.8 0.0 0.026 14.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PSC74385.1 - 0.016 15.7 0.0 0.036 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PSC74385.1 - 0.022 15.1 0.5 0.19 12.1 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 PSC74385.1 - 0.15 12.3 0.0 0.35 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 PSC74385.1 - 0.16 11.4 0.0 5.1 6.5 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain Agenet PF05641.12 PSC74386.1 - 5.2e-11 42.8 2.0 1e-08 35.5 0.1 2.9 3 0 0 3 3 3 2 Agenet domain PHD PF00628.29 PSC74386.1 - 6.6e-06 25.9 4.2 1.2e-05 25.1 4.2 1.4 1 0 0 1 1 1 1 PHD-finger Myb_DNA-binding PF00249.31 PSC74386.1 - 0.00029 21.0 0.1 0.00049 20.2 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC74386.1 - 0.0021 18.3 0.0 0.005 17.1 0.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain zf-HC5HC2H_2 PF13832.6 PSC74386.1 - 0.0078 16.4 0.3 0.0078 16.4 0.3 2.0 2 0 0 2 2 2 1 PHD-zinc-finger like domain Tudor_4 PF18358.1 PSC74386.1 - 0.014 15.0 0.1 1.8 8.2 0.0 2.6 2 0 0 2 2 2 0 Histone methyltransferase Tudor domain zf-HC5HC2H PF13771.6 PSC74386.1 - 0.037 14.3 0.8 0.12 12.7 0.8 1.8 1 0 0 1 1 1 0 PHD-like zinc-binding domain SH3_9 PF14604.6 PSC74386.1 - 0.099 12.5 0.1 2.2 8.2 0.0 2.3 2 0 0 2 2 2 0 Variant SH3 domain PHD_2 PF13831.6 PSC74386.1 - 0.48 10.0 1.9 0.96 9.1 1.9 1.5 1 0 0 1 1 1 0 PHD-finger mTERF PF02536.14 PSC74387.1 - 7.6e-07 28.3 0.0 0.00021 20.3 0.0 3.1 2 1 1 4 4 4 2 mTERF PAP_central PF04928.17 PSC74388.1 - 2.3e-95 318.3 0.0 3.3e-95 317.8 0.0 1.2 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 PSC74388.1 - 1.6e-16 60.4 0.0 2e-15 56.8 0.0 2.2 1 1 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 PSC74388.1 - 1.6e-08 34.7 0.0 3.4e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Nrap_D2 PF17403.2 PSC74388.1 - 0.037 13.8 0.0 0.066 13.0 0.0 1.5 1 0 0 1 1 1 0 Nrap protein PAP/OAS-like domain AP2 PF00847.20 PSC74389.1 - 2.8e-12 46.7 3.0 5.5e-12 45.7 3.0 1.5 1 0 0 1 1 1 1 AP2 domain RWP-RK PF02042.15 PSC74389.1 - 2.3e-09 37.1 0.0 4.5e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 RWP-RK domain DUF3847 PF12958.7 PSC74390.1 - 0.0045 17.1 5.0 0.016 15.3 4.5 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF3847) UPF0242 PF06785.11 PSC74390.1 - 0.0052 16.9 4.4 0.0076 16.4 4.4 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus SCP-1 PF05483.12 PSC74390.1 - 0.0065 14.5 3.8 0.0079 14.3 3.8 1.0 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) Atg14 PF10186.9 PSC74390.1 - 0.0088 15.2 5.6 0.011 14.9 5.6 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5320 PF17253.2 PSC74390.1 - 0.009 17.1 4.3 0.013 16.5 3.2 1.9 1 1 1 2 2 2 1 Family of unknown function (DUF5320) Exonuc_VII_L PF02601.15 PSC74390.1 - 0.013 15.1 4.1 0.017 14.7 4.1 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 PSC74390.1 - 0.016 13.2 4.6 0.02 12.9 4.6 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DivIC PF04977.15 PSC74390.1 - 0.025 14.4 3.2 0.025 14.4 3.2 2.2 2 0 0 2 2 2 0 Septum formation initiator LRS4 PF10422.9 PSC74390.1 - 0.032 13.8 4.2 0.042 13.4 4.2 1.2 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 PV-1 PF06637.11 PSC74390.1 - 0.06 12.2 4.7 0.074 11.9 4.7 1.2 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Rit1_C PF17184.4 PSC74390.1 - 0.073 12.5 0.3 0.091 12.2 0.3 1.1 1 0 0 1 1 1 0 Rit1 N-terminal domain Fmp27_WPPW PF10359.9 PSC74390.1 - 0.099 11.5 5.2 0.13 11.1 5.2 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Spc24 PF08286.11 PSC74390.1 - 0.14 12.4 4.6 0.17 12.1 2.7 1.9 2 0 0 2 2 2 0 Spc24 subunit of Ndc80 FapA PF03961.13 PSC74390.1 - 0.16 10.5 2.2 0.19 10.3 2.2 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A GreA_GreB_N PF03449.15 PSC74390.1 - 0.2 11.8 6.9 0.33 11.2 2.4 2.8 2 1 1 3 3 3 0 Transcription elongation factor, N-terminal MCU PF04678.13 PSC74390.1 - 0.4 10.8 7.3 0.56 10.3 7.3 1.4 1 1 0 1 1 1 0 Mitochondrial calcium uniporter SlyX PF04102.12 PSC74390.1 - 0.42 11.3 8.8 2.2 9.0 4.5 2.4 2 0 0 2 2 2 0 SlyX DUF4140 PF13600.6 PSC74390.1 - 0.91 10.0 7.6 0.31 11.5 3.9 2.1 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Sec2p PF06428.11 PSC74390.1 - 1.2 9.2 11.5 0.48 10.4 6.1 2.2 2 0 0 2 2 2 0 GDP/GTP exchange factor Sec2p EAP30 PF04157.16 PSC74390.1 - 1.6 8.0 9.0 0.45 9.7 3.5 2.1 2 0 0 2 2 2 0 EAP30/Vps36 family YabA PF06156.13 PSC74390.1 - 1.6 9.4 5.3 0.48 11.1 2.5 1.7 2 0 0 2 2 1 0 Initiation control protein YabA T2SSM PF04612.12 PSC74390.1 - 1.9 8.5 17.1 2.6 8.1 6.6 2.1 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M TFIIA PF03153.13 PSC74390.1 - 2.2 8.2 9.0 2.7 7.9 9.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FlxA PF14282.6 PSC74390.1 - 4.6 7.3 19.7 3.8 7.6 1.6 2.4 2 1 0 2 2 2 0 FlxA-like protein DEAD PF00270.29 PSC74391.1 - 8.7e-36 123.3 0.0 1.7e-35 122.3 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC74391.1 - 4.6e-31 107.4 0.0 1.1e-30 106.2 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC74391.1 - 7.6e-08 32.5 0.0 1.6e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Upf2 PF04050.14 PSC74391.1 - 0.04 14.7 0.4 0.16 12.7 0.0 2.2 2 0 0 2 2 2 0 Up-frameshift suppressor 2 Spt20 PF12090.8 PSC74391.1 - 0.75 9.4 2.2 1.4 8.5 2.2 1.4 1 0 0 1 1 1 0 Spt20 family PP-binding PF00550.25 PSC74392.1 - 2.3e-10 40.7 0.0 3.6e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site MBOAT_2 PF13813.6 PSC74393.1 - 9.2e-13 48.3 2.9 9.6e-13 48.2 0.4 2.2 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family rve PF00665.26 PSC74394.1 - 2.4e-19 69.7 0.0 5.2e-19 68.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC74394.1 - 0.0032 17.2 0.1 0.0084 15.9 0.1 1.6 1 0 0 1 1 1 1 Integrase core domain tRNA-synt_1 PF00133.22 PSC74395.1 - 6.7e-38 130.3 0.0 2e-26 92.4 0.0 2.9 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 PSC74395.1 - 2.8e-14 52.7 0.0 1.9e-06 26.9 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 PSC74395.1 - 5.4e-14 52.4 0.0 1.1e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 PSC74395.1 - 4.9e-06 26.1 0.0 8.7e-06 25.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain Ribosomal_S7e PF01251.18 PSC74396.1 - 9.7e-80 266.7 0.2 1.1e-79 266.5 0.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Lipase_GDSL_2 PF13472.6 PSC74397.1 - 4.3e-12 46.8 0.3 9.5e-12 45.7 0.0 1.7 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 PSC74397.1 - 0.056 13.4 0.0 0.43 10.5 0.0 2.0 1 1 1 2 2 2 0 GDSL-like Lipase/Acylhydrolase LisH PF08513.11 PSC74398.1 - 0.00029 20.7 0.6 0.00078 19.3 0.1 2.1 2 0 0 2 2 2 1 LisH HEAT PF02985.22 PSC74398.1 - 0.039 14.2 7.7 0.25 11.7 1.0 5.1 3 1 1 4 4 4 0 HEAT repeat NUDIX_4 PF14815.6 PSC74398.1 - 0.12 12.4 5.9 0.48 10.4 0.1 3.8 4 0 0 4 4 4 0 NUDIX domain Pyrophosphatase PF00719.19 PSC74399.1 - 9.9e-57 191.2 0.1 1.1e-56 191.0 0.1 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase AAA_14 PF13173.6 PSC74399.1 - 0.013 15.5 0.1 0.018 15.1 0.1 1.2 1 0 0 1 1 1 0 AAA domain OAD_gamma PF04277.13 PSC74400.1 - 0.0002 21.9 0.1 0.032 14.8 0.1 2.3 2 0 0 2 2 2 1 Oxaloacetate decarboxylase, gamma chain RskA PF10099.9 PSC74400.1 - 0.002 18.4 8.6 0.0028 18.0 8.6 1.3 1 0 0 1 1 1 1 Anti-sigma-K factor rskA Ribosomal_60s PF00428.19 PSC74400.1 - 0.0045 17.5 8.2 0.0045 17.5 8.2 2.3 2 0 0 2 2 2 1 60s Acidic ribosomal protein BatD PF13584.6 PSC74400.1 - 0.0077 15.1 0.1 0.01 14.7 0.1 1.0 1 0 0 1 1 1 1 Oxygen tolerance Oxidored_q2 PF00420.24 PSC74400.1 - 0.019 14.6 0.1 0.029 14.0 0.1 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L PRIMA1 PF16101.5 PSC74400.1 - 2.2 8.4 4.7 3.9 7.5 4.7 1.5 1 1 0 1 1 1 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 PSC74400.1 - 4.7 6.6 6.3 3 7.2 2.7 1.9 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal ADK PF00406.22 PSC74401.1 - 3.2e-42 144.2 0.0 4.4e-42 143.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 PSC74401.1 - 6.5e-23 81.7 0.0 3.2e-22 79.4 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 PSC74401.1 - 7.7e-07 29.4 0.1 0.00083 19.5 0.0 2.6 2 1 1 3 3 3 2 AAA domain RIIa PF02197.17 PSC74401.1 - 0.00059 19.4 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 Regulatory subunit of type II PKA R-subunit ADK_lid PF05191.14 PSC74401.1 - 0.076 13.0 0.2 0.43 10.6 0.2 2.0 1 1 0 1 1 1 0 Adenylate kinase, active site lid PET117 PF15786.5 PSC74402.1 - 2.3e-10 40.6 0.0 2.7e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial DUF2178 PF09946.9 PSC74402.1 - 0.15 12.2 0.0 0.17 12.1 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2178) MBOAT_2 PF13813.6 PSC74403.1 - 0.0003 21.0 0.1 0.0011 19.2 0.0 2.0 2 0 0 2 2 2 1 Membrane bound O-acyl transferase family Sec7 PF01369.20 PSC74404.1 - 7.7e-60 201.7 0.0 1.2e-59 201.1 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 PSC74404.1 - 2e-15 57.0 0.0 6.4e-15 55.4 0.0 2.0 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal EF-hand_1 PF00036.32 PSC74404.1 - 1.7e-11 42.8 8.7 2.4e-06 26.7 0.2 4.6 4 0 0 4 4 4 2 EF hand EF-hand_7 PF13499.6 PSC74404.1 - 9.4e-09 35.6 2.6 0.0059 17.0 0.0 4.4 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_8 PF13833.6 PSC74404.1 - 9.5e-09 35.0 2.8 0.029 14.2 0.2 4.4 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.6 PSC74404.1 - 3e-07 29.9 3.4 6.5e-05 22.5 0.2 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 PSC74404.1 - 4.9e-05 22.6 11.9 5.9e-05 22.4 0.2 4.1 4 0 0 4 4 4 2 EF hand DCB PF16213.5 PSC74404.1 - 0.011 15.5 0.0 0.033 13.9 0.0 1.8 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 PocR PF10114.9 PSC74404.1 - 0.18 11.6 0.1 0.4 10.4 0.1 1.6 1 0 0 1 1 1 0 Sensory domain found in PocR Sec7 PF01369.20 PSC74405.1 - 7.6e-60 201.7 0.0 1.2e-59 201.1 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 PSC74405.1 - 1.7e-15 57.3 0.0 6.3e-15 55.4 0.0 2.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal EF-hand_1 PF00036.32 PSC74405.1 - 1.6e-11 42.9 8.7 2.4e-06 26.7 0.2 4.6 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 PSC74405.1 - 9.1e-09 35.0 2.8 0.029 14.2 0.2 4.4 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.6 PSC74405.1 - 9.4e-09 35.6 2.6 0.0066 16.9 0.3 4.4 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 PSC74405.1 - 2.8e-07 29.9 3.4 6.4e-05 22.6 0.2 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 PSC74405.1 - 4.7e-05 22.7 11.9 5.8e-05 22.4 0.2 4.1 4 0 0 4 4 4 2 EF hand DCB PF16213.5 PSC74405.1 - 0.01 15.5 0.0 0.032 13.9 0.0 1.8 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 PocR PF10114.9 PSC74405.1 - 0.18 11.6 0.1 0.4 10.4 0.1 1.6 1 0 0 1 1 1 0 Sensory domain found in PocR Sec7 PF01369.20 PSC74406.1 - 7.6e-60 201.7 0.0 1.2e-59 201.1 0.0 1.3 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 PSC74406.1 - 1.7e-15 57.3 0.0 6.3e-15 55.4 0.0 2.1 1 0 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal EF-hand_1 PF00036.32 PSC74406.1 - 1.6e-11 42.9 8.7 2.4e-06 26.7 0.2 4.6 4 0 0 4 4 4 2 EF hand EF-hand_8 PF13833.6 PSC74406.1 - 9e-09 35.0 2.8 0.029 14.2 0.2 4.4 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_7 PF13499.6 PSC74406.1 - 9.4e-09 35.6 2.6 0.0065 16.9 0.3 4.4 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.6 PSC74406.1 - 2.8e-07 29.9 3.4 6.4e-05 22.6 0.2 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.6 PSC74406.1 - 4.7e-05 22.7 11.9 5.8e-05 22.4 0.2 4.1 4 0 0 4 4 4 2 EF hand DCB PF16213.5 PSC74406.1 - 0.01 15.5 0.0 0.032 13.9 0.0 1.8 1 0 0 1 1 1 0 Dimerisation and cyclophilin-binding domain of Mon2 PocR PF10114.9 PSC74406.1 - 0.17 11.6 0.1 0.4 10.4 0.1 1.6 1 0 0 1 1 1 0 Sensory domain found in PocR EF-hand_1 PF00036.32 PSC74407.1 - 2.2e-16 58.1 0.0 5.8e-05 22.4 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PSC74407.1 - 4.9e-14 52.5 0.0 0.00017 21.9 0.0 3.3 2 1 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 PSC74407.1 - 5.7e-14 50.8 0.0 4.3e-05 23.1 0.0 4.3 4 0 0 4 4 4 3 EF-hand domain EF-hand_8 PF13833.6 PSC74407.1 - 1.8e-13 50.1 0.0 2.5e-09 36.8 0.0 3.9 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 PSC74407.1 - 1.3e-08 34.0 0.0 0.00012 21.4 0.0 4.0 4 0 0 4 4 4 1 EF hand EF-hand_9 PF14658.6 PSC74407.1 - 0.0042 17.4 0.0 5.6 7.4 0.0 3.3 4 0 0 4 4 4 2 EF-hand domain DUF805 PF05656.14 PSC74407.1 - 0.027 14.9 0.0 1.1 9.7 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF805) Toprim_2 PF13155.6 PSC74407.1 - 0.11 12.9 0.2 12 6.4 0.1 3.0 1 1 2 3 3 3 0 Toprim-like Diphthamide_syn PF01866.17 PSC74408.1 - 8.5e-111 370.2 0.0 1.3e-110 369.6 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein CBM_20 PF00686.19 PSC74408.1 - 1.5e-19 69.6 0.2 2.9e-19 68.8 0.2 1.4 1 0 0 1 1 1 1 Starch binding domain TMF_TATA_bd PF12325.8 PSC74408.1 - 1.7 8.9 10.8 3.9 7.7 10.8 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding YabA PF06156.13 PSC74408.1 - 3.7 8.3 5.9 11 6.7 5.9 1.8 1 1 0 1 1 1 0 Initiation control protein YabA DNA_pol_A_exo1 PF01612.20 PSC74409.1 - 2.3e-16 60.0 0.0 7.7e-14 51.8 0.0 2.3 2 0 0 2 2 2 2 3'-5' exonuclease tRNA_edit PF04073.15 PSC74409.1 - 1e-15 57.9 2.3 1.1e-15 57.8 0.0 2.2 2 0 0 2 2 2 1 Aminoacyl-tRNA editing domain HTH_8 PF02954.19 PSC74410.1 - 5 7.0 6.3 1.5 8.7 1.6 2.5 2 0 0 2 2 2 0 Bacterial regulatory protein, Fis family LysM PF01476.20 PSC74411.1 - 1.6e-39 133.7 1.3 1.3e-09 38.0 0.0 4.4 4 0 0 4 4 4 4 LysM domain Phage_tail_X PF05489.12 PSC74411.1 - 0.015 14.9 0.0 0.94 9.2 0.0 3.3 3 0 0 3 3 3 0 Phage Tail Protein X NICE-1 PF15845.5 PSC74411.1 - 0.058 14.2 0.7 0.058 14.2 0.7 4.4 3 1 0 3 3 3 0 Cysteine-rich C-terminal 1 family Ribosomal_L7Ae PF01248.26 PSC74412.1 - 5.7e-24 83.7 0.1 1.2e-23 82.6 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1524 PF07510.11 PSC74412.1 - 9.4e-22 77.4 0.0 1.7e-21 76.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1524) DUF262 PF03235.14 PSC74412.1 - 3e-10 40.7 0.0 4.8e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF262 Ank_2 PF12796.7 PSC74413.1 - 1.1e-25 90.1 0.4 8.1e-10 39.2 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PSC74413.1 - 1.1e-21 74.6 5.9 2.8e-06 27.2 0.0 6.0 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 PSC74413.1 - 5.3e-21 74.4 9.4 1.2e-07 31.9 0.0 5.3 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 PSC74413.1 - 6.3e-18 64.3 10.1 7.8e-07 29.3 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 PSC74413.1 - 2.4e-16 59.9 4.9 1.5e-06 28.6 0.1 5.4 4 2 1 6 6 6 3 Ankyrin repeats (many copies) MMtag PF10159.9 PSC74414.1 - 1.5e-26 92.5 17.0 1.7e-26 92.3 1.6 2.4 2 0 0 2 2 2 1 Multiple myeloma tumor-associated HATPase_c_3 PF13589.6 PSC74414.1 - 5e-09 36.1 0.7 1.5e-08 34.5 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 PSC74414.1 - 9.3e-06 26.1 0.2 7.5e-05 23.2 0.0 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase TFIIA PF03153.13 PSC74414.1 - 0.32 10.9 13.7 0.4 10.6 13.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AP3D1 PF06375.11 PSC74414.1 - 0.36 11.1 12.2 0.41 10.9 11.0 1.7 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 NARP1 PF12569.8 PSC74414.1 - 1 8.2 10.8 1.6 7.5 10.8 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Spt20 PF12090.8 PSC74414.1 - 1.1 8.8 12.8 1.8 8.2 12.8 1.2 1 0 0 1 1 1 0 Spt20 family DUF2229 PF09989.9 PSC74414.1 - 2.4 7.7 5.2 5.6 6.6 5.2 1.6 1 0 0 1 1 1 0 CoA enzyme activase uncharacterised domain (DUF2229) GREB1 PF15782.5 PSC74414.1 - 2.6 5.1 5.0 2.9 4.9 5.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 PSC74414.1 - 3.5 6.3 6.3 4.5 5.9 6.3 1.1 1 0 0 1 1 1 0 Presenilin MSP PF01716.18 PSC74415.1 - 5.3e-99 330.3 0.6 7.6e-99 329.8 0.6 1.2 1 0 0 1 1 1 1 Manganese-stabilising protein / photosystem II polypeptide WD40 PF00400.32 PSC74415.1 - 9.6e-21 73.7 5.7 0.0018 19.1 0.5 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat UTP15_C PF09384.10 PSC74415.1 - 2.7e-15 56.3 0.0 4.4e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 UTP15 C terminal ANAPC4_WD40 PF12894.7 PSC74415.1 - 2.3e-07 31.0 0.0 0.65 10.3 0.0 4.8 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 PSC74415.1 - 0.023 13.2 0.2 0.073 11.6 0.1 1.9 2 0 0 2 2 2 0 Cytochrome D1 heme domain DUF3263 PF11662.8 PSC74415.1 - 0.026 14.3 0.1 0.055 13.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3263) Retrotran_gag_2 PF14223.6 PSC74416.1 - 1.8e-24 86.0 0.0 2.8e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 PSC74416.1 - 6.3e-23 81.2 0.0 1.4e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 PSC74416.1 - 8.2e-09 35.2 0.0 1.6e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4219 PF13961.6 PSC74416.1 - 3e-05 23.6 0.0 6.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) rve_3 PF13683.6 PSC74416.1 - 0.0012 18.6 0.0 0.0044 16.8 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain RVT_2 PF07727.14 PSC74416.1 - 0.0096 15.6 0.1 0.015 15.0 0.1 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_3 PF13917.6 PSC74416.1 - 0.098 12.6 0.3 0.27 11.2 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 PSC74416.1 - 0.1 12.4 2.0 0.2 11.4 2.0 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger Retrotran_gag_3 PF14244.6 PSC74416.1 - 0.13 12.0 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Phage_GPD PF05954.11 PSC74416.1 - 0.15 11.3 0.3 0.3 10.3 0.3 1.4 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) Asp_protease_2 PF13650.6 PSC74416.1 - 0.17 12.5 0.0 0.43 11.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease DUF4209 PF13910.6 PSC74417.1 - 0.014 15.6 0.0 0.43 10.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4209) TFIIA PF03153.13 PSC74417.1 - 0.051 13.6 6.4 0.047 13.7 6.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 PSC74417.1 - 2.4 7.7 9.2 3.6 7.1 9.2 1.2 1 0 0 1 1 1 0 Spt20 family DUF2894 PF11445.8 PSC74417.1 - 2.5 8.5 15.5 1.2 9.6 12.1 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF2894) CCT PF06203.14 PSC74418.1 - 0.00081 19.4 0.5 0.0017 18.4 0.5 1.5 1 0 0 1 1 1 1 CCT motif FAM199X PF15814.5 PSC74418.1 - 0.082 12.0 1.1 0.13 11.3 1.1 1.3 1 0 0 1 1 1 0 Protein family FAM199X DCP1 PF06058.13 PSC74419.1 - 2.7e-39 133.7 0.0 3.6e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Dcp1-like decapping family DCP1 PF06058.13 PSC74420.1 - 2.7e-39 133.7 0.0 3.5e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Dcp1-like decapping family Guanylate_cyc PF00211.20 PSC74422.1 - 3.2e-11 43.2 0.0 4.6e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain NMN_transporter PF04973.12 PSC74422.1 - 0.079 12.9 4.8 0.13 12.2 4.8 1.3 1 0 0 1 1 1 0 Nicotinamide mononucleotide transporter ADK PF00406.22 PSC74423.1 - 1.3e-49 168.1 0.0 1.7e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 PSC74423.1 - 4.7e-27 95.1 0.0 8.7e-27 94.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PSC74423.1 - 2.3e-05 24.9 0.0 4.5e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PSC74423.1 - 0.00024 21.3 0.1 0.32 11.2 0.0 3.0 2 1 1 3 3 3 2 AAA domain Thymidylate_kin PF02223.17 PSC74423.1 - 0.0016 18.2 0.1 6.3 6.4 0.0 3.1 2 1 1 3 3 3 2 Thymidylate kinase Hydin_ADK PF17213.3 PSC74423.1 - 0.0048 17.2 0.6 0.014 15.7 0.4 1.7 1 1 0 2 2 2 1 Hydin Adenylate kinase-like domain Zeta_toxin PF06414.12 PSC74423.1 - 0.034 13.4 0.2 0.075 12.3 0.2 1.5 1 0 0 1 1 1 0 Zeta toxin ADK_lid PF05191.14 PSC74423.1 - 0.041 13.9 0.1 0.23 11.5 0.1 2.1 1 1 0 1 1 1 0 Adenylate kinase, active site lid AMPK1_CBM PF16561.5 PSC74424.1 - 6.3e-29 100.0 0.2 1.1e-28 99.2 0.2 1.4 1 0 0 1 1 1 1 Glycogen recognition site of AMP-activated protein kinase CBS PF00571.28 PSC74424.1 - 1.1e-23 83.5 0.5 9.2e-07 29.2 0.3 4.4 4 0 0 4 4 4 4 CBS domain CBM_48 PF02922.18 PSC74424.1 - 0.0002 21.6 0.0 0.00037 20.8 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) TFIIA PF03153.13 PSC74424.1 - 0.0018 18.3 10.0 0.003 17.6 10.0 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 PSC74424.1 - 5.4 6.3 8.0 9 5.5 8.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spt20 PF12090.8 PSC74424.1 - 8 6.0 20.8 16 5.0 20.8 1.4 1 0 0 1 1 1 0 Spt20 family zf-C3HC4 PF00097.25 PSC74426.1 - 4.4e-07 29.7 8.2 4.4e-07 29.7 8.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PSC74426.1 - 1.1e-06 28.4 7.7 1.1e-06 28.4 7.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC74426.1 - 1.2e-06 28.4 7.8 1.2e-06 28.4 7.8 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 PSC74426.1 - 5e-06 26.4 7.3 5e-06 26.4 7.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.6 PSC74426.1 - 1.2e-05 25.6 8.0 1.2e-05 25.6 8.0 2.2 2 0 0 2 2 2 1 Ring finger domain SAP PF02037.27 PSC74426.1 - 0.00024 20.8 0.1 0.00052 19.7 0.1 1.5 1 0 0 1 1 1 1 SAP domain zf-C3HC4_3 PF13920.6 PSC74426.1 - 0.00036 20.3 12.5 0.00061 19.6 8.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-WRNIP1_ubi PF18279.1 PSC74426.1 - 0.0039 17.7 0.1 0.0039 17.7 0.1 3.0 3 0 0 3 3 1 1 Werner helicase-interacting protein 1 ubiquitin-binding domain zf-rbx1 PF12678.7 PSC74426.1 - 0.012 15.8 2.9 0.012 15.8 2.9 2.1 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 PSC74426.1 - 0.015 15.4 2.9 0.038 14.1 2.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 PSC74426.1 - 0.06 13.2 14.4 0.088 12.7 9.3 2.5 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 UBZ_FAAP20 PF15750.5 PSC74426.1 - 0.093 12.7 0.0 0.093 12.7 0.0 2.2 2 0 0 2 2 1 0 Ubiquitin-binding zinc-finger zf-RING_10 PF16685.5 PSC74426.1 - 0.58 10.3 5.5 1.6 8.9 5.5 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 PSC74426.1 - 1.2 9.3 15.2 0.26 11.5 10.4 2.2 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 PSC74426.1 - 2.2 8.2 8.8 0.3 11.0 3.2 2.1 2 0 0 2 2 2 0 zf-RING of BARD1-type protein MFS_1 PF07690.16 PSC74427.1 - 9.1e-34 116.9 29.3 9.1e-34 116.9 29.3 2.5 2 1 0 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 PSC74427.1 - 2.2e-07 30.1 15.6 4.7e-06 25.7 6.8 2.6 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_1_like PF12832.7 PSC74427.1 - 0.25 10.1 4.7 1.2 7.9 0.0 2.6 2 1 1 3 3 3 0 MFS_1 like family PTR2 PF00854.21 PSC74427.1 - 7.4 5.3 10.9 0.032 13.1 1.7 1.6 2 0 0 2 2 2 0 POT family Cpn60_TCP1 PF00118.24 PSC74428.1 - 2.9e-149 497.8 10.6 3.6e-149 497.6 10.6 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DnaJ PF00226.31 PSC74428.1 - 2.6e-23 81.9 0.6 6.4e-23 80.7 0.6 1.7 1 0 0 1 1 1 1 DnaJ domain DUF1977 PF09320.11 PSC74428.1 - 2.1e-18 66.5 1.3 2.1e-18 66.5 1.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1977) TPR_14 PF13428.6 PSC74428.1 - 1.7 9.7 8.6 1.9 9.5 1.4 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 PSC74428.1 - 1.8 8.9 5.4 0.84 9.9 0.3 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Ribosomal_S3_C PF00189.20 PSC74429.1 - 6.4e-24 84.3 2.5 8.5e-24 83.9 0.4 2.2 2 1 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 PSC74429.1 - 5.4e-12 45.4 0.3 8.7e-12 44.7 0.3 1.4 1 0 0 1 1 1 1 KH domain A_deamin PF02137.18 PSC74430.1 - 3.9e-50 171.2 0.2 3.6e-28 99.0 0.0 4.4 4 1 1 5 5 5 3 Adenosine-deaminase (editase) domain Cas3_C PF18395.1 PSC74430.1 - 0.12 12.9 0.4 8.6 6.9 0.2 3.0 2 0 0 2 2 2 0 Cas3 C-terminal domain MIF4G PF02854.19 PSC74431.1 - 1.3e-42 145.8 0.4 5.4e-42 143.8 0.4 1.9 1 1 0 1 1 1 1 MIF4G domain MA3 PF02847.17 PSC74431.1 - 1.3e-10 41.2 0.0 4.1e-10 39.6 0.0 1.9 1 0 0 1 1 1 1 MA3 domain CNOT1_CAF1_bind PF16415.5 PSC74431.1 - 0.0097 15.3 0.0 0.021 14.2 0.0 1.4 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain TFIID-31kDa PF02291.15 PSC74432.1 - 7.1e-22 77.8 0.0 2.1e-21 76.3 0.0 1.7 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit ARS2 PF04959.13 PSC74432.1 - 1 9.7 6.3 1.7 9.0 6.3 1.3 1 0 0 1 1 1 0 Arsenite-resistance protein 2 Glycolytic PF00274.19 PSC74433.1 - 7.7e-155 514.9 0.0 8.9e-155 514.7 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I SUI1 PF01253.22 PSC74434.1 - 1e-22 80.5 0.2 2.2e-22 79.4 0.2 1.5 1 0 0 1 1 1 1 Translation initiation factor SUI1 zf-MYND PF01753.18 PSC74434.1 - 7.6e-07 29.1 9.6 2.1e-06 27.7 9.6 1.8 1 0 0 1 1 1 1 MYND finger Ank_2 PF12796.7 PSC74435.1 - 6.6e-48 161.2 20.4 2.2e-15 57.0 0.1 5.8 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Peptidase_S8 PF00082.22 PSC74435.1 - 3.1e-35 121.9 1.1 3.1e-35 121.9 1.1 2.0 1 1 0 2 2 2 1 Subtilase family Ank_4 PF13637.6 PSC74435.1 - 2.1e-34 117.4 27.3 7.4e-10 39.2 0.4 5.7 3 2 4 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC74435.1 - 1.3e-33 114.6 22.3 2.2e-08 34.2 0.6 8.5 3 2 6 9 9 9 8 Ankyrin repeats (many copies) Ank PF00023.30 PSC74435.1 - 2.2e-30 103.7 40.0 2.4e-06 27.7 0.0 9.3 8 1 1 9 9 9 6 Ankyrin repeat Ank_3 PF13606.6 PSC74435.1 - 5.6e-27 90.8 21.0 2.3e-05 24.4 0.1 9.9 9 1 1 10 10 10 7 Ankyrin repeat LysM PF01476.20 PSC74436.1 - 1.6e-28 98.4 0.0 3.2e-07 30.3 0.0 5.0 5 1 0 5 5 5 4 LysM domain Bax1-I PF01027.20 PSC74437.1 - 0.04 13.7 9.4 0.056 13.3 9.4 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Amidase PF01425.21 PSC74438.1 - 1.4e-156 522.0 0.6 1.9e-156 521.6 0.6 1.2 1 0 0 1 1 1 1 Amidase WD40 PF00400.32 PSC74438.1 - 5e-18 65.1 13.1 0.0038 18.0 0.5 6.6 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.11 PSC74438.1 - 1.8e-06 28.0 0.0 0.015 15.2 0.0 3.4 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 PSC74438.1 - 0.00037 20.7 0.0 2.6 8.4 0.0 3.9 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PSC74438.1 - 0.002 16.8 0.2 0.032 12.9 0.0 2.5 2 1 1 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 PSC74438.1 - 0.15 10.8 0.0 0.34 9.6 0.0 1.5 1 1 0 1 1 1 0 Nup133 N terminal like Tom22 PF04281.13 PSC74439.1 - 1.1e-09 38.1 0.1 1.2e-09 38.0 0.1 1.0 1 0 0 1 1 1 1 Mitochondrial import receptor subunit Tom22 Filamin PF00630.19 PSC74440.1 - 4.5e-06 27.4 0.0 8.2e-06 26.6 0.0 1.3 1 0 0 1 1 1 1 Filamin/ABP280 repeat p25-alpha PF05517.12 PSC74441.1 - 3.5e-13 50.0 0.0 4.4e-12 46.4 0.0 2.6 3 1 0 3 3 3 1 p25-alpha EF-hand_6 PF13405.6 PSC74441.1 - 0.052 13.5 0.0 0.61 10.2 0.0 2.6 2 0 0 2 2 2 0 EF-hand domain Nup54 PF13874.6 PSC74442.1 - 0.0008 19.5 5.2 0.0008 19.5 5.2 6.4 4 2 3 7 7 7 2 Nucleoporin complex subunit 54 ParD_antitoxin PF03693.14 PSC74442.1 - 0.16 12.4 8.2 0.23 11.9 0.4 3.6 3 0 0 3 3 3 0 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH TCR PF03638.15 PSC74443.1 - 8.7e-21 74.0 39.2 3.3e-12 46.5 23.0 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain NAD_binding_10 PF13460.6 PSC74444.1 - 3.8e-33 114.9 0.6 5.8e-33 114.3 0.6 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 PSC74444.1 - 5.6e-06 26.0 0.2 9.6e-06 25.2 0.0 1.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 PSC74444.1 - 0.00018 21.2 0.1 0.00035 20.2 0.1 1.5 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 PSC74444.1 - 0.00054 19.1 0.3 0.00079 18.5 0.3 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AlaDh_PNT_C PF01262.21 PSC74444.1 - 0.0006 19.2 0.6 0.00097 18.5 0.6 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_7 PF13241.6 PSC74444.1 - 0.0058 17.0 0.5 0.027 14.9 0.5 2.1 1 1 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.18 PSC74444.1 - 0.0061 16.8 1.9 0.0074 16.5 0.5 1.8 2 0 0 2 2 2 1 TrkA-N domain HIM1 PF08732.10 PSC74444.1 - 0.0066 16.0 0.0 0.016 14.8 0.0 1.6 1 1 0 1 1 1 1 HIM1 DSPc PF00782.20 PSC74445.1 - 8.9e-28 96.8 0.0 1.3e-27 96.2 0.0 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Act-Frag_cataly PF09192.10 PSC74445.1 - 2.4e-11 43.6 0.0 3.7e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Actin-fragmin kinase, catalytic Init_tRNA_PT PF04179.12 PSC74445.1 - 0.062 13.6 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Rit1 DUSP-like domain Y_phosphatase PF00102.27 PSC74445.1 - 0.14 11.7 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Tcp11 PF05794.13 PSC74446.1 - 2e-39 136.0 0.0 5.7e-39 134.5 0.0 1.7 1 1 0 1 1 1 1 T-complex protein 11 HD_4 PF13328.6 PSC74447.1 - 6.9e-73 243.5 4.3 1.9e-35 121.9 4.7 3.0 2 1 0 2 2 2 2 HD domain RelA_SpoT PF04607.17 PSC74447.1 - 2.7e-45 153.4 0.0 5.4e-26 91.2 0.0 3.5 3 1 0 3 3 3 2 Region found in RelA / SpoT proteins TGS PF02824.21 PSC74447.1 - 2.5e-21 75.5 3.2 1.1e-19 70.2 0.1 3.1 3 0 0 3 3 3 1 TGS domain HD PF01966.22 PSC74447.1 - 6.1e-14 52.3 1.0 5.1e-06 26.7 0.1 2.8 2 0 0 2 2 2 2 HD domain ACT_4 PF13291.6 PSC74447.1 - 7.2e-05 23.3 0.0 0.00017 22.1 0.0 1.6 1 0 0 1 1 1 1 ACT domain ACT PF01842.25 PSC74447.1 - 0.0002 21.0 0.0 0.00064 19.4 0.0 1.9 1 0 0 1 1 1 1 ACT domain HDOD PF08668.12 PSC74447.1 - 0.031 13.8 1.0 0.098 12.1 0.0 2.2 3 0 0 3 3 3 0 HDOD domain LRR_6 PF13516.6 PSC74449.1 - 2.8e-07 30.0 0.6 1.8e-05 24.4 0.2 2.9 2 0 0 2 2 2 1 Leucine Rich repeat LRR_4 PF12799.7 PSC74449.1 - 0.02 15.3 0.0 0.051 14.0 0.0 1.7 1 0 0 1 1 1 0 Leucine Rich repeats (2 copies) TFIIF_alpha PF05793.12 PSC74449.1 - 0.34 9.5 8.8 0.67 8.5 8.8 1.4 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CCDC106 PF15794.5 PSC74449.1 - 7.4 6.2 6.5 15 5.2 6.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 106 rve PF00665.26 PSC74450.1 - 8.4e-19 67.9 0.0 1.8e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC74450.1 - 0.0066 16.2 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain HC2 PF07382.11 PSC74451.1 - 4.6e-06 26.8 104.6 2.5e-05 24.5 104.6 2.0 1 1 0 1 1 1 1 Histone H1-like nucleoprotein HC2 Ribosomal_L29 PF00831.23 PSC74452.1 - 1.3e-09 37.9 0.2 2e-09 37.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal L29 protein DUF677 PF05055.12 PSC74453.1 - 0.042 12.7 1.1 0.062 12.2 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) CCDC-167 PF15188.6 PSC74453.1 - 0.053 13.9 1.5 0.14 12.5 1.5 1.6 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF3275 PF11679.8 PSC74453.1 - 0.27 11.2 5.7 4.7 7.1 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3275) Macoilin PF09726.9 PSC74453.1 - 3.3 6.2 11.6 5.3 5.5 11.6 1.2 1 0 0 1 1 1 0 Macoilin family Pkinase PF00069.25 PSC74454.1 - 9e-66 221.9 0.0 1.1e-65 221.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74454.1 - 2e-28 99.4 0.0 2.8e-28 98.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC74454.1 - 0.017 14.5 0.0 0.32 10.3 0.0 2.1 2 0 0 2 2 2 0 Kinase-like DUF4404 PF14357.6 PSC74454.1 - 0.54 10.9 1.9 1.4 9.6 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4404) Transglut_core2 PF13369.6 PSC74455.1 - 9.7e-06 25.2 0.0 7.2e-05 22.4 0.0 2.1 2 0 0 2 2 2 1 Transglutaminase-like superfamily REV1_C PF16727.5 PSC74456.1 - 0.085 13.3 0.2 1.6 9.2 0.0 2.8 2 0 0 2 2 2 0 DNA repair protein REV1 C-terminal domain Glyco_hydro_47 PF01532.20 PSC74457.1 - 1.2e-128 430.0 0.0 6.9e-84 282.4 0.0 4.4 3 1 1 4 4 4 4 Glycosyl hydrolase family 47 Hemerythrin PF01814.23 PSC74457.1 - 1.1e-07 32.5 5.1 1.1e-07 32.5 5.1 3.2 3 1 0 3 3 3 1 Hemerythrin HHE cation binding domain PPP4R2 PF09184.11 PSC74457.1 - 0.68 9.5 23.3 0.024 14.3 13.9 2.3 2 0 0 2 2 2 0 PPP4R2 RNase_H2_suC PF08615.11 PSC74457.1 - 2.3 8.4 11.9 10 6.3 0.0 3.2 3 0 0 3 3 3 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SpoIIP PF07454.11 PSC74457.1 - 3.1 7.2 21.9 1.3 8.4 0.7 3.3 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) RNA_polI_A34 PF08208.11 PSC74457.1 - 4.1 7.4 17.0 18 5.4 10.5 3.2 3 0 0 3 3 3 0 DNA-directed RNA polymerase I subunit RPA34.5 EOS1 PF12326.8 PSC74457.1 - 10 6.0 5.5 8.1 6.3 0.1 2.8 3 0 0 3 3 3 0 N-glycosylation protein Polysacc_deac_1 PF01522.21 PSC74458.1 - 1.8e-07 31.1 0.0 5.8e-07 29.5 0.0 2.0 1 0 0 1 1 1 1 Polysaccharide deacetylase Insulin_TMD PF17870.1 PSC74458.1 - 0.0042 17.1 0.4 0.019 15.0 0.0 2.2 2 0 0 2 2 2 1 Insulin receptor trans-membrane segment Ribosomal_60s PF00428.19 PSC74458.1 - 1.1 9.9 7.7 2 9.1 0.1 2.7 2 0 0 2 2 2 0 60s Acidic ribosomal protein Glycos_transf_2 PF00535.26 PSC74459.1 - 3.6e-23 82.2 0.0 4.5e-22 78.6 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PSC74459.1 - 7.2e-10 39.1 0.0 1.6e-09 38.0 0.0 1.7 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 PSC74459.1 - 0.003 17.1 0.0 0.004 16.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 PSC74459.1 - 0.077 13.5 0.0 0.21 12.2 0.0 1.8 2 0 0 2 2 2 0 Glycosyl transferase family 2 Pribosyltran PF00156.27 PSC74459.1 - 0.091 12.3 0.0 1.4 8.4 0.0 2.2 2 0 0 2 2 2 0 Phosphoribosyl transferase domain ketoacyl-synt PF00109.26 PSC74460.1 - 5.5e-55 186.7 0.7 1.1e-54 185.7 0.2 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 PSC74460.1 - 1.2e-31 109.1 0.9 2.6e-31 108.1 0.9 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 PSC74460.1 - 0.00013 21.5 0.4 0.00076 18.9 0.2 2.2 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 PSC74460.1 - 0.011 15.4 0.3 0.055 13.1 0.1 2.2 2 0 0 2 2 2 0 Thiolase, C-terminal domain ACP_syn_III PF08545.10 PSC74460.1 - 0.012 15.5 0.2 1.3 8.9 0.2 2.8 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III TerB PF05099.13 PSC74460.1 - 0.11 12.4 0.0 0.26 11.3 0.0 1.5 1 0 0 1 1 1 0 Tellurite resistance protein TerB RRM_1 PF00076.22 PSC74461.1 - 1e-16 60.5 0.1 1.4e-16 60.1 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PSC74461.1 - 2.9e-07 30.1 0.0 3.9e-07 29.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PSC74461.1 - 0.00017 21.6 0.0 0.00027 20.9 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif Smr PF01713.21 PSC74463.1 - 1.8e-05 25.0 0.2 4.4e-05 23.8 0.2 1.6 1 0 0 1 1 1 1 Smr domain Ribosomal_L5e PF17144.4 PSC74465.1 - 7.4e-85 282.9 0.7 7.4e-85 282.9 0.7 1.7 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 PSC74465.1 - 9.7e-34 116.2 4.4 9.7e-34 116.2 4.4 1.6 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Profilin PF00235.19 PSC74466.1 - 1.8e-41 141.4 0.0 2e-41 141.2 0.0 1.0 1 0 0 1 1 1 1 Profilin Mpt_N PF09176.11 PSC74466.1 - 0.011 15.9 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal Metallophos PF00149.28 PSC74467.1 - 9.9e-42 143.8 0.0 1.8e-41 142.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 PSC74467.1 - 3.1e-21 75.5 0.4 6.9e-21 74.4 0.4 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain WD40 PF00400.32 PSC74467.1 - 6.5e-10 39.4 7.2 0.00062 20.5 0.0 6.3 5 1 1 6 6 6 3 WD domain, G-beta repeat PQQ_2 PF13360.6 PSC74467.1 - 3.5e-08 33.3 9.9 5.3e-06 26.2 0.4 3.9 2 2 0 3 3 3 2 PQQ-like domain ANAPC4_WD40 PF12894.7 PSC74467.1 - 7.9e-08 32.5 0.0 0.013 15.7 0.0 4.6 4 2 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.21 PSC74467.1 - 0.00011 22.0 0.9 1.9 8.6 0.0 5.6 5 1 1 6 6 6 1 PQQ enzyme repeat PQQ_3 PF13570.6 PSC74467.1 - 0.0015 18.9 11.4 0.39 11.3 0.1 5.9 5 0 0 5 5 5 1 PQQ-like domain Patatin PF01734.22 PSC74468.1 - 1.8e-12 47.8 7.2 2.2e-07 31.3 2.3 2.3 2 0 0 2 2 2 2 Patatin-like phospholipase Linker_histone PF00538.19 PSC74469.1 - 8.6e-14 51.7 0.3 2.7e-13 50.1 0.3 1.9 1 0 0 1 1 1 1 linker histone H1 and H5 family Ribosomal_L18 PF17135.4 PSC74470.1 - 1.8e-94 314.5 0.7 2.4e-94 314.0 0.7 1.2 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e RmlD_sub_bind PF04321.17 PSC74470.1 - 3.4e-73 246.3 0.0 3.5e-36 124.8 0.0 2.1 1 1 1 2 2 2 2 RmlD substrate binding domain Epimerase PF01370.21 PSC74470.1 - 5.4e-42 143.9 0.0 3.4e-22 79.1 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PSC74470.1 - 4.8e-16 59.1 0.0 6.8e-07 29.0 0.0 2.4 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 PSC74470.1 - 7.5e-05 22.0 0.0 1.3 8.2 0.0 3.5 3 1 0 3 3 3 2 Male sterility protein Ribosomal_L27A PF00828.19 PSC74470.1 - 0.055 14.1 0.0 0.19 12.4 0.0 1.8 1 1 0 1 1 1 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A SNARE_assoc PF09335.11 PSC74471.1 - 2.6e-22 79.5 9.6 2.6e-22 79.5 9.6 2.1 2 0 0 2 2 2 1 SNARE associated Golgi protein p12I PF12233.8 PSC74471.1 - 0.27 11.7 2.7 0.68 10.5 0.1 2.3 2 0 0 2 2 2 0 Human adult T cell leukemia/lymphoma virus protein rve PF00665.26 PSC74472.1 - 7.6e-19 68.1 0.0 3.1e-18 66.1 0.0 2.0 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 PSC74472.1 - 0.011 15.5 0.0 0.03 14.1 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain SHMT PF00464.19 PSC74475.1 - 6.5e-200 663.8 0.0 7.7e-200 663.6 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 PSC74475.1 - 0.00018 20.8 0.0 0.0029 16.9 0.0 2.4 1 1 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 PSC74475.1 - 0.0083 15.4 0.0 0.022 14.0 0.0 1.7 1 1 0 1 1 1 1 Beta-eliminating lyase DUF4746 PF15928.5 PSC74476.1 - 0.44 9.9 6.2 0.64 9.4 6.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) GREB1 PF15782.5 PSC74476.1 - 2.4 5.2 6.3 2.9 4.9 6.3 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Neur_chan_memb PF02932.16 PSC74476.1 - 4.4 7.3 4.8 7.2 6.6 4.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 PSC74476.1 - 5.5 5.7 11.6 9.2 4.9 11.6 1.3 1 0 0 1 1 1 0 Presenilin TTSSLRR PF12468.8 PSC74477.1 - 0.13 12.5 0.0 0.13 12.5 0.0 1.2 1 0 0 1 1 1 0 Type III secretion system leucine rich repeat protein HHH_6 PF14579.6 PSC74478.1 - 0.17 12.1 0.6 0.86 9.9 0.7 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix motif PA14 PF07691.12 PSC74479.1 - 9.6e-15 54.7 0.0 1.3e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 PA14 domain GLEYA PF10528.9 PSC74479.1 - 0.023 15.1 0.0 0.12 12.8 0.0 2.0 1 1 0 1 1 1 0 GLEYA domain Ank_2 PF12796.7 PSC74480.1 - 0.016 15.8 0.0 1.3 9.6 0.0 3.4 2 2 1 3 3 3 0 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC74480.1 - 0.047 14.0 1.1 20 5.6 0.0 3.8 4 0 0 4 4 4 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC74480.1 - 0.055 14.0 1.0 2.6 8.9 0.0 4.2 4 1 0 4 4 4 0 Ankyrin repeat Ank PF00023.30 PSC74480.1 - 0.26 11.8 0.0 0.26 11.8 0.0 5.1 6 0 0 6 6 6 0 Ankyrin repeat Utp12 PF04003.12 PSC74482.1 - 0.0061 16.8 0.2 0.011 16.1 0.2 1.5 1 1 0 1 1 1 1 Dip2/Utp12 Family DUF3549 PF12069.8 PSC74482.1 - 0.055 12.5 0.1 0.14 11.2 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3549) Prefoldin PF02996.17 PSC74483.1 - 0.00035 20.5 0.0 0.00073 19.4 0.0 1.5 1 0 0 1 1 1 1 Prefoldin subunit VSP PF03302.13 PSC74483.1 - 0.59 8.9 63.0 4.1 6.1 5.9 3.7 1 1 2 3 3 3 0 Giardia variant-specific surface protein APS_kinase PF01583.20 PSC74484.1 - 5e-71 237.7 0.0 7.1e-71 237.2 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase CbiA PF01656.23 PSC74484.1 - 1.8e-06 28.0 0.0 2.6e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_33 PF13671.6 PSC74484.1 - 1.5e-05 25.2 0.0 3e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.10 PSC74484.1 - 0.00025 20.6 0.0 0.00028 20.4 0.0 1.2 1 0 0 1 1 1 1 Chromatin associated protein KTI12 ParA PF10609.9 PSC74484.1 - 0.00039 20.0 0.0 0.00058 19.4 0.0 1.2 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase SRP54 PF00448.22 PSC74484.1 - 0.0018 18.0 0.1 0.0035 17.0 0.0 1.5 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_30 PF13604.6 PSC74484.1 - 0.0026 17.5 1.3 0.0069 16.1 0.0 2.2 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 PSC74484.1 - 0.0027 18.2 0.0 0.0037 17.8 0.0 1.3 1 1 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.12 PSC74484.1 - 0.0034 16.7 0.0 0.0096 15.2 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.6 PSC74484.1 - 0.005 17.2 0.0 0.0084 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 PSC74484.1 - 0.0066 17.0 0.0 0.013 16.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 PSC74484.1 - 0.021 14.4 0.0 0.039 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArsA_ATPase PF02374.15 PSC74484.1 - 0.021 14.0 0.0 0.033 13.4 0.0 1.3 1 0 0 1 1 1 0 Anion-transporting ATPase Thymidylate_kin PF02223.17 PSC74484.1 - 0.03 14.0 0.0 0.051 13.3 0.0 1.4 1 0 0 1 1 1 0 Thymidylate kinase AAA_29 PF13555.6 PSC74484.1 - 0.036 13.8 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SWI2_SNF2 PF18766.1 PSC74484.1 - 0.045 13.4 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 SWI2/SNF2 ATPase MeaB PF03308.16 PSC74484.1 - 0.054 12.5 0.1 0.096 11.7 0.1 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 PSC74484.1 - 0.058 13.3 0.1 0.097 12.6 0.1 1.4 1 0 0 1 1 1 0 NACHT domain PRK PF00485.18 PSC74484.1 - 0.065 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family RNA_helicase PF00910.22 PSC74484.1 - 0.079 13.4 0.0 0.19 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA helicase AAA_31 PF13614.6 PSC74484.1 - 0.081 12.8 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain CLP1_P PF16575.5 PSC74484.1 - 0.17 11.6 0.0 0.28 11.0 0.0 1.3 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop RNase_Zc3h12a PF11977.8 PSC74484.1 - 0.18 11.6 0.0 0.37 10.6 0.0 1.5 2 0 0 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain RRM_1 PF00076.22 PSC74485.1 - 1.1e-10 41.1 0.0 0.0051 16.6 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SelP_N PF04592.14 PSC74485.1 - 0.019 14.4 10.9 0.03 13.7 10.9 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Helicase_C PF00271.31 PSC74486.1 - 5.4e-16 58.9 0.0 1e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PSC74486.1 - 2.2e-15 56.9 0.0 4.1e-15 56.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 PSC74486.1 - 1.1e-12 48.5 3.6 3.2e-12 47.0 3.6 1.9 1 0 0 1 1 1 1 RecQ zinc-binding AAA PF00004.29 PSC74486.1 - 9.9e-10 39.0 0.0 4.1e-09 37.0 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Rhodanese PF00581.20 PSC74486.1 - 1.1e-05 25.8 0.6 0.00061 20.3 0.1 3.5 3 1 0 3 3 3 1 Rhodanese-like domain AAA_22 PF13401.6 PSC74486.1 - 0.043 14.1 0.1 16 5.7 0.0 2.9 2 0 0 2 2 2 0 AAA domain DBI_PRT PF02277.17 PSC74487.1 - 7.2e-97 324.6 29.0 9.2e-97 324.2 29.0 1.0 1 0 0 1 1 1 1 Phosphoribosyltransferase Mtd_N PF18454.1 PSC74487.1 - 0.062 13.3 0.2 0.31 11.1 0.0 2.2 2 0 0 2 2 2 0 Major tropism determinant N-terminal domain AAA_16 PF13191.6 PSC74487.1 - 0.17 12.3 1.0 0.29 11.5 0.7 1.8 1 1 1 2 2 2 0 AAA ATPase domain DBI_PRT PF02277.17 PSC74488.1 - 5.6e-97 324.9 33.3 2.6e-51 174.8 7.4 2.0 1 1 1 2 2 2 2 Phosphoribosyltransferase Mtd_N PF18454.1 PSC74488.1 - 0.069 13.2 0.2 0.34 11.0 0.0 2.3 2 0 0 2 2 2 0 Major tropism determinant N-terminal domain AAA_16 PF13191.6 PSC74488.1 - 0.12 12.8 0.7 0.22 11.9 0.4 1.8 1 1 0 1 1 1 0 AAA ATPase domain SMN PF06003.12 PSC74490.1 - 1.8e-09 37.2 3.6 6.3e-09 35.5 0.0 2.1 1 1 0 2 2 2 1 Survival motor neuron protein (SMN) TUDOR PF00567.24 PSC74490.1 - 0.00014 21.8 0.0 0.00054 20.0 0.0 1.8 1 1 1 2 2 2 1 Tudor domain SbcD_C PF12320.8 PSC74490.1 - 0.0035 17.6 2.7 0.17 12.2 0.1 2.3 2 0 0 2 2 2 2 Type 5 capsule protein repressor C-terminal domain LRR_6 PF13516.6 PSC74491.1 - 2e-10 39.9 19.1 0.015 15.3 0.0 9.1 10 0 0 10 10 10 4 Leucine Rich repeat Thioredoxin PF00085.20 PSC74492.1 - 1.9e-18 66.3 0.0 3.5e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin DPM3 PF08285.11 PSC74492.1 - 5.6e-18 64.9 1.2 5.6e-18 64.9 1.2 1.8 2 0 0 2 2 2 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) PUB PF09409.10 PSC74492.1 - 2.5e-15 56.2 0.0 4e-15 55.5 0.0 1.3 1 0 0 1 1 1 1 PUB domain Thioredoxin_7 PF13899.6 PSC74492.1 - 2.3e-05 24.5 0.0 8.3e-05 22.7 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 PSC74492.1 - 0.00069 20.0 0.0 0.0013 19.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PSC74492.1 - 0.0034 17.7 0.0 0.006 16.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 PSC74492.1 - 0.0056 16.6 0.0 0.0099 15.8 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_9 PF14595.6 PSC74492.1 - 0.012 15.4 0.0 0.02 14.6 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin TraF PF13728.6 PSC74492.1 - 0.052 13.4 0.0 0.052 13.4 0.0 1.8 2 0 0 2 2 2 0 F plasmid transfer operon protein SAP130_C PF16014.5 PSC74492.1 - 5.8 5.9 13.8 10 5.1 13.8 1.3 1 0 0 1 1 1 0 Histone deacetylase complex subunit SAP130 C-terminus C4bp_oligo PF18453.1 PSC74493.1 - 0.014 15.6 0.1 63 3.9 0.0 3.3 3 0 0 3 3 3 0 Oligomerization domain of C4b-binding protein alpha DUF2866 PF11065.8 PSC74493.1 - 0.024 14.7 14.3 8.1 6.6 0.2 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2866) TAF PF02969.17 PSC74493.1 - 1.2 9.3 6.5 76 3.6 0.1 4.3 4 0 0 4 4 4 0 TATA box binding protein associated factor (TAF) LppA PF16708.5 PSC74493.1 - 2 8.3 28.9 7 6.6 2.6 4.3 1 1 3 4 4 4 0 Lipoprotein confined to pathogenic Mycobacterium zf-MYND PF01753.18 PSC74494.1 - 1.9e-06 27.9 13.4 5.2e-06 26.4 13.4 1.8 1 0 0 1 1 1 1 MYND finger Urb2 PF10441.9 PSC74494.1 - 0.1 12.5 4.6 2.2 8.1 4.6 2.7 1 1 0 1 1 1 0 Urb2/Npa2 family SUIM_assoc PF16619.5 PSC74494.1 - 0.7 10.0 11.5 3.8 7.7 2.5 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 zf-C6H2 PF15801.5 PSC74494.1 - 2.3 8.6 11.7 1.4 9.2 9.2 2.0 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Pkinase PF00069.25 PSC74495.1 - 3.4e-45 154.5 0.0 5.3e-45 153.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74495.1 - 1.2e-12 47.7 0.0 2e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Spt20 PF12090.8 PSC74495.1 - 5.9 6.4 8.7 8.3 6.0 8.7 1.2 1 0 0 1 1 1 0 Spt20 family dCMP_cyt_deam_1 PF00383.23 PSC74496.1 - 7.9e-09 35.3 6.3 1.1e-06 28.5 6.3 2.3 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 PSC74496.1 - 1.6e-06 27.9 1.8 0.00016 21.4 0.0 2.3 2 0 0 2 2 2 2 MafB19-like deaminase BPD_transp_1 PF00528.22 PSC74497.1 - 1.2e-13 51.2 14.9 1.2e-13 51.2 14.9 2.1 1 1 1 2 2 2 1 Binding-protein-dependent transport system inner membrane component Nucleos_tra2_C PF07662.13 PSC74497.1 - 0.013 15.4 0.9 0.013 15.4 0.9 2.0 2 0 0 2 2 2 0 Na+ dependent nucleoside transporter C-terminus DUF2713 PF10897.8 PSC74497.1 - 0.095 12.3 0.0 0.15 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2713) OAD_gamma PF04277.13 PSC74497.1 - 0.1 13.2 0.8 0.1 13.2 0.8 2.6 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain Clat_adaptor_s PF01217.20 PSC74498.1 - 3.2e-56 189.2 2.0 4e-56 188.9 2.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Nitrophorin PF02087.15 PSC74498.1 - 0.021 14.8 0.0 0.038 14.0 0.0 1.4 1 0 0 1 1 1 0 Nitrophorin Tctex-1 PF03645.13 PSC74499.1 - 3.3e-22 78.7 0.0 4.2e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family Peptidase_M14 PF00246.24 PSC74500.1 - 7.6e-60 203.1 0.1 9.6e-60 202.8 0.1 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 PSC74500.1 - 0.00033 20.9 0.4 0.00074 19.7 0.4 1.6 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain Y_Y_Y PF07495.13 PSC74500.1 - 0.03 14.3 0.0 0.072 13.0 0.0 1.6 1 0 0 1 1 1 0 Y_Y_Y domain RIO1 PF01163.22 PSC74501.1 - 2.4e-46 157.7 0.1 1.1e-45 155.5 0.0 1.9 2 0 0 2 2 2 1 RIO1 family Rio2_N PF09202.11 PSC74501.1 - 1.6e-13 50.7 1.0 3.7e-13 49.5 1.0 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 PSC74501.1 - 3.4e-07 30.4 3.9 0.0043 17.0 0.0 3.1 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 PSC74501.1 - 9.2e-05 21.9 0.0 0.0007 19.0 0.0 2.1 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 PSC74501.1 - 0.018 14.4 0.0 0.39 10.0 0.0 2.2 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.25 PSC74501.1 - 0.037 13.4 1.9 0.16 11.3 0.1 2.4 2 1 0 2 2 2 0 Protein kinase domain Choline_kinase PF01633.20 PSC74501.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase LAP1C PF05609.12 PSC74501.1 - 4.7 6.2 11.2 6.3 5.8 11.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) UCH PF00443.29 PSC74502.1 - 2.5e-47 161.5 0.0 3.5e-47 161.1 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PSC74502.1 - 1.2e-16 61.3 0.0 3e-07 30.3 0.0 3.2 2 2 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 PSC74502.1 - 0.047 13.2 2.6 0.49 9.8 0.1 2.9 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Copper-fist PF00649.18 PSC74502.1 - 0.05 13.1 0.4 0.11 12.0 0.4 1.5 1 0 0 1 1 1 0 Copper fist DNA binding domain zf-C2H2_jaz PF12171.8 PSC74503.1 - 1.6e-06 28.2 0.5 2.9e-06 27.4 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 PSC74503.1 - 1e-05 25.8 1.4 1.6e-05 25.1 1.4 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type SURF2 PF05477.11 PSC74503.1 - 0.0023 17.6 1.7 0.0023 17.6 1.7 2.1 1 1 0 2 2 2 1 Surfeit locus protein 2 (SURF2) SNRNP27 PF08648.12 PSC74503.1 - 0.0043 17.1 1.1 0.0043 17.1 1.1 2.1 2 0 0 2 2 2 1 U4/U6.U5 small nuclear ribonucleoproteins zf-U1 PF06220.12 PSC74503.1 - 0.018 14.8 0.7 0.031 14.1 0.7 1.4 1 0 0 1 1 1 0 U1 zinc finger PBP1_TM PF14812.6 PSC74503.1 - 7.4 7.0 12.0 9.1 6.7 0.5 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mur_ligase_M PF08245.12 PSC74504.1 - 4e-14 53.0 1.5 4.3e-13 49.7 1.5 2.5 1 1 0 1 1 1 1 Mur ligase middle domain Mur_ligase_C PF02875.21 PSC74504.1 - 0.00028 21.1 0.0 0.00093 19.4 0.0 1.9 1 0 0 1 1 1 1 Mur ligase family, glutamate ligase domain PCI PF01399.27 PSC74505.1 - 4e-13 49.8 0.4 1.5e-12 48.0 0.3 2.0 2 0 0 2 2 2 1 PCI domain TPR_9 PF13371.6 PSC74505.1 - 0.05 13.8 1.8 0.88 9.8 0.3 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat rve PF00665.26 PSC74507.1 - 8.3e-19 67.9 0.0 1.8e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC74507.1 - 0.0066 16.2 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF262 PF03235.14 PSC74508.1 - 4.4e-19 69.6 0.0 4.3e-17 63.0 0.0 2.2 1 1 0 1 1 1 1 Protein of unknown function DUF262 rve PF00665.26 PSC74508.1 - 6.6e-19 68.3 0.0 1.6e-18 67.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC74508.1 - 0.0052 16.5 0.1 0.019 14.7 0.1 1.9 2 0 0 2 2 2 1 Integrase core domain NLE PF08154.12 PSC74508.1 - 0.065 13.8 0.3 0.17 12.4 0.3 1.6 1 0 0 1 1 1 0 NLE (NUC135) domain PrmA PF06325.13 PSC74509.1 - 1.4e-71 241.3 0.0 1.9e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 PSC74509.1 - 0.00065 19.5 0.3 0.0013 18.6 0.3 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PSC74509.1 - 0.0014 18.2 0.2 0.0023 17.5 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 PSC74509.1 - 0.0055 17.4 0.2 0.013 16.2 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 PSC74509.1 - 0.01 15.5 0.1 0.018 14.7 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Met_10 PF02475.16 PSC74509.1 - 0.071 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_23 PF13489.6 PSC74509.1 - 0.12 12.2 0.0 0.29 10.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 PSC74510.1 - 1.4e-71 241.3 0.0 1.9e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 PSC74510.1 - 0.00065 19.5 0.3 0.0013 18.6 0.3 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PSC74510.1 - 0.0014 18.2 0.2 0.0023 17.5 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 PSC74510.1 - 0.0055 17.4 0.2 0.013 16.2 0.2 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 PSC74510.1 - 0.01 15.5 0.1 0.018 14.7 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Met_10 PF02475.16 PSC74510.1 - 0.071 12.8 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_23 PF13489.6 PSC74510.1 - 0.12 12.2 0.0 0.29 10.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain RRM_1 PF00076.22 PSC74511.1 - 1.2e-44 150.0 0.0 3.9e-16 58.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PSC74511.1 - 1.5e-06 28.2 0.0 0.057 13.5 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 PSC74511.1 - 0.0018 18.3 0.0 0.004 17.2 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.6 PSC74511.1 - 0.0043 16.7 0.0 0.12 11.9 0.0 2.8 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 PSC74512.1 - 1.3e-44 149.9 0.0 4e-16 58.6 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PSC74512.1 - 1.6e-06 28.2 0.0 0.058 13.5 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 PSC74512.1 - 0.0018 18.3 0.0 0.0041 17.2 0.0 1.6 1 0 0 1 1 1 1 RNA binding motif RRM_5 PF13893.6 PSC74512.1 - 0.0044 16.6 0.0 0.13 11.9 0.0 2.8 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SET PF00856.28 PSC74513.1 - 5.9e-07 30.0 0.0 1.5e-06 28.7 0.0 1.6 1 1 0 1 1 1 1 SET domain Rubis-subs-bind PF09273.11 PSC74513.1 - 8.1e-07 29.8 0.1 1.3e-06 29.2 0.1 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Fe_bilin_red PF05996.12 PSC74514.1 - 5.3e-46 157.1 0.0 7.5e-46 156.6 0.0 1.2 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase NINJA_B PF16136.5 PSC74515.1 - 0.073 13.4 0.6 0.36 11.2 0.3 1.9 1 1 1 2 2 2 0 Putative nuclear localisation signal Kinesin PF00225.23 PSC74516.1 - 9.3e-103 343.6 0.0 1.5e-102 342.9 0.0 1.4 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PSC74516.1 - 6.5e-24 84.6 0.0 1.3e-23 83.6 0.0 1.5 1 0 0 1 1 1 1 Microtubule binding Tup_N PF08581.10 PSC74516.1 - 0.13 12.6 20.0 0.37 11.1 0.7 4.4 4 0 0 4 4 4 0 Tup N-terminal AAA_22 PF13401.6 PSC74516.1 - 0.19 12.0 2.8 3.9 7.7 0.0 3.5 3 0 0 3 3 3 0 AAA domain NPV_P10 PF05531.12 PSC74516.1 - 2 9.0 6.9 11 6.5 0.4 4.0 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein DUF3496 PF12001.8 PSC74516.1 - 3.1 8.2 10.0 1.1 9.7 6.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3496) Pirin PF02678.16 PSC74518.1 - 7.1e-33 112.8 0.5 1.4e-32 111.8 0.1 1.7 2 0 0 2 2 2 1 Pirin Pirin_C PF05726.13 PSC74518.1 - 1.9e-31 108.5 0.0 3.9e-31 107.5 0.0 1.5 1 0 0 1 1 1 1 Pirin C-terminal cupin domain adh_short PF00106.25 PSC74519.1 - 1.2e-31 109.7 1.6 1.4e-31 109.5 0.0 1.9 2 0 0 2 2 1 1 short chain dehydrogenase Myb_DNA-binding PF00249.31 PSC74519.1 - 7.4e-27 93.3 5.6 8e-13 48.4 0.4 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC74519.1 - 7e-21 74.2 1.4 1.4e-09 38.0 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain adh_short_C2 PF13561.6 PSC74519.1 - 3.1e-19 69.5 0.0 1.1e-18 67.6 0.0 1.9 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_deac_1 PF01522.21 PSC74519.1 - 2.8e-08 33.7 2.3 1.4e-07 31.5 0.0 3.1 4 0 0 4 4 4 1 Polysaccharide deacetylase KR PF08659.10 PSC74519.1 - 3.4e-06 27.1 0.0 0.0048 16.8 0.0 2.9 2 0 0 2 2 2 2 KR domain GDP_Man_Dehyd PF16363.5 PSC74519.1 - 0.00028 20.4 0.0 0.0015 18.0 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Myb_DNA-bind_7 PF15963.5 PSC74519.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Myb DNA-binding like Rap1_C PF11626.8 PSC74519.1 - 0.012 15.7 3.2 0.24 11.5 0.1 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Baculo_8kDa PF06096.11 PSC74519.1 - 0.026 14.6 0.2 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 Baculoviridae 8.2 KDa protein Epimerase PF01370.21 PSC74519.1 - 0.096 12.1 0.0 0.39 10.2 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family adh_short PF00106.25 PSC74520.1 - 2.4e-28 98.9 2.6 4.8e-26 91.4 0.0 2.9 2 1 0 2 2 2 1 short chain dehydrogenase Myb_DNA-binding PF00249.31 PSC74520.1 - 7.5e-27 93.3 5.6 8e-13 48.4 0.4 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC74520.1 - 7.1e-21 74.2 1.4 1.4e-09 38.0 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain adh_short_C2 PF13561.6 PSC74520.1 - 2.2e-16 60.1 0.0 1e-12 48.1 0.0 2.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_deac_1 PF01522.21 PSC74520.1 - 2.9e-08 33.7 2.3 1.4e-07 31.4 0.0 3.1 4 0 0 4 4 4 1 Polysaccharide deacetylase KR PF08659.10 PSC74520.1 - 2e-05 24.6 0.3 0.025 14.5 0.0 2.9 2 0 0 2 2 2 2 KR domain GDP_Man_Dehyd PF16363.5 PSC74520.1 - 0.0014 18.1 0.0 0.0079 15.6 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Myb_DNA-bind_7 PF15963.5 PSC74520.1 - 0.0097 15.8 0.0 0.025 14.5 0.0 1.6 1 0 0 1 1 1 1 Myb DNA-binding like Rap1_C PF11626.8 PSC74520.1 - 0.012 15.7 3.2 0.24 11.5 0.1 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Baculo_8kDa PF06096.11 PSC74520.1 - 0.026 14.6 0.2 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 Baculoviridae 8.2 KDa protein adh_short PF00106.25 PSC74521.1 - 1.2e-31 109.7 1.6 1.4e-31 109.5 0.0 1.9 2 0 0 2 2 1 1 short chain dehydrogenase Myb_DNA-binding PF00249.31 PSC74521.1 - 7.4e-27 93.3 5.6 8e-13 48.4 0.4 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC74521.1 - 7e-21 74.2 1.4 1.4e-09 38.0 0.2 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain adh_short_C2 PF13561.6 PSC74521.1 - 3.2e-19 69.4 0.0 1.1e-18 67.6 0.0 1.9 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_deac_1 PF01522.21 PSC74521.1 - 2.8e-08 33.7 2.3 1.4e-07 31.5 0.0 3.1 4 0 0 4 4 4 1 Polysaccharide deacetylase KR PF08659.10 PSC74521.1 - 3.4e-06 27.1 0.0 0.0048 16.8 0.0 2.9 2 0 0 2 2 2 2 KR domain GDP_Man_Dehyd PF16363.5 PSC74521.1 - 0.00028 20.4 0.0 0.0015 18.0 0.0 2.0 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Myb_DNA-bind_7 PF15963.5 PSC74521.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Myb DNA-binding like Rap1_C PF11626.8 PSC74521.1 - 0.012 15.7 3.2 0.24 11.5 0.1 2.5 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Baculo_8kDa PF06096.11 PSC74521.1 - 0.026 14.6 0.2 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 Baculoviridae 8.2 KDa protein Epimerase PF01370.21 PSC74521.1 - 0.096 12.1 0.0 0.39 10.2 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family CENP-T_C PF15511.6 PSC74522.1 - 8.4e-09 35.5 0.0 1e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TAF PF02969.17 PSC74522.1 - 8.7e-05 22.6 0.0 0.00013 22.0 0.0 1.4 1 1 0 1 1 1 1 TATA box binding protein associated factor (TAF) CENP-S PF15630.6 PSC74522.1 - 0.00014 22.2 0.1 0.00019 21.7 0.1 1.3 1 1 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 PSC74522.1 - 0.00074 19.8 0.1 0.0012 19.1 0.0 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 PSC74522.1 - 0.0013 19.1 0.2 0.0015 18.9 0.2 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.13 PSC74522.1 - 0.0019 18.2 0.1 0.0029 17.6 0.1 1.3 1 0 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 PSC74522.1 - 0.0096 16.0 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit HIGH_NTase1_ass PF16581.5 PSC74522.1 - 0.088 12.8 0.0 0.096 12.7 0.0 1.1 1 0 0 1 1 1 0 Cytidyltransferase-related C-terminal region Op_neuropeptide PF08035.11 PSC74523.1 - 0.081 12.8 0.3 0.18 11.7 0.3 1.6 1 0 0 1 1 1 0 Opioids neuropeptide HEAT PF02985.22 PSC74524.1 - 6.2e-20 69.6 18.1 0.0004 20.4 0.0 11.0 10 0 0 10 10 10 5 HEAT repeat Importin_rep_4 PF18808.1 PSC74524.1 - 6.6e-19 68.0 1.3 2.1e-14 53.6 0.0 4.6 4 0 0 4 4 4 2 Importin repeat HEAT_2 PF13646.6 PSC74524.1 - 1.9e-11 44.2 25.0 1.6e-06 28.4 0.5 9.7 6 3 4 10 10 10 2 HEAT repeats HEAT_EZ PF13513.6 PSC74524.1 - 2.3e-10 40.7 39.1 0.00068 20.1 0.0 12.5 11 4 5 16 16 15 4 HEAT-like repeat Vac14_Fab1_bd PF12755.7 PSC74524.1 - 7.4e-06 26.5 0.0 0.84 10.3 0.0 5.6 4 1 3 7 7 7 2 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 PSC74524.1 - 5.6e-05 22.8 1.0 20 4.7 0.1 5.6 5 1 1 6 6 6 0 CLASP N terminal Importin_rep_6 PF18829.1 PSC74524.1 - 0.00048 20.2 0.2 0.03 14.5 0.0 4.0 5 0 0 5 5 5 1 Importin repeat 6 DUF3385 PF11865.8 PSC74524.1 - 0.0011 18.9 0.0 6 6.8 0.0 4.8 5 1 1 6 6 6 1 Domain of unknown function (DUF3385) DUF4042 PF13251.6 PSC74524.1 - 0.0017 18.1 0.0 3 7.5 0.0 3.8 2 1 1 3 3 3 2 Domain of unknown function (DUF4042) DNA_alkylation PF08713.11 PSC74524.1 - 0.0017 18.1 0.0 2.1 8.0 0.0 2.6 2 0 0 2 2 2 2 DNA alkylation repair enzyme IBN_N PF03810.19 PSC74524.1 - 0.0072 16.2 0.0 4.4 7.3 0.0 3.8 3 0 0 3 3 3 1 Importin-beta N-terminal domain RIX1 PF08167.12 PSC74524.1 - 0.01 15.6 0.0 11 5.7 0.0 4.0 4 1 1 5 5 5 0 rRNA processing/ribosome biogenesis Arm PF00514.23 PSC74524.1 - 0.012 15.6 2.1 1.6 8.9 0.0 4.9 4 1 0 4 4 3 0 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 PSC74524.1 - 0.018 14.2 0.2 26 3.8 0.0 3.9 3 1 0 4 4 4 0 RNAPII transcription regulator C-terminal Nipped-B_C PF12830.7 PSC74524.1 - 0.064 13.2 0.3 7.2 6.5 0.1 3.0 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus TFIIE-A_C PF11521.8 PSC74524.1 - 0.17 12.2 0.1 0.17 12.2 0.1 2.4 2 0 0 2 2 1 0 C-terminal general transcription factor TFIIE alpha DRIM PF07539.12 PSC74524.1 - 0.2 9.9 0.7 26 3.0 0.0 3.8 4 1 0 4 4 4 0 Down-regulated in metastasis Cnd3 PF12719.7 PSC74524.1 - 0.71 9.0 3.3 63 2.6 0.0 4.3 4 1 0 4 4 4 0 Nuclear condensing complex subunits, C-term domain EF-hand_1 PF00036.32 PSC74525.1 - 1.5e-34 114.9 20.7 1.3e-09 36.9 1.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 PSC74525.1 - 6.9e-30 103.3 12.0 6.9e-17 61.7 0.9 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PSC74525.1 - 1e-26 90.5 13.4 1.5e-09 37.0 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 PSC74525.1 - 1.2e-25 89.1 12.2 2.9e-12 46.2 1.1 3.7 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 PSC74525.1 - 4e-16 57.7 22.3 5.2e-06 25.7 0.2 4.8 4 1 1 5 5 5 4 EF hand EF-hand_9 PF14658.6 PSC74525.1 - 1e-15 57.8 0.5 8.7e-07 29.2 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 PSC74525.1 - 1.7e-06 27.9 8.8 0.16 12.0 0.7 3.3 1 1 2 3 3 3 3 Cytoskeletal-regulatory complex EF hand SurA_N_2 PF13623.6 PSC74525.1 - 9.6e-05 22.3 2.4 0.17 11.7 0.1 2.7 1 1 1 2 2 2 2 SurA N-terminal domain SurA_N_3 PF13624.6 PSC74525.1 - 0.0001 22.1 2.5 0.029 14.2 0.3 2.1 1 1 1 2 2 2 2 SurA N-terminal domain SPARC_Ca_bdg PF10591.9 PSC74525.1 - 0.0003 21.1 0.1 0.17 12.2 0.0 2.1 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_14 PF17959.1 PSC74525.1 - 0.00072 19.8 1.6 0.24 11.8 0.2 2.4 2 0 0 2 2 2 2 EF-hand domain Dockerin_1 PF00404.18 PSC74525.1 - 0.00089 19.4 0.6 1.1 9.5 0.0 2.4 2 0 0 2 2 2 2 Dockerin type I domain SUB1_ProdP9 PF18213.1 PSC74525.1 - 0.015 15.1 1.2 0.035 13.9 0.2 1.9 2 0 0 2 2 2 0 SUB1 protease Prodomain ProdP9 UPF0154 PF03672.13 PSC74525.1 - 0.019 15.0 0.8 4 7.5 0.0 3.1 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) Sigma54_CBD PF04963.13 PSC74525.1 - 0.019 14.8 0.2 0.026 14.4 0.2 1.2 1 0 0 1 1 1 0 Sigma-54 factor, core binding domain PMBR PF09373.10 PSC74525.1 - 0.05 13.8 0.3 52 4.2 0.0 4.0 4 0 0 4 4 4 0 Pseudomurein-binding repeat Caleosin PF05042.13 PSC74525.1 - 0.052 13.5 1.2 8.3 6.3 0.0 3.5 1 1 3 4 4 4 0 Caleosin related protein DUF853 PF05872.12 PSC74525.1 - 0.056 12.0 0.3 1.7 7.1 0.0 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF853) Glyco_transf_92 PF01697.27 PSC74525.1 - 0.17 11.5 0.2 0.25 11.0 0.2 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 92 LETM1 PF07766.13 PSC74525.1 - 0.17 11.2 0.9 0.4 10.0 0.3 1.9 1 1 0 1 1 1 0 LETM1-like protein Gp-FAR-1 PF05823.12 PSC74525.1 - 0.32 11.3 4.3 1.6 9.1 0.2 2.9 2 1 2 4 4 4 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) SRI PF08236.11 PSC74525.1 - 0.4 10.9 2.4 0.92 9.7 0.1 2.6 3 0 0 3 3 3 0 SRI (Set2 Rpb1 interacting) domain Pectate_lyase_3 PF12708.7 PSC74526.1 - 2.8e-18 66.6 0.3 1.6e-17 64.1 0.1 2.0 2 0 0 2 2 2 1 Pectate lyase superfamily protein PAN_1 PF00024.26 PSC74526.1 - 6.5e-13 48.5 0.4 2.3e-05 24.3 0.0 2.3 2 0 0 2 2 2 2 PAN domain PAN_4 PF14295.6 PSC74526.1 - 6.8e-13 48.3 2.7 4.4e-06 26.5 0.2 2.6 2 0 0 2 2 2 2 PAN domain PAN_2 PF08276.11 PSC74526.1 - 0.0011 19.0 5.6 0.023 14.8 0.2 2.4 2 0 0 2 2 2 2 PAN-like domain Cupin_4 PF08007.12 PSC74527.1 - 2.2e-46 158.8 0.0 4.3e-46 157.9 0.0 1.4 1 1 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 PSC74527.1 - 0.0023 17.7 0.0 0.0041 16.9 0.0 1.3 1 0 0 1 1 1 1 Cupin-like domain FANCA_interact PF15751.5 PSC74527.1 - 0.0047 17.4 0.3 0.023 15.2 0.1 2.3 2 0 0 2 2 2 1 FAAP20 FANCA interaction domain NOC3p PF07540.11 PSC74530.1 - 8.2e-26 90.3 0.2 8.2e-26 90.3 0.2 2.5 3 0 0 3 3 3 1 Nucleolar complex-associated protein cwf18 PF08315.12 PSC74530.1 - 7.4e-19 68.8 0.4 7.4e-19 68.8 0.4 2.8 3 0 0 3 3 3 1 cwf18 pre-mRNA splicing factor CBF PF03914.17 PSC74530.1 - 5.7e-17 62.3 0.3 2.9e-16 60.0 0.0 2.5 2 1 0 2 2 2 1 CBF/Mak21 family Cnd1 PF12717.7 PSC74530.1 - 0.0059 16.7 0.4 4.2 7.4 0.1 2.4 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PSC74530.1 - 0.063 13.6 2.3 5.3 7.6 0.3 3.6 2 0 0 2 2 2 0 HEAT repeat Vac14_Fab1_bd PF12755.7 PSC74530.1 - 0.14 12.8 0.1 4.3 8.0 0.0 2.8 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 PSC74530.1 - 0.41 9.1 3.8 0.42 9.1 2.3 1.8 2 1 0 2 2 2 0 Adaptin N terminal region DUF4810 PF16068.5 PSC74530.1 - 1.1 9.9 4.6 3.3 8.3 4.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4810) Arm PF00514.23 PSC74530.1 - 1.2 9.3 3.6 13 6.0 0.3 2.9 2 0 0 2 2 2 0 Armadillo/beta-catenin-like repeat Folliculin PF11704.8 PSC74530.1 - 5.2 6.9 6.1 13 5.6 6.1 1.6 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport SET PF00856.28 PSC74531.1 - 1e-05 26.0 0.0 1.7e-05 25.3 0.0 1.4 1 1 0 1 1 1 1 SET domain adh_short PF00106.25 PSC74533.1 - 7.1e-19 68.0 0.0 6.5e-17 61.6 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PSC74533.1 - 9.1e-11 41.8 0.0 1.5e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC74533.1 - 3.3e-08 33.6 0.0 6.4e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 KR domain VWA PF00092.28 PSC74536.1 - 8.8e-10 39.1 0.0 6.1e-09 36.4 0.0 2.0 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 PSC74536.1 - 1.1e-07 32.5 0.0 2.7e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 PSC74536.1 - 0.017 14.5 0.0 0.081 12.3 0.0 1.9 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein OmpH PF03938.14 PSC74538.1 - 0.091 13.1 8.1 0.14 12.5 8.1 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) DUF4061 PF13270.6 PSC74538.1 - 6.3 7.2 6.4 1.8 8.9 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4061) NTP_transf_9 PF04248.12 PSC74539.1 - 5.6e-34 115.9 0.1 1e-33 115.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Cystatin PF00031.21 PSC74539.1 - 1.2e-08 35.1 0.1 1e-05 25.7 0.0 2.4 2 0 0 2 2 2 2 Cystatin domain SQAPI PF16845.5 PSC74539.1 - 1.2e-07 32.0 0.2 3.7e-06 27.2 0.1 2.4 2 0 0 2 2 2 1 Aspartic acid proteinase inhibitor NTP_transf_9 PF04248.12 PSC74540.1 - 4.4e-34 116.2 0.1 8.3e-34 115.3 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF427) Cystatin PF00031.21 PSC74540.1 - 1.7e-09 37.8 0.0 8.5e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Cystatin domain SQAPI PF16845.5 PSC74540.1 - 4.7e-08 33.3 0.3 3.1e-06 27.4 0.1 2.3 2 0 0 2 2 2 1 Aspartic acid proteinase inhibitor Isochorismatase PF00857.20 PSC74541.1 - 6.6e-86 286.9 0.0 2.5e-45 154.8 0.0 2.5 2 0 0 2 2 2 2 Isochorismatase family rve PF00665.26 PSC74541.1 - 1.9e-18 66.8 0.0 5.3e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC74541.1 - 0.014 15.2 0.3 0.047 13.5 0.0 2.0 2 0 0 2 2 2 0 Integrase core domain DUF4509 PF14970.6 PSC74541.1 - 0.23 11.4 3.0 0.42 10.5 3.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) Paralemmin PF03285.15 PSC74541.1 - 0.59 9.7 1.7 0.8 9.2 0.4 1.9 2 0 0 2 2 2 0 Paralemmin SAC3_GANP PF03399.16 PSC74542.1 - 4.7e-79 265.8 0.0 9.4e-79 264.8 0.0 1.5 1 0 0 1 1 1 1 SAC3/GANP family CSN8_PSD8_EIF3K PF10075.9 PSC74542.1 - 0.0076 16.2 0.0 0.016 15.2 0.0 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family Nucleoporin_FG PF13634.6 PSC74542.1 - 0.032 15.1 90.4 0.032 15.1 28.1 4.6 1 1 3 4 4 4 0 Nucleoporin FG repeat region CDC27 PF09507.10 PSC74542.1 - 6.5 6.0 25.8 23 4.2 25.8 2.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Ribosomal_L35p PF01632.19 PSC74543.1 - 1.1e-17 64.3 10.6 1.5e-17 63.9 10.6 1.2 1 0 0 1 1 1 1 Ribosomal protein L35 adh_short_C2 PF13561.6 PSC74544.1 - 1e-50 172.5 0.2 1.2e-50 172.3 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PSC74544.1 - 9.2e-35 119.9 0.1 1.1e-34 119.6 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC74545.1 - 9.1e-51 172.7 0.2 1.1e-50 172.5 0.2 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PSC74545.1 - 8.2e-35 120.0 0.1 1e-34 119.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase Ysc84 PF04366.12 PSC74547.1 - 3e-26 91.7 0.5 8.7e-26 90.2 0.1 2.0 2 0 0 2 2 2 1 Las17-binding protein actin regulator Senescence_reg PF04520.13 PSC74547.1 - 9.6e-05 23.3 1.1 9.6e-05 23.3 1.1 2.5 2 1 0 2 2 2 1 Senescence regulator HalX PF08663.10 PSC74547.1 - 0.15 12.4 1.8 0.3 11.4 0.3 2.3 3 0 0 3 3 3 0 HalX domain UPF0688 PF15772.5 PSC74547.1 - 1.2 9.3 7.8 0.097 12.9 1.1 2.0 1 1 1 2 2 2 0 UPF0688 family AF-4 PF05110.13 PSC74547.1 - 2.2 6.3 5.8 3 5.8 5.8 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein ketoacyl-synt PF00109.26 PSC74551.1 - 1.6e-85 286.7 14.3 1.7e-47 162.1 2.1 3.0 3 0 0 3 3 3 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 PSC74551.1 - 2.4e-54 182.4 13.0 2.1e-28 98.7 0.3 4.0 3 1 1 4 4 4 2 Beta-ketoacyl synthase, C-terminal domain PP-binding PF00550.25 PSC74551.1 - 1.4e-11 44.6 0.1 3.5e-11 43.3 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 PSC74551.1 - 0.0066 16.9 0.0 0.019 15.4 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension GBP_PSP PF02425.15 PSC74551.1 - 0.46 10.2 3.7 17 5.1 0.1 3.1 2 0 0 2 2 2 0 Paralytic/GBP/PSP peptide LpxC PF03331.13 PSC74552.1 - 1e-52 179.3 0.0 3.7e-42 144.7 0.0 2.2 2 0 0 2 2 2 2 UDP-3-O-acyl N-acetylglycosamine deacetylase rve PF00665.26 PSC74552.1 - 1.1e-18 67.6 0.0 2.2e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC74552.1 - 0.0091 15.8 0.0 0.022 14.5 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chloroa_b-bind PF00504.21 PSC74553.1 - 1.7e-51 174.9 0.1 2.1e-51 174.7 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Tropomyosin PF00261.20 PSC74554.1 - 0.0027 17.1 1.8 0.029 13.7 1.8 1.9 1 1 0 1 1 1 1 Tropomyosin DUF2514 PF10721.9 PSC74554.1 - 0.086 12.9 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Retrotran_gag_2 PF14223.6 PSC74555.1 - 1.9e-24 85.9 0.0 2.9e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 PSC74555.1 - 6.5e-23 81.2 0.0 1.4e-22 80.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain gag_pre-integrs PF13976.6 PSC74555.1 - 8.6e-09 35.1 0.0 1.7e-08 34.2 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain DUF4219 PF13961.6 PSC74555.1 - 3.1e-05 23.5 0.0 6.2e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) rve_3 PF13683.6 PSC74555.1 - 0.0014 18.3 0.0 0.0045 16.7 0.0 1.8 2 0 0 2 2 2 1 Integrase core domain RVT_2 PF07727.14 PSC74555.1 - 0.01 15.5 0.1 0.015 14.9 0.1 1.2 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) zf-CCHC_3 PF13917.6 PSC74555.1 - 0.1 12.6 0.3 0.27 11.2 0.3 1.7 1 0 0 1 1 1 0 Zinc knuckle zf-C2H2_10 PF16588.5 PSC74555.1 - 0.1 12.3 2.0 0.2 11.4 2.0 1.4 1 0 0 1 1 1 0 C2H2 zinc-finger Retrotran_gag_3 PF14244.6 PSC74555.1 - 0.14 12.0 0.0 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type Asp_protease_2 PF13650.6 PSC74555.1 - 0.18 12.5 0.0 0.45 11.2 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease zf-CCHC_5 PF14787.6 PSC74555.1 - 0.28 10.9 2.5 0.64 9.8 2.5 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger Dymeclin PF09742.9 PSC74556.1 - 3e-123 412.5 0.0 3.6e-123 412.2 0.0 1.0 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 PSC74556.1 - 7.7e-11 40.9 3.9 5.4e-06 24.9 1.7 2.2 2 0 0 2 2 2 2 High-temperature-induced dauer-formation protein AMP-binding PF00501.28 PSC74557.1 - 9.1e-80 268.3 0.0 1.2e-79 267.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme FlgN PF05130.12 PSC74557.1 - 0.1 13.1 2.6 0.34 11.4 2.6 1.9 1 0 0 1 1 1 0 FlgN protein NeA_P2 PF12312.8 PSC74557.1 - 0.18 11.3 0.1 0.51 9.7 0.1 1.7 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein DEAD PF00270.29 PSC74558.1 - 7e-42 143.2 0.0 1.5e-41 142.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC74558.1 - 5.1e-22 78.3 0.1 1.7e-21 76.6 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 PSC74558.1 - 3e-19 69.0 0.1 7e-19 67.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) eIF-3_zeta PF05091.12 PSC74558.1 - 0.021 13.8 2.3 0.026 13.5 2.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AAA_22 PF13401.6 PSC74558.1 - 0.046 14.0 1.1 2.5 8.4 0.3 3.1 2 1 1 3 3 3 0 AAA domain DUF4140 PF13600.6 PSC74558.1 - 0.17 12.3 4.6 0.56 10.7 4.0 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF1682 PF07946.14 PSC74558.1 - 3.5 6.7 14.5 6.1 6.0 14.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DEAD PF00270.29 PSC74559.1 - 7.5e-42 143.1 0.0 1.5e-41 142.1 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC74559.1 - 4.8e-22 78.4 0.1 1.7e-21 76.7 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 PSC74559.1 - 3e-19 69.0 0.1 7e-19 67.8 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) eIF-3_zeta PF05091.12 PSC74559.1 - 0.029 13.3 1.9 0.036 13.0 1.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) AAA_22 PF13401.6 PSC74559.1 - 0.052 13.8 1.1 2.5 8.4 0.3 3.0 2 1 1 3 3 3 0 AAA domain DUF4140 PF13600.6 PSC74559.1 - 0.16 12.4 4.3 0.54 10.7 3.7 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DUF1682 PF07946.14 PSC74559.1 - 7.4 5.7 13.9 13 4.9 13.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Rhomboid PF01694.22 PSC74560.1 - 2.3e-20 73.1 7.0 2.3e-20 73.1 7.0 1.7 3 0 0 3 3 3 1 Rhomboid family 2OG-FeII_Oxy_2 PF13532.6 PSC74561.1 - 3.5e-31 108.9 0.0 4e-31 108.7 0.0 1.0 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2967 PF11179.8 PSC74561.1 - 6.6 4.7 6.6 8.4 4.3 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) mTERF PF02536.14 PSC74562.1 - 0.0024 16.9 0.0 0.0029 16.6 0.0 1.0 1 0 0 1 1 1 1 mTERF TPR_12 PF13424.6 PSC74563.1 - 4.4e-25 87.8 3.1 6.4e-14 52.0 0.2 3.7 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 PSC74563.1 - 9.7e-19 66.6 10.7 2.3e-08 33.7 0.1 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat UVR PF02151.19 PSC74563.1 - 1.2e-06 28.0 14.3 0.0046 16.6 6.7 2.9 2 0 0 2 2 2 2 UvrB/uvrC motif TPR_7 PF13176.6 PSC74563.1 - 0.00013 21.7 0.0 0.0019 18.1 0.0 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat HEAT PF02985.22 PSC74563.1 - 0.0024 18.0 6.3 1.1 9.7 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat TPR_1 PF00515.28 PSC74563.1 - 0.0055 16.5 3.2 0.011 15.5 0.2 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat CLASP_N PF12348.8 PSC74563.1 - 0.018 14.6 0.0 0.049 13.2 0.0 1.6 2 0 0 2 2 2 0 CLASP N terminal HEAT_EZ PF13513.6 PSC74563.1 - 0.037 14.6 20.3 0.16 12.5 0.2 5.1 3 2 2 5 5 4 0 HEAT-like repeat TPR_8 PF13181.6 PSC74563.1 - 0.052 13.8 0.2 12 6.4 0.1 3.4 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 PSC74563.1 - 0.084 13.0 1.5 6.2 7.2 0.2 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TFIIA PF03153.13 PSC74563.1 - 0.088 12.8 7.5 0.086 12.8 0.4 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TPR_9 PF13371.6 PSC74563.1 - 0.34 11.1 6.6 2.6 8.3 0.1 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat DSPc PF00782.20 PSC74564.1 - 3.7e-21 75.3 0.0 6e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PSC74564.1 - 0.022 14.3 0.0 0.033 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Gelsolin PF00626.22 PSC74564.1 - 0.046 13.6 0.0 0.086 12.8 0.0 1.4 1 0 0 1 1 1 0 Gelsolin repeat CDC45 PF02724.14 PSC74565.1 - 0.21 9.9 2.5 3.7 5.7 0.5 2.1 2 0 0 2 2 2 0 CDC45-like protein SBP PF03110.14 PSC74566.1 - 3e-19 69.1 8.4 3e-19 69.1 8.4 2.9 3 0 0 3 3 3 1 SBP domain zf-MYND PF01753.18 PSC74566.1 - 3.1e-09 36.8 9.8 3.1e-09 36.8 9.8 2.3 2 0 0 2 2 2 1 MYND finger SBP PF03110.14 PSC74567.1 - 3e-19 69.1 8.4 3e-19 69.1 8.4 2.9 3 0 0 3 3 3 1 SBP domain zf-MYND PF01753.18 PSC74567.1 - 3.1e-09 36.8 9.8 3.1e-09 36.8 9.8 2.3 2 0 0 2 2 2 1 MYND finger SBP PF03110.14 PSC74568.1 - 3e-19 69.1 8.4 3e-19 69.1 8.4 2.9 3 0 0 3 3 3 1 SBP domain zf-MYND PF01753.18 PSC74568.1 - 3.1e-09 36.8 9.8 3.1e-09 36.8 9.8 2.3 2 0 0 2 2 2 1 MYND finger DTW PF03942.15 PSC74569.1 - 6.2e-29 101.1 0.0 1.8e-28 99.6 0.0 1.8 1 1 0 1 1 1 1 DTW domain DUF2892 PF11127.8 PSC74569.1 - 8.9e-05 22.4 0.3 8.9e-05 22.4 0.3 3.1 3 0 0 3 3 2 1 Protein of unknown function (DUF2892) TFIIA PF03153.13 PSC74569.1 - 9.7e-05 22.5 27.0 9.7e-05 22.5 27.0 2.6 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit PIP5K PF01504.18 PSC74569.1 - 0.00012 21.4 0.6 0.00024 20.4 0.6 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Pkinase PF00069.25 PSC74569.1 - 0.0028 17.0 0.0 0.0066 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74569.1 - 0.0055 16.0 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase MID_MedPIWI PF18296.1 PSC74569.1 - 0.006 16.4 4.1 0.015 15.1 4.1 1.6 1 0 0 1 1 1 1 MID domain of medPIWI vWA-TerF-like PF10138.9 PSC74569.1 - 0.17 12.0 1.0 0.29 11.2 1.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus FTA2 PF13095.6 PSC74569.1 - 0.71 9.5 0.0 0.71 9.5 0.0 2.3 2 0 0 2 2 1 0 Kinetochore Sim4 complex subunit FTA2 Velvet PF11754.8 PSC74569.1 - 2.6 7.9 12.6 0.16 11.8 6.2 2.1 2 0 0 2 2 2 0 Velvet factor DDHD PF02862.17 PSC74569.1 - 3.7 7.7 11.9 0.79 9.8 4.9 2.4 2 0 0 2 2 2 0 DDHD domain Afi1 PF07792.12 PSC74569.1 - 5.1 7.6 10.8 14 6.1 10.8 1.7 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Neur_chan_memb PF02932.16 PSC74569.1 - 6.2 6.8 11.8 0.1 12.6 2.1 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region CLN3 PF02487.17 PSC74569.1 - 9.5 5.1 8.7 21 4.0 8.7 1.5 1 0 0 1 1 1 0 CLN3 protein AUX_IAA PF02309.16 PSC74569.1 - 9.9 5.9 11.1 0.24 11.2 0.3 2.4 2 0 0 2 2 2 0 AUX/IAA family DUF3783 PF12646.7 PSC74570.1 - 2.1e-05 24.4 0.0 4.3e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3783) SecY PF00344.20 PSC74571.1 - 4e-70 236.5 11.1 4.9e-70 236.2 11.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 PSC74571.1 - 8.6e-16 57.5 1.1 1.3e-15 56.9 0.0 1.9 2 0 0 2 2 2 1 Plug domain of Sec61p Methyltransf_17 PF12692.7 PSC74571.1 - 0.1 12.6 0.0 0.27 11.2 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl-L-methionine methyltransferase E1-E2_ATPase PF00122.20 PSC74572.1 - 1.8e-51 174.2 8.1 2.1e-50 170.8 0.2 3.7 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 PSC74572.1 - 3.7e-18 66.6 0.5 1.9e-17 64.2 0.5 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 PSC74572.1 - 4.3e-12 45.5 0.0 8e-12 44.7 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PSC74572.1 - 0.00044 20.1 0.5 0.0023 17.7 0.3 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PSC74572.1 - 0.0011 19.0 0.0 0.0026 17.8 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Amidohydro_2 PF04909.14 PSC74572.1 - 0.016 15.0 0.0 0.027 14.3 0.0 1.3 1 0 0 1 1 1 0 Amidohydrolase YscO PF07321.12 PSC74573.1 - 0.00021 21.2 16.4 0.00021 21.2 16.4 2.2 1 1 1 2 2 2 1 Type III secretion protein YscO Leu_zip PF15294.6 PSC74573.1 - 0.0057 16.2 4.3 0.0068 16.0 4.3 1.1 1 0 0 1 1 1 1 Leucine zipper GTP-bdg_M PF16360.5 PSC74573.1 - 0.01 16.4 5.4 0.077 13.6 5.4 2.3 1 1 0 1 1 1 0 GTP-binding GTPase Middle Region TPR_MLP1_2 PF07926.12 PSC74573.1 - 0.013 15.5 19.1 0.017 15.2 12.0 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Lebercilin PF15619.6 PSC74573.1 - 0.22 11.1 12.4 0.74 9.4 12.4 1.7 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease Filament PF00038.21 PSC74573.1 - 0.26 10.9 11.7 3.1 7.3 10.4 1.9 1 1 1 2 2 2 0 Intermediate filament protein Spc7 PF08317.11 PSC74573.1 - 0.81 8.5 12.2 0.87 8.4 4.9 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF724 PF05266.14 PSC74573.1 - 0.84 9.4 5.3 1.1 9.0 5.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Atg14 PF10186.9 PSC74573.1 - 1.1 8.3 9.1 1.6 7.8 9.1 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 KxDL PF10241.9 PSC74573.1 - 1.2 9.5 5.5 3.9 7.8 0.7 2.3 1 1 2 3 3 3 0 Uncharacterized conserved protein Fez1 PF06818.15 PSC74573.1 - 1.4 9.4 9.6 1.9 8.9 9.6 1.1 1 0 0 1 1 1 0 Fez1 ADIP PF11559.8 PSC74573.1 - 2.1 8.4 13.3 0.91 9.6 4.5 2.0 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Swi5 PF07061.11 PSC74573.1 - 2.8 8.1 7.7 4.7 7.4 0.4 2.8 3 0 0 3 3 3 0 Swi5 Adaptin_binding PF10199.9 PSC74573.1 - 4.5 7.9 6.9 5.6 7.6 6.9 1.1 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Spc24 PF08286.11 PSC74573.1 - 6.2 7.1 6.3 18 5.6 1.9 2.3 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF4472 PF14739.6 PSC74573.1 - 9.1 7.1 10.6 19 6.0 4.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) 5_nucleotid_C PF02872.18 PSC74575.1 - 3.6e-37 128.0 0.0 8.5e-37 126.8 0.0 1.7 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 PSC74575.1 - 4.6e-07 30.5 0.0 7e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase G-patch PF01585.23 PSC74576.1 - 6.6e-11 41.9 2.4 6.6e-11 41.9 2.4 2.5 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.7 PSC74576.1 - 0.014 15.4 2.6 0.014 15.4 2.6 2.8 2 0 0 2 2 2 0 G-patch domain R3H PF01424.22 PSC74576.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 R3H domain G-patch PF01585.23 PSC74577.1 - 6.6e-11 41.9 2.4 6.6e-11 41.9 2.4 2.4 3 0 0 3 3 3 1 G-patch domain G-patch_2 PF12656.7 PSC74577.1 - 0.014 15.4 2.6 0.014 15.4 2.6 2.8 2 0 0 2 2 2 0 G-patch domain R3H PF01424.22 PSC74577.1 - 0.12 12.4 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 R3H domain Ank_2 PF12796.7 PSC74578.1 - 3.2e-14 53.3 1.7 8e-06 26.4 0.4 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC74578.1 - 4.1e-09 36.5 7.1 0.00023 21.4 0.5 3.7 1 1 3 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC74578.1 - 2e-08 33.8 2.5 0.31 11.7 0.0 4.4 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 PSC74578.1 - 1.8e-07 31.6 6.3 0.00018 22.0 0.3 3.1 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 PSC74578.1 - 0.0021 18.4 8.1 9.7 6.8 0.4 4.1 3 1 0 3 3 3 3 Ankyrin repeat AF-4 PF05110.13 PSC74578.1 - 2.6 6.0 10.4 3.4 5.6 10.4 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein WD40 PF00400.32 PSC74579.1 - 2.4e-33 113.6 5.8 6.4e-06 26.8 0.0 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC74579.1 - 1.3e-11 44.6 0.2 0.024 14.9 0.0 5.4 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 PSC74579.1 - 9.8e-05 21.8 0.0 0.0002 20.8 0.0 1.4 1 0 0 1 1 1 1 WD40-like domain Ge1_WD40 PF16529.5 PSC74579.1 - 0.0043 16.0 0.0 5.3 5.9 0.0 3.6 2 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PSC74579.1 - 0.078 11.6 0.6 2.5 6.6 0.2 2.3 1 1 1 2 2 2 0 Nucleoporin Nup120/160 Suf PF05843.14 PSC74579.1 - 0.64 10.0 4.9 1 9.3 4.9 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 PSC74579.1 - 5.8 6.8 9.0 9.8 6.1 9.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SBP PF03110.14 PSC74580.1 - 3.2e-18 65.8 12.7 3.2e-18 65.8 12.7 2.9 3 0 0 3 3 3 1 SBP domain Peptidase_S64 PF08192.11 PSC74580.1 - 0.27 9.7 6.7 0.34 9.3 6.7 1.1 1 0 0 1 1 1 0 Peptidase family S64 Vfa1 PF08432.10 PSC74580.1 - 2.2 8.6 23.5 3.9 7.8 23.5 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF4407 PF14362.6 PSC74580.1 - 4.4 6.6 23.2 9.8 5.4 23.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Exonuc_VII_L PF02601.15 PSC74580.1 - 8.4 5.9 22.9 16 5.0 22.9 1.5 1 0 0 1 1 1 0 Exonuclease VII, large subunit Smr PF01713.21 PSC74581.1 - 7.9e-06 26.2 0.1 2.2e-05 24.7 0.1 1.8 1 0 0 1 1 1 1 Smr domain TRP PF06011.12 PSC74581.1 - 3.9e-05 22.6 11.6 5.6e-05 22.0 11.6 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF1771 PF08590.10 PSC74581.1 - 3.8 8.0 16.0 0.055 13.8 7.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) Smr PF01713.21 PSC74582.1 - 7.9e-06 26.1 0.1 2.2e-05 24.7 0.1 1.8 1 0 0 1 1 1 1 Smr domain TRP PF06011.12 PSC74582.1 - 3.9e-05 22.6 11.6 5.6e-05 22.0 11.6 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF1771 PF08590.10 PSC74582.1 - 3.8 8.0 16.0 0.055 13.8 7.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) Smr PF01713.21 PSC74583.1 - 7.9e-06 26.1 0.1 2.2e-05 24.7 0.1 1.8 1 0 0 1 1 1 1 Smr domain TRP PF06011.12 PSC74583.1 - 3.3e-05 22.8 11.3 4.8e-05 22.3 11.3 1.2 1 0 0 1 1 1 1 Transient receptor potential (TRP) ion channel DUF1771 PF08590.10 PSC74583.1 - 3.9 7.9 16.0 0.056 13.8 7.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1771) Herpes_capsid PF06112.11 PSC74584.1 - 2.2 8.3 6.9 3.3 7.7 6.9 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein ENTH PF01417.20 PSC74585.1 - 4.1e-30 104.4 0.0 6.6e-30 103.7 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 PSC74585.1 - 0.17 10.9 0.1 0.24 10.4 0.1 1.2 1 0 0 1 1 1 0 ANTH domain T7SS_ESX_EspC PF10824.8 PSC74585.1 - 0.18 12.3 2.3 0.86 10.1 2.3 2.2 1 0 0 1 1 1 0 Excreted virulence factor EspC, type VII ESX diderm TPR_2 PF07719.17 PSC74586.1 - 3.7e-12 45.4 9.1 0.0087 16.1 0.1 5.1 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.6 PSC74586.1 - 2.2e-10 41.0 23.7 6.3e-05 23.5 8.6 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 PSC74586.1 - 2.1e-09 36.8 5.3 0.0031 17.3 0.1 4.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_9 PF13371.6 PSC74586.1 - 1.2e-07 31.8 17.3 0.034 14.3 0.6 4.3 2 1 2 4 4 4 4 Tetratricopeptide repeat TPR_12 PF13424.6 PSC74586.1 - 5.7e-07 29.7 14.3 0.00022 21.4 1.0 3.9 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 PSC74586.1 - 4.9e-05 23.8 9.6 0.034 14.6 0.1 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 PSC74586.1 - 0.00032 20.5 5.9 0.48 10.6 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat SHNi-TPR PF10516.9 PSC74586.1 - 0.0012 18.3 1.0 0.23 10.9 0.2 2.8 3 0 0 3 3 3 1 SHNi-TPR TPR_15 PF13429.6 PSC74586.1 - 0.0062 15.8 0.4 3.7 6.7 0.0 2.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 PSC74586.1 - 0.011 15.4 1.7 2.9 7.6 0.2 3.7 2 1 2 4 4 4 0 TPR repeat TPR_10 PF13374.6 PSC74586.1 - 0.012 15.5 15.3 12 5.9 0.1 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_6 PF13174.6 PSC74586.1 - 0.026 15.2 5.4 50 4.8 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 PSC74586.1 - 0.07 14.0 22.6 0.3 12.0 1.1 5.1 2 2 3 5 5 5 0 Tetratricopeptide repeat TPR_4 PF07721.14 PSC74586.1 - 0.63 10.8 29.8 0.93 10.3 4.4 5.6 5 0 0 5 5 5 0 Tetratricopeptide repeat WD40 PF00400.32 PSC74587.1 - 1.5e-31 107.9 8.9 1.8e-06 28.6 0.0 8.1 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC74587.1 - 2.1e-18 66.4 0.1 2.8e-06 27.5 0.0 5.6 3 1 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PSC74587.1 - 0.00019 20.5 0.3 2.9 6.8 0.0 4.3 3 1 3 6 6 6 2 WD40 region of Ge1, enhancer of mRNA-decapping protein TPR_11 PF13414.6 PSC74587.1 - 0.00061 19.4 3.0 0.014 15.1 0.2 2.5 2 0 0 2 2 2 1 TPR repeat DUF3460 PF11943.8 PSC74587.1 - 0.2 11.9 0.2 0.49 10.7 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3460) Nbas_N PF15492.6 PSC74587.1 - 0.21 10.9 1.6 16 4.7 0.0 3.5 4 1 0 4 4 4 0 Neuroblastoma-amplified sequence, N terminal M16C_assoc PF08367.11 PSC74588.1 - 1.6e-55 188.0 0.0 2.5e-55 187.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 PSC74588.1 - 7e-09 36.0 0.0 5.3e-05 23.3 0.0 3.8 2 1 0 2 2 2 2 Peptidase M16 inactive domain PsbP PF01789.16 PSC74590.1 - 4.8e-14 52.8 0.0 5.9e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 PsbP KR PF08659.10 PSC74591.1 - 1.9e-06 27.9 0.3 2.8e-06 27.4 0.3 1.2 1 0 0 1 1 1 1 KR domain Lipocalin_2 PF08212.12 PSC74591.1 - 0.22 11.5 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipocalin-like domain ketoacyl-synt PF00109.26 PSC74592.1 - 1.1e-46 159.5 6.1 2.3e-46 158.4 6.1 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 PSC74592.1 - 8.8e-27 93.5 0.5 1.7e-26 92.6 0.5 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 PSC74592.1 - 8e-06 25.9 0.3 1.6e-05 24.9 0.3 1.5 1 0 0 1 1 1 1 KR domain Bromodomain PF00439.25 PSC74593.1 - 5.3e-18 64.9 0.0 1e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 PSC74593.1 - 1.9e-10 40.8 0.0 4.6e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Tim44 PF04280.15 PSC74593.1 - 7e-09 35.9 0.0 1.6e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 Tim44-like domain Bromodomain PF00439.25 PSC74594.1 - 5.3e-18 64.9 0.0 1e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 PSC74594.1 - 1.9e-10 40.8 0.0 4.5e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation Tim44 PF04280.15 PSC74594.1 - 7e-09 35.9 0.0 1.6e-06 28.3 0.0 2.4 2 0 0 2 2 2 2 Tim44-like domain DUF268 PF03269.14 PSC74595.1 - 3.2e-13 49.9 0.0 3.4e-13 49.8 0.0 1.0 1 0 0 1 1 1 1 Caenorhabditis protein of unknown function, DUF268 FAD_binding_4 PF01565.23 PSC74596.1 - 2.9e-27 95.1 4.7 1e-26 93.3 3.1 2.6 2 0 0 2 2 2 1 FAD binding domain rve PF00665.26 PSC74596.1 - 4.2e-18 65.7 0.0 8.8e-18 64.6 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain BBE PF08031.12 PSC74596.1 - 3.1e-08 33.6 0.0 5.5e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Berberine and berberine like fn3 PF00041.21 PSC74596.1 - 0.0014 18.9 0.0 0.0045 17.3 0.0 1.9 1 1 0 1 1 1 1 Fibronectin type III domain rve_3 PF13683.6 PSC74596.1 - 0.031 14.1 0.0 0.075 12.8 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain SRCR PF00530.18 PSC74597.1 - 3.7e-50 168.5 12.8 7.2e-13 48.9 0.0 7.3 6 2 1 7 7 7 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PSC74597.1 - 0.023 15.2 1.5 1.3 9.6 0.1 3.5 3 0 0 3 3 3 0 Scavenger receptor cysteine-rich domain SRCR PF00530.18 PSC74598.1 - 4.4e-46 155.5 10.4 6.6e-13 49.0 0.0 7.2 6 2 0 6 6 6 4 Scavenger receptor cysteine-rich domain SRCR_2 PF15494.6 PSC74598.1 - 0.011 16.2 0.8 1.2 9.7 0.1 3.5 3 0 0 3 3 3 0 Scavenger receptor cysteine-rich domain ParA PF10609.9 PSC74599.1 - 5.2e-90 301.2 0.0 8.4e-83 277.6 0.0 2.1 2 0 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 PSC74599.1 - 1.3e-14 54.3 0.0 6.6e-12 45.6 0.0 2.4 2 1 0 2 2 2 2 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 PSC74599.1 - 1.4e-08 34.9 0.0 2.7e-07 30.7 0.0 2.1 1 1 0 1 1 1 1 AAA domain MipZ PF09140.11 PSC74599.1 - 6e-07 29.0 0.0 2.7e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 PSC74599.1 - 6.8e-07 28.8 0.1 1.2e-05 24.7 0.0 2.4 2 1 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 PSC74599.1 - 0.0003 20.3 0.1 0.0027 17.2 0.1 2.0 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 PSC74599.1 - 0.0024 17.4 0.0 0.053 13.0 0.0 2.2 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 PSC74599.1 - 0.0029 17.5 0.4 0.94 9.3 0.0 2.6 2 1 0 2 2 2 1 AAA domain MeaB PF03308.16 PSC74599.1 - 0.0036 16.3 0.1 0.0064 15.5 0.1 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_25 PF13481.6 PSC74599.1 - 0.0053 16.4 0.1 0.013 15.1 0.1 1.6 1 0 0 1 1 1 1 AAA domain APS_kinase PF01583.20 PSC74599.1 - 0.0079 16.1 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Adenylylsulphate kinase RsgA_GTPase PF03193.16 PSC74599.1 - 0.017 15.0 0.0 0.22 11.4 0.0 2.1 2 0 0 2 2 2 0 RsgA GTPase CLP1_P PF16575.5 PSC74599.1 - 0.036 13.9 0.0 0.083 12.7 0.0 1.5 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NB-ARC PF00931.22 PSC74599.1 - 0.089 12.0 0.0 0.14 11.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain SRP54 PF00448.22 PSC74599.1 - 0.1 12.2 0.0 0.37 10.4 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TsaE PF02367.17 PSC74599.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 PSC74599.1 - 0.17 11.8 0.3 0.28 11.1 0.3 1.3 1 0 0 1 1 1 0 NACHT domain DUF382 PF04037.13 PSC74600.1 - 1.5e-57 193.2 0.8 1.5e-57 193.2 0.8 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF382) PSP PF04046.16 PSC74600.1 - 1.3e-21 76.2 3.8 2.7e-21 75.2 3.8 1.6 1 0 0 1 1 1 1 PSP Reprolysin_5 PF13688.6 PSC74601.1 - 1.4e-13 51.5 0.0 3.6e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_4 PF13583.6 PSC74601.1 - 9.2e-08 32.0 1.1 4.4e-07 29.7 1.1 2.1 1 1 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.6 PSC74601.1 - 1.5e-07 31.9 0.2 5.3e-07 30.2 0.0 2.1 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 PSC74601.1 - 0.0029 17.5 0.5 0.0076 16.2 0.5 1.6 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.8 PSC74601.1 - 0.073 11.7 0.1 0.11 11.0 0.1 1.2 1 0 0 1 1 1 0 Putative peptidase family Tmemb_14 PF03647.13 PSC74601.1 - 0.95 10.2 10.0 7.7 7.3 0.0 4.0 4 0 0 4 4 4 0 Transmembrane proteins 14C eIF-3c_N PF05470.12 PSC74602.1 - 1.8e-168 561.6 7.0 1.8e-168 561.6 7.0 1.9 1 1 1 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 PSC74602.1 - 1.6e-15 57.5 0.0 1.3e-14 54.6 0.0 2.7 3 0 0 3 3 3 1 PCI domain RAP1 PF07218.11 PSC74602.1 - 0.45 8.7 7.5 0.62 8.3 7.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Macoilin PF09726.9 PSC74602.1 - 0.5 8.9 15.6 0.77 8.2 15.6 1.2 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 PSC74602.1 - 0.88 9.1 18.6 2.4 7.7 18.6 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Secretin_N_2 PF07655.13 PSC74602.1 - 4.1 8.0 14.6 11 6.7 14.6 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain SOBP PF15279.6 PSC74602.1 - 5.3 7.5 13.4 2.4 8.7 10.3 1.9 1 1 1 2 2 2 0 Sine oculis-binding protein BSP_II PF05432.11 PSC74602.1 - 9 5.9 23.1 2.9 7.5 0.0 3.2 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) ADP_ribosyl_GH PF03747.14 PSC74603.1 - 3.4e-53 181.3 6.9 4.2e-53 181.0 6.9 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Pea-VEAacid PF08111.11 PSC74603.1 - 0.088 13.2 1.0 0.18 12.2 0.1 2.1 2 0 0 2 2 2 0 Pea-VEAacid family Metallophos PF00149.28 PSC74604.1 - 9.1e-15 55.7 0.0 1.1e-14 55.4 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PSC74604.1 - 0.054 13.7 0.0 0.074 13.2 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain GATA PF00320.27 PSC74606.1 - 4.3e-06 26.2 7.9 6.9e-06 25.6 7.9 1.3 1 0 0 1 1 1 1 GATA zinc finger T2SSF PF00482.23 PSC74606.1 - 3 7.8 10.8 1.8 8.5 1.7 3.0 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F EST1_DNA_bind PF10373.9 PSC74611.1 - 2.5e-26 92.8 0.0 3.5e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain EST1 PF10374.9 PSC74611.1 - 1.1e-17 65.0 0.0 2.4e-17 63.8 0.0 1.6 1 0 0 1 1 1 1 Telomerase activating protein Est1 Abhydrolase_1 PF00561.20 PSC74612.1 - 4.1e-19 69.2 0.2 3.9e-18 66.0 0.2 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PSC74612.1 - 7e-11 43.1 1.5 7e-11 43.1 1.5 4.4 2 1 2 4 4 4 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PSC74612.1 - 4.6e-09 35.9 0.7 4.6e-09 35.9 0.7 2.2 2 1 0 2 2 2 1 Serine aminopeptidase, S33 GATA PF00320.27 PSC74612.1 - 3.6e-08 32.9 6.8 1.7e-06 27.6 6.6 2.6 2 0 0 2 2 2 1 GATA zinc finger SUIM_assoc PF16619.5 PSC74612.1 - 0.18 11.9 15.8 0.065 13.3 0.7 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 PSC74612.1 - 0.19 11.7 17.1 1.8 8.4 8.2 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 PSC74612.1 - 1.2 8.7 13.0 4.8 6.7 7.6 2.1 2 0 0 2 2 2 0 Spt20 family Abhydrolase_1 PF00561.20 PSC74613.1 - 1.1e-21 77.7 0.5 9.7e-21 74.6 0.5 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PSC74613.1 - 5e-15 56.7 2.7 5e-15 56.7 2.7 4.4 2 1 1 4 4 4 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PSC74613.1 - 1e-09 38.0 0.2 1e-09 38.0 0.2 2.4 2 1 0 2 2 2 1 Serine aminopeptidase, S33 GATA PF00320.27 PSC74613.1 - 3.6e-08 32.9 6.8 1.7e-06 27.5 6.6 2.6 2 0 0 2 2 2 1 GATA zinc finger SUIM_assoc PF16619.5 PSC74613.1 - 0.18 11.9 15.8 0.066 13.3 0.7 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 PSC74613.1 - 0.2 11.6 17.1 1.9 8.4 8.2 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 PSC74613.1 - 1.2 8.7 13.0 4.9 6.7 7.6 2.1 2 0 0 2 2 2 0 Spt20 family Abhydrolase_1 PF00561.20 PSC74614.1 - 1.1e-21 77.7 0.5 9.7e-21 74.6 0.5 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PSC74614.1 - 5e-15 56.7 2.7 5e-15 56.7 2.7 4.4 2 1 1 4 4 4 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PSC74614.1 - 1e-09 38.0 0.2 1e-09 38.0 0.2 2.4 2 1 0 2 2 2 1 Serine aminopeptidase, S33 GATA PF00320.27 PSC74614.1 - 3.6e-08 32.9 6.8 1.7e-06 27.5 6.6 2.6 2 0 0 2 2 2 1 GATA zinc finger SUIM_assoc PF16619.5 PSC74614.1 - 0.18 11.9 15.8 0.066 13.3 0.7 3.4 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 PSC74614.1 - 0.2 11.6 17.1 1.9 8.4 8.2 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 PSC74614.1 - 1.2 8.7 13.0 4.9 6.7 7.6 2.1 2 0 0 2 2 2 0 Spt20 family Zip PF02535.22 PSC74615.1 - 2.4e-30 105.9 12.3 1.3e-29 103.5 12.4 1.8 1 1 0 1 1 1 1 ZIP Zinc transporter EF-hand_13 PF17958.1 PSC74615.1 - 1.9e-28 98.1 0.0 1.7e-27 95.1 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 PSC74615.1 - 9.5e-19 67.6 0.0 1.1e-16 61.0 0.0 3.4 3 1 0 3 3 3 1 EF-hand domain pair WW PF00397.26 PSC74615.1 - 9.5e-07 28.8 0.1 6.2e-06 26.2 0.1 2.3 2 0 0 2 2 2 1 WW domain EF-hand_1 PF00036.32 PSC74615.1 - 5.9e-06 25.5 0.8 0.0048 16.4 0.0 3.5 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 PSC74615.1 - 0.0002 21.0 1.6 0.012 15.4 0.0 3.5 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 PSC74615.1 - 0.00028 20.2 2.1 0.0014 18.1 0.0 2.8 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 PSC74615.1 - 0.92 9.4 3.4 4.7 7.1 0.2 3.3 4 0 0 4 4 4 0 EF-hand domain pair Mlo PF03094.15 PSC74617.1 - 3.5e-43 147.7 4.2 9.5e-17 60.5 0.0 3.5 3 1 0 3 3 3 3 Mlo family zf-C3HC4 PF00097.25 PSC74618.1 - 1.4e-08 34.5 2.1 5.7e-08 32.5 2.1 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 PSC74618.1 - 2.8e-08 33.8 7.0 2.8e-07 30.6 7.0 2.4 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING SPX PF03105.19 PSC74618.1 - 2.9e-08 34.1 0.0 0.00021 21.3 0.0 2.4 2 0 0 2 2 2 2 SPX domain zf-RING_UBOX PF13445.6 PSC74618.1 - 2.2e-07 30.8 4.5 5.4e-07 29.5 4.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PSC74618.1 - 2.6e-07 30.4 7.1 2.7e-07 30.3 3.1 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC74618.1 - 2.2e-06 27.9 4.4 2.2e-06 27.9 4.4 2.3 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 PSC74618.1 - 6.7e-05 22.7 8.5 0.0012 18.6 8.5 2.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC74618.1 - 0.0001 22.2 5.0 0.0001 22.2 5.0 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 PSC74618.1 - 0.021 14.7 0.9 0.021 14.7 0.9 2.6 3 0 0 3 3 3 0 zf-RING of BARD1-type protein zf-Nse PF11789.8 PSC74618.1 - 0.13 12.1 3.0 0.095 12.5 0.9 1.9 2 1 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_10 PF16685.5 PSC74618.1 - 0.16 12.2 8.3 2.5 8.3 4.9 3.1 2 1 0 2 2 2 0 zinc RING finger of MSL2 Zn_Tnp_IS1 PF03811.13 PSC74618.1 - 1.7 8.4 5.6 0.35 10.6 1.1 2.2 2 0 0 2 2 2 0 InsA N-terminal domain Nucleotid_trans PF03407.16 PSC74619.1 - 2.7e-49 168.0 0.0 4.5e-49 167.3 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Phospholip_B PF04916.13 PSC74620.1 - 1.3e-147 492.6 0.0 1.5e-147 492.4 0.0 1.0 1 0 0 1 1 1 1 Phospholipase B Phospholip_B PF04916.13 PSC74621.1 - 1.3e-147 492.6 0.0 1.6e-147 492.3 0.0 1.0 1 0 0 1 1 1 1 Phospholipase B Histone PF00125.24 PSC74622.1 - 4.2e-51 172.7 1.8 5.6e-51 172.3 1.8 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CAP PF00188.26 PSC74622.1 - 4.1e-17 63.2 0.8 6.6e-17 62.5 0.8 1.3 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PAF PF15715.5 PSC74622.1 - 0.002 18.7 2.8 0.0034 18.0 2.8 1.3 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-S PF15630.6 PSC74622.1 - 0.012 15.9 0.0 0.021 15.2 0.0 1.2 1 0 0 1 1 1 0 CENP-S protein CENP-T_C PF15511.6 PSC74622.1 - 0.02 15.0 0.0 0.033 14.3 0.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold CBFD_NFYB_HMF PF00808.23 PSC74622.1 - 0.21 11.9 0.0 0.32 11.3 0.0 1.3 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 PSC74622.1 - 0.25 11.4 0.0 0.4 10.8 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Hemerythrin PF01814.23 PSC74623.1 - 0.00062 20.4 5.3 0.0022 18.6 3.8 2.1 1 1 1 2 2 2 2 Hemerythrin HHE cation binding domain HARE-HTH PF05066.13 PSC74624.1 - 8.3e-12 45.3 0.0 1.8e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain MAPEG PF01124.18 PSC74624.1 - 0.12 12.2 1.7 0.71 9.8 1.7 2.3 1 0 0 1 1 1 0 MAPEG family SHOCT PF09851.9 PSC74624.1 - 3.8 7.4 8.5 7.3 6.5 0.5 3.3 3 0 0 3 3 3 0 Short C-terminal domain MFS_1 PF07690.16 PSC74625.1 - 1.5e-06 27.4 37.4 1.5e-06 27.4 37.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA PF00004.29 PSC74626.1 - 2.3e-41 141.3 0.0 4.9e-41 140.3 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 PSC74626.1 - 7.8e-09 35.4 0.0 1.8e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 PSC74626.1 - 9.8e-09 34.9 0.2 1.8e-08 34.0 0.2 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 PSC74626.1 - 9.6e-06 25.9 0.2 0.013 15.8 0.1 2.5 1 1 1 2 2 2 2 AAA domain AAA_2 PF07724.14 PSC74626.1 - 1.8e-05 24.9 0.0 4.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 PSC74626.1 - 1.9e-05 24.0 0.0 3.4e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 PSC74626.1 - 4.4e-05 23.5 0.2 0.00032 20.7 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PSC74626.1 - 6.6e-05 23.4 0.4 0.0017 18.7 0.1 2.4 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 PSC74626.1 - 0.00095 18.9 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Prot_ATP_OB_N PF17758.1 PSC74626.1 - 0.00099 18.7 0.1 0.0035 17.0 0.0 1.9 2 0 0 2 2 1 1 Proteasomal ATPase OB N-terminal domain RNA_helicase PF00910.22 PSC74626.1 - 0.0065 16.8 0.0 0.015 15.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.6 PSC74626.1 - 0.017 15.7 0.0 0.042 14.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain ATPase PF06745.13 PSC74626.1 - 0.018 14.4 0.3 0.33 10.3 0.1 2.4 2 1 0 3 3 2 0 KaiC TIP49 PF06068.13 PSC74626.1 - 0.019 14.2 0.0 0.036 13.3 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 PSC74626.1 - 0.019 14.8 0.1 0.069 13.0 0.0 2.0 2 1 1 3 3 2 0 ATPase family associated with various cellular activities (AAA) IstB_IS21 PF01695.17 PSC74626.1 - 0.022 14.5 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NB-ARC PF00931.22 PSC74626.1 - 0.024 13.8 0.1 0.78 8.9 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain Sigma54_activat PF00158.26 PSC74626.1 - 0.042 13.6 0.0 0.18 11.5 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 PSC74626.1 - 0.043 14.1 0.1 0.3 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 PSC74626.1 - 0.05 13.3 0.3 0.13 11.9 0.3 1.8 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 PSC74626.1 - 0.051 13.6 0.0 0.087 12.8 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 PSC74626.1 - 0.055 13.4 0.1 0.29 11.0 0.0 2.0 1 1 1 2 2 2 0 NACHT domain Mg_chelatase PF01078.21 PSC74626.1 - 0.092 12.1 0.1 0.18 11.2 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 PSC74626.1 - 0.1 12.8 0.0 0.18 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PSC74626.1 - 0.1 12.1 0.1 0.3 10.6 0.1 1.8 1 1 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 PSC74626.1 - 0.2 11.2 1.0 0.95 9.0 0.2 2.2 1 1 1 2 2 2 0 AAA domain Chloroa_b-bind PF00504.21 PSC74627.1 - 0.0017 18.9 0.0 0.0029 18.2 0.0 1.4 1 0 0 1 1 1 1 Chlorophyll A-B binding protein EPL1 PF10513.9 PSC74628.1 - 2.8e-10 40.8 25.1 5.2e-10 39.9 22.7 2.7 2 1 0 2 2 2 1 Enhancer of polycomb-like MDM10 PF12519.8 PSC74628.1 - 0.00042 19.3 2.0 0.0007 18.6 2.0 1.2 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 SAPS PF04499.15 PSC74628.1 - 3 6.5 6.1 6.1 5.5 6.1 1.4 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein ECH_1 PF00378.20 PSC74629.1 - 2.7e-43 148.1 0.0 3.2e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PSC74629.1 - 4e-18 66.0 0.0 5e-18 65.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 PSC74629.1 - 0.064 13.2 0.1 3 7.8 0.0 2.2 2 0 0 2 2 2 0 Peptidase family S49 Carboxyl_trans PF01039.22 PSC74629.1 - 0.15 10.7 0.2 0.27 9.8 0.2 1.3 1 1 0 1 1 1 0 Carboxyl transferase domain Xan_ur_permease PF00860.20 PSC74630.1 - 4.8e-25 88.1 29.7 3.4e-16 58.9 14.2 3.1 3 0 0 3 3 3 3 Permease family UQ_con PF00179.26 PSC74631.1 - 1.4e-43 147.9 0.0 1.6e-43 147.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PSC74631.1 - 0.00054 19.7 0.0 0.00067 19.4 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 PSC74631.1 - 0.041 14.2 0.0 0.049 13.9 0.0 1.2 1 0 0 1 1 1 0 RWD domain UFC1 PF08694.11 PSC74631.1 - 0.083 12.5 0.0 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 UQ_con PF00179.26 PSC74632.1 - 4.7e-37 126.8 0.0 5.2e-37 126.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 PSC74632.1 - 0.00018 21.2 0.0 0.0002 21.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 PSC74632.1 - 0.029 14.7 0.0 0.034 14.4 0.0 1.2 1 0 0 1 1 1 0 RWD domain UFC1 PF08694.11 PSC74632.1 - 0.072 12.7 0.0 0.092 12.4 0.0 1.2 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Pkinase_Tyr PF07714.17 PSC74633.1 - 6.8e-22 78.0 0.0 2.9e-13 49.7 0.0 3.2 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PSC74633.1 - 2.5e-17 63.1 0.0 3.6e-12 46.2 0.0 3.2 2 1 0 2 2 2 2 Protein kinase domain PB1 PF00564.24 PSC74633.1 - 0.064 13.2 0.0 4.6 7.3 0.0 2.3 2 0 0 2 2 2 0 PB1 domain FAD-oxidase_C PF02913.19 PSC74634.1 - 3.2e-60 203.9 0.9 4.6e-60 203.3 0.9 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 PSC74634.1 - 4.4e-41 139.9 1.0 1.6e-40 138.0 1.0 2.0 1 0 0 1 1 1 1 FAD binding domain PC-Esterase PF13839.6 PSC74635.1 - 0.02 14.7 2.9 0.57 9.9 0.9 3.0 3 1 1 4 4 4 0 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Linker_histone PF00538.19 PSC74636.1 - 9.4e-18 64.4 0.3 9.4e-18 64.4 0.3 2.9 2 1 2 4 4 4 1 linker histone H1 and H5 family PCM1_C PF15717.5 PSC74636.1 - 6 5.4 12.1 7.8 5.1 12.1 1.1 1 0 0 1 1 1 0 Pericentriolar material 1 C terminus ALMT PF11744.8 PSC74636.1 - 6.5 5.5 10.8 7.8 5.2 10.8 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter ATP-synt_ab PF00006.25 PSC74637.1 - 8.5e-106 352.4 0.0 1.3e-105 351.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 PSC74637.1 - 1.4e-46 157.3 0.0 2.5e-46 156.5 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension Histone PF00125.24 PSC74637.1 - 4.3e-19 69.2 0.8 7.5e-19 68.4 0.8 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 ATP-synt_ab_N PF02874.23 PSC74637.1 - 1.7e-14 54.1 3.2 2.8e-14 53.4 2.1 2.0 2 0 0 2 2 2 1 ATP synthase alpha/beta family, beta-barrel domain YscO-like PF16789.5 PSC74637.1 - 0.028 14.4 3.8 0.079 13.0 0.1 2.2 2 0 0 2 2 2 0 YscO-like protein CBFD_NFYB_HMF PF00808.23 PSC74637.1 - 0.047 14.0 0.0 0.17 12.2 0.0 2.0 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 PSC74637.1 - 0.17 12.4 0.0 0.51 10.9 0.0 1.7 1 0 0 1 1 1 0 Transcription initiation factor TFIID subunit A Cu PF17563.2 PSC74637.1 - 5.4 7.3 5.4 5.5 7.3 3.0 2.2 2 0 0 2 2 2 0 Cupiennin HEAT PF02985.22 PSC74639.1 - 1.2 9.6 8.3 1.1 9.7 0.1 4.5 4 0 0 4 4 4 0 HEAT repeat Arm PF00514.23 PSC74639.1 - 1.6 8.9 8.5 4.9 7.3 0.1 4.6 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat Swi3 PF07962.12 PSC74640.1 - 0.087 12.8 0.1 0.93 9.5 0.1 2.1 2 0 0 2 2 2 0 Replication Fork Protection Component Swi3 Prp19 PF08606.11 PSC74641.1 - 4.1e-34 116.4 0.2 1.1e-33 115.0 0.2 1.8 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 PSC74641.1 - 1.9e-23 82.3 7.0 8.4e-05 23.3 0.0 6.9 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC74641.1 - 3.8e-10 39.9 0.1 0.1 12.9 0.0 5.1 1 1 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain zf-Nse PF11789.8 PSC74641.1 - 0.0002 21.1 0.1 0.0015 18.3 0.0 2.1 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit U-box PF04564.15 PSC74641.1 - 0.011 15.8 0.0 0.02 15.1 0.0 1.3 1 0 0 1 1 1 0 U-box domain Ge1_WD40 PF16529.5 PSC74641.1 - 0.035 13.1 0.8 7.7 5.4 0.0 3.2 1 1 3 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Cep57_CLD_2 PF14197.6 PSC74641.1 - 0.039 14.0 2.1 0.15 12.2 2.2 1.8 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 Coatomer_WDAD PF04053.14 PSC74642.1 - 4e-163 543.6 0.0 1.7e-162 541.5 0.0 1.8 2 0 0 2 2 2 1 Coatomer WD associated region WD40 PF00400.32 PSC74642.1 - 3.2e-38 129.0 8.7 7.2e-08 33.0 0.1 8.2 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC74642.1 - 5e-06 26.7 0.5 3.2 8.1 0.0 5.9 5 2 1 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_2 PF07719.17 PSC74642.1 - 0.034 14.3 0.1 0.39 10.9 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Clathrin PF00637.20 PSC74642.1 - 0.082 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Region in Clathrin and VPS Thioredoxin PF00085.20 PSC74643.1 - 9.7e-12 44.8 0.0 1.4e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PSC74643.1 - 0.0011 19.5 0.0 0.0019 18.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like domain PHP_C PF13263.6 PSC74643.1 - 0.096 12.4 0.1 7.2 6.4 0.0 2.3 2 0 0 2 2 2 0 PHP-associated UQ_con PF00179.26 PSC74644.1 - 1.5e-46 157.5 0.0 2.1e-46 157.0 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme ACP_syn_III_C PF08541.10 PSC74644.1 - 8.5e-38 128.4 0.1 8.5e-38 128.4 0.1 2.6 3 0 0 3 3 3 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 PSC74644.1 - 2.3e-30 104.3 3.0 3.1e-30 103.8 1.0 2.1 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Thiolase_N PF00108.23 PSC74644.1 - 1.3e-06 28.0 1.3 2e-05 24.1 0.4 2.1 2 0 0 2 2 2 1 Thiolase, N-terminal domain Prok-E2_B PF14461.6 PSC74644.1 - 0.00028 20.6 0.0 0.0006 19.5 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B Ketoacyl-synt_C PF02801.22 PSC74644.1 - 0.013 15.5 0.3 7.3 6.6 0.0 2.8 2 1 0 2 2 2 0 Beta-ketoacyl synthase, C-terminal domain RWD PF05773.22 PSC74644.1 - 0.029 14.6 0.0 0.049 13.9 0.0 1.3 1 0 0 1 1 1 0 RWD domain Chal_sti_synt_C PF02797.15 PSC74644.1 - 0.036 14.1 0.0 0.062 13.3 0.0 1.3 1 0 0 1 1 1 0 Chalcone and stilbene synthases, C-terminal domain SpoVAD PF07451.11 PSC74644.1 - 0.045 12.5 1.3 0.62 8.7 0.9 2.1 2 0 0 2 2 2 0 Stage V sporulation protein AD (SpoVAD) Thiolase_C PF02803.18 PSC74644.1 - 0.053 13.2 1.0 5.3 6.7 0.0 3.3 3 0 0 3 3 3 0 Thiolase, C-terminal domain Gp_dh_C PF02800.20 PSC74646.1 - 1.9e-66 222.5 1.2 3.4e-66 221.7 1.2 1.4 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 PSC74646.1 - 2.7e-33 114.3 0.1 9.3e-33 112.6 0.1 2.0 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Rpp20 PF12328.8 PSC74646.1 - 0.077 13.0 0.1 0.17 11.9 0.0 1.6 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P LysM PF01476.20 PSC74647.1 - 3.6e-31 107.0 0.0 2e-07 31.0 0.0 4.4 4 0 0 4 4 4 4 LysM domain Trypan_PARP PF05887.11 PSC74647.1 - 0.0007 19.6 15.0 0.0012 18.8 15.0 1.3 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) HEAT_EZ PF13513.6 PSC74648.1 - 1.8e-19 69.8 41.3 4.4e-11 43.1 0.2 11.7 10 1 2 12 12 12 5 HEAT-like repeat HEAT PF02985.22 PSC74648.1 - 9.7e-18 62.7 22.6 0.0041 17.3 0.1 9.2 10 0 0 10 10 9 6 HEAT repeat HEAT_2 PF13646.6 PSC74648.1 - 3.2e-12 46.7 10.9 0.00047 20.5 0.5 6.9 4 2 3 8 8 8 5 HEAT repeats Vac14_Fab1_bd PF12755.7 PSC74648.1 - 2.9e-11 43.8 0.0 0.0075 16.8 0.0 4.6 3 1 1 4 4 4 3 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 PSC74648.1 - 8e-11 41.7 0.0 2.3e-10 40.2 0.0 1.9 2 0 0 2 2 2 1 Importin-beta N-terminal domain DUF3437 PF11919.8 PSC74648.1 - 6.2e-06 26.0 0.1 0.18 11.7 0.0 4.0 4 0 0 4 4 4 2 Domain of unknown function (DUF3437) Cnd1 PF12717.7 PSC74648.1 - 1.1e-05 25.5 0.0 0.21 11.6 0.0 3.8 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 PSC74648.1 - 0.00045 18.9 0.0 0.056 12.0 0.0 3.1 4 1 1 5 5 5 1 Adaptin N terminal region CLASP_N PF12348.8 PSC74648.1 - 0.0028 17.3 0.1 10 5.6 0.0 4.2 3 3 1 4 4 4 1 CLASP N terminal Dopey_N PF04118.14 PSC74648.1 - 0.0081 15.3 0.0 0.016 14.3 0.0 1.4 1 0 0 1 1 1 1 Dopey, N-terminal UME PF08064.13 PSC74648.1 - 0.028 14.3 0.4 32 4.5 0.0 4.4 4 1 1 5 5 5 0 UME (NUC010) domain TAF6_C PF07571.13 PSC74648.1 - 0.11 12.8 0.0 11 6.5 0.0 3.4 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain Cohesin_HEAT PF12765.7 PSC74648.1 - 6 7.3 5.1 84 3.6 0.6 4.0 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion MBOAT PF03062.19 PSC74649.1 - 1.2e-33 116.9 16.6 1.2e-33 116.9 16.6 1.5 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Pkinase PF00069.25 PSC74650.1 - 7.1e-75 251.8 0.0 1.1e-74 251.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74650.1 - 2.7e-29 102.2 0.0 4.3e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase rve PF00665.26 PSC74650.1 - 1.2e-18 67.5 0.0 2.6e-18 66.3 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC74650.1 - 0.0091 15.8 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Kdo PF06293.14 PSC74650.1 - 0.062 12.7 0.4 0.13 11.6 0.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 PSC74650.1 - 0.12 11.3 0.1 0.2 10.6 0.1 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Oxysterol_BP PF01237.18 PSC74651.1 - 3.2e-06 26.2 0.0 6.1e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 Oxysterol-binding protein Complex1_LYR_2 PF13233.6 PSC74652.1 - 1.9e-05 25.3 0.1 2.5e-05 24.9 0.1 1.5 1 1 0 1 1 1 1 Complex1_LYR-like Arm-DNA-bind_3 PF13356.6 PSC74652.1 - 1.7 9.1 5.7 34 4.9 5.7 2.2 1 1 0 1 1 1 0 Arm DNA-binding domain DUF3720 PF12517.8 PSC74653.1 - 3.6 8.6 5.7 10 7.1 5.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3720) SecY PF00344.20 PSC74655.1 - 3.2e-24 85.7 0.0 1.4e-15 57.3 0.0 2.1 2 0 0 2 2 2 2 SecY translocase Abhydrolase_6 PF12697.7 PSC74655.1 - 1.1e-09 39.3 10.2 1.1e-09 39.3 10.2 2.9 2 1 1 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PSC74655.1 - 9.2e-06 25.5 0.2 2.5e-05 24.1 0.0 1.8 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC74655.1 - 9.1e-05 21.8 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 SnoaL PF07366.12 PSC74655.1 - 0.2 11.5 0.0 0.67 9.8 0.0 1.7 2 0 0 2 2 2 0 SnoaL-like polyketide cyclase DZR PF12773.7 PSC74656.1 - 0.034 14.2 1.5 0.1 12.6 1.5 1.8 1 0 0 1 1 1 0 Double zinc ribbon HNH PF01844.23 PSC74656.1 - 0.045 13.9 2.1 0.18 12.0 2.1 2.2 1 1 0 1 1 1 0 HNH endonuclease Mut7-C PF01927.16 PSC74656.1 - 0.063 13.4 0.4 0.11 12.6 0.4 1.4 1 0 0 1 1 1 0 Mut7-C RNAse domain Cytochrom_c3_2 PF14537.6 PSC74656.1 - 0.083 13.4 3.1 0.18 12.3 3.1 1.7 1 0 0 1 1 1 0 Cytochrome c3 DUF3223 PF11523.8 PSC74656.1 - 0.11 13.4 0.0 0.44 11.4 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3223) Zn-ribbon_8 PF09723.10 PSC74656.1 - 0.42 10.8 3.2 4.8 7.4 3.2 2.5 1 1 0 1 1 1 0 Zinc ribbon domain Cytochrome_C7 PF14522.6 PSC74656.1 - 0.52 10.4 4.6 1.6 8.8 4.3 2.0 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c F-box-like PF12937.7 PSC74657.1 - 1.7e-09 37.4 0.7 3.6e-09 36.4 0.7 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PSC74657.1 - 0.00088 19.1 1.3 0.0019 18.0 0.1 2.3 2 1 0 2 2 2 1 F-box domain LRR_4 PF12799.7 PSC74657.1 - 0.0021 18.4 1.5 52 4.4 0.3 5.1 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PSC74657.1 - 0.0029 17.9 4.1 18 6.4 0.0 6.0 7 0 0 7 7 7 1 Leucine Rich Repeat ketoacyl-synt PF00109.26 PSC74658.1 - 1.5e-54 185.3 1.6 5.2e-54 183.5 0.4 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 PSC74658.1 - 1.2e-34 118.8 1.0 2.7e-34 117.7 1.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Rubis-subs-bind PF09273.11 PSC74658.1 - 8.8e-23 81.4 0.4 1.5e-22 80.6 0.4 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Thiolase_N PF00108.23 PSC74658.1 - 0.0012 18.2 0.7 0.0039 16.6 0.1 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain OapA_N PF08525.11 PSC74658.1 - 0.15 12.1 0.7 0.33 10.9 0.7 1.6 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif ketoacyl-synt PF00109.26 PSC74659.1 - 1.5e-54 185.3 1.6 5.1e-54 183.5 0.4 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 PSC74659.1 - 1.2e-34 118.8 1.0 2.7e-34 117.7 1.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Rubis-subs-bind PF09273.11 PSC74659.1 - 8.8e-23 81.4 0.4 1.5e-22 80.6 0.4 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding Thiolase_N PF00108.23 PSC74659.1 - 0.0012 18.2 0.7 0.0039 16.6 0.1 2.0 2 0 0 2 2 2 1 Thiolase, N-terminal domain OapA_N PF08525.11 PSC74659.1 - 0.15 12.1 0.7 0.33 10.9 0.7 1.6 1 0 0 1 1 1 0 Opacity-associated protein A N-terminal motif DUF3322 PF11795.8 PSC74659.1 - 0.95 9.4 3.5 0.6 10.1 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria N-term (DUF3322) Polysacc_deac_1 PF01522.21 PSC74660.1 - 5.6e-06 26.3 1.8 3.5e-05 23.7 1.8 2.2 1 1 0 1 1 1 1 Polysaccharide deacetylase Ribonuc_2-5A PF06479.12 PSC74662.1 - 1.4e-37 128.7 0.0 2.1e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease 2-5A Pkinase PF00069.25 PSC74662.1 - 3.7e-34 118.3 0.0 7.4e-34 117.3 0.0 1.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74662.1 - 1.1e-24 87.1 0.0 2e-24 86.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase zf-CCCH PF00642.24 PSC74662.1 - 1.4e-17 63.1 16.1 2.2e-09 37.0 3.9 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) PQQ PF01011.21 PSC74662.1 - 3.3e-06 26.7 0.0 0.039 13.9 0.0 3.8 3 0 0 3 3 3 1 PQQ enzyme repeat zf_CCCH_4 PF18345.1 PSC74662.1 - 9.3e-06 25.5 29.2 0.00013 21.8 4.6 3.2 3 0 0 3 3 3 2 Zinc finger domain PQQ_2 PF13360.6 PSC74662.1 - 1e-05 25.2 0.4 0.0001 22.0 0.0 2.4 1 1 0 1 1 1 1 PQQ-like domain zf-CCCH_4 PF18044.1 PSC74662.1 - 1.5e-05 24.7 15.5 0.0013 18.5 2.6 2.6 2 0 0 2 2 2 2 CCCH-type zinc finger Kinase-like PF14531.6 PSC74662.1 - 0.00045 19.6 0.0 0.00081 18.8 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PSC74662.1 - 0.0033 16.8 0.0 0.0063 15.9 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2722 PF10846.8 PSC74662.1 - 0.0077 15.2 6.5 0.012 14.6 6.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) SprA-related PF12118.8 PSC74662.1 - 0.01 15.0 15.9 0.018 14.2 15.9 1.3 1 0 0 1 1 1 0 SprA-related family MFS_3 PF05977.13 PSC74662.1 - 0.035 12.5 4.8 0.064 11.6 4.8 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector APH PF01636.23 PSC74662.1 - 0.036 14.0 0.0 0.036 14.0 0.0 5.2 4 2 1 5 5 4 0 Phosphotransferase enzyme family DUF913 PF06025.12 PSC74662.1 - 0.043 12.8 1.2 0.066 12.2 1.2 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) zf-CCCH_2 PF14608.6 PSC74662.1 - 0.11 13.0 19.0 0.39 11.3 5.0 2.6 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Suf PF05843.14 PSC74662.1 - 1.4 8.8 8.5 2.3 8.1 8.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) CCDC53 PF10152.9 PSC74662.1 - 3.9 7.9 10.3 6.2 7.2 8.0 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Pkinase_fungal PF17667.1 PSC74662.1 - 4.4 6.0 6.3 28 3.3 6.3 1.9 1 1 0 1 1 1 0 Fungal protein kinase Presenilin PF01080.17 PSC74662.1 - 6.4 5.4 5.3 9.3 4.9 5.3 1.1 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 PSC74662.1 - 9.5 5.7 21.6 21 4.6 21.6 1.5 1 0 0 1 1 1 0 Spt20 family PHD PF00628.29 PSC74664.1 - 2.8e-08 33.5 9.3 2.8e-08 33.5 9.3 1.7 2 0 0 2 2 2 1 PHD-finger PHD_2 PF13831.6 PSC74664.1 - 5.1e-05 22.7 5.3 0.0001 21.8 5.3 1.5 1 0 0 1 1 1 1 PHD-finger zf-PHD-like PF15446.6 PSC74664.1 - 0.13 11.9 4.0 0.42 10.2 4.0 1.9 1 0 0 1 1 1 0 PHD/FYVE-zinc-finger like domain C1_2 PF03107.16 PSC74664.1 - 0.89 9.9 4.9 2 8.8 4.9 1.6 1 0 0 1 1 1 0 C1 domain Nucleotid_trans PF03407.16 PSC74665.1 - 2e-41 142.3 0.4 2.6e-41 141.9 0.4 1.1 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF4407 PF14362.6 PSC74665.1 - 0.045 13.1 0.3 0.045 13.1 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DivIC PF04977.15 PSC74665.1 - 0.049 13.4 0.4 0.099 12.4 0.4 1.4 1 0 0 1 1 1 0 Septum formation initiator LPP PF04728.13 PSC74665.1 - 0.053 13.9 2.7 0.14 12.5 2.7 1.7 1 0 0 1 1 1 0 Lipoprotein leucine-zipper DUF726 PF05277.12 PSC74665.1 - 5.2 5.9 5.3 8 5.3 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Bestrophin PF01062.21 PSC74666.1 - 6e-39 134.2 0.0 1.1e-38 133.4 0.0 1.4 1 1 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel EB_dh PF09459.10 PSC74666.1 - 0.12 12.4 0.1 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 Ethylbenzene dehydrogenase ELMO_CED12 PF04727.13 PSC74667.1 - 1.9e-31 109.6 0.0 1.1e-30 107.1 0.0 1.9 1 1 0 1 1 1 1 ELMO/CED-12 family DUF953 PF06110.11 PSC74668.1 - 6.6e-15 54.8 0.0 8.7e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 PSC74668.1 - 0.0056 16.4 0.0 0.0099 15.7 0.0 1.4 2 0 0 2 2 2 1 Thioredoxin Thioredoxin PF00085.20 PSC74668.1 - 0.15 12.1 0.0 0.5 10.4 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_2 PF13098.6 PSC74668.1 - 0.16 12.4 0.2 1.1 9.7 0.2 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 PSC74668.1 - 0.2 11.8 0.1 0.2 11.8 0.1 1.8 2 1 0 2 2 2 0 Thioredoxin-like UBA_4 PF14555.6 PSC74669.1 - 2.9e-13 49.4 0.7 5.6e-13 48.5 0.7 1.5 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_7 PF13899.6 PSC74669.1 - 4.5e-12 46.0 0.0 7.8e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 PSC74669.1 - 5.2e-12 45.8 0.0 1.5e-11 44.4 0.0 1.7 2 0 0 2 2 2 1 UBX domain UIM PF02809.20 PSC74669.1 - 0.0001 22.0 0.6 0.0001 22.0 0.6 2.5 2 0 0 2 2 2 1 Ubiquitin interaction motif UBA PF00627.31 PSC74669.1 - 0.00024 20.9 3.0 0.0011 18.8 0.6 2.5 2 0 0 2 2 2 1 UBA/TS-N domain Chloroa_b-bind PF00504.21 PSC74670.1 - 0.0033 18.0 0.0 0.0035 17.9 0.0 1.2 1 0 0 1 1 1 1 Chlorophyll A-B binding protein Carboxyl_trans PF01039.22 PSC74671.1 - 3.5e-149 497.6 0.0 4.4e-149 497.3 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 PSC74671.1 - 1.7e-05 24.4 1.8 0.051 13.0 0.1 2.3 2 0 0 2 2 2 2 Malonate decarboxylase gamma subunit (MdcE) NAP PF00956.18 PSC74672.1 - 4.1e-67 226.2 6.9 4.1e-67 226.2 6.9 3.0 3 0 0 3 3 3 1 Nucleosome assembly protein (NAP) TLD PF07534.16 PSC74672.1 - 2.6e-34 118.4 0.0 3.7e-34 117.9 0.0 1.2 1 0 0 1 1 1 1 TLD RNA_polI_A34 PF08208.11 PSC74672.1 - 0.0061 16.7 5.7 0.0061 16.7 5.7 3.3 4 0 0 4 4 4 1 DNA-directed RNA polymerase I subunit RPA34.5 Sporozoite_P67 PF05642.11 PSC74672.1 - 0.079 11.0 26.4 0.061 11.4 14.4 2.4 2 0 0 2 2 2 0 Sporozoite P67 surface antigen NOA36 PF06524.12 PSC74672.1 - 0.75 9.1 38.7 0.63 9.3 12.4 3.3 3 0 0 3 3 3 0 NOA36 protein Peptidase_S8 PF00082.22 PSC74673.1 - 4.8e-114 380.6 30.1 3.6e-40 138.1 3.4 4.5 5 0 0 5 5 5 3 Subtilase family DUF4716 PF15837.5 PSC74673.1 - 0.0039 17.2 0.2 4.3 7.5 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4716) Peptidase_S8 PF00082.22 PSC74674.1 - 4.8e-114 380.6 30.1 3.6e-40 138.1 3.4 4.5 5 0 0 5 5 5 3 Subtilase family DUF4716 PF15837.5 PSC74674.1 - 0.0039 17.2 0.2 4.3 7.5 0.0 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4716) EF-hand_5 PF13202.6 PSC74676.1 - 5.5e-09 35.1 0.0 0.00044 19.6 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.32 PSC74676.1 - 1.1e-08 34.0 0.0 0.0014 18.0 0.0 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PSC74676.1 - 3.3e-07 29.7 0.0 0.00086 19.0 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 PSC74676.1 - 1.6e-06 28.4 0.0 0.03 14.8 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 PSC74676.1 - 0.0022 17.8 0.0 0.43 10.5 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair FG-GAP PF01839.23 PSC74676.1 - 0.039 14.1 0.5 1.5 9.0 0.1 2.4 2 0 0 2 2 2 0 FG-GAP repeat Dockerin_1 PF00404.18 PSC74676.1 - 0.12 12.6 0.0 4.6 7.5 0.0 2.1 2 0 0 2 2 2 0 Dockerin type I domain ACT PF01842.25 PSC74677.1 - 1e-15 57.2 0.0 1.9e-05 24.3 0.0 4.6 4 0 0 4 4 4 4 ACT domain ACT_6 PF13740.6 PSC74677.1 - 2.8e-07 30.4 0.3 0.0016 18.4 0.0 3.1 3 0 0 3 3 3 2 ACT domain ACT_4 PF13291.6 PSC74677.1 - 6.1e-06 26.7 0.0 1.1 9.9 0.0 4.3 4 0 0 4 4 4 2 ACT domain Kelch_2 PF07646.15 PSC74677.1 - 0.097 12.7 0.0 2.8 8.1 0.0 3.3 3 0 0 3 3 3 0 Kelch motif Ribosomal_L16 PF00252.18 PSC74678.1 - 3.1e-40 137.2 0.1 3.8e-40 137.0 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e DUF1490 PF07371.12 PSC74678.1 - 0.12 12.5 0.0 0.46 10.6 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) LSM14 PF12701.7 PSC74679.1 - 6.9e-29 99.8 0.0 1.2e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain Archease PF01951.16 PSC74679.1 - 7.6e-08 32.7 0.0 1.9e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) SM-ATX PF14438.6 PSC74679.1 - 0.0005 20.2 0.0 0.00093 19.3 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.10 PSC74679.1 - 0.0022 18.8 0.1 0.0022 18.8 0.1 4.3 3 2 1 4 4 4 2 FDF domain Spt20 PF12090.8 PSC74679.1 - 2.6 7.6 12.9 0.16 11.6 5.7 2.1 2 0 0 2 2 2 0 Spt20 family LSM14 PF12701.7 PSC74680.1 - 6.9e-29 99.8 0.0 1.2e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain Archease PF01951.16 PSC74680.1 - 7.6e-08 32.7 0.0 1.9e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) SM-ATX PF14438.6 PSC74680.1 - 0.0005 20.2 0.0 0.00093 19.3 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.10 PSC74680.1 - 0.0022 18.8 0.1 0.0022 18.8 0.1 4.3 3 2 1 4 4 4 2 FDF domain Spt20 PF12090.8 PSC74680.1 - 2.6 7.6 12.9 0.16 11.6 5.7 2.1 2 0 0 2 2 2 0 Spt20 family LSM14 PF12701.7 PSC74681.1 - 6.9e-29 99.8 0.0 1.2e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain Archease PF01951.16 PSC74681.1 - 7.6e-08 32.7 0.0 1.9e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) SM-ATX PF14438.6 PSC74681.1 - 0.0005 20.2 0.0 0.00093 19.3 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.10 PSC74681.1 - 0.0022 18.8 0.1 0.0022 18.8 0.1 4.3 3 2 1 4 4 4 2 FDF domain Spt20 PF12090.8 PSC74681.1 - 2.6 7.6 12.9 0.16 11.6 5.7 2.1 2 0 0 2 2 2 0 Spt20 family LSM14 PF12701.7 PSC74682.1 - 6.9e-29 99.8 0.0 1.2e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain Archease PF01951.16 PSC74682.1 - 7.6e-08 32.7 0.0 1.9e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) SM-ATX PF14438.6 PSC74682.1 - 0.0005 20.2 0.0 0.00093 19.3 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.10 PSC74682.1 - 0.0022 18.8 0.1 0.0022 18.8 0.1 4.3 3 2 1 4 4 4 2 FDF domain Spt20 PF12090.8 PSC74682.1 - 2.6 7.6 12.9 0.16 11.6 5.7 2.1 2 0 0 2 2 2 0 Spt20 family LSM14 PF12701.7 PSC74683.1 - 6.9e-29 99.8 0.0 1.2e-28 99.0 0.0 1.4 1 0 0 1 1 1 1 Scd6-like Sm domain Archease PF01951.16 PSC74683.1 - 7.6e-08 32.7 0.0 1.9e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) SM-ATX PF14438.6 PSC74683.1 - 0.0005 20.2 0.0 0.00093 19.3 0.0 1.4 1 0 0 1 1 1 1 Ataxin 2 SM domain FDF PF09532.10 PSC74683.1 - 0.0022 18.8 0.1 0.0022 18.8 0.1 4.2 3 2 1 4 4 4 2 FDF domain Spt20 PF12090.8 PSC74683.1 - 3.2 7.3 13.2 0.19 11.3 6.0 2.1 2 0 0 2 2 2 0 Spt20 family DXP_synthase_N PF13292.6 PSC74684.1 - 7.3e-113 376.3 0.8 1.3e-112 375.5 0.4 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Transket_pyr PF02779.24 PSC74684.1 - 1.8e-39 135.2 0.2 3.8e-39 134.2 0.2 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 PSC74684.1 - 6.1e-33 113.3 0.1 1.4e-32 112.2 0.0 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 PSC74684.1 - 1.8e-06 27.8 4.6 3.2e-06 27.0 0.9 2.8 2 1 1 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 PSC74684.1 - 4.2e-05 22.7 0.2 7.1e-05 21.9 0.2 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component Transketolase_N PF00456.21 PSC74684.1 - 6.4e-05 22.1 0.7 0.0016 17.4 0.5 2.8 1 1 1 2 2 2 1 Transketolase, thiamine diphosphate binding domain PRP3 PF08572.10 PSC74685.1 - 8.9e-63 212.0 5.3 8.9e-63 212.0 5.3 1.6 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 PSC74685.1 - 1e-34 119.7 0.0 2.4e-34 118.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1115) DLIC PF05783.11 PSC74685.1 - 0.95 8.2 2.7 1.7 7.4 2.7 1.4 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF3138 PF11336.8 PSC74685.1 - 5.1 5.6 13.9 11 4.5 13.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Thioesterase PF00975.20 PSC74686.1 - 2.3e-25 90.1 0.1 2.3e-25 90.1 0.1 1.6 2 0 0 2 2 2 1 Thioesterase domain Hydrolase_4 PF12146.8 PSC74686.1 - 0.071 12.4 0.3 0.15 11.3 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 DUF2201_N PF13203.6 PSC74686.1 - 1.5 8.4 7.9 0.065 12.8 1.1 2.0 2 0 0 2 2 2 0 Putative metallopeptidase domain DUF1771 PF08590.10 PSC74687.1 - 4.6e-10 39.7 12.7 4.6e-10 39.7 12.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 PSC74687.1 - 6.2e-08 32.9 0.0 2e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 Smr domain CUE PF02845.16 PSC74687.1 - 0.0069 16.1 0.0 1.8 8.3 0.0 2.7 2 0 0 2 2 2 2 CUE domain zf-ZPR1 PF03367.13 PSC74687.1 - 0.18 11.7 0.0 2.1 8.2 0.0 2.0 2 0 0 2 2 2 0 ZPR1 zinc-finger domain DMA PF03474.14 PSC74687.1 - 0.24 11.0 1.4 3.6 7.3 0.1 3.0 3 0 0 3 3 3 0 DMRTA motif DUF1771 PF08590.10 PSC74688.1 - 4.8e-10 39.7 12.7 4.8e-10 39.7 12.7 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 PSC74688.1 - 6.7e-08 32.8 0.0 2.1e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Smr domain CUE PF02845.16 PSC74688.1 - 0.0074 16.0 0.0 1.9 8.3 0.0 2.7 2 0 0 2 2 2 2 CUE domain zf-ZPR1 PF03367.13 PSC74688.1 - 0.2 11.5 0.0 2.2 8.1 0.0 2.0 2 0 0 2 2 2 0 ZPR1 zinc-finger domain DMA PF03474.14 PSC74688.1 - 0.27 10.9 1.4 3.8 7.2 0.1 2.9 3 0 0 3 3 3 0 DMRTA motif Pkinase PF00069.25 PSC74689.1 - 1.1e-59 202.0 0.0 8.2e-38 130.3 0.0 2.4 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74689.1 - 1.4e-23 83.5 0.0 7e-12 45.2 0.0 3.2 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 PSC74689.1 - 0.028 14.3 0.0 0.028 14.3 0.0 3.2 4 1 0 4 4 3 0 Phosphotransferase enzyme family Spt20 PF12090.8 PSC74689.1 - 0.046 13.3 20.8 0.094 12.3 20.8 1.4 1 0 0 1 1 1 0 Spt20 family Haspin_kinase PF12330.8 PSC74689.1 - 0.13 11.1 0.0 0.23 10.4 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain DUF4834 PF16118.5 PSC74689.1 - 0.53 11.3 7.3 1.6 9.8 7.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Suf PF05843.14 PSC74689.1 - 0.76 9.7 4.8 1.8 8.5 4.8 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 PSC74689.1 - 0.89 8.3 3.2 1.2 7.8 3.2 1.2 1 0 0 1 1 1 0 Presenilin eIF-3_zeta PF05091.12 PSC74689.1 - 1.3 7.9 6.5 1.9 7.4 6.5 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) MAJIN PF15077.6 PSC74689.1 - 1.6 8.5 3.8 3.5 7.4 3.8 1.6 1 0 0 1 1 1 0 Membrane-anchored junction protein Neur_chan_memb PF02932.16 PSC74689.1 - 3 7.8 5.1 9.7 6.2 2.1 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.9 PSC74689.1 - 5.7 5.1 12.2 8 4.6 12.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UPF0560 PF10577.9 PSC74689.1 - 6.4 5.1 10.3 9.4 4.6 10.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4336 PF14234.6 PSC74690.1 - 6.6e-28 97.8 0.0 3.8e-20 72.3 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4336) HTH_OrfB_IS605 PF12323.8 PSC74690.1 - 1 8.9 0.0 1 8.9 0.0 2.0 2 0 0 2 2 2 0 Helix-turn-helix domain Ank_2 PF12796.7 PSC74691.1 - 2.6e-23 82.4 2.9 1e-07 32.4 0.9 3.7 1 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC74691.1 - 8.3e-17 61.3 7.0 4.2e-09 36.8 0.1 5.2 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC74691.1 - 9e-14 50.3 12.2 0.16 12.6 0.1 7.1 7 0 0 7 7 6 5 Ankyrin repeat Ank_5 PF13857.6 PSC74691.1 - 4.2e-13 49.2 14.8 0.00035 20.8 0.1 6.2 3 2 3 6 6 6 4 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 PSC74691.1 - 3.1e-08 33.4 7.4 1.5e-07 31.1 7.4 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank PF00023.30 PSC74691.1 - 3.5e-06 27.2 30.1 0.041 14.4 0.1 7.2 8 0 0 8 8 6 3 Ankyrin repeat zf-C3HC4 PF00097.25 PSC74691.1 - 0.00042 20.1 7.7 0.00047 20.0 5.7 2.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC74691.1 - 0.0022 18.3 9.9 0.0071 16.7 9.9 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 PSC74691.1 - 0.036 14.1 5.0 0.11 12.6 5.0 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PSC74691.1 - 0.054 13.7 7.9 0.19 11.9 8.0 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Mating_C PF12737.7 PSC74691.1 - 0.055 12.7 6.5 0.099 11.9 6.5 1.3 1 0 0 1 1 1 0 C-terminal domain of homeodomain 1 zf-RING_5 PF14634.6 PSC74691.1 - 0.13 12.3 6.8 0.095 12.7 4.5 2.0 2 1 0 2 2 2 0 zinc-RING finger domain REV PF00424.18 PSC74691.1 - 0.35 10.9 4.8 3.6 7.7 1.6 2.5 2 0 0 2 2 2 0 REV protein (anti-repression trans-activator protein) Prok-RING_4 PF14447.6 PSC74691.1 - 1.6 8.6 11.1 20 5.1 11.2 2.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PSC74691.1 - 2.1 8.2 16.4 0.031 14.1 6.7 2.7 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Lipase_GDSL_2 PF13472.6 PSC74692.1 - 6e-09 36.5 0.0 1.2e-08 35.6 0.0 1.5 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family HSP70 PF00012.20 PSC74693.1 - 4.9e-260 863.9 7.7 5.5e-260 863.7 7.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PSC74693.1 - 4.3e-16 58.7 0.2 4.7e-15 55.2 0.1 2.3 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 PSC74693.1 - 0.0094 15.7 0.0 0.021 14.5 0.0 1.6 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 PSC74693.1 - 0.044 13.0 0.2 0.13 11.4 0.1 1.9 2 0 0 2 2 2 0 Hydantoinase/oxoprolinase PglZ PF08665.12 PSC74693.1 - 0.26 11.4 1.9 0.52 10.4 1.9 1.5 1 0 0 1 1 1 0 PglZ domain Alg14 PF08660.11 PSC74694.1 - 1.1e-55 188.3 0.0 3.7e-42 144.2 0.1 2.1 2 0 0 2 2 2 2 Oligosaccharide biosynthesis protein Alg14 like DUF4778 PF16008.5 PSC74695.1 - 0.58 10.2 7.4 1.2 9.2 7.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) DUF4551 PF15087.6 PSC74695.1 - 1.6 7.4 10.4 2.9 6.6 10.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Aminotran_5 PF00266.19 PSC74696.1 - 1.4e-43 149.3 0.0 2e-43 148.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V ABC1 PF03109.16 PSC74696.1 - 5.9e-30 103.9 0.0 1e-29 103.1 0.0 1.4 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 PSC74696.1 - 0.0052 16.7 0.1 0.0052 16.7 0.1 3.5 3 2 1 4 4 4 1 Phosphotransferase enzyme family AlaDh_PNT_C PF01262.21 PSC74696.1 - 0.052 12.8 0.1 0.052 12.8 0.1 1.6 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain WaaY PF06176.11 PSC74696.1 - 0.056 13.1 0.0 0.089 12.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) zf-RING_2 PF13639.6 PSC74697.1 - 1.5e-07 31.6 4.2 1.5e-07 31.6 4.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PSC74697.1 - 2.5e-06 27.2 6.2 2.5e-06 27.2 6.2 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC74697.1 - 2e-05 24.3 2.2 2e-05 24.3 2.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC74697.1 - 0.0002 21.1 4.5 0.0002 21.1 4.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC74697.1 - 0.0012 18.7 3.6 0.0012 18.7 3.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.7 PSC74697.1 - 0.0018 18.5 2.8 0.0018 18.5 2.8 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain CrgA PF06781.12 PSC74697.1 - 0.0033 17.5 0.0 0.0058 16.7 0.0 1.3 1 0 0 1 1 1 1 Cell division protein CrgA zf-RING_11 PF17123.5 PSC74697.1 - 0.0046 16.7 2.8 0.0046 16.7 2.8 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 PSC74697.1 - 0.0066 16.5 5.3 0.0066 16.5 5.3 1.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 PSC74697.1 - 0.016 15.3 7.4 0.04 14.0 1.5 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 PSC74697.1 - 0.84 9.5 10.0 2.4 8.0 1.2 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Macro PF01661.21 PSC74698.1 - 6.9e-40 135.8 0.0 8.9e-40 135.4 0.0 1.1 1 0 0 1 1 1 1 Macro domain SQS_PSY PF00494.19 PSC74699.1 - 4e-68 229.8 1.7 5.9e-68 229.2 1.7 1.3 1 0 0 1 1 1 1 Squalene/phytoene synthase W2 PF02020.18 PSC74700.1 - 1.4e-17 63.6 4.1 3.5e-17 62.3 4.1 1.7 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 PSC74700.1 - 0.029 14.1 11.5 3.1 7.7 0.0 4.5 2 1 2 4 4 4 0 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 PSC74700.1 - 0.053 12.5 0.3 0.08 11.9 0.3 1.2 1 0 0 1 1 1 0 L-fucokinase DUF4954 PF16314.5 PSC74700.1 - 0.055 11.6 0.5 0.099 10.7 0.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 PSC74700.1 - 0.29 10.9 4.6 9.3 6.1 0.8 4.0 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase A_deaminase PF00962.22 PSC74701.1 - 3.4e-37 128.5 0.0 4.5e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Aminotran_1_2 PF00155.21 PSC74701.1 - 7e-21 74.8 0.0 1e-20 74.2 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DNA_mis_repair PF01119.19 PSC74702.1 - 1.2e-29 102.3 0.0 1.8e-29 101.8 0.0 1.3 1 0 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain Pro_isomerase PF00160.21 PSC74703.1 - 2.4e-50 170.9 0.0 4.1e-50 170.1 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.12 PSC74703.1 - 0.0039 16.6 0.5 0.013 14.9 0.0 2.0 2 0 0 2 2 2 1 Rtf2 RING-finger mTERF PF02536.14 PSC74704.1 - 8.8e-07 28.1 0.0 0.00015 20.8 0.0 2.8 2 1 1 3 3 3 2 mTERF MFS_1 PF07690.16 PSC74705.1 - 6.7e-38 130.5 36.1 6.7e-38 130.5 36.1 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily PTR2 PF00854.21 PSC74705.1 - 0.01 14.7 0.9 0.018 13.9 0.9 1.3 1 0 0 1 1 1 0 POT family F-box-like PF12937.7 PSC74705.1 - 0.017 15.0 1.5 0.02 14.8 0.1 1.9 2 0 0 2 2 2 0 F-box-like MFS_1 PF07690.16 PSC74706.1 - 6.5e-38 130.5 36.1 6.5e-38 130.5 36.1 2.7 2 1 0 2 2 2 1 Major Facilitator Superfamily PTR2 PF00854.21 PSC74706.1 - 0.01 14.7 0.9 0.018 13.9 0.9 1.3 1 0 0 1 1 1 0 POT family F-box-like PF12937.7 PSC74706.1 - 0.017 15.0 1.5 0.02 14.8 0.1 1.9 2 0 0 2 2 2 0 F-box-like RWP-RK PF02042.15 PSC74707.1 - 7.3e-17 61.1 0.0 1.9e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 RWP-RK domain GATA PF00320.27 PSC74707.1 - 3.3e-13 49.0 4.4 8.3e-13 47.7 4.4 1.7 1 0 0 1 1 1 1 GATA zinc finger DUF2459 PF09601.10 PSC74707.1 - 0.24 11.2 2.1 0.61 9.9 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2459) DZR PF12773.7 PSC74707.1 - 2.7 8.1 4.1 8.7 6.5 4.1 1.9 1 0 0 1 1 1 0 Double zinc ribbon RRM_1 PF00076.22 PSC74708.1 - 1.4e-36 124.1 0.0 4.3e-18 64.9 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SF1-HH PF16275.5 PSC74708.1 - 2.7e-25 88.9 0.6 4.9e-25 88.1 0.1 1.8 2 0 0 2 2 2 1 Splicing factor 1 helix-hairpin domain Utp12 PF04003.12 PSC74708.1 - 5.2e-18 65.3 0.9 5.2e-18 65.3 0.9 1.7 2 0 0 2 2 2 1 Dip2/Utp12 Family KH_1 PF00013.29 PSC74708.1 - 1.8e-09 37.3 0.1 3.3e-09 36.5 0.1 1.4 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.23 PSC74708.1 - 9.6e-06 25.4 0.7 2.3e-05 24.3 0.7 1.7 1 0 0 1 1 1 1 Zinc knuckle RRM_7 PF16367.5 PSC74708.1 - 2.6e-05 24.2 0.0 0.01 15.9 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif TPPK_C PF12555.8 PSC74708.1 - 0.0087 16.1 0.2 0.017 15.2 0.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphokinase C terminal zf-CCHC_4 PF14392.6 PSC74708.1 - 0.035 13.8 0.6 0.067 12.9 0.6 1.5 1 0 0 1 1 1 0 Zinc knuckle Ribosomal_L30_N PF08079.12 PSC74709.1 - 4.5e-29 100.5 11.6 1e-28 99.4 11.6 1.6 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 PSC74709.1 - 3.8e-20 71.5 1.9 3.8e-20 71.5 1.9 2.1 2 1 0 2 2 2 1 Ribosomal protein L30p/L7e DUF1990 PF09348.10 PSC74709.1 - 0.083 12.9 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1990) BRCA-2_OB1 PF09103.10 PSC74710.1 - 1.4e-22 80.0 0.0 2.8e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.10 PSC74710.1 - 3.9e-06 26.7 0.0 3.9e-06 26.7 0.0 2.5 3 0 0 3 3 3 1 BRCA2, helical MEKHLA PF08670.11 PSC74712.1 - 4.3e-35 120.7 0.9 2.7e-34 118.1 0.0 2.1 2 0 0 2 2 2 1 MEKHLA domain WHEP-TRS PF00458.20 PSC74712.1 - 0.0012 18.9 0.4 0.0034 17.5 0.4 1.7 1 0 0 1 1 1 1 WHEP-TRS domain TRAM_LAG1_CLN8 PF03798.16 PSC74713.1 - 2e-29 102.8 0.7 2.4e-29 102.5 0.7 1.1 1 0 0 1 1 1 1 TLC domain GPI2 PF06432.11 PSC74713.1 - 0.0022 17.5 2.2 0.049 13.1 0.2 2.2 1 1 1 2 2 2 2 Phosphatidylinositol N-acetylglucosaminyltransferase Ribosomal_S17_N PF16205.5 PSC74714.1 - 8.6e-30 102.9 0.5 1.6e-29 102.1 0.5 1.4 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 PSC74714.1 - 2.7e-28 97.9 0.6 2.7e-28 97.9 0.6 1.5 2 0 0 2 2 2 1 Ribosomal protein S17 ABC_tran PF00005.27 PSC74715.1 - 1.8e-46 158.1 0.0 7.2e-24 84.9 0.0 3.1 2 2 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 PSC74715.1 - 4.3e-15 56.3 0.2 0.012 15.5 0.0 4.3 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PSC74715.1 - 8.1e-13 48.3 0.3 0.00075 19.0 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PSC74715.1 - 1.7e-07 30.8 0.3 0.017 14.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_28 PF13521.6 PSC74715.1 - 1.3e-06 28.8 0.0 0.0061 16.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 PSC74715.1 - 7.4e-06 26.0 0.0 0.036 14.1 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PSC74715.1 - 1.5e-05 24.9 0.1 0.066 13.1 0.1 2.4 2 0 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 PSC74715.1 - 2.7e-05 24.8 4.5 0.024 15.1 0.0 3.1 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 PSC74715.1 - 0.00014 22.1 0.0 1.4 9.2 0.0 4.1 5 0 0 5 5 4 1 AAA domain DUF87 PF01935.17 PSC74715.1 - 0.00024 21.3 0.3 0.048 13.8 0.2 2.6 2 0 0 2 2 2 1 Helicase HerA, central domain MeaB PF03308.16 PSC74715.1 - 0.00028 20.0 1.2 0.4 9.6 0.1 2.4 2 0 0 2 2 2 2 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF815 PF05673.13 PSC74715.1 - 0.00074 18.7 0.0 0.57 9.3 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.12 PSC74715.1 - 0.00075 19.4 0.1 0.76 9.7 0.0 2.9 3 0 0 3 3 2 1 NACHT domain AAA_33 PF13671.6 PSC74715.1 - 0.0015 18.7 0.1 3.5 7.8 0.0 3.0 2 0 0 2 2 2 2 AAA domain 4HB PF17947.1 PSC74715.1 - 0.002 18.2 0.0 0.0061 16.6 0.0 1.9 1 0 0 1 1 1 1 Four helical bundle domain AAA_15 PF13175.6 PSC74715.1 - 0.0026 17.6 0.1 0.88 9.2 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.6 PSC74715.1 - 0.0027 18.1 4.7 0.11 12.8 0.0 3.8 4 0 0 4 4 3 1 AAA ATPase domain AAA_18 PF13238.6 PSC74715.1 - 0.0027 18.3 0.0 4.4 7.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain FAM199X PF15814.5 PSC74715.1 - 0.007 15.5 4.5 0.013 14.6 4.5 1.4 1 0 0 1 1 1 1 Protein family FAM199X RNA_helicase PF00910.22 PSC74715.1 - 0.0073 16.7 0.0 3.6 8.0 0.0 2.5 2 0 0 2 2 2 1 RNA helicase Dynamin_N PF00350.23 PSC74715.1 - 0.0084 16.2 0.0 0.46 10.5 0.0 2.4 2 0 0 2 2 2 1 Dynamin family AAA_24 PF13479.6 PSC74715.1 - 0.0089 15.8 0.0 2 8.1 0.1 2.5 2 0 0 2 2 2 1 AAA domain ATP-synt_ab PF00006.25 PSC74715.1 - 0.0089 15.7 0.0 2.9 7.5 0.0 2.6 2 0 0 2 2 2 1 ATP synthase alpha/beta family, nucleotide-binding domain Zeta_toxin PF06414.12 PSC74715.1 - 0.019 14.2 1.1 2.4 7.4 0.0 2.9 3 0 0 3 3 3 0 Zeta toxin Roc PF08477.13 PSC74715.1 - 0.026 14.7 0.0 9.6 6.5 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Chromo PF00385.24 PSC74715.1 - 0.033 14.1 0.2 0.08 12.9 0.2 1.6 1 0 0 1 1 1 0 Chromo (CHRromatin Organisation MOdifier) domain PduV-EutP PF10662.9 PSC74715.1 - 0.055 13.2 0.0 2.4 7.9 0.0 2.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 PSC74715.1 - 0.074 13.5 0.1 9.3 6.7 0.0 3.0 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) DUF1995 PF09353.10 PSC74715.1 - 0.076 13.0 0.4 0.19 11.8 0.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1995) Arf PF00025.21 PSC74715.1 - 0.084 12.3 0.1 2.2 7.7 0.0 2.3 2 0 0 2 2 2 0 ADP-ribosylation factor family MukB PF04310.12 PSC74715.1 - 0.089 12.6 1.1 3.4 7.4 0.2 2.3 2 0 0 2 2 2 0 MukB N-terminal AAA_13 PF13166.6 PSC74715.1 - 0.095 11.3 0.1 8.6 4.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 PSC74715.1 - 0.099 12.2 3.2 2.6 7.6 0.1 2.8 3 0 0 3 3 2 0 AAA domain AAA_14 PF13173.6 PSC74715.1 - 0.13 12.3 0.0 30 4.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 PSC74715.1 - 0.15 12.0 0.3 20 5.2 0.1 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Septin PF00735.18 PSC74715.1 - 0.21 10.9 0.0 7.6 5.7 0.0 2.3 2 0 0 2 2 2 0 Septin HEAT PF02985.22 PSC74715.1 - 3.2 8.2 6.9 6.8 7.2 0.2 4.4 5 0 0 5 5 2 0 HEAT repeat Branch PF02485.21 PSC74716.1 - 2.2e-36 125.6 0.0 3.7e-36 124.9 0.0 1.3 1 0 0 1 1 1 1 Core-2/I-Branching enzyme TFIIA PF03153.13 PSC74716.1 - 0.93 9.4 21.7 1 9.3 14.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Cullin PF00888.22 PSC74717.1 - 6.6e-164 546.9 0.0 8e-164 546.6 0.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 PSC74717.1 - 1.7e-22 79.2 0.2 4e-22 78.0 0.2 1.7 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF4494 PF14902.6 PSC74717.1 - 0.049 13.5 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4494) SF3a60_bindingd PF12108.8 PSC74717.1 - 0.14 12.1 0.2 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain tRNA-synt_2b PF00587.25 PSC74718.1 - 5.7e-38 130.7 0.0 1.2e-37 129.6 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 PSC74718.1 - 3e-16 59.3 0.1 6.3e-16 58.3 0.1 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 PSC74718.1 - 1.1e-09 38.3 0.0 4.9e-09 36.1 0.0 2.2 2 0 0 2 2 2 1 Threonyl and Alanyl tRNA synthetase second additional domain DUF2057 PF09829.9 PSC74718.1 - 2.2 8.4 6.2 4.4 7.4 6.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) DUF4298 PF14131.6 PSC74719.1 - 0.05 13.6 0.2 0.061 13.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) zf_CCCH_5 PF18384.1 PSC74719.1 - 0.086 13.0 1.3 0.12 12.5 1.3 1.2 1 0 0 1 1 1 0 Unkempt Zinc finger domain 1 (Znf1) Epimerase PF01370.21 PSC74720.1 - 1.9e-24 86.5 0.1 3e-24 85.8 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 PSC74720.1 - 4e-20 72.5 0.0 1.7e-19 70.4 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 PSC74720.1 - 2.4e-05 23.6 0.0 0.0018 17.5 0.0 2.2 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein UDPG_MGDP_dh_N PF03721.14 PSC74720.1 - 0.12 11.9 0.1 0.25 10.9 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain DUF5539 PF17693.1 PSC74720.1 - 6.8 6.3 8.2 10 5.7 8.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5539) DHDPS PF00701.22 PSC74721.1 - 5.1e-79 265.0 0.0 6.2e-79 264.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrodipicolinate synthetase family Pkinase PF00069.25 PSC74722.1 - 1.1e-23 84.0 0.0 5.4e-23 81.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74722.1 - 5.2e-19 68.5 0.0 3.6e-18 65.8 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 PSC74722.1 - 1.1e-11 44.9 0.0 1.7e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 PSC74722.1 - 1.7e-07 31.4 0.0 3.3e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain APH PF01636.23 PSC74722.1 - 0.058 13.3 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PSC74722.1 - 0.069 11.9 0.0 0.098 11.4 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase HARE-HTH PF05066.13 PSC74723.1 - 2.7e-23 82.1 0.0 4.7e-23 81.4 0.0 1.4 1 0 0 1 1 1 1 HB1, ASXL, restriction endonuclease HTH domain TFIIA PF03153.13 PSC74723.1 - 0.78 9.7 16.0 1.3 9.0 16.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MA3 PF02847.17 PSC74724.1 - 6.6e-75 248.4 0.0 3.9e-21 75.1 0.1 4.1 4 0 0 4 4 4 4 MA3 domain PUB_1 PF18486.1 PSC74726.1 - 0.069 13.0 0.1 0.19 11.6 0.0 1.7 2 0 0 2 2 2 0 PNGase/UBA- or UBX-containing domain Methyltransf_11 PF08241.12 PSC74727.1 - 1.3e-13 51.3 0.0 6.5e-13 49.1 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC74727.1 - 3.4e-12 46.9 2.5 7.6e-12 45.8 0.1 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC74727.1 - 7e-06 26.7 0.0 8e-05 23.3 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC74727.1 - 0.00038 19.9 0.0 0.00085 18.7 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 PSC74727.1 - 0.01 15.7 0.7 0.033 14.0 0.0 2.2 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 PSC74727.1 - 0.058 13.2 0.0 0.058 13.2 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase domain Myb_DNA-bind_6 PF13921.6 PSC74728.1 - 2.9e-40 136.3 5.1 8.7e-18 64.3 0.1 3.5 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 PSC74728.1 - 1.7e-39 133.8 19.7 3.5e-16 59.1 0.6 3.8 4 0 0 4 4 4 3 Myb-like DNA-binding domain Rap1_C PF11626.8 PSC74728.1 - 0.0099 15.9 4.1 0.016 15.3 0.8 2.8 2 1 0 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain SANT_DAMP1_like PF16282.5 PSC74728.1 - 0.2 11.9 3.2 7.4 6.8 0.0 2.6 2 1 1 3 3 3 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 PSC74728.1 - 3.1 8.2 8.1 13 6.3 0.1 3.6 3 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PSC74728.1 - 5 7.1 5.7 43 4.1 0.0 3.6 3 1 2 5 5 5 0 Myb DNA-binding like Peptidase_M20 PF01546.28 PSC74730.1 - 6.1e-31 107.7 0.1 1.2e-30 106.7 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 PSC74730.1 - 3.3e-05 23.7 0.0 3.3e-05 23.7 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 M20_dimer PF07687.14 PSC74730.1 - 0.0045 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF2052 PF09747.9 PSC74730.1 - 0.022 14.9 11.8 0.58 10.3 5.1 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) AAR2 PF05282.11 PSC74730.1 - 0.18 11.2 1.2 0.53 9.6 1.0 1.7 2 0 0 2 2 2 0 AAR2 protein FlaG PF03646.15 PSC74730.1 - 0.82 9.9 9.9 0.67 10.2 7.2 2.3 2 0 0 2 2 2 0 FlaG protein Pex14_N PF04695.13 PSC74730.1 - 0.88 10.2 9.5 2 9.0 9.5 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Het-C PF07217.11 PSC74730.1 - 0.97 7.9 4.2 1.4 7.3 4.2 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Presenilin PF01080.17 PSC74730.1 - 1 8.0 4.3 1.9 7.1 4.3 1.3 1 0 0 1 1 1 0 Presenilin Sec62 PF03839.16 PSC74730.1 - 3 7.3 3.7 5.2 6.5 3.7 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 CCDC53 PF10152.9 PSC74730.1 - 5.6 7.4 10.1 0.49 10.8 5.0 1.8 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex BSP_II PF05432.11 PSC74730.1 - 7.5 6.1 16.9 3.7 7.2 4.7 2.3 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) HSP90 PF00183.18 PSC74731.1 - 7.1e-182 605.9 0.2 9.1e-182 605.5 0.2 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 PSC74731.1 - 1.1e-12 48.4 0.1 2e-12 47.6 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PSC74731.1 - 1.7e-11 44.1 0.2 4.3e-11 42.8 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cas_APE2256 PF09651.10 PSC74731.1 - 0.12 12.3 0.4 0.37 10.7 0.4 1.9 1 1 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) Thioredoxin PF00085.20 PSC74733.1 - 1.1e-14 54.3 0.0 1.2e-14 54.1 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin OST3_OST6 PF04756.13 PSC74733.1 - 0.056 12.8 0.0 0.057 12.8 0.0 1.0 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family BLM10_mid PF16507.5 PSC74734.1 - 1.6e-34 119.5 0.0 1.8e-15 56.7 0.0 3.9 3 1 0 3 3 3 3 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 PSC74734.1 - 3.8e-23 81.2 0.6 2.2e-22 78.8 0.0 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) HEAT PF02985.22 PSC74734.1 - 0.00066 19.7 24.1 0.061 13.6 0.0 7.2 7 0 0 7 7 7 3 HEAT repeat Arm PF00514.23 PSC74734.1 - 0.0046 16.9 6.2 0.25 11.4 0.9 4.5 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat Metallophos PF00149.28 PSC74735.1 - 2.3e-73 247.0 0.6 2.9e-35 122.6 0.1 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase ABC_membrane PF00664.23 PSC74735.1 - 5.7e-12 45.8 16.6 8.6e-12 45.3 16.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region STPPase_N PF16891.5 PSC74735.1 - 3e-05 24.4 2.0 0.31 11.5 0.1 2.6 2 0 0 2 2 2 2 Serine-threonine protein phosphatase N-terminal domain AAA_16 PF13191.6 PSC74735.1 - 0.00016 22.1 0.1 0.013 15.9 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 PSC74735.1 - 0.001 19.6 0.0 0.0094 16.5 0.0 2.2 2 0 0 2 2 2 1 ABC transporter Metallophos_2 PF12850.7 PSC74735.1 - 0.0017 18.5 0.0 3.1 8.0 0.0 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain FBPase PF00316.20 PSC74735.1 - 0.019 14.4 0.2 0.035 13.6 0.2 1.3 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain Desulfoferrod_N PF06397.12 PSC74735.1 - 0.078 12.6 2.6 11 5.8 0.2 2.9 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF384 PF04064.13 PSC74735.1 - 0.11 12.4 1.9 17 5.3 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF384) REV1_C PF16727.5 PSC74735.1 - 0.17 12.3 1.6 32 5.0 0.1 3.0 3 0 0 3 3 3 0 DNA repair protein REV1 C-terminal domain DUF2244 PF10003.9 PSC74735.1 - 0.28 10.8 2.4 1 9.0 2.4 1.9 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) AlaDh_PNT_N PF05222.15 PSC74735.1 - 1 9.7 5.8 39 4.5 0.1 3.9 4 0 0 4 4 4 0 Alanine dehydrogenase/PNT, N-terminal domain Metallophos PF00149.28 PSC74736.1 - 2.3e-73 247.1 0.6 2.9e-35 122.6 0.1 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase ABC_membrane PF00664.23 PSC74736.1 - 5.7e-12 45.9 16.6 8.6e-12 45.3 16.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region STPPase_N PF16891.5 PSC74736.1 - 2.9e-05 24.4 2.0 0.31 11.5 0.1 2.6 2 0 0 2 2 2 2 Serine-threonine protein phosphatase N-terminal domain AAA_16 PF13191.6 PSC74736.1 - 0.00016 22.1 0.1 0.013 15.9 0.1 2.7 2 0 0 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 PSC74736.1 - 0.001 19.6 0.0 0.0093 16.5 0.0 2.2 2 0 0 2 2 2 1 ABC transporter Metallophos_2 PF12850.7 PSC74736.1 - 0.0017 18.6 0.0 3.1 8.0 0.0 2.4 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain FBPase PF00316.20 PSC74736.1 - 0.019 14.4 0.2 0.035 13.6 0.2 1.3 1 0 0 1 1 1 0 Fructose-1-6-bisphosphatase, N-terminal domain Desulfoferrod_N PF06397.12 PSC74736.1 - 0.077 12.6 2.6 11 5.8 0.2 2.9 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF384 PF04064.13 PSC74736.1 - 0.1 12.4 1.9 17 5.4 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF384) REV1_C PF16727.5 PSC74736.1 - 0.17 12.3 1.6 32 5.0 0.1 3.0 3 0 0 3 3 3 0 DNA repair protein REV1 C-terminal domain DUF2244 PF10003.9 PSC74736.1 - 0.28 10.8 2.4 1 9.1 2.4 1.9 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) AlaDh_PNT_N PF05222.15 PSC74736.1 - 0.98 9.7 5.8 39 4.5 0.1 3.9 4 0 0 4 4 4 0 Alanine dehydrogenase/PNT, N-terminal domain Rootletin PF15035.6 PSC74737.1 - 0.005 16.9 24.2 0.072 13.1 4.5 3.3 2 1 1 3 3 3 3 Ciliary rootlet component, centrosome cohesion KASH_CCD PF14662.6 PSC74737.1 - 0.0071 16.2 8.7 0.0071 16.2 8.7 3.5 2 2 1 3 3 3 1 Coiled-coil region of CCDC155 or KASH ATG16 PF08614.11 PSC74737.1 - 0.012 15.9 14.6 0.012 15.9 14.6 4.3 2 2 2 4 4 4 0 Autophagy protein 16 (ATG16) Fez1 PF06818.15 PSC74737.1 - 0.026 15.0 27.1 0.58 10.6 1.8 3.4 3 0 0 3 3 3 0 Fez1 DUF1664 PF07889.12 PSC74737.1 - 0.1 12.6 8.9 0.55 10.3 0.2 3.7 2 2 1 3 3 3 0 Protein of unknown function (DUF1664) Fib_alpha PF08702.10 PSC74737.1 - 0.11 12.7 6.9 3.9 7.6 0.2 3.4 2 1 2 4 4 4 0 Fibrinogen alpha/beta chain family MIP-T3_C PF17749.1 PSC74737.1 - 0.61 10.0 23.9 0.71 9.8 4.7 4.1 3 2 0 3 3 3 0 Microtubule-binding protein MIP-T3 C-terminal region Spc7 PF08317.11 PSC74737.1 - 1.5 7.6 33.0 0.23 10.3 3.6 3.8 2 1 2 4 4 4 0 Spc7 kinetochore protein CENP-F_leu_zip PF10473.9 PSC74737.1 - 2.3 8.2 21.3 0.83 9.7 3.6 3.8 4 1 0 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YabA PF06156.13 PSC74737.1 - 3.7 8.2 12.7 14 6.4 0.3 4.2 3 2 1 4 4 4 0 Initiation control protein YabA HAUS-augmin3 PF14932.6 PSC74737.1 - 4.8 6.7 35.0 0.021 14.4 6.1 3.6 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 UPF0242 PF06785.11 PSC74737.1 - 9.5 6.3 17.7 2.9 8.0 7.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DIM1 PF02966.16 PSC74738.1 - 1.5e-41 141.3 0.4 1.7e-41 141.1 0.4 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 LRR_4 PF12799.7 PSC74739.1 - 7.4e-22 77.1 9.3 0.15 12.5 0.0 9.3 6 3 2 9 9 9 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC74739.1 - 6.7e-18 64.2 18.2 0.021 14.6 0.1 7.8 6 2 3 9 9 9 8 Leucine rich repeat LRR_6 PF13516.6 PSC74739.1 - 4e-15 54.5 30.1 0.044 13.8 0.0 12.8 14 0 0 14 14 14 5 Leucine Rich repeat LRR_9 PF14580.6 PSC74739.1 - 4.3e-05 23.1 0.3 7.6 6.0 0.0 4.7 2 2 3 5 5 5 2 Leucine-rich repeat VirE_N PF08800.10 PSC74739.1 - 0.044 13.9 0.0 0.085 13.0 0.0 1.4 1 0 0 1 1 1 0 VirE N-terminal domain DUF563 PF04577.14 PSC74740.1 - 1.6e-13 51.3 0.0 2.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Tad PF13400.6 PSC74740.1 - 0.13 12.6 4.4 0.36 11.2 4.4 1.7 1 0 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like U-box PF04564.15 PSC74741.1 - 7.3e-17 61.3 0.0 1.2e-16 60.6 0.0 1.4 1 0 0 1 1 1 1 U-box domain CPSase_L_D2 PF02786.17 PSC74742.1 - 2.8e-77 259.0 0.1 5.2e-77 258.1 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 PSC74742.1 - 2.4e-43 147.2 0.2 8.3e-43 145.4 0.1 2.0 2 0 0 2 2 2 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 PSC74742.1 - 7.9e-36 122.4 0.0 1.6e-35 121.5 0.0 1.5 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 PSC74742.1 - 1.3e-17 63.4 1.0 3.3e-17 62.1 1.0 1.7 1 0 0 1 1 1 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 PSC74742.1 - 7.3e-09 35.5 0.0 1.5e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus Biotin_lipoyl_2 PF13533.6 PSC74742.1 - 2.4e-07 30.5 0.4 0.0013 18.5 0.1 3.2 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp PF02222.22 PSC74742.1 - 5.4e-06 26.1 0.1 9.6e-06 25.3 0.1 1.4 1 0 0 1 1 1 1 ATP-grasp domain HlyD_D23 PF16576.5 PSC74742.1 - 0.00037 19.8 0.3 0.58 9.3 0.0 2.4 1 1 1 2 2 2 2 Barrel-sandwich domain of CusB or HlyD membrane-fusion HlyD_3 PF13437.6 PSC74742.1 - 0.0004 21.0 1.4 0.59 10.9 0.1 2.6 2 0 0 2 2 2 2 HlyD family secretion protein GCV_H PF01597.19 PSC74742.1 - 0.038 13.9 0.0 0.082 12.8 0.0 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF2118 PF09891.9 PSC74742.1 - 0.041 13.8 0.3 0.12 12.3 0.3 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) ATP-grasp_3 PF02655.14 PSC74742.1 - 0.072 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Catalase-rel PF06628.12 PSC74743.1 - 0.083 13.1 0.0 2.4 8.4 0.0 2.3 1 1 1 2 2 2 0 Catalase-related immune-responsive Catalase-rel PF06628.12 PSC74744.1 - 0.077 13.2 0.0 2.3 8.5 0.0 2.2 1 1 1 2 2 2 0 Catalase-related immune-responsive TFIIA PF03153.13 PSC74745.1 - 0.076 13.0 32.2 0.091 12.7 32.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 PSC74745.1 - 1.2 7.4 21.7 1.2 7.4 21.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAT PF02259.23 PSC74747.1 - 2.4e-27 96.1 14.1 4.1e-27 95.3 14.1 1.3 1 0 0 1 1 1 1 FAT domain PI3_PI4_kinase PF00454.27 PSC74747.1 - 2.5e-12 47.2 0.0 4.5e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.20 PSC74747.1 - 3.9e-05 23.4 0.3 3.9e-05 23.4 0.3 2.6 3 0 0 3 3 3 1 FATC domain TPR_14 PF13428.6 PSC74747.1 - 0.0017 19.0 0.5 0.03 15.1 0.0 3.6 2 0 0 2 2 2 1 Tetratricopeptide repeat F-box-like PF12937.7 PSC74749.1 - 7.5e-09 35.3 0.2 1.9e-08 34.1 0.2 1.7 1 0 0 1 1 1 1 F-box-like WD40 PF00400.32 PSC74749.1 - 1.1e-06 29.2 1.1 0.82 10.7 0.0 3.9 3 0 0 3 3 3 2 WD domain, G-beta repeat F-box PF00646.33 PSC74749.1 - 4.4e-06 26.4 0.1 7.6e-06 25.7 0.1 1.4 1 0 0 1 1 1 1 F-box domain DUF2722 PF10846.8 PSC74749.1 - 0.00096 18.2 15.5 0.0013 17.8 15.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Pex14_N PF04695.13 PSC74749.1 - 0.0014 19.3 10.0 0.0014 19.3 10.0 1.6 2 0 0 2 2 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIA PF03153.13 PSC74749.1 - 0.0035 17.4 21.1 0.0053 16.8 21.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Med15 PF09606.10 PSC74749.1 - 0.0043 15.8 17.0 0.0076 15.0 17.0 1.4 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DDHD PF02862.17 PSC74749.1 - 0.012 15.8 1.7 0.017 15.3 1.7 1.2 1 0 0 1 1 1 0 DDHD domain ANAPC4_WD40 PF12894.7 PSC74749.1 - 0.052 13.9 0.0 1.7 9.0 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_S15 PF02129.18 PSC74749.1 - 0.18 11.4 7.8 0.33 10.5 7.8 1.4 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) SpoIIP PF07454.11 PSC74749.1 - 0.49 9.8 6.0 0.68 9.3 6.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Band_3_cyto PF07565.13 PSC74749.1 - 0.57 9.9 7.1 0.84 9.4 7.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain U1snRNP70_N PF12220.8 PSC74749.1 - 0.6 10.8 10.1 1 10.0 10.1 1.3 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Suf PF05843.14 PSC74749.1 - 0.74 9.7 13.2 1.1 9.2 13.2 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Neur_chan_memb PF02932.16 PSC74749.1 - 0.78 9.7 4.1 1.1 9.2 4.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EPL1 PF10513.9 PSC74749.1 - 0.84 10.0 7.5 1.2 9.5 7.5 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like WBP-1 PF11669.8 PSC74749.1 - 0.88 10.2 3.1 2.1 9.0 3.1 1.6 1 0 0 1 1 1 0 WW domain-binding protein 1 V_ATPase_I PF01496.19 PSC74749.1 - 1 7.2 5.9 1.3 6.8 5.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ALMT PF11744.8 PSC74749.1 - 1 8.1 3.3 1.3 7.7 3.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter PAT1 PF09770.9 PSC74749.1 - 1.4 7.1 16.0 1.9 6.7 16.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Spt20 PF12090.8 PSC74749.1 - 1.5 8.4 32.0 2.2 7.9 32.0 1.1 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 PSC74749.1 - 2.1 7.1 10.7 3.2 6.4 10.7 1.2 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 PSC74749.1 - 2.2 9.3 11.2 3.7 8.6 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Connexin PF00029.19 PSC74749.1 - 2.5 7.8 5.1 3.7 7.2 5.1 1.2 1 0 0 1 1 1 0 Connexin eIF-3_zeta PF05091.12 PSC74749.1 - 2.6 6.9 14.6 3.6 6.4 14.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Ndc1_Nup PF09531.10 PSC74749.1 - 2.8 6.5 10.8 4.1 6.0 10.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MDM10 PF12519.8 PSC74749.1 - 4.1 6.2 7.3 5.5 5.7 7.3 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 TERB2 PF15101.6 PSC74749.1 - 4.6 7.2 16.9 7 6.6 16.9 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 RR_TM4-6 PF06459.12 PSC74749.1 - 5.3 6.8 8.8 7.4 6.3 8.8 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4518 PF15008.6 PSC74749.1 - 9.5 5.3 12.5 14 4.8 12.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4518) HAD_2 PF13419.6 PSC74750.1 - 5.2e-18 65.7 0.0 8.7e-18 65.0 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PSC74750.1 - 1.4e-11 45.1 0.3 8.9e-11 42.5 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase PHD PF00628.29 PSC74750.1 - 5e-08 32.7 5.4 8.8e-08 31.9 5.4 1.4 1 0 0 1 1 1 1 PHD-finger zf-MIZ PF02891.20 PSC74750.1 - 3.1e-07 30.0 0.0 1.2e-06 28.1 0.0 2.0 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger Hydrolase_like PF13242.6 PSC74750.1 - 8.2e-06 25.8 0.0 3e-05 24.0 0.0 2.0 2 0 0 2 2 2 1 HAD-hyrolase-like SAP PF02037.27 PSC74750.1 - 0.00044 19.9 0.2 0.0011 18.7 0.2 1.6 1 0 0 1 1 1 1 SAP domain PINIT PF14324.6 PSC74750.1 - 0.057 13.8 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 PINIT domain zf-HC5HC2H PF13771.6 PSC74750.1 - 0.74 10.1 2.9 1.6 9.0 2.9 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain TFIIA PF03153.13 PSC74750.1 - 9 6.2 21.2 6.5 6.6 7.9 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Nucleo_P87 PF07267.11 PSC74751.1 - 1.1 8.0 2.8 2.2 7.0 2.8 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Axin_b-cat_bind PF08833.10 PSC74751.1 - 5.6 7.1 7.7 1.5 9.0 2.3 2.8 2 0 0 2 2 2 0 Axin beta-catenin binding domain Chitin_synth_1 PF01644.17 PSC74752.1 - 1.3e-42 145.6 0.0 2.2e-42 144.8 0.0 1.4 1 0 0 1 1 1 1 Chitin synthase Chitin_synth_2 PF03142.15 PSC74752.1 - 2.5e-24 85.8 7.6 1.4e-20 73.4 0.4 3.1 2 1 0 3 3 3 2 Chitin synthase Chitin_synth_1N PF08407.11 PSC74752.1 - 1.1e-16 60.5 0.2 2.2e-16 59.6 0.2 1.5 1 0 0 1 1 1 1 Chitin synthase N-terminal Glyco_trans_2_3 PF13632.6 PSC74752.1 - 2.7e-13 50.3 1.8 2.7e-13 50.3 1.8 2.3 2 0 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_tranf_2_3 PF13641.6 PSC74752.1 - 7.2e-07 29.3 0.0 1.8e-06 28.0 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF2207 PF09972.9 PSC74752.1 - 0.032 13.0 0.1 0.032 13.0 0.1 2.8 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) EF-hand_7 PF13499.6 PSC74754.1 - 1.8e-25 89.2 0.0 1e-12 48.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PSC74754.1 - 9.9e-25 84.2 3.9 3e-05 23.3 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PSC74754.1 - 4.2e-20 69.9 5.2 1.2e-05 24.8 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.6 PSC74754.1 - 4.4e-20 71.3 0.1 3e-09 36.6 0.0 3.3 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 PSC74754.1 - 5e-19 66.9 5.9 0.00019 20.7 0.2 4.4 4 0 0 4 4 4 4 EF hand Mpv17_PMP22 PF04117.12 PSC74754.1 - 2.9e-15 56.2 0.0 5.2e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family EF-hand_9 PF14658.6 PSC74754.1 - 1.6e-06 28.4 0.0 0.0021 18.3 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain Pkinase PF00069.25 PSC74755.1 - 1.5e-29 103.2 0.0 1e-19 70.9 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74755.1 - 8.2e-26 90.8 0.0 1.5e-15 57.2 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase LRR_4 PF12799.7 PSC74755.1 - 4.9e-12 45.9 1.1 0.04 14.3 0.0 4.6 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC74755.1 - 5.7e-11 42.0 1.3 0.016 15.0 0.8 3.9 3 1 0 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 PSC74755.1 - 1.1e-07 31.4 6.8 1.9 9.4 0.1 6.6 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 PSC74755.1 - 0.001 19.0 9.4 2.6 8.3 0.2 6.1 6 0 0 6 6 6 1 Leucine Rich repeat LRRNT_2 PF08263.12 PSC74755.1 - 9 6.7 6.6 1.1e+02 3.2 6.6 2.6 1 1 0 1 1 1 0 Leucine rich repeat N-terminal domain Pkinase PF00069.25 PSC74756.1 - 1.5e-29 103.2 0.0 1e-19 70.9 0.0 2.8 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74756.1 - 9e-26 90.7 0.0 1.7e-15 57.1 0.0 2.8 2 1 0 2 2 2 2 Protein tyrosine kinase LRR_4 PF12799.7 PSC74756.1 - 4.8e-12 45.9 1.1 0.04 14.3 0.0 4.6 3 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC74756.1 - 5.7e-11 42.0 1.3 0.016 15.0 0.8 3.9 3 1 0 3 3 3 3 Leucine rich repeat LRR_1 PF00560.33 PSC74756.1 - 1.1e-07 31.4 6.8 1.9 9.4 0.1 6.6 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 PSC74756.1 - 0.00099 19.0 9.4 2.6 8.3 0.2 6.1 6 0 0 6 6 6 1 Leucine Rich repeat LRRNT_2 PF08263.12 PSC74756.1 - 9 6.7 6.6 1.1e+02 3.2 6.6 2.6 1 1 0 1 1 1 0 Leucine rich repeat N-terminal domain TAF8_C PF10406.9 PSC74757.1 - 2.4e-16 60.0 1.2 4.9e-16 59.0 1.2 1.6 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 PSC74757.1 - 2.4e-12 46.7 0.0 4.7e-12 45.7 0.0 1.5 1 0 0 1 1 1 1 Bromodomain associated F_actin_bind PF08919.10 PSC74758.1 - 0.0012 18.9 0.0 0.0088 16.1 0.0 2.6 1 0 0 1 1 1 1 F-actin binding UPF0561 PF10573.9 PSC74758.1 - 0.046 13.8 0.1 0.19 11.9 0.1 2.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0561 SBP PF03110.14 PSC74759.1 - 2.3e-21 75.9 13.3 2.3e-21 75.9 13.3 2.4 2 0 0 2 2 2 1 SBP domain DUF4541 PF15074.6 PSC74759.1 - 0.14 12.8 0.1 0.32 11.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4541) CxC6 PF18721.1 PSC74759.1 - 0.31 11.3 8.6 1.4 9.3 8.6 2.1 1 1 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases RNA_pol_Rpb1_5 PF04998.17 PSC74762.1 - 3.8e-83 279.0 0.0 6.1e-83 278.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 PSC74762.1 - 3.3e-53 180.3 0.0 5.5e-53 179.6 0.0 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 PSC74762.1 - 1.6e-33 115.8 0.0 3.3e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 PSC74762.1 - 1.7e-27 96.6 0.0 9.7e-24 84.3 0.0 2.4 2 0 0 2 2 2 2 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 PSC74762.1 - 1e-19 70.5 0.0 2.2e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 4 CDC27 PF09507.10 PSC74762.1 - 6.4 6.1 19.4 1.4 8.2 10.3 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Abhydrolase_1 PF00561.20 PSC74763.1 - 2.6e-26 92.8 0.1 8e-21 74.8 0.1 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PSC74763.1 - 3.9e-21 76.7 5.4 3.9e-21 76.7 5.4 2.3 2 1 0 2 2 2 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PSC74763.1 - 1.1e-11 44.5 0.9 1.1e-10 41.2 0.1 2.5 2 1 0 2 2 2 1 Serine aminopeptidase, S33 DUF2716 PF10898.8 PSC74763.1 - 0.083 13.3 0.4 0.62 10.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2716) Hemerythrin PF01814.23 PSC74763.1 - 0.2 12.3 2.2 0.3 11.7 1.1 1.9 2 0 0 2 2 2 0 Hemerythrin HHE cation binding domain Guanylate_cyc_2 PF09778.9 PSC74764.1 - 1.4e-46 158.6 0.0 4.9e-40 137.1 0.0 2.2 1 1 1 2 2 2 2 Guanylylate cyclase STIMATE PF12400.8 PSC74764.1 - 5.2e-18 65.8 0.0 3.1e-17 63.3 0.0 2.2 1 1 0 1 1 1 1 STIMATE family CCT PF06203.14 PSC74764.1 - 0.0013 18.8 0.2 0.003 17.6 0.2 1.5 1 0 0 1 1 1 1 CCT motif DUF3335 PF11814.8 PSC74764.1 - 0.026 14.0 0.1 0.11 11.9 0.1 1.9 1 1 0 1 1 1 0 Peptidase_C39 like family Peptidase_C39 PF03412.15 PSC74764.1 - 0.068 13.0 0.0 0.21 11.4 0.0 1.8 1 1 1 2 2 2 0 Peptidase C39 family ECH_1 PF00378.20 PSC74765.1 - 7.2e-44 150.0 0.0 7.7e-44 149.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PSC74765.1 - 4.6e-25 88.8 0.1 1.8e-20 73.7 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SBP PF03110.14 PSC74766.1 - 1e-24 86.6 6.2 1.8e-24 85.8 6.2 1.4 1 0 0 1 1 1 1 SBP domain RLL PF10036.9 PSC74766.1 - 0.066 13.1 1.4 0.091 12.6 0.1 1.7 2 0 0 2 2 2 0 RNA transcription, translation and transport factor protein Cep57_CLD_2 PF14197.6 PSC74766.1 - 0.14 12.3 2.2 2 8.5 0.1 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 CxC6 PF18721.1 PSC74766.1 - 0.25 11.7 10.5 2 8.7 10.5 2.2 1 1 0 1 1 1 0 CxC6 like cysteine cluster associated with KDZ transposases Macoilin PF09726.9 PSC74766.1 - 0.93 8.0 2.8 7.8 4.9 2.2 2.0 2 0 0 2 2 2 0 Macoilin family YabA PF06156.13 PSC74766.1 - 1.1 10.0 2.7 6.3 7.5 0.3 2.3 2 0 0 2 2 2 0 Initiation control protein YabA DUF4140 PF13600.6 PSC74766.1 - 1.3 9.6 5.2 21 5.7 0.0 3.4 3 0 0 3 3 3 0 N-terminal domain of unknown function (DUF4140) FA_desaturase PF00487.24 PSC74767.1 - 1.8e-32 113.1 23.6 4e-32 112.1 23.6 1.5 1 0 0 1 1 1 1 Fatty acid desaturase fn3 PF00041.21 PSC74767.1 - 3.5e-22 78.6 0.0 7.3e-07 29.4 0.0 4.4 4 0 0 4 4 4 4 Fibronectin type III domain DUF3474 PF11960.8 PSC74767.1 - 1.7e-05 25.0 0.3 7.4e-05 23.0 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3474) DUF4959 PF16323.5 PSC74767.1 - 0.0015 18.8 0.0 0.69 10.3 0.0 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4959) SnoaL PF07366.12 PSC74767.1 - 0.0029 17.4 0.0 0.016 15.0 0.0 2.0 2 0 0 2 2 2 1 SnoaL-like polyketide cyclase RVT_2 PF07727.14 PSC74768.1 - 4.1e-54 183.8 0.0 6e-54 183.2 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Retrotran_gag_2 PF14223.6 PSC74768.1 - 2.9e-24 85.3 0.0 5.3e-24 84.5 0.0 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type rve PF00665.26 PSC74768.1 - 2.2e-23 82.7 0.0 6.8e-23 81.1 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 PSC74768.1 - 1.4e-08 34.5 0.0 2.8e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain PfkB PF00294.24 PSC74768.1 - 8.2e-07 28.6 0.8 1.7e-06 27.6 0.8 1.4 1 0 0 1 1 1 1 pfkB family carbohydrate kinase DUF4219 PF13961.6 PSC74768.1 - 5.3e-05 22.8 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4219) rve_3 PF13683.6 PSC74768.1 - 0.0025 17.5 0.0 0.0083 15.9 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain RVT_1 PF00078.27 PSC74768.1 - 0.0056 16.2 0.0 0.8 9.2 0.0 2.3 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) Asp_protease_2 PF13650.6 PSC74768.1 - 0.089 13.4 0.1 0.75 10.5 0.0 2.4 2 0 0 2 2 2 0 Aspartyl protease zf-C2H2_10 PF16588.5 PSC74768.1 - 0.16 11.8 2.0 0.32 10.7 2.0 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger Retrotran_gag_3 PF14244.6 PSC74768.1 - 0.2 11.5 0.0 0.48 10.3 0.0 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type WD40 PF00400.32 PSC74769.1 - 5.9e-58 191.5 30.2 9.8e-09 35.7 0.3 9.2 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC74769.1 - 1.2e-19 70.4 2.2 0.005 17.1 0.0 5.7 3 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 PSC74769.1 - 1.4e-12 47.9 0.0 2.5e-12 47.1 0.0 1.4 1 0 0 1 1 1 1 NLE (NUC135) domain Ge1_WD40 PF16529.5 PSC74769.1 - 8.8e-08 31.5 0.4 0.018 14.0 1.0 4.1 3 1 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PSC74769.1 - 9.1e-07 28.9 0.0 0.46 10.3 0.0 3.8 2 2 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A Frtz PF11768.8 PSC74769.1 - 0.00022 19.7 0.0 0.22 9.8 0.0 2.6 2 1 1 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 PSC74769.1 - 0.00029 20.3 0.0 3.7 6.8 0.0 3.5 4 0 0 4 4 4 2 WD40-like domain Cytochrom_D1 PF02239.16 PSC74769.1 - 0.0048 15.5 0.0 0.073 11.6 0.0 2.3 2 0 0 2 2 2 1 Cytochrome D1 heme domain Nbas_N PF15492.6 PSC74769.1 - 0.033 13.5 2.1 14 4.9 0.0 3.8 2 2 1 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Proteasome_A_N PF10584.9 PSC74769.1 - 0.12 12.1 2.9 21 4.9 0.0 3.7 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature PD40 PF07676.12 PSC74769.1 - 0.22 11.5 6.2 42 4.2 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat Nup160 PF11715.8 PSC74769.1 - 0.25 10.0 2.4 6.8 5.2 0.1 3.3 4 0 0 4 4 4 0 Nucleoporin Nup120/160 TAF6_C PF07571.13 PSC74770.1 - 7.1e-15 55.1 0.0 1.5e-14 54.1 0.0 1.6 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 PSC74770.1 - 0.0033 17.6 0.1 0.01 16.0 0.1 1.8 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Pkinase PF00069.25 PSC74771.1 - 2.3e-42 145.2 0.0 1.6e-41 142.4 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74771.1 - 5.8e-36 124.1 0.0 6.7e-35 120.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 PSC74771.1 - 0.02 14.8 0.3 0.077 12.9 0.3 1.9 1 1 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PSC74771.1 - 0.032 13.0 0.0 0.042 12.6 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Na_H_Exchanger PF00999.21 PSC74772.1 - 8.3e-24 84.1 19.3 8.3e-24 84.1 19.3 1.9 1 1 1 2 2 2 2 Sodium/hydrogen exchanger family Pkinase PF00069.25 PSC74773.1 - 5.9e-39 134.0 0.0 3e-38 131.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74773.1 - 8.6e-32 110.4 0.0 3.4e-31 108.5 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase LRR_8 PF13855.6 PSC74773.1 - 5.1e-12 45.4 0.0 7.2e-05 22.5 0.0 4.5 4 1 0 4 4 4 2 Leucine rich repeat LRR_4 PF12799.7 PSC74773.1 - 3.7e-11 43.1 0.0 0.0017 18.7 0.1 4.6 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PSC74773.1 - 0.01 16.3 0.5 93 4.2 0.0 4.2 3 0 0 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.6 PSC74773.1 - 0.043 13.9 3.6 38 4.7 0.1 4.8 4 0 0 4 4 4 0 Leucine Rich repeat Pkinase_fungal PF17667.1 PSC74773.1 - 0.09 11.5 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase APH PF01636.23 PSC74773.1 - 1.9 8.4 6.6 0.61 10.0 2.5 2.4 2 1 0 2 2 2 0 Phosphotransferase enzyme family Ribosomal_S25 PF03297.15 PSC74776.1 - 2.5e-36 123.9 4.4 5.9e-36 122.7 4.4 1.7 1 0 0 1 1 1 1 S25 ribosomal protein SNF2_N PF00176.23 PSC74776.1 - 4.4e-23 81.6 0.0 8e-23 80.7 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC74776.1 - 2.3e-14 53.7 0.0 5.1e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Glyco_transf_8 PF01501.20 PSC74776.1 - 7.9e-06 25.6 0.0 6.3e-05 22.7 0.0 2.2 1 1 0 1 1 1 1 Glycosyl transferase family 8 HARP PF07443.13 PSC74776.1 - 8.2e-06 25.4 0.0 2.4e-05 23.9 0.0 1.8 1 0 0 1 1 1 1 HepA-related protein (HARP) ResIII PF04851.15 PSC74776.1 - 0.0007 19.6 0.0 0.018 15.1 0.0 2.8 2 2 1 3 3 3 1 Type III restriction enzyme, res subunit FAM220 PF15487.6 PSC74776.1 - 0.011 15.4 0.3 0.23 11.1 0.2 2.4 2 0 0 2 2 2 0 FAM220 family ERCC3_RAD25_C PF16203.5 PSC74776.1 - 0.05 12.8 0.0 0.09 12.0 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase eIF3_subunit PF08597.10 PSC74776.1 - 8.1 6.3 13.7 0.15 12.0 0.7 2.3 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit zf-C2H2_jaz PF12171.8 PSC74777.1 - 2.2e-09 37.4 0.8 2.9e-09 37.0 0.8 1.2 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 PSC74777.1 - 0.0087 16.4 0.2 0.0098 16.2 0.2 1.1 1 0 0 1 1 1 1 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 PSC74777.1 - 0.11 13.0 0.7 0.15 12.5 0.7 1.2 1 0 0 1 1 1 0 Zinc-finger of C2H2 type CLP_protease PF00574.23 PSC74778.1 - 3.7e-79 264.8 0.1 4.7e-79 264.5 0.1 1.1 1 0 0 1 1 1 1 Clp protease DUF3638 PF12340.8 PSC74779.1 - 7.8e-60 202.0 0.1 1.3e-59 201.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3638) DUF3645 PF12359.8 PSC74779.1 - 1.4e-08 34.0 0.0 3.2e-08 32.8 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3645) Atg14 PF10186.9 PSC74779.1 - 5.4 6.0 5.4 11 5.0 5.4 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HisG PF01634.18 PSC74780.1 - 1.7e-37 128.9 0.0 2.5e-37 128.3 0.0 1.2 1 0 0 1 1 1 1 ATP phosphoribosyltransferase HisG_C PF08029.11 PSC74780.1 - 8.8e-15 54.6 0.0 1.8e-14 53.6 0.0 1.6 1 0 0 1 1 1 1 HisG, C-terminal domain Polysacc_synt_2 PF02719.15 PSC74780.1 - 0.0011 18.1 0.0 0.0016 17.6 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DKCLD PF08068.12 PSC74781.1 - 6.1e-33 112.7 0.4 1.3e-30 105.3 0.3 2.6 2 0 0 2 2 2 1 DKCLD (NUC011) domain TruB_C_2 PF16198.5 PSC74781.1 - 1.7e-22 79.3 0.7 3.6e-22 78.3 0.7 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 PSC74781.1 - 2.1e-21 76.8 4.9 1e-19 71.3 0.5 3.5 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) PUA PF01472.20 PSC74781.1 - 5.6e-21 74.3 1.1 1.2e-20 73.2 1.1 1.6 1 0 0 1 1 1 1 PUA domain UPF0113 PF03657.13 PSC74781.1 - 0.0096 16.2 0.0 0.024 14.9 0.0 1.7 1 0 0 1 1 1 1 UPF0113 PUA domain DUF3682 PF12446.8 PSC74781.1 - 0.03 14.8 15.0 0.07 13.6 15.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) RNA_polI_A34 PF08208.11 PSC74781.1 - 0.28 11.3 23.4 0.44 10.6 23.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RR_TM4-6 PF06459.12 PSC74781.1 - 2.9 7.7 12.5 3.9 7.2 12.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Coilin_N PF15862.5 PSC74781.1 - 5.1 6.9 16.1 8.5 6.2 16.1 1.3 1 0 0 1 1 1 0 Coilin N-terminus DUF1840 PF08895.11 PSC74781.1 - 7.6 6.9 8.7 22 5.5 8.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Med19 PF10278.9 PSC74781.1 - 9 6.2 15.2 15 5.4 15.2 1.3 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 TFIIA PF03153.13 PSC74782.1 - 9.7 6.1 41.9 10 6.0 29.7 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit STI1 PF17830.1 PSC74784.1 - 8e-11 41.7 21.6 1.6e-10 40.8 1.3 4.6 4 1 0 4 4 4 3 STI1 domain RPN13_C PF16550.5 PSC74784.1 - 7.9e-06 26.0 1.9 8.2e-06 26.0 0.4 1.7 2 0 0 2 2 2 1 UCH-binding domain Ribosomal_S18 PF01084.20 PSC74785.1 - 4.9e-14 52.3 0.1 4.9e-14 52.3 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein S18 PDE6_gamma PF04868.12 PSC74785.1 - 0.14 12.4 0.0 0.14 12.4 0.0 2.2 3 0 0 3 3 3 0 Retinal cGMP phosphodiesterase, gamma subunit Rep_fac-A_C PF08646.10 PSC74786.1 - 7.3e-31 106.9 0.0 1.3e-30 106.1 0.0 1.4 1 0 0 1 1 1 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 PSC74786.1 - 3.6e-21 74.9 0.7 2.2e-17 62.8 0.2 3.6 4 0 0 4 4 4 2 Replication protein A OB domain Choline_kinase PF01633.20 PSC74786.1 - 5.4e-16 58.8 0.0 1e-15 57.9 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase tRNA_anti-codon PF01336.25 PSC74786.1 - 3.1e-12 46.3 2.8 0.00016 21.6 0.0 4.5 4 1 0 4 4 4 2 OB-fold nucleic acid binding domain Rep-A_N PF04057.12 PSC74786.1 - 0.074 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain Choline_kinase PF01633.20 PSC74787.1 - 4.1e-36 124.6 0.0 1e-17 64.5 0.0 2.4 1 1 1 2 2 2 2 Choline/ethanolamine kinase Rep_fac-A_C PF08646.10 PSC74787.1 - 7.8e-31 106.8 0.0 1.3e-30 106.0 0.0 1.3 1 0 0 1 1 1 1 Replication factor-A C terminal domain REPA_OB_2 PF16900.5 PSC74787.1 - 3.9e-21 74.8 0.7 2.2e-17 62.7 0.2 3.6 4 0 0 4 4 4 2 Replication protein A OB domain tRNA_anti-codon PF01336.25 PSC74787.1 - 2.7e-12 46.5 2.5 0.00017 21.5 0.0 4.6 4 0 0 4 4 4 2 OB-fold nucleic acid binding domain APH PF01636.23 PSC74787.1 - 5.3e-06 26.5 7.0 0.0076 16.2 0.4 3.2 3 1 0 3 3 3 2 Phosphotransferase enzyme family Rep-A_N PF04057.12 PSC74787.1 - 0.078 13.0 0.0 0.18 11.8 0.0 1.6 1 0 0 1 1 1 0 Replication factor-A protein 1, N-terminal domain DNA_pol_A_exo1 PF01612.20 PSC74788.1 - 1.3e-38 132.4 0.0 2.1e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease HRDC PF00570.23 PSC74788.1 - 8.5e-12 44.9 2.4 1.1e-11 44.6 0.2 2.4 2 0 0 2 2 2 1 HRDC domain PMC2NT PF08066.12 PSC74788.1 - 9.4e-06 26.2 0.0 0.0003 21.4 0.0 2.5 2 0 0 2 2 2 1 PMC2NT (NUC016) domain zf-MYND PF01753.18 PSC74788.1 - 0.0035 17.4 23.3 0.0081 16.2 23.3 1.7 1 0 0 1 1 1 1 MYND finger DUF3464 PF11947.8 PSC74788.1 - 0.17 11.6 0.7 0.58 9.9 0.7 1.8 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF2722 PF10846.8 PSC74788.1 - 2.7 6.8 11.5 1.1 8.2 6.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) AMP-binding PF00501.28 PSC74789.1 - 9.4e-62 209.0 2.1 3.6e-42 144.5 0.2 2.3 2 0 0 2 2 2 2 AMP-binding enzyme AMP-binding_C PF13193.6 PSC74789.1 - 2.5e-07 31.6 3.1 3.8e-07 31.0 0.6 2.4 2 1 1 3 3 3 1 AMP-binding enzyme C-terminal domain LRR_4 PF12799.7 PSC74790.1 - 3.6e-15 55.8 0.0 0.00039 20.8 0.0 3.7 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) Polysacc_deac_1 PF01522.21 PSC74790.1 - 5.1e-14 52.2 0.0 2.7e-13 49.9 0.0 2.0 2 0 0 2 2 2 1 Polysaccharide deacetylase LRR_8 PF13855.6 PSC74790.1 - 1.6e-13 50.2 4.3 0.00011 21.9 0.1 3.8 1 1 3 4 4 4 4 Leucine rich repeat LRR_1 PF00560.33 PSC74790.1 - 1.4e-07 31.1 0.0 6.7 7.7 0.0 6.3 6 0 0 6 6 6 1 Leucine Rich Repeat DUF3734 PF12536.8 PSC74790.1 - 0.19 12.1 0.0 0.34 11.3 0.0 1.3 1 0 0 1 1 1 0 Patatin phospholipase KH_6 PF15985.5 PSC74791.1 - 1.2e-07 32.0 0.5 2.4e-07 31.0 0.5 1.6 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 PSC74791.1 - 4.5e-06 26.4 0.3 1.4e-05 24.8 0.1 1.9 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region ketoacyl-synt PF00109.26 PSC74792.1 - 7.1e-49 166.7 1.4 1.7e-48 165.5 0.4 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain PP-binding PF00550.25 PSC74792.1 - 2.7e-30 104.5 1.2 4.1e-14 52.7 0.1 2.6 2 0 0 2 2 2 2 Phosphopantetheine attachment site Ketoacyl-synt_C PF02801.22 PSC74792.1 - 5.2e-30 103.9 0.9 5.2e-30 103.9 0.9 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 PSC74792.1 - 0.0036 17.7 0.0 0.0077 16.7 0.0 1.5 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_N PF08240.12 PSC74792.1 - 0.0092 15.9 0.0 0.026 14.4 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PLAC9 PF15205.6 PSC74792.1 - 0.012 16.0 0.5 7.1 7.1 0.0 3.0 3 0 0 3 3 3 0 Placenta-specific protein 9 PS-DH PF14765.6 PSC74792.1 - 0.014 14.7 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 Polyketide synthase dehydratase DEK_C PF08766.11 PSC74792.1 - 0.049 13.6 0.1 21 5.1 0.0 2.8 3 0 0 3 3 3 0 DEK C terminal domain PXT1 PF15214.6 PSC74792.1 - 0.16 12.4 0.1 11 6.5 0.0 2.5 2 0 0 2 2 2 0 Peroxisomal testis-specific protein 1 p31comet PF06581.12 PSC74793.1 - 0.0056 15.9 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 Mad1 and Cdc20-bound-Mad2 binding TT_ORF2 PF02957.15 PSC74793.1 - 0.24 12.3 0.7 0.82 10.6 0.7 2.0 1 0 0 1 1 1 0 TT viral ORF2 Tup_N PF08581.10 PSC74793.1 - 0.27 11.6 3.8 3.8 7.9 0.1 3.5 3 0 0 3 3 3 0 Tup N-terminal TPR_9 PF13371.6 PSC74794.1 - 3.7e-10 39.8 3.6 3.7e-10 39.8 3.6 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Transglut_core2 PF13369.6 PSC74794.1 - 5e-06 26.2 0.0 4.4e-05 23.1 0.0 2.3 1 1 0 1 1 1 1 Transglutaminase-like superfamily TPR_19 PF14559.6 PSC74794.1 - 0.036 14.6 3.1 0.038 14.5 0.6 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat PQ-loop PF04193.14 PSC74795.1 - 1e-07 31.6 0.2 1.5e-07 31.1 0.2 1.3 1 0 0 1 1 1 1 PQ loop repeat DUF4203 PF13886.6 PSC74795.1 - 0.048 13.3 3.9 0.076 12.7 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) tRNA-synt_2 PF00152.20 PSC74796.1 - 1.8e-104 349.2 0.0 2.2e-104 348.9 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 PSC74796.1 - 6.8e-17 61.5 0.1 1.2e-16 60.7 0.1 1.4 1 0 0 1 1 1 1 GAD domain tRNA_anti-codon PF01336.25 PSC74796.1 - 2.1e-16 59.6 0.0 3.8e-16 58.8 0.0 1.4 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 PSC74796.1 - 1.8e-06 27.6 0.1 0.0045 16.5 0.1 2.5 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) EF_assoc_2 PF08356.12 PSC74797.1 - 1.2e-28 98.9 0.0 2.4e-28 98.0 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_1 PF08355.12 PSC74797.1 - 1.7e-15 56.4 0.0 7.2e-15 54.3 0.0 2.0 2 0 0 2 2 2 1 EF hand associated Ras PF00071.22 PSC74797.1 - 9.8e-15 54.5 0.0 1.6e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PSC74797.1 - 6.5e-07 29.6 0.0 1.9e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase EF-hand_1 PF00036.32 PSC74797.1 - 3.6e-06 26.1 2.1 0.013 15.0 0.1 2.5 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 PSC74797.1 - 9.3e-06 25.2 2.2 0.073 13.0 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 PSC74797.1 - 1.1e-05 25.7 0.2 0.21 12.1 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 PSC74797.1 - 0.00054 19.3 1.7 0.3 10.7 0.1 2.6 2 0 0 2 2 2 2 EF hand AAA_16 PF13191.6 PSC74797.1 - 0.011 16.1 0.1 0.11 12.9 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 PSC74797.1 - 0.026 14.8 0.0 0.61 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain EF-hand_8 PF13833.6 PSC74797.1 - 0.13 12.1 0.2 8.1 6.4 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain pair SRCR PF00530.18 PSC74798.1 - 1e-35 122.3 4.1 1.9e-13 50.7 0.0 4.4 4 1 0 4 4 4 3 Scavenger receptor cysteine-rich domain SRCR PF00530.18 PSC74799.1 - 1e-35 122.2 4.1 1.8e-13 50.8 0.0 4.4 4 1 0 4 4 4 3 Scavenger receptor cysteine-rich domain NAPRTase_N PF17767.1 PSC74800.1 - 0.13 12.6 0.0 0.56 10.6 0.0 2.0 1 1 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase_N PF17767.1 PSC74801.1 - 0.095 13.1 0.0 0.96 9.8 0.0 2.1 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain Ribonuclease_T2 PF00445.18 PSC74802.1 - 7.5e-33 114.3 0.1 9.7e-33 113.9 0.1 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family DUF1442 PF07279.11 PSC74803.1 - 0.028 13.7 0.0 0.058 12.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) PUF PF00806.19 PSC74804.1 - 4.3e-54 177.3 0.0 4e-06 26.2 0.0 8.4 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Sulfotransfer_2 PF03567.14 PSC74804.1 - 1.2e-06 28.6 0.0 3.8e-06 27.0 0.1 1.7 1 1 0 1 1 1 1 Sulfotransferase family CPL PF08144.11 PSC74804.1 - 0.24 11.7 0.1 5.9 7.2 0.0 2.5 1 1 1 2 2 2 0 CPL (NUC119) domain Amidase PF01425.21 PSC74805.1 - 3.5e-65 220.7 4.1 5.2e-64 216.9 4.1 2.0 1 1 0 1 1 1 1 Amidase YCII PF03795.14 PSC74805.1 - 5.9e-07 29.8 0.0 2.3e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 YCII-related domain PP-binding PF00550.25 PSC74806.1 - 3.4e-06 27.3 0.0 5.9e-06 26.5 0.0 1.4 1 1 0 1 1 1 1 Phosphopantetheine attachment site CLU PF13236.6 PSC74806.1 - 0.22 11.3 0.0 0.26 11.1 0.0 1.1 1 0 0 1 1 1 0 Clustered mitochondria Pyridoxal_deC PF00282.19 PSC74807.1 - 1.8e-52 178.3 0.0 6.3e-31 107.4 0.0 2.3 2 0 0 2 2 2 2 Pyridoxal-dependent decarboxylase conserved domain HK PF02110.15 PSC74808.1 - 1.3e-74 250.7 0.7 1.5e-74 250.5 0.7 1.0 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.17 PSC74808.1 - 0.002 17.7 0.5 0.0033 17.0 0.4 1.3 1 1 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 PSC74809.1 - 1.3e-74 250.7 0.7 1.5e-74 250.5 0.7 1.0 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Carb_kinase PF01256.17 PSC74809.1 - 0.002 17.7 0.5 0.0033 17.0 0.4 1.3 1 1 0 1 1 1 1 Carbohydrate kinase zf-CCCH_4 PF18044.1 PSC74810.1 - 9.6e-05 22.1 1.2 9.6e-05 22.1 1.2 3.6 3 0 0 3 3 3 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PSC74810.1 - 0.00016 21.6 3.1 0.00016 21.6 3.1 3.4 3 1 1 4 4 4 2 Zinc finger domain zf-RanBP PF00641.18 PSC74810.1 - 0.00017 20.8 2.6 0.00017 20.8 2.6 2.0 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-CCCH PF00642.24 PSC74810.1 - 0.037 14.0 3.2 0.037 14.0 3.2 2.6 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Glyco_trans_4_4 PF13579.6 PSC74811.1 - 0.0048 17.4 3.8 0.0048 17.4 3.8 2.3 1 1 1 2 2 2 1 Glycosyl transferase 4-like domain CoA_trans PF01144.23 PSC74812.1 - 2.3e-32 112.1 0.4 1.1e-31 109.9 0.0 2.1 3 0 0 3 3 3 1 Coenzyme A transferase Mal_decarbox_Al PF16957.5 PSC74812.1 - 0.0028 16.1 0.0 0.0046 15.4 0.0 1.2 1 0 0 1 1 1 1 Malonate decarboxylase, alpha subunit, transporter ArsA_ATPase PF02374.15 PSC74813.1 - 4.2e-105 351.3 0.0 6e-105 350.8 0.0 1.2 1 0 0 1 1 1 1 Anion-transporting ATPase AAA_31 PF13614.6 PSC74813.1 - 1.9e-10 40.9 0.1 1.5e-09 38.0 0.0 2.4 2 1 0 2 2 2 1 AAA domain CbiA PF01656.23 PSC74813.1 - 2.5e-10 40.5 0.0 4.2e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain CBP_BcsQ PF06564.12 PSC74813.1 - 1.7e-05 24.4 0.0 4.7e-05 23.0 0.0 1.6 2 0 0 2 2 2 1 Cellulose biosynthesis protein BcsQ ParA PF10609.9 PSC74813.1 - 3e-05 23.6 0.3 0.00032 20.2 0.1 2.2 2 0 0 2 2 2 1 NUBPL iron-transfer P-loop NTPase Fer4_NifH PF00142.18 PSC74813.1 - 0.00012 21.7 0.0 0.00023 20.7 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 PSC74813.1 - 0.0037 16.9 0.2 0.032 13.9 0.0 2.4 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 PSC74813.1 - 0.012 14.9 0.0 0.024 13.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.6 PSC74813.1 - 0.013 15.1 0.1 0.044 13.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PSC74813.1 - 0.034 14.5 0.1 0.49 10.7 0.0 2.3 2 1 0 2 2 2 0 AAA ATPase domain NB-ARC PF00931.22 PSC74813.1 - 0.066 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Rootletin PF15035.6 PSC74813.1 - 0.14 12.2 1.3 0.9 9.5 0.4 2.1 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion Clathrin PF00637.20 PSC74814.1 - 9.6e-16 57.9 0.0 2.8e-15 56.5 0.0 1.7 2 0 0 2 2 2 1 Region in Clathrin and VPS ANAPC4_WD40 PF12894.7 PSC74814.1 - 0.00012 22.3 0.0 0.0027 18.0 0.0 2.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PSC74814.1 - 0.00022 22.0 0.0 0.0017 19.1 0.0 2.5 2 0 0 2 2 2 1 WD domain, G-beta repeat TPR_10 PF13374.6 PSC74814.1 - 0.05 13.5 2.6 8.4 6.4 0.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF647 PF04884.14 PSC74815.1 - 2.2e-38 132.3 4.9 3.1e-38 131.8 4.9 1.2 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis 2-Hacid_dh_C PF02826.19 PSC74816.1 - 5.5e-62 208.3 0.0 1.2e-61 207.2 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 PSC74816.1 - 9.7e-35 119.2 1.1 1.6e-34 118.4 0.3 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain ACT PF01842.25 PSC74816.1 - 1.9e-08 33.9 0.3 6.3e-08 32.3 0.3 2.0 1 0 0 1 1 1 1 ACT domain AdoHcyase_NAD PF00670.21 PSC74816.1 - 3.5e-05 23.9 0.1 8.7e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain IlvN PF07991.12 PSC74816.1 - 6.6e-05 22.5 0.1 0.00019 21.0 0.0 1.9 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain ACT_7 PF13840.6 PSC74816.1 - 0.00092 19.0 0.3 0.0041 16.9 0.1 2.2 2 0 0 2 2 2 1 ACT domain NAD_binding_2 PF03446.15 PSC74816.1 - 0.011 15.8 1.3 0.057 13.6 0.1 2.7 3 0 0 3 3 3 0 NAD binding domain of 6-phosphogluconate dehydrogenase XdhC_C PF13478.6 PSC74816.1 - 0.016 15.7 0.3 0.051 14.1 0.0 2.0 2 0 0 2 2 2 0 XdhC Rossmann domain TrkA_N PF02254.18 PSC74816.1 - 0.025 14.8 0.5 0.2 11.9 0.0 2.8 3 0 0 3 3 3 0 TrkA-N domain ACT_4 PF13291.6 PSC74816.1 - 0.076 13.6 2.4 0.13 12.8 0.4 2.3 2 0 0 2 2 2 0 ACT domain F420_oxidored PF03807.17 PSC74816.1 - 0.089 13.4 2.0 1.1 9.9 0.0 3.2 3 0 0 3 3 3 0 NADP oxidoreductase coenzyme F420-dependent Aldose_epim PF01263.20 PSC74817.1 - 2.7e-79 266.6 0.0 3.5e-79 266.2 0.0 1.1 1 0 0 1 1 1 1 Aldose 1-epimerase DUF2269 PF10027.9 PSC74817.1 - 0.011 15.8 0.3 0.019 15.0 0.3 1.4 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2269) KDZ PF18758.1 PSC74817.1 - 0.051 13.2 0.3 0.08 12.5 0.3 1.2 1 0 0 1 1 1 0 Kyakuja-Dileera-Zisupton transposase Megourin PF17560.2 PSC74817.1 - 0.11 12.8 0.2 29 5.0 0.4 2.5 2 0 0 2 2 2 0 Aphid Megourins Aldo_ket_red PF00248.21 PSC74818.1 - 6e-38 130.7 0.0 3e-36 125.1 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family NinG PF05766.12 PSC74819.1 - 0.039 13.9 0.1 0.04 13.8 0.1 1.1 1 0 0 1 1 1 0 Bacteriophage Lambda NinG protein Ribosomal_S16 PF00886.19 PSC74820.1 - 4e-26 90.8 0.0 5.3e-26 90.5 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S16 RRM_1 PF00076.22 PSC74821.1 - 9.1e-09 35.0 0.0 1.8e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PSC74821.1 - 0.0022 17.9 0.0 0.0045 17.0 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif TFIIA PF03153.13 PSC74821.1 - 0.0023 18.0 6.8 0.0023 18.0 6.8 2.6 2 1 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit DUF2722 PF10846.8 PSC74821.1 - 0.0052 15.8 5.0 0.0052 15.8 5.0 3.9 2 1 2 4 4 4 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 PSC74821.1 - 0.0094 15.6 12.7 0.0094 15.6 12.7 2.9 2 1 0 2 2 2 1 Spt20 family Glyco_hydro_52 PF03512.13 PSC74821.1 - 0.13 11.2 1.0 0.24 10.3 1.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 52 Endostatin PF06482.11 PSC74821.1 - 7.1 6.0 16.1 16 4.8 0.2 2.4 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin Thioesterase PF00975.20 PSC74822.1 - 3.5e-08 33.8 0.0 7.6e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Thioesterase domain Hydrolase_4 PF12146.8 PSC74822.1 - 0.00095 18.5 0.8 0.0051 16.1 0.1 2.4 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PSC74822.1 - 0.045 13.4 0.0 0.087 12.5 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Lactococcin_972 PF09683.10 PSC74822.1 - 1.3 9.6 5.6 4.5 7.9 5.6 1.9 1 0 0 1 1 1 0 Bacteriocin (Lactococcin_972) ABC_ATPase PF09818.9 PSC74823.1 - 4.2e-175 582.9 0.0 5e-175 582.6 0.0 1.1 1 0 0 1 1 1 1 Predicted ATPase of the ABC class AAA_23 PF13476.6 PSC74823.1 - 0.00073 20.1 0.0 0.0012 19.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 PSC74823.1 - 0.065 12.8 0.1 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain SOAR PF16533.5 PSC74824.1 - 0.045 13.7 6.7 0.091 12.7 6.7 1.6 1 0 0 1 1 1 0 STIM1 Orai1-activating region MAJIN PF15077.6 PSC74824.1 - 0.24 11.1 1.1 0.43 10.3 1.1 1.4 1 0 0 1 1 1 0 Membrane-anchored junction protein Jnk-SapK_ap_N PF09744.9 PSC74824.1 - 1.9 8.7 14.1 0.7 10.1 11.3 1.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 SOAR PF16533.5 PSC74825.1 - 0.048 13.6 6.7 0.098 12.6 6.7 1.6 1 0 0 1 1 1 0 STIM1 Orai1-activating region DUF29 PF01724.16 PSC74825.1 - 0.63 10.3 7.2 11 6.2 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function DUF29 Jnk-SapK_ap_N PF09744.9 PSC74825.1 - 4.4 7.5 17.0 0.92 9.7 11.7 2.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 PIN_8 PF18476.1 PSC74825.1 - 7.5 6.3 6.7 4.4 7.1 4.2 1.7 1 1 1 2 2 2 0 PIN like domain rve PF00665.26 PSC74826.1 - 8.3e-19 67.9 0.0 1.8e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC74826.1 - 0.0065 16.2 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Nop PF01798.18 PSC74827.1 - 8.2e-89 297.0 0.1 1.2e-88 296.4 0.1 1.3 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 PSC74827.1 - 1.6e-19 70.1 1.3 1.6e-19 70.1 1.3 2.3 2 0 0 2 2 2 1 NOP5NT (NUC127) domain ApoC-I PF04691.12 PSC74827.1 - 0.032 14.1 4.2 0.079 12.9 0.1 3.1 3 0 0 3 3 3 0 Apolipoprotein C-I (ApoC-1) RNA_polI_A34 PF08208.11 PSC74827.1 - 0.41 10.7 16.2 0.71 9.9 16.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 E1_dh PF00676.20 PSC74828.1 - 1.1e-109 366.0 0.2 1.4e-109 365.7 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 PSC74828.1 - 0.0058 15.9 1.0 0.0083 15.4 0.2 1.6 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Chromate_transp PF02417.15 PSC74829.1 - 3.5e-56 189.7 33.2 4.7e-32 111.3 11.3 3.0 2 0 0 2 2 2 2 Chromate transporter Castor_Poll_mid PF06241.12 PSC74829.1 - 3.5e-10 39.8 0.0 5.1e-07 29.6 0.0 2.7 2 0 0 2 2 2 2 Castor and Pollux, part of voltage-gated ion channel Ion_trans_2 PF07885.16 PSC74829.1 - 0.0076 16.2 1.0 2.4 8.2 0.1 2.8 2 0 0 2 2 2 2 Ion channel Melibiase_2_C PF17450.2 PSC74829.1 - 0.18 12.0 0.0 13 6.1 0.0 2.6 2 0 0 2 2 2 0 Alpha galactosidase A C-terminal beta sandwich domain T3SS_ExsE PF18286.1 PSC74829.1 - 0.28 11.2 2.2 12 6.0 0.2 3.1 3 0 0 3 3 3 0 Type III secretion system ExsE CCB1 PF12046.8 PSC74829.1 - 0.89 8.9 5.1 5.7 6.2 0.3 2.6 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B Oxidored_q2 PF00420.24 PSC74829.1 - 1.4 8.6 3.8 24 4.6 0.4 3.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF2871 PF11070.8 PSC74829.1 - 2.6 8.3 6.0 14 6.0 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2871) Trm112p PF03966.16 PSC74830.1 - 1.6e-16 60.6 0.0 1.9e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Trm112p-like protein FF PF01846.19 PSC74832.1 - 1.5e-53 178.8 3.0 4.1e-10 39.7 0.0 5.7 5 0 0 5 5 5 5 FF domain WW PF00397.26 PSC74832.1 - 2.9e-17 62.5 19.3 3.2e-09 36.7 4.6 3.2 3 0 0 3 3 3 2 WW domain Ephrin_rec_like PF07699.13 PSC74833.1 - 5.4e-52 173.3 197.7 1.4e-09 37.6 5.0 18.9 7 5 12 19 19 19 16 Putative ephrin-receptor like NCD3G PF07562.14 PSC74833.1 - 1.8e-16 59.8 131.2 0.016 15.2 6.3 17.3 7 5 9 19 19 19 17 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 PSC74833.1 - 0.0034 17.8 123.5 0.61 10.5 3.7 20.8 10 8 10 22 22 22 11 TNFR/NGFR cysteine-rich region SATase_N PF06426.14 PSC74834.1 - 3.1e-34 117.5 0.4 4.1e-34 117.1 0.4 1.2 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 PSC74834.1 - 1.1e-10 40.8 5.6 2.5e-06 27.0 0.2 2.6 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 PSC74834.1 - 0.00029 20.5 5.2 0.014 15.2 0.2 2.4 2 0 0 2 2 2 2 Hexapeptide repeat of succinyl-transferase eIF-5_eIF-2B PF01873.17 PSC74835.1 - 3.9e-30 104.1 0.1 8.7e-30 103.0 0.1 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.18 PSC74835.1 - 2.6e-12 46.7 0.4 2.6e-12 46.7 0.4 3.8 2 1 1 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Sigma70_ner PF04546.13 PSC74835.1 - 9.9e-08 32.1 3.1 2.6e-05 24.2 0.1 3.7 2 1 0 2 2 2 1 Sigma-70, non-essential region Nop14 PF04147.12 PSC74835.1 - 0.0049 15.2 28.4 0.0067 14.7 28.4 1.2 1 0 0 1 1 1 1 Nop14-like family Elf1 PF05129.13 PSC74835.1 - 0.027 14.5 0.4 0.027 14.5 0.4 2.2 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like Neur_chan_memb PF02932.16 PSC74835.1 - 2.3 8.2 10.2 4.1 7.4 10.2 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region BAF1_ABF1 PF04684.13 PSC74835.1 - 4.4 6.2 17.9 5.8 5.9 17.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF155 PF02582.14 PSC74837.1 - 1.9e-46 158.4 0.1 2.6e-46 157.9 0.1 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Zeta_toxin PF06414.12 PSC74837.1 - 0.0061 15.9 0.0 0.014 14.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin DUF2309 PF10070.9 PSC74837.1 - 0.22 9.8 0.0 0.28 9.5 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2309) Glyco_hydro_125 PF06824.11 PSC74838.1 - 1.7e-95 320.4 0.0 2.2e-95 320.0 0.0 1.1 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) S-methyl_trans PF02574.16 PSC74839.1 - 6.2e-37 127.9 0.0 6.9e-37 127.7 0.0 1.0 1 0 0 1 1 1 1 Homocysteine S-methyltransferase DUF525 PF04379.14 PSC74841.1 - 1.9e-21 76.1 0.0 4.3e-21 74.9 0.0 1.6 1 0 0 1 1 1 1 ApaG domain TolA_bind_tri PF16331.5 PSC74842.1 - 0.00027 20.9 7.5 0.00027 20.9 7.5 5.5 6 2 1 7 7 7 1 TolA binding protein trimerisation JIP_LZII PF16471.5 PSC74842.1 - 0.00092 19.3 0.2 0.00092 19.3 0.2 4.5 5 0 0 5 5 5 1 JNK-interacting protein leucine zipper II HALZ PF02183.18 PSC74842.1 - 0.2 11.9 12.8 2.4 8.5 0.5 5.0 4 0 0 4 4 4 0 Homeobox associated leucine zipper HMMR_C PF15908.5 PSC74842.1 - 0.68 10.2 14.0 0.093 13.0 8.4 2.5 2 1 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal Ctf8 PF09696.10 PSC74842.1 - 2.5 8.4 7.5 1.5 9.2 2.8 2.5 1 1 0 2 2 2 0 Ctf8 Spc7 PF08317.11 PSC74842.1 - 5 5.9 49.1 0.12 11.2 17.2 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein Fungal_TACC PF12709.7 PSC74842.1 - 5.7 7.5 7.5 15 6.1 0.3 3.6 3 1 1 4 4 4 0 Fungal Transforming acidic coiled-coil (TACC) proteins RNA_pol PF00940.19 PSC74843.1 - 7.1e-150 499.4 0.0 1.9e-137 458.5 0.0 2.7 1 1 0 2 2 2 2 DNA-dependent RNA polymerase RPOL_N PF14700.6 PSC74843.1 - 1.3e-62 212.1 0.6 1.8e-62 211.7 0.6 1.2 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal LRR_4 PF12799.7 PSC74844.1 - 3.3e-05 24.2 2.5 9.8 6.8 0.0 7.6 8 3 1 9 9 9 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PSC74844.1 - 7.5e-05 22.5 8.4 2.5 8.4 0.0 6.7 7 0 0 7 7 7 2 Leucine Rich repeat F-box PF00646.33 PSC74844.1 - 3.7 7.6 5.6 0.47 10.4 0.1 2.5 3 0 0 3 3 3 0 F-box domain Pkinase PF00069.25 PSC74845.1 - 1.6e-70 237.5 0.0 2.5e-70 236.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74845.1 - 1.9e-50 171.6 0.0 3.1e-50 170.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase rve PF00665.26 PSC74845.1 - 9.2e-18 64.6 0.0 2.4e-17 63.2 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain VPS13_C PF16909.5 PSC74845.1 - 2.2e-15 56.9 0.1 2.2e-15 56.9 0.1 2.2 2 0 0 2 2 2 1 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 PSC74845.1 - 1.6e-09 37.9 0.2 9.8e-09 35.3 0.0 2.5 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 Pkinase_fungal PF17667.1 PSC74845.1 - 0.0039 16.0 0.0 0.01 14.7 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase ATG_C PF09333.11 PSC74845.1 - 0.0096 16.3 0.2 0.0096 16.3 0.2 2.9 2 0 0 2 2 1 1 Autophagy-related protein C terminal domain Kinase-like PF14531.6 PSC74845.1 - 0.026 13.8 0.2 0.074 12.4 0.2 1.7 1 1 0 1 1 1 0 Kinase-like rve_3 PF13683.6 PSC74845.1 - 0.067 13.0 0.0 0.2 11.5 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain VPS13 PF16908.5 PSC74845.1 - 0.14 12.0 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 Vacuolar sorting-associated protein 13, N-terminal Arm PF00514.23 PSC74845.1 - 0.78 9.9 9.9 0.29 11.3 0.2 5.1 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat LRR_8 PF13855.6 PSC74846.1 - 0.013 15.2 4.9 0.036 13.8 0.7 3.1 3 0 0 3 3 3 0 Leucine rich repeat LRR_4 PF12799.7 PSC74846.1 - 0.66 10.5 2.5 49 4.5 0.0 4.1 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Trypsin_2 PF13365.6 PSC74848.1 - 2e-31 109.9 2.7 2e-31 109.9 2.7 1.6 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 PSC74848.1 - 2.8e-16 60.0 0.1 4.2e-16 59.4 0.1 1.2 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 PSC74848.1 - 8.3e-09 35.2 0.1 2.7e-08 33.5 0.1 1.9 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PSC74848.1 - 4.7e-06 26.8 0.0 1.9e-05 24.9 0.0 2.0 2 0 0 2 2 2 1 PDZ domain Peptidase_S46 PF10459.9 PSC74848.1 - 4.4e-05 22.4 1.1 0.025 13.3 0.1 2.2 2 0 0 2 2 2 2 Peptidase S46 PDZ PF00595.24 PSC74848.1 - 5.6e-05 23.4 0.0 0.00014 22.2 0.0 1.7 1 0 0 1 1 1 1 PDZ domain LSM PF01423.22 PSC74848.1 - 0.0068 16.1 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 LSM domain Nucleic_acid_bd PF13820.6 PSC74848.1 - 0.17 11.7 0.0 0.4 10.5 0.0 1.6 1 0 0 1 1 1 0 Putative nucleic acid-binding region Trypsin_2 PF13365.6 PSC74849.1 - 9.8e-32 110.9 2.7 2e-31 109.9 2.7 1.5 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 PSC74849.1 - 2.7e-16 60.1 0.1 4.2e-16 59.4 0.1 1.3 1 0 0 1 1 1 1 Trypsin PDZ_6 PF17820.1 PSC74849.1 - 5.5e-10 38.9 0.1 2e-09 37.1 0.1 2.1 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PSC74849.1 - 5.6e-08 33.0 0.1 2.2e-07 31.1 0.0 2.0 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 PSC74849.1 - 3.7e-05 24.0 0.0 9.2e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 PDZ domain Peptidase_S46 PF10459.9 PSC74849.1 - 4.4e-05 22.4 1.1 0.025 13.3 0.1 2.2 2 0 0 2 2 2 2 Peptidase S46 LSM PF01423.22 PSC74849.1 - 0.0065 16.1 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 LSM domain GRASP55_65 PF04495.14 PSC74849.1 - 0.036 14.4 0.0 0.11 12.9 0.0 1.7 1 0 0 1 1 1 0 GRASP55/65 PDZ-like domain Nucleic_acid_bd PF13820.6 PSC74849.1 - 0.19 11.6 0.0 0.44 10.4 0.0 1.6 1 0 0 1 1 1 0 Putative nucleic acid-binding region Glyco_transf_7N PF13733.6 PSC74850.1 - 4.4e-22 78.2 0.0 7.1e-22 77.5 0.0 1.3 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_transf_7C PF02709.14 PSC74850.1 - 8.5e-16 57.4 0.0 1.6e-15 56.5 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Peptidase_M50 PF02163.22 PSC74852.1 - 3.7e-12 46.1 7.6 4.7e-06 26.1 0.1 2.8 1 1 0 2 2 2 2 Peptidase family M50 DUF1173 PF06666.11 PSC74852.1 - 0.025 13.5 0.0 0.036 13.0 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1173) Tim44 PF04280.15 PSC74853.1 - 9.2e-37 126.4 0.0 1.8e-36 125.4 0.0 1.5 1 0 0 1 1 1 1 Tim44-like domain MRP-S31 PF15433.6 PSC74853.1 - 0.089 12.5 9.8 0.033 13.9 6.9 1.7 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S31 YtxH PF12732.7 PSC74853.1 - 0.16 12.5 11.3 52 4.5 10.9 3.7 2 1 0 2 2 2 0 YtxH-like protein TFIIA PF03153.13 PSC74853.1 - 0.66 9.9 19.9 0.85 9.6 19.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Malate_synthase PF01274.22 PSC74854.1 - 4.1e-208 691.9 0.0 4.7e-208 691.7 0.0 1.0 1 0 0 1 1 1 1 Malate synthase ICL PF00463.21 PSC74855.1 - 3.3e-107 359.2 0.6 4.5e-53 180.5 0.0 2.1 1 1 1 2 2 2 2 Isocitrate lyase family Mito_carr PF00153.27 PSC74855.1 - 1.4e-55 185.2 1.1 3.9e-20 71.6 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein PEP_mutase PF13714.6 PSC74855.1 - 7.3e-18 64.9 0.0 1.4e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase Rubredoxin PF00301.20 PSC74856.1 - 1.2e-18 66.9 4.4 1.8e-18 66.3 4.4 1.3 1 0 0 1 1 1 1 Rubredoxin Elf1 PF05129.13 PSC74856.1 - 0.015 15.3 0.7 1 9.4 0.0 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like HypA PF01155.19 PSC74856.1 - 0.027 14.5 0.2 0.039 14.0 0.2 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TF_Zn_Ribbon PF08271.12 PSC74856.1 - 0.028 13.9 1.3 3.2 7.4 0.2 2.2 2 0 0 2 2 2 0 TFIIB zinc-binding DUF2072 PF09845.9 PSC74856.1 - 0.13 12.5 0.2 0.58 10.4 0.0 1.9 2 0 0 2 2 2 0 Zn-ribbon containing protein zf-C2H2_3 PF13878.6 PSC74856.1 - 0.24 11.3 1.0 5.4 6.9 0.1 2.3 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-RanBP PF00641.18 PSC74856.1 - 0.3 10.5 0.3 0.3 10.5 0.3 1.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others Zn_ribbon_SprT PF17283.2 PSC74856.1 - 0.31 11.0 2.2 3.2 7.7 0.1 2.4 2 0 0 2 2 2 0 SprT-like zinc ribbon domain TFIIS_C PF01096.18 PSC74856.1 - 2.3 8.2 6.3 0.95 9.4 0.3 2.8 3 0 0 3 3 3 0 Transcription factor S-II (TFIIS) Rubredoxin_2 PF18073.1 PSC74856.1 - 2.4 7.9 7.6 2.4 8.0 0.4 2.7 3 0 0 3 3 3 0 Rubredoxin metal binding domain LysM PF01476.20 PSC74857.1 - 9.1e-42 140.9 0.0 1.5e-10 40.9 0.0 4.6 4 0 0 4 4 4 4 LysM domain Fasciclin PF02469.22 PSC74857.1 - 2.4e-41 140.9 2.4 1.5e-23 83.4 0.9 2.3 2 0 0 2 2 2 2 Fasciclin domain RVT_1 PF00078.27 PSC74858.1 - 6.4e-34 117.4 0.0 1e-33 116.8 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Exo_endo_phos PF03372.23 PSC74858.1 - 2.3e-07 30.6 0.4 7.7e-07 28.9 0.4 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family IGF2_C PF08365.11 PSC74858.1 - 0.57 10.2 7.6 12 6.0 0.4 3.6 4 0 0 4 4 4 0 Insulin-like growth factor II E-peptide Aha1_N PF09229.11 PSC74859.1 - 1.6e-23 83.4 0.0 1.9e-23 83.2 0.0 1.1 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal TraB PF01963.17 PSC74860.1 - 8.7e-25 88.1 0.1 2.1e-24 86.9 0.1 1.5 1 1 0 1 1 1 1 TraB family VASP_tetra PF08776.11 PSC74860.1 - 2.6 7.7 6.9 1 9.0 4.1 1.8 2 1 0 2 2 2 0 VASP tetramerisation domain ATG16 PF08614.11 PSC74863.1 - 0.0074 16.5 4.8 0.0074 16.5 4.8 4.0 3 1 2 5 5 4 2 Autophagy protein 16 (ATG16) GAS PF13851.6 PSC74863.1 - 0.013 14.8 8.0 0.036 13.4 0.4 2.5 2 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Spc7 PF08317.11 PSC74863.1 - 0.013 14.4 11.7 0.057 12.3 1.2 2.2 2 0 0 2 2 2 0 Spc7 kinetochore protein ADIP PF11559.8 PSC74863.1 - 0.019 15.1 1.1 0.019 15.1 1.1 2.8 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding DUF724 PF05266.14 PSC74863.1 - 0.058 13.2 4.1 0.088 12.6 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) API5 PF05918.11 PSC74863.1 - 0.12 11.1 0.4 0.26 10.0 0.4 1.4 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) NPV_P10 PF05531.12 PSC74863.1 - 0.19 12.2 3.4 10 6.6 0.2 2.8 3 0 0 3 3 3 0 Nucleopolyhedrovirus P10 protein AAA_13 PF13166.6 PSC74863.1 - 0.28 9.8 4.0 0.42 9.2 4.0 1.2 1 0 0 1 1 1 0 AAA domain Wtap PF17098.5 PSC74863.1 - 0.62 10.0 13.5 3.7 7.5 9.6 3.0 1 1 1 2 2 2 0 WTAP/Mum2p family APG6_N PF17675.1 PSC74863.1 - 0.68 10.5 18.9 0.094 13.2 1.2 2.7 2 1 0 2 2 2 0 Apg6 coiled-coil region Fez1 PF06818.15 PSC74863.1 - 0.71 10.3 10.4 0.36 11.3 3.6 2.3 1 1 0 1 1 1 0 Fez1 Golgin_A5 PF09787.9 PSC74863.1 - 0.72 9.3 8.5 0.67 9.4 5.7 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 5 DHR10 PF18595.1 PSC74863.1 - 0.76 9.8 28.3 0.56 10.3 12.0 2.5 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain Leu_zip PF15294.6 PSC74863.1 - 0.98 8.9 4.4 1.4 8.3 1.4 2.0 2 0 0 2 2 2 0 Leucine zipper UPF0242 PF06785.11 PSC74863.1 - 1 9.4 3.6 20 5.2 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HAP1_N PF04849.13 PSC74863.1 - 1.1 8.4 10.6 1.2 8.2 1.3 2.3 2 0 0 2 2 2 0 HAP1 N-terminal conserved region DUF641 PF04859.12 PSC74863.1 - 1.5 9.2 7.5 1.7 9.0 0.3 2.6 2 1 0 2 2 2 0 Plant protein of unknown function (DUF641) CENP-F_leu_zip PF10473.9 PSC74863.1 - 2 8.5 8.7 1.2 9.1 0.2 2.4 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Phage_GP20 PF06810.11 PSC74863.1 - 2.1 8.2 9.3 2.9 7.7 1.9 2.7 1 1 0 2 2 2 0 Phage minor structural protein GP20 MAD PF05557.13 PSC74863.1 - 2.1 6.6 6.9 2.6 6.3 5.8 1.6 1 1 0 1 1 1 0 Mitotic checkpoint protein Macoilin PF09726.9 PSC74863.1 - 3.9 5.9 8.0 16 3.9 8.0 1.8 1 1 0 1 1 1 0 Macoilin family Jnk-SapK_ap_N PF09744.9 PSC74863.1 - 4.4 7.5 10.3 13 6.0 3.1 2.5 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 BRE1 PF08647.11 PSC74863.1 - 4.6 7.4 9.2 0.21 11.7 0.7 2.6 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase Lebercilin PF15619.6 PSC74863.1 - 5.9 6.5 11.7 0.26 10.9 1.3 2.4 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Filament PF00038.21 PSC74863.1 - 6.8 6.2 16.8 3.8 7.0 3.3 2.3 1 1 1 2 2 2 0 Intermediate filament protein ERM PF00769.19 PSC74863.1 - 6.9 6.4 23.6 18 5.1 23.5 1.7 1 1 0 1 1 1 0 Ezrin/radixin/moesin family BST2 PF16716.5 PSC74863.1 - 9.2 6.9 15.9 1 10.0 1.1 3.3 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 WD40 PF00400.32 PSC74864.1 - 1.3e-09 38.5 7.2 0.011 16.6 0.0 5.8 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC74864.1 - 3.8e-05 23.9 0.0 1.2 9.5 0.0 3.6 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PSC74864.1 - 0.0012 17.9 0.2 0.042 12.8 0.0 2.7 2 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 PSC74864.1 - 0.062 13.3 0.0 6.3 6.9 0.0 3.0 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat zf-CSL PF05207.13 PSC74865.1 - 7.8e-12 44.7 0.1 1.2e-11 44.1 0.1 1.3 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 PSC74865.1 - 0.00051 20.1 0.0 0.00087 19.4 0.0 1.4 1 0 0 1 1 1 1 DnaJ domain DUF3035 PF11233.8 PSC74865.1 - 0.05 13.9 1.0 0.08 13.2 1.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3035) CMAS PF02353.20 PSC74866.1 - 1.3e-79 267.3 0.0 2.2e-79 266.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Amino_oxidase PF01593.24 PSC74866.1 - 3.7e-22 79.2 2.0 8.7e-20 71.4 2.0 2.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase Methyltransf_25 PF13649.6 PSC74866.1 - 6.1e-16 58.9 0.0 2.8e-15 56.8 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_8 PF13450.6 PSC74866.1 - 1.1e-15 57.6 0.1 1.1e-15 57.6 0.1 2.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Methyltransf_11 PF08241.12 PSC74866.1 - 2.9e-13 50.3 0.0 1.6e-11 44.7 0.0 2.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC74866.1 - 3.3e-11 43.8 0.0 8e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC74866.1 - 3.4e-10 39.9 0.0 6.9e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC74866.1 - 1.1e-09 38.4 0.0 2.1e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain FAD_binding_2 PF00890.24 PSC74866.1 - 8.2e-07 28.4 0.9 1.3e-05 24.5 0.3 2.8 3 0 0 3 3 3 1 FAD binding domain Pyr_redox_2 PF07992.14 PSC74866.1 - 1.2e-06 28.0 0.1 9.5e-06 25.0 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PSC74866.1 - 1.7e-06 27.8 0.5 5.7e-06 26.2 0.5 1.9 1 0 0 1 1 1 1 FAD dependent oxidoreductase NodS PF05401.11 PSC74866.1 - 5.9e-05 22.8 0.0 9.6e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) FAD_oxidored PF12831.7 PSC74866.1 - 0.00015 21.2 0.0 0.00027 20.4 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 PSC74866.1 - 0.00017 20.8 0.3 0.00034 19.8 0.3 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A MTS PF05175.14 PSC74866.1 - 0.00031 20.3 0.0 0.001 18.6 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain PCMT PF01135.19 PSC74866.1 - 0.00038 20.3 0.0 0.00067 19.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AlaDh_PNT_C PF01262.21 PSC74866.1 - 0.00068 19.0 3.5 0.00083 18.7 0.1 2.5 3 0 0 3 3 3 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_3 PF01494.19 PSC74866.1 - 0.00071 18.9 0.4 0.0015 17.9 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Thi4 PF01946.17 PSC74866.1 - 0.0019 17.5 0.1 0.0037 16.5 0.1 1.4 1 0 0 1 1 1 1 Thi4 family TRAM_LAG1_CLN8 PF03798.16 PSC74866.1 - 0.0042 16.8 0.5 0.0077 16.0 0.5 1.4 1 0 0 1 1 1 1 TLC domain HI0933_like PF03486.14 PSC74866.1 - 0.005 15.6 0.1 0.0089 14.8 0.1 1.3 1 0 0 1 1 1 1 HI0933-like protein FtsJ PF01728.19 PSC74866.1 - 0.0053 16.9 0.0 0.049 13.7 0.0 2.1 1 1 0 1 1 1 1 FtsJ-like methyltransferase 3HCDH_N PF02737.18 PSC74866.1 - 0.011 15.6 0.3 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain MCRA PF06100.11 PSC74866.1 - 0.022 13.6 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 MCRA family Methyltransf_18 PF12847.7 PSC74866.1 - 0.022 14.7 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NAD_binding_9 PF13454.6 PSC74866.1 - 0.022 14.7 0.6 9 6.3 0.1 2.6 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF938 PF06080.12 PSC74866.1 - 0.037 13.8 0.0 0.27 10.9 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF938) Ubie_methyltran PF01209.18 PSC74866.1 - 0.053 12.9 0.0 0.084 12.2 0.0 1.2 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Pyr_redox PF00070.27 PSC74866.1 - 0.063 13.8 0.0 0.19 12.3 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase GARS_C PF02843.16 PSC74866.1 - 0.072 13.4 0.0 5.2 7.4 0.0 2.7 2 0 0 2 2 2 0 Phosphoribosylglycinamide synthetase, C domain MetW PF07021.12 PSC74866.1 - 0.11 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW RrnaAD PF00398.20 PSC74866.1 - 0.13 11.3 0.0 0.22 10.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ApbA PF02558.16 PSC74866.1 - 0.17 11.5 0.2 0.55 9.9 0.2 1.9 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Methyltransf_4 PF02390.17 PSC74866.1 - 0.19 11.2 0.0 0.29 10.6 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_9 PF08003.11 PSC74866.1 - 0.22 10.4 0.0 0.35 9.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) Raffinose_syn PF05691.12 PSC74867.1 - 4.2e-66 223.3 0.0 1.5e-19 69.4 0.0 7.6 3 1 3 6 6 6 5 Raffinose synthase or seed imbibition protein Sip1 SET PF00856.28 PSC74867.1 - 1.5e-08 35.2 0.0 6.2e-08 33.2 0.0 2.0 1 1 0 1 1 1 1 SET domain K_channel_TID PF07941.11 PSC74867.1 - 0.013 15.9 7.8 0.013 15.9 7.8 10.7 12 2 1 13 13 13 0 Potassium channel Kv1.4 tandem inactivation domain NAD_Gly3P_dh_C PF07479.14 PSC74868.1 - 2.6e-42 144.4 0.0 6.4e-42 143.2 0.0 1.7 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus NAD_Gly3P_dh_N PF01210.23 PSC74868.1 - 7.5e-40 136.5 0.3 1.5e-39 135.4 0.2 1.6 2 0 0 2 2 2 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus HAD PF12710.7 PSC74868.1 - 3.4e-13 50.4 0.1 2.9e-12 47.4 0.0 2.6 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PSC74868.1 - 1.4e-12 48.3 0.0 3.3e-11 43.9 0.0 2.9 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Semialdhyde_dh PF01118.24 PSC74868.1 - 4.2e-05 24.0 0.0 0.00011 22.7 0.0 1.8 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain PDH PF02153.17 PSC74868.1 - 0.041 12.9 0.0 0.08 11.9 0.0 1.4 1 0 0 1 1 1 0 Prephenate dehydrogenase Put_Phosphatase PF06888.12 PSC74868.1 - 0.067 12.6 0.0 30 3.9 0.0 3.1 3 0 0 3 3 3 0 Putative Phosphatase PsbP PF01789.16 PSC74869.1 - 1.8e-09 37.9 0.0 4.4e-09 36.7 0.0 1.6 2 0 0 2 2 2 1 PsbP DUF4258 PF14076.6 PSC74870.1 - 9.9e-11 41.9 0.0 1.4e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4258) NDUF_B4 PF07225.12 PSC74870.1 - 0.12 12.2 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) GHMP_kinases_N PF00288.26 PSC74871.1 - 3.9e-07 30.2 0.6 3.9e-07 30.2 0.6 2.5 3 0 0 3 3 3 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 PSC74871.1 - 0.0028 18.0 0.0 0.0062 16.9 0.0 1.6 1 0 0 1 1 1 1 GHMP kinases C terminal Pkinase PF00069.25 PSC74872.1 - 1.3e-30 106.6 0.0 1.9e-15 56.9 0.0 3.1 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74872.1 - 1.3e-15 57.5 0.0 1.4e-06 27.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 PSC74872.1 - 0.00015 21.8 3.9 0.00015 21.8 3.9 3.2 3 1 1 4 4 4 1 Phosphotransferase enzyme family Kinase-like PF14531.6 PSC74872.1 - 0.017 14.5 0.0 0.034 13.5 0.0 1.5 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 PSC74872.1 - 0.14 11.5 0.6 0.29 10.4 0.3 1.8 2 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family IHABP4_N PF16174.5 PSC74872.1 - 8.9 6.9 7.8 11 6.6 0.6 2.3 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal AAA PF00004.29 PSC74873.1 - 2.9e-62 208.9 0.0 3.3e-37 127.9 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PSC74873.1 - 4.4e-25 87.2 14.8 3.3e-13 49.2 4.9 3.1 3 0 0 3 3 3 2 AAA+ lid domain AAA_16 PF13191.6 PSC74873.1 - 1e-08 35.8 15.0 1.8e-05 25.2 0.0 4.5 3 2 0 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 PSC74873.1 - 0.0012 18.8 0.4 0.077 13.0 0.0 3.3 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 PSC74873.1 - 0.0013 18.0 0.0 0.0021 17.3 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 PSC74873.1 - 0.0017 18.6 0.2 2.5 8.4 0.0 3.2 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 PSC74873.1 - 0.0022 18.2 1.2 0.017 15.3 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_2 PF07724.14 PSC74873.1 - 0.0034 17.5 0.0 0.19 11.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 PSC74873.1 - 0.0035 17.1 0.0 0.015 15.0 0.0 2.1 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain Vps4_C PF09336.10 PSC74873.1 - 0.013 15.4 0.0 2.5 8.2 0.0 2.5 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain Rad17 PF03215.15 PSC74873.1 - 0.023 14.6 0.0 0.058 13.3 0.0 1.6 2 0 0 2 2 2 0 Rad17 P-loop domain Viral_helicase1 PF01443.18 PSC74873.1 - 0.12 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF1517 PF07466.11 PSC74873.1 - 0.12 12.5 0.3 8 6.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) Aa_trans PF01490.18 PSC74874.1 - 7.4e-50 169.8 19.9 9.4e-50 169.5 19.9 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 PSC74874.1 - 0.23 10.4 22.3 0.0095 15.0 15.4 2.2 2 1 0 2 2 2 0 Tryptophan/tyrosine permease family PseudoU_synth_1 PF01416.20 PSC74875.1 - 8.6e-31 106.6 0.0 7e-28 97.2 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase PDZ_3 PF17815.1 PSC74876.1 - 4e-47 159.7 0.0 5.7e-47 159.2 0.0 1.2 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 PSC74876.1 - 9.6e-23 81.7 1.7 9.6e-23 81.7 1.7 1.8 2 0 0 2 2 2 1 Trypsin-like peptidase domain Trypsin PF00089.26 PSC74876.1 - 8.7e-16 58.4 0.0 1.7e-15 57.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 PSC74876.1 - 3e-10 40.3 0.7 4.2e-07 30.2 0.0 2.9 3 0 0 3 3 3 2 PDZ domain PDZ PF00595.24 PSC74876.1 - 0.00033 20.9 1.2 0.84 10.0 0.0 3.9 3 0 0 3 3 3 1 PDZ domain Peptidase_S46 PF10459.9 PSC74876.1 - 0.0038 16.0 0.1 0.0069 15.1 0.1 1.3 1 0 0 1 1 1 1 Peptidase S46 PDZ_6 PF17820.1 PSC74876.1 - 0.004 17.0 0.1 0.93 9.4 0.0 2.9 2 0 0 2 2 2 1 PDZ domain Peptidase_S39 PF02122.15 PSC74876.1 - 0.0091 15.6 0.0 0.21 11.1 0.0 2.2 2 0 0 2 2 2 1 Peptidase S39 PDZ_1 PF12812.7 PSC74876.1 - 0.11 12.5 0.1 1.1 9.3 0.1 2.5 2 0 0 2 2 2 0 PDZ-like domain Peptidase_S7 PF00949.21 PSC74876.1 - 0.18 11.6 0.3 0.35 10.7 0.3 1.4 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Cyt-b5 PF00173.28 PSC74877.1 - 2.3e-20 72.5 0.0 2.5e-20 72.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Ureidogly_lyase PF04115.12 PSC74878.1 - 2.4e-05 24.2 0.0 2.5e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Ureidoglycolate lyase DUF2009 PF09418.10 PSC74879.1 - 2.1e-208 693.0 0.0 2.6e-208 692.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) Ephrin_rec_like PF07699.13 PSC74879.1 - 3.3e-42 142.0 193.1 1.6e-08 34.2 8.1 20.1 8 4 14 22 22 22 17 Putative ephrin-receptor like NCD3G PF07562.14 PSC74879.1 - 4.5e-15 55.3 123.5 0.0058 16.6 1.3 16.2 11 5 5 18 18 18 13 Nine Cysteines Domain of family 3 GPCR Sulfotransfer_2 PF03567.14 PSC74879.1 - 0.11 12.3 0.1 0.21 11.5 0.1 1.3 1 0 0 1 1 1 0 Sulfotransferase family TH1 PF04858.13 PSC74880.1 - 1.8e-86 291.0 0.0 2.5e-64 218.0 0.0 2.1 2 0 0 2 2 2 2 TH1 protein PhnG PF06754.12 PSC74880.1 - 0.15 12.0 4.4 0.4 10.6 4.4 1.6 1 0 0 1 1 1 0 Phosphonate metabolism protein PhnG PmbA_TldD PF01523.16 PSC74880.1 - 0.19 11.5 3.2 1.4 8.7 0.4 2.3 2 0 0 2 2 2 0 Putative modulator of DNA gyrase UPF0139 PF03669.13 PSC74881.1 - 1.5e-19 69.6 0.0 1.9e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) DUF2985 PF11204.8 PSC74881.1 - 0.082 13.1 0.1 0.11 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2985) AF-4 PF05110.13 PSC74882.1 - 0.0048 15.1 3.5 0.0091 14.2 3.5 1.4 1 0 0 1 1 1 1 AF-4 proto-oncoprotein Glyco_hydro_16 PF00722.21 PSC74883.1 - 1.1e-20 73.8 0.1 4e-20 72.0 0.1 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 PSC74883.1 - 1.3e-06 27.1 0.0 0.0012 17.3 0.0 2.2 1 1 1 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Laminin_G_2 PF02210.24 PSC74883.1 - 0.03 14.9 0.0 0.061 13.9 0.0 1.4 1 0 0 1 1 1 0 Laminin G domain RNase_PH PF01138.21 PSC74884.1 - 5.2e-21 75.5 0.0 1.5e-20 74.0 0.0 1.7 2 0 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 PSC74884.1 - 3e-07 30.4 0.0 7.3e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 YL1 PF05764.13 PSC74884.1 - 0.0015 18.7 2.7 0.0023 18.1 2.7 1.2 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 PSC74884.1 - 3.4 5.8 4.7 4.9 5.3 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_16 PF10294.9 PSC74885.1 - 8.1e-12 45.2 0.8 1.7e-07 31.1 0.1 3.1 3 0 0 3 3 3 2 Lysine methyltransferase MTS PF05175.14 PSC74885.1 - 0.00012 21.7 0.1 0.00021 20.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 PSC74885.1 - 0.00024 20.6 0.0 0.0004 19.9 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 PSC74885.1 - 0.00037 21.1 0.1 0.0011 19.6 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC74885.1 - 0.026 15.1 0.5 0.081 13.6 0.2 2.1 2 0 0 2 2 2 0 Methyltransferase domain Cons_hypoth95 PF03602.15 PSC74885.1 - 0.056 13.1 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_23 PF13489.6 PSC74885.1 - 0.11 12.4 0.0 0.23 11.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 PSC74885.1 - 0.19 11.5 0.4 0.64 9.8 0.2 1.9 2 0 0 2 2 2 0 Methyltransferase domain GRP PF07172.11 PSC74885.1 - 0.85 10.4 12.3 4.5 8.0 5.5 2.5 2 0 0 2 2 2 0 Glycine rich protein family Homeodomain PF00046.29 PSC74886.1 - 0.0011 18.8 0.7 0.0011 18.8 0.7 2.3 3 0 0 3 3 3 1 Homeodomain HTH_23 PF13384.6 PSC74886.1 - 0.018 14.8 0.0 0.048 13.5 0.0 1.7 1 0 0 1 1 1 0 Homeodomain-like domain HTH_17 PF12728.7 PSC74886.1 - 0.13 12.4 0.0 1 9.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain LCM PF04072.14 PSC74887.1 - 1.4e-11 44.7 0.1 1.9e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase Metal_CEHH PF14455.6 PSC74887.1 - 0.18 11.4 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Predicted metal binding domain QueC PF06508.13 PSC74888.1 - 2.6e-28 99.0 0.0 1.1e-27 96.9 0.0 1.8 1 1 0 1 1 1 1 Queuosine biosynthesis protein QueC ATP_bind_3 PF01171.20 PSC74888.1 - 0.0002 21.2 0.0 0.00039 20.2 0.0 1.4 2 0 0 2 2 2 1 PP-loop family AhpC-TSA PF00578.21 PSC74889.1 - 4.7e-30 104.1 0.0 6.7e-30 103.5 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PSC74889.1 - 5.9e-14 52.0 0.0 9.6e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 PSC74889.1 - 1.1e-10 41.2 0.0 1.9e-10 40.4 0.0 1.4 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin AhpC-TSA_2 PF13911.6 PSC74889.1 - 0.001 19.2 0.0 0.0019 18.3 0.0 1.5 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme rve PF00665.26 PSC74890.1 - 7.1e-19 68.1 0.0 1.5e-18 67.1 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC74890.1 - 0.0063 16.3 0.0 0.017 14.9 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Rad51 PF08423.11 PSC74891.1 - 3.6e-18 65.8 0.5 5.5e-17 61.9 0.5 2.0 1 1 0 1 1 1 1 Rad51 RecA PF00154.21 PSC74891.1 - 1.9e-06 27.6 0.1 8.1e-06 25.5 0.0 1.8 2 0 0 2 2 2 1 recA bacterial DNA recombination protein AAA_25 PF13481.6 PSC74891.1 - 4.6e-06 26.4 4.9 8e-05 22.3 4.9 2.3 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.15 PSC74891.1 - 5.7e-06 25.9 0.0 6.2e-05 22.4 0.0 2.1 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain IstB_IS21 PF01695.17 PSC74891.1 - 0.0015 18.3 0.2 0.37 10.5 0.0 2.7 2 1 1 3 3 3 2 IstB-like ATP binding protein ATPase PF06745.13 PSC74891.1 - 0.004 16.5 0.0 0.12 11.7 0.0 2.1 2 0 0 2 2 2 1 KaiC CobU PF02283.16 PSC74891.1 - 0.0084 15.7 0.1 0.042 13.4 0.0 2.0 2 0 0 2 2 2 1 Cobinamide kinase / cobinamide phosphate guanyltransferase SUIM_assoc PF16619.5 PSC74891.1 - 0.051 13.6 1.6 0.12 12.5 1.6 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 YolD PF08863.10 PSC74891.1 - 0.23 11.5 0.0 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 YolD-like protein WD40 PF00400.32 PSC74892.1 - 1.6e-16 60.3 4.5 0.00026 21.7 0.0 6.9 7 0 0 7 7 7 5 WD domain, G-beta repeat XRCC4 PF06632.12 PSC74892.1 - 3.4 6.4 8.4 9.3 5.0 8.4 1.7 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 NAM-associated PF14303.6 PSC74892.1 - 8.4 7.1 12.4 11 6.7 10.7 2.1 1 1 0 1 1 1 0 No apical meristem-associated C-terminal domain LMWPc PF01451.21 PSC74893.1 - 1.3e-10 41.9 0.0 3.4e-10 40.5 0.0 1.7 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase DUF498 PF04430.14 PSC74894.1 - 1.5e-24 86.1 0.0 1.7e-24 86.0 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) TPR_17 PF13431.6 PSC74895.1 - 4.9e-06 26.5 3.0 0.48 10.9 0.1 5.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TOM20_plant PF06552.12 PSC74895.1 - 8.6e-06 25.6 0.1 8.6e-06 25.6 0.1 2.8 3 0 0 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 PAT1 PF09770.9 PSC74895.1 - 0.085 11.1 23.0 0.19 9.9 23.0 1.5 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Fis1_TPR_C PF14853.6 PSC74895.1 - 0.088 12.9 1.7 1.7 8.8 0.2 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat Baculo_PEP_C PF04513.12 PSC74895.1 - 0.35 10.9 12.7 8.8 6.4 0.2 5.4 4 2 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1387 PF07139.11 PSC74895.1 - 8.4 6.0 10.2 20 4.8 10.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) DUF179 PF02622.15 PSC74896.1 - 1.7e-29 102.8 0.0 4.2e-29 101.6 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized ACR, COG1678 DUF179 PF02622.15 PSC74897.1 - 1.6e-29 102.9 0.0 3.9e-29 101.7 0.0 1.6 2 0 0 2 2 2 1 Uncharacterized ACR, COG1678 Glycos_transf_2 PF00535.26 PSC74898.1 - 1.3e-22 80.4 0.0 1.7e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PSC74898.1 - 9.6e-14 51.8 0.0 1.7e-13 51.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.9 PSC74898.1 - 4.5e-07 29.6 0.0 0.0037 16.8 0.0 2.2 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 PSC74898.1 - 0.0001 21.9 0.0 0.00015 21.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_trans_2_3 PF13632.6 PSC74898.1 - 0.018 15.0 0.0 0.029 14.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Cupin_8 PF13621.6 PSC74899.1 - 4.1e-30 105.3 0.0 1.2e-29 103.8 0.0 1.7 2 0 0 2 2 2 1 Cupin-like domain KH_1 PF00013.29 PSC74899.1 - 1.6e-16 59.9 0.1 2.6e-16 59.2 0.1 1.4 1 0 0 1 1 1 1 KH domain WW PF00397.26 PSC74899.1 - 2.2e-08 34.0 0.2 2.2e-08 34.0 0.2 1.7 2 0 0 2 2 2 1 WW domain KH_4 PF13083.6 PSC74899.1 - 2.3e-05 24.2 0.0 4.9e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 KH domain KH_2 PF07650.17 PSC74899.1 - 0.0025 17.6 0.1 0.0044 16.8 0.1 1.3 1 0 0 1 1 1 1 KH domain Cupin_4 PF08007.12 PSC74899.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Cupin superfamily protein MOEP19 PF16005.5 PSC74899.1 - 0.044 13.8 0.0 0.083 12.9 0.0 1.3 1 0 0 1 1 1 0 KH-like RNA-binding domain JmjC PF02373.22 PSC74899.1 - 0.14 12.6 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 JmjC domain, hydroxylase Cupin_2 PF07883.11 PSC74899.1 - 0.16 11.7 0.0 0.42 10.4 0.0 1.7 1 0 0 1 1 1 0 Cupin domain Alpha-amyl_C2 PF07821.12 PSC74900.1 - 3.2e-20 72.1 0.7 6.7e-20 71.1 0.7 1.6 1 0 0 1 1 1 1 Alpha-amylase C-terminal beta-sheet domain Alpha-amylase PF00128.24 PSC74900.1 - 8.1e-17 61.8 0.0 4e-16 59.5 0.0 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.16 PSC74900.1 - 0.0017 16.6 0.0 0.0039 15.5 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 70 ACT PF01842.25 PSC74900.1 - 0.0032 17.2 0.1 0.0085 15.8 0.1 1.7 1 0 0 1 1 1 1 ACT domain ACT_4 PF13291.6 PSC74900.1 - 0.091 13.4 0.0 0.18 12.4 0.0 1.4 1 0 0 1 1 1 0 ACT domain DUF2722 PF10846.8 PSC74901.1 - 0.059 12.3 25.4 0.039 12.9 2.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Lycopene_cycl PF05834.12 PSC74902.1 - 4.7e-38 131.2 7.6 3.6e-14 52.6 0.7 4.1 2 1 2 4 4 4 4 Lycopene cyclase protein CheR_N PF03705.15 PSC74902.1 - 0.14 11.9 0.2 0.3 10.9 0.2 1.5 1 0 0 1 1 1 0 CheR methyltransferase, all-alpha domain SNF2_N PF00176.23 PSC74903.1 - 5.4e-66 222.7 0.2 9.9e-66 221.8 0.2 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain SBP_bac_6 PF13343.6 PSC74903.1 - 4.9e-22 78.5 0.0 1.1e-21 77.3 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding protein Helicase_C PF00271.31 PSC74903.1 - 6.1e-17 62.0 0.1 3.7e-16 59.4 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SBP_bac_8 PF13416.6 PSC74903.1 - 5.9e-13 49.3 2.6 1.3e-12 48.1 0.0 2.5 3 0 0 3 3 3 1 Bacterial extracellular solute-binding protein ResIII PF04851.15 PSC74903.1 - 1.1e-11 45.1 0.0 2.7e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 PSC74903.1 - 5.2e-06 26.3 0.0 1.3e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase QLQ PF08880.11 PSC74903.1 - 0.00011 21.9 0.0 0.0004 20.1 0.0 2.0 1 0 0 1 1 1 1 QLQ AAA_19 PF13245.6 PSC74903.1 - 0.019 15.3 0.5 0.39 11.0 0.0 2.8 2 1 0 2 2 2 0 AAA domain AAA_14 PF13173.6 PSC74903.1 - 0.024 14.7 0.1 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF1995 PF09353.10 PSC74905.1 - 1.8e-43 148.9 0.1 1.8e-43 148.9 0.1 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF1995) Chloroa_b-bind PF00504.21 PSC74905.1 - 5.1e-08 33.6 2.2 1e-05 26.1 2.2 2.6 1 1 0 1 1 1 1 Chlorophyll A-B binding protein Glyco_transf_5 PF08323.11 PSC74906.1 - 5.8e-64 216.1 0.2 7.8e-64 215.7 0.2 1.2 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 PSC74906.1 - 6.5e-16 58.3 0.0 1.1e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PSC74906.1 - 1.3e-11 45.1 0.0 3.1e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Vac14_Fig4_bd PF11916.8 PSC74907.1 - 1.6e-37 128.9 0.4 1.6e-37 128.9 0.4 1.9 2 0 0 2 2 2 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 PSC74907.1 - 1.7e-30 105.4 0.0 1.6e-29 102.4 0.0 2.5 3 0 0 3 3 2 1 Vacuolar 14 Fab1-binding region DNase-RNase PF02577.14 PSC74907.1 - 1.5e-12 47.2 0.0 3.8e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Bifunctional nuclease HEAT PF02985.22 PSC74907.1 - 5.5e-08 32.4 16.6 0.00087 19.3 0.1 6.9 7 0 0 7 7 7 2 HEAT repeat Tti2 PF10521.9 PSC74907.1 - 4.8e-05 23.0 0.2 0.11 12.0 0.1 3.4 2 1 1 3 3 3 1 Tti2 family Cnd1 PF12717.7 PSC74907.1 - 0.00019 21.5 2.9 1.3 9.1 0.0 4.2 2 2 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Dopey_N PF04118.14 PSC74907.1 - 0.00019 20.7 1.4 0.17 11.0 0.0 2.8 2 1 0 2 2 2 2 Dopey, N-terminal HEAT_2 PF13646.6 PSC74907.1 - 0.00025 21.4 14.2 0.023 15.1 0.0 5.8 3 2 1 5 5 5 2 HEAT repeats UVR PF02151.19 PSC74907.1 - 0.0042 16.8 0.8 0.016 14.9 0.8 2.1 1 0 0 1 1 1 1 UvrB/uvrC motif HEAT_EZ PF13513.6 PSC74907.1 - 0.037 14.6 0.3 0.037 14.6 0.3 7.1 5 3 4 9 9 9 0 HEAT-like repeat MMS19_C PF12460.8 PSC74907.1 - 1 8.4 8.3 2.3 7.2 0.8 3.7 2 2 2 4 4 4 0 RNAPII transcription regulator C-terminal RhlB PF12300.8 PSC74907.1 - 4.9 7.3 11.0 4.1 7.5 5.2 2.9 3 0 0 3 3 3 0 ATP-dependent RNA helicase RhlB adh_short PF00106.25 PSC74908.1 - 2.2e-16 59.9 0.4 2.6e-16 59.6 0.4 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC74908.1 - 4.7e-15 55.8 0.6 5.8e-15 55.5 0.6 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC74908.1 - 8.9e-05 22.5 0.6 0.00013 21.9 0.6 1.2 1 0 0 1 1 1 1 KR domain NmrA PF05368.13 PSC74908.1 - 0.00042 19.9 0.1 0.00073 19.2 0.1 1.5 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 PSC74908.1 - 0.0009 18.8 0.1 0.0011 18.5 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 PSC74908.1 - 0.0013 18.2 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) F420_oxidored PF03807.17 PSC74908.1 - 0.049 14.2 0.5 0.17 12.5 0.1 2.2 2 1 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 PSC74908.1 - 0.091 12.6 0.1 0.14 12.0 0.1 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain SBBP PF06739.11 PSC74909.1 - 0.11 12.5 3.3 3.9 7.5 0.2 3.3 3 0 0 3 3 3 0 Beta-propeller repeat DUF5128 PF17170.4 PSC74909.1 - 0.13 11.4 0.1 13 4.8 0.0 2.9 3 0 0 3 3 3 0 6-bladed beta-propeller DUF4602 PF15375.6 PSC74910.1 - 4.7e-18 65.8 7.2 4.7e-18 65.8 7.2 3.0 2 2 0 3 3 3 1 Domain of unknown function (DUF4602) DUF3446 PF11928.8 PSC74910.1 - 0.13 12.5 2.6 0.31 11.4 2.6 1.5 1 0 0 1 1 1 0 Early growth response N-terminal domain tRNA-synt_1e PF01406.19 PSC74911.1 - 1e-115 386.2 0.0 2e-115 385.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 PSC74911.1 - 1.8e-06 26.9 0.3 0.00029 19.7 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 PSC74911.1 - 0.00043 20.7 0.0 0.0024 18.3 0.0 2.4 1 0 0 1 1 1 1 DALR domain tRNA-synt_1c PF00749.21 PSC74911.1 - 0.0094 14.9 0.0 0.019 13.9 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1f PF01921.18 PSC74911.1 - 0.012 14.5 0.0 0.39 9.6 0.0 2.2 2 0 0 2 2 2 0 tRNA synthetases class I (K) Sugar_tr PF00083.24 PSC74912.1 - 1.2e-86 291.4 12.1 1.6e-86 291.0 12.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PSC74912.1 - 8.2e-22 77.6 16.1 1.1e-21 77.2 16.1 1.0 1 0 0 1 1 1 1 Major Facilitator Superfamily Saf_2TM PF18303.1 PSC74912.1 - 1.1 8.9 5.8 1 9.0 0.2 2.6 2 1 0 2 2 2 0 SAVED-fused 2TM effector domain MFS_1_like PF12832.7 PSC74912.1 - 2.6 6.8 15.8 0.12 11.2 3.4 2.6 2 1 0 2 2 2 0 MFS_1 like family DUF2854 PF11016.8 PSC74913.1 - 3.3e-47 160.1 0.2 1.4e-46 158.1 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2854) WD40 PF00400.32 PSC74914.1 - 2.2e-14 53.6 12.2 0.0021 18.9 0.1 7.6 7 0 0 7 7 7 3 WD domain, G-beta repeat PQQ_3 PF13570.6 PSC74914.1 - 1.7e-05 25.2 2.7 0.00062 20.2 0.3 4.5 7 0 0 7 7 7 2 PQQ-like domain PQQ PF01011.21 PSC74914.1 - 4e-05 23.3 0.2 0.00084 19.1 0.0 3.2 3 1 0 3 3 3 1 PQQ enzyme repeat PQQ_2 PF13360.6 PSC74914.1 - 0.00011 21.9 0.2 0.00027 20.6 0.2 1.8 1 0 0 1 1 1 1 PQQ-like domain ANAPC4_WD40 PF12894.7 PSC74914.1 - 0.029 14.7 0.1 24 5.3 0.0 3.4 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DNase-RNase PF02577.14 PSC74915.1 - 1e-36 125.4 0.0 1.6e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Bifunctional nuclease UVR PF02151.19 PSC74915.1 - 3.9e-09 35.9 7.7 2e-05 24.2 0.4 2.5 2 0 0 2 2 2 2 UvrB/uvrC motif FSIP1 PF15554.6 PSC74915.1 - 0.011 14.8 0.0 0.3 10.1 0.0 2.0 2 0 0 2 2 2 0 FSIP1 family Ndc80_HEC PF03801.13 PSC74916.1 - 4.1e-37 127.1 0.0 1.8e-18 66.6 0.0 2.8 3 0 0 3 3 3 2 HEC/Ndc80p family Shugoshin_C PF07557.11 PSC74916.1 - 4.1e-05 23.3 3.2 0.0001 22.0 3.2 1.8 1 0 0 1 1 1 1 Shugoshin C terminus DUF5595 PF18077.1 PSC74916.1 - 0.00099 19.1 0.1 0.00099 19.1 0.1 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF5595) Spc7 PF08317.11 PSC74916.1 - 0.0019 17.2 6.7 0.0019 17.2 6.7 3.4 3 0 0 3 3 3 3 Spc7 kinetochore protein Ser_hydrolase PF06821.13 PSC74916.1 - 0.026 14.4 0.7 0.093 12.6 0.7 1.9 1 0 0 1 1 1 0 Serine hydrolase Fib_alpha PF08702.10 PSC74916.1 - 0.038 14.2 0.4 0.038 14.2 0.4 3.6 4 1 0 4 4 4 0 Fibrinogen alpha/beta chain family YabA PF06156.13 PSC74916.1 - 1.5 9.5 28.4 2.2 9.0 3.4 5.5 3 2 1 4 4 4 0 Initiation control protein YabA Ribosomal_L13e PF01294.18 PSC74917.1 - 6e-70 234.7 5.7 6e-70 234.7 5.7 2.1 2 0 0 2 2 2 1 Ribosomal protein L13e Sad1_UNC PF07738.13 PSC74918.1 - 8.4e-22 77.6 0.0 5.6e-10 39.4 0.0 2.6 2 1 0 2 2 2 2 Sad1 / UNC-like C-terminal Syntaxin-6_N PF09177.11 PSC74918.1 - 0.087 13.4 0.1 15 6.2 0.0 2.2 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Spc7 PF08317.11 PSC74918.1 - 0.14 11.0 0.6 0.2 10.5 0.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein SMP_2 PF10144.9 PSC74918.1 - 0.24 11.0 1.7 0.58 9.8 1.7 1.5 2 0 0 2 2 2 0 Bacterial virulence factor haemolysin DUF848 PF05852.11 PSC74918.1 - 0.26 11.4 0.5 0.42 10.7 0.1 1.5 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) MscS_porin PF12795.7 PSC74918.1 - 0.39 10.2 9.4 0.56 9.7 9.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain TPR_MLP1_2 PF07926.12 PSC74918.1 - 0.46 10.6 8.5 1.4 8.9 7.5 2.0 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Uso1_p115_C PF04871.13 PSC74918.1 - 0.56 10.6 2.2 0.89 9.9 2.2 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region ISG65-75 PF11727.8 PSC74918.1 - 0.73 9.0 6.0 1.1 8.4 6.0 1.2 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF3584 PF12128.8 PSC74918.1 - 0.91 6.9 5.1 1.2 6.6 5.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) HR1 PF02185.16 PSC74918.1 - 1.5 9.0 4.9 3.3 7.9 3.2 2.3 1 1 1 2 2 2 0 Hr1 repeat DUF3450 PF11932.8 PSC74918.1 - 3.2 7.0 8.3 4.6 6.5 8.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DLIC PF05783.11 PSC74919.1 - 0.0084 15.0 2.6 0.017 14.0 2.6 1.4 1 0 0 1 1 1 1 Dynein light intermediate chain (DLIC) DUF2046 PF09755.9 PSC74919.1 - 0.066 12.4 0.3 0.066 12.4 0.3 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein H4 (DUF2046) Golgin_A5 PF09787.9 PSC74919.1 - 0.15 11.5 21.4 0.08 12.4 1.4 2.2 2 0 0 2 2 2 0 Golgin subfamily A member 5 KASH_CCD PF14662.6 PSC74919.1 - 0.17 11.7 24.2 0.021 14.6 14.1 2.2 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH GAT PF03127.14 PSC74919.1 - 0.23 11.8 2.9 8.8 6.7 0.2 3.1 3 0 0 3 3 3 0 GAT domain CENP-F_leu_zip PF10473.9 PSC74919.1 - 0.33 11.0 23.0 1.2 9.2 0.8 3.6 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Med8 PF10232.9 PSC74919.1 - 0.8 9.3 5.9 7.5 6.1 0.2 2.8 3 0 0 3 3 3 0 Mediator of RNA polymerase II transcription complex subunit 8 HAUS-augmin3 PF14932.6 PSC74919.1 - 2 7.9 25.3 2.5 7.6 3.2 2.3 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 3 BLOC1_2 PF10046.9 PSC74919.1 - 2.8 8.3 9.9 18 5.7 0.9 3.9 4 0 0 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Spc7 PF08317.11 PSC74919.1 - 3.8 6.3 30.3 0.041 12.8 5.2 2.8 2 1 0 2 2 2 0 Spc7 kinetochore protein V_ATPase_I PF01496.19 PSC74919.1 - 3.8 5.3 8.5 0.43 8.4 2.9 1.8 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family YabA PF06156.13 PSC74919.1 - 4.7 7.9 15.2 12 6.7 1.0 3.5 2 2 1 3 3 3 0 Initiation control protein YabA DUF1664 PF07889.12 PSC74919.1 - 5.2 7.1 7.6 5.8 7.0 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Med9 PF07544.13 PSC74919.1 - 7.1 6.8 16.2 0.61 10.2 2.3 3.8 3 0 0 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 UPF0242 PF06785.11 PSC74919.1 - 9.4 6.3 22.1 0.35 10.9 0.8 3.1 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus KLRAQ PF10205.9 PSC74919.1 - 9.5 6.5 17.2 0.16 12.2 1.0 3.9 2 2 2 4 4 4 0 Predicted coiled-coil domain-containing protein Angiomotin_C PF12240.8 PSC74920.1 - 0.042 13.4 10.0 0.13 11.9 10.0 1.8 1 0 0 1 1 1 0 Angiomotin C terminal TRAF_BIRC3_bd PF16673.5 PSC74920.1 - 0.056 13.2 0.3 3.3 7.6 0.1 2.7 2 0 0 2 2 2 0 TNF receptor-associated factor BIRC3 binding domain Baculo_PEP_C PF04513.12 PSC74920.1 - 0.086 12.9 2.0 1.1 9.3 0.0 3.3 3 2 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Vps5 PF09325.10 PSC74920.1 - 0.14 11.7 2.3 0.33 10.5 0.2 2.5 1 1 2 3 3 3 0 Vps5 C terminal like Spectrin PF00435.21 PSC74920.1 - 0.67 10.5 7.8 1.3 9.5 1.9 3.8 3 1 2 5 5 5 0 Spectrin repeat Tropomyosin_1 PF12718.7 PSC74920.1 - 1.5 9.0 10.3 0.37 10.9 2.0 2.7 2 1 1 3 3 3 0 Tropomyosin like DUF1993 PF09351.10 PSC74920.1 - 2.9 8.0 7.7 0.36 11.0 1.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF1993) GRIP PF01465.20 PSC74921.1 - 1.7e-05 24.6 0.0 4.1e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 GRIP domain Ebp2 PF05890.12 PSC74922.1 - 4.6e-70 236.2 10.2 6.2e-70 235.8 10.2 1.1 1 0 0 1 1 1 1 Eukaryotic rRNA processing protein EBP2 Presenilin PF01080.17 PSC74922.1 - 3 6.5 5.8 4.8 5.8 5.8 1.3 1 0 0 1 1 1 0 Presenilin DUF2098 PF09871.9 PSC74922.1 - 7.5 7.0 8.9 32 5.0 8.9 2.1 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) Ephrin_rec_like PF07699.13 PSC74923.1 - 9.1e-40 134.2 176.4 1.9e-09 37.1 7.6 19.8 8 5 13 21 21 21 14 Putative ephrin-receptor like Methyltr_RsmB-F PF01189.17 PSC74923.1 - 4.7e-37 127.6 0.0 1.1e-17 64.3 0.0 2.4 1 1 1 2 2 2 2 16S rRNA methyltransferase RsmB/F NCD3G PF07562.14 PSC74923.1 - 1.8e-15 56.6 119.6 0.0031 17.4 8.0 14.6 12 3 0 14 14 14 9 Nine Cysteines Domain of family 3 GPCR FtsJ PF01728.19 PSC74923.1 - 4.7e-08 33.3 0.0 9.9e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 PSC74923.1 - 2.5e-06 27.3 0.0 0.0049 16.7 0.0 2.4 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 PSC74923.1 - 0.00026 20.9 0.0 0.00075 19.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PUA PF01472.20 PSC74923.1 - 0.00035 20.5 0.2 0.001 18.9 0.1 1.9 2 0 0 2 2 2 1 PUA domain PCMT PF01135.19 PSC74923.1 - 0.06 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 PSC74923.1 - 0.06 14.0 0.0 2 9.1 0.0 2.9 1 1 0 1 1 1 0 Methyltransferase domain Ubie_methyltran PF01209.18 PSC74923.1 - 0.12 11.7 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_24 PF13578.6 PSC74923.1 - 0.17 12.9 0.0 0.61 11.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain SUIM_assoc PF16619.5 PSC74923.1 - 0.55 10.3 4.7 1.5 8.9 4.7 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Pro_isomerase PF00160.21 PSC74924.1 - 2.2e-52 177.5 0.0 8.4e-52 175.6 0.0 1.9 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 PSC74924.1 - 4e-12 46.4 0.5 0.0028 18.4 0.0 4.7 5 0 0 5 5 5 3 WD domain, G-beta repeat AMP-binding PF00501.28 PSC74925.1 - 1.1e-102 343.9 0.0 1.3e-102 343.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PSC74925.1 - 0.00011 23.0 1.1 0.00074 20.4 0.5 2.6 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain TFIIA PF03153.13 PSC74926.1 - 0.05 13.6 8.4 0.057 13.4 8.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DSBA PF01323.20 PSC74926.1 - 2.9 7.6 9.7 6.4 6.5 9.7 1.5 1 0 0 1 1 1 0 DSBA-like thioredoxin domain UNC-50 PF05216.13 PSC74927.1 - 2e-78 263.0 7.9 2.3e-78 262.8 7.9 1.0 1 0 0 1 1 1 1 UNC-50 family Promethin PF16015.5 PSC74927.1 - 0.24 11.4 0.1 0.24 11.4 0.1 3.0 2 1 0 2 2 2 0 Promethin SH PF01445.17 PSC74927.1 - 1.1 9.3 5.1 1.3 9.1 0.1 2.7 2 1 0 2 2 2 0 Viral small hydrophobic protein ATG7_N PF16420.5 PSC74928.1 - 9.5e-59 199.5 0.0 1.2e-58 199.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 PSC74928.1 - 4.5e-42 144.1 0.0 8e-42 143.3 0.0 1.3 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 PSC74928.1 - 0.09 12.1 0.0 0.38 10.1 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 PSC74928.1 - 0.3 11.2 0.2 0.99 9.5 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase SprT-like PF10263.9 PSC74929.1 - 1.1e-21 76.8 0.0 1.6e-21 76.3 0.0 1.2 1 0 0 1 1 1 1 SprT-like family Peptidase_M91 PF14891.6 PSC74929.1 - 0.036 14.4 0.0 0.065 13.6 0.0 1.5 1 0 0 1 1 1 0 Effector protein Fe_hyd_lg_C PF02906.14 PSC74930.1 - 3.8e-90 301.8 0.0 6.6e-90 301.0 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 PSC74930.1 - 3.1e-23 81.6 0.7 6.4e-23 80.6 0.7 1.5 1 0 0 1 1 1 1 Iron hydrogenase small subunit NHL PF01436.21 PSC74931.1 - 2.1e-42 141.0 9.3 2.5e-05 24.1 0.0 11.1 12 0 0 12 12 12 10 NHL repeat SGL PF08450.12 PSC74931.1 - 3.1e-14 53.1 6.8 0.00024 20.8 0.1 8.5 5 3 2 8 8 8 3 SMP-30/Gluconolactonase/LRE-like region Phytase-like PF13449.6 PSC74931.1 - 2.3e-06 27.8 0.0 0.47 10.3 0.0 5.5 6 2 1 8 8 8 2 Esterase-like activity of phytase SBBP PF06739.11 PSC74931.1 - 0.00017 21.5 28.2 0.47 10.5 0.0 8.6 10 1 1 11 11 11 3 Beta-propeller repeat Toxin_12 PF07740.12 PSC74931.1 - 0.03 15.0 8.0 0.03 15.0 8.0 3.7 3 1 0 3 3 3 0 Ion channel inhibitory toxin SdiA-regulated PF06977.11 PSC74931.1 - 0.16 11.2 0.2 50 3.0 0.0 4.0 4 1 0 4 4 4 0 SdiA-regulated DUF5128 PF17170.4 PSC74931.1 - 0.43 9.7 0.7 4.4 6.4 0.1 2.6 3 0 0 3 3 3 0 6-bladed beta-propeller NHL PF01436.21 PSC74932.1 - 4.6e-30 102.1 4.0 0.0012 18.8 0.1 7.4 7 0 0 7 7 7 7 NHL repeat SGL PF08450.12 PSC74932.1 - 6.7e-09 35.7 3.4 0.71 9.4 0.0 6.0 3 2 2 6 6 6 4 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 PSC74932.1 - 2.7e-06 27.3 18.5 0.2 11.7 0.0 6.8 7 1 1 8 8 8 4 Beta-propeller repeat Phytase-like PF13449.6 PSC74932.1 - 0.0045 17.0 0.0 1.2 9.1 0.0 4.2 3 1 1 5 5 5 1 Esterase-like activity of phytase Ribonuc_red_sm PF00268.21 PSC74933.1 - 1.3e-79 267.5 0.0 1.6e-79 267.3 0.0 1.0 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Malic_M PF03949.15 PSC74934.1 - 1.7e-89 299.5 0.7 2.2e-89 299.2 0.7 1.1 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 PSC74934.1 - 5.2e-69 231.7 0.0 8.9e-69 230.9 0.0 1.4 1 0 0 1 1 1 1 Malic enzyme, N-terminal domain FAST_1 PF06743.15 PSC74935.1 - 3.8e-26 90.8 1.1 0.0013 18.7 0.0 9.7 5 2 7 12 12 12 9 FAST kinase-like protein, subdomain 1 RAP PF08373.10 PSC74935.1 - 3.4e-07 30.3 0.0 5.8e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 RAP domain MTES_1575 PF18741.1 PSC74935.1 - 0.024 14.8 0.0 0.045 13.9 0.0 1.5 1 0 0 1 1 1 0 REase_MTES_1575 LCM PF04072.14 PSC74936.1 - 7.8e-22 78.1 0.1 3.9e-21 75.8 0.0 2.2 2 1 0 2 2 2 1 Leucine carboxyl methyltransferase PLAC8 PF04749.17 PSC74936.1 - 5.3e-09 37.0 7.0 1.2e-08 35.8 7.0 1.7 1 0 0 1 1 1 1 PLAC8 family SUIM_assoc PF16619.5 PSC74936.1 - 0.00082 19.4 4.1 0.071 13.2 6.8 2.6 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 RAB3GAP2_N PF14655.6 PSC74936.1 - 0.0042 16.4 0.9 0.0073 15.6 0.9 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Spt20 PF12090.8 PSC74936.1 - 0.92 9.1 10.1 1.5 8.4 10.1 1.2 1 0 0 1 1 1 0 Spt20 family CcmD PF04995.14 PSC74936.1 - 3.5 7.8 6.6 15 5.8 2.3 3.2 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) LCM PF04072.14 PSC74937.1 - 7.4e-22 78.2 0.1 3.8e-21 75.9 0.0 2.2 2 1 0 2 2 2 1 Leucine carboxyl methyltransferase PLAC8 PF04749.17 PSC74937.1 - 5.2e-09 37.0 7.0 1.2e-08 35.9 7.0 1.7 1 0 0 1 1 1 1 PLAC8 family SUIM_assoc PF16619.5 PSC74937.1 - 0.00017 21.6 2.0 0.069 13.2 6.8 2.6 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 RAB3GAP2_N PF14655.6 PSC74937.1 - 0.0041 16.4 0.9 0.0071 15.7 0.9 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Spt20 PF12090.8 PSC74937.1 - 0.89 9.1 10.1 1.4 8.4 10.1 1.2 1 0 0 1 1 1 0 Spt20 family CcmD PF04995.14 PSC74937.1 - 3.9 7.6 6.6 14 5.8 2.3 3.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) LCM PF04072.14 PSC74938.1 - 1.3e-21 77.4 0.7 1.5e-20 73.9 0.0 2.5 3 0 0 3 3 3 1 Leucine carboxyl methyltransferase PLAC8 PF04749.17 PSC74938.1 - 4.8e-09 37.1 7.0 1.2e-08 35.8 7.0 1.8 1 0 0 1 1 1 1 PLAC8 family SUIM_assoc PF16619.5 PSC74938.1 - 0.00086 19.3 4.2 0.072 13.2 6.8 2.6 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 RAB3GAP2_N PF14655.6 PSC74938.1 - 0.0043 16.4 0.9 0.0074 15.6 0.9 1.3 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Spt20 PF12090.8 PSC74938.1 - 0.92 9.1 10.1 1.5 8.4 10.1 1.2 1 0 0 1 1 1 0 Spt20 family CcmD PF04995.14 PSC74938.1 - 4.9 7.3 6.6 15 5.8 2.3 2.9 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) Syntaxin-6_N PF09177.11 PSC74939.1 - 1e-18 67.7 0.2 1.1e-17 64.4 0.0 2.1 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.19 PSC74939.1 - 1e-08 35.0 5.3 1.3e-08 34.7 0.1 2.8 3 0 0 3 3 3 1 SNARE domain DUF4164 PF13747.6 PSC74939.1 - 0.089 13.1 7.0 1.5 9.2 0.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) Nup88 PF10168.9 PSC74939.1 - 0.11 10.3 0.5 0.15 9.8 0.5 1.2 1 0 0 1 1 1 0 Nuclear pore component DUF16 PF01519.16 PSC74939.1 - 0.55 10.8 2.9 0.94 10.0 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function DUF16 Metallophos PF00149.28 PSC74940.1 - 3.9e-09 37.3 0.0 1.4e-08 35.5 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PSC74940.1 - 0.00013 22.2 0.0 0.026 14.7 0.0 2.2 2 0 0 2 2 2 2 Calcineurin-like phosphoesterase superfamily domain Vps39_2 PF10367.9 PSC74941.1 - 2.1e-13 50.7 0.0 8.1e-13 48.8 0.0 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.9 PSC74941.1 - 3.6e-13 49.7 0.0 7.1e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 1 CNH PF00780.22 PSC74941.1 - 7.4e-08 32.3 0.0 1.3e-07 31.5 0.0 1.3 1 0 0 1 1 1 1 CNH domain LRR_8 PF13855.6 PSC74941.1 - 1.1e-07 31.5 0.5 0.0049 16.6 0.0 2.4 1 1 1 2 2 2 2 Leucine rich repeat Clathrin PF00637.20 PSC74941.1 - 2.5e-05 24.2 0.0 1.2 9.1 0.0 3.1 3 0 0 3 3 3 2 Region in Clathrin and VPS PQQ_3 PF13570.6 PSC74941.1 - 0.0085 16.6 3.9 0.32 11.5 0.2 4.0 3 0 0 3 3 3 1 PQQ-like domain FliO PF04347.13 PSC74941.1 - 0.023 15.0 0.6 0.17 12.2 0.0 2.8 2 0 0 2 2 2 0 Flagellar biosynthesis protein, FliO LRR_4 PF12799.7 PSC74941.1 - 0.098 13.1 2.3 8 7.0 0.6 2.6 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) RPN7 PF10602.9 PSC74942.1 - 9.7e-52 175.2 0.5 1.6e-51 174.4 0.5 1.4 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 PSC74942.1 - 9.5e-14 51.8 0.0 2.3e-13 50.6 0.0 1.7 1 0 0 1 1 1 1 PCI domain TPR_14 PF13428.6 PSC74942.1 - 2.6 9.1 10.3 7.3 7.7 0.1 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat PXA PF02194.15 PSC74943.1 - 2.1e-25 89.7 0.1 5.6e-25 88.4 0.0 1.8 2 0 0 2 2 2 1 PXA domain PX PF00787.24 PSC74943.1 - 2.4e-20 72.6 0.1 4.8e-20 71.6 0.1 1.5 1 0 0 1 1 1 1 PX domain Nexin_C PF08628.12 PSC74943.1 - 4.9e-18 65.7 0.1 5.6e-17 62.3 0.0 2.5 2 0 0 2 2 2 1 Sorting nexin C terminal Catalase PF00199.19 PSC74943.1 - 0.15 11.2 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Catalase EphA2_TM PF14575.6 PSC74944.1 - 5.1e-05 24.1 0.0 0.42 11.5 0.0 2.5 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain LPG_synthase_TM PF03706.13 PSC74944.1 - 0.053 13.1 9.4 0.039 13.5 0.6 2.9 3 0 0 3 3 3 0 Lysylphosphatidylglycerol synthase TM region LapA_dom PF06305.11 PSC74944.1 - 0.11 12.3 6.3 0.097 12.5 0.9 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Rax2 PF12768.7 PSC74944.1 - 0.15 11.5 0.0 1.4 8.3 0.0 2.0 2 0 0 2 2 2 0 Cortical protein marker for cell polarity SARAF PF06682.12 PSC74944.1 - 0.15 11.7 6.1 0.1 12.3 0.1 2.7 3 0 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis Syndecan PF01034.20 PSC74944.1 - 0.15 12.0 2.0 1.3 8.9 0.2 2.6 2 0 0 2 2 2 0 Syndecan domain ACT_7 PF13840.6 PSC74944.1 - 1.7 8.5 3.0 13 5.6 0.2 2.5 2 0 0 2 2 2 0 ACT domain EphA2_TM PF14575.6 PSC74945.1 - 5.5e-05 24.0 0.0 0.43 11.5 0.0 2.5 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain LPG_synthase_TM PF03706.13 PSC74945.1 - 0.057 12.9 9.4 0.041 13.4 0.6 2.9 3 0 0 3 3 3 0 Lysylphosphatidylglycerol synthase TM region LapA_dom PF06305.11 PSC74945.1 - 0.069 13.0 5.5 0.1 12.5 0.9 2.8 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF4328 PF14219.6 PSC74945.1 - 0.14 11.7 4.7 1.8 8.1 1.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4328) Rax2 PF12768.7 PSC74945.1 - 0.16 11.4 0.0 1.5 8.3 0.0 2.0 2 0 0 2 2 2 0 Cortical protein marker for cell polarity SARAF PF06682.12 PSC74945.1 - 0.16 11.6 6.1 0.1 12.2 0.1 2.7 3 0 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis Syndecan PF01034.20 PSC74945.1 - 0.17 11.9 2.0 1.4 8.9 0.2 2.6 2 0 0 2 2 2 0 Syndecan domain ACT_7 PF13840.6 PSC74945.1 - 1.8 8.4 3.0 14 5.6 0.2 2.4 2 0 0 2 2 2 0 ACT domain SNF2_N PF00176.23 PSC74946.1 - 2.8e-19 69.1 0.1 5.8e-10 38.4 0.0 3.5 2 1 1 3 3 3 3 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC74946.1 - 8.8e-16 58.2 0.0 1.9e-15 57.2 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain TFIIF_alpha PF05793.12 PSC74946.1 - 0.00031 19.5 2.7 0.00031 19.5 2.7 2.0 2 0 0 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) YL1 PF05764.13 PSC74946.1 - 0.00086 19.5 1.9 0.00086 19.5 1.9 3.1 4 0 0 4 4 4 1 YL1 nuclear protein Myb_DNA-binding PF00249.31 PSC74946.1 - 0.0041 17.3 0.1 0.022 14.9 0.0 2.4 2 0 0 2 2 2 1 Myb-like DNA-binding domain ResIII PF04851.15 PSC74946.1 - 0.073 13.1 0.0 0.25 11.4 0.0 1.8 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit MscL PF01741.18 PSC74947.1 - 2.7e-24 85.8 0.0 3.7e-24 85.3 0.0 1.2 1 0 0 1 1 1 1 Large-conductance mechanosensitive channel, MscL UPF0547 PF10571.9 PSC74947.1 - 0.043 13.9 4.6 0.078 13.1 4.6 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0547 DZR PF12773.7 PSC74947.1 - 0.11 12.6 3.4 0.18 11.9 3.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-tcix PF14952.6 PSC74947.1 - 0.16 11.6 2.0 0.29 10.8 2.0 1.3 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding Pkinase PF00069.25 PSC74948.1 - 2e-69 233.9 0.0 2.6e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74948.1 - 5.9e-45 153.6 0.0 8.8e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PSC74948.1 - 6.2e-05 22.4 0.2 0.00035 20.0 0.1 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PSC74948.1 - 8.2e-05 22.3 0.1 0.00035 20.2 0.0 1.8 2 0 0 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.9 PSC74948.1 - 0.0057 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL DUF3543 PF12063.8 PSC74948.1 - 0.0094 15.4 0.2 0.032 13.6 0.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_fungal PF17667.1 PSC74948.1 - 0.11 11.3 0.6 0.55 8.9 0.0 2.1 2 1 0 3 3 3 0 Fungal protein kinase Pkinase PF00069.25 PSC74949.1 - 2e-69 233.9 0.0 2.6e-69 233.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC74949.1 - 5.9e-45 153.6 0.0 8.8e-45 153.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PSC74949.1 - 6.2e-05 22.4 0.2 0.00035 20.0 0.1 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PSC74949.1 - 8.2e-05 22.3 0.1 0.00035 20.2 0.0 1.8 2 0 0 2 2 2 1 RIO1 family YrbL-PhoP_reg PF10707.9 PSC74949.1 - 0.0057 16.2 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL DUF3543 PF12063.8 PSC74949.1 - 0.0094 15.3 0.2 0.032 13.6 0.2 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3543) Pkinase_fungal PF17667.1 PSC74949.1 - 0.12 11.2 0.7 0.55 8.9 0.0 2.1 2 1 0 3 3 3 0 Fungal protein kinase Ephrin_rec_like PF07699.13 PSC74950.1 - 3.4e-45 151.6 157.6 2.6e-09 36.7 6.7 18.4 10 3 9 20 20 20 16 Putative ephrin-receptor like NCD3G PF07562.14 PSC74950.1 - 6.6e-12 45.2 116.3 0.0078 16.2 6.8 15.7 11 4 6 17 17 17 14 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 PSC74950.1 - 0.42 11.1 114.4 0.88 10.0 3.5 17.6 11 5 3 15 15 15 0 TNFR/NGFR cysteine-rich region DUF4684 PF15736.5 PSC74950.1 - 2.7 6.6 6.4 6.3 5.4 6.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) SelR PF01641.18 PSC74951.1 - 4.3e-39 133.3 0.0 5.7e-39 132.9 0.0 1.2 1 0 0 1 1 1 1 SelR domain Myb_DNA-binding PF00249.31 PSC74952.1 - 1.5e-05 25.0 0.0 3.4e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain V_ATPase_I PF01496.19 PSC74952.1 - 5.3 4.8 5.7 8 4.2 5.7 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DEAD PF00270.29 PSC74953.1 - 2.9e-20 72.7 0.0 6.9e-20 71.5 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase WD40 PF00400.32 PSC74953.1 - 9.4e-17 61.1 4.6 0.00025 21.8 0.0 7.3 7 0 0 7 7 7 3 WD domain, G-beta repeat Helicase_C PF00271.31 PSC74953.1 - 4.4e-14 52.8 0.0 9.5e-14 51.7 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Peptidase_M1 PF01433.20 PSC74953.1 - 2.8e-11 43.4 0.3 4.7e-11 42.7 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain JAB PF01398.21 PSC74953.1 - 5.5e-11 42.5 0.0 1.7e-10 40.9 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease ANAPC4_WD40 PF12894.7 PSC74953.1 - 1.7e-05 25.0 0.0 6.3 7.2 0.0 4.9 2 2 4 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain UVR PF02151.19 PSC74953.1 - 0.00097 18.8 0.5 0.00097 18.8 0.5 2.9 3 0 0 3 3 3 1 UvrB/uvrC motif PQQ_3 PF13570.6 PSC74953.1 - 0.032 14.7 2.6 6 7.5 0.1 4.2 3 0 0 3 3 3 0 PQQ-like domain PI3K_1B_p101 PF10486.9 PSC74953.1 - 0.41 8.4 2.9 0.59 7.8 2.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Myosin_head PF00063.21 PSC74954.1 - 4.6e-219 729.0 0.0 7.7e-219 728.3 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 PSC74954.1 - 2.7e-11 42.2 50.0 0.0015 18.2 3.0 6.7 6 0 0 6 6 6 5 IQ calmodulin-binding motif DIL PF01843.19 PSC74954.1 - 5.3e-11 42.7 0.0 5.3e-11 42.7 0.0 3.4 4 0 0 4 4 4 1 DIL domain AAA_22 PF13401.6 PSC74954.1 - 0.031 14.5 3.5 0.035 14.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.12 PSC74954.1 - 0.091 12.3 0.0 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain Myosin_head PF00063.21 PSC74955.1 - 4.6e-219 729.0 0.0 7.7e-219 728.3 0.0 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) IQ PF00612.27 PSC74955.1 - 2.7e-11 42.2 50.0 0.0015 18.2 3.0 6.7 6 0 0 6 6 6 5 IQ calmodulin-binding motif DIL PF01843.19 PSC74955.1 - 5.3e-11 42.7 0.0 5.3e-11 42.7 0.0 3.4 4 0 0 4 4 4 1 DIL domain AAA_22 PF13401.6 PSC74955.1 - 0.031 14.5 3.5 0.035 14.4 0.0 2.9 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.12 PSC74955.1 - 0.091 12.3 0.0 2.1 7.9 0.0 2.4 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain MM_CoA_mutase PF01642.22 PSC74957.1 - 7.2e-233 773.8 0.8 8.4e-233 773.5 0.8 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 PSC74957.1 - 9.5e-14 51.5 2.1 3.6e-13 49.6 0.5 2.4 2 0 0 2 2 2 1 B12 binding domain zf-ANAPC11 PF12861.7 PSC74958.1 - 4.7e-33 113.1 7.5 5.6e-33 112.9 7.5 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 PSC74958.1 - 7e-20 71.1 5.2 1e-19 70.6 5.2 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 PSC74958.1 - 6.1e-08 32.9 8.4 2.7e-07 30.8 8.4 1.9 1 1 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 PSC74958.1 - 1.7e-06 27.9 2.2 2.8e-06 27.2 2.3 1.4 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PSC74958.1 - 8.4e-06 25.5 2.0 8.4e-06 25.5 2.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC74958.1 - 9.3e-06 25.4 1.0 9.3e-06 25.4 1.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC74958.1 - 3.8e-05 23.6 4.6 7e-05 22.8 4.6 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 PSC74958.1 - 0.00011 22.0 1.9 0.0025 17.6 0.4 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 PSC74958.1 - 0.00022 20.9 1.0 0.0051 16.6 0.6 2.1 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 PSC74958.1 - 0.002 17.9 0.9 0.002 17.9 0.9 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 RINGv PF12906.7 PSC74958.1 - 0.0031 17.6 4.0 0.0031 17.6 4.0 2.0 2 0 0 2 2 2 1 RING-variant domain zf-RING-like PF08746.11 PSC74958.1 - 0.0032 17.7 2.9 0.0073 16.6 2.9 1.6 1 0 0 1 1 1 1 RING-like domain zf-C3HC4_4 PF15227.6 PSC74958.1 - 0.0041 17.2 1.5 0.0041 17.2 1.5 1.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 PSC74958.1 - 0.0046 16.5 2.7 0.0046 16.5 2.7 2.4 2 1 1 3 3 3 1 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 PSC74958.1 - 0.0068 16.1 0.3 0.0068 16.1 0.3 2.2 2 0 0 2 2 2 1 RING-like zinc finger zf-Nse PF11789.8 PSC74958.1 - 0.016 15.0 0.2 0.016 15.0 0.2 1.5 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit DUF5318 PF17249.2 PSC74958.1 - 0.04 13.7 0.2 0.25 11.1 0.1 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF5318) DUF2310 PF10071.9 PSC74958.1 - 0.092 12.0 0.4 0.12 11.7 0.4 1.1 1 0 0 1 1 1 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) FANCL_C PF11793.8 PSC74958.1 - 0.31 11.3 8.6 3.3 7.9 8.6 2.5 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.29 PSC74958.1 - 0.56 10.1 6.5 1.6 8.7 6.5 1.8 1 1 0 1 1 1 0 PHD-finger Trehalase PF01204.18 PSC74959.1 - 1.2e-128 430.2 0.0 1.4e-128 429.9 0.0 1.0 1 0 0 1 1 1 1 Trehalase Glyco_hydro_36 PF17167.4 PSC74959.1 - 0.036 12.8 0.0 0.056 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase 36 superfamily, catalytic domain Bac_rhamnosid6H PF17389.2 PSC74959.1 - 0.12 11.6 0.0 0.21 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain K_oxygenase PF13434.6 PSC74960.1 - 2.8e-06 26.7 0.0 0.011 14.9 0.0 2.4 2 0 0 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox PF00070.27 PSC74960.1 - 0.1 13.2 0.8 0.59 10.7 0.1 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PSC74960.1 - 0.11 11.7 1.8 0.68 9.1 0.1 2.2 2 0 0 2 2 2 0 Thi4 family Pyr_redox_2 PF07992.14 PSC74960.1 - 0.11 11.7 9.0 0.085 12.1 3.5 3.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 PSC74960.1 - 0.12 12.6 4.3 2.5 8.4 1.1 2.9 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.6 PSC74960.1 - 0.13 12.7 0.1 0.38 11.2 0.0 1.8 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox_3 PF13738.6 PSC74960.1 - 0.14 11.4 0.0 0.27 10.5 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Aminotran_5 PF00266.19 PSC74961.1 - 2.7e-24 85.8 0.0 1e-16 60.9 0.0 2.2 2 0 0 2 2 2 2 Aminotransferase class-V Choline_kinase PF01633.20 PSC74962.1 - 7e-45 153.2 0.0 1.2e-44 152.4 0.0 1.4 1 0 0 1 1 1 1 Choline/ethanolamine kinase Rep_fac-A_C PF08646.10 PSC74962.1 - 1.5e-24 86.4 0.0 2.4e-24 85.8 0.0 1.3 1 0 0 1 1 1 1 Replication factor-A C terminal domain MRP-L47 PF06984.13 PSC74962.1 - 1.5e-22 79.5 0.2 1.5e-22 79.5 0.2 2.5 3 0 0 3 3 3 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) APH PF01636.23 PSC74962.1 - 2.9e-10 40.5 15.1 4.1e-09 36.7 2.4 2.9 3 1 0 3 3 3 2 Phosphotransferase enzyme family Ribosomal_L29 PF00831.23 PSC74962.1 - 7.9e-09 35.4 0.9 1.6e-08 34.4 0.9 1.5 1 0 0 1 1 1 1 Ribosomal L29 protein DUF3659 PF12396.8 PSC74962.1 - 0.046 13.6 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3659) Heme_oxygenase PF01126.20 PSC74963.1 - 7.9e-06 25.8 0.0 1.1e-05 25.3 0.0 1.2 1 0 0 1 1 1 1 Heme oxygenase PRAI PF00697.22 PSC74964.1 - 2.1e-32 112.5 0.0 2.6e-32 112.2 0.0 1.1 1 0 0 1 1 1 1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase LRR_4 PF12799.7 PSC74965.1 - 6.8e-09 35.9 1.9 0.004 17.5 0.0 4.3 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC74965.1 - 1.6e-06 27.8 1.4 0.053 13.3 0.0 4.6 4 3 0 4 4 4 2 Leucine rich repeat LRR_6 PF13516.6 PSC74965.1 - 4.6e-06 26.3 0.1 1.2 9.4 0.0 4.2 4 0 0 4 4 4 2 Leucine Rich repeat LRR_1 PF00560.33 PSC74965.1 - 8.1e-06 25.7 0.6 4.8 8.1 0.0 4.8 6 0 0 6 6 6 2 Leucine Rich Repeat Ribosomal_L27A PF00828.19 PSC74966.1 - 1.6e-22 80.6 0.4 2e-22 80.2 0.4 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Zip PF02535.22 PSC74968.1 - 0.21 10.8 0.8 0.2 10.8 0.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter SR-25 PF10500.9 PSC74968.1 - 6 6.4 33.1 0.019 14.6 21.4 2.4 2 1 0 2 2 2 0 Nuclear RNA-splicing-associated protein ParA PF10609.9 PSC74969.1 - 1.4e-79 267.0 0.0 1.8e-79 266.7 0.0 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase FeS_assembly_P PF01883.19 PSC74969.1 - 9.9e-18 64.1 0.2 5.4e-17 61.7 0.0 2.3 2 0 0 2 2 2 1 Iron-sulfur cluster assembly protein CbiA PF01656.23 PSC74969.1 - 8.8e-12 45.2 0.0 1.2e-11 44.7 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 PSC74969.1 - 3.4e-11 43.4 0.6 9.7e-10 38.6 0.1 2.2 2 0 0 2 2 2 1 AAA domain DUF971 PF06155.12 PSC74969.1 - 3.5e-08 34.0 0.0 6.8e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF971) MipZ PF09140.11 PSC74969.1 - 3.8e-07 29.7 0.2 9.5e-07 28.4 0.2 1.7 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.18 PSC74969.1 - 0.00013 21.5 0.1 0.00018 21.1 0.1 1.4 1 1 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family VirC1 PF07015.11 PSC74969.1 - 0.00038 19.8 0.1 0.00078 18.8 0.1 1.5 1 0 0 1 1 1 1 VirC1 protein ArsA_ATPase PF02374.15 PSC74969.1 - 0.0011 18.2 0.3 0.0072 15.5 0.0 2.2 2 1 0 2 2 2 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 PSC74969.1 - 0.16 11.5 0.1 0.79 9.2 0.1 2.0 2 0 0 2 2 2 0 Cellulose biosynthesis protein BcsQ CLP1_P PF16575.5 PSC74969.1 - 0.18 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop SBF PF01758.16 PSC74970.1 - 2.3e-34 118.8 16.6 3.8e-34 118.1 16.6 1.4 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 PSC74970.1 - 2.4e-15 56.7 24.2 3.2e-15 56.2 24.2 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) Rieske PF00355.26 PSC74971.1 - 7.5e-17 61.1 0.2 1.5e-16 60.1 0.2 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 PSC74971.1 - 9.8e-14 51.3 0.0 1.6e-13 50.6 0.0 1.4 1 0 0 1 1 1 1 Pheophorbide a oxygenase DUF4407 PF14362.6 PSC74971.1 - 0.11 11.8 4.0 0.21 10.9 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) XhlA PF10779.9 PSC74972.1 - 0.14 12.4 1.0 0.27 11.5 1.0 1.4 1 0 0 1 1 1 0 Haemolysin XhlA PLATZ PF04640.14 PSC74973.1 - 6.6e-24 84.3 0.1 1.6e-23 83.1 0.1 1.7 1 0 0 1 1 1 1 PLATZ transcription factor Dynamin_N PF00350.23 PSC74973.1 - 0.02 14.9 0.0 0.039 14.0 0.0 1.4 1 0 0 1 1 1 0 Dynamin family DUF5600 PF18150.1 PSC74976.1 - 4.5e-31 107.6 0.2 7.6e-31 106.9 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF5600) EHD_N PF16880.5 PSC74976.1 - 1.7e-14 53.4 0.4 3.1e-14 52.6 0.4 1.5 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 PSC74976.1 - 4.7e-13 49.5 0.0 6.3e-12 45.9 0.0 2.1 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 PSC74976.1 - 2.9e-08 33.8 0.0 5.4e-08 32.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase EF-hand_4 PF12763.7 PSC74976.1 - 0.00018 21.4 0.0 0.00042 20.2 0.0 1.6 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 PSC74976.1 - 0.00067 20.1 0.0 0.0019 18.6 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 PSC74976.1 - 0.0014 18.1 0.0 0.04 13.5 0.1 2.8 2 0 0 2 2 2 1 EF hand EF-hand_5 PF13202.6 PSC74976.1 - 0.0053 16.2 0.1 0.026 14.0 0.1 2.1 2 0 0 2 2 2 1 EF hand BDV_P10 PF06515.11 PSC74976.1 - 0.0072 16.4 1.0 0.097 12.7 0.0 3.1 3 0 0 3 3 3 1 Borna disease virus P10 protein EF-hand_6 PF13405.6 PSC74976.1 - 0.017 15.0 0.0 0.23 11.5 0.0 2.9 4 0 0 4 4 4 0 EF-hand domain AIG1 PF04548.16 PSC74976.1 - 0.2 11.0 0.0 1.9 7.8 0.0 2.1 2 0 0 2 2 2 0 AIG1 family Exostosin PF03016.15 PSC74977.1 - 1.4e-45 155.9 0.0 2e-45 155.3 0.0 1.3 1 0 0 1 1 1 1 Exostosin family EGF_2 PF07974.13 PSC74977.1 - 0.027 14.9 17.5 0.027 14.9 17.5 3.6 3 1 0 3 3 3 0 EGF-like domain Kelch_1 PF01344.25 PSC74978.1 - 1.6e-37 126.9 1.4 2.2e-08 33.6 0.0 5.7 5 0 0 5 5 5 5 Kelch motif Bac_DNA_binding PF00216.21 PSC74978.1 - 8.6e-26 90.0 1.1 1.4e-25 89.3 1.1 1.4 1 0 0 1 1 1 1 Bacterial DNA-binding protein Kelch_6 PF13964.6 PSC74978.1 - 2.7e-22 78.2 0.0 0.0026 18.0 0.0 6.5 2 2 4 6 6 6 4 Kelch motif BTB PF00651.31 PSC74978.1 - 4.3e-14 52.7 0.0 8.1e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 PSC74978.1 - 2.3e-12 46.9 0.0 4.5e-12 46.0 0.0 1.4 1 0 0 1 1 1 1 BTB And C-terminal Kelch Kelch_2 PF07646.15 PSC74978.1 - 3.2e-09 36.4 0.0 0.0021 17.9 0.0 5.5 5 0 0 5 5 5 1 Kelch motif Kelch_4 PF13418.6 PSC74978.1 - 1e-06 28.6 4.4 0.04 13.9 0.0 5.7 3 2 3 6 6 6 2 Galactose oxidase, central domain Kelch_5 PF13854.6 PSC74978.1 - 2.5e-05 24.2 0.4 7 6.8 0.0 4.7 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 PSC74978.1 - 0.0064 16.8 19.5 0.01 16.1 0.0 6.4 7 1 1 8 8 8 1 Galactose oxidase, central domain HU-HIG PF18291.1 PSC74978.1 - 0.034 14.2 0.0 0.057 13.5 0.0 1.3 1 0 0 1 1 1 0 HU domain fused to wHTH, Ig, or Glycine-rich motif SNARE_assoc PF09335.11 PSC74979.1 - 2.6e-09 37.6 2.9 1.8e-08 34.9 1.8 2.7 2 1 0 2 2 2 1 SNARE associated Golgi protein HIP1_clath_bdg PF16515.5 PSC74979.1 - 0.3 11.7 0.1 0.3 11.7 0.1 1.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 RRF PF01765.19 PSC74980.1 - 1.6e-58 197.3 0.2 2e-58 196.9 0.2 1.0 1 0 0 1 1 1 1 Ribosome recycling factor Med20 PF08612.11 PSC74981.1 - 6.7e-09 35.4 0.0 1e-08 34.9 0.0 1.3 1 1 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex TatD_DNase PF01026.21 PSC74982.1 - 5.8e-64 215.9 0.0 7.8e-64 215.5 0.0 1.2 1 0 0 1 1 1 1 TatD related DNase DUF533 PF04391.12 PSC74982.1 - 0.046 13.3 6.1 0.087 12.4 6.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF533) DUF2722 PF10846.8 PSC74982.1 - 0.054 12.5 1.6 0.068 12.1 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 PSC74982.1 - 0.24 11.0 5.9 0.31 10.6 5.9 1.1 1 0 0 1 1 1 0 Spt20 family Amidohydro_2 PF04909.14 PSC74982.1 - 0.4 10.4 4.2 2.7 7.7 4.1 2.3 1 1 0 1 1 1 0 Amidohydrolase GILT PF03227.16 PSC74983.1 - 3.3e-21 75.5 0.0 5.4e-21 74.8 0.0 1.3 1 0 0 1 1 1 1 Gamma interferon inducible lysosomal thiol reductase (GILT) Thioredoxin_4 PF13462.6 PSC74983.1 - 0.13 12.4 0.0 0.52 10.5 0.0 1.8 1 1 0 1 1 1 0 Thioredoxin WD40 PF00400.32 PSC74984.1 - 1e-24 86.3 13.6 4.2e-06 27.4 0.1 6.2 6 0 0 6 6 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC74984.1 - 5.8e-15 55.4 0.2 0.00039 20.6 0.0 4.8 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Abhydrolase_1 PF00561.20 PSC74984.1 - 2.3e-13 50.4 0.1 2.4e-10 40.5 0.1 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC74984.1 - 8.8e-05 21.9 0.0 0.00044 19.6 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_4 PF08386.10 PSC74984.1 - 0.00069 19.7 0.0 0.0014 18.7 0.0 1.5 1 0 0 1 1 1 1 TAP-like protein Esterase PF00756.20 PSC74984.1 - 0.004 16.8 0.0 0.0076 15.9 0.0 1.4 1 0 0 1 1 1 1 Putative esterase DLH PF01738.18 PSC74984.1 - 0.0053 16.3 0.0 0.19 11.2 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family Ge1_WD40 PF16529.5 PSC74984.1 - 0.01 14.9 0.4 5.3 5.9 0.0 2.8 2 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 PSC74984.1 - 0.014 15.3 0.1 23 4.8 0.1 3.1 2 1 1 3 3 3 0 Eukaryotic translation initiation factor eIF2A PQQ_2 PF13360.6 PSC74984.1 - 0.024 14.2 0.0 0.044 13.4 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain Peptidase_S9 PF00326.21 PSC74984.1 - 0.027 13.9 0.1 8.3 5.8 0.0 2.8 3 0 0 3 3 3 0 Prolyl oligopeptidase family PQQ PF01011.21 PSC74984.1 - 0.059 13.3 0.2 1.8 8.6 0.1 3.3 4 0 0 4 4 4 0 PQQ enzyme repeat Nup160 PF11715.8 PSC74984.1 - 0.22 10.1 0.1 0.38 9.3 0.1 1.3 1 0 0 1 1 1 0 Nucleoporin Nup120/160 CMAS PF02353.20 PSC74985.1 - 3.6e-39 134.7 0.0 4.8e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 PSC74985.1 - 7.4e-16 58.4 0.0 1.1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC74985.1 - 3.5e-14 53.3 0.0 9.1e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC74985.1 - 1.2e-12 48.3 0.0 2.9e-12 47.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC74985.1 - 6.9e-11 42.8 0.0 1.1e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC74985.1 - 1.3e-08 34.7 0.0 2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PSC74985.1 - 1.2e-06 28.2 0.0 1.9e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.17 PSC74985.1 - 7.1e-06 25.6 0.0 1.1e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase DUF938 PF06080.12 PSC74985.1 - 0.00012 21.9 0.0 0.00019 21.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) tRNA_U5-meth_tr PF05958.11 PSC74985.1 - 0.00022 20.4 0.0 0.0003 19.9 0.0 1.2 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase TehB PF03848.14 PSC74985.1 - 0.00037 20.0 0.0 0.00056 19.4 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.19 PSC74985.1 - 0.0095 15.7 0.0 0.017 14.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 PSC74985.1 - 0.017 16.2 0.0 0.052 14.6 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 PSC74985.1 - 0.023 14.3 0.0 0.12 12.0 0.0 1.9 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 PSC74985.1 - 0.082 13.0 0.0 0.15 12.1 0.0 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Tyr-DNA_phospho PF06087.12 PSC74986.1 - 1.7e-79 267.7 0.0 2.1e-79 267.4 0.0 1.1 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase RRM_1 PF00076.22 PSC74988.1 - 0.00046 19.9 0.0 0.083 12.7 0.0 2.5 2 1 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S15 PF00312.22 PSC74989.1 - 4.2e-26 91.0 0.7 7.6e-26 90.1 0.7 1.4 1 0 0 1 1 1 1 Ribosomal protein S15 TFIIA PF03153.13 PSC74989.1 - 4.2 7.3 29.5 0.17 11.9 22.9 2.0 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FAE1_CUT1_RppA PF08392.12 PSC74991.1 - 2e-121 404.8 0.0 2.7e-121 404.4 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 PSC74991.1 - 4.7e-10 39.5 0.0 3.2e-09 36.8 0.0 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.15 PSC74991.1 - 9.8e-07 28.9 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III PF08545.10 PSC74991.1 - 0.0016 18.2 0.0 0.0044 16.8 0.0 1.6 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_N PF00195.19 PSC74991.1 - 0.0062 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Lipase_3 PF01764.25 PSC74992.1 - 8.9e-09 35.3 0.0 3.5e-07 30.2 0.0 2.4 1 1 1 2 2 2 2 Lipase (class 3) Ank_2 PF12796.7 PSC74993.1 - 7.7e-71 234.7 13.4 3.3e-12 46.8 0.1 10.1 4 2 7 11 11 11 10 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC74993.1 - 3.9e-63 209.0 17.1 1.4e-07 31.9 0.1 12.4 5 3 7 13 13 13 12 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC74993.1 - 1.1e-55 179.0 22.2 0.005 17.2 0.0 17.3 17 0 0 17 17 17 12 Ankyrin repeat Ank_5 PF13857.6 PSC74993.1 - 1.7e-49 165.2 24.6 1.6e-06 28.2 0.3 11.0 7 1 3 10 10 10 9 Ankyrin repeats (many copies) Ank PF00023.30 PSC74993.1 - 8e-40 133.6 36.5 0.0088 16.5 0.2 17.6 17 1 1 18 18 18 12 Ankyrin repeat DUF563 PF04577.14 PSC74993.1 - 7.4e-05 23.0 0.0 0.00015 22.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) HXXSHH PF07586.11 PSC74993.1 - 0.00021 21.0 5.6 0.00071 19.2 5.6 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1552) NTP_transferase PF00483.23 PSC74994.1 - 1.2e-49 169.1 0.0 2.3e-49 168.2 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase HAP2-GCS1 PF10699.9 PSC74994.1 - 1.2e-15 57.2 1.2 3.8e-15 55.6 0.1 2.4 2 0 0 2 2 2 1 Male gamete fusion factor Hexapep PF00132.24 PSC74994.1 - 5.4e-12 44.9 4.6 4e-08 32.7 2.2 3.4 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 PSC74994.1 - 2.3e-09 37.8 0.0 5.4e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 PSC74994.1 - 0.0014 18.3 3.4 0.0014 18.3 3.4 2.3 2 0 0 2 2 2 1 Hexapeptide repeat of succinyl-transferase CTP_transf_3 PF02348.19 PSC74994.1 - 0.042 13.7 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase Na_H_Exchanger PF00999.21 PSC74995.1 - 7.6e-55 186.2 36.1 9.5e-55 185.9 36.1 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family RRM_1 PF00076.22 PSC74995.1 - 1.3e-20 72.9 0.5 2.7e-08 33.5 0.0 3.7 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PSC74995.1 - 0.00011 22.2 1.9 0.0092 16.0 0.0 3.9 5 0 0 5 5 5 1 Nup53/35/40-type RNA recognition motif DUF2062 PF09835.9 PSC74995.1 - 0.54 10.1 16.1 0.2 11.5 3.2 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2062) Bromodomain PF00439.25 PSC74996.1 - 3.1e-19 68.8 0.0 4.7e-19 68.2 0.0 1.3 1 0 0 1 1 1 1 Bromodomain TonB_2 PF13103.6 PSC74996.1 - 0.11 12.8 0.1 0.56 10.5 0.1 2.2 2 0 0 2 2 2 0 TonB C terminal NT5C PF06941.12 PSC74997.1 - 2.3e-13 50.4 0.5 6.7e-13 48.9 0.5 1.7 1 1 0 1 1 1 1 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) TMP-TENI PF02581.17 PSC74997.1 - 0.13 11.6 0.0 0.29 10.4 0.0 1.6 2 0 0 2 2 2 0 Thiamine monophosphate synthase NIF PF03031.18 PSC74997.1 - 0.19 11.5 0.0 0.27 11.0 0.0 1.3 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase DUF4719 PF15843.5 PSC74997.1 - 0.3 11.2 6.6 0.51 10.4 6.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4719) PAP2 PF01569.21 PSC74998.1 - 2.1e-24 85.8 5.7 8e-24 83.9 1.7 2.5 1 1 1 2 2 2 2 PAP2 superfamily PfkB PF00294.24 PSC74999.1 - 9.8e-49 166.3 0.1 9.8e-49 166.3 0.1 1.7 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Abhydrolase_6 PF12697.7 PSC74999.1 - 9.5e-22 78.7 0.9 9.5e-22 78.7 0.9 2.7 3 1 0 3 3 3 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PSC74999.1 - 7.5e-20 71.7 0.1 1.6e-19 70.5 0.1 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC74999.1 - 3.3e-14 52.7 0.0 7.1e-14 51.7 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 PSC74999.1 - 0.039 13.5 0.0 0.094 12.2 0.0 1.6 1 1 0 1 1 1 0 Lipid-droplet associated hydrolase Esterase PF00756.20 PSC74999.1 - 0.079 12.6 0.3 0.32 10.6 0.1 2.0 1 1 1 2 2 2 0 Putative esterase His_Phos_1 PF00300.22 PSC75000.1 - 1e-15 58.0 0.1 1.2e-09 38.2 0.0 2.4 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) CPP1-like PF11833.8 PSC75001.1 - 1.7e-21 76.8 0.0 3.3e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Gly_transf_sug PF04488.15 PSC75001.1 - 1.1e-07 32.4 0.0 2.4e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Caps_synth PF05704.12 PSC75001.1 - 0.034 13.5 0.1 0.054 12.9 0.1 1.2 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein FUSC_2 PF13515.6 PSC75001.1 - 9.6 6.3 9.2 1.4 9.0 4.7 1.9 2 0 0 2 2 2 0 Fusaric acid resistance protein-like Peptidase_M20 PF01546.28 PSC75002.1 - 7.1e-24 84.7 0.4 8e-24 84.5 0.4 1.0 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Peptidase_M28 PF04389.17 PSC75002.1 - 0.081 12.6 0.0 0.081 12.6 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M28 Kinesin PF00225.23 PSC75003.1 - 6.5e-99 331.0 0.0 1.6e-98 329.7 0.0 1.7 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PSC75003.1 - 2.5e-19 69.7 0.0 6e-19 68.4 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding BSP_II PF05432.11 PSC75003.1 - 0.043 13.5 14.8 0.51 10.0 9.1 2.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) TSC22 PF01166.18 PSC75003.1 - 0.11 12.8 0.1 0.11 12.8 0.1 5.9 6 1 1 7 7 7 0 TSC-22/dip/bun family TEX19 PF15553.6 PSC75003.1 - 5.1 7.0 6.6 31 4.5 6.6 2.4 1 0 0 1 1 1 0 Testis-expressed protein 19 PP1c_bdg PF10488.9 PSC75003.1 - 8.2 5.8 15.9 0.54 9.7 8.5 2.7 2 0 0 2 2 2 0 Phosphatase-1 catalytic subunit binding region EzrA PF06160.12 PSC75005.1 - 0.021 13.0 17.0 0.23 9.6 0.5 3.2 2 1 1 3 3 3 0 Septation ring formation regulator, EzrA DUF1664 PF07889.12 PSC75005.1 - 0.53 10.3 18.4 0.24 11.4 3.5 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) AcylCoA_dehyd_C PF12186.8 PSC75005.1 - 1 9.5 5.2 0.89 9.7 0.2 3.0 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase C terminal MPS2 PF17060.5 PSC75005.1 - 1.9 7.7 9.3 0.41 9.9 2.6 2.3 2 0 0 2 2 2 0 Monopolar spindle protein 2 Sulfatase_C PF14707.6 PSC75005.1 - 2.6 8.8 10.6 2.9 8.6 0.7 3.8 3 0 0 3 3 3 0 C-terminal region of aryl-sulfatase zf-met PF12874.7 PSC75006.1 - 4.2e-24 84.2 16.1 1.2e-05 25.6 0.1 5.7 5 0 0 5 5 5 5 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 PSC75006.1 - 1.1e-16 60.6 5.0 0.00044 20.5 0.1 5.3 5 0 0 5 5 5 3 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 PSC75006.1 - 9e-08 32.4 7.8 0.089 13.1 0.1 5.3 5 0 0 5 5 5 3 C2H2 type zinc-finger (2 copies) Dicer_dimer PF03368.14 PSC75006.1 - 0.0069 16.5 0.8 0.049 13.8 0.0 2.8 2 0 0 2 2 2 1 Dicer dimerisation domain zf-U1 PF06220.12 PSC75006.1 - 0.023 14.5 18.1 0.54 10.1 0.0 5.1 5 0 0 5 5 5 0 U1 zinc finger TFIIB_C_1 PF18542.1 PSC75006.1 - 0.72 9.9 8.8 0.93 9.6 0.6 3.8 3 0 0 3 3 3 0 Transcription factor IIB C-terminal module 1 zf-C2H2_4 PF13894.6 PSC75006.1 - 0.88 10.6 16.1 53 5.0 0.1 5.8 5 0 0 5 5 5 0 C2H2-type zinc finger DUF3449 PF11931.8 PSC75006.1 - 9 6.1 13.5 2.5 7.9 0.1 3.6 5 0 0 5 5 5 0 Domain of unknown function (DUF3449) Ephrin_rec_like PF07699.13 PSC75009.1 - 1.8e-31 107.7 136.3 7.4e-09 35.2 8.3 14.2 5 2 10 15 15 15 10 Putative ephrin-receptor like NCD3G PF07562.14 PSC75009.1 - 9.4e-13 47.9 86.2 0.0028 17.6 1.4 11.3 7 3 2 11 11 11 9 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 PSC75009.1 - 0.33 11.4 92.4 0.32 11.4 2.6 14.0 6 5 4 10 10 10 0 TNFR/NGFR cysteine-rich region NEMP PF10225.9 PSC75010.1 - 3.3e-18 66.3 0.0 4.5e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 NEMP family NEMP PF10225.9 PSC75011.1 - 3.3e-18 66.3 0.0 4.6e-18 65.8 0.0 1.1 1 0 0 1 1 1 1 NEMP family Apolipoprotein PF01442.18 PSC75012.1 - 0.0051 16.7 0.1 0.0071 16.2 0.1 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain GOLGA2L5 PF15070.6 PSC75012.1 - 0.026 13.2 0.1 0.032 12.9 0.1 1.0 1 0 0 1 1 1 0 Putative golgin subfamily A member 2-like protein 5 Bacillus_HBL PF05791.11 PSC75012.1 - 0.026 14.3 0.0 0.033 14.0 0.0 1.1 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) TPR_MLP1_2 PF07926.12 PSC75012.1 - 0.042 13.9 0.2 0.069 13.2 0.2 1.3 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF4618 PF15397.6 PSC75012.1 - 0.045 13.2 0.1 0.4 10.1 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) CCDC-167 PF15188.6 PSC75012.1 - 0.1 13.0 0.0 0.44 10.9 0.0 1.8 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 FliT PF05400.13 PSC75012.1 - 0.15 12.9 1.1 0.38 11.6 0.4 1.9 1 1 1 2 2 2 0 Flagellar protein FliT vATP-synt_E PF01991.18 PSC75013.1 - 5.3e-57 192.5 0.7 6.1e-57 192.3 0.7 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit CnrY PF17524.2 PSC75013.1 - 0.59 10.4 2.0 1.2 9.5 0.2 2.3 1 1 2 3 3 3 0 Anti-sigma factor CnrY DEAD PF00270.29 PSC75014.1 - 4.1e-51 173.2 0.0 5.5e-51 172.8 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC75014.1 - 1.1e-22 80.5 0.0 2.1e-22 79.5 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SPRY PF00622.28 PSC75014.1 - 4.6e-22 78.4 0.0 7.8e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 SPRY domain ResIII PF04851.15 PSC75014.1 - 0.0072 16.3 0.0 0.21 11.6 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 PSC75014.1 - 0.048 13.0 0.0 0.076 12.3 0.0 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit MRP-S34 PF16053.5 PSC75015.1 - 3.6e-13 49.3 0.0 3.9e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 Methyltransf_12 PF08242.12 PSC75016.1 - 4.1e-14 53.1 0.1 1.1e-12 48.6 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC75016.1 - 3.6e-13 50.0 0.3 2.8e-12 47.2 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC75016.1 - 1e-12 48.2 5.2 3.6e-12 46.4 0.0 2.8 2 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC75016.1 - 2.1e-09 37.9 0.0 7.9e-09 36.1 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC75016.1 - 2.6e-09 37.1 0.0 5.3e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PSC75016.1 - 0.0069 16.0 0.0 0.015 14.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain F-box-like PF12937.7 PSC75017.1 - 0.00011 22.0 0.1 0.00067 19.5 0.0 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PSC75017.1 - 0.0069 16.2 0.2 0.38 10.7 0.1 2.7 2 0 0 2 2 2 1 F-box domain Pkinase PF00069.25 PSC75018.1 - 6.8e-56 189.5 0.0 8.9e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 PSC75018.1 - 7.3e-25 86.8 11.1 2e-05 25.3 0.0 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 PSC75018.1 - 1.4e-22 80.2 0.0 2.2e-22 79.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase ANAPC4_WD40 PF12894.7 PSC75018.1 - 2.6e-07 30.8 0.0 0.00052 20.3 0.0 3.5 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Kinase-like PF14531.6 PSC75018.1 - 0.00064 19.1 0.0 0.00099 18.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like WD40_like PF17005.5 PSC75018.1 - 0.22 10.8 0.0 0.45 9.8 0.0 1.4 1 0 0 1 1 1 0 WD40-like domain TetR_C_18 PF17923.1 PSC75018.1 - 0.96 10.0 6.9 0.34 11.4 2.8 2.3 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Trp_oprn_chp PF09534.10 PSC75019.1 - 0.01 15.7 2.6 0.013 15.3 2.6 1.3 1 0 0 1 1 1 1 Tryptophan-associated transmembrane protein (Trp_oprn_chp) Phasin PF05597.11 PSC75019.1 - 0.015 15.3 0.1 0.022 14.8 0.1 1.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) HemY_N PF07219.13 PSC75019.1 - 0.033 14.4 1.8 0.056 13.6 1.8 1.3 1 0 0 1 1 1 0 HemY protein N-terminus SelR PF01641.18 PSC75020.1 - 4.9e-44 149.3 0.0 6.7e-44 148.9 0.0 1.2 1 0 0 1 1 1 1 SelR domain HECT_2 PF09814.9 PSC75020.1 - 0.013 14.4 0.0 2.5 6.9 0.0 2.1 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Zn_ribbon_SprT PF17283.2 PSC75020.1 - 0.24 11.3 0.1 0.24 11.3 0.1 2.9 4 0 0 4 4 4 0 SprT-like zinc ribbon domain zf-Mss51 PF13824.6 PSC75020.1 - 0.27 11.4 1.3 0.47 10.6 0.0 2.0 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Methyltransf_21 PF05050.12 PSC75021.1 - 8.2e-19 68.3 0.0 3.4e-10 40.2 0.0 2.5 2 0 0 2 2 2 2 Methyltransferase FkbM domain SAM_MT PF04445.13 PSC75021.1 - 0.00042 19.8 0.0 0.069 12.6 0.0 2.5 2 0 0 2 2 2 2 Putative SAM-dependent methyltransferase Met_10 PF02475.16 PSC75021.1 - 0.0055 16.5 0.1 0.27 10.9 0.0 2.3 2 0 0 2 2 2 1 Met-10+ like-protein Phage_Cox PF10743.9 PSC75021.1 - 0.071 13.2 0.0 4.3 7.5 0.0 2.5 2 0 0 2 2 2 0 Regulatory phage protein cox FUSC PF04632.12 PSC75021.1 - 0.68 8.4 11.8 1.1 7.7 11.8 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Erythro_esteras PF05139.14 PSC75021.1 - 2.5 7.8 8.5 4.9 6.9 8.5 1.4 1 0 0 1 1 1 0 Erythromycin esterase rve PF00665.26 PSC75022.1 - 2.6e-19 69.6 0.0 5.5e-19 68.5 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC75022.1 - 0.0032 17.2 0.0 0.0082 15.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Methyltransf_25 PF13649.6 PSC75024.1 - 0.019 15.6 0.1 0.15 12.7 0.1 2.5 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 PSC75024.1 - 0.097 13.3 0.0 0.93 10.2 0.0 2.8 2 1 0 2 2 2 0 Methyltransferase domain CDP-OH_P_transf PF01066.21 PSC75025.1 - 0.015 16.1 0.3 0.019 15.7 0.3 1.2 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase Metallophos PF00149.28 PSC75026.1 - 3.5e-09 37.5 0.1 2.8e-08 34.5 0.1 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PSC75026.1 - 0.024 14.8 0.0 0.054 13.7 0.0 1.6 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain rve PF00665.26 PSC75027.1 - 1.7e-18 67.0 0.0 4.2e-18 65.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain WW PF00397.26 PSC75027.1 - 3.9e-06 26.8 2.0 0.016 15.3 0.1 2.9 3 0 0 3 3 3 2 WW domain rve_3 PF13683.6 PSC75027.1 - 0.013 15.2 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 Integrase core domain Voltage_CLC PF00654.20 PSC75028.1 - 5.6e-67 226.5 34.1 1.5e-65 221.8 28.6 3.3 1 1 2 3 3 3 2 Voltage gated chloride channel CBS PF00571.28 PSC75028.1 - 0.042 14.3 0.0 0.089 13.3 0.0 1.5 1 0 0 1 1 1 0 CBS domain zf-CCCH_4 PF18044.1 PSC75029.1 - 3.5e-06 26.7 4.3 8.3e-06 25.5 4.3 1.7 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 PSC75029.1 - 1.1e-05 26.1 0.1 3.6e-05 24.4 0.1 1.9 1 0 0 1 1 1 1 Torus domain zf_CCCH_4 PF18345.1 PSC75029.1 - 3.8e-05 23.6 7.1 8.3e-05 22.5 7.1 1.6 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 PSC75029.1 - 0.00025 20.8 3.6 0.00055 19.8 3.6 1.5 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank PF00023.30 PSC75029.1 - 0.00061 20.1 0.8 0.0022 18.3 0.8 2.0 1 0 0 1 1 1 1 Ankyrin repeat DUF1998 PF09369.10 PSC75029.1 - 0.0077 17.0 1.4 0.053 14.3 1.4 2.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Ank_3 PF13606.6 PSC75029.1 - 0.015 15.8 0.2 0.13 12.9 0.1 2.6 2 0 0 2 2 2 0 Ankyrin repeat zf-CCCH_2 PF14608.6 PSC75029.1 - 0.14 12.6 4.4 0.27 11.8 4.4 1.4 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger RR_TM4-6 PF06459.12 PSC75029.1 - 6.5 6.5 12.6 12 5.6 12.6 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Galactosyl_T PF01762.21 PSC75030.1 - 1.2e-35 123.1 0.0 1.7e-35 122.6 0.0 1.2 1 0 0 1 1 1 1 Galactosyltransferase Sel1 PF08238.12 PSC75030.1 - 2.1e-21 75.9 59.3 0.0013 19.3 1.7 11.9 12 0 0 12 12 12 9 Sel1 repeat Fringe PF02434.16 PSC75030.1 - 0.14 11.5 0.0 0.26 10.7 0.0 1.3 1 0 0 1 1 1 0 Fringe-like Rubredoxin PF00301.20 PSC75031.1 - 1.4e-17 63.5 3.7 2e-17 62.9 3.7 1.3 1 0 0 1 1 1 1 Rubredoxin MORN PF02493.20 PSC75032.1 - 2.5e-52 171.7 91.5 1.1e-07 31.3 0.6 14.4 15 0 0 15 15 15 12 MORN repeat Filamin PF00630.19 PSC75032.1 - 1.1e-27 96.8 0.0 3.6e-18 66.3 0.0 2.6 2 0 0 2 2 2 2 Filamin/ABP280 repeat Glyco_hydro_18 PF00704.28 PSC75032.1 - 4.7e-10 39.7 0.0 7.6e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 YtkA PF13115.6 PSC75032.1 - 0.00021 21.8 0.0 0.013 16.1 0.1 2.9 2 0 0 2 2 2 1 YtkA-like Invasin_D3 PF09134.10 PSC75032.1 - 0.025 14.9 0.1 0.025 14.9 0.1 3.3 4 0 0 4 4 4 0 Invasin, domain 3 Myb_DNA-binding PF00249.31 PSC75033.1 - 3.5e-07 30.3 0.0 6.4e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4776 PF16003.5 PSC75033.1 - 1.2 8.1 19.4 1.8 7.5 19.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) TPR_7 PF13176.6 PSC75033.1 - 3.1 8.1 11.7 2.7 8.2 0.0 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat RR_TM4-6 PF06459.12 PSC75033.1 - 9.3 6.0 20.7 18 5.0 20.7 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SQS_PSY PF00494.19 PSC75034.1 - 6.9e-41 140.5 0.0 1.3e-40 139.6 0.0 1.5 1 0 0 1 1 1 1 Squalene/phytoene synthase Thioredoxin PF00085.20 PSC75035.1 - 6.1e-29 100.0 0.0 4.4e-23 81.2 0.0 2.3 2 0 0 2 2 2 2 Thioredoxin DnaJ PF00226.31 PSC75035.1 - 3.4e-26 91.2 2.5 7e-26 90.1 2.5 1.6 1 0 0 1 1 1 1 DnaJ domain Armet PF10208.9 PSC75035.1 - 7.9e-11 42.1 0.0 1.6e-10 41.1 0.0 1.5 1 0 0 1 1 1 1 Degradation arginine-rich protein for mis-folding Thioredoxin_2 PF13098.6 PSC75035.1 - 1.8e-05 25.1 0.0 0.12 12.8 0.0 2.6 2 0 0 2 2 2 2 Thioredoxin-like domain SAP PF02037.27 PSC75035.1 - 0.00027 20.6 0.1 0.00088 19.0 0.1 2.0 1 0 0 1 1 1 1 SAP domain Calsequestrin PF01216.17 PSC75035.1 - 0.00066 18.8 0.0 0.072 12.1 0.0 2.3 3 0 0 3 3 3 1 Calsequestrin Thioredoxin_8 PF13905.6 PSC75035.1 - 0.0086 16.4 0.0 0.46 10.9 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin-like RPT PF13446.6 PSC75035.1 - 0.031 14.2 0.0 0.079 12.9 0.0 1.7 1 0 0 1 1 1 0 A repeated domain in UCH-protein Thioredoxin_6 PF13848.6 PSC75035.1 - 0.068 13.1 0.0 0.43 10.5 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain AhpC-TSA PF00578.21 PSC75035.1 - 0.091 12.7 0.1 0.67 9.9 0.0 2.2 2 1 0 2 2 2 0 AhpC/TSA family HeH PF12949.7 PSC75035.1 - 0.17 11.6 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 HeH/LEM domain Med15 PF09606.10 PSC75035.1 - 4.3 5.9 7.7 6.3 5.3 7.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PseudoU_synth_1 PF01416.20 PSC75036.1 - 4.3e-15 56.1 0.0 3.2e-13 50.1 0.0 2.5 2 0 0 2 2 2 1 tRNA pseudouridine synthase DPBB_1 PF03330.18 PSC75036.1 - 9.6e-05 22.6 0.1 0.00022 21.5 0.1 1.6 1 0 0 1 1 1 1 Lytic transglycolase adh_short PF00106.25 PSC75037.1 - 9.4e-14 51.3 0.0 3.2e-13 49.6 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC75037.1 - 5.8e-10 39.1 0.0 7.5e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PSC75038.1 - 1.4e-13 50.8 0.0 4.6e-13 49.1 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC75038.1 - 9.8e-10 38.4 0.0 1.3e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase ETC_C1_NDUFA5 PF04716.14 PSC75039.1 - 2.5e-13 49.6 0.2 4.1e-13 48.9 0.2 1.4 1 0 0 1 1 1 1 ETC complex I subunit conserved region ExoD PF06055.12 PSC75039.1 - 0.00022 20.6 1.0 0.00087 18.7 1.0 2.1 1 0 0 1 1 1 1 Exopolysaccharide synthesis, ExoD RsbRD_N PF14361.6 PSC75039.1 - 0.15 12.8 0.2 0.39 11.4 0.2 1.6 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain RSB_motif PF16294.5 PSC75040.1 - 6.2e-16 58.5 0.1 6.2e-16 58.5 0.1 4.9 4 1 1 5 5 5 1 RNSP1-SAP18 binding (RSB) motif SAP PF02037.27 PSC75040.1 - 2.1e-13 49.6 1.6 3e-13 49.2 0.1 1.9 2 0 0 2 2 2 1 SAP domain RRM_1 PF00076.22 PSC75040.1 - 0.15 11.9 0.0 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LCM PF04072.14 PSC75041.1 - 4.9e-24 85.3 0.0 7.6e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase DUF2065 PF09838.9 PSC75041.1 - 0.0014 18.6 0.0 0.006 16.6 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2065) Chorismate_bind PF00425.18 PSC75042.1 - 4.2e-89 298.5 0.0 1.5e-87 293.5 0.0 2.2 2 0 0 2 2 2 2 chorismate binding enzyme Anth_synt_I_N PF04715.13 PSC75042.1 - 5.1e-26 91.6 0.0 9.1e-26 90.8 0.0 1.4 1 0 0 1 1 1 1 Anthranilate synthase component I, N terminal region Mito_carr PF00153.27 PSC75043.1 - 3.8e-63 209.4 4.3 1.4e-21 76.2 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Ribosomal_60s PF00428.19 PSC75043.1 - 0.77 10.4 11.4 1.5 9.5 11.4 1.4 1 0 0 1 1 1 0 60s Acidic ribosomal protein HIG_1_N PF04588.13 PSC75044.1 - 5.4e-05 23.3 0.5 7.4e-05 22.9 0.5 1.3 1 0 0 1 1 1 1 Hypoxia induced protein conserved region DnaJ_CXXCXGXG PF00684.19 PSC75045.1 - 0.013 15.9 0.1 0.013 15.9 0.1 2.3 2 0 0 2 2 2 0 DnaJ central domain zf-C4_Topoisom PF01396.19 PSC75045.1 - 0.11 12.4 4.7 2.2 8.2 0.7 2.4 2 0 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger KCNQ2_u3 PF16642.5 PSC75045.1 - 0.24 12.4 0.5 0.24 12.4 0.5 2.9 2 1 1 3 3 3 0 Unstructured region on Potassium channel subunit alpha KvLQT2 TF_Zn_Ribbon PF08271.12 PSC75045.1 - 0.53 9.8 3.7 12 5.5 0.3 3.0 3 0 0 3 3 3 0 TFIIB zinc-binding Anti-TRAP PF15777.5 PSC75045.1 - 1.3 9.1 5.4 10 6.2 5.4 2.3 1 1 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein CRAL_TRIO PF00650.20 PSC75046.1 - 3.8e-33 114.5 0.0 6e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain PsbP PF01789.16 PSC75046.1 - 2.6e-09 37.4 0.1 7.1e-09 36.0 0.1 1.7 1 1 0 1 1 1 1 PsbP CRAL_TRIO_N PF03765.15 PSC75046.1 - 4.5e-07 30.0 0.1 1e-06 28.8 0.1 1.6 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 PSC75046.1 - 0.0034 17.6 0.0 0.006 16.7 0.0 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF2052 PF09747.9 PSC75047.1 - 1.3e-36 126.6 19.5 1.1e-35 123.6 19.5 2.0 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) DUF563 PF04577.14 PSC75047.1 - 1.5e-25 90.6 0.1 1.7e-13 51.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF563) DUF2052 PF09747.9 PSC75048.1 - 9.2e-37 127.1 19.1 8e-36 124.0 19.1 2.0 1 1 0 1 1 1 1 Coiled-coil domain containing protein (DUF2052) DUF563 PF04577.14 PSC75048.1 - 1e-25 91.1 0.1 1.2e-13 51.7 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF563) TMEM208_SND2 PF05620.11 PSC75049.1 - 1.3e-36 125.9 0.2 2.1e-36 125.2 0.2 1.3 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Lipase_GDSL_2 PF13472.6 PSC75050.1 - 1.3e-07 32.2 0.1 3.2e-06 27.7 0.1 3.0 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family rve PF00665.26 PSC75051.1 - 1.9e-18 66.8 0.0 5.1e-18 65.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain DUF563 PF04577.14 PSC75051.1 - 5.9e-16 59.2 0.0 3.2e-15 56.8 0.0 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF563) CBM_2 PF00553.19 PSC75051.1 - 2.2e-07 31.1 0.1 7e-07 29.5 0.1 1.8 1 0 0 1 1 1 1 Cellulose binding domain rve_3 PF13683.6 PSC75051.1 - 0.015 15.1 0.0 0.045 13.5 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain ADH_N PF08240.12 PSC75052.1 - 3.1e-24 85.0 6.7 6.4e-24 83.9 6.7 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 PSC75052.1 - 1.7e-20 73.3 0.1 4.1e-20 72.1 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 PSC75052.1 - 5.7e-08 33.9 0.0 1.2e-07 32.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 PSC75052.1 - 2.7e-05 23.6 0.1 4.5e-05 22.9 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.21 PSC75052.1 - 0.0024 17.2 0.5 0.0049 16.2 0.5 1.4 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_2 PF03446.15 PSC75052.1 - 0.0045 17.2 0.2 0.0098 16.1 0.2 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 PSC75052.1 - 0.094 12.6 0.3 0.19 11.6 0.3 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_7 PF13241.6 PSC75052.1 - 0.097 13.1 0.2 0.48 10.9 0.0 2.1 2 0 0 2 2 2 0 Putative NAD(P)-binding PE PF00934.20 PSC75052.1 - 0.29 11.5 3.8 22 5.5 1.8 2.5 2 0 0 2 2 2 0 PE family MMADHC PF10229.9 PSC75053.1 - 1.1e-25 90.9 0.0 1.6e-25 90.4 0.0 1.2 1 0 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein PAN_4 PF14295.6 PSC75054.1 - 0.00021 21.1 0.6 0.00063 19.6 0.6 1.8 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 PSC75054.1 - 0.025 14.5 0.2 0.041 13.9 0.2 1.3 1 0 0 1 1 1 0 PAN domain DnaJ-X PF14308.6 PSC75055.1 - 1.3e-33 116.2 18.9 8.1e-33 113.6 10.5 3.2 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 PSC75055.1 - 7e-24 83.7 0.2 1.7e-23 82.5 0.2 1.7 1 0 0 1 1 1 1 DnaJ domain ATG_C PF09333.11 PSC75055.1 - 4.6e-08 33.3 0.4 4.6e-08 33.3 0.4 3.3 3 1 0 3 3 3 1 Autophagy-related protein C terminal domain Gag_p17 PF00540.18 PSC75055.1 - 1.8 8.5 5.4 5.6 7.0 5.4 1.9 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) HhH-GPD PF00730.25 PSC75056.1 - 2.8e-07 31.0 0.0 4.9e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein DUF4281 PF14108.6 PSC75057.1 - 1.8e-30 105.9 7.8 1.8e-30 105.9 7.8 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4281) DUF4281 PF14108.6 PSC75058.1 - 2.7e-30 105.3 6.2 2.7e-30 105.3 6.2 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4281) bZIP_1 PF00170.21 PSC75059.1 - 1.3e-14 54.0 16.4 2.2e-14 53.3 16.4 1.4 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PSC75059.1 - 1.1e-08 35.0 14.1 2.5e-08 33.9 14.1 1.6 1 0 0 1 1 1 1 Basic region leucine zipper Sporozoite_P67 PF05642.11 PSC75059.1 - 0.0022 16.2 0.7 0.0041 15.3 0.7 1.4 1 0 0 1 1 1 1 Sporozoite P67 surface antigen bZIP_Maf PF03131.17 PSC75059.1 - 0.0056 17.2 7.6 0.0056 17.2 7.6 2.5 3 0 0 3 3 3 1 bZIP Maf transcription factor PRKG1_interact PF15898.5 PSC75059.1 - 0.022 15.7 4.4 0.022 15.7 4.4 1.9 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain HALZ PF02183.18 PSC75059.1 - 0.024 14.8 2.2 0.041 14.1 2.2 1.3 1 0 0 1 1 1 0 Homeobox associated leucine zipper DUF5101 PF17031.5 PSC75059.1 - 0.09 12.9 1.6 0.22 11.6 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5101) SPT6_acidic PF14632.6 PSC75059.1 - 0.26 11.9 15.5 2.6 8.7 1.9 2.3 2 0 0 2 2 2 0 Acidic N-terminal SPT6 Sigma70_ner PF04546.13 PSC75059.1 - 6.6 6.6 9.8 3.3 7.5 0.7 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region Pectate_lyase_3 PF12708.7 PSC75060.1 - 0.021 14.7 0.0 0.78 9.5 0.0 2.5 1 1 0 1 1 1 0 Pectate lyase superfamily protein Ephrin_rec_like PF07699.13 PSC75061.1 - 5.5e-45 150.9 160.0 1.7e-09 37.3 4.2 19.9 9 7 10 19 19 19 16 Putative ephrin-receptor like Pro_isomerase PF00160.21 PSC75061.1 - 8e-09 36.0 0.0 1.5e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD DUF4684 PF15736.5 PSC75061.1 - 1.2 7.8 3.9 2.3 6.8 3.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) zf-dskA_traR PF01258.17 PSC75061.1 - 1.2 9.2 8.7 2 8.4 0.3 4.9 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger RETICULATA-like PF11891.8 PSC75062.1 - 3.2e-55 186.7 0.0 5.9e-55 185.8 0.0 1.5 1 0 0 1 1 1 1 Protein RETICULATA-related PGAP1 PF07819.13 PSC75062.1 - 0.038 13.7 0.1 0.067 12.9 0.1 1.3 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 PSC75062.1 - 0.28 10.6 0.1 0.69 9.4 0.1 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) LCAT PF02450.15 PSC75062.1 - 0.3 10.2 0.0 0.46 9.6 0.0 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase LicD PF04991.13 PSC75064.1 - 3.7e-06 27.3 0.0 1.2e-05 25.5 0.1 1.7 2 0 0 2 2 2 1 LicD family TFIIA PF03153.13 PSC75067.1 - 0.0011 19.0 27.3 0.0011 19.0 27.3 3.2 1 1 2 3 3 3 2 Transcription factor IIA, alpha/beta subunit CorA PF01544.18 PSC75069.1 - 2.7e-09 36.8 7.8 1.8e-06 27.5 0.3 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 PSC75069.1 - 0.33 11.0 3.1 5.6 7.0 0.4 2.3 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Phasin PF05597.11 PSC75070.1 - 0.00048 20.1 1.5 0.00076 19.5 1.5 1.3 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) Noelin-1 PF12308.8 PSC75070.1 - 0.026 14.5 0.1 0.041 13.9 0.1 1.3 1 0 0 1 1 1 0 Neurogenesis glycoprotein HemY_N PF07219.13 PSC75070.1 - 0.1 12.8 4.2 0.19 12.0 4.2 1.4 1 0 0 1 1 1 0 HemY protein N-terminus SBP PF03110.14 PSC75071.1 - 0.00018 21.7 0.8 0.00036 20.8 0.8 1.5 1 0 0 1 1 1 1 SBP domain SBP PF03110.14 PSC75072.1 - 0.00024 21.4 0.1 0.00046 20.4 0.1 1.5 1 0 0 1 1 1 1 SBP domain UQ_con PF00179.26 PSC75073.1 - 4.8e-17 61.9 0.0 8.2e-17 61.2 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Pkinase PF00069.25 PSC75074.1 - 4.6e-52 177.0 0.0 6.2e-52 176.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC75074.1 - 1.8e-24 86.4 0.0 2.7e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC75074.1 - 1.7e-09 37.4 0.0 3.3e-09 36.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PSC75074.1 - 0.0067 15.2 0.0 0.011 14.6 0.0 1.3 1 1 0 1 1 1 1 Fungal protein kinase CENP-H PF05837.12 PSC75074.1 - 0.68 10.4 3.4 1.9 8.9 3.4 1.7 1 0 0 1 1 1 0 Centromere protein H (CENP-H) FTA4 PF13093.6 PSC75074.1 - 4 7.3 5.9 9 6.1 5.9 1.5 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 RED_N PF07808.13 PSC75075.1 - 2.7e-48 164.6 1.0 2.9e-47 161.2 0.0 2.6 2 1 0 2 2 2 1 RED-like protein N-terminal region RED_C PF07807.11 PSC75075.1 - 4.2e-08 33.6 7.8 1.4e-07 31.9 7.8 1.9 1 1 0 1 1 1 1 RED-like protein C-terminal region WD40 PF00400.32 PSC75076.1 - 4.7e-15 55.7 3.8 0.0065 17.3 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat S4 PF01479.25 PSC75077.1 - 1.1e-09 37.8 0.0 2.3e-09 36.8 0.0 1.5 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 PSC75077.1 - 1.8e-09 38.4 3.8 1.8e-09 38.4 3.8 1.6 2 1 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Stn1_C PF12659.7 PSC75077.1 - 0.024 14.6 0.1 0.045 13.7 0.1 1.5 1 0 0 1 1 1 0 Telomere capping C-terminal wHTH FAE1_CUT1_RppA PF08392.12 PSC75078.1 - 2.8e-108 361.6 0.0 3.4e-108 361.4 0.0 1.0 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein Chal_sti_synt_C PF02797.15 PSC75078.1 - 4.4e-06 26.7 0.0 7.3e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain ACP_syn_III_C PF08541.10 PSC75078.1 - 0.00013 22.1 0.0 0.0013 18.9 0.0 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ACP_syn_III PF08545.10 PSC75078.1 - 0.001 18.9 0.0 0.002 17.9 0.0 1.4 1 0 0 1 1 1 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Chal_sti_synt_N PF00195.19 PSC75078.1 - 0.0032 16.9 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Peptidase_S9_N PF02897.15 PSC75078.1 - 0.12 11.2 0.0 0.24 10.1 0.0 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase, N-terminal beta-propeller domain Mito_carr PF00153.27 PSC75079.1 - 3e-45 152.1 6.2 1.4e-15 56.9 0.3 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein PP2C PF00481.21 PSC75079.1 - 4.1e-34 118.4 0.3 6.1e-34 117.8 0.3 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C FHA PF00498.26 PSC75079.1 - 6.4e-14 52.1 0.2 1.2e-13 51.2 0.2 1.4 1 0 0 1 1 1 1 FHA domain SpoIIE PF07228.12 PSC75079.1 - 6.4e-05 22.9 1.3 0.0033 17.4 0.5 2.4 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Yop-YscD_cpl PF16697.5 PSC75079.1 - 6.6e-05 23.1 0.0 0.00017 21.9 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Ephrin_rec_like PF07699.13 PSC75080.1 - 1.9e-46 155.6 210.9 3e-07 30.1 8.3 23.8 8 7 16 24 24 24 21 Putative ephrin-receptor like CRAL_TRIO PF00650.20 PSC75080.1 - 1.1e-20 74.0 0.0 1.6e-20 73.4 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 PSC75080.1 - 0.0012 19.0 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain TIM PF00121.18 PSC75081.1 - 1.2e-85 286.8 0.0 1.7e-85 286.3 0.0 1.2 1 0 0 1 1 1 1 Triosephosphate isomerase Orn_Arg_deC_N PF02784.16 PSC75081.1 - 4.4e-39 134.3 0.0 7.1e-39 133.7 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Arg_decarb_HB PF17810.1 PSC75081.1 - 6e-13 48.9 0.0 2.5e-12 46.9 0.0 2.0 2 0 0 2 2 2 1 Arginine decarboxylase helical bundle domain Arg_decarbox_C PF17944.1 PSC75081.1 - 4e-05 24.1 0.0 0.00011 22.6 0.0 1.9 1 0 0 1 1 1 1 Arginine decarboxylase C-terminal helical extension p450 PF00067.22 PSC75082.1 - 3.6e-93 312.8 0.0 4.6e-93 312.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Trypan_PARP PF05887.11 PSC75083.1 - 7.4e-05 22.7 18.0 7.4e-05 22.7 18.0 3.5 3 0 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) Podoplanin PF05808.11 PSC75083.1 - 0.0063 16.6 1.8 0.0063 16.6 1.8 1.7 2 0 0 2 2 2 1 Podoplanin FAM176 PF14851.6 PSC75083.1 - 0.18 11.4 0.1 0.33 10.6 0.1 1.4 1 0 0 1 1 1 0 FAM176 family Vwaint PF14624.6 PSC75083.1 - 0.5 10.5 2.0 0.78 9.9 0.7 1.9 2 1 0 2 2 2 0 VWA / Hh protein intein-like UvrB PF12344.8 PSC75083.1 - 1.2 9.1 6.3 2.6 8.0 6.3 1.5 1 0 0 1 1 1 0 Ultra-violet resistance protein B WD40 PF00400.32 PSC75084.1 - 1.9e-10 41.1 8.8 0.0072 17.2 0.1 6.5 6 0 0 6 6 6 3 WD domain, G-beta repeat RB_A PF01858.17 PSC75084.1 - 6.1e-05 22.9 0.0 0.00012 22.0 0.0 1.5 1 1 0 1 1 1 1 Retinoblastoma-associated protein A domain PQQ_3 PF13570.6 PSC75084.1 - 0.00016 22.0 3.9 0.0022 18.4 0.3 4.1 3 0 0 3 3 3 1 PQQ-like domain RB_B PF01857.20 PSC75084.1 - 0.00021 21.3 0.0 0.00033 20.7 0.0 1.3 1 0 0 1 1 1 1 Retinoblastoma-associated protein B domain PQQ PF01011.21 PSC75084.1 - 0.00029 20.6 0.2 0.0015 18.3 0.0 2.3 3 0 0 3 3 3 1 PQQ enzyme repeat PQQ_2 PF13360.6 PSC75084.1 - 0.00067 19.3 0.1 0.0017 18.0 0.1 1.7 1 0 0 1 1 1 1 PQQ-like domain USP7_ICP0_bdg PF12436.8 PSC75085.1 - 3.2e-23 82.3 0.0 2.6e-22 79.3 0.0 2.2 1 1 1 2 2 2 2 ICP0-binding domain of Ubiquitin-specific protease 7 Prok-RING_4 PF14447.6 PSC75085.1 - 0.036 13.9 9.3 0.079 12.8 9.3 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 PSC75085.1 - 0.16 11.9 12.2 0.38 10.7 12.2 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) YukD PF08817.10 PSC75085.1 - 0.31 11.7 5.1 1.1 10.0 0.1 3.7 3 0 0 3 3 3 0 WXG100 protein secretion system (Wss), protein YukD zf-C3HC4_4 PF15227.6 PSC75085.1 - 0.84 9.8 7.7 2.5 8.3 7.7 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 PSC75085.1 - 1.4 9.3 17.6 0.11 12.8 12.6 1.8 2 0 0 2 2 2 0 Ring finger domain DUF4366 PF14283.6 PSC75085.1 - 4.2 7.4 9.4 18 5.3 1.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) zf-RING_5 PF14634.6 PSC75085.1 - 6.8 6.7 16.2 5.2 7.1 12.8 2.5 2 1 0 2 2 2 0 zinc-RING finger domain DUF1824 PF08854.10 PSC75088.1 - 4e-07 30.0 0.0 1.4e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1824) DUF1824 PF08854.10 PSC75089.1 - 3.8e-07 30.1 0.0 1.3e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1824) DUF1824 PF08854.10 PSC75090.1 - 4.1e-07 30.0 0.0 1.4e-06 28.3 0.0 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF1824) DUF938 PF06080.12 PSC75091.1 - 3.9e-65 219.4 0.0 4.4e-65 219.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_25 PF13649.6 PSC75091.1 - 0.0018 19.0 0.0 0.0035 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Pik1 PF11522.8 PSC75092.1 - 0.17 11.8 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Yeast phosphatidylinositol-4-OH kinase Pik1 AC_N PF16214.5 PSC75092.1 - 5.5 6.0 9.5 2.2 7.3 0.2 2.2 2 0 0 2 2 2 0 Adenylyl cyclase N-terminal extracellular and transmembrane region FAM178 PF14816.6 PSC75093.1 - 0.2 10.6 0.6 5.7 5.8 0.0 2.7 3 0 0 3 3 3 0 Family of unknown function, FAM178 Usp PF00582.26 PSC75094.1 - 1.4e-21 77.5 0.1 1.4e-21 77.5 0.1 3.0 2 1 1 3 3 3 1 Universal stress protein family Radial_spoke_3 PF06098.11 PSC75094.1 - 2e-21 76.5 0.0 3.7e-21 75.7 0.0 1.3 1 0 0 1 1 1 1 Radial spoke protein 3 CENP-Q PF13094.6 PSC75094.1 - 2.6 8.2 11.1 0.45 10.7 7.0 1.7 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit SNARE_assoc PF09335.11 PSC75095.1 - 3e-26 92.3 10.6 3e-26 92.3 10.6 2.1 3 0 0 3 3 3 1 SNARE associated Golgi protein IncD PF17628.2 PSC75095.1 - 1.1 9.0 7.0 2.7 7.8 7.0 1.6 1 0 0 1 1 1 0 Inclusion membrane protein D Retrotran_gag_2 PF14223.6 PSC75096.1 - 7.4e-23 80.7 0.0 1.1e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-CCHC_3 PF13917.6 PSC75096.1 - 0.003 17.5 3.7 0.0069 16.3 1.9 2.3 2 0 0 2 2 2 1 Zinc knuckle Retrotrans_gag PF03732.17 PSC75096.1 - 0.0059 16.8 0.0 0.01 16.1 0.0 1.4 1 0 0 1 1 1 1 Retrotransposon gag protein DUF4219 PF13961.6 PSC75096.1 - 0.021 14.5 1.0 0.036 13.8 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4219) zf-C2H2_10 PF16588.5 PSC75096.1 - 0.07 12.9 2.9 0.12 12.1 2.9 1.3 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 PSC75096.1 - 0.26 11.2 4.4 0.47 10.3 4.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_5 PF14787.6 PSC75096.1 - 0.61 9.8 6.0 1.4 8.6 6.0 1.6 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF3093 PF11292.8 PSC75096.1 - 0.75 10.1 4.3 1.5 9.1 4.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3093) CorA PF01544.18 PSC75097.1 - 1.3e-08 34.5 6.5 3.6e-05 23.2 0.2 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 PSC75097.1 - 0.015 15.3 1.9 0.85 9.7 0.1 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus CorA PF01544.18 PSC75098.1 - 1.4e-08 34.5 6.5 3.6e-05 23.2 0.2 2.2 2 0 0 2 2 2 2 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 PSC75098.1 - 0.015 15.3 1.9 0.86 9.6 0.1 2.4 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Formyl_trans_N PF00551.19 PSC75099.1 - 4.2e-53 179.8 0.0 5.2e-53 179.5 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase GRIM-19 PF06212.12 PSC75100.1 - 7.2e-34 116.6 0.0 8.8e-34 116.3 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein Tad PF13400.6 PSC75100.1 - 0.59 10.5 6.4 1.2 9.5 6.3 1.5 1 1 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like GRIM-19 PF06212.12 PSC75101.1 - 4.7e-34 117.2 0.0 5.5e-34 117.0 0.0 1.0 1 0 0 1 1 1 1 GRIM-19 protein Tad PF13400.6 PSC75101.1 - 0.46 10.8 6.5 0.92 9.9 6.4 1.5 1 1 0 1 1 1 0 Putative Flp pilus-assembly TadE/G-like PCRF PF03462.18 PSC75102.1 - 6.8e-60 202.3 0.0 1.2e-59 201.4 0.0 1.4 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 PSC75102.1 - 8.7e-40 135.3 1.3 1.8e-39 134.2 1.3 1.5 1 0 0 1 1 1 1 RF-1 domain AHJR-like PF18743.1 PSC75102.1 - 0.089 12.4 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 REase_AHJR-like ABC_tran_CTD PF16326.5 PSC75102.1 - 5.9 7.2 8.1 0.39 11.0 0.3 2.8 2 1 1 3 3 3 0 ABC transporter C-terminal domain Aminotran_1_2 PF00155.21 PSC75103.1 - 7.3e-88 295.2 0.0 1.1e-87 294.6 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II tRNA-synt_2b PF00587.25 PSC75103.1 - 1.4e-24 87.0 0.0 2.8e-23 82.8 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 PSC75103.1 - 1.6e-18 66.9 0.1 3.1e-18 66.0 0.1 1.5 1 0 0 1 1 1 1 Seryl-tRNA synthetase N-terminal domain ABC_tran_CTD PF16326.5 PSC75103.1 - 0.57 10.5 3.5 7.3 6.9 0.6 2.8 2 0 0 2 2 2 0 ABC transporter C-terminal domain AAA PF00004.29 PSC75104.1 - 3.4e-43 147.2 1.1 7e-43 146.2 0.0 2.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 PSC75104.1 - 5.6e-21 75.3 0.1 1.2e-20 74.1 0.1 1.6 1 0 0 1 1 1 1 Peptidase family M41 AAA_lid_3 PF17862.1 PSC75104.1 - 4e-11 42.5 0.1 4e-11 42.5 0.1 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_33 PF13671.6 PSC75104.1 - 9.6e-05 22.6 1.3 0.00032 20.9 0.0 2.6 2 1 0 2 2 2 1 AAA domain AAA_2 PF07724.14 PSC75104.1 - 0.00015 21.9 0.0 0.0006 20.0 0.0 2.1 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 PSC75104.1 - 0.00021 21.3 1.6 0.00091 19.2 0.2 2.9 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 PSC75104.1 - 0.00027 20.7 0.0 0.002 17.9 0.0 2.3 1 1 1 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PSC75104.1 - 0.00029 21.3 0.4 0.00029 21.3 0.4 3.8 1 1 1 2 2 1 1 AAA ATPase domain TIP49 PF06068.13 PSC75104.1 - 0.001 18.4 0.1 0.0023 17.2 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain IstB_IS21 PF01695.17 PSC75104.1 - 0.0017 18.1 0.1 0.0038 17.0 0.1 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_22 PF13401.6 PSC75104.1 - 0.0095 16.2 7.3 0.013 15.8 0.1 3.6 2 2 1 3 3 3 1 AAA domain Mg_chelatase PF01078.21 PSC75104.1 - 0.021 14.2 0.0 0.044 13.2 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 PSC75104.1 - 0.044 13.5 0.0 0.13 11.9 0.0 1.8 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_18 PF13238.6 PSC75104.1 - 0.11 13.0 0.0 0.11 13.0 0.0 2.4 3 0 0 3 3 1 0 AAA domain RraB PF06877.11 PSC75104.1 - 0.21 12.3 1.8 0.58 10.9 1.8 1.7 1 0 0 1 1 1 0 Regulator of ribonuclease activity B AAA_28 PF13521.6 PSC75104.1 - 0.26 11.5 0.0 0.26 11.5 0.0 3.1 3 0 0 3 3 2 0 AAA domain Flavokinase PF01687.17 PSC75106.1 - 1e-31 109.5 0.0 1.8e-31 108.7 0.0 1.4 1 0 0 1 1 1 1 Riboflavin kinase Methyltransf_23 PF13489.6 PSC75106.1 - 7e-12 45.5 0.0 1e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC75106.1 - 2.3e-11 44.3 0.0 4.2e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC75106.1 - 2.6e-11 44.0 0.0 4.4e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC75106.1 - 5.4e-08 32.8 0.0 7.7e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC75106.1 - 1.8e-07 31.8 0.0 3.5e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC75106.1 - 0.021 14.2 0.0 0.03 13.7 0.0 1.1 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DREV PF05219.12 PSC75106.1 - 0.2 10.7 0.0 0.3 10.2 0.0 1.1 1 0 0 1 1 1 0 DREV methyltransferase Ephrin_rec_like PF07699.13 PSC75107.1 - 3.2e-45 151.6 187.2 7.2e-09 35.3 8.8 20.5 10 6 11 22 22 22 16 Putative ephrin-receptor like NCD3G PF07562.14 PSC75107.1 - 3.9e-18 65.2 120.1 0.0023 17.9 8.5 16.6 12 5 1 17 17 17 11 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 PSC75107.1 - 0.073 13.5 0.3 0.073 13.5 0.3 18.8 13 4 3 17 17 17 0 TNFR/NGFR cysteine-rich region PAN_4 PF14295.6 PSC75109.1 - 5.4e-06 26.2 16.4 0.00043 20.1 1.0 2.8 2 1 0 2 2 2 2 PAN domain SfsA_N PF17746.1 PSC75109.1 - 0.0028 17.8 0.0 0.0065 16.6 0.0 1.5 1 0 0 1 1 1 1 SfsA N-terminal OB domain PAN_1 PF00024.26 PSC75109.1 - 0.0032 17.4 6.8 0.008 16.1 0.8 2.4 2 1 0 2 2 2 2 PAN domain MANEC PF07502.14 PSC75109.1 - 0.7 10.2 8.0 5.6 7.3 1.4 2.3 2 0 0 2 2 2 0 MANEC domain GTP_EFTU PF00009.27 PSC75110.1 - 3.6e-59 199.6 0.0 5.3e-59 199.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 PSC75110.1 - 2.4e-39 133.9 0.0 5.5e-39 132.7 0.0 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 PSC75110.1 - 4.1e-33 113.3 0.0 8.4e-33 112.3 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 PSC75110.1 - 3.7e-28 97.4 0.1 1.1e-27 95.9 0.1 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PSC75110.1 - 1.4e-15 57.4 0.0 3.6e-15 56.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 PSC75110.1 - 1.1e-06 28.5 0.0 2.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 PSC75110.1 - 0.02 15.0 0.0 0.043 13.9 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase CSD PF00313.22 PSC75111.1 - 2.8e-26 91.1 0.2 4e-26 90.7 0.2 1.2 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 PSC75111.1 - 0.00024 20.7 0.1 0.00058 19.5 0.1 1.6 1 0 0 1 1 1 1 Ribonuclease B OB domain CSD PF00313.22 PSC75112.1 - 2.8e-26 91.1 0.2 4.1e-26 90.6 0.2 1.3 1 0 0 1 1 1 1 'Cold-shock' DNA-binding domain OB_RNB PF08206.11 PSC75112.1 - 0.00059 19.5 0.1 0.00059 19.5 0.1 1.9 2 0 0 2 2 2 1 Ribonuclease B OB domain DUF1168 PF06658.12 PSC75113.1 - 4.1e-26 91.4 22.1 1.1e-25 90.0 22.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1168) rve PF00665.26 PSC75113.1 - 1.2e-18 67.4 0.0 2.4e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC75113.1 - 0.0082 15.9 0.0 0.024 14.4 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Ephrin_rec_like PF07699.13 PSC75114.1 - 9.6e-77 252.6 312.9 1.9e-07 30.7 6.3 33.8 10 6 23 34 34 34 31 Putative ephrin-receptor like NCD3G PF07562.14 PSC75114.1 - 1e-21 76.7 209.9 0.0017 18.3 8.2 28.0 16 6 16 34 34 34 24 Nine Cysteines Domain of family 3 GPCR Exostosin PF03016.15 PSC75115.1 - 3.7e-85 285.8 0.0 4.5e-43 147.6 0.0 2.2 2 0 0 2 2 2 2 Exostosin family Brix PF04427.18 PSC75116.1 - 4.4e-31 108.5 0.0 5.9e-31 108.1 0.0 1.2 1 0 0 1 1 1 1 Brix domain SelP_N PF04592.14 PSC75117.1 - 7 6.0 11.0 14 5.0 11.0 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SelP_N PF04592.14 PSC75118.1 - 7 6.0 11.0 14 5.0 11.0 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region SelP_N PF04592.14 PSC75119.1 - 7 6.0 11.0 14 5.0 11.0 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region BNR PF02012.20 PSC75120.1 - 4.2e-05 22.9 4.0 0.12 12.5 0.4 3.0 2 0 0 2 2 2 2 BNR/Asp-box repeat DUF4185 PF13810.6 PSC75120.1 - 0.0044 16.3 5.0 0.19 10.9 0.4 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF4185) Sortilin-Vps10 PF15902.5 PSC75120.1 - 0.16 10.7 0.0 0.23 10.2 0.0 1.2 1 0 0 1 1 1 0 Sortilin, neurotensin receptor 3, TFIID_NTD2 PF04494.15 PSC75121.1 - 5.2e-31 107.6 0.0 9.6e-31 106.7 0.0 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain HAD_2 PF13419.6 PSC75121.1 - 4.3e-18 66.0 0.0 8e-18 65.1 0.0 1.5 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PSC75121.1 - 1.9e-14 54.5 0.1 1.9e-14 54.5 0.1 2.3 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PSC75121.1 - 1.6e-07 31.2 0.1 6.1e-07 29.4 0.1 2.1 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 PSC75121.1 - 0.00028 21.3 0.0 0.0013 19.2 0.0 2.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase LisH PF08513.11 PSC75121.1 - 0.0031 17.4 0.0 0.008 16.1 0.0 1.7 1 0 0 1 1 1 1 LisH NIF PF03031.18 PSC75121.1 - 0.0035 17.1 0.0 0.012 15.4 0.0 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Hydrolase_6 PF13344.6 PSC75121.1 - 0.05 13.7 0.1 9.7 6.4 0.0 2.7 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PSC75122.1 - 5.4e-19 69.0 0.0 9.8e-19 68.1 0.0 1.4 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PSC75122.1 - 1e-15 58.6 0.1 2.4e-15 57.4 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PSC75122.1 - 7.4e-08 32.3 0.1 1.7e-07 31.2 0.1 1.7 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 PSC75122.1 - 6e-05 23.5 0.0 0.00018 21.9 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NIF PF03031.18 PSC75122.1 - 0.00042 20.1 0.0 0.0022 17.8 0.0 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Hydrolase_6 PF13344.6 PSC75122.1 - 0.0074 16.4 0.2 3.3 7.9 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase Orn_Arg_deC_N PF02784.16 PSC75123.1 - 1.7e-74 250.4 0.0 2.4e-74 249.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain WD40 PF00400.32 PSC75123.1 - 4.2e-39 131.8 13.0 1.7e-07 31.8 0.2 6.8 6 0 0 6 6 6 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 PSC75123.1 - 1.2e-30 106.4 0.0 1.9e-30 105.7 0.0 1.3 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 PSC75123.1 - 1.1e-12 48.1 0.0 0.12 12.7 0.0 5.3 2 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Orn_DAP_Arg_deC PF00278.22 PSC75123.1 - 7.8e-09 35.7 0.0 2.9e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ge1_WD40 PF16529.5 PSC75123.1 - 0.00013 21.1 0.4 0.31 9.9 0.1 2.8 2 2 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PSC75123.1 - 0.0052 15.5 0.9 0.28 9.8 0.1 2.8 3 1 1 4 4 4 1 Nucleoporin Nup120/160 LisH PF08513.11 PSC75123.1 - 0.0054 16.6 0.0 0.014 15.4 0.0 1.7 1 0 0 1 1 1 1 LisH Nbas_N PF15492.6 PSC75123.1 - 0.016 14.6 0.1 0.16 11.2 0.0 2.5 2 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal TFIIS_M PF07500.14 PSC75124.1 - 1.2e-21 77.3 0.0 1.2e-21 77.3 0.0 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain LSM PF01423.22 PSC75125.1 - 8.5e-14 51.0 0.1 9.3e-14 50.9 0.1 1.0 1 0 0 1 1 1 1 LSM domain Spc7 PF08317.11 PSC75126.1 - 4e-12 45.6 7.8 6.7e-12 44.9 7.8 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Atg14 PF10186.9 PSC75126.1 - 0.14 11.2 11.8 0.23 10.5 11.8 1.2 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 UPF0564 PF10595.9 PSC75126.1 - 6.8 5.6 14.4 14 4.6 14.4 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 DLH PF01738.18 PSC75127.1 - 6.2e-12 45.5 0.2 2e-11 43.9 0.2 1.8 2 0 0 2 2 2 1 Dienelactone hydrolase family Bestrophin PF01062.21 PSC75127.1 - 1.7e-07 30.9 5.9 6.6e-05 22.4 0.4 2.8 2 1 1 3 3 3 2 Bestrophin, RFP-TM, chloride channel rve PF00665.26 PSC75127.1 - 0.055 13.7 2.8 0.086 13.0 0.0 2.7 3 0 0 3 3 3 0 Integrase core domain Integrase_H2C2 PF17921.1 PSC75127.1 - 0.15 12.2 1.0 1.1 9.4 0.0 2.4 2 0 0 2 2 2 0 Integrase zinc binding domain RWP-RK PF02042.15 PSC75128.1 - 1.9e-09 37.4 0.1 3.4e-09 36.5 0.1 1.5 1 0 0 1 1 1 1 RWP-RK domain DUF2786 PF10979.8 PSC75128.1 - 0.43 10.5 8.2 5.7 6.9 0.1 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2786) CLP1_P PF16575.5 PSC75129.1 - 4.7e-67 225.4 0.0 6.9e-67 224.9 0.0 1.3 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 PSC75129.1 - 8.2e-28 97.2 0.0 1.5e-27 96.4 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 PSC75129.1 - 5.4e-25 87.4 0.0 8.9e-25 86.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor Pirin_C_2 PF17954.1 PSC75129.1 - 0.043 14.0 0.0 0.086 13.0 0.0 1.5 1 0 0 1 1 1 0 Quercetinase C-terminal cupin domain MMR_HSR1 PF01926.23 PSC75129.1 - 0.062 13.4 0.0 0.2 11.7 0.0 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PSC75129.1 - 0.14 12.1 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 RsgA GTPase bZIP_1 PF00170.21 PSC75130.1 - 5.2e-10 39.3 14.4 5.2e-10 39.3 14.4 2.3 2 1 1 3 3 2 1 bZIP transcription factor bZIP_2 PF07716.15 PSC75130.1 - 0.00012 22.1 11.7 0.00012 22.1 11.7 3.5 3 0 0 3 3 2 1 Basic region leucine zipper DUF4164 PF13747.6 PSC75130.1 - 0.00074 19.8 11.4 0.0032 17.7 11.4 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4164) FAM76 PF16046.5 PSC75130.1 - 0.001 18.5 12.7 0.0021 17.5 12.7 1.4 1 0 0 1 1 1 1 FAM76 protein DUF3584 PF12128.8 PSC75130.1 - 0.0019 15.8 3.9 0.0019 15.8 3.9 3.0 3 0 0 3 3 2 1 Protein of unknown function (DUF3584) bZIP_Maf PF03131.17 PSC75130.1 - 0.0036 17.8 16.4 0.0036 17.8 16.4 3.6 3 1 0 3 3 2 1 bZIP Maf transcription factor Spc7 PF08317.11 PSC75130.1 - 0.0039 16.1 3.3 0.0039 16.1 3.3 2.8 3 0 0 3 3 2 1 Spc7 kinetochore protein ABC_tran_CTD PF16326.5 PSC75130.1 - 0.0067 16.7 5.3 0.0067 16.7 5.3 3.6 3 0 0 3 3 2 1 ABC transporter C-terminal domain YlqD PF11068.8 PSC75130.1 - 0.0095 16.3 4.5 0.0095 16.3 4.5 3.2 3 0 0 3 3 2 1 YlqD protein APG6_N PF17675.1 PSC75130.1 - 0.022 15.3 10.3 0.022 15.3 10.3 3.3 3 0 0 3 3 3 0 Apg6 coiled-coil region Med15 PF09606.10 PSC75130.1 - 0.043 12.5 43.3 0.064 11.9 43.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF812 PF05667.11 PSC75130.1 - 0.1 11.5 24.4 0.17 10.7 24.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) SPX PF03105.19 PSC75130.1 - 0.21 11.5 17.8 0.36 10.7 17.8 1.3 1 0 0 1 1 1 0 SPX domain TFIIA PF03153.13 PSC75130.1 - 0.31 11.0 53.4 0.7 9.8 53.4 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_23 PF13476.6 PSC75130.1 - 0.69 10.4 13.4 1.7 9.1 3.5 2.2 2 0 0 2 2 2 0 AAA domain Peptidase_S64 PF08192.11 PSC75130.1 - 3.4 6.0 11.5 5.7 5.3 11.5 1.3 1 0 0 1 1 1 0 Peptidase family S64 Spt20 PF12090.8 PSC75130.1 - 8.2 6.0 43.8 0.06 13.0 28.4 2.4 2 0 0 2 2 2 0 Spt20 family Myb_Cef PF11831.8 PSC75131.1 - 1.2e-49 169.0 3.2 1.2e-49 169.0 3.2 9.2 7 2 3 10 10 10 1 pre-mRNA splicing factor component TPH PF13868.6 PSC75131.1 - 7.2e-42 143.2 152.3 7.2e-42 143.2 152.3 8.3 7 2 1 8 8 8 1 Trichohyalin-plectin-homology domain Myb_DNA-binding PF00249.31 PSC75131.1 - 3.3e-21 75.2 4.4 8.4e-11 41.9 1.2 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC75131.1 - 7.2e-19 67.8 2.7 8.1e-12 45.2 2.0 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF1296 PF06972.11 PSC75131.1 - 6e-17 61.5 0.1 6e-17 61.5 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1296) Myb_Cef PF11831.8 PSC75132.1 - 1.2e-49 169.0 3.2 1.2e-49 169.0 3.2 9.2 7 2 2 9 9 9 1 pre-mRNA splicing factor component TPH PF13868.6 PSC75132.1 - 7.2e-42 143.2 152.3 7.2e-42 143.2 152.3 8.3 7 2 1 8 8 8 1 Trichohyalin-plectin-homology domain Myb_DNA-binding PF00249.31 PSC75132.1 - 3.3e-21 75.2 4.4 8.4e-11 41.9 1.2 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC75132.1 - 7.3e-19 67.8 2.7 8.1e-12 45.2 2.0 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain DUF1296 PF06972.11 PSC75132.1 - 6e-17 61.5 0.1 6e-17 61.5 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1296) polyprenyl_synt PF00348.17 PSC75133.1 - 7.5e-93 310.3 0.1 9.6e-93 309.9 0.1 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Ephrin_rec_like PF07699.13 PSC75134.1 - 1.2e-13 50.6 97.4 0.00017 21.3 2.6 13.7 9 4 2 12 12 12 9 Putative ephrin-receptor like NUDIX PF00293.28 PSC75135.1 - 8.6e-19 67.9 0.0 1.4e-18 67.2 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain 2OG-FeII_Oxy_3 PF13640.6 PSC75136.1 - 3.3e-10 40.7 0.0 5.3e-10 40.1 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 PSC75136.1 - 0.15 12.6 0.0 0.27 11.7 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.6 PSC75137.1 - 1.6e-10 41.7 0.0 2.8e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 PSC75137.1 - 1.4e-05 25.5 3.7 2.5e-05 24.7 3.7 1.5 1 0 0 1 1 1 1 ShK domain-like Pkinase PF00069.25 PSC75138.1 - 2.3e-54 184.6 0.0 4.4e-54 183.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Exostosin PF03016.15 PSC75138.1 - 5.8e-38 130.8 0.0 9.8e-38 130.0 0.0 1.4 1 0 0 1 1 1 1 Exostosin family Pkinase_Tyr PF07714.17 PSC75138.1 - 1.2e-33 116.5 0.0 2.1e-33 115.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ATP-synt_DE_N PF02823.16 PSC75138.1 - 2.2e-15 56.3 0.1 4.3e-15 55.4 0.1 1.5 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain ARGLU PF15346.6 PSC75138.1 - 2.6e-11 43.6 36.7 2.6e-11 43.6 36.7 2.5 1 1 1 2 2 2 1 Arginine and glutamate-rich 1 Kinase-like PF14531.6 PSC75138.1 - 1.5e-07 31.0 0.0 2.6e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 PSC75138.1 - 0.012 14.5 0.0 0.022 13.7 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 PSC75138.1 - 2.4 6.9 19.8 8.3 5.1 19.8 1.8 1 1 0 1 1 1 0 Fungal protein kinase Corona_nucleoca PF00937.18 PSC75138.1 - 2.9 6.8 10.4 5.5 5.9 10.4 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein Neur_chan_memb PF02932.16 PSC75139.1 - 5.1 7.1 5.0 9.5 6.2 5.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Glyco_hydro_32N PF00251.20 PSC75140.1 - 3.6e-45 154.8 0.0 3e-32 112.4 0.0 2.1 2 0 0 2 2 2 2 Glycosyl hydrolases family 32 N-terminal domain Glyco_hydro_32C PF08244.12 PSC75140.1 - 7.3e-09 35.8 0.0 4e-08 33.4 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolases family 32 C terminal adh_short PF00106.25 PSC75141.1 - 9.6e-23 80.7 0.0 7.2e-22 77.8 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC75141.1 - 1.1e-12 48.0 0.0 4.2e-12 46.1 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC75141.1 - 2.7e-06 27.4 1.2 4.2e-05 23.6 0.1 2.4 2 0 0 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.19 PSC75141.1 - 0.12 11.7 0.1 0.19 11.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 PSC75142.1 - 1.1e-22 80.5 0.0 7.7e-22 77.7 0.0 2.2 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC75142.1 - 1.2e-12 47.9 0.0 4.5e-12 46.0 0.0 2.0 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC75142.1 - 3e-06 27.3 1.2 4.4e-05 23.5 0.1 2.4 2 0 0 2 2 2 1 KR domain 2-Hacid_dh_C PF02826.19 PSC75142.1 - 0.13 11.6 0.1 0.2 11.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain PGAP1 PF07819.13 PSC75143.1 - 2.3e-13 50.4 0.0 2.3e-05 24.2 0.0 2.1 2 0 0 2 2 2 2 PGAP1-like protein Palm_thioest PF02089.15 PSC75143.1 - 1e-07 32.1 0.0 0.013 15.4 0.0 2.2 2 0 0 2 2 2 2 Palmitoyl protein thioesterase DUF676 PF05057.14 PSC75143.1 - 3.5e-07 30.0 0.0 0.017 14.7 0.0 2.1 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Abhydrolase_3 PF07859.13 PSC75143.1 - 2.9e-06 27.3 0.1 0.03 14.2 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PSC75143.1 - 1.4e-05 25.8 19.9 0.0071 17.0 2.5 2.7 1 1 1 3 3 3 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 PSC75143.1 - 3e-05 23.6 0.2 0.1 12.0 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 PSC75143.1 - 0.00054 19.3 0.1 0.86 8.8 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 LCAT PF02450.15 PSC75143.1 - 0.00057 19.2 0.0 0.59 9.2 0.0 2.1 2 0 0 2 2 2 2 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 PSC75143.1 - 0.0052 16.6 0.9 2.9 7.7 0.1 2.2 2 0 0 2 2 2 2 Lipase (class 3) LIDHydrolase PF10230.9 PSC75143.1 - 0.016 14.8 0.2 4.7 6.7 0.0 2.1 2 0 0 2 2 2 0 Lipid-droplet associated hydrolase Thioesterase PF00975.20 PSC75143.1 - 0.1 12.7 1.6 8.1 6.5 0.1 2.3 2 0 0 2 2 2 0 Thioesterase domain Chlorophyllase2 PF12740.7 PSC75143.1 - 0.22 10.4 0.2 14 4.5 0.0 2.1 2 0 0 2 2 2 0 Chlorophyllase enzyme Ephrin_rec_like PF07699.13 PSC75144.1 - 9.8e-46 153.3 186.1 1.7e-09 37.2 7.7 20.4 10 6 11 22 22 22 16 Putative ephrin-receptor like NCD3G PF07562.14 PSC75144.1 - 9.5e-18 63.9 119.8 0.0023 17.9 8.5 16.7 11 5 4 18 18 18 13 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 PSC75144.1 - 0.1 13.0 0.2 0.1 13.0 0.2 18.8 13 4 4 17 17 17 0 TNFR/NGFR cysteine-rich region DSPc PF00782.20 PSC75145.1 - 2.7e-20 72.5 0.0 8.3e-20 71.0 0.0 1.8 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain zf-FPG_IleRS PF06827.14 PSC75145.1 - 0.0007 19.4 2.6 0.78 9.7 0.2 2.6 2 0 0 2 2 2 2 Zinc finger found in FPG and IleRS SMP PF04927.12 PSC75145.1 - 0.014 15.9 1.9 0.014 15.9 1.9 1.8 2 0 0 2 2 2 0 Seed maturation protein Y_phosphatase PF00102.27 PSC75145.1 - 0.04 13.5 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein-tyrosine phosphatase zf-RRN7 PF11781.8 PSC75145.1 - 0.098 12.4 3.0 4 7.2 0.2 2.4 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 Med3 PF11593.8 PSC75145.1 - 2.3 7.3 12.2 3.1 6.9 12.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF2967 PF11179.8 PSC75145.1 - 3.7 5.5 7.9 5 5.1 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Thioredoxin PF00085.20 PSC75146.1 - 7.7e-31 106.1 0.0 1e-30 105.7 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 PSC75146.1 - 9e-08 32.5 0.1 9.3e-07 29.3 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PSC75146.1 - 2.9e-06 27.5 0.0 0.00042 20.6 0.0 2.2 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 PSC75146.1 - 7.7e-06 25.7 0.0 1.1e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin TraF PF13728.6 PSC75146.1 - 0.0013 18.6 0.0 0.0019 18.0 0.0 1.2 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_3 PF13192.6 PSC75146.1 - 0.0042 17.1 0.0 0.006 16.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_7 PF13899.6 PSC75146.1 - 0.0049 17.0 0.0 0.0089 16.2 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like HyaE PF07449.11 PSC75146.1 - 0.017 15.1 0.0 0.027 14.4 0.0 1.4 1 1 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Redoxin PF08534.10 PSC75146.1 - 0.024 14.3 0.0 0.14 11.9 0.0 1.8 1 1 1 2 2 2 0 Redoxin Thioredoxin_5 PF13743.6 PSC75146.1 - 0.035 13.8 0.1 1.1 8.9 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin OST3_OST6 PF04756.13 PSC75146.1 - 0.046 13.1 0.0 0.052 12.9 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family TPR_19 PF14559.6 PSC75147.1 - 5.8e-24 84.4 38.7 9.6e-05 22.8 0.9 10.2 5 2 3 10 10 10 6 Tetratricopeptide repeat TPR_16 PF13432.6 PSC75147.1 - 1.4e-17 64.0 53.5 0.0015 19.1 0.0 11.9 7 4 5 12 12 11 10 Tetratricopeptide repeat TPR_2 PF07719.17 PSC75147.1 - 1.5e-16 59.1 34.5 0.12 12.6 0.8 13.4 14 0 0 14 14 12 4 Tetratricopeptide repeat TPR_8 PF13181.6 PSC75147.1 - 5.9e-16 57.3 3.7 0.004 17.3 0.0 11.6 12 0 0 12 12 12 1 Tetratricopeptide repeat TPR_12 PF13424.6 PSC75147.1 - 1.4e-14 54.1 46.9 0.00029 21.1 0.0 10.8 8 2 3 11 11 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 PSC75147.1 - 5.8e-14 51.2 19.0 0.0048 16.7 0.3 11.1 12 0 0 12 12 12 2 Tetratricopeptide repeat TPR_14 PF13428.6 PSC75147.1 - 1.3e-13 50.5 62.1 0.048 14.5 0.2 14.5 11 4 5 16 16 13 8 Tetratricopeptide repeat TPR_11 PF13414.6 PSC75147.1 - 1.3e-11 44.0 22.6 0.0001 21.9 0.0 8.1 9 1 0 9 9 8 3 TPR repeat TPR_7 PF13176.6 PSC75147.1 - 1.9e-10 40.0 21.5 0.15 12.1 0.0 11.3 12 0 0 12 12 11 2 Tetratricopeptide repeat TPR_17 PF13431.6 PSC75147.1 - 8.1e-10 38.4 21.5 0.0081 16.5 0.0 11.5 14 0 0 14 14 14 2 Tetratricopeptide repeat TPR_15 PF13429.6 PSC75147.1 - 1.2e-08 34.5 15.1 0.0041 16.4 3.9 4.8 2 2 0 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 PSC75147.1 - 1.8e-08 34.5 37.5 1.7 9.5 0.1 13.0 15 0 0 15 15 12 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PSC75147.1 - 6.1e-06 26.4 19.4 0.12 12.6 0.2 8.0 8 1 1 9 9 8 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 PSC75147.1 - 0.0005 20.2 1.4 0.0005 20.2 1.4 10.2 5 3 6 11 11 11 2 Tetratricopeptide repeat TPR_20 PF14561.6 PSC75147.1 - 0.001 19.4 24.6 0.35 11.2 0.1 7.7 5 2 4 9 9 8 2 Tetratricopeptide repeat ANAPC5 PF12862.7 PSC75147.1 - 0.0066 16.5 0.2 11 6.1 0.0 4.7 4 1 1 5 5 4 0 Anaphase-promoting complex subunit 5 PknG_TPR PF16918.5 PSC75147.1 - 0.0078 15.0 9.7 0.38 9.4 0.0 4.4 4 1 0 5 5 5 1 Protein kinase G tetratricopeptide repeat MAS20 PF02064.15 PSC75147.1 - 0.025 14.7 7.1 0.065 13.3 0.0 3.6 3 0 0 3 3 3 0 MAS20 protein import receptor HrpB1_HrpK PF09613.10 PSC75147.1 - 0.05 13.2 5.3 1.2 8.8 0.0 4.8 4 1 0 5 5 5 0 Bacterial type III secretion protein (HrpB1_HrpK) Pro_dh-DNA_bdg PF14850.6 PSC75147.1 - 0.053 14.0 0.0 0.27 11.8 0.0 2.2 1 0 0 1 1 1 0 DNA-binding domain of Proline dehydrogenase HEAT_2 PF13646.6 PSC75147.1 - 0.21 12.0 8.0 4.9 7.6 0.2 4.7 3 2 0 4 4 4 0 HEAT repeats Vpu PF00558.19 PSC75147.1 - 0.25 11.1 0.0 0.25 11.1 0.0 2.2 2 0 0 2 2 1 0 Vpu protein T3SSipB PF16535.5 PSC75147.1 - 0.28 11.7 1.7 21 5.5 0.1 2.8 2 0 0 2 2 2 0 Type III cell invasion protein SipB BHD_2 PF10404.9 PSC75147.1 - 4.2 8.4 7.2 15 6.6 0.9 3.2 3 0 0 3 3 2 0 Rad4 beta-hairpin domain 2 RBFA PF02033.18 PSC75148.1 - 2.1e-23 82.7 0.1 3.1e-23 82.2 0.1 1.2 1 0 0 1 1 1 1 Ribosome-binding factor A FoP_duplication PF13865.6 PSC75148.1 - 1.2 9.8 8.9 0.35 11.5 5.9 1.7 2 0 0 2 2 2 0 C-terminal duplication domain of Friend of PRMT1 Aldo_ket_red PF00248.21 PSC75149.1 - 2e-40 138.8 0.0 4.1e-40 137.8 0.0 1.4 1 0 0 1 1 1 1 Aldo/keto reductase family ShK PF01549.24 PSC75149.1 - 5.9e-06 26.7 8.8 1.1e-05 25.9 8.8 1.5 1 0 0 1 1 1 1 ShK domain-like DDHD PF02862.17 PSC75149.1 - 0.02 15.0 0.7 0.036 14.2 0.7 1.5 1 0 0 1 1 1 0 DDHD domain DUF4746 PF15928.5 PSC75149.1 - 0.64 9.4 5.8 0.98 8.8 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) DUF4407 PF14362.6 PSC75149.1 - 1.5 8.1 13.3 3.6 6.9 13.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nop53 PF07767.11 PSC75149.1 - 1.6 8.1 19.4 2.5 7.4 19.4 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Pex14_N PF04695.13 PSC75149.1 - 4.1 8.0 21.3 19 5.9 21.1 2.1 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PAT1 PF09770.9 PSC75149.1 - 4.3 5.5 18.6 6 5.0 18.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 PSC75149.1 - 4.4 7.0 13.0 6.9 6.4 13.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ndc1_Nup PF09531.10 PSC75149.1 - 4.5 5.8 7.2 7.1 5.2 7.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Rieske PF00355.26 PSC75151.1 - 6.4e-20 70.9 0.0 1.2e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain PaO PF08417.12 PSC75151.1 - 1.4e-16 60.4 0.0 2.7e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Pheophorbide a oxygenase DUF983 PF06170.12 PSC75151.1 - 0.034 14.5 0.3 0.091 13.2 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF983) CDP-OH_P_transf PF01066.21 PSC75152.1 - 1.6e-14 54.4 0.3 1.6e-14 54.4 0.3 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Ribosomal_60s PF00428.19 PSC75152.1 - 0.2 12.3 19.1 0.58 10.8 19.1 1.8 1 0 0 1 1 1 0 60s Acidic ribosomal protein Spt20 PF12090.8 PSC75153.1 - 1.5 8.4 5.9 2.4 7.7 5.9 1.2 1 0 0 1 1 1 0 Spt20 family Med3 PF11593.8 PSC75153.1 - 5.4 6.1 7.7 8.7 5.4 7.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal bZIP_1 PF00170.21 PSC75154.1 - 7.4e-07 29.2 13.6 1.6e-06 28.1 13.6 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PSC75154.1 - 0.00011 22.2 15.8 0.00011 22.2 15.8 2.0 2 0 0 2 2 2 1 Basic region leucine zipper TFIIA PF03153.13 PSC75154.1 - 0.015 15.3 19.8 0.037 14.0 19.9 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit YabA PF06156.13 PSC75154.1 - 0.044 14.4 0.3 0.12 13.0 0.3 1.8 1 0 0 1 1 1 0 Initiation control protein YabA TrbC PF04956.13 PSC75154.1 - 1.2 9.3 3.5 3.4 8.0 3.5 1.7 1 0 0 1 1 1 0 TrbC/VIRB2 family Rsm22 PF09243.10 PSC75157.1 - 2.7e-58 197.4 0.0 2.3e-29 102.6 0.0 3.5 3 1 0 3 3 3 3 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 PSC75157.1 - 0.00096 19.0 0.0 0.0019 18.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain SPX PF03105.19 PSC75157.1 - 0.027 14.4 8.0 0.062 13.2 8.0 1.7 1 0 0 1 1 1 0 SPX domain Macoilin PF09726.9 PSC75157.1 - 0.46 9.0 13.1 0.73 8.3 13.1 1.2 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 PSC75157.1 - 0.53 9.1 13.1 0.8 8.5 13.1 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain BUD22 PF09073.10 PSC75157.1 - 3.2 7.0 19.8 4 6.7 16.8 2.4 2 0 0 2 2 2 0 BUD22 Peroxin-3 PF04882.12 PSC75157.1 - 3.7 6.4 6.2 5.8 5.8 6.2 1.3 1 0 0 1 1 1 0 Peroxin-3 DUF4614 PF15391.6 PSC75157.1 - 7.9 6.4 20.0 16 5.4 20.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Steroid_dh PF02544.16 PSC75158.1 - 2.7e-48 163.8 0.4 5.3e-48 162.8 0.4 1.5 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Ribosomal_S27 PF01599.19 PSC75158.1 - 9.9e-26 89.6 1.9 1.7e-25 88.9 1.9 1.4 1 0 0 1 1 1 1 Ribosomal protein S27a ubiquitin PF00240.23 PSC75158.1 - 1.2e-16 60.2 0.0 2e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family DUF1295 PF06966.12 PSC75158.1 - 3.7e-05 23.4 1.1 3.7e-05 23.4 1.1 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1295) Rad60-SLD PF11976.8 PSC75158.1 - 8.5e-05 22.3 0.0 0.00018 21.3 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_5 PF18037.1 PSC75158.1 - 0.028 14.8 0.9 0.039 14.3 0.0 1.6 2 0 0 2 2 2 0 Ubiquitin-like domain TBK1_ULD PF18396.1 PSC75158.1 - 0.18 11.7 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 TANK binding kinase 1 ubiquitin-like domain TPT PF03151.16 PSC75159.1 - 2.7e-15 56.5 9.3 3.4e-15 56.1 9.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 PSC75159.1 - 0.018 14.3 11.3 0.052 12.8 11.3 1.6 1 1 0 1 1 1 0 UAA transporter family CPBP PF02517.16 PSC75159.1 - 7.5 7.0 10.1 0.11 12.9 1.7 2.2 1 1 1 2 2 2 0 CPBP intramembrane metalloprotease TPT PF03151.16 PSC75160.1 - 2.6e-15 56.5 9.3 3.5e-15 56.1 9.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 PSC75160.1 - 0.017 14.3 11.3 0.053 12.7 11.3 1.7 1 1 0 1 1 1 0 UAA transporter family CRAL_TRIO PF00650.20 PSC75161.1 - 1.6e-15 57.2 0.0 2.7e-15 56.5 0.0 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 PSC75161.1 - 0.007 16.5 0.0 0.018 15.2 0.0 1.6 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain HAD PF12710.7 PSC75161.1 - 0.39 11.1 0.1 0.39 11.1 0.1 3.8 4 0 0 4 4 4 0 haloacid dehalogenase-like hydrolase zf-rbx1 PF12678.7 PSC75162.1 - 9.1e-12 45.1 3.5 9.1e-12 45.1 3.5 1.8 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 PSC75162.1 - 9.4e-11 41.9 7.2 9.4e-11 41.9 7.2 2.2 2 1 0 2 2 1 1 Ring finger domain zf-ANAPC11 PF12861.7 PSC75162.1 - 7.8e-08 32.3 1.4 1.4e-07 31.5 1.4 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 PSC75162.1 - 1.2e-07 31.5 7.6 1.2e-07 31.5 7.6 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC75162.1 - 1.1e-06 28.4 6.6 1.1e-06 28.4 6.6 2.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC75162.1 - 1.5e-06 28.1 3.9 1.5e-06 28.1 3.9 2.3 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 PSC75162.1 - 2.4e-06 27.4 4.1 2.4e-06 27.4 4.1 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 PSC75162.1 - 0.00011 21.8 2.4 0.00011 21.8 2.4 2.7 3 0 0 3 3 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 PSC75162.1 - 0.00044 20.0 3.6 0.00044 20.0 3.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 PSC75162.1 - 0.016 15.0 1.3 1.5 8.7 0.1 2.3 2 0 0 2 2 2 0 Rad50 zinc hook motif FANCL_C PF11793.8 PSC75162.1 - 0.16 12.2 9.7 1.8 8.8 9.7 2.6 1 1 0 1 1 1 0 FANCL C-terminal domain Ras PF00071.22 PSC75163.1 - 7.4e-53 178.5 0.1 1.1e-52 177.9 0.1 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PSC75163.1 - 4e-29 101.3 0.0 6.9e-29 100.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PSC75163.1 - 3.8e-16 59.0 0.0 6e-16 58.4 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family bZIP_1 PF00170.21 PSC75163.1 - 3e-07 30.4 12.7 6.6e-07 29.3 12.7 1.5 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PSC75163.1 - 5.7e-05 23.1 16.5 0.00024 21.1 16.5 2.1 1 0 0 1 1 1 1 Basic region leucine zipper MMR_HSR1 PF01926.23 PSC75163.1 - 0.00016 21.7 0.0 0.00035 20.6 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PSC75163.1 - 0.00034 20.6 0.2 0.12 12.3 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 PSC75163.1 - 0.00099 18.6 0.0 0.0021 17.5 0.0 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 PSC75163.1 - 0.013 15.0 0.0 0.034 13.7 0.0 1.6 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 PSC75163.1 - 0.016 14.6 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 PSC75163.1 - 0.037 14.4 0.0 0.037 14.4 0.0 3.8 3 2 0 3 3 2 0 AAA ATPase domain AAA_29 PF13555.6 PSC75163.1 - 0.063 13.0 0.1 0.2 11.4 0.1 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 PSC75163.1 - 0.16 12.4 0.8 2.5 8.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain YabA PF06156.13 PSC75163.1 - 0.5 11.0 4.1 1.5 9.5 4.1 1.8 1 0 0 1 1 1 0 Initiation control protein YabA YfhO PF09586.10 PSC75163.1 - 0.54 8.4 1.4 0.75 8.0 1.4 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO TFIIA PF03153.13 PSC75163.1 - 6.2 6.7 20.9 12 5.8 21.0 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Mnd1 PF03962.15 PSC75165.1 - 1.3e-26 92.7 0.3 2.8e-26 91.6 0.3 1.6 1 0 0 1 1 1 1 Mnd1 HTH domain LZ3wCH PF18517.1 PSC75165.1 - 2.6e-10 40.2 1.5 6.5e-10 39.0 1.5 1.8 1 0 0 1 1 1 1 Leucine zipper with capping helix domain Tropomyosin_1 PF12718.7 PSC75165.1 - 0.0039 17.4 7.7 0.0075 16.4 7.7 1.5 1 0 0 1 1 1 1 Tropomyosin like Seryl_tRNA_N PF02403.22 PSC75165.1 - 0.015 15.5 7.2 0.015 15.5 7.2 2.4 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Methyltransf_7 PF03492.15 PSC75165.1 - 0.023 13.9 0.3 0.03 13.6 0.3 1.2 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase GntR PF00392.21 PSC75165.1 - 0.053 13.2 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family Lzipper-MIP1 PF14389.6 PSC75165.1 - 0.067 13.5 7.3 0.19 12.1 7.3 1.7 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 TrmB PF01978.19 PSC75165.1 - 0.091 12.7 0.0 0.23 11.4 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Atg14 PF10186.9 PSC75165.1 - 0.13 11.3 3.9 0.16 11.0 3.9 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Lebercilin PF15619.6 PSC75165.1 - 0.32 10.6 12.4 0.5 10.0 11.1 2.0 1 1 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease PKcGMP_CC PF16808.5 PSC75165.1 - 1 9.3 5.4 1.5 8.7 1.2 2.7 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF2203 PF09969.9 PSC75165.1 - 2 9.2 8.1 9.9 6.9 5.4 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF4795 PF16043.5 PSC75165.1 - 3.8 7.1 12.6 6.4 6.3 4.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) DUF4140 PF13600.6 PSC75165.1 - 4.2 7.9 11.1 1.3 9.5 1.3 2.6 1 1 1 2 2 2 0 N-terminal domain of unknown function (DUF4140) Spc24 PF08286.11 PSC75165.1 - 5.7 7.2 10.6 1e+02 3.2 9.8 3.1 2 1 0 2 2 2 0 Spc24 subunit of Ndc80 AAA_23 PF13476.6 PSC75165.1 - 7.4 7.0 10.1 2.6 8.5 7.1 1.7 1 1 1 2 2 2 0 AAA domain OmpH PF03938.14 PSC75165.1 - 8.2 6.8 23.3 0.72 10.2 16.8 2.3 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) DUF4407 PF14362.6 PSC75165.1 - 9.3 5.5 10.0 21 4.3 10.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DivIC PF04977.15 PSC75165.1 - 9.8 6.0 14.5 0.95 9.3 3.8 2.8 2 1 1 3 3 3 0 Septum formation initiator DUF1998 PF09369.10 PSC75167.1 - 2.9e-24 85.6 0.9 1.2e-23 83.6 0.9 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) HCNGP PF07818.13 PSC75167.1 - 1.8e-23 83.0 0.2 7.7e-23 81.0 0.0 2.1 2 0 0 2 2 2 1 HCNGP-like protein DEAD PF00270.29 PSC75167.1 - 1.1e-21 77.4 0.0 1.8e-21 76.7 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC75167.1 - 5.6e-12 46.0 0.0 1e-11 45.1 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain BNR PF02012.20 PSC75167.1 - 0.00018 21.0 9.1 4.5 7.7 0.0 5.8 6 0 0 6 6 6 1 BNR/Asp-box repeat ResIII PF04851.15 PSC75167.1 - 0.0029 17.6 0.0 0.005 16.8 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CDT1 PF08839.11 PSC75167.1 - 0.11 12.8 0.0 0.49 10.7 0.0 2.0 2 0 0 2 2 2 0 DNA replication factor CDT1 like Sortilin-Vps10 PF15902.5 PSC75167.1 - 0.16 10.7 0.0 38 2.9 0.0 2.9 2 1 1 3 3 3 0 Sortilin, neurotensin receptor 3, CHCH PF06747.13 PSC75168.1 - 3.7e-08 33.3 3.7 5.3e-08 32.8 3.7 1.3 1 0 0 1 1 1 1 CHCH domain Cmc1 PF08583.10 PSC75168.1 - 0.0002 21.3 1.1 0.017 15.1 0.0 2.2 1 1 1 2 2 2 2 Cytochrome c oxidase biogenesis protein Cmc1 like Pet191_N PF10203.9 PSC75168.1 - 0.0048 17.2 4.2 0.011 16.1 4.2 1.6 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 COX17 PF05051.13 PSC75168.1 - 0.01 16.2 3.8 0.053 13.9 3.7 2.1 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) CX9C PF16860.5 PSC75168.1 - 0.25 11.4 1.7 0.41 10.7 1.7 1.4 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Exostosin PF03016.15 PSC75169.1 - 3.5e-26 92.1 0.3 6.7e-26 91.2 0.3 1.4 1 0 0 1 1 1 1 Exostosin family EGF_2 PF07974.13 PSC75169.1 - 0.097 13.1 50.1 0.32 11.4 6.1 4.8 4 1 0 4 4 4 0 EGF-like domain Ribosomal_60s PF00428.19 PSC75170.1 - 4.4e-05 24.0 12.5 9.6e-05 22.9 12.5 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein NOA36 PF06524.12 PSC75170.1 - 0.019 14.3 2.4 0.027 13.8 2.4 1.2 1 0 0 1 1 1 0 NOA36 protein RNA_pol_3_Rpc31 PF11705.8 PSC75170.1 - 0.027 14.7 5.2 0.04 14.2 5.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF3381 PF11861.8 PSC75170.1 - 0.15 11.8 5.9 0.19 11.5 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DNA_pol_phi PF04931.13 PSC75170.1 - 0.31 9.1 7.8 0.32 9.0 7.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi CENP-B_dimeris PF09026.10 PSC75170.1 - 0.32 11.4 6.4 0.48 10.8 6.4 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CDC45 PF02724.14 PSC75170.1 - 2.2 6.5 9.3 2.2 6.5 9.3 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF4637 PF15470.6 PSC75170.1 - 8.5 6.1 11.1 13 5.5 11.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Kinesin PF00225.23 PSC75171.1 - 4.5e-97 325.0 0.0 6.9e-97 324.3 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PSC75171.1 - 2.5e-44 150.8 0.0 1.3e-43 148.5 0.0 2.1 2 0 0 2 2 2 1 Microtubule binding MyTH4 PF00784.17 PSC75171.1 - 4.7e-27 94.6 0.3 1.1e-26 93.4 0.3 1.7 1 0 0 1 1 1 1 MyTH4 domain Rhodanese PF00581.20 PSC75171.1 - 2.3e-21 76.3 0.0 2e-12 47.6 0.0 2.9 2 0 0 2 2 2 2 Rhodanese-like domain FERM_M PF00373.18 PSC75171.1 - 3.6e-17 62.9 0.2 1.5e-16 60.8 0.2 2.2 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 PSC75171.1 - 1.8e-07 31.0 0.0 3.7e-07 30.0 0.0 1.6 1 0 0 1 1 1 1 FERM N-terminal domain KNOX2 PF03791.13 PSC75171.1 - 0.12 11.9 0.2 0.42 10.2 0.2 2.0 1 0 0 1 1 1 0 KNOX2 domain Sec8_exocyst PF04048.14 PSC75171.1 - 0.27 11.1 0.0 0.27 11.1 0.0 3.0 3 0 0 3 3 3 0 Sec8 exocyst complex component specific domain DUF4407 PF14362.6 PSC75171.1 - 2.4 7.4 29.5 15 4.8 25.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4407) FliJ PF02050.16 PSC75171.1 - 5 7.4 21.3 0.56 10.4 0.5 3.5 3 0 0 3 3 3 0 Flagellar FliJ protein SBP PF03110.14 PSC75172.1 - 8.6e-29 99.7 8.5 1.5e-28 98.9 8.5 1.4 1 0 0 1 1 1 1 SBP domain rve PF00665.26 PSC75172.1 - 2.3e-18 66.5 0.0 5.2e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC75172.1 - 0.015 15.1 0.0 0.046 13.5 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Seryl_tRNA_N PF02403.22 PSC75172.1 - 0.19 12.0 1.7 2.9 8.1 0.5 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain SBP PF03110.14 PSC75173.1 - 8.6e-29 99.7 8.5 1.5e-28 98.9 8.5 1.4 1 0 0 1 1 1 1 SBP domain rve PF00665.26 PSC75173.1 - 2.6e-18 66.4 0.0 5.2e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Seryl_tRNA_N PF02403.22 PSC75173.1 - 0.014 15.6 1.4 0.25 11.6 0.4 2.5 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain rve_3 PF13683.6 PSC75173.1 - 0.015 15.1 0.0 0.046 13.5 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain Aminotran_1_2 PF00155.21 PSC75174.1 - 3.6e-48 164.6 0.0 6.3e-48 163.8 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II ALMT PF11744.8 PSC75174.1 - 1.4e-10 40.6 9.8 3.1e-10 39.5 9.8 1.6 1 1 0 1 1 1 1 Aluminium activated malate transporter FUSC_2 PF13515.6 PSC75174.1 - 1.1e-08 35.2 9.4 2.8e-08 33.9 9.4 1.8 1 0 0 1 1 1 1 Fusaric acid resistance protein-like FUSC PF04632.12 PSC75174.1 - 2.4e-07 29.7 20.3 2.4e-07 29.7 20.3 3.8 2 1 0 3 3 3 1 Fusaric acid resistance protein family Beta_elim_lyase PF01212.21 PSC75174.1 - 0.037 13.3 0.0 0.097 11.9 0.0 1.7 1 0 0 1 1 1 0 Beta-eliminating lyase ArAE_2 PF10334.9 PSC75174.1 - 0.042 13.7 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Aromatic acid exporter family member 2 zf-C3HC4_2 PF13923.6 PSC75175.1 - 2e-10 40.3 8.1 3.5e-10 39.5 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC75175.1 - 2e-08 34.0 9.7 3.4e-08 33.2 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC75175.1 - 8.3e-08 32.4 12.9 1.5e-07 31.7 12.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 PSC75175.1 - 8.8e-05 22.3 12.5 0.00014 21.6 12.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC75175.1 - 0.00027 20.9 5.4 0.00064 19.7 5.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 PSC75175.1 - 0.00034 20.8 9.7 0.00093 19.4 9.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain TFIIA PF03153.13 PSC75175.1 - 0.0005 20.2 5.4 0.0005 20.2 5.4 1.7 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit zf-RING_5 PF14634.6 PSC75175.1 - 0.00053 19.9 8.4 0.00098 19.0 8.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain SNARE_assoc PF09335.11 PSC75175.1 - 0.002 18.6 0.4 0.0074 16.8 0.4 2.0 1 0 0 1 1 1 1 SNARE associated Golgi protein Prok-RING_4 PF14447.6 PSC75175.1 - 0.0082 16.0 9.6 0.017 15.0 9.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 PSC75175.1 - 0.012 15.7 4.8 0.025 14.6 4.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 PSC75175.1 - 0.023 14.8 7.0 0.047 13.8 7.0 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 PSC75175.1 - 0.027 14.4 5.3 0.049 13.5 5.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 PSC75175.1 - 0.043 13.6 5.5 0.087 12.6 5.5 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-Nse PF11789.8 PSC75175.1 - 0.26 11.1 5.4 0.57 10.0 5.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.6 PSC75175.1 - 0.33 10.8 11.3 0.38 10.6 9.6 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 PSC75175.1 - 0.39 11.1 9.9 0.75 10.2 9.9 1.5 1 0 0 1 1 1 0 RING-like domain zf-RING_10 PF16685.5 PSC75175.1 - 1.4 9.1 8.5 2.6 8.3 8.5 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-UDP PF14569.6 PSC75175.1 - 2.1 8.5 7.2 4.5 7.5 7.2 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger PsbQ PF05757.11 PSC75175.1 - 5.1 6.8 8.8 14 5.3 8.8 1.7 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) zf-C3HC4_2 PF13923.6 PSC75176.1 - 1.8e-10 40.5 8.1 3.6e-10 39.5 8.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC75176.1 - 1.7e-08 34.2 9.7 3.5e-08 33.2 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC75176.1 - 7.6e-08 32.6 12.9 1.5e-07 31.6 12.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 PSC75176.1 - 0.00014 21.6 12.5 0.00014 21.6 12.5 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC75176.1 - 0.00024 21.0 5.4 0.00065 19.7 5.4 1.8 1 0 0 1 1 1 1 RING-type zinc-finger TFIIA PF03153.13 PSC75176.1 - 0.00051 20.2 5.4 0.00051 20.2 5.4 1.7 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit zf-rbx1 PF12678.7 PSC75176.1 - 0.00077 19.7 14.0 0.00094 19.4 9.7 2.6 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PSC75176.1 - 0.00099 19.0 8.4 0.00099 19.0 8.4 1.7 2 0 0 2 2 1 1 zinc-RING finger domain SNARE_assoc PF09335.11 PSC75176.1 - 0.0021 18.6 0.4 0.0075 16.7 0.4 2.0 1 0 0 1 1 1 1 SNARE associated Golgi protein Prok-RING_4 PF14447.6 PSC75176.1 - 0.0066 16.3 9.6 0.017 15.0 9.6 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 PSC75176.1 - 0.026 14.4 5.3 0.05 13.5 5.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 PSC75176.1 - 0.042 13.6 5.5 0.089 12.6 5.5 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 PSC75176.1 - 0.047 13.7 7.1 0.025 14.6 4.8 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.8 PSC75176.1 - 0.25 11.2 5.4 0.58 10.0 5.4 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 PSC75176.1 - 0.36 11.2 9.9 0.76 10.1 9.9 1.6 1 0 0 1 1 1 0 RING-like domain zf-C3HC4_4 PF15227.6 PSC75176.1 - 0.38 11.0 11.4 0.048 13.8 7.0 1.9 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 PSC75176.1 - 1.2 9.4 8.5 2.6 8.2 8.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 PSC75176.1 - 1.5 8.7 14.5 0.39 10.6 9.6 2.5 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 PSC75176.1 - 1.8 8.8 7.2 4.6 7.4 7.2 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger PsbQ PF05757.11 PSC75176.1 - 5.1 6.8 8.8 14 5.3 8.8 1.7 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Ndc1_Nup PF09531.10 PSC75176.1 - 9 4.9 5.2 15 4.1 5.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NTP_transferase PF00483.23 PSC75177.1 - 9.1e-65 218.7 0.0 1.6e-64 217.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Las1 PF04031.13 PSC75177.1 - 3.1e-37 128.0 0.4 1.1e-36 126.3 0.4 2.0 1 0 0 1 1 1 1 Las1-like Hexapep PF00132.24 PSC75177.1 - 0.00097 18.8 7.4 0.01 15.6 0.5 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) AfsA PF03756.13 PSC75177.1 - 0.38 10.8 3.3 2.7 8.0 1.1 2.6 2 0 0 2 2 2 0 A-factor biosynthesis hotdog domain NTP_transferase PF00483.23 PSC75178.1 - 9.5e-65 218.6 0.0 1.7e-64 217.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Las1 PF04031.13 PSC75178.1 - 6.2e-46 156.3 2.0 2e-45 154.7 2.0 1.9 1 0 0 1 1 1 1 Las1-like Hexapep PF00132.24 PSC75178.1 - 0.001 18.7 7.4 0.01 15.5 0.5 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) AfsA PF03756.13 PSC75178.1 - 0.4 10.7 3.3 2.8 7.9 1.1 2.6 2 0 0 2 2 2 0 A-factor biosynthesis hotdog domain NTP_transferase PF00483.23 PSC75179.1 - 9.5e-65 218.6 0.0 1.7e-64 217.8 0.0 1.4 1 0 0 1 1 1 1 Nucleotidyl transferase Las1 PF04031.13 PSC75179.1 - 5.5e-46 156.5 2.0 2e-45 154.7 2.0 2.0 1 0 0 1 1 1 1 Las1-like Hexapep PF00132.24 PSC75179.1 - 0.001 18.7 7.4 0.01 15.5 0.5 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) AfsA PF03756.13 PSC75179.1 - 0.4 10.7 3.3 2.8 7.9 1.1 2.6 2 0 0 2 2 2 0 A-factor biosynthesis hotdog domain Glyco_transf_64 PF09258.10 PSC75180.1 - 4.1e-42 144.1 0.0 9.4e-42 143.0 0.0 1.5 1 1 0 1 1 1 1 Glycosyl transferase family 64 domain CM_2 PF01817.21 PSC75180.1 - 0.34 11.3 1.8 2 8.8 0.0 2.5 2 0 0 2 2 2 0 Chorismate mutase type II FG-GAP PF01839.23 PSC75181.1 - 4.9e-09 36.1 11.2 0.032 14.4 0.0 4.4 4 0 0 4 4 4 3 FG-GAP repeat VCBS PF13517.6 PSC75181.1 - 6.3e-07 29.9 0.1 0.46 11.1 0.0 4.0 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Peptidase_M1 PF01433.20 PSC75184.1 - 1.3e-59 201.4 0.0 1.3e-54 185.0 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M1 domain ERAP1_C PF11838.8 PSC75184.1 - 1.1e-44 153.3 0.1 2.1e-44 152.4 0.1 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 PSC75184.1 - 2.8e-38 132.0 0.0 4.6e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain WD40 PF00400.32 PSC75184.1 - 8.8e-16 58.0 7.8 0.00046 20.9 0.0 7.4 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC75184.1 - 5.6e-05 23.4 0.3 9.3 6.6 0.0 4.9 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 PSC75184.1 - 0.14 12.7 4.1 6.8 7.3 0.1 4.2 4 0 0 4 4 4 0 PQQ-like domain CDC45 PF02724.14 PSC75184.1 - 0.47 8.7 6.6 0.67 8.2 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4366 PF14283.6 PSC75184.1 - 2 8.4 4.9 5.4 7.1 4.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) Peptidase_M1 PF01433.20 PSC75185.1 - 8.7e-62 208.5 0.0 8.8e-57 192.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase family M1 domain ERAP1_C PF11838.8 PSC75185.1 - 1.1e-44 153.3 0.1 2.1e-44 152.4 0.1 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 PSC75185.1 - 2.7e-38 132.0 0.0 4.6e-38 131.3 0.0 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain WD40 PF00400.32 PSC75185.1 - 8.6e-16 58.1 7.8 0.00045 21.0 0.0 7.4 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC75185.1 - 5.5e-05 23.4 0.3 9.3 6.6 0.0 4.9 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 PSC75185.1 - 0.14 12.7 4.1 6.8 7.3 0.1 4.2 4 0 0 4 4 4 0 PQQ-like domain CDC45 PF02724.14 PSC75185.1 - 0.47 8.7 6.6 0.67 8.2 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4366 PF14283.6 PSC75185.1 - 2 8.4 4.9 5.4 7.1 4.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF775 PF05603.12 PSC75186.1 - 0.051 13.1 10.1 0.12 11.9 10.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF775) Suf PF05843.14 PSC75186.1 - 0.31 11.0 5.9 0.29 11.1 5.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) UPF0524 PF15823.5 PSC75186.1 - 0.39 10.1 5.7 1.4 8.3 5.7 1.8 1 1 0 1 1 1 0 UPF0524 of C3orf70 DUF4199 PF13858.6 PSC75186.1 - 0.88 10.0 3.6 1.1 9.7 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF2059 PF09832.9 PSC75186.1 - 1.2 9.2 0.0 1.2 9.2 0.0 3.5 2 1 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2059) TFIIA PF03153.13 PSC75186.1 - 1.8 8.5 21.7 1.8 8.5 21.7 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GTSE1_N PF15259.6 PSC75186.1 - 2.4 8.3 6.9 3.6 7.7 6.9 1.2 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 Presenilin PF01080.17 PSC75186.1 - 2.9 6.6 5.8 3.2 6.4 5.8 1.1 1 0 0 1 1 1 0 Presenilin MCU PF04678.13 PSC75186.1 - 7.3 6.7 8.4 10 6.2 8.4 1.2 1 0 0 1 1 1 0 Mitochondrial calcium uniporter UPF0560 PF10577.9 PSC75186.1 - 7.7 4.9 10.6 7.9 4.8 10.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FKBP_C PF00254.28 PSC75187.1 - 3.2e-61 203.6 0.0 5.3e-32 110.0 0.0 3.3 3 0 0 3 3 3 3 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 PSC75187.1 - 2e-06 27.5 6.0 0.028 14.5 0.1 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 PSC75187.1 - 2.7e-05 23.8 5.3 0.22 11.4 0.0 4.1 3 1 0 3 3 3 2 Tetratricopeptide repeat FKBP_N_2 PF18023.1 PSC75187.1 - 3.1e-05 24.0 0.0 0.17 12.0 0.0 4.5 3 2 0 3 3 3 1 BDBT FKBP like N-terminal TPR_19 PF14559.6 PSC75187.1 - 0.00084 19.8 5.1 0.0078 16.7 2.1 2.9 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 PSC75187.1 - 0.0061 17.2 6.8 0.0061 17.2 6.8 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 PSC75187.1 - 0.07 13.2 3.4 2.1 8.6 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 PSC75187.1 - 0.13 12.7 0.8 1.3 9.6 0.1 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PSC75187.1 - 0.16 12.0 0.4 32 4.7 0.1 2.8 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 PSC75187.1 - 0.18 12.1 2.3 1.1 9.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 PSC75187.1 - 0.58 9.9 3.5 0.25 11.1 0.2 2.2 3 0 0 3 3 3 0 TPR repeat TPR_14 PF13428.6 PSC75187.1 - 3.5 8.7 16.0 0.17 12.8 0.9 4.1 3 1 1 4 4 4 0 Tetratricopeptide repeat Pyrid_oxidase_2 PF13883.6 PSC75188.1 - 3.8e-17 62.8 0.0 9.8e-17 61.4 0.0 1.7 1 1 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase DUF2470 PF10615.9 PSC75188.1 - 1.8e-14 54.1 0.1 3.7e-14 53.1 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Putative_PNPOx PF01243.20 PSC75188.1 - 8.6e-11 41.9 0.0 2.2e-10 40.6 0.0 1.7 2 0 0 2 2 2 1 Pyridoxamine 5'-phosphate oxidase Ribosomal_60s PF00428.19 PSC75188.1 - 0.069 13.7 0.5 0.069 13.7 0.5 3.3 3 1 0 3 3 3 0 60s Acidic ribosomal protein Pyridox_ox_2 PF12900.7 PSC75188.1 - 0.11 12.5 0.8 0.66 10.0 0.0 2.7 2 1 0 2 2 2 0 Pyridoxamine 5'-phosphate oxidase DUF5591 PF17884.1 PSC75188.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5591) Carboxyl_trans PF01039.22 PSC75189.1 - 1.2e-145 486.0 0.0 1.8e-145 485.4 0.0 1.3 1 0 0 1 1 1 1 Carboxyl transferase domain ACC_central PF08326.12 PSC75189.1 - 3.5e-88 296.7 0.0 5.2e-53 180.4 0.0 3.1 3 0 0 3 3 3 3 Acetyl-CoA carboxylase, central region CPSase_L_D2 PF02786.17 PSC75189.1 - 1.1e-45 155.7 0.0 6.1e-45 153.3 0.0 2.1 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 PSC75189.1 - 5.6e-27 94.5 0.0 1.3e-26 93.3 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 PSC75189.1 - 5.3e-23 81.2 0.0 5.6e-22 77.9 0.0 2.8 3 0 0 3 3 3 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 PSC75189.1 - 2.8e-11 43.1 0.0 6.5e-11 41.9 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp_3 PF02655.14 PSC75189.1 - 3.7e-06 27.1 0.0 9.1e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 ATP-grasp domain ATP-grasp PF02222.22 PSC75189.1 - 9.4e-06 25.3 0.0 2.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain LAL_C2 PF18603.1 PSC75189.1 - 0.016 15.4 0.2 0.12 12.6 0.0 2.7 2 0 0 2 2 2 0 L-amino acid ligase C-terminal domain 2 Dala_Dala_lig_C PF07478.13 PSC75189.1 - 0.095 12.2 0.0 0.34 10.4 0.0 1.9 2 1 0 2 2 2 0 D-ala D-ala ligase C-terminus Oxysterol_BP PF01237.18 PSC75190.1 - 6.8e-94 314.7 0.0 1e-93 314.2 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein Ephrin_rec_like PF07699.13 PSC75190.1 - 6.5e-40 134.7 153.0 8.5e-08 31.9 2.4 18.5 9 3 10 20 20 20 13 Putative ephrin-receptor like NCD3G PF07562.14 PSC75190.1 - 1.6e-12 47.2 90.9 0.0021 18.0 5.2 13.8 10 5 3 14 14 14 9 Nine Cysteines Domain of family 3 GPCR bZIP_1 PF00170.21 PSC75190.1 - 8.7e-09 35.4 5.1 1.7e-08 34.5 5.1 1.3 1 0 0 1 1 1 1 bZIP transcription factor bZIP_Maf PF03131.17 PSC75190.1 - 0.00078 19.9 6.1 0.0013 19.2 6.1 1.3 1 0 0 1 1 1 1 bZIP Maf transcription factor bZIP_2 PF07716.15 PSC75190.1 - 0.0057 16.7 6.0 0.011 15.8 6.0 1.4 1 0 0 1 1 1 1 Basic region leucine zipper Syja_N PF02383.18 PSC75191.1 - 8.6e-66 222.4 0.0 1.1e-65 222.0 0.0 1.1 1 0 0 1 1 1 1 SacI homology domain PsbX PF06596.11 PSC75192.1 - 8.4e-12 44.9 2.7 8.4e-12 44.9 2.7 2.6 3 0 0 3 3 3 1 Photosystem II reaction centre X protein (PsbX) MSP1_C PF07462.11 PSC75192.1 - 0.95 8.1 3.5 1 8.0 3.5 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus PseudoU_synth_2 PF00849.22 PSC75194.1 - 3e-16 59.9 0.0 1.5e-09 38.2 0.0 2.3 2 0 0 2 2 2 2 RNA pseudouridylate synthase PBP_N PF17093.5 PSC75194.1 - 2.1 8.6 10.1 1.5 9.0 8.1 1.7 2 0 0 2 2 2 0 Penicillin-binding protein N-terminus UCH PF00443.29 PSC75195.1 - 7e-44 150.2 0.0 7.9e-16 58.3 0.0 5.2 3 2 1 4 4 4 4 Ubiquitin carboxyl-terminal hydrolase Bestrophin PF01062.21 PSC75195.1 - 5.8e-31 108.0 20.5 7.7e-14 51.8 0.5 6.0 4 2 1 6 6 6 3 Bestrophin, RFP-TM, chloride channel UCH_1 PF13423.6 PSC75195.1 - 3.3e-10 40.0 0.5 0.018 14.6 0.0 5.8 5 2 0 6 6 6 2 Ubiquitin carboxyl-terminal hydrolase zf-FPG_IleRS PF06827.14 PSC75195.1 - 0.0012 18.6 0.5 2.7 7.9 0.1 2.8 2 0 0 2 2 2 2 Zinc finger found in FPG and IleRS UBA PF00627.31 PSC75195.1 - 0.0045 16.9 4.7 0.15 12.0 0.4 3.0 2 0 0 2 2 2 1 UBA/TS-N domain MCRA PF06100.11 PSC75195.1 - 0.082 11.7 1.2 5.5 5.7 0.1 2.9 3 0 0 3 3 3 0 MCRA family PriA_CRR PF18319.1 PSC75195.1 - 0.22 11.6 2.2 22 5.1 0.2 2.8 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain DAGK_prokar PF01219.19 PSC75195.1 - 0.53 10.1 8.3 2.2 8.2 0.4 3.6 3 0 0 3 3 3 0 Prokaryotic diacylglycerol kinase Ost4 PF10215.9 PSC75195.1 - 0.57 10.0 4.6 69 3.4 0.1 3.3 3 0 0 3 3 3 0 Oligosaccaryltransferase Zn-ribbon_8 PF09723.10 PSC75195.1 - 1.3 9.2 8.4 3.6 7.8 1.2 3.4 3 0 0 3 3 3 0 Zinc ribbon domain DZR PF12773.7 PSC75195.1 - 2.2 8.4 4.4 5.6 7.1 0.5 2.9 3 0 0 3 3 3 0 Double zinc ribbon Ogr_Delta PF04606.12 PSC75195.1 - 6.7 6.8 5.4 52 3.9 0.5 2.9 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger AAA_11 PF13086.6 PSC75196.1 - 6.4e-58 196.6 0.0 1.2e-57 195.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_12 PF13087.6 PSC75196.1 - 8.1e-57 192.1 0.0 1.3e-56 191.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thioredoxin PF00085.20 PSC75196.1 - 4e-28 97.4 0.0 2.3e-24 85.3 0.0 3.6 3 0 0 3 3 3 1 Thioredoxin Guanylate_cyc PF00211.20 PSC75196.1 - 4.5e-16 59.0 0.0 1.4e-10 41.1 0.0 2.5 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain LRRNT_2 PF08263.12 PSC75196.1 - 8.1e-11 42.1 0.4 2e-10 40.8 0.4 1.7 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_4 PF12799.7 PSC75196.1 - 8.4e-07 29.2 0.8 0.0092 16.4 0.0 2.6 2 0 0 2 2 2 2 Leucine Rich repeats (2 copies) AAA_30 PF13604.6 PSC75196.1 - 1.3e-06 28.2 4.2 0.012 15.4 0.8 3.4 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.6 PSC75196.1 - 1.4e-06 28.7 0.4 2.7e-05 24.5 0.4 2.7 1 1 0 1 1 1 1 AAA domain LRR_8 PF13855.6 PSC75196.1 - 1.7e-05 24.5 4.0 2.8e-05 23.8 3.2 1.8 2 0 0 2 2 1 1 Leucine rich repeat Thioredoxin_2 PF13098.6 PSC75196.1 - 8.4e-05 23.0 0.1 0.07 13.6 0.0 2.8 2 0 0 2 2 2 1 Thioredoxin-like domain Viral_helicase1 PF01443.18 PSC75196.1 - 0.00011 22.1 0.0 0.12 12.1 0.0 3.2 3 0 0 3 3 3 1 Viral (Superfamily 1) RNA helicase UvrD_C_2 PF13538.6 PSC75196.1 - 0.00038 20.2 0.0 0.0012 18.6 0.0 1.9 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Thioredoxin_8 PF13905.6 PSC75196.1 - 0.037 14.3 0.0 0.12 12.7 0.0 1.8 2 0 0 2 2 1 0 Thioredoxin-like AAA PF00004.29 PSC75196.1 - 0.051 14.0 0.2 0.45 10.9 0.0 2.6 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PSC75196.1 - 0.06 13.7 0.5 0.66 10.3 0.0 3.1 3 0 0 3 3 2 0 AAA ATPase domain UvrD-helicase PF00580.21 PSC75196.1 - 0.065 12.7 0.0 1.3 8.4 0.0 2.7 2 1 0 2 2 2 0 UvrD/REP helicase N-terminal domain Thioredoxin_7 PF13899.6 PSC75196.1 - 0.16 12.2 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 Thioredoxin-like YqaJ PF09588.10 PSC75197.1 - 1.5e-20 73.9 0.0 2.7e-20 73.0 0.0 1.4 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain TFIIA PF03153.13 PSC75197.1 - 0.0048 17.0 27.0 0.0068 16.4 27.0 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit RIFIN PF02009.16 PSC75197.1 - 0.64 9.9 4.8 1.2 9.0 4.8 1.3 1 0 0 1 1 1 0 Rifin Suf PF05843.14 PSC75197.1 - 4.9 7.1 15.2 8.3 6.3 15.2 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) PAT1 PF09770.9 PSC75197.1 - 7.4 4.7 21.6 9.7 4.3 21.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 BAF1_ABF1 PF04684.13 PSC75197.1 - 9.8 5.1 9.8 14 4.6 9.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Rad51 PF08423.11 PSC75198.1 - 3.3e-43 147.8 0.0 5.8e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 Rad51 Na_H_Exchanger PF00999.21 PSC75198.1 - 4.5e-27 94.8 32.7 7.3e-27 94.1 32.7 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family AAA_25 PF13481.6 PSC75198.1 - 1e-06 28.5 1.2 1e-06 28.5 1.2 2.6 3 0 0 3 3 3 1 AAA domain ATPase PF06745.13 PSC75198.1 - 3.7e-05 23.2 0.4 0.00012 21.5 0.4 1.7 1 1 0 1 1 1 1 KaiC DnaB_C PF03796.15 PSC75198.1 - 9.7e-05 21.8 0.0 0.00021 20.7 0.0 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain RecA PF00154.21 PSC75198.1 - 0.032 13.7 0.5 2.2 7.7 0.1 2.2 2 0 0 2 2 2 0 recA bacterial DNA recombination protein CCDC53 PF10152.9 PSC75198.1 - 8.2 6.8 9.4 25 5.3 6.0 2.7 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex PPR_2 PF13041.6 PSC75199.1 - 1.8e-81 268.1 6.7 6.4e-15 55.1 0.0 8.7 1 1 7 8 8 8 8 PPR repeat family PPR PF01535.20 PSC75199.1 - 2.6e-68 221.6 3.1 2.2e-09 36.9 0.0 10.0 10 0 0 10 10 10 8 PPR repeat PPR_3 PF13812.6 PSC75199.1 - 3.2e-66 219.3 0.0 6.2e-14 51.8 0.0 5.9 3 2 3 6 6 6 6 Pentatricopeptide repeat domain PPR_1 PF12854.7 PSC75199.1 - 8.4e-55 182.2 0.0 5.7e-10 38.7 0.0 10.3 10 0 0 10 10 10 7 PPR repeat PPR_long PF17177.4 PSC75199.1 - 1.3e-32 112.9 0.1 9.1e-18 64.4 0.0 2.3 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP TPR_19 PF14559.6 PSC75199.1 - 1.3e-06 28.8 0.0 0.56 10.8 0.0 5.5 4 1 1 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 PSC75199.1 - 9.8e-06 26.0 17.0 3.8 8.6 0.1 10.0 8 3 3 11 11 9 1 Tetratricopeptide repeat MRP-S27 PF10037.9 PSC75199.1 - 1.9e-05 23.8 0.0 0.0066 15.4 0.0 3.4 1 1 3 4 4 4 2 Mitochondrial 28S ribosomal protein S27 TPR_7 PF13176.6 PSC75199.1 - 3.7e-05 23.5 4.8 33 4.8 0.0 7.3 8 0 0 8 8 8 0 Tetratricopeptide repeat Cyclin_C PF02984.19 PSC75199.1 - 0.00014 21.9 0.0 0.00014 21.9 0.0 2.6 3 0 0 3 3 2 1 Cyclin, C-terminal domain Clathrin PF00637.20 PSC75199.1 - 0.00018 21.4 0.0 0.48 10.3 0.0 3.8 1 1 0 3 3 3 1 Region in Clathrin and VPS PYRIN PF02758.16 PSC75199.1 - 0.0003 20.8 0.7 20 5.4 0.0 4.5 5 0 0 5 5 4 0 PAAD/DAPIN/Pyrin domain BTAD PF03704.17 PSC75199.1 - 0.0026 18.2 5.7 3.1 8.2 0.0 4.8 3 1 1 4 4 4 1 Bacterial transcriptional activator domain Cyclin_N PF00134.23 PSC75199.1 - 0.0073 16.0 0.0 0.014 15.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Smr PF01713.21 PSC75199.1 - 0.042 14.2 0.0 0.14 12.5 0.0 1.9 1 0 0 1 1 1 0 Smr domain TPR_11 PF13414.6 PSC75199.1 - 0.069 12.9 0.1 14 5.5 0.0 3.6 3 0 0 3 3 3 0 TPR repeat TPR_1 PF00515.28 PSC75199.1 - 0.075 12.9 3.3 63 3.6 0.0 5.0 8 0 0 8 8 6 0 Tetratricopeptide repeat ChAPs PF09295.10 PSC75199.1 - 0.13 11.3 0.0 0.25 10.3 0.0 1.4 1 0 0 1 1 1 0 ChAPs (Chs5p-Arf1p-binding proteins) Tcp10_C PF07202.13 PSC75200.1 - 1.2e-20 74.2 0.0 1.9e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 T-complex protein 10 C-terminus Exonuc_VII_L PF02601.15 PSC75200.1 - 0.95 9.0 13.8 2.1 7.9 13.8 1.6 1 0 0 1 1 1 0 Exonuclease VII, large subunit SlyX PF04102.12 PSC75200.1 - 3.1 8.5 20.2 3.3 8.4 0.3 3.9 2 1 1 3 3 3 0 SlyX Pectate_lyase_3 PF12708.7 PSC75203.1 - 7.2e-17 61.9 0.1 1.2e-14 54.7 0.0 2.4 2 0 0 2 2 2 2 Pectate lyase superfamily protein End_N_terminal PF12218.8 PSC75203.1 - 0.0019 17.9 0.3 0.0047 16.6 0.3 1.7 1 0 0 1 1 1 1 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.6 PSC75203.1 - 0.022 14.6 0.1 0.043 13.7 0.1 1.5 1 0 0 1 1 1 0 Right handed beta helix region Ribosomal_L13 PF00572.18 PSC75204.1 - 6.5e-43 145.9 0.0 1.5e-42 144.7 0.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L13 DEAD PF00270.29 PSC75205.1 - 4.5e-17 62.4 0.0 1.2e-16 60.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 PSC75205.1 - 9.2e-16 58.3 0.0 1.7e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PSC75205.1 - 1.1e-11 45.1 0.0 2.1e-11 44.2 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 PSC75205.1 - 0.019 15.2 0.0 0.068 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 PSC75205.1 - 0.029 13.8 0.1 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Proteasom_PSMB PF10508.9 PSC75205.1 - 0.067 11.7 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit IstB_IS21 PF01695.17 PSC75205.1 - 0.11 12.2 0.0 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein DEAD PF00270.29 PSC75206.1 - 4.5e-17 62.4 0.0 1.2e-16 60.9 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 PSC75206.1 - 9.3e-16 58.3 0.0 1.7e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 PSC75206.1 - 1.1e-11 45.1 0.0 2.1e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 PSC75206.1 - 0.02 15.2 0.0 0.068 13.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 PSC75206.1 - 0.029 13.8 0.1 0.12 11.8 0.0 1.9 2 0 0 2 2 2 0 PhoH-like protein Proteasom_PSMB PF10508.9 PSC75206.1 - 0.067 11.7 0.0 0.12 10.9 0.0 1.3 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit IstB_IS21 PF01695.17 PSC75206.1 - 0.12 12.1 0.0 2.4 7.9 0.0 2.2 2 0 0 2 2 2 0 IstB-like ATP binding protein TENA_THI-4 PF03070.16 PSC75207.1 - 7.8e-28 97.7 0.2 9.3e-28 97.5 0.2 1.0 1 0 0 1 1 1 1 TENA/THI-4/PQQC family Phos_pyr_kin PF08543.12 PSC75208.1 - 2.4e-86 289.1 1.9 4.1e-86 288.4 0.7 2.0 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase TMP-TENI PF02581.17 PSC75208.1 - 2.5e-59 199.7 6.4 5.2e-59 198.6 6.4 1.6 1 0 0 1 1 1 1 Thiamine monophosphate synthase TENA_THI-4 PF03070.16 PSC75208.1 - 2.9e-28 99.1 0.3 4.7e-28 98.4 0.3 1.3 1 0 0 1 1 1 1 TENA/THI-4/PQQC family HAD PF12710.7 PSC75208.1 - 1.6e-07 31.9 2.6 6e-05 23.5 1.3 4.5 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase NMO PF03060.15 PSC75208.1 - 4.8e-05 22.9 8.8 0.00012 21.6 8.8 1.6 1 0 0 1 1 1 1 Nitronate monooxygenase Phos_pyr_kin PF08543.12 PSC75209.1 - 2.9e-86 288.8 0.7 2.9e-86 288.8 0.7 2.2 3 0 0 3 3 3 1 Phosphomethylpyrimidine kinase TMP-TENI PF02581.17 PSC75209.1 - 1.9e-59 200.0 6.4 3.9e-59 199.0 6.4 1.6 1 0 0 1 1 1 1 Thiamine monophosphate synthase HAD PF12710.7 PSC75209.1 - 1.1e-07 32.4 2.7 4.2e-05 24.0 1.2 4.3 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase NMO PF03060.15 PSC75209.1 - 3.6e-05 23.3 8.8 9e-05 22.0 8.8 1.6 1 0 0 1 1 1 1 Nitronate monooxygenase Phos_pyr_kin PF08543.12 PSC75210.1 - 5.5e-86 287.9 0.6 5.5e-86 287.9 0.6 2.2 3 0 0 3 3 3 1 Phosphomethylpyrimidine kinase TMP-TENI PF02581.17 PSC75210.1 - 1.9e-59 200.0 6.4 3.9e-59 199.0 6.4 1.6 1 0 0 1 1 1 1 Thiamine monophosphate synthase HAD PF12710.7 PSC75210.1 - 1.1e-07 32.4 2.7 4.2e-05 24.0 1.2 4.3 3 1 0 3 3 3 1 haloacid dehalogenase-like hydrolase NMO PF03060.15 PSC75210.1 - 3.6e-05 23.3 8.8 9.1e-05 22.0 8.8 1.6 1 0 0 1 1 1 1 Nitronate monooxygenase Peptidase_C1 PF00112.23 PSC75211.1 - 1.2e-41 143.2 1.0 1.7e-41 142.8 1.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 PSC75211.1 - 0.0053 15.6 0.4 0.009 14.8 0.4 1.3 1 0 0 1 1 1 1 Peptidase C1-like family DUF998 PF06197.13 PSC75211.1 - 7.3 6.1 12.0 8.1 6.0 6.8 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF998) Peptidase_C1 PF00112.23 PSC75212.1 - 1.1e-41 143.3 1.0 1.6e-41 142.8 1.0 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 PSC75212.1 - 0.0052 15.6 0.4 0.0088 14.9 0.4 1.3 1 0 0 1 1 1 1 Peptidase C1-like family DUF998 PF06197.13 PSC75212.1 - 5.6 6.5 11.5 0.3 10.6 1.6 3.2 3 1 0 4 4 4 0 Protein of unknown function (DUF998) DUF2428 PF10350.9 PSC75213.1 - 2.1e-62 210.9 0.0 3.7e-62 210.1 0.0 1.4 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 PSC75213.1 - 5.2 7.6 23.9 46 4.7 0.0 8.2 7 0 0 7 7 7 0 HEAT repeat SecE PF00584.20 PSC75214.1 - 0.012 15.5 0.0 0.02 14.8 0.0 1.3 1 0 0 1 1 1 0 SecE/Sec61-gamma subunits of protein translocation complex IBR PF01485.21 PSC75215.1 - 6e-17 61.6 44.2 6.5e-11 42.3 12.6 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain UBA_4 PF14555.6 PSC75215.1 - 0.00026 20.8 0.0 0.00067 19.4 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain zf-RING_UBOX PF13445.6 PSC75215.1 - 0.0011 18.9 4.5 0.0011 18.9 4.5 3.4 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PSC75215.1 - 0.0031 17.3 5.6 0.0031 17.3 5.6 4.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC75215.1 - 0.0037 17.1 5.8 0.0037 17.1 5.8 4.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC75215.1 - 0.016 15.1 7.9 0.016 15.1 7.9 3.4 3 0 0 3 3 3 0 zinc-RING finger domain IBR PF01485.21 PSC75216.1 - 5.1e-17 61.8 44.2 6.3e-11 42.3 12.6 4.3 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain UBA_4 PF14555.6 PSC75216.1 - 0.00023 20.9 0.0 0.00061 19.6 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain zf-RING_UBOX PF13445.6 PSC75216.1 - 0.0011 19.0 4.5 0.0011 19.0 4.5 3.4 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 PSC75216.1 - 0.003 17.4 5.6 0.003 17.4 5.6 4.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC75216.1 - 0.0036 17.2 5.8 0.0036 17.2 5.8 4.2 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC75216.1 - 0.016 15.2 7.9 0.016 15.2 7.9 3.4 3 0 0 3 3 3 0 zinc-RING finger domain DcpS_C PF11969.8 PSC75217.1 - 1.3e-21 77.2 0.0 2.1e-21 76.5 0.0 1.3 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding AAA_33 PF13671.6 PSC75217.1 - 9.1e-17 61.6 0.3 2.8e-16 60.0 0.3 1.9 1 0 0 1 1 1 1 AAA domain HIT PF01230.23 PSC75217.1 - 2.5e-09 37.8 0.0 5.4e-09 36.7 0.0 1.6 1 0 0 1 1 1 1 HIT domain zf-C2HE PF16278.5 PSC75217.1 - 2e-07 31.3 0.0 4.1e-07 30.4 0.0 1.4 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger Zeta_toxin PF06414.12 PSC75217.1 - 0.00032 20.0 0.7 0.13 11.5 0.1 2.9 3 0 0 3 3 3 2 Zeta toxin AAA_18 PF13238.6 PSC75217.1 - 0.0007 20.2 0.0 0.0014 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 PSC75217.1 - 0.0077 15.9 0.0 0.41 10.3 0.0 2.6 2 1 0 2 2 2 1 Thymidylate kinase ABC_tran PF00005.27 PSC75217.1 - 0.023 15.2 0.1 0.05 14.1 0.1 1.5 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 PSC75217.1 - 0.026 14.9 0.1 0.07 13.5 0.1 1.8 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 PSC75217.1 - 0.027 14.8 0.0 0.063 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 PSC75217.1 - 0.044 13.4 0.0 0.076 12.6 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Septin PF00735.18 PSC75217.1 - 0.12 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Septin AAA_17 PF13207.6 PSC75217.1 - 0.13 12.7 2.0 1.1 9.7 0.0 2.6 3 0 0 3 3 2 0 AAA domain ATP_bind_1 PF03029.17 PSC75217.1 - 0.18 11.6 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 PSC75217.1 - 0.21 11.7 0.0 0.39 10.8 0.0 1.4 1 0 0 1 1 1 0 50S ribosome-binding GTPase KTI12 PF08433.10 PSC75217.1 - 0.29 10.6 0.0 1.3 8.4 0.0 1.8 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Zip PF02535.22 PSC75218.1 - 9e-38 130.3 5.3 1.4e-37 129.7 5.3 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter DUF4277 PF14104.6 PSC75218.1 - 0.041 14.3 0.1 0.086 13.2 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4277) Wzy_C PF04932.15 PSC75218.1 - 1 9.0 5.8 0.21 11.2 0.2 2.4 2 0 0 2 2 2 0 O-Antigen ligase LHC PF00556.20 PSC75218.1 - 5 7.4 5.6 31 4.9 0.5 3.3 2 0 0 2 2 2 0 Antenna complex alpha/beta subunit Brix PF04427.18 PSC75219.1 - 1.8e-33 116.2 0.0 2.4e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Brix domain V-SNARE_C PF12352.8 PSC75220.1 - 6.6e-17 61.6 10.1 6.6e-17 61.6 10.1 1.8 1 1 1 2 2 2 2 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 PSC75220.1 - 9.3e-05 22.3 1.7 0.00026 20.9 1.4 1.7 1 1 1 2 2 2 1 Sec20 V-SNARE PF05008.15 PSC75220.1 - 0.017 15.5 3.9 0.093 13.1 0.2 2.6 2 1 1 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF745 PF05335.13 PSC75220.1 - 0.23 11.2 1.9 1.9 8.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF745) SNARE PF05739.19 PSC75220.1 - 0.26 11.3 1.9 1.2 9.2 0.4 2.2 2 0 0 2 2 2 0 SNARE domain DPBB_1 PF03330.18 PSC75221.1 - 9.7e-05 22.6 0.0 0.00036 20.8 0.0 2.0 2 0 0 2 2 2 1 Lytic transglycolase Ephrin_rec_like PF07699.13 PSC75222.1 - 9.9e-42 140.5 181.7 1.1e-09 37.9 7.4 20.3 9 5 13 22 22 22 17 Putative ephrin-receptor like NCD3G PF07562.14 PSC75222.1 - 4.3e-17 61.8 120.6 0.00063 19.7 6.4 15.2 12 3 2 15 15 15 11 Nine Cysteines Domain of family 3 GPCR TNFR_c6 PF00020.18 PSC75222.1 - 1 9.8 117.6 0.4 11.1 0.5 19.2 9 6 11 21 21 21 0 TNFR/NGFR cysteine-rich region DUF4684 PF15736.5 PSC75222.1 - 3.6 6.2 6.6 7.8 5.1 6.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4684) Glyco_transf_92 PF01697.27 PSC75223.1 - 4.2e-15 56.1 0.0 5.9e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PSC75223.1 - 2.1e-10 40.9 0.1 4.5e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_92 PF01697.27 PSC75224.1 - 4.2e-15 56.1 0.0 5.9e-15 55.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PSC75224.1 - 2.1e-10 40.9 0.1 4.5e-10 39.9 0.1 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 PMM PF03332.13 PSC75225.1 - 6.7e-106 353.0 0.2 1.1e-105 352.3 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Ephrin_rec_like PF07699.13 PSC75225.1 - 2e-35 120.3 175.0 3.8e-07 29.8 5.1 20.8 7 4 13 21 21 21 16 Putative ephrin-receptor like NCD3G PF07562.14 PSC75225.1 - 6.4e-11 42.0 120.6 0.035 14.1 6.1 15.6 8 4 4 16 16 16 10 Nine Cysteines Domain of family 3 GPCR Hydrolase_3 PF08282.12 PSC75225.1 - 0.00042 20.2 0.0 0.00076 19.3 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase RelA_SpoT PF04607.17 PSC75226.1 - 5.6e-19 68.5 0.0 9.9e-19 67.8 0.0 1.4 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins TPR_17 PF13431.6 PSC75226.1 - 7.6e-19 66.7 2.7 0.0099 16.2 0.0 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 PSC75226.1 - 5.3e-17 60.5 15.1 0.0057 16.7 0.2 7.8 7 0 0 7 7 7 5 Tetratricopeptide repeat FHA PF00498.26 PSC75226.1 - 4.2e-13 49.4 0.0 3.9e-11 43.1 0.0 2.3 2 0 0 2 2 2 1 FHA domain TPR_8 PF13181.6 PSC75226.1 - 5.1e-11 41.9 0.4 0.1 12.9 0.0 6.5 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 PSC75226.1 - 3.3e-08 33.0 0.2 1.4 8.9 0.1 6.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 PSC75226.1 - 5e-08 33.3 38.6 1.5e-05 25.4 1.5 7.0 4 3 1 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 PSC75226.1 - 1.8e-07 31.7 8.3 1.8e-07 31.7 8.3 9.6 9 1 1 10 10 6 3 Tetratricopeptide repeat TPR_14 PF13428.6 PSC75226.1 - 1.5e-06 28.5 16.8 5.4e-06 26.8 3.5 11.9 7 2 7 14 14 10 7 Tetratricopeptide repeat EF-hand_1 PF00036.32 PSC75226.1 - 3.3e-06 26.3 0.0 2.3e-05 23.6 0.0 2.1 2 0 0 2 2 2 1 EF hand TPR_12 PF13424.6 PSC75226.1 - 5.5e-06 26.6 4.0 5.5e-06 26.6 4.0 6.7 3 1 5 8 8 8 5 Tetratricopeptide repeat EF-hand_6 PF13405.6 PSC75226.1 - 2.3e-05 24.0 0.0 6.6e-05 22.5 0.0 1.8 1 0 0 1 1 1 1 EF-hand domain EF-hand_8 PF13833.6 PSC75226.1 - 4e-05 23.4 0.0 0.00025 20.8 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 PSC75226.1 - 4.1e-05 22.9 0.0 8.4e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 PSC75226.1 - 9.1e-05 22.8 0.0 0.00021 21.7 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain pair TPR_6 PF13174.6 PSC75226.1 - 0.00013 22.4 7.8 1.7 9.4 0.0 6.2 5 0 0 5 5 5 2 Tetratricopeptide repeat Yop-YscD_cpl PF16697.5 PSC75226.1 - 0.00029 21.1 0.0 0.00099 19.4 0.0 1.9 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain TPR_11 PF13414.6 PSC75226.1 - 0.015 14.9 3.9 14 5.5 0.0 5.0 2 1 3 5 5 5 0 TPR repeat Sod_Fe_C PF02777.18 PSC75227.1 - 1.4e-34 118.3 0.0 2.5e-34 117.5 0.0 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 PSC75227.1 - 4.8e-13 49.4 0.0 1e-12 48.4 0.0 1.6 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain rve PF00665.26 PSC75228.1 - 6.3e-19 68.3 0.0 1.3e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC75228.1 - 0.0058 16.4 0.0 0.015 15.0 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain COX15-CtaA PF02628.15 PSC75229.1 - 2e-101 339.3 14.5 2.8e-101 338.8 14.5 1.2 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein NAD_kinase PF01513.21 PSC75230.1 - 3.9e-57 193.7 0.1 1.3e-56 192.0 0.0 1.7 2 0 0 2 2 2 1 ATP-NAD kinase ARGLU PF15346.6 PSC75230.1 - 0.0057 16.5 5.8 0.0057 16.5 5.8 1.6 2 0 0 2 2 2 1 Arginine and glutamate-rich 1 DAGK_cat PF00781.24 PSC75230.1 - 0.046 13.3 0.8 0.15 11.7 0.5 2.0 2 0 0 2 2 2 0 Diacylglycerol kinase catalytic domain UCR_hinge PF02320.16 PSC75231.1 - 9.2e-23 80.2 7.8 1e-22 80.1 7.8 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.12 PSC75231.1 - 0.2 11.9 8.2 0.73 10.1 1.9 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) CBM_20 PF00686.19 PSC75232.1 - 2.9e-14 52.7 0.0 5.8e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Starch binding domain CBM_20 PF00686.19 PSC75233.1 - 3.1e-14 52.7 0.0 6e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Starch binding domain SelK_SelG PF10961.8 PSC75233.1 - 3.1 8.5 5.5 14 6.4 5.5 2.1 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Str_synth PF03088.16 PSC75234.1 - 1.6e-18 66.6 0.0 9.7e-18 64.1 0.0 2.1 1 1 0 1 1 1 1 Strictosidine synthase SGL PF08450.12 PSC75234.1 - 3.9e-10 39.7 0.0 1.6e-09 37.7 0.0 2.0 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 PSC75234.1 - 0.29 11.5 2.9 51 4.6 0.3 4.4 5 0 0 5 5 5 0 Two component regulator propeller DUF3185 PF11381.8 PSC75235.1 - 0.06 13.4 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3185) PAF-AH_p_II PF03403.13 PSC75236.1 - 3.2e-40 137.8 0.0 3.2e-40 137.8 0.0 4.3 3 2 1 4 4 4 1 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase2 PF12740.7 PSC75236.1 - 7.5e-05 21.8 0.0 0.00024 20.1 0.0 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme RNA_pol_Rpc4 PF05132.14 PSC75236.1 - 0.0037 17.7 2.9 0.0037 17.7 2.9 7.5 4 3 2 6 6 6 1 RNA polymerase III RPC4 DDHD PF02862.17 PSC75236.1 - 0.0051 17.0 2.3 0.0051 17.0 2.3 4.6 3 1 0 3 3 3 1 DDHD domain BphX PF06139.12 PSC75236.1 - 0.054 13.4 0.0 0.1 12.6 0.0 1.3 1 0 0 1 1 1 0 BphX-like Chlorophyllase PF07224.11 PSC75236.1 - 1.4 7.9 3.9 5.5 5.9 0.1 2.8 3 0 0 3 3 3 0 Chlorophyllase Thioredoxin PF00085.20 PSC75237.1 - 6.1e-59 196.4 4.0 1.1e-27 96.0 0.0 4.4 3 1 1 4 4 4 3 Thioredoxin Thioredoxin_6 PF13848.6 PSC75237.1 - 2.7e-18 66.5 0.1 7.6e-14 52.0 0.0 3.3 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 PSC75237.1 - 4e-14 52.6 0.0 0.00035 20.7 0.0 4.1 4 0 0 4 4 4 3 Thioredoxin-like Thioredoxin_2 PF13098.6 PSC75237.1 - 4.4e-11 43.2 2.7 0.00096 19.6 0.0 4.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.6 PSC75237.1 - 1e-06 29.0 0.0 1.9 8.9 0.0 5.3 4 2 1 5 5 5 1 Thioredoxin-like OST3_OST6 PF04756.13 PSC75237.1 - 8.1e-05 22.1 0.0 0.28 10.5 0.0 2.3 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family Glutaredoxin PF00462.24 PSC75237.1 - 0.0018 18.4 2.8 1 9.6 0.0 4.1 3 1 0 3 3 3 1 Glutaredoxin Calsequestrin PF01216.17 PSC75237.1 - 0.0046 16.1 1.2 0.013 14.6 1.2 1.8 1 1 0 1 1 1 1 Calsequestrin TraF PF13728.6 PSC75237.1 - 0.04 13.7 0.0 0.96 9.2 0.0 2.5 2 0 0 2 2 2 0 F plasmid transfer operon protein DUF2514 PF10721.9 PSC75237.1 - 0.084 12.9 0.4 0.2 11.7 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) HyaE PF07449.11 PSC75237.1 - 0.085 12.8 0.0 15 5.6 0.0 3.5 3 1 0 4 4 4 0 Hydrogenase-1 expression protein HyaE RIIa PF02197.17 PSC75237.1 - 0.14 11.9 0.1 0.3 10.8 0.1 1.6 1 0 0 1 1 1 0 Regulatory subunit of type II PKA R-subunit PCI PF01399.27 PSC75238.1 - 3.9e-16 59.5 0.0 1.7e-15 57.4 0.0 2.0 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 PSC75238.1 - 4.6e-13 49.0 0.1 8.1e-13 48.2 0.1 1.4 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain AP2 PF00847.20 PSC75239.1 - 5e-05 23.5 0.1 9.5e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 AP2 domain SLX9 PF15341.6 PSC75239.1 - 0.037 14.4 5.5 0.13 12.6 1.5 2.3 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 EPL1 PF10513.9 PSC75239.1 - 0.36 11.2 3.1 0.18 12.2 0.5 1.7 2 0 0 2 2 2 0 Enhancer of polycomb-like Spt20 PF12090.8 PSC75239.1 - 0.42 10.2 19.5 0.033 13.8 10.8 2.1 2 0 0 2 2 2 0 Spt20 family GREB1 PF15782.5 PSC75239.1 - 0.65 7.1 4.1 0.8 6.7 4.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Presenilin PF01080.17 PSC75239.1 - 1 8.1 4.3 1.7 7.3 4.3 1.3 1 0 0 1 1 1 0 Presenilin ANAPC_CDC26 PF10471.9 PSC75239.1 - 1 10.2 21.0 0.097 13.5 11.8 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 Hydin_ADK PF17213.3 PSC75239.1 - 1.2 9.3 10.5 0.32 11.2 4.9 2.4 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain SLX9 PF15341.6 PSC75240.1 - 0.014 15.8 4.9 0.088 13.2 1.4 2.3 2 0 0 2 2 2 0 Ribosome biogenesis protein SLX9 EPL1 PF10513.9 PSC75240.1 - 0.22 11.9 3.0 0.12 12.7 0.4 1.8 2 0 0 2 2 2 0 Enhancer of polycomb-like Spt20 PF12090.8 PSC75240.1 - 0.22 11.1 19.4 0.021 14.5 10.5 2.1 2 0 0 2 2 2 0 Spt20 family GREB1 PF15782.5 PSC75240.1 - 0.46 7.5 4.1 0.56 7.3 4.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Hydin_ADK PF17213.3 PSC75240.1 - 1.1 9.5 10.5 0.22 11.8 4.8 2.1 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain Neur_chan_memb PF02932.16 PSC75240.1 - 5.6 7.0 5.2 3.7 7.6 1.6 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Suf PF05843.14 PSC75240.1 - 8.3 6.3 9.2 1.6 8.6 3.7 2.0 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) AIRS_C PF02769.22 PSC75241.1 - 3.8e-28 98.6 0.0 5.8e-28 98.0 0.0 1.3 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 PSC75241.1 - 1.3e-14 54.7 0.3 2.4e-14 53.7 0.3 1.5 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain PDDEXK_6 PF04720.12 PSC75242.1 - 6e-20 72.1 0.0 7.8e-20 71.8 0.0 1.1 1 0 0 1 1 1 1 PDDEXK-like family of unknown function S1 PF00575.23 PSC75243.1 - 2.1e-42 143.3 7.7 9.7e-22 77.1 0.8 3.2 3 0 0 3 3 3 3 S1 RNA binding domain PCB_OB PF17092.5 PSC75243.1 - 0.00023 21.9 0.4 1.6 9.5 0.0 3.6 2 2 1 3 3 3 2 Penicillin-binding protein OB-like domain S1_2 PF13509.6 PSC75243.1 - 0.0015 18.6 0.0 3.3 7.9 0.0 3.1 2 1 0 2 2 2 2 S1 domain DUF2110 PF09883.9 PSC75243.1 - 0.0077 15.8 0.0 0.28 10.8 0.0 2.2 2 0 0 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2110) IF3_C PF00707.22 PSC75243.1 - 0.11 12.5 0.0 0.45 10.5 0.0 2.0 2 0 0 2 2 2 0 Translation initiation factor IF-3, C-terminal domain EXOSC1 PF10447.9 PSC75243.1 - 0.61 10.7 3.2 32 5.2 0.1 3.3 2 2 0 2 2 2 0 Exosome component EXOSC1/CSL4 Aminotran_3 PF00202.21 PSC75244.1 - 5.2e-116 387.6 0.0 8.8e-116 386.9 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-III CBF PF03914.17 PSC75244.1 - 2e-50 171.1 1.1 8.3e-50 169.1 1.1 2.2 1 1 0 1 1 1 1 CBF/Mak21 family Ank_2 PF12796.7 PSC75245.1 - 5.5e-25 87.8 2.5 2.7e-12 47.1 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC75245.1 - 1.3e-23 83.1 0.7 1.7e-12 47.6 0.3 3.3 3 0 0 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC75245.1 - 2.6e-21 75.4 5.9 3.9e-07 30.2 0.2 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 PSC75245.1 - 1.3e-18 66.5 3.2 1.8e-05 25.0 0.4 4.4 3 1 1 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 PSC75245.1 - 3.2e-18 63.9 0.3 0.0054 17.1 0.1 4.4 4 0 0 4 4 4 4 Ankyrin repeat SRP-alpha_N PF04086.13 PSC75245.1 - 6.5 6.6 11.0 9.4 6.1 11.0 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal TPT PF03151.16 PSC75246.1 - 2.4e-51 174.8 20.9 2.8e-51 174.6 20.9 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PSC75246.1 - 7.8e-13 48.8 28.2 6.8e-08 32.8 10.2 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 PSC75246.1 - 8.3e-12 44.9 20.0 1.1e-11 44.5 20.0 1.1 1 0 0 1 1 1 1 UAA transporter family DHHC PF01529.20 PSC75247.1 - 5.4e-33 113.9 2.5 5.4e-33 113.9 2.5 2.0 2 0 0 2 2 2 1 DHHC palmitoyltransferase Adipogenin PF15202.6 PSC75247.1 - 0.094 12.8 0.1 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 Adipogenin DUF3172 PF11371.8 PSC75249.1 - 7.6e-55 184.4 0.3 8.7e-55 184.2 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3172) RIO1 PF01163.22 PSC75250.1 - 1.3e-69 233.6 0.0 1.3e-69 233.6 0.0 1.8 2 0 0 2 2 2 1 RIO1 family APH PF01636.23 PSC75250.1 - 0.0015 18.5 0.0 0.0015 18.5 0.0 4.3 4 1 1 5 5 5 2 Phosphotransferase enzyme family TFIIA PF03153.13 PSC75250.1 - 0.0037 17.3 23.3 0.0037 17.3 23.3 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Pkinase_fungal PF17667.1 PSC75250.1 - 0.0057 15.5 0.0 0.0057 15.5 0.0 2.1 2 1 0 2 2 2 1 Fungal protein kinase Pkinase PF00069.25 PSC75250.1 - 0.044 13.2 0.0 0.088 12.2 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Kdo PF06293.14 PSC75250.1 - 0.094 12.1 0.1 0.84 8.9 0.1 2.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Prok-E2_E PF14462.6 PSC75250.1 - 0.12 12.2 0.0 0.81 9.5 0.1 2.1 2 0 0 2 2 2 0 Prokaryotic E2 family E TraG_N PF07916.11 PSC75250.1 - 3 6.6 5.5 7.1 5.4 5.5 1.6 1 0 0 1 1 1 0 TraG-like protein, N-terminal region PUB PF09409.10 PSC75252.1 - 1.3e-13 50.7 0.0 2.4e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 PUB domain UBX PF00789.20 PSC75252.1 - 5.3e-07 29.7 0.0 8.5e-07 29.1 0.0 1.3 1 0 0 1 1 1 1 UBX domain CCDC53 PF10152.9 PSC75252.1 - 2.3 8.6 9.5 1.8 9.0 4.3 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex TFIIA PF03153.13 PSC75252.1 - 6.2 6.7 11.4 0.86 9.5 7.5 1.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2358 PF10184.9 PSC75253.1 - 1.4e-20 73.6 0.0 2.2e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) DUF2358 PF10184.9 PSC75254.1 - 1.4e-20 73.6 0.0 2.2e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) Trypsin PF00089.26 PSC75255.1 - 0.042 13.7 0.5 1.9 8.2 0.0 2.5 2 1 0 2 2 2 0 Trypsin Chorion_3 PF05387.11 PSC75256.1 - 0.079 12.6 1.7 0.1 12.2 1.7 1.2 1 0 0 1 1 1 0 Chorion family 3 Aldo_ket_red PF00248.21 PSC75257.1 - 4.4e-72 242.8 0.0 5.2e-72 242.5 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family RRM_1 PF00076.22 PSC75257.1 - 1.6e-14 53.5 0.0 3e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PSC75257.1 - 0.0019 18.2 0.0 0.0047 17.0 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif Aldo_ket_red PF00248.21 PSC75258.1 - 7.1e-47 160.0 0.0 7.6e-37 127.1 0.0 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family IFT57 PF10498.9 PSC75259.1 - 4.2e-18 65.5 0.0 3.5e-17 62.4 0.0 1.9 1 1 0 1 1 1 1 Intra-flagellar transport protein 57 ATG16 PF08614.11 PSC75259.1 - 0.0019 18.5 6.7 0.0019 18.5 6.7 1.6 2 0 0 2 2 2 1 Autophagy protein 16 (ATG16) Atg14 PF10186.9 PSC75259.1 - 0.081 12.0 1.2 0.098 11.7 1.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4407 PF14362.6 PSC75259.1 - 1.8 7.9 10.6 0.99 8.7 7.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Uds1 PF15456.6 PSC75259.1 - 1.8 8.8 9.7 0.36 11.0 5.7 1.9 2 0 0 2 2 2 0 Up-regulated During Septation LRR_6 PF13516.6 PSC75260.1 - 2.9e-23 79.9 49.1 0.027 14.5 0.1 18.3 22 0 0 22 22 22 10 Leucine Rich repeat LRR_4 PF12799.7 PSC75260.1 - 3.2e-22 78.2 13.4 0.034 14.6 0.1 12.3 8 2 4 13 13 13 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC75260.1 - 1.1e-08 34.8 32.4 1.1 9.1 0.0 11.5 7 2 5 13 13 13 7 Leucine rich repeat F-box PF00646.33 PSC75260.1 - 0.012 15.5 0.0 0.052 13.4 0.0 2.2 1 0 0 1 1 1 0 F-box domain LRR_1 PF00560.33 PSC75260.1 - 2.4 9.0 40.7 29 5.7 0.1 15.3 17 4 0 17 17 17 0 Leucine Rich Repeat AAA PF00004.29 PSC75261.1 - 1.4e-42 145.2 0.0 2.5e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) CRAL_TRIO PF00650.20 PSC75261.1 - 2.8e-17 62.9 0.0 4.6e-17 62.2 0.0 1.3 1 0 0 1 1 1 1 CRAL/TRIO domain Prot_ATP_ID_OB PF16450.5 PSC75261.1 - 1.2e-10 41.2 0.1 2.3e-10 40.2 0.1 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 PSC75261.1 - 4.6e-10 39.1 0.2 2.5e-09 36.8 0.1 2.3 2 0 0 2 2 2 1 AAA+ lid domain AAA_16 PF13191.6 PSC75261.1 - 1e-06 29.2 0.7 0.00073 20.0 0.0 3.6 3 1 1 4 4 4 1 AAA ATPase domain RuvB_N PF05496.12 PSC75261.1 - 1.9e-05 24.5 0.0 6e-05 22.8 0.0 1.8 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 PSC75261.1 - 8.1e-05 22.6 0.0 0.00063 19.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 PSC75261.1 - 0.00012 22.3 0.0 0.00029 21.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 PSC75261.1 - 0.0019 18.5 0.1 0.085 13.1 0.0 2.9 2 1 1 3 3 2 1 AAA domain AAA_18 PF13238.6 PSC75261.1 - 0.0039 17.8 0.0 0.011 16.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain DUF815 PF05673.13 PSC75261.1 - 0.0046 16.2 0.0 0.0083 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 PSC75261.1 - 0.0084 16.5 0.0 0.019 15.3 0.0 1.6 1 0 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 PSC75261.1 - 0.015 15.1 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_28 PF13521.6 PSC75261.1 - 0.017 15.4 0.1 0.39 11.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 PSC75261.1 - 0.017 14.5 0.0 0.039 13.3 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 PSC75261.1 - 0.018 14.3 0.0 0.035 13.3 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain Parvo_NS1 PF01057.17 PSC75261.1 - 0.029 13.4 0.0 0.06 12.4 0.0 1.4 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 PSC75261.1 - 0.033 13.7 0.0 0.079 12.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_3 PF07726.11 PSC75261.1 - 0.034 14.0 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 PSC75261.1 - 0.056 13.6 0.2 0.98 9.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 PSC75261.1 - 0.078 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 PSC75261.1 - 0.09 12.5 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 PSC75261.1 - 0.13 12.0 0.0 0.36 10.5 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain TsaE PF02367.17 PSC75261.1 - 0.13 12.2 0.0 0.4 10.7 0.0 1.7 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NACHT PF05729.12 PSC75261.1 - 0.15 12.0 0.0 0.41 10.5 0.0 1.8 1 0 0 1 1 1 0 NACHT domain PEX11 PF05648.14 PSC75262.1 - 6e-34 117.5 0.1 1.2e-33 116.5 0.1 1.4 1 1 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) HSP33 PF01430.19 PSC75263.1 - 6.5e-66 222.5 0.0 7.9e-66 222.2 0.0 1.1 1 0 0 1 1 1 1 Hsp33 protein Aconitase PF00330.20 PSC75264.1 - 1.3e-79 268.4 0.0 2e-77 261.2 0.0 2.1 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Abhydrolase_1 PF00561.20 PSC75264.1 - 0.0014 18.3 0.0 0.0036 17.0 0.0 1.6 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_4 PF08386.10 PSC75264.1 - 0.021 15.0 0.0 0.054 13.6 0.0 1.6 1 0 0 1 1 1 0 TAP-like protein RP1-2 PF12042.8 PSC75264.1 - 1.5 8.7 4.9 0.23 11.3 1.0 1.6 2 0 0 2 2 2 0 Tubuliform egg casing silk strands structural domain Motile_Sperm PF00635.26 PSC75266.1 - 6.6e-19 67.8 0.0 1.4e-18 66.7 0.0 1.5 1 0 0 1 1 1 1 MSP (Major sperm protein) domain ASH PF15780.5 PSC75266.1 - 0.0065 16.6 0.0 0.014 15.6 0.0 1.5 1 0 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin ORC3_N PF07034.11 PSC75267.1 - 1.1e-39 136.4 0.0 6.5e-39 134.0 0.0 2.1 1 1 0 1 1 1 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 PSC75267.1 - 7.1e-22 78.0 0.0 7.1e-22 78.0 0.0 3.9 3 1 0 3 3 3 1 Origin recognition complex winged helix C-terminal DUF3040 PF11239.8 PSC75267.1 - 4.4 7.6 6.4 1 9.7 0.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) Draxin PF15550.6 PSC75267.1 - 8.9 6.1 10.1 0.11 12.4 0.7 2.3 3 0 0 3 3 3 0 Draxin DnaJ PF00226.31 PSC75268.1 - 6.9e-15 54.9 0.2 6.9e-15 54.9 0.2 2.5 3 0 0 3 3 3 1 DnaJ domain SET PF00856.28 PSC75269.1 - 5.2e-21 75.8 0.1 5.2e-21 75.8 0.1 3.0 3 2 0 3 3 3 1 SET domain SET PF00856.28 PSC75270.1 - 5.7e-21 75.6 0.1 5.7e-21 75.6 0.1 3.2 3 3 0 3 3 3 1 SET domain SBF PF01758.16 PSC75271.1 - 1.8e-40 138.7 14.2 4.1e-40 137.6 14.2 1.6 1 0 0 1 1 1 1 Sodium Bile acid symporter family SBF_like PF13593.6 PSC75271.1 - 6.3e-19 68.4 20.8 9.8e-19 67.8 20.8 1.2 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) LRR_4 PF12799.7 PSC75271.1 - 6.2e-05 23.3 4.1 0.012 16.0 0.0 4.7 5 1 1 6 6 6 1 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PSC75271.1 - 0.0074 16.3 0.6 1.7 8.9 0.0 3.5 3 0 0 3 3 3 1 Leucine Rich repeat Pex2_Pex12 PF04757.14 PSC75272.1 - 1.5e-36 126.1 0.1 1.8e-36 125.8 0.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 PSC75272.1 - 5.1e-05 23.0 1.0 7.9e-05 22.4 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC75272.1 - 0.00088 19.1 0.8 0.0014 18.4 0.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC75272.1 - 0.0027 17.7 3.7 0.0044 17.0 3.7 1.3 1 0 0 1 1 1 1 RING-type zinc-finger LRV_FeS PF05484.11 PSC75272.1 - 0.03 14.3 0.3 0.06 13.4 0.3 1.4 1 0 0 1 1 1 0 LRV protein FeS4 cluster zf-C3HC4 PF00097.25 PSC75272.1 - 0.048 13.6 0.5 0.072 13.0 0.5 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC75272.1 - 0.065 13.6 2.2 0.16 12.4 2.2 1.6 1 1 0 1 1 1 0 Ring finger domain NeA_P2 PF12312.8 PSC75272.1 - 0.082 12.3 0.8 0.18 11.3 0.2 1.8 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein zf-RING_6 PF14835.6 PSC75272.1 - 0.13 12.2 0.3 0.24 11.3 0.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 PSC75272.1 - 0.22 11.5 1.1 0.38 10.8 1.1 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PSC75272.1 - 0.4 10.9 2.4 0.66 10.2 2.4 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING VIR_N PF15912.5 PSC75272.1 - 0.41 10.2 0.8 0.8 9.2 0.1 1.7 2 0 0 2 2 2 0 Virilizer, N-terminal zf-RING_4 PF14570.6 PSC75272.1 - 0.65 9.8 3.3 4 7.3 0.2 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PRIMA1 PF16101.5 PSC75272.1 - 5 7.2 11.2 26 4.9 6.1 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 PSC75272.1 - 5.3 6.4 5.9 3.7 6.9 1.8 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Pex2_Pex12 PF04757.14 PSC75273.1 - 1.5e-36 126.1 0.1 1.8e-36 125.8 0.1 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.6 PSC75273.1 - 5.1e-05 23.0 1.0 7.9e-05 22.4 1.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC75273.1 - 0.00088 19.1 0.8 0.0014 18.4 0.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC75273.1 - 0.0027 17.7 3.7 0.0044 17.0 3.7 1.3 1 0 0 1 1 1 1 RING-type zinc-finger LRV_FeS PF05484.11 PSC75273.1 - 0.03 14.3 0.3 0.06 13.4 0.3 1.4 1 0 0 1 1 1 0 LRV protein FeS4 cluster zf-C3HC4 PF00097.25 PSC75273.1 - 0.048 13.6 0.5 0.072 13.0 0.5 1.2 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC75273.1 - 0.065 13.6 2.2 0.16 12.4 2.2 1.6 1 1 0 1 1 1 0 Ring finger domain NeA_P2 PF12312.8 PSC75273.1 - 0.082 12.3 0.8 0.18 11.3 0.2 1.8 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein zf-RING_6 PF14835.6 PSC75273.1 - 0.13 12.2 0.3 0.24 11.3 0.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 PSC75273.1 - 0.22 11.5 1.1 0.38 10.8 1.1 1.3 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 PSC75273.1 - 0.4 10.9 2.4 0.66 10.2 2.4 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING VIR_N PF15912.5 PSC75273.1 - 0.41 10.2 0.8 0.8 9.2 0.1 1.7 2 0 0 2 2 2 0 Virilizer, N-terminal zf-RING_4 PF14570.6 PSC75273.1 - 0.65 9.8 3.3 4 7.3 0.2 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain PRIMA1 PF16101.5 PSC75273.1 - 5 7.2 11.2 26 4.9 6.1 2.4 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 CAP_N PF01213.19 PSC75273.1 - 5.3 6.4 5.9 3.7 6.9 1.8 2.0 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal p450 PF00067.22 PSC75274.1 - 2.4e-59 201.3 0.0 6.8e-59 199.8 0.0 1.7 2 0 0 2 2 2 1 Cytochrome P450 Sulfotransfer_2 PF03567.14 PSC75274.1 - 5.4e-15 56.0 0.0 1e-14 55.1 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase family 2-oxoacid_dh PF00198.23 PSC75275.1 - 6.1e-68 228.7 0.0 9.3e-68 228.1 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 PSC75275.1 - 7.7e-18 64.1 2.9 2e-17 62.7 2.9 1.8 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 PSC75275.1 - 1.9e-15 56.9 0.3 6.6e-15 55.2 0.3 2.1 1 0 0 1 1 1 1 e3 binding domain GCV_H PF01597.19 PSC75275.1 - 0.14 12.1 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 Glycine cleavage H-protein DUF4097 PF13349.6 PSC75276.1 - 4.7e-11 42.5 0.3 1.4e-07 31.2 0.2 2.2 1 1 1 2 2 2 2 Putative adhesin ENOD40 PF08247.11 PSC75277.1 - 0.15 12.1 1.6 0.34 11.0 1.6 1.5 1 0 0 1 1 1 0 ENOD40 protein DUF588 PF04535.12 PSC75277.1 - 1.9 8.3 14.0 5.5 6.8 0.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF588) adh_short_C2 PF13561.6 PSC75278.1 - 3.6e-66 223.1 8.9 4.5e-66 222.8 8.9 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PSC75278.1 - 3e-53 180.2 5.7 3.5e-53 180.0 5.7 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PSC75278.1 - 4.7e-13 49.5 3.9 8.6e-13 48.6 3.9 1.3 1 0 0 1 1 1 1 KR domain PBP_like PF12727.7 PSC75278.1 - 0.32 10.1 2.6 0.17 11.0 0.2 1.8 2 0 0 2 2 2 0 PBP superfamily domain Peptidase_C69 PF03577.15 PSC75279.1 - 5.5e-08 32.1 0.0 7.4e-08 31.7 0.0 1.1 1 0 0 1 1 1 1 Peptidase family C69 GrpE PF01025.19 PSC75280.1 - 6.7e-46 156.0 2.9 1.2e-45 155.2 2.9 1.4 1 1 0 1 1 1 1 GrpE Peptidase_S46 PF10459.9 PSC75280.1 - 0.0051 15.5 3.8 0.0059 15.3 3.8 1.1 1 0 0 1 1 1 1 Peptidase S46 Goodbye PF17109.5 PSC75280.1 - 0.025 15.0 0.8 0.048 14.1 0.8 1.4 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain PIN_8 PF18476.1 PSC75280.1 - 0.13 12.1 1.4 0.18 11.6 1.4 1.3 1 0 0 1 1 1 0 PIN like domain YlqD PF11068.8 PSC75280.1 - 2.2 8.7 8.3 3.5 8.0 8.3 1.3 1 0 0 1 1 1 0 YlqD protein E2F_TDP PF02319.20 PSC75281.1 - 8.1e-22 77.1 0.0 1.7e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DP PF08781.10 PSC75281.1 - 4.2e-16 59.1 0.1 4.2e-16 59.1 0.1 2.4 2 0 0 2 2 2 1 Transcription factor DP CAML PF14963.6 PSC75281.1 - 0.72 9.9 3.7 2.1 8.4 3.7 1.7 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DUF775 PF05603.12 PSC75281.1 - 1.1 8.7 19.1 0.049 13.1 10.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF775) BORG_CEP PF14957.6 PSC75281.1 - 6.4 7.9 10.8 9.1 7.5 6.9 2.6 2 0 0 2 2 2 0 Cdc42 effector RR_TM4-6 PF06459.12 PSC75281.1 - 6.6 6.5 20.2 2.8 7.7 14.9 2.3 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 DnaJ PF00226.31 PSC75282.1 - 3.6e-19 68.6 0.1 6.4e-19 67.9 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain MS_channel PF00924.18 PSC75282.1 - 2.3e-18 66.5 0.2 3.5e-18 65.9 0.2 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel Sporozoite_P67 PF05642.11 PSC75282.1 - 9.4 4.2 6.9 1.1 7.3 0.3 2.0 2 0 0 2 2 2 0 Sporozoite P67 surface antigen LytR_C PF13399.6 PSC75283.1 - 0.065 14.2 0.5 0.66 11.0 0.0 2.8 2 1 1 3 3 3 0 LytR cell envelope-related transcriptional attenuator GTP_EFTU PF00009.27 PSC75285.1 - 1.9e-45 154.8 0.1 4.2e-45 153.7 0.1 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Redoxin PF08534.10 PSC75285.1 - 1.7e-13 50.6 0.0 4.4e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 PSC75285.1 - 1.9e-13 50.4 0.0 3.3e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 AhpC/TSA family GTP_EFTU_D2 PF03144.25 PSC75285.1 - 3.1e-12 46.7 1.2 2.1e-11 44.0 0.6 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 PSC75285.1 - 6.7e-12 45.7 0.1 3.7e-11 43.3 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain Thioredoxin_8 PF13905.6 PSC75285.1 - 6.2e-10 39.3 0.0 1.5e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 PSC75285.1 - 6e-08 32.6 0.0 3.7e-07 30.1 0.0 2.2 1 1 1 2 2 2 1 Thioredoxin MMR_HSR1 PF01926.23 PSC75285.1 - 1.9e-05 24.7 0.0 0.0062 16.6 0.0 3.3 3 1 0 3 3 3 1 50S ribosome-binding GTPase SAP PF02037.27 PSC75285.1 - 4.2e-05 23.2 0.8 0.00012 21.8 0.1 2.2 2 0 0 2 2 2 1 SAP domain Rho_N PF07498.12 PSC75285.1 - 0.0038 17.1 0.0 0.0077 16.1 0.0 1.5 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain GTP_EFTU_D4 PF14578.6 PSC75285.1 - 0.0043 16.9 0.7 0.019 14.8 0.7 2.2 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Armet PF10208.9 PSC75285.1 - 0.042 13.8 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 Degradation arginine-rich protein for mis-folding HeH PF12949.7 PSC75285.1 - 0.14 11.9 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 HeH/LEM domain KTI12 PF08433.10 PSC75285.1 - 0.19 11.1 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 ERCC4 PF02732.15 PSC75286.1 - 1.3e-18 67.7 0.0 2.2e-18 67.0 0.0 1.4 1 0 0 1 1 1 1 ERCC4 domain Sugar_tr PF00083.24 PSC75287.1 - 4.2e-91 306.1 16.6 6.8e-91 305.4 13.4 2.4 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_1 PF07690.16 PSC75287.1 - 1.6e-16 60.2 34.7 1.6e-16 60.2 34.7 2.8 1 1 0 2 2 2 1 Major Facilitator Superfamily F-box-like PF12937.7 PSC75287.1 - 0.0008 19.3 0.1 0.0018 18.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like MFS_1 PF07690.16 PSC75289.1 - 4.3e-42 144.3 45.6 4.3e-42 144.3 45.6 1.9 1 1 1 2 2 2 1 Major Facilitator Superfamily CAP_N PF01213.19 PSC75290.1 - 2.2 7.7 4.9 4 6.8 4.9 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal MS_channel PF00924.18 PSC75291.1 - 5.3e-17 62.0 1.7 1.2e-16 61.0 1.7 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel Ank_4 PF13637.6 PSC75291.1 - 0.027 15.1 0.9 0.097 13.3 0.1 2.4 3 0 0 3 3 3 0 Ankyrin repeats (many copies) MAPEG PF01124.18 PSC75293.1 - 0.0038 17.1 0.1 0.014 15.3 0.1 2.0 1 0 0 1 1 1 1 MAPEG family Pex14_N PF04695.13 PSC75293.1 - 0.02 15.6 18.5 0.53 10.9 0.7 3.2 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Sulfotransfer_3 PF13469.6 PSC75294.1 - 0.00011 22.6 0.2 0.00011 22.6 0.2 4.5 2 2 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PSC75294.1 - 0.0063 16.0 0.0 0.011 15.2 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase domain GREB1 PF15782.5 PSC75294.1 - 6.3 3.8 27.3 8.9 3.3 27.3 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LSM PF01423.22 PSC75295.1 - 3.6e-17 61.8 0.1 5.4e-17 61.2 0.1 1.2 1 0 0 1 1 1 1 LSM domain zf-CCCH PF00642.24 PSC75295.1 - 5.1e-16 58.1 14.1 1.5e-08 34.3 2.0 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PSC75295.1 - 3.4e-08 33.3 15.7 3.8e-05 23.6 4.0 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_4 PF18044.1 PSC75295.1 - 6.9e-06 25.7 2.5 6.9e-06 25.7 2.5 2.5 2 1 0 2 2 2 1 CCCH-type zinc finger Torus PF16131.5 PSC75295.1 - 0.026 15.2 9.4 0.046 14.4 0.2 2.2 2 0 0 2 2 2 0 Torus domain zf-CCCH_2 PF14608.6 PSC75295.1 - 0.042 14.3 1.1 0.042 14.3 1.1 2.3 2 0 0 2 2 2 0 RNA-binding, Nab2-type zinc finger DDE_Tnp_1_6 PF13751.6 PSC75295.1 - 0.062 13.5 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain Hfq PF17209.3 PSC75295.1 - 0.067 12.9 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Hfq protein Elong_Iki1 PF10483.9 PSC75296.1 - 6.3e-11 42.3 1.7 3.2e-10 40.0 0.0 2.5 2 1 0 2 2 2 1 Elongator subunit Iki1 TFIIA PF03153.13 PSC75296.1 - 0.0081 16.2 24.5 0.014 15.4 24.5 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 PSC75296.1 - 0.34 11.0 0.0 0.34 11.0 0.0 3.5 2 2 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Pex14_N PF04695.13 PSC75296.1 - 0.37 11.4 19.8 0.94 10.1 19.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ndc1_Nup PF09531.10 PSC75296.1 - 9.4 4.8 6.9 13 4.3 6.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Bestrophin PF01062.21 PSC75297.1 - 2.2e-28 99.5 0.1 3.2e-28 99.0 0.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel CN_hydrolase PF00795.22 PSC75297.1 - 3e-10 39.9 0.1 1.5e-06 27.8 0.1 2.9 2 1 0 2 2 2 2 Carbon-nitrogen hydrolase F-box-like PF12937.7 PSC75298.1 - 2.4e-05 24.1 0.0 5.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PSC75298.1 - 0.00041 20.2 0.0 0.00068 19.5 0.0 1.4 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 PSC75299.1 - 2.6e-05 24.0 0.0 5.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PSC75299.1 - 0.0004 20.2 0.0 0.00066 19.5 0.0 1.4 1 0 0 1 1 1 1 F-box domain PDCD2_C PF04194.13 PSC75300.1 - 2e-26 93.2 0.0 2.6e-26 92.7 0.0 1.2 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain DUF1631 PF07793.11 PSC75300.1 - 5.3 5.3 7.0 7.7 4.8 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) RNA_pol_A_bac PF01000.26 PSC75301.1 - 7.6e-25 87.5 0.0 1.8e-24 86.3 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain DUF4187 PF13821.6 PSC75301.1 - 1.3e-18 66.5 1.0 2.9e-18 65.4 1.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) RNA_pol_L PF01193.24 PSC75301.1 - 3.2e-18 64.9 0.0 4.8e-18 64.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain G-patch PF01585.23 PSC75301.1 - 7.6e-10 38.5 0.5 1.3e-09 37.8 0.5 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 PSC75301.1 - 0.00068 19.7 0.6 0.0013 18.7 0.6 1.5 1 0 0 1 1 1 1 G-patch domain adh_short_C2 PF13561.6 PSC75302.1 - 1.9e-51 174.9 8.1 2.7e-51 174.4 8.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PSC75302.1 - 5.6e-37 127.1 1.8 7.5e-37 126.7 1.8 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PSC75302.1 - 1.5e-09 38.0 1.8 3e-09 37.1 1.8 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PSC75302.1 - 0.0001 21.9 0.2 0.00016 21.3 0.2 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family CitMHS PF03600.16 PSC75304.1 - 6.6e-39 133.9 37.3 6.6e-39 133.9 37.3 1.9 2 0 0 2 2 2 1 Citrate transporter Morc6_S5 PF17942.1 PSC75304.1 - 1.8e-16 60.4 0.0 3e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Morc6 ribosomal protein S5 domain 2-like CitMHS_2 PF16980.5 PSC75304.1 - 6.2e-07 28.4 15.8 0.00049 18.9 4.3 2.4 2 1 0 2 2 2 2 Putative citrate transport Exo_endo_phos PF03372.23 PSC75305.1 - 2e-27 96.2 0.1 2.9e-27 95.7 0.1 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family zf-C6H2 PF15801.5 PSC75305.1 - 1.7e-05 25.0 10.0 3.5e-05 24.0 10.0 1.5 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 PSC75305.1 - 0.017 15.2 9.7 0.034 14.2 9.7 1.5 1 0 0 1 1 1 0 MYND finger Ribosomal_L31e PF01198.19 PSC75306.1 - 1.7e-37 127.5 3.1 2e-37 127.3 3.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Mrr_cat PF04471.12 PSC75306.1 - 0.082 12.9 1.1 0.17 12.0 0.9 1.6 1 1 1 2 2 2 0 Restriction endonuclease Pkinase_Tyr PF07714.17 PSC75307.1 - 8.2e-08 31.8 0.0 3.8e-06 26.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PSC75307.1 - 2.6e-07 30.3 0.0 2.4e-05 23.8 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain PEP-CTERM PF07589.11 PSC75307.1 - 0.58 10.3 3.3 2.6 8.2 3.3 2.2 1 0 0 1 1 1 0 PEP-CTERM motif Cnd1 PF12717.7 PSC75308.1 - 0.0011 19.0 0.0 0.12 12.5 0.0 2.5 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 PSC75308.1 - 0.046 14.0 0.2 0.046 14.0 0.2 7.4 8 0 0 8 8 8 0 HEAT repeat Surfac_D-trimer PF09006.11 PSC75308.1 - 0.061 13.2 0.0 21 5.1 0.0 2.8 3 0 0 3 3 3 0 Lung surfactant protein D coiled-coil trimerisation NTP_transferase PF00483.23 PSC75310.1 - 1e-39 136.7 0.0 1.6e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Nucleotidyl transferase Ribosomal_L11_N PF03946.14 PSC75310.1 - 3.2e-20 71.7 0.1 9.4e-20 70.2 0.1 1.9 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain rve PF00665.26 PSC75310.1 - 2.3e-18 66.5 0.0 5.2e-18 65.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Ribosomal_L11 PF00298.19 PSC75310.1 - 9.1e-15 54.9 0.1 2.5e-14 53.5 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain rve_3 PF13683.6 PSC75310.1 - 0.015 15.0 0.0 0.046 13.5 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain DUF4954 PF16314.5 PSC75310.1 - 0.02 13.0 1.3 0.67 8.0 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4954) Hexapep PF00132.24 PSC75310.1 - 0.34 10.7 16.4 0.29 10.9 0.7 4.3 4 1 1 5 5 5 0 Bacterial transferase hexapeptide (six repeats) Amidohydro_1 PF01979.20 PSC75311.1 - 2.4e-29 102.8 1.5 2.9e-29 102.5 1.5 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 PSC75311.1 - 6.4e-12 45.7 6.8 6.5e-05 22.6 2.6 3.3 2 1 0 2 2 2 2 Amidohydrolase family AP_endonuc_2 PF01261.24 PSC75311.1 - 0.0026 17.2 0.2 0.0046 16.4 0.2 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel Ank_2 PF12796.7 PSC75312.1 - 1.2e-10 41.9 0.0 6.3e-05 23.5 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC75312.1 - 1.4e-10 41.2 0.2 1.3e-07 31.8 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 PSC75312.1 - 1.6e-09 37.8 0.0 1.2e-06 28.7 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 PSC75312.1 - 1.6e-09 38.1 0.0 0.00032 21.2 0.1 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC75312.1 - 1.6e-07 31.0 0.1 3.1e-05 24.0 0.0 3.5 4 0 0 4 4 4 1 Ankyrin repeat DUF4953 PF16313.5 PSC75312.1 - 0.1 11.8 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Met-zincin Bestrophin PF01062.21 PSC75313.1 - 1.6e-34 119.7 0.0 1.5e-18 67.3 0.0 2.1 1 1 1 2 2 2 2 Bestrophin, RFP-TM, chloride channel UL42 PF17638.2 PSC75313.1 - 0.023 14.7 1.1 0.045 13.7 0.4 1.8 2 0 0 2 2 2 0 HCMV UL42 Swi3 PF07962.12 PSC75314.1 - 5.1e-17 61.6 0.1 7.4e-17 61.1 0.1 1.2 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 DUF4366 PF14283.6 PSC75314.1 - 4.5 7.3 14.5 38 4.3 0.3 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) SKA2 PF16740.5 PSC75315.1 - 1.3e-21 76.4 1.1 2e-21 75.8 1.1 1.2 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 2 Sec8_exocyst PF04048.14 PSC75315.1 - 0.016 15.1 0.3 0.23 11.3 0.0 2.0 1 1 0 2 2 2 0 Sec8 exocyst complex component specific domain NYD-SP28 PF14772.6 PSC75315.1 - 0.049 13.7 4.8 0.33 11.0 4.8 2.1 1 1 0 1 1 1 0 Sperm tail HIP1_clath_bdg PF16515.5 PSC75315.1 - 0.054 14.1 6.4 0.21 12.2 5.7 2.1 1 1 1 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 OmpH PF03938.14 PSC75315.1 - 0.11 12.8 8.1 0.067 13.5 3.2 2.0 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) GrpE PF01025.19 PSC75315.1 - 0.22 11.2 2.4 0.25 11.0 1.1 1.6 1 1 1 2 2 2 0 GrpE TMF_TATA_bd PF12325.8 PSC75315.1 - 0.71 10.1 6.4 4.7 7.5 4.9 2.4 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Spectrin PF00435.21 PSC75315.1 - 0.75 10.3 6.5 4.2 7.9 4.7 2.6 2 1 1 3 3 3 0 Spectrin repeat Zein-binding PF04576.15 PSC75315.1 - 0.81 10.0 8.2 0.098 13.0 3.7 1.8 2 0 0 2 2 2 0 Zein-binding Spc7 PF08317.11 PSC75315.1 - 3.1 6.6 7.3 1.9 7.3 4.8 1.7 1 1 0 2 2 2 0 Spc7 kinetochore protein DUF4164 PF13747.6 PSC75315.1 - 3.3 8.1 9.3 0.67 10.3 4.7 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) TPR_12 PF13424.6 PSC75316.1 - 5.2e-46 154.8 40.4 6.4e-14 52.0 1.3 7.1 4 2 3 7 7 7 5 Tetratricopeptide repeat TPR_10 PF13374.6 PSC75316.1 - 9.8e-37 123.8 43.5 7.6e-08 32.0 0.5 10.2 9 0 0 9 9 9 6 Tetratricopeptide repeat DHHC PF01529.20 PSC75316.1 - 5.9e-28 97.6 0.8 5.9e-28 97.6 0.8 1.7 2 0 0 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 PSC75316.1 - 5.8e-25 87.7 0.1 6.7e-09 36.2 0.0 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC75316.1 - 1.1e-22 79.8 2.2 2.7e-06 27.5 0.0 5.3 3 1 1 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC75316.1 - 9.6e-20 70.7 1.4 6e-08 33.1 0.0 5.5 2 1 4 6 6 5 5 Ankyrin repeats (many copies) Ank PF00023.30 PSC75316.1 - 1.3e-16 60.2 1.6 0.0015 18.8 0.0 5.8 5 0 0 5 5 5 4 Ankyrin repeat TPR_2 PF07719.17 PSC75316.1 - 4.1e-16 57.7 23.3 0.0032 17.5 1.0 7.9 7 0 0 7 7 6 4 Tetratricopeptide repeat Ank_3 PF13606.6 PSC75316.1 - 2.6e-15 55.0 0.2 0.0097 16.4 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat TPR_7 PF13176.6 PSC75316.1 - 8.4e-14 50.5 21.9 5e-05 23.0 0.5 7.4 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 PSC75316.1 - 2.6e-12 46.0 17.3 0.00016 21.3 0.6 5.9 7 0 0 7 7 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 PSC75316.1 - 1e-11 44.1 12.5 0.027 14.7 0.0 6.1 7 0 0 7 7 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 PSC75316.1 - 1.5e-07 31.8 3.0 0.00028 21.3 0.1 7.1 4 1 2 8 8 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 PSC75316.1 - 5.5e-05 22.7 7.7 5.5e-05 22.7 7.7 5.2 2 2 2 4 4 3 3 MalT-like TPR region TPR_16 PF13432.6 PSC75316.1 - 0.00094 19.8 1.1 0.00094 19.8 1.1 9.5 8 4 2 10 10 6 3 Tetratricopeptide repeat DUF2225 PF09986.9 PSC75316.1 - 0.19 11.4 0.2 0.43 10.3 0.2 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TFIIA PF03153.13 PSC75316.1 - 3.9 7.4 19.3 4.5 7.2 6.1 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RETICULATA-like PF11891.8 PSC75317.1 - 1.5e-55 187.8 0.0 3.6e-55 186.5 0.0 1.7 1 0 0 1 1 1 1 Protein RETICULATA-related rve PF00665.26 PSC75317.1 - 1.6e-18 67.0 0.0 5.5e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 Integrase core domain Sacchrp_dh_NADP PF03435.18 PSC75317.1 - 1.4e-16 60.9 0.8 2.7e-16 60.0 0.1 2.0 2 0 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 PSC75317.1 - 1.3e-05 25.2 0.7 1.3e-05 25.2 0.7 2.0 2 0 0 2 2 2 1 NAD(P)H-binding NmrA PF05368.13 PSC75317.1 - 0.0073 15.9 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 NmrA-like family rve_3 PF13683.6 PSC75317.1 - 0.02 14.6 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain Ldh_1_N PF00056.23 PSC75317.1 - 0.027 14.6 0.0 0.054 13.6 0.0 1.5 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Epimerase PF01370.21 PSC75317.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Glyco_hydro_16 PF00722.21 PSC75318.1 - 6.6e-17 61.5 0.0 1e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 FA_desaturase PF00487.24 PSC75319.1 - 7.9e-18 65.2 63.4 3.2e-12 46.8 27.8 3.3 2 1 1 3 3 3 3 Fatty acid desaturase Mcl1_mid PF12341.8 PSC75319.1 - 0.004 16.5 0.0 13 5.0 0.0 3.3 3 0 0 3 3 3 3 Minichromosome loss protein, Mcl1, middle region SpecificRecomb PF10136.9 PSC75319.1 - 0.37 9.0 1.6 5.9 5.1 0.2 2.0 2 0 0 2 2 2 0 Site-specific recombinase DUF4131 PF13567.6 PSC75319.1 - 5.2 6.7 8.2 0.71 9.5 1.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Myb_DNA-binding PF00249.31 PSC75320.1 - 0.17 12.1 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 PSC75321.1 - 0.17 12.1 0.0 0.33 11.2 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Methyltrans_RNA PF04452.14 PSC75322.1 - 1.1e-40 139.4 0.0 1e-22 80.6 0.0 2.1 2 0 0 2 2 2 2 RNA methyltransferase PAN_4 PF14295.6 PSC75322.1 - 6.4e-08 32.4 0.8 6.4e-08 32.4 0.8 3.0 4 0 0 4 4 4 1 PAN domain UPF0506 PF11703.8 PSC75322.1 - 2.8 8.4 33.3 0.18 12.2 11.6 3.3 2 1 1 3 3 3 0 UPF0506 Methyltrans_RNA PF04452.14 PSC75323.1 - 1.1e-40 139.4 0.0 1e-22 80.6 0.0 2.1 2 0 0 2 2 2 2 RNA methyltransferase PAN_4 PF14295.6 PSC75323.1 - 6.4e-08 32.4 0.8 6.4e-08 32.4 0.8 3.0 4 0 0 4 4 4 1 PAN domain UPF0506 PF11703.8 PSC75323.1 - 2.8 8.4 33.3 0.18 12.2 11.6 3.3 2 1 1 3 3 3 0 UPF0506 Aminotran_5 PF00266.19 PSC75324.1 - 7.2e-22 77.8 0.1 3e-21 75.8 0.0 1.9 2 0 0 2 2 2 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 PSC75324.1 - 0.073 12.4 3.7 0.15 11.3 3.7 1.4 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family Ysc84 PF04366.12 PSC75324.1 - 2.1 8.1 10.0 1.3 8.7 2.1 3.8 3 0 0 3 3 3 0 Las17-binding protein actin regulator Nucleoside_tran PF01733.18 PSC75325.1 - 9e-46 156.7 4.3 1.4e-27 96.9 3.9 2.6 2 1 0 2 2 2 2 Nucleoside transporter Pkinase PF00069.25 PSC75327.1 - 2.4e-62 210.7 0.0 3.6e-62 210.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Aminotran_1_2 PF00155.21 PSC75327.1 - 3.5e-40 138.3 0.0 6.5e-40 137.4 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Pkinase_Tyr PF07714.17 PSC75327.1 - 3.6e-27 95.3 0.0 5.5e-27 94.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC75327.1 - 3e-06 26.8 0.0 6.2e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PSC75327.1 - 3.1e-06 26.7 0.0 6.2e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 PSC75327.1 - 0.019 14.6 0.0 0.036 13.7 0.0 1.4 1 0 0 1 1 1 0 RIO1 family Pkinase_fungal PF17667.1 PSC75327.1 - 0.12 11.1 0.0 0.12 11.1 0.0 1.6 2 0 0 2 2 2 0 Fungal protein kinase AAA PF00004.29 PSC75328.1 - 7.2e-34 117.1 0.0 1.2e-33 116.3 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PSC75328.1 - 2.2e-09 37.0 1.4 7.9e-09 35.2 1.4 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 PSC75328.1 - 0.00052 20.0 0.0 0.0024 17.9 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 PSC75328.1 - 0.00092 19.4 0.0 0.0018 18.5 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PSC75328.1 - 0.0013 19.0 0.1 0.13 12.5 0.0 2.5 1 1 1 2 2 2 1 AAA domain NACHT PF05729.12 PSC75328.1 - 0.0019 18.1 0.1 0.9 9.4 0.1 2.3 1 1 1 2 2 2 2 NACHT domain Viral_helicase1 PF01443.18 PSC75328.1 - 0.0064 16.3 0.0 0.0093 15.7 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_2 PF07724.14 PSC75328.1 - 0.011 15.8 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 PSC75328.1 - 0.015 15.7 7.3 0.36 11.2 7.3 3.1 1 1 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.6 PSC75328.1 - 0.13 12.5 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 PSC75328.1 - 0.13 11.5 0.0 0.18 11.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 PSC75328.1 - 0.23 11.5 0.0 0.38 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain Mito_carr PF00153.27 PSC75329.1 - 4.4e-55 183.6 2.3 9.9e-18 63.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Rieske PF00355.26 PSC75330.1 - 2e-07 30.9 0.1 3.3e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain Rieske_2 PF13806.6 PSC75330.1 - 0.036 14.0 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 Rieske-like [2Fe-2S] domain DUF2358 PF10184.9 PSC75331.1 - 1.1e-16 61.1 0.0 1.7e-08 34.7 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2358) GTP1_OBG PF01018.22 PSC75331.1 - 0.054 13.1 2.6 0.093 12.3 2.6 1.3 1 0 0 1 1 1 0 GTP1/OBG LRR_6 PF13516.6 PSC75332.1 - 8.5e-19 66.0 4.6 0.03 14.4 0.0 8.6 8 0 0 8 8 8 4 Leucine Rich repeat WPP PF13943.6 PSC75332.1 - 3.4e-07 30.6 0.6 5.1e-06 26.8 0.1 2.5 2 0 0 2 2 2 1 WPP domain LRR_4 PF12799.7 PSC75332.1 - 2.8e-05 24.4 0.9 27 5.4 0.0 5.5 4 1 1 5 5 5 1 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 PSC75332.1 - 3.1e-05 23.9 0.2 95 4.2 0.0 6.0 8 0 0 8 8 8 0 Leucine Rich Repeat LRR_8 PF13855.6 PSC75332.1 - 4.6e-05 23.1 0.7 3.1 7.6 0.0 5.9 6 1 0 6 6 6 1 Leucine rich repeat LRR_2 PF07723.13 PSC75332.1 - 0.028 15.1 0.0 0.14 12.9 0.0 2.3 2 0 0 2 2 2 0 Leucine Rich Repeat Exo_endo_phos PF03372.23 PSC75333.1 - 9.3e-09 35.1 1.1 3.7e-08 33.2 1.1 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PEN-2 PF10251.9 PSC75333.1 - 0.028 14.8 2.5 0.059 13.8 2.5 1.4 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase Exo_endo_phos PF03372.23 PSC75334.1 - 9.3e-09 35.1 1.1 3.7e-08 33.2 1.1 2.1 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family PEN-2 PF10251.9 PSC75334.1 - 0.028 14.8 2.5 0.059 13.8 2.5 1.4 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase CAP_GLY PF01302.25 PSC75335.1 - 1.5e-18 66.6 0.1 2.7e-18 65.7 0.1 1.5 1 0 0 1 1 1 1 CAP-Gly domain LRR_4 PF12799.7 PSC75335.1 - 2.2e-16 59.7 0.0 2.2e-06 27.9 0.0 4.4 4 0 0 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC75335.1 - 1.3e-10 40.8 5.9 2.1e-05 24.2 0.2 4.1 4 1 1 5 5 5 2 Leucine rich repeat LRR_9 PF14580.6 PSC75335.1 - 3.2e-08 33.3 0.0 6e-05 22.6 0.0 3.2 2 1 0 3 3 3 1 Leucine-rich repeat Ubiquitin_2 PF14560.6 PSC75335.1 - 1.1e-06 29.0 0.0 2.2e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain LRR_6 PF13516.6 PSC75335.1 - 0.0002 21.1 1.6 2.1 8.6 0.0 4.4 4 0 0 4 4 4 2 Leucine Rich repeat zf-MYND PF01753.18 PSC75335.1 - 0.013 15.5 0.8 0.013 15.5 0.8 3.0 2 1 0 2 2 2 0 MYND finger LRR_1 PF00560.33 PSC75335.1 - 0.031 14.8 4.4 38 5.4 0.0 5.9 6 1 0 6 6 6 0 Leucine Rich Repeat NAD_binding_10 PF13460.6 PSC75336.1 - 3.7e-32 111.7 0.0 4.4e-32 111.5 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding DapB_N PF01113.20 PSC75336.1 - 2.3e-05 24.5 0.1 3.8e-05 23.8 0.1 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Epimerase PF01370.21 PSC75336.1 - 8.3e-05 22.2 0.0 0.0003 20.3 0.0 1.9 2 2 0 2 2 2 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PSC75336.1 - 0.0049 15.9 0.0 0.011 14.8 0.0 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 PSC75336.1 - 0.012 14.7 0.1 1.3 8.1 0.0 2.1 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein NmrA PF05368.13 PSC75336.1 - 0.026 14.1 0.0 0.13 11.7 0.0 2.2 1 1 0 1 1 1 0 NmrA-like family Semialdhyde_dh PF01118.24 PSC75336.1 - 0.18 12.2 0.1 0.38 11.2 0.1 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Thioredoxin PF00085.20 PSC75337.1 - 1.7e-18 66.5 0.0 2.3e-18 66.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Glutaredoxin PF00462.24 PSC75337.1 - 0.00042 20.5 0.0 0.29 11.4 0.0 2.2 2 0 0 2 2 2 2 Glutaredoxin Thioredoxin_9 PF14595.6 PSC75337.1 - 0.00066 19.4 0.0 0.00087 19.1 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.21 PSC75337.1 - 0.0099 15.8 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 PSC75337.1 - 0.025 15.0 0.0 0.054 13.9 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin_7 PF13899.6 PSC75337.1 - 0.025 14.7 0.0 0.045 13.9 0.0 1.6 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_8 PF13905.6 PSC75337.1 - 0.2 12.0 0.0 0.38 11.1 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin-like Lipase_3 PF01764.25 PSC75338.1 - 9.3e-13 48.3 0.0 2.6e-12 46.8 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) Hydrolase_4 PF12146.8 PSC75338.1 - 0.024 13.9 0.9 0.13 11.5 0.1 2.1 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Anillin_N PF16018.5 PSC75338.1 - 5.7 7.6 7.9 2.6 8.7 0.8 2.4 2 0 0 2 2 2 0 Anillin N-terminus RINGv PF12906.7 PSC75339.1 - 2.7e-11 43.4 6.6 4.5e-11 42.7 6.6 1.4 1 0 0 1 1 1 1 RING-variant domain FANCL_C PF11793.8 PSC75339.1 - 0.014 15.5 2.1 0.03 14.5 2.2 1.5 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_2 PF13639.6 PSC75339.1 - 0.028 14.7 4.3 0.049 14.0 4.3 1.4 1 0 0 1 1 1 0 Ring finger domain DNA_methylase PF00145.17 PSC75340.1 - 3e-32 112.3 0.0 7e-31 107.8 0.0 2.3 2 0 0 2 2 2 1 C-5 cytosine-specific DNA methylase LBR_tudor PF09465.10 PSC75340.1 - 0.0033 17.2 0.3 10 6.0 0.0 3.4 3 0 0 3 3 3 2 Lamin-B receptor of TUDOR domain GATA PF00320.27 PSC75342.1 - 1.5e-07 30.9 17.9 1.8e-06 27.4 4.8 3.0 2 1 0 2 2 2 2 GATA zinc finger DZR PF12773.7 PSC75342.1 - 0.0093 16.0 13.6 0.5 10.4 12.7 2.5 1 1 1 2 2 2 1 Double zinc ribbon CTU2 PF10288.9 PSC75342.1 - 0.033 14.4 5.3 0.046 14.0 0.2 2.2 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 zinc-ribbon_6 PF10005.9 PSC75342.1 - 0.047 14.4 0.3 0.047 14.4 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Rubredoxin_2 PF18073.1 PSC75342.1 - 0.079 12.7 15.0 0.7 9.7 7.3 2.6 2 0 0 2 2 2 0 Rubredoxin metal binding domain zf-ribbon_3 PF13248.6 PSC75342.1 - 0.085 12.3 13.1 0.21 11.1 2.3 3.3 2 1 0 2 2 2 0 zinc-ribbon domain zf-CHY PF05495.12 PSC75342.1 - 0.52 10.8 10.8 0.46 11.0 3.9 2.4 1 1 1 2 2 2 0 CHY zinc finger C1_2 PF03107.16 PSC75342.1 - 0.71 10.2 10.8 0.76 10.1 1.0 3.2 2 1 0 2 2 2 0 C1 domain zf-RRN7 PF11781.8 PSC75342.1 - 0.96 9.2 8.4 19 5.1 0.5 3.4 3 0 0 3 3 3 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 DUF1924 PF09086.11 PSC75342.1 - 1.5 9.2 6.8 2 8.8 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1924) FYVE_2 PF02318.16 PSC75342.1 - 1.9 8.7 9.9 5.7 7.2 4.2 2.3 1 1 1 2 2 2 0 FYVE-type zinc finger OrfB_Zn_ribbon PF07282.11 PSC75342.1 - 2 8.4 12.4 0.95 9.4 2.7 2.3 2 0 0 2 2 2 0 Putative transposase DNA-binding domain zinc_ribbon_2 PF13240.6 PSC75342.1 - 3.1 7.6 13.4 4.3 7.2 0.5 3.0 3 1 0 3 3 3 0 zinc-ribbon domain Fer4_17 PF13534.6 PSC75342.1 - 3.7 8.2 9.5 0.31 11.6 1.9 2.6 4 0 0 4 4 3 0 4Fe-4S dicluster domain DUF2367 PF10164.9 PSC75342.1 - 3.9 8.0 5.8 15 6.2 0.6 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) Lipase_GDSL_2 PF13472.6 PSC75343.1 - 8.3e-09 36.1 0.0 1.7e-08 35.1 0.0 1.6 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family zf-TFIIB PF13453.6 PSC75344.1 - 0.042 13.2 0.3 0.092 12.1 0.3 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger Fcf1 PF04900.12 PSC75345.1 - 3.1e-39 133.4 4.8 4.2e-39 132.9 4.8 1.2 1 0 0 1 1 1 1 Fcf1 PIN_9 PF18477.1 PSC75345.1 - 2.1e-13 50.6 0.0 3.3e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 PIN like domain Epimerase PF01370.21 PSC75346.1 - 1.4e-35 123.0 0.6 5.1e-20 72.0 0.1 2.8 2 2 1 3 3 3 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 PSC75346.1 - 9.2e-18 64.2 0.0 2.8e-11 43.0 0.0 2.6 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 PSC75346.1 - 6.3e-15 55.5 10.9 2.8e-10 40.4 0.5 2.8 3 0 0 3 3 3 2 NAD(P)H-binding KR PF08659.10 PSC75346.1 - 1.3e-13 51.3 5.9 6.7e-09 35.9 0.7 2.7 2 1 0 2 2 2 2 KR domain GDP_Man_Dehyd PF16363.5 PSC75346.1 - 9e-12 45.0 0.0 1.3e-05 24.7 0.0 2.5 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 PSC75346.1 - 2.3e-09 36.8 0.2 0.00012 21.3 0.0 3.9 3 1 0 3 3 3 2 Male sterility protein adh_short PF00106.25 PSC75346.1 - 1.3e-07 31.3 7.1 0.0005 19.6 0.5 3.5 4 0 0 4 4 4 2 short chain dehydrogenase Polysacc_synt_2 PF02719.15 PSC75346.1 - 4.1e-07 29.4 0.0 0.0047 16.1 0.0 2.4 2 1 0 2 2 2 2 Polysaccharide biosynthesis protein 2-Hacid_dh_C PF02826.19 PSC75346.1 - 7.2e-06 25.5 0.1 0.14 11.5 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NmrA PF05368.13 PSC75346.1 - 2.7e-05 23.9 0.4 0.06 12.9 0.1 2.4 2 0 0 2 2 2 2 NmrA-like family RmlD_sub_bind PF04321.17 PSC75346.1 - 0.00096 18.3 0.9 1 8.4 0.2 2.6 3 0 0 3 3 3 2 RmlD substrate binding domain DUF2795 PF11387.8 PSC75346.1 - 0.1 12.8 0.7 15 5.9 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2795) ApbA PF02558.16 PSC75346.1 - 4 7.1 5.4 15 5.2 0.4 2.5 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA EF_TS PF00889.19 PSC75347.1 - 4.9e-56 189.6 0.0 6.6e-56 189.2 0.0 1.2 1 0 0 1 1 1 1 Elongation factor TS Rad51 PF08423.11 PSC75347.1 - 0.017 14.4 0.0 0.03 13.6 0.0 1.3 1 0 0 1 1 1 0 Rad51 UBA_4 PF14555.6 PSC75347.1 - 0.12 12.3 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 UBA-like domain Helicase_C PF00271.31 PSC75348.1 - 3.4e-11 43.5 0.0 5.5e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C PF00271.31 PSC75349.1 - 3.4e-11 43.5 0.0 5.5e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ArfGap PF01412.18 PSC75350.1 - 4.9e-42 142.7 0.0 6.7e-42 142.3 0.0 1.2 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf BPL_LplA_LipB PF03099.19 PSC75351.1 - 6.4e-08 32.6 0.0 1e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family TPR_2 PF07719.17 PSC75352.1 - 1.6e-06 27.8 1.6 0.027 14.6 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 PSC75352.1 - 0.011 16.3 5.2 0.011 16.3 5.2 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 PSC75352.1 - 0.023 15.5 9.5 3.1 8.9 1.7 4.3 1 1 3 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 PSC75352.1 - 0.027 14.3 2.1 0.61 10.0 0.1 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat 2Fe-2S_thioredx PF01257.19 PSC75352.1 - 0.047 13.5 3.9 0.089 12.7 2.3 2.2 2 1 0 2 2 2 0 Thioredoxin-like [2Fe-2S] ferredoxin DprA_WH PF17782.1 PSC75352.1 - 0.068 13.3 1.8 0.08 13.1 0.7 1.7 2 0 0 2 2 2 0 DprA winged helix domain TPR_9 PF13371.6 PSC75352.1 - 0.62 10.3 7.1 0.91 9.7 3.1 2.9 1 1 0 2 2 2 0 Tetratricopeptide repeat GTP_cyclohydro2 PF00925.20 PSC75354.1 - 1.3e-55 187.4 0.0 1.9e-55 186.9 0.0 1.2 1 0 0 1 1 1 1 GTP cyclohydrolase II CBM_20 PF00686.19 PSC75355.1 - 4e-16 58.7 0.0 6.3e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Starch binding domain PhzC-PhzF PF02567.16 PSC75356.1 - 2.3e-54 184.8 0.0 2.8e-54 184.5 0.0 1.1 1 0 0 1 1 1 1 Phenazine biosynthesis-like protein AdoHcyase PF05221.17 PSC75356.1 - 0.23 10.5 0.0 0.38 9.8 0.0 1.2 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase KH_1 PF00013.29 PSC75357.1 - 0.0017 18.1 0.0 0.0049 16.7 0.0 1.8 1 0 0 1 1 1 1 KH domain Methyltransf_2 PF00891.18 PSC75358.1 - 2.2e-29 102.3 0.0 3.9e-29 101.5 0.0 1.4 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 PSC75358.1 - 9.2e-07 28.8 0.1 1.9e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Dimerisation domain MarR_2 PF12802.7 PSC75358.1 - 0.014 15.2 0.7 0.042 13.7 0.7 1.8 1 0 0 1 1 1 0 MarR family Methyltransf_23 PF13489.6 PSC75358.1 - 0.026 14.3 0.0 0.078 12.8 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 PSC75358.1 - 0.09 13.5 0.0 0.2 12.4 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TetR_C_16 PF17920.1 PSC75358.1 - 0.22 11.8 4.3 1.2 9.3 0.0 3.3 4 0 0 4 4 4 0 Tetracyclin repressor-like, C-terminal domain AAA PF00004.29 PSC75359.1 - 2.5e-36 125.0 0.0 4.8e-36 124.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PSC75359.1 - 9.6e-11 41.3 0.0 5.2e-10 39.0 0.0 2.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 PSC75359.1 - 3.4e-06 27.1 0.0 9.2e-06 25.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PSC75359.1 - 0.00086 19.6 0.2 0.2 11.9 0.0 2.6 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 PSC75359.1 - 0.0037 17.0 0.0 0.0074 16.1 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 PSC75359.1 - 0.0094 16.1 0.7 0.059 13.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain Vps4_C PF09336.10 PSC75359.1 - 0.037 14.0 0.0 0.075 13.0 0.0 1.5 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_25 PF13481.6 PSC75359.1 - 0.048 13.2 2.2 1.2 8.6 0.1 3.8 4 0 0 4 4 4 0 AAA domain AAA_18 PF13238.6 PSC75359.1 - 0.051 14.1 0.0 0.13 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 PSC75359.1 - 0.06 12.5 0.2 0.22 10.7 0.1 1.8 1 1 1 2 2 2 0 TIP49 P-loop domain IstB_IS21 PF01695.17 PSC75359.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 PSC75359.1 - 0.13 11.6 0.6 0.28 10.5 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI M PF02370.16 PSC75359.1 - 0.14 12.8 4.9 0.87 10.4 4.9 2.4 1 0 0 1 1 1 0 M protein repeat AAA_16 PF13191.6 PSC75359.1 - 7.9 6.8 19.5 2 8.8 10.0 4.3 3 1 0 3 3 3 0 AAA ATPase domain SBP_bac_3 PF00497.20 PSC75360.1 - 1.8e-19 70.1 0.0 2.8e-19 69.5 0.0 1.3 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 PSC75360.1 - 8.5e-16 58.1 0.2 1.6e-15 57.2 0.2 1.5 1 0 0 1 1 1 1 Ligand-gated ion channel BatD PF13584.6 PSC75360.1 - 0.0069 15.2 0.6 0.47 9.2 0.0 2.2 2 0 0 2 2 2 2 Oxygen tolerance stn_TNFRSF12A PF12191.8 PSC75360.1 - 0.0074 16.5 0.1 0.031 14.5 0.1 2.1 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Herpes_gE PF02480.16 PSC75360.1 - 0.16 10.7 0.1 0.31 9.8 0.1 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E DUF2207 PF09972.9 PSC75360.1 - 0.16 10.7 2.8 0.88 8.3 0.0 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) CoA_binding_3 PF13727.6 PSC75360.1 - 1.1 9.2 5.6 0.48 10.4 0.8 2.3 2 0 0 2 2 2 0 CoA-binding domain TBP PF00352.21 PSC75361.1 - 5.8e-69 228.1 0.2 3.2e-33 113.5 0.0 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 PSC75361.1 - 1.4e-05 25.2 0.0 0.059 13.5 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) FbpA PF05833.11 PSC75362.1 - 1.8e-36 125.9 0.0 1.1e-34 120.1 0.0 2.5 2 1 0 2 2 2 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 PSC75362.1 - 3.7e-31 108.0 0.0 9.8e-31 106.6 0.0 1.8 1 0 0 1 1 1 1 NFACT protein RNA binding domain NFACT-C PF11923.8 PSC75362.1 - 1.4e-26 92.4 0.0 1.4e-26 92.4 0.0 2.6 3 0 0 3 3 3 1 NFACT protein C-terminal domain Methyltransf_11 PF08241.12 PSC75365.1 - 2.5e-15 56.9 0.1 8.5e-15 55.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC75365.1 - 8.8e-10 38.3 0.0 1.3e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 PSC75365.1 - 1.3e-09 38.7 0.0 4e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC75365.1 - 2e-07 31.0 0.0 2.9e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC75365.1 - 3.4e-07 30.2 0.0 4.5e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC75365.1 - 0.00016 22.4 0.0 0.00031 21.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 PSC75365.1 - 0.00027 20.9 0.0 0.0004 20.3 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_24 PF13578.6 PSC75365.1 - 0.038 15.0 0.2 0.28 12.2 0.0 2.5 2 1 1 3 3 3 0 Methyltransferase domain Peptidase_C1 PF00112.23 PSC75366.1 - 2.7e-50 171.5 5.7 3.7e-50 171.0 5.7 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 PSC75366.1 - 0.062 12.1 1.1 0.065 12.0 0.1 1.4 2 0 0 2 2 2 0 Peptidase C1-like family Bac_globin PF01152.21 PSC75367.1 - 2.8e-14 53.3 0.0 4.3e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Bacterial-like globin CBS PF00571.28 PSC75368.1 - 2.9e-22 78.8 0.2 3.7e-10 40.1 0.0 4.6 5 0 0 5 5 5 4 CBS domain IMS_HHH PF11798.8 PSC75368.1 - 0.01 16.1 0.0 0.026 14.9 0.0 1.6 1 0 0 1 1 1 0 IMS family HHH motif HlyIII PF03006.20 PSC75369.1 - 5.1e-58 196.4 21.9 2.9e-57 194.0 21.9 1.9 1 1 0 1 1 1 1 Haemolysin-III related DUF962 PF06127.11 PSC75369.1 - 0.27 11.4 3.1 4.4 7.5 3.1 3.0 1 1 0 1 1 1 0 Protein of unknown function (DUF962) AF-4 PF05110.13 PSC75369.1 - 0.87 7.6 4.0 1.1 7.2 4.0 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Peptidase_C13 PF01650.18 PSC75370.1 - 1.1e-31 110.3 0.0 1.5e-31 109.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family Peptidase_C13 PF01650.18 PSC75371.1 - 9.2e-32 110.5 0.0 1.2e-31 110.1 0.0 1.1 1 0 0 1 1 1 1 Peptidase C13 family K-cyclin_vir_C PF09080.10 PSC75372.1 - 3.5 8.1 6.5 2 8.9 1.0 2.1 2 0 0 2 2 2 0 K cyclin, C terminal WD40 PF00400.32 PSC75373.1 - 1.5e-51 171.2 21.4 3.5e-09 37.1 0.2 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC75373.1 - 1.4e-34 118.3 1.4 7e-09 35.9 0.0 6.4 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 PSC75373.1 - 1.5e-08 34.8 0.0 0.0019 18.1 0.0 3.8 2 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 PSC75373.1 - 5.5e-08 32.5 0.1 1.2e-07 31.4 0.1 1.6 1 0 0 1 1 1 1 LisH Ge1_WD40 PF16529.5 PSC75373.1 - 0.0002 20.4 1.7 4.6 6.1 0.0 4.5 2 2 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 PSC75373.1 - 0.00052 20.0 0.0 1.5 8.9 0.0 3.1 2 1 0 2 2 2 2 Ciliary BBSome complex subunit 2, middle region IKI3 PF04762.12 PSC75373.1 - 0.00085 17.4 1.0 0.79 7.6 0.0 3.7 4 0 0 4 4 4 1 IKI3 family Nucleoporin_N PF08801.11 PSC75373.1 - 0.012 14.4 0.0 3.3 6.3 0.0 3.1 2 1 1 3 3 3 0 Nup133 N terminal like Nup160 PF11715.8 PSC75373.1 - 0.018 13.7 0.0 2.6 6.6 0.0 2.4 2 1 0 2 2 2 0 Nucleoporin Nup120/160 RAB3GAP2_N PF14655.6 PSC75373.1 - 0.036 13.4 0.0 0.11 11.7 0.0 1.8 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Prefoldin PF02996.17 PSC75373.1 - 0.088 12.7 0.1 0.14 12.0 0.1 1.2 1 0 0 1 1 1 0 Prefoldin subunit PALB2_WD40 PF16756.5 PSC75373.1 - 0.12 11.2 3.9 0.31 9.9 0.3 2.6 2 1 0 2 2 2 0 Partner and localizer of BRCA2 WD40 domain WD40_like PF17005.5 PSC75373.1 - 0.17 11.2 0.0 0.45 9.8 0.0 1.7 2 0 0 2 2 2 0 WD40-like domain DUF4972 PF16342.5 PSC75373.1 - 0.17 11.6 0.1 0.52 10.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4972) CHAP PF05257.16 PSC75373.1 - 0.57 10.8 3.7 12 6.6 2.8 3.3 2 1 0 2 2 2 0 CHAP domain Sulfotransfer_2 PF03567.14 PSC75375.1 - 4.6e-08 33.3 0.0 7.5e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family PC-Esterase PF13839.6 PSC75375.1 - 4.8e-06 26.5 3.8 0.0084 15.9 0.0 3.9 3 2 0 3 3 3 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p CAP_N PF01213.19 PSC75375.1 - 6.8 6.1 9.3 0.54 9.7 2.7 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Peptidase_S10 PF00450.22 PSC75376.1 - 4.7e-99 332.6 0.0 5.8e-99 332.3 0.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase Aldo_ket_red PF00248.21 PSC75376.1 - 8.3e-57 192.6 0.0 1.1e-56 192.2 0.0 1.2 1 0 0 1 1 1 1 Aldo/keto reductase family SRP54 PF00448.22 PSC75377.1 - 5.4e-56 189.3 0.1 3.2e-55 186.8 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 PSC75377.1 - 2.1e-50 172.3 0.0 3.4e-50 171.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle, alpha subunit, N-terminal GTP_EFTU PF00009.27 PSC75377.1 - 5.4e-45 153.3 0.0 1.9e-44 151.6 0.1 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 PSC75377.1 - 5.7e-12 45.8 1.3 3.8e-11 43.2 0.6 2.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 PSC75377.1 - 1.4e-11 44.7 0.1 7.1e-11 42.4 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 PSC75377.1 - 7.6e-08 32.4 1.2 0.012 15.7 0.0 4.6 4 1 0 4 4 4 2 50S ribosome-binding GTPase MeaB PF03308.16 PSC75377.1 - 4e-06 26.0 0.4 6.5e-05 22.0 0.0 2.9 3 0 0 3 3 3 1 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_22 PF13401.6 PSC75377.1 - 1.7e-05 25.1 0.0 0.0085 16.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 PSC75377.1 - 0.00024 21.1 0.1 0.52 10.2 0.0 2.9 2 1 0 2 2 2 2 RsgA GTPase SRP54_N PF02881.19 PSC75377.1 - 0.0012 19.1 1.5 0.0018 18.4 0.2 2.1 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain AAA_30 PF13604.6 PSC75377.1 - 0.0013 18.4 0.0 0.0036 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 PSC75377.1 - 0.003 17.3 0.0 0.018 14.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PSC75377.1 - 0.003 17.9 0.5 0.012 16.0 0.0 2.3 2 0 0 2 2 1 1 AAA ATPase domain GTP_EFTU_D4 PF14578.6 PSC75377.1 - 0.011 15.6 0.7 0.035 14.0 0.7 1.9 1 0 0 1 1 1 0 Elongation factor Tu domain 4 CbiA PF01656.23 PSC75377.1 - 0.012 15.6 1.9 0.11 12.5 0.4 3.0 2 1 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain NTPase_1 PF03266.15 PSC75377.1 - 0.021 14.7 0.5 1.9 8.4 0.1 2.9 3 0 0 3 3 3 0 NTPase AAA_31 PF13614.6 PSC75377.1 - 0.028 14.3 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain Fer4_NifH PF00142.18 PSC75377.1 - 0.029 13.8 0.1 0.029 13.8 0.1 2.3 3 0 0 3 3 2 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family KTI12 PF08433.10 PSC75377.1 - 0.036 13.5 0.0 0.62 9.5 0.0 2.2 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_33 PF13671.6 PSC75377.1 - 0.037 14.2 0.0 2.6 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 PSC75377.1 - 0.046 13.5 0.2 11 5.8 0.0 3.3 3 0 0 3 3 2 0 P-loop containing region of AAA domain CLP1_P PF16575.5 PSC75377.1 - 0.055 13.3 0.0 2.2 8.1 0.0 2.9 3 0 0 3 3 3 0 mRNA cleavage and polyadenylation factor CLP1 P-loop ParA PF10609.9 PSC75377.1 - 0.077 12.4 0.1 0.31 10.4 0.0 2.0 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase G-alpha PF00503.20 PSC75377.1 - 0.097 11.8 0.1 11 5.1 0.1 2.7 3 0 0 3 3 3 0 G-protein alpha subunit AIG1 PF04548.16 PSC75377.1 - 0.11 11.8 0.4 8.3 5.7 0.1 3.2 3 1 0 3 3 3 0 AIG1 family ArsA_ATPase PF02374.15 PSC75377.1 - 0.15 11.2 0.1 0.29 10.3 0.1 1.4 1 0 0 1 1 1 0 Anion-transporting ATPase Dpoe2NT PF12213.8 PSC75377.1 - 0.21 11.9 0.5 0.48 10.7 0.5 1.6 1 0 0 1 1 1 0 DNA polymerases epsilon N terminal Ras PF00071.22 PSC75377.1 - 0.88 9.1 4.6 3.2 7.3 0.1 3.5 3 1 0 3 3 3 0 Ras family Synaptobrevin PF00957.21 PSC75378.1 - 1.3e-32 111.4 4.7 1.9e-32 110.9 4.7 1.2 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 PSC75378.1 - 1.7e-17 63.2 0.0 3e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Abhydrolase_1 PF00561.20 PSC75378.1 - 5.6e-05 22.9 0.1 0.014 15.1 0.2 2.8 2 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC75378.1 - 0.019 14.2 0.5 6 6.1 0.1 2.8 3 0 0 3 3 3 0 Serine aminopeptidase, S33 ATP-synt_ab PF00006.25 PSC75379.1 - 2.4e-63 213.6 0.0 3.6e-63 213.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 PSC75379.1 - 1.1e-20 73.9 0.5 2.8e-20 72.6 0.5 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain AAA_16 PF13191.6 PSC75379.1 - 0.045 14.1 0.0 0.11 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 PSC75379.1 - 0.048 12.8 1.5 0.051 12.7 0.2 1.6 2 0 0 2 2 2 0 NB-ARC domain NACHT PF05729.12 PSC75379.1 - 0.063 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ATPase_2 PF01637.18 PSC75379.1 - 0.07 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea RnfC_N PF13375.6 PSC75379.1 - 0.092 12.7 0.2 0.29 11.1 0.1 1.8 1 1 0 1 1 1 0 RnfC Barrel sandwich hybrid domain RsgA_GTPase PF03193.16 PSC75379.1 - 0.14 12.0 0.1 0.33 10.8 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA PF00004.29 PSC75379.1 - 0.17 12.3 0.1 1.7 9.0 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Barwin PF00967.17 PSC75380.1 - 0.0023 17.8 0.2 0.0023 17.8 0.2 2.0 2 0 0 2 2 2 1 Barwin family DPBB_1 PF03330.18 PSC75380.1 - 0.023 14.9 0.3 0.088 13.1 0.0 2.2 2 0 0 2 2 2 0 Lytic transglycolase CBM_20 PF00686.19 PSC75382.1 - 4.1e-06 26.6 0.2 4.1e-06 26.6 0.2 3.0 2 1 1 3 3 3 2 Starch binding domain Presenilin PF01080.17 PSC75382.1 - 0.00013 20.9 13.7 0.00013 20.9 13.7 3.0 2 1 0 2 2 2 1 Presenilin EPL1 PF10513.9 PSC75382.1 - 0.0006 20.2 7.5 0.0006 20.2 7.5 3.0 2 1 0 2 2 2 1 Enhancer of polycomb-like Exonuc_VII_L PF02601.15 PSC75382.1 - 0.0023 17.5 18.9 0.0023 17.5 18.9 2.6 2 1 0 2 2 2 1 Exonuclease VII, large subunit SET PF00856.28 PSC75382.1 - 0.0047 17.3 0.0 0.0047 17.3 0.0 4.7 2 1 0 2 2 2 1 SET domain ABC2_membrane_2 PF12679.7 PSC75382.1 - 1.6 7.9 3.7 4.6 6.4 3.7 1.8 1 0 0 1 1 1 0 ABC-2 family transporter protein Zip PF02535.22 PSC75382.1 - 7.1 5.7 14.2 0.42 9.8 3.4 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Bax1-I PF01027.20 PSC75383.1 - 1.1e-36 126.6 28.4 1.4e-36 126.3 28.4 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Pox_A14 PF05767.12 PSC75383.1 - 0.028 14.6 0.8 0.028 14.6 0.8 3.1 2 1 2 4 4 4 0 Poxvirus virion envelope protein A14 zf-CCCH PF00642.24 PSC75384.1 - 1e-07 31.7 1.5 1e-07 31.7 1.5 3.2 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Ank_4 PF13637.6 PSC75384.1 - 1.3e-07 32.0 0.2 3.8e-07 30.5 0.2 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 PSC75384.1 - 1.5e-07 31.5 3.1 2.1e-05 24.7 0.2 3.0 2 0 0 2 2 2 2 Ankyrin repeat zf_CCCH_4 PF18345.1 PSC75384.1 - 5.1e-06 26.3 2.5 5.1e-06 26.3 2.5 3.3 4 0 0 4 4 4 1 Zinc finger domain Ank_2 PF12796.7 PSC75384.1 - 4.6e-05 23.9 0.3 0.00018 22.1 0.3 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) zf-CCCH_4 PF18044.1 PSC75384.1 - 0.00016 21.4 2.2 0.00016 21.4 2.2 2.9 3 0 0 3 3 3 1 CCCH-type zinc finger Ank_3 PF13606.6 PSC75384.1 - 0.00055 20.2 0.6 0.036 14.6 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 PSC75384.1 - 0.011 16.0 5.9 0.014 15.7 0.1 3.3 2 1 1 3 3 3 0 Ankyrin repeats (many copies) zf-CCCH_2 PF14608.6 PSC75384.1 - 0.15 12.5 0.2 0.15 12.5 0.2 3.9 4 0 0 4 4 4 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 PSC75384.1 - 0.99 10.1 5.7 0.17 12.6 1.8 1.7 2 0 0 2 2 2 0 Torus domain Phage_DNA_bind PF02303.17 PSC75385.1 - 0.16 12.2 0.0 0.45 10.8 0.0 1.7 1 0 0 1 1 1 0 Helix-destabilising protein Suf PF05843.14 PSC75386.1 - 0.0024 17.9 12.8 0.0034 17.4 12.8 1.3 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Utp21 PF04192.12 PSC75386.1 - 0.0025 17.4 3.9 0.0035 16.9 3.9 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain Merozoite_SPAM PF07133.11 PSC75386.1 - 0.016 15.2 7.8 0.025 14.6 7.8 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.14 PSC75386.1 - 0.016 13.5 8.4 0.019 13.3 8.4 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF-3_zeta PF05091.12 PSC75386.1 - 0.019 14.0 8.5 0.02 13.9 8.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DDHD PF02862.17 PSC75386.1 - 0.027 14.6 4.0 0.031 14.4 4.0 1.3 1 0 0 1 1 1 0 DDHD domain TFIIA PF03153.13 PSC75386.1 - 0.039 14.0 33.6 0.051 13.6 33.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NPR3 PF03666.13 PSC75386.1 - 0.056 12.2 6.6 0.064 12.0 6.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Neur_chan_memb PF02932.16 PSC75386.1 - 0.066 13.3 4.5 0.072 13.1 4.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 PSC75386.1 - 0.066 12.0 11.5 0.075 11.8 11.5 1.2 1 0 0 1 1 1 0 Presenilin Tim54 PF11711.8 PSC75386.1 - 0.074 11.8 7.3 0.1 11.4 7.3 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TRAP_alpha PF03896.16 PSC75386.1 - 0.085 12.1 8.6 0.17 11.1 7.2 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Zip PF02535.22 PSC75386.1 - 0.092 11.9 1.9 0.11 11.7 1.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF3292 PF11696.8 PSC75386.1 - 0.12 10.7 6.4 0.17 10.2 6.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) Band_3_cyto PF07565.13 PSC75386.1 - 0.12 12.1 4.8 0.16 11.7 4.8 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_S49_N PF08496.10 PSC75386.1 - 0.16 12.0 5.5 0.23 11.5 5.5 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SLC12 PF03522.15 PSC75386.1 - 0.19 10.7 7.3 0.2 10.6 7.3 1.1 1 0 0 1 1 1 0 Solute carrier family 12 RPN2_C PF18004.1 PSC75386.1 - 0.21 11.5 11.2 0.31 10.9 11.2 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Hamartin PF04388.12 PSC75386.1 - 0.35 9.5 7.3 0.4 9.3 7.3 1.1 1 0 0 1 1 1 0 Hamartin protein SpoIIP PF07454.11 PSC75386.1 - 0.36 10.3 10.3 0.48 9.8 10.3 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) SAPS PF04499.15 PSC75386.1 - 0.48 9.2 7.3 0.53 9.0 7.3 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein PAT1 PF09770.9 PSC75386.1 - 0.66 8.2 20.1 0.73 8.0 20.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Raftlin PF15250.6 PSC75386.1 - 0.9 8.2 9.6 1.1 8.0 9.6 1.1 1 0 0 1 1 1 0 Raftlin Ndc1_Nup PF09531.10 PSC75386.1 - 1 8.0 9.4 1.1 7.8 9.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Gti1_Pac2 PF09729.9 PSC75386.1 - 1.1 9.4 6.6 1.6 8.8 6.6 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family XAP5 PF04921.14 PSC75386.1 - 1.1 9.1 10.5 1.6 8.5 10.5 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator CLN3 PF02487.17 PSC75386.1 - 1.2 8.1 4.7 1.4 7.8 4.7 1.1 1 0 0 1 1 1 0 CLN3 protein FAM60A PF15396.6 PSC75386.1 - 1.2 9.0 6.6 1.8 8.5 6.6 1.2 1 0 0 1 1 1 0 Protein Family FAM60A PPP4R2 PF09184.11 PSC75386.1 - 1.4 8.4 9.1 1.9 8.0 9.1 1.2 1 0 0 1 1 1 0 PPP4R2 EOS1 PF12326.8 PSC75386.1 - 1.7 8.6 2.8 2.2 8.2 2.8 1.2 1 0 0 1 1 1 0 N-glycosylation protein Connexin PF00029.19 PSC75386.1 - 1.7 8.3 7.6 2.5 7.8 7.6 1.2 1 0 0 1 1 1 0 Connexin EIIBC-GUT_N PF03612.14 PSC75386.1 - 1.9 8.2 10.3 3.1 7.5 10.3 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Peptidase_S64 PF08192.11 PSC75386.1 - 1.9 6.9 8.2 2.2 6.7 8.2 1.1 1 0 0 1 1 1 0 Peptidase family S64 Sec62 PF03839.16 PSC75386.1 - 2.1 7.8 6.4 2.8 7.4 6.4 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 GREB1 PF15782.5 PSC75386.1 - 2.1 5.3 9.8 2.7 5.0 9.8 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Folate_carrier PF01770.18 PSC75386.1 - 2.7 6.6 4.3 3.6 6.2 4.3 1.1 1 0 0 1 1 1 0 Reduced folate carrier TERB2 PF15101.6 PSC75386.1 - 3.2 7.8 13.6 4.8 7.2 13.6 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 MDM10 PF12519.8 PSC75386.1 - 4.1 6.2 7.5 4.8 5.9 7.5 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 OATP PF03137.20 PSC75386.1 - 4.1 5.6 4.3 5.4 5.2 4.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF5308 PF17233.2 PSC75386.1 - 4.2 7.6 18.0 11 6.1 17.3 2.1 1 1 0 1 1 1 0 Family of unknown function (DUF5308) AIF_C PF14721.6 PSC75386.1 - 4.6 7.6 9.0 9.5 6.6 9.0 1.6 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Orf78 PF06024.12 PSC75386.1 - 5.6 7.3 8.5 12 6.3 8.5 1.5 1 0 0 1 1 1 0 Orf78 (ac78) UPF0560 PF10577.9 PSC75386.1 - 6.5 5.1 15.4 7.7 4.9 15.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 GET2 PF08690.10 PSC75386.1 - 6.5 6.3 13.2 11 5.6 13.2 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 DUF1980 PF09323.10 PSC75386.1 - 6.9 6.5 8.2 11 5.9 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Serinc PF03348.15 PSC75386.1 - 8.1 5.3 5.7 10 4.9 5.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Sld5 PF05916.11 PSC75387.1 - 1.7e-05 25.2 0.0 2.8e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 GINS complex protein TPR_1 PF00515.28 PSC75387.1 - 0.00027 20.6 1.0 0.027 14.3 0.6 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 PSC75387.1 - 0.0053 17.0 0.4 0.0053 17.0 0.4 2.8 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_2 PF07719.17 PSC75387.1 - 0.0062 16.6 1.9 0.0062 16.6 1.9 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 PSC75387.1 - 0.029 14.4 0.4 0.3 11.2 0.1 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 PSC75387.1 - 0.059 14.0 4.8 2.7 8.8 0.0 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-PARP PF00645.18 PSC75388.1 - 2e-18 67.0 0.1 2e-18 67.0 0.1 1.9 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region F-box-like PF12937.7 PSC75388.1 - 2.1e-06 27.5 1.3 5.1e-06 26.3 1.3 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PSC75388.1 - 1.9e-05 24.4 0.4 5.9e-05 22.8 0.4 1.8 1 0 0 1 1 1 1 F-box domain CDC27 PF09507.10 PSC75388.1 - 2.1 7.7 31.2 3.1 7.1 31.2 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 HAP2-GCS1 PF10699.9 PSC75389.1 - 9.1e-14 51.2 0.6 2.6e-13 49.7 0.0 2.2 2 0 0 2 2 2 1 Male gamete fusion factor DUF4464 PF14713.6 PSC75391.1 - 5e-80 268.3 0.0 5.9e-80 268.0 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4464) adh_short PF00106.25 PSC75392.1 - 3.4e-13 49.5 0.0 1.5e-12 47.4 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC75392.1 - 8.6e-10 38.6 0.1 1.5e-08 34.5 0.1 2.1 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase CENP-F_leu_zip PF10473.9 PSC75393.1 - 0.026 14.6 20.4 0.47 10.5 10.0 3.1 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 ATG16 PF08614.11 PSC75393.1 - 0.52 10.5 41.7 1.5 9.0 21.0 2.1 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Cep57_MT_bd PF06657.13 PSC75393.1 - 0.61 10.6 9.9 4.2 7.9 5.6 3.2 2 1 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 APG6_N PF17675.1 PSC75393.1 - 0.73 10.4 35.2 15 6.1 10.8 2.6 1 1 1 2 2 2 0 Apg6 coiled-coil region ERM PF00769.19 PSC75393.1 - 0.85 9.4 54.8 0.88 9.3 25.4 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF724 PF05266.14 PSC75393.1 - 0.85 9.4 24.4 1.3 8.8 4.5 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF724) TFIIA PF03153.13 PSC75393.1 - 1.9 8.4 22.3 2.3 8.1 22.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CLP_protease PF00574.23 PSC75394.1 - 6.1e-55 185.9 0.0 8e-55 185.5 0.0 1.1 1 0 0 1 1 1 1 Clp protease Man-6-P_recep PF02157.15 PSC75394.1 - 0.046 12.8 0.0 0.058 12.5 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate receptor Fe_dep_repr_C PF02742.15 PSC75394.1 - 0.048 13.7 0.0 0.14 12.3 0.0 1.8 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain MAPEG PF01124.18 PSC75395.1 - 7.8e-18 64.6 4.4 7.8e-18 64.6 4.4 2.6 2 0 0 2 2 2 1 MAPEG family DUF2358 PF10184.9 PSC75395.1 - 1.5e-15 57.4 0.0 8.1e-08 32.5 0.0 2.4 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2358) PAP2_C PF14360.6 PSC75395.1 - 2.8e-11 43.8 0.1 7.5e-11 42.4 0.1 1.8 1 0 0 1 1 1 1 PAP2 superfamily C-terminal GTP1_OBG PF01018.22 PSC75395.1 - 0.35 10.4 6.3 0.36 10.4 2.6 2.1 2 0 0 2 2 2 0 GTP1/OBG SNF2_N PF00176.23 PSC75396.1 - 1.4e-24 86.5 0.0 2.4e-24 85.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC75396.1 - 9.1e-09 35.6 0.0 1.7e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain HNH PF01844.23 PSC75396.1 - 7e-06 26.1 0.0 1.8e-05 24.8 0.0 1.7 1 0 0 1 1 1 1 HNH endonuclease ResIII PF04851.15 PSC75396.1 - 0.00082 19.4 0.0 0.0017 18.4 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Chlorophyllase2 PF12740.7 PSC75396.1 - 0.011 14.7 0.0 0.022 13.7 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 PSC75396.1 - 0.012 14.7 0.0 0.021 13.9 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase HNH_5 PF14279.6 PSC75396.1 - 0.013 15.4 0.3 0.038 13.9 0.0 1.9 2 0 0 2 2 2 0 HNH endonuclease Lipase_3 PF01764.25 PSC75396.1 - 0.11 12.3 0.1 0.24 11.3 0.1 1.4 1 0 0 1 1 1 0 Lipase (class 3) TFIIA PF03153.13 PSC75396.1 - 5 7.0 15.5 0.18 11.8 9.2 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RRM_1 PF00076.22 PSC75397.1 - 5.3e-54 179.9 0.0 5.2e-17 61.4 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PSC75397.1 - 1.6e-06 27.7 0.0 0.0026 17.4 0.0 2.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PSC75397.1 - 1.8e-05 24.6 0.2 0.00075 19.5 0.0 2.7 2 1 0 2 2 2 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 PSC75397.1 - 0.0034 17.5 0.0 9 6.5 0.0 3.4 3 1 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 PSC75397.1 - 0.015 15.2 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF4523 PF15023.6 PSC75397.1 - 0.023 14.5 0.0 0.1 12.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) RRM_3 PF08777.11 PSC75397.1 - 0.078 13.0 0.0 0.86 9.7 0.0 2.2 2 0 0 2 2 2 0 RNA binding motif Kri1_C PF12936.7 PSC75398.1 - 2.6e-27 94.8 0.5 2.6e-27 94.8 0.5 2.9 2 0 0 2 2 2 1 KRI1-like family C-terminal Kri1 PF05178.12 PSC75398.1 - 1.5e-16 60.8 17.6 1.5e-16 60.8 17.6 5.4 5 3 0 5 5 5 1 KRI1-like family PsaD PF02531.16 PSC75399.1 - 3.3e-67 224.2 0.0 4.1e-67 223.9 0.0 1.1 1 0 0 1 1 1 1 PsaD PEMT PF04191.13 PSC75400.1 - 3.7e-10 40.2 0.0 5.5e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Phospholipid methyltransferase CUE PF02845.16 PSC75400.1 - 2.2e-06 27.2 0.0 4.3e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 CUE domain ERG4_ERG24 PF01222.17 PSC75400.1 - 2.1e-05 23.5 0.0 2.8e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family ICMT PF04140.14 PSC75400.1 - 0.0066 16.8 0.0 0.011 16.1 0.0 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family Steroid_dh PF02544.16 PSC75400.1 - 0.009 16.0 0.0 0.013 15.4 0.0 1.2 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase Med3 PF11593.8 PSC75400.1 - 0.041 13.1 9.8 0.065 12.4 9.8 1.4 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NnrU PF07298.11 PSC75400.1 - 0.042 13.4 0.1 0.1 12.1 0.1 1.7 1 0 0 1 1 1 0 NnrU protein DUF2353 PF09789.9 PSC75400.1 - 1.6 8.0 5.8 2.4 7.4 5.8 1.2 1 0 0 1 1 1 0 Uncharacterized coiled-coil protein (DUF2353) Spt20 PF12090.8 PSC75400.1 - 7.2 6.1 14.4 14 5.2 14.4 1.4 1 0 0 1 1 1 0 Spt20 family Glutaredoxin PF00462.24 PSC75401.1 - 1.3e-16 60.6 0.0 1.8e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 PSC75401.1 - 0.00014 21.8 0.0 0.00021 21.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain DSBA PF01323.20 PSC75401.1 - 0.00043 20.1 1.4 0.045 13.5 0.3 2.1 1 1 1 2 2 2 2 DSBA-like thioredoxin domain DUF836 PF05768.14 PSC75401.1 - 0.032 14.6 0.2 0.044 14.2 0.2 1.4 1 1 0 1 1 1 0 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.6 PSC75401.1 - 0.048 13.8 0.6 5.1 7.2 0.8 2.1 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.6 PSC75401.1 - 0.077 13.5 0.7 0.1 13.1 0.7 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain Hydrolase_4 PF12146.8 PSC75402.1 - 3e-43 147.8 0.1 4.3e-42 144.0 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PSC75402.1 - 2.2e-08 35.0 2.0 2.2e-08 35.0 2.0 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 PSC75402.1 - 0.00078 19.3 0.2 0.0041 17.0 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PSC75402.1 - 0.024 14.1 0.2 0.33 10.4 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 PSC75402.1 - 0.042 13.5 1.0 0.21 11.2 1.0 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC75403.1 - 3e-43 147.8 0.1 4.3e-42 144.0 0.1 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PSC75403.1 - 2.2e-08 35.0 2.0 2.2e-08 35.0 2.0 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 PSC75403.1 - 0.00078 19.3 0.2 0.0041 17.0 0.2 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 PSC75403.1 - 0.024 14.1 0.2 0.33 10.4 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 PSC75403.1 - 0.042 13.5 1.0 0.21 11.2 1.0 2.2 1 1 0 1 1 1 0 alpha/beta hydrolase fold Complex1_LYR_2 PF13233.6 PSC75404.1 - 1.2e-05 26.0 0.0 1.5e-05 25.7 0.0 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 PSC75404.1 - 0.046 13.8 0.4 0.077 13.0 0.4 1.3 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Glu_cyclase_2 PF05096.12 PSC75405.1 - 1.6e-74 250.5 0.0 2.7e-74 249.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine cyclotransferase p450 PF00067.22 PSC75405.1 - 1.3e-56 192.3 0.0 2.2e-56 191.6 0.0 1.2 1 0 0 1 1 1 1 Cytochrome P450 SGL PF08450.12 PSC75405.1 - 0.043 13.4 0.1 3.7 7.0 0.0 2.5 2 1 0 2 2 2 0 SMP-30/Gluconolactonase/LRE-like region IZUMO PF15005.6 PSC75405.1 - 4.8 7.7 5.7 0.91 10.0 1.1 2.1 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Takusan PF04822.13 PSC75405.1 - 5.5 7.0 8.4 5.4 7.0 2.7 3.1 2 1 0 2 2 2 0 Takusan GCP_N_terminal PF17681.1 PSC75406.1 - 6.3e-32 111.4 0.0 1.8e-31 109.9 0.0 1.8 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 PSC75406.1 - 7.2e-26 91.4 0.0 1.3e-25 90.5 0.0 1.4 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal Polyketide_cyc2 PF10604.9 PSC75406.1 - 0.00011 22.5 0.1 0.00043 20.6 0.1 2.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Ribosomal_L27A PF00828.19 PSC75407.1 - 2.5e-19 70.2 0.0 3.2e-19 69.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Slx4 PF09494.10 PSC75407.1 - 0.17 11.9 0.0 0.34 10.9 0.0 1.4 1 0 0 1 1 1 0 Slx4 endonuclease UBA PF00627.31 PSC75408.1 - 1.4e-06 28.1 3.6 3.1e-06 27.0 0.8 3.0 2 0 0 2 2 2 1 UBA/TS-N domain Myb_DNA-binding PF00249.31 PSC75408.1 - 0.0025 18.0 0.0 0.013 15.7 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain UBA_4 PF14555.6 PSC75408.1 - 0.05 13.4 0.0 0.12 12.2 0.0 1.6 1 0 0 1 1 1 0 UBA-like domain FTA4 PF13093.6 PSC75408.1 - 0.84 9.5 11.7 0.31 10.9 0.5 2.3 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Methyltransf_11 PF08241.12 PSC75409.1 - 4.5e-14 52.9 0.0 7.6e-14 52.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC75409.1 - 6.8e-12 45.9 0.0 1.2e-11 45.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC75409.1 - 1.4e-07 31.4 0.0 2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 PSC75409.1 - 6.3e-07 29.2 0.0 9.4e-07 28.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_23 PF13489.6 PSC75409.1 - 3.3e-06 27.0 0.0 5.2e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC75409.1 - 2.9e-05 24.7 0.0 6.5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 PSC75409.1 - 0.0016 17.8 0.0 0.0023 17.3 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ribosomal_L17 PF01196.19 PSC75410.1 - 1.8e-34 118.5 0.4 2.3e-34 118.1 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L17 Peptidase_M60 PF13402.6 PSC75411.1 - 2.6e-21 76.3 0.1 1.5e-16 60.8 0.1 2.3 2 0 0 2 2 2 2 Peptidase M60, enhancin and enhancin-like M60-like_N PF17291.2 PSC75411.1 - 3.4e-14 52.7 0.0 6.5e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases RNB PF00773.19 PSC75412.1 - 7.2e-63 212.9 0.0 3.8e-61 207.2 0.0 2.1 1 1 0 1 1 1 1 RNB domain Peptidase_C69 PF03577.15 PSC75412.1 - 0.17 10.8 0.0 0.25 10.2 0.0 1.2 1 0 0 1 1 1 0 Peptidase family C69 DUF4080 PF13311.6 PSC75413.1 - 0.13 12.5 1.1 0.17 12.1 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4080) TraG_N PF07916.11 PSC75413.1 - 0.27 10.0 2.1 0.34 9.7 2.1 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Pro_CA PF00484.19 PSC75414.1 - 1.2e-46 158.9 0.0 1.5e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 Carbonic anhydrase 2Fe-2S_Ferredox PF11591.8 PSC75414.1 - 2.1 8.3 4.3 5.3 7.0 0.5 2.6 2 0 0 2 2 2 0 Ferredoxin chloroplastic transit peptide UPF0731 PF14982.6 PSC75415.1 - 0.031 14.4 0.0 0.27 11.5 0.0 2.2 2 0 0 2 2 2 0 UPF0731 family TPR_1 PF00515.28 PSC75416.1 - 8.7e-47 155.1 25.9 4.1e-06 26.4 0.0 9.8 10 0 0 10 10 9 9 Tetratricopeptide repeat TPR_2 PF07719.17 PSC75416.1 - 4.1e-37 123.3 30.9 7.9e-06 25.6 0.5 11.0 10 1 1 11 11 10 9 Tetratricopeptide repeat STI1 PF17830.1 PSC75416.1 - 2.3e-31 107.5 12.9 1.5e-16 60.1 0.6 2.8 3 0 0 3 3 2 2 STI1 domain TPR_11 PF13414.6 PSC75416.1 - 2e-27 94.6 14.3 0.0012 18.5 0.0 8.7 5 2 3 8 8 8 7 TPR repeat TPR_8 PF13181.6 PSC75416.1 - 1.1e-18 65.8 17.4 0.0035 17.4 0.0 9.9 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.6 PSC75416.1 - 3.2e-14 53.0 27.3 3.4e-06 27.3 0.3 8.4 4 3 3 7 7 7 5 Tetratricopeptide repeat TPR_7 PF13176.6 PSC75416.1 - 4.1e-14 51.5 6.6 0.06 13.4 0.0 8.0 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.6 PSC75416.1 - 4.8e-14 52.7 30.7 0.0013 19.4 0.2 8.4 6 1 2 8 8 7 3 Tetratricopeptide repeat TPR_14 PF13428.6 PSC75416.1 - 8.7e-14 51.1 18.8 0.36 11.8 0.0 10.1 6 3 4 10 10 9 3 Tetratricopeptide repeat TPR_19 PF14559.6 PSC75416.1 - 6.6e-11 42.6 11.6 1.3 9.6 0.1 7.5 4 2 2 7 7 7 4 Tetratricopeptide repeat TPR_9 PF13371.6 PSC75416.1 - 3.5e-06 27.1 15.3 0.26 11.5 0.6 5.7 5 1 1 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 PSC75416.1 - 6.7e-05 23.0 4.0 4.9 7.8 0.0 6.5 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 PSC75416.1 - 0.0023 17.8 28.4 1.6 8.7 0.0 9.6 11 0 0 11 11 10 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 PSC75416.1 - 0.0098 15.9 4.7 1.3 9.2 0.2 4.4 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat Hydrolase_4 PF12146.8 PSC75416.1 - 0.017 14.4 0.0 0.18 11.0 0.0 2.4 2 0 0 2 2 2 0 Serine aminopeptidase, S33 SHNi-TPR PF10516.9 PSC75416.1 - 0.12 11.9 0.7 23 4.6 0.0 4.4 4 0 0 4 4 3 0 SHNi-TPR Exo_endo_phos PF03372.23 PSC75416.1 - 0.13 11.8 0.0 0.34 10.4 0.0 1.7 1 1 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family DUF3856 PF12968.7 PSC75416.1 - 0.14 12.2 10.6 0.19 11.8 0.4 4.0 4 1 0 4 4 4 0 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 PSC75416.1 - 0.23 11.7 8.8 4.8 7.5 0.3 4.7 3 2 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 BTAD PF03704.17 PSC75416.1 - 0.68 10.4 15.0 17 5.9 0.1 6.1 4 2 0 5 5 3 0 Bacterial transcriptional activator domain Chorion_3 PF05387.11 PSC75416.1 - 1.6 8.3 9.3 2.9 7.5 3.3 2.6 2 0 0 2 2 2 0 Chorion family 3 TPR_6 PF13174.6 PSC75416.1 - 8.3 7.3 18.6 90 4.0 0.0 8.3 10 1 1 11 11 9 0 Tetratricopeptide repeat FA_desaturase_2 PF03405.14 PSC75417.1 - 1.5e-145 484.1 0.0 1.7e-145 483.9 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Rubrerythrin PF02915.17 PSC75417.1 - 0.013 15.9 0.0 3.1 8.2 0.0 2.5 2 0 0 2 2 2 0 Rubrerythrin FA_desaturase_2 PF03405.14 PSC75418.1 - 1.4e-145 484.2 0.0 1.7e-145 484.0 0.0 1.0 1 0 0 1 1 1 1 Fatty acid desaturase Rubrerythrin PF02915.17 PSC75418.1 - 0.013 15.9 0.0 3 8.2 0.0 2.5 2 0 0 2 2 2 0 Rubrerythrin Voltage_CLC PF00654.20 PSC75419.1 - 2.4e-89 300.1 20.0 2.4e-89 300.1 20.0 2.2 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 PSC75419.1 - 1.5e-13 51.0 1.3 5.2e-06 26.8 0.2 2.6 2 0 0 2 2 2 2 CBS domain Glutaredoxin PF00462.24 PSC75419.1 - 7.4e-09 35.7 0.0 7.1e-06 26.2 0.0 2.7 2 0 0 2 2 2 2 Glutaredoxin Mem_trans PF03547.18 PSC75420.1 - 6.6e-40 136.7 3.4 1.8e-20 72.7 0.9 2.0 2 0 0 2 2 2 2 Membrane transport protein Arm PF00514.23 PSC75420.1 - 0.00078 19.4 0.5 0.0037 17.2 0.0 2.5 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat TFIIA PF03153.13 PSC75420.1 - 3.3 7.6 7.9 4.6 7.1 7.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit tRNA-synt_1 PF00133.22 PSC75421.1 - 3e-226 752.4 0.0 4e-226 752.0 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PSC75421.1 - 9.4e-24 84.1 0.0 1.7e-23 83.3 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA rve PF00665.26 PSC75421.1 - 2.7e-18 66.3 0.0 6.6e-18 65.0 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain tRNA-synt_1g PF09334.11 PSC75421.1 - 2.3e-13 49.7 0.2 0.00037 19.4 0.1 3.6 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 PSC75421.1 - 0.00038 19.9 0.0 0.00065 19.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain rve_3 PF13683.6 PSC75421.1 - 0.014 15.2 0.0 0.057 13.2 0.0 2.1 1 0 0 1 1 1 0 Integrase core domain ANAPC4 PF12896.7 PSC75422.1 - 1.5e-34 119.3 0.0 1.9e-34 118.9 0.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 PSC75422.1 - 1.8e-25 89.1 0.0 9.9e-25 86.7 0.0 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 PSC75422.1 - 0.018 14.6 0.3 0.042 13.4 0.3 1.6 1 0 0 1 1 1 0 PQQ-like domain WD40 PF00400.32 PSC75422.1 - 0.064 14.2 0.0 1.1 10.3 0.0 2.9 3 0 0 3 3 3 0 WD domain, G-beta repeat Peptidase_C48 PF02902.19 PSC75423.1 - 2.3e-32 112.6 0.1 6.7e-32 111.1 0.0 1.8 2 0 0 2 2 2 1 Ulp1 protease family, C-terminal catalytic domain Nop25 PF09805.9 PSC75423.1 - 0.018 15.5 0.9 0.018 15.5 0.9 3.9 5 0 0 5 5 5 0 Nucleolar protein 12 (25kDa) Fez1 PF06818.15 PSC75424.1 - 0.0072 16.8 23.2 0.12 12.9 6.4 2.6 2 0 0 2 2 2 2 Fez1 DUF4763 PF15960.5 PSC75424.1 - 3.7 6.8 13.8 8.5 5.6 0.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4763) TMF_TATA_bd PF12325.8 PSC75424.1 - 5.3 7.3 25.7 4.5 7.5 1.6 4.1 2 2 2 4 4 4 0 TATA element modulatory factor 1 TATA binding TACC_C PF05010.14 PSC75424.1 - 6.9 6.4 25.9 1.4 8.6 1.6 3.5 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Ank_2 PF12796.7 PSC75427.1 - 2e-25 89.2 1.3 2.6e-14 53.5 0.3 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC75427.1 - 3.3e-21 75.4 1.5 3e-06 27.7 0.0 5.3 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC75427.1 - 4.3e-21 74.7 4.0 2.9e-06 27.5 0.1 5.5 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC75427.1 - 3.2e-17 60.8 2.0 0.0053 17.2 0.0 7.1 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 PSC75427.1 - 2.7e-13 49.7 20.3 0.00016 21.9 0.4 7.1 7 0 0 7 7 7 4 Ankyrin repeat Ank_2 PF12796.7 PSC75428.1 - 2e-25 89.2 1.3 2.6e-14 53.5 0.3 4.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC75428.1 - 3.3e-21 75.4 1.5 3e-06 27.7 0.0 5.3 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC75428.1 - 4.3e-21 74.7 4.0 2.9e-06 27.5 0.1 5.5 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC75428.1 - 3.2e-17 60.8 2.0 0.0053 17.2 0.0 7.1 9 0 0 9 9 9 4 Ankyrin repeat Ank PF00023.30 PSC75428.1 - 2.7e-13 49.7 20.3 0.00016 21.9 0.4 7.1 7 0 0 7 7 7 4 Ankyrin repeat SKA1 PF07160.12 PSC75429.1 - 9.2e-56 189.4 0.0 1.1e-55 189.0 0.0 1.0 1 0 0 1 1 1 1 Spindle and kinetochore-associated protein 1 Proteasome PF00227.26 PSC75430.1 - 4.8e-35 120.8 0.0 5.7e-35 120.5 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit RVT_1 PF00078.27 PSC75431.1 - 2.1e-27 96.1 0.0 1.5e-25 90.1 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) SRP54 PF00448.22 PSC75432.1 - 2.1e-75 252.7 0.3 3.6e-75 251.9 0.3 1.4 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 PSC75432.1 - 4.3e-27 94.6 4.4 4.3e-27 94.6 4.4 3.1 3 1 1 4 4 3 1 Signal peptide binding domain SRP54_N PF02881.19 PSC75432.1 - 2.2e-17 63.0 2.9 9.2e-17 61.0 0.2 3.1 3 0 0 3 3 3 1 SRP54-type protein, helical bundle domain CbiA PF01656.23 PSC75432.1 - 6.6e-08 32.7 0.3 1.7e-07 31.3 0.3 1.8 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 PSC75432.1 - 8e-05 22.6 2.4 0.0012 18.8 0.8 2.6 2 1 1 3 3 3 1 AAA domain AAA_30 PF13604.6 PSC75432.1 - 0.0007 19.4 2.3 0.0025 17.6 1.0 2.6 1 1 1 2 2 2 1 AAA domain ParA PF10609.9 PSC75432.1 - 0.00074 19.0 0.0 0.0019 17.7 0.0 1.8 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase Zeta_toxin PF06414.12 PSC75432.1 - 0.0013 18.1 0.1 0.0033 16.7 0.1 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.6 PSC75432.1 - 0.0013 18.9 0.1 0.0033 17.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain ArsA_ATPase PF02374.15 PSC75432.1 - 0.0018 17.5 0.3 0.0018 17.5 0.3 3.5 4 0 0 4 4 4 1 Anion-transporting ATPase cobW PF02492.19 PSC75432.1 - 0.0019 17.8 0.3 0.0042 16.7 0.3 1.5 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 PSC75432.1 - 0.0028 17.4 0.1 0.0083 15.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 PSC75432.1 - 0.0074 16.6 0.0 0.03 14.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain ATPase PF06745.13 PSC75432.1 - 0.0074 15.7 0.0 0.019 14.3 0.0 1.7 1 0 0 1 1 1 1 KaiC APS_kinase PF01583.20 PSC75432.1 - 0.012 15.5 0.1 0.026 14.4 0.1 1.6 1 0 0 1 1 1 0 Adenylylsulphate kinase Antigen_Bd37 PF11641.8 PSC75432.1 - 0.013 15.0 0.4 0.03 13.8 0.4 1.5 1 0 0 1 1 1 0 Glycosylphosphatidylinositol-anchored merozoite surface protein AAA_16 PF13191.6 PSC75432.1 - 0.017 15.5 0.1 0.045 14.1 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain PIF1 PF05970.14 PSC75432.1 - 0.025 13.8 0.1 0.064 12.4 0.0 1.7 2 0 0 2 2 2 0 PIF1-like helicase MeaB PF03308.16 PSC75432.1 - 0.036 13.0 0.1 0.036 13.0 0.1 2.9 3 1 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB 6PF2K PF01591.18 PSC75432.1 - 0.039 13.2 0.2 0.095 12.0 0.0 1.7 2 0 0 2 2 2 0 6-phosphofructo-2-kinase NTPase_1 PF03266.15 PSC75432.1 - 0.045 13.7 1.0 0.26 11.2 0.1 2.3 2 0 0 2 2 2 0 NTPase AAA_17 PF13207.6 PSC75432.1 - 0.048 14.1 0.4 0.048 14.1 0.4 2.4 2 1 0 2 2 2 0 AAA domain MobB PF03205.14 PSC75432.1 - 0.057 13.3 0.2 0.18 11.7 0.2 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 PSC75432.1 - 0.092 13.2 0.1 3 8.3 0.1 2.7 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 PSC75432.1 - 0.098 12.2 3.1 1.4 8.5 3.0 2.7 1 1 0 1 1 1 0 AAA domain Nore1-SARAH PF16517.5 PSC75432.1 - 0.31 11.0 2.1 0.99 9.4 0.8 2.4 2 0 0 2 2 2 0 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain ResIII PF04851.15 PSC75432.1 - 1.7 8.6 4.2 3.1 7.8 1.2 2.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit MEDS PF14417.6 PSC75433.1 - 0.44 10.3 7.2 0.097 12.5 3.6 1.7 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain DUF563 PF04577.14 PSC75434.1 - 1.1e-13 51.9 0.0 1.9e-13 51.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) Sulfotransfer_3 PF13469.6 PSC75434.1 - 6.3e-05 23.4 8.7 0.00035 21.0 0.0 3.5 2 1 0 2 2 2 1 Sulfotransferase family Sulfotransfer_1 PF00685.27 PSC75434.1 - 0.00064 19.3 0.0 0.0014 18.2 0.0 1.5 1 0 0 1 1 1 1 Sulfotransferase domain Red1 PF07964.11 PSC75434.1 - 0.14 10.4 11.0 0.19 9.9 11.0 1.1 1 0 0 1 1 1 0 Rec10 / Red1 Hamartin PF04388.12 PSC75434.1 - 0.51 8.9 9.7 0.68 8.5 9.7 1.1 1 0 0 1 1 1 0 Hamartin protein TFIIA PF03153.13 PSC75434.1 - 0.97 9.4 39.6 1.5 8.7 39.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PA26 PF04636.13 PSC75434.1 - 3.8 6.3 10.1 7.1 5.4 10.1 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Ndc1_Nup PF09531.10 PSC75434.1 - 4.7 5.8 13.9 7.5 5.1 12.5 1.9 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.16 PSC75434.1 - 6.6 6.7 11.0 11 6.0 11.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LAP1C PF05609.12 PSC75434.1 - 6.7 5.7 23.2 9.8 5.1 23.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) RRM_1 PF00076.22 PSC75435.1 - 5.6e-72 237.5 0.1 1.5e-18 66.4 0.0 5.6 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PSC75435.1 - 1e-09 38.0 0.0 0.00021 20.9 0.0 4.5 4 1 0 5 5 5 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PSC75435.1 - 2.1e-08 33.9 0.0 0.00016 21.5 0.0 4.6 5 0 0 5 5 5 1 Occluded RNA-recognition motif RRM_8 PF11835.8 PSC75435.1 - 5.7e-05 23.3 0.1 0.014 15.5 0.0 3.2 3 0 0 3 3 3 1 RRM-like domain RRM_Rrp7 PF17799.1 PSC75435.1 - 0.17 11.6 0.0 8 6.2 0.0 2.8 3 0 0 3 3 3 0 Rrp7 RRM-like N-terminal domain Ribosomal_S6 PF01250.17 PSC75436.1 - 1.1e-19 70.5 0.0 1.4e-19 70.1 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S6 Tam41_Mmp37 PF09139.11 PSC75437.1 - 9.3e-84 281.6 0.0 1.9e-83 280.6 0.0 1.4 1 1 0 1 1 1 1 Phosphatidate cytidylyltransferase, mitochondrial E1-E2_ATPase PF00122.20 PSC75437.1 - 9.3e-49 165.4 0.5 2.4e-48 164.0 0.5 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 PSC75437.1 - 4.2e-42 144.8 11.6 4.2e-42 144.8 11.6 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 PSC75437.1 - 4.1e-06 27.1 0.2 1.4e-05 25.4 0.2 1.9 2 0 0 2 2 2 1 Heavy-metal-associated domain Hydrolase_3 PF08282.12 PSC75437.1 - 2e-05 24.5 0.8 3.6e-05 23.6 0.6 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PSC75437.1 - 0.065 13.6 1.2 0.85 10.0 1.2 3.0 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase MerE PF05052.12 PSC75437.1 - 0.13 12.2 2.5 0.77 9.7 2.5 2.4 1 0 0 1 1 1 0 MerE protein Pyr_redox_2 PF07992.14 PSC75438.1 - 4.1e-41 141.1 0.1 6e-41 140.6 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PSC75438.1 - 1.3e-12 48.0 0.0 3.6e-11 43.5 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 PSC75438.1 - 0.00093 18.6 0.0 0.0085 15.6 0.0 2.3 2 0 0 2 2 2 1 EF hand Pyr_redox_3 PF13738.6 PSC75438.1 - 0.025 13.9 0.0 4.1 6.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase EF-hand_6 PF13405.6 PSC75438.1 - 0.067 13.2 0.0 0.21 11.6 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain EF-hand_7 PF13499.6 PSC75438.1 - 0.069 13.6 0.0 0.18 12.3 0.0 1.6 1 0 0 1 1 1 0 EF-hand domain pair Na_Ca_ex_C PF16494.5 PSC75438.1 - 0.11 13.0 0.0 0.18 12.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain FAD_binding_3 PF01494.19 PSC75438.1 - 0.16 11.2 0.9 5.7 6.1 0.2 2.7 2 1 1 3 3 3 0 FAD binding domain rve PF00665.26 PSC75439.1 - 1.6e-18 67.0 0.0 6.8e-18 65.0 0.0 2.1 1 0 0 1 1 1 1 Integrase core domain Spc7 PF08317.11 PSC75439.1 - 0.0023 16.8 10.0 0.0023 16.8 10.0 9.6 3 3 7 10 10 10 5 Spc7 kinetochore protein TolA_bind_tri PF16331.5 PSC75439.1 - 0.0068 16.5 2.5 0.0068 16.5 2.5 10.3 9 2 0 9 9 9 2 TolA binding protein trimerisation rve_3 PF13683.6 PSC75439.1 - 0.012 15.4 0.0 0.059 13.2 0.0 2.3 1 0 0 1 1 1 0 Integrase core domain DUF713 PF05218.14 PSC75439.1 - 3.7 7.3 6.9 1.2 8.8 2.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF713) TSC22 PF01166.18 PSC75439.1 - 5.9 7.3 21.4 9.1 6.7 0.2 7.7 10 0 0 10 10 10 0 TSC-22/dip/bun family Sortilin-Vps10 PF15902.5 PSC75440.1 - 2.1e-07 30.1 6.0 0.0031 16.4 0.0 3.1 2 1 0 3 3 3 3 Sortilin, neurotensin receptor 3, BNR_6 PF15899.5 PSC75440.1 - 3.9e-06 26.4 0.4 1.6 9.0 0.0 5.5 5 0 0 5 5 5 1 BNR-Asp box repeat PSII_BNR PF14870.6 PSC75440.1 - 0.02 14.2 17.3 0.017 14.4 13.1 2.1 1 1 0 2 2 2 0 Photosynthesis system II assembly factor YCF48 BNR PF02012.20 PSC75440.1 - 0.036 14.0 21.4 1.1 9.5 0.2 5.7 5 0 0 5 5 5 0 BNR/Asp-box repeat Phytase PF02333.15 PSC75440.1 - 0.15 11.0 1.2 0.31 9.9 0.3 1.8 1 1 1 2 2 2 0 Phytase AAA_12 PF13087.6 PSC75442.1 - 5.9e-39 133.8 0.0 9.4e-39 133.1 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 PSC75442.1 - 1.4e-26 93.9 5.8 1.2e-24 87.6 5.8 2.8 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PSC75442.1 - 6.6e-10 39.5 0.0 6e-07 29.9 0.0 3.5 4 0 0 4 4 4 1 AAA domain AAA_30 PF13604.6 PSC75442.1 - 2.2e-07 30.8 0.1 0.00011 22.0 0.0 3.2 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 PSC75442.1 - 5.3e-06 26.2 0.1 0.00011 21.8 0.0 2.3 2 0 0 2 2 2 1 UvrD/REP helicase N-terminal domain DUF2075 PF09848.9 PSC75442.1 - 8.1e-05 22.0 0.3 0.018 14.3 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 PSC75442.1 - 0.007 16.4 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit BSP_II PF05432.11 PSC75442.1 - 0.015 15.0 24.8 0.024 14.4 24.8 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) PhoH PF02562.16 PSC75442.1 - 0.025 14.1 0.1 0.097 12.1 0.1 1.9 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 PSC75442.1 - 0.029 13.7 0.0 0.051 12.9 0.0 1.3 1 0 0 1 1 1 0 KaiC Paf1 PF03985.13 PSC75442.1 - 0.044 12.8 15.2 0.081 11.9 15.2 1.3 1 0 0 1 1 1 0 Paf1 AAA_22 PF13401.6 PSC75442.1 - 0.056 13.7 0.5 0.49 10.7 0.1 2.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 PSC75442.1 - 0.14 12.0 0.0 0.32 10.9 0.0 1.6 1 0 0 1 1 1 0 NACHT domain DEAD PF00270.29 PSC75442.1 - 0.18 11.6 0.3 1.9 8.3 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase CDC45 PF02724.14 PSC75442.1 - 0.48 8.7 12.4 0.97 7.7 12.4 1.4 1 0 0 1 1 1 0 CDC45-like protein Pox_Ag35 PF03286.14 PSC75442.1 - 1.5 8.5 8.6 3.1 7.6 8.6 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein MPP6 PF10175.9 PSC75442.1 - 1.8 9.1 7.0 4 8.0 7.0 1.5 1 0 0 1 1 1 0 M-phase phosphoprotein 6 DUF2052 PF09747.9 PSC75442.1 - 5.4 7.1 22.1 0.7 10.0 16.7 2.0 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Ribosomal_L11_N PF03946.14 PSC75443.1 - 1.6e-28 98.3 1.0 2.5e-28 97.7 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 PSC75443.1 - 1.1e-23 83.5 0.1 1.7e-23 82.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L11, RNA binding domain HSP90 PF00183.18 PSC75445.1 - 3.4e-201 669.6 19.0 5.3e-201 669.0 19.0 1.3 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 PSC75445.1 - 6.7e-13 49.1 0.1 1.3e-12 48.2 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PSC75445.1 - 3e-10 40.0 0.2 9.9e-10 38.4 0.2 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PrmC_N PF17827.1 PSC75445.1 - 0.11 13.1 0.1 0.64 10.7 0.0 2.4 2 0 0 2 2 2 0 PrmC N-terminal domain DUF913 PF06025.12 PSC75445.1 - 5.6 5.8 8.7 33 3.3 5.1 2.5 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DUF4518 PF15008.6 PSC75445.1 - 6.1 5.9 8.3 2.4 7.3 0.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4518) SpoIIP PF07454.11 PSC75445.1 - 6.8 6.1 16.3 1.2 8.5 3.0 3.1 3 0 0 3 3 3 0 Stage II sporulation protein P (SpoIIP) Pkinase PF00069.25 PSC75446.1 - 6.3e-52 176.5 0.0 8.7e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC75446.1 - 2.6e-36 125.2 0.0 3.9e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase OSR1_C PF12202.8 PSC75446.1 - 1.5e-05 25.1 0.1 2.5e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 Oxidative-stress-responsive kinase 1 C-terminal domain Pkinase_fungal PF17667.1 PSC75446.1 - 0.003 16.4 0.1 0.0086 14.9 0.0 1.7 2 0 0 2 2 2 1 Fungal protein kinase SNF5 PF04855.12 PSC75446.1 - 0.017 15.0 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 DUF4391 PF14335.6 PSC75446.1 - 0.3 10.8 0.6 1.9 8.1 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4391) Prefoldin PF02996.17 PSC75447.1 - 6.1e-19 68.1 0.6 7.6e-19 67.8 0.6 1.1 1 0 0 1 1 1 1 Prefoldin subunit RNA_pol_Rpb2_6 PF00562.28 PSC75447.1 - 0.014 14.5 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 Ribosomal_60s PF00428.19 PSC75447.1 - 5.4 7.7 10.4 1.3 9.7 6.1 2.1 3 0 0 3 3 3 0 60s Acidic ribosomal protein PPR_2 PF13041.6 PSC75448.1 - 9.7e-16 57.7 0.0 6.5e-06 26.3 0.0 4.3 4 0 0 4 4 4 2 PPR repeat family PPR PF01535.20 PSC75448.1 - 3.7e-13 48.7 0.0 0.00021 21.3 0.0 5.3 5 0 0 5 5 5 3 PPR repeat PPR_long PF17177.4 PSC75448.1 - 1.3e-11 44.3 0.0 2.7e-08 33.5 0.0 2.5 1 1 1 2 2 2 2 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 PSC75448.1 - 2.3e-08 33.6 0.0 4.7e-05 23.0 0.0 3.1 4 0 0 4 4 4 2 PPR repeat PPR_3 PF13812.6 PSC75448.1 - 4.4e-05 23.5 0.0 0.0022 18.1 0.0 2.9 1 1 3 4 4 4 3 Pentatricopeptide repeat domain Smr PF01713.21 PSC75448.1 - 0.027 14.8 9.2 0.9 9.9 9.2 2.9 1 1 0 1 1 1 0 Smr domain Toxin_YhaV PF11663.8 PSC75448.1 - 0.095 12.8 0.0 4.8 7.2 0.0 2.5 2 0 0 2 2 2 0 Toxin with endonuclease activity, of toxin-antitoxin system KAP PF05804.12 PSC75449.1 - 1.9e-82 277.6 0.0 7.3e-49 166.6 0.0 3.9 3 1 0 3 3 3 3 Kinesin-associated protein (KAP) FliO PF04347.13 PSC75449.1 - 1.4 9.2 4.3 1.1 9.7 0.2 2.9 3 0 0 3 3 3 0 Flagellar biosynthesis protein, FliO DnaJ PF00226.31 PSC75450.1 - 2.5e-19 69.1 0.0 5.1e-19 68.2 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain Ctr PF04145.15 PSC75450.1 - 0.011 16.4 1.0 0.011 16.4 1.0 2.1 1 1 1 2 2 2 0 Ctr copper transporter family FAM176 PF14851.6 PSC75450.1 - 0.011 15.4 0.6 0.011 15.4 0.6 2.2 1 1 1 2 2 2 0 FAM176 family RskA PF10099.9 PSC75450.1 - 0.021 15.2 14.8 0.039 14.2 14.8 1.5 1 0 0 1 1 1 0 Anti-sigma-K factor rskA DUF4834 PF16118.5 PSC75450.1 - 0.032 15.2 5.0 0.032 15.2 5.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 PSC75450.1 - 0.13 11.0 9.8 0.18 10.5 9.8 1.1 1 0 0 1 1 1 0 Presenilin Glt_symporter PF03616.14 PSC75450.1 - 0.14 10.8 0.6 0.23 10.1 0.6 1.3 1 0 0 1 1 1 0 Sodium/glutamate symporter DUF979 PF06166.12 PSC75450.1 - 0.2 10.8 0.2 0.29 10.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF979) Med15 PF09606.10 PSC75450.1 - 0.28 9.8 22.9 0.31 9.7 22.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Hydin_ADK PF17213.3 PSC75450.1 - 1.6 8.9 7.5 2.7 8.2 7.5 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain DUF5349 PF17298.2 PSC75450.1 - 2.3 7.9 11.6 3.4 7.3 11.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5349) PepSY_TM PF03929.16 PSC75450.1 - 7.7 6.1 12.9 0.19 11.4 5.3 2.0 1 1 1 2 2 2 0 PepSY-associated TM region Agenet PF05641.12 PSC75451.1 - 3.5e-18 65.8 0.1 2.1e-13 50.5 0.2 2.4 2 0 0 2 2 2 2 Agenet domain Myb_DNA-bind_6 PF13921.6 PSC75451.1 - 1.1e-05 25.6 0.1 2.5e-05 24.4 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 PSC75451.1 - 6e-05 23.2 0.4 0.00014 22.0 0.4 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF4611 PF15387.6 PSC75451.1 - 1 9.6 5.2 2 8.7 5.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Agenet PF05641.12 PSC75452.1 - 3.2e-18 65.9 0.1 2e-13 50.6 0.2 2.4 2 0 0 2 2 2 2 Agenet domain Myb_DNA-bind_6 PF13921.6 PSC75452.1 - 1.1e-05 25.6 0.1 2.4e-05 24.5 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 PSC75452.1 - 5.7e-05 23.2 0.4 0.00014 22.0 0.4 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain DUF3381 PF11861.8 PSC75452.1 - 0.026 14.3 1.4 0.044 13.6 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) DUF4611 PF15387.6 PSC75452.1 - 1.5 9.1 5.7 2.8 8.2 5.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) UBX PF00789.20 PSC75453.1 - 4e-20 71.8 0.0 7.1e-20 71.0 0.0 1.3 1 0 0 1 1 1 1 UBX domain UBA_4 PF14555.6 PSC75453.1 - 5.1e-08 32.6 0.0 1.1e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain V-ATPase_G_2 PF16999.5 PSC75453.1 - 0.007 16.8 0.2 0.007 16.8 0.2 2.4 2 0 0 2 2 2 1 Vacuolar (H+)-ATPase G subunit CDC45 PF02724.14 PSC75453.1 - 0.089 11.1 2.1 0.11 10.7 2.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Thioredoxin_7 PF13899.6 PSC75453.1 - 0.11 12.6 0.1 0.38 10.9 0.1 1.9 1 0 0 1 1 1 0 Thioredoxin-like Borrelia_P83 PF05262.11 PSC75453.1 - 0.24 9.9 11.1 0.33 9.4 11.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein zf-Dof PF02701.15 PSC75454.1 - 6e-28 96.8 4.8 1.5e-27 95.5 4.8 1.7 1 0 0 1 1 1 1 Dof domain, zinc finger TFIIA PF03153.13 PSC75454.1 - 0.22 11.5 20.9 0.34 10.8 6.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 PSC75454.1 - 1.5 9.2 5.1 4.3 7.7 0.5 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like zf-Dof PF02701.15 PSC75455.1 - 6.1e-28 96.7 4.8 1.5e-27 95.5 4.8 1.7 1 0 0 1 1 1 1 Dof domain, zinc finger TFIIA PF03153.13 PSC75455.1 - 0.23 11.4 20.9 0.35 10.8 6.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 PSC75455.1 - 1.6 9.1 5.1 4.4 7.7 0.5 2.1 2 0 0 2 2 2 0 Enhancer of polycomb-like PspA_IM30 PF04012.12 PSC75457.1 - 8.4e-51 172.7 25.0 1e-50 172.3 25.0 1.1 1 0 0 1 1 1 1 PspA/IM30 family SLATT_4 PF18186.1 PSC75457.1 - 0.013 15.2 1.3 0.014 15.1 0.1 1.7 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 CDC73_N PF16050.5 PSC75457.1 - 0.057 12.7 6.2 0.082 12.2 6.2 1.2 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal DUF4758 PF15950.5 PSC75457.1 - 0.074 13.4 1.4 0.096 13.0 0.2 1.7 2 0 0 2 2 2 0 Putative sperm flagellar membrane protein Csm1_N PF18504.1 PSC75457.1 - 0.41 11.0 10.1 11 6.4 0.0 3.3 3 0 0 3 3 3 0 Csm1 N-terminal domain Spc7 PF08317.11 PSC75457.1 - 0.5 9.2 15.3 0.65 8.8 14.5 1.6 1 1 1 2 2 2 0 Spc7 kinetochore protein Syntaxin-6_N PF09177.11 PSC75457.1 - 0.95 10.1 5.9 5.4 7.6 4.6 2.5 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4407 PF14362.6 PSC75457.1 - 1.3 8.3 13.3 1.9 7.8 13.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Nup88 PF10168.9 PSC75457.1 - 1.8 6.3 7.6 2.4 5.8 7.6 1.2 1 0 0 1 1 1 0 Nuclear pore component Tup_N PF08581.10 PSC75457.1 - 3.9 7.9 9.0 15 6.0 0.1 3.6 4 1 0 4 4 4 0 Tup N-terminal Bestrophin PF01062.21 PSC75458.1 - 1.4e-36 126.4 5.2 5.6e-23 81.8 0.6 2.7 1 1 1 2 2 2 2 Bestrophin, RFP-TM, chloride channel MORN PF02493.20 PSC75459.1 - 4.2e-14 51.5 6.8 0.0024 17.6 0.7 4.5 4 0 0 4 4 4 4 MORN repeat Snapin_Pallidin PF14712.6 PSC75460.1 - 0.32 11.4 4.2 1.1 9.8 0.0 2.8 3 0 0 3 3 3 0 Snapin/Pallidin NUFIP2 PF15293.6 PSC75460.1 - 0.6 9.0 5.6 0.84 8.5 5.6 1.2 1 0 0 1 1 1 0 Nuclear fragile X mental retardation-interacting protein 2 CEP63 PF17045.5 PSC75460.1 - 1 9.2 5.7 7.3 6.4 0.6 2.4 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa DUF4328 PF14219.6 PSC75461.1 - 0.05 13.1 2.8 0.18 11.4 2.8 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) LapA_dom PF06305.11 PSC75461.1 - 1.4 8.8 4.7 1.5 8.7 1.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF1995 PF09353.10 PSC75462.1 - 6.9e-34 117.6 0.0 1e-33 117.0 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1995) MMS1_N PF10433.9 PSC75463.1 - 2.5e-77 260.6 0.0 2.7e-67 227.5 0.0 2.1 1 1 1 2 2 2 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term Snf7 PF03357.21 PSC75463.1 - 4.2e-07 29.7 10.1 7.2e-07 29.0 10.1 1.2 1 0 0 1 1 1 1 Snf7 COX6A PF02046.15 PSC75463.1 - 0.17 12.3 0.2 0.32 11.5 0.2 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIa TT_ORF2 PF02957.15 PSC75465.1 - 1 10.3 3.6 1.9 9.4 3.6 1.6 1 1 0 1 1 1 0 TT viral ORF2 Glyco_transf_92 PF01697.27 PSC75466.1 - 5.5e-17 62.3 0.0 7.6e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PSC75466.1 - 6.9e-13 48.9 0.1 1.7e-12 47.7 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 2 DUF4726 PF15855.5 PSC75466.1 - 0.26 11.5 7.2 2.8 8.2 1.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4726) RRM_1 PF00076.22 PSC75467.1 - 2.5e-15 56.0 0.0 4e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PSC75467.1 - 0.034 14.2 0.9 0.046 13.8 0.0 1.6 2 0 0 2 2 2 0 RNA binding motif Limkain-b1 PF11608.8 PSC75467.1 - 0.11 12.6 0.0 0.31 11.2 0.0 1.8 2 0 0 2 2 2 0 Limkain b1 RRM_8 PF11835.8 PSC75467.1 - 0.14 12.4 0.0 0.21 11.8 0.0 1.2 1 0 0 1 1 1 0 RRM-like domain PTPLA PF04387.14 PSC75468.1 - 1.2e-52 178.0 2.3 1.5e-52 177.6 2.3 1.1 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA FKBP_C PF00254.28 PSC75469.1 - 7.8e-38 128.7 0.0 1.4e-37 127.9 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CytB6-F_Fe-S PF08802.10 PSC75469.1 - 1.1e-12 47.8 1.7 2.8e-12 46.4 1.7 1.8 1 0 0 1 1 1 1 Cytochrome B6-F complex Fe-S subunit Rieske PF00355.26 PSC75469.1 - 1.4e-11 44.1 0.1 2.8e-11 43.2 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain WHAMM-JMY_N PF15920.5 PSC75469.1 - 0.025 14.4 0.6 0.049 13.5 0.6 1.4 1 0 0 1 1 1 0 N-terminal of Junction-mediating and WASP homolog-associated GAS PF13851.6 PSC75470.1 - 7.6e-45 152.7 3.7 7.6e-45 152.7 3.7 3.2 2 1 1 3 3 3 1 Growth-arrest specific micro-tubule binding Csm1_N PF18504.1 PSC75470.1 - 0.024 15.0 0.3 0.024 15.0 0.3 5.7 3 2 5 8 8 8 0 Csm1 N-terminal domain LRR_8 PF13855.6 PSC75471.1 - 0.051 13.3 0.0 3.3 7.6 0.0 2.2 2 0 0 2 2 2 0 Leucine rich repeat Ribosomal_L31 PF01197.18 PSC75472.1 - 4e-17 62.2 0.1 6e-17 61.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L31 ING PF12998.7 PSC75473.1 - 1.9e-16 60.5 0.0 2.8e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Phage_Mu_Gam PF07352.12 PSC75473.1 - 0.17 11.8 0.0 0.46 10.4 0.0 1.7 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein MutS_V PF00488.21 PSC75474.1 - 8.6e-44 149.8 0.0 1.6e-35 122.8 0.0 2.2 2 0 0 2 2 2 2 MutS domain V MutS_III PF05192.18 PSC75474.1 - 1.9e-23 83.7 0.0 3.8e-23 82.7 0.0 1.5 1 1 0 1 1 1 1 MutS domain III DUF3455 PF11937.8 PSC75474.1 - 0.016 15.6 0.0 4.3 7.7 0.0 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF3455) MutS_V PF00488.21 PSC75475.1 - 9.4e-44 149.7 0.0 1.7e-35 122.8 0.0 2.2 2 0 0 2 2 2 2 MutS domain V MutS_III PF05192.18 PSC75475.1 - 2.1e-23 83.6 0.0 4.2e-23 82.6 0.0 1.5 1 1 0 1 1 1 1 MutS domain III DUF3455 PF11937.8 PSC75475.1 - 0.018 15.4 0.0 4.5 7.6 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3455) WD40 PF00400.32 PSC75476.1 - 1.2e-08 35.5 4.6 0.0043 17.9 0.0 5.2 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC75476.1 - 0.001 19.4 0.0 1.7 9.0 0.0 3.7 2 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain LSM PF01423.22 PSC75477.1 - 1.6e-18 66.1 0.5 2.1e-18 65.8 0.5 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 PSC75477.1 - 0.011 15.9 0.3 0.015 15.5 0.3 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Gemin7 PF11095.8 PSC75477.1 - 0.04 13.8 0.1 0.057 13.3 0.1 1.3 1 1 0 1 1 1 0 Gem-associated protein 7 (Gemin7) BPL_C PF02237.17 PSC75477.1 - 0.06 13.3 0.2 0.11 12.4 0.2 1.5 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain WD40 PF00400.32 PSC75478.1 - 1.2e-23 82.9 18.0 6.4e-05 23.7 0.1 7.0 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC75478.1 - 5e-08 33.1 0.1 0.011 16.0 0.0 4.0 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Lipase_GDSL_2 PF13472.6 PSC75478.1 - 1.3e-07 32.2 1.4 2.5e-07 31.3 0.1 2.2 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Pyr_redox_2 PF07992.14 PSC75479.1 - 2.1e-48 165.1 1.1 1.4e-47 162.4 0.8 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PSC75479.1 - 3e-18 66.1 0.1 3.1e-14 52.9 0.0 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin PF00085.20 PSC75479.1 - 1.5e-15 57.1 0.0 2.6e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Pyr_redox PF00070.27 PSC75479.1 - 3e-15 56.5 0.1 9.1e-13 48.6 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thioredoxin_2 PF13098.6 PSC75479.1 - 1.7e-06 28.4 0.0 5.9e-05 23.5 0.0 2.6 2 1 0 2 2 2 1 Thioredoxin-like domain Thi4 PF01946.17 PSC75479.1 - 0.00018 20.8 0.4 0.0008 18.7 0.1 2.0 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 PSC75479.1 - 0.00039 19.9 0.2 0.00039 19.9 0.2 2.7 3 0 0 3 3 2 1 FAD dependent oxidoreductase Thioredoxin_4 PF13462.6 PSC75479.1 - 0.00066 19.9 0.1 0.076 13.2 0.0 2.5 1 1 1 2 2 2 1 Thioredoxin HI0933_like PF03486.14 PSC75479.1 - 0.00082 18.2 0.4 0.016 13.9 0.2 2.5 3 0 0 3 3 3 1 HI0933-like protein FAD_binding_2 PF00890.24 PSC75479.1 - 0.0014 17.8 0.5 0.0014 17.8 0.5 3.0 2 1 0 2 2 2 1 FAD binding domain Glutaredoxin PF00462.24 PSC75479.1 - 0.0027 17.9 0.1 0.0075 16.5 0.1 1.8 1 0 0 1 1 1 1 Glutaredoxin Thioredoxin_3 PF13192.6 PSC75479.1 - 0.012 15.7 0.1 0.082 13.0 0.2 2.2 2 0 0 2 2 2 0 Thioredoxin domain GIDA PF01134.22 PSC75479.1 - 0.023 13.8 0.4 0.023 13.8 0.4 3.8 4 1 0 4 4 4 0 Glucose inhibited division protein A K_oxygenase PF13434.6 PSC75479.1 - 0.028 13.5 0.2 0.43 9.7 0.0 2.5 2 1 1 3 3 3 0 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 PSC75479.1 - 0.03 14.6 6.9 0.069 13.4 0.0 3.6 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain TraF PF13728.6 PSC75479.1 - 0.065 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 F plasmid transfer operon protein NAD_binding_7 PF13241.6 PSC75479.1 - 0.078 13.4 0.1 2.4 8.7 0.0 2.7 2 1 0 2 2 2 0 Putative NAD(P)-binding DUF836 PF05768.14 PSC75479.1 - 0.14 12.6 0.0 1.1 9.7 0.0 2.1 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) DAO PF01266.24 PSC75479.1 - 8.8 5.8 14.4 2.4 7.7 1.0 3.7 4 1 0 5 5 5 0 FAD dependent oxidoreductase CDC45 PF02724.14 PSC75480.1 - 0.18 10.1 1.8 0.24 9.6 1.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Sin_N PF04801.13 PSC75480.1 - 0.87 8.7 2.4 1.2 8.2 2.4 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region zf-CCHC PF00098.23 PSC75481.1 - 6.3e-25 86.1 33.7 1e-07 31.7 3.2 5.6 4 1 0 4 4 4 4 Zinc knuckle zf-GRF PF06839.12 PSC75481.1 - 7.3e-21 74.0 17.4 9.7e-11 41.6 5.0 2.9 2 0 0 2 2 2 2 GRF zinc finger zf-CCHC_3 PF13917.6 PSC75481.1 - 1.8e-11 43.8 20.5 0.001 19.0 1.7 4.8 4 0 0 4 4 4 3 Zinc knuckle zf-CCHC_5 PF14787.6 PSC75481.1 - 6.8e-09 35.3 32.0 0.00086 19.0 3.2 4.7 4 0 0 4 4 4 4 GAG-polyprotein viral zinc-finger zf-CCHC_2 PF13696.6 PSC75481.1 - 8.1e-06 25.6 42.6 0.007 16.2 2.1 5.3 6 0 0 6 6 6 4 Zinc knuckle eIF3g PF12353.8 PSC75481.1 - 0.0001 22.7 16.0 1 9.7 0.9 4.3 4 0 0 4 4 4 4 Eukaryotic translation initiation factor 3 subunit G Ogr_Delta PF04606.12 PSC75481.1 - 0.0072 16.3 12.2 0.38 10.8 2.2 2.9 2 0 0 2 2 2 2 Ogr/Delta-like zinc finger WRKY PF03106.15 PSC75481.1 - 0.028 14.7 4.4 2.4 8.4 0.2 2.6 2 0 0 2 2 2 0 WRKY DNA -binding domain zf-CCHC_4 PF14392.6 PSC75481.1 - 1.6 8.5 9.3 13 5.6 0.4 3.4 3 0 0 3 3 3 0 Zinc knuckle Zn_Tnp_IS1595 PF12760.7 PSC75481.1 - 4.2 7.4 27.2 0.11 12.5 1.1 4.7 6 0 0 6 6 6 0 Transposase zinc-ribbon domain Yippee-Mis18 PF03226.14 PSC75483.1 - 3.3e-05 24.0 3.8 4.4e-05 23.6 3.8 1.2 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Totivirus_coat PF05518.11 PSC75483.1 - 0.11 10.5 0.3 0.11 10.5 0.3 1.1 1 0 0 1 1 1 0 Totivirus coat protein Lipase_3 PF01764.25 PSC75484.1 - 2.6e-25 89.0 0.0 4.4e-25 88.2 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) GRP PF07172.11 PSC75484.1 - 0.00067 20.3 1.6 0.0011 19.7 0.1 2.2 2 0 0 2 2 2 1 Glycine rich protein family Patatin PF01734.22 PSC75485.1 - 2.7e-14 53.8 7.4 8.9e-11 42.3 1.3 2.7 3 0 0 3 3 3 2 Patatin-like phospholipase HEAT PF02985.22 PSC75486.1 - 2.8e-10 39.5 33.1 0.0062 16.7 0.2 10.8 10 1 1 11 11 11 4 HEAT repeat HEAT_2 PF13646.6 PSC75486.1 - 1.3e-06 28.7 38.8 0.19 12.2 2.1 6.6 5 1 0 5 5 5 5 HEAT repeats CSTF1_dimer PF16699.5 PSC75486.1 - 0.064 13.0 1.1 0.32 10.8 0.1 2.7 2 0 0 2 2 2 0 Cleavage stimulation factor subunit 1, dimerisation domain ubiquitin PF00240.23 PSC75488.1 - 2e-170 552.8 24.0 2.5e-33 113.6 0.4 5.4 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 PSC75488.1 - 3.1e-80 264.0 26.2 2.2e-15 56.2 0.5 5.2 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Mito_carr PF00153.27 PSC75488.1 - 3.3e-66 219.3 2.9 1.1e-25 89.4 0.1 3.4 3 0 0 3 3 3 3 Mitochondrial carrier protein Ubiquitin_2 PF14560.6 PSC75488.1 - 1.9e-27 95.5 10.4 0.0011 19.4 0.1 6.5 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 PSC75488.1 - 3.5e-17 62.1 7.4 0.11 12.4 0.1 5.4 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 PSC75488.1 - 3.6e-16 59.3 4.3 0.38 10.9 0.0 6.6 6 0 0 6 6 6 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 PSC75488.1 - 1.8e-15 57.4 1.7 0.75 10.4 0.0 5.4 1 1 0 5 5 5 5 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 PSC75488.1 - 1.8e-15 57.1 13.9 0.05 14.0 0.1 5.6 6 0 0 6 6 5 5 Ubiquitin-like domain DUF3861 PF12977.7 PSC75488.1 - 1.3e-06 28.5 4.4 28 5.0 0.0 5.4 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) UDP-g_GGTase PF06427.11 PSC75488.1 - 8.7e-06 25.8 6.2 15 5.8 0.0 5.2 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase Big_7 PF17957.1 PSC75488.1 - 3.1e-05 24.6 0.2 1.4e+02 3.3 0.0 5.2 5 0 0 5 5 5 0 Bacterial Ig domain ACT_5 PF13710.6 PSC75488.1 - 5.2e-05 23.0 7.7 8.9 6.2 0.1 5.3 5 0 0 5 5 5 1 ACT domain DUF2870 PF11069.8 PSC75488.1 - 8.9e-05 22.8 0.0 1.4e+02 3.0 0.0 5.5 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) Ubiquitin_4 PF18036.1 PSC75488.1 - 0.00018 21.5 32.6 32 4.7 0.2 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain DUF969 PF06149.12 PSC75488.1 - 0.00056 19.4 0.3 61 2.9 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF969) ACT_4 PF13291.6 PSC75488.1 - 0.00065 20.2 2.6 1.4e+02 3.1 0.0 5.2 5 0 0 5 5 5 0 ACT domain ORF11CD3 PF10549.9 PSC75488.1 - 0.094 12.8 0.0 4.1e+02 1.2 0.0 4.7 5 0 0 5 5 5 0 ORF11CD3 domain ProRS-C_2 PF09181.10 PSC75488.1 - 0.2 11.8 9.9 1.5e+02 2.6 0.1 5.3 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal Phage_sheath_1N PF17481.2 PSC75488.1 - 0.63 10.5 10.5 2.3e+02 2.3 0.1 5.0 1 1 0 2 2 2 0 Phage tail sheath protein beta-sandwich domain Tash_PEST PF07708.11 PSC75488.1 - 5.4 7.3 36.0 16 5.8 1.4 5.3 5 0 0 5 5 5 0 Tash protein PEST motif Ank_2 PF12796.7 PSC75489.1 - 2.1e-14 53.9 4.1 2.2e-07 31.3 0.3 4.9 2 1 4 6 6 6 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC75489.1 - 7e-14 52.0 7.2 0.043 14.4 0.1 6.6 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 PSC75489.1 - 8.2e-12 45.0 6.9 0.00031 21.0 0.0 6.6 6 0 0 6 6 6 2 Ankyrin repeat Ank_5 PF13857.6 PSC75489.1 - 8.6e-11 41.9 8.3 3.4e-05 24.0 0.3 5.7 5 1 0 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC75489.1 - 1.7e-08 34.1 6.4 0.0037 17.6 0.0 6.8 7 0 0 7 7 7 1 Ankyrin repeat B3 PF02362.21 PSC75490.1 - 1.3e-06 28.2 0.0 3.1e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 B3 DNA binding domain Ank_2 PF12796.7 PSC75490.1 - 5.9e-06 26.8 0.0 4.6e-05 23.9 0.0 2.2 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PSC75490.1 - 0.0028 18.0 0.0 0.94 10.2 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.6 PSC75490.1 - 0.01 16.1 0.0 0.061 13.7 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC75490.1 - 0.01 16.4 0.0 0.2 12.3 0.0 2.9 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Ank PF00023.30 PSC75490.1 - 0.032 14.7 0.5 0.57 10.7 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeat DUF155 PF02582.14 PSC75491.1 - 2.7e-35 122.0 0.0 3.5e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Sulfate_transp PF00916.20 PSC75492.1 - 3e-11 42.7 17.1 3.6e-11 42.5 16.4 1.4 1 1 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 PSC75492.1 - 0.00012 22.1 0.0 0.00031 20.7 0.0 1.7 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 PSC75492.1 - 0.0017 18.0 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 STAS domain NYN_YacP PF05991.11 PSC75493.1 - 3.1e-14 53.2 0.0 7e-14 52.1 0.0 1.7 1 0 0 1 1 1 1 YacP-like NYN domain 5_3_exonuc_N PF02739.16 PSC75493.1 - 0.068 13.1 0.1 0.23 11.3 0.1 1.9 2 0 0 2 2 2 0 5'-3' exonuclease, N-terminal resolvase-like domain CactinC_cactus PF09732.9 PSC75494.1 - 2.1e-57 192.5 3.7 4.6e-57 191.4 3.7 1.5 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 PSC75494.1 - 1.9e-44 151.7 8.1 1.9e-44 151.7 8.1 2.6 3 0 0 3 3 3 1 Conserved mid region of cactin UQ_con PF00179.26 PSC75494.1 - 5.4e-37 126.6 0.0 1.1e-36 125.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme GST_C_2 PF13410.6 PSC75495.1 - 4.6e-05 23.4 0.1 6.7e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Dzip-like_N PF13815.6 PSC75496.1 - 3.9e-13 49.4 0.2 3.9e-13 49.4 0.2 6.4 5 3 1 6 6 6 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal CENP-F_leu_zip PF10473.9 PSC75496.1 - 7e-05 22.9 4.7 7e-05 22.9 4.7 4.7 3 2 1 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TPD52 PF04201.15 PSC75496.1 - 0.0089 15.7 0.7 0.0089 15.7 0.7 4.0 2 2 2 4 4 4 2 Tumour protein D52 family Band_7 PF01145.25 PSC75496.1 - 0.1 12.6 0.1 0.1 12.6 0.1 4.9 3 2 0 4 4 4 0 SPFH domain / Band 7 family DUF11 PF01345.18 PSC75496.1 - 0.69 10.3 2.7 5.1 7.5 0.5 3.1 2 1 0 2 2 2 0 Domain of unknown function DUF11 SOGA PF11365.8 PSC75496.1 - 9.2 7.5 25.6 0.63 11.2 3.9 5.2 3 2 1 5 5 5 0 Protein SOGA Fib_alpha PF08702.10 PSC75496.1 - 9.5 6.4 9.3 0.41 10.8 0.5 2.9 3 1 0 3 3 3 0 Fibrinogen alpha/beta chain family Dzip-like_N PF13815.6 PSC75497.1 - 3.9e-13 49.4 0.2 3.9e-13 49.4 0.2 6.5 5 3 1 7 7 7 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal CENP-F_leu_zip PF10473.9 PSC75497.1 - 0.00014 21.9 5.8 0.00014 21.9 5.8 4.7 3 2 1 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Band_7 PF01145.25 PSC75497.1 - 0.1 12.6 0.1 0.1 12.6 0.1 4.9 3 2 1 4 4 4 0 SPFH domain / Band 7 family DUF1664 PF07889.12 PSC75497.1 - 0.18 11.9 1.6 5.7 7.0 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) TPD52 PF04201.15 PSC75497.1 - 0.35 10.5 18.4 0.04 13.5 1.6 4.1 2 2 2 4 4 4 0 Tumour protein D52 family DUF11 PF01345.18 PSC75497.1 - 0.72 10.2 2.7 5 7.5 0.5 3.0 2 1 0 2 2 2 0 Domain of unknown function DUF11 Fib_alpha PF08702.10 PSC75497.1 - 2.5 8.3 8.4 0.18 12.0 0.3 2.9 3 1 1 4 4 4 0 Fibrinogen alpha/beta chain family Acetyltransf_1 PF00583.25 PSC75498.1 - 1.5e-05 25.2 0.0 2.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PSC75498.1 - 0.00034 21.0 0.0 0.00065 20.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PSC75498.1 - 0.0011 18.9 0.0 0.0024 17.8 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC75498.1 - 0.0038 17.2 0.0 0.0072 16.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Pkinase PF00069.25 PSC75499.1 - 9.6e-53 179.2 0.0 1.2e-52 178.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC75499.1 - 3.2e-14 52.8 0.0 4.3e-14 52.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EF-hand_6 PF13405.6 PSC75499.1 - 4.3e-09 35.6 0.0 8.4e-05 22.2 0.0 4.3 3 1 1 4 4 4 1 EF-hand domain EF-hand_7 PF13499.6 PSC75499.1 - 6.7e-09 36.1 0.0 0.00064 20.1 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PSC75499.1 - 1.3e-07 30.7 0.3 0.00057 19.2 0.0 4.1 5 0 0 5 5 5 2 EF hand EF-hand_5 PF13202.6 PSC75499.1 - 2.1e-06 27.0 0.0 0.00012 21.4 0.0 2.6 2 0 0 2 2 2 1 EF hand Kinase-like PF14531.6 PSC75499.1 - 0.00027 20.4 0.1 0.16 11.3 0.0 3.1 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 PSC75499.1 - 0.0043 16.4 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PSC75499.1 - 0.054 13.1 0.0 0.56 9.8 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 PSC75499.1 - 0.26 11.2 3.5 2.3 8.1 0.0 3.3 3 1 1 4 4 4 0 Phosphotransferase enzyme family Trypsin PF00089.26 PSC75500.1 - 1.2e-39 136.4 0.0 1.8e-39 135.9 0.0 1.2 1 0 0 1 1 1 1 Trypsin LysM PF01476.20 PSC75500.1 - 0.059 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 LysM domain Copine PF07002.16 PSC75501.1 - 2.9e-68 229.6 0.0 4e-68 229.1 0.0 1.1 1 0 0 1 1 1 1 Copine C2 PF00168.30 PSC75501.1 - 1.1e-18 67.4 0.0 4.1e-14 52.7 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 PSC75501.1 - 8.2e-05 22.8 0.0 0.00014 22.1 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus Ribosomal_60s PF00428.19 PSC75501.1 - 0.45 11.1 2.8 9.6 6.9 1.7 2.4 2 0 0 2 2 2 0 60s Acidic ribosomal protein Acetyltransf_1 PF00583.25 PSC75502.1 - 5.1e-15 55.7 0.1 7.5e-15 55.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PSC75502.1 - 1.5e-08 34.6 0.7 2.2e-08 34.1 0.7 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PSC75502.1 - 3.6e-07 30.5 0.2 5.7e-07 29.9 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC75502.1 - 5.8e-05 23.0 0.1 8.4e-05 22.5 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 PSC75502.1 - 0.00037 20.6 0.5 0.00099 19.2 0.4 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Hox9_act PF04617.13 PSC75502.1 - 0.055 14.2 0.3 0.093 13.5 0.3 1.4 1 1 0 1 1 1 0 Hox9 activation region Herpes_UL47 PF03362.13 PSC75502.1 - 0.069 11.9 0.1 0.092 11.5 0.1 1.1 1 0 0 1 1 1 0 Herpesvirus UL47 protein DnaJ PF00226.31 PSC75503.1 - 8.3e-19 67.5 0.8 1.4e-18 66.7 0.8 1.4 1 0 0 1 1 1 1 DnaJ domain Fer4_13 PF13370.6 PSC75503.1 - 8.7e-15 55.0 2.0 2.4e-14 53.6 2.0 1.8 1 0 0 1 1 1 1 4Fe-4S single cluster domain of Ferredoxin I Fer4_15 PF13459.6 PSC75503.1 - 9.5e-07 29.5 1.3 2.7e-06 28.0 1.3 1.9 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_10 PF13237.6 PSC75503.1 - 5.7e-05 23.1 2.5 0.00011 22.2 2.5 1.5 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 PSC75503.1 - 0.0065 16.5 2.9 0.015 15.3 2.9 1.6 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4_6 PF12837.7 PSC75503.1 - 0.0068 16.4 2.3 0.015 15.3 2.3 1.6 1 0 0 1 1 1 1 4Fe-4S binding domain Fer4 PF00037.27 PSC75503.1 - 0.011 15.5 3.6 0.011 15.5 3.6 2.0 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_9 PF13187.6 PSC75503.1 - 0.013 15.7 2.5 0.03 14.5 2.5 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_21 PF14697.6 PSC75503.1 - 0.016 15.4 0.5 0.016 15.4 0.5 1.9 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 PSC75503.1 - 0.022 15.4 6.0 0.055 14.1 3.5 1.8 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_17 PF13534.6 PSC75503.1 - 0.073 13.6 3.0 0.32 11.6 3.4 1.8 2 0 0 2 2 1 0 4Fe-4S dicluster domain Fer4_8 PF13183.6 PSC75503.1 - 0.11 13.0 3.2 0.32 11.5 3.2 1.8 1 0 0 1 1 1 0 4Fe-4S dicluster domain Fer4_18 PF13746.6 PSC75503.1 - 0.11 12.7 0.3 0.27 11.5 0.3 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain NUC173 PF08161.12 PSC75503.1 - 0.14 11.8 0.2 0.33 10.6 0.2 1.6 1 0 0 1 1 1 0 NUC173 domain Fer4_3 PF12798.7 PSC75503.1 - 0.42 11.7 4.6 1.2 10.3 4.6 1.8 1 0 0 1 1 1 0 4Fe-4S binding domain PAP1 PF08601.10 PSC75503.1 - 1.7 8.3 4.7 2.5 7.7 4.7 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 AFP PF02420.15 PSC75503.1 - 2.2 8.9 4.5 6.9 7.4 4.5 1.8 1 0 0 1 1 1 0 Insect antifreeze protein repeat Fer4_16 PF13484.6 PSC75503.1 - 2.2 9.3 6.9 1.9 9.5 3.7 2.1 1 1 2 3 3 3 0 4Fe-4S double cluster binding domain LRR_4 PF12799.7 PSC75505.1 - 1.7e-05 25.1 1.4 12 6.5 0.0 5.3 1 1 3 4 4 4 3 Leucine Rich repeats (2 copies) Evr1_Alr PF04777.13 PSC75506.1 - 4e-30 104.2 0.3 5.7e-30 103.7 0.3 1.2 1 0 0 1 1 1 1 Erv1 / Alr family LmjF365940-deam PF14421.6 PSC75506.1 - 0.043 13.4 0.2 0.061 12.9 0.2 1.2 1 0 0 1 1 1 0 A distinct subfamily of CDD/CDA-like deaminases Nic96 PF04097.14 PSC75508.1 - 5.8e-79 266.2 0.0 8.4e-79 265.7 0.0 1.2 1 0 0 1 1 1 1 Nup93/Nic96 CSN8_PSD8_EIF3K PF10075.9 PSC75509.1 - 2.7e-28 98.8 0.0 5.6e-28 97.7 0.0 1.5 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 PSC75509.1 - 8.9e-06 25.3 0.1 1.1e-05 25.0 0.1 1.2 1 0 0 1 1 1 1 SAC3/GANP family PCI PF01399.27 PSC75509.1 - 0.015 15.8 0.2 0.41 11.2 0.0 2.3 2 0 0 2 2 2 0 PCI domain Peptidase_C1 PF00112.23 PSC75510.1 - 1.2e-31 110.5 0.6 2.1e-15 57.4 0.1 2.4 2 0 0 2 2 2 2 Papain family cysteine protease Inhibitor_I29 PF08246.12 PSC75510.1 - 1.8e-06 28.3 0.0 2.6e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) NAD_binding_2 PF03446.15 PSC75511.1 - 3.7e-36 124.7 0.2 5.9e-35 120.8 0.2 2.1 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 PSC75511.1 - 2.4e-29 102.1 0.1 5.6e-29 100.9 0.0 1.6 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 PSC75511.1 - 8e-07 29.6 0.1 2e-06 28.3 0.1 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 PSC75511.1 - 0.0002 21.3 0.1 0.00074 19.4 0.4 1.7 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 PSC75511.1 - 0.00026 21.2 0.0 0.00058 20.1 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain 2-Hacid_dh_C PF02826.19 PSC75511.1 - 0.0015 18.0 0.0 0.0026 17.1 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 PSC75511.1 - 0.0042 16.8 0.3 0.023 14.3 0.2 1.9 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA adh_short PF00106.25 PSC75511.1 - 0.03 13.8 0.0 0.051 13.0 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase UDPG_MGDP_dh_N PF03721.14 PSC75511.1 - 0.064 12.8 0.0 0.14 11.7 0.0 1.5 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain Nas2_N PF18265.1 PSC75512.1 - 3.7e-28 97.2 0.1 4.9e-28 96.9 0.1 1.1 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 PSC75512.1 - 8e-07 28.8 0.2 8.3e-06 25.6 0.1 2.5 2 1 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 PSC75512.1 - 4.3e-06 27.0 0.0 1.1e-05 25.6 0.0 1.6 1 0 0 1 1 1 1 PDZ domain PDZ PF00595.24 PSC75512.1 - 0.0022 18.3 0.0 0.005 17.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain DUF4164 PF13747.6 PSC75512.1 - 0.18 12.1 1.8 0.34 11.2 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) DUF3138 PF11336.8 PSC75512.1 - 3.4 6.2 8.9 0.18 10.4 3.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3138) Fcf1 PF04900.12 PSC75513.1 - 2.2e-22 79.3 0.0 3.9e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Fcf1 TFIIA PF03153.13 PSC75513.1 - 4.3 7.2 15.3 5.9 6.8 15.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Sugar_tr PF00083.24 PSC75514.1 - 2.6e-99 333.1 25.1 3.1e-99 332.9 25.1 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PSC75514.1 - 1.5e-22 80.1 54.6 1.9e-21 76.4 40.6 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Ilar_coat PF01787.16 PSC75515.1 - 0.14 11.9 1.2 0.18 11.6 1.2 1.1 1 0 0 1 1 1 0 Ilarvirus coat protein HEAT PF02985.22 PSC75516.1 - 8.8e-13 47.3 12.5 0.036 14.3 0.0 10.0 14 0 0 14 14 14 4 HEAT repeat HEAT_EZ PF13513.6 PSC75516.1 - 2.2e-11 44.0 17.7 1.2e-06 28.9 0.0 9.1 11 0 0 11 11 11 3 HEAT-like repeat IBN_N PF03810.19 PSC75516.1 - 2.8e-11 43.2 1.3 1.5e-08 34.4 0.3 3.5 3 0 0 3 3 3 2 Importin-beta N-terminal domain IFRD PF05004.13 PSC75516.1 - 2e-09 37.0 3.2 0.0026 16.9 0.5 3.7 2 2 0 2 2 2 2 Interferon-related developmental regulator (IFRD) UME PF08064.13 PSC75516.1 - 6.3e-06 26.0 0.3 0.0038 17.1 0.0 4.3 4 1 0 4 4 4 1 UME (NUC010) domain HEAT_2 PF13646.6 PSC75516.1 - 3.5e-05 24.1 11.3 4.1 7.8 0.0 7.1 5 2 1 6 6 6 3 HEAT repeats DUF3385 PF11865.8 PSC75516.1 - 0.014 15.3 4.5 16 5.4 0.1 4.9 3 3 1 5 5 5 0 Domain of unknown function (DUF3385) BACK PF07707.15 PSC75516.1 - 0.028 14.5 0.1 0.95 9.6 0.0 2.8 2 0 0 2 2 2 0 BTB And C-terminal Kelch DIMCO_N PF16844.5 PSC75516.1 - 0.098 13.0 3.5 0.17 12.3 0.3 3.0 2 1 1 3 3 3 0 Dinitrogenase iron-molybdenum cofactor, N-terminal SAE2 PF08573.10 PSC75517.1 - 1.9e-07 32.2 4.6 1.9e-07 32.2 4.6 6.9 5 2 0 5 5 5 1 DNA repair protein endonuclease SAE2/CtIP C-terminus Mce4_CUP1 PF11887.8 PSC75517.1 - 0.55 9.6 14.5 4 6.8 6.8 2.5 1 1 1 2 2 2 0 Cholesterol uptake porter CUP1 of Mce4, putative NPV_P10 PF05531.12 PSC75517.1 - 1.9 9.0 13.7 15 6.2 0.1 4.0 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Rubis-subs-bind PF09273.11 PSC75518.1 - 6.6e-27 94.7 0.0 1.1e-26 94.0 0.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 PSC75518.1 - 0.02 15.3 0.0 0.037 14.4 0.0 1.4 1 1 0 1 1 1 0 SET domain Toprim_4 PF13662.6 PSC75519.1 - 2.3e-18 66.5 0.0 5.6e-18 65.2 0.0 1.7 1 0 0 1 1 1 1 Toprim domain DnaB_C PF03796.15 PSC75519.1 - 1.4e-10 40.9 0.0 3.4e-10 39.7 0.0 1.6 1 1 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_25 PF13481.6 PSC75519.1 - 4.5e-09 36.2 0.7 2e-08 34.0 0.1 2.4 2 1 0 2 2 2 1 AAA domain Toprim_2 PF13155.6 PSC75519.1 - 1.1e-05 25.7 0.1 0.00016 22.0 0.0 2.9 2 0 0 2 2 2 1 Toprim-like Toprim PF01751.22 PSC75519.1 - 0.00035 20.7 0.0 0.00086 19.5 0.0 1.7 1 0 0 1 1 1 1 Toprim domain AAA_22 PF13401.6 PSC75519.1 - 0.035 14.4 0.0 0.19 12.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain Ponericin PF07442.11 PSC75519.1 - 0.077 13.0 0.9 0.4 10.8 0.0 2.7 2 0 0 2 2 2 0 Ponericin AAA_29 PF13555.6 PSC75519.1 - 0.085 12.6 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain TFIIA PF03153.13 PSC75519.1 - 5.3 6.9 40.1 0.024 14.7 18.1 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit MS_channel PF00924.18 PSC75520.1 - 0.0068 16.0 0.0 0.012 15.1 0.0 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel Ysc84 PF04366.12 PSC75521.1 - 4.3e-09 36.2 0.1 9e-09 35.2 0.0 1.6 2 0 0 2 2 2 1 Las17-binding protein actin regulator PALP PF00291.25 PSC75522.1 - 7.1e-65 219.3 3.0 9.3e-65 218.9 3.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme GHMP_kinases_C PF08544.13 PSC75522.1 - 0.34 11.3 0.0 0.34 11.3 0.0 2.8 3 0 0 3 3 3 0 GHMP kinases C terminal Fasciclin PF02469.22 PSC75523.1 - 7.5e-07 29.4 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain EphA2_TM PF14575.6 PSC75523.1 - 0.04 14.8 0.0 0.063 14.2 0.0 1.3 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain LapA_dom PF06305.11 PSC75523.1 - 0.085 12.7 0.5 0.17 11.7 0.5 1.4 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DAP10 PF07213.11 PSC75523.1 - 0.13 12.2 2.1 0.29 11.1 2.1 1.5 1 0 0 1 1 1 0 DAP10 membrane protein FAM199X PF15814.5 PSC75523.1 - 0.21 10.6 0.3 0.38 9.8 0.3 1.3 1 0 0 1 1 1 0 Protein family FAM199X Arm PF00514.23 PSC75524.1 - 0.088 12.9 3.4 1.4 9.1 0.1 4.8 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat ABC2_membrane PF01061.24 PSC75525.1 - 3.4e-63 212.8 62.3 2.4e-37 128.4 27.4 2.8 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 PSC75525.1 - 5.7e-40 137.0 0.0 1.5e-19 70.9 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_25 PF13481.6 PSC75525.1 - 3.3e-08 33.3 1.0 0.0047 16.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 PSC75525.1 - 1.5e-07 31.1 0.4 0.018 14.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 PSC75525.1 - 1.8e-07 31.3 0.7 0.82 9.4 0.1 3.9 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 PSC75525.1 - 4e-07 30.1 2.8 0.0026 17.7 0.1 2.6 3 0 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 PSC75525.1 - 6.5e-06 26.5 0.1 0.054 13.8 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 PSC75525.1 - 8.5e-06 26.2 10.9 0.0013 19.1 0.0 3.5 4 0 0 4 4 3 2 AAA ATPase domain AAA_33 PF13671.6 PSC75525.1 - 5.2e-05 23.4 0.1 0.1 12.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 PSC75525.1 - 8.5e-05 23.1 0.0 0.54 10.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain PDR_assoc PF08370.11 PSC75525.1 - 0.00011 21.9 11.5 0.0015 18.3 0.2 3.3 3 0 0 3 3 2 2 Plant PDR ABC transporter associated AAA_30 PF13604.6 PSC75525.1 - 0.0002 21.2 1.5 0.37 10.5 0.1 2.8 2 0 0 2 2 2 2 AAA domain PDR_CDR PF06422.12 PSC75525.1 - 0.0002 21.2 0.1 0.00071 19.4 0.1 2.0 1 0 0 1 1 1 1 CDR ABC transporter AAA_23 PF13476.6 PSC75525.1 - 0.0003 21.4 0.1 1.1 9.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 PSC75525.1 - 0.0013 18.7 2.6 0.64 9.9 0.1 2.4 2 0 0 2 2 2 2 NACHT domain Rad17 PF03215.15 PSC75525.1 - 0.0016 18.4 0.1 0.22 11.4 0.0 2.4 2 1 0 2 2 2 1 Rad17 P-loop domain MMR_HSR1 PF01926.23 PSC75525.1 - 0.002 18.2 0.1 1.4 9.0 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 PSC75525.1 - 0.003 17.2 1.2 0.74 9.4 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 PSC75525.1 - 0.0034 17.8 0.1 0.94 9.9 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 PSC75525.1 - 0.0092 15.7 0.2 3.4 7.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 PSC75525.1 - 0.011 15.0 0.1 3 7.1 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.14 PSC75525.1 - 0.015 15.3 1.4 1.9 8.5 0.3 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 PSC75525.1 - 0.02 15.3 0.0 2.4 8.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase ABC_trans_N PF14510.6 PSC75525.1 - 0.056 14.1 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 ABC-transporter N-terminal AAA_28 PF13521.6 PSC75525.1 - 0.059 13.6 9.0 0.18 12.0 0.1 2.8 3 0 0 3 3 2 0 AAA domain Ploopntkinase3 PF18751.1 PSC75525.1 - 0.063 13.2 0.1 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 TsaE PF02367.17 PSC75525.1 - 0.089 12.8 1.2 6.9 6.7 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 PSC75525.1 - 0.11 12.2 0.1 1.8 8.2 0.0 2.6 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.9 PSC75525.1 - 0.11 12.2 1.8 5.1 6.8 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 PSC75525.1 - 0.12 12.6 0.1 19 5.5 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 PSC75525.1 - 0.23 11.2 0.3 10 5.8 0.1 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.15 PSC75525.1 - 0.25 11.2 0.7 6.8 6.6 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.6 PSC75525.1 - 0.48 10.7 2.4 8.9 6.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 PSC75525.1 - 3.9 7.9 5.4 6.4 7.2 0.7 2.4 2 0 0 2 2 2 0 AAA domain ABC2_membrane PF01061.24 PSC75526.1 - 3.7e-63 212.8 62.3 2.5e-37 128.4 27.4 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 PSC75526.1 - 6e-40 136.9 0.0 1.5e-19 70.9 0.0 2.3 2 0 0 2 2 2 2 ABC transporter AAA_25 PF13481.6 PSC75526.1 - 3.6e-08 33.2 1.1 0.0048 16.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 PSC75526.1 - 1.5e-07 31.0 0.4 0.019 14.7 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 PSC75526.1 - 1.7e-07 31.3 0.6 0.78 9.5 0.1 3.9 3 1 1 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 PSC75526.1 - 4.2e-07 30.0 2.8 0.0027 17.7 0.1 2.6 3 0 0 3 3 2 2 RsgA GTPase AAA_22 PF13401.6 PSC75526.1 - 6.8e-06 26.4 0.1 0.055 13.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_16 PF13191.6 PSC75526.1 - 1.2e-05 25.7 11.8 0.0013 19.1 0.0 3.7 4 0 0 4 4 4 2 AAA ATPase domain AAA_33 PF13671.6 PSC75526.1 - 5.4e-05 23.4 0.1 0.1 12.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 PSC75526.1 - 8.7e-05 23.1 0.0 0.55 10.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain PDR_assoc PF08370.11 PSC75526.1 - 0.00011 21.8 11.5 0.0015 18.2 0.2 3.3 3 0 0 3 3 2 2 Plant PDR ABC transporter associated AAA_30 PF13604.6 PSC75526.1 - 0.00021 21.1 1.5 0.38 10.4 0.1 2.8 2 0 0 2 2 2 2 AAA domain PDR_CDR PF06422.12 PSC75526.1 - 0.00021 21.1 0.1 0.00072 19.4 0.1 2.0 1 0 0 1 1 1 1 CDR ABC transporter AAA_23 PF13476.6 PSC75526.1 - 0.0003 21.4 0.1 1.1 9.7 0.0 2.2 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 PSC75526.1 - 0.0013 18.7 2.6 0.65 9.9 0.1 2.4 2 0 0 2 2 2 2 NACHT domain Rad17 PF03215.15 PSC75526.1 - 0.0017 18.3 0.1 0.22 11.4 0.1 2.4 2 1 0 2 2 2 1 Rad17 P-loop domain MMR_HSR1 PF01926.23 PSC75526.1 - 0.002 18.2 0.1 1.5 9.0 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase cobW PF02492.19 PSC75526.1 - 0.0032 17.1 1.2 0.75 9.4 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.29 PSC75526.1 - 0.0036 17.7 0.1 0.96 9.9 0.0 2.9 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 PSC75526.1 - 0.0096 15.7 0.2 3.4 7.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.12 PSC75526.1 - 0.011 15.0 0.1 3.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.14 PSC75526.1 - 0.015 15.3 1.4 1.9 8.5 0.3 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 PSC75526.1 - 0.021 15.2 0.0 2.4 8.6 0.0 2.4 2 0 0 2 2 2 0 RNA helicase AAA_28 PF13521.6 PSC75526.1 - 0.021 15.1 7.7 0.18 12.0 0.1 2.9 3 0 0 3 3 2 0 AAA domain ABC_trans_N PF14510.6 PSC75526.1 - 0.055 14.1 0.0 0.11 13.1 0.0 1.5 1 0 0 1 1 1 0 ABC-transporter N-terminal Ploopntkinase3 PF18751.1 PSC75526.1 - 0.06 13.3 0.1 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 TsaE PF02367.17 PSC75526.1 - 0.092 12.7 1.2 7 6.7 0.1 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Viral_helicase1 PF01443.18 PSC75526.1 - 0.12 12.1 0.1 1.8 8.2 0.0 2.6 3 0 0 3 3 3 0 Viral (Superfamily 1) RNA helicase PduV-EutP PF10662.9 PSC75526.1 - 0.12 12.1 1.8 5.2 6.8 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Roc PF08477.13 PSC75526.1 - 0.13 12.5 0.1 19 5.5 0.0 2.3 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 PSC75526.1 - 0.23 11.1 0.3 11 5.8 0.1 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein NTPase_1 PF03266.15 PSC75526.1 - 0.26 11.2 0.7 6.9 6.5 0.0 2.4 2 0 0 2 2 2 0 NTPase AAA_19 PF13245.6 PSC75526.1 - 0.5 10.7 2.4 9 6.6 0.1 2.7 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 PSC75526.1 - 4 7.9 5.4 6.5 7.2 0.7 2.4 2 0 0 2 2 2 0 AAA domain MMS1_N PF10433.9 PSC75527.1 - 1.8e-158 528.2 0.0 2.2e-158 527.9 0.0 1.1 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 PSC75527.1 - 8.5e-91 304.6 0.0 8.7e-90 301.3 0.0 2.3 2 0 0 2 2 2 1 CPSF A subunit region Glycos_transf_1 PF00534.20 PSC75528.1 - 1.3e-11 44.4 0.0 2.8e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 PSC75528.1 - 8.4e-06 26.3 0.0 2.2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 ALG11_N PF15924.5 PSC75528.1 - 0.0018 18.3 0.0 0.0035 17.4 0.0 1.4 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glyco_transf_4 PF13439.6 PSC75528.1 - 0.0083 16.1 1.9 0.016 15.2 0.0 2.5 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Prefoldin_2 PF01920.20 PSC75528.1 - 0.095 12.7 0.2 0.095 12.7 0.2 1.8 2 0 0 2 2 2 0 Prefoldin subunit ERM PF00769.19 PSC75528.1 - 0.91 9.3 12.4 1.4 8.7 12.4 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TPD52 PF04201.15 PSC75528.1 - 1 8.9 6.3 0.14 11.8 0.4 2.2 2 0 0 2 2 2 0 Tumour protein D52 family Pcc1 PF09341.10 PSC75529.1 - 1.6e-19 69.8 0.1 2.2e-19 69.3 0.1 1.2 1 0 0 1 1 1 1 Transcription factor Pcc1 Trypsin_2 PF13365.6 PSC75530.1 - 1.1e-33 117.3 0.4 1.9e-33 116.5 0.4 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 PSC75530.1 - 2.7e-16 60.1 0.0 4.9e-16 59.2 0.0 1.4 1 1 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 PSC75530.1 - 7.7e-14 51.8 0.1 1.7e-13 50.7 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PSC75530.1 - 4.3e-07 29.7 1.0 0.00052 19.8 0.1 2.7 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 PSC75530.1 - 0.0027 18.0 0.5 0.047 14.0 0.5 2.6 1 1 0 1 1 1 1 PDZ domain Tricorn_PDZ PF14685.6 PSC75530.1 - 0.02 14.9 0.1 0.061 13.3 0.1 1.9 1 0 0 1 1 1 0 Tricorn protease PDZ domain Peptidase_S46 PF10459.9 PSC75530.1 - 0.059 12.0 0.6 0.096 11.3 0.2 1.4 2 0 0 2 2 2 0 Peptidase S46 Exo70 PF03081.15 PSC75531.1 - 1.3e-59 202.2 0.0 2e-59 201.5 0.0 1.3 1 0 0 1 1 1 1 Exo70 exocyst complex subunit Sec34 PF04136.15 PSC75531.1 - 0.25 11.2 0.0 0.45 10.4 0.0 1.4 1 0 0 1 1 1 0 Sec34-like family RRM_1 PF00076.22 PSC75532.1 - 1e-17 63.7 0.0 1.9e-06 27.6 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 PSC75532.1 - 0.0027 17.5 0.0 0.18 11.7 0.0 2.3 2 0 0 2 2 2 2 Occluded RNA-recognition motif WD40 PF00400.32 PSC75533.1 - 0.0039 18.0 0.0 9.2 7.3 0.0 3.9 4 0 0 4 4 4 2 WD domain, G-beta repeat RNF111_N PF15303.6 PSC75533.1 - 0.14 11.9 0.2 0.37 10.5 0.2 1.6 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus Kinesin PF00225.23 PSC75534.1 - 2.9e-112 374.9 0.2 4.4e-112 374.3 0.2 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PSC75534.1 - 3.9e-26 91.8 1.5 1e-25 90.5 0.0 2.4 3 0 0 3 3 3 1 Microtubule binding Baculo_PEP_C PF04513.12 PSC75534.1 - 3.1 7.8 19.2 0.25 11.4 2.0 4.9 1 1 1 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus AAA PF00004.29 PSC75535.1 - 3.2e-40 137.6 0.0 7.4e-40 136.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 PSC75535.1 - 9.3e-21 73.7 3.1 1.9e-20 72.7 3.1 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Vps4_C PF09336.10 PSC75535.1 - 7.5e-20 70.7 0.0 2.7e-19 68.9 0.0 2.0 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 PSC75535.1 - 2.1e-06 27.6 0.0 3.6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PSC75535.1 - 4.9e-06 27.0 0.1 0.0023 18.3 0.0 2.8 2 1 0 3 3 3 1 AAA ATPase domain AAA_5 PF07728.14 PSC75535.1 - 6.6e-05 22.9 0.0 0.00027 21.0 0.0 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 PSC75535.1 - 7.1e-05 22.5 0.0 0.00028 20.6 0.0 2.0 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 PSC75535.1 - 0.00012 22.4 0.1 0.0082 16.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 PSC75535.1 - 0.00018 21.3 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 PSC75535.1 - 0.0003 20.1 0.0 0.00049 19.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 PSC75535.1 - 0.00065 19.7 0.0 0.0023 18.0 0.0 1.9 2 0 0 2 2 1 1 AAA domain AAA_2 PF07724.14 PSC75535.1 - 0.0011 19.1 0.0 0.0025 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 PSC75535.1 - 0.0036 16.6 0.0 0.0058 15.9 0.0 1.3 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 PSC75535.1 - 0.0047 17.1 0.0 0.0085 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PSC75535.1 - 0.0052 17.3 0.0 0.011 16.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 PSC75535.1 - 0.007 16.1 0.1 0.017 14.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 PSC75535.1 - 0.0089 16.4 0.0 0.021 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_25 PF13481.6 PSC75535.1 - 0.032 13.8 0.1 0.72 9.4 0.1 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 PSC75535.1 - 0.046 13.1 0.0 0.097 12.0 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.6 PSC75535.1 - 0.051 14.0 0.0 0.15 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 PSC75535.1 - 0.051 13.5 0.0 0.78 9.6 0.0 2.3 1 1 1 2 2 2 0 NACHT domain Parvo_NS1 PF01057.17 PSC75535.1 - 0.07 12.2 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Use1 PF09753.9 PSC75535.1 - 0.085 12.6 0.0 0.2 11.3 0.0 1.6 2 0 0 2 2 2 0 Membrane fusion protein Use1 Torsin PF06309.11 PSC75535.1 - 0.094 12.8 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Torsin ATPase PF06745.13 PSC75535.1 - 0.11 11.8 0.1 9.9 5.4 0.0 2.3 1 1 0 2 2 2 0 KaiC Sigma54_activat PF00158.26 PSC75535.1 - 0.12 12.0 0.0 0.36 10.5 0.0 1.8 1 1 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 PSC75535.1 - 0.12 11.8 0.1 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 PSC75535.1 - 0.13 12.2 0.0 1.6 8.6 0.0 2.4 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea CPT PF07931.12 PSC75535.1 - 0.13 12.1 0.0 0.47 10.3 0.0 1.9 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_7 PF12775.7 PSC75535.1 - 0.16 11.5 0.0 0.33 10.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region TPR_2 PF07719.17 PSC75535.1 - 0.59 10.4 2.2 0.73 10.1 0.3 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat LCIB_C_CA PF18599.1 PSC75536.1 - 2.3e-70 236.3 0.0 3.4e-70 235.8 0.0 1.2 1 0 0 1 1 1 1 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases RRM_1 PF00076.22 PSC75537.1 - 1.2e-17 63.5 0.0 1.7e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) GRP PF07172.11 PSC75537.1 - 0.012 16.3 3.6 0.019 15.6 3.6 1.3 1 0 0 1 1 1 0 Glycine rich protein family RRM_occluded PF16842.5 PSC75537.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.3 1 1 0 1 1 1 0 Occluded RNA-recognition motif Fasciclin PF02469.22 PSC75538.1 - 1.7e-21 76.7 0.0 1.6e-10 41.3 0.0 2.4 2 0 0 2 2 2 2 Fasciclin domain Serpin PF00079.20 PSC75539.1 - 1.5e-64 218.6 0.0 1.6e-63 215.2 0.0 1.9 1 1 0 1 1 1 1 Serpin (serine protease inhibitor) rve PF00665.26 PSC75540.1 - 2.5e-20 72.9 0.0 8.9e-18 64.6 0.0 3.1 2 0 0 2 2 2 2 Integrase core domain rve_3 PF13683.6 PSC75540.1 - 0.0069 16.1 0.2 0.075 12.8 0.0 2.9 2 0 0 2 2 2 1 Integrase core domain DNA_pol_A PF00476.20 PSC75541.1 - 1.3e-51 175.8 0.0 5.5e-25 88.2 0.0 3.0 3 0 0 3 3 3 2 DNA polymerase family A Presenilin PF01080.17 PSC75541.1 - 0.17 10.6 18.8 0.25 10.0 18.8 1.2 1 0 0 1 1 1 0 Presenilin BAF1_ABF1 PF04684.13 PSC75541.1 - 1.1 8.2 15.2 1.7 7.6 15.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Lin-8 PF03353.15 PSC75541.1 - 1.8 8.1 21.3 2.8 7.4 21.3 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Barwin PF00967.17 PSC75542.1 - 0.00045 20.1 2.2 0.00067 19.5 1.6 1.7 1 1 0 1 1 1 1 Barwin family RINGv PF12906.7 PSC75542.1 - 0.0033 17.5 3.0 0.0092 16.1 3.0 1.8 1 0 0 1 1 1 1 RING-variant domain DPBB_1 PF03330.18 PSC75542.1 - 0.063 13.6 0.0 0.15 12.4 0.0 1.7 1 0 0 1 1 1 0 Lytic transglycolase WD40 PF00400.32 PSC75543.1 - 2.4e-12 47.1 0.2 0.0032 18.3 0.0 4.6 4 0 0 4 4 4 3 WD domain, G-beta repeat WD40 PF00400.32 PSC75544.1 - 1.5e-17 63.6 2.8 0.00017 22.3 0.0 6.2 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.8 PSC75544.1 - 8e-06 24.8 0.1 0.01 14.5 0.0 3.3 2 2 1 3 3 3 3 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 PSC75544.1 - 0.0091 16.3 0.1 0.096 13.0 0.0 2.6 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Trypsin PF00089.26 PSC75545.1 - 1.6e-18 67.3 0.0 4.6e-15 56.0 0.0 2.7 1 1 1 2 2 2 2 Trypsin Trypsin_2 PF13365.6 PSC75545.1 - 0.04 14.8 0.0 0.078 13.9 0.0 1.5 1 0 0 1 1 1 0 Trypsin-like peptidase domain adh_short_C2 PF13561.6 PSC75546.1 - 3e-16 59.7 0.1 3.7e-16 59.4 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PSC75546.1 - 1.9e-14 53.5 0.1 2.6e-14 53.1 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PSC75546.1 - 6.4e-06 26.2 2.4 7.7e-06 25.9 0.0 2.0 2 1 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 PSC75546.1 - 0.0042 17.0 0.3 0.0092 15.9 0.1 1.7 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 PSC75546.1 - 0.0051 16.3 0.0 0.0087 15.5 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.13 PSC75546.1 - 0.0084 15.7 0.1 0.013 15.1 0.1 1.3 1 0 0 1 1 1 1 NmrA-like family GDP_Man_Dehyd PF16363.5 PSC75546.1 - 0.11 11.9 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 PSC75546.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein LRR_4 PF12799.7 PSC75547.1 - 4.4e-08 33.3 9.8 0.071 13.6 0.0 7.1 8 1 0 8 8 8 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PSC75547.1 - 2.4e-05 24.0 15.2 3.1 8.1 0.2 9.9 11 0 0 11 11 11 3 Leucine Rich repeat LRR_1 PF00560.33 PSC75547.1 - 0.0021 18.4 9.8 22 6.1 0.1 7.8 10 0 0 10 10 10 1 Leucine Rich Repeat F-box-like PF12937.7 PSC75547.1 - 0.048 13.6 1.0 0.16 11.9 1.0 2.0 1 0 0 1 1 1 0 F-box-like Ion_trans PF00520.31 PSC75548.1 - 1.9e-09 37.2 0.7 3e-09 36.5 0.7 1.3 1 0 0 1 1 1 1 Ion transport protein Ank_2 PF12796.7 PSC75548.1 - 6.3e-06 26.7 0.3 0.019 15.5 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC75548.1 - 3.4e-05 24.3 0.1 0.02 15.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PSC75548.1 - 0.0015 18.9 0.1 0.99 10.0 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.6 PSC75548.1 - 0.11 12.9 0.6 16 6.0 0.2 3.3 3 0 0 3 3 3 0 Ankyrin repeats (many copies) EF-hand_1 PF00036.32 PSC75550.1 - 1.1e-09 37.2 0.0 0.0024 17.3 0.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 PSC75550.1 - 1.3e-09 37.2 0.4 0.0015 18.3 0.0 3.7 2 1 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.6 PSC75550.1 - 4.1e-09 36.7 0.0 1.5e-08 34.9 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 PSC75550.1 - 1.4e-07 30.7 0.3 0.013 15.0 0.0 2.8 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 PSC75550.1 - 2.8e-07 30.3 0.2 0.076 12.9 0.0 3.3 2 1 1 3 3 3 2 EF-hand domain pair EFhand_Ca_insen PF08726.10 PSC75550.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Ca2+ insensitive EF hand DUF4231 PF14015.6 PSC75551.1 - 0.15 12.6 0.5 1.3 9.6 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) Ribosomal_L38e PF01781.18 PSC75552.1 - 5.2e-35 119.4 2.1 5.7e-35 119.2 2.1 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family Ribosomal_L38e PF01781.18 PSC75553.1 - 1.2e-34 118.2 2.1 1.4e-34 118.0 2.1 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family DIOX_N PF14226.6 PSC75554.1 - 1e-29 103.7 0.0 1.5e-29 103.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 PSC75554.1 - 2.7e-22 79.2 0.0 4.9e-22 78.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AAA_assoc_C PF09821.9 PSC75554.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 C-terminal AAA-associated domain Hist_deacetyl PF00850.19 PSC75555.1 - 1.2e-22 80.8 0.0 1.1e-21 77.6 0.1 2.0 1 1 1 2 2 2 1 Histone deacetylase domain BNR_2 PF13088.6 PSC75556.1 - 3.7e-40 138.0 1.7 5.2e-39 134.2 1.7 2.1 1 1 0 1 1 1 1 BNR repeat-like domain Sortilin-Vps10 PF15902.5 PSC75556.1 - 1.4e-08 34.0 0.0 0.00016 20.6 0.0 2.2 2 0 0 2 2 2 2 Sortilin, neurotensin receptor 3, BNR_3 PF13859.6 PSC75556.1 - 9.4e-07 28.4 3.1 4.3e-05 22.9 1.1 3.7 2 1 1 3 3 3 1 BNR repeat-like domain BNR PF02012.20 PSC75556.1 - 0.00038 20.0 19.4 0.6 10.3 0.0 5.6 6 0 0 6 6 6 4 BNR/Asp-box repeat DUF4185 PF13810.6 PSC75556.1 - 0.0016 17.7 2.3 7.2 5.7 0.1 3.6 1 1 3 4 4 4 2 Domain of unknown function (DUF4185) BNR_6 PF15899.5 PSC75556.1 - 0.074 13.1 0.0 2.5 8.4 0.0 3.0 2 0 0 2 2 2 0 BNR-Asp box repeat PSII_BNR PF14870.6 PSC75556.1 - 0.084 12.1 1.2 38 3.4 0.0 3.5 2 2 0 3 3 3 0 Photosynthesis system II assembly factor YCF48 YccV-like PF08755.11 PSC75557.1 - 1.8e-28 98.9 0.0 4.1e-28 97.8 0.0 1.6 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Transglut_core2 PF13369.6 PSC75557.1 - 5.1e-24 84.6 0.0 1.6e-23 83.0 0.0 1.9 1 1 0 1 1 1 1 Transglutaminase-like superfamily F-box-like PF12937.7 PSC75557.1 - 6.1e-09 35.6 5.6 7.9e-08 32.1 0.2 3.2 3 0 0 3 3 3 2 F-box-like F-box PF00646.33 PSC75557.1 - 0.0022 17.8 0.0 0.0054 16.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain UQ_con PF00179.26 PSC75558.1 - 2.1e-40 137.6 0.0 2.7e-40 137.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Cupin_8 PF13621.6 PSC75559.1 - 4.4e-15 56.1 0.1 7.8e-14 52.0 0.0 2.1 1 1 1 2 2 2 1 Cupin-like domain JmjC PF02373.22 PSC75559.1 - 2.7e-10 40.7 0.1 5.3e-10 39.7 0.1 1.5 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_4 PF08007.12 PSC75559.1 - 0.00044 19.8 0.0 0.00089 18.8 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_2 PF07883.11 PSC75559.1 - 0.15 11.8 0.1 0.53 10.0 0.0 1.9 2 0 0 2 2 2 0 Cupin domain Aa_trans PF01490.18 PSC75560.1 - 1.3e-78 264.6 16.3 1.5e-78 264.4 16.3 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Band_7 PF01145.25 PSC75561.1 - 7.6e-20 71.7 0.1 9.7e-20 71.3 0.1 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family CDC50 PF03381.15 PSC75562.1 - 4.1e-58 197.1 0.0 6.7e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CBM_20 PF00686.19 PSC75563.1 - 9.3e-20 70.3 0.0 5e-19 68.0 0.0 2.1 2 0 0 2 2 2 1 Starch binding domain Neur_chan_memb PF02932.16 PSC75563.1 - 1.1e-10 42.0 4.5 8.8e-10 39.0 4.5 2.1 1 1 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region PsbT PF01405.17 PSC75563.1 - 0.14 12.0 0.6 3 7.7 0.4 2.7 2 0 0 2 2 2 0 Photosystem II reaction centre T protein VPS11_C PF12451.8 PSC75564.1 - 2.1e-13 50.2 2.6 2.5e-13 50.0 0.1 2.1 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal Clathrin PF00637.20 PSC75564.1 - 3.6e-08 33.4 0.0 7.8e-06 25.8 0.0 2.5 2 0 0 2 2 2 1 Region in Clathrin and VPS PQQ_2 PF13360.6 PSC75564.1 - 0.0018 17.9 2.9 0.0037 16.9 2.0 1.9 2 0 0 2 2 2 1 PQQ-like domain GAGA PF09237.11 PSC75564.1 - 0.077 12.8 0.1 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 GAGA factor TPR_14 PF13428.6 PSC75564.1 - 0.079 13.8 8.9 2.4 9.2 1.4 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Vps39_2 PF10367.9 PSC75564.1 - 0.1 13.1 0.3 0.22 12.0 0.3 1.5 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 PQQ_3 PF13570.6 PSC75564.1 - 0.41 11.2 10.0 2.1 9.0 0.1 4.0 3 0 0 3 3 3 0 PQQ-like domain IMUP PF15761.5 PSC75564.1 - 3.9 8.2 15.0 11 6.7 15.0 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein Nucleoside_tran PF01733.18 PSC75565.1 - 4.5e-46 157.6 3.9 9.7e-28 97.4 3.6 2.6 2 1 0 2 2 2 2 Nucleoside transporter Pox_A9 PF04835.12 PSC75565.1 - 0.93 9.7 2.4 2.7 8.2 0.1 2.2 2 0 0 2 2 2 0 A9 protein conserved region UbiA PF01040.18 PSC75567.1 - 9.2e-31 107.0 29.5 1.5e-30 106.3 29.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Stig1 PF04885.13 PSC75568.1 - 2.3e-05 24.9 15.5 2.3e-05 24.9 15.5 5.4 2 1 3 5 5 5 2 Stigma-specific protein, Stig1 Stig1 PF04885.13 PSC75569.1 - 4.8e-05 23.9 16.4 4.8e-05 23.9 16.4 5.4 2 1 3 5 5 5 2 Stigma-specific protein, Stig1 Nsp1_C PF05064.13 PSC75571.1 - 3.8e-18 65.4 0.3 7.8e-18 64.4 0.3 1.4 1 0 0 1 1 1 1 Nsp1-like C-terminal region APG6_N PF17675.1 PSC75571.1 - 0.013 16.0 8.3 0.013 16.0 8.3 1.5 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF4515 PF14988.6 PSC75571.1 - 0.013 15.3 4.0 0.034 14.0 2.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4515) DUF724 PF05266.14 PSC75571.1 - 0.061 13.2 0.9 0.096 12.5 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF724) DUF4201 PF13870.6 PSC75571.1 - 0.064 13.0 4.2 0.033 13.9 2.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4201) DUF3450 PF11932.8 PSC75571.1 - 0.091 12.0 4.0 0.083 12.2 2.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF1664 PF07889.12 PSC75571.1 - 0.19 11.8 0.2 5.1 7.1 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) CENP-Q PF13094.6 PSC75571.1 - 2 8.6 9.1 3.3 7.9 9.1 1.3 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DHR10 PF18595.1 PSC75571.1 - 2.9 8.0 9.9 1.1 9.3 4.9 2.5 2 1 1 3 3 3 0 Designed helical repeat protein 10 domain Ribosomal_S27e PF01667.17 PSC75572.1 - 7.5e-27 92.8 6.5 9.5e-27 92.5 6.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 zf-CSL PF05207.13 PSC75572.1 - 0.014 15.1 0.8 0.023 14.4 0.8 1.4 1 0 0 1 1 1 0 CSL zinc finger Prok-RING_1 PF14446.6 PSC75572.1 - 0.037 13.9 3.8 0.062 13.2 3.8 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 IBR PF01485.21 PSC75572.1 - 0.088 13.1 2.2 0.11 12.7 2.2 1.3 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zinc_ribbon_4 PF13717.6 PSC75572.1 - 0.2 11.6 4.4 2.5 8.1 0.5 2.5 2 0 0 2 2 2 0 zinc-ribbon domain zf-RING_7 PF02591.15 PSC75572.1 - 0.63 10.3 6.1 5.8 7.2 0.4 2.5 1 1 1 2 2 2 0 C4-type zinc ribbon domain Eapp_C PF10238.9 PSC75572.1 - 2.3 8.3 5.5 26 4.9 0.1 2.0 1 1 1 2 2 2 0 E2F-associated phosphoprotein LRR_4 PF12799.7 PSC75573.1 - 4.2e-25 87.4 29.7 4.4e-09 36.5 1.1 4.9 2 1 4 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC75573.1 - 3.8e-22 77.8 13.1 2.3e-09 36.9 2.5 3.7 1 1 2 4 4 4 4 Leucine rich repeat LRR_9 PF14580.6 PSC75573.1 - 1.9e-08 34.0 1.4 0.049 13.1 0.4 3.1 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 PSC75573.1 - 3.5e-06 26.8 12.1 19 6.3 0.0 7.5 7 1 0 7 7 7 2 Leucine Rich Repeat LRR_6 PF13516.6 PSC75573.1 - 0.042 13.9 14.8 9.1 6.6 0.0 6.0 6 0 0 6 6 6 0 Leucine Rich repeat CTP_transf_1 PF01148.20 PSC75575.1 - 2.5e-58 198.0 11.6 3e-58 197.7 11.6 1.1 1 0 0 1 1 1 1 Cytidylyltransferase family CDK2AP PF09806.9 PSC75575.1 - 1.3 9.0 7.0 1.9 8.5 7.0 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein zf-AN1 PF01428.16 PSC75576.1 - 1e-17 64.0 31.9 1.7e-10 40.9 4.1 4.6 4 1 1 5 5 5 2 AN1-like Zinc finger zf-Di19 PF05605.12 PSC75576.1 - 6.4e-09 36.0 9.8 0.0043 17.3 0.1 3.9 3 1 0 3 3 3 2 Drought induced 19 protein (Di19), zinc-binding zf-C2H2_4 PF13894.6 PSC75576.1 - 1.9e-08 34.4 19.0 0.0015 19.2 0.8 5.6 5 0 0 5 5 5 2 C2H2-type zinc finger zf-C2H2 PF00096.26 PSC75576.1 - 0.00024 21.4 0.9 0.007 16.8 0.5 5.5 6 0 0 6 6 5 2 Zinc finger, C2H2 type FOXP-CC PF16159.5 PSC75576.1 - 0.0019 18.8 2.5 0.96 10.1 0.0 3.1 3 0 0 3 3 3 2 FOXP coiled-coil domain DUF629 PF04780.12 PSC75576.1 - 0.0034 16.0 0.1 0.31 9.5 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF629) zf-C2H2_6 PF13912.6 PSC75576.1 - 0.0044 17.0 0.1 0.0044 17.0 0.1 3.4 3 0 0 3 3 3 1 C2H2-type zinc finger zf_ZIC PF18366.1 PSC75576.1 - 0.0064 16.6 0.0 3.4 7.9 0.1 2.5 2 0 0 2 2 2 1 Zic proteins zinc finger domain zf-C2H2_3rep PF18868.1 PSC75576.1 - 0.028 15.1 4.5 3.1 8.5 0.0 3.3 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats zf-C2H2_11 PF16622.5 PSC75576.1 - 0.32 10.8 7.8 2.6 7.9 0.0 4.0 4 0 0 4 4 3 0 zinc-finger C2H2-type zf-ribbon_3 PF13248.6 PSC75576.1 - 0.44 10.0 0.1 0.44 10.0 0.1 4.9 5 0 0 5 5 5 0 zinc-ribbon domain zf-C2HE PF16278.5 PSC75576.1 - 0.56 10.7 4.0 56 4.3 0.0 3.4 3 0 0 3 3 3 0 C2HE / C2H2 / C2HC zinc-binding finger FoP_duplication PF13865.6 PSC75576.1 - 1.5 9.4 4.3 2.5 8.7 3.7 1.7 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Rad50_zn_hook PF04423.14 PSC75576.1 - 1.6 8.6 4.4 63 3.5 0.2 3.5 3 0 0 3 3 3 0 Rad50 zinc hook motif zf-C2H2_9 PF16293.5 PSC75576.1 - 2.4 8.1 8.0 4.4 7.2 0.0 3.2 4 0 0 4 4 4 0 C2H2 type zinc-finger (1 copy) zf-C2H2_jaz PF12171.8 PSC75576.1 - 4.7 7.6 8.8 18 5.8 0.0 4.0 4 0 0 4 4 4 0 Zinc-finger double-stranded RNA-binding zf_UBZ PF18439.1 PSC75576.1 - 5 6.8 22.6 1.1 9.0 0.2 4.7 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger IBR PF01485.21 PSC75576.1 - 6 7.2 27.4 16 5.8 8.0 4.6 3 2 0 3 3 3 0 IBR domain, a half RING-finger domain Zn-C2H2_12 PF18112.1 PSC75576.1 - 6.1 7.4 13.4 9.7 6.8 0.6 4.0 4 0 0 4 4 3 0 Autophagy receptor zinc finger-C2H2 domain DUF563 PF04577.14 PSC75577.1 - 1.5e-08 35.1 0.0 2.5e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF563) TPX2_importin PF12214.8 PSC75578.1 - 0.37 11.0 21.3 17 5.6 19.4 3.6 1 1 0 2 2 2 0 Cell cycle regulated microtubule associated protein HA2 PF04408.23 PSC75579.1 - 2.7e-21 75.9 0.0 2.7e-21 75.9 0.0 4.7 3 2 0 3 3 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 PSC75579.1 - 1.4e-19 70.3 0.1 3.2e-19 69.1 0.1 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 PSC75579.1 - 6.5e-15 55.4 0.0 1.7e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 PSC75579.1 - 5.2e-05 23.5 0.1 0.00067 19.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain DEAD PF00270.29 PSC75579.1 - 0.00048 19.9 0.4 0.0014 18.4 0.0 2.0 2 0 0 2 2 1 1 DEAD/DEAH box helicase T2SSE PF00437.20 PSC75579.1 - 0.0012 18.0 0.0 0.0036 16.4 0.0 1.8 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.6 PSC75579.1 - 0.005 17.2 0.0 0.017 15.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain PWI PF01480.17 PSC75579.1 - 0.023 15.0 0.0 0.081 13.2 0.0 2.0 1 0 0 1 1 1 0 PWI domain AAA_25 PF13481.6 PSC75579.1 - 0.026 14.1 0.6 0.087 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 PSC75579.1 - 0.044 13.4 0.1 0.13 11.9 0.1 1.9 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain ATPase PF06745.13 PSC75579.1 - 0.05 12.9 0.0 0.13 11.6 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_7 PF12775.7 PSC75579.1 - 0.12 11.9 0.0 0.32 10.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 PSC75579.1 - 0.26 11.8 0.0 0.26 11.8 0.0 3.0 2 1 0 2 2 1 0 ABC transporter AAA_23 PF13476.6 PSC75579.1 - 0.27 11.7 0.0 0.27 11.7 0.0 4.6 2 1 0 2 2 1 0 AAA domain 2OG-FeII_Oxy_3 PF13640.6 PSC75580.1 - 3e-19 69.7 0.0 4.8e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 PSC75580.1 - 3.8e-07 30.5 0.0 2.8e-06 27.7 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily ShK PF01549.24 PSC75580.1 - 0.099 13.2 15.3 0.11 13.1 11.7 2.8 2 1 0 2 2 2 0 ShK domain-like CLN3 PF02487.17 PSC75581.1 - 1.6e-87 294.2 0.3 2.6e-87 293.5 0.3 1.3 1 1 0 1 1 1 1 CLN3 protein Bestrophin PF01062.21 PSC75582.1 - 1.9e-42 145.7 0.1 2.4e-42 145.3 0.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Sua5_yciO_yrdC PF01300.18 PSC75583.1 - 2e-39 134.9 0.0 2.9e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 Telomere recombination Exo_endo_phos PF03372.23 PSC75583.1 - 1.7e-10 40.8 0.1 6.2e-10 39.0 0.1 2.0 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SCAB-Ig PF16709.5 PSC75583.1 - 3.5e-05 23.8 0.0 7e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Ig domain of plant-specific actin-binding protein Iwr1 PF08574.10 PSC75584.1 - 2.2e-12 47.8 1.0 2.2e-12 47.8 1.0 2.0 1 1 0 1 1 1 1 Transcription factor Iwr1 Ribosomal_60s PF00428.19 PSC75584.1 - 0.031 14.8 4.3 0.031 14.8 4.3 4.8 4 1 0 4 4 4 0 60s Acidic ribosomal protein eIF-5a PF01287.20 PSC75585.1 - 5.9e-28 96.8 0.2 1.1e-27 96.0 0.2 1.4 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold Lipase_3 PF01764.25 PSC75585.1 - 1.2e-10 41.4 0.0 2e-10 40.7 0.0 1.3 1 0 0 1 1 1 1 Lipase (class 3) EFP_N PF08207.12 PSC75585.1 - 0.07 13.2 0.1 0.13 12.3 0.1 1.4 1 0 0 1 1 1 0 Elongation factor P (EF-P) KOW-like domain CAP PF00188.26 PSC75586.1 - 1.2e-22 81.1 0.1 2.9e-22 79.9 0.1 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family TPR_7 PF13176.6 PSC75587.1 - 0.02 14.9 0.1 0.23 11.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat SpoU_methylase PF00588.19 PSC75588.1 - 2.9e-28 98.8 0.0 4.3e-28 98.3 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family Pribosyltran PF00156.27 PSC75590.1 - 3.6e-08 33.1 0.0 6.9e-08 32.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Pribosyltran_N PF13793.6 PSC75590.1 - 1.9e-07 31.0 0.0 2.7e-05 24.1 0.0 2.9 3 0 0 3 3 3 1 N-terminal domain of ribose phosphate pyrophosphokinase SET PF00856.28 PSC75590.1 - 1.3e-06 28.9 0.0 5.7e-06 26.8 0.0 2.0 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 PSC75590.1 - 4.2e-05 24.3 1.2 0.00031 21.4 1.1 2.3 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding Pribosyl_synth PF14572.6 PSC75590.1 - 0.00017 21.7 0.0 0.00032 20.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl synthetase-associated domain HyaE PF07449.11 PSC75590.1 - 0.14 12.1 0.0 0.35 10.8 0.0 1.6 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE Kelch_4 PF13418.6 PSC75591.1 - 2.4e-22 78.7 11.0 0.00048 20.1 0.2 6.3 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 PSC75591.1 - 4.7e-16 58.4 0.7 0.037 14.0 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 PSC75591.1 - 5.4e-15 54.7 12.1 3.9e-06 26.3 0.1 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 PSC75591.1 - 9.4e-12 44.8 4.1 0.062 13.6 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 PSC75591.1 - 1.2e-09 37.7 7.7 0.52 10.4 0.1 5.7 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.6 PSC75591.1 - 3.4e-09 36.8 18.8 0.048 14.0 0.1 6.9 7 1 0 7 7 7 4 Galactose oxidase, central domain Spc29 PF17082.5 PSC75591.1 - 7.7 6.3 21.2 0.46 10.3 13.3 2.1 1 1 1 2 2 2 0 Spindle Pole Component 29 Kelch_4 PF13418.6 PSC75592.1 - 2.8e-22 78.5 10.1 0.00049 20.1 0.2 6.3 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 PSC75592.1 - 1.4e-15 56.9 0.5 0.037 14.0 0.0 6.4 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 PSC75592.1 - 3.2e-15 55.4 10.1 3.9e-06 26.3 0.1 5.4 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 PSC75592.1 - 8.7e-12 44.9 3.3 0.062 13.6 0.0 5.5 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 PSC75592.1 - 1.9e-10 40.3 6.2 0.52 10.4 0.1 5.8 5 0 0 5 5 5 4 Kelch motif Kelch_3 PF13415.6 PSC75592.1 - 2.9e-09 37.0 18.6 0.048 14.0 0.1 6.9 7 1 0 7 7 7 4 Galactose oxidase, central domain Spc29 PF17082.5 PSC75592.1 - 6.8 6.5 21.0 0.44 10.4 13.3 2.1 1 1 1 2 2 2 0 Spindle Pole Component 29 Metallophos PF00149.28 PSC75593.1 - 1.2e-10 42.2 0.1 1.9e-10 41.6 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PSC75593.1 - 1.9e-05 24.9 0.0 6.6e-05 23.2 0.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain TFIIB PF00382.19 PSC75594.1 - 8.5e-28 96.2 2.1 1.5e-15 57.0 0.0 3.3 3 0 0 3 3 3 2 Transcription factor TFIIB repeat BRF1 PF07741.13 PSC75594.1 - 1.1e-24 86.7 1.4 1.1e-24 86.7 1.4 4.0 3 1 0 3 3 3 1 Brf1-like TBP-binding domain TF_Zn_Ribbon PF08271.12 PSC75594.1 - 0.046 13.2 5.1 0.084 12.4 5.1 1.5 1 0 0 1 1 1 0 TFIIB zinc-binding PAT1 PF09770.9 PSC75594.1 - 2.7 6.2 18.2 4 5.6 18.2 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 PSC75594.1 - 5.9 3.9 12.0 8.1 3.4 12.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Spt20 PF12090.8 PSC75594.1 - 8.6 5.9 23.8 17 4.9 23.8 1.4 1 0 0 1 1 1 0 Spt20 family MCM_bind PF09739.9 PSC75594.1 - 9.8 4.5 6.9 15 3.8 6.9 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor HEAT PF02985.22 PSC75595.1 - 1.4e-32 108.9 45.1 0.0036 17.4 0.0 22.8 29 0 0 29 29 22 8 HEAT repeat HEAT_EZ PF13513.6 PSC75595.1 - 1.5e-16 60.5 159.1 0.0019 18.7 0.0 28.0 25 6 7 32 32 29 11 HEAT-like repeat HEAT_2 PF13646.6 PSC75595.1 - 3.2e-15 56.3 132.8 6.4e-05 23.3 0.1 22.1 13 7 7 23 23 22 9 HEAT repeats CLASP_N PF12348.8 PSC75595.1 - 5e-15 55.7 0.0 0.00042 19.9 0.0 8.3 8 1 1 10 10 9 3 CLASP N terminal Cnd1 PF12717.7 PSC75595.1 - 7.9e-15 55.3 0.0 0.007 16.4 0.0 8.1 5 3 2 7 7 7 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 PSC75595.1 - 8e-08 32.8 0.0 0.91 10.2 0.0 8.0 6 2 2 8 8 8 1 Vacuolar 14 Fab1-binding region UME PF08064.13 PSC75595.1 - 1.1e-06 28.5 0.3 2.8 7.9 0.0 7.4 8 1 1 9 9 8 1 UME (NUC010) domain IFRD PF05004.13 PSC75595.1 - 8.7e-06 25.0 6.3 22 4.0 0.0 8.6 7 2 0 8 8 8 0 Interferon-related developmental regulator (IFRD) Adaptin_N PF01602.20 PSC75595.1 - 2.5e-05 23.0 0.0 7.8 4.9 0.0 6.3 7 1 0 8 8 8 1 Adaptin N terminal region ParcG PF10274.9 PSC75595.1 - 9.4e-05 22.6 0.1 4.8 7.3 0.0 5.3 6 1 0 7 7 5 2 Parkin co-regulated protein DUF3437 PF11919.8 PSC75595.1 - 0.0092 15.9 2.0 16 5.5 0.0 6.9 8 0 0 8 8 8 0 Domain of unknown function (DUF3437) Ecm29 PF13001.7 PSC75595.1 - 0.011 14.5 0.0 8.9 4.9 0.0 4.9 6 0 0 6 6 6 0 Proteasome stabiliser RTP1_C1 PF10363.9 PSC75595.1 - 0.013 15.7 0.0 75 3.6 0.0 5.2 5 0 0 5 5 4 0 Required for nuclear transport of RNA pol II C-terminus 1 NUC173 PF08161.12 PSC75595.1 - 0.025 14.3 0.0 9.2 5.9 0.0 4.4 5 0 0 5 5 4 0 NUC173 domain DUF3535 PF12054.8 PSC75595.1 - 0.044 13.0 0.4 2.3e+02 0.8 0.0 5.7 4 2 2 7 7 7 0 Domain of unknown function (DUF3535) DRIM PF07539.12 PSC75595.1 - 0.054 11.8 0.0 9 4.5 0.0 3.4 4 0 0 4 4 4 0 Down-regulated in metastasis Cohesin_HEAT PF12765.7 PSC75595.1 - 0.15 12.4 3.1 98 3.4 0.0 5.7 6 0 0 6 6 5 0 HEAT repeat associated with sister chromatid cohesion Dopey_N PF04118.14 PSC75595.1 - 0.26 10.4 0.0 8.1 5.4 0.0 3.6 7 0 0 7 7 7 0 Dopey, N-terminal MMS19_C PF12460.8 PSC75595.1 - 0.5 9.4 5.7 85 2.1 0.1 6.0 6 2 0 6 6 6 0 RNAPII transcription regulator C-terminal CK2S PF15011.6 PSC75596.1 - 4.1e-29 101.5 1.0 1.3e-28 99.9 0.6 2.2 2 0 0 2 2 2 1 Casein Kinase 2 substrate MA3 PF02847.17 PSC75596.1 - 5.9e-23 81.0 0.0 1.1e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 MA3 domain SCO1-SenC PF02630.14 PSC75596.1 - 9.5e-10 38.5 0.0 2.3e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 SCO1/SenC MIF4G PF02854.19 PSC75596.1 - 4.7e-07 29.7 0.0 1e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 MIF4G domain RR_TM4-6 PF06459.12 PSC75596.1 - 6.2 6.6 5.1 12 5.6 5.1 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF716 PF04819.12 PSC75597.1 - 2e-11 43.7 6.2 2e-11 43.7 6.2 2.0 2 1 0 2 2 2 1 Family of unknown function (DUF716) TFIIF_alpha PF05793.12 PSC75598.1 - 0.00093 17.9 24.7 0.00093 17.9 24.7 3.2 3 0 0 3 3 3 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Nop14 PF04147.12 PSC75598.1 - 0.18 10.0 48.8 0.52 8.5 33.2 2.1 2 0 0 2 2 2 0 Nop14-like family BSP_II PF05432.11 PSC75598.1 - 0.61 9.7 48.6 0.31 10.7 29.7 2.6 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Lin-8 PF03353.15 PSC75598.1 - 1.4 8.5 29.9 0.57 9.7 19.6 2.3 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF4050 PF13259.6 PSC75599.1 - 1e-08 35.7 0.2 5.7e-07 30.0 0.0 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF4050) Thioredoxin PF00085.20 PSC75600.1 - 1.5e-58 195.1 0.2 2e-32 111.2 0.0 3.0 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 PSC75600.1 - 3.4e-25 89.0 0.0 2.6e-15 56.8 0.0 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.6 PSC75600.1 - 1.4e-12 47.6 0.0 6.4e-06 26.3 0.0 3.5 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_2 PF13098.6 PSC75600.1 - 2.5e-09 37.6 3.0 2.4e-06 28.0 0.0 3.7 4 2 0 4 4 4 2 Thioredoxin-like domain OST3_OST6 PF04756.13 PSC75600.1 - 1.8e-08 34.1 0.0 0.00043 19.7 0.0 2.2 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 PSC75600.1 - 1.3e-06 28.3 0.4 0.1 12.6 0.0 3.5 2 1 0 3 3 3 2 AhpC/TSA family Thioredoxin_8 PF13905.6 PSC75600.1 - 1.2e-05 25.5 0.2 1.4 9.3 0.0 4.0 3 1 1 4 4 4 2 Thioredoxin-like ERp29_N PF07912.13 PSC75600.1 - 2.5e-05 24.4 0.6 0.1 12.8 0.0 3.6 4 0 0 4 4 4 2 ERp29, N-terminal domain Redoxin PF08534.10 PSC75600.1 - 4.4e-05 23.2 1.4 0.25 11.0 0.0 3.6 3 1 1 4 4 4 2 Redoxin Thioredoxin_9 PF14595.6 PSC75600.1 - 0.0086 15.9 0.0 0.4 10.5 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin TraF PF13728.6 PSC75600.1 - 1.5 8.6 0.0 1.5 8.6 0.0 2.9 3 0 0 3 3 2 0 F plasmid transfer operon protein Memo PF01875.17 PSC75601.1 - 2.5e-29 102.3 0.0 3.9e-29 101.6 0.0 1.2 1 0 0 1 1 1 1 Memo-like protein SBP PF03110.14 PSC75601.1 - 1.2e-24 86.3 5.5 2.7e-24 85.2 5.5 1.6 1 0 0 1 1 1 1 SBP domain Sugarporin_N PF11471.8 PSC75602.1 - 0.0022 17.9 8.8 0.0022 17.9 8.8 9.4 7 2 1 8 8 6 2 Maltoporin periplasmic N-terminal extension CALCOCO1 PF07888.11 PSC75602.1 - 0.0058 15.6 0.9 0.0058 15.6 0.9 4.7 2 1 2 4 4 2 1 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4201 PF13870.6 PSC75602.1 - 0.0061 16.3 3.9 0.0061 16.3 3.9 8.1 3 1 5 8 8 7 3 Domain of unknown function (DUF4201) DUF4164 PF13747.6 PSC75602.1 - 0.0077 16.5 5.4 0.0077 16.5 5.4 8.7 4 3 6 10 10 6 1 Domain of unknown function (DUF4164) Cep57_CLD_2 PF14197.6 PSC75602.1 - 0.0081 16.2 5.1 0.0081 16.2 5.1 10.4 5 4 3 8 8 6 1 Centrosome localisation domain of PPC89 APG6_N PF17675.1 PSC75602.1 - 0.015 15.8 0.5 0.015 15.8 0.5 7.7 2 1 3 6 6 5 0 Apg6 coiled-coil region DUF4686 PF15742.5 PSC75602.1 - 0.35 10.0 0.0 0.35 10.0 0.0 4.9 2 1 3 5 5 5 0 Domain of unknown function (DUF4686) HMMR_N PF15905.5 PSC75602.1 - 1.4 8.3 65.0 0.046 13.2 18.3 5.3 2 1 3 5 5 5 0 Hyaluronan mediated motility receptor N-terminal Fez1 PF06818.15 PSC75602.1 - 2.5 8.5 87.6 1.9 8.9 0.2 5.5 2 1 3 5 5 5 0 Fez1 GAT PF03127.14 PSC75602.1 - 4.1 7.8 10.2 1.7 9.0 0.1 4.4 4 0 0 4 4 4 0 GAT domain Taxilin PF09728.9 PSC75602.1 - 6.6 5.8 69.2 0.057 12.6 24.7 4.9 2 1 2 4 4 3 0 Myosin-like coiled-coil protein DUF3641 PF12345.8 PSC75603.1 - 7.3e-51 171.7 0.6 1.2e-50 171.1 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3641) Radical_SAM PF04055.21 PSC75603.1 - 4.4e-07 30.4 0.0 7.7e-07 29.6 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 PSC75603.1 - 0.16 12.2 0.0 0.29 11.4 0.0 1.3 1 0 0 1 1 1 0 4Fe-4S single cluster domain RCC1 PF00415.18 PSC75605.1 - 2.7e-71 236.0 30.3 1.2e-14 54.7 0.6 8.4 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PSC75605.1 - 2e-46 154.9 38.7 2.9e-08 33.3 1.3 8.9 9 0 0 9 9 9 8 Regulator of chromosome condensation (RCC1) repeat SUKH-3 PF14433.6 PSC75605.1 - 0.087 13.3 2.2 41 4.6 0.1 4.2 4 1 0 4 4 4 0 SUKH-3 immunity protein KTI12 PF08433.10 PSC75606.1 - 9.7e-58 195.8 0.0 4e-57 193.7 0.0 1.8 1 1 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 PSC75606.1 - 4.2e-12 46.4 1.3 1.4e-11 44.7 0.2 2.3 2 0 0 2 2 2 1 AAA domain APS_kinase PF01583.20 PSC75606.1 - 0.0067 16.3 0.1 0.013 15.3 0.1 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase MipZ PF09140.11 PSC75606.1 - 0.0077 15.5 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 ATPase MipZ CbiA PF01656.23 PSC75606.1 - 0.042 13.9 0.0 0.078 13.0 0.0 1.6 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain UQ_con PF00179.26 PSC75607.1 - 9.9e-16 57.7 0.0 1.1e-15 57.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 PSC75607.1 - 0.0079 16.0 0.0 0.0099 15.7 0.0 1.1 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 PSC75607.1 - 0.013 15.8 0.0 0.014 15.7 0.0 1.2 1 0 0 1 1 1 0 RWD domain PTR2 PF00854.21 PSC75608.1 - 1.2e-112 376.6 1.2 3.5e-112 375.1 1.2 1.7 1 1 0 1 1 1 1 POT family MFS_1 PF07690.16 PSC75608.1 - 8.3e-06 25.0 31.2 0.0013 17.7 31.0 3.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TFIIA PF03153.13 PSC75609.1 - 0.0061 16.6 11.1 0.0086 16.1 11.1 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit LisH PF08513.11 PSC75609.1 - 0.0089 16.0 0.0 0.018 15.0 0.0 1.6 1 0 0 1 1 1 1 LisH Ldh_1_C PF02866.18 PSC75609.1 - 0.12 12.3 1.3 0.19 11.6 1.3 1.3 1 0 0 1 1 1 0 lactate/malate dehydrogenase, alpha/beta C-terminal domain Dimerisation2 PF16864.5 PSC75609.1 - 0.35 10.9 2.0 0.5 10.4 1.0 1.7 2 0 0 2 2 2 0 Dimerisation domain IHABP4_N PF16174.5 PSC75609.1 - 2.7 8.6 8.6 6 7.4 8.6 1.5 1 0 0 1 1 1 0 Intracellular hyaluronan-binding protein 4 N-terminal RWP-RK PF02042.15 PSC75610.1 - 5.5e-19 67.9 0.2 2e-18 66.1 0.1 2.1 2 0 0 2 2 2 1 RWP-RK domain ABC_tran PF00005.27 PSC75610.1 - 6.5e-15 55.9 0.1 3.2e-14 53.6 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 PSC75610.1 - 2e-06 27.9 0.1 0.026 14.3 0.1 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsdA_SigD_bd PF16751.5 PSC75610.1 - 0.0027 17.9 2.2 0.0092 16.2 1.0 2.7 2 0 0 2 2 2 1 Anti-sigma-D factor RsdA to sigma factor binding region AAA_25 PF13481.6 PSC75610.1 - 0.0058 16.2 0.0 0.022 14.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF480 PF04337.12 PSC75610.1 - 0.029 14.5 2.1 0.059 13.5 2.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF480 AAA_29 PF13555.6 PSC75610.1 - 0.055 13.2 0.1 0.14 12.0 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_23 PF13476.6 PSC75610.1 - 0.35 11.4 0.0 0.35 11.4 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 PSC75610.1 - 0.41 10.9 0.0 0.41 10.9 0.0 2.4 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 PSC75610.1 - 0.59 10.5 0.0 0.59 10.5 0.0 3.7 2 1 0 2 2 2 0 AAA ATPase domain THF_DHG_CYH_C PF02882.19 PSC75611.1 - 2.7e-66 221.8 0.4 4.4e-66 221.1 0.1 1.5 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 PSC75611.1 - 9e-44 148.5 0.5 1.4e-43 147.9 0.5 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain OCD_Mu_crystall PF02423.15 PSC75611.1 - 0.038 12.9 0.2 0.062 12.2 0.2 1.3 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family LDcluster4 PF18306.1 PSC75612.1 - 0.21 11.1 6.3 0.31 10.6 6.3 1.2 1 0 0 1 1 1 0 SLOG cluster4 family LRR_4 PF12799.7 PSC75613.1 - 4.9e-16 58.6 5.2 0.011 16.2 0.0 9.6 9 1 1 10 10 10 2 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 PSC75613.1 - 5.3e-09 35.4 15.0 8.2 6.8 0.0 11.9 14 0 0 14 14 14 2 Leucine Rich repeat LRR_1 PF00560.33 PSC75613.1 - 1.3e-05 25.1 7.3 1e+02 4.1 0.0 10.4 12 1 1 13 13 13 0 Leucine Rich Repeat NAD_binding_9 PF13454.6 PSC75613.1 - 0.00038 20.5 1.0 0.001 19.1 1.0 1.7 1 0 0 1 1 1 1 FAD-NAD(P)-binding VASt PF16016.5 PSC75613.1 - 0.0014 19.0 0.0 0.0022 18.4 0.0 1.2 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain LRR_8 PF13855.6 PSC75613.1 - 0.012 15.4 13.7 26 4.7 0.1 8.2 7 4 1 8 8 8 0 Leucine rich repeat Prim_Zn_Ribbon PF08273.12 PSC75613.1 - 1 9.7 3.0 12 6.2 0.1 2.6 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase IGPD PF00475.18 PSC75614.1 - 6.8e-63 211.3 0.7 1.5e-62 210.1 0.7 1.7 1 0 0 1 1 1 1 Imidazoleglycerol-phosphate dehydratase zf-RING_2 PF13639.6 PSC75614.1 - 5e-11 42.8 11.7 8.6e-11 42.0 11.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PSC75614.1 - 1.1e-08 34.8 11.4 1.9e-08 34.0 11.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC75614.1 - 4.2e-08 32.9 10.3 6.9e-08 32.2 10.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC75614.1 - 4.5e-07 29.6 8.3 7.9e-07 28.8 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC75614.1 - 1.2e-05 25.1 8.2 2.2e-05 24.3 8.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PSC75614.1 - 0.00019 21.3 7.1 0.00056 19.9 7.3 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PSC75614.1 - 0.0012 19.0 8.8 0.0022 18.1 8.8 1.5 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 PSC75614.1 - 0.0016 18.2 6.7 0.0029 17.4 6.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 PSC75614.1 - 0.0028 17.7 2.4 0.006 16.6 2.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 PSC75614.1 - 0.0062 16.8 14.8 0.019 15.2 14.8 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 PSC75614.1 - 0.0066 16.3 13.9 0.051 13.4 13.7 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 PSC75614.1 - 0.048 13.4 6.7 0.098 12.4 6.7 1.6 1 0 0 1 1 1 0 RING-like zinc finger DUF1272 PF06906.11 PSC75614.1 - 0.63 10.2 5.4 0.66 10.1 3.8 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF1272) zf-C3HC4_5 PF17121.5 PSC75614.1 - 1.4 8.9 8.6 3.5 7.6 8.6 1.7 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC75615.1 - 8.3e-13 48.4 6.1 1.3e-12 47.8 6.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 PSC75615.1 - 4.7e-09 35.9 6.9 7.6e-09 35.3 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PSC75615.1 - 1.5e-07 31.0 1.7 1.5e-07 31.0 1.7 1.7 2 0 0 2 2 1 1 RING-like zinc finger zf-rbx1 PF12678.7 PSC75615.1 - 6.4e-05 23.2 9.8 0.00022 21.5 9.9 1.8 1 1 1 2 2 2 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PSC75615.1 - 8.6e-05 22.4 3.9 0.00017 21.5 3.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PSC75615.1 - 0.00016 21.5 3.6 0.00026 20.8 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.14 PSC75615.1 - 0.00061 19.6 0.9 0.13 12.1 0.2 2.7 2 0 0 2 2 2 1 Rad50 zinc hook motif zf-ANAPC11 PF12861.7 PSC75615.1 - 0.00068 19.6 1.5 0.0012 18.8 1.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.25 PSC75615.1 - 0.00078 19.3 5.0 0.0013 18.6 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 PSC75615.1 - 0.001 18.8 3.4 0.0019 17.9 3.4 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 PSC75615.1 - 0.001 19.0 4.3 0.0019 18.1 4.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PSC75615.1 - 0.002 17.9 7.7 0.019 14.8 8.1 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 PSC75615.1 - 0.019 15.1 1.3 0.057 13.6 1.3 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain Zn_ribbon_17 PF17120.5 PSC75615.1 - 0.033 13.8 4.0 0.062 12.9 4.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 PSC75615.1 - 0.15 12.2 3.4 0.29 11.3 3.4 1.4 1 0 0 1 1 1 0 RING-variant domain YacG PF03884.14 PSC75615.1 - 0.33 10.7 3.5 4.9 7.0 0.4 2.4 2 0 0 2 2 2 0 DNA gyrase inhibitor YacG UPF0547 PF10571.9 PSC75615.1 - 6.6 6.9 7.4 1.2 9.3 0.2 3.0 4 0 0 4 4 3 0 Uncharacterised protein family UPF0547 Myb_DNA-binding PF00249.31 PSC75617.1 - 0.00039 20.5 0.2 0.00079 19.6 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC75617.1 - 0.0005 20.3 0.2 0.0017 18.6 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF2722 PF10846.8 PSC75617.1 - 0.03 13.3 4.0 0.041 12.8 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Forkhead PF00250.18 PSC75617.1 - 0.031 14.5 0.0 0.13 12.5 0.0 2.0 1 1 0 1 1 1 0 Forkhead domain Spt20 PF12090.8 PSC75617.1 - 0.2 11.3 8.6 0.26 10.9 8.6 1.1 1 0 0 1 1 1 0 Spt20 family SUIM_assoc PF16619.5 PSC75617.1 - 8.9 6.5 16.1 22 5.2 16.1 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 peroxidase PF00141.23 PSC75618.1 - 6.8e-25 88.1 0.0 1.3e-24 87.2 0.0 1.4 1 0 0 1 1 1 1 Peroxidase MFS_1 PF07690.16 PSC75618.1 - 1.3e-23 83.6 45.5 1.3e-23 83.6 45.5 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily MT-A70 PF05063.14 PSC75618.1 - 1.6e-07 31.5 0.0 2.5e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 MT-A70 F-box-like PF12937.7 PSC75618.1 - 0.00027 20.8 1.0 0.00078 19.3 1.0 1.8 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 PSC75618.1 - 0.0015 18.3 2.6 0.023 14.5 0.1 3.2 3 0 0 3 3 3 1 Leucine rich repeat F-box PF00646.33 PSC75618.1 - 0.031 14.2 0.9 0.087 12.7 0.9 1.7 1 0 0 1 1 1 0 F-box domain ATG22 PF11700.8 PSC75618.1 - 2.1 6.9 7.3 0.29 9.7 0.2 2.5 3 0 0 3 3 3 0 Vacuole effluxer Atg22 like SBP PF03110.14 PSC75619.1 - 9.1e-30 102.8 11.7 1.6e-29 102.0 11.7 1.4 1 0 0 1 1 1 1 SBP domain Ank_2 PF12796.7 PSC75619.1 - 0.044 14.4 0.0 0.19 12.3 0.0 2.1 1 1 1 2 2 2 0 Ankyrin repeats (3 copies) WD40 PF00400.32 PSC75620.1 - 1.5e-09 38.3 1.4 1.8e-05 25.4 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF711 PF05167.12 PSC75621.1 - 4.8e-33 114.7 0.0 5.7e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised ACR (DUF711) DUF711 PF05167.12 PSC75622.1 - 4.8e-33 114.7 0.0 5.7e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised ACR (DUF711) DUF711 PF05167.12 PSC75623.1 - 4.8e-33 114.7 0.0 5.7e-33 114.4 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised ACR (DUF711) 2Fe-2S_thioredx PF01257.19 PSC75624.1 - 5.4e-56 188.5 0.1 8.2e-56 187.9 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Biopterin_H PF00351.21 PSC75624.1 - 0.012 14.7 0.2 0.016 14.3 0.2 1.2 1 0 0 1 1 1 0 Biopterin-dependent aromatic amino acid hydroxylase Aa_trans PF01490.18 PSC75625.1 - 5.2e-71 239.5 29.8 8e-71 238.9 29.8 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein FAD_binding_3 PF01494.19 PSC75626.1 - 2e-11 43.7 1.0 0.00022 20.6 0.1 2.8 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 PSC75626.1 - 4.4e-07 29.4 1.2 0.00079 18.7 0.1 1.9 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PSC75626.1 - 0.00025 20.7 0.4 0.026 14.1 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase HI0933_like PF03486.14 PSC75626.1 - 0.00039 19.2 0.1 0.0006 18.6 0.1 1.2 1 0 0 1 1 1 1 HI0933-like protein NAD_binding_9 PF13454.6 PSC75626.1 - 0.0015 18.6 0.2 1.5 8.8 0.2 3.4 3 0 0 3 3 3 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 PSC75626.1 - 0.0025 18.0 0.1 0.0066 16.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.22 PSC75626.1 - 0.0049 16.0 0.2 0.0077 15.4 0.2 1.2 1 0 0 1 1 1 1 Glucose inhibited division protein A Trp_halogenase PF04820.14 PSC75626.1 - 0.007 15.3 0.1 0.83 8.4 0.0 2.4 2 1 0 2 2 2 2 Tryptophan halogenase Pyr_redox PF00070.27 PSC75626.1 - 0.0084 16.7 0.1 0.021 15.4 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 PSC75626.1 - 0.032 13.5 0.1 0.068 12.4 0.1 1.4 1 0 0 1 1 1 0 Thi4 family FAD_oxidored PF12831.7 PSC75626.1 - 0.039 13.3 0.0 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase Nucleotid_trans PF03407.16 PSC75627.1 - 5.8e-32 111.4 0.0 8e-32 110.9 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Histone_H2A_C PF16211.5 PSC75627.1 - 1.3e-18 66.4 2.4 2.4e-18 65.5 2.4 1.5 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 PSC75627.1 - 3e-13 50.3 0.0 4.8e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 PSC75627.1 - 0.00046 20.4 0.0 0.00077 19.7 0.0 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SNRNP27 PF08648.12 PSC75628.1 - 2e-21 75.8 0.4 3.8e-21 74.9 0.4 1.5 1 0 0 1 1 1 1 U4/U6.U5 small nuclear ribonucleoproteins DUF599 PF04654.12 PSC75628.1 - 1.3e-15 57.4 2.7 1.3e-15 57.4 2.7 2.3 3 0 0 3 3 3 1 Protein of unknown function, DUF599 COX6B PF02297.17 PSC75628.1 - 8.9e-14 51.5 0.5 1.6e-13 50.7 0.5 1.3 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb DsbD PF02683.15 PSC75629.1 - 3.2e-42 144.9 10.3 6.2e-34 117.8 4.4 2.1 2 0 0 2 2 2 2 Cytochrome C biogenesis protein transmembrane region DsbD_2 PF13386.6 PSC75629.1 - 1.8e-05 24.8 13.2 1.8e-05 24.8 13.2 2.7 2 2 0 2 2 2 1 Cytochrome C biogenesis protein transmembrane region Cyclin_N PF00134.23 PSC75630.1 - 2.8e-11 43.2 0.1 4.9e-11 42.5 0.1 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 PSC75630.1 - 9.5e-08 32.4 0.0 6.3e-06 26.5 0.0 2.5 2 0 0 2 2 2 1 Cyclin C-terminal domain TFIIB PF00382.19 PSC75630.1 - 1.6e-05 24.8 0.2 9e-05 22.5 0.0 2.5 2 0 0 2 2 2 1 Transcription factor TFIIB repeat RB_B PF01857.20 PSC75630.1 - 0.2 11.7 0.2 0.35 10.9 0.2 1.3 1 0 0 1 1 1 0 Retinoblastoma-associated protein B domain DBR1 PF05011.13 PSC75631.1 - 1.4e-31 109.8 0.0 2.3e-31 109.1 0.0 1.3 1 0 0 1 1 1 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 PSC75631.1 - 8.4e-08 32.9 0.2 1.3e-07 32.4 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 PSC75631.1 - 0.0089 16.2 0.0 0.02 15.1 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Motile_Sperm PF00635.26 PSC75632.1 - 1.3e-28 99.0 0.0 2.5e-28 98.1 0.0 1.4 1 0 0 1 1 1 1 MSP (Major sperm protein) domain Cellulase PF00150.18 PSC75632.1 - 2.2e-18 66.7 1.3 5.7e-11 42.4 0.1 3.6 3 1 0 3 3 3 3 Cellulase (glycosyl hydrolase family 5) Smr PF01713.21 PSC75632.1 - 0.0036 17.6 0.2 30 5.1 0.0 3.8 3 0 0 3 3 3 0 Smr domain Cupin_8 PF13621.6 PSC75632.1 - 0.0073 16.0 0.0 16 5.1 0.0 3.1 3 0 0 3 3 3 1 Cupin-like domain SET PF00856.28 PSC75632.1 - 0.0095 16.3 0.0 0.035 14.5 0.0 2.1 2 0 0 2 2 2 1 SET domain AP_endonuc_2 PF01261.24 PSC75632.1 - 0.014 14.8 3.7 3.1 7.2 0.0 4.7 5 0 0 5 5 5 0 Xylose isomerase-like TIM barrel FerA PF08165.11 PSC75632.1 - 0.022 14.7 0.0 33 4.5 0.0 3.5 3 0 0 3 3 3 0 FerA (NUC095) domain PDEase_I_N PF08499.12 PSC75632.1 - 0.16 11.8 5.0 33 4.4 0.1 3.6 3 0 0 3 3 3 0 3'5'-cyclic nucleotide phosphodiesterase N-terminal DUF4111 PF13427.6 PSC75632.1 - 1.4 9.1 4.7 39 4.5 0.0 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF4111) DHquinase_I PF01487.15 PSC75633.1 - 3.1e-63 214.1 0.0 6.7e-63 213.0 0.0 1.6 2 0 0 2 2 2 1 Type I 3-dehydroquinase Shikimate_dh_N PF08501.11 PSC75633.1 - 6.8e-26 90.3 0.0 1.6e-25 89.1 0.0 1.7 1 0 0 1 1 1 1 Shikimate dehydrogenase substrate binding domain SDH_C PF18317.1 PSC75633.1 - 2.1e-10 40.2 0.1 4.7e-10 39.1 0.1 1.6 1 0 0 1 1 1 1 Shikimate 5'-dehydrogenase C-terminal domain Shikimate_DH PF01488.20 PSC75633.1 - 4.1e-10 39.9 0.2 1.1e-09 38.4 0.1 1.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 PSC75633.1 - 2.7e-05 24.7 2.3 5.4e-05 23.7 0.8 2.3 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 PSC75633.1 - 0.00084 18.7 0.0 0.0019 17.6 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain adh_short PF00106.25 PSC75633.1 - 0.0025 17.3 2.9 0.0031 17.0 1.3 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 PSC75633.1 - 0.0038 17.5 2.9 0.065 13.5 1.1 2.9 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain Pyr_redox_2 PF07992.14 PSC75633.1 - 0.0047 16.2 0.7 0.0087 15.3 0.7 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase IlvN PF07991.12 PSC75633.1 - 0.0097 15.5 0.4 0.024 14.2 0.4 1.7 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain AdoHcyase_NAD PF00670.21 PSC75633.1 - 0.011 15.9 1.6 0.025 14.6 1.6 1.5 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain DNA_pol3_gamma3 PF12169.8 PSC75633.1 - 0.033 14.1 0.4 1.8 8.4 0.1 2.5 2 0 0 2 2 2 0 DNA polymerase III subunits gamma and tau domain III 3HCDH_N PF02737.18 PSC75633.1 - 0.079 12.8 1.5 0.16 11.8 1.5 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain zf-dskA_traR PF01258.17 PSC75634.1 - 0.059 13.3 0.1 0.13 12.2 0.1 1.6 1 0 0 1 1 1 0 Prokaryotic dksA/traR C4-type zinc finger Coatomer_E PF04733.14 PSC75635.1 - 3.8e-86 289.1 0.0 4.4e-86 288.9 0.0 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_12 PF13424.6 PSC75635.1 - 9.5e-06 25.8 0.8 0.0067 16.7 0.2 4.9 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_19 PF14559.6 PSC75635.1 - 1e-05 26.0 8.8 0.00017 22.0 0.0 4.0 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 PSC75635.1 - 1.3e-05 24.9 10.9 0.0011 18.9 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_1 PF00515.28 PSC75635.1 - 2.2e-05 24.1 5.1 0.037 13.8 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_17 PF13431.6 PSC75635.1 - 0.0012 19.1 3.2 0.015 15.6 0.1 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 PSC75635.1 - 0.0017 18.5 1.5 0.51 10.6 0.1 3.0 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 PSC75635.1 - 0.0064 16.1 0.1 0.09 12.5 0.0 2.9 3 0 0 3 3 3 1 TPR repeat TPR_5 PF12688.7 PSC75635.1 - 0.014 15.7 1.0 0.9 9.8 0.1 2.6 2 0 0 2 2 2 0 Tetratrico peptide repeat TPR_14 PF13428.6 PSC75635.1 - 0.027 15.3 0.3 0.027 15.3 0.3 4.5 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 PSC75635.1 - 0.04 14.0 0.0 0.04 14.0 0.0 3.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_16 PF13432.6 PSC75635.1 - 0.054 14.2 0.2 0.054 14.2 0.2 4.7 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_20 PF14561.6 PSC75635.1 - 0.1 13.0 6.1 5.3 7.5 0.2 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat HemY_N PF07219.13 PSC75635.1 - 0.43 10.8 3.8 3 8.1 0.2 2.9 3 0 0 3 3 3 0 HemY protein N-terminus Polyketide_cyc2 PF10604.9 PSC75636.1 - 4.3e-11 43.3 0.0 5.6e-11 42.9 0.0 1.0 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc PF03364.20 PSC75636.1 - 6e-09 36.2 0.0 8.1e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF220 PF02713.14 PSC75636.1 - 0.0089 16.1 0.0 0.016 15.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF220 Erg28 PF03694.13 PSC75636.1 - 0.073 13.5 0.0 0.12 12.8 0.0 1.3 1 0 0 1 1 1 0 Erg28 like protein CFAP91 PF14738.6 PSC75637.1 - 0.00036 20.6 9.3 0.00036 20.6 9.3 2.3 2 1 0 2 2 2 1 Cilia- and flagella-associated protein 91 PC-Esterase PF13839.6 PSC75638.1 - 2.1e-05 24.4 0.6 0.17 11.6 0.0 2.4 2 1 0 2 2 2 2 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Endonuclease_NS PF01223.23 PSC75639.1 - 2.8e-53 181.0 0.0 3.8e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Amino_oxidase PF01593.24 PSC75640.1 - 1.5e-73 248.7 0.0 1.8e-73 248.4 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PSC75640.1 - 1.7e-09 37.7 0.0 4.5e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PSC75640.1 - 4.6e-06 26.5 0.0 9.9e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 PSC75640.1 - 0.0016 17.7 0.4 0.0026 17.0 0.4 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 PSC75640.1 - 0.0026 17.2 0.1 0.0038 16.6 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 PSC75640.1 - 0.0047 16.9 0.1 0.0093 16.0 0.1 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding Trp_halogenase PF04820.14 PSC75640.1 - 0.04 12.8 0.4 0.063 12.1 0.4 1.2 1 0 0 1 1 1 0 Tryptophan halogenase SKN1 PF03935.15 PSC75641.1 - 5e-86 289.1 7.9 4.2e-53 180.5 2.6 2.2 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) Amino_oxidase PF01593.24 PSC75641.1 - 9.9e-20 71.2 0.0 1.6e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PSC75641.1 - 6.3e-11 42.4 1.8 3.6e-10 39.9 1.3 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PSC75641.1 - 1.5e-10 41.2 6.7 1.3e-09 38.1 6.7 2.4 1 1 0 1 1 1 1 FAD dependent oxidoreductase F-box-like PF12937.7 PSC75641.1 - 2.7e-10 40.0 5.7 5.5e-05 23.0 0.3 2.9 2 0 0 2 2 2 2 F-box-like Glyco_hydro_16 PF00722.21 PSC75641.1 - 2e-09 37.2 0.5 9.8e-05 21.9 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 FAD_binding_2 PF00890.24 PSC75641.1 - 8e-07 28.5 18.1 4.7e-05 22.7 3.2 3.6 4 0 0 4 4 4 2 FAD binding domain PAN_4 PF14295.6 PSC75641.1 - 1.7e-05 24.6 1.1 1.7e-05 24.6 1.1 2.3 2 0 0 2 2 2 1 PAN domain Thi4 PF01946.17 PSC75641.1 - 3.8e-05 23.1 0.2 9e-05 21.8 0.2 1.5 1 0 0 1 1 1 1 Thi4 family LRR_8 PF13855.6 PSC75641.1 - 4.4e-05 23.2 3.6 3.4 7.5 0.0 6.4 6 0 0 6 6 6 1 Leucine rich repeat F-box PF00646.33 PSC75641.1 - 7e-05 22.6 5.4 0.068 13.1 0.4 2.7 2 0 0 2 2 2 2 F-box domain PAN_1 PF00024.26 PSC75641.1 - 0.0002 21.2 0.6 0.00049 20.0 0.0 1.9 2 0 0 2 2 1 1 PAN domain LRR_4 PF12799.7 PSC75641.1 - 0.00025 21.4 6.1 2e+02 2.6 0.1 9.4 11 2 1 12 12 10 0 Leucine Rich repeats (2 copies) FAD_binding_3 PF01494.19 PSC75641.1 - 0.00031 20.1 0.4 0.00095 18.5 0.5 1.7 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 PSC75641.1 - 0.00033 19.5 0.1 0.14 10.8 0.8 2.3 2 0 0 2 2 2 2 HI0933-like protein GDI PF00996.18 PSC75641.1 - 0.0004 19.0 0.0 0.0014 17.2 0.1 1.7 2 0 0 2 2 2 1 GDP dissociation inhibitor Pyr_redox_2 PF07992.14 PSC75641.1 - 0.00046 19.5 0.5 0.0015 17.9 0.3 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PSC75641.1 - 0.00071 19.0 2.1 0.00071 19.0 2.1 2.3 3 0 0 3 3 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 PSC75641.1 - 0.0018 18.8 1.0 0.18 12.4 1.4 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 PSC75641.1 - 0.041 12.9 1.6 0.28 10.2 0.8 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein GIDA PF01134.22 PSC75641.1 - 0.12 11.5 1.1 2.1 7.4 1.4 2.2 2 0 0 2 2 2 0 Glucose inhibited division protein A FancD2 PF14631.6 PSC75642.1 - 1.1e-111 374.4 0.0 1.1e-89 301.5 0.0 2.8 2 1 0 2 2 2 2 Fanconi anaemia protein FancD2 nuclease FANCI_S1 PF14675.6 PSC75642.1 - 0.00071 19.2 0.0 0.0013 18.3 0.0 1.3 1 0 0 1 1 1 1 FANCI solenoid 1 FANCI_S2 PF14676.6 PSC75642.1 - 0.0012 19.1 0.0 0.0048 17.2 0.0 2.1 1 1 0 1 1 1 1 FANCI solenoid 2 NACHT PF05729.12 PSC75642.1 - 0.0087 16.0 0.0 0.74 9.7 0.0 2.6 2 0 0 2 2 2 1 NACHT domain HSP70 PF00012.20 PSC75643.1 - 8.4e-265 879.6 17.5 1.2e-264 879.0 17.5 1.2 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 PSC75643.1 - 4.6e-21 75.0 1.6 4.2e-20 71.8 0.2 2.1 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 PSC75643.1 - 3.4e-05 24.2 1.8 0.37 11.2 0.0 3.7 3 0 0 3 3 3 2 Cell division protein FtsA Radial_spoke_3 PF06098.11 PSC75643.1 - 0.0056 16.0 7.5 0.0056 16.0 7.5 1.8 2 0 0 2 2 2 1 Radial spoke protein 3 Hydantoinase_A PF01968.18 PSC75643.1 - 0.0089 15.3 1.2 1.4 8.1 0.2 2.6 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase DDR PF08841.10 PSC75643.1 - 0.019 13.9 0.3 0.41 9.6 0.2 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain BcrAD_BadFG PF01869.20 PSC75643.1 - 0.3 10.6 5.4 47 3.4 0.0 4.0 4 0 0 4 4 4 0 BadF/BadG/BcrA/BcrD ATPase family Sec15 PF04091.12 PSC75644.1 - 8e-16 58.3 0.0 5.2e-07 29.4 0.0 2.3 2 0 0 2 2 2 2 Exocyst complex subunit Sec15-like Vta1 PF04652.16 PSC75644.1 - 0.3 11.0 2.1 0.55 10.2 2.1 1.4 1 0 0 1 1 1 0 Vta1 like VRR_NUC PF08774.11 PSC75645.1 - 4.2e-23 81.5 0.0 9.8e-23 80.3 0.0 1.7 1 0 0 1 1 1 1 VRR-NUC domain HIRAN PF08797.11 PSC75645.1 - 1.8e-08 34.2 0.0 5.1e-08 32.7 0.0 1.8 2 0 0 2 2 2 1 HIRAN domain FANC_SAP PF18081.1 PSC75645.1 - 0.018 15.2 1.1 0.2 11.8 1.1 3.0 1 1 0 1 1 1 0 Fanconi anemia-associated nuclease SAP domain SUIM_assoc PF16619.5 PSC75645.1 - 2.5 8.2 12.2 6 7.0 12.2 1.6 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 PSC75645.1 - 2.5 7.7 9.4 3.9 7.0 9.4 1.2 1 0 0 1 1 1 0 Spt20 family Vps52 PF04129.12 PSC75646.1 - 1.6e-114 383.5 0.0 2.1e-114 383.1 0.0 1.1 1 0 0 1 1 1 1 Vps52 / Sac2 family TspO_MBR PF03073.15 PSC75646.1 - 1.2e-28 99.9 15.0 1.2e-28 99.9 15.0 2.5 2 0 0 2 2 2 1 TspO/MBR family Pkinase PF00069.25 PSC75646.1 - 2e-18 66.7 0.0 1.7e-08 34.2 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC75646.1 - 4.8e-15 55.5 0.1 1e-07 31.5 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Sec3_C PF09763.9 PSC75646.1 - 1.9e-07 29.9 0.0 7.7e-07 27.9 0.1 1.9 2 1 0 2 2 2 1 Exocyst complex component Sec3 Pkinase_fungal PF17667.1 PSC75646.1 - 0.0019 17.0 0.0 0.0032 16.3 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Patatin PF01734.22 PSC75647.1 - 1.3e-23 84.3 2.3 1.9e-23 83.7 0.3 2.2 2 1 0 2 2 2 1 Patatin-like phospholipase DUF3336 PF11815.8 PSC75647.1 - 3.4e-22 78.7 0.0 5.3e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) GHMP_kinases_C PF08544.13 PSC75647.1 - 0.17 12.2 0.9 21 5.5 0.1 3.8 4 0 0 4 4 4 0 GHMP kinases C terminal WD40 PF00400.32 PSC75649.1 - 7.5e-49 162.7 7.2 5.6e-08 33.3 0.0 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat PUL PF08324.11 PSC75649.1 - 1.5e-40 139.2 0.2 2.1e-40 138.7 0.2 1.2 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 PSC75649.1 - 9.5e-36 122.5 0.0 1.6e-35 121.7 0.0 1.4 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) BBS2_Mid PF14783.6 PSC75649.1 - 0.022 14.8 0.0 7.2 6.7 0.0 3.5 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region Nup160 PF11715.8 PSC75649.1 - 0.047 12.3 1.2 33 2.9 0.0 3.8 3 1 1 4 4 4 0 Nucleoporin Nup120/160 GalKase_gal_bdg PF10509.9 PSC75650.1 - 8.4e-22 76.5 0.1 1.6e-21 75.5 0.1 1.5 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_N PF00288.26 PSC75650.1 - 4.5e-14 52.4 0.9 1.3e-13 51.0 0.9 1.9 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 PSC75650.1 - 2.7e-10 40.5 0.2 1.4e-09 38.2 0.2 2.2 1 0 0 1 1 1 1 GHMP kinases C terminal CHD5 PF04420.14 PSC75651.1 - 2.5e-09 37.2 0.1 3e-09 36.9 0.1 1.1 1 0 0 1 1 1 1 CHD5-like protein HemX PF04375.14 PSC75651.1 - 0.013 14.8 1.3 0.016 14.6 1.3 1.0 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase COX16 PF14138.6 PSC75651.1 - 0.11 13.0 0.1 0.19 12.2 0.1 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein COX16 F-box-like PF12937.7 PSC75652.1 - 0.0012 18.6 0.0 0.0035 17.2 0.0 1.9 1 0 0 1 1 1 1 F-box-like rve_3 PF13683.6 PSC75652.1 - 0.067 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain LRR_4 PF12799.7 PSC75652.1 - 0.1 13.1 0.5 2.4 8.7 0.2 3.3 3 1 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC75652.1 - 0.13 12.1 0.2 6.3 6.6 0.1 3.3 3 0 0 3 3 3 0 Leucine rich repeat p31comet PF06581.12 PSC75653.1 - 1.1e-11 44.4 0.1 2.1e-11 43.5 0.0 1.4 2 0 0 2 2 2 1 Mad1 and Cdc20-bound-Mad2 binding AUX_IAA PF02309.16 PSC75654.1 - 0.0001 22.2 0.0 0.0001 22.2 0.0 3.7 2 1 0 2 2 2 1 AUX/IAA family Ribosomal_L32e PF01655.18 PSC75655.1 - 7.3e-30 103.6 0.1 8.3e-30 103.4 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L32 Trp_Tyr_perm PF03222.13 PSC75656.1 - 1.4e-69 235.0 26.1 2.2e-69 234.4 26.1 1.1 1 0 0 1 1 1 1 Tryptophan/tyrosine permease family Pox_A_type_inc PF04508.12 PSC75656.1 - 8.3e-06 25.4 2.7 0.16 11.9 0.1 5.4 4 0 0 4 4 4 2 Viral A-type inclusion protein repeat Aa_trans PF01490.18 PSC75656.1 - 1.2e-05 24.3 7.2 1.8e-05 23.7 7.2 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Hemagglutinin PF00509.18 PSC75656.1 - 9.4 4.5 6.2 6.4 5.0 0.7 2.2 2 0 0 2 2 2 0 Haemagglutinin Ank_2 PF12796.7 PSC75657.1 - 3.2e-22 78.9 0.1 7.8e-08 32.8 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC75657.1 - 6.4e-18 64.6 5.5 9e-08 32.3 0.1 5.5 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC75657.1 - 5.9e-16 58.6 0.5 2.1e-05 25.0 0.0 4.4 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC75657.1 - 1.2e-14 53.0 0.8 0.29 11.8 0.0 6.5 5 0 0 5 5 5 5 Ankyrin repeat Ank PF00023.30 PSC75657.1 - 5.4e-11 42.4 9.3 0.0025 18.2 0.0 6.0 5 0 0 5 5 5 3 Ankyrin repeat LRR_4 PF12799.7 PSC75657.1 - 0.24 11.9 0.0 14 6.3 0.0 3.1 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) P5CR_dimer PF14748.6 PSC75658.1 - 1.8e-41 140.6 2.4 1.8e-41 140.6 2.4 1.8 2 0 0 2 2 2 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 PSC75658.1 - 1.4e-12 48.0 0.0 4.4e-12 46.4 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent PDH PF02153.17 PSC75658.1 - 0.0046 16.0 0.0 0.0064 15.5 0.0 1.2 1 0 0 1 1 1 1 Prephenate dehydrogenase NAD_Gly3P_dh_N PF01210.23 PSC75658.1 - 0.041 13.8 0.0 0.071 13.1 0.0 1.3 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 PSC75658.1 - 0.052 13.2 0.0 0.093 12.4 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA zf-NF-X1 PF01422.17 PSC75659.1 - 0.00043 20.3 63.1 0.0044 17.0 15.1 17.9 20 1 0 20 20 20 9 NF-X1 type zinc finger Acetyltransf_10 PF13673.7 PSC75660.1 - 8.7e-05 22.5 0.0 0.00012 22.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PSC75660.1 - 0.0001 22.5 0.0 0.00014 22.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PSC75660.1 - 0.00025 21.4 0.0 0.00035 20.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC75660.1 - 0.00089 19.2 0.0 0.0015 18.4 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Btz PF09405.10 PSC75661.1 - 1.2e-07 32.0 19.9 1.3e-06 28.7 17.7 3.2 2 1 0 2 2 2 1 CASC3/Barentsz eIF4AIII binding Nop10p PF04135.12 PSC75662.1 - 5.5e-21 74.3 0.2 6.5e-21 74.1 0.2 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Cupin_3 PF05899.12 PSC75663.1 - 1.4e-30 104.8 0.4 2.6e-30 103.9 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 PSC75663.1 - 2.1e-07 30.5 0.0 5.3e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 PSC75663.1 - 0.00092 19.0 0.0 0.00092 19.0 0.0 2.3 2 2 0 2 2 2 1 Cupin EutQ PF06249.12 PSC75663.1 - 0.012 15.4 0.0 0.021 14.6 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Cupin_1 PF00190.22 PSC75663.1 - 0.048 13.3 0.0 0.085 12.5 0.0 1.4 1 0 0 1 1 1 0 Cupin TFIIA PF03153.13 PSC75663.1 - 4 7.3 18.7 4.8 7.1 18.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Cupin_3 PF05899.12 PSC75664.1 - 1.7e-30 104.5 0.4 3.2e-30 103.7 0.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF861) Cupin_2 PF07883.11 PSC75664.1 - 2.6e-07 30.3 0.0 6.4e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Cupin domain Cupin_6 PF12852.7 PSC75664.1 - 0.0014 18.4 0.0 0.0014 18.4 0.0 2.5 2 2 0 2 2 2 1 Cupin EutQ PF06249.12 PSC75664.1 - 0.014 15.2 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Ethanolamine utilisation protein EutQ Cupin_1 PF00190.22 PSC75664.1 - 0.056 13.1 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Cupin TFIIA PF03153.13 PSC75664.1 - 5.7 6.8 18.9 7.4 6.4 18.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit GUN4 PF05419.12 PSC75665.1 - 6e-49 165.7 0.3 7.7e-49 165.4 0.3 1.1 1 0 0 1 1 1 1 GUN4-like LTP_2 PF14368.6 PSC75666.1 - 0.084 13.0 5.3 0.12 12.5 3.6 2.2 2 1 0 2 2 2 0 Probable lipid transfer Ribosomal_S19e PF01090.19 PSC75668.1 - 2.5e-51 173.0 0.0 3e-51 172.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e HrcA_DNA-bdg PF03444.15 PSC75668.1 - 0.00022 20.8 0.0 0.00039 20.0 0.0 1.4 1 0 0 1 1 1 1 Winged helix-turn-helix transcription repressor, HrcA DNA-binding HTH_12 PF08461.10 PSC75668.1 - 0.025 14.5 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease R winged-helix domain TPR_1 PF00515.28 PSC75669.1 - 1.2e-24 85.1 3.1 3.8e-06 26.5 0.0 4.3 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 PSC75669.1 - 1.2e-21 75.0 12.2 3e-06 26.9 1.0 5.1 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 PSC75669.1 - 7.5e-18 63.9 6.1 1.3e-06 28.0 0.2 4.0 2 2 2 4 4 4 4 TPR repeat TPR_16 PF13432.6 PSC75669.1 - 1.8e-16 60.5 19.4 1.1e-08 35.5 7.0 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_9 PF13371.6 PSC75669.1 - 1.7e-14 53.7 12.0 0.00011 22.2 2.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 PSC75669.1 - 2.5e-13 49.1 0.8 0.018 15.2 0.1 4.6 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 PSC75669.1 - 6.1e-13 48.2 3.7 0.016 15.5 0.2 4.5 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.6 PSC75669.1 - 3.2e-12 45.6 2.3 0.0017 18.2 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 PSC75669.1 - 1.6e-11 44.6 8.6 5.2e-07 30.1 4.8 3.3 1 1 1 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 PSC75669.1 - 4.4e-11 42.9 9.8 2.7e-07 30.8 0.5 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 PSC75669.1 - 8.1e-11 41.8 23.5 5.6e-05 23.6 0.2 5.3 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_6 PF13174.6 PSC75669.1 - 3.3e-08 33.6 9.9 0.003 18.1 0.1 5.0 6 0 0 6 6 5 2 Tetratricopeptide repeat BTAD PF03704.17 PSC75669.1 - 1.1e-06 29.1 5.3 0.009 16.5 0.2 3.1 2 1 1 3 3 3 2 Bacterial transcriptional activator domain TPR_10 PF13374.6 PSC75669.1 - 1.5e-05 24.7 21.8 0.44 10.5 1.1 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat DUF3856 PF12968.7 PSC75669.1 - 0.032 14.3 0.1 2.1 8.4 0.0 2.8 1 1 0 2 2 2 0 Domain of Unknown Function (DUF3856) SHNi-TPR PF10516.9 PSC75669.1 - 0.061 12.8 0.0 17 5.0 0.0 3.3 3 0 0 3 3 3 0 SHNi-TPR Type_III_YscG PF09477.10 PSC75669.1 - 0.075 13.1 0.7 0.17 11.9 0.4 1.8 1 1 0 1 1 1 0 Bacterial type II secretion system chaperone protein (type_III_yscG) TPR_4 PF07721.14 PSC75669.1 - 0.1 13.2 36.2 3.7 8.5 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat NARP1 PF12569.8 PSC75669.1 - 0.17 10.8 0.0 1.9 7.3 0.0 1.8 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 EamA PF00892.20 PSC75670.1 - 3e-12 46.9 25.9 5.5e-07 29.8 11.7 2.5 3 0 0 3 3 3 2 EamA-like transporter family DUF4235 PF14019.6 PSC75671.1 - 0.49 10.5 2.3 1.1 9.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4235) ADH_zinc_N PF00107.26 PSC75672.1 - 2.6e-25 88.9 0.3 5.3e-25 87.9 0.3 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PSC75672.1 - 7.3e-25 87.0 0.1 2.5e-24 85.3 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 PSC75672.1 - 3.9e-06 28.0 0.0 1.1e-05 26.5 0.0 1.9 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Glu_dehyd_C PF16912.5 PSC75672.1 - 4.4e-06 26.3 1.2 8.8e-06 25.4 1.2 1.4 1 0 0 1 1 1 1 Glucose dehydrogenase C-terminus AlaDh_PNT_C PF01262.21 PSC75672.1 - 0.0025 17.2 2.8 0.0051 16.1 2.8 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain 2-Hacid_dh_C PF02826.19 PSC75672.1 - 0.013 14.9 0.1 0.025 13.9 0.1 1.6 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Methyltransf_25 PF13649.6 PSC75672.1 - 0.027 15.2 1.0 0.064 14.0 0.1 2.1 2 0 0 2 2 2 0 Methyltransferase domain UDPG_MGDP_dh_N PF03721.14 PSC75672.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain HTH_20 PF12840.7 PSC75673.1 - 0.012 15.7 5.3 0.024 14.7 2.2 3.4 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_20 PF12840.7 PSC75674.1 - 0.012 15.7 5.3 0.024 14.7 2.2 3.4 2 0 0 2 2 2 0 Helix-turn-helix domain DHO_dh PF01180.21 PSC75675.1 - 2.8e-99 332.1 0.0 4.1e-99 331.5 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ATG16 PF08614.11 PSC75675.1 - 1.4 9.1 7.9 3.3 7.9 7.9 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DHO_dh PF01180.21 PSC75676.1 - 2.8e-99 332.1 0.0 4.1e-99 331.5 0.0 1.3 1 0 0 1 1 1 1 Dihydroorotate dehydrogenase ATG16 PF08614.11 PSC75676.1 - 1.4 9.1 7.9 3.3 7.9 7.9 1.5 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) RNA_pol_Rpb4 PF03874.16 PSC75678.1 - 4.7e-15 56.0 0.4 1.2e-14 54.7 0.4 1.6 1 1 0 1 1 1 1 RNA polymerase Rpb4 Chloroplast_duf PF14476.6 PSC75679.1 - 6.6 5.6 7.2 14 4.5 7.2 1.5 1 0 0 1 1 1 0 Petal formation-expressed Cpn60_TCP1 PF00118.24 PSC75680.1 - 2.1e-153 511.5 8.0 2.3e-153 511.4 8.0 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nucleoside_tran PF01733.18 PSC75682.1 - 5.8e-43 147.4 4.3 4.2e-27 95.4 3.1 2.6 2 1 0 2 2 2 2 Nucleoside transporter SNARE_assoc PF09335.11 PSC75683.1 - 2.9e-26 92.3 8.8 2.9e-26 92.3 8.8 2.4 3 0 0 3 3 3 1 SNARE associated Golgi protein Methyltransf_5 PF01795.19 PSC75684.1 - 4.7e-91 305.5 0.0 8.1e-90 301.5 0.0 2.1 1 1 0 1 1 1 1 MraW methylase family Methyltransf_2 PF00891.18 PSC75684.1 - 0.11 11.7 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain LRR_8 PF13855.6 PSC75685.1 - 4.8e-20 71.1 11.3 1.7e-08 34.1 0.2 3.5 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 PSC75685.1 - 2.3e-18 66.0 2.3 0.0021 18.4 2.5 5.0 3 1 2 5 5 5 5 Leucine Rich repeats (2 copies) DUF563 PF04577.14 PSC75685.1 - 4.2e-10 40.1 0.0 2.2e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF563) LRR_9 PF14580.6 PSC75685.1 - 3e-05 23.6 1.8 0.056 12.9 0.2 2.3 1 1 0 2 2 2 2 Leucine-rich repeat ubiquitin PF00240.23 PSC75685.1 - 0.00013 21.7 0.0 0.00029 20.5 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family LRR_6 PF13516.6 PSC75685.1 - 0.021 14.9 3.5 14 6.1 0.0 5.1 5 0 0 5 5 5 0 Leucine Rich repeat Serglycin PF04360.12 PSC75685.1 - 0.59 10.1 6.9 1.6 8.6 4.8 2.2 2 0 0 2 2 2 0 Serglycin AF-4 PF05110.13 PSC75685.1 - 8.1 4.4 4.7 12 3.8 4.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein LRR_8 PF13855.6 PSC75686.1 - 4e-20 71.3 11.3 1.6e-08 34.1 0.2 3.6 3 0 0 3 3 3 3 Leucine rich repeat LRR_4 PF12799.7 PSC75686.1 - 2.5e-17 62.7 5.9 0.002 18.5 2.5 5.0 4 1 2 6 6 6 5 Leucine Rich repeats (2 copies) DUF563 PF04577.14 PSC75686.1 - 3.8e-10 40.3 0.0 2.1e-09 37.9 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF563) LRR_9 PF14580.6 PSC75686.1 - 2.6e-05 23.8 1.8 0.053 13.0 0.2 2.3 1 1 0 2 2 2 2 Leucine-rich repeat ubiquitin PF00240.23 PSC75686.1 - 0.00012 21.7 0.0 0.00027 20.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family LRR_6 PF13516.6 PSC75686.1 - 0.017 15.2 3.5 13 6.1 0.0 5.1 5 0 0 5 5 5 0 Leucine Rich repeat Serglycin PF04360.12 PSC75686.1 - 1.2 9.0 5.4 2.3 8.1 5.4 1.4 1 0 0 1 1 1 0 Serglycin AF-4 PF05110.13 PSC75686.1 - 7.8 4.4 4.7 11 3.9 4.7 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein PP2C PF00481.21 PSC75687.1 - 3.4e-52 177.7 0.0 6.2e-52 176.8 0.0 1.4 1 1 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PSC75687.1 - 2.8e-05 23.9 0.5 7.2e-05 22.5 0.5 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C AAA_34 PF13872.6 PSC75688.1 - 2.1e-123 411.0 0.0 3.5e-123 410.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 PSC75688.1 - 2e-105 352.4 0.8 3.5e-105 351.6 0.0 1.9 2 0 0 2 2 2 1 C-terminal domain on Strawberry notch homologue EVE PF01878.18 PSC75688.1 - 2.6e-08 34.0 0.0 5.8e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 EVE domain ResIII PF04851.15 PSC75688.1 - 0.0063 16.5 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_34 PF13872.6 PSC75689.1 - 2.2e-123 411.0 0.0 3.5e-123 410.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 Helicase_C_4 PF13871.6 PSC75689.1 - 2e-105 352.3 0.8 3.5e-105 351.6 0.0 1.9 2 0 0 2 2 2 1 C-terminal domain on Strawberry notch homologue EVE PF01878.18 PSC75689.1 - 2.6e-08 34.0 0.0 5.8e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 EVE domain ResIII PF04851.15 PSC75689.1 - 0.0063 16.5 0.0 0.018 15.1 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Trypsin PF00089.26 PSC75690.1 - 2.8e-48 164.7 0.0 3.8e-48 164.2 0.0 1.2 1 0 0 1 1 1 1 Trypsin Trypsin_2 PF13365.6 PSC75690.1 - 2.4e-08 35.0 1.1 3.8e-08 34.4 0.0 1.7 2 0 0 2 2 2 1 Trypsin-like peptidase domain K_channel_TID PF07941.11 PSC75690.1 - 0.13 12.7 5.8 0.41 11.1 5.8 1.9 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain RVT_2 PF07727.14 PSC75691.1 - 2.9e-71 239.9 0.0 4e-71 239.5 0.0 1.2 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PSC75691.1 - 8.3e-24 84.1 0.0 9.6e-23 80.6 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain gag_pre-integrs PF13976.6 PSC75691.1 - 5.1e-10 39.1 0.0 1.3e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 PSC75691.1 - 7.9e-06 25.6 0.0 9.3e-05 22.1 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain RVT_2 PF07727.14 PSC75692.1 - 2.8e-71 240.0 0.0 4.5e-71 239.3 0.0 1.3 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.26 PSC75692.1 - 1.1e-23 83.7 0.0 1.1e-22 80.5 0.0 2.4 2 0 0 2 2 2 1 Integrase core domain Retrotran_gag_2 PF14223.6 PSC75692.1 - 5.3e-22 78.0 0.0 9.1e-22 77.2 0.0 1.3 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type gag_pre-integrs PF13976.6 PSC75692.1 - 7.4e-10 38.5 0.0 1.4e-09 37.6 0.0 1.5 1 0 0 1 1 1 1 GAG-pre-integrase domain rve_3 PF13683.6 PSC75692.1 - 8.9e-06 25.4 0.0 0.0001 22.0 0.0 2.5 2 0 0 2 2 2 1 Integrase core domain MBD PF01429.19 PSC75693.1 - 1.7e-19 69.2 0.0 8.2e-09 35.1 0.0 2.5 2 0 0 2 2 2 2 Methyl-CpG binding domain PHD PF00628.29 PSC75693.1 - 2.2e-11 43.4 5.1 2.2e-11 43.4 5.1 2.7 2 0 0 2 2 2 1 PHD-finger SNase PF00565.17 PSC75693.1 - 0.42 11.1 3.5 1.1 9.8 3.5 1.6 1 0 0 1 1 1 0 Staphylococcal nuclease homologue Kinesin PF00225.23 PSC75696.1 - 1.2e-37 129.7 0.0 2.2e-37 128.7 0.0 1.3 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PSC75696.1 - 2e-07 31.0 0.0 4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding ATP-grasp PF02222.22 PSC75696.1 - 0.13 11.8 0.1 0.34 10.5 0.1 1.6 1 0 0 1 1 1 0 ATP-grasp domain Lzipper-MIP1 PF14389.6 PSC75696.1 - 0.79 10.1 7.8 16 5.9 0.2 2.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Leu_zip PF15294.6 PSC75696.1 - 1 8.8 6.4 6.7 6.1 0.6 2.4 2 0 0 2 2 2 0 Leucine zipper rve PF00665.26 PSC75697.1 - 1.3e-18 67.3 0.0 2.6e-18 66.3 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC75697.1 - 0.0098 15.7 0.0 0.026 14.3 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain CAP_N PF01213.19 PSC75697.1 - 0.2 11.1 1.7 0.47 9.9 1.7 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 PSC75697.1 - 6.1 6.9 6.5 19 5.3 6.5 1.8 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 rve PF00665.26 PSC75698.1 - 1.2e-18 67.4 0.0 2.4e-18 66.4 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC75698.1 - 0.0093 15.7 0.0 0.024 14.4 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain CAP_N PF01213.19 PSC75698.1 - 0.047 13.2 3.3 0.11 11.9 3.3 1.6 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal zf-MYND PF01753.18 PSC75699.1 - 2.3e-10 40.4 0.9 2.3e-10 40.4 0.9 3.8 4 0 0 4 4 4 1 MYND finger TPR_2 PF07719.17 PSC75699.1 - 7.9e-06 25.6 4.5 7.2e-05 22.6 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Ank_3 PF13606.6 PSC75699.1 - 0.00041 20.6 0.3 0.5 11.1 0.0 3.8 3 1 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 PSC75699.1 - 0.0012 19.4 0.0 0.016 15.8 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC75699.1 - 0.0014 19.1 0.1 0.0058 17.2 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) TPR_1 PF00515.28 PSC75699.1 - 0.0021 17.8 0.5 0.0065 16.2 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 PSC75699.1 - 0.0025 17.7 0.5 0.048 13.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 PSC75699.1 - 0.0032 17.1 0.1 0.007 16.0 0.1 1.6 1 0 0 1 1 1 1 TPR repeat Ank_5 PF13857.6 PSC75699.1 - 0.012 15.9 0.1 0.054 13.8 0.0 2.1 2 0 0 2 2 2 0 Ankyrin repeats (many copies) TPR_12 PF13424.6 PSC75699.1 - 0.019 15.3 0.8 0.051 13.9 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 PSC75699.1 - 0.14 12.8 1.4 0.32 11.7 0.1 2.3 2 0 0 2 2 1 0 Tetratricopeptide repeat zf-MYND PF01753.18 PSC75700.1 - 2.4e-10 40.3 0.9 2.4e-10 40.3 0.9 3.7 4 0 0 4 4 4 1 MYND finger TPR_2 PF07719.17 PSC75700.1 - 9.1e-06 25.4 4.5 7.5e-05 22.5 0.0 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat Ank_3 PF13606.6 PSC75700.1 - 0.00043 20.5 0.3 0.53 11.0 0.0 3.9 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.7 PSC75700.1 - 0.0012 19.4 0.0 0.018 15.7 0.0 2.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC75700.1 - 0.0015 19.1 0.1 0.0061 17.1 0.1 2.2 1 1 1 2 2 2 1 Ankyrin repeats (many copies) TPR_1 PF00515.28 PSC75700.1 - 0.0023 17.7 0.5 0.0068 16.2 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 PSC75700.1 - 0.0028 17.6 0.5 0.051 13.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 PSC75700.1 - 0.0034 17.0 0.1 0.0073 16.0 0.1 1.6 1 0 0 1 1 1 1 TPR repeat Ank_5 PF13857.6 PSC75700.1 - 0.012 15.9 0.1 0.057 13.8 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeats (many copies) TPR_12 PF13424.6 PSC75700.1 - 0.02 15.1 0.8 0.054 13.8 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 PSC75700.1 - 0.15 12.7 1.4 0.34 11.7 0.1 2.3 2 0 0 2 2 1 0 Tetratricopeptide repeat Cas1_AcylT PF07779.12 PSC75701.1 - 5.4e-90 302.6 15.6 8.2e-90 302.0 15.6 1.2 1 1 0 1 1 1 1 10 TM Acyl Transferase domain found in Cas1p DUF3042 PF11240.8 PSC75701.1 - 9.2 6.4 7.7 6.1 6.9 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) mTERF PF02536.14 PSC75702.1 - 0.0033 16.4 0.0 0.0048 15.9 0.0 1.1 1 0 0 1 1 1 1 mTERF IBR PF01485.21 PSC75702.1 - 0.056 13.7 0.0 0.16 12.2 0.0 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DZR PF12773.7 PSC75702.1 - 0.34 11.0 3.2 0.83 9.7 0.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-C2HC_2 PF13913.6 PSC75702.1 - 0.58 10.1 11.4 0.3 11.0 0.2 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type TFIIA PF03153.13 PSC75702.1 - 2.3 8.1 22.9 0.33 10.9 6.5 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zinc_ribbon_2 PF13240.6 PSC75702.1 - 2.8 7.8 6.6 0.37 10.6 0.6 2.4 2 0 0 2 2 2 0 zinc-ribbon domain mTERF PF02536.14 PSC75703.1 - 0.0033 16.4 0.0 0.0048 15.9 0.0 1.1 1 0 0 1 1 1 1 mTERF IBR PF01485.21 PSC75703.1 - 0.056 13.7 0.0 0.16 12.2 0.0 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DZR PF12773.7 PSC75703.1 - 0.34 11.0 3.2 0.83 9.7 0.2 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-C2HC_2 PF13913.6 PSC75703.1 - 0.58 10.1 11.4 0.3 11.0 0.2 3.3 3 0 0 3 3 3 0 zinc-finger of a C2HC-type TFIIA PF03153.13 PSC75703.1 - 2.7 7.9 24.0 0.34 10.9 6.5 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit zinc_ribbon_2 PF13240.6 PSC75703.1 - 2.8 7.8 6.6 0.37 10.6 0.6 2.4 2 0 0 2 2 2 0 zinc-ribbon domain RIB43A PF05914.12 PSC75704.1 - 9.7e-34 116.7 19.4 7e-22 77.7 13.5 2.0 1 1 1 2 2 2 2 RIB43A Dehydrin PF00257.19 PSC75704.1 - 4.2 7.9 7.1 10 6.6 0.2 2.2 2 0 0 2 2 2 0 Dehydrin DUF572 PF04502.13 PSC75704.1 - 5.1 6.6 8.6 7.4 6.1 8.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) Dehydrin PF00257.19 PSC75705.1 - 1.5 9.4 8.6 0.45 11.1 2.7 2.4 2 0 0 2 2 2 0 Dehydrin Mpv17_PMP22 PF04117.12 PSC75706.1 - 7.9e-19 67.7 0.7 1.3e-18 67.0 0.7 1.3 1 0 0 1 1 1 1 Mpv17 / PMP22 family G-patch PF01585.23 PSC75708.1 - 1.8e-12 47.0 1.0 4.7e-12 45.6 1.0 1.8 1 0 0 1 1 1 1 G-patch domain Totivirus_coat PF05518.11 PSC75708.1 - 0.059 11.4 6.5 0.078 11.0 6.5 1.2 1 0 0 1 1 1 0 Totivirus coat protein Imm49 PF15575.6 PSC75708.1 - 0.21 11.4 4.6 0.41 10.4 4.6 1.4 1 0 0 1 1 1 0 Immunity protein 49 zf-met PF12874.7 PSC75708.1 - 0.25 11.8 3.1 0.38 11.2 3.1 1.3 1 0 0 1 1 1 0 Zinc-finger of C2H2 type DUF4778 PF16008.5 PSC75708.1 - 0.39 10.7 7.5 0.6 10.1 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) DUF4554 PF15091.6 PSC75708.1 - 0.44 9.4 3.9 0.61 8.9 3.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4554) UPF0054 PF02130.17 PSC75708.1 - 0.49 10.2 3.2 0.9 9.3 3.2 1.4 1 0 0 1 1 1 0 Uncharacterized protein family UPF0054 zf-C2H2_jaz PF12171.8 PSC75708.1 - 0.54 10.6 5.8 0.91 9.9 5.8 1.3 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding zf-DBF PF07535.12 PSC75708.1 - 2.2 8.5 9.6 4.1 7.6 9.6 1.3 1 0 0 1 1 1 0 DBF zinc finger TFIIS_M PF07500.14 PSC75709.1 - 1.7e-25 89.7 0.0 2.7e-25 89.0 0.0 1.3 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 PSC75709.1 - 1.6e-19 69.5 7.4 3e-19 68.6 7.4 1.5 1 0 0 1 1 1 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 PSC75709.1 - 2.7e-07 30.5 0.2 5.4e-07 29.5 0.2 1.6 1 0 0 1 1 1 1 TFIIS helical bundle-like domain zf-DNL PF05180.12 PSC75709.1 - 0.27 11.2 1.7 0.54 10.2 1.7 1.4 1 0 0 1 1 1 0 DNL zinc finger Elf1 PF05129.13 PSC75709.1 - 0.3 11.1 3.5 0.67 10.0 3.5 1.6 1 0 0 1 1 1 0 Transcription elongation factor Elf1 like MutS_I PF01624.20 PSC75710.1 - 5.9e-12 45.8 0.0 1.2e-11 44.9 0.0 1.5 1 0 0 1 1 1 1 MutS domain I RPAP1_N PF08621.10 PSC75711.1 - 5.2e-14 51.7 0.5 1.1e-13 50.7 0.5 1.6 1 0 0 1 1 1 1 RPAP1-like, N-terminal RPAP1_C PF08620.10 PSC75711.1 - 2.6e-10 40.3 0.0 8.4e-10 38.6 0.0 2.0 1 0 0 1 1 1 1 RPAP1-like, C-terminal Tweety PF04906.13 PSC75711.1 - 0.0042 15.8 0.6 0.0082 14.9 0.6 1.4 1 0 0 1 1 1 1 Tweety TANGO2 PF05742.12 PSC75712.1 - 4.9e-51 174.2 0.0 1.9e-50 172.3 0.0 1.8 1 1 0 1 1 1 1 Transport and Golgi organisation 2 Asparaginase_2 PF01112.18 PSC75713.1 - 4e-39 134.5 20.9 1.2e-36 126.3 13.3 3.1 2 1 0 2 2 2 2 Asparaginase Oxidored_q2 PF00420.24 PSC75714.1 - 0.14 11.8 0.6 0.69 9.6 0.1 2.2 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L DUF3301 PF11743.8 PSC75714.1 - 1.4 8.7 7.0 15 5.3 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3301) FAD_binding_2 PF00890.24 PSC75715.1 - 1.1e-57 196.0 4.5 1.1e-57 196.0 4.5 1.7 2 0 0 2 2 2 1 FAD binding domain adh_short PF00106.25 PSC75715.1 - 9.2e-36 123.1 0.6 2e-35 122.0 0.6 1.5 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC75715.1 - 1.3e-25 90.4 0.2 2.9e-25 89.2 0.2 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC75715.1 - 1.6e-09 37.9 1.0 3.9e-09 36.7 0.2 1.9 2 0 0 2 2 2 1 KR domain NAD_binding_10 PF13460.6 PSC75715.1 - 5.2e-06 26.5 1.9 1.5e-05 25.0 0.6 2.6 3 1 0 3 3 3 1 NAD(P)H-binding Epimerase PF01370.21 PSC75715.1 - 9.7e-05 21.9 0.1 0.00019 21.0 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DprA_WH PF17782.1 PSC75715.1 - 0.018 15.1 1.3 0.018 15.1 1.3 2.3 2 0 0 2 2 2 0 DprA winged helix domain NmrA PF05368.13 PSC75715.1 - 0.022 14.3 0.4 0.037 13.6 0.4 1.3 1 0 0 1 1 1 0 NmrA-like family RmlD_sub_bind PF04321.17 PSC75715.1 - 0.038 13.1 0.1 0.069 12.2 0.1 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain 2-Hacid_dh_C PF02826.19 PSC75715.1 - 0.079 12.3 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pkinase PF00069.25 PSC75716.1 - 5.8e-39 134.0 0.0 1.8e-38 132.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC75716.1 - 8.9e-38 130.0 0.0 6.9e-37 127.1 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PSC75716.1 - 0.048 13.0 0.1 0.086 12.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Herpes_gE PF02480.16 PSC75716.1 - 0.054 12.2 0.1 0.088 11.5 0.1 1.2 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Pkinase_fungal PF17667.1 PSC75716.1 - 0.17 10.7 0.0 0.25 10.1 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase 5TM-5TMR_LYT PF07694.12 PSC75716.1 - 1.9 8.0 5.3 5.3 6.5 0.1 2.2 2 0 0 2 2 2 0 5TMR of 5TMR-LYT Roughex PF06020.11 PSC75717.1 - 0.09 11.9 0.1 0.19 10.8 0.1 1.4 1 0 0 1 1 1 0 Drosophila roughex protein B3 PF02362.21 PSC75717.1 - 0.14 12.0 0.0 11 5.9 0.0 3.0 3 0 0 3 3 3 0 B3 DNA binding domain CDC48_N PF02359.18 PSC75717.1 - 0.22 11.7 0.0 1.7 8.8 0.0 2.3 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain Myosin_head PF00063.21 PSC75718.1 - 2e-241 802.9 0.0 2.8e-241 802.5 0.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 PSC75718.1 - 2.1e-23 82.6 1.3 2.1e-23 82.6 1.3 2.6 3 0 0 3 3 3 1 DIL domain IQ PF00612.27 PSC75718.1 - 2.3e-20 70.4 49.8 6.1e-06 25.6 0.4 6.9 6 0 0 6 6 6 6 IQ calmodulin-binding motif DUF4539 PF15072.6 PSC75718.1 - 6e-12 45.4 0.0 1.2e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) Hpr_kinase_C PF07475.12 PSC75718.1 - 0.038 13.5 0.2 4.2 6.9 0.0 2.6 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 PSC75718.1 - 0.39 11.1 0.0 0.39 11.1 0.0 4.4 3 1 0 3 3 3 0 AAA ATPase domain AAA_22 PF13401.6 PSC75718.1 - 0.45 10.8 2.8 0.85 9.9 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF1515 PF07439.11 PSC75718.1 - 1.2 9.1 11.2 0.083 12.9 1.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) AAA_18 PF13238.6 PSC75718.1 - 1.8 9.1 4.5 5 7.7 0.0 3.2 3 1 0 3 3 3 0 AAA domain AP2 PF00847.20 PSC75719.1 - 3e-17 62.6 2.1 1.9e-08 34.4 0.5 2.4 2 0 0 2 2 2 2 AP2 domain FliG_M PF14841.6 PSC75720.1 - 0.12 12.6 0.1 0.3 11.3 0.1 1.6 1 0 0 1 1 1 0 FliG middle domain ORMDL PF04061.14 PSC75721.1 - 6e-44 149.2 1.8 1e-43 148.4 1.8 1.3 1 0 0 1 1 1 1 ORMDL family Peptidase_S10 PF00450.22 PSC75722.1 - 4.6e-61 207.5 0.0 1.1e-36 127.2 0.0 2.0 1 1 1 2 2 2 2 Serine carboxypeptidase Aminotran_3 PF00202.21 PSC75723.1 - 2.5e-113 378.8 0.1 3.5e-113 378.3 0.1 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Fra10Ac1 PF09725.9 PSC75724.1 - 1.1e-46 158.0 0.3 1.9e-46 157.2 0.3 1.4 1 0 0 1 1 1 1 Folate-sensitive fragile site protein Fra10Ac1 DUF3287 PF11690.8 PSC75725.1 - 0.4 10.4 5.1 1.1 9.0 0.2 4.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) adh_short PF00106.25 PSC75726.1 - 1.4e-18 67.0 0.0 2.1e-12 46.9 0.0 2.3 1 1 1 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PSC75726.1 - 1.6e-10 41.0 0.0 1.1e-08 35.0 0.0 2.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase bPH_2 PF03703.14 PSC75726.1 - 3.4e-08 33.5 0.1 7.5e-08 32.5 0.1 1.6 1 0 0 1 1 1 1 Bacterial PH domain IMUP PF15761.5 PSC75726.1 - 0.13 13.0 2.3 0.3 11.8 2.3 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein bPH_3 PF14470.6 PSC75726.1 - 0.2 12.1 0.0 0.36 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial PH domain SR-25 PF10500.9 PSC75726.1 - 0.2 11.2 1.7 0.37 10.4 1.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF1421 PF07223.11 PSC75727.1 - 1.7e-10 40.6 0.6 3.1e-10 39.7 0.6 1.4 1 0 0 1 1 1 1 UBA-like domain (DUF1421) CorA PF01544.18 PSC75727.1 - 0.0034 16.7 0.2 0.0051 16.2 0.2 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein Spc7 PF08317.11 PSC75727.1 - 0.094 11.6 0.6 0.14 11.0 0.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein FKBP_C PF00254.28 PSC75728.1 - 1.2e-13 51.2 0.0 2.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase AAA PF00004.29 PSC75729.1 - 1.1e-28 100.2 0.0 1.6e-28 99.8 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PSC75729.1 - 1.6e-07 31.9 0.1 3.8e-07 30.6 0.1 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 PSC75729.1 - 1.8e-07 31.5 0.2 1.4e-06 28.6 0.2 2.3 2 1 0 2 2 1 1 AAA domain AAA_18 PF13238.6 PSC75729.1 - 3.9e-05 24.2 0.0 9.1e-05 23.0 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_25 PF13481.6 PSC75729.1 - 0.0001 21.9 1.0 0.049 13.2 0.0 2.5 1 1 0 2 2 2 1 AAA domain AAA_33 PF13671.6 PSC75729.1 - 0.00019 21.6 0.0 0.00032 20.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PSC75729.1 - 0.00023 21.0 0.1 0.0087 15.8 0.0 2.5 2 1 0 2 2 2 1 AAA domain NACHT PF05729.12 PSC75729.1 - 0.00047 20.1 0.2 0.0043 17.0 0.2 2.2 1 1 0 1 1 1 1 NACHT domain RuvB_N PF05496.12 PSC75729.1 - 0.00075 19.3 0.0 0.0016 18.2 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_14 PF13173.6 PSC75729.1 - 0.0014 18.6 0.0 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 PSC75729.1 - 0.0015 18.9 0.0 0.0028 18.0 0.0 1.5 1 0 0 1 1 1 1 RNA helicase AAA_5 PF07728.14 PSC75729.1 - 0.0018 18.3 0.1 0.0039 17.2 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 PSC75729.1 - 0.0019 18.5 0.0 0.0043 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 PSC75729.1 - 0.0032 17.5 0.0 0.0069 16.4 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 PSC75729.1 - 0.0041 17.0 0.0 0.0068 16.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 PSC75729.1 - 0.005 17.0 0.0 0.0074 16.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Cytidylate_kin PF02224.18 PSC75729.1 - 0.0073 16.1 0.1 0.017 14.9 0.1 1.7 1 1 0 1 1 1 1 Cytidylate kinase Viral_helicase1 PF01443.18 PSC75729.1 - 0.0082 15.9 0.0 0.013 15.3 0.0 1.2 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 PSC75729.1 - 0.0084 15.9 0.0 0.023 14.4 0.0 1.7 2 0 0 2 2 1 1 IstB-like ATP binding protein KAP_NTPase PF07693.14 PSC75729.1 - 0.013 14.8 0.0 0.94 8.6 0.0 2.1 1 1 1 2 2 2 0 KAP family P-loop domain AAA_7 PF12775.7 PSC75729.1 - 0.013 15.0 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region PduV-EutP PF10662.9 PSC75729.1 - 0.017 14.9 0.0 0.032 14.0 0.0 1.4 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_24 PF13479.6 PSC75729.1 - 0.021 14.5 0.0 0.042 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain Rad17 PF03215.15 PSC75729.1 - 0.022 14.7 0.2 0.064 13.2 0.0 1.7 2 1 0 2 2 1 0 Rad17 P-loop domain FtsK_SpoIIIE PF01580.18 PSC75729.1 - 0.023 14.1 0.1 0.92 8.8 0.1 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family TIP49 PF06068.13 PSC75729.1 - 0.026 13.7 0.0 0.037 13.2 0.0 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_19 PF13245.6 PSC75729.1 - 0.029 14.7 0.5 0.17 12.2 0.1 2.3 2 1 1 3 3 3 0 AAA domain ATPase PF06745.13 PSC75729.1 - 0.033 13.5 0.1 0.72 9.1 0.0 2.1 1 1 1 2 2 2 0 KaiC Mg_chelatase PF01078.21 PSC75729.1 - 0.043 13.2 0.0 0.097 12.0 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.9 PSC75729.1 - 0.065 12.5 0.0 0.087 12.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) WPP PF13943.6 PSC75729.1 - 0.072 13.5 0.0 0.18 12.2 0.0 1.6 1 0 0 1 1 1 0 WPP domain ATPase_2 PF01637.18 PSC75729.1 - 0.084 12.8 0.1 12 5.7 0.0 2.2 1 1 1 2 2 2 0 ATPase domain predominantly from Archaea AAA_17 PF13207.6 PSC75729.1 - 0.085 13.3 0.0 0.19 12.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 PSC75729.1 - 0.088 12.0 0.1 0.25 10.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 PSC75729.1 - 0.093 13.2 0.0 0.17 12.4 0.0 1.4 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.16 PSC75729.1 - 0.099 12.1 0.0 0.23 10.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein CPT PF07931.12 PSC75729.1 - 0.1 12.4 0.0 0.27 11.1 0.0 1.8 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_13 PF13166.6 PSC75729.1 - 0.12 11.0 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 PSC75729.1 - 0.15 11.9 0.0 0.35 10.7 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 PSC75729.1 - 0.18 11.7 0.2 0.38 10.6 0.0 1.6 2 0 0 2 2 1 0 NTPase zf-MYND PF01753.18 PSC75730.1 - 7.3e-07 29.2 16.4 1.4e-06 28.2 16.4 1.6 1 0 0 1 1 1 1 MYND finger UFC1 PF08694.11 PSC75731.1 - 6.5e-81 269.4 0.2 9.4e-81 268.9 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 adh_short PF00106.25 PSC75731.1 - 6.8e-25 87.7 0.0 1.8e-24 86.3 0.0 1.6 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC75731.1 - 5.6e-20 71.9 0.0 1.2e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase UQ_con PF00179.26 PSC75731.1 - 0.0084 15.8 0.1 0.017 14.8 0.1 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Flg_hook PF02120.16 PSC75731.1 - 0.082 12.8 0.3 2.4 8.1 0.0 2.7 3 0 0 3 3 3 0 Flagellar hook-length control protein FliK RWD PF05773.22 PSC75731.1 - 0.14 12.4 0.0 0.32 11.3 0.0 1.6 2 0 0 2 2 2 0 RWD domain DEAD PF00270.29 PSC75732.1 - 1.3e-33 116.3 0.0 2.2e-33 115.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC75732.1 - 1.6e-25 89.6 0.1 2.8e-25 88.8 0.1 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ERCC3_RAD25_C PF16203.5 PSC75732.1 - 0.00093 18.5 0.0 0.0014 17.8 0.0 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase ResIII PF04851.15 PSC75732.1 - 0.017 15.1 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit DUF1028 PF06267.12 PSC75732.1 - 2 8.1 31.4 0.043 13.6 19.3 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF1028) Galactosyl_T PF01762.21 PSC75735.1 - 2.4e-26 92.7 0.0 3.5e-26 92.3 0.0 1.1 1 0 0 1 1 1 1 Galactosyltransferase Fringe PF02434.16 PSC75735.1 - 0.13 11.7 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Fringe-like CmcI PF04989.12 PSC75735.1 - 0.17 11.6 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase SPX PF03105.19 PSC75736.1 - 1.1e-05 25.6 5.8 0.00035 20.6 0.0 2.8 2 1 1 3 3 3 2 SPX domain DUF2722 PF10846.8 PSC75736.1 - 0.0098 14.9 0.9 0.013 14.4 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF5639 PF18690.1 PSC75736.1 - 0.11 12.7 2.5 2.6 8.3 1.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5639) Spt20 PF12090.8 PSC75736.1 - 0.22 11.1 7.2 0.36 10.4 7.2 1.3 1 0 0 1 1 1 0 Spt20 family MTP18 PF10558.9 PSC75737.1 - 5.4e-16 59.0 0.0 8e-16 58.5 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial 18 KDa protein (MTP18) COG2 PF06148.11 PSC75738.1 - 1.1e-35 122.7 0.0 3e-35 121.2 0.0 1.8 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 PSC75738.1 - 1e-31 109.9 0.0 4e-31 108.0 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF3510) Vps51 PF08700.11 PSC75738.1 - 2.4e-05 24.3 0.2 0.0039 17.2 0.0 2.7 2 0 0 2 2 2 1 Vps51/Vps67 Sec8_exocyst PF04048.14 PSC75738.1 - 0.0015 18.5 0.1 0.0028 17.6 0.1 1.4 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Spc7 PF08317.11 PSC75738.1 - 0.045 12.6 0.1 0.086 11.7 0.1 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2274 PF10038.9 PSC75738.1 - 0.075 13.5 1.4 0.26 11.7 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2274) CAP_N PF01213.19 PSC75738.1 - 0.098 12.1 0.1 0.3 10.5 0.1 1.9 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SNARE_assoc PF09335.11 PSC75739.1 - 5.1e-26 91.5 10.2 5.1e-26 91.5 10.2 2.3 2 0 0 2 2 2 1 SNARE associated Golgi protein Xan_ur_permease PF00860.20 PSC75740.1 - 4.2e-26 91.5 35.7 2.2e-16 59.5 17.8 2.2 2 0 0 2 2 2 2 Permease family DUF5464 PF17552.2 PSC75740.1 - 0.0018 18.5 0.6 0.0054 17.0 0.2 2.1 2 0 0 2 2 2 1 Family of unknown function (DUF5464) AlaDh_PNT_C PF01262.21 PSC75741.1 - 3e-37 128.0 5.1 3e-37 128.0 5.1 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 PSC75741.1 - 1.6e-36 125.6 0.7 6.4e-36 123.7 0.1 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, N-terminal domain ADH_zinc_N PF00107.26 PSC75741.1 - 0.003 17.5 2.3 0.015 15.3 0.7 2.8 3 0 0 3 3 3 1 Zinc-binding dehydrogenase HI0933_like PF03486.14 PSC75741.1 - 0.066 11.9 2.3 0.11 11.1 2.3 1.3 1 0 0 1 1 1 0 HI0933-like protein 2-Hacid_dh_C PF02826.19 PSC75741.1 - 0.076 12.4 1.2 2.9 7.2 0.4 3.0 1 1 2 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain BPL_LplA_LipB PF03099.19 PSC75742.1 - 4.9e-09 36.2 0.0 7.3e-09 35.6 0.0 1.2 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family NTPase_1 PF03266.15 PSC75743.1 - 8.4e-06 25.8 0.1 0.074 13.0 0.0 2.3 2 0 0 2 2 2 2 NTPase AAA PF00004.29 PSC75743.1 - 1.6e-05 25.3 0.0 2.7e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 PSC75743.1 - 2.4e-05 24.1 0.1 9.5e-05 22.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 PSC75743.1 - 0.00031 21.3 0.0 0.00057 20.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PSC75743.1 - 0.00072 19.8 0.1 0.0025 18.1 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 PSC75743.1 - 0.0014 18.6 0.0 0.0036 17.3 0.0 1.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PSC75743.1 - 0.0019 18.6 0.0 0.0019 18.6 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_24 PF13479.6 PSC75743.1 - 0.0026 17.5 0.0 0.0046 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 PSC75743.1 - 0.0033 17.4 0.0 0.0053 16.7 0.0 1.3 1 0 0 1 1 1 1 NACHT domain Mg_chelatase PF01078.21 PSC75743.1 - 0.0046 16.4 0.1 0.0081 15.6 0.1 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI KTI12 PF08433.10 PSC75743.1 - 0.015 14.8 0.0 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_19 PF13245.6 PSC75743.1 - 0.023 15.0 0.0 0.058 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PSC75743.1 - 0.028 14.0 0.0 0.046 13.2 0.0 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region MeaB PF03308.16 PSC75743.1 - 0.028 13.4 0.2 0.062 12.3 0.2 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 PSC75743.1 - 0.095 13.2 0.1 0.36 11.4 0.1 1.7 1 1 0 2 2 2 0 ABC transporter Viral_helicase1 PF01443.18 PSC75743.1 - 0.11 12.2 0.0 0.18 11.5 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase CbiA PF01656.23 PSC75743.1 - 0.11 12.5 0.0 0.25 11.4 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain T2SSE PF00437.20 PSC75743.1 - 0.12 11.4 0.2 0.2 10.7 0.2 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.22 PSC75743.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_25 PF13481.6 PSC75743.1 - 0.14 11.7 1.2 0.78 9.3 0.0 2.6 3 0 0 3 3 2 0 AAA domain TrwB_AAD_bind PF10412.9 PSC75743.1 - 0.16 10.9 0.1 0.32 9.8 0.1 1.4 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.17 PSC75743.1 - 0.18 11.8 0.0 0.27 11.3 0.0 1.2 1 0 0 1 1 1 0 Helicase HerA, central domain Rad17 PF03215.15 PSC75743.1 - 0.2 11.5 0.0 0.35 10.8 0.0 1.2 1 0 0 1 1 1 0 Rad17 P-loop domain Myb_DNA-binding PF00249.31 PSC75744.1 - 1.8e-24 85.6 18.2 5.1e-11 42.6 0.7 5.4 5 0 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC75744.1 - 9.2e-21 73.9 8.6 7.7e-13 48.5 0.4 5.2 4 2 1 5 5 5 4 Myb-like DNA-binding domain Rap1_C PF11626.8 PSC75744.1 - 0.025 14.7 4.5 3.6 7.7 0.5 2.9 2 0 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Pkinase PF00069.25 PSC75745.1 - 5.3e-32 111.2 0.0 6.4e-21 74.9 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain rve PF00665.26 PSC75745.1 - 1.4e-16 60.7 0.0 2.9e-16 59.7 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain Pkinase_Tyr PF07714.17 PSC75745.1 - 2.3e-16 59.9 0.0 2e-11 43.7 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase rve_3 PF13683.6 PSC75745.1 - 0.0011 18.7 0.0 0.0024 17.6 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Methyltransf_24 PF13578.6 PSC75746.1 - 1.7e-06 29.0 0.0 3.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FAA_hydrolase PF01557.18 PSC75747.1 - 4.8e-59 199.7 0.0 7.1e-59 199.1 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family S6PP PF05116.13 PSC75747.1 - 5e-45 154.0 0.0 6.7e-45 153.5 0.0 1.2 1 0 0 1 1 1 1 Sucrose-6F-phosphate phosphohydrolase FAA_hydrolase_N PF09298.11 PSC75747.1 - 1.3e-26 92.9 0.0 2.7e-26 91.9 0.0 1.5 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal Hydrolase_3 PF08282.12 PSC75747.1 - 8.6e-15 55.2 0.0 7.2e-12 45.6 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 PSC75747.1 - 0.00044 20.7 0.2 0.029 14.8 0.0 3.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PSC75747.1 - 0.002 18.5 0.8 0.28 11.5 0.0 3.0 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase GATase_6 PF13522.6 PSC75748.1 - 2.5e-14 53.6 0.0 1.3e-13 51.3 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 PSC75748.1 - 2.3e-12 46.9 0.0 4.6e-12 45.9 0.0 1.5 1 1 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 PSC75748.1 - 2.2e-10 40.3 0.0 1.3e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 PSC75748.1 - 0.013 14.4 0.0 0.022 13.6 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferases class-II TsaE PF02367.17 PSC75749.1 - 4.3e-24 84.9 0.0 7.5e-24 84.1 0.0 1.3 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF2452 PF10504.9 PSC75749.1 - 0.18 11.3 0.0 0.33 10.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2452) ATPase PF06745.13 PSC75749.1 - 0.19 11.0 0.0 0.38 10.1 0.0 1.4 1 0 0 1 1 1 0 KaiC DUF2057 PF09829.9 PSC75749.1 - 0.68 10.1 4.6 0.31 11.2 2.4 1.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) RskA PF10099.9 PSC75749.1 - 1.5 9.1 26.5 1.2 9.4 21.9 2.2 2 0 0 2 2 2 0 Anti-sigma-K factor rskA RBM39linker PF15519.6 PSC75749.1 - 3.3 8.8 11.0 16 6.7 7.4 3.0 2 1 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein Histone_HNS PF00816.21 PSC75750.1 - 0.27 12.1 2.1 0.75 10.7 0.4 2.2 2 0 0 2 2 2 0 H-NS histone family ABC_transp_aux PF09822.9 PSC75751.1 - 3.4e-05 23.5 0.0 4.9e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 ABC-type uncharacterized transport system DUF4350 PF14258.6 PSC75751.1 - 0.056 13.9 0.0 0.14 12.6 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4350) ThuA PF06283.11 PSC75751.1 - 0.068 13.4 0.0 0.39 10.9 0.0 2.1 2 1 1 3 3 3 0 Trehalose utilisation Aminotran_3 PF00202.21 PSC75752.1 - 9.8e-113 376.9 0.0 1.2e-112 376.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Prok-TraM PF09228.10 PSC75753.1 - 0.058 13.8 0.3 0.31 11.4 0.4 2.1 2 0 0 2 2 2 0 Prokaryotic Transcriptional repressor TraM DivIC PF04977.15 PSC75753.1 - 0.13 12.0 5.7 0.29 10.9 5.7 1.5 1 0 0 1 1 1 0 Septum formation initiator Spt20 PF12090.8 PSC75753.1 - 3.5 7.2 8.2 5.4 6.6 8.2 1.2 1 0 0 1 1 1 0 Spt20 family TMEM189_B_dmain PF10520.9 PSC75754.1 - 1.9e-58 197.4 1.7 2.5e-58 197.0 1.7 1.1 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain FA_hydroxylase PF04116.13 PSC75754.1 - 0.011 16.1 3.7 0.014 15.7 2.4 1.8 1 1 1 2 2 2 0 Fatty acid hydroxylase superfamily LRR_8 PF13855.6 PSC75755.1 - 0.19 11.5 0.5 4.3 7.2 0.0 3.4 4 0 0 4 4 4 0 Leucine rich repeat F-box-like PF12937.7 PSC75755.1 - 0.34 10.9 6.0 0.077 12.9 1.1 2.3 2 0 0 2 2 2 0 F-box-like Pkinase PF00069.25 PSC75756.1 - 1.5e-58 198.3 0.0 1.9e-58 197.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC75756.1 - 8e-38 130.2 0.0 1.1e-37 129.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC75756.1 - 2.3e-05 23.9 0.0 5.7e-05 22.6 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PSC75756.1 - 7.7e-05 21.6 0.1 0.00015 20.7 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PSC75756.1 - 0.0016 18.4 0.4 0.052 13.5 0.2 3.8 2 2 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 PSC75756.1 - 0.024 14.0 0.1 0.043 13.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 PSC75756.1 - 0.031 13.9 0.0 0.55 9.8 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 DUF4770 PF15994.5 PSC75756.1 - 0.15 12.3 0.7 3.2 7.9 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) peroxidase PF00141.23 PSC75757.1 - 2.4e-17 63.4 0.5 4e-17 62.7 0.5 1.3 1 0 0 1 1 1 1 Peroxidase PsbQ PF05757.11 PSC75757.1 - 0.25 11.1 4.9 0.58 9.9 4.9 1.6 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) Glyco_hydro_3 PF00933.21 PSC75758.1 - 2.7e-37 128.8 0.0 6.4e-37 127.6 0.0 1.5 1 1 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 PSC75758.1 - 7e-37 127.4 0.0 7e-37 127.4 0.0 2.7 2 1 0 2 2 1 1 Glycosyl hydrolase family 3 C-terminal domain GST_N_2 PF13409.6 PSC75758.1 - 8e-14 51.7 0.0 3.3e-13 49.7 0.0 2.1 3 0 0 3 3 3 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 PSC75758.1 - 4.8e-13 49.3 0.0 1.5e-12 47.7 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PSC75758.1 - 1.4e-07 31.7 0.0 3.6e-07 30.4 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain LRR_4 PF12799.7 PSC75758.1 - 1.1e-05 25.7 0.2 2.3e-05 24.6 0.2 1.6 1 0 0 1 1 1 1 Leucine Rich repeats (2 copies) GST_C_2 PF13410.6 PSC75758.1 - 0.00016 21.6 0.0 0.00058 19.8 0.0 2.0 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain LRR_8 PF13855.6 PSC75758.1 - 0.00075 19.2 1.6 0.0013 18.5 0.8 1.7 2 0 0 2 2 2 1 Leucine rich repeat LRR_6 PF13516.6 PSC75758.1 - 0.009 16.0 0.6 0.75 10.0 0.1 2.7 2 0 0 2 2 2 1 Leucine Rich repeat GST_C_5 PF16865.5 PSC75758.1 - 0.041 14.4 0.0 0.099 13.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Herpes_U34 PF04541.13 PSC75758.1 - 0.2 10.9 0.0 0.51 9.6 0.0 1.6 2 0 0 2 2 2 0 Herpesvirus virion protein U34 NAD_binding_10 PF13460.6 PSC75759.1 - 2.2e-25 89.6 0.0 3.3e-25 89.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 PSC75759.1 - 0.00066 19.3 0.0 0.0011 18.6 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family Peripla_BP_4 PF13407.6 PSC75759.1 - 0.032 13.8 0.0 0.046 13.3 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein domain zf-rbx1 PF12678.7 PSC75760.1 - 1.1e-09 38.5 10.0 3.3e-09 36.9 10.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 PSC75760.1 - 1.8e-09 37.8 13.1 4.1e-09 36.6 13.1 1.6 1 0 0 1 1 1 1 Ring finger domain Radical_SAM PF04055.21 PSC75760.1 - 7.1e-09 36.3 0.1 1.7e-08 35.0 0.1 1.7 1 1 0 1 1 1 1 Radical SAM superfamily zf-C3HC4_2 PF13923.6 PSC75760.1 - 5e-05 23.1 10.5 0.00012 21.9 10.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 PSC75760.1 - 0.00021 21.3 9.1 0.0012 18.8 9.1 2.1 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 PSC75760.1 - 0.00039 20.2 9.5 0.0012 18.7 9.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC75760.1 - 0.00046 20.1 8.9 0.001 19.0 8.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 PSC75760.1 - 0.00073 19.4 11.5 0.0015 18.4 11.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 PSC75760.1 - 0.0018 18.0 8.1 0.0018 18.0 8.1 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 PSC75760.1 - 0.0087 16.0 10.7 0.0087 16.0 10.7 1.8 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 PSC75760.1 - 0.0092 15.8 9.3 0.02 14.7 9.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Fer4_14 PF13394.6 PSC75760.1 - 0.0095 16.1 0.0 0.028 14.5 0.0 1.7 1 1 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 PSC75760.1 - 0.19 12.0 0.1 0.7 10.2 0.1 2.0 2 1 0 2 2 1 0 4Fe-4S single cluster domain FANCL_C PF11793.8 PSC75760.1 - 9.3 6.5 8.5 4.4 7.6 5.5 2.1 2 0 0 2 2 2 0 FANCL C-terminal domain zf-HC5HC2H PF13771.6 PSC75760.1 - 9.8 6.5 14.8 0.092 13.0 6.2 2.0 2 1 0 2 2 1 0 PHD-like zinc-binding domain Pkinase_Tyr PF07714.17 PSC75761.1 - 6.7e-77 258.3 0.0 9.2e-77 257.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC75761.1 - 2.1e-64 217.4 0.0 3e-64 216.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PSC75761.1 - 0.0001 21.7 0.0 0.00017 21.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 PSC75761.1 - 0.00014 20.8 0.0 0.00023 20.1 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 PSC75761.1 - 0.0023 17.9 0.0 0.057 13.3 0.0 2.6 1 1 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 PSC75761.1 - 0.0026 16.8 0.0 0.0044 16.0 0.0 1.4 1 0 0 1 1 1 1 Haspin like kinase domain ACT_6 PF13740.6 PSC75761.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 ACT domain Kdo PF06293.14 PSC75761.1 - 0.13 11.6 0.1 0.26 10.6 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FoP_duplication PF13865.6 PSC75762.1 - 1 9.9 10.0 2 9.0 10.0 1.4 1 0 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Caudo_TAP PF02413.17 PSC75763.1 - 4.3 7.5 5.5 3.2 7.9 1.1 2.4 1 1 1 2 2 2 0 Caudovirales tail fibre assembly protein, lambda gpK PHO4 PF01384.20 PSC75765.1 - 5.2e-118 393.9 12.5 6.7e-118 393.6 12.5 1.1 1 0 0 1 1 1 1 Phosphate transporter family SLC3A2_N PF16028.5 PSC75765.1 - 3 7.4 4.7 6.8 6.3 1.0 3.1 3 0 0 3 3 3 0 Solute carrier family 3 member 2 N-terminus HMMR_N PF15905.5 PSC75767.1 - 0.0029 17.2 3.5 0.0029 17.2 3.5 8.4 3 3 3 7 7 7 5 Hyaluronan mediated motility receptor N-terminal Fez1 PF06818.15 PSC75767.1 - 6 7.3 130.3 0.3 11.5 10.7 9.5 6 2 2 8 8 8 0 Fez1 SYS1 PF09801.9 PSC75768.1 - 4.5e-30 104.7 3.1 5.9e-30 104.3 3.1 1.1 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network DnaJ PF00226.31 PSC75769.1 - 0.00012 22.1 0.0 0.00018 21.6 0.0 1.2 1 0 0 1 1 1 1 DnaJ domain PAS_3 PF08447.12 PSC75769.1 - 0.096 13.0 0.0 0.14 12.5 0.0 1.3 1 0 0 1 1 1 0 PAS fold DUF1772 PF08592.11 PSC75770.1 - 1e-16 61.5 4.4 1e-16 61.5 4.4 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF1772) Metallophos PF00149.28 PSC75771.1 - 2.9e-32 112.8 0.1 4.2e-32 112.3 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 PSC75771.1 - 2.2e-25 88.7 0.4 6.3e-25 87.3 0.1 2.0 2 0 0 2 2 2 1 PPP5 TPR repeat region TPR_1 PF00515.28 PSC75771.1 - 5e-15 54.6 9.6 9.3e-06 25.2 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 PSC75771.1 - 1.5e-14 52.8 13.7 5.1e-07 29.3 0.1 4.1 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 PSC75771.1 - 1.1e-13 50.7 3.4 7.4e-06 25.5 1.4 3.5 1 1 2 3 3 3 3 TPR repeat TPR_17 PF13431.6 PSC75771.1 - 1.2e-10 41.0 0.4 0.0011 19.2 0.1 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 PSC75771.1 - 6.1e-09 35.9 3.2 1.9e-05 24.7 0.5 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 PSC75771.1 - 2.6e-06 28.0 4.6 2.6e-06 28.0 4.6 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 PSC75771.1 - 4.3e-06 26.5 7.3 0.25 11.6 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 PSC75771.1 - 8.4e-06 26.2 9.3 8.1e-05 23.1 0.8 3.9 3 1 2 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 PSC75771.1 - 0.00013 22.4 12.7 0.0015 19.0 1.0 4.2 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 PSC75771.1 - 0.0017 18.6 3.9 0.013 15.8 0.5 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat BTAD PF03704.17 PSC75771.1 - 0.0018 18.8 1.6 0.003 18.0 1.6 1.4 1 0 0 1 1 1 1 Bacterial transcriptional activator domain TPR_6 PF13174.6 PSC75771.1 - 0.12 13.0 0.1 0.12 13.0 0.1 2.4 3 0 0 3 3 1 0 Tetratricopeptide repeat Pyr_redox_2 PF07992.14 PSC75772.1 - 3.6e-63 213.5 0.3 6.2e-63 212.8 0.3 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 PSC75772.1 - 2.6e-31 108.1 0.5 5.4e-31 107.1 0.5 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Peptidase_M14 PF00246.24 PSC75772.1 - 1.6e-22 80.7 0.0 2.5e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Zinc carboxypeptidase Pyr_redox PF00070.27 PSC75772.1 - 5.5e-19 68.5 3.9 6.3e-19 68.3 0.0 3.1 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PSC75772.1 - 4.2e-07 29.5 0.0 1.1e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PSC75772.1 - 0.0035 16.5 0.2 0.04 13.0 0.0 2.1 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pkinase PF00069.25 PSC75773.1 - 1.4e-31 109.9 0.0 3.6e-31 108.5 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain FMN_red PF03358.15 PSC75773.1 - 1.3e-19 70.4 0.0 3.6e-13 49.6 0.0 2.7 2 0 0 2 2 2 2 NADPH-dependent FMN reductase Pkinase_Tyr PF07714.17 PSC75773.1 - 1.5e-09 37.5 0.0 2.2e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Flavodoxin_2 PF02525.17 PSC75773.1 - 4.4e-07 29.8 0.0 0.006 16.3 0.0 2.5 2 0 0 2 2 2 2 Flavodoxin-like fold Kdo PF06293.14 PSC75773.1 - 1.7e-05 24.3 0.0 2.9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PSC75773.1 - 0.099 11.4 0.0 0.15 10.8 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase RIO1 PF01163.22 PSC75773.1 - 0.28 10.8 0.0 0.46 10.1 0.0 1.2 1 0 0 1 1 1 0 RIO1 family DUF4574 PF15141.6 PSC75774.1 - 0.017 15.0 0.4 0.02 14.8 0.4 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 TarH PF02203.15 PSC75774.1 - 0.037 14.0 0.1 0.04 13.9 0.1 1.1 1 0 0 1 1 1 0 Tar ligand binding domain homologue PC-Esterase PF13839.6 PSC75775.1 - 5.4e-09 36.2 15.0 0.15 11.7 0.0 5.2 5 1 0 5 5 5 4 GDSL/SGNH-like Acyl-Esterase family found in Pmr5 and Cas1p Nop14 PF04147.12 PSC75775.1 - 2.3 6.3 4.2 3.1 5.9 4.2 1.0 1 0 0 1 1 1 0 Nop14-like family Trigger_N PF05697.13 PSC75776.1 - 7.8e-18 65.2 0.0 1.3e-17 64.4 0.0 1.4 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) AP2 PF00847.20 PSC75776.1 - 4.2e-11 42.9 0.3 5.2e-05 23.4 0.0 2.7 2 0 0 2 2 2 2 AP2 domain Trigger_C PF05698.14 PSC75776.1 - 2.9e-09 37.1 0.7 7.5e-09 35.8 0.7 1.8 1 0 0 1 1 1 1 Bacterial trigger factor protein (TF) C-terminus DUF167 PF02594.16 PSC75777.1 - 8.4e-06 25.8 0.0 2.1e-05 24.6 0.0 1.7 1 1 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 Jagunal PF07086.12 PSC75778.1 - 0.054 13.6 1.6 0.24 11.4 1.4 2.0 1 1 1 2 2 2 0 Jagunal, ER re-organisation during oogenesis Peptidase_M16 PF00675.20 PSC75779.1 - 2.1e-53 180.3 0.0 3.1e-53 179.8 0.0 1.3 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 PSC75779.1 - 4.3e-34 118.1 0.0 2.7e-33 115.5 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain MFS_1 PF07690.16 PSC75780.1 - 4.5e-58 196.9 40.5 5.7e-58 196.5 34.5 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PSC75780.1 - 1.7e-06 27.2 12.1 1.7e-06 27.2 12.1 2.2 2 0 0 2 2 2 1 Sugar (and other) transporter PHF5 PF03660.14 PSC75780.1 - 2.5 8.4 23.8 3.8 7.8 0.8 4.0 4 0 0 4 4 4 0 PHF5-like protein DUF2358 PF10184.9 PSC75781.1 - 4e-14 52.8 0.0 1.1e-13 51.4 0.0 1.7 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2358) SNARE_assoc PF09335.11 PSC75781.1 - 6.9e-14 52.4 4.2 6.9e-14 52.4 4.2 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein SnoaL_2 PF12680.7 PSC75781.1 - 0.019 15.6 0.0 0.042 14.5 0.0 1.6 1 0 0 1 1 1 0 SnoaL-like domain Med26 PF08711.11 PSC75782.1 - 4.3e-05 23.4 0.0 8.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain GATA PF00320.27 PSC75782.1 - 9.4 5.9 12.2 1.3 8.7 8.0 1.8 2 0 0 2 2 2 0 GATA zinc finger Filamin PF00630.19 PSC75783.1 - 3.3e-06 27.9 0.0 5.9e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Filamin/ABP280 repeat Pkinase PF00069.25 PSC75784.1 - 9e-57 192.4 0.0 1e-31 110.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain PAS_9 PF13426.7 PSC75784.1 - 2.1e-41 140.4 0.0 1e-21 77.1 0.0 2.3 2 0 0 2 2 2 2 PAS domain Pkinase_Tyr PF07714.17 PSC75784.1 - 3.6e-29 101.8 0.0 1.2e-18 67.4 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase PAS_3 PF08447.12 PSC75784.1 - 1.7e-15 57.1 0.0 4.6e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS PF00989.25 PSC75784.1 - 1.6e-12 47.4 0.0 1.1e-05 25.4 0.0 2.4 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 PSC75784.1 - 4.9e-09 36.4 0.0 0.00042 20.5 0.0 2.9 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 PSC75784.1 - 0.016 15.2 0.0 0.37 10.9 0.0 2.5 2 0 0 2 2 2 0 PAS domain Kinase-like PF14531.6 PSC75784.1 - 0.02 14.2 0.1 0.38 10.0 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Pkinase_fungal PF17667.1 PSC75784.1 - 0.084 11.6 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Fungal protein kinase Radical_SAM_C PF16199.5 PSC75785.1 - 1.3e-31 108.5 0.0 2.7e-31 107.4 0.0 1.6 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 PSC75785.1 - 1.6e-16 61.1 0.0 2.6e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 PSC75785.1 - 6.6e-10 39.3 0.1 1.6e-09 38.0 0.1 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PSC75785.1 - 4e-05 23.6 0.2 7.4e-05 22.7 0.2 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PSC75785.1 - 8.7e-05 22.9 0.1 0.00018 21.9 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC75785.1 - 0.028 14.4 0.0 0.081 12.9 0.0 1.7 1 0 0 1 1 1 0 FR47-like protein Exostosin PF03016.15 PSC75786.1 - 8.5e-22 77.7 0.1 8.5e-22 77.7 0.1 2.4 2 1 0 2 2 2 1 Exostosin family TFIIA PF03153.13 PSC75786.1 - 0.019 15.0 27.0 0.031 14.3 27.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 PSC75786.1 - 0.63 10.2 6.8 1.1 9.3 6.8 1.4 1 0 0 1 1 1 0 DDHD domain Ndc1_Nup PF09531.10 PSC75786.1 - 1.8 7.2 5.0 2.7 6.6 5.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TCP PF03634.13 PSC75786.1 - 2.2 8.9 12.7 4.6 7.8 12.7 1.5 1 0 0 1 1 1 0 TCP family transcription factor DDRGK PF09756.9 PSC75786.1 - 2.6 7.6 11.7 4.3 6.9 11.7 1.3 1 0 0 1 1 1 0 DDRGK domain Raftlin PF15250.6 PSC75786.1 - 2.7 6.6 11.6 5.2 5.7 11.6 1.4 1 0 0 1 1 1 0 Raftlin Presenilin PF01080.17 PSC75786.1 - 3.1 6.4 14.9 4.8 5.8 14.9 1.2 1 0 0 1 1 1 0 Presenilin DUF3807 PF12720.7 PSC75786.1 - 7 6.9 16.5 16 5.7 16.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RR_TM4-6 PF06459.12 PSC75786.1 - 7.3 6.3 19.2 0.42 10.4 14.0 1.5 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 GREB1 PF15782.5 PSC75786.1 - 8 3.4 11.0 11 3.0 11.0 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer eIF-3_zeta PF05091.12 PSC75786.1 - 8.6 5.2 11.3 13 4.7 11.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) SAPS PF04499.15 PSC75786.1 - 8.8 5.0 8.2 13 4.4 8.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MMR1 PF08505.10 PSC75786.1 - 9.2 6.5 13.6 15 5.7 13.6 1.3 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein LRR_4 PF12799.7 PSC75787.1 - 1.2e-27 95.5 2.4 0.00017 21.9 0.3 6.2 7 0 0 7 7 7 5 Leucine Rich repeats (2 copies) AP2 PF00847.20 PSC75787.1 - 3.6e-09 36.7 6.9 0.012 15.8 2.1 4.9 4 0 0 4 4 4 3 AP2 domain LRR_8 PF13855.6 PSC75787.1 - 3.9e-08 32.9 21.7 0.04 13.7 5.5 5.8 4 1 3 7 7 7 6 Leucine rich repeat LRR_6 PF13516.6 PSC75787.1 - 3.1e-05 23.7 7.1 1.2 9.4 0.0 6.2 6 0 0 6 6 6 1 Leucine Rich repeat LRR_9 PF14580.6 PSC75787.1 - 0.0004 19.9 0.0 0.04 13.4 0.0 2.4 2 0 0 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.33 PSC75787.1 - 0.0032 17.8 7.1 6 7.8 0.0 6.8 7 1 0 7 7 7 1 Leucine Rich Repeat IQ PF00612.27 PSC75787.1 - 0.034 13.9 24.9 0.024 14.4 2.5 4.6 4 0 0 4 4 4 0 IQ calmodulin-binding motif SOBP PF15279.6 PSC75787.1 - 2.1 8.9 40.0 8.9 6.8 20.9 2.8 2 0 0 2 2 2 0 Sine oculis-binding protein Nuc_sug_transp PF04142.15 PSC75788.1 - 5.7e-32 111.1 10.4 7.4e-32 110.8 10.4 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 PSC75788.1 - 0.0036 17.5 4.1 0.0036 17.5 4.1 2.4 2 1 0 2 2 2 2 EamA-like transporter family His_Phos_1 PF00300.22 PSC75791.1 - 3.9e-38 131.1 8.2 9.2e-22 77.7 1.4 3.5 4 0 0 4 4 4 2 Histidine phosphatase superfamily (branch 1) PsbY PF06298.11 PSC75791.1 - 1.3e-17 63.3 18.2 0.0063 16.4 0.3 5.9 5 0 0 5 5 5 5 Photosystem II protein Y (PsbY) Shikimate_dh_N PF08501.11 PSC75791.1 - 0.067 13.5 0.0 40 4.6 0.0 3.5 3 0 0 3 3 3 0 Shikimate dehydrogenase substrate binding domain DUF3100 PF11299.8 PSC75791.1 - 9.6 5.5 29.7 0.55 9.6 0.3 5.1 2 1 3 5 5 5 0 Protein of unknown function (DUF3100) MAGE PF01454.19 PSC75792.1 - 5.5e-19 68.7 0.0 8.4e-19 68.1 0.0 1.2 1 0 0 1 1 1 1 MAGE family Prothymosin PF03247.14 PSC75792.1 - 2.4 8.7 11.2 4.5 7.8 11.2 1.4 1 0 0 1 1 1 0 Prothymosin/parathymosin family AAA PF00004.29 PSC75793.1 - 1.1e-45 155.3 0.1 1.8e-44 151.4 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PSC75793.1 - 6.5e-09 35.9 0.1 2.5e-08 34.0 0.1 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 PSC75793.1 - 1.1e-08 34.9 0.1 8.2e-08 32.1 0.0 2.4 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 PSC75793.1 - 2.3e-06 28.1 1.8 8.8e-05 23.0 0.0 2.7 2 2 1 3 3 3 1 AAA ATPase domain AAA_2 PF07724.14 PSC75793.1 - 5e-06 26.7 0.3 1.3e-05 25.4 0.0 1.9 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 PSC75793.1 - 6.5e-06 25.5 0.4 3e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_lid_3 PF17862.1 PSC75793.1 - 1e-05 25.2 0.0 2.6e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 PSC75793.1 - 3.9e-05 23.9 0.6 0.0073 16.6 0.1 2.7 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 PSC75793.1 - 9.1e-05 22.2 0.0 0.00037 20.3 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 PSC75793.1 - 0.00023 21.7 0.0 0.001 19.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 PSC75793.1 - 0.0004 20.2 0.2 0.0024 17.7 0.0 2.3 2 1 1 3 3 2 1 IstB-like ATP binding protein AAA_28 PF13521.6 PSC75793.1 - 0.00041 20.6 0.1 0.0013 19.1 0.0 1.9 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.15 PSC75793.1 - 0.00054 19.9 0.2 0.022 14.7 0.0 2.9 3 0 0 3 3 3 1 NTPase RNA_helicase PF00910.22 PSC75793.1 - 0.00075 19.9 0.0 0.0017 18.7 0.0 1.6 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 PSC75793.1 - 0.0016 17.9 0.0 0.0035 16.7 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 PSC75793.1 - 0.0016 18.1 0.3 0.16 11.6 0.0 3.2 3 0 0 3 3 3 1 Sigma-54 interaction domain TIP49 PF06068.13 PSC75793.1 - 0.0023 17.2 0.1 0.0061 15.8 0.1 1.7 1 1 0 1 1 1 1 TIP49 P-loop domain AAA_30 PF13604.6 PSC75793.1 - 0.0029 17.3 0.0 0.011 15.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PSC75793.1 - 0.0034 17.5 0.1 0.011 15.9 0.0 1.7 1 1 0 1 1 1 1 AAA domain TsaE PF02367.17 PSC75793.1 - 0.0037 17.2 0.0 0.008 16.2 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 PSC75793.1 - 0.005 16.4 1.2 0.023 14.3 0.9 2.2 1 1 1 2 2 2 1 AAA domain NACHT PF05729.12 PSC75793.1 - 0.006 16.5 0.5 0.077 12.9 0.0 2.7 4 0 0 4 4 3 1 NACHT domain AAA_23 PF13476.6 PSC75793.1 - 0.0083 16.6 0.4 7.3 7.0 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_24 PF13479.6 PSC75793.1 - 0.0085 15.8 0.2 0.024 14.4 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 PSC75793.1 - 0.01 15.9 0.0 0.049 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_3 PF07726.11 PSC75793.1 - 0.01 15.7 0.1 0.044 13.6 0.0 2.1 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 PSC75793.1 - 0.013 15.0 0.1 0.063 12.8 0.1 2.0 1 1 0 1 1 1 0 P-loop containing dynein motor region Parvo_NS1 PF01057.17 PSC75793.1 - 0.016 14.3 0.0 0.035 13.2 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.6 PSC75793.1 - 0.02 15.0 0.3 1.4 9.0 0.0 2.9 3 1 0 3 3 2 0 Sigma-54 interaction domain TniB PF05621.11 PSC75793.1 - 0.038 13.4 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein T2SSE PF00437.20 PSC75793.1 - 0.071 12.2 0.0 0.21 10.6 0.0 1.8 1 1 0 1 1 1 0 Type II/IV secretion system protein AAA_11 PF13086.6 PSC75793.1 - 0.076 12.8 0.0 0.25 11.1 0.0 1.9 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 PSC75793.1 - 0.079 12.4 0.0 0.18 11.2 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein ATPase_2 PF01637.18 PSC75793.1 - 0.097 12.6 1.1 1.5 8.7 0.0 2.5 2 1 0 3 3 2 0 ATPase domain predominantly from Archaea NB-ARC PF00931.22 PSC75793.1 - 0.11 11.6 0.0 0.3 10.2 0.0 1.7 1 0 0 1 1 1 0 NB-ARC domain MCM PF00493.23 PSC75793.1 - 0.12 11.5 0.0 0.23 10.5 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain AAA_19 PF13245.6 PSC75793.1 - 0.15 12.4 0.2 0.58 10.5 0.1 2.0 2 0 0 2 2 1 0 AAA domain ATPase PF06745.13 PSC75793.1 - 0.39 10.0 0.0 0.39 10.0 0.0 2.2 3 0 0 3 3 3 0 KaiC SLBP_RNA_bind PF15247.6 PSC75794.1 - 2.3e-28 98.1 3.1 2.3e-28 98.1 3.1 1.9 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain RRM_1 PF00076.22 PSC75795.1 - 1.5e-08 34.4 0.0 3.2e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RNA_bind PF08675.11 PSC75795.1 - 0.00064 19.7 0.0 0.0012 18.9 0.0 1.4 1 0 0 1 1 1 1 RNA binding domain TraB PF01963.17 PSC75796.1 - 7.9e-16 58.7 0.7 1.5e-07 31.6 0.1 2.3 2 0 0 2 2 2 2 TraB family DUF2020 PF09449.10 PSC75796.1 - 0.29 10.9 2.1 0.53 10.1 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF2020) RabGAP-TBC PF00566.18 PSC75797.1 - 1.6e-38 132.5 0.0 2.3e-38 132.0 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain FANCI_S1 PF14675.6 PSC75797.1 - 0.21 11.1 0.1 0.32 10.5 0.1 1.2 1 0 0 1 1 1 0 FANCI solenoid 1 RabGAP-TBC PF00566.18 PSC75798.1 - 2.9e-38 131.7 0.0 4e-38 131.2 0.0 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain LRR_4 PF12799.7 PSC75798.1 - 0.051 14.0 4.7 2.9 8.4 0.0 4.9 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Peptidase_C65 PF10275.9 PSC75800.1 - 1.1e-64 218.2 0.0 1.4e-64 217.9 0.0 1.1 1 0 0 1 1 1 1 Peptidase C65 Otubain OTU PF02338.19 PSC75800.1 - 0.079 13.5 0.0 5.6 7.5 0.0 2.3 2 0 0 2 2 2 0 OTU-like cysteine protease TF_Zn_Ribbon PF08271.12 PSC75801.1 - 0.002 17.6 0.4 0.0038 16.7 0.4 1.5 1 0 0 1 1 1 1 TFIIB zinc-binding GntR PF00392.21 PSC75801.1 - 0.0082 15.8 0.1 0.019 14.6 0.1 1.6 1 0 0 1 1 1 1 Bacterial regulatory proteins, gntR family Zn-ribbon_8 PF09723.10 PSC75801.1 - 0.094 12.8 0.9 0.27 11.4 0.9 1.8 1 1 0 1 1 1 0 Zinc ribbon domain Ribosomal_S25 PF03297.15 PSC75801.1 - 0.14 12.4 0.1 0.14 12.4 0.1 2.3 2 0 0 2 2 2 0 S25 ribosomal protein ACBP PF00887.19 PSC75802.1 - 1.1e-28 99.2 0.8 1.3e-28 99.1 0.8 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein VEGF_C PF14554.6 PSC75803.1 - 0.058 13.5 0.5 0.2 11.7 0.1 2.0 2 0 0 2 2 2 0 VEGF heparin-binding domain PseudoU_synth_2 PF00849.22 PSC75804.1 - 3.2e-28 98.8 0.9 1.8e-27 96.4 0.9 2.0 1 1 0 1 1 1 1 RNA pseudouridylate synthase Lin-8 PF03353.15 PSC75804.1 - 6.9 6.1 11.8 0.12 11.9 3.4 1.9 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist CPSF100_C PF13299.6 PSC75804.1 - 7.9 6.6 11.3 0.48 10.6 5.1 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal DEAD PF00270.29 PSC75805.1 - 2.2e-44 151.3 0.0 3.5e-44 150.7 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC75805.1 - 6.4e-20 71.6 0.0 8.3e-19 68.0 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC75805.1 - 6.3e-06 26.3 0.0 1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 PSC75805.1 - 0.0002 20.7 0.1 0.00029 20.1 0.1 1.2 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase DUF2726 PF10881.8 PSC75805.1 - 0.12 12.3 0.0 0.28 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2726) Citrate_synt PF00285.21 PSC75806.1 - 8.3e-129 429.7 0.0 1.5e-128 428.9 0.0 1.4 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Pkinase PF00069.25 PSC75806.1 - 1.5e-63 214.6 0.0 8.1e-63 212.2 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC75806.1 - 4.3e-25 88.5 0.0 8.7e-25 87.5 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_2 PF12796.7 PSC75806.1 - 0.0038 17.8 0.0 0.013 16.1 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC75806.1 - 0.099 13.3 0.0 46 4.8 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Peptidase_C97 PF05903.14 PSC75807.1 - 8.6e-40 136.0 0.0 1e-39 135.8 0.0 1.1 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 PSC75807.1 - 0.055 13.8 0.2 0.091 13.1 0.0 1.4 2 0 0 2 2 2 0 Lecithin retinol acyltransferase COOH-NH2_lig PF14395.6 PSC75807.1 - 0.072 12.3 0.0 0.093 11.9 0.0 1.1 1 0 0 1 1 1 0 Phage phiEco32-like COOH.NH2 ligase-type 2 eRF1_2 PF03464.15 PSC75808.1 - 4.1e-44 150.1 0.0 7.1e-44 149.4 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 PSC75808.1 - 1.3e-35 122.3 0.1 2.3e-35 121.5 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 PSC75808.1 - 7.6e-20 71.2 0.1 1.4e-19 70.3 0.0 1.5 2 0 0 2 2 2 1 eRF1 domain 1 acVLRF1 PF18859.1 PSC75808.1 - 4.1e-08 33.6 0.0 6.5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor baeRF_family10 PF18854.1 PSC75808.1 - 1.3e-07 31.9 0.0 2.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 UCH PF00443.29 PSC75809.1 - 5.3e-11 42.5 0.0 7.9e-10 38.6 0.0 2.7 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Helicase_C PF00271.31 PSC75809.1 - 5.7e-09 36.3 0.0 1.2e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 PSC75809.1 - 6.8e-05 22.7 2.5 6.8e-05 22.7 2.5 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC75809.1 - 0.00068 19.9 2.4 0.00068 19.9 2.4 2.7 3 0 0 3 3 2 1 Ring finger domain UCH_1 PF13423.6 PSC75809.1 - 0.0014 18.3 0.0 0.055 13.1 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-RING_5 PF14634.6 PSC75809.1 - 0.0025 17.7 2.6 0.0025 17.7 2.6 2.7 3 0 0 3 3 3 1 zinc-RING finger domain zf-C3HC4 PF00097.25 PSC75809.1 - 0.0057 16.5 2.1 0.0057 16.5 2.1 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 PSC75809.1 - 0.31 10.8 1.8 0.7 9.7 1.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 PSC75809.1 - 0.64 10.2 3.4 1.4 9.1 3.4 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 PSC75809.1 - 1.6 8.5 8.3 0.72 9.6 1.9 3.1 3 0 0 3 3 3 0 RING-like zinc finger Prok-RING_4 PF14447.6 PSC75809.1 - 5 7.1 8.6 0.44 10.4 3.5 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 RRM_1 PF00076.22 PSC75810.1 - 4.4e-18 64.9 0.0 1.1e-07 31.5 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 PSC75810.1 - 1.8e-09 37.3 0.0 5.2e-09 35.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 PSC75810.1 - 3e-09 37.0 0.2 7.9e-09 35.6 0.2 1.6 1 0 0 1 1 1 1 RRM-like domain RRM_occluded PF16842.5 PSC75810.1 - 0.00036 20.3 1.9 1.3 9.0 0.0 3.9 4 0 0 4 4 4 2 Occluded RNA-recognition motif Abhydrolase_6 PF12697.7 PSC75811.1 - 2 9.0 15.3 0.23 12.1 9.9 2.1 1 1 1 2 2 2 0 Alpha/beta hydrolase family AAA PF00004.29 PSC75812.1 - 5e-42 143.4 0.0 1e-41 142.4 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 PSC75812.1 - 1.6e-19 69.6 0.2 3.1e-19 68.7 0.2 1.5 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 PSC75812.1 - 1.3e-12 47.3 0.6 1.3e-12 47.3 0.6 2.1 3 0 0 3 3 1 1 AAA+ lid domain AAA_5 PF07728.14 PSC75812.1 - 7.2e-07 29.3 0.8 2.9e-06 27.3 0.1 2.4 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 PSC75812.1 - 2.2e-06 28.2 1.6 0.0003 21.2 0.1 2.7 2 1 0 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 PSC75812.1 - 6.4e-06 26.4 0.1 2.6e-05 24.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 PSC75812.1 - 0.00012 22.4 0.7 0.013 15.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.12 PSC75812.1 - 0.00036 20.3 0.0 0.00086 19.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 PSC75812.1 - 0.003 16.8 0.0 0.0056 15.9 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 PSC75812.1 - 0.0031 17.7 0.1 0.0084 16.3 0.1 1.8 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 PSC75812.1 - 0.0071 15.9 0.0 0.021 14.3 0.0 1.7 1 1 0 1 1 1 1 P-loop containing dynein motor region ATPase PF06745.13 PSC75812.1 - 0.0097 15.3 0.1 0.076 12.4 0.0 2.3 2 0 0 2 2 2 1 KaiC PhoH PF02562.16 PSC75812.1 - 0.012 15.0 0.1 0.038 13.4 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 PSC75812.1 - 0.016 14.6 0.1 0.056 12.8 0.1 1.8 1 1 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 PSC75812.1 - 0.016 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_11 PF13086.6 PSC75812.1 - 0.019 14.7 1.1 0.082 12.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.26 PSC75812.1 - 0.02 14.6 0.1 0.16 11.6 0.1 2.5 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.6 PSC75812.1 - 0.025 14.3 0.0 0.08 12.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.13 PSC75812.1 - 0.025 13.8 0.0 0.057 12.6 0.0 1.6 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_18 PF13238.6 PSC75812.1 - 0.025 15.1 0.1 0.17 12.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain CPT PF07931.12 PSC75812.1 - 0.025 14.4 0.0 0.05 13.4 0.0 1.5 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein AAA_14 PF13173.6 PSC75812.1 - 0.035 14.2 0.0 0.091 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 PSC75812.1 - 0.041 13.8 0.2 0.19 11.6 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Prot_ATP_OB_N PF17758.1 PSC75812.1 - 0.064 12.9 0.0 0.63 9.7 0.0 2.4 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_28 PF13521.6 PSC75812.1 - 0.092 13.0 0.0 0.3 11.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 PSC75812.1 - 0.099 12.6 0.2 1.3 8.9 0.0 2.2 1 1 1 2 2 2 0 NACHT domain ABC_tran PF00005.27 PSC75812.1 - 0.11 13.0 0.3 0.78 10.3 0.0 2.4 2 1 0 2 2 2 0 ABC transporter AAA_19 PF13245.6 PSC75812.1 - 0.15 12.4 2.1 0.6 10.4 0.2 2.3 2 1 0 2 2 2 0 AAA domain KELK PF15796.5 PSC75812.1 - 0.33 11.4 5.6 0.39 11.2 2.4 2.6 2 0 0 2 2 2 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase BRAP2 PF07576.12 PSC75814.1 - 4.4e-28 97.4 0.0 7.7e-28 96.6 0.0 1.4 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 PSC75814.1 - 2.3e-19 69.4 7.3 2.5e-19 69.3 5.7 1.9 2 0 0 2 2 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 PSC75814.1 - 7.3e-09 35.8 7.4 7.3e-09 35.8 7.4 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 PSC75814.1 - 2.5e-07 30.4 5.7 2.5e-07 30.4 5.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 PSC75814.1 - 1.1e-05 25.6 5.3 1.1e-05 25.6 5.3 2.3 2 0 0 2 2 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 PSC75814.1 - 1.4e-05 24.9 5.4 1.4e-05 24.9 5.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC75814.1 - 0.00055 19.9 3.8 0.00055 19.9 3.8 2.8 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 PSC75814.1 - 0.0015 18.2 3.4 0.0015 18.2 3.4 2.4 2 1 0 2 2 2 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 PSC75814.1 - 0.041 13.7 20.7 0.12 12.3 8.5 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) UPF0242 PF06785.11 PSC75814.1 - 0.086 12.9 4.9 0.13 12.4 4.9 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-ANAPC11 PF12861.7 PSC75814.1 - 0.2 11.7 9.6 0.04 14.0 5.8 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 PSC75814.1 - 0.84 9.6 20.7 0.42 10.5 4.6 3.6 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 CREPT PF16566.5 PSC75814.1 - 0.97 9.6 4.9 2 8.6 4.9 1.4 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour SKG6 PF08693.10 PSC75814.1 - 0.98 8.9 2.9 1.8 8.0 2.9 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-RING_4 PF14570.6 PSC75814.1 - 1.8 8.5 8.3 0.082 12.7 2.6 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain APG6_N PF17675.1 PSC75814.1 - 2.9 8.4 13.7 7.2 7.1 13.6 1.7 1 1 0 1 1 1 0 Apg6 coiled-coil region Rrp15p PF07890.12 PSC75816.1 - 5.3e-16 59.2 14.9 5.3e-16 59.2 14.9 2.6 2 1 0 2 2 2 1 Rrp15p OB_NTP_bind PF07717.16 PSC75817.1 - 4.8e-25 87.7 0.0 9e-25 86.9 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 PSC75817.1 - 9.3e-24 83.8 1.6 1.8e-23 82.9 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 PSC75817.1 - 2.4e-12 47.2 0.0 8.7e-12 45.4 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 PSC75817.1 - 1.7e-08 34.5 0.6 4e-08 33.2 0.6 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase S1 PF00575.23 PSC75817.1 - 3.6e-08 33.6 0.0 8.1e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 S1 RNA binding domain AAA_22 PF13401.6 PSC75817.1 - 1.9e-06 28.2 1.8 5.1e-06 26.8 0.1 2.5 3 0 0 3 3 2 1 AAA domain AAA_19 PF13245.6 PSC75817.1 - 0.00062 20.1 0.3 0.0019 18.5 0.3 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 PSC75817.1 - 0.0015 18.3 0.9 0.0045 16.7 0.1 2.2 2 0 0 2 2 2 1 AAA domain DUF2075 PF09848.9 PSC75817.1 - 0.0031 16.8 0.0 0.0054 16.0 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) Strep_pep PF14404.6 PSC75817.1 - 0.0053 17.0 0.3 0.13 12.5 0.1 2.7 2 0 0 2 2 2 1 Ribosomally synthesized peptide in Streptomyces species T2SSE PF00437.20 PSC75817.1 - 0.013 14.5 0.0 0.029 13.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 PSC75817.1 - 0.054 13.0 0.1 0.15 11.5 0.1 1.8 1 0 0 1 1 1 0 PhoH-like protein Flavi_DEAD PF07652.14 PSC75817.1 - 0.1 12.6 0.1 0.24 11.4 0.1 1.6 1 0 0 1 1 1 0 Flavivirus DEAD domain ABC_tran PF00005.27 PSC75817.1 - 0.1 13.1 1.0 0.95 10.0 0.2 2.5 1 1 1 2 2 2 0 ABC transporter AAA_24 PF13479.6 PSC75817.1 - 0.12 12.0 0.0 0.3 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Microtub_bd PF16796.5 PSC75817.1 - 0.15 11.9 0.2 3.2 7.7 0.1 2.4 2 0 0 2 2 2 0 Microtubule binding AAA_14 PF13173.6 PSC75817.1 - 0.19 11.8 0.2 1.2 9.2 0.2 2.3 1 1 0 1 1 1 0 AAA domain PNTB PF02233.16 PSC75818.1 - 1.1e-166 555.3 26.7 1.1e-166 555.3 26.7 2.1 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit PNTB_4TM PF12769.7 PSC75818.1 - 1.2e-30 105.8 3.9 1.2e-30 105.8 3.9 4.5 4 2 1 5 5 5 1 4TM region of pyridine nucleotide transhydrogenase, mitoch TPP_enzyme_M PF00205.22 PSC75818.1 - 0.005 16.6 6.2 0.011 15.4 1.5 3.3 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain PGK PF00162.19 PSC75819.1 - 4.7e-163 542.5 0.1 6e-163 542.2 0.1 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase PGK PF00162.19 PSC75820.1 - 4.4e-163 542.6 0.1 5.6e-163 542.3 0.1 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase LSM PF01423.22 PSC75821.1 - 4.8e-20 71.0 0.1 6.2e-20 70.7 0.1 1.1 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 PSC75821.1 - 0.042 13.5 0.0 0.067 12.8 0.0 1.2 1 0 0 1 1 1 0 Hfq protein TPR_1 PF00515.28 PSC75822.1 - 1.8e-09 37.0 9.0 2.2e-06 27.2 0.3 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 PSC75822.1 - 1.8e-09 37.0 13.6 0.00018 21.4 0.2 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 PSC75822.1 - 0.0001 22.5 9.3 0.065 13.5 4.3 3.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 PSC75822.1 - 0.00056 19.9 4.8 0.0012 18.9 0.1 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.6 PSC75822.1 - 0.00062 19.6 0.3 0.00062 19.6 0.3 3.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 PSC75822.1 - 0.0023 18.2 0.7 3.9 8.1 0.1 3.1 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 PSC75822.1 - 0.0051 17.5 0.2 0.0051 17.5 0.2 5.4 4 1 2 6 6 6 2 Tetratricopeptide repeat TPR_10 PF13374.6 PSC75822.1 - 0.0092 15.8 0.2 0.0092 15.8 0.2 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat Metal_resist PF13801.6 PSC75822.1 - 0.017 15.3 2.2 0.017 15.3 2.2 4.2 4 1 0 4 4 4 0 Heavy-metal resistance TPR_19 PF14559.6 PSC75822.1 - 0.023 15.2 6.2 0.16 12.5 1.3 3.2 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 PSC75822.1 - 1.3 9.7 18.3 1.8 9.3 6.1 4.0 2 2 0 2 2 2 0 Tetratricopeptide repeat PP2C PF00481.21 PSC75823.1 - 4e-32 111.9 0.0 1.6e-23 83.6 0.0 2.6 2 0 0 2 2 2 2 Protein phosphatase 2C SUIM_assoc PF16619.5 PSC75823.1 - 5 7.3 19.6 0.089 12.9 0.7 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DnaJ_C PF01556.18 PSC75824.1 - 2.7e-34 118.4 0.0 4.3e-34 117.7 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PSC75824.1 - 4.2e-22 78.1 2.3 7.8e-22 77.2 0.9 2.1 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 PSC75824.1 - 3.1e-12 46.7 21.0 6.7e-12 45.6 21.0 1.6 1 0 0 1 1 1 1 DnaJ central domain Exo_endo_phos PF03372.23 PSC75824.1 - 1.8e-08 34.2 0.1 6.1e-08 32.5 0.1 2.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family UPF0121 PF03661.13 PSC75824.1 - 6.5e-06 25.7 1.8 1.4e-05 24.7 1.8 1.4 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) Glyco_hydro_2_N PF02837.18 PSC75824.1 - 0.011 15.6 0.0 0.025 14.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolases family 2, sugar binding domain Glyco_hydro_2 PF00703.21 PSC75824.1 - 0.031 14.9 0.0 0.087 13.5 0.0 1.7 1 0 0 1 1 1 0 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 PSC75824.1 - 0.081 12.0 0.0 0.19 10.8 0.0 1.5 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain Ig_mannosidase PF17753.1 PSC75824.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 Ig-fold domain zinc-ribbons_6 PF07191.12 PSC75824.1 - 0.17 11.9 8.9 0.36 10.8 8.9 1.5 1 0 0 1 1 1 0 zinc-ribbons Exo_endo_phos_2 PF14529.6 PSC75824.1 - 0.23 11.3 0.0 0.7 9.8 0.0 1.8 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase DUF1764 PF08576.10 PSC75824.1 - 0.34 11.8 2.3 1.2 10.1 2.3 1.9 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Cytochrome_C7 PF14522.6 PSC75824.1 - 4.3 7.4 9.8 0.11 12.5 2.8 2.0 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c zf-LSD1 PF06943.12 PSC75824.1 - 6.2 6.8 9.1 0.13 12.1 0.8 2.7 2 0 0 2 2 1 0 LSD1 zinc finger Anti-TRAP PF15777.5 PSC75824.1 - 8.6 6.4 17.6 3.5 7.6 3.8 2.8 1 1 1 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein TLC PF03219.14 PSC75825.1 - 9e-115 384.2 5.6 4.1e-63 213.8 2.1 2.1 2 0 0 2 2 2 2 TLC ATP/ADP transporter JAB PF01398.21 PSC75825.1 - 1.7e-17 63.5 0.0 2.9e-17 62.7 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 PSC75825.1 - 2.2e-14 53.8 0.0 4.3e-14 52.9 0.0 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Fasciclin PF02469.22 PSC75826.1 - 1.5e-08 34.9 0.0 2.2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Fasciclin domain WD40 PF00400.32 PSC75827.1 - 2.3e-11 44.0 0.0 0.024 15.5 0.0 8.2 9 0 0 9 9 9 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC75827.1 - 1.5e-06 28.4 0.8 6.3 7.2 0.0 6.6 6 1 1 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain Metallophos PF00149.28 PSC75828.1 - 0.0026 18.3 0.0 0.0051 17.3 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L27e PF01777.18 PSC75829.1 - 5.2e-31 106.9 4.1 7.6e-31 106.3 4.1 1.2 1 0 0 1 1 1 1 Ribosomal L27e protein family KOW PF00467.29 PSC75829.1 - 2.1e-05 24.3 0.2 4.3e-05 23.3 0.2 1.6 1 0 0 1 1 1 1 KOW motif DUF2855 PF11017.8 PSC75829.1 - 0.04 13.7 0.1 0.048 13.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) DUF826 PF05696.11 PSC75829.1 - 0.15 12.2 0.4 0.33 11.1 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF826) BAT2_N PF07001.11 PSC75830.1 - 0.27 11.7 3.6 0.43 11.0 3.6 1.2 1 0 0 1 1 1 0 BAT2 N-terminus 3Beta_HSD PF01073.19 PSC75831.1 - 3.7e-71 239.4 0.0 7e-71 238.5 0.0 1.4 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 PSC75831.1 - 3.8e-37 128.0 0.2 5.6e-37 127.5 0.2 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 PSC75831.1 - 1.1e-17 64.0 0.0 1.5e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.6 PSC75831.1 - 7.6e-17 61.8 0.3 1.2e-16 61.2 0.3 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 PSC75831.1 - 2.5e-16 60.0 0.3 9.4e-15 54.8 0.5 2.5 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 PSC75831.1 - 3.1e-15 56.1 0.5 2.4e-10 40.0 0.5 2.3 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.15 PSC75831.1 - 1.3e-09 37.6 1.0 7.7e-09 35.1 1.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Pet100 PF09803.9 PSC75831.1 - 6.9e-05 23.3 0.0 0.00014 22.3 0.0 1.5 1 0 0 1 1 1 1 Pet100 KR PF08659.10 PSC75831.1 - 0.00015 21.8 1.9 0.0046 16.9 0.7 2.7 2 1 0 2 2 2 1 KR domain NmrA PF05368.13 PSC75831.1 - 0.00056 19.5 0.6 0.002 17.7 0.6 1.8 2 1 0 2 2 2 1 NmrA-like family adh_short PF00106.25 PSC75831.1 - 0.023 14.1 0.6 0.056 12.9 0.6 1.7 1 1 0 1 1 1 0 short chain dehydrogenase NYD-SP28 PF14772.6 PSC75832.1 - 1.9e-07 31.0 4.5 1.9e-07 31.0 4.5 4.0 2 1 0 3 3 3 1 Sperm tail DUF4400 PF14348.6 PSC75832.1 - 5.2 6.5 8.2 3.8 7.0 3.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4400) DUF4600 PF15372.6 PSC75832.1 - 7.6 7.0 11.5 4.7 7.7 7.4 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4600) HDAC4_Gln PF12203.8 PSC75832.1 - 9.4 6.5 10.5 1.7 8.9 1.7 3.4 2 2 1 3 3 3 0 Glutamine rich N terminal domain of histone deacetylase 4 DJ-1_PfpI PF01965.24 PSC75833.1 - 7.7e-53 178.7 0.0 8.9e-53 178.5 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 PSC75833.1 - 5.2e-05 23.0 0.1 0.00071 19.3 0.0 2.2 1 1 1 2 2 2 1 ThiJ/PfpI family-like GATase PF00117.28 PSC75833.1 - 0.0001 22.2 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 PSC75833.1 - 0.0044 16.6 0.0 0.0071 16.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 PSC75833.1 - 0.029 14.1 0.0 0.053 13.3 0.0 1.5 1 1 0 1 1 1 0 Peptidase C26 Catalase_C PF18011.1 PSC75833.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 C-terminal domain found in long catalases FANCI_S2 PF14676.6 PSC75835.1 - 8.6e-43 146.5 0.0 2.4e-42 145.0 0.0 1.9 1 0 0 1 1 1 1 FANCI solenoid 2 FANCI_S4 PF14678.6 PSC75835.1 - 6.1e-38 130.4 0.0 1e-37 129.6 0.0 1.3 1 0 0 1 1 1 1 FANCI solenoid 4 FANCI_HD2 PF14680.6 PSC75835.1 - 3.1e-31 108.4 0.0 5.7e-31 107.6 0.0 1.3 1 0 0 1 1 1 1 FANCI helical domain 2 FANCI_S1 PF14675.6 PSC75835.1 - 1e-21 77.6 0.0 2.3e-21 76.4 0.0 1.6 1 0 0 1 1 1 1 FANCI solenoid 1 FANCI_HD1 PF14679.6 PSC75835.1 - 9.8e-10 38.3 0.0 3.4e-09 36.5 0.0 1.9 2 0 0 2 2 2 1 FANCI helical domain 1 PGA2 PF07543.12 PSC75835.1 - 5.1 7.1 11.2 0.093 12.7 1.7 2.5 2 0 0 2 2 2 0 Protein trafficking PGA2 adh_short PF00106.25 PSC75836.1 - 4.7e-54 182.8 4.5 5.7e-54 182.6 4.5 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC75836.1 - 6e-54 183.1 2.7 1.2e-53 182.1 2.7 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC75836.1 - 2.8e-08 33.9 2.1 4.4e-08 33.2 2.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PSC75836.1 - 0.02 14.4 0.2 0.028 13.9 0.2 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_3 PF03447.16 PSC75836.1 - 0.036 14.7 0.0 0.11 13.2 0.0 1.7 1 0 0 1 1 1 0 Homoserine dehydrogenase, NAD binding domain DUF2240 PF09999.9 PSC75836.1 - 0.038 13.6 0.1 0.63 9.7 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2240) BRCT PF00533.26 PSC75837.1 - 2.4e-10 40.6 0.0 7e-05 23.1 0.0 3.1 3 1 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PSC75837.1 - 6e-10 39.4 0.0 3.6e-06 27.3 0.0 3.0 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 PSC75837.1 - 0.00019 21.3 0.1 0.0065 16.3 0.0 2.7 3 0 0 3 3 3 1 Regulator of Ty1 transposition protein 107 BRCT domain PTCB-BRCT PF12738.7 PSC75837.1 - 0.022 14.7 0.0 0.79 9.7 0.0 2.5 2 0 0 2 2 2 0 twin BRCT domain FmiP_Thoc5 PF09766.9 PSC75837.1 - 0.31 10.3 8.2 0.48 9.7 8.2 1.2 1 0 0 1 1 1 0 Fms-interacting protein/Thoc5 DUF4407 PF14362.6 PSC75837.1 - 1.5 8.1 6.0 3.8 6.8 6.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) U79_P34 PF03064.16 PSC75837.1 - 1.6 8.0 4.6 2.8 7.2 4.6 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 SAM_2 PF07647.17 PSC75839.1 - 5.3e-07 29.7 0.0 1.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 PSC75839.1 - 0.00022 21.6 0.0 0.00045 20.6 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Prefoldin_2 PF01920.20 PSC75839.1 - 0.068 13.1 3.5 6.7 6.7 0.3 2.7 2 0 0 2 2 2 0 Prefoldin subunit DUF2523 PF10734.9 PSC75839.1 - 2.1 9.0 5.0 0.59 10.8 0.7 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2523) Spt20 PF12090.8 PSC75840.1 - 0.0061 16.2 20.8 0.012 15.2 20.8 1.4 1 0 0 1 1 1 1 Spt20 family SPATIAL PF15256.6 PSC75840.1 - 0.058 13.7 2.2 0.094 13.0 2.2 1.3 1 0 0 1 1 1 0 SPATIAL DUF4834 PF16118.5 PSC75840.1 - 0.33 12.0 6.6 0.97 10.4 6.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) CDC45 PF02724.14 PSC75840.1 - 3.8 5.7 6.2 4.6 5.4 6.2 1.1 1 0 0 1 1 1 0 CDC45-like protein eIF-3_zeta PF05091.12 PSC75840.1 - 9.6 5.1 9.7 15 4.5 9.7 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) PP2C PF00481.21 PSC75841.1 - 3.4e-27 95.7 0.0 5.6e-27 95.0 0.0 1.2 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 PSC75841.1 - 1e-06 28.6 0.7 2.8e-06 27.1 0.7 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 PSC75841.1 - 3.3e-05 23.9 0.1 0.00096 19.1 0.0 2.6 3 0 0 3 3 3 1 Stage II sporulation protein E (SpoIIE) DUF212 PF02681.14 PSC75842.1 - 3.3e-33 114.6 0.4 3.7e-33 114.4 0.4 1.0 1 0 0 1 1 1 1 Divergent PAP2 family PAP2 PF01569.21 PSC75842.1 - 0.0022 17.8 2.5 0.67 9.7 0.1 2.1 2 0 0 2 2 2 2 PAP2 superfamily Melibiase_2 PF16499.5 PSC75843.1 - 9.3e-64 215.3 0.6 1.2e-63 214.9 0.6 1.2 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 PSC75843.1 - 4.8e-14 52.2 0.0 1.4e-13 50.7 0.0 1.8 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase PF02065.18 PSC75843.1 - 0.00017 20.7 0.0 0.00033 19.7 0.0 1.4 1 1 0 1 1 1 1 Melibiase Jiv90 PF14901.6 PSC75844.1 - 1.8e-15 56.8 2.4 4.9e-15 55.4 2.4 1.7 1 0 0 1 1 1 1 Cleavage inducing molecular chaperone DnaJ PF00226.31 PSC75844.1 - 3.4e-15 55.9 0.0 6.5e-15 55.0 0.0 1.5 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 PSC75844.1 - 0.00059 19.8 3.1 0.0009 19.2 0.6 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat Pex14_N PF04695.13 PSC75844.1 - 0.0024 18.5 13.8 0.0024 18.5 13.8 2.6 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region TPR_14 PF13428.6 PSC75844.1 - 0.01 16.6 4.1 0.01 16.6 4.1 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PIH1_CS PF18201.1 PSC75844.1 - 0.022 15.1 0.0 0.043 14.2 0.0 1.4 1 0 0 1 1 1 0 PIH1 CS-like domain TPR_11 PF13414.6 PSC75844.1 - 0.027 14.1 0.0 0.072 12.8 0.0 1.7 1 0 0 1 1 1 0 TPR repeat PBP1_TM PF14812.6 PSC75844.1 - 4.6 7.7 6.1 11 6.4 6.1 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4698 PF15769.5 PSC75844.1 - 9.1 5.2 11.0 18 4.3 11.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) Peptidase_S9 PF00326.21 PSC75845.1 - 0.044 13.3 0.0 0.053 13.0 0.0 1.1 1 0 0 1 1 1 0 Prolyl oligopeptidase family Cnd2 PF05786.14 PSC75846.1 - 2.3e-115 387.1 0.0 4.9e-115 386.0 0.0 1.5 1 1 0 1 1 1 1 Condensin complex subunit 2 CNDH2_N PF06278.11 PSC75846.1 - 0.02 15.1 0.0 0.043 14.0 0.0 1.5 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Ank_5 PF13857.6 PSC75847.1 - 3.2e-20 71.9 14.3 0.00055 20.2 0.1 6.9 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_2 PF12796.7 PSC75847.1 - 6.2e-20 71.6 2.4 0.00035 21.1 0.2 5.8 3 1 3 6 6 6 5 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PSC75847.1 - 1.3e-14 52.9 11.1 0.037 14.6 0.0 7.9 7 0 0 7 7 7 4 Ankyrin repeat Ank_4 PF13637.6 PSC75847.1 - 6.6e-14 52.1 12.2 0.03 14.9 0.1 7.4 6 1 1 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 PSC75847.1 - 0.0076 16.7 26.2 1 9.9 0.1 7.8 7 2 0 7 7 7 2 Ankyrin repeat Rnk_N PF14760.6 PSC75847.1 - 7.1 7.2 6.5 46 4.6 0.7 3.1 2 0 0 2 2 2 0 Rnk N-terminus Copine PF07002.16 PSC75848.1 - 1.9e-70 236.7 0.0 2.6e-70 236.3 0.0 1.1 1 0 0 1 1 1 1 Copine C2 PF00168.30 PSC75848.1 - 4.7e-25 87.9 0.0 6.1e-14 52.2 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 PSC75848.1 - 0.00037 20.7 0.0 0.00063 19.9 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus TPR_2 PF07719.17 PSC75849.1 - 8.6e-17 59.8 18.7 0.00018 21.4 0.0 7.8 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_1 PF00515.28 PSC75849.1 - 4e-14 51.7 6.8 0.00027 20.6 0.0 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_16 PF13432.6 PSC75849.1 - 1.8e-10 41.3 3.8 1.7e-08 35.0 0.8 10.2 9 4 3 12 12 7 3 Tetratricopeptide repeat TPR_9 PF13371.6 PSC75849.1 - 5.7e-10 39.2 5.6 7.3e-05 22.8 0.1 7.8 6 1 2 8 8 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 PSC75849.1 - 6.9e-09 35.5 6.7 0.17 12.3 0.0 6.1 6 1 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 PSC75849.1 - 2.2e-07 31.3 0.1 2.9e-06 27.7 0.1 9.8 8 2 2 10 10 7 3 Tetratricopeptide repeat TPR_7 PF13176.6 PSC75849.1 - 4.1e-07 29.6 7.0 2.1 8.6 0.0 7.9 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.6 PSC75849.1 - 1.1e-05 25.3 0.1 0.029 14.6 0.0 5.0 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 PSC75849.1 - 2.6e-05 23.8 7.4 0.045 13.4 0.0 5.4 5 1 1 6 6 6 2 TPR repeat ANAPC3 PF12895.7 PSC75849.1 - 0.00018 21.7 2.3 0.0016 18.6 0.4 5.1 5 1 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 PSC75849.1 - 0.0008 18.7 20.0 0.0046 16.2 0.8 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 PSC75849.1 - 0.029 15.2 0.1 0.28 12.1 0.2 12.5 11 2 4 15 15 12 0 Tetratricopeptide repeat ANAPC5 PF12862.7 PSC75849.1 - 0.05 13.7 0.0 0.05 13.7 0.0 3.4 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 5 TPR_6 PF13174.6 PSC75849.1 - 2.4 9.0 0.0 2.4 9.0 0.0 6.3 9 0 0 9 9 3 0 Tetratricopeptide repeat MatE PF01554.18 PSC75850.1 - 4.7e-56 188.9 30.2 1.3e-28 99.7 12.4 2.3 2 0 0 2 2 2 2 MatE HopA1 PF17914.1 PSC75850.1 - 0.019 14.7 0.1 0.035 13.9 0.1 1.3 1 0 0 1 1 1 0 HopA1 effector protein family Ank_5 PF13857.6 PSC75852.1 - 1.5e-09 37.9 0.1 8e-08 32.4 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PSC75852.1 - 1.1e-07 32.4 0.0 1.4e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC75852.1 - 1.7e-06 28.4 0.0 4.4e-06 27.1 0.0 1.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC75852.1 - 3.8e-05 23.8 0.3 0.0014 19.0 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 PSC75852.1 - 7.1e-05 23.1 0.8 0.0064 16.9 0.2 2.3 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 PSC75853.1 - 3.9e-26 91.4 6.5 1.1e-06 29.1 0.2 5.9 5 1 2 7 7 7 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC75853.1 - 7.5e-22 77.4 2.0 0.00023 21.7 0.1 7.5 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC75853.1 - 3.3e-16 59.1 7.6 5.6e-06 26.5 0.0 6.5 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC75853.1 - 1.7e-12 46.3 15.6 0.058 14.0 0.0 9.9 10 0 0 10 10 10 4 Ankyrin repeat Ank PF00023.30 PSC75853.1 - 2.7e-06 27.6 20.1 0.073 13.5 0.0 8.1 8 0 0 8 8 8 2 Ankyrin repeat zf-MYND PF01753.18 PSC75853.1 - 0.00015 21.8 11.3 0.00036 20.5 11.3 1.7 1 0 0 1 1 1 1 MYND finger PHO4 PF01384.20 PSC75854.1 - 3.5e-118 394.5 15.0 4.5e-118 394.2 15.0 1.1 1 0 0 1 1 1 1 Phosphate transporter family Tim17 PF02466.19 PSC75854.1 - 5.9 7.3 8.7 3.4 8.1 0.1 3.8 3 1 1 4 4 4 0 Tim17/Tim22/Tim23/Pmp24 family AAA PF00004.29 PSC75856.1 - 4.9e-43 146.7 0.0 1.1e-42 145.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 PSC75856.1 - 1.8e-38 132.3 0.3 3.2e-38 131.5 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M41 AAA_lid_3 PF17862.1 PSC75856.1 - 1.5e-10 40.7 0.2 3.3e-10 39.6 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 PSC75856.1 - 1.3e-07 31.7 0.1 5.2e-07 29.7 0.0 2.1 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) FtsH_ext PF06480.15 PSC75856.1 - 9.3e-06 26.0 0.0 6.4e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 FtsH Extracellular AAA_2 PF07724.14 PSC75856.1 - 1.3e-05 25.4 0.0 2.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 PSC75856.1 - 2.2e-05 24.9 1.0 0.00045 20.6 0.7 3.0 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 PSC75856.1 - 8.6e-05 22.3 0.0 0.00026 20.8 0.0 1.9 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 PSC75856.1 - 9.3e-05 21.8 0.0 0.00015 21.1 0.0 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_22 PF13401.6 PSC75856.1 - 0.00032 21.0 0.1 0.025 14.9 0.0 2.9 2 1 1 3 3 3 1 AAA domain AAA_33 PF13671.6 PSC75856.1 - 0.0039 17.4 0.0 0.01 16.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.6 PSC75856.1 - 0.0072 15.9 0.7 1.8 8.1 0.2 3.6 3 1 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 PSC75856.1 - 0.0077 16.0 0.0 0.017 14.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 PSC75856.1 - 0.0092 16.0 0.0 0.48 10.5 0.0 2.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 PSC75856.1 - 0.017 14.5 0.3 0.04 13.3 0.2 1.7 1 1 1 2 2 2 0 Magnesium chelatase, subunit ChlI ATPase PF06745.13 PSC75856.1 - 0.04 13.3 0.0 1.3 8.4 0.0 2.4 2 0 0 2 2 2 0 KaiC AAA_28 PF13521.6 PSC75856.1 - 0.048 13.9 0.0 0.26 11.5 0.0 2.1 1 1 1 2 2 2 0 AAA domain DUF815 PF05673.13 PSC75856.1 - 0.061 12.5 0.0 0.33 10.1 0.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 PSC75856.1 - 0.13 11.7 0.0 0.35 10.4 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 PSC75856.1 - 0.14 11.9 0.0 0.34 10.6 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain PhoH PF02562.16 PSC75856.1 - 0.18 11.3 0.1 0.43 10.0 0.1 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_18 PF13238.6 PSC75856.1 - 0.18 12.4 0.0 0.38 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain WD40 PF00400.32 PSC75857.1 - 9.7e-23 80.0 7.0 6.2e-08 33.2 0.0 5.8 6 1 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC75857.1 - 1.9e-09 37.7 0.0 7.2e-05 23.0 0.0 3.9 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PSC75857.1 - 2.9e-09 36.3 0.0 0.00058 18.9 0.0 3.3 3 1 0 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 PSC75857.1 - 0.018 14.9 0.0 2.5 8.1 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat DPPIV_N PF00930.21 PSC75857.1 - 0.13 11.0 0.0 0.24 10.1 0.0 1.4 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region rve PF00665.26 PSC75858.1 - 8.4e-19 67.9 0.0 1.8e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC75858.1 - 0.0066 16.2 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain Mg_trans_NIPA PF05653.14 PSC75859.1 - 3.9e-07 29.5 5.8 0.0015 17.7 0.4 2.1 2 0 0 2 2 2 2 Magnesium transporter NIPA DUF4064 PF13273.6 PSC75859.1 - 0.12 12.6 2.5 2 8.8 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Hep_59 PF07052.11 PSC75860.1 - 9.7e-20 71.3 1.4 9.7e-20 71.3 1.4 2.4 3 0 0 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 FapA PF03961.13 PSC75860.1 - 0.56 8.7 3.1 0.51 8.9 0.1 1.9 2 0 0 2 2 2 0 Flagellar Assembly Protein A Ank_2 PF12796.7 PSC75861.1 - 2.7e-15 56.7 0.1 2.9e-08 34.2 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC75861.1 - 1.4e-14 54.0 0.3 1.6e-10 41.0 0.1 2.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC75861.1 - 3e-12 46.8 0.1 1.6e-08 34.9 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 PSC75861.1 - 3.4e-11 42.8 15.4 5.5e-11 42.1 15.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Ank PF00023.30 PSC75861.1 - 6.1e-11 42.2 0.0 0.066 13.7 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 PSC75861.1 - 1.4e-09 37.4 0.0 0.034 14.7 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Prok-RING_4 PF14447.6 PSC75861.1 - 0.00057 19.7 13.7 0.001 18.9 13.7 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PSC75861.1 - 0.21 11.5 15.1 0.48 10.4 15.1 1.6 1 0 0 1 1 1 0 zinc-RING finger domain NAM-associated PF14303.6 PSC75861.1 - 6.3 7.5 8.5 20 5.8 8.5 1.9 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain RINGv PF12906.7 PSC75862.1 - 5.4e-05 23.2 16.5 8.4e-05 22.6 16.5 1.3 1 0 0 1 1 1 1 RING-variant domain 3-PAP PF12578.8 PSC75862.1 - 0.017 14.8 0.0 0.026 14.3 0.0 1.3 1 0 0 1 1 1 0 Myotubularin-associated protein FANCL_C PF11793.8 PSC75862.1 - 0.41 10.9 8.4 0.7 10.1 8.4 1.4 1 0 0 1 1 1 0 FANCL C-terminal domain GTP_EFTU PF00009.27 PSC75863.1 - 1.2e-33 116.3 1.2 2.4e-32 112.1 1.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 PSC75863.1 - 4.6e-26 91.0 0.1 8.7e-26 90.1 0.1 1.4 1 0 0 1 1 1 1 Translation-initiation factor 2 CPBP PF02517.16 PSC75863.1 - 1.2e-17 64.0 0.6 2.7e-17 62.9 0.6 1.5 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease MMR_HSR1 PF01926.23 PSC75863.1 - 1.5e-08 34.7 0.0 2.8e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase IF2_N PF04760.15 PSC75863.1 - 0.00049 19.8 0.0 0.001 18.8 0.0 1.5 1 0 0 1 1 1 1 Translation initiation factor IF-2, N-terminal region FeoB_N PF02421.18 PSC75863.1 - 0.0014 18.2 0.0 0.0045 16.5 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.9 PSC75863.1 - 0.0033 17.2 0.0 0.0096 15.7 0.0 1.7 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation GTP_EFTU_D2 PF03144.25 PSC75863.1 - 0.0047 17.3 7.3 0.2 12.0 0.2 3.3 3 0 0 3 3 3 2 Elongation factor Tu domain 2 RsgA_GTPase PF03193.16 PSC75863.1 - 0.01 15.7 0.1 0.68 9.8 0.0 2.3 1 1 1 2 2 2 0 RsgA GTPase Hydrolase PF00702.26 PSC75863.1 - 0.029 14.6 2.3 0.047 14.0 0.6 1.9 1 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Ras PF00071.22 PSC75863.1 - 0.05 13.2 0.0 0.079 12.6 0.0 1.3 1 0 0 1 1 1 0 Ras family PDZ_2 PF13180.6 PSC75863.1 - 0.069 13.5 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 PDZ domain SRPRB PF09439.10 PSC75863.1 - 0.17 11.3 0.1 0.49 9.8 0.1 1.7 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit MRP-L27 PF09809.9 PSC75865.1 - 4.5e-16 58.7 0.2 5.1e-16 58.5 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 TFIIA PF03153.13 PSC75866.1 - 0.00039 20.5 6.6 0.00044 20.4 6.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 PSC75866.1 - 0.11 11.2 1.8 0.1 11.3 1.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SOG2 PF10428.9 PSC75866.1 - 0.11 11.7 8.6 0.15 11.3 8.6 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein DUF3682 PF12446.8 PSC75866.1 - 0.17 12.4 19.4 0.22 12.0 18.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3682) AIF_C PF14721.6 PSC75866.1 - 0.19 12.1 3.0 0.34 11.3 3.0 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF2722 PF10846.8 PSC75866.1 - 0.25 10.3 10.0 0.31 9.9 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CPSF100_C PF13299.6 PSC75866.1 - 0.26 11.5 5.7 0.27 11.4 3.7 2.0 3 0 0 3 3 3 0 Cleavage and polyadenylation factor 2 C-terminal Herpes_DNAp_acc PF04929.12 PSC75866.1 - 0.35 9.8 4.6 0.45 9.4 4.6 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor DUF5421 PF17458.2 PSC75866.1 - 0.42 10.0 4.9 2.4 7.5 4.1 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5421) Spt20 PF12090.8 PSC75866.1 - 0.43 10.1 15.4 0.63 9.6 15.4 1.1 1 0 0 1 1 1 0 Spt20 family Presenilin PF01080.17 PSC75866.1 - 0.54 9.0 2.6 0.65 8.7 2.6 1.1 1 0 0 1 1 1 0 Presenilin CDC27 PF09507.10 PSC75866.1 - 0.83 9.0 9.2 1 8.7 9.2 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF4834 PF16118.5 PSC75866.1 - 1.2 10.1 7.1 2 9.4 7.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Roughex PF06020.11 PSC75866.1 - 1.2 8.1 8.1 1.7 7.6 8.1 1.2 1 0 0 1 1 1 0 Drosophila roughex protein DUF1180 PF06679.12 PSC75866.1 - 7.3 7.0 12.5 12 6.3 12.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DNA_methylase PF00145.17 PSC75867.1 - 2.2e-46 158.8 0.0 4.4e-40 138.0 0.0 2.5 2 0 0 2 2 2 2 C-5 cytosine-specific DNA methylase DNMT1-RFD PF12047.8 PSC75867.1 - 3.4e-35 121.2 0.0 5e-20 72.0 0.0 2.8 2 1 0 2 2 2 2 Cytosine specific DNA methyltransferase replication foci domain BAH PF01426.18 PSC75867.1 - 4.4e-17 62.1 0.0 3.3e-09 36.6 0.0 2.7 2 0 0 2 2 2 2 BAH domain DUF2656 PF10847.8 PSC75867.1 - 0.15 12.1 0.3 0.38 10.9 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2656) ABC_tran PF00005.27 PSC75868.1 - 1.7e-33 116.0 0.0 2.9e-33 115.3 0.0 1.4 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 PSC75868.1 - 1.4e-30 106.8 9.2 1.9e-30 106.4 9.2 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 PSC75868.1 - 8.7e-09 35.1 0.0 4.7e-06 26.2 0.0 2.2 1 1 1 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PSC75868.1 - 7.4e-05 23.2 0.6 0.00033 21.1 0.6 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 PSC75868.1 - 0.00064 19.4 0.3 0.0016 18.2 0.3 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 PSC75868.1 - 0.0009 18.9 0.7 0.24 10.9 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 PSC75868.1 - 0.00094 19.5 0.0 0.0046 17.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain ABC_ATPase PF09818.9 PSC75868.1 - 0.0016 17.3 3.6 0.16 10.7 0.0 3.0 3 0 0 3 3 3 2 Predicted ATPase of the ABC class Zeta_toxin PF06414.12 PSC75868.1 - 0.0036 16.6 0.1 0.014 14.7 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin APS_kinase PF01583.20 PSC75868.1 - 0.0091 15.9 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase RsgA_GTPase PF03193.16 PSC75868.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_21 PF13304.6 PSC75868.1 - 0.017 14.9 0.1 0.24 11.2 0.0 2.1 1 1 1 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_30 PF13604.6 PSC75868.1 - 0.021 14.6 3.5 0.059 13.1 0.9 2.8 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 PSC75868.1 - 0.024 14.8 0.0 0.075 13.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain DUF87 PF01935.17 PSC75868.1 - 0.025 14.7 0.2 0.042 13.9 0.2 1.3 1 0 0 1 1 1 0 Helicase HerA, central domain AAA_23 PF13476.6 PSC75868.1 - 0.33 11.4 0.2 0.53 10.7 0.2 1.2 1 0 0 1 1 1 0 AAA domain Ribosomal_L22 PF00237.19 PSC75869.1 - 3.6e-28 97.8 0.2 5.3e-28 97.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e Cuticle_3 PF11018.8 PSC75869.1 - 1.6 8.9 9.2 6.4 6.9 7.2 2.0 2 0 0 2 2 2 0 Pupal cuticle protein C1 Fer2 PF00111.27 PSC75870.1 - 8.8e-11 41.6 0.8 1.8e-10 40.6 0.9 1.5 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain UbiA PF01040.18 PSC75871.1 - 8.4e-57 192.3 19.5 1.1e-56 192.0 19.5 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family AP2 PF00847.20 PSC75872.1 - 0.0099 16.1 0.1 0.03 14.6 0.1 1.8 1 0 0 1 1 1 1 AP2 domain Glyco_hydro_cc PF11790.8 PSC75873.1 - 4e-35 121.5 0.0 7.6e-32 110.8 0.0 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase catalytic core Exo_endo_phos PF03372.23 PSC75873.1 - 1.6e-14 54.0 0.2 3.1e-14 53.1 0.2 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family SATase_N PF06426.14 PSC75874.1 - 5.9e-39 132.7 0.6 1.1e-38 131.8 0.6 1.5 1 0 0 1 1 1 1 Serine acetyltransferase, N-terminal Hexapep PF00132.24 PSC75874.1 - 2.1e-06 27.2 11.4 1.6e-05 24.4 3.5 2.5 2 0 0 2 2 2 2 Bacterial transferase hexapeptide (six repeats) Med15 PF09606.10 PSC75874.1 - 0.019 13.7 18.3 0.026 13.2 18.3 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SARAF PF06682.12 PSC75874.1 - 0.025 14.2 4.6 0.046 13.4 4.6 1.3 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF5326 PF17260.2 PSC75874.1 - 0.037 14.2 0.1 0.086 13.0 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5326) Pex14_N PF04695.13 PSC75874.1 - 0.063 13.9 8.4 0.18 12.4 6.4 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Trypan_PARP PF05887.11 PSC75874.1 - 0.069 13.1 0.7 0.14 12.1 0.1 1.8 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) TFIIA PF03153.13 PSC75874.1 - 0.1 12.5 9.3 0.2 11.6 9.3 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF5127 PF17168.4 PSC75874.1 - 0.13 12.0 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5127) Suf PF05843.14 PSC75874.1 - 5.8 6.8 5.3 9.9 6.0 5.3 1.3 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Glycolytic PF00274.19 PSC75875.1 - 5.7e-124 413.4 0.0 6.6e-124 413.2 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I POP1 PF06978.11 PSC75877.1 - 2.9e-14 53.6 0.0 5.6e-14 52.6 0.0 1.5 1 0 0 1 1 1 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 PSC75877.1 - 6e-14 52.1 0.7 6e-14 52.1 0.7 1.9 2 0 0 2 2 2 1 POPLD (NUC188) domain Polysacc_deac_1 PF01522.21 PSC75877.1 - 2.3e-08 34.0 0.1 1.1e-06 28.6 0.0 2.7 2 0 0 2 2 2 1 Polysaccharide deacetylase Roughex PF06020.11 PSC75877.1 - 2.1 7.4 4.8 4.5 6.3 4.8 1.5 1 0 0 1 1 1 0 Drosophila roughex protein CRS1_YhbY PF01985.21 PSC75879.1 - 3.5e-14 52.7 0.0 6.1e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 CRS1 / YhbY (CRM) domain FoP_duplication PF13865.6 PSC75879.1 - 3.8 8.1 6.4 0.47 11.0 0.2 2.5 2 1 1 3 3 3 0 C-terminal duplication domain of Friend of PRMT1 DUF220 PF02713.14 PSC75881.1 - 0.0025 17.9 0.0 0.0051 16.9 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function DUF220 Spt20 PF12090.8 PSC75881.1 - 0.053 13.1 3.0 0.072 12.7 3.0 1.2 1 0 0 1 1 1 0 Spt20 family Polyketide_cyc PF03364.20 PSC75881.1 - 0.14 12.3 0.0 0.51 10.6 0.0 1.9 1 1 1 2 2 2 0 Polyketide cyclase / dehydrase and lipid transport Beta_helix PF13229.6 PSC75883.1 - 2.5e-15 56.7 20.0 4.6e-08 33.1 3.9 4.7 3 2 0 3 3 3 2 Right handed beta helix region TFIIA PF03153.13 PSC75883.1 - 3.2e-05 24.1 43.9 5.2e-05 23.4 43.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 PSC75883.1 - 0.04 14.1 12.5 0.065 13.4 12.5 1.2 1 0 0 1 1 1 0 DDHD domain zf-like PF04071.12 PSC75883.1 - 0.057 13.3 1.8 21 5.1 0.0 3.5 3 0 0 3 3 3 0 Cysteine-rich small domain eIF-3_zeta PF05091.12 PSC75883.1 - 0.092 11.7 21.8 0.14 11.1 21.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF572 PF04502.13 PSC75883.1 - 0.1 12.2 11.3 0.15 11.7 11.3 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Pex14_N PF04695.13 PSC75883.1 - 0.11 13.2 30.1 0.24 12.1 30.1 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EPL1 PF10513.9 PSC75883.1 - 0.16 12.4 16.7 0.24 11.7 16.7 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF4820 PF16091.5 PSC75883.1 - 0.19 11.1 12.0 0.45 9.8 12.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) SpoIIP PF07454.11 PSC75883.1 - 0.2 11.1 18.3 0.3 10.5 18.3 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Presenilin PF01080.17 PSC75883.1 - 0.2 10.4 20.6 0.31 9.8 20.6 1.1 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 PSC75883.1 - 0.24 10.4 14.4 0.38 9.7 14.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF5427 PF10310.9 PSC75883.1 - 0.25 10.2 20.0 0.38 9.7 20.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) FAM60A PF15396.6 PSC75883.1 - 0.5 10.3 10.0 0.92 9.5 10.0 1.3 1 0 0 1 1 1 0 Protein Family FAM60A DUF4637 PF15470.6 PSC75883.1 - 0.53 10.0 10.8 0.92 9.2 10.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Lin-8 PF03353.15 PSC75883.1 - 0.57 9.7 19.6 0.83 9.2 19.6 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist RR_TM4-6 PF06459.12 PSC75883.1 - 0.71 9.6 17.6 1.1 9.1 17.6 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4407 PF14362.6 PSC75883.1 - 0.76 9.1 22.2 1.3 8.3 22.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Membralin PF09746.9 PSC75883.1 - 0.94 8.4 8.1 1.4 7.9 8.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF3295 PF11702.8 PSC75883.1 - 0.99 8.7 17.6 1.4 8.2 17.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) CCSAP PF15748.5 PSC75883.1 - 0.99 9.5 20.0 1.5 8.9 20.0 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF2828 PF11443.8 PSC75883.1 - 1.1 7.2 16.7 1.6 6.8 16.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) Endostatin PF06482.11 PSC75883.1 - 1.3 8.4 17.8 2.1 7.7 17.8 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin CPSF100_C PF13299.6 PSC75883.1 - 1.7 8.8 14.3 2.8 8.1 14.3 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Bul1_N PF04425.12 PSC75883.1 - 1.8 7.3 14.5 2.5 6.7 14.5 1.1 1 0 0 1 1 1 0 Bul1 N terminus Neur_chan_memb PF02932.16 PSC75883.1 - 1.9 8.5 14.1 2.9 7.9 14.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PIG-S PF10510.9 PSC75883.1 - 2 7.1 13.0 2.9 6.6 13.0 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein BORG_CEP PF14957.6 PSC75883.1 - 2.9 9.1 11.8 5.3 8.2 11.8 1.3 1 0 0 1 1 1 0 Cdc42 effector NPR3 PF03666.13 PSC75883.1 - 3.2 6.4 15.6 4.7 5.9 15.6 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF702 PF05142.12 PSC75883.1 - 4.2 7.8 16.4 9.6 6.7 16.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Eapp_C PF10238.9 PSC75883.1 - 5.2 7.1 17.8 11 6.1 17.8 1.5 1 0 0 1 1 1 0 E2F-associated phosphoprotein CDC45 PF02724.14 PSC75883.1 - 6.5 4.9 15.1 9.2 4.4 15.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Hid1 PF12722.7 PSC75883.1 - 7.4 4.6 18.1 11 4.0 18.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein GREB1 PF15782.5 PSC75883.1 - 7.5 3.5 19.0 9.9 3.1 19.0 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Pkinase PF00069.25 PSC75884.1 - 6.9e-16 58.4 0.0 2.2e-15 56.7 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 PSC75884.1 - 1.9e-07 30.2 0.0 3.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 PSC75884.1 - 0.00016 21.0 0.0 0.00038 19.8 0.0 1.5 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PSC75884.1 - 0.00032 20.1 0.0 0.00059 19.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2076 PF09849.9 PSC75884.1 - 0.00052 20.1 7.2 0.0012 19.0 7.2 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Spt20 PF12090.8 PSC75884.1 - 1.1 8.8 6.7 1.7 8.2 6.7 1.2 1 0 0 1 1 1 0 Spt20 family Pkinase PF00069.25 PSC75885.1 - 1.6e-16 60.5 0.0 2.9e-16 59.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 PSC75885.1 - 1.9e-07 30.2 0.0 3.2e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Pkinase_Tyr PF07714.17 PSC75885.1 - 3.1e-05 23.4 0.0 4.8e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 PSC75885.1 - 0.00032 20.1 0.0 0.00059 19.2 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2076 PF09849.9 PSC75885.1 - 0.00052 20.1 7.2 0.0011 19.0 7.2 1.5 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Spt20 PF12090.8 PSC75885.1 - 1.1 8.8 6.7 1.7 8.2 6.7 1.2 1 0 0 1 1 1 0 Spt20 family TPR_14 PF13428.6 PSC75887.1 - 4.2 8.5 6.7 1.3 10.0 0.2 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat Aldo_ket_red PF00248.21 PSC75888.1 - 1.6e-60 204.8 0.0 1.8e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Aldo_ket_red PF00248.21 PSC75889.1 - 1.6e-60 204.8 0.0 1.8e-60 204.6 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Pro_isomerase PF00160.21 PSC75890.1 - 2e-51 174.4 0.0 2.6e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SAM_1 PF00536.30 PSC75890.1 - 0.013 15.9 0.0 0.027 14.9 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 PSC75890.1 - 0.026 14.6 0.0 0.058 13.5 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Ank_5 PF13857.6 PSC75892.1 - 0.00023 21.4 0.3 0.00042 20.5 0.3 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Methyltransf_25 PF13649.6 PSC75892.1 - 0.0014 19.3 0.0 0.0028 18.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ank_2 PF12796.7 PSC75892.1 - 0.0016 19.0 0.0 0.0028 18.2 0.0 1.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Methyltransf_24 PF13578.6 PSC75892.1 - 0.0098 16.9 0.0 0.03 15.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Ank_3 PF13606.6 PSC75892.1 - 0.12 13.0 0.0 18 6.3 0.1 2.8 2 0 0 2 2 2 0 Ankyrin repeat Ank_4 PF13637.6 PSC75892.1 - 0.13 12.9 0.0 0.28 11.8 0.0 1.6 1 0 0 1 1 1 0 Ankyrin repeats (many copies) YTH PF04146.15 PSC75893.1 - 1.2e-25 90.4 0.0 7.7e-24 84.5 0.0 2.3 1 1 0 1 1 1 1 YT521-B-like domain TraC PF07820.12 PSC75893.1 - 3 8.2 5.3 0.91 9.9 0.3 2.4 2 0 0 2 2 2 0 TraC-like protein YTH PF04146.15 PSC75894.1 - 1.2e-25 90.4 0.0 7.7e-24 84.5 0.0 2.3 1 1 0 1 1 1 1 YT521-B-like domain TraC PF07820.12 PSC75894.1 - 3 8.2 5.3 0.91 9.9 0.3 2.4 2 0 0 2 2 2 0 TraC-like protein Glyco_hydro_114 PF03537.13 PSC75895.1 - 3.1e-61 206.6 0.0 4.7e-61 206.1 0.0 1.3 1 0 0 1 1 1 1 Glycoside-hydrolase family GH114 Aminotran_1_2 PF00155.21 PSC75895.1 - 8.8e-22 77.8 0.0 1.4e-21 77.1 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 PSC75895.1 - 8.3e-11 41.3 0.0 1.3e-10 40.7 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase MFS_3 PF05977.13 PSC75896.1 - 5.4e-17 61.4 13.9 5.4e-17 61.4 13.9 2.4 2 0 0 2 2 2 1 Transmembrane secretion effector MFS_1 PF07690.16 PSC75896.1 - 2.8e-14 52.8 50.4 5.4e-14 51.9 10.3 3.0 2 1 0 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.7 PSC75896.1 - 2.3e-05 23.5 0.0 0.12 11.2 0.0 2.6 1 1 0 2 2 2 2 MFS_1 like family DUF1634 PF07843.11 PSC75896.1 - 0.015 15.4 0.9 0.085 12.9 0.9 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1634) DUF4491 PF14898.6 PSC75896.1 - 0.074 13.5 0.1 0.35 11.4 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4491) zf-TAZ PF02135.16 PSC75897.1 - 0.0068 16.8 7.3 0.02 15.3 7.1 1.9 1 1 0 1 1 1 1 TAZ zinc finger Nefa_Nip30_N PF10187.9 PSC75898.1 - 2.4e-14 53.5 6.8 3.6e-14 53.0 6.0 1.7 1 1 1 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Metallophos PF00149.28 PSC75899.1 - 1.1e-28 101.2 0.1 1.5e-28 100.7 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase TFIIA PF03153.13 PSC75899.1 - 0.0081 16.2 12.2 0.011 15.8 12.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit eIF-3_zeta PF05091.12 PSC75899.1 - 0.88 8.5 4.6 1.2 8.1 4.6 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF2722 PF10846.8 PSC75899.1 - 2 7.3 12.6 3.4 6.5 12.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Lin-8 PF03353.15 PSC75899.1 - 2.3 7.7 7.0 3.3 7.2 7.0 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Roughex PF06020.11 PSC75899.1 - 4.3 6.3 14.3 6.2 5.8 14.3 1.2 1 0 0 1 1 1 0 Drosophila roughex protein CDP-OH_P_transf PF01066.21 PSC75900.1 - 0.044 14.5 0.2 0.061 14.1 0.2 1.3 1 0 0 1 1 1 0 CDP-alcohol phosphatidyltransferase RecR PF02132.15 PSC75900.1 - 0.19 11.3 6.7 0.3 10.7 6.7 1.5 1 1 0 1 1 1 0 RecR protein DnaJ PF00226.31 PSC75901.1 - 2.3e-10 40.4 0.0 3.7e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain CLP1_P PF16575.5 PSC75902.1 - 8.1e-37 126.8 0.0 6.2e-27 94.6 0.0 2.2 2 0 0 2 2 2 2 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_33 PF13671.6 PSC75902.1 - 0.046 13.9 0.0 0.091 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain ParA PF10609.9 PSC75902.1 - 0.078 12.4 0.0 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 NUBPL iron-transfer P-loop NTPase RNA_helicase PF00910.22 PSC75902.1 - 0.15 12.4 0.0 0.28 11.6 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.6 PSC75902.1 - 0.18 12.1 0.0 0.37 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 PSC75902.1 - 0.18 12.3 0.0 0.29 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain Got1 PF04178.12 PSC75903.1 - 4.6e-36 123.7 15.2 5.7e-36 123.4 15.2 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF5345 PF17280.2 PSC75903.1 - 0.068 13.1 2.1 7.3 6.7 1.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5345) DUF3487 PF11990.8 PSC75903.1 - 3.3 7.6 6.1 11 6.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) GPI2 PF06432.11 PSC75905.1 - 8.8e-65 218.9 0.4 1e-64 218.7 0.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase CLTH PF10607.9 PSC75906.1 - 1.1e-34 119.4 0.0 1.5e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain IHABP4_N PF16174.5 PSC75906.1 - 0.13 12.8 1.0 0.23 12.1 0.1 1.7 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal TPT PF03151.16 PSC75907.1 - 2.8e-12 46.6 14.8 3.8e-12 46.2 14.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PSC75907.1 - 9.7e-08 32.3 27.2 0.00075 19.7 11.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family Aa_trans PF01490.18 PSC75909.1 - 7.1e-36 123.8 10.9 8.9e-36 123.5 10.9 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PsbP PF01789.16 PSC75910.1 - 2.8e-15 56.8 0.0 4.1e-15 56.3 0.0 1.2 1 0 0 1 1 1 1 PsbP PsbQ PF05757.11 PSC75910.1 - 0.0091 15.7 1.0 0.015 15.0 1.0 1.4 1 0 0 1 1 1 1 Oxygen evolving enhancer protein 3 (PsbQ) Laminin_G_3 PF13385.6 PSC75911.1 - 0.0064 16.7 0.6 0.0069 16.5 0.6 1.2 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Pkinase PF00069.25 PSC75912.1 - 5.7e-30 104.6 0.0 1.4e-29 103.2 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC75912.1 - 8.4e-29 100.6 0.0 2.3e-28 99.2 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase 5_nucleotid_C PF02872.18 PSC75912.1 - 7.5e-23 81.5 0.0 1.3e-22 80.7 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 PSC75912.1 - 3.4e-10 40.8 0.0 8.5e-10 39.5 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase LRRNT_2 PF08263.12 PSC75912.1 - 9.8e-07 29.0 0.1 2.6e-06 27.6 0.1 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain PGA_cap PF09587.10 PSC75912.1 - 0.013 15.0 0.8 0.07 12.6 0.8 2.0 1 1 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Pkinase PF00069.25 PSC75913.1 - 5.3e-30 104.7 0.0 1.4e-29 103.3 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC75913.1 - 7.7e-29 100.7 0.0 2.2e-28 99.3 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase 5_nucleotid_C PF02872.18 PSC75913.1 - 7e-23 81.6 0.0 1.2e-22 80.8 0.0 1.4 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 PSC75913.1 - 3.1e-10 40.9 0.0 7.9e-10 39.6 0.0 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase LRRNT_2 PF08263.12 PSC75913.1 - 9.7e-07 29.0 0.1 2.5e-06 27.7 0.1 1.8 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain PGA_cap PF09587.10 PSC75913.1 - 0.012 15.1 0.8 0.068 12.6 0.8 2.0 1 1 0 1 1 1 0 Bacterial capsule synthesis protein PGA_cap Pirin PF02678.16 PSC75914.1 - 1e-27 96.3 0.0 1.8e-27 95.5 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C_2 PF17954.1 PSC75914.1 - 3.2e-10 40.0 0.0 7.5e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 Quercetinase C-terminal cupin domain Cupin_2 PF07883.11 PSC75914.1 - 6.5e-08 32.2 0.1 2.4e-06 27.2 0.0 2.6 3 0 0 3 3 3 1 Cupin domain Pirin_C PF05726.13 PSC75914.1 - 0.0024 18.2 0.0 0.23 11.8 0.0 2.9 2 1 1 3 3 3 1 Pirin C-terminal cupin domain Tubulin PF00091.25 PSC75915.1 - 8.1e-68 228.5 0.0 1.1e-67 228.0 0.0 1.2 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 PSC75915.1 - 3.2e-51 172.8 0.1 5e-51 172.1 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 PSC75915.1 - 0.0062 16.2 0.0 0.021 14.5 0.0 1.9 2 0 0 2 2 2 1 Tubulin domain Cytochrom_B561 PF03188.16 PSC75916.1 - 0.0023 18.1 3.7 0.0052 16.9 3.7 1.6 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 EptA_B_N PF08019.12 PSC75916.1 - 0.32 10.8 1.8 0.88 9.4 1.8 1.7 1 0 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB Pex14_N PF04695.13 PSC75917.1 - 1.6 9.4 16.0 2.3 8.9 16.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Suf PF05843.14 PSC75917.1 - 4 7.3 11.0 4.9 7.1 11.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Presenilin PF01080.17 PSC75917.1 - 5.3 5.7 6.1 5.5 5.7 6.1 1.1 1 0 0 1 1 1 0 Presenilin PA PF02225.22 PSC75918.1 - 9.1e-13 48.1 0.0 2.3e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 PA domain cEGF PF12662.7 PSC75918.1 - 0.00031 20.6 1.8 0.00031 20.6 1.8 3.9 4 0 0 4 4 4 1 Complement Clr-like EGF-like DUF3496 PF12001.8 PSC75920.1 - 3.7 8.0 12.0 0.54 10.7 2.7 4.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3496) FAM199X PF15814.5 PSC75921.1 - 1.3 8.0 3.7 3 6.8 3.7 1.6 1 0 0 1 1 1 0 Protein family FAM199X FAM199X PF15814.5 PSC75922.1 - 1.3 8.0 3.7 3 6.8 3.7 1.6 1 0 0 1 1 1 0 Protein family FAM199X Nucleotid_trans PF03407.16 PSC75923.1 - 4.3e-07 30.1 0.0 1.1e-06 28.8 0.0 1.6 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF1180 PF06679.12 PSC75923.1 - 0.11 12.9 0.1 0.15 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) CytB6-F_Fe-S PF08802.10 PSC75923.1 - 1.4 9.0 7.8 13 5.9 4.3 3.1 2 1 1 3 3 3 0 Cytochrome B6-F complex Fe-S subunit Trypsin PF00089.26 PSC75924.1 - 4.9e-17 62.5 0.0 1.1e-16 61.3 0.0 1.6 1 1 0 1 1 1 1 Trypsin SET PF00856.28 PSC75925.1 - 6.7e-05 23.3 0.9 0.31 11.4 0.0 3.0 3 0 0 3 3 3 2 SET domain SAF PF08666.12 PSC75925.1 - 0.016 15.8 0.0 9.7 6.9 0.0 2.8 2 0 0 2 2 2 0 SAF domain Fusion_gly PF00523.18 PSC75925.1 - 7.2 4.7 8.6 9.9 4.3 8.6 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 SET PF00856.28 PSC75926.1 - 0.00011 22.7 0.0 0.18 12.1 0.0 2.2 1 1 0 2 2 2 2 SET domain SAF PF08666.12 PSC75926.1 - 0.0083 16.7 0.0 7.7 7.2 0.0 2.7 2 0 0 2 2 2 2 SAF domain DUF1761 PF08570.10 PSC75928.1 - 3.6e-13 49.8 0.4 4.3e-13 49.6 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1761) CCDC53 PF10152.9 PSC75929.1 - 0.089 13.2 0.6 0.1 13.0 0.6 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Cnn_1N PF07989.11 PSC75930.1 - 0.14 12.3 0.1 1.5 9.0 0.0 2.6 2 1 1 3 3 3 0 Centrosomin N-terminal motif 1 PepSY_TM_like_2 PF16357.5 PSC75930.1 - 3.5 7.6 9.2 0.8 9.6 0.1 2.8 2 1 1 3 3 3 0 Putative PepSY_TM-like Trypsin_2 PF13365.6 PSC75931.1 - 8.9e-15 55.9 3.1 8.9e-15 55.9 3.1 1.5 2 0 0 2 2 2 1 Trypsin-like peptidase domain Vps26 PF03643.15 PSC75932.1 - 1.3e-93 313.0 0.0 1.6e-93 312.7 0.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 PSC75932.1 - 0.00032 20.8 0.0 4.8 7.2 0.0 3.5 4 0 0 4 4 4 3 Arrestin (or S-antigen), N-terminal domain DUF4719 PF15843.5 PSC75932.1 - 1.2 9.3 3.7 4.9 7.2 3.7 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4719) Histone PF00125.24 PSC75933.1 - 3.3e-16 59.8 0.3 4.4e-16 59.4 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 RP-C PF03428.13 PSC75933.1 - 0.017 14.8 0.7 1.3 8.7 0.0 2.1 1 1 1 2 2 2 0 Replication protein C N-terminal domain DnaJ PF00226.31 PSC75933.1 - 0.017 15.2 0.0 0.044 13.9 0.0 1.7 1 0 0 1 1 1 0 DnaJ domain CBFD_NFYB_HMF PF00808.23 PSC75933.1 - 0.023 14.9 0.1 0.023 14.9 0.1 1.7 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Ribosomal_L27 PF01016.19 PSC75934.1 - 6.3e-34 115.8 3.8 8.6e-34 115.4 2.5 1.8 2 0 0 2 2 2 1 Ribosomal L27 protein Phage_1_1 PF08200.11 PSC75934.1 - 0.29 11.6 1.7 13 6.3 0.0 2.7 2 1 0 2 2 2 0 Bacteriophage 1.1 Protein LRR_8 PF13855.6 PSC75935.1 - 4.1e-07 29.7 4.2 5.9e-07 29.1 1.4 2.3 2 0 0 2 2 2 1 Leucine rich repeat LRR_4 PF12799.7 PSC75935.1 - 2e-06 28.0 1.1 0.12 12.9 0.1 3.2 3 0 0 3 3 3 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 PSC75935.1 - 0.029 14.3 0.7 0.029 14.3 0.7 2.4 2 1 0 2 2 2 0 F-box-like Zip PF02535.22 PSC75936.1 - 1.9e-19 70.1 10.9 2.2e-19 69.8 10.9 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Atrophin-1 PF03154.15 PSC75936.1 - 0.82 7.9 5.0 1.2 7.4 5.0 1.1 1 0 0 1 1 1 0 Atrophin-1 family Zip PF02535.22 PSC75937.1 - 1.6e-19 70.3 10.2 2e-19 70.0 10.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter AMP-binding PF00501.28 PSC75938.1 - 1.6e-100 336.7 0.0 2.2e-100 336.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme rve PF00665.26 PSC75938.1 - 1.6e-18 67.0 0.0 3.6e-18 65.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain AMP-binding_C PF13193.6 PSC75938.1 - 0.00034 21.5 0.1 0.00099 20.0 0.1 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain rve_3 PF13683.6 PSC75938.1 - 0.033 13.9 0.0 0.033 13.9 0.0 1.9 2 0 0 2 2 2 0 Integrase core domain Patatin PF01734.22 PSC75940.1 - 8.2e-26 91.5 0.4 5.3e-25 88.8 0.1 2.3 2 0 0 2 2 2 1 Patatin-like phospholipase DUF3336 PF11815.8 PSC75940.1 - 1.1e-25 90.0 0.0 2.1e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Annexin PF00191.20 PSC75940.1 - 0.043 13.9 0.1 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Annexin Patatin PF01734.22 PSC75941.1 - 9.5e-26 91.2 0.4 5.3e-25 88.8 0.1 2.2 2 0 0 2 2 2 1 Patatin-like phospholipase DUF3336 PF11815.8 PSC75941.1 - 1.1e-25 90.0 0.0 2.1e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Annexin PF00191.20 PSC75941.1 - 0.043 13.9 0.1 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Annexin Patatin PF01734.22 PSC75942.1 - 8.2e-26 91.5 0.4 5.3e-25 88.8 0.1 2.3 2 0 0 2 2 2 1 Patatin-like phospholipase DUF3336 PF11815.8 PSC75942.1 - 1.1e-25 90.0 0.0 2.1e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3336) Annexin PF00191.20 PSC75942.1 - 0.043 13.9 0.1 0.15 12.1 0.0 1.9 2 0 0 2 2 2 0 Annexin Pex2_Pex12 PF04757.14 PSC75943.1 - 4.2e-33 114.8 0.0 7.2e-33 114.1 0.0 1.3 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 PSC75943.1 - 1.3e-10 40.9 5.6 2.2e-10 40.2 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC75943.1 - 1.2e-09 38.3 11.5 2.1e-09 37.6 11.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PSC75943.1 - 8e-09 35.2 9.0 1.4e-08 34.4 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PSC75943.1 - 1.9e-08 34.0 11.0 3.3e-08 33.2 11.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC75943.1 - 7.3e-08 32.3 5.4 7.3e-08 32.3 5.4 2.3 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PSC75943.1 - 1.2e-07 31.4 7.3 2.2e-07 30.6 7.3 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PSC75943.1 - 2.2e-06 27.7 6.0 2.2e-06 27.7 6.0 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 PSC75943.1 - 2.6e-06 27.3 8.1 7.5e-06 25.8 8.2 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 PSC75943.1 - 0.00014 22.1 13.5 0.00061 20.0 13.5 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_10 PF16685.5 PSC75943.1 - 0.097 12.8 5.2 0.19 11.9 5.2 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 PSC75943.1 - 0.15 12.1 2.7 0.32 11.1 2.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rtf2 PF04641.12 PSC75943.1 - 0.49 9.7 2.8 0.3 10.4 0.2 1.7 2 0 0 2 2 2 0 Rtf2 RING-finger TerY_C PF15616.6 PSC75943.1 - 1.3 9.2 4.6 2.3 8.3 4.6 1.3 1 0 0 1 1 1 0 TerY-C metal binding domain PhnA_Zn_Ribbon PF08274.12 PSC75943.1 - 1.3 9.0 4.5 10 6.1 1.1 2.6 2 0 0 2 2 2 0 PhnA Zinc-Ribbon zf-RING_4 PF14570.6 PSC75943.1 - 2.1 8.2 10.2 6.9 6.5 10.1 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Flavokinase PF01687.17 PSC75944.1 - 1.2e-25 89.9 0.0 2e-25 89.3 0.0 1.3 1 0 0 1 1 1 1 Riboflavin kinase HAD_2 PF13419.6 PSC75944.1 - 1.8e-25 90.1 0.0 2.5e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PSC75944.1 - 1.2e-19 71.4 0.7 2.7e-18 67.0 0.7 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PSC75944.1 - 4e-07 30.0 0.0 1.4e-06 28.3 0.0 1.9 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 PSC75944.1 - 9e-07 29.5 0.8 1.9e-06 28.4 0.1 1.8 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 PSC75944.1 - 0.00031 20.8 0.0 0.39 10.9 0.0 2.6 2 1 0 2 2 2 2 Haloacid dehalogenase-like hydrolase DUF4167 PF13763.6 PSC75944.1 - 0.27 11.4 0.5 0.6 10.3 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4167) Methyltransf_24 PF13578.6 PSC75946.1 - 5.2e-07 30.7 0.0 0.00074 20.5 0.0 3.2 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_3 PF01596.17 PSC75946.1 - 0.44 9.7 7.9 3.3 6.8 1.5 3.4 2 2 0 2 2 2 0 O-methyltransferase Seryl_tRNA_N PF02403.22 PSC75946.1 - 1.3 9.3 5.5 1.4 9.2 3.4 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HalX PF08663.10 PSC75946.1 - 1.7 9.1 8.6 0.29 11.5 2.8 2.7 2 1 1 3 3 3 0 HalX domain Methyltransf_24 PF13578.6 PSC75947.1 - 4.5e-05 24.4 0.0 0.0007 20.6 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.17 PSC75947.1 - 0.031 13.5 3.1 3.2 6.9 1.5 2.9 2 1 0 2 2 2 0 O-methyltransferase Seryl_tRNA_N PF02403.22 PSC75947.1 - 1.2 9.4 5.5 1.3 9.2 3.4 2.2 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain HalX PF08663.10 PSC75947.1 - 1.6 9.1 8.6 0.29 11.5 2.9 2.7 2 1 1 3 3 3 0 HalX domain ATG16 PF08614.11 PSC75947.1 - 6.4 7.0 10.2 0.22 11.7 3.2 2.1 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Ank_4 PF13637.6 PSC75948.1 - 1.5e-16 60.6 2.5 1e-06 29.2 0.1 4.4 2 2 3 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC75948.1 - 1e-14 54.4 3.8 6.8e-10 39.0 0.1 3.2 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PSC75948.1 - 1.7e-11 44.6 3.3 1.1e-05 25.9 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PSC75948.1 - 4.4e-06 26.6 2.8 0.25 12.0 0.0 5.5 5 1 1 6 6 6 1 Ankyrin repeat Ank PF00023.30 PSC75948.1 - 5.7e-06 26.6 19.9 0.012 16.1 0.2 5.5 5 2 0 5 5 5 3 Ankyrin repeat DUF3726 PF12525.8 PSC75948.1 - 0.075 13.1 1.2 0.25 11.5 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3726) Nitro_FeMo-Co PF02579.17 PSC75948.1 - 0.21 12.0 1.0 34 4.8 0.0 2.9 1 1 2 3 3 3 0 Dinitrogenase iron-molybdenum cofactor DUF2802 PF10975.8 PSC75948.1 - 2.2 8.4 5.1 4.7 7.4 0.0 3.3 4 0 0 4 4 4 0 Protein of unknown function (DUF2802) Prenylcys_lyase PF07156.14 PSC75950.1 - 1.1e-40 139.9 0.0 1.5e-16 60.5 0.0 3.0 2 1 1 3 3 3 3 Prenylcysteine lyase Alg6_Alg8 PF03155.15 PSC75951.1 - 3.6e-158 527.5 4.1 4.7e-158 527.1 4.1 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family ADH_zinc_N_2 PF13602.6 PSC75951.1 - 7.1e-30 104.8 0.1 1.5e-29 103.7 0.1 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 PSC75951.1 - 2.3e-11 43.8 0.2 4.1e-11 43.0 0.2 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PSC75951.1 - 0.00095 19.0 0.0 0.0095 15.8 0.0 2.2 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain HSP90 PF00183.18 PSC75952.1 - 1.4e-234 779.8 22.9 2.2e-234 779.2 22.9 1.3 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 PSC75952.1 - 3.2e-15 56.6 0.1 6.4e-15 55.6 0.1 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 PSC75952.1 - 3.9e-10 39.7 0.1 9.7e-10 38.4 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cofac_haem_bdg PF04187.13 PSC75952.1 - 0.18 11.8 1.1 0.76 9.7 1.1 2.0 1 1 0 1 1 1 0 Haem-binding uptake, Tiki superfamily, ChaN SUIM_assoc PF16619.5 PSC75953.1 - 0.028 14.5 2.6 0.028 14.5 2.6 3.4 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 PSC75953.1 - 0.59 9.7 14.2 0.9 9.1 2.4 2.2 2 0 0 2 2 2 0 Spt20 family 2OG-FeII_Oxy_3 PF13640.6 PSC75954.1 - 1.2e-07 32.5 0.0 2.9e-07 31.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 PSC75954.1 - 0.0006 20.4 0.0 0.0014 19.2 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_5 PF13759.6 PSC75954.1 - 0.82 10.1 0.0 0.82 10.1 0.0 2.9 3 1 0 3 3 3 0 Putative 2OG-Fe(II) oxygenase TFIIA PF03153.13 PSC75954.1 - 1.6 8.6 34.6 0.15 12.0 16.5 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Coilin_N PF15862.5 PSC75954.1 - 3.3 7.5 0.0 3.3 7.5 0.0 3.0 2 1 0 2 2 2 0 Coilin N-terminus DDHD PF02862.17 PSC75955.1 - 0.078 13.1 0.1 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 DDHD domain TFIIA PF03153.13 PSC75955.1 - 0.12 12.3 18.6 0.16 11.9 18.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 PSC75955.1 - 0.41 9.4 3.8 0.58 8.9 3.8 1.1 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 PSC75955.1 - 0.93 9.1 25.6 1.4 8.5 25.6 1.2 1 0 0 1 1 1 0 Spt20 family Med15 PF09606.10 PSC75955.1 - 3.2 6.3 27.0 6.3 5.4 27.0 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal RrnaAD PF00398.20 PSC75956.1 - 8.1e-61 205.4 0.0 1e-60 205.1 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 PSC75956.1 - 3.7e-08 34.0 0.0 2e-07 31.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC75956.1 - 7.4e-06 26.5 0.0 4e-05 24.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 PSC75956.1 - 1.9e-05 25.3 0.0 0.00026 21.7 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.16 PSC75956.1 - 0.0012 18.7 0.0 0.002 18.0 0.0 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.6 PSC75956.1 - 0.0021 17.9 0.0 0.0032 17.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 PSC75956.1 - 0.0023 17.7 0.0 0.0042 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_4 PF02390.17 PSC75956.1 - 0.003 17.1 0.0 0.0059 16.1 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.6 PSC75956.1 - 0.0076 16.1 0.0 0.022 14.6 0.0 1.8 3 0 0 3 3 3 1 Methyltransferase domain Cons_hypoth95 PF03602.15 PSC75956.1 - 0.014 15.0 0.0 0.045 13.4 0.0 1.7 2 0 0 2 2 2 0 Conserved hypothetical protein 95 PPS_PS PF02006.16 PSC75956.1 - 0.022 14.3 0.0 0.04 13.5 0.0 1.3 1 0 0 1 1 1 0 Phosphopantothenate/pantothenate synthetase NodS PF05401.11 PSC75956.1 - 0.022 14.4 0.0 0.036 13.7 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein S (NodS) MTS PF05175.14 PSC75956.1 - 0.029 13.9 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Met_10 PF02475.16 PSC75956.1 - 0.038 13.7 0.0 0.056 13.2 0.0 1.2 1 0 0 1 1 1 0 Met-10+ like-protein Ubie_methyltran PF01209.18 PSC75956.1 - 0.052 12.9 0.0 0.088 12.1 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DREV PF05219.12 PSC75956.1 - 0.067 12.3 0.0 0.19 10.8 0.0 1.7 2 0 0 2 2 2 0 DREV methyltransferase CMAS PF02353.20 PSC75956.1 - 0.16 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase Nucleotid_trans PF03407.16 PSC75957.1 - 2.3e-26 93.1 0.0 3.9e-26 92.4 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF2722 PF10846.8 PSC75957.1 - 0.00034 19.7 0.1 0.00034 19.7 0.1 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2722) Pkinase PF00069.25 PSC75958.1 - 3.1e-83 279.2 0.0 4.7e-42 144.2 0.0 3.0 2 2 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC75958.1 - 4.5e-71 239.2 0.0 3.9e-36 124.7 0.0 3.4 2 2 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 PSC75958.1 - 1e-07 31.6 0.1 0.014 14.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 PSC75958.1 - 3.2e-07 29.9 0.1 0.024 14.0 0.0 2.4 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PSC75958.1 - 2.7e-06 26.4 0.0 0.035 12.9 0.0 2.1 2 0 0 2 2 2 2 Fungal protein kinase Complex1_49kDa PF00346.19 PSC75958.1 - 0.17 11.0 0.0 6.5 5.8 0.0 2.2 2 0 0 2 2 2 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit APH PF01636.23 PSC75958.1 - 0.19 11.6 4.8 8.2 6.3 0.0 4.0 4 2 1 5 5 5 0 Phosphotransferase enzyme family Spc7 PF08317.11 PSC75960.1 - 0.034 13.0 28.8 0.64 8.9 11.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF1640 PF07798.11 PSC75960.1 - 0.67 10.0 13.9 1.9 8.5 12.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) COG2 PF06148.11 PSC75960.1 - 1.8 8.6 16.2 1 9.4 0.4 3.2 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 Sds3 PF08598.11 PSC75960.1 - 2.1 8.3 11.6 3.4 7.6 11.3 1.4 1 1 0 1 1 1 0 Sds3-like CorA PF01544.18 PSC75960.1 - 4.9 6.4 16.0 7.5 5.8 1.8 2.7 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein IBR PF01485.21 PSC75961.1 - 1.2e-23 83.1 21.1 6.1e-15 55.2 2.7 5.1 4 1 1 5 5 5 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 PSC75961.1 - 0.00013 21.7 3.7 0.00013 21.7 3.7 4.8 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC75961.1 - 0.00061 19.6 4.9 0.00061 19.6 4.9 4.7 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC75961.1 - 0.0052 17.1 5.2 0.0052 17.1 5.2 4.3 4 1 0 4 4 4 2 Ring finger domain zf-RING_UBOX PF13445.6 PSC75961.1 - 0.02 14.9 4.4 0.02 14.9 4.4 3.7 3 1 0 3 3 3 0 RING-type zinc-finger C2 PF00168.30 PSC75962.1 - 7e-16 58.4 0.0 3e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 C2 domain C2 PF00168.30 PSC75963.1 - 7e-16 58.4 0.0 3e-07 30.6 0.0 2.3 2 0 0 2 2 2 2 C2 domain Surp PF01805.20 PSC75964.1 - 2.2e-22 78.8 1.1 7.2e-10 38.7 0.2 2.4 2 0 0 2 2 2 2 Surp module DRY_EERY PF09750.9 PSC75964.1 - 1.7e-19 70.4 0.0 1.7e-19 70.4 0.0 5.4 6 0 0 6 6 6 1 Alternative splicing regulator Surp PF01805.20 PSC75965.1 - 2.1e-24 85.3 0.9 7.5e-12 45.1 0.2 2.4 2 0 0 2 2 2 2 Surp module DRY_EERY PF09750.9 PSC75965.1 - 1.7e-19 70.5 0.0 1.7e-19 70.5 0.0 5.4 6 0 0 6 6 6 1 Alternative splicing regulator PAN_4 PF14295.6 PSC75966.1 - 2.1e-09 37.2 7.1 3.1e-09 36.6 7.1 1.3 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 PSC75966.1 - 0.01 15.8 1.8 0.015 15.3 1.8 1.2 1 0 0 1 1 1 0 PAN domain Peptidase_M24 PF00557.24 PSC75967.1 - 2.1e-55 187.7 0.2 2.6e-55 187.4 0.2 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 E3_UFM1_ligase PF09743.9 PSC75968.1 - 4.4e-62 210.2 0.0 5.5e-62 209.9 0.0 1.1 1 0 0 1 1 1 1 E3 UFM1-protein ligase 1 FeoC PF09012.10 PSC75968.1 - 0.032 14.3 0.0 0.14 12.2 0.0 2.0 2 0 0 2 2 2 0 FeoC like transcriptional regulator DUF4485 PF14846.6 PSC75969.1 - 1.6e-18 66.5 0.0 3.2e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4485) EF-hand_1 PF00036.32 PSC75969.1 - 8.5e-07 28.1 0.2 2.2e-06 26.8 0.2 1.7 1 0 0 1 1 1 1 EF hand EF-hand_5 PF13202.6 PSC75969.1 - 1.6e-05 24.2 0.0 3.6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 PSC75969.1 - 4.3e-05 23.9 0.1 0.00012 22.4 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 PSC75969.1 - 0.0022 17.8 0.3 0.0057 16.5 0.4 1.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 PSC75969.1 - 0.0035 17.2 0.1 0.015 15.2 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain PMBR PF09373.10 PSC75969.1 - 0.19 11.9 0.0 0.5 10.6 0.0 1.7 1 0 0 1 1 1 0 Pseudomurein-binding repeat PITH PF06201.13 PSC75971.1 - 7.4e-40 136.6 0.0 8.4e-40 136.5 0.0 1.0 1 0 0 1 1 1 1 PITH domain Hus1 PF04005.12 PSC75971.1 - 0.098 11.8 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Hus1-like protein Homoserine_dh PF00742.19 PSC75972.1 - 7.9e-51 172.4 0.3 3.6e-50 170.2 0.0 2.3 3 0 0 3 3 3 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 PSC75972.1 - 2.6e-12 47.4 0.0 1.3e-11 45.2 0.0 2.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Herpes_UL3 PF03369.13 PSC75972.1 - 0.00052 20.6 2.8 0.88 10.1 0.2 2.6 2 0 0 2 2 2 2 Herpesvirus UL3 protein CorA PF01544.18 PSC75972.1 - 0.16 11.2 0.3 4 6.7 0.0 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein CCT PF06203.14 PSC75972.1 - 0.34 11.0 4.1 14 5.8 0.3 2.7 2 0 0 2 2 2 0 CCT motif Homoserine_dh PF00742.19 PSC75973.1 - 7.9e-51 172.4 0.3 3.6e-50 170.2 0.0 2.3 3 0 0 3 3 3 1 Homoserine dehydrogenase NAD_binding_3 PF03447.16 PSC75973.1 - 2.6e-12 47.4 0.0 1.3e-11 45.2 0.0 2.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain Herpes_UL3 PF03369.13 PSC75973.1 - 0.00052 20.6 2.8 0.88 10.1 0.2 2.6 2 0 0 2 2 2 2 Herpesvirus UL3 protein CorA PF01544.18 PSC75973.1 - 0.16 11.2 0.3 4 6.7 0.0 2.3 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein CCT PF06203.14 PSC75973.1 - 0.34 11.0 4.1 14 5.8 0.3 2.7 2 0 0 2 2 2 0 CCT motif Tim44 PF04280.15 PSC75974.1 - 1.3e-23 83.8 0.0 1.3e-23 83.8 0.0 1.7 2 0 0 2 2 2 1 Tim44-like domain TFIIA PF03153.13 PSC75974.1 - 0.074 13.0 10.0 0.083 12.9 10.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUIM_assoc PF16619.5 PSC75974.1 - 1.9 8.6 16.5 0.59 10.3 6.8 2.8 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Spt20 PF12090.8 PSC75974.1 - 2.9 7.4 17.6 4.4 6.8 17.6 1.2 1 0 0 1 1 1 0 Spt20 family API5 PF05918.11 PSC75974.1 - 4.2 6.1 8.6 5.7 5.6 8.6 1.2 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) SAP PF02037.27 PSC75975.1 - 1.9e-21 75.3 6.1 3.2e-12 45.9 0.2 4.2 4 0 0 4 4 4 2 SAP domain 4F5 PF04419.14 PSC75976.1 - 1.2e-09 38.8 20.7 7.5e-09 36.3 8.5 2.5 2 1 0 2 2 2 2 4F5 protein family DUF2570 PF10828.8 PSC75976.1 - 0.06 13.2 4.7 0.069 13.0 4.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) Rpp20 PF12328.8 PSC75976.1 - 0.29 11.1 5.3 0.32 11.0 5.3 1.0 1 0 0 1 1 1 0 Rpp20 subunit of nuclear RNase MRP and P Glyco_hydro_3_C PF01915.22 PSC75977.1 - 1.4e-41 142.7 0.0 2.6e-41 141.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Glyco_hydro_3 PF00933.21 PSC75977.1 - 3.2e-37 128.6 0.0 5e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain OTU PF02338.19 PSC75977.1 - 1e-15 58.4 0.0 2.5e-15 57.1 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 PSC75977.1 - 0.00072 19.1 0.2 0.77 9.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase C65 Otubain EMP70 PF02990.16 PSC75978.1 - 1.2e-162 542.3 18.0 7.9e-136 453.8 16.2 2.2 2 0 0 2 2 2 2 Endomembrane protein 70 PVL_ORF50 PF07768.11 PSC75978.1 - 0.067 13.5 0.5 0.13 12.6 0.5 1.4 1 0 0 1 1 1 0 PVL ORF-50-like family 2OG-FeII_Oxy_2 PF13532.6 PSC75979.1 - 1.4e-35 123.3 0.0 2.2e-35 122.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 PSC75979.1 - 0.07 13.6 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Put_Phosphatase PF06888.12 PSC75980.1 - 2.5e-47 161.2 0.0 9.9e-47 159.3 0.0 1.8 1 1 0 1 1 1 1 Putative Phosphatase HAD PF12710.7 PSC75980.1 - 0.005 17.2 0.7 0.005 17.2 0.7 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Lipase_GDSL_2 PF13472.6 PSC75981.1 - 6.3e-29 101.6 0.2 8.9e-29 101.1 0.2 1.2 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 PSC75981.1 - 2.2e-22 80.0 0.0 2.8e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase RRM_1 PF00076.22 PSC75982.1 - 2e-17 62.8 0.0 7.7e-08 32.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ceramidase PF05875.12 PSC75982.1 - 0.0086 15.5 0.7 0.3 10.5 0.0 2.1 2 0 0 2 2 2 1 Ceramidase RRM_occluded PF16842.5 PSC75982.1 - 0.035 14.0 0.0 4.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF4523 PF15023.6 PSC75982.1 - 0.059 13.2 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) Mito_fiss_reg PF05308.11 PSC75982.1 - 4.5 7.3 5.3 1.2 9.1 1.5 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator RRM_1 PF00076.22 PSC75983.1 - 2e-17 62.8 0.0 7.7e-08 32.0 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ceramidase PF05875.12 PSC75983.1 - 0.0086 15.5 0.7 0.3 10.5 0.0 2.1 2 0 0 2 2 2 1 Ceramidase RRM_occluded PF16842.5 PSC75983.1 - 0.035 14.0 0.0 4.4 7.3 0.0 2.5 2 0 0 2 2 2 0 Occluded RNA-recognition motif DUF4523 PF15023.6 PSC75983.1 - 0.059 13.2 0.0 0.21 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) Mito_fiss_reg PF05308.11 PSC75983.1 - 4.5 7.3 5.3 1.2 9.1 1.5 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator MIF4G_like_2 PF09090.11 PSC75984.1 - 1.5e-27 96.7 0.0 2.5e-27 96.0 0.0 1.3 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 PSC75984.1 - 1.7e-23 83.4 0.5 5.6e-23 81.7 0.5 1.7 1 1 1 2 2 2 1 MIF4G like MIF4G PF02854.19 PSC75984.1 - 0.023 14.3 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 MIF4G domain DUF2267 PF10025.9 PSC75984.1 - 0.13 12.5 3.7 6.4 7.1 0.0 3.6 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2267) BAR_3 PF16746.5 PSC75984.1 - 0.15 11.8 0.0 0.23 11.1 0.0 1.2 1 0 0 1 1 1 0 BAR domain of APPL family bZIP_2 PF07716.15 PSC75985.1 - 0.00038 20.5 3.0 0.00038 20.5 3.0 2.4 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 PSC75985.1 - 0.0024 17.9 1.1 0.0024 17.9 1.1 2.3 2 1 1 3 3 3 1 bZIP transcription factor KASH_CCD PF14662.6 PSC75985.1 - 0.0027 17.6 1.9 0.0042 16.9 1.9 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH TSC22 PF01166.18 PSC75985.1 - 0.0042 17.4 1.5 0.0065 16.8 1.5 1.4 1 0 0 1 1 1 1 TSC-22/dip/bun family YabA PF06156.13 PSC75985.1 - 0.0063 17.1 1.3 0.015 15.9 0.9 1.7 2 0 0 2 2 2 1 Initiation control protein YabA ABC_tran_CTD PF16326.5 PSC75985.1 - 0.0066 16.7 8.2 0.48 10.7 0.4 2.4 1 1 1 2 2 2 2 ABC transporter C-terminal domain Spc7 PF08317.11 PSC75985.1 - 0.019 13.9 4.7 0.021 13.7 4.7 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein Herpes_BLRF2 PF05812.12 PSC75985.1 - 0.02 15.0 1.2 0.036 14.2 1.2 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein DUF4055 PF13264.6 PSC75985.1 - 0.067 13.3 3.5 0.13 12.4 3.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4055) Tropomyosin PF00261.20 PSC75985.1 - 0.076 12.4 9.1 6.2 6.1 9.1 2.1 1 1 0 1 1 1 0 Tropomyosin Atg14 PF10186.9 PSC75985.1 - 0.084 11.9 1.4 0.092 11.8 1.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Sugarporin_N PF11471.8 PSC75985.1 - 0.087 12.8 14.5 3.4 7.7 0.8 3.1 2 1 0 2 2 2 0 Maltoporin periplasmic N-terminal extension Gal-3-0_sulfotr PF06990.11 PSC75985.1 - 0.11 11.4 0.7 0.12 11.2 0.7 1.0 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase Cortex-I_coil PF09304.10 PSC75985.1 - 0.12 12.6 4.7 2.9 8.1 4.7 2.1 1 1 0 1 1 1 0 Cortexillin I, coiled coil Prefoldin_2 PF01920.20 PSC75985.1 - 0.12 12.3 4.3 0.92 9.5 2.8 2.2 2 0 0 2 2 2 0 Prefoldin subunit DUF1664 PF07889.12 PSC75985.1 - 0.12 12.4 0.4 0.24 11.4 0.4 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) M PF02370.16 PSC75985.1 - 0.15 12.7 1.5 0.15 12.7 1.5 3.3 4 0 0 4 4 3 0 M protein repeat DUF724 PF05266.14 PSC75985.1 - 0.15 11.9 2.5 0.2 11.5 1.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) ZapB PF06005.12 PSC75985.1 - 0.2 12.1 6.9 0.77 10.2 4.8 2.3 2 1 0 2 2 2 0 Cell division protein ZapB CLZ PF16526.5 PSC75985.1 - 0.21 12.0 4.2 1.7 9.0 1.4 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels XhlA PF10779.9 PSC75985.1 - 0.26 11.5 1.2 2.8 8.2 0.5 2.3 2 1 1 3 3 3 0 Haemolysin XhlA SlyX PF04102.12 PSC75985.1 - 0.69 10.6 5.6 2.8 8.6 0.6 2.6 1 1 1 2 2 2 0 SlyX GIT_CC PF16559.5 PSC75985.1 - 2.2 8.2 5.2 4 7.4 0.2 2.8 3 1 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor BMFP PF04380.13 PSC75985.1 - 3 8.4 18.7 0.12 12.9 3.9 2.7 3 0 0 3 3 3 0 Membrane fusogenic activity APG6_N PF17675.1 PSC75985.1 - 3 8.4 12.0 22 5.6 12.0 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region TPR_MLP1_2 PF07926.12 PSC75985.1 - 3.8 7.6 12.7 6.7 6.8 4.8 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein DivIC PF04977.15 PSC75985.1 - 5.6 6.8 8.9 0.52 10.1 2.2 2.4 2 1 1 3 3 3 0 Septum formation initiator bZIP_2 PF07716.15 PSC75986.1 - 0.00025 21.1 7.0 0.00036 20.5 3.0 2.4 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_1 PF00170.21 PSC75986.1 - 0.0023 18.0 1.1 0.0023 18.0 1.1 2.3 2 1 1 3 3 3 1 bZIP transcription factor KASH_CCD PF14662.6 PSC75986.1 - 0.0025 17.7 1.9 0.004 17.0 1.9 1.4 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH TSC22 PF01166.18 PSC75986.1 - 0.004 17.4 1.5 0.0062 16.8 1.5 1.5 1 0 0 1 1 1 1 TSC-22/dip/bun family ABC_tran_CTD PF16326.5 PSC75986.1 - 0.0051 17.0 8.6 0.6 10.4 2.4 2.4 1 1 1 2 2 2 2 ABC transporter C-terminal domain YabA PF06156.13 PSC75986.1 - 0.007 17.0 1.7 0.014 16.0 0.9 1.8 2 0 0 2 2 2 1 Initiation control protein YabA Herpes_BLRF2 PF05812.12 PSC75986.1 - 0.018 15.1 1.2 0.034 14.3 1.2 1.5 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Sugarporin_N PF11471.8 PSC75986.1 - 0.026 14.5 14.2 1.2 9.2 7.0 3.1 1 1 1 2 2 2 0 Maltoporin periplasmic N-terminal extension Tropomyosin PF00261.20 PSC75986.1 - 0.036 13.4 8.9 0.41 10.0 6.1 2.0 1 1 1 2 2 2 0 Tropomyosin DUF4055 PF13264.6 PSC75986.1 - 0.051 13.7 3.4 0.07 13.3 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4055) KLRAQ PF10205.9 PSC75986.1 - 0.067 13.4 2.3 0.098 12.9 0.4 2.1 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Spc7 PF08317.11 PSC75986.1 - 0.087 11.7 5.5 0.1 11.5 5.5 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein Atg14 PF10186.9 PSC75986.1 - 0.092 11.8 2.1 0.1 11.7 2.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 GAS PF13851.6 PSC75986.1 - 0.1 11.9 5.3 0.29 10.4 3.0 1.7 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Cortex-I_coil PF09304.10 PSC75986.1 - 0.1 12.8 4.8 1.8 8.8 0.1 2.1 1 1 1 2 2 2 0 Cortexillin I, coiled coil DUF1664 PF07889.12 PSC75986.1 - 0.11 12.6 0.5 0.18 11.9 0.5 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Uso1_p115_C PF04871.13 PSC75986.1 - 0.12 12.7 6.6 0.24 11.8 6.6 1.6 1 1 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Prefoldin_2 PF01920.20 PSC75986.1 - 0.13 12.2 4.7 0.87 9.6 2.8 2.2 2 0 0 2 2 2 0 Prefoldin subunit M PF02370.16 PSC75986.1 - 0.14 12.8 1.5 0.14 12.8 1.5 3.3 4 0 0 4 4 3 0 M protein repeat Dynamitin PF04912.14 PSC75986.1 - 0.15 11.3 5.2 0.53 9.6 5.2 1.7 1 1 0 1 1 1 0 Dynamitin Gal-3-0_sulfotr PF06990.11 PSC75986.1 - 0.16 10.8 0.9 0.17 10.8 0.9 1.0 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase DHR10 PF18595.1 PSC75986.1 - 0.17 11.9 9.3 0.27 11.3 9.3 1.4 1 1 0 1 1 1 0 Designed helical repeat protein 10 domain DUF724 PF05266.14 PSC75986.1 - 0.18 11.6 3.1 0.2 11.5 1.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF724) ZapB PF06005.12 PSC75986.1 - 0.23 11.9 7.5 0.74 10.3 4.8 2.3 2 1 0 2 2 2 0 Cell division protein ZapB CLZ PF16526.5 PSC75986.1 - 0.24 11.8 4.7 1.6 9.1 1.5 2.3 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels PspB PF06667.12 PSC75986.1 - 0.25 11.4 1.6 2.2 8.4 0.1 2.2 2 0 0 2 2 2 0 Phage shock protein B XhlA PF10779.9 PSC75986.1 - 0.29 11.4 1.7 2.7 8.3 0.5 2.3 2 1 1 3 3 3 0 Haemolysin XhlA SlyX PF04102.12 PSC75986.1 - 0.84 10.3 6.2 2.7 8.6 0.6 2.6 1 1 1 2 2 2 0 SlyX Spc24 PF08286.11 PSC75986.1 - 0.93 9.8 3.7 1.4 9.2 1.2 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 GIT_CC PF16559.5 PSC75986.1 - 1 9.3 4.7 5.7 6.9 1.1 2.9 2 1 1 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor BMFP PF04380.13 PSC75986.1 - 1 9.9 17.5 0.12 12.9 3.9 2.7 3 0 0 3 3 3 0 Membrane fusogenic activity TPR_MLP1_2 PF07926.12 PSC75986.1 - 1.2 9.2 12.7 2.6 8.1 9.8 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein APG6_N PF17675.1 PSC75986.1 - 1.7 9.2 11.8 13 6.3 11.8 1.9 1 1 0 1 1 1 0 Apg6 coiled-coil region DivIC PF04977.15 PSC75986.1 - 2.9 7.7 8.6 0.36 10.6 1.8 2.5 1 1 2 3 3 3 0 Septum formation initiator VHL PF01847.16 PSC75987.1 - 1e-13 51.0 0.0 1.8e-13 50.2 0.0 1.4 1 0 0 1 1 1 1 VHL beta domain UbiA PF01040.18 PSC75988.1 - 2.3e-51 174.6 24.9 4e-51 173.7 24.9 1.4 1 0 0 1 1 1 1 UbiA prenyltransferase family SUIM_assoc PF16619.5 PSC75988.1 - 0.39 10.8 10.0 0.9 9.6 10.0 1.5 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Ribonuc_L-PSP PF01042.21 PSC75989.1 - 6.4e-40 135.9 0.0 8.6e-40 135.5 0.0 1.2 1 0 0 1 1 1 1 Endoribonuclease L-PSP Rab3-GTPase_cat PF13890.6 PSC75989.1 - 0.0082 15.8 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit E1_dh PF00676.20 PSC75990.1 - 1.2e-94 316.6 0.1 1.5e-94 316.3 0.1 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 PSC75990.1 - 2.9e-05 23.9 0.4 9.5e-05 22.2 0.4 1.9 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 PSC75990.1 - 0.0001 21.6 0.0 0.00017 20.9 0.0 1.2 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase adh_short_C2 PF13561.6 PSC75991.1 - 1.1e-53 182.3 0.0 1.4e-53 181.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 PSC75991.1 - 5.5e-44 150.0 0.1 6.7e-44 149.7 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 PSC75991.1 - 1.9e-09 37.7 0.0 2.8e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 KR domain PALP PF00291.25 PSC75991.1 - 0.0093 15.4 0.1 0.014 14.8 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Epimerase PF01370.21 PSC75991.1 - 0.017 14.6 0.1 0.057 12.9 0.1 1.6 1 1 1 2 2 2 0 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 PSC75991.1 - 0.11 11.8 0.2 0.17 11.2 0.2 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain PIG-U PF06728.13 PSC75992.1 - 2.9e-25 89.1 0.6 6.8e-25 87.9 0.0 1.9 2 0 0 2 2 2 1 GPI transamidase subunit PIG-U Lipoxygenase PF00305.19 PSC75994.1 - 1e-104 351.4 0.0 3.8e-56 190.9 0.0 2.3 1 1 1 2 2 2 2 Lipoxygenase Doppel PF11466.8 PSC75994.1 - 0.87 9.3 3.2 7.4 6.3 0.7 2.8 2 0 0 2 2 2 0 Prion-like protein Doppel Toxin_29 PF08116.11 PSC75994.1 - 1.2 9.2 20.6 0.68 10.0 5.8 2.8 2 0 0 2 2 2 0 PhTx neurotoxin family Cys_Knot_tox PF17486.2 PSC75994.1 - 1.4 9.2 17.4 4.5 7.6 4.6 2.6 2 0 0 2 2 2 0 Cystine knot toxins CEP44 PF15007.6 PSC75995.1 - 1.5e-32 112.5 0.0 2.4e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 Centrosomal spindle body, CEP44 5_nucleotid PF05761.14 PSC75996.1 - 1.4e-139 465.9 0.0 1.7e-139 465.7 0.0 1.0 1 0 0 1 1 1 1 5' nucleotidase family Hydrolase_like PF13242.6 PSC75996.1 - 0.15 12.2 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 HAD-hyrolase-like MULE PF10551.9 PSC75997.1 - 1.9e-05 25.0 0.0 3.7e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain DUF5616 PF18481.1 PSC75997.1 - 0.18 12.1 0.0 0.32 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5616) MULE PF10551.9 PSC75998.1 - 5.4e-10 39.6 0.0 9.5e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 MULE transposase domain DUF5616 PF18481.1 PSC75998.1 - 0.2 12.0 0.0 0.35 11.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5616) Hydrolase_4 PF12146.8 PSC75999.1 - 6.5e-13 48.5 0.1 7.3e-09 35.2 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PSC75999.1 - 1.5e-10 41.2 0.2 5.3e-08 32.8 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PSC75999.1 - 5.3e-08 33.7 10.1 5.3e-08 33.7 10.1 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 PSC75999.1 - 0.00015 21.4 0.0 0.00028 20.4 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF818 PF05677.12 PSC75999.1 - 0.0042 16.1 0.0 0.006 15.6 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) AXE1 PF05448.12 PSC75999.1 - 0.013 14.2 0.4 0.14 10.8 0.3 2.5 3 1 0 3 3 3 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 PSC75999.1 - 0.016 15.1 0.3 0.029 14.2 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 PSC75999.1 - 0.034 13.9 0.0 0.097 12.5 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 PSC75999.1 - 0.068 13.1 0.0 7.3 6.4 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.25 PSC75999.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 PSC75999.1 - 0.18 11.5 0.0 0.89 9.3 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family LIP PF03583.14 PSC75999.1 - 0.22 10.8 0.1 4.2 6.6 0.1 2.1 2 0 0 2 2 2 0 Secretory lipase Hydrolase_4 PF12146.8 PSC76000.1 - 6.5e-13 48.5 0.1 7.3e-09 35.2 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PSC76000.1 - 1.5e-10 41.2 0.2 5.3e-08 32.8 0.0 2.3 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PSC76000.1 - 5.3e-08 33.7 10.1 5.3e-08 33.7 10.1 2.1 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 PSC76000.1 - 0.00015 21.4 0.0 0.00028 20.4 0.0 1.4 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF818 PF05677.12 PSC76000.1 - 0.0042 16.1 0.0 0.006 15.6 0.0 1.1 1 0 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) AXE1 PF05448.12 PSC76000.1 - 0.013 14.2 0.4 0.14 10.8 0.3 2.5 3 1 0 3 3 3 0 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.13 PSC76000.1 - 0.016 15.1 0.3 0.029 14.2 0.0 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 PSC76000.1 - 0.034 13.9 0.0 0.097 12.5 0.0 1.6 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase BAAT_C PF08840.11 PSC76000.1 - 0.068 13.1 0.0 7.3 6.4 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Lipase_3 PF01764.25 PSC76000.1 - 0.16 11.9 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_5 PF12695.7 PSC76000.1 - 0.18 11.5 0.0 0.89 9.3 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family LIP PF03583.14 PSC76000.1 - 0.22 10.8 0.1 4.2 6.6 0.1 2.1 2 0 0 2 2 2 0 Secretory lipase SAYSvFN PF10260.9 PSC76001.1 - 3.6e-22 78.1 0.0 6.1e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) AP2 PF00847.20 PSC76001.1 - 4.8e-13 49.1 2.1 1.3e-07 31.7 0.0 2.9 2 0 0 2 2 2 2 AP2 domain W2 PF02020.18 PSC76002.1 - 2.9e-19 69.0 0.1 1.1e-18 67.1 0.1 2.0 1 0 0 1 1 1 1 eIF4-gamma/eIF5/eIF2-epsilon rve_2 PF13333.6 PSC76002.1 - 0.11 12.7 0.0 0.62 10.3 0.0 2.2 2 0 0 2 2 2 0 Integrase core domain Glyco_transf_92 PF01697.27 PSC76003.1 - 1.3e-05 25.0 0.0 2.4e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Glycosyltransferase family 92 Glyco_tranf_2_4 PF13704.6 PSC76003.1 - 0.008 16.7 0.0 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 AMP-binding PF00501.28 PSC76004.1 - 2.5e-78 263.6 0.0 3.7e-78 263.0 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme UbiA PF01040.18 PSC76004.1 - 2.4e-21 76.2 14.0 2.4e-21 76.2 14.0 4.8 4 1 0 4 4 4 1 UbiA prenyltransferase family PP-binding PF00550.25 PSC76004.1 - 4.5e-11 42.9 0.0 8.3e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site AMP-binding_C PF13193.6 PSC76004.1 - 3e-07 31.3 2.1 1.1e-06 29.6 0.5 2.7 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Hexapep PF00132.24 PSC76004.1 - 3.6e-07 29.7 17.2 0.28 11.0 0.2 7.4 5 2 2 7 7 7 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 PSC76004.1 - 5.3e-06 26.1 18.2 0.037 13.8 1.7 5.3 5 0 0 5 5 5 4 Hexapeptide repeat of succinyl-transferase Thioredoxin PF00085.20 PSC76005.1 - 2.8e-08 33.7 0.0 5.8e-08 32.7 0.0 1.5 2 0 0 2 2 2 1 Thioredoxin OST3_OST6 PF04756.13 PSC76005.1 - 0.029 13.7 0.0 0.034 13.5 0.0 1.2 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family HyaE PF07449.11 PSC76005.1 - 0.06 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE RRM_1 PF00076.22 PSC76006.1 - 2.1e-29 101.1 0.0 1.8e-15 56.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PSC76006.1 - 0.00021 21.2 0.0 0.59 10.2 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif Ribonuc_L-PSP PF01042.21 PSC76007.1 - 8.2e-20 71.0 0.0 1.3e-19 70.4 0.0 1.3 1 0 0 1 1 1 1 Endoribonuclease L-PSP Abhydrolase_3 PF07859.13 PSC76008.1 - 2.2e-10 40.7 7.5 3.6e-10 40.1 7.5 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 PSC76008.1 - 1.4e-06 27.4 0.2 0.00025 20.0 0.1 2.0 2 0 0 2 2 2 2 Carboxylesterase family Chlorophyllase2 PF12740.7 PSC76008.1 - 0.00058 18.8 0.2 0.00081 18.4 0.2 1.2 1 0 0 1 1 1 1 Chlorophyllase enzyme Thioesterase PF00975.20 PSC76008.1 - 0.036 14.2 0.5 0.07 13.2 0.5 1.4 1 0 0 1 1 1 0 Thioesterase domain DUF676 PF05057.14 PSC76008.1 - 0.092 12.2 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) CTP_transf_like PF01467.26 PSC76009.1 - 6.8e-09 36.0 0.0 1.4e-08 35.0 0.0 1.6 1 1 0 1 1 1 1 Cytidylyltransferase-like DUF1929 PF09118.11 PSC76010.1 - 6.1e-16 58.5 0.1 1.1e-15 57.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.11 PSC76010.1 - 2.1e-07 30.4 0.1 6.4e-06 25.5 0.0 3.0 3 1 0 3 3 3 1 Glyoxal oxidase N-terminus Kelch_6 PF13964.6 PSC76010.1 - 2.3e-06 27.7 0.1 0.029 14.7 0.0 4.5 4 0 0 4 4 4 2 Kelch motif SNF2_N PF00176.23 PSC76011.1 - 6.7e-51 173.1 0.0 1e-50 172.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC76011.1 - 1.4e-16 60.8 0.0 2.8e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 PSC76011.1 - 1.6e-10 40.7 9.8 1.6e-10 40.7 9.8 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC76011.1 - 6.7e-09 35.5 6.1 6.7e-09 35.5 6.1 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC76011.1 - 7.4e-09 35.3 8.8 7.4e-09 35.3 8.8 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC76011.1 - 1.6e-07 31.6 9.5 1.6e-07 31.6 9.5 2.5 2 0 0 2 2 1 1 Ring finger domain Prok-RING_4 PF14447.6 PSC76011.1 - 5.3e-07 29.4 7.1 1.2e-06 28.3 7.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PSC76011.1 - 4.2e-06 26.6 6.5 4.2e-06 26.6 6.5 2.0 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PSC76011.1 - 6.9e-06 26.0 6.1 1.6e-05 24.8 6.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PSC76011.1 - 1.2e-05 25.3 9.6 1.2e-05 25.3 9.6 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING YL1 PF05764.13 PSC76011.1 - 0.00058 20.1 22.3 0.12 12.5 18.1 3.8 2 1 0 2 2 2 2 YL1 nuclear protein zf-RING_10 PF16685.5 PSC76011.1 - 0.0014 18.7 3.5 0.0014 18.7 3.5 1.8 2 0 0 2 2 1 1 zinc RING finger of MSL2 ERCC3_RAD25_C PF16203.5 PSC76011.1 - 0.012 14.8 0.0 0.028 13.6 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-RING_4 PF14570.6 PSC76011.1 - 0.096 12.5 6.8 0.25 11.1 6.8 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 PSC76011.1 - 0.15 11.8 5.8 0.36 10.6 5.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger Suf PF05843.14 PSC76011.1 - 0.88 9.5 5.0 2.2 8.2 5.0 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-Nse PF11789.8 PSC76011.1 - 0.91 9.4 5.1 2 8.3 5.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.6 PSC76011.1 - 4.7 7.2 13.9 0.029 14.2 3.8 2.4 2 0 0 2 2 1 0 zf-RING of BARD1-type protein SNF2_N PF00176.23 PSC76012.1 - 7.1e-51 173.0 0.0 1.1e-50 172.4 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC76012.1 - 1.5e-16 60.7 0.0 2.9e-16 59.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_2 PF13923.6 PSC76012.1 - 1.6e-10 40.6 9.8 1.6e-10 40.6 9.8 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC76012.1 - 7e-09 35.4 6.1 7e-09 35.4 6.1 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC76012.1 - 7.7e-09 35.3 8.8 7.7e-09 35.3 8.8 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC76012.1 - 1.6e-07 31.5 9.5 1.6e-07 31.5 9.5 2.5 2 0 0 2 2 1 1 Ring finger domain Prok-RING_4 PF14447.6 PSC76012.1 - 5.6e-07 29.3 7.1 1.2e-06 28.2 7.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 PSC76012.1 - 4.3e-06 26.6 6.5 4.3e-06 26.6 6.5 2.0 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 PSC76012.1 - 7.3e-06 25.9 6.1 1.7e-05 24.8 6.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PSC76012.1 - 1.3e-05 25.2 9.6 1.3e-05 25.2 9.6 1.9 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING YL1 PF05764.13 PSC76012.1 - 0.00064 19.9 22.3 0.13 12.3 17.8 3.8 2 1 0 2 2 2 1 YL1 nuclear protein zf-RING_10 PF16685.5 PSC76012.1 - 0.0015 18.7 3.5 0.0015 18.7 3.5 1.8 2 0 0 2 2 1 1 zinc RING finger of MSL2 ERCC3_RAD25_C PF16203.5 PSC76012.1 - 0.013 14.7 0.0 0.03 13.6 0.0 1.5 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-RING_4 PF14570.6 PSC76012.1 - 0.1 12.4 6.8 0.26 11.1 6.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 PSC76012.1 - 0.16 11.8 5.8 0.37 10.6 5.8 1.7 1 0 0 1 1 1 0 RING-like zinc finger Suf PF05843.14 PSC76012.1 - 0.52 10.2 4.3 1.3 9.0 4.3 1.6 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) zf-Nse PF11789.8 PSC76012.1 - 0.92 9.4 5.1 2 8.3 5.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF2722 PF10846.8 PSC76012.1 - 1.6 7.6 10.8 3.2 6.6 10.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) zf-RING_6 PF14835.6 PSC76012.1 - 5.1 7.0 13.9 0.031 14.2 3.8 2.4 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Spt20 PF12090.8 PSC76012.1 - 7.9 6.0 16.5 16 5.1 16.5 1.4 1 0 0 1 1 1 0 Spt20 family rve PF00665.26 PSC76013.1 - 8.3e-19 67.9 0.0 1.8e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC76013.1 - 0.0066 16.2 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain AMP-binding PF00501.28 PSC76014.1 - 1e-82 278.0 0.1 1.2e-82 277.8 0.1 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PSC76014.1 - 7.5e-23 81.3 0.1 1.6e-22 80.3 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LAX PF15681.5 PSC76014.1 - 0.14 11.0 0.0 0.2 10.4 0.0 1.1 1 0 0 1 1 1 0 Lymphocyte activation family X Frataxin_Cyay PF01491.16 PSC76015.1 - 2e-10 40.7 0.0 2.3e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain Frataxin_Cyay PF01491.16 PSC76016.1 - 2e-10 40.7 0.0 2.3e-10 40.5 0.0 1.1 1 0 0 1 1 1 1 Frataxin-like domain PAP2 PF01569.21 PSC76017.1 - 2.2e-05 24.2 0.2 0.00019 21.2 0.0 2.1 2 0 0 2 2 2 1 PAP2 superfamily Prominin PF05478.11 PSC76018.1 - 0.0097 13.9 0.0 0.0097 13.9 0.0 2.1 2 0 0 2 2 2 1 Prominin kleA_kleC PF17383.2 PSC76018.1 - 0.046 14.1 0.2 18 5.8 0.0 3.4 3 0 0 3 3 3 0 Uncharacterized KorC regulated protein A Tweety PF04906.13 PSC76018.1 - 10 4.7 11.3 48 2.4 8.8 2.6 2 1 0 2 2 2 0 Tweety LysM PF01476.20 PSC76019.1 - 9.4e-33 112.0 1.7 1.4e-06 28.2 0.0 5.1 5 1 0 5 5 5 4 LysM domain Phage_tail_X PF05489.12 PSC76019.1 - 0.00023 20.7 1.6 0.016 14.9 0.1 3.4 3 1 0 3 3 3 2 Phage Tail Protein X 2OG-FeII_Oxy_3 PF13640.6 PSC76020.1 - 1.6e-11 44.9 0.0 3e-11 44.0 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Thioesterase PF00975.20 PSC76020.1 - 6.4e-11 42.8 0.0 1e-10 42.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF900 PF05990.12 PSC76020.1 - 0.046 13.2 0.0 0.11 11.9 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF900) TPM_phosphatase PF04536.14 PSC76021.1 - 5.5e-09 36.3 0.0 7.2e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 TPM domain Acyl-CoA_dh_1 PF00441.24 PSC76022.1 - 4.3e-12 46.5 0.1 8.1e-12 45.6 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 PSC76022.1 - 1.8e-11 44.1 0.0 4.7e-11 42.7 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.19 PSC76022.1 - 2.6e-08 33.7 0.0 4.5e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Toxin_5 PF05294.13 PSC76022.1 - 0.074 13.5 0.7 0.2 12.1 0.7 1.6 1 0 0 1 1 1 0 Scorpion short toxin DinB_2 PF12867.7 PSC76022.1 - 0.11 13.0 1.5 1.5 9.3 0.1 2.5 2 0 0 2 2 2 0 DinB superfamily Na_H_Exchanger PF00999.21 PSC76023.1 - 3.6e-47 161.0 40.3 5.7e-47 160.3 40.3 1.3 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family FA_desaturase PF00487.24 PSC76025.1 - 1.5e-17 64.3 24.6 1.5e-17 64.3 24.6 1.8 1 1 1 2 2 2 1 Fatty acid desaturase AAA_33 PF13671.6 PSC76026.1 - 7.4e-05 22.9 0.1 0.00016 21.8 0.1 1.6 1 0 0 1 1 1 1 AAA domain INTS5_N PF14837.6 PSC76026.1 - 0.23 11.0 0.0 0.36 10.4 0.0 1.3 1 0 0 1 1 1 0 Integrator complex subunit 5 N-terminus p450 PF00067.22 PSC76027.1 - 2e-43 148.8 0.0 2.6e-43 148.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pro_isomerase PF00160.21 PSC76028.1 - 3.7e-46 157.3 0.0 4.6e-46 157.0 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Voltage_CLC PF00654.20 PSC76029.1 - 4.6e-31 108.4 20.2 4.3e-20 72.3 6.5 3.5 5 0 0 5 5 5 2 Voltage gated chloride channel Voltage_CLC PF00654.20 PSC76030.1 - 5.2e-31 108.2 20.2 4.5e-20 72.2 6.5 3.4 5 0 0 5 5 5 2 Voltage gated chloride channel ANAPC4_WD40 PF12894.7 PSC76031.1 - 1.9e-11 44.1 0.2 0.026 14.8 0.0 5.9 4 1 2 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PSC76031.1 - 0.011 16.6 1.1 37 5.4 0.1 4.8 5 0 0 5 5 5 0 WD domain, G-beta repeat eIF2A PF08662.11 PSC76031.1 - 0.012 15.4 0.0 0.64 9.9 0.0 2.5 2 1 0 2 2 2 0 Eukaryotic translation initiation factor eIF2A DUF4157 PF13699.6 PSC76031.1 - 0.17 12.1 0.2 0.68 10.2 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4157) CLP_protease PF00574.23 PSC76032.1 - 3.3e-75 252.0 0.1 4.5e-75 251.5 0.1 1.2 1 0 0 1 1 1 1 Clp protease PPTA PF01239.22 PSC76033.1 - 2e-41 138.5 3.2 8.5e-09 34.9 0.3 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat SNO PF01174.19 PSC76034.1 - 9.6e-46 156.0 0.0 1.2e-45 155.7 0.0 1.1 1 0 0 1 1 1 1 SNO glutamine amidotransferase family GATase_3 PF07685.14 PSC76034.1 - 1.9e-08 34.2 0.0 2.9e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.28 PSC76034.1 - 0.0031 17.3 0.0 0.024 14.4 0.0 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_S51 PF03575.17 PSC76034.1 - 0.0087 15.7 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase family S51 DJ-1_PfpI PF01965.24 PSC76034.1 - 0.06 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 DJ-1/PfpI family TLD PF07534.16 PSC76035.1 - 2.6e-05 24.5 0.0 3.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 TLD SnoaL PF07366.12 PSC76036.1 - 2.7e-05 23.9 0.0 3.7e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 PSC76036.1 - 0.0014 19.2 0.0 0.0019 18.8 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain Kdo PF06293.14 PSC76037.1 - 1.8e-13 50.4 0.1 2.5e-13 49.9 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PSC76037.1 - 1.3e-11 44.9 1.8 2.5e-05 24.3 0.3 2.5 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 PSC76037.1 - 1e-10 41.5 0.0 1.2e-10 41.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 PSC76037.1 - 4e-09 36.4 0.0 6.2e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 PSC76037.1 - 5.4e-07 29.2 0.0 7.2e-07 28.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase EcKinase PF02958.20 PSC76037.1 - 0.0024 17.2 0.0 0.005 16.2 0.0 1.5 1 1 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 PSC76037.1 - 0.0054 16.3 0.0 0.0087 15.7 0.0 1.3 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kinase-like PF14531.6 PSC76037.1 - 0.015 14.7 0.0 0.021 14.1 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 PSC76037.1 - 0.049 12.4 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase Robl_LC7 PF03259.17 PSC76037.1 - 1.3 8.8 4.0 1.4 8.7 0.1 2.4 2 0 0 2 2 2 0 Roadblock/LC7 domain Kdo PF06293.14 PSC76038.1 - 7.4e-13 48.3 0.0 1.2e-12 47.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PSC76038.1 - 5.3e-11 42.9 0.8 7.9e-05 22.7 0.3 2.4 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase PF00069.25 PSC76038.1 - 3.3e-10 39.8 0.0 4.5e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.22 PSC76038.1 - 1.4e-08 34.6 0.0 2.2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 PSC76038.1 - 1.8e-06 27.4 0.0 2.7e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SnoaL PF07366.12 PSC76038.1 - 3.3e-05 23.7 0.0 7.3e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 PSC76038.1 - 6.4e-05 23.5 0.9 0.00025 21.6 0.0 2.2 2 0 0 2 2 2 1 SnoaL-like domain EcKinase PF02958.20 PSC76038.1 - 0.0071 15.7 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Ecdysteroid kinase Choline_kinase PF01633.20 PSC76038.1 - 0.013 15.1 0.0 0.021 14.4 0.0 1.3 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.6 PSC76038.1 - 0.034 13.4 0.0 0.051 12.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase_fungal PF17667.1 PSC76038.1 - 0.15 10.8 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase SnoaL PF07366.12 PSC76039.1 - 2.7e-05 23.9 0.0 3.7e-05 23.5 0.0 1.4 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase SnoaL_2 PF12680.7 PSC76039.1 - 0.0014 19.2 0.0 0.0019 18.8 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain GEMIN8 PF15348.6 PSC76040.1 - 0.13 12.6 1.2 0.23 11.8 1.2 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Myc_N PF01056.18 PSC76040.1 - 0.97 9.3 4.1 1.8 8.4 4.1 1.4 1 0 0 1 1 1 0 Myc amino-terminal region Nop14 PF04147.12 PSC76040.1 - 2.7 6.1 7.0 3.8 5.6 7.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF4746 PF15928.5 PSC76040.1 - 5.4 6.3 8.2 9.9 5.5 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Pox_Ag35 PF03286.14 PSC76040.1 - 5.8 6.7 6.3 9.8 5.9 6.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Pkinase PF00069.25 PSC76041.1 - 1.8e-68 230.7 0.0 2.4e-68 230.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC76041.1 - 1.5e-33 116.2 0.0 2.1e-33 115.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC76041.1 - 2e-08 33.9 0.0 3.2e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PSC76041.1 - 2.4e-05 23.8 0.6 4e-05 23.1 0.6 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family F-box-like PF12937.7 PSC76041.1 - 0.00036 20.4 0.9 0.00086 19.2 0.9 1.7 1 0 0 1 1 1 1 F-box-like Haspin_kinase PF12330.8 PSC76041.1 - 0.0004 19.4 0.1 0.00061 18.8 0.1 1.1 1 0 0 1 1 1 1 Haspin like kinase domain UBA PF00627.31 PSC76041.1 - 0.027 14.4 0.1 0.077 12.9 0.1 1.8 1 0 0 1 1 1 0 UBA/TS-N domain Seadorna_VP7 PF07387.11 PSC76041.1 - 0.11 11.5 0.0 0.17 10.9 0.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP7 Rhomboid PF01694.22 PSC76042.1 - 6.9e-12 45.6 2.3 1.1e-11 44.9 2.3 1.3 1 0 0 1 1 1 1 Rhomboid family RNA_POL_M_15KD PF02150.16 PSC76043.1 - 1.1e-10 41.2 0.9 1.1e-10 41.2 0.9 1.9 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 PSC76043.1 - 6.1e-10 38.8 2.6 6.1e-10 38.8 2.6 2.3 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Zn_Tnp_IS1595 PF12760.7 PSC76043.1 - 0.059 13.3 0.5 0.059 13.3 0.5 2.7 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF2197 PF09963.9 PSC76043.1 - 0.1 12.8 5.4 5.7 7.3 1.9 3.2 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2197) Elf1 PF05129.13 PSC76043.1 - 0.25 11.4 0.1 0.25 11.4 0.1 2.4 3 0 0 3 3 3 0 Transcription elongation factor Elf1 like zf-SNAP50_C PF12251.8 PSC76043.1 - 1.1 8.9 5.6 0.36 10.5 0.3 2.1 2 0 0 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal RPA_interact_C PF14768.6 PSC76043.1 - 1.4 9.5 6.4 27 5.4 1.5 3.4 3 1 0 3 3 3 0 Replication protein A interacting C-terminal Glyco_transf_90 PF05686.12 PSC76044.1 - 1.9e-20 73.1 0.2 2.2e-20 72.9 0.2 1.0 1 0 0 1 1 1 1 Glycosyl transferase family 90 Mito_carr PF00153.27 PSC76045.1 - 4.2e-60 199.7 1.1 5.9e-19 67.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Phage_tail_APC PF16778.5 PSC76046.1 - 0.062 13.2 0.0 17 5.4 0.0 2.5 2 0 0 2 2 2 0 Phage tail assembly chaperone protein Mt_ATP-synt_D PF05873.12 PSC76047.1 - 2.5e-11 43.7 1.4 3.1e-11 43.4 1.4 1.1 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) LigB PF02900.18 PSC76047.1 - 0.17 10.9 0.7 6.3 5.8 0.1 2.1 1 1 1 2 2 2 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase ABC_tran_CTD PF16326.5 PSC76047.1 - 1.7 9.0 15.0 3 8.2 3.7 3.3 2 1 1 3 3 3 0 ABC transporter C-terminal domain LRR_4 PF12799.7 PSC76048.1 - 2.6e-10 40.4 2.9 0.0023 18.3 0.3 4.7 5 0 0 5 5 5 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 PSC76048.1 - 1.9e-09 37.2 0.7 5e-09 35.9 0.7 1.7 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 PSC76048.1 - 9e-08 31.8 6.6 2.8e-05 23.8 1.1 3.6 2 1 1 3 3 3 2 Leucine rich repeat F-box PF00646.33 PSC76048.1 - 8.2e-05 22.4 0.1 0.00021 21.1 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box_5 PF18511.1 PSC76048.1 - 0.0056 16.2 0.1 0.011 15.3 0.1 1.4 1 0 0 1 1 1 1 F-box LRR_1 PF00560.33 PSC76048.1 - 0.025 15.1 1.3 1.3e+02 3.8 0.1 5.1 5 1 0 5 5 5 0 Leucine Rich Repeat Rotamase PF00639.21 PSC76051.1 - 3.9e-19 69.4 0.0 6.9e-19 68.6 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 PSC76051.1 - 3.4e-17 63.0 0.0 6.2e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_2 PF13145.6 PSC76051.1 - 0.00099 19.9 2.0 0.0022 18.8 0.0 2.2 2 0 0 2 2 2 1 PPIC-type PPIASE domain Haem_oxygenas_2 PF14518.6 PSC76051.1 - 5.6 6.7 7.5 0.18 11.6 1.1 1.8 2 0 0 2 2 2 0 Iron-containing redox enzyme 2_5_RNA_ligase2 PF13563.6 PSC76052.1 - 5.1e-36 123.9 0.5 7.8e-36 123.3 0.5 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily AIG2_2 PF13772.6 PSC76052.1 - 0.0098 16.3 0.0 0.017 15.5 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family Peptidase_M41 PF01434.18 PSC76053.1 - 2.5e-57 193.8 3.9 3.2e-57 193.5 1.5 2.3 2 0 0 2 2 2 1 Peptidase family M41 Ribonuclease_3 PF00636.26 PSC76053.1 - 7.8e-43 145.4 0.1 3e-20 72.8 0.1 2.8 2 0 0 2 2 2 2 Ribonuclease III domain AAA PF00004.29 PSC76053.1 - 4.2e-40 137.2 0.0 1.1e-39 135.8 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Ribonucleas_3_3 PF14622.6 PSC76053.1 - 5.5e-30 104.2 1.4 3.2e-12 46.7 1.1 3.5 3 0 0 3 3 3 3 Ribonuclease-III-like Carb_anhydrase PF00194.21 PSC76053.1 - 7.7e-27 94.4 0.0 1.6e-26 93.4 0.0 1.4 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase Dicer_dimer PF03368.14 PSC76053.1 - 4.8e-17 61.9 2.1 3.4e-16 59.2 0.1 3.1 2 0 0 2 2 2 1 Dicer dimerisation domain AAA_lid_3 PF17862.1 PSC76053.1 - 1.4e-12 47.2 0.1 5.3e-12 45.3 0.1 2.1 1 0 0 1 1 1 1 AAA+ lid domain Helicase_C PF00271.31 PSC76053.1 - 3.7e-07 30.5 0.0 8.2e-07 29.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain PAZ PF02170.22 PSC76053.1 - 7.5e-06 25.8 0.0 9.9e-05 22.2 0.0 2.1 2 0 0 2 2 2 1 PAZ domain AAA_5 PF07728.14 PSC76053.1 - 0.00014 21.9 0.1 0.00045 20.2 0.0 1.9 2 0 0 2 2 1 1 AAA domain (dynein-related subfamily) ResIII PF04851.15 PSC76053.1 - 0.00019 21.5 0.2 0.018 15.1 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit FAD_binding_1 PF00667.20 PSC76053.1 - 0.0025 17.4 0.1 0.32 10.5 0.1 2.4 2 0 0 2 2 2 1 FAD binding domain AAA_28 PF13521.6 PSC76053.1 - 0.013 15.8 0.1 0.075 13.3 0.1 2.4 1 0 0 1 1 1 0 AAA domain NAD_binding_1 PF00175.21 PSC76053.1 - 0.015 15.9 0.0 0.04 14.6 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain TIP49 PF06068.13 PSC76053.1 - 0.021 14.1 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain DEAD PF00270.29 PSC76053.1 - 0.025 14.3 0.0 0.15 11.9 0.0 2.2 3 0 0 3 3 3 0 DEAD/DEAH box helicase DUF4055 PF13264.6 PSC76053.1 - 0.026 14.7 0.6 0.53 10.4 0.4 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4055) AAA_22 PF13401.6 PSC76053.1 - 0.028 14.7 0.1 1.1 9.5 0.1 2.9 3 0 0 3 3 2 0 AAA domain RuvB_N PF05496.12 PSC76053.1 - 0.035 13.9 0.0 0.085 12.6 0.0 1.6 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PSC76053.1 - 0.036 14.5 0.2 0.036 14.5 0.2 4.7 5 1 0 6 6 3 0 AAA ATPase domain FAD_binding_6 PF00970.24 PSC76053.1 - 0.062 13.7 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Lipoxygenase PF00305.19 PSC76055.1 - 5.8e-13 48.2 0.0 2.9e-10 39.3 0.0 2.2 1 1 0 1 1 1 1 Lipoxygenase OTU PF02338.19 PSC76056.1 - 1.9e-06 28.4 0.0 2.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease ubiquitin PF00240.23 PSC76056.1 - 0.00013 21.7 0.0 0.0004 20.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin family UIM PF02809.20 PSC76056.1 - 0.00014 21.5 1.1 0.00014 21.5 1.1 2.2 2 0 0 2 2 2 1 Ubiquitin interaction motif UN_NPL4 PF11543.8 PSC76056.1 - 0.23 12.0 0.0 0.73 10.4 0.0 1.8 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 OTU PF02338.19 PSC76057.1 - 1.9e-06 28.4 0.0 2.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease ubiquitin PF00240.23 PSC76057.1 - 0.00013 21.7 0.0 0.0004 20.1 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin family UIM PF02809.20 PSC76057.1 - 0.00014 21.5 1.1 0.00014 21.5 1.1 2.2 2 0 0 2 2 2 1 Ubiquitin interaction motif UN_NPL4 PF11543.8 PSC76057.1 - 0.23 12.0 0.0 0.73 10.4 0.0 1.8 1 1 0 1 1 1 0 Nuclear pore localisation protein NPL4 Ras PF00071.22 PSC76058.1 - 4.5e-65 218.2 0.3 5.3e-65 218.0 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 PSC76058.1 - 3.4e-35 120.9 0.4 5.1e-35 120.3 0.4 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 PSC76058.1 - 1.3e-16 60.5 0.2 1.5e-16 60.3 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 PSC76058.1 - 4.1e-07 29.6 0.2 5.4e-07 29.2 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 PSC76058.1 - 8.9e-05 22.6 0.1 0.00014 22.0 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 PSC76058.1 - 0.00067 19.6 0.2 0.17 11.8 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 PSC76058.1 - 0.00084 18.9 0.2 0.0034 17.0 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 PSC76058.1 - 0.00087 18.8 0.0 0.0011 18.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_16 PF13191.6 PSC76058.1 - 0.0036 17.7 0.0 0.0093 16.4 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 PSC76058.1 - 0.0086 16.1 0.0 0.039 13.9 0.0 1.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) MCM PF00493.23 PSC76058.1 - 0.035 13.2 0.0 0.099 11.7 0.0 1.7 2 0 0 2 2 2 0 MCM P-loop domain AAA_29 PF13555.6 PSC76058.1 - 0.05 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 PSC76058.1 - 0.059 13.7 0.1 0.51 10.6 0.0 2.3 2 1 1 3 3 3 0 AAA domain SNF2_N PF00176.23 PSC76058.1 - 0.062 12.0 0.0 0.075 11.7 0.0 1.1 1 0 0 1 1 1 0 SNF2 family N-terminal domain PduV-EutP PF10662.9 PSC76058.1 - 0.099 12.4 0.2 1.2 8.8 0.2 2.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 PSC76058.1 - 0.11 12.0 0.0 0.23 10.8 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein NACHT PF05729.12 PSC76058.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain 6PGD PF00393.19 PSC76060.1 - 7.7e-119 396.4 0.0 1.2e-118 395.7 0.0 1.3 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain XRN_M PF17846.1 PSC76060.1 - 7.1e-101 338.3 0.0 1.2e-100 337.5 0.0 1.3 1 0 0 1 1 1 1 Xrn1 helical domain XRN_N PF03159.18 PSC76060.1 - 2.4e-78 262.9 0.0 3e-38 131.6 0.0 2.3 1 1 1 2 2 2 2 XRN 5'-3' exonuclease N-terminus NAD_binding_2 PF03446.15 PSC76060.1 - 7.2e-47 159.5 0.2 1.4e-46 158.5 0.2 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase XRN1_D1 PF18332.1 PSC76060.1 - 2.5e-40 138.3 0.0 4e-40 137.6 0.0 1.3 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D1 domain SH3_12 PF18129.1 PSC76060.1 - 4.5e-13 49.1 0.3 9.4e-13 48.1 0.3 1.6 1 0 0 1 1 1 1 Xrn1 SH3-like domain XRN1_D2_D3 PF18334.1 PSC76060.1 - 0.0005 20.2 0.0 0.057 13.6 0.0 3.1 2 1 0 2 2 2 1 Exoribonuclease Xrn1 D2/D3 domain 3HCDH_N PF02737.18 PSC76060.1 - 0.059 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Pox_VLTF3 PF04947.14 PSC76060.1 - 0.27 11.0 0.1 0.44 10.3 0.1 1.2 1 0 0 1 1 1 0 Poxvirus Late Transcription Factor VLTF3 like Ribosomal_L29 PF00831.23 PSC76061.1 - 1.7e-20 72.7 0.4 1.7e-20 72.7 0.4 1.7 2 0 0 2 2 2 1 Ribosomal L29 protein Amino_oxidase PF01593.24 PSC76062.1 - 1.5e-60 205.8 0.0 2e-60 205.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PSC76062.1 - 2.3e-15 56.5 0.0 6e-15 55.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain MCRA PF06100.11 PSC76062.1 - 7.3e-07 28.4 0.0 0.023 13.5 0.0 2.2 2 0 0 2 2 2 2 MCRA family DAO PF01266.24 PSC76062.1 - 9.2e-07 28.7 0.3 7.4e-05 22.5 0.1 2.6 2 1 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 PSC76062.1 - 7.7e-05 21.9 0.3 0.00049 19.3 0.2 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_2 PF07992.14 PSC76062.1 - 0.00056 19.2 0.0 0.0031 16.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 PSC76062.1 - 0.00077 18.9 0.1 0.0017 17.8 0.0 1.5 2 0 0 2 2 2 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 PSC76062.1 - 0.0016 17.8 0.0 0.003 16.9 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 PSC76062.1 - 0.0032 16.2 0.1 0.0059 15.4 0.1 1.4 1 0 0 1 1 1 1 HI0933-like protein AlaDh_PNT_C PF01262.21 PSC76062.1 - 0.0055 16.0 0.1 0.15 11.3 0.0 2.2 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain NAD_binding_9 PF13454.6 PSC76062.1 - 0.013 15.5 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox PF00070.27 PSC76062.1 - 0.042 14.4 0.1 0.15 12.7 0.1 1.9 2 0 0 2 2 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 PSC76062.1 - 0.14 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lactamase_B PF00753.27 PSC76063.1 - 4.4e-17 62.7 2.2 9.7e-17 61.6 2.2 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PSC76063.1 - 2.5e-09 37.0 1.0 5.7e-09 35.8 1.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Resolvase PF00239.21 PSC76063.1 - 4e-07 30.2 0.3 3.7e-06 27.1 0.0 2.7 3 0 0 3 3 3 1 Resolvase, N terminal domain DUF563 PF04577.14 PSC76063.1 - 4.2e-07 30.3 0.0 9e-07 29.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF563) HupF_HypC PF01455.18 PSC76063.1 - 0.022 14.9 0.2 0.71 10.1 0.0 3.0 3 0 0 3 3 3 0 HupF/HypC family Lactamase_B_6 PF16661.5 PSC76063.1 - 0.029 13.8 0.0 0.049 13.1 0.0 1.3 1 0 0 1 1 1 0 Metallo-beta-lactamase superfamily domain NUDIX PF00293.28 PSC76064.1 - 4.1e-23 81.8 0.2 4.7e-23 81.7 0.2 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 PSC76064.1 - 0.0011 18.9 0.0 0.0014 18.6 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain UbiA PF01040.18 PSC76066.1 - 8e-37 126.9 14.9 1.1e-36 126.4 14.9 1.3 1 0 0 1 1 1 1 UbiA prenyltransferase family Kunitz_BPTI PF00014.23 PSC76067.1 - 1.2e-52 175.9 33.9 3.1e-19 69.0 10.1 3.1 3 0 0 3 3 3 3 Kunitz/Bovine pancreatic trypsin inhibitor domain RRM_1 PF00076.22 PSC76068.1 - 2.3e-18 65.8 0.0 3.1e-18 65.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 PSC76068.1 - 0.015 15.0 0.0 0.067 12.9 0.0 2.2 1 0 0 1 1 1 0 Ribonuclease B OB domain Apt1 PF10351.9 PSC76068.1 - 1.2 7.9 11.1 1.4 7.7 11.1 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain RSRP PF17069.5 PSC76068.1 - 5.3 6.5 67.8 7.3 6.1 67.8 1.1 1 0 0 1 1 1 0 Arginine/Serine-Rich protein 1 NPR3 PF03666.13 PSC76068.1 - 9.2 4.9 6.9 9.9 4.8 6.9 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 rve PF00665.26 PSC76069.1 - 8.3e-19 67.9 0.0 1.8e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC76069.1 - 0.0066 16.2 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain ThylakoidFormat PF11264.8 PSC76070.1 - 3.6e-62 209.9 0.0 4.6e-62 209.5 0.0 1.1 1 0 0 1 1 1 1 Thylakoid formation protein DUF2826 PF11442.8 PSC76070.1 - 0.074 12.9 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2826) PPDK_N PF01326.19 PSC76071.1 - 9e-24 84.3 0.0 2.9e-17 63.0 0.0 4.1 1 1 1 2 2 2 2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain DUF2934 PF11154.8 PSC76071.1 - 0.0012 18.5 0.3 0.051 13.3 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2934) CCDC53 PF10152.9 PSC76071.1 - 0.59 10.5 9.0 3.1 8.2 4.8 2.3 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex RCR PF12273.8 PSC76071.1 - 3.4 8.4 12.9 8.3 7.1 12.9 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red TFIIA PF03153.13 PSC76071.1 - 8.1 6.3 13.1 15 5.4 13.1 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF155 PF02582.14 PSC76072.1 - 2.6e-45 154.7 0.0 3.6e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 PARP PF00644.20 PSC76073.1 - 4.1e-19 68.9 0.0 4.2e-17 62.4 0.0 3.0 2 1 1 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain UBA PF00627.31 PSC76073.1 - 9.1e-14 51.0 5.0 0.00022 21.1 0.0 3.8 3 0 0 3 3 3 3 UBA/TS-N domain UQ_con PF00179.26 PSC76073.1 - 3.5e-05 23.5 0.0 0.00013 21.6 0.0 1.9 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme UBA_4 PF14555.6 PSC76073.1 - 0.00096 18.9 1.8 0.15 11.9 0.3 3.3 3 0 0 3 3 3 1 UBA-like domain CUE PF02845.16 PSC76073.1 - 0.076 12.7 0.5 1.2 8.9 0.2 2.8 3 0 0 3 3 3 0 CUE domain Pex14_N PF04695.13 PSC76073.1 - 0.13 12.9 22.6 0.41 11.3 22.6 1.8 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DMA PF03474.14 PSC76073.1 - 0.15 11.6 0.7 1.2 8.8 0.3 2.4 2 0 0 2 2 2 0 DMRTA motif Ndc1_Nup PF09531.10 PSC76073.1 - 0.34 9.5 4.0 0.5 9.0 4.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 PSC76073.1 - 0.5 10.3 30.6 0.038 14.0 25.2 1.7 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit FHIPEP PF00771.20 PSC76073.1 - 0.82 8.1 3.8 1.3 7.4 3.8 1.2 1 0 0 1 1 1 0 FHIPEP family PAT1 PF09770.9 PSC76073.1 - 1.2 7.4 20.3 1.7 6.8 20.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.12 PSC76073.1 - 3.9 6.3 12.9 5.7 5.8 12.9 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Presenilin PF01080.17 PSC76073.1 - 5.9 5.5 9.4 9.5 4.9 9.4 1.2 1 0 0 1 1 1 0 Presenilin 4HBT PF03061.22 PSC76074.1 - 0.026 14.9 0.0 0.026 14.9 0.0 2.0 2 0 0 2 2 2 0 Thioesterase superfamily AAA PF00004.29 PSC76075.1 - 1.2e-36 126.0 0.0 3.3e-36 124.6 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) S4 PF01479.25 PSC76075.1 - 1.1e-13 50.6 0.8 3.5e-13 49.0 0.8 1.9 1 0 0 1 1 1 1 S4 domain AAA_lid_3 PF17862.1 PSC76075.1 - 3.3e-06 26.8 0.2 8.6e-06 25.5 0.2 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 PSC76075.1 - 1.5e-05 25.3 5.4 0.037 14.3 0.4 4.3 3 1 0 3 3 3 1 AAA domain RuvB_N PF05496.12 PSC76075.1 - 2.1e-05 24.3 0.0 4.5e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 PSC76075.1 - 0.00015 21.1 0.4 0.00063 19.1 0.1 1.8 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 PSC76075.1 - 0.00018 21.5 0.1 0.00058 19.9 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.10 PSC76075.1 - 0.0046 16.9 0.0 0.038 14.0 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain Mg_chelatase PF01078.21 PSC76075.1 - 0.01 15.2 0.1 0.021 14.2 0.1 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 PSC76075.1 - 0.016 15.6 3.6 0.2 12.0 0.1 3.3 2 1 1 3 3 3 0 AAA ATPase domain IstB_IS21 PF01695.17 PSC76075.1 - 0.021 14.6 0.0 0.041 13.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_18 PF13238.6 PSC76075.1 - 0.022 15.3 0.2 0.11 13.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 PSC76075.1 - 0.073 13.2 0.0 2.3 8.4 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 PSC76075.1 - 0.091 12.9 0.0 0.23 11.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) zf-TRAF_2 PF15965.5 PSC76075.1 - 0.19 12.2 0.0 1 9.9 0.0 1.9 2 0 0 2 2 2 0 TRAF-like zinc-finger RNA_helicase PF00910.22 PSC76075.1 - 0.22 11.9 0.0 0.43 11.0 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_24 PF13479.6 PSC76075.1 - 0.24 11.1 0.0 0.44 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain TPR_2 PF07719.17 PSC76076.1 - 1.8e-32 108.8 75.8 5.4e-06 26.1 0.7 19.4 19 0 0 19 19 19 10 Tetratricopeptide repeat TPR_1 PF00515.28 PSC76076.1 - 9.5e-32 107.5 38.3 3.2e-07 29.9 0.3 15.9 17 0 0 17 17 16 7 Tetratricopeptide repeat TPR_8 PF13181.6 PSC76076.1 - 1e-21 75.2 25.0 4.6e-05 23.3 0.1 15.7 19 0 0 19 19 19 3 Tetratricopeptide repeat TPR_14 PF13428.6 PSC76076.1 - 5.6e-21 73.5 164.7 0.0014 19.2 1.2 24.8 15 5 10 26 26 23 13 Tetratricopeptide repeat TPR_19 PF14559.6 PSC76076.1 - 3.9e-20 72.1 92.2 6.2e-05 23.4 2.2 16.5 12 4 5 17 17 16 8 Tetratricopeptide repeat TPR_11 PF13414.6 PSC76076.1 - 3.5e-19 68.2 39.7 0.042 13.5 0.1 15.0 14 3 2 16 16 16 6 TPR repeat TPR_17 PF13431.6 PSC76076.1 - 3.2e-11 42.8 22.3 2.3 8.8 0.0 13.2 14 0 0 14 14 13 3 Tetratricopeptide repeat TPR_7 PF13176.6 PSC76076.1 - 1.5e-09 37.2 50.4 0.0037 17.2 0.1 14.0 17 0 0 17 17 15 5 Tetratricopeptide repeat TPR_16 PF13432.6 PSC76076.1 - 5.9e-09 36.4 31.1 2.1e-07 31.4 5.5 21.2 14 5 7 21 21 18 9 Tetratricopeptide repeat TPR_12 PF13424.6 PSC76076.1 - 8.5e-08 32.4 116.6 0.00081 19.6 0.6 15.9 14 3 1 16 16 15 7 Tetratricopeptide repeat TPR_9 PF13371.6 PSC76076.1 - 1.9e-06 27.9 0.2 1.9e-06 27.9 0.2 12.6 10 2 1 12 12 12 4 Tetratricopeptide repeat ANAPC3 PF12895.7 PSC76076.1 - 0.00014 22.0 22.1 0.057 13.7 1.9 7.2 6 3 1 7 7 7 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 PSC76076.1 - 0.061 13.2 56.9 1 9.3 0.4 13.0 14 0 0 14 14 13 0 Tetratricopeptide repeat DUF3856 PF12968.7 PSC76076.1 - 0.19 11.8 17.5 0.51 10.4 0.5 5.9 5 1 1 6 6 6 0 Domain of Unknown Function (DUF3856) DUF4810 PF16068.5 PSC76076.1 - 0.77 10.3 4.8 4.6 7.8 0.0 4.5 5 0 0 5 5 4 0 Domain of unknown function (DUF4810) MIT PF04212.18 PSC76076.1 - 3.2 7.9 0.0 3.2 7.9 0.0 5.8 7 0 0 7 7 5 0 MIT (microtubule interacting and transport) domain PTCB-BRCT PF12738.7 PSC76077.1 - 4e-12 45.9 0.0 2.4e-07 30.6 0.0 3.3 3 0 0 3 3 3 2 twin BRCT domain BRCT PF00533.26 PSC76077.1 - 6.8e-12 45.6 0.0 1.4e-05 25.3 0.0 2.3 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 PSC76077.1 - 2.9e-08 34.0 0.0 0.0052 17.2 0.0 2.3 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain FA_desaturase PF00487.24 PSC76078.1 - 8.7e-27 94.6 17.6 8.7e-27 94.6 17.6 1.6 2 0 0 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.10 PSC76078.1 - 7e-10 38.2 0.3 1.4e-09 37.2 0.3 1.6 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) PAN_4 PF14295.6 PSC76078.1 - 0.0078 16.1 4.4 0.023 14.6 4.4 1.8 1 0 0 1 1 1 1 PAN domain PAN_1 PF00024.26 PSC76078.1 - 0.012 15.6 2.1 0.021 14.8 2.1 1.4 1 0 0 1 1 1 0 PAN domain UBA PF00627.31 PSC76079.1 - 3.2e-17 62.1 1.7 1.4e-08 34.5 0.0 3.3 3 0 0 3 3 3 2 UBA/TS-N domain BUD22 PF09073.10 PSC76079.1 - 4.7 6.5 32.2 0.3 10.4 13.7 2.1 2 0 0 2 2 2 0 BUD22 Bap31_Bap29_C PF18035.1 PSC76080.1 - 5.3e-10 39.2 5.1 3.5e-07 30.1 3.2 2.5 2 0 0 2 2 2 2 Bap31/Bap29 cytoplasmic coiled-coil domain KASH_CCD PF14662.6 PSC76080.1 - 9.1e-05 22.4 3.8 0.0002 21.3 3.8 1.5 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH GAS PF13851.6 PSC76080.1 - 0.0003 20.2 0.9 0.00058 19.3 0.9 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding APG6_N PF17675.1 PSC76080.1 - 0.00043 20.8 10.2 0.00097 19.7 10.2 1.6 1 1 0 1 1 1 1 Apg6 coiled-coil region Fez1 PF06818.15 PSC76080.1 - 0.0017 18.8 0.8 0.0034 17.9 0.8 1.5 1 0 0 1 1 1 1 Fez1 ADIP PF11559.8 PSC76080.1 - 0.0021 18.2 4.9 0.0038 17.3 4.9 1.3 1 0 0 1 1 1 1 Afadin- and alpha -actinin-Binding DUF3584 PF12128.8 PSC76080.1 - 0.0029 15.2 4.2 0.004 14.8 4.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Methyltransf_31 PF13847.6 PSC76080.1 - 0.0035 17.2 0.0 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain UPF0242 PF06785.11 PSC76080.1 - 0.0048 17.0 0.3 0.0076 16.4 0.3 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus GrpE PF01025.19 PSC76080.1 - 0.0089 15.7 5.1 0.018 14.7 4.3 1.8 1 1 1 2 2 2 1 GrpE Uso1_p115_C PF04871.13 PSC76080.1 - 0.011 16.1 7.8 0.022 15.1 7.8 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF4201 PF13870.6 PSC76080.1 - 0.015 15.0 1.3 0.029 14.1 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Rac1 PF09632.10 PSC76080.1 - 0.028 13.6 0.6 0.073 12.2 0.6 1.6 1 0 0 1 1 1 0 Rac1-binding domain ATG16 PF08614.11 PSC76080.1 - 0.045 14.0 6.6 0.076 13.2 6.6 1.3 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) Syntaxin PF00804.25 PSC76080.1 - 0.097 12.3 2.4 0.18 11.5 2.4 1.3 1 0 0 1 1 1 0 Syntaxin EzrA PF06160.12 PSC76080.1 - 0.1 10.7 1.3 0.16 10.1 1.3 1.2 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA Ubie_methyltran PF01209.18 PSC76080.1 - 0.11 11.9 0.0 0.39 10.0 0.0 1.9 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family OmpH PF03938.14 PSC76080.1 - 0.11 12.8 3.2 0.23 11.8 3.2 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Spc7 PF08317.11 PSC76080.1 - 0.12 11.3 2.8 0.17 10.7 2.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 PSC76080.1 - 0.12 12.5 3.1 0.34 11.1 3.1 1.8 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding TPR_MLP1_2 PF07926.12 PSC76080.1 - 0.15 12.1 8.2 0.17 11.9 6.7 1.9 2 0 0 2 2 1 0 TPR/MLP1/MLP2-like protein HAUS-augmin3 PF14932.6 PSC76080.1 - 0.18 11.3 3.9 0.3 10.6 3.9 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 Macoilin PF09726.9 PSC76080.1 - 0.18 10.3 2.0 0.23 10.0 2.0 1.1 1 0 0 1 1 1 0 Macoilin family Nsp1_C PF05064.13 PSC76080.1 - 0.2 11.5 1.5 0.36 10.7 1.5 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region PRKG1_interact PF15898.5 PSC76080.1 - 0.24 12.3 6.5 0.94 10.4 5.7 2.3 2 1 0 2 2 1 0 cGMP-dependent protein kinase interacting domain YabA PF06156.13 PSC76080.1 - 0.25 12.0 3.7 0.3 11.8 1.3 2.3 2 1 1 3 3 2 0 Initiation control protein YabA Golgin_A5 PF09787.9 PSC76080.1 - 0.25 10.8 3.4 0.42 10.0 3.4 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Jnk-SapK_ap_N PF09744.9 PSC76080.1 - 0.25 11.5 6.8 0.45 10.7 6.0 1.8 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 SHE3 PF17078.5 PSC76080.1 - 0.45 10.2 3.5 0.61 9.8 2.1 1.8 2 0 0 2 2 2 0 SWI5-dependent HO expression protein 3 SKA2 PF16740.5 PSC76080.1 - 0.49 10.2 5.5 0.48 10.2 3.5 2.0 2 0 0 2 2 1 0 Spindle and kinetochore-associated protein 2 Seryl_tRNA_N PF02403.22 PSC76080.1 - 0.69 10.2 4.1 1.3 9.3 4.1 1.4 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain bZIP_1 PF00170.21 PSC76080.1 - 1 9.5 4.8 8.6 6.5 0.4 2.6 1 1 1 2 2 2 0 bZIP transcription factor Cep57_CLD_2 PF14197.6 PSC76080.1 - 1.4 9.1 9.6 3.7 7.7 9.6 1.8 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 bZIP_2 PF07716.15 PSC76080.1 - 1.6 8.8 9.7 0.96 9.6 1.9 2.4 2 0 0 2 2 2 0 Basic region leucine zipper DivIC PF04977.15 PSC76080.1 - 1.7 8.5 10.6 6.9 6.5 2.9 2.7 2 1 1 3 3 2 0 Septum formation initiator Spc24 PF08286.11 PSC76080.1 - 2 8.7 5.4 24 5.2 5.5 2.2 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 HALZ PF02183.18 PSC76080.1 - 3.3 8.0 6.0 1.5 9.1 1.4 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper DUF4407 PF14362.6 PSC76080.1 - 4.1 6.7 12.0 0.3 10.4 7.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HalX PF08663.10 PSC76080.1 - 6.4 7.2 8.2 7 7.0 4.6 2.6 1 1 1 2 2 2 0 HalX domain Peptidase_S49 PF01343.18 PSC76081.1 - 3.2e-69 231.8 1.0 2.5e-43 147.7 0.5 2.5 2 0 0 2 2 2 2 Peptidase family S49 CLP_protease PF00574.23 PSC76081.1 - 0.00094 19.1 0.5 0.0051 16.7 0.2 2.2 2 0 0 2 2 2 1 Clp protease SDH_sah PF01972.16 PSC76081.1 - 0.0035 16.4 0.0 0.0054 15.8 0.0 1.2 1 0 0 1 1 1 1 Serine dehydrogenase proteinase ECH_1 PF00378.20 PSC76081.1 - 0.25 10.6 0.0 0.25 10.6 0.0 2.8 3 0 0 3 3 3 0 Enoyl-CoA hydratase/isomerase TipAS PF07739.13 PSC76081.1 - 0.9 10.1 9.0 0.81 10.3 0.1 3.3 3 0 0 3 3 3 0 TipAS antibiotic-recognition domain HAGH_C PF16123.5 PSC76082.1 - 1.4e-23 83.2 0.0 1.9e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 PSC76082.1 - 1.1e-16 61.5 4.8 5.1e-16 59.3 4.8 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PSC76082.1 - 0.019 14.5 0.4 0.03 13.8 0.2 1.6 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Ribosomal_L12_N PF16320.5 PSC76082.1 - 1.3 8.8 0.0 1.3 8.8 0.0 2.9 3 0 0 3 3 3 0 Ribosomal protein L7/L12 dimerisation domain Sulfate_transp PF00916.20 PSC76083.1 - 8.6e-43 146.5 9.0 3.3e-37 128.2 4.9 2.3 1 1 0 2 2 2 2 Sulfate permease family Glutaredoxin PF00462.24 PSC76083.1 - 5.2e-12 45.8 0.0 9.5e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin DSBA PF01323.20 PSC76083.1 - 0.021 14.6 0.1 0.26 11.1 0.0 2.2 1 1 1 2 2 2 0 DSBA-like thioredoxin domain COG6 PF06419.11 PSC76084.1 - 9.9e-177 588.9 0.0 1.3e-176 588.5 0.0 1.1 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 DUF1995 PF09353.10 PSC76084.1 - 2.9e-31 109.1 0.0 7.6e-31 107.7 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF1995) VSP PF03302.13 PSC76084.1 - 0.0014 17.5 40.2 0.0014 17.5 40.2 5.5 1 1 4 5 5 5 2 Giardia variant-specific surface protein FlgN PF05130.12 PSC76084.1 - 0.23 11.9 1.1 0.68 10.4 0.1 2.3 2 0 0 2 2 2 0 FlgN protein DUF3054 PF11255.8 PSC76085.1 - 3.7e-26 91.8 6.0 5.6e-26 91.2 6.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3054) Ephrin_rec_like PF07699.13 PSC76086.1 - 4.2e-56 186.5 177.3 2.4e-08 33.6 12.8 18.1 7 3 10 18 18 18 16 Putative ephrin-receptor like KDZ PF18758.1 PSC76086.1 - 7.5e-17 61.7 0.0 1.6e-16 60.6 0.0 1.5 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase TIP120 PF08623.10 PSC76087.1 - 6.8e-58 195.2 0.1 1.6e-55 187.4 0.0 4.0 4 1 1 5 5 5 1 TATA-binding protein interacting (TIP20) Alpha_kinase PF02816.18 PSC76087.1 - 3.4e-17 63.2 0.0 6.2e-17 62.3 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family HEAT_2 PF13646.6 PSC76087.1 - 4.5e-12 46.2 43.4 2.2e-05 24.7 2.0 9.6 8 1 3 11 11 11 6 HEAT repeats HEAT PF02985.22 PSC76087.1 - 6.7e-07 29.0 46.4 0.075 13.3 0.1 14.5 17 0 0 17 17 15 2 HEAT repeat TAF6_C PF07571.13 PSC76087.1 - 1.3e-05 25.4 0.8 0.01 16.1 0.0 5.3 6 2 1 7 7 7 1 TAF6 C-terminal HEAT repeat domain HEAT_EZ PF13513.6 PSC76087.1 - 0.00021 21.7 1.2 0.0091 16.5 0.2 12.5 10 4 4 14 14 12 2 HEAT-like repeat DUF3385 PF11865.8 PSC76087.1 - 0.00028 20.8 0.0 2.3 8.1 0.0 4.8 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) DNA_pol_phi PF04931.13 PSC76087.1 - 0.12 10.5 3.9 0.36 8.9 2.3 2.4 2 0 0 2 2 2 0 DNA polymerase phi MMS19_N PF14500.6 PSC76087.1 - 0.13 11.8 5.9 5.5 6.5 0.0 5.9 7 2 0 7 7 7 0 Dos2-interacting transcription regulator of RNA-Pol-II FerA PF08165.11 PSC76087.1 - 0.14 12.2 0.2 2.5 8.1 0.0 3.4 3 1 0 3 3 3 0 FerA (NUC095) domain RRN3 PF05327.11 PSC76087.1 - 0.25 9.9 0.1 0.95 7.9 0.1 1.8 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 V-ATPase_H_N PF03224.14 PSC76087.1 - 0.36 10.1 2.3 1.8 7.8 0.1 3.1 3 0 0 3 3 3 0 V-ATPase subunit H Se-cys_synth_N PF12390.8 PSC76087.1 - 7.1 6.9 7.6 14 6.0 0.1 4.9 3 0 0 3 3 3 0 Selenocysteine synthase N terminal TIP120 PF08623.10 PSC76088.1 - 4.6e-58 195.7 0.2 1.6e-55 187.5 0.0 4.2 4 1 0 5 5 5 1 TATA-binding protein interacting (TIP20) Alpha_kinase PF02816.18 PSC76088.1 - 3.3e-17 63.2 0.0 5.9e-17 62.4 0.0 1.4 1 0 0 1 1 1 1 Alpha-kinase family HEAT_2 PF13646.6 PSC76088.1 - 1.8e-12 47.4 45.6 2.7e-05 24.4 2.4 10.1 7 2 4 11 11 11 7 HEAT repeats HEAT PF02985.22 PSC76088.1 - 1.1e-06 28.4 47.5 0.073 13.4 0.1 14.6 17 0 0 17 17 15 2 HEAT repeat TAF6_C PF07571.13 PSC76088.1 - 1.1e-05 25.7 0.7 0.01 16.2 0.0 5.4 6 2 1 7 7 7 1 TAF6 C-terminal HEAT repeat domain DUF3385 PF11865.8 PSC76088.1 - 9.4e-05 22.4 0.0 2.2 8.2 0.0 4.8 5 0 0 5 5 5 1 Domain of unknown function (DUF3385) UME PF08064.13 PSC76088.1 - 0.00018 21.3 0.0 26 4.8 0.2 6.5 7 2 2 9 9 8 0 UME (NUC010) domain HEAT_EZ PF13513.6 PSC76088.1 - 0.00019 21.8 1.2 0.0089 16.5 0.2 12.6 9 5 6 15 15 13 3 HEAT-like repeat MMS19_N PF14500.6 PSC76088.1 - 0.011 15.3 9.6 4.5 6.8 1.8 5.7 6 2 0 6 6 6 0 Dos2-interacting transcription regulator of RNA-Pol-II RIX1 PF08167.12 PSC76088.1 - 0.072 12.8 0.0 6.9 6.4 0.0 3.5 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis FerA PF08165.11 PSC76088.1 - 0.11 12.5 0.2 2.5 8.1 0.0 3.6 3 1 0 3 3 3 0 FerA (NUC095) domain DNA_pol_phi PF04931.13 PSC76088.1 - 0.11 10.6 3.9 0.35 8.9 2.3 2.4 2 0 0 2 2 2 0 DNA polymerase phi RRN3 PF05327.11 PSC76088.1 - 0.2 10.1 0.1 0.92 8.0 0.1 2.0 2 0 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Xpo1 PF08389.12 PSC76088.1 - 0.22 11.6 0.0 17 5.4 0.0 3.8 4 1 1 5 5 5 0 Exportin 1-like protein V-ATPase_H_N PF03224.14 PSC76088.1 - 0.84 8.9 4.7 2.4 7.4 0.2 3.5 3 1 1 4 4 4 0 V-ATPase subunit H Se-cys_synth_N PF12390.8 PSC76088.1 - 6.1 7.2 7.6 13 6.1 0.1 5.0 3 0 0 3 3 3 0 Selenocysteine synthase N terminal DNA_pol_A_exo1 PF01612.20 PSC76089.1 - 1.4e-13 50.9 0.0 1.9e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 3'-5' exonuclease DUF2722 PF10846.8 PSC76090.1 - 3e-05 23.1 0.3 3e-05 23.1 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) SOGA PF11365.8 PSC76090.1 - 0.043 14.9 3.6 0.043 14.9 3.6 3.2 2 1 1 3 3 3 0 Protein SOGA PRC2_HTH_1 PF18118.1 PSC76090.1 - 0.073 13.9 4.5 0.86 10.4 0.0 2.4 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Rxt3 PF08642.10 PSC76090.1 - 0.1 13.4 5.3 3.7 8.4 0.9 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Ndc1_Nup PF09531.10 PSC76090.1 - 0.12 11.1 5.0 0.15 10.7 5.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Dicer_dimer PF03368.14 PSC76090.1 - 0.42 10.8 2.9 0.26 11.5 0.2 2.0 2 0 0 2 2 2 0 Dicer dimerisation domain DUF572 PF04502.13 PSC76090.1 - 3.6 7.1 13.4 5.1 6.6 13.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_C58 PF03543.14 PSC76090.1 - 5.4 6.7 20.3 1.5 8.5 3.5 2.3 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen PAT1 PF09770.9 PSC76090.1 - 5.5 5.1 22.6 7.8 4.6 22.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3371 PF11851.8 PSC76090.1 - 7.4 7.7 15.4 5.5 8.1 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) SRP-alpha_N PF04086.13 PSC76090.1 - 9.6 6.0 19.4 14 5.5 19.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2722 PF10846.8 PSC76091.1 - 3e-05 23.1 0.3 3e-05 23.1 0.3 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) SOGA PF11365.8 PSC76091.1 - 0.043 14.9 3.6 0.043 14.9 3.6 3.2 2 1 1 3 3 3 0 Protein SOGA PRC2_HTH_1 PF18118.1 PSC76091.1 - 0.073 13.9 4.5 0.86 10.4 0.0 2.4 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain Rxt3 PF08642.10 PSC76091.1 - 0.1 13.4 5.3 3.7 8.4 0.9 2.2 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Ndc1_Nup PF09531.10 PSC76091.1 - 0.12 11.1 5.0 0.15 10.7 5.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Dicer_dimer PF03368.14 PSC76091.1 - 0.42 10.8 2.9 0.26 11.5 0.2 2.0 2 0 0 2 2 2 0 Dicer dimerisation domain DUF572 PF04502.13 PSC76091.1 - 3.6 7.1 13.4 5.1 6.6 13.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Peptidase_C58 PF03543.14 PSC76091.1 - 5.4 6.7 20.3 1.5 8.5 3.5 2.3 2 0 0 2 2 2 0 Yersinia/Haemophilus virulence surface antigen PAT1 PF09770.9 PSC76091.1 - 5.5 5.1 22.6 7.8 4.6 22.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF3371 PF11851.8 PSC76091.1 - 7.4 7.7 15.4 5.5 8.1 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3371) SRP-alpha_N PF04086.13 PSC76091.1 - 9.6 6.0 19.4 14 5.5 19.4 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal RRM_2 PF04059.12 PSC76092.1 - 2.1e-32 111.2 0.1 3.5e-32 110.5 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif 2 Lipase_3 PF01764.25 PSC76092.1 - 4.2e-19 68.8 0.0 8.3e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) RRM_1 PF00076.22 PSC76092.1 - 0.00093 19.0 0.0 0.0019 18.0 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cytochrom_B_C PF00032.17 PSC76093.1 - 0.69 10.2 7.7 7.7 6.9 0.5 2.7 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD Lung_7-TM_R PF06814.13 PSC76093.1 - 6.2 6.0 10.5 0.85 8.8 0.3 2.7 3 0 0 3 3 3 0 Lung seven transmembrane receptor Peptidase_M24 PF00557.24 PSC76094.1 - 1.7e-61 207.6 0.0 2.1e-61 207.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 PSC76094.1 - 4.8e-30 103.8 0.0 7.5e-30 103.2 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain LcrG PF07216.12 PSC76094.1 - 0.041 13.8 0.1 0.52 10.3 0.0 2.5 3 0 0 3 3 3 0 LcrG protein MatE PF01554.18 PSC76095.1 - 4.1e-39 133.8 25.8 1.2e-23 83.6 10.0 2.3 2 0 0 2 2 2 2 MatE Ribosomal_S26e PF01283.19 PSC76095.1 - 2.5e-32 111.5 1.8 2.5e-32 111.5 1.8 1.8 2 0 0 2 2 2 1 Ribosomal protein S26e Polysacc_synt_C PF14667.6 PSC76095.1 - 1.5e-06 28.3 3.1 1.5e-06 28.3 3.1 3.3 3 1 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain DUF3311 PF11755.8 PSC76095.1 - 0.27 11.2 8.0 2.9 7.9 0.3 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3311) tRNA-synt_1e PF01406.19 PSC76096.1 - 8.4e-126 419.4 0.0 1.3e-100 336.7 0.0 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 PSC76096.1 - 5.7e-13 48.4 0.3 7.7e-06 24.9 0.1 2.1 2 0 0 2 2 2 2 tRNA synthetases class I (M) DALR_2 PF09190.11 PSC76096.1 - 2.8e-06 27.7 0.0 1.2e-05 25.7 0.0 2.1 1 0 0 1 1 1 1 DALR domain tRNA-synt_1f PF01921.18 PSC76096.1 - 1.7e-05 23.9 0.0 0.00075 18.5 0.0 2.1 2 0 0 2 2 2 1 tRNA synthetases class I (K) tRNA-synt_1 PF00133.22 PSC76096.1 - 2.9e-05 22.5 0.0 0.00018 19.9 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) ITI_HC_C PF06668.12 PSC76097.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus Maf PF02545.14 PSC76098.1 - 6.9e-18 65.0 4.7 1.3e-17 64.1 4.7 1.4 1 1 0 1 1 1 1 Maf-like protein PUD1_2 PF18457.1 PSC76098.1 - 0.16 11.9 0.2 0.2 11.6 0.2 1.2 1 0 0 1 1 1 0 Up-Regulated in long-lived daf-2 DUF3138 PF11336.8 PSC76098.1 - 1.1 7.8 11.3 1.2 7.6 11.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) Maf PF02545.14 PSC76099.1 - 1.2e-17 64.2 5.5 2.4e-17 63.3 5.5 1.4 1 1 0 1 1 1 1 Maf-like protein PUD1_2 PF18457.1 PSC76099.1 - 0.15 12.0 0.2 0.2 11.6 0.2 1.2 1 0 0 1 1 1 0 Up-Regulated in long-lived daf-2 DUF3138 PF11336.8 PSC76099.1 - 1.1 7.8 11.3 1.2 7.7 11.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) IBR PF01485.21 PSC76100.1 - 1.8e-13 50.5 32.9 2.7e-08 33.9 4.8 3.2 3 0 0 3 3 3 2 IBR domain, a half RING-finger domain TetR_C_32 PF09209.11 PSC76100.1 - 0.03 14.3 8.6 0.098 12.6 8.6 2.0 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain zf-CCCH PF00642.24 PSC76100.1 - 0.11 12.4 4.6 0.23 11.4 4.6 1.6 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) ER_lumen_recept PF00810.18 PSC76101.1 - 3.2e-34 118.9 3.3 5.4e-34 118.1 3.3 1.4 1 0 0 1 1 1 1 ER lumen protein retaining receptor FKBP_C PF00254.28 PSC76101.1 - 4.7e-18 65.3 0.0 7.8e-18 64.6 0.0 1.4 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase T2SSM PF04612.12 PSC76101.1 - 7.9 6.5 6.6 0.46 10.5 1.1 1.7 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein M adh_short PF00106.25 PSC76102.1 - 6e-17 61.8 0.3 2.4e-16 59.8 0.4 2.0 2 0 0 2 2 2 1 short chain dehydrogenase SH3_1 PF00018.28 PSC76102.1 - 4e-16 58.3 2.3 2.2e-07 30.3 0.0 2.7 3 0 0 3 3 3 2 SH3 domain SH3_9 PF14604.6 PSC76102.1 - 1.4e-15 56.9 0.9 5.7e-08 32.5 0.1 2.6 2 0 0 2 2 2 2 Variant SH3 domain adh_short_C2 PF13561.6 PSC76102.1 - 2.8e-09 36.9 1.0 2.8e-09 36.9 1.0 2.4 3 0 0 3 3 3 1 Enoyl-(Acyl carrier protein) reductase SH3_3 PF08239.11 PSC76102.1 - 1.9e-08 34.5 0.1 0.0015 18.8 0.0 2.5 2 0 0 2 2 2 2 Bacterial SH3 domain KR PF08659.10 PSC76102.1 - 6.7e-06 26.1 1.5 1.7e-05 24.8 1.5 1.7 1 0 0 1 1 1 1 KR domain ADH_zinc_N PF00107.26 PSC76102.1 - 0.11 12.5 1.6 0.36 10.8 1.6 2.0 1 0 0 1 1 1 0 Zinc-binding dehydrogenase SH3_4 PF06347.13 PSC76102.1 - 0.33 10.8 3.0 1.3 8.9 0.0 3.4 4 0 0 4 4 4 0 Bacterial SH3 domain RNA_pol_Rpb6 PF01192.22 PSC76104.1 - 4.9e-16 58.4 0.2 1.1e-15 57.3 0.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb6 Nucleotid_trans PF03407.16 PSC76104.1 - 1.3e-07 31.8 0.5 2.9e-07 30.7 0.5 1.5 1 1 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Mannosyl_trans3 PF11051.8 PSC76104.1 - 0.039 13.3 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative NPV_P10 PF05531.12 PSC76105.1 - 0.031 14.7 3.7 6.4 7.3 0.3 3.8 4 0 0 4 4 4 0 Nucleopolyhedrovirus P10 protein TolA_bind_tri PF16331.5 PSC76105.1 - 0.035 14.2 0.1 0.035 14.2 0.1 4.9 5 1 0 5 5 5 0 TolA binding protein trimerisation DUF4094 PF13334.6 PSC76105.1 - 0.07 13.5 0.7 0.07 13.5 0.7 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF4094) LPP PF04728.13 PSC76105.1 - 0.1 13.0 0.3 0.1 13.0 0.3 6.6 5 1 1 6 6 6 0 Lipoprotein leucine-zipper DUF4298 PF14131.6 PSC76105.1 - 1.5 8.8 10.9 0.2 11.7 2.0 3.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4298) Pentapeptide_2 PF01469.18 PSC76106.1 - 0.77 9.7 27.9 0.053 13.4 22.7 1.9 2 0 0 2 2 2 0 Pentapeptide repeats (8 copies) Mito_fiss_reg PF05308.11 PSC76106.1 - 1.1 9.3 10.9 0.99 9.4 0.8 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator Epimerase PF01370.21 PSC76107.1 - 4.5e-22 78.7 0.0 5.4e-20 71.9 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PSC76107.1 - 1.2e-13 51.3 0.1 3.9e-13 49.7 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 PSC76107.1 - 1.3e-11 44.5 0.0 2e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase NmrA PF05368.13 PSC76107.1 - 1.9e-06 27.6 0.0 2.8e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 PSC76107.1 - 2.1e-05 23.8 0.0 6.1e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain adh_short PF00106.25 PSC76107.1 - 0.00075 19.0 0.0 0.0019 17.7 0.0 1.8 1 0 0 1 1 1 1 short chain dehydrogenase 3Beta_HSD PF01073.19 PSC76107.1 - 0.00082 18.5 0.0 0.15 11.1 0.0 2.3 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 PSC76107.1 - 0.00089 19.2 0.0 0.0019 18.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Glyco_transf_4 PF13439.6 PSC76107.1 - 0.0028 17.7 0.0 0.0054 16.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyoxalase_4 PF13669.6 PSC76107.1 - 0.028 14.7 0.0 0.07 13.4 0.0 1.7 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Pyr_redox PF00070.27 PSC76107.1 - 0.18 12.4 0.0 1.8 9.2 0.0 2.3 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Clat_adaptor_s PF01217.20 PSC76108.1 - 2.5e-23 82.6 1.9 3.1e-23 82.3 1.9 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain FUSC PF04632.12 PSC76109.1 - 3.2 6.2 8.2 3.4 6.1 8.2 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF724 PF05266.14 PSC76110.1 - 0.0083 16.0 2.8 0.01 15.7 2.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF724) Dynamitin PF04912.14 PSC76110.1 - 0.015 14.6 3.1 0.016 14.5 3.1 1.1 1 0 0 1 1 1 0 Dynamitin APG6_N PF17675.1 PSC76110.1 - 0.026 15.0 7.7 0.033 14.7 7.7 1.2 1 0 0 1 1 1 0 Apg6 coiled-coil region CHD5 PF04420.14 PSC76110.1 - 0.043 13.7 0.0 0.047 13.6 0.0 1.1 1 0 0 1 1 1 0 CHD5-like protein CorA PF01544.18 PSC76110.1 - 0.065 12.5 2.4 0.071 12.4 2.4 1.1 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein Baculo_PEP_C PF04513.12 PSC76110.1 - 0.3 11.1 3.4 0.6 10.2 3.4 1.6 1 1 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus ATG16 PF08614.11 PSC76110.1 - 0.86 9.8 13.2 1.3 9.2 13.2 1.3 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) WXG100 PF06013.12 PSC76110.1 - 0.93 9.8 6.1 1.5 9.1 3.1 2.2 1 1 1 2 2 2 0 Proteins of 100 residues with WXG SKA2 PF16740.5 PSC76110.1 - 1.8 8.4 10.0 3.5 7.4 4.5 2.1 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 2 ERM PF00769.19 PSC76110.1 - 2.2 8.1 13.0 2.5 7.8 13.0 1.0 1 0 0 1 1 1 0 Ezrin/radixin/moesin family PGK PF00162.19 PSC76112.1 - 1.6e-162 540.8 0.1 2.1e-162 540.4 0.1 1.1 1 0 0 1 1 1 1 Phosphoglycerate kinase CLASP_N PF12348.8 PSC76112.1 - 0.047 13.3 0.4 3.5 7.1 0.2 2.2 1 1 1 2 2 2 0 CLASP N terminal ABC2_membrane PF01061.24 PSC76113.1 - 3.3e-31 108.4 24.0 3.3e-31 108.4 24.0 1.7 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 PSC76113.1 - 2e-22 80.2 0.0 3.7e-22 79.3 0.0 1.5 1 0 0 1 1 1 1 ABC transporter mTERF PF02536.14 PSC76113.1 - 1.6e-06 27.3 0.0 2.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 mTERF AAA_21 PF13304.6 PSC76113.1 - 0.00041 20.2 0.0 0.47 10.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 PSC76113.1 - 0.00047 19.4 21.9 0.00047 19.4 21.9 2.1 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_16 PF13191.6 PSC76113.1 - 0.015 15.7 0.1 0.038 14.4 0.1 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 PSC76113.1 - 0.038 14.5 0.0 0.079 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 PSC76113.1 - 0.05 13.2 0.0 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DNA_RNApol_7kD PF03604.13 PSC76114.1 - 1.2e-17 63.3 6.0 1.5e-17 63.0 6.0 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit DZR PF12773.7 PSC76114.1 - 0.0024 17.8 0.3 0.0031 17.5 0.3 1.2 1 0 0 1 1 1 1 Double zinc ribbon Rubredoxin_2 PF18073.1 PSC76114.1 - 0.0047 16.6 1.5 2.2 8.1 0.2 2.3 2 0 0 2 2 2 2 Rubredoxin metal binding domain HypA PF01155.19 PSC76114.1 - 0.019 15.0 0.2 0.022 14.8 0.2 1.1 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zinc_ribbon_13 PF09855.9 PSC76114.1 - 0.02 15.0 0.2 0.02 15.0 0.2 1.7 2 0 0 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) UPF0547 PF10571.9 PSC76114.1 - 0.025 14.7 2.6 0.28 11.3 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 PhnA_Zn_Ribbon PF08274.12 PSC76114.1 - 0.025 14.5 0.1 0.036 14.0 0.1 1.2 1 0 0 1 1 1 0 PhnA Zinc-Ribbon zf-ribbon_3 PF13248.6 PSC76114.1 - 0.041 13.3 2.5 0.2 11.1 2.3 2.0 1 1 1 2 2 2 0 zinc-ribbon domain Zn_ribbon_recom PF13408.6 PSC76114.1 - 0.043 14.3 4.2 0.62 10.6 0.9 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-Mss51 PF13824.6 PSC76114.1 - 0.1 12.7 2.3 0.78 9.9 0.2 2.1 1 1 1 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_2 PF13240.6 PSC76114.1 - 0.12 12.2 3.6 0.78 9.6 3.6 2.0 1 1 1 2 2 2 0 zinc-ribbon domain DUF1451 PF07295.11 PSC76114.1 - 0.15 12.1 0.2 0.17 11.9 0.2 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain OrfB_Zn_ribbon PF07282.11 PSC76114.1 - 0.15 12.0 1.6 0.19 11.6 1.2 1.3 1 1 0 1 1 1 0 Putative transposase DNA-binding domain Zn_ribbon_SprT PF17283.2 PSC76114.1 - 0.17 11.8 4.6 0.41 10.6 4.3 1.8 1 1 1 2 2 2 0 SprT-like zinc ribbon domain Zn-ribbon_8 PF09723.10 PSC76114.1 - 0.38 10.9 4.0 1.2 9.4 4.0 1.8 1 1 0 1 1 1 0 Zinc ribbon domain DUF647 PF04884.14 PSC76115.1 - 6.7e-82 274.7 1.3 6.7e-82 274.7 1.3 3.0 4 0 0 4 4 4 1 Vitamin B6 photo-protection and homoeostasis TFIIS_C PF01096.18 PSC76115.1 - 2.4e-15 56.1 1.3 2.4e-15 56.1 1.3 2.5 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 PSC76115.1 - 2.9e-10 39.9 3.2 2e-09 37.2 1.2 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Baculo_LEF5_C PF11792.8 PSC76115.1 - 0.0023 17.6 0.1 0.0051 16.5 0.1 1.6 1 0 0 1 1 1 1 Baculoviridae late expression factor 5 C-terminal domain LRR_4 PF12799.7 PSC76115.1 - 0.018 15.5 0.4 0.46 11.0 0.1 3.5 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) Anti-TRAP PF15777.5 PSC76115.1 - 0.024 14.6 0.1 0.098 12.6 0.1 2.0 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Spc29 PF17082.5 PSC76115.1 - 0.03 14.2 6.4 1.2 9.0 3.3 2.6 2 0 0 2 2 2 0 Spindle Pole Component 29 TDA11 PF17084.5 PSC76115.1 - 0.1 11.5 0.8 0.19 10.6 0.8 1.4 1 0 0 1 1 1 0 Topoisomerase I damage affected protein 11 zf-FPG_IleRS PF06827.14 PSC76115.1 - 0.14 12.0 0.1 0.4 10.6 0.1 1.8 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS LRR_8 PF13855.6 PSC76115.1 - 0.87 9.4 3.4 1 9.2 0.1 2.9 4 0 0 4 4 4 0 Leucine rich repeat DZR PF12773.7 PSC76115.1 - 4.2 7.5 4.7 1.7 8.8 0.4 2.2 2 0 0 2 2 2 0 Double zinc ribbon SIR2 PF02146.17 PSC76116.1 - 5.7e-22 78.5 0.0 1.3e-21 77.3 0.0 1.6 1 0 0 1 1 1 1 Sir2 family CpXC PF14353.6 PSC76116.1 - 0.28 11.2 1.6 1.3 9.1 0.2 2.7 2 0 0 2 2 2 0 CpXC protein Meth_synt_2 PF01717.18 PSC76117.1 - 2e-143 477.5 0.0 1.5e-139 464.8 0.0 2.4 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 PSC76117.1 - 9.5e-74 248.7 0.0 2.8e-65 220.9 0.0 2.2 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain DUF4575 PF15143.6 PSC76117.1 - 0.0045 17.2 0.3 0.046 13.9 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4575) DUF1707 PF08044.11 PSC76117.1 - 0.015 15.4 1.4 0.53 10.4 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) Meth_synt_2 PF01717.18 PSC76118.1 - 2.2e-143 477.4 0.0 1.5e-139 464.8 0.0 2.4 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 PSC76118.1 - 1.2e-72 245.1 0.0 3.7e-64 217.2 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, N-terminal domain DUF4575 PF15143.6 PSC76118.1 - 0.0046 17.2 0.3 0.046 13.9 0.1 2.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4575) DUF1707 PF08044.11 PSC76118.1 - 0.015 15.3 1.4 0.54 10.4 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1707) Plus-3 PF03126.18 PSC76119.1 - 1.3e-25 90.0 0.0 3.7e-25 88.6 0.0 1.8 1 0 0 1 1 1 1 Plus-3 domain NHL PF01436.21 PSC76119.1 - 2.1e-16 59.0 3.7 0.0018 18.2 0.0 5.7 6 0 0 6 6 6 3 NHL repeat SGL PF08450.12 PSC76119.1 - 3.5e-05 23.5 0.1 1.5 8.3 0.0 4.1 2 1 0 3 3 3 3 SMP-30/Gluconolactonase/LRE-like region DUF5128 PF17170.4 PSC76119.1 - 0.00053 19.2 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 6-bladed beta-propeller DNA_meth_N PF18284.1 PSC76119.1 - 0.078 12.9 0.2 0.18 11.7 0.2 1.7 1 0 0 1 1 1 0 DNA methylase N-terminal domain RVT_1 PF00078.27 PSC76120.1 - 1e-09 38.3 0.0 2.4e-07 30.5 0.0 3.0 1 1 1 2 2 2 2 Reverse transcriptase (RNA-dependent DNA polymerase) RNA_pol_Rpb8 PF03870.15 PSC76122.1 - 1e-52 178.0 0.3 1.1e-52 177.9 0.3 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 PSC76122.1 - 0.00038 20.5 0.6 0.011 15.8 0.1 2.1 2 0 0 2 2 2 2 DNA-directed RNA polymerase, subunit G GCN5L1 PF06320.13 PSC76123.1 - 0.15 12.2 0.0 0.15 12.2 0.0 3.3 3 1 0 3 3 3 0 GCN5-like protein 1 (GCN5L1) Defensin_propep PF00879.18 PSC76124.1 - 0.088 13.1 0.6 0.17 12.2 0.6 1.5 1 0 0 1 1 1 0 Defensin propeptide Haspin_kinase PF12330.8 PSC76125.1 - 0.049 12.6 0.0 0.073 12.0 0.0 1.1 1 0 0 1 1 1 0 Haspin like kinase domain Pkinase PF00069.25 PSC76125.1 - 0.17 11.2 0.0 0.36 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein kinase domain Lzipper-MIP1 PF14389.6 PSC76126.1 - 0.0076 16.5 3.9 0.0076 16.5 3.9 3.3 2 1 1 3 3 3 1 Leucine-zipper of ternary complex factor MIP1 GAS PF13851.6 PSC76126.1 - 0.2 11.0 36.1 0.13 11.6 17.9 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding YabA PF06156.13 PSC76126.1 - 0.27 11.9 21.6 1.8 9.2 7.0 3.2 2 1 1 3 3 3 0 Initiation control protein YabA Spc7 PF08317.11 PSC76126.1 - 0.5 9.2 36.7 0.25 10.2 17.3 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein TMF_TATA_bd PF12325.8 PSC76126.1 - 0.67 10.2 31.7 2.4 8.4 13.1 3.2 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding DUF4795 PF16043.5 PSC76126.1 - 0.93 9.1 25.4 1.4 8.4 25.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) DUF4665 PF15679.5 PSC76126.1 - 1.8 9.2 7.9 12 6.6 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4665) Leu_zip PF15294.6 PSC76126.1 - 2.8 7.4 27.7 0.76 9.2 15.1 2.1 1 1 1 2 2 2 0 Leucine zipper Lebercilin PF15619.6 PSC76126.1 - 3.6 7.2 37.0 3.7 7.2 8.6 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF4472 PF14739.6 PSC76126.1 - 3.9 8.3 32.6 2.7 8.7 6.5 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF4472) NHL PF01436.21 PSC76127.1 - 1.6e-30 103.5 3.7 5.1e-05 23.1 0.0 6.7 6 0 0 6 6 6 6 NHL repeat DUF3506 PF12014.8 PSC76127.1 - 1.2e-19 70.7 0.0 6.5e-18 65.1 0.0 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) SGL PF08450.12 PSC76127.1 - 6.2e-12 45.6 0.0 1.2e-08 34.8 0.0 2.9 3 1 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region DUF5128 PF17170.4 PSC76127.1 - 0.0053 16.0 0.0 0.066 12.4 0.0 2.0 2 0 0 2 2 2 1 6-bladed beta-propeller UPF0506 PF11703.8 PSC76127.1 - 0.083 13.3 4.9 0.16 12.4 4.9 1.5 1 0 0 1 1 1 0 UPF0506 UVR PF02151.19 PSC76127.1 - 9.2 6.2 26.7 0.45 10.3 5.2 3.1 3 0 0 3 3 3 0 UvrB/uvrC motif NHL PF01436.21 PSC76128.1 - 9.6e-32 107.4 1.7 4.9e-05 23.1 0.0 6.7 6 0 0 6 6 6 6 NHL repeat DUF3506 PF12014.8 PSC76128.1 - 1.1e-19 70.8 0.0 6.3e-18 65.1 0.0 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) SGL PF08450.12 PSC76128.1 - 6.4e-12 45.6 0.0 1.2e-08 34.9 0.0 2.9 3 1 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region DUF5128 PF17170.4 PSC76128.1 - 0.0013 18.0 0.0 0.016 14.4 0.0 2.0 2 0 0 2 2 2 1 6-bladed beta-propeller UPF0506 PF11703.8 PSC76128.1 - 0.08 13.3 4.9 0.16 12.4 4.9 1.5 1 0 0 1 1 1 0 UPF0506 UVR PF02151.19 PSC76128.1 - 8.6 6.3 26.7 0.43 10.4 5.2 3.1 3 0 0 3 3 3 0 UvrB/uvrC motif NHL PF01436.21 PSC76129.1 - 9.6e-32 107.4 1.7 4.9e-05 23.1 0.0 6.7 6 0 0 6 6 6 6 NHL repeat DUF3506 PF12014.8 PSC76129.1 - 1.1e-19 70.8 0.0 6.3e-18 65.1 0.0 2.8 1 1 0 1 1 1 1 Domain of unknown function (DUF3506) SGL PF08450.12 PSC76129.1 - 6.4e-12 45.6 0.0 1.2e-08 34.9 0.0 2.9 3 1 0 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region DUF5128 PF17170.4 PSC76129.1 - 0.0013 18.0 0.0 0.016 14.4 0.0 2.0 2 0 0 2 2 2 1 6-bladed beta-propeller UPF0506 PF11703.8 PSC76129.1 - 0.08 13.3 4.9 0.16 12.4 4.9 1.5 1 0 0 1 1 1 0 UPF0506 UVR PF02151.19 PSC76129.1 - 8.6 6.3 26.7 0.43 10.4 5.2 3.1 3 0 0 3 3 3 0 UvrB/uvrC motif Sulfotransfer_3 PF13469.6 PSC76130.1 - 1.1e-07 32.4 0.1 1.1e-07 32.4 0.1 7.0 3 3 2 5 5 5 2 Sulfotransferase family Sulfotransfer_1 PF00685.27 PSC76130.1 - 0.0019 17.7 0.0 0.031 13.8 0.0 2.4 1 1 0 1 1 1 1 Sulfotransferase domain Med28 PF11594.8 PSC76130.1 - 0.39 10.8 3.0 0.97 9.5 0.6 2.6 2 0 0 2 2 2 0 Mediator complex subunit 28 Ly49 PF08391.10 PSC76130.1 - 0.62 10.4 5.3 17 5.8 0.0 3.3 3 0 0 3 3 3 0 Ly49-like protein, N-terminal region Abhydrolase_1 PF00561.20 PSC76131.1 - 6.6e-14 52.2 0.1 3.3e-13 49.9 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 PSC76131.1 - 1.3e-12 48.8 17.4 1.3e-12 48.8 17.4 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PSC76131.1 - 8.9e-08 31.7 0.0 1.4e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 PSC76131.1 - 0.00083 19.1 0.0 0.0011 18.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase Thioesterase PF00975.20 PSC76131.1 - 0.001 19.3 0.0 0.0017 18.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_4 PF08386.10 PSC76131.1 - 0.0019 18.3 0.0 0.0088 16.1 0.0 1.9 2 0 0 2 2 2 1 TAP-like protein Abhydrolase_2 PF02230.16 PSC76131.1 - 0.013 15.3 0.0 0.1 12.4 0.0 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.18 PSC76131.1 - 0.039 13.5 0.0 1.6 8.3 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 PSC76131.1 - 0.2 11.1 0.1 17 4.8 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family CAAD PF14159.6 PSC76132.1 - 1.1e-29 102.1 0.1 2.9e-29 100.7 0.1 1.8 1 0 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase SNF2_N PF00176.23 PSC76132.1 - 7.2e-29 100.6 3.3 7.2e-29 100.6 3.3 2.5 2 1 0 2 2 2 1 SNF2 family N-terminal domain Ephrin_rec_like PF07699.13 PSC76132.1 - 1.3e-26 92.1 84.7 7.7e-06 25.6 8.7 9.9 1 1 9 10 10 10 9 Putative ephrin-receptor like Helicase_C PF00271.31 PSC76132.1 - 5e-09 36.5 0.0 1.3e-08 35.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC76132.1 - 3.1e-07 30.6 0.0 3.1e-07 30.6 0.0 2.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit TNFR_c6 PF00020.18 PSC76132.1 - 5.4 7.5 50.4 6.5 7.3 0.3 8.6 4 2 2 6 6 6 0 TNFR/NGFR cysteine-rich region sCache_3_2 PF17203.4 PSC76133.1 - 0.051 13.7 0.1 0.08 13.1 0.1 1.2 1 0 0 1 1 1 0 Single cache domain 3 Ank_2 PF12796.7 PSC76134.1 - 1.3e-18 67.4 2.1 2.5e-06 28.0 0.0 5.0 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC76134.1 - 1.6e-11 44.4 4.5 0.0033 18.0 0.1 6.0 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC76134.1 - 3.9e-09 36.0 4.6 2.2 9.1 0.1 7.8 8 0 0 8 8 7 3 Ankyrin repeat Ank_5 PF13857.6 PSC76134.1 - 9.2e-05 22.7 2.7 0.75 10.2 0.2 3.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) UvrD_C_2 PF13538.6 PSC76134.1 - 0.0047 16.7 0.0 0.029 14.2 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 PSC76134.1 - 0.02 14.3 0.0 0.13 11.6 0.0 2.1 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain ResIII PF04851.15 PSC76134.1 - 0.032 14.2 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PSC76134.1 - 0.035 14.4 3.5 4.1 7.7 0.0 3.9 3 0 0 3 3 2 0 AAA domain DEAD PF00270.29 PSC76134.1 - 0.099 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_19 PF13245.6 PSC76134.1 - 0.12 12.7 0.0 1.9 8.8 0.0 2.5 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 PSC76134.1 - 0.23 10.9 2.7 1 8.8 0.0 2.8 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain Ank PF00023.30 PSC76134.1 - 0.65 10.5 17.2 11 6.7 0.1 7.5 8 1 0 8 8 7 0 Ankyrin repeat TPR_2 PF07719.17 PSC76134.1 - 7.3 7.0 8.3 3.6 7.9 0.7 4.1 3 0 0 3 3 2 0 Tetratricopeptide repeat Ank_2 PF12796.7 PSC76135.1 - 1.2e-18 67.5 2.0 2.5e-06 28.0 0.0 5.0 3 1 1 4 4 4 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC76135.1 - 1.6e-11 44.5 4.5 0.0033 18.0 0.1 6.0 3 2 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC76135.1 - 3.9e-09 36.0 4.6 2.2 9.1 0.1 7.8 8 0 0 8 8 7 3 Ankyrin repeat Ank_5 PF13857.6 PSC76135.1 - 9.1e-05 22.7 2.7 0.75 10.2 0.2 3.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) UvrD_C_2 PF13538.6 PSC76135.1 - 0.0047 16.7 0.0 0.029 14.2 0.0 2.4 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain UvrD_C PF13361.6 PSC76135.1 - 0.02 14.3 0.0 0.13 11.6 0.0 2.1 1 1 1 2 2 2 0 UvrD-like helicase C-terminal domain ResIII PF04851.15 PSC76135.1 - 0.032 14.2 0.0 0.066 13.2 0.0 1.4 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PSC76135.1 - 0.035 14.4 3.5 4.1 7.7 0.0 3.9 3 0 0 3 3 2 0 AAA domain DEAD PF00270.29 PSC76135.1 - 0.099 12.4 0.0 0.2 11.4 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_19 PF13245.6 PSC76135.1 - 0.12 12.7 0.0 1.9 8.8 0.0 2.5 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 PSC76135.1 - 0.23 10.9 2.7 1 8.8 0.0 2.8 3 0 0 3 3 3 0 UvrD/REP helicase N-terminal domain Ank PF00023.30 PSC76135.1 - 0.53 10.8 17.0 11 6.7 0.1 7.6 8 1 0 8 8 7 0 Ankyrin repeat TPR_2 PF07719.17 PSC76135.1 - 7.3 7.0 8.3 3.6 7.9 0.7 4.1 3 0 0 3 3 2 0 Tetratricopeptide repeat rve PF00665.26 PSC76136.1 - 2.4e-18 66.5 0.0 4.7e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain GYF PF02213.16 PSC76136.1 - 0.00016 21.2 0.1 0.00029 20.4 0.1 1.4 1 0 0 1 1 1 1 GYF domain rve_3 PF13683.6 PSC76136.1 - 0.014 15.1 0.0 0.042 13.6 0.0 1.8 1 0 0 1 1 1 0 Integrase core domain SUIM_assoc PF16619.5 PSC76136.1 - 3.3 7.8 18.6 1.4 9.1 3.9 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 HTH_Tnp_Tc5 PF03221.16 PSC76137.1 - 1e-05 25.5 0.1 2.6e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain DDE_1 PF03184.19 PSC76137.1 - 0.00094 18.9 0.0 0.0021 17.7 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_17 PF12728.7 PSC76137.1 - 0.03 14.5 0.0 0.17 12.1 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain HTH_23 PF13384.6 PSC76137.1 - 0.065 13.1 0.1 0.065 13.1 0.1 3.4 3 0 0 3 3 3 0 Homeodomain-like domain DUF5384 PF17358.2 PSC76137.1 - 6.9 6.7 20.9 25 4.9 20.9 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5384) CBM_48 PF02922.18 PSC76138.1 - 6.8e-17 61.6 0.0 2.1e-16 60.1 0.0 1.9 2 0 0 2 2 2 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Alpha-amylase PF00128.24 PSC76138.1 - 1.5e-16 60.9 0.0 4.7e-11 42.9 0.0 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain NAD_binding_10 PF13460.6 PSC76139.1 - 1.2e-33 116.5 0.0 4.9e-33 114.6 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 PSC76139.1 - 1.2e-10 41.4 0.0 1.8e-10 40.8 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.21 PSC76139.1 - 8.8e-08 31.9 0.0 1.1e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 PSC76139.1 - 0.0001 21.8 0.4 0.00017 21.1 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_4 PF07993.12 PSC76139.1 - 0.00051 19.3 0.0 0.79 8.8 0.1 2.1 2 0 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 PSC76139.1 - 0.0061 15.7 0.0 0.031 13.4 0.1 1.9 2 0 0 2 2 2 1 RmlD substrate binding domain KR PF08659.10 PSC76139.1 - 0.011 15.7 0.5 0.022 14.7 0.4 1.6 2 0 0 2 2 2 0 KR domain 3Beta_HSD PF01073.19 PSC76139.1 - 0.014 14.4 0.0 0.018 14.0 0.0 1.1 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 PSC76139.1 - 0.026 13.9 0.0 0.03 13.7 0.0 1.1 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase TrkA_N PF02254.18 PSC76139.1 - 0.12 12.7 0.0 0.2 12.0 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Peripla_BP_2 PF01497.18 PSC76140.1 - 7.9e-10 38.7 0.0 7.9e-10 38.7 0.0 1.8 2 0 0 2 2 2 1 Periplasmic binding protein zf-MYND PF01753.18 PSC76140.1 - 1.6e-07 31.3 2.0 5.9e-07 29.5 2.0 2.0 1 0 0 1 1 1 1 MYND finger DUF2722 PF10846.8 PSC76140.1 - 0.00029 19.9 8.0 0.00029 19.9 8.0 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Suf PF05843.14 PSC76140.1 - 0.38 10.7 7.9 0.73 9.8 7.9 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Pex14_N PF04695.13 PSC76140.1 - 1.4 9.6 13.4 0.07 13.8 6.1 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF4746 PF15928.5 PSC76140.1 - 2.6 7.4 5.5 68 2.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) TERB2 PF15101.6 PSC76140.1 - 3 7.8 9.1 6.3 6.8 9.1 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Roughex PF06020.11 PSC76140.1 - 5 6.1 10.9 10 5.1 10.9 1.4 1 0 0 1 1 1 0 Drosophila roughex protein V_ATPase_I PF01496.19 PSC76141.1 - 7.1e-286 950.4 0.0 8.1e-286 950.2 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DHR10 PF18595.1 PSC76141.1 - 0.25 11.4 5.7 7.2 6.7 0.3 2.5 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain V_ATPase_I PF01496.19 PSC76142.1 - 1.8e-286 952.4 0.0 2e-286 952.2 0.0 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DHR10 PF18595.1 PSC76142.1 - 6.5 6.8 10.2 7.1 6.7 0.3 2.5 3 0 0 3 3 3 0 Designed helical repeat protein 10 domain zf-4CXXC_R1 PF10497.9 PSC76143.1 - 1.5e-26 92.5 13.7 3.2e-26 91.5 13.7 1.6 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 Adeno_E1A PF02703.14 PSC76143.1 - 0.022 14.3 1.3 0.047 13.3 1.3 1.4 1 0 0 1 1 1 0 Early E1A protein SUIM_assoc PF16619.5 PSC76143.1 - 1.6 8.8 10.1 0.081 13.0 3.1 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Ank_2 PF12796.7 PSC76146.1 - 4.1e-28 97.8 2.7 3.7e-11 43.5 0.0 3.8 3 1 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC76146.1 - 6.1e-18 65.0 1.9 1.4e-05 25.6 0.1 4.3 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC76146.1 - 3.3e-15 54.7 0.2 0.0068 16.8 0.0 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 PSC76146.1 - 1.5e-13 50.6 2.3 4.7e-06 26.8 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PSC76146.1 - 8.5e-12 45.0 5.1 0.00033 21.0 0.4 5.9 6 0 0 6 6 6 2 Ankyrin repeat cNMP_binding PF00027.29 PSC76146.1 - 2.4e-09 37.2 0.4 6.8e-09 35.7 0.4 1.9 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain Ion_trans PF00520.31 PSC76146.1 - 1.1e-07 31.4 14.1 1.6e-07 30.8 14.1 1.2 1 0 0 1 1 1 1 Ion transport protein Ion_trans_2 PF07885.16 PSC76146.1 - 3.5e-05 23.7 10.5 3.5e-05 23.7 10.5 2.4 1 1 1 2 2 2 1 Ion channel Ni_hydr_CYTB PF01292.20 PSC76146.1 - 0.014 15.0 0.3 0.047 13.3 0.3 1.9 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 Peptidase_C93 PF06035.11 PSC76146.1 - 0.12 12.2 0.0 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 Bacterial transglutaminase-like cysteine proteinase BTLCP Peptidase_M3 PF01432.20 PSC76147.1 - 2.7e-89 300.5 0.0 1.6e-73 248.5 0.0 2.1 2 0 0 2 2 2 2 Peptidase family M3 Peptidase_M50B PF13398.6 PSC76147.1 - 0.039 13.6 1.3 0.069 12.8 1.3 1.3 1 0 0 1 1 1 0 Peptidase M50B-like UBA_4 PF14555.6 PSC76148.1 - 0.00012 21.8 0.0 0.35 10.7 0.0 2.6 2 0 0 2 2 2 2 UBA-like domain Fasciclin PF02469.22 PSC76149.1 - 1.3e-22 80.4 0.1 2e-22 79.7 0.1 1.3 1 0 0 1 1 1 1 Fasciclin domain Methyltrans_SAM PF10672.9 PSC76149.1 - 3.6e-17 62.5 0.0 5.9e-17 61.7 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Methyltransf_31 PF13847.6 PSC76149.1 - 8e-11 42.0 0.0 1.9e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 PSC76149.1 - 1.9e-08 34.2 0.0 4.3e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Conserved hypothetical protein 95 PrmA PF06325.13 PSC76149.1 - 2e-07 30.7 0.3 3.6e-07 29.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 PSC76149.1 - 3.2e-07 30.1 0.0 5.8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 PSC76149.1 - 3.5e-07 30.8 0.0 1e-06 29.4 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain PUA_3 PF17785.1 PSC76149.1 - 3.7e-07 29.9 0.0 8.2e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 PUA-like domain Methyltransf_23 PF13489.6 PSC76149.1 - 0.002 18.0 0.0 0.0044 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.19 PSC76149.1 - 0.0026 17.9 0.5 0.0054 16.9 0.1 1.7 2 0 0 2 2 2 1 FtsJ-like methyltransferase N6_Mtase PF02384.16 PSC76149.1 - 0.014 14.7 0.0 0.02 14.2 0.0 1.1 1 0 0 1 1 1 0 N-6 DNA Methylase Methyltransf_11 PF08241.12 PSC76149.1 - 0.074 13.7 0.0 0.22 12.2 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain NapE PF06796.11 PSC76150.1 - 0.084 12.4 0.8 0.22 11.1 0.8 1.7 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE Rdx PF10262.9 PSC76151.1 - 8.1e-06 25.9 0.0 8.7e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Rdx family polyprenyl_synt PF00348.17 PSC76152.1 - 1.6e-70 237.1 0.0 2.1e-70 236.7 0.0 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase GYF_2 PF14237.6 PSC76153.1 - 2.5e-14 52.8 0.2 4.2e-14 52.1 0.2 1.4 1 0 0 1 1 1 1 GYF domain 2 GCP_N_terminal PF17681.1 PSC76155.1 - 4.5e-59 200.6 0.0 1.5e-58 198.8 0.0 1.9 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 PSC76155.1 - 5.9e-59 200.1 0.0 8.2e-59 199.6 0.0 1.2 1 0 0 1 1 1 1 Gamma tubulin complex component C-terminal HECT PF00632.25 PSC76156.1 - 2.5e-78 263.7 0.0 3.2e-78 263.3 0.0 1.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) RCC1 PF00415.18 PSC76156.1 - 3.6e-53 178.0 20.4 1.2e-12 48.2 0.8 6.1 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PSC76156.1 - 1.8e-28 97.7 37.5 1.3e-07 31.2 0.3 6.4 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat AzlD PF05437.12 PSC76156.1 - 0.031 14.4 1.4 0.05 13.8 0.4 2.0 2 0 0 2 2 2 0 Branched-chain amino acid transport protein (AzlD) Carb_anhydrase PF00194.21 PSC76157.1 - 2.3e-32 112.5 0.0 3e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Eukaryotic-type carbonic anhydrase ShK PF01549.24 PSC76158.1 - 1e-05 26.0 6.3 4.5e-05 23.9 6.3 2.3 1 0 0 1 1 1 1 ShK domain-like Choline_kinase PF01633.20 PSC76159.1 - 4.6e-44 150.5 0.0 6.2e-44 150.1 0.0 1.1 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 PSC76159.1 - 3.3e-09 37.0 5.8 1.2e-07 31.9 0.3 3.2 2 2 0 2 2 2 2 Phosphotransferase enzyme family 2OG-FeII_Oxy_3 PF13640.6 PSC76160.1 - 2.8e-11 44.2 0.0 9.4e-11 42.5 0.0 1.9 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 PSC76160.1 - 0.061 13.8 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily PLATZ PF04640.14 PSC76161.1 - 1.2e-17 64.3 6.9 1.2e-17 64.3 6.9 2.2 2 0 0 2 2 2 1 PLATZ transcription factor Sin_N PF04801.13 PSC76162.1 - 0.0027 17.0 4.2 0.0027 17.0 4.2 3.0 2 1 0 2 2 2 1 Sin-like protein conserved region JUPITER PF17054.5 PSC76162.1 - 0.093 12.2 0.7 0.25 10.8 0.0 1.8 2 0 0 2 2 2 0 Microtubule-Associated protein Jupiter ABC_membrane PF00664.23 PSC76163.1 - 1e-56 192.6 0.3 1.2e-30 107.1 0.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PSC76163.1 - 1.1e-43 149.1 0.0 5.3e-26 91.8 0.0 3.6 2 2 0 2 2 2 2 ABC transporter PRKCSH PF07915.13 PSC76163.1 - 4.4e-09 37.2 2.3 8.2e-09 36.4 2.3 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein AAA_21 PF13304.6 PSC76163.1 - 6e-09 36.1 0.1 0.039 13.8 0.1 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PSC76163.1 - 3.2e-08 33.3 0.0 0.0072 15.8 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PSC76163.1 - 1.2e-05 25.0 0.2 0.08 12.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 PSC76163.1 - 2.9e-05 24.3 0.8 1.6 9.0 0.0 3.8 3 0 0 3 3 3 2 AAA domain Dynamin_N PF00350.23 PSC76163.1 - 5.1e-05 23.4 0.1 0.25 11.4 0.0 2.4 2 0 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 PSC76163.1 - 0.00015 21.8 0.1 0.24 11.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 PSC76163.1 - 0.00059 20.3 8.6 0.23 11.8 0.1 4.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 PSC76163.1 - 0.002 18.6 0.0 2 8.8 0.0 2.2 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 PSC76163.1 - 0.0043 17.0 0.7 3.7 7.4 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase FtsK_SpoIIIE PF01580.18 PSC76163.1 - 0.0085 15.5 0.2 0.044 13.1 0.0 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family SbcCD_C PF13558.6 PSC76163.1 - 0.022 15.0 0.8 0.39 11.0 0.0 3.4 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 PSC76163.1 - 0.031 14.4 2.3 0.043 13.9 0.3 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain DUF815 PF05673.13 PSC76163.1 - 0.21 10.7 0.1 11 5.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.19 PSC76163.1 - 0.25 10.9 1.2 7.8 6.0 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ShK PF01549.24 PSC76163.1 - 0.44 11.1 5.6 1.9 9.1 5.6 2.2 1 1 0 1 1 1 0 ShK domain-like ABC_membrane PF00664.23 PSC76164.1 - 9.7e-57 192.7 0.3 1.2e-30 107.1 0.0 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PSC76164.1 - 9.6e-44 149.2 0.0 5.1e-26 91.8 0.0 3.7 2 2 0 2 2 2 2 ABC transporter PRKCSH PF07915.13 PSC76164.1 - 4.2e-09 37.3 2.3 7.9e-09 36.4 2.3 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein AAA_21 PF13304.6 PSC76164.1 - 5.3e-09 36.3 0.1 0.037 13.8 0.1 4.2 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 PSC76164.1 - 2.8e-08 33.5 0.0 0.0069 15.8 0.0 4.0 4 0 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 PSC76164.1 - 1.1e-05 25.1 0.2 0.077 12.7 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 PSC76164.1 - 2.6e-05 24.5 0.8 1.6 9.0 0.0 3.8 3 0 0 3 3 3 2 AAA domain Dynamin_N PF00350.23 PSC76164.1 - 4.7e-05 23.5 0.1 0.24 11.4 0.0 2.4 2 0 0 2 2 2 2 Dynamin family MMR_HSR1 PF01926.23 PSC76164.1 - 0.00014 21.9 0.1 0.24 11.5 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_16 PF13191.6 PSC76164.1 - 0.00049 20.5 8.5 0.22 11.9 0.1 4.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_23 PF13476.6 PSC76164.1 - 0.0019 18.7 0.0 2 8.9 0.0 2.2 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 PSC76164.1 - 0.004 17.1 0.7 3.6 7.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase FtsK_SpoIIIE PF01580.18 PSC76164.1 - 0.008 15.6 0.2 0.043 13.2 0.0 2.0 2 0 0 2 2 2 1 FtsK/SpoIIIE family SbcCD_C PF13558.6 PSC76164.1 - 0.02 15.1 0.8 0.38 11.0 0.0 3.5 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit DUF87 PF01935.17 PSC76164.1 - 0.029 14.4 2.3 0.041 14.0 0.3 2.0 2 0 0 2 2 2 0 Helicase HerA, central domain T2SSE PF00437.20 PSC76164.1 - 0.16 11.0 0.1 10 5.0 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein DUF815 PF05673.13 PSC76164.1 - 0.2 10.8 0.1 11 5.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) cobW PF02492.19 PSC76164.1 - 0.24 11.0 1.2 7.6 6.1 0.0 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ShK PF01549.24 PSC76164.1 - 0.42 11.2 5.6 1.9 9.1 5.6 2.2 1 1 0 1 1 1 0 ShK domain-like Apt1 PF10351.9 PSC76165.1 - 4.9e-29 101.5 0.0 1e-26 93.8 0.0 2.6 2 1 0 2 2 2 2 Golgi-body localisation protein domain Fmp27_GFWDK PF10347.9 PSC76165.1 - 3.1e-05 24.1 0.0 6.2e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 RNA pol II promoter Fmp27 protein domain Na_sulph_symp PF00939.19 PSC76166.1 - 5.7e-120 401.5 32.7 7.1e-120 401.2 32.7 1.0 1 0 0 1 1 1 1 Sodium:sulfate symporter transmembrane region CitMHS PF03600.16 PSC76166.1 - 3.4e-12 46.2 33.7 3.4e-12 46.2 33.7 2.6 1 1 2 3 3 3 2 Citrate transporter FWWh PF14922.6 PSC76166.1 - 0.16 11.9 0.0 0.33 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function Glyco_transf_90 PF05686.12 PSC76167.1 - 1.4e-17 63.7 0.1 1.5e-16 60.3 0.0 2.1 2 1 0 2 2 2 1 Glycosyl transferase family 90 Shadoo PF14999.6 PSC76167.1 - 0.016 15.3 4.5 0.016 15.3 4.5 1.9 3 0 0 3 3 3 0 Shadow of prion protein, neuroprotective DAOA PF15199.6 PSC76167.1 - 0.11 12.9 0.1 0.31 11.5 0.0 1.8 2 0 0 2 2 2 0 D-amino acid oxidase activator JHBP PF06585.11 PSC76167.1 - 0.21 10.7 0.0 0.39 9.9 0.0 1.3 1 0 0 1 1 1 0 Haemolymph juvenile hormone binding protein (JHBP) YGGT PF02325.17 PSC76168.1 - 8.3e-16 58.2 1.9 1.2e-15 57.6 1.9 1.3 1 0 0 1 1 1 1 YGGT family KleE PF17394.2 PSC76168.1 - 0.31 11.3 3.3 0.19 11.9 0.3 1.9 1 1 1 2 2 2 0 Uncharacterized KleE stable inheritance protein RskA PF10099.9 PSC76168.1 - 6.3 7.0 24.0 9.7 6.4 24.0 1.3 1 0 0 1 1 1 0 Anti-sigma-K factor rskA Sugar_tr PF00083.24 PSC76169.1 - 8e-115 384.3 27.9 1e-114 383.9 27.9 1.0 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 PSC76169.1 - 2.3e-13 49.8 33.6 2.3e-13 49.8 33.6 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Phage_holin_3_2 PF04550.12 PSC76169.1 - 5.4 7.6 14.3 0.032 14.8 3.9 2.8 3 1 0 3 3 3 0 Phage holin family 2 Hpt PF01627.23 PSC76170.1 - 1.2e-12 47.9 1.4 1.2e-12 47.9 1.4 1.8 2 0 0 2 2 2 1 Hpt domain Sec16_C PF12931.7 PSC76171.1 - 2.9e-11 43.6 0.4 8.2e-11 42.1 0.4 1.8 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.32 PSC76171.1 - 7.8e-08 32.9 7.2 0.2 12.6 0.3 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat SRA1 PF07304.11 PSC76171.1 - 3.1e-07 30.3 2.5 1.4e-06 28.1 0.0 2.6 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 PSC76171.1 - 0.24 11.5 0.0 0.82 9.7 0.0 1.8 2 0 0 2 2 2 0 Prp18 domain Sec16_C PF12931.7 PSC76172.1 - 2.9e-11 43.6 0.4 8.3e-11 42.1 0.4 1.8 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 WD40 PF00400.32 PSC76172.1 - 7.8e-08 32.9 7.2 0.2 12.6 0.3 5.6 5 0 0 5 5 5 2 WD domain, G-beta repeat SRA1 PF07304.11 PSC76172.1 - 2.6e-07 30.5 2.4 1.3e-06 28.2 0.0 2.6 2 0 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Prp18 PF02840.15 PSC76172.1 - 0.24 11.4 0.0 0.82 9.7 0.0 1.8 2 0 0 2 2 2 0 Prp18 domain Exostosin PF03016.15 PSC76174.1 - 1e-45 156.3 0.0 1.4e-45 155.8 0.0 1.2 1 0 0 1 1 1 1 Exostosin family EGF_2 PF07974.13 PSC76174.1 - 0.0027 18.0 19.9 0.0027 18.0 19.9 3.5 3 0 0 3 3 3 2 EGF-like domain TFIIA PF03153.13 PSC76175.1 - 2.1e-05 24.8 28.6 3.3e-05 24.1 28.6 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 PSC76175.1 - 0.026 14.7 0.7 0.045 13.9 0.7 1.3 1 0 0 1 1 1 0 DDHD domain DUF2722 PF10846.8 PSC76175.1 - 0.027 13.4 21.2 0.039 12.9 21.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) SpoIIP PF07454.11 PSC76175.1 - 0.14 11.6 5.0 0.21 11.0 5.0 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) EPL1 PF10513.9 PSC76175.1 - 0.28 11.6 4.8 0.49 10.8 4.8 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Rxt3 PF08642.10 PSC76175.1 - 0.35 11.7 1.0 0.63 10.8 1.0 1.3 1 0 0 1 1 1 0 Histone deacetylation protein Rxt3 ECM1 PF05782.11 PSC76175.1 - 1.4 7.7 15.7 2 7.2 15.7 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) eIF-3_zeta PF05091.12 PSC76175.1 - 3 6.7 12.1 4.3 6.2 12.1 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) RR_TM4-6 PF06459.12 PSC76175.1 - 3.1 7.6 6.7 4.8 6.9 6.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 PAT1 PF09770.9 PSC76175.1 - 3.5 5.8 21.6 4.9 5.3 21.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Presenilin PF01080.17 PSC76175.1 - 3.7 6.2 10.1 5.6 5.6 10.1 1.1 1 0 0 1 1 1 0 Presenilin Pex14_N PF04695.13 PSC76175.1 - 3.8 8.1 28.0 8.4 7.0 28.0 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3530 PF12048.8 PSC76175.1 - 4.5 6.6 28.4 0.071 12.5 20.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) BAF1_ABF1 PF04684.13 PSC76175.1 - 4.7 6.2 8.7 7.1 5.6 8.7 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CPSF100_C PF13299.6 PSC76175.1 - 4.7 7.4 5.9 8.5 6.5 5.9 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal V_ATPase_I PF01496.19 PSC76175.1 - 5.2 4.9 6.3 9.1 4.1 6.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ndc1_Nup PF09531.10 PSC76175.1 - 5.6 5.5 7.7 8.4 4.9 7.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.16 PSC76175.1 - 5.9 6.9 4.8 9.6 6.2 4.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EIIBC-GUT_N PF03612.14 PSC76175.1 - 9 6.0 6.9 16 5.2 6.9 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Ocnus PF05005.15 PSC76176.1 - 0.0003 20.9 0.0 0.00056 20.0 0.0 1.4 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) Coprogen_oxidas PF01218.18 PSC76177.1 - 4.8e-108 360.4 0.0 6.1e-108 360.0 0.0 1.1 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase SbcCD_C PF13558.6 PSC76177.1 - 0.014 15.6 1.5 0.034 14.4 1.5 1.7 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit Flavin_Reduct PF01613.18 PSC76178.1 - 3.1e-12 46.8 0.0 4.4e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 Flavin reductase like domain TGT PF01702.18 PSC76179.1 - 1.1e-78 264.8 0.0 1.8e-78 264.2 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase V_ATPase_I PF01496.19 PSC76179.1 - 0.29 9.0 13.8 0.43 8.4 13.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pkinase_fungal PF17667.1 PSC76179.1 - 0.64 8.7 3.5 1 8.0 3.5 1.2 1 0 0 1 1 1 0 Fungal protein kinase SKA1 PF07160.12 PSC76179.1 - 2.3 8.0 17.6 4.1 7.2 17.6 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 GREB1 PF15782.5 PSC76179.1 - 3.5 4.6 9.1 4.9 4.1 9.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer NPR1_interact PF15699.5 PSC76179.1 - 4.2 8.0 11.9 9.8 6.9 11.9 1.6 1 0 0 1 1 1 0 NPR1 interacting Thx PF17070.5 PSC76180.1 - 0.00074 19.5 4.4 0.0012 18.9 4.4 1.3 1 0 0 1 1 1 1 30S ribosomal protein Thx RPS31 PF17067.5 PSC76180.1 - 0.00084 19.5 0.3 0.0015 18.7 0.2 1.4 1 1 0 1 1 1 1 Ribosomal protein S31e Nucleo_LEF-12 PF06256.11 PSC76180.1 - 0.1 12.4 0.8 0.13 12.0 0.8 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus LEF-12 protein AZUL PF16558.5 PSC76180.1 - 2.6 8.4 12.8 19 5.6 12.8 2.3 1 1 0 1 1 1 0 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A MFS_1 PF07690.16 PSC76181.1 - 9.2e-21 74.1 34.7 9.2e-21 74.1 34.7 3.6 3 1 1 4 4 4 2 Major Facilitator Superfamily Ysc84 PF04366.12 PSC76181.1 - 5.7e-11 42.3 0.0 6.1e-10 38.9 0.0 2.5 3 0 0 3 3 3 1 Las17-binding protein actin regulator Rotamase PF00639.21 PSC76181.1 - 3.4e-06 27.9 0.0 7.5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 PSC76181.1 - 7.8e-05 23.2 0.0 0.00014 22.4 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain PRIMA1 PF16101.5 PSC76181.1 - 0.23 11.5 17.0 0.2 11.7 3.2 3.1 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 OATP PF03137.20 PSC76181.1 - 0.4 8.9 2.9 1.1 7.5 0.1 2.1 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Mito_fiss_reg PF05308.11 PSC76181.1 - 0.83 9.7 2.5 7.4 6.6 0.2 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator CAP_N PF01213.19 PSC76181.1 - 2 7.8 16.8 2 7.8 5.3 2.8 3 0 0 3 3 3 0 Adenylate cyclase associated (CAP) N terminal Amidohydro_3 PF07969.11 PSC76182.1 - 5.6e-79 266.8 19.4 1.1e-77 262.6 19.4 2.2 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_1 PF01979.20 PSC76182.1 - 1.2e-15 57.8 0.6 1.3e-12 47.7 0.4 3.2 2 1 0 2 2 2 2 Amidohydrolase family Dehydratase_MU PF02288.15 PSC76182.1 - 0.13 12.2 2.5 0.35 10.8 2.5 1.7 1 0 0 1 1 1 0 Dehydratase medium subunit TALPID3 PF15324.6 PSC76182.1 - 0.26 8.9 1.0 0.41 8.3 1.0 1.2 1 0 0 1 1 1 0 Hedgehog signalling target Spt20 PF12090.8 PSC76182.1 - 8.2 6.0 9.5 2.1 7.9 1.5 2.8 3 0 0 3 3 3 0 Spt20 family WD40 PF00400.32 PSC76183.1 - 6.8e-12 45.7 4.7 0.14 13.1 0.0 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat WD40 PF00400.32 PSC76184.1 - 4.5e-12 46.3 4.1 0.14 13.1 0.0 7.5 7 0 0 7 7 7 5 WD domain, G-beta repeat MMR_HSR1_Xtn PF16897.5 PSC76185.1 - 8.3e-42 141.5 0.7 1.5e-41 140.7 0.7 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 PSC76185.1 - 5.7e-20 71.5 0.0 1.9e-19 69.8 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase TGS PF02824.21 PSC76185.1 - 7.5e-19 67.5 0.0 1.5e-18 66.6 0.0 1.5 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 PSC76185.1 - 2.3e-10 40.2 0.0 4.2e-10 39.4 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 PSC76185.1 - 0.00029 20.9 0.0 0.38 10.8 0.0 2.7 1 1 0 2 2 2 2 Dynamin family RsgA_GTPase PF03193.16 PSC76185.1 - 0.061 13.2 0.2 2.1 8.2 0.0 2.7 2 1 0 2 2 2 0 RsgA GTPase AAA_28 PF13521.6 PSC76185.1 - 0.079 13.2 0.4 0.17 12.1 0.4 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 PSC76185.1 - 0.1 13.0 0.0 0.18 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain Biotin_lipoyl PF00364.22 PSC76186.1 - 3.4e-10 39.6 0.7 7.7e-10 38.5 0.5 1.7 1 1 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 PSC76186.1 - 0.0001 22.1 0.5 0.1 12.4 0.3 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like DEC-1_N PF04625.13 PSC76186.1 - 0.0011 18.1 0.6 0.0014 17.7 0.6 1.4 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region RnfC_N PF13375.6 PSC76186.1 - 0.0011 18.9 0.1 0.0021 18.0 0.1 1.5 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.6 PSC76186.1 - 0.012 16.3 0.4 0.097 13.4 0.1 2.4 2 0 0 2 2 2 0 HlyD family secretion protein GCV_H PF01597.19 PSC76186.1 - 0.022 14.6 0.1 0.041 13.8 0.1 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein SMC_Nse1 PF07574.13 PSC76186.1 - 0.023 14.6 0.1 0.033 14.1 0.1 1.2 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex HlyD_D23 PF16576.5 PSC76186.1 - 0.044 13.0 0.1 1.2 8.3 0.0 2.4 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion PYNP_C PF07831.13 PSC76186.1 - 0.06 13.0 1.1 0.16 11.6 0.3 2.0 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain YqfD PF06898.11 PSC76186.1 - 0.082 11.7 0.4 0.17 10.7 0.4 1.5 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Peptidase_M23 PF01551.22 PSC76186.1 - 0.13 12.4 0.3 0.34 11.1 0.2 1.7 1 1 0 1 1 1 0 Peptidase family M23 Biotin_lipoyl PF00364.22 PSC76187.1 - 3.2e-10 39.7 0.6 7.4e-10 38.5 0.4 1.7 1 1 0 1 1 1 1 Biotin-requiring enzyme Biotin_lipoyl_2 PF13533.6 PSC76187.1 - 9.3e-05 22.2 0.5 0.1 12.5 0.3 2.6 1 1 1 2 2 2 2 Biotin-lipoyl like DEC-1_N PF04625.13 PSC76187.1 - 0.001 18.2 0.6 0.0013 17.8 0.6 1.4 1 0 0 1 1 1 1 DEC-1 protein, N-terminal region RnfC_N PF13375.6 PSC76187.1 - 0.001 19.0 0.1 0.002 18.1 0.1 1.5 1 0 0 1 1 1 1 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.6 PSC76187.1 - 0.01 16.5 0.3 0.091 13.5 0.0 2.4 2 0 0 2 2 2 0 HlyD family secretion protein GCV_H PF01597.19 PSC76187.1 - 0.021 14.7 0.1 0.037 13.9 0.1 1.4 1 0 0 1 1 1 0 Glycine cleavage H-protein SMC_Nse1 PF07574.13 PSC76187.1 - 0.022 14.7 0.1 0.032 14.1 0.1 1.2 1 0 0 1 1 1 0 Nse1 non-SMC component of SMC5-6 complex HlyD_D23 PF16576.5 PSC76187.1 - 0.047 12.9 0.1 1.5 8.0 0.0 2.4 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion PYNP_C PF07831.13 PSC76187.1 - 0.057 13.1 1.1 0.16 11.6 0.3 2.0 2 0 0 2 2 2 0 Pyrimidine nucleoside phosphorylase C-terminal domain YqfD PF06898.11 PSC76187.1 - 0.079 11.8 0.4 0.17 10.7 0.4 1.5 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Peptidase_M23 PF01551.22 PSC76187.1 - 0.13 12.5 0.3 0.33 11.2 0.3 1.7 1 1 0 1 1 1 0 Peptidase family M23 FAD_binding_7 PF03441.14 PSC76188.1 - 2.9e-63 213.0 0.8 4.9e-63 212.3 0.8 1.3 1 0 0 1 1 1 1 FAD binding domain of DNA photolyase DNA_photolyase PF00875.18 PSC76188.1 - 1.1e-24 87.3 0.0 1.9e-24 86.5 0.0 1.4 1 0 0 1 1 1 1 DNA photolyase Peptidase_S10 PF00450.22 PSC76189.1 - 4.8e-79 266.7 0.0 6.1e-79 266.4 0.0 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Abhydrolase_6 PF12697.7 PSC76190.1 - 8.4e-23 82.1 1.0 8.4e-23 82.1 1.0 4.7 3 2 1 4 4 4 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PSC76190.1 - 1.3e-15 57.4 0.0 1.3e-14 54.1 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PSC76190.1 - 1.4e-15 57.7 3.0 1.6e-15 57.5 0.0 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold GATA PF00320.27 PSC76190.1 - 1.9e-05 24.2 44.7 0.0006 19.4 9.0 5.3 5 0 0 5 5 5 3 GATA zinc finger Abhydrolase_6 PF12697.7 PSC76191.1 - 8.4e-23 82.1 1.0 8.4e-23 82.1 1.0 4.7 3 2 1 4 4 4 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PSC76191.1 - 1.3e-15 57.4 0.0 1.3e-14 54.1 0.0 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PSC76191.1 - 1.4e-15 57.7 3.0 1.6e-15 57.5 0.0 2.7 2 1 0 2 2 2 1 alpha/beta hydrolase fold GATA PF00320.27 PSC76191.1 - 1.3e-05 24.7 43.6 0.0006 19.4 9.0 5.3 5 0 0 5 5 5 3 GATA zinc finger DUF2045 PF09741.9 PSC76192.1 - 2.3e-30 105.7 0.0 3.4e-30 105.2 0.0 1.2 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2045) Proteasome PF00227.26 PSC76193.1 - 2.4e-34 118.5 0.1 1.1e-33 116.4 0.1 1.7 1 1 0 1 1 1 1 Proteasome subunit Ribosomal_L31 PF01197.18 PSC76194.1 - 0.0012 19.1 0.0 0.0022 18.2 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L31 S1 PF00575.23 PSC76195.1 - 6.4e-12 45.6 1.1 4.1e-07 30.2 0.0 4.2 4 0 0 4 4 4 3 S1 RNA binding domain Exostosin PF03016.15 PSC76197.1 - 1.5e-50 172.1 0.7 3e-50 171.2 0.0 1.8 2 0 0 2 2 2 1 Exostosin family EGF_2 PF07974.13 PSC76197.1 - 4.9e-05 23.6 32.6 0.0002 21.6 8.9 4.3 4 0 0 4 4 4 2 EGF-like domain SUIM_assoc PF16619.5 PSC76197.1 - 0.0035 17.4 2.8 0.0035 17.4 2.8 2.6 2 0 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 TPR_1 PF00515.28 PSC76197.1 - 0.0037 17.0 0.7 0.42 10.5 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TFIIA PF03153.13 PSC76197.1 - 0.027 14.5 15.0 0.14 12.1 6.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4677 PF15726.5 PSC76197.1 - 0.085 13.0 0.5 0.3 11.2 0.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4677) TPR_2 PF07719.17 PSC76197.1 - 0.13 12.4 0.6 4.5 7.6 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat BAT2_N PF07001.11 PSC76197.1 - 0.67 10.4 9.2 0.7 10.3 1.5 2.4 2 0 0 2 2 2 0 BAT2 N-terminus CPSF100_C PF13299.6 PSC76197.1 - 0.98 9.6 5.8 5.7 7.1 0.3 2.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal PK PF00224.21 PSC76198.1 - 2e-71 240.7 0.1 2.8e-71 240.2 0.1 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 PSC76198.1 - 2.8e-19 69.5 0.2 8e-19 68.0 0.2 1.8 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain DUF562 PF04763.12 PSC76198.1 - 0.13 11.7 0.2 0.26 10.7 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF562) ParBc PF02195.18 PSC76199.1 - 1.3e-13 51.0 0.0 2e-13 50.5 0.0 1.2 1 0 0 1 1 1 1 ParB-like nuclease domain HAD_2 PF13419.6 PSC76200.1 - 9e-19 68.2 0.0 1.4e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 PSC76200.1 - 1.3e-15 58.3 0.0 2e-15 57.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PSC76200.1 - 1.9e-07 31.0 0.1 9.1e-07 28.9 0.1 2.2 2 0 0 2 2 2 1 HAD-hyrolase-like HAD PF12710.7 PSC76200.1 - 8.4e-05 23.1 0.0 0.00029 21.3 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase NTP_transf_3 PF12804.7 PSC76200.1 - 0.0069 16.8 0.5 0.0069 16.8 0.5 2.4 2 1 0 2 2 2 1 MobA-like NTP transferase domain LisH_2 PF16045.5 PSC76201.1 - 7.7e-08 31.2 2.7 1.9e-07 30.0 0.1 2.3 2 0 0 2 2 2 1 LisH JIP_LZII PF16471.5 PSC76201.1 - 0.1 12.8 10.3 3.4 7.9 2.4 3.8 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II HsbA PF12296.8 PSC76201.1 - 0.79 10.2 17.7 2.1 8.8 1.2 4.4 3 1 1 4 4 4 0 Hydrophobic surface binding protein A rve PF00665.26 PSC76202.1 - 1.8e-18 66.8 0.0 4e-18 65.7 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC76202.1 - 0.015 15.1 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Integrase core domain AAA_25 PF13481.6 PSC76202.1 - 0.18 11.4 2.6 5.4 6.5 0.3 3.2 2 1 0 2 2 2 0 AAA domain Arm PF00514.23 PSC76203.1 - 4.2e-23 80.6 44.6 0.00046 20.1 0.1 12.6 13 0 0 13 13 13 9 Armadillo/beta-catenin-like repeat MatE PF01554.18 PSC76203.1 - 1.1e-16 60.9 8.6 1.1e-16 60.9 8.6 4.3 4 1 1 5 5 5 1 MatE HEAT PF02985.22 PSC76203.1 - 8.3e-11 41.2 42.5 0.00081 19.4 0.2 10.8 12 0 0 12 12 10 4 HEAT repeat HEAT_EZ PF13513.6 PSC76203.1 - 1.5e-08 34.9 59.0 0.017 15.7 1.1 10.5 8 2 2 10 10 10 4 HEAT-like repeat Cnd1 PF12717.7 PSC76203.1 - 4.7e-08 33.2 0.1 0.44 10.6 0.0 4.8 5 0 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Polysacc_synt_C PF14667.6 PSC76203.1 - 6.3e-07 29.6 5.1 6.3e-07 29.6 5.1 3.5 2 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain HEAT_2 PF13646.6 PSC76203.1 - 5e-05 23.6 51.6 0.043 14.2 9.3 8.4 1 1 10 11 11 11 5 HEAT repeats Atx10homo_assoc PF09759.9 PSC76203.1 - 0.00022 21.2 0.0 2.9 7.9 0.0 5.1 6 1 0 6 6 6 1 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 PSC76203.1 - 0.00028 20.8 0.1 1.5 8.8 0.1 4.2 3 1 1 4 4 4 1 Domain of unknown function (DUF3361) RTP1_C1 PF10363.9 PSC76203.1 - 0.001 19.2 0.6 2.3 8.4 0.0 3.6 3 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 PSC76203.1 - 0.0058 15.2 0.5 4.1 5.8 0.3 3.9 2 1 2 4 4 4 1 Adaptin N terminal region Arm_2 PF04826.13 PSC76203.1 - 0.04 13.4 0.0 3.7 6.9 0.0 3.3 3 1 0 3 3 3 0 Armadillo-like CLASP_N PF12348.8 PSC76203.1 - 0.15 11.6 0.1 43 3.6 0.0 3.2 3 0 0 3 3 3 0 CLASP N terminal Arm PF00514.23 PSC76204.1 - 4e-23 80.7 44.6 0.00046 20.1 0.1 12.6 13 0 0 13 13 13 9 Armadillo/beta-catenin-like repeat MatE PF01554.18 PSC76204.1 - 1.1e-16 60.9 8.6 1.1e-16 60.9 8.6 4.2 4 1 1 5 5 5 1 MatE HEAT PF02985.22 PSC76204.1 - 7.8e-11 41.3 42.5 0.00081 19.4 0.2 10.8 12 0 0 12 12 10 4 HEAT repeat HEAT_EZ PF13513.6 PSC76204.1 - 1.5e-08 34.9 59.0 0.017 15.7 1.1 10.4 8 2 2 10 10 10 4 HEAT-like repeat Cnd1 PF12717.7 PSC76204.1 - 4.7e-08 33.2 0.1 0.44 10.6 0.0 4.8 5 0 0 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Polysacc_synt_C PF14667.6 PSC76204.1 - 5.2e-06 26.6 8.3 5.2e-06 26.6 8.3 3.9 2 1 0 3 3 3 1 Polysaccharide biosynthesis C-terminal domain HEAT_2 PF13646.6 PSC76204.1 - 3.9e-05 24.0 51.3 0.041 14.3 9.2 8.4 1 1 9 10 10 10 5 HEAT repeats Atx10homo_assoc PF09759.9 PSC76204.1 - 0.00021 21.2 0.0 2.9 8.0 0.0 5.1 6 1 0 6 6 6 1 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 PSC76204.1 - 0.00028 20.9 0.1 1.5 8.8 0.1 4.2 3 1 1 4 4 4 1 Domain of unknown function (DUF3361) RTP1_C1 PF10363.9 PSC76204.1 - 0.001 19.2 0.6 2.3 8.5 0.0 3.6 3 1 0 3 3 3 2 Required for nuclear transport of RNA pol II C-terminus 1 Adaptin_N PF01602.20 PSC76204.1 - 0.0055 15.3 0.5 4.1 5.9 0.3 3.9 2 1 2 4 4 4 1 Adaptin N terminal region Arm_2 PF04826.13 PSC76204.1 - 0.039 13.4 0.0 3.7 6.9 0.0 3.3 3 1 0 3 3 3 0 Armadillo-like CLASP_N PF12348.8 PSC76204.1 - 0.15 11.6 0.1 43 3.6 0.0 3.2 3 0 0 3 3 3 0 CLASP N terminal Hist_deacetyl PF00850.19 PSC76205.1 - 8.5e-78 261.9 0.0 1.2e-77 261.5 0.0 1.2 1 0 0 1 1 1 1 Histone deacetylase domain zf-C3HC4_3 PF13920.6 PSC76205.1 - 0.023 14.6 10.7 0.043 13.7 10.7 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC76205.1 - 2.5 8.0 12.4 5.2 7.0 12.4 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 PSC76205.1 - 8.2 6.4 12.5 23 4.9 12.5 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) ALAD PF00490.21 PSC76206.1 - 1.9e-129 431.4 0.0 2.2e-129 431.2 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase CAP_N PF01213.19 PSC76207.1 - 2.1e-73 247.6 0.8 5.1e-73 246.3 0.0 2.1 1 1 1 2 2 2 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 PSC76207.1 - 2.3e-55 186.5 0.0 3.4e-55 186.0 0.0 1.2 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal Peptidase_S9 PF00326.21 PSC76207.1 - 8.4e-45 152.8 0.0 1.5e-44 152.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DLH PF01738.18 PSC76207.1 - 7.7e-06 25.6 0.1 1.9e-05 24.3 0.1 1.6 1 1 0 1 1 1 1 Dienelactone hydrolase family PD40 PF07676.12 PSC76207.1 - 0.00083 19.2 1.4 0.084 12.8 0.0 2.7 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat TBCC PF07986.12 PSC76207.1 - 0.019 14.7 2.2 0.5 10.1 2.7 2.2 1 1 1 2 2 2 0 Tubulin binding cofactor C Hydrolase_4 PF12146.8 PSC76207.1 - 0.048 12.9 0.1 0.68 9.2 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 PSC76207.1 - 0.05 13.2 0.0 0.11 12.0 0.0 1.6 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) AXE1 PF05448.12 PSC76207.1 - 0.14 10.9 0.1 4 6.0 0.1 2.6 3 0 0 3 3 3 0 Acetyl xylan esterase (AXE1) MinE PF03776.14 PSC76208.1 - 3.6e-12 46.1 0.2 6.3e-12 45.3 0.2 1.3 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE DUF1995 PF09353.10 PSC76209.1 - 8.2e-43 146.7 0.3 1.3e-42 146.1 0.0 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1995) Pectate_lyase_3 PF12708.7 PSC76210.1 - 0.00024 21.0 4.0 0.00091 19.1 0.0 2.4 2 1 0 2 2 2 1 Pectate lyase superfamily protein SBP PF03110.14 PSC76211.1 - 2.4e-14 53.4 5.0 5.1e-14 52.3 5.0 1.6 1 0 0 1 1 1 1 SBP domain SLD5_C PF16922.5 PSC76212.1 - 9.5e-20 70.6 0.2 1.9e-19 69.6 0.2 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 PSC76212.1 - 1.3e-06 28.9 2.0 2.7e-06 27.8 2.0 1.6 1 0 0 1 1 1 1 GINS complex protein Cupin_3 PF05899.12 PSC76212.1 - 0.14 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF861) MnmE_helical PF12631.7 PSC76212.1 - 0.18 11.9 0.7 0.36 11.0 0.8 1.4 1 1 0 1 1 1 0 MnmE helical domain GTP_EFTU PF00009.27 PSC76213.1 - 2.2e-51 174.2 0.0 3.3e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 PSC76213.1 - 3.4e-46 155.8 1.2 5.2e-46 155.2 1.2 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus Peptidase_S8 PF00082.22 PSC76213.1 - 1.1e-32 113.5 2.5 2.3e-32 112.5 2.5 1.5 1 0 0 1 1 1 1 Subtilase family EFG_C PF00679.24 PSC76213.1 - 2.4e-19 69.1 0.0 4.3e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PSC76213.1 - 1.6e-05 25.2 0.1 3.1e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PSC76213.1 - 0.00016 21.7 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 PSC76213.1 - 0.0042 16.6 0.0 0.0071 15.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 PSC76213.1 - 0.011 15.4 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Ras family RF3_C PF16658.5 PSC76213.1 - 0.023 14.5 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 PSC76213.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.7 1 1 0 1 1 1 0 Elongation Factor G, domain II PAN_4 PF14295.6 PSC76213.1 - 0.13 12.2 0.6 6 6.9 0.2 2.9 2 0 0 2 2 2 0 PAN domain GTP_EFTU PF00009.27 PSC76214.1 - 2.2e-51 174.2 0.0 3.3e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 PSC76214.1 - 3.4e-46 155.8 1.2 5.1e-46 155.2 1.2 1.3 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus Peptidase_S8 PF00082.22 PSC76214.1 - 3.9e-34 118.3 3.1 7.8e-34 117.3 3.1 1.5 1 0 0 1 1 1 1 Subtilase family EFG_C PF00679.24 PSC76214.1 - 2.4e-19 69.2 0.0 4.3e-19 68.3 0.0 1.4 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 PSC76214.1 - 1.6e-05 25.2 0.1 3.1e-05 24.3 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PSC76214.1 - 0.00016 21.7 0.0 0.00029 20.9 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 PSC76214.1 - 0.0041 16.6 0.0 0.0071 15.8 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 PSC76214.1 - 0.01 15.4 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Ras family RF3_C PF16658.5 PSC76214.1 - 0.023 14.5 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 Class II release factor RF3, C-terminal domain EFG_II PF14492.6 PSC76214.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.7 1 1 0 1 1 1 0 Elongation Factor G, domain II PAN_4 PF14295.6 PSC76214.1 - 0.13 12.2 0.6 6 6.9 0.2 2.9 2 0 0 2 2 2 0 PAN domain VSP PF03302.13 PSC76215.1 - 0.0089 14.9 205.2 0.22 10.3 26.8 6.0 2 2 3 5 5 5 5 Giardia variant-specific surface protein VSP PF03302.13 PSC76216.1 - 0.01 14.7 204.5 1.6 7.5 73.3 6.0 2 2 4 6 6 6 0 Giardia variant-specific surface protein SRP_SPB PF02978.19 PSC76217.1 - 5.1e-07 30.2 0.0 9.5e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Signal peptide binding domain DUF5372 PF17342.2 PSC76218.1 - 0.0013 19.1 0.1 1.7 9.1 0.0 2.6 2 0 0 2 2 2 2 Family of unknown function (DUF5372) TruB_C PF09142.11 PSC76218.1 - 0.011 15.5 5.5 0.61 9.9 0.4 3.1 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal FAM163 PF15069.6 PSC76218.1 - 3.3 8.1 6.7 1.1 9.7 0.1 2.8 3 0 0 3 3 3 0 FAM163 family DUF5372 PF17342.2 PSC76219.1 - 0.0013 19.1 0.1 1.7 9.1 0.0 2.6 2 0 0 2 2 2 2 Family of unknown function (DUF5372) TruB_C PF09142.11 PSC76219.1 - 0.011 15.5 5.5 0.61 9.9 0.4 3.1 2 0 0 2 2 2 0 tRNA Pseudouridine synthase II, C terminal FAM163 PF15069.6 PSC76219.1 - 3.3 8.1 6.7 1.1 9.7 0.1 2.8 3 0 0 3 3 3 0 FAM163 family Herpes_gE PF02480.16 PSC76221.1 - 0.26 10.0 0.5 1 8.0 0.0 1.9 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Pkinase PF00069.25 PSC76222.1 - 2.2e-32 112.5 0.0 9.4e-32 110.4 0.0 2.0 1 1 0 1 1 1 1 Protein kinase domain JAB PF01398.21 PSC76222.1 - 8.6e-29 99.9 0.1 1.4e-28 99.3 0.1 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Pkinase_Tyr PF07714.17 PSC76222.1 - 5.8e-21 74.9 0.0 3.3e-20 72.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase CSN5_C PF18323.1 PSC76222.1 - 3.9e-16 59.7 0.0 8.6e-16 58.6 0.0 1.6 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 PSC76222.1 - 2.3e-05 24.2 0.0 4.5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 PSC76222.1 - 0.01 15.9 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0172) OSR1_C PF12202.8 PSC76222.1 - 0.011 15.9 0.0 0.023 14.9 0.0 1.5 1 0 0 1 1 1 0 Oxidative-stress-responsive kinase 1 C-terminal domain Bax1-I PF01027.20 PSC76223.1 - 8.4e-41 140.1 17.5 1e-40 139.8 17.5 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Kinocilin PF15033.6 PSC76223.1 - 0.064 12.9 0.9 0.12 12.0 0.2 1.8 2 0 0 2 2 2 0 Kinocilin protein Bax1-I PF01027.20 PSC76224.1 - 1.9e-45 155.2 15.8 2.3e-45 155.0 15.8 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Kinocilin PF15033.6 PSC76224.1 - 0.05 13.3 0.9 0.078 12.6 0.2 1.6 2 0 0 2 2 2 0 Kinocilin protein DUF2715 PF10895.8 PSC76224.1 - 0.2 11.3 0.7 0.54 9.9 0.1 1.8 1 1 0 2 2 2 0 Domain of unknown function (DUF2715) Retrotran_gag_2 PF14223.6 PSC76225.1 - 1.6e-52 176.8 0.0 6.3e-25 87.5 0.0 2.1 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 PSC76225.1 - 1.4e-13 50.1 0.1 2.2e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 PSC76225.1 - 1.1e-06 28.4 0.0 0.06 13.2 0.0 2.3 2 0 0 2 2 2 2 gag-polypeptide of LTR copia-type Homez PF11569.8 PSC76225.1 - 0.0053 16.2 0.0 5.4 6.6 0.0 2.7 2 0 0 2 2 2 2 Homeodomain leucine-zipper encoding, Homez STAT1_TAZ2bind PF12162.8 PSC76225.1 - 0.015 14.9 0.1 7.8 6.2 0.0 2.5 2 0 0 2 2 2 0 STAT1 TAZ2 binding domain Hs1pro-1_N PF07231.12 PSC76225.1 - 0.025 14.3 0.3 14 5.4 0.0 2.7 2 2 0 2 2 2 0 Hs1pro-1 N-terminus Pre-PUA PF17832.1 PSC76225.1 - 0.047 14.4 0.0 23 5.8 0.0 2.7 2 0 0 2 2 2 0 Pre-PUA-like domain Retrotran_gag_2 PF14223.6 PSC76226.1 - 1e-157 517.6 0.1 3.8e-24 84.9 0.0 6.1 6 0 0 6 6 6 6 gag-polypeptide of LTR copia-type DUF4219 PF13961.6 PSC76226.1 - 4.8e-41 137.7 3.9 7.7e-05 22.3 0.0 6.3 6 0 0 6 6 6 6 Domain of unknown function (DUF4219) Retrotran_gag_3 PF14244.6 PSC76226.1 - 9.7e-22 76.5 0.1 0.22 11.3 0.0 6.3 6 0 0 6 6 6 6 gag-polypeptide of LTR copia-type Homez PF11569.8 PSC76226.1 - 4e-10 39.0 0.0 19 4.8 0.0 6.6 6 0 0 6 6 6 0 Homeodomain leucine-zipper encoding, Homez STAT1_TAZ2bind PF12162.8 PSC76226.1 - 3.8e-08 32.7 3.8 26 4.5 0.0 6.4 6 0 0 6 6 6 0 STAT1 TAZ2 binding domain Pre-PUA PF17832.1 PSC76226.1 - 8.6e-08 32.8 0.4 90 3.9 0.0 6.6 6 0 0 6 6 6 0 Pre-PUA-like domain Hs1pro-1_N PF07231.12 PSC76226.1 - 3.7e-07 30.1 2.9 43 3.8 0.0 6.6 6 0 0 6 6 6 0 Hs1pro-1 N-terminus Glyco_hydro_65C PF03633.15 PSC76226.1 - 2.4e-05 24.2 0.0 1.5e+02 2.4 0.0 6.1 6 0 0 6 6 6 0 Glycosyl hydrolase family 65, C-terminal domain DUF3939 PF13075.6 PSC76226.1 - 0.0007 19.6 0.0 2e+02 2.0 0.0 5.6 6 0 0 6 6 6 0 Protein of unknown function (DUF3939) Toxin_5 PF05294.13 PSC76226.1 - 0.0062 16.9 0.1 4.9e+02 1.3 0.0 5.6 6 0 0 6 6 6 0 Scorpion short toxin DUF4633 PF15464.6 PSC76226.1 - 0.071 13.3 1.9 5.3e+02 0.8 0.0 5.5 6 0 0 6 6 6 0 Domain of unknown function (DUF4633) Flocculin PF00624.18 PSC76226.1 - 3.4 8.0 17.9 1.7e+02 2.5 0.1 6.1 6 0 0 6 6 6 0 Flocculin repeat DUF72 PF01904.18 PSC76227.1 - 5.7e-36 124.7 0.3 7e-36 124.4 0.3 1.1 1 0 0 1 1 1 1 Protein of unknown function DUF72 Phage_holin_3_1 PF05106.12 PSC76227.1 - 0.014 15.9 0.0 0.025 15.0 0.0 1.4 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) EccE PF11203.8 PSC76227.1 - 0.14 12.5 2.5 1.7 9.0 2.5 2.6 1 1 0 1 1 1 0 Putative type VII ESX secretion system translocon, EccE CPP1-like PF11833.8 PSC76228.1 - 9.4e-41 139.6 0.0 1.1e-40 139.4 0.0 1.1 1 0 0 1 1 1 1 Protein CHAPERONE-LIKE PROTEIN OF POR1-like GATA PF00320.27 PSC76229.1 - 2.7e-12 46.0 9.7 4.7e-12 45.3 9.7 1.4 1 0 0 1 1 1 1 GATA zinc finger KH_8 PF17903.1 PSC76230.1 - 0.00095 19.2 0.0 0.0017 18.4 0.0 1.3 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 PSC76230.1 - 0.016 15.1 0.2 0.033 14.0 0.2 1.5 1 0 0 1 1 1 0 KH domain Ribosomal_L34 PF00468.17 PSC76231.1 - 4.1e-15 55.5 9.3 7.5e-15 54.6 9.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 Exo_endo_phos PF03372.23 PSC76232.1 - 1.1e-17 64.4 5.2 6.9e-13 48.7 0.0 2.6 2 1 0 2 2 2 2 Endonuclease/Exonuclease/phosphatase family zf-CCCH PF00642.24 PSC76232.1 - 2.1e-06 27.5 2.6 4.7e-06 26.4 2.6 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PSC76232.1 - 4.6e-06 26.3 3.5 8.3e-06 25.5 3.5 1.4 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 PSC76232.1 - 1e-05 25.4 4.6 2e-05 24.5 4.6 1.5 1 0 0 1 1 1 1 Zinc finger domain Torus PF16131.5 PSC76232.1 - 0.0013 19.4 0.1 0.0027 18.4 0.1 1.5 1 0 0 1 1 1 1 Torus domain zf-CCCH_2 PF14608.6 PSC76232.1 - 0.45 11.1 2.2 0.99 10.0 2.2 1.6 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger RskA PF10099.9 PSC76232.1 - 6.6 7.0 28.7 2.1 8.6 5.7 3.5 3 0 0 3 3 3 0 Anti-sigma-K factor rskA Oxidored_q6 PF01058.22 PSC76233.1 - 1.2e-21 76.9 0.0 1.4e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit TSGP1 PF07771.11 PSC76234.1 - 1.8 8.7 5.7 4.3 7.5 5.7 1.6 1 0 0 1 1 1 0 Tick salivary peptide group 1 TMF_TATA_bd PF12325.8 PSC76234.1 - 6.9 6.9 11.1 0.21 11.8 3.8 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Cyclin_N PF00134.23 PSC76235.1 - 6.7e-46 155.2 1.2 1.3e-45 154.3 1.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 PSC76235.1 - 1.2e-34 118.9 0.3 2.8e-34 117.8 0.3 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain HEPN_Toprim_N PF18871.1 PSC76235.1 - 0.039 13.9 0.0 0.063 13.2 0.0 1.3 1 0 0 1 1 1 0 HEPN/Toprim N-terminal domain 1 ABC2_membrane PF01061.24 PSC76238.1 - 7.2e-14 51.7 25.3 8.6e-09 35.1 0.8 2.4 1 1 1 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 PSC76238.1 - 3.5e-06 27.6 0.0 5.6e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 PSC76238.1 - 0.18 11.6 0.0 0.27 11.0 0.0 1.2 1 0 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system UNC-93 PF05978.16 PSC76238.1 - 0.21 11.3 8.9 0.53 10.0 8.9 1.7 1 0 0 1 1 1 0 Ion channel regulatory protein UNC-93 NAD_kinase PF01513.21 PSC76239.1 - 1.5e-52 178.7 0.0 3.2e-52 177.5 0.0 1.5 1 1 0 1 1 1 1 ATP-NAD kinase Cupin_5 PF06172.11 PSC76239.1 - 5.9e-41 139.9 0.0 9.1e-41 139.3 0.0 1.3 1 0 0 1 1 1 1 Cupin superfamily (DUF985) Hairy_orange PF07527.13 PSC76239.1 - 0.34 11.2 1.6 9.4 6.5 0.0 3.3 3 1 0 3 3 3 0 Hairy Orange MFS_1 PF07690.16 PSC76240.1 - 3.2e-41 141.4 69.9 2.6e-38 131.9 46.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Fasciclin PF02469.22 PSC76241.1 - 1.5e-21 77.0 0.1 1.8e-21 76.7 0.1 1.1 1 0 0 1 1 1 1 Fasciclin domain ABC_membrane PF00664.23 PSC76242.1 - 2.6e-66 224.1 11.5 1.8e-36 126.3 4.1 2.1 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 PSC76242.1 - 2e-49 167.6 0.0 1.2e-29 103.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 PSC76242.1 - 9.7e-07 28.4 0.0 0.036 13.5 0.0 3.5 2 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PSC76242.1 - 4.6e-06 27.1 1.2 0.024 15.0 0.1 2.8 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 PSC76242.1 - 7e-06 26.1 0.1 0.096 12.8 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 PSC76242.1 - 4.4e-05 23.1 0.2 0.31 10.8 0.0 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 PSC76242.1 - 6.8e-05 22.8 0.5 4.8 6.9 0.0 4.0 3 1 1 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 PSC76242.1 - 0.00076 18.6 0.0 0.17 10.9 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 PSC76242.1 - 0.00081 19.0 1.0 0.16 11.6 0.1 2.9 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 PSC76242.1 - 0.004 16.4 0.7 0.78 9.0 0.2 2.5 2 0 0 2 2 2 1 Zeta toxin RsgA_GTPase PF03193.16 PSC76242.1 - 0.0045 16.9 0.7 0.65 9.9 0.5 2.4 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 PSC76242.1 - 0.024 14.7 1.5 0.052 13.6 0.6 1.9 2 0 0 2 2 2 0 Dynamin family AAA_22 PF13401.6 PSC76242.1 - 0.064 13.5 0.8 9.8 6.5 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.6 PSC76242.1 - 0.13 12.7 0.0 15 6.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.18 PSC76242.1 - 0.21 11.3 0.1 20 4.8 0.0 2.5 3 0 0 3 3 2 0 Viral (Superfamily 1) RNA helicase TrwB_AAD_bind PF10412.9 PSC76242.1 - 0.24 10.2 0.4 9.6 5.0 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF815 PF05673.13 PSC76242.1 - 0.26 10.4 0.5 2.9 7.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_7 PF12775.7 PSC76242.1 - 0.28 10.7 0.1 8.5 5.8 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 PSC76242.1 - 1.2 9.0 2.7 17 5.3 0.2 2.8 3 0 0 3 3 3 0 NACHT domain SPRY PF00622.28 PSC76243.1 - 1.1e-27 96.5 0.1 2.3e-27 95.5 0.1 1.5 2 0 0 2 2 2 1 SPRY domain CLTH PF10607.9 PSC76243.1 - 2.4e-14 53.5 0.0 3.4e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain Phage_integrase PF00589.22 PSC76244.1 - 0.22 11.3 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Phage integrase family Apt1 PF10351.9 PSC76244.1 - 1.5 7.6 7.5 1.9 7.3 7.5 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain SSP160 PF06933.11 PSC76244.1 - 1.9 6.6 21.0 2.6 6.1 21.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Herpes_capsid PF06112.11 PSC76244.1 - 4.4 7.3 22.3 0.22 11.6 16.8 1.6 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein ANAPC4_WD40 PF12894.7 PSC76245.1 - 4.3e-07 30.1 0.0 0.55 10.6 0.0 4.6 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleo_P87 PF07267.11 PSC76245.1 - 1.6 7.5 2.9 2.2 7.0 2.9 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 HAT_KAT11 PF08214.11 PSC76246.1 - 3.3e-21 76.0 0.0 3.3e-21 76.0 0.0 3.3 3 1 0 3 3 3 1 Histone acetylation protein zf-TAZ PF02135.16 PSC76246.1 - 1.9e-19 69.9 43.4 2.5e-12 47.1 17.6 4.9 5 0 0 5 5 5 2 TAZ zinc finger Ion_trans_2 PF07885.16 PSC76246.1 - 7e-11 41.9 1.5 2.3e-10 40.3 1.5 1.9 1 0 0 1 1 1 1 Ion channel ZZ PF00569.17 PSC76246.1 - 1.5e-07 31.1 7.3 1.5e-07 31.1 7.3 2.8 2 0 0 2 2 2 1 Zinc finger, ZZ type cNMP_binding PF00027.29 PSC76246.1 - 2.1e-07 30.9 0.0 4.3e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Cyclic nucleotide-binding domain PHD PF00628.29 PSC76246.1 - 6e-06 26.1 2.7 6e-06 26.1 2.7 3.6 3 0 0 3 3 3 1 PHD-finger DUF902 PF06001.13 PSC76246.1 - 0.24 11.9 2.2 0.61 10.6 2.2 1.6 1 0 0 1 1 1 0 Domain of Unknown Function (DUF902) DDHD PF02862.17 PSC76246.1 - 0.33 11.1 12.4 1.5 8.9 2.9 2.6 2 0 0 2 2 2 0 DDHD domain FAM222A PF15258.6 PSC76246.1 - 7 5.6 58.9 0.8 8.7 21.2 2.8 2 0 0 2 2 2 0 Protein family of FAM222A Methyltransf_24 PF13578.6 PSC76248.1 - 0.025 15.6 0.3 13 6.9 0.1 2.6 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_24 PF13578.6 PSC76249.1 - 0.025 15.6 0.3 13 6.9 0.1 2.6 2 1 1 3 3 3 0 Methyltransferase domain zf-U1 PF06220.12 PSC76250.1 - 1.5e-08 34.3 0.3 2.5e-08 33.6 0.3 1.4 1 0 0 1 1 1 1 U1 zinc finger OCRE PF17780.1 PSC76250.1 - 0.0001 22.2 3.2 0.00021 21.2 3.2 1.5 1 0 0 1 1 1 1 OCRE domain CTU2 PF10288.9 PSC76250.1 - 0.71 10.1 2.5 1.5 9.1 2.5 1.6 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 zn-ribbon_14 PF16503.5 PSC76251.1 - 3.1e-17 61.8 3.5 3.1e-17 61.8 3.5 2.1 2 0 0 2 2 2 1 Zinc-ribbon ATP_bind_3 PF01171.20 PSC76251.1 - 7e-15 55.2 0.0 1.1e-14 54.6 0.0 1.3 1 0 0 1 1 1 1 PP-loop family ThiI PF02568.14 PSC76251.1 - 0.027 14.1 0.0 0.049 13.2 0.0 1.3 1 0 0 1 1 1 0 Thiamine biosynthesis protein (ThiI) tRNA_Me_trans PF03054.16 PSC76251.1 - 0.034 12.9 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase PAPS_reduct PF01507.19 PSC76251.1 - 0.071 13.2 0.0 0.071 13.2 0.0 1.8 2 0 0 2 2 2 0 Phosphoadenosine phosphosulfate reductase family RecR PF02132.15 PSC76251.1 - 0.21 11.2 3.2 0.2 11.3 1.0 1.9 2 0 0 2 2 2 0 RecR protein CTU2 PF10288.9 PSC76251.1 - 5.7 7.2 6.7 78 3.6 0.0 3.6 4 0 0 4 4 4 0 Cytoplasmic tRNA 2-thiolation protein 2 Sulfate_transp PF00916.20 PSC76252.1 - 9e-21 74.0 18.8 1.5e-20 73.3 18.8 1.3 1 0 0 1 1 1 1 Sulfate permease family cNMP_binding PF00027.29 PSC76252.1 - 7.8e-11 41.9 0.0 2.4e-10 40.3 0.0 1.9 1 1 0 1 1 1 1 Cyclic nucleotide-binding domain STAS PF01740.21 PSC76252.1 - 4.5e-07 29.5 0.0 1e-06 28.4 0.0 1.5 1 1 0 1 1 1 1 STAS domain Glyco_hydro_125 PF06824.11 PSC76253.1 - 7.1e-102 341.4 0.0 8.5e-102 341.1 0.0 1.0 1 0 0 1 1 1 1 Metal-independent alpha-mannosidase (GH125) Fasciclin PF02469.22 PSC76254.1 - 1.1e-26 93.6 0.0 2e-15 57.1 0.0 3.4 3 1 0 3 3 3 2 Fasciclin domain Nucleotid_trans PF03407.16 PSC76255.1 - 1.7e-34 119.7 0.0 2.5e-34 119.1 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Nucleotid_trans PF03407.16 PSC76256.1 - 1.6e-34 119.7 0.0 2.4e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase DUF866 PF05907.13 PSC76257.1 - 2.3e-34 118.5 0.0 2.7e-34 118.3 0.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Pex19 PF04614.12 PSC76258.1 - 0.0014 18.5 9.1 0.0018 18.1 9.1 1.1 1 0 0 1 1 1 1 Pex19 protein family TFIIA PF03153.13 PSC76258.1 - 0.0067 16.5 32.7 0.008 16.2 32.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit APG5 PF04106.12 PSC76258.1 - 0.04 13.5 0.4 0.042 13.4 0.4 1.1 1 0 0 1 1 1 0 Autophagy protein Apg5 DDHD PF02862.17 PSC76258.1 - 0.23 11.6 3.9 0.28 11.3 3.9 1.2 1 0 0 1 1 1 0 DDHD domain DUF4449 PF14613.6 PSC76258.1 - 0.29 11.2 15.6 0.44 10.6 15.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) UPF0565 PF10561.9 PSC76258.1 - 0.48 9.6 6.4 0.67 9.1 6.4 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 CHD5 PF04420.14 PSC76258.1 - 0.55 10.1 10.2 1 9.2 10.2 1.4 1 0 0 1 1 1 0 CHD5-like protein Presenilin PF01080.17 PSC76258.1 - 0.77 8.5 8.2 0.87 8.3 8.2 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 PSC76258.1 - 0.89 8.2 12.3 1.1 7.9 12.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAT1 PF09770.9 PSC76258.1 - 1.1 7.4 23.3 1.4 7.1 23.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 PSC76258.1 - 1.7 5.7 10.4 1.9 5.5 10.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Membralin PF09746.9 PSC76258.1 - 1.9 7.5 5.9 2.4 7.1 5.9 1.1 1 0 0 1 1 1 0 Tumour-associated protein CCSAP PF15748.5 PSC76258.1 - 2 8.5 12.1 2.8 8.1 12.1 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF4407 PF14362.6 PSC76258.1 - 3.1 7.1 23.6 4.9 6.4 23.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PIN_8 PF18476.1 PSC76258.1 - 4.4 7.1 10.2 6.2 6.6 10.2 1.2 1 0 0 1 1 1 0 PIN like domain XRN_M PF17846.1 PSC76258.1 - 5.3 5.9 9.0 6.6 5.6 9.0 1.1 1 0 0 1 1 1 0 Xrn1 helical domain MDM10 PF12519.8 PSC76258.1 - 7.6 5.3 10.1 10 4.9 10.1 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 TraG_N PF07916.11 PSC76258.1 - 7.9 5.2 21.9 11 4.7 21.9 1.4 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Spc24 PF08286.11 PSC76258.1 - 9 6.6 8.2 24 5.2 8.2 1.7 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 FliP PF00813.20 PSC76258.1 - 9.5 6.1 6.4 16 5.3 6.4 1.4 1 0 0 1 1 1 0 FliP family ATP_bind_1 PF03029.17 PSC76259.1 - 8.3e-87 291.0 0.1 1.6e-86 290.0 0.1 1.5 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GWT1 PF06423.12 PSC76259.1 - 4e-25 88.7 0.0 2e-24 86.4 0.0 2.2 1 0 0 1 1 1 1 GWT1 CLP1_P PF16575.5 PSC76259.1 - 0.0049 16.7 0.0 0.019 14.7 0.0 2.0 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_29 PF13555.6 PSC76259.1 - 0.064 13.0 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF1655 PF07868.11 PSC76259.1 - 0.067 13.2 0.0 0.16 12.0 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1655) AAA_16 PF13191.6 PSC76259.1 - 0.12 12.7 0.0 0.12 12.7 0.0 4.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 PSC76259.1 - 0.45 10.8 0.0 0.45 10.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.27 PSC76259.1 - 1.5 9.3 0.0 1.5 9.3 0.0 3.5 2 1 0 2 2 2 0 ABC transporter Spore_III_AE PF09546.10 PSC76260.1 - 0.11 11.7 4.1 0.12 11.5 3.4 1.4 1 1 0 1 1 1 0 Stage III sporulation protein AE (spore_III_AE) Methyltr_RsmB-F PF01189.17 PSC76261.1 - 1.2e-36 126.3 0.0 3.2e-36 124.9 0.0 1.7 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 PSC76261.1 - 0.00041 20.5 0.0 0.0007 19.8 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pkinase PF00069.25 PSC76263.1 - 1.2e-73 247.7 0.0 2.8e-40 138.4 0.0 3.3 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC76263.1 - 3.9e-70 236.1 0.0 1.4e-39 136.0 0.0 3.6 3 1 0 3 3 3 3 Protein tyrosine kinase Dynamin_M PF01031.20 PSC76263.1 - 5.1e-30 104.7 0.0 9.7e-30 103.7 0.0 1.4 1 0 0 1 1 1 1 Dynamin central region Dynamin_N PF00350.23 PSC76263.1 - 5.1e-25 88.5 0.3 5.8e-24 85.0 0.3 2.3 1 1 0 1 1 1 1 Dynamin family Kdo PF06293.14 PSC76263.1 - 4.4e-08 32.7 1.9 0.0025 17.2 0.1 2.7 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 PSC76263.1 - 1.4e-05 24.1 0.1 0.0035 16.2 0.0 2.6 3 0 0 3 3 3 2 Fungal protein kinase MMR_HSR1 PF01926.23 PSC76263.1 - 0.0022 18.1 0.0 0.0049 16.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF2489 PF10675.9 PSC76263.1 - 0.0043 17.0 0.3 0.013 15.4 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2489) SIKE PF05769.11 PSC76263.1 - 0.24 11.3 7.2 0.9 9.4 0.4 3.2 3 0 0 3 3 3 0 SIKE family EFF-AFF PF14884.6 PSC76263.1 - 0.51 8.4 3.3 2 6.5 0.1 2.4 2 0 0 2 2 2 0 Type I membrane glycoproteins cell-cell fusogen DUF501 PF04417.12 PSC76263.1 - 5.2 6.9 7.3 4.6 7.0 1.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF501) DUF21 PF01595.20 PSC76264.1 - 3.9e-33 114.6 0.8 1.5e-32 112.7 0.8 2.1 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain MatE PF01554.18 PSC76264.1 - 2.3e-09 37.1 6.4 2.3e-09 37.1 6.4 4.1 4 1 0 4 4 4 2 MatE Polysacc_synt_C PF14667.6 PSC76264.1 - 1e-05 25.7 5.9 1e-05 25.7 5.9 4.4 5 1 0 5 5 5 1 Polysaccharide biosynthesis C-terminal domain CBS PF00571.28 PSC76264.1 - 1.2e-05 25.6 0.7 0.045 14.2 0.1 2.5 2 0 0 2 2 2 2 CBS domain DAP10 PF07213.11 PSC76265.1 - 6.5 6.8 6.6 9 6.3 0.7 3.2 3 0 0 3 3 3 0 DAP10 membrane protein NHL PF01436.21 PSC76266.1 - 5.7e-36 120.8 22.1 2.8e-05 23.9 0.0 10.3 10 0 0 10 10 10 7 NHL repeat DUF5128 PF17170.4 PSC76266.1 - 1.7e-05 24.1 0.0 0.4 9.8 0.0 3.9 3 1 1 4 4 4 2 6-bladed beta-propeller SGL PF08450.12 PSC76266.1 - 0.0034 17.0 6.0 12 5.4 0.0 5.1 3 2 0 4 4 4 1 SMP-30/Gluconolactonase/LRE-like region Phytase-like PF13449.6 PSC76266.1 - 0.0065 16.4 0.1 6.4 6.6 0.0 4.1 3 1 0 3 3 3 1 Esterase-like activity of phytase PQQ_3 PF13570.6 PSC76266.1 - 0.037 14.5 25.3 3.1 8.4 0.0 7.7 8 0 0 8 8 8 0 PQQ-like domain DUF4934 PF16288.5 PSC76266.1 - 0.058 13.3 0.3 40 4.2 0.1 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4934) SdiA-regulated PF06977.11 PSC76266.1 - 0.19 11.0 0.0 15 4.7 0.0 3.3 4 0 0 4 4 4 0 SdiA-regulated DUF553 PF04473.12 PSC76266.1 - 0.26 10.8 1.0 5.5 6.5 0.1 2.9 2 1 0 2 2 2 0 Transglutaminase-like domain SBBP PF06739.11 PSC76266.1 - 8.3 6.5 15.8 9.8 6.3 0.4 5.4 7 0 0 7 7 7 0 Beta-propeller repeat Lon_C PF05362.13 PSC76267.1 - 2.7e-65 219.7 0.0 4.4e-65 219.1 0.0 1.3 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 PSC76267.1 - 1.6e-20 73.9 0.0 4.1e-20 72.6 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) LON_substr_bdg PF02190.16 PSC76267.1 - 3.5e-16 59.7 0.0 6.1e-16 58.9 0.0 1.4 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain AAA_5 PF07728.14 PSC76267.1 - 1.7e-09 37.8 0.0 4.5e-08 33.2 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ChlI PF13541.6 PSC76267.1 - 1.8e-07 31.0 0.0 4.4e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 PSC76267.1 - 0.00011 22.6 1.2 0.0033 17.8 0.1 3.2 2 1 0 2 2 2 1 AAA ATPase domain AAA_PrkA PF08298.11 PSC76267.1 - 0.0004 19.4 0.0 0.00062 18.8 0.0 1.1 1 0 0 1 1 1 1 PrkA AAA domain RuvB_N PF05496.12 PSC76267.1 - 0.0006 19.6 0.0 0.0019 17.9 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PSC76267.1 - 0.0034 17.7 1.8 0.057 13.7 0.0 3.1 3 1 0 3 3 3 1 AAA domain NACHT PF05729.12 PSC76267.1 - 0.0036 17.2 0.1 0.37 10.7 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_2 PF07724.14 PSC76267.1 - 0.0041 17.3 0.0 0.0099 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 PSC76267.1 - 0.012 15.3 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_33 PF13671.6 PSC76267.1 - 0.016 15.3 0.0 0.045 13.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_3 PF07726.11 PSC76267.1 - 0.024 14.5 0.0 0.051 13.4 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 PSC76267.1 - 0.038 14.2 0.7 0.84 9.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 PSC76267.1 - 0.041 14.4 0.0 0.1 13.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 PSC76267.1 - 0.082 12.3 0.0 0.25 10.7 0.0 1.8 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI PHO4 PF01384.20 PSC76268.1 - 1.3e-55 188.8 6.5 1.3e-55 188.8 6.5 1.7 2 1 0 2 2 2 1 Phosphate transporter family Myc_N PF01056.18 PSC76269.1 - 0.014 15.3 2.1 0.019 14.9 2.1 1.1 1 0 0 1 1 1 0 Myc amino-terminal region Roughex PF06020.11 PSC76269.1 - 0.075 12.1 3.2 0.1 11.7 3.2 1.1 1 0 0 1 1 1 0 Drosophila roughex protein RPN2_C PF18004.1 PSC76269.1 - 0.089 12.7 0.8 0.14 12.1 0.8 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain FAM176 PF14851.6 PSC76269.1 - 0.13 11.9 1.9 0.27 10.9 1.9 1.5 1 0 0 1 1 1 0 FAM176 family Paf1 PF03985.13 PSC76269.1 - 2.3 7.2 9.1 3 6.7 9.1 1.1 1 0 0 1 1 1 0 Paf1 Det1 PF09737.9 PSC76270.1 - 6.1e-53 180.4 0.0 6.1e-27 94.7 0.0 4.5 4 0 0 4 4 4 3 De-etiolated protein 1 Det1 Cation_ATPase_C PF00689.21 PSC76270.1 - 8.6e-45 152.7 0.4 2e-44 151.5 0.4 1.7 1 0 0 1 1 1 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 PSC76270.1 - 1.2e-38 132.5 1.2 1.2e-38 132.5 1.2 2.7 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 PSC76270.1 - 1.5e-17 64.6 0.0 7.7e-17 62.3 0.0 2.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 PSC76270.1 - 5.3e-16 58.5 0.0 1.3e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 PSC76270.1 - 4.5e-10 39.1 0.0 1.3e-09 37.6 0.0 1.9 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 PSC76270.1 - 0.0005 19.9 0.6 0.0005 19.9 0.6 3.0 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase PALP PF00291.25 PSC76271.1 - 6.1e-44 150.6 0.1 7.5e-44 150.3 0.1 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme OTU PF02338.19 PSC76272.1 - 1.4e-05 25.6 0.0 2.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease AIG2_2 PF13772.6 PSC76273.1 - 0.22 12.0 0.4 4.9 7.6 0.0 2.7 3 0 0 3 3 3 0 AIG2-like family Ank_2 PF12796.7 PSC76274.1 - 7e-25 87.4 5.6 5.2e-12 46.2 0.2 2.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC76274.1 - 1.1e-17 63.8 2.6 2.8e-11 43.4 0.2 3.5 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC76274.1 - 5.1e-11 42.9 0.0 5.6e-08 33.2 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) STI1 PF17830.1 PSC76274.1 - 6.9e-09 35.5 29.6 3.5e-07 30.0 2.3 5.4 3 1 2 5 5 5 3 STI1 domain Ank_3 PF13606.6 PSC76274.1 - 3.7e-08 33.0 0.0 0.00097 19.4 0.0 3.1 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.30 PSC76274.1 - 2.4e-06 27.7 0.0 0.0098 16.3 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat HAP1_N PF04849.13 PSC76274.1 - 0.0011 18.3 7.0 0.0011 18.3 7.0 3.6 3 0 0 3 3 3 1 HAP1 N-terminal conserved region GAS PF13851.6 PSC76274.1 - 0.0018 17.7 7.7 0.0018 17.7 7.7 4.9 4 1 1 5 5 5 1 Growth-arrest specific micro-tubule binding DUF4936 PF16290.5 PSC76274.1 - 0.14 12.9 0.2 0.14 12.9 0.2 5.7 4 1 2 6 6 6 0 Domain of unknown function (DUF4936) Atg14 PF10186.9 PSC76274.1 - 0.19 10.8 17.9 0.17 11.0 7.5 3.1 2 1 0 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 GerD PF17898.1 PSC76274.1 - 0.21 11.5 25.2 2.4 8.1 10.1 3.5 2 1 1 3 3 3 0 Spore germination GerD central core domain DUF4201 PF13870.6 PSC76274.1 - 8.5 6.1 17.7 1.1 9.0 3.0 4.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4201) Endonuclease_5 PF04493.14 PSC76275.1 - 1.7e-31 109.5 0.0 2.2e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V TPK_catalytic PF04263.16 PSC76276.1 - 4.2e-35 120.4 0.0 5.6e-35 120.0 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 PSC76276.1 - 4.4e-17 61.6 0.0 6.2e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain SDA1 PF05285.12 PSC76277.1 - 1e-53 183.0 46.2 1e-53 183.0 46.2 2.9 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 PSC76277.1 - 1e-17 64.2 0.1 2.4e-17 63.0 0.1 1.7 1 0 0 1 1 1 1 NUC130/3NT domain Proteasome PF00227.26 PSC76278.1 - 2e-47 161.1 0.3 2.4e-47 160.9 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Lipase_3 PF01764.25 PSC76279.1 - 1.3e-13 51.1 0.0 2.2e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) PGAP1 PF07819.13 PSC76279.1 - 0.00071 19.4 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 PGAP1-like protein RNA_pol_I_A49 PF06870.12 PSC76280.1 - 2.1e-42 145.4 0.0 2.7e-42 145.0 0.0 1.0 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor IF2_N PF04760.15 PSC76280.1 - 0.07 13.0 0.0 0.18 11.7 0.0 1.7 1 0 0 1 1 1 0 Translation initiation factor IF-2, N-terminal region Pep_deformylase PF01327.21 PSC76281.1 - 1.1e-47 161.7 0.0 2.2e-47 160.6 0.0 1.5 1 0 0 1 1 1 1 Polypeptide deformylase Cons_hypoth95 PF03602.15 PSC76281.1 - 2.7e-41 141.2 0.0 4.2e-41 140.6 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 DinB_2 PF12867.7 PSC76281.1 - 0.16 12.5 1.0 0.29 11.6 0.1 1.9 2 0 0 2 2 2 0 DinB superfamily MethyltransfD12 PF02086.15 PSC76281.1 - 0.16 11.6 0.0 0.28 10.8 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase EMC3_TMCO1 PF01956.16 PSC76281.1 - 0.4 10.4 0.6 0.68 9.7 0.6 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like IATP PF04568.12 PSC76281.1 - 2.2 8.7 8.1 0.69 10.4 0.5 2.7 2 0 0 2 2 2 0 Mitochondrial ATPase inhibitor, IATP DUF917 PF06032.12 PSC76282.1 - 7.9e-101 337.4 8.8 1.8e-86 290.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF917) Hydant_A_N PF05378.13 PSC76282.1 - 1.4e-13 51.0 0.0 2.4e-06 27.4 0.0 2.3 1 1 1 2 2 2 2 Hydantoinase/oxoprolinase N-terminal region ketoacyl-synt PF00109.26 PSC76284.1 - 1.5e-52 178.7 4.9 1.5e-52 178.7 4.9 1.8 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 PSC76284.1 - 1e-38 132.0 1.3 1.4e-38 131.5 0.4 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 PSC76284.1 - 1.2e-05 24.8 2.0 1.3e-05 24.7 0.5 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain KAsynt_C_assoc PF16197.5 PSC76284.1 - 0.21 12.1 0.0 0.41 11.1 0.0 1.5 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension ACP_syn_III PF08545.10 PSC76284.1 - 2.6 8.0 14.2 7.3 6.5 0.1 4.0 4 0 0 4 4 4 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Nkap_C PF06047.11 PSC76285.1 - 6.3e-46 154.7 3.5 6.3e-46 154.7 3.5 2.1 2 0 0 2 2 2 1 NF-kappa-B-activating protein C-terminal domain EF-hand_7 PF13499.6 PSC76285.1 - 2.7e-06 27.7 0.1 7.8e-06 26.3 0.1 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 PSC76285.1 - 1.9e-05 24.2 0.0 7.4e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 PSC76285.1 - 0.00011 21.5 0.2 0.0007 19.0 0.0 2.5 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 PSC76285.1 - 0.0093 15.8 0.0 0.047 13.5 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_5 PF13202.6 PSC76285.1 - 0.076 12.5 0.1 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 EF hand DUF2624 PF11116.8 PSC76285.1 - 0.19 12.6 0.4 0.9 10.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) TT_ORF2 PF02957.15 PSC76285.1 - 3.7 8.5 8.2 1.4 9.9 3.3 2.9 1 1 1 2 2 2 0 TT viral ORF2 GATA PF00320.27 PSC76286.1 - 1.9 8.1 6.9 5.3 6.7 6.9 1.8 1 0 0 1 1 1 0 GATA zinc finger Asp-B-Hydro_N PF05279.11 PSC76286.1 - 8 6.5 15.5 12 5.8 15.5 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region YbaB_DNA_bd PF02575.16 PSC76287.1 - 2.4e-19 69.4 4.3 3e-19 69.0 4.3 1.1 1 0 0 1 1 1 1 YbaB/EbfC DNA-binding family Aa_trans PF01490.18 PSC76288.1 - 3.7e-30 105.0 0.4 4.6e-30 104.7 0.4 1.1 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein Arm PF00514.23 PSC76289.1 - 6.7e-08 32.3 33.9 1.9e-06 27.7 0.0 8.6 10 0 0 10 10 10 5 Armadillo/beta-catenin-like repeat Chloroa_b-bind PF00504.21 PSC76290.1 - 8.1e-18 65.5 12.4 1.5e-06 28.9 2.2 4.6 2 2 1 3 3 3 3 Chlorophyll A-B binding protein zf-MYND PF01753.18 PSC76290.1 - 5e-08 32.9 7.4 7.9e-08 32.3 7.4 1.3 1 0 0 1 1 1 1 MYND finger Yip1 PF04893.17 PSC76290.1 - 0.0015 18.3 5.6 0.0015 18.3 5.6 3.2 3 0 0 3 3 3 1 Yip1 domain zf-Mss51 PF13824.6 PSC76290.1 - 0.037 14.1 3.1 0.07 13.2 3.1 1.4 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF2301 PF10063.9 PSC76290.1 - 0.071 13.5 1.1 4.1 7.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) Arr-ms PF12120.8 PSC76290.1 - 0.34 11.1 0.9 43 4.4 0.0 2.8 3 0 0 3 3 3 0 Rifampin ADP-ribosyl transferase Chloroa_b-bind PF00504.21 PSC76291.1 - 8.5e-18 65.4 12.4 1.5e-06 28.9 2.2 4.5 2 2 1 3 3 3 3 Chlorophyll A-B binding protein zf-MYND PF01753.18 PSC76291.1 - 3.6e-05 23.8 3.2 0.0001 22.3 3.2 1.7 1 1 0 1 1 1 1 MYND finger Yip1 PF04893.17 PSC76291.1 - 0.0015 18.3 5.6 0.0015 18.3 5.6 3.2 3 0 0 3 3 3 1 Yip1 domain DUF2301 PF10063.9 PSC76291.1 - 0.073 13.5 1.1 4.2 7.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized integral membrane protein (DUF2301) Arr-ms PF12120.8 PSC76291.1 - 0.35 11.1 0.9 43 4.4 0.0 2.8 3 0 0 3 3 3 0 Rifampin ADP-ribosyl transferase TspO_MBR PF03073.15 PSC76292.1 - 1.5e-51 174.0 11.2 1.7e-51 173.8 11.2 1.0 1 0 0 1 1 1 1 TspO/MBR family 5TM-5TMR_LYT PF07694.12 PSC76292.1 - 0.0046 16.5 2.7 0.0046 16.5 2.7 1.7 2 0 0 2 2 2 1 5TMR of 5TMR-LYT AAA PF00004.29 PSC76293.1 - 2.7e-29 102.3 0.0 4.1e-29 101.7 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PSC76293.1 - 9.9e-13 47.7 1.1 3.4e-12 46.0 0.2 2.4 2 1 0 2 2 2 1 AAA+ lid domain Vps4_C PF09336.10 PSC76293.1 - 1.3e-05 25.1 0.0 6.6e-05 22.8 0.0 2.1 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 PSC76293.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 PSC76293.1 - 0.13 12.5 0.0 0.36 11.1 0.0 1.7 2 0 0 2 2 2 0 AAA domain Mersacidin PF16934.5 PSC76294.1 - 8 6.3 8.7 3.5 7.5 5.3 2.2 2 0 0 2 2 2 0 Two-component Enterococcus faecalis cytolysin (EFC) Mersacidin PF16934.5 PSC76295.1 - 8 6.3 8.7 3.5 7.5 5.3 2.2 2 0 0 2 2 2 0 Two-component Enterococcus faecalis cytolysin (EFC) KDZ PF18758.1 PSC76296.1 - 2.2e-28 99.4 0.0 2.8e-28 99.1 0.0 1.0 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase Aminotran_5 PF00266.19 PSC76297.1 - 1.3e-16 60.5 0.0 2.2e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 PSC76297.1 - 0.0011 17.6 0.0 0.0038 15.8 0.0 1.7 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Lactamase_B_3 PF13483.6 PSC76298.1 - 2.4e-19 69.8 0.0 3.4e-19 69.3 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_2 PF12706.7 PSC76298.1 - 0.0016 18.0 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain HoxA13_N PF12284.8 PSC76298.1 - 0.04 14.5 0.8 0.11 13.1 0.8 1.7 1 0 0 1 1 1 0 Hox protein A13 N terminal DNA_processg_A PF02481.15 PSC76298.1 - 0.085 12.1 0.2 0.16 11.2 0.2 1.4 1 0 0 1 1 1 0 DNA recombination-mediator protein A Peroxin-13_N PF04088.13 PSC76299.1 - 0.032 14.5 0.1 0.046 14.0 0.1 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Peroxin-13_N PF04088.13 PSC76300.1 - 0.032 14.5 0.1 0.046 14.0 0.1 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Peroxin-13_N PF04088.13 PSC76301.1 - 0.033 14.5 0.1 0.047 14.0 0.1 1.2 1 0 0 1 1 1 0 Peroxin 13, N-terminal region RFC1 PF08519.12 PSC76302.1 - 2.1e-45 154.7 0.0 3.8e-45 153.9 0.0 1.4 1 0 0 1 1 1 1 Replication factor RFC1 C terminal domain BRCT PF00533.26 PSC76302.1 - 1.3e-15 57.5 0.0 3.9e-15 56.0 0.0 1.9 2 0 0 2 2 1 1 BRCA1 C Terminus (BRCT) domain AAA PF00004.29 PSC76302.1 - 3.8e-11 43.5 0.0 9e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 PSC76302.1 - 2.1e-06 27.8 0.5 5.5e-05 23.2 0.5 2.4 1 1 0 1 1 1 1 Rad17 P-loop domain RuvB_N PF05496.12 PSC76302.1 - 0.00016 21.5 0.0 0.00035 20.4 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain Zeta_toxin PF06414.12 PSC76302.1 - 0.0012 18.1 0.0 0.0023 17.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_22 PF13401.6 PSC76302.1 - 0.0078 16.5 0.0 0.02 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 PSC76302.1 - 0.0086 16.1 0.0 0.02 14.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PSC76302.1 - 0.014 15.8 1.7 0.043 14.2 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain TIP49 PF06068.13 PSC76302.1 - 0.016 14.4 0.1 0.027 13.7 0.1 1.2 1 0 0 1 1 1 0 TIP49 P-loop domain TsaE PF02367.17 PSC76302.1 - 0.021 14.8 0.0 0.04 13.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PTCB-BRCT PF12738.7 PSC76302.1 - 0.024 14.6 0.0 0.074 13.0 0.0 1.8 1 0 0 1 1 1 0 twin BRCT domain Sigma54_activ_2 PF14532.6 PSC76302.1 - 0.026 14.6 0.0 0.14 12.3 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_33 PF13671.6 PSC76302.1 - 0.032 14.4 1.3 0.11 12.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 PSC76302.1 - 0.034 14.7 0.0 0.59 10.6 0.0 2.6 2 0 0 2 2 2 0 ABC transporter NTPase_1 PF03266.15 PSC76302.1 - 0.041 13.8 0.2 0.47 10.4 0.1 2.3 1 1 1 2 2 2 0 NTPase RNA_helicase PF00910.22 PSC76302.1 - 0.056 13.8 0.0 0.16 12.4 0.0 1.8 1 1 0 1 1 1 0 RNA helicase AAA_18 PF13238.6 PSC76302.1 - 0.098 13.2 0.1 0.24 12.0 0.1 1.7 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 PSC76302.1 - 0.12 11.9 0.0 0.52 9.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region NACHT PF05729.12 PSC76302.1 - 0.15 12.0 0.1 0.45 10.4 0.1 1.8 1 1 0 1 1 1 0 NACHT domain AAA_5 PF07728.14 PSC76302.1 - 0.16 11.9 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) DNA_pol3_delta PF06144.13 PSC76302.1 - 0.17 11.7 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 DNA polymerase III, delta subunit SAGA-Tad1 PF12767.7 PSC76302.1 - 3.7 7.2 5.8 0.47 10.1 0.1 2.3 2 0 0 2 2 2 0 Transcriptional regulator of RNA polII, SAGA, subunit DEAD PF00270.29 PSC76303.1 - 1.2e-44 152.2 0.0 1.9e-44 151.6 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC76303.1 - 3.2e-29 101.5 0.0 4.4e-28 97.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain GUCT PF08152.12 PSC76303.1 - 3.2e-24 85.1 0.0 6.5e-24 84.1 0.0 1.6 1 0 0 1 1 1 1 GUCT (NUC152) domain ResIII PF04851.15 PSC76303.1 - 0.0018 18.3 0.0 0.005 16.9 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 PSC76303.1 - 0.085 12.2 0.0 0.085 12.2 0.0 2.4 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit SNF2_N PF00176.23 PSC76303.1 - 0.088 11.5 0.0 0.14 10.8 0.0 1.2 1 0 0 1 1 1 0 SNF2 family N-terminal domain CPSF100_C PF13299.6 PSC76303.1 - 0.95 9.6 6.2 1.8 8.7 6.2 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Trp_halogenase PF04820.14 PSC76304.1 - 0.0028 16.6 0.0 0.017 14.0 0.0 1.9 2 0 0 2 2 2 1 Tryptophan halogenase DUF3699 PF12480.8 PSC76304.1 - 0.19 11.9 0.0 0.34 11.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3699) TPR_16 PF13432.6 PSC76305.1 - 7e-05 23.4 0.9 7e-05 23.4 0.9 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 PSC76305.1 - 0.006 16.9 1.7 0.011 16.1 0.1 2.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 PSC76305.1 - 0.42 11.2 4.1 1.9 9.0 0.1 2.6 2 1 1 3 3 3 0 Tetratricopeptide repeat HMG_CoA_synt_N PF01154.17 PSC76306.1 - 2.1e-75 252.4 0.0 3e-75 251.9 0.0 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 PSC76306.1 - 1.4e-73 247.9 0.0 2.4e-73 247.2 0.0 1.4 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal ACP_syn_III_C PF08541.10 PSC76306.1 - 0.012 15.8 0.1 0.032 14.4 0.0 1.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal TPR_20 PF14561.6 PSC76306.1 - 0.023 15.0 0.0 2.3 8.6 0.1 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat DUF4781 PF16013.5 PSC76307.1 - 0.17 10.6 0.0 0.37 9.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) TSNAXIP1_N PF15739.5 PSC76308.1 - 2.4 8.6 13.6 2.4 8.6 1.4 3.6 3 0 0 3 3 3 0 Translin-associated factor X-interacting N-terminus FlaC_arch PF05377.11 PSC76308.1 - 6 7.3 11.1 49 4.4 0.1 4.2 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) DUF1664 PF07889.12 PSC76308.1 - 9.6 6.3 14.0 11 6.1 0.6 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1664) Aminotran_1_2 PF00155.21 PSC76309.1 - 3.2e-57 194.4 0.0 4.8e-57 193.8 0.0 1.2 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 PSC76309.1 - 3.8e-07 29.8 0.0 6e-07 29.1 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.19 PSC76309.1 - 3.8e-07 29.4 0.0 5.8e-07 28.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 PSC76309.1 - 4.7e-06 25.4 0.0 7.1e-06 24.8 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 PSC76309.1 - 0.027 13.8 0.0 0.086 12.1 0.0 1.8 2 0 0 2 2 2 0 Beta-eliminating lyase Aminotran_1_2 PF00155.21 PSC76310.1 - 8.5e-62 209.4 0.0 1e-61 209.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 PSC76310.1 - 3.5e-07 29.5 0.0 5.5e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 PSC76310.1 - 3.5e-07 29.9 0.0 5.7e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 PSC76310.1 - 4.4e-06 25.5 0.0 6.8e-06 24.9 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 PSC76310.1 - 0.025 13.8 0.0 0.082 12.2 0.0 1.8 2 0 0 2 2 2 0 Beta-eliminating lyase WD40 PF00400.32 PSC76313.1 - 2.7e-40 135.6 16.8 3.9e-05 24.3 0.0 10.6 10 0 0 10 10 10 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC76313.1 - 3.2e-24 85.0 0.0 8e-05 22.9 0.0 8.1 3 2 5 9 9 9 6 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 PSC76313.1 - 1e-20 74.0 0.0 1.7e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Ge1_WD40 PF16529.5 PSC76313.1 - 6.5e-06 25.3 0.2 0.86 8.5 0.0 4.7 3 2 2 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 PSC76313.1 - 7.3e-05 22.6 4.3 9.5 6.3 0.0 6.5 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 PSC76313.1 - 0.00078 18.9 0.0 0.07 12.5 0.0 2.8 3 0 0 3 3 3 1 WD40-like domain Nup160 PF11715.8 PSC76313.1 - 0.056 12.1 0.1 1.9 7.1 0.0 2.8 3 1 0 3 3 3 0 Nucleoporin Nup120/160 SAP30_Sin3_bdg PF13867.6 PSC76314.1 - 1.7e-16 60.3 0.0 2.6e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Sortilin-Vps10 PF15902.5 PSC76314.1 - 8.6e-06 24.8 1.6 0.46 9.2 0.0 3.3 2 1 0 3 3 3 3 Sortilin, neurotensin receptor 3, NAGPA PF09992.9 PSC76314.1 - 0.0015 18.8 0.8 0.0099 16.1 0.1 2.5 3 0 0 3 3 3 1 Phosphodiester glycosidase SAP30_Sin3_bdg PF13867.6 PSC76315.1 - 1.7e-16 60.3 0.0 2.6e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 Sortilin-Vps10 PF15902.5 PSC76315.1 - 9.7e-06 24.6 1.8 0.46 9.2 0.0 3.3 2 1 0 3 3 3 3 Sortilin, neurotensin receptor 3, NAGPA PF09992.9 PSC76315.1 - 0.0015 18.7 0.9 0.0099 16.1 0.1 2.5 3 0 0 3 3 3 1 Phosphodiester glycosidase Thioredoxin PF00085.20 PSC76316.1 - 1.9e-11 43.8 0.0 2.9e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin UCR_6-4kD PF08997.10 PSC76316.1 - 0.045 13.7 0.3 0.11 12.5 0.3 1.6 1 0 0 1 1 1 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein DUF3464 PF11947.8 PSC76318.1 - 2.2e-43 147.6 0.2 3.3e-43 147.0 0.2 1.4 1 1 0 1 1 1 1 Photosynthesis affected mutant 68 Glucosamine_iso PF01182.20 PSC76319.1 - 4.6e-63 213.1 0.3 6e-63 212.7 0.3 1.2 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase SNF2_N PF00176.23 PSC76320.1 - 8.8e-64 215.4 0.0 1.3e-63 214.8 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 PSC76320.1 - 1.6e-21 76.7 0.0 4.7e-21 75.2 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC76320.1 - 1.7e-06 28.1 0.0 4.7e-06 26.7 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit HDA2-3 PF11496.8 PSC76320.1 - 4.7e-06 26.0 0.0 1.1e-05 24.8 0.0 1.5 1 1 0 1 1 1 1 Class II histone deacetylase complex subunits 2 and 3 ERCC3_RAD25_C PF16203.5 PSC76320.1 - 0.0025 17.1 0.0 0.0054 16.0 0.0 1.5 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Glyco_trans_1_2 PF13524.6 PSC76320.1 - 0.0077 16.6 0.0 1 9.8 0.0 3.6 2 1 1 3 3 3 1 Glycosyl transferases group 1 DEAD PF00270.29 PSC76320.1 - 0.028 14.2 0.0 0.054 13.3 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase SAICAR_synt PF01259.18 PSC76321.1 - 2.8e-73 246.6 0.0 3.5e-73 246.3 0.0 1.1 1 0 0 1 1 1 1 SAICAR synthetase GBP PF02263.19 PSC76322.1 - 1.5e-68 230.9 0.0 2.2e-68 230.3 0.0 1.3 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain GBP_C PF02841.14 PSC76322.1 - 2.3e-23 83.1 13.0 2.3e-23 83.1 13.0 2.7 1 1 1 2 2 2 1 Guanylate-binding protein, C-terminal domain FlaC_arch PF05377.11 PSC76322.1 - 0.25 11.7 1.0 56 4.2 0.1 3.6 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Mei5 PF10376.9 PSC76322.1 - 0.55 10.1 5.8 9.8 6.0 1.4 2.6 1 1 1 2 2 2 0 Double-strand recombination repair protein CENP-F_leu_zip PF10473.9 PSC76322.1 - 0.62 10.1 29.9 1.6 8.7 11.7 3.1 1 1 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pyrophosphatase PF00719.19 PSC76323.1 - 4.6e-47 159.8 0.6 5.9e-47 159.4 0.6 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase Pro_isomerase PF00160.21 PSC76324.1 - 4.4e-49 166.8 0.0 5.8e-49 166.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Peptidase_S8 PF00082.22 PSC76325.1 - 1.4e-21 77.1 9.0 3.6e-18 65.9 7.3 2.8 1 1 2 3 3 3 2 Subtilase family F5_F8_type_C PF00754.25 PSC76325.1 - 1.6e-05 25.0 0.1 4.9e-05 23.4 0.1 1.9 1 0 0 1 1 1 1 F5/8 type C domain LptF_LptG PF03739.14 PSC76325.1 - 0.12 11.2 0.6 0.18 10.6 0.6 1.2 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG CAP_N PF01213.19 PSC76325.1 - 1.4 8.4 4.8 2.6 7.4 0.8 2.2 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal N-glycanase_C PF09113.10 PSC76326.1 - 2.1e-22 79.3 0.0 3.7e-22 78.6 0.0 1.4 1 0 0 1 1 1 1 Peptide-N-glycosidase F, C terminal p450 PF00067.22 PSC76326.1 - 4.5e-16 58.6 0.0 3.1e-10 39.4 0.0 2.9 3 0 0 3 3 3 2 Cytochrome P450 N-glycanase_N PF09112.10 PSC76326.1 - 9.4e-07 28.8 0.0 0.0099 15.7 0.0 2.2 2 0 0 2 2 2 2 Peptide-N-glycosidase F, N terminal PA PF02225.22 PSC76326.1 - 0.98 9.5 5.7 1.5 8.9 0.1 2.7 2 0 0 2 2 2 0 PA domain LOR PF04525.12 PSC76327.1 - 0.00014 21.6 0.0 0.00039 20.1 0.0 1.7 2 0 0 2 2 2 1 LURP-one-related DUF1440 PF07274.12 PSC76327.1 - 0.082 13.2 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) LOR PF04525.12 PSC76328.1 - 0.00014 21.6 0.0 0.00039 20.1 0.0 1.7 2 0 0 2 2 2 1 LURP-one-related DUF1440 PF07274.12 PSC76328.1 - 0.082 13.2 0.0 0.13 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1440) SBP PF03110.14 PSC76329.1 - 4.3e-16 59.0 5.3 4.3e-16 59.0 5.3 1.7 2 0 0 2 2 2 1 SBP domain DEAD PF00270.29 PSC76330.1 - 2.7e-33 115.2 0.0 3.9e-33 114.7 0.0 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC76330.1 - 5.1e-26 91.2 0.0 1.2e-25 90.0 0.0 1.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC76330.1 - 0.035 14.1 0.0 0.09 12.8 0.0 1.7 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit UTP25 PF06862.12 PSC76330.1 - 0.055 12.2 0.0 0.12 11.1 0.0 1.5 1 0 0 1 1 1 0 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DUF4213 PF13938.6 PSC76330.1 - 0.07 13.4 0.5 0.21 11.8 0.0 2.1 2 0 0 2 2 2 0 Putative heavy-metal chelation AAA_22 PF13401.6 PSC76330.1 - 0.12 12.7 0.1 0.65 10.3 0.1 2.1 1 1 0 1 1 1 0 AAA domain LRR_4 PF12799.7 PSC76331.1 - 5.3e-14 52.1 0.0 0.00012 22.4 0.0 5.2 4 1 0 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC76331.1 - 8.1e-10 38.3 4.6 0.00087 19.0 0.2 5.8 3 2 4 7 7 7 4 Leucine rich repeat F-box-like PF12937.7 PSC76331.1 - 9.2e-09 35.1 0.7 9.2e-09 35.1 0.7 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PSC76331.1 - 4.2e-07 29.7 1.0 2.1e-06 27.5 1.0 2.2 1 0 0 1 1 1 1 F-box domain LRR_9 PF14580.6 PSC76331.1 - 0.00028 20.4 0.0 0.0046 16.5 0.0 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_1 PF00560.33 PSC76331.1 - 0.00063 19.9 1.7 21 6.1 0.0 5.8 6 0 0 6 6 6 1 Leucine Rich Repeat F-box_5 PF18511.1 PSC76331.1 - 0.081 12.5 0.6 0.15 11.6 0.6 1.4 1 0 0 1 1 1 0 F-box DUF4571 PF15137.6 PSC76331.1 - 0.094 12.3 0.1 0.44 10.2 0.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4571) HECT PF00632.25 PSC76332.1 - 1.9e-45 155.7 0.0 8.6e-45 153.5 0.0 1.9 1 1 0 1 1 1 1 HECT-domain (ubiquitin-transferase) ubiquitin PF00240.23 PSC76332.1 - 0.039 13.7 0.0 8.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Ubiquitin family RBD PF02196.15 PSC76332.1 - 0.12 12.4 0.0 2.3 8.3 0.0 2.6 2 0 0 2 2 2 0 Raf-like Ras-binding domain 2OG-FeII_Oxy_2 PF13532.6 PSC76333.1 - 2.1e-12 47.7 0.0 1.1e-11 45.3 0.0 2.2 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 PSC76333.1 - 0.0098 16.4 0.0 0.018 15.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily LPP20 PF02169.16 PSC76333.1 - 0.044 14.1 1.4 0.12 12.7 1.4 1.7 1 0 0 1 1 1 0 LPP20 lipoprotein DUF2722 PF10846.8 PSC76333.1 - 3.7 6.4 17.0 2 7.3 3.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Myb_DNA-binding PF00249.31 PSC76334.1 - 1.3e-10 41.3 0.2 1.6e-05 25.0 0.0 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC76334.1 - 2.3e-07 31.0 0.1 4.8e-05 23.5 0.0 3.3 3 0 0 3 3 3 1 Myb-like DNA-binding domain GTP_EFTU PF00009.27 PSC76335.1 - 3.5e-42 144.1 0.0 4.7e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 PSC76335.1 - 1.4e-29 102.7 0.3 4e-29 101.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 PSC76335.1 - 2.3e-08 34.3 0.9 6e-08 33.0 0.2 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 PSC76335.1 - 0.026 14.6 0.0 0.15 12.2 0.0 2.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase Peptidase_M35 PF02102.15 PSC76335.1 - 0.029 13.3 0.0 0.043 12.7 0.0 1.1 1 0 0 1 1 1 0 Deuterolysin metalloprotease (M35) family G-alpha PF00503.20 PSC76335.1 - 0.054 12.7 0.0 0.079 12.1 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit UQ_con PF00179.26 PSC76337.1 - 2.7e-37 127.5 0.0 3.3e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ribosomal_L7Ae PF01248.26 PSC76338.1 - 1e-26 92.4 0.1 1.2e-26 92.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 PSC76338.1 - 0.00012 21.9 0.0 0.00015 21.5 0.0 1.2 1 0 0 1 1 1 1 PELOTA RNA binding domain YadA_stalk PF05662.14 PSC76338.1 - 0.062 13.7 3.0 1.5 9.3 0.1 2.5 2 1 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin MS_channel PF00924.18 PSC76339.1 - 3e-21 75.9 0.0 5e-21 75.2 0.0 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel BLOC1_2 PF10046.9 PSC76340.1 - 6.5e-12 45.6 0.0 9.9e-12 45.0 0.0 1.3 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 GATase PF00117.28 PSC76340.1 - 2.1e-05 24.4 0.0 0.00022 21.0 0.0 2.1 1 1 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 PSC76340.1 - 0.00054 19.8 0.3 1.5 8.5 0.1 2.8 3 0 0 3 3 3 2 Peptidase C26 SlyX PF04102.12 PSC76340.1 - 0.75 10.5 3.2 0.91 10.2 0.1 2.5 3 0 0 3 3 3 0 SlyX Zw10 PF06248.13 PSC76341.1 - 5.3e-20 71.5 0.0 1.1e-14 53.9 0.0 2.1 2 0 0 2 2 2 2 Centromere/kinetochore Zw10 CUE PF02845.16 PSC76342.1 - 0.12 12.1 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 CUE domain DUF1682 PF07946.14 PSC76342.1 - 0.96 8.6 8.0 1.1 8.4 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) FMO-like PF00743.19 PSC76343.1 - 1.5e-29 102.9 0.0 1.1e-21 76.8 0.0 2.5 2 1 0 2 2 2 2 Flavin-binding monooxygenase-like Pyr_redox_2 PF07992.14 PSC76343.1 - 1.2e-16 60.9 0.0 4.2e-12 45.9 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PSC76343.1 - 1.1e-15 57.8 0.0 3e-12 46.4 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 PSC76343.1 - 1.6e-10 40.7 0.1 6.5e-08 32.1 0.0 2.5 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Amino_oxidase PF01593.24 PSC76343.1 - 2.9e-10 40.1 0.0 6e-06 25.8 0.1 3.3 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PSC76343.1 - 5.6e-10 39.3 0.2 1.5e-09 37.9 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 PSC76343.1 - 1e-09 38.5 5.9 0.00046 19.9 0.4 3.2 1 1 1 3 3 3 3 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 PSC76343.1 - 4.6e-09 36.4 0.8 0.02 14.9 0.1 3.4 3 0 0 3 3 3 2 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 PSC76343.1 - 4.7e-09 35.8 0.0 9.2e-06 25.0 0.8 2.6 2 0 0 2 2 2 2 FAD binding domain Pyr_redox PF00070.27 PSC76343.1 - 1.5e-07 31.9 0.8 0.0083 16.7 0.1 2.6 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PSC76343.1 - 3.7e-05 22.6 0.5 0.00079 18.2 0.2 2.3 2 0 0 2 2 2 1 HI0933-like protein AlaDh_PNT_C PF01262.21 PSC76343.1 - 8.4e-05 22.0 0.3 0.00025 20.4 0.0 1.8 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 PSC76343.1 - 0.00023 20.3 1.6 0.22 10.5 0.0 3.1 3 0 0 3 3 3 2 Lycopene cyclase protein FAD_oxidored PF12831.7 PSC76343.1 - 0.0033 16.8 0.1 0.0033 16.8 0.1 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 PSC76343.1 - 0.0042 16.4 1.5 0.0086 15.3 0.0 2.1 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.22 PSC76343.1 - 0.0048 16.0 5.1 0.034 13.2 0.6 2.9 3 0 0 3 3 3 1 Glucose inhibited division protein A NAD_binding_7 PF13241.6 PSC76343.1 - 0.029 14.8 1.5 10 6.6 0.0 3.3 2 2 0 2 2 2 0 Putative NAD(P)-binding FAD_binding_3 PF01494.19 PSC76343.1 - 0.036 13.3 0.2 0.12 11.6 0.2 1.8 2 0 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 PSC76343.1 - 0.055 13.4 0.2 0.055 13.4 0.2 1.6 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.6 PSC76343.1 - 0.064 13.8 0.1 3.9 8.0 0.0 2.6 2 0 0 2 2 2 0 XdhC Rossmann domain 2-Hacid_dh_C PF02826.19 PSC76343.1 - 0.065 12.6 0.6 3.6 6.9 0.1 3.0 3 1 1 4 4 4 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 PSC76343.1 - 0.095 12.8 0.2 12 5.9 0.0 2.8 3 0 0 3 3 3 0 Shikimate / quinate 5-dehydrogenase IlvN PF07991.12 PSC76343.1 - 0.11 12.0 0.7 0.64 9.6 0.1 2.1 2 0 0 2 2 2 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain Profilin PF00235.19 PSC76344.1 - 5.5e-06 26.7 0.0 6.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Profilin Profilin PF00235.19 PSC76345.1 - 5.5e-06 26.7 0.0 6.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Profilin Ocnus PF05005.15 PSC76346.1 - 7.8e-24 83.9 0.0 1.2e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Janus/Ocnus family (Ocnus) NUDIX PF00293.28 PSC76346.1 - 4.2e-09 36.5 0.1 1.9e-07 31.1 0.0 3.0 3 0 0 3 3 3 1 NUDIX domain NUDIX-like PF09296.11 PSC76346.1 - 3.8e-08 33.9 0.1 3.8e-08 33.9 0.1 3.0 3 0 0 3 3 3 1 NADH pyrophosphatase-like rudimentary NUDIX domain zf-NADH-PPase PF09297.11 PSC76346.1 - 0.0018 17.9 0.5 0.0039 16.8 0.5 1.6 1 0 0 1 1 1 1 NADH pyrophosphatase zinc ribbon domain Mito_carr PF00153.27 PSC76347.1 - 6.8e-52 173.4 0.9 3.9e-20 71.6 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 PSC76347.1 - 4.8e-20 71.8 0.0 4.9e-10 39.7 0.0 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 PSC76347.1 - 1.4e-19 68.1 0.1 4.7e-05 22.6 0.1 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 PSC76347.1 - 1e-18 65.6 0.2 0.0011 18.7 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 PSC76347.1 - 1.3e-11 43.5 2.2 0.0019 17.6 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 PSC76347.1 - 4.3e-09 36.1 0.1 5e-05 23.1 0.0 3.4 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 PSC76347.1 - 0.028 14.7 0.0 0.79 10.1 0.0 2.3 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region S1 PF00575.23 PSC76348.1 - 1.1e-60 201.9 0.3 2.2e-10 40.7 0.4 13.3 14 0 0 14 14 14 11 S1 RNA binding domain BRF1 PF07741.13 PSC76348.1 - 8.8 6.7 9.3 11 6.4 0.0 3.1 3 0 0 3 3 3 0 Brf1-like TBP-binding domain Pkinase PF00069.25 PSC76349.1 - 1.8e-21 76.7 0.0 2.8e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC76349.1 - 9.1e-09 35.0 0.0 1.5e-08 34.3 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase eIF-1a PF01176.19 PSC76350.1 - 1.3e-08 34.5 0.0 1.8e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Flavin_Reduct PF01613.18 PSC76351.1 - 4.6e-20 72.2 0.0 1.1e-19 71.0 0.0 1.6 1 0 0 1 1 1 1 Flavin reductase like domain Flavodoxin_1 PF00258.25 PSC76351.1 - 1e-09 38.7 0.0 4e-09 36.8 0.0 2.0 2 0 0 2 2 2 1 Flavodoxin Flavodoxin_5 PF12724.7 PSC76351.1 - 0.0011 19.2 0.0 0.0032 17.7 0.0 1.8 2 0 0 2 2 2 1 Flavodoxin domain MdcG PF10620.9 PSC76351.1 - 0.02 14.7 0.7 0.53 10.0 0.0 3.0 3 0 0 3 3 3 0 Phosphoribosyl-dephospho-CoA transferase MdcG Flavodoxin_3 PF12641.7 PSC76351.1 - 0.16 11.7 0.0 0.53 10.0 0.0 1.9 2 0 0 2 2 2 0 Flavodoxin domain Mito_carr PF00153.27 PSC76352.1 - 6.5e-40 135.0 1.2 3.6e-23 81.3 0.1 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein Mito_carr PF00153.27 PSC76353.1 - 6.7e-40 134.9 1.2 3.5e-23 81.3 0.1 2.2 2 0 0 2 2 2 2 Mitochondrial carrier protein DUF4457 PF14652.6 PSC76354.1 - 8.4e-88 294.7 0.0 7.5e-41 140.4 0.0 3.2 3 0 0 3 3 3 3 Domain of unknown function (DUF4457) DAO PF01266.24 PSC76354.1 - 5.3e-39 134.8 1.9 1.3e-38 133.6 1.9 1.6 1 0 0 1 1 1 1 FAD dependent oxidoreductase UCH PF00443.29 PSC76355.1 - 1.2e-48 165.9 0.0 2.2e-48 165.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PSC76355.1 - 2e-18 67.1 0.0 8.3e-16 58.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase eIF3_subunit PF08597.10 PSC76355.1 - 0.001 19.1 6.4 0.001 19.1 6.4 2.9 3 1 0 3 3 3 1 Translation initiation factor eIF3 subunit UCH PF00443.29 PSC76356.1 - 1.2e-48 165.9 0.0 2.2e-48 165.0 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PSC76356.1 - 2e-18 67.1 0.0 8.2e-16 58.5 0.0 2.2 2 0 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase eIF3_subunit PF08597.10 PSC76356.1 - 0.001 19.1 6.4 0.001 19.1 6.4 2.9 3 1 0 3 3 3 1 Translation initiation factor eIF3 subunit Lum_binding PF00677.17 PSC76357.1 - 3.3e-45 152.0 1.3 1.5e-21 76.1 0.1 2.2 2 0 0 2 2 2 2 Lumazine binding domain DUF2291 PF10054.9 PSC76357.1 - 0.0067 16.2 0.0 0.14 11.8 0.0 2.2 2 0 0 2 2 2 1 Predicted periplasmic lipoprotein (DUF2291) Clat_adaptor_s PF01217.20 PSC76358.1 - 6.5e-06 26.1 0.0 8.4e-06 25.8 0.0 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CPBP PF02517.16 PSC76359.1 - 1.5e-12 47.7 5.4 3.2e-12 46.7 5.4 1.5 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease Polysacc_deac_1 PF01522.21 PSC76360.1 - 1.5e-09 37.8 0.0 2.6e-08 33.8 0.0 2.4 2 1 0 2 2 2 1 Polysaccharide deacetylase Herpes_gE PF02480.16 PSC76360.1 - 0.16 10.7 0.4 0.23 10.2 0.4 1.1 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Nuc_sug_transp PF04142.15 PSC76361.1 - 6e-50 170.2 15.7 7.5e-50 169.9 15.7 1.1 1 0 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.20 PSC76361.1 - 3.1e-07 30.6 30.1 0.00085 19.5 3.4 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF4512 PF14975.6 PSC76361.1 - 0.1 13.4 0.2 0.17 12.7 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) MFS_1 PF07690.16 PSC76363.1 - 5.3e-45 153.9 31.8 5.3e-45 153.9 31.8 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 PSC76363.1 - 0.0022 16.9 3.5 0.0022 16.9 3.5 1.9 2 0 0 2 2 2 1 Sugar (and other) transporter RRM_1 PF00076.22 PSC76364.1 - 1.5e-39 133.6 0.0 2.9e-15 55.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PSC76364.1 - 7.7e-13 48.4 0.0 0.0014 18.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif Spo7_2_N PF15407.6 PSC76364.1 - 0.00086 18.9 0.0 3.3 7.4 0.0 3.2 3 0 0 3 3 3 2 Sporulation protein family 7 RRM_5 PF13893.6 PSC76364.1 - 0.0068 16.0 0.0 0.012 15.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 PSC76364.1 - 0.048 13.7 0.1 3 7.9 0.0 2.5 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Laminin_G_1 PF00054.23 PSC76364.1 - 0.11 12.7 0.0 7 6.9 0.0 3.0 3 0 0 3 3 3 0 Laminin G domain DUF3801 PF12687.7 PSC76365.1 - 0.088 12.9 2.8 0.087 12.9 1.3 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3801) COG4 PF08318.12 PSC76365.1 - 0.15 11.1 0.8 7.3 5.6 0.0 2.2 2 0 0 2 2 2 0 COG4 transport protein CDK2AP PF09806.9 PSC76365.1 - 1.1 9.3 17.4 0.1 12.6 0.6 2.9 3 0 0 3 3 3 0 Cyclin-dependent kinase 2-associated protein TFIIA PF03153.13 PSC76365.1 - 4.7 7.1 16.8 1.3 8.9 13.6 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF3801 PF12687.7 PSC76366.1 - 0.049 13.7 1.3 0.093 12.8 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) CDK2AP PF09806.9 PSC76366.1 - 0.29 11.2 14.5 0.11 12.5 0.6 2.6 3 0 0 3 3 3 0 Cyclin-dependent kinase 2-associated protein AP2 PF00847.20 PSC76367.1 - 4.6e-15 55.6 10.9 4.3e-08 33.3 1.9 2.8 2 0 0 2 2 2 2 AP2 domain PAT1 PF09770.9 PSC76367.1 - 0.8 7.9 7.6 0.97 7.6 7.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.13 PSC76367.1 - 1.4 8.9 16.4 2.2 8.2 16.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Fumble PF03630.14 PSC76368.1 - 2.8e-131 437.6 0.1 3.6e-131 437.2 0.1 1.1 1 0 0 1 1 1 1 Fumble DUF89 PF01937.19 PSC76368.1 - 5e-34 117.8 0.0 1.9e-29 102.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function DUF89 Fumble PF03630.14 PSC76369.1 - 2.8e-131 437.6 0.1 3.7e-131 437.2 0.1 1.1 1 0 0 1 1 1 1 Fumble DUF89 PF01937.19 PSC76369.1 - 5.2e-34 117.7 0.0 2e-29 102.7 0.0 2.1 2 0 0 2 2 2 2 Protein of unknown function DUF89 2OG-FeII_Oxy_3 PF13640.6 PSC76370.1 - 9e-20 71.4 0.0 1.8e-19 70.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 PSC76370.1 - 8.5e-11 42.2 0.0 1.6e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily zf_CCCH_4 PF18345.1 PSC76370.1 - 0.0001 22.2 1.2 0.0001 22.2 1.2 3.6 4 0 0 4 4 4 1 Zinc finger domain zf-CCCH PF00642.24 PSC76370.1 - 0.00012 21.9 0.3 0.00012 21.9 0.3 3.8 4 0 0 4 4 4 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 PSC76370.1 - 0.0025 17.6 1.3 0.0025 17.6 1.3 3.1 3 0 0 3 3 3 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 PSC76370.1 - 0.011 16.2 18.7 0.012 16.1 2.7 3.5 3 0 0 3 3 3 0 RNA-binding, Nab2-type zinc finger ShK PF01549.24 PSC76370.1 - 0.11 13.0 0.4 0.28 11.8 0.4 1.7 1 0 0 1 1 1 0 ShK domain-like Torus PF16131.5 PSC76370.1 - 0.25 12.1 0.1 0.25 12.1 0.1 2.3 2 0 0 2 2 2 0 Torus domain tRNA-synt_2c PF01411.19 PSC76371.1 - 6.5e-213 708.2 0.0 8.5e-213 707.8 0.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (A) MBOAT_2 PF13813.6 PSC76371.1 - 2.7e-18 66.0 4.0 6.9e-09 35.9 0.2 2.7 2 0 0 2 2 2 2 Membrane bound O-acyl transferase family DHHA1 PF02272.19 PSC76371.1 - 5.9e-15 55.9 3.5 2.7e-14 53.8 3.5 2.1 1 0 0 1 1 1 1 DHHA1 domain tRNA_SAD PF07973.14 PSC76371.1 - 8.3e-15 54.6 0.0 1.9e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain RcbX PF02341.15 PSC76372.1 - 0.014 15.6 0.0 2.3 8.5 0.0 2.3 2 0 0 2 2 2 0 RbcX protein DUF1850 PF08905.11 PSC76372.1 - 0.069 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1850) BOP1NT PF08145.12 PSC76374.1 - 5.3e-100 334.6 4.5 7.1e-100 334.2 4.5 1.2 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 PSC76374.1 - 6.3e-25 87.0 9.5 6.6e-08 33.1 0.1 8.0 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC76374.1 - 7.3e-07 29.4 0.0 0.0017 18.6 0.0 3.8 2 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 PSC76374.1 - 0.066 11.5 0.0 1.4 7.1 0.0 2.5 2 1 1 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz Nop14 PF04147.12 PSC76374.1 - 4.2 5.5 16.4 7.2 4.7 16.4 1.3 1 0 0 1 1 1 0 Nop14-like family GRIP PF01465.20 PSC76375.1 - 7.8e-10 38.5 0.0 2.6e-09 36.8 0.0 2.0 1 0 0 1 1 1 1 GRIP domain TMF_TATA_bd PF12325.8 PSC76375.1 - 0.0086 16.3 1.3 0.0086 16.3 1.3 17.6 8 3 8 19 19 19 2 TATA element modulatory factor 1 TATA binding GRIP PF01465.20 PSC76376.1 - 7.8e-10 38.5 0.0 2.6e-09 36.8 0.0 2.0 1 0 0 1 1 1 1 GRIP domain TMF_TATA_bd PF12325.8 PSC76376.1 - 0.0086 16.3 1.3 0.0086 16.3 1.3 17.6 8 3 8 19 19 19 2 TATA element modulatory factor 1 TATA binding Golgin_A5 PF09787.9 PSC76377.1 - 0.0075 15.8 7.0 0.01 15.3 7.0 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 V_ATPase_I PF01496.19 PSC76377.1 - 0.021 12.7 1.3 0.024 12.6 1.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF4665 PF15679.5 PSC76377.1 - 0.096 13.3 0.7 0.16 12.6 0.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4665) WXG100 PF06013.12 PSC76377.1 - 0.14 12.4 7.3 0.51 10.6 7.3 1.9 1 1 0 1 1 1 0 Proteins of 100 residues with WXG Polyoma_lg_T_C PF06431.11 PSC76377.1 - 0.28 10.0 0.6 0.37 9.6 0.6 1.1 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus CTNNB1_binding PF08347.11 PSC76377.1 - 1 9.5 4.6 1.6 8.9 4.6 1.2 1 0 0 1 1 1 0 N-terminal CTNNB1 binding DUF572 PF04502.13 PSC76377.1 - 1.1 8.8 7.0 1.4 8.5 7.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) MazG-like PF12643.7 PSC76378.1 - 3e-11 43.4 0.0 5.3e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 MazG-like family MazG PF03819.17 PSC76378.1 - 2.1e-05 24.6 0.0 4.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain mTERF PF02536.14 PSC76378.1 - 0.0042 16.1 0.0 0.021 13.7 0.0 2.0 2 1 0 2 2 2 1 mTERF AAA PF00004.29 PSC76379.1 - 5.2e-35 120.7 0.0 9.8e-35 119.9 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PSC76379.1 - 6.6e-07 29.4 0.0 5.5e-06 26.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 PSC76379.1 - 1.7e-05 24.6 0.0 4.5e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PSC76379.1 - 5.8e-05 23.5 0.4 0.0027 18.1 0.1 3.3 3 1 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.6 PSC76379.1 - 0.0012 19.2 0.3 0.094 13.0 0.0 3.1 2 1 1 3 3 3 1 AAA domain AAA_30 PF13604.6 PSC76379.1 - 0.0073 16.0 0.1 0.021 14.6 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 PSC76379.1 - 0.0077 16.3 0.0 0.034 14.2 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 PSC76379.1 - 0.014 15.5 0.0 0.039 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 PSC76379.1 - 0.019 14.8 0.0 0.035 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF815 PF05673.13 PSC76379.1 - 0.024 13.8 0.0 0.07 12.3 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.6 PSC76379.1 - 0.026 15.1 0.0 0.063 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 PSC76379.1 - 0.032 14.5 0.1 0.1 12.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_2 PF07724.14 PSC76379.1 - 0.05 13.7 0.0 0.1 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) NACHT PF05729.12 PSC76379.1 - 0.067 13.1 0.0 0.99 9.3 0.0 2.4 1 1 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 PSC76379.1 - 0.15 11.8 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 PSC76379.1 - 0.16 11.2 0.0 0.36 10.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Rubrerythrin PF02915.17 PSC76381.1 - 3.3e-54 183.0 0.0 7.5e-32 110.6 0.0 2.5 2 0 0 2 2 2 2 Rubrerythrin Exostosin PF03016.15 PSC76381.1 - 3.2e-09 36.4 2.2 5.1e-06 25.9 0.4 2.3 2 0 0 2 2 2 2 Exostosin family AurF PF11583.8 PSC76381.1 - 0.0038 16.6 0.0 4.5 6.5 0.0 3.0 3 0 0 3 3 3 2 P-aminobenzoate N-oxygenase AurF FA_desaturase_2 PF03405.14 PSC76381.1 - 0.0079 15.1 0.0 6.9 5.4 0.0 3.1 3 0 0 3 3 3 2 Fatty acid desaturase Ribonuc_red_sm PF00268.21 PSC76381.1 - 0.031 13.8 0.0 4.9 6.5 0.0 2.5 3 0 0 3 3 3 0 Ribonucleotide reductase, small chain DUF3199 PF11436.8 PSC76381.1 - 0.033 14.2 0.0 8.6 6.4 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3199) Spindle_Spc25 PF08234.12 PSC76381.1 - 0.18 12.0 0.2 22 5.4 0.1 2.6 2 0 0 2 2 2 0 Chromosome segregation protein Spc25 HMG_box PF00505.19 PSC76382.1 - 3e-45 152.5 6.0 7.5e-22 77.5 0.6 2.5 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 PSC76382.1 - 5.4e-35 119.8 8.0 7.6e-17 61.7 1.0 2.6 2 0 0 2 2 2 2 HMG-box domain Usp PF00582.26 PSC76382.1 - 8.2e-07 29.6 0.6 8.2e-07 29.6 0.6 5.7 5 1 0 5 5 5 3 Universal stress protein family YABBY PF04690.13 PSC76382.1 - 7.9e-06 26.5 8.0 0.029 14.9 1.0 2.5 2 0 0 2 2 2 2 YABBY protein HMG_box_5 PF14887.6 PSC76382.1 - 0.084 12.9 4.6 5.9 6.9 0.4 2.7 2 0 0 2 2 2 0 HMG (high mobility group) box 5 BUD22 PF09073.10 PSC76382.1 - 0.28 10.5 45.1 0.053 12.9 17.9 3.1 3 0 0 3 3 3 0 BUD22 SOBP PF15279.6 PSC76382.1 - 0.96 10.0 10.2 4 7.9 1.4 2.4 2 0 0 2 2 2 0 Sine oculis-binding protein Glutaredoxin PF00462.24 PSC76383.1 - 1.2e-08 35.0 0.0 4.1e-08 33.3 0.0 1.9 2 0 0 2 2 2 1 Glutaredoxin TTL PF03133.15 PSC76384.1 - 3.7e-71 239.7 0.0 5.5e-71 239.1 0.0 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 PSC76384.1 - 4.2e-05 22.9 1.2 0.00079 18.7 0.0 2.9 3 1 0 3 3 3 1 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 PSC76384.1 - 0.00098 18.4 0.0 0.004 16.5 0.0 1.8 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Myc_N PF01056.18 PSC76384.1 - 0.52 10.2 3.1 1.6 8.6 3.1 1.8 1 0 0 1 1 1 0 Myc amino-terminal region N2227 PF07942.12 PSC76385.1 - 3.1e-89 298.8 0.0 4.7e-89 298.2 0.0 1.2 1 0 0 1 1 1 1 N2227-like protein Not3 PF04065.15 PSC76385.1 - 1.4e-70 237.4 0.0 2.1e-70 236.8 0.0 1.2 1 0 0 1 1 1 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 PSC76385.1 - 3.9e-22 78.7 0.2 1.1e-21 77.3 0.2 1.7 1 0 0 1 1 1 1 NOT2 / NOT3 / NOT5 family Methyltransf_11 PF08241.12 PSC76385.1 - 0.00051 20.6 0.1 0.0022 18.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Syntaxin_2 PF14523.6 PSC76385.1 - 0.0055 17.1 0.4 0.026 14.9 0.1 2.3 2 1 0 2 2 2 1 Syntaxin-like protein 4HB_MCP_1 PF12729.7 PSC76385.1 - 0.007 15.9 0.9 0.017 14.6 0.9 1.6 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction Methyltransf_12 PF08242.12 PSC76385.1 - 0.011 16.5 0.0 0.033 14.9 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain EcoR124_C PF12008.8 PSC76385.1 - 0.073 12.7 1.3 0.13 11.9 1.3 1.3 1 0 0 1 1 1 0 Type I restriction and modification enzyme - subunit R C terminal Methyltransf_23 PF13489.6 PSC76385.1 - 0.096 12.5 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain GTSE1_N PF15259.6 PSC76385.1 - 2.2 8.4 6.0 5.3 7.2 6.0 1.6 1 0 0 1 1 1 0 G-2 and S-phase expressed 1 ABC_tran PF00005.27 PSC76386.1 - 2.5e-19 70.1 0.0 6.5e-19 68.8 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 PSC76386.1 - 1.3e-08 35.0 2.7 7e-05 22.8 0.2 2.2 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 PSC76386.1 - 0.0018 18.5 0.2 0.0098 16.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 PSC76386.1 - 0.0029 17.1 0.0 0.0055 16.2 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PSC76386.1 - 0.0077 16.6 5.3 0.04 14.3 0.3 2.7 2 1 0 2 2 2 1 AAA ATPase domain AAA_30 PF13604.6 PSC76386.1 - 0.013 15.2 0.0 0.013 15.2 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 PSC76386.1 - 0.018 14.8 0.5 0.053 13.3 0.1 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_23 PF13476.6 PSC76386.1 - 0.018 15.5 0.2 0.053 14.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 PSC76386.1 - 0.024 14.2 0.1 0.084 12.4 0.1 2.0 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.6 PSC76386.1 - 0.038 14.2 2.0 0.11 12.7 0.0 2.7 3 0 0 3 3 3 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 PSC76386.1 - 0.069 13.1 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_13 PF13166.6 PSC76386.1 - 0.22 10.1 0.0 0.39 9.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Serglycin PF04360.12 PSC76386.1 - 0.31 11.0 0.0 0.31 11.0 0.0 2.5 3 0 0 3 3 3 0 Serglycin DLIC PF05783.11 PSC76386.1 - 2.3 6.9 6.1 2.6 6.8 0.0 2.2 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) adh_short PF00106.25 PSC76388.1 - 3.5e-24 85.4 0.0 2.8e-20 72.6 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 PSC76388.1 - 2.4e-15 56.7 0.1 1.3e-14 54.3 0.1 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC76388.1 - 2.2e-08 34.2 0.1 3.8e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PSC76388.1 - 0.0022 17.5 0.1 0.0035 16.8 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family THF_DHG_CYH_C PF02882.19 PSC76388.1 - 0.0079 15.5 0.0 0.014 14.7 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 2-Hacid_dh_C PF02826.19 PSC76388.1 - 0.014 14.7 0.0 0.066 12.6 0.0 1.9 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 PSC76388.1 - 0.16 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Shikimate_DH PF01488.20 PSC76388.1 - 0.22 11.6 0.1 0.46 10.5 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase JmjC PF02373.22 PSC76390.1 - 3e-40 137.2 0.1 5.3e-40 136.4 0.1 1.4 1 0 0 1 1 1 1 JmjC domain, hydroxylase FAD_binding_3 PF01494.19 PSC76390.1 - 5.4e-16 58.8 0.4 1.5e-08 34.3 0.0 2.4 1 1 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.6 PSC76390.1 - 2.2e-06 27.8 0.0 1.2e-05 25.4 0.0 2.4 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain JmjN PF02375.17 PSC76390.1 - 0.00057 19.8 0.0 0.0012 18.8 0.0 1.5 1 0 0 1 1 1 1 jmjN domain Pyr_redox_2 PF07992.14 PSC76390.1 - 0.0012 18.1 0.0 0.0023 17.2 0.0 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 PSC76390.1 - 0.013 14.2 0.1 0.022 13.5 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein Thi4 PF01946.17 PSC76390.1 - 0.032 13.5 0.0 0.064 12.5 0.0 1.4 1 0 0 1 1 1 0 Thi4 family GIDA PF01134.22 PSC76390.1 - 0.082 12.0 0.1 0.13 11.3 0.1 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A CDC45 PF02724.14 PSC76390.1 - 0.65 8.2 6.4 4.9 5.3 7.4 1.9 2 0 0 2 2 2 0 CDC45-like protein ATG16 PF08614.11 PSC76391.1 - 0.00026 21.3 53.4 0.0041 17.4 31.6 3.9 2 1 1 3 3 3 2 Autophagy protein 16 (ATG16) KASH_CCD PF14662.6 PSC76391.1 - 0.0024 17.8 12.6 0.0024 17.8 12.6 2.6 3 0 0 3 3 3 1 Coiled-coil region of CCDC155 or KASH SHE3 PF17078.5 PSC76391.1 - 0.0095 15.7 1.7 0.0095 15.7 1.7 2.5 3 0 0 3 3 3 1 SWI5-dependent HO expression protein 3 DUF3450 PF11932.8 PSC76391.1 - 0.0096 15.3 8.4 0.0096 15.3 8.4 4.4 2 1 1 4 4 4 1 Protein of unknown function (DUF3450) HALZ PF02183.18 PSC76391.1 - 0.017 15.3 0.1 0.017 15.3 0.1 3.8 3 0 0 3 3 3 0 Homeobox associated leucine zipper Fib_alpha PF08702.10 PSC76391.1 - 0.07 13.3 0.2 0.07 13.3 0.2 2.7 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family DivIC PF04977.15 PSC76391.1 - 0.15 11.9 40.7 0.52 10.1 0.4 6.6 3 1 4 7 7 7 0 Septum formation initiator DUF1664 PF07889.12 PSC76391.1 - 0.42 10.7 8.6 8.3 6.5 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) CENP-F_leu_zip PF10473.9 PSC76391.1 - 0.55 10.2 33.5 0.29 11.2 8.4 4.2 3 1 1 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Surfac_D-trimer PF09006.11 PSC76391.1 - 1.9 8.4 9.1 18 5.3 0.2 4.6 4 0 0 4 4 4 0 Lung surfactant protein D coiled-coil trimerisation TSC22 PF01166.18 PSC76391.1 - 3.7 7.9 6.7 1 9.7 0.2 3.2 3 0 0 3 3 3 0 TSC-22/dip/bun family YabA PF06156.13 PSC76391.1 - 4.2 8.1 22.5 0.59 10.8 0.4 4.7 3 1 2 5 5 5 0 Initiation control protein YabA bZIP_1 PF00170.21 PSC76391.1 - 4.6 7.4 25.0 0.53 10.4 0.2 6.1 3 1 3 6 6 6 0 bZIP transcription factor DUF4795 PF16043.5 PSC76391.1 - 8.3 6.0 12.4 1.6 8.3 3.9 3.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) AAA_13 PF13166.6 PSC76391.1 - 10 4.6 15.7 19 3.7 15.7 1.5 1 1 0 1 1 1 0 AAA domain ATG16 PF08614.11 PSC76392.1 - 0.0038 17.5 15.2 0.0038 17.5 15.2 1.9 1 1 1 2 2 2 1 Autophagy protein 16 (ATG16) DUF948 PF06103.11 PSC76392.1 - 0.033 14.5 0.6 0.078 13.2 0.6 1.6 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) Phage_GP20 PF06810.11 PSC76392.1 - 0.049 13.4 3.3 0.074 12.9 2.5 1.6 1 1 1 2 2 2 0 Phage minor structural protein GP20 CDC73_N PF16050.5 PSC76392.1 - 0.18 11.1 2.4 0.28 10.5 2.4 1.3 1 0 0 1 1 1 0 Paf1 complex subunit CDC73 N-terminal Myf5 PF12232.8 PSC76392.1 - 0.21 12.4 6.6 0.83 10.5 6.6 2.1 1 0 0 1 1 1 0 Myogenic determination factor 5 Nsp1_C PF05064.13 PSC76392.1 - 0.29 11.0 4.4 0.56 10.0 4.4 1.4 1 0 0 1 1 1 0 Nsp1-like C-terminal region Peptidase_S46 PF10459.9 PSC76392.1 - 3.6 6.1 5.4 4.7 5.7 5.4 1.1 1 0 0 1 1 1 0 Peptidase S46 COG2 PF06148.11 PSC76392.1 - 4 7.5 7.2 9.8 6.3 7.2 1.6 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 CLZ PF16526.5 PSC76392.1 - 5.6 7.4 12.1 0.12 12.8 4.5 2.1 3 0 0 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels OmpH PF03938.14 PSC76392.1 - 5.7 7.3 12.7 16 5.8 12.5 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) D123 PF07065.14 PSC76393.1 - 1.8e-77 260.5 0.0 8.1e-77 258.4 0.0 1.8 1 1 0 1 1 1 1 D123 R2K_3 PF14243.6 PSC76393.1 - 0.0024 17.9 0.1 0.006 16.6 0.1 1.6 1 0 0 1 1 1 1 ATP-grasp domain, R2K clade family 3 R2K_2 PF18299.1 PSC76393.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 Snf7 PF03357.21 PSC76394.1 - 3.7e-42 143.8 10.0 4.4e-42 143.6 10.0 1.0 1 0 0 1 1 1 1 Snf7 Lectin_N PF03954.14 PSC76394.1 - 0.0058 16.4 2.3 1.4 8.7 1.0 2.2 2 0 0 2 2 2 2 Hepatic lectin, N-terminal domain Atg14 PF10186.9 PSC76394.1 - 0.023 13.8 2.8 0.033 13.3 2.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 PSC76394.1 - 0.08 13.3 10.2 0.6 10.4 7.9 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Glu-tRNAGln PF02686.15 PSC76394.1 - 0.15 12.4 2.4 1.4 9.3 1.5 2.7 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit SlyX PF04102.12 PSC76394.1 - 0.21 12.2 7.2 4.6 7.9 1.1 3.1 4 0 0 4 4 3 0 SlyX Med28 PF11594.8 PSC76394.1 - 0.27 11.3 4.1 0.59 10.2 3.6 1.8 1 1 1 2 2 2 0 Mediator complex subunit 28 FliJ PF02050.16 PSC76394.1 - 0.36 11.0 6.5 0.43 10.8 4.1 2.2 1 1 0 2 2 2 0 Flagellar FliJ protein RPW8 PF05659.11 PSC76394.1 - 0.37 10.5 5.4 0.95 9.2 2.4 2.3 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 XhlA PF10779.9 PSC76394.1 - 0.69 10.2 5.5 0.78 10.0 2.1 2.3 2 0 0 2 2 2 0 Haemolysin XhlA LUC7 PF03194.15 PSC76394.1 - 0.76 9.4 9.3 2.9 7.5 4.0 2.1 1 1 1 2 2 2 0 LUC7 N_terminus Prefoldin PF02996.17 PSC76394.1 - 0.79 9.6 6.8 0.33 10.9 0.6 2.9 1 1 3 4 4 4 0 Prefoldin subunit DUF848 PF05852.11 PSC76394.1 - 0.92 9.6 5.5 0.42 10.7 1.9 2.2 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Prefoldin_2 PF01920.20 PSC76394.1 - 2.3 8.2 10.5 3 7.8 0.2 3.3 2 1 1 3 3 3 0 Prefoldin subunit DUF1664 PF07889.12 PSC76394.1 - 3 7.9 8.1 3 7.9 0.3 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 PSC76394.1 - 4.5 7.5 8.8 4.4 7.6 0.5 2.6 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain BRE1 PF08647.11 PSC76394.1 - 6.8 6.8 10.1 1.2 9.2 0.6 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Snf7 PF03357.21 PSC76395.1 - 3.7e-42 143.8 10.0 4.4e-42 143.6 10.0 1.0 1 0 0 1 1 1 1 Snf7 Lectin_N PF03954.14 PSC76395.1 - 0.0058 16.4 2.3 1.4 8.7 1.0 2.2 2 0 0 2 2 2 2 Hepatic lectin, N-terminal domain Atg14 PF10186.9 PSC76395.1 - 0.023 13.8 2.8 0.033 13.3 2.8 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 OmpH PF03938.14 PSC76395.1 - 0.08 13.3 10.2 0.6 10.4 7.9 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Glu-tRNAGln PF02686.15 PSC76395.1 - 0.15 12.4 2.4 1.4 9.3 1.5 2.7 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit SlyX PF04102.12 PSC76395.1 - 0.21 12.2 7.2 4.6 7.9 1.1 3.1 4 0 0 4 4 3 0 SlyX Med28 PF11594.8 PSC76395.1 - 0.27 11.3 4.1 0.59 10.2 3.6 1.8 1 1 1 2 2 2 0 Mediator complex subunit 28 FliJ PF02050.16 PSC76395.1 - 0.36 11.0 6.5 0.43 10.8 4.1 2.2 1 1 0 2 2 2 0 Flagellar FliJ protein RPW8 PF05659.11 PSC76395.1 - 0.37 10.5 5.4 0.95 9.2 2.4 2.3 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 XhlA PF10779.9 PSC76395.1 - 0.69 10.2 5.5 0.78 10.0 2.1 2.3 2 0 0 2 2 2 0 Haemolysin XhlA LUC7 PF03194.15 PSC76395.1 - 0.76 9.4 9.3 2.9 7.5 4.0 2.1 1 1 1 2 2 2 0 LUC7 N_terminus Prefoldin PF02996.17 PSC76395.1 - 0.79 9.6 6.8 0.33 10.9 0.6 2.9 1 1 3 4 4 4 0 Prefoldin subunit DUF848 PF05852.11 PSC76395.1 - 0.92 9.6 5.5 0.42 10.7 1.9 2.2 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) Prefoldin_2 PF01920.20 PSC76395.1 - 2.3 8.2 10.5 3 7.8 0.2 3.3 2 1 1 3 3 3 0 Prefoldin subunit DUF1664 PF07889.12 PSC76395.1 - 3 7.9 8.1 3 7.9 0.3 2.7 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 PSC76395.1 - 4.5 7.5 8.8 4.4 7.6 0.5 2.6 1 1 1 3 3 3 0 Seryl-tRNA synthetase N-terminal domain BRE1 PF08647.11 PSC76395.1 - 6.8 6.8 10.1 1.2 9.2 0.6 2.5 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase ABC_tran PF00005.27 PSC76396.1 - 2.2e-33 115.7 0.0 5.5e-33 114.4 0.0 1.6 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 PSC76396.1 - 1.6e-07 31.4 0.0 0.00021 21.2 0.0 2.1 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system TOBE_2 PF08402.10 PSC76396.1 - 4.8e-06 26.7 0.1 1.3e-05 25.2 0.1 1.8 1 0 0 1 1 1 1 TOBE domain AAA_29 PF13555.6 PSC76396.1 - 0.00023 20.9 0.0 0.00043 20.0 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 PSC76396.1 - 0.0011 18.4 0.0 0.74 9.2 0.0 2.2 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 PSC76396.1 - 0.0025 18.2 0.0 0.0035 17.7 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 PSC76396.1 - 0.006 17.1 0.0 0.01 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 PSC76396.1 - 0.013 15.8 0.0 0.027 14.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 PSC76396.1 - 0.015 15.2 0.0 0.028 14.3 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_25 PF13481.6 PSC76396.1 - 0.017 14.7 0.1 0.19 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_ATPase PF09818.9 PSC76396.1 - 0.017 13.9 0.1 1.7 7.4 0.0 2.6 2 1 0 2 2 2 0 Predicted ATPase of the ABC class AAA_33 PF13671.6 PSC76396.1 - 0.029 14.5 0.0 0.12 12.5 0.0 2.0 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 PSC76396.1 - 0.029 14.4 0.0 0.066 13.3 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.12 PSC76396.1 - 0.045 13.7 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 PSC76396.1 - 0.046 13.4 0.0 0.096 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 PSC76396.1 - 0.052 13.5 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea AAA_18 PF13238.6 PSC76396.1 - 0.09 13.3 0.0 0.17 12.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain cobW PF02492.19 PSC76396.1 - 0.091 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 PSC76396.1 - 0.11 12.8 0.1 0.6 10.4 0.1 2.1 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_14 PF13173.6 PSC76396.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PSC76396.1 - 0.14 12.4 0.0 0.7 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_15 PF13175.6 PSC76396.1 - 0.23 11.1 0.0 0.43 10.2 0.0 1.4 2 0 0 2 2 2 0 AAA ATPase domain adh_short PF00106.25 PSC76397.1 - 4.2e-18 65.5 0.0 5.6e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC76397.1 - 7.5e-14 51.8 0.0 9e-14 51.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF525 PF04379.14 PSC76398.1 - 2.1e-23 82.4 0.0 3.4e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 ApaG domain SMI1_KNR4 PF09346.10 PSC76398.1 - 3.5e-06 27.4 0.0 5.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) GvpL_GvpF PF06386.11 PSC76398.1 - 0.0074 16.3 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 Gas vesicle synthesis protein GvpL/GvpF DUF525 PF04379.14 PSC76399.1 - 2.1e-23 82.4 0.0 3.4e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 ApaG domain SMI1_KNR4 PF09346.10 PSC76399.1 - 3.5e-06 27.4 0.0 5.1e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 SMI1 / KNR4 family (SUKH-1) GvpL_GvpF PF06386.11 PSC76399.1 - 0.0073 16.3 0.1 0.011 15.7 0.1 1.2 1 0 0 1 1 1 1 Gas vesicle synthesis protein GvpL/GvpF AAA_5 PF07728.14 PSC76400.1 - 1.1e-24 87.1 0.0 1.9e-24 86.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_lid_8 PF17868.1 PSC76400.1 - 2.8e-15 55.9 0.0 2.4e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 AAA lid domain AAA_3 PF07726.11 PSC76400.1 - 5.2e-05 23.1 0.0 0.0001 22.1 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 PSC76400.1 - 0.0005 19.5 0.1 0.0016 17.8 0.0 1.8 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 PSC76400.1 - 0.008 16.6 0.5 0.008 16.6 0.5 2.8 3 1 0 3 3 3 1 AAA ATPase domain AAA PF00004.29 PSC76400.1 - 0.0086 16.5 0.0 0.02 15.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 PSC76400.1 - 0.091 12.5 0.1 1.5 8.6 0.1 2.3 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain PAC2 PF09754.9 PSC76401.1 - 9.7e-21 74.8 0.0 1.3e-20 74.3 0.0 1.3 1 1 0 1 1 1 1 PAC2 family DUF1350 PF07082.11 PSC76402.1 - 1.9e-55 187.8 0.1 5.2e-36 124.2 0.0 2.1 1 1 0 2 2 2 2 Protein of unknown function (DUF1350) Hydrolase_4 PF12146.8 PSC76402.1 - 0.071 12.4 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 CwfJ_C_1 PF04677.15 PSC76403.1 - 7.7e-26 90.4 0.0 1.2e-25 89.7 0.0 1.2 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 Pectate_lyase_3 PF12708.7 PSC76403.1 - 2.3e-15 57.1 2.7 8.2e-15 55.2 0.0 2.5 2 0 0 2 2 2 1 Pectate lyase superfamily protein RRM_1 PF00076.22 PSC76403.1 - 8.5e-15 54.3 0.0 1.7e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CwfJ_C_2 PF04676.14 PSC76403.1 - 6.2e-06 27.0 0.0 1.4e-05 25.9 0.0 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 2 DUF3494 PF11999.8 PSC76403.1 - 0.035 13.7 1.5 0.1 12.2 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3494) Nup35_RRM PF05172.13 PSC76403.1 - 0.089 12.8 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif End_N_terminal PF12218.8 PSC76403.1 - 0.095 12.4 1.5 0.32 10.7 0.4 2.4 2 0 0 2 2 2 0 N terminal extension of bacteriophage endosialidase Hydrolase PF00702.26 PSC76404.1 - 1.2e-14 55.1 0.0 5.2e-14 53.0 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 PSC76404.1 - 1.9e-14 54.1 0.0 7.7e-14 52.2 0.0 1.8 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 PSC76404.1 - 6.3e-07 29.4 0.0 1.2e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like HAD PF12710.7 PSC76404.1 - 3.3e-06 27.6 0.0 4.7e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_6 PF13344.6 PSC76404.1 - 0.0017 18.4 0.0 0.26 11.4 0.0 3.0 3 0 0 3 3 3 1 Haloacid dehalogenase-like hydrolase AMP-binding PF00501.28 PSC76405.1 - 1e-73 248.3 0.1 6e-71 239.2 0.0 2.5 2 1 0 2 2 2 2 AMP-binding enzyme ACAS_N PF16177.5 PSC76405.1 - 8.8e-22 76.8 1.3 2.4e-21 75.4 1.3 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 PSC76405.1 - 2e-21 76.7 0.1 4.1e-21 75.7 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pyr_redox_2 PF07992.14 PSC76406.1 - 1.8e-43 148.9 0.0 2.9e-43 148.2 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 PSC76406.1 - 8e-17 61.4 0.1 4.3e-15 55.7 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PSC76406.1 - 1e-14 54.8 0.3 1.4e-12 48.0 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 PSC76406.1 - 0.00036 20.9 0.0 0.023 15.1 0.0 2.4 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 PSC76406.1 - 0.0051 16.1 0.0 0.015 14.6 0.0 1.7 2 0 0 2 2 2 1 Thi4 family zf-C2H2 PF00096.26 PSC76406.1 - 0.015 15.7 6.9 0.062 13.8 0.3 2.5 2 0 0 2 2 2 0 Zinc finger, C2H2 type NAD_binding_8 PF13450.6 PSC76406.1 - 0.017 15.3 0.0 0.056 13.7 0.0 1.9 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain zf-C2H2_4 PF13894.6 PSC76406.1 - 0.091 13.7 6.8 3.1 8.9 1.8 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger HI0933_like PF03486.14 PSC76406.1 - 0.13 11.0 1.2 8.7 4.9 0.4 2.9 4 0 0 4 4 4 0 HI0933-like protein FAD_binding_3 PF01494.19 PSC76406.1 - 0.13 11.5 0.2 5.1 6.3 0.2 2.2 2 0 0 2 2 2 0 FAD binding domain GIDA PF01134.22 PSC76406.1 - 0.18 10.9 3.4 21 4.1 0.7 3.6 4 0 0 4 4 4 0 Glucose inhibited division protein A TFIIA PF03153.13 PSC76406.1 - 0.36 10.8 3.8 0.54 10.2 3.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C2H2_jaz PF12171.8 PSC76406.1 - 0.58 10.5 3.7 0.89 9.9 0.0 2.4 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding NDUFB11 PF17250.2 PSC76407.1 - 2e-11 44.4 0.0 3.2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase 11 kDa subunit Med26 PF08711.11 PSC76407.1 - 1.8e-05 24.7 0.1 3.5e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 TFIIS helical bundle-like domain CysG_dimeriser PF10414.9 PSC76407.1 - 0.017 14.8 2.4 0.053 13.2 0.5 2.3 2 0 0 2 2 2 0 Sirohaem synthase dimerisation region Pap_E4 PF02711.14 PSC76407.1 - 0.051 14.6 2.2 0.14 13.1 2.2 1.8 1 0 0 1 1 1 0 E4 protein CAP_N PF01213.19 PSC76407.1 - 0.23 10.9 13.2 0.084 12.3 6.9 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal GCV_T PF01571.21 PSC76409.1 - 3.2e-07 30.0 0.0 8.2e-07 28.6 0.0 1.6 2 0 0 2 2 2 1 Aminomethyltransferase folate-binding domain RRM_1 PF00076.22 PSC76410.1 - 6.9e-18 64.2 0.0 1.4e-17 63.2 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rxt3 PF08642.10 PSC76410.1 - 4.2e-15 56.6 7.7 7e-12 46.2 0.0 3.6 2 1 1 3 3 3 2 Histone deacetylation protein Rxt3 RRM_7 PF16367.5 PSC76410.1 - 0.00024 21.2 0.0 0.0009 19.3 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif LCCL PF03815.19 PSC76410.1 - 0.00048 20.2 0.0 0.00092 19.3 0.0 1.4 1 0 0 1 1 1 1 LCCL domain Med19 PF10278.9 PSC76410.1 - 0.0015 18.5 6.4 0.0031 17.5 6.4 1.4 1 0 0 1 1 1 1 Mediator of RNA pol II transcription subunit 19 DUF3807 PF12720.7 PSC76410.1 - 0.31 11.3 12.9 0.034 14.4 8.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) DUF755 PF05501.11 PSC76410.1 - 0.52 10.6 13.8 1.2 9.4 13.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF755) DUF2828 PF11443.8 PSC76410.1 - 0.88 7.6 3.1 1.2 7.1 3.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) NPR3 PF03666.13 PSC76410.1 - 1.5 7.5 10.4 2.3 6.9 10.4 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Connexin PF00029.19 PSC76410.1 - 1.7 8.4 3.4 2.8 7.6 3.4 1.3 1 0 0 1 1 1 0 Connexin IHABP4_N PF16174.5 PSC76410.1 - 6.2 7.4 28.4 0.36 11.4 21.7 2.2 2 0 0 2 2 2 0 Intracellular hyaluronan-binding protein 4 N-terminal His_Phos_2 PF00328.22 PSC76411.1 - 8.9e-97 324.8 0.0 1.6e-50 172.6 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) PPIP5K2_N PF18086.1 PSC76411.1 - 4.5e-39 132.5 0.0 8.6e-39 131.6 0.0 1.5 1 0 0 1 1 1 1 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain RimK PF08443.11 PSC76411.1 - 0.0089 15.6 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 RimK-like ATP-grasp domain Cpn60_TCP1 PF00118.24 PSC76412.1 - 2.2e-154 514.7 0.2 2.5e-154 514.5 0.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Phage_holin_7_1 PF16081.5 PSC76412.1 - 6.4 7.0 8.6 0.91 9.7 0.2 3.1 3 1 0 3 3 3 0 Mycobacterial 2 TMS Phage Holin (M2 Hol) Family FUSC_2 PF13515.6 PSC76413.1 - 1.4e-08 34.9 15.0 1.4e-08 34.9 15.0 4.0 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 PSC76413.1 - 1.3e-07 30.8 9.5 1.3e-07 30.8 9.5 2.1 2 1 0 2 2 2 1 Aluminium activated malate transporter RRM_1 PF00076.22 PSC76413.1 - 6.3e-06 25.9 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ArAE_2_N PF10337.9 PSC76413.1 - 0.027 13.5 0.1 0.027 13.5 0.1 2.0 3 0 0 3 3 3 0 Putative ER transporter, 6TM, N-terminal RRM_3 PF08777.11 PSC76413.1 - 0.054 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif SUIM_assoc PF16619.5 PSC76413.1 - 0.089 12.9 3.1 0.18 11.9 3.1 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 PSC76413.1 - 5.6 6.8 9.8 9.7 6.1 9.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FUSC_2 PF13515.6 PSC76414.1 - 1.4e-08 34.9 15.0 1.4e-08 34.9 15.0 4.0 2 1 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 PSC76414.1 - 1.3e-07 30.8 9.5 1.3e-07 30.8 9.5 2.0 2 1 0 2 2 2 1 Aluminium activated malate transporter RRM_1 PF00076.22 PSC76414.1 - 6.3e-06 25.9 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) ArAE_2_N PF10337.9 PSC76414.1 - 0.027 13.5 0.1 0.027 13.5 0.1 2.0 3 0 0 3 3 3 0 Putative ER transporter, 6TM, N-terminal RRM_3 PF08777.11 PSC76414.1 - 0.054 13.5 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif SUIM_assoc PF16619.5 PSC76414.1 - 0.089 12.9 3.1 0.18 11.9 3.1 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 PSC76414.1 - 5.6 6.8 9.8 9.7 6.1 9.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Peptidase_C54 PF03416.19 PSC76415.1 - 3.1e-68 230.2 0.0 3e-51 174.4 0.0 2.6 2 0 0 2 2 2 2 Peptidase family C54 Sec23_trunk PF04811.15 PSC76415.1 - 1 8.9 4.8 0.12 11.9 0.4 1.6 2 0 0 2 2 2 0 Sec23/Sec24 trunk domain WD40 PF00400.32 PSC76416.1 - 1.5e-28 98.5 9.0 7.1e-05 23.5 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC76416.1 - 4.8e-18 65.3 1.3 1.4e-06 28.5 0.2 4.4 3 1 1 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ank_2 PF12796.7 PSC76416.1 - 7.5e-14 52.1 0.2 7.1e-10 39.3 0.3 2.5 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC76416.1 - 1.5e-07 31.8 0.2 3e-05 24.5 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC76416.1 - 9.8e-06 25.6 3.0 2 9.2 0.0 4.5 4 0 0 4 4 4 2 Ankyrin repeat eIF2A PF08662.11 PSC76416.1 - 2.2e-05 24.4 0.0 0.014 15.3 0.0 2.8 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A Ank_5 PF13857.6 PSC76416.1 - 3.2e-05 24.1 1.7 0.044 14.1 0.3 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.30 PSC76416.1 - 0.00034 20.9 8.2 0.12 12.9 0.1 4.3 5 0 0 5 5 5 2 Ankyrin repeat Nup160 PF11715.8 PSC76416.1 - 0.093 11.4 0.1 0.15 10.7 0.1 1.2 1 0 0 1 1 1 0 Nucleoporin Nup120/160 DUF4407 PF14362.6 PSC76417.1 - 0.0017 17.8 1.4 0.0017 17.8 1.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4407) Prefoldin_2 PF01920.20 PSC76417.1 - 0.1 12.5 0.8 0.16 11.9 0.1 1.7 2 0 0 2 2 2 0 Prefoldin subunit GAS PF13851.6 PSC76417.1 - 0.21 10.9 3.8 0.15 11.4 1.1 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding Complex1_LYR PF05347.15 PSC76418.1 - 0.012 15.6 0.1 0.027 14.5 0.1 1.6 2 0 0 2 2 2 0 Complex 1 protein (LYR family) Paf67 PF10255.9 PSC76421.1 - 4.4e-124 414.5 0.0 5.3e-124 414.3 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 PCI PF01399.27 PSC76421.1 - 0.019 15.5 0.1 2.1 8.9 0.1 2.9 3 0 0 3 3 3 0 PCI domain Actin PF00022.19 PSC76422.1 - 5.1e-148 493.0 0.0 1.7e-147 491.3 0.0 1.7 1 1 0 1 1 1 1 Actin KDZ PF18758.1 PSC76423.1 - 2.7e-24 86.0 1.7 3.8e-24 85.6 1.7 1.2 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase TAP42 PF04177.12 PSC76424.1 - 1.3e-70 238.0 0.0 1.5e-70 237.9 0.0 1.0 1 0 0 1 1 1 1 TAP42-like family DUF1151 PF06625.11 PSC76424.1 - 3.4 7.6 9.1 0.53 10.2 3.1 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1151) S1 PF00575.23 PSC76425.1 - 8.1e-19 67.8 2.0 1.6e-09 37.9 0.3 2.5 2 1 0 2 2 2 2 S1 RNA binding domain S1_2 PF13509.6 PSC76425.1 - 0.0027 17.7 0.0 0.2 11.7 0.0 2.8 2 1 0 2 2 2 1 S1 domain PCB_OB PF17092.5 PSC76425.1 - 0.0055 17.4 0.0 0.91 10.3 0.0 2.2 2 0 0 2 2 2 2 Penicillin-binding protein OB-like domain p450 PF00067.22 PSC76426.1 - 1.2e-47 162.7 0.0 7.6e-36 123.8 0.0 2.7 2 1 0 2 2 2 2 Cytochrome P450 Fasciclin PF02469.22 PSC76426.1 - 0.019 15.2 0.7 0.072 13.3 0.7 1.9 1 1 0 1 1 1 0 Fasciclin domain p450 PF00067.22 PSC76427.1 - 2.9e-49 168.1 0.0 1.9e-25 89.6 0.0 3.1 3 0 0 3 3 3 3 Cytochrome P450 Fasciclin PF02469.22 PSC76427.1 - 0.019 15.2 0.6 0.071 13.3 0.6 1.9 1 1 0 1 1 1 0 Fasciclin domain p450 PF00067.22 PSC76428.1 - 3e-53 181.2 0.0 7.3e-42 143.7 0.0 2.1 2 0 0 2 2 2 2 Cytochrome P450 Fasciclin PF02469.22 PSC76428.1 - 0.019 15.2 0.7 0.072 13.3 0.7 1.9 1 1 0 1 1 1 0 Fasciclin domain DUF2415 PF10313.9 PSC76429.1 - 8.3e-11 41.6 0.1 2.5e-10 40.1 0.1 1.8 1 0 0 1 1 1 1 Uncharacterised protein domain (DUF2415) ANAPC4_WD40 PF12894.7 PSC76429.1 - 7.7e-08 32.5 0.0 0.037 14.3 0.0 3.3 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PSC76429.1 - 4e-07 30.6 5.4 0.0083 17.0 0.8 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat PQQ_3 PF13570.6 PSC76429.1 - 0.0028 18.1 1.8 0.12 12.9 0.1 3.3 3 0 0 3 3 3 1 PQQ-like domain RETICULATA-like PF11891.8 PSC76430.1 - 7.9e-55 185.4 0.8 2.2e-54 184.0 0.8 1.8 1 0 0 1 1 1 1 Protein RETICULATA-related TFIIIC_delta PF12657.7 PSC76430.1 - 4.5e-12 46.3 0.0 4.5e-12 46.3 0.0 2.7 3 1 0 3 3 3 1 Transcription factor IIIC subunit delta N-term Agenet PF05641.12 PSC76430.1 - 9.9e-12 45.2 0.0 3.1e-11 43.6 0.0 1.9 1 0 0 1 1 1 1 Agenet domain BT1 PF03092.16 PSC76431.1 - 4.8e-94 315.5 13.7 1.5e-90 304.0 13.7 2.8 1 1 0 1 1 1 1 BT1 family MFS_1 PF07690.16 PSC76431.1 - 5.6e-12 45.3 40.3 1.9e-11 43.5 38.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily RRXRR PF14239.6 PSC76432.1 - 0.016 15.1 0.5 1 9.2 0.0 2.4 2 0 0 2 2 2 0 RRXRR protein HrpB7 PF09486.10 PSC76432.1 - 0.13 12.6 14.2 0.9 9.9 3.9 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) Romo1 PF10247.9 PSC76433.1 - 2e-20 72.9 3.8 2.2e-20 72.8 3.8 1.0 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 PSC76433.1 - 0.0016 18.8 3.2 0.0017 18.7 3.2 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_YMGG PF13441.6 PSC76433.1 - 0.0044 16.7 3.9 0.0044 16.7 3.9 1.8 2 0 0 2 2 2 1 YMGG-like Gly-zipper Gly-zipper_Omp PF13488.6 PSC76433.1 - 0.005 16.8 5.6 0.005 16.8 5.6 1.9 2 0 0 2 2 2 1 Glycine zipper Gly-zipper_OmpA PF13436.6 PSC76433.1 - 0.0066 16.2 4.0 0.0066 16.2 4.0 1.9 2 0 0 2 2 2 1 Glycine-zipper domain BclA_C PF18573.1 PSC76433.1 - 0.11 12.4 0.1 0.12 12.3 0.1 1.2 1 0 0 1 1 1 0 BclA C-terminal domain PAS PF00989.25 PSC76434.1 - 4.6e-12 45.9 0.0 3.4e-06 27.0 0.0 4.4 4 1 1 5 5 5 2 PAS fold Fasciclin PF02469.22 PSC76434.1 - 1.9e-11 44.3 0.0 3.6e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Fasciclin domain PAS_9 PF13426.7 PSC76434.1 - 1.2e-10 41.6 0.0 0.0001 22.5 0.0 3.6 3 0 0 3 3 3 2 PAS domain PAS_4 PF08448.10 PSC76434.1 - 1.9e-06 28.1 0.0 0.0015 18.8 0.0 3.5 3 0 0 3 3 3 1 PAS fold PAS_8 PF13188.7 PSC76434.1 - 0.00042 20.3 0.0 0.0025 17.8 0.0 2.3 2 0 0 2 2 2 1 PAS domain PAS_12 PF18095.1 PSC76434.1 - 0.18 11.4 0.0 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 UPF0242 C-terminal PAS-like domain DND1_DSRM PF14709.7 PSC76435.1 - 1.4e-06 28.5 0.2 0.076 13.3 0.0 2.9 2 1 0 2 2 2 2 double strand RNA binding domain from DEAD END PROTEIN 1 CBAH PF02275.18 PSC76435.1 - 0.00011 21.9 0.0 0.00023 20.9 0.0 1.4 1 0 0 1 1 1 1 Linear amide C-N hydrolases, choloylglycine hydrolase family dsRBD2 PF17842.1 PSC76435.1 - 0.00063 20.0 0.0 0.0014 18.8 0.0 1.5 1 0 0 1 1 1 1 Double-stranded RNA binding domain 2 NUDIX PF00293.28 PSC76435.1 - 0.07 13.2 0.1 0.21 11.7 0.1 1.7 1 0 0 1 1 1 0 NUDIX domain NUP50 PF08911.11 PSC76436.1 - 1.1e-14 54.8 0.8 1.1e-14 54.8 0.8 2.9 2 0 0 2 2 2 1 NUP50 (Nucleoporin 50 kDa) Ran_BP1 PF00638.18 PSC76436.1 - 2.6e-14 53.5 0.0 1.7e-13 50.9 0.0 2.0 2 0 0 2 2 2 1 RanBP1 domain DCAF15_WD40 PF14939.6 PSC76438.1 - 2.2e-11 43.8 0.0 4.9e-11 42.7 0.0 1.5 1 1 0 1 1 1 1 DDB1-and CUL4-substrate receptor 15, WD repeat V-ATPase_H_N PF03224.14 PSC76439.1 - 1.4e-60 205.2 0.0 6.2e-58 196.6 0.0 2.9 2 1 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 PSC76439.1 - 6.8e-38 129.4 0.0 6.5e-37 126.2 0.0 2.4 2 0 0 2 2 2 1 V-ATPase subunit H DRIM PF07539.12 PSC76439.1 - 0.0025 16.2 0.0 0.16 10.3 0.0 2.4 2 0 0 2 2 2 2 Down-regulated in metastasis RIX1 PF08167.12 PSC76439.1 - 0.046 13.5 0.3 16 5.2 0.0 3.1 3 0 0 3 3 3 0 rRNA processing/ribosome biogenesis Arm PF00514.23 PSC76439.1 - 0.072 13.2 10.9 6.7 6.9 0.0 5.3 5 1 1 6 6 6 0 Armadillo/beta-catenin-like repeat HEAT PF02985.22 PSC76439.1 - 0.082 13.2 3.2 1.2 9.5 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat PI31_Prot_N PF11566.8 PSC76440.1 - 0.18 11.6 0.0 0.25 11.1 0.0 1.2 1 0 0 1 1 1 0 PI31 proteasome regulator N-terminal Ephrin_rec_like PF07699.13 PSC76441.1 - 1.2e-88 290.7 297.7 9.4e-07 28.5 2.8 30.9 13 6 16 31 31 31 25 Putative ephrin-receptor like NOG1_N PF17835.1 PSC76441.1 - 5.3e-43 146.8 0.1 3.2e-34 118.2 0.0 2.3 2 0 0 2 2 2 2 NOG1 N-terminal helical domain NOG1 PF06858.14 PSC76441.1 - 8.5e-41 137.5 0.0 5.9e-19 67.6 0.0 2.5 2 0 0 2 2 2 2 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 PSC76441.1 - 2.3e-31 108.2 0.0 2e-16 60.1 0.0 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 PSC76441.1 - 1.3e-16 60.6 0.0 9.6e-09 35.0 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B NCD3G PF07562.14 PSC76441.1 - 1.3e-12 47.5 233.9 0.24 11.4 1.9 29.1 18 8 10 32 32 32 19 Nine Cysteines Domain of family 3 GPCR pPIWI_RE_Y PF18156.1 PSC76441.1 - 0.00051 20.5 7.0 0.23 11.9 1.2 2.7 2 0 0 2 2 2 2 pPIWI_RE three-gene island domain Y RsgA_GTPase PF03193.16 PSC76441.1 - 0.00063 19.7 0.0 1 9.3 0.0 3.2 4 0 0 4 4 4 2 RsgA GTPase AAA_18 PF13238.6 PSC76441.1 - 0.00094 19.7 0.0 1.5 9.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 PSC76441.1 - 0.0013 19.1 9.5 0.96 9.8 0.0 4.4 4 0 0 4 4 4 2 AAA ATPase domain GBP_PSP PF02425.15 PSC76441.1 - 0.0046 16.6 3.6 2.6 7.8 0.3 3.5 2 0 0 2 2 2 2 Paralytic/GBP/PSP peptide Roc PF08477.13 PSC76441.1 - 0.03 14.5 0.0 16 5.7 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 PSC76441.1 - 0.076 13.4 0.0 24 5.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase zf_Hakai PF18408.1 PSC76441.1 - 0.076 12.7 0.3 21 4.9 0.1 2.7 2 0 0 2 2 2 0 C2H2 Hakai zinc finger domain TniB PF05621.11 PSC76441.1 - 0.17 11.3 0.0 23 4.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein TACI-CRD2 PF09305.10 PSC76441.1 - 0.37 10.8 9.8 12 6.0 0.3 5.9 3 0 0 3 3 3 0 TACI, cysteine-rich domain Flagellin_IN PF07196.13 PSC76441.1 - 0.7 10.1 13.9 5.8 7.2 3.1 2.9 2 0 0 2 2 2 0 Flagellin hook IN motif TFIIA PF03153.13 PSC76441.1 - 0.96 9.4 34.5 3.6 7.5 13.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 PSC76441.1 - 5.8 6.2 28.3 8.4 5.6 10.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) DUF572 PF04502.13 PSC76441.1 - 6.6 6.3 10.3 11 5.6 1.4 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF572) Reprolysin_5 PF13688.6 PSC76442.1 - 5.9e-08 33.1 0.4 1.1e-07 32.2 0.4 1.4 1 0 0 1 1 1 1 Metallo-peptidase family M12 Reprolysin_3 PF13582.6 PSC76442.1 - 1.4e-05 25.6 0.0 2.7e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 Metallo-peptidase family M12B Reprolysin-like PPC PF04151.15 PSC76442.1 - 0.00071 20.6 0.8 0.00071 20.6 0.8 3.4 3 1 0 3 3 3 1 Bacterial pre-peptidase C-terminal domain Peptidase_M66 PF10462.9 PSC76442.1 - 0.0013 17.8 2.0 0.0023 16.9 2.0 1.5 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_4 PF13583.6 PSC76442.1 - 0.0037 16.9 1.2 0.0061 16.2 0.6 1.7 2 0 0 2 2 2 1 Metallo-peptidase family M12B Reprolysin-like Reprolysin_2 PF13574.6 PSC76442.1 - 0.022 14.7 0.3 0.039 13.8 0.3 1.3 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin PF01421.19 PSC76442.1 - 0.13 12.2 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Reprolysin (M12B) family zinc metalloprotease PRIMA1 PF16101.5 PSC76442.1 - 0.2 11.7 10.3 0.45 10.6 10.3 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Conotoxin_I2 PF17557.2 PSC76442.1 - 0.77 9.9 7.8 1.2 9.3 7.8 1.3 1 0 0 1 1 1 0 I2-superfamily conotoxins CAP_N PF01213.19 PSC76442.1 - 6.8 6.1 4.7 15 4.9 4.7 1.5 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal WD40 PF00400.32 PSC76443.1 - 1.9e-09 38.0 7.1 0.00022 22.0 0.0 4.2 3 0 0 3 3 3 2 WD domain, G-beta repeat Sulfotransfer_2 PF03567.14 PSC76443.1 - 1.5e-06 28.4 0.5 8.7e-06 25.8 0.5 2.0 1 1 0 1 1 1 1 Sulfotransferase family Nup160 PF11715.8 PSC76443.1 - 0.0022 16.7 0.0 0.0051 15.5 0.0 1.6 1 0 0 1 1 1 1 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 PSC76443.1 - 0.019 15.2 0.0 0.34 11.2 0.0 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain HTH_15 PF12324.8 PSC76444.1 - 0.0078 16.1 0.2 0.016 15.2 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain of alkylmercury lyase FAST_1 PF06743.15 PSC76446.1 - 0.0015 18.4 0.1 0.025 14.5 0.0 3.0 4 0 0 4 4 4 1 FAST kinase-like protein, subdomain 1 GSDH PF07995.11 PSC76447.1 - 0.0075 15.6 0.0 0.068 12.5 0.0 2.6 4 0 0 4 4 4 1 Glucose / Sorbosone dehydrogenase NHL PF01436.21 PSC76447.1 - 0.028 14.5 0.0 0.91 9.7 0.0 3.0 3 0 0 3 3 3 0 NHL repeat GPI-anchored PF10342.9 PSC76448.1 - 0.0001 23.0 0.0 0.0032 18.2 0.0 2.1 2 0 0 2 2 2 1 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family VSP PF03302.13 PSC76449.1 - 0.00019 20.4 95.4 0.043 12.7 16.8 4.9 1 1 4 5 5 5 4 Giardia variant-specific surface protein PCI PF01399.27 PSC76450.1 - 1.2e-08 35.4 0.0 4.4e-08 33.6 0.0 2.0 1 0 0 1 1 1 1 PCI domain DUF1499 PF07386.11 PSC76451.1 - 1.6e-28 99.6 0.1 1.9e-28 99.4 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1499) CN_hydrolase PF00795.22 PSC76452.1 - 1.9e-50 171.7 0.0 3.6e-50 170.7 0.0 1.5 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Cellulase PF00150.18 PSC76452.1 - 8.6e-12 45.1 0.1 1.3e-11 44.5 0.1 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) EGF_3 PF12947.7 PSC76452.1 - 1.5e-06 28.2 8.1 3.3e-06 27.2 8.1 1.6 1 0 0 1 1 1 1 EGF domain EGF_CA PF07645.15 PSC76452.1 - 9.1e-06 25.8 6.6 9.1e-06 25.8 6.6 2.2 2 0 0 2 2 2 1 Calcium-binding EGF domain Glyco_hydro_42 PF02449.15 PSC76452.1 - 0.0065 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 Beta-galactosidase EGF_MSP1_1 PF12946.7 PSC76452.1 - 0.074 13.1 8.0 0.18 11.9 8.0 1.7 1 0 0 1 1 1 0 MSP1 EGF domain 1 Frankia_peptide PF14407.6 PSC76452.1 - 0.11 12.5 0.0 0.47 10.5 0.0 2.0 2 0 0 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. EGF PF00008.27 PSC76452.1 - 0.51 10.7 3.6 1.7 9.1 3.6 2.0 1 0 0 1 1 1 0 EGF-like domain FXa_inhibition PF14670.6 PSC76452.1 - 8.6 6.7 10.8 2.6 8.4 6.7 2.2 2 0 0 2 2 2 0 Coagulation Factor Xa inhibitory site NIF PF03031.18 PSC76453.1 - 6.1e-48 162.5 0.0 8.8e-48 162.0 0.0 1.2 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase TPT PF03151.16 PSC76453.1 - 4.5e-19 68.9 9.3 5.9e-19 68.5 9.3 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family Complex1_LYR PF05347.15 PSC76453.1 - 1.1e-07 31.7 0.3 2e-07 30.9 0.3 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) PDH PF02153.17 PSC76454.1 - 1.6e-19 69.9 0.0 2.3e-19 69.4 0.0 1.1 1 0 0 1 1 1 1 Prephenate dehydrogenase F420_oxidored PF03807.17 PSC76454.1 - 2.3e-12 47.3 0.0 5.6e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 PSC76454.1 - 9.2e-07 29.2 0.0 2.1e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 2-Hacid_dh_C PF02826.19 PSC76454.1 - 2.3e-05 23.8 0.0 4.6e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Rossmann-like PF10727.9 PSC76454.1 - 0.00084 19.2 0.0 0.0016 18.3 0.0 1.5 1 0 0 1 1 1 1 Rossmann-like domain ApbA PF02558.16 PSC76454.1 - 0.013 15.1 0.0 0.028 14.1 0.0 1.6 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 PSC76454.1 - 0.026 14.4 0.0 0.061 13.2 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 PSC76454.1 - 0.039 14.8 0.0 0.096 13.5 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold NAD_Gly3P_dh_N PF01210.23 PSC76454.1 - 0.06 13.3 0.0 0.14 12.1 0.0 1.6 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Shikimate_DH PF01488.20 PSC76454.1 - 0.088 12.9 0.0 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase zf-RING_2 PF13639.6 PSC76455.1 - 2.9e-11 43.5 4.9 4e-11 43.1 4.9 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 PSC76455.1 - 6.1e-09 35.6 5.1 9.3e-09 35.0 5.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 PSC76455.1 - 6.3e-09 35.7 6.2 8.8e-09 35.2 6.2 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 PSC76455.1 - 2.5e-08 33.6 6.0 4e-08 33.0 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC76455.1 - 1.8e-06 27.9 4.5 3e-06 27.1 4.5 1.4 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 PSC76455.1 - 3.6e-06 26.7 4.7 6.1e-06 26.0 4.7 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 PSC76455.1 - 5.2e-06 26.2 5.0 8.2e-06 25.6 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 PSC76455.1 - 9.3e-06 25.3 4.1 1.5e-05 24.7 4.1 1.2 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 PSC76455.1 - 9.8e-05 22.6 7.5 0.00035 20.8 7.5 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 PSC76455.1 - 0.00011 21.9 2.0 0.00018 21.2 2.0 1.4 1 0 0 1 1 1 1 RING-like zinc finger UBA2_C PF16195.5 PSC76455.1 - 0.00026 21.6 0.4 0.0009 19.9 0.3 1.9 2 0 0 2 2 2 1 SUMO-activating enzyme subunit 2 C-terminus Rtf2 PF04641.12 PSC76455.1 - 0.047 13.0 3.6 0.077 12.4 3.6 1.2 1 0 0 1 1 1 0 Rtf2 RING-finger zinc-ribbons_6 PF07191.12 PSC76455.1 - 0.074 13.0 4.8 0.11 12.5 4.8 1.2 1 0 0 1 1 1 0 zinc-ribbons zf-ANAPC11 PF12861.7 PSC76455.1 - 0.47 10.5 5.1 1.3 9.1 5.1 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 PSC76455.1 - 1.1 9.5 8.9 0.087 13.0 3.9 1.7 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 PSC76455.1 - 3.8 7.7 7.5 7.2 6.8 7.5 1.4 1 1 0 1 1 1 0 zinc RING finger of MSL2 ZapB PF06005.12 PSC76456.1 - 0.15 12.5 1.6 0.37 11.2 1.6 1.7 1 0 0 1 1 1 0 Cell division protein ZapB Nup84_Nup100 PF04121.13 PSC76457.1 - 2.7e-67 227.5 0.0 8.9e-66 222.5 0.0 2.1 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Nup84_Nup100 PF04121.13 PSC76458.1 - 2.8e-67 227.4 0.0 9.3e-66 222.4 0.0 2.1 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 Glyco_hydro_46 PF01374.18 PSC76459.1 - 3.4e-44 151.0 0.1 9e-44 149.6 0.1 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 46 Pectate_lyase_3 PF12708.7 PSC76459.1 - 2.1e-38 132.3 10.1 4e-14 53.0 0.1 5.1 5 0 0 5 5 5 3 Pectate lyase superfamily protein Gal_Lectin PF02140.18 PSC76459.1 - 1.5e-16 60.6 3.2 5.8e-05 23.5 0.1 3.8 3 0 0 3 3 3 3 Galactose binding lectin domain Chitin_bind_1 PF00187.19 PSC76459.1 - 4.3e-10 39.9 45.1 3.2e-07 30.7 16.3 3.8 4 0 0 4 4 4 2 Chitin recognition protein End_N_terminal PF12218.8 PSC76459.1 - 4.4e-07 29.5 7.9 0.075 12.7 0.1 3.6 3 0 0 3 3 3 3 N terminal extension of bacteriophage endosialidase Beta_helix PF13229.6 PSC76459.1 - 2.7e-05 24.1 17.8 0.11 12.3 5.2 3.6 3 0 0 3 3 3 3 Right handed beta helix region NosD PF05048.13 PSC76459.1 - 1.7 7.9 8.0 4.2 6.6 1.3 3.3 3 1 0 3 3 3 0 Periplasmic copper-binding protein (NosD) Histone PF00125.24 PSC76460.1 - 2.3e-43 147.7 1.2 4.2e-43 146.9 1.2 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Acetyltransf_3 PF13302.7 PSC76460.1 - 1.8e-20 74.0 0.0 3e-20 73.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PSC76460.1 - 1.3e-08 35.1 0.0 2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.7 PSC76460.1 - 5e-05 23.5 0.0 8.4e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 PSC76460.1 - 0.00037 20.2 0.0 0.0008 19.1 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain CENP-T_C PF15511.6 PSC76460.1 - 0.00059 19.9 0.0 0.0014 18.7 0.0 1.6 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 PSC76460.1 - 0.0014 19.0 0.0 0.0044 17.4 0.0 1.7 2 0 0 2 2 2 1 CENP-S protein FR47 PF08445.10 PSC76460.1 - 0.0074 16.2 0.0 0.017 15.1 0.0 1.6 2 0 0 2 2 2 1 FR47-like protein CBFD_NFYB_HMF PF00808.23 PSC76460.1 - 0.0087 16.3 0.0 0.027 14.8 0.0 1.8 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone GNAT_acetyltran PF12746.7 PSC76460.1 - 0.009 15.6 0.0 0.014 14.9 0.0 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase DinB_2 PF12867.7 PSC76460.1 - 0.11 13.1 0.9 3.8 8.1 0.2 2.3 2 0 0 2 2 2 0 DinB superfamily PNTB PF02233.16 PSC76461.1 - 1.3e-174 581.5 25.3 1.3e-174 581.5 25.3 2.2 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 PSC76461.1 - 1e-70 237.4 0.3 2.6e-70 236.0 0.3 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 PSC76461.1 - 1.2e-43 148.7 0.0 3.1e-43 147.3 0.0 1.8 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 PSC76461.1 - 2e-29 101.9 3.7 2e-29 101.9 3.7 3.4 3 0 0 3 3 3 1 4TM region of pyridine nucleotide transhydrogenase, mitoch Pyr_redox_2 PF07992.14 PSC76461.1 - 0.0035 16.6 0.2 0.011 15.0 0.2 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase TPP_enzyme_M PF00205.22 PSC76461.1 - 0.0048 16.6 0.6 0.029 14.1 0.5 2.5 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain 2-Hacid_dh_C PF02826.19 PSC76461.1 - 0.017 14.5 0.6 1.5 8.2 0.2 3.1 2 1 1 3 3 3 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox PF00070.27 PSC76461.1 - 0.035 14.7 1.2 0.15 12.6 0.8 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 PSC76461.1 - 0.14 12.7 0.1 0.51 10.8 0.1 1.9 2 0 0 2 2 2 0 Putative NAD(P)-binding NAD_binding_8 PF13450.6 PSC76461.1 - 0.14 12.4 3.4 0.8 10.0 1.2 3.4 3 1 0 3 3 3 0 NAD(P)-binding Rossmann-like domain EMP70 PF02990.16 PSC76462.1 - 8.5e-164 546.0 14.8 1.1e-163 545.7 14.8 1.1 1 0 0 1 1 1 1 Endomembrane protein 70 Cortexin PF11057.8 PSC76462.1 - 3.2 7.7 6.6 5.8 6.8 0.3 3.5 3 0 0 3 3 3 0 Cortexin of kidney ECH_1 PF00378.20 PSC76463.1 - 2.4e-77 259.6 0.9 3.3e-77 259.2 0.9 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 PSC76463.1 - 1.3e-34 120.2 3.7 1.1e-33 117.1 3.5 1.9 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 PSC76463.1 - 0.07 13.1 0.1 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 Peptidase family S49 DUF3235 PF11574.8 PSC76463.1 - 0.27 12.1 3.2 0.64 10.9 3.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3235) MAGE_N PF12440.8 PSC76463.1 - 0.54 11.0 3.2 1.2 9.9 3.2 1.5 1 0 0 1 1 1 0 Melanoma associated antigen family N terminal HlyIII PF03006.20 PSC76465.1 - 1e-26 94.1 11.1 1.4e-26 93.7 11.1 1.2 1 0 0 1 1 1 1 Haemolysin-III related ATP-synt_Z PF16594.5 PSC76465.1 - 0.00073 19.0 0.9 0.0041 16.6 0.9 2.3 1 0 0 1 1 1 1 Putative AtpZ or ATP-synthase-associated 5TM-5TMR_LYT PF07694.12 PSC76465.1 - 2.6 7.5 7.9 0.68 9.4 2.6 2.1 2 0 0 2 2 2 0 5TMR of 5TMR-LYT COG5 PF10392.9 PSC76466.1 - 6.7e-21 74.8 1.9 1.5e-20 73.7 1.9 1.6 1 0 0 1 1 1 1 Golgi transport complex subunit 5 HhH-GPD PF00730.25 PSC76466.1 - 1.7e-20 73.5 0.0 5.3e-20 71.9 0.0 1.9 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 PSC76466.1 - 7.7e-07 28.7 0.0 4.6e-06 26.2 0.0 2.5 1 0 0 1 1 1 1 Helix-hairpin-helix motif COG2 PF06148.11 PSC76466.1 - 0.001 19.1 0.2 0.0025 17.9 0.2 1.6 1 0 0 1 1 1 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.11 PSC76466.1 - 0.063 13.4 0.4 0.36 10.9 0.0 2.5 2 1 1 3 3 3 0 Vps51/Vps67 CLZ PF16526.5 PSC76466.1 - 0.11 12.9 0.6 4.9 7.6 0.1 3.7 2 1 1 3 3 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Vps53_N PF04100.12 PSC76466.1 - 0.42 9.5 0.9 0.66 8.9 0.9 1.2 1 0 0 1 1 1 0 Vps53-like, N-terminal DUF3989 PF13150.6 PSC76467.1 - 0.14 11.9 0.0 0.34 10.7 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) Oxidored_q2 PF00420.24 PSC76467.1 - 0.19 11.4 2.8 0.09 12.4 0.7 1.6 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L Pyr_redox_2 PF07992.14 PSC76468.1 - 1.1e-41 143.0 0.0 1.6e-41 142.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_25 PF13649.6 PSC76468.1 - 1.9e-13 51.0 0.2 5.7e-13 49.4 0.2 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC76468.1 - 6.3e-10 39.6 0.1 2.2e-09 37.9 0.1 2.0 1 0 0 1 1 1 1 Methyltransferase domain Pyr_redox PF00070.27 PSC76468.1 - 1.3e-08 35.3 0.1 4.4e-08 33.6 0.1 1.9 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Methyltransf_31 PF13847.6 PSC76468.1 - 3.4e-08 33.4 0.0 6.8e-08 32.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC76468.1 - 1.1e-07 31.9 0.1 3.3e-07 30.3 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC76468.1 - 0.00017 21.0 0.0 0.00031 20.2 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 PSC76468.1 - 0.0011 19.6 0.0 0.0041 17.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain UPF0020 PF01170.18 PSC76468.1 - 0.072 12.8 0.0 0.23 11.1 0.0 1.7 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 DUF938 PF06080.12 PSC76468.1 - 0.083 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF938) AhpC-TSA PF00578.21 PSC76469.1 - 1.4e-39 134.8 0.0 1.9e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 PSC76469.1 - 1.2e-16 60.8 0.0 1.6e-16 60.3 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 PSC76469.1 - 8.7e-12 44.7 0.1 1.9e-11 43.6 0.1 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Presenilin PF01080.17 PSC76470.1 - 1.1e-116 389.9 0.0 1.6e-116 389.4 0.0 1.1 1 0 0 1 1 1 1 Presenilin DUF4242 PF14026.6 PSC76470.1 - 1e-19 70.5 0.0 2.7e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4242) 2OG-FeII_Oxy PF03171.20 PSC76470.1 - 4e-12 46.5 0.0 9.3e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Presenilin PF01080.17 PSC76471.1 - 1.2e-116 389.8 0.0 1.7e-116 389.3 0.0 1.1 1 0 0 1 1 1 1 Presenilin DUF4242 PF14026.6 PSC76471.1 - 1.1e-19 70.4 0.0 2.8e-19 69.1 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4242) 2OG-FeII_Oxy PF03171.20 PSC76471.1 - 4.2e-12 46.4 0.0 9.7e-12 45.3 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily rve PF00665.26 PSC76472.1 - 3.7e-32 111.0 0.0 1.6e-18 67.0 0.0 2.6 2 0 0 2 2 2 2 Integrase core domain rve_3 PF13683.6 PSC76472.1 - 7e-08 32.1 0.3 0.017 14.8 0.0 2.6 2 0 0 2 2 2 2 Integrase core domain AAA_25 PF13481.6 PSC76472.1 - 0.017 14.7 2.0 2.2 7.8 0.2 3.2 2 1 0 2 2 2 0 AAA domain Stig1 PF04885.13 PSC76473.1 - 1e-08 35.8 22.0 2.2e-06 28.2 3.2 5.5 3 1 2 5 5 5 2 Stigma-specific protein, Stig1 Stig1 PF04885.13 PSC76474.1 - 1e-08 35.8 22.0 2.2e-06 28.2 3.2 5.2 3 1 1 4 4 4 2 Stigma-specific protein, Stig1 Stig1 PF04885.13 PSC76475.1 - 0.00099 19.6 11.7 0.00099 19.6 11.7 5.1 2 2 1 4 4 4 1 Stigma-specific protein, Stig1 Glyoxalase PF00903.25 PSC76476.1 - 1e-06 28.9 0.0 2.1e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 PSC76476.1 - 6e-05 23.8 0.7 0.00053 20.8 0.0 2.6 3 0 0 3 3 3 1 Glyoxalase-like domain Gly_transf_sug PF04488.15 PSC76477.1 - 1.5e-10 41.6 0.1 2.9e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Gal_Lectin PF02140.18 PSC76477.1 - 5.2e-08 33.2 0.2 0.00093 19.6 0.2 3.6 2 1 0 2 2 2 2 Galactose binding lectin domain F-box-like PF12937.7 PSC76477.1 - 0.001 18.9 0.0 0.0028 17.5 0.0 1.7 1 0 0 1 1 1 1 F-box-like Spt20 PF12090.8 PSC76477.1 - 0.19 11.3 0.7 0.28 10.7 0.7 1.2 1 0 0 1 1 1 0 Spt20 family Fasciclin PF02469.22 PSC76478.1 - 1.5e-16 60.8 1.1 6.6e-16 58.7 1.1 1.8 1 1 0 1 1 1 1 Fasciclin domain Fasciclin PF02469.22 PSC76479.1 - 2.4e-16 60.1 1.1 1e-15 58.0 1.1 1.8 1 1 0 1 1 1 1 Fasciclin domain Tubulin PF00091.25 PSC76480.1 - 5.5e-42 144.2 0.7 1e-41 143.4 0.6 1.5 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 PSC76480.1 - 1.3e-31 108.7 1.1 3.1e-31 107.5 1.1 1.7 1 0 0 1 1 1 1 FtsZ family, C-terminal domain NAD_binding_10 PF13460.6 PSC76480.1 - 0.059 13.2 0.3 0.17 11.8 0.1 1.9 2 0 0 2 2 2 0 NAD(P)H-binding Tubulin_2 PF13809.6 PSC76480.1 - 2.2 7.4 6.4 3 6.9 1.3 2.2 1 1 0 2 2 2 0 Tubulin like PIG-Y PF15159.6 PSC76481.1 - 3e-15 56.9 0.2 3.3e-15 56.7 0.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y PorA PF11271.8 PSC76481.1 - 0.049 12.9 1.6 0.051 12.9 1.6 1.2 1 0 0 1 1 1 0 Porin PorA PIG-P PF08510.12 PSC76481.1 - 0.12 12.3 0.6 0.14 12.0 0.6 1.1 1 0 0 1 1 1 0 PIG-P DUF4538 PF15061.6 PSC76481.1 - 0.37 10.6 1.0 0.64 9.8 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4538) adh_short PF00106.25 PSC76482.1 - 1.3e-41 142.2 0.1 2.4e-41 141.4 0.1 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC76482.1 - 3.9e-29 101.9 0.8 8.5e-29 100.8 0.8 1.6 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase RVT_1 PF00078.27 PSC76482.1 - 1.3e-16 60.8 0.0 3e-15 56.3 0.0 2.2 1 1 1 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) KR PF08659.10 PSC76482.1 - 3.4e-07 30.3 0.4 1e-06 28.8 0.1 1.9 2 0 0 2 2 2 1 KR domain Exo_endo_phos PF03372.23 PSC76482.1 - 0.00082 18.9 0.2 0.002 17.7 0.2 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Epimerase PF01370.21 PSC76482.1 - 0.0046 16.4 0.1 0.016 14.7 0.0 2.0 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ApbA PF02558.16 PSC76482.1 - 0.031 13.9 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA 4HBT PF03061.22 PSC76483.1 - 2e-16 60.1 2.2 4.5e-15 55.8 0.4 3.0 3 0 0 3 3 3 1 Thioesterase superfamily EamA PF00892.20 PSC76483.1 - 4.1e-16 59.4 29.7 6.6e-12 45.8 10.8 2.5 2 0 0 2 2 2 2 EamA-like transporter family 4HBT_3 PF13622.6 PSC76483.1 - 1.5e-06 28.7 3.7 1.5e-06 28.7 3.7 3.7 2 1 1 3 3 3 1 Thioesterase-like superfamily DUF4442 PF14539.6 PSC76483.1 - 6.5e-05 23.1 1.5 0.0002 21.5 1.5 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) TPT PF03151.16 PSC76483.1 - 0.099 12.0 6.9 0.093 12.1 5.4 1.8 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF1601 PF07671.11 PSC76483.1 - 0.27 11.1 3.7 41 4.1 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1601) Fasciclin PF02469.22 PSC76484.1 - 2e-17 63.6 0.2 4.7e-17 62.4 0.2 1.6 1 1 0 1 1 1 1 Fasciclin domain Acetyltransf_6 PF13480.7 PSC76485.1 - 0.18 12.0 0.2 0.18 12.0 0.2 2.4 1 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Methyltransf_28 PF02636.17 PSC76486.1 - 0.2 11.3 0.0 0.35 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Tho2 PF11262.8 PSC76487.1 - 1e-68 231.7 0.0 9e-49 166.3 0.0 2.7 3 0 0 3 3 3 2 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 PSC76487.1 - 1.4e-58 199.1 0.0 2e-36 125.9 0.0 4.1 4 1 0 4 4 4 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 PSC76487.1 - 3.3e-19 68.7 0.3 9.2e-19 67.3 0.1 1.9 2 0 0 2 2 2 1 Transcription- and export-related complex subunit SBP PF03110.14 PSC76487.1 - 5.6e-15 55.4 10.8 2.3e-14 53.5 10.8 2.1 1 0 0 1 1 1 1 SBP domain NMD3 PF04981.13 PSC76487.1 - 0.51 9.8 3.0 0.33 10.4 0.7 1.7 2 0 0 2 2 2 0 NMD3 family DZR PF12773.7 PSC76487.1 - 3.5 7.7 6.1 3.2 7.9 3.7 2.2 2 0 0 2 2 2 0 Double zinc ribbon LPP PF04728.13 PSC76487.1 - 3.6 8.0 7.8 16 6.0 0.0 4.0 3 0 0 3 3 3 0 Lipoprotein leucine-zipper ABC_tran_CTD PF16326.5 PSC76487.1 - 5.1 7.4 6.2 11 6.4 0.6 4.1 3 0 0 3 3 3 0 ABC transporter C-terminal domain MATH PF00917.26 PSC76488.1 - 0.00015 21.9 0.0 0.00042 20.4 0.0 1.7 1 1 0 1 1 1 1 MATH domain BTB PF00651.31 PSC76488.1 - 0.028 14.7 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain rve PF00665.26 PSC76489.1 - 8.5e-16 58.2 0.1 9.6e-15 54.8 0.1 2.3 1 1 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC76489.1 - 0.0064 16.2 0.0 0.018 14.8 0.0 1.7 1 0 0 1 1 1 1 Integrase core domain TPR_2 PF07719.17 PSC76490.1 - 3.3e-11 42.4 8.3 0.12 12.5 0.0 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 PSC76490.1 - 6e-09 35.4 1.0 2.2 8.7 0.0 5.5 6 0 0 6 6 4 3 Tetratricopeptide repeat TPR_16 PF13432.6 PSC76490.1 - 6.7e-08 33.1 4.0 2.2e-06 28.2 3.5 5.1 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 PSC76490.1 - 2.1e-07 31.2 30.7 0.11 13.4 0.2 7.0 7 2 2 9 9 8 4 Tetratricopeptide repeat TPR_12 PF13424.6 PSC76490.1 - 4.7e-07 30.0 16.7 0.028 14.7 2.1 5.6 5 2 0 5 5 5 3 Tetratricopeptide repeat TPR_15 PF13429.6 PSC76490.1 - 8.5e-07 28.5 2.6 0.032 13.4 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 PSC76490.1 - 1.7e-06 27.6 5.8 0.4 10.6 0.1 4.7 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 PSC76490.1 - 4e-06 26.5 6.8 0.00021 21.1 0.3 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 PSC76490.1 - 1.2e-05 25.7 3.9 0.0027 18.2 0.1 4.4 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 PSC76490.1 - 1.4e-05 25.2 0.3 2.5 8.7 0.0 4.8 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_11 PF13414.6 PSC76490.1 - 7.5e-05 22.3 5.1 3 7.6 0.0 5.0 4 1 1 5 5 5 2 TPR repeat ANAPC3 PF12895.7 PSC76490.1 - 0.00098 19.3 2.7 0.059 13.6 0.0 3.4 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 Wzy_C_2 PF11846.8 PSC76490.1 - 0.0011 18.9 4.8 0.15 12.0 0.7 2.5 2 0 0 2 2 2 2 Virulence factor membrane-bound polymerase, C-terminal TPR_6 PF13174.6 PSC76490.1 - 0.0076 16.8 8.5 45 5.0 0.0 6.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_10 PF13374.6 PSC76490.1 - 0.017 15.0 0.4 0.017 15.0 0.4 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_9 PF13371.6 PSC76490.1 - 0.081 13.1 10.6 7.1 6.9 0.1 4.2 3 1 0 3 3 3 0 Tetratricopeptide repeat MC1 PF05854.11 PSC76490.1 - 0.44 10.9 3.5 1.5 9.2 3.5 1.9 1 0 0 1 1 1 0 Non-histone chromosomal protein MC1 PGA2 PF07543.12 PSC76490.1 - 8.6 6.3 8.2 2 8.4 3.9 2.1 2 0 0 2 2 2 0 Protein trafficking PGA2 Kazal_1 PF00050.21 PSC76491.1 - 5.3e-21 74.4 24.5 4.2e-06 26.7 2.2 4.4 3 1 1 4 4 4 4 Kazal-type serine protease inhibitor domain Kazal_2 PF07648.15 PSC76491.1 - 2.1e-11 43.7 36.7 0.00043 20.4 1.2 4.7 4 0 0 4 4 4 4 Kazal-type serine protease inhibitor domain DnaJ_C PF01556.18 PSC76492.1 - 6e-22 78.3 0.0 9.8e-22 77.6 0.0 1.3 1 1 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 PSC76492.1 - 1.8e-20 72.8 0.0 2.7e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 PSC76492.1 - 0.0013 19.0 21.1 0.003 17.9 21.1 1.6 1 0 0 1 1 1 1 DnaJ central domain TPR_2 PF07719.17 PSC76493.1 - 1.1e-09 37.7 9.6 0.021 14.9 0.3 5.2 5 1 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 PSC76493.1 - 2.5e-09 36.6 0.8 0.064 13.1 0.0 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 PSC76493.1 - 9.6e-07 29.0 2.6 9.6e-07 29.0 2.6 3.9 3 1 1 4 4 3 1 Tetratricopeptide repeat 60KD_IMP PF02096.20 PSC76493.1 - 1.4e-06 28.3 2.0 1.4e-06 28.3 2.0 2.8 2 1 0 2 2 2 1 60Kd inner membrane protein TPR_8 PF13181.6 PSC76493.1 - 2.1e-05 24.3 0.0 0.84 10.0 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.6 PSC76493.1 - 8.9e-05 22.9 9.6 0.037 14.5 1.4 3.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 PSC76493.1 - 0.00056 19.7 5.5 4.9 7.4 0.3 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 PSC76493.1 - 0.00077 20.1 11.9 0.0032 18.1 4.1 8.1 7 1 2 9 9 5 3 Tetratricopeptide repeat TPR_14 PF13428.6 PSC76493.1 - 0.0012 19.5 6.4 0.014 16.2 0.8 6.6 4 1 3 7 7 6 4 Tetratricopeptide repeat TPR_11 PF13414.6 PSC76493.1 - 0.0021 17.7 1.6 0.89 9.3 0.1 3.4 3 0 0 3 3 3 1 TPR repeat TPR_17 PF13431.6 PSC76493.1 - 0.013 15.8 0.7 5.2 7.7 0.0 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 PSC76493.1 - 0.03 15.0 15.3 6.3 7.7 0.1 5.5 5 0 0 5 5 4 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PSC76493.1 - 0.15 12.3 6.0 2.8 8.3 0.1 2.9 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 Suf PF05843.14 PSC76493.1 - 4.6 7.1 9.0 2.1 8.2 3.8 2.1 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DSPc PF00782.20 PSC76494.1 - 1.9e-29 102.2 0.0 2.2e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PSC76494.1 - 0.027 14.0 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 PSC76495.1 - 4.9e-29 100.8 0.0 6.2e-29 100.5 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 PSC76495.1 - 0.041 13.4 0.0 0.062 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase TB2_DP1_HVA22 PF03134.19 PSC76496.1 - 2.1e-19 69.2 0.1 3.1e-19 68.7 0.1 1.2 1 0 0 1 1 1 1 TB2/DP1, HVA22 family Macoilin PF09726.9 PSC76497.1 - 0.0061 15.2 0.0 0.0061 15.2 0.0 1.8 2 0 0 2 2 2 1 Macoilin family Lebercilin PF15619.6 PSC76497.1 - 0.43 10.2 10.0 0.094 12.4 5.5 2.2 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF3584 PF12128.8 PSC76497.1 - 0.52 7.8 7.3 0.82 7.1 7.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) LCE6A PF15858.5 PSC76497.1 - 2.1 9.1 13.4 0.028 15.2 4.6 2.5 2 0 0 2 2 2 0 Late cornified envelope protein 6A family GAS PF13851.6 PSC76497.1 - 3.1 7.1 7.4 5.8 6.2 1.1 2.4 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Actin PF00022.19 PSC76499.1 - 1.9e-53 181.6 0.0 2.3e-53 181.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 PSC76499.1 - 5.5e-06 25.4 0.0 5.9e-06 25.3 0.0 1.2 1 0 0 1 1 1 1 MreB/Mbl protein Actin PF00022.19 PSC76500.1 - 4.8e-134 447.0 0.0 5.4e-134 446.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 PSC76500.1 - 1e-09 37.7 0.0 3.6e-06 26.0 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Actin PF00022.19 PSC76501.1 - 1.8e-73 247.5 0.0 2.1e-73 247.3 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 PSC76501.1 - 0.11 11.3 0.0 0.15 10.8 0.0 1.2 1 0 0 1 1 1 0 MreB/Mbl protein F-box-like PF12937.7 PSC76502.1 - 5.7e-05 22.9 0.4 0.00017 21.4 0.4 1.9 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 PSC76502.1 - 6.3e-05 22.6 4.6 0.014 15.2 0.6 3.4 3 0 0 3 3 3 2 Leucine rich repeat LRR_8 PF13855.6 PSC76503.1 - 3.8e-05 23.4 4.6 0.011 15.4 0.6 3.5 3 0 0 3 3 3 2 Leucine rich repeat F-box-like PF12937.7 PSC76503.1 - 5.3e-05 23.0 0.4 0.00014 21.7 0.4 1.8 1 0 0 1 1 1 1 F-box-like Methyltransf_16 PF10294.9 PSC76504.1 - 7.6e-23 81.1 0.0 1.1e-22 80.6 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 PSC76504.1 - 0.035 13.7 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain Acyltransferase PF01553.21 PSC76505.1 - 2.2e-08 33.8 0.0 3.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase YccV-like PF08755.11 PSC76506.1 - 1.1e-17 64.3 0.0 1.8e-17 63.6 0.0 1.3 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like UVR PF02151.19 PSC76506.1 - 8.2e-06 25.4 1.0 8.2e-06 25.4 1.0 2.3 2 0 0 2 2 2 1 UvrB/uvrC motif FrhB_FdhB_C PF04432.13 PSC76507.1 - 1.3e-33 116.1 0.0 3e-33 114.8 0.0 1.6 2 0 0 2 2 2 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus FrhB_FdhB_N PF04422.13 PSC76507.1 - 2.1e-27 95.1 0.0 3.8e-27 94.2 0.0 1.5 1 0 0 1 1 1 1 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term Cytochrome_CBB3 PF13442.6 PSC76507.1 - 2e-17 63.3 0.1 2.1e-16 60.0 0.0 2.5 2 0 0 2 2 2 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 PSC76507.1 - 2e-06 28.8 0.2 9.8e-06 26.6 0.2 2.2 1 1 0 1 1 1 1 Cytochrome c Cytochrom_C550 PF14495.6 PSC76507.1 - 5.3e-05 23.0 0.0 0.00096 18.9 0.0 2.3 2 0 0 2 2 2 1 Cytochrome c-550 domain Hydrolase_4 PF12146.8 PSC76508.1 - 1.7e-19 70.0 0.1 2.5e-13 49.9 0.0 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 PSC76508.1 - 5.3e-12 45.9 4.7 9.7e-10 38.5 0.1 2.8 2 1 0 3 3 3 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.18 PSC76508.1 - 1.8e-10 40.8 5.2 2e-08 34.2 0.0 3.4 3 1 0 4 4 4 2 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.21 PSC76508.1 - 1.6e-06 27.8 0.0 7.9e-06 25.5 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family UIM PF02809.20 PSC76508.1 - 1.9e-05 24.3 19.8 0.013 15.4 4.1 3.0 2 0 0 2 2 2 2 Ubiquitin interaction motif FSH1 PF03959.13 PSC76508.1 - 4.5e-05 23.2 0.0 0.00012 21.9 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) RAP80_UIM PF18282.1 PSC76508.1 - 0.031 14.0 2.6 0.96 9.3 1.1 2.4 2 0 0 2 2 2 0 RAP80 N-terminal ubiquitin interaction motif AXE1 PF05448.12 PSC76508.1 - 0.08 11.6 0.0 1.1 7.9 0.0 2.4 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) BAAT_C PF08840.11 PSC76508.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF393 PF04134.12 PSC76509.1 - 6.9e-18 66.0 0.1 8.3e-18 65.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF393 Pentapeptide_2 PF01469.18 PSC76510.1 - 5.1e-06 26.3 22.4 9.1e-06 25.5 22.4 1.4 1 0 0 1 1 1 1 Pentapeptide repeats (8 copies) MAD PF05557.13 PSC76510.1 - 0.014 13.8 4.6 0.018 13.5 4.6 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein ADIP PF11559.8 PSC76510.1 - 2.9 8.0 4.6 5.1 7.2 4.6 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding PK PF00224.21 PSC76511.1 - 5.9e-68 229.3 0.0 8.7e-68 228.7 0.0 1.2 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 PSC76511.1 - 2.1e-19 69.9 0.7 6.1e-19 68.4 0.1 2.1 2 0 0 2 2 2 1 Pyruvate kinase, alpha/beta domain zf-MYND PF01753.18 PSC76511.1 - 2.3e-08 34.0 16.0 7.1e-05 22.8 5.4 2.9 2 0 0 2 2 2 2 MYND finger DUF442 PF04273.13 PSC76511.1 - 0.097 12.8 0.1 5.8 7.0 0.0 3.0 2 0 0 2 2 2 0 Putative phosphatase (DUF442) FAD_binding_1 PF00667.20 PSC76512.1 - 8.1e-27 94.2 0.0 5.7e-14 52.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain Flavodoxin_1 PF00258.25 PSC76512.1 - 8.3e-20 71.5 0.0 2.9e-19 69.7 0.0 2.0 1 1 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 PSC76512.1 - 2.6e-16 60.2 0.0 4.4e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain EF-hand_1 PF00036.32 PSC76513.1 - 1.2e-30 102.7 7.6 9.1e-10 37.4 0.7 3.2 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 PSC76513.1 - 7.2e-29 99.4 5.8 2.3e-16 59.4 0.9 3.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_7 PF13499.6 PSC76513.1 - 3.7e-28 97.8 1.9 5e-19 68.5 1.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 PSC76513.1 - 9.7e-22 75.0 5.4 2.8e-09 36.2 0.1 3.3 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 PSC76513.1 - 7.2e-19 66.4 5.2 1.5e-06 27.5 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_9 PF14658.6 PSC76513.1 - 4.9e-10 39.6 0.4 0.00099 19.4 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_4 PF12763.7 PSC76513.1 - 4.7e-07 29.7 1.1 0.00032 20.6 0.1 2.1 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 PSC76513.1 - 4.6e-05 23.7 0.1 0.0012 19.2 0.1 2.0 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EFhand_Ca_insen PF08726.10 PSC76513.1 - 6.3e-05 23.0 0.3 0.00017 21.6 0.2 1.8 2 1 0 2 2 2 1 Ca2+ insensitive EF hand UPF0154 PF03672.13 PSC76513.1 - 0.00014 21.9 0.1 0.57 10.3 0.0 2.8 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 PSC76513.1 - 0.00047 21.0 0.0 0.0027 18.6 0.0 1.8 1 1 1 2 2 2 1 EF-hand domain DUF1103 PF06513.11 PSC76513.1 - 0.00082 19.0 0.9 0.00099 18.8 0.9 1.1 1 0 0 1 1 1 1 Repeat of unknown function (DUF1103) TerB PF05099.13 PSC76513.1 - 0.013 15.5 0.7 0.77 9.7 0.1 2.1 1 1 1 2 2 2 0 Tellurite resistance protein TerB SurA_N_2 PF13623.6 PSC76513.1 - 0.015 15.2 0.7 0.09 12.6 0.2 2.0 1 1 1 2 2 2 0 SurA N-terminal domain dCache_2 PF08269.11 PSC76513.1 - 0.023 13.9 0.0 0.2 10.8 0.0 2.0 1 1 1 2 2 2 0 Cache domain Herpes_UL36 PF03586.13 PSC76513.1 - 0.038 13.3 0.1 5.5 6.2 0.0 2.0 1 1 1 2 2 2 0 Herpesvirus UL36 tegument protein Dockerin_1 PF00404.18 PSC76513.1 - 0.072 13.3 4.3 0.28 11.4 0.7 2.6 1 1 1 2 2 2 0 Dockerin type I domain DUF3349 PF11829.8 PSC76513.1 - 0.096 13.5 0.3 4.8 8.0 0.0 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3349) RNA_pol_Rpb4 PF03874.16 PSC76513.1 - 0.1 12.9 0.4 0.73 10.2 0.1 2.1 2 1 0 2 2 2 0 RNA polymerase Rpb4 DUF5132 PF17195.4 PSC76513.1 - 0.42 10.8 2.2 16 5.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF5132) Mpp10 PF04006.12 PSC76514.1 - 2.6e-113 379.6 43.8 2.6e-113 379.6 43.8 2.9 2 1 0 2 2 2 1 Mpp10 protein Rubis-subs-bind PF09273.11 PSC76514.1 - 4.6e-21 75.8 2.8 4.6e-21 75.8 2.8 2.8 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding RRM_1 PF00076.22 PSC76514.1 - 7.6e-13 48.1 0.0 4.8e-10 39.1 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 PSC76515.1 - 2.6e-19 69.8 0.1 8.8e-19 68.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.8 PSC76515.1 - 0.00025 21.0 0.0 0.00046 20.2 0.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CREPT PF16566.5 PSC76515.1 - 0.0036 17.5 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour DHR10 PF18595.1 PSC76515.1 - 0.022 14.8 6.7 0.067 13.2 6.7 1.8 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Spc7 PF08317.11 PSC76515.1 - 0.086 11.7 1.8 0.22 10.4 0.8 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.12 PSC76515.1 - 0.51 11.0 7.6 0.21 12.2 3.6 2.6 2 0 0 2 2 2 0 SlyX HIP1_clath_bdg PF16515.5 PSC76515.1 - 0.52 11.0 7.2 0.16 12.6 1.7 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CTD_bind PF04818.13 PSC76516.1 - 2.6e-19 69.8 0.1 8.8e-19 68.1 0.0 1.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. CTK3 PF12243.8 PSC76516.1 - 0.00025 21.0 0.0 0.00046 20.2 0.0 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CREPT PF16566.5 PSC76516.1 - 0.0036 17.5 0.0 0.01 16.0 0.0 1.7 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour DHR10 PF18595.1 PSC76516.1 - 0.022 14.8 6.7 0.067 13.2 6.7 1.8 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain Spc7 PF08317.11 PSC76516.1 - 0.086 11.7 1.8 0.22 10.4 0.8 1.9 2 0 0 2 2 2 0 Spc7 kinetochore protein SlyX PF04102.12 PSC76516.1 - 0.51 11.0 7.6 0.21 12.2 3.6 2.6 2 0 0 2 2 2 0 SlyX HIP1_clath_bdg PF16515.5 PSC76516.1 - 0.52 11.0 7.2 0.16 12.6 1.7 2.3 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 NDK PF00334.19 PSC76518.1 - 8e-52 174.8 0.0 8.8e-52 174.7 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase WD40 PF00400.32 PSC76520.1 - 9.2e-12 45.3 12.7 0.00017 22.3 0.1 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC76520.1 - 1.6e-09 38.0 0.0 1.6 9.1 0.0 4.5 5 0 0 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PSC76520.1 - 1.8e-07 30.4 0.0 0.045 12.7 0.0 3.9 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 PSC76520.1 - 0.13 12.3 0.1 70 3.5 0.0 3.8 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat WD40 PF00400.32 PSC76521.1 - 1.6e-11 44.6 5.3 9.5e-05 23.1 0.1 5.6 6 1 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC76521.1 - 2.4e-10 40.6 0.0 0.87 9.9 0.0 4.3 4 0 0 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 PSC76521.1 - 1.8e-08 33.7 0.0 0.025 13.5 0.0 4.0 3 1 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 PSC76521.1 - 0.026 14.5 0.1 42 4.2 0.0 4.0 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat Polysacc_deac_1 PF01522.21 PSC76522.1 - 1.6e-07 31.2 0.0 4.4e-07 29.8 0.0 1.7 2 1 0 2 2 2 1 Polysaccharide deacetylase SKN1 PF03935.15 PSC76523.1 - 1e-85 288.1 7.6 3e-85 286.5 7.6 1.6 1 1 0 1 1 1 1 Beta-glucan synthesis-associated protein (SKN1) Glyco_hydro_16 PF00722.21 PSC76523.1 - 1e-07 31.6 0.3 0.00073 19.1 0.1 2.3 2 0 0 2 2 2 2 Glycosyl hydrolases family 16 Lipase_GDSL_2 PF13472.6 PSC76523.1 - 2.6e-06 27.9 0.3 5.2e-05 23.7 0.3 2.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Vps62 PF06101.11 PSC76524.1 - 1.3e-17 63.3 0.0 2.8e-17 62.2 0.0 1.4 2 0 0 2 2 2 1 Vacuolar protein sorting-associated protein 62 Cmc1 PF08583.10 PSC76524.1 - 0.0026 17.7 1.2 0.0056 16.7 1.2 1.5 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Polyketide_cyc PF03364.20 PSC76525.1 - 4.8e-35 120.6 0.1 3.2e-17 62.9 0.1 2.6 2 0 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport Polyketide_cyc2 PF10604.9 PSC76525.1 - 3.8e-15 56.4 2.7 1.9e-06 28.2 0.8 3.2 2 1 0 2 2 2 2 Polyketide cyclase / dehydrase and lipid transport COXG PF06240.13 PSC76525.1 - 5.5e-06 26.2 0.0 0.013 15.2 0.0 2.5 2 0 0 2 2 2 2 Carbon monoxide dehydrogenase subunit G (CoxG) AHSA1 PF08327.11 PSC76525.1 - 0.029 14.6 0.1 2.6 8.3 0.0 2.5 2 0 0 2 2 2 0 Activator of Hsp90 ATPase homolog 1-like protein CDK2AP PF09806.9 PSC76525.1 - 0.03 14.4 0.2 0.03 14.4 0.2 4.6 5 0 0 5 5 5 0 Cyclin-dependent kinase 2-associated protein YdaS_antitoxin PF15943.5 PSC76525.1 - 0.03 14.2 0.1 8.4 6.3 0.0 2.7 2 0 0 2 2 2 0 Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT DUF4407 PF14362.6 PSC76525.1 - 5.4 6.3 12.5 14 4.9 12.5 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) MCM PF00493.23 PSC76526.1 - 1.4e-98 328.5 0.4 2.2e-98 327.8 0.4 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 PSC76526.1 - 4.6e-38 129.9 0.3 9.5e-38 128.9 0.3 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 PSC76526.1 - 7.6e-24 84.0 2.5 7.6e-24 84.0 2.5 1.8 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 PSC76526.1 - 1.3e-18 67.5 0.1 3e-18 66.3 0.1 1.7 1 0 0 1 1 1 1 MCM N-terminal domain MCM6_C PF18263.1 PSC76526.1 - 1.1e-17 64.2 0.9 1.1e-17 64.2 0.9 1.9 2 0 0 2 2 2 1 MCM6 C-terminal winged-helix domain Mg_chelatase PF01078.21 PSC76526.1 - 3.4e-07 29.8 0.0 7.4e-06 25.5 0.0 2.3 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 PSC76526.1 - 1.4e-05 24.9 0.2 0.00011 22.1 0.0 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 PSC76526.1 - 0.001 19.1 0.0 0.0024 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 PSC76526.1 - 0.011 15.5 0.0 0.023 14.4 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase_C PF13335.6 PSC76526.1 - 0.11 13.2 0.6 0.34 11.6 0.6 1.9 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI C-terminal dCMP_cyt_deam_1 PF00383.23 PSC76527.1 - 6.2e-20 71.0 0.2 9.6e-20 70.4 0.2 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 PSC76527.1 - 1.8e-16 60.1 0.0 2.5e-16 59.7 0.0 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Citrate_bind PF16114.5 PSC76528.1 - 1.3e-78 262.6 0.1 3.7e-78 261.1 0.1 1.6 2 0 0 2 2 2 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 PSC76528.1 - 2.7e-14 53.2 0.0 6.1e-14 52.1 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain Citrate_bind PF16114.5 PSC76529.1 - 1.3e-78 262.6 0.1 3.7e-78 261.1 0.1 1.6 2 0 0 2 2 2 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 PSC76529.1 - 2.7e-14 53.2 0.0 6.1e-14 52.1 0.0 1.6 2 0 0 2 2 2 1 ATP-grasp domain Coq4 PF05019.13 PSC76530.1 - 2.3e-78 262.6 0.0 2.8e-78 262.2 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 PP28 PF10252.9 PSC76530.1 - 3.7e-05 24.1 7.2 3.7e-05 24.1 7.2 1.9 2 0 0 2 2 2 1 Casein kinase substrate phosphoprotein PP28 TerB_C PF15615.6 PSC76531.1 - 3.2 8.0 10.1 1.3 9.3 0.3 4.2 3 1 0 3 3 3 0 TerB-C domain Fibrillarin PF01269.17 PSC76532.1 - 4.2e-110 366.2 0.0 4.9e-110 366.0 0.0 1.0 1 0 0 1 1 1 1 Fibrillarin GCD14 PF08704.10 PSC76532.1 - 8.7e-05 22.3 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit FtsJ PF01728.19 PSC76532.1 - 0.0065 16.6 0.1 0.013 15.6 0.1 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase PCMT PF01135.19 PSC76532.1 - 0.0091 15.8 0.1 0.017 14.9 0.1 1.4 1 1 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltr_RsmB-F PF01189.17 PSC76532.1 - 0.058 13.0 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F SIR2 PF02146.17 PSC76533.1 - 2.4e-51 174.2 0.0 3e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Sir2 family LacAB_rpiB PF02502.18 PSC76533.1 - 0.21 11.6 0.1 0.4 10.7 0.1 1.3 1 0 0 1 1 1 0 Ribose/Galactose Isomerase Resolvase PF00239.21 PSC76535.1 - 1.3e-07 31.8 0.2 1.8e-06 28.1 0.0 2.7 3 0 0 3 3 3 1 Resolvase, N terminal domain Ribosomal_L33 PF00471.20 PSC76536.1 - 2e-10 40.9 0.0 3.9e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L33 Mrpl_C PF18502.1 PSC76536.1 - 1.2 9.4 4.5 3 8.2 3.8 2.0 1 1 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain DUF1664 PF07889.12 PSC76536.1 - 4.6 7.3 11.7 16 5.5 5.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Ank_2 PF12796.7 PSC76537.1 - 3.1e-53 178.3 3.7 3.7e-12 46.7 0.0 6.0 2 2 4 6 6 6 6 Ankyrin repeats (3 copies) Ank_3 PF13606.6 PSC76537.1 - 1.6e-42 138.6 7.7 7.8e-05 22.8 0.0 10.4 11 0 0 11 11 11 9 Ankyrin repeat Ank_5 PF13857.6 PSC76537.1 - 6e-40 134.8 14.5 2.1e-08 34.3 0.0 7.6 4 3 4 8 8 8 8 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC76537.1 - 6.2e-40 135.1 5.7 7.7e-10 39.1 0.0 6.6 4 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 PSC76537.1 - 2e-39 132.3 16.1 7.6e-05 23.0 0.0 9.6 10 0 0 10 10 10 9 Ankyrin repeat HD_4 PF13328.6 PSC76538.1 - 5.2e-34 117.3 0.3 5.2e-34 117.3 0.3 1.9 2 0 0 2 2 2 1 HD domain RelA_SpoT PF04607.17 PSC76538.1 - 1.1e-29 103.1 0.0 1.7e-29 102.4 0.0 1.3 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins Ank_2 PF12796.7 PSC76538.1 - 3.1e-20 72.5 0.5 7.1e-13 49.0 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) MFS_1 PF07690.16 PSC76538.1 - 7.5e-16 58.0 22.8 1.5e-15 57.0 22.8 1.5 1 0 0 1 1 1 1 Major Facilitator Superfamily Ank_3 PF13606.6 PSC76538.1 - 2.5e-12 45.8 1.0 0.057 14.0 0.0 5.9 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 PSC76538.1 - 2.5e-11 43.9 4.9 4.4e-05 24.0 1.0 4.7 4 1 2 6 6 6 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 PSC76538.1 - 2.9e-11 43.4 4.9 6.9e-05 23.1 0.1 4.5 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Sugar_tr PF00083.24 PSC76538.1 - 1.5e-10 40.5 0.9 2.9e-10 39.6 0.9 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter Ank PF00023.30 PSC76538.1 - 3.4e-07 30.4 14.1 0.099 13.1 0.0 5.9 6 0 0 6 6 6 3 Ankyrin repeat HD PF01966.22 PSC76538.1 - 0.00088 19.5 0.0 0.0074 16.5 0.0 2.4 1 1 0 1 1 1 1 HD domain UNC-93 PF05978.16 PSC76538.1 - 2.4 7.9 5.9 0.97 9.1 2.9 1.9 2 0 0 2 2 2 0 Ion channel regulatory protein UNC-93 F-box PF00646.33 PSC76539.1 - 0.051 13.5 0.0 0.1 12.5 0.0 1.4 1 0 0 1 1 1 0 F-box domain TPR_2 PF07719.17 PSC76540.1 - 7.6e-20 69.4 34.9 0.002 18.1 0.8 10.2 11 0 0 11 11 11 6 Tetratricopeptide repeat TPR_14 PF13428.6 PSC76540.1 - 8.6e-18 63.5 42.6 0.00067 20.3 2.2 9.8 4 3 7 11 11 9 5 Tetratricopeptide repeat TPR_16 PF13432.6 PSC76540.1 - 7.7e-14 52.1 39.3 2.2e-05 25.0 4.5 6.9 6 1 1 7 7 6 5 Tetratricopeptide repeat TPR_19 PF14559.6 PSC76540.1 - 3.1e-11 43.6 16.9 0.0011 19.4 1.8 5.8 3 2 4 7 7 7 6 Tetratricopeptide repeat TPR_12 PF13424.6 PSC76540.1 - 2.3e-08 34.2 25.4 0.018 15.3 0.1 6.9 6 2 0 6 6 6 3 Tetratricopeptide repeat TPR_1 PF00515.28 PSC76540.1 - 3.1e-08 33.1 17.9 0.013 15.3 0.1 8.5 10 0 0 10 10 10 2 Tetratricopeptide repeat TPR_8 PF13181.6 PSC76540.1 - 1e-07 31.6 12.0 0.052 13.8 0.0 7.9 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_17 PF13431.6 PSC76540.1 - 2.6e-07 30.5 9.1 0.087 13.2 0.0 6.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.6 PSC76540.1 - 1.3e-06 28.0 12.2 0.55 10.0 0.3 6.9 6 1 1 7 7 7 2 TPR repeat TPR_7 PF13176.6 PSC76540.1 - 0.00014 21.7 15.9 0.0046 16.9 0.4 6.2 7 0 0 7 7 7 2 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 PSC76540.1 - 0.00018 21.5 15.6 0.57 10.2 0.1 6.6 6 3 1 7 7 6 1 Mad3/BUB1 homology region 1 TPR_15 PF13429.6 PSC76540.1 - 0.00059 19.1 24.9 0.17 11.1 2.1 4.6 1 1 3 4 4 4 3 Tetratricopeptide repeat PPR PF01535.20 PSC76540.1 - 0.00064 19.8 1.5 3.9 7.9 0.0 5.7 7 0 0 7 7 6 1 PPR repeat TPR_6 PF13174.6 PSC76540.1 - 0.00071 20.1 23.5 7.2 7.5 0.1 8.3 9 1 0 9 9 8 0 Tetratricopeptide repeat ANAPC3 PF12895.7 PSC76540.1 - 0.001 19.2 8.1 1.1 9.5 0.1 3.9 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_3 PF07720.12 PSC76540.1 - 0.0041 17.1 1.4 0.18 11.8 0.1 3.4 2 0 0 2 2 2 1 Tetratricopeptide repeat Suf PF05843.14 PSC76540.1 - 0.0044 17.0 6.3 2 8.3 0.0 3.0 3 0 0 3 3 3 1 Suppressor of forked protein (Suf) TPR_10 PF13374.6 PSC76540.1 - 0.013 15.4 0.1 0.013 15.4 0.1 6.2 8 0 0 8 8 7 0 Tetratricopeptide repeat TRAPPC9-Trs120 PF08626.11 PSC76540.1 - 0.016 12.6 0.8 0.022 12.2 0.8 1.1 1 0 0 1 1 1 0 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Alkyl_sulf_dimr PF14863.6 PSC76540.1 - 0.051 14.0 1.1 0.49 10.9 0.2 2.7 2 1 0 2 2 2 0 Alkyl sulfatase dimerisation TFIIA PF03153.13 PSC76540.1 - 0.051 13.6 9.7 0.07 13.1 9.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit HrpB1_HrpK PF09613.10 PSC76540.1 - 0.062 12.9 1.9 2.2 7.9 0.1 3.2 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) DUF2722 PF10846.8 PSC76540.1 - 0.12 11.3 5.8 0.16 10.9 5.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TPR_9 PF13371.6 PSC76540.1 - 0.46 10.7 28.3 8.9 6.5 0.7 6.5 4 1 2 6 6 6 0 Tetratricopeptide repeat Spt20 PF12090.8 PSC76540.1 - 4.5 6.8 14.5 7 6.2 14.5 1.1 1 0 0 1 1 1 0 Spt20 family MMgT PF10270.9 PSC76541.1 - 0.01 16.2 0.0 0.012 16.0 0.0 1.1 1 0 0 1 1 1 0 Membrane magnesium transporter RhodobacterPufX PF11511.8 PSC76541.1 - 0.13 11.9 0.1 0.29 10.8 0.1 1.5 1 0 0 1 1 1 0 Intrinsic membrane protein PufX PSI_PSAK PF01241.18 PSC76542.1 - 6.6e-21 74.1 1.0 8.7e-21 73.7 1.0 1.2 1 0 0 1 1 1 1 Photosystem I psaG / psaK PseudoU_synth_2 PF00849.22 PSC76543.1 - 1.5e-18 67.4 0.0 5.1e-18 65.7 0.0 1.9 2 1 0 2 2 2 1 RNA pseudouridylate synthase Mito_carr PF00153.27 PSC76543.1 - 2.3e-14 53.1 14.0 0.0001 22.2 0.1 3.9 4 0 0 4 4 4 3 Mitochondrial carrier protein S4 PF01479.25 PSC76543.1 - 0.003 17.2 0.0 0.0067 16.1 0.0 1.6 1 0 0 1 1 1 1 S4 domain Kinesin PF00225.23 PSC76545.1 - 5e-84 282.1 0.1 1.1e-83 281.0 0.0 1.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 PSC76545.1 - 2.6e-13 50.2 0.0 5e-13 49.2 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Cnn_1N PF07989.11 PSC76545.1 - 3.6 7.8 0.0 3.6 7.8 0.0 3.5 3 0 0 3 3 3 0 Centrosomin N-terminal motif 1 Pro_isomerase PF00160.21 PSC76546.1 - 1.5e-12 48.1 0.0 4.3e-12 46.6 0.0 1.7 1 1 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PsbQ PF05757.11 PSC76546.1 - 0.022 14.5 0.6 0.037 13.8 0.6 1.4 1 0 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) RWP-RK PF02042.15 PSC76547.1 - 1.4e-11 44.1 0.0 3.4e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 RWP-RK domain Beta_helix PF13229.6 PSC76548.1 - 7.7e-13 48.6 0.0 1.2e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Right handed beta helix region Presenilin PF01080.17 PSC76548.1 - 0.00093 18.1 0.1 0.0015 17.4 0.1 1.3 1 0 0 1 1 1 1 Presenilin DUF1565 PF07602.11 PSC76548.1 - 0.0041 16.5 0.0 0.53 9.6 0.0 3.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1565) DDHD PF02862.17 PSC76548.1 - 0.0065 16.7 0.1 0.0099 16.1 0.1 1.4 1 0 0 1 1 1 1 DDHD domain EPL1 PF10513.9 PSC76548.1 - 0.058 13.8 5.2 0.091 13.1 5.2 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like Neur_chan_memb PF02932.16 PSC76548.1 - 0.28 11.2 1.6 0.42 10.6 1.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SpoIIP PF07454.11 PSC76548.1 - 0.3 10.5 5.6 0.47 9.9 5.6 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) MDM10 PF12519.8 PSC76548.1 - 0.32 9.8 1.8 0.5 9.2 1.8 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 Rrn6 PF10214.9 PSC76548.1 - 1.4 7.4 10.9 2.1 6.8 10.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Connexin PF00029.19 PSC76548.1 - 1.7 8.3 9.0 2.8 7.6 9.0 1.2 1 0 0 1 1 1 0 Connexin GREB1 PF15782.5 PSC76548.1 - 2.6 5.1 5.1 3.5 4.6 5.1 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Afi1 PF07792.12 PSC76548.1 - 3.6 8.1 7.9 30 5.1 8.8 1.8 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF4834 PF16118.5 PSC76548.1 - 4.1 8.4 12.1 10 7.2 12.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) MCM_bind PF09739.9 PSC76548.1 - 4.5 5.6 8.4 6.3 5.1 8.4 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Paf1 PF03985.13 PSC76548.1 - 4.6 6.1 13.3 6.1 5.7 13.3 1.1 1 0 0 1 1 1 0 Paf1 DUF4638 PF15472.6 PSC76548.1 - 5.5 6.6 11.7 9 5.9 11.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) Med15 PF09606.10 PSC76548.1 - 9.3 4.8 22.8 1.4 7.5 13.6 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Exostosin PF03016.15 PSC76549.1 - 1.4e-51 175.5 0.1 1.9e-51 175.1 0.1 1.1 1 0 0 1 1 1 1 Exostosin family EGF_2 PF07974.13 PSC76549.1 - 4.1e-07 30.3 53.6 0.00022 21.5 5.7 4.5 4 0 0 4 4 4 3 EGF-like domain Pterin_4a PF01329.19 PSC76549.1 - 0.19 11.9 0.1 0.47 10.7 0.1 1.6 1 0 0 1 1 1 0 Pterin 4 alpha carbinolamine dehydratase EGF_Tenascin PF18720.1 PSC76549.1 - 5.3 7.2 14.1 0.1 12.7 4.0 3.2 3 0 0 3 3 3 0 Tenascin EGF domain Aminotran_4 PF01063.19 PSC76550.1 - 1.1e-21 77.7 0.0 4.1e-20 72.6 0.0 2.1 1 1 0 1 1 1 1 Amino-transferase class IV Ank_2 PF12796.7 PSC76551.1 - 6.4e-126 411.2 99.0 3.9e-15 56.2 2.0 16.0 8 3 12 20 20 20 19 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC76551.1 - 4.7e-87 284.9 77.5 1.5e-10 41.1 0.1 25.1 12 7 15 27 27 27 23 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC76551.1 - 2.9e-83 273.2 60.6 3.7e-09 36.9 0.1 19.9 12 4 8 21 21 21 19 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC76551.1 - 1.1e-72 231.2 53.8 0.0014 18.9 0.0 28.1 28 0 0 28 28 28 20 Ankyrin repeat Ank PF00023.30 PSC76551.1 - 5.5e-68 222.6 93.8 7.1e-06 26.2 0.1 26.6 26 0 0 26 26 26 20 Ankyrin repeat 4HBT PF03061.22 PSC76552.1 - 7.4e-06 26.2 0.0 1.2e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily A_thal_3526 PF09713.10 PSC76553.1 - 4.5e-25 87.7 3.9 6.4e-25 87.2 3.9 1.2 1 0 0 1 1 1 1 Plant protein 1589 of unknown function (A_thal_3526) DUF2722 PF10846.8 PSC76553.1 - 0.0097 14.9 2.1 0.013 14.5 2.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Spt20 PF12090.8 PSC76553.1 - 0.11 12.1 12.4 0.17 11.5 12.4 1.2 1 0 0 1 1 1 0 Spt20 family MFS_1 PF07690.16 PSC76554.1 - 2.9e-27 95.6 42.6 4.1e-26 91.8 38.1 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily zf-CCCH PF00642.24 PSC76554.1 - 2e-12 46.7 16.6 1.1e-09 37.9 2.9 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 PSC76554.1 - 7e-07 29.1 3.1 7e-07 29.1 3.1 2.5 2 0 0 2 2 2 1 Zinc finger domain zf-CCCH_4 PF18044.1 PSC76554.1 - 4.1e-06 26.5 14.4 0.00012 21.8 1.0 2.4 2 0 0 2 2 2 2 CCCH-type zinc finger DprA_WH PF17782.1 PSC76554.1 - 0.00032 20.8 0.3 0.00032 20.8 0.3 2.9 2 0 0 2 2 2 1 DprA winged helix domain zf-CCCH_2 PF14608.6 PSC76554.1 - 0.0014 19.0 2.9 0.0014 19.0 2.9 2.5 2 0 0 2 2 2 1 RNA-binding, Nab2-type zinc finger Torus PF16131.5 PSC76554.1 - 0.011 16.4 4.4 0.073 13.8 0.2 2.3 2 0 0 2 2 2 0 Torus domain Rrf2 PF02082.20 PSC76554.1 - 0.013 15.8 0.0 0.029 14.7 0.0 1.5 1 0 0 1 1 1 0 Transcriptional regulator MarR_2 PF12802.7 PSC76554.1 - 0.03 14.2 0.1 0.19 11.7 0.1 2.3 2 0 0 2 2 2 0 MarR family TrmB PF01978.19 PSC76554.1 - 0.058 13.3 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF742 PF05331.11 PSC76554.1 - 1 9.2 3.0 31 4.4 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF742) OATP PF03137.20 PSC76554.1 - 2.5 6.3 12.5 0.036 12.4 0.3 2.7 1 1 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family WD40 PF00400.32 PSC76556.1 - 7.7e-23 80.4 3.2 2.3e-06 28.2 0.0 5.3 5 0 0 5 5 5 4 WD domain, G-beta repeat SRR1 PF07985.12 PSC76556.1 - 4.9e-10 39.3 0.1 1.2e-09 38.0 0.1 1.7 1 0 0 1 1 1 1 SRR1 ANAPC4_WD40 PF12894.7 PSC76556.1 - 6.3e-06 26.4 0.0 0.034 14.4 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain VHL PF01847.16 PSC76557.1 - 5.6e-20 71.0 0.1 1.2e-19 70.0 0.1 1.5 1 0 0 1 1 1 1 VHL beta domain T3SS_needle_E PF08988.10 PSC76557.1 - 0.076 13.2 2.1 0.63 10.2 0.1 2.5 2 0 0 2 2 2 0 Type III secretion system, cytoplasmic E component of needle PPTA PF01239.22 PSC76558.1 - 8e-27 92.1 11.3 8.7e-07 28.5 0.1 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat GST_C_2 PF13410.6 PSC76558.1 - 0.15 12.1 0.3 0.15 12.1 0.3 2.8 3 0 0 3 3 3 0 Glutathione S-transferase, C-terminal domain DUF4219 PF13961.6 PSC76558.1 - 7.6 6.3 9.1 9.6 6.0 0.0 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4219) DUF1538 PF07556.11 PSC76559.1 - 0.02 14.2 1.2 0.035 13.4 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1538) CCER1 PF15482.6 PSC76559.1 - 0.12 12.2 0.6 0.27 11.1 0.6 1.5 1 0 0 1 1 1 0 Coiled-coil domain-containing glutamate-rich protein family 1 Bestrophin PF01062.21 PSC76560.1 - 3.3e-16 59.5 0.1 4.1e-16 59.2 0.1 1.1 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Methyltransf_11 PF08241.12 PSC76561.1 - 1.9e-19 70.1 0.0 1.9e-18 66.9 0.0 2.2 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC76561.1 - 1.6e-14 54.4 0.0 1.8e-13 51.0 0.0 2.2 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 PSC76561.1 - 7.3e-13 48.7 0.0 1.2e-12 48.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 PSC76561.1 - 1.3e-09 37.7 0.0 1.9e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 PSC76561.1 - 8.3e-09 36.1 0.0 2.6e-08 34.5 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC76561.1 - 2e-07 30.9 0.0 3.1e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 PSC76561.1 - 0.00077 19.4 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Hypothetical methyltransferase Pet191_N PF10203.9 PSC76562.1 - 0.066 13.5 0.2 0.091 13.1 0.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Chorismate_bind PF00425.18 PSC76563.1 - 3.8e-88 295.4 0.0 5.5e-88 294.9 0.0 1.2 1 0 0 1 1 1 1 chorismate binding enzyme GATase PF00117.28 PSC76563.1 - 4e-32 111.5 0.0 5.8e-23 81.6 0.0 2.3 2 0 0 2 2 2 2 Glutamine amidotransferase class-I Anth_synt_I_N PF04715.13 PSC76563.1 - 1.6e-12 47.8 0.0 5.7e-11 42.8 0.0 3.0 2 1 0 2 2 2 1 Anthranilate synthase component I, N terminal region Peptidase_C26 PF07722.13 PSC76563.1 - 7.5e-06 25.9 0.4 8.5e-05 22.4 0.4 2.1 1 1 0 1 1 1 1 Peptidase C26 Trypsin PF00089.26 PSC76564.1 - 4.3e-30 105.2 0.3 1.1e-29 103.8 0.3 1.6 1 1 0 1 1 1 1 Trypsin ThiS PF02597.20 PSC76565.1 - 1.4e-16 60.9 0.0 1.5e-16 60.8 0.0 1.0 1 0 0 1 1 1 1 ThiS family PMI_typeI PF01238.21 PSC76565.1 - 0.044 13.0 0.0 0.048 12.8 0.0 1.0 1 0 0 1 1 1 0 Phosphomannose isomerase type I TrkA_C PF02080.21 PSC76565.1 - 0.089 12.6 0.0 0.19 11.6 0.0 1.5 2 0 0 2 2 2 0 TrkA-C domain Vma12 PF11712.8 PSC76566.1 - 1.5e-07 31.5 0.0 2.9e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Endoplasmic reticulum-based factor for assembly of V-ATPase Competence PF03772.16 PSC76566.1 - 0.0073 15.6 0.0 0.0092 15.3 0.0 1.1 1 0 0 1 1 1 1 Competence protein HicB PF05534.12 PSC76566.1 - 2.6 8.0 6.4 29 4.6 0.1 3.6 4 0 0 4 4 4 0 HicB family Acylphosphatase PF00708.18 PSC76567.1 - 1.2e-19 70.5 0.2 2.1e-19 69.7 0.2 1.4 1 0 0 1 1 1 1 Acylphosphatase Met_10 PF02475.16 PSC76567.1 - 0.001 18.9 0.0 0.0018 18.1 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein MTS PF05175.14 PSC76567.1 - 0.0013 18.3 0.0 0.0026 17.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 PSC76567.1 - 0.0055 17.4 0.2 0.021 15.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Gly_transf_sug PF04488.15 PSC76567.1 - 0.0079 16.8 0.0 0.015 15.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif Methyltransf_31 PF13847.6 PSC76567.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 PSC76567.1 - 0.089 13.4 0.0 0.24 12.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Polyketide_cyc PF03364.20 PSC76568.1 - 9.2e-06 25.9 0.0 1.4e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF220 PF02713.14 PSC76568.1 - 3.2e-05 24.0 0.0 5.9e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function DUF220 Polyketide_cyc2 PF10604.9 PSC76568.1 - 3.6e-05 24.1 0.0 9.5e-05 22.7 0.0 1.8 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport DUF1416 PF07210.12 PSC76568.1 - 0.013 15.3 0.1 0.033 14.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1416) Ribosomal_60s PF00428.19 PSC76568.1 - 0.071 13.7 7.5 0.19 12.4 7.5 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein Myb_DNA-binding PF00249.31 PSC76569.1 - 3.8e-08 33.4 0.0 0.0098 16.1 0.0 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC76569.1 - 0.018 15.3 0.0 8.6 6.7 0.0 2.6 2 0 0 2 2 2 0 Myb-like DNA-binding domain AAA_lid_2 PF17863.1 PSC76570.1 - 1e-16 60.5 1.0 1e-16 60.5 1.0 2.4 2 1 0 2 2 1 1 AAA lid domain VWA_2 PF13519.6 PSC76570.1 - 3.1e-13 50.3 0.0 1e-12 48.6 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain Mg_chelatase PF01078.21 PSC76570.1 - 1.1e-09 38.0 0.8 1.4e-08 34.3 0.8 2.2 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI VWA PF00092.28 PSC76570.1 - 2.4e-07 31.2 0.0 4.7e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain MCM PF00493.23 PSC76570.1 - 0.0001 21.5 0.0 0.00065 18.9 0.0 2.1 2 1 0 2 2 2 1 MCM P-loop domain AAA_5 PF07728.14 PSC76570.1 - 0.00021 21.3 0.0 0.0046 16.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 PSC76570.1 - 0.0022 17.8 0.0 0.22 11.2 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain CCDC53 PF10152.9 PSC76570.1 - 0.028 14.9 4.6 0.073 13.5 4.6 1.8 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Mito_fiss_reg PF05308.11 PSC76570.1 - 0.064 13.3 6.3 0.18 11.9 6.3 1.7 1 0 0 1 1 1 0 Mitochondrial fission regulator FAM176 PF14851.6 PSC76570.1 - 0.17 11.5 3.5 0.46 10.1 3.5 1.6 1 0 0 1 1 1 0 FAM176 family AAA_lid_8 PF17868.1 PSC76570.1 - 0.18 11.7 0.0 0.37 10.7 0.0 1.4 1 0 0 1 1 1 0 AAA lid domain CAP_N PF01213.19 PSC76570.1 - 0.18 11.3 10.3 0.38 10.2 10.3 1.4 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal CDC45 PF02724.14 PSC76570.1 - 0.23 9.7 1.9 0.33 9.2 1.9 1.2 1 0 0 1 1 1 0 CDC45-like protein VIR_N PF15912.5 PSC76570.1 - 0.29 10.7 8.7 0.52 9.9 8.7 1.4 1 0 0 1 1 1 0 Virilizer, N-terminal PAXIP1_C PF15364.6 PSC76570.1 - 0.42 10.9 10.5 1 9.7 10.5 1.6 1 0 0 1 1 1 0 PAXIP1-associated-protein-1 C term PTIP binding protein DUF3391 PF11871.8 PSC76570.1 - 1.2 9.7 13.4 0.13 12.8 4.6 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF3391) TFIIF_alpha PF05793.12 PSC76570.1 - 9.9 4.6 11.4 16 4.0 11.4 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Gly_transf_sug PF04488.15 PSC76571.1 - 7.7e-08 32.9 0.0 1.4e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase sugar-binding region containing DXD motif DPBB_1 PF03330.18 PSC76571.1 - 0.0002 21.5 0.1 0.00049 20.3 0.1 1.6 1 0 0 1 1 1 1 Lytic transglycolase Methyltransf_25 PF13649.6 PSC76571.1 - 0.0082 16.8 0.0 0.027 15.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Caps_synth PF05704.12 PSC76571.1 - 0.098 12.0 0.0 0.15 11.4 0.0 1.1 1 0 0 1 1 1 0 Capsular polysaccharide synthesis protein cobW PF02492.19 PSC76572.1 - 2.8e-40 137.8 0.1 4.2e-40 137.2 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 PSC76572.1 - 6.8e-23 80.4 0.1 1.3e-22 79.5 0.1 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain TsaE PF02367.17 PSC76572.1 - 0.0031 17.5 0.0 0.006 16.6 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 PSC76572.1 - 0.0055 16.6 0.2 1.5 8.7 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 PSC76572.1 - 0.0095 16.1 0.1 0.024 14.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PSC76572.1 - 0.1 13.0 0.0 0.24 11.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain cobW PF02492.19 PSC76573.1 - 2.8e-40 137.8 0.1 4.2e-40 137.2 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 PSC76573.1 - 6.9e-23 80.4 0.1 1.3e-22 79.5 0.1 1.5 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain TsaE PF02367.17 PSC76573.1 - 0.003 17.6 0.0 0.0057 16.6 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 PSC76573.1 - 0.0056 16.6 0.3 1.5 8.7 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase AAA_33 PF13671.6 PSC76573.1 - 0.0096 16.1 0.1 0.024 14.8 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 PSC76573.1 - 0.092 13.1 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain EST1_DNA_bind PF10373.9 PSC76574.1 - 0.0064 16.0 0.1 0.0086 15.6 0.1 1.2 1 0 0 1 1 1 1 Est1 DNA/RNA binding domain FlaF PF07309.11 PSC76574.1 - 0.017 15.1 4.3 0.1 12.6 4.0 2.4 2 0 0 2 2 2 0 Flagellar protein FlaF CREPT PF16566.5 PSC76574.1 - 0.11 12.7 5.0 0.078 13.1 3.2 1.7 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour Tubulin PF00091.25 PSC76575.1 - 1.5e-39 136.2 0.9 6.6e-38 130.9 0.0 2.2 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_2 PF13809.6 PSC76575.1 - 0.025 13.8 0.0 0.048 12.8 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Tubulin_3 PF14881.6 PSC76575.1 - 0.22 11.2 0.0 0.37 10.4 0.0 1.3 1 0 0 1 1 1 0 Tubulin domain Dynamin_N PF00350.23 PSC76576.1 - 2e-31 109.3 0.0 4.5e-31 108.2 0.0 1.7 1 0 0 1 1 1 1 Dynamin family TauE PF01925.19 PSC76576.1 - 3e-22 79.4 46.6 2.4e-14 53.5 21.2 2.4 3 0 0 3 3 3 2 Sulfite exporter TauE/SafE MMR_HSR1 PF01926.23 PSC76576.1 - 0.00013 22.0 0.0 0.00031 20.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase LD_cluster2 PF18163.1 PSC76576.1 - 0.0073 15.9 0.0 0.013 15.0 0.0 1.4 1 0 0 1 1 1 1 SLOG cluster2 AAA_16 PF13191.6 PSC76576.1 - 0.021 15.2 1.0 0.24 11.8 0.0 2.8 3 0 0 3 3 3 0 AAA ATPase domain CCDC-167 PF15188.6 PSC76576.1 - 5.6 7.4 5.7 44 4.5 1.1 2.9 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 167 DDHD PF02862.17 PSC76577.1 - 1e-37 130.5 0.0 1.8e-37 129.7 0.0 1.4 1 0 0 1 1 1 1 DDHD domain Ank_5 PF13857.6 PSC76577.1 - 2.2e-10 40.6 5.0 0.00011 22.4 0.2 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 PSC76577.1 - 3.3e-10 40.4 0.6 5.4e-06 26.9 0.1 3.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 PSC76577.1 - 9.8e-09 35.6 2.4 4.3e-05 24.0 0.2 4.4 3 1 1 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 PSC76577.1 - 3.3e-06 27.0 2.2 0.16 12.6 0.1 5.0 5 0 0 5 5 5 2 Ankyrin repeat Ank PF00023.30 PSC76577.1 - 0.00091 19.6 9.2 0.01 16.2 0.1 4.4 4 0 0 4 4 4 1 Ankyrin repeat BolA PF01722.18 PSC76578.1 - 8.6e-15 54.8 0.1 1.4e-14 54.2 0.1 1.5 1 1 0 1 1 1 1 BolA-like protein YwqJ-deaminase PF14431.6 PSC76578.1 - 0.11 12.7 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 YwqJ-like deaminase DUF92 PF01940.16 PSC76579.1 - 3e-71 239.6 4.7 3e-71 239.6 4.7 1.6 1 1 1 2 2 2 1 Integral membrane protein DUF92 PI31_Prot_N PF11566.8 PSC76580.1 - 3.4e-12 46.5 0.0 4.7e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 PSC76580.1 - 4.3e-08 34.2 17.1 4.3e-08 34.2 17.1 3.5 3 1 1 4 4 4 1 PI31 proteasome regulator p450 PF00067.22 PSC76581.1 - 1.5e-66 225.1 0.0 3.4e-47 161.3 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 p450 PF00067.22 PSC76582.1 - 8.5e-67 225.9 0.0 2.8e-47 161.5 0.0 1.9 2 0 0 2 2 2 2 Cytochrome P450 SOUL PF04832.12 PSC76583.1 - 8.2e-45 153.0 0.0 9.6e-45 152.8 0.0 1.1 1 0 0 1 1 1 1 SOUL heme-binding protein SBP56 PF05694.11 PSC76584.1 - 2.4e-10 39.8 0.0 3.2e-05 23.0 0.0 2.2 2 0 0 2 2 2 2 56kDa selenium binding protein (SBP56) CBM_14 PF01607.24 PSC76584.1 - 0.00014 21.9 3.6 0.0022 18.1 3.6 2.4 1 1 0 1 1 1 1 Chitin binding Peritrophin-A domain Lactonase PF10282.9 PSC76584.1 - 0.0076 15.5 0.0 3.5 6.8 0.0 2.2 2 0 0 2 2 2 2 Lactonase, 7-bladed beta-propeller DUF1513 PF07433.11 PSC76584.1 - 0.0086 15.2 0.4 0.1 11.7 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1513) MIP PF00230.20 PSC76585.1 - 1.8e-32 112.9 20.4 9.8e-21 74.5 3.2 3.0 1 1 1 2 2 2 2 Major intrinsic protein DUF2371 PF10177.9 PSC76585.1 - 0.11 12.6 1.1 0.18 12.0 1.1 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) Spc7 PF08317.11 PSC76586.1 - 4.7 6.0 33.7 0.06 12.2 13.2 2.7 2 1 0 2 2 2 0 Spc7 kinetochore protein Peptidase_S8 PF00082.22 PSC76587.1 - 8.1e-41 140.2 11.3 8.1e-41 140.2 11.3 1.5 2 0 0 2 2 2 1 Subtilase family Dickkopf_N PF04706.12 PSC76587.1 - 4.2 7.9 22.4 1.1 9.8 12.2 2.4 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region DEAD PF00270.29 PSC76590.1 - 3.7e-31 108.2 0.0 6.4e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC76590.1 - 8.3e-21 74.4 0.0 2.1e-20 73.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC76590.1 - 1.4e-05 25.2 0.0 0.00014 21.9 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 PSC76590.1 - 8.2e-05 23.0 0.8 0.0069 16.7 0.1 2.7 2 0 0 2 2 2 1 AAA domain UvrD-helicase PF00580.21 PSC76590.1 - 0.0027 17.3 1.0 0.0074 15.8 0.1 2.2 3 0 0 3 3 3 1 UvrD/REP helicase N-terminal domain CMS1 PF14617.6 PSC76590.1 - 0.014 14.7 0.2 0.14 11.4 0.0 2.2 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit MAJIN PF15077.6 PSC76590.1 - 0.85 9.4 2.3 1.8 8.3 2.3 1.5 1 0 0 1 1 1 0 Membrane-anchored junction protein PhoH PF02562.16 PSC76590.1 - 3.5 7.0 5.8 1.6 8.1 0.1 2.3 2 0 0 2 2 2 0 PhoH-like protein Alb1 PF09135.11 PSC76591.1 - 0.55 11.1 13.6 0.8 10.6 12.8 1.7 1 1 0 1 1 1 0 Alb1 PIP5K PF01504.18 PSC76592.1 - 4.1e-80 268.9 0.0 3.9e-61 206.7 0.0 2.2 2 0 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase MORN PF02493.20 PSC76592.1 - 7.3e-41 135.7 68.2 1.9e-06 27.4 1.2 8.7 8 0 0 8 8 8 8 MORN repeat DRIM PF07539.12 PSC76593.1 - 2.1e-87 293.9 0.0 1.6e-83 281.1 0.0 4.3 4 1 0 4 4 4 2 Down-regulated in metastasis MMS19_N PF14500.6 PSC76593.1 - 0.023 14.3 0.3 1.1 8.8 0.0 3.4 2 1 1 3 3 3 0 Dos2-interacting transcription regulator of RNA-Pol-II Far-17a_AIG1 PF04750.14 PSC76594.1 - 2.6e-19 69.3 7.2 3.6e-19 68.9 7.2 1.2 1 0 0 1 1 1 1 FAR-17a/AIG1-like protein UCH PF00443.29 PSC76595.1 - 1.7e-50 171.9 0.0 2.1e-50 171.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PSC76595.1 - 7.6e-11 42.2 0.0 8.9e-10 38.7 0.0 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 PSC76595.1 - 0.0001 22.0 0.0 0.00022 20.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.6 PSC76595.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase PAH PF02671.21 PSC76596.1 - 4.2e-45 151.7 8.8 1.8e-17 63.2 0.1 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3a_C PF16879.5 PSC76596.1 - 9.1e-40 137.2 0.0 1.2e-37 130.2 0.0 3.3 3 1 0 3 3 3 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 PSC76596.1 - 1.3e-32 111.8 0.0 2.7e-32 110.7 0.0 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor Stealth_CR4 PF17103.5 PSC76596.1 - 0.12 12.3 0.0 0.43 10.5 0.0 2.0 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 GBS_Bsp-like PF08481.10 PSC76596.1 - 0.13 12.4 0.2 0.3 11.2 0.2 1.5 1 0 0 1 1 1 0 GBS Bsp-like repeat PAH PF02671.21 PSC76597.1 - 4.2e-45 151.6 8.8 1.8e-17 63.2 0.1 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3a_C PF16879.5 PSC76597.1 - 9.1e-40 137.2 0.0 1.2e-37 130.2 0.0 3.3 3 1 0 3 3 3 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 PSC76597.1 - 1.3e-32 111.8 0.0 2.7e-32 110.7 0.0 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor Stealth_CR4 PF17103.5 PSC76597.1 - 0.12 12.2 0.0 0.43 10.5 0.0 1.9 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 GBS_Bsp-like PF08481.10 PSC76597.1 - 0.13 12.4 0.2 0.3 11.2 0.2 1.5 1 0 0 1 1 1 0 GBS Bsp-like repeat PAH PF02671.21 PSC76598.1 - 4.3e-45 151.6 8.8 1.8e-17 63.2 0.1 3.8 3 0 0 3 3 3 3 Paired amphipathic helix repeat Sin3a_C PF16879.5 PSC76598.1 - 9.5e-40 137.1 0.0 1.2e-37 130.2 0.0 3.3 3 1 0 3 3 3 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 PSC76598.1 - 1.3e-32 111.7 0.0 2.8e-32 110.7 0.0 1.6 1 0 0 1 1 1 1 Sin3 family co-repressor Stealth_CR4 PF17103.5 PSC76598.1 - 0.12 12.2 0.0 0.44 10.5 0.0 1.9 1 0 0 1 1 1 0 Stealth protein CR4, conserved region 4 GBS_Bsp-like PF08481.10 PSC76598.1 - 0.13 12.4 0.2 0.3 11.2 0.2 1.5 1 0 0 1 1 1 0 GBS Bsp-like repeat Thioredoxin_8 PF13905.6 PSC76599.1 - 8.1e-30 103.0 0.0 1.2e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin PF00085.20 PSC76599.1 - 3.2e-08 33.5 0.0 3.8e-07 30.0 0.1 1.9 1 1 1 2 2 2 1 Thioredoxin Redoxin PF08534.10 PSC76599.1 - 1.1e-07 31.6 0.0 1.5e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 PSC76599.1 - 7.3e-07 29.1 0.0 1e-06 28.6 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_2 PF13098.6 PSC76599.1 - 0.00021 21.7 0.0 0.0003 21.2 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 PSC76599.1 - 0.00052 20.1 0.1 0.0013 18.9 0.1 1.7 1 1 0 1 1 1 1 Thioredoxin-like SCO1-SenC PF02630.14 PSC76599.1 - 0.00069 19.5 0.0 0.001 19.0 0.0 1.2 1 0 0 1 1 1 1 SCO1/SenC DUF953 PF06110.11 PSC76599.1 - 0.014 15.0 0.0 0.11 12.1 0.0 2.0 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF953) Thioredoxin_9 PF14595.6 PSC76599.1 - 0.073 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin Head-tail_con PF12236.8 PSC76599.1 - 0.12 10.8 0.0 0.17 10.3 0.0 1.2 1 0 0 1 1 1 0 Bacteriophage head to tail connecting protein Ribosomal_S19 PF00203.21 PSC76600.1 - 1.9e-34 117.4 0.2 2.4e-34 117.0 0.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S19 UPF0236 PF06782.11 PSC76600.1 - 0.014 14.1 0.1 0.017 13.8 0.1 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0236) ALC PF17527.2 PSC76600.1 - 0.038 13.6 1.0 0.17 11.5 1.0 1.7 1 1 1 2 2 2 0 Phage ALC protein rve PF00665.26 PSC76601.1 - 7.2e-19 68.1 0.0 1.7e-18 66.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC76601.1 - 0.0062 16.3 0.0 0.018 14.8 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain AAA_25 PF13481.6 PSC76601.1 - 0.028 14.0 2.6 2.6 7.6 0.3 3.3 2 1 0 2 2 2 0 AAA domain DUF4231 PF14015.6 PSC76602.1 - 0.044 14.3 6.5 1.9 9.0 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) RTA1 PF04479.13 PSC76602.1 - 1.4 8.5 5.6 0.83 9.2 1.2 2.1 1 1 1 2 2 2 0 RTA1 like protein Ank_5 PF13857.6 PSC76603.1 - 0.015 15.7 0.2 44 4.6 0.0 3.7 3 0 0 3 3 3 0 Ankyrin repeats (many copies) DUF202 PF02656.15 PSC76604.1 - 9.5 6.8 8.8 1.3 9.5 0.9 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF202) Med8 PF10232.9 PSC76605.1 - 2e-11 43.9 1.2 1e-10 41.6 1.2 2.1 1 1 0 1 1 1 1 Mediator of RNA polymerase II transcription complex subunit 8 p450 PF00067.22 PSC76605.1 - 8.3e-07 28.1 0.0 1.6e-05 23.9 0.0 2.1 2 0 0 2 2 2 1 Cytochrome P450 HisKA PF00512.25 PSC76605.1 - 0.25 11.4 4.3 5.8 7.0 1.1 3.4 2 1 0 2 2 2 0 His Kinase A (phospho-acceptor) domain SIMPL PF04402.14 PSC76605.1 - 7.2 7.0 8.2 16 5.9 5.8 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF541) p25-alpha PF05517.12 PSC76607.1 - 9.9e-33 113.5 0.1 1.2e-32 113.2 0.1 1.0 1 0 0 1 1 1 1 p25-alpha adh_short PF00106.25 PSC76608.1 - 2.7e-28 98.8 0.1 3.8e-28 98.3 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC76608.1 - 3.5e-21 75.8 0.6 4.8e-21 75.4 0.6 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC76608.1 - 5e-06 26.5 0.4 1.1e-05 25.5 0.4 1.6 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 PSC76608.1 - 0.0097 15.8 0.9 0.015 15.2 0.8 1.4 1 1 0 1 1 1 1 NAD(P)H-binding Tctex-1 PF03645.13 PSC76609.1 - 3e-19 69.2 0.0 3.6e-19 68.9 0.0 1.1 1 0 0 1 1 1 1 Tctex-1 family GAS PF13851.6 PSC76610.1 - 0.081 12.3 39.0 0.27 10.6 8.3 3.7 1 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 PSC76610.1 - 0.41 10.7 18.9 0.8 9.8 0.1 4.7 2 1 3 5 5 5 0 Protein of unknown function (DUF1664) DUF4600 PF15372.6 PSC76610.1 - 0.65 10.4 8.1 0.06 13.8 0.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4600) UBA PF00627.31 PSC76611.1 - 0.052 13.5 0.4 0.12 12.3 0.4 1.5 1 0 0 1 1 1 0 UBA/TS-N domain NAD_binding_2 PF03446.15 PSC76612.1 - 4.4e-16 59.4 0.0 7.2e-16 58.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 PSC76612.1 - 7e-11 42.4 0.1 1.5e-10 41.4 0.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Pectate_lyase_3 PF12708.7 PSC76612.1 - 1.6e-06 28.1 0.9 3.5e-06 27.0 0.2 1.8 2 0 0 2 2 2 1 Pectate lyase superfamily protein NAD_binding_2 PF03446.15 PSC76613.1 - 4.6e-16 59.4 0.0 7.3e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 PSC76613.1 - 7e-11 42.4 0.1 1.5e-10 41.4 0.1 1.5 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Pectate_lyase_3 PF12708.7 PSC76613.1 - 1.7e-06 28.1 0.9 3.6e-06 27.0 0.2 1.8 2 0 0 2 2 2 1 Pectate lyase superfamily protein Peptidase_S8 PF00082.22 PSC76614.1 - 4e-39 134.7 11.3 4.2e-39 134.6 4.3 3.1 2 1 0 2 2 2 1 Subtilase family PA PF02225.22 PSC76614.1 - 2.8e-12 46.5 0.5 2e-11 43.8 0.2 2.8 2 0 0 2 2 2 1 PA domain Y_Y_Y PF07495.13 PSC76614.1 - 1.2e-11 44.3 0.0 0.33 10.9 0.0 5.2 5 0 0 5 5 5 4 Y_Y_Y domain Big_3_3 PF13750.6 PSC76614.1 - 4.2e-09 36.2 3.9 0.061 13.0 0.1 5.9 6 0 0 6 6 6 2 Bacterial Ig-like domain (group 3) DUF4625 PF15418.6 PSC76614.1 - 0.00015 22.0 0.2 22 5.3 0.0 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4625) Big_3_2 PF12245.8 PSC76614.1 - 0.0029 17.9 0.3 15 5.9 0.0 4.7 4 0 0 4 4 4 1 Bacterial Ig-like domain Cadherin PF00028.17 PSC76614.1 - 0.0042 17.5 0.1 1.1 9.7 0.0 3.7 2 1 0 3 3 3 1 Cadherin domain Big_3_4 PF13754.6 PSC76614.1 - 0.0056 16.4 0.0 0.97 9.2 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function TcfC PF16967.5 PSC76614.1 - 0.073 12.6 0.0 7.2 6.2 0.0 3.4 3 0 0 3 3 3 0 E-set like domain UIM PF02809.20 PSC76614.1 - 0.12 12.4 15.9 0.2 11.7 2.3 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif Peptidase_S8 PF00082.22 PSC76615.1 - 4.2e-39 134.6 4.3 4.2e-39 134.6 4.3 3.1 2 1 0 3 3 3 1 Subtilase family PA PF02225.22 PSC76615.1 - 3e-12 46.4 0.5 2e-11 43.8 0.2 2.7 2 0 0 2 2 2 1 PA domain Y_Y_Y PF07495.13 PSC76615.1 - 1.2e-11 44.4 0.0 0.33 10.9 0.0 5.2 5 0 0 5 5 5 4 Y_Y_Y domain Big_3_3 PF13750.6 PSC76615.1 - 1.1e-08 34.8 4.5 0.061 13.0 0.1 5.7 6 0 0 6 6 6 2 Bacterial Ig-like domain (group 3) DUF4625 PF15418.6 PSC76615.1 - 0.00015 22.0 0.2 22 5.3 0.0 4.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4625) Big_3_2 PF12245.8 PSC76615.1 - 0.0029 17.9 0.3 14 5.9 0.0 4.7 4 0 0 4 4 4 1 Bacterial Ig-like domain Cadherin PF00028.17 PSC76615.1 - 0.0042 17.5 0.1 1.1 9.7 0.0 3.7 2 1 0 3 3 3 1 Cadherin domain Big_3_4 PF13754.6 PSC76615.1 - 0.0056 16.4 0.0 0.96 9.2 0.0 3.2 3 0 0 3 3 3 1 Domain of unknown function TcfC PF16967.5 PSC76615.1 - 0.073 12.6 0.0 7.2 6.2 0.0 3.4 3 0 0 3 3 3 0 E-set like domain UIM PF02809.20 PSC76615.1 - 0.11 12.4 15.9 0.2 11.7 2.3 2.6 2 0 0 2 2 2 0 Ubiquitin interaction motif Myb_DNA-binding PF00249.31 PSC76616.1 - 2.9e-42 142.6 20.1 3.4e-16 59.2 0.0 6.5 5 1 0 5 5 5 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC76616.1 - 1.1e-32 112.1 1.4 2.2e-10 40.6 0.0 6.5 5 1 1 6 6 6 5 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PSC76616.1 - 0.00073 19.4 0.0 0.0049 16.7 0.0 2.4 2 0 0 2 2 2 1 Myb DNA-binding like HNH_3 PF13392.6 PSC76616.1 - 0.42 10.4 1.5 2.9 7.7 0.2 2.4 2 0 0 2 2 2 0 HNH endonuclease DUF572 PF04502.13 PSC76616.1 - 1.1 8.8 30.7 3.2 7.3 12.0 2.7 2 0 0 2 2 2 0 Family of unknown function (DUF572) PPP4R2 PF09184.11 PSC76616.1 - 6.4 6.3 22.4 0.48 10.0 7.7 2.3 2 0 0 2 2 2 0 PPP4R2 Rap1_C PF11626.8 PSC76616.1 - 8.8 6.5 12.0 0.39 10.8 0.3 4.3 3 1 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Nop14 PF04147.12 PSC76616.1 - 8.9 4.4 28.6 0.027 12.7 5.0 2.2 2 0 0 2 2 2 0 Nop14-like family EXS PF03124.14 PSC76617.1 - 0.04 13.3 0.5 0.073 12.4 0.5 1.4 1 0 0 1 1 1 0 EXS family Mem_trans PF03547.18 PSC76619.1 - 5.3e-20 71.2 13.3 5.3e-20 71.2 13.3 4.3 3 2 0 3 3 3 1 Membrane transport protein zf-C2H2_jaz PF12171.8 PSC76619.1 - 0.0011 19.2 2.2 0.11 12.9 0.0 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding LMBR1 PF04791.16 PSC76619.1 - 0.21 10.5 31.3 0.36 9.7 0.7 2.4 2 0 0 2 2 2 0 LMBR1-like membrane protein zf-H2C2_2 PF13465.6 PSC76619.1 - 0.25 11.8 4.9 3.9 8.1 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 PSC76619.1 - 0.59 11.1 4.4 16 6.7 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-LYAR PF08790.11 PSC76619.1 - 4.8 7.2 9.2 8.6 6.4 7.4 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger Mem_trans PF03547.18 PSC76620.1 - 8.2e-17 60.7 7.8 8.2e-17 60.7 7.8 4.3 3 2 0 3 3 3 1 Membrane transport protein zf-C2H2_jaz PF12171.8 PSC76620.1 - 0.00097 19.4 2.2 0.1 12.9 0.0 2.8 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding LMBR1 PF04791.16 PSC76620.1 - 0.18 10.6 31.3 0.34 9.8 0.7 2.4 2 0 0 2 2 2 0 LMBR1-like membrane protein zf-H2C2_2 PF13465.6 PSC76620.1 - 0.22 12.0 4.9 3.8 8.1 0.1 2.5 2 0 0 2 2 2 0 Zinc-finger double domain zf-C2H2_4 PF13894.6 PSC76620.1 - 0.52 11.3 4.4 15 6.8 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-LYAR PF08790.11 PSC76620.1 - 4.4 7.3 9.2 8.2 6.4 7.4 2.3 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger TFIIA PF03153.13 PSC76621.1 - 0.015 15.3 33.9 0.018 15.1 33.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF445 PF04286.12 PSC76621.1 - 0.058 13.2 6.9 0.075 12.8 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF445) RR_TM4-6 PF06459.12 PSC76621.1 - 0.075 12.8 5.9 0.1 12.4 5.9 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 MDM31_MDM32 PF08118.11 PSC76621.1 - 0.14 10.8 3.5 0.18 10.4 3.5 1.1 1 0 0 1 1 1 0 Yeast mitochondrial distribution and morphology (MDM) proteins DDHD PF02862.17 PSC76621.1 - 0.16 12.1 4.3 0.18 11.9 4.3 1.2 1 0 0 1 1 1 0 DDHD domain Ppx-GppA PF02541.16 PSC76621.1 - 0.2 11.1 5.5 0.26 10.7 5.5 1.2 1 0 0 1 1 1 0 Ppx/GppA phosphatase family XRN_M PF17846.1 PSC76621.1 - 0.24 10.3 7.2 0.3 10.0 7.2 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Presenilin PF01080.17 PSC76621.1 - 0.25 10.1 7.7 0.26 10.0 7.7 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 PSC76621.1 - 0.3 9.7 12.1 0.36 9.5 12.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4449 PF14613.6 PSC76621.1 - 0.34 11.0 15.6 0.5 10.5 15.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4449) LIM_bind PF01803.16 PSC76621.1 - 0.37 10.3 13.4 0.56 9.7 13.4 1.2 1 0 0 1 1 1 0 LIM-domain binding protein DUF935 PF06074.12 PSC76621.1 - 0.43 9.3 17.7 0.55 8.9 17.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) GREB1 PF15782.5 PSC76621.1 - 0.66 7.0 10.7 0.72 6.9 10.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Nha1_C PF08619.10 PSC76621.1 - 0.79 8.9 10.6 0.91 8.7 10.6 1.1 1 0 0 1 1 1 0 Alkali metal cation/H+ antiporter Nha1 C terminus Lin-8 PF03353.15 PSC76621.1 - 1.1 8.7 11.9 1.3 8.5 11.9 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist PAT1 PF09770.9 PSC76621.1 - 1.3 7.2 25.1 1.5 7.0 25.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 UPF0565 PF10561.9 PSC76621.1 - 1.3 8.1 6.6 1.7 7.8 6.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0565 EPL1 PF10513.9 PSC76621.1 - 1.3 9.4 5.8 1.7 9.0 5.8 1.3 1 0 0 1 1 1 0 Enhancer of polycomb-like Med15 PF09606.10 PSC76621.1 - 1.6 7.3 32.2 1.8 7.2 32.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Spore_coat_CotO PF14153.6 PSC76621.1 - 2.2 8.2 23.8 2.9 7.8 23.8 1.1 1 0 0 1 1 1 0 Spore coat protein CotO DUF4400 PF14348.6 PSC76621.1 - 2.2 7.7 9.4 3.4 7.1 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4400) CCSAP PF15748.5 PSC76621.1 - 3 8.0 15.3 4 7.5 15.3 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated FUSC PF04632.12 PSC76621.1 - 3.9 5.9 25.5 5 5.5 25.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Neur_chan_memb PF02932.16 PSC76621.1 - 7.7 6.5 9.4 10 6.1 9.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AAA_23 PF13476.6 PSC76621.1 - 7.9 6.9 12.2 11 6.5 12.2 1.2 1 0 0 1 1 1 0 AAA domain MMR1 PF08505.10 PSC76621.1 - 8.2 6.6 13.8 12 6.1 13.8 1.2 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Kei1 PF08552.11 PSC76621.1 - 9.9 6.0 10.2 16 5.3 10.2 1.5 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Med7 PF05983.11 PSC76622.1 - 2.1e-30 106.3 3.9 4.9e-29 101.8 3.9 2.0 1 1 0 1 1 1 1 MED7 protein ZapD PF07072.11 PSC76622.1 - 0.018 14.8 0.6 0.025 14.3 0.6 1.2 1 0 0 1 1 1 0 Cell division protein HBM PF16591.5 PSC76622.1 - 0.021 14.3 4.5 0.026 13.9 4.5 1.2 1 0 0 1 1 1 0 Helical bimodular sensor domain Resolvase PF00239.21 PSC76622.1 - 0.089 12.9 1.5 0.13 12.4 1.4 1.4 1 1 0 1 1 1 0 Resolvase, N terminal domain FlgN PF05130.12 PSC76622.1 - 1.4 9.5 9.0 4.1 7.9 9.0 1.8 1 1 0 1 1 1 0 FlgN protein 5_nucleotid_C PF02872.18 PSC76623.1 - 1.2e-37 129.5 0.0 2.8e-37 128.3 0.0 1.6 1 0 0 1 1 1 1 5'-nucleotidase, C-terminal domain Metallophos PF00149.28 PSC76623.1 - 0.00049 20.7 0.0 0.00079 20.0 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Q_salvage PF10343.9 PSC76624.1 - 1.2e-84 284.3 0.0 1.6e-84 283.9 0.0 1.2 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family STAS_2 PF13466.6 PSC76624.1 - 0.0091 16.3 0.9 0.0091 16.3 0.9 3.1 3 0 0 3 3 3 1 STAS domain WD40 PF00400.32 PSC76625.1 - 1.2e-06 29.1 3.3 0.18 12.7 0.0 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC76625.1 - 2.1e-06 28.0 0.0 2.2 8.6 0.1 4.7 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 PSC76625.1 - 0.0031 16.2 0.0 0.0066 15.1 0.0 1.5 2 0 0 2 2 2 1 Nucleoporin Nup120/160 DUF3551 PF12071.8 PSC76625.1 - 5.8 7.0 7.9 0.67 10.0 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3551) tRNA-synt_1 PF00133.22 PSC76626.1 - 5.7e-214 711.8 0.0 6.5e-213 708.3 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 PSC76626.1 - 1.5e-37 128.9 0.0 4e-37 127.5 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 PSC76626.1 - 3e-25 88.8 0.1 3.7e-13 49.0 0.1 3.5 2 2 0 2 2 2 2 tRNA synthetases class I (M) Val_tRNA-synt_C PF10458.9 PSC76626.1 - 1e-14 54.6 3.6 3.1e-14 53.0 3.6 1.9 1 0 0 1 1 1 1 Valyl tRNA synthetase tRNA binding arm tRNA-synt_1_2 PF13603.6 PSC76626.1 - 3.7e-10 39.6 0.0 4.6e-07 29.5 0.0 2.4 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 PSC76626.1 - 0.00012 21.6 0.0 0.0036 16.7 0.0 2.3 2 0 0 2 2 2 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 PSC76626.1 - 0.0015 17.5 0.0 0.0028 16.7 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (K) ABC_tran_CTD PF16326.5 PSC76626.1 - 0.39 11.0 7.3 0.039 14.2 1.8 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF2076 PF09849.9 PSC76626.1 - 4.3 7.3 19.1 0.029 14.4 5.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) HALZ PF02183.18 PSC76626.1 - 7.1 6.9 5.7 27 5.1 0.1 2.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper VHP PF02209.19 PSC76628.1 - 1.7e-10 40.8 0.1 1.7e-10 40.8 0.1 2.3 3 0 0 3 3 3 1 Villin headpiece domain Gelsolin PF00626.22 PSC76628.1 - 0.00034 20.4 2.5 0.00047 20.0 0.0 2.4 3 0 0 3 3 3 1 Gelsolin repeat DUF1757 PF08560.10 PSC76629.1 - 1.7e-06 28.2 0.1 2.1e-06 27.9 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) GH-E PF14410.6 PSC76630.1 - 0.1 13.0 0.1 0.23 11.9 0.1 1.5 1 0 0 1 1 1 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues Glyco_transf_90 PF05686.12 PSC76631.1 - 1.5e-39 136.0 0.0 1.4e-30 106.5 0.0 2.9 2 1 0 2 2 2 2 Glycosyl transferase family 90 DAZAP2 PF11029.8 PSC76631.1 - 0.0072 17.2 0.1 0.016 16.1 0.1 1.6 1 0 0 1 1 1 1 DAZ associated protein 2 (DAZAP2) WD40 PF00400.32 PSC76632.1 - 6.8e-15 55.2 0.6 3.1e-05 24.7 0.1 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC76632.1 - 2.1e-05 24.7 0.0 8.2 6.8 0.0 3.8 3 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 PSC76632.1 - 5.2 7.7 6.3 14 6.4 0.0 4.3 6 0 0 6 6 6 0 PQQ-like domain SUFU PF05076.13 PSC76633.1 - 0.00071 19.6 0.0 0.0036 17.3 0.0 1.9 1 1 0 1 1 1 1 Suppressor of fused protein (SUFU) LRR_8 PF13855.6 PSC76634.1 - 1.5e-11 43.9 1.5 5.1e-06 26.2 0.3 2.8 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PSC76634.1 - 2.7e-11 43.5 3.1 4.6e-06 26.9 0.4 3.5 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 PSC76634.1 - 0.00032 20.5 3.4 0.0018 18.2 3.4 2.3 1 1 0 1 1 1 1 F-box-like F-box PF00646.33 PSC76634.1 - 0.0012 18.7 0.3 0.5 10.3 0.0 3.1 3 0 0 3 3 3 1 F-box domain LRR_1 PF00560.33 PSC76634.1 - 0.0014 18.9 3.2 26 5.9 0.1 5.0 4 0 0 4 4 4 1 Leucine Rich Repeat LAP1C PF05609.12 PSC76634.1 - 0.48 9.4 6.4 0.68 9.0 6.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) TetR_C_20 PF17925.1 PSC76635.1 - 9.3 6.6 10.0 1.6 9.0 3.4 3.2 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Pex26 PF07163.12 PSC76636.1 - 0.00014 21.3 8.4 0.00014 21.3 8.4 2.3 1 1 1 2 2 2 1 Pex26 protein DUF1580 PF07618.11 PSC76636.1 - 0.13 11.9 0.3 0.56 9.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1580) Presenilin PF01080.17 PSC76636.1 - 0.53 9.0 1.9 0.64 8.7 1.9 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 PSC76636.1 - 1.4 8.8 17.3 2.2 8.2 17.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rrn6 PF10214.9 PSC76636.1 - 2.1 6.7 7.7 2.5 6.5 7.7 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4834 PF16118.5 PSC76636.1 - 2.9 8.9 4.5 6.1 7.9 4.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Pex14_N PF04695.13 PSC76636.1 - 3.8 8.1 13.4 7.8 7.1 13.4 1.5 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 PSC76636.1 - 10 5.7 13.3 15 5.1 13.3 1.3 1 0 0 1 1 1 0 Spt20 family RHH_1 PF01402.21 PSC76637.1 - 0.051 13.5 0.3 0.051 13.5 0.3 2.0 2 0 0 2 2 2 0 Ribbon-helix-helix protein, copG family Thioredoxin PF00085.20 PSC76638.1 - 3.1e-26 91.4 0.0 8.3e-26 90.0 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin ERp29 PF07749.12 PSC76638.1 - 4e-18 66.1 0.5 4e-18 66.1 0.5 2.3 2 0 0 2 2 2 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.6 PSC76638.1 - 2.5e-05 24.7 0.0 0.0001 22.7 0.0 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 PSC76638.1 - 4.1e-05 23.1 0.0 6.2e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_9 PF14595.6 PSC76638.1 - 0.03 14.1 0.2 0.088 12.6 0.2 1.8 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_7 PF13899.6 PSC76638.1 - 0.046 13.9 0.0 0.11 12.7 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin-like TraF PF13728.6 PSC76638.1 - 0.05 13.4 0.0 0.05 13.4 0.0 2.7 3 1 0 3 3 3 0 F plasmid transfer operon protein Thioredoxin_8 PF13905.6 PSC76638.1 - 0.067 13.5 0.0 0.37 11.2 0.0 2.1 1 1 1 2 2 2 0 Thioredoxin-like TBCC_N PF16752.5 PSC76638.1 - 0.22 12.0 0.1 0.22 12.0 0.1 2.4 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain Tub_N PF16322.5 PSC76638.1 - 9.6 6.5 13.1 5.2 7.4 9.8 1.9 2 0 0 2 2 2 0 Tubby N-terminal GATA PF00320.27 PSC76639.1 - 8.6e-05 22.1 3.1 0.00018 21.0 3.1 1.6 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_6 PF14599.6 PSC76639.1 - 0.099 12.7 0.8 0.22 11.5 0.2 1.8 2 0 0 2 2 2 0 Zinc-ribbon Zn_Tnp_IS91 PF14319.6 PSC76639.1 - 0.15 12.1 4.2 0.56 10.3 0.2 2.3 2 0 0 2 2 2 0 Transposase zinc-binding domain SBP_bac_3 PF00497.20 PSC76640.1 - 1.1e-21 77.3 0.0 1.8e-21 76.7 0.0 1.2 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 Lig_chan PF00060.26 PSC76640.1 - 3.4e-17 62.7 0.9 5.4e-17 62.0 0.9 1.3 1 0 0 1 1 1 1 Ligand-gated ion channel DUF4381 PF14316.6 PSC76640.1 - 0.17 12.2 4.4 0.23 11.7 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) 7TMR-DISM_7TM PF07695.11 PSC76640.1 - 0.66 9.8 13.9 3.6 7.4 10.1 2.1 2 0 0 2 2 2 0 7TM diverse intracellular signalling Fasciclin PF02469.22 PSC76641.1 - 4.1e-19 69.1 0.8 1.8e-16 60.6 0.1 2.2 2 0 0 2 2 2 2 Fasciclin domain DUF4127 PF13552.6 PSC76641.1 - 0.064 11.9 0.2 7.4 5.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4127) Nop53 PF07767.11 PSC76643.1 - 1.6e-60 205.6 14.8 1.6e-60 205.6 14.8 2.0 2 0 0 2 2 2 1 Nop53 (60S ribosomal biogenesis) Thiolase_N PF00108.23 PSC76644.1 - 3.4e-80 269.1 1.9 5e-80 268.6 1.9 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 PSC76644.1 - 9.6e-48 160.9 0.9 1.9e-47 159.9 0.9 1.5 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 PSC76644.1 - 0.00017 21.2 0.9 0.00017 21.2 0.9 2.3 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III_C PF08541.10 PSC76644.1 - 0.067 13.4 0.1 0.19 11.9 0.1 1.8 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Glyco_transf_90 PF05686.12 PSC76645.1 - 9.5e-31 107.1 0.0 9e-30 103.9 0.0 2.3 2 1 0 2 2 2 1 Glycosyl transferase family 90 SGL PF08450.12 PSC76645.1 - 1e-06 28.5 0.0 0.0035 17.0 0.0 2.7 2 1 1 3 3 3 2 SMP-30/Gluconolactonase/LRE-like region DUF5128 PF17170.4 PSC76645.1 - 5.1e-05 22.6 4.1 0.00012 21.4 0.0 3.2 3 1 1 4 4 4 2 6-bladed beta-propeller Glyco_trans_1_2 PF13524.6 PSC76645.1 - 0.0039 17.5 0.0 0.013 15.9 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 NHL PF01436.21 PSC76645.1 - 0.018 15.1 2.1 7.2 6.9 0.1 4.0 4 0 0 4 4 4 0 NHL repeat DUF4934 PF16288.5 PSC76645.1 - 0.021 14.7 0.0 2.8 7.9 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4934) JHBP PF06585.11 PSC76645.1 - 0.097 11.8 0.0 0.28 10.3 0.0 1.7 2 0 0 2 2 2 0 Haemolymph juvenile hormone binding protein (JHBP) GATA PF00320.27 PSC76646.1 - 8.5e-14 50.9 5.3 1.6e-13 50.0 5.3 1.4 1 0 0 1 1 1 1 GATA zinc finger Arteri_nsp7a PF16749.5 PSC76646.1 - 0.56 10.4 3.4 1.1 9.4 3.4 1.4 1 0 0 1 1 1 0 Arterivirus nonstructural protein 7 alpha Thioredoxin PF00085.20 PSC76647.1 - 1.2e-57 192.3 0.0 4.2e-29 100.6 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_2 PF13098.6 PSC76647.1 - 4.2e-10 40.0 1.0 0.00043 20.7 0.0 3.7 2 2 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 PSC76647.1 - 8.6e-07 29.1 0.0 0.035 14.3 0.0 3.2 4 0 0 4 4 4 2 Thioredoxin-like Thioredoxin_6 PF13848.6 PSC76647.1 - 4.7e-06 26.6 0.0 0.077 12.9 0.0 2.9 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_3 PF13192.6 PSC76647.1 - 0.0002 21.3 0.0 0.87 9.7 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin domain Thioredoxin_8 PF13905.6 PSC76647.1 - 0.0021 18.3 0.0 1.8 8.9 0.0 2.9 2 1 1 3 3 3 2 Thioredoxin-like OST3_OST6 PF04756.13 PSC76647.1 - 0.0085 15.5 0.0 2 7.7 0.0 2.2 2 0 0 2 2 2 2 OST3 / OST6 family, transporter family TraF PF13728.6 PSC76647.1 - 0.011 15.5 0.0 5.2 6.8 0.0 2.5 3 0 0 3 3 3 0 F plasmid transfer operon protein Aminotran_1_2 PF00155.21 PSC76648.1 - 3.9e-51 174.3 0.0 5e-51 174.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II MFS_1 PF07690.16 PSC76649.1 - 9.5e-48 162.9 31.4 1e-39 136.5 23.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PSC76649.1 - 3.8e-13 49.1 24.2 8.7e-12 44.6 24.3 2.4 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 PSC76649.1 - 7.1e-05 21.3 5.6 0.00088 17.7 3.6 2.5 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family DUF1404 PF07185.11 PSC76649.1 - 0.12 12.1 1.5 0.25 11.0 1.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1404) DUF2593 PF10767.9 PSC76649.1 - 0.12 12.4 0.5 0.32 11.1 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2593) RabGAP-TBC PF00566.18 PSC76650.1 - 9.4e-43 146.4 0.0 1.2e-42 146.0 0.0 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain PH_RBD PF12068.8 PSC76650.1 - 5e-20 71.6 0.0 1.3e-19 70.3 0.0 1.7 1 1 0 1 1 1 1 Rab-binding domain (RBD) Adenosine_kin PF04008.14 PSC76651.1 - 3.6e-63 212.0 0.0 5.7e-63 211.3 0.0 1.3 1 0 0 1 1 1 1 Adenosine specific kinase DUF974 PF06159.13 PSC76651.1 - 1.9e-36 126.1 0.0 3e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF974) Trs65 PF12735.7 PSC76651.1 - 0.19 11.1 0.0 1.4 8.2 0.0 2.0 2 0 0 2 2 2 0 TRAPP trafficking subunit Trs65 Metallophos PF00149.28 PSC76652.1 - 1.2e-12 48.8 0.2 1.8e-12 48.2 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ephrin_rec_like PF07699.13 PSC76652.1 - 7.3e-11 41.7 57.7 0.0033 17.1 3.2 7.6 3 3 5 8 8 8 6 Putative ephrin-receptor like Metallophos_2 PF12850.7 PSC76652.1 - 0.00015 22.0 0.0 0.016 15.4 0.0 2.7 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain TNFR_c6 PF00020.18 PSC76652.1 - 1 9.8 30.8 1.8 9.1 2.7 6.7 5 3 2 7 7 7 0 TNFR/NGFR cysteine-rich region zf-HC5HC2H PF13771.6 PSC76653.1 - 0.079 13.2 0.5 0.18 12.1 0.5 1.5 1 0 0 1 1 1 0 PHD-like zinc-binding domain Pkinase PF00069.25 PSC76654.1 - 6.7e-63 212.5 0.0 8.8e-36 123.6 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain PAS_9 PF13426.7 PSC76654.1 - 9.8e-41 138.2 0.0 6.6e-21 74.5 0.0 2.8 3 0 0 3 3 3 2 PAS domain Pkinase_Tyr PF07714.17 PSC76654.1 - 3.2e-30 105.3 0.0 2e-18 66.6 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase PAS PF00989.25 PSC76654.1 - 9.1e-12 45.0 0.0 0.00015 21.7 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_3 PF08447.12 PSC76654.1 - 1e-10 41.8 0.0 0.00039 20.7 0.0 2.6 2 0 0 2 2 2 2 PAS fold PAS_4 PF08448.10 PSC76654.1 - 4.9e-08 33.2 0.2 0.0016 18.7 0.0 3.1 3 0 0 3 3 3 2 PAS fold Kinase-like PF14531.6 PSC76654.1 - 0.00037 19.9 0.0 0.02 14.2 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 PSC76654.1 - 0.098 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF726 PF05277.12 PSC76655.1 - 0.0052 15.8 0.3 0.012 14.5 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF726) MFS_1_like PF12832.7 PSC76656.1 - 5.9e-23 81.3 8.2 6.8e-23 81.1 8.2 1.0 1 0 0 1 1 1 1 MFS_1 like family Nuc_H_symport PF03825.16 PSC76656.1 - 4.6e-05 22.6 0.6 5.2e-05 22.4 0.6 1.0 1 0 0 1 1 1 1 Nucleoside H+ symporter LacY_symp PF01306.19 PSC76656.1 - 0.053 12.3 1.6 0.15 10.8 0.1 1.9 2 0 0 2 2 2 0 LacY proton/sugar symporter BT1 PF03092.16 PSC76656.1 - 0.15 10.3 0.9 0.17 10.1 0.9 1.2 1 0 0 1 1 1 0 BT1 family DUF1757 PF08560.10 PSC76657.1 - 7.1e-09 35.9 0.0 8.8e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1757) DUF1772 PF08592.11 PSC76657.1 - 1.5 9.2 11.8 0.22 11.8 6.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1772) DUF4781 PF16013.5 PSC76657.1 - 4.7 5.9 11.4 0.056 12.2 2.8 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4781) Nucleotid_trans PF03407.16 PSC76658.1 - 6.6e-26 91.6 0.0 9.7e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Nucleotide-diphospho-sugar transferase Glyco_transf_34 PF05637.12 PSC76658.1 - 0.034 13.9 0.0 0.055 13.2 0.0 1.2 1 0 0 1 1 1 0 galactosyl transferase GMA12/MNN10 family IATP PF04568.12 PSC76660.1 - 0.0092 16.4 0.7 0.0092 16.4 0.7 2.5 2 0 0 2 2 2 1 Mitochondrial ATPase inhibitor, IATP PE PF00934.20 PSC76660.1 - 0.1 12.9 0.9 1.1 9.6 0.9 2.3 1 1 0 1 1 1 0 PE family Aa_trans PF01490.18 PSC76661.1 - 2.5e-149 497.5 40.8 3.9e-75 253.1 16.5 2.1 2 0 0 2 2 2 2 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 PSC76661.1 - 5.5e-14 52.0 12.0 6.7e-07 28.7 2.5 3.1 2 0 0 2 2 2 2 Tryptophan/tyrosine permease family HlyE PF06109.13 PSC76661.1 - 2.2e-06 27.2 2.3 0.021 14.1 0.1 2.3 2 0 0 2 2 2 2 Haemolysin E (HlyE) Ribosomal_S11 PF00411.19 PSC76661.1 - 0.014 15.8 0.5 12 6.3 0.1 2.9 2 0 0 2 2 2 0 Ribosomal protein S11 EpuA PF11772.8 PSC76661.1 - 0.061 13.0 0.3 31 4.4 0.0 3.5 2 0 0 2 2 2 0 DNA-directed RNA polymerase subunit beta NESP55 PF06390.12 PSC76661.1 - 0.22 11.1 6.9 3.3 7.2 0.1 2.7 3 0 0 3 3 3 0 Neuroendocrine-specific golgi protein P55 (NESP55) Bacteriocin_IId PF09221.10 PSC76661.1 - 4.2 7.6 13.6 10 6.4 1.0 4.7 4 0 0 4 4 4 0 Bacteriocin class IId cyclical uberolysin-like LRR_8 PF13855.6 PSC76662.1 - 0.025 14.4 0.0 0.28 11.0 0.1 2.4 2 1 0 2 2 2 0 Leucine rich repeat PQ-loop PF04193.14 PSC76663.1 - 9.6e-11 41.3 4.1 3.5e-07 29.9 0.3 2.6 2 0 0 2 2 2 2 PQ loop repeat ER_lumen_recept PF00810.18 PSC76663.1 - 0.033 15.0 3.5 0.72 10.7 0.0 2.3 2 0 0 2 2 2 0 ER lumen protein retaining receptor DUF3675 PF12428.8 PSC76663.1 - 0.092 13.3 0.1 0.19 12.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) CLPTM1 PF05602.12 PSC76664.1 - 3.1e-132 441.6 0.0 4.2e-132 441.2 0.0 1.2 1 0 0 1 1 1 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) ING PF12998.7 PSC76664.1 - 4.6e-18 65.7 3.8 9.4e-18 64.7 3.8 1.6 1 0 0 1 1 1 1 Inhibitor of growth proteins N-terminal histone-binding Ribosomal_L18p PF00861.22 PSC76664.1 - 7.1e-14 52.2 0.0 7.1e-14 52.2 0.0 1.8 2 0 0 2 2 2 1 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast Glyco_hydro_16 PF00722.21 PSC76664.1 - 2.3e-08 33.7 0.0 4.6e-08 32.7 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PHD PF00628.29 PSC76664.1 - 0.00025 20.8 8.6 0.00045 20.0 8.6 1.4 1 0 0 1 1 1 1 PHD-finger PQ-loop PF04193.14 PSC76664.1 - 0.00049 19.8 0.3 0.056 13.2 0.0 2.4 2 0 0 2 2 2 1 PQ loop repeat DHC_N1 PF08385.12 PSC76664.1 - 0.032 12.9 1.1 0.061 12.0 1.1 1.3 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 DUF2201_N PF13203.6 PSC76664.1 - 0.5 9.9 4.6 0.15 11.6 0.2 2.2 2 0 0 2 2 2 0 Putative metallopeptidase domain Ribosomal_S5 PF00333.20 PSC76665.1 - 0.078 13.0 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain Ribosomal_S5 PF00333.20 PSC76666.1 - 0.078 13.0 0.0 0.22 11.6 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S5, N-terminal domain Ald_Xan_dh_C2 PF02738.18 PSC76668.1 - 5.7e-190 632.4 1.5 8e-190 631.9 1.5 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 PSC76668.1 - 1.2e-48 165.1 0.0 2.3e-48 164.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain in molybdopterin dehydrogenase Ald_Xan_dh_C PF01315.22 PSC76668.1 - 4.3e-33 114.0 0.6 9.7e-33 112.8 0.6 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 PSC76668.1 - 6.1e-32 109.5 0.1 2.2e-31 107.7 0.1 2.1 1 0 0 1 1 1 1 [2Fe-2S] binding domain CO_deh_flav_C PF03450.17 PSC76668.1 - 1.2e-27 96.1 1.1 1.6e-26 92.5 0.2 2.8 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Fer2 PF00111.27 PSC76668.1 - 5.9e-10 39.0 0.4 5.9e-10 39.0 0.4 2.0 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 PSC76668.1 - 0.82 9.5 6.2 2.4 8.1 6.2 1.8 1 0 0 1 1 1 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B CTP_transf_3 PF02348.19 PSC76669.1 - 1.4e-52 178.8 0.1 4.7e-52 177.1 0.0 1.9 2 0 0 2 2 2 1 Cytidylyltransferase ABC1 PF03109.16 PSC76669.1 - 5.7e-38 129.7 0.0 1.7e-37 128.2 0.0 1.9 1 0 0 1 1 1 1 ABC1 family Bromodomain PF00439.25 PSC76669.1 - 1e-20 73.5 0.0 2.2e-20 72.5 0.0 1.5 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 PSC76669.1 - 1.3e-19 70.1 0.0 3.8e-19 68.6 0.0 1.9 1 0 0 1 1 1 1 Bromodomain extra-terminal - transcription regulation NTP_transf_3 PF12804.7 PSC76669.1 - 8.9e-10 39.1 1.7 1.9e-09 38.1 0.1 2.4 2 0 0 2 2 2 1 MobA-like NTP transferase domain DUF2064 PF09837.9 PSC76669.1 - 0.0035 17.1 0.5 0.013 15.3 0.5 2.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2064) APH PF01636.23 PSC76669.1 - 0.0038 17.2 0.0 0.0038 17.2 0.0 3.7 3 1 1 4 4 4 1 Phosphotransferase enzyme family NUDIX PF00293.28 PSC76670.1 - 1.4e-11 44.5 0.4 2.1e-11 44.0 0.4 1.2 1 0 0 1 1 1 1 NUDIX domain UQ_con PF00179.26 PSC76671.1 - 6.9e-36 123.0 0.0 8.8e-36 122.6 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DEAD PF00270.29 PSC76672.1 - 2.5e-42 144.6 0.0 6.5e-42 143.3 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC76672.1 - 7.9e-29 100.2 0.0 2.9e-27 95.2 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.6 PSC76672.1 - 0.083 12.2 0.3 0.24 10.7 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF4746 PF15928.5 PSC76672.1 - 1.1 8.7 8.9 0.091 12.2 3.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Sugar_tr PF00083.24 PSC76673.1 - 1.6e-100 337.1 24.4 5.2e-57 193.7 0.1 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 PSC76673.1 - 2.5e-15 56.3 25.0 2.5e-15 56.3 25.0 2.4 1 1 1 2 2 2 1 Major Facilitator Superfamily Rhodanese PF00581.20 PSC76673.1 - 2e-06 28.3 0.0 7.9e-06 26.3 0.0 2.0 1 1 0 1 1 1 1 Rhodanese-like domain Raffinose_syn PF05691.12 PSC76674.1 - 3e-09 35.3 0.0 3.4e-09 35.1 0.0 1.0 1 0 0 1 1 1 1 Raffinose synthase or seed imbibition protein Sip1 zf-RanBP PF00641.18 PSC76675.1 - 2.2e-16 58.8 11.7 2.6e-08 33.0 3.0 2.3 2 0 0 2 2 2 2 Zn-finger in Ran binding protein and others GRP PF07172.11 PSC76675.1 - 0.012 16.3 27.0 0.012 16.3 27.0 5.6 4 1 1 5 5 5 0 Glycine rich protein family TackOD1 PF18551.1 PSC76675.1 - 0.016 14.9 6.6 0.068 12.8 0.7 2.3 2 0 0 2 2 2 0 Thaumarchaeal output domain 1 LCD1 PF09798.9 PSC76675.1 - 0.91 8.0 5.5 1.1 7.7 5.5 1.2 1 0 0 1 1 1 0 DNA damage checkpoint protein SR-25 PF10500.9 PSC76675.1 - 5.1 6.7 52.8 0.031 13.9 28.2 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DZR PF12773.7 PSC76675.1 - 6.8 6.8 11.9 6.7 6.8 2.1 2.3 2 0 0 2 2 2 0 Double zinc ribbon HMG_box PF00505.19 PSC76676.1 - 3.5e-24 85.0 8.8 6e-18 65.0 0.3 2.7 2 0 0 2 2 2 2 HMG (high mobility group) box HMG_box_2 PF09011.10 PSC76676.1 - 1.4e-09 38.4 7.3 2e-05 25.1 0.4 2.7 2 0 0 2 2 2 2 HMG-box domain DUF572 PF04502.13 PSC76676.1 - 0.0064 16.2 1.1 0.0064 16.2 1.1 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF572) HMG_box_5 PF14887.6 PSC76676.1 - 0.052 13.5 1.4 0.21 11.6 0.0 2.7 1 1 1 2 2 2 0 HMG (high mobility group) box 5 AC_N PF16214.5 PSC76676.1 - 7.4 5.6 7.4 20 4.2 7.4 1.7 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Es2 PF09751.9 PSC76677.1 - 2e-67 228.8 0.0 2e-65 222.3 0.0 2.4 1 1 1 2 2 2 2 Nuclear protein Es2 Homoserine_dh PF00742.19 PSC76677.1 - 1.3e-56 191.3 0.0 3.2e-56 190.0 0.0 1.7 1 0 0 1 1 1 1 Homoserine dehydrogenase OSCP PF00213.18 PSC76677.1 - 1.9e-45 155.1 4.5 3.5e-45 154.2 4.5 1.5 1 0 0 1 1 1 1 ATP synthase delta (OSCP) subunit AA_kinase PF00696.28 PSC76677.1 - 5.3e-35 121.1 0.0 1.5e-34 119.7 0.0 1.8 2 0 0 2 2 2 1 Amino acid kinase family NAD_binding_3 PF03447.16 PSC76677.1 - 2.4e-20 73.4 0.0 1.1e-19 71.2 0.0 2.3 1 0 0 1 1 1 1 Homoserine dehydrogenase, NAD binding domain ACT PF01842.25 PSC76677.1 - 3.7e-19 68.2 0.8 3.4e-09 36.3 0.1 2.8 2 0 0 2 2 2 2 ACT domain ACT_7 PF13840.6 PSC76677.1 - 1.1e-16 60.4 2.7 7.1e-08 32.1 0.0 2.6 2 0 0 2 2 2 2 ACT domain Tudor-knot PF11717.8 PSC76677.1 - 0.05 13.5 0.0 1 9.3 0.0 2.5 2 0 0 2 2 2 0 RNA binding activity-knot of a chromodomain ACT_6 PF13740.6 PSC76677.1 - 0.1 12.6 0.4 2.2 8.3 0.1 2.9 3 0 0 3 3 3 0 ACT domain PIH1 PF08190.12 PSC76678.1 - 6.1e-22 77.9 0.0 1.1e-21 77.1 0.0 1.2 1 0 0 1 1 1 1 PIH1 N-terminal domain COX6A PF02046.15 PSC76680.1 - 1.8e-07 31.6 2.5 4e-07 30.5 2.5 1.5 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIa Complex1_LYR PF05347.15 PSC76680.1 - 0.13 12.3 0.8 0.2 11.8 0.8 1.3 1 0 0 1 1 1 0 Complex 1 protein (LYR family) DUF1804 PF08822.11 PSC76680.1 - 0.61 10.1 4.1 0.76 9.8 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1804) AAA PF00004.29 PSC76681.1 - 9.8e-35 119.9 0.0 1.5e-34 119.2 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 PSC76681.1 - 1.3e-07 31.3 0.0 3.1e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 PSC76681.1 - 8.9e-07 28.8 0.0 2.3e-06 27.5 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 PSC76681.1 - 2.5e-06 27.8 0.2 0.0029 17.9 0.1 3.0 1 1 2 3 3 2 1 AAA domain AAA_5 PF07728.14 PSC76681.1 - 1.9e-05 24.7 0.1 0.0005 20.1 0.1 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 PSC76681.1 - 2.6e-05 24.0 0.0 5e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 PSC76681.1 - 3.2e-05 24.5 0.0 6.9e-05 23.4 0.0 1.6 2 0 0 2 2 1 1 AAA domain AAA_16 PF13191.6 PSC76681.1 - 3.3e-05 24.3 1.9 0.00018 21.9 0.3 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.6 PSC76681.1 - 5.9e-05 23.3 0.0 0.00013 22.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 PSC76681.1 - 6.9e-05 22.3 0.1 0.19 11.2 0.0 2.5 2 1 1 3 3 3 2 Bacterial TniB protein ATPase PF06745.13 PSC76681.1 - 0.00042 19.7 0.0 0.12 11.7 0.0 2.2 1 1 1 2 2 2 1 KaiC AAA_7 PF12775.7 PSC76681.1 - 0.00043 19.8 0.1 0.001 18.6 0.0 1.6 2 0 0 2 2 1 1 P-loop containing dynein motor region TIP49 PF06068.13 PSC76681.1 - 0.00074 18.8 0.1 0.0019 17.4 0.0 1.6 1 1 1 2 2 2 1 TIP49 P-loop domain NACHT PF05729.12 PSC76681.1 - 0.00091 19.2 0.2 0.048 13.6 0.0 2.5 1 1 0 2 2 2 1 NACHT domain Mg_chelatase PF01078.21 PSC76681.1 - 0.00098 18.6 0.1 0.0022 17.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 PSC76681.1 - 0.0012 18.6 0.0 0.0024 17.6 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.14 PSC76681.1 - 0.0022 18.2 0.0 0.0038 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 PSC76681.1 - 0.0026 17.4 0.1 0.02 14.5 0.0 2.4 3 0 0 3 3 3 1 AAA domain Sigma54_activ_2 PF14532.6 PSC76681.1 - 0.0028 17.8 0.0 0.027 14.6 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain Parvo_NS1 PF01057.17 PSC76681.1 - 0.0035 16.5 0.0 0.0057 15.8 0.0 1.2 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RNA_helicase PF00910.22 PSC76681.1 - 0.0073 16.7 0.0 0.012 16.0 0.0 1.4 1 0 0 1 1 1 1 RNA helicase DUF815 PF05673.13 PSC76681.1 - 0.0085 15.3 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_14 PF13173.6 PSC76681.1 - 0.012 15.7 0.0 0.02 14.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 PSC76681.1 - 0.016 15.6 0.1 0.84 10.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 PSC76681.1 - 0.019 15.2 0.1 0.057 13.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.26 PSC76681.1 - 0.023 14.4 0.0 0.15 11.8 0.0 2.0 2 0 0 2 2 2 0 Sigma-54 interaction domain TsaE PF02367.17 PSC76681.1 - 0.023 14.7 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 PSC76681.1 - 0.03 13.8 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein Rad17 PF03215.15 PSC76681.1 - 0.038 13.9 0.1 0.21 11.5 0.1 2.0 1 1 1 2 2 2 0 Rad17 P-loop domain AAA_11 PF13086.6 PSC76681.1 - 0.062 13.1 0.0 0.11 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain Bac_DnaA PF00308.18 PSC76681.1 - 0.08 12.8 0.0 0.23 11.3 0.0 1.7 1 1 0 1 1 1 0 Bacterial dnaA protein AAA_6 PF12774.7 PSC76681.1 - 0.12 11.4 0.0 0.21 10.5 0.0 1.3 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region IPT PF01745.16 PSC76681.1 - 0.13 11.7 0.0 1.7 8.0 0.0 2.1 2 0 0 2 2 2 0 Isopentenyl transferase AAA_3 PF07726.11 PSC76681.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.27 PSC76681.1 - 0.14 12.7 0.0 0.25 11.9 0.0 1.5 1 0 0 1 1 1 0 ABC transporter Pkinase_Tyr PF07714.17 PSC76682.1 - 8.5e-84 280.9 0.0 2.2e-37 128.8 0.0 3.5 3 1 0 3 3 3 3 Protein tyrosine kinase Pkinase PF00069.25 PSC76682.1 - 9.7e-75 251.3 0.0 8.2e-32 110.6 0.0 4.1 4 0 0 4 4 4 4 Protein kinase domain Kdo PF06293.14 PSC76682.1 - 2.5e-05 23.8 0.0 0.24 10.7 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2561 PF10812.8 PSC76682.1 - 0.0023 18.0 3.8 0.0023 18.0 3.8 3.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2561) PHD_4 PF16866.5 PSC76682.1 - 0.12 12.4 0.0 20 5.4 0.0 2.4 2 0 0 2 2 2 0 PHD-finger Kinase-like PF14531.6 PSC76682.1 - 0.24 10.7 0.0 13 4.9 0.0 2.2 2 0 0 2 2 2 0 Kinase-like DUF1098 PF06497.11 PSC76682.1 - 1.5 9.3 3.3 1.2 9.7 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1098) Phage_holin_3_6 PF07332.11 PSC76682.1 - 1.8 8.6 10.8 3.6 7.7 0.6 3.0 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DnaJ_CXXCXGXG PF00684.19 PSC76683.1 - 1.3e-05 25.5 0.3 0.0065 16.8 0.2 2.4 2 0 0 2 2 2 2 DnaJ central domain DUF1356 PF07092.12 PSC76683.1 - 0.0056 16.0 0.1 2.3 7.4 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1356) DUF1178 PF06676.11 PSC76683.1 - 0.026 14.9 0.1 9.2 6.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1178) zf-Mss51 PF13824.6 PSC76683.1 - 0.23 11.6 1.9 0.25 11.5 0.1 1.9 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Lar_restr_allev PF14354.6 PSC76683.1 - 0.25 11.7 0.1 0.25 11.7 0.1 3.1 3 1 0 3 3 3 0 Restriction alleviation protein Lar Zn_Tnp_IS1 PF03811.13 PSC76683.1 - 0.26 11.1 7.4 1.9 8.3 0.2 2.9 2 1 0 2 2 2 0 InsA N-terminal domain zf-TFIIB PF13453.6 PSC76683.1 - 0.99 8.8 8.1 27 4.2 0.1 3.5 3 0 0 3 3 3 0 Transcription factor zinc-finger zf_Rg PF17915.1 PSC76683.1 - 1 8.8 4.1 5.4 6.5 0.1 2.7 3 0 0 3 3 3 0 Reverse gyrase zinc finger Zn-ribbon_8 PF09723.10 PSC76683.1 - 1.6 8.9 0.0 1.6 8.9 0.0 3.1 3 1 0 3 3 3 0 Zinc ribbon domain Anti-TRAP PF15777.5 PSC76683.1 - 3 7.9 8.0 38 4.4 0.1 2.9 2 1 0 2 2 2 0 Tryptophan RNA-binding attenuator protein inhibitory protein RMI1_N PF08585.12 PSC76684.1 - 1.1e-17 64.6 0.1 2.1e-13 50.6 0.0 2.3 2 0 0 2 2 2 2 RecQ mediated genome instability protein RMI1_N PF08585.12 PSC76685.1 - 9.7e-18 64.7 0.0 2.1e-13 50.5 0.0 2.3 2 0 0 2 2 2 2 RecQ mediated genome instability protein Nuc_sug_transp PF04142.15 PSC76686.1 - 6.9e-08 32.0 4.5 1.8e-07 30.7 0.5 2.1 2 0 0 2 2 2 1 Nucleotide-sugar transporter EamA PF00892.20 PSC76686.1 - 3.7e-07 30.4 1.3 3.7e-07 30.4 1.3 3.7 3 1 0 4 4 4 2 EamA-like transporter family PUNUT PF16913.5 PSC76686.1 - 0.0072 15.6 4.5 0.011 15.0 3.0 2.1 2 1 0 2 2 2 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 PSC76686.1 - 0.13 11.1 14.1 0.016 14.1 4.3 2.1 2 0 0 2 2 2 0 CRT-like, chloroquine-resistance transporter-like RFX1_trans_act PF04589.13 PSC76686.1 - 0.91 9.7 4.8 1.9 8.6 4.8 1.5 1 0 0 1 1 1 0 RFX1 transcription activation region TPT PF03151.16 PSC76686.1 - 5.6 6.2 9.7 0.15 11.4 1.2 2.3 2 1 0 2 2 2 0 Triose-phosphate Transporter family PP2C PF00481.21 PSC76687.1 - 1e-25 90.9 0.0 2.2e-25 89.8 0.0 1.5 1 0 0 1 1 1 1 Protein phosphatase 2C Acetyltransf_1 PF00583.25 PSC76688.1 - 1.2e-12 48.1 0.0 2.2e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PSC76688.1 - 1.6e-08 34.5 0.0 3.4e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC76688.1 - 7e-08 32.3 0.0 2.2e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_7 PF13508.7 PSC76688.1 - 1.6e-06 28.5 0.0 3.2e-06 27.5 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain PanZ PF12568.8 PSC76688.1 - 0.0034 17.1 1.0 0.0082 15.9 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_9 PF13527.7 PSC76688.1 - 0.004 17.2 0.6 0.073 13.2 0.0 2.9 4 0 0 4 4 4 1 Acetyltransferase (GNAT) domain Phage_GPD PF05954.11 PSC76689.1 - 0.92 8.7 12.8 1.2 8.3 12.8 1.1 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) DUF2397 PF09660.10 PSC76689.1 - 1.9 7.3 21.7 2.2 7.1 21.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2397) eIF3_subunit PF08597.10 PSC76689.1 - 5.1 6.9 9.3 6.8 6.5 9.3 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Glutaredoxin PF00462.24 PSC76690.1 - 1.1e-15 57.6 0.0 1.9e-15 56.8 0.0 1.4 1 0 0 1 1 1 1 Glutaredoxin GIY-YIG PF01541.24 PSC76690.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 GIY-YIG catalytic domain rve PF00665.26 PSC76691.1 - 1.1e-18 67.6 0.0 2.6e-18 66.4 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC76691.1 - 0.007 16.1 0.0 0.025 14.3 0.0 1.9 1 0 0 1 1 1 1 Integrase core domain PIP5K PF01504.18 PSC76693.1 - 1.5e-70 237.6 0.0 1.5e-56 191.6 0.0 2.4 2 1 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase MORN PF02493.20 PSC76693.1 - 4e-08 32.7 24.4 7e-05 22.5 3.2 4.0 3 0 0 3 3 3 3 MORN repeat Rotamase_3 PF13616.6 PSC76693.1 - 0.05 14.2 0.2 0.13 12.9 0.2 1.6 1 0 0 1 1 1 0 PPIC-type PPIASE domain Ribosomal_60s PF00428.19 PSC76694.1 - 2.3e-22 79.4 10.5 2.7e-22 79.2 10.5 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Peptidase_M17_N PF02789.17 PSC76694.1 - 0.015 15.2 0.8 0.015 15.2 0.8 1.4 2 0 0 2 2 2 0 Cytosol aminopeptidase family, N-terminal domain Barwin PF00967.17 PSC76695.1 - 3.9e-31 107.4 0.5 4.8e-31 107.1 0.5 1.0 1 0 0 1 1 1 1 Barwin family Transposase_21 PF02992.14 PSC76697.1 - 1.9e-09 37.1 0.0 2.8e-09 36.5 0.0 1.2 1 0 0 1 1 1 1 Transposase family tnp2 DUF4218 PF13960.6 PSC76697.1 - 0.004 16.7 0.0 0.0075 15.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4218) RcbX PF02341.15 PSC76698.1 - 8.8e-15 54.9 0.0 1.1e-14 54.6 0.0 1.0 1 0 0 1 1 1 1 RbcX protein PHC2_SAM_assoc PF16616.5 PSC76699.1 - 0.009 16.8 0.0 0.01 16.6 0.0 1.2 1 0 0 1 1 1 1 Unstructured region on Polyhomeotic-like protein 1 and 2 Pterin_4a PF01329.19 PSC76700.1 - 2.7e-24 85.1 0.3 4.1e-24 84.6 0.3 1.3 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase LID PF17916.1 PSC76700.1 - 0.048 13.3 0.1 0.34 10.6 0.0 2.1 2 0 0 2 2 2 0 LIM interaction domain (LID) Snf7 PF03357.21 PSC76701.1 - 5.9e-28 97.6 4.1 5.4e-27 94.5 5.3 1.8 2 0 0 2 2 2 1 Snf7 Peptidase_M11 PF05548.11 PSC76701.1 - 3.6e-15 55.9 0.0 5.3e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Gametolysin peptidase M11 Peptidase_M66 PF10462.9 PSC76701.1 - 4.2 6.2 8.4 0.16 10.9 1.5 1.8 2 0 0 2 2 2 0 Peptidase M66 RNase_T PF00929.24 PSC76702.1 - 8.9e-14 52.4 0.0 1.4e-13 51.7 0.0 1.3 1 0 0 1 1 1 1 Exonuclease Ndc1_Nup PF09531.10 PSC76702.1 - 1.8 7.2 2.6 2 7.0 2.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CENP-U PF13097.6 PSC76702.1 - 7.6 6.5 9.2 0.81 9.6 5.0 1.5 2 0 0 2 2 2 0 CENP-A nucleosome associated complex (NAC) subunit CAP59_mtransfer PF11735.8 PSC76703.1 - 4.5e-09 36.3 0.0 7e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Cryptococcal mannosyltransferase 1 LRR_6 PF13516.6 PSC76703.1 - 1.1e-05 25.0 6.6 0.81 9.9 0.0 6.7 6 1 1 7 7 7 2 Leucine Rich repeat F-box-like PF12937.7 PSC76703.1 - 8.2e-05 22.4 1.8 0.00018 21.4 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PSC76703.1 - 0.0019 18.0 2.0 0.0026 17.6 0.0 2.2 2 0 0 2 2 2 1 F-box domain LRR_1 PF00560.33 PSC76703.1 - 0.0024 18.2 7.6 6.5 7.7 0.1 6.8 8 0 0 8 8 8 1 Leucine Rich Repeat Barwin PF00967.17 PSC76703.1 - 0.0052 16.6 1.0 0.021 14.7 0.2 2.3 2 0 0 2 2 2 1 Barwin family Glyco_tranf_2_4 PF13704.6 PSC76703.1 - 0.0053 17.2 1.0 0.011 16.2 0.2 2.0 2 0 0 2 2 2 1 Glycosyl transferase family 2 DPBB_1 PF03330.18 PSC76703.1 - 0.068 13.5 0.0 0.22 11.8 0.0 1.9 1 0 0 1 1 1 0 Lytic transglycolase Exostosin PF03016.15 PSC76704.1 - 4.2e-46 157.5 0.6 8.2e-46 156.6 0.6 1.5 1 1 0 1 1 1 1 Exostosin family Pkinase PF00069.25 PSC76704.1 - 2.9e-36 125.2 0.0 5.7e-36 124.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC76704.1 - 1.2e-30 106.7 0.0 4.1e-30 104.9 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase SET PF00856.28 PSC76704.1 - 1.8e-10 41.4 0.1 1e-09 39.0 0.0 2.2 2 0 0 2 2 2 1 SET domain LRR_8 PF13855.6 PSC76704.1 - 1.4e-09 37.6 0.0 6e-07 29.1 0.0 3.4 3 0 0 3 3 3 1 Leucine rich repeat LRR_4 PF12799.7 PSC76704.1 - 6.5e-06 26.4 0.2 0.00015 22.1 0.2 3.3 3 1 1 4 4 4 2 Leucine Rich repeats (2 copies) EGF_2 PF07974.13 PSC76704.1 - 0.0014 18.9 14.1 0.0014 18.9 14.1 4.0 3 0 0 3 3 3 1 EGF-like domain TPR_12 PF13424.6 PSC76704.1 - 0.002 18.4 26.1 0.036 14.4 7.1 4.5 3 0 0 3 3 3 2 Tetratricopeptide repeat zf-MYND PF01753.18 PSC76704.1 - 0.0053 16.8 3.3 0.033 14.3 3.3 2.5 1 0 0 1 1 1 1 MYND finger LRR_1 PF00560.33 PSC76704.1 - 0.027 15.0 0.0 13 6.8 0.1 3.2 2 0 0 2 2 2 0 Leucine Rich Repeat EGF_Tenascin PF18720.1 PSC76704.1 - 0.088 12.9 3.7 0.28 11.3 3.7 2.0 1 0 0 1 1 1 0 Tenascin EGF domain Kdo PF06293.14 PSC76704.1 - 0.096 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Exostosin PF03016.15 PSC76705.1 - 3e-47 161.3 0.5 9.9e-47 159.6 0.5 1.8 1 1 0 1 1 1 1 Exostosin family EGF_2 PF07974.13 PSC76705.1 - 5.9e-08 32.9 52.7 0.00014 22.2 8.9 4.5 4 0 0 4 4 4 3 EGF-like domain Pkinase PF00069.25 PSC76706.1 - 1.8e-36 125.9 0.0 3.7e-36 124.9 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC76706.1 - 6.2e-31 107.6 0.0 2.7e-30 105.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase SET PF00856.28 PSC76706.1 - 8.3e-11 42.6 0.0 6.4e-10 39.7 0.0 2.4 2 0 0 2 2 2 1 SET domain LRR_8 PF13855.6 PSC76706.1 - 4.4e-10 39.2 0.0 4.2e-07 29.6 0.0 3.7 4 0 0 4 4 4 1 Leucine rich repeat LRR_4 PF12799.7 PSC76706.1 - 1.9e-06 28.1 0.0 0.0001 22.6 0.2 3.6 4 1 1 5 5 5 2 Leucine Rich repeats (2 copies) zf-MYND PF01753.18 PSC76706.1 - 0.0044 17.1 3.3 0.023 14.8 3.3 2.3 1 0 0 1 1 1 1 MYND finger LRR_1 PF00560.33 PSC76706.1 - 0.012 16.0 0.0 8.9 7.3 0.1 3.3 2 0 0 2 2 2 0 Leucine Rich Repeat Kdo PF06293.14 PSC76706.1 - 0.066 12.6 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_12 PF13424.6 PSC76706.1 - 0.5 10.7 35.7 0.025 14.9 7.1 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Mito_fiss_reg PF05308.11 PSC76708.1 - 0.2 11.7 0.8 0.24 11.4 0.8 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator CAP_N PF01213.19 PSC76708.1 - 0.22 11.0 2.6 0.29 10.6 2.6 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal PRIMA1 PF16101.5 PSC76709.1 - 0.4 10.7 5.1 0.14 12.2 1.0 2.1 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 Mito_fiss_reg PF05308.11 PSC76709.1 - 3.6 7.6 4.0 0.8 9.7 0.8 1.5 2 0 0 2 2 2 0 Mitochondrial fission regulator ABC1 PF03109.16 PSC76710.1 - 1.7e-30 105.6 0.0 3.3e-30 104.7 0.0 1.5 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 PSC76710.1 - 0.00011 21.6 0.0 0.051 12.9 0.0 2.2 2 0 0 2 2 2 2 Protein kinase domain WaaY PF06176.11 PSC76710.1 - 0.018 14.7 0.0 0.041 13.5 0.0 1.6 1 0 0 1 1 1 0 Lipopolysaccharide core biosynthesis protein (WaaY) APH PF01636.23 PSC76710.1 - 0.024 14.6 0.1 0.024 14.6 0.1 3.7 4 1 0 4 4 4 0 Phosphotransferase enzyme family LapA_dom PF06305.11 PSC76710.1 - 0.12 12.2 0.8 0.26 11.1 0.8 1.6 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain DUF179 PF02622.15 PSC76711.1 - 6.9e-27 94.4 0.0 1.3e-26 93.4 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 GSDH PF07995.11 PSC76711.1 - 0.00014 21.3 0.0 0.00032 20.1 0.0 1.5 1 0 0 1 1 1 1 Glucose / Sorbosone dehydrogenase Cullin PF00888.22 PSC76712.1 - 1e-167 559.5 16.0 1e-167 559.5 16.0 1.5 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 PSC76712.1 - 4.7e-27 93.8 4.0 4.7e-27 93.8 4.0 2.1 2 0 0 2 2 2 1 Cullin protein neddylation domain DUF1803 PF08820.10 PSC76712.1 - 0.015 15.3 3.5 4.3 7.4 0.5 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1803) BLOC1S3 PF15753.5 PSC76712.1 - 0.34 11.0 4.1 0.77 9.9 1.3 2.4 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex 1 subunit 3 Adaptin_binding PF10199.9 PSC76712.1 - 1.6 9.4 5.2 6.2 7.5 2.9 2.8 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 RIBIOP_C PF04950.12 PSC76713.1 - 1.8e-79 267.2 0.9 3.9e-79 266.1 0.0 1.9 2 0 0 2 2 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 PSC76713.1 - 6.2e-30 103.1 0.0 3.8e-29 100.6 0.0 2.3 2 0 0 2 2 2 1 AARP2CN (NUC121) domain AAA PF00004.29 PSC76713.1 - 8.6e-06 26.2 0.0 1.7e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 PSC76713.1 - 2.2e-05 24.9 0.1 0.00023 21.6 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 PSC76713.1 - 0.00073 19.8 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 PSC76713.1 - 0.0029 18.0 0.1 0.0065 16.8 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 PSC76713.1 - 0.0033 17.6 2.4 0.014 15.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.27 PSC76713.1 - 0.0046 16.5 0.0 0.067 12.7 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 PSC76713.1 - 0.0081 16.7 0.0 0.032 14.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 PSC76713.1 - 0.013 15.4 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 NACHT domain NTPase_1 PF03266.15 PSC76713.1 - 0.015 15.2 0.2 0.03 14.2 0.2 1.5 1 0 0 1 1 1 0 NTPase Viral_helicase1 PF01443.18 PSC76713.1 - 0.021 14.6 0.1 0.04 13.6 0.1 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_11 PF13086.6 PSC76713.1 - 0.023 14.5 0.2 0.023 14.5 0.2 3.5 4 1 0 4 4 4 0 AAA domain RuvB_N PF05496.12 PSC76713.1 - 0.041 13.6 0.0 0.073 12.8 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain NB-ARC PF00931.22 PSC76713.1 - 0.047 12.9 0.0 0.078 12.1 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain RNA_helicase PF00910.22 PSC76713.1 - 0.047 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 RNA helicase TsaE PF02367.17 PSC76713.1 - 0.049 13.6 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 PSC76713.1 - 0.073 13.0 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 Rad17 P-loop domain ATPase_2 PF01637.18 PSC76713.1 - 0.074 13.0 0.0 0.17 11.8 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Septin PF00735.18 PSC76713.1 - 0.089 12.1 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Septin AAA_14 PF13173.6 PSC76713.1 - 0.089 12.8 0.0 0.3 11.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 PSC76713.1 - 0.18 11.9 0.0 0.5 10.5 0.0 1.8 1 1 0 1 1 1 0 50S ribosome-binding GTPase cobW PF02492.19 PSC76713.1 - 0.2 11.2 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 PSC76713.1 - 0.27 11.0 0.0 0.49 10.1 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein Pkinase_Tyr PF07714.17 PSC76714.1 - 1e-47 162.6 0.0 4.1e-47 160.7 0.0 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC76714.1 - 4.9e-45 153.9 0.0 1.5e-44 152.4 0.0 1.6 1 1 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 PSC76714.1 - 0.074 12.3 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 PSC76714.1 - 0.11 11.8 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Rubis-subs-bind PF09273.11 PSC76715.1 - 1.8e-05 25.4 7.2 6.2e-05 23.7 7.2 1.9 1 1 0 1 1 1 1 Rubisco LSMT substrate-binding POM121 PF15229.6 PSC76715.1 - 0.0052 16.5 2.0 0.0052 16.5 2.0 1.5 2 0 0 2 2 2 1 POM121 family SET PF00856.28 PSC76715.1 - 0.045 14.1 0.5 0.34 11.3 0.0 2.2 2 0 0 2 2 2 0 SET domain DUF4281 PF14108.6 PSC76716.1 - 3.7e-28 98.4 5.9 5.4e-28 97.9 5.9 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) DUF4281 PF14108.6 PSC76717.1 - 3.2e-34 118.0 10.6 4.9e-34 117.4 10.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4281) Myb_DNA-binding PF00249.31 PSC76718.1 - 1.6e-09 37.8 0.1 4e-09 36.5 0.1 1.7 1 1 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 PSC76718.1 - 0.00093 19.4 0.0 0.0016 18.6 0.0 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_5 PF13873.6 PSC76718.1 - 0.28 11.3 0.5 0.69 10.0 0.2 1.7 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Aminotran_1_2 PF00155.21 PSC76719.1 - 1.2e-29 103.6 0.0 1.8e-29 103.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 PSC76719.1 - 4.1e-05 22.5 0.0 0.00023 20.1 0.0 2.2 1 1 0 1 1 1 1 Alanine-glyoxylate amino-transferase Alliinase_C PF04864.13 PSC76719.1 - 6.2e-05 22.0 0.0 7.7e-05 21.7 0.0 1.2 1 0 0 1 1 1 1 Allinase Aminotran_5 PF00266.19 PSC76719.1 - 0.016 14.2 0.0 0.025 13.6 0.0 1.2 1 0 0 1 1 1 0 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 PSC76719.1 - 0.1 11.1 0.0 0.14 10.7 0.0 1.1 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme DUF819 PF05684.12 PSC76721.1 - 1.2e-73 248.4 16.2 1.5e-73 248.1 16.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF819) DUF819 PF05684.12 PSC76722.1 - 3.7e-56 190.8 19.4 4.2e-56 190.6 19.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF819) Fasciclin PF02469.22 PSC76723.1 - 2.1e-18 66.8 0.4 2.8e-18 66.4 0.4 1.2 1 0 0 1 1 1 1 Fasciclin domain Cpn60_TCP1 PF00118.24 PSC76724.1 - 2.9e-163 544.0 0.4 3.3e-163 543.9 0.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Trypan_PARP PF05887.11 PSC76725.1 - 0.0043 17.0 12.6 0.012 15.6 12.6 1.7 1 0 0 1 1 1 1 Procyclic acidic repetitive protein (PARP) MIEAP PF16026.5 PSC76725.1 - 0.24 11.6 0.0 0.39 10.9 0.0 1.2 1 0 0 1 1 1 0 Mitochondria-eating protein SIR2 PF02146.17 PSC76726.1 - 8.7e-41 139.8 0.0 6e-40 137.1 0.0 2.0 1 1 0 1 1 1 1 Sir2 family FIST PF08495.10 PSC76726.1 - 3.8e-07 30.3 0.3 1.9e-06 28.0 0.1 2.4 2 0 0 2 2 2 1 FIST N domain FIST_C PF10442.9 PSC76726.1 - 4.2e-06 26.8 0.1 1.6e-05 24.9 0.1 2.1 1 1 0 1 1 1 1 FIST C domain C2 PF00168.30 PSC76727.1 - 1.2e-21 77.0 0.0 7.1e-18 64.8 0.0 3.0 3 0 0 3 3 3 2 C2 domain SMP_LBD PF17047.5 PSC76727.1 - 3.9e-06 26.5 0.0 0.0018 17.8 0.0 2.5 1 1 1 2 2 2 1 Synaptotagmin-like mitochondrial-lipid-binding domain DIM PF08194.12 PSC76728.1 - 0.48 10.7 2.4 0.96 9.7 2.4 1.5 1 0 0 1 1 1 0 DIM protein Trypsin_2 PF13365.6 PSC76730.1 - 2.2e-21 77.3 21.8 1.4e-19 71.5 2.6 3.8 4 1 0 4 4 4 2 Trypsin-like peptidase domain U-box PF04564.15 PSC76731.1 - 5.9e-26 90.4 0.1 1e-25 89.7 0.1 1.4 1 0 0 1 1 1 1 U-box domain SPRY PF00622.28 PSC76731.1 - 2.1e-20 73.0 0.1 3.7e-20 72.2 0.1 1.4 1 0 0 1 1 1 1 SPRY domain Ufd2P_core PF10408.9 PSC76731.1 - 0.0002 20.1 0.0 0.0002 20.1 0.0 2.6 3 0 0 3 3 3 1 Ubiquitin elongating factor core His_biosynth PF00977.21 PSC76732.1 - 2.7e-47 161.1 0.1 1e-46 159.2 0.1 2.0 1 1 0 1 1 1 1 Histidine biosynthesis protein GATase PF00117.28 PSC76732.1 - 1.2e-19 70.8 0.0 1.9e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I SNO PF01174.19 PSC76732.1 - 5.8e-09 36.1 0.0 1.3e-05 25.2 0.0 2.4 2 0 0 2 2 2 2 SNO glutamine amidotransferase family GATase_3 PF07685.14 PSC76732.1 - 2.9e-06 27.0 0.1 6e-06 26.0 0.1 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain ThiG PF05690.14 PSC76732.1 - 0.071 12.4 0.4 0.21 10.8 0.4 1.7 2 0 0 2 2 2 0 Thiazole biosynthesis protein ThiG GATase_5 PF13507.6 PSC76732.1 - 0.18 10.8 0.0 0.34 10.0 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain FAP PF07174.11 PSC76733.1 - 3.3 7.1 15.9 3.6 6.9 15.9 1.0 1 0 0 1 1 1 0 Fibronectin-attachment protein (FAP) RVT_2 PF07727.14 PSC76734.1 - 3.1e-74 249.7 0.0 3.9e-74 249.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Crr6 PF08847.11 PSC76734.1 - 0.079 12.6 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Chlororespiratory reduction 6 RNase_T PF00929.24 PSC76736.1 - 0.0064 17.0 0.0 0.0079 16.7 0.0 1.1 1 0 0 1 1 1 1 Exonuclease DSPc PF00782.20 PSC76737.1 - 0.015 15.1 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 PSC76737.1 - 0.12 12.0 0.2 0.19 11.4 0.2 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 PSC76737.1 - 0.2 11.2 0.2 0.32 10.5 0.2 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Methyltrans_RNA PF04452.14 PSC76737.1 - 0.2 10.9 0.0 0.4 10.0 0.0 1.4 1 0 0 1 1 1 0 RNA methyltransferase Y_phosphatase3 PF13350.6 PSC76737.1 - 0.23 11.4 0.0 0.36 10.8 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family TFIIA PF03153.13 PSC76737.1 - 9.7 6.1 8.4 12 5.7 8.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ATP-synt_B PF00430.18 PSC76738.1 - 1.9e-17 63.6 4.5 1.9e-17 63.6 4.5 2.4 2 0 0 2 2 2 1 ATP synthase B/B' CF(0) XPA_C PF05181.12 PSC76738.1 - 1.6e-07 31.2 0.0 2.6e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 XPA protein C-terminus F-box-like PF12937.7 PSC76738.1 - 1.1e-06 28.4 1.2 1.9e-06 27.6 0.5 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PSC76738.1 - 2.7e-05 23.9 0.0 5.6e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 F-box domain Phasin PF05597.11 PSC76738.1 - 0.0074 16.3 5.8 0.016 15.2 5.8 1.5 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) F-box_4 PF15966.5 PSC76738.1 - 0.04 13.8 0.0 0.079 12.8 0.0 1.4 1 0 0 1 1 1 0 F-box Spt20 PF12090.8 PSC76738.1 - 0.066 12.8 1.4 0.46 10.1 3.2 1.4 2 0 0 2 2 2 0 Spt20 family Phage_GP20 PF06810.11 PSC76738.1 - 0.1 12.4 11.1 0.21 11.4 11.1 1.4 1 0 0 1 1 1 0 Phage minor structural protein GP20 YlqD PF11068.8 PSC76738.1 - 0.33 11.3 9.5 0.081 13.3 1.6 2.2 2 0 0 2 2 2 0 YlqD protein Synaptobrevin PF00957.21 PSC76739.1 - 4.6e-08 32.7 0.6 8.2e-08 31.9 0.6 1.3 1 0 0 1 1 1 1 Synaptobrevin ANAPC4_WD40 PF12894.7 PSC76739.1 - 0.00015 22.0 0.0 1.6 9.1 0.0 4.2 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PSC76739.1 - 0.0009 20.0 0.0 1 10.4 0.0 5.0 5 0 0 5 5 5 1 WD domain, G-beta repeat Utp14 PF04615.13 PSC76740.1 - 3.2e-160 535.3 50.8 3.2e-160 535.3 50.8 2.9 2 1 0 2 2 2 1 Utp14 protein Utp14 PF04615.13 PSC76741.1 - 5.2e-158 527.9 52.3 4.5e-107 359.5 30.9 2.9 2 1 1 3 3 3 2 Utp14 protein Pex2_Pex12 PF04757.14 PSC76742.1 - 9.5e-32 110.4 0.4 1.2e-31 110.1 0.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 PSC76742.1 - 1.8e-05 25.0 9.5 2.7e-05 24.4 9.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 PSC76742.1 - 3.2e-05 23.7 9.2 4.9e-05 23.1 9.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 PSC76742.1 - 4.4e-05 23.3 7.9 6.1e-05 22.8 7.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PSC76742.1 - 0.0003 20.6 10.6 0.00047 20.0 10.6 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 PSC76742.1 - 0.00038 20.3 10.5 0.00058 19.7 10.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC76742.1 - 0.0046 17.0 10.2 0.0088 16.1 10.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PSC76742.1 - 0.015 15.4 12.9 0.023 14.8 12.9 1.3 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Pellino PF04710.14 PSC76742.1 - 0.1 11.3 0.7 0.14 10.8 0.7 1.1 1 0 0 1 1 1 0 Pellino zf-rbx1 PF12678.7 PSC76742.1 - 0.14 12.5 6.3 0.27 11.6 6.3 1.4 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_5 PF14634.6 PSC76742.1 - 0.19 11.7 10.6 0.44 10.5 10.6 1.6 1 1 1 2 2 2 0 zinc-RING finger domain Mito_carr PF00153.27 PSC76743.1 - 1.4e-44 149.9 11.0 4.2e-16 58.6 4.0 3.5 3 1 0 3 3 3 3 Mitochondrial carrier protein Pkinase PF00069.25 PSC76744.1 - 5.7e-53 180.0 0.0 9.7e-46 156.3 0.0 2.1 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC76744.1 - 1.6e-24 86.6 0.0 1.1e-22 80.5 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase cNMP_binding PF00027.29 PSC76744.1 - 9.3e-09 35.2 0.0 0.00045 20.2 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Kinase-like PF14531.6 PSC76744.1 - 8.6e-05 22.0 0.0 0.00013 21.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PSC76744.1 - 0.0075 15.6 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 PSC76744.1 - 0.012 15.5 0.0 0.012 15.5 0.0 3.3 3 2 1 4 4 4 0 Phosphotransferase enzyme family RIO1 PF01163.22 PSC76744.1 - 0.022 14.3 0.0 0.047 13.3 0.0 1.4 1 0 0 1 1 1 0 RIO1 family FTA2 PF13095.6 PSC76744.1 - 0.059 13.0 0.0 5.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Peptidase_M17 PF00883.21 PSC76745.1 - 2.6e-113 378.4 5.9 4.2e-113 377.7 5.9 1.3 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 PSC76745.1 - 1.6e-14 53.8 2.9 1.6e-14 53.8 2.9 3.2 3 0 0 3 3 3 1 Cytosol aminopeptidase family, N-terminal domain PDZ_6 PF17820.1 PSC76745.1 - 0.0025 17.6 0.2 0.032 14.1 0.1 2.5 2 0 0 2 2 2 1 PDZ domain UreE_N PF02814.15 PSC76745.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain Peptidase_M17 PF00883.21 PSC76746.1 - 2.6e-113 378.4 5.9 4.1e-113 377.8 5.9 1.3 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 PSC76746.1 - 1.6e-14 53.8 2.9 1.6e-14 53.8 2.9 3.3 3 0 0 3 3 3 1 Cytosol aminopeptidase family, N-terminal domain PDZ_6 PF17820.1 PSC76746.1 - 0.0024 17.7 0.2 0.032 14.1 0.1 2.5 2 0 0 2 2 2 1 PDZ domain UreE_N PF02814.15 PSC76746.1 - 0.11 12.1 0.0 0.29 10.8 0.0 1.7 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain Pkinase_Tyr PF07714.17 PSC76747.1 - 1.9e-49 168.3 0.0 2.8e-49 167.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC76747.1 - 2.6e-41 141.7 0.0 3.6e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain LRR_8 PF13855.6 PSC76747.1 - 5.3e-09 35.7 0.2 0.00032 20.4 0.0 2.6 2 0 0 2 2 2 2 Leucine rich repeat LRR_4 PF12799.7 PSC76747.1 - 1.7e-06 28.3 1.7 0.056 13.9 0.1 3.2 2 2 2 4 4 4 4 Leucine Rich repeats (2 copies) Haspin_kinase PF12330.8 PSC76747.1 - 0.00079 18.5 0.0 0.0017 17.4 0.0 1.4 1 1 0 1 1 1 1 Haspin like kinase domain LRRNT_2 PF08263.12 PSC76747.1 - 0.0015 18.8 0.8 0.0052 17.1 0.8 2.0 1 0 0 1 1 1 1 Leucine rich repeat N-terminal domain LRR_6 PF13516.6 PSC76747.1 - 0.0032 17.4 1.1 0.3 11.2 0.1 3.8 4 0 0 4 4 4 1 Leucine Rich repeat LRR_1 PF00560.33 PSC76747.1 - 0.0042 17.4 0.1 2.3 9.1 0.0 4.0 4 1 0 4 4 3 1 Leucine Rich Repeat Kinase-like PF14531.6 PSC76747.1 - 0.085 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Imm17 PF15562.6 PSC76747.1 - 0.14 12.1 0.2 0.33 10.9 0.2 1.6 1 0 0 1 1 1 0 Immunity protein 17 APH PF01636.23 PSC76747.1 - 0.42 10.5 0.0 0.42 10.5 0.0 2.4 3 0 0 3 3 3 0 Phosphotransferase enzyme family Amino_oxidase PF01593.24 PSC76748.1 - 3.6e-43 148.5 0.0 4.7e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 PSC76748.1 - 3.6e-06 27.1 0.0 3.6e-06 27.1 0.0 2.3 3 0 0 3 3 3 1 NAD(P)-binding Rossmann-like domain Beach PF02138.18 PSC76749.1 - 2.4e-112 374.8 0.0 3.4e-112 374.3 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain p450 PF00067.22 PSC76749.1 - 2.4e-71 240.9 0.0 7.4e-71 239.3 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 DUF4704 PF15787.5 PSC76749.1 - 6.1e-25 88.0 0.0 5.8e-24 84.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 PSC76749.1 - 6.9e-17 61.4 0.0 1.4e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 PSC76749.1 - 6.9e-10 38.6 1.1 1.3e-09 37.7 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) WD40 PF00400.32 PSC76749.1 - 4.3e-09 36.8 3.3 0.0026 18.6 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Laminin_G_3 PF13385.6 PSC76749.1 - 1.8e-07 31.4 0.0 2.1e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF1088 PF06469.11 PSC76749.1 - 0.0033 17.1 0.9 0.008 15.9 0.9 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) SUIM_assoc PF16619.5 PSC76749.1 - 0.028 14.5 5.0 0.029 14.4 1.9 2.7 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Arm PF00514.23 PSC76749.1 - 0.73 10.0 5.3 1.7 8.8 0.3 3.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Beach PF02138.18 PSC76750.1 - 2.4e-112 374.8 0.0 3.4e-112 374.3 0.0 1.2 1 0 0 1 1 1 1 Beige/BEACH domain p450 PF00067.22 PSC76750.1 - 2.4e-71 240.9 0.0 7.4e-71 239.3 0.0 1.7 1 1 0 1 1 1 1 Cytochrome P450 DUF4704 PF15787.5 PSC76750.1 - 6.1e-25 88.0 0.0 5.8e-24 84.8 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 PSC76750.1 - 6.9e-17 61.4 0.0 1.4e-16 60.4 0.0 1.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH DUF4800 PF16057.5 PSC76750.1 - 6.8e-10 38.6 1.1 1.3e-09 37.7 1.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4800) WD40 PF00400.32 PSC76750.1 - 4.4e-09 36.8 3.3 0.0026 18.6 0.0 4.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Laminin_G_3 PF13385.6 PSC76750.1 - 1.8e-07 31.4 0.0 2.1e-05 24.7 0.0 2.5 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF1088 PF06469.11 PSC76750.1 - 0.0033 17.1 0.9 0.008 15.9 0.9 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) SUIM_assoc PF16619.5 PSC76750.1 - 0.026 14.6 5.0 0.029 14.4 1.9 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Arm PF00514.23 PSC76750.1 - 0.73 10.0 5.3 1.7 8.8 0.3 3.9 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat DUF1929 PF09118.11 PSC76751.1 - 9.6e-18 64.3 0.2 1.7e-17 63.5 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1929) Glyoxal_oxid_N PF07250.11 PSC76751.1 - 1e-10 41.2 0.0 5.2e-05 22.6 0.1 2.3 2 0 0 2 2 2 2 Glyoxal oxidase N-terminus Kelch_6 PF13964.6 PSC76751.1 - 7.4e-07 29.2 5.8 0.52 10.7 0.0 5.8 4 1 1 5 5 5 1 Kelch motif DUF2384 PF09722.10 PSC76751.1 - 0.0018 18.3 0.0 0.0049 16.9 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2384) AZUL PF16558.5 PSC76751.1 - 0.0018 18.4 0.0 0.0035 17.6 0.0 1.4 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Kelch_1 PF01344.25 PSC76751.1 - 0.0055 16.3 3.0 9.5 5.9 0.1 3.9 4 0 0 4 4 4 1 Kelch motif Kelch_2 PF07646.15 PSC76751.1 - 0.011 15.7 2.1 0.74 9.9 0.0 4.0 4 0 0 4 4 4 0 Kelch motif RNase_II_C_S1 PF18614.1 PSC76751.1 - 0.065 13.2 0.2 0.14 12.1 0.2 1.6 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain Kelch_4 PF13418.6 PSC76751.1 - 5 7.2 11.3 19 5.4 0.1 4.9 6 0 0 6 6 6 0 Galactose oxidase, central domain DUF2722 PF10846.8 PSC76752.1 - 0.22 10.5 3.7 0.16 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) TFIIA PF03153.13 PSC76752.1 - 0.61 10.0 10.1 2.6 8.0 3.6 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit WD40 PF00400.32 PSC76752.1 - 0.78 10.7 13.4 22 6.1 0.0 5.9 6 1 0 6 6 6 0 WD domain, G-beta repeat Chloroa_b-bind PF00504.21 PSC76753.1 - 2.5e-48 164.6 0.1 3.2e-48 164.3 0.1 1.1 1 0 0 1 1 1 1 Chlorophyll A-B binding protein TCR PF03638.15 PSC76754.1 - 2e-24 85.6 58.1 4.1e-13 49.4 25.1 2.2 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 PSC76754.1 - 0.078 13.1 43.9 0.44 10.7 18.4 2.5 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 TFIIA PF03153.13 PSC76754.1 - 0.12 12.4 35.2 0.25 11.3 17.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CK_II_beta PF01214.18 PSC76755.1 - 9.6e-80 266.7 0.1 1.3e-79 266.2 0.1 1.2 1 0 0 1 1 1 1 Casein kinase II regulatory subunit DNA_pol3_a_NII PF11490.8 PSC76755.1 - 0.67 9.9 4.6 7.6 6.4 4.6 2.4 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II SUIM_assoc PF16619.5 PSC76755.1 - 2.3 8.3 19.1 0.91 9.6 2.1 2.5 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 CIA30 PF08547.12 PSC76756.1 - 3.4e-41 140.9 0.0 5.6e-41 140.2 0.0 1.3 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) NAD_binding_10 PF13460.6 PSC76756.1 - 1.4e-26 93.5 0.0 3.5e-15 56.4 0.0 2.2 2 0 0 2 2 2 2 NAD(P)H-binding adh_short PF00106.25 PSC76756.1 - 2.8e-06 26.9 0.1 4.5e-06 26.3 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 PSC76756.1 - 3.5e-06 26.8 0.0 9.1e-06 25.4 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family Epimerase PF01370.21 PSC76756.1 - 0.00027 20.5 0.0 0.00061 19.3 0.1 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 PSC76756.1 - 0.004 17.1 0.4 0.0063 16.4 0.4 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_4 PF07993.12 PSC76756.1 - 0.0049 16.1 0.3 0.17 11.0 0.7 2.1 2 0 0 2 2 2 1 Male sterility protein EB PF01683.18 PSC76756.1 - 0.0058 16.9 7.3 0.0058 16.9 7.3 8.0 2 1 6 8 8 8 3 EB module CBM_11 PF03425.13 PSC76756.1 - 0.0093 15.9 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) SGBP_B_XBD PF18329.1 PSC76756.1 - 0.018 15.0 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Surface glycan-binding protein B xyloglucan binding domain SBF_like PF13593.6 PSC76757.1 - 1.8e-46 158.9 18.0 2.1e-46 158.7 18.0 1.1 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) SBF PF01758.16 PSC76757.1 - 6.2e-13 48.9 7.8 6.2e-13 48.9 7.8 1.7 2 0 0 2 2 2 1 Sodium Bile acid symporter family Mem_trans PF03547.18 PSC76757.1 - 0.042 12.2 6.5 0.091 11.1 0.8 2.3 1 1 1 2 2 2 0 Membrane transport protein Dehydrin PF00257.19 PSC76757.1 - 0.05 14.2 2.1 0.065 13.8 2.1 1.2 1 0 0 1 1 1 0 Dehydrin Exostosin PF03016.15 PSC76758.1 - 7.2e-57 192.9 0.0 9.8e-57 192.4 0.0 1.2 1 0 0 1 1 1 1 Exostosin family EGF_Tenascin PF18720.1 PSC76758.1 - 0.0016 18.4 13.8 0.022 14.8 2.7 3.1 3 0 0 3 3 3 2 Tenascin EGF domain EGF_2 PF07974.13 PSC76758.1 - 0.02 15.2 16.4 0.02 15.2 16.4 4.6 4 0 0 4 4 4 0 EGF-like domain Pkinase PF00069.25 PSC76759.1 - 1.2e-36 126.5 0.0 2.5e-36 125.4 0.0 1.5 1 1 0 1 1 1 1 Protein kinase domain MIP PF00230.20 PSC76759.1 - 8.6e-21 74.7 2.2 1.4e-20 74.0 2.2 1.3 1 0 0 1 1 1 1 Major intrinsic protein Pkinase_Tyr PF07714.17 PSC76759.1 - 4.2e-14 52.4 0.0 5.9e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Tocopherol_cycl PF14249.6 PSC76759.1 - 6e-06 25.6 0.1 0.00014 21.1 0.1 2.6 3 0 0 3 3 3 1 Tocopherol cyclase IBR PF01485.21 PSC76759.1 - 0.00069 19.8 2.9 0.0013 19.0 2.9 1.3 1 0 0 1 1 1 1 IBR domain, a half RING-finger domain AF-4 PF05110.13 PSC76759.1 - 0.04 12.0 1.1 0.059 11.5 1.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein F-box_5 PF18511.1 PSC76760.1 - 0.00051 19.5 0.0 0.0011 18.5 0.0 1.4 1 0 0 1 1 1 1 F-box YueH PF14166.6 PSC76760.1 - 0.071 13.0 0.0 14 5.6 0.0 2.6 2 0 0 2 2 2 0 YueH-like protein LRR_4 PF12799.7 PSC76760.1 - 0.1 13.0 7.8 27 5.4 0.4 5.1 4 2 1 5 5 5 0 Leucine Rich repeats (2 copies) F-box-like PF12937.7 PSC76760.1 - 0.15 12.0 1.6 0.22 11.4 0.4 1.9 2 0 0 2 2 2 0 F-box-like F-box_5 PF18511.1 PSC76761.1 - 0.00043 19.8 0.0 0.00089 18.8 0.0 1.4 1 0 0 1 1 1 1 F-box LRR_8 PF13855.6 PSC76761.1 - 0.025 14.4 10.2 0.065 13.0 3.8 3.7 3 2 0 3 3 3 0 Leucine rich repeat YueH PF14166.6 PSC76761.1 - 0.053 13.4 0.0 12 5.8 0.0 2.6 2 0 0 2 2 2 0 YueH-like protein F-box-like PF12937.7 PSC76761.1 - 0.12 12.2 1.6 0.19 11.7 0.4 1.9 2 0 0 2 2 2 0 F-box-like LRR_4 PF12799.7 PSC76761.1 - 0.39 11.2 4.8 50 4.5 1.4 4.3 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) Patatin PF01734.22 PSC76762.1 - 5.5e-17 62.6 0.1 5.5e-17 62.6 0.1 3.6 3 2 0 3 3 3 1 Patatin-like phospholipase LRR_4 PF12799.7 PSC76762.1 - 1.4e-11 44.4 3.2 0.0041 17.5 0.0 3.6 3 0 0 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC76762.1 - 4.9e-09 35.8 6.7 0.00032 20.4 0.0 3.3 2 1 2 4 4 4 3 Leucine rich repeat Arm PF00514.23 PSC76762.1 - 0.0094 16.0 5.7 0.18 11.9 0.1 4.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Adaptin_N PF01602.20 PSC76762.1 - 0.058 11.9 0.6 0.099 11.2 0.6 1.2 1 0 0 1 1 1 0 Adaptin N terminal region Fes1 PF08609.10 PSC76763.1 - 9.2e-13 48.9 5.2 2.6e-12 47.5 5.2 1.8 1 0 0 1 1 1 1 Nucleotide exchange factor Fes1 YccV-like PF08755.11 PSC76764.1 - 1.6e-28 99.0 0.0 2e-28 98.8 0.0 1.1 1 0 0 1 1 1 1 Hemimethylated DNA-binding protein YccV like Fasciclin PF02469.22 PSC76765.1 - 9e-17 61.5 0.5 2.3e-16 60.2 0.5 1.7 1 0 0 1 1 1 1 Fasciclin domain SpoIIIAH PF12685.7 PSC76765.1 - 0.25 11.1 2.3 17 5.2 0.0 2.3 2 0 0 2 2 2 0 SpoIIIAH-like protein Myc_N PF01056.18 PSC76765.1 - 0.4 10.5 1.1 0.69 9.8 1.1 1.3 1 0 0 1 1 1 0 Myc amino-terminal region zf-ZPR1 PF03367.13 PSC76766.1 - 2e-66 222.8 0.0 4.9e-40 137.0 0.0 2.1 2 0 0 2 2 2 2 ZPR1 zinc-finger domain GATase_3 PF07685.14 PSC76767.1 - 3.2e-27 95.4 0.0 6.2e-27 94.5 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain CbiA PF01656.23 PSC76767.1 - 5.3e-17 62.1 0.0 8.7e-17 61.4 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.6 PSC76767.1 - 8.1e-14 51.9 0.4 2.6e-07 30.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain Peripla_BP_2 PF01497.18 PSC76767.1 - 6.6e-09 35.7 0.0 1.9e-06 27.6 0.0 2.4 2 0 0 2 2 2 2 Periplasmic binding protein DUF1611 PF07755.11 PSC76767.1 - 0.034 13.4 0.0 0.07 12.4 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1611_C) P-loop domain HTH_29 PF13551.6 PSC76767.1 - 0.35 10.9 1.9 0.84 9.7 0.8 2.3 2 0 0 2 2 2 0 Winged helix-turn helix Glyoxalase PF00903.25 PSC76769.1 - 2.9e-37 127.7 0.2 9.2e-18 64.7 0.2 2.6 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 PSC76769.1 - 7.3e-14 52.0 0.0 1.6e-05 25.1 0.0 2.8 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 PSC76769.1 - 1.9e-07 31.8 0.0 0.055 14.3 0.0 3.4 2 1 0 2 2 2 2 Glyoxalase-like domain CppA_N PF14506.6 PSC76769.1 - 0.0021 18.1 0.0 0.97 9.5 0.0 2.7 3 0 0 3 3 3 2 CppA N-terminal Glyoxalase_3 PF13468.6 PSC76769.1 - 0.058 13.5 0.0 42 4.2 0.0 3.9 2 2 0 2 2 2 0 Glyoxalase-like domain Glyoxalase PF00903.25 PSC76770.1 - 2.7e-37 127.8 0.2 8.9e-18 64.7 0.2 2.6 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 PSC76770.1 - 6.8e-14 52.1 0.0 1.6e-05 25.2 0.0 2.7 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 PSC76770.1 - 1.6e-07 32.1 0.0 0.053 14.3 0.0 3.4 2 1 0 2 2 2 2 Glyoxalase-like domain CppA_N PF14506.6 PSC76770.1 - 0.002 18.2 0.0 0.95 9.6 0.0 2.7 3 0 0 3 3 3 2 CppA N-terminal Glyoxalase_3 PF13468.6 PSC76770.1 - 0.05 13.7 0.0 40 4.3 0.0 4.0 2 2 0 2 2 2 0 Glyoxalase-like domain Dynamin_N PF00350.23 PSC76771.1 - 6.5e-21 75.1 0.8 6.8e-10 39.3 0.0 2.8 2 1 1 3 3 3 2 Dynamin family MMR_HSR1 PF01926.23 PSC76771.1 - 1.1e-11 44.8 0.0 2.8e-11 43.5 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase TMP-TENI PF02581.17 PSC76771.1 - 1.9e-09 37.1 3.0 7.4e-09 35.2 3.0 2.0 1 1 0 1 1 1 1 Thiamine monophosphate synthase GTP_EFTU PF00009.27 PSC76771.1 - 8.6e-07 28.7 0.0 1.8e-06 27.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 PSC76771.1 - 2e-05 24.5 1.3 0.0047 16.8 0.0 3.2 2 1 1 3 3 3 2 RsgA GTPase FeoB_N PF02421.18 PSC76771.1 - 0.003 17.1 0.3 0.74 9.3 0.0 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B AIG1 PF04548.16 PSC76771.1 - 0.11 11.8 8.3 0.5 9.7 0.0 2.9 3 0 0 3 3 3 0 AIG1 family SUIM_assoc PF16619.5 PSC76771.1 - 0.13 12.3 6.0 0.45 10.6 6.0 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 PSC76771.1 - 3.3 7.6 7.6 0.43 10.5 2.7 1.9 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Methyltransf_25 PF13649.6 PSC76772.1 - 2.9e-10 40.7 0.3 1.2e-08 35.5 0.4 2.9 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.13 PSC76772.1 - 5.5e-10 39.1 0.3 9.1e-10 38.4 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 PSC76772.1 - 2.8e-08 33.8 0.0 4.6e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC76772.1 - 3.3e-07 30.9 0.0 1.3e-05 25.7 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC76772.1 - 1e-06 28.6 0.1 1.7e-06 27.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PSC76772.1 - 6.8e-06 25.7 0.0 1.1e-05 25.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 PSC76772.1 - 9.8e-06 25.5 0.0 1.7e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 PSC76772.1 - 0.00016 21.1 0.0 0.00024 20.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 PSC76772.1 - 0.00042 21.0 0.3 0.002 18.8 0.1 2.3 3 1 0 3 3 2 1 Methyltransferase domain MARVEL PF01284.23 PSC76772.1 - 0.0014 18.6 13.9 0.48 10.4 4.8 2.6 1 1 1 2 2 2 2 Membrane-associating domain Methyltransf_9 PF08003.11 PSC76772.1 - 0.0031 16.5 0.0 0.0048 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.15 PSC76772.1 - 0.0051 16.5 0.0 0.0088 15.7 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Met_10 PF02475.16 PSC76772.1 - 0.068 12.9 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_16 PF10294.9 PSC76772.1 - 0.074 12.8 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_18 PF12847.7 PSC76772.1 - 0.092 12.7 0.0 0.17 11.9 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 PSC76772.1 - 0.11 12.5 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 PSC76773.1 - 8.4e-11 42.4 0.3 6.7e-09 36.3 0.4 3.0 1 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 PSC76773.1 - 3.3e-10 39.8 0.4 5.5e-10 39.1 0.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 PSC76773.1 - 1.4e-08 34.7 0.0 2.3e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 PSC76773.1 - 9.9e-08 32.5 0.1 7.5e-06 26.5 0.0 3.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC76773.1 - 5.8e-07 29.4 0.1 9.9e-07 28.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 PSC76773.1 - 3.8e-06 26.5 0.0 6.5e-06 25.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.19 PSC76773.1 - 1.2e-05 25.2 0.0 1.9e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 PSC76773.1 - 0.00011 21.6 0.0 0.00017 21.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_12 PF08242.12 PSC76773.1 - 0.00015 22.4 0.2 0.0012 19.5 0.1 2.5 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_9 PF08003.11 PSC76773.1 - 0.0029 16.6 0.0 0.0046 15.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Cons_hypoth95 PF03602.15 PSC76773.1 - 0.0033 17.1 0.0 0.0053 16.4 0.0 1.3 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_16 PF10294.9 PSC76773.1 - 0.05 13.4 0.0 0.081 12.7 0.0 1.2 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_18 PF12847.7 PSC76773.1 - 0.056 13.4 0.0 0.096 12.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 PSC76773.1 - 0.062 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein Methyltransf_32 PF13679.6 PSC76773.1 - 0.063 13.3 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain AAA PF00004.29 PSC76774.1 - 2.6e-40 137.9 0.0 4.5e-40 137.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Peptidase_M41 PF01434.18 PSC76774.1 - 4.1e-22 78.9 0.1 1.4e-20 73.9 0.1 2.2 1 1 0 1 1 1 1 Peptidase family M41 Cupin_8 PF13621.6 PSC76774.1 - 3.5e-18 66.2 0.0 7.5e-18 65.1 0.0 1.6 1 0 0 1 1 1 1 Cupin-like domain 2OG-FeII_Oxy_3 PF13640.6 PSC76774.1 - 4.8e-18 65.8 0.0 1e-17 64.8 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily JmjC PF02373.22 PSC76774.1 - 1.5e-17 64.0 0.0 2.8e-17 63.2 0.0 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase AAA_lid_3 PF17862.1 PSC76774.1 - 3.3e-12 46.0 0.4 2.2e-10 40.2 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 PSC76774.1 - 0.00087 19.3 0.0 0.002 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 PSC76774.1 - 0.0017 17.7 0.1 0.0028 16.9 0.1 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain RuvB_N PF05496.12 PSC76774.1 - 0.0031 17.3 0.0 0.0099 15.6 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 PSC76774.1 - 0.017 15.5 0.9 0.085 13.2 0.1 2.6 2 1 0 2 2 2 0 AAA ATPase domain LcrG PF07216.12 PSC76774.1 - 0.025 14.5 0.4 0.15 12.0 0.1 2.3 2 0 0 2 2 2 0 LcrG protein Cupin_2 PF07883.11 PSC76774.1 - 0.051 13.3 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 Cupin domain AAA_22 PF13401.6 PSC76774.1 - 0.15 12.3 0.1 5.3 7.3 0.0 2.5 1 1 1 2 2 2 0 AAA domain CPT PF07931.12 PSC76774.1 - 0.16 11.8 0.0 0.37 10.6 0.0 1.6 1 0 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein ShK PF01549.24 PSC76774.1 - 0.23 12.0 5.7 0.62 10.6 5.7 1.8 1 1 0 1 1 1 0 ShK domain-like UAA PF08449.11 PSC76775.1 - 9.4e-67 225.3 15.9 1.2e-66 225.0 15.9 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 PSC76775.1 - 1.4e-05 25.3 20.5 0.0082 16.3 0.9 2.3 2 0 0 2 2 2 2 EamA-like transporter family CRT-like PF08627.10 PSC76775.1 - 3.9e-05 22.8 4.4 3.9e-05 22.8 4.4 2.0 1 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like Nuc_sug_transp PF04142.15 PSC76775.1 - 0.026 13.7 9.9 0.04 13.1 9.2 1.5 1 1 0 1 1 1 0 Nucleotide-sugar transporter Zip PF02535.22 PSC76776.1 - 3.5e-08 33.1 5.1 3.5e-08 33.1 5.1 4.3 2 2 2 4 4 4 2 ZIP Zinc transporter PH PF00169.29 PSC76777.1 - 1.2e-09 38.6 0.0 1.8e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 PSC76777.1 - 0.025 14.8 0.0 0.075 13.3 0.0 1.7 2 0 0 2 2 2 0 Pleckstrin homology domain PH_17 PF18012.1 PSC76777.1 - 0.053 13.3 0.0 0.13 12.0 0.0 1.6 1 0 0 1 1 1 0 PH domain DUF2722 PF10846.8 PSC76778.1 - 0.014 14.3 1.7 0.017 14.1 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Presenilin PF01080.17 PSC76778.1 - 0.28 9.9 1.3 0.39 9.4 1.3 1.1 1 0 0 1 1 1 0 Presenilin DUF4124 PF13511.6 PSC76778.1 - 0.5 10.7 4.2 0.74 10.2 0.1 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4124) Spt20 PF12090.8 PSC76778.1 - 0.51 9.9 8.3 0.96 9.0 8.3 1.4 1 0 0 1 1 1 0 Spt20 family Peptidase_M24 PF00557.24 PSC76780.1 - 3.8e-56 190.1 0.0 5.7e-56 189.5 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 PSC76780.1 - 4.2e-23 81.4 0.0 5.3e-21 74.6 0.0 2.4 2 0 0 2 2 2 2 Aminopeptidase P, N-terminal domain rve PF00665.26 PSC76780.1 - 5.8e-19 68.4 0.0 7.3e-18 64.9 0.0 2.2 2 0 0 2 2 2 1 Integrase core domain rve_3 PF13683.6 PSC76780.1 - 0.049 13.4 0.1 0.12 12.2 0.1 1.6 1 0 0 1 1 1 0 Integrase core domain Bac_globin PF01152.21 PSC76781.1 - 3.8e-05 23.8 0.0 5.9e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Bacterial-like globin Flavodoxin_1 PF00258.25 PSC76781.1 - 0.18 12.0 0.0 0.41 10.8 0.0 1.6 1 1 0 1 1 1 0 Flavodoxin Abhydrolase_1 PF00561.20 PSC76782.1 - 2.6e-13 50.2 0.1 6.6e-13 48.9 0.1 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC76782.1 - 8.3e-10 38.3 0.7 9.1e-09 34.9 0.7 2.1 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Acetyltransf_6 PF13480.7 PSC76782.1 - 0.4 10.8 8.8 0.31 11.2 1.8 3.3 2 1 1 3 3 3 0 Acetyltransferase (GNAT) domain RRM_1 PF00076.22 PSC76783.1 - 4.8e-59 196.1 0.0 8.1e-19 67.2 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PSC76783.1 - 2.8e-08 33.7 0.0 0.08 13.0 0.0 3.3 3 0 0 3 3 3 3 RNA binding motif COX7C PF02935.16 PSC76783.1 - 6.5e-05 23.1 0.0 6.5e-05 23.1 0.0 2.0 3 0 0 3 3 3 1 Cytochrome c oxidase subunit VIIc PknH_C PF14032.6 PSC76783.1 - 0.00039 20.3 1.8 2.4 8.0 0.1 3.2 3 0 0 3 3 3 2 PknH-like extracellular domain RRM_occluded PF16842.5 PSC76783.1 - 0.00053 19.8 0.0 2.3 8.2 0.0 3.3 3 0 0 3 3 3 2 Occluded RNA-recognition motif Limkain-b1 PF11608.8 PSC76783.1 - 0.00068 19.7 0.0 1.4 9.0 0.0 3.2 3 0 0 3 3 3 1 Limkain b1 SPOR PF05036.13 PSC76783.1 - 0.003 17.9 0.0 2.5 8.6 0.0 3.6 4 0 0 4 4 4 1 Sporulation related domain YflT PF11181.8 PSC76783.1 - 0.06 13.9 0.0 2.3 8.8 0.0 3.3 4 0 0 4 4 4 0 Heat induced stress protein YflT PSII_Pbs27 PF13326.6 PSC76784.1 - 5.5e-29 101.3 0.1 6.6e-29 101.0 0.1 1.2 1 0 0 1 1 1 1 Photosystem II Pbs27 CBM_25 PF03423.13 PSC76785.1 - 5.1e-09 36.3 0.1 8.5e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain (family 25) DUF1635 PF07795.11 PSC76785.1 - 0.00088 19.2 0.1 0.0012 18.7 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) TPR_MLP1_2 PF07926.12 PSC76785.1 - 0.02 14.9 4.1 0.027 14.5 4.1 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein DUF3053 PF11254.8 PSC76785.1 - 0.036 13.7 0.8 0.05 13.2 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) FAM184 PF15665.5 PSC76785.1 - 0.038 13.8 1.4 0.051 13.3 1.4 1.1 1 0 0 1 1 1 0 Family with sequence similarity 184, A and B DUF1640 PF07798.11 PSC76785.1 - 0.061 13.4 1.6 0.087 12.9 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Sec8_exocyst PF04048.14 PSC76785.1 - 0.11 12.4 1.0 0.18 11.7 1.0 1.4 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain COG2 PF06148.11 PSC76785.1 - 0.12 12.5 1.3 0.17 12.0 1.3 1.1 1 0 0 1 1 1 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF883 PF05957.13 PSC76785.1 - 0.14 12.8 1.6 0.22 12.2 1.6 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF883) DUF724 PF05266.14 PSC76785.1 - 0.15 11.9 0.8 0.2 11.5 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Atg14 PF10186.9 PSC76785.1 - 0.17 11.0 1.0 0.21 10.6 1.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF4140 PF13600.6 PSC76785.1 - 0.2 12.1 3.5 0.36 11.3 3.5 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) RRM_1 PF00076.22 PSC76786.1 - 3.6e-39 132.4 0.0 3.1e-19 68.6 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 PSC76786.1 - 1.1e-12 47.9 0.1 3e-05 24.0 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif Nup35_RRM_2 PF14605.6 PSC76786.1 - 0.00018 21.4 0.0 0.12 12.3 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 PSC76786.1 - 0.001 19.1 0.0 0.42 10.7 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif PHM7_cyt PF14703.6 PSC76786.1 - 0.0041 17.4 3.7 2 8.6 0.1 3.6 2 1 2 4 4 4 2 Cytosolic domain of 10TM putative phosphate transporter Nup35_RRM PF05172.13 PSC76786.1 - 0.012 15.6 0.0 2.8 8.0 0.0 2.5 1 1 1 2 2 2 0 Nup53/35/40-type RNA recognition motif RL PF17797.1 PSC76786.1 - 0.06 13.3 0.0 4.9 7.2 0.0 2.4 2 0 0 2 2 2 0 RL domain DUF1866 PF08952.11 PSC76786.1 - 0.1 12.4 0.0 0.19 11.6 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1866) Asn_synthase PF00733.21 PSC76787.1 - 1.6e-22 80.7 0.1 5.2e-22 79.0 0.1 1.7 2 0 0 2 2 2 1 Asparagine synthase MFS_1 PF07690.16 PSC76787.1 - 2.5e-20 72.7 42.4 1.8e-12 46.9 9.5 2.6 2 1 0 2 2 2 2 Major Facilitator Superfamily YwiC PF14256.6 PSC76787.1 - 0.003 17.9 6.4 0.003 17.9 6.4 4.4 5 0 0 5 5 5 1 YwiC-like protein NAD_synthase PF02540.17 PSC76787.1 - 0.0066 15.6 0.0 0.011 14.9 0.0 1.2 1 0 0 1 1 1 1 NAD synthase DZR PF12773.7 PSC76787.1 - 0.0089 16.0 0.2 0.023 14.7 0.2 1.6 1 0 0 1 1 1 1 Double zinc ribbon DUF3792 PF12670.7 PSC76787.1 - 0.01 16.0 1.1 0.01 16.0 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3792) zinc_ribbon_2 PF13240.6 PSC76787.1 - 0.02 14.6 2.1 0.036 13.8 2.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.6 PSC76787.1 - 0.085 12.3 3.5 0.19 11.2 3.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain PRIMA1 PF16101.5 PSC76787.1 - 2.3 8.3 6.1 5.6 7.0 6.1 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Sugar_tr PF00083.24 PSC76787.1 - 9.8 4.9 14.8 0.81 8.5 0.4 3.1 2 1 1 3 3 3 0 Sugar (and other) transporter HMG_box PF00505.19 PSC76788.1 - 2.7e-12 46.9 0.1 6.1e-12 45.8 0.1 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 PSC76788.1 - 2.3e-11 44.1 0.2 5.5e-11 42.9 0.2 1.7 1 0 0 1 1 1 1 HMG-box domain CBFD_NFYB_HMF PF00808.23 PSC76788.1 - 1.9e-10 40.9 0.2 4.9e-10 39.5 0.2 1.7 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone CENP-T_C PF15511.6 PSC76788.1 - 0.03 14.4 0.0 0.061 13.5 0.0 1.5 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T histone fold CENP-X PF09415.10 PSC76788.1 - 0.07 13.4 0.3 0.07 13.4 0.3 2.4 2 0 0 2 2 2 0 CENP-S associating Centromere protein X Histone PF00125.24 PSC76788.1 - 0.1 13.0 3.5 0.1 12.9 0.1 2.3 3 0 0 3 3 3 0 Core histone H2A/H2B/H3/H4 Tau95_N PF17682.1 PSC76789.1 - 5.4e-16 59.0 0.0 5.4e-16 59.0 0.0 3.6 2 2 0 2 2 2 1 Tau95 Triple barrel domain Tau95 PF09734.9 PSC76789.1 - 8.3e-14 52.6 6.4 9.3e-13 49.2 0.0 2.4 2 0 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain RNA_pol_Rpb2_6 PF00562.28 PSC76790.1 - 1.4e-107 360.1 0.1 7.6e-107 357.7 0.1 2.1 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 PSC76790.1 - 7.4e-33 113.8 0.0 1.1e-32 113.2 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 PSC76790.1 - 3.9e-27 94.2 0.0 1.7e-26 92.2 0.0 2.2 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 PSC76790.1 - 5e-24 84.5 0.0 1.7e-23 82.8 0.0 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpa2_4 PF06883.12 PSC76790.1 - 8.4e-15 54.5 0.0 1.8e-14 53.4 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_2 PF04561.14 PSC76790.1 - 2e-08 34.1 0.0 3.5e-08 33.3 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 CLASP_N PF12348.8 PSC76790.1 - 2.9e-08 33.6 0.0 7e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 CLASP N terminal HEAT PF02985.22 PSC76790.1 - 0.28 11.5 2.1 61 4.3 0.0 4.0 4 0 0 4 4 4 0 HEAT repeat HEAT_2 PF13646.6 PSC76790.1 - 2.6 8.5 9.3 0.77 10.2 0.8 3.8 2 1 1 3 3 3 0 HEAT repeats cNMP_binding PF00027.29 PSC76791.1 - 1.1e-38 131.2 0.2 4.5e-18 65.1 0.0 2.4 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Limkain-b1 PF11608.8 PSC76791.1 - 0.1 12.7 0.0 0.24 11.5 0.0 1.6 1 0 0 1 1 1 0 Limkain b1 UPF0086 PF01868.16 PSC76792.1 - 4.8e-16 58.5 0.0 7.4e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function UPF0086 Abhydrolase_6 PF12697.7 PSC76793.1 - 3.7e-18 67.0 19.4 4.7e-18 66.6 19.4 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 PSC76793.1 - 4e-07 29.6 0.0 6.8e-07 28.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Thioesterase PF00975.20 PSC76793.1 - 1.7e-06 28.3 0.1 2.7e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 Thioesterase domain Abhydrolase_1 PF00561.20 PSC76793.1 - 2.3e-06 27.5 0.1 3.7e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_3 PF07859.13 PSC76793.1 - 0.0051 16.7 0.9 0.0085 16.0 0.9 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 PSC76793.1 - 0.047 13.4 0.1 0.14 11.9 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein NAD_binding_9 PF13454.6 PSC76793.1 - 0.074 13.0 0.1 0.25 11.3 0.1 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding DUF900 PF05990.12 PSC76793.1 - 0.084 12.4 0.0 0.12 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Kinesin PF00225.23 PSC76795.1 - 9.5e-108 360.1 0.0 1.8e-107 359.1 0.0 1.5 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PSC76795.1 - 1.6e-24 86.6 0.0 3.4e-24 85.5 0.0 1.6 1 0 0 1 1 1 1 Microtubule binding DUF4201 PF13870.6 PSC76795.1 - 1.1e-05 25.2 8.1 1.1e-05 25.2 8.1 9.8 6 3 3 11 11 11 3 Domain of unknown function (DUF4201) HMMR_C PF15908.5 PSC76795.1 - 5.4e-05 23.5 7.8 5.4e-05 23.5 7.8 7.5 6 2 2 10 10 10 1 Hyaluronan mediated motility receptor C-terminal Lipase_3 PF01764.25 PSC76800.1 - 9.6e-33 113.0 0.0 1.3e-32 112.6 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Hydrolase_4 PF12146.8 PSC76800.1 - 9e-06 25.1 0.1 1.6e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF2974 PF11187.8 PSC76800.1 - 4e-05 23.3 0.5 0.025 14.1 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 PSC76800.1 - 0.006 16.3 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Thioesterase PF00975.20 PSC76800.1 - 0.099 12.7 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Thioesterase domain LRR_8 PF13855.6 PSC76801.1 - 7.4e-15 54.5 3.8 0.00041 20.0 0.0 6.1 5 2 2 7 7 7 4 Leucine rich repeat LRR_4 PF12799.7 PSC76801.1 - 1.6e-10 41.0 1.1 0.17 12.3 0.0 6.5 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) F-box-like PF12937.7 PSC76801.1 - 1.3e-06 28.2 0.5 4e-06 26.6 0.2 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PSC76801.1 - 0.00023 20.9 0.0 0.00073 19.3 0.0 1.9 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.33 PSC76801.1 - 0.00084 19.6 0.1 52 5.0 0.1 5.6 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_9 PF14580.6 PSC76801.1 - 0.0035 16.9 0.0 0.017 14.7 0.0 2.2 2 0 0 2 2 2 1 Leucine-rich repeat Aldedh PF00171.22 PSC76802.1 - 1.6e-15 56.6 1.0 1.4e-12 46.9 0.7 2.2 2 0 0 2 2 2 2 Aldehyde dehydrogenase family F-box-like PF12937.7 PSC76803.1 - 1.8e-06 27.8 0.2 2.9e-06 27.0 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 PSC76803.1 - 1.8e-06 27.6 0.0 3.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 F-box domain Dynein_light PF01221.18 PSC76804.1 - 2.8e-22 78.8 0.0 3e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 DUF4764 PF15961.5 PSC76804.1 - 0.086 11.5 0.0 0.086 11.5 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4764) Cep57_CLD_2 PF14197.6 PSC76805.1 - 0.015 15.4 9.0 0.015 15.4 9.0 4.8 6 1 0 6 6 6 0 Centrosome localisation domain of PPC89 COG5 PF10392.9 PSC76805.1 - 0.031 14.5 7.2 0.11 12.7 1.0 3.1 2 0 0 2 2 2 0 Golgi transport complex subunit 5 Sec2p PF06428.11 PSC76805.1 - 0.59 10.1 18.8 0.35 10.8 1.2 4.4 4 1 1 5 5 5 0 GDP/GTP exchange factor Sec2p Prominin PF05478.11 PSC76805.1 - 0.92 7.4 5.4 0.15 10.0 0.3 2.1 2 0 0 2 2 2 0 Prominin Leu_zip PF15294.6 PSC76805.1 - 1.6 8.2 20.0 0.021 14.3 4.6 3.4 2 2 1 3 3 3 0 Leucine zipper YabA PF06156.13 PSC76805.1 - 3.9 8.2 15.7 13 6.5 1.4 4.2 4 1 0 4 4 4 0 Initiation control protein YabA DUF2730 PF10805.8 PSC76805.1 - 9.6 6.4 8.4 3.9 7.6 0.8 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF2730) DUF16 PF01519.16 PSC76805.1 - 9.8 6.7 6.3 9.7 6.7 1.2 2.9 2 0 0 2 2 2 0 Protein of unknown function DUF16 Cellulase PF00150.18 PSC76806.1 - 1.3e-19 70.7 0.0 2.3e-19 69.9 0.0 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) GFO_IDH_MocA PF01408.22 PSC76806.1 - 2e-18 67.4 0.2 3.8e-18 66.5 0.2 1.5 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold Tim17 PF02466.19 PSC76806.1 - 7.2e-05 23.1 13.5 0.00018 21.9 13.0 2.0 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SAM_1 PF00536.30 PSC76806.1 - 0.00017 21.9 0.0 0.00041 20.7 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) BCA_ABC_TP_C PF12399.8 PSC76806.1 - 0.0021 17.9 1.9 0.0054 16.6 1.9 1.8 1 0 0 1 1 1 1 Branched-chain amino acid ATP-binding cassette transporter DUF4038 PF13204.6 PSC76806.1 - 0.0057 16.3 0.0 0.0094 15.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4038) TPT PF03151.16 PSC76807.1 - 2.7e-46 158.2 14.2 3.8e-46 157.7 14.2 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family UAA PF08449.11 PSC76807.1 - 7.4e-12 45.1 14.2 1.1e-11 44.5 14.2 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 PSC76807.1 - 2.4e-11 44.0 29.2 3.7e-07 30.4 5.2 3.5 3 0 0 3 3 3 2 EamA-like transporter family GDPD PF03009.17 PSC76807.1 - 2.3e-05 24.2 0.5 0.00017 21.5 0.0 2.3 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family TMEM234 PF10639.9 PSC76807.1 - 6.2 6.9 8.6 2.4 8.2 1.5 2.4 2 0 0 2 2 2 0 Putative transmembrane family 234 EGF_2 PF07974.13 PSC76808.1 - 1.1 9.6 12.5 3.2 8.2 12.5 1.8 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 PSC76808.1 - 1.2 9.2 10.4 3.2 7.9 10.4 1.7 1 0 0 1 1 1 0 Tenascin EGF domain CMS1 PF14617.6 PSC76809.1 - 7.1e-20 71.4 0.0 1.4e-19 70.4 0.0 1.4 2 0 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit DEAD PF00270.29 PSC76809.1 - 0.056 13.2 0.0 0.069 12.9 0.0 1.2 1 0 0 1 1 1 0 DEAD/DEAH box helicase ABM PF03992.16 PSC76810.1 - 1.2e-06 28.5 0.1 3.1e-06 27.2 0.0 1.8 2 0 0 2 2 2 1 Antibiotic biosynthesis monooxygenase NIF PF03031.18 PSC76811.1 - 3e-22 79.1 0.0 5.4e-22 78.2 0.0 1.3 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 PSC76811.1 - 6.3e-07 29.7 0.0 1.2e-06 28.8 0.0 1.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 PSC76811.1 - 0.00011 22.0 0.0 0.00023 21.0 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain Proteasome PF00227.26 PSC76812.1 - 1.9e-39 135.2 0.1 2.3e-39 134.8 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit Ribosomal_L19e PF01280.20 PSC76813.1 - 1.6e-63 213.1 11.3 1.6e-63 213.1 11.3 2.7 3 0 0 3 3 3 1 Ribosomal protein L19e Fer4_13 PF13370.6 PSC76813.1 - 1.8e-17 63.6 3.5 1.8e-17 63.6 3.5 2.3 3 0 0 3 3 3 1 4Fe-4S single cluster domain of Ferredoxin I DnaJ PF00226.31 PSC76813.1 - 1.8e-13 50.4 0.0 4e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 DnaJ domain Fer4_15 PF13459.6 PSC76813.1 - 5e-07 30.4 4.3 5e-07 30.4 4.3 2.6 2 1 0 2 2 2 1 4Fe-4S single cluster domain Fer4_2 PF12797.7 PSC76813.1 - 0.026 14.6 2.5 0.082 13.0 2.5 1.9 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4 PF00037.27 PSC76813.1 - 0.055 13.3 6.7 0.054 13.3 1.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain Fer4_10 PF13237.6 PSC76813.1 - 0.23 11.6 4.0 0.69 10.1 4.0 1.9 1 1 0 1 1 1 0 4Fe-4S dicluster domain Fer4_7 PF12838.7 PSC76813.1 - 3.2 8.4 6.5 8.7 7.0 2.8 2.5 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 PSC76813.1 - 3.6 8.3 5.8 11 6.9 5.8 1.7 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_21 PF14697.6 PSC76813.1 - 4.2 7.6 7.5 1.2 9.3 2.8 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain cobW PF02492.19 PSC76814.1 - 1.8e-53 180.8 0.1 2.7e-53 180.2 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 PSC76814.1 - 4e-23 81.2 0.3 1.2e-17 63.6 0.1 2.6 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain MeaB PF03308.16 PSC76814.1 - 0.011 14.7 0.2 1.7 7.5 0.0 3.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 PSC76814.1 - 0.015 15.2 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Viral_helicase1 PF01443.18 PSC76814.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 PSC76814.1 - 0.039 14.3 2.0 0.086 13.2 0.5 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 PSC76814.1 - 0.089 13.3 0.0 0.27 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 PSC76814.1 - 0.089 12.8 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 PSC76814.1 - 0.099 12.4 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 PSC76814.1 - 0.11 13.0 0.0 0.28 11.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 PSC76814.1 - 0.11 12.6 0.1 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain PTPRCAP PF15713.5 PSC76814.1 - 0.99 9.7 17.0 2.4 8.4 10.9 2.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated SDA1 PF05285.12 PSC76814.1 - 5.2 6.4 11.9 3.1 7.1 7.7 2.0 2 0 0 2 2 2 0 SDA1 Glypican PF01153.19 PSC76814.1 - 8 5.2 8.0 2.4 6.9 4.6 1.6 2 0 0 2 2 2 0 Glypican cobW PF02492.19 PSC76815.1 - 1.8e-53 180.8 0.1 2.7e-53 180.2 0.1 1.3 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 PSC76815.1 - 4e-23 81.2 0.3 1.2e-17 63.6 0.1 2.6 2 0 0 2 2 2 2 Cobalamin synthesis protein cobW C-terminal domain MeaB PF03308.16 PSC76815.1 - 0.011 14.7 0.2 1.7 7.5 0.0 3.0 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_GTPase PF03193.16 PSC76815.1 - 0.015 15.2 0.0 1.7 8.5 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase Viral_helicase1 PF01443.18 PSC76815.1 - 0.019 14.7 0.0 0.036 13.8 0.0 1.5 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_16 PF13191.6 PSC76815.1 - 0.039 14.3 2.0 0.086 13.2 0.5 2.5 2 1 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 PSC76815.1 - 0.089 13.3 0.0 0.27 11.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 PSC76815.1 - 0.089 12.8 0.1 0.17 11.9 0.1 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_29 PF13555.6 PSC76815.1 - 0.099 12.4 0.1 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 PSC76815.1 - 0.11 13.0 0.0 0.28 11.7 0.0 1.8 1 0 0 1 1 1 0 ABC transporter AAA_33 PF13671.6 PSC76815.1 - 0.11 12.6 0.1 0.3 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain PTPRCAP PF15713.5 PSC76815.1 - 0.99 9.7 17.0 2.4 8.4 10.9 2.5 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated SDA1 PF05285.12 PSC76815.1 - 5.2 6.4 11.9 3.1 7.1 7.7 2.0 2 0 0 2 2 2 0 SDA1 Glypican PF01153.19 PSC76815.1 - 8 5.2 8.0 2.4 6.9 4.6 1.6 2 0 0 2 2 2 0 Glypican DNA_pol_lambd_f PF10391.9 PSC76816.1 - 4.2e-17 61.7 0.0 8.5e-17 60.7 0.0 1.5 1 0 0 1 1 1 1 Fingers domain of DNA polymerase lambda DNA_pol_B_palm PF14792.6 PSC76816.1 - 3.3e-13 49.9 0.0 5.8e-13 49.1 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.6 PSC76816.1 - 2.5e-05 24.3 0.2 0.0006 19.9 0.0 2.8 3 0 0 3 3 3 1 DNA polymerase beta thumb Fasciclin PF02469.22 PSC76818.1 - 7e-05 23.1 0.0 0.00012 22.3 0.0 1.4 1 1 0 1 1 1 1 Fasciclin domain PRODH PF18327.1 PSC76818.1 - 0.028 14.6 0.2 0.21 11.8 0.0 2.5 2 0 0 2 2 2 0 Proline utilization A proline dehydrogenase N-terminal domain PucR PF07905.11 PSC76819.1 - 0.038 14.3 0.4 0.12 12.7 0.1 1.8 2 0 0 2 2 2 0 Purine catabolism regulatory protein-like family FAD_binding_4 PF01565.23 PSC76820.1 - 1.8e-24 86.1 0.2 3.2e-24 85.2 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 PSC76820.1 - 1.1e-17 64.7 0.0 4e-17 62.9 0.0 1.8 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase FAD_binding_4 PF01565.23 PSC76821.1 - 1.8e-24 86.1 0.2 3.2e-24 85.2 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain ALO PF04030.14 PSC76821.1 - 1.1e-17 64.7 0.0 4e-17 62.9 0.0 1.8 1 1 0 1 1 1 1 D-arabinono-1,4-lactone oxidase Pkinase PF00069.25 PSC76822.1 - 4.5e-70 236.0 0.1 4.1e-69 232.9 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC76822.1 - 2e-30 105.9 0.1 1.4e-29 103.2 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Ribosomal_L24e PF01246.20 PSC76822.1 - 2.6e-25 88.4 0.1 5.4e-25 87.4 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e ubiquitin PF00240.23 PSC76822.1 - 1.1e-09 37.9 0.0 2.6e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin family STI1 PF17830.1 PSC76822.1 - 0.00047 20.0 53.1 0.0091 15.9 5.8 5.4 2 2 2 4 4 4 3 STI1 domain Rad60-SLD_2 PF13881.6 PSC76822.1 - 0.0021 18.1 0.0 0.011 15.9 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD PF11976.8 PSC76822.1 - 0.0028 17.5 0.0 0.0074 16.1 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 PSC76822.1 - 0.017 15.7 1.7 0.058 14.0 0.0 2.7 4 0 0 4 4 3 0 DUF2407 ubiquitin-like domain LPD22 PF18834.1 PSC76822.1 - 0.022 15.0 7.8 1.9 8.7 2.9 4.0 2 1 1 3 3 3 0 Large polyvalent protein associated domain 22 UBA PF00627.31 PSC76822.1 - 0.022 14.7 0.3 0.22 11.5 0.0 2.9 3 0 0 3 3 3 0 UBA/TS-N domain Pkinase_fungal PF17667.1 PSC76822.1 - 0.16 10.7 0.0 5 5.8 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase Ubiquitin_4 PF18036.1 PSC76822.1 - 0.46 10.6 1.8 3.2 7.9 0.0 2.8 2 1 0 2 2 2 0 Ubiquitin-like domain RPN13_C PF16550.5 PSC76822.1 - 0.55 10.4 18.5 0.81 9.9 5.1 3.4 2 1 1 3 3 3 0 UCH-binding domain GerD PF17898.1 PSC76822.1 - 1 9.4 33.2 0.023 14.6 13.6 4.0 2 2 1 3 3 3 0 Spore germination GerD central core domain ABC2_membrane PF01061.24 PSC76823.1 - 8e-31 107.1 17.4 1.1e-30 106.6 17.4 1.2 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 PSC76823.1 - 1.5e-20 74.1 0.0 2.1e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 PSC76823.1 - 1.7 7.7 8.9 2.3 7.2 8.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Bestrophin PF01062.21 PSC76825.1 - 5.4e-46 157.3 0.1 7.4e-46 156.9 0.1 1.2 1 0 0 1 1 1 1 Bestrophin, RFP-TM, chloride channel Asp23 PF03780.13 PSC76825.1 - 0.03 14.7 0.1 0.072 13.5 0.1 1.5 1 0 0 1 1 1 0 Asp23 family, cell envelope-related function BMFP PF04380.13 PSC76825.1 - 0.15 12.6 0.6 0.44 11.1 0.6 1.8 1 0 0 1 1 1 0 Membrane fusogenic activity TMEM237 PF15383.6 PSC76825.1 - 0.16 11.1 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 237 Mannosyl_trans2 PF04188.13 PSC76826.1 - 1.5e-42 146.4 0.0 1.8e-34 119.8 0.4 2.1 2 0 0 2 2 2 2 Mannosyltransferase (PIG-V) EamA PF00892.20 PSC76826.1 - 3.5e-06 27.2 10.9 3.5e-06 27.2 10.9 4.1 4 1 1 5 5 5 3 EamA-like transporter family PIG-U PF06728.13 PSC76826.1 - 0.034 13.2 0.1 0.064 12.3 0.1 1.4 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U Mannosyl_trans2 PF04188.13 PSC76827.1 - 1.5e-42 146.5 0.0 1.8e-34 119.8 0.4 2.1 2 0 0 2 2 2 2 Mannosyltransferase (PIG-V) EamA PF00892.20 PSC76827.1 - 3.5e-06 27.2 10.9 3.5e-06 27.2 10.9 4.1 4 1 1 5 5 5 3 EamA-like transporter family PIG-U PF06728.13 PSC76827.1 - 0.034 13.2 0.1 0.064 12.3 0.1 1.4 1 0 0 1 1 1 0 GPI transamidase subunit PIG-U Telomere_reg-2 PF10193.9 PSC76828.1 - 7.5e-12 45.7 0.0 6.5e-11 42.6 0.0 2.3 1 1 0 1 1 1 1 Telomere length regulation protein HEAT PF02985.22 PSC76828.1 - 7.6 7.1 0.0 7.6 7.1 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat GATA PF00320.27 PSC76829.1 - 1.7e-09 37.1 18.5 5.1e-07 29.2 5.9 10.6 11 0 0 11 11 11 6 GATA zinc finger Sporozoite_P67 PF05642.11 PSC76829.1 - 0.14 10.2 2.7 0.27 9.3 0.6 2.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Myc_N PF01056.18 PSC76829.1 - 0.89 9.4 3.5 2.5 7.9 3.5 1.7 1 0 0 1 1 1 0 Myc amino-terminal region FAM176 PF14851.6 PSC76829.1 - 1.5 8.5 6.9 4.9 6.8 6.9 1.8 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 PSC76829.1 - 1.5 9.2 12.7 0.67 10.4 9.3 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 PSC76829.1 - 2.2 6.5 3.5 3.7 5.7 3.5 1.2 1 0 0 1 1 1 0 CDC45-like protein ADD_ATRX PF17981.1 PSC76829.1 - 6.9 6.6 34.8 6.5 6.7 0.2 7.6 7 0 0 7 7 7 0 Cysteine Rich ADD domain DNA_pol_phi PF04931.13 PSC76829.1 - 9.1 4.2 5.4 14 3.7 5.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi GATA PF00320.27 PSC76830.1 - 1.7e-09 37.1 18.5 5e-07 29.2 5.9 10.7 11 0 0 11 11 11 6 GATA zinc finger Sporozoite_P67 PF05642.11 PSC76830.1 - 0.14 10.2 2.7 0.26 9.3 0.6 2.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Myc_N PF01056.18 PSC76830.1 - 0.88 9.4 3.5 2.5 7.9 3.5 1.7 1 0 0 1 1 1 0 Myc amino-terminal region FAM176 PF14851.6 PSC76830.1 - 1.5 8.5 6.9 4.8 6.8 6.9 1.8 1 0 0 1 1 1 0 FAM176 family PBP1_TM PF14812.6 PSC76830.1 - 1.5 9.2 12.7 0.66 10.4 9.3 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.14 PSC76830.1 - 2.2 6.5 3.5 3.6 5.8 3.5 1.2 1 0 0 1 1 1 0 CDC45-like protein ADD_ATRX PF17981.1 PSC76830.1 - 5.1 7.0 34.8 6.5 6.7 0.2 7.8 7 0 0 7 7 7 0 Cysteine Rich ADD domain DNA_pol_phi PF04931.13 PSC76830.1 - 9 4.3 5.4 13 3.7 5.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi WD40 PF00400.32 PSC76831.1 - 3e-15 56.3 17.2 1.1 10.2 0.0 9.8 10 0 0 10 10 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC76831.1 - 8.2e-06 26.0 0.0 3.9 7.8 0.0 5.1 5 1 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain DGOK PF05035.12 PSC76831.1 - 0.00097 18.1 1.2 0.22 10.4 0.1 2.3 2 0 0 2 2 2 2 2-keto-3-deoxy-galactonokinase DUF4394 PF14339.6 PSC76831.1 - 0.0064 15.9 0.0 1.2 8.5 0.0 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4394) PQQ_3 PF13570.6 PSC76831.1 - 0.0099 16.3 0.1 30 5.3 0.0 5.2 6 0 0 6 6 5 0 PQQ-like domain zf-CCHC PF00098.23 PSC76831.1 - 0.011 15.7 32.0 1.9 8.7 2.7 4.9 4 0 0 4 4 4 0 Zinc knuckle Ge1_WD40 PF16529.5 PSC76831.1 - 0.013 14.5 1.4 33 3.3 0.0 4.0 4 0 0 4 4 4 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 PSC76831.1 - 0.017 13.8 0.0 9.9 4.7 0.0 3.1 3 1 1 4 4 4 0 Nucleoporin Nup120/160 CPSF_A PF03178.15 PSC76831.1 - 0.023 14.0 0.0 81 2.4 0.0 3.9 4 0 0 4 4 4 0 CPSF A subunit region Castor_Poll_mid PF06241.12 PSC76831.1 - 0.043 13.8 0.0 27 4.8 0.0 3.4 4 0 0 4 4 4 0 Castor and Pollux, part of voltage-gated ion channel Connexin PF00029.19 PSC76831.1 - 0.2 11.4 0.2 9 6.0 0.0 2.4 2 0 0 2 2 2 0 Connexin BNR_6 PF15899.5 PSC76831.1 - 0.77 10.0 2.2 47 4.5 0.2 2.7 2 0 0 2 2 2 0 BNR-Asp box repeat zf-CCHC_4 PF14392.6 PSC76831.1 - 3.2 7.6 26.1 1.3 8.8 1.2 4.4 2 2 2 4 4 4 0 Zinc knuckle PQQ PF01011.21 PSC76831.1 - 4.1 7.5 6.4 26 5.0 0.0 3.6 4 0 0 4 4 4 0 PQQ enzyme repeat WD40 PF00400.32 PSC76833.1 - 0.5 11.3 4.9 15 6.6 0.0 5.0 6 0 0 6 6 6 0 WD domain, G-beta repeat Pkinase PF00069.25 PSC76834.1 - 1.2e-54 185.5 0.0 3.4e-53 180.7 0.0 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC76834.1 - 3.2e-36 124.9 0.0 1.8e-35 122.5 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase ADH_zinc_N PF00107.26 PSC76834.1 - 6.9e-16 58.4 0.1 2e-15 56.9 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 PSC76834.1 - 4.3e-12 45.9 0.0 1e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 PSC76834.1 - 8.5e-08 33.3 0.0 5.6e-07 30.7 0.0 2.4 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Pkinase_fungal PF17667.1 PSC76834.1 - 2.9e-05 23.0 0.0 5.1e-05 22.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase NmrA PF05368.13 PSC76834.1 - 0.016 14.8 1.0 0.025 14.1 0.3 1.6 2 0 0 2 2 2 0 NmrA-like family AC_N PF16214.5 PSC76834.1 - 0.15 11.2 2.9 0.33 10.1 2.9 1.4 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region NAD_binding_10 PF13460.6 PSC76834.1 - 0.16 11.9 0.8 0.26 11.1 0.8 1.3 1 0 0 1 1 1 0 NAD(P)H-binding LON_substr_bdg PF02190.16 PSC76835.1 - 0.00055 19.9 0.0 0.00098 19.0 0.0 1.3 1 0 0 1 1 1 1 ATP-dependent protease La (LON) substrate-binding domain Utp21 PF04192.12 PSC76836.1 - 2.8e-50 171.0 0.0 1.8e-49 168.3 0.0 2.0 2 0 0 2 2 2 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 PSC76836.1 - 1.1e-21 76.7 14.9 5.5e-07 30.2 0.3 9.8 11 1 0 11 11 11 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 PSC76836.1 - 1.7e-07 31.5 0.0 0.0062 16.8 0.0 5.4 4 1 2 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 PSC76836.1 - 0.043 12.3 0.0 7.9 4.9 0.0 2.3 2 0 0 2 2 2 0 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 PSC76836.1 - 0.1 11.3 0.0 12 4.5 0.0 2.6 1 1 2 3 3 3 0 Nup133 N terminal like Nup160 PF11715.8 PSC76836.1 - 0.14 10.8 0.1 13 4.3 0.0 3.1 2 1 2 4 4 4 0 Nucleoporin Nup120/160 Caudo_TAP PF02413.17 PSC76836.1 - 0.96 9.6 3.6 2.5 8.3 3.6 1.6 1 0 0 1 1 1 0 Caudovirales tail fibre assembly protein, lambda gpK KDZ PF18758.1 PSC76837.1 - 2.6e-24 86.1 0.7 3.6e-24 85.6 0.7 1.1 1 0 0 1 1 1 1 Kyakuja-Dileera-Zisupton transposase DUF2269 PF10027.9 PSC76837.1 - 0.0021 18.1 0.9 0.0045 17.1 0.9 1.6 1 0 0 1 1 1 1 Predicted integral membrane protein (DUF2269) MFS_1_like PF12832.7 PSC76838.1 - 3e-43 148.2 1.6 1.3e-35 123.0 0.1 3.0 2 1 1 3 3 3 3 MFS_1 like family Fasciclin PF02469.22 PSC76838.1 - 1.2e-11 45.0 0.0 2.1e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain MFS_1 PF07690.16 PSC76838.1 - 4.9e-09 35.6 41.3 2.1e-05 23.7 13.9 4.1 2 2 2 4 4 4 4 Major Facilitator Superfamily Nuc_H_symport PF03825.16 PSC76838.1 - 3.5e-06 26.3 0.5 3.5e-06 26.3 0.5 1.6 2 0 0 2 2 2 1 Nucleoside H+ symporter MIOX PF05153.15 PSC76839.1 - 2.4e-57 194.4 0.0 3.1e-55 187.5 0.0 2.4 2 1 0 2 2 2 2 Myo-inositol oxygenase Glyco_transf_10 PF00852.19 PSC76840.1 - 1.3e-22 80.3 0.0 2.1e-22 79.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 PSC76840.1 - 9e-09 35.8 0.1 2.9e-08 34.1 0.0 1.9 2 0 0 2 2 2 1 Fucosyltransferase, N-terminal EXS PF03124.14 PSC76841.1 - 2.5e-78 263.7 20.1 3.1e-78 263.4 20.1 1.1 1 0 0 1 1 1 1 EXS family RWP-RK PF02042.15 PSC76841.1 - 3.6e-17 62.1 0.0 7.9e-17 61.0 0.0 1.6 1 0 0 1 1 1 1 RWP-RK domain PIP5K PF01504.18 PSC76841.1 - 0.56 9.4 6.4 1.3 8.1 6.4 1.5 1 0 0 1 1 1 0 Phosphatidylinositol-4-phosphate 5-Kinase SMYLE_N PF18615.1 PSC76841.1 - 1 8.8 9.3 2.6 7.5 9.3 1.6 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain CDC45 PF02724.14 PSC76841.1 - 1 7.6 10.5 0.18 10.1 6.5 1.8 2 0 0 2 2 2 0 CDC45-like protein SLC12 PF03522.15 PSC76841.1 - 1.2 8.1 9.8 2.8 6.9 9.8 1.5 1 0 0 1 1 1 0 Solute carrier family 12 Connexin PF00029.19 PSC76841.1 - 2.6 7.7 7.8 6.9 6.4 7.8 1.7 1 0 0 1 1 1 0 Connexin Plasmodium_Vir PF05795.11 PSC76841.1 - 7 6.0 8.0 13 5.1 8.0 1.4 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4638 PF15472.6 PSC76841.1 - 9.8 5.8 9.1 23 4.6 9.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) CBM_20 PF00686.19 PSC76842.1 - 4.5e-12 45.7 0.0 8.8e-12 44.8 0.0 1.5 1 0 0 1 1 1 1 Starch binding domain Hrs_helical PF12210.8 PSC76842.1 - 5.3 7.7 9.6 1.8 9.1 3.2 3.0 3 0 0 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate A_deaminase PF00962.22 PSC76844.1 - 1.3e-45 156.1 0.0 7.5e-28 97.8 0.0 2.1 1 1 1 2 2 2 2 Adenosine/AMP deaminase ANAPC4_WD40 PF12894.7 PSC76845.1 - 5.6e-14 52.2 0.0 0.01 16.1 0.0 4.6 3 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 PSC76845.1 - 3e-08 34.2 8.5 0.32 11.9 0.0 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat Prefoldin_2 PF01920.20 PSC76846.1 - 2e-24 85.5 3.3 2.3e-24 85.4 3.3 1.0 1 0 0 1 1 1 1 Prefoldin subunit Spc24 PF08286.11 PSC76846.1 - 0.0097 16.1 5.9 1 9.7 1.0 2.1 1 1 1 2 2 2 2 Spc24 subunit of Ndc80 FlaC_arch PF05377.11 PSC76846.1 - 0.014 15.7 1.2 1.3 9.5 0.1 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) HOOK PF05622.12 PSC76846.1 - 0.016 13.4 4.5 0.54 8.3 0.2 2.0 1 1 1 2 2 2 0 HOOK protein Seryl_tRNA_N PF02403.22 PSC76846.1 - 0.02 15.1 4.4 2.3 8.5 0.6 2.1 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain NPV_P10 PF05531.12 PSC76846.1 - 0.044 14.3 0.9 3.5 8.1 0.1 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.11 PSC76846.1 - 0.045 14.0 0.5 3.9 7.8 0.0 2.1 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) ADIP PF11559.8 PSC76846.1 - 0.047 13.8 6.0 0.12 12.5 0.8 2.0 2 0 0 2 2 2 0 Afadin- and alpha -actinin-Binding Filament PF00038.21 PSC76846.1 - 0.063 12.8 6.2 0.061 12.9 1.2 2.0 2 0 0 2 2 2 0 Intermediate filament protein DUF4164 PF13747.6 PSC76846.1 - 0.064 13.5 8.0 0.31 11.3 1.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) DUF4618 PF15397.6 PSC76846.1 - 0.066 12.6 3.3 0.11 12.0 3.3 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4618) DUF2730 PF10805.8 PSC76846.1 - 0.095 12.8 3.0 2.9 8.0 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2730) SKA2 PF16740.5 PSC76846.1 - 0.16 11.8 3.6 0.74 9.6 0.3 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 2 Lebercilin PF15619.6 PSC76846.1 - 0.18 11.5 7.3 2.9 7.5 1.7 2.1 2 0 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease DUF16 PF01519.16 PSC76846.1 - 0.2 12.2 2.1 4 8.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function DUF16 Jnk-SapK_ap_N PF09744.9 PSC76846.1 - 0.2 11.8 6.2 0.89 9.8 0.6 2.0 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 Cluap1 PF10234.9 PSC76846.1 - 0.24 10.8 4.2 0.48 9.8 4.2 1.5 1 1 0 1 1 1 0 Clusterin-associated protein-1 SlyX PF04102.12 PSC76846.1 - 0.24 12.0 6.1 5.7 7.6 0.4 2.3 2 0 0 2 2 2 0 SlyX KfrA_N PF11740.8 PSC76846.1 - 0.28 11.9 8.8 0.47 11.2 8.6 1.4 1 1 0 1 1 1 0 Plasmid replication region DNA-binding N-term DUF1664 PF07889.12 PSC76846.1 - 0.29 11.2 2.0 1.5 8.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) CdvA PF18822.1 PSC76846.1 - 0.37 10.6 7.0 1 9.2 1.3 2.2 2 0 0 2 2 2 0 CdvA-like coiled-coil domain APG6_N PF17675.1 PSC76846.1 - 0.39 11.2 10.6 0.44 11.1 0.9 2.0 2 0 0 2 2 2 0 Apg6 coiled-coil region ZapB PF06005.12 PSC76846.1 - 0.41 11.1 9.7 0.83 10.1 5.6 2.2 1 1 1 2 2 2 0 Cell division protein ZapB COG2 PF06148.11 PSC76846.1 - 0.43 10.7 4.8 1.1 9.3 0.5 2.0 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 THOC7 PF05615.13 PSC76846.1 - 0.46 10.8 5.5 3.7 7.8 5.5 2.1 1 1 0 1 1 1 0 Tho complex subunit 7 DUF3450 PF11932.8 PSC76846.1 - 0.46 9.7 5.6 2.2 7.5 1.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) QLQ PF08880.11 PSC76846.1 - 0.7 9.7 4.8 2.1 8.1 1.4 2.2 2 0 0 2 2 2 0 QLQ YabA PF06156.13 PSC76846.1 - 0.7 10.6 3.4 11 6.8 0.3 2.2 1 1 1 2 2 2 0 Initiation control protein YabA FlxA PF14282.6 PSC76846.1 - 1 9.4 6.7 5.1 7.1 2.4 2.2 2 0 0 2 2 2 0 FlxA-like protein DUF4140 PF13600.6 PSC76846.1 - 1.1 9.7 5.6 6.4 7.3 0.3 2.2 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) DivIC PF04977.15 PSC76846.1 - 1.2 9.0 7.6 1.7 8.5 0.8 2.4 2 1 0 2 2 2 0 Septum formation initiator Spc7 PF08317.11 PSC76846.1 - 3.2 6.5 8.5 26 3.6 8.5 1.9 1 1 0 1 1 1 0 Spc7 kinetochore protein Csm1_N PF18504.1 PSC76846.1 - 3.7 7.9 8.0 12 6.3 1.4 2.5 2 1 0 2 2 2 0 Csm1 N-terminal domain Tim17 PF02466.19 PSC76847.1 - 7.4e-30 103.6 3.3 7.4e-30 103.6 3.3 1.6 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF2076 PF09849.9 PSC76847.1 - 0.014 15.5 0.2 0.014 15.5 0.2 1.8 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) p450 PF00067.22 PSC76848.1 - 2e-85 287.3 0.0 2.7e-85 286.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 GCV_T PF01571.21 PSC76849.1 - 9.8e-89 297.1 0.0 1.3e-88 296.7 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 PSC76849.1 - 8.3e-18 64.1 0.1 2.4e-17 62.6 0.1 1.8 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain Citrate_synt PF00285.21 PSC76850.1 - 4.4e-130 433.9 0.0 5.4e-130 433.7 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DUF2048 PF09752.9 PSC76851.1 - 1e-81 274.8 0.0 2.7e-81 273.4 0.0 1.6 1 1 0 1 1 1 1 Abhydrolase domain containing 18 Abhydrolase_1 PF00561.20 PSC76851.1 - 0.0029 17.3 0.1 0.51 9.9 0.0 2.4 2 0 0 2 2 2 2 alpha/beta hydrolase fold DUF420 PF04238.12 PSC76852.1 - 0.087 13.1 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF420) DUF420 PF04238.12 PSC76853.1 - 0.087 13.1 0.0 0.11 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF420) Peptidase_C1 PF00112.23 PSC76854.1 - 1e-37 130.3 0.2 5.4e-37 128.0 0.2 1.9 1 1 0 1 1 1 1 Papain family cysteine protease Exo_endo_phos PF03372.23 PSC76855.1 - 4.2e-09 36.3 0.0 8.5e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family EF-hand_5 PF13202.6 PSC76855.1 - 0.2 11.2 0.0 0.44 10.1 0.0 1.6 1 0 0 1 1 1 0 EF hand Peptidase_S8 PF00082.22 PSC76857.1 - 3.6e-23 82.3 4.9 2.9e-11 43.2 0.9 2.3 1 1 1 2 2 2 2 Subtilase family SR-25 PF10500.9 PSC76857.1 - 0.0041 16.7 19.8 0.0041 16.7 19.8 3.2 3 1 0 3 3 3 1 Nuclear RNA-splicing-associated protein T2SSC PF11356.8 PSC76857.1 - 1.8 8.5 5.6 0.61 10.0 1.8 2.2 2 0 0 2 2 2 0 Type II secretion system protein C DNA_photolyase PF00875.18 PSC76858.1 - 5.8e-25 88.2 0.5 1e-24 87.4 0.0 1.6 2 0 0 2 2 2 1 DNA photolyase Abhydrolase_6 PF12697.7 PSC76858.1 - 1e-23 85.1 8.5 1e-23 85.1 8.5 4.4 2 1 1 4 4 4 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 PSC76858.1 - 1.3e-18 67.6 0.1 6.1e-18 65.4 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC76858.1 - 4.3e-17 62.2 0.2 1.1e-15 57.6 0.0 2.5 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Esterase PF00756.20 PSC76858.1 - 0.026 14.2 0.6 1.1 8.8 0.0 2.6 2 0 0 2 2 2 0 Putative esterase Ndr PF03096.14 PSC76858.1 - 0.17 10.5 0.0 0.31 9.7 0.0 1.3 1 0 0 1 1 1 0 Ndr family Abhydrolase_5 PF12695.7 PSC76858.1 - 0.21 11.4 0.6 0.75 9.5 0.6 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family UPF0020 PF01170.18 PSC76859.1 - 1.8e-29 102.8 0.0 5.5e-29 101.3 0.0 1.7 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 N6_Mtase PF02384.16 PSC76859.1 - 0.079 12.2 0.0 0.27 10.4 0.0 1.7 1 1 0 1 1 1 0 N-6 DNA Methylase MTS PF05175.14 PSC76859.1 - 0.12 11.9 0.0 0.21 11.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Adaptin_N PF01602.20 PSC76860.1 - 4.5e-83 279.6 0.0 5.9e-83 279.2 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 PSC76860.1 - 8.9e-36 123.4 0.0 1.6e-33 116.1 0.0 3.2 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 Pectate_lyase_3 PF12708.7 PSC76860.1 - 6.9e-15 55.5 0.0 2e-14 54.0 0.0 1.8 1 0 0 1 1 1 1 Pectate lyase superfamily protein HEAT_2 PF13646.6 PSC76860.1 - 2.9e-07 30.8 2.7 0.0089 16.4 0.0 4.4 4 1 1 5 5 5 2 HEAT repeats B2-adapt-app_C PF09066.10 PSC76860.1 - 2.4e-06 27.6 0.0 5.4e-06 26.5 0.0 1.6 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT PF02985.22 PSC76860.1 - 0.0011 19.0 2.2 19 5.9 0.0 6.0 7 0 0 7 7 7 1 HEAT repeat Coatomer_E PF04733.14 PSC76860.1 - 0.019 14.4 0.0 0.043 13.2 0.0 1.5 1 0 0 1 1 1 0 Coatomer epsilon subunit Beta_helix PF13229.6 PSC76860.1 - 0.051 13.4 0.1 0.097 12.5 0.1 1.3 1 0 0 1 1 1 0 Right handed beta helix region Ribosomal_L15e PF00827.17 PSC76861.1 - 3.7e-92 307.3 4.7 5.4e-92 306.8 4.7 1.3 1 0 0 1 1 1 1 Ribosomal L15 EI24 PF07264.11 PSC76861.1 - 2.4e-34 119.1 19.1 4.3e-34 118.3 19.1 1.5 1 0 0 1 1 1 1 Etoposide-induced protein 2.4 (EI24) zf-C3HC4_3 PF13920.6 PSC76861.1 - 4.1e-07 29.7 2.9 4.1e-07 29.7 2.9 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PSC76861.1 - 3.2e-06 26.9 3.6 3.2e-06 26.9 3.6 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 PSC76861.1 - 0.0013 18.6 6.0 0.0013 18.6 6.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 PSC76861.1 - 0.0036 17.6 5.6 0.0036 17.6 5.6 2.7 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 PSC76861.1 - 0.1 12.7 2.4 0.29 11.2 2.4 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 PSC76861.1 - 0.12 12.6 2.1 0.55 10.4 2.1 2.2 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Raffinose_syn PF05691.12 PSC76862.1 - 5.2e-156 520.5 0.0 6e-110 368.2 0.0 3.0 3 0 0 3 3 3 3 Raffinose synthase or seed imbibition protein Sip1 UDPG_MGDP_dh_N PF03721.14 PSC76863.1 - 4.4e-63 212.2 0.3 4.4e-63 212.2 0.3 1.5 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain UDPG_MGDP_dh_C PF03720.15 PSC76863.1 - 8.6e-32 109.7 0.0 4e-31 107.5 0.0 2.1 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain UDPG_MGDP_dh PF00984.19 PSC76863.1 - 9.7e-32 109.0 0.1 2.7e-31 107.6 0.1 1.8 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, central domain NAD_binding_2 PF03446.15 PSC76863.1 - 0.00082 19.6 0.3 0.0031 17.7 0.1 2.1 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 PSC76863.1 - 0.038 13.9 1.4 0.081 12.8 0.0 2.3 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Sacchrp_dh_NADP PF03435.18 PSC76863.1 - 0.054 13.8 0.0 0.15 12.4 0.0 1.8 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain Ldh_1_N PF00056.23 PSC76863.1 - 0.072 13.2 0.1 0.22 11.6 0.0 1.9 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.22 PSC76863.1 - 0.13 13.1 0.0 0.39 11.5 0.0 1.9 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold Exo_endo_phos PF03372.23 PSC76864.1 - 3.8e-08 33.1 1.4 6.4e-08 32.4 1.4 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Abhydrolase_1 PF00561.20 PSC76865.1 - 9e-07 28.8 0.1 4e-06 26.7 0.1 1.8 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 PSC76865.1 - 1.4e-05 24.5 0.3 7.2e-05 22.2 0.3 1.9 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 PSC76865.1 - 1.5e-05 24.7 0.0 3.6e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 X-Pro dipeptidyl-peptidase (S15 family) Pectate_lyase_3 PF12708.7 PSC76865.1 - 0.0047 16.8 0.1 0.46 10.3 0.0 2.4 2 0 0 2 2 2 1 Pectate lyase superfamily protein DLH PF01738.18 PSC76865.1 - 0.021 14.4 0.0 0.036 13.6 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family DUF818 PF05677.12 PSC76865.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Chlamydia CHLPS protein (DUF818) DIRP PF06584.13 PSC76866.1 - 5e-22 78.1 0.0 9e-22 77.3 0.0 1.4 1 0 0 1 1 1 1 DIRP Myb_DNA-binding PF00249.31 PSC76866.1 - 5.3e-05 23.3 0.0 0.00012 22.2 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 PSC76866.1 - 0.0027 17.6 0.0 0.1 12.5 0.0 2.4 2 0 0 2 2 2 1 Myb DNA-binding like PolyA_pol_RNAbd PF12627.7 PSC76867.1 - 1.8e-05 24.4 0.0 3.8e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A Rad1 PF02144.16 PSC76868.1 - 3.5e-11 42.7 0.0 6.4e-11 41.8 0.0 1.4 1 1 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Abhydrolase_2 PF02230.16 PSC76869.1 - 5.4e-52 176.7 0.0 8.5e-52 176.1 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 PSC76869.1 - 2.9e-06 26.7 0.0 0.02 14.1 0.0 3.1 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 PSC76869.1 - 0.00025 21.7 11.4 0.00025 21.7 11.4 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family Esterase PF00756.20 PSC76869.1 - 0.00027 20.6 0.0 0.0005 19.8 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_1 PF00561.20 PSC76869.1 - 0.00048 19.8 0.4 0.19 11.3 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold DLH PF01738.18 PSC76869.1 - 0.0052 16.4 0.0 0.0093 15.5 0.0 1.3 1 0 0 1 1 1 1 Dienelactone hydrolase family Cutinase PF01083.22 PSC76869.1 - 0.017 15.1 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 Cutinase Peptidase_S9 PF00326.21 PSC76869.1 - 0.022 14.2 0.0 2.2 7.7 0.0 2.4 1 1 1 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 PSC76869.1 - 0.026 14.4 0.3 0.07 13.0 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold SAP PF02037.27 PSC76869.1 - 0.084 12.7 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 SAP domain Pkinase PF00069.25 PSC76870.1 - 2.7e-18 66.3 0.0 4.5e-18 65.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC76870.1 - 6.6e-06 25.6 0.0 1.1e-05 24.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 PSC76870.1 - 0.0047 16.3 0.0 0.0096 15.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 PSC76870.1 - 0.06 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TMEM210 PF15195.6 PSC76870.1 - 0.23 11.9 1.2 2 8.9 0.0 3.1 3 0 0 3 3 3 0 TMEM210 family CLP_protease PF00574.23 PSC76870.1 - 0.27 11.1 2.6 1.9 8.4 0.5 2.5 2 0 0 2 2 2 0 Clp protease DUF1631 PF07793.11 PSC76871.1 - 0.033 12.6 11.5 0.039 12.4 11.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) CTNNB1_binding PF08347.11 PSC76871.1 - 0.094 12.9 1.1 9.6 6.3 0.2 2.1 1 1 1 2 2 2 0 N-terminal CTNNB1 binding Na_H_Exchanger PF00999.21 PSC76872.1 - 1.2e-26 93.4 38.7 1.8e-26 92.9 38.7 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Acetyltransf_1 PF00583.25 PSC76873.1 - 5.7e-15 55.6 0.0 7.1e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PSC76873.1 - 5.7e-08 32.8 0.0 7.7e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PSC76873.1 - 1e-07 32.3 0.1 1.6e-07 31.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 PSC76873.1 - 1.9e-05 24.8 0.0 5.4e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 PSC76873.1 - 0.018 14.5 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Putative acetyl-transferase FR47 PF08445.10 PSC76873.1 - 0.048 13.6 0.1 0.078 13.0 0.1 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 PSC76873.1 - 0.049 13.7 0.1 0.48 10.5 0.1 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PSC76873.1 - 0.09 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 PSC76874.1 - 5.7e-15 55.6 0.0 7.1e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 PSC76874.1 - 5.7e-08 32.8 0.0 7.7e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 PSC76874.1 - 1e-07 32.3 0.1 1.6e-07 31.7 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 PSC76874.1 - 1.9e-05 24.8 0.0 5.4e-05 23.4 0.0 1.6 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 PSC76874.1 - 0.018 14.5 0.0 0.022 14.2 0.0 1.1 1 0 0 1 1 1 0 Putative acetyl-transferase FR47 PF08445.10 PSC76874.1 - 0.048 13.6 0.1 0.078 13.0 0.1 1.3 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_9 PF13527.7 PSC76874.1 - 0.049 13.7 0.1 0.48 10.5 0.1 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PSC76874.1 - 0.09 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Aldedh PF00171.22 PSC76875.1 - 1.4e-171 571.1 0.0 1.7e-171 570.8 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OPA3 PF07047.12 PSC76876.1 - 6e-23 81.0 1.0 6e-23 81.0 1.0 1.4 1 1 1 2 2 2 1 Optic atrophy 3 protein (OPA3) FAM76 PF16046.5 PSC76876.1 - 0.0035 16.8 0.5 0.004 16.6 0.5 1.1 1 0 0 1 1 1 1 FAM76 protein RIC3 PF15361.6 PSC76876.1 - 0.11 12.9 2.6 0.16 12.4 2.5 1.4 1 1 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 GST_C_2 PF13410.6 PSC76876.1 - 0.13 12.3 0.3 0.3 11.1 0.3 1.7 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Casc1_N PF15927.5 PSC76876.1 - 0.97 9.1 8.9 1.6 8.3 8.9 1.3 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus Trypsin_2 PF13365.6 PSC76877.1 - 2.3e-29 103.2 3.9 3.7e-29 102.6 3.9 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 PSC76877.1 - 1.5e-12 47.9 0.1 2.1e-12 47.3 0.1 1.2 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 PSC76877.1 - 1.2e-09 38.3 0.0 2.5e-09 37.3 0.0 1.5 1 0 0 1 1 1 1 PDZ domain PDZ_6 PF17820.1 PSC76877.1 - 8.2e-08 32.0 2.3 1.6e-05 24.6 0.3 2.6 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 PSC76877.1 - 0.00044 20.5 0.3 0.0095 16.3 0.1 2.6 2 1 0 2 2 2 1 PDZ domain Peptidase_S29 PF02907.15 PSC76877.1 - 0.0096 15.7 0.1 0.018 14.7 0.1 1.4 1 0 0 1 1 1 1 Hepatitis C virus NS3 protease Tricorn_PDZ PF14685.6 PSC76877.1 - 0.076 13.0 0.5 0.23 11.5 0.1 2.0 2 1 0 2 2 2 0 Tricorn protease PDZ domain Melibiase_2 PF16499.5 PSC76879.1 - 3.1e-150 499.1 2.5 2.4e-74 250.0 0.0 2.2 2 0 0 2 2 2 2 Alpha galactosidase A DUF4200 PF13863.6 PSC76879.1 - 1.8e-28 99.3 10.7 1.8e-28 99.3 10.7 3.4 5 0 0 5 5 1 1 Domain of unknown function (DUF4200) Melibiase_C PF17801.1 PSC76879.1 - 4e-28 97.3 0.1 1.7e-13 50.4 0.1 2.8 2 0 0 2 2 2 2 Alpha galactosidase C-terminal beta sandwich domain AAA_lid_9 PF17871.1 PSC76879.1 - 3.3e-24 84.8 0.1 3.3e-24 84.8 0.1 2.9 3 0 0 3 3 1 1 AAA lid domain AAA_2 PF07724.14 PSC76879.1 - 3.4e-20 72.9 0.0 3.3e-18 66.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA PF00004.29 PSC76879.1 - 2.9e-18 66.6 0.0 1.6e-10 41.6 0.0 3.1 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 PSC76879.1 - 1.4e-16 60.3 0.8 1.4e-16 60.3 0.8 2.3 2 0 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein Melibiase PF02065.18 PSC76879.1 - 3.6e-16 59.1 0.0 3.2e-08 32.9 0.0 2.3 2 0 0 2 2 2 2 Melibiase AAA_5 PF07728.14 PSC76879.1 - 1.9e-07 31.2 0.8 0.022 14.8 0.0 4.1 3 2 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 PSC76879.1 - 3.9e-07 30.4 0.1 0.061 13.6 0.0 3.9 2 1 1 3 3 2 2 AAA domain AAA_18 PF13238.6 PSC76879.1 - 5.8e-07 30.1 0.0 0.0021 18.6 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.6 PSC76879.1 - 3.6e-06 27.5 0.2 0.0009 19.7 0.0 9.1 7 3 1 9 9 7 2 AAA ATPase domain NACHT PF05729.12 PSC76879.1 - 1.6e-05 24.8 0.0 0.072 13.0 0.0 3.3 3 0 0 3 3 2 2 NACHT domain RuvB_N PF05496.12 PSC76879.1 - 0.00014 21.7 0.6 0.72 9.6 0.0 3.5 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain CTU2 PF10288.9 PSC76879.1 - 0.00063 20.0 0.1 0.0033 17.6 0.1 2.3 1 0 0 1 1 1 1 Cytoplasmic tRNA 2-thiolation protein 2 IstB_IS21 PF01695.17 PSC76879.1 - 0.00091 19.0 0.0 2.1 8.1 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein Sigma54_activat PF00158.26 PSC76879.1 - 0.0016 18.1 0.0 1 9.0 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_29 PF13555.6 PSC76879.1 - 0.0032 17.2 0.0 0.26 11.0 0.0 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain TniB PF05621.11 PSC76879.1 - 0.0073 15.7 0.0 0.78 9.1 0.0 3.0 2 1 0 3 3 3 1 Bacterial TniB protein NTPase_1 PF03266.15 PSC76879.1 - 0.0081 16.1 0.0 0.31 10.9 0.0 2.4 2 0 0 2 2 2 1 NTPase TsaE PF02367.17 PSC76879.1 - 0.01 15.8 0.1 1.9 8.5 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Mg_chelatase PF01078.21 PSC76879.1 - 0.029 13.8 0.2 4.7 6.5 0.0 2.7 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 PSC76879.1 - 0.037 14.1 0.0 0.89 9.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 PSC76879.1 - 0.04 14.3 0.0 4.1 7.8 0.0 2.4 2 0 0 2 2 2 0 RNA helicase DUF815 PF05673.13 PSC76879.1 - 0.051 12.7 0.0 2.9 7.0 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 PSC76879.1 - 0.073 13.0 0.0 1.4 8.8 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase TIP49 PF06068.13 PSC76879.1 - 0.075 12.2 0.1 3.2 6.9 0.0 2.4 2 0 0 2 2 2 0 TIP49 P-loop domain ATPase_2 PF01637.18 PSC76879.1 - 0.078 12.9 0.3 70 3.2 0.0 3.6 4 0 0 4 4 4 0 ATPase domain predominantly from Archaea RNA_POL_M_15KD PF02150.16 PSC76879.1 - 0.14 12.1 0.2 0.36 10.8 0.2 1.6 1 0 0 1 1 1 0 RNA polymerases M/15 Kd subunit AAA_7 PF12775.7 PSC76879.1 - 0.22 11.0 0.0 26 4.3 0.0 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region GAS PF13851.6 PSC76879.1 - 0.75 9.1 9.8 0.36 10.2 0.7 3.1 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding Prefoldin_2 PF01920.20 PSC76879.1 - 1.7 8.6 6.4 6.7 6.7 0.0 3.1 3 0 0 3 3 2 0 Prefoldin subunit FKBP_C PF00254.28 PSC76880.1 - 8.5e-19 67.7 0.0 1.2e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase PsbQ PF05757.11 PSC76880.1 - 3.9 7.2 6.3 10 5.8 6.3 1.7 1 1 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) MFS_1 PF07690.16 PSC76881.1 - 2e-20 73.0 39.0 3.6e-20 72.2 39.0 1.4 1 0 0 1 1 1 1 Major Facilitator Superfamily adh_short PF00106.25 PSC76882.1 - 7.6e-46 156.0 1.0 1e-45 155.6 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC76882.1 - 1.7e-31 109.6 1.3 1.7e-31 109.6 1.3 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC76882.1 - 9.6e-13 48.4 1.8 1e-12 48.4 0.5 1.7 1 1 1 2 2 2 1 KR domain DUF1776 PF08643.10 PSC76882.1 - 4.8e-07 29.4 0.0 7.2e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 PSC76882.1 - 4e-05 23.2 0.2 8.4e-05 22.1 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PSC76882.1 - 0.018 14.9 4.2 0.019 14.9 0.4 2.2 1 1 1 2 2 2 0 NAD(P)H-binding adh_short PF00106.25 PSC76883.1 - 9.6e-46 155.7 1.0 1.3e-45 155.3 1.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC76883.1 - 9.1e-32 110.5 0.6 1.5e-31 109.8 0.6 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC76883.1 - 1.3e-12 47.9 0.6 1.3e-12 47.9 0.6 1.6 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 PSC76883.1 - 4.8e-07 29.4 0.0 6.7e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 PSC76883.1 - 4.8e-05 22.9 0.1 9.8e-05 21.9 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PSC76883.1 - 0.0025 17.8 0.4 0.017 15.0 0.1 2.2 2 0 0 2 2 2 1 NAD(P)H-binding adh_short PF00106.25 PSC76884.1 - 7.5e-45 152.8 0.6 9.8e-45 152.4 0.6 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC76884.1 - 3.4e-30 105.3 1.2 4.9e-30 104.8 1.2 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC76884.1 - 1e-12 48.3 0.5 1e-12 48.3 0.5 1.6 2 0 0 2 2 2 1 KR domain DUF1776 PF08643.10 PSC76884.1 - 5.4e-07 29.3 0.0 8e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 PSC76884.1 - 3.9e-05 23.2 0.2 8.3e-05 22.2 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 PSC76884.1 - 0.014 15.3 3.2 0.018 14.9 0.5 2.1 1 1 1 2 2 2 0 NAD(P)H-binding Pyr_redox_2 PF07992.14 PSC76885.1 - 8.4e-43 146.7 0.0 1.1e-42 146.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PSC76885.1 - 1.8e-09 38.0 0.0 5.2e-09 36.6 0.0 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 PSC76885.1 - 0.22 11.1 1.7 0.73 9.4 0.0 2.0 1 1 1 2 2 2 0 FAD dependent oxidoreductase TPR_16 PF13432.6 PSC76886.1 - 1.1e-06 29.1 3.3 1.1e-06 29.1 3.3 2.5 2 2 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 PSC76886.1 - 3.8e-05 24.1 1.7 3.8e-05 24.1 1.7 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 PSC76886.1 - 0.00035 20.3 0.2 0.055 13.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 PSC76886.1 - 0.00089 18.9 1.0 0.017 14.8 0.0 2.7 3 0 0 3 3 3 1 TPR repeat TPR_6 PF13174.6 PSC76886.1 - 0.002 18.7 0.1 0.002 18.7 0.1 3.8 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 PSC76886.1 - 0.0039 17.5 1.6 0.013 15.8 1.5 2.0 1 1 0 1 1 1 1 Tetratricopeptide repeat BTAD PF03704.17 PSC76886.1 - 0.004 17.6 3.2 0.0061 17.0 3.2 1.4 1 0 0 1 1 1 1 Bacterial transcriptional activator domain TPR_14 PF13428.6 PSC76886.1 - 0.0068 17.1 0.2 0.0068 17.1 0.2 3.6 3 1 1 4 4 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 PSC76886.1 - 0.0074 16.3 0.0 0.0074 16.3 0.0 3.1 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_9 PF13371.6 PSC76886.1 - 0.01 16.0 2.1 0.01 16.0 2.1 3.3 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 PSC76886.1 - 0.048 13.4 3.9 0.061 13.0 3.9 1.4 1 1 0 1 1 1 0 Tetratricopeptide repeat-like domain TPR_8 PF13181.6 PSC76886.1 - 0.059 13.6 0.1 0.44 10.9 0.0 2.4 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 PSC76886.1 - 0.39 11.1 3.9 3.7 8.0 0.5 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 PSC76886.1 - 4.9 8.1 13.6 4.6 8.2 0.6 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Rhomboid PF01694.22 PSC76887.1 - 1.9e-13 50.6 8.2 3.4e-13 49.9 8.2 1.4 1 0 0 1 1 1 1 Rhomboid family Pox_A_type_inc PF04508.12 PSC76888.1 - 0.014 15.2 7.2 0.47 10.4 0.5 3.3 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat Csm1_N PF18504.1 PSC76888.1 - 0.049 14.0 0.6 0.049 14.0 0.6 12.1 10 4 4 14 14 14 0 Csm1 N-terminal domain PRA-CH PF01502.18 PSC76889.1 - 1e-29 102.2 0.0 1.9e-29 101.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosyl-AMP cyclohydrolase PRA-PH PF01503.17 PSC76889.1 - 6.3e-11 42.6 0.1 1.8e-10 41.1 0.1 1.7 1 0 0 1 1 1 1 Phosphoribosyl-ATP pyrophosphohydrolase MazG PF03819.17 PSC76889.1 - 0.0029 17.7 0.2 0.005 17.0 0.2 1.3 1 0 0 1 1 1 1 MazG nucleotide pyrophosphohydrolase domain Joubert PF15392.6 PSC76889.1 - 0.34 10.6 2.6 0.51 10.0 2.6 1.3 1 0 0 1 1 1 0 Joubert syndrome-associated DNA_pol_E_B PF04042.16 PSC76890.1 - 4.8e-33 114.3 0.0 8.5e-33 113.5 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B adh_short PF00106.25 PSC76890.1 - 2.2e-11 43.6 0.1 3.6e-11 42.9 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 PSC76890.1 - 1e-10 41.6 0.1 1.8e-10 40.8 0.1 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 PSC76890.1 - 0.0002 21.3 0.5 0.00035 20.5 0.5 1.4 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 PSC76890.1 - 0.018 14.5 0.2 0.029 13.8 0.2 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family F-box-like PF12937.7 PSC76890.1 - 0.12 12.3 0.2 0.26 11.2 0.2 1.5 1 0 0 1 1 1 0 F-box-like Lipase_GDSL_2 PF13472.6 PSC76891.1 - 1e-07 32.6 1.4 3.8e-07 30.7 0.1 2.5 2 1 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase family Oxidored_FMN PF00724.20 PSC76892.1 - 1.1e-83 281.3 0.0 1.3e-83 281.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Nup96 PF12110.8 PSC76893.1 - 1.3e-70 237.9 0.2 1.9e-70 237.3 0.2 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 PSC76893.1 - 2e-42 144.8 0.0 2.7e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nup96 PF12110.8 PSC76894.1 - 1.3e-70 237.8 0.2 1.9e-70 237.3 0.2 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 PSC76894.1 - 2e-42 144.8 0.0 2.7e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase Nup96 PF12110.8 PSC76895.1 - 1.3e-70 237.9 0.2 1.9e-70 237.3 0.2 1.2 1 0 0 1 1 1 1 Nuclear protein 96 Nucleoporin2 PF04096.14 PSC76895.1 - 2e-42 144.8 0.0 2.7e-42 144.4 0.0 1.2 1 0 0 1 1 1 1 Nucleoporin autopeptidase Metallophos PF00149.28 PSC76896.1 - 1e-12 49.0 0.0 1.6e-12 48.4 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos PF00149.28 PSC76897.1 - 7.9e-13 49.4 0.1 1.2e-12 48.8 0.1 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Ribosomal_L6 PF00347.23 PSC76898.1 - 9.4e-26 90.3 1.2 3.2e-13 50.1 0.3 3.2 3 0 0 3 3 3 2 Ribosomal protein L6 MS_channel PF00924.18 PSC76898.1 - 5.1e-09 36.0 1.0 8.1e-09 35.3 1.0 1.2 1 0 0 1 1 1 1 Mechanosensitive ion channel EF-hand_1 PF00036.32 PSC76898.1 - 0.0066 15.9 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 EF hand DUF1676 PF07898.13 PSC76898.1 - 0.11 12.6 0.2 0.32 11.0 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) PP2C PF00481.21 PSC76899.1 - 5.1e-23 82.0 0.0 1.3e-15 57.7 0.0 2.9 2 0 0 2 2 2 2 Protein phosphatase 2C FHA PF00498.26 PSC76899.1 - 3.8e-15 56.0 0.0 6e-15 55.4 0.0 1.3 1 0 0 1 1 1 1 FHA domain PHO4 PF01384.20 PSC76899.1 - 1.1e-10 41.1 0.4 1.1e-10 41.1 0.4 1.6 2 0 0 2 2 2 1 Phosphate transporter family DUF3496 PF12001.8 PSC76899.1 - 0.85 10.0 3.9 1.8 9.0 3.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3496) betaPIX_CC PF16523.5 PSC76899.1 - 2 8.3 7.3 0.43 10.5 0.5 2.5 2 0 0 2 2 2 0 betaPIX coiled coil MULE PF10551.9 PSC76900.1 - 4.9e-05 23.7 0.0 9.7e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 MULE transposase domain DUF5616 PF18481.1 PSC76900.1 - 0.15 12.4 0.0 0.27 11.6 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5616) DUF677 PF05055.12 PSC76900.1 - 0.37 9.6 1.5 0.61 8.9 1.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF677) LRR_4 PF12799.7 PSC76901.1 - 0.00095 19.5 0.5 0.36 11.3 0.1 4.5 5 0 0 5 5 5 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 PSC76901.1 - 0.017 14.8 3.8 0.046 13.5 0.4 3.2 3 0 0 3 3 3 0 Leucine rich repeat LRR_9 PF14580.6 PSC76901.1 - 0.049 13.1 0.0 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 Leucine-rich repeat Dynamin_M PF01031.20 PSC76903.1 - 5.9e-50 170.1 0.0 1.7e-49 168.5 0.0 1.7 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.23 PSC76903.1 - 2e-49 167.9 0.0 3.6e-49 167.1 0.0 1.5 1 0 0 1 1 1 1 Dynamin family GED PF02212.18 PSC76903.1 - 4.2e-17 62.1 0.5 1.1e-16 60.7 0.5 1.8 1 0 0 1 1 1 1 Dynamin GTPase effector domain Redoxin PF08534.10 PSC76903.1 - 2e-15 56.8 0.0 4.5e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Redoxin MMR_HSR1 PF01926.23 PSC76903.1 - 5.5e-05 23.2 0.0 0.00018 21.5 0.0 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_28 PF13521.6 PSC76903.1 - 0.03 14.6 0.0 0.093 13.0 0.0 1.9 1 0 0 1 1 1 0 AAA domain FKBP_C PF00254.28 PSC76904.1 - 1.7e-15 57.1 0.0 2.6e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RskA PF10099.9 PSC76904.1 - 0.19 12.0 14.8 0.37 11.1 14.8 1.4 1 0 0 1 1 1 0 Anti-sigma-K factor rskA GPP34 PF05719.11 PSC76904.1 - 0.4 10.7 6.7 0.52 10.3 6.7 1.2 1 0 0 1 1 1 0 Golgi phosphoprotein 3 (GPP34) PsbQ PF05757.11 PSC76904.1 - 5.5 6.7 9.6 12 5.6 9.6 1.6 1 1 0 1 1 1 0 Oxygen evolving enhancer protein 3 (PsbQ) ACT PF01842.25 PSC76905.1 - 1.3e-06 28.0 0.2 0.00018 21.2 0.1 2.4 2 0 0 2 2 2 2 ACT domain ACT_4 PF13291.6 PSC76905.1 - 0.00037 21.0 0.5 0.033 14.8 0.2 2.4 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.6 PSC76905.1 - 0.085 12.8 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 ACT domain NIL PF09383.10 PSC76905.1 - 0.1 12.4 0.0 0.26 11.1 0.0 1.7 1 0 0 1 1 1 0 NIL domain Pept_tRNA_hydro PF01195.19 PSC76907.1 - 8.1e-56 188.7 0.0 1.1e-55 188.2 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase Ax_dynein_light PF10211.9 PSC76908.1 - 0.00011 22.2 14.6 0.00095 19.2 0.3 3.5 3 0 0 3 3 3 2 Axonemal dynein light chain bZIP_2 PF07716.15 PSC76908.1 - 0.0065 16.5 1.3 0.0065 16.5 1.3 4.9 5 0 0 5 5 5 1 Basic region leucine zipper NYD-SP28_assoc PF14775.6 PSC76908.1 - 0.059 13.5 1.5 14 5.9 0.1 3.5 3 0 0 3 3 3 0 Sperm tail C-terminal domain WD40_alt PF14077.6 PSC76908.1 - 0.32 10.9 1.9 0.9 9.5 0.4 2.4 2 0 0 2 2 2 0 Alternative WD40 repeat motif AATF-Che1 PF13339.6 PSC76908.1 - 1.1 9.9 8.0 9 7.0 1.4 3.0 2 0 0 2 2 2 0 Apoptosis antagonizing transcription factor GAS PF13851.6 PSC76908.1 - 1.6 8.1 15.5 0.071 12.4 0.9 3.5 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding TMF_TATA_bd PF12325.8 PSC76908.1 - 1.6 9.0 21.7 0.25 11.6 3.5 4.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding Fib_alpha PF08702.10 PSC76908.1 - 3.5 7.8 7.3 2.4 8.3 2.2 2.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF3392 PF11872.8 PSC76909.1 - 0.089 13.1 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3392) Cullin PF00888.22 PSC76910.1 - 2.1e-24 86.1 0.0 3.5e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Cullin family ANAPC2 PF08672.11 PSC76910.1 - 5.5e-23 81.3 0.0 2.6e-22 79.1 0.0 2.2 2 0 0 2 2 2 1 Anaphase promoting complex (APC) subunit 2 DinB_2 PF12867.7 PSC76910.1 - 0.47 11.0 5.2 3.3 8.2 0.1 3.7 3 1 0 3 3 3 0 DinB superfamily DNA_pol_phi PF04931.13 PSC76910.1 - 5.3 5.0 4.2 8.8 4.3 4.2 1.2 1 0 0 1 1 1 0 DNA polymerase phi TPT PF03151.16 PSC76911.1 - 3.4e-09 36.5 1.0 4.3e-09 36.1 1.0 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 PSC76911.1 - 0.00049 20.3 14.2 0.073 13.2 7.0 2.2 2 0 0 2 2 2 2 EamA-like transporter family DUF2070 PF09843.9 PSC76911.1 - 0.0028 16.0 3.7 0.0032 15.8 3.7 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2070) DUF417 PF04224.12 PSC76911.1 - 0.033 13.8 1.2 0.079 12.5 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF417 Ephrin_rec_like PF07699.13 PSC76912.1 - 8.7e-25 86.2 49.5 7.3e-09 35.2 2.2 7.8 4 2 3 7 7 7 6 Putative ephrin-receptor like TNFR_c6 PF00020.18 PSC76912.1 - 2.1e-07 31.2 33.3 0.035 14.5 0.9 8.5 5 2 1 7 7 7 4 TNFR/NGFR cysteine-rich region NCD3G PF07562.14 PSC76912.1 - 2.5e-06 27.4 34.6 0.0075 16.2 2.0 7.3 5 1 0 6 6 6 5 Nine Cysteines Domain of family 3 GPCR Pkinase_Tyr PF07714.17 PSC76913.1 - 1.1e-46 159.2 0.0 2.1e-37 128.8 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PSC76913.1 - 3.7e-40 138.0 0.0 3.2e-32 111.9 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain PB1 PF00564.24 PSC76913.1 - 0.014 15.4 0.0 0.12 12.4 0.0 2.2 1 1 0 1 1 1 0 PB1 domain TRAM_LAG1_CLN8 PF03798.16 PSC76914.1 - 2.1e-34 119.0 19.9 3.2e-34 118.4 19.9 1.3 1 0 0 1 1 1 1 TLC domain TRAM_LAG1_CLN8 PF03798.16 PSC76915.1 - 2.1e-34 119.0 19.9 3.2e-34 118.4 19.9 1.3 1 0 0 1 1 1 1 TLC domain 2OG-FeII_Oxy_3 PF13640.6 PSC76917.1 - 3.4e-15 56.7 0.0 6.9e-15 55.7 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 PSC76917.1 - 2.7e-14 53.6 0.3 2.4e-13 50.6 0.3 2.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PTPRCAP PF15713.5 PSC76917.1 - 0.0088 16.3 10.3 0.013 15.8 4.3 2.8 3 0 0 3 3 3 1 Protein tyrosine phosphatase receptor type C-associated NAM-associated PF14303.6 PSC76917.1 - 0.36 11.5 7.3 0.64 10.7 7.3 1.3 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain CDC45 PF02724.14 PSC76917.1 - 1.4 7.1 7.8 2 6.6 7.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Chalcone_3 PF16036.5 PSC76918.1 - 3.5e-11 43.5 0.0 4.1e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Chalcone isomerase-like Chalcone_2 PF16035.5 PSC76918.1 - 0.00016 21.6 0.0 0.0002 21.2 0.0 1.2 1 0 0 1 1 1 1 Chalcone isomerase like Chalcone PF02431.15 PSC76918.1 - 0.001 18.5 0.0 0.0015 18.0 0.0 1.4 1 1 0 1 1 1 1 Chalcone-flavanone isomerase CdiI_4 PF18624.1 PSC76918.1 - 0.07 13.6 0.0 0.1 13.1 0.0 1.2 1 0 0 1 1 1 0 CDI immunity protein DNA_binding_1 PF01035.20 PSC76921.1 - 7e-25 87.0 1.2 1.3e-24 86.1 0.0 2.0 2 0 0 2 2 2 1 6-O-methylguanine DNA methyltransferase, DNA binding domain TFIIA PF03153.13 PSC76922.1 - 0.36 10.8 32.0 0.012 15.6 26.2 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 PSC76922.1 - 0.38 9.0 24.4 0.47 8.7 24.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CPSF100_C PF13299.6 PSC76922.1 - 2.9 8.0 11.6 4.7 7.4 11.6 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RICTOR_N PF14664.6 PSC76922.1 - 4.1 6.3 6.3 14 4.5 6.2 1.7 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term Zip PF02535.22 PSC76922.1 - 4.2 6.5 8.4 7 5.8 8.4 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter SID-1_RNA_chan PF13965.6 PSC76922.1 - 9.1 4.6 7.8 11 4.3 7.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Acetyltransf_1 PF00583.25 PSC76924.1 - 2.6e-11 43.8 0.0 3.7e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 PSC76924.1 - 3e-09 36.7 0.0 4.9e-09 36.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 PSC76924.1 - 3.4e-09 37.0 0.0 5.4e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 PSC76924.1 - 7.4e-08 32.4 0.0 1.5e-07 31.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 PSC76924.1 - 0.05 13.7 0.0 0.22 11.6 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 PSC76924.1 - 0.075 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 GNAT acetyltransferase CCDC53 PF10152.9 PSC76924.1 - 5 7.5 6.0 2.7 8.4 1.3 2.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Cellulase PF00150.18 PSC76925.1 - 1.3e-13 51.1 0.0 1.1e-12 48.0 0.0 2.1 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 PSC76925.1 - 0.00021 20.8 0.0 0.00082 18.8 0.0 1.8 1 1 0 1 1 1 1 Beta-galactosidase Resolvase PF00239.21 PSC76926.1 - 1.1e-11 45.1 0.5 1.9e-06 28.0 0.0 2.9 3 0 0 3 3 3 2 Resolvase, N terminal domain Usp PF00582.26 PSC76927.1 - 5.3e-18 65.9 8.7 2.7e-15 57.1 0.1 3.0 3 1 0 3 3 3 2 Universal stress protein family GCV_T PF01571.21 PSC76928.1 - 2.6e-09 36.8 0.0 4.9e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain Flavin_Reduct PF01613.18 PSC76929.1 - 1.8e-22 80.0 0.0 4.1e-22 78.9 0.0 1.6 1 0 0 1 1 1 1 Flavin reductase like domain Lactamase_B PF00753.27 PSC76929.1 - 4.6e-11 43.1 0.0 1.3e-10 41.6 0.0 1.7 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 PSC76929.1 - 9.1e-05 22.1 0.0 0.00019 21.0 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Exostosin PF03016.15 PSC76930.1 - 0.029 13.6 0.0 0.05 12.8 0.0 1.3 1 0 0 1 1 1 0 Exostosin family Arf PF00025.21 PSC76932.1 - 1.9e-44 151.2 0.0 2.3e-44 150.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 PSC76932.1 - 5.7e-07 29.8 0.0 1.6e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 PSC76932.1 - 1.1e-06 28.1 0.0 0.027 13.6 0.0 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 PSC76932.1 - 3.2e-05 23.6 0.0 8.1e-05 22.3 0.0 1.6 1 1 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 PSC76932.1 - 0.00048 20.2 0.0 0.00072 19.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 PSC76932.1 - 0.0024 17.3 0.0 0.003 16.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 PSC76932.1 - 0.0025 17.3 0.0 0.0069 15.8 0.0 1.7 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.6 PSC76932.1 - 0.0083 16.4 0.0 0.018 15.3 0.0 1.7 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 PSC76932.1 - 0.013 15.9 0.1 0.6 10.5 0.0 2.2 1 1 0 2 2 2 0 AAA ATPase domain Thymidylate_kin PF02223.17 PSC76932.1 - 0.15 11.7 0.1 0.22 11.2 0.1 1.2 1 0 0 1 1 1 0 Thymidylate kinase FBPase PF00316.20 PSC76933.1 - 2e-30 105.7 0.1 3e-30 105.1 0.1 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Acetyltransf_10 PF13673.7 PSC76934.1 - 3.5e-11 43.1 0.0 6e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 PSC76934.1 - 4.1e-11 43.1 0.0 6.8e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 PSC76934.1 - 4.3e-09 36.7 0.0 7.6e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 PSC76934.1 - 4.8e-06 26.5 0.0 8.1e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 PSC76934.1 - 0.0009 19.3 0.0 0.0015 18.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 PSC76934.1 - 0.0046 17.0 0.0 0.0083 16.2 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Ribosomal_S21 PF01165.20 PSC76935.1 - 7.2e-13 48.0 2.5 1.2e-12 47.3 2.5 1.4 1 0 0 1 1 1 1 Ribosomal protein S21 LCM PF04072.14 PSC76936.1 - 9.1e-09 35.5 0.1 1.8e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase p450 PF00067.22 PSC76937.1 - 3.9e-65 220.4 0.0 2e-46 158.7 0.0 2.0 2 0 0 2 2 2 2 Cytochrome P450 Fasciclin PF02469.22 PSC76938.1 - 0.017 15.4 0.0 0.022 15.0 0.0 1.3 1 0 0 1 1 1 0 Fasciclin domain RCC1 PF00415.18 PSC76939.1 - 7.9e-27 93.6 34.6 1.7e-05 25.4 0.1 7.5 6 1 1 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 PSC76939.1 - 4.9e-25 86.8 49.2 4.4e-07 29.5 0.1 8.6 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Peptidase_C1 PF00112.23 PSC76939.1 - 1.2e-15 58.2 0.0 8.5e-15 55.4 0.0 2.0 1 1 0 1 1 1 1 Papain family cysteine protease DRMBL PF07522.14 PSC76940.1 - 1.2e-23 83.4 0.0 2.3e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 PSC76940.1 - 6.8e-09 35.5 0.2 2.3e-08 33.8 0.2 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain ANAPC15 PF15243.6 PSC76940.1 - 0.0011 19.3 1.1 0.0029 18.0 1.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 15 RMMBL PF07521.12 PSC76940.1 - 0.15 12.0 0.0 1.1 9.3 0.0 2.2 2 0 0 2 2 2 0 Zn-dependent metallo-hydrolase RNA specificity domain rve PF00665.26 PSC76941.1 - 1.2e-24 86.7 0.0 2e-24 86.1 0.0 1.3 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.6 PSC76941.1 - 5.2e-05 22.9 0.0 9.2e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain MAD PF05557.13 PSC76942.1 - 2e-46 158.7 40.2 1e-45 156.3 35.7 2.8 1 1 0 1 1 1 1 Mitotic checkpoint protein TSC22 PF01166.18 PSC76942.1 - 0.047 14.0 11.4 9.2 6.7 0.3 5.6 5 0 0 5 5 5 0 TSC-22/dip/bun family DUF4201 PF13870.6 PSC76942.1 - 0.05 13.3 0.1 0.05 13.3 0.1 5.6 5 2 0 5 5 5 0 Domain of unknown function (DUF4201) BLOC1_2 PF10046.9 PSC76942.1 - 0.24 11.7 0.0 0.24 11.7 0.0 5.2 6 0 0 6 6 6 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 NPV_P10 PF05531.12 PSC76942.1 - 0.24 11.9 12.1 63 4.1 0.1 6.3 5 1 1 6 6 6 0 Nucleopolyhedrovirus P10 protein FlaC_arch PF05377.11 PSC76942.1 - 0.39 11.1 8.3 35 4.9 0.1 5.4 5 0 0 5 5 5 0 Flagella accessory protein C (FlaC) SlyX PF04102.12 PSC76942.1 - 0.42 11.3 0.0 0.42 11.3 0.0 10.8 8 3 3 11 11 11 0 SlyX ATG16 PF08614.11 PSC76942.1 - 0.49 10.6 83.3 0.18 12.0 17.5 5.0 3 2 2 5 5 5 0 Autophagy protein 16 (ATG16) TMF_DNA_bd PF12329.8 PSC76942.1 - 7.7 6.6 43.6 3 7.9 0.3 7.3 7 1 1 8 8 8 0 TATA element modulatory factor 1 DNA binding Str_synth PF03088.16 PSC76943.1 - 2.9e-19 69.0 0.0 1.2e-18 66.9 0.0 2.1 1 1 0 1 1 1 1 Strictosidine synthase SGL PF08450.12 PSC76943.1 - 6.7e-08 32.4 0.0 1.2e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region PQQ_3 PF13570.6 PSC76943.1 - 6.3 7.4 10.7 3.9 8.1 0.1 4.8 4 1 0 4 4 4 0 PQQ-like domain Str_synth PF03088.16 PSC76944.1 - 3.1e-19 68.9 0.0 1.3e-18 66.9 0.0 2.1 1 1 0 1 1 1 1 Strictosidine synthase SGL PF08450.12 PSC76944.1 - 7.3e-08 32.3 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region 7tm_1 PF00001.21 PSC76944.1 - 0.039 13.3 0.1 0.061 12.6 0.1 1.2 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) MARVEL PF01284.23 PSC76944.1 - 0.046 13.8 0.1 0.046 13.8 0.1 2.4 2 0 0 2 2 2 0 Membrane-associating domain PQQ_3 PF13570.6 PSC76944.1 - 6.6 7.4 10.5 4.1 8.0 0.1 4.8 4 1 0 4 4 4 0 PQQ-like domain SDA1 PF05285.12 PSC76945.1 - 0.0013 18.3 61.6 0.0017 17.9 61.6 1.2 1 0 0 1 1 1 1 SDA1 CCSAP PF15748.5 PSC76945.1 - 0.024 14.8 27.8 0.039 14.1 27.8 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DUF4045 PF13254.6 PSC76945.1 - 0.026 14.2 23.7 0.031 13.9 23.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Dsh_C PF12316.8 PSC76945.1 - 0.056 13.8 2.8 0.08 13.4 2.8 1.4 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Hid1 PF12722.7 PSC76945.1 - 1.3 7.0 27.3 1.6 6.8 27.3 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Endostatin PF06482.11 PSC76945.1 - 3 7.2 8.0 4.1 6.8 8.0 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SLC12 PF03522.15 PSC76945.1 - 5.7 5.9 24.2 6.9 5.6 24.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Formyl_trans_N PF00551.19 PSC76946.1 - 2.1e-33 115.6 0.0 2.6e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Formyl transferase ACT PF01842.25 PSC76946.1 - 8.2e-06 25.5 0.2 3.7e-05 23.4 0.0 2.1 2 0 0 2 2 2 1 ACT domain ACT_6 PF13740.6 PSC76946.1 - 0.011 15.7 0.0 0.023 14.7 0.0 1.7 1 1 0 1 1 1 0 ACT domain Hs1pro-1_N PF07231.12 PSC76947.1 - 2.6e-06 27.3 0.0 7.2e-06 25.9 0.0 1.7 1 0 0 1 1 1 1 Hs1pro-1 N-terminus KASH_CCD PF14662.6 PSC76947.1 - 0.0081 16.0 0.4 0.0081 16.0 0.4 5.7 4 2 3 7 7 7 2 Coiled-coil region of CCDC155 or KASH GAF PF01590.26 PSC76947.1 - 0.071 13.7 0.7 0.3 11.7 0.7 2.2 1 0 0 1 1 1 0 GAF domain DUF1664 PF07889.12 PSC76947.1 - 0.72 9.9 13.7 1.6 8.8 1.7 5.0 4 2 1 5 5 5 0 Protein of unknown function (DUF1664) Ribosomal_L9_C PF03948.14 PSC76948.1 - 1.2e-20 73.7 2.8 2.4e-20 72.8 2.8 1.4 1 0 0 1 1 1 1 Ribosomal protein L9, C-terminal domain Ribosomal_L9_N PF01281.19 PSC76948.1 - 1.6e-14 53.2 0.0 4e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain DnaJ PF00226.31 PSC76948.1 - 1.8e-07 31.1 0.0 4.6e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 DnaJ domain DUF4208 PF13907.6 PSC76948.1 - 0.098 13.1 0.2 0.2 12.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) ABC1 PF03109.16 PSC76949.1 - 1.6e-31 109.0 0.0 2.8e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 ABC1 family UPF0029 PF01205.19 PSC76951.1 - 0.055 13.8 0.0 11 6.4 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized protein family UPF0029 PvlArgDC PF01862.16 PSC76952.1 - 1.5e-24 86.7 0.0 1.7e-24 86.5 0.0 1.0 1 0 0 1 1 1 1 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Ribosomal_L34 PF00468.17 PSC76953.1 - 1.1e-18 67.0 8.6 1.8e-18 66.2 8.6 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 F-box-like PF12937.7 PSC76954.1 - 7.6e-06 25.7 2.0 1.8e-05 24.6 2.0 1.6 1 0 0 1 1 1 1 F-box-like Metallophos PF00149.28 PSC76955.1 - 3e-20 73.6 0.0 5.4e-20 72.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 PSC76955.1 - 4.3e-20 72.1 0.1 1.3e-19 70.6 0.0 1.9 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 PSC76955.1 - 4.6e-14 53.0 0.1 6.5e-09 36.5 0.0 2.7 2 0 0 2 2 2 2 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 PSC76955.1 - 0.00068 19.9 0.0 0.019 15.1 0.0 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain fn3 PF00041.21 PSC76955.1 - 0.011 16.1 0.6 6.4 7.2 0.0 2.7 2 0 0 2 2 2 0 Fibronectin type III domain Proteasome PF00227.26 PSC76956.1 - 3.9e-56 189.6 0.0 6.3e-56 188.9 0.0 1.4 1 0 0 1 1 1 1 Proteasome subunit Peptidase_M28 PF04389.17 PSC76956.1 - 3.7e-32 111.6 0.0 6e-32 110.9 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M28 Proteasome_A_N PF10584.9 PSC76956.1 - 1.1e-13 50.5 0.1 3.1e-13 49.1 0.1 1.8 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Cupin_1 PF00190.22 PSC76956.1 - 2.5e-10 40.2 0.4 5.5e-10 39.1 0.4 1.5 1 0 0 1 1 1 1 Cupin Cupin_2 PF07883.11 PSC76956.1 - 6.5e-05 22.6 0.2 0.00049 19.8 0.2 2.4 1 1 0 1 1 1 1 Cupin domain GST_C_2 PF13410.6 PSC76956.1 - 0.0012 18.9 0.0 0.0032 17.4 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Peptidase_M20 PF01546.28 PSC76956.1 - 0.0095 15.6 0.0 0.029 14.1 0.0 1.8 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 Pkinase_Tyr PF07714.17 PSC76957.1 - 3.1e-41 141.4 0.0 1.2e-34 119.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 PSC76957.1 - 5.9e-37 127.5 0.0 3.5e-29 102.0 0.0 2.7 3 0 0 3 3 3 2 Protein kinase domain Kdo PF06293.14 PSC76957.1 - 0.038 13.3 0.0 0.069 12.5 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kelch_4 PF13418.6 PSC76958.1 - 3.9e-30 103.6 10.8 7.6e-09 35.5 0.0 6.9 5 2 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 PSC76958.1 - 5.1e-27 93.6 6.1 1.9e-06 28.0 0.0 7.7 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.6 PSC76958.1 - 7.1e-27 92.9 0.0 0.0011 18.9 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 PSC76958.1 - 4.5e-23 80.7 0.4 9.1e-06 25.8 0.0 6.3 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 PSC76958.1 - 1.6e-18 66.0 3.2 9.4e-07 28.3 0.2 5.4 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.15 PSC76958.1 - 1.2e-15 56.8 11.6 0.00012 21.9 0.0 6.8 6 2 0 6 6 6 3 Kelch motif RINGv PF12906.7 PSC76959.1 - 1.7e-06 28.0 4.8 3.2e-06 27.2 4.8 1.5 1 0 0 1 1 1 1 RING-variant domain Colicin_V PF02674.16 PSC76959.1 - 0.012 15.5 2.3 0.022 14.7 2.3 1.4 1 0 0 1 1 1 0 Colicin V production protein Glyco_hydro_16 PF00722.21 PSC76960.1 - 1.1e-16 60.8 0.0 1.9e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 PSC76960.1 - 0.0017 16.8 0.0 0.013 13.9 0.0 2.0 2 0 0 2 2 2 1 Beta-glucan synthesis-associated protein (SKN1) PhyH PF05721.13 PSC76961.1 - 1.7e-13 51.3 0.0 2.2e-13 50.9 0.0 1.2 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) MS_channel PF00924.18 PSC76963.1 - 5.6e-22 78.3 0.0 1.1e-21 77.3 0.0 1.5 1 0 0 1 1 1 1 Mechanosensitive ion channel MS_channel PF00924.18 PSC76964.1 - 3.4e-19 69.2 1.9 6.7e-19 68.3 1.9 1.4 1 0 0 1 1 1 1 Mechanosensitive ion channel Pyr_redox_2 PF07992.14 PSC76965.1 - 5.2e-54 183.5 0.1 8.9e-54 182.7 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 PSC76965.1 - 8.7e-17 61.5 0.2 2e-15 57.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rhodanese PF00581.20 PSC76965.1 - 1.3e-10 41.8 0.0 7.3e-10 39.3 0.0 2.2 2 0 0 2 2 2 1 Rhodanese-like domain WD40 PF00400.32 PSC76965.1 - 3.3e-07 30.9 4.6 0.67 10.9 0.0 6.7 7 0 0 7 7 7 2 WD domain, G-beta repeat Pyr_redox_dim PF02852.22 PSC76965.1 - 2.7e-05 24.4 0.1 7.2e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain NAD_binding_8 PF13450.6 PSC76965.1 - 0.0036 17.5 13.3 0.0039 17.4 0.2 5.4 6 0 0 6 6 6 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 PSC76965.1 - 0.016 14.5 0.0 0.31 10.2 0.0 2.4 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 PSC76965.1 - 0.048 13.7 6.8 8 6.4 0.3 4.1 2 2 1 4 4 4 0 FAD-NAD(P)-binding CW_binding_2 PF04122.12 PSC76965.1 - 0.37 11.5 3.3 3.2 8.5 3.3 2.7 1 0 0 1 1 1 0 Putative cell wall binding repeat 2 OKR_DC_1 PF01276.20 PSC76966.1 - 4.5e-60 203.5 0.0 2.5e-59 201.1 0.0 1.8 1 1 0 1 1 1 1 Orn/Lys/Arg decarboxylase, major domain OKR_DC_1_C PF03711.15 PSC76966.1 - 2.4e-08 34.4 0.0 4.9e-08 33.3 0.0 1.5 1 0 0 1 1 1 1 Orn/Lys/Arg decarboxylase, C-terminal domain Aminotran_1_2 PF00155.21 PSC76966.1 - 1.4e-06 27.7 0.3 3e-06 26.7 0.3 1.5 1 1 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 PSC76966.1 - 0.00045 19.6 3.7 0.001 18.5 3.7 1.5 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SepSecS PF05889.13 PSC76966.1 - 0.00082 18.2 0.0 0.0012 17.6 0.0 1.2 1 0 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Aminotran_5 PF00266.19 PSC76966.1 - 0.012 14.6 0.4 0.027 13.4 0.1 1.7 2 1 0 2 2 2 0 Aminotransferase class-V Sporozoite_P67 PF05642.11 PSC76966.1 - 0.059 11.5 5.7 0.072 11.2 5.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Cys_Met_Meta_PP PF01053.20 PSC76966.1 - 0.088 11.3 0.0 0.15 10.6 0.0 1.5 2 0 0 2 2 2 0 Cys/Met metabolism PLP-dependent enzyme SPX PF03105.19 PSC76966.1 - 0.12 12.3 2.7 0.14 12.0 2.7 1.1 1 0 0 1 1 1 0 SPX domain Pyridoxal_deC PF00282.19 PSC76966.1 - 0.18 10.5 0.1 0.27 9.9 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Macoilin PF09726.9 PSC76966.1 - 0.95 7.9 4.8 1.2 7.6 4.8 1.1 1 0 0 1 1 1 0 Macoilin family Apt1 PF10351.9 PSC76966.1 - 3.3 6.4 5.6 4.4 6.0 5.6 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Ctr PF04145.15 PSC76967.1 - 7e-32 111.1 0.0 1e-31 110.6 0.0 1.2 1 0 0 1 1 1 1 Ctr copper transporter family MFS_1 PF07690.16 PSC76968.1 - 1.9e-17 63.2 38.3 1.9e-17 63.2 38.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 PSC76968.1 - 3.5e-05 22.9 3.4 5.7e-05 22.2 3.4 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1_like PF12832.7 PSC76968.1 - 7.2 5.4 17.8 0.74 8.6 5.0 2.6 2 1 0 2 2 2 0 MFS_1 like family DEAD PF00270.29 PSC76969.1 - 1.8e-38 132.1 0.3 9.5e-38 129.7 0.3 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 PSC76969.1 - 5.9e-28 97.4 0.0 1.5e-27 96.2 0.0 1.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 PSC76969.1 - 0.0034 17.4 0.0 0.0085 16.1 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 PSC76969.1 - 0.03 14.6 0.0 0.19 12.0 0.0 2.4 1 1 0 1 1 1 0 AAA domain DNA_pol_phi PF04931.13 PSC76969.1 - 9.3 4.2 18.4 0.32 9.0 11.2 2.0 2 0 0 2 2 2 0 DNA polymerase phi PHO4 PF01384.20 PSC76970.1 - 6.8e-113 377.1 24.0 8.8e-113 376.8 24.0 1.1 1 0 0 1 1 1 1 Phosphate transporter family TPR_12 PF13424.6 PSC76970.1 - 6.6e-18 64.8 5.3 5.2e-10 39.5 0.3 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat Trypsin PF00089.26 PSC76970.1 - 1.9e-14 54.0 0.0 3.1e-14 53.3 0.0 1.3 1 0 0 1 1 1 1 Trypsin TPR_10 PF13374.6 PSC76970.1 - 1.5e-12 46.9 1.9 1.5e-07 31.0 0.1 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 PSC76970.1 - 1.2e-06 28.1 0.3 3.6e-05 23.5 0.1 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 PSC76970.1 - 1.1e-05 25.2 0.3 0.015 15.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 PSC76970.1 - 0.0031 17.3 0.0 0.024 14.4 0.0 2.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 PSC76970.1 - 0.01 16.6 1.1 0.081 13.8 0.2 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 PSC76970.1 - 0.07 13.3 3.7 0.054 13.6 1.4 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 PSC76970.1 - 1.8 9.4 6.2 4.6 8.2 0.1 3.4 3 0 0 3 3 2 0 Tetratricopeptide repeat LapA_dom PF06305.11 PSC76970.1 - 3.6 7.5 9.7 25 4.8 0.2 4.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain Rubrerythrin PF02915.17 PSC76971.1 - 7.4e-35 120.3 0.0 1.4e-34 119.5 0.0 1.5 1 0 0 1 1 1 1 Rubrerythrin Ferritin_2 PF13668.6 PSC76971.1 - 0.0095 16.1 0.0 2.3 8.4 0.0 2.4 2 0 0 2 2 2 2 Ferritin-like domain AurF PF11583.8 PSC76971.1 - 0.019 14.2 0.0 1.3 8.2 0.0 2.5 2 0 0 2 2 2 0 P-aminobenzoate N-oxygenase AurF FA_desaturase_2 PF03405.14 PSC76971.1 - 0.084 11.7 0.0 5 5.9 0.0 2.1 2 0 0 2 2 2 0 Fatty acid desaturase CPSF_A PF03178.15 PSC76972.1 - 1.7e-51 175.5 0.0 4e-51 174.2 0.0 1.6 1 1 0 1 1 1 1 CPSF A subunit region MMS1_N PF10433.9 PSC76972.1 - 7e-28 97.5 0.0 2.8e-27 95.5 0.0 2.0 1 1 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Macro PF01661.21 PSC76972.1 - 0.032 14.3 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 Macro domain UIM PF02809.20 PSC76973.1 - 4e-05 23.2 10.2 4.1e-05 23.2 5.4 2.5 2 0 0 2 2 2 1 Ubiquitin interaction motif TFIIA PF03153.13 PSC76973.1 - 0.024 14.6 12.6 0.025 14.6 12.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 PSC76973.1 - 0.46 9.2 3.6 0.46 9.2 3.6 1.1 1 0 0 1 1 1 0 Presenilin Spt20 PF12090.8 PSC76973.1 - 1.1 8.8 15.8 1.4 8.4 15.8 1.1 1 0 0 1 1 1 0 Spt20 family PAT1 PF09770.9 PSC76973.1 - 1.6 6.9 12.9 1.8 6.7 12.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ASFV_J13L PF05568.11 PSC76973.1 - 1.9 8.2 5.5 0.66 9.7 2.8 1.6 1 1 0 1 1 1 0 African swine fever virus J13L protein GREB1 PF15782.5 PSC76973.1 - 2.2 5.3 4.2 2.4 5.2 4.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Suf PF05843.14 PSC76973.1 - 5.4 6.9 9.5 6.9 6.6 9.5 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) NHL PF01436.21 PSC76974.1 - 3.8e-14 51.9 0.5 2.1e-05 24.3 0.0 4.4 4 0 0 4 4 4 3 NHL repeat RAP PF08373.10 PSC76974.1 - 9.4e-14 51.3 0.0 1.7e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 RAP domain FAST_1 PF06743.15 PSC76974.1 - 1.2e-08 34.7 0.1 0.00089 19.2 0.0 3.5 3 0 0 3 3 3 2 FAST kinase-like protein, subdomain 1 MTES_1575 PF18741.1 PSC76974.1 - 1.6e-06 28.2 0.0 4.5e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 REase_MTES_1575 SGL PF08450.12 PSC76974.1 - 0.00044 19.9 0.0 0.39 10.3 0.1 3.1 2 1 1 3 3 3 1 SMP-30/Gluconolactonase/LRE-like region SBBP PF06739.11 PSC76974.1 - 0.0031 17.5 0.0 1.5 8.9 0.1 2.5 2 0 0 2 2 2 2 Beta-propeller repeat CDC45 PF02724.14 PSC76974.1 - 0.75 8.0 17.0 1.2 7.4 17.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 PSC76974.1 - 1.3 7.1 25.7 2 6.4 25.7 1.2 1 0 0 1 1 1 0 DNA polymerase phi BSP_II PF05432.11 PSC76974.1 - 1.6 8.4 21.0 2.6 7.7 21.0 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Myc_N PF01056.18 PSC76974.1 - 3.2 7.6 10.5 7.2 6.4 10.5 1.6 1 0 0 1 1 1 0 Myc amino-terminal region Vfa1 PF08432.10 PSC76974.1 - 4.9 7.4 12.9 11 6.4 12.9 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Radical_SAM PF04055.21 PSC76975.1 - 2.5e-28 99.5 0.2 5.3e-28 98.5 0.1 1.6 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 PSC76975.1 - 3.5e-28 97.5 0.0 7e-28 96.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 PSC76975.1 - 2.2e-08 33.9 0.0 4.5e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 TRAM domain Lipase_GDSL_2 PF13472.6 PSC76975.1 - 0.0031 17.9 0.0 0.013 15.9 0.0 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family TRAM_2 PF18693.1 PSC76975.1 - 0.065 13.4 0.0 0.27 11.4 0.0 2.1 1 1 0 1 1 1 0 TRAM domain MFS_1 PF07690.16 PSC76976.1 - 6.2e-44 150.4 72.2 6.9e-43 146.9 53.9 1.7 1 1 1 2 2 2 2 Major Facilitator Superfamily YqfQ PF14181.6 PSC76976.1 - 2 8.6 4.1 0.34 11.1 0.4 1.5 2 0 0 2 2 2 0 YqfQ-like protein Peptidase_S8 PF00082.22 PSC76977.1 - 4.8e-38 131.1 3.0 4.8e-38 131.1 3.0 1.5 2 0 0 2 2 2 1 Subtilase family DEC-1_N PF04625.13 PSC76977.1 - 6.2 5.7 17.0 0.054 12.5 8.1 1.9 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region SOUL PF04832.12 PSC76979.1 - 5.4e-37 127.5 0.1 6.1e-37 127.4 0.1 1.0 1 0 0 1 1 1 1 SOUL heme-binding protein CDP-OH_P_transf PF01066.21 PSC76980.1 - 1e-12 48.6 1.6 1e-12 48.6 1.6 2.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase PolyA_pol PF01743.20 PSC76981.1 - 2.5e-30 105.5 0.0 3.3e-30 105.1 0.0 1.2 1 0 0 1 1 1 1 Poly A polymerase head domain E3_UbLigase_EDD PF11547.8 PSC76981.1 - 0.076 12.7 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 E3 ubiquitin ligase EDD A_deaminase PF00962.22 PSC76982.1 - 5.3e-40 137.7 0.0 6.3e-40 137.5 0.0 1.1 1 0 0 1 1 1 1 Adenosine/AMP deaminase Amidohydro_2 PF04909.14 PSC76982.1 - 0.01 15.6 0.1 0.014 15.2 0.1 1.3 1 0 0 1 1 1 0 Amidohydrolase Frankia_peptide PF14407.6 PSC76982.1 - 0.021 14.8 0.3 0.054 13.5 0.3 1.6 1 0 0 1 1 1 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. Amidohydro_1 PF01979.20 PSC76982.1 - 0.066 12.5 0.1 0.16 11.3 0.1 1.7 2 1 0 2 2 2 0 Amidohydrolase family Asparaginase PF00710.20 PSC76983.1 - 9e-16 58.0 0.0 1.5e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 PSC76983.1 - 9.1e-06 25.9 0.0 1.7e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain Spt20 PF12090.8 PSC76983.1 - 7 6.2 7.7 9.5 5.8 7.7 1.1 1 0 0 1 1 1 0 Spt20 family ChaC PF04752.12 PSC76984.1 - 1.9e-49 168.1 0.0 2.4e-49 167.8 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein Rhodanese PF00581.20 PSC76985.1 - 2.1e-07 31.4 0.1 8.1e-07 29.5 0.1 2.0 1 1 0 1 1 1 1 Rhodanese-like domain SHOCT PF09851.9 PSC76985.1 - 0.0011 18.6 0.2 0.0041 16.8 0.2 2.1 1 0 0 1 1 1 1 Short C-terminal domain Ribosomal_L27A PF00828.19 PSC76987.1 - 1.3e-30 106.7 0.4 1.9e-30 106.2 0.4 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A RWP-RK PF02042.15 PSC76988.1 - 4.9e-18 64.9 0.0 6.3e-09 35.7 0.0 2.8 2 0 0 2 2 2 2 RWP-RK domain DUF4363 PF14276.6 PSC76988.1 - 0.044 13.9 0.4 4.9 7.3 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) DUF496 PF04363.12 PSC76988.1 - 0.15 12.1 0.1 5.5 7.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF496) Methyltransf_24 PF13578.6 PSC76989.1 - 3.2e-12 47.4 0.0 5.4e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CTP_transf_1 PF01148.20 PSC76990.1 - 7.5e-72 242.3 16.5 1e-71 241.8 16.5 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family XPG_I PF00867.18 PSC76990.1 - 1e-14 54.6 0.0 1.9e-14 53.8 0.0 1.5 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 PSC76990.1 - 0.039 14.4 0.0 0.1 13.1 0.0 1.7 1 1 0 1 1 1 0 XPG N-terminal domain Peptidase_S41 PF03572.18 PSC76991.1 - 1.4e-48 164.6 0.1 1.9e-48 164.2 0.1 1.2 1 0 0 1 1 1 1 Peptidase family S41 PDZ_6 PF17820.1 PSC76991.1 - 1.6e-14 53.5 0.2 6.7e-14 51.5 0.2 2.1 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.24 PSC76991.1 - 2.4e-09 37.4 0.1 5.5e-09 36.3 0.1 1.6 1 0 0 1 1 1 1 PDZ domain PDZ_2 PF13180.6 PSC76991.1 - 8.3e-09 35.7 0.1 6.2e-08 32.8 0.0 2.4 3 0 0 3 3 3 1 PDZ domain Tricorn_PDZ PF14685.6 PSC76991.1 - 0.00024 21.0 0.1 0.0014 18.5 0.0 2.3 2 0 0 2 2 2 1 Tricorn protease PDZ domain Tricorn_C1 PF14684.6 PSC76991.1 - 0.0024 17.9 0.0 0.0041 17.2 0.0 1.3 1 0 0 1 1 1 1 Tricorn protease C1 domain RVT_1 PF00078.27 PSC76992.1 - 6.9e-27 94.4 0.0 5.7e-25 88.1 0.0 2.1 1 1 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) LamB_YcsF PF03746.16 PSC76992.1 - 0.17 11.5 1.5 0.32 10.6 1.5 1.4 1 0 0 1 1 1 0 LamB/YcsF family Methyltransf_3 PF01596.17 PSC76995.1 - 1.7e-66 223.4 0.0 2.3e-66 223.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 PSC76995.1 - 7e-15 55.9 0.0 1.3e-14 55.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 PSC76995.1 - 0.0012 19.5 0.0 0.0025 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 PSC76995.1 - 0.0014 18.4 0.0 0.0024 17.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain RRM_1 PF00076.22 PSC76996.1 - 2e-40 136.4 0.0 5.9e-20 70.9 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 PSC76996.1 - 7.9e-05 22.6 0.0 0.26 11.4 0.0 2.3 2 0 0 2 2 2 2 RNA binding motif Nup35_RRM_2 PF14605.6 PSC76996.1 - 0.0085 16.1 0.0 0.81 9.7 0.0 2.3 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif LRR_8 PF13855.6 PSC76997.1 - 3.8e-06 26.6 1.5 1.7 8.5 0.1 4.7 4 0 0 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 PSC76997.1 - 0.079 13.4 10.5 2.9 8.5 0.2 6.6 5 3 2 7 7 7 0 Leucine Rich repeats (2 copies) Kinesin PF00225.23 PSC76999.1 - 1.7e-103 346.0 1.8 2.4e-103 345.5 1.8 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PSC76999.1 - 4.9e-45 153.1 0.0 8.5e-45 152.3 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Pkinase PF00069.25 PSC76999.1 - 7.4e-38 130.4 0.0 2.2e-37 128.8 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC76999.1 - 6.3e-32 110.9 0.0 1.7e-31 109.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase CH PF00307.31 PSC76999.1 - 7.4e-12 45.4 0.0 1.5e-11 44.5 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain LRR_8 PF13855.6 PSC76999.1 - 1.2e-09 37.8 1.5 0.00054 19.7 0.3 4.9 4 1 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 PSC76999.1 - 6.1e-06 26.5 3.4 0.26 11.7 0.1 5.5 5 1 1 7 7 6 1 Leucine Rich repeats (2 copies) FlaC_arch PF05377.11 PSC76999.1 - 0.13 12.7 0.8 0.33 11.4 0.0 2.1 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) YabA PF06156.13 PSC76999.1 - 0.22 12.2 6.6 4.7 7.9 0.0 4.5 4 1 0 5 5 4 0 Initiation control protein YabA ERM PF00769.19 PSC76999.1 - 2.7 7.8 40.5 0.016 15.1 24.4 2.4 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF2009 PF09418.10 PSC76999.1 - 6.6 5.7 6.0 5.6 5.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2009) Kinesin PF00225.23 PSC77000.1 - 1.6e-103 346.2 1.8 2.2e-103 345.7 1.8 1.2 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 PSC77000.1 - 4.4e-45 153.3 0.0 7.9e-45 152.4 0.0 1.4 1 0 0 1 1 1 1 Microtubule binding Pkinase PF00069.25 PSC77000.1 - 6.5e-38 130.6 0.0 2.1e-37 129.0 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 PSC77000.1 - 5.5e-32 111.1 0.0 1.5e-31 109.6 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase CH PF00307.31 PSC77000.1 - 6.7e-12 45.6 0.0 1.4e-11 44.6 0.0 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain LRR_8 PF13855.6 PSC77000.1 - 8.6e-10 38.2 1.4 0.00051 19.8 0.3 5.0 4 1 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.7 PSC77000.1 - 2.2e-06 27.9 2.4 0.25 11.8 0.1 5.6 5 1 1 7 7 6 1 Leucine Rich repeats (2 copies) FlaC_arch PF05377.11 PSC77000.1 - 0.084 13.3 0.4 0.31 11.5 0.0 2.2 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) YabA PF06156.13 PSC77000.1 - 0.15 12.7 6.5 4.3 8.0 0.0 4.6 4 1 0 5 5 4 0 Initiation control protein YabA ERM PF00769.19 PSC77000.1 - 2.3 8.0 40.5 0.014 15.2 24.4 2.5 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF2009 PF09418.10 PSC77000.1 - 6.5 5.7 6.2 5.2 6.0 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2009) Codanin-1_C PF15296.6 PSC77001.1 - 1.9e-27 95.7 0.0 1.9e-27 95.7 0.0 4.3 4 1 0 4 4 4 1 Codanin-1 C-terminus SET PF00856.28 PSC77001.1 - 5.6e-15 56.1 0.0 5.6e-15 56.1 0.0 3.2 3 2 0 3 3 3 1 SET domain Rubis-subs-bind PF09273.11 PSC77001.1 - 0.0053 17.5 0.0 0.0053 17.5 0.0 2.7 3 0 0 3 3 3 1 Rubisco LSMT substrate-binding MafB19-deam PF14437.6 PSC77002.1 - 4.5e-27 94.5 0.0 2.5e-26 92.0 0.0 1.9 2 0 0 2 2 2 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 PSC77002.1 - 1.8e-25 88.7 0.1 2.6e-25 88.2 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 PSC77002.1 - 2.6e-06 27.6 2.2 0.004 17.2 0.2 2.4 1 1 1 2 2 2 2 Bd3614-like deaminase SNAD4 PF18750.1 PSC77002.1 - 0.023 14.8 0.0 0.033 14.3 0.0 1.2 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 APOBEC3 PF18771.1 PSC77002.1 - 0.07 13.2 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 APOBEC3 APOBEC2 PF18772.1 PSC77002.1 - 0.073 13.1 0.0 0.1 12.7 0.0 1.1 1 0 0 1 1 1 0 APOBEC2 APOBEC_N PF08210.11 PSC77002.1 - 0.13 12.1 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 APOBEC-like N-terminal domain PEP-utilisers_N PF05524.13 PSC77003.1 - 0.048 13.8 0.5 0.18 11.9 0.1 2.2 2 1 0 2 2 2 0 PEP-utilising enzyme, N-terminal Pro_isomerase PF00160.21 PSC77004.1 - 1.3e-43 149.1 0.0 2.4e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD AMP-binding PF00501.28 PSC77005.1 - 3.3e-105 352.1 0.1 4.5e-105 351.7 0.1 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 PSC77005.1 - 2.2e-16 60.6 0.0 6.7e-16 59.0 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain LpxK PF02606.14 PSC77006.1 - 4.3e-54 183.8 0.1 1.7e-52 178.6 0.1 2.3 1 1 0 1 1 1 1 Tetraacyldisaccharide-1-P 4'-kinase Glycos_transf_2 PF00535.26 PSC77006.1 - 2.3e-34 118.6 0.0 7e-34 117.1 0.0 1.8 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 PSC77006.1 - 8.8e-16 58.5 0.0 2.1e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 PSC77006.1 - 2.1e-08 33.9 0.0 5.9e-08 32.4 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 PSC77006.1 - 0.0044 16.5 0.0 0.0069 15.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 PSC77006.1 - 0.048 13.6 0.0 0.086 12.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Glyco_transf_7N PF13733.6 PSC77006.1 - 0.065 12.9 0.0 2 8.0 0.0 2.3 2 0 0 2 2 2 0 N-terminal region of glycosyl transferase group 7 AP2 PF00847.20 PSC77007.1 - 6.9e-14 51.8 14.9 1.1e-08 35.2 1.3 3.4 3 0 0 3 3 3 3 AP2 domain UCH PF00443.29 PSC77008.1 - 4e-57 193.6 0.0 6.4e-57 193.0 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 PSC77008.1 - 8.3e-31 107.8 0.2 7.3e-30 104.7 0.2 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 PSC77008.1 - 0.064 12.7 10.4 0.25 10.8 1.7 3.2 4 0 0 4 4 4 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase SUIM_assoc PF16619.5 PSC77008.1 - 0.12 12.5 2.7 0.3 11.2 2.7 1.7 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Phage_GPO PF05929.11 PSC77008.1 - 1.3 8.6 7.8 6.7 6.2 3.8 2.2 2 0 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase BAF1_ABF1 PF04684.13 PSC77008.1 - 3.9 6.4 4.8 5.8 5.8 4.8 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor LRR_4 PF12799.7 PSC77010.1 - 6e-07 29.7 10.3 0.19 12.2 0.1 6.1 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) F-box-like PF12937.7 PSC77010.1 - 0.00012 21.9 2.6 0.00047 20.0 2.6 2.1 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 PSC77010.1 - 0.0009 19.0 17.1 0.11 12.3 2.7 5.1 4 3 1 5 5 5 2 Leucine rich repeat LRR_1 PF00560.33 PSC77010.1 - 3.5 8.5 5.0 23 6.0 0.0 4.5 5 0 0 5 5 5 0 Leucine Rich Repeat Adaptin_N PF01602.20 PSC77011.1 - 2.5e-134 448.7 0.0 3e-134 448.5 0.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region tRNA-synt_1b PF00579.25 PSC77011.1 - 9.7e-84 281.1 0.0 1.5e-83 280.6 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Alpha_adaptinC2 PF02883.20 PSC77011.1 - 4e-23 81.9 0.0 6.4e-23 81.2 0.0 1.4 1 0 0 1 1 1 1 Adaptin C-terminal domain Cnd1 PF12717.7 PSC77011.1 - 7.7e-10 39.0 3.2 0.00018 21.6 0.0 2.6 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 PSC77011.1 - 0.014 15.8 16.7 0.26 11.7 0.4 5.1 5 0 0 5 5 5 0 HEAT repeats Proteasom_PSMB PF10508.9 PSC77011.1 - 0.12 10.9 3.1 0.093 11.2 0.8 1.8 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit HEAT PF02985.22 PSC77011.1 - 3.7 8.1 12.2 35 5.0 0.0 5.4 5 0 0 5 5 5 0 HEAT repeat SPC25 PF06703.11 PSC77014.1 - 2.1e-30 105.7 0.0 2.5e-30 105.4 0.0 1.1 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Pkinase_Tyr PF07714.17 PSC77015.1 - 1.9e-51 174.9 0.0 2.6e-51 174.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 PSC77015.1 - 1.2e-46 159.2 0.0 2.2e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Miff PF05644.11 PSC77015.1 - 1.7 8.2 6.9 3.8 7.1 6.9 1.5 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Presenilin PF01080.17 PSC77015.1 - 2.1 7.0 5.5 4 6.1 5.5 1.4 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 PSC77015.1 - 5.7 6.9 6.7 17 5.4 6.7 1.7 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TFIIA PF03153.13 PSC77015.1 - 6 6.7 38.6 0.045 13.8 17.7 2.8 3 0 0 3 3 3 0 Transcription factor IIA, alpha/beta subunit Pectate_lyase_3 PF12708.7 PSC77016.1 - 1.5e-29 103.4 3.2 5.7e-14 52.5 0.0 3.4 4 0 0 4 4 4 2 Pectate lyase superfamily protein Gal_Lectin PF02140.18 PSC77016.1 - 2.9e-06 27.6 0.2 8.5e-06 26.1 0.2 1.8 1 0 0 1 1 1 1 Galactose binding lectin domain Chitin_bind_1 PF00187.19 PSC77016.1 - 0.00014 22.2 17.5 0.00038 20.9 17.5 1.8 1 0 0 1 1 1 1 Chitin recognition protein Beta_helix PF13229.6 PSC77016.1 - 0.00077 19.3 0.7 0.58 10.0 0.1 2.5 2 0 0 2 2 2 2 Right handed beta helix region LTXXQ PF07813.12 PSC77016.1 - 0.042 14.6 0.3 0.042 14.6 0.3 3.1 3 0 0 3 3 3 0 LTXXQ motif family protein Pectinesterase PF01095.19 PSC77016.1 - 0.056 12.2 0.0 2 7.1 0.0 2.2 2 0 0 2 2 2 0 Pectinesterase NosD PF05048.13 PSC77016.1 - 0.13 11.5 0.0 4.8 6.4 0.0 2.2 2 0 0 2 2 2 0 Periplasmic copper-binding protein (NosD) Pectate_lyase_3 PF12708.7 PSC77017.1 - 1.5e-29 103.4 3.2 5.8e-14 52.5 0.0 3.4 4 0 0 4 4 4 2 Pectate lyase superfamily protein Gal_Lectin PF02140.18 PSC77017.1 - 3e-06 27.6 0.2 8.6e-06 26.1 0.2 1.8 1 0 0 1 1 1 1 Galactose binding lectin domain Chitin_bind_1 PF00187.19 PSC77017.1 - 0.00015 22.2 17.5 0.00039 20.8 17.5 1.8 1 0 0 1 1 1 1 Chitin recognition protein Beta_helix PF13229.6 PSC77017.1 - 0.0008 19.3 0.7 0.59 10.0 0.1 2.5 2 0 0 2 2 2 2 Right handed beta helix region LTXXQ PF07813.12 PSC77017.1 - 0.043 14.6 0.3 0.043 14.6 0.3 3.3 4 0 0 4 4 4 0 LTXXQ motif family protein Pectinesterase PF01095.19 PSC77017.1 - 0.057 12.1 0.0 2 7.0 0.0 2.2 2 0 0 2 2 2 0 Pectinesterase NosD PF05048.13 PSC77017.1 - 0.13 11.5 0.0 4.9 6.3 0.0 2.2 2 0 0 2 2 2 0 Periplasmic copper-binding protein (NosD) zf-MYND PF01753.18 PSC77018.1 - 2.5e-08 33.9 7.9 2.5e-08 33.9 7.9 2.9 3 0 0 3 3 3 1 MYND finger zf-C6H2 PF15801.5 PSC77018.1 - 0.075 13.4 5.3 0.19 12.0 5.3 1.8 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding MRP-L28 PF09812.9 PSC77018.1 - 0.35 11.0 6.7 0.68 10.1 6.7 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L28 Spt20 PF12090.8 PSC77018.1 - 1.2 8.6 8.2 1.8 8.1 8.2 1.2 1 0 0 1 1 1 0 Spt20 family FMN_dh PF01070.18 PSC77019.1 - 1.5e-39 136.0 0.0 1.5e-39 136.0 0.0 3.1 4 0 0 4 4 4 1 FMN-dependent dehydrogenase ARID PF01388.21 PSC77019.1 - 2.1e-14 54.0 3.2 2.4e-14 53.8 0.0 2.5 2 1 0 2 2 2 1 ARID/BRIGHT DNA binding domain LINES_C PF14695.6 PSC77019.1 - 0.19 11.2 0.1 0.19 11.2 0.1 1.9 2 0 0 2 2 2 0 Lines C-terminus Lin-8 PF03353.15 PSC77019.1 - 9.3 5.7 34.0 0.24 10.9 2.7 2.5 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist ELMO_CED12 PF04727.13 PSC77020.1 - 5.4e-11 42.9 1.2 8.7e-11 42.2 0.0 1.9 2 0 0 2 2 2 1 ELMO/CED-12 family DUF1490 PF07371.12 PSC77020.1 - 0.032 14.3 1.8 0.22 11.6 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1490) DUF2052 PF09747.9 PSC77020.1 - 0.4 10.8 16.0 2.3 8.3 3.0 2.2 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) Presenilin PF01080.17 PSC77020.1 - 9.3 4.9 14.5 2.8 6.6 6.8 2.1 2 0 0 2 2 2 0 Presenilin Ank_2 PF12796.7 PSC77021.1 - 2.6e-20 72.8 0.4 1.5e-13 51.1 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 PSC77021.1 - 4.5e-19 68.3 4.0 5.7e-11 42.4 0.4 3.2 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 PSC77021.1 - 1.7e-18 66.7 0.3 1e-10 41.9 0.1 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 PSC77021.1 - 6.4e-16 58.0 4.6 4.8e-05 23.6 0.1 3.6 3 0 0 3 3 3 3 Ankyrin repeat Ank_3 PF13606.6 PSC77021.1 - 2.3e-13 49.0 0.3 0.0061 17.0 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat DUF2358 PF10184.9 PSC77022.1 - 4.3e-12 46.3 0.0 5.6e-12 45.9 0.0 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2358) SnoaL_2 PF12680.7 PSC77022.1 - 0.0031 18.1 0.1 0.026 15.2 0.0 2.3 1 1 2 3 3 3 1 SnoaL-like domain MAT1-1-2 PF17043.5 PSC77022.1 - 0.082 12.8 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Mating type protein 1-1-2 of unknown function Stig1 PF04885.13 PSC77023.1 - 1.2e-05 25.8 41.2 4.2e-05 24.1 10.2 3.8 1 1 2 3 3 3 2 Stigma-specific protein, Stig1 bZIP_1 PF00170.21 PSC77023.1 - 8.4e-05 22.6 7.9 0.00023 21.2 7.9 1.7 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 PSC77023.1 - 0.00021 21.3 6.2 0.00021 21.3 6.2 2.1 2 0 0 2 2 2 1 Basic region leucine zipper Striatin PF08232.12 PSC77023.1 - 0.39 11.3 6.0 0.11 13.1 0.7 2.4 2 0 0 2 2 2 0 Striatin family CNDH2_N PF06278.11 PSC77023.1 - 2.3 8.5 3.6 2.3 8.4 0.0 2.7 3 0 0 3 3 3 0 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal zf-RING_2 PF13639.6 PSC77025.1 - 1.4e-12 47.7 6.4 4.1e-12 46.2 6.4 1.9 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 PSC77025.1 - 9.9e-09 35.4 5.1 3.4e-08 33.6 5.1 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 PSC77025.1 - 3e-08 33.4 6.7 1e-07 31.6 6.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 PSC77025.1 - 4.8e-08 32.7 4.6 1.1e-07 31.6 4.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 PSC77025.1 - 6.8e-08 32.4 3.7 2e-07 30.9 3.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 PSC77025.1 - 8.5e-07 28.6 1.8 8.5e-07 28.6 1.8 2.4 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_5 PF14634.6 PSC77025.1 - 3.5e-06 26.9 4.9 7.2e-06 25.9 4.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 PSC77025.1 - 0.00013 21.7 2.6 0.00026 20.8 2.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 PSC77025.1 - 0.041 13.7 1.5 0.17 11.7 1.0 2.1 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 PSC77025.1 - 0.046 13.8 5.6 0.16 12.0 5.6 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 PSC77025.1 - 0.099 12.5 4.9 0.75 9.7 4.8 2.4 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 PSC77025.1 - 0.12 12.6 4.5 0.28 11.4 4.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zf_RING PF16744.5 PSC77025.1 - 0.12 12.5 1.7 1.5 9.0 2.5 2.2 2 0 0 2 2 2 0 KIAA1045 RING finger Zn_ribbon_17 PF17120.5 PSC77025.1 - 0.6 9.8 6.8 0.35 10.5 4.4 1.8 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 PSC77025.1 - 1.6 8.9 5.5 4 7.6 5.5 1.7 1 0 0 1 1 1 0 RING-variant domain zf-RING-like PF08746.11 PSC77025.1 - 1.9 8.9 5.9 5.6 7.4 5.9 1.9 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 PSC77025.1 - 2.5 8.4 4.9 8.6 6.6 4.9 1.9 1 1 0 1 1 1 0 FANCL C-terminal domain RNA_pol_Rpc4 PF05132.14 PSC77026.1 - 0.0013 19.2 1.6 0.0018 18.7 1.6 1.1 1 0 0 1 1 1 1 RNA polymerase III RPC4 DUF719 PF05334.13 PSC77026.1 - 0.0077 16.5 4.5 0.0099 16.1 4.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF719) CSRNP_N PF16019.5 PSC77026.1 - 0.0078 16.1 3.5 0.01 15.8 3.5 1.1 1 0 0 1 1 1 1 Cysteine/serine-rich nuclear protein N-terminus AP3D1 PF06375.11 PSC77026.1 - 0.057 13.7 18.3 0.091 13.0 18.3 1.3 1 0 0 1 1 1 0 AP-3 complex subunit delta-1 CCDC53 PF10152.9 PSC77026.1 - 0.1 13.0 3.5 0.13 12.6 3.5 1.1 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex AIF_C PF14721.6 PSC77026.1 - 0.15 12.4 2.2 0.18 12.2 2.2 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF755 PF05501.11 PSC77026.1 - 0.28 11.5 23.7 0.34 11.2 23.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Med19 PF10278.9 PSC77026.1 - 0.34 10.8 19.7 0.44 10.5 19.7 1.1 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 DUF1840 PF08895.11 PSC77026.1 - 0.53 10.6 7.7 0.72 10.2 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) Coilin_N PF15862.5 PSC77026.1 - 1.2 9.0 13.4 1.4 8.7 13.4 1.1 1 0 0 1 1 1 0 Coilin N-terminus RNA_polI_A34 PF08208.11 PSC77026.1 - 2.2 8.3 24.2 2.8 8.0 24.2 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 Rtf2 PF04641.12 PSC77026.1 - 3.3 7.0 17.3 3.9 6.7 17.3 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger DUF4603 PF15376.6 PSC77026.1 - 4.5 4.5 12.7 4.9 4.4 12.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Vfa1 PF08432.10 PSC77026.1 - 4.7 7.5 16.9 5.5 7.3 16.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Peptidase_S49_N PF08496.10 PSC77026.1 - 5.5 7.0 15.2 7.4 6.6 15.2 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4692 PF15763.5 PSC77026.1 - 6.5 7.2 7.7 8 6.9 7.7 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Casc1 PF12366.8 PSC77026.1 - 7.4 6.0 8.9 9 5.7 8.9 1.0 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 MAP17 PF15807.5 PSC77026.1 - 9 6.5 8.4 14 5.9 8.4 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 NUDIX PF00293.28 PSC77027.1 - 1.7e-08 34.6 0.0 2.6e-08 34.0 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Hydrolase PF00702.26 PSC77028.1 - 9.9e-16 58.7 0.0 1.6e-15 58.0 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 PSC77028.1 - 2e-13 51.2 0.0 5e-13 49.9 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Put_Phosphatase PF06888.12 PSC77028.1 - 0.0012 18.3 0.0 0.0028 17.1 0.0 1.5 1 1 0 1 1 1 1 Putative Phosphatase DUF455 PF04305.14 PSC77030.1 - 2.4e-77 259.8 0.1 2.2e-76 256.7 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF455) UvrD-helicase PF00580.21 PSC77030.1 - 9.4e-46 156.8 0.0 3.2e-45 155.0 0.0 1.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UDPG_MGDP_dh_N PF03721.14 PSC77030.1 - 5.5e-38 130.4 0.0 9e-38 129.7 0.0 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain AAA_19 PF13245.6 PSC77030.1 - 9.1e-23 81.2 0.0 3.9e-22 79.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain UvrD_C PF13361.6 PSC77030.1 - 3.3e-08 33.3 0.0 6e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 UvrD-like helicase C-terminal domain Bac_rhamnosid6H PF17389.2 PSC77030.1 - 0.19 10.9 0.0 0.38 10.0 0.0 1.4 1 0 0 1 1 1 0 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain DUF1840 PF08895.11 PSC77030.1 - 2.6 8.4 11.0 18 5.7 5.9 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) GGDEF_2 PF17853.1 PSC77030.1 - 5.5 7.3 11.6 0.068 13.4 0.9 3.6 4 0 0 4 4 4 0 GGDEF-like domain Sec23_trunk PF04811.15 PSC77031.1 - 3.2e-63 213.6 0.0 4.3e-63 213.1 0.0 1.2 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 PSC77031.1 - 2.6e-27 95.4 0.2 7.8e-27 93.9 0.0 1.9 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 PSC77031.1 - 2.2e-20 72.4 0.0 4.2e-20 71.5 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 PSC77031.1 - 2.2e-15 56.4 3.8 5.1e-15 55.2 3.8 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 PSC77031.1 - 3.5e-15 55.7 0.0 1e-14 54.2 0.0 1.8 2 0 0 2 2 2 1 Gelsolin repeat Vps36-NZF-N PF16988.5 PSC77031.1 - 0.52 9.7 1.9 1.8 8.0 0.0 2.3 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain PPR_2 PF13041.6 PSC77032.1 - 1.4e-76 252.5 0.0 1.3e-11 44.5 0.0 8.9 2 1 7 9 9 9 8 PPR repeat family PPR PF01535.20 PSC77032.1 - 4.8e-63 205.1 2.0 8.2e-09 35.1 0.0 10.1 10 0 0 10 10 10 8 PPR repeat PPR_3 PF13812.6 PSC77032.1 - 1.8e-57 191.3 0.0 4.5e-15 55.5 0.0 5.4 4 1 1 5 5 5 5 Pentatricopeptide repeat domain PPR_1 PF12854.7 PSC77032.1 - 5.5e-54 179.5 0.0 3.8e-07 29.7 0.0 9.7 10 0 0 10 10 10 8 PPR repeat PPR_long PF17177.4 PSC77032.1 - 9.8e-32 110.0 0.0 5.7e-16 58.5 0.0 4.0 3 1 4 7 7 7 5 Pentacotripeptide-repeat region of PRORP TPR_14 PF13428.6 PSC77032.1 - 3.4e-05 24.3 22.5 1.9 9.5 0.0 8.9 4 2 4 8 8 7 2 Tetratricopeptide repeat Cyclin_C PF02984.19 PSC77032.1 - 4.5e-05 23.5 0.1 0.00011 22.3 0.1 1.6 1 0 0 1 1 1 1 Cyclin, C-terminal domain Glyco_trans_4_3 PF12000.8 PSC77032.1 - 0.022 14.5 0.1 59 3.3 0.0 4.1 3 1 2 5 5 5 0 Glycosyl transferase family 4 group TPR_6 PF13174.6 PSC77032.1 - 0.028 15.0 8.1 43 5.0 0.1 6.4 6 0 0 6 6 5 0 Tetratricopeptide repeat TFIIB PF00382.19 PSC77032.1 - 0.046 13.8 1.3 0.52 10.4 0.4 2.9 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Wzy_C_2 PF11846.8 PSC77032.1 - 0.047 13.6 2.6 6.3 6.7 0.1 3.8 4 0 0 4 4 4 0 Virulence factor membrane-bound polymerase, C-terminal MRP-S27 PF10037.9 PSC77032.1 - 0.085 11.7 0.0 0.22 10.4 0.0 1.7 2 0 0 2 2 2 0 Mitochondrial 28S ribosomal protein S27 Radical_SAM PF04055.21 PSC77032.1 - 0.15 12.4 0.0 0.94 9.8 0.0 2.1 2 1 0 2 2 2 0 Radical SAM superfamily DUF3086 PF11285.8 PSC77032.1 - 0.2 10.7 0.0 0.42 9.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) Cyclin_N PF00134.23 PSC77032.1 - 0.28 10.9 0.5 0.85 9.4 0.0 1.9 2 0 0 2 2 2 0 Cyclin, N-terminal domain zf-CDGSH PF09360.10 PSC77033.1 - 3.6e-07 30.3 0.0 5.4e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type Ribonuclease_T2 PF00445.18 PSC77036.1 - 6.3e-37 127.6 0.0 8.1e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Ribonuclease T2 family Fasciclin PF02469.22 PSC77036.1 - 1.3e-05 25.4 0.0 2.1e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Fasciclin domain DUF1155 PF06633.11 PSC77036.1 - 0.11 12.0 0.4 0.31 10.6 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1155) F-box-like PF12937.7 PSC77037.1 - 9.4e-06 25.4 1.6 0.00012 21.9 0.6 2.6 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 PSC77037.1 - 0.0094 15.8 0.1 0.029 14.2 0.1 1.9 1 0 0 1 1 1 1 F-box domain TPR_1 PF00515.28 PSC77038.1 - 1.9e-11 43.3 3.7 0.00045 19.9 0.1 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat PB1 PF00564.24 PSC77038.1 - 1.5e-09 37.6 0.0 7e-09 35.5 0.0 2.1 2 0 0 2 2 2 1 PB1 domain TPR_2 PF07719.17 PSC77038.1 - 9.7e-07 28.5 18.3 0.026 14.6 0.0 5.4 5 0 0 5 5 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 PSC77038.1 - 8.5e-05 22.2 3.6 0.0028 17.3 0.0 3.8 3 0 0 3 3 3 1 TPR repeat TPR_8 PF13181.6 PSC77038.1 - 0.00012 22.1 6.4 0.21 11.9 0.1 4.0 4 0 0 4 4 3 2 Tetratricopeptide repeat ANAPC3 PF12895.7 PSC77038.1 - 0.0018 18.5 5.7 0.0031 17.7 3.7 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 PSC77038.1 - 0.0052 17.4 0.0 0.0052 17.4 0.0 6.0 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 PSC77038.1 - 0.0088 16.2 2.1 0.16 12.1 1.1 3.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 PSC77038.1 - 0.012 15.9 2.5 0.091 13.2 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 PSC77038.1 - 0.063 13.3 2.9 1.2 9.3 0.0 3.6 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 PSC77038.1 - 0.097 13.0 0.4 0.097 13.0 0.4 4.4 5 1 0 5 5 3 0 Tetratricopeptide repeat His_Phos_1 PF00300.22 PSC77039.1 - 7.6e-15 55.1 5.6 1.9e-10 40.7 1.2 2.8 2 1 0 2 2 2 2 Histidine phosphatase superfamily (branch 1) Tet_res_leader PF08050.12 PSC77041.1 - 0.2 11.5 0.7 0.37 10.7 0.7 1.3 1 0 0 1 1 1 0 Tetracycline resistance leader peptide PseudoU_synth_2 PF00849.22 PSC77043.1 - 4.2e-20 72.4 0.0 2.2e-19 70.1 0.0 2.0 1 1 0 1 1 1 1 RNA pseudouridylate synthase Sod_Fe_C PF02777.18 PSC77044.1 - 1.3e-36 124.9 0.4 2.7e-36 123.8 0.1 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 PSC77044.1 - 2.4e-25 88.8 0.2 4e-25 88.1 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, alpha-hairpin domain TPR_9 PF13371.6 PSC77044.1 - 0.0014 18.8 4.7 0.009 16.1 2.4 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 PSC77044.1 - 0.004 17.1 1.5 2.7 8.3 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 PSC77044.1 - 0.011 16.4 4.2 0.62 11.0 0.1 3.1 2 1 1 3 3 3 0 Tetratricopeptide repeat Mob_synth_C PF06463.13 PSC77045.1 - 3.2e-35 120.9 0.0 8.8e-35 119.4 0.0 1.8 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 PSC77045.1 - 1.3e-30 107.0 0.0 2.2e-30 106.3 0.0 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 PSC77045.1 - 4e-07 30.4 0.0 7.3e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 PSC77045.1 - 0.00088 19.4 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain Complex1_LYR PF05347.15 PSC77046.1 - 3.9e-13 49.2 0.1 4.9e-13 48.9 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.6 PSC77046.1 - 0.0004 20.9 0.5 0.0006 20.4 0.5 1.4 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_2 PF13233.6 PSC77046.1 - 0.011 16.4 0.1 0.014 16.2 0.1 1.1 1 0 0 1 1 1 0 Complex1_LYR-like DUF4231 PF14015.6 PSC77047.1 - 0.028 14.9 7.1 1.1 9.8 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF4231) RTA1 PF04479.13 PSC77047.1 - 1.6 8.3 5.9 0.75 9.4 1.2 2.0 1 1 0 2 2 2 0 RTA1 like protein UvrD-helicase PF00580.21 PSC77048.1 - 2e-45 155.7 0.0 6.6e-45 154.0 0.0 1.8 1 1 0 1 1 1 1 UvrD/REP helicase N-terminal domain UvrD_C PF13361.6 PSC77048.1 - 5e-30 105.1 0.0 3e-14 53.2 0.0 2.3 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.6 PSC77048.1 - 2.5e-22 79.8 0.0 1.4e-21 77.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain UvrD_C_2 PF13538.6 PSC77048.1 - 1.1e-10 41.2 0.2 1.5e-05 24.7 0.0 2.7 2 0 0 2 2 2 2 UvrD-like helicase C-terminal domain LysM PF01476.20 PSC77048.1 - 0.00066 19.7 0.0 0.0015 18.6 0.0 1.6 1 0 0 1 1 1 1 LysM domain DUF3318 PF11780.8 PSC77048.1 - 0.12 12.3 1.2 0.29 11.1 1.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) BAF1_ABF1 PF04684.13 PSC77048.1 - 0.53 9.3 2.8 0.79 8.7 2.8 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF1840 PF08895.11 PSC77048.1 - 6.5 7.1 7.0 16 5.9 5.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) Pkinase PF00069.25 PSC77050.1 - 6.8e-41 140.4 0.0 6.1e-34 117.6 0.0 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 PSC77050.1 - 4.7e-23 81.8 0.0 7.6e-20 71.3 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 PSC77050.1 - 0.00036 20.5 2.4 0.00066 19.7 0.2 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 PSC77050.1 - 0.00041 19.3 0.0 0.0012 17.7 0.0 1.7 1 1 1 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 PSC77050.1 - 0.00076 18.9 0.2 0.00076 18.9 0.2 2.2 2 1 0 2 2 2 1 Kinase-like DUF3235 PF11574.8 PSC77051.1 - 0.13 13.1 3.6 0.58 11.0 3.6 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF3235) ABATE PF07336.11 PSC77051.1 - 4.6 7.9 7.9 0.96 10.1 0.4 2.7 2 1 0 2 2 2 0 Putative stress-induced transcription regulator Aa_trans PF01490.18 PSC77053.1 - 2.7e-51 174.6 14.6 3.8e-51 174.1 14.6 1.2 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein 7TMR-DISM_7TM PF07695.11 PSC77053.1 - 1.5 8.7 17.7 0.064 13.1 10.8 2.2 2 1 0 2 2 2 0 7TM diverse intracellular signalling GYF_2 PF14237.6 PSC77055.1 - 3.6e-07 29.9 0.1 0.00042 20.0 0.0 3.9 4 0 0 4 4 4 2 GYF domain 2 JHD PF17811.1 PSC77055.1 - 4.6e-06 27.1 0.1 1.9e-05 25.1 0.0 2.0 2 0 0 2 2 2 1 Jumonji helical domain JmjC PF02373.22 PSC77055.1 - 3.3e-05 24.3 0.0 3.3e-05 24.3 0.0 3.3 3 1 0 3 3 3 1 JmjC domain, hydroxylase Cupin_8 PF13621.6 PSC77055.1 - 0.00036 20.3 3.3 0.00071 19.4 0.0 2.7 2 1 0 2 2 2 1 Cupin-like domain GYF PF02213.16 PSC77055.1 - 0.00062 19.4 0.4 0.22 11.2 0.0 2.7 3 0 0 3 3 3 2 GYF domain Herpes_env PF01673.18 PSC77055.1 - 2 7.2 3.5 2.4 7.0 0.7 2.2 2 0 0 2 2 2 0 Herpesvirus putative major envelope glycoprotein SAP PF02037.27 PSC77056.1 - 1.7e-07 30.9 0.6 0.0002 21.0 0.0 3.0 3 0 0 3 3 3 2 SAP domain V-ATPase_G_2 PF16999.5 PSC77056.1 - 0.26 11.7 4.9 0.14 12.6 1.9 2.0 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit SLX9 PF15341.6 PSC77057.1 - 1.5e-15 57.8 1.2 1.5e-15 57.8 1.2 2.3 2 0 0 2 2 2 1 Ribosome biogenesis protein SLX9 Mito_fiss_reg PF05308.11 PSC77057.1 - 0.037 14.1 1.4 0.037 14.1 1.4 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator Glutaredoxin PF00462.24 PSC77058.1 - 3.4e-16 59.2 0.0 4.9e-16 58.7 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin WHIM1 PF15612.6 PSC77058.1 - 0.13 11.9 0.0 0.3 10.7 0.0 1.6 1 0 0 1 1 1 0 WSTF, HB1, Itc1p, MBD9 motif 1 WD40 PF00400.32 PSC77059.1 - 9.8e-09 35.7 2.1 0.0045 17.8 0.4 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ_2 PF13360.6 PSC77059.1 - 0.0062 16.2 0.1 0.32 10.5 0.1 2.3 2 0 0 2 2 2 2 PQQ-like domain ANAPC4_WD40 PF12894.7 PSC77059.1 - 0.014 15.6 0.0 1 9.7 0.0 3.2 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain DENN PF02141.21 PSC77060.1 - 7.1e-34 117.4 1.3 3.1e-32 112.0 1.3 2.5 1 1 0 1 1 1 1 DENN (AEX-3) domain dDENN PF03455.19 PSC77060.1 - 1e-06 28.6 2.3 2.1e-06 27.6 2.3 1.6 1 0 0 1 1 1 1 dDENN domain Myb_DNA-binding PF00249.31 PSC77060.1 - 2.7e-06 27.5 0.0 5.3e-06 26.5 0.0 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain uDENN PF03456.18 PSC77060.1 - 6.1e-05 23.7 0.8 0.00012 22.8 0.1 1.9 2 0 0 2 2 2 1 uDENN domain OmpH PF03938.14 PSC77060.1 - 2 8.8 5.5 7.5 6.9 5.1 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) GST_N_3 PF13417.6 PSC77062.1 - 1.8e-28 98.8 0.0 5.5e-14 52.3 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Peptidase_M11 PF05548.11 PSC77062.1 - 2e-17 63.3 2.4 3.2e-17 62.7 2.4 1.2 1 0 0 1 1 1 1 Gametolysin peptidase M11 GST_N_2 PF13409.6 PSC77062.1 - 1.6e-09 37.9 0.0 0.0014 18.9 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 PSC77062.1 - 6e-08 32.9 0.0 0.012 15.9 0.0 2.4 2 0 0 2 2 2 2 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 PSC77062.1 - 0.00025 21.2 0.3 0.03 14.5 0.0 2.8 3 0 0 3 3 3 1 Glutaredoxin Reprolysin_3 PF13582.6 PSC77062.1 - 0.32 11.5 2.9 1.3 9.5 1.4 2.8 3 1 0 3 3 3 0 Metallo-peptidase family M12B Reprolysin-like DMRL_synthase PF00885.19 PSC77064.1 - 2.5e-40 137.6 1.1 3.1e-40 137.3 1.1 1.2 1 0 0 1 1 1 1 6,7-dimethyl-8-ribityllumazine synthase Pam16 PF03656.13 PSC77065.1 - 9.7e-25 87.0 0.6 1.2e-24 86.7 0.6 1.1 1 0 0 1 1 1 1 Pam16 Phage_capsid PF05065.13 PSC77065.1 - 0.0074 15.6 0.2 0.009 15.3 0.2 1.1 1 0 0 1 1 1 1 Phage capsid family Lipoprotein_16 PF03923.13 PSC77065.1 - 0.02 14.6 0.2 0.027 14.1 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized lipoprotein zf-CCHC PF00098.23 PSC77066.1 - 8.7e-22 76.2 37.3 3.1e-06 27.0 1.5 5.7 6 0 0 6 6 6 5 Zinc knuckle RGS-like PF09128.11 PSC77066.1 - 0.095 12.4 1.7 0.15 11.7 1.7 1.2 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain zf-CCHC_3 PF13917.6 PSC77066.1 - 0.13 12.2 29.9 0.54 10.3 0.2 5.4 4 1 2 6 6 6 0 Zinc knuckle zf-CCHC_4 PF14392.6 PSC77066.1 - 1.3 8.8 28.5 1 9.2 0.9 5.3 4 1 1 5 5 5 0 Zinc knuckle zinc_ribbon_4 PF13717.6 PSC77066.1 - 3.2 7.8 9.1 0.53 10.3 3.8 2.5 2 0 0 2 2 2 0 zinc-ribbon domain ATP-synt_10 PF05176.14 PSC77067.1 - 3.8e-30 105.0 0.0 2.5e-14 53.1 0.0 2.2 2 0 0 2 2 2 2 ATP10 protein DUF2385 PF09539.10 PSC77067.1 - 0.11 13.1 1.8 1.6 9.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2385) MEKHLA PF08670.11 PSC77067.1 - 0.35 10.8 0.1 0.35 10.8 0.1 2.0 2 0 0 2 2 2 0 MEKHLA domain Glyco_transf_49 PF13896.6 PSC77068.1 - 1e-09 38.2 0.0 4.3e-08 32.9 0.0 2.6 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Glyco_transf_49 PF13896.6 PSC77069.1 - 6.9e-11 42.1 0.0 8.8e-10 38.4 0.0 2.0 1 1 0 1 1 1 1 Glycosyl-transferase for dystroglycan Phageshock_PspD PF09584.10 PSC77069.1 - 0.21 11.6 1.7 6.1 6.9 0.4 2.6 2 0 0 2 2 2 0 Phage shock protein PspD (Phageshock_PspD) Peptidase_M18 PF02127.15 PSC77070.1 - 6.3e-148 493.1 0.0 8.9e-148 492.6 0.0 1.2 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) zf-C3HC4_3 PF13920.6 PSC77070.1 - 1.2e-15 57.1 14.3 2.1e-15 56.3 14.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 PSC77070.1 - 5e-08 32.7 12.7 1.1e-07 31.6 12.7 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 PSC77070.1 - 4.2e-06 27.0 15.0 1e-05 25.7 15.0 1.7 1 0 0 1 1 1 1 Ring finger domain Peptidase_M42 PF05343.14 PSC77070.1 - 0.0041 16.2 0.0 0.0074 15.3 0.0 1.4 1 0 0 1 1 1 1 M42 glutamyl aminopeptidase zf-RING_5 PF14634.6 PSC77070.1 - 0.0054 16.7 13.3 0.014 15.3 13.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 PSC77070.1 - 0.28 11.0 10.4 0.53 10.1 10.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 PSC77070.1 - 4 7.4 19.4 0.78 9.6 15.4 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) AAA_22 PF13401.6 PSC77071.1 - 0.002 18.4 0.0 0.0059 16.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.20 PSC77071.1 - 0.075 12.2 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 G-protein alpha subunit ABC_tran PF00005.27 PSC77071.1 - 0.085 13.4 0.0 0.24 11.9 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 PSC77071.1 - 0.14 12.0 0.0 0.35 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Chlorophyta/Micractinium_conductrix-ASM224581v2/GCA_002245815.2_ASM224581v2_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Chlorophyta/Micractinium_conductrix-ASM224581v2/GCA_002245815.2_ASM224581v2_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Chlorophyta/Micractinium_conductrix-ASM224581v2/GCA_002245815.2_ASM224581v2_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Chlorophyta/Micractinium_conductrix-ASM224581v2/GCA_002245815.2_ASM224581v2_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Sun Mar 24 06:04:31 2019 # [ok]